ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | rbags39f18 |
|---|---|
| Clone Library Name | barley_pub |
>C72A1_CATRO (Q05047) Cytochrome P450 72A1 (EC 1.3.3.9) (CYPLXXII) (Secologanin| synthase) (SLS) Length = 524 Score = 181 bits (458), Expect = 2e-45 Identities = 86/176 (48%), Positives = 118/176 (67%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSDL 479 LS HPEWQE+ REEVL+ G P + LN L V+M L E LRLY PV + + D Sbjct: 348 LSKHPEWQERAREEVLQAFGKNKPEFERLNHLKYVSMILYEVLRLYPPVIDLTKIVHKDT 407 Query: 478 EVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSGP 299 ++G +P GT + +P +HR+K +WGEDA EF PMRF +GVA A K+ L FS GP Sbjct: 408 KLGSYTIPAGTQVMLPTVMLHREKSIWGEDAMEFNPMRFVDGVANATKNNVTYLPFSWGP 467 Query: 298 RSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVHAPMDVITLRPKFGLPMILKSIE 131 R C+GQ+FA+++AK +A+ILQRF F ++P YVHAP ++T++P+FG +I K +E Sbjct: 468 RVCLGQNFALLQAKLGLAMILQRFKFDVAPSYVHAPFTILTVQPQFGSHVIYKKLE 523
>C13A3_CAEEL (Q27517) Putative cytochrome P450 CYP13A3 (EC 1.14.-.-)| Length = 520 Score = 114 bits (284), Expect = 3e-25 Identities = 67/161 (41%), Positives = 95/161 (59%), Gaps = 1/161 (0%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQ-RKAGSD 482 L+ HPE Q+KL+EEV REC T D L+KL + + ETLRLY S++ RK Sbjct: 342 LARHPEIQKKLQEEVDRECPDPEVTFDQLSKLKYMECVIKETLRLYPLASIVHNRKCMKS 401 Query: 481 LEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSG 302 V G+K+ EGT + T+H D + WGE+ANEFKP R+E+G +A A L F G Sbjct: 402 TTVLGMKIEEGTNVQADTWTLHYDPKFWGENANEFKPERWESGDEQA-VAKGAYLPFGLG 460 Query: 301 PRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVHAPMDVI 179 PR CIG A +E K ++A IL+++S + + H P+ ++ Sbjct: 461 PRICIGMRLAYMEEKMLLAQILKKYSLETTFE-THIPLKLV 500
>C13A7_CAEEL (Q27519) Putative cytochrome P450 CYP13A7 (EC 1.14.-.-)| Length = 518 Score = 113 bits (283), Expect = 4e-25 Identities = 65/158 (41%), Positives = 92/158 (58%), Gaps = 5/158 (3%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLI-QRKAGSD 482 L+THPE Q+KL+EEV REC T D L+KL + + E LRLY SL+ RK Sbjct: 342 LATHPEIQKKLQEEVDRECPDPEVTFDQLSKLKYLECVVKEALRLYPLASLVHNRKCLKT 401 Query: 481 LEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENG----VARAGKHPNALLS 314 V G+++ GT + + ++H D +VWG+D NEFKP R+E+G A+ G L Sbjct: 402 TNVLGMEIEAGTNINVDTWSLHHDPKVWGDDVNEFKPERWESGDELFFAKGG-----YLP 456 Query: 313 FSSGPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYV 200 F GPR CIG AM+E K ++ IL+ ++F +P+ V Sbjct: 457 FGMGPRICIGMRLAMMEMKMLLTNILKNYTFETTPETV 494
>C13A6_CAEEL (Q27515) Putative cytochrome P450 CYP13A6 (EC 1.14.-.-)| Length = 518 Score = 113 bits (282), Expect = 6e-25 Identities = 64/169 (37%), Positives = 93/169 (55%), Gaps = 4/169 (2%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTGDMLNKLHLVNMFLLETLRLYA-PVSLIQRKAGSD 482 L+THPE Q KL+EEV REC D L+KL + + ETLRLY + RK + Sbjct: 340 LATHPEIQTKLQEEVDRECPDPEIFFDHLSKLKYLECVMKETLRLYPLGTTANTRKCMRE 399 Query: 481 LEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSG 302 + G+ EG + + T+H + +WGED +FKP R+ENG +H + + F SG Sbjct: 400 TTINGVNFDEGMNIQVDTWTLHHNPRIWGEDVEDFKPERWENGACEHLEHNGSYIPFGSG 459 Query: 301 PRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVHAPMDVI---TLRPK 164 PR CIG A +E K ++A IL+ +SF + K P+ ++ TL P+ Sbjct: 460 PRQCIGMRLAQMEQKILLAQILKEYSFR-TTKNTQIPVKLVGKLTLSPE 507
>C13A4_CAEEL (Q27513) Putative cytochrome P450 CYP13A4 (EC 1.14.-.-)| Length = 520 Score = 112 bits (281), Expect = 7e-25 Identities = 64/154 (41%), Positives = 91/154 (59%), Gaps = 5/154 (3%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQ-RKAGSD 482 L+THPE Q+KL+EEV REC T D ++KL + + E LR+Y SL+ RK Sbjct: 342 LATHPEIQKKLQEEVDRECPDPEVTFDQISKLKYMECVVKEALRMYPLASLVHNRKCMKK 401 Query: 481 LEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENG----VARAGKHPNALLS 314 V G+++ EGT + + T+H D +VWG+DA+EFKP R+E G A+ G L Sbjct: 402 TNVLGVEIDEGTNVQVDTWTLHYDPKVWGDDASEFKPERWETGDELFYAKGG-----YLP 456 Query: 313 FSSGPRSCIGQSFAMIEAKAVIAVILQRFSFSLS 212 F GPR CIG AM+E K ++ IL++++F S Sbjct: 457 FGMGPRICIGMRLAMMEEKLLLTHILKKYTFDTS 490
>C13A5_CAEEL (Q27514) Putative cytochrome P450 CYP13A5 (EC 1.14.-.-)| Length = 520 Score = 112 bits (279), Expect = 1e-24 Identities = 62/154 (40%), Positives = 93/154 (60%), Gaps = 5/154 (3%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQ-RKAGSD 482 L+ HPE Q+KL+EEV REC + T D ++KL + + E LR+Y S++ RK + Sbjct: 342 LARHPEIQKKLQEEVDRECPNPEVTFDQISKLKYMECVVKEALRMYPLASIVHNRKCMKE 401 Query: 481 LEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENG----VARAGKHPNALLS 314 V G+++ +GT + + T+H D +VWGEDANEF+P R+E+G A+ G L Sbjct: 402 TNVLGVQIEKGTNVQVDTWTLHYDPKVWGEDANEFRPERWESGDELFYAKGG-----YLP 456 Query: 313 FSSGPRSCIGQSFAMIEAKAVIAVILQRFSFSLS 212 F GPR CIG AM+E K ++ IL++++F S Sbjct: 457 FGMGPRICIGMRLAMMEKKMLLTHILKKYTFETS 490
>CP3AC_CANFA (P24463) Cytochrome P450 3A12 (EC 1.14.14.1) (CYPIIIA12)| (P450-PBD-1) Length = 503 Score = 110 bits (275), Expect = 4e-24 Identities = 58/147 (39%), Positives = 91/147 (61%), Gaps = 1/147 (0%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSE-VPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSD 482 L+THP+ Q+KL+EE+ ++ +PT D L ++ ++M L ETLRLY ++R D Sbjct: 321 LATHPDVQQKLQEEIDATFPNKALPTYDALVQMEYLDMVLNETLRLYPIAGRLERVCKKD 380 Query: 481 LEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSG 302 +E+ G+ +P+GTV+ +P T+HRD+ +W E EF+P RF + +P L F +G Sbjct: 381 VEISGVFIPKGTVVMVPTFTLHRDQSLWPE-PEEFRPERFSR-KNKDSINPYTYLPFGTG 438 Query: 301 PRSCIGQSFAMIEAKAVIAVILQRFSF 221 PR+CIG FA++ K + +LQ FSF Sbjct: 439 PRNCIGMRFAIMNMKLALVRVLQNFSF 465
>CP4B1_RABIT (P15128) Cytochrome P450 4B1 (EC 1.14.14.1) (CYPIVB1) (P450-isozyme| 5) Length = 506 Score = 110 bits (274), Expect = 5e-24 Identities = 66/179 (36%), Positives = 102/179 (56%), Gaps = 4/179 (2%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVP-TGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSD 482 ++ +PE Q++ REEV G + + L K+ + M + E RLY PV + R+ Sbjct: 326 MALYPEHQQRCREEVREILGDQDSFQWEDLAKMTYLTMCMKECFRLYPPVPQVYRQLSKP 385 Query: 481 LE-VGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRF--ENGVARAGKHPNALLSF 311 + V G +P G+++++ I +HR+ +VW D F P+RF EN +G+HP A + F Sbjct: 386 VSFVDGRSLPAGSLISLHIYALHRNSDVW-PDPEVFDPLRFSPENS---SGRHPYAFIPF 441 Query: 310 SSGPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVHAPMDVITLRPKFGLPMILKSI 134 S+GPR+CIGQ FAM E K V A+ L RF FS+ P + + + LR K G+ + LK + Sbjct: 442 SAGPRNCIGQQFAMNEMKVVTALCLLRFEFSVDPLRLPIKLPQLVLRSKNGIHLYLKPL 500
>CP4B1_RAT (P15129) Cytochrome P450 4B1 (EC 1.14.14.1) (CYPIVB1) (P450-isozyme| 5) (P450 L-2) Length = 510 Score = 110 bits (274), Expect = 5e-24 Identities = 68/177 (38%), Positives = 99/177 (55%), Gaps = 2/177 (1%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVP-TGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSD 482 ++ +PE Q+ REEV G + D L K+ + M + E RLY PV + R+ Sbjct: 330 MALYPEHQQLCREEVRGILGDQDSFQWDDLAKMTYLTMCMKECFRLYPPVPQVYRQLNKP 389 Query: 481 LE-VGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSS 305 + V G +P G+++++ I +HR+ VW D F P+RF A AG+HP A + FS+ Sbjct: 390 VTFVDGRSLPAGSLISLHIYALHRNSTVW-PDPEVFDPLRFSPENA-AGRHPFAFMPFSA 447 Query: 304 GPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVHAPMDVITLRPKFGLPMILKSI 134 GPR+CIGQ FAM E K V A+ L RF FSL P + + + LR K G+ + LK + Sbjct: 448 GPRNCIGQQFAMNEMKVVTALCLLRFEFSLDPSKMPIKVPQLILRSKNGIHLYLKPL 504
>CP3AT_PIG (P79401) Cytochrome P450 3A29 (EC 1.14.14.1) (CYPIIIA29)| Length = 503 Score = 109 bits (273), Expect = 6e-24 Identities = 57/147 (38%), Positives = 91/147 (61%), Gaps = 1/147 (0%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVP-TGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSD 482 L+THP+ Q+KL+EE+ ++ P T D L ++ ++M + ETLRLY + ++R D Sbjct: 321 LATHPDVQQKLQEEIEATFPNKAPPTYDALAQMEYLDMVVNETLRLYPIAARLERACKKD 380 Query: 481 LEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSG 302 +E+ G+ VP+GTV+ +P+ +HRD ++W E EF+P RF + +P L F +G Sbjct: 381 VEIHGVFVPKGTVVVVPVFVLHRDPDLWPE-PEEFRPERFSK-KHKDTINPYTYLPFGTG 438 Query: 301 PRSCIGQSFAMIEAKAVIAVILQRFSF 221 PR+CIG FA++ K + +LQ FSF Sbjct: 439 PRNCIGMRFALMNMKLALVRVLQNFSF 465
>CP4D1_DROME (P33269) Cytochrome P450 4d1 (EC 1.14.-.-) (CYPIVD1)| Length = 512 Score = 108 bits (271), Expect = 1e-23 Identities = 63/176 (35%), Positives = 100/176 (56%), Gaps = 3/176 (1%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTG---DMLNKLHLVNMFLLETLRLYAPVSLIQRKAG 488 ++THPE Q+K EE+ G++ T ++LN+LH V++ + ETLR+Y V L+ RK Sbjct: 332 IATHPEAQKKCFEEIRSVVGNDKSTPVSYELLNQLHYVDLCVKETLRMYPSVPLLGRKVL 391 Query: 487 SDLEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFS 308 D E+ G +P GT + I + R +E++ E N FKP RF+ +P A + FS Sbjct: 392 EDCEINGKLIPAGTNIGISPLYLGRREELFSEP-NSFKPERFDVVTTAEKLNPYAYIPFS 450 Query: 307 SGPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVHAPMDVITLRPKFGLPMILK 140 +GPR+CIGQ FAM+E KA++A +L+ + P+ + L + P++ K Sbjct: 451 AGPRNCIGQKFAMLEIKAIVANVLRHYEVDFVGDSSEPPVLIAELILRTKEPLMFK 506
>CP4D1_DROSI (O16805) Cytochrome P450 4d1 (EC 1.14.-.-) (CYPIVD1)| Length = 512 Score = 108 bits (270), Expect = 1e-23 Identities = 63/176 (35%), Positives = 100/176 (56%), Gaps = 3/176 (1%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTG---DMLNKLHLVNMFLLETLRLYAPVSLIQRKAG 488 ++THPE Q+K EE+ G++ T ++LN+LH V++ + ETLR+Y V L+ RK Sbjct: 332 IATHPEAQKKCFEEIRSVVGNDKSTPVSYELLNQLHYVDLCVKETLRMYPSVPLLGRKVL 391 Query: 487 SDLEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFS 308 D E+ G +P GT + I + R +E++ E N FKP RF+ +P A + FS Sbjct: 392 EDCEINGKLIPAGTNIGISPLYLGRREELFSEP-NSFKPERFDVVTTAEKLNPYAYIPFS 450 Query: 307 SGPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVHAPMDVITLRPKFGLPMILK 140 +GPR+CIGQ FAM+E KA++A +L+ + P+ + L + P++ K Sbjct: 451 AGPRNCIGQKFAMLEIKAIVANVLRHYEVDFVGDSSEPPVLIAELILRTKDPLMFK 506
>CP3AO_SHEEP (Q29496) Cytochrome P450 3A24 (EC 1.14.14.1) (CYPIIIA24)| Length = 503 Score = 108 bits (269), Expect = 2e-23 Identities = 56/147 (38%), Positives = 90/147 (61%), Gaps = 1/147 (0%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVP-TGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSD 482 L+THP+ Q+KL+EE+ ++ P T D+L ++ ++M + ETLR++ + R D Sbjct: 321 LATHPDVQQKLQEEIDATFPNKAPPTYDVLAQMEYLDMVVNETLRMFPIAVRLDRLCKKD 380 Query: 481 LEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSG 302 +E+ G+ +P+GT +T+PI +HRD ++W E EF+P RF + +P L F +G Sbjct: 381 VEIHGVSIPKGTAVTVPIFVLHRDPQLWPE-PEEFRPERFSK-KNKDSINPYVYLPFGTG 438 Query: 301 PRSCIGQSFAMIEAKAVIAVILQRFSF 221 PR+CIG FA++ K I +LQ FSF Sbjct: 439 PRNCIGMRFAIMNMKLAIVRVLQNFSF 465
>CP4B1_HUMAN (P13584) Cytochrome P450 4B1 (EC 1.14.14.1) (CYPIVB1) (P450-HP)| Length = 511 Score = 106 bits (265), Expect = 5e-23 Identities = 66/177 (37%), Positives = 97/177 (54%), Gaps = 2/177 (1%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSE-VPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSD 482 ++ +PE Q + REEV G + D L K+ + M + E+ RLY PV + R+ Sbjct: 331 MALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKP 390 Query: 481 LE-VGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSS 305 + V G +P G+++++ I +HR+ VW D F +RF A + +HP A + FS+ Sbjct: 391 VTFVDGRSLPAGSLISMHIYALHRNSAVW-PDPEVFDSLRFSTENA-SKRHPFAFMPFSA 448 Query: 304 GPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVHAPMDVITLRPKFGLPMILKSI 134 GPR+CIGQ FAM E K V A+ L RF FSL P + M + LR K G + LK + Sbjct: 449 GPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKNGFHLHLKPL 505
>CP3A1_RAT (P04800) Cytochrome P450 3A1 (EC 1.14.14.1) (CYPIIIA1) (P450-PCN1)| Length = 504 Score = 106 bits (264), Expect = 7e-23 Identities = 57/147 (38%), Positives = 89/147 (60%), Gaps = 1/147 (0%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVP-TGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSD 482 L+THP+ Q+KL+EE+ R ++ P T D + ++ ++M L ETLRLY + ++R D Sbjct: 322 LATHPDTQKKLQEEIDRALPNKAPPTYDTVMEMEYLDMVLNETLRLYPIGNRLERVCKKD 381 Query: 481 LEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSG 302 +E+ G+ +P+G+V+ IP +HRD + W E EF+P RF + P L F +G Sbjct: 382 VEINGVFMPKGSVVMIPSYALHRDPQHWPE-PEEFRPERFSK-ENKGSIDPYVYLPFGNG 439 Query: 301 PRSCIGQSFAMIEAKAVIAVILQRFSF 221 PR+CIG FA++ K + +LQ FSF Sbjct: 440 PRNCIGMRFALMNMKLALTKVLQNFSF 466
>C13A1_CAEEL (Q27520) Putative cytochrome P450 CYP13A1 (EC 1.14.-.-)| Length = 519 Score = 105 bits (262), Expect = 1e-22 Identities = 57/153 (37%), Positives = 87/153 (56%), Gaps = 2/153 (1%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLI--QRKAGS 485 L+THPE Q+KL+EEV REC + T D L+KL + E LRLY P+ R+ Sbjct: 342 LATHPEIQKKLQEEVNRECPNPEVTIDQLSKLKYMECVFKEALRLY-PLGAFANSRRCMR 400 Query: 484 DLEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSS 305 + ++G +KV GT++ + T+H D +WG+DA +FKP R++ + + + F Sbjct: 401 NTKLGNMKVEVGTMIQVDTWTLHTDPNIWGDDAEDFKPERWQTPNSDQIYQKSGYIPFGL 460 Query: 304 GPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPK 206 GPR CIG A +E K ++ IL++F+F K Sbjct: 461 GPRQCIGMRLAYMEEKILLVHILRKFTFETGAK 493
>CP3AJ_CAPAE (P79152) Cytochrome P450 3A19 (EC 1.14.14.1) (CYPIIIA19) (Fragment)| Length = 218 Score = 104 bits (259), Expect = 3e-22 Identities = 56/162 (34%), Positives = 94/162 (58%), Gaps = 1/162 (0%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVP-TGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSD 482 L+THP+ Q+KL+EE+ ++ P T D L ++ ++M + ETLR++ ++R D Sbjct: 32 LATHPDVQQKLQEEIDATFPNKAPPTYDALVQMEYLDMVVNETLRMFPIAGRLERLCKKD 91 Query: 481 LEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSG 302 +E+ G+ +P+GT + +P+ +H + E W E EF+P RF + G +P L F +G Sbjct: 92 VEIHGVSIPKGTTVMVPLFVLHNNPEFWPE-PEEFRPERFSK-KNKDGINPYVYLPFGTG 149 Query: 301 PRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVHAPMDVIT 176 PR+C+G FA++ K + ILQ FSF + K P+ + T Sbjct: 150 PRNCVGMRFALMNIKLALVRILQNFSF-IPCKETQIPLKLYT 190
>C13AA_CAEEL (Q09653) Putative cytochrome P450 CYP13A10 (EC 1.14.-.-)| Length = 519 Score = 103 bits (257), Expect = 5e-22 Identities = 55/153 (35%), Positives = 91/153 (59%), Gaps = 2/153 (1%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLI--QRKAGS 485 L+THPE Q+KL+EE+ REC + D L+KL ++ + ETLRLY P+ + R+ Sbjct: 342 LATHPEVQKKLQEEIERECIEPSISFDHLSKLKYMDCIIKETLRLY-PLGTMANSRRCMR 400 Query: 484 DLEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSS 305 ++G ++V GT++ + ++H D ++WG+DA EFKP R+ + +SF Sbjct: 401 ATKLGNVEVEVGTMVQVDTWSLHTDTKIWGDDAKEFKPERWLDPNCDQVFQKGGYISFGL 460 Query: 304 GPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPK 206 GPR C+G A +E K ++A IL++++F + K Sbjct: 461 GPRQCVGMRLAYMEEKMLLAHILRKYTFEVGTK 493
>CP4B1_MOUSE (Q64462) Cytochrome P450 4B1 (EC 1.14.14.1) (CYPIVB1)| Length = 511 Score = 103 bits (256), Expect = 6e-22 Identities = 65/179 (36%), Positives = 97/179 (54%), Gaps = 4/179 (2%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVP-TGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSD 482 ++ +P Q++ REEV G D L ++ + M + E RLY PV + R+ Sbjct: 331 MALYPMHQQRCREEVREILGDRDSFQWDDLAQMTYLTMCMKECFRLYPPVPQVYRQLSKP 390 Query: 481 LE-VGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRF--ENGVARAGKHPNALLSF 311 + V G +P G+++++ I +HR+ VW D F P+RF EN G+HP A + F Sbjct: 391 VTFVDGRSLPAGSLISLHIYALHRNSAVW-PDPEVFDPLRFSPEN---MTGRHPFAFMPF 446 Query: 310 SSGPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVHAPMDVITLRPKFGLPMILKSI 134 S+GPR+CIGQ FAM E K V A+ L RF FS P + + + LR K G+ + LK + Sbjct: 447 SAGPRNCIGQQFAMNEMKVVTALCLLRFEFSPDPSKIPIKVPQLILRSKNGIHLYLKPL 505
>CP3AG_MOUSE (Q64481) Cytochrome P450 3A16 (EC 1.14.14.1) (CYPIIIA16)| Length = 504 Score = 102 bits (255), Expect = 8e-22 Identities = 56/147 (38%), Positives = 85/147 (57%), Gaps = 1/147 (0%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVP-TGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSD 482 L+THP+ Q+KL+EE+ ++ P T D + + ++M L ETLRLY + +QR D Sbjct: 322 LATHPDIQKKLQEEIDEALPNKAPPTYDTVMAMEYLDMVLNETLRLYPITNRLQRVCKKD 381 Query: 481 LEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSG 302 +E+ GI +P+G+ + IP +H D + W E EF+P RF + P L F +G Sbjct: 382 VEINGIYIPKGSTVIIPSYVLHHDPQHWPE-PEEFQPERFSK-ENKGSIDPYVYLPFGNG 439 Query: 301 PRSCIGQSFAMIEAKAVIAVILQRFSF 221 PR+CIG FA++ K + +LQ FSF Sbjct: 440 PRNCIGMRFALMNMKLALIKVLQNFSF 466
>CP3A2_RAT (P05183) Cytochrome P450 3A2 (EC 1.14.14.1) (CYPIIIA2) (P450-PCN2)| (P450/6-beta-A) (Testosterone 6-beta-hydroxylase) Length = 504 Score = 102 bits (255), Expect = 8e-22 Identities = 56/147 (38%), Positives = 88/147 (59%), Gaps = 1/147 (0%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVP-TGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSD 482 L+THP+ Q+KL+EE+ S+ P T D++ ++ ++M L ETLRLY + ++R D Sbjct: 322 LATHPDIQKKLQEEIDGALPSKAPPTYDIVMEMEYLDMVLNETLRLYPIGNRLERVCKKD 381 Query: 481 LEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSG 302 +E+ G+ +P+G+V+TIP +H D + W + EF P RF + P L F +G Sbjct: 382 IELDGLFIPKGSVVTIPTYALHHDPQHWPK-PEEFHPERFSK-ENKGSIDPYVYLPFGNG 439 Query: 301 PRSCIGQSFAMIEAKAVIAVILQRFSF 221 PR+CIG FA++ K + +LQ FSF Sbjct: 440 PRNCIGMRFALMNMKLALTKVLQNFSF 466
>CP3AF_CAVPO (Q64406) Cytochrome P450 3A15 (EC 1.14.14.1) (CYPIIIA15)| Length = 503 Score = 102 bits (254), Expect = 1e-21 Identities = 53/147 (36%), Positives = 89/147 (60%), Gaps = 1/147 (0%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEV-PTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSD 482 L+THP+ Q+KL +E+ + ++ PT D++ ++ ++M + ETLRLY + I+R + D Sbjct: 321 LATHPDVQKKLHQEIDKTLPNKAFPTYDVMMEMEYLDMVVNETLRLYPVANRIERMSKKD 380 Query: 481 LEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSG 302 E+ G+ P+GT++ IP +HRD + W E +EF+P RF + P + F +G Sbjct: 381 FEINGMSFPKGTLVMIPSFALHRDSKYWPE-PDEFRPERFSK-KNKENIDPYIYMPFGNG 438 Query: 301 PRSCIGQSFAMIEAKAVIAVILQRFSF 221 PR+CIG+ A++ K + +LQ FSF Sbjct: 439 PRNCIGRRMALMNLKLALIRLLQNFSF 465
>CP4A7_RABIT (P14581) Cytochrome P450 4A7 precursor (EC 1.14.15.3) (CYPIVA7)| (Lauric acid omega-hydroxylase) (P450-KA-2) Length = 511 Score = 102 bits (253), Expect = 1e-21 Identities = 64/177 (36%), Positives = 94/177 (53%), Gaps = 2/177 (1%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVP-TGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSD 482 L+THPE Q + REE+ G T + L+K+ M + E LRLY PV + K S Sbjct: 338 LATHPEHQHRCREEIQGLLGDGASITWEHLDKMPYTTMCIKEALRLYPPVPGVGSKLSSP 397 Query: 481 LEV-GGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSS 305 + G +P+G ++T+ I +H + +VW + F P RF G AR H +A L FS Sbjct: 398 VTFPDGRSLPKGIIITLSIYGLHHNPKVW-PNPEVFDPSRFAPGSAR---HSHAFLPFSG 453 Query: 304 GPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVHAPMDVITLRPKFGLPMILKSI 134 G R+CIG+ FAM E K +A+ L RF P V P+ + L+ K G+ + L+ + Sbjct: 454 GSRNCIGKQFAMNELKVAVALTLVRFELLPDPTRVPIPITRLVLKSKNGIHLRLRKL 510
>CP3AI_RAT (Q64581) Cytochrome P450 3A18 (EC 1.14.14.1) (CYPIIIA18)| (P450(6)beta-2) Length = 497 Score = 102 bits (253), Expect = 1e-21 Identities = 65/178 (36%), Positives = 100/178 (56%), Gaps = 3/178 (1%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVP-TGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSD 482 L+T P Q+KL+ E+ R ++ P T D L ++ ++M + E+LRLY + + R + D Sbjct: 321 LATRPNVQKKLQNEIDRALPNKAPVTYDALMEMEYLDMVVNESLRLYPIATRLDRVSKKD 380 Query: 481 LEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSG 302 +E+ G+ +P+GTV+TIPI +HR+ E W E EF P RF + P L F +G Sbjct: 381 VEINGVFIPKGTVVTIPIYPLHRNPEYWLE-PEEFNPERFSK-ENKGSIDPYVYLPFGNG 438 Query: 301 PRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVHAPMDVITLRPKFGL--PMILKSI 134 PR+CIG FA+I K + +LQ F+ K P+ I+ +P F P+ILK + Sbjct: 439 PRNCIGMRFALISMKLAVIGVLQNFNIQPCEK-TQIPLK-ISRQPIFQPEGPIILKLV 494
>CP3AH_CAVPO (Q64409) Cytochrome P450 3A17 (EC 1.14.14.1) (CYPIIIA17)| Length = 503 Score = 101 bits (252), Expect = 2e-21 Identities = 61/179 (34%), Positives = 103/179 (57%), Gaps = 4/179 (2%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEV-PTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSD 482 L+THP+ Q+KL++E+ + ++ PT D++ ++ ++M + ETLRLY + I+R + D Sbjct: 321 LATHPDVQKKLQQEIDKTLPNKAFPTYDVMMEMEYLDMVVNETLRLYPVTNRIERMSKKD 380 Query: 481 LEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSG 302 E+ G+ P+GT + IP +HRD + W E +EF+P RF + P + F +G Sbjct: 381 FEINGMSFPKGTGVMIPSFALHRDSKYWPE-PDEFRPERFSK-KNKENIDPYIYMPFGNG 438 Query: 301 PRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVHAPMDV---ITLRPKFGLPMILKSI 134 PR+CIG A++ K + +LQ FSF + K P+ + + L+P P+ILK + Sbjct: 439 PRNCIGMRMALMNLKLALIRLLQNFSF-YTCKETQIPLRLGSQVILQP--AKPIILKVV 494
>CP4A2_RAT (P20816) Cytochrome P450 4A2 precursor (EC 1.14.15.3) (CYPIVA2)| (Lauric acid omega-hydroxylase) (P450-LA-omega 2) (P450 K-5) (P-450 K-2) Length = 504 Score = 101 bits (252), Expect = 2e-21 Identities = 65/177 (36%), Positives = 92/177 (51%), Gaps = 2/177 (1%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVP-TGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSD 482 L+THPE QE+ REEV G T D L+++ M + E LRLY+PV + R+ S Sbjct: 331 LATHPEHQERCREEVQSILGDGTSVTWDHLDQMPYTTMCIKEALRLYSPVPSVSRELSSP 390 Query: 481 LEV-GGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSS 305 + G +P+G +TI I +H + W + F P RF R H +A L FS Sbjct: 391 VTFPDGRSIPKGIRVTILIYGLHHNPSYW-PNPKVFDPSRFSPDSPR---HSHAYLPFSG 446 Query: 304 GPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVHAPMDVITLRPKFGLPMILKSI 134 G R+CIG+ FAM E K +A+ L RF P + PM + L+ K G+ + LK + Sbjct: 447 GARNCIGKQFAMNELKVAVALTLLRFELLPDPTRIPVPMPRLVLKSKNGIHLRLKKL 503
>CP3AP_MOUSE (O09158) Cytochrome P450 3A25 (EC 1.14.14.1) (CYPIIIA25)| Length = 503 Score = 101 bits (251), Expect = 2e-21 Identities = 55/146 (37%), Positives = 87/146 (59%), Gaps = 1/146 (0%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVP-TGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSD 482 L+THP+ Q+KL++E+ R ++ P T D L + ++M + E+LRLY ++R + D Sbjct: 321 LATHPDVQKKLQDEIDRTLPNKAPVTYDALMDMEYLDMVVNESLRLYPIAIRLERVSKKD 380 Query: 481 LEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSG 302 +E+ G+ +P+GTV+ IPI +HR+ E W E EF P RF + P + F +G Sbjct: 381 VEINGVFIPKGTVVMIPIYPLHRNPEYWPE-PQEFCPERFSK-ENKGNIDPYIYMPFGNG 438 Query: 301 PRSCIGQSFAMIEAKAVIAVILQRFS 224 PR+CIG FA+I K + +LQ F+ Sbjct: 439 PRNCIGMRFALISIKLAVIGVLQNFT 464
>CP3AS_BOVIN (P79102) Cytochrome P450 3A28 (EC 1.14.14.1) (CYPIIIA28)| Length = 507 Score = 101 bits (251), Expect = 2e-21 Identities = 52/147 (35%), Positives = 87/147 (59%), Gaps = 1/147 (0%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVP-TGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSD 482 L+THP Q+KL+EE+ ++ P T D L ++ ++M + ETLR++ ++R D Sbjct: 321 LTTHPHVQQKLQEEIDATFPNKAPPTYDALVQMEYLDMVVNETLRMFPIAGRLERVCKKD 380 Query: 481 LEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSG 302 +E+ G+ +P+GT + +P+ +H + E+W E EF+P RF + +P L F +G Sbjct: 381 VEIHGVTIPKGTTVLVPLFVLHNNPELWPE-PEEFRPERFSKN-NKDSINPYVYLPFGTG 438 Query: 301 PRSCIGQSFAMIEAKAVIAVILQRFSF 221 PR+C+G FA++ K + ILQ FSF Sbjct: 439 PRNCLGMRFAIMNIKLALVRILQNFSF 465
>C4D10_DROMT (O18596) Cytochrome P450 4d10 (EC 1.14.-.-) (CYPIVD10)| Length = 513 Score = 101 bits (251), Expect = 2e-21 Identities = 58/176 (32%), Positives = 98/176 (55%), Gaps = 3/176 (1%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTG---DMLNKLHLVNMFLLETLRLYAPVSLIQRKAG 488 ++ +PE Q K EE++ G + T D+LN L+ +++ + ETLR+Y V L+ RK Sbjct: 333 IALYPECQRKCVEEIVSVLGKDTETPVTYDLLNNLNYMDLCIKETLRMYPSVPLLGRKVL 392 Query: 487 SDLEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFS 308 + E+ G +P GT + I + R +++ E N FKP RF+ + +P+A + FS Sbjct: 393 QECEINGKIIPAGTNIGISPLFLGRSEDISSEP-NTFKPERFDVVTSAEKLNPHAYIPFS 451 Query: 307 SGPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVHAPMDVITLRPKFGLPMILK 140 +GPR+CIGQ FAM+E KA+ A +L+ + +P+ + L + P++ K Sbjct: 452 AGPRNCIGQKFAMLEIKAIAANVLRHYEIEFVGNAEESPVLIAELILRTKDPLMFK 507
>CP3AE_CAVPO (Q64417) Cytochrome P450 3A14 (EC 1.14.14.1) (CYPIIIA14)| Length = 503 Score = 100 bits (250), Expect = 3e-21 Identities = 53/147 (36%), Positives = 88/147 (59%), Gaps = 1/147 (0%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEV-PTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSD 482 L+THP+ Q+KL++E+ + ++ PT D++ ++ ++M + ETLRLY + I+R + D Sbjct: 321 LATHPDVQKKLQQEIDKTLPNKAFPTYDVMMEMEYLDMVVNETLRLYPVTNRIERMSKKD 380 Query: 481 LEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSG 302 E+ G+ P+GT + IP +HRD + W E +EF+P RF + P + F +G Sbjct: 381 FEINGMSFPKGTGVMIPSFALHRDSKYWPE-PDEFRPERFSK-KNKENIDPYIYMPFGNG 438 Query: 301 PRSCIGQSFAMIEAKAVIAVILQRFSF 221 PR+CIG A++ K + +LQ FSF Sbjct: 439 PRNCIGMRMALMNLKLALIRLLQNFSF 465
>CP4AE_RAT (P20817) Cytochrome P450 4A14 precursor (EC 1.14.15.3) (CYPIVA14)| (Lauric acid omega-hydroxylase) (P450-LA-omega 3) Length = 507 Score = 100 bits (250), Expect = 3e-21 Identities = 65/177 (36%), Positives = 90/177 (50%), Gaps = 2/177 (1%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVP-TGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSD 482 L+THPE QE+ REEV G T D L+++ M + E LRLY PV + R+ S Sbjct: 334 LATHPEHQERCREEVQSILGDGTSVTWDHLDQIPYTTMCIKEALRLYPPVPSVSRELSSP 393 Query: 481 LEV-GGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSS 305 + G +P+G TI I +H + W + F P RF R H +A L FS Sbjct: 394 VTFPDGRSIPKGITTTILIYGLHHNPSYW-PNPKVFDPSRFSPDSPR---HSHAYLPFSG 449 Query: 304 GPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVHAPMDVITLRPKFGLPMILKSI 134 G R+CIG+ FAM E K +A+ L RF P + PM + L+ K G+ + LK + Sbjct: 450 GARNCIGKQFAMNELKVAVALTLLRFELLPDPTRIPVPMARLVLKSKNGIHLRLKKL 506
>CP3AD_MOUSE (Q64464) Cytochrome P450 3A13 (EC 1.14.14.1) (CYPIIIA13)| Length = 503 Score = 100 bits (249), Expect = 4e-21 Identities = 54/146 (36%), Positives = 87/146 (59%), Gaps = 1/146 (0%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVP-TGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSD 482 L+ HP+ Q+KL++E+ ++ P T D L ++ ++M + ETLRLY ++R +D Sbjct: 321 LAIHPDVQKKLQDEIDAALPNKAPATYDTLLQMEYLDMVVNETLRLYPIAGRLERVCKTD 380 Query: 481 LEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSG 302 +E+ G+ +P+GTV+ IP +H+D + W E EF+P RF + +P L F SG Sbjct: 381 VEINGLFIPKGTVVMIPTFALHKDPKYWPE-PEEFRPERFSK-KNQDSINPYMYLPFGSG 438 Query: 301 PRSCIGQSFAMIEAKAVIAVILQRFS 224 PR+CIG FA+I K + +LQ F+ Sbjct: 439 PRNCIGMRFALINMKVALVRVLQNFT 464
>CP4D2_DROME (Q27589) Cytochrome P450 4d2 (EC 1.14.-.-) (CYPIVD2)| Length = 501 Score = 100 bits (249), Expect = 4e-21 Identities = 67/178 (37%), Positives = 105/178 (58%), Gaps = 5/178 (2%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECG----SEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKA 491 +S HPE Q++L++E+ G S V D L +L + + E+LRL+ PV +I R Sbjct: 327 ISRHPEVQQRLQQEIRDVLGEDRKSPVTLRD-LGELKFMENVIKESLRLHPPVPMIGRWF 385 Query: 490 GSDLEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSF 311 D+E+ G +P GT T+ I + RD E + E +EF+P RF+ V + HP A + F Sbjct: 386 AEDVEIRGKHIPAGTNFTMGIFVLLRDPEYF-ESPDEFRPERFDADVPQI--HPYAYIPF 442 Query: 310 SSGPRSCIGQSFAMIEAKAVIAVILQRFS-FSLSPKYVHAPMDVITLRPKFGLPMILK 140 S+GPR+CIGQ FAM+E K+ ++ +L+ F L P+ H+ M+++ LR G+ + LK Sbjct: 443 SAGPRNCIGQKFAMLEMKSTVSKLLRHFELLPLGPEPRHS-MNIV-LRSANGVHLGLK 498
>CP4V3_MOUSE (Q9DBW0) Cytochrome P450 4V3 (EC 1.14.-.-)| Length = 525 Score = 100 bits (248), Expect = 5e-21 Identities = 72/179 (40%), Positives = 101/179 (56%), Gaps = 6/179 (3%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECG-SEVP-TGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGS 485 L T+PE Q K+ +E+ G S P T + L KL ++ + ETLR++ V L R Sbjct: 345 LGTNPEVQRKVDQELDEVFGRSHRPVTLEDLKKLKYLDCVIKETLRVFPSVPLFARSLSE 404 Query: 484 DLEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRF--ENGVARAGKHPNALLSF 311 D EVGG KV +GT I +HRD + D EF+P RF EN G+HP A + F Sbjct: 405 DCEVGGYKVTKGTEAIIIPYALHRDPRYF-PDPEEFRPERFFPENS---QGRHPYAYVPF 460 Query: 310 SSGPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVHAPM--DVITLRPKFGLPMILK 140 S+GPR+CIGQ FA++E K ++A IL++F + K + D+I LRP G+ + LK Sbjct: 461 SAGPRNCIGQKFAVMEEKTILACILRQFWVESNQKREELGLAGDLI-LRPNNGIWIKLK 518
>CP3AB_MOUSE (Q64459) Cytochrome P450 3A11 (EC 1.14.14.1) (CYPIIIA11)| (P-450IIIAM1) (P-450UT) Length = 504 Score = 100 bits (248), Expect = 5e-21 Identities = 52/147 (35%), Positives = 86/147 (58%), Gaps = 1/147 (0%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVP-TGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSD 482 L+THP+ Q+KL++E+ ++ P T D + ++ ++M L ETLRLY + ++R D Sbjct: 322 LATHPDIQKKLQDEIDEALPNKAPPTYDTVMEMEYLDMVLNETLRLYPIANRLERVCKKD 381 Query: 481 LEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSG 302 +E+ G+ +P+G+ + IP +H D + W E EF+P RF + P L F +G Sbjct: 382 VELNGVYIPKGSTVMIPSYALHHDPQHWSE-PEEFQPERFSK-ENKGSIDPYVYLPFGNG 439 Query: 301 PRSCIGQSFAMIEAKAVIAVILQRFSF 221 PR+C+G FA++ K + I+Q FSF Sbjct: 440 PRNCLGMRFALMNMKLALTKIMQNFSF 466
>CP3AV_MESAU (O70537) Cytochrome P450 3A31 (EC 1.14.14.1) (CYPIIIA31) (P450| SH3A-1) Length = 501 Score = 99.8 bits (247), Expect = 7e-21 Identities = 63/180 (35%), Positives = 104/180 (57%), Gaps = 5/180 (2%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEV-PTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSD 482 L+THP+ Q+KL+EE+ ++ P+ D + ++ ++M L ETLRLY S ++R D Sbjct: 319 LATHPDVQKKLQEEIDIALPNKARPSYDKVMEMEYLDMVLNETLRLYPIGSRLERVCKQD 378 Query: 481 LEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSG 302 +E+ G+ VP+G+++ +P+ +H D + W E +F+P RF + P L F +G Sbjct: 379 VEMDGVFVPKGSIVMVPVFALHYDPQYWPE-PEKFRPERFSK-ENKGSIDPYIFLPFGNG 436 Query: 301 PRSCIGQSFAMIEAKAVIAVILQRFSFSLSP-KYVHAPMDV---ITLRPKFGLPMILKSI 134 PR+CIG FA++ K + +LQ +FSL P K PM + L+P+ P+ILK + Sbjct: 437 PRNCIGMRFALMNMKLALTKVLQ--NFSLQPCKETQIPMKLSRKAMLQPE--KPIILKVV 492
>CP3A6_RABIT (P11707) Cytochrome P450 3A6 (EC 1.14.14.1) (CYPIIIA6) (P450-3C)| Length = 501 Score = 99.4 bits (246), Expect = 9e-21 Identities = 53/149 (35%), Positives = 87/149 (58%), Gaps = 1/149 (0%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLREC-GSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSD 482 L+THP+ Q+KL+EE+ E+ T D L K+ ++M + ETLRLY ++R D Sbjct: 319 LATHPDVQQKLQEEIDTLLPNKELATYDTLVKMEYLDMVVNETLRLYPIAGRLERVCKKD 378 Query: 481 LEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSG 302 +++ G +P+GT++ +P +HRD + W E +EF+P RF + +P F +G Sbjct: 379 VDINGTFIPKGTIVMMPTYALHRDPQHWTE-PDEFRPERFSK-KNKDNINPYIYHPFGAG 436 Query: 301 PRSCIGQSFAMIEAKAVIAVILQRFSFSL 215 PR+C+G FA++ K + ++Q FSF L Sbjct: 437 PRNCLGMRFALMNIKLALVRLMQNFSFKL 465
>CP4A6_RABIT (P14580) Cytochrome P450 4A6 precursor (EC 1.14.15.3) (CYPIVA6)| (Lauric acid omega-hydroxylase) (P450-KA-1) Length = 510 Score = 99.0 bits (245), Expect = 1e-20 Identities = 62/177 (35%), Positives = 93/177 (52%), Gaps = 2/177 (1%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVP-TGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSD 482 L+THPE Q + REE+ G T + L+++ M + E LRLY PV + R+ S Sbjct: 337 LATHPEHQHRCREEIQGLLGDGASITWEHLDQMPYTTMCIKEALRLYPPVPGVGRQLSSP 396 Query: 481 LEV-GGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSS 305 + G +P+G ++T+ I +H + +VW + F P F G AR H +A L FS Sbjct: 397 VTFPDGRSLPKGVIVTLSIYALHHNPKVW-PNPEVFDPFPFAPGSAR---HSHAFLPFSG 452 Query: 304 GPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVHAPMDVITLRPKFGLPMILKSI 134 GPR+CIG+ FAM E K +A+ L RF PK V + L+ G+ + L+ + Sbjct: 453 GPRNCIGKQFAMNELKVAVALTLVRFELLPDPKRVPDQKPRLVLKSSNGIHLRLRKL 509
>CP4AE_MOUSE (O35728) Cytochrome P450 4A14 precursor (EC 1.14.15.3) (CYPIVA14)| (Lauric acid omega-hydroxylase 3) (P450-LA-omega 3) Length = 507 Score = 98.2 bits (243), Expect = 2e-20 Identities = 62/177 (35%), Positives = 89/177 (50%), Gaps = 2/177 (1%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVP-TGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSD 482 L+THPE Q++ REEV G T D L ++ M + E LRLY PV + R+ S Sbjct: 334 LATHPEHQQRCREEVQSILGDGTSVTWDHLGQMPYTTMCIKEALRLYPPVISVSRELSSP 393 Query: 481 LEV-GGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSS 305 + G +P+G TI I +H + W + F P RF + H +A L FS Sbjct: 394 VTFPDGRSIPKGITATISIYGLHHNPRFW-PNPKVFDPSRF---APDSSHHSHAYLPFSG 449 Query: 304 GPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVHAPMDVITLRPKFGLPMILKSI 134 G R+CIG+ FAM E K +A+ L RF P + P+ + L+ K G+ + LK + Sbjct: 450 GSRNCIGKQFAMNELKVAVALTLLRFELLPDPTRIPVPIARLVLKSKNGIHLCLKKL 506
>CP3A9_RAT (P51538) Cytochrome P450 3A9 (EC 1.14.14.1) (CYPIIIA9) (P450-OLF3)| (Olfactive) (3AH15) Length = 503 Score = 97.8 bits (242), Expect = 2e-20 Identities = 53/147 (36%), Positives = 86/147 (58%), Gaps = 1/147 (0%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEV-PTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSD 482 L+ HP+ Q+KL++E+ ++ T D L ++ ++M + ETLRLY ++R +D Sbjct: 321 LAIHPDIQKKLQDEIDAALPNKAHATYDTLLQMEYLDMVVNETLRLYPIAGRLERVCKTD 380 Query: 481 LEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSG 302 +E+ G+ +P+GTV+ IP +H+D W E EF+P RF + +P L F +G Sbjct: 381 VEINGVFIPKGTVVMIPTFALHKDPHYWPE-PEEFRPERFSK-KNQDNINPYMYLPFGNG 438 Query: 301 PRSCIGQSFAMIEAKAVIAVILQRFSF 221 PR+CIG FA++ K + +LQ FSF Sbjct: 439 PRNCIGMRFALMNMKVALFRVLQNFSF 465
>CP4X1_RAT (Q8K4D6) Cytochrome P450 4X1 (EC 1.14.14.1) (CYPIVX1)| Length = 507 Score = 97.8 bits (242), Expect = 2e-20 Identities = 67/180 (37%), Positives = 96/180 (53%), Gaps = 5/180 (2%) Frame = -1 Query: 658 LSTHPEWQEKLREEV--LRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGS 485 L+ +PE Q++ R E+ + GS + T + L+++ M + ETLRL P+ I R+ Sbjct: 330 LALNPEHQDRCRTEIRSILGDGSSI-TWEQLDEIPYTTMCIKETLRLIPPIPSISRELSK 388 Query: 484 DLEV-GGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRF--ENGVARAGKHPNALLS 314 L + G +P G + + I +H + VW +D F P+RF EN R HP A L Sbjct: 389 PLTLPDGHSLPAGMTVVLSIWGLHHNPAVW-KDPKVFDPLRFTKENSEQR---HPCAFLP 444 Query: 313 FSSGPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVHAPMDVITLRPKFGLPMILKSI 134 FSSGPR+CIGQ FAM+E K IA+ L RF + A LRPK G+ + LK + Sbjct: 445 FSSGPRNCIGQQFAMLELKVAIALTLLRFRVAADLTRPPAFSSHTVLRPKHGIYLHLKKL 504
>CP4AA_MOUSE (O88833) Cytochrome P450 4A10 (EC 1.14.15.3) (CYPIVA10) (Lauric| acid omega-hydroxylase) (P450-LA-omega 1) (P452) Length = 509 Score = 97.8 bits (242), Expect = 2e-20 Identities = 64/178 (35%), Positives = 97/178 (54%), Gaps = 3/178 (1%) Frame = -1 Query: 658 LSTHPEWQEKLREEV--LRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGS 485 L+THP+ Q++ REEV L GS + T D L+++ M + E LRLY PV I R+ + Sbjct: 336 LATHPDHQQRCREEVQSLLGDGSSI-TWDHLDQIPYTTMCIKEALRLYPPVPGIVRELST 394 Query: 484 DLEV-GGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFS 308 + G +P+G +T+ I +H + +VW + F P RF R H ++ L FS Sbjct: 395 SVTFPDGRSLPKGVQVTLSIYGLHHNPKVW-PNPEVFDPSRFAPDSPR---HSHSFLPFS 450 Query: 307 SGPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVHAPMDVITLRPKFGLPMILKSI 134 G R+CIG+ FAM E K ++A+ L RF P V P+ + L+ K G+ + LK + Sbjct: 451 GGARNCIGKQFAMSELKVIVALTLLRFELLPDPTRVPMPLARLVLKSKNGIYLHLKKL 508
>CP4AA_RAT (P08516) Cytochrome P450 4A10 (EC 1.14.15.3) (CYPIVA10) (Lauric| acid omega-hydroxylase) (P450-LA-omega 1) (P452) Length = 509 Score = 97.4 bits (241), Expect = 3e-20 Identities = 62/177 (35%), Positives = 94/177 (53%), Gaps = 2/177 (1%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVP-TGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSD 482 L+THP+ Q++ REEV G T D L+++ M + E LRLY PV I R+ + Sbjct: 336 LATHPKHQQRCREEVQSVLGDGSSITWDHLDQIPYTTMCIKEALRLYPPVPGIVRELSTS 395 Query: 481 LEV-GGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSS 305 + G +P+G +T+ I +H + +VW + F P RF R H ++ L FS Sbjct: 396 VTFPDGRSLPKGIQVTLSIYGLHHNPKVW-PNPEVFDPSRFAPDSPR---HSHSFLPFSG 451 Query: 304 GPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVHAPMDVITLRPKFGLPMILKSI 134 G R+CIG+ FAM E K ++A+ L RF P V P+ + L+ K G+ + LK + Sbjct: 452 GARNCIGKQFAMSEMKVIVALTLLRFELLPDPTKVPIPLPRLVLKSKNGIYLYLKKL 508
>C13A8_CAEEL (Q27516) Putative cytochrome P450 CYP13A8 (EC 1.14.-.-)| Length = 509 Score = 97.4 bits (241), Expect = 3e-20 Identities = 58/169 (34%), Positives = 97/169 (57%), Gaps = 4/169 (2%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQ-RKAGSD 482 L+ +P+ Q KL++EV +EC ++ T D L+KL ++ + E+LRL+ S R+ + Sbjct: 336 LALNPKIQSKLQDEVDKECPNDEITFDQLSKLKYMDNVIKESLRLFPFASFANSRRCMRN 395 Query: 481 LEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSG 302 +G V G + I T+H DK VWG D EFKP R+++ + A LSF +G Sbjct: 396 TVIGEQIVEAGVDVMIDTWTLHHDKNVWGNDVEEFKPERWDSPLTPQ----QAYLSFGAG 451 Query: 301 PRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVHAPMDVI---TLRPK 164 PR C+G FA++E K +++ IL++++F + K P+ ++ T RP+ Sbjct: 452 PRVCLGMRFALLEQKGLLSHILKKYTFETNAK-TQLPIKLVGRATARPE 499
>CP4A5_RABIT (P14579) Cytochrome P450 4A5 precursor (EC 1.14.15.3) (CYPIVA5)| (Lauric acid omega-hydroxylase) Length = 511 Score = 96.3 bits (238), Expect = 7e-20 Identities = 61/178 (34%), Positives = 91/178 (51%), Gaps = 2/178 (1%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVP-TGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSD 482 L+THPE Q + REE+ G T + L+++ M + E +RLY PV I R S Sbjct: 338 LATHPEHQHRCREEIQGLLGDGASITWEHLDQMPYTTMCIKEAMRLYPPVPAISRDLSSP 397 Query: 481 LEV-GGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSS 305 + G +P+G +T+ I +H + VW + F P RF G AR H +A L FS Sbjct: 398 VTFPDGRSLPKGFTVTLSIYGLHHNPNVW-PNPEVFDPGRFTPGSAR---HSHAFLPFSG 453 Query: 304 GPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVHAPMDVITLRPKFGLPMILKSIE 131 G R+CIG+ FAM E K +A+ L RF P + P + L+ G+ + L+ ++ Sbjct: 454 GARNCIGKQFAMNELKVAVALTLVRFELLPDPTRIPKPTARLVLKSNNGIHLRLRKLQ 511
>CP341_MOUSE (Q9JMA7) Cytochrome P450 3A41 (EC 1.14.14.1)| Length = 504 Score = 95.9 bits (237), Expect = 9e-20 Identities = 52/147 (35%), Positives = 84/147 (57%), Gaps = 1/147 (0%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVP-TGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSD 482 L+THP+ Q+KL+EE+ ++ P T D + ++ ++M L ETLRLY + ++R D Sbjct: 322 LATHPDIQKKLQEEIDETLPNKAPPTYDTVMEMEYLDMVLNETLRLYPIGNRLERFCKKD 381 Query: 481 LEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSG 302 +E+ G+ +P+G+ + IP +H D + W E EF+P RF + P + F G Sbjct: 382 VELNGVYIPKGSTVMIPSYALHHDPQHWPE-PEEFQPERFSK-ENKGSIDPYLYMPFGIG 439 Query: 301 PRSCIGQSFAMIEAKAVIAVILQRFSF 221 PR+CIG FA + K + ++Q FSF Sbjct: 440 PRNCIGMRFAFMTMKLALTKVMQNFSF 466
>THAS_MOUSE (P36423) Thromboxane-A synthase (EC 5.3.99.5) (TXA synthase) (TXS)| (TS) Length = 533 Score = 95.9 bits (237), Expect = 9e-20 Identities = 58/153 (37%), Positives = 81/153 (52%), Gaps = 2/153 (1%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSE-VPTGDMLNK-LHLVNMFLLETLRLYAPVSLIQRKAGS 485 L+THP+ QE+L +EV G P L + L ++M + ETLR+Y P R+A Sbjct: 357 LATHPDCQERLLKEVDLFMGKHPAPEYHSLQEGLPYLDMVISETLRMYPPAFRFTREAAQ 416 Query: 484 DLEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSS 305 D EV G ++P GTVL I + +H D E W + F P RF AR + P L F + Sbjct: 417 DCEVLGQRIPAGTVLEIAVGALHHDPEHW-PNPETFDPERF-TAEARLQRRPFTYLPFGA 474 Query: 304 GPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPK 206 GPRSC+G ++ K I +L +F F SP+ Sbjct: 475 GPRSCLGVRLGLLVVKLTILQVLHKFRFEASPE 507
>CP3A5_HUMAN (P20815) Cytochrome P450 3A5 (EC 1.14.14.1) (CYPIIIA5) (P450-PCN3)| (HLp2) Length = 502 Score = 95.9 bits (237), Expect = 9e-20 Identities = 58/177 (32%), Positives = 99/177 (55%), Gaps = 4/177 (2%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVP-TGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSD 482 L+THP+ Q+KL++E+ ++ P T D + ++ ++M + ETLRL+ ++R D Sbjct: 321 LATHPDVQQKLQKEIDAVLPNKAPPTYDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKD 380 Query: 481 LEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSG 302 +E+ G+ +P+G+++ IP +H D + W E EF+P RF + P F +G Sbjct: 381 VEINGVFIPKGSMVVIPTYALHHDPKYWTE-PEEFRPERFSK--KKDSIDPYIYTPFGTG 437 Query: 301 PRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVHAPMDVIT---LRPKFGLPMILK 140 PR+CIG FA++ K + +LQ FSF K P+ + T L+P+ P++LK Sbjct: 438 PRNCIGMRFALMNMKLALIRVLQNFSFK-PCKETQIPLKLDTQGLLQPE--KPIVLK 491
>CP4C3_DROME (Q9VA27) Cytochrome P450 4c3 (EC 1.14.-.-) (CYPIVC3)| Length = 535 Score = 95.5 bits (236), Expect = 1e-19 Identities = 61/174 (35%), Positives = 97/174 (55%), Gaps = 6/174 (3%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTGDMLNKL---HLVNMFLLETLRLYAPVSLIQRKAG 488 L HPE+QE++ EE+ G + T + L + + ++LRL+ V ++ R G Sbjct: 358 LGCHPEYQERVVEELDSIFGDDKETPATMKNLMDMRYLECCIKDSLRLFPSVPMMARMVG 417 Query: 487 SDLEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRF--ENGVARAGKHPNALLS 314 D+ +GG VP GT I +HR+ V+ + +F P F EN AG+HP A + Sbjct: 418 EDVNIGGKIVPAGTQAIIMTYALHRNPRVFPKP-EQFNPDNFLPENC---AGRHPFAYIP 473 Query: 313 FSSGPRSCIGQSFAMIEAKAVIAVILQRFSF-SLSPKYVHAPMDVITLRPKFGL 155 FS+GPR+CIGQ FA++E KAVI+ +L+++ ++ + + + LRPK GL Sbjct: 474 FSAGPRNCIGQKFAILEEKAVISTVLRKYKIEAVDRREDLTLLGELILRPKDGL 527
>CP4F6_RAT (P51871) Cytochrome P450 4F6 (EC 1.14.14.1) (CYPIVF6)| Length = 537 Score = 95.5 bits (236), Expect = 1e-19 Identities = 61/150 (40%), Positives = 86/150 (57%), Gaps = 6/150 (4%) Frame = -1 Query: 658 LSTHPEWQEKLREEV---LRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAG 488 L+ HPE+QE+ R+EV LR+ E D L +L + M + E+LRL+ PV LI R Sbjct: 344 LARHPEYQERCRQEVRELLRDREPEEIEWDDLAQLPFLTMCIKESLRLHPPVLLISRCCS 403 Query: 487 SDLEV-GGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRF--ENGVARAGKHPNALL 317 D+ + G +P+G + I I +H + VW D + P RF EN R+ P A + Sbjct: 404 QDIVLPDGRVIPKGNICVISIFGVHHNPSVW-PDPEVYNPFRFDPENPQKRS---PLAFI 459 Query: 316 SFSSGPRSCIGQSFAMIEAKAVIAVILQRF 227 FS+GPR+CIGQ+FAM E K +A+ L RF Sbjct: 460 PFSAGPRNCIGQTFAMSEIKVALALTLLRF 489
>CPXB_BACME (P14779) Bifunctional P-450:NADPH-P450 reductase (Cytochrome| P450(BM-3)) (P450BM-3) [Includes: Cytochrome P450 102 (EC 1.14.14.1); NADPH--cytochrome P450 reductase (EC 1.6.2.4)] Length = 1048 Score = 94.7 bits (234), Expect = 2e-19 Identities = 58/166 (34%), Positives = 84/166 (50%), Gaps = 1/166 (0%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSDL 479 L +P +K EE R VP+ + +L V M L E LRL+ A D Sbjct: 280 LVKNPHVLQKAAEEAARVLVDPVPSYKQVKQLKYVGMVLNEALRLWPTAPAFSLYAKEDT 339 Query: 478 EVGG-IKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSG 302 +GG + +G L + I +HRDK +WG+D EF+P RFEN A +A F +G Sbjct: 340 VLGGEYPLEKGDELMVLIPQLHRDKTIWGDDVEEFRPERFENPSAIP---QHAFKPFGNG 396 Query: 301 PRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVHAPMDVITLRPK 164 R+CIGQ FA+ EA V+ ++L+ F F Y + +TL+P+ Sbjct: 397 QRACIGQQFALHEATLVLGMMLKHFDFEDHTNYELDIKETLTLKPE 442
>CP4F5_RAT (P51870) Cytochrome P450 4F5 (EC 1.14.14.1) (CYPIVF5)| Length = 526 Score = 94.7 bits (234), Expect = 2e-19 Identities = 64/172 (37%), Positives = 95/172 (55%), Gaps = 4/172 (2%) Frame = -1 Query: 658 LSTHPEWQEKLREEV---LRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAG 488 L+ HPE+QE+ R+EV LR+ E D L +L + M + E+LRL+ P + R+ Sbjct: 346 LARHPEYQERCRQEVWELLRDREPEEIEWDDLAQLPFLTMCIKESLRLHPPAIDLLRRCT 405 Query: 487 SDLEV-GGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSF 311 D+ + G +P+G + I I IH + VW D F P RF++ R + P + + F Sbjct: 406 QDIVLPDGRVIPKGNICVISIFGIHHNPSVW-PDPEVFDPFRFDSE-NRQKRSPLSFIPF 463 Query: 310 SSGPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVHAPMDVITLRPKFGL 155 S+GPR+CIGQ+FAM E K V+A+ L RF K ++I LR + GL Sbjct: 464 SAGPRNCIGQTFAMNEMKVVVALTLLRFRVLPDDKEPRRKPEII-LRAEGGL 514
>CP4A4_RABIT (P10611) Cytochrome P450 4A4 precursor (EC 1.14.14.1) (CYPIVA4)| (Prostaglandin omega-hydroxylase) (P450-P-2) Length = 510 Score = 94.4 bits (233), Expect = 3e-19 Identities = 59/177 (33%), Positives = 92/177 (51%), Gaps = 2/177 (1%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVP-TGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSD 482 L+THPE Q + REE+ G T + L+++ M + E LRLY PV + R+ Sbjct: 337 LATHPEHQHRCREEIQGLLGDGASITWEHLDQMPYTTMCIKEALRLYPPVPSVTRQLSKP 396 Query: 481 LEV-GGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSS 305 + G +P+G +L + I +H + +VW ++ F P RF A H +A L FS Sbjct: 397 VTFPDGRSLPKGVILFLSIYGLHYNPKVW-QNPEVFDPFRFAPDSAY---HSHAFLPFSG 452 Query: 304 GPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVHAPMDVITLRPKFGLPMILKSI 134 G R+CIG+ FAM E K +A+ L RF P + P+ + L+ K G+ + L+ + Sbjct: 453 GARNCIGKQFAMRELKVAVALTLVRFELLPDPTRIPIPIARVVLKSKNGIHLRLRKL 509
>CP3A3_HUMAN (P05184) Cytochrome P450 3A3 (EC 1.14.14.1) (CYPIIIA3) (HLp)| Length = 503 Score = 94.4 bits (233), Expect = 3e-19 Identities = 53/147 (36%), Positives = 84/147 (57%), Gaps = 1/147 (0%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVP-TGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSD 482 L+THP+ Q+KL+EE+ ++ P T D + ++ ++M + ETLRL+ ++R D Sbjct: 321 LATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKD 380 Query: 481 LEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSG 302 +E+ G+ +P+G V+ IP +HRD + W E +F P RF + P F SG Sbjct: 381 VEINGMFIPKGWVVMIPSYALHRDPKYWTE-PEKFLPERFSK-KNKDNIDPYIYTPFGSG 438 Query: 301 PRSCIGQSFAMIEAKAVIAVILQRFSF 221 PR+CIG FA++ K + +LQ FSF Sbjct: 439 PRNCIGMRFALMNMKLALIRVLQNFSF 465
>CP3A4_HUMAN (P08684) Cytochrome P450 3A4 (EC 1.14.13.67) (Quinine| 3-monooxygenase) (CYPIIIA4) (Nifedipine oxidase) (Taurochenodeoxycholate 6-alpha-hydroxylase) (EC 1.14.13.97) (NF-25) (P450-PCN1) Length = 502 Score = 94.4 bits (233), Expect = 3e-19 Identities = 53/147 (36%), Positives = 84/147 (57%), Gaps = 1/147 (0%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVP-TGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSD 482 L+THP+ Q+KL+EE+ ++ P T D + ++ ++M + ETLRL+ ++R D Sbjct: 320 LATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKD 379 Query: 481 LEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSG 302 +E+ G+ +P+G V+ IP +HRD + W E +F P RF + P F SG Sbjct: 380 VEINGMFIPKGWVVMIPSYALHRDPKYWTE-PEKFLPERFSK-KNKDNIDPYIYTPFGSG 437 Query: 301 PRSCIGQSFAMIEAKAVIAVILQRFSF 221 PR+CIG FA++ K + +LQ FSF Sbjct: 438 PRNCIGMRFALMNMKLALIRVLQNFSF 464
>CP4V2_HUMAN (Q6ZWL3) Cytochrome P450 4V2 (EC 1.14.-.-)| Length = 525 Score = 94.0 bits (232), Expect = 4e-19 Identities = 65/176 (36%), Positives = 98/176 (55%), Gaps = 3/176 (1%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECG-SEVP-TGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGS 485 L ++PE Q+K+ E+ G S+ P T + L KL + + ETLRL+ V L R Sbjct: 345 LGSNPEVQKKVDHELDDVFGKSDRPATVEDLKKLRYLECVIKETLRLFPSVPLFARSVSE 404 Query: 484 DLEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSS 305 D EV G +V +GT I +HRD + + EF+P RF A+ G+HP A + FS+ Sbjct: 405 DCEVAGYRVLKGTEAVIIPYALHRDPRYF-PNPEEFQPERFFPENAQ-GRHPYAYVPFSA 462 Query: 304 GPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVHAPMD-VITLRPKFGLPMILK 140 GPR+CIGQ FA++E K +++ IL+ F + K ++ + LRP G+ + LK Sbjct: 463 GPRNCIGQKFAVMEEKTILSCILRHFWIESNQKREELGLEGQLILRPSNGIWIKLK 518
>CYPE_BACSU (O08336) Probable bifunctional P-450:NADPH-P450 reductase 2| [Includes: Cytochrome P450 102 (EC 1.14.14.1); NADPH--cytochrome P450 reductase (EC 1.6.2.4)] Length = 1054 Score = 94.0 bits (232), Expect = 4e-19 Identities = 55/165 (33%), Positives = 84/165 (50%), Gaps = 1/165 (0%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSDL 479 L THPE +K +EE R + P + +L + M L ETLRLY A D Sbjct: 283 LLTHPEKLKKAQEEADRVLTDDTPEYKQIQQLKYIRMVLNETLRLYPTAPAFSLYAKEDT 342 Query: 478 EVGG-IKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSG 302 +GG + +G +T+ I +HRD+ WG DA +F+P RFE+ + +A F +G Sbjct: 343 VLGGEYPISKGQPVTVLIPKLHRDQNAWGPDAEDFRPERFED---PSSIPHHAYKPFGNG 399 Query: 301 PRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVHAPMDVITLRP 167 R+CIG FA+ EA V+ ++L+ F Y + +T++P Sbjct: 400 QRACIGMQFALQEATMVLGLVLKHFELINHTGYELKIKEALTIKP 444
>C13A2_CAEEL (Q27518) Putative cytochrome P450 CYP13A2 (EC 1.14.-.-)| Length = 515 Score = 94.0 bits (232), Expect = 4e-19 Identities = 52/152 (34%), Positives = 81/152 (53%), Gaps = 1/152 (0%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQ-RKAGSD 482 L+ +P+ QEK+ EE+ RE G+ + L +L ++ + E LRLY S+ RK Sbjct: 339 LAVNPKIQEKVIEEIAREFGTSEVEFEKLGRLKYMDCVIKEALRLYPLASISNSRKCMKT 398 Query: 481 LEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSG 302 V G+K+ G + + ++H D E+WGED EFKP R+ +H A L F G Sbjct: 399 TTVNGVKIEAGVYVQMDTWSLHYDPELWGEDVKEFKPERWSTD--EPLEHKGAYLPFGLG 456 Query: 301 PRSCIGQSFAMIEAKAVIAVILQRFSFSLSPK 206 PR CIG A++E K ++ +L+ ++F K Sbjct: 457 PRQCIGMRLAIMEQKILLTHLLKNYTFETGNK 488
>CP3AA_MESAU (Q64148) Cytochrome P450 3A10 (EC 1.14.13.94) (CYPIIIA10)| (Lithocholate 6-beta-hydroxylase) (6 beta-hydroxylase) Length = 503 Score = 93.6 bits (231), Expect = 5e-19 Identities = 49/146 (33%), Positives = 83/146 (56%), Gaps = 1/146 (0%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVP-TGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSD 482 L+THP+ Q+KL +E+ ++ P T D+L + ++M + E LRLY + ++R + Sbjct: 321 LATHPDVQKKLHDEIDSALPNKAPVTYDVLMGMEYLDMVINEGLRLYPIANRLERISKKA 380 Query: 481 LEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSG 302 +E+ G+ +P+G + +P +HRD E W E EF+P RF + P + F +G Sbjct: 381 VEINGLFIPKGITVMVPTYPLHRDPEYWPE-PEEFRPERFSK-ENKGSIDPYVYMPFGNG 438 Query: 301 PRSCIGQSFAMIEAKAVIAVILQRFS 224 PR+CIG FA++ K + +LQ F+ Sbjct: 439 PRNCIGMRFALLSMKLAVVSVLQNFT 464
>CP3A8_MACFA (P33268) Cytochrome P450 3A8 (EC 1.14.14.1) (CYPIIIA8) (P450-MKNF2)| (P-450-MK2) Length = 503 Score = 93.6 bits (231), Expect = 5e-19 Identities = 53/147 (36%), Positives = 82/147 (55%), Gaps = 1/147 (0%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVP-TGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSD 482 L+THP+ Q+KL+EE+ ++ P T D + ++ ++M + ETLR++ ++R D Sbjct: 321 LATHPDVQQKLQEEIDTVLPNKAPPTYDTVLQMEYLDMVVNETLRIFPIAMRLERVCKKD 380 Query: 481 LEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSG 302 +E+ GI +P+G V+ IP +H D + W E +F P RF P F SG Sbjct: 381 VEINGIFIPKGVVVMIPSYALHHDPKYWPE-PEKFLPERFSK-KNNDNIDPYIYTPFGSG 438 Query: 301 PRSCIGQSFAMIEAKAVIAVILQRFSF 221 PR+CIG FA++ K I +LQ FSF Sbjct: 439 PRNCIGMRFALMNMKLAIIRVLQNFSF 465
>CP343_HUMAN (Q9HB55) Cytochrome P450 3A43 (EC 1.14.14.1)| Length = 503 Score = 93.6 bits (231), Expect = 5e-19 Identities = 53/152 (34%), Positives = 86/152 (56%), Gaps = 6/152 (3%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVP-TGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSD 482 L+THP+ Q+KL+EE+ ++ P T D L ++ ++M + ETLRL+ VS + R D Sbjct: 321 LATHPDVQQKLQEEIDAVLPNKAPVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKD 380 Query: 481 LEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNAL-----L 317 +E+ G+ +P+G + +PI +H D + W E +F P RF K+ +++ + Sbjct: 381 IEINGVFIPKGLAVMVPIYALHHDPKYWTE-PEKFCPERFSK------KNKDSIDLYRYI 433 Query: 316 SFSSGPRSCIGQSFAMIEAKAVIAVILQRFSF 221 F +GPR+CIG FA+ K + LQ FSF Sbjct: 434 PFGAGPRNCIGMRFALTNIKLAVIRALQNFSF 465
>CP4CU_BLAGE (Q964T1) Cytochrome P450 4c21 (EC 1.14.14.1) (CYPIVC21)| Length = 501 Score = 93.6 bits (231), Expect = 5e-19 Identities = 54/152 (35%), Positives = 85/152 (55%), Gaps = 6/152 (3%) Frame = -1 Query: 658 LSTHPEWQEKLREEV--LRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGS 485 L HPE QE+ +EV + + VPT LN ++ + + E+LRL+ V R+A Sbjct: 325 LGHHPEIQEEAYKEVQDIFQGSDRVPTMADLNNMNYLERVIKESLRLHPSVIYFVREAHQ 384 Query: 484 DLEVGGIKVPEGTVLTIPIATIHRDKEVWGE----DANEFKPMRFENGVARAGKHPNALL 317 D E+GG +P GT + + IHR+ E++ + + F P R N +HP A + Sbjct: 385 DFELGGYTIPAGTNIDFSVPFIHRNPEIFPNPRCFNPDNFLPDRVVN------RHPYAYI 438 Query: 316 SFSSGPRSCIGQSFAMIEAKAVIAVILQRFSF 221 FS+GPR+CIGQ FA++E K V++ +L+ + F Sbjct: 439 PFSAGPRNCIGQRFALLEEKVVLSYLLRHYRF 470
>CP4V2_PONPY (Q5RCN6) Cytochrome P450 4V2 (EC 1.14.-.-)| Length = 525 Score = 93.6 bits (231), Expect = 5e-19 Identities = 65/176 (36%), Positives = 97/176 (55%), Gaps = 3/176 (1%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECG-SEVP-TGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGS 485 L +PE Q+K+ E+ G S+ P T + L KL + + ETLRL+ V L R Sbjct: 345 LGCNPEVQQKVDHELDDVFGKSDRPATVEDLKKLRYLECVIKETLRLFPSVPLFARSVSE 404 Query: 484 DLEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSS 305 D EV G +V +GT I +HRD + + EF+P RF A+ G+HP A + FS+ Sbjct: 405 DCEVAGYRVLKGTEAVIIPYALHRDPRYF-PNPEEFQPERFFPENAQ-GRHPYAYVPFSA 462 Query: 304 GPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVHAPMD-VITLRPKFGLPMILK 140 GPR+CIGQ FA++E K +++ IL+ F + K ++ + LRP G+ + LK Sbjct: 463 GPRNCIGQKFAVMEEKTILSCILRHFWIESNQKREELGLEGQLILRPSNGIWIKLK 518
>CP4F4_RAT (P51869) Cytochrome P450 4F4 (EC 1.14.14.1) (CYPIVF4)| Length = 522 Score = 93.2 bits (230), Expect = 6e-19 Identities = 57/148 (38%), Positives = 86/148 (58%), Gaps = 4/148 (2%) Frame = -1 Query: 658 LSTHPEWQEKLREEV---LRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAG 488 L+ HPE+QE+ R+EV LR+ S D L +L + M + E+LRL+ PV++I R+ Sbjct: 344 LARHPEYQERCRQEVRELLRDRESTEIEWDDLAQLPFLTMCIKESLRLHPPVTVISRRCT 403 Query: 487 SDLEV-GGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSF 311 D+ + G +P+G + I I H + VW D + P RF+ + + P A + F Sbjct: 404 QDIVLPDGRVIPKGVICIINIFATHHNPTVW-PDPEVYDPFRFDPENIK-DRSPLAFIPF 461 Query: 310 SSGPRSCIGQSFAMIEAKAVIAVILQRF 227 S+GPR+CIGQ+FAM E K +A+ L RF Sbjct: 462 SAGPRNCIGQTFAMNEMKVALALTLLRF 489
>CP4AB_HUMAN (Q02928) Cytochrome P450 4A11 precursor (EC 1.14.15.3) (CYPIVA11)| (Fatty acid omega-hydroxylase) (P-450 HK omega) (Lauric acid omega-hydroxylase) (CYP4AII) (P450-HL-omega) Length = 519 Score = 93.2 bits (230), Expect = 6e-19 Identities = 60/177 (33%), Positives = 94/177 (53%), Gaps = 2/177 (1%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVP-TGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSD 482 L+THP+ QE+ REE+ G T + L+++ M + E LRLY PV I R+ + Sbjct: 337 LATHPKHQERCREEIHSLLGDGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTP 396 Query: 481 LEV-GGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSS 305 + G +P+G ++ + I +H + +VW + F P RF G A+ H +A L FS Sbjct: 397 VTFPDGRSLPKGIMVLLSIYGLHHNPKVW-PNPEVFDPFRFAPGSAQ---HSHAFLPFSG 452 Query: 304 GPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVHAPMDVITLRPKFGLPMILKSI 134 G R+CIG+ FAM E K A+ L RF P + P+ + L+ K G+ + L+ + Sbjct: 453 GSRNCIGKQFAMNELKVATALTLLRFELLPDPTRIPIPIARLVLKSKNGIHLRLRRL 509
>CP3AL_CALJA (O18993) Cytochrome P450 3A21 (EC 1.14.14.1) (CYPIIIA21) (P450| CM3A-10) Length = 503 Score = 92.8 bits (229), Expect = 8e-19 Identities = 51/147 (34%), Positives = 83/147 (56%), Gaps = 1/147 (0%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVP-TGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSD 482 L+THP+ Q+KL+EE+ ++ P T D + ++ ++M + ETLRL+ ++R D Sbjct: 321 LATHPDVQQKLQEEIDAVLPNKAPATYDTVLQMEYLDMVVNETLRLFPLAMRLERVCKKD 380 Query: 481 LEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSG 302 +E+ G+ +P+G V+ IP +H D + W E +F P RF + P F +G Sbjct: 381 VEINGVFIPKGVVVMIPSYALHYDPKYWTE-PEKFLPERFSKN-NKDNIDPYIYTPFGTG 438 Query: 301 PRSCIGQSFAMIEAKAVIAVILQRFSF 221 PR+CIG FA++ K + +LQ FSF Sbjct: 439 PRNCIGMRFALMNMKLALIRVLQNFSF 465
>CP3A7_HUMAN (P24462) Cytochrome P450 3A7 (EC 1.14.14.1) (CYPIIIA7) (P450-HFLA)| Length = 503 Score = 92.8 bits (229), Expect = 8e-19 Identities = 51/147 (34%), Positives = 83/147 (56%), Gaps = 1/147 (0%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVP-TGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSD 482 L+THP+ Q+K+++E+ ++ P T D + +L ++M + ETLRL+ ++R D Sbjct: 321 LATHPDVQQKVQKEIDTVLPNKAPPTYDTVLQLEYLDMVVNETLRLFPVAMRLERVCKKD 380 Query: 481 LEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSG 302 +E+ G+ +P+G V+ IP +H D + W E +F P RF + P F SG Sbjct: 381 VEINGMFIPKGVVVMIPSYVLHHDPKYWRE-PEKFLPERFSK-KNKDNIDPYIYTPFGSG 438 Query: 301 PRSCIGQSFAMIEAKAVIAVILQRFSF 221 PR+CIG FA++ K + +LQ FSF Sbjct: 439 PRNCIGMRFALVNMKLALVRVLQNFSF 465
>CP4FC_HUMAN (Q9HCS2) Cytochrome P450 4F12 (EC 1.14.14.1) (CYPIVF12)| Length = 524 Score = 92.8 bits (229), Expect = 8e-19 Identities = 56/150 (37%), Positives = 86/150 (57%), Gaps = 4/150 (2%) Frame = -1 Query: 658 LSTHPEWQEKLREEV---LRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAG 488 L+ HPE+QE+ R+EV L++ + D L +L + M + E+LRL+ P I R Sbjct: 344 LARHPEYQERCRQEVQELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCT 403 Query: 487 SDLEV-GGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSF 311 D+ + G +P+G I I +H + VW D + P RF+ ++ G+ P A + F Sbjct: 404 QDIVLPDGRVIPKGITCLIDIIGVHHNPTVW-PDPEVYDPFRFDPENSK-GRSPLAFIPF 461 Query: 310 SSGPRSCIGQSFAMIEAKAVIAVILQRFSF 221 S+GPR+CIGQ+FAM E K V+A++L F F Sbjct: 462 SAGPRNCIGQAFAMAEMKVVLALMLLHFRF 491
>CP4AC_MOUSE (Q91WL5) Cytochrome P450 4A12 (EC 1.14.14.1) (CYPIVA12)| Length = 508 Score = 92.8 bits (229), Expect = 8e-19 Identities = 59/178 (33%), Positives = 93/178 (52%), Gaps = 2/178 (1%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVP-TGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSD 482 L+T+PE Q++ R+E+ G T + L+K+ M + E LR+Y PV + R+ S Sbjct: 335 LATNPEHQQRCRKEIQSLLGDGTSITWNDLDKMPYTTMCIKEALRIYPPVPSVSRELSSP 394 Query: 481 LEV-GGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSS 305 + G +P+G + + +H + VW + F P RF G +R H ++ L FS Sbjct: 395 VTFPDGRSLPKGIHVMLSFYGLHHNPTVW-PNPEVFDPSRFAPGSSR---HSHSFLPFSG 450 Query: 304 GPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVHAPMDVITLRPKFGLPMILKSIE 131 G R+CIG+ FAM E K +A+ L RF P V P+ I L+ K G+ + LK ++ Sbjct: 451 GARNCIGKQFAMNELKVAVALTLLRFELLPDPTRVPIPIPRIVLKSKNGIHLHLKKLQ 508
>CP4F8_HUMAN (P98187) Cytochrome P450 4F8 (EC 1.14.14.1) (CYPIVF8)| Length = 520 Score = 92.0 bits (227), Expect = 1e-18 Identities = 58/148 (39%), Positives = 84/148 (56%), Gaps = 4/148 (2%) Frame = -1 Query: 658 LSTHPEWQEKLREEV---LRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAG 488 L+ HPE+QE+ R+EV L++ + D L +L + M L E+LRL+ P+ R Sbjct: 344 LARHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPFLTMCLKESLRLHPPIPTFARGCT 403 Query: 487 SDLEVGGIKV-PEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSF 311 D+ + +V P+G V I I IH + VW D + P RF+ A+ + P A + F Sbjct: 404 QDVVLPDSRVIPKGNVCNINIFAIHHNPSVW-PDPEVYDPFRFDPENAQK-RSPMAFIPF 461 Query: 310 SSGPRSCIGQSFAMIEAKAVIAVILQRF 227 S+GPR+CIGQ FAM E K V+A+ L RF Sbjct: 462 SAGPRNCIGQKFAMAEMKVVLALTLLRF 489
>CP132_MYCTU (P77900) Putative cytochrome P450 132 (EC 1.14.-.-)| Length = 461 Score = 92.0 bits (227), Expect = 1e-18 Identities = 60/172 (34%), Positives = 91/172 (52%), Gaps = 1/172 (0%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSDL 479 ++ +P+ ++ + E+ G PT D L KL L E+ R ++ V +I R+A D Sbjct: 290 MALNPQARDHMLTELDDVLGMRRPTADDLGKLAWTTACLQESQRYFSSVWIIAREAVDDD 349 Query: 478 EVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSGP 299 + G ++ GT + IPI IH D W D + F P RF + A L F G Sbjct: 350 IIDGHRIRRGTTVVIPIHHIHHDPR-WWPDPDRFDPGRFLR--CPTDRPRCAYLPFGGGR 406 Query: 298 RSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVHAPMD-VITLRPKFGLPMI 146 R CIGQSFA++E + A++ Q F+F L+P Y H ++ +TLRPK G+ +I Sbjct: 407 RICIGQSFALMEMVLMAAIMSQHFTFDLAPGY-HVELEATLTLRPKHGVHVI 457
>CP132_MYCBO (P59954) Putative cytochrome P450 132 (EC 1.14.-.-)| Length = 461 Score = 92.0 bits (227), Expect = 1e-18 Identities = 60/172 (34%), Positives = 91/172 (52%), Gaps = 1/172 (0%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSDL 479 ++ +P+ ++ + E+ G PT D L KL L E+ R ++ V +I R+A D Sbjct: 290 MALNPQARDHMLTELDDVLGMRRPTADDLGKLAWTTACLQESQRYFSSVWIIAREAVDDD 349 Query: 478 EVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSGP 299 + G ++ GT + IPI IH D W D + F P RF + A L F G Sbjct: 350 IIDGHRIRRGTTVVIPIHHIHHDPR-WWPDPDRFDPGRFLR--CPTDRPRCAYLPFGGGR 406 Query: 298 RSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVHAPMD-VITLRPKFGLPMI 146 R CIGQSFA++E + A++ Q F+F L+P Y H ++ +TLRPK G+ +I Sbjct: 407 RICIGQSFALMEMVLMAAIMSQHFTFDLAPGY-HVELEATLTLRPKHGVHVI 457
>CP4FE_MOUSE (Q9EP75) Cytochrome P450 4F14 (EC 1.14.13.30) (Leukotriene-B4| omega-hydroxylase) (Leukotriene-B4 20-monooxygenase) (Cytochrome P450-LTB-omega) (Cyp4f-14) Length = 524 Score = 91.7 bits (226), Expect = 2e-18 Identities = 64/172 (37%), Positives = 93/172 (54%), Gaps = 4/172 (2%) Frame = -1 Query: 658 LSTHPEWQEKLREEV---LRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAG 488 L+ HPE+QE+ R+EV LR E D L +L + M + E+LRL+ PV++I R Sbjct: 344 LARHPEYQERCRQEVQELLRGREPEEIEWDDLAQLPFLTMCIKESLRLHPPVTVISRCCT 403 Query: 487 SDLEV-GGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSF 311 D+ + G +P+G + I I IH + VW D + P RF+ + P A + F Sbjct: 404 QDILLPDGRTIPKGIICLISIFGIHHNPSVW-PDPEVYDPFRFDPENIKDSS-PLAFIPF 461 Query: 310 SSGPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVHAPMDVITLRPKFGL 155 S+GPR+CIGQ+FAM E K +A+ L RF K ++I LR + GL Sbjct: 462 SAGPRNCIGQTFAMSEMKVALALTLLRFRLLPDDKEPRRQPELI-LRAEGGL 512
>C356_FUNHE (Q8AXY5) Cytochrome P450 3A56 (EC 1.14.14.1) (CYPIIIA56)| Length = 496 Score = 91.3 bits (225), Expect = 2e-18 Identities = 52/149 (34%), Positives = 86/149 (57%), Gaps = 1/149 (0%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTG-DMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSD 482 L+T+PE +KL+EE+ ++ P L ++ ++ + E+LRL+ + ++R A + Sbjct: 320 LATNPEVMKKLQEEIDATFPNKAPVHYQPLMEMEYLDCVINESLRLFPIAARLERVAKAA 379 Query: 481 LEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSG 302 +E+ GI +P+ V+ IP +HRD E+W E FKP RF + P + F SG Sbjct: 380 VEINGIVIPKDMVVMIPTWPLHRDPEIWPE-PEAFKPERFSK-KNKDNIDPYIYMPFGSG 437 Query: 301 PRSCIGQSFAMIEAKAVIAVILQRFSFSL 215 PR+CIG FA++ K + ILQ++SFS+ Sbjct: 438 PRNCIGMRFALVLIKLAVVEILQQYSFSV 466
>CP4F1_RAT (P33274) Cytochrome P450 4F1 (EC 1.14.14.1) (CYPIVF1) (P450-A3)| Length = 524 Score = 90.9 bits (224), Expect = 3e-18 Identities = 63/172 (36%), Positives = 93/172 (54%), Gaps = 4/172 (2%) Frame = -1 Query: 658 LSTHPEWQEKLREEV---LRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAG 488 L+ PE+QE+ R+EV LR+ E D L +L + M + E+LRL+ PV++I R Sbjct: 344 LANDPEYQERCRQEVQELLRDRDPEEIEWDDLAQLPFLTMCIKESLRLHPPVTVISRCCT 403 Query: 487 SDLEV-GGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSF 311 D+ + G +P+G + I I IH + VW D + P RF+ + P A + F Sbjct: 404 QDILLPDGRTIPKGIICLISIFGIHHNPSVW-PDPEVYNPFRFDPENIKDSS-PLAFIPF 461 Query: 310 SSGPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVHAPMDVITLRPKFGL 155 S+GPR+CIGQ+FAM E K +A+ L RF K ++I LR + GL Sbjct: 462 SAGPRNCIGQTFAMSEMKVALALTLLRFRLLPDDKEPRRQPELI-LRAEGGL 512
>CP131_DROME (Q9VFJ0) Probable cytochrome P450 313a1 (EC 1.14.-.-)| (CYPCCCXIIIA1) Length = 492 Score = 90.9 bits (224), Expect = 3e-18 Identities = 56/158 (35%), Positives = 84/158 (53%), Gaps = 6/158 (3%) Frame = -1 Query: 658 LSTHPEWQEKLREE---VLRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAG 488 L+ HPE QE + EE V + G T + KL + + ETLRL + + R+ Sbjct: 313 LANHPEHQEAVFEELNGVFPDAGHFGITYPDMQKLDYLERVIKETLRLIPAIPITARETK 372 Query: 487 SDLEVG-GIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRF--ENGVARAGKHPNALL 317 +D+ + G+ +P+G V+ I + HR+ EVWG DA+ F P F EN KHP A + Sbjct: 373 NDVRLSNGVLIPKGVVIGIDMFHTHRNPEVWGPDADNFNPDNFLAEN---MEQKHPYAYI 429 Query: 316 SFSSGPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKY 203 F+ G R+CIG +AM+ +K + IL+ + S S Y Sbjct: 430 PFARGKRNCIGSKYAMMSSKFALCRILRNYKISTSTLY 467
>C330_FUNHE (Q9PVE8) Cytochrome P450 3A30 (EC 1.14.14.1) (CYPIIIA30)| Length = 496 Score = 90.9 bits (224), Expect = 3e-18 Identities = 51/149 (34%), Positives = 86/149 (57%), Gaps = 1/149 (0%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTG-DMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSD 482 L+T+PE +KL+EE+ ++ P L ++ ++ + E+LRL+ + ++R A + Sbjct: 320 LATNPEVMKKLQEEIDATFPNKAPVHYQPLMEMEYLDCVINESLRLFPIAARLERVAKAA 379 Query: 481 LEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSG 302 +E+ G+ +P+ V+ IP +HRD E+W E FKP RF + P + F SG Sbjct: 380 VEINGVVIPKDMVVMIPTWPLHRDPEIWPE-PEAFKPERFSK-KNKDNIDPYIYMPFGSG 437 Query: 301 PRSCIGQSFAMIEAKAVIAVILQRFSFSL 215 PR+CIG FA++ K + ILQ++SFS+ Sbjct: 438 PRNCIGMRFALVLIKLAVVEILQQYSFSV 466
>CP4X1_HUMAN (Q8N118) Cytochrome P450 4X1 (EC 1.14.14.1) (CYPIVX1)| Length = 509 Score = 90.9 bits (224), Expect = 3e-18 Identities = 67/180 (37%), Positives = 92/180 (51%), Gaps = 5/180 (2%) Frame = -1 Query: 658 LSTHPEWQEKLREEV--LRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGS 485 L+ +PE QE+ REEV + GS + T D L ++ M + ET RL V I R Sbjct: 332 LALNPEHQERCREEVRGILGDGSSI-TWDQLGEMSYTTMCIKETCRLIPAVPSISRDLSK 390 Query: 484 DLEV-GGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRF--ENGVARAGKHPNALLS 314 L G +P G + + I +H + VW ++ F P+RF EN R HP A L Sbjct: 391 PLTFPDGCTLPAGITVVLSIWGLHHNPAVW-KNPKVFDPLRFSQENSDQR---HPYAYLP 446 Query: 313 FSSGPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVHAPMDVITLRPKFGLPMILKSI 134 FS+G R+CIGQ FAMIE K IA+IL F + P + L+PK G+ + LK + Sbjct: 447 FSAGSRNCIGQEFAMIELKVTIALILLHFRVTPDPTRPLTFPNHFILKPKNGMYLHLKKL 506
>CP3AR_ONCMY (O42563) Cytochrome P450 3A27 (EC 1.14.14.1) (CYPIIIA27)| Length = 518 Score = 90.5 bits (223), Expect = 4e-18 Identities = 52/149 (34%), Positives = 83/149 (55%), Gaps = 1/149 (0%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTG-DMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSD 482 L+T+ KL+EE+ ++ P + L ++ ++ L E+LRLY ++R A Sbjct: 326 LATNHHVMTKLQEEIDTVFPNKAPIQYEALMQMDYLDCVLNESLRLYPIAPRLERVAKKT 385 Query: 481 LEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSG 302 +E+ GI +P+ ++ +P T+HRD E+W D EFKP RF + P + F +G Sbjct: 386 VEINGIVIPKDCIVLVPTWTLHRDPEIW-SDPEEFKPERFSK-ENKESIDPYTYMPFGAG 443 Query: 301 PRSCIGQSFAMIEAKAVIAVILQRFSFSL 215 PR+CIG FA+I K + ILQ F+FS+ Sbjct: 444 PRNCIGMRFALIMIKLAMVEILQSFTFSV 472
>CP4AC_RAT (P24464) Cytochrome P450 4A12 (EC 1.14.14.1) (CYPIVA12) (CYPIVA8)| (P450-KP1) (P450-PP1) Length = 508 Score = 90.1 bits (222), Expect = 5e-18 Identities = 55/178 (30%), Positives = 91/178 (51%), Gaps = 2/178 (1%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVP-TGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSD 482 L+T+PE Q+ R+E+ G T D L+K+ M + E LR+Y PV+ + R + Sbjct: 335 LATNPEHQQGCRKEIQSLLGDGASITWDDLDKMPYTTMCIKEALRIYPPVTAVSRMLSTP 394 Query: 481 LEV-GGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSS 305 + G +P+G + + +H + VW + F P RF + +H ++ L FS Sbjct: 395 VTFPDGRSLPKGITVMLSFYGLHHNPTVW-PNPEVFDPYRF---APESSRHSHSFLPFSG 450 Query: 304 GPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVHAPMDVITLRPKFGLPMILKSIE 131 G R+CIG+ FAM E K +A+ L RF P + P+ + L+ K G+ + LK ++ Sbjct: 451 GARNCIGKQFAMNELKVAVALTLLRFELLPDPTRIPIPIPRLVLKSKNGIYLRLKKLQ 508
>CP4Z1_HUMAN (Q86W10) Cytochrome P450 4Z1 (EC 1.14.14.1) (CYPIVZ1)| Length = 505 Score = 89.7 bits (221), Expect = 7e-18 Identities = 63/180 (35%), Positives = 95/180 (52%), Gaps = 5/180 (2%) Frame = -1 Query: 658 LSTHPEWQEKLREEV--LRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGS 485 L+ +PE Q++ R+E+ L GS + T + L+++ M + E LRLYAPV I R Sbjct: 330 LAKYPEHQQRCRDEIRELLGDGSSI-TWEHLSQMPYTTMCIKECLRLYAPVVNISRLLDK 388 Query: 484 DLEV-GGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFS 308 + G +P G + I I +H + W ED F P+RF + HP A + FS Sbjct: 389 PITFPDGRSLPAGITVFINIWALHHNPYFW-EDPQVFNPLRFSRENSEK-IHPYAFIPFS 446 Query: 307 SGPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVHAPMDV--ITLRPKFGLPMILKSI 134 +G R+CIGQ FA+IE K +A+ L R F L+P + P V + L+ K G+ + K + Sbjct: 447 AGLRNCIGQHFAIIECKVAVALTLLR--FKLAPDHSRPPQPVRQVVLKSKNGIHVFAKKV 504
>THAS_RAT (P49430) Thromboxane-A synthase (EC 5.3.99.5) (TXA synthase) (TXS)| Length = 533 Score = 89.7 bits (221), Expect = 7e-18 Identities = 54/153 (35%), Positives = 78/153 (50%), Gaps = 2/153 (1%) Frame = -1 Query: 658 LSTHPEWQEKLREEV--LRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGS 485 L+THPE QE+L +EV E ++ L ++M + ETLR+Y P R+A Sbjct: 357 LATHPECQERLLKEVDLFMEKHPAPEYCNLQEGLPYLDMVVAETLRMYPPAFRFTREAAQ 416 Query: 484 DLEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSS 305 D EV G +P G+VL I + +H D E W + F P RF AR + P L F + Sbjct: 417 DCEVLGQHIPAGSVLEIAVGALHHDPEHW-PNPETFDPERF-TAEARLQQKPFTYLPFGA 474 Query: 304 GPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPK 206 GPRSC+G ++ K + +L +F F P+ Sbjct: 475 GPRSCLGVRLGLLVVKLTLLQVLHKFRFEACPE 507
>CP4F2_HUMAN (P78329) Cytochrome P450 4F2 (EC 1.14.13.30) (CYPIVF2)| (Leukotriene-B(4) omega-hydroxylase) (Leukotriene-B(4) 20-monooxygenase) (Cytochrome P450-LTB-omega) Length = 520 Score = 89.4 bits (220), Expect = 9e-18 Identities = 55/148 (37%), Positives = 84/148 (56%), Gaps = 4/148 (2%) Frame = -1 Query: 658 LSTHPEWQEKLREEV---LRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAG 488 L+ HPE+QE+ R+EV L++ + D L L + M + E+LRL+ PV +I R Sbjct: 344 LAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVT 403 Query: 487 SDLEV-GGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSF 311 D+ + G +P+G + I + H + VW D + P RF+ + + P A + F Sbjct: 404 QDIVLPDGRVIPKGIICLISVFGTHHNPAVW-PDPEVYDPFRFDPENIKE-RSPLAFIPF 461 Query: 310 SSGPRSCIGQSFAMIEAKAVIAVILQRF 227 S+GPR+CIGQ+FAM E K V+A+ L RF Sbjct: 462 SAGPRNCIGQTFAMAEMKVVLALTLLRF 489
>THAS_HUMAN (P24557) Thromboxane-A synthase (EC 5.3.99.5) (TXA synthase) (TXS)| Length = 533 Score = 89.0 bits (219), Expect = 1e-17 Identities = 53/153 (34%), Positives = 76/153 (49%), Gaps = 2/153 (1%) Frame = -1 Query: 658 LSTHPEWQEKLREEV--LRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGS 485 L+T+P+ QEKL EV +E + L ++M + ETLR+Y P R+A Sbjct: 357 LATNPDCQEKLLREVDVFKEKHMAPEFCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQ 416 Query: 484 DLEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSS 305 D EV G ++P G VL + + +H D E W F P RF AR P L F + Sbjct: 417 DCEVLGQRIPAGAVLEMAVGALHHDPEHW-PSPETFNPERF-TAEARQQHRPFTYLPFGA 474 Query: 304 GPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPK 206 GPRSC+G ++E K + +L +F F P+ Sbjct: 475 GPRSCLGVRLGLLEVKLTLLHVLHKFRFQACPE 507
>CP4S3_DROME (Q9VXY0) Probable cytochrome P450 4s3 (EC 1.14.-.-) (CYPIVS3)| Length = 495 Score = 89.0 bits (219), Expect = 1e-17 Identities = 61/167 (36%), Positives = 86/167 (51%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSDL 479 LS +P+ Q++ EE G E + L + + ETLR+Y V RK DL Sbjct: 323 LSKNPDVQQRAFEEASELEGREKESMPYLEAV------IKETLRIYPSVPFFSRKVLEDL 376 Query: 478 EVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSGP 299 EVG + VP+G ++ I +HRD + + D F P RF V HP A +FS+GP Sbjct: 377 EVGKLTVPKGASISCLIYMLHRDPKNF-PDPERFDPDRFL--VNEKQMHPFAFAAFSAGP 433 Query: 298 RSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVHAPMDVITLRPKFG 158 R+CIGQ FAM+E K +A++L+ + F P H P + L K G Sbjct: 434 RNCIGQKFAMLELKTSLAMLLRSYRF--LPDKDHQPKPLAELVTKSG 478
>THAS_PIG (P47787) Thromboxane-A synthase (EC 5.3.99.5) (TXA synthase) (TXS)| Length = 534 Score = 89.0 bits (219), Expect = 1e-17 Identities = 59/174 (33%), Positives = 90/174 (51%), Gaps = 6/174 (3%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTGD---MLNKLHLVNMFLLETLRLYAPVSLIQRKAG 488 L+T+P+ QEKL EV + + P+ + + L ++M L ETLR+Y P R+A Sbjct: 358 LATNPDCQEKLLREV-DDFSKKHPSPEHCSLQQGLPYLDMVLSETLRMYPPAFRFTREAA 416 Query: 487 SDLEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFS 308 D EV G ++P GTVL + + +H D + W F P RF A+ + P L F Sbjct: 417 RDCEVLGQRIPAGTVLEVAVGALHHDPKHW-PHPETFDPERF-TAEAQRLQQPFTYLPFG 474 Query: 307 SGPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVHAPMDV---ITLRPKFGL 155 +GPRSC+G ++E K + IL++F F P+ P+ + L PK G+ Sbjct: 475 AGPRSCLGVQLGLLEIKLTLLHILRKFRFEACPE-TQVPLQLESKSALSPKNGV 527
>CP134_DROME (Q9VG40) Probable cytochrome P450 313a4 (EC 1.14.-.-)| (CYPCCCXIIIA4) Length = 478 Score = 89.0 bits (219), Expect = 1e-17 Identities = 54/154 (35%), Positives = 86/154 (55%), Gaps = 5/154 (3%) Frame = -1 Query: 658 LSTHPEWQEKLREEV---LRECGS-EVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKA 491 L+ PE+QE+ EE+ G +V D ++L ++ L E++R+ PV ++ R+ Sbjct: 299 LAMFPEYQERAFEEIKTIFPNTGDFDVSYADTQQMVYL-DLILNESMRVIPPVPVVSRQT 357 Query: 490 GSDLEVG-GIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLS 314 DL++ GI VP+G + I I +HR K++WG DA F P F + KHP A + Sbjct: 358 SQDLKLSNGIVVPKGVQIAIDIYHMHRSKKIWGPDAETFNPDHFLPHNIQ-DKHPYAYIP 416 Query: 313 FSSGPRSCIGQSFAMIEAKAVIAVILQRFSFSLS 212 F+ G R+CIG +A+I AK +A +L+ + F S Sbjct: 417 FTKGIRNCIGWRYALISAKVTLAKLLRNYRFKTS 450
>CP4FB_HUMAN (Q9HBI6) Cytochrome P450 4F11 (EC 1.14.14.1) (CYPIVF11)| Length = 524 Score = 87.8 bits (216), Expect = 3e-17 Identities = 57/148 (38%), Positives = 80/148 (54%), Gaps = 4/148 (2%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTG---DMLNKLHLVNMFLLETLRLYAPVSLIQRKAG 488 L+ HPE+QE+ R+EV P D L +L + M + E+LRL+ PV +I R Sbjct: 344 LAKHPEYQEQCRQEVQELLKDREPIEIEWDDLAQLPFLTMCIKESLRLHPPVPVISRCCT 403 Query: 487 SDLEV-GGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSF 311 D + G +P+G V I I IH + VW D + P RF + + P A + F Sbjct: 404 QDFVLPDGRVIPKGIVCLINIIGIHYNPTVW-PDPEVYDPFRFNQENIKE-RSPLAFIPF 461 Query: 310 SSGPRSCIGQSFAMIEAKAVIAVILQRF 227 S+GPR+CIGQ+FAM E K V+A+ L F Sbjct: 462 SAGPRNCIGQAFAMAEMKVVLALTLLHF 489
>C340_ORYLA (Q98T91) Cytochrome P450 3A40 (EC 1.14.14.1)| Length = 502 Score = 87.0 bits (214), Expect = 4e-17 Identities = 49/149 (32%), Positives = 86/149 (57%), Gaps = 1/149 (0%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTGDM-LNKLHLVNMFLLETLRLYAPVSLIQRKAGSD 482 L+T+PE +KL++E+ ++ P + L ++ ++ + E+LRLY + ++R A + Sbjct: 322 LATNPEVMKKLQKEIDATFPNKAPVQYVPLMEMEYLDCVVNESLRLYPIAARLERVAKAT 381 Query: 481 LEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSG 302 +EV G+ +P+ V+ +P +HRD E+W E +FKP RF + P + F +G Sbjct: 382 VEVNGLVIPKDMVVMVPTWPLHRDPELWPE-PEKFKPERFSK-ENKDTFDPYTYMPFGAG 439 Query: 301 PRSCIGQSFAMIEAKAVIAVILQRFSFSL 215 PR+CIG FA++ K + ILQ + FS+ Sbjct: 440 PRNCIGMRFALVMMKLAVVEILQTYDFSV 468
>CP4F3_HUMAN (Q08477) Cytochrome P450 4F3 (EC 1.14.13.30) (CYPIVF3)| (Leukotriene-B(4) omega-hydroxylase) (Leukotriene-B(4) 20-monooxygenase) (Cytochrome P450-LTB-omega) Length = 520 Score = 86.7 bits (213), Expect = 6e-17 Identities = 53/148 (35%), Positives = 83/148 (56%), Gaps = 4/148 (2%) Frame = -1 Query: 658 LSTHPEWQEKLREEV---LRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAG 488 L+ HPE+QE+ R+EV L++ + D L +L + M + E+LRL+ PV + R Sbjct: 344 LAKHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCT 403 Query: 487 SDLEV-GGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSF 311 D+ + G +P+G + I + H + VW D + P RF+ + + P A + F Sbjct: 404 QDIVLPDGRVIPKGIICLISVFGTHHNPAVW-PDPEVYDPFRFDPKNIKE-RSPLAFIPF 461 Query: 310 SSGPRSCIGQSFAMIEAKAVIAVILQRF 227 S+GPR+CIGQ+FAM E K V+ + L RF Sbjct: 462 SAGPRNCIGQAFAMAEMKVVLGLTLLRF 489
>CP4D8_DROME (Q9VS79) Cytochrome P450 4d8 (EC 1.14.-.-) (CYPIVD8)| Length = 463 Score = 86.3 bits (212), Expect = 7e-17 Identities = 59/179 (32%), Positives = 98/179 (54%), Gaps = 9/179 (5%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSE----VPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKA 491 LS HPE Q K+ EE+++ G++ V D L +L + + E+LR+Y PV ++ RK Sbjct: 283 LSRHPEVQAKMLEEIVQVLGTDRSRPVSIRD-LGELKYMECVIKESLRMYPPVPIVGRKL 341 Query: 490 GSDLEV-----GGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPN 326 +D + G +P G+ + I I +HR E + + +EF P R ENG A P Sbjct: 342 QTDFKYTHSVHGDGVIPAGSEIIIGIFGVHRQPETF-PNPDEFIPERHENGSRVA---PF 397 Query: 325 ALLSFSSGPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVHAPMDVITLRPKFGLPM 149 ++ FS+GPR+CIGQ FA +E K ++A I++ + + V ++++ LR + G + Sbjct: 398 KMIPFSAGPRNCIGQKFAQLEMKMMLAKIVREYELLPMGQRVECIVNIV-LRSETGFQL 455
>CP4P3_DROME (Q9V559) Probable cytochrome P450 4p3 (EC 1.14.-.-) (CYPIVP3)| Length = 515 Score = 86.3 bits (212), Expect = 7e-17 Identities = 55/160 (34%), Positives = 90/160 (56%), Gaps = 7/160 (4%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTGDM--LNKLHLVNMFLLETLRLYAPVSLIQRKAGS 485 +S +PE QEK +E+ E+ ++ LNKL + F+ ET+RL+ V + R+ Sbjct: 338 MSLYPEEQEKCYQEIQANIDDELNILNIGQLNKLKNLEYFIKETMRLFPSVPAMGRETTR 397 Query: 484 DLEVG-GIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRF--ENGVARAGKHPNALLS 314 + E+ G+ +P+G+ + + + IHR+ E W + EF+P RF EN R H A + Sbjct: 398 ETELSNGLILPKGSQIFVHVFDIHRNPEYW-DSPEEFRPERFLPENSQNR---HTYAYIP 453 Query: 313 FSSGPRSCIGQSFAMIEAKAVIAVILQRFSF--SLSPKYV 200 FS+G R+CIGQ FAM E K ++ +L++F + PK + Sbjct: 454 FSAGQRNCIGQKFAMQEMKTLMVALLKQFQILPEIDPKTI 493
>C13B1_CAEEL (O17624) Putative cytochrome P450 cyp-13B1 (EC 1.14.-.-)| Length = 527 Score = 86.3 bits (212), Expect = 7e-17 Identities = 48/146 (32%), Positives = 83/146 (56%), Gaps = 2/146 (1%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLI--QRKAGS 485 L+ HPE + +EEV GSE + D + KL ++ + E+LRLY PV+ R+ Sbjct: 336 LAKHPEKMKLAQEEVDTVVGSENVSYDDMTKLKYLDAVVRESLRLY-PVAWFACSRECVK 394 Query: 484 DLEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSS 305 +G I + +G + + ++HR KE+WGE+A++F P R+ + + +H + + F + Sbjct: 395 PTTLGDIYIDKGVKIEADVMSLHRSKEIWGENADDFVPERW---LEPSSRHTMSWIPFGA 451 Query: 304 GPRSCIGQSFAMIEAKAVIAVILQRF 227 GPR C+G + EAK +A +L+R+ Sbjct: 452 GPRQCVGMRLGLSEAKTALAHLLRRY 477
>C4D20_DROME (Q9W011) Probable cytochrome P450 4d20 (EC 1.14.-.-) (CYPIVD20)| Length = 510 Score = 84.3 bits (207), Expect = 3e-16 Identities = 50/145 (34%), Positives = 80/145 (55%), Gaps = 3/145 (2%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVP---TGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAG 488 ++ HPE Q+++ EE+ R G + T L L ++ + ET+RLY PV I R A Sbjct: 332 IARHPEVQQRIFEELQRVLGPDASAPVTQAQLQDLKYLDCVIKETMRLYPPVPAIGRHAQ 391 Query: 487 SDLEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFS 308 +LE+G +P T + + + HRD + D F+P RF G + A + FS Sbjct: 392 KELEIGDKTIPANTSIYLVLYYAHRDANYF-PDPLSFRPERFLED-QEQGHNTFAYVPFS 449 Query: 307 SGPRSCIGQSFAMIEAKAVIAVILQ 233 +GP++CIGQ FA++E K +I+ +L+ Sbjct: 450 AGPKNCIGQKFAVLEMKVLISKVLR 474
>CYPD_BACSU (O08394) Probable bifunctional P-450:NADPH-P450 reductase 1| [Includes: Cytochrome P450 102 (EC 1.14.14.1); NADPH--cytochrome P450 reductase (EC 1.6.2.4)] Length = 1061 Score = 84.3 bits (207), Expect = 3e-16 Identities = 53/165 (32%), Positives = 82/165 (49%), Gaps = 1/165 (0%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSDL 479 L HP+ +K EEV R PT + +L + M L E+LRL+ D Sbjct: 283 LLKHPDKLKKAYEEVDRVLTDAAPTYKQVLELTYIRMILNESLRLWPTAPAFSLYPKEDT 342 Query: 478 EVGG-IKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSG 302 +GG + +++ I +HRD++ WG+DA EF+P RFE+ + +A F +G Sbjct: 343 VIGGKFPITTNDRISVLIPQLHRDRDAWGKDAEEFRPERFEH---QDQVPHHAYKPFGNG 399 Query: 301 PRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVHAPMDVITLRP 167 R+CIG FA+ EA V+ +IL+ F+ Y +TL+P Sbjct: 400 QRACIGMQFALHEATLVLGMILKYFTLIDHENYELDIKQTLTLKP 444
>CP4P1_DROME (Q9V558) Cytochrome P450 4p1 (EC 1.14.-.-) (CYPIVP1)| Length = 513 Score = 84.0 bits (206), Expect = 4e-16 Identities = 52/149 (34%), Positives = 87/149 (58%), Gaps = 5/149 (3%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTGDM--LNKLHLVNMFLLETLRLYAPVSLIQRKAGS 485 +S +P+ QE +E+ ++ D+ LNKL + F+ ET RL+ V ++ R+A Sbjct: 336 MSLNPDKQELCYQEIQEHIDDDLSNLDVGQLNKLKYLEYFMKETTRLFPSVPIMGREAVQ 395 Query: 484 DLEVG-GIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRF--ENGVARAGKHPNALLS 314 + E+ G+ +P+G +TI + IHR+ + W + EF+P RF EN R H A + Sbjct: 396 ETELANGLILPKGAQITIHVFDIHRNAKYW-DSPEEFRPERFLPENVQDR---HTYAYVP 451 Query: 313 FSSGPRSCIGQSFAMIEAKAVIAVILQRF 227 FS+G R+CIG+ +AM E K ++ V+L++F Sbjct: 452 FSAGQRNCIGKKYAMQEMKTLMVVLLKQF 480
>CP4C1_BLADI (P29981) Cytochrome P450 4C1 (EC 1.14.14.1) (CYPIVC1)| Length = 511 Score = 84.0 bits (206), Expect = 4e-16 Identities = 57/176 (32%), Positives = 95/176 (53%), Gaps = 4/176 (2%) Frame = -1 Query: 658 LSTHPEWQEKLREEV--LRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGS 485 L +HPE Q+K+ EE+ + + T L + + + E+LRL+ V I R Sbjct: 330 LGSHPEIQDKVYEELDHIFQGSDRSTTMRDLADMKYLERVIKESLRLFPSVPFIGRVLKE 389 Query: 484 DLEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRF-ENGVARAGKHPNALLSFS 308 D ++G VP G ++ + I +HR+++ + + F P F VA+ +HP A + FS Sbjct: 390 DTKIGDYLVPAGCMMNLQIYHVHRNQDQY-PNPEAFNPDNFLPERVAK--RHPYAYVPFS 446 Query: 307 SGPRSCIGQSFAMIEAKAVIAVILQRFSF-SLSPKYVHAPMDVITLRPKFGLPMIL 143 +GPR+CIGQ FA +E K V++ IL+ F S+ + M+ + LRP+ G+ + L Sbjct: 447 AGPRNCIGQKFATLEEKTVLSSILRNFKVRSIEKREDLTLMNELILRPESGIKVEL 502
>C4AA1_DROME (Q9V7G5) Probable cytochrome P450 4aa1 (EC 1.14.-.-) (CYPIVAA1)| Length = 514 Score = 83.6 bits (205), Expect = 5e-16 Identities = 64/179 (35%), Positives = 96/179 (53%), Gaps = 6/179 (3%) Frame = -1 Query: 658 LSTHPEWQEK--LREEVLRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGS 485 L+ +PE Q++ L + E + PT L+++ + M + E LRLY V LI RK G Sbjct: 332 LTQNPECQDRCVLELATIFEDSNRAPTMTDLHEMRYMEMCIKEALRLYPSVPLIARKLGE 391 Query: 484 DLEVGGIKVPEGT-VLTIPIATIHRDKEVWGEDANEFKPMRF--ENGVARAGKHPNALLS 314 ++ + +P G+ V P AT HR ++ D +F+P RF EN R HP A L Sbjct: 392 EVRLAKHTLPAGSNVFICPYAT-HRLAHIY-PDPEKFQPERFSPENSENR---HPYAFLP 446 Query: 313 FSSGPRSCIGQSFAMIEAKAVIAVILQRFS-FSLSPKYVHAPMDVITLRPKFGLPMILK 140 FS+GPR CIG FA++E K +++ +L+ + ++ K A ITLR GL + LK Sbjct: 447 FSAGPRYCIGNRFAIMEIKTIVSRLLRSYQLLPVTGKTTIAATFRITLRASGGLWVRLK 505
>CP6L1_BLAGE (Q9GQM9) Cytochrome P450 6l1 (EC 1.14.-.-) (CYPVIL1)| Length = 503 Score = 83.2 bits (204), Expect = 6e-16 Identities = 48/146 (32%), Positives = 80/146 (54%), Gaps = 4/146 (2%) Frame = -1 Query: 658 LSTHPEWQEKLREEV--LRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGS 485 L+ HPE Q++LR E+ + C T + + K+ ++M + E LR Y P+S I R Sbjct: 314 LALHPEIQDRLRTEIQEVTACHGGQVTYEGVKKMSYLDMVVSEVLRKYPPMSFIDRVCLH 373 Query: 484 DLEVGG--IKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSF 311 D + G + + +GT + + + +HRD ++ D +F P RF N ++G HP + + F Sbjct: 374 DYHIPGTDVVIEKGTPIFVSLLGLHRDS-IFYPDPEDFNPERF-NKEKKSGVHPFSYIPF 431 Query: 310 SSGPRSCIGQSFAMIEAKAVIAVILQ 233 GPR+CIG ++ K VI ++LQ Sbjct: 432 GDGPRNCIGLRLGLMSVKLVIIMLLQ 457
>C4AD1_DROME (Q9V4T3) Probable cytochrome P450 4ad1 (EC 1.14.-.-) (CYPIVAD1)| Length = 516 Score = 83.2 bits (204), Expect = 6e-16 Identities = 54/148 (36%), Positives = 82/148 (55%), Gaps = 4/148 (2%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVP-TGDM--LNKLHLVNMFLLETLRLYAPVSLIQRKAG 488 LS H E Q+K EE R G D+ L+++H + + + ETLRLY V LI R Sbjct: 321 LSRHSEIQQKAAEEQRRIFGENFAGEADLARLDQMHYLELIIRETLRLYPSVPLIARTNR 380 Query: 487 SDLEVGGIKVPE-GTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSF 311 + +++ G KV + TV+ IA + +K + +D F+P RFEN G + F Sbjct: 381 NPIDINGTKVAKCTTVIMCLIAMGYNEK--YFDDPCTFRPERFENPTGNVGIEAFKSVPF 438 Query: 310 SSGPRSCIGQSFAMIEAKAVIAVILQRF 227 S+GPR CI + FAM + KA+++ +L+RF Sbjct: 439 SAGPRRCIAEKFAMYQMKALLSQLLRRF 466
>C4D21_DROME (Q9VLZ7) Probable cytochrome P450 4d21 (EC 1.14.-.-) (CYPIVD21)| Length = 511 Score = 82.8 bits (203), Expect = 8e-16 Identities = 48/147 (32%), Positives = 84/147 (57%), Gaps = 3/147 (2%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVP---TGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAG 488 +S HP+ QE + EE++ G + T L +L ++ + ET+RL+ PV ++ R Sbjct: 332 ISRHPKVQECIYEELVSVLGPDPDASVTQTKLLELKYLDCVIKETMRLHPPVPILGRYIP 391 Query: 487 SDLEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFS 308 DL++G I +P T + + ++RD E + D FKP R+ + + P A + FS Sbjct: 392 EDLKIGEITIPGNTSILLMPYYVYRDPEYF-PDPLVFKPERWMDMKTTSNTPPLAYIPFS 450 Query: 307 SGPRSCIGQSFAMIEAKAVIAVILQRF 227 SGP++CIGQ FA ++ KA+I+ +++ + Sbjct: 451 SGPKNCIGQKFANLQMKALISKVIRHY 477
>C6A13_DROME (Q9V4U9) Probable cytochrome P450 6a13 (EC 1.14.-.-) (CYPVIA13)| Length = 493 Score = 82.8 bits (203), Expect = 8e-16 Identities = 50/155 (32%), Positives = 88/155 (56%), Gaps = 4/155 (2%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLR--ECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGS 485 L+ +P+ QE+LR EVL + ++ T D + ++ ++ + ETLR Y + + R++ Sbjct: 311 LALNPDVQERLRVEVLAVLKRNNQKLTYDSVQEMPYLDQVVAETLRKYPILPHLLRRSTK 370 Query: 484 DLEV--GGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSF 311 + ++ + + G+ + IP+ +IH D E++ D +F P RFE +A +HP A L F Sbjct: 371 EYQIPNSNLILEPGSKIIIPVHSIHHDPELY-PDPEKFDPSRFEPEEIKA-RHPFAYLPF 428 Query: 310 SSGPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPK 206 GPR+CIG+ F ++ K + +L+ F FS S K Sbjct: 429 GEGPRNCIGERFGKLQVKVGLVYLLRDFKFSRSEK 463
>CP52F_CANTR (P30608) Cytochrome P450 52A6 (EC 1.14.14.-) (CYPLIIA6)| (Alkane-inducible P450-ALK3) Length = 524 Score = 82.4 bits (202), Expect = 1e-15 Identities = 61/172 (35%), Positives = 86/172 (50%), Gaps = 16/172 (9%) Frame = -1 Query: 658 LSTHPEWQEKLREEVL------RECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQR 497 L+ HPE KLREE+ E E T + L + + L ETLR+Y V + R Sbjct: 337 LARHPEIWSKLREEIEVNFGVGEESRVEEITFESLKRCEYLKAILNETLRMYPSVPVNSR 396 Query: 496 KAGSD--LEVGG-------IKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMR-FENGVA 347 A D L GG I +P+G+ + + HR +E +G+DA++F+P R FE Sbjct: 397 TATRDTTLPRGGGPNGTDPIFIPKGSTVAYIVYKTHRLEEYYGKDADDFRPERWFEPSTK 456 Query: 346 RAGKHPNALLSFSSGPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVHAP 191 + G A + F+ GPR C+GQ FA+ EA VI ++Q F SP V P Sbjct: 457 KLGW---AYVPFNGGPRICLGQQFALTEASYVITRLVQMFETVSSPPDVEYP 505
>C505_FUSOX (Q9Y8G7) Bifunctional P-450:NADPH-P450 reductase (Fatty acid| omega-hydroxylase) (P450foxy) [Includes: Cytochrome P450 505 (EC 1.14.14.1); NADPH--cytochrome P450 reductase (EC 1.6.2.4)] Length = 1066 Score = 82.0 bits (201), Expect = 1e-15 Identities = 55/168 (32%), Positives = 91/168 (54%), Gaps = 4/168 (2%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSDL 479 L +PE K+++EV G + L KL ++ L ETLRL +P++ +A D Sbjct: 282 LLKNPEAYSKVQKEVDEVVGRGPVLVEHLTKLPYISAVLRETLRLNSPITAFGLEAIDDT 341 Query: 478 EVGG-IKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRF-ENGVARAGK-HPNALLSFS 308 +GG V +G ++T ++ H D V+G DA++F P R ++ AR K +PN F Sbjct: 342 FLGGKYLVKKGEIVTALLSRGHVDPVVYGNDADKFIPERMLDDEFARLNKEYPNCWKPFG 401 Query: 307 SGPRSCIGQSFAMIEAKAVIAVILQRFSFSLS-PKYVHAPMDVITLRP 167 +G R+CIG+ FA E+ + V+ Q F+F+++ P Y +T++P Sbjct: 402 NGKRACIGRPFAWQESLLAMVVLFQNFNFTMTDPNYALEIKQTLTIKP 449
>CP56_YEAST (P21595) Cytochrome P450-DIT2 (EC 1.14.14.-) (Cytochrome P450 56)| Length = 489 Score = 81.6 bits (200), Expect = 2e-15 Identities = 57/174 (32%), Positives = 91/174 (52%), Gaps = 13/174 (7%) Frame = -1 Query: 643 EWQEKLREEVLRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVS-LIQRKAGSDLEVGG 467 EWQEKLR+EV G P G L L L+N FL E +R+Y P+S +I R ++G Sbjct: 315 EWQEKLRKEVN---GITDPKG--LADLPLLNAFLFEVVRMYPPLSTIINRCTTKTCKLGA 369 Query: 466 -IKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVA------RAGKHPNALLSFS 308 I +P+G + D + WG A++FKP R+ + + R K+ A+ F Sbjct: 370 EIVIPKGVYVGYNNFGTSHDPKTWGTTADDFKPERWGSDIETIRKNWRMAKNRCAVTGFH 429 Query: 307 SGPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVH-----APMDVITLRPKF 161 G R+C+G+ A+ E + +A +L++F +SL P++ P+ + L+ KF Sbjct: 430 GGRRACLGEKLALTEMRISLAEMLKQFRWSLDPEWEEKLTPAGPLCPLNLKLKF 483
>C81E1_GLYEC (P93147) Cytochrome P450 81E1 (EC 1.14.13.89) (Isoflavone| 2'-hydroxylase) (P450 91A4) (CYP GE-3) Length = 499 Score = 81.6 bits (200), Expect = 2e-15 Identities = 63/187 (33%), Positives = 95/187 (50%), Gaps = 5/187 (2%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSE--VPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGS 485 L HPE +K+++E+ G + V D+ +L N+ + ETLRLY P L+ + S Sbjct: 318 LLNHPEVLKKVKDELDTHVGQDRLVDESDLPKLTYLKNV-INETLRLYTPAPLLLPHSTS 376 Query: 484 D-LEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFS 308 D +GG KVP+ T++ I IHRD E+W E A FKP RFE + G+ L++F Sbjct: 377 DECNIGGYKVPQDTIVLINAWAIHRDPELWTE-ATTFKPERFE----KKGE-LEKLIAFG 430 Query: 307 SGPRSCIGQSFAMIEAKAVIAVILQRFSFSL--SPKYVHAPMDVITLRPKFGLPMILKSI 134 G R+C G+ A+ +A+++Q F + L K A D TL L + KS Sbjct: 431 MGRRACPGEGLAIRAISMTLALLIQCFDWKLINGDKIDLAERDGFTLTKLVPLKAMCKSR 490 Query: 133 EI*KNVY 113 + V+ Sbjct: 491 PVINKVF 497
>CP4E3_DROME (Q9VL92) Cytochrome P450 4e3 (EC 1.14.-.-) (CYPIVE3)| Length = 526 Score = 81.6 bits (200), Expect = 2e-15 Identities = 48/147 (32%), Positives = 78/147 (53%), Gaps = 3/147 (2%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTG---DMLNKLHLVNMFLLETLRLYAPVSLIQRKAG 488 LS HP+ Q KL E G ++ + K+ +++F+ E R+Y V I R Sbjct: 323 LSRHPDVQRKLYREQCEVMGHDMNRSVSFQEIAKMKYLDLFIKEAQRVYPSVPFIGRYCD 382 Query: 487 SDLEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFS 308 D ++ G VP+GT L + + + + ++ +D + F+P RFE P L FS Sbjct: 383 KDYDINGSIVPKGTTLNLALILLGYNDRIF-KDPHHFRPERFEEEKPA----PFEYLPFS 437 Query: 307 SGPRSCIGQSFAMIEAKAVIAVILQRF 227 +GPR+CIGQ FA++E K VI+ +++ F Sbjct: 438 AGPRNCIGQKFALLELKTVISKVVRSF 464
>CP136_MYCTU (P95099) Putative cytochrome P450 136 (EC 1.14.-.-)| Length = 492 Score = 81.3 bits (199), Expect = 2e-15 Identities = 52/178 (29%), Positives = 87/178 (48%), Gaps = 5/178 (2%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSDL 479 L+ HPEWQ++ R+E R + + L +L +++ + E++RL PV R+ D Sbjct: 319 LAAHPEWQQRCRDESDRHGDGPLDI-ESLEQLESLDLVMNESIRLVTPVQWAMRQTVRDT 377 Query: 478 EVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSGP 299 E+ G +P+GT + HR E+W D F P RF +H A F G Sbjct: 378 ELLGYYLPKGTNVIAYPGMNHRLPEIW-TDPLTFDPERFTEPRNEHKRHRYAFTPFGGGV 436 Query: 298 RSCIGQSFAMIEAKAVIAVILQRFSFSLS-----PKYVHAPMDVITLRPKFGLPMILK 140 CIG F +E K ++ +L+R+ LS P++ ++ M + P G+P++L+ Sbjct: 437 HKCIGMVFDQLEIKTILHRLLRRYRLELSRPDYQPRWDYSAMPI----PMDGMPIVLR 490
>CP4E5_DROMT (O44221) Cytochrome P450 4e5, mitochondrial precursor (EC 1.14.-.-)| (CYPIVE5) Length = 522 Score = 81.3 bits (199), Expect = 2e-15 Identities = 51/147 (34%), Positives = 79/147 (53%), Gaps = 3/147 (2%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEV---PTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAG 488 LS PE Q KL EE G+E+ T ++ + +++F+ E R+Y V I R Sbjct: 323 LSRFPEEQRKLYEEQQAVMGNELNRDATFQEISAMKYLDLFIKEAQRVYPSVPFIGRYTD 382 Query: 487 SDLEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFS 308 D + G +P+GT L + I + D V+ E+ + F P RFE + P + FS Sbjct: 383 KDYNIHGTIMPKGTTLNLGIIVLGYDDRVF-EEPHRFYPERFE----KQKPGPFEYVPFS 437 Query: 307 SGPRSCIGQSFAMIEAKAVIAVILQRF 227 +GPR+CIGQ FA++E K VI+ +++ F Sbjct: 438 AGPRNCIGQKFALLELKTVISKLVRTF 464
>CP313_DROME (Q9VHP4) Probable cytochrome P450 313b1 (EC 1.14.-.-)| (CYPCCCXIIIB1) Length = 502 Score = 81.3 bits (199), Expect = 2e-15 Identities = 50/155 (32%), Positives = 82/155 (52%), Gaps = 8/155 (5%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTGDM----LNKLHLVNMFLLETLRLYAPVSLIQRKA 491 L+ HP +QEKL +E++ E P+GD+ L +L M + E +RL+APV ++ R A Sbjct: 323 LAMHPCYQEKLHKELVTELP---PSGDINLEQLQRLEYTEMVINEAMRLFAPVPMVLRSA 379 Query: 490 GSDLEV----GGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNA 323 D+++ G +P GT + I I + RD+ VWG + + P G+ +H A Sbjct: 380 DQDIQLKRGDGEFLIPRGTQIGIDIYNMQRDERVWGPLSRTYNP-DAHFGLDSPQRHAFA 438 Query: 322 LLSFSSGPRSCIGQSFAMIEAKAVIAVILQRFSFS 218 + F+ G R CIG +A + K ++A I + + S Sbjct: 439 FVPFTKGLRMCIGYRYAQMLMKLLLARIFRSYRIS 473
>C6A14_DROME (Q9V4U7) Probable cytochrome P450 6a14 (EC 1.14.-.-) (CYPVIA14)| Length = 509 Score = 80.9 bits (198), Expect = 3e-15 Identities = 52/154 (33%), Positives = 83/154 (53%), Gaps = 5/154 (3%) Frame = -1 Query: 658 LSTHPEWQEKLREE---VLRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAG 488 L+ P+ Q++LREE VL D+L ++ ++ L ETLR + + + R+ Sbjct: 329 LALQPDIQQRLREEIESVLANVDGGELNYDVLAQMTYLDQVLSETLRKHPLLPHLIRETT 388 Query: 487 SDLEV--GGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLS 314 D ++ I + +G + IP+ IH D E++ E +F P RF+ + +HP A L Sbjct: 389 KDYQIPNSDIVLDKGILALIPVHNIHHDPEIYPEP-EKFDPSRFDPEEVK-NRHPMAYLP 446 Query: 313 FSSGPRSCIGQSFAMIEAKAVIAVILQRFSFSLS 212 F GPR+CIG F I+AK + +L+RF FS+S Sbjct: 447 FGDGPRNCIGLRFGKIQAKIGLVSLLRRFKFSVS 480
>CP4P2_DROME (Q9V557) Probable cytochrome P450 4p2 (EC 1.14.-.-) (CYPIVP2)| Length = 520 Score = 80.1 bits (196), Expect = 5e-15 Identities = 52/142 (36%), Positives = 84/142 (59%), Gaps = 5/142 (3%) Frame = -1 Query: 574 LNKLHLVNMFLLETLRLYAPVSLIQRKAGSDLEV-GGIKVPEGTVLTIPIATIHRDKEVW 398 L+KL+ + F+ ET+RLY + ++ R+ + E+ G+ +P+ + + I + IHR+ + W Sbjct: 371 LSKLNYLGYFIKETMRLYPSIPIMGRQTLQETELENGLILPKRSQINIHVFDIHRNPKYW 430 Query: 397 GEDANEFKPMRF--ENGVARAGKHPNALLSFSSGPRSCIGQSFAMIEAKAVIAVILQRFS 224 E EF+P RF +N + R HP A + FS+G R+CIGQ +AM E K ++ VIL+ F Sbjct: 431 -ESPEEFRPERFLPQNCLKR---HPYAYIPFSAGQRNCIGQKYAMQEMKTLMVVILKHFK 486 Query: 223 F--SLSPKYVHAPMDVITLRPK 164 + PK + + ITLR K Sbjct: 487 ILPVIDPKSIVFQVG-ITLRFK 507
>C28D2_DROME (Q9VMT6) Probable cytochrome P450 28d2 (EC 1.14.-.-) (CYPXXVIIID2)| Length = 501 Score = 80.1 bits (196), Expect = 5e-15 Identities = 50/159 (31%), Positives = 82/159 (51%), Gaps = 8/159 (5%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSDL 479 L +PE Q+K+R+E+ GS T D +++L ++ + ETLRL++P ++ Sbjct: 321 LGRNPEEQDKVRKEI----GSADLTFDQMSELPHLDACIYETLRLFSPQVAARKLVTEPF 376 Query: 478 EVGG-----IKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRF---ENGVARAGKHPNA 323 E + + G V+TIP+ +H D + + ED FKP RF G ++ + Sbjct: 377 EFANKNGRTVHLKPGDVVTIPVKALHHDPQYY-EDPLTFKPERFLESNGGGMKSYRDRGV 435 Query: 322 LLSFSSGPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPK 206 L+F GPR C G FA+ + KA + IL+ F ++PK Sbjct: 436 YLAFGDGPRHCPGMRFALTQLKAALVEILRNFEIKVNPK 474
>CP135_DROME (Q9VGB5) Probable cytochrome P450 313a5 (EC 1.14.-.-)| (CYPCCCXIIIA5) Length = 487 Score = 79.7 bits (195), Expect = 7e-15 Identities = 53/158 (33%), Positives = 82/158 (51%), Gaps = 6/158 (3%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLR--ECGSEVPTGDM-LNKLHLVNMFLLETLRLYAPVSLIQRKAG 488 ++ P++Q+ + EE+ G E L KL ++ L ET+RL V L+ R+ Sbjct: 308 MAMFPKYQDNVFEELAEVFPSGGEFEASHADLEKLVKLDRVLHETMRLIPAVPLLIRQTS 367 Query: 487 SDLEVG-GIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRF--ENGVARAGKHPNALL 317 +++ G +PEG L I I HR+K++WG AN F P F EN AR P + L Sbjct: 368 HSIQLSNGFYIPEGVTLMIDIFHTHRNKDIWGPQANAFNPDNFLPENKRARP---PYSYL 424 Query: 316 SFSSGPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKY 203 FS G ++C+G ++I AK +A IL+ + S + Y Sbjct: 425 PFSKGKKTCLGWKLSLISAKLALAKILRNYMLSTTFLY 462
>CP391_DROME (Q9VQD2) Probable cytochrome P450 309a1 (EC 1.14.-.-) (CYPCCCIXA1)| Length = 529 Score = 78.6 bits (192), Expect = 2e-14 Identities = 48/150 (32%), Positives = 68/150 (45%), Gaps = 6/150 (4%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTG-DMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSD 482 LS H E QEKLR E+L SE D +N L ++ E+LRL P+ R Sbjct: 348 LSEHHEEQEKLRSEILEALASEGQISYDQINNLPYLDQCFNESLRLTTPIGFFMRICTKP 407 Query: 481 LEVG-----GIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALL 317 ++ + + G + +P H D +++ E A+EF+P RFENG A L Sbjct: 408 TQINLGDDKTLDLEPGVTVMVPAYQYHHDNDIYPE-ASEFRPDRFENGAASVLTKRGCFL 466 Query: 316 SFSSGPRSCIGQSFAMIEAKAVIAVILQRF 227 F GPR C+G + K I IL + Sbjct: 467 PFGDGPRICLGMRVGQLSVKTAIVHILSNY 496
>CP4E1_DROME (Q9V4T5) Probable cytochrome P450 4e1 (EC 1.14.-.-) (CYPIVE1)| Length = 531 Score = 78.6 bits (192), Expect = 2e-14 Identities = 50/148 (33%), Positives = 80/148 (54%), Gaps = 4/148 (2%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEV----PTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKA 491 LS HP+ QEKL E G+ T ++ + +++F+ E RLY V I R Sbjct: 323 LSRHPDEQEKLFNEQCDVMGASGLGRDATFQEISTMKHLDLFIKEAQRLYPSVPFIGRFT 382 Query: 490 GSDLEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSF 311 D + G VP+GT L + + + + V+ +D ++F+P RF+ R P + F Sbjct: 383 EKDYVIDGDIVPKGTTLNLGLLMLGYNDRVF-KDPHKFQPERFD----REKPGPFEYVPF 437 Query: 310 SSGPRSCIGQSFAMIEAKAVIAVILQRF 227 S+GPR+CIGQ FA++E K V++ I++ F Sbjct: 438 SAGPRNCIGQKFALLEIKTVVSKIIRNF 465
>CP52J_CANMA (Q12588) Cytochrome P450 52A10 (EC 1.14.14.-) (CYPLIIA10)| (Alkane-inducible P450-ALK7) Length = 519 Score = 78.6 bits (192), Expect = 2e-14 Identities = 61/173 (35%), Positives = 89/173 (51%), Gaps = 17/173 (9%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGS------EVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQR 497 L +PE KLR+E+ + G E + ++L + L ETLRLY V R Sbjct: 331 LGRNPEVWSKLRQEIGHKFGLDSYSRVEDISFELLKLCEYLKAVLNETLRLYPSVPRNAR 390 Query: 496 KAGSD--LEVGG-------IKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMR-FENGVA 347 A + L GG I V +G + + + RD++ +G+DANEF+P R FE V Sbjct: 391 FAAKNTTLPHGGGPDGMSPILVRKGQTVMYSVYALQRDEKYYGKDANEFRPERWFEPEVR 450 Query: 346 RAGKHPNALLSFSSGPRSCIGQSFAMIEAKAVIAVILQRF-SFSLSPKYVHAP 191 + G A L F+ GPR C+GQ FA+ EA V+A ++Q F + LSP+ + P Sbjct: 451 KLGW---AFLPFNGGPRICLGQQFALTEASYVLARLIQSFETLELSPEAAYPP 500
>C97B3_ARATH (O23365) Cytochrome P450 97B3 (EC 1.14.-.-)| Length = 580 Score = 78.2 bits (191), Expect = 2e-14 Identities = 53/177 (29%), Positives = 84/177 (47%), Gaps = 29/177 (16%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKA---- 491 LS +PE K + E+ G PT + + KL + + ++E LRL+ L+ R+ Sbjct: 375 LSQNPEKIRKAQAEIDAVLGQGPPTYESMKKLEYIRLIVVEVLRLFPQPPLLIRRTLKPE 434 Query: 490 ----GSDLEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRF-----ENGV---- 350 G E G KVP+GT + I + +HR W ++ ++F+P RF NG+ Sbjct: 435 TLPGGHKGEKEGHKVPKGTDIFISVYNLHRSPYFW-DNPHDFEPERFLRTKESNGIEGWA 493 Query: 349 ------ARAGKHPN------ALLSFSSGPRSCIGQSFAMIEAKAVIAVILQRFSFSL 215 + +PN A L F GPR CIG FA++E+ +A++ Q+F L Sbjct: 494 GFDPSRSPGALYPNEIIADFAFLPFGGGPRKCIGDQFALMESTVALAMLFQKFDVEL 550
>CP52C_CANMA (P16496) Cytochrome P450 52A3 (EC 1.14.14.-) (CYPLIIA3)| (Alkane-inducible P450-ALK1-A) (P450-CM1) (CYP52A3-A) (Cytochrome P-450ALK) Length = 522 Score = 77.8 bits (190), Expect = 3e-14 Identities = 65/178 (36%), Positives = 86/178 (48%), Gaps = 16/178 (8%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRE--CGSEVPTGDM----LNKLHLVNMFLLETLRLYAPVSLIQR 497 L+ +P+ KLREEV G E ++ L K + L ETLR+Y V + R Sbjct: 335 LARNPKIWNKLREEVEVNFGLGDEARVDEISFETLKKCEYLKAVLNETLRMYPSVPINFR 394 Query: 496 KAGSD--LEVGGIK-------VPEGTVLTIPIATIHRDKEVWGEDANEFKPMR-FENGVA 347 A D L GG K VP+G+ + + HR K+ +GEDA EF+P R FE Sbjct: 395 TATRDTTLPRGGGKDGNSPIFVPKGSSVVYSVYKTHRLKQFYGEDAYEFRPERWFEPSTR 454 Query: 346 RAGKHPNALLSFSSGPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVHAPMDVITL 173 + G A L F+ GPR C+GQ FA+ EA VIA + Q F S + P I L Sbjct: 455 KLGW---AYLPFNGGPRICLGQQFALTEASYVIARLAQMFEHLESKDETYPPNKCIHL 509
>C71AM_ARATH (Q9STL1) Cytochrome P450 71A22 (EC 1.14.-.-)| Length = 490 Score = 77.4 bits (189), Expect = 3e-14 Identities = 46/157 (29%), Positives = 80/157 (50%), Gaps = 2/157 (1%) Frame = -1 Query: 646 PEWQEKLREEVLREC-GSEVPTGDMLNKLHLVNMFLLETLRLYAPVSL-IQRKAGSDLEV 473 PE +L+EEV C G+ + D + ++ + + ET+RL+ P+ L + ++ D+ + Sbjct: 312 PECLNRLQEEVRTICKGNSSVSEDDIKDMNYLKAVIKETMRLHPPLPLMVPHESTQDVRL 371 Query: 472 GGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSGPRS 293 G +P GT + I I R+ WG DA +F+P R N H L+ F +G R Sbjct: 372 GDYHIPAGTQVMINAWAIGREAATWGPDAEKFRPERHLNSSVDFRGHNFELIPFGAGRRI 431 Query: 292 CIGQSFAMIEAKAVIAVILQRFSFSLSPKYVHAPMDV 182 C SFA+I + +A ++ R+ + L +Y+ +V Sbjct: 432 CPAISFAVILIEVTLANLVHRYDWRLPEEYIEDQTNV 468
>CP191_CARAU (P79690) Cytochrome P450 19 type 1 (EC 1.14.14.1) (Brain aromatase)| (CYPXIXA1) (Estrogen synthetase) (P-450AROM) Length = 510 Score = 77.4 bits (189), Expect = 3e-14 Identities = 45/139 (32%), Positives = 77/139 (55%), Gaps = 4/139 (2%) Frame = -1 Query: 628 LREEVLRECGSEVPTGDM----LNKLHLVNMFLLETLRLYAPVSLIQRKAGSDLEVGGIK 461 + E++++E S++ D+ L KL+++ F+ E+LR + V I R+A D E+ G + Sbjct: 326 VEEQIVQEIQSQIGERDVESADLQKLNVLERFIKESLRFHPVVDFIMRRALEDDEIDGYR 385 Query: 460 VPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSGPRSCIGQ 281 V +GT L + I +H+ + + + NEF FEN V P F GPR+C+G+ Sbjct: 386 VAKGTNLILNIGRMHKSE--FFQKPNEFNLENFENTVPSRYFQP-----FGCGPRACVGK 438 Query: 280 SFAMIEAKAVIAVILQRFS 224 AM+ KA++ +L RF+ Sbjct: 439 HIAMVMTKAILVTLLSRFT 457
>CP139_MYCTU (P63719) Putative cytochrome P450 139 (EC 1.14.-.-)| Length = 430 Score = 77.4 bits (189), Expect = 3e-14 Identities = 56/176 (31%), Positives = 81/176 (46%), Gaps = 3/176 (1%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSDL 479 L T P E EV R G VP D L+ L +N + ETLRLY+P + R+ DL Sbjct: 250 LLTVPGTWESAASEVARVLGGRVPAADDLSALTYLNGVVHETLRLYSPGVISARRVLRDL 309 Query: 478 EVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGK-HPNALLSFSSG 302 G ++ G +L HR E+W E EF+P+R++ A K P+ + FS G Sbjct: 310 WFDGHRIRAGRLLIFSAYVTHRLPEIWPE-PTEFRPLRWDPNAADYRKPAPHEFIPFSGG 368 Query: 301 PRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVH--APMDVITLRPKFGLPMILK 140 CIG A E ++A ++ R L + H + LRP GL + ++ Sbjct: 369 LHRCIGAVMATTEMTVILARLVARAMLQLPAQRTHRIRAANFAALRPWPGLTVEIR 424
>CP139_MYCBO (P63720) Putative cytochrome P450 139 (EC 1.14.-.-)| Length = 430 Score = 77.4 bits (189), Expect = 3e-14 Identities = 56/176 (31%), Positives = 81/176 (46%), Gaps = 3/176 (1%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSDL 479 L T P E EV R G VP D L+ L +N + ETLRLY+P + R+ DL Sbjct: 250 LLTVPGTWESAASEVARVLGGRVPAADDLSALTYLNGVVHETLRLYSPGVISARRVLRDL 309 Query: 478 EVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGK-HPNALLSFSSG 302 G ++ G +L HR E+W E EF+P+R++ A K P+ + FS G Sbjct: 310 WFDGHRIRAGRLLIFSAYVTHRLPEIWPE-PTEFRPLRWDPNAADYRKPAPHEFIPFSGG 368 Query: 301 PRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVH--APMDVITLRPKFGLPMILK 140 CIG A E ++A ++ R L + H + LRP GL + ++ Sbjct: 369 LHRCIGAVMATTEMTVILARLVARAMLQLPAQRTHRIRAANFAALRPWPGLTVEIR 424
>CP4E2_DROME (Q27606) Cytochrome P450 4e2 (EC 1.14.-.-) (CYPIVE2)| Length = 526 Score = 77.4 bits (189), Expect = 3e-14 Identities = 48/148 (32%), Positives = 84/148 (56%), Gaps = 4/148 (2%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEV----PTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKA 491 LS H + Q KL +E G+ T ++++ +++F+ E R+Y V I R Sbjct: 323 LSRHQDEQRKLFKEQREVMGNSELGRDATFQEISQMKYLDLFIKEAQRVYPSVPFIGRFT 382 Query: 490 GSDLEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSF 311 D + G VP+GT L + + + +++V+ +D ++F+P RFE + + G P + F Sbjct: 383 EKDYVIDGDLVPKGTTLNLGLVMLGYNEKVF-KDPHKFRPERFE--LEKPG--PFEYVPF 437 Query: 310 SSGPRSCIGQSFAMIEAKAVIAVILQRF 227 S+GPR+CIGQ FA++E K V++ I++ F Sbjct: 438 SAGPRNCIGQKFALLEIKTVVSKIIRNF 465
>C71A8_MENPI (Q42716) Cytochrome P450 71A8 (EC 1.14.-.-)| Length = 502 Score = 76.6 bits (187), Expect = 6e-14 Identities = 49/150 (32%), Positives = 78/150 (52%), Gaps = 2/150 (1%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVP-TGDMLNKLHLVNMFLLETLRLYAPVSL-IQRKAGS 485 L HPE +KL+ EV + + T D + K+H + + ET+R + P+ L + R A + Sbjct: 324 LLRHPEIMKKLQSEVRQVVKDKHNITDDDIEKMHYLKAVMKETMRFHTPIPLLVPRVARN 383 Query: 484 DLEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSS 305 D+EV G VP GT++ I I RD W ++ +F+P RF N L+ F + Sbjct: 384 DVEVMGYDVPVGTMVMINAWAIGRDPTSW-DEPEKFRPERFLNSSVDFKGLDFELIPFGA 442 Query: 304 GPRSCIGQSFAMIEAKAVIAVILQRFSFSL 215 G R C G +F M + +A ++Q+F + L Sbjct: 443 GRRGCPGTTFPMATLEFTLANLMQKFDWEL 472
>C4G15_DROME (Q9VYY4) Cytochrome P450 4g15 (EC 1.14.-.-) (CYPIVG15)| Length = 574 Score = 76.6 bits (187), Expect = 6e-14 Identities = 40/112 (35%), Positives = 67/112 (59%), Gaps = 6/112 (5%) Frame = -1 Query: 544 LLETLRLYAPVSLIQRKAGSDLEV--GGIKVPEGTVLTIPIATIHRDKEVWGE----DAN 383 L+ETLR+Y PV LI R+ DL++ G +P G +T+ +HR+ +V+ D + Sbjct: 435 LMETLRMYPPVPLIARELQEDLKLNSGNYVIPRGATVTVATVLLHRNPKVYANPNVFDPD 494 Query: 382 EFKPMRFENGVARAGKHPNALLSFSSGPRSCIGQSFAMIEAKAVIAVILQRF 227 F P R +A +H A + FS+GPRSC+G+ +AM++ K +++ IL+ + Sbjct: 495 NFLPER------QANRHYYAFVPFSAGPRSCVGRKYAMLKLKILLSTILRNY 540
>C28D1_DROME (Q9VMT5) Probable cytochrome P450 28d1 (EC 1.14.-.-) (CYPXXVIIID1)| Length = 502 Score = 76.3 bits (186), Expect = 8e-14 Identities = 47/158 (29%), Positives = 81/158 (51%), Gaps = 7/158 (4%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSDL 479 L+ +P+ Q KLREE+ G+ T + +++L + ETLR+++PV ++ Sbjct: 322 LARNPKEQMKLREEI----GTAELTFEQISELPFTEACIHETLRIFSPVLAARKVVTEPC 377 Query: 478 EVGG-----IKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFEN--GVARAGKHPNAL 320 E+ +K+ G V+ IP+ +H D + + E+ FKP RF N G A+ + Sbjct: 378 ELTNKNGVSVKLRPGDVVIIPVNALHHDPQYY-EEPQSFKPERFLNINGGAKKYRDQGLF 436 Query: 319 LSFSSGPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPK 206 F GPR C G F++ + KA + I++ F ++PK Sbjct: 437 FGFGDGPRICPGMRFSLTQIKAALVEIVRNFDIKVNPK 474
>CP52V_CANAP (P43083) Cytochrome P450 52E1 (EC 1.14.14.-) (CYPLIIE1)| Length = 519 Score = 75.5 bits (184), Expect = 1e-13 Identities = 56/157 (35%), Positives = 78/157 (49%), Gaps = 12/157 (7%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGS---EVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAG 488 L +PE +LRE VL E GS E PT + L + ++ + E LRL+ V L R+A Sbjct: 328 LGAYPEVYAELREAVLSEFGSTDVETPTFEQLKQCKVLQNVIREVLRLHPNVPLNFRQAI 387 Query: 487 SD--LEVGG-------IKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGK 335 D L GG + VP+G + ++ R ++WG DA F+P R+ N A Sbjct: 388 VDTKLPTGGGPNGDQPVFVPKGQNVFYSTYSMQRRTDIWGPDATTFRPDRW-NEPREALA 446 Query: 334 HPNALLSFSSGPRSCIGQSFAMIEAKAVIAVILQRFS 224 + F+ GPR C+GQ FA+ EA I I Q FS Sbjct: 447 SGWDYIPFNGGPRICLGQQFALTEASYTIVRICQEFS 483
>CP52K_CANMA (Q12589) Cytochrome P450 52A11 (EC 1.14.14.-) (CYPLIIA11)| (Alkane-inducible P450-ALK8) Length = 519 Score = 75.5 bits (184), Expect = 1e-13 Identities = 59/173 (34%), Positives = 88/173 (50%), Gaps = 17/173 (9%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTG------DMLNKLHLVNMFLLETLRLYAPVSLIQR 497 L +PE KLREE+ + G + + ++L + + ETLRLY V R Sbjct: 331 LGRNPEVWSKLREEIGDKFGLDPDSRIEDISFELLKLCEYLKAVINETLRLYPSVPRNGR 390 Query: 496 KAGSD--LEVGG-------IKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMR-FENGVA 347 A ++ L GG I V +G + + + RD++ +G+DANEF+P R FE V Sbjct: 391 FAAANTTLPHGGGPDGMSPILVRKGQTVMYSVYALQRDEKYYGKDANEFRPERWFEPEVR 450 Query: 346 RAGKHPNALLSFSSGPRSCIGQSFAMIEAKAVIAVILQRF-SFSLSPKYVHAP 191 + G A L F+ GPR C+GQ FA+ EA V+ ++Q F + LSP + P Sbjct: 451 KLGW---AFLPFNGGPRICLGQQFALTEASYVLVRLIQSFETLELSPDAPYPP 500
>CP21A_PIG (P15540) Cytochrome P450 21 (EC 1.14.99.10) (Cytochrome P450 XXI)| (Steroid 21-hydroxylase) (21-OHase) (P450-C21) (P-450c21) Length = 492 Score = 75.5 bits (184), Expect = 1e-13 Identities = 55/148 (37%), Positives = 79/148 (53%), Gaps = 6/148 (4%) Frame = -1 Query: 649 HPEWQEKLREEVLRE-----CGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSL-IQRKAG 488 HPE Q +L+EE+ RE GS VP D +L L+N + E LRL V L + +A Sbjct: 309 HPEIQWRLQEELDRELGPGAAGSRVPYKDRA-RLPLLNATIAEVLRLRPVVPLALPHRAT 367 Query: 487 SDLEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFS 308 + G +PEGTV+ + H D+ VW E +EF+P RF G +P+A L+F Sbjct: 368 RPSSIFGYDIPEGTVVIPNLQGAHLDETVW-EQPHEFRPDRF----LAPGANPSA-LAFG 421 Query: 307 SGPRSCIGQSFAMIEAKAVIAVILQRFS 224 G R C+G+ A +E V+ +LQ F+ Sbjct: 422 CGARVCLGEPLARLELFVVLVQLLQAFT 449
>CP52M_DEBHA (Q9Y758) Cytochrome P450 52A13 (EC 1.14.14.-) (Alkane hydroxylase| 2) (Alkane-inducible p450alk 2) (DH-ALK2) Length = 519 Score = 75.1 bits (183), Expect = 2e-13 Identities = 55/160 (34%), Positives = 81/160 (50%), Gaps = 16/160 (10%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECG-------SEVPTGDMLNKLHLVNMFLLETLRLY--APVSL 506 L+ HP KL+EE+ G SE+ T + L K + + E LRLY PV+ Sbjct: 333 LARHPRVFNKLKEEIYEAFGKGDDARVSEI-TFESLKKCEYLKWVMNEMLRLYPSVPVNF 391 Query: 505 IQRKAGSDLEVGG-------IKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVA 347 + L GG I V +GT + + + HR +E +G+DA+EFKP R+ A Sbjct: 392 RVATKRTTLPRGGGPDGNSPIYVGKGTTVAYSVYSTHRMEEYYGKDADEFKPERW----A 447 Query: 346 RAGKHPNALLSFSSGPRSCIGQSFAMIEAKAVIAVILQRF 227 + K A + F+ GPR C+GQ FA+ EA ++ +LQ F Sbjct: 448 ESRKLGWAYVPFNGGPRICLGQQFALTEASYIVTRLLQMF 487
>CP312_DROME (Q9VVN6) Probable cytochrome P450 312a1 (EC 1.14.-.-) (CYPCCCXIIA1)| Length = 510 Score = 75.1 bits (183), Expect = 2e-13 Identities = 55/167 (32%), Positives = 88/167 (52%), Gaps = 5/167 (2%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECG---SEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAG 488 ++ HPE Q++ REEV CG SE + + + +L + + ETLR+Y L RKA Sbjct: 332 MTLHPEHQQRCREEVWSVCGKDKSEPISIEQVRQLEFLEACIKETLRMYPSGPLTARKAT 391 Query: 487 SDLEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFS 308 ++ + +P+G+ + I + R K+ + D FKP R+ G A + F Sbjct: 392 ANCTINDFFIPKGSDVIISPIYMGRCKDFF-PDPMVFKPDRWAIG-AEPKIEATTFIPFM 449 Query: 307 SGPRSCIGQSFAMIEAKAVIAVILQRFSFS-LSPKYVHAPMD-VITL 173 +G RSC+GQ +AM+ K V+A +L+ F F L + V ++ VITL Sbjct: 450 AGARSCMGQRYAMVMLKMVLAHLLRNFLFEPLGERQVKLKLNFVITL 496
>C28C1_DROME (Q9VYT8) Probable cytochrome P450 28c1 (EC 1.14.-.-) (CYPXXVIIIC1)| Length = 505 Score = 75.1 bits (183), Expect = 2e-13 Identities = 48/158 (30%), Positives = 79/158 (50%), Gaps = 7/158 (4%) Frame = -1 Query: 658 LSTHPEWQEKLREEV-LRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSD 482 L +P+ Q +L EE+ L G +P D L L ++ E+LR+Y + + Sbjct: 316 LGRNPDCQRRLYEELQLVNPGGYLPDLDALIDLPYLSACFNESLRIYPAGGWASKTCTKE 375 Query: 481 LEVGG------IKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNAL 320 E+ G +K+ G + +PI +H D +++ E + F+P RF +G + K Sbjct: 376 YELRGSHHSEPLKLRPGDHVMVPIYALHNDPDLYPEP-DVFRPERFLDGGLKNCKQQGIF 434 Query: 319 LSFSSGPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPK 206 L F +GPR C+G + AKA +A I+QRF +SP+ Sbjct: 435 LGFGNGPRQCVGMRLGLAMAKAALAAIVQRFEVVVSPR 472
>CP46A_MOUSE (Q9WVK8) Cytochrome p450 46A1 (EC 1.14.13.98) (Cholesterol| 24-hydroxylase) (CH24H) Length = 500 Score = 74.7 bits (182), Expect = 2e-13 Identities = 58/165 (35%), Positives = 78/165 (47%), Gaps = 1/165 (0%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTG-DMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSD 482 LS PE +L+ EV GS+ + L +L ++ L E+LRLY P R + Sbjct: 318 LSRQPEIVARLQAEVDEVVGSKRHLDYEDLGRLQYLSQVLKESLRLYPPAWGTFRLLEEE 377 Query: 481 LEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSG 302 + G++VP T L + R + + ED F P RF G A K FS G Sbjct: 378 TLIDGVRVPGNTPLLFSTYVMGR-MDTYFEDPLTFNPDRFGPG---APKPRFTYFPFSLG 433 Query: 301 PRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVHAPMDVITLRP 167 RSCIGQ FA +E K V+A +LQR F L P + TL+P Sbjct: 434 HRSCIGQQFAQMEVKVVMAKLLQRIEFRLVPGQRFGLQEQATLKP 478
>C97B2_SOYBN (O48921) Cytochrome P450 97B2 (EC 1.14.-.-)| Length = 576 Score = 74.7 bits (182), Expect = 2e-13 Identities = 54/177 (30%), Positives = 83/177 (46%), Gaps = 29/177 (16%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTGDMLNKLHLVNMFLLETLRLYA-PVSLIQRKAGSD 482 L+ +P +K + EV G+ PT + L +L + + ++E LRLY P LI+R SD Sbjct: 369 LAQNPSKMKKAQAEVDLVLGTGRPTFESLKELQYIRLIVVEALRLYPQPPLLIRRSLKSD 428 Query: 481 LEVGGIK-------VPEGTVLTIPIATIHRDKEVWGEDANEFKPMRF------ENGVARA 341 + GG K +P GT + I + +HR W + ++F+P RF E A Sbjct: 429 VLPGGHKGEKDGYAIPAGTDVFISVYNLHRSPYFW-DRPDDFEPERFLVQNKNEEIEGWA 487 Query: 340 GKHPN---------------ALLSFSSGPRSCIGQSFAMIEAKAVIAVILQRFSFSL 215 G P+ A L F GPR C+G FA++E+ + ++LQ F L Sbjct: 488 GLDPSRSPGALYPNEVISDFAFLPFGGGPRKCVGDQFALMESTVALTMLLQNFDVEL 544
>CP46A_HUMAN (Q9Y6A2) Cytochrome p450 46A1 (EC 1.14.13.98) (Cholesterol| 24-hydroxylase) (CH24H) Length = 500 Score = 74.3 bits (181), Expect = 3e-13 Identities = 58/165 (35%), Positives = 78/165 (47%), Gaps = 1/165 (0%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTG-DMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSD 482 LS PE +L+ EV GS+ + L +L ++ L E+LRLY P R + Sbjct: 318 LSRQPEIVARLQAEVDEVIGSKRYLDFEDLGRLQYLSQVLKESLRLYPPAWGTFRLLEEE 377 Query: 481 LEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSG 302 + G++VP T L + R + + ED F P RF G A K FS G Sbjct: 378 TLIDGVRVPGNTPLLFSTYVMGR-MDTYFEDPLTFNPDRFGPG---APKPRFTYFPFSLG 433 Query: 301 PRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVHAPMDVITLRP 167 RSCIGQ FA +E K V+A +LQR F L P + TL+P Sbjct: 434 HRSCIGQQFAQMEVKVVMAKLLQRLEFRLVPGQRFGLQEQATLKP 478
>CP310_DROME (Q9VJ71) Probable cytochrome P450 310a1 (EC 1.14.-.-) (CYPCCCXA1)| Length = 492 Score = 73.9 bits (180), Expect = 4e-13 Identities = 60/191 (31%), Positives = 88/191 (46%), Gaps = 17/191 (8%) Frame = -1 Query: 634 EKLREEVLRECGSEVPTGDM----LNKLHLVNMFLLETLRLYAPVSLIQRKAGSDLEVGG 467 EKLR E+ +E +E G + LN L ++M L ETLR Y P+ +I+R + Sbjct: 307 EKLRAEI-KELSNE--NGQLKFEELNGLRYMDMCLKETLRKYPPLPIIERVCRKSYSLPN 363 Query: 466 IK--VPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGK-----HPNALLSFS 308 K + EG L +P+ +HRD++ + E ++KP+RF G+ N + F Sbjct: 364 SKFTIDEGKTLMVPLLAMHRDEKYFSEPM-KYKPLRFLQTANDVGQCEDKTKSNVFIGFG 422 Query: 307 SGPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYV------HAPMDVITLRPKFGLPMI 146 G C+GQ+FA + K + +LQ F L V H P I K GL + Sbjct: 423 IGGSQCVGQNFAKLVIKVALIKLLQNFHLELDANQVKTLKVSHRPAPFI--HTKDGLKVK 480 Query: 145 LKSIEI*KNVY 113 LK EI Y Sbjct: 481 LKRREINTKFY 491
>C4AC3_DROME (Q9VMS7) Probable cytochrome P450 4ac3 (EC 1.14.-.-) (CYPIVAC3)| Length = 509 Score = 73.9 bits (180), Expect = 4e-13 Identities = 49/148 (33%), Positives = 82/148 (55%), Gaps = 4/148 (2%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTGDML--NKLHLVNMFLLETLRLYAPVSLIQRKAGS 485 L+ H + QE+ EE L++ ++ M N+L + + E+LRL+ +I R Sbjct: 333 LALHADVQERCYEE-LQDLPEDIDEVSMFQFNELIHLECVIKESLRLFPSAPIIGRTCIE 391 Query: 484 DLEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRF--ENGVARAGKHPNALLSF 311 + + G+ +P+ ++I I I RD + + N+F P RF EN V R HP A + F Sbjct: 392 ESVMNGLVLPKNAQISIHIYDIMRDARHFPKP-NQFLPERFLPENSVNR---HPFAFVPF 447 Query: 310 SSGPRSCIGQSFAMIEAKAVIAVILQRF 227 S+GPR+CIGQ F ++E K ++A +++ F Sbjct: 448 SAGPRNCIGQKFGVLEIKVLLAAVIRNF 475
>C71BM_ARATH (Q9LTM1) Cytochrome P450 71B22 (EC 1.14.-.-)| Length = 500 Score = 73.6 bits (179), Expect = 5e-13 Identities = 50/152 (32%), Positives = 81/152 (53%), Gaps = 4/152 (2%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGS--EVPTGDMLNKLHLVNMFLLETLRLYAPVSLI-QRKAG 488 L+ HP +KL++E+ G E T L K+H + + + ET RL+ P L+ R+ Sbjct: 317 LARHPRVMKKLQQEIREILGDNKEKITEQDLEKVHYLKLVIEETFRLHPPAPLLLPRETM 376 Query: 487 SDLEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRF-ENGVARAGKHPNALLSF 311 SDL++ G +P+ T++ I +I RD W E+ N+F P RF ++ V G+H LL F Sbjct: 377 SDLKIQGYNIPKNTMIEINTYSIGRDPNCW-ENPNDFNPERFIDSPVEYKGQH-YELLPF 434 Query: 310 SSGPRSCIGQSFAMIEAKAVIAVILQRFSFSL 215 +G R C G + + + + +L F +SL Sbjct: 435 GAGRRICPGMATGITIVELGLLNVLYFFDWSL 466
>CP6A8_DROME (Q27593) Cytochrome P450 6a8 (EC 1.14.-.-) (CYPVIA8)| Length = 506 Score = 73.6 bits (179), Expect = 5e-13 Identities = 53/156 (33%), Positives = 80/156 (51%), Gaps = 5/156 (3%) Frame = -1 Query: 658 LSTHPEWQEKLREEV--LRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGS 485 L+ +P+ Q+K+R EV + E + T + L +N L ETLRLY V + R A Sbjct: 326 LAKNPDIQDKVRAEVEEVIEQHDQNFTYECTKDLKYLNQVLDETLRLYTIVPNLDRMAAK 385 Query: 484 DLEVGG---IKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLS 314 V G + G + IP + IH D ++ E EF+P RF + AG+ A L Sbjct: 386 RYVVPGHPNFVIEAGQSVIIPSSAIHHDPSIYPEPF-EFRPERFSPEES-AGRPSVAWLP 443 Query: 313 FSSGPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPK 206 F GPR+CIG F ++A+ +A++++ F FS K Sbjct: 444 FGDGPRNCIGLRFGQMQARIGLALLIRNFKFSTCSK 479
>CP133_DROME (Q9VGB3) Probable cytochrome P450 313a3 (EC 1.14.-.-)| (CYPCCCXIIIA3) Length = 492 Score = 73.6 bits (179), Expect = 5e-13 Identities = 49/157 (31%), Positives = 79/157 (50%), Gaps = 5/157 (3%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRE----CGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKA 491 L+ PE Q+ + +E L+E G T D L ++ + + ETLRL V R+ Sbjct: 313 LAMFPEHQDTVYQE-LKELFPVAGDFEVTYDDLQRMVFLERVVNETLRLIPSVPFTPRET 371 Query: 490 GSDLEVG-GIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLS 314 D + G+ +P+G + I I HR+++ WG D + F P F R +HP A + Sbjct: 372 IRDFRLSSGVVIPKGVGIGIDIFATHRNRDHWGTDPSSFNPDHFLPDNVR-DRHPYAYIP 430 Query: 313 FSSGPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKY 203 FS G R+CIG + ++ +K ++ IL+ S S +Y Sbjct: 431 FSKGRRNCIGWKYGLMSSKLALSKILRNCKVSTSFRY 467
>C4AC1_DROME (Q9VMS9) Probable cytochrome P450 4ac1 (EC 1.14.-.-) (CYPIVAC1)| Length = 509 Score = 73.6 bits (179), Expect = 5e-13 Identities = 52/148 (35%), Positives = 83/148 (56%), Gaps = 4/148 (2%) Frame = -1 Query: 658 LSTHPEWQEKLREEV--LRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGS 485 L+ H + Q+K EEV L E ++ NKL + + E+LR++ V I R+ Sbjct: 333 LALHEDVQKKCYEEVENLPEDSDDISMFQF-NKLVYLECVIKESLRMFPSVPFIGRQCVE 391 Query: 484 DLEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRF--ENGVARAGKHPNALLSF 311 + V G+ +P+ T ++I I I RD + + + F+P RF EN V R HP A + F Sbjct: 392 ETVVNGMVMPKDTQISIHIYDIMRDPRHFPKP-DLFQPDRFLPENTVNR---HPFAYVPF 447 Query: 310 SSGPRSCIGQSFAMIEAKAVIAVILQRF 227 S+G R+CIGQ FA++E K ++A +++ F Sbjct: 448 SAGQRNCIGQKFAILEMKVLLAAVIRNF 475
>C4D14_DROME (O46051) Probable cytochrome P450 4d14 (EC 1.14.-.-) (CYPIVD14)| Length = 507 Score = 73.6 bits (179), Expect = 5e-13 Identities = 58/177 (32%), Positives = 91/177 (51%), Gaps = 4/177 (2%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVP---TGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAG 488 L+ HPE Q ++ +EV G + T +L +L + + E+LRL+ V +I R Sbjct: 331 LARHPEVQARVFQEVRDVIGDDKSAPVTMKLLGELKYLECVIKESLRLFPSVPIIGRYIS 390 Query: 487 SDLEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGK-HPNALLSF 311 D + G +P + + I I RD + + D +F P RF + R G+ P A F Sbjct: 391 QDTVLDGKLIPADSNVIILIYHAQRDPDYF-PDPEKFIPDRFS--MERKGEISPFAYTPF 447 Query: 310 SSGPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVHAPMDVITLRPKFGLPMILK 140 S+GPR+CIGQ FAM+E K+ I+ +++ F + V ++VI LR G+ LK Sbjct: 448 SAGPRNCIGQKFAMLEMKSTISKMVRHFELLPLGEEVQPVLNVI-LRSTTGINCGLK 503
>CP1A1_RAT (P00185) Cytochrome P450 1A1 (EC 1.14.14.1) (CYP1A1) (CYPIA1)| (P450-C) (P450MT2) [Contains: Cytochrome P450MT2A; Cytochrome P450MT2B] Length = 524 Score = 73.2 bits (178), Expect = 7e-13 Identities = 50/173 (28%), Positives = 85/173 (49%), Gaps = 3/173 (1%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSE-VPTGDMLNKLHLVNMFLLETLRLYAPVSL-IQRKAGS 485 L T+P Q K++EE+ G + P +L + F+LET R + V I Sbjct: 337 LVTNPRIQRKIQEELDTVIGRDRQPRLSDRPQLPYLEAFILETFRHSSFVPFTIPHSTIR 396 Query: 484 DLEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKH-PNALLSFS 308 D + G +P+G + + ++ D+E+WG D NEF+P RF KH ++ F Sbjct: 397 DTSLNGFYIPKGHCVFVNQWQVNHDQELWG-DPNEFRPERFLTSSGTLDKHLSEKVILFG 455 Query: 307 SGPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVHAPMDVITLRPKFGLPM 149 G R CIG++ +E +A++LQ+ F++SP + + + P +GL + Sbjct: 456 LGKRKCIGETIGRLEVFLFLAILLQQMEFNVSPG------EKVDMTPAYGLTL 502
>CP17A_PANTR (Q8HYN1) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 73.2 bits (178), Expect = 7e-13 Identities = 52/149 (34%), Positives = 81/149 (54%), Gaps = 4/149 (2%) Frame = -1 Query: 649 HPEWQEKLREEVLRECG-SEVPTGDMLNKLHLVNMFLLETLRLYAPVS--LIQRKAGSDL 479 +P+ ++KL EE+ + G S PT N+L L+ + E LRL PV+ LI KA D Sbjct: 321 NPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREVLRL-RPVAPMLIPHKANVDS 379 Query: 478 EVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPN-ALLSFSSG 302 +G V +GT + I + +H +++ W + ++F P RF N P+ + L F +G Sbjct: 380 SIGEFAVDKGTQVIINLWALHHNEKEWHQP-DQFMPERFLNPAGTQLISPSVSYLPFGAG 438 Query: 301 PRSCIGQSFAMIEAKAVIAVILQRFSFSL 215 PRSCIG+ A E ++A +LQRF + Sbjct: 439 PRSCIGEILARQELFLIMAWLLQRFDLEV 467
>CP17A_HUMAN (P05093) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-monooxygenase) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 73.2 bits (178), Expect = 7e-13 Identities = 52/149 (34%), Positives = 81/149 (54%), Gaps = 4/149 (2%) Frame = -1 Query: 649 HPEWQEKLREEVLRECG-SEVPTGDMLNKLHLVNMFLLETLRLYAPVS--LIQRKAGSDL 479 +P+ ++KL EE+ + G S PT N+L L+ + E LRL PV+ LI KA D Sbjct: 321 NPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREVLRL-RPVAPMLIPHKANVDS 379 Query: 478 EVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPN-ALLSFSSG 302 +G V +GT + I + +H +++ W + ++F P RF N P+ + L F +G Sbjct: 380 SIGEFAVDKGTEVIINLWALHHNEKEWHQP-DQFMPERFLNPAGTQLISPSVSYLPFGAG 438 Query: 301 PRSCIGQSFAMIEAKAVIAVILQRFSFSL 215 PRSCIG+ A E ++A +LQRF + Sbjct: 439 PRSCIGEILARQELFLIMAWLLQRFDLEV 467
>CP52L_DEBHA (Q9Y757) Cytochrome P450 52A12 (EC 1.14.14.-) (Alkane hydroxylase| 1) (Alkane-inducible p450alk 1) (DH-ALK2) Length = 519 Score = 73.2 bits (178), Expect = 7e-13 Identities = 55/160 (34%), Positives = 80/160 (50%), Gaps = 16/160 (10%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGS------EVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQR 497 L+ +P+ KL+EE+ + G E T + L K + L E LRLY V R Sbjct: 332 LARNPQVWLKLKEEIYEKFGKGDDARLEDITFESLKKCEYLKALLNEVLRLYPSVPQNFR 391 Query: 496 KAGSDLEV---GG------IKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMR-FENGVA 347 A D + GG I + +G +T + +HRD++ +G+D+ F+P R FE Sbjct: 392 VAQKDTSLPRGGGPNRDQPIFIAKGQTVTYTVYAMHRDEQFYGKDSEVFRPERWFEPETR 451 Query: 346 RAGKHPNALLSFSSGPRSCIGQSFAMIEAKAVIAVILQRF 227 + G A L F+ GPR C+GQ FA+ EA VIA + Q F Sbjct: 452 KLGW---AFLPFNGGPRICLGQQFALTEASYVIARLAQLF 488
>CP52A_CANTR (P10615) Cytochrome P450 52A1 (EC 1.14.14.-) (CYPLIIA1)| (Alkane-inducible P450-ALK1) Length = 543 Score = 73.2 bits (178), Expect = 7e-13 Identities = 55/160 (34%), Positives = 78/160 (48%), Gaps = 16/160 (10%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGS------EVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQR 497 LS +PE KLREE+ + G E + + L + + ETLR+Y V R Sbjct: 352 LSRNPEIFAKLREEIENKFGLGQDARVEEISFETLKSCEYLKAVINETLRIYPSVPHNFR 411 Query: 496 KA---------GSDLEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMR-FENGVA 347 A G + + I + +G V+ I HRDK+++GEDA F+P R FE Sbjct: 412 VATRNTTLPRGGGEGGLSPIAIKKGQVVMYTILATHRDKDIYGEDAYVFRPERWFEPETR 471 Query: 346 RAGKHPNALLSFSSGPRSCIGQSFAMIEAKAVIAVILQRF 227 + G A + F+ GPR C+GQ FA+ EA V +LQ F Sbjct: 472 KLGW---AYVPFNGGPRICLGQQFALTEASYVTVRLLQEF 508
>CP120_SYNY3 (Q59990) Putative cytochrome P450 120 (EC 1.14.-.-)| Length = 444 Score = 72.8 bits (177), Expect = 9e-13 Identities = 50/175 (28%), Positives = 86/175 (49%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSDL 479 L H + +E++R+E + S+ T + L K+ ++ L E LRL PV R+ D Sbjct: 270 LGQHSDIRERVRQEQNKLQLSQELTAETLKKMPYLDQVLQEVLRLIPPVGGGFRELIQDC 329 Query: 478 EVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSGP 299 + G P+G +++ I+ H D +++ D +F P RF + P A + F G Sbjct: 330 QFQGFHFPKGWLVSYQISQTHADPDLY-PDPEKFDPERFTPDGSATHNPPFAHVPFGGGL 388 Query: 298 RSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVHAPMDVITLRPKFGLPMILKSI 134 R C+G+ FA +E K ++Q+F ++L P + + RPK L + L S+ Sbjct: 389 RECLGKEFARLEMKLFATRLIQQFDWTLLPGQNLELVVTPSPRPKDNLRVKLHSL 443
>CP52E_CANMA (P24458) Cytochrome P450 52A5 (EC 1.14.14.-) (CYPLIIA5)| (Alkane-inducible P450-ALK2-A) (CYP52A3-B) Length = 523 Score = 72.8 bits (177), Expect = 9e-13 Identities = 60/178 (33%), Positives = 85/178 (47%), Gaps = 16/178 (8%) Frame = -1 Query: 658 LSTHPEWQEKLREEVL------RECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQR 497 L+ +P+ KLREE+ E + + + L K + L ETLR+Y V + R Sbjct: 336 LARNPKIWNKLREEIEVNFGLGEEARVDEISFETLKKCEYLKAVLNETLRMYPSVPVNFR 395 Query: 496 KAGSD--LEVGGIK-------VPEGTVLTIPIATIHRDKEVWGEDANEFKPMR-FENGVA 347 A D L GG K VP+G+ + + HR +E +G+DA EF+P R FE Sbjct: 396 TATRDTTLPRGGGKDGTSPIFVPKGSSVVYTVYKTHRLEEYYGKDAYEFRPERWFEPSTR 455 Query: 346 RAGKHPNALLSFSSGPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVHAPMDVITL 173 + G A + F+ GPR C+GQ FA+ EA VI + Q F S + P I L Sbjct: 456 KLGW---AYVPFNGGPRICLGQQFALTEASYVITRLAQMFEHLESKDETYPPNKCIHL 510
>CP6D4_DROME (Q9VCW1) Probable cytochrome P450 6d4 (EC 1.14.-.-) (CYPVID4)| Length = 515 Score = 72.8 bits (177), Expect = 9e-13 Identities = 53/174 (30%), Positives = 85/174 (48%), Gaps = 6/174 (3%) Frame = -1 Query: 658 LSTHPEWQEKLREEV---LRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAG 488 L+ +PE ++L++EV L + ++ T D LNK+ +++ + ET+R Y + ++ R+ Sbjct: 334 LAQYPELLKRLQDEVDETLAKNDGKI-TYDSLNKMEFLDLCVQETIRKYPGLPILNRECT 392 Query: 487 SDLEVGGIK--VPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLS 314 D V +P+GT + I + IH D E + D + P RF +P A + Sbjct: 393 QDYTVPDTNHVIPKGTPVVISLYGIHHDAEYF-PDPETYDPERFSE--ESRNYNPTAFMP 449 Query: 313 FSSGPRSCIGQSFAMIEAKAVIAVILQRFSFS-LSPKYVHAPMDVITLRPKFGL 155 F GPR CI Q I +K I ILQ F+ +S + I L PK G+ Sbjct: 450 FGEGPRICIAQRMGRINSKLAIIKILQNFNVEVMSRSEIEFENSGIALIPKHGV 503
>CP4G1_DROME (Q9V3S0) Cytochrome P450 4g1 (EC 1.14.-.-) (CYPIVG1)| Length = 556 Score = 72.8 bits (177), Expect = 9e-13 Identities = 44/138 (31%), Positives = 77/138 (55%), Gaps = 6/138 (4%) Frame = -1 Query: 622 EEVLRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSDLEV--GGIKVPEG 449 + +LR+C D + +L + +LETLRLY PV LI R+ DL++ G VP+G Sbjct: 392 DNMLRDC----TFADTMEMKYLERV-ILETLRLYPPVPLIARRLDYDLKLASGPYTVPKG 446 Query: 448 TVLTIPIATIHRDKEVWGE----DANEFKPMRFENGVARAGKHPNALLSFSSGPRSCIGQ 281 T + + +HR +++ D + F P R N +H + + FS+GPRSC+G+ Sbjct: 447 TTVIVLQYCVHRRPDIYPNPTKFDPDNFLPERMAN------RHYYSFIPFSAGPRSCVGR 500 Query: 280 SFAMIEAKAVIAVILQRF 227 +AM++ K +++ I++ + Sbjct: 501 KYAMLKLKVLLSTIVRNY 518
>CP132_DROME (Q9VGB4) Probable cytochrome P450 313a2 (EC 1.14.-.-)| (CYPCCCXIIIA2) Length = 493 Score = 72.8 bits (177), Expect = 9e-13 Identities = 49/157 (31%), Positives = 76/157 (48%), Gaps = 5/157 (3%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLREC----GSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKA 491 L+ PE QE + E+ G EV D L +L ++ L ETLRL V R+ Sbjct: 313 LAMFPEHQEMVFNEIKEHFPLAKGIEVTHTD-LQQLVYLDRVLNETLRLMPSVPFSSRET 371 Query: 490 GSDLEVG-GIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLS 314 DL + G+ +P+G ++I I R+ + WG +A +F P F +HP A + Sbjct: 372 LEDLRLSNGVVIPKGMTISIDIFNTQRNTDYWGSEAAQFNPENFLPEKIH-DRHPYAFIP 430 Query: 313 FSSGPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKY 203 FS G R+CIG + ++ +K + IL+ + S Y Sbjct: 431 FSKGKRNCIGWRYGLMSSKLALVKILRNYKLKTSFPY 467
>C71AI_ARATH (Q9SAB6) Cytochrome P450 71A18 (EC 1.14.-.-)| Length = 497 Score = 72.4 bits (176), Expect = 1e-12 Identities = 49/154 (31%), Positives = 77/154 (50%), Gaps = 4/154 (2%) Frame = -1 Query: 658 LSTHPEWQEKLREEV---LRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLI-QRKA 491 L +PE +KL+ E+ +R GS + ++ N +L + E R++ P+ LI R Sbjct: 314 LIRNPECMKKLQNEIRSTIRPHGSYIKEKEVENMRYL-KAVIKEVFRVHPPLPLILPRLL 372 Query: 490 GSDLEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSF 311 D++V G + GT + I +IHRD +WG DA EFKP R + + F Sbjct: 373 TEDVKVKGYDIAAGTEVLINAWSIHRDPAIWGPDAEEFKPERHLDSTLDYHGQDLKYIPF 432 Query: 310 SSGPRSCIGQSFAMIEAKAVIAVILQRFSFSLSP 209 SG R C G + AM + +A ++ RF +S+ P Sbjct: 433 GSGRRICPGINLAMGLVEVTLANLVGRFDWSVDP 466
>C86A2_ARATH (O23066) Cytochrome P450 86A2 (EC 1.14.-.-)| Length = 553 Score = 72.4 bits (176), Expect = 1e-12 Identities = 55/184 (29%), Positives = 90/184 (48%), Gaps = 16/184 (8%) Frame = -1 Query: 658 LSTHPEWQEKLREEV----LRECGSEVPTG-------DMLNKLHLVNMFLLETLRLYAPV 512 ++THP ++K+ E+ + G++V + D +++L + L ETLRLY V Sbjct: 323 ITTHPTVEDKIVREICSVLIETRGTDVSSWTAEPLEFDEVDRLVYLKAALSETLRLYPSV 382 Query: 511 SLIQRKA-GSDLEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGK 335 + D+ G VP G+ +T I R K WGED EFKP R+ + GK Sbjct: 383 PEDSKHVVNDDILPDGTFVPAGSSVTYSIYAAGRMKSTWGEDCLEFKPERWIS--PDDGK 440 Query: 334 HPN----ALLSFSSGPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVHAPMDVITLRP 167 N ++F++GPR C+G+ A ++ K + A +L R +++P + +TL Sbjct: 441 FVNHDQYRFVAFNAGPRICLGKDLAYLQMKTIAAAVLLRHRLTVAPGHKVEQKMSLTLFM 500 Query: 166 KFGL 155 K GL Sbjct: 501 KNGL 504
>CP53_ASPNG (P17549) Benzoate 4-monooxygenase (EC 1.14.13.12)| (Benzoate-para-hydroxylase) (Cytochrome P450 53) (BpH) Length = 517 Score = 72.4 bits (176), Expect = 1e-12 Identities = 46/158 (29%), Positives = 85/158 (53%), Gaps = 6/158 (3%) Frame = -1 Query: 595 EVPTGDMLNKLHLVNMFLLETLRLYAPVSL-IQRK--AGSD-LEVGGIKVPEGTVLTIPI 428 +VPT M+ + + + ET+R+++ ++ + R+ AG+ + + G G V+++P Sbjct: 357 DVPTHAMVKDIPYLQWVIWETMRIHSTSAMGLPREIPAGNPPVTISGHTFYPGDVVSVPS 416 Query: 427 ATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSGPRSCIGQSFAMIEAKAVI 248 TIHR KE+WG DA +F P R++ + A + FS+GPR+C+G++ A +E + Sbjct: 417 YTIHRSKEIWGPDAEQFVPERWD-PARLTPRQKAAFIPFSTGPRACVGRNVAEMELLVIC 475 Query: 247 AVILQRFSFSLSPKYVHAPMDVIT--LRPKFGLPMILK 140 + + F F + + PM+ LR GL + +K Sbjct: 476 GTVFRLFEFEMQQE---GPMETREGFLRKPLGLQVGMK 510
>KO1_ARATH (Q93ZB2) Ent-kaurene oxidase (EC 1.14.13.78) (AtKO1) (Cytochrome| P450 701A3) Length = 509 Score = 72.0 bits (175), Expect = 1e-12 Identities = 46/149 (30%), Positives = 75/149 (50%), Gaps = 1/149 (0%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQ-RKAGSD 482 L+ HP Q++L +E+ CG E + L+++ +N ETLR Y+P L+ R A D Sbjct: 332 LAKHPSVQDRLCKEIQNVCGGEKFKEEQLSQVPYLNGVFHETLRKYSPAPLVPIRYAHED 391 Query: 481 LEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSG 302 ++GG VP G+ + I I + DK+ W E ++ P RF + + ++F +G Sbjct: 392 TQIGGYHVPAGSEIAINIYGCNMDKKRW-ERPEDWWPERFLDDGKYETSDLHKTMAFGAG 450 Query: 301 PRSCIGQSFAMIEAKAVIAVILQRFSFSL 215 R C G A + A I ++Q F + L Sbjct: 451 KRVCAGALQASLMAGIAIGRLVQEFEWKL 479
>C4AE1_DROME (O46054) Cytochrome P450 4ae1 (EC 1.14.-.-) (CYPIVAE1)| Length = 496 Score = 72.0 bits (175), Expect = 1e-12 Identities = 53/176 (30%), Positives = 90/176 (51%), Gaps = 3/176 (1%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTGDMLNK---LHLVNMFLLETLRLYAPVSLIQRKAG 488 LS H Q+KL EE+ G ++ G +L+ L ++ + E+LRLY P+ + R Sbjct: 320 LSRHEAVQQKLFEELRMHYGQDLFRGVILSDFATLPYLSCVVKESLRLYPPIPAVARCLE 379 Query: 487 SDLEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFS 308 DL + +P GT + + + + RD+ ++ D F+P R G P + + FS Sbjct: 380 KDLVIDEGYIPVGTNVVVLLWQLLRDEAIF-TDPLVFQPER-HLGEEAPRLSPYSYIPFS 437 Query: 307 SGPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVHAPMDVITLRPKFGLPMILK 140 +GPR+CIGQ FA++E K ++ +++ + V P I LR K G+ + L+ Sbjct: 438 AGPRNCIGQKFALLEMKTMVTKVIRHYQLLPMGADVE-PSIKIVLRSKSGVNVGLR 492
>CP9H1_DROME (Q9V6H1) Probable cytochrome P450 9h1 (EC 1.14.-.-) (CYPIXH1)| Length = 518 Score = 72.0 bits (175), Expect = 1e-12 Identities = 50/153 (32%), Positives = 80/153 (52%), Gaps = 9/153 (5%) Frame = -1 Query: 658 LSTHPEWQEKLREEVL---RECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAG 488 L +P Q++L EE++ E + T D L K+ ++M +LE LR + P R+ Sbjct: 335 LCLNPTVQDRLYEEIISVHEELKGQPLTYDKLTKMKYLDMVVLEALRKWPPSISTDRECR 394 Query: 487 SDLEV---GGIKV---PEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPN 326 D+++ G K+ +G VL IPI ++H D E + ED F P RF +G A + Sbjct: 395 QDIDLFDENGQKLFSARKGDVLQIPIFSLHHDPENF-EDPEFFNPERFADGHALESR--- 450 Query: 325 ALLSFSSGPRSCIGQSFAMIEAKAVIAVILQRF 227 + F GPR+CIG A++E K+++ +L F Sbjct: 451 VYMPFGVGPRNCIGNRMALMELKSIVYQLLLNF 483
>CP17A_PAPCY (Q8HYN0) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 72.0 bits (175), Expect = 1e-12 Identities = 51/149 (34%), Positives = 81/149 (54%), Gaps = 4/149 (2%) Frame = -1 Query: 649 HPEWQEKLREEVLRECG-SEVPTGDMLNKLHLVNMFLLETLRLYAPVS--LIQRKAGSDL 479 +P+ ++KL EE+ + G S PT N+L L+ + E LR+ PV+ LI KA D Sbjct: 321 NPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREVLRI-RPVAPMLIPHKANVDS 379 Query: 478 EVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPN-ALLSFSSG 302 +G V +GT + I + +H +++ W + ++F P RF N P+ + L F +G Sbjct: 380 SIGEFAVDKGTHVIINLWALHHNEKEWHQP-DQFMPERFLNPAGTQLISPSLSYLPFGAG 438 Query: 301 PRSCIGQSFAMIEAKAVIAVILQRFSFSL 215 PRSCIG+ A E ++A +LQRF + Sbjct: 439 PRSCIGEILARQELFLIMAWLLQRFDLEV 467
>CP17A_MACMU (Q8HYM9) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 72.0 bits (175), Expect = 1e-12 Identities = 51/149 (34%), Positives = 81/149 (54%), Gaps = 4/149 (2%) Frame = -1 Query: 649 HPEWQEKLREEVLRECG-SEVPTGDMLNKLHLVNMFLLETLRLYAPVS--LIQRKAGSDL 479 +P+ ++KL EE+ + G S PT N+L L+ + E LR+ PV+ LI KA D Sbjct: 321 NPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREVLRI-RPVAPMLIPHKANVDS 379 Query: 478 EVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPN-ALLSFSSG 302 +G V +GT + I + +H +++ W + ++F P RF N P+ + L F +G Sbjct: 380 SIGEFAVDKGTHVIINLWALHHNEKEWHQP-DQFMPERFLNPAGTQLISPSLSYLPFGAG 438 Query: 301 PRSCIGQSFAMIEAKAVIAVILQRFSFSL 215 PRSCIG+ A E ++A +LQRF + Sbjct: 439 PRSCIGEILARQELFLIMAWLLQRFDLEV 467
>CP17A_MACFA (Q2XVA1) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 72.0 bits (175), Expect = 1e-12 Identities = 51/149 (34%), Positives = 81/149 (54%), Gaps = 4/149 (2%) Frame = -1 Query: 649 HPEWQEKLREEVLRECG-SEVPTGDMLNKLHLVNMFLLETLRLYAPVS--LIQRKAGSDL 479 +P+ ++KL EE+ + G S PT N+L L+ + E LR+ PV+ LI KA D Sbjct: 321 NPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREVLRI-RPVAPMLIPHKANVDS 379 Query: 478 EVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPN-ALLSFSSG 302 +G V +GT + I + +H +++ W + ++F P RF N P+ + L F +G Sbjct: 380 SIGEFAVDKGTHVIINLWALHHNEKEWHQP-DQFMPERFLNPAGTQLISPSLSYLPFGAG 438 Query: 301 PRSCIGQSFAMIEAKAVIAVILQRFSFSL 215 PRSCIG+ A E ++A +LQRF + Sbjct: 439 PRSCIGEILARQELFLIMAWLLQRFDLEV 467
>CP52W_CANAP (Q12573) Cytochrome P450 52E2 (EC 1.14.14.-) (CYPLIIE2)| Length = 519 Score = 72.0 bits (175), Expect = 1e-12 Identities = 52/157 (33%), Positives = 78/157 (49%), Gaps = 12/157 (7%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGS---EVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAG 488 L +PE ++LRE V+ + GS E PT + L + ++ + E LRL+ V L R+A Sbjct: 328 LGAYPEVYDELREAVIADFGSADAEPPTFEQLKQCKVLQNVIREVLRLHPNVPLNFREAI 387 Query: 487 SD--LEVGG-------IKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGK 335 +D GG I VP+G + + R+ +WG D+ F+P R+ N A Sbjct: 388 ADTTFPTGGGPNGDQPIFVPKGQKVFYATYVMQRNAGIWGPDSTSFRPDRW-NEPREALA 446 Query: 334 HPNALLSFSSGPRSCIGQSFAMIEAKAVIAVILQRFS 224 + F+ GPR C+GQ FA+ EA + I Q FS Sbjct: 447 SGWDYIPFNGGPRICLGQQFALTEASYTLVRICQEFS 483
>CP6A9_DROME (Q27594) Cytochrome P450 6a9 (EC 1.14.-.-) (CYPVIA9)| Length = 504 Score = 71.6 bits (174), Expect = 2e-12 Identities = 45/154 (29%), Positives = 84/154 (54%), Gaps = 6/154 (3%) Frame = -1 Query: 658 LSTHPEWQEKLR---EEVLRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAG 488 L+ H + Q+++R +EV+ + E+ M + ++L + + ETLRLY + ++ R+ Sbjct: 324 LAQHQDIQDRVRKECQEVIGKYNGEITYESMKDMVYL-DQVISETLRLYTVLPVLNRECL 382 Query: 487 SDLEVGG---IKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALL 317 D EV G + +G + IP +HRD++++ + N F P F + + L Sbjct: 383 EDYEVPGHPKYVIKKGMPVLIPCGAMHRDEKLYA-NPNTFNPDNFSPERVKE-RDSVEWL 440 Query: 316 SFSSGPRSCIGQSFAMIEAKAVIAVILQRFSFSL 215 F GPR+CIG F ++A++ +A+++ RF FS+ Sbjct: 441 PFGDGPRNCIGMRFGQMQARSGLALLINRFKFSV 474
>C97B1_PEA (Q43078) Cytochrome P450 97B1 (EC 1.14.-.-) (P450 97A2)| Length = 552 Score = 71.6 bits (174), Expect = 2e-12 Identities = 52/166 (31%), Positives = 78/166 (46%), Gaps = 29/166 (17%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTGDMLNKLHLVNMFLLETLRLY-APVSLIQRKAGSD 482 L+ +P+ +K + EV G PT ++L KL + + ++ETLRLY P LI+R D Sbjct: 378 LAQNPDKMKKAQAEVDLVLGMGKPTFELLKKLEYIRLIVVETLRLYPQPPLLIRRSLKPD 437 Query: 481 LEVGGIK-------VPEGTVLTIPIATIHRDKEVWGEDANEFKPMRF------ENGVARA 341 + GG K +P GT + I + +HR W + N+F+P RF E A Sbjct: 438 VLPGGHKGDKDGYTIPAGTDVFISVYNLHRSPYFW-DRPNDFEPERFLVQNNNEEVEGWA 496 Query: 340 GKHPN---------------ALLSFSSGPRSCIGQSFAMIEAKAVI 248 G P+ A L F GPR C+G FA++E+ + Sbjct: 497 GFDPSRSPGALYPNEIISDFAFLPFGGGPRKCVGDQFALMESTVAL 542
>CP6A2_DROME (P33270) Cytochrome P450 6a2 (EC 1.14.-.-) (CYPVIA2) (P450-B1)| Length = 506 Score = 71.6 bits (174), Expect = 2e-12 Identities = 50/154 (32%), Positives = 82/154 (53%), Gaps = 6/154 (3%) Frame = -1 Query: 658 LSTHPEWQEKLREE---VLRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAG 488 L+ + + Q++LR E VL E ++ T + + + +N + ETLRLY V ++RKA Sbjct: 326 LAQNQDIQDRLRNEIQTVLEEQEGQL-TYESIKAMTYLNQVISETLRLYTLVPHLERKAL 384 Query: 487 SDLEVGG---IKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALL 317 +D V G + + +GT + IP HRD++++ + F P RF A + L Sbjct: 385 NDYVVPGHEKLVIEKGTQVIIPACAYHRDEDLY-PNPETFDPERFSPEKV-AARESVEWL 442 Query: 316 SFSSGPRSCIGQSFAMIEAKAVIAVILQRFSFSL 215 F GPR+CIG F ++A+ +A I+ RF S+ Sbjct: 443 PFGDGPRNCIGMRFGQMQARIGLAQIISRFRVSV 476
>C71AO_ARATH (Q9STK9) Cytochrome P450 71A24 (EC 1.14.-.-)| Length = 486 Score = 71.6 bits (174), Expect = 2e-12 Identities = 47/161 (29%), Positives = 78/161 (48%), Gaps = 2/161 (1%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTG-DMLNKLHLVNMFLLETLRLYAPVSL-IQRKAGS 485 L H E ++L+EEV C + D L + + + ETLRL+ P+ L + ++ Sbjct: 307 LLCHHECLDRLQEEVRMVCKDKSGVSEDDLQDMKYLKAVIKETLRLHPPLPLMVPHESTH 366 Query: 484 DLEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSS 305 D+++ +P GT + I I R+ WG DA EF+P R N L+ F + Sbjct: 367 DVKLRDYHIPAGTHVMINAWAIGREAATWGPDAEEFRPERHLNSYVDYRGQDTELVPFGA 426 Query: 304 GPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVHAPMDV 182 G R C SFA++ + V+A ++ +F ++L + DV Sbjct: 427 GRRICPAISFAVVLDEVVLANLVHQFDWTLPEESTEYQTDV 467
>CP21A_HUMAN (P08686) Cytochrome P450 21 (EC 1.14.99.10) (Cytochrome P450 XXI)| (Steroid 21-hydroxylase) (21-OHase) (P450-C21) (P-450c21) (P450-C21B) Length = 494 Score = 71.2 bits (173), Expect = 2e-12 Identities = 53/148 (35%), Positives = 76/148 (51%), Gaps = 6/148 (4%) Frame = -1 Query: 649 HPEWQEKLREEVLRECG-----SEVPTGDMLNKLHLVNMFLLETLRLYAPVSL-IQRKAG 488 HPE Q++L+EE+ E G S VP D +L L+N + E LRL V L + + Sbjct: 310 HPEIQQRLQEELDHELGPGASSSRVPYKDRA-RLPLLNATIAEVLRLRPVVPLALPHRTT 368 Query: 487 SDLEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFS 308 + G +PEGTV+ + H D+ VW E +EF P RF GK+ A L+F Sbjct: 369 RPSSISGYDIPEGTVIIPNLQGAHLDETVW-ERPHEFWPDRF----LEPGKNSRA-LAFG 422 Query: 307 SGPRSCIGQSFAMIEAKAVIAVILQRFS 224 G R C+G+ A +E V+ +LQ F+ Sbjct: 423 CGARVCLGEPLARLELFVVLTRLLQAFT 450
>C4AC2_DROME (Q9VMS8) Probable cytochrome P450 4ac2 (EC 1.14.-.-) (CYPIVAC2)| Length = 497 Score = 71.2 bits (173), Expect = 2e-12 Identities = 49/148 (33%), Positives = 81/148 (54%), Gaps = 4/148 (2%) Frame = -1 Query: 658 LSTHPEWQEKLREEV--LRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGS 485 L+ H + Q+K EE+ L + ++ N+L + + E+LRL+ V I R+ Sbjct: 320 LALHEDVQKKCYEEIKYLPDDSDDISVFQF-NELVYMECVIKESLRLFPSVPFIGRRCVE 378 Query: 484 DLEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRF--ENGVARAGKHPNALLSF 311 + V G+ +P+ T + I + I RD + + F+P RF EN V R HP A + F Sbjct: 379 EGVVNGLIMPKNTQINIHLYEIMRDARHFS-NPKMFQPDRFFPENTVNR---HPFAFVPF 434 Query: 310 SSGPRSCIGQSFAMIEAKAVIAVILQRF 227 S+G R+CIGQ FA++E K ++A +++ F Sbjct: 435 SAGQRNCIGQKFAILEIKVLLAAVIRNF 462
>C71B8_ARATH (P58048) Cytochrome P450 71B8 (EC 1.14.-.-)| Length = 506 Score = 71.2 bits (173), Expect = 2e-12 Identities = 51/152 (33%), Positives = 77/152 (50%), Gaps = 4/152 (2%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECG--SEVPTGDMLNKLHLVNMFLLETLRLYAP-VSLIQRKAG 488 L+ HP +KLREE+ G E T + L K+ + + + ET RL+ P L+ R+ Sbjct: 319 LTRHPRVMKKLREEIRATLGPNKERITEEDLEKVEYLKLVIKETFRLHPPGPFLLPRQVM 378 Query: 487 SDLEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFEN-GVARAGKHPNALLSF 311 SD+E+ G +P+ + I I RD + W + EF P RF N + G+H LL F Sbjct: 379 SDIEIQGYHIPKNAHIKISTYAIGRDPKCW-TNPEEFNPERFANTSINYKGQH-YELLPF 436 Query: 310 SSGPRSCIGQSFAMIEAKAVIAVILQRFSFSL 215 +G RSC G + + + + IL F +SL Sbjct: 437 GAGRRSCPGMTLGITILELGLLNILYYFDWSL 468
>CP21A_BOVIN (P00191) Cytochrome P450 21 (EC 1.14.99.10) (Cytochrome P450 XXI)| (Steroid 21-hydroxylase) (21-OHase) (P450-C21) (P-450c21) Length = 496 Score = 71.2 bits (173), Expect = 2e-12 Identities = 52/152 (34%), Positives = 76/152 (50%), Gaps = 5/152 (3%) Frame = -1 Query: 649 HPEWQEKLREEVLRECGSEVPTGDMLNK----LHLVNMFLLETLRLYAPVSL-IQRKAGS 485 HPE Q +L+EE+ RE G + K L L+N + E LRL V L + + Sbjct: 309 HPEIQRRLQEELDRELGPGASCSRVTYKDRARLPLLNATIAEVLRLRPVVPLALPHRTTR 368 Query: 484 DLEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSS 305 + G +PEG V+ + H D+ VW E +EF+P RF G +P+AL +F Sbjct: 369 PSSIFGYDIPEGMVVIPNLQGAHLDETVW-EQPHEFRPDRF----LEPGANPSAL-AFGC 422 Query: 304 GPRSCIGQSFAMIEAKAVIAVILQRFSFSLSP 209 G R C+G+S A +E V+ +LQ F+ P Sbjct: 423 GARVCLGESLARLELFVVLLRLLQAFTLLPPP 454
>CP52B_CANTR (P30607) Cytochrome P450 52A2 (EC 1.14.14.-) (CYPLIIA2)| (Alkane-inducible P450-ALK2) Length = 522 Score = 71.2 bits (173), Expect = 2e-12 Identities = 56/174 (32%), Positives = 83/174 (47%), Gaps = 18/174 (10%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGS------EVPTGDMLNKLHLVNMFLLETLRLYAPV----- 512 L+ P KLREE+ + G E + + L + L E LRLY V Sbjct: 334 LARTPRVANKLREEIEDKFGLGQDARVEEISFESLKSCEYLKAVLNECLRLYPSVPQNFR 393 Query: 511 -----SLIQRKAGSDLEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMR-FENGV 350 + + R G D + + V +G + + HR+K+++GEDA EF+P R FE Sbjct: 394 VATRNTTLPRGGGKD-GLSPVLVRKGQTVMYSVYAAHRNKQIYGEDALEFRPERWFEPET 452 Query: 349 ARAGKHPNALLSFSSGPRSCIGQSFAMIEAKAVIAVILQRFS-FSLSPKYVHAP 191 + G A L F+ GPR C+GQ FA+ EA V +LQ FS ++ P ++P Sbjct: 453 KKLGW---AFLPFNGGPRICLGQQFALTEASYVTVRLLQEFSHLTMDPNTEYSP 503
>CP52H_CANTR (P30610) Cytochrome P450 52A8 (EC 1.14.14.-) (CYPLIIA8)| (Alkane-inducible P450-ALK5) Length = 517 Score = 71.2 bits (173), Expect = 2e-12 Identities = 58/179 (32%), Positives = 85/179 (47%), Gaps = 17/179 (9%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGS------EVPTGDMLNKLHLVNMFLLETLRLYAPV----- 512 L+ +P KLRE+V + G E T + L + + FL ETLR+Y V Sbjct: 329 LARNPHIWAKLREDVESQFGLGEQSRIEEITFESLKRCGYLKAFLNETLRVYPSVPRNFR 388 Query: 511 -----SLIQRKAGSDLEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVA 347 + + R GSD + V +G ++ I + H D +G+DA EF+P R+ Sbjct: 389 IATKNTTLPRGGGSDGN-SPVLVKKGEAVSYGINSTHLDPVYYGDDAAEFRPERWNEPST 447 Query: 346 RAGKHPNALLSFSSGPRSCIGQSFAMIEAKAVIAVILQRF-SFSLSPKYVHAPMDVITL 173 R K A L F+ GPR C+GQ FA+ EA V+ + Q F + L P V+ P + L Sbjct: 448 R--KLGWAYLPFNGGPRICLGQQFALTEAGYVLVRLAQSFDTLELKPPVVYPPKRLTNL 504
>CP17A_FELCA (Q9GMC8) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 71.2 bits (173), Expect = 2e-12 Identities = 51/149 (34%), Positives = 80/149 (53%), Gaps = 4/149 (2%) Frame = -1 Query: 649 HPEWQEKLREEVLRECG-SEVPTGDMLNKLHLVNMFLLETLRLYAPVS--LIQRKAGSDL 479 HP+ +KL+EE+ + G S PT N+L L+ + E LR+ PV+ LI KA D Sbjct: 321 HPQLYKKLQEEIDQNIGFSRTPTMSDRNQLILLEATIREVLRI-RPVAPTLIPHKAIMDS 379 Query: 478 EVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPN-ALLSFSSG 302 +G V +GT + I + +H +++ W ++F P RF + P+ + L F +G Sbjct: 380 SIGEFAVDKGTNVIINLWALHHNEKEWYRP-DQFMPERFLDPTRSQLISPSLSYLPFGAG 438 Query: 301 PRSCIGQSFAMIEAKAVIAVILQRFSFSL 215 PRSC+G+S A E +A +LQRF + Sbjct: 439 PRSCLGESLARQEVFLFMAWLLQRFDLEV 467
>C71AN_ARATH (Q9STL0) Cytochrome P450 71A23 (EC 1.14.-.-)| Length = 483 Score = 71.2 bits (173), Expect = 2e-12 Identities = 44/148 (29%), Positives = 74/148 (50%), Gaps = 2/148 (1%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLREC-GSEVPTGDMLNKLHLVNMFLLETLRLYAPVSL-IQRKAGS 485 L HP +KL+EEV C G + D + + + + E LRL+ PV L + ++ Sbjct: 305 LLRHPTCLKKLQEEVRTICKGKSSVSEDDIQGMEYLKAVVKEALRLHPPVPLMVPHQSTQ 364 Query: 484 DLEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSS 305 D+ + +P GT + + + + R+ WG DANEF+P R + L+ F + Sbjct: 365 DVRLRDNHIPAGTQVIVNLWAVGREAATWGPDANEFRPERHLESPSDFRGQDFELIPFGA 424 Query: 304 GPRSCIGQSFAMIEAKAVIAVILQRFSF 221 G R C G SFA++ + V+A ++ F + Sbjct: 425 GRRMCPGISFAVVLNEVVLANLVHGFDW 452
>C6A17_DROME (Q9V770) Probable cytochrome P450 6a17 (EC 1.14.-.-) (CYPVIA17)| Length = 501 Score = 70.9 bits (172), Expect = 3e-12 Identities = 48/164 (29%), Positives = 85/164 (51%), Gaps = 4/164 (2%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVP--TGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGS 485 L+ + + Q+KLREE+ G T + + ++ + ++ETLR Y ++ + R + Sbjct: 320 LARNQDVQDKLREEIGNVFGKHNKEFTYEGIKEMKYLEQVVMETLRKYPVLAHLTRMTDT 379 Query: 484 DLEVGGIK--VPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSF 311 D K + +GT++ IP IH D +++ E FKP RF + A + L F Sbjct: 380 DFSPEDPKYFIAKGTIVVIPALGIHYDPDIYPEP-EIFKPERFTDEEI-AARPSCTWLPF 437 Query: 310 SSGPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVHAPMDVI 179 GPR+CIG F M++ +A +++ + FS+SP+ PM ++ Sbjct: 438 GEGPRNCIGLRFGMMQTCVGLAYLIRGYKFSVSPE-TQIPMKIV 480
>CP17A_RAT (P11715) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 507 Score = 70.9 bits (172), Expect = 3e-12 Identities = 49/153 (32%), Positives = 82/153 (53%), Gaps = 7/153 (4%) Frame = -1 Query: 649 HPEWQEKLREEVLRECG-SEVPTGDMLNKLHLVNMFLLETLRLYAPVS--LIQRKAGSDL 479 +PE ++K+++E+ + G S PT + + L ++ + E LR+ PV+ LI KA D Sbjct: 320 NPEVKKKIQKEIDQYVGFSRTPTFNDRSHLLMLEATIREVLRI-RPVAPMLIPHKANVDS 378 Query: 478 EVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKH----PNALLSF 311 +G VP+ T + + + +H D+ W + ++F P RF + G H + L F Sbjct: 379 SIGEFTVPKDTHVVVNLWALHHDENEW-DQPDQFMPERF---LDPTGSHLITPTQSYLPF 434 Query: 310 SSGPRSCIGQSFAMIEAKAVIAVILQRFSFSLS 212 +GPRSCIG++ A E A++LQRF +S Sbjct: 435 GAGPRSCIGEALARQELFVFTALLLQRFDLDVS 467
>CP17A_MOUSE (P27786) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 507 Score = 70.9 bits (172), Expect = 3e-12 Identities = 49/150 (32%), Positives = 80/150 (53%), Gaps = 4/150 (2%) Frame = -1 Query: 649 HPEWQEKLREEVLRECG-SEVPTGDMLNKLHLVNMFLLETLRLYAPVS--LIQRKAGSDL 479 +PE + K+++E+ + G S P+ + L ++ + E LR+ PV+ LI KA D Sbjct: 320 NPEVKRKIQKEIDQYVGFSRTPSFNDRTHLLMLEATIREVLRI-RPVAPLLIPHKANIDS 378 Query: 478 EVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPN-ALLSFSSG 302 +G +P+ T + I + +H DK W + + F P RF + P + L F +G Sbjct: 379 SIGEFAIPKDTHVIINLWALHHDKNEW-DQPDRFMPERFLDPTGSHLITPTPSYLPFGAG 437 Query: 301 PRSCIGQSFAMIEAKAVIAVILQRFSFSLS 212 PRSCIG++ A E +A++LQRF F +S Sbjct: 438 PRSCIGEALARQELFIFMALLLQRFDFDVS 467
>C71A1_PERAE (P24465) Cytochrome P450 71A1 (EC 1.14.-.-) (CYPLXXIA1) (ARP-2)| Length = 471 Score = 70.5 bits (171), Expect = 4e-12 Identities = 49/151 (32%), Positives = 79/151 (52%), Gaps = 3/151 (1%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTGDM-LNKLHLVNMFLLETLRLY--APVSLIQRKAG 488 L HP+ EK ++EV R G + + L++LH + + + ETLRL+ AP+ L+ R++ Sbjct: 320 LIKHPDVMEKAQQEVRRVVGKKAKVEEEDLHQLHYLKLIIKETLRLHPVAPL-LVPREST 378 Query: 487 SDLEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFS 308 D+ + G +P T + I I RD + W E+A EF P RF N L+ F Sbjct: 379 RDVVIRGYHIPAKTRVFINAWAIGRDPKSW-ENAEEFLPERFVNNSVDFKGQDFQLIPFG 437 Query: 307 SGPRSCIGQSFAMIEAKAVIAVILQRFSFSL 215 +G R C G +F + + +A +L F++ L Sbjct: 438 AGRRGCPGIAFGISSVEISLANLLYWFNWEL 468
>CP2L1_PANAR (Q27712) Cytochrome P450 2L1 (EC 1.14.14.1) (CYPIIL1)| Length = 492 Score = 70.5 bits (171), Expect = 4e-12 Identities = 52/157 (33%), Positives = 80/157 (50%), Gaps = 6/157 (3%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTGDM-----LNKLHLVNMFLLETLRLYAPVSL-IQR 497 L +PE Q K++ RE + VP G + +KL + E R+ + V L + Sbjct: 314 LMKYPEVQAKIQ----REIDAAVPRGTLPSLEHKDKLAYFEATIHEVHRIVSLVPLGVSH 369 Query: 496 KAGSDLEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALL 317 D E+ G ++P+GTV+ + HRD W E NEF P F + + K + L+ Sbjct: 370 YTNQDTELAGYRLPKGTVVMSHLECCHRDPSYW-EKPNEFYPEHFLDDQGKFVKREH-LV 427 Query: 316 SFSSGPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPK 206 +FS G R C+G+S A +E ++ ILQ F+FS +PK Sbjct: 428 NFSVGRRVCVGESLARMELFVFLSAILQNFTFS-APK 463
>C82A1_PEA (Q43068) Cytochrome P450 82A1 (EC 1.14.-.-) (CYPLXXXII) (Fragment)| Length = 544 Score = 70.5 bits (171), Expect = 4e-12 Identities = 54/149 (36%), Positives = 71/149 (47%), Gaps = 5/149 (3%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTGDM-LNKLHLVNMFLLETLRLYAPVSLIQ-RKAGS 485 L HP EKL+EE+ G E + +NKL ++ + ETLRLY P R+ Sbjct: 356 LLKHPHVLEKLKEELNTYIGKERCVNESDINKLVYLHAIIKETLRLYPPAPFSSPREFTE 415 Query: 484 DLEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRF---ENGVARAGKHPNALLS 314 D +GG + +GT L + IHRD VW D EFKP RF V G++ LL Sbjct: 416 DCTIGGYHIKKGTRLMPNLWKIHRDPSVW-PDPLEFKPERFLSTHKDVDVRGQN-FELLP 473 Query: 313 FSSGPRSCIGQSFAMIEAKAVIAVILQRF 227 F SG R C G S + ++A L F Sbjct: 474 FGSGRRMCAGMSLGLHMVHYILANFLHSF 502
>CP27B_HUMAN (O15528) 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial| precursor (EC 1.14.13.13) (Cytochrome P450 subfamily XXVIIB polypeptide 1) (Cytochrome p450 27B1) (Calcidiol 1-monooxygenase) (25-OHD-1 alpha-hydroxylase) (25-hydroxyvitamin D(3) Length = 508 Score = 70.5 bits (171), Expect = 4e-12 Identities = 51/153 (33%), Positives = 72/153 (47%), Gaps = 3/153 (1%) Frame = -1 Query: 658 LSTHPEWQEKLREEV---LRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAG 488 LS HPE Q L E+ L S P+ +L++L L+ + E LRLY V R Sbjct: 333 LSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLLKAVVKEVLRLYPVVPGNSRVPD 392 Query: 487 SDLEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFS 308 D+ VG +P+ T++T+ RD + E N F+P R+ HP A L F Sbjct: 393 KDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEP-NSFRPARWLG--EGPTPHPFASLPFG 449 Query: 307 SGPRSCIGQSFAMIEAKAVIAVILQRFSFSLSP 209 G RSC+G+ A +E + +A IL F P Sbjct: 450 FGKRSCMGRRLAELELQMALAQILTHFEVQPEP 482
>CP191_PIG (Q29624) Cytochrome P450 19 type I (EC 1.14.14.1) (Aromatase)| (CYPXIXA1) (Estrogen synthetase) (P-450AROM) Length = 503 Score = 70.5 bits (171), Expect = 4e-12 Identities = 44/144 (30%), Positives = 71/144 (49%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSDL 479 ++ HP+ +E+L +E+ G D + KL +V F+ E++R V L+ RKA D Sbjct: 322 IAKHPQVEEELMKEIQTVVGERDIRNDDMQKLEVVENFIYESMRYQPVVDLVMRKALEDD 381 Query: 478 EVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSGP 299 + G V +GT + + I +HR + + NEF F V P F GP Sbjct: 382 VIDGYPVKKGTNIILNIGRMHRLE--FFPKPNEFTLENFAKNVPYRYFQP-----FGFGP 434 Query: 298 RSCIGQSFAMIEAKAVIAVILQRF 227 R+C G+ AM+ K + ++L+RF Sbjct: 435 RACAGKYIAMVMMKVTLVILLRRF 458
>C6A18_DROME (Q9VB31) Probable cytochrome P450 6a18 (EC 1.14.-.-) (CYPVIA18)| Length = 507 Score = 70.5 bits (171), Expect = 4e-12 Identities = 49/153 (32%), Positives = 80/153 (52%), Gaps = 6/153 (3%) Frame = -1 Query: 658 LSTHPEWQEKLREEV--LRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGS 485 L+ +P Q+K+R E+ + E + T + + L ++ + ETLR Y V + R A Sbjct: 326 LAKNPSIQDKVRAELGQVLEQHDQKFTYECIKDLKYLDQVINETLRHYTIVPNVDRVAAK 385 Query: 484 DLEVGG---IKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPN-ALL 317 V G + G + IP + IH D ++ E NEF+P RF + K P+ A L Sbjct: 386 RFVVPGNPKFVIEAGQSVIIPSSAIHHDPSIYPEP-NEFRPERFSP--EESAKRPSVAWL 442 Query: 316 SFSSGPRSCIGQSFAMIEAKAVIAVILQRFSFS 218 F GPR+CIG F ++A+ +A++++ F+FS Sbjct: 443 PFGEGPRNCIGLRFGQMQARIGLAMLIKNFTFS 475
>C71AQ_ARATH (Q9STK7) Cytochrome P450 71A26 (EC 1.14.-.-)| Length = 489 Score = 70.1 bits (170), Expect = 6e-12 Identities = 44/151 (29%), Positives = 74/151 (49%), Gaps = 2/151 (1%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTGDM-LNKLHLVNMFLLETLRLYAPVSL-IQRKAGS 485 L HP+ ++L+EEV C + + + + + + E LRL+ P+ L + ++ Sbjct: 307 LLRHPKCLKRLQEEVRTICKDKSSVSEEEIQNMSYLKAVIKEALRLHPPLPLMVPHESTQ 366 Query: 484 DLEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSS 305 D+ +G +P GT + I I R+ WG D EF+P R + L+ F S Sbjct: 367 DVRLGDHHIPAGTQVLINAWAIGREAATWGPDVEEFRPERHLDSSVDYRGQAFELIPFGS 426 Query: 304 GPRSCIGQSFAMIEAKAVIAVILQRFSFSLS 212 G R C SFA++ + V+A ++ RF + LS Sbjct: 427 GRRICPAISFAVVLNEVVLANLVHRFDWRLS 457
>CP6D5_DROME (Q9VFP1) Probable cytochrome P450 6d5 (EC 1.14.-.-) (CYPVID5)| Length = 508 Score = 70.1 bits (170), Expect = 6e-12 Identities = 56/180 (31%), Positives = 86/180 (47%), Gaps = 8/180 (4%) Frame = -1 Query: 658 LSTHPEWQEKLREEV---LRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAG 488 L+ +PE EK +E+V + + G ++ T D ++ + + +LET R Y + L+ R Sbjct: 330 LTQNPEVMEKAKEDVRSAIEKHGGKL-TYDAISDMKYLEACILETARKYPALPLLNRICT 388 Query: 487 SDLEVGGIK--VPEGTVLTIPIATIHRDKEVWGEDANEFKPMRF-ENGVARAGKHPNALL 317 D V K + +GT + I + +HRD+E + D +KP R+ ENG A L Sbjct: 389 KDYPVPDSKLVIQKGTPIIISLIGMHRDEEYF-PDPLAYKPERYLENGKDYTQA---AYL 444 Query: 316 SFSSGPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVHAPMDV--ITLRPKFGLPMIL 143 F GPR CIG + K IA +L F + + V I L PK G+P+ L Sbjct: 445 PFGEGPRMCIGARMGKVNVKIAIAKVLSNFDLEIRKEKCEIEFGVYGIPLMPKSGVPVRL 504
>CP2D1_RAT (P10633) Cytochrome P450 2D1 (EC 1.14.14.1) (CYPIID1) (P450-DB1)| (P450-CMF1A) (P450-UT-7) (Debrisoquine 4-hydroxylase) Length = 504 Score = 70.1 bits (170), Expect = 6e-12 Identities = 47/149 (31%), Positives = 81/149 (54%), Gaps = 4/149 (2%) Frame = -1 Query: 649 HPEWQEKLREEVLRECGSEVPTGDMLNKLHL--VNMFLLETLRL--YAPVSLIQRKAGSD 482 +P+ Q ++++E+ G +V +M ++ H+ N + E R AP++L R D Sbjct: 327 YPDVQRRVQQEIDEVIG-QVRCPEMTDQAHMPYTNAVIHEVQRFGDIAPLNL-PRFTSCD 384 Query: 481 LEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSG 302 +EV +P+GT L I ++++ +D+ VW E + F P F + KH A + FS+G Sbjct: 385 IEVQDFVIPKGTTLIINLSSVLKDETVW-EKPHRFHPEHFLDAQGNFVKH-EAFMPFSAG 442 Query: 301 PRSCIGQSFAMIEAKAVIAVILQRFSFSL 215 R+C+G+ A +E +LQRFSFS+ Sbjct: 443 RRACLGEPLARMELFLFFTCLLQRFSFSV 471
>CP19A_POEGU (Q92112) Cytochrome P450 19A1 (EC 1.14.14.1) (Aromatase) (CYPXIX)| (Estrogen synthetase) (P-450AROM) Length = 509 Score = 69.7 bits (169), Expect = 7e-12 Identities = 45/143 (31%), Positives = 69/143 (48%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSDL 479 ++ HP +E++ E+ G D + L +V F+ E++R V LI RKA D Sbjct: 322 IAEHPTVEEEMMREIETVVGDRDIQSDDMPNLKIVENFIYESMRYQPVVDLIMRKALQDD 381 Query: 478 EVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSGP 299 + G V +GT + + I +H K + NEF FE V P F GP Sbjct: 382 VIDGYPVKKGTNIILNIGRMH--KLEFFPKPNEFSLENFEKNVPSRYFQP-----FGFGP 434 Query: 298 RSCIGQSFAMIEAKAVIAVILQR 230 RSC+G+ AM+ KA++ +L+R Sbjct: 435 RSCVGKFIAMVMMKAILVTLLRR 457
>CP17A_SQUAC (Q92113) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 509 Score = 69.7 bits (169), Expect = 7e-12 Identities = 51/156 (32%), Positives = 81/156 (51%), Gaps = 7/156 (4%) Frame = -1 Query: 649 HPEWQEKLREEVLRECGSE-VPTGDMLNKLHLVNMFLLETLRLYAPVS--LIQRKAGSDL 479 HPE Q+K++EE+ G E P ++ +N + E LR+ PVS LI A +D Sbjct: 324 HPEVQKKIQEEIDSNIGFERTPKMSDKGNMNFLNATIHEILRIQ-PVSPLLIPHVALADS 382 Query: 478 EVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKH----PNALLSF 311 +G +P+GT + I + IH D++ W ++ + F P RF + GK+ + L F Sbjct: 383 SIGDYTIPKGTRVIINLWAIHHDEKEW-KNPDAFDPGRF---LDEDGKYVCSSSESYLPF 438 Query: 310 SSGPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKY 203 +G R C+G+ A +E + ILQRF+ + P Y Sbjct: 439 GAGTRVCLGEMLARMELFLFTSWILQRFTVQVPPGY 474
>CP2D9_MOUSE (P11714) Cytochrome P450 2D9 (EC 1.14.14.1) (CYPIID9)| (P450-16-alpha) (CA) (Testosterone 16-alpha hydroxylase) Length = 504 Score = 69.3 bits (168), Expect = 9e-12 Identities = 48/149 (32%), Positives = 80/149 (53%), Gaps = 4/149 (2%) Frame = -1 Query: 649 HPEWQEKLREEVLRECGSEVPTGDMLNKLHL--VNMFLLETLRL--YAPVSLIQRKAGSD 482 HP+ Q ++++E+ G +V +M ++ H+ N + E R PV+L R D Sbjct: 327 HPDVQRRVQQEIDEVIG-QVRHPEMADQAHMPYTNAVIHEVQRFGDIVPVNL-PRITSHD 384 Query: 481 LEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSG 302 +EV +P+GT+L ++++ +D+ VW E F P F + K P A + FS+G Sbjct: 385 IEVQDFLIPKGTILLPNMSSMLKDESVW-EKPLRFHPEHFLDAQGHFVK-PEAFMPFSAG 442 Query: 301 PRSCIGQSFAMIEAKAVIAVILQRFSFSL 215 RSC+G++ A +E +LQRFSFS+ Sbjct: 443 RRSCLGEALARMELFLFFTCLLQRFSFSV 471
>C6A21_DROME (Q9V774) Probable cytochrome P450 6a21 (EC 1.14.-.-) (CYPVIA21)| Length = 504 Score = 69.3 bits (168), Expect = 9e-12 Identities = 45/157 (28%), Positives = 84/157 (53%), Gaps = 6/157 (3%) Frame = -1 Query: 658 LSTHPEWQEKLR---EEVLRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAG 488 L+ + + Q ++R +EV+ +C E+ M + ++L + + ETLRLY + ++ R+ Sbjct: 324 LAQNQDIQNRVRKECQEVIEKCNGELNYESMKDLVYL-DQVVSETLRLYTVLPVLNRECL 382 Query: 487 SDLEVGG---IKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALL 317 D EV G + +G + IP +HRD++++ + N F P F + + L Sbjct: 383 EDYEVPGHPKYVIKKGMPVLIPCGAMHRDEKLYA-NPNTFNPDNFSPERVKE-RDSVEWL 440 Query: 316 SFSSGPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPK 206 F GPR+CIG F ++A+ +A++++ F FS+ K Sbjct: 441 PFGDGPRNCIGMRFGQMQARIGLALLIKDFKFSVCEK 477
>CP9E2_BLAGE (Q964T2) Cytochrome P450 9e2 (EC 1.14.-.-) (CYPIXE2)| Length = 533 Score = 69.3 bits (168), Expect = 9e-12 Identities = 47/157 (29%), Positives = 82/157 (52%), Gaps = 6/157 (3%) Frame = -1 Query: 658 LSTHPEWQEKLREEV---LRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAG 488 L+T+P+ Q +L++E+ L E ++ T + ++ + ++M + E+LRLY P RK Sbjct: 350 LATNPDVQNRLQDEIDQSLEENDGKL-TYEAIHSMKYLDMVVSESLRLYPPAIFTDRKCV 408 Query: 487 SDLEVG---GIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALL 317 + + + G + IPI IH D + + + +F P RF + + P L Sbjct: 409 KNYRLPMEPSYTLEPGDAVWIPIYAIHHDPKYY-PNPEKFDPERFSDE-NKDNIKPFTYL 466 Query: 316 SFSSGPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPK 206 F SGPR+CIG FA++E+K + +L RF+ + K Sbjct: 467 PFGSGPRNCIGNRFALMESKIALVHLLCRFNLKVVSK 503
>CP193_PIG (P79304) Cytochrome P450 19 type III (EC 1.14.14.1) (Aromatase)| (CYPXIXA3) (Estrogen synthetase) (P-450AROM) Length = 501 Score = 69.3 bits (168), Expect = 9e-12 Identities = 43/144 (29%), Positives = 70/144 (48%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSDL 479 ++ HP+ +E+L +E+ G D + KL +V F+ E++R V + RKA D Sbjct: 320 IANHPQVEEELMKEIYTVVGERDIRNDDMQKLKVVENFIYESMRYQPVVDFVMRKALEDD 379 Query: 478 EVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSGP 299 + G V +GT + + I +HR + + NEF F V P F GP Sbjct: 380 VIDGYPVKKGTNIILNIGRMHRLE--FFPKPNEFTLENFAKNVPYRYFQP-----FGFGP 432 Query: 298 RSCIGQSFAMIEAKAVIAVILQRF 227 R+C G+ AM+ K ++ +L+RF Sbjct: 433 RACAGKYIAMVMMKVILVTLLRRF 456
>CP19A_ORENI (P70091) Cytochrome P450 19A1 (EC 1.14.14.1) (Aromatase) (CYPXIX)| (Estrogen synthetase) (P-450AROM) Length = 522 Score = 69.3 bits (168), Expect = 9e-12 Identities = 42/145 (28%), Positives = 72/145 (49%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSDL 479 L +P + +L +E+ G L+KL ++ F+ E L + V R+A SD Sbjct: 331 LKQNPHVEPQLLQEIDAVVGERQLQNQDLHKLQVMESFIYECLSFHPVVDFTMRRALSDD 390 Query: 478 EVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSGP 299 + G ++ +GT + + +HR + + N+F FEN V R P F SGP Sbjct: 391 IIEGYRISKGTNIILNTGRMHRTE--FFLKGNQFNLEHFENNVPR----PPTFQPFGSGP 444 Query: 298 RSCIGQSFAMIEAKAVIAVILQRFS 224 R+CIG+ AM+ K+++ +L ++S Sbjct: 445 RACIGKHMAMVMMKSILVTLLSQYS 469
>CP17A_PAPHU (Q9GLD2) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 69.3 bits (168), Expect = 9e-12 Identities = 50/149 (33%), Positives = 80/149 (53%), Gaps = 4/149 (2%) Frame = -1 Query: 649 HPEWQEKLREEVLRECG-SEVPTGDMLNKLHLVNMFLLETLRLYAPVS--LIQRKAGSDL 479 +P+ ++KL E + + G S PT N+L L+ + E LR+ PV+ LI KA D Sbjct: 321 NPQVKKKLYEGIDQNVGFSRTPTISDRNRLLLLEATIREVLRI-RPVAPMLIPHKANVDS 379 Query: 478 EVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPN-ALLSFSSG 302 +G V +GT + I + +H +++ W + ++F P RF N P+ + L F +G Sbjct: 380 SIGEFAVDKGTHVIINLWALHHNEKEWHQP-DQFMPERFLNPAGTQLISPSLSYLPFGAG 438 Query: 301 PRSCIGQSFAMIEAKAVIAVILQRFSFSL 215 PRSCIG+ A E ++A +LQRF + Sbjct: 439 PRSCIGEILARQELFLIMAWLLQRFDLEV 467
>CP52D_CANMA (P16141) Cytochrome P450 52A4 (EC 1.14.14.-) (CYPLIIA4)| (Alkane-inducible P450-ALK3-A) (P450-CM2) Length = 537 Score = 69.3 bits (168), Expect = 9e-12 Identities = 53/161 (32%), Positives = 77/161 (47%), Gaps = 17/161 (10%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGS------EVPTGDMLNKLHLVNMFLLETLRLYAPV----- 512 LS +P EKL+EE+ G+ E T + L + + E LR+Y V Sbjct: 349 LSRNPTVFEKLKEEIHNRFGAKEDARVEEITFESLKLCEYLKACVNEALRVYPSVPHNFR 408 Query: 511 -----SLIQRKAGSDLEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMR-FENGV 350 + + R G D + I + +G + I+ HRD ++GEDAN F+P R FE Sbjct: 409 VATRNTTLPRGGGKD-GMSPIAIKKGQNVMYTISATHRDPSIYGEDANVFRPERWFEPET 467 Query: 349 ARAGKHPNALLSFSSGPRSCIGQSFAMIEAKAVIAVILQRF 227 + G A + F+ GPR C+GQ FA+ EA V +LQ F Sbjct: 468 RKLGW---AYVPFNGGPRICLGQQFALTEASYVTVRLLQEF 505
>CP51A_BOVIN (Q4PJW3) Cytochrome P450 51A1 (EC 1.14.13.70) (CYPLI) (P450LI)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (LDM) (P450-14DM) (P45014DM) Length = 502 Score = 69.3 bits (168), Expect = 9e-12 Identities = 46/147 (31%), Positives = 73/147 (49%), Gaps = 2/147 (1%) Frame = -1 Query: 637 QEKLREEVLRECGSEVP--TGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSDLEVGGI 464 QEK E CG +P T D L L+L++ + ETLRL P+ + R A + L V G Sbjct: 333 QEKCFLEQKTVCGENLPPLTYDQLKDLNLLDRCIKETLRLRPPIMTMMRLAKTPLTVAGY 392 Query: 463 KVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSGPRSCIG 284 +P G + + R K+ W E +F P R+ +G+ A + F +G CIG Sbjct: 393 TIPPGHQVCVSPTVNQRLKDSWVERL-DFNPDRYLEDSPASGE-KFAYVPFGAGRHRCIG 450 Query: 283 QSFAMIEAKAVIAVILQRFSFSLSPKY 203 ++FA ++ K + + +L+ + F L Y Sbjct: 451 ENFAYVQIKTIWSTMLRLYEFDLIDGY 477
>C86A1_ARATH (P48422) Cytochrome P450 86A1 (EC 1.14.-.-) (CYPLXXXVI)| (P450-dependent fatty acid omega-hydroxylase) Length = 513 Score = 68.9 bits (167), Expect = 1e-11 Identities = 53/170 (31%), Positives = 81/170 (47%), Gaps = 4/170 (2%) Frame = -1 Query: 637 QEKLREEVLRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSL-IQRKAGSDLEVGGIK 461 QEK EE L D ++L + L ETLRLY V + D+ G Sbjct: 345 QEKWTEEPLEF--------DEADRLVYLKAALAETLRLYPSVPQDFKYVVDDDVLPDGTF 396 Query: 460 VPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPN---ALLSFSSGPRSC 290 VP G+ +T I +I R K +WGED EF+P R+ + P ++F++GPR+C Sbjct: 397 VPRGSTVTYSIYSIGRMKTIWGEDCLEFRPERWLTADGERFETPKDGYKFVAFNAGPRTC 456 Query: 289 IGQSFAMIEAKAVIAVILQRFSFSLSPKYVHAPMDVITLRPKFGLPMILK 140 +G+ A + K+V + +L R+ P + +TL K GL + L+ Sbjct: 457 LGKDLAYNQMKSVASAVLLRYRVFPVPGHRVEQKMSLTLFMKNGLRVYLQ 506
>CP2DG_CAVPO (Q64403) Cytochrome P450 2D16 (EC 1.14.14.1) (CYPIID16)| Length = 500 Score = 68.9 bits (167), Expect = 1e-11 Identities = 47/148 (31%), Positives = 76/148 (51%), Gaps = 3/148 (2%) Frame = -1 Query: 649 HPEWQEKLREEVLRECGSEVPTGDMLNKLHL--VNMFLLETLRLYAPVSL-IQRKAGSDL 479 HP+ Q ++EE+ G +V +M ++ H+ N + E R V + + D Sbjct: 327 HPDVQRHVQEEIDEVIG-QVRCPEMADQAHMPFTNAVIHEVQRFADIVPMGVPHMTSRDT 385 Query: 478 EVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSGP 299 EV G +P+GT+L ++++ +D+ VW E F P F + R K A + FS+GP Sbjct: 386 EVQGFLIPKGTMLFTNLSSVLKDETVW-EKPLHFHPGHFLDAEGRFVKR-EAFMPFSAGP 443 Query: 298 RSCIGQSFAMIEAKAVIAVILQRFSFSL 215 R C+G+ A +E +LQRFSFS+ Sbjct: 444 RICLGEPLARMELFLFFTSLLQRFSFSV 471
>CP2D3_RAT (P12938) Cytochrome P450 2D3 (EC 1.14.14.1) (CYPIID3) (P450-DB3)| (Debrisoquine 4-hydroxylase) Length = 500 Score = 68.9 bits (167), Expect = 1e-11 Identities = 46/148 (31%), Positives = 78/148 (52%), Gaps = 3/148 (2%) Frame = -1 Query: 649 HPEWQEKLREEVLRECGSEVPTGDMLNKLHL--VNMFLLETLRLYAPVSL-IQRKAGSDL 479 HP+ Q ++++E+ G +V +M ++ H+ N + E R V + + K D+ Sbjct: 327 HPDVQCRVQQEIDEVIG-QVRHPEMADQAHMPFTNAVIHEVQRFADIVPMNLPHKTSRDI 385 Query: 478 EVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSGP 299 EV G +P+GT L ++++ +D+ VW E F P F + KH A + FS+G Sbjct: 386 EVQGFLIPKGTTLIPNLSSVLKDETVW-EKPLRFHPEHFLDAQGNFVKH-EAFMPFSAGR 443 Query: 298 RSCIGQSFAMIEAKAVIAVILQRFSFSL 215 R+C+G+ A +E +LQRFSFS+ Sbjct: 444 RACLGEPLARMELFLFFTCLLQRFSFSV 471
>CP51A_PONPY (Q5RE72) Cytochrome P450 51A1 (EC 1.14.13.70) (CYPLI) (P450LI)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (LDM) (P450-14DM) (P45014DM) Length = 503 Score = 68.6 bits (166), Expect = 2e-11 Identities = 45/147 (30%), Positives = 73/147 (49%), Gaps = 2/147 (1%) Frame = -1 Query: 637 QEKLREEVLRECGSEVP--TGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSDLEVGGI 464 QEK E CG +P T D L L+L++ + ETLRL P+ ++ R A + V G Sbjct: 334 QEKCYLEQKTVCGENLPPLTYDQLKDLNLLDRCIKETLRLRPPIMIMMRMARTPQTVAGY 393 Query: 463 KVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSGPRSCIG 284 +P G + + R K+ W E +F P R+ +G+ A + F +G CIG Sbjct: 394 TIPPGHQVCVSPTVNQRLKDSWVERL-DFNPDRYLQDNPASGE-KFAYVPFGAGRHRCIG 451 Query: 283 QSFAMIEAKAVIAVILQRFSFSLSPKY 203 ++FA ++ K + + +L+ + F L Y Sbjct: 452 ENFAYVQIKTIWSTMLRLYEFDLIDGY 478
>C93B1_GLYEC (P93149) Cytochrome P450 93B1 (EC 1.14.13.87) (Licodione synthase)| ((2S)-flavanone 2-hydroxylase) (Flavone synthase II) (CYP GE-5) Length = 523 Score = 68.6 bits (166), Expect = 2e-11 Identities = 49/150 (32%), Positives = 75/150 (50%), Gaps = 8/150 (5%) Frame = -1 Query: 646 PEWQEKLREEVLRECGSE--VPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSDLEV 473 P +K+REE+ G + V D N L + L ET RL+ PV ++ R+ ++ V Sbjct: 324 PSVLQKVREEIDNVVGKDRLVEESDCPN-LPYLQAILKETFRLHPPVPMVTRRCVAECTV 382 Query: 472 GGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRF------ENGVARAGKHPNALLSF 311 +PE ++L + + +I R+ + W ++ EF+P RF +GV LL F Sbjct: 383 ENYVIPEDSLLFVNVWSIGRNPKFW-DNPLEFRPERFLKLEGDSSGVVDVRGSHFQLLPF 441 Query: 310 SSGPRSCIGQSFAMIEAKAVIAVILQRFSF 221 SG R C G S AM E A++ I+Q F F Sbjct: 442 GSGRRMCPGVSLAMQEVPALLGAIIQCFDF 471
>CP19A_ICTPU (Q92111) Cytochrome P450 19A1 (EC 1.14.14.1) (Aromatase) (CYPXIX)| (Estrogen synthetase) (P-450AROM) Length = 524 Score = 68.6 bits (166), Expect = 2e-11 Identities = 45/145 (31%), Positives = 72/145 (49%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSDL 479 L + E + ++ E+ G L++LH++ F+ E LR + V R+A D Sbjct: 342 LKQNAEVERRILTEIHTVLGDTELQHSHLSQLHVLECFINEALRFHPVVDFSYRRALDDD 401 Query: 478 EVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSGP 299 + G +VP GT + + + +HR E + + A +F F V P F SGP Sbjct: 402 VIEGFRVPRGTNIILNVGRMHRS-EFYPKPA-DFSLDNFNKPVPSRFFQP-----FGSGP 454 Query: 298 RSCIGQSFAMIEAKAVIAVILQRFS 224 RSC+G+ AM+ KAV+ ++L RFS Sbjct: 455 RSCVGKHIAMVMMKAVLLMVLSRFS 479
>CP2DR_MESAU (Q9QYG6) Cytochrome P450 2D27 (EC 1.14.14.-) (CYPIID27)| Length = 500 Score = 68.6 bits (166), Expect = 2e-11 Identities = 48/149 (32%), Positives = 79/149 (53%), Gaps = 4/149 (2%) Frame = -1 Query: 649 HPEWQEKLREEVLRECGSEVPTGDMLNKLHL--VNMFLLETLRL--YAPVSLIQRKAGSD 482 HP+ Q ++++E+ G +V +M ++ + N + E R APV+ I D Sbjct: 327 HPDVQSRVQQEIDDVIG-QVRRPEMADQARMPYTNAVIHEVQRFGDIAPVN-IPHMTSHD 384 Query: 481 LEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSG 302 +EV G +P+GT L ++++ +D+ VW E F P F + R KH A + FS+G Sbjct: 385 VEVQGFLIPKGTTLIPNLSSVLKDETVW-EKPLHFHPEHFLDAQGRFVKH-EAFMPFSAG 442 Query: 301 PRSCIGQSFAMIEAKAVIAVILQRFSFSL 215 R+C+G+ A +E +LQRFSFS+ Sbjct: 443 RRACLGEPLARMELFLFFTCLLQRFSFSV 471
>C71A6_NEPRA (O04164) Cytochrome P450 71A6 (EC 1.14.-.-) (Fragment)| Length = 511 Score = 68.6 bits (166), Expect = 2e-11 Identities = 53/152 (34%), Positives = 78/152 (51%), Gaps = 4/152 (2%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGS--EVPTGDMLNKLHLVNMFLLETLRLYAPVSL-IQRKAG 488 L +P + L++EV GS E+ D L K+ + + E+LRL+APV L + R++ Sbjct: 327 LIKNPRAMKILQKEVRGVAGSKGEIEESD-LEKMPYLKAVMKESLRLHAPVPLLVPREST 385 Query: 487 SDLEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRF-ENGVARAGKHPNALLSF 311 D +V G V GT + I I RD VW E++ F P RF E + G H L+ F Sbjct: 386 RDTKVLGYDVASGTRVLINCWAIGRDSSVW-EESETFLPERFLETSIDYRGMHFE-LIPF 443 Query: 310 SSGPRSCIGQSFAMIEAKAVIAVILQRFSFSL 215 SG R C G +FA + +A ++ +F F L Sbjct: 444 GSGRRGCPGATFAAAIDELALATLVHKFDFKL 475
>CP311_DROME (Q9VYQ7) Probable cytochrome P450 311a1 (EC 1.14.-.-) (CYPCCCXIA1)| Length = 483 Score = 68.6 bits (166), Expect = 2e-11 Identities = 46/151 (30%), Positives = 70/151 (46%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSDL 479 L+ PE Q +LR+E+ E D LN L + + E LRLY V R+ Sbjct: 309 LAKFPETQTRLRKELQDVALDETTDLDALNGLPYLEALIKEVLRLYTIVPTTGRQTTQST 368 Query: 478 EVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSGP 299 E+GG G L I + + DKE + D FKP R+ + + FS GP Sbjct: 369 EIGGRTYCAGVTLWINMYGLAHDKEYY-PDPYAFKPERWLPEDGAVAPPAFSYIPFSGGP 427 Query: 298 RSCIGQSFAMIEAKAVIAVILQRFSFSLSPK 206 CIG+ ++++ K + A +++ F LSP+ Sbjct: 428 HVCIGRRYSLLLMKLLTARLVREFQMELSPE 458
>CP6B6_HELAM (Q95031) Cytochrome P450 6B6 (EC 1.14.14.1) (CYPVIB6)| Length = 504 Score = 68.2 bits (165), Expect = 2e-11 Identities = 50/150 (33%), Positives = 80/150 (53%), Gaps = 6/150 (4%) Frame = -1 Query: 658 LSTHPEWQEKLR---EEVLRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAG 488 L+ P+ Q KL +EVL+ +V T D + ++ +N ETLR+Y+ V +QRKA Sbjct: 321 LALSPDIQNKLIAEVDEVLKANDGKV-TYDTVKEMKYMNKAFDETLRMYSIVEPLQRKAT 379 Query: 487 SDLEVGG--IKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGK-HPNALL 317 D ++ G + + + T++ I IH D + + ++ +F P RF+ GK HP A L Sbjct: 380 RDYKIPGTDVVIEKDTIVLISPRGIHYDPKYY-DNPKQFNPDRFD--AEEVGKRHPCAYL 436 Query: 316 SFSSGPRSCIGQSFAMIEAKAVIAVILQRF 227 F G R+CIG F +++ I IL +F Sbjct: 437 PFGLGQRNCIGMRFGRLQSLLCITKILSKF 466
>CP1A1_MOUSE (P00184) Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1) (P450-P1)| Length = 524 Score = 68.2 bits (165), Expect = 2e-11 Identities = 49/173 (28%), Positives = 83/173 (47%), Gaps = 3/173 (1%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSE-VPTGDMLNKLHLVNMFLLETLRLYAPVSL-IQRKAGS 485 L T+P Q K++EE+ G + P +L + F+LET R + V I Sbjct: 337 LVTNPRVQRKIQEELDTVIGRDRQPRLSDRPQLPYLEAFILETFRHSSFVPFTIPHSTTR 396 Query: 484 DLEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLS-FS 308 D + G +P+G + + ++ D+E+WG D NEF+P RF K + ++ F Sbjct: 397 DTSLNGFYIPKGCCVFVNQWQVNHDRELWG-DPNEFRPERFLTPSGTLDKRLSEKVTLFG 455 Query: 307 SGPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVHAPMDVITLRPKFGLPM 149 G R CIG++ E +A++LQ+ F +SP + + + P +GL + Sbjct: 456 LGKRKCIGETIGRSEVFLFLAILLQQIEFKVSPG------EKVDMTPTYGLTL 502
>C71BU_ARATH (Q9SCN2) Cytochrome P450 71B31 (EC 1.14.-.-)| Length = 498 Score = 68.2 bits (165), Expect = 2e-11 Identities = 49/152 (32%), Positives = 78/152 (51%), Gaps = 4/152 (2%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECG--SEVPTGDMLNKLHLVNMFLLETLRLYAPVS-LIQRKAG 488 L+ HP +KL+EE+ G E T + L K+ +N+ + E+ RL+ P L+ R+ Sbjct: 317 LTRHPRVMKKLQEEIRATLGPNKERITEEDLEKVEYLNLVIKESFRLHPPAPLLLPRETM 376 Query: 487 SDLEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFEN-GVARAGKHPNALLSF 311 SD+E+ G +P+ + I I RD + W + EF P RF N + G+H LL F Sbjct: 377 SDIEIQGYHIPKNAHVKINTYAIGRDPKRW-TNPEEFNPERFLNTSINYKGQH-YELLPF 434 Query: 310 SSGPRSCIGQSFAMIEAKAVIAVILQRFSFSL 215 +G R+C G + + + + IL F +SL Sbjct: 435 GAGRRNCPGMTLGITILELGLLNILYYFDWSL 466
>C71B5_ARATH (O65784) Cytochrome P450 71B5 (EC 1.14.-.-)| Length = 498 Score = 68.2 bits (165), Expect = 2e-11 Identities = 50/152 (32%), Positives = 77/152 (50%), Gaps = 4/152 (2%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECG--SEVPTGDMLNKLHLVNMFLLETLRLYAPVS-LIQRKAG 488 LS HP KL+EE+ G E T + L K+ + M + E RL+ P L+ R Sbjct: 315 LSRHPRVMRKLQEEIRAALGPNKEKITEEDLEKVEYLKMVIEEAFRLHPPAPLLLPRLTM 374 Query: 487 SDLEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRF-ENGVARAGKHPNALLSF 311 SD+ + G +P+ T++ I TI RD + W + +EF P RF +N + G+H LL F Sbjct: 375 SDINIQGYSIPKNTMIQINTYTIGRDPKNWTK-PDEFIPERFVDNPIEYKGQH-FELLPF 432 Query: 310 SSGPRSCIGQSFAMIEAKAVIAVILQRFSFSL 215 +G R C G + + + + +L F +SL Sbjct: 433 GAGRRVCPGMATGITIVELGLLSLLYFFDWSL 464
>C71AR_ARATH (O65438) Cytochrome P450 71A27 (EC 1.14.-.-)| Length = 499 Score = 68.2 bits (165), Expect = 2e-11 Identities = 43/152 (28%), Positives = 80/152 (52%), Gaps = 4/152 (2%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVP-TGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSD 482 L HPE +KL++E+ + T + K++ ++ + E LRL+ L+ R D Sbjct: 315 LMRHPECMKKLQDEINSFSTHNLNVTEKEVEKMNYLHCVIKEGLRLHPSGPLLFRLPSED 374 Query: 481 LEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMR---FENGVARAGKHPNALLSF 311 +++ G + GT + I + R+ +WG DANE++P R +E G R + + F Sbjct: 375 VQLKGYDISAGTHVIINAWALQRNPAIWGLDANEYRPERHFWYEFGFQRT---DSKFVPF 431 Query: 310 SSGPRSCIGQSFAMIEAKAVIAVILQRFSFSL 215 +G R C G F+++ +K +A +++RF++ L Sbjct: 432 GAGRRLCPGIGFSLVLSKLALANLVKRFNWRL 463
>CP192_CARAU (O73686) Cytochrome P450 19 type 2 (EC 1.14.14.1) (Ovarian| aromatase) (CYPXIXA2) (Estrogen synthetase) (P-450AROM) Length = 518 Score = 68.2 bits (165), Expect = 2e-11 Identities = 42/145 (28%), Positives = 70/145 (48%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSDL 479 L +P+ + K+ +E+ L+ H++ F+ E+LR + V R+A D Sbjct: 342 LKQNPDVELKILQEMNAVLAGRSLQHSHLSGFHILESFINESLRFHPVVDFTMRRALDDD 401 Query: 478 EVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSGP 299 + G KV GT + + + +HR + + NEF F+ V P F SGP Sbjct: 402 VIEGYKVKRGTNIILNVGRMHRSE--FFPKPNEFSLDNFQKNVPSRFFQP-----FGSGP 454 Query: 298 RSCIGQSFAMIEAKAVIAVILQRFS 224 RSC+G+ AM+ K+++ +L RFS Sbjct: 455 RSCVGKHMAMVMMKSILVTLLSRFS 479
>CP51A_PIG (O46420) Cytochrome P450 51A1 (EC 1.14.13.70) (CYPLI) (P450LI)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (LDM) (P450-14DM) Length = 503 Score = 68.2 bits (165), Expect = 2e-11 Identities = 45/147 (30%), Positives = 73/147 (49%), Gaps = 2/147 (1%) Frame = -1 Query: 637 QEKLREEVLRECGSEVP--TGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSDLEVGGI 464 QEK E CG ++P T D L L+L++ + ETLRL P+ + R A + V G Sbjct: 334 QEKCYLEQKTVCGEDLPPLTYDQLKDLNLLDRCIKETLRLRPPIMTMMRMAKTPQTVAGY 393 Query: 463 KVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSGPRSCIG 284 +P G + + R K+ W E +F P R+ +G+ A + F +G CIG Sbjct: 394 TIPPGHQVCVSPTVNQRLKDSWVERL-DFNPDRYLQDNPASGE-KFAYVPFGAGRHRCIG 451 Query: 283 QSFAMIEAKAVIAVILQRFSFSLSPKY 203 ++FA ++ K + + +L+ + F L Y Sbjct: 452 ENFAYVQIKTIWSTMLRLYEFDLIDGY 478
>CP19A_CANFA (Q5QQX7) Cytochrome P450 19A1 (EC 1.14.14.1) (Aromatase) (CYPXIX)| (Estrogen synthetase) (P-450AROM) Length = 503 Score = 68.2 bits (165), Expect = 2e-11 Identities = 45/144 (31%), Positives = 71/144 (49%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSDL 479 ++ HP+ +E + +E+ G D + KL +V F+ E++R V+L+ RKA D Sbjct: 322 IAKHPKVEESIMKEIQAVVGERDIRIDDMQKLKVVENFIYESMRYQPVVNLVMRKALQDD 381 Query: 478 EVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSGP 299 + G V +GT + + I +HR + + NEF F V P F GP Sbjct: 382 IIDGYLVKKGTNIILNIGRMHRLE--FFPKPNEFTLENFAKNVPYRYFQP-----FGFGP 434 Query: 298 RSCIGQSFAMIEAKAVIAVILQRF 227 RSC G+ AM+ K V+ +L+RF Sbjct: 435 RSCAGKYIAMVMMKVVLVTLLRRF 458
>CP19A_CALJA (Q95M61) Cytochrome P450 19A1 (EC 1.14.14.1) (Aromatase) (CYPXIX)| (Estrogen synthetase) (P-450AROM) Length = 503 Score = 68.2 bits (165), Expect = 2e-11 Identities = 44/144 (30%), Positives = 70/144 (48%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSDL 479 ++ HP +E + +E+ G D + KL +V F+ E++R V L+ RKA D Sbjct: 322 IAKHPNVEEAIMKEIQTVVGERDVKIDDIQKLKVVENFIYESMRYQPVVDLVMRKALEDD 381 Query: 478 EVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSGP 299 + G V +GT + + I +HR + + NEF F V P F GP Sbjct: 382 VIDGYPVKKGTNIILNIGRMHRLE--FFPKPNEFTLENFAKNVPYRYFQP-----FGFGP 434 Query: 298 RSCIGQSFAMIEAKAVIAVILQRF 227 RSC G+ AM+ K+++ +L+RF Sbjct: 435 RSCAGKYIAMVMMKSILVTLLRRF 458
>CP19A_ANGJA (Q6QHT9) Cytochrome P450 19A1 (EC 1.14.14.1) (Aromatase) (CYPXIX)| (Estrogen synthetase) (P-450AROM) Length = 511 Score = 67.8 bits (164), Expect = 3e-11 Identities = 42/145 (28%), Positives = 74/145 (51%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSDL 479 L +PE ++++ +E+ G + L L ++ F+ E+LR + V RK+ D Sbjct: 335 LKQNPEVEQEILKELDTVIGDKKAENSNLQHLIIMESFINESLRYHPVVDFTMRKSLEDD 394 Query: 478 EVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSGP 299 + G KV +GT + + + +H+ + + NEF FE V P F SGP Sbjct: 395 VIEGYKVFKGTNIILNVGRMHKCE--FFSKPNEFSLENFEKTVPNRFFQP-----FGSGP 447 Query: 298 RSCIGQSFAMIEAKAVIAVILQRFS 224 RSC+G+ +M+ KA++A +L R++ Sbjct: 448 RSCVGKHISMVMMKAILATLLSRYT 472
>C71AD_ARATH (O49342) Cytochrome P450 71A13 (EC 1.14.-.-)| Length = 497 Score = 67.8 bits (164), Expect = 3e-11 Identities = 48/147 (32%), Positives = 79/147 (53%), Gaps = 5/147 (3%) Frame = -1 Query: 646 PEWQEKLREEV---LRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLI-QRKAGSDL 479 P+ +KL++E+ +R GS + ++ N +L + E LRL+ + +I R D+ Sbjct: 318 PKSMKKLQDEIRSTIRPHGSYIKEKEVENMKYL-KAVIKEVLRLHPSLPMILPRLLSEDV 376 Query: 478 EVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMR-FENGVARAGKHPNALLSFSSG 302 +V G + GT + I I RD +WG DA EFKP R ++G+ GK+ N + F SG Sbjct: 377 KVKGYNIAAGTEVIINAWAIQRDTAIWGPDAEEFKPERHLDSGLDYHGKNLN-YIPFGSG 435 Query: 301 PRSCIGQSFAMIEAKAVIAVILQRFSF 221 R C G + A+ A+ +A ++ RF + Sbjct: 436 RRICPGINLALGLAEVTVANLVGRFDW 462
>C94A1_VICSA (O81117) Cytochrome P450 94A1 (EC 1.14.-.-) (P450-dependent fatty| acid omega-hydroxylase) Length = 514 Score = 67.8 bits (164), Expect = 3e-11 Identities = 43/144 (29%), Positives = 78/144 (54%), Gaps = 9/144 (6%) Frame = -1 Query: 631 KLREEVLRECG--SEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKA-GSDLEVGGIK 461 ++ EE++ E SE+ D + ++ + L E++RLY PV + ++A D+ G Sbjct: 336 RVEEEIVNELSKKSELMVYDEVKEMVYTHAALSESMRLYPPVPMDSKEAVNDDVLPDGWV 395 Query: 460 VPEGTVLTIPIATIHRDKEVWGEDANEFKPMRF-----ENGV-ARAGKHPNALLSFSSGP 299 V +GT++T + + R K +WG+D EF+P R+ NG G+ + F +GP Sbjct: 396 VKKGTIVTYHVYAMGRMKSLWGDDWAEFRPERWLEKDEVNGKWVFVGRDSYSYPVFQAGP 455 Query: 298 RSCIGQSFAMIEAKAVIAVILQRF 227 R C+G+ A ++ K ++A I+ +F Sbjct: 456 RVCLGKEMAFMQMKRIVAGIVGKF 479
>CP192_PIG (P79430) Cytochrome P450 19 type II (EC 1.14.14.1) (Aromatase)| (CYPXIXA2) (Estrogen synthetase) (P-450AROM) Length = 503 Score = 67.8 bits (164), Expect = 3e-11 Identities = 43/144 (29%), Positives = 70/144 (48%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSDL 479 ++ HP+ +E + +E+ G D + KL +V F+ E++R V L+ RKA D Sbjct: 322 IAKHPQVEEAIVKEIQTVIGERDIRNDDMQKLKVVENFIYESMRYQPVVDLVMRKALEDD 381 Query: 478 EVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSGP 299 + G V +GT + + I +HR + + NEF F V P F GP Sbjct: 382 VIDGYPVKKGTNIILNIGRMHRLE--FFPKPNEFTLENFAKNVPYRYFQP-----FGFGP 434 Query: 298 RSCIGQSFAMIEAKAVIAVILQRF 227 R+C G+ AM+ K + ++L+RF Sbjct: 435 RACAGKYIAMVMMKVTLVILLRRF 458
>C81D1_ARATH (Q9FG65) Cytochrome P450 81D1 (EC 1.14.-.-)| Length = 502 Score = 67.8 bits (164), Expect = 3e-11 Identities = 47/149 (31%), Positives = 71/149 (47%), Gaps = 3/149 (2%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSE--VPTGDMLNKLHLVNMFLLETLRLY-APVSLIQRKAG 488 L HP+ K R+E+ G + + D+ +L N+ +LETLRL+ A L+ A Sbjct: 322 LLNHPDVISKARDEIDNRVGLDRLIEEADLSELPYLKNI-VLETLRLHPATPLLVPHMAS 380 Query: 487 SDLEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFS 308 D ++G +P GT L + IHRD W +D + FKP RFE + LL+F Sbjct: 381 EDCKIGSYDMPRGTTLLVNAWAIHRDPNTW-DDPDSFKPERFEK-----EEEAQKLLAFG 434 Query: 307 SGPRSCIGQSFAMIEAKAVIAVILQRFSF 221 G R+C G A + ++Q F + Sbjct: 435 LGRRACPGSGLAQRIVGLALGSLIQCFEW 463
>CP19A_RABIT (Q29605) Cytochrome P450 19A1 (EC 1.14.14.1) (Aromatase) (CYPXIX)| (Estrogen synthetase) (P-450AROM) Length = 503 Score = 67.4 bits (163), Expect = 4e-11 Identities = 44/144 (30%), Positives = 68/144 (47%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSDL 479 ++ HP +E + EE+ G D + KL +V F+ E++R V L+ RKA D Sbjct: 322 IAKHPSVEEAIMEEIQTVVGERDIRIDDIQKLKVVENFIYESMRYQPVVDLVMRKALEDD 381 Query: 478 EVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSGP 299 + G V +GT + + I +HR + + NEF F V P F GP Sbjct: 382 VIDGYPVKKGTNIILNIGRMHRLE--FFPKPNEFTLENFAKNVPYRYFQP-----FGFGP 434 Query: 298 RSCIGQSFAMIEAKAVIAVILQRF 227 R C G+ AM+ K ++ +L+RF Sbjct: 435 RGCAGKYIAMVMMKVILVTLLRRF 458
>CP19A_HORSE (O46512) Cytochrome P450 19A1 (EC 1.14.14.1) (Aromatase) (CYPXIX)| (Estrogen synthetase) (P-450AROM) (P450 17-alpha) Length = 503 Score = 67.4 bits (163), Expect = 4e-11 Identities = 44/144 (30%), Positives = 70/144 (48%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSDL 479 ++ HP+ +E L +E+ G D + KL ++ F+ E++R V ++ RKA D Sbjct: 322 IAQHPKVEEALMKEIQTVLGERDLKNDDMQKLKVMENFINESMRYQPVVDIVMRKALEDD 381 Query: 478 EVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSGP 299 + G V +GT + + I +H K + NEF FE V P F GP Sbjct: 382 VIDGYPVKKGTNIILNIGRMH--KLEFFPKPNEFTLENFEKNVPYRYFQP-----FGFGP 434 Query: 298 RSCIGQSFAMIEAKAVIAVILQRF 227 RSC G+ AM+ K ++ +L+RF Sbjct: 435 RSCAGKFIAMVMMKVMLVSLLRRF 458
>CP6G2_DROME (Q9V675) Probable cytochrome P450 6g2 (EC 1.14.-.-) (CYPVIG2)| Length = 519 Score = 67.4 bits (163), Expect = 4e-11 Identities = 51/165 (30%), Positives = 81/165 (49%), Gaps = 11/165 (6%) Frame = -1 Query: 658 LSTHPEWQEKLREEV---LRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRK-- 494 L+ + Q++LREE+ L E G +V T M+ L + M LLE LR+Y P+ + R+ Sbjct: 332 LAKDTDVQQRLREEIKDALVESGGQV-TLKMIESLEFMQMILLEVLRMYPPLPFLDRECT 390 Query: 493 AGSDLEVGGIK----VPEGTVLTIPIATIHRDKEVWGEDANEFKPMRF--ENGVARAGKH 332 +G D + VP+G + IP +H D + + + +F P RF EN R Sbjct: 391 SGRDYSLAPFHKKFVVPKGMPVYIPCYALHMDPQYFPQP-RKFLPERFSPEN---RKLHT 446 Query: 331 PNALLSFSSGPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVH 197 P + F GP CIG+ F ++AK + +L+ + S + H Sbjct: 447 PYTYMPFGLGPHGCIGERFGYLQAKVGLVNLLRNHMITTSERTPH 491
>CP67_UROFA (O00061) Cytochrome P450 67 (EC 1.14.-.-) (CYPLXVII)| (Planta-induced rust protein 16) (Fragment) Length = 541 Score = 67.4 bits (163), Expect = 4e-11 Identities = 47/163 (28%), Positives = 77/163 (47%), Gaps = 11/163 (6%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTGDMLNKLHLVNMFLLETLRLY--APVSLIQRKAGS 485 L HP + E+L+ E+L P+ L++L +N L ET+RL +P +L + Sbjct: 350 LLKHPNYMEQLQAELLAAPDLSPPS---LSRLEYLNACLQETMRLQPPSPANLQRICPPG 406 Query: 484 DLEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRF---------ENGVARAGKH 332 + G ++PEGT + IHRD+ + A EF+P R+ G + Sbjct: 407 GAVICGRQIPEGTKVRFSNYAIHRDERYFSR-AEEFRPQRWLQKAKDDLGNQGEEKERLD 465 Query: 331 PNALLSFSSGPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKY 203 A F GP +C+ ++ A +E + V+A IL F S +P + Sbjct: 466 QRAFFGFLIGPGACVAKNLAWMEMRLVVATILTNFDLSFAPGF 508
>C71BZ_ARATH (Q9LXM3) Cytochrome P450 71B38 (EC 1.14.-.-)| Length = 500 Score = 67.4 bits (163), Expect = 4e-11 Identities = 48/152 (31%), Positives = 79/152 (51%), Gaps = 4/152 (2%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECG--SEVPTGDMLNKLHLVNMFLLETLRLYAPVS-LIQRKAG 488 LS HP +KL+EE+ G E T + L K+ + + ++ET RL+ P L+ R Sbjct: 317 LSRHPRVMKKLQEEIRAMLGPNKERITEEDLEKVEYLKLVMVETFRLHPPAPLLLPRLTM 376 Query: 487 SDLEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRF-ENGVARAGKHPNALLSF 311 SD+++ G +P+ T++ I I RD + W + EF P RF ++ + G+H LL F Sbjct: 377 SDIKIQGYNIPKNTMIQINTYAIGRDPKYW-KQPGEFIPERFLDSPIDYKGQH-FELLPF 434 Query: 310 SSGPRSCIGQSFAMIEAKAVIAVILQRFSFSL 215 +G R C G + + + + +L F +SL Sbjct: 435 GAGRRICPGMATGITMVELGLLNLLYFFDWSL 466
>C76B1_HELTU (O23976) Cytochrome P450 76B1 (EC 1.14.-.-) (7-ethoxycoumarin| O-deethylase) (ECOD) (Phenylurea dealkylase) Length = 490 Score = 67.4 bits (163), Expect = 4e-11 Identities = 51/166 (30%), Positives = 79/166 (47%), Gaps = 3/166 (1%) Frame = -1 Query: 646 PEWQEKLREEVLRECG--SEVPTGDMLNKLHLVNMFLLETLRLYAPVSLI-QRKAGSDLE 476 P K +EE+ + G S V D+L +L ++ + E LRL+ P L+ RK + +E Sbjct: 313 PHIMSKAKEELEKVIGKGSIVKEDDVL-RLPYLSCIVKEVLRLHPPSPLLLPRKVVTQVE 371 Query: 475 VGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSGPR 296 + G +P GT++ + I RD VW +D+ EFKP RF H L+ F +G R Sbjct: 372 LSGYTIPAGTLVFVNAWAIGRDPTVW-DDSLEFKPQRFLESRLDVRGHDFDLIPFGAGRR 430 Query: 295 SCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVHAPMDVITLRPKFG 158 C G A ++ +L F + + K P DV+ + K G Sbjct: 431 ICPGIPLATRMVPIMLGSLLNNFDWKIDTK---VPYDVLDMTEKNG 473
>CP51A_HUMAN (Q16850) Cytochrome P450 51A1 (EC 1.14.13.70) (CYPLI) (P450LI)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (LDM) (P450-14DM) (P45014DM) Length = 503 Score = 67.0 bits (162), Expect = 5e-11 Identities = 44/147 (29%), Positives = 73/147 (49%), Gaps = 2/147 (1%) Frame = -1 Query: 637 QEKLREEVLRECGSEVP--TGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSDLEVGGI 464 Q+K E CG +P T D L L+L++ + ETLRL P+ ++ R A + V G Sbjct: 334 QKKCYLEQKTVCGENLPPLTYDQLKDLNLLDRCIKETLRLRPPIMIMMRMARTPQTVAGY 393 Query: 463 KVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSGPRSCIG 284 +P G + + R K+ W E +F P R+ +G+ A + F +G CIG Sbjct: 394 TIPPGHQVCVSPTVNQRLKDSWVERL-DFNPDRYLQDNPASGE-KFAYVPFGAGRHRCIG 451 Query: 283 QSFAMIEAKAVIAVILQRFSFSLSPKY 203 ++FA ++ K + + +L+ + F L Y Sbjct: 452 ENFAYVQIKTIWSTMLRLYEFDLIDGY 478
>CP19A_CHICK (P19098) Cytochrome P450 19A1 (EC 1.14.14.1) (Aromatase) (CYPXIX)| (Estrogen synthetase) (P-450AROM) Length = 507 Score = 67.0 bits (162), Expect = 5e-11 Identities = 44/143 (30%), Positives = 67/143 (46%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSDL 479 ++ P +EK+ E+ G D + L +V F+ E++R V LI RKA D Sbjct: 321 IADDPTVEEKMMREIETVMGDREVQSDDMPNLKIVENFIYESMRYQPVVDLIMRKALQDD 380 Query: 478 EVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSGP 299 + G V +GT + + I +H K + NEF FE V P F GP Sbjct: 381 VIDGYPVKKGTNIILNIGRMH--KLEFFPKPNEFSLENFEKNVPSRYFQP-----FGFGP 433 Query: 298 RSCIGQSFAMIEAKAVIAVILQR 230 R C+G+ AM+ KA++ +L+R Sbjct: 434 RGCVGKFIAMVMMKAILVTLLRR 456
>C71AE_ARATH (P58045) Cytochrome P450 71A14 (EC 1.14.-.-)| Length = 497 Score = 67.0 bits (162), Expect = 5e-11 Identities = 42/155 (27%), Positives = 76/155 (49%), Gaps = 3/155 (1%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVP--TGDMLNKLHLVNMFLLETLRLYAPVSL-IQRKAG 488 L HPE +KL++E+ + + + + + + + + E LRL+ P+ L + R+ Sbjct: 315 LIRHPECMKKLQDEIRAKATKLILYISEEDVEDMKYLKAVVKEVLRLHPPLPLLVPRELS 374 Query: 487 SDLEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFS 308 D+++ G + GT + I I RD WG DA EF+P R + + + F Sbjct: 375 EDIKLKGYDIAAGTQVIINAWAIQRDTMTWGIDAEEFRPERHLDSLVDFRGTNFEFIPFG 434 Query: 307 SGPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKY 203 SG R C G FAM + +A ++ RF++ + ++ Sbjct: 435 SGRRICPGIGFAMALVEVTLANLVNRFNWRMEVQH 469
>CP2D4_RAT (P13108) Cytochrome P450 2D4 (EC 1.14.14.1) (CYPIID4) (P450-DB4)| (P450-CMF3) (Debrisoquine 4-hydroxylase) Length = 500 Score = 67.0 bits (162), Expect = 5e-11 Identities = 45/148 (30%), Positives = 77/148 (52%), Gaps = 3/148 (2%) Frame = -1 Query: 649 HPEWQEKLREEVLRECGSEVPTGDMLNKLHL--VNMFLLETLRLYAPVSL-IQRKAGSDL 479 HP+ Q ++++E+ G +V +M ++ + N + E R + L + K D+ Sbjct: 327 HPDVQCRVQQEIDEVIG-QVRRPEMADQARMPFTNAVIHEVQRFADILPLGVPHKTSRDI 385 Query: 478 EVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSGP 299 EV G +P+GT L ++++ +D+ VW E F P F + KH A + FS+G Sbjct: 386 EVQGFLIPKGTTLITNLSSVLKDETVW-EKPLRFHPEHFLDAQGNFVKH-EAFMPFSAGR 443 Query: 298 RSCIGQSFAMIEAKAVIAVILQRFSFSL 215 R+C+G+ A +E +LQRFSFS+ Sbjct: 444 RACLGEPLARMELFLFFTCLLQRFSFSV 471
>CP6B7_HELAM (O61387) Cytochrome P450 6B7 (EC 1.14.14.1) (CYPVIB7)| Length = 504 Score = 67.0 bits (162), Expect = 5e-11 Identities = 54/177 (30%), Positives = 89/177 (50%), Gaps = 9/177 (5%) Frame = -1 Query: 658 LSTHPEWQEKLREEV---LRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAG 488 LS + + Q KL EV ++ +V T D + ++ +N ETLR+Y+ V +QRKA Sbjct: 321 LSLNQDVQNKLIAEVDEAIKASDGKV-TYDTVKEMKYLNKVFDETLRMYSIVEPLQRKAT 379 Query: 487 SDLEVGG--IKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGK-HPNALL 317 D ++ G + + + T++ I IH D + + ++ +F P RF+ GK HP A L Sbjct: 380 RDYQIPGTDVVIEKDTMVLISPRGIHYDPKYY-DNPKQFNPDRFD--AEEVGKRHPCAYL 436 Query: 316 SFSSGPRSCIGQSFAMIEAKAVIAVILQRFSFSLS---PKYVHAPMDVITLRPKFGL 155 F G R+CIG F +++ I IL +F S + + +T+ PK G+ Sbjct: 437 PFGLGQRNCIGMRFGRLQSLLCITKILSKFRIEPSKNTDRNLQVEPRRVTIGPKGGI 493
>CP2DA_RAT (P12939) Cytochrome P450 2D10 (EC 1.14.14.1) (CYPIID10) (P450-DB5)| (P450-CMF1B) (Debrisoquine 4-hydroxylase) Length = 504 Score = 66.6 bits (161), Expect = 6e-11 Identities = 46/149 (30%), Positives = 79/149 (53%), Gaps = 4/149 (2%) Frame = -1 Query: 649 HPEWQEKLREEVLRECGSEVPTGDMLNKLHL--VNMFLLETLRL--YAPVSLIQRKAGSD 482 +P+ Q ++++E+ G +V +M ++ H+ N + E R AP++L R D Sbjct: 327 YPDVQRRVQQEIDEVIG-QVRCPEMTDQAHMPYTNAVIHEVQRFGDIAPLNL-PRITSCD 384 Query: 481 LEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSG 302 +EV +P+GT L I ++++ +D+ VW E F P F + KH A + FS+G Sbjct: 385 IEVQDFVIPKGTTLIINLSSVLKDETVW-EKPLRFHPEHFLDAQGNFVKH-EAFMPFSAG 442 Query: 301 PRSCIGQSFAMIEAKAVIAVILQRFSFSL 215 R+C+G+ A +E +LQ FSFS+ Sbjct: 443 RRACLGEPLARMELFLFFTCLLQHFSFSV 471
>CP17A_PERLE (Q91Z85) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 509 Score = 66.6 bits (161), Expect = 6e-11 Identities = 50/166 (30%), Positives = 85/166 (51%), Gaps = 4/166 (2%) Frame = -1 Query: 649 HPEWQEKLREEVLRECG-SEVPTGDMLNKLHLVNMFLLETLRLYAPVS--LIQRKAGSDL 479 +PE ++K+++E+ + G S PT + N L ++ + E LR+ PV+ LI KA D Sbjct: 319 NPEVKKKIQKEIDQNIGFSRTPTFNDRNHLLMLEATIREVLRI-RPVAPMLIPHKANIDS 377 Query: 478 EVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPN-ALLSFSSG 302 +G +P+ T + I + +H +++ W + + F P RF + P+ + L F +G Sbjct: 378 SIGEFTIPKDTHVVINLWALHHNEKEW-DQPDRFMPERFLDATGSHLITPSLSYLPFGAG 436 Query: 301 PRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVHAPMDVITLRPK 164 PR+CIG+ A +A +LQRF + APM + PK Sbjct: 437 PRACIGEVLARQVLFLYVACLLQRFDLDVPD---GAPMPCLKGDPK 479
>C19AA_BRARE (O42145) Cytochrome P450 19A1a (EC 1.14.14.1) (Aromatase) (CYPXIX)| (Estrogen synthetase) (P-450AROM) Length = 509 Score = 66.6 bits (161), Expect = 6e-11 Identities = 41/145 (28%), Positives = 71/145 (48%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSDL 479 L +P+ + K+ +E+ + L+KL ++ F+ E+LR + V R+A D Sbjct: 341 LKQNPDVELKILQEMDSVLAGQSLQHSHLSKLQILESFINESLRFHPVVDFTMRRALDDD 400 Query: 478 EVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSGP 299 + G V +GT + + + +HR + + N+F F V P F SGP Sbjct: 401 VIEGYNVKKGTNIILNVGRMHRSE--FFSKPNQFSLDNFHKNVPSRFFQP-----FGSGP 453 Query: 298 RSCIGQSFAMIEAKAVIAVILQRFS 224 RSC+G+ AM+ K+++ +L RFS Sbjct: 454 RSCVGKHIAMVMMKSILVALLSRFS 478
>CP17A_HORSE (Q95328) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 66.6 bits (161), Expect = 6e-11 Identities = 49/148 (33%), Positives = 79/148 (53%), Gaps = 4/148 (2%) Frame = -1 Query: 646 PEWQEKLREEVLRECG-SEVPTGDMLNKLHLVNMFLLETLRLYAPVS--LIQRKAGSDLE 476 P+ ++K++EE+ + G S PT N+L L+ + E LR+ PV+ LI KA D Sbjct: 322 PQLKKKIQEEIDQNVGFSRTPTLSDRNRLLLLEATIREVLRI-RPVAPMLIPHKALVDSS 380 Query: 475 VGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPN-ALLSFSSGP 299 +G V +GT + I + +H +++ W + + F P RF + P+ + L F +GP Sbjct: 381 IGEFAVDDGTNVIINLWALHHNEKEWHQP-DRFMPERFLDPTGSQLISPSLSYLPFGAGP 439 Query: 298 RSCIGQSFAMIEAKAVIAVILQRFSFSL 215 RSCIG+ A E A +LQRF+ + Sbjct: 440 RSCIGELLARQELFLFTAWLLQRFNLEV 467
>C98A2_SOYBN (O48922) Cytochrome P450 98A2 (EC 1.14.-.-)| Length = 509 Score = 66.2 bits (160), Expect = 8e-11 Identities = 48/150 (32%), Positives = 79/150 (52%), Gaps = 3/150 (2%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSE-VPTGDMLNKLHLVNMFLLETLRLYAPVSL-IQRKAGS 485 L +P Q+K++EE+ R G E V T + L + E +RL+ P L + +A + Sbjct: 316 LIRNPRVQQKVQEELDRVIGLERVMTEADFSNLPYLQCVTKEAMRLHPPTPLMLPHRANA 375 Query: 484 DLEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRF-ENGVARAGKHPNALLSFS 308 +++VGG +P+G+ + + + + RD VW +D EF+P RF E V G H LL F Sbjct: 376 NVKVGGYDIPKGSNVHVNVWAVARDPAVW-KDPLEFRPERFLEEDVDMKG-HDFRLLPFG 433 Query: 307 SGPRSCIGQSFAMIEAKAVIAVILQRFSFS 218 SG R C G + A +++ +L F ++ Sbjct: 434 SGRRVCPGAQLGINLAASMLGHLLHHFCWT 463
>CP21A_CANFA (Q8WNW0) Cytochrome P450 21 (EC 1.14.99.10) (Cytochrome P450 XXI)| (Steroid 21-hydroxylase) (21-OHase) (P450-C21) (P-450c21) Length = 492 Score = 66.2 bits (160), Expect = 8e-11 Identities = 56/168 (33%), Positives = 84/168 (50%), Gaps = 6/168 (3%) Frame = -1 Query: 649 HPEWQEKLREEVLRECG-----SEVPTGDMLNKLHLVNMFLLETLRLYAPVSL-IQRKAG 488 HPE Q++L+EE+ RE G S +P D +L L++ + E LRL V L + Sbjct: 308 HPEIQQRLQEELDRELGPGASGSRIPYRDP-TRLPLLSATVAEVLRLRPVVPLALPHCTT 366 Query: 487 SDLEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFS 308 + G +PEG V+ + H D+ VW E EF+P RF G P +L+F Sbjct: 367 RPSSISGYDIPEGMVVIPNLQGAHLDETVW-ERPQEFRPDRF----LVPGASPR-VLAFG 420 Query: 307 SGPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVHAPMDVITLRPK 164 G R C+G+ A +E V+A +L+ +F+L P P +LRP+ Sbjct: 421 CGARVCLGEPLARLELLVVLAQLLR--AFTLMPAAGTLP----SLRPR 462
>C71AL_ARATH (Q9STL2) Cytochrome P450 71A21 (EC 1.14.-.-)| Length = 490 Score = 66.2 bits (160), Expect = 8e-11 Identities = 42/150 (28%), Positives = 71/150 (47%), Gaps = 2/150 (1%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTGDM-LNKLHLVNMFLLETLRLYAPVSLIQ-RKAGS 485 L HPE L+EEV C + + + + + + ET RL+ P+ L+ ++ Sbjct: 308 LLRHPECLRTLQEEVRTICKGNLSVSEEDIQNMSYLKAVIKETTRLHPPLPLLAPHESIQ 367 Query: 484 DLEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSS 305 D+ +G +P GT + I I R+ WG DA +F+P R + H L+ F + Sbjct: 368 DVILGDYHIPAGTQVMINAWAIGREAATWGPDAEKFRPERHLDSSVDFRGHNFELVPFGA 427 Query: 304 GPRSCIGQSFAMIEAKAVIAVILQRFSFSL 215 G R C SFA++ + +A + R+ + L Sbjct: 428 GRRICPAISFAVVLIEVALANFVHRYDWKL 457
>CP2DI_RAT (Q64680) Cytochrome P450 2D18 (EC 1.14.14.1) (CYPIID18) (P450| 2D-29/2D-35) Length = 500 Score = 65.9 bits (159), Expect = 1e-10 Identities = 45/147 (30%), Positives = 77/147 (52%), Gaps = 3/147 (2%) Frame = -1 Query: 646 PEWQEKLREEVLRECGSEVPTGDMLNKLHL--VNMFLLETLRLYAPVSL-IQRKAGSDLE 476 P+ Q ++++E+ G +V +M ++ + N + E R + L + K D+E Sbjct: 328 PDVQCRVQQEIDEVIG-QVRRPEMADQARMPFTNAVIHEVQRFADILPLGVPHKTSRDIE 386 Query: 475 VGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSGPR 296 V G +P+GT L I ++++ +D+ VW E F P F + KH A + FS+G R Sbjct: 387 VQGFLIPKGTTLIINLSSVLKDETVW-EKPLRFHPEHFLDAQGNFVKH-EAFMPFSAGRR 444 Query: 295 SCIGQSFAMIEAKAVIAVILQRFSFSL 215 +C+G+ A +E +LQRFSFS+ Sbjct: 445 ACLGEPLARMELFLFFTCLLQRFSFSV 471
>C71AC_ARATH (O49340) Cytochrome P450 71A12 (EC 1.14.-.-)| Length = 497 Score = 65.9 bits (159), Expect = 1e-10 Identities = 48/151 (31%), Positives = 77/151 (50%), Gaps = 5/151 (3%) Frame = -1 Query: 658 LSTHPEWQEKLREEV---LRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLI-QRKA 491 L +P +KL++E+ +R GS + D+ N +L + E R++ P+ LI R Sbjct: 314 LIRNPNVMKKLQDEIRSTIRPHGSYIKEKDVENMKYL-KAVIKEVFRVHPPLPLILPRLL 372 Query: 490 GSDLEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMR-FENGVARAGKHPNALLS 314 D++V G + GT + I I RD +WG DA EFKP R ++ + GK N + Sbjct: 373 SEDVKVKGYNIAAGTEVIINAWAIQRDPAIWGPDAEEFKPERHLDSTLDYHGKDLN-FIP 431 Query: 313 FSSGPRSCIGQSFAMIEAKAVIAVILQRFSF 221 F SG R C G + A+ + +A ++ RF + Sbjct: 432 FGSGRRICPGINLALGLVEVTVANLVGRFDW 462
>CP17A_MESAU (P70687) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 511 Score = 65.9 bits (159), Expect = 1e-10 Identities = 46/149 (30%), Positives = 80/149 (53%), Gaps = 4/149 (2%) Frame = -1 Query: 649 HPEWQEKLREEVLRECG-SEVPTGDMLNKLHLVNMFLLETLRLYAPVS--LIQRKAGSDL 479 +PE ++K+++E+ + G S PT + N L ++ + E LR+ PV+ LI +A SD+ Sbjct: 321 NPEVKKKIQKEIDQNIGFSRTPTFNDRNHLLMLEATIREVLRI-RPVAPMLIPHRANSDM 379 Query: 478 EVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPN-ALLSFSSG 302 +G +P+ T + I + +H ++ W + + F P RF + P+ + L F +G Sbjct: 380 SIGEFSIPKFTPVIINLWALHHSEKEW-DQPDRFMPERFLDPTGSHLITPSLSYLPFGAG 438 Query: 301 PRSCIGQSFAMIEAKAVIAVILQRFSFSL 215 RSCIG+ A E +A +LQRF + Sbjct: 439 ARSCIGEVLARQELFLFMAHLLQRFDLDV 467
>CP301_DROME (Q9V6D6) Probable cytochrome P450 301a1, mitochondrial precursor| (EC 1.14.-.-) (CYPCCCIA1) Length = 553 Score = 65.9 bits (159), Expect = 1e-10 Identities = 48/163 (29%), Positives = 82/163 (50%), Gaps = 5/163 (3%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGS-EVP-TGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGS 485 L+T P Q+K+ EE+ R P T +L+++H + F+ E R+Y+ V R Sbjct: 376 LATRPVDQQKVHEELKRLLPDPNTPLTIPLLDQMHHLKGFIKEVFRMYSTVIGNGRTLME 435 Query: 484 DLEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRF---ENGVARAGKHPNALLS 314 D + G +VP+G P + + E + DA F+P R+ ++G HP A L Sbjct: 436 DSVICGYQVPKGVQAVFP-TIVTGNMEEYVTDAATFRPERWLKPQHGGTPGKLHPFASLP 494 Query: 313 FSSGPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVHAPMD 185 + G R C+G+ FA +E + ++A +L+ + +Y H P+D Sbjct: 495 YGYGARMCLGRRFADLEMQILLAKLLRNYKL----EYNHKPLD 533
>CP317_DROME (Q9V776) Probable cytochrome P450 317a1 (EC 1.14.-.-)| (CYPCCCXVIIA1) Length = 518 Score = 65.9 bits (159), Expect = 1e-10 Identities = 50/157 (31%), Positives = 78/157 (49%), Gaps = 6/157 (3%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLR--ECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGS 485 L+ HPE Q ++REEV + E T + + L + + ETLR++ I R+ + Sbjct: 336 LALHPELQVRVREEVKKAIERHDGHITHEGIKSLSFMGQVINETLRMHPITPYILRRTLN 395 Query: 484 DLEVGG----IKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALL 317 D V I V E L IP IH D +++ D EFKP R+ +G + + Sbjct: 396 DYAVPDHPKYILVKE-LFLIIPTHAIHHDPDIY-PDPEEFKPDRW-SGPRDSLQEQGTWF 452 Query: 316 SFSSGPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPK 206 F G RSCIG FA ++ + +A++L + FSL+ + Sbjct: 453 GFGVGARSCIGIQFAQLQLRLALALLLSEYEFSLNTR 489
>CP318_DROME (Q9VYQ5) Probable cytochrome P450 318a1 (EC 1.14.-.-)| (CYPCCCXVIIIA1) Length = 536 Score = 65.9 bits (159), Expect = 1e-10 Identities = 44/174 (25%), Positives = 79/174 (45%), Gaps = 35/174 (20%) Frame = -1 Query: 580 DMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSDLEVGGIK----VPEGTVLTIPIATIHR 413 + L +L ++ F+ E+LRL A V + R D + G + VP+ +++ + + R Sbjct: 359 EQLQQLRYLDAFVSESLRLLATVPMNLRHVSRDFRLAGRQHETIVPQNSIVVLDTFNMQR 418 Query: 412 DKEVWGEDANEFKPMRF------------------ENGVARAGKHPNALLSFSSGPRSCI 287 D+ WG +A +F P RF E R +H + L FS+G RSCI Sbjct: 419 DERWWGANARQFDPQRFLDQEEEQLSKGHNDSGSGEKRRQRDRRHSYSFLPFSNGLRSCI 478 Query: 286 GQSFAMIEAKAVIAVILQRFSF-------------SLSPKYVHAPMDVITLRPK 164 G+ + + K + ++ F F ++S K+ +A ++T++PK Sbjct: 479 GRRYGLFIMKVFLVKLITNFDFQSDFELEKLQFVENISLKFKNADDILLTIQPK 532
>CP6B2_HELAM (Q27664) Cytochrome P450 6B2 (EC 1.14.14.1) (CYPVIB2)| Length = 504 Score = 65.5 bits (158), Expect = 1e-10 Identities = 49/150 (32%), Positives = 79/150 (52%), Gaps = 6/150 (4%) Frame = -1 Query: 658 LSTHPEWQEKLREEV---LRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAG 488 L+ +P+ Q KL E+ ++ G +V T D + + +N ETLR+Y+ V +QRKA Sbjct: 321 LALNPDIQNKLIAEIDEAIKANGGKV-TYDTVKDMKYLNKVFDETLRMYSIVEPLQRKAI 379 Query: 487 SDLEVGG--IKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGK-HPNALL 317 D ++ G + + + TV+ I IH D + + ++ +F P RF GK HP A L Sbjct: 380 RDYKLPGTDVVIEKDTVVLISPRGIHYDPKYY-DNPKQFNPERFF--AEEVGKRHPCAYL 436 Query: 316 SFSSGPRSCIGQSFAMIEAKAVIAVILQRF 227 F G R+CIG F +++ I +L +F Sbjct: 437 PFGLGQRNCIGMRFGRLQSLLCITKLLSKF 466
>CP2D6_HUMAN (P10635) Cytochrome P450 2D6 (EC 1.14.14.1) (CYPIID6) (P450-DB1)| (Debrisoquine 4-hydroxylase) Length = 497 Score = 65.5 bits (158), Expect = 1e-10 Identities = 45/148 (30%), Positives = 76/148 (51%), Gaps = 3/148 (2%) Frame = -1 Query: 649 HPEWQEKLREEVLRECGSEVPTGDMLNKLHL--VNMFLLETLRLYAPVSL-IQRKAGSDL 479 HP+ Q ++++E+ G +V +M ++ H+ + E R V L + D+ Sbjct: 324 HPDVQRRVQQEIDDVIG-QVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDI 382 Query: 478 EVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSGP 299 EV G ++P+GT L ++++ +D+ VW E F P F + K P A L FS+G Sbjct: 383 EVQGFRIPKGTTLITNLSSVLKDEAVW-EKPFRFHPEHFLDAQGHFVK-PEAFLPFSAGR 440 Query: 298 RSCIGQSFAMIEAKAVIAVILQRFSFSL 215 R+C+G+ A +E +LQ FSFS+ Sbjct: 441 RACLGEPLARMELFLFFTSLLQHFSFSV 468
>CP17A_CAVPO (Q64410) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 65.5 bits (158), Expect = 1e-10 Identities = 43/149 (28%), Positives = 80/149 (53%), Gaps = 4/149 (2%) Frame = -1 Query: 649 HPEWQEKLREEVLRECG-SEVPTGDMLNKLHLVNMFLLETLRL--YAPVSLIQRKAGSDL 479 +P+ ++K++EE+ G S PT N L ++ + E LR+ AP+ LI KA +D Sbjct: 321 NPQVKKKIQEEIDHNVGFSRTPTFSDRNHLLMLEATIREVLRIRPVAPI-LIPHKANTDS 379 Query: 478 EVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNA-LLSFSSG 302 +G + + T + + + +H +++ W + ++F P RF + P++ L F +G Sbjct: 380 SIGEFAIDKDTNVLVNLWALHHNEQEW-DRPDQFMPERFLDPTGSQIIVPSSSYLPFGAG 438 Query: 301 PRSCIGQSFAMIEAKAVIAVILQRFSFSL 215 PRSC+G++ A E + A +LQ+F + Sbjct: 439 PRSCVGEALARQEIFLITAWLLQKFDLEV 467
>CP19A_HUMAN (P11511) Cytochrome P450 19A1 (EC 1.14.14.1) (Aromatase) (CYPXIX)| (Estrogen synthetase) (P-450AROM) Length = 502 Score = 65.5 bits (158), Expect = 1e-10 Identities = 43/144 (29%), Positives = 69/144 (47%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAGSDL 479 ++ HP +E + +E+ G D + KL ++ F+ E++R V L+ RKA D Sbjct: 321 IAKHPNVEEAIIKEIQTVIGERDIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDD 380 Query: 478 EVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLSFSSGP 299 + G V +GT + + I +HR + + NEF F V P F GP Sbjct: 381 VIDGYPVKKGTNIILNIGRMHRLE--FFPKPNEFTLENFAKNVPYRYFQP-----FGFGP 433 Query: 298 RSCIGQSFAMIEAKAVIAVILQRF 227 R C G+ AM+ KA++ +L+RF Sbjct: 434 RGCAGKYIAMVMMKAILVTLLRRF 457
>C6A23_DROME (Q9V771) Probable cytochrome P450 6a23 (EC 1.14.-.-) (CYPVIA23)| Length = 502 Score = 65.5 bits (158), Expect = 1e-10 Identities = 55/181 (30%), Positives = 92/181 (50%), Gaps = 5/181 (2%) Frame = -1 Query: 658 LSTHPEWQEKLREE---VLRECGSEVPTGDMLNKLHLVNMFLLETLRLYAPVSLIQRKAG 488 L+ + Q++LR E VL + +E T + + ++ + ++ETLR Y ++ + R Sbjct: 321 LALDQDIQDQLRAEINNVLSKHNNEF-TYEGIKEMKYLEQVVMETLRKYPVLAHLTRMTQ 379 Query: 487 SDLEVGGIK--VPEGTVLTIPIATIHRDKEVWGEDANEFKPMRFENGVARAGKHPNALLS 314 +D K + +GT + IP IH D E++ E +FKP RF + A A + L Sbjct: 380 TDFSPEDPKYFIAKGTTVVIPALGIHYDPEIYPEP-EKFKPERFTDE-AIAARPSCTWLP 437 Query: 313 FSSGPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVHAPMDVITLRPKFGLPMILKSI 134 F GPR+CIG F +++A +A +++ + FS+S + PM KF + IL S Sbjct: 438 FGEGPRNCIGLRFGLMQACVGLAYLIRGYKFSVSTE-TQIPM-------KFVVKSILLSA 489 Query: 133 E 131 E Sbjct: 490 E 490
>CP26B_BRARE (Q6EIG3) Cytochrome P450 26B1 (EC 1.14.-.-) (Cyp26B1)| (Retinoic-acid metabolizing cytochrome) Length = 511 Score = 65.1 bits (157), Expect = 2e-10 Identities = 60/196 (30%), Positives = 87/196 (44%), Gaps = 11/196 (5%) Frame = -1 Query: 658 LSTHPEWQEKLREEVLRECG---------SEVPTGDMLNKLHLVNMFLLETLRLYAPVSL 506 L HP EKLREE LR CG E+ D + L ++ + E LRL+APVS Sbjct: 312 LLRHPAVLEKLREE-LRSCGLLHDGCLCQGELRL-DSIISLKYLDCVIKEVLRLFAPVSG 369 Query: 505 IQRKAGSDLEVGGIKVPEGTVLTIPIATIHRDKEVWGEDANEFKPMRF--ENGVARAGKH 332 R A E+ G++VP+G + I H V+ +D F P RF E R G+ Sbjct: 370 GYRIATQTFELDGVQVPKGWSVMYSIRDTHDTSAVF-KDVEAFDPDRFSPERSEDREGRF 428 Query: 331 PNALLSFSSGPRSCIGQSFAMIEAKAVIAVILQRFSFSLSPKYVHAPMDVITLRPKFGLP 152 L F G RSC+G+ A + K + + F LS + + V + P GL Sbjct: 429 --HYLPFGGGVRSCLGKQLATLFLKLLAVELAGGSRFELSTRTFPRMISVPVVHPTDGLR 486 Query: 151 MILKSIEI*KNVYVVK 104 + ++ +N + K Sbjct: 487 VKFFGLDSNQNQIMAK 502 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 95,549,841 Number of Sequences: 219361 Number of extensions: 2121448 Number of successful extensions: 6115 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 5486 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5644 length of database: 80,573,946 effective HSP length: 108 effective length of database: 56,882,958 effective search space used: 6257125380 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
