>SYP_CLOST (Q9L4Q8) Prolyl-tRNA synthetase (EC 6.1.1.15) (Proline--tRNA|
           ligase) (ProRS)
          Length = 481

 Score = 95.9 bits (237), Expect = 9e-20
 Identities = 51/145 (35%), Positives = 75/145 (51%), Gaps = 1/145 (0%)
 Frame = -1

Query: 634 EMKGVPIRIELGPRDVKNRSVVLSRRDVPGKQGKEFGISMEPSILVDHIKGRLEEIQASL 455
           EMKGVP+R+E+GPRD++N   +++RRD   K       S     + D +K  L+ +   +
Sbjct: 343 EMKGVPLRLEIGPRDIENNVAMIARRDTLSKD------SYSLDNIGDTVKNLLDTVHTDM 396

Query: 454 LQKAITFRDSNIVDVNSYGELKEVIAEGK-WARGPWSASDVDELKVKEETSATIRCFPFD 278
           L++A   RDS       Y E K  + E   +A+G W   +  E K+KE+T  TIRC PF 
Sbjct: 397 LERARAHRDSKTFTFKDYEEFKRKMIETPGFAKGMWCGEEECEAKIKEDTGVTIRCIPFV 456

Query: 277 QPGGAKKCFMTGNPTDEVAIFAKSY 203
           Q    + C   G P   +   AK+Y
Sbjct: 457 QENLGETCQFCGKPAKHMVYLAKAY 481

>SYP_MYCLE (Q9Z5I7) Prolyl-tRNA synthetase (EC 6.1.1.15) (Proline--tRNA|
           ligase) (ProRS)
          Length = 480

 Score = 77.0 bits (188), Expect = 4e-14
 Identities = 50/146 (34%), Positives = 78/146 (53%), Gaps = 2/146 (1%)
 Frame = -1

Query: 634 EMKGVPIRIELGPRDVKNRSVVLSRRDVPGKQGKEFGISMEPSILVDHIKGRLEEIQASL 455
           E++GVPIR+ELGPRD++  + V+ RR +  K  +   I+  P+     + G LEE Q +L
Sbjct: 341 ELRGVPIRLELGPRDLEAGTTVMVRR-IGEKAKQPIAIAAAPT----ELPGILEEFQRTL 395

Query: 454 LQKAITFRDSNIVDVNSYGELKEVIAEGKWARGPWSASDVDELKVKEETSATIRCFPFDQ 275
           L++A  FRD +   V+++      +A G WA      +   E  +K ET+AT RC P   
Sbjct: 396 LERATQFRDDHTTLVDNWDAFATTVATG-WALAIHCGNPECEEDIKAETAATPRCVPRQG 454

Query: 274 PGGAKKCFMTGNPT--DEVAIFAKSY 203
                +C     P+  D+  IFA++Y
Sbjct: 455 APATGRCIRCDAPSAYDKRVIFARAY 480

>SYP_BORBU (O51363) Prolyl-tRNA synthetase (EC 6.1.1.15) (Proline--tRNA|
           ligase) (ProRS)
          Length = 488

 Score = 68.6 bits (166), Expect = 2e-11
 Identities = 49/153 (32%), Positives = 73/153 (47%), Gaps = 9/153 (5%)
 Frame = -1

Query: 634 EMKGVPIRIELGPRDVKNRSVVLSRRDVPGKQGKEFGISMEPSILVDHIKGRLEEIQASL 455
           E KG+PIR+E+G  DV   SV +SRRD    + ++F   +    L+  +K  L+ +Q  L
Sbjct: 340 EFKGIPIRLEVGINDVLLNSVTISRRD----KDRKFKYQISLDSLISKVKVELDLMQKDL 395

Query: 454 LQKAITFRDSNIVDV-----NSYGELKEVIAE-GKWARGPWSASDVDELKVKEETSATIR 293
            Q+A+ FR  N  ++     +SY   K  + +   +    W  S   E  +K ET ATIR
Sbjct: 396 FQRALNFRILNTKEIFRSSKDSYETFKAYVNDYSGFVLSCWCGSLNCENIIKNETKATIR 455

Query: 292 CFPFD---QPGGAKKCFMTGNPTDEVAIFAKSY 203
           C P D   +      C    +      +FAKSY
Sbjct: 456 CIPDDFKARDLTGMTCIYCSSKAKYFVLFAKSY 488

>YHI0_YEAST (P38708) Putative prolyl-tRNA synthetase YHR020W (EC 6.1.1.15)|
            (Proline--tRNA ligase) (ProRS)
          Length = 688

 Score = 63.5 bits (153), Expect = 5e-10
 Identities = 48/164 (29%), Positives = 72/164 (43%), Gaps = 20/164 (12%)
 Frame = -1

Query: 634  EMKGVPIRIELGPRDVKNRSVVLSRRDVPGKQGKEFGISMEPSILVDHIKGRLEEIQASL 455
            E+KG+PIRIELGP+D++   VV+ RR+      K++ +S +   L   I   LEE+Q  L
Sbjct: 531  ELKGIPIRIELGPKDIEKNQVVVVRRN----DSKKYVVSFDE--LEARIPEILEEMQGDL 584

Query: 454  LQKAITFRDSNIVDVNSYGELKEVIAEGKWARGPWSA-----SDVDELKVKEE------- 311
             +KA    D++ V VN +      + +      PW        D+ E   K++       
Sbjct: 585  FKKAKELFDTHRVIVNEWSGFVPALNKKNVILAPWCGVMECEEDIKESSAKKDDGEEFEE 644

Query: 310  ------TSATIRCFPFDQP--GGAKKCFMTGNPTDEVAIFAKSY 203
                    A   C PFDQP     +KC           +F +SY
Sbjct: 645  DDKAPSMGAKSLCIPFDQPVLNEGQKCIKCERIAVNYCMFGRSY 688

>SYEP_HUMAN (P07814) Bifunctional aminoacyl-tRNA synthetase [Includes:|
            Glutamyl-tRNA synthetase (EC 6.1.1.17) (Glutamate--tRNA
            ligase); Prolyl-tRNA synthetase (EC 6.1.1.15)
            (Proline--tRNA ligase)]
          Length = 1440

 Score = 59.7 bits (143), Expect = 7e-09
 Identities = 46/162 (28%), Positives = 76/162 (46%), Gaps = 18/162 (11%)
 Frame = -1

Query: 634  EMKGVPIRIELGPRDVKNRSVVLSRRDVPGKQGKEFGISMEPSILVDHIKGRLEEIQASL 455
            E+KGVPIR+E+GPRD+K+   V  RRD   K      +++  +     ++  LE+IQ +L
Sbjct: 1287 ELKGVPIRLEVGPRDMKSCQFVAVRRDTGEK------LTVAENEAETKLQAILEDIQVTL 1340

Query: 454  LQKAITFRDSNIVDVNSYGELKEVIAEGKWARGPWSASDVDELKVKEETS---------- 305
              +A     +++V  N+  + ++++  GK  + P+      E  +K+ T+          
Sbjct: 1341 FTRASEDLKTHMVVANTMEDFQKILDSGKIVQIPFCGEIDCEDWIKKTTARDQDLEPGAP 1400

Query: 304  ---ATIRCFPFD-----QPGGAKKCFMTGNPTDEVAIFAKSY 203
               A   C PF      QPG   KC    NP     +F +SY
Sbjct: 1401 SMGAKSLCIPFKPLCELQPGA--KCVCGKNPAKYYTLFGRSY 1440

>SYEP_MOUSE (Q8CGC7) Bifunctional aminoacyl-tRNA synthetase [Includes:|
            Glutamyl-tRNA synthetase (EC 6.1.1.17) (Glutamate--tRNA
            ligase); Prolyl-tRNA synthetase (EC 6.1.1.15)
            (Proline--tRNA ligase)]
          Length = 1512

 Score = 56.2 bits (134), Expect = 8e-08
 Identities = 46/162 (28%), Positives = 74/162 (45%), Gaps = 18/162 (11%)
 Frame = -1

Query: 634  EMKGVPIRIELGPRDVKNRSVVLSRRDVPGKQGKEFGISMEPSILVDHIKGRLEEIQASL 455
            E+KGVP+R+E+GPRD+K+   V  RRD   K      +++        ++  LE+IQ +L
Sbjct: 1359 ELKGVPVRLEVGPRDMKSCQFVAVRRDTGEK------LTIAEKEAEAKLEKVLEDIQLNL 1412

Query: 454  LQKAITFRDSNIVDVNSYGELKEVIAEGKWARGPW-------------SASDVDELKVKE 314
              +A     +++V  N+  + ++V+  GK A+ P+             +A D D      
Sbjct: 1413 FTRASEDLKTHMVVSNTLEDFQKVLDAGKVAQIPFCGEIDCEDWIKKMTARDQDVEPGAP 1472

Query: 313  ETSATIRCFPFD-----QPGGAKKCFMTGNPTDEVAIFAKSY 203
               A   C PF+     QPG    C    NP     +F +SY
Sbjct: 1473 SMGAKSLCIPFNPLCELQPGA--MCVCGKNPAKFYTLFGRSY 1512

>SYEP_DROME (P28668) Bifunctional aminoacyl-tRNA synthetase [Includes:|
            Glutamyl-tRNA synthetase (EC 6.1.1.17) (Glutamate--tRNA
            ligase); Prolyl-tRNA synthetase (EC 6.1.1.15)
            (Proline--tRNA ligase)]
          Length = 1714

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 44/162 (27%), Positives = 71/162 (43%), Gaps = 18/162 (11%)
 Frame = -1

Query: 634  EMKGVPIRIELGPRDVKNRSVVLSRRDVPGKQGKEFGISMEPSILVDHIKGRLEEIQASL 455
            E+KGVP+R+E+GP+D+K + +V  RRD   K      I++  + +   I   LE I  S+
Sbjct: 1559 ELKGVPLRLEVGPKDLKAQQLVAVRRDTVEK------ITIPLADVEKKIPALLETIHESM 1612

Query: 454  LQKAITFRDSNIVDVNSYGELKEVIAEGKWARGPWSASDVDELKVKEETS---------- 305
            L KA     S+   V ++ +    + +      P+      E K+K +++          
Sbjct: 1613 LNKAQEDMTSHTKKVTNWTDFCGFLEQKNILLAPFCGEISCEDKIKADSARGEEAEPGAP 1672

Query: 304  ---ATIRCFPFDQP---GGAKKCFMTG--NPTDEVAIFAKSY 203
               A   C PFDQP     + KC      N      +F +SY
Sbjct: 1673 AMGAKSLCIPFDQPAPIAASDKCINPSCTNKPKFYTLFGRSY 1714

>SYP_METTH (O26708) Prolyl-tRNA synthetase (EC 6.1.1.15) (Proline--tRNA|
           ligase) (ProRS)
          Length = 482

 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 42/128 (32%), Positives = 64/128 (50%), Gaps = 13/128 (10%)
 Frame = -1

Query: 634 EMKGVPIRIELGPRDVKNRSVVLSRRDVPGK-----QGKEFGISMEPSILVDHIKGRLEE 470
           EM+GVP+R+E+GPRD++  + V+SRRD   K     QG E  +      ++++++ R  E
Sbjct: 346 EMRGVPLRVEIGPRDLEKGAAVISRRDTGEKVTADLQGIEETLRELMKDILENLRTRAWE 405

Query: 469 IQASLLQKAITFRD-SNIVDVNSYGELKEVIAEGKWARGPWSASDVDE------LKVKEE 311
              S +++A T  + S IVD       K  I    W        DV+E      L ++EE
Sbjct: 406 RMESEIREAETLEEASRIVDE------KRGIISFMWCGEEECGMDVEEKVRVDILGIQEE 459

Query: 310 TSAT-IRC 290
            S T I C
Sbjct: 460 GSGTCINC 467

>SYPC_METJA (Q58635) Bifunctional aminoacyl-tRNA synthetase (ProCysRS)|
           (AATS-CysPro) [Includes: Prolyl-tRNA synthetase (EC
           6.1.1.15) (Proline--tRNA ligase); Cysteinyl-tRNA
           synthetase (EC 6.1.1.16) (Cysteine--tRNA ligase)]
          Length = 455

 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 31/116 (26%), Positives = 63/116 (54%), Gaps = 3/116 (2%)
 Frame = -1

Query: 634 EMKGVPIRIELGPRDVKNRSVVLSRRDVPGKQGKEFGISMEPSILVDHIKGRLEEIQASL 455
           E+KGVP+RIE+GP+D++N+ + L RRD   K        ++ + L++ ++  L  I  ++
Sbjct: 329 EIKGVPLRIEVGPKDIENKKITLFRRDTMEK------FQVDETQLMEVVEKTLNNIMENI 382

Query: 454 LQKAITFRDSNIV---DVNSYGELKEVIAEGKWARGPWSASDVDELKVKEETSATI 296
             +A    ++ I    D+N   E+K +++E +         ++   +++E+  ATI
Sbjct: 383 KNRAWEKFENFITILEDINP-DEIKNILSEKRGVILVPFKEEIYNEELEEKVEATI 437

>SYP_ARCFU (O28664) Prolyl-tRNA synthetase (EC 6.1.1.15) (Proline--tRNA|
           ligase) (ProRS)
          Length = 575

 Score = 38.5 bits (88), Expect = 0.017
 Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 2/85 (2%)
 Frame = -1

Query: 634 EMKGVPIRIELGPRDVKNRSVVLSRRDVPGKQGKEFGISMEPSIL--VDHIKGRLEEIQA 461
           E+KGVPIR E+GPRD +    V+S RD   K         E  +L     +K RL    A
Sbjct: 437 ELKGVPIRFEIGPRDAEKGVAVVSFRDEKRKFEVPLDEVDEGKVLEWARELKQRLRNAAA 496

Query: 460 SLLQKAITFRDSNIVDVNSYGELKE 386
             + + + F       V + GE++E
Sbjct: 497 ERMAEKVKF-------VENTGEIEE 514

>APT_DEBHA (Q6BZF9) Adenine phosphoribosyltransferase (EC 2.4.2.7) (APRT)|
          Length = 186

 Score = 30.4 bits (67), Expect = 4.6
 Identities = 14/39 (35%), Positives = 24/39 (61%), Gaps = 2/39 (5%)
 Frame = +1

Query: 448 SVEEMPEFPLDGLLYDP--PILMVP*IFQTPFLAFQGHL 558
           S+++ P FP +G+L++   P+   P +FQ    AFQ H+
Sbjct: 16  SLKQFPNFPSEGILFEDFLPVFTKPDLFQKLVRAFQLHV 54

>CH60_BRUSU (Q8FX87) 60 kDa chaperonin (Protein Cpn60) (groEL protein)|
          Length = 546

 Score = 30.4 bits (67), Expect = 4.6
 Identities = 30/117 (25%), Positives = 42/117 (35%), Gaps = 6/117 (5%)
 Frame = -1

Query: 535 KEFGISMEPSILVDHIKGRLEEIQASLLQKAITFRDSN------IVDVNSYGELKEVIAE 374
           K     M P  L   I   + E+ A LL+KA     S        +  N   E+ ++IAE
Sbjct: 105 KAVAAGMNPMDLKRGIDLAVNEVVAELLKKAKKINTSEEVAQVGTISANGEAEIGKMIAE 164

Query: 373 GKWARGPWSASDVDELKVKEETSATIRCFPFDQPGGAKKCFMTGNPTDEVAIFAKSY 203
                G      V+E K  E     +    FD+  G    +   NP   VA    +Y
Sbjct: 165 AMQKVGNEGVITVEEAKTAETELEVVEGMQFDR--GYLSPYFVTNPEKMVADLEDAY 219

>CH60_BRUME (Q8YB53) 60 kDa chaperonin (Protein Cpn60) (groEL protein)|
          Length = 546

 Score = 30.4 bits (67), Expect = 4.6
 Identities = 30/117 (25%), Positives = 42/117 (35%), Gaps = 6/117 (5%)
 Frame = -1

Query: 535 KEFGISMEPSILVDHIKGRLEEIQASLLQKAITFRDSN------IVDVNSYGELKEVIAE 374
           K     M P  L   I   + E+ A LL+KA     S        +  N   E+ ++IAE
Sbjct: 105 KAVAAGMNPMDLKRGIDLAVNEVVAELLKKAKKINTSEEVAQVGTISANGEAEIGKMIAE 164

Query: 373 GKWARGPWSASDVDELKVKEETSATIRCFPFDQPGGAKKCFMTGNPTDEVAIFAKSY 203
                G      V+E K  E     +    FD+  G    +   NP   VA    +Y
Sbjct: 165 AMQKVGNEGVITVEEAKTAETELEVVEGMQFDR--GYLSPYFVTNPEKMVADLEDAY 219

>CH60_BRUAB (P25967) 60 kDa chaperonin (Protein Cpn60) (groEL protein) (Hsp60)|
           (BA60K)
          Length = 546

 Score = 30.4 bits (67), Expect = 4.6
 Identities = 30/117 (25%), Positives = 42/117 (35%), Gaps = 6/117 (5%)
 Frame = -1

Query: 535 KEFGISMEPSILVDHIKGRLEEIQASLLQKAITFRDSN------IVDVNSYGELKEVIAE 374
           K     M P  L   I   + E+ A LL+KA     S        +  N   E+ ++IAE
Sbjct: 105 KAVAAGMNPMDLKRGIDLAVNEVVAELLKKAKKINTSEEVAQVGTISANGEAEIGKMIAE 164

Query: 373 GKWARGPWSASDVDELKVKEETSATIRCFPFDQPGGAKKCFMTGNPTDEVAIFAKSY 203
                G      V+E K  E     +    FD+  G    +   NP   VA    +Y
Sbjct: 165 AMQKVGNEGVITVEEAKTAETELEVVEGMQFDR--GYLSPYFVTNPEKMVADLEDAY 219

>PUF3_YEAST (Q07807) Protein PUF3|
          Length = 879

 Score = 30.4 bits (67), Expect = 4.6
 Identities = 14/42 (33%), Positives = 25/42 (59%), Gaps = 5/42 (11%)
 Frame = -1

Query: 532 EFGISMEPSILVDHIKGRLEEIQASL-----LQKAITFRDSN 422
           EFG  ++ + LVD  KG ++++   +     +QKA+ + DSN
Sbjct: 597 EFGSKIQKNTLVDQFKGNMKQLSLQMYACRVIQKALEYIDSN 638


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 94,736,341
Number of Sequences: 219361
Number of extensions: 1997800
Number of successful extensions: 4287
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 4197
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4281
length of database: 80,573,946
effective HSP length: 107
effective length of database: 57,102,319
effective search space used: 5881538857
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)