>DOCK9_MOUSE (Q8BIK4) Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide|
            exchange factor zizimin 1)
          Length = 2055

 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 39/125 (31%), Positives = 61/125 (48%)
 Frame = -2

Query: 694  EFSPVENAIGMIETRTAALRNELEEPRSSEGDQLPRLQSLQRILQGSVAVQVNSGVLSVC 515
            + +P+E AI  +  + A LR       S+E D +     LQ  LQGSV+VQVN+G L+  
Sbjct: 1930 DLNPIEVAIDEMSKKVAELRQLCS---SAEVDMI----KLQLKLQGSVSVQVNAGPLAYA 1982

Query: 514  TAFLSGEPATRLRSXXXXXXXXXXXEFMAVCKRAIRVHFRLIGEEDQEFHTQLVNGFQSL 335
             AFL      R              +F+  C +A+ V+ RLI E+  E+  ++   ++ +
Sbjct: 1983 RAFLDDTNTKRYPDNKVKLLKEVFRQFVEACGQALAVNERLIKEDQLEYQEEMKANYREM 2042

Query: 334  TAELS 320
              ELS
Sbjct: 2043 AKELS 2047

>DOCK9_HUMAN (Q9BZ29) Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide|
            exchange factor zizimin 1)
          Length = 2069

 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 39/125 (31%), Positives = 61/125 (48%)
 Frame = -2

Query: 694  EFSPVENAIGMIETRTAALRNELEEPRSSEGDQLPRLQSLQRILQGSVAVQVNSGVLSVC 515
            + +P+E AI  +  + A LR       S+E D +     LQ  LQGSV+VQVN+G L+  
Sbjct: 1944 DLNPIEVAIDEMSKKVAELRQLCS---SAEVDMI----KLQLKLQGSVSVQVNAGPLAYA 1996

Query: 514  TAFLSGEPATRLRSXXXXXXXXXXXEFMAVCKRAIRVHFRLIGEEDQEFHTQLVNGFQSL 335
             AFL      R              +F+  C +A+ V+ RLI E+  E+  ++   ++ +
Sbjct: 1997 RAFLDDTNTKRYPDNKVKLLKEVFRQFVEACGQALAVNERLIKEDQLEYQEEMKANYREM 2056

Query: 334  TAELS 320
              ELS
Sbjct: 2057 AKELS 2061

>DOCK9_RAT (Q63603) Dedicator of cytokinesis protein 9 (Cdc42 guanine|
           nucleotide exchange factor zizimin 1) (TRG protein)
           (Fragment)
          Length = 720

 Score = 53.9 bits (128), Expect = 5e-07
 Identities = 39/128 (30%), Positives = 61/128 (47%)
 Frame = -2

Query: 694 EFSPVENAIGMIETRTAALRNELEEPRSSEGDQLPRLQSLQRILQGSVAVQVNSGVLSVC 515
           + +P+E AI  +  + A L        S+E D +     LQ  LQGSV+VQVN+G L+  
Sbjct: 513 DLNPIEVAIDEMSKKVAELHQLCS---SAEVDMI----KLQLKLQGSVSVQVNAGPLAYA 565

Query: 514 TAFLSGEPATRLRSXXXXXXXXXXXEFMAVCKRAIRVHFRLIGEEDQEFHTQLVNGFQSL 335
            AFL      R              +F+  C +A+ V+ RLI E+  E+  ++   ++ +
Sbjct: 566 RAFLDDTNTKRYPDNKVKLLKEVFRQFVEACGQALAVNERLIKEDQLEYQEEMKANYREI 625

Query: 334 TAELSHYI 311
             ELS  I
Sbjct: 626 RKELSDII 633

>DOC10_MOUSE (Q8BZN6) Dedicator of cytokinesis protein 10 (Fragment)|
          Length = 1816

 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 40/134 (29%), Positives = 69/134 (51%)
 Frame = -2

Query: 694  EFSPVENAIGMIETRTAALRNELEEPRSSEGDQLPRLQSLQRILQGSVAVQVNSGVLSVC 515
            E +P+E AI  +  + +    EL +  ++E   + RLQ     LQGSV+V+VN+G ++  
Sbjct: 1647 ELNPIEVAIDEMSRKVS----ELNQLCTTEEVDMIRLQLK---LQGSVSVKVNAGPMAYA 1699

Query: 514  TAFLSGEPATRLRSXXXXXXXXXXXEFMAVCKRAIRVHFRLIGEEDQEFHTQLVNGFQSL 335
             AFL    A +              +F   C +A+ V+ RLI E+  E+  +L + ++ +
Sbjct: 1700 RAFLEETNAKKYPDNQVKLLKEIFRQFADACGQALDVNERLIKEDQLEYQEELRSHYKDM 1759

Query: 334  TAELSHYIPAILSE 293
             +ELS    AI++E
Sbjct: 1760 LSELS----AIMNE 1769

>DOC10_HUMAN (Q96BY6) Dedicator of cytokinesis protein 10 (Protein zizimin 3)|
          Length = 2183

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 37/125 (29%), Positives = 63/125 (50%)
 Frame = -2

Query: 694  EFSPVENAIGMIETRTAALRNELEEPRSSEGDQLPRLQSLQRILQGSVAVQVNSGVLSVC 515
            E +P+E AI  +  + +    EL +  + E   + RLQ     LQGSV+V+VN+G ++  
Sbjct: 2022 ELNPIEVAIDEMSKKVS----ELNQLCTMEEVDMIRLQLK---LQGSVSVKVNAGPMAYA 2074

Query: 514  TAFLSGEPATRLRSXXXXXXXXXXXEFMAVCKRAIRVHFRLIGEEDQEFHTQLVNGFQSL 335
             AFL    A +              +F   C +A+ V+ RLI E+  E+  +L + ++ +
Sbjct: 2075 RAFLEETNAKKYPDNQVKLLKEIFRQFADACGQALDVNERLIKEDQLEYQEELRSHYKDM 2134

Query: 334  TAELS 320
             +ELS
Sbjct: 2135 LSELS 2139

>DOCK6_MOUSE (Q8VDR9) Dedicator of cytokinesis protein 6 (Fragment)|
          Length = 849

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 39/133 (29%), Positives = 57/133 (42%)
 Frame = -2

Query: 688  SPVENAIGMIETRTAALRNELEEPRSSEGDQLPRLQSLQRILQGSVAVQVNSGVLSVCTA 509
            +PVE AI  ++ +T  L    E+         P  + LQ +LQGSV   VN G L V   
Sbjct: 702  TPVEVAIEDMQKKTRELAFATEQDP-------PDAKMLQMVLQGSVGPTVNQGPLEVAQV 754

Query: 508  FLSGEPATRLRSXXXXXXXXXXXEFMAVCKRAIRVHFRLIGEEDQEFHTQLVNGFQSLTA 329
            FLS  P                 +F   C+ A+R +  LIG + +E+H +L   +  L  
Sbjct: 755  FLSEIPEDPKLFRHHNKLRLCFKDFCKKCEDALRKNKALIGPDQKEYHRELERHYSRLRE 814

Query: 328  ELSHYIPAILSEL 290
             L   +   L +L
Sbjct: 815  ALQPLLTQRLPQL 827

>DOCK6_HUMAN (Q96HP0) Dedicator of cytokinesis protein 6|
          Length = 2047

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 38/133 (28%), Positives = 57/133 (42%)
 Frame = -2

Query: 688  SPVENAIGMIETRTAALRNELEEPRSSEGDQLPRLQSLQRILQGSVAVQVNSGVLSVCTA 509
            +PVE AI  ++ +T  L    E+         P  + LQ +LQGSV   VN G L V   
Sbjct: 1900 TPVEVAIEDMQKKTRELAFATEQDP-------PDAKMLQMVLQGSVGPTVNQGPLEVAQV 1952

Query: 508  FLSGEPATRLRSXXXXXXXXXXXEFMAVCKRAIRVHFRLIGEEDQEFHTQLVNGFQSLTA 329
            FL+  P                 +F   C+ A+R +  LIG + +E+H +L   +  L  
Sbjct: 1953 FLAEIPEDPKLFRHHNKLRLCFKDFCKKCEDALRKNKALIGPDQKEYHRELERNYCRLRE 2012

Query: 328  ELSHYIPAILSEL 290
             L   +   L +L
Sbjct: 2013 ALQPLLTQRLPQL 2025

>DOCK8_HUMAN (Q8NF50) Dedicator of cytokinesis protein 8|
          Length = 2031

 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 37/133 (27%), Positives = 57/133 (42%)
 Frame = -2

Query: 688  SPVENAIGMIETRTAALRNELEEPRSSEGDQLPRLQSLQRILQGSVAVQVNSGVLSVCTA 509
            +P+E AI  ++ +T  L   + +       + P  + LQ +LQGSV   VN G L V   
Sbjct: 1875 TPIEVAIEDMKKKTLQLAVAINQ-------EPPDAKMLQMVLQGSVGATVNQGPLEVAQV 1927

Query: 508  FLSGEPATRLRSXXXXXXXXXXXEFMAVCKRAIRVHFRLIGEEDQEFHTQLVNGFQSLTA 329
            FL+  PA                EF+  C  A+  + RLI  + +E+  +L   +  L  
Sbjct: 1928 FLAEIPADPKLYRHHNKLRLCFKEFIMRCGEAVEKNKRLITADQREYQQELKKNYNKLKE 1987

Query: 328  ELSHYIPAILSEL 290
             L   I   + EL
Sbjct: 1988 NLRPMIERKIPEL 2000

>DOCK8_MOUSE (Q8C147) Dedicator of cytokinesis protein 8|
          Length = 1037

 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 38/133 (28%), Positives = 56/133 (42%)
 Frame = -2

Query: 688  SPVENAIGMIETRTAALRNELEEPRSSEGDQLPRLQSLQRILQGSVAVQVNSGVLSVCTA 509
            +P+E AI  ++ +T  L     +       + P  + LQ +LQGSV   VN G L V   
Sbjct: 881  TPIEVAIEDMKKKTLQLAVATHQ-------EPPDAKMLQMVLQGSVGATVNQGPLEVAQV 933

Query: 508  FLSGEPATRLRSXXXXXXXXXXXEFMAVCKRAIRVHFRLIGEEDQEFHTQLVNGFQSLTA 329
            FL+  PA                EF+  C  A+  + RLI  E +E+  +L   +  L  
Sbjct: 934  FLAEIPADPKLYRHHNKLRLCFKEFIMRCGEAVEKNRRLITAEQREYQQELKKNYNKLRD 993

Query: 328  ELSHYIPAILSEL 290
             L   I   + EL
Sbjct: 994  SLRPMIERKIPEL 1006

>DOCK7_HUMAN (Q96N67) Dedicator of cytokinesis protein 7|
          Length = 1542

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 36/133 (27%), Positives = 58/133 (43%)
 Frame = -2

Query: 688  SPVENAIGMIETRTAALRNELEEPRSSEGDQLPRLQSLQRILQGSVAVQVNSGVLSVCTA 509
            +P+E AI  ++ +T  L     +  +      P++  LQ +LQGSV   VN G L V   
Sbjct: 1393 TPIEVAIEDMQKKTQELAFATHQDPAD-----PKM--LQMVLQGSVGTTVNQGPLEVAQV 1445

Query: 508  FLSGEPATRLRSXXXXXXXXXXXEFMAVCKRAIRVHFRLIGEEDQEFHTQLVNGFQSLTA 329
            FLS  P+                +F   C+ A+R +  LIG + +E+  +L   +  L  
Sbjct: 1446 FLSEIPSDPKLFRHHNKLRLCFKDFTKRCEDALRKNKSLIGPDQKEYQRELERNYHRLKE 1505

Query: 328  ELSHYIPAILSEL 290
             L   I   + +L
Sbjct: 1506 ALQPLINRKIPQL 1518

>DOCK7_MOUSE (Q8R1A4) Dedicator of cytokinesis protein 7 (Fragment)|
          Length = 727

 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 36/133 (27%), Positives = 57/133 (42%)
 Frame = -2

Query: 688 SPVENAIGMIETRTAALRNELEEPRSSEGDQLPRLQSLQRILQGSVAVQVNSGVLSVCTA 509
           +P+E AI  ++ +T  L     +  +      P++  LQ +LQGSV   VN G L V   
Sbjct: 578 TPIEVAIEDMQKKTQELAFATHQDPAD-----PKM--LQMVLQGSVGTTVNQGPLEVAQV 630

Query: 508 FLSGEPATRLRSXXXXXXXXXXXEFMAVCKRAIRVHFRLIGEEDQEFHTQLVNGFQSLTA 329
           FLS  P                 +F   C+ A+R +  LIG + +E+  +L   +  L  
Sbjct: 631 FLSEIPGDPKLFRHHNKLRLCFKDFTKRCEDALRKNKSLIGPDQKEYQRELERNYHRLKE 690

Query: 328 ELSHYIPAILSEL 290
            L   I   + +L
Sbjct: 691 ALQPLINRKIPQL 703

>DOCK3_HUMAN (Q8IZD9) Dedicator of cytokinesis protein 3 (Modifier of cell|
            adhesion) (Presenilin-binding protein) (PBP protein)
          Length = 2030

 Score = 40.0 bits (92), Expect = 0.007
 Identities = 33/141 (23%), Positives = 57/141 (40%), Gaps = 10/141 (7%)
 Frame = -2

Query: 694  EFSPVENAIGMIETRTAALRNELEEPRSSEGDQLPRLQSLQRILQGSVAVQVNSGVLSVC 515
            E SP+ENAI ++E +   LR+ + + +  +      +  L   L G +   VN G+    
Sbjct: 1503 EVSPLENAIQVVENKNQELRSLISQYQHKQVH--GNINLLSMCLNGVIDAAVNGGIARYQ 1560

Query: 514  TAFL----------SGEPATRLRSXXXXXXXXXXXEFMAVCKRAIRVHFRLIGEEDQEFH 365
             AF             E  T+L+              + V    + VH + +  E +  H
Sbjct: 1561 EAFFDKDYINKHPGDAEKITQLKELMQEQ--------VHVLGVGLAVHEKFVHPEMRPLH 1612

Query: 364  TQLVNGFQSLTAELSHYIPAI 302
             +L++ FQ + A L H  P +
Sbjct: 1613 KKLIDQFQMMRASLYHEFPGL 1633

>DOCK3_MOUSE (Q8CIQ7) Dedicator of cytokinesis protein 3 (Modifier of cell|
            adhesion) (Presenilin-binding protein) (PBP protein)
          Length = 2027

 Score = 39.7 bits (91), Expect = 0.009
 Identities = 32/133 (24%), Positives = 56/133 (42%), Gaps = 2/133 (1%)
 Frame = -2

Query: 694  EFSPVENAIGMIETRTAALRNELEEPRSSEGDQLPRLQSLQRILQGSVAVQVNSGVLSVC 515
            E SP+ENAI ++E +   LR  + + +  +      +  L   L G +   VN G+    
Sbjct: 1500 EVSPLENAIQVVENKNQELRALISQYQHKQVH--GNINLLSMCLNGVIDAAVNGGIARYQ 1557

Query: 514  TAFLSGEPATRL--RSXXXXXXXXXXXEFMAVCKRAIRVHFRLIGEEDQEFHTQLVNGFQ 341
             AF   +  T+    +           E + V    + VH + +  E +  H +L++ FQ
Sbjct: 1558 EAFFDKDYITKHPGDAEKISQLKELMQEQVHVLGVGLAVHEKFVHPEMRPLHKKLIDQFQ 1617

Query: 340  SLTAELSHYIPAI 302
             + A L H  P +
Sbjct: 1618 MMRASLYHEFPGL 1630

>DOCK4_HUMAN (Q8N1I0) Dedicator of cytokinesis protein 4|
          Length = 1966

 Score = 37.0 bits (84), Expect = 0.057
 Identities = 31/134 (23%), Positives = 55/134 (41%), Gaps = 10/134 (7%)
 Frame = -2

Query: 694  EFSPVENAIGMIETRTAALRNELEEPRSSEGDQLPRLQSLQRILQGSVAVQVNSGVLSVC 515
            E SP+ENAI ++E +   L+  + + ++    Q+  +  L   L G +   VN GV    
Sbjct: 1465 EMSPLENAIEVLENKNQQLKTLISQCQTR---QMQNINPLTMCLNGVIDAAVNGGVSRYQ 1521

Query: 514  TAFL----------SGEPATRLRSXXXXXXXXXXXEFMAVCKRAIRVHFRLIGEEDQEFH 365
             AF            GE   RLR                + +  + VH + + ++ +  H
Sbjct: 1522 EAFFVKEYILSHPEDGEKIARLRELMLEQA--------QILEFGLAVHEKFVPQDMRPLH 1573

Query: 364  TQLVNGFQSLTAEL 323
             +LV+ F  + + L
Sbjct: 1574 KKLVDQFFVMKSSL 1587

>DOCK4_MOUSE (P59764) Dedicator of cytokinesis protein 4|
          Length = 1978

 Score = 36.6 bits (83), Expect = 0.075
 Identities = 30/127 (23%), Positives = 52/127 (40%), Gaps = 10/127 (7%)
 Frame = -2

Query: 694  EFSPVENAIGMIETRTAALRNELEEPRSSEGDQLPRLQSLQRILQGSVAVQVNSGVLSVC 515
            E SP+ENAI ++E +   L+  + + ++    Q+  +  L   L G +   VN GV    
Sbjct: 1474 EMSPLENAIEVLENKNQQLKTLISQCQTR---QMQNINPLTMCLNGVIDAAVNGGVSRYQ 1530

Query: 514  TAFL----------SGEPATRLRSXXXXXXXXXXXEFMAVCKRAIRVHFRLIGEEDQEFH 365
             AF            GE   RLR                + +  + VH + + ++ +  H
Sbjct: 1531 EAFFVKDYILSHPEDGEKIARLRELMLEQA--------QILEFGLAVHEKFVPQDMRPLH 1582

Query: 364  TQLVNGF 344
             +LV+ F
Sbjct: 1583 KKLVDQF 1589

>SRBP2_CRIGR (Q60429) Sterol regulatory element-binding protein 2 (SREBP-2)|
           (Sterol regulatory element-binding transcription factor
           2)
          Length = 1139

 Score = 32.0 bits (71), Expect = 1.8
 Identities = 21/57 (36%), Positives = 32/57 (56%), Gaps = 2/57 (3%)
 Frame = +1

Query: 148 AEMQRPVSSQTIQPKLLE--I*TFGADPQLKKSTNHSHAT*LPATFATVIAPKVWQV 312
           A++Q  V+S  +QP  ++  + T  A   L ++ N +  T  PAT  TV AP+V QV
Sbjct: 181 AQVQSLVTSSQVQPVTIQQQVQTVQAQRVLTQTANGTLQTLAPATVQTVAAPQVQQV 237

>SRBP2_HUMAN (Q12772) Sterol regulatory element-binding protein 2 (SREBP-2)|
           (Sterol regulatory element-binding transcription factor
           2)
          Length = 1141

 Score = 30.4 bits (67), Expect = 5.4
 Identities = 20/56 (35%), Positives = 31/56 (55%), Gaps = 2/56 (3%)
 Frame = +1

Query: 151 EMQRPVSSQTIQPKLLE--I*TFGADPQLKKSTNHSHAT*LPATFATVIAPKVWQV 312
           ++Q  V+S  +QP  ++  + T  A   L ++ N +  T  PAT  TV AP+V QV
Sbjct: 184 QVQSLVTSSQVQPVTIQQQVQTVQAQRVLTQTANGTLQTLAPATVQTVAAPQVQQV 239

>KUP1_AGRT5 (Q8UHH1) Probable potassium transport system protein kup 1|
          Length = 639

 Score = 29.6 bits (65), Expect = 9.1
 Identities = 18/56 (32%), Positives = 25/56 (44%)
 Frame = -1

Query: 347 VSISYC*AFSLYTCHTFGAMTVAKVAGS*VACEWLVDFFSWGSAPNVHISSSFGCI 180
           + IS C    L+   + G  TVAK  G  +   W   F   G A  +HI+  FG +
Sbjct: 158 IPISVCILIGLFAIQSHGTGTVAKFFGP-ITAVW---FLVMGGAGLIHIADDFGIL 209

>MEGF6_RAT (O88281) Multiple epidermal growth factor-like domains 6 precursor|
           (EGF-like domain-containing protein 3) (Multiple
           EGF-like domain protein 3)
          Length = 1574

 Score = 29.6 bits (65), Expect = 9.1
 Identities = 22/83 (26%), Positives = 30/83 (36%), Gaps = 6/83 (7%)
 Frame = -1

Query: 560 RKCGCSGQQWCIKRMHRFLVWRACNQAPVSRTATA-DCCIA*I-----HGCLQACNPCAF 399
           R+ GC+ Q WCI +  R + + +  Q   +   T   CC          GCL   + CA 
Sbjct: 70  RRTGCAQQAWCIGQERRTVYYMSYRQVYATEARTVFRCCPGWSQKPGQEGCLSDVDECA- 128

Query: 398 *IDRGRRPGVPHATCQWVSISYC 330
                   G     C  V   YC
Sbjct: 129 ----SANGGCEGPCCNTVGGFYC 147

>FBLN2_HUMAN (P98095) Fibulin-2 precursor|
          Length = 1184

 Score = 29.6 bits (65), Expect = 9.1
 Identities = 14/44 (31%), Positives = 20/44 (45%)
 Frame = -1

Query: 572 KDTPRKCGCSGQQWCIKRMHRFLVWRACNQAPVSRTATADCCIA 441
           KD    C  +GQQW I       +  +  +  V RTA   CC++
Sbjct: 439 KDLIETCCAAGQQWAIDNDECLEIPESGTEDNVCRTAQRHCCVS 482


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 94,957,917
Number of Sequences: 219361
Number of extensions: 1908890
Number of successful extensions: 4643
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 4504
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4641
length of database: 80,573,946
effective HSP length: 109
effective length of database: 56,663,597
effective search space used: 6912958834
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)