ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | rbags34i17 |
|---|---|
| Clone Library Name | barley_pub |
>UBP3_ARATH (O24454) Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.1.2.15)| (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3) (Deubiquitinating enzyme 3) (AtUBP3) Length = 371 Score = 300 bits (767), Expect = 4e-81 Identities = 144/161 (89%), Positives = 151/161 (93%), Gaps = 1/161 (0%) Frame = -2 Query: 757 DIEQNSSITSCLKNFSSTETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRFKY 578 DIEQNSSITSCLKNFSSTETL+AEDKFFCDKCCSLQEAQKRMKIKK PHILVIHLKRFKY Sbjct: 205 DIEQNSSITSCLKNFSSTETLHAEDKFFCDKCCSLQEAQKRMKIKKPPHILVIHLKRFKY 264 Query: 577 IEQLGRYKKLSYRVVFPMELKMGSTSDD-VDTEYSLFAVVVHVGSGPNHGHYVSLVKSHN 401 IEQLGRYKKLSYRVVFP+ELK+ +T + D EYSLFAVVVHVGSGPNHGHYVSLVKSHN Sbjct: 265 IEQLGRYKKLSYRVVFPLELKLSNTVEPYADVEYSLFAVVVHVGSGPNHGHYVSLVKSHN 324 Query: 400 HWLFFDDENVEMVEESTLQTFFGSSHEYSGNTDHGYILFYE 278 HWLFFDDENVEM+EES +QTFFGSS EYS NTDHGYILFYE Sbjct: 325 HWLFFDDENVEMIEESAVQTFFGSSQEYSSNTDHGYILFYE 365
>UBP4_ARATH (Q8LAM0) Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.1.2.15)| (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Deubiquitinating enzyme 4) (AtUBP4) Length = 365 Score = 296 bits (759), Expect = 4e-80 Identities = 142/161 (88%), Positives = 152/161 (94%), Gaps = 1/161 (0%) Frame = -2 Query: 757 DIEQNSSITSCLKNFSSTETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRFKY 578 DIEQNSSITSCLKNFSSTETL+AEDKFFCDKCCSLQEAQKRMKIKK PHILVIHLKRFKY Sbjct: 200 DIEQNSSITSCLKNFSSTETLHAEDKFFCDKCCSLQEAQKRMKIKKPPHILVIHLKRFKY 259 Query: 577 IEQLGRYKKLSYRVVFPMELKMGSTSDD-VDTEYSLFAVVVHVGSGPNHGHYVSLVKSHN 401 +EQLGRYKKLSYRVVFP+ELK+ +T D+ VD EYSLFAVVVHVGSGPNHGHYVSLVKSHN Sbjct: 260 MEQLGRYKKLSYRVVFPLELKLSNTVDEYVDIEYSLFAVVVHVGSGPNHGHYVSLVKSHN 319 Query: 400 HWLFFDDENVEMVEESTLQTFFGSSHEYSGNTDHGYILFYE 278 HWLFFDDE+VE++EES +QTFFGSS EYS NTDHGYIL YE Sbjct: 320 HWLFFDDESVEIIEESAVQTFFGSSQEYSSNTDHGYILLYE 360
>UBP46_MOUSE (P62069) Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.1.2.15)| (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (Deubiquitinating enzyme 46) Length = 366 Score = 210 bits (535), Expect = 3e-54 Identities = 96/163 (58%), Positives = 128/163 (78%), Gaps = 3/163 (1%) Frame = -2 Query: 757 DIEQNSSITSCLKNFSSTETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRFKY 578 D+EQN+SIT CL++FS+TETL +E K++C+ CCS QEAQKRM++KK P IL +HLKRFKY Sbjct: 201 DVEQNTSITHCLRDFSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPMILALHLKRFKY 260 Query: 577 IEQLGRYKKLSYRVVFPMELKMGSTSDD---VDTEYSLFAVVVHVGSGPNHGHYVSLVKS 407 +EQL RY KLSYRVVFP+EL++ +TS D +D Y L AVVVH GSGPN GHY+++VKS Sbjct: 261 MEQLHRYTKLSYRVVFPLELRLFNTSSDAVNLDRMYDLVAVVVHCGSGPNRGHYITIVKS 320 Query: 406 HNHWLFFDDENVEMVEESTLQTFFGSSHEYSGNTDHGYILFYE 278 H WL FDD+ VE ++ ++ F+G + + S N++ GYILFY+ Sbjct: 321 HGFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQ 363
>UBP46_HUMAN (P62068) Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.1.2.15)| (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (Deubiquitinating enzyme 46) Length = 366 Score = 210 bits (535), Expect = 3e-54 Identities = 96/163 (58%), Positives = 128/163 (78%), Gaps = 3/163 (1%) Frame = -2 Query: 757 DIEQNSSITSCLKNFSSTETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRFKY 578 D+EQN+SIT CL++FS+TETL +E K++C+ CCS QEAQKRM++KK P IL +HLKRFKY Sbjct: 201 DVEQNTSITHCLRDFSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPMILALHLKRFKY 260 Query: 577 IEQLGRYKKLSYRVVFPMELKMGSTSDD---VDTEYSLFAVVVHVGSGPNHGHYVSLVKS 407 +EQL RY KLSYRVVFP+EL++ +TS D +D Y L AVVVH GSGPN GHY+++VKS Sbjct: 261 MEQLHRYTKLSYRVVFPLELRLFNTSSDAVNLDRMYDLVAVVVHCGSGPNRGHYITIVKS 320 Query: 406 HNHWLFFDDENVEMVEESTLQTFFGSSHEYSGNTDHGYILFYE 278 H WL FDD+ VE ++ ++ F+G + + S N++ GYILFY+ Sbjct: 321 HGFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQ 363
>UBP12_HUMAN (O75317) Ubiquitin carboxyl-terminal hydrolase 12 (EC 3.1.2.15)| (Ubiquitin thioesterase 12) (Ubiquitin-specific-processing protease 12) (Deubiquitinating enzyme 12) (Ubiquitin hydrolyzing enzyme 1) Length = 355 Score = 202 bits (515), Expect = 7e-52 Identities = 94/163 (57%), Positives = 126/163 (77%), Gaps = 3/163 (1%) Frame = -2 Query: 757 DIEQNSSITSCLKNFSSTETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRFKY 578 D+EQN+SIT CL+ FS+TETL +E K++C++C S QEA KRMK+KK P IL +HLKRFKY Sbjct: 190 DVEQNTSITHCLRGFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPMILALHLKRFKY 249 Query: 577 IEQLGRYKKLSYRVVFPMELKMGSTSDDV---DTEYSLFAVVVHVGSGPNHGHYVSLVKS 407 ++QL RY KLSYRVVFP+EL++ +TS D D Y L AVVVH GSGPN GHY+++VKS Sbjct: 250 MDQLHRYTKLSYRVVFPLELRLFNTSGDATNPDRMYDLVAVVVHCGSGPNRGHYIAIVKS 309 Query: 406 HNHWLFFDDENVEMVEESTLQTFFGSSHEYSGNTDHGYILFYE 278 H+ WL FDD+ VE ++ ++ F+G + + S N++ GYILFY+ Sbjct: 310 HDFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQ 352
>UBPX_CAEEL (P34547) Probable ubiquitin carboxyl-terminal hydrolase R10E11.3| (EC 3.1.2.15) (Ubiquitin thioesterase) (Ubiquitin-specific processing protease) (Deubiquitinating enzyme) Length = 410 Score = 175 bits (443), Expect = 2e-43 Identities = 83/147 (56%), Positives = 110/147 (74%), Gaps = 3/147 (2%) Frame = -2 Query: 757 DIEQNSSITSCLKNFSSTETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRFKY 578 D+EQN+SI+ CL+ FS TETL + K+FC+ C S QEAQKRM+IKK P +L +HLKRFK+ Sbjct: 230 DVEQNTSISHCLRVFSETETLCGDQKYFCETCSSKQEAQKRMRIKKPPQLLALHLKRFKF 289 Query: 577 IEQLGRYKKLSYRVVFPMELKMGSTSDDV---DTEYSLFAVVVHVGSGPNHGHYVSLVKS 407 +E L R+ KLSYRVVFP+EL++ + SDD D Y L A VVH G+ PN GHY++LVKS Sbjct: 290 VEPLNRHTKLSYRVVFPLELRLFNVSDDAEYGDRMYDLVATVVHCGATPNRGHYITLVKS 349 Query: 406 HNHWLFFDDENVEMVEESTLQTFFGSS 326 ++ WL FDD+ VE +E S+++ F G S Sbjct: 350 NSFWLVFDDDIVEKLEVSSMEEFSGMS 376
>UBP9_SCHPO (Q9P7V9) Probable ubiquitin carboxyl-terminal hydrolase 9 (EC| 3.1.2.15) (Ubiquitin thioesterase 9) (Ubiquitin-specific processing protease 9) (Deubiquitinating enzyme 9) Length = 585 Score = 159 bits (402), Expect = 9e-39 Identities = 81/163 (49%), Positives = 114/163 (69%), Gaps = 4/163 (2%) Frame = -2 Query: 757 DIEQNSSITSCLKNFSSTETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRFKY 578 DIE ++S+TSCL++FS++E L++++KF CD C SLQEA+KRMKIKK P IL +HLKRFKY Sbjct: 263 DIENHTSVTSCLRSFSASEMLSSKNKFHCDVCKSLQEAEKRMKIKKLPKILSLHLKRFKY 322 Query: 577 IEQLGRYKKLSYRVVFPMELKMGSTSDDVDTE---YSLFAVVVHVGSGPNHGHYVSLVKS 407 E + KL Y +VF E+++ +T++D + Y L +V+VHVG GP+ GHYVS+V++ Sbjct: 323 NETQEGHDKLFYTIVFTNEMRLFTTTEDAENAERMYYLSSVIVHVGGGPHRGHYVSIVRT 382 Query: 406 HNH-WLFFDDENVEMVEESTLQTFFGSSHEYSGNTDHGYILFY 281 + W+ FDDENV V E+ LQ FFG + Y+LFY Sbjct: 383 KTYGWVLFDDENVTPVNENYLQRFFGDQPGQA----TAYVLFY 421
>UBP9_YEAST (P39967) Ubiquitin carboxyl-terminal hydrolase 9 (EC 3.1.2.15)| (Ubiquitin thioesterase 9) (Ubiquitin-specific-processing protease 9) (Deubiquitinating enzyme 9) Length = 754 Score = 132 bits (333), Expect = 9e-31 Identities = 65/160 (40%), Positives = 101/160 (63%), Gaps = 2/160 (1%) Frame = -2 Query: 751 EQNSSITSCLKNFSSTETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRFKYIE 572 ++ + I LK++ E LN +KF+C+KC LQEA++ + +K+ PHIL +HLKRFKY E Sbjct: 510 DEETDIQKMLKSYHQREMLNGVNKFYCNKCYGLQEAERMVGLKQLPHILSLHLKRFKYSE 569 Query: 571 QLGRYKKLSYRVVFPMELKMGST-SDDVDTEYSLFAVVVHVGSGPNHGHYVSLVKSHNH- 398 + KL ++++P+ L + ST + V +Y L VV+H+GSGP HGHYV + ++ Sbjct: 570 EQKSNIKLFNKILYPLTLDVSSTFNTSVYKKYELSGVVIHMGSGPQHGHYVCICRNEKFG 629 Query: 397 WLFFDDENVEMVEESTLQTFFGSSHEYSGNTDHGYILFYE 278 WL +DDE VE ++E T+ F G + G+ Y+LFY+ Sbjct: 630 WLLYDDETVESIKEETVLQFTG----HPGDQTTAYVLFYK 665
>UBP13_YEAST (P38187) Ubiquitin carboxyl-terminal hydrolase 13 (EC 3.1.2.15)| (Ubiquitin thioesterase 13) (Ubiquitin-specific-processing protease 13) (Deubiquitinating enzyme 13) Length = 688 Score = 126 bits (317), Expect = 6e-29 Identities = 63/144 (43%), Positives = 88/144 (61%), Gaps = 2/144 (1%) Frame = -2 Query: 751 EQNSSITSCLKNFSSTETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRFKYIE 572 ++ + I LK++ E LN +KF+CD+CC LQEA++ + +K+ P L +HLKRFKY E Sbjct: 511 DEETDIQEILKSYHQREMLNGSNKFYCDECCGLQEAERLVGLKQLPDTLTLHLKRFKYSE 570 Query: 571 QLGRYKKLSYRVVFPMELKM-GSTSDDVDTEYSLFAVVVHVGSGPNHGHYVSLVKSHNH- 398 + KL + +P+ L + S + V +Y L +VVH+G GP HGHYVSL K Sbjct: 571 KQNCNIKLFNNIHYPLTLNVCSSINSKVCQKYELAGIVVHMGGGPQHGHYVSLCKHEKFG 630 Query: 397 WLFFDDENVEMVEESTLQTFFGSS 326 WL FDDE VE V+E T+ F G S Sbjct: 631 WLLFDDETVEAVKEETVLEFTGES 654
>UBP3_HUMAN (Q9Y6I4) Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.1.2.15)| (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3) (Deubiquitinating enzyme 3) Length = 521 Score = 81.6 bits (200), Expect = 2e-15 Identities = 46/138 (33%), Positives = 67/138 (48%), Gaps = 7/138 (5%) Frame = -2 Query: 739 SITSCLKNFSSTETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRFKYIEQLGR 560 S+ CL++F+ E L+ + + C KC Q++ K+ I+K P +L +HLKRF + L Sbjct: 364 SLRDCLRSFTDLEELDETELYMCHKCKKKQKSTKKFWIQKLPKVLCLHLKRFHWTAYL-- 421 Query: 559 YKKLSYRVVFPME-------LKMGSTSDDVDTEYSLFAVVVHVGSGPNHGHYVSLVKSHN 401 K+ V FP+ L S Y L AVVVH GSG GHY + Sbjct: 422 RNKVDTYVEFPLRGLDMKWYLLEPENSGPESCLYDLAAVVVHHGSGVGSGHYTAYATHEG 481 Query: 400 HWLFFDDENVEMVEESTL 347 W F+D V + +E T+ Sbjct: 482 RWFHFNDSTVTLTDEETV 499
>UBP22_HUMAN (Q9UPT9) Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15)| (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22) Length = 525 Score = 80.1 bits (196), Expect = 7e-15 Identities = 55/177 (31%), Positives = 88/177 (49%), Gaps = 19/177 (10%) Frame = -2 Query: 754 IEQNSSITSCLKNFSSTETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRFKYI 575 + +++T CL+ F+ E L + K C C S QE+ K++ +KK P + HLKRF++ Sbjct: 356 VSGTTTLTDCLRRFTRPEHLGSSAKIKCSGCHSYQESTKQLTMKKLPIVACFHLKRFEHS 415 Query: 574 EQLGRYKKLSYRVVFPMELKM------------------GSTSDDVDTEYSLFAVVVHVG 449 +L R K++ V FP+EL M + S + D +YSLFAVV H G Sbjct: 416 AKLRR--KITTYVSFPLELDMTPFMASSKESRMNGQYQQPTDSLNNDNKYSLFAVVNHQG 473 Query: 448 SGPNHGHYVSLVKSH-NHWLFFDDENVEMVEESTLQTFFGSSHEYSGNTDHGYILFY 281 + GHY S ++ H + W DD ++ +++++ S GY+LFY Sbjct: 474 T-LESGHYTSFIRQHKDQWFKCDD---AIITKASIKDVLDS---------EGYLLFY 517
>UBP3_MOUSE (Q91W36) Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.1.2.15)| (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3) (Deubiquitinating enzyme 3) Length = 520 Score = 79.3 bits (194), Expect = 1e-14 Identities = 51/160 (31%), Positives = 71/160 (44%), Gaps = 7/160 (4%) Frame = -2 Query: 739 SITSCLKNFSSTETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRFKYIEQLGR 560 S+ CL++F+ E L+ + + C KC Q++ K+ I+K P L +HLKRF + L Sbjct: 363 SLRDCLRSFTDLEELDETELYMCHKCKKKQKSTKKFWIQKLPKALCLHLKRFHWTAYL-- 420 Query: 559 YKKLSYRVVFPME-------LKMGSTSDDVDTEYSLFAVVVHVGSGPNHGHYVSLVKSHN 401 K+ V FP+ L S Y L AVVVH GSG GHY + Sbjct: 421 RNKVDTYVQFPLRGLDMKCYLLEPENSGPDSCLYDLAAVVVHHGSGVGSGHYTAYAVHEG 480 Query: 400 HWLFFDDENVEMVEESTLQTFFGSSHEYSGNTDHGYILFY 281 W F+D V + +E T+ YILFY Sbjct: 481 RWFHFNDSTVTVTDEETV------------GKAKAYILFY 508
>UBP22_MOUSE (Q5DU02) Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15)| (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22) Length = 525 Score = 79.0 bits (193), Expect = 2e-14 Identities = 55/173 (31%), Positives = 86/173 (49%), Gaps = 19/173 (10%) Frame = -2 Query: 742 SSITSCLKNFSSTETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRFKYIEQLG 563 +++T CL+ F+ E L + K C C S QE+ K++ +KK P + HLKRF++ +L Sbjct: 360 TTLTDCLRRFTRPEHLGSSAKIKCSGCHSYQESTKQLTMKKLPIVACFHLKRFEHSAKLR 419 Query: 562 RYKKLSYRVVFPMELKMGS------------------TSDDVDTEYSLFAVVVHVGSGPN 437 R K++ V FP+EL M S + D +YSLFAVV H G+ Sbjct: 420 R--KITTYVSFPLELDMTPFMASSKESRMNGQYQQPLDSLNNDNKYSLFAVVNHQGT-LE 476 Query: 436 HGHYVSLVKSH-NHWLFFDDENVEMVEESTLQTFFGSSHEYSGNTDHGYILFY 281 GHY S ++ H + W DD ++ +++++ S GY+LFY Sbjct: 477 SGHYTSFIRQHKDQWFKCDD---AIITKASIKDVLDS---------EGYLLFY 517
>UBP21_HUMAN (Q9UK80) Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15)| (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21) (NEDD8-specific protease) Length = 565 Score = 77.4 bits (189), Expect = 4e-14 Identities = 48/157 (30%), Positives = 77/157 (49%), Gaps = 3/157 (1%) Frame = -2 Query: 739 SITSCLKNFSSTETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRFKYIEQLGR 560 S+ C F+ E L +E+ CD+C + K++ +++ P ILV+HL RF G Sbjct: 415 SLRDCFNLFTKEEELESENAPVCDRCRQKTRSTKKLTVQRFPRILVLHLNRFS--ASRGS 472 Query: 559 YKKLSYRVVFPME-LKMGSTSDDV--DTEYSLFAVVVHVGSGPNHGHYVSLVKSHNHWLF 389 KK S V FP++ L +G + D Y L+A+ H GS ++GHY +L + W Sbjct: 473 IKKSSVGVDFPLQRLSLGDFASDKAGSPVYQLYALCNHSGS-VHYGHYTALCRCQTGWHV 531 Query: 388 FDDENVEMVEESTLQTFFGSSHEYSGNTDHGYILFYE 278 ++D V V E+ + + GY+LFY+ Sbjct: 532 YNDSRVSPVSENQVA------------SSEGYVLFYQ 556
>UBP21_MOUSE (Q9QZL6) Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15)| (Ubiquitin thioesterase 21) (Ubiquitin-specific processing protease 21) (Deubiquitinating enzyme 21) Length = 566 Score = 77.4 bits (189), Expect = 4e-14 Identities = 48/157 (30%), Positives = 77/157 (49%), Gaps = 3/157 (1%) Frame = -2 Query: 739 SITSCLKNFSSTETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRFKYIEQLGR 560 S+ C F+ E L +E+ CD+C + K++ +++ P ILV+HL RF G Sbjct: 416 SLRDCFSLFTKEEELESENAPVCDRCRQKTRSTKKLTVQRFPRILVLHLNRFS--TSRGS 473 Query: 559 YKKLSYRVVFPME-LKMGSTSDDV--DTEYSLFAVVVHVGSGPNHGHYVSLVKSHNHWLF 389 KK S V FP++ L +G + D Y L+A+ H GS ++GHY +L + W Sbjct: 474 IKKSSVGVDFPLQRLSLGDFASDKAGSPVYQLYALCNHSGS-VHYGHYTALCRCQTGWHV 532 Query: 388 FDDENVEMVEESTLQTFFGSSHEYSGNTDHGYILFYE 278 ++D V V E+ + + GY+LFY+ Sbjct: 533 YNDSRVSPVSENQVA------------SSEGYVLFYQ 557
>UBP33_HUMAN (Q8TEY7) Ubiquitin carboxyl-terminal hydrolase 33 (EC 3.1.2.15)| (Ubiquitin thioesterase 33) (Ubiquitin-specific-processing protease 33) (Deubiquitinating enzyme 33) (VHL-interacting deubiquitinating enzyme 1) Length = 942 Score = 76.3 bits (186), Expect = 1e-13 Identities = 50/160 (31%), Positives = 80/160 (50%), Gaps = 7/160 (4%) Frame = -2 Query: 739 SITSCLKNFSSTETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRFKYIEQLGR 560 ++ CL F + + L ++ + C+KC L+ K K++ P IL IHLKRF++ +L Sbjct: 568 TLQDCLAAFFARDELKGDNMYSCEKCKKLRNGVKFCKVQNFPEILCIHLKRFRH--ELMF 625 Query: 559 YKKLSYRVVFPME-----LKMGSTSDDVDTEYSLFAVVVHVGSGPNHGHYVSLVKS--HN 401 K+S V FP+E + S Y L +V+ H G+ + GHY++ ++ +N Sbjct: 626 STKISTHVSFPLEGLDLQPFLAKDSPAQIVTYDLLSVICHHGTA-SSGHYIAYCRNNLNN 684 Query: 400 HWLFFDDENVEMVEESTLQTFFGSSHEYSGNTDHGYILFY 281 W FDD++V V EST+Q Y+LFY Sbjct: 685 LWYEFDDQSVTEVSESTVQ------------NAEAYVLFY 712
>UBP51_HUMAN (Q70EK9) Ubiquitin carboxyl-terminal hydrolase 51 (EC 3.1.2.15)| (Ubiquitin thioesterase 51) (Ubiquitin-specific-processing protease 51) (Deubiquitinating enzyme 51) Length = 711 Score = 75.5 bits (184), Expect = 2e-13 Identities = 52/171 (30%), Positives = 87/171 (50%), Gaps = 18/171 (10%) Frame = -2 Query: 739 SITSCLKNFSSTETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRFKYIEQLGR 560 S+T CL+ F+ E L + K C+ C S QE+ K++ +KK P + HLKRF+++ + + Sbjct: 548 SLTDCLQWFTRPEHLGSSAKIKCNSCQSYQESTKQLTMKKLPIVACFHLKRFEHVGK--Q 605 Query: 559 YKKLSYRVVFPMELKM----GSTSDD-------------VDTEYSLFAVVVHVGSGPNHG 431 +K++ + FP+EL M ST + + +YSLFAV+ H G+ G Sbjct: 606 RRKINTFISFPLELDMTPFLASTKESRMKEGQPPTDCVPNENKYSLFAVINHHGT-LESG 664 Query: 430 HYVSLVKSH-NHWLFFDDENVEMVEESTLQTFFGSSHEYSGNTDHGYILFY 281 HY S ++ + W DD ++ ++T++ S GY+LFY Sbjct: 665 HYTSFIRQQKDQWFSCDD---AIITKATIEDLLYS---------EGYLLFY 703
>UBP4_HUMAN (Q13107) Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.1.2.15)| (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Deubiquitinating enzyme 4) (Ubiquitous nuclear protein homolog) Length = 963 Score = 74.7 bits (182), Expect = 3e-13 Identities = 52/162 (32%), Positives = 76/162 (46%), Gaps = 8/162 (4%) Frame = -2 Query: 739 SITSCLKNFSSTETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRFKYIEQLGR 560 ++ C++ F++ ETL D ++C C Q+A K+ + P ILV+HLKRF Y R Sbjct: 777 ALRDCIELFTTMETLGEHDPWYCPNCKKHQQATKKFDLWSLPKILVVHLKRFSY----NR 832 Query: 559 Y--KKLSYRVVFPME-LKMGSTSDDVDTE---YSLFAVVVHVGSGPNHGHYVSLVKS--H 404 Y KL V FP+ L M ++ Y L AV H G+ GHY + K+ + Sbjct: 833 YWRDKLDTVVEFPIRGLNMSEFVCNLSARPYVYDLIAVSNHYGA-MGVGHYTAYAKNKLN 891 Query: 403 NHWLFFDDENVEMVEESTLQTFFGSSHEYSGNTDHGYILFYE 278 W +FDD NV + E + T Y+LFY+ Sbjct: 892 GKWYYFDDSNVSLASEDQIV------------TKAAYVLFYQ 921
>UBP8_MOUSE (Q80U87) Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15)| (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (mUBPy) Length = 1080 Score = 73.9 bits (180), Expect = 5e-13 Identities = 52/160 (32%), Positives = 83/160 (51%), Gaps = 7/160 (4%) Frame = -2 Query: 739 SITSCLKNFSSTETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRFKYIEQLGR 560 ++ CL+ FS E L ++F+C C + +++ K+++I K P +L++HLKRF Y GR Sbjct: 925 TLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYD---GR 981 Query: 559 YK-KLSYRVVFPME-LKMGS---TSDDVDTEYSLFAVVVHVGSGPNHGHYVSLVK--SHN 401 +K KL V FP+E L + + +Y+LF+V H G G + GHY + K + Sbjct: 982 WKQKLQTSVDFPLENLDLSQYVIGPKNSLKKYNLFSVSNHYG-GLDGGHYTAYCKNAARQ 1040 Query: 400 HWLFFDDENVEMVEESTLQTFFGSSHEYSGNTDHGYILFY 281 W FDD V + S+++ + YILFY Sbjct: 1041 RWFKFDDHEVSDISVSSVR------------SSAAYILFY 1068
>UBP8_HUMAN (P40818) Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15)| (Ubiquitin thioesterase 8) (Ubiquitin-specific processing protease 8) (Deubiquitinating enzyme 8) (hUBPy) Length = 1118 Score = 73.9 bits (180), Expect = 5e-13 Identities = 52/162 (32%), Positives = 84/162 (51%), Gaps = 9/162 (5%) Frame = -2 Query: 739 SITSCLKNFSSTETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRFKYIEQLGR 560 ++ CL+ FS E L ++F+C C + +++ K+++I K P +L++HLKRF Y GR Sbjct: 963 TLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYD---GR 1019 Query: 559 YK-KLSYRVVFPME------LKMGSTSDDVDTEYSLFAVVVHVGSGPNHGHYVSLVK--S 407 +K KL V FP+E +G ++ +Y+LF+V H G G + GHY + K + Sbjct: 1020 WKQKLQTSVDFPLENLDLSQYVIGPKNN--LKKYNLFSVSNHYG-GLDGGHYTAYCKNAA 1076 Query: 406 HNHWLFFDDENVEMVEESTLQTFFGSSHEYSGNTDHGYILFY 281 W FDD V + S+++ + YILFY Sbjct: 1077 RQRWFKFDDHEVSDISVSSVK------------SSAAYILFY 1106
>UBP15_MOUSE (Q8R5H1) Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.1.2.15)| (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Deubiquitinating enzyme 15) Length = 981 Score = 73.6 bits (179), Expect = 6e-13 Identities = 49/159 (30%), Positives = 76/159 (47%), Gaps = 6/159 (3%) Frame = -2 Query: 736 ITSCLKNFSSTETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRFKYIEQLGRY 557 + C++ F++ E L AED ++C C Q+A K++ + P +LV+HLKRF Y + Sbjct: 788 LKDCIELFTTKEKLGAEDPWYCPNCKEHQQATKKLDLWSLPPVLVVHLKRFSYSRYM--R 845 Query: 556 KKLSYRVVFPM-ELKMGS---TSDDVDTEYSLFAVVVHVGSGPNHGHYVSLVKSHN--HW 395 KL V FP+ +L M + Y+L AV H G G GHY + K+ + W Sbjct: 846 DKLDTLVDFPISDLDMSEFLINPNAGPCRYNLIAVSNHYG-GMGGGHYTAFAKNKDDGKW 904 Query: 394 LFFDDENVEMVEESTLQTFFGSSHEYSGNTDHGYILFYE 278 +FDD +V E + + Y+LFY+ Sbjct: 905 YYFDDSSVSTASEDQIV------------SKAAYVLFYQ 931
>UBP15_HUMAN (Q9Y4E8) Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.1.2.15)| (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Deubiquitinating enzyme 15) (Unph-2) (Unph4) Length = 981 Score = 73.6 bits (179), Expect = 6e-13 Identities = 49/159 (30%), Positives = 76/159 (47%), Gaps = 6/159 (3%) Frame = -2 Query: 736 ITSCLKNFSSTETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRFKYIEQLGRY 557 + C++ F++ E L AED ++C C Q+A K++ + P +LV+HLKRF Y + Sbjct: 788 LKDCIELFTTKEKLGAEDPWYCPNCKEHQQATKKLDLWSLPPVLVVHLKRFSYSRYM--R 845 Query: 556 KKLSYRVVFPM-ELKMGS---TSDDVDTEYSLFAVVVHVGSGPNHGHYVSLVKSHN--HW 395 KL V FP+ +L M + Y+L AV H G G GHY + K+ + W Sbjct: 846 DKLDTLVDFPINDLDMSEFLINPNAGPCRYNLIAVSNHYG-GMGGGHYTAFAKNKDDGKW 904 Query: 394 LFFDDENVEMVEESTLQTFFGSSHEYSGNTDHGYILFYE 278 +FDD +V E + + Y+LFY+ Sbjct: 905 YYFDDSSVSTASEDQIV------------SKAAYVLFYQ 931
>UBP11_HUMAN (P51784) Ubiquitin carboxyl-terminal hydrolase 11 (EC 3.1.2.15)| (Ubiquitin thioesterase 11) (Ubiquitin-specific-processing protease 11) (Deubiquitinating enzyme 11) Length = 920 Score = 73.2 bits (178), Expect = 8e-13 Identities = 49/163 (30%), Positives = 78/163 (47%), Gaps = 10/163 (6%) Frame = -2 Query: 736 ITSCLKNFSSTETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRFKYIEQLGRY 557 + C++ F++ ETL E+ ++C C Q A K++ + P IL+IHLKRF Y + Sbjct: 738 LQECIELFTTVETLEKENPWYCPSCKQHQLATKKLDLWMLPEILIIHLKRFSYTK--FSR 795 Query: 556 KKLSYRVVFPME--------LKMGSTSDDVDTEYSLFAVVVHVGSGPNHGHYVSLV--KS 407 +KL V FP+ ++ + S+ +Y L AV H G G GHY + K Sbjct: 796 EKLDTLVEFPIRDLDFSEFVIQPQNESNPELYKYDLIAVSNHYG-GMRDGHYTTFACNKD 854 Query: 406 HNHWLFFDDENVEMVEESTLQTFFGSSHEYSGNTDHGYILFYE 278 W +FDD +V V E+ ++ + Y+LFY+ Sbjct: 855 SGQWHYFDDNSVSPVNENQIE------------SKAAYVLFYQ 885
>UBP4_MOUSE (P35123) Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.1.2.15)| (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Deubiquitinating enzyme 4) (Ubiquitous nuclear protein) Length = 962 Score = 72.8 bits (177), Expect = 1e-12 Identities = 52/162 (32%), Positives = 75/162 (46%), Gaps = 8/162 (4%) Frame = -2 Query: 739 SITSCLKNFSSTETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRFKYIEQLGR 560 ++ C++ F++ ETL D ++C C Q+A K+ + P ILV+HLKRF Y R Sbjct: 776 ALRECIELFTTMETLGEHDPWYCPTCKKHQQATKKFDLWSLPKILVVHLKRFSY----NR 831 Query: 559 Y--KKLSYRVVFPME-LKMGSTSDDVDTE---YSLFAVVVHVGSGPNHGHYVSLVKS--H 404 Y KL V FP+ L M D Y L AV H G+ GHY + K+ + Sbjct: 832 YWRDKLDTVVEFPVRALNMSEFVCDRSARPYVYDLIAVSNHYGA-MGVGHYTAYAKNRLN 890 Query: 403 NHWLFFDDENVEMVEESTLQTFFGSSHEYSGNTDHGYILFYE 278 W +FDD +V + E + T Y+LFY+ Sbjct: 891 GKWYYFDDSSVSLASEDQIV------------TKAAYVLFYQ 920
>UBP11_MOUSE (Q99K46) Ubiquitin carboxyl-terminal hydrolase 11 (EC 3.1.2.15)| (Ubiquitin thioesterase 11) (Ubiquitin-specific-processing protease 11) (Deubiquitinating enzyme 11) (Fragment) Length = 797 Score = 72.8 bits (177), Expect = 1e-12 Identities = 49/163 (30%), Positives = 78/163 (47%), Gaps = 10/163 (6%) Frame = -2 Query: 736 ITSCLKNFSSTETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRFKYIEQLGRY 557 + C+K F++ ETL E+ ++C C Q A K++ + P +L+IHLKRF + ++ R Sbjct: 616 LKECIKLFTTVETLEKENPWYCSSCKQHQLATKKLDLWMLPEVLIIHLKRFSF-SKISR- 673 Query: 556 KKLSYRVVFPME--------LKMGSTSDDVDTEYSLFAVVVHVGSGPNHGHYVSLV--KS 407 +KL V FP+ +K + S +Y L AV H G G GHY + K Sbjct: 674 EKLDTLVQFPIRDLDFSEFVIKPKNESSPDLYKYDLIAVSNHYG-GMRDGHYTTFACNKD 732 Query: 406 HNHWLFFDDENVEMVEESTLQTFFGSSHEYSGNTDHGYILFYE 278 W + DD +V V E+ ++ + Y+LFY+ Sbjct: 733 SGQWHYLDDNSVSPVNENQIE------------SKAAYVLFYQ 763
>UBP4_SCHPO (O60139) Probable ubiquitin carboxyl-terminal hydrolase 4 (EC| 3.1.2.15) (Ubiquitin thioesterase 4) (Ubiquitin-specific processing protease 4) (Deubiquitinating enzyme 4) Length = 438 Score = 72.8 bits (177), Expect = 1e-12 Identities = 55/170 (32%), Positives = 80/170 (47%), Gaps = 10/170 (5%) Frame = -2 Query: 757 DIEQNSSITSCLKNFSSTETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRFKY 578 D+ S+ CL FS+ E L D + C C + A+K + I K P L+I ++RFK Sbjct: 261 DVSHVVSLQECLLKFSAPELLQGHDGWHCPVCKVQRSAKKVIMISKLPEYLIIQIQRFK- 319 Query: 577 IEQLGRYK---------KLSYRVVFPMELKMGSTSDDVDTEYSLFAVVVHVGSGPNHGHY 425 I +GR K ++ +++ P + G + + Y+LFA + H G N GHY Sbjct: 320 ISVMGRKKIDTPLGLSLQIPSKMLVPPSFQSGIGY--IPSNYNLFAFICHYGQLEN-GHY 376 Query: 424 VSLVKSHNHWLFFDDENVEMVEEST-LQTFFGSSHEYSGNTDHGYILFYE 278 +S V +N W DD V V T L+ F SS YILFY+ Sbjct: 377 ISDVLFNNEWCHIDDSIVRTVGGITDLREDFSSS----------YILFYK 416
>UBP20_HUMAN (Q9Y2K6) Ubiquitin carboxyl-terminal hydrolase 20 (EC 3.1.2.15)| (Ubiquitin thioesterase 20) (Ubiquitin-specific-processing protease 20) (Deubiquitinating enzyme 20) Length = 913 Score = 70.9 bits (172), Expect = 4e-12 Identities = 48/162 (29%), Positives = 79/162 (48%), Gaps = 9/162 (5%) Frame = -2 Query: 739 SITSCLKNFSSTETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRFKYIEQLGR 560 ++ CL F + + L ++ + C++C L+ K K+ + P IL IHLKRF++ ++ Sbjct: 537 TLEDCLAAFFAADELKGDNMYSCERCKKLRNGVKYCKVLRLPEILCIHLKRFRH--EVMY 594 Query: 559 YKKLSYRVVFPME-------LKMGSTSDDVDTEYSLFAVVVHVGSGPNHGHYVSLVKS-- 407 K++ V FP+E L TS T Y L +V+ H G+ GHY++ ++ Sbjct: 595 SFKINSHVSFPLEGLDLRPFLAKECTSQ--ITTYDLLSVICHHGTA-GSGHYIAYCQNVI 651 Query: 406 HNHWLFFDDENVEMVEESTLQTFFGSSHEYSGNTDHGYILFY 281 + W FDD+ V V E+ +Q GY+LFY Sbjct: 652 NGQWYEFDDQYVTEVHETVVQ------------NAEGYVLFY 681
>UBP12_SCHPO (O60079) Probable ubiquitin carboxyl-terminal hydrolase 12 (EC| 3.1.2.15) (Ubiquitin thioesterase 12) (Ubiquitin-specific processing protease 12) (Deubiquitinating enzyme 12) Length = 979 Score = 70.5 bits (171), Expect = 5e-12 Identities = 57/173 (32%), Positives = 80/173 (46%), Gaps = 14/173 (8%) Frame = -2 Query: 757 DIEQNSSIT--SCLKNFSSTETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRF 584 D E + +IT CL F TE L ED ++C C ++A K+M+I + P IL+ HLKRF Sbjct: 818 DSEDSRTITLNDCLDEFEKTEQLGEEDPWYCPTCKEFRQASKQMEIWRCPEILIFHLKRF 877 Query: 583 KYIEQLGRYKKLSYRVVFP-----MELKMG----STSDDVDTEYSLFAVVVHVGSGPNHG 431 + K+ V FP M ++ G S ++ Y L+AV H G G G Sbjct: 878 SSERRF--RDKIDDLVEFPIDNLDMSMRTGSYKLSEKENPKLIYELYAVDNHYG-GLGGG 934 Query: 430 HYVSLVKSHNHWLF--FDDENVEMV-EESTLQTFFGSSHEYSGNTDHGYILFY 281 HY + K+ ++ F FDD V V E T+ T Y+LFY Sbjct: 935 HYTAFAKNPDNGQFYCFDDSRVTPVCPEETV-------------TSAAYLLFY 974
>UBP12_YEAST (P39538) Ubiquitin carboxyl-terminal hydrolase 12 (EC 3.1.2.15)| (Ubiquitin thioesterase 12) (Ubiquitin-specific-processing protease 12) (Deubiquitinating enzyme 12) Length = 1254 Score = 69.7 bits (169), Expect = 9e-12 Identities = 53/164 (32%), Positives = 79/164 (48%), Gaps = 7/164 (4%) Frame = -2 Query: 751 EQNSSITSCLKNFSSTETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRFKYIE 572 E+ ++ CL+ FS E L D ++C C ++A K++++ P IL+IHLKRF+ Sbjct: 959 ERTITLDDCLQLFSKPEILGLTDSWYCPTCKEHRQATKQIQLWNTPDILLIHLKRFE--S 1016 Query: 571 QLGRYKKLSYRVVFPM-ELKMGS----TSDDVDTEYSLFAVVVHVGSGPNHGHYVSLVK- 410 Q K+ V FP+ +L + D Y L+AV H G G GHY + VK Sbjct: 1017 QRSFSDKIDATVNFPITDLDLSRYVVYKDDPRGLIYDLYAVDNHYG-GLGGGHYTAYVKN 1075 Query: 409 -SHNHWLFFDDENVEMVEESTLQTFFGSSHEYSGNTDHGYILFY 281 + N W +FDD V E + + GS+ Y+LFY Sbjct: 1076 FADNKWYYFDDSRV--TETAPENSIAGSA----------YLLFY 1107
>UBP35_HUMAN (Q9P2H5) Ubiquitin carboxyl-terminal hydrolase 35 (EC 3.1.2.15)| (Ubiquitin thioesterase 35) (Ubiquitin-specific-processing protease 35) (Deubiquitinating enzyme 35) Length = 1017 Score = 69.3 bits (168), Expect = 1e-11 Identities = 48/177 (27%), Positives = 78/177 (44%), Gaps = 20/177 (11%) Frame = -2 Query: 751 EQNSSITSCLKNFSSTETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRFKYIE 572 E + S+ + F S E L AE++++C+ C SLQ+A+K +++ + P L++ L RF + Sbjct: 755 EGSRSVLDLVNYFLSPEKLTAENRYYCESCASLQDAEKVVELSQGPCYLILTLLRFSFDL 814 Query: 571 QLGRYKKLSYRVVFPMELKMGSTSDDVDTEYSLFAVVVHVGSGPNHGHYVSLVKS----- 407 + R +K+ V P+ L++ + Y L +VVVH G GHY + Sbjct: 815 RTMRRRKILDDVSIPLLLRL-PLAGGRGQAYDLCSVVVHSGVSSESGHYYCYAREGAARP 873 Query: 406 ------------HNHWLFFDDENV---EMVEESTLQTFFGSSHEYSGNTDHGYILFY 281 N W F+D V S + +FF D Y+LFY Sbjct: 874 AASLGTADRPEPENQWYLFNDTRVSFSSFESVSNVTSFFPK--------DTAYVLFY 922
>UBP10_YEAST (P53874) Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15)| (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10) (Disrupter of telomere silencing protein 4) Length = 792 Score = 68.9 bits (167), Expect = 2e-11 Identities = 40/134 (29%), Positives = 68/134 (50%), Gaps = 6/134 (4%) Frame = -2 Query: 739 SITSCLKNFSSTETLNAEDK---FFCDKCCSLQEAQKRMKIKKAPHILVIHLKRFKYIEQ 569 SI +K+F + E + + + + C+KC A K I +AP L++HLK+F++ Sbjct: 585 SIEKSIKDFFNPELIKVDKEQKGYVCEKCHKTTNAVKHSSILRAPETLLVHLKKFRFNGT 644 Query: 568 LGRYKKLSYRVVFPMELKMGS--TSDDVDTEYSLFAVVVHVGSGPNHGHYVSLVKS-HNH 398 K+ V +PM L + S ++ +Y L +VVVH G + GHY++ K Sbjct: 645 SS--SKMKQAVSYPMFLDLTEYCESKELPVKYQLLSVVVHEGRSLSSGHYIAHCKQPDGS 702 Query: 397 WLFFDDENVEMVEE 356 W +DDE + ++ E Sbjct: 703 WATYDDEYINIISE 716
>UBP5_ARATH (O22207) Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15)| (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (AtUBP5) Length = 924 Score = 68.9 bits (167), Expect = 2e-11 Identities = 46/160 (28%), Positives = 78/160 (48%), Gaps = 7/160 (4%) Frame = -2 Query: 739 SITSCLKNFSSTETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRFKYIEQLGR 560 S+ +CL+ F E L ++ +FC +C ++A K++ + + P +LVIHLKRF Y + Sbjct: 769 SLYACLEAFLREEPLVPDEMWFCPQCNERRQASKKLDLWRLPEVLVIHLKRFSYSRSMKH 828 Query: 559 YKKLSYRVVFP---MELKMGSTSDDVDTE--YSLFAVVVHVGSGPNHGHYVSLVK--SHN 401 KL V FP ++L + ++ Y L+A+ H G G GHY + +K + Sbjct: 829 --KLETFVNFPIHDLDLTKYVANKNLSQPQLYELYALTNHYG-GMGSGHYTAHIKLLDDS 885 Query: 400 HWLFFDDENVEMVEESTLQTFFGSSHEYSGNTDHGYILFY 281 W FDD ++ + E ++ + Y+LFY Sbjct: 886 RWYNFDDSHISHINEDDVK------------SGAAYVLFY 913
>UBP19_HUMAN (O94966) Ubiquitin carboxyl-terminal hydrolase 19 (EC 3.1.2.15)| (Ubiquitin thioesterase 19) (Ubiquitin-specific-processing protease 19) (Deubiquitinating enzyme 19) (Zinc finger MYND domain-containing protein 9) (Fragment) Length = 1371 Score = 68.2 bits (165), Expect = 3e-11 Identities = 47/168 (27%), Positives = 81/168 (48%), Gaps = 15/168 (8%) Frame = -2 Query: 739 SITSCLKNFSSTETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRFKYIEQLGR 560 ++ CL F+ E L E+ ++C +C +EA K++ + + P++L++ LKRF + + R Sbjct: 1112 TLDQCLNLFTRPEVLAPEEAWYCPQCKQHREASKQLLLWRLPNVLIVQLKRFSFRSFIWR 1171 Query: 559 YKKLSYRVVFPM------ELKMGSTSDDVDTEYSLFAVVVHVGSGPNHGHYVSLVKSHNH 398 K++ V FP+ + +G + + + Y L+AV+ H G G GHY + + N Sbjct: 1172 -DKINDLVEFPVRNLDLSKFCIGQKEEQLPS-YDLYAVINHYG-GMIGGHYTACARLPND 1228 Query: 397 ---------WLFFDDENVEMVEESTLQTFFGSSHEYSGNTDHGYILFY 281 W FDD V V+ES + T + Y+LFY Sbjct: 1229 RSSQRSDVGWRLFDDSTVTTVDESQVV------------TRYAYVLFY 1264
>UBP2_CHICK (O57429) Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.1.2.15)| (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) (Deubiquitinating enzyme 2) (41 kDa ubiquitin-specific protease) Length = 357 Score = 67.8 bits (164), Expect = 4e-11 Identities = 52/159 (32%), Positives = 79/159 (49%), Gaps = 5/159 (3%) Frame = -2 Query: 739 SITSCLKNFSSTETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRFKYIEQLGR 560 ++ CL+ F+ + L+ ++K C +C + K+ I+K P ILV+HLKRF E R Sbjct: 206 TLMDCLRLFTKEDVLDGDEKPTCCRCKARTRCTKKFSIQKFPKILVLHLKRFS--EARIR 263 Query: 559 YKKLSYRVVFP---MELKMGSTSDDVDTEYSLFAVVVHVGSGPNHGHYVSLVKS--HNHW 395 KL+ V FP ++L+ ++ Y+L+AV H G+ GHY + KS + W Sbjct: 264 ASKLTTFVNFPLKDLDLREFASQSCNHAVYNLYAVSNHSGTTMG-GHYTAYCKSPISSEW 322 Query: 394 LFFDDENVEMVEESTLQTFFGSSHEYSGNTDHGYILFYE 278 F+D V T SSH S + Y+LFYE Sbjct: 323 HSFNDSRV---------TPMSSSHVRSSD---AYLLFYE 349
>UBPL_MIMIV (Q5UQR3) Probable ubiquitin carboxyl-terminal hydrolase (EC| 3.1.2.15) (Ubiquitin thioesterase) (Ubiquitin specific-processing protease) (Deubiquitinating enzyme) Length = 468 Score = 66.6 bits (161), Expect = 8e-11 Identities = 51/162 (31%), Positives = 78/162 (48%), Gaps = 9/162 (5%) Frame = -2 Query: 739 SITSCLKNFSSTETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRFKYIEQLGR 560 ++ CL+ + S ETL+A++ + C+ C +A K+ K+ P++LVI KRF + R Sbjct: 315 NVYDCLREYFSQETLDADNLWNCEGCHEKVQAIKKTKLWTTPYVLVIQFKRF----GMTR 370 Query: 559 YKKLSYRVVFPM-ELKMGST------SDDVDTEYSLFAVVVHVGSGPNHGHYVSLVKSHN 401 K + + +PM EL + S D V T+Y L V+ H G G N+GHY + K N Sbjct: 371 IAKDNRFINYPMDELDVSSVICSQQFEDSVQTKYKLQCVINHHG-GLNNGHYFTYSKIEN 429 Query: 400 --HWLFFDDENVEMVEESTLQTFFGSSHEYSGNTDHGYILFY 281 W F+D T+ G + + YILFY Sbjct: 430 TGEWYEFND------------TYTGKVTDNHIVNQNAYILFY 459
>FAF_DROME (P55824) Probable ubiquitin carboxyl-terminal hydrolase FAF (EC| 3.1.2.15) (Ubiquitin thioesterase FAF) (Ubiquitin specific-processing protease FAF) (Deubiquitinating enzyme FAF) (Protein fat facets) Length = 2778 Score = 66.6 bits (161), Expect = 8e-11 Identities = 58/182 (31%), Positives = 75/182 (41%), Gaps = 31/182 (17%) Frame = -2 Query: 757 DIEQNSSITSCLKNFSSTETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRFKY 578 DI +SS+T L+ + E L D + CDKC KR+ +KK P +L I LKRF+Y Sbjct: 1858 DIRNHSSLTESLEQYVKGELLEGADAYHCDKCDKKVVTVKRVCVKKLPPVLAIQLKRFEY 1917 Query: 577 IEQLGRYKKLSYRVVFPMELKM------------GSTSDDVD--------TEYSLFAVVV 458 + K + FP L M G + D T+Y L +VV Sbjct: 1918 DYERVCAIKFNDYFEFPRILDMEPYTVSGLAKLEGEVVEVGDNCQTNVETTKYELTGIVV 1977 Query: 457 HVGSGPNHGHYVSLVKSHN------HWLFFDDENVEMV-----EESTLQTFFGSSHEYSG 311 H G + GHY S + S N W FDD V EE + F G EY G Sbjct: 1978 HSGQA-SGGHYFSYILSKNPANGKCQWYKFDDGEVTECKMHEDEEMKAECFGG---EYMG 2033 Query: 310 NT 305 T Sbjct: 2034 ET 2035
>UBP18_HUMAN (Q9UMW8) Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl| thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease) (hUBP43) Length = 372 Score = 66.2 bits (160), Expect = 1e-10 Identities = 43/169 (25%), Positives = 75/169 (44%), Gaps = 10/169 (5%) Frame = -2 Query: 757 DIEQNSSITSCLKNFSSTETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRF-- 584 D + ++ L F L+++ K FC+ C ++ +K+ P L IHL RF Sbjct: 202 DSKPLKTLEDALHCFFQPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSI 261 Query: 583 ------KYIEQLGRYKKLSYRVVFPMELKMGSTSDDVDTEYSLFAVVVHVGSGPNHGHYV 422 K L + L + + PM+ + + +Y LFAV+ HVG + GHY Sbjct: 262 RNSQTRKICHSLYFPQSLDFSQILPMKRESCDAEEQSGGQYELFAVIAHVGMA-DSGHYC 320 Query: 421 SLVKS--HNHWLFFDDENVEMVEESTLQTFFGSSHEYSGNTDHGYILFY 281 +++ W F+D N+ +V +Q +G+ + + T Y+L Y Sbjct: 321 VYIRNAVDGKWFCFNDSNICLVSWEDIQCTYGNPNYHWQET--AYLLVY 367
>UBP11_CANFA (Q01988) Ubiquitin carboxyl-terminal hydrolase 11 (EC 3.1.2.15)| (Ubiquitin thioesterase 11) (Ubiquitin-specific-processing protease 11) (Deubiquitinating enzyme 11) (Fragment) Length = 445 Score = 65.9 bits (159), Expect = 1e-10 Identities = 49/163 (30%), Positives = 75/163 (46%), Gaps = 10/163 (6%) Frame = -2 Query: 736 ITSCLKNFSSTETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRFKYIEQLGRY 557 + C++ F++ ETL E+ +FC C Q A K++ + P L+IHLKRF Y + Sbjct: 263 LQECIELFTTVETLEKENPWFCPTCKQHQLATKKLDLWMLPETLIIHLKRFSYTK--FSR 320 Query: 556 KKLSYRVVFPME--------LKMGSTSDDVDTEYSLFAVVVHVGSGPNHGHYVSLV--KS 407 +KL V FP+ +K + S +Y L AV H G G GHY + K Sbjct: 321 EKLDTLVEFPIRDLDFSEFVIKPQNESAPELYKYDLIAVSNHYG-GLRDGHYTTFACNKD 379 Query: 406 HNHWLFFDDENVEMVEESTLQTFFGSSHEYSGNTDHGYILFYE 278 +FDD +V V E+ ++ + Y+LFY+ Sbjct: 380 SGQSDYFDDNSVSPVTENQIE------------SKAAYVLFYQ 410
>UBP2_HUMAN (O75604) Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.1.2.15)| (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) (Deubiquitinating enzyme 2) (41 kDa ubiquitin-specific protease) Length = 605 Score = 65.5 bits (158), Expect = 2e-10 Identities = 46/159 (28%), Positives = 79/159 (49%), Gaps = 5/159 (3%) Frame = -2 Query: 739 SITSCLKNFSSTETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRFKYIEQLGR 560 ++ C++ F+ + L+ ++K C +C + K+ I++ P ILV+HLKRF E R Sbjct: 454 TLMDCMRLFTKEDVLDGDEKPTCCRCRGRKRCIKKFSIQRFPKILVLHLKRFS--ESRIR 511 Query: 559 YKKLSYRVVFP---MELKMGSTSDDVDTEYSLFAVVVHVGSGPNHGHYVSLVKS--HNHW 395 KL+ V FP ++L+ ++ + Y+L+AV H G+ GHY + +S W Sbjct: 512 TSKLTTFVNFPLRDLDLREFASENTNHAVYNLYAVSNHSGTTMG-GHYTAYCRSPGTGEW 570 Query: 394 LFFDDENVEMVEESTLQTFFGSSHEYSGNTDHGYILFYE 278 F+D +V + S ++ T Y+LFYE Sbjct: 571 HTFNDSSVTPMSSSQVR------------TSDAYLLFYE 597
>UBP2_MOUSE (O88623) Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.1.2.15)| (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) (Deubiquitinating enzyme 2) (41 kDa ubiquitin-specific protease) Length = 353 Score = 65.1 bits (157), Expect = 2e-10 Identities = 45/159 (28%), Positives = 80/159 (50%), Gaps = 5/159 (3%) Frame = -2 Query: 739 SITSCLKNFSSTETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRFKYIEQLGR 560 ++ C++ F+ + L+ ++K C +C + + K+ +++ P ILV+HLKRF E R Sbjct: 202 TLMDCMRLFTKEDILDGDEKPTCCRCRARKRCIKKFSVQRFPKILVLHLKRFS--ESRIR 259 Query: 559 YKKLSYRVVFP---MELKMGSTSDDVDTEYSLFAVVVHVGSGPNHGHYVSLVKS--HNHW 395 KL+ V FP ++L+ ++ + Y+L+AV H G+ GHY + +S W Sbjct: 260 TSKLTTFVNFPLRDLDLREFASENTNHAVYNLYAVSNHSGTTMG-GHYTAYCRSPVTGEW 318 Query: 394 LFFDDENVEMVEESTLQTFFGSSHEYSGNTDHGYILFYE 278 F+D +V + S ++ T Y+LFYE Sbjct: 319 HTFNDSSVTPMSSSQVR------------TSDAYLLFYE 345
>UBP1_HUMAN (O94782) Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.1.2.15)| (Ubiquitin thioesterase 1) (Ubiquitin-specific processing protease 1) (Deubiquitinating enzyme 1) (hUBP) Length = 785 Score = 64.3 bits (155), Expect = 4e-10 Identities = 35/111 (31%), Positives = 60/111 (54%), Gaps = 6/111 (5%) Frame = -2 Query: 724 LKNFSSTETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRF-----KYIEQLGR 560 + F+S E + EDK+FC+ C EA++ + K P ++ IHLK F ++ G Sbjct: 489 ISQFASVERIVGEDKYFCENCHHYTEAERSLLFDKMPEVITIHLKCFAASGLEFDCYGGG 548 Query: 559 YKKLSYRVVFPMELKMGS-TSDDVDTEYSLFAVVVHVGSGPNHGHYVSLVK 410 K++ ++ P++L + ++ + Y LFAVV+H G + GHY + VK Sbjct: 549 LSKINTPLLTPLKLSLEEWSTKPTNDSYGLFAVVMHSGITISSGHYTASVK 599 Score = 32.0 bits (71), Expect = 2.1 Identities = 20/63 (31%), Positives = 30/63 (47%), Gaps = 2/63 (3%) Frame = -2 Query: 460 VHVGSGPNHGHYV--SLVKSHNHWLFFDDENVEMVEESTLQTFFGSSHEYSGNTDHGYIL 287 +++ N YV SL + WL FDD V++ EE + F S + T Y+L Sbjct: 724 INISGFENKISYVVQSLKEYEGKWLLFDDSEVKVTEE---KDFLNSLSPSTSPTSTPYLL 780 Query: 286 FYE 278 FY+ Sbjct: 781 FYK 783
>UBPW_MOUSE (Q61068) Ubiquitin carboxyl-terminal hydrolase DUB-1 (EC 3.1.2.15)| (Ubiquitin thioesterase DUB-1) (Ubiquitin-specific processing protease DUB-1) (Deubiquitinating enzyme 1) Length = 526 Score = 63.5 bits (153), Expect = 7e-10 Identities = 41/160 (25%), Positives = 72/160 (45%), Gaps = 1/160 (0%) Frame = -2 Query: 757 DIEQNSSITSCLKNFSSTETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRFKY 578 DI S+ L + +E L ++ ++C KC A K + + AP +L++ L RF Sbjct: 199 DISSAQSVKQALWDTEKSEELCGDNAYYCGKCRQKMPASKTLHVHIAPKVLMVVLNRFSA 258 Query: 577 IEQLGRYKKLSYRVVFPMELKMGSTSDDVDTEYSLFAVVVHVGSGPNHGHYVSLVKS-HN 401 +K+SY ++ + + Y+L+AV+VH G+ + GHY VK+ H Sbjct: 259 FTGNKLDRKVSYPEFLDLKPYLSEPTGG-PLPYALYAVLVHDGATSHSGHYFCCVKAGHG 317 Query: 400 HWLFFDDENVEMVEESTLQTFFGSSHEYSGNTDHGYILFY 281 W DD V + +++ ++ Y+LFY Sbjct: 318 KWYKMDDTKVTRCDVTSVL------------NENAYVLFY 345
>UBP38_MOUSE (Q8BW70) Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15)| (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38) Length = 1042 Score = 63.5 bits (153), Expect = 7e-10 Identities = 43/152 (28%), Positives = 66/152 (43%), Gaps = 37/152 (24%) Frame = -2 Query: 751 EQNSSITSCLKNFSSTETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRFKYIE 572 E +S+T L F + E L E++++C+ C SLQ A+K M+I + P L++ L RF Y + Sbjct: 713 ESTTSVTDLLNYFLAPEVLTGENQYYCESCASLQNAEKTMQITEEPEYLILTLLRFSYDQ 772 Query: 571 QLGRYKKLSYRVVFPMELKM------------GSTSDDVD-------------------- 488 + +K+ V P+ L++ S S DVD Sbjct: 773 KYHVRRKILDNVSLPLVLELPVKRTASFSSLSQSWSVDVDFTDINENLPKKLKPSGTEEA 832 Query: 487 -----TEYSLFAVVVHVGSGPNHGHYVSLVKS 407 Y L +VVVH G GHY S ++ Sbjct: 833 FCPKLVPYLLSSVVVHSGVSSESGHYYSYARN 864
>USP9Y_HUMAN (O00507) Probable ubiquitin carboxyl-terminal hydrolase FAF-Y (EC| 3.1.2.15) (Ubiquitin thioesterase FAF-Y) (Ubiquitin-specific-processing protease FAF-Y) (Deubiquitinating enzyme FAF-Y) (Fat facets protein-related, Y-linked) (Ubiquitin-specif Length = 2555 Score = 63.5 bits (153), Expect = 7e-10 Identities = 57/194 (29%), Positives = 80/194 (41%), Gaps = 41/194 (21%) Frame = -2 Query: 757 DIEQNSSITSCLKNFSSTETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRFKY 578 DI + ++ L+ + + L + + C+KC + KR+ IKK P +L I LKRF Y Sbjct: 1745 DIRNHQNLLDSLEQYIKGDLLEGANAYHCEKCDKKVDTVKRLLIKKLPRVLAIQLKRFDY 1804 Query: 577 IEQLGRYKKLSYRVVFPMELKMGSTS---------DDVD-------------------TE 482 + K + FP EL MG + D+V+ T+ Sbjct: 1805 DWERECAIKFNDYFEFPRELDMGPYTVAGVANLERDNVNSENELIEQKEQSDNETAGGTK 1864 Query: 481 YSLFAVVVHVGSGPNHGHYVSLVKSHN-------HWLFFDDENV-----EMVEESTLQTF 338 Y L V+VH G + GHY S + N HW FDD +V + EE Q F Sbjct: 1865 YRLVGVLVHSGQA-SGGHYYSYIIQRNGKDDQTDHWYKFDDGDVTECKMDDDEEMKNQCF 1923 Query: 337 FGSSHEYSGNT-DH 299 G EY G DH Sbjct: 1924 GG---EYMGEVFDH 1934
>UBP18_MOUSE (Q9WTV6) Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl| thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease) Length = 368 Score = 62.0 bits (149), Expect = 2e-09 Identities = 45/169 (26%), Positives = 75/169 (44%), Gaps = 10/169 (5%) Frame = -2 Query: 757 DIEQNSSITSCLKNFSSTETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRF-- 584 D + ++ L+ F + L + D C+ C ++ +K+ P L IHL RF Sbjct: 199 DAKPLKTLEDALRCFVQPKELASSD-MCCETCGEKTPWKQVLKLTHLPQTLTIHLMRFSA 257 Query: 583 ------KYIEQLGRYKKLSYRVVFPMELKMGSTSDDVDTEYSLFAVVVHVGSGPNHGHYV 422 K + + L + V P E +G T + + Y LFAV+ HVG + GHY Sbjct: 258 RNSRTEKICHSVNFPQSLDFSQVLPTEEDLGDTKEQSEIHYELFAVIAHVGMA-DFGHYC 316 Query: 421 SLVKS--HNHWLFFDDENVEMVEESTLQTFFGSSHEYSGNTDHGYILFY 281 + +++ W F+D +V V +Q +G +H Y + Y+L Y Sbjct: 317 AYIRNPVDGKWFCFNDSHVCWVTWKDVQCTYG-NHRYRWR-ETAYLLVY 363
>UBP7_SCHPO (Q9P7S5) Probable ubiquitin carboxyl-terminal hydrolase 7 (EC| 3.1.2.15) (Ubiquitin thioesterase 7) (Ubiquitin-specific processing protease 7) (Deubiquitinating enzyme 7) Length = 875 Score = 62.0 bits (149), Expect = 2e-09 Identities = 49/152 (32%), Positives = 68/152 (44%), Gaps = 35/152 (23%) Frame = -2 Query: 754 IEQNSSITSCLKNFSSTETLNAEDKFFCDKCCS--------------------------L 653 IE+ ++ CLKNF+ E L+ E+ F C+ CC+ Sbjct: 670 IEEPKTLIDCLKNFTHVEELSGENMFACENCCNQPNEVGSPAKGGLTSDNDKYSFNNSVY 729 Query: 652 QEAQKRMKI-KKAPHILVIHLKR-FKYIEQLG--RYKKLSYRVVFPMELK-----MGSTS 500 + A KRM + P + +IHLKR F+ I G KK+S + F EL M Sbjct: 730 RNAYKRMLLDDPLPPVFIIHLKRFFQEISHDGYANPKKISDFIEFEQELDLNEFVMPHLR 789 Query: 499 DDVDTEYSLFAVVVHVGSGPNHGHYVSLVKSH 404 Y LF V+VH G+ N+GHYV+ V SH Sbjct: 790 ASSSFRYRLFGVIVHSGT-LNYGHYVAYVLSH 820
>UBP8_SCHPO (Q09738) Probable ubiquitin carboxyl-terminal hydrolase 8 (EC| 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific processing protease 8) (Deubiquitinating enzyme 8) Length = 449 Score = 61.6 bits (148), Expect = 3e-09 Identities = 42/153 (27%), Positives = 70/153 (45%) Frame = -2 Query: 739 SITSCLKNFSSTETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRFKYIEQLGR 560 ++ CL+ F S E + ++ C C S + A K++ K P + + LKRF+ Sbjct: 299 TLQGCLERFVSKEKV----QYSCHSCGS-KNAIKQLVFDKLPPTICMQLKRFEQ-NNFAM 352 Query: 559 YKKLSYRVVFPMELKMGSTSDDVDTEYSLFAVVVHVGSGPNHGHYVSLVKSHNHWLFFDD 380 K+ +V +P L+M + D +Y L++VV H G+ + GHY++ N W DD Sbjct: 353 STKIDKQVSYPAFLRMRYNFNQDDVDYQLYSVVCHKGT-LDTGHYIAYTYYQNQWFLLDD 411 Query: 379 ENVEMVEESTLQTFFGSSHEYSGNTDHGYILFY 281 + V+ES + Y+LFY Sbjct: 412 TTIVEVKESEVL------------NSQAYLLFY 432
>UBP5_YEAST (P39944) Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15)| (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) Length = 805 Score = 61.2 bits (147), Expect = 3e-09 Identities = 50/174 (28%), Positives = 73/174 (41%), Gaps = 20/174 (11%) Frame = -2 Query: 739 SITSCLKNFSSTETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRFKYIEQLGR 560 +I C + F+ E L ++++ C KC Q + K++KI + P L+I+LKRF + Sbjct: 646 NILDCFREFTKCERLGVDEQWSCPKCLKKQPSTKQLKITRLPKKLIINLKRFD-----NQ 700 Query: 559 YKKLSYRVVFPMELKM-----------GSTSDDVDT-------EYSLFAVVVHVGSGPNH 434 K + V +P L + ++D+ T Y L+ V H GS Sbjct: 701 MNKNNVFVQYPYSLDLTPYWARDFNHEAIVNEDIPTRGQVPPFRYRLYGVACHSGS-LYG 759 Query: 433 GHYVSLVKS--HNHWLFFDDENVEMVEESTLQTFFGSSHEYSGNTDHGYILFYE 278 GHY S V W FFDD + T T F T Y+LFYE Sbjct: 760 GHYTSYVYKGPKKGWYFFDD---SLYRPITFSTEF--------ITPSAYVLFYE 802
>UBP1_SCHPO (Q9USM5) Probable ubiquitin carboxyl-terminal hydrolase 1 (EC| 3.1.2.15) (Ubiquitin thioesterase 1) (Ubiquitin-specific processing protease 1) (Deubiquitinating enzyme 1) Length = 849 Score = 61.2 bits (147), Expect = 3e-09 Identities = 51/171 (29%), Positives = 78/171 (45%), Gaps = 15/171 (8%) Frame = -2 Query: 748 QNSSITSCLKNFSSTETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRFK-YIE 572 ++ ++ CL FS E L+ +D ++C C + + A KR++I + P ILVIHL RF + Sbjct: 688 ESITLEDCLLEFSKPEQLDLQDSWYCPGCKAFRPATKRLEIWRLPKILVIHLNRFSGHGG 747 Query: 571 QLGRYKKLSYRVVFP---MELKMGSTSDDVDTE---------YSLFAVVVHVGSGPNHGH 428 L R +K VV+P + LK + D E Y L+AV H G N GH Sbjct: 748 DLRRRRKRRDLVVYPVFDLNLKQFLSPFIKDHEWLSSQKSMLYDLYAVDNHHGFMSN-GH 806 Query: 427 YVSLVKSHNHWLF--FDDENVEMVEESTLQTFFGSSHEYSGNTDHGYILFY 281 Y + + + F FDD + ++ + T Y+LFY Sbjct: 807 YTAYARDASSQTFFKFDDTAICEIDPEDIV------------TSSAYVLFY 845
>UBP36_HUMAN (Q9P275) Ubiquitin carboxyl-terminal hydrolase 36 (EC 3.1.2.15)| (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36) (Deubiquitinating enzyme 36) Length = 1121 Score = 61.2 bits (147), Expect = 3e-09 Identities = 44/160 (27%), Positives = 68/160 (42%), Gaps = 1/160 (0%) Frame = -2 Query: 757 DIEQNSSITSCLKNFSSTETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRFKY 578 +I Q ++I L+ F + L+ E+ + C KC A KR I + ++L + LKRF Sbjct: 274 EIRQAANIVRALELFVKADVLSGENAYMCAKCKKKVPASKRFTIHRTSNVLTLSLKRFAN 333 Query: 577 IEQLGRYKKLSYRVVFPMELKMGSTSDDVDTEYSLFAVVVHVGSGPNHGHYVSLVKSHN- 401 K + Y + M + D Y L+AV+VH G + GHY VK+ N Sbjct: 334 FSGGKITKDVGYPEFLNIRPYMSQNNGD-PVMYGLYAVLVHSGYSCHAGHYYCYVKASNG 392 Query: 400 HWLFFDDENVEMVEESTLQTFFGSSHEYSGNTDHGYILFY 281 W +D +V S ++ Y+LFY Sbjct: 393 QWYQMND---SLVHSSNVKVVL---------NQQAYVLFY 420
>UBP24_HUMAN (Q9UPU5) Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.1.2.15)| (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24) (Deubiquitinating enzyme 24) Length = 1870 Score = 60.8 bits (146), Expect = 4e-09 Identities = 57/213 (26%), Positives = 83/213 (38%), Gaps = 57/213 (26%) Frame = -2 Query: 745 NSSITSC------LKNFSSTETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRF 584 N +TSC L F E L + ++C+KC + KR IK P +LVIHL RF Sbjct: 1079 NLGVTSCQSLEISLDQFVRGEVLEGSNAYYCEKCKEKRITVKRTCIKSLPSVLVIHLMRF 1138 Query: 583 KYIEQLGRYKKLSYRVVFPMELKM------GSTSDDVDTE-------------------- 482 + + GR K ++ FP L M G D +E Sbjct: 1139 GFDWESGRSIKYDEQIRFPWMLNMEPYTVSGMARQDSSSEVGENGRSVDQGGGGSPRKKV 1198 Query: 481 -----YSLFAVVVHVGSGPNHGHYVSLVKSH-----NHWLFFDD---ENVEMVEESTLQT 341 Y L V+VH G + GHY S +K W F+D E ++ +E+ Sbjct: 1199 ALTENYELVGVIVHSGQA-HAGHYYSFIKDRRGCGKGKWYKFNDTVIEEFDLNDETLEYE 1257 Query: 340 FFGSSH------EYSGNTD------HGYILFYE 278 FG + + + TD + Y+LFY+ Sbjct: 1258 CFGGEYRPKVYDQTNPYTDVRRRYWNAYMLFYQ 1290
>UBP38_HUMAN (Q8NB14) Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15)| (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38) (HP43.8KD) Length = 1042 Score = 60.8 bits (146), Expect = 4e-09 Identities = 42/152 (27%), Positives = 65/152 (42%), Gaps = 37/152 (24%) Frame = -2 Query: 751 EQNSSITSCLKNFSSTETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRFKYIE 572 E S+T L F + E L +++++C+ C SLQ A+K M+I + P L++ L RF Y + Sbjct: 713 ETTPSVTDLLNYFLAPEILTGDNQYYCENCASLQNAEKTMQITEEPEYLILTLLRFSYDQ 772 Query: 571 QLGRYKKLSYRVVFPMELKM------------GSTSDDVD-------------------- 488 + +K+ V P+ L++ S S DVD Sbjct: 773 KYHVRRKILDNVSLPLVLELPVKRITSFSSLSESWSVDVDFTDLSENLAKKLKPSGTDEA 832 Query: 487 -----TEYSLFAVVVHVGSGPNHGHYVSLVKS 407 Y L +VVVH G GHY S ++ Sbjct: 833 SCTKLVPYLLSSVVVHSGISSESGHYYSYARN 864
>USP9X_MOUSE (P70398) Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC| 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X-linked) (Ubiquitin-specif Length = 2559 Score = 60.1 bits (144), Expect = 7e-09 Identities = 61/216 (28%), Positives = 83/216 (38%), Gaps = 56/216 (25%) Frame = -2 Query: 757 DIEQNSSITSCLKNFSSTETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRFKY 578 DI + ++ L+ + + L + + C+KC + KR+ IKK P +L I LKRF Y Sbjct: 1743 DIRNHQNLLDSLEQYVKGDLLEGANAYHCEKCNKKVDTVKRLLIKKLPPVLAIQLKRFDY 1802 Query: 577 IEQLGRYKKLSYRVVFPMELKMGS---------TSDDVD-------------------TE 482 + K + FP EL M D+V+ T+ Sbjct: 1803 DWERECAIKFNDYFEFPRELDMEPYTVAGVAKLEGDNVNPESQLIQQNEQSESEKAGSTK 1862 Query: 481 YSLFAVVVHVGSGPNHGHYVSLV-------KSHNHWLFFDDENV-----EMVEESTLQTF 338 Y L V+VH G + GHY S + N W FDD +V + EE Q F Sbjct: 1863 YRLVGVLVHSGQA-SGGHYYSYIIQRNGGDGEKNRWYKFDDGDVTECKMDDDEEMKTQCF 1921 Query: 337 FGSSHEYSGNT-DH---------------GYILFYE 278 G EY G DH YILFYE Sbjct: 1922 GG---EYMGEVLDHMMKRMSYRRQKRWWNAYILFYE 1954
>UBP42_HUMAN (Q9H9J4) Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15)| (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42) Length = 1325 Score = 60.1 bits (144), Expect = 7e-09 Identities = 42/160 (26%), Positives = 71/160 (44%), Gaps = 1/160 (0%) Frame = -2 Query: 757 DIEQNSSITSCLKNFSSTETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRFKY 578 +I+ S+ L+ F E L+ E+ + C KC + A KR I ++ ++L + LKRF Sbjct: 263 EIKAAQSVNKALEQFVKPEQLDGENSYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRFAN 322 Query: 577 IEQLGRYKKLSYRVVFPMELKMGSTSDDVDTEYSLFAVVVHVGSGPNHGHYVSLVKSHNH 398 K + Y + M + + Y L+AV+VH G + GHY +K+ N Sbjct: 323 FTGGKIAKDVKYPEYLDIRPYMSQPNGE-PIVYVLYAVLVHTGFNCHAGHYFCYIKASNG 381 Query: 397 -WLFFDDENVEMVEESTLQTFFGSSHEYSGNTDHGYILFY 281 W +D +V S +++ + Y+LFY Sbjct: 382 LWYQMND---SIVSTSDIRSVL---------SQQAYVLFY 409
>UBP10_MOUSE (P52479) Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15)| (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10) Length = 792 Score = 60.1 bits (144), Expect = 7e-09 Identities = 36/109 (33%), Positives = 59/109 (54%), Gaps = 11/109 (10%) Frame = -2 Query: 649 EAQKRMKIKKAPHILVIHLKRFKYIEQLGRYKKLSYRVVFPMELKMG---------STSD 497 E +R+ ++K P +LV+HLKRF Y E+ G +KL + +P++L++ + + Sbjct: 662 EVSRRVTLEKLPPVLVLHLKRFVY-EKTGGCQKLVKNIDYPVDLEISRELLSPGIKNKNF 720 Query: 496 DVDTEYSLFAVVVHVGSGPNHGHYVSLV--KSHNHWLFFDDENVEMVEE 356 Y LFAVV H G+ GHY + V N WL DD+ V+++ + Sbjct: 721 KCQRTYRLFAVVYHHGNSATGGHYTTDVFQIGLNGWLRIDDQTVKVINQ 769
>UBP10_HUMAN (Q14694) Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15)| (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10) Length = 798 Score = 60.1 bits (144), Expect = 7e-09 Identities = 38/109 (34%), Positives = 60/109 (55%), Gaps = 11/109 (10%) Frame = -2 Query: 649 EAQKRMKIKKAPHILVIHLKRFKYIEQLGRYKKLSYRVVFPMELKMGS--TSDDVDTE-- 482 E +R+ ++K P +LV+HLKRF Y E+ G +KL + +P++L++ S V + Sbjct: 668 EISRRVTLEKLPPVLVLHLKRFVY-EKTGGCQKLIKNIEYPVDLEISKELLSPGVKNKNF 726 Query: 481 -----YSLFAVVVHVGSGPNHGHYVSLV--KSHNHWLFFDDENVEMVEE 356 Y LFAVV H G+ GHY + V N WL DD+ V+++ + Sbjct: 727 KCHRTYRLFAVVYHHGNSATGGHYTTDVFQIGLNGWLRIDDQTVKVINQ 775
>UBP7_HUMAN (Q93009) Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.1.2.15)| (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease) Length = 1102 Score = 60.1 bits (144), Expect = 7e-09 Identities = 49/159 (30%), Positives = 75/159 (47%), Gaps = 8/159 (5%) Frame = -2 Query: 754 IEQNSSITSCLKNFSSTETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRFKYI 575 I+ +I ++ + E L+ ++K+ + LQEA+K +K P +L + L RF Y Sbjct: 354 IKGKKNIFESFVDYVAVEQLDGDNKYDAGEH-GLQEAEKGVKFLTLPPVLHLQLMRFMYD 412 Query: 574 EQLGRYKKLSYRVVFPMELKMGSTSDDVD----TEYSLFAVVVHVGSGPNH-GHYVSLV- 413 Q + K++ R FP +L + D Y L AV+VH SG NH GHYV + Sbjct: 413 PQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVH--SGDNHGGHYVVYLN 470 Query: 412 -KSHNHWLFFDDENV-EMVEESTLQTFFGSSHEYSGNTD 302 K W FDD+ V +E ++ H Y G+ D Sbjct: 471 PKGDGKWCKFDDDVVSRCTKEEAIE------HNYGGHDD 503
>UBP21_SCHPO (Q9UTT1) Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15)| (Ubiquitin thioesterase 21) (Ubiquitin-specific processing protease 21) (Deubiquitinating enzyme 21) Length = 1129 Score = 59.7 bits (143), Expect = 1e-08 Identities = 44/163 (26%), Positives = 83/163 (50%), Gaps = 13/163 (7%) Frame = -2 Query: 757 DIEQNSSITSCLKNFSSTETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRFKY 578 +++ ++ ++ ETL ++K++ + LQ+A K + + P++L + LKRF Y Sbjct: 369 NVKGMDTLEDSFRDAIQVETLTGDNKYYAEGH-GLQDAHKGIIFESLPNVLQLQLKRFDY 427 Query: 577 IEQLGRYKKLSYRVVFPMELK----MGSTSDDVDTE-YSLFAVVVHVGSGPNHGHYVSLV 413 K++ R FP+E+ + T+D ++ Y L V+VH G + GHY +L+ Sbjct: 428 DMLRDMMVKINDRHEFPLEIDLEPYLSETADKSESHVYVLHGVLVH-GGDLHGGHYYALI 486 Query: 412 K--SHNHWLFFDDENV------EMVEESTLQTFFGSSHEYSGN 308 K ++W FDD+ V E++E++ G + Y+GN Sbjct: 487 KPEKDSNWFKFDDDRVTRATIKEVLEDNYGGEPAGRAKGYNGN 529
>USP9X_HUMAN (Q93008) Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC| 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein related, X-linked) (Ubiquitin-specif Length = 2547 Score = 59.7 bits (143), Expect = 1e-08 Identities = 61/216 (28%), Positives = 83/216 (38%), Gaps = 56/216 (25%) Frame = -2 Query: 757 DIEQNSSITSCLKNFSSTETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRFKY 578 DI + ++ L+ + + L + + C+KC + KR+ IKK P +L I LKRF Y Sbjct: 1736 DIRNHQNLLDSLEQYVKGDLLEGANAYHCEKCNKKVDTVKRLLIKKLPPVLAIQLKRFDY 1795 Query: 577 IEQLGRYKKLSYRVVFPMELKMGS---------TSDDVD-------------------TE 482 + K + FP EL M D+V+ T+ Sbjct: 1796 DWERECAIKFNDYFEFPRELDMEPYTVAGVAKLEGDNVNPESQLIQQSEQSESETAGSTK 1855 Query: 481 YSLFAVVVHVGSGPNHGHYVSLV-------KSHNHWLFFDDENV-----EMVEESTLQTF 338 Y L V+VH G + GHY S + N W FDD +V + EE Q F Sbjct: 1856 YRLVGVLVHSGQA-SGGHYYSYIIQRNGGDGERNRWYKFDDGDVTECKMDDDEEMKNQCF 1914 Query: 337 FGSSHEYSGNT-DH---------------GYILFYE 278 G EY G DH YILFYE Sbjct: 1915 GG---EYMGEVFDHMMKRMSYRRQKRWWNAYILFYE 1947
>UBP47_MOUSE (Q8BY87) Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15)| (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47) Length = 1376 Score = 59.3 bits (142), Expect = 1e-08 Identities = 52/222 (23%), Positives = 86/222 (38%), Gaps = 68/222 (30%) Frame = -2 Query: 742 SSITSCLKNFSSTETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRFKYIEQLG 563 +S+ L F E L+ +++FC++C +A+K ++ P++L + LKRF + Sbjct: 341 ASVEEALHAFIQPEILDGPNQYFCERCKKKCDARKGLRFLHFPYLLTLQLKRFDFDYTTM 400 Query: 562 RYKKLSYRVVFPMELKMG------------------------------------STSDDV 491 KL+ R+ FP EL M ST D V Sbjct: 401 HRIKLNDRMSFPEELDMSTFIDIEDEKSPQTESCTDSGAENEGSCHSDQMSNDFSTDDAV 460 Query: 490 DTE-----------------------YSLFAVVVHVGSGPNHGHYVSLVKSHN--HWLFF 386 D Y LF+V+VH GS GHY + +KS + W F Sbjct: 461 DEGICLESSSGSEKISKPGLEKNSLMYELFSVMVHSGSAAG-GHYYACIKSFSDDQWYSF 519 Query: 385 DDENVEMVEESTLQTFFGSSHEYSG-------NTDHGYILFY 281 +D++V + + ++ G S G ++ + Y+L Y Sbjct: 520 NDQHVSRITQEDIKKTHGGSSGSRGYYSSAFASSTNAYMLIY 561
>UBP4_YEAST (P32571) Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.1.2.15)| (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Deubiquitinating enzyme 4) (Vacuole biogenesis protein SSV7) Length = 926 Score = 58.9 bits (141), Expect = 2e-08 Identities = 44/178 (24%), Positives = 75/178 (42%), Gaps = 23/178 (12%) Frame = -2 Query: 745 NSSITSCLKNFSSTETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRFKYIEQL 566 N +I C + F+ E L ++++ C C Q + K++ I + P L++HLKRF + Sbjct: 760 NITIEDCFREFTKCENLEVDEQWLCPHCEKRQPSTKQLTITRLPRNLIVHLKRFDNL--- 816 Query: 565 GRYKKLSYRVVFPMELKM--------------GSTSDDVDT-------EYSLFAVVVHVG 449 K + V++P L + G D++ +Y L+ V H G Sbjct: 817 --LNKNNDFVIYPFLLDLTPFWANDFDGVFPPGVNDDELPIRGQIPPFKYELYGVACHFG 874 Query: 448 SGPNHGHYVSLVKS--HNHWLFFDDENVEMVEESTLQTFFGSSHEYSGNTDHGYILFY 281 + GHY + VK WL+FDD + V+ ++ + Y+LFY Sbjct: 875 T-LYGGHYTAYVKKGLKKGWLYFDDTKYKPVK-----------NKADAINSNAYVLFY 920
>UBP3_SCHPO (O94269) Probable ubiquitin carboxyl-terminal hydrolase 3 (EC| 3.1.2.15) (Ubiquitin thioesterase 3) (Ubiquitin-specific processing protease 3) (Deubiquitinating enzyme 3) Length = 512 Score = 58.9 bits (141), Expect = 2e-08 Identities = 42/133 (31%), Positives = 62/133 (46%), Gaps = 11/133 (8%) Frame = -2 Query: 646 AQKRMKIKKAPHILVIHLKRFKYIEQLG---RYKKLSY--RVVFPMELKMGSTSDDVDTE 482 A K+M I+ P +L++HLKRF Y G YK ++Y R+ P + S + E Sbjct: 376 ATKQMYIESLPPVLILHLKRFFYEASGGTQKNYKPIAYPARLSIPQNVFSPSVRGSIHPE 435 Query: 481 YSLFAVVVHVGSGPNHGHYVSLVK--SHNHWLFFDDENVEMVEESTLQTFFGSSHEYSGN 308 Y L AVV H G+ + GHY V+ + W DD ++ V ++ S+ Sbjct: 436 YDLNAVVYHHGTSASGGHYTVDVQQLDKSGWFRIDDTHIHRVPIHDVENSELSADPSLSK 495 Query: 307 TDHG----YILFY 281 HG Y+LFY Sbjct: 496 LGHGDRVAYLLFY 508
>UBP49_HUMAN (Q70CQ1) Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15)| (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49) Length = 688 Score = 58.5 bits (140), Expect = 2e-08 Identities = 49/150 (32%), Positives = 69/150 (46%), Gaps = 23/150 (15%) Frame = -2 Query: 736 ITSCLKNFSSTETLNAEDKFFCDKCCS-----------LQEAQKRMKIKKAPHILVIHLK 590 +T L F+ TE L + CD+C S L EA+K++ I + P +L +HLK Sbjct: 496 LTEMLAKFTETEALEGRI-YACDQCNSKRRKSNPKPLVLSEARKQLMIYRLPQVLRLHLK 554 Query: 589 RFKYIEQLGRYKKLSYRVVFPMELKMG--------STSDDVDTEYSLFAVVVHVGSGPNH 434 RF++ + R +K+ VVF L M S+ D Y L AVV+H G G Sbjct: 555 RFRWSGRNHR-EKIGVHVVFDQVLTMEPYCCRDMLSSLDKETFAYDLSAVVMHHGKGFGS 613 Query: 433 GHYVSLV--KSHNHWLFFDDE--NVEMVEE 356 GHY + W+ +D NV VEE Sbjct: 614 GHYTAYCYNTEGGFWVHCNDSKLNVCSVEE 643
>UBP5_SCHPO (Q09879) Probable ubiquitin carboxyl-terminal hydrolase 5 (EC| 3.1.2.15) (Ubiquitin thioesterase 5) (Ubiquitin-specific processing protease 5) (Deubiquitinating enzyme 5) Length = 1108 Score = 58.2 bits (139), Expect = 3e-08 Identities = 42/148 (28%), Positives = 73/148 (49%), Gaps = 13/148 (8%) Frame = -2 Query: 757 DIEQNSSITSCLKNFSSTETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRFKY 578 +++ ++ +++ ETL ++ +F D QEA+K + + P IL + LKRF+Y Sbjct: 352 NVKGMKNLEDSFRSYIQVETLEGDNCYFADTY-GFQEAKKGVIFESFPPILHLQLKRFEY 410 Query: 577 IEQLGRYKKLSYRVVFPMELKMGS-----TSDDVDTEYSLFAVVVHVGSGPNHGHYVSLV 413 + K++ R FP+E + + EY L+ V+VH G N GHY +L+ Sbjct: 411 DFERDMMIKINDRYEFPLEFDAKAFLSPEADQSQNCEYVLYGVLVHSGDLHN-GHYYALL 469 Query: 412 KSHNH--WLFFDDENV------EMVEES 353 K+ W +DD V E++EE+ Sbjct: 470 KTEKDGPWYKYDDTRVTRATLREVLEEN 497
>UBPE_DROME (Q24574) Ubiquitin carboxyl-terminal hydrolase 64E (EC 3.1.2.15)| (Ubiquitin thioesterase 64E) (Ubiquitin-specific-processing protease 64E) (Deubiquitinating enzyme 64E) Length = 1556 Score = 58.2 bits (139), Expect = 3e-08 Identities = 29/78 (37%), Positives = 43/78 (55%) Frame = -2 Query: 739 SITSCLKNFSSTETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRFKYIEQLGR 560 SI L+ F ETL+ +++ C+KC +A K + K P+IL +HLKRF + Q Sbjct: 548 SIEEALRAFVQPETLDGNNQYLCEKCKKKCDAHKGLHFKSFPYILTLHLKRFDFDYQTMH 607 Query: 559 YKKLSYRVVFPMELKMGS 506 KL+ RV FP L + + Sbjct: 608 RIKLNDRVTFPQTLNLNT 625 Score = 47.4 bits (111), Expect = 5e-05 Identities = 26/75 (34%), Positives = 41/75 (54%), Gaps = 8/75 (10%) Frame = -2 Query: 481 YSLFAVVVHVGSGPNHGHYVSLVKS--HNHWLFFDDENVEMVEESTLQTFFGS------S 326 Y LFA+++H GS GHY + +K +N W F+D+NV + + +Q FG S Sbjct: 704 YELFAIMIHSGSASG-GHYYAYIKDFDNNEWFCFNDQNVTSITQEDIQRSFGGPNGSYYS 762 Query: 325 HEYSGNTDHGYILFY 281 Y+ +T + Y+L Y Sbjct: 763 SAYTSST-NAYMLMY 776
>UBP49_MOUSE (Q6P9L4) Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15)| (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49) Length = 685 Score = 57.8 bits (138), Expect = 4e-08 Identities = 46/150 (30%), Positives = 70/150 (46%), Gaps = 23/150 (15%) Frame = -2 Query: 736 ITSCLKNFSSTETLNAEDKFFCDKCCS-----------LQEAQKRMKIKKAPHILVIHLK 590 +T L F+ TE L + CD+C S L EA+K++ I + P +L +HLK Sbjct: 493 LTEMLAKFTETEALEGRI-YACDQCNSKRRKSNPKPLVLSEARKQLMIYRLPQVLRLHLK 551 Query: 589 RFKYIEQLGRYKKLSYRVVFPMELKMG--------STSDDVDTEYSLFAVVVHVGSGPNH 434 RF++ + R +K+ V+F L M S+ D Y L AVV+H G G Sbjct: 552 RFRWSGRNHR-EKIGVHVIFDQVLTMEPYCCRDMLSSLDKETFAYDLSAVVMHHGKGFGS 610 Query: 433 GHYVSLV--KSHNHWLFFDDENVEM--VEE 356 GHY + W+ +D +++ VEE Sbjct: 611 GHYTAYCYNTEGGFWVHCNDSKLDVCSVEE 640
>UBP40_HUMAN (Q9NVE5) Ubiquitin carboxyl-terminal hydrolase 40 (EC 3.1.2.15)| (Ubiquitin thioesterase 40) (Ubiquitin-specific-processing protease 40) (Deubiquitinating enzyme 40) Length = 1235 Score = 57.4 bits (137), Expect = 5e-08 Identities = 42/148 (28%), Positives = 72/148 (48%), Gaps = 10/148 (6%) Frame = -2 Query: 754 IEQNSSITSCLKN-FSSTETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRFKY 578 ++ S + L N + E + ++ + C C L +A K K++K P L + L RF + Sbjct: 192 VKNVSGLEDALWNMYVEEEVFDCDNLYHCGTCDRLVKAAKSAKLRKLPPFLTVSLLRFNF 251 Query: 577 -IEQLGRYKKLSYRVVFPMELKMG-----STSDDVDTEYSLFAVVVHVGSGPNHGHYVSL 416 + RYK+ S FP+ + + S DD++ Y LF+V++H G G GHY Sbjct: 252 DFVKCERYKETSC-YTFPLRINLKPFCEQSELDDLEYIYDLFSVIIHKG-GCYGGHYHVY 309 Query: 415 VKSHNH---WLFFDDENVEMVEESTLQT 341 +K +H W F ++++ V LQ+ Sbjct: 310 IKDVDHLGNWQFQEEKSKPDVNLKDLQS 337
>UBP32_HUMAN (Q8NFA0) Ubiquitin carboxyl-terminal hydrolase 32 (EC 3.1.2.15)| (Ubiquitin thioesterase 32) (Ubiquitin-specific-processing protease 32) (Deubiquitinating enzyme 32) (NY-REN-60 antigen) Length = 1604 Score = 56.6 bits (135), Expect = 8e-08 Identities = 28/73 (38%), Positives = 45/73 (61%) Frame = -2 Query: 739 SITSCLKNFSSTETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRFKYIEQLGR 560 ++ SCL+ F+S E L + ++C KC + A K++ + + P IL+IHLKRF+++ GR Sbjct: 1234 NLDSCLRAFTSEEELGENEMYYCSKCKTHCLATKKLDLWRLPPILIIHLKRFQFVN--GR 1291 Query: 559 YKKLSYRVVFPME 521 + K V FP E Sbjct: 1292 WIKSQKIVKFPRE 1304 Score = 32.7 bits (73), Expect = 1.3 Identities = 21/69 (30%), Positives = 33/69 (47%), Gaps = 1/69 (1%) Frame = -2 Query: 481 YSLFAVVVHVGSGPNHGHYVSLVKSHN-HWLFFDDENVEMVEESTLQTFFGSSHEYSGNT 305 Y+L+A+ H G GHYV+ K+ N W ++D + + + + +T Sbjct: 1510 YNLYAISCHSGI-LGGGHYVTYAKNPNCKWYCYNDSSCKELHPDEI------------DT 1556 Query: 304 DHGYILFYE 278 D YILFYE Sbjct: 1557 DSAYILFYE 1565
>UBP3_YEAST (Q01477) Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.1.2.15)| (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3) (Deubiquitinating enzyme 3) Length = 912 Score = 55.1 bits (131), Expect = 2e-07 Identities = 47/181 (25%), Positives = 75/181 (41%), Gaps = 26/181 (14%) Frame = -2 Query: 742 SSITSCLKNFSSTETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRFKYIEQL- 566 + + + K FS E L + D EA+K+ I K P +L+I KRF +I + Sbjct: 738 NDLETAFKKFSEYELLPFKSSSGNDV-----EAKKQTFIDKLPQVLLIQFKRFSFINNVN 792 Query: 565 ------------GRYKKLSYRVVFPMELKM-----------GSTSDDVDTEYSLFAVVVH 455 GR +K+ ++ + EL + +TS D Y L V+ H Sbjct: 793 KDNAMTNYNAYNGRIEKIRKKIKYGHELIIPEESMSSITLKNNTSGIDDRRYKLTGVIYH 852 Query: 454 VGSGPNHGHYVSLV--KSHNHWLFFDDENVEMVEESTLQTFFGSSHEYSGNTDHGYILFY 281 G + GHY + V HN W DD N+ +E+ + E + ++ YIL Y Sbjct: 853 HGVSSDGGHYTADVYHSEHNKWYRIDDVNITELEDDDVL----KGGEEASDSRTAYILMY 908 Query: 280 E 278 + Sbjct: 909 Q 909
>UBP15_YEAST (P50101) Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.1.2.15)| (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Deubiquitinating enzyme 15) Length = 1230 Score = 54.3 bits (129), Expect = 4e-07 Identities = 42/159 (26%), Positives = 75/159 (47%), Gaps = 17/159 (10%) Frame = -2 Query: 757 DIEQNSSITSCLKNFSSTETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRFKY 578 +++ ++ N+ E +N E+++ LQ+AQK + + P +L + LKRF+Y Sbjct: 344 NVKNFKNLQESFDNYIEMELMNGENQYAAQDY-GLQDAQKGVIFESFPPVLHLQLKRFEY 402 Query: 577 IEQLGRYKKLSYRVVFPMELKMGSTSD------DVDTE--------YSLFAVVVHVGSGP 440 + K++ + FP + + D +D+E Y+L V+VH G Sbjct: 403 DFNYDQMVKVNDKYEFPETIDLSPFVDKDVLKKTLDSENKDKNPYVYNLHGVLVHSGD-I 461 Query: 439 NHGHYVSLVKS--HNHWLFFDDENV-EMVEESTLQTFFG 332 + GHY +L+K + W FDDE V + ++ Q FG Sbjct: 462 STGHYYTLIKPGVEDQWYRFDDERVWRVTKKQVFQENFG 500
>UBP44_HUMAN (Q9H0E7) Ubiquitin carboxyl-terminal hydrolase 44 (EC 3.1.2.15)| (Ubiquitin thioesterase 44) (Ubiquitin-specific-processing protease 44) (Deubiquitinating enzyme 44) Length = 712 Score = 53.9 bits (128), Expect = 5e-07 Identities = 45/145 (31%), Positives = 65/145 (44%), Gaps = 21/145 (14%) Frame = -2 Query: 736 ITSCLKNFSSTETLNAEDKFFCDKCCS-----------LQEAQKRMKIKKAPHILVIHLK 590 +T L F+ TE L + + CD+C S L EAQK++ I P +L +HLK Sbjct: 517 VTEMLAKFTETEALEGKI-YVCDQCNSKRRRFSSKPVVLTEAQKQLMICHLPQVLRLHLK 575 Query: 589 RFKYIEQLGRYKKLSYRVVFPMELKM-----GSTSDDVDTE---YSLFAVVVHVGSGPNH 434 RF++ + R +K+ V F L M T + E Y L AVV+H G G Sbjct: 576 RFRWSGRNNR-EKIGVHVGFEEILNMEPYCCRETLKSLRPECFIYDLSAVVMHHGKGFGS 634 Query: 433 GHYVSLV--KSHNHWLFFDDENVEM 365 GHY + W+ +D + M Sbjct: 635 GHYTAYCYNSEGGFWVHCNDSKLSM 659
>UBP7_YEAST (P40453) Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.1.2.15)| (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7) (Deubiquitinating enzyme 7) Length = 1071 Score = 53.1 bits (126), Expect = 9e-07 Identities = 45/130 (34%), Positives = 61/130 (46%), Gaps = 9/130 (6%) Frame = -2 Query: 640 KRMKIKKAPHILVIHLKRFKYIEQLGRYKKLSYRVVFPMELKMGSTSDDVDTEYSLFAVV 461 K + P ILVIHL RF Y KK + V +P+ L + ++D +Y LF VV Sbjct: 950 KTINFVTLPKILVIHLSRFYY----DLTKKNNTVVTYPLILNIILKNNDT-MKYKLFGVV 1004 Query: 460 VHVGSGPNHGHYVSLVK---SHN------HWLFFDDENVEMVEESTLQTFFGSSHEYSGN 308 H G+ + GHY SLV HN W +FDDE V+ + GS + Sbjct: 1005 NHTGTLIS-GHYTSLVNKDLEHNVNIGRSKWYYFDDEVVKADRK------HGSDKNLKIS 1057 Query: 307 TDHGYILFYE 278 + Y+LFYE Sbjct: 1058 SSDVYVLFYE 1067
>UBP40_MOUSE (Q8BWR4) Ubiquitin carboxyl-terminal hydrolase 40 (EC 3.1.2.15)| (Ubiquitin thioesterase 40) (Ubiquitin-specific-processing protease 40) (Deubiquitinating enzyme 40) (Fragment) Length = 1140 Score = 52.8 bits (125), Expect = 1e-06 Identities = 35/108 (32%), Positives = 54/108 (50%), Gaps = 6/108 (5%) Frame = -2 Query: 703 ETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRFKY-IEQLGRYKKLSYRVVFP 527 E + ++ + C C L +A K K++K P L I L RF + + RYK S FP Sbjct: 210 EIFDYDNLYHCGTCDRLVKAAKSAKLRKLPPFLTISLLRFNFDFVKCERYKDTSC-YTFP 268 Query: 526 MELKMG-----STSDDVDTEYSLFAVVVHVGSGPNHGHYVSLVKSHNH 398 + + + S DD++ Y LF+V++H G G GHY +K +H Sbjct: 269 LRINLKPFCEQSELDDMEYMYDLFSVIIHKG-GCYGGHYHVYIKDVDH 315
>UBP47_HUMAN (Q96K76) Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15)| (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47) Length = 1375 Score = 52.4 bits (124), Expect = 2e-06 Identities = 30/89 (33%), Positives = 49/89 (55%) Frame = -2 Query: 742 SSITSCLKNFSSTETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRFKYIEQLG 563 +S+ L F E L+ +++FC++C +A+K ++ P++L + LKRF + Sbjct: 341 ASVEEALHAFIQPEILDGPNQYFCERCKKKCDARKGLRFLHFPYLLTLQLKRFDFDYTTM 400 Query: 562 RYKKLSYRVVFPMELKMGSTSDDVDTEYS 476 KL+ R+ FP EL M ST DV+ E S Sbjct: 401 HRIKLNDRMTFPEELDM-STFIDVEDEKS 428
>UBP16_HUMAN (Q9Y5T5) Ubiquitin carboxyl-terminal hydrolase 16 (EC 3.1.2.15)| (Ubiquitin thioesterase 16) (Ubiquitin-specific-processing protease 16) (Deubiquitinating enzyme 16) (Ubiquitin-processing protease UBP-M) Length = 823 Score = 51.2 bits (121), Expect = 3e-06 Identities = 52/193 (26%), Positives = 78/193 (40%), Gaps = 39/193 (20%) Frame = -2 Query: 739 SITSCLKNFSSTETLNAEDKFFCDKCCSLQ-----------------EAQKRMKIKKAPH 611 SI CL F+ E L +K C+ C Q A+K+M I AP Sbjct: 632 SIQHCLYQFTRNEKLRDANKLLCEVCTRRQCNGPKANIKGERKHVYTNAKKQMLISLAPP 691 Query: 610 ILVIHLKRFKYIEQLG-RYKKLSYRVVFPMELKMGS---------TSDDVDTEYSLFAVV 461 +L +HLKRF +Q G +K++ + FP L + ++ YSL+ VV Sbjct: 692 VLTLHLKRF---QQAGFNLRKVNKHIKFPEILDLAPFCTLKCKNVAEENTRVLYSLYGVV 748 Query: 460 VHVGSGPNHGHYVSLVKSH------NHWLFFDDENVEMVEESTLQTF-FGSSHEYSGNT- 305 H G+ GHY + K+ ++ + D + ES Q F +H + T Sbjct: 749 EHSGT-MRSGHYTAYAKARTANSHLSNLVLHGDIPQDFEMESKGQWFHISDTHVQAVPTT 807 Query: 304 ----DHGYILFYE 278 Y+LFYE Sbjct: 808 KVLNSQAYLLFYE 820
>UBP6_HUMAN (P35125) Ubiquitin carboxyl-terminal hydrolase 6 (EC 3.1.2.15)| (Ubiquitin thioesterase 6) (Ubiquitin-specific-processing protease 6) (Deubiquitinating enzyme 6) (Proto-oncogene TRE-2) Length = 1406 Score = 49.7 bits (117), Expect = 1e-05 Identities = 20/55 (36%), Positives = 36/55 (65%) Frame = -2 Query: 739 SITSCLKNFSSTETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRFKYI 575 ++ SCL+ F+S E L + ++C KC + A K++ + + P L+IHLKRF+++ Sbjct: 1032 NLDSCLRAFTSEEELGESEMYYCSKCKTHCLATKKLDLWRLPPFLIIHLKRFQFV 1086 Score = 34.7 bits (78), Expect = 0.33 Identities = 23/71 (32%), Positives = 35/71 (49%), Gaps = 3/71 (4%) Frame = -2 Query: 481 YSLFAVVVHVG--SGPNHGHYVSLVKSHN-HWLFFDDENVEMVEESTLQTFFGSSHEYSG 311 Y+L+A+ H G SG GHY++ K+ N W ++D + E + + Sbjct: 1312 YNLYAISCHSGILSG---GHYITYAKNPNCKWYCYNDSSCEELHPDEI------------ 1356 Query: 310 NTDHGYILFYE 278 +TD YILFYE Sbjct: 1357 DTDSAYILFYE 1367
>UBP11_YEAST (P36026) Ubiquitin carboxyl-terminal hydrolase 11 (EC 3.1.2.15)| (Ubiquitin thioesterase 11) (Ubiquitin-specific-processing protease 11) (Deubiquitinating enzyme 11) Length = 717 Score = 48.9 bits (115), Expect = 2e-05 Identities = 41/122 (33%), Positives = 55/122 (45%), Gaps = 9/122 (7%) Frame = -2 Query: 616 PHILVIHLKRFKYIEQLGRYKKLSYRVVFPMELKMGSTSDDVDTEYSLFAVVVHVGSGPN 437 P ILVIHL RF Y ++Y ++ + LK G Y L+ V H G+ N Sbjct: 593 PPILVIHLSRFYYDLTKKNSTVITYPLILNIILKNGKV-----IRYKLYGTVNHSGNLIN 647 Query: 436 HGHYVSLV---KSH------NHWLFFDDENVEMVEESTLQTFFGSSHEYSGNTDHGYILF 284 GHY S+V KSH W+ FDD+ ++ F E S +D Y+LF Sbjct: 648 -GHYTSVVNKEKSHEIGLNRQVWVTFDDDYIQQ-HRKDRNNFEAGKTEMS--SDEVYVLF 703 Query: 283 YE 278 YE Sbjct: 704 YE 705
>UBP1_ARATH (Q9FPT5) Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.1.2.15)| (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1) (Deubiquitinating enzyme 1) (AtUBP1) Length = 1083 Score = 48.9 bits (115), Expect = 2e-05 Identities = 31/86 (36%), Positives = 49/86 (56%), Gaps = 5/86 (5%) Frame = -2 Query: 652 QEAQKRMKIKKAPHILVIHLKRFKYIEQLGRYKKLSYRVVFPMELKMGS-----TSDDVD 488 ++A+K++ I KAP +L IHLKRF + GR KLS V F + + S++ + Sbjct: 952 RDARKKVLINKAPPVLTIHLKRFSQ-DARGRVSKLSGHVDFQEFIDLSKYMDTRCSEEDE 1010 Query: 487 TEYSLFAVVVHVGSGPNHGHYVSLVK 410 Y L +V H+G+ + GHYVS ++ Sbjct: 1011 PVYRLAGLVEHLGA-MSRGHYVSYIR 1035
>UBP6_YEAST (P43593) Ubiquitin carboxyl-terminal hydrolase 6 (EC 3.1.2.15)| (Ubiquitin thioesterase 6) (Ubiquitin-specific-processing protease 6) (Deubiquitinating enzyme 6) Length = 499 Score = 48.1 bits (113), Expect = 3e-05 Identities = 27/92 (29%), Positives = 44/92 (47%), Gaps = 3/92 (3%) Frame = -2 Query: 544 YRVVFPMELKMGSTSDDVDTEYSLFAVVVHVGSGPNHGHYVSLVK---SHNHWLFFDDEN 374 Y+ FP L+ G V Y+L V+ H G+ GHY + ++ N W F+D+ Sbjct: 412 YKKHFPPNLEKGENPSCV---YNLIGVITHQGANSESGHYQAFIRDELDENKWYKFNDDK 468 Query: 373 VEMVEESTLQTFFGSSHEYSGNTDHGYILFYE 278 V +VE+ +++ G G +D IL Y+ Sbjct: 469 VSVVEKEKIESLAG-----GGESDSALILMYK 495
>UBP14_RABIT (P40826) Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.1.2.15)| (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) (Deubiquitinating enzyme 14) Length = 492 Score = 46.2 bits (108), Expect = 1e-04 Identities = 28/81 (34%), Positives = 40/81 (49%), Gaps = 5/81 (6%) Frame = -2 Query: 508 STSDDVDTE----YSLFAVVVHVGSGPNHGHYVSLVK-SHNHWLFFDDENVEMVEESTLQ 344 S +DD+ + Y L AV+ H G + GHYVS VK H+ W+ FDD+ V +V + Sbjct: 403 SFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKHDEWIKFDDDKVSIVTPEDIL 462 Query: 343 TFFGSSHEYSGNTDHGYILFY 281 G G+ Y+L Y Sbjct: 463 RLSG-----GGDWHIAYVLLY 478
>UBP2_ARATH (Q8W4N3) Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.1.2.15)| (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) (Deubiquitinating enzyme 2) (AtUBP2) Length = 961 Score = 45.8 bits (107), Expect = 1e-04 Identities = 53/190 (27%), Positives = 81/190 (42%), Gaps = 31/190 (16%) Frame = -2 Query: 754 IEQNSSITSCLKNFSS-------------TETLNAEDKFF-CDKCCSLQ-EAQKRMKIKK 620 ++Q+ + TSC+K+ SS +E+ +D+ +K +++ +A K++ I K Sbjct: 781 VKQDPNDTSCVKDHSSDGRKAARIHSADESESKGTQDEDEDSEKVITVKRDATKKVLINK 840 Query: 619 APHILVIHLKRFKYIEQLGRYKKLSYRVVFPMELKM-----GSTSDDVDTEYSLFAVVVH 455 AP +L IHLKRF + GR KL+ V F + + S + Y L +V H Sbjct: 841 APPVLTIHLKRFSQ-DLRGRLSKLNGHVAFKEVIDLRQYMDSRCSGEDPPVYRLAGLVEH 899 Query: 454 VGSGPNHGHYVSLVK----------SHNHWLFFDDENVEMVE-ESTLQTFFGSSHEYSGN 308 G+ GHYV+ V+ S W D V V E L + Sbjct: 900 SGT-MRGGHYVAYVRGGQRVKETDSSSTAWYNVSDAYVRQVSLEKVLHS----------- 947 Query: 307 TDHGYILFYE 278 YILFYE Sbjct: 948 --EAYILFYE 955
>UBPA_DICDI (P54201) Ubiquitin carboxyl-terminal hydrolase A (EC 3.1.2.15)| (Ubiquitin thioesterase A) (Ubiquitin-specific-processing protease A) (Deubiquitinating enzyme A) Length = 837 Score = 45.8 bits (107), Expect = 1e-04 Identities = 41/179 (22%), Positives = 71/179 (39%), Gaps = 19/179 (10%) Frame = -2 Query: 757 DIEQNSSITSCLKNFSSTETLNAEDKFFC---------------DKCCSLQEAQKRMKIK 623 DIEQ T + N ++ + N+ DK F D L + ++ Sbjct: 676 DIEQ----TPVINNNNNNNSSNSNDKLFVFNSQDVDNIIGMGFTDSQAKLALKNTKGNLE 731 Query: 622 KAPHILVIHLKRFKYIEQLGRYKKLSYRVVFPMELKMGSTS----DDVDTEYSLFAVVVH 455 +A L H+ +++L S + P + +TS D +Y L + H Sbjct: 732 RAADWLFSHIDN---LDELVAKDNASTSSINPSLIPQSTTSLQPVSDGVGKYELLGFISH 788 Query: 454 VGSGPNHGHYVSLVKSHNHWLFFDDENVEMVEESTLQTFFGSSHEYSGNTDHGYILFYE 278 +G+ GHYV +K +N W+ F+D +V++ E+ + GYI FY+ Sbjct: 789 LGNNVTCGHYVCHIKKNNRWIKFNDRHVQLSEQPPKEL--------------GYIYFYK 833
>UBP37_HUMAN (Q86T82) Ubiquitin carboxyl-terminal hydrolase 37 (EC 3.1.2.15)| (Ubiquitin thioesterase 37) (Ubiquitin-specific-processing protease 37) (Deubiquitinating enzyme 37) Length = 979 Score = 45.1 bits (105), Expect = 2e-04 Identities = 36/136 (26%), Positives = 59/136 (43%), Gaps = 12/136 (8%) Frame = -2 Query: 652 QEAQKRMKIKKAPHILVIHLKRFK--YIEQLGRYKKLSYRVVFPME--------LKMGST 503 QEA ++ + + L+ F +++ LG + VF ME LK + Sbjct: 822 QEAWEQKEDDDLKRATELSLQEFNNSFVDALGSDEDSGNEDVFDMEYTEAEAEELKRNAE 881 Query: 502 SDDVDTEYSLFAVVVHVGSGPNHGHYVSLVK--SHNHWLFFDDENVEMVEESTLQTFFGS 329 + ++ Y L +VV H+GS + GHY+S V W ++D V ++E+ +Q Sbjct: 882 TGNLPHSYRLISVVSHIGSTSSSGHYISDVYDIKKQAWFTYNDLEVSKIQEAAVQ----- 936 Query: 328 SHEYSGNTDHGYILFY 281 S GYI FY Sbjct: 937 ----SDRDRSGYIFFY 948 Score = 38.9 bits (89), Expect = 0.017 Identities = 25/81 (30%), Positives = 39/81 (48%), Gaps = 3/81 (3%) Frame = -2 Query: 739 SITSCLKNFSSTETLNAEDKFFCDKC---CSLQEAQKRMKIKKAPHILVIHLKRFKYIEQ 569 SI L F E L ++ C+KC C+L R K + P +L++HLKR+ + Sbjct: 520 SIQDSLDLFFRAEEL----EYSCEKCGGKCALV----RHKFNRLPRVLILHLKRYSFNVA 571 Query: 568 LGRYKKLSYRVVFPMELKMGS 506 L K+ +V+ P L + S Sbjct: 572 LSLNNKIGQQVIIPRYLTLSS 592
>UBP29_MOUSE (Q9ES63) Ubiquitin carboxyl-terminal hydrolase 29 (EC 3.1.2.15)| (Ubiquitin thioesterase 29) (Ubiquitin-specific-processing protease 29) (Deubiquitinating enzyme 29) Length = 869 Score = 43.9 bits (102), Expect = 5e-04 Identities = 29/81 (35%), Positives = 36/81 (44%), Gaps = 2/81 (2%) Frame = -2 Query: 517 KMGSTSDDVDTEYSLFAVVVHVGSGPNHGHYVSLVKSHNH--WLFFDDENVEMVEESTLQ 344 K G DD+ Y L +VV H GS PN GHYVS V WL + D V + ++Q Sbjct: 753 KDGEMGDDLQN-YRLVSVVSHFGSSPNSGHYVSDVYDFQKQAWLLYSDVQVFESSDPSIQ 811 Query: 343 TFFGSSHEYSGNTDHGYILFY 281 + GYI FY Sbjct: 812 ---------ENRLNSGYIFFY 823
>UBP14_CAEEL (Q17361) Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.1.2.15)| (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) (Deubiquitinating enzyme 14) Length = 489 Score = 43.5 bits (101), Expect = 7e-04 Identities = 23/70 (32%), Positives = 34/70 (48%), Gaps = 2/70 (2%) Frame = -2 Query: 481 YSLFAVVVHVGSGPNHGHYVSLVKS--HNHWLFFDDENVEMVEESTLQTFFGSSHEYSGN 308 Y L ++ H G GHYV+ ++S W FDDE+V +V+E + G G+ Sbjct: 392 YDLKGIITHKGRSSQDGHYVAWMRSSEDGKWRLFDDEHVTVVDEEAILKTSG-----GGD 446 Query: 307 TDHGYILFYE 278 Y+L YE Sbjct: 447 WHSAYVLLYE 456
>UBP14_PANTR (P60051) Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.1.2.15)| (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) (Deubiquitinating enzyme 14) Length = 492 Score = 43.1 bits (100), Expect = 0.001 Identities = 27/81 (33%), Positives = 39/81 (48%), Gaps = 5/81 (6%) Frame = -2 Query: 508 STSDDVDTE----YSLFAVVVHVGSGPNHGHYVSLVK-SHNHWLFFDDENVEMVEESTLQ 344 S +DD+ + Y L AV+ H G + GHYVS VK + W+ FDD+ V +V + Sbjct: 404 SFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDIL 463 Query: 343 TFFGSSHEYSGNTDHGYILFY 281 G G+ Y+L Y Sbjct: 464 RLSG-----GGDWHIAYVLLY 479
>UBP14_HUMAN (P54578) Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.1.2.15)| (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) (Deubiquitinating enzyme 14) Length = 493 Score = 43.1 bits (100), Expect = 0.001 Identities = 27/81 (33%), Positives = 39/81 (48%), Gaps = 5/81 (6%) Frame = -2 Query: 508 STSDDVDTE----YSLFAVVVHVGSGPNHGHYVSLVK-SHNHWLFFDDENVEMVEESTLQ 344 S +DD+ + Y L AV+ H G + GHYVS VK + W+ FDD+ V +V + Sbjct: 404 SFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDIL 463 Query: 343 TFFGSSHEYSGNTDHGYILFY 281 G G+ Y+L Y Sbjct: 464 RLSG-----GGDWHIAYVLLY 479
>UBP14_MOUSE (Q9JMA1) Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.1.2.15)| (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) (Deubiquitinating enzyme 14) Length = 492 Score = 42.7 bits (99), Expect = 0.001 Identities = 29/90 (32%), Positives = 43/90 (47%), Gaps = 7/90 (7%) Frame = -2 Query: 529 PMELKMG--STSDDVDTE----YSLFAVVVHVGSGPNHGHYVSLV-KSHNHWLFFDDENV 371 P E+K S +DD+ + Y L AV+ H G + GHYVS V + + W+ FDD+ V Sbjct: 394 PKEIKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVRRKQDEWIKFDDDKV 453 Query: 370 EMVEESTLQTFFGSSHEYSGNTDHGYILFY 281 +V + G G+ Y+L Y Sbjct: 454 SIVTPEDILRLSG-----GGDWHIAYVLLY 478
>UBP6_SCHPO (Q92353) Ubiquitin carboxyl-terminal hydrolase 6 (EC 3.1.2.15)| (Ubiquitin thiolesterase 6) (Ubiquitin-specific processing protease 6) (Deubiquitinating enzyme 6) Length = 467 Score = 42.7 bits (99), Expect = 0.001 Identities = 22/71 (30%), Positives = 35/71 (49%), Gaps = 3/71 (4%) Frame = -2 Query: 481 YSLFAVVVHVGSGPNHGHYVSLVKSHNH---WLFFDDENVEMVEESTLQTFFGSSHEYSG 311 Y L V+ H G+ + GHY + +++ N+ W F+D V +V ++T G G Sbjct: 397 YDLVGVLSHAGASASSGHYQAWIRNSNNRAEWFRFNDAKVSIVPAEKIETLDG-----GG 451 Query: 310 NTDHGYILFYE 278 D YIL Y+ Sbjct: 452 EADSAYILLYK 462
>UBP29_HUMAN (Q9HBJ7) Ubiquitin carboxyl-terminal hydrolase 29 (EC 3.1.2.15)| (Ubiquitin thioesterase 29) (Ubiquitin-specific-processing protease 29) (Deubiquitinating enzyme 29) Length = 922 Score = 42.4 bits (98), Expect = 0.002 Identities = 24/69 (34%), Positives = 32/69 (46%), Gaps = 2/69 (2%) Frame = -2 Query: 481 YSLFAVVVHVGSGPNHGHYVSLVKSHNH--WLFFDDENVEMVEESTLQTFFGSSHEYSGN 308 Y L +VV H+GS PN GHY+S V W ++D V + E+ +Q Sbjct: 823 YRLISVVSHIGSSPNSGHYISDVYDFQKQAWFTYNDLCVSEISETKMQ---------EAR 873 Query: 307 TDHGYILFY 281 GYI FY Sbjct: 874 LHSGYIFFY 882
>UBP5_MOUSE (P56399) Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15)| (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T) Length = 858 Score = 41.2 bits (95), Expect = 0.004 Identities = 23/79 (29%), Positives = 35/79 (44%) Frame = -2 Query: 514 MGSTSDDVDTEYSLFAVVVHVGSGPNHGHYVSLVKSHNHWLFFDDENVEMVEESTLQTFF 335 +G D +Y LFA + H+G+ GHYV +K W+ ++D+ V E+ Sbjct: 790 VGPKVRDGPGKYQLFAFISHMGTSTMCGHYVCHIKKEGRWVIYNDQKVCASEKPP----- 844 Query: 334 GSSHEYSGNTDHGYILFYE 278 D GYI FY+ Sbjct: 845 ---------KDLGYIYFYQ 854
>UBP5_HUMAN (P45974) Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15)| (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T) Length = 858 Score = 41.2 bits (95), Expect = 0.004 Identities = 23/79 (29%), Positives = 35/79 (44%) Frame = -2 Query: 514 MGSTSDDVDTEYSLFAVVVHVGSGPNHGHYVSLVKSHNHWLFFDDENVEMVEESTLQTFF 335 +G D +Y LFA + H+G+ GHYV +K W+ ++D+ V E+ Sbjct: 790 VGPKVRDGPGKYQLFAFISHMGTSTMCGHYVCHIKKEGRWVIYNDQKVCASEKPP----- 844 Query: 334 GSSHEYSGNTDHGYILFYE 278 D GYI FY+ Sbjct: 845 ---------KDLGYIYFYQ 854
>UBP26_MOUSE (Q99MX1) Ubiquitin carboxyl-terminal hydrolase 26 (EC 3.1.2.15)| (Ubiquitin thioesterase 26) (Ubiquitin-specific-processing protease 26) (Deubiquitinating enzyme 26) Length = 835 Score = 40.0 bits (92), Expect = 0.008 Identities = 20/72 (27%), Positives = 32/72 (44%), Gaps = 2/72 (2%) Frame = -2 Query: 490 DTEYSLFAVVVHVGSGPNHGHYV--SLVKSHNHWLFFDDENVEMVEESTLQTFFGSSHEY 317 D Y L ++ H+G+ PN GHY+ + W + D +V +E + Y Sbjct: 751 DNVYRLVNIINHIGNSPNGGHYINDAFDFKRQSWFTYSDLHVTRTQEDFV---------Y 801 Query: 316 SGNTDHGYILFY 281 G + GY+ FY Sbjct: 802 RGRSSTGYVFFY 813
>UBP14_SCHPO (Q11119) Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.1.2.15)| (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) (Deubiquitinating enzyme 14) (UBA-domain-containing protein 2) Length = 775 Score = 39.7 bits (91), Expect = 0.010 Identities = 21/56 (37%), Positives = 31/56 (55%), Gaps = 5/56 (8%) Frame = -2 Query: 514 MGS-TSDDVDTEYSLFAVVVHVGSGPNHGHYVSLVKSH----NHWLFFDDENVEMV 362 MGS S +V Y+L A++ H GS + GHYV+ ++ W+ F+DE V V Sbjct: 701 MGSWESTNVPVNYNLKAIISHKGSSAHAGHYVAFIRKEIDGKQQWVLFNDEKVLQV 756
>UBP2_KLULA (O42726) Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.1.2.15)| (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) (Deubiquitinating enzyme 2) Length = 1220 Score = 39.3 bits (90), Expect = 0.013 Identities = 25/70 (35%), Positives = 35/70 (50%), Gaps = 3/70 (4%) Frame = -2 Query: 481 YSLFAVVVHVGSGPNHGHYVSLVKSHNH---WLFFDDENVEMVEESTLQTFFGSSHEYSG 311 YSLFAV +H G ++GHY +K H W ++D++V V +S + F G Sbjct: 1137 YSLFAVFIHRGEA-SYGHYWVYIKDHTKNGIWRKYNDDSVTEVPQSEVFNF------TEG 1189 Query: 310 NTDHGYILFY 281 NT Y L Y Sbjct: 1190 NTATPYFLVY 1199
>UBP14_ARATH (Q8L6Y1) Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.1.2.15)| (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) (Deubiquitinating enzyme 14) (AtUBP14) (TITAN-6 protein) Length = 797 Score = 39.3 bits (90), Expect = 0.013 Identities = 14/38 (36%), Positives = 24/38 (63%) Frame = -2 Query: 484 EYSLFAVVVHVGSGPNHGHYVSLVKSHNHWLFFDDENV 371 +Y LF +V H+G+ + GHYV+ + W+ F+D+ V Sbjct: 740 KYKLFGIVSHMGTSVHCGHYVAHILKEGRWVIFNDDKV 777
>UBP1_YEAST (P25037) Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.1.2.15)| (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1) (Deubiquitinating enzyme 1) Length = 809 Score = 38.9 bits (89), Expect = 0.017 Identities = 25/77 (32%), Positives = 38/77 (49%) Frame = -2 Query: 508 STSDDVDTEYSLFAVVVHVGSGPNHGHYVSLVKSHNHWLFFDDENVEMVEESTLQTFFGS 329 ST YSL +V+VH G+ N+GHY++ K W DE V +V+E+ + Sbjct: 672 STVPATPLTYSLRSVIVHYGTH-NYGHYIAFRKYRGCWWRISDETVYVVDEAEVL----- 725 Query: 328 SHEYSGNTDHGYILFYE 278 +T ++LFYE Sbjct: 726 ------STPGVFMLFYE 736
>UBP13_HUMAN (Q92995) Ubiquitin carboxyl-terminal hydrolase 13 (EC 3.1.2.15)| (Ubiquitin thioesterase 13) (Ubiquitin-specific-processing protease 13) (Deubiquitinating enzyme 13) (Isopeptidase T-3) (ISOT-3) Length = 863 Score = 38.5 bits (88), Expect = 0.023 Identities = 15/47 (31%), Positives = 23/47 (48%) Frame = -2 Query: 511 GSTSDDVDTEYSLFAVVVHVGSGPNHGHYVSLVKSHNHWLFFDDENV 371 G D Y LFA + H+G+ GHY+ +K W+ ++D V Sbjct: 796 GPRVKDGSGTYELFAFISHMGTSTMSGHYICHIKKEGRWVIYNDHKV 842
>UBP26_HUMAN (Q9BXU7) Ubiquitin carboxyl-terminal hydrolase 26 (EC 3.1.2.15)| (Ubiquitin thioesterase 26) (Ubiquitin-specific-processing protease 26) (Deubiquitinating enzyme 26) Length = 913 Score = 32.7 bits (73), Expect = 1.3 Identities = 22/75 (29%), Positives = 30/75 (40%), Gaps = 2/75 (2%) Frame = -2 Query: 499 DDVDTEYSLFAVVVHVGSGPNHGHYVSLVKSHNH--WLFFDDENVEMVEESTLQTFFGSS 326 D D Y L +VV H+G GHY+ W +DD V ++E+ +Q Sbjct: 818 DKGDHTYRLISVVSHLGKTLKSGHYICDAYDFEKQIWFTYDDMRVLGIQEAQMQ------ 871 Query: 325 HEYSGNTDHGYILFY 281 GYI FY Sbjct: 872 ---EDRRCTGYIFFY 883 Score = 30.0 bits (66), Expect = 8.1 Identities = 29/112 (25%), Positives = 46/112 (41%), Gaps = 12/112 (10%) Frame = -2 Query: 742 SSITSCLKNFSSTETLNAEDKFFCDKCCSLQEAQKRMKIKKAPHILVIHLKRFKYIEQLG 563 SSI S F E L ++ C KC + + + P IL++HLKR+ + + Sbjct: 477 SSIQSTFDLFFGAEEL----EYKCAKC-EHKTSVGVHSFSRLPRILIVHLKRYS-LNEFC 530 Query: 562 RYKKLSYRVVFPMELKMGS------------TSDDVDTEYSLFAVVVHVGSG 443 KK V+ LK+ S + D T++ L V+ + SG Sbjct: 531 ALKKNDQEVIISKYLKVSSHCNEGTRPPLPLSEDGEITDFQLLKVIRKMTSG 582
>UBP14_YEAST (P38237) Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.1.2.15)| (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) (Deubiquitinating enzyme 14) (Glucose-induced degradation protein 6) Length = 803 Score = 32.3 bits (72), Expect = 1.6 Identities = 21/71 (29%), Positives = 34/71 (47%), Gaps = 4/71 (5%) Frame = -2 Query: 481 YSLFAVVVHVGSGPNHGHYV----SLVKSHNHWLFFDDENVEMVEESTLQTFFGSSHEYS 314 Y+L AV+ H G+ + GHYV LV W+ ++DE ++V +++ Sbjct: 742 YALTAVICHKGNSVHSGHYVVFIRKLVADKWKWVLYNDE--KLVAADSIEDM-------- 791 Query: 313 GNTDHGYILFY 281 +GYI FY Sbjct: 792 --KKNGYIYFY 800
>RNZ_BACFR (Q64XI2) Ribonuclease Z (EC 3.1.26.11) (RNase Z) (tRNase Z) (tRNA 3| endonuclease) Length = 304 Score = 31.2 bits (69), Expect = 3.6 Identities = 13/46 (28%), Positives = 26/46 (56%), Gaps = 3/46 (6%) Frame = -2 Query: 721 KNFSSTETLNAEDKFF---CDKCCSLQEAQKRMKIKKAPHILVIHL 593 ++F++++ +N DK F C + +Q + R+K + HI + HL Sbjct: 19 RHFATSQVVNLRDKLFMIDCGEGAQMQLRKSRLKFSRLNHIFISHL 64
>RNZ_BACFN (Q5LGN7) Ribonuclease Z (EC 3.1.26.11) (RNase Z) (tRNase Z) (tRNA 3| endonuclease) Length = 304 Score = 31.2 bits (69), Expect = 3.6 Identities = 13/46 (28%), Positives = 26/46 (56%), Gaps = 3/46 (6%) Frame = -2 Query: 721 KNFSSTETLNAEDKFF---CDKCCSLQEAQKRMKIKKAPHILVIHL 593 ++F++++ +N DK F C + +Q + R+K + HI + HL Sbjct: 19 RHFATSQVVNLRDKLFMIDCGEGAQMQLRKSRLKFSRLNHIFISHL 64 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 103,382,431 Number of Sequences: 219361 Number of extensions: 2057047 Number of successful extensions: 5514 Number of sequences better than 10.0: 102 Number of HSP's better than 10.0 without gapping: 5288 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5462 length of database: 80,573,946 effective HSP length: 110 effective length of database: 56,444,236 effective search space used: 8015081512 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
