ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | rbags33b24 |
|---|---|
| Clone Library Name | barley_pub |
>CP51_WHEAT (P93596) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Obtusifoliol 14-alpha demethylase) (Fragment) Length = 453 Score = 252 bits (644), Expect = 5e-67 Identities = 120/125 (96%), Positives = 121/125 (96%) Frame = -2 Query: 562 VXTREGKEFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISF 383 V TREGKEFDI KGH VATS AFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISF Sbjct: 329 VTTREGKEFDIPKGHIVATSPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISF 388 Query: 382 GGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFPENDWNAMVVGIKGEVMVNYKRRK 203 GGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFPENDWNAMVVGIKGEVMVNYKRRK Sbjct: 389 GGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFPENDWNAMVVGIKGEVMVNYKRRK 448 Query: 202 LVVDN 188 L+VDN Sbjct: 449 LIVDN 453
>CP51_SORBI (P93846) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Obtusifoliol 14-alpha demethylase) Length = 492 Score = 243 bits (620), Expect = 3e-64 Identities = 114/125 (91%), Positives = 118/125 (94%) Frame = -2 Query: 562 VXTREGKEFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISF 383 V T+EGKE+DI KGH VATS +FANRLPHI+KNPDSYDPDRF GREEDK AGAFSYISF Sbjct: 368 VTTKEGKEYDIPKGHIVATSPSFANRLPHIYKNPDSYDPDRFGPGREEDKAAGAFSYISF 427 Query: 382 GGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFPENDWNAMVVGIKGEVMVNYKRRK 203 GGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFPENDWNAMVVGIKGEVMVNYKRRK Sbjct: 428 GGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFPENDWNAMVVGIKGEVMVNYKRRK 487 Query: 202 LVVDN 188 LVVDN Sbjct: 488 LVVDN 492
>CP51_MYCVN (Q5IZM4) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (P450-14DM) Length = 452 Score = 100 bits (250), Expect = 2e-21 Identities = 53/114 (46%), Positives = 73/114 (64%), Gaps = 3/114 (2%) Frame = -2 Query: 538 FDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCL 359 + I KG VA S A +NR+P F NPD +DPDR+ R+ED + +++I FG G+H C+ Sbjct: 338 YPIHKGQMVAASPAISNRIPEDFPNPDDFDPDRYEKPRQEDLI-NRWTWIPFGAGKHRCV 396 Query: 358 GEPFAYLQIKAIWTHLLRNFEFELVSPFPE---NDWNAMVVGIKGEVMVNYKRR 206 G FA +QIKAI++ LLR +EFE+ P PE ND + MVV + V Y+RR Sbjct: 397 GAAFAQMQIKAIFSVLLREYEFEMAQP-PESYQNDHSKMVVQLARPAKVRYRRR 449
>CP51_MYCTU (P0A512) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (P450-14DM) Length = 451 Score = 87.8 bits (216), Expect = 2e-17 Identities = 49/112 (43%), Positives = 69/112 (61%), Gaps = 3/112 (2%) Frame = -2 Query: 532 IXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGE 353 I +G VA S A +NR+P F +P + P R+ R+ED + +++I FG GRH C+G Sbjct: 339 IHEGDLVAASPAISNRIPEDFPDPHDFVPARYEQPRQED-LLNRWTWIPFGAGRHRCVGA 397 Query: 352 PFAYLQIKAIWTHLLRNFEFELVSPFPE---NDWNAMVVGIKGEVMVNYKRR 206 FA +QIKAI++ LLR +EFE+ P PE ND + MVV + V Y+RR Sbjct: 398 AFAIMQIKAIFSVLLREYEFEMAQP-PESYRNDHSKMVVQLAQPACVRYRRR 448
>CP51_MYCBO (P0A513) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (P450-14DM) Length = 451 Score = 87.8 bits (216), Expect = 2e-17 Identities = 49/112 (43%), Positives = 69/112 (61%), Gaps = 3/112 (2%) Frame = -2 Query: 532 IXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGE 353 I +G VA S A +NR+P F +P + P R+ R+ED + +++I FG GRH C+G Sbjct: 339 IHEGDLVAASPAISNRIPEDFPDPHDFVPARYEQPRQED-LLNRWTWIPFGAGRHRCVGA 397 Query: 352 PFAYLQIKAIWTHLLRNFEFELVSPFPE---NDWNAMVVGIKGEVMVNYKRR 206 FA +QIKAI++ LLR +EFE+ P PE ND + MVV + V Y+RR Sbjct: 398 AFAIMQIKAIFSVLLREYEFEMAQP-PESYRNDHSKMVVQLAQPACVRYRRR 448
>CP51A_RAT (Q64654) Cytochrome P450 51A1 (EC 1.14.13.70) (CYPLI) (P450LI)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (LDM) (P450-14DM) Length = 503 Score = 75.5 bits (184), Expect = 1e-13 Identities = 42/113 (37%), Positives = 66/113 (58%), Gaps = 2/113 (1%) Frame = -2 Query: 538 FDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGA-FSYISFGGGRHGC 362 + I GH V S RL + ++PDR+ +++ +G F+Y+ FG GRH C Sbjct: 393 YTIPPGHQVCVSPTVNQRLKDSWVERLDFNPDRYL---QDNPASGEKFAYVPFGAGRHRC 449 Query: 361 LGEPFAYLQIKAIWTHLLRNFEFELVSP-FPENDWNAMVVGIKGEVMVNYKRR 206 +GE FAY+QIK IW+ +LR +EF+L++ FP ++ M+ + V + YKRR Sbjct: 450 IGENFAYVQIKTIWSTMLRLYEFDLINGYFPSVNYTTMIHTPENPV-IRYKRR 501
>CP51A_PONPY (Q5RE72) Cytochrome P450 51A1 (EC 1.14.13.70) (CYPLI) (P450LI)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (LDM) (P450-14DM) (P45014DM) Length = 503 Score = 74.7 bits (182), Expect = 2e-13 Identities = 42/113 (37%), Positives = 65/113 (57%), Gaps = 2/113 (1%) Frame = -2 Query: 538 FDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGA-FSYISFGGGRHGC 362 + I GH V S RL + ++PDR+ +++ +G F+Y+ FG GRH C Sbjct: 393 YTIPPGHQVCVSPTVNQRLKDSWVERLDFNPDRYL---QDNPASGEKFAYVPFGAGRHRC 449 Query: 361 LGEPFAYLQIKAIWTHLLRNFEFELVSP-FPENDWNAMVVGIKGEVMVNYKRR 206 +GE FAY+QIK IW+ +LR +EF+L+ FP ++ M+ + V + YKRR Sbjct: 450 IGENFAYVQIKTIWSTMLRLYEFDLIDGYFPTVNYTTMIHTPENPV-IRYKRR 501
>CP51A_PIG (O46420) Cytochrome P450 51A1 (EC 1.14.13.70) (CYPLI) (P450LI)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (LDM) (P450-14DM) Length = 503 Score = 74.7 bits (182), Expect = 2e-13 Identities = 42/113 (37%), Positives = 65/113 (57%), Gaps = 2/113 (1%) Frame = -2 Query: 538 FDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGA-FSYISFGGGRHGC 362 + I GH V S RL + ++PDR+ +++ +G F+Y+ FG GRH C Sbjct: 393 YTIPPGHQVCVSPTVNQRLKDSWVERLDFNPDRYL---QDNPASGEKFAYVPFGAGRHRC 449 Query: 361 LGEPFAYLQIKAIWTHLLRNFEFELVSP-FPENDWNAMVVGIKGEVMVNYKRR 206 +GE FAY+QIK IW+ +LR +EF+L+ FP ++ M+ + V + YKRR Sbjct: 450 IGENFAYVQIKTIWSTMLRLYEFDLIDGYFPTVNYTTMIHTPENPV-IRYKRR 501
>CP51A_HUMAN (Q16850) Cytochrome P450 51A1 (EC 1.14.13.70) (CYPLI) (P450LI)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (LDM) (P450-14DM) (P45014DM) Length = 503 Score = 74.7 bits (182), Expect = 2e-13 Identities = 42/113 (37%), Positives = 65/113 (57%), Gaps = 2/113 (1%) Frame = -2 Query: 538 FDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGA-FSYISFGGGRHGC 362 + I GH V S RL + ++PDR+ +++ +G F+Y+ FG GRH C Sbjct: 393 YTIPPGHQVCVSPTVNQRLKDSWVERLDFNPDRYL---QDNPASGEKFAYVPFGAGRHRC 449 Query: 361 LGEPFAYLQIKAIWTHLLRNFEFELVSP-FPENDWNAMVVGIKGEVMVNYKRR 206 +GE FAY+QIK IW+ +LR +EF+L+ FP ++ M+ + V + YKRR Sbjct: 450 IGENFAYVQIKTIWSTMLRLYEFDLIDGYFPTVNYTTMIHTPENPV-IRYKRR 501
>CP51A_BOVIN (Q4PJW3) Cytochrome P450 51A1 (EC 1.14.13.70) (CYPLI) (P450LI)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (LDM) (P450-14DM) (P45014DM) Length = 502 Score = 74.7 bits (182), Expect = 2e-13 Identities = 42/113 (37%), Positives = 64/113 (56%), Gaps = 2/113 (1%) Frame = -2 Query: 538 FDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGA-FSYISFGGGRHGC 362 + I GH V S RL + ++PDR+ E+ +G F+Y+ FG GRH C Sbjct: 392 YTIPPGHQVCVSPTVNQRLKDSWVERLDFNPDRYL---EDSPASGEKFAYVPFGAGRHRC 448 Query: 361 LGEPFAYLQIKAIWTHLLRNFEFELVSP-FPENDWNAMVVGIKGEVMVNYKRR 206 +GE FAY+QIK IW+ +LR +EF+L+ FP ++ M + + ++ YKRR Sbjct: 449 IGENFAYVQIKTIWSTMLRLYEFDLIDGYFPTVNYTTM-IHTPEKPIIRYKRR 500
>CP51_USTMA (P49602) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (P450-14DM) Length = 561 Score = 69.3 bits (168), Expect = 7e-12 Identities = 43/113 (38%), Positives = 59/113 (52%), Gaps = 17/113 (15%) Frame = -2 Query: 532 IXKGHXVATSXAFANRLPHIFKNPDSYDPDRF-----AAGRE---EDKVAGAFS------ 395 I KGH + + + P I+K+ D +DP R+ AA + EDK F Sbjct: 428 IPKGHYIMAAPGVSQVDPQIWKSSDQFDPHRWLDATTAAAMQDSGEDKQDFGFGMISTGA 487 Query: 394 ---YISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFPENDWNAMVV 245 Y+ FG GRH C+GE FAYLQI I +R F++ L S FP+ D+ +MVV Sbjct: 488 NSPYLPFGAGRHRCIGEQFAYLQIGVILATFVRIFKWHLDSKFPDPDYQSMVV 540
>CP136_MYCTU (P95099) Putative cytochrome P450 136 (EC 1.14.-.-)| Length = 492 Score = 65.5 bits (158), Expect = 1e-10 Identities = 39/104 (37%), Positives = 56/104 (53%), Gaps = 2/104 (1%) Frame = -2 Query: 526 KGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPF 347 KG V +RLP I+ +P ++DP+RF R E K +++ FGGG H C+G F Sbjct: 386 KGTNVIAYPGMNHRLPEIWTDPLTFDPERFTEPRNEHK-RHRYAFTPFGGGVHKCIGMVF 444 Query: 346 AYLQIKAIWTHLLRNFEFELVSP--FPENDWNAMVVGIKGEVMV 221 L+IK I LLR + EL P P D++AM + + G +V Sbjct: 445 DQLEIKTILHRLLRRYRLELSRPDYQPRWDYSAMPIPMDGMPIV 488
>CP51_CANAL (P10613) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (P450-14DM) Length = 528 Score = 63.2 bits (152), Expect = 5e-10 Identities = 39/115 (33%), Positives = 56/115 (48%), Gaps = 19/115 (16%) Frame = -2 Query: 532 IXKGHXVATSXAFANRLPHIFKNPDSYDPDR------------FAAGREEDKVAGAFS-- 395 + KGH V S +A+ F NP+ +DP R F + E D G S Sbjct: 396 VPKGHYVLVSPGYAHTSERYFDNPEDFDPTRWDTAAAKANSVSFNSSDEVDYGFGKVSKG 455 Query: 394 ----YISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVS-PFPENDWNAMVV 245 Y+ FGGGRH C+GE FAY+Q+ I T + N + + P+ D+++MVV Sbjct: 456 VSSPYLPFGGGRHRCIGEQFAYVQLGTILTTFVYNLRWTIDGYKVPDPDYSSMVV 510
>CP51_CANTR (P14263) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (P450-14DM) Length = 528 Score = 62.4 bits (150), Expect = 9e-10 Identities = 38/117 (32%), Positives = 59/117 (50%), Gaps = 19/117 (16%) Frame = -2 Query: 541 EFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAG---------REEDKVAGAFS-- 395 ++ I KGH V S +A+ F++P+ ++P R+ + ED V F Sbjct: 393 KYVIPKGHYVLVSAGYAHTSDRWFEHPEHFNPRRWESDDTKASAVSFNSEDTVDYGFGKI 452 Query: 394 -------YISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL-VSPFPENDWNAMV 248 Y+ FGGGRH C+GE FAY+Q+ I T + NF++ L P+ D+ +MV Sbjct: 453 SKGVSSPYLPFGGGRHRCIGEQFAYVQLGTILTTYIYNFKWRLNGDKVPDVDYQSMV 509
>CP26B_HUMAN (Q9NR63) Cytochrome P450 26B1 (EC 1.14.-.-) (P450 26A2) (P450| retinoic acid-inactivating 2) (P450RAI-2) (Retinoic-acid metabolizing cytochrome) Length = 512 Score = 60.1 bits (144), Expect = 4e-09 Identities = 34/86 (39%), Positives = 45/86 (52%) Frame = -2 Query: 538 FDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCL 359 F I KG V S + +FK+ + +DPDRF+ R EDK G F Y+ FGGG CL Sbjct: 384 FQIPKGWSVMYSIRDTHDTAPVFKDVNVFDPDRFSQARSEDK-DGRFHYLPFGGGVRTCL 442 Query: 358 GEPFAYLQIKAIWTHLLRNFEFELVS 281 G+ A L +K + L FEL + Sbjct: 443 GKHLAKLFLKVLAVELASTSRFELAT 468
>CP9F2_DROME (Q9VG82) Probable cytochrome P450 9f2 (EC 1.14.-.-) (CYPIXF2)| Length = 516 Score = 58.5 bits (140), Expect = 1e-08 Identities = 28/86 (32%), Positives = 49/86 (56%) Frame = -2 Query: 550 EGKEFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGR 371 +G++ ++ KG + +R P F+NP +DP+RF+ +E F+Y FG G+ Sbjct: 400 DGQKVEVKKGDVIWLPTCGFHRDPKYFENPMKFDPERFSDENKES--IQPFTYFPFGLGQ 457 Query: 370 HGCLGEPFAYLQIKAIWTHLLRNFEF 293 C+G FA L+ KA+ +LL+++ F Sbjct: 458 RNCIGSRFALLEAKAVIYYLLKDYRF 483
>CP26C_HUMAN (Q6V0L0) Cytochrome P450 26C1 (EC 1.14.-.-)| Length = 522 Score = 58.5 bits (140), Expect = 1e-08 Identities = 32/92 (34%), Positives = 51/92 (55%), Gaps = 3/92 (3%) Frame = -2 Query: 538 FDIXKGHXVATSXAFANRLPHIFKNP-DSYDPDRFAAGREEDKVAGA-FSYISFGGGRHG 365 + I KG V S + ++++P + +DP+RF A RE+ + A + F YI FGGG Sbjct: 399 YQIPKGWSVMYSIRDTHETAAVYRSPPEGFDPERFGAAREDSRGASSRFHYIPFGGGARS 458 Query: 364 CLGEPFAYLQIKAIWTHLLRNFEFELVSP-FP 272 CLG+ A ++ + L+R +EL +P FP Sbjct: 459 CLGQELAQAVLQLLAVELVRTARWELATPAFP 490
>CP6K1_BLAGE (Q964R0) Cytochrome P450 6k1 (EC 1.14.-.-) (CYPVIK1)| Length = 524 Score = 58.2 bits (139), Expect = 2e-08 Identities = 25/65 (38%), Positives = 38/65 (58%) Frame = -2 Query: 490 NRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHL 311 +R P + NP+ YDP+RF+ E + A++Y+ FG G H C+G F Y+ +K H+ Sbjct: 424 HRDPQYYPNPERYDPERFS--EENKRQRKAYTYLPFGEGPHNCIGLRFGYMAVKTALVHM 481 Query: 310 LRNFE 296 L FE Sbjct: 482 LAEFE 486
>CP26A_MOUSE (O55127) Cytochrome P450 26A1 (EC 1.14.-.-) (Retinoic| acid-metabolizing cytochrome) (P450RAI) (Retinoic acid 4-hydroxylase) Length = 497 Score = 58.2 bits (139), Expect = 2e-08 Identities = 33/95 (34%), Positives = 50/95 (52%) Frame = -2 Query: 556 TREGKEFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGG 377 T E + I KG V S + + IF N + ++PDRF ED A FS+I FGG Sbjct: 380 TFELNGYQIPKGWNVIYSICDTHDVADIFTNKEEFNPDRFIVPHPED--ASRFSFIPFGG 437 Query: 376 GRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFP 272 G C+G+ FA + +K L R+ +++L++ P Sbjct: 438 GLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPP 472
>CP26A_HUMAN (O43174) Cytochrome P450 26A1 (EC 1.14.-.-) (Retinoic| acid-metabolizing cytochrome) (P450 retinoic acid-inactivating 1) (P450RAI) (hP450RAI) (Retinoic acid 4-hydroxylase) Length = 497 Score = 58.2 bits (139), Expect = 2e-08 Identities = 33/95 (34%), Positives = 50/95 (52%) Frame = -2 Query: 556 TREGKEFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGG 377 T E + I KG V S + + IF N + ++PDRF ED A FS+I FGG Sbjct: 380 TFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPED--ASRFSFIPFGG 437 Query: 376 GRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFP 272 G C+G+ FA + +K L R+ +++L++ P Sbjct: 438 GLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPP 472
>CP4CU_BLAGE (Q964T1) Cytochrome P450 4c21 (EC 1.14.14.1) (CYPIVC21)| Length = 501 Score = 57.8 bits (138), Expect = 2e-08 Identities = 29/86 (33%), Positives = 47/86 (54%) Frame = -2 Query: 538 FDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCL 359 + I G + S F +R P IF NP ++PD F R ++ ++YI F G C+ Sbjct: 391 YTIPAGTNIDFSVPFIHRNPEIFPNPRCFNPDNFLPDRVVNR--HPYAYIPFSAGPRNCI 448 Query: 358 GEPFAYLQIKAIWTHLLRNFEFELVS 281 G+ FA L+ K + ++LLR++ F V+ Sbjct: 449 GQRFALLEEKVVLSYLLRHYRFRTVN 474
>CP26A_CHICK (Q9PUB4) Cytochrome P450 26A1 (EC 1.14.-.-) (Retinoic acid| degrading enzyme CYP26) Length = 492 Score = 57.4 bits (137), Expect = 3e-08 Identities = 34/120 (28%), Positives = 60/120 (50%), Gaps = 10/120 (8%) Frame = -2 Query: 556 TREGKEFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGG 377 T E + I KG V S + + +F + D ++PDRF + ED + FS+I FGG Sbjct: 375 TLELNGYQIPKGWNVIYSICDTHDVADLFTDKDEFNPDRFMSPSPED--SSRFSFIPFGG 432 Query: 376 GRHGCLGEPFAYLQIKAIWTHLLRNFEFELVS----------PFPENDWNAMVVGIKGEV 227 G C+G+ FA + +K L R+ +++L++ +P ++ A +G G++ Sbjct: 433 GLRSCVGKEFAKVLLKIFTVELARSCDWQLLNGPPTMKTGPIVYPVDNLPAKFIGFSGQI 492
>CP26B_BRARE (Q6EIG3) Cytochrome P450 26B1 (EC 1.14.-.-) (Cyp26B1)| (Retinoic-acid metabolizing cytochrome) Length = 511 Score = 57.4 bits (137), Expect = 3e-08 Identities = 31/82 (37%), Positives = 44/82 (53%) Frame = -2 Query: 532 IXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGE 353 + KG V S + +FK+ +++DPDRF+ R ED+ G F Y+ FGGG CLG+ Sbjct: 385 VPKGWSVMYSIRDTHDTSAVFKDVEAFDPDRFSPERSEDR-EGRFHYLPFGGGVRSCLGK 443 Query: 352 PFAYLQIKAIWTHLLRNFEFEL 287 A L +K + L FEL Sbjct: 444 QLATLFLKLLAVELAGGSRFEL 465
>CP4D1_DROSI (O16805) Cytochrome P450 4d1 (EC 1.14.-.-) (CYPIVD1)| Length = 512 Score = 57.4 bits (137), Expect = 3e-08 Identities = 29/88 (32%), Positives = 47/88 (53%) Frame = -2 Query: 532 IXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGE 353 I G + S + R +F P+S+ P+RF +K+ ++YI F G C+G+ Sbjct: 401 IPAGTNIGISPLYLGRREELFSEPNSFKPERFDVVTTAEKL-NPYAYIPFSAGPRNCIGQ 459 Query: 352 PFAYLQIKAIWTHLLRNFEFELVSPFPE 269 FA L+IKAI ++LR++E + V E Sbjct: 460 KFAMLEIKAIVANVLRHYEVDFVGDSSE 487
>CP4D1_DROME (P33269) Cytochrome P450 4d1 (EC 1.14.-.-) (CYPIVD1)| Length = 512 Score = 57.4 bits (137), Expect = 3e-08 Identities = 29/88 (32%), Positives = 47/88 (53%) Frame = -2 Query: 532 IXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGE 353 I G + S + R +F P+S+ P+RF +K+ ++YI F G C+G+ Sbjct: 401 IPAGTNIGISPLYLGRREELFSEPNSFKPERFDVVTTAEKL-NPYAYIPFSAGPRNCIGQ 459 Query: 352 PFAYLQIKAIWTHLLRNFEFELVSPFPE 269 FA L+IKAI ++LR++E + V E Sbjct: 460 KFAMLEIKAIVANVLRHYEVDFVGDSSE 487
>CP312_DROME (Q9VVN6) Probable cytochrome P450 312a1 (EC 1.14.-.-) (CYPCCCXIIA1)| Length = 510 Score = 57.0 bits (136), Expect = 4e-08 Identities = 32/84 (38%), Positives = 43/84 (51%) Frame = -2 Query: 541 EFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGC 362 +F I KG V S + R F +P + PDR+A G E A F I F G C Sbjct: 398 DFFIPKGSDVIISPIYMGRCKDFFPDPMVFKPDRWAIGAEPKIEATTF--IPFMAGARSC 455 Query: 361 LGEPFAYLQIKAIWTHLLRNFEFE 290 +G+ +A + +K + HLLRNF FE Sbjct: 456 MGQRYAMVMLKMVLAHLLRNFLFE 479
>CP51_CUNEL (Q9UVC3) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (P450-14DM) Length = 512 Score = 57.0 bits (136), Expect = 4e-08 Identities = 38/135 (28%), Positives = 61/135 (45%), Gaps = 19/135 (14%) Frame = -2 Query: 550 EGKEFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREE------------DKVA 407 E +I KG+ + + P F P +Y+P R+ + D Sbjct: 378 EKNGMEIPKGNFICAAPGVTQVDPTYFNEPTTYNPYRWIEKTDPVHQLEQGDDANIDYGF 437 Query: 406 GAFS------YISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL-VSPFPENDWNAMV 248 GA ++ FG GRH C+GE F YLQ+K + + +R F+F+L P++D+ +MV Sbjct: 438 GAVGISSKSPFLPFGAGRHRCIGEQFGYLQLKTVISTFIRTFDFDLDGKSVPKSDYTSMV 497 Query: 247 VGIKGEVMVNYKRRK 203 V + V Y R+ Sbjct: 498 VVPEHTAKVRYTWRE 512
>CP51_ASHGO (Q759W0) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (P450-14DM) Length = 529 Score = 56.6 bits (135), Expect = 5e-08 Identities = 37/126 (29%), Positives = 60/126 (47%), Gaps = 17/126 (13%) Frame = -2 Query: 532 IXKGHXVATSXAFANRLPHIFKNPDSYDPDRF--------AAGREEDKVAGAFS------ 395 I K H V S F + F N ++P R+ + G + D GA S Sbjct: 398 IPKDHYVLASPGFCHLSEEYFPNAKEFNPHRWDNDAASSVSTGEKVDYGFGAISKGVSSP 457 Query: 394 YISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL---VSPFPENDWNAMVVGIKGEVM 224 Y+ FGGGRH C+GE FAY+Q+ I++ ++R+ ++ + P D+ +MV Sbjct: 458 YLPFGGGRHRCIGEGFAYMQLGTIFSVVVRSMKWHFPADMKGVPNPDFTSMVTLPSEPCR 517 Query: 223 VNYKRR 206 + ++RR Sbjct: 518 IAWERR 523
>CP51_SCHPO (Q09736) Probable cytochrome P450 51 (EC 1.14.13.70) (CYPLI)| (P450-LIA1) (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (P450-14DM) Length = 495 Score = 56.6 bits (135), Expect = 5e-08 Identities = 31/102 (30%), Positives = 50/102 (49%), Gaps = 13/102 (12%) Frame = -2 Query: 472 FKNPDSYDPDRFAAGREEDKVA-------------GAFSYISFGGGRHGCLGEPFAYLQI 332 F + +DP R+ ED+ A A Y+ FG GRH C+GE FAY+ + Sbjct: 393 FTHATDFDPKRWNDRVNEDENAEQIDYGYGLVTKGAASPYLPFGAGRHRCIGEQFAYMHL 452 Query: 331 KAIWTHLLRNFEFELVSPFPENDWNAMVVGIKGEVMVNYKRR 206 I + + ++ + L+ P D+++MV G V + +KRR Sbjct: 453 STIISKFVHDYTWTLIGKVPNVDYSSMVALPLGPVKIAWKRR 494
>C6A13_DROME (Q9V4U9) Probable cytochrome P450 6a13 (EC 1.14.-.-) (CYPVIA13)| Length = 493 Score = 56.2 bits (134), Expect = 6e-08 Identities = 26/63 (41%), Positives = 38/63 (60%) Frame = -2 Query: 481 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 302 P ++ +P+ +DP RF EE K F+Y+ FG G C+GE F LQ+K +LLR+ Sbjct: 398 PELYPDPEKFDPSRFEP--EEIKARHPFAYLPFGEGPRNCIGERFGKLQVKVGLVYLLRD 455 Query: 301 FEF 293 F+F Sbjct: 456 FKF 458
>C4D10_DROMT (O18596) Cytochrome P450 4d10 (EC 1.14.-.-) (CYPIVD10)| Length = 513 Score = 55.8 bits (133), Expect = 8e-08 Identities = 34/111 (30%), Positives = 55/111 (49%), Gaps = 2/111 (1%) Frame = -2 Query: 532 IXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGE 353 I G + S F R I P+++ P+RF +K+ +YI F G C+G+ Sbjct: 402 IPAGTNIGISPLFLGRSEDISSEPNTFKPERFDVVTSAEKL-NPHAYIPFSAGPRNCIGQ 460 Query: 352 PFAYLQIKAIWTHLLRNFEFELVSPFPEND--WNAMVVGIKGEVMVNYKRR 206 FA L+IKAI ++LR++E E V E+ +++ K +M K+R Sbjct: 461 KFAMLEIKAIAANVLRHYEIEFVGNAEESPVLIAELILRTKDPLMFKLKKR 511
>CP6G2_DROME (Q9V675) Probable cytochrome P450 6g2 (EC 1.14.-.-) (CYPVIG2)| Length = 519 Score = 55.8 bits (133), Expect = 8e-08 Identities = 39/120 (32%), Positives = 55/120 (45%), Gaps = 3/120 (2%) Frame = -2 Query: 544 KEFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHG 365 K+F + KG V + P F P + P+RF+ E K+ ++Y+ FG G HG Sbjct: 402 KKFVVPKGMPVYIPCYALHMDPQYFPQPRKFLPERFSP--ENRKLHTPYTYMPFGLGPHG 459 Query: 364 CLGEPFAYLQIKAIWTHLLRNFEFELVSPFPEN---DWNAMVVGIKGEVMVNYKRRKLVV 194 C+GE F YLQ K +LLRN P D A++ KG + + R L V Sbjct: 460 CIGERFGYLQAKVGLVNLLRNHMITTSERTPHRMQLDPKAIITQAKGGIHLRLVRDALGV 519
>CP51_PENIT (Q12664) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Sterol 14-alpha demethylase) (Eburicol 14-alpha-demethylase) (P450-14DM) Length = 515 Score = 55.1 bits (131), Expect = 1e-07 Identities = 35/115 (30%), Positives = 57/115 (49%), Gaps = 16/115 (13%) Frame = -2 Query: 547 GKEFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVA-------GAFS-- 395 G +F + H + +S R F++P +DP R+ + E + + GA S Sbjct: 385 GTDFVVPPSHTLLSSPGVTARDERHFRDPLRWDPHRWESRVEVEDSSDTVDYGYGAVSKG 444 Query: 394 ----YISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEF---ELVSPFPENDWNAM 251 Y+ FG GRH C+GE FAYL ++ I L+R F F E + P+ D++++ Sbjct: 445 TRSPYLPFGAGRHRCIGEKFAYLNLEVIVATLVREFRFFNPEGMEGVPDTDYSSL 499
>CP4D2_DROME (Q27589) Cytochrome P450 4d2 (EC 1.14.-.-) (CYPIVD2)| Length = 501 Score = 54.7 bits (130), Expect = 2e-07 Identities = 28/85 (32%), Positives = 46/85 (54%) Frame = -2 Query: 487 RLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLL 308 R P F++PD + P+RF A + ++YI F G C+G+ FA L++K+ + LL Sbjct: 411 RDPEYFESPDEFRPERFDADVPQ---IHPYAYIPFSAGPRNCIGQKFAMLEMKSTVSKLL 467 Query: 307 RNFEFELVSPFPENDWNAMVVGIKG 233 R+FE + P P + N ++ G Sbjct: 468 RHFELLPLGPEPRHSMNIVLRSANG 492
>THAS_PIG (P47787) Thromboxane-A synthase (EC 5.3.99.5) (TXA synthase) (TXS)| Length = 534 Score = 54.3 bits (129), Expect = 2e-07 Identities = 25/64 (39%), Positives = 37/64 (57%) Frame = -2 Query: 481 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 302 P + +P+++DP+RF A E ++ F+Y+ FG G CLG L+IK H+LR Sbjct: 443 PKHWPHPETFDPERFTA--EAQRLQQPFTYLPFGAGPRSCLGVQLGLLEIKLTLLHILRK 500 Query: 301 FEFE 290 F FE Sbjct: 501 FRFE 504
>CP26A_XENLA (O93323) Cytochrome P450 26A1 (EC 1.14.-.-) (Retinoic acid| degrading enzyme CYP26) (xCYP26) (Retinoic acid-converting enzyme) (RACE) Length = 492 Score = 53.9 bits (128), Expect = 3e-07 Identities = 30/89 (33%), Positives = 46/89 (51%) Frame = -2 Query: 538 FDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCL 359 + I KG V S A + +F + D ++PDRF D + F +I FGGG C+ Sbjct: 381 YQIPKGWNVIYSIADTHGEADLFPDTDKFNPDRFLTPLPRD--SSRFGFIPFGGGVRCCI 438 Query: 358 GEPFAYLQIKAIWTHLLRNFEFELVSPFP 272 G+ FA + +K L RN ++EL++ P Sbjct: 439 GKEFAKILLKVFVVELCRNCDWELLNGSP 467
>CP9E2_BLAGE (Q964T2) Cytochrome P450 9e2 (EC 1.14.-.-) (CYPIXE2)| Length = 533 Score = 53.1 bits (126), Expect = 5e-07 Identities = 24/70 (34%), Positives = 39/70 (55%) Frame = -2 Query: 481 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 302 P + NP+ +DP+RF+ +++ F+Y+ FG G C+G FA ++ K HLL Sbjct: 438 PKYYPNPEKFDPERFSDENKDN--IKPFTYLPFGSGPRNCIGNRFALMESKIALVHLLCR 495 Query: 301 FEFELVSPFP 272 F ++VS P Sbjct: 496 FNLKVVSKTP 505
>C4G15_DROME (Q9VYY4) Cytochrome P450 4g15 (EC 1.14.-.-) (CYPIVG15)| Length = 574 Score = 53.1 bits (126), Expect = 5e-07 Identities = 25/91 (27%), Positives = 50/91 (54%) Frame = -2 Query: 532 IXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGE 353 I +G V + +R P ++ NP+ +DPD F R+ ++ ++++ F G C+G Sbjct: 465 IPRGATVTVATVLLHRNPKVYANPNVFDPDNFLPERQANR--HYYAFVPFSAGPRSCVGR 522 Query: 352 PFAYLQIKAIWTHLLRNFEFELVSPFPENDW 260 +A L++K + + +LRN + + S E+D+ Sbjct: 523 KYAMLKLKILLSTILRN--YRVYSDLTESDF 551
>CP11A_DASAM (Q92045) Cytochrome P450 11A1, mitochondrial precursor (EC| 1.14.15.6) (CYPXIA1) (P450(SCC)) (Cholesterol side-chain cleavage enzyme) (Cholesterol desmolase) (Fragment) Length = 514 Score = 52.4 bits (124), Expect = 9e-07 Identities = 27/85 (31%), Positives = 42/85 (49%) Frame = -2 Query: 544 KEFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHG 365 + + I G V R P IFKNP+ Y+P+R+ G + F ++ FG G Sbjct: 406 QNYHIPAGTLVQLGLYAMGRNPKIFKNPEQYNPERWLKGEDTH-----FRHLGFGFGPRQ 460 Query: 364 CLGEPFAYLQIKAIWTHLLRNFEFE 290 C+G A Q+ + H+L+NF+ E Sbjct: 461 CIGRRIAETQMVLLMIHMLQNFKIE 485
>C4AA1_DROME (Q9V7G5) Probable cytochrome P450 4aa1 (EC 1.14.-.-) (CYPIVAA1)| Length = 514 Score = 52.4 bits (124), Expect = 9e-07 Identities = 27/94 (28%), Positives = 51/94 (54%), Gaps = 5/94 (5%) Frame = -2 Query: 562 VXTREGKEFDIXKGHXVATSXAF-----ANRLPHIFKNPDSYDPDRFAAGREEDKVAGAF 398 + + G+E + K A S F +RL HI+ +P+ + P+RF+ E++ + Sbjct: 385 IARKLGEEVRLAKHTLPAGSNVFICPYATHRLAHIYPDPEKFQPERFSPENSENR--HPY 442 Query: 397 SYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFE 296 +++ F G C+G FA ++IK I + LLR+++ Sbjct: 443 AFLPFSAGPRYCIGNRFAIMEIKTIVSRLLRSYQ 476
>CP4E1_DROME (Q9V4T5) Probable cytochrome P450 4e1 (EC 1.14.-.-) (CYPIVE1)| Length = 531 Score = 52.4 bits (124), Expect = 9e-07 Identities = 22/60 (36%), Positives = 36/60 (60%) Frame = -2 Query: 475 IFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFE 296 +FK+P + P+RF + + G F Y+ F G C+G+ FA L+IK + + ++RNFE Sbjct: 412 VFKDPHKFQPERF-----DREKPGPFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFE 466
>CP4E2_DROME (Q27606) Cytochrome P450 4e2 (EC 1.14.-.-) (CYPIVE2)| Length = 526 Score = 52.0 bits (123), Expect = 1e-06 Identities = 23/60 (38%), Positives = 36/60 (60%) Frame = -2 Query: 475 IFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFE 296 +FK+P + P+RF E + G F Y+ F G C+G+ FA L+IK + + ++RNFE Sbjct: 412 VFKDPHKFRPERF-----ELEKPGPFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFE 466
>CP120_SYNY3 (Q59990) Putative cytochrome P450 120 (EC 1.14.-.-)| Length = 444 Score = 52.0 bits (123), Expect = 1e-06 Identities = 26/85 (30%), Positives = 46/85 (54%) Frame = -2 Query: 538 FDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCL 359 F KG V+ + + P ++ +P+ +DP+RF F+++ FGGG CL Sbjct: 334 FHFPKGWLVSYQISQTHADPDLYPDPEKFDPERFTPDGSATHNP-PFAHVPFGGGLRECL 392 Query: 358 GEPFAYLQIKAIWTHLLRNFEFELV 284 G+ FA L++K T L++ F++ L+ Sbjct: 393 GKEFARLEMKLFATRLIQQFDWTLL 417
>CP51_MIMIV (Q5UQI3) Probable cytochrome P450 51 (EC 1.14.13.70) (CYPLI)| (P450-LIA1) (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (P450-14DM) Length = 709 Score = 51.6 bits (122), Expect = 2e-06 Identities = 25/60 (41%), Positives = 38/60 (63%) Frame = -2 Query: 475 IFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFE 296 ++ NP+SYDP RF A R E K +G +++G G H C G+ FA ++KA +++ NFE Sbjct: 390 VYANPNSYDPVRFMAPRNEPKDSG--HVMNWGKGVHECPGKQFAIYEVKAAIAYIVTNFE 447
>CP138_MYCTU (P63717) Putative cytochrome P450 138 (EC 1.14.-.-)| Length = 441 Score = 51.6 bits (122), Expect = 2e-06 Identities = 25/84 (29%), Positives = 44/84 (52%) Frame = -2 Query: 541 EFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGC 362 E+ I +G+ + + A + P +F PD +DP R+ + F++I FGGG C Sbjct: 334 EWVIPRGYSIIINIAQIHGDPDVFPQPDRFDPQRYIGSKPSP-----FAWIPFGGGTRRC 388 Query: 361 LGEPFAYLQIKAIWTHLLRNFEFE 290 +G FA +++ + +LR+F E Sbjct: 389 VGAAFANMEMDVVLRTVLRHFTLE 412
>CP138_MYCBO (P63718) Putative cytochrome P450 138 (EC 1.14.-.-)| Length = 441 Score = 51.6 bits (122), Expect = 2e-06 Identities = 25/84 (29%), Positives = 44/84 (52%) Frame = -2 Query: 541 EFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGC 362 E+ I +G+ + + A + P +F PD +DP R+ + F++I FGGG C Sbjct: 334 EWVIPRGYSIIINIAQIHGDPDVFPQPDRFDPQRYIGSKPSP-----FAWIPFGGGTRRC 388 Query: 361 LGEPFAYLQIKAIWTHLLRNFEFE 290 +G FA +++ + +LR+F E Sbjct: 389 VGAAFANMEMDVVLRTVLRHFTLE 412
>CP46A_MOUSE (Q9WVK8) Cytochrome p450 46A1 (EC 1.14.13.98) (Cholesterol| 24-hydroxylase) (CH24H) Length = 500 Score = 51.6 bits (122), Expect = 2e-06 Identities = 23/68 (33%), Positives = 39/68 (57%) Frame = -2 Query: 487 RLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLL 308 R+ F++P +++PDRF G + + F+Y F G C+G+ FA +++K + LL Sbjct: 400 RMDTYFEDPLTFNPDRFGPGAPKPR----FTYFPFSLGHRSCIGQQFAQMEVKVVMAKLL 455 Query: 307 RNFEFELV 284 + EF LV Sbjct: 456 QRIEFRLV 463
>CP46A_HUMAN (Q9Y6A2) Cytochrome p450 46A1 (EC 1.14.13.98) (Cholesterol| 24-hydroxylase) (CH24H) Length = 500 Score = 51.6 bits (122), Expect = 2e-06 Identities = 23/68 (33%), Positives = 39/68 (57%) Frame = -2 Query: 487 RLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLL 308 R+ F++P +++PDRF G + + F+Y F G C+G+ FA +++K + LL Sbjct: 400 RMDTYFEDPLTFNPDRFGPGAPKPR----FTYFPFSLGHRSCIGQQFAQMEVKVVMAKLL 455 Query: 307 RNFEFELV 284 + EF LV Sbjct: 456 QRLEFRLV 463
>CP4S3_DROME (Q9VXY0) Probable cytochrome P450 4s3 (EC 1.14.-.-) (CYPIVS3)| Length = 495 Score = 51.6 bits (122), Expect = 2e-06 Identities = 25/80 (31%), Positives = 42/80 (52%) Frame = -2 Query: 532 IXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGE 353 + KG ++ +R P F +P+ +DPDRF +K F++ +F G C+G+ Sbjct: 383 VPKGASISCLIYMLHRDPKNFPDPERFDPDRFLVN---EKQMHPFAFAAFSAGPRNCIGQ 439 Query: 352 PFAYLQIKAIWTHLLRNFEF 293 FA L++K LLR++ F Sbjct: 440 KFAMLELKTSLAMLLRSYRF 459
>CP6T1_DROME (Q9VRI9) Probable cytochrome P450 6t1 (EC 1.14.-.-) (CYPVIT1)| Length = 529 Score = 51.2 bits (121), Expect = 2e-06 Identities = 28/87 (32%), Positives = 44/87 (50%) Frame = -2 Query: 547 GKEFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRH 368 G F + G V S +R + NP+ +DP+RF+A E+ + +Y+ FG G Sbjct: 413 GSPFKLRAGTPVYISVLGIHRDAQYWPNPEVFDPERFSA--EQRQQHHPMTYLPFGAGPR 470 Query: 367 GCLGEPFAYLQIKAIWTHLLRNFEFEL 287 GC+G L+IK H+L +F E+ Sbjct: 471 GCIGTLLGQLEIKVGLLHILNHFRVEV 497
>CP6B6_HELAM (Q95031) Cytochrome P450 6B6 (EC 1.14.14.1) (CYPVIB6)| Length = 504 Score = 50.8 bits (120), Expect = 3e-06 Identities = 41/123 (33%), Positives = 53/123 (43%), Gaps = 6/123 (4%) Frame = -2 Query: 547 GKEFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRH 368 G + I K V S + P + NP ++PDRF A EE +Y+ FG G+ Sbjct: 386 GTDVVIEKDTIVLISPRGIHYDPKYYDNPKQFNPDRFDA--EEVGKRHPCAYLPFGLGQR 443 Query: 367 GCLGEPFAYLQIKAIWTHLLRNFEFELVSPFPENDWNAMV------VGIKGEVMVNYKRR 206 C+G F LQ T +L F E P D N V +G KG + VN R Sbjct: 444 NCIGMRFGRLQSLLCITKILSKFRIE---PSKNTDRNLQVEPHRGLIGPKGGIRVNVVPR 500 Query: 205 KLV 197 KLV Sbjct: 501 KLV 503
>CP4G1_DROME (Q9V3S0) Cytochrome P450 4g1 (EC 1.14.-.-) (CYPIVG1)| Length = 556 Score = 50.8 bits (120), Expect = 3e-06 Identities = 24/80 (30%), Positives = 42/80 (52%) Frame = -2 Query: 538 FDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCL 359 + + KG V +R P I+ NP +DPD F R ++ +S+I F G C+ Sbjct: 441 YTVPKGTTVIVLQYCVHRRPDIYPNPTKFDPDNFLPERMANR--HYYSFIPFSAGPRSCV 498 Query: 358 GEPFAYLQIKAIWTHLLRNF 299 G +A L++K + + ++RN+ Sbjct: 499 GRKYAMLKLKVLLSTIVRNY 518
>CP4C3_DROME (Q9VA27) Cytochrome P450 4c3 (EC 1.14.-.-) (CYPIVC3)| Length = 535 Score = 50.4 bits (119), Expect = 3e-06 Identities = 26/73 (35%), Positives = 40/73 (54%), Gaps = 4/73 (5%) Frame = -2 Query: 490 NRLPHIFKNPDSYDPDRF----AAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAI 323 +R P +F P+ ++PD F AGR F+YI F G C+G+ FA L+ KA+ Sbjct: 441 HRNPRVFPKPEQFNPDNFLPENCAGRHP------FAYIPFSAGPRNCIGQKFAILEEKAV 494 Query: 322 WTHLLRNFEFELV 284 + +LR ++ E V Sbjct: 495 ISTVLRKYKIEAV 507
>C6A18_DROME (Q9VB31) Probable cytochrome P450 6a18 (EC 1.14.-.-) (CYPVIA18)| Length = 507 Score = 50.4 bits (119), Expect = 3e-06 Identities = 30/111 (27%), Positives = 55/111 (49%), Gaps = 4/111 (3%) Frame = -2 Query: 541 EFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGC 362 +F I G V + + P I+ P+ + P+RF+ EE + +++ FG G C Sbjct: 394 KFVIEAGQSVIIPSSAIHHDPSIYPEPNEFRPERFSP--EESAKRPSVAWLPFGEGPRNC 451 Query: 361 LGEPFAYLQIKAIWTHLLRNFEFELVSPFPE----NDWNAMVVGIKGEVMV 221 +G F +Q + L++NF F S P+ + +A+++GIKG + + Sbjct: 452 IGLRFGQMQARIGLAMLIKNFTFSPCSATPDPLTFDPHSAILLGIKGGIQL 502
>C97B2_SOYBN (O48921) Cytochrome P450 97B2 (EC 1.14.-.-)| Length = 576 Score = 50.4 bits (119), Expect = 3e-06 Identities = 28/104 (26%), Positives = 48/104 (46%), Gaps = 20/104 (19%) Frame = -2 Query: 538 FDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAG--------------- 404 + I G V S +R P+ + PD ++P+RF + +++ G Sbjct: 441 YAIPAGTDVFISVYNLHRSPYFWDRPDDFEPERFLVQNKNEEIEGWAGLDPSRSPGALYP 500 Query: 403 -----AFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL 287 F+++ FGGG C+G+ FA ++ T LL+NF+ EL Sbjct: 501 NEVISDFAFLPFGGGPRKCVGDQFALMESTVALTMLLQNFDVEL 544
>CP4E3_DROME (Q9VL92) Cytochrome P450 4e3 (EC 1.14.-.-) (CYPIVE3)| Length = 526 Score = 50.1 bits (118), Expect = 5e-06 Identities = 29/88 (32%), Positives = 47/88 (53%), Gaps = 5/88 (5%) Frame = -2 Query: 544 KEFDIX-----KGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFG 380 K++DI KG + + IFK+P + P+RF EE+K A F Y+ F Sbjct: 383 KDYDINGSIVPKGTTLNLALILLGYNDRIFKDPHHFRPERF----EEEKPA-PFEYLPFS 437 Query: 379 GGRHGCLGEPFAYLQIKAIWTHLLRNFE 296 G C+G+ FA L++K + + ++R+FE Sbjct: 438 AGPRNCIGQKFALLELKTVISKVVRSFE 465
>CP6B7_HELAM (O61387) Cytochrome P450 6B7 (EC 1.14.14.1) (CYPVIB7)| Length = 504 Score = 50.1 bits (118), Expect = 5e-06 Identities = 40/123 (32%), Positives = 53/123 (43%), Gaps = 6/123 (4%) Frame = -2 Query: 547 GKEFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRH 368 G + I K V S + P + NP ++PDRF A EE +Y+ FG G+ Sbjct: 386 GTDVVIEKDTMVLISPRGIHYDPKYYDNPKQFNPDRFDA--EEVGKRHPCAYLPFGLGQR 443 Query: 367 GCLGEPFAYLQIKAIWTHLLRNFEFELVSPFPENDWNAMV------VGIKGEVMVNYKRR 206 C+G F LQ T +L F E P D N V +G KG + VN R Sbjct: 444 NCIGMRFGRLQSLLCITKILSKFRIE---PSKNTDRNLQVEPRRVTIGPKGGIRVNIVPR 500 Query: 205 KLV 197 K+V Sbjct: 501 KIV 503
>CP9B2_DROME (Q9V4I1) Cytochrome P450 9b2 (EC 1.14.-.-) (CYPIXB2)| Length = 505 Score = 50.1 bits (118), Expect = 5e-06 Identities = 26/85 (30%), Positives = 44/85 (51%) Frame = -2 Query: 544 KEFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHG 365 K FD G + + + F P +DPDRF+ R+ D V ++Y+ FG G Sbjct: 391 KLFDFKVGDRINIPISGLHLDDRYFPEPRKFDPDRFSEERKGDMVP--YTYLPFGVGPRN 448 Query: 364 CLGEPFAYLQIKAIWTHLLRNFEFE 290 C+G +A +Q+K + +LL +++ E Sbjct: 449 CIGNRYALMQVKGMLFNLLLHYKIE 473
>CP132_MYCTU (P77900) Putative cytochrome P450 132 (EC 1.14.-.-)| Length = 461 Score = 50.1 bits (118), Expect = 5e-06 Identities = 31/97 (31%), Positives = 49/97 (50%), Gaps = 5/97 (5%) Frame = -2 Query: 562 VXTREGKEFDIXKGHXVATSXAFANRLPHIFKNPDSY-DPDRFAAGR----EEDKVAGAF 398 + RE + DI GH + + HI +P + DPDRF GR D+ A Sbjct: 340 IIAREAVDDDIIDGHRIRRGTTVVIPIHHIHHDPRWWPDPDRFDPGRFLRCPTDRPRCA- 398 Query: 397 SYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL 287 Y+ FGGGR C+G+ FA +++ + + ++F F+L Sbjct: 399 -YLPFGGGRRICIGQSFALMEMVLMAAIMSQHFTFDL 434
>CP132_MYCBO (P59954) Putative cytochrome P450 132 (EC 1.14.-.-)| Length = 461 Score = 50.1 bits (118), Expect = 5e-06 Identities = 31/97 (31%), Positives = 49/97 (50%), Gaps = 5/97 (5%) Frame = -2 Query: 562 VXTREGKEFDIXKGHXVATSXAFANRLPHIFKNPDSY-DPDRFAAGR----EEDKVAGAF 398 + RE + DI GH + + HI +P + DPDRF GR D+ A Sbjct: 340 IIAREAVDDDIIDGHRIRRGTTVVIPIHHIHHDPRWWPDPDRFDPGRFLRCPTDRPRCA- 398 Query: 397 SYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL 287 Y+ FGGGR C+G+ FA +++ + + ++F F+L Sbjct: 399 -YLPFGGGRRICIGQSFALMEMVLMAAIMSQHFTFDL 434
>CP6J1_BLAGE (Q964R1) Cytochrome P450 6j1 (EC 1.14.-.-) (CYPVIJ1)| Length = 501 Score = 49.7 bits (117), Expect = 6e-06 Identities = 26/68 (38%), Positives = 39/68 (57%) Frame = -2 Query: 472 FKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEF 293 F +P +DP+RF+ +++ F+Y+ FG G C+G F +Q+KA H+L NFE Sbjct: 410 FPSPAKFDPERFSEKNKQN--IPHFAYMPFGEGPRNCIGMRFGSMQVKAALIHILSNFE- 466 Query: 292 ELVSPFPE 269 VSP E Sbjct: 467 --VSPCKE 472
>CP39A_MOUSE (Q9JKJ9) Cytochrome P450 39A1 (EC 1.14.13.99)| (24-hydroxycholesterol 7-alpha-hydroxylase) (Oxysterol 7-alpha-hydroxylase) (mCYP39A1) Length = 470 Score = 49.7 bits (117), Expect = 6e-06 Identities = 32/112 (28%), Positives = 56/112 (50%), Gaps = 3/112 (2%) Frame = -2 Query: 532 IXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGE 353 + G + S + +R P F P+S+ P+R+ DK +++FGGG+ C G Sbjct: 360 VPSGDLLMLSPFWLHRNPKYFPEPESFKPERWKEANL-DKYIFLDYFMAFGGGKFQCPGR 418 Query: 352 PFAYLQIKAIWTHLLRNFEFELVSPFPENDWNAMVVGI---KGEVMVNYKRR 206 FA L+I+ +L +E L+ P P+ + +VG+ G+ + YK+R Sbjct: 419 WFALLEIQLCIILVLYKYECSLLDPLPKQS-SRHLVGVPQPAGKCRIEYKQR 469
>C4D14_DROME (O46051) Probable cytochrome P450 4d14 (EC 1.14.-.-) (CYPIVD14)| Length = 507 Score = 49.3 bits (116), Expect = 8e-06 Identities = 23/66 (34%), Positives = 39/66 (59%) Frame = -2 Query: 493 ANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTH 314 A R P F +P+ + PDRF+ R+ + F+Y F G C+G+ FA L++K+ + Sbjct: 413 AQRDPDYFPDPEKFIPDRFSMERKGE--ISPFAYTPFSAGPRNCIGQKFAMLEMKSTISK 470 Query: 313 LLRNFE 296 ++R+FE Sbjct: 471 MVRHFE 476
>CP51_YEAST (P10614) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (P450-14DM) Length = 530 Score = 49.3 bits (116), Expect = 8e-06 Identities = 34/125 (27%), Positives = 55/125 (44%), Gaps = 16/125 (12%) Frame = -2 Query: 532 IXKGHXVATSXAFANRLPHIFKNPDSYDPDR--------FAAGREEDKVAGAFS------ 395 I G+ V S + + F N ++ R ++ G E D GA S Sbjct: 400 IPAGYHVLVSPGYTHLRDEYFPNAHQFNIHRWNKDSASSYSVGEEVDYGFGAISKGVSSP 459 Query: 394 YISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELV--SPFPENDWNAMVVGIKGEVMV 221 Y+ FGGGRH C+GE FAY Q+ + + +R ++ P D+ +MV G + Sbjct: 460 YLPFGGGRHRCIGEHFAYCQLGVLMSIFIRTLKWHYPEGKTVPPPDFTSMVTLPTGPAKI 519 Query: 220 NYKRR 206 +++R Sbjct: 520 IWEKR 524
>CP11A_MESAU (Q9EPT4) Cytochrome P450 11A1, mitochondrial precursor (EC| 1.14.15.6) (CYPXIA1) (P450(scc)) (Cholesterol side-chain cleavage enzyme) (Cholesterol desmolase) Length = 520 Score = 49.3 bits (116), Expect = 8e-06 Identities = 27/69 (39%), Positives = 36/69 (52%) Frame = -2 Query: 487 RLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLL 308 R P F NP+ +DP R+ E+ K F Y+SFG G CLG A L++ ++L Sbjct: 420 REPSFFPNPNKFDPTRWL---EKSKNTTHFRYLSFGWGVRQCLGRRIAELEMTIFLINVL 476 Query: 307 RNFEFELVS 281 NF EL S Sbjct: 477 ENFRIELQS 485
>C4AC1_DROME (Q9VMS9) Probable cytochrome P450 4ac1 (EC 1.14.-.-) (CYPIVAC1)| Length = 509 Score = 48.9 bits (115), Expect = 1e-05 Identities = 22/64 (34%), Positives = 36/64 (56%) Frame = -2 Query: 487 RLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLL 308 R P F PD + PDRF ++ F+Y+ F G+ C+G+ FA L++K + ++ Sbjct: 415 RDPRHFPKPDLFQPDRFLPENTVNR--HPFAYVPFSAGQRNCIGQKFAILEMKVLLAAVI 472 Query: 307 RNFE 296 RNF+ Sbjct: 473 RNFK 476
>CP3A9_RAT (P51538) Cytochrome P450 3A9 (EC 1.14.14.1) (CYPIIIA9) (P450-OLF3)| (Olfactive) (3AH15) Length = 503 Score = 48.5 bits (114), Expect = 1e-05 Identities = 23/81 (28%), Positives = 41/81 (50%) Frame = -2 Query: 532 IXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGE 353 I KG V ++ PH + P+ + P+RF+ +++ + Y+ FG G C+G Sbjct: 388 IPKGTVVMIPTFALHKDPHYWPEPEEFRPERFSKKNQDN--INPYMYLPFGNGPRNCIGM 445 Query: 352 PFAYLQIKAIWTHLLRNFEFE 290 FA + +K +L+NF F+ Sbjct: 446 RFALMNMKVALFRVLQNFSFQ 466
>CP3A6_RABIT (P11707) Cytochrome P450 3A6 (EC 1.14.14.1) (CYPIIIA6) (P450-3C)| Length = 501 Score = 48.5 bits (114), Expect = 1e-05 Identities = 27/82 (32%), Positives = 40/82 (48%) Frame = -2 Query: 532 IXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGE 353 I KG V +R P + PD + P+RF+ +++ + Y FG G CLG Sbjct: 386 IPKGTIVMMPTYALHRDPQHWTEPDEFRPERFSKKNKDN--INPYIYHPFGAGPRNCLGM 443 Query: 352 PFAYLQIKAIWTHLLRNFEFEL 287 FA + IK L++NF F+L Sbjct: 444 RFALMNIKLALVRLMQNFSFKL 465
>CP9B1_DROME (Q9V4I0) Cytochrome P450 9b1 (EC 1.14.-.-) (CYPIXB1)| Length = 505 Score = 48.1 bits (113), Expect = 2e-05 Identities = 21/73 (28%), Positives = 40/73 (54%) Frame = -2 Query: 472 FKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEF 293 F P +DP+RF+ R++D + ++Y+ FG G C+G +A +Q K + +L+ N++ Sbjct: 415 FPQPQRFDPERFSERRKKDLIP--YTYLPFGVGPRSCIGNRYAVMQAKGMLYNLMLNYKI 472 Query: 292 ELVSPFPENDWNA 254 E + W + Sbjct: 473 EASPRTTRDMWES 485
>CP3AS_BOVIN (P79102) Cytochrome P450 3A28 (EC 1.14.14.1) (CYPIIIA28)| Length = 507 Score = 48.1 bits (113), Expect = 2e-05 Identities = 24/81 (29%), Positives = 39/81 (48%) Frame = -2 Query: 532 IXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGE 353 I KG V + P ++ P+ + P+RF+ ++ + Y+ FG G CLG Sbjct: 388 IPKGTTVLVPLFVLHNNPELWPEPEEFRPERFSKNNKDS--INPYVYLPFGTGPRNCLGM 445 Query: 352 PFAYLQIKAIWTHLLRNFEFE 290 FA + IK +L+NF F+ Sbjct: 446 RFAIMNIKLALVRILQNFSFK 466
>CP3AR_ONCMY (O42563) Cytochrome P450 3A27 (EC 1.14.14.1) (CYPIIIA27)| Length = 518 Score = 48.1 bits (113), Expect = 2e-05 Identities = 21/68 (30%), Positives = 39/68 (57%) Frame = -2 Query: 490 NRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHL 311 +R P I+ +P+ + P+RF+ +E + ++Y+ FG G C+G FA + IK + Sbjct: 407 HRDPEIWSDPEEFKPERFS--KENKESIDPYTYMPFGAGPRNCIGMRFALIMIKLAMVEI 464 Query: 310 LRNFEFEL 287 L++F F + Sbjct: 465 LQSFTFSV 472
>CP6B5_PAPGL (Q95036) Cytochrome P450 6B5 (EC 1.14.14.1) (CYPVIB5) (CYP6B5V1)| (Fragment) Length = 476 Score = 47.8 bits (112), Expect = 2e-05 Identities = 27/86 (31%), Positives = 40/86 (46%) Frame = -2 Query: 547 GKEFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRH 368 G + KG V S + P + +P+ +DP+RF+ ++ A YI FG G+ Sbjct: 384 GTNVTLKKGQTVVVSGFGIHYDPKYYPDPEKFDPERFSPENVRNRHPCA--YIPFGAGQR 441 Query: 367 GCLGEPFAYLQIKAIWTHLLRNFEFE 290 CLG F Q++ LL F FE Sbjct: 442 KCLGMRFGQWQVQVCIIKLLSKFRFE 467
>CP6B4_PAPGL (Q27902) Cytochrome P450 6B4 (EC 1.14.14.1) (CYPVIB4)| (CYP6B4V1/CYP6B4V2) Length = 500 Score = 47.8 bits (112), Expect = 2e-05 Identities = 27/86 (31%), Positives = 40/86 (46%) Frame = -2 Query: 547 GKEFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRH 368 G + KG V S + P + +P+ +DP+RF+ ++ A YI FG G+ Sbjct: 384 GTNVTLKKGQTVVVSGFGIHYDPKYYPDPEKFDPERFSPENVRNRHPCA--YIPFGAGQR 441 Query: 367 GCLGEPFAYLQIKAIWTHLLRNFEFE 290 CLG F Q++ LL F FE Sbjct: 442 KCLGMRFGQWQVQVCIIKLLSKFRFE 467
>CP4E5_DROMT (O44221) Cytochrome P450 4e5, mitochondrial precursor (EC 1.14.-.-)| (CYPIVE5) Length = 522 Score = 47.8 bits (112), Expect = 2e-05 Identities = 21/60 (35%), Positives = 34/60 (56%) Frame = -2 Query: 475 IFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFE 296 +F+ P + P+RF E + G F Y+ F G C+G+ FA L++K + + L+R FE Sbjct: 411 VFEEPHRFYPERF-----EKQKPGPFEYVPFSAGPRNCIGQKFALLELKTVISKLVRTFE 465
>C4AC2_DROME (Q9VMS8) Probable cytochrome P450 4ac2 (EC 1.14.-.-) (CYPIVAC2)| Length = 497 Score = 47.8 bits (112), Expect = 2e-05 Identities = 26/91 (28%), Positives = 47/91 (51%), Gaps = 1/91 (1%) Frame = -2 Query: 472 FKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEF 293 F NP + PDRF ++ F+++ F G+ C+G+ FA L+IK + ++RNF+ Sbjct: 407 FSNPKMFQPDRFFPENTVNR--HPFAFVPFSAGQRNCIGQKFAILEIKVLLAAVIRNFKI 464 Query: 292 ELVSPFPENDW-NAMVVGIKGEVMVNYKRRK 203 V+ + + N +V+ K + V R+ Sbjct: 465 LPVTLLDDLTFENGIVLRTKQNIKVKLVHRE 495
>CP51_CANGA (P50859) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Sterol 14-alpha-demethylase) (Lanosterol 14-alpha demethylase) (P450-14DM) Length = 533 Score = 47.4 bits (111), Expect = 3e-05 Identities = 32/127 (25%), Positives = 57/127 (44%), Gaps = 18/127 (14%) Frame = -2 Query: 532 IXKGHXVATSXAFANRLPHIFKNPDSYDPDRF---------AAGREEDKVAGAFS----- 395 + + + V S + + F P+ ++ R+ A G E D GA S Sbjct: 401 VPRDYHVLVSPGYTHLQEEFFPKPNEFNIHRWDGDAASSSAAGGDEVDYGFGAISKGVSS 460 Query: 394 -YISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVS---PFPENDWNAMVVGIKGEV 227 Y+ FGGGRH C+GE FAY Q+ + + +R ++ + P +D+ +MV Sbjct: 461 PYLPFGGGRHRCIGELFAYCQLGVLMSIFIRTMKWRYPTEGETVPPSDFTSMVTLPTAPA 520 Query: 226 MVNYKRR 206 + +++R Sbjct: 521 KIYWEKR 527
>CP3AT_PIG (P79401) Cytochrome P450 3A29 (EC 1.14.14.1) (CYPIIIA29)| Length = 503 Score = 47.4 bits (111), Expect = 3e-05 Identities = 22/81 (27%), Positives = 41/81 (50%) Frame = -2 Query: 532 IXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGE 353 + KG V +R P ++ P+ + P+RF+ ++ ++Y+ FG G C+G Sbjct: 388 VPKGTVVVVPVFVLHRDPDLWPEPEEFRPERFS--KKHKDTINPYTYLPFGTGPRNCIGM 445 Query: 352 PFAYLQIKAIWTHLLRNFEFE 290 FA + +K +L+NF F+ Sbjct: 446 RFALMNMKLALVRVLQNFSFK 466
>CP6W1_DROME (Q9V9L1) Probable cytochrome P450 6w1 (EC 1.14.-.-) (CYPVIW1)| Length = 514 Score = 47.4 bits (111), Expect = 3e-05 Identities = 25/81 (30%), Positives = 39/81 (48%) Frame = -2 Query: 535 DIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLG 356 ++ G + S +R P + +P+ YDP+RF + ++ A Y+ FG G C+G Sbjct: 395 ELPHGMSIYMSTVAVHRDPQYWPDPEKYDPERFNSSNRDNLNMDA--YMPFGVGPRNCIG 452 Query: 355 EPFAYLQIKAIWTHLLRNFEF 293 LQ K H+LRN F Sbjct: 453 MRLGLLQSKLGLVHILRNHRF 473
>CP3AB_MOUSE (Q64459) Cytochrome P450 3A11 (EC 1.14.14.1) (CYPIIIA11)| (P-450IIIAM1) (P-450UT) Length = 504 Score = 47.4 bits (111), Expect = 3e-05 Identities = 24/81 (29%), Positives = 39/81 (48%) Frame = -2 Query: 532 IXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGE 353 I KG V + P + P+ + P+RF+ +E + Y+ FG G CLG Sbjct: 389 IPKGSTVMIPSYALHHDPQHWSEPEEFQPERFS--KENKGSIDPYVYLPFGNGPRNCLGM 446 Query: 352 PFAYLQIKAIWTHLLRNFEFE 290 FA + +K T +++NF F+ Sbjct: 447 RFALMNMKLALTKIMQNFSFQ 467
>C28A5_DROME (Q9V419) Probable cytochrome P450 28a5 (EC 1.14.-.-) (CYPXXVIIIA5)| Length = 505 Score = 47.4 bits (111), Expect = 3e-05 Identities = 30/121 (24%), Positives = 53/121 (43%), Gaps = 3/121 (2%) Frame = -2 Query: 562 VXTREGKEFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISF 383 + +EG F + KG V F NP S+ P+RF ++ F Sbjct: 384 IPNKEGPNFVVEKGTTVVVPHYCFMLDEEFFPNPQSFQPERFLEPDAAKTFRERGVFMGF 443 Query: 382 GGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPF-PENDW--NAMVVGIKGEVMVNYK 212 G G C+G FA +QIKA L+ F ++ +ND+ ++ G++G + ++ + Sbjct: 444 GDGPRVCIGMRFATVQIKAAIVELISKFNVKINDKTRKDNDYEPGQIITGLRGGIWLDLE 503 Query: 211 R 209 + Sbjct: 504 K 504
>CP17A_FELCA (Q9GMC8) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 47.4 bits (111), Expect = 3e-05 Identities = 31/115 (26%), Positives = 49/115 (42%), Gaps = 2/115 (1%) Frame = -2 Query: 541 EFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGC 362 EF + KG V + + + PD + P+RF ++ + SY+ FG G C Sbjct: 383 EFAVDKGTNVIINLWALHHNEKEWYRPDQFMPERFLDPTRSQLISPSLSYLPFGAGPRSC 442 Query: 361 LGEPFAYLQIKAIWTHLLRNFEFELV--SPFPENDWNAMVVGIKGEVMVNYKRRK 203 LGE A ++ LL+ F+ E+ P + N VV + V K R+ Sbjct: 443 LGESLARQEVFLFMAWLLQRFDLEVPDDGQLPHLEGNPTVVFLIAPFKVKVKVRQ 497
>CP4AA_MOUSE (O88833) Cytochrome P450 4A10 (EC 1.14.15.3) (CYPIVA10) (Lauric| acid omega-hydroxylase) (P450-LA-omega 1) (P452) Length = 509 Score = 47.4 bits (111), Expect = 3e-05 Identities = 26/77 (33%), Positives = 38/77 (49%) Frame = -2 Query: 526 KGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPF 347 KG V S + P ++ NP+ +DP RFA D + S++ F GG C+G+ F Sbjct: 406 KGVQVTLSIYGLHHNPKVWPNPEVFDPSRFAP----DSPRHSHSFLPFSGGARNCIGKQF 461 Query: 346 AYLQIKAIWTHLLRNFE 296 A ++K I L FE Sbjct: 462 AMSELKVIVALTLLRFE 478
>CP4AA_RAT (P08516) Cytochrome P450 4A10 (EC 1.14.15.3) (CYPIVA10) (Lauric| acid omega-hydroxylase) (P450-LA-omega 1) (P452) Length = 509 Score = 47.0 bits (110), Expect = 4e-05 Identities = 26/77 (33%), Positives = 38/77 (49%) Frame = -2 Query: 526 KGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPF 347 KG V S + P ++ NP+ +DP RFA D + S++ F GG C+G+ F Sbjct: 406 KGIQVTLSIYGLHHNPKVWPNPEVFDPSRFAP----DSPRHSHSFLPFSGGARNCIGKQF 461 Query: 346 AYLQIKAIWTHLLRNFE 296 A ++K I L FE Sbjct: 462 AMSEMKVIVALTLLRFE 478
>CP17A_SQUAC (Q92113) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 509 Score = 47.0 bits (110), Expect = 4e-05 Identities = 26/93 (27%), Positives = 46/93 (49%) Frame = -2 Query: 541 EFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGC 362 ++ I KG V + + +KNPD++DP RF + + + SY+ FG G C Sbjct: 386 DYTIPKGTRVIINLWAIHHDEKEWKNPDAFDPGRFLDEDGKYVCSSSESYLPFGAGTRVC 445 Query: 361 LGEPFAYLQIKAIWTHLLRNFEFELVSPFPEND 263 LGE A +++ + +L+ F ++ +P D Sbjct: 446 LGEMLARMELFLFTSWILQRFTVQVPPGYPPPD 478
>C4D20_DROME (Q9W011) Probable cytochrome P450 4d20 (EC 1.14.-.-) (CYPIVD20)| Length = 510 Score = 47.0 bits (110), Expect = 4e-05 Identities = 22/67 (32%), Positives = 40/67 (59%) Frame = -2 Query: 496 FANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWT 317 +A+R + F +P S+ P+RF +E+ F+Y+ F G C+G+ FA L++K + + Sbjct: 413 YAHRDANYFPDPLSFRPERFLEDQEQGH--NTFAYVPFSAGPKNCIGQKFAVLEMKVLIS 470 Query: 316 HLLRNFE 296 +LR +E Sbjct: 471 KVLRFYE 477
>CP26A_BRARE (P79739) Cytochrome P450 26A1 (EC 1.14.-.-) (Retinoic| acid-metabolizing cytochrome) (P450RAI) (Retinoic acid 4-hydroxylase) Length = 492 Score = 47.0 bits (110), Expect = 4e-05 Identities = 27/85 (31%), Positives = 42/85 (49%) Frame = -2 Query: 556 TREGKEFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGG 377 T E + I KG V S + + +F N + + P+RF + ED F+YI FGG Sbjct: 376 TFELNGYQIPKGWNVIYSICDTHDVADVFPNKEEFQPERFMSKGLED--GSRFNYIPFGG 433 Query: 376 GRHGCLGEPFAYLQIKAIWTHLLRN 302 G C+G+ FA + +K L ++ Sbjct: 434 GSRMCVGKEFAKVLLKIFLVELTQH 458
>CP11A_CAPHI (P79153) Cytochrome P450 11A1, mitochondrial precursor (EC| 1.14.15.6) (CYPXIA1) (P450(scc)) (Cholesterol side-chain cleavage enzyme) (Cholesterol desmolase) Length = 520 Score = 47.0 bits (110), Expect = 4e-05 Identities = 24/67 (35%), Positives = 37/67 (55%) Frame = -2 Query: 487 RLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLL 308 R P F NPD +DP R+ G+++D + F + FG G C+G A L++ H+L Sbjct: 423 RDPAFFSNPDKFDPTRWL-GKDKDLIH--FRNLGFGWGVRQCVGRRIAELEMTLFLIHIL 479 Query: 307 RNFEFEL 287 NF+ E+ Sbjct: 480 ENFKIEM 486
>CP4P3_DROME (Q9V559) Probable cytochrome P450 4p3 (EC 1.14.-.-) (CYPIVP3)| Length = 515 Score = 47.0 bits (110), Expect = 4e-05 Identities = 29/114 (25%), Positives = 53/114 (46%), Gaps = 6/114 (5%) Frame = -2 Query: 526 KGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPF 347 KG + +R P + +P+ + P+RF +++ ++YI F G+ C+G+ F Sbjct: 409 KGSQIFVHVFDIHRNPEYWDSPEEFRPERFLPENSQNR--HTYAYIPFSAGQRNCIGQKF 466 Query: 346 AYLQIKAIWTHLLRNFEFELVSPFPENDWNAMV------VGIKGEVMVNYKRRK 203 A ++K + LL+ F+ PE D +V + K ++ V RRK Sbjct: 467 AMQEMKTLMVALLKQFQI-----LPEIDPKTIVFQTGLTLRTKNQIHVKLVRRK 515
>CP3AO_SHEEP (Q29496) Cytochrome P450 3A24 (EC 1.14.14.1) (CYPIIIA24)| Length = 503 Score = 47.0 bits (110), Expect = 4e-05 Identities = 24/81 (29%), Positives = 42/81 (51%) Frame = -2 Query: 532 IXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGE 353 I KG V +R P ++ P+ + P+RF+ + +D + + Y+ FG G C+G Sbjct: 388 IPKGTAVTVPIFVLHRDPQLWPEPEEFRPERFSK-KNKDSI-NPYVYLPFGTGPRNCIGM 445 Query: 352 PFAYLQIKAIWTHLLRNFEFE 290 FA + +K +L+NF F+ Sbjct: 446 RFAIMNMKLAIVRVLQNFSFK 466
>CP6A8_DROME (Q27593) Cytochrome P450 6a8 (EC 1.14.-.-) (CYPVIA8)| Length = 506 Score = 47.0 bits (110), Expect = 4e-05 Identities = 30/104 (28%), Positives = 48/104 (46%), Gaps = 3/104 (2%) Frame = -2 Query: 538 FDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCL 359 F I G V + + P I+ P + P+RF+ EE + +++ FG G C+ Sbjct: 395 FVIEAGQSVIIPSSAIHHDPSIYPEPFEFRPERFSP--EESAGRPSVAWLPFGDGPRNCI 452 Query: 358 GEPFAYLQIKAIWTHLLRNFEFELVSPFPE---NDWNAMVVGIK 236 G F +Q + L+RNF+F S P D + V+G+K Sbjct: 453 GLRFGQMQARIGLALLIRNFKFSTCSKTPNPLVYDPKSFVLGVK 496
>CP17A_ICTPU (O73853) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 514 Score = 47.0 bits (110), Expect = 4e-05 Identities = 27/93 (29%), Positives = 44/93 (47%), Gaps = 2/93 (2%) Frame = -2 Query: 541 EFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGC 362 E+ + KG V + + +KNP+ ++P+RF + SY+ FG G C Sbjct: 386 EYTVQKGTRVIVNLWSLHHDEKEWKNPELFNPERFLNEEGNSLCCPSLSYLPFGAGVRVC 445 Query: 361 LGEPFAYLQIKAIWTHLLRNFEFELV--SPFPE 269 LGE A L++ + +L+ F E+ P PE Sbjct: 446 LGEALAKLELFLFLSWILQRFTLEVPGGQPLPE 478
>C76A1_SOLME (P37121) Cytochrome P450 76A1 (EC 1.14.-.-) (CYPLXXVIA1) (P-450EG8)| (Fragment) Length = 467 Score = 46.6 bits (109), Expect = 5e-05 Identities = 29/90 (32%), Positives = 43/90 (47%), Gaps = 3/90 (3%) Frame = -2 Query: 538 FDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCL 359 +DI KG V + R P + NP + P+RF + + K + I FG GR C+ Sbjct: 353 YDIPKGTQVLVNAWAIGRDPEYWDNPFEFKPERFLESKVDVKGQN-YELIPFGAGRRMCV 411 Query: 358 GEPFAYLQIKAIWTHLLRNFEFEL---VSP 278 G P + + + LL F++EL VSP Sbjct: 412 GLPLGHRMMHFTFGSLLHEFDWELPHNVSP 441
>CP3A1_RAT (P04800) Cytochrome P450 3A1 (EC 1.14.14.1) (CYPIIIA1) (P450-PCN1)| Length = 504 Score = 46.6 bits (109), Expect = 5e-05 Identities = 24/79 (30%), Positives = 39/79 (49%) Frame = -2 Query: 526 KGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPF 347 KG V +R P + P+ + P+RF+ +E + Y+ FG G C+G F Sbjct: 391 KGSVVMIPSYALHRDPQHWPEPEEFRPERFS--KENKGSIDPYVYLPFGNGPRNCIGMRF 448 Query: 346 AYLQIKAIWTHLLRNFEFE 290 A + +K T +L+NF F+ Sbjct: 449 ALMNMKLALTKVLQNFSFQ 467
>CP6U1_DROME (Q9V979) Probable cytochrome P450 6u1 (EC 1.14.-.-) (CYPVIU1)| Length = 488 Score = 46.6 bits (109), Expect = 5e-05 Identities = 28/85 (32%), Positives = 39/85 (45%) Frame = -2 Query: 547 GKEFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRH 368 G F I KG+ V A + P I++NP + P+RF + A AF + FG G Sbjct: 371 GSVFVIAKGNNVLIPTAAIHMDPGIYENPQRFYPERFEEQARRSRPAAAF--LPFGDGLR 428 Query: 367 GCLGEPFAYLQIKAIWTHLLRNFEF 293 GC+ FA Q+ LLR + Sbjct: 429 GCIAARFAEQQLLVGLVALLRQHRY 453
>CP4V2_PONPY (Q5RCN6) Cytochrome P450 4V2 (EC 1.14.-.-)| Length = 525 Score = 46.6 bits (109), Expect = 5e-05 Identities = 23/83 (27%), Positives = 41/83 (49%) Frame = -2 Query: 538 FDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCL 359 + + KG +R P F NP+ + P+RF + + ++Y+ F G C+ Sbjct: 411 YRVLKGTEAVIIPYALHRDPRYFPNPEEFQPERFFPENAQGR--HPYAYVPFSAGPRNCI 468 Query: 358 GEPFAYLQIKAIWTHLLRNFEFE 290 G+ FA ++ K I + +LR+F E Sbjct: 469 GQKFAVMEEKTILSCILRHFWIE 491
>CP4V2_HUMAN (Q6ZWL3) Cytochrome P450 4V2 (EC 1.14.-.-)| Length = 525 Score = 46.6 bits (109), Expect = 5e-05 Identities = 23/83 (27%), Positives = 41/83 (49%) Frame = -2 Query: 538 FDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCL 359 + + KG +R P F NP+ + P+RF + + ++Y+ F G C+ Sbjct: 411 YRVLKGTEAVIIPYALHRDPRYFPNPEEFQPERFFPENAQGR--HPYAYVPFSAGPRNCI 468 Query: 358 GEPFAYLQIKAIWTHLLRNFEFE 290 G+ FA ++ K I + +LR+F E Sbjct: 469 GQKFAVMEEKTILSCILRHFWIE 491
>C98A1_SORBI (O48956) Cytochrome P450 98A1 (EC 1.14.-.-)| Length = 512 Score = 46.6 bits (109), Expect = 5e-05 Identities = 31/97 (31%), Positives = 44/97 (45%), Gaps = 1/97 (1%) Frame = -2 Query: 538 FDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGA-FSYISFGGGRHGC 362 +DI KG V + R P ++ NP Y P+RF E + G+ F + FG GR C Sbjct: 384 YDIPKGANVMVNVWAVARDPKVWSNPLEYRPERFL--EENIDIKGSDFRVLPFGAGRRVC 441 Query: 361 LGEPFAYLQIKAIWTHLLRNFEFELVSPFPENDWNAM 251 G + ++ HLL +FE+ L D N M Sbjct: 442 PGAQLGINLVASMIGHLLHHFEWSLPEGTRPEDVNMM 478
>CP17A_PAPHU (Q9GLD2) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 46.2 bits (108), Expect = 7e-05 Identities = 31/115 (26%), Positives = 50/115 (43%), Gaps = 2/115 (1%) Frame = -2 Query: 541 EFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGC 362 EF + KG V + + + PD + P+RF ++ + SY+ FG G C Sbjct: 383 EFAVDKGTHVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSLSYLPFGAGPRSC 442 Query: 361 LGEPFAYLQIKAIWTHLLRNFEFELV--SPFPENDWNAMVVGIKGEVMVNYKRRK 203 +GE A ++ I LL+ F+ E+ P + N VV + V K R+ Sbjct: 443 IGEILARQELFLIMAWLLQRFDLEVPDDGQLPSLEGNPKVVFLIDSFKVKIKVRQ 497
>CP17A_PAPCY (Q8HYN0) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 46.2 bits (108), Expect = 7e-05 Identities = 31/115 (26%), Positives = 50/115 (43%), Gaps = 2/115 (1%) Frame = -2 Query: 541 EFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGC 362 EF + KG V + + + PD + P+RF ++ + SY+ FG G C Sbjct: 383 EFAVDKGTHVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSLSYLPFGAGPRSC 442 Query: 361 LGEPFAYLQIKAIWTHLLRNFEFELV--SPFPENDWNAMVVGIKGEVMVNYKRRK 203 +GE A ++ I LL+ F+ E+ P + N VV + V K R+ Sbjct: 443 IGEILARQELFLIMAWLLQRFDLEVPDDGQLPSLEGNPKVVFLIDSFKVKIKVRQ 497
>CP17A_MACMU (Q8HYM9) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 46.2 bits (108), Expect = 7e-05 Identities = 31/115 (26%), Positives = 50/115 (43%), Gaps = 2/115 (1%) Frame = -2 Query: 541 EFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGC 362 EF + KG V + + + PD + P+RF ++ + SY+ FG G C Sbjct: 383 EFAVDKGTHVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSLSYLPFGAGPRSC 442 Query: 361 LGEPFAYLQIKAIWTHLLRNFEFELV--SPFPENDWNAMVVGIKGEVMVNYKRRK 203 +GE A ++ I LL+ F+ E+ P + N VV + V K R+ Sbjct: 443 IGEILARQELFLIMAWLLQRFDLEVPDDGQLPSLEGNPKVVFLIDSFKVKIKVRQ 497
>CP17A_MACFA (Q2XVA1) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 46.2 bits (108), Expect = 7e-05 Identities = 31/115 (26%), Positives = 50/115 (43%), Gaps = 2/115 (1%) Frame = -2 Query: 541 EFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGC 362 EF + KG V + + + PD + P+RF ++ + SY+ FG G C Sbjct: 383 EFAVDKGTHVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSLSYLPFGAGPRSC 442 Query: 361 LGEPFAYLQIKAIWTHLLRNFEFELV--SPFPENDWNAMVVGIKGEVMVNYKRRK 203 +GE A ++ I LL+ F+ E+ P + N VV + V K R+ Sbjct: 443 IGEILARQELFLIMAWLLQRFDLEVPDDGQLPSLEGNPKVVFLIDSFKVKIKVRQ 497
>C6A14_DROME (Q9V4U7) Probable cytochrome P450 6a14 (EC 1.14.-.-) (CYPVIA14)| Length = 509 Score = 46.2 bits (108), Expect = 7e-05 Identities = 24/65 (36%), Positives = 33/65 (50%) Frame = -2 Query: 481 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 302 P I+ P+ +DP RF EE K +Y+ FG G C+G F +Q K LLR Sbjct: 417 PEIYPEPEKFDPSRFDP--EEVKNRHPMAYLPFGDGPRNCIGLRFGKIQAKIGLVSLLRR 474 Query: 301 FEFEL 287 F+F + Sbjct: 475 FKFSV 479
>CP6B3_PAPPO (Q27756) Cytochrome P450 6B3 (EC 1.14.14.1) (CYPVIB4)| (CYP6B3V1/CYP6B3V2) Length = 498 Score = 46.2 bits (108), Expect = 7e-05 Identities = 36/122 (29%), Positives = 49/122 (40%), Gaps = 8/122 (6%) Frame = -2 Query: 547 GKEFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRH 368 G + I KG + S P + NP+ +DP+RF E K +Y+ F G Sbjct: 384 GTDITIKKGQTIIVSTWGIQNDPKYYPNPEKFDPERF--NPENIKNRHPCAYLPFSAGPR 441 Query: 367 GCLGEPFAYLQIKAIWTHLLRNFEFELVSPFPEN--------DWNAMVVGIKGEVMVNYK 212 CLG FA QI+ +L + E P N D + V KG + VN Sbjct: 442 NCLGLRFAKWQIEVCVVKVLSKYRVE-----PSNKSSGEFKFDPMRLFVLPKGGIFVNIV 496 Query: 211 RR 206 RR Sbjct: 497 RR 498
>CP2DE_BOVIN (Q01361) Cytochrome P450 2D14 (EC 1.14.14.1) (CYPIID14) (Fragment)| Length = 487 Score = 46.2 bits (108), Expect = 7e-05 Identities = 29/95 (30%), Positives = 49/95 (51%), Gaps = 2/95 (2%) Frame = -2 Query: 550 EGKEFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRF--AAGREEDKVAGAFSYISFGG 377 E + F I KG + T+ + + +++ P + P+ F A GR + A +I F Sbjct: 373 EVQGFHIPKGTTLITNLSSVLKDETVWQKPFRFHPEHFLDAQGRFVKQEA----FIPFSA 428 Query: 376 GRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFP 272 GR CLGEP A +++ +T LL++F F + + P Sbjct: 429 GRRACLGEPLARMELFLFFTSLLQHFSFSVPAGQP 463
>C75A5_EUSGR (Q96418) Flavonoid 3',5'-hydroxylase (EC 1.14.13.88) (F3'5'H)| (Cytochrome P450 75A5) Length = 510 Score = 46.2 bits (108), Expect = 7e-05 Identities = 27/86 (31%), Positives = 43/86 (50%), Gaps = 2/86 (2%) Frame = -2 Query: 532 IXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREE--DKVAGAFSYISFGGGRHGCL 359 I KG ++ + R P +++NP+ ++PDRF + D F I FG GR C Sbjct: 389 IPKGTRLSVNIWAIGRDPSLWENPNEFNPDRFLERKNAKIDPRGNDFELIPFGAGRRICA 448 Query: 358 GEPFAYLQIKAIWTHLLRNFEFELVS 281 G L ++ I L+ +F++EL S Sbjct: 449 GTRLGILLVEYILGTLVHSFDWELPS 474
>CP3A2_RAT (P05183) Cytochrome P450 3A2 (EC 1.14.14.1) (CYPIIIA2) (P450-PCN2)| (P450/6-beta-A) (Testosterone 6-beta-hydroxylase) Length = 504 Score = 46.2 bits (108), Expect = 7e-05 Identities = 24/81 (29%), Positives = 39/81 (48%) Frame = -2 Query: 532 IXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGE 353 I KG V + P + P+ + P+RF+ +E + Y+ FG G C+G Sbjct: 389 IPKGSVVTIPTYALHHDPQHWPKPEEFHPERFS--KENKGSIDPYVYLPFGNGPRNCIGM 446 Query: 352 PFAYLQIKAIWTHLLRNFEFE 290 FA + +K T +L+NF F+ Sbjct: 447 RFALMNMKLALTKVLQNFSFQ 467
>CP6T3_DROME (Q9V676) Probable cytochrome P450 6t3 (EC 1.14.-.-) (CYPVIT3)| Length = 501 Score = 46.2 bits (108), Expect = 7e-05 Identities = 26/84 (30%), Positives = 39/84 (46%) Frame = -2 Query: 541 EFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGC 362 +F + G S +R + P +DP+RF G E + +YI FG G HGC Sbjct: 387 DFIVPPGMPAYISILGLHRDERFWPEPCVFDPERF--GPERSRHIHPMTYIPFGAGPHGC 444 Query: 361 LGEPFAYLQIKAIWTHLLRNFEFE 290 +G LQ+K H+L+ + E Sbjct: 445 IGSRLGVLQLKLGIVHILKQYWVE 468
>C97B3_ARATH (O23365) Cytochrome P450 97B3 (EC 1.14.-.-)| Length = 580 Score = 46.2 bits (108), Expect = 7e-05 Identities = 25/102 (24%), Positives = 45/102 (44%), Gaps = 20/102 (19%) Frame = -2 Query: 532 IXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAG----------------- 404 + KG + S +R P+ + NP ++P+RF +E + + G Sbjct: 449 VPKGTDIFISVYNLHRSPYFWDNPHDFEPERFLRTKESNGIEGWAGFDPSRSPGALYPNE 508 Query: 403 ---AFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL 287 F+++ FGGG C+G+ FA ++ L + F+ EL Sbjct: 509 IIADFAFLPFGGGPRKCIGDQFALMESTVALAMLFQKFDVEL 550
>CP11A_SHEEP (P79202) Cytochrome P450 11A1, mitochondrial precursor (EC| 1.14.15.6) (CYPXIA1) (P450(SCC)) (Cholesterol side-chain cleavage enzyme) (Cholesterol desmolase) Length = 520 Score = 46.2 bits (108), Expect = 7e-05 Identities = 24/67 (35%), Positives = 36/67 (53%) Frame = -2 Query: 487 RLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLL 308 R P F NPD +DP R+ G+++D + F + FG G C+G A L++ H+L Sbjct: 423 RDPAFFSNPDKFDPTRWL-GKDKDLIH--FRNLGFGWGVRQCVGRRIAELEMTLFLIHIL 479 Query: 307 RNFEFEL 287 NF E+ Sbjct: 480 ENFRVEM 486
>THAS_RAT (P49430) Thromboxane-A synthase (EC 5.3.99.5) (TXA synthase) (TXS)| Length = 533 Score = 45.8 bits (107), Expect = 9e-05 Identities = 24/65 (36%), Positives = 34/65 (52%), Gaps = 1/65 (1%) Frame = -2 Query: 481 PHIFKNPDSYDPDRFAA-GREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLR 305 P + NP+++DP+RF A R + K F+Y+ FG G CLG L +K +L Sbjct: 442 PEHWPNPETFDPERFTAEARLQQK---PFTYLPFGAGPRSCLGVRLGLLVVKLTLLQVLH 498 Query: 304 NFEFE 290 F FE Sbjct: 499 KFRFE 503
>THAS_HUMAN (P24557) Thromboxane-A synthase (EC 5.3.99.5) (TXA synthase) (TXS)| Length = 533 Score = 45.8 bits (107), Expect = 9e-05 Identities = 21/64 (32%), Positives = 35/64 (54%) Frame = -2 Query: 481 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 302 P + +P++++P+RF A E + F+Y+ FG G CLG L++K H+L Sbjct: 442 PEHWPSPETFNPERFTA--EARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHK 499 Query: 301 FEFE 290 F F+ Sbjct: 500 FRFQ 503
>CP2F2_MOUSE (P33267) Cytochrome P450 2F2 (EC 1.14.14.-) (CYPIIF2) (Naphthalene| dehydrogenase) (Naphthalene hydroxylase) (P450-NAH-2) Length = 491 Score = 45.8 bits (107), Expect = 9e-05 Identities = 30/88 (34%), Positives = 43/88 (48%), Gaps = 1/88 (1%) Frame = -2 Query: 538 FDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCL 359 F I KG V T + FK P ++P+ F K + AF + F GR CL Sbjct: 380 FLIPKGTDVITLLNTVHYDSDQFKTPQEFNPEHFLDDNHSFKKSPAF--MPFSAGRRLCL 437 Query: 358 GEPFAYLQIKAIWTHLLRNFEFE-LVSP 278 GEP A +++ +T +L+NF + LV P Sbjct: 438 GEPLARMELFIYFTSILQNFTLQPLVDP 465
>CP6B2_HELAM (Q27664) Cytochrome P450 6B2 (EC 1.14.14.1) (CYPVIB2)| Length = 504 Score = 45.8 bits (107), Expect = 9e-05 Identities = 38/121 (31%), Positives = 51/121 (42%), Gaps = 6/121 (4%) Frame = -2 Query: 547 GKEFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRH 368 G + I K V S + P + NP ++P+RF A EE +Y+ FG G+ Sbjct: 386 GTDVVIEKDTVVLISPRGIHYDPKYYDNPKQFNPERFFA--EEVGKRHPCAYLPFGLGQR 443 Query: 367 GCLGEPFAYLQIKAIWTHLLRNFEFELVSPFPENDWNAMV------VGIKGEVMVNYKRR 206 C+G F LQ T LL F E P D N V +G KG + +N R Sbjct: 444 NCIGMRFGRLQSLLCITKLLSKFRLE---PSKNTDRNLQVEPYRFIIGPKGGIRLNIVPR 500 Query: 205 K 203 K Sbjct: 501 K 501
>C28D2_DROME (Q9VMT6) Probable cytochrome P450 28d2 (EC 1.14.-.-) (CYPXXVIIID2)| Length = 501 Score = 45.8 bits (107), Expect = 9e-05 Identities = 32/122 (26%), Positives = 57/122 (46%), Gaps = 8/122 (6%) Frame = -2 Query: 553 REGKEFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRF----AAGREEDKVAGAFSYIS 386 + G+ + G V + P +++P ++ P+RF G + + G Y++ Sbjct: 381 KNGRTVHLKPGDVVTIPVKALHHDPQYYEDPLTFKPERFLESNGGGMKSYRDRGV--YLA 438 Query: 385 FGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFPENDWNA----MVVGIKGEVMVN 218 FG G C G FA Q+KA +LRNFE + V+P +D + +KG + ++ Sbjct: 439 FGDGPRHCPGMRFALTQLKAALVEILRNFEIK-VNPKTRSDNQIDDTFFMATLKGGIYLD 497 Query: 217 YK 212 +K Sbjct: 498 FK 499
>CP392_DROME (P82713) Probable cytochrome P450 309a2 (EC 1.14.-.-) (CYPCCCIXA2)| Length = 538 Score = 45.8 bits (107), Expect = 9e-05 Identities = 30/116 (25%), Positives = 53/116 (45%), Gaps = 2/116 (1%) Frame = -2 Query: 550 EGKEFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGR 371 E K D+ G + + F P+++ P+RF G ++ + ++ F G Sbjct: 422 ESKSLDVEVGMTIMIPNYQFHHDKQYFPEPEAFKPERFDNGAYQELMRKGI-FLPFSDGP 480 Query: 370 HGCLGEPFAYLQIKAIWTHLLRNFEFELVSP--FPENDWNAMVVGIKGEVMVNYKR 209 C+G P A L +K+ H+L NF+ P+ D VV ++G+V + Y+R Sbjct: 481 RICMGVPLAMLTLKSALVHILSNFQVVRGRDRLIPKGDSGFGVV-LQGDVNLEYRR 535
>C76A2_SOLME (P37122) Cytochrome P450 76A2 (EC 1.14.-.-) (CYPLXXVIA2) (P-450EG7)| Length = 505 Score = 45.8 bits (107), Expect = 9e-05 Identities = 30/90 (33%), Positives = 43/90 (47%), Gaps = 3/90 (3%) Frame = -2 Query: 538 FDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCL 359 +D+ K V + R P + +P S+ P+RF G + D + I FG GR C+ Sbjct: 391 YDVPKDTQVLVNAWAIGRDPECWDDPMSFKPERFL-GSKIDVKGQHYGLIPFGAGRRMCV 449 Query: 358 GEPFAYLQIKAIWTHLLRNFEFEL---VSP 278 G P + + LLR FE+EL VSP Sbjct: 450 GLPLGHRMMHFALGSLLREFEWELPDGVSP 479
>C77A1_SOLME (P37123) Cytochrome P450 77A1 (EC 1.14.-.-) (CYPLXXVIIA1)| (P-450EG6) (Fragment) Length = 499 Score = 45.8 bits (107), Expect = 9e-05 Identities = 20/65 (30%), Positives = 37/65 (56%), Gaps = 2/65 (3%) Frame = -2 Query: 481 PHIFKNPDSYDPDRFAAGREEDKVAGA--FSYISFGGGRHGCLGEPFAYLQIKAIWTHLL 308 P+++ +P+ +DPDRF +GRE+ + G + FG GR C G A + + + ++ Sbjct: 402 PNVWSDPEKFDPDRFLSGREDADITGVKEVKMMPFGVGRRICPGLGMATVHVNLMLARMV 461 Query: 307 RNFEF 293 + FE+ Sbjct: 462 QEFEW 466
>C71A2_SOLME (P37118) Cytochrome P450 71A2 (EC 1.14.-.-) (CYPLXXIA2) (P-450EG4)| Length = 505 Score = 45.4 bits (106), Expect = 1e-04 Identities = 28/83 (33%), Positives = 38/83 (45%), Gaps = 5/83 (6%) Frame = -2 Query: 520 HXVATSXAFAN-----RLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLG 356 H A + A N R P ++NP+ Y P+RF + D F + FG GR GC G Sbjct: 392 HIPARTQAIINAWAIGRDPLSWENPEEYQPERFL-NSDADVKGLNFKLLPFGAGRRGCPG 450 Query: 355 EPFAYLQIKAIWTHLLRNFEFEL 287 FA I+ L+ F+F L Sbjct: 451 SSFAIAVIELALARLVHKFDFAL 473
>CP4AC_MOUSE (Q91WL5) Cytochrome P450 4A12 (EC 1.14.14.1) (CYPIVA12)| Length = 508 Score = 45.4 bits (106), Expect = 1e-04 Identities = 25/77 (32%), Positives = 37/77 (48%) Frame = -2 Query: 526 KGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPF 347 KG V S + P ++ NP+ +DP RFA G + S++ F GG C+G+ F Sbjct: 405 KGIHVMLSFYGLHHNPTVWPNPEVFDPSRFAPGSSRH----SHSFLPFSGGARNCIGKQF 460 Query: 346 AYLQIKAIWTHLLRNFE 296 A ++K L FE Sbjct: 461 AMNELKVAVALTLLRFE 477
>CP311_DROME (Q9VYQ7) Probable cytochrome P450 311a1 (EC 1.14.-.-) (CYPCCCXIA1)| Length = 483 Score = 45.4 bits (106), Expect = 1e-04 Identities = 24/63 (38%), Positives = 38/63 (60%), Gaps = 1/63 (1%) Frame = -2 Query: 472 FKNPDSYDPDRFAAGREEDKVAG-AFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFE 296 + +P ++ P+R+ E+ VA AFSYI F GG H C+G ++ L +K + L+R F+ Sbjct: 395 YPDPYAFKPERWLP--EDGAVAPPAFSYIPFSGGPHVCIGRRYSLLLMKLLTARLVREFQ 452 Query: 295 FEL 287 EL Sbjct: 453 MEL 455
>CP317_DROME (Q9V776) Probable cytochrome P450 317a1 (EC 1.14.-.-)| (CYPCCCXVIIA1) Length = 518 Score = 45.4 bits (106), Expect = 1e-04 Identities = 22/65 (33%), Positives = 36/65 (55%) Frame = -2 Query: 481 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 302 P I+ +P+ + PDR++ R+ + G ++ FG G C+G FA LQ++ LL Sbjct: 424 PDIYPDPEEFKPDRWSGPRDSLQEQG--TWFGFGVGARSCIGIQFAQLQLRLALALLLSE 481 Query: 301 FEFEL 287 +EF L Sbjct: 482 YEFSL 486
>CP4C1_BLADI (P29981) Cytochrome P450 4C1 (EC 1.14.14.1) (CYPIVC1)| Length = 511 Score = 45.4 bits (106), Expect = 1e-04 Identities = 19/59 (32%), Positives = 35/59 (59%) Frame = -2 Query: 472 FKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFE 296 + NP++++PD F R + ++Y+ F G C+G+ FA L+ K + + +LRNF+ Sbjct: 418 YPNPEAFNPDNFLPERVAKR--HPYAYVPFSAGPRNCIGQKFATLEEKTVLSSILRNFK 474
>C76C4_ARATH (O64635) Cytochrome P450 76C4 (EC 1.14.-.-)| Length = 511 Score = 45.4 bits (106), Expect = 1e-04 Identities = 25/84 (29%), Positives = 42/84 (50%) Frame = -2 Query: 538 FDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCL 359 F + K V + R P +++NP ++P+RF G++ D + FGGGR C Sbjct: 393 FMVPKDTQVLVNVWAIGRDPSVWENPSQFEPERFM-GKDIDVKGRDYELTPFGGGRRICP 451 Query: 358 GEPFAYLQIKAIWTHLLRNFEFEL 287 G P A + + LL +F+++L Sbjct: 452 GLPLAVKTVSLMLASLLYSFDWKL 475
>CP11A_PIG (P10612) Cytochrome P450 11A1, mitochondrial precursor (EC| 1.14.15.6) (CYPXIA1) (P450(scc)) (Cholesterol side-chain cleavage enzyme) (Cholesterol desmolase) Length = 520 Score = 45.4 bits (106), Expect = 1e-04 Identities = 25/67 (37%), Positives = 35/67 (52%) Frame = -2 Query: 487 RLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLL 308 R P F NP +DP R+ G+E D + F + FG G C+G A L++ H+L Sbjct: 423 RDPAFFSNPGQFDPTRWL-GKERDLIH--FRNLGFGWGVRQCVGRRIAELEMTLFLIHIL 479 Query: 307 RNFEFEL 287 NF+ EL Sbjct: 480 ENFKVEL 486
>C71B6_ARATH (O65787) Cytochrome P450 71B6 (EC 1.14.-.-)| Length = 503 Score = 45.4 bits (106), Expect = 1e-04 Identities = 28/97 (28%), Positives = 43/97 (44%) Frame = -2 Query: 544 KEFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHG 365 K +DI G + + R P ++K+PD + P+RF E K +F + FG GR G Sbjct: 387 KGYDIYPGTRIHVNAWAIGRNPDVWKDPDEFIPERFVDSNVETK-GTSFELLPFGSGRRG 445 Query: 364 CLGEPFAYLQIKAIWTHLLRNFEFELVSPFPENDWNA 254 C P Y+ + + E+ L + DW A Sbjct: 446 C---PAMYVGLSTV--------EYTLANLLYHFDWKA 471
>CP137_MYCTU (O69653) Putative cytochrome P450 137 (EC 1.14.-.-)| Length = 476 Score = 45.4 bits (106), Expect = 1e-04 Identities = 24/90 (26%), Positives = 42/90 (46%) Frame = -2 Query: 538 FDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCL 359 + + G + NR ++++P + P+RF R + ++++ FGGG CL Sbjct: 369 YRVEAGTRIVVHIIAINRSAEVYEHPHEFRPERFLGTRPQ-----TYAWVPFGGGVKRCL 423 Query: 358 GEPFAYLQIKAIWTHLLRNFEFELVSPFPE 269 G F+ ++ + LLR EF V PE Sbjct: 424 GANFSMRELITVLHVLLREGEFTAVDDEPE 453
>CP11A_MOUSE (Q9QZ82) Cytochrome P450 11A1, mitochondrial precursor (EC| 1.14.15.6) (CYPXIA1) (P450(scc)) (Cholesterol side-chain cleavage enzyme) (Cholesterol desmolase) Length = 526 Score = 45.4 bits (106), Expect = 1e-04 Identities = 24/67 (35%), Positives = 35/67 (52%) Frame = -2 Query: 487 RLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLL 308 R P F NP+ +DP R+ E+ + F Y+ FG G CLG A L++ + +LL Sbjct: 420 RDPGFFPNPNKFDPTRWL---EKSQNTTHFRYLGFGWGVRQCLGRRIAELEMTILLINLL 476 Query: 307 RNFEFEL 287 NF E+ Sbjct: 477 ENFRIEV 483
>C99A1_SORBI (O48957) Cytochrome P450 CYP99A1 (EC 1.14.-.-) (Fragment)| Length = 519 Score = 45.1 bits (105), Expect = 1e-04 Identities = 27/90 (30%), Positives = 40/90 (44%), Gaps = 6/90 (6%) Frame = -2 Query: 538 FDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFA------AGREEDKVAGAFSYISFGG 377 F++ KG V + R P + +P+ + P+RFA A D F YI FG Sbjct: 389 FEVTKGTKVIVNAWALARSPERWHDPEEFRPERFADDDGSSAAVAVDYRGSQFEYIPFGS 448 Query: 376 GRHGCLGEPFAYLQIKAIWTHLLRNFEFEL 287 GR C G F ++ + LL F++ L Sbjct: 449 GRRMCPGNTFGLAALELMVARLLYYFDWSL 478
>CP2F2_RAT (O35293) Cytochrome P450 2F2 (EC 1.14.14.-) (CYPIIF2) (Naphthalene| dehydrogenase) (Naphthalene hydroxylase) (P450-NAH-2) Length = 491 Score = 45.1 bits (105), Expect = 1e-04 Identities = 30/88 (34%), Positives = 42/88 (47%), Gaps = 1/88 (1%) Frame = -2 Query: 538 FDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCL 359 F I KG V T + FK P ++P+ F + K + AF + F GR CL Sbjct: 380 FLIPKGTDVITLLNTVHYDSDQFKTPQEFNPEHFLDANQSFKKSPAF--MPFSAGRRLCL 437 Query: 358 GEPFAYLQIKAIWTHLLRNFEFE-LVSP 278 GEP A +++ T +L+NF LV P Sbjct: 438 GEPLARMELFIYLTSILQNFTLHPLVEP 465
>C75A7_EUSGR (O04790) Flavonoid 3',5'-hydroxylase (EC 1.14.13.88) (F3'5'H)| (Cytochrome P450 75A7) Length = 510 Score = 45.1 bits (105), Expect = 1e-04 Identities = 27/86 (31%), Positives = 42/86 (48%), Gaps = 2/86 (2%) Frame = -2 Query: 532 IXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREE--DKVAGAFSYISFGGGRHGCL 359 I KG ++ + R P +++NP+ ++PDRF + D F I FG GR C Sbjct: 389 IPKGTRLSVNIWAIGRDPSVWENPNEFNPDRFLERKNAKIDPRGNDFELIPFGAGRRICA 448 Query: 358 GEPFAYLQIKAIWTHLLRNFEFELVS 281 G L ++ I L+ +F +EL S Sbjct: 449 GTRLGILLVEYILGTLVHSFVWELPS 474
>CPXN_ANASP (P29980) Probable cytochrome P450 110 (EC 1.14.-.-)| Length = 459 Score = 45.1 bits (105), Expect = 1e-04 Identities = 23/70 (32%), Positives = 34/70 (48%) Frame = -2 Query: 475 IFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFE 296 ++ NP + P+RF ++ YI FGGG CLG A L+IK + +L N++ Sbjct: 361 LYPNPQQFRPERFI-----ERQYSPSEYIPFGGGSRRCLGYALALLEIKLVIATVLSNYQ 415 Query: 295 FELVSPFPEN 266 L P N Sbjct: 416 LALAEDKPVN 425
>CP341_MOUSE (Q9JMA7) Cytochrome P450 3A41 (EC 1.14.14.1)| Length = 504 Score = 45.1 bits (105), Expect = 1e-04 Identities = 23/81 (28%), Positives = 40/81 (49%) Frame = -2 Query: 532 IXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGE 353 I KG V + P + P+ + P+RF+ +E + Y+ FG G C+G Sbjct: 389 IPKGSTVMIPSYALHHDPQHWPEPEEFQPERFS--KENKGSIDPYLYMPFGIGPRNCIGM 446 Query: 352 PFAYLQIKAIWTHLLRNFEFE 290 FA++ +K T +++NF F+ Sbjct: 447 RFAFMTMKLALTKVMQNFSFQ 467
>CP9H1_DROME (Q9V6H1) Probable cytochrome P450 9h1 (EC 1.14.-.-) (CYPIXH1)| Length = 518 Score = 45.1 bits (105), Expect = 1e-04 Identities = 27/84 (32%), Positives = 43/84 (51%), Gaps = 1/84 (1%) Frame = -2 Query: 544 KEFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGRE-EDKVAGAFSYISFGGGRH 368 K F KG + + P F++P+ ++P+RFA G E +V Y+ FG G Sbjct: 406 KLFSARKGDVLQIPIFSLHHDPENFEDPEFFNPERFADGHALESRV-----YMPFGVGPR 460 Query: 367 GCLGEPFAYLQIKAIWTHLLRNFE 296 C+G A +++K+I LL NF+ Sbjct: 461 NCIGNRMALMELKSIVYQLLLNFK 484
>C77A2_SOLME (P37124) Cytochrome P450 77A2 (EC 1.14.-.-) (CYPLXXVIIA2)| (P-450EG5) Length = 511 Score = 45.1 bits (105), Expect = 1e-04 Identities = 25/84 (29%), Positives = 41/84 (48%), Gaps = 2/84 (2%) Frame = -2 Query: 538 FDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAG--AFSYISFGGGRHG 365 +DI G V + P+++ P+ +DPDRF G+E+ + G I FG GR Sbjct: 396 YDIPTGVNVEIFLPGISDDPNLWSEPEKFDPDRFYLGKEDADITGVSGVKMIPFGMGRRI 455 Query: 364 CLGEPFAYLQIKAIWTHLLRNFEF 293 C G A + + + L++ FE+ Sbjct: 456 CPGLNMATVHVSLMLARLVQEFEW 479
>THAS_MOUSE (P36423) Thromboxane-A synthase (EC 5.3.99.5) (TXA synthase) (TXS)| (TS) Length = 533 Score = 45.1 bits (105), Expect = 1e-04 Identities = 23/64 (35%), Positives = 32/64 (50%) Frame = -2 Query: 481 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 302 P + NP+++DP+RF A E F+Y+ FG G CLG L +K +L Sbjct: 442 PEHWPNPETFDPERFTA--EARLQRRPFTYLPFGAGPRSCLGVRLGLLVVKLTILQVLHK 499 Query: 301 FEFE 290 F FE Sbjct: 500 FRFE 503
>CP27A_RAT (P17178) Cytochrome P450 27, mitochondrial precursor (EC| 1.14.13.15) (Cytochrome P-450C27/25) (Sterol 26-hydroxylase) (Sterol 27-hydroxylase) (Vitamin D(3) 25-hydroxylase) (5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 27-hydroxylase) Length = 533 Score = 45.1 bits (105), Expect = 1e-04 Identities = 22/70 (31%), Positives = 38/70 (54%), Gaps = 2/70 (2%) Frame = -2 Query: 490 NRLPHIFKNPDSYDPDRFAAGREEDK--VAGAFSYISFGGGRHGCLGEPFAYLQIKAIWT 317 +R P +F P+S+ P R+ RE+D + F + FG G CLG A L+++ + + Sbjct: 435 SRDPSVFPEPESFQPHRWLRKREDDNSGIQHPFGSVPFGYGVRSCLGRRIAELEMQLLLS 494 Query: 316 HLLRNFEFEL 287 L++ +E L Sbjct: 495 RLIQKYEVVL 504
>C6A19_DROME (P82711) Probable cytochrome P450 6a19 (EC 1.14.-.-) (CYPVIA19)| Length = 503 Score = 45.1 bits (105), Expect = 1e-04 Identities = 30/111 (27%), Positives = 53/111 (47%), Gaps = 3/111 (2%) Frame = -2 Query: 541 EFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGC 362 ++ I G V S + P + P+ + P+RF E+ K +++ FG G C Sbjct: 388 KYFIEAGTGVLVSTLGIHHDPEFYPEPEKFIPERF--DEEQVKKRPTCAFLPFGAGPRNC 445 Query: 361 LGEPFAYLQIKAIWTHLLRNFEFEL--VSPFP-ENDWNAMVVGIKGEVMVN 218 +G F +Q+ L+ NF FEL +P P + N +++G +G + +N Sbjct: 446 IGLRFGRMQVIIGLALLIHNFRFELHPKTPVPMKYTINNLLLGSEGGIHLN 496
>CP51_UNCNE (O14442) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Sterol 14-alpha demethylase) (Eburicol 14-alpha-demethylase) (P450-14DM) Length = 524 Score = 44.7 bits (104), Expect = 2e-04 Identities = 32/102 (31%), Positives = 47/102 (46%), Gaps = 17/102 (16%) Frame = -2 Query: 547 GKEFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREE----DKV---------- 410 G ++ I H + +S ++ F +P +DP R+ G + D V Sbjct: 391 GTKYVIPTSHVLISSPGCTSQDATFFPDPLKWDPHRWDIGSGKVLGNDAVDEKYDYGYGL 450 Query: 409 --AGAFS-YISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEF 293 GA S Y+ FG GRH C+GE FA LQ+ I ++R F F Sbjct: 451 TSTGASSPYLPFGAGRHRCIGEQFATLQLVTIMATMVRFFRF 492
>CP3AC_CANFA (P24463) Cytochrome P450 3A12 (EC 1.14.14.1) (CYPIIIA12)| (P450-PBD-1) Length = 503 Score = 44.7 bits (104), Expect = 2e-04 Identities = 23/81 (28%), Positives = 40/81 (49%) Frame = -2 Query: 532 IXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGE 353 I KG V +R ++ P+ + P+RF+ R+ ++Y+ FG G C+G Sbjct: 388 IPKGTVVMVPTFTLHRDQSLWPEPEEFRPERFS--RKNKDSINPYTYLPFGTGPRNCIGM 445 Query: 352 PFAYLQIKAIWTHLLRNFEFE 290 FA + +K +L+NF F+ Sbjct: 446 RFAIMNMKLALVRVLQNFSFK 466
>C75A1_PETHY (P48418) Flavonoid 3',5'-hydroxylase 1 (EC 1.14.13.88) (F3'5'H)| (Cytochrome P450 75A1) (CYPLXXVA1) Length = 506 Score = 44.7 bits (104), Expect = 2e-04 Identities = 23/71 (32%), Positives = 38/71 (53%), Gaps = 2/71 (2%) Frame = -2 Query: 487 RLPHIFKNPDSYDPDRFAAGREE--DKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTH 314 R P +++NP ++P+RF +GR D F I FG GR C G + ++ I Sbjct: 400 RDPQVWENPLEFNPERFLSGRNSKIDPRGNDFELIPFGAGRRICAGTRMGIVMVEYILGT 459 Query: 313 LLRNFEFELVS 281 L+ +F+++L S Sbjct: 460 LVHSFDWKLPS 470
>CP2B6_HUMAN (P20813) Cytochrome P450 2B6 (EC 1.14.14.1) (CYPIIB6) (P450 IIB1)| Length = 491 Score = 44.7 bits (104), Expect = 2e-04 Identities = 26/73 (35%), Positives = 37/73 (50%) Frame = -2 Query: 481 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 302 PH F+ PD+++PD F K AF I F G+ CLGE A ++ +T +L+N Sbjct: 399 PHYFEKPDAFNPDHFLDANGALKKTEAF--IPFSLGKRICLGEGIARAELFLFFTTILQN 456 Query: 301 FEFELVSPFPEND 263 F + SP D Sbjct: 457 --FSMASPVAPED 467
>CP3AG_MOUSE (Q64481) Cytochrome P450 3A16 (EC 1.14.14.1) (CYPIIIA16)| Length = 504 Score = 44.7 bits (104), Expect = 2e-04 Identities = 23/81 (28%), Positives = 38/81 (46%) Frame = -2 Query: 532 IXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGE 353 I KG V + P + P+ + P+RF+ +E + Y+ FG G C+G Sbjct: 389 IPKGSTVIIPSYVLHHDPQHWPEPEEFQPERFS--KENKGSIDPYVYLPFGNGPRNCIGM 446 Query: 352 PFAYLQIKAIWTHLLRNFEFE 290 FA + +K +L+NF F+ Sbjct: 447 RFALMNMKLALIKVLQNFSFQ 467
>CP310_DROME (Q9VJ71) Probable cytochrome P450 310a1 (EC 1.14.-.-) (CYPCCCXA1)| Length = 492 Score = 44.7 bits (104), Expect = 2e-04 Identities = 38/123 (30%), Positives = 52/123 (42%), Gaps = 9/123 (7%) Frame = -2 Query: 541 EFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFA-----AGREEDKVAGAFSYISFGG 377 +F I +G + +R F P Y P RF G+ EDK +I FG Sbjct: 365 KFTIDEGKTLMVPLLAMHRDEKYFSEPMKYKPLRFLQTANDVGQCEDKTKSNV-FIGFGI 423 Query: 376 GRHGCLGEPFAYLQIKAIWTHLLRNFEFEL----VSPFPENDWNAMVVGIKGEVMVNYKR 209 G C+G+ FA L IK LL+NF EL V + A + K + V KR Sbjct: 424 GGSQCVGQNFAKLVIKVALIKLLQNFHLELDANQVKTLKVSHRPAPFIHTKDGLKVKLKR 483 Query: 208 RKL 200 R++ Sbjct: 484 REI 486
>CP2AD_HUMAN (Q16696) Cytochrome P450 2A13 (EC 1.14.14.1) (CYPIIA13)| Length = 494 Score = 44.7 bits (104), Expect = 2e-04 Identities = 24/85 (28%), Positives = 42/85 (49%) Frame = -2 Query: 544 KEFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHG 365 ++F + KG V R P F NP ++P F + + K + AF + F G+ Sbjct: 381 RDFFLPKGTEVFPMLGSVLRDPRFFSNPRDFNPQHFLDKKGQFKKSDAF--VPFSIGKRY 438 Query: 364 CLGEPFAYLQIKAIWTHLLRNFEFE 290 C GE A +++ +T +++NF F+ Sbjct: 439 CFGEGLARMELFLFFTTIMQNFRFK 463
>CP2A8_MESAU (P24454) Cytochrome P450 2A8 (EC 1.14.14.1) (CYPIIA8) (P450-MC1)| (P450-AFB) Length = 494 Score = 44.7 bits (104), Expect = 2e-04 Identities = 24/85 (28%), Positives = 45/85 (52%) Frame = -2 Query: 544 KEFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHG 365 ++F I KG V + + P F NP+ ++P F+ + + K + AF + F G+ Sbjct: 381 RDFLIPKGTDVFPVLSSVLKDPKFFSNPNDFNPQHFSDDKGQFKKSNAF--MPFSVGKRY 438 Query: 364 CLGEPFAYLQIKAIWTHLLRNFEFE 290 C GE A +++ +T +++NF F+ Sbjct: 439 CFGESLAKMELFIFFTTIMQNFCFK 463
>CP2A4_MOUSE (P15392) Cytochrome P450 2A4 (EC 1.14.14.1) (CYPIIA4) (Testosterone| 15-alpha-hydroxylase) (P450-15-alpha) (P450-IIA3.1) Length = 494 Score = 44.7 bits (104), Expect = 2e-04 Identities = 26/101 (25%), Positives = 48/101 (47%) Frame = -2 Query: 544 KEFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHG 365 ++F + KG V + P F NP ++P F + + K + AF + F G+ Sbjct: 381 RDFLLPKGTEVFPMLGSVLKDPKFFSNPKDFNPKHFLDDKGQFKKSDAF--VPFSIGKRY 438 Query: 364 CLGEPFAYLQIKAIWTHLLRNFEFELVSPFPENDWNAMVVG 242 C GE A +++ T++++NF F+ + D + +VG Sbjct: 439 CFGEGLARMELFLFLTNIMQNFHFKSTQAPQDIDVSPRLVG 479
>CP3AJ_CAPAE (P79152) Cytochrome P450 3A19 (EC 1.14.14.1) (CYPIIIA19) (Fragment)| Length = 218 Score = 44.7 bits (104), Expect = 2e-04 Identities = 23/80 (28%), Positives = 37/80 (46%) Frame = -2 Query: 532 IXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGE 353 I KG V + P + P+ + P+RF+ ++ + Y+ FG G C+G Sbjct: 99 IPKGTTVMVPLFVLHNNPEFWPEPEEFRPERFSKKNKDG--INPYVYLPFGTGPRNCVGM 156 Query: 352 PFAYLQIKAIWTHLLRNFEF 293 FA + IK +L+NF F Sbjct: 157 RFALMNIKLALVRILQNFSF 176
>CP2M1_ONCMY (Q92088) Cytochrome P450 2M1 (EC 1.14.14.1) (CYPIIM1) (Lauric acid| omega-6-hydroxylase) (LMC1) Length = 499 Score = 44.7 bits (104), Expect = 2e-04 Identities = 23/68 (33%), Positives = 34/68 (50%) Frame = -2 Query: 481 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 302 P +FKNPD +DP+ F K F +FG G+ C GE A +++ +T +L+ Sbjct: 404 PKLFKNPDEFDPENFLDENGVFKKNDGF--FAFGVGKRACPGEALARVELFLFFTSVLQR 461 Query: 301 FEFELVSP 278 F F P Sbjct: 462 FTFTGTKP 469
>CP4AB_HUMAN (Q02928) Cytochrome P450 4A11 precursor (EC 1.14.15.3) (CYPIVA11)| (Fatty acid omega-hydroxylase) (P-450 HK omega) (Lauric acid omega-hydroxylase) (CYP4AII) (P450-HL-omega) Length = 519 Score = 44.3 bits (103), Expect = 2e-04 Identities = 25/77 (32%), Positives = 37/77 (48%) Frame = -2 Query: 526 KGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPF 347 KG V S + P ++ NP+ +DP RFA G + A ++ F GG C+G+ F Sbjct: 407 KGIMVLLSIYGLHHNPKVWPNPEVFDPFRFAPGSAQHSHA----FLPFSGGSRNCIGKQF 462 Query: 346 AYLQIKAIWTHLLRNFE 296 A ++K L FE Sbjct: 463 AMNELKVATALTLLRFE 479
>CP17A_PANTR (Q8HYN1) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 44.3 bits (103), Expect = 2e-04 Identities = 24/85 (28%), Positives = 40/85 (47%) Frame = -2 Query: 541 EFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGC 362 EF + KG V + + + PD + P+RF ++ + SY+ FG G C Sbjct: 383 EFAVDKGTQVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSC 442 Query: 361 LGEPFAYLQIKAIWTHLLRNFEFEL 287 +GE A ++ I LL+ F+ E+ Sbjct: 443 IGEILARQELFLIMAWLLQRFDLEV 467
>CP17A_HUMAN (P05093) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-monooxygenase) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 44.3 bits (103), Expect = 2e-04 Identities = 24/85 (28%), Positives = 40/85 (47%) Frame = -2 Query: 541 EFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGC 362 EF + KG V + + + PD + P+RF ++ + SY+ FG G C Sbjct: 383 EFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSC 442 Query: 361 LGEPFAYLQIKAIWTHLLRNFEFEL 287 +GE A ++ I LL+ F+ E+ Sbjct: 443 IGEILARQELFLIMAWLLQRFDLEV 467
>CP4D8_DROME (Q9VS79) Cytochrome P450 4d8 (EC 1.14.-.-) (CYPIVD8)| Length = 463 Score = 44.3 bits (103), Expect = 2e-04 Identities = 21/65 (32%), Positives = 32/65 (49%) Frame = -2 Query: 490 NRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHL 311 +R P F NPD + P+R E F I F G C+G+ FA L++K + + Sbjct: 371 HRQPETFPNPDEFIPER----HENGSRVAPFKMIPFSAGPRNCIGQKFAQLEMKMMLAKI 426 Query: 310 LRNFE 296 +R +E Sbjct: 427 VREYE 431
>CP6B1_PAPPO (Q04552) Cytochrome P450 6B1 (EC 1.14.14.1) (CYPVIB1)| (CYP6B1V1/CYP6B1V2/ CYP6B1V3) Length = 498 Score = 44.3 bits (103), Expect = 2e-04 Identities = 33/118 (27%), Positives = 48/118 (40%), Gaps = 4/118 (3%) Frame = -2 Query: 547 GKEFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRH 368 G + I KG + S P + NP+ +DP+RF +D+ A Y+ F G Sbjct: 384 GTDITIKKGQTIIVSTWGIQNDPKYYPNPEKFDPERFNPENVKDRHPCA--YLPFSAGPR 441 Query: 367 GCLGEPFAYLQIKAIWTHLLRNFEFE----LVSPFPENDWNAMVVGIKGEVMVNYKRR 206 CLG FA Q + +L + E PF + + KG + VN RR Sbjct: 442 NCLGMRFAKWQSEVCIMKVLSKYRVEPSMKSSGPFKFDPMRLFALP-KGGIYVNLVRR 498
>C6A20_DROME (Q9V773) Probable cytochrome P450 6a20 (EC 1.14.-.-) (CYPVIA20)| Length = 501 Score = 44.3 bits (103), Expect = 2e-04 Identities = 25/86 (29%), Positives = 43/86 (50%), Gaps = 2/86 (2%) Frame = -2 Query: 541 EFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAG--AFSYISFGGGRH 368 +++I KG V + P + P+ + P+RF +ED+V A +++ FG G Sbjct: 388 KYNIEKGTGVIVPTLAIHHDPEFYPEPEKFIPERF----DEDQVQQRPACTFLPFGDGPR 443 Query: 367 GCLGEPFAYLQIKAIWTHLLRNFEFE 290 C+G F +Q+ L+ NF+FE Sbjct: 444 NCIGLRFGRMQVIVGMALLIHNFKFE 469
>CPXL_PSESP (P33006) Cytochrome P450-terp (EC 1.14.-.-) (P450terp) (Cytochrome| P450 108) Length = 428 Score = 44.3 bits (103), Expect = 2e-04 Identities = 25/76 (32%), Positives = 36/76 (47%) Frame = -2 Query: 535 DIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLG 356 +I +G + S ANR +F NPD +D RF ++ FG G H CLG Sbjct: 331 NIKRGDRIMLSYPSANRDEEVFSNPDEFDITRFPN-----------RHLGFGWGAHMCLG 379 Query: 355 EPFAYLQIKAIWTHLL 308 + A L++K + LL Sbjct: 380 QHLAKLEMKIFFEELL 395
>CP2BB_CANFA (P24460) Cytochrome P450 2B11 (EC 1.14.14.1) (CYPIIB11) (P450| PBD-2) Length = 494 Score = 44.3 bits (103), Expect = 2e-04 Identities = 31/90 (34%), Positives = 42/90 (46%) Frame = -2 Query: 532 IXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGE 353 I KG V A PH F+ PD ++PD F K AF I F G+ CLGE Sbjct: 382 IPKGTEVFPILHSALNDPHYFEKPDVFNPDHFLDANGALKKNEAF--IPFSIGKRICLGE 439 Query: 352 PFAYLQIKAIWTHLLRNFEFELVSPFPEND 263 A +++ +T +L+N F + SP D Sbjct: 440 GIARMELFLFFTTILQN--FSVASPMAPED 467
>CP2A3_RAT (P20812) Cytochrome P450 2A3 (EC 1.14.14.1) (CYPIIA3) (Coumarin| 7-hydroxylase) Length = 494 Score = 44.3 bits (103), Expect = 2e-04 Identities = 27/101 (26%), Positives = 49/101 (48%) Frame = -2 Query: 544 KEFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHG 365 +EF + KG V + P F NP+ ++P F + + K + AF + F G+ Sbjct: 381 REFLLPKGTEVFPMLGSVLKDPKFFSNPNDFNPKHFLDDKGQFKKSDAF--VPFSIGKRY 438 Query: 364 CLGEPFAYLQIKAIWTHLLRNFEFELVSPFPENDWNAMVVG 242 C GE A +++ T++++NF F+ + D + +VG Sbjct: 439 CFGEGLARMELFLFLTNIMQNFCFKSPQAPQDIDVSPRLVG 479
>CP4A5_RABIT (P14579) Cytochrome P450 4A5 precursor (EC 1.14.15.3) (CYPIVA5)| (Lauric acid omega-hydroxylase) Length = 511 Score = 44.3 bits (103), Expect = 2e-04 Identities = 23/77 (29%), Positives = 37/77 (48%) Frame = -2 Query: 526 KGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPF 347 KG V S + P+++ NP+ +DP RF G + +++ F GG C+G+ F Sbjct: 408 KGFTVTLSIYGLHHNPNVWPNPEVFDPGRFTPG----SARHSHAFLPFSGGARNCIGKQF 463 Query: 346 AYLQIKAIWTHLLRNFE 296 A ++K L FE Sbjct: 464 AMNELKVAVALTLVRFE 480
>CP6G1_DROME (Q9V674) Cytochrome P450 6g1 (EC 1.14.-.-) (CYPVIG1) (Cyp6-like| protein) Length = 524 Score = 44.3 bits (103), Expect = 2e-04 Identities = 23/60 (38%), Positives = 31/60 (51%) Frame = -2 Query: 481 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 302 P + NP +DP+RF+ ++ VA A Y FG G H C+G LQ K LL+N Sbjct: 421 PKYWTNPSQFDPERFSPANRKNIVAMA--YQPFGSGPHNCIGSRIGLLQSKLGLVSLLKN 478
>CP2CC_RAT (P11510) Cytochrome P450 2C12, female-specific (EC 1.14.14.1)| (CYPIIC12) (P450I) (15-beta) (P450-UT-I) (UT-1) Length = 490 Score = 43.9 bits (102), Expect = 3e-04 Identities = 27/98 (27%), Positives = 47/98 (47%) Frame = -2 Query: 544 KEFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHG 365 +++ I KG V TS F NP+ +DP F K + F + F G+ Sbjct: 377 RDYFIPKGTAVLTSLTSVLHARKEFPNPEMFDPGHFLDENGNFKKSDYF--MPFSAGKRK 434 Query: 364 CLGEPFAYLQIKAIWTHLLRNFEFELVSPFPENDWNAM 251 C+GE A +++ T +L+NF+ + +S + D N++ Sbjct: 435 CVGEGLASMELFLFLTTILQNFKLKSLSDPKDIDINSI 472
>CP4A7_RABIT (P14581) Cytochrome P450 4A7 precursor (EC 1.14.15.3) (CYPIVA7)| (Lauric acid omega-hydroxylase) (P450-KA-2) Length = 511 Score = 43.9 bits (102), Expect = 3e-04 Identities = 23/77 (29%), Positives = 37/77 (48%) Frame = -2 Query: 526 KGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPF 347 KG + S + P ++ NP+ +DP RFA G + +++ F GG C+G+ F Sbjct: 408 KGIIITLSIYGLHHNPKVWPNPEVFDPSRFAPG----SARHSHAFLPFSGGSRNCIGKQF 463 Query: 346 AYLQIKAIWTHLLRNFE 296 A ++K L FE Sbjct: 464 AMNELKVAVALTLVRFE 480
>CP11A_BOVIN (P00189) Cytochrome P450 11A1, mitochondrial precursor (EC| 1.14.15.6) (CYPXIA1) (P450(scc)) (Cholesterol side-chain cleavage enzyme) (Cholesterol desmolase) Length = 520 Score = 43.9 bits (102), Expect = 3e-04 Identities = 23/67 (34%), Positives = 35/67 (52%) Frame = -2 Query: 487 RLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLL 308 R P F +PD +DP R+ + +DK F + FG G C+G A L++ H+L Sbjct: 423 RDPAFFSSPDKFDPTRWLS---KDKDLIHFRNLGFGWGVRQCVGRRIAELEMTLFLIHIL 479 Query: 307 RNFEFEL 287 NF+ E+ Sbjct: 480 ENFKVEM 486
>CP52M_DEBHA (Q9Y758) Cytochrome P450 52A13 (EC 1.14.14.-) (Alkane hydroxylase| 2) (Alkane-inducible p450alk 2) (DH-ALK2) Length = 519 Score = 43.9 bits (102), Expect = 3e-04 Identities = 26/80 (32%), Positives = 42/80 (52%), Gaps = 1/80 (1%) Frame = -2 Query: 532 IXKGHXVATSXAFANRLPHIF-KNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLG 356 + KG VA S +R+ + K+ D + P+R+A R+ ++Y+ F GG CLG Sbjct: 414 VGKGTTVAYSVYSTHRMEEYYGKDADEFKPERWAESRKL-----GWAYVPFNGGPRICLG 468 Query: 355 EPFAYLQIKAIWTHLLRNFE 296 + FA + I T LL+ F+ Sbjct: 469 QQFALTEASYIVTRLLQMFD 488
>C98A3_ARATH (O22203) Cytochrome P450 98A3 (EC 1.14.-.-)| Length = 508 Score = 43.9 bits (102), Expect = 3e-04 Identities = 25/80 (31%), Positives = 38/80 (47%) Frame = -2 Query: 538 FDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCL 359 +DI KG V + R P ++KNP + P+RF + D F + FG GR C Sbjct: 381 YDIPKGSNVHVNVWAVARDPAVWKNPFEFRPERFLE-EDVDMKGHDFRLLPFGAGRRVCP 439 Query: 358 GEPFAYLQIKAIWTHLLRNF 299 G + ++ +HLL +F Sbjct: 440 GAQLGINLVTSMMSHLLHHF 459
>CP2D6_HUMAN (P10635) Cytochrome P450 2D6 (EC 1.14.14.1) (CYPIID6) (P450-DB1)| (Debrisoquine 4-hydroxylase) Length = 497 Score = 43.9 bits (102), Expect = 3e-04 Identities = 26/93 (27%), Positives = 46/93 (49%) Frame = -2 Query: 550 EGKEFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGR 371 E + F I KG + T+ + + +++ P + P+ F + AF + F GR Sbjct: 383 EVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAF--LPFSAGR 440 Query: 370 HGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFP 272 CLGEP A +++ +T LL++F F + + P Sbjct: 441 RACLGEPLARMELFLFFTSLLQHFSFSVPTGQP 473
>CP39A_HUMAN (Q9NYL5) Cytochrome P450 39A1 (EC 1.14.13.99)| (24-hydroxycholesterol 7-alpha-hydroxylase) (Oxysterol 7-alpha-hydroxylase) (hCYP39A1) Length = 469 Score = 43.5 bits (101), Expect = 4e-04 Identities = 28/112 (25%), Positives = 55/112 (49%), Gaps = 3/112 (2%) Frame = -2 Query: 532 IXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGE 353 I G + S + +R P F P+ + P+R+ E K + +++FG G+ C Sbjct: 359 IPSGDLLMLSPFWLHRNPKYFPEPELFKPERWKKANLE-KHSFLDCFMAFGSGKFQCPAR 417 Query: 352 PFAYLQIKAIWTHLLRNFEFELVSPFPENDWNAMVVGI---KGEVMVNYKRR 206 FA L+++ +L ++ L+ P P+ + +VG+ +G+ + YK+R Sbjct: 418 WFALLEVQMCIILILYKYDCSLLDPLPKQSY-LHLVGVPQPEGQCRIEYKQR 468
>CP4X1_HUMAN (Q8N118) Cytochrome P450 4X1 (EC 1.14.14.1) (CYPIVX1)| Length = 509 Score = 43.5 bits (101), Expect = 4e-04 Identities = 22/70 (31%), Positives = 38/70 (54%) Frame = -2 Query: 481 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 302 P ++KNP +DP RF+ +E ++Y+ F G C+G+ FA +++K +L + Sbjct: 417 PAVWKNPKVFDPLRFS--QENSDQRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALILLH 474 Query: 301 FEFELVSPFP 272 F V+P P Sbjct: 475 FR---VTPDP 481
>CP2D6_PANTR (Q2XNC8) Cytochrome P450 2D6 (EC 1.14.14.1) (CYPIID6)| Length = 497 Score = 43.5 bits (101), Expect = 4e-04 Identities = 26/93 (27%), Positives = 46/93 (49%) Frame = -2 Query: 550 EGKEFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGR 371 E + F I KG + T+ + + +++ P + P+ F + AF + F GR Sbjct: 383 EVQGFRIPKGTTLFTNLSSVLKDKAVWEKPFRFHPEHFLDAQGHFVKPEAF--LPFSAGR 440 Query: 370 HGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFP 272 CLGEP A +++ +T LL++F F + + P Sbjct: 441 RACLGEPLARMELFLFFTSLLQHFSFSVPTGQP 473
>CP2D6_PANPA (Q2XNC9) Cytochrome P450 2D6 (EC 1.14.14.1) (CYPIID6)| Length = 497 Score = 43.5 bits (101), Expect = 4e-04 Identities = 26/93 (27%), Positives = 46/93 (49%) Frame = -2 Query: 550 EGKEFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGR 371 E + F I KG + T+ + + +++ P + P+ F + AF + F GR Sbjct: 383 EVQGFRIPKGTTLFTNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAF--LPFSAGR 440 Query: 370 HGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFP 272 CLGEP A +++ +T LL++F F + + P Sbjct: 441 RACLGEPLARMELFLFFTSLLQHFSFSVPTGQP 473
>CP2A6_HUMAN (P11509) Cytochrome P450 2A6 (EC 1.14.14.1) (CYPIIA6) (Coumarin| 7-hydroxylase) (P450 IIA3) (CYP2A3) (P450(I)) Length = 494 Score = 43.5 bits (101), Expect = 4e-04 Identities = 23/85 (27%), Positives = 41/85 (48%) Frame = -2 Query: 544 KEFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHG 365 ++F + KG V R P F NP ++P F + + K + AF + F G+ Sbjct: 381 RDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQHFLNEKGQFKKSDAF--VPFSIGKRN 438 Query: 364 CLGEPFAYLQIKAIWTHLLRNFEFE 290 C GE A +++ +T +++NF + Sbjct: 439 CFGEGLARMELFLFFTTVMQNFRLK 463
>CP2A5_MOUSE (P20852) Cytochrome P450 2A5 (EC 1.14.14.1) (CYPIIA5) (Coumarin| 7-hydroxylase) (P450-15-COH) (P450-IIA3.2) Length = 494 Score = 43.5 bits (101), Expect = 4e-04 Identities = 26/101 (25%), Positives = 47/101 (46%) Frame = -2 Query: 544 KEFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHG 365 ++F + KG V + P F NP ++P F + + K AF + F G+ Sbjct: 381 RDFLLPKGTEVFPMLGSVLKDPKFFSNPKDFNPKHFLDDKGQFKKNDAF--VPFSIGKRY 438 Query: 364 CLGEPFAYLQIKAIWTHLLRNFEFELVSPFPENDWNAMVVG 242 C GE A +++ T++++NF F+ + D + +VG Sbjct: 439 CFGEGLARMELFLFLTNIMQNFHFKSTQAPQDIDVSPRLVG 479
>CP6V1_DROME (Q9VRB3) Probable cytochrome P450 6v1 (EC 1.14.-.-) (CYPVIV1)| Length = 520 Score = 43.5 bits (101), Expect = 4e-04 Identities = 24/80 (30%), Positives = 37/80 (46%) Frame = -2 Query: 526 KGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPF 347 +G V S + P + +PD +DP+RF+A + + SY+ FG G C+G Sbjct: 413 RGMPVFISNLAIHHDPKYWPDPDRFDPERFSAANKA--LQAPMSYMPFGAGPRNCIGMQI 470 Query: 346 AYLQIKAIWTHLLRNFEFEL 287 LQIK + L E+ Sbjct: 471 GLLQIKLGLVYFLHQHRVEI 490
>C340_ORYLA (Q98T91) Cytochrome P450 3A40 (EC 1.14.14.1)| Length = 502 Score = 43.5 bits (101), Expect = 4e-04 Identities = 18/68 (26%), Positives = 37/68 (54%) Frame = -2 Query: 490 NRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHL 311 +R P ++ P+ + P+RF+ +E ++Y+ FG G C+G FA + +K + Sbjct: 403 HRDPELWPEPEKFKPERFS--KENKDTFDPYTYMPFGAGPRNCIGMRFALVMMKLAVVEI 460 Query: 310 LRNFEFEL 287 L+ ++F + Sbjct: 461 LQTYDFSV 468
>CP3AF_CAVPO (Q64406) Cytochrome P450 3A15 (EC 1.14.14.1) (CYPIIIA15)| Length = 503 Score = 43.5 bits (101), Expect = 4e-04 Identities = 26/89 (29%), Positives = 41/89 (46%), Gaps = 5/89 (5%) Frame = -2 Query: 544 KEFDIX-----KGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFG 380 K+F+I KG V +R + PD + P+RF+ +E+ + Y+ FG Sbjct: 379 KDFEINGMSFPKGTLVMIPSFALHRDSKYWPEPDEFRPERFSKKNKEN--IDPYIYMPFG 436 Query: 379 GGRHGCLGEPFAYLQIKAIWTHLLRNFEF 293 G C+G A + +K LL+NF F Sbjct: 437 NGPRNCIGRRMALMNLKLALIRLLQNFSF 465
>CP6L1_BLAGE (Q9GQM9) Cytochrome P450 6l1 (EC 1.14.-.-) (CYPVIL1)| Length = 503 Score = 43.1 bits (100), Expect = 6e-04 Identities = 24/86 (27%), Positives = 41/86 (47%) Frame = -2 Query: 547 GKEFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRH 368 G + I KG + S +R + +P+ ++P+RF +E+ FSYI FG G Sbjct: 379 GTDVVIEKGTPIFVSLLGLHRDSIFYPDPEDFNPERF--NKEKKSGVHPFSYIPFGDGPR 436 Query: 367 GCLGEPFAYLQIKAIWTHLLRNFEFE 290 C+G + +K + LL++ E Sbjct: 437 NCIGLRLGLMSVKLVIIMLLQSLRVE 462
>C77A3_SOYBN (O48928) Cytochrome P450 77A3 (EC 1.14.-.-)| Length = 513 Score = 43.1 bits (100), Expect = 6e-04 Identities = 23/76 (30%), Positives = 38/76 (50%), Gaps = 2/76 (2%) Frame = -2 Query: 481 PHIFKNPDSYDPDRFAAGREEDKVAG--AFSYISFGGGRHGCLGEPFAYLQIKAIWTHLL 308 P + NP+ +DP+RF +G EE + G + FG GR C G A + I + ++ Sbjct: 410 PKNWLNPEKFDPERFISGGEEADITGVTGVKMMPFGVGRRICPGLAMATVHIHLMMARMV 469 Query: 307 RNFEFELVSPFPENDW 260 + FE+ P + D+ Sbjct: 470 QEFEWGAYPPEKKMDF 485
>CP2S1_HUMAN (Q96SQ9) Cytochrome P450 2S1 (EC 1.14.14.1) (CYPIIS1)| Length = 504 Score = 43.1 bits (100), Expect = 6e-04 Identities = 27/72 (37%), Positives = 40/72 (55%), Gaps = 2/72 (2%) Frame = -2 Query: 481 PHIFKNPDSYDPDRF--AAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLL 308 P+IFK+P+ ++PDRF A GR A ++ F G+ CLGE A ++ +T +L Sbjct: 403 PNIFKHPEEFNPDRFLDADGRFRKHEA----FLPFSLGKRVCLGEGLAKAELFLFFTTIL 458 Query: 307 RNFEFELVSPFP 272 + F E SP P Sbjct: 459 QAFSLE--SPCP 468
>CP2CD_RAT (P20814) Cytochrome P450 2C13, male-specific (EC 1.14.14.1)| (CYPIIC13) (P450-G) (P-450g) (UT-5) Length = 490 Score = 43.1 bits (100), Expect = 6e-04 Identities = 29/90 (32%), Positives = 42/90 (46%), Gaps = 1/90 (1%) Frame = -2 Query: 544 KEFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHG 365 + + I KG V TS F NP+ +DP F K + F I F G+ Sbjct: 377 RNYFIPKGTAVLTSLTSVLHDSKEFPNPEMFDPGHFLDENGNFKKSDYF--IPFSAGKRM 434 Query: 364 CLGEPFAYLQIKAIWTHLLRNFEFE-LVSP 278 CLGE A +++ T +L+NF+ + LV P Sbjct: 435 CLGESLARMELFLFLTTILQNFKLKSLVDP 464
>CP17A_MESAU (P70687) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 511 Score = 43.1 bits (100), Expect = 6e-04 Identities = 23/85 (27%), Positives = 38/85 (44%) Frame = -2 Query: 541 EFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGC 362 EF I K V + + + PD + P+RF + + SY+ FG G C Sbjct: 383 EFSIPKFTPVIINLWALHHSEKEWDQPDRFMPERFLDPTGSHLITPSLSYLPFGAGARSC 442 Query: 361 LGEPFAYLQIKAIWTHLLRNFEFEL 287 +GE A ++ HLL+ F+ ++ Sbjct: 443 IGEVLARQELFLFMAHLLQRFDLDV 467
>C76C1_ARATH (O64636) Cytochrome P450 76C1 (EC 1.14.-.-)| Length = 512 Score = 43.1 bits (100), Expect = 6e-04 Identities = 24/84 (28%), Positives = 40/84 (47%) Frame = -2 Query: 538 FDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCL 359 F + K V + R P ++ NP ++P+RF G++ D + FG GR C Sbjct: 393 FMVLKDTQVLVNVWAIGRDPSVWDNPSQFEPERFL-GKDMDVRGRDYELTPFGAGRRICP 451 Query: 358 GEPFAYLQIKAIWTHLLRNFEFEL 287 G P A + + LL +F+++L Sbjct: 452 GMPLAMKTVSLMLASLLYSFDWKL 475
>C75A3_PETHY (P48419) Flavonoid 3',5'-hydroxylase 2 (EC 1.14.13.88) (F3'5'H)| (Cytochrome P450 75A3) (CYPLXXVA3) Length = 508 Score = 43.1 bits (100), Expect = 6e-04 Identities = 23/71 (32%), Positives = 37/71 (52%), Gaps = 2/71 (2%) Frame = -2 Query: 487 RLPHIFKNPDSYDPDRFAAGREE--DKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTH 314 R P +++NP + P+RF +GR D F I FG GR C G + ++ I Sbjct: 400 RDPEVWENPLEFYPERFLSGRNSKIDPRGNDFELIPFGAGRRICAGTRMGIVMVEYILGT 459 Query: 313 LLRNFEFELVS 281 L+ +F+++L S Sbjct: 460 LVHSFDWKLPS 470
>CP6A1_MUSDO (P13527) Cytochrome P450 6A1 (EC 1.14.14.1) (CYPVIA1)| Length = 509 Score = 43.1 bits (100), Expect = 6e-04 Identities = 20/67 (29%), Positives = 36/67 (53%) Frame = -2 Query: 481 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 302 P ++ NP+ +DP+RF+ E K + ++ FG G C+G F +Q + ++R+ Sbjct: 412 PELYPNPEEFDPERFSP--EMVKQRDSVDWLGFGDGPRNCIGMRFGKMQSRLGLALVIRH 469 Query: 301 FEFELVS 281 F F + S Sbjct: 470 FRFTVCS 476
>C13A8_CAEEL (Q27516) Putative cytochrome P450 CYP13A8 (EC 1.14.-.-)| Length = 509 Score = 43.1 bits (100), Expect = 6e-04 Identities = 22/63 (34%), Positives = 33/63 (52%) Frame = -2 Query: 478 HIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNF 299 H KN D + F R + + +Y+SFG G CLG FA L+ K + +H+L+ + Sbjct: 417 HHDKNVWGNDVEEFKPERWDSPLTPQQAYLSFGAGPRVCLGMRFALLEQKGLLSHILKKY 476 Query: 298 EFE 290 FE Sbjct: 477 TFE 479
>CP2DP_PIG (O46658) Cytochrome P450 2D25 (EC 1.14.14.-) (CYPIID25) (Vitamin| D(3) 25-hydroxylase) Length = 499 Score = 43.1 bits (100), Expect = 6e-04 Identities = 29/95 (30%), Positives = 47/95 (49%), Gaps = 2/95 (2%) Frame = -2 Query: 550 EGKEFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRF--AAGREEDKVAGAFSYISFGG 377 E + F I KG + T+ + ++K P + P+ F A GR + A ++ F Sbjct: 385 EVQGFLIPKGTTLITNLTSVLKDETVWKKPFRFYPEHFLDAQGRFTKQEA----FMPFSA 440 Query: 376 GRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFP 272 GR CLGEP A +++ +T LL+ F F + + P Sbjct: 441 GRRSCLGEPLARMELFLFFTTLLQAFSFSVPTGQP 475
>CP2CL_CANFA (P56594) Cytochrome P450 2C21 (EC 1.14.14.1) (CYPIIC21) (DM1-1)| (Fragment) Length = 487 Score = 43.1 bits (100), Expect = 6e-04 Identities = 27/90 (30%), Positives = 45/90 (50%), Gaps = 1/90 (1%) Frame = -2 Query: 544 KEFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHG 365 +E+ I KG + TS F NPD +DP F K + F ++F G+ Sbjct: 374 REYLIPKGTTILTSLTSVLHDEKGFPNPDQFDPGHFLDENGSFKKSDYF--MAFSAGKRV 431 Query: 364 CLGEPFAYLQIKAIWTHLLRNFEFE-LVSP 278 C+GE A +++ + T++L++F + LV P Sbjct: 432 CVGEGLARMELFLLLTNILQHFTLKPLVDP 461
>CP4FC_HUMAN (Q9HCS2) Cytochrome P450 4F12 (EC 1.14.14.1) (CYPIVF12)| Length = 524 Score = 42.7 bits (99), Expect = 7e-04 Identities = 20/63 (31%), Positives = 33/63 (52%) Frame = -2 Query: 481 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 302 P ++ +P+ YDP RF E K ++I F G C+G+ FA ++K + +L + Sbjct: 431 PTVWPDPEVYDPFRFDP--ENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLH 488 Query: 301 FEF 293 F F Sbjct: 489 FRF 491
>C75A4_GENTR (Q96581) Flavonoid 3',5'-hydroxylase (EC 1.14.13.88) (F3'5'H)| (Cytochrome P450 75A4) Length = 516 Score = 42.7 bits (99), Expect = 7e-04 Identities = 30/95 (31%), Positives = 46/95 (48%), Gaps = 3/95 (3%) Frame = -2 Query: 532 IXKGHXVATSXAFANRLPHIF-KNPDSYDPDRFAAGREE--DKVAGAFSYISFGGGRHGC 362 I KG + + R P ++ NP+ +DP+RF GR D F I FG GR C Sbjct: 394 IPKGTRLNVNIWAIGRDPSVWGDNPNEFDPERFLYGRNAKIDPRGNHFELIPFGAGRRIC 453 Query: 361 LGEPFAYLQIKAIWTHLLRNFEFELVSPFPENDWN 257 G L ++ I L+ +F+++L F E++ N Sbjct: 454 AGTRMGILLVEYILGTLVHSFDWKL--GFSEDELN 486
>CP3AH_CAVPO (Q64409) Cytochrome P450 3A17 (EC 1.14.14.1) (CYPIIIA17)| Length = 503 Score = 42.7 bits (99), Expect = 7e-04 Identities = 26/89 (29%), Positives = 41/89 (46%), Gaps = 5/89 (5%) Frame = -2 Query: 544 KEFDIX-----KGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFG 380 K+F+I KG V +R + PD + P+RF+ +E+ + Y+ FG Sbjct: 379 KDFEINGMSFPKGTGVMIPSFALHRDSKYWPEPDEFRPERFSKKNKEN--IDPYIYMPFG 436 Query: 379 GGRHGCLGEPFAYLQIKAIWTHLLRNFEF 293 G C+G A + +K LL+NF F Sbjct: 437 NGPRNCIGMRMALMNLKLALIRLLQNFSF 465
>CP3AE_CAVPO (Q64417) Cytochrome P450 3A14 (EC 1.14.14.1) (CYPIIIA14)| Length = 503 Score = 42.7 bits (99), Expect = 7e-04 Identities = 26/89 (29%), Positives = 41/89 (46%), Gaps = 5/89 (5%) Frame = -2 Query: 544 KEFDIX-----KGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFG 380 K+F+I KG V +R + PD + P+RF+ +E+ + Y+ FG Sbjct: 379 KDFEINGMSFPKGTGVMIPSFALHRDSKYWPEPDEFRPERFSKKNKEN--IDPYIYMPFG 436 Query: 379 GGRHGCLGEPFAYLQIKAIWTHLLRNFEF 293 G C+G A + +K LL+NF F Sbjct: 437 NGPRNCIGMRMALMNLKLALIRLLQNFSF 465
>CP3AD_MOUSE (Q64464) Cytochrome P450 3A13 (EC 1.14.14.1) (CYPIIIA13)| Length = 503 Score = 42.7 bits (99), Expect = 7e-04 Identities = 22/78 (28%), Positives = 39/78 (50%) Frame = -2 Query: 532 IXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGE 353 I KG V ++ P + P+ + P+RF+ + +D + + Y+ FG G C+G Sbjct: 388 IPKGTVVMIPTFALHKDPKYWPEPEEFRPERFSK-KNQDSI-NPYMYLPFGSGPRNCIGM 445 Query: 352 PFAYLQIKAIWTHLLRNF 299 FA + +K +L+NF Sbjct: 446 RFALINMKVALVRVLQNF 463
>CP3AA_MESAU (Q64148) Cytochrome P450 3A10 (EC 1.14.13.94) (CYPIIIA10)| (Lithocholate 6-beta-hydroxylase) (6 beta-hydroxylase) Length = 503 Score = 42.7 bits (99), Expect = 7e-04 Identities = 24/81 (29%), Positives = 38/81 (46%) Frame = -2 Query: 532 IXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGE 353 I KG V +R P + P+ + P+RF+ +E + Y+ FG G C+G Sbjct: 388 IPKGITVMVPTYPLHRDPEYWPEPEEFRPERFS--KENKGSIDPYVYMPFGNGPRNCIGM 445 Query: 352 PFAYLQIKAIWTHLLRNFEFE 290 FA L +K +L+NF + Sbjct: 446 RFALLSMKLAVVSVLQNFTLQ 466
>CP3A3_HUMAN (P05184) Cytochrome P450 3A3 (EC 1.14.14.1) (CYPIIIA3) (HLp)| Length = 503 Score = 42.7 bits (99), Expect = 7e-04 Identities = 23/81 (28%), Positives = 39/81 (48%) Frame = -2 Query: 532 IXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGE 353 I KG V +R P + P+ + P+RF+ +++ + Y FG G C+G Sbjct: 388 IPKGWVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDN--IDPYIYTPFGSGPRNCIGM 445 Query: 352 PFAYLQIKAIWTHLLRNFEFE 290 FA + +K +L+NF F+ Sbjct: 446 RFALMNMKLALIRVLQNFSFK 466
>C11B1_SHEEP (P51663) Cytochrome P450 11B1, mitochondrial precursor (EC| 1.14.15.4) (CYPXIB1) (P450C11) (Steroid 11-beta-hydroxylase) Length = 503 Score = 42.7 bits (99), Expect = 7e-04 Identities = 24/88 (27%), Positives = 41/88 (46%) Frame = -2 Query: 544 KEFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHG 365 + + I G V R P +F P+SY P R+ + F +++FG G Sbjct: 393 QNYHIPAGTLVKVLLYSLGRNPAVFARPESYHPQRWL---DRQGSGSRFPHLAFGFGMRQ 449 Query: 364 CLGEPFAYLQIKAIWTHLLRNFEFELVS 281 CLG A +++ + H+L+NF E ++ Sbjct: 450 CLGRRVAEVEMLLLLHHVLKNFLVETLA 477
>CP238_MOUSE (P56655) Cytochrome P450 2C38 (EC 1.14.14.1) (CYPIIC38)| Length = 490 Score = 42.7 bits (99), Expect = 7e-04 Identities = 28/90 (31%), Positives = 43/90 (47%), Gaps = 1/90 (1%) Frame = -2 Query: 544 KEFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHG 365 + + I KG V TS F NP+ +DP F K + F ++F G+ Sbjct: 377 RNYIIPKGTTVVTSLTSVLHDSKEFPNPEMFDPGHFLDANGNFKKSDYF--MTFSAGKRV 434 Query: 364 CLGEPFAYLQIKAIWTHLLRNFEFE-LVSP 278 C GE A +++ I T +L+NF+ + LV P Sbjct: 435 CAGEGLARMELFLILTTILQNFKLKSLVHP 464
>CP4AE_MOUSE (O35728) Cytochrome P450 4A14 precursor (EC 1.14.15.3) (CYPIVA14)| (Lauric acid omega-hydroxylase 3) (P450-LA-omega 3) Length = 507 Score = 42.7 bits (99), Expect = 7e-04 Identities = 25/79 (31%), Positives = 35/79 (44%) Frame = -2 Query: 532 IXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGE 353 I KG S + P + NP +DP RFA D + +Y+ F GG C+G+ Sbjct: 402 IPKGITATISIYGLHHNPRFWPNPKVFDPSRFAP----DSSHHSHAYLPFSGGSRNCIGK 457 Query: 352 PFAYLQIKAIWTHLLRNFE 296 FA ++K L FE Sbjct: 458 QFAMNELKVAVALTLLRFE 476
>CP2A7_HUMAN (P20853) Cytochrome P450 2A7 (EC 1.14.14.1) (CYPIIA7) (P450-IIA4)| Length = 494 Score = 42.7 bits (99), Expect = 7e-04 Identities = 23/85 (27%), Positives = 41/85 (48%) Frame = -2 Query: 544 KEFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHG 365 ++F + KG V R P F NP ++P F + + K + AF + F G+ Sbjct: 381 RDFFLPKGTEVFPMLGSVLRDPSFFSNPQDFNPQHFLDDKGQFKKSDAF--VPFSIGKRY 438 Query: 364 CLGEPFAYLQIKAIWTHLLRNFEFE 290 C GE A +++ +T +++NF + Sbjct: 439 CFGEGLARMELFLFFTTVMQNFRLK 463
>CP21A_CANFA (Q8WNW0) Cytochrome P450 21 (EC 1.14.99.10) (Cytochrome P450 XXI)| (Steroid 21-hydroxylase) (21-OHase) (P450-C21) (P-450c21) Length = 492 Score = 42.7 bits (99), Expect = 7e-04 Identities = 25/80 (31%), Positives = 39/80 (48%) Frame = -2 Query: 538 FDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCL 359 +DI +G V + A+ +++ P + PDRF +V ++FG G CL Sbjct: 374 YDIPEGMVVIPNLQGAHLDETVWERPQEFRPDRFLVPGASPRV------LAFGCGARVCL 427 Query: 358 GEPFAYLQIKAIWTHLLRNF 299 GEP A L++ + LLR F Sbjct: 428 GEPLARLELLVVLAQLLRAF 447
>CP131_DROME (Q9VFJ0) Probable cytochrome P450 313a1 (EC 1.14.-.-)| (CYPCCCXIIIA1) Length = 492 Score = 42.7 bits (99), Expect = 7e-04 Identities = 23/80 (28%), Positives = 40/80 (50%), Gaps = 1/80 (1%) Frame = -2 Query: 532 IXKGHXVATSXAFANRLPHIF-KNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLG 356 I KG + +R P ++ + D+++PD F A E K ++YI F G+ C+G Sbjct: 383 IPKGVVIGIDMFHTHRNPEVWGPDADNFNPDNFLAENMEQK--HPYAYIPFARGKRNCIG 440 Query: 355 EPFAYLQIKAIWTHLLRNFE 296 +A + K +LRN++ Sbjct: 441 SKYAMMSSKFALCRILRNYK 460
>CPXG_STRSQ (P23296) Cytochrome P450 105C1 (EC 1.14.-.-)| Length = 381 Score = 42.7 bits (99), Expect = 7e-04 Identities = 25/78 (32%), Positives = 35/78 (44%) Frame = -2 Query: 532 IXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGE 353 + G V S ANR P F+ PD+ D R G +++FG G H CLG Sbjct: 285 VKAGEVVVVSLGAANRDPARFERPDAVDVTREDTG-----------HLAFGHGMHQCLGR 333 Query: 352 PFAYLQIKAIWTHLLRNF 299 A ++++ T LL F Sbjct: 334 QLARIELRVALTALLERF 351
>CP3A4_HUMAN (P08684) Cytochrome P450 3A4 (EC 1.14.13.67) (Quinine| 3-monooxygenase) (CYPIIIA4) (Nifedipine oxidase) (Taurochenodeoxycholate 6-alpha-hydroxylase) (EC 1.14.13.97) (NF-25) (P450-PCN1) Length = 502 Score = 42.7 bits (99), Expect = 7e-04 Identities = 23/81 (28%), Positives = 39/81 (48%) Frame = -2 Query: 532 IXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGE 353 I KG V +R P + P+ + P+RF+ +++ + Y FG G C+G Sbjct: 387 IPKGWVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDN--IDPYIYTPFGSGPRNCIGM 444 Query: 352 PFAYLQIKAIWTHLLRNFEFE 290 FA + +K +L+NF F+ Sbjct: 445 RFALMNMKLALIRVLQNFSFK 465
>CP17A_CAVPO (Q64410) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 42.7 bits (99), Expect = 7e-04 Identities = 25/85 (29%), Positives = 38/85 (44%) Frame = -2 Query: 541 EFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGC 362 EF I K V + + + PD + P+RF + + SY+ FG G C Sbjct: 383 EFAIDKDTNVLVNLWALHHNEQEWDRPDQFMPERFLDPTGSQIIVPSSSYLPFGAGPRSC 442 Query: 361 LGEPFAYLQIKAIWTHLLRNFEFEL 287 +GE A +I I LL+ F+ E+ Sbjct: 443 VGEALARQEIFLITAWLLQKFDLEV 467
>CP270_RAT (P19225) Cytochrome P450 2C70 (EC 1.14.14.1) (CYPIIC70) (P-450Md)| (P450 P49) Length = 489 Score = 42.7 bits (99), Expect = 7e-04 Identities = 28/92 (30%), Positives = 45/92 (48%), Gaps = 1/92 (1%) Frame = -2 Query: 550 EGKEFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGR 371 E + + I KG V A F NP+ +DP F + K + F ++F GR Sbjct: 374 EFRGYHIPKGTSVMACLTSALHDDKEFPNPEKFDPGHFLDEKGNFKKSDYF--MAFSAGR 431 Query: 370 HGCLGEPFAYLQIKAIWTHLLRNFEFE-LVSP 278 C+GE A +++ I T +L++F + LV+P Sbjct: 432 RACIGEGLARMEMFLILTSILQHFTLKPLVNP 463
>CP17A_BOVIN (P05185) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 509 Score = 42.7 bits (99), Expect = 7e-04 Identities = 22/85 (25%), Positives = 40/85 (47%) Frame = -2 Query: 541 EFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGC 362 + I KG V + + +++PD + P+RF ++ + SY+ FG G C Sbjct: 383 DLTIDKGTDVVVNLWALHHSEKEWQHPDLFMPERFLDPTGTQLISPSLSYLPFGAGPRSC 442 Query: 361 LGEPFAYLQIKAIWTHLLRNFEFEL 287 +GE A ++ + LL+ F E+ Sbjct: 443 VGEMLARQELFLFMSRLLQRFNLEI 467
>CP17A_BISBI (Q9GMC7) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 509 Score = 42.7 bits (99), Expect = 7e-04 Identities = 22/85 (25%), Positives = 40/85 (47%) Frame = -2 Query: 541 EFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGC 362 + I KG V + + +++PD + P+RF ++ + SY+ FG G C Sbjct: 383 DLTIDKGTDVVVNLWALHHSEKEWQHPDLFMPERFLDPTGTQLISPSLSYLPFGAGPRSC 442 Query: 361 LGEPFAYLQIKAIWTHLLRNFEFEL 287 +GE A ++ + LL+ F E+ Sbjct: 443 VGEMLARQELFLFMSRLLQRFNLEI 467
>CP3AI_RAT (Q64581) Cytochrome P450 3A18 (EC 1.14.14.1) (CYPIIIA18)| (P450(6)beta-2) Length = 497 Score = 42.7 bits (99), Expect = 7e-04 Identities = 23/81 (28%), Positives = 39/81 (48%) Frame = -2 Query: 532 IXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGE 353 I KG V +R P + P+ ++P+RF+ +E + Y+ FG G C+G Sbjct: 388 IPKGTVVTIPIYPLHRNPEYWLEPEEFNPERFS--KENKGSIDPYVYLPFGNGPRNCIGM 445 Query: 352 PFAYLQIKAIWTHLLRNFEFE 290 FA + +K +L+NF + Sbjct: 446 RFALISMKLAVIGVLQNFNIQ 466
>CP270_MOUSE (Q91W64) Cytochrome P450 2C70 (EC 1.14.14.1) (CYPIIC70)| Length = 489 Score = 42.4 bits (98), Expect = 0.001 Identities = 27/92 (29%), Positives = 44/92 (47%), Gaps = 1/92 (1%) Frame = -2 Query: 550 EGKEFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGR 371 E + + I KG V F NP+ +DP F + K + F ++F GR Sbjct: 374 EFRGYHIPKGTSVMACLTSVLNDDKEFPNPEKFDPGHFLDEKGNFKKSDYF--VAFSAGR 431 Query: 370 HGCLGEPFAYLQIKAIWTHLLRNFEFE-LVSP 278 C+GE A +++ I T++L++F + LV P Sbjct: 432 RACIGEGLARMEMFLILTNILQHFTLKPLVKP 463
>C6A21_DROME (Q9V774) Probable cytochrome P450 6a21 (EC 1.14.-.-) (CYPVIA21)| Length = 504 Score = 42.4 bits (98), Expect = 0.001 Identities = 21/85 (24%), Positives = 45/85 (52%) Frame = -2 Query: 541 EFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGC 362 ++ I KG V +R ++ NP++++PD F+ R +++ + ++ FG G C Sbjct: 392 KYVIKKGMPVLIPCGAMHRDEKLYANPNTFNPDNFSPERVKER--DSVEWLPFGDGPRNC 449 Query: 361 LGEPFAYLQIKAIWTHLLRNFEFEL 287 +G F +Q + L+++F+F + Sbjct: 450 IGMRFGQMQARIGLALLIKDFKFSV 474
>C71A4_SOLME (P37117) Cytochrome P450 71A4 (EC 1.14.-.-) (CYPLXXIA4) (P-450EG2)| Length = 507 Score = 42.4 bits (98), Expect = 0.001 Identities = 27/83 (32%), Positives = 37/83 (44%), Gaps = 5/83 (6%) Frame = -2 Query: 520 HXVATSXAFAN-----RLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLG 356 H A + A N R P ++NP+ + P+RF + D F + FG GR GC G Sbjct: 392 HIPARTQALINVWAIGRDPLSWENPEEFCPERFL-NNDIDMKGLKFELLPFGSGRRGCPG 450 Query: 355 EPFAYLQIKAIWTHLLRNFEFEL 287 FA I+ L+ F F L Sbjct: 451 SSFAIAVIELALARLVHKFNFAL 473
>CP2J2_HUMAN (P51589) Cytochrome P450 2J2 (EC 1.14.14.1) (CYPIIJ2) (Arachidonic| acid epoxygenase) Length = 502 Score = 42.4 bits (98), Expect = 0.001 Identities = 22/82 (26%), Positives = 41/82 (50%) Frame = -2 Query: 538 FDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCL 359 + + KG + T+ +R P + PD+++PD F E + +++ F G+ CL Sbjct: 393 YHLPKGTMILTNLTALHRDPTEWATPDTFNPDHFL---ENGQFKKREAFMPFSIGKRACL 449 Query: 358 GEPFAYLQIKAIWTHLLRNFEF 293 GE A ++ +T L++ F F Sbjct: 450 GEQLARTELFIFFTSLMQKFTF 471
>CP343_HUMAN (Q9HB55) Cytochrome P450 3A43 (EC 1.14.14.1)| Length = 503 Score = 42.4 bits (98), Expect = 0.001 Identities = 25/81 (30%), Positives = 38/81 (46%) Frame = -2 Query: 532 IXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGE 353 I KG V + P + P+ + P+RF+ + +D + + YI FG G C+G Sbjct: 388 IPKGLAVMVPIYALHHDPKYWTEPEKFCPERFSK-KNKDSI-DLYRYIPFGAGPRNCIGM 445 Query: 352 PFAYLQIKAIWTHLLRNFEFE 290 FA IK L+NF F+ Sbjct: 446 RFALTNIKLAVIRALQNFSFK 466
>CP3A7_HUMAN (P24462) Cytochrome P450 3A7 (EC 1.14.14.1) (CYPIIIA7) (P450-HFLA)| Length = 503 Score = 42.0 bits (97), Expect = 0.001 Identities = 22/81 (27%), Positives = 39/81 (48%) Frame = -2 Query: 532 IXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGE 353 I KG V + P ++ P+ + P+RF+ +++ + Y FG G C+G Sbjct: 388 IPKGVVVMIPSYVLHHDPKYWREPEKFLPERFSKKNKDN--IDPYIYTPFGSGPRNCIGM 445 Query: 352 PFAYLQIKAIWTHLLRNFEFE 290 FA + +K +L+NF F+ Sbjct: 446 RFALVNMKLALVRVLQNFSFK 466
>CP11A_RAT (P14137) Cytochrome P450 11A1, mitochondrial precursor (EC| 1.14.15.6) (CYPXIA1) (P450(scc)) (Cholesterol side-chain cleavage enzyme) (Cholesterol desmolase) Length = 526 Score = 42.0 bits (97), Expect = 0.001 Identities = 22/64 (34%), Positives = 33/64 (51%) Frame = -2 Query: 472 FKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEF 293 F NP+ +DP R+ E+ + F Y+ FG G CLG A L++ ++L NF Sbjct: 426 FPNPNKFDPTRWL---EKSQNTTHFRYLGFGWGVRQCLGRRIAELEMTIFLINVLENFRI 482 Query: 292 ELVS 281 E+ S Sbjct: 483 EVQS 486
>CP4A4_RABIT (P10611) Cytochrome P450 4A4 precursor (EC 1.14.14.1) (CYPIVA4)| (Prostaglandin omega-hydroxylase) (P450-P-2) Length = 510 Score = 42.0 bits (97), Expect = 0.001 Identities = 20/62 (32%), Positives = 33/62 (53%) Frame = -2 Query: 481 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 302 P +++NP+ +DP RFA D + +++ F GG C+G+ FA ++K L Sbjct: 422 PKVWQNPEVFDPFRFAP----DSAYHSHAFLPFSGGARNCIGKQFAMRELKVAVALTLVR 477 Query: 301 FE 296 FE Sbjct: 478 FE 479
>CP391_DROME (Q9VQD2) Probable cytochrome P450 309a1 (EC 1.14.-.-) (CYPCCCIXA1)| Length = 529 Score = 42.0 bits (97), Expect = 0.001 Identities = 27/114 (23%), Positives = 46/114 (40%) Frame = -2 Query: 550 EGKEFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGR 371 + K D+ G V + I+ + PDRF G + ++ FG G Sbjct: 414 DDKTLDLEPGVTVMVPAYQYHHDNDIYPEASEFRPDRFENGAAS-VLTKRGCFLPFGDGP 472 Query: 370 HGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFPENDWNAMVVGIKGEVMVNYKR 209 CLG L +K H+L N++ E + P + M + + G+V + Y + Sbjct: 473 RICLGMRVGQLSVKTAIVHILSNYQVEQMKKVPLGADSGMGIFLNGDVELKYTK 526
>CP6A9_DROME (Q27594) Cytochrome P450 6a9 (EC 1.14.-.-) (CYPVIA9)| Length = 504 Score = 42.0 bits (97), Expect = 0.001 Identities = 21/85 (24%), Positives = 44/85 (51%) Frame = -2 Query: 541 EFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGC 362 ++ I KG V +R ++ NP++++PD F+ R +++ + ++ FG G C Sbjct: 392 KYVIKKGMPVLIPCGAMHRDEKLYANPNTFNPDNFSPERVKER--DSVEWLPFGDGPRNC 449 Query: 361 LGEPFAYLQIKAIWTHLLRNFEFEL 287 +G F +Q ++ L+ F+F + Sbjct: 450 IGMRFGQMQARSGLALLINRFKFSV 474
>CPS2_STRCC (Q59831) Cytochrome P450 105A3 (EC 1.14.-.-) (Cytochrome P450| sca-2) (CYT P-450sca-2) Length = 409 Score = 42.0 bits (97), Expect = 0.001 Identities = 26/74 (35%), Positives = 36/74 (48%) Frame = -2 Query: 532 IXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGE 353 I G V + + ANR +F+NPD D R A ++SFG G H CLG+ Sbjct: 313 IRAGEGVIVTNSIANRDSSVFENPDRLDVHRSAR-----------HHLSFGYGVHQCLGQ 361 Query: 352 PFAYLQIKAIWTHL 311 A L+++ I T L Sbjct: 362 NLARLELEVILTVL 375
>CP6D3_MUSDO (Q964Q7) Cytochrome P450 6d3 (EC 1.14.-.-) (CYPVID3) (Pyrethroid| resistance cytochrome P450) Length = 520 Score = 42.0 bits (97), Expect = 0.001 Identities = 28/93 (30%), Positives = 40/93 (43%) Frame = -2 Query: 541 EFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGC 362 +F I K V S +R F P +Y P+RFA +E K A +Y+ FG G C Sbjct: 405 KFTIKKDTNVIISLLGLHRDAKYFPEPLAYKPERFA---DETKDYDAAAYMPFGEGPRHC 461 Query: 361 LGEPFAYLQIKAIWTHLLRNFEFELVSPFPEND 263 + + + K +L NF E P P + Sbjct: 462 IAQRMGVMNTKVALAKILANFNIE---PMPHKE 491
>CP11A_HORSE (O46515) Cytochrome P450 11A1, mitochondrial precursor (EC| 1.14.15.6) (CYPXIA1) (P450(scc)) (Cholesterol side-chain cleavage enzyme) (Cholesterol desmolase) Length = 520 Score = 42.0 bits (97), Expect = 0.001 Identities = 22/65 (33%), Positives = 32/65 (49%) Frame = -2 Query: 481 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 302 P F NP +DP R+ +++K F + FG G CLG A L++ H+L N Sbjct: 425 PTFFSNPRRFDPTRWL---DKNKDLTHFRNLGFGWGVRQCLGRRIAELEMTLFLIHILEN 481 Query: 301 FEFEL 287 F E+ Sbjct: 482 FRVEI 486
>CP3A5_HUMAN (P20815) Cytochrome P450 3A5 (EC 1.14.14.1) (CYPIIIA5) (P450-PCN3)| (HLp2) Length = 502 Score = 42.0 bits (97), Expect = 0.001 Identities = 23/81 (28%), Positives = 40/81 (49%) Frame = -2 Query: 532 IXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGE 353 I KG V + P + P+ + P+RF+ +++D + + Y FG G C+G Sbjct: 388 IPKGSMVVIPTYALHHDPKYWTEPEEFRPERFS--KKKDSI-DPYIYTPFGTGPRNCIGM 444 Query: 352 PFAYLQIKAIWTHLLRNFEFE 290 FA + +K +L+NF F+ Sbjct: 445 RFALMNMKLALIRVLQNFSFK 465
>CP4AC_RAT (P24464) Cytochrome P450 4A12 (EC 1.14.14.1) (CYPIVA12) (CYPIVA8)| (P450-KP1) (P450-PP1) Length = 508 Score = 42.0 bits (97), Expect = 0.001 Identities = 24/77 (31%), Positives = 37/77 (48%) Frame = -2 Query: 526 KGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPF 347 KG V S + P ++ NP+ +DP RFA + + S++ F GG C+G+ F Sbjct: 405 KGITVMLSFYGLHHNPTVWPNPEVFDPYRFAP----ESSRHSHSFLPFSGGARNCIGKQF 460 Query: 346 AYLQIKAIWTHLLRNFE 296 A ++K L FE Sbjct: 461 AMNELKVAVALTLLRFE 477
>C4AE1_DROME (O46054) Cytochrome P450 4ae1 (EC 1.14.-.-) (CYPIVAE1)| Length = 496 Score = 42.0 bits (97), Expect = 0.001 Identities = 20/60 (33%), Positives = 34/60 (56%) Frame = -2 Query: 475 IFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFE 296 IF +P + P+R EE +SYI F G C+G+ FA L++K + T ++R+++ Sbjct: 408 IFTDPLVFQPERHLG--EEAPRLSPYSYIPFSAGPRNCIGQKFALLEMKTMVTKVIRHYQ 465
>C356_FUNHE (Q8AXY5) Cytochrome P450 3A56 (EC 1.14.14.1) (CYPIIIA56)| Length = 496 Score = 42.0 bits (97), Expect = 0.001 Identities = 19/68 (27%), Positives = 37/68 (54%) Frame = -2 Query: 490 NRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHL 311 +R P I+ P+++ P+RF+ +++ + Y+ FG G C+G FA + IK + Sbjct: 401 HRDPEIWPEPEAFKPERFSKKNKDN--IDPYIYMPFGSGPRNCIGMRFALVLIKLAVVEI 458 Query: 310 LRNFEFEL 287 L+ + F + Sbjct: 459 LQQYSFSV 466
>C330_FUNHE (Q9PVE8) Cytochrome P450 3A30 (EC 1.14.14.1) (CYPIIIA30)| Length = 496 Score = 42.0 bits (97), Expect = 0.001 Identities = 19/68 (27%), Positives = 37/68 (54%) Frame = -2 Query: 490 NRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHL 311 +R P I+ P+++ P+RF+ +++ + Y+ FG G C+G FA + IK + Sbjct: 401 HRDPEIWPEPEAFKPERFSKKNKDN--IDPYIYMPFGSGPRNCIGMRFALVLIKLAVVEI 458 Query: 310 LRNFEFEL 287 L+ + F + Sbjct: 459 LQQYSFSV 466
>CP17A_SHEEP (Q29497) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 509 Score = 42.0 bits (97), Expect = 0.001 Identities = 22/85 (25%), Positives = 39/85 (45%) Frame = -2 Query: 541 EFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGC 362 + I KG V + + ++ PD + P+RF ++ + SY+ FG G C Sbjct: 383 DLTIDKGTDVVVNLWALHHNEKEWQQPDLFMPERFLDPTGTQLISPSLSYLPFGAGPRSC 442 Query: 361 LGEPFAYLQIKAIWTHLLRNFEFEL 287 +GE A ++ + LL+ F E+ Sbjct: 443 VGEMLARQELFLFMSRLLQRFNLEI 467
>CP17A_PIG (P19100) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 509 Score = 42.0 bits (97), Expect = 0.001 Identities = 24/85 (28%), Positives = 38/85 (44%) Frame = -2 Query: 541 EFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGC 362 EF I K V + + + PD + P+RF ++ + SY+ FG G C Sbjct: 383 EFTIDKDTDVVVNLWALHHNEKEWHRPDLFMPERFLDPTGTQLISPSLSYLPFGAGPRSC 442 Query: 361 LGEPFAYLQIKAIWTHLLRNFEFEL 287 +GE A ++ LL+ F+ EL Sbjct: 443 VGEMLARQELFLFTAGLLQRFDLEL 467
>CP17A_CAPHI (Q9N0U7) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 509 Score = 42.0 bits (97), Expect = 0.001 Identities = 22/85 (25%), Positives = 39/85 (45%) Frame = -2 Query: 541 EFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGC 362 + I KG V + + ++ PD + P+RF ++ + SY+ FG G C Sbjct: 383 DLTIDKGTDVVVNLWALHHNEKEWQQPDLFMPERFLDPTGTQLISPSLSYLPFGAGPRSC 442 Query: 361 LGEPFAYLQIKAIWTHLLRNFEFEL 287 +GE A ++ + LL+ F E+ Sbjct: 443 VGEMLARQELFLFMSRLLQRFNLEI 467
>T10H_TAXCU (Q9AXM6) Taxane 10-beta-hydroxylase (EC 1.14.13.76)| (5-alpha-taxadienol-10-beta-hydroxylase) (Cytochrome P450 725A1) Length = 497 Score = 42.0 bits (97), Expect = 0.001 Identities = 23/80 (28%), Positives = 37/80 (46%) Frame = -2 Query: 538 FDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCL 359 + I KG V S + F P+ + P RF +E + ++Y+ FGGG C Sbjct: 388 YTIPKGWRVLCSPYTTHLREEYFPEPEEFRPSRF---EDEGRHVTPYTYVPFGGGLRTCP 444 Query: 358 GEPFAYLQIKAIWTHLLRNF 299 G F+ ++I H ++NF Sbjct: 445 GWEFSKIEILLFVHHFVKNF 464
>CP1A1_LIZSA (Q9W683) Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1)| Length = 521 Score = 41.6 bits (96), Expect = 0.002 Identities = 24/68 (35%), Positives = 36/68 (52%), Gaps = 2/68 (2%) Frame = -2 Query: 490 NRLPHIFKNPDSYDPDRF--AAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWT 317 N P ++K P S++PDRF A G E +KV G + FG G+ C+GE A ++ Sbjct: 420 NHDPELWKEPSSFNPDRFLSADGTEVNKVDGE-KVMIFGMGKRRCIGEVIARNEVYLFLA 478 Query: 316 HLLRNFEF 293 L++ F Sbjct: 479 ILIQKLHF 486
>CP1A1_LIMLI (O42430) Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1)| Length = 521 Score = 41.6 bits (96), Expect = 0.002 Identities = 23/68 (33%), Positives = 38/68 (55%), Gaps = 2/68 (2%) Frame = -2 Query: 490 NRLPHIFKNPDSYDPDRF--AAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWT 317 N P ++K+P S++PDRF A G E +K+ G ++FG G+ C+GE A ++ Sbjct: 420 NHDPEMWKDPSSFNPDRFLSADGSEVNKLDGE-KVMAFGMGKRRCIGEVIARNEVYLFLA 478 Query: 316 HLLRNFEF 293 L++ F Sbjct: 479 ILIQKLHF 486
>CP2DA_MOUSE (P24456) Cytochrome P450 2D10 (EC 1.14.14.1) (CYPIID10)| (P450-16-alpha) (P450CB) (Testosterone 16-alpha hydroxylase) Length = 504 Score = 41.6 bits (96), Expect = 0.002 Identities = 27/97 (27%), Positives = 48/97 (49%), Gaps = 2/97 (2%) Frame = -2 Query: 550 EGKEFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGR 371 E ++F I KG + + + + +++ P + P+ F + AF + F GR Sbjct: 386 EVQDFLIPKGSILIPNMSSVLKDETVWEKPLRFHPEHFLDAQGHFVKPEAF--MPFSAGR 443 Query: 370 HGCLGEPFAYLQIKAIWTHLLRNFEFELVS--PFPEN 266 CLGEP A +++ +T LL++F F + + P P N Sbjct: 444 RSCLGEPLARMELFLFFTCLLQHFSFSVPNGQPRPRN 480
>CP2C7_RAT (P05179) Cytochrome P450 2C7 (EC 1.14.14.1) (CYPIIC7) (P450F)| (PTF1) Length = 490 Score = 41.6 bits (96), Expect = 0.002 Identities = 28/90 (31%), Positives = 41/90 (45%), Gaps = 1/90 (1%) Frame = -2 Query: 544 KEFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHG 365 + + I KG V TS F NP+ +DP F K + F + F G+ Sbjct: 377 RNYLIPKGTKVLTSLTSVLHDSKEFPNPEMFDPGHFLDENGNFKKSDYF--LPFSAGKRA 434 Query: 364 CLGEPFAYLQIKAIWTHLLRNFEFE-LVSP 278 C+GE A +Q+ T +L+NF + LV P Sbjct: 435 CVGEGLARMQLFLFLTTILQNFNLKSLVHP 464
>CP2BJ_MOUSE (O55071) Cytochrome P450 2B19 (EC 1.14.14.1) (CYPIIB19)| Length = 492 Score = 41.6 bits (96), Expect = 0.002 Identities = 27/73 (36%), Positives = 38/73 (52%), Gaps = 1/73 (1%) Frame = -2 Query: 481 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 302 P F+ PDS++P+ F K AF + F G+ CLGE A ++ +T +L+N Sbjct: 400 PRYFEQPDSFNPEHFLDANGALKTNEAF--MPFSTGKRICLGEGIARNELFLFFTTILQN 457 Query: 301 FEFELVSPF-PEN 266 F L SP PEN Sbjct: 458 --FSLASPVAPEN 468
>CP17A_ORYLA (P70085) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 517 Score = 41.6 bits (96), Expect = 0.002 Identities = 22/81 (27%), Positives = 38/81 (46%) Frame = -2 Query: 541 EFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGC 362 +F + KG V + + + NPD ++P RF + + SY+ FG G C Sbjct: 392 DFTVRKGTRVVINLWSLHHDEKEWTNPDLFNPGRFLSADGSSLTLPSSSYLPFGAGLRVC 451 Query: 361 LGEPFAYLQIKAIWTHLLRNF 299 LGE A +++ + +L+ F Sbjct: 452 LGEALAKMELFLFLSWILQRF 472
>C83A1_ARATH (P48421) Cytochrome P450 83A1 (EC 1.14.-.-) (CYPLXXXIII)| Length = 502 Score = 41.6 bits (96), Expect = 0.002 Identities = 28/90 (31%), Positives = 43/90 (47%) Frame = -2 Query: 466 NPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL 287 NPD + P+RF +E D + +I FG GR C G ++ + +LL +F F+L Sbjct: 409 NPDEFRPERFLE-KEVDFKGTDYEFIPFGSGRRMCPGMRLGAAMLEVPYANLLLSFNFKL 467 Query: 286 VSPFPENDWNAMVVGIKGEVMVNYKRRKLV 197 + +D N V + G M + KLV Sbjct: 468 PNGMKPDDINMDV--MTGLAMHKSQHLKLV 495
>C82A1_PEA (Q43068) Cytochrome P450 82A1 (EC 1.14.-.-) (CYPLXXXII) (Fragment)| Length = 544 Score = 41.6 bits (96), Expect = 0.002 Identities = 25/92 (27%), Positives = 45/92 (48%), Gaps = 1/92 (1%) Frame = -2 Query: 538 FDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGA-FSYISFGGGRHGC 362 + I KG + + +R P ++ +P + P+RF + ++ V G F + FG GR C Sbjct: 422 YHIKKGTRLMPNLWKIHRDPSVWPDPLEFKPERFLSTHKDVDVRGQNFELLPFGSGRRMC 481 Query: 361 LGEPFAYLQIKAIWTHLLRNFEFELVSPFPEN 266 G + I + L + FE+++P PE+ Sbjct: 482 AGMSLGLHMVHYILANFLHS--FEILNPSPES 511
>C71A8_MENPI (Q42716) Cytochrome P450 71A8 (EC 1.14.-.-)| Length = 502 Score = 41.6 bits (96), Expect = 0.002 Identities = 24/84 (28%), Positives = 39/84 (46%) Frame = -2 Query: 538 FDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCL 359 +D+ G V + R P + P+ + P+RF + K F I FG GR GC Sbjct: 390 YDVPVGTMVMINAWAIGRDPTSWDEPEKFRPERFLNSSVDFKGLD-FELIPFGAGRRGCP 448 Query: 358 GEPFAYLQIKAIWTHLLRNFEFEL 287 G F ++ +L++ F++EL Sbjct: 449 GTTFPMATLEFTLANLMQKFDWEL 472
>C11B1_BOVIN (P15150) Cytochrome P450 11B1, mitochondrial precursor (EC| 1.14.15.4) (CYPXIB1) (P450C11) (Steroid 11-beta-hydroxylase) Length = 503 Score = 41.6 bits (96), Expect = 0.002 Identities = 24/85 (28%), Positives = 39/85 (45%) Frame = -2 Query: 544 KEFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHG 365 + + I G V R P +F P+SY P R+ + F +++FG G Sbjct: 393 QNYHIPAGTLVKVLLYSLGRNPAVFARPESYHPQRWL---DRQGSGSRFPHLAFGFGVRQ 449 Query: 364 CLGEPFAYLQIKAIWTHLLRNFEFE 290 CLG A +++ + H+L+NF E Sbjct: 450 CLGRRVAEVEMLLLLHHVLKNFLVE 474
>C5B3_AMYOR (Q8RN04) Cytochrome P450 165B3 (EC 1.14.-.-) (Vancomycin| biosynthesis protein oxyB) Length = 398 Score = 41.2 bits (95), Expect = 0.002 Identities = 27/79 (34%), Positives = 38/79 (48%) Frame = -2 Query: 535 DIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLG 356 +I KG V S ANR P + + D DR RE +++FG G H CLG Sbjct: 301 EIKKGDSVICSLPAANRDPAL-----APDVDRLDVTREP------IPHVAFGHGVHHCLG 349 Query: 355 EPFAYLQIKAIWTHLLRNF 299 A L+++ ++T L R F Sbjct: 350 AALARLELRTVFTELWRRF 368
>F3PH_ARATH (Q9SD85) Flavonoid 3'-monooxygenase (EC 1.14.13.21) (Flavonoid| 3'-hydroxylase) (AtF3'H) (Cytochrome P450 75B1) (TRANSPARENT TESTA 7 protein) Length = 513 Score = 41.2 bits (95), Expect = 0.002 Identities = 26/87 (29%), Positives = 41/87 (47%), Gaps = 3/87 (3%) Frame = -2 Query: 538 FDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKV---AGAFSYISFGGGRH 368 + I KG + T+ R P + +P ++ P+RF G E+ V F I FG GR Sbjct: 384 YHIPKGSTLLTNIWAIARDPDQWSDPLAFKPERFLPGGEKSGVDVKGSDFELIPFGAGRR 443 Query: 367 GCLGEPFAYLQIKAIWTHLLRNFEFEL 287 C G I+ + L++ F++EL Sbjct: 444 ICAGLSLGLRTIQFLTATLVQGFDWEL 470
>CP3AV_MESAU (O70537) Cytochrome P450 3A31 (EC 1.14.14.1) (CYPIIIA31) (P450| SH3A-1) Length = 501 Score = 41.2 bits (95), Expect = 0.002 Identities = 21/81 (25%), Positives = 38/81 (46%) Frame = -2 Query: 532 IXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGE 353 + KG V + P + P+ + P+RF+ +E + ++ FG G C+G Sbjct: 386 VPKGSIVMVPVFALHYDPQYWPEPEKFRPERFS--KENKGSIDPYIFLPFGNGPRNCIGM 443 Query: 352 PFAYLQIKAIWTHLLRNFEFE 290 FA + +K T +L+NF + Sbjct: 444 RFALMNMKLALTKVLQNFSLQ 464
>CP2D1_RAT (P10633) Cytochrome P450 2D1 (EC 1.14.14.1) (CYPIID1) (P450-DB1)| (P450-CMF1A) (P450-UT-7) (Debrisoquine 4-hydroxylase) Length = 504 Score = 41.2 bits (95), Expect = 0.002 Identities = 24/88 (27%), Positives = 43/88 (48%) Frame = -2 Query: 550 EGKEFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGR 371 E ++F I KG + + + + +++ P + P+ F + AF + F GR Sbjct: 386 EVQDFVIPKGTTLIINLSSVLKDETVWEKPHRFHPEHFLDAQGNFVKHEAF--MPFSAGR 443 Query: 370 HGCLGEPFAYLQIKAIWTHLLRNFEFEL 287 CLGEP A +++ +T LL+ F F + Sbjct: 444 RACLGEPLARMELFLFFTCLLQRFSFSV 471
>CP237_MOUSE (P56654) Cytochrome P450 2C37 (EC 1.14.14.1) (CYPIIC37)| Length = 490 Score = 41.2 bits (95), Expect = 0.002 Identities = 27/102 (26%), Positives = 48/102 (47%) Frame = -2 Query: 544 KEFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHG 365 + + I KG V TS + F NP+ +DP F G + K + F + F G+ Sbjct: 377 RNYFIPKGTTVITSLSSVLHDSTEFPNPEVFDPGHFLDGNGKFKKSDYF--MPFSTGKRI 434 Query: 364 CLGEPFAYLQIKAIWTHLLRNFEFELVSPFPENDWNAMVVGI 239 C GE A +++ T +L++F + + + D M++G+ Sbjct: 435 CAGEGLARMELFLFLTSILQSFNLKPLVHPKDIDVTPMLIGL 476
>ERG5_YEAST (P54781) Cytochrome P450 61 (EC 1.14.14.-) (C-22 sterol desaturase)| Length = 538 Score = 41.2 bits (95), Expect = 0.002 Identities = 22/93 (23%), Positives = 46/93 (49%), Gaps = 1/93 (1%) Frame = -2 Query: 481 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 302 P +++NPD + P+R+ G + + +++ FG G H CLG+ + + A+ Sbjct: 439 PEVYENPDEFIPERWVEGSKASEAKK--NWLVFGCGPHVCLGQTYVMITFAALLGKFALY 496 Query: 301 FEF-ELVSPFPENDWNAMVVGIKGEVMVNYKRR 206 +F V+P E + K ++++ +K+R Sbjct: 497 TDFHHTVTPLSEKIKVFATIFPKDDLLLTFKKR 529
>CP134_DROME (Q9VG40) Probable cytochrome P450 313a4 (EC 1.14.-.-)| (CYPCCCXIIIA4) Length = 478 Score = 41.2 bits (95), Expect = 0.002 Identities = 25/87 (28%), Positives = 42/87 (48%), Gaps = 1/87 (1%) Frame = -2 Query: 532 IXKGHXVATSXAFANRLPHIF-KNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLG 356 + KG +A +R I+ + ++++PD F +DK ++YI F G C+G Sbjct: 369 VPKGVQIAIDIYHMHRSKKIWGPDAETFNPDHFLPHNIQDK--HPYAYIPFTKGIRNCIG 426 Query: 355 EPFAYLQIKAIWTHLLRNFEFELVSPF 275 +A + K LLRN+ F+ PF Sbjct: 427 WRYALISAKVTLAKLLRNYRFKTSFPF 453
>C28D1_DROME (Q9VMT5) Probable cytochrome P450 28d1 (EC 1.14.-.-) (CYPXXVIIID1)| Length = 502 Score = 41.2 bits (95), Expect = 0.002 Identities = 33/126 (26%), Positives = 55/126 (43%), Gaps = 7/126 (5%) Frame = -2 Query: 562 VXTREGKEFDIXKGHXVATSXAFANRLPHIFKNPDSYDPDRFA---AGREEDKVAGAFSY 392 + + G + G V + P ++ P S+ P+RF G ++ + G F Sbjct: 379 LTNKNGVSVKLRPGDVVIIPVNALHHDPQYYEEPQSFKPERFLNINGGAKKYRDQGLF-- 436 Query: 391 ISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFP----ENDWNAMVVGIKGEVM 224 FG G C G F+ QIKA ++RNF+ + V+P E D + +KG V Sbjct: 437 FGFGDGPRICPGMRFSLTQIKAALVEIVRNFDIK-VNPKTRKDNEIDDTYFMPALKGGVW 495 Query: 223 VNYKRR 206 +++ R Sbjct: 496 LDFVER 501
>CP1A1_PLEPL (Q92100) Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1)| Length = 521 Score = 41.2 bits (95), Expect = 0.002 Identities = 22/68 (32%), Positives = 38/68 (55%), Gaps = 2/68 (2%) Frame = -2 Query: 490 NRLPHIFKNPDSYDPDRF--AAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWT 317 N P ++K+P S++PDRF A G E +K+ G ++FG G+ C+GE A ++ Sbjct: 420 NHDPELWKDPSSFNPDRFLSADGSEVNKLDGE-KVMAFGMGKRRCIGEVIARNEVYLFLA 478 Query: 316 HLLRNFEF 293 +++ F Sbjct: 479 IIIQKLHF 486
>CP1A1_PLAFE (Q9YH64) Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1)| Length = 521 Score = 41.2 bits (95), Expect = 0.002 Identities = 22/68 (32%), Positives = 38/68 (55%), Gaps = 2/68 (2%) Frame = -2 Query: 490 NRLPHIFKNPDSYDPDRF--AAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWT 317 N P ++K+P S++PDRF A G E +K+ G ++FG G+ C+GE A ++ Sbjct: 420 NHDPELWKDPSSFNPDRFLSADGSEVNKLDGE-KVMAFGMGKRRCIGEVIARNEVYLFLA 478 Query: 316 HLLRNFEF 293 +++ F Sbjct: 479 IIIQKLHF 486
>CP1A1_LIZAU (O42231) Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1)| Length = 521 Score = 41.2 bits (95), Expect = 0.002 Identities = 24/68 (35%), Positives = 36/68 (52%), Gaps = 2/68 (2%) Frame = -2 Query: 490 NRLPHIFKNPDSYDPDRF--AAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWT 317 N P ++K P S++PDRF A G E +KV G + FG G+ C+GE A ++ Sbjct: 420 NHDPELWKEPSSFNPDRFLSADGTEVNKVDGE-KVMVFGLGKRRCIGEVIARNEVYMFLA 478 Query: 316 HLLRNFEF 293 L++ F Sbjct: 479 ILIQKLHF 486
>CP1A1_CHACA (Q92039) Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1)| Length = 521 Score = 41.2 bits (95), Expect = 0.002 Identities = 27/81 (33%), Positives = 43/81 (53%), Gaps = 7/81 (8%) Frame = -2 Query: 490 NRLPHIFKNPDSYDPDRFAA--GREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWT 317 NR P ++K+P S++PDRF + G E +K G + FG G+ C+GE A ++ Sbjct: 420 NRDPELWKDPSSFNPDRFLSCNGTEVNKQEGE-KVMVFGMGKRRCIGEVIARNEVYRGLA 478 Query: 316 HLLRNFEF-----ELVSPFPE 269 L++ +F EL+ PE Sbjct: 479 ILIQRLQFHEMPGELLDMTPE 499
>CP1A3_ONCMY (Q92109) Cytochrome P450 1A3 (EC 1.14.14.1) (CYP1A3) (CYP1A1)| Length = 522 Score = 41.2 bits (95), Expect = 0.002 Identities = 23/69 (33%), Positives = 36/69 (52%), Gaps = 2/69 (2%) Frame = -2 Query: 490 NRLPHIFKNPDSYDPDRF--AAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWT 317 N P ++K P S++PDRF A G E +K+ G + FG G+ C+GE ++ Sbjct: 420 NHDPELWKEPSSFNPDRFLSADGTELNKLEGE-KVLVFGMGKRRCIGEAIGRNEVYLFLA 478 Query: 316 HLLRNFEFE 290 LL+ F+ Sbjct: 479 ILLQRLRFQ 487 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 74,376,576 Number of Sequences: 219361 Number of extensions: 1443014 Number of successful extensions: 4730 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 4434 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4510 length of database: 80,573,946 effective HSP length: 106 effective length of database: 57,321,680 effective search space used: 4815021120 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
