ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | rbaal2c04 |
|---|---|
| Clone Library Name | barley_pub |
>RPK1_IPONI (P93194) Receptor-like protein kinase precursor (EC 2.7.11.1)| Length = 1109 Score = 87.8 bits (216), Expect = 3e-17 Identities = 57/168 (33%), Positives = 83/168 (49%), Gaps = 2/168 (1%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 I+H D+KP NILLD D+ H+ DFGIA++ S A+S S V+ Sbjct: 938 IVHRDIKPMNILLDSDLEPHISDFGIAKLLDQS----ATSIPSNTVQGTIGYMAPENAFT 993 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRPTDPMFTDGLDIVNFVGSEFPH--QIHEVIDIYLKG 423 S DVYS+G+VLLE++T K+ DP F DIV +V S + +I +++D L Sbjct: 994 TVKSRESDVYSYGVVLLELITRKKALDPSFNGETDIVGWVRSVWTQTGEIQKIVDPSLLD 1053 Query: 422 ECEDSAEARSVSEGSVHQCLVSLLQVAVSCTHSIPSERANMRDAASKI 279 E DS+ V+E L +A+ C +R MRD ++ Sbjct: 1054 ELIDSSVMEQVTEA---------LSLALRCAEKEVDKRPTMRDVVKQL 1092
>BRL2_ARATH (Q9ZPS9) Serine/threonine-protein kinase BRI1-like 2 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 2) (Protein VASCULAR HIGHWAY 1) Length = 1143 Score = 85.5 bits (210), Expect = 2e-16 Identities = 56/175 (32%), Positives = 87/175 (49%), Gaps = 3/175 (1%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 IIH D+K SN+LLD DM A + DFG+AR+ + ST + Sbjct: 962 IIHRDMKSSNVLLDQDMEARVSDFGMARLISALDTHLSVST----LAGTPGYVPPEYYQS 1017 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRPTDPMFTDGLDIVNFVGSEFPHQIH-EVI--DIYLK 426 R + GDVYS G+V+LE+L+GKRPTD ++V + + H EVI D+ + Sbjct: 1018 FRCTAKGDVYSIGVVMLEILSGKRPTDKEEFGDTNLVGWSKMKAREGKHMEVIDEDLLKE 1077 Query: 425 GECEDSAEARSVSEGSVHQCLVSLLQVAVSCTHSIPSERANMRDAASKIQAIQAS 261 G E E G + + ++ L++A+ C PS+R NM + ++ ++ S Sbjct: 1078 GSSESLNEKEGFEGGVIVKEMLRYLEIALRCVDDFPSKRPNMLQVVASLRELRGS 1132
>EXS_ARATH (Q9LYN8) Leucine-rich repeat receptor protein kinase EXS precursor| (EC 2.7.11.1) (Extra sporogenous cells protein) (EXCESS MICROSPOROCYTES1 protein) Length = 1192 Score = 80.9 bits (198), Expect = 4e-15 Identities = 56/169 (33%), Positives = 81/169 (47%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 IIH D+K SNILLD D + DFG+AR+ S S + Sbjct: 1039 IIHRDIKASNILLDGDFEPKVADFGLARLI-----SACESHVSTVIAGTFGYIPPEYGQS 1093 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRPTDPMFTDGLDIVNFVGSEFPHQIHEVIDIYLKGEC 417 R +T GDVYSFG++LLE++TGK PT P F + SE + + I +G+ Sbjct: 1094 ARATTKGDVYSFGVILLELVTGKEPTGPDFKE---------SEGGNLVGWAIQKINQGKA 1144 Query: 416 EDSAEARSVSEGSVHQCLVSLLQVAVSCTHSIPSERANMRDAASKIQAI 270 D + VS ++ + LLQ+A+ C P++R NM D ++ I Sbjct: 1145 VDVIDPLLVSV-ALKNSQLRLLQIAMLCLAETPAKRPNMLDVLKALKEI 1192
>BRI1_ARATH (O22476) BRASSINOSTEROID INSENSITIVE 1 precursor (EC 2.7.11.1)| (AtBRI1) (Brassinosteroid LRR receptor kinase) Length = 1196 Score = 79.3 bits (194), Expect = 1e-14 Identities = 60/172 (34%), Positives = 86/172 (50%), Gaps = 1/172 (0%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 IIH D+K SN+LLD+++ A + DFG+AR+ + ST + Sbjct: 1005 IIHRDMKSSNVLLDENLEARVSDFGMARLMSAMDTHLSVST----LAGTPGYVPPEYYQS 1060 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRPTD-PMFTDGLDIVNFVGSEFPHQIHEVIDIYLKGE 420 R ST GDVYS+G+VLLE+LTGKRPTD P F D ++V +V +I +V D L E Sbjct: 1061 FRCSTKGDVYSYGVVLLELLTGKRPTDSPDFGDN-NLVGWVKQHAKLRISDVFDPELMKE 1119 Query: 419 CEDSAEARSVSEGSVHQCLVSLLQVAVSCTHSIPSERANMRDAASKIQAIQA 264 + ++ L+ L+VAV+C R M + + IQA Sbjct: 1120 -----------DPALEIELLQHLKVAVACLDDRAWRRPTMVQVMAMFKEIQA 1160
>BRI1_LYCPE (Q8L899) Systemin receptor SR160 precursor (EC 2.7.11.1)| (Brassinosteroid LRR receptor kinase) Length = 1207 Score = 76.6 bits (187), Expect = 8e-14 Identities = 56/171 (32%), Positives = 83/171 (48%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 IIH D+K SN+LLD+++ A + DFG+AR+ + ST + Sbjct: 1010 IIHRDMKSSNVLLDENLEARVSDFGMARLMSAMDTHLSVST----LAGTPGYVPPEYYQS 1065 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRPTDPMFTDGLDIVNFVGSEFPHQIHEVIDIYLKGEC 417 R ST GDVYS+G+VLLE+LTGK+PTD ++V +V +I +V D L E Sbjct: 1066 FRCSTKGDVYSYGVVLLELLTGKQPTDSADFGDNNLVGWVKLHAKGKITDVFDRELLKE- 1124 Query: 416 EDSAEARSVSEGSVHQCLVSLLQVAVSCTHSIPSERANMRDAASKIQAIQA 264 + S+ L+ L+VA +C +R M + + IQA Sbjct: 1125 ----------DASIEIELLQHLKVACACLDDRHWKRPTMIQVMAMFKEIQA 1165
>BRI1_LYCES (Q8GUQ5) Brassinosteroid LRR receptor kinase precursor (EC 2.7.11.1)| (tBRI1) (Altered brassinolide sensitivity 1) (Systemin receptor SR160) Length = 1207 Score = 76.6 bits (187), Expect = 8e-14 Identities = 56/171 (32%), Positives = 83/171 (48%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 IIH D+K SN+LLD+++ A + DFG+AR+ + ST + Sbjct: 1010 IIHRDMKSSNVLLDENLEARVSDFGMARLMSAMDTHLSVST----LAGTPGYVPPEYYQS 1065 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRPTDPMFTDGLDIVNFVGSEFPHQIHEVIDIYLKGEC 417 R ST GDVYS+G+VLLE+LTGK+PTD ++V +V +I +V D L E Sbjct: 1066 FRCSTKGDVYSYGVVLLELLTGKQPTDSADFGDNNLVGWVKLHAKGKITDVFDRELLKE- 1124 Query: 416 EDSAEARSVSEGSVHQCLVSLLQVAVSCTHSIPSERANMRDAASKIQAIQA 264 + S+ L+ L+VA +C +R M + + IQA Sbjct: 1125 ----------DASIEIELLQHLKVACACLDDRHWKRPTMIQVMAMFKEIQA 1165
>RLK5_ARATH (P47735) Receptor-like protein kinase 5 precursor (EC 2.7.11.1)| Length = 999 Score = 75.5 bits (184), Expect = 2e-13 Identities = 51/173 (29%), Positives = 83/173 (47%), Gaps = 1/173 (0%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 I+H D+K SNILLD D A + DFGIA++ SG + + S G+ Sbjct: 815 IVHRDVKSSNILLDSDYGAKVADFGIAKVGQMSGSKTPEAMS--GIAGSCGYIAPEYVYT 872 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRPTDPMFTDGLDIVNFVGSEFPH-QIHEVIDIYLKGE 420 R++ D+YSFG+VLLE++TGK+PTD D D+ +V + + VID L + Sbjct: 873 LRVNEKSDIYSFGVVLLELVTGKQPTDSELGD-KDMAKWVCTALDKCGLEPVIDPKLDLK 931 Query: 419 CEDSAEARSVSEGSVHQCLVSLLQVAVSCTHSIPSERANMRDAASKIQAIQAS 261 ++ + ++ + + CT +P R +MR +Q + + Sbjct: 932 FKEE--------------ISKVIHIGLLCTSPLPLNRPSMRKVVIMLQEVSGA 970
>CLV1_ARATH (Q9SYQ8) Receptor protein kinase CLAVATA1 precursor (EC 2.7.11.1)| Length = 980 Score = 72.4 bits (176), Expect = 1e-12 Identities = 38/100 (38%), Positives = 56/100 (56%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 I+H D+K +NILLD D AH+ DFG+A+ +D A+S + Sbjct: 813 ILHRDVKSNNILLDSDFEAHVADFGLAKFLVDG----AASECMSSIAGSYGYIAPEYAYT 868 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRPTDPMFTDGLDIVNFV 477 ++ DVYSFG+VLLE++ GK+P F +G+DIV +V Sbjct: 869 LKVDEKSDVYSFGVVLLELIAGKKPVGE-FGEGVDIVRWV 907
>PSKR_DAUCA (Q8LPB4) Phytosulfokine receptor precursor (EC 2.7.11.1)| (Phytosulfokine LRR receptor kinase) Length = 1021 Score = 71.2 bits (173), Expect = 3e-12 Identities = 55/176 (31%), Positives = 82/176 (46%), Gaps = 4/176 (2%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 I+H D+K SNILL D VAHL DFG+AR+ L P + + + Sbjct: 865 ILHRDIKSSNILLSDTFVAHLADFGLARLIL-----PYDTHVTTDLVGTLGYIPPEYGQA 919 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRPTDPMFTDG-LDIVNFV-GSEFPHQIHEVID--IYL 429 + GDVYSFG+VLLE+LTG+RP D G D++++V + + E+ D IY Sbjct: 920 SVATYKGDVYSFGVVLLELLTGRRPMDVCKPRGSRDLISWVLQMKTEKRESEIFDPFIYD 979 Query: 428 KGECEDSAEARSVSEGSVHQCLVSLLQVAVSCTHSIPSERANMRDAASKIQAIQAS 261 K E+ ++ +L++A C P R + S ++ I S Sbjct: 980 KDHAEE---------------MLLVLEIACRCLGENPKTRPTTQQLVSWLENIDVS 1020
>BRL1_ARATH (Q9ZWC8) Serine/threonine-protein kinase BRI1-like 1 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 1) Length = 1166 Score = 68.2 bits (165), Expect = 3e-11 Identities = 54/199 (27%), Positives = 91/199 (45%), Gaps = 1/199 (0%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 IIH D+K SN+LLD+D A + DFG+AR+ + ST + Sbjct: 983 IIHRDMKSSNVLLDEDFEARVSDFGMARLVSALDTHLSVST----LAGTPGYVPPEYYQS 1038 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRPTDP-MFTDGLDIVNFVGSEFPHQIHEVIDIYLKGE 420 R + GDVYS+G++LLE+L+GK+P DP F + ++V + +Y + Sbjct: 1039 FRCTAKGDVYSYGVILLELLSGKKPIDPGEFGEDNNLVGWAK-----------QLYREKR 1087 Query: 419 CEDSAEARSVSEGSVHQCLVSLLQVAVSCTHSIPSERANMRDAASKIQAIQASYLGRQT* 240 + + V++ S L L++A C P +R M + + ++A ++ Sbjct: 1088 GAEILDPELVTDKSGDVELFHYLKIASQCLDDRPFKRPTMIQLMAMFKEMKADTEEDES- 1146 Query: 239 ILQFNYVHTTTTYTSRQKE 183 + +F+ T SR KE Sbjct: 1147 LDEFSLKETPLVEESRDKE 1165
>BRL3_ARATH (Q9LJF3) Serine/threonine-protein kinase BRI1-like 3 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 3) Length = 1164 Score = 68.2 bits (165), Expect = 3e-11 Identities = 48/160 (30%), Positives = 76/160 (47%), Gaps = 1/160 (0%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 IIH D+K SN+LLD D VA + DFG+AR+ + ST + Sbjct: 981 IIHRDMKSSNVLLDQDFVARVSDFGMARLVSALDTHLSVST----LAGTPGYVPPEYYQS 1036 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRPTDP-MFTDGLDIVNFVGSEFPHQIHEVIDIYLKGE 420 R + GDVYS+G++LLE+L+GK+P DP F + ++V + +Y + Sbjct: 1037 FRCTAKGDVYSYGVILLELLSGKKPIDPEEFGEDNNLVGWAK-----------QLYREKR 1085 Query: 419 CEDSAEARSVSEGSVHQCLVSLLQVAVSCTHSIPSERANM 300 + + V++ S L+ L++A C P +R M Sbjct: 1086 GAEILDPELVTDKSGDVELLHYLKIASQCLDDRPFKRPTM 1125
>PSKR_ARATH (Q9ZVR7) Putative phytosulfokine receptor precursor (EC 2.7.11.1)| (Phytosulfokine LRR receptor kinase) Length = 1008 Score = 66.2 bits (160), Expect = 1e-10 Identities = 52/166 (31%), Positives = 76/166 (45%), Gaps = 2/166 (1%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 I+H D+K SNILLD++ +HL DFG+AR+ S ST +G Sbjct: 856 ILHRDIKSSNILLDENFNSHLADFGLARLM--SPYETHVSTDLVGTLGYIPPEYGQASVA 913 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRPTDPMFTDGL-DIVNF-VGSEFPHQIHEVIDIYLKG 423 + GDVYSFG+VLLE+LT KRP D G D++++ V + + EV D + Sbjct: 914 ---TYKGDVYSFGVVLLELLTDKRPVDMCKPKGCRDLISWVVKMKHESRASEVFDPLIYS 970 Query: 422 ECEDSAEARSVSEGSVHQCLVSLLQVAVSCTHSIPSERANMRDAAS 285 + D R +L++A C P +R + S Sbjct: 971 KENDKEMFR-------------VLEIACLCLSENPKQRPTTQQLVS 1003
>KPRO_MAIZE (P17801) Putative receptor protein kinase ZmPK1 precursor (EC| 2.7.11.1) Length = 817 Score = 65.9 bits (159), Expect = 1e-10 Identities = 53/173 (30%), Positives = 79/173 (45%), Gaps = 7/173 (4%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIG-VRXXXXXXXXXXXX 600 +IHCD+KP NILLD + DFG+ ++ G ST ++ VR Sbjct: 654 VIHCDVKPENILLDQAFEPKITDFGLVKLLNRGG-----STQNVSHVRGTLGYIAPEWVS 708 Query: 599 XGRISTSGDVYSFGIVLLEMLTGKR------PTDPMFTDGLDIVNFVGSEFPHQIHEVID 438 I+ DVYS+G+VLLE+LTG R TD + + +V + ++ + ID Sbjct: 709 SLPITAKVDVYSYGVVLLELLTGTRVSELVGGTDEVHSMLRKLVRMLSAKLEGEEQSWID 768 Query: 437 IYLKGECEDSAEARSVSEGSVHQCLVSLLQVAVSCTHSIPSERANMRDAASKI 279 YL DS R V+ +L+++AVSC S+R M A + Sbjct: 769 GYL-----DSKLNRPVNYVQAR----TLIKLAVSCLEEDRSKRPTMEHAVQTL 812
>BAK1_ARATH (Q94F62) BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1| precursor (EC 2.7.11.1) (BRI1-associated receptor kinase 1) (Somatic embryogenesis receptor-like kinase 3) Length = 615 Score = 65.1 bits (157), Expect = 2e-10 Identities = 48/171 (28%), Positives = 84/171 (49%), Gaps = 4/171 (2%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 IIH D+K +NILLD++ A +GDFG+A++ + + VR Sbjct: 412 IIHRDVKAANILLDEEFEAVVGDFGLAKLM-----DYKDTHVTTAVRGTIGHIAPEYLST 466 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRPTD---PMFTDGLDIVNFV-GSEFPHQIHEVIDIYL 429 G+ S DV+ +G++LLE++TG+R D D + ++++V G ++ ++D+ L Sbjct: 467 GKSSEKTDVFGYGVMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKLEALVDVDL 526 Query: 428 KGECEDSAEARSVSEGSVHQCLVSLLQVAVSCTHSIPSERANMRDAASKIQ 276 +G +D + L+QVA+ CT S P ER M + ++ Sbjct: 527 QGNYKDEE-------------VEQLIQVALLCTQSSPMERPKMSEVVRMLE 564
>NORK_MEDTR (Q8L4H4) Nodulation receptor kinase precursor (EC 2.7.11.1) (Does not| make infections protein 2) (Symbiosis receptor-like kinase) (MtSYMRK) Length = 925 Score = 63.9 bits (154), Expect = 5e-10 Identities = 44/167 (26%), Positives = 73/167 (43%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 +IH D+K SNILLD M A + DFG ++ P+ S S+ VR Sbjct: 718 VIHRDVKSSNILLDQSMCAKVADFGFSKY----APQEGDSYVSLEVRGTAGYLDPEYYKT 773 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRPTDPMFTDGLDIVNFVGSEFPHQIHEVIDIYLKGEC 417 ++S DV+SFG+VLLE+++G+ P +N + E Y++ Sbjct: 774 QQLSEKSDVFSFGVVLLEIVSGREP-----------LNIKRPRIEWSLVEWAKPYIRASK 822 Query: 416 EDSAEARSVSEGSVHQCLVSLLQVAVSCTHSIPSERANMRDAASKIQ 276 D + G + L +++VA+ C + R M D +++ Sbjct: 823 VDEIVDPGIKGGYHAEALWRVVEVALQCLEPYSTYRPCMVDIVRELE 869
>TMK1_ARATH (P43298) Putative receptor protein kinase TMK1 precursor (EC| 2.7.11.1) Length = 942 Score = 63.5 bits (153), Expect = 7e-10 Identities = 44/140 (31%), Positives = 72/140 (51%), Gaps = 4/140 (2%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 IH DLKPSNILL DDM A + DFG+ R+ P S + + G Sbjct: 714 IHRDLKPSNILLGDDMRAKVADFGLVRL----APEGKGSIET-RIAGTFGYLAPEYAVTG 768 Query: 593 RISTSGDVYSFGIVLLEMLTGKRPTD-PMFTDGLDIVNFVGSEFPHQ---IHEVIDIYLK 426 R++T DVYSFG++L+E++TG++ D + + +V++ + ++ + ID + Sbjct: 769 RVTTKVDVYSFGVILMELITGRKSLDESQPEESIHLVSWFKRMYINKEASFKKAIDTTID 828 Query: 425 GECEDSAEARSVSEGSVHQC 366 + E A +V+E + H C Sbjct: 829 LDEETLASVHTVAELAGHCC 848
>KPEL_DROME (Q05652) Probable serine/threonine-protein kinase pelle (EC| 2.7.11.1) Length = 501 Score = 63.2 bits (152), Expect = 9e-10 Identities = 45/170 (26%), Positives = 79/170 (46%), Gaps = 3/170 (1%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIG-VRXXXXXXXXXXXX 600 +IH D+KP+NILLD + +GDFG+ R GP+ + + V Sbjct: 342 LIHGDIKPANILLDQCLQPKIGDFGLVR----EGPKSLDAVVEVNKVFGTKIYLPPEFRN 397 Query: 599 XGRISTSGDVYSFGIVLLEMLTGKRPTD--PMFTDGLDIVNFVGSEFPHQIHEVIDIYLK 426 ++ST DVYSFGIVLLE+ TG++ TD P +++++V ++ E+++ +L Sbjct: 398 FRQLSTGVDVYSFGIVLLEVFTGRQVTDRVPENETKKNLLDYVKQQWRQNRMELLEKHL- 456 Query: 425 GECEDSAEARSVSEGSVHQCLVSLLQVAVSCTHSIPSERANMRDAASKIQ 276 + G + ++ + CT P +R +M + + Sbjct: 457 ----------AAPMGKELDMCMCAIEAGLHCTALDPQDRPSMNAVLKRFE 496
>NORK_PEA (Q8LKZ1) Nodulation receptor kinase precursor (EC 2.7.11.1)| Length = 924 Score = 63.2 bits (152), Expect = 9e-10 Identities = 44/167 (26%), Positives = 73/167 (43%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 +IH D+K SNILLD M A + DFG ++ P+ S S+ VR Sbjct: 717 VIHRDVKSSNILLDHSMCAKVADFGFSKY----APQEGDSYVSLEVRGTAGYLDPEYYKT 772 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRPTDPMFTDGLDIVNFVGSEFPHQIHEVIDIYLKGEC 417 ++S DV+SFG+VLLE+++G+ P +N + E Y++ Sbjct: 773 QQLSEKSDVFSFGVVLLEIVSGREP-----------LNIKRPRVEWSLVEWAKPYIRASK 821 Query: 416 EDSAEARSVSEGSVHQCLVSLLQVAVSCTHSIPSERANMRDAASKIQ 276 D + G + L +++VA+ C + R M D +++ Sbjct: 822 VDEIVDPGIKGGYHAEALWRVVEVALQCLEPYSTYRPCMVDIVRELE 868
>SIRK_ARATH (O64483) Senescence-induced receptor-like serine/threonine-protein| kinase precursor (FLG22-induced receptor-like kinase 1) Length = 876 Score = 61.6 bits (148), Expect = 3e-09 Identities = 48/170 (28%), Positives = 80/170 (47%), Gaps = 1/170 (0%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 I+H D+KP+NILL++ + A + DFG++R F G S S V Sbjct: 693 IVHRDVKPTNILLNEKLQAKMADFGLSRSFSVEG----SGQISTVVAGSIGYLDPEYYST 748 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRPTDPMFTDGLDIVNFVGSEFPH-QIHEVIDIYLKGE 420 +++ DVYS G+VLLE++TG+ T+ + I + V S + I ++D L+ E Sbjct: 749 RQMNEKSDVYSLGVVLLEVITGQPAIASSKTEKVHISDHVRSILANGDIRGIVDQRLR-E 807 Query: 419 CEDSAEARSVSEGSVHQCLVSLLQVAVSCTHSIPSERANMRDAASKIQAI 270 D A +SE +A++CT ++R M +++ I Sbjct: 808 RYDVGSAWKMSE------------IALACTEHTSAQRPTMSQVVMELKQI 845
>NAK_ARATH (P43293) Probable serine/threonine-protein kinase NAK (EC 2.7.11.1)| Length = 389 Score = 61.6 bits (148), Expect = 3e-09 Identities = 37/87 (42%), Positives = 47/87 (54%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 +I+ D K SNILLD + A L DFG+AR GP +S S V Sbjct: 199 VIYRDFKASNILLDSNYNAKLSDFGLAR----DGPMGDNSHVSTRVMGTQGYAAPEYLAT 254 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRPTD 516 G +S DVYSFG+VLLE+L+G+R D Sbjct: 255 GHLSVKSDVYSFGVVLLELLSGRRAID 281
>APK1A_ARATH (Q06548) Protein kinase APK1A, chloroplast precursor (EC 2.7.11.1)| Length = 410 Score = 61.6 bits (148), Expect = 3e-09 Identities = 57/176 (32%), Positives = 83/176 (47%), Gaps = 5/176 (2%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 +I+ D K SNILLD + A L DFG+A+ GP S S V Sbjct: 199 VIYRDFKTSNILLDSEYNAKLSDFGLAK----DGPIGDKSHVSTRVMGTHGYAAPEYLAT 254 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRPTDPMFTDGLDIVNFVGSEFPH-----QIHEVIDIY 432 G ++T DVYSFG+VLLE+L+G+R D G N V P+ +I VID Sbjct: 255 GHLTTKSDVYSFGVVLLELLSGRRAVDKNRPSGER--NLVEWAKPYLVNKRKIFRVIDNR 312 Query: 431 LKGECEDSAEARSVSEGSVHQCLVSLLQVAVSCTHSIPSERANMRDAASKIQAIQA 264 L+ + EA V+ S+ +CL + +++ R NM + S ++ IQ+ Sbjct: 313 LQDQ-YSMEEACKVATLSL-RCLTTEIKL-----------RPNMSEVVSHLEHIQS 355
>CX32_ARATH (P27450) Probable serine/threonine-protein kinase Cx32, chloroplast| precursor (EC 2.7.11.1) Length = 419 Score = 60.8 bits (146), Expect = 4e-09 Identities = 43/173 (24%), Positives = 80/173 (46%), Gaps = 3/173 (1%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 +I+ D K SNILLD + A L DFG+A++ GP S + + Sbjct: 214 VIYRDFKASNILLDSNYDAKLSDFGLAKL----GPADEKSHVTTRIMGTYGYAAPEYMAT 269 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRPTDPMFTDGLD-IVNFVGSEF--PHQIHEVIDIYLK 426 G + DV++FG+VLLE++TG + G + +V+++ E H++ +++D +K Sbjct: 270 GHLYVKSDVFAFGVVLLEIMTGLTAHNTKRPRGQESLVDWLRPELSNKHRVKQIMDKGIK 329 Query: 425 GECEDSAEARSVSEGSVHQCLVSLLQVAVSCTHSIPSERANMRDAASKIQAIQ 267 G+ + + ++ +SC P R +M++ ++ IQ Sbjct: 330 GQ-------------YTTKVATEMARITLSCIEPDPKNRPHMKEVVEVLEHIQ 369
>CRI4_MAIZE (O24585) Putative receptor protein kinase CRINKLY4 precursor (EC| 2.7.11.1) Length = 901 Score = 59.7 bits (143), Expect = 1e-08 Identities = 33/93 (35%), Positives = 51/93 (54%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 +IH D+K SNIL+D+D A + DFG++ + GP + + S Sbjct: 630 VIHRDIKSSNILIDEDHNARVADFGLSIL----GPADSGTPLSELPAGTLGYLDPEYYRL 685 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRPTDPMFTDG 498 ++T DVYSFG+VLLE+L+G++ D F +G Sbjct: 686 HYLTTKSDVYSFGVVLLEILSGRKAIDMQFEEG 718
>APK1B_ARATH (P46573) Protein kinase APK1B, chloroplast precursor (EC 2.7.11.1)| Length = 412 Score = 59.7 bits (143), Expect = 1e-08 Identities = 34/87 (39%), Positives = 47/87 (54%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 +I+ D K SNILLD + A L DFG+A+ GP S S + Sbjct: 200 VIYRDFKTSNILLDSEYNAKLSDFGLAK----DGPTGDKSHVSTRIMGTYGYAAPEYLAT 255 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRPTD 516 G ++T DVYS+G+VLLE+L+G+R D Sbjct: 256 GHLTTKSDVYSYGVVLLEVLSGRRAVD 282
>IRAK1_MOUSE (Q62406) Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1)| (IRAK-1) (IRAK) (Pelle-like protein kinase) (mPLK) Length = 710 Score = 59.3 bits (142), Expect = 1e-08 Identities = 34/88 (38%), Positives = 52/88 (59%), Gaps = 4/88 (4%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIG----VRXXXXXXXXX 609 +IH D+K SN+LLD+ ++ LGDFG+AR +G + AS +S++ VR Sbjct: 336 LIHGDIKSSNVLLDERLMPKLGDFGLARFSRFAGAK-ASQSSTVARTSTVRGTLAYLPEE 394 Query: 608 XXXXGRISTSGDVYSFGIVLLEMLTGKR 525 GR++ D +SFG+V+LE L G+R Sbjct: 395 YIKTGRLAVDTDTFSFGVVILETLAGQR 422
>IRAK1_HUMAN (P51617) Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1)| (IRAK-1) Length = 712 Score = 58.9 bits (141), Expect = 2e-08 Identities = 33/87 (37%), Positives = 49/87 (56%), Gaps = 3/87 (3%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASST---SSIGVRXXXXXXXXXX 606 +IH D+K SN+LLD+ + LGDFG+AR +G P+ S+ + VR Sbjct: 336 LIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEY 395 Query: 605 XXXGRISTSGDVYSFGIVLLEMLTGKR 525 GR++ D +SFG+V+LE L G+R Sbjct: 396 IKTGRLAVDTDTFSFGVVVLETLAGQR 422
>SRK6_BRAOE (Q09092) Putative serine/threonine-protein kinase receptor| precursor (EC 2.7.11.1) (S-receptor kinase) (SRK) Length = 849 Score = 58.2 bits (139), Expect = 3e-08 Identities = 33/84 (39%), Positives = 49/84 (58%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 IIH DLK SNILLD +M+ + DFG+ARIF R + +++ V Sbjct: 649 IIHRDLKVSNILLDKNMIPKISDFGMARIF----ERDETEANTMKVVGTYGYMSPEYAMY 704 Query: 596 GRISTSGDVYSFGIVLLEMLTGKR 525 G S DV+SFG+++LE+++GK+ Sbjct: 705 GIFSEKSDVFSFGVIVLEIVSGKK 728
>PKNB_BIFLO (Q8G6P9) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 690 Score = 56.6 bits (135), Expect = 8e-08 Identities = 34/85 (40%), Positives = 43/85 (50%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 IIH D+KP NI++ + V + DFGIAR DS A+ T S GV Sbjct: 142 IIHRDIKPGNIMISEQGVVKVMDFGIARALDDSA---ATMTQSQGVVGTAQYLSPEQARG 198 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRP 522 + D+YS G VL EMLTG+ P Sbjct: 199 ETVDMRSDLYSAGCVLYEMLTGRPP 223
>PBS1_ARATH (Q9FE20) Serine/threonine-protein kinase PBS1 (EC 2.7.11.1)| (AvrPphB susceptible protein 1) Length = 456 Score = 56.2 bits (134), Expect = 1e-07 Identities = 33/93 (35%), Positives = 47/93 (50%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 +I+ D K SNILLD+ L DFG+A++ GP S S V Sbjct: 209 VIYRDFKSSNILLDEGFHPKLSDFGLAKL----GPTGDKSHVSTRVMGTYGYCAPEYAMT 264 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRPTDPMFTDG 498 G+++ DVYSFG+V LE++TG++ D G Sbjct: 265 GQLTVKSDVYSFGVVFLELITGRKAIDSEMPHG 297
>RLCK7_ARATH (Q9LQQ8) Probable serine/threonine-protein kinase RLCKVII (EC| 2.7.11.1) Length = 423 Score = 56.2 bits (134), Expect = 1e-07 Identities = 32/87 (36%), Positives = 48/87 (55%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 +I+ DLK SNILL +D L DFG+A++ GP + S V Sbjct: 226 VIYRDLKCSNILLGEDYQPKLSDFGLAKV----GPSGDKTHVSTRVMGTYGYCAPDYAMT 281 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRPTD 516 G+++ D+YSFG+VLLE++TG++ D Sbjct: 282 GQLTFKSDIYSFGVVLLELITGRKAID 308
>EPHB3_HUMAN (P54753) Ephrin type-B receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor HEK-2) Length = 998 Score = 55.8 bits (133), Expect = 1e-07 Identities = 32/104 (30%), Positives = 59/104 (56%), Gaps = 1/104 (0%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL NIL++ ++V + DFG++R FL+ P + TSS+G + Sbjct: 755 VHRDLAARNILVNSNLVCKVSDFGLSR-FLEDDPSDPTYTSSLGGKIPIRWTAPEAIAYR 813 Query: 593 RISTSGDVYSFGIVLLEMLT-GKRPTDPMFTDGLDIVNFVGSEF 465 + +++ DV+S+GIV+ E+++ G+RP M D++N V ++ Sbjct: 814 KFTSASDVWSYGIVMWEVMSYGERPYWDM--SNQDVINAVEQDY 855
>EPHB3_MOUSE (P54754) Ephrin type-B receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4) Length = 993 Score = 55.8 bits (133), Expect = 1e-07 Identities = 32/104 (30%), Positives = 59/104 (56%), Gaps = 1/104 (0%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL NIL++ ++V + DFG++R FL+ P + TSS+G + Sbjct: 750 VHRDLAARNILVNSNLVCKVSDFGLSR-FLEDDPSDPTYTSSLGGKIPIRWTAPEAIAYR 808 Query: 593 RISTSGDVYSFGIVLLEMLT-GKRPTDPMFTDGLDIVNFVGSEF 465 + +++ DV+S+GIV+ E+++ G+RP M D++N V ++ Sbjct: 809 KFTSASDVWSYGIVMWEVMSYGERPYWDM--SNQDVINAVEQDY 850
>EPHB3_CHICK (Q07498) Ephrin type-B receptor 3 (EC 2.7.10.1) (Tyrosine-protein| kinase receptor CEK10) (Fragment) Length = 988 Score = 55.8 bits (133), Expect = 1e-07 Identities = 32/104 (30%), Positives = 59/104 (56%), Gaps = 1/104 (0%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL NIL++ ++V + DFG++R FL+ P + TSS+G + Sbjct: 745 VHRDLAARNILVNSNLVCKVSDFGLSR-FLEDDPADPTYTSSLGGKIPIRWTAPEAIAYR 803 Query: 593 RISTSGDVYSFGIVLLEMLT-GKRPTDPMFTDGLDIVNFVGSEF 465 + +++ DV+S+GIV+ E+++ G+RP M D++N V ++ Sbjct: 804 KFTSASDVWSYGIVMWEVMSYGERPYWDM--SNQDVINAVEQDY 845
>IRAK4_HUMAN (Q9NWZ3) Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1)| (IRAK-4) (NY-REN-64 antigen) Length = 460 Score = 55.8 bits (133), Expect = 1e-07 Identities = 49/175 (28%), Positives = 80/175 (45%), Gaps = 4/175 (2%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 IH D+K +NILLD+ A + DFG+AR + + ++ +G G Sbjct: 308 IHRDIKSANILLDEAFTAKISDFGLARA-SEKFAQTVMTSRIVG----TTAYMAPEALRG 362 Query: 593 RISTSGDVYSFGIVLLEMLTGKRPTD----PMFTDGLDIVNFVGSEFPHQIHEVIDIYLK 426 I+ D+YSFG+VLLE++TG D P LDI + E + I+ Y+ Sbjct: 363 EITPKSDIYSFGVVLLEIITGLPAVDEHREPQLL--LDIKEEIEDE-----EKTIEDYID 415 Query: 425 GECEDSAEARSVSEGSVHQCLVSLLQVAVSCTHSIPSERANMRDAASKIQAIQAS 261 + D A++ SV ++ VA C H ++R +++ +Q + AS Sbjct: 416 KKMND-ADSTSVE---------AMYSVASQCLHEKKNKRPDIKKVQQLLQEMTAS 460
>MET_HUMAN (P08581) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1390 Score = 55.1 bits (131), Expect = 2e-07 Identities = 48/193 (24%), Positives = 77/193 (39%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL N +LD+ + DFG+AR D S + G + Sbjct: 1201 VHRDLAARNCMLDEKFTVKVADFGLARDMYDK--EYYSVHNKTGAKLPVKWMALESLQTQ 1258 Query: 593 RISTSGDVYSFGIVLLEMLTGKRPTDPMFTDGLDIVNFVGSEFPHQIHEVIDIYLKGECE 414 + +T DV+SFG+VL E++T P P D+ F I +YL Sbjct: 1259 KFTTKSDVWSFGVVLWELMTRGAPPYP------DVNTF-----------DITVYL----- 1296 Query: 413 DSAEARSVSEGSVHQCLVSLLQVAVSCTHSIPSERANMRDAASKIQAIQASYLGRQT*IL 234 + R + + C L +V + C H R + + S+I AI ++++G Sbjct: 1297 --LQGRRLLQ--PEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE----- 1347 Query: 233 QFNYVHTTTTYTS 195 +YVH TY + Sbjct: 1348 --HYVHVNATYVN 1358
>MET_OTOGA (Q2QLH6) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1382 Score = 54.7 bits (130), Expect = 3e-07 Identities = 47/193 (24%), Positives = 78/193 (40%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL N +LD++ + DFG+AR D S + G + Sbjct: 1202 VHRDLAARNCMLDENFTVKVADFGLARDMYDK--EYYSVHNKTGAKLPVKWMALESLQTQ 1259 Query: 593 RISTSGDVYSFGIVLLEMLTGKRPTDPMFTDGLDIVNFVGSEFPHQIHEVIDIYLKGECE 414 + +T DV+SFG++L E++T P P D+ F I +YL Sbjct: 1260 KFTTKSDVWSFGVLLWELMTRGAPPYP------DVNTF-----------DITVYL----- 1297 Query: 413 DSAEARSVSEGSVHQCLVSLLQVAVSCTHSIPSERANMRDAASKIQAIQASYLGRQT*IL 234 + R + + C L +V + C H R + + S+I AI ++++G Sbjct: 1298 --LQGRRLLQ--PEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE----- 1348 Query: 233 QFNYVHTTTTYTS 195 +YVH TY + Sbjct: 1349 --HYVHVNATYVN 1359
>MET_RAT (P97523) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1382 Score = 54.3 bits (129), Expect = 4e-07 Identities = 47/193 (24%), Positives = 79/193 (40%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL N +LD+ + DFG+AR D S + G + Sbjct: 1202 VHRDLAARNCMLDEKFTVKVADFGLARDMYDK--EYYSVHNKTGAKLPVKWMALESLQTQ 1259 Query: 593 RISTSGDVYSFGIVLLEMLTGKRPTDPMFTDGLDIVNFVGSEFPHQIHEVIDIYLKGECE 414 + +T DV+SFG++L E++T P P D+ F I IYL Sbjct: 1260 KFTTKSDVWSFGVLLWELMTRGAPPYP------DVNTF-----------DITIYL----- 1297 Query: 413 DSAEARSVSEGSVHQCLVSLLQVAVSCTHSIPSERANMRDAASKIQAIQASYLGRQT*IL 234 + R + + C +L +V + C H R ++ + S+I +I ++++G Sbjct: 1298 --LQGRRLLQ--PEYCPDALYEVMLKCWHPKAEMRPSVSELVSRISSIFSTFIGE----- 1348 Query: 233 QFNYVHTTTTYTS 195 +YVH TY + Sbjct: 1349 --HYVHVNATYVN 1359
>IRAK4_MOUSE (Q8R4K2) Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1)| (IRAK-4) Length = 459 Score = 54.3 bits (129), Expect = 4e-07 Identities = 51/172 (29%), Positives = 75/172 (43%), Gaps = 4/172 (2%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 IH D+K +NILLD D A + DFG+AR + R A + + + G Sbjct: 308 IHRDIKSANILLDKDFTAKISDFGLAR----ASARLAQTVMTSRI-VGTTAYMAPEALRG 362 Query: 593 RISTSGDVYSFGIVLLEMLTGKRPTD----PMFTDGLDIVNFVGSEFPHQIHEVIDIYLK 426 I+ D+YSFG+VLLE++TG D P LDI + E + I+ Y Sbjct: 363 EITPKSDIYSFGVVLLELITGLAAVDENREPQLL--LDIKEEIEDE-----EKTIEDYTD 415 Query: 425 GECEDSAEARSVSEGSVHQCLVSLLQVAVSCTHSIPSERANMRDAASKIQAI 270 + D A+ SV ++ A C H E+ N R +K+Q + Sbjct: 416 EKMSD-ADPASVE---------AMYSAASQCLH----EKKNRRPDIAKVQQL 453
>MET_PONPY (Q2IBD8) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1390 Score = 53.9 bits (128), Expect = 5e-07 Identities = 47/193 (24%), Positives = 77/193 (39%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL N +LD+ + DFG+AR D S + G + Sbjct: 1201 VHRDLAARNCMLDEKFTVKVADFGLARDMYDK--EYYSVHNKTGAKLPVKWMALESLQTQ 1258 Query: 593 RISTSGDVYSFGIVLLEMLTGKRPTDPMFTDGLDIVNFVGSEFPHQIHEVIDIYLKGECE 414 + +T DV+SFG++L E++T P P D+ F I +YL Sbjct: 1259 KFTTKSDVWSFGVLLWELMTRGAPPYP------DVNTF-----------DITVYL----- 1296 Query: 413 DSAEARSVSEGSVHQCLVSLLQVAVSCTHSIPSERANMRDAASKIQAIQASYLGRQT*IL 234 + R + + C L +V + C H R + + S+I AI ++++G Sbjct: 1297 --LQGRRLLQ--PEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE----- 1347 Query: 233 QFNYVHTTTTYTS 195 +YVH TY + Sbjct: 1348 --HYVHVNATYVN 1358
>MET_PANTR (Q2QLF1) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1390 Score = 53.9 bits (128), Expect = 5e-07 Identities = 47/193 (24%), Positives = 77/193 (39%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL N +LD+ + DFG+AR D S + G + Sbjct: 1201 VHRDLAARNCMLDEKFTVKVADFGLARDMYDK--EYYSVHNKTGAKLPVKWMALESLQTQ 1258 Query: 593 RISTSGDVYSFGIVLLEMLTGKRPTDPMFTDGLDIVNFVGSEFPHQIHEVIDIYLKGECE 414 + +T DV+SFG++L E++T P P D+ F I +YL Sbjct: 1259 KFTTKSDVWSFGVLLWELMTRGAPPYP------DVNTF-----------DITVYL----- 1296 Query: 413 DSAEARSVSEGSVHQCLVSLLQVAVSCTHSIPSERANMRDAASKIQAIQASYLGRQT*IL 234 + R + + C L +V + C H R + + S+I AI ++++G Sbjct: 1297 --LQGRRLLQ--PEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE----- 1347 Query: 233 QFNYVHTTTTYTS 195 +YVH TY + Sbjct: 1348 --HYVHVNATYVN 1358
>MET_CALMO (Q2QLC0) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1381 Score = 53.9 bits (128), Expect = 5e-07 Identities = 47/193 (24%), Positives = 77/193 (39%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL N +LD+ + DFG+AR D S + G + Sbjct: 1201 VHRDLAARNCMLDEKFTVKVADFGLARDMYDK--EYYSVHNKTGAKLPVKWMALESLQTQ 1258 Query: 593 RISTSGDVYSFGIVLLEMLTGKRPTDPMFTDGLDIVNFVGSEFPHQIHEVIDIYLKGECE 414 + +T DV+SFG++L E++T P P D+ F I +YL Sbjct: 1259 KFTTKSDVWSFGVLLWELMTRGAPPYP------DVNTF-----------DITVYL----- 1296 Query: 413 DSAEARSVSEGSVHQCLVSLLQVAVSCTHSIPSERANMRDAASKIQAIQASYLGRQT*IL 234 + R + + C L +V + C H R + + S+I AI ++++G Sbjct: 1297 --LQGRRLLQ--PEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE----- 1347 Query: 233 QFNYVHTTTTYTS 195 +YVH TY + Sbjct: 1348 --HYVHVNATYVN 1358
>MET_CALJA (Q2QLG5) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1381 Score = 53.9 bits (128), Expect = 5e-07 Identities = 47/193 (24%), Positives = 77/193 (39%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL N +LD+ + DFG+AR D S + G + Sbjct: 1201 VHRDLAARNCMLDEKFTVKVADFGLARDMYDK--EYYSVHNKTGAKLPVKWMALESLQTQ 1258 Query: 593 RISTSGDVYSFGIVLLEMLTGKRPTDPMFTDGLDIVNFVGSEFPHQIHEVIDIYLKGECE 414 + +T DV+SFG++L E++T P P D+ F I +YL Sbjct: 1259 KFTTKSDVWSFGVLLWELMTRGAPPYP------DVNTF-----------DITVYL----- 1296 Query: 413 DSAEARSVSEGSVHQCLVSLLQVAVSCTHSIPSERANMRDAASKIQAIQASYLGRQT*IL 234 + R + + C L +V + C H R + + S+I AI ++++G Sbjct: 1297 --LQGRRLLQ--PEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE----- 1347 Query: 233 QFNYVHTTTTYTS 195 +YVH TY + Sbjct: 1348 --HYVHVNATYVN 1358
>MET_MOUSE (P16056) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1379 Score = 53.9 bits (128), Expect = 5e-07 Identities = 47/193 (24%), Positives = 78/193 (40%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL N +LD+ + DFG+AR D S + G + Sbjct: 1199 VHRDLAARNCMLDEKFTVKVADFGLARDMYDK--EYYSVHNKTGAKLPVKWMALESLQTQ 1256 Query: 593 RISTSGDVYSFGIVLLEMLTGKRPTDPMFTDGLDIVNFVGSEFPHQIHEVIDIYLKGECE 414 + +T DV+SFG++L E++T P P D+ F I IYL Sbjct: 1257 KFTTKSDVWSFGVLLWELMTRGAPPYP------DVNTF-----------DITIYL----- 1294 Query: 413 DSAEARSVSEGSVHQCLVSLLQVAVSCTHSIPSERANMRDAASKIQAIQASYLGRQT*IL 234 + R + + C +L +V + C H R + + S+I +I ++++G Sbjct: 1295 --LQGRRLLQ--PEYCPDALYEVMLKCWHPKAEMRPSFSELVSRISSIFSTFIGE----- 1345 Query: 233 QFNYVHTTTTYTS 195 +YVH TY + Sbjct: 1346 --HYVHVNATYVN 1356
>PKN5_MYXXA (P54737) Serine/threonine-protein kinase pkn5 (EC 2.7.11.1)| Length = 380 Score = 53.9 bits (128), Expect = 5e-07 Identities = 29/87 (33%), Positives = 45/87 (51%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 ++H DLKPSNI++DDD L DFG+A+ D A+ T + + Sbjct: 240 LVHRDLKPSNIMVDDDRQVRLMDFGLAKFLADD----AAITEAGKLVGTYRYMAPEQILG 295 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRPTD 516 + D+YS G++L E+L+G+ P D Sbjct: 296 EPLDGRADLYSLGVILYELLSGRPPFD 322
>MET_MICMU (Q2QL89) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1382 Score = 53.9 bits (128), Expect = 5e-07 Identities = 47/193 (24%), Positives = 77/193 (39%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL N +LD+ + DFG+AR D S + G + Sbjct: 1202 VHRDLAARNCMLDEKFTVKVADFGLARDMYDK--EYYSVHNKTGAKLPVKWMALESLQTQ 1259 Query: 593 RISTSGDVYSFGIVLLEMLTGKRPTDPMFTDGLDIVNFVGSEFPHQIHEVIDIYLKGECE 414 + +T DV+SFG++L E++T P P D+ F I +YL Sbjct: 1260 KFTTKSDVWSFGVLLWELMTRGAPPYP------DVNTF-----------DITVYL----- 1297 Query: 413 DSAEARSVSEGSVHQCLVSLLQVAVSCTHSIPSERANMRDAASKIQAIQASYLGRQT*IL 234 + R + + C L +V + C H R + + S+I AI ++++G Sbjct: 1298 --LQGRRLLQ--PEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE----- 1348 Query: 233 QFNYVHTTTTYTS 195 +YVH TY + Sbjct: 1349 --HYVHVNATYVN 1359
>PKN2_CLOAB (Q97IC2) Probable serine/threonine protein kinase CAC1728 (EC| 2.7.11.1) Length = 657 Score = 53.9 bits (128), Expect = 5e-07 Identities = 32/87 (36%), Positives = 45/87 (51%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 I+H D+KP NI++ DD + + DFGIA+ +S + T++ V Sbjct: 129 IVHRDIKPHNIMVTDDDIIKVTDFGIAKASNES-----TITTTNKVVGSAHYLSPEQAQG 183 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRPTD 516 + D+YSFGIVL EM TGK P D Sbjct: 184 IPVDCRTDIYSFGIVLYEMATGKVPYD 210
>MET_HORSE (Q2QLA9) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1381 Score = 53.5 bits (127), Expect = 7e-07 Identities = 47/193 (24%), Positives = 77/193 (39%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL N +LD+ + DFG+AR D S + G + Sbjct: 1201 VHRDLAARNCMLDEKFTVKVADFGLARDMYDK--EYYSVHNKTGAKLPVKWMALESLQTQ 1258 Query: 593 RISTSGDVYSFGIVLLEMLTGKRPTDPMFTDGLDIVNFVGSEFPHQIHEVIDIYLKGECE 414 + +T DV+SFG++L E++T P P D+ F I +YL Sbjct: 1259 KFTTKSDVWSFGVLLWELMTRGAPPYP------DVNTF-----------DITVYL----- 1296 Query: 413 DSAEARSVSEGSVHQCLVSLLQVAVSCTHSIPSERANMRDAASKIQAIQASYLGRQT*IL 234 + R + + C L +V + C H R + + S+I AI ++++G Sbjct: 1297 --LQGRRLLQ--PEYCPDPLYEVMLKCWHPKAELRPSFSELVSRISAIFSTFIGE----- 1347 Query: 233 QFNYVHTTTTYTS 195 +YVH TY + Sbjct: 1348 --HYVHVNATYVN 1358
>EPHB3_BRARE (O13147) Ephrin type-B receptor 3 (EC 2.7.10.1) (Tyrosine-protein| kinase receptor ZEK3) (EPH-like kinase 3) (Fragment) Length = 500 Score = 53.5 bits (127), Expect = 7e-07 Identities = 31/104 (29%), Positives = 58/104 (55%), Gaps = 1/104 (0%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL N+L++ ++V + DFG++R FLD + TSS+G + Sbjct: 309 VHRDLAARNVLVNSNLVCKVSDFGLSR-FLDDNSSDPTYTSSLGGKIPIRWTAPEAIAFR 367 Query: 593 RISTSGDVYSFGIVLLEMLT-GKRPTDPMFTDGLDIVNFVGSEF 465 + +++ DV+S+GIV+ E+++ G+RP M D++N V ++ Sbjct: 368 KFTSASDVWSYGIVMWEVMSFGERPYWDM--SNQDVMNAVEQDY 409
>MET_CANFA (Q75ZY9) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1382 Score = 53.5 bits (127), Expect = 7e-07 Identities = 47/193 (24%), Positives = 77/193 (39%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL N +LD+ + DFG+AR D S + G + Sbjct: 1202 VHRDLAARNCMLDEKFTVKVADFGLARDMYDK--EYYSVHNKTGAKLPVKWMALESLQTQ 1259 Query: 593 RISTSGDVYSFGIVLLEMLTGKRPTDPMFTDGLDIVNFVGSEFPHQIHEVIDIYLKGECE 414 + +T DV+SFG++L E++T P P D+ F I +YL Sbjct: 1260 KFTTKSDVWSFGVLLWELMTRGAPPYP------DVNTF-----------DITVYL----- 1297 Query: 413 DSAEARSVSEGSVHQCLVSLLQVAVSCTHSIPSERANMRDAASKIQAIQASYLGRQT*IL 234 + R + + C L +V + C H R + + S+I AI ++++G Sbjct: 1298 --LQGRRLLQ--PEYCPDPLYEVMLKCWHPRAELRPSFSELVSRISAIFSTFIGE----- 1348 Query: 233 QFNYVHTTTTYTS 195 +YVH TY + Sbjct: 1349 --HYVHVNATYVN 1359
>PKN1_THETN (Q8R9T6) Probable serine/threonine-protein kinase Sps1 (EC| 2.7.11.1) Length = 625 Score = 53.5 bits (127), Expect = 7e-07 Identities = 34/85 (40%), Positives = 42/85 (49%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 IIH D+KP NIL+ D+ V + DFGIAR A+ T + V Sbjct: 130 IIHRDIKPQNILVTDEDVVKVTDFGIAR-----AANGATITYTGDVIGTAYYFSPEQAKG 184 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRP 522 + D+YS GIVL EMLTGK P Sbjct: 185 SIVDERTDIYSLGIVLFEMLTGKVP 209
>KSG1_SCHPO (Q12701) Serine/threonine-protein kinase ksg1 (EC 2.7.11.1)| Length = 592 Score = 53.1 bits (126), Expect = 9e-07 Identities = 42/133 (31%), Positives = 59/133 (44%), Gaps = 16/133 (12%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDS----------GPRP-ASSTSSIGVRXX 630 +IH DLKP NILLDD+M + DFG A+I S +P A S S +G Sbjct: 219 VIHRDLKPENILLDDNMRTKITDFGSAKILNSSHGSHEEDTHHADKPQAHSRSFVGTARY 278 Query: 629 XXXXXXXXXXXGRISTSGDVYSFGIVLLEMLTGKRPTDPMFTDGLDIVNF-----VGSEF 465 T+ D+++FG +L +ML GK P F G + + F + E Sbjct: 279 VSPEVLSDKIA---GTASDIWAFGCILFQMLAGK----PPFVAGNEYLTFQSILHLSYEI 331 Query: 464 PHQIHEVIDIYLK 426 P I +V +K Sbjct: 332 PPDISDVASDLIK 344
>MET_PIG (Q2QLE0) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1381 Score = 53.1 bits (126), Expect = 9e-07 Identities = 47/193 (24%), Positives = 77/193 (39%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL N +LD+ + DFG+AR D S + G + Sbjct: 1201 VHRDLAARNCMLDEKFTVKVADFGLARDVYDK--EYYSVHNKTGAKLPVKWMALESLQTQ 1258 Query: 593 RISTSGDVYSFGIVLLEMLTGKRPTDPMFTDGLDIVNFVGSEFPHQIHEVIDIYLKGECE 414 + +T DV+SFG++L E++T P P D+ F I +YL Sbjct: 1259 KFTTKSDVWSFGVLLWELMTRGAPPYP------DVNTF-----------DITVYL----- 1296 Query: 413 DSAEARSVSEGSVHQCLVSLLQVAVSCTHSIPSERANMRDAASKIQAIQASYLGRQT*IL 234 + R + + C L +V + C H R + + S+I AI ++++G Sbjct: 1297 --LQGRRLLQ--PEYCPDPLYEVMLKCWHPRAELRPSFSELVSRISAIFSTFIGE----- 1347 Query: 233 QFNYVHTTTTYTS 195 +YVH TY + Sbjct: 1348 --HYVHVNATYVN 1358
>PKNB_MYCTU (P0A5S4) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 626 Score = 53.1 bits (126), Expect = 9e-07 Identities = 32/85 (37%), Positives = 41/85 (48%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 IIH D+KP+NI++ + DFGIAR DSG S T + V Sbjct: 134 IIHRDVKPANIMISATNAVKVMDFGIARAIADSG---NSVTQTAAVIGTAQYLSPEQARG 190 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRP 522 + DVYS G VL E+LTG+ P Sbjct: 191 DSVDARSDVYSLGCVLYEVLTGEPP 215
>PKNB_MYCBO (P0A5S5) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 626 Score = 53.1 bits (126), Expect = 9e-07 Identities = 32/85 (37%), Positives = 41/85 (48%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 IIH D+KP+NI++ + DFGIAR DSG S T + V Sbjct: 134 IIHRDVKPANIMISATNAVKVMDFGIARAIADSG---NSVTQTAAVIGTAQYLSPEQARG 190 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRP 522 + DVYS G VL E+LTG+ P Sbjct: 191 DSVDARSDVYSLGCVLYEVLTGEPP 215
>EPHB5_CHICK (Q07497) Ephrin type-B receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase CEK9) Length = 1002 Score = 52.4 bits (124), Expect = 2e-06 Identities = 29/104 (27%), Positives = 56/104 (53%), Gaps = 1/104 (0%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL NIL++ ++V + DFG++R D P + T ++G + Sbjct: 759 VHRDLAARNILVNSNLVCKVSDFGLSRFLEDDASNP-TYTGALGCKIPIRWTAPEAVQYR 817 Query: 593 RISTSGDVYSFGIVLLEMLT-GKRPTDPMFTDGLDIVNFVGSEF 465 + ++S DV+S+GIV+ E+++ G+RP M D++N + ++ Sbjct: 818 KFTSSSDVWSYGIVMWEVMSYGERPYWDM--SNQDVINAIDQDY 859
>EPHB3_XENLA (Q91735) Ephrin type-B receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor TCK) Length = 974 Score = 52.4 bits (124), Expect = 2e-06 Identities = 33/126 (26%), Positives = 69/126 (54%), Gaps = 10/126 (7%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL NIL++ ++V + DFG++R FL++ + TS++G + Sbjct: 731 VHRDLAARNILVNSNLVCKVSDFGLSR-FLENSRSDPTYTSALGGKIPIRWTAPEAISYR 789 Query: 593 RISTSGDVYSFGIVLLEMLT-GKRPTDPMFTDGLDIVNFVGSEF--------PHQIHE-V 444 + +++ DV+S+GIV+ E+++ G+RP M D++N + ++ P +H+ + Sbjct: 790 KFTSASDVWSYGIVMWEVMSYGERPYWDM--SNQDVINAIEQDYRLPPPMDCPSALHQLM 847 Query: 443 IDIYLK 426 +D +L+ Sbjct: 848 LDCWLR 853
>YR831_MIMIV (Q7T6Y2) Putative serine/threonine-protein kinase/receptor R831| precursor (EC 2.7.11.1) Length = 1624 Score = 52.4 bits (124), Expect = 2e-06 Identities = 36/118 (30%), Positives = 54/118 (45%), Gaps = 6/118 (5%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 I+H D+KP+NIL+D+ + DFG ARI D+ T Sbjct: 1483 IVHRDIKPANILVDEHFNVKIADFGFARIKEDNTTMTRCGTPC--------WTAPEVIRG 1534 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRPTDP--MFTDGLDIVN----FVGSEFPHQIHEVI 441 + DV+SFG+V+ E+LTGK P LDI+ + S+ PH+ ++I Sbjct: 1535 EKYCEKADVFSFGVVMWEVLTGKEPFAECNFMKVSLDILEGGRPIIPSDCPHEFAKLI 1592 Score = 40.4 bits (93), Expect = 0.006 Identities = 25/85 (29%), Positives = 39/85 (45%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 I+H DLK N+LLD + DFG+ ++ + + + + Sbjct: 904 IVHRDLKSLNLLLDSKWNVKVSDFGLTKVKSELDKKKTNDNIIGTIHWIAPEILNDSTEV 963 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRP 522 I DVYSFGI+L E+LT ++P Sbjct: 964 DYI--LADVYSFGIILWELLTREQP 986
>RON_MOUSE (Q62190) Macrophage-stimulating protein receptor precursor (EC| 2.7.10.1) (MSP receptor) (p185-Ron) (Stem cell-derived tyrosine kinase) (CDw136 antigen) [Contains: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating prote Length = 1378 Score = 52.4 bits (124), Expect = 2e-06 Identities = 49/193 (25%), Positives = 74/193 (38%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL N +LD+ + DFG+AR LD S R Sbjct: 1182 VHRDLAARNCMLDESFTVKVADFGLARGVLDK--EYYSVRQHRHARLPVKWMALESLQTY 1239 Query: 593 RISTSGDVYSFGIVLLEMLTGKRPTDPMFTDGLDIVNFVGSEFPHQIHEVIDIYLKGECE 414 R +T DV+SFG++L E+LT P P D D+ +F+ Sbjct: 1240 RFTTKSDVWSFGVLLWELLTRGAPPYP-HIDPFDLSHFL--------------------- 1277 Query: 413 DSAEARSVSEGSVHQCLVSLLQVAVSCTHSIPSERANMRDAASKIQAIQASYLGRQT*IL 234 A+ R + + C SL V + C + P+ R R +++ + AS LG Sbjct: 1278 --AQGRRLPQ--PEYCPDSLYHVMLRCWEADPAARPTFRALVLEVKQVVASLLGD----- 1328 Query: 233 QFNYVHTTTTYTS 195 +YV T Y + Sbjct: 1329 --HYVQLTAAYVN 1339
>EPB1A_XENLA (Q91571) Ephrin type-B receptor 1-A precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor XEK) Length = 985 Score = 52.0 bits (123), Expect = 2e-06 Identities = 30/104 (28%), Positives = 57/104 (54%), Gaps = 1/104 (0%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL NIL++ ++V + DFG++R D P + TSS+G + Sbjct: 742 VHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDP-TYTSSLGGKIPVRWTAQEAIAYR 800 Query: 593 RISTSGDVYSFGIVLLEMLT-GKRPTDPMFTDGLDIVNFVGSEF 465 + +++ DV+S+GIV+ E+++ G+RP M D++N + ++ Sbjct: 801 KFTSASDVWSYGIVMWEVMSYGERPYWTM--SNQDVINAIEQDY 842
>EPHB4_MOUSE (P54761) Ephrin type-B receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor MDK-2) (Developmental kinase 2) (Tyrosine kinase MYK-1) Length = 987 Score = 52.0 bits (123), Expect = 2e-06 Identities = 29/104 (27%), Positives = 57/104 (54%), Gaps = 1/104 (0%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL NIL++ ++V + DFG++R FL+ + TSS+G + Sbjct: 737 VHRDLAARNILVNSNLVCKVSDFGLSR-FLEENSSDPTYTSSLGGKISIRWTAPEAIAFR 795 Query: 593 RISTSGDVYSFGIVLLEMLT-GKRPTDPMFTDGLDIVNFVGSEF 465 + +++ D +S+GIV+ E+++ G+RP M D++N + ++ Sbjct: 796 KFTSASDAWSYGIVMWEVMSFGERPYWDM--SNQDVINAIEQDY 837
>ANKK1_MOUSE (Q8BZ25) Ankyrin repeat and protein kinase domain-containing| protein 1 (EC 2.7.11.1) Length = 745 Score = 52.0 bits (123), Expect = 2e-06 Identities = 33/123 (26%), Positives = 58/123 (47%), Gaps = 9/123 (7%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 ++H DLKP NILLD++M + DFG+++ S + S++ Sbjct: 153 LLHLDLKPGNILLDNNMHVKISDFGLSKWMEQSTQKQYIERSALRGTLSYIPPEMFLENN 212 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRPTDPMFTDGLDI---------VNFVGSEFPHQIHEV 444 DVYSF IV+ E+LT K+P + + I + V E+P ++H++ Sbjct: 213 KAPGPEYDVYSFAIVIWEILTQKKPYAGLNMMTIIIRVAAGMRPSLQDVSDEWPEEVHQM 272 Query: 443 IDI 435 +++ Sbjct: 273 VNL 275
>EPHB1_RAT (P09759) Ephrin type-B receptor 1 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-2) (ELK) Length = 984 Score = 51.6 bits (122), Expect = 3e-06 Identities = 30/104 (28%), Positives = 57/104 (54%), Gaps = 1/104 (0%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL NIL++ ++V + DFG++R D P + TSS+G + Sbjct: 741 VHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDP-TYTSSLGGKIPVRWTAPEAIAYR 799 Query: 593 RISTSGDVYSFGIVLLEMLT-GKRPTDPMFTDGLDIVNFVGSEF 465 + +++ DV+S+GIV+ E+++ G+RP M D++N + ++ Sbjct: 800 KFTSASDVWSYGIVMWEVMSFGERPYWDM--SNQDVINAIEQDY 841
>EPHB1_HUMAN (P54762) Ephrin type-B receptor 1 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK) Length = 984 Score = 51.6 bits (122), Expect = 3e-06 Identities = 30/104 (28%), Positives = 57/104 (54%), Gaps = 1/104 (0%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL NIL++ ++V + DFG++R D P + TSS+G + Sbjct: 741 VHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDP-TYTSSLGGKIPVRWTAPEAIAYR 799 Query: 593 RISTSGDVYSFGIVLLEMLT-GKRPTDPMFTDGLDIVNFVGSEF 465 + +++ DV+S+GIV+ E+++ G+RP M D++N + ++ Sbjct: 800 KFTSASDVWSYGIVMWEVMSFGERPYWDM--SNQDVINAIEQDY 841
>EPHB1_CHICK (Q07494) Ephrin type-B receptor 1 (EC 2.7.10.1) (Tyrosine-protein| kinase receptor EPH-2) (Tyrosine kinase CEK6 receptor) (Fragment) Length = 984 Score = 51.6 bits (122), Expect = 3e-06 Identities = 30/104 (28%), Positives = 57/104 (54%), Gaps = 1/104 (0%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL NIL++ ++V + DFG++R D P + TSS+G + Sbjct: 741 VHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDP-TYTSSLGGKIPVRWTAPEAIAYR 799 Query: 593 RISTSGDVYSFGIVLLEMLT-GKRPTDPMFTDGLDIVNFVGSEF 465 + +++ DV+S+GIV+ E+++ G+RP M D++N + ++ Sbjct: 800 KFTSASDVWSYGIVMWEVMSFGERPYWDM--SNQDVINAIEQDY 841
>EPHB2_CHICK (P28693) Ephrin type-B receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor CEK5) Length = 1004 Score = 51.6 bits (122), Expect = 3e-06 Identities = 31/120 (25%), Positives = 65/120 (54%), Gaps = 9/120 (7%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL NIL++ ++V + DFG++R FL+ + TS++G + Sbjct: 761 VHRDLAARNILVNSNLVCKVSDFGLSR-FLEDDTSDPTYTSALGGKIPIRWTAPEAIQYR 819 Query: 593 RISTSGDVYSFGIVLLEMLT-GKRPTDPMFTDGLDIVNFVGSEF--------PHQIHEVI 441 + +++ DV+S+GIV+ E+++ G+RP M D++N + ++ P+ +H+++ Sbjct: 820 KFTSASDVWSYGIVMWEVMSYGERPYWDMTNQ--DVINAIEQDYRLPPPMDCPNALHQLM 877
>TMKL1_ARATH (P33543) Putative kinase-like protein TMKL1 precursor| Length = 674 Score = 51.2 bits (121), Expect = 4e-06 Identities = 42/171 (24%), Positives = 78/171 (45%), Gaps = 4/171 (2%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDS-GPRPASSTSSIGVRXXXXXXXXXXXX 600 IIH +++ N+L+DD A L +FG+ +I + + S S G + Sbjct: 496 IIHGNIRSKNVLVDDFFFARLTEFGLDKIMVQAVADEIVSQAKSDGYKAPELHKMK---- 551 Query: 599 XGRISTSGDVYSFGIVLLEMLTGKRP--TDPMFTDGLDIVNFV-GSEFPHQIHEVIDIYL 429 + + DVY+FGI+LLE+L GK+P + + +D+ + V + EV D+ Sbjct: 552 --KCNPRSDVYAFGILLLEILMGKKPGKSGRNGNEFVDLPSLVKAAVLEETTMEVFDL-- 607 Query: 428 KGECEDSAEARSVSEGSVHQCLVSLLQVAVSCTHSIPSERANMRDAASKIQ 276 EA + + LV L++A+ C + + R +M + +++ Sbjct: 608 --------EAMKGIRSPMEEGLVHALKLAMGCCAPVTTVRPSMEEVVKQLE 650
>RIPK3_HUMAN (Q9Y572) Receptor-interacting serine/threonine-protein kinase 3 (EC| 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) Length = 518 Score = 51.2 bits (121), Expect = 4e-06 Identities = 29/91 (31%), Positives = 46/91 (50%), Gaps = 3/91 (3%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 ++H DLKPSN+L D ++ L DFG++ G + + + G Sbjct: 138 LLHRDLKPSNVLPDPELHVKLADFGLST--FQGGSQSGTGSGEPGGTLGYLAPELFVNVN 195 Query: 596 GRISTSGDVYSFGIVLLEMLTGKR---PTDP 513 + ST+ DVYSFGI++ +L G+ PT+P Sbjct: 196 RKASTASDVYSFGILMWAVLAGREVELPTEP 226
>PKNB_MYCLE (P54744) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 622 Score = 51.2 bits (121), Expect = 4e-06 Identities = 31/85 (36%), Positives = 40/85 (47%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 IIH D+KP+NI++ + DFGIAR DS S T + V Sbjct: 134 IIHRDVKPANIMISATNAVKVMDFGIARAIADS----TSVTQTAAVIGTAQYLSPEQARG 189 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRP 522 + DVYS G VL E+LTG+ P Sbjct: 190 DSVDARSDVYSLGCVLYEILTGEPP 214
>EPB1B_XENLA (Q91736) Ephrin type-B receptor 1-B (EC 2.7.10.1) (Tyrosine-protein| kinase receptor XELK) (Fragment) Length = 902 Score = 51.2 bits (121), Expect = 4e-06 Identities = 30/104 (28%), Positives = 57/104 (54%), Gaps = 1/104 (0%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL NIL++ ++V + DFG++R D P + TSS+G + Sbjct: 659 VHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDP-TYTSSLGGKIPVRWTAPEAIRYR 717 Query: 593 RISTSGDVYSFGIVLLEMLT-GKRPTDPMFTDGLDIVNFVGSEF 465 + +++ DV+S+GIV+ E+++ G+RP M D++N + ++ Sbjct: 718 KFTSASDVWSYGIVMWEVMSYGERPYWDM--SNQDVINAIEQDY 759
>ANKK1_HUMAN (Q8NFD2) Ankyrin repeat and protein kinase domain-containing| protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288) Length = 765 Score = 51.2 bits (121), Expect = 4e-06 Identities = 45/181 (24%), Positives = 78/181 (43%), Gaps = 11/181 (6%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 ++H DLKP NILLD +M + DFG+++ S S++ Sbjct: 141 LLHLDLKPGNILLDSNMHVKISDFGLSKWMEQSTRMQYIERSALRGMLSYIPPEMFLESN 200 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRPTDPMFTDGLDIVNF----------VGSEFPHQIHE 447 DVYSF IV+ E+LT K+P F + I+ V ++P + + Sbjct: 201 KAPGPKYDVYSFAIVIWELLTQKKPYSG-FNMMMIIIRVAAGMRPSLQPVSDQWPSEAQQ 259 Query: 446 VIDIYLKGECEDSAEARSVSEGSVH-QCLVSLLQVAVSCTHSIPSERANMRDAASKIQAI 270 ++D+ + +D + + ++ L+SLLQ V ++P +A R + K+ Sbjct: 260 MVDLMKRCWDQDPKKRPCFLDITIETDILLSLLQSRV----AVPESKALARKVSCKLSLR 315 Query: 269 Q 267 Q Sbjct: 316 Q 316
>EPHB4_HUMAN (P54760) Ephrin type-B receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor HTK) Length = 987 Score = 51.2 bits (121), Expect = 4e-06 Identities = 29/104 (27%), Positives = 57/104 (54%), Gaps = 1/104 (0%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL NIL++ ++V + DFG++R FL+ + TSS+G + Sbjct: 737 VHRDLAARNILVNSNLVCKVSDFGLSR-FLEENSSDPTYTSSLGGKIPIRWTAPEAIAFR 795 Query: 593 RISTSGDVYSFGIVLLEMLT-GKRPTDPMFTDGLDIVNFVGSEF 465 + +++ D +S+GIV+ E+++ G+RP M D++N + ++ Sbjct: 796 KFTSASDAWSYGIVMWEVMSFGERPYWDM--SNQDVINAIEQDY 837
>EPHB2_HUMAN (P29323) Ephrin type-B receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen) Length = 1055 Score = 50.8 bits (120), Expect = 5e-06 Identities = 29/104 (27%), Positives = 58/104 (55%), Gaps = 1/104 (0%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL NIL++ ++V + DFG++R FL+ + TS++G + Sbjct: 743 VHRDLAARNILVNSNLVCKVSDFGLSR-FLEDDTSDPTYTSALGGKIPIRWTAPEAIQYR 801 Query: 593 RISTSGDVYSFGIVLLEMLT-GKRPTDPMFTDGLDIVNFVGSEF 465 + +++ DV+S+GIV+ E+++ G+RP M D++N + ++ Sbjct: 802 KFTSASDVWSYGIVMWEVMSYGERPYWDMTNQ--DVINAIEQDY 843
>PKN2_MYXXA (P54736) Serine/threonine-protein kinase pkn2 (EC 2.7.11.1)| Length = 830 Score = 50.8 bits (120), Expect = 5e-06 Identities = 34/91 (37%), Positives = 45/91 (49%), Gaps = 4/91 (4%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDM---VAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXX-X 609 IIH DLKP N+ + A L DFGIAR+ P ASS S IGV Sbjct: 131 IIHRDLKPENVFISKSARGEQARLLDFGIARLV---EPDAASSVSQIGVVLGTPEYLSPE 187 Query: 608 XXXXGRISTSGDVYSFGIVLLEMLTGKRPTD 516 ++ T D+YSFG++ +L+G+ P D Sbjct: 188 QAVGAKVDTRSDLYSFGVLTYRVLSGRLPFD 218
>EPHB2_MOUSE (P54763) Ephrin type-B receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3) Length = 994 Score = 50.8 bits (120), Expect = 5e-06 Identities = 29/104 (27%), Positives = 58/104 (55%), Gaps = 1/104 (0%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL NIL++ ++V + DFG++R FL+ + TS++G + Sbjct: 751 VHRDLAARNILVNSNLVCKVSDFGLSR-FLEDDTSDPTYTSALGGKIPIRWTAPEAIQYR 809 Query: 593 RISTSGDVYSFGIVLLEMLT-GKRPTDPMFTDGLDIVNFVGSEF 465 + +++ DV+S+GIV+ E+++ G+RP M D++N + ++ Sbjct: 810 KFTSASDVWSYGIVMWEVMSYGERPYWDMTNQ--DVINAIEQDY 851
>YES_CHICK (P09324) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 540 Score = 50.4 bits (119), Expect = 6e-06 Identities = 30/87 (34%), Positives = 46/87 (52%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 IH DL+ +NIL+ D++V + DFG+AR+ D+ T+ G + G Sbjct: 390 IHRDLRAANILVGDNLVCKIADFGLARLIEDN-----EYTARQGAKFPIKWTAPEAALYG 444 Query: 593 RISTSGDVYSFGIVLLEMLTGKRPTDP 513 R + DV+SFGI+L E++T R P Sbjct: 445 RFTIKSDVWSFGILLTELVTKGRVPYP 471
>YES_AVISY (P00527) Tyrosine-protein kinase transforming protein YES (EC| 2.7.10.2) (Fragment) Length = 528 Score = 50.4 bits (119), Expect = 6e-06 Identities = 30/87 (34%), Positives = 46/87 (52%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 IH DL+ +NIL+ D++V + DFG+AR+ D+ T+ G + G Sbjct: 383 IHRDLRAANILVGDNLVCKIADFGLARLIEDN-----EYTARQGAKFPIKWTAPEAALYG 437 Query: 593 RISTSGDVYSFGIVLLEMLTGKRPTDP 513 R + DV+SFGI+L E++T R P Sbjct: 438 RFTIKSDVWSFGILLTELVTKGRVPYP 464
>FYN_XIPHE (P27446) Proto-oncogene tyrosine-protein kinase FYN (EC 2.7.10.2)| (P59-FYN) Length = 536 Score = 50.4 bits (119), Expect = 6e-06 Identities = 30/87 (34%), Positives = 46/87 (52%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 IH DL+ +NIL+ D++V + DFG+AR+ D+ T+ G + G Sbjct: 386 IHRDLRSANILVGDNLVCKIADFGLARLIEDN-----EYTARQGAKFPIKWTAPEAALYG 440 Query: 593 RISTSGDVYSFGIVLLEMLTGKRPTDP 513 R + DV+SFGI+L E++T R P Sbjct: 441 RFTIKSDVWSFGILLTELVTKGRVPYP 467
>EPHA8_HUMAN (P29322) Ephrin type-A receptor 8 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase) (HEK3) Length = 1005 Score = 50.4 bits (119), Expect = 6e-06 Identities = 32/120 (26%), Positives = 61/120 (50%), Gaps = 9/120 (7%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL N+L+D ++V + DFG++R+ D P ++ ++ G + Sbjct: 757 VHRDLAARNVLVDSNLVCKVSDFGLSRVLEDD---PDAAYTTTGGKIPIRWTAPEAIAFR 813 Query: 593 RISTSGDVYSFGIVLLEMLT-GKRPTDPMFTDGLDIVNFVGSEF--------PHQIHEVI 441 S++ DV+SFG+V+ E+L G+RP M D+++ V + PH +H+++ Sbjct: 814 TFSSASDVWSFGVVMWEVLAYGERPYWNM--TNRDVISSVEEGYRLPAPMGCPHALHQLM 871
>BMX_HUMAN (P51813) Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2)| (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38) Length = 675 Score = 50.4 bits (119), Expect = 6e-06 Identities = 42/174 (24%), Positives = 70/174 (40%), Gaps = 5/174 (2%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 IH DL N L+D D+ + DFG+ R LD SS+G + Sbjct: 533 IHRDLAARNCLVDRDLCVKVSDFGMTRYVLDD-----QYVSSVGTKFPVKWSAPEVFHYF 587 Query: 593 RISTSGDVYSFGIVLLEMLT-GKRPTDPMFTDGLDIVNFVGSEFPHQIHEVIDIYLKGEC 417 + S+ DV++FGI++ E+ + GK+P D+Y Sbjct: 588 KYSSKSDVWAFGILMWEVFSLGKQP--------------------------YDLY----- 616 Query: 416 EDSAEARSVSEG----SVHQCLVSLLQVAVSCTHSIPSERANMRDAASKIQAIQ 267 ++S VS+G H ++ Q+ SC H +P +R + S I+ ++ Sbjct: 617 DNSQVVLKVSQGHRLYRPHLASDTIYQIMYSCWHELPEKRPTFQQLLSSIEPLR 670
>BMX_MOUSE (P97504) Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2)| (Bone marrow tyrosine kinase gene in chromosome X protein homolog) Length = 651 Score = 50.1 bits (118), Expect = 8e-06 Identities = 42/170 (24%), Positives = 70/170 (41%), Gaps = 1/170 (0%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 IH DL N L+D D+ + DFG+ R LD SS+G + Sbjct: 509 IHRDLAARNCLVDSDLSVKVSDFGMTRYVLDD-----QYVSSVGTKFPVKWSAPEVFHYF 563 Query: 593 RISTSGDVYSFGIVLLEMLT-GKRPTDPMFTDGLDIVNFVGSEFPHQIHEVIDIYLKGEC 417 + S+ DV++FGI++ E+ + GK+P D D ++V V Q H + L + Sbjct: 564 KYSSKSDVWAFGILMWEVFSLGKQPYD--LYDNSEVVVKVS-----QGHRLYRPQLASD- 615 Query: 416 EDSAEARSVSEGSVHQCLVSLLQVAVSCTHSIPSERANMRDAASKIQAIQ 267 ++ Q+ SC H +P +R + S I+ ++ Sbjct: 616 -------------------TIYQIMYSCWHELPEKRPTFQQLLSAIEPLR 646
>YES_XIPHE (P27447) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 543 Score = 50.1 bits (118), Expect = 8e-06 Identities = 30/87 (34%), Positives = 46/87 (52%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 IH DL+ +NIL+ D++V + DFG+AR+ D+ T+ G + G Sbjct: 393 IHRDLRAANILVADNLVCKIADFGLARLIEDN-----EYTARQGAKFPIKWTAPEAALYG 447 Query: 593 RISTSGDVYSFGIVLLEMLTGKRPTDP 513 R + DV+SFGI+L E++T R P Sbjct: 448 RFTIKSDVWSFGILLTELVTKGRVPYP 474
>RIPK3_MOUSE (Q9QZL0) Receptor-interacting serine/threonine-protein kinase 3 (EC| 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) (mRIP3) Length = 486 Score = 50.1 bits (118), Expect = 8e-06 Identities = 30/85 (35%), Positives = 43/85 (50%), Gaps = 2/85 (2%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARI--FLDSGPRPASSTSSIGVRXXXXXXXXXXX 603 ++H DLKPSNILLD ++ A L DFG++ SG S + G Sbjct: 139 LLHRDLKPSNILLDPELHAKLADFGLSTFQGGSQSGSGSGSGSRDSGGTLAYLDPELLFK 198 Query: 602 XXGRISTSGDVYSFGIVLLEMLTGK 528 + S + DVYSFGI++ +L G+ Sbjct: 199 VNLKASKASDVYSFGILVWAVLAGR 223
>SRC_RSVPA (P31693) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 522 Score = 50.1 bits (118), Expect = 8e-06 Identities = 30/92 (32%), Positives = 47/92 (51%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL+ +NIL+ +++V + DFG+AR+ D+ T+ G R G Sbjct: 379 VHRDLRAANILVGENLVCKVADFGLARLIEDN-----EYTARPGARFPVKWTAPEAALYG 433 Query: 593 RISTSGDVYSFGIVLLEMLTGKRPTDPMFTDG 498 R + DV+SFGI+L E+ T R P +G Sbjct: 434 RFTIKSDVWSFGILLTELTTKGRVPYPGMVNG 465
>EPHB2_COTJA (Q90344) Ephrin type-B receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor QEK5) Length = 987 Score = 49.7 bits (117), Expect = 1e-05 Identities = 30/120 (25%), Positives = 64/120 (53%), Gaps = 9/120 (7%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL N L++ ++V + DFG++R FL+ + TS++G + Sbjct: 744 VHRDLAARNTLVNSNLVCKVSDFGLSR-FLEDDTSDPTYTSALGGKIPIRWTAPEAIQYR 802 Query: 593 RISTSGDVYSFGIVLLEMLT-GKRPTDPMFTDGLDIVNFVGSEF--------PHQIHEVI 441 + +++ DV+S+GIV+ E+++ G+RP M D++N + ++ P+ +H+++ Sbjct: 803 KFTSASDVWSYGIVMWEVMSYGERPYWDMTNQ--DVINAIEQDYRLPPPMDCPNALHQLM 860
>ST32A_HUMAN (Q8WU08) Serine/threonine-protein kinase 32A (EC 2.7.11.1) (YANK1)| Length = 396 Score = 49.7 bits (117), Expect = 1e-05 Identities = 29/85 (34%), Positives = 40/85 (47%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 IIH D+KP NILLD+ H+ DF IA + PR T+ G + Sbjct: 142 IIHRDMKPDNILLDEHGHVHITDFNIAAML----PRETQITTMAGTKPYMAPEMFSSRKG 197 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRP 522 S + D +S G+ E+L G+RP Sbjct: 198 AGYSFAVDWWSLGVTAYELLRGRRP 222
>SRMS_HUMAN (Q9H3Y6) Tyrosine-protein kinase Srms (EC 2.7.10.2)| Length = 488 Score = 49.7 bits (117), Expect = 1e-05 Identities = 44/170 (25%), Positives = 68/170 (40%), Gaps = 1/170 (0%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 ++H DL N+L+DD + + DFG+AR+ D P SS+S I V+ Sbjct: 346 VVHRDLAARNVLVDDGLACKVADFGLARLLKDDIYSP-SSSSKIPVKWTAPEAANYRV-- 402 Query: 596 GRISTSGDVYSFGIVLLEMLT-GKRPTDPMFTDGLDIVNFVGSEFPHQIHEVIDIYLKGE 420 S DV+SFG++L E+ T G+ P + M HE + ++G Sbjct: 403 --FSQKSDVWSFGVLLHEVFTYGQCPYEGMTN-----------------HETLQQIMRGY 443 Query: 419 CEDSAEARSVSEGSVHQCLVSLLQVAVSCTHSIPSERANMRDAASKIQAI 270 A C + + + C S P ER + K+ AI Sbjct: 444 RLPRPAA----------CPAEVYVLMLECWRSSPEERPSFATLREKLHAI 483
>RON_HUMAN (Q04912) Macrophage-stimulating protein receptor precursor (EC| 2.7.10.1) (MSP receptor) (p185-Ron) (CDw136 antigen) [Contains: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain] Length = 1400 Score = 49.3 bits (116), Expect = 1e-05 Identities = 48/191 (25%), Positives = 72/191 (37%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL N +LD+ + DFG+AR LD S R Sbjct: 1205 VHRDLAARNCMLDESFTVKVADFGLARDILDR--EYYSVQQHRHARLPVKWMALESLQTY 1262 Query: 593 RISTSGDVYSFGIVLLEMLTGKRPTDPMFTDGLDIVNFVGSEFPHQIHEVIDIYLKGECE 414 R +T DV+SFG++L E+LT P D D+ +F+ Sbjct: 1263 RFTTKSDVWSFGVLLWELLTRGAP-PYRHIDPFDLTHFL--------------------- 1300 Query: 413 DSAEARSVSEGSVHQCLVSLLQVAVSCTHSIPSERANMRDAASKIQAIQASYLGRQT*IL 234 A+ R + + C SL QV C + P+ R R +++ I ++ LG Sbjct: 1301 --AQGRRLPQ--PEYCPDSLYQVMQQCWEADPAVRPTFRVLVGEVEQIVSALLGD----- 1351 Query: 233 QFNYVHTTTTY 201 +YV TY Sbjct: 1352 --HYVQLPATY 1360
>YRK_CHICK (Q02977) Proto-oncogene tyrosine-protein kinase Yrk (EC 2.7.10.2)| (p60-Yrk) (Yes-related kinase) Length = 535 Score = 49.3 bits (116), Expect = 1e-05 Identities = 29/87 (33%), Positives = 46/87 (52%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 IH DL+ +NIL+ D++V + DFG+AR+ D+ T+ G + G Sbjct: 385 IHRDLRAANILVGDNLVCKIADFGLARLIEDN-----EYTARQGAKFPIKWTAPEAALFG 439 Query: 593 RISTSGDVYSFGIVLLEMLTGKRPTDP 513 + + DV+SFGI+L E++T R P Sbjct: 440 KFTIKSDVWSFGILLTELVTKGRVPYP 466
>SNF1_SCHPO (O74536) SNF1-like protein kinase ssp2 (EC 2.7.11.1)| Length = 576 Score = 48.9 bits (115), Expect = 2e-05 Identities = 32/94 (34%), Positives = 41/94 (43%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 I+H DLKP N+LLDD++ + DFG++ I D S S Sbjct: 152 IVHRDLKPENLLLDDNLNVKIADFGLSNIMTDGNFLKTSCGSP------NYAAPEVINGK 205 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRPTDPMFTDGL 495 DV+S GIVL ML G+ P D F L Sbjct: 206 LYAGPEVDVWSCGIVLYVMLVGRLPFDDEFIPNL 239
>EPHA2_HUMAN (P29317) Ephrin type-A receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) Length = 976 Score = 48.9 bits (115), Expect = 2e-05 Identities = 26/85 (30%), Positives = 49/85 (57%), Gaps = 1/85 (1%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL NIL++ ++V + DFG++R+ D P ++ ++ G + Sbjct: 736 VHRDLAARNILVNSNLVCKVSDFGLSRVLEDD---PEATYTTSGGKIPIRWTAPEAISYR 792 Query: 593 RISTSGDVYSFGIVLLEMLT-GKRP 522 + +++ DV+SFGIV+ E++T G+RP Sbjct: 793 KFTSASDVWSFGIVMWEVMTYGERP 817
>PKNA2_BIFLO (Q8G4G1) Probable serine/threonine-protein kinase pknA2 (EC| 2.7.11.1) Length = 757 Score = 48.5 bits (114), Expect = 2e-05 Identities = 30/88 (34%), Positives = 45/88 (51%), Gaps = 1/88 (1%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 ++H D+KP NIL++D + DFG+A+ ++ SS G+ Sbjct: 136 VVHRDIKPENILINDRGHVQITDFGLAK------AASQATLSSTGMLLGTAAYLAPEMIE 189 Query: 596 GRISTS-GDVYSFGIVLLEMLTGKRPTD 516 +T+ GD+YS GI+ EMLTGK P D Sbjct: 190 NNQATAQGDLYSVGIMAWEMLTGKVPFD 217
>YES_XENLA (P10936) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 536 Score = 48.5 bits (114), Expect = 2e-05 Identities = 29/87 (33%), Positives = 45/87 (51%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 IH DL+ +NIL+ D++V + DFG+AR+ D+ T+ G + G Sbjct: 386 IHRDLRAANILVGDNLVCKIADFGLARLIEDN-----EYTARQGAKFPIKWTAPEAALYG 440 Query: 593 RISTSGDVYSFGIVLLEMLTGKRPTDP 513 R + DV+SFGI+L E++ R P Sbjct: 441 RFTIKSDVWSFGILLTELVAKGRVPYP 467
>SRMS_MOUSE (Q62270) Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70)| Length = 496 Score = 48.5 bits (114), Expect = 2e-05 Identities = 32/90 (35%), Positives = 46/90 (51%), Gaps = 1/90 (1%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 ++H DL N+L+ DD+ + DFG+AR+ D P SS S I V+ Sbjct: 350 VVHRDLAARNVLVGDDLTCKVADFGLARLLKDDVYSP-SSGSKIPVKWTAPEAANYRV-- 406 Query: 596 GRISTSGDVYSFGIVLLEMLT-GKRPTDPM 510 S DV+SFGI+L E+ T G+ P + M Sbjct: 407 --FSQKSDVWSFGILLYEVFTYGQCPYEGM 434
>BRAF1_HUMAN (P15056) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (p94) (v-Raf murine sarcoma viral oncogene homolog B1) Length = 766 Score = 48.1 bits (113), Expect = 3e-05 Identities = 32/86 (37%), Positives = 42/86 (48%), Gaps = 1/86 (1%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLD-SGPRPASSTSSIGVRXXXXXXXXXXXX 600 IIH DLK +NI L +D+ +GDFG+A + SG S G Sbjct: 572 IIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLS--GSILWMAPEVIRMQD 629 Query: 599 XGRISTSGDVYSFGIVLLEMLTGKRP 522 S DVY+FGIVL E++TG+ P Sbjct: 630 KNPYSFQSDVYAFGIVLYELMTGQLP 655
>SRC_RSVSE (P63185) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 48.1 bits (113), Expect = 3e-05 Identities = 29/92 (31%), Positives = 47/92 (51%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL+ +NIL+ +++V + DFG+AR+ D+ T+ G + G Sbjct: 382 VHRDLRAANILVGENLVCKVADFGLARLIEDN-----EYTARQGAKFPIKWTAPEAALYG 436 Query: 593 RISTSGDVYSFGIVLLEMLTGKRPTDPMFTDG 498 R + DV+SFGI+L E+ T R P +G Sbjct: 437 RFTIKSDVWSFGILLTELTTKGRVPYPGMGNG 468
>SRC_RSVSA (P00524) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 48.1 bits (113), Expect = 3e-05 Identities = 29/92 (31%), Positives = 47/92 (51%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL+ +NIL+ +++V + DFG+AR+ D+ T+ G + G Sbjct: 382 VHRDLRAANILVGENLVCKVADFGLARLIEDN-----EYTARQGAKFPIKWTAPEAALYG 436 Query: 593 RISTSGDVYSFGIVLLEMLTGKRPTDPMFTDG 498 R + DV+SFGI+L E+ T R P +G Sbjct: 437 RFTIKSDVWSFGILLTELTTKGRVPYPGMGNG 468
>SRC_AVISR (P00525) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 48.1 bits (113), Expect = 3e-05 Identities = 29/92 (31%), Positives = 47/92 (51%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL+ +NIL+ +++V + DFG+AR+ D+ T+ G + G Sbjct: 382 VHRDLRAANILVGENLVCKVADFGLARLIEDN-----EYTARQGAKFPIKWTAPEAALYG 436 Query: 593 RISTSGDVYSFGIVLLEMLTGKRPTDPMFTDG 498 R + DV+SFGI+L E+ T R P +G Sbjct: 437 RFTIKSDVWSFGILLTELTTKGRVPYPGMGNG 468
>RMIL_AVEVR (P27966) Serine/threonine-protein kinase transforming protein Rmil| (EC 2.7.11.1) Length = 450 Score = 48.1 bits (113), Expect = 3e-05 Identities = 32/86 (37%), Positives = 42/86 (48%), Gaps = 1/86 (1%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLD-SGPRPASSTSSIGVRXXXXXXXXXXXX 600 IIH DLK +NI L +D+ +GDFG+A + SG S G Sbjct: 198 IIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLS--GSILWMAPEVIRMQD 255 Query: 599 XGRISTSGDVYSFGIVLLEMLTGKRP 522 S DVY+FGIVL E++TG+ P Sbjct: 256 KNPYSFQSDVYAFGIVLYELMTGQLP 281
>EPHA3_MOUSE (P29319) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ETK1) (MEK4) Length = 983 Score = 48.1 bits (113), Expect = 3e-05 Identities = 28/104 (26%), Positives = 55/104 (52%), Gaps = 1/104 (0%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL NIL++ ++V + DFG++R+ D P ++ ++ G + Sbjct: 743 VHRDLAARNILINSNLVCKVSDFGLSRVLEDD---PEAAYTTRGGKIPIRWTSPEAMSYR 799 Query: 593 RISTSGDVYSFGIVLLEMLT-GKRPTDPMFTDGLDIVNFVGSEF 465 + +++ DV+S+GIVL E+++ G+RP M D++ V + Sbjct: 800 KFTSASDVWSYGIVLWEVMSYGERPYSQM--SNQDVIKAVDERY 841
>ARAF_PIG (O19004) A-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (A-Raf-1) Length = 606 Score = 48.1 bits (113), Expect = 3e-05 Identities = 30/86 (34%), Positives = 42/86 (48%), Gaps = 1/86 (1%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLD-SGPRPASSTSSIGVRXXXXXXXXXXXX 600 IIH DLK +NI L + + +GDFG+A + SG +P S G Sbjct: 425 IIHRDLKSNNIFLHEGLTVKIGDFGLATVKTRWSGAQPLEQPS--GSVLWMAAEVIRMQD 482 Query: 599 XGRISTSGDVYSFGIVLLEMLTGKRP 522 S DVY++G+VL E++TG P Sbjct: 483 PNPYSFQSDVYAYGVVLYELMTGSLP 508
>ARAF_HUMAN (P10398) A-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (A-raf-1) (Proto-oncogene Pks) Length = 606 Score = 48.1 bits (113), Expect = 3e-05 Identities = 30/86 (34%), Positives = 42/86 (48%), Gaps = 1/86 (1%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLD-SGPRPASSTSSIGVRXXXXXXXXXXXX 600 IIH DLK +NI L + + +GDFG+A + SG +P S G Sbjct: 425 IIHRDLKSNNIFLHEGLTVKIGDFGLATVKTRWSGAQPLEQPS--GSVLWMAAEVIRMQD 482 Query: 599 XGRISTSGDVYSFGIVLLEMLTGKRP 522 S DVY++G+VL E++TG P Sbjct: 483 PNPYSFQSDVYAYGVVLYELMTGSLP 508
>RMIL_AVII1 (P10533) Serine/threonine-protein kinase transforming protein Rmil| (EC 2.7.11.1) Length = 367 Score = 48.1 bits (113), Expect = 3e-05 Identities = 32/86 (37%), Positives = 42/86 (48%), Gaps = 1/86 (1%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLD-SGPRPASSTSSIGVRXXXXXXXXXXXX 600 IIH DLK +NI L +D+ +GDFG+A + SG S G Sbjct: 182 IIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLS--GSILWMAPEVIRMQD 239 Query: 599 XGRISTSGDVYSFGIVLLEMLTGKRP 522 S DVY+FGIVL E++TG+ P Sbjct: 240 KNPYSFQSDVYAFGIVLYELMTGQLP 265
>FGR_MOUSE (P14234) Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2)| (P55-FGR) (C-FGR) Length = 517 Score = 48.1 bits (113), Expect = 3e-05 Identities = 28/87 (32%), Positives = 44/87 (50%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 IH DL+ +NIL+ + ++ + DFG+AR+ D+ P G + G Sbjct: 367 IHRDLRAANILVGEYLICKIADFGLARLIEDNEYNPQQ-----GTKFPIKWTAPEAALFG 421 Query: 593 RISTSGDVYSFGIVLLEMLTGKRPTDP 513 R + DV+SFGI+L E++T R P Sbjct: 422 RFTVKSDVWSFGILLTELITKGRVPYP 448
>ARAF_RAT (P14056) A-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) Length = 604 Score = 48.1 bits (113), Expect = 3e-05 Identities = 30/86 (34%), Positives = 42/86 (48%), Gaps = 1/86 (1%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLD-SGPRPASSTSSIGVRXXXXXXXXXXXX 600 IIH DLK +NI L + + +GDFG+A + SG +P S G Sbjct: 423 IIHRDLKSNNIFLHEGLTVKIGDFGLATVKTRWSGAQPLEQPS--GSVLWMAAEVIRMQD 480 Query: 599 XGRISTSGDVYSFGIVLLEMLTGKRP 522 S DVY++G+VL E++TG P Sbjct: 481 PNPYSFQSDVYAYGVVLYELMTGSLP 506
>ARAF_MOUSE (P04627) A-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) Length = 604 Score = 48.1 bits (113), Expect = 3e-05 Identities = 30/86 (34%), Positives = 42/86 (48%), Gaps = 1/86 (1%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLD-SGPRPASSTSSIGVRXXXXXXXXXXXX 600 IIH DLK +NI L + + +GDFG+A + SG +P S G Sbjct: 423 IIHRDLKSNNIFLHEGLTVKIGDFGLATVKTRWSGAQPLEQPS--GSVLWMAAEVIRMQD 480 Query: 599 XGRISTSGDVYSFGIVLLEMLTGKRP 522 S DVY++G+VL E++TG P Sbjct: 481 PNPYSFQSDVYAYGVVLYELMTGSLP 506
>BRAF1_MOUSE (P28028) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Fragment) Length = 328 Score = 48.1 bits (113), Expect = 3e-05 Identities = 32/86 (37%), Positives = 42/86 (48%), Gaps = 1/86 (1%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLD-SGPRPASSTSSIGVRXXXXXXXXXXXX 600 IIH DLK +NI L +D+ +GDFG+A + SG S G Sbjct: 134 IIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLS--GSILWMAPEVIRMQD 191 Query: 599 XGRISTSGDVYSFGIVLLEMLTGKRP 522 S DVY+FGIVL E++TG+ P Sbjct: 192 KNPYSFQSDVYAFGIVLYELMTGQLP 217
>BRAF1_COTJA (P34908) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (RMIL serine/threonine-protein kinase) (c-RMIL) Length = 807 Score = 48.1 bits (113), Expect = 3e-05 Identities = 32/86 (37%), Positives = 42/86 (48%), Gaps = 1/86 (1%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLD-SGPRPASSTSSIGVRXXXXXXXXXXXX 600 IIH DLK +NI L +D+ +GDFG+A + SG S G Sbjct: 612 IIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLS--GSILWMAPEVIRMQD 669 Query: 599 XGRISTSGDVYSFGIVLLEMLTGKRP 522 S DVY+FGIVL E++TG+ P Sbjct: 670 KNPYSFQSDVYAFGIVLYELMTGQLP 695
>BRAF1_CHICK (Q04982) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Rmil serine/threonine-protein kinase) (c-Rmil) Length = 806 Score = 48.1 bits (113), Expect = 3e-05 Identities = 32/86 (37%), Positives = 42/86 (48%), Gaps = 1/86 (1%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLD-SGPRPASSTSSIGVRXXXXXXXXXXXX 600 IIH DLK +NI L +D+ +GDFG+A + SG S G Sbjct: 612 IIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLS--GSILWMAPEVIRMQD 669 Query: 599 XGRISTSGDVYSFGIVLLEMLTGKRP 522 S DVY+FGIVL E++TG+ P Sbjct: 670 KNPYSFQSDVYAFGIVLYELMTGQLP 695
>EPHA2_MOUSE (Q03145) Ephrin type-A receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2) Length = 977 Score = 47.8 bits (112), Expect = 4e-05 Identities = 25/85 (29%), Positives = 49/85 (57%), Gaps = 1/85 (1%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL NIL++ ++V + DFG++R+ D P ++ ++ G + Sbjct: 737 VHRDLAARNILVNSNLVCKVSDFGLSRVLEDD---PEATYTTSGGKIPIRWTAPEAISYR 793 Query: 593 RISTSGDVYSFGIVLLEMLT-GKRP 522 + +++ DV+S+GIV+ E++T G+RP Sbjct: 794 KFTSASDVWSYGIVMWEVMTYGERP 818
>M3K4_HUMAN (Q9Y6R4) Mitogen-activated protein kinase kinase kinase 4 (EC| 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4) (MAP three kinase 1) Length = 1607 Score = 47.8 bits (112), Expect = 4e-05 Identities = 26/86 (30%), Positives = 43/86 (50%), Gaps = 1/86 (1%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIA-RIFLDSGPRPASSTSSIGVRXXXXXXXXXXXX 600 I+H D+K +NI L + LGDFG + ++ ++ P S++G Sbjct: 1458 IVHRDIKGANIFLTSSGLIKLGDFGCSVKLKNNAQTMPGEVNSTLGTAAYMAPEVITRAK 1517 Query: 599 XGRISTSGDVYSFGIVLLEMLTGKRP 522 + D++S G V++EM+TGKRP Sbjct: 1518 GEGHGRAADIWSLGCVVIEMVTGKRP 1543
>MEK2_CAEEL (Q10664) Dual specificity mitogen-activated protein kinase kinase| mek-2 (EC 2.7.12.2) (MAP kinase kinase mek-2) Length = 387 Score = 47.8 bits (112), Expect = 4e-05 Identities = 44/185 (23%), Positives = 76/185 (41%), Gaps = 19/185 (10%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 I+H D+KPSN+L++ + L DFG++ + +DS + S +G R Sbjct: 191 ILHRDVKPSNMLVNSNGEIKLCDFGVSGMLIDS-----MANSFVGTR---SYMAPERLTG 242 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRPTD--------PMF---------TDGLDIVNFVGSE 468 + S D++SFG+ L+E+L G+ P MF D L+ N+ Sbjct: 243 SHYTISSDIWSFGLSLVELLIGRYPVPAPSQAEYATMFNVAENEIELADSLEEPNYHPPS 302 Query: 467 FPHQ--IHEVIDIYLKGECEDSAEARSVSEGSVHQCLVSLLQVAVSCTHSIPSERANMRD 294 P I E++D + G + E ++ C +PSERA ++ Sbjct: 303 NPASMAIFEMLDYIVNGPPPTLPKRFFTDE---------VIGFVSKCLRKLPSERATLKS 353 Query: 293 AASKI 279 + + Sbjct: 354 LTADV 358
>ST32A_MOUSE (Q8BGW6) Serine/threonine-protein kinase 32A (EC 2.7.11.1)| Length = 398 Score = 47.8 bits (112), Expect = 4e-05 Identities = 28/85 (32%), Positives = 40/85 (47%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 IIH D+KP NILLD+ H+ DF IA + P+ T+ G + Sbjct: 142 IIHRDMKPDNILLDEHGHVHITDFNIAAML----PKETRITTVAGTKPYMAPEMFTSRKE 197 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRP 522 S + D +S G+ E+L G+RP Sbjct: 198 TGYSFAVDWWSLGVTAYELLRGRRP 222
>SRC_RSVH1 (P25020) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 47.8 bits (112), Expect = 4e-05 Identities = 34/122 (27%), Positives = 54/122 (44%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL+ +NIL+ +++V + DFG+AR+ D+ T+ G + G Sbjct: 382 VHRDLRAANILVGENLVCKVADFGLARLIEDN-----EYTARQGAKFPIKWTAPEAALYG 436 Query: 593 RISTSGDVYSFGIVLLEMLTGKRPTDPMFTDGLDIVNFVGSEFPHQIHEVIDIYLKGECE 414 R + DV+SFGI+L E+ T R P V E Q+ + EC Sbjct: 437 RFTIKSDVWSFGILLTELTTKGRVPYP---------GMVNREVLDQVERAYRMPCPPECP 487 Query: 413 DS 408 +S Sbjct: 488 ES 489
>SNF1_CANTR (O94168) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 619 Score = 47.8 bits (112), Expect = 4e-05 Identities = 30/94 (31%), Positives = 40/94 (42%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 I+H DLKP N+LLDD + + DFG++ I D S S Sbjct: 170 IVHRDLKPENLLLDDQLNVKIADFGLSNIMTDGNFLKTSCGSP------NYAAPEVISGK 223 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRPTDPMFTDGL 495 DV+S G++L ML G+ P D F L Sbjct: 224 LYAGPEVDVWSSGVILYVMLCGRLPFDDEFIPAL 257
>M3K4_MOUSE (O08648) Mitogen-activated protein kinase kinase kinase 4 (EC| 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4) Length = 1597 Score = 47.8 bits (112), Expect = 4e-05 Identities = 26/86 (30%), Positives = 43/86 (50%), Gaps = 1/86 (1%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIA-RIFLDSGPRPASSTSSIGVRXXXXXXXXXXXX 600 I+H D+K +NI L + LGDFG + ++ ++ P S++G Sbjct: 1448 IVHRDIKGANIFLTSSGLIKLGDFGCSVKLKNNAQTMPGEVNSTLGTAAYMAPEVITRAK 1507 Query: 599 XGRISTSGDVYSFGIVLLEMLTGKRP 522 + D++S G V++EM+TGKRP Sbjct: 1508 GEGHGRAADIWSLGCVVIEMVTGKRP 1533
>PKNL_MYCTU (O53510) Probable serine/threonine-protein kinase pknL (EC| 2.7.11.1) Length = 399 Score = 47.8 bits (112), Expect = 4e-05 Identities = 29/85 (34%), Positives = 40/85 (47%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 ++H D+KP NIL+ DD L DFG+ R AS TS+ + Sbjct: 138 LVHRDVKPENILISDDGDVKLADFGLVR-----AVAAASITSTGVILGTAAYLSPEQVRD 192 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRP 522 G DVYS G+++ E+LTG P Sbjct: 193 GNADPRSDVYSVGVLVYELLTGHTP 217
>PKNL_MYCBO (Q7TYY6) Probable serine/threonine-protein kinase pknL (EC| 2.7.11.1) Length = 399 Score = 47.8 bits (112), Expect = 4e-05 Identities = 29/85 (34%), Positives = 40/85 (47%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 ++H D+KP NIL+ DD L DFG+ R AS TS+ + Sbjct: 138 LVHRDVKPENILISDDGDVKLADFGLVR-----AVAAASITSTGVILGTAAYLSPEQVRD 192 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRP 522 G DVYS G+++ E+LTG P Sbjct: 193 GNADPRSDVYSVGVLVYELLTGHTP 217
>KOK0_YEAST (Q12236) Probable serine/threonine-protein kinase YOL100W (EC| 2.7.11.1) Length = 1081 Score = 47.8 bits (112), Expect = 4e-05 Identities = 27/90 (30%), Positives = 42/90 (46%), Gaps = 5/90 (5%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 IIH D+KP NILLD +M L DFG A++ + + + R Sbjct: 299 IIHRDIKPENILLDGEMKIKLTDFGTAKLLNPTNNSVSKPEYDLSTRSKSFVGTAEYVSP 358 Query: 596 GRISTS-----GDVYSFGIVLLEMLTGKRP 522 ++ S D+++FG +L +M+ GK P Sbjct: 359 ELLNDSFTDYRCDIWAFGCILFQMIAGKPP 388
>GCN2_YEAST (P15442) Serine/threonine-protein kinase GCN2 (EC 2.7.11.1)| Length = 1590 Score = 47.8 bits (112), Expect = 4e-05 Identities = 41/122 (33%), Positives = 55/122 (45%), Gaps = 17/122 (13%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIAR--------IFLDSGPRPASS---TSSIGVRXX 630 IIH DLKP NI +D+ +GDFG+A+ + LDS P SS TS+IG Sbjct: 762 IIHRDLKPMNIFIDESRNVKIGDFGLAKNVHRSLDILKLDSQNLPGSSDNLTSAIG--TA 819 Query: 629 XXXXXXXXXXXGRISTSGDVYSFGIVLLEMLTGKRPTDPMFTDGLDIVNF------VGSE 468 G + D+YS GI+ EM+ F+ G++ VN V E Sbjct: 820 MYVATEVLDGTGHYNEKIDMYSLGIIFFEMIY-------PFSTGMERVNILKKLRSVSIE 872 Query: 467 FP 462 FP Sbjct: 873 FP 874
>EPHA6_RAT (P54758) Ephrin type-A receptor 6 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2) Length = 1035 Score = 47.8 bits (112), Expect = 4e-05 Identities = 25/85 (29%), Positives = 49/85 (57%), Gaps = 1/85 (1%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL NIL++ ++V + DFG++R+ D P ++ ++ G + Sbjct: 794 VHRDLAARNILVNSNLVCKVSDFGLSRVLEDD---PEAAYTTTGGKIPIRWTAPEAIAYR 850 Query: 593 RISTSGDVYSFGIVLLEMLT-GKRP 522 + S++ DV+S+GIV+ E+++ G+RP Sbjct: 851 KFSSASDVWSYGIVMWEVMSYGERP 875
>EPHA3_RAT (O08680) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor REK4) (TYRO-4) Length = 984 Score = 47.4 bits (111), Expect = 5e-05 Identities = 25/85 (29%), Positives = 49/85 (57%), Gaps = 1/85 (1%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL NIL++ ++V + DFG++R+ D P ++ ++ G + Sbjct: 744 VHRDLAARNILINSNLVCKVSDFGLSRVLEDD---PEAAYTTRGGKIPVRWTSPEATAYR 800 Query: 593 RISTSGDVYSFGIVLLEMLT-GKRP 522 + +++ DV+S+GIVL E+++ G+RP Sbjct: 801 KFTSASDVWSYGIVLWEVMSYGERP 825
>SRC_AVIST (P14085) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 556 Score = 47.4 bits (111), Expect = 5e-05 Identities = 28/87 (32%), Positives = 45/87 (51%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL+ +NIL+ +++V + DFG+AR+ D+ T+ G + G Sbjct: 382 VHRDLRAANILVGENLVCKVADFGLARLIEDN-----EYTARQGAKFPIKWTAPEAALYG 436 Query: 593 RISTSGDVYSFGIVLLEMLTGKRPTDP 513 R + DV+SFGI+L E+ T R P Sbjct: 437 RFTIKSDVWSFGILLTELTTKGRVPYP 463
>SRC_MOUSE (P05480) Neuronal proto-oncogene tyrosine-protein kinase Src (EC| 2.7.10.2) (p60-Src) (c-Src) (pp60c-src) Length = 540 Score = 47.4 bits (111), Expect = 5e-05 Identities = 28/87 (32%), Positives = 45/87 (51%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL+ +NIL+ +++V + DFG+AR+ D+ T+ G + G Sbjct: 390 VHRDLRAANILVGENLVCKVADFGLARLIEDN-----EYTARQGAKFPIKWTAPEAALYG 444 Query: 593 RISTSGDVYSFGIVLLEMLTGKRPTDP 513 R + DV+SFGI+L E+ T R P Sbjct: 445 RFTIKSDVWSFGILLTELTTKGRVPYP 471
>SRC_RSVP (P00526) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 47.4 bits (111), Expect = 5e-05 Identities = 28/87 (32%), Positives = 45/87 (51%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL+ +NIL+ +++V + DFG+AR+ D+ T+ G + G Sbjct: 382 VHRDLRAANILVGENLVCKVADFGLARLIEDN-----EYTARQGAKFPIKWTAPEAALYG 436 Query: 593 RISTSGDVYSFGIVLLEMLTGKRPTDP 513 R + DV+SFGI+L E+ T R P Sbjct: 437 RFTIKSDVWSFGILLTELTTKGRVPYP 463
>SRC_AVIS2 (P15054) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 586 Score = 47.4 bits (111), Expect = 5e-05 Identities = 28/87 (32%), Positives = 45/87 (51%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL+ +NIL+ +++V + DFG+AR+ D+ T+ G + G Sbjct: 382 VHRDLRAANILVGENLVCKVADFGLARLIEDN-----EYTARQGAKFPIKWTAPEAALYG 436 Query: 593 RISTSGDVYSFGIVLLEMLTGKRPTDP 513 R + DV+SFGI+L E+ T R P Sbjct: 437 RFTIKSDVWSFGILLTELTTKGRVPYP 463
>SRC2_XENLA (P13116) Tyrosine-protein kinase Src-2 (EC 2.7.10.2) (p60-Src-2)| Length = 531 Score = 47.4 bits (111), Expect = 5e-05 Identities = 28/87 (32%), Positives = 45/87 (51%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL+ +NIL+ +++V + DFG+AR+ D+ T+ G + G Sbjct: 381 VHRDLRAANILVGENLVCKVADFGLARLIEDN-----EYTARQGAKFPIKWTAPEAALYG 435 Query: 593 RISTSGDVYSFGIVLLEMLTGKRPTDP 513 R + DV+SFGI+L E+ T R P Sbjct: 436 RFTIKSDVWSFGILLTELTTKGRVPYP 462
>SRC1_XENLA (P13115) Tyrosine-protein kinase Src-1 (EC 2.7.10.2) (p60-Src-1)| Length = 531 Score = 47.4 bits (111), Expect = 5e-05 Identities = 28/87 (32%), Positives = 45/87 (51%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL+ +NIL+ +++V + DFG+AR+ D+ T+ G + G Sbjct: 381 VHRDLRAANILVGENLVCKVADFGLARLIEDN-----EYTARQGAKFPIKWTAPEAALYG 435 Query: 593 RISTSGDVYSFGIVLLEMLTGKRPTDP 513 R + DV+SFGI+L E+ T R P Sbjct: 436 RFTIKSDVWSFGILLTELTTKGRVPYP 462
>SNF1_CANAL (P52497) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 620 Score = 47.4 bits (111), Expect = 5e-05 Identities = 31/94 (32%), Positives = 43/94 (45%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 I+H DLKP N+LLDD + + DFG++ I D G +S S Sbjct: 171 IVHRDLKPENLLLDDQLNVKIADFGLSNIMTD-GNFLKTSCGSPNYMPAPEVISGKLYAG 229 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRPTDPMFTDGL 495 + DV+S G++L ML G+ P D F L Sbjct: 230 PEV----DVWSAGVILYVMLCGRLPFDDEFIPAL 259
>FYN_XENLA (P13406) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 536 Score = 47.4 bits (111), Expect = 5e-05 Identities = 28/87 (32%), Positives = 45/87 (51%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 IH DL+ +NIL+ + ++ + DFG+AR+ D+ T+ G + G Sbjct: 386 IHRDLRSANILVGNGLICKIADFGLARLIEDN-----EYTARQGAKFPIKWTAPEAALYG 440 Query: 593 RISTSGDVYSFGIVLLEMLTGKRPTDP 513 R + DV+SFGI+L E++T R P Sbjct: 441 RFTIKSDVWSFGILLTELVTKGRVPYP 467
>FYN_HUMAN (P06241) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) (Protooncogene Syn) (SLK) Length = 536 Score = 47.4 bits (111), Expect = 5e-05 Identities = 28/87 (32%), Positives = 45/87 (51%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 IH DL+ +NIL+ + ++ + DFG+AR+ D+ T+ G + G Sbjct: 386 IHRDLRSANILVGNGLICKIADFGLARLIEDN-----EYTARQGAKFPIKWTAPEAALYG 440 Query: 593 RISTSGDVYSFGIVLLEMLTGKRPTDP 513 R + DV+SFGI+L E++T R P Sbjct: 441 RFTIKSDVWSFGILLTELVTKGRVPYP 467
>PKNB_LACLA (Q9CEF5) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 627 Score = 47.4 bits (111), Expect = 5e-05 Identities = 27/87 (31%), Positives = 41/87 (47%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 IIH DLKP N+L+ + DFGIA+ ++ S T + + Sbjct: 132 IIHRDLKPQNVLVSSSGTVKVTDFGIAKALSET-----SLTQTNTMFGSVHYLSPEQARG 186 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRPTD 516 + D+Y+ GI+L E+LTG+ P D Sbjct: 187 SNATVQSDIYAIGIILFELLTGQIPFD 213
>SRC_CHICK (P00523) Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2)| (p60-Src) (c-Src) (pp60c-src) Length = 532 Score = 47.4 bits (111), Expect = 5e-05 Identities = 28/87 (32%), Positives = 45/87 (51%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL+ +NIL+ +++V + DFG+AR+ D+ T+ G + G Sbjct: 382 VHRDLRAANILVGENLVCKVADFGLARLIEDN-----EYTARQGAKFPIKWTAPEAALYG 436 Query: 593 RISTSGDVYSFGIVLLEMLTGKRPTDP 513 R + DV+SFGI+L E+ T R P Sbjct: 437 RFTIKSDVWSFGILLTELTTKGRVPYP 463
>FYN_MOUSE (P39688) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 533 Score = 47.4 bits (111), Expect = 5e-05 Identities = 28/87 (32%), Positives = 45/87 (51%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 IH DL+ +NIL+ + ++ + DFG+AR+ D+ T+ G + G Sbjct: 383 IHRDLRSANILVGNGLICKIADFGLARLIEDN-----EYTARQGAKFPIKWTAPEAALYG 437 Query: 593 RISTSGDVYSFGIVLLEMLTGKRPTDP 513 R + DV+SFGI+L E++T R P Sbjct: 438 RFTIKSDVWSFGILLTELVTKGRVPYP 464
>FYN_CHICK (Q05876) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 533 Score = 47.4 bits (111), Expect = 5e-05 Identities = 28/87 (32%), Positives = 45/87 (51%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 IH DL+ +NIL+ + ++ + DFG+AR+ D+ T+ G + G Sbjct: 383 IHRDLRSANILVGNGLICKIADFGLARLIEDN-----EYTARQGAKFPIKWTAPEAALYG 437 Query: 593 RISTSGDVYSFGIVLLEMLTGKRPTDP 513 R + DV+SFGI+L E++T R P Sbjct: 438 RFTIKSDVWSFGILLTELVTKGRVPYP 464
>SRC_AVISS (P14084) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 567 Score = 47.4 bits (111), Expect = 5e-05 Identities = 28/87 (32%), Positives = 45/87 (51%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL+ +NIL+ +++V + DFG+AR+ D+ T+ G + G Sbjct: 382 VHRDLRAANILVGENLVCKVADFGLARLIEDN-----EYTARQGAKFPIKWTAPEAALYG 436 Query: 593 RISTSGDVYSFGIVLLEMLTGKRPTDP 513 R + DV+SFGI+L E+ T R P Sbjct: 437 RFTIKSDVWSFGILLTELTTKGRVPYP 463
>SRC_RAT (Q9WUD9) Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2)| (p60-Src) (c-Src) (pp60c-src) Length = 535 Score = 47.4 bits (111), Expect = 5e-05 Identities = 28/87 (32%), Positives = 45/87 (51%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL+ +NIL+ +++V + DFG+AR+ D+ T+ G + G Sbjct: 385 VHRDLRAANILVGENLVCKVADFGLARLIEDN-----EYTARQGAKFPIKWTAPEAALYG 439 Query: 593 RISTSGDVYSFGIVLLEMLTGKRPTDP 513 R + DV+SFGI+L E+ T R P Sbjct: 440 RFTIKSDVWSFGILLTELTTKGRVPYP 466
>SRC_HUMAN (P12931) Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2)| (p60-Src) (c-Src) (pp60c-src) Length = 535 Score = 47.4 bits (111), Expect = 5e-05 Identities = 28/87 (32%), Positives = 45/87 (51%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL+ +NIL+ +++V + DFG+AR+ D+ T+ G + G Sbjct: 385 VHRDLRAANILVGENLVCKVADFGLARLIEDN-----EYTARQGAKFPIKWTAPEAALYG 439 Query: 593 RISTSGDVYSFGIVLLEMLTGKRPTDP 513 R + DV+SFGI+L E+ T R P Sbjct: 440 RFTIKSDVWSFGILLTELTTKGRVPYP 466
>EPHA8_RAT (P29321) Ephrin type-A receptor 8 (EC 2.7.10.1) (Tyrosine-protein| kinase receptor EEK) (EPH- and ELK-related kinase) (Fragment) Length = 372 Score = 47.0 bits (110), Expect = 7e-05 Identities = 28/85 (32%), Positives = 45/85 (52%), Gaps = 1/85 (1%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 IH DL NIL+D +V + DFG++R D P ++ ++ G + Sbjct: 124 IHRDLAARNILVDGRLVCKVSDFGLSRALEDD---PEAAYTTAGGKIPIRWTAPEAIAFR 180 Query: 593 RISTSGDVYSFGIVLLEMLT-GKRP 522 S++ DV+SFG+V+ E+L G+RP Sbjct: 181 TFSSASDVWSFGVVMWEVLAYGERP 205
>PHO85_YEAST (P17157) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 305 Score = 47.0 bits (110), Expect = 7e-05 Identities = 32/83 (38%), Positives = 43/83 (51%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 I+H DLKP N+L++ LGDFG+AR F P ++ SS V Sbjct: 129 ILHRDLKPQNLLINKRGQLKLGDFGLARAF----GIPVNTFSS-EVVTLWYRAPDVLMGS 183 Query: 596 GRISTSGDVYSFGIVLLEMLTGK 528 STS D++S G +L EM+TGK Sbjct: 184 RTYSTSIDIWSCGCILAEMITGK 206
>FGR_FSVGR (P00544) Tyrosine-protein kinase transforming protein Fgr (EC| 2.7.10.2) Length = 545 Score = 47.0 bits (110), Expect = 7e-05 Identities = 28/87 (32%), Positives = 44/87 (50%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 IH DL+ +NIL+ + +V + DFG+AR+ D+ P G + G Sbjct: 402 IHRDLRAANILVGERLVCKIADFGLARLIEDNEYNPRQ-----GAKFPIKWTAPEAALFG 456 Query: 593 RISTSGDVYSFGIVLLEMLTGKRPTDP 513 R + DV+SFGI+L E+++ R P Sbjct: 457 RFTIKSDVWSFGILLTELISKGRVPYP 483
>EPHA3_HUMAN (P29320) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ETK1) (HEK) (HEK4) Length = 983 Score = 47.0 bits (110), Expect = 7e-05 Identities = 25/85 (29%), Positives = 49/85 (57%), Gaps = 1/85 (1%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL NIL++ ++V + DFG++R+ D P ++ ++ G + Sbjct: 743 VHRDLAARNILINSNLVCKVSDFGLSRVLEDD---PEAAYTTRGGKIPIRWTSPEAIAYR 799 Query: 593 RISTSGDVYSFGIVLLEMLT-GKRP 522 + +++ DV+S+GIVL E+++ G+RP Sbjct: 800 KFTSASDVWSYGIVLWEVMSYGERP 824
>BCK1_YEAST (Q01389) Serine/threonine-protein kinase BCK1/SLK1/SSP31 (EC| 2.7.11.1) Length = 1478 Score = 47.0 bits (110), Expect = 7e-05 Identities = 29/86 (33%), Positives = 42/86 (48%), Gaps = 1/86 (1%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 I+H D+K N+LLD D + + DFGI+R D S S + +R Sbjct: 1299 ILHRDMKADNLLLDQDGICKISDFGISRKSKD-----IYSNSDMTMRGTVFWMAPEMVDT 1353 Query: 596 GR-ISTSGDVYSFGIVLLEMLTGKRP 522 + S D++S G ++LEM GKRP Sbjct: 1354 KQGYSAKVDIWSLGCIVLEMFAGKRP 1379
>MK15_HUMAN (Q8TD08) Mitogen-activated protein kinase 15 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 8) Length = 544 Score = 47.0 bits (110), Expect = 7e-05 Identities = 32/90 (35%), Positives = 43/90 (47%), Gaps = 2/90 (2%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIF--LDSGPRPASSTSSIGVRXXXXXXXXXXX 603 ++H D KPSN+LLD + L DFG+AR L GP + T + R Sbjct: 133 VVHRDQKPSNVLLDANCTVKLCDFGLARSLGDLPEGPEDQAVTEYVATR--WYRAPEVLL 190 Query: 602 XXGRISTSGDVYSFGIVLLEMLTGKRPTDP 513 R + D++S G +L EML G RP P Sbjct: 191 SSHRYTLGVDMWSLGCILGEMLRG-RPLFP 219
>KS6A2_HUMAN (Q15349) Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1)| (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (MAP kinase-activated protein kinase 1c) (MAPKAPK1C) Length = 733 Score = 47.0 bits (110), Expect = 7e-05 Identities = 29/85 (34%), Positives = 43/85 (50%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 II+ DLKP NILLD++ + DFG+++ +D R S +I Sbjct: 180 IIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNRRGH--- 236 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRP 522 + S D +SFG+++ EMLTG P Sbjct: 237 ---TQSADWWSFGVLMFEMLTGSLP 258
>YPC2_CAEEL (Q11179) Putative serine/threonine-protein kinase C05D10.2 in| chromosome III (EC 2.7.11.24) Length = 470 Score = 47.0 bits (110), Expect = 7e-05 Identities = 40/139 (28%), Positives = 55/139 (39%), Gaps = 5/139 (3%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIF-----LDSGPRPASSTSSIGVRXXXXXXXX 612 ++H DLKPSN+LLD D L DFG+AR G + T + R Sbjct: 133 VLHRDLKPSNVLLDADCRVKLADFGLARSLSSLEDYPEGQKMPDLTEYVATR--WYRSPE 190 Query: 611 XXXXXGRISTSGDVYSFGIVLLEMLTGKRPTDPMFTDGLDIVNFVGSEFPHQIHEVIDIY 432 R + D++S G +L EML G+ F GS +QI +++ Sbjct: 191 ILLAAKRYTKGVDMWSLGCILAEMLIGR-------------ALFPGSSTINQIERIMNTI 237 Query: 431 LKGECEDSAEARSVSEGSV 375 K D A S SV Sbjct: 238 AKPSRADIASIGSHYAASV 256
>PKNX_STRCO (Q9XA16) Probable serine/threonine-protein kinase SCO3848 (EC| 2.7.11.1) Length = 673 Score = 46.6 bits (109), Expect = 9e-05 Identities = 27/85 (31%), Positives = 42/85 (49%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 I+H D+KP+N++L + + DFGIAR DSG + + IG Sbjct: 134 IVHRDIKPANVMLTRNGQVKVMDFGIARAMGDSGMTMTQTAAVIG---TAQYLSPEQAKG 190 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRP 522 ++ D+YS G +L E+LT + P Sbjct: 191 EQVDARSDLYSTGCLLYELLTVRPP 215
>KPK1_ARATH (P42818) Serine/threonine-protein kinase AtPK1/AtPK6 (EC 2.7.11.1)| Length = 465 Score = 46.6 bits (109), Expect = 9e-05 Identities = 32/85 (37%), Positives = 42/85 (49%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 I+H DLKP NIL+D D L DFG+A+ F ++ S S G Sbjct: 253 IMHRDLKPENILMDTDGHVMLTDFGLAKEFEEN----TRSNSMCGTTEYMAPEIVRGKGH 308 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRP 522 + + D +S GI+L EMLTGK P Sbjct: 309 DK---AADWWSVGILLYEMLTGKPP 330
>EPHA8_MOUSE (O09127) Ephrin type-A receptor 8 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase) Length = 1004 Score = 46.6 bits (109), Expect = 9e-05 Identities = 27/85 (31%), Positives = 45/85 (52%), Gaps = 1/85 (1%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 IH DL N+L+D +V + DFG++R D P ++ ++ G + Sbjct: 756 IHRDLAARNVLVDGRLVCKVSDFGLSRALEDD---PEAAYTTAGGKIPIRWTAPEAIAFR 812 Query: 593 RISTSGDVYSFGIVLLEMLT-GKRP 522 S++ DV+SFG+V+ E+L G+RP Sbjct: 813 TFSSASDVWSFGVVMWEVLAYGERP 837
>HEP_DROME (Q23977) Dual specificity mitogen-activated protein kinase kinase| hemipterous (EC 2.7.12.2) (MAPKK) Length = 1178 Score = 46.6 bits (109), Expect = 9e-05 Identities = 34/105 (32%), Positives = 50/105 (47%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 +IH D+KPSNIL+D+ L DFGI+ +DS ++T S G Sbjct: 316 VIHRDVKPSNILIDERGNIKLCDFGISGRLVDS----KANTRSAGC-AAYMAPERIDPKK 370 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRPTDPMFTDGLDIVNFVGSEFP 462 + DV+S GI L+E+ T + P + TD + + SE P Sbjct: 371 PKYDIRADVWSLGITLVELATARSPYEGCNTDFEVLTKVLDSEPP 415
>YES_HUMAN (P07947) Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2)| (p61-Yes) (c-Yes) Length = 542 Score = 46.6 bits (109), Expect = 9e-05 Identities = 28/87 (32%), Positives = 45/87 (51%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 IH DL+ +NIL+ +++V + DFG+AR+ D+ T+ G + G Sbjct: 392 IHRDLRAANILVGENLVCKIADFGLARLIEDN-----EYTARQGAKFPIKWTAPEAALYG 446 Query: 593 RISTSGDVYSFGIVLLEMLTGKRPTDP 513 R + DV+SFGI+ E++T R P Sbjct: 447 RFTIKSDVWSFGILQTELVTKGRVPYP 473
>MAPK_FUSSO (Q00859) Mitogen-activated protein kinase (EC 2.7.11.24) (FsMAPK)| Length = 355 Score = 46.2 bits (108), Expect = 1e-04 Identities = 34/122 (27%), Positives = 54/122 (44%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 ++H DLKPSN+LL+ + + DFG+AR T + R Sbjct: 143 VLHRDLKPSNLLLNANCDLKVCDFGLARSAASQEDNSGFMTEYVATR--WYRAPEIMLTF 200 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRPTDPMFTDGLDIVNFVGSEFPHQIHEVIDIYLKGEC 417 + + DV+S G +L EML+GK P+F G ++ HQ+ ++D+ Sbjct: 201 KEYTKAIDVWSVGCILAEMLSGK----PLFP---------GKDYHHQLTLILDVLGTPTM 247 Query: 416 ED 411 ED Sbjct: 248 ED 249
>EPHA6_MOUSE (Q62413) Ephrin type-A receptor 6 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2) Length = 1035 Score = 46.2 bits (108), Expect = 1e-04 Identities = 24/85 (28%), Positives = 48/85 (56%), Gaps = 1/85 (1%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL NIL++ ++V + DFG++R+ D P ++ ++ G + Sbjct: 794 VHRDLAARNILVNSNLVCKVSDFGLSRVLEDD---PEAAYTTTGGKIPIRWTAPEAIAYR 850 Query: 593 RISTSGDVYSFGIVLLEMLT-GKRP 522 + S++ D +S+GIV+ E+++ G+RP Sbjct: 851 KFSSASDAWSYGIVMWEVMSYGERP 875
>EPHA6_HUMAN (Q9UF33) Ephrin type-A receptor 6 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2) Length = 1035 Score = 46.2 bits (108), Expect = 1e-04 Identities = 24/85 (28%), Positives = 48/85 (56%), Gaps = 1/85 (1%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL NIL++ ++V + DFG++R+ D P ++ ++ G + Sbjct: 794 VHRDLAARNILVNSNLVCKVSDFGLSRVLEDD---PEAAYTTTGGKIPIRWTAPEAIAYR 850 Query: 593 RISTSGDVYSFGIVLLEMLT-GKRP 522 + S++ D +S+GIV+ E+++ G+RP Sbjct: 851 KFSSASDAWSYGIVMWEVMSYGERP 875
>RIPK3_RAT (Q9Z2P5) Receptor-interacting serine/threonine-protein kinase 3 (EC| 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) (Homocysteine respondent protein HCYP2) Length = 478 Score = 46.2 bits (108), Expect = 1e-04 Identities = 28/83 (33%), Positives = 43/83 (51%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 ++H DLKPSN+LLD ++ A L DFG++ F + S S Sbjct: 139 LLHRDLKPSNVLLDLELHAKLADFGLS-TFQGGSQSGSGSGSRDSGGTLAYLAPELLDND 197 Query: 596 GRISTSGDVYSFGIVLLEMLTGK 528 G+ S + DVYSFG+++ +L G+ Sbjct: 198 GKASKASDVYSFGVLVWTVLAGR 220
>PKN6_MYXXA (P54738) Serine/threonine-protein kinase pkn6 (EC 2.7.11.1)| Length = 710 Score = 46.2 bits (108), Expect = 1e-04 Identities = 30/87 (34%), Positives = 41/87 (47%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 +IH D+ P NIL+ + DFGIA++ G R + V Sbjct: 139 LIHRDVSPDNILVSRQGAVKVVDFGIAKV-AGQGHRTLTGVVKGKVAYMPPEQLQAKAMD 197 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRPTD 516 R+ DVY+ G+VL E+LTGKRP D Sbjct: 198 RRV----DVYALGVVLYELLTGKRPFD 220
>PHO85_CANGA (Q6FKD4) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 302 Score = 46.2 bits (108), Expect = 1e-04 Identities = 32/83 (38%), Positives = 42/83 (50%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 I+H DLKP N+L+ LGDFG+AR F P ++ SS V Sbjct: 128 ILHRDLKPQNLLITKRGQLKLGDFGLARAF----GIPVNTFSS-EVVTLWYRAPDVLMGS 182 Query: 596 GRISTSGDVYSFGIVLLEMLTGK 528 STS D++S G +L EM+TGK Sbjct: 183 RTYSTSIDIWSCGCILAEMITGK 205
>EPHA5_CHICK (P54755) Ephrin type-A receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor CEK7) Length = 1013 Score = 46.2 bits (108), Expect = 1e-04 Identities = 24/85 (28%), Positives = 49/85 (57%), Gaps = 1/85 (1%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL NIL++ ++V + DFG++R+ D P ++ ++ G + Sbjct: 773 VHRDLAARNILINSNLVCKVSDFGLSRVLEDD---PEAAYTTRGGKIPIRWTAPEAIAFR 829 Query: 593 RISTSGDVYSFGIVLLEMLT-GKRP 522 + +++ DV+S+GIV+ E+++ G+RP Sbjct: 830 KFTSASDVWSYGIVMWEVMSYGERP 854
>TEC_HUMAN (P42680) Tyrosine-protein kinase Tec (EC 2.7.10.2)| Length = 631 Score = 46.2 bits (108), Expect = 1e-04 Identities = 30/85 (35%), Positives = 42/85 (49%), Gaps = 1/85 (1%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 IH DL N L+ + V + DFG+AR FLD TSS G + Sbjct: 486 IHRDLAARNCLVSEAGVVKVSDFGMARYFLDD-----QYTSSSGAKFPVKWCPPEVFNYS 540 Query: 593 RISTSGDVYSFGIVLLEMLT-GKRP 522 R S+ DV+SFG+++ E+ T G+ P Sbjct: 541 RFSSKSDVWSFGVLMWEVFTEGRMP 565
>MK14B_DROME (O61443) Mitogen-activated protein kinase 14B (EC 2.7.11.24) (MAP| kinase p38b) (D-p38b) Length = 365 Score = 46.2 bits (108), Expect = 1e-04 Identities = 35/133 (26%), Positives = 60/133 (45%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 +IH DLKPSNI +++D + DFG+A RPA S + V Sbjct: 149 VIHRDLKPSNIAVNEDCELRILDFGLA--------RPAESEMTGYVATRWYRAPEIMLNW 200 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRPTDPMFTDGLDIVNFVGSEFPHQIHEVIDIYLKGEC 417 + + D++S G ++ E+LTG+ F G++ HQ++ ++++ G Sbjct: 201 MHYNQTADIWSVGCIMAELLTGR-------------TLFPGTDHIHQLNLIMEVL--GTP 245 Query: 416 EDSAEARSVSEGS 378 D +R SE + Sbjct: 246 ADEFMSRISSESA 258
>YES_MOUSE (Q04736) Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2)| (p61-Yes) (c-Yes) Length = 540 Score = 46.2 bits (108), Expect = 1e-04 Identities = 27/87 (31%), Positives = 45/87 (51%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 IH DL+ +NIL+ ++++ + DFG+AR+ D+ T+ G + G Sbjct: 390 IHRDLRAANILVGENLICKIADFGLARLIEDN-----EYTARQGAKFPIKWTAPEAALYG 444 Query: 593 RISTSGDVYSFGIVLLEMLTGKRPTDP 513 R + DV+SFGI+ E++T R P Sbjct: 445 RFTIKSDVWSFGILQTELVTKGRVPYP 471
>FGR_HUMAN (P09769) Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2)| (P55-FGR) (C-FGR) Length = 529 Score = 46.2 bits (108), Expect = 1e-04 Identities = 27/83 (32%), Positives = 41/83 (49%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 IH DL+ +NIL+ + + + DFG+AR+ D P G + G Sbjct: 379 IHRDLRAANILVGERLACKIADFGLARLIKDDEYNPCQ-----GSKFPIKWTAPEAALFG 433 Query: 593 RISTSGDVYSFGIVLLEMLTGKR 525 R + DV+SFGI+L E++T R Sbjct: 434 RFTIKSDVWSFGILLTELITKGR 456
>SRC42_DROME (Q9V9J3) Tyrosine-protein kinase Src42A (EC 2.7.10.2) (Dsrc41)| Length = 517 Score = 45.8 bits (107), Expect = 1e-04 Identities = 27/91 (29%), Positives = 42/91 (46%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 IH DL N+L+ D + + DFG+AR+ + + +G R Sbjct: 367 IHRDLAARNVLVGDGNIVKIADFGLARLIKED-----EYEARVGARFPIKWTAPEAANYS 421 Query: 593 RISTSGDVYSFGIVLLEMLTGKRPTDPMFTD 501 + S DV+SFGI+L E++T R P T+ Sbjct: 422 KFSIKSDVWSFGILLTELVTYGRIPYPGMTN 452
>KPK19_ARATH (Q39030) Serine/threonine-protein kinase AtPK19 (EC 2.7.11.1)| (Ribosomal-protein S6 kinase homolog) Length = 471 Score = 45.8 bits (107), Expect = 1e-04 Identities = 32/85 (37%), Positives = 42/85 (49%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 I+H DLKP NIL+D D L DFG+A+ F ++ S S G Sbjct: 259 IMHRDLKPENILMDVDGHVMLTDFGLAKEFEEN----TRSNSMCGTTEYMAPEIVRGKGH 314 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRP 522 + + D +S GI+L EMLTGK P Sbjct: 315 DK---AADWWSVGILLYEMLTGKPP 336
>KS6A2_MOUSE (Q9WUT3) Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1)| (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (Protein-tyrosine kinase Mpk-9) (MAP kinase-activated protein kinase 1c) (M Length = 733 Score = 45.8 bits (107), Expect = 1e-04 Identities = 29/85 (34%), Positives = 42/85 (49%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 II+ DLKP NILLD++ + DFG+++ D R S +I Sbjct: 180 IIYRDLKPENILLDEEGHIKITDFGLSKEATDHDKRAYSFCGTIEYMAPEVVNRRGH--- 236 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRP 522 + S D +SFG+++ EMLTG P Sbjct: 237 ---TQSADWWSFGVLMFEMLTGSLP 258
>ST32C_MOUSE (Q8QZV4) Serine/threonine-protein kinase 32C (EC 2.7.11.1)| Length = 488 Score = 45.8 bits (107), Expect = 1e-04 Identities = 33/87 (37%), Positives = 42/87 (48%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 IIH D+KP NILLD+ AHL DF IA I D G R A++ + Sbjct: 213 IIHRDVKPDNILLDEQGHAHLTDFNIATIIKD-GER-ATALAGTKPYMAPEIFHSFVNGG 270 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRPTD 516 S D +S G++ E+L G RP D Sbjct: 271 TGYSFEVDWWSVGVMAYELLRGWRPYD 297
>ITK_HUMAN (Q08881) Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2)| (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT) Length = 620 Score = 45.8 bits (107), Expect = 1e-04 Identities = 28/86 (32%), Positives = 42/86 (48%), Gaps = 1/86 (1%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 +IH DL N L+ ++ V + DFG+ R LD TSS G + Sbjct: 478 VIHRDLAARNCLVGENQVIKVSDFGMTRFVLDD-----QYTSSTGTKFPVKWASPEVFSF 532 Query: 596 GRISTSGDVYSFGIVLLEMLT-GKRP 522 R S+ DV+SFG+++ E+ + GK P Sbjct: 533 SRYSSKSDVWSFGVLMWEVFSEGKIP 558
>EPHA5_MOUSE (Q60629) Ephrin type-A receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Brain-specific kinase) (CEK-7) Length = 877 Score = 45.8 bits (107), Expect = 1e-04 Identities = 24/85 (28%), Positives = 49/85 (57%), Gaps = 1/85 (1%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL NIL++ ++V + DFG++R+ D P ++ ++ G + Sbjct: 636 VHRDLAARNILINSNLVCKVSDFGLSRVLEDD---PEAAYTTRGGKIPIRWTAPEAIAFR 692 Query: 593 RISTSGDVYSFGIVLLEMLT-GKRP 522 + +++ DV+S+GIV+ E+++ G+RP Sbjct: 693 KFTSASDVWSYGIVMWEVVSYGERP 717
>EPHA5_HUMAN (P54756) Ephrin type-A receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Receptor protein-tyrosine kinase HEK7) Length = 1037 Score = 45.8 bits (107), Expect = 1e-04 Identities = 24/85 (28%), Positives = 49/85 (57%), Gaps = 1/85 (1%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL NIL++ ++V + DFG++R+ D P ++ ++ G + Sbjct: 797 VHRDLAARNILINSNLVCKVSDFGLSRVLEDD---PEAAYTTRGGKIPIRWTAPEAIAFR 853 Query: 593 RISTSGDVYSFGIVLLEMLT-GKRP 522 + +++ DV+S+GIV+ E+++ G+RP Sbjct: 854 KFTSASDVWSYGIVMWEVVSYGERP 878
>KSS1_YEAST (P14681) Mitogen-activated protein kinase KSS1 (EC 2.7.11.24) (MAP| kinase KSS1) (Kinase suppressor of SST2) Length = 368 Score = 45.8 bits (107), Expect = 1e-04 Identities = 35/133 (26%), Positives = 61/133 (45%), Gaps = 5/133 (3%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIG-----VRXXXXXXXX 612 +IH D+KPSN+LL+ + + DFG+AR S S + +G V Sbjct: 139 VIHRDIKPSNLLLNSNCDLKVCDFGLARCLASSSD---SRETLVGFMTEYVATRWYRAPE 195 Query: 611 XXXXXGRISTSGDVYSFGIVLLEMLTGKRPTDPMFTDGLDIVNFVGSEFPHQIHEVIDIY 432 +T+ D++S G +L EM++GK P+F G ++ HQ+ ++++ Sbjct: 196 IMLTFQEYTTAMDIWSCGCILAEMVSGK----PLFP---------GRDYHHQLWLILEVL 242 Query: 431 LKGECEDSAEARS 393 ED + +S Sbjct: 243 GTPSFEDFNQIKS 255
>EPHA5_RAT (P54757) Ephrin type-A receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) Length = 1005 Score = 45.8 bits (107), Expect = 1e-04 Identities = 24/85 (28%), Positives = 49/85 (57%), Gaps = 1/85 (1%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL NIL++ ++V + DFG++R+ D P ++ ++ G + Sbjct: 799 VHRDLAARNILINSNLVCKVSDFGLSRVLEDD---PEAAYTTRGGKIPIRWTAPEAIAFR 855 Query: 593 RISTSGDVYSFGIVLLEMLT-GKRP 522 + +++ DV+S+GIV+ E+++ G+RP Sbjct: 856 KFTSASDVWSYGIVMWEVVSYGERP 880
>ITK_MOUSE (Q03526) Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2)| (T-cell-specific kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK) Length = 625 Score = 45.8 bits (107), Expect = 1e-04 Identities = 28/86 (32%), Positives = 42/86 (48%), Gaps = 1/86 (1%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 +IH DL N L+ ++ V + DFG+ R LD TSS G + Sbjct: 483 VIHRDLAARNCLVGENQVIKVSDFGMTRFVLDD-----QYTSSTGTKFPVKWASPEVFSF 537 Query: 596 GRISTSGDVYSFGIVLLEMLT-GKRP 522 R S+ DV+SFG+++ E+ + GK P Sbjct: 538 SRYSSKSDVWSFGVLMWEVFSEGKIP 563
>MP2K2_XENLA (Q07192) Dual specificity mitogen-activated protein kinase kinase 2| (EC 2.7.12.2) (MAP kinase kinase 2) (MAPKK 2) (MAPK-ERK kinase 2) (Fragment) Length = 446 Score = 45.8 bits (107), Expect = 1e-04 Identities = 32/86 (37%), Positives = 41/86 (47%), Gaps = 1/86 (1%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 IIH D+KPSNILLD + L DFGI+ +DS + T G R Sbjct: 272 IIHRDIKPSNILLDTNGNIKLCDFGISGQLVDS----IAKTRDAGCRPYMAPERIDPSAS 327 Query: 596 GR-ISTSGDVYSFGIVLLEMLTGKRP 522 + DV+S GI L E+ TG+ P Sbjct: 328 RQGYDVRSDVWSLGITLYELATGRFP 353
>MATK_MOUSE (P41242) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK) Length = 505 Score = 45.8 bits (107), Expect = 1e-04 Identities = 32/93 (34%), Positives = 49/93 (52%), Gaps = 4/93 (4%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIA---RIFLDSGPRPASSTSSIGVRXXXXXXXXXX 606 ++H DL NIL+ +D+VA + DFG+A R LDS P T+ ++ Sbjct: 346 LVHRDLAARNILVSEDLVAKVSDFGLAKAERKGLDSSRLPVKWTAPEALK---------- 395 Query: 605 XXXGRISTSGDVYSFGIVLLEMLT-GKRPTDPM 510 GR S+ DV+SFG++L E+ + G+ P M Sbjct: 396 --NGRFSSKSDVWSFGVLLWEVFSYGRAPYPKM 426
>YES_CANFA (Q28923) Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2)| (p61-Yes) (c-Yes) Length = 538 Score = 45.8 bits (107), Expect = 1e-04 Identities = 28/87 (32%), Positives = 44/87 (50%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 IH DL+ +NIL+ +++V + DFG+AR+ D+ T+ G + G Sbjct: 388 IHRDLRAANILVGENLVCKIADFGLARLIEDN-----EYTARQGAKFPIKWTAPEAALYG 442 Query: 593 RISTSGDVYSFGIVLLEMLTGKRPTDP 513 R + DV+SFGI+ E+ T R P Sbjct: 443 RFTIKSDVWSFGILQTELTTKGRVPYP 469
>SPKA_SYNY3 (Q9FAB3) Serine/threonine-protein kinase A (EC 2.7.11.1)| Length = 521 Score = 45.8 bits (107), Expect = 1e-04 Identities = 26/92 (28%), Positives = 45/92 (48%), Gaps = 4/92 (4%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDM----VAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXX 609 ++H D+KPSN+LL +D + + DFGIA++ + A + + Sbjct: 144 VVHRDIKPSNVLLVEDPALGELVKILDFGIAKLV-----QAAEESKTQAFMGTLAYCSPE 198 Query: 608 XXXXGRISTSGDVYSFGIVLLEMLTGKRPTDP 513 + + D+YS G+++ EMLTG+ P P Sbjct: 199 QMEGKELDSRSDIYSLGVMMYEMLTGEMPLFP 230
>RAF1_XENLA (P09560) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (C-RAF) Length = 638 Score = 45.4 bits (106), Expect = 2e-04 Identities = 29/86 (33%), Positives = 42/86 (48%), Gaps = 1/86 (1%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLD-SGPRPASSTSSIGVRXXXXXXXXXXXX 600 IIH D+K +NI L + + +GDFG+A + SG + + G Sbjct: 455 IIHRDMKSNNIFLHEGLTVKIGDFGLATVKTRWSGSQQVEQLT--GSILWMAPEVIRMQD 512 Query: 599 XGRISTSGDVYSFGIVLLEMLTGKRP 522 S DVYS+GIVL E++TG+ P Sbjct: 513 NNPFSFQSDVYSYGIVLYELMTGELP 538
>HCK_MOUSE (P08103) Tyrosine-protein kinase HCK (EC 2.7.10.2)| (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK) Length = 523 Score = 45.4 bits (106), Expect = 2e-04 Identities = 27/80 (33%), Positives = 42/80 (52%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 IH DL+ +NIL+ +V + DFG+ARI D+ T+ G + G Sbjct: 375 IHRDLRAANILVSASLVCKIADFGLARIIEDN-----EYTAREGAKFPIKWTAPEAINFG 429 Query: 593 RISTSGDVYSFGIVLLEMLT 534 + DV+SFGI+L+E++T Sbjct: 430 SFTIKSDVWSFGILLMEIVT 449
>PKH1_YEAST (Q03407) Serine/threonine-protein kinase PKH1 (EC 2.7.11.1)| (3-phosphoinositide-dependent protein kinase 1) Length = 766 Score = 45.4 bits (106), Expect = 2e-04 Identities = 31/95 (32%), Positives = 42/95 (44%), Gaps = 10/95 (10%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRP----------ASSTSSIGVRXXX 627 IIH D+KP NILLD +M L DFG A+I + A S S +G Sbjct: 245 IIHRDIKPENILLDKNMKVKLTDFGTAKILPEEPSNTADGKPYFDLYAKSKSFVGTAEYV 304 Query: 626 XXXXXXXXXXGRISTSGDVYSFGIVLLEMLTGKRP 522 + D+++FG +L +ML GK P Sbjct: 305 SPELLNDNYT---DSRCDIWAFGCILYQMLAGKPP 336
>KS6A3_MOUSE (P18654) Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1)| (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (MAP kinase-activated protein kinase 1b) (MAPKAPK1B) Length = 740 Score = 45.4 bits (106), Expect = 2e-04 Identities = 28/85 (32%), Positives = 43/85 (50%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 II+ DLKP NILLD++ L DFG+++ +D + S ++ Sbjct: 189 IIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGH--- 245 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRP 522 + S D +SFG+++ EMLTG P Sbjct: 246 ---TQSADWWSFGVLMFEMLTGTLP 267
>KS6A3_HUMAN (P51812) Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1)| (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protei Length = 740 Score = 45.4 bits (106), Expect = 2e-04 Identities = 28/85 (32%), Positives = 43/85 (50%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 II+ DLKP NILLD++ L DFG+++ +D + S ++ Sbjct: 189 IIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGH--- 245 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRP 522 + S D +SFG+++ EMLTG P Sbjct: 246 ---TQSADWWSFGVLMFEMLTGTLP 267
>HCK_RAT (P50545) Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK)| (Hemopoietic cell kinase) Length = 502 Score = 45.4 bits (106), Expect = 2e-04 Identities = 27/80 (33%), Positives = 42/80 (52%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 IH DL+ +NIL+ +V + DFG+ARI D+ T+ G + G Sbjct: 354 IHRDLRAANILVSASLVCKIADFGLARIIEDN-----EYTAREGAKFPIKWTAPEAINFG 408 Query: 593 RISTSGDVYSFGIVLLEMLT 534 + DV+SFGI+L+E++T Sbjct: 409 SFTIKSDVWSFGILLMEIVT 428
>EPHA3_CHICK (P29318) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ETK1) (CEK4) Length = 983 Score = 45.4 bits (106), Expect = 2e-04 Identities = 24/85 (28%), Positives = 48/85 (56%), Gaps = 1/85 (1%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL NIL++ ++V + DFG++R+ D P ++ ++ G + Sbjct: 743 VHRDLAARNILINSNLVCKVSDFGLSRVLEDD---PEAAYTTRGGKIPIRWTSPEAIAYR 799 Query: 593 RISTSGDVYSFGIVLLEMLT-GKRP 522 + +++ D +S+GIVL E+++ G+RP Sbjct: 800 KFTSASDAWSYGIVLWEVMSYGERP 824
>PKN1_COREF (Q8FUI5) Probable serine/threonine protein kinase CE0033 (EC| 2.7.11.1) Length = 660 Score = 45.4 bits (106), Expect = 2e-04 Identities = 28/85 (32%), Positives = 42/85 (49%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 IIH D+KP+NI++++ + DFGIAR DS ++ T + V Sbjct: 132 IIHRDVKPANIMINNTGGVKVMDFGIARALDDS---TSAMTQTAAVIGTAQYLSPEQARG 188 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRP 522 DVY+ G VL E++TG+ P Sbjct: 189 KPADARSDVYAAGCVLYELVTGRPP 213
>MATK_RAT (P41243) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase BATK) Length = 467 Score = 45.4 bits (106), Expect = 2e-04 Identities = 32/94 (34%), Positives = 49/94 (52%), Gaps = 5/94 (5%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIA----RIFLDSGPRPASSTSSIGVRXXXXXXXXX 609 ++H DL NIL+ +D+VA + DFG+A R LDS P T+ ++ Sbjct: 307 LVHRDLAARNILVSEDLVAKVSDFGLAKAELRKGLDSSRLPVKWTAPEALK--------- 357 Query: 608 XXXXGRISTSGDVYSFGIVLLEMLT-GKRPTDPM 510 GR S+ DV+SFG++L E+ + G+ P M Sbjct: 358 ---NGRFSSKSDVWSFGVLLWEVFSYGRAPYPKM 388
>PDPK1_RAT (O55173) 3-phosphoinositide-dependent protein kinase 1 (EC| 2.7.11.1) (Protein kinase B kinase) (PkB kinase) Length = 559 Score = 45.4 bits (106), Expect = 2e-04 Identities = 26/85 (30%), Positives = 43/85 (50%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 IIH DLKP NILL++DM + DFG A++ L + A + S +G Sbjct: 204 IIHRDLKPENILLNEDMHIQITDFGTAKV-LSPDSKQARANSFVGTAQYVSPELLTEKSA 262 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRP 522 + S D+++ G ++ +++ G P Sbjct: 263 CK---SSDLWALGCIIYQLVAGLPP 284
>EPHA4_MOUSE (Q03137) Ephrin type-A receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor SEK) (MPK-3) Length = 986 Score = 45.4 bits (106), Expect = 2e-04 Identities = 24/85 (28%), Positives = 49/85 (57%), Gaps = 1/85 (1%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL NIL++ ++V + DFG++R+ D P ++ ++ G + Sbjct: 743 VHRDLAARNILVNSNLVCKVSDFGMSRVLEDD---PEAAYTTRGGKIPIRWTAPEAIAYR 799 Query: 593 RISTSGDVYSFGIVLLEMLT-GKRP 522 + +++ DV+S+GIV+ E+++ G+RP Sbjct: 800 KFTSASDVWSYGIVMWEVMSYGERP 824
>EPHA4_HUMAN (P54764) Ephrin type-A receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8) Length = 986 Score = 45.4 bits (106), Expect = 2e-04 Identities = 24/85 (28%), Positives = 49/85 (57%), Gaps = 1/85 (1%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL NIL++ ++V + DFG++R+ D P ++ ++ G + Sbjct: 743 VHRDLAARNILVNSNLVCKVSDFGMSRVLEDD---PEAAYTTRGGKIPIRWTAPEAIAYR 799 Query: 593 RISTSGDVYSFGIVLLEMLT-GKRP 522 + +++ DV+S+GIV+ E+++ G+RP Sbjct: 800 KFTSASDVWSYGIVMWEVMSYGERP 824
>EPHA4_CHICK (Q07496) Ephrin type-A receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor CEK8) Length = 986 Score = 45.4 bits (106), Expect = 2e-04 Identities = 24/85 (28%), Positives = 49/85 (57%), Gaps = 1/85 (1%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL NIL++ ++V + DFG++R+ D P ++ ++ G + Sbjct: 743 VHRDLAARNILVNSNLVCKVSDFGMSRVLEDD---PEAAYTTRGGKIPIRWTAPEAIAYR 799 Query: 593 RISTSGDVYSFGIVLLEMLT-GKRP 522 + +++ DV+S+GIV+ E+++ G+RP Sbjct: 800 KFTSASDVWSYGIVMWEVMSYGERP 824
>EPA4A_XENLA (Q91845) Ephrin type-A receptor 4-A precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor SEK-1) (xSEK-1) Length = 986 Score = 45.4 bits (106), Expect = 2e-04 Identities = 24/85 (28%), Positives = 49/85 (57%), Gaps = 1/85 (1%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL NIL++ ++V + DFG++R+ D P ++ ++ G + Sbjct: 742 VHRDLAARNILVNSNLVCKVSDFGMSRVLEDD---PEAAYTTRGGKIPIRWTAPEAIAYR 798 Query: 593 RISTSGDVYSFGIVLLEMLT-GKRP 522 + +++ DV+S+GIV+ E+++ G+RP Sbjct: 799 KFTSASDVWSYGIVMWEVMSYGERP 823
>EPA4B_XENLA (Q91694) Ephrin type-A receptor 4-B precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor PAG) (Pagliaccio) Length = 985 Score = 45.4 bits (106), Expect = 2e-04 Identities = 24/85 (28%), Positives = 49/85 (57%), Gaps = 1/85 (1%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL NIL++ ++V + DFG++R+ D P ++ ++ G + Sbjct: 742 VHRDLAARNILVNSNLVCKVSDFGMSRVLEDD---PEAAYTTRGGKIPIRWTAPEAIAYR 798 Query: 593 RISTSGDVYSFGIVLLEMLT-GKRP 522 + +++ DV+S+GIV+ E+++ G+RP Sbjct: 799 KFTSASDVWSYGIVMWEVMSYGERP 823
>LCK_MOUSE (P06240) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) Length = 508 Score = 45.4 bits (106), Expect = 2e-04 Identities = 29/91 (31%), Positives = 45/91 (49%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 IH DL+ +NIL+ D + + DFG+AR+ D+ T+ G + G Sbjct: 360 IHRDLRAANILVSDTLSCKIADFGLARLIEDN-----EYTAREGAKFPIKWTAPEAINYG 414 Query: 593 RISTSGDVYSFGIVLLEMLTGKRPTDPMFTD 501 + DV+SFGI+L E++T R P T+ Sbjct: 415 TFTIKSDVWSFGILLTEIVTHGRIPYPGMTN 445
>LCK_HUMAN (P06239) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell-specific protein-tyrosine kinase) Length = 508 Score = 45.4 bits (106), Expect = 2e-04 Identities = 29/91 (31%), Positives = 45/91 (49%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 IH DL+ +NIL+ D + + DFG+AR+ D+ T+ G + G Sbjct: 360 IHRDLRAANILVSDTLSCKIADFGLARLIEDN-----EYTAREGAKFPIKWTAPEAINYG 414 Query: 593 RISTSGDVYSFGIVLLEMLTGKRPTDPMFTD 501 + DV+SFGI+L E++T R P T+ Sbjct: 415 TFTIKSDVWSFGILLTEIVTHGRIPYPGMTN 445
>LCK_AOTNA (Q5PXS1) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) Length = 508 Score = 45.4 bits (106), Expect = 2e-04 Identities = 29/91 (31%), Positives = 45/91 (49%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 IH DL+ +NIL+ D + + DFG+AR+ D+ T+ G + G Sbjct: 360 IHRDLRAANILVSDTLSCKIADFGLARLIEDN-----EYTAREGAKFPIKWTAPEAINYG 414 Query: 593 RISTSGDVYSFGIVLLEMLTGKRPTDPMFTD 501 + DV+SFGI+L E++T R P T+ Sbjct: 415 TFTIKSDVWSFGILLTEIVTHGRIPYPGMTN 445
>KS6AA_XENLA (P10665) Ribosomal protein S6 kinase 2 alpha (EC 2.7.11.1)| (Ribosomal protein S6 kinase II alpha) (S6KII-alpha) (P90-RSK) (MAP kinase-activated protein kinase 1) (MAPK-activated protein kinase 1) (MAPKAP kinase 1) (MAPKAPK-1) Length = 733 Score = 45.4 bits (106), Expect = 2e-04 Identities = 28/85 (32%), Positives = 43/85 (50%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 II+ DLKP NILLD++ L DFG+++ +D + S ++ Sbjct: 183 IIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQGH--- 239 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRP 522 S S D +S+G+++ EMLTG P Sbjct: 240 ---SHSADWWSYGVLMFEMLTGSLP 261
>KS6AA_CHICK (P18652) Ribosomal protein S6 kinase 2 alpha (EC 2.7.11.1)| (Ribosomal protein S6 kinase II alpha) (S6KII-alpha) (P90-RSK) (MAP kinase-activated protein kinase 1) (MAPK-activated protein kinase 1) (MAPKAP kinase 1) (MAPKAPK-1) Length = 752 Score = 45.4 bits (106), Expect = 2e-04 Identities = 28/85 (32%), Positives = 43/85 (50%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 II+ DLKP NILLD++ L DFG+++ +D + S ++ Sbjct: 201 IIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQGH--- 257 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRP 522 S S D +S+G+++ EMLTG P Sbjct: 258 ---SHSADWWSYGVLMFEMLTGSLP 279
>KS6A1_HUMAN (Q15418) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 735 Score = 45.4 bits (106), Expect = 2e-04 Identities = 28/85 (32%), Positives = 43/85 (50%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 II+ DLKP NILLD++ L DFG+++ +D + S ++ Sbjct: 183 IIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQGH--- 239 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRP 522 S S D +S+G+++ EMLTG P Sbjct: 240 ---SHSADWWSYGVLMFEMLTGSLP 261
>SRC64_DROME (P00528) Tyrosine-protein kinase Src64B (EC 2.7.10.2) (Dsrc64)| Length = 552 Score = 45.4 bits (106), Expect = 2e-04 Identities = 27/81 (33%), Positives = 41/81 (50%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 +IH DL N+L+ ++ VA + DFG+AR+ D P G R Sbjct: 400 LIHRDLAARNVLIGENNVAKICDFGLARVIADDEYCPKQ-----GSRFPVKWTAPEAIIY 454 Query: 596 GRISTSGDVYSFGIVLLEMLT 534 G+ S DV+S+GI+L+E+ T Sbjct: 455 GKFSIKSDVWSYGILLMELFT 475
>RAF1_CHICK (P05625) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (RAF-1) (C-RAF) (MIL proto-oncogene serine/threonine-protein kinase) (C-MIL) Length = 647 Score = 45.4 bits (106), Expect = 2e-04 Identities = 29/86 (33%), Positives = 42/86 (48%), Gaps = 1/86 (1%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLD-SGPRPASSTSSIGVRXXXXXXXXXXXX 600 IIH D+K +NI L + + +GDFG+A + SG + + G Sbjct: 464 IIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPT--GSILWMAPEVIRMQD 521 Query: 599 XGRISTSGDVYSFGIVLLEMLTGKRP 522 S DVYS+GIVL E++TG+ P Sbjct: 522 SNPFSFQSDVYSYGIVLYELMTGELP 547
>SPK1_SCHPO (P27638) Mitogen-activated protein kinase spk1 (EC 2.7.11.24) (MAP| kinase spk1) (MAPK) Length = 372 Score = 45.1 bits (105), Expect = 3e-04 Identities = 34/128 (26%), Positives = 57/128 (44%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 ++H DLKPSN+LL+ + + DFG+AR G P T + R Sbjct: 159 VVHRDLKPSNLLLNANCDLKVADFGLARSTTAQGGNPGFMTEYVATR--WYRAPEIMLSF 216 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRPTDPMFTDGLDIVNFVGSEFPHQIHEVIDIYLKGEC 417 S + D++S G +L EML+ + P+F G ++ QI +++I Sbjct: 217 REYSKAIDLWSTGCILAEMLSAR----PLFP---------GKDYHSQITLILNILGTPTM 263 Query: 416 EDSAEARS 393 +D + +S Sbjct: 264 DDFSRIKS 271
>TSSK1_MOUSE (Q61241) Testis-specific serine/threonine-protein kinase 1 (EC| 2.7.11.1) (TSSK-1) (Testis-specific kinase 1) (TSK-1) (Serine/threonine-protein kinase 22A) Length = 364 Score = 45.1 bits (105), Expect = 3e-04 Identities = 37/124 (29%), Positives = 50/124 (40%), Gaps = 2/124 (1%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFL--DSGPRPASSTSSIGVRXXXXXXXXXXX 603 ++H DLK N+LLD D L DFG ++ L DSG S T Sbjct: 132 VVHRDLKSENLLLDKDFNIKLSDFGFSKRCLRDDSGRLILSKTFCGSAAYAAPEVLQGIP 191 Query: 602 XXGRISTSGDVYSFGIVLLEMLTGKRPTDPMFTDGLDIVNFVGSEFPHQIHEVIDIYLKG 423 ++ D++S G++L M+ G P D L I FP H L G Sbjct: 192 YQPKVY---DIWSLGVILYIMVCGSMPYDDSNIKKLRIQKEHRVNFPRSKH------LTG 242 Query: 422 ECED 411 EC+D Sbjct: 243 ECKD 246
>HCK_HUMAN (P08631) Tyrosine-protein kinase HCK (EC 2.7.10.2)| (p59-HCK/p60-HCK) (Hemopoietic cell kinase) Length = 525 Score = 45.1 bits (105), Expect = 3e-04 Identities = 26/80 (32%), Positives = 42/80 (52%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 IH DL+ +NIL+ +V + DFG+AR+ D+ T+ G + G Sbjct: 377 IHRDLRAANILVSASLVCKIADFGLARVIEDN-----EYTAREGAKFPIKWTAPEAINFG 431 Query: 593 RISTSGDVYSFGIVLLEMLT 534 + DV+SFGI+L+E++T Sbjct: 432 SFTIKSDVWSFGILLMEIVT 451
>EPHA7_CHICK (O42422) Ephrin type-A receptor 7 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor CEPHA7) (Tyrosine-protein kinase receptor CEK11) Length = 993 Score = 45.1 bits (105), Expect = 3e-04 Identities = 24/85 (28%), Positives = 48/85 (56%), Gaps = 1/85 (1%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL NIL++ ++V + DFG++R+ D P + ++ G + Sbjct: 750 VHRDLAARNILVNSNLVCKVSDFGLSRVIEDD---PEAVYTTTGGKIPVRWTAPEAIQYR 806 Query: 593 RISTSGDVYSFGIVLLEMLT-GKRP 522 + +++ DV+S+GIV+ E+++ G+RP Sbjct: 807 KFTSASDVWSYGIVMWEVMSYGERP 831
>PK1_STRTO (Q9KIG4) Serine/threonine-protein kinase PK-1 (EC 2.7.11.1)| (stoPK-1) Length = 641 Score = 45.1 bits (105), Expect = 3e-04 Identities = 30/87 (34%), Positives = 42/87 (48%), Gaps = 1/87 (1%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIG-VRXXXXXXXXXXXXX 597 +H D+KP N+L+ DD + DFG+ R S T++ G V Sbjct: 138 VHRDMKPENVLIGDDGRVKVADFGLVRAV-------DSVTNTTGTVLGTVSYLAPEQIEH 190 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRPTD 516 G DVY+ GI+L EMLTG++P D Sbjct: 191 GTADPRVDVYACGILLYEMLTGEKPHD 217
>PKN2_COREF (Q8FUI4) Serine/threonine protein kinases drp72 (EC 2.7.11.1)| Length = 520 Score = 45.1 bits (105), Expect = 3e-04 Identities = 26/85 (30%), Positives = 44/85 (51%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 ++H D+KP N+L+ + + + DFGIA+ + P + T V Sbjct: 144 LVHRDIKPGNMLITANGILKITDFGIAKA---AASVPLTRTGM--VVGTAQYVSPEQAQG 198 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRP 522 +++ + DVYS G+V EML+G+RP Sbjct: 199 HQVTPASDVYSLGVVGYEMLSGRRP 223
>MP2K4_HUMAN (P45985) Dual specificity mitogen-activated protein kinase kinase 4| (EC 2.7.12.2) (MAP kinase kinase 4) (JNK-activating kinase 1) (c-Jun N-terminal kinase kinase 1) (JNKK) (SAPK/ERK kinase 1) (SEK1) Length = 399 Score = 45.1 bits (105), Expect = 3e-04 Identities = 32/86 (37%), Positives = 40/86 (46%), Gaps = 1/86 (1%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 IIH D+KPSNILLD L DFGI+ +DS + T G R Sbjct: 225 IIHRDIKPSNILLDRSGNIKLCDFGISGQLVDS----IAKTRDAGCRPYMAPERIDPSAS 280 Query: 596 GR-ISTSGDVYSFGIVLLEMLTGKRP 522 + DV+S GI L E+ TG+ P Sbjct: 281 RQGYDVRSDVWSLGITLYELATGRFP 306
>EPHA3_BRARE (O13146) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ZEK1) (EPH-like kinase 1) Length = 981 Score = 45.1 bits (105), Expect = 3e-04 Identities = 24/85 (28%), Positives = 49/85 (57%), Gaps = 1/85 (1%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL NIL++ ++V + DFG++R+ D P ++ ++ G + Sbjct: 748 VHRDLAARNILVNRNLVCKVSDFGLSRVLEDD---PEAAYTTRGGKIPIRWTAPEAITYR 804 Query: 593 RISTSGDVYSFGIVLLEMLT-GKRP 522 + +++ DV+S+GIV+ E+++ G+RP Sbjct: 805 KFTSASDVWSYGIVMWEVISYGERP 829
>KGP25_DROME (P32023) cGMP-dependent protein kinase, isozyme 2 forms cD5/T2 (EC| 2.7.11.12) (CGK) (Foraging protein) Length = 934 Score = 45.1 bits (105), Expect = 3e-04 Identities = 39/140 (27%), Positives = 60/140 (42%), Gaps = 4/140 (2%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 II+ DLKP N+LL++ L DFG A+ L +G + + + Sbjct: 743 IIYRDLKPENLLLNERGYVKLVDFGFAKK-LQTGRKTWTFCGT------PEYVAPEVILN 795 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRP---TDPMFTDGLDIVNFVGSEFPHQIHEVIDIYLK 426 S D +S G+++ E+LTG P +DPM T + + EFP I +K Sbjct: 796 RGHDISADYWSLGVLMFELLTGTPPFTGSDPMRTYNIILKGIDAIEFPRNITRNASNLIK 855 Query: 425 GECEDS-AEARSVSEGSVHQ 369 C D+ AE G + + Sbjct: 856 KLCRDNPAERLGYQRGGISE 875
>ST32C_HUMAN (Q86UX6) Serine/threonine-protein kinase 32C (EC 2.7.11.1) (PKE)| (YANK3) Length = 486 Score = 45.1 bits (105), Expect = 3e-04 Identities = 33/87 (37%), Positives = 42/87 (48%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 IIH D+KP NILLD+ AHL DF IA I D G R A++ + Sbjct: 212 IIHRDVKPDNILLDERGHAHLTDFNIATIIKD-GER-ATALAGTKPYMAPEIFHSFVNGG 269 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRPTD 516 S D +S G++ E+L G RP D Sbjct: 270 TGYSFEVDWWSVGVMAYELLRGWRPYD 296
>RAF1_RAT (P11345) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Raf-1) (C-RAF) (cRaf) Length = 648 Score = 45.1 bits (105), Expect = 3e-04 Identities = 29/86 (33%), Positives = 42/86 (48%), Gaps = 1/86 (1%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLD-SGPRPASSTSSIGVRXXXXXXXXXXXX 600 IIH D+K +NI L + + +GDFG+A + SG + + G Sbjct: 464 IIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPT--GSVLWMAPEVIRMQD 521 Query: 599 XGRISTSGDVYSFGIVLLEMLTGKRP 522 S DVYS+GIVL E++TG+ P Sbjct: 522 NNPFSFQSDVYSYGIVLYELMTGELP 547
>RAF1_HUMAN (P04049) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Raf-1) (C-RAF) (cRaf) Length = 648 Score = 45.1 bits (105), Expect = 3e-04 Identities = 29/86 (33%), Positives = 42/86 (48%), Gaps = 1/86 (1%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLD-SGPRPASSTSSIGVRXXXXXXXXXXXX 600 IIH D+K +NI L + + +GDFG+A + SG + + G Sbjct: 464 IIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPT--GSVLWMAPEVIRMQD 521 Query: 599 XGRISTSGDVYSFGIVLLEMLTGKRP 522 S DVYS+GIVL E++TG+ P Sbjct: 522 NNPFSFQSDVYSYGIVLYELMTGELP 547
>MP2K4_MOUSE (P47809) Dual specificity mitogen-activated protein kinase kinase 4| (EC 2.7.12.2) (MAP kinase kinase 4) (MAPKK 4) (MAPK/ERK kinase 4) (JNK-activating kinase 1) (C-JUN N-terminal kinase kinase 1) (JNK kinase 1) (JNKK 1) (SAPK/ERK kinase 1) (SE Length = 397 Score = 45.1 bits (105), Expect = 3e-04 Identities = 32/86 (37%), Positives = 40/86 (46%), Gaps = 1/86 (1%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 IIH D+KPSNILLD L DFGI+ +DS + T G R Sbjct: 223 IIHRDIKPSNILLDRSGNIKLCDFGISGQLVDS----IAKTRDAGCRPYMAPERIDPSAS 278 Query: 596 GR-ISTSGDVYSFGIVLLEMLTGKRP 522 + DV+S GI L E+ TG+ P Sbjct: 279 RQGYDVRSDVWSLGITLYELATGRFP 304
>PDPK1_MOUSE (Q9Z2A0) 3-phosphoinositide-dependent protein kinase 1 (EC| 2.7.11.1) (mPDK1) Length = 559 Score = 45.1 bits (105), Expect = 3e-04 Identities = 26/85 (30%), Positives = 43/85 (50%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 IIH DLKP NILL++DM + DFG A++ L + A + S +G Sbjct: 204 IIHRDLKPENILLNEDMHIQITDFGTAKV-LSPESKQARANSFVGTAQYVSPELLTEKSA 262 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRP 522 + S D+++ G ++ +++ G P Sbjct: 263 CK---SSDLWALGCIIYQLVAGLPP 284
>MP2K1_XENLA (Q05116) Dual specificity mitogen-activated protein kinase kinase 1| (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) Length = 394 Score = 45.1 bits (105), Expect = 3e-04 Identities = 29/97 (29%), Positives = 46/97 (47%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 I+H D+KPSNIL++ L DFG++ +DS + S +G R Sbjct: 185 IMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDS-----MANSFVGTR---SYMSPERLQG 236 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRPTDPMFTDGLDIV 486 S D++S G+ L+EM G+ P P L+++ Sbjct: 237 THYSVQSDIWSMGLSLVEMAIGRYPIPPPDAKELELI 273
>DSOR1_DROME (Q24324) Dual specificity mitogen-activated protein kinase kinase| dSOR1 (EC 2.7.12.2) (Downstream of RAF) (MAPKK) Length = 396 Score = 45.1 bits (105), Expect = 3e-04 Identities = 30/97 (30%), Positives = 45/97 (46%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 IIH D+KPSNIL++ + DFG++ +DS + S +G R Sbjct: 205 IIHRDVKPSNILVNSSGEIKICDFGVSGQLIDS-----MANSFVGTR---SYMSPERLQG 256 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRPTDPMFTDGLDIV 486 S D++S G+ L+EM G P P T L+ + Sbjct: 257 THYSVQSDIWSLGLSLVEMAIGMYPIPPPNTATLESI 293
>PDPK1_HUMAN (O15530) 3-phosphoinositide-dependent protein kinase 1 (EC| 2.7.11.1) (hPDK1) Length = 556 Score = 45.1 bits (105), Expect = 3e-04 Identities = 26/85 (30%), Positives = 43/85 (50%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 IIH DLKP NILL++DM + DFG A++ L + A + S +G Sbjct: 201 IIHRDLKPENILLNEDMHIQITDFGTAKV-LSPESKQARANSFVGTAQYVSPELLTEKSA 259 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRP 522 + S D+++ G ++ +++ G P Sbjct: 260 CK---SSDLWALGCIIYQLVAGLPP 281
>KGP24_DROME (Q03043) cGMP-dependent protein kinase, isozyme 2 forms| cD4/T1/T3A/T3B (EC 2.7.11.12) (CGK) (Foraging protein) Length = 1088 Score = 45.1 bits (105), Expect = 3e-04 Identities = 39/140 (27%), Positives = 60/140 (42%), Gaps = 4/140 (2%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 II+ DLKP N+LL++ L DFG A+ L +G + + + Sbjct: 897 IIYRDLKPENLLLNERGYVKLVDFGFAKK-LQTGRKTWTFCGT------PEYVAPEVILN 949 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRP---TDPMFTDGLDIVNFVGSEFPHQIHEVIDIYLK 426 S D +S G+++ E+LTG P +DPM T + + EFP I +K Sbjct: 950 RGHDISADYWSLGVLMFELLTGTPPFTGSDPMRTYNIILKGIDAIEFPRNITRNASNLIK 1009 Query: 425 GECEDS-AEARSVSEGSVHQ 369 C D+ AE G + + Sbjct: 1010 KLCRDNPAERLGYQRGGISE 1029
>EPHA7_RAT (P54759) Ephrin type-A receptor 7 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) Length = 998 Score = 45.1 bits (105), Expect = 3e-04 Identities = 24/85 (28%), Positives = 48/85 (56%), Gaps = 1/85 (1%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL NIL++ ++V + DFG++R+ D P + ++ G + Sbjct: 755 VHRDLAARNILVNSNLVCKVSDFGLSRVIEDD---PEAVYTTTGGKIPVRWTAPEAIQYR 811 Query: 593 RISTSGDVYSFGIVLLEMLT-GKRP 522 + +++ DV+S+GIV+ E+++ G+RP Sbjct: 812 KFTSASDVWSYGIVMWEVMSYGERP 836
>EPHA7_MOUSE (Q61772) Ephrin type-A receptor 7 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Embryonic brain kinase) (EBK) (Developmental kinase 1) (MDK-1) Length = 998 Score = 45.1 bits (105), Expect = 3e-04 Identities = 24/85 (28%), Positives = 48/85 (56%), Gaps = 1/85 (1%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL NIL++ ++V + DFG++R+ D P + ++ G + Sbjct: 755 VHRDLAARNILVNSNLVCKVSDFGLSRVIEDD---PEAVYTTTGGKIPVRWTAPEAIQYR 811 Query: 593 RISTSGDVYSFGIVLLEMLT-GKRP 522 + +++ DV+S+GIV+ E+++ G+RP Sbjct: 812 KFTSASDVWSYGIVMWEVMSYGERP 836
>EPHA7_HUMAN (Q15375) Ephrin type-A receptor 7 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Receptor protein-tyrosine kinase HEK11) Length = 998 Score = 45.1 bits (105), Expect = 3e-04 Identities = 24/85 (28%), Positives = 48/85 (56%), Gaps = 1/85 (1%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +H DL NIL++ ++V + DFG++R+ D P + ++ G + Sbjct: 755 VHRDLAARNILVNSNLVCKVSDFGLSRVIEDD---PEAVYTTTGGKIPVRWTAPEAIQYR 811 Query: 593 RISTSGDVYSFGIVLLEMLT-GKRP 522 + +++ DV+S+GIV+ E+++ G+RP Sbjct: 812 KFTSASDVWSYGIVMWEVMSYGERP 836
>LCK_SAISC (Q95KR7) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) Length = 508 Score = 44.7 bits (104), Expect = 3e-04 Identities = 28/91 (30%), Positives = 45/91 (49%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 IH DL+ +NIL+ D + + DFG+AR+ D+ T+ G + G Sbjct: 360 IHRDLRAANILVSDTLSCKIADFGLARLIEDN-----EYTAREGAKFPIKWTAPEAINYG 414 Query: 593 RISTSGDVYSFGIVLLEMLTGKRPTDPMFTD 501 + DV+SFGI++ E++T R P T+ Sbjct: 415 TFTIKSDVWSFGILMTEIVTHGRIPYPGMTN 445
>MP2K1_RAT (Q01986) Dual specificity mitogen-activated protein kinase kinase 1| (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) Length = 392 Score = 44.7 bits (104), Expect = 3e-04 Identities = 29/97 (29%), Positives = 46/97 (47%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 I+H D+KPSNIL++ L DFG++ +DS + S +G R Sbjct: 185 IMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDS-----MANSFVGTR---SYMSPERLQG 236 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRPTDPMFTDGLDIV 486 S D++S G+ L+EM G+ P P L+++ Sbjct: 237 THYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELL 273
>MP2K1_RABIT (P29678) Dual specificity mitogen-activated protein kinase kinase 1| (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) Length = 392 Score = 44.7 bits (104), Expect = 3e-04 Identities = 29/97 (29%), Positives = 46/97 (47%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 I+H D+KPSNIL++ L DFG++ +DS + S +G R Sbjct: 185 IMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDS-----MANSFVGTR---SYMSPERLQG 236 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRPTDPMFTDGLDIV 486 S D++S G+ L+EM G+ P P L+++ Sbjct: 237 THYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELM 273
>MP2K1_MOUSE (P31938) Dual specificity mitogen-activated protein kinase kinase 1| (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) Length = 392 Score = 44.7 bits (104), Expect = 3e-04 Identities = 29/97 (29%), Positives = 46/97 (47%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 I+H D+KPSNIL++ L DFG++ +DS + S +G R Sbjct: 185 IMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDS-----MANSFVGTR---SYMSPERLQG 236 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRPTDPMFTDGLDIV 486 S D++S G+ L+EM G+ P P L+++ Sbjct: 237 THYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELL 273
>MP2K1_HUMAN (Q02750) Dual specificity mitogen-activated protein kinase kinase 1| (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) Length = 392 Score = 44.7 bits (104), Expect = 3e-04 Identities = 29/97 (29%), Positives = 46/97 (47%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 I+H D+KPSNIL++ L DFG++ +DS + S +G R Sbjct: 185 IMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDS-----MANSFVGTR---SYMSPERLQG 236 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRPTDPMFTDGLDIV 486 S D++S G+ L+EM G+ P P L+++ Sbjct: 237 THYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELM 273
>MOS_MSVMO (P00538) Serine/threonine-protein kinase transforming protein mos| (EC 2.7.11.1) Length = 374 Score = 44.7 bits (104), Expect = 3e-04 Identities = 28/85 (32%), Positives = 39/85 (45%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 I+H DLKP+NIL+ + V + DFG ++ D R AS G Sbjct: 225 ILHLDLKPANILISEQDVCKISDFGCSQKLQDLRGRQASPPHIGGTYTHQAPEILKGEIA 284 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRP 522 + D+YSFGI L +M T + P Sbjct: 285 ---TPKADIYSFGITLWQMTTREVP 306
>MP2K1_CRIGR (Q63980) Dual specificity mitogen-activated protein kinase kinase 1| (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) Length = 393 Score = 44.7 bits (104), Expect = 3e-04 Identities = 29/97 (29%), Positives = 46/97 (47%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 I+H D+KPSNIL++ L DFG++ +DS + S +G R Sbjct: 186 IMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDS-----MANSFVGTR---SYMSPERLQG 237 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRPTDPMFTDGLDIV 486 S D++S G+ L+EM G+ P P L+++ Sbjct: 238 THYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELL 274
>HCK_MACFA (Q95M30) Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK)| (Hemopoietic cell kinase) Length = 503 Score = 44.7 bits (104), Expect = 3e-04 Identities = 27/80 (33%), Positives = 42/80 (52%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 IH DL+ +NIL+ +V + DFG+ARI D+ T+ G + G Sbjct: 355 IHRDLRAANILVSASLVCKIADFGLARIIEDN-----EYTAREGAKFPIKWTAPEAINFG 409 Query: 593 RISTSGDVYSFGIVLLEMLT 534 + DV+SFGI+L+E++T Sbjct: 410 SSTIKSDVWSFGILLMEIVT 429
>MP2K1_SERCA (Q91447) Dual specificity mitogen-activated protein kinase kinase 1| (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) (Fragment) Length = 388 Score = 44.7 bits (104), Expect = 3e-04 Identities = 29/97 (29%), Positives = 47/97 (48%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 I+H D+KPSNIL++ L DFG++ +DS + S +G R Sbjct: 179 IMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDS-----MANSFVGTR---SYMSPERLQG 230 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRPTDPMFTDGLDIV 486 S D++S G+ L+EM G+ P P + L+++ Sbjct: 231 THYSVQSDIWSMGLSLVEMAIGRYPIPPPDSKELELM 267
>PKN1_CORGL (Q8NU98) Probable serine/threonine protein kinase pknB (EC| 2.7.11.1) Length = 646 Score = 44.7 bits (104), Expect = 3e-04 Identities = 27/85 (31%), Positives = 41/85 (48%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 IIH D+KP+NI++ + + DFGIAR DS +++ IG Sbjct: 132 IIHRDVKPANIMITNTGGVKVMDFGIARAVNDSTSAMTQTSAVIG---TAQYLSPEQARG 188 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRP 522 D+Y+ G V+ E++TGK P Sbjct: 189 KPADARSDIYATGCVMYELVTGKPP 213
>STK_HYDAT (P17713) Tyrosine-protein kinase STK (EC 2.7.10.2) (P57-STK)| Length = 509 Score = 44.7 bits (104), Expect = 3e-04 Identities = 28/95 (29%), Positives = 44/95 (46%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 IH DL NIL+ ++ + + DFG+AR+ D T+ G + Sbjct: 357 IHRDLAARNILVGENYICKVADFGLARLIEDD-----EYTAHEGAKFPIKWTAPEAALYN 411 Query: 593 RISTSGDVYSFGIVLLEMLTGKRPTDPMFTDGLDI 489 R + DV+SFGI++ E++T R P T+ I Sbjct: 412 RFTIKSDVWSFGILMAEIVTKGRIPYPGMTNAQTI 446
>PHKG2_MOUSE (Q9DB30) Phosphorylase b kinase gamma catalytic chain, testis/liver| isoform (EC 2.7.11.19) (PHK-gamma-T) (Phosphorylase kinase gamma subunit 2) Length = 406 Score = 44.3 bits (103), Expect = 4e-04 Identities = 26/85 (30%), Positives = 39/85 (45%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 I+H DLKP NILLDD+M L DFG + L++G + + G Sbjct: 149 IVHRDLKPENILLDDNMQIRLSDFGFS-CHLEAGEKLRELCGTPGYLAPEILKCSMDETH 207 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRP 522 D+++ G++L +L G P Sbjct: 208 PGYGKEVDLWACGVILFTLLAGSPP 232
>SSK22_YEAST (P25390) Serine/threonine-protein kinase SSK22 (EC 2.7.11.1) (MAP| kinase kinase kinase SSK22) (Suppressor of sensor kinase 22) Length = 1331 Score = 44.3 bits (103), Expect = 4e-04 Identities = 30/98 (30%), Positives = 43/98 (43%), Gaps = 13/98 (13%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPA--SSTSSIGVRXXXXXXXXXXX 603 ++H D+KP NILLD + + DFG AR + S R ++ GV Sbjct: 1154 VVHRDIKPENILLDFNGIIKYVDFGTARTVVGSRTRTVRNAAVQDFGVETKSLNEMMGTP 1213 Query: 602 XXGRIST-----------SGDVYSFGIVLLEMLTGKRP 522 T + DV++ G V+LEM TG+RP Sbjct: 1214 MYMAPETISGSAVKGKLGADDVWALGCVVLEMATGRRP 1251
>HTK7_HYDAT (Q25197) Putative insulin-like peptide receptor precursor (EC| 2.7.10.1) Length = 1477 Score = 44.3 bits (103), Expect = 4e-04 Identities = 25/80 (31%), Positives = 37/80 (46%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 +HCDL N ++ D +GDFG+AR + S + +R Sbjct: 1172 VHCDLAARNCMVASDFTVKIGDFGMARDIYERNYYRKDGKSLLPIRWMAPESLKDGI--- 1228 Query: 593 RISTSGDVYSFGIVLLEMLT 534 ST+ DV+SFG+VL E+ T Sbjct: 1229 -FSTASDVWSFGVVLWEICT 1247
>PHO85_KLULA (Q92241) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 304 Score = 44.3 bits (103), Expect = 4e-04 Identities = 33/95 (34%), Positives = 46/95 (48%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 I+H DLKP N+L+++ LGDFG+AR F P ++ SS V Sbjct: 129 ILHRDLKPQNLLINNRGQLKLGDFGLARAF----GIPVNTFSS-EVVTLWYRAPDVLMGS 183 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRPTDPMFTDGLD 492 TS D++S G +L EM+ GK P+F D Sbjct: 184 RNYCTSIDIWSCGCILAEMIMGK----PLFPGSND 214
>PKN2_CLOPE (Q8XJL8) Probable serine/threonine protein kinase CPE1738 (EC| 2.7.11.1) Length = 685 Score = 44.3 bits (103), Expect = 4e-04 Identities = 32/85 (37%), Positives = 44/85 (51%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 IIH D+KP NIL+ ++ V + DFGIA+ +DS + T+S+ Sbjct: 129 IIHRDVKPQNILVTEEGVVKVTDFGIAK-SMDSS--TIAHTNSVMGSAHYFSPEQAKGTY 185 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRP 522 T D+YS GIVL EM+TG P Sbjct: 186 TDYRT--DLYSLGIVLYEMVTGVVP 208
>CHK1_CAEBR (Q61RA2) Serine/threonine-protein kinase chk-1 (EC 2.7.11.1)| Length = 493 Score = 44.3 bits (103), Expect = 4e-04 Identities = 29/94 (30%), Positives = 41/94 (43%), Gaps = 7/94 (7%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 I+H D+KP N+LL V + DFG+A ++ + G R Sbjct: 146 IVHRDIKPENLLLTTSHVLKISDFGMATLYRNEGKE----------RLLDLSCGTIPYAA 195 Query: 596 GRISTSG-------DVYSFGIVLLEMLTGKRPTD 516 + G DV+S GIVL+ MLTG+ P D Sbjct: 196 PEVCAGGKYRGPPIDVWSSGIVLIAMLTGELPWD 229
>RIPK2_MOUSE (P58801) Receptor-interacting serine/threonine-protein kinase 2 (EC| 2.7.11.1) Length = 539 Score = 44.3 bits (103), Expect = 4e-04 Identities = 29/99 (29%), Positives = 49/99 (49%), Gaps = 2/99 (2%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIA--RIFLDSGPRPASSTSSIGVRXXXXXXXXXXX 603 ++H DLK NILLD++ + DFG++ R+ S R S G Sbjct: 142 LLHHDLKTQNILLDNEFHVKIADFGLSKWRMMSLSQSRSYKSAPEGGTIIYMPPENYEPG 201 Query: 602 XXGRISTSGDVYSFGIVLLEMLTGKRPTDPMFTDGLDIV 486 R S D+YS+ +++ E+L+ K+P + + T+ L I+ Sbjct: 202 QKSRASVKHDIYSYAVIMWEVLSRKQPFEEV-TNPLQIM 239
>KOIA_SCHPO (Q9Y7J6) Putative serine/threonine-protein kinase C1778.10c (EC| 2.7.11.1) Length = 550 Score = 44.3 bits (103), Expect = 4e-04 Identities = 28/89 (31%), Positives = 43/89 (48%), Gaps = 4/89 (4%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARI----FLDSGPRPASSTSSIGVRXXXXXXXXX 609 IIH DLKP NIL D +M + DFG A+I +++S +S +G Sbjct: 174 IIHRDLKPENILFDGNMHVKITDFGTAKILPPKYVNSPDYTTFPSSFVGTAEYVAPELLS 233 Query: 608 XXXXGRISTSGDVYSFGIVLLEMLTGKRP 522 +S S D+++F V+ +M+ G P Sbjct: 234 RQV---VSKSSDLWAFACVVYQMIVGSPP 259
>ERK1_CANAL (P28869) Extracellular signal-regulated kinase 1 (EC 2.7.11.24)| (ERK1) (MAP kinase 1) (MAPK 1) Length = 417 Score = 44.3 bits (103), Expect = 4e-04 Identities = 33/128 (25%), Positives = 57/128 (44%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 ++H DLKPSN+LL+ + + DFG+AR T + R Sbjct: 188 VLHRDLKPSNLLLNSNCDLKICDFGLARSIASQEDNYGFMTEYVATR--WYRAPEIMLTF 245 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRPTDPMFTDGLDIVNFVGSEFPHQIHEVIDIYLKGEC 417 +T+ DV+S G +L EML+G+ P+F G ++ +Q+ ++++ Sbjct: 246 QEYTTAIDVWSVGCILAEMLSGR----PLFP---------GRDYHNQLWLIMEVLGTPNM 292 Query: 416 EDSAEARS 393 ED +S Sbjct: 293 EDYYNIKS 300
>KS6A_CAEEL (Q21734) Putative ribosomal protein S6 kinase alpha (EC 2.7.11.1)| Length = 784 Score = 44.3 bits (103), Expect = 4e-04 Identities = 27/85 (31%), Positives = 42/85 (49%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 I++ DLKP NILLD D + DFG+++ +DS + S ++ Sbjct: 225 IVYRDLKPENILLDADGHIKVTDFGLSKEAIDSEKKTYSFCGTVEYMAPEVINRRGH--- 281 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRP 522 S + D +S G+++ EMLTG P Sbjct: 282 ---SMAADFWSLGVLMFEMLTGHLP 303
>LYN_RAT (Q07014) Tyrosine-protein kinase Lyn (EC 2.7.10.2)| Length = 511 Score = 44.3 bits (103), Expect = 4e-04 Identities = 27/85 (31%), Positives = 45/85 (52%), Gaps = 1/85 (1%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 IH DL+ +N+L+ + ++ + DFG+AR+ D+ T+ G + G Sbjct: 363 IHRDLRAANVLVSESLMCKIADFGLARVIEDN-----EYTAREGAKFPIKWTAPEAINFG 417 Query: 593 RISTSGDVYSFGIVLLEMLT-GKRP 522 + DV+SFGI+L E++T GK P Sbjct: 418 CFTIKSDVWSFGILLYEIVTYGKIP 442
>LYN_MOUSE (P25911) Tyrosine-protein kinase Lyn (EC 2.7.10.2)| Length = 511 Score = 44.3 bits (103), Expect = 4e-04 Identities = 27/85 (31%), Positives = 45/85 (52%), Gaps = 1/85 (1%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 IH DL+ +N+L+ + ++ + DFG+AR+ D+ T+ G + G Sbjct: 363 IHRDLRAANVLVSESLMCKIADFGLARVIEDN-----EYTAREGAKFPIKWTAPEAINFG 417 Query: 593 RISTSGDVYSFGIVLLEMLT-GKRP 522 + DV+SFGI+L E++T GK P Sbjct: 418 CFTIKSDVWSFGILLYEIVTYGKIP 442
>LYN_HUMAN (P07948) Tyrosine-protein kinase Lyn (EC 2.7.10.2)| Length = 511 Score = 44.3 bits (103), Expect = 4e-04 Identities = 27/85 (31%), Positives = 45/85 (52%), Gaps = 1/85 (1%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXXG 594 IH DL+ +N+L+ + ++ + DFG+AR+ D+ T+ G + G Sbjct: 363 IHRDLRAANVLVSESLMCKIADFGLARVIEDN-----EYTAREGAKFPIKWTAPEAINFG 417 Query: 593 RISTSGDVYSFGIVLLEMLT-GKRP 522 + DV+SFGI+L E++T GK P Sbjct: 418 CFTIKSDVWSFGILLYEIVTYGKIP 442
>KS6A1_RAT (Q63531) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 735 Score = 44.3 bits (103), Expect = 4e-04 Identities = 27/85 (31%), Positives = 43/85 (50%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 II+ DLKP NILLD++ L DFG+++ +D + S ++ Sbjct: 183 IIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQGH--- 239 Query: 596 GRISTSGDVYSFGIVLLEMLTGKRP 522 + S D +S+G+++ EMLTG P Sbjct: 240 ---THSADWWSYGVLMFEMLTGSLP 261
>RIPK2_HUMAN (O43353) Receptor-interacting serine/threonine-protein kinase 2 (EC| 2.7.11.1) (RIP-like-interacting CLARP kinase) (Receptor-interacting protein 2) (RIP-2) (CARD-containing interleukin-1 beta-converting enzyme-associated kinase) (CARD-containi Length = 540 Score = 44.3 bits (103), Expect = 4e-04 Identities = 32/112 (28%), Positives = 53/112 (47%), Gaps = 2/112 (1%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIA--RIFLDSGPRPASSTSSIGVRXXXXXXXXXXX 603 ++H DLK NILLD++ + DFG++ R+ S R + S G Sbjct: 142 LLHHDLKTQNILLDNEFHVKIADFGLSKWRMMSLSQSRSSKSAPEGGTIIYMPPENYEPG 201 Query: 602 XXGRISTSGDVYSFGIVLLEMLTGKRPTDPMFTDGLDIVNFVGSEFPHQIHE 447 R S D+YS+ ++ E+L+ K+P + + T+ L I+ V I+E Sbjct: 202 QKSRASIKHDIYSYAVITWEVLSRKQPFEDV-TNPLQIMYSVSQGHRPVINE 252
>MOS_RAT (P00539) Proto-oncogene serine/threonine-protein kinase mos (EC| 2.7.11.1) (c-mos) (Oocyte maturation factor mos) Length = 339 Score = 44.3 bits (103), Expect = 4e-04 Identities = 32/86 (37%), Positives = 43/86 (50%), Gaps = 1/86 (1%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 I+H DLKP+NIL+ + V + DFG ++ D RP S IG Sbjct: 192 ILHLDLKPANILISEKDVCKISDFGCSQKLQDLRCRP--SLHHIG---GTYTHQAPELLK 246 Query: 596 GRIST-SGDVYSFGIVLLEMLTGKRP 522 G I+T D+YSFGI L +M T + P Sbjct: 247 GEIATPKADIYSFGITLWQMTTREVP 272
>MIL_AVIMH (P00531) Serine/threonine-protein kinase transforming protein mil| (EC 2.7.11.1) Length = 380 Score = 44.3 bits (103), Expect = 4e-04 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 1/86 (1%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLD-SGPRPASSTSSIGVRXXXXXXXXXXXX 600 IIH D+K +NI L + +GDFG+A + SG + + G Sbjct: 197 IIHRDMKSNNIFLHGGLTVKIGDFGLATVKSRWSGSQQVEQPT--GSILWMAPEVIRMQD 254 Query: 599 XGRISTSGDVYSFGIVLLEMLTGKRP 522 S DVYS+GIVL E++TG+ P Sbjct: 255 SNPFSFQSDVYSYGIVLYELMTGELP 280
>EPA4A_BRARE (O13148) Ephrin type-A receptor 4a (EC 2.7.10.1) (Tyrosine-protein| kinase receptor ZEK2) (EPH-like kinase 2) (Fragment) Length = 292 Score = 43.9 bits (102), Expect = 6e-04 Identities = 27/92 (29%), Positives = 50/92 (54%), Gaps = 8/92 (8%) Frame = -3 Query: 773 IHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSI-------GVRXXXXXXX 615 +H DL NIL++ ++V + DFG++R+ L+ P A +T I G + Sbjct: 117 VHRDLAARNILVNSNLVCKVSDFGMSRV-LEEDPDAAYTTREITGTYQSQGGKIPIRWTA 175 Query: 614 XXXXXXGRISTSGDVYSFGIVLLEMLT-GKRP 522 + +++ DV+S+GIV+ E+++ G+RP Sbjct: 176 PEAITYRKFTSASDVWSYGIVMWEVMSYGERP 207
>PKSC_STRCO (Q9S2C0) Serine/threonine protein kinase pksC (EC 2.7.11.1)| Length = 556 Score = 43.9 bits (102), Expect = 6e-04 Identities = 28/88 (31%), Positives = 46/88 (52%), Gaps = 1/88 (1%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 ++H D+KP N+++ V + DFGIAR + SG +S + G+ Sbjct: 147 LVHRDIKPGNVMMTKRGVVKVMDFGIARA-MQSG---VTSMTQTGMVVGTPQYLSPEQAL 202 Query: 596 GR-ISTSGDVYSFGIVLLEMLTGKRPTD 516 GR + D+YS GI+L +++TG+ P D Sbjct: 203 GRGVDARSDLYSVGIMLFQLVTGRLPFD 230
>MP2K7_HUMAN (O14733) Dual specificity mitogen-activated protein kinase kinase 7| (EC 2.7.12.2) (MAP kinase kinase 7) (MAPKK 7) (MAPK/ERK kinase 7) (JNK-activating kinase 2) (c-Jun N-terminal kinase kinase 2) (JNK kinase 2) (JNKK 2) Length = 419 Score = 43.9 bits (102), Expect = 6e-04 Identities = 33/94 (35%), Positives = 44/94 (46%), Gaps = 2/94 (2%) Frame = -3 Query: 776 IIHCDLKPSNILLDDDMVAHLGDFGIARIFLDSGPRPASSTSSIGVRXXXXXXXXXXXXX 597 +IH D+KPSNILLD+ L DFGI+ +DS + T S G Sbjct: 239 VIHRDVKPSNILLDERGQIKLCDFGISGRLVDS----KAKTRSAGCAAYMAPERIDPPDP 294 Query: 596 GR--ISTSGDVYSFGIVLLEMLTGKRPTDPMFTD 501 + DV+S GI L+E+ TG+ P TD Sbjct: 295 TKPDYDIRADVWSLGISLVELATGQFPYKNCKTD 328 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 118,633,057 Number of Sequences: 219361 Number of extensions: 2654956 Number of successful extensions: 9728 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 8529 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 9153 length of database: 80,573,946 effective HSP length: 110 effective length of database: 56,444,236 effective search space used: 8353746928 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
