ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
menu 
| Clone Name | rbags31m13 |
|---|---|
| Clone Library Name | barley_pub |
>TMKL1_ARATH (P33543) Putative kinase-like protein TMKL1 precursor| Length = 674 Score = 110 bits (275), Expect = 4e-24 Identities = 62/154 (40%), Positives = 97/154 (62%), Gaps = 7/154 (4%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATL----VGSSSSGPSRATGYRAPEVTDPRRVSQKA 515 HGNI+S N+L+ + AR+++ GL + V +++ GY+APE+ ++ + ++ Sbjct: 498 HGNIRSKNVLVDDFFFARLTEFGLDKIMVQAVADEIVSQAKSDGYKAPELHKMKKCNPRS 557 Query: 514 DVFSFGVLLLELLTGKAPSQSALN-DEGVDLPRWVQSVVRSEWTSEVFDMELLRNQSS-- 344 DV++FG+LLLE+L GK P +S N +E VDLP V++ V E T EVFD+E ++ S Sbjct: 558 DVYAFGILLLEILMGKKPGKSGRNGNEFVDLPSLVKAAVLEETTMEVFDLEAMKGIRSPM 617 Query: 343 EEQMVQLLQLAIDCVAQVPDARPTMSHVVVRIEE 242 EE +V L+LA+ C A V RP+M VV ++EE Sbjct: 618 EEGLVHALKLAMGCCAPVTTVRPSMEEVVKQLEE 651
>BRL1_ARATH (Q9ZWC8) Serine/threonine-protein kinase BRI1-like 1 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 1) Length = 1166 Score = 100 bits (250), Expect = 3e-21 Identities = 58/162 (35%), Positives = 92/162 (56%), Gaps = 5/162 (3%) Frame = -1 Query: 706 HSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRAT-----GYRAPEVT 542 HS H ++KSSN+LL + ++ARVSD G+A LV + + S +T GY PE Sbjct: 977 HSCIPHIIHRDMKSSNVLLDEDFEARVSDFGMARLVSALDTHLSVSTLAGTPGYVPPEYY 1036 Query: 541 DPRRVSQKADVFSFGVLLLELLTGKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFDMEL 362 R + K DV+S+GV+LLELL+GK P E +L W + + R + +E+ D EL Sbjct: 1037 QSFRCTAKGDVYSYGVILLELLSGKKPIDPGEFGEDNNLVGWAKQLYREKRGAEILDPEL 1096 Query: 361 LRNQSSEEQMVQLLQLAIDCVAQVPDARPTMSHVVVRIEEIK 236 + ++S + ++ L++A C+ P RPTM ++ +E+K Sbjct: 1097 VTDKSGDVELFHYLKIASQCLDDRPFKRPTMIQLMAMFKEMK 1138
>BRL3_ARATH (Q9LJF3) Serine/threonine-protein kinase BRI1-like 3 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 3) Length = 1164 Score = 99.4 bits (246), Expect = 1e-20 Identities = 58/161 (36%), Positives = 91/161 (56%), Gaps = 5/161 (3%) Frame = -1 Query: 706 HSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRAT-----GYRAPEVT 542 HS H ++KSSN+LL + + ARVSD G+A LV + + S +T GY PE Sbjct: 975 HSCIPHIIHRDMKSSNVLLDQDFVARVSDFGMARLVSALDTHLSVSTLAGTPGYVPPEYY 1034 Query: 541 DPRRVSQKADVFSFGVLLLELLTGKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFDMEL 362 R + K DV+S+GV+LLELL+GK P E +L W + + R + +E+ D EL Sbjct: 1035 QSFRCTAKGDVYSYGVILLELLSGKKPIDPEEFGEDNNLVGWAKQLYREKRGAEILDPEL 1094 Query: 361 LRNQSSEEQMVQLLQLAIDCVAQVPDARPTMSHVVVRIEEI 239 + ++S + +++ L++A C+ P RPTM V+ +E+ Sbjct: 1095 VTDKSGDVELLHYLKIASQCLDDRPFKRPTMIQVMTMFKEL 1135
>RLK5_ARATH (P47735) Receptor-like protein kinase 5 precursor (EC 2.7.11.1)| Length = 999 Score = 96.7 bits (239), Expect = 6e-20 Identities = 58/156 (37%), Positives = 95/156 (60%), Gaps = 8/156 (5%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSS--------SGPSRATGYRAPEVTDPRRV 527 H ++KSSNILL Y A+V+D G+A VG S SG + + GY APE RV Sbjct: 817 HRDVKSSNILLDSDYGAKVADFGIAK-VGQMSGSKTPEAMSGIAGSCGYIAPEYVYTLRV 875 Query: 526 SQKADVFSFGVLLLELLTGKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFDMELLRNQS 347 ++K+D++SFGV+LLEL+TGK P+ S L D+ D+ +WV + + V D +L + Sbjct: 876 NEKSDIYSFGVVLLELVTGKQPTDSELGDK--DMAKWVCTALDKCGLEPVIDPKL--DLK 931 Query: 346 SEEQMVQLLQLAIDCVAQVPDARPTMSHVVVRIEEI 239 +E++ +++ + + C + +P RP+M VV+ ++E+ Sbjct: 932 FKEEISKVIHIGLLCTSPLPLNRPSMRKVVIMLQEV 967
>BRI1_LYCPE (Q8L899) Systemin receptor SR160 precursor (EC 2.7.11.1)| (Brassinosteroid LRR receptor kinase) Length = 1207 Score = 94.0 bits (232), Expect = 4e-19 Identities = 64/163 (39%), Positives = 96/163 (58%), Gaps = 6/163 (3%) Frame = -1 Query: 706 HSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRAT-----GYRAPEVT 542 H+ H ++KSSN+LL + +ARVSD G+A L+ + + S +T GY PE Sbjct: 1004 HNCIPHIIHRDMKSSNVLLDENLEARVSDFGMARLMSAMDTHLSVSTLAGTPGYVPPEYY 1063 Query: 541 DPRRVSQKADVFSFGVLLLELLTGKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFDMEL 362 R S K DV+S+GV+LLELLTGK P+ SA + +L WV+ + + T +VFD EL Sbjct: 1064 QSFRCSTKGDVYSYGVVLLELLTGKQPTDSADFGDN-NLVGWVKLHAKGKIT-DVFDREL 1121 Query: 361 LRNQSS-EEQMVQLLQLAIDCVAQVPDARPTMSHVVVRIEEIK 236 L+ +S E +++Q L++A C+ RPTM V+ +EI+ Sbjct: 1122 LKEDASIEIELLQHLKVACACLDDRHWKRPTMIQVMAMFKEIQ 1164
>BRI1_LYCES (Q8GUQ5) Brassinosteroid LRR receptor kinase precursor (EC 2.7.11.1)| (tBRI1) (Altered brassinolide sensitivity 1) (Systemin receptor SR160) Length = 1207 Score = 94.0 bits (232), Expect = 4e-19 Identities = 64/163 (39%), Positives = 96/163 (58%), Gaps = 6/163 (3%) Frame = -1 Query: 706 HSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRAT-----GYRAPEVT 542 H+ H ++KSSN+LL + +ARVSD G+A L+ + + S +T GY PE Sbjct: 1004 HNCIPHIIHRDMKSSNVLLDENLEARVSDFGMARLMSAMDTHLSVSTLAGTPGYVPPEYY 1063 Query: 541 DPRRVSQKADVFSFGVLLLELLTGKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFDMEL 362 R S K DV+S+GV+LLELLTGK P+ SA + +L WV+ + + T +VFD EL Sbjct: 1064 QSFRCSTKGDVYSYGVVLLELLTGKQPTDSADFGDN-NLVGWVKLHAKGKIT-DVFDREL 1121 Query: 361 LRNQSS-EEQMVQLLQLAIDCVAQVPDARPTMSHVVVRIEEIK 236 L+ +S E +++Q L++A C+ RPTM V+ +EI+ Sbjct: 1122 LKEDASIEIELLQHLKVACACLDDRHWKRPTMIQVMAMFKEIQ 1164
>BRI1_ARATH (O22476) BRASSINOSTEROID INSENSITIVE 1 precursor (EC 2.7.11.1)| (AtBRI1) (Brassinosteroid LRR receptor kinase) Length = 1196 Score = 93.2 bits (230), Expect = 7e-19 Identities = 62/163 (38%), Positives = 95/163 (58%), Gaps = 6/163 (3%) Frame = -1 Query: 706 HSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRAT-----GYRAPEVT 542 H+ S H ++KSSN+LL + +ARVSD G+A L+ + + S +T GY PE Sbjct: 999 HNCSPHIIHRDMKSSNVLLDENLEARVSDFGMARLMSAMDTHLSVSTLAGTPGYVPPEYY 1058 Query: 541 DPRRVSQKADVFSFGVLLLELLTGKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFDMEL 362 R S K DV+S+GV+LLELLTGK P+ S + +L WV+ + S+VFD EL Sbjct: 1059 QSFRCSTKGDVYSYGVVLLELLTGKRPTDSPDFGDN-NLVGWVKQHAKLR-ISDVFDPEL 1116 Query: 361 LRNQSS-EEQMVQLLQLAIDCVAQVPDARPTMSHVVVRIEEIK 236 ++ + E +++Q L++A+ C+ RPTM V+ +EI+ Sbjct: 1117 MKEDPALEIELLQHLKVAVACLDDRAWRRPTMVQVMAMFKEIQ 1159
>EXS_ARATH (Q9LYN8) Leucine-rich repeat receptor protein kinase EXS precursor| (EC 2.7.11.1) (Extra sporogenous cells protein) (EXCESS MICROSPOROCYTES1 protein) Length = 1192 Score = 90.5 bits (223), Expect = 5e-18 Identities = 57/153 (37%), Positives = 86/153 (56%), Gaps = 5/153 (3%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRAT----GYRAPEVTDPRRVSQKA 515 H +IK+SNILL ++ +V+D GLA L+ + S S GY PE R + K Sbjct: 1041 HRDIKASNILLDGDFEPKVADFGLARLISACESHVSTVIAGTFGYIPPEYGQSARATTKG 1100 Query: 514 DVFSFGVLLLELLTGKAPSQSALND-EGVDLPRWVQSVVRSEWTSEVFDMELLRNQSSEE 338 DV+SFGV+LLEL+TGK P+ + EG +L W + +V D LL + + + Sbjct: 1101 DVYSFGVILLELVTGKEPTGPDFKESEGGNLVGWAIQKINQGKAVDVID-PLLVSVALKN 1159 Query: 337 QMVQLLQLAIDCVAQVPDARPTMSHVVVRIEEI 239 ++LLQ+A+ C+A+ P RP M V+ ++EI Sbjct: 1160 SQLRLLQIAMLCLAETPAKRPNMLDVLKALKEI 1192
>BAK1_ARATH (Q94F62) BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1| precursor (EC 2.7.11.1) (BRI1-associated receptor kinase 1) (Somatic embryogenesis receptor-like kinase 3) Length = 615 Score = 89.7 bits (221), Expect = 8e-18 Identities = 56/152 (36%), Positives = 87/152 (57%), Gaps = 6/152 (3%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRAT----GYRAPEVTDPRRVSQKA 515 H ++K++NILL + ++A V D GLA L+ + + A G+ APE + S+K Sbjct: 414 HRDVKAANILLDEEFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKT 473 Query: 514 DVFSFGVLLLELLTGKAPSQSA--LNDEGVDLPRWVQSVVRSEWTSEVFDMELLRNQSSE 341 DVF +GV+LLEL+TG+ A ND+ V L WV+ +++ + + D++L N E Sbjct: 474 DVFGYGVMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKLEALVDVDLQGNYKDE 533 Query: 340 EQMVQLLQLAIDCVAQVPDARPTMSHVVVRIE 245 E + QL+Q+A+ C P RP MS VV +E Sbjct: 534 E-VEQLIQVALLCTQSSPMERPKMSEVVRMLE 564
>BRL2_ARATH (Q9ZPS9) Serine/threonine-protein kinase BRI1-like 2 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 2) (Protein VASCULAR HIGHWAY 1) Length = 1143 Score = 88.6 bits (218), Expect = 2e-17 Identities = 58/176 (32%), Positives = 91/176 (51%), Gaps = 19/176 (10%) Frame = -1 Query: 706 HSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRAT-----GYRAPEVT 542 H+ H ++KSSN+LL + +ARVSD G+A L+ + + S +T GY PE Sbjct: 956 HNCIPHIIHRDMKSSNVLLDQDMEARVSDFGMARLISALDTHLSVSTLAGTPGYVPPEYY 1015 Query: 541 DPRRVSQKADVFSFGVLLLELLTGKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFDMEL 362 R + K DV+S GV++LE+L+GK P+ + +L W + R EV D +L Sbjct: 1016 QSFRCTAKGDVYSIGVVMLEILSGKRPTDKEEFGD-TNLVGWSKMKAREGKHMEVIDEDL 1074 Query: 361 LRNQSSE--------------EQMVQLLQLAIDCVAQVPDARPTMSHVVVRIEEIK 236 L+ SSE ++M++ L++A+ CV P RP M VV + E++ Sbjct: 1075 LKEGSSESLNEKEGFEGGVIVKEMLRYLEIALRCVDDFPSKRPNMLQVVASLRELR 1130
>PSKR_DAUCA (Q8LPB4) Phytosulfokine receptor precursor (EC 2.7.11.1)| (Phytosulfokine LRR receptor kinase) Length = 1021 Score = 88.6 bits (218), Expect = 2e-17 Identities = 58/163 (35%), Positives = 85/163 (52%), Gaps = 5/163 (3%) Frame = -1 Query: 712 YIH-STSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSR----ATGYRAPE 548 Y+H S H +IKSSNILLS + A ++D GLA L+ + + GY PE Sbjct: 856 YLHQSCEPHILHRDIKSSNILLSDTFVAHLADFGLARLILPYDTHVTTDLVGTLGYIPPE 915 Query: 547 VTDPRRVSQKADVFSFGVLLLELLTGKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFDM 368 + K DV+SFGV+LLELLTG+ P DL WV + + SE+FD Sbjct: 916 YGQASVATYKGDVYSFGVVLLELLTGRRPMDVCKPRGSRDLISWVLQMKTEKRESEIFD- 974 Query: 367 ELLRNQSSEEQMVQLLQLAIDCVAQVPDARPTMSHVVVRIEEI 239 + ++ E+M+ +L++A C+ + P RPT +V +E I Sbjct: 975 PFIYDKDHAEEMLLVLEIACRCLGENPKTRPTTQQLVSWLENI 1017
>PSKR_ARATH (Q9ZVR7) Putative phytosulfokine receptor precursor (EC 2.7.11.1)| (Phytosulfokine LRR receptor kinase) Length = 1008 Score = 86.7 bits (213), Expect = 7e-17 Identities = 53/152 (34%), Positives = 84/152 (55%), Gaps = 4/152 (2%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSR----ATGYRAPEVTDPRRVSQKA 515 H +IKSSNILL + + + ++D GLA L+ + S GY PE + K Sbjct: 858 HRDIKSSNILLDENFNSHLADFGLARLMSPYETHVSTDLVGTLGYIPPEYGQASVATYKG 917 Query: 514 DVFSFGVLLLELLTGKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFDMELLRNQSSEEQ 335 DV+SFGV+LLELLT K P DL WV + SEVFD L+ ++ ++++ Sbjct: 918 DVYSFGVVLLELLTDKRPVDMCKPKGCRDLISWVVKMKHESRASEVFD-PLIYSKENDKE 976 Query: 334 MVQLLQLAIDCVAQVPDARPTMSHVVVRIEEI 239 M ++L++A C+++ P RPT +V ++++ Sbjct: 977 MFRVLEIACLCLSENPKQRPTTQQLVSWLDDV 1008
>CLV1_ARATH (Q9SYQ8) Receptor protein kinase CLAVATA1 precursor (EC 2.7.11.1)| Length = 980 Score = 82.0 bits (201), Expect = 2e-15 Identities = 57/160 (35%), Positives = 87/160 (54%), Gaps = 10/160 (6%) Frame = -1 Query: 706 HSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLV--GSSS---SGPSRATGYRAPEVT 542 H S H ++KS+NILL ++A V+D GLA + G++S S + + GY APE Sbjct: 807 HDCSPLILHRDVKSNNILLDSDFEAHVADFGLAKFLVDGAASECMSSIAGSYGYIAPEYA 866 Query: 541 DPRRVSQKADVFSFGVLLLELLTGKAPSQSALNDEGVDLPRWVQSVVR-----SEWTSEV 377 +V +K+DV+SFGV+LLEL+ GK P EGVD+ RWV++ S+ V Sbjct: 867 YTLKVDEKSDVYSFGVVLLELIAGKKPVGEF--GEGVDIVRWVRNTEEEITQPSDAAIVV 924 Query: 376 FDMELLRNQSSEEQMVQLLQLAIDCVAQVPDARPTMSHVV 257 ++ ++ + ++A+ CV + ARPTM VV Sbjct: 925 AIVDPRLTGYPLTSVIHVFKIAMMCVEEEAAARPTMREVV 964
>TMK1_ARATH (P43298) Putative receptor protein kinase TMK1 precursor (EC| 2.7.11.1) Length = 942 Score = 81.3 bits (199), Expect = 3e-15 Identities = 53/160 (33%), Positives = 84/160 (52%), Gaps = 7/160 (4%) Frame = -1 Query: 715 EYIHSTS-SSTSHGNIKSSNILLSKAYQARVSDNGLATLV----GSSSSGPSRATGYRAP 551 EY+H + S H ++K SNILL +A+V+D GL L GS + + GY AP Sbjct: 703 EYLHGLAHQSFIHRDLKPSNILLGDDMRAKVADFGLVRLAPEGKGSIETRIAGTFGYLAP 762 Query: 550 EVTDPRRVSQKADVFSFGVLLLELLTGKAPSQSALNDEGVDLPRWVQSVVRSEWTS--EV 377 E RV+ K DV+SFGV+L+EL+TG+ + +E + L W + + ++ S + Sbjct: 763 EYAVTGRVTTKVDVYSFGVILMELITGRKSLDESQPEESIHLVSWFKRMYINKEASFKKA 822 Query: 376 FDMELLRNQSSEEQMVQLLQLAIDCVAQVPDARPTMSHVV 257 D + ++ + + + +LA C A+ P RP M H V Sbjct: 823 IDTTIDLDEETLASVHTVAELAGHCCAREPYQRPDMGHAV 862
>RPK1_IPONI (P93194) Receptor-like protein kinase precursor (EC 2.7.11.1)| Length = 1109 Score = 80.1 bits (196), Expect = 6e-15 Identities = 60/169 (35%), Positives = 88/169 (52%), Gaps = 14/169 (8%) Frame = -1 Query: 712 YIH-STSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSG-PSRAT----GYRAP 551 Y+H + H +IK NILL + +SD G+A L+ S++ PS GY AP Sbjct: 929 YLHFDCDPAIVHRDIKPMNILLDSDLEPHISDFGIAKLLDQSATSIPSNTVQGTIGYMAP 988 Query: 550 EVTDPRRVSQKADVFSFGVLLLELLTGKAPSQSALNDEGVDLPRWVQSVVRSEWT----- 386 E S+++DV+S+GV+LLEL+T K + N E D+ WV+SV WT Sbjct: 989 ENAFTTVKSRESDVYSYGVVLLELITRKKALDPSFNGE-TDIVGWVRSV----WTQTGEI 1043 Query: 385 SEVFDMELLR---NQSSEEQMVQLLQLAIDCVAQVPDARPTMSHVVVRI 248 ++ D LL + S EQ+ + L LA+ C + D RPTM VV ++ Sbjct: 1044 QKIVDPSLLDELIDSSVMEQVTEALSLALRCAEKEVDKRPTMRDVVKQL 1092
>APK1A_ARATH (Q06548) Protein kinase APK1A, chloroplast precursor (EC 2.7.11.1)| Length = 410 Score = 79.7 bits (195), Expect = 8e-15 Identities = 55/165 (33%), Positives = 86/165 (52%), Gaps = 6/165 (3%) Frame = -1 Query: 712 YIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLAT--LVGSSSSGPSRATG---YRAPE 548 ++HS+ + + + K+SNILL Y A++SD GLA +G S +R G Y APE Sbjct: 191 FLHSSETRVIYRDFKTSNILLDSEYNAKLSDFGLAKDGPIGDKSHVSTRVMGTHGYAAPE 250 Query: 547 VTDPRRVSQKADVFSFGVLLLELLTGKAPSQSALNDEGVDLPRWVQS-VVRSEWTSEVFD 371 ++ K+DV+SFGV+LLELL+G+ +L W + +V V D Sbjct: 251 YLATGHLTTKSDVYSFGVVLLELLSGRRAVDKNRPSGERNLVEWAKPYLVNKRKIFRVID 310 Query: 370 MELLRNQSSEEQMVQLLQLAIDCVAQVPDARPTMSHVVVRIEEIK 236 L++Q S E+ ++ L++ C+ RP MS VV +E I+ Sbjct: 311 -NRLQDQYSMEEACKVATLSLRCLTTEIKLRPNMSEVVSHLEHIQ 354
>SIRK_ARATH (O64483) Senescence-induced receptor-like serine/threonine-protein| kinase precursor (FLG22-induced receptor-like kinase 1) Length = 876 Score = 78.2 bits (191), Expect = 2e-14 Identities = 50/165 (30%), Positives = 93/165 (56%), Gaps = 6/165 (3%) Frame = -1 Query: 715 EYIHS-TSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGP-----SRATGYRA 554 EY+H+ H ++K +NILL++ QA+++D GL+ SG + + GY Sbjct: 683 EYLHNGCKPPIVHRDVKPTNILLNEKLQAKMADFGLSRSFSVEGSGQISTVVAGSIGYLD 742 Query: 553 PEVTDPRRVSQKADVFSFGVLLLELLTGKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVF 374 PE R++++K+DV+S GV+LLE++TG+ P+ ++ E V + V+S++ + + Sbjct: 743 PEYYSTRQMNEKSDVYSLGVVLLEVITGQ-PAIASSKTEKVHISDHVRSILANGDIRGIV 801 Query: 373 DMELLRNQSSEEQMVQLLQLAIDCVAQVPDARPTMSHVVVRIEEI 239 D + LR + ++ ++A+ C RPTMS VV+ +++I Sbjct: 802 D-QRLRERYDVGSAWKMSEIALACTEHTSAQRPTMSQVVMELKQI 845
>NAK_ARATH (P43293) Probable serine/threonine-protein kinase NAK (EC 2.7.11.1)| Length = 389 Score = 77.8 bits (190), Expect = 3e-14 Identities = 52/163 (31%), Positives = 87/163 (53%), Gaps = 5/163 (3%) Frame = -1 Query: 712 YIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLAT--LVGSSSSGPSRATG---YRAPE 548 ++H+ + + K+SNILL Y A++SD GLA +G +S +R G Y APE Sbjct: 191 FLHNAQPQVIYRDFKASNILLDSNYNAKLSDFGLARDGPMGDNSHVSTRVMGTQGYAAPE 250 Query: 547 VTDPRRVSQKADVFSFGVLLLELLTGKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFDM 368 +S K+DV+SFGV+LLELL+G+ +L W + + ++ Sbjct: 251 YLATGHLSVKSDVYSFGVVLLELLSGRRAIDKNQPVGEHNLVDWARPYLTNKRRLLRVMD 310 Query: 367 ELLRNQSSEEQMVQLLQLAIDCVAQVPDARPTMSHVVVRIEEI 239 L+ Q S + +++ LA+DC++ +RPTM+ +V +EE+ Sbjct: 311 PRLQGQYSLTRALKIAVLALDCISIDAKSRPTMNEIVKTMEEL 353
>RLCK7_ARATH (Q9LQQ8) Probable serine/threonine-protein kinase RLCKVII (EC| 2.7.11.1) Length = 423 Score = 75.9 bits (185), Expect = 1e-13 Identities = 51/163 (31%), Positives = 84/163 (51%), Gaps = 7/163 (4%) Frame = -1 Query: 715 EYIHSTSSS-TSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRAT------GYR 557 EY+H + + ++K SNILL + YQ ++SD GLA VG S +T GY Sbjct: 216 EYLHDRMTPPVIYRDLKCSNILLGEDYQPKLSDFGLAK-VGPSGDKTHVSTRVMGTYGYC 274 Query: 556 APEVTDPRRVSQKADVFSFGVLLLELLTGKAPSQSALNDEGVDLPRWVQSVVRSEWTSEV 377 AP+ +++ K+D++SFGV+LLEL+TG+ + + +L W + + + Sbjct: 275 APDYAMTGQLTFKSDIYSFGVVLLELITGRKAIDNTKTRKDQNLVGWARPLFKDRRNFPK 334 Query: 376 FDMELLRNQSSEEQMVQLLQLAIDCVAQVPDARPTMSHVVVRI 248 LL+ Q + Q L ++ CV + P RP +S VV+ + Sbjct: 335 MVDPLLQGQYPVRGLYQALAISAMCVQEQPTMRPVVSDVVLAL 377
>APK1B_ARATH (P46573) Protein kinase APK1B, chloroplast precursor (EC 2.7.11.1)| Length = 412 Score = 74.3 bits (181), Expect = 3e-13 Identities = 50/164 (30%), Positives = 84/164 (51%), Gaps = 5/164 (3%) Frame = -1 Query: 712 YIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLAT--LVGSSSSGPSRATG---YRAPE 548 ++H+ +S + + K+SNILL Y A++SD GLA G S +R G Y APE Sbjct: 192 FLHNAETSVIYRDFKTSNILLDSEYNAKLSDFGLAKDGPTGDKSHVSTRIMGTYGYAAPE 251 Query: 547 VTDPRRVSQKADVFSFGVLLLELLTGKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFDM 368 ++ K+DV+S+GV+LLE+L+G+ L W + ++ ++ Sbjct: 252 YLATGHLTTKSDVYSYGVVLLEVLSGRRAVDKNRPPGEQKLVEWARPLLANKRKLFRVID 311 Query: 367 ELLRNQSSEEQMVQLLQLAIDCVAQVPDARPTMSHVVVRIEEIK 236 L++Q S E+ ++ LA+ C+ RP M+ VV +E I+ Sbjct: 312 NRLQDQYSMEEACKVATLALRCLTFEIKLRPNMNEVVSHLEHIQ 355
>NORK_MEDTR (Q8L4H4) Nodulation receptor kinase precursor (EC 2.7.11.1) (Does not| make infections protein 2) (Symbiosis receptor-like kinase) (MtSYMRK) Length = 925 Score = 73.9 bits (180), Expect = 4e-13 Identities = 50/163 (30%), Positives = 86/163 (52%), Gaps = 6/163 (3%) Frame = -1 Query: 712 YIHS-TSSSTSHGNIKSSNILLSKAYQARVSDNGLATLV----GSSSSGPSRAT-GYRAP 551 Y+H+ S H ++KSSNILL ++ A+V+D G + S S R T GY P Sbjct: 709 YLHTFPGRSVIHRDVKSSNILLDQSMCAKVADFGFSKYAPQEGDSYVSLEVRGTAGYLDP 768 Query: 550 EVTDPRRVSQKADVFSFGVLLLELLTGKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFD 371 E +++S+K+DVFSFGV+LLE+++G+ P L W + +R+ E+ D Sbjct: 769 EYYKTQQLSEKSDVFSFGVVLLEIVSGREPLNIKRPRIEWSLVEWAKPYIRASKVDEIVD 828 Query: 370 MELLRNQSSEEQMVQLLQLAIDCVAQVPDARPTMSHVVVRIEE 242 ++ E + +++++A+ C+ RP M +V +E+ Sbjct: 829 PG-IKGGYHAEALWRVVEVALQCLEPYSTYRPCMVDIVRELED 870
>NORK_PEA (Q8LKZ1) Nodulation receptor kinase precursor (EC 2.7.11.1)| Length = 924 Score = 73.6 bits (179), Expect = 6e-13 Identities = 50/163 (30%), Positives = 85/163 (52%), Gaps = 6/163 (3%) Frame = -1 Query: 712 YIHS-TSSSTSHGNIKSSNILLSKAYQARVSDNGLATLV----GSSSSGPSRAT-GYRAP 551 Y+H+ S H ++KSSNILL + A+V+D G + S S R T GY P Sbjct: 708 YLHTFPGRSVIHRDVKSSNILLDHSMCAKVADFGFSKYAPQEGDSYVSLEVRGTAGYLDP 767 Query: 550 EVTDPRRVSQKADVFSFGVLLLELLTGKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFD 371 E +++S+K+DVFSFGV+LLE+++G+ P L W + +R+ E+ D Sbjct: 768 EYYKTQQLSEKSDVFSFGVVLLEIVSGREPLNIKRPRVEWSLVEWAKPYIRASKVDEIVD 827 Query: 370 MELLRNQSSEEQMVQLLQLAIDCVAQVPDARPTMSHVVVRIEE 242 ++ E + +++++A+ C+ RP M +V +E+ Sbjct: 828 PG-IKGGYHAEALWRVVEVALQCLEPYSTYRPCMVDIVRELED 869
>CRI4_MAIZE (O24585) Putative receptor protein kinase CRINKLY4 precursor (EC| 2.7.11.1) Length = 901 Score = 72.4 bits (176), Expect = 1e-12 Identities = 53/164 (32%), Positives = 86/164 (52%), Gaps = 7/164 (4%) Frame = -1 Query: 715 EYIHSTSSS-TSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSG------PSRATGYR 557 EY+H + H +IKSSNIL+ + + ARV+D GL+ L G + SG P+ GY Sbjct: 620 EYLHGYACPPVIHRDIKSSNILIDEDHNARVADFGLSIL-GPADSGTPLSELPAGTLGYL 678 Query: 556 APEVTDPRRVSQKADVFSFGVLLLELLTGKAPSQSALNDEGVDLPRWVQSVVRSEWTSEV 377 PE ++ K+DV+SFGV+LLE+L+G+ +EG ++ W ++++ + Sbjct: 679 DPEYYRLHYLTTKSDVYSFGVVLLEILSGRKAIDMQF-EEG-NIVEWAVPLIKAGDIFAI 736 Query: 376 FDMELLRNQSSEEQMVQLLQLAIDCVAQVPDARPTMSHVVVRIE 245 D +L S E + ++ +A CV RP+M V +E Sbjct: 737 LD-PVLSPPSDLEALKKIASVACKCVRMRGKDRPSMDKVTTALE 779
>KPRO_MAIZE (P17801) Putative receptor protein kinase ZmPK1 precursor (EC| 2.7.11.1) Length = 817 Score = 72.0 bits (175), Expect = 2e-12 Identities = 52/155 (33%), Positives = 79/155 (50%), Gaps = 13/155 (8%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLV--GSSSSGPSRATG---YRAPEVTDPRRVSQK 518 H ++K NILL +A++ +++D GL L+ G S+ S G Y APE ++ K Sbjct: 656 HCDVKPENILLDQAFEPKITDFGLVKLLNRGGSTQNVSHVRGTLGYIAPEWVSSLPITAK 715 Query: 517 ADVFSFGVLLLELLTGKAPSQSALNDEGV-----DLPRWVQSVVRSE---WTSEVFDMEL 362 DV+S+GV+LLELLTG S+ + V L R + + + E W D +L Sbjct: 716 VDVYSYGVVLLELLTGTRVSELVGGTDEVHSMLRKLVRMLSAKLEGEEQSWIDGYLDSKL 775 Query: 361 LRNQSSEEQMVQLLQLAIDCVAQVPDARPTMSHVV 257 R + Q L++LA+ C+ + RPTM H V Sbjct: 776 NR-PVNYVQARTLIKLAVSCLEEDRSKRPTMEHAV 809
>CX32_ARATH (P27450) Probable serine/threonine-protein kinase Cx32, chloroplast| precursor (EC 2.7.11.1) Length = 419 Score = 71.6 bits (174), Expect = 2e-12 Identities = 47/166 (28%), Positives = 81/166 (48%), Gaps = 7/166 (4%) Frame = -1 Query: 712 YIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRAT-------GYRA 554 ++HS + + K+SNILL Y A++SD GLA L + S T GY A Sbjct: 206 FLHSLQREVIYRDFKASNILLDSNYDAKLSDFGLAKL--GPADEKSHVTTRIMGTYGYAA 263 Query: 553 PEVTDPRRVSQKADVFSFGVLLLELLTGKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVF 374 PE + K+DVF+FGV+LLE++TG + L W++ + ++ + Sbjct: 264 PEYMATGHLYVKSDVFAFGVVLLEIMTGLTAHNTKRPRGQESLVDWLRPELSNKHRVKQI 323 Query: 373 DMELLRNQSSEEQMVQLLQLAIDCVAQVPDARPTMSHVVVRIEEIK 236 + ++ Q + + ++ ++ + C+ P RP M VV +E I+ Sbjct: 324 MDKGIKGQYTTKVATEMARITLSCIEPDPKNRPHMKEVVEVLEHIQ 369
>SRK6_BRAOE (Q09092) Putative serine/threonine-protein kinase receptor precursor| (EC 2.7.11.1) (S-receptor kinase) (SRK) Length = 849 Score = 68.6 bits (166), Expect = 2e-11 Identities = 50/164 (30%), Positives = 85/164 (51%), Gaps = 12/164 (7%) Frame = -1 Query: 712 YIHSTSS-STSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRAT-----GYRAP 551 Y+H S H ++K SNILL K ++SD G+A + + + GY +P Sbjct: 640 YLHQDSRFRIIHRDLKVSNILLDKNMIPKISDFGMARIFERDETEANTMKVVGTYGYMSP 699 Query: 550 EVTDPRRVSQKADVFSFGVLLLELLTGKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFD 371 E S+K+DVFSFGV++LE+++GK D DL +V S + E+ D Sbjct: 700 EYAMYGIFSEKSDVFSFGVIVLEIVSGKKNRGFYNLDYENDLLSYVWSRWKEGRALEIVD 759 Query: 370 MELLRNQSSE------EQMVQLLQLAIDCVAQVPDARPTMSHVV 257 ++ + SS+ +++++ +Q+ + CV ++ + RP MS VV Sbjct: 760 PVIVDSLSSQPSIFQPQEVLKCIQIGLLCVQELAEHRPAMSSVV 803
>PBS1_ARATH (Q9FE20) Serine/threonine-protein kinase PBS1 (EC 2.7.11.1)| (AvrPphB susceptible protein 1) Length = 456 Score = 67.0 bits (162), Expect = 5e-11 Identities = 47/162 (29%), Positives = 79/162 (48%), Gaps = 6/162 (3%) Frame = -1 Query: 715 EYIHSTSSS-TSHGNIKSSNILLSKAYQARVSDNGLATL--VGSSSSGPSRATG---YRA 554 E++H ++ + + KSSNILL + + ++SD GLA L G S +R G Y A Sbjct: 199 EFLHDKANPPVIYRDFKSSNILLDEGFHPKLSDFGLAKLGPTGDKSHVSTRVMGTYGYCA 258 Query: 553 PEVTDPRRVSQKADVFSFGVLLLELLTGKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVF 374 PE +++ K+DV+SFGV+ LEL+TG+ S + +L W + + Sbjct: 259 PEYAMTGQLTVKSDVYSFGVVFLELITGRKAIDSEMPHGEQNLVAWARPLFNDRRKFIKL 318 Query: 373 DMELLRNQSSEEQMVQLLQLAIDCVAQVPDARPTMSHVVVRI 248 L+ + + Q L +A C+ + RP ++ VV + Sbjct: 319 ADPRLKGRFPTRALYQALAVASMCIQEQAATRPLIADVVTAL 360
>M3LK7_DROME (P83104) Putative mitogen-activated protein kinase kinase kinase| 7-like (EC 2.7.11.25) Length = 393 Score = 63.5 bits (153), Expect = 6e-10 Identities = 43/152 (28%), Positives = 74/152 (48%), Gaps = 1/152 (0%) Frame = -1 Query: 712 YIHSTSSSTSHGNIKSSNILLSKAYQ-ARVSDNGLATLVGSSSSGPSRATGYRAPEVTDP 536 Y+HS H +IK N+LL ++ ++ D GLAT + ++ + Y APE Sbjct: 121 YLHSLDRPIVHRDIKPQNMLLYNQHEDLKICDFGLATDMSNNKTDMQGTLRYMAPEAIKH 180 Query: 535 RRVSQKADVFSFGVLLLELLTGKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFDMELLR 356 + + K DV+SFG++L EL+T + P N P +++++ + E ME +R Sbjct: 181 LKYTAKCDVYSFGIMLWELMTRQLPYSHLEN------PNSQYAIMKAISSGEKLPMEAVR 234 Query: 355 NQSSEEQMVQLLQLAIDCVAQVPDARPTMSHV 260 + E + QL C+ P+ RP+M + Sbjct: 235 SDCPE----GIKQLMECCMDINPEKRPSMKEI 262
>YR831_MIMIV (Q7T6Y2) Putative serine/threonine-protein kinase/receptor R831| precursor (EC 2.7.11.1) Length = 1624 Score = 62.8 bits (151), Expect = 1e-09 Identities = 32/86 (37%), Positives = 54/86 (62%), Gaps = 1/86 (1%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATG-YRAPEVTD 539 +Y+HS++ H +IK +NIL+ + + +++D G A + +++ T + APEV Sbjct: 1474 DYLHSSNPMIVHRDIKPANILVDEHFNVKIADFGFARIKEDNTTMTRCGTPCWTAPEVIR 1533 Query: 538 PRRVSQKADVFSFGVLLLELLTGKAP 461 + +KADVFSFGV++ E+LTGK P Sbjct: 1534 GEKYCEKADVFSFGVVMWEVLTGKEP 1559 Score = 45.4 bits (106), Expect = 2e-04 Identities = 42/160 (26%), Positives = 67/160 (41%), Gaps = 7/160 (4%) Frame = -1 Query: 697 SSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSR-----ATGYRAPEV-TDP 536 SS H ++KS N+LL + +VSD GL + + + APE+ D Sbjct: 901 SSGIVHRDLKSLNLLLDSKWNVKVSDFGLTKVKSELDKKKTNDNIIGTIHWIAPEILNDS 960 Query: 535 RRVSQ-KADVFSFGVLLLELLTGKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFDMELL 359 V ADV+SFG++L ELLT + P +G+ SV+R + D Sbjct: 961 TEVDYILADVYSFGIILWELLTREQPY------KGMTPAAIAVSVIRDGMRPPISD---- 1010 Query: 358 RNQSSEEQMVQLLQLAIDCVAQVPDARPTMSHVVVRIEEI 239 ++ ++ + L C RPT ++ R+ I Sbjct: 1011 --EAVTAHSIEYIDLIKQCWHSDTIIRPTFLEIMTRLSNI 1048
>RIPK3_RAT (Q9Z2P5) Receptor-interacting serine/threonine-protein kinase 3 (EC| 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) (Homocysteine respondent protein HCYP2) Length = 478 Score = 61.2 bits (147), Expect = 3e-09 Identities = 37/90 (41%), Positives = 55/90 (61%), Gaps = 8/90 (8%) Frame = -1 Query: 712 YIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGP---SRATG----YRA 554 Y+HS + S H ++K SN+LL A+++D GL+T G S SG SR +G Y A Sbjct: 131 YLHSLNPSLLHRDLKPSNVLLDLELHAKLADFGLSTFQGGSQSGSGSGSRDSGGTLAYLA 190 Query: 553 PEVTD-PRRVSQKADVFSFGVLLLELLTGK 467 PE+ D + S+ +DV+SFGVL+ +L G+ Sbjct: 191 PELLDNDGKASKASDVYSFGVLVWTVLAGR 220
>KPEL_DROME (Q05652) Probable serine/threonine-protein kinase pelle (EC| 2.7.11.1) Length = 501 Score = 60.1 bits (144), Expect = 7e-09 Identities = 44/156 (28%), Positives = 71/156 (45%), Gaps = 10/156 (6%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATG------YRAPEVTDPRRVSQ 521 HG+IK +NILL + Q ++ D GL S Y PE + R++S Sbjct: 344 HGDIKPANILLDQCLQPKIGDFGLVREGPKSLDAVVEVNKVFGTKIYLPPEFRNFRQLST 403 Query: 520 KADVFSFGVLLLELLTGKAPSQSALNDEGVDLPRWVQSVVRSEWTS---EVFDMELLRNQ 350 DV+SFG++LLE+ TG+ + +E + + V+ +W E+ + L Sbjct: 404 GVDVYSFGIVLLEVFTGRQVTDRVPENE---TKKNLLDYVKQQWRQNRMELLEKHLAAPM 460 Query: 349 SSEEQMVQ-LLQLAIDCVAQVPDARPTMSHVVVRIE 245 E M ++ + C A P RP+M+ V+ R E Sbjct: 461 GKELDMCMCAIEAGLHCTALDPQDRPSMNAVLKRFE 496
>CTR1_ARATH (Q05609) Serine/threonine-protein kinase CTR1 (EC 2.7.11.1)| Length = 821 Score = 60.1 bits (144), Expect = 7e-09 Identities = 39/128 (30%), Positives = 65/128 (50%), Gaps = 17/128 (13%) Frame = -1 Query: 712 YIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATG---YRAPEVT 542 Y+H+ + H ++KS N+L+ K Y +V D GL+ L S+ A G + APEV Sbjct: 664 YLHNRNPPIVHRDLKSPNLLVDKKYTVKVCDFGLSRLKASTFLSSKSAAGTPEWMAPEVL 723 Query: 541 DPRRVSQKADVFSFGVLLLELLTGKAP----------SQSALNDEGVDLPR----WVQSV 404 ++K+DV+SFGV+L EL T + P + + +++PR V ++ Sbjct: 724 RDEPSNEKSDVYSFGVILWELATLQQPWGNLNPAQVVAAVGFKCKRLEIPRNLNPQVAAI 783 Query: 403 VRSEWTSE 380 + WT+E Sbjct: 784 IEGCWTNE 791
>IRAK4_MOUSE (Q8R4K2) Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1)| (IRAK-4) Length = 459 Score = 58.9 bits (141), Expect = 1e-08 Identities = 49/156 (31%), Positives = 79/156 (50%), Gaps = 8/156 (5%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLA--------TLVGSSSSGPSRATGYRAPEVTDPRRV 527 H +IKS+NILL K + A++SD GLA T++ S G T Y APE + Sbjct: 309 HRDIKSANILLDKDFTAKISDFGLARASARLAQTVMTSRIVG---TTAYMAPEALRGE-I 364 Query: 526 SQKADVFSFGVLLLELLTGKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFDMELLRNQS 347 + K+D++SFGV+LLEL+TG A N E L + + E T E + E + + + Sbjct: 365 TPKSDIYSFGVVLLELITGLAAVDE--NREPQLLLDIKEEIEDEEKTIEDYTDEKM-SDA 421 Query: 346 SEEQMVQLLQLAIDCVAQVPDARPTMSHVVVRIEEI 239 + + A C+ + + RP ++ V ++E+ Sbjct: 422 DPASVEAMYSAASQCLHEKKNRRPDIAKVQQLLQEM 457
>ANPRB_HUMAN (P20594) Atrial natriuretic peptide receptor B precursor (ANP-B)| (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor) Length = 1047 Score = 57.8 bits (138), Expect = 3e-08 Identities = 50/160 (31%), Positives = 79/160 (49%), Gaps = 9/160 (5%) Frame = -1 Query: 712 YIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATG----YRAPEV 545 ++H++ S SHG++KSSN ++ + +++D GLA+ ++ S A + APE+ Sbjct: 633 FLHNSIIS-SHGSLKSSNCVVDSRFVLKITDYGLASFRSTAEPDDSHALYAKKLWTAPEL 691 Query: 544 TD----PRRVSQKADVFSFGVLLLELLTGKAPSQSALNDEGVDL-PRWVQSVVRSEWTSE 380 P QKADV+SFG++L E+ P EG+DL P+ + VR+ Sbjct: 692 LSGNPLPTTGMQKADVYSFGIILQEIALRSGPFYL----EGLDLSPKEIVQKVRN-GQRP 746 Query: 379 VFDMELLRNQSSEEQMVQLLQLAIDCVAQVPDARPTMSHV 260 F + R Q +EE L+ L C AQ P RP + Sbjct: 747 YFRPSIDRTQLNEE----LVLLMERCWAQDPAERPDFGQI 782
>RIPK3_HUMAN (Q9Y572) Receptor-interacting serine/threonine-protein kinase 3 (EC| 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) Length = 518 Score = 57.4 bits (137), Expect = 4e-08 Identities = 36/104 (34%), Positives = 55/104 (52%), Gaps = 10/104 (9%) Frame = -1 Query: 712 YIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSG-----PSRATGYRAPE 548 Y+H + H ++K SN+L +++D GL+T G S SG P GY APE Sbjct: 130 YLHDQNPVLLHRDLKPSNVLPDPELHVKLADFGLSTFQGGSQSGTGSGEPGGTLGYLAPE 189 Query: 547 --VTDPRRVSQKADVFSFGVLLLELLTGK---APSQSALNDEGV 431 V R+ S +DV+SFG+L+ +L G+ P++ +L E V Sbjct: 190 LFVNVNRKASTASDVYSFGILMWAVLAGREVELPTEPSLVYEAV 233
>ANPRB_BOVIN (P46197) Atrial natriuretic peptide receptor B precursor (ANP-B)| (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor) Length = 1047 Score = 57.4 bits (137), Expect = 4e-08 Identities = 50/160 (31%), Positives = 78/160 (48%), Gaps = 9/160 (5%) Frame = -1 Query: 712 YIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATG----YRAPEV 545 ++H+ S SHG++KSSN ++ + +++D GLA+ ++ S A + APE+ Sbjct: 633 FLHN-SIIASHGSLKSSNCVVDSRFVLKITDYGLASFRSTAEPDDSHALYAKKLWTAPEL 691 Query: 544 TD----PRRVSQKADVFSFGVLLLELLTGKAPSQSALNDEGVDL-PRWVQSVVRSEWTSE 380 P QKADV+SFG++L E+ P EG+DL P+ + VR+ Sbjct: 692 LSGNPLPTTGMQKADVYSFGIILQEIALRSGPFYL----EGLDLSPKEIVQKVRN-GQRP 746 Query: 379 VFDMELLRNQSSEEQMVQLLQLAIDCVAQVPDARPTMSHV 260 F + R Q +EE L+ L C AQ P RP + Sbjct: 747 YFRPSIDRTQLNEE----LVLLMERCWAQDPAERPDFGQI 782
>IRAK1_HUMAN (P51617) Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1)| (IRAK-1) Length = 712 Score = 57.0 bits (136), Expect = 6e-08 Identities = 53/198 (26%), Positives = 87/198 (43%), Gaps = 38/198 (19%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRAT---------- 566 +++H S S HG+IKSSN+LL + ++ D GLA + S PS+++ Sbjct: 327 QFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRG 386 Query: 565 --GYRAPEVTDPRRVSQKADVFSFGVLLLELLTG--------------KAPSQSALNDEG 434 Y E R++ D FSFGV++LE L G K + + G Sbjct: 387 TLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAG 446 Query: 433 VDLPRWVQSVVRS-----EWTSEVFDMELLRNQ-------SSEEQMVQLLQLAIDCVAQV 290 V L R QS +++ W + + M++ + E + L QLA C+ + Sbjct: 447 VAL-RSTQSTLQAGLAADAWAAPI-AMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRR 504 Query: 289 PDARPTMSHVVVRIEEIK 236 RP M+ V R+E+++ Sbjct: 505 AKRRPPMTQVYERLEKLQ 522
>IRAK4_HUMAN (Q9NWZ3) Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1)| (IRAK-4) (NY-REN-64 antigen) Length = 460 Score = 57.0 bits (136), Expect = 6e-08 Identities = 44/156 (28%), Positives = 80/156 (51%), Gaps = 8/156 (5%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLA--------TLVGSSSSGPSRATGYRAPEVTDPRRV 527 H +IKS+NILL +A+ A++SD GLA T++ S G T Y APE + Sbjct: 309 HRDIKSANILLDEAFTAKISDFGLARASEKFAQTVMTSRIVG---TTAYMAPEAL-RGEI 364 Query: 526 SQKADVFSFGVLLLELLTGKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFDMELLRNQS 347 + K+D++SFGV+LLE++TG P+ + + L ++ + E + ++ N + Sbjct: 365 TPKSDIYSFGVVLLEIITG-LPAVDEHREPQLLLD--IKEEIEDEEKTIEDYIDKKMNDA 421 Query: 346 SEEQMVQLLQLAIDCVAQVPDARPTMSHVVVRIEEI 239 + + +A C+ + + RP + V ++E+ Sbjct: 422 DSTSVEAMYSVASQCLHEKKNKRPDIKKVQQLLQEM 457
>LCK_HUMAN (P06239) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell-specific protein-tyrosine kinase) Length = 508 Score = 56.6 bits (135), Expect = 7e-08 Identities = 41/152 (26%), Positives = 77/152 (50%), Gaps = 5/152 (3%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSS----SGPSRATGYRAPEVTDPRRVSQKA 515 H +++++NIL+S +++D GLA L+ + G + APE + + K+ Sbjct: 361 HRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKS 420 Query: 514 DVFSFGVLLLELLT-GKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFDMELLRNQSSEE 338 DV+SFG+LL E++T G+ P N P +Q++ R ++R + E Sbjct: 421 DVWSFGILLTEIVTHGRIPYPGMTN------PEVIQNLERG--------YRMVRPDNCPE 466 Query: 337 QMVQLLQLAIDCVAQVPDARPTMSHVVVRIEE 242 ++ QL++L C + P+ RPT ++ +E+ Sbjct: 467 ELYQLMRL---CWKERPEDRPTFDYLRSVLED 495
>PKPA_PHYBL (Q01577) Serine/threonine-protein kinase pkpA (EC 2.7.11.1)| Length = 613 Score = 56.2 bits (134), Expect = 1e-07 Identities = 34/119 (28%), Positives = 59/119 (49%), Gaps = 1/119 (0%) Frame = -1 Query: 712 YIHSTSSSTSHGNIKSSNILLSKAY-QARVSDNGLATLVGSSSSGPSRATGYRAPEVTDP 536 Y+H H +IK NI ++ A+ + ++ D G A + + APE+ + Sbjct: 128 YLHGHEPPIIHRDIKCDNIFINGAHGEIKIGDMGTAEMKNGKKYTVIGTPEFMAPEMYEE 187 Query: 535 RRVSQKADVFSFGVLLLELLTGKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFDMELL 359 + ++K D+++FG+ LLE+ TG+ P N V + + V ++ E S V D ELL Sbjct: 188 QGYNEKVDIYAFGMCLLEMATGEYPYGECTN--AVQVFKKVTQTIKPECLSRVQDPELL 244
>KYK1_DICDI (P18160) Non-receptor tyrosine kinase spore lysis A (EC 2.7.10.2)| (Tyrosine-protein kinase 1) Length = 1584 Score = 56.2 bits (134), Expect = 1e-07 Identities = 45/175 (25%), Positives = 79/175 (45%), Gaps = 16/175 (9%) Frame = -1 Query: 712 YIHSTSSSTSHGNIKSSNILLS-------------KAYQARVSDNGLATLVGSSSSGPSR 572 Y+H + H ++ S NILL + + ++SD GL+ L +S ++ Sbjct: 1405 YLHGWTPPILHRDLSSRNILLDHNIDPKNPVVSSRQDIKCKISDFGLSRLKKEQASQMTQ 1464 Query: 571 ATG---YRAPEVTDPRRVSQKADVFSFGVLLLELLTGKAPSQSALNDEGVDLPRWVQSVV 401 + G Y APEV S+K+DV+S+G++L ELLT P Q + L + Sbjct: 1465 SVGCIPYMAPEVFKGDSNSEKSDVYSYGMVLFELLTSDEPQQDMKPMKMAHLAAY----- 1519 Query: 400 RSEWTSEVFDMELLRNQSSEEQMVQLLQLAIDCVAQVPDARPTMSHVVVRIEEIK 236 E + + SS+ + ++ C PD+RPT ++V ++E++ Sbjct: 1520 ------ESYRPPIPLTTSSKWK-----EILTQCWDSNPDSRPTFKQIIVHLKEME 1563
>ANPRB_RAT (P16067) Atrial natriuretic peptide receptor B precursor (ANP-B)| (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor) Length = 1047 Score = 55.8 bits (133), Expect = 1e-07 Identities = 49/160 (30%), Positives = 78/160 (48%), Gaps = 9/160 (5%) Frame = -1 Query: 712 YIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATG----YRAPEV 545 ++H++ S SHG++KSSN ++ + +++D GLA+ ++ S A + APE+ Sbjct: 633 FLHNSIIS-SHGSLKSSNCVVDSRFVLKITDYGLASFRSTAEPDDSHALYAKKLWTAPEL 691 Query: 544 TD----PRRVSQKADVFSFGVLLLELLTGKAPSQSALNDEGVDL-PRWVQSVVRSEWTSE 380 P QKADV+SF ++L E+ P EG+DL P+ + VR+ Sbjct: 692 LSGNPLPTTGMQKADVYSFAIILQEIALRSGPFYL----EGLDLSPKEIVQKVRN-GQRP 746 Query: 379 VFDMELLRNQSSEEQMVQLLQLAIDCVAQVPDARPTMSHV 260 F + R Q +EE L+ L C AQ P RP + Sbjct: 747 YFRPSIDRTQLNEE----LVLLMERCWAQDPTERPDFGQI 782
>ANPRB_MOUSE (Q6VVW5) Atrial natriuretic peptide receptor B precursor (ANP-B)| (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor) Length = 1047 Score = 55.8 bits (133), Expect = 1e-07 Identities = 49/160 (30%), Positives = 78/160 (48%), Gaps = 9/160 (5%) Frame = -1 Query: 712 YIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATG----YRAPEV 545 ++H++ S SHG++KSSN ++ + +++D GLA+ ++ S A + APE+ Sbjct: 633 FLHNSIIS-SHGSLKSSNCVVDSRFVLKITDYGLASFRSTAEPDDSHALYAKKLWTAPEL 691 Query: 544 TD----PRRVSQKADVFSFGVLLLELLTGKAPSQSALNDEGVDL-PRWVQSVVRSEWTSE 380 P QKADV+SF ++L E+ P EG+DL P+ + VR+ Sbjct: 692 LSGNPLPTTGMQKADVYSFAIILQEIALRSGPFYL----EGLDLSPKEIVQKVRN-GQRP 746 Query: 379 VFDMELLRNQSSEEQMVQLLQLAIDCVAQVPDARPTMSHV 260 F + R Q +EE L+ L C AQ P RP + Sbjct: 747 YFRPSIDRTQLNEE----LVLLMERCWAQDPTERPDFGQI 782
>IRAK1_MOUSE (Q62406) Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1)| (IRAK-1) (IRAK) (Pelle-like protein kinase) (mPLK) Length = 710 Score = 55.5 bits (132), Expect = 2e-07 Identities = 54/197 (27%), Positives = 84/197 (42%), Gaps = 37/197 (18%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATL------VGSSSSGPSRAT---- 566 +++H S S HG+IKSSN+LL + ++ D GLA S SS +R + Sbjct: 327 QFLHQDSPSLIHGDIKSSNVLLDERLMPKLGDFGLARFSRFAGAKASQSSTVARTSTVRG 386 Query: 565 --GYRAPEVTDPRRVSQKADVFSFGVLLLELLTGKAPSQS----------ALNDE----G 434 Y E R++ D FSFGV++LE L G+ ++ + DE G Sbjct: 387 TLAYLPEEYIKTGRLAVDTDTFSFGVVILETLAGQRAVRTQGAKTKYLKDLIEDEAEEAG 446 Query: 433 VDLPR-----WVQSVVRSEWTSEVFDMELLRNQSSE------EQMVQLLQLAIDCVAQVP 287 V L WV V W + + ++ S + + L QLA C+ + Sbjct: 447 VTLKSTQPTLWV-GVATDAWAAPIAAQIYKKHLDSRPGPCPPQLGLALAQLACCCMHRRA 505 Query: 286 DARPTMSHVVVRIEEIK 236 RP M+ V R+E ++ Sbjct: 506 KKRPPMTQVYKRLEGLQ 522
>RAF1_HUMAN (P04049) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Raf-1) (C-RAF) (cRaf) Length = 648 Score = 55.5 bits (132), Expect = 2e-07 Identities = 47/165 (28%), Positives = 82/165 (49%), Gaps = 8/165 (4%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVG--SSSSGPSRATG---YRAP 551 +Y+H+ + H ++KS+NI L + ++ D GLAT+ S S + TG + AP Sbjct: 457 DYLHA--KNIIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAP 514 Query: 550 EVT---DPRRVSQKADVFSFGVLLLELLTGKAPSQSALNDEGVDLPRWVQSVVRSEWTSE 380 EV D S ++DV+S+G++L EL+TG+ P N + + + V R + + Sbjct: 515 EVIRMQDNNPFSFQSDVYSYGIVLYELMTGELPYSHINNRDQI-----IFMVGRGYASPD 569 Query: 379 VFDMELLRNQSSEEQMVQLLQLAIDCVAQVPDARPTMSHVVVRIE 245 + +L +N + +L DCV +V + RP ++ IE Sbjct: 570 L--SKLYKNCPK-----AMKRLVADCVKKVKEERPLFPQILSSIE 607
>RIPK3_MOUSE (Q9QZL0) Receptor-interacting serine/threonine-protein kinase 3 (EC| 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) (mRIP3) Length = 486 Score = 55.5 bits (132), Expect = 2e-07 Identities = 46/169 (27%), Positives = 72/169 (42%), Gaps = 11/169 (6%) Frame = -1 Query: 712 YIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATGYRAPEVT--- 542 Y+HS H ++K SNILL A+++D GL+T G S SG +G R T Sbjct: 131 YLHSLDPPLLHRDLKPSNILLDPELHAKLADFGLSTFQGGSQSGSGSGSGSRDSGGTLAY 190 Query: 541 -DPR-------RVSQKADVFSFGVLLLELLTGKAPSQSALNDEGVDLPRWVQSVVRSEWT 386 DP + S+ +DV+SFG+L+ +L G+ E VD ++ V + Sbjct: 191 LDPELLFKVNLKASKASDVYSFGILVWAVLAGR-------EAELVDKTSLIRETVCDRQS 243 Query: 385 SEVFDMELLRNQSSEEQMVQLLQLAIDCVAQVPDARPTMSHVVVRIEEI 239 EL + +L +L I C + RP+ + E+ Sbjct: 244 RPPL-TELPPGSPETPGLEKLKELMIHCWGSQSENRPSFQDCEPKTNEV 291
>RAF1_RAT (P11345) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Raf-1) (C-RAF) (cRaf) Length = 648 Score = 55.1 bits (131), Expect = 2e-07 Identities = 47/165 (28%), Positives = 81/165 (49%), Gaps = 8/165 (4%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVG--SSSSGPSRATG---YRAP 551 +Y+H+ + H ++KS+NI L + ++ D GLAT+ S S + TG + AP Sbjct: 457 DYLHA--KNIIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAP 514 Query: 550 EVT---DPRRVSQKADVFSFGVLLLELLTGKAPSQSALNDEGVDLPRWVQSVVRSEWTSE 380 EV D S ++DV+S+G++L EL+TG+ P N + + + V R + + Sbjct: 515 EVIRMQDNNPFSFQSDVYSYGIVLYELMTGELPYSHINNRDQI-----IFMVGRGYASPD 569 Query: 379 VFDMELLRNQSSEEQMVQLLQLAIDCVAQVPDARPTMSHVVVRIE 245 + L +N + +L DCV +V + RP ++ IE Sbjct: 570 L--SRLYKNCPK-----AMKRLVADCVKKVKEERPLFPQILSSIE 607
>GCY1_CAEEL (Q09435) Guanylate cyclase receptor-type gcy-1 precursor (EC 4.6.1.2)| Length = 1137 Score = 54.7 bits (130), Expect = 3e-07 Identities = 43/163 (26%), Positives = 78/163 (47%), Gaps = 11/163 (6%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATGYRAPEVT-- 542 EY+H T HGN++S+ L++ ++Q ++++ G+ LV + P + + APEV Sbjct: 672 EYLHKTFLRL-HGNLRSATCLVNDSWQVKLAEYGMDNLV-EEQTPPKKRLLWVAPEVLRG 729 Query: 541 --DPRRVSQKADVFSFGVLLLELLTGKAPSQSALNDEGVDLPRWVQSV-------VRSEW 389 ++ AD++SF ++ E+LT K + D D V +V +R E Sbjct: 730 SLSVSQMEPSADIYSFAIIASEILTKKEAWD--ILDRKEDCEEIVYNVKKGGLFPIRPEI 787 Query: 388 TSEVFDMELLRNQSSEEQMVQLLQLAIDCVAQVPDARPTMSHV 260 +++ D+ L+ L DC A+VP+ RPT ++ Sbjct: 788 ITDIHDVN-----------PALIALVKDCWAEVPEDRPTAENI 819
>LCK_CHICK (P42683) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (Protein-tyrosine kinase C-TKL) (p56tk1) Length = 507 Score = 54.7 bits (130), Expect = 3e-07 Identities = 40/152 (26%), Positives = 74/152 (48%), Gaps = 5/152 (3%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSS----SGPSRATGYRAPEVTDPRRVSQKA 515 H +++++NIL+S+A +++D GLA L+ + G + APE + + K+ Sbjct: 360 HRDLRAANILVSEALCCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKS 419 Query: 514 DVFSFGVLLLELLT-GKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFDMELLRNQSSEE 338 DV+SFG+LL E++T G+ P N P +Q++ R R + Sbjct: 420 DVWSFGILLTEIVTYGRIPYPGMTN------PEVIQNLERG-----------YRMPQPDN 462 Query: 337 QMVQLLQLAIDCVAQVPDARPTMSHVVVRIEE 242 +L +L + C + P+ RPT ++ +E+ Sbjct: 463 CPQELYELMMQCWKEQPEERPTFEYMKSVLED 494
>M3K11_HUMAN (Q16584) Mitogen-activated protein kinase kinase kinase 11 (EC| 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline-rich kinase) Length = 847 Score = 54.7 bits (130), Expect = 3e-07 Identities = 46/158 (29%), Positives = 77/158 (48%), Gaps = 9/158 (5%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQA--------RVSDNGLATLVGSSSSGPSRAT-GYRAPEVTDPRR 530 H ++KS+NILL + ++ +++D GLA ++ + T + APEV Sbjct: 239 HRDLKSNNILLLQPIESDDMEHKTLKITDFGLAREWHKTTQMSAAGTYAWMAPEVIKAST 298 Query: 529 VSQKADVFSFGVLLLELLTGKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFDMELLRNQ 350 S+ +DV+SFGVLL ELLTG+ P + G+D V ++ T + Sbjct: 299 FSKGSDVWSFGVLLWELLTGEVPYR------GIDCLAVAYGVAVNKLTLPI-------PS 345 Query: 349 SSEEQMVQLLQLAIDCVAQVPDARPTMSHVVVRIEEIK 236 + E QL+ DC AQ P RP + ++ ++E ++ Sbjct: 346 TCPEPFAQLM---ADCWAQDPHRRPDFASILQQLEALE 380
>SRMS_MOUSE (Q62270) Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70)| Length = 496 Score = 54.7 bits (130), Expect = 3e-07 Identities = 38/100 (38%), Positives = 53/100 (53%), Gaps = 12/100 (12%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATL----VGSSSSGPSRATGYRAPEVTDPRRVSQKA 515 H ++ + N+L+ +V+D GLA L V S SSG + APE + R SQK+ Sbjct: 352 HRDLAARNVLVGDDLTCKVADFGLARLLKDDVYSPSSGSKIPVKWTAPEAANYRVFSQKS 411 Query: 514 DVFSFGVLLLELLT-GKAPSQSALNDE-------GVDLPR 419 DV+SFG+LL E+ T G+ P + N E G LPR Sbjct: 412 DVWSFGILLYEVFTYGQCPYEGMTNHETLQQISRGYRLPR 451
>RAF1_CHICK (P05625) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (RAF-1) (C-RAF) (MIL proto-oncogene serine/threonine-protein kinase) (C-MIL) Length = 647 Score = 54.3 bits (129), Expect = 4e-07 Identities = 46/165 (27%), Positives = 82/165 (49%), Gaps = 8/165 (4%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVG--SSSSGPSRATG---YRAP 551 +Y+H+ + H ++KS+NI L + ++ D GLAT+ S S + TG + AP Sbjct: 457 DYLHA--KNIIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSILWMAP 514 Query: 550 EVT---DPRRVSQKADVFSFGVLLLELLTGKAPSQSALNDEGVDLPRWVQSVVRSEWTSE 380 EV D S ++DV+S+G++L EL+TG+ P N + + + V R + + Sbjct: 515 EVIRMQDSNPFSFQSDVYSYGIVLYELMTGELPYSHINNRDQI-----IFMVGRGYASPD 569 Query: 379 VFDMELLRNQSSEEQMVQLLQLAIDCVAQVPDARPTMSHVVVRIE 245 + +L +N + +L DC+ +V + RP ++ IE Sbjct: 570 L--SKLYKNCPK-----AMKRLVADCLKKVREERPLFPQILSSIE 607
>LCK_AOTNA (Q5PXS1) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) Length = 508 Score = 54.3 bits (129), Expect = 4e-07 Identities = 40/152 (26%), Positives = 75/152 (49%), Gaps = 5/152 (3%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSS----SGPSRATGYRAPEVTDPRRVSQKA 515 H +++++NIL+S +++D GLA L+ + G + APE + + K+ Sbjct: 361 HRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKS 420 Query: 514 DVFSFGVLLLELLT-GKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFDMELLRNQSSEE 338 DV+SFG+LL E++T G+ P N P +Q++ R ++R + E Sbjct: 421 DVWSFGILLTEIVTHGRIPYPGMTN------PEVIQNLERG--------YRMVRPDNCPE 466 Query: 337 QMVQLLQLAIDCVAQVPDARPTMSHVVVRIEE 242 ++ L+ L C + P+ RPT ++ +E+ Sbjct: 467 ELYHLMML---CWKERPEDRPTFDYLRSVLED 495
>M3K13_HUMAN (O43283) Mitogen-activated protein kinase kinase kinase 13 (EC| 2.7.11.25) (Mixed lineage kinase) (MLK) (Leucine zipper-bearing kinase) Length = 966 Score = 53.9 bits (128), Expect = 5e-07 Identities = 30/76 (39%), Positives = 46/76 (60%), Gaps = 2/76 (2%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRA--TGYRAPEVTDPRRVSQKADV 509 H ++KS N+L++ ++SD G + + S+ S A + APEV VS+K D+ Sbjct: 277 HRDLKSPNVLVTHTDAVKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDI 336 Query: 508 FSFGVLLLELLTGKAP 461 +SFGV+L ELLTG+ P Sbjct: 337 WSFGVVLWELLTGEIP 352
>LCK_MOUSE (P06240) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) Length = 508 Score = 53.9 bits (128), Expect = 5e-07 Identities = 39/146 (26%), Positives = 72/146 (49%), Gaps = 5/146 (3%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSS----SGPSRATGYRAPEVTDPRRVSQKA 515 H +++++NIL+S +++D GLA L+ + G + APE + + K+ Sbjct: 361 HRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKS 420 Query: 514 DVFSFGVLLLELLT-GKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFDMELLRNQSSEE 338 DV+SFG+LL E++T G+ P N P +Q++ R ++R + E Sbjct: 421 DVWSFGILLTEIVTHGRIPYPGMTN------PEVIQNLERG--------YRMVRPDNCPE 466 Query: 337 QMVQLLQLAIDCVAQVPDARPTMSHV 260 ++ L+ L C + P+ RPT ++ Sbjct: 467 ELYHLMML---CWKERPEDRPTFDYL 489
>PMK1_CAEEL (Q17446) Mitogen-activated protein kinase pmk-1 (EC 2.7.11.24) (p38| MAP kinase 1) (Stress-activated protein kinase pmk-1) Length = 377 Score = 53.9 bits (128), Expect = 5e-07 Identities = 43/162 (26%), Positives = 76/162 (46%), Gaps = 14/162 (8%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATGYRAPEV-TD 539 +YIHS + H ++K SNI +++ + ++ D GLA S +G YRAPE+ + Sbjct: 150 KYIHS--ADIIHRDLKPSNIAVNEDCELKILDFGLARQTDSEMTGYVATRWYRAPEIMLN 207 Query: 538 PRRVSQKADVFSFGVLLLELLTGKA--PSQSALND-------EGVDLPRWVQSVVRSEWT 386 +Q DV+S G +L EL+TGK P ++ G +++ + E Sbjct: 208 WMHYTQTVDVWSVGCILAELITGKTLFPGSDHIDQLTRIMSVTGTPDEEFLKKISSEEAR 267 Query: 385 SEVFDMELLRNQSSEEQMVQLLQLAIDCVAQV----PDARPT 272 + + ++ + + + Q AID + ++ PD RPT Sbjct: 268 NYIRNLPKMTRRDFKRLFAQATPQAIDLLEKMLHLDPDRRPT 309
>GCY3E_DROME (Q07553) Guanylate cyclase 32E precursor (EC 4.6.1.2)| Length = 1163 Score = 53.9 bits (128), Expect = 5e-07 Identities = 37/93 (39%), Positives = 49/93 (52%), Gaps = 9/93 (9%) Frame = -1 Query: 712 YIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATL-VGSSSSGPSRATGYRA----PE 548 Y+H S SHGN++SSN L+ + ++SD GL L G S RA PE Sbjct: 641 YLHD-SEIISHGNLRSSNCLIDSRWVCQISDFGLHELKAGQEEPNKSELELKRALCMAPE 699 Query: 547 VTD----PRRVSQKADVFSFGVLLLELLTGKAP 461 + P R SQK DV+SFG+LL E++ K P Sbjct: 700 LLRDAYRPGRGSQKGDVYSFGILLYEMIGRKGP 732
>M3K13_PONPY (Q5R8X7) Mitogen-activated protein kinase kinase kinase 13 (EC| 2.7.11.25) Length = 966 Score = 53.5 bits (127), Expect = 6e-07 Identities = 30/76 (39%), Positives = 46/76 (60%), Gaps = 2/76 (2%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRA--TGYRAPEVTDPRRVSQKADV 509 H ++KS N+L++ ++SD G + + S+ S A + APEV VS+K D+ Sbjct: 277 HRDLKSPNVLVTHTDAVKISDFGTSKELSDKSTKMSFAGTVAWLAPEVIRNEPVSEKVDI 336 Query: 508 FSFGVLLLELLTGKAP 461 +SFGV+L ELLTG+ P Sbjct: 337 WSFGVVLWELLTGEIP 352
>ANPRB_ANGJA (P55202) Atrial natriuretic peptide receptor B precursor (ANP-B)| (ANPRB) (GC-B) (Guanylate cyclase) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor) Length = 1050 Score = 53.5 bits (127), Expect = 6e-07 Identities = 46/158 (29%), Positives = 77/158 (48%), Gaps = 9/158 (5%) Frame = -1 Query: 685 SHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATG----YRAPEV----TDPRR 530 SHGN+KSSN ++ + +++D GLA+ S + S A + APE+ P + Sbjct: 645 SHGNLKSSNCVVDSRFVLKITDYGLASFRSSCENEDSHALYAKKLWTAPELLIYDRHPPQ 704 Query: 529 VSQKADVFSFGVLLLELLTGKAPSQSALNDEGVDL-PRWVQSVVRSEWTSEVFDMELLRN 353 +QK DV+SFG++L E+ P +G+DL P+ + VR+ F + Sbjct: 705 GTQKGDVYSFGIILQEIALRNGP----FYVDGMDLSPKEIVQKVRN-GQKPYFRPTTDTS 759 Query: 352 QSSEEQMVQLLQLAIDCVAQVPDARPTMSHVVVRIEEI 239 SEE + L C A+ P RP S++ + + ++ Sbjct: 760 CHSEELSI----LMEGCWAEDPADRPDFSYIKIFVMKL 793
>TEC_MOUSE (P24604) Tyrosine-protein kinase Tec (EC 2.7.10.2)| Length = 630 Score = 53.5 bits (127), Expect = 6e-07 Identities = 43/157 (27%), Positives = 77/157 (49%), Gaps = 5/157 (3%) Frame = -1 Query: 694 SSTSHGNIKSSNILLSKAYQARVSDNGLATLV----GSSSSGPSRATGYRAPEVTDPRRV 527 +S H ++ + N L+++A +VSD G+A V +SSSG + PEV + R Sbjct: 482 NSFIHRDLAARNCLVNEAGVVKVSDFGMARYVLDDQYTSSSGAKFPVKWCPPEVFNYSRF 541 Query: 526 SQKADVFSFGVLLLELLT-GKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFDMELLRNQ 350 S K+DV+SFGVL+ E+ T G+ P + N E V + + R + ++ Sbjct: 542 SSKSDVWSFGVLMWEIFTEGRMPFEKNTNYEVVTMVTRGHRLHRPKLATK---------- 591 Query: 349 SSEEQMVQLLQLAIDCVAQVPDARPTMSHVVVRIEEI 239 L ++ + C + P+ RP++ ++ I+E+ Sbjct: 592 -------YLYEVMLRCWQERPEGRPSLEDLLRTIDEL 621
>CDC15_YEAST (P27636) Cell division control protein 15 (EC 2.7.11.1)| Length = 974 Score = 53.1 bits (126), Expect = 8e-07 Identities = 31/95 (32%), Positives = 53/95 (55%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATGYRAPEVTDP 536 +Y+H H +IK++NILLS +++D G++T+V SS+ + + APE+ Sbjct: 135 KYLHG--EGVIHRDIKAANILLSADNTVKLADFGVSTIVNSSALTLAGTLNWMAPEILGN 192 Query: 535 RRVSQKADVFSFGVLLLELLTGKAPSQSALNDEGV 431 R S +D++S G ++E+LT K P L D + Sbjct: 193 RGASTLSDIWSLGATVVEMLT-KNPPYHNLTDANI 226
>HT1_ARATH (Q2MHE4) Serine/threonine-protein kinase HT1 (EC 2.7.11.1) (High| leaf temperature protein 1) Length = 390 Score = 53.1 bits (126), Expect = 8e-07 Identities = 31/89 (34%), Positives = 48/89 (53%), Gaps = 2/89 (2%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATGYR--APEVT 542 EY+HS H ++KS+N+LL+ + +V+D G + L YR APE+ Sbjct: 201 EYLHS--QGVIHRDLKSNNLLLNDEMRVKVADFGTSCLETQCREAKGNMGTYRWMAPEMI 258 Query: 541 DPRRVSQKADVFSFGVLLLELLTGKAPSQ 455 + ++K DV+SFG++L EL T P Q Sbjct: 259 KEKPYTRKVDVYSFGIVLWELTTALLPFQ 287
>RAF1_MOUSE (Q99N57) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Raf-1) (C-RAF) (cRaf) Length = 648 Score = 53.1 bits (126), Expect = 8e-07 Identities = 46/165 (27%), Positives = 80/165 (48%), Gaps = 8/165 (4%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVG--SSSSGPSRATG---YRAP 551 +Y+H+ + H ++KS+NI L + ++ D GLAT+ S S + TG + AP Sbjct: 457 DYLHA--KNIIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAP 514 Query: 550 EVT---DPRRVSQKADVFSFGVLLLELLTGKAPSQSALNDEGVDLPRWVQSVVRSEWTSE 380 EV D S ++DV+S+G++L EL+ G+ P N + + + V R + + Sbjct: 515 EVIRMQDDNPFSFQSDVYSYGIVLYELMAGELPYAHINNRDQI-----IFMVGRGYASPD 569 Query: 379 VFDMELLRNQSSEEQMVQLLQLAIDCVAQVPDARPTMSHVVVRIE 245 + L +N + +L DCV +V + RP ++ IE Sbjct: 570 L--SRLYKNCPK-----AMKRLVADCVKKVKEERPLFPQILSSIE 607
>RAF_MSV36 (P00532) Serine/threonine-protein kinase transforming protein raf| (EC 2.7.11.1) Length = 323 Score = 53.1 bits (126), Expect = 8e-07 Identities = 46/165 (27%), Positives = 80/165 (48%), Gaps = 8/165 (4%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVG--SSSSGPSRATG---YRAP 551 +Y+H+ + H ++KS+NI L + ++ D GLAT+ S S + TG + AP Sbjct: 132 DYLHA--KNIIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAP 189 Query: 550 EVT---DPRRVSQKADVFSFGVLLLELLTGKAPSQSALNDEGVDLPRWVQSVVRSEWTSE 380 EV D S ++DV+S+G++L EL+ G+ P N + + + V R + + Sbjct: 190 EVIRMQDDNPFSFQSDVYSYGIVLYELMAGELPYAHINNRDQI-----IFMVGRGYASPD 244 Query: 379 VFDMELLRNQSSEEQMVQLLQLAIDCVAQVPDARPTMSHVVVRIE 245 + L +N + +L DCV +V + RP ++ IE Sbjct: 245 L--SRLYKNCPK-----AIKRLVADCVKKVKEERPLFPQILSSIE 282
>SRMS_HUMAN (Q9H3Y6) Tyrosine-protein kinase Srms (EC 2.7.10.2)| Length = 488 Score = 52.8 bits (125), Expect = 1e-06 Identities = 36/100 (36%), Positives = 53/100 (53%), Gaps = 12/100 (12%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATG----YRAPEVTDPRRVSQKA 515 H ++ + N+L+ +V+D GLA L+ PS ++ + APE + R SQK+ Sbjct: 348 HRDLAARNVLVDDGLACKVADFGLARLLKDDIYSPSSSSKIPVKWTAPEAANYRVFSQKS 407 Query: 514 DVFSFGVLLLELLT-GKAPSQSALNDE-------GVDLPR 419 DV+SFGVLL E+ T G+ P + N E G LPR Sbjct: 408 DVWSFGVLLHEVFTYGQCPYEGMTNHETLQQIMRGYRLPR 447
>TEC_HUMAN (P42680) Tyrosine-protein kinase Tec (EC 2.7.10.2)| Length = 631 Score = 52.8 bits (125), Expect = 1e-06 Identities = 45/157 (28%), Positives = 77/157 (49%), Gaps = 5/157 (3%) Frame = -1 Query: 694 SSTSHGNIKSSNILLSKAYQARVSDNGLATLV----GSSSSGPSRATGYRAPEVTDPRRV 527 +S H ++ + N L+S+A +VSD G+A +SSSG + PEV + R Sbjct: 483 NSFIHRDLAARNCLVSEAGVVKVSDFGMARYFLDDQYTSSSGAKFPVKWCPPEVFNYSRF 542 Query: 526 SQKADVFSFGVLLLELLT-GKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFDMELLRNQ 350 S K+DV+SFGVL+ E+ T G+ P + N E V + V R ++ +L N Sbjct: 543 SSKSDVWSFGVLMWEVFTEGRMPFEKYTNYEVVTM------VTRGH---RLYQPKLASN- 592 Query: 349 SSEEQMVQLLQLAIDCVAQVPDARPTMSHVVVRIEEI 239 + ++ + C + P+ RP+ ++ I+E+ Sbjct: 593 -------YVYEVMLRCWQEKPEGRPSFEDLLRTIDEL 622
>LCK_SAISC (Q95KR7) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) Length = 508 Score = 52.8 bits (125), Expect = 1e-06 Identities = 39/152 (25%), Positives = 75/152 (49%), Gaps = 5/152 (3%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSS----SGPSRATGYRAPEVTDPRRVSQKA 515 H +++++NIL+S +++D GLA L+ + G + APE + + K+ Sbjct: 361 HRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKS 420 Query: 514 DVFSFGVLLLELLT-GKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFDMELLRNQSSEE 338 DV+SFG+L+ E++T G+ P N P +Q++ R + R + E Sbjct: 421 DVWSFGILMTEIVTHGRIPYPGMTN------PEVIQNLERG--------YRMPRPDNCPE 466 Query: 337 QMVQLLQLAIDCVAQVPDARPTMSHVVVRIEE 242 ++ +L+ + C + PD RPT ++ +E+ Sbjct: 467 ELYKLM---MQCWRERPDDRPTFDYLRSVLED 495
>ANPRA_RAT (P18910) Atrial natriuretic peptide receptor A precursor (ANP-A)| (ANPRA) (GC-A) (Guanylate cyclase) (EC 4.6.1.2) (NPR-A) (Atrial natriuretic peptide A-type receptor) Length = 1057 Score = 52.8 bits (125), Expect = 1e-06 Identities = 49/156 (31%), Positives = 72/156 (46%), Gaps = 14/156 (8%) Frame = -1 Query: 685 SHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATG--------YRAPEV----T 542 SHGN+KSSN ++ + +++D GL S P G + APE+ + Sbjct: 653 SHGNLKSSNCVVDGRFVLKITDYGL-----ESFRDPEPEQGHTLFAKKLWTAPELLRMAS 707 Query: 541 DPRRVSQKADVFSFGVLLLELLTGKAPSQSALNDEGVDL--PRWVQSVVRSEWTSEVFDM 368 P R SQ DV+SFG++L E+ A EG+DL ++ V R E M Sbjct: 708 PPARGSQAGDVYSFGIILQEI----ALRSGVFYVEGLDLSPKEIIERVTRGEQPPFRPSM 763 Query: 367 ELLRNQSSEEQMVQLLQLAIDCVAQVPDARPTMSHV 260 +L QS E++ QL+Q C A+ P RP + Sbjct: 764 DL---QSHLEELGQLMQ---RCWAEDPQERPPFQQI 793
>ANPRA_MOUSE (P18293) Atrial natriuretic peptide receptor A precursor (ANP-A)| (ANPRA) (GC-A) (Guanylate cyclase) (EC 4.6.1.2) (NPR-A) (Atrial natriuretic peptide A-type receptor) Length = 1057 Score = 52.8 bits (125), Expect = 1e-06 Identities = 49/156 (31%), Positives = 72/156 (46%), Gaps = 14/156 (8%) Frame = -1 Query: 685 SHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATG--------YRAPEV----T 542 SHGN+KSSN ++ + +++D GL S P G + APE+ + Sbjct: 653 SHGNLKSSNCVVDGRFVLKITDYGL-----ESFRDPEPEQGHTLFAKKLWTAPELLRMAS 707 Query: 541 DPRRVSQKADVFSFGVLLLELLTGKAPSQSALNDEGVDL--PRWVQSVVRSEWTSEVFDM 368 P R SQ DV+SFG++L E+ A EG+DL ++ V R E M Sbjct: 708 PPARGSQAGDVYSFGIILQEI----ALRSGVFYVEGLDLSPKEIIERVTRGEQPPFRPSM 763 Query: 367 ELLRNQSSEEQMVQLLQLAIDCVAQVPDARPTMSHV 260 +L QS E++ QL+Q C A+ P RP + Sbjct: 764 DL---QSHLEELGQLMQ---RCWAEDPQERPPFQQI 793
>RIPK2_HUMAN (O43353) Receptor-interacting serine/threonine-protein kinase 2 (EC| 2.7.11.1) (RIP-like-interacting CLARP kinase) (Receptor-interacting protein 2) (RIP-2) (CARD-containing interleukin-1 beta-converting enzyme-associated kinase) (CARD-containi Length = 540 Score = 52.8 bits (125), Expect = 1e-06 Identities = 43/169 (25%), Positives = 76/169 (44%), Gaps = 11/169 (6%) Frame = -1 Query: 712 YIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLA-------TLVGSSSSGPSRAT-GYR 557 Y+H+ + H ++K+ NILL + +++D GL+ + SS S P T Y Sbjct: 134 YLHNMTPPLLHHDLKTQNILLDNEFHVKIADFGLSKWRMMSLSQSRSSKSAPEGGTIIYM 193 Query: 556 APEVTDP---RRVSQKADVFSFGVLLLELLTGKAPSQSALNDEGVDLPRWVQSVVRSEWT 386 PE +P R S K D++S+ V+ E+L+ K P + N P + V Sbjct: 194 PPENYEPGQKSRASIKHDIYSYAVITWEVLSRKQPFEDVTN------PLQIMYSVSQGHR 247 Query: 385 SEVFDMELLRNQSSEEQMVQLLQLAIDCVAQVPDARPTMSHVVVRIEEI 239 + + L + +M+ L++ AQ PD RP+ ++ +E + Sbjct: 248 PVINEESLPYDIPHRARMISLIESG---WAQNPDERPSFLKCLIELEPV 293
>GPRK2_DROME (P32866) G protein-coupled receptor kinase 2 (EC 2.7.11.16)| Length = 714 Score = 52.8 bits (125), Expect = 1e-06 Identities = 32/84 (38%), Positives = 41/84 (48%), Gaps = 2/84 (2%) Frame = -1 Query: 706 HSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLV--GSSSSGPSRATGYRAPEVTDPR 533 H + + K NILL R+SD GLA + G G GY APEV D Sbjct: 425 HLHKQGIVYRDCKPENILLDDHGHVRISDLGLAVEIPEGEMVRGRVGTVGYMAPEVIDNE 484 Query: 532 RVSQKADVFSFGVLLLELLTGKAP 461 + + D FSFG LL E++ G+AP Sbjct: 485 KYAFSPDWFSFGCLLYEMIEGQAP 508
>NRKA_TRYBB (Q08942) Putative serine/threonine-protein kinase A (EC 2.7.11.1)| Length = 431 Score = 52.4 bits (124), Expect = 1e-06 Identities = 37/100 (37%), Positives = 57/100 (57%), Gaps = 5/100 (5%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATG-----YRAP 551 +YIHS H +IKS+N+LL+ ++ D G + + SG +T Y AP Sbjct: 136 DYIHS--HKMLHRDIKSANVLLTSTGLVKLGDFGFSHQYEDTVSGVVASTFCGTPYYLAP 193 Query: 550 EVTDPRRVSQKADVFSFGVLLLELLTGKAPSQSALNDEGV 431 E+ + +R ++KADV+S GVLL E++ K P SA N +G+ Sbjct: 194 ELWNNKRYNKKADVWSLGVLLYEIMGMKKPF-SASNLKGL 232
>BRAF1_CHICK (Q04982) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Rmil serine/threonine-protein kinase) (c-Rmil) Length = 806 Score = 52.4 bits (124), Expect = 1e-06 Identities = 45/165 (27%), Positives = 82/165 (49%), Gaps = 8/165 (4%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVG--SSSSGPSRATG---YRAP 551 +Y+H+ S H ++KS+NI L + ++ D GLAT+ S S + +G + AP Sbjct: 605 DYLHA--KSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAP 662 Query: 550 EVT---DPRRVSQKADVFSFGVLLLELLTGKAPSQSALNDEGVDLPRWVQSVVRSEWTSE 380 EV D S ++DV++FG++L EL+TG+ P + N + + + V R + Sbjct: 663 EVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQI-----IFMVGRGYLSP- 716 Query: 379 VFDMELLRNQSSEEQMVQLLQLAIDCVAQVPDARPTMSHVVVRIE 245 D+ +R+ + + +L +C+ + D RP ++ IE Sbjct: 717 --DLSKVRSNCPK----AMKRLMAECLKKKRDERPLFPQILASIE 755
>RIPK2_MOUSE (P58801) Receptor-interacting serine/threonine-protein kinase 2 (EC| 2.7.11.1) Length = 539 Score = 52.4 bits (124), Expect = 1e-06 Identities = 43/169 (25%), Positives = 75/169 (44%), Gaps = 11/169 (6%) Frame = -1 Query: 712 YIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLA----TLVGSSSSGPSRATG----YR 557 Y+H+ + H ++K+ NILL + +++D GL+ + S S S G Y Sbjct: 134 YLHNMNPPLLHHDLKTQNILLDNEFHVKIADFGLSKWRMMSLSQSRSYKSAPEGGTIIYM 193 Query: 556 APEVTDP---RRVSQKADVFSFGVLLLELLTGKAPSQSALNDEGVDLPRWVQSVVRSEWT 386 PE +P R S K D++S+ V++ E+L+ K P + N P + V Sbjct: 194 PPENYEPGQKSRASVKHDIYSYAVIMWEVLSRKQPFEEVTN------PLQIMYSVSQGHR 247 Query: 385 SEVFDMELLRNQSSEEQMVQLLQLAIDCVAQVPDARPTMSHVVVRIEEI 239 + + L + M+ L+Q AQ PD RP+ ++ +E + Sbjct: 248 PDTSEENLPFDIPHRGLMISLIQSG---WAQNPDERPSFLKCLIELEPV 293
>BRAF1_HUMAN (P15056) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (p94) (v-Raf murine sarcoma viral oncogene homolog B1) Length = 766 Score = 52.4 bits (124), Expect = 1e-06 Identities = 45/165 (27%), Positives = 82/165 (49%), Gaps = 8/165 (4%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVG--SSSSGPSRATG---YRAP 551 +Y+H+ S H ++KS+NI L + ++ D GLAT+ S S + +G + AP Sbjct: 565 DYLHA--KSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAP 622 Query: 550 EVT---DPRRVSQKADVFSFGVLLLELLTGKAPSQSALNDEGVDLPRWVQSVVRSEWTSE 380 EV D S ++DV++FG++L EL+TG+ P + N + + + V R + Sbjct: 623 EVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQI-----IFMVGRGYLSP- 676 Query: 379 VFDMELLRNQSSEEQMVQLLQLAIDCVAQVPDARPTMSHVVVRIE 245 D+ +R+ + + +L +C+ + D RP ++ IE Sbjct: 677 --DLSKVRSNCPK----AMKRLMAECLKKKRDERPLFPQILASIE 715
>RMIL_AVEVR (P27966) Serine/threonine-protein kinase transforming protein Rmil| (EC 2.7.11.1) Length = 450 Score = 52.4 bits (124), Expect = 1e-06 Identities = 45/165 (27%), Positives = 82/165 (49%), Gaps = 8/165 (4%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVG--SSSSGPSRATG---YRAP 551 +Y+H+ S H ++KS+NI L + ++ D GLAT+ S S + +G + AP Sbjct: 191 DYLHA--KSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAP 248 Query: 550 EVT---DPRRVSQKADVFSFGVLLLELLTGKAPSQSALNDEGVDLPRWVQSVVRSEWTSE 380 EV D S ++DV++FG++L EL+TG+ P + N + + + V R + Sbjct: 249 EVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQI-----IFMVGRGYLSP- 302 Query: 379 VFDMELLRNQSSEEQMVQLLQLAIDCVAQVPDARPTMSHVVVRIE 245 D+ +R+ + + +L +C+ + D RP ++ IE Sbjct: 303 --DLSKVRSNCPK----AMKRLMAECLKKKRDERPLFPQILASIE 341
>BRAF1_COTJA (P34908) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (RMIL serine/threonine-protein kinase) (c-RMIL) Length = 807 Score = 52.4 bits (124), Expect = 1e-06 Identities = 45/165 (27%), Positives = 82/165 (49%), Gaps = 8/165 (4%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVG--SSSSGPSRATG---YRAP 551 +Y+H+ S H ++KS+NI L + ++ D GLAT+ S S + +G + AP Sbjct: 605 DYLHA--KSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAP 662 Query: 550 EVT---DPRRVSQKADVFSFGVLLLELLTGKAPSQSALNDEGVDLPRWVQSVVRSEWTSE 380 EV D S ++DV++FG++L EL+TG+ P + N + + + V R + Sbjct: 663 EVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQI-----IFMVGRGYLSP- 716 Query: 379 VFDMELLRNQSSEEQMVQLLQLAIDCVAQVPDARPTMSHVVVRIE 245 D+ +R+ + + +L +C+ + D RP ++ IE Sbjct: 717 --DLSKVRSNCPK----AMKRLMAECLKKKRDERPLFPQILASIE 755
>RMIL_AVII1 (P10533) Serine/threonine-protein kinase transforming protein Rmil| (EC 2.7.11.1) Length = 367 Score = 52.4 bits (124), Expect = 1e-06 Identities = 45/165 (27%), Positives = 82/165 (49%), Gaps = 8/165 (4%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVG--SSSSGPSRATG---YRAP 551 +Y+H+ S H ++KS+NI L + ++ D GLAT+ S S + +G + AP Sbjct: 175 DYLHA--KSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAP 232 Query: 550 EVT---DPRRVSQKADVFSFGVLLLELLTGKAPSQSALNDEGVDLPRWVQSVVRSEWTSE 380 EV D S ++DV++FG++L EL+TG+ P + N + + + V R + Sbjct: 233 EVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQI-----IFMVGRGYLSP- 286 Query: 379 VFDMELLRNQSSEEQMVQLLQLAIDCVAQVPDARPTMSHVVVRIE 245 D+ +R+ + + +L +C+ + D RP ++ IE Sbjct: 287 --DLSKVRSNCPK----AMKRLMAECLKKKRDERPLFPQILASIE 325
>BRAF1_MOUSE (P28028) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Fragment) Length = 328 Score = 52.4 bits (124), Expect = 1e-06 Identities = 45/165 (27%), Positives = 82/165 (49%), Gaps = 8/165 (4%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVG--SSSSGPSRATG---YRAP 551 +Y+H+ S H ++KS+NI L + ++ D GLAT+ S S + +G + AP Sbjct: 127 DYLHA--KSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAP 184 Query: 550 EVT---DPRRVSQKADVFSFGVLLLELLTGKAPSQSALNDEGVDLPRWVQSVVRSEWTSE 380 EV D S ++DV++FG++L EL+TG+ P + N + + + V R + Sbjct: 185 EVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQI-----IFMVGRGYLSP- 238 Query: 379 VFDMELLRNQSSEEQMVQLLQLAIDCVAQVPDARPTMSHVVVRIE 245 D+ +R+ + + +L +C+ + D RP ++ IE Sbjct: 239 --DLSKVRSNCPK----AMKRLMAECLKKKRDERPLFPQILASIE 277
>M3K12_RAT (Q63796) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 888 Score = 52.0 bits (123), Expect = 2e-06 Identities = 30/76 (39%), Positives = 46/76 (60%), Gaps = 2/76 (2%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRA--TGYRAPEVTDPRRVSQKADV 509 H ++KS N+L++ ++SD G + + S+ S A + APEV VS+K D+ Sbjct: 267 HRDLKSPNMLITYDDVVKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDI 326 Query: 508 FSFGVLLLELLTGKAP 461 +SFGV+L ELLTG+ P Sbjct: 327 WSFGVVLWELLTGEIP 342
>M3K12_MOUSE (Q60700) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 888 Score = 52.0 bits (123), Expect = 2e-06 Identities = 30/76 (39%), Positives = 46/76 (60%), Gaps = 2/76 (2%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRA--TGYRAPEVTDPRRVSQKADV 509 H ++KS N+L++ ++SD G + + S+ S A + APEV VS+K D+ Sbjct: 267 HRDLKSPNMLITYDDVVKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDI 326 Query: 508 FSFGVLLLELLTGKAP 461 +SFGV+L ELLTG+ P Sbjct: 327 WSFGVVLWELLTGEIP 342
>TOPK_HUMAN (Q96KB5) T-lymphokine-activated killer cell-originated protein| kinase (EC 2.7.12.2) (T-LAK cell-originated protein kinase) (PDZ-binding kinase) (Spermatogenesis-related protein kinase) (SPK) (MAPKK-like protein kinase) (Nori-3) Length = 322 Score = 52.0 bits (123), Expect = 2e-06 Identities = 37/166 (22%), Positives = 80/166 (48%), Gaps = 9/166 (5%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQA-RVSDNGLATLVGSSSSGPSRATGYRAPEVTD 539 +Y+H HG+IKSSN+++ ++ ++ D G++ + + + Y E Sbjct: 155 KYLHQ-EKKLLHGDIKSSNVVIKGDFETIKICDVGVSLPLDENMTVTDPEACYIGTEPWK 213 Query: 538 PRR-------VSQKADVFSFGVLLLELLTGKAPSQSALNDEGVDLPRWVQSVVRSE-WTS 383 P+ ++ KAD+F+FG+ L E++T P + ND+ + + +S E + + Sbjct: 214 PKEAVEENGVITDKADIFAFGLTLWEMMTLSIPHINLSNDDDDEDKTFDESDFDDEAYYA 273 Query: 382 EVFDMELLRNQSSEEQMVQLLQLAIDCVAQVPDARPTMSHVVVRIE 245 + + + +E ++++L C + P RP+ +H+V +E Sbjct: 274 ALGTRPPINMEELDESYQKVIELFSVCTNEDPKDRPSAAHIVEALE 319
>MK14B_DROME (O61443) Mitogen-activated protein kinase 14B (EC 2.7.11.24) (MAP| kinase p38b) (D-p38b) Length = 365 Score = 52.0 bits (123), Expect = 2e-06 Identities = 31/84 (36%), Positives = 49/84 (58%), Gaps = 1/84 (1%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATGYRAPEV-TD 539 +YIHS + H ++K SNI +++ + R+ D GLA S +G YRAPE+ + Sbjct: 142 KYIHS--AGVIHRDLKPSNIAVNEDCELRILDFGLARPAESEMTGYVATRWYRAPEIMLN 199 Query: 538 PRRVSQKADVFSFGVLLLELLTGK 467 +Q AD++S G ++ ELLTG+ Sbjct: 200 WMHYNQTADIWSVGCIMAELLTGR 223
>M3K12_HUMAN (Q12852) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 859 Score = 52.0 bits (123), Expect = 2e-06 Identities = 30/76 (39%), Positives = 46/76 (60%), Gaps = 2/76 (2%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRA--TGYRAPEVTDPRRVSQKADV 509 H ++KS N+L++ ++SD G + + S+ S A + APEV VS+K D+ Sbjct: 234 HRDLKSPNMLITYDDVVKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDI 293 Query: 508 FSFGVLLLELLTGKAP 461 +SFGV+L ELLTG+ P Sbjct: 294 WSFGVVLWELLTGEIP 309
>FYN_HUMAN (P06241) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) (Protooncogene Syn) (SLK) Length = 536 Score = 51.6 bits (122), Expect = 2e-06 Identities = 42/152 (27%), Positives = 71/152 (46%), Gaps = 5/152 (3%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSS----SGPSRATGYRAPEVTDPRRVSQKA 515 H +++S+NIL+ +++D GLA L+ + G + APE R + K+ Sbjct: 387 HRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS 446 Query: 514 DVFSFGVLLLELLT-GKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFDMELLRNQSSEE 338 DV+SFG+LL EL+T G+ P N E ++ V R R ++ Sbjct: 447 DVWSFGILLTELVTKGRVPYPGMNNRE------VLEQVERG-----------YRMPCPQD 489 Query: 337 QMVQLLQLAIDCVAQVPDARPTMSHVVVRIEE 242 + L +L I C + P+ RPT ++ +E+ Sbjct: 490 CPISLHELMIHCWKKDPEERPTFEYLQSFLED 521
>NEK9_HUMAN (Q8TD19) Serine/threonine-protein kinase Nek9 (EC 2.7.11.1)| (NimA-related protein kinase 9) (Never in mitosis A-related kinase 9) (Nercc1 kinase) (NIMA-related kinase 8) (Nek8) Length = 979 Score = 51.2 bits (121), Expect = 3e-06 Identities = 42/147 (28%), Positives = 71/147 (48%), Gaps = 3/147 (2%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATG---YRAPEVTDPRRVSQKAD 512 H +IK+ NI L+KA ++ D GLA + S S G Y +PE+ + + K+D Sbjct: 174 HRDIKTLNIFLTKANLIKLGDYGLAKKLNSEYSMAETLVGTPYYMSPELCQGVKYNFKSD 233 Query: 511 VFSFGVLLLELLTGKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFDMELLRNQSSEEQM 332 +++ G ++ ELLT K + A N + + + VQ + E S + +E Sbjct: 234 IWAVGCVIFELLTLKR-TFDATNPLNLCV-KIVQGIRAMEVDSSQYSLE----------- 280 Query: 331 VQLLQLAIDCVAQVPDARPTMSHVVVR 251 L+Q+ C+ Q P+ RPT ++ R Sbjct: 281 --LIQMVHSCLDQDPEQRPTADELLDR 305
>FYN_MOUSE (P39688) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 533 Score = 51.2 bits (121), Expect = 3e-06 Identities = 42/152 (27%), Positives = 71/152 (46%), Gaps = 5/152 (3%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSS----SGPSRATGYRAPEVTDPRRVSQKA 515 H +++S+NIL+ +++D GLA L+ + G + APE R + K+ Sbjct: 384 HRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS 443 Query: 514 DVFSFGVLLLELLT-GKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFDMELLRNQSSEE 338 DV+SFG+LL EL+T G+ P N E ++ V R R ++ Sbjct: 444 DVWSFGILLTELVTKGRVPYPGMNNRE------VLEQVERG-----------YRMPCPQD 486 Query: 337 QMVQLLQLAIDCVAQVPDARPTMSHVVVRIEE 242 + L +L I C + P+ RPT ++ +E+ Sbjct: 487 CPISLHELMIHCWKKDPEERPTFEYLQGFLED 518
>FYN_CHICK (Q05876) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 533 Score = 51.2 bits (121), Expect = 3e-06 Identities = 42/152 (27%), Positives = 71/152 (46%), Gaps = 5/152 (3%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSS----SGPSRATGYRAPEVTDPRRVSQKA 515 H +++S+NIL+ +++D GLA L+ + G + APE R + K+ Sbjct: 384 HRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS 443 Query: 514 DVFSFGVLLLELLT-GKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFDMELLRNQSSEE 338 DV+SFG+LL EL+T G+ P N E ++ V R R ++ Sbjct: 444 DVWSFGILLTELVTKGRVPYPGMNNRE------VLEQVERG-----------YRMPCPQD 486 Query: 337 QMVQLLQLAIDCVAQVPDARPTMSHVVVRIEE 242 + L +L I C + P+ RPT ++ +E+ Sbjct: 487 CPISLHELMIHCWKKDPEERPTFEYLQGFLED 518
>FYN_XENLA (P13406) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 536 Score = 51.2 bits (121), Expect = 3e-06 Identities = 41/152 (26%), Positives = 72/152 (47%), Gaps = 5/152 (3%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSS----SGPSRATGYRAPEVTDPRRVSQKA 515 H +++S+NIL+ +++D GLA L+ + G + APE R + K+ Sbjct: 387 HRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS 446 Query: 514 DVFSFGVLLLELLT-GKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFDMELLRNQSSEE 338 DV+SFG+LL EL+T G+ P N E ++ V R R ++ Sbjct: 447 DVWSFGILLTELVTKGRVPYPGMNNRE------VLEQVERG-----------YRMPCPQD 489 Query: 337 QMVQLLQLAIDCVAQVPDARPTMSHVVVRIEE 242 + L +L ++C + P+ RPT ++ +E+ Sbjct: 490 CPISLHELMLNCWKKDPEERPTFEYLQGFLED 521
>MIL_AVIMH (P00531) Serine/threonine-protein kinase transforming protein mil| (EC 2.7.11.1) Length = 380 Score = 51.2 bits (121), Expect = 3e-06 Identities = 45/164 (27%), Positives = 80/164 (48%), Gaps = 8/164 (4%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVG--SSSSGPSRATG---YRAP 551 +Y+H+ + H ++KS+NI L ++ D GLAT+ S S + TG + AP Sbjct: 190 DYLHA--KNIIHRDMKSNNIFLHGGLTVKIGDFGLATVKSRWSGSQQVEQPTGSILWMAP 247 Query: 550 EVT---DPRRVSQKADVFSFGVLLLELLTGKAPSQSALNDEGVDLPRWVQSVVRSEWTSE 380 EV D S ++DV+S+G++L EL+TG+ P N + + + V R + + Sbjct: 248 EVIRMQDSNPFSFQSDVYSYGIVLYELMTGELPYSHINNRDQI-----IFMVGRGYASPD 302 Query: 379 VFDMELLRNQSSEEQMVQLLQLAIDCVAQVPDARPTMSHVVVRI 248 + +L +N + +L DC+ +V + RP ++ I Sbjct: 303 L--SKLYKNCPK-----AMKRLVADCLKKVREERPLFPQILSSI 339
>NRKB_TRYBB (Q03428) Putative serine/threonine-protein kinase B (EC 2.7.11.1)| Length = 431 Score = 50.8 bits (120), Expect = 4e-06 Identities = 37/100 (37%), Positives = 56/100 (56%), Gaps = 5/100 (5%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATG-----YRAP 551 +YIHS H +IKS+N+LL+ ++ D G + + SG +T Y AP Sbjct: 136 DYIHS--HKMLHRDIKSANVLLTSTGLVKLGDFGFSHQYEDTVSGVVASTFCGTPYYLAP 193 Query: 550 EVTDPRRVSQKADVFSFGVLLLELLTGKAPSQSALNDEGV 431 E+ + R ++KADV+S GVLL E++ K P SA N +G+ Sbjct: 194 ELWNNLRYNKKADVWSLGVLLYEIMGMKKPF-SASNLKGL 232
>ARAF_PIG (O19004) A-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (A-Raf-1) Length = 606 Score = 50.8 bits (120), Expect = 4e-06 Identities = 32/93 (34%), Positives = 52/93 (55%), Gaps = 8/93 (8%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSG-----PSRATGYRAP 551 +Y+H+ + H ++KS+NI L + ++ D GLAT+ S PS + + A Sbjct: 418 DYLHA--KNIIHRDLKSNNIFLHEGLTVKIGDFGLATVKTRWSGAQPLEQPSGSVLWMAA 475 Query: 550 EVT---DPRRVSQKADVFSFGVLLLELLTGKAP 461 EV DP S ++DV+++GV+L EL+TG P Sbjct: 476 EVIRMQDPNPYSFQSDVYAYGVVLYELMTGSLP 508
>ARAF_HUMAN (P10398) A-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (A-raf-1) (Proto-oncogene Pks) Length = 606 Score = 50.8 bits (120), Expect = 4e-06 Identities = 32/93 (34%), Positives = 52/93 (55%), Gaps = 8/93 (8%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSG-----PSRATGYRAP 551 +Y+H+ + H ++KS+NI L + ++ D GLAT+ S PS + + A Sbjct: 418 DYLHA--KNIIHRDLKSNNIFLHEGLTVKIGDFGLATVKTRWSGAQPLEQPSGSVLWMAA 475 Query: 550 EVT---DPRRVSQKADVFSFGVLLLELLTGKAP 461 EV DP S ++DV+++GV+L EL+TG P Sbjct: 476 EVIRMQDPNPYSFQSDVYAYGVVLYELMTGSLP 508
>FGR_MOUSE (P14234) Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2)| (P55-FGR) (C-FGR) Length = 517 Score = 50.8 bits (120), Expect = 4e-06 Identities = 30/87 (34%), Positives = 50/87 (57%), Gaps = 5/87 (5%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATGY----RAPEVTDPRRVSQKA 515 H +++++NIL+ + +++D GLA L+ + P + T + APE R + K+ Sbjct: 368 HRDLRAANILVGEYLICKIADFGLARLIEDNEYNPQQGTKFPIKWTAPEAALFGRFTVKS 427 Query: 514 DVFSFGVLLLELLT-GKAPSQSALNDE 437 DV+SFG+LL EL+T G+ P N E Sbjct: 428 DVWSFGILLTELITKGRVPYPGMNNRE 454
>ARAF_RAT (P14056) A-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) Length = 604 Score = 50.8 bits (120), Expect = 4e-06 Identities = 32/93 (34%), Positives = 52/93 (55%), Gaps = 8/93 (8%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSG-----PSRATGYRAP 551 +Y+H+ + H ++KS+NI L + ++ D GLAT+ S PS + + A Sbjct: 416 DYLHA--KNIIHRDLKSNNIFLHEGLTVKIGDFGLATVKTRWSGAQPLEQPSGSVLWMAA 473 Query: 550 EVT---DPRRVSQKADVFSFGVLLLELLTGKAP 461 EV DP S ++DV+++GV+L EL+TG P Sbjct: 474 EVIRMQDPNPYSFQSDVYAYGVVLYELMTGSLP 506
>ARAF_MOUSE (P04627) A-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) Length = 604 Score = 50.8 bits (120), Expect = 4e-06 Identities = 32/93 (34%), Positives = 52/93 (55%), Gaps = 8/93 (8%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSG-----PSRATGYRAP 551 +Y+H+ + H ++KS+NI L + ++ D GLAT+ S PS + + A Sbjct: 416 DYLHA--KNIIHRDLKSNNIFLHEGLTVKIGDFGLATVKTRWSGAQPLEQPSGSVLWMAA 473 Query: 550 EVT---DPRRVSQKADVFSFGVLLLELLTGKAP 461 EV DP S ++DV+++GV+L EL+TG P Sbjct: 474 EVIRMQDPNPYSFQSDVYAYGVVLYELMTGSLP 506
>BLK_HUMAN (P51451) Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte| kinase) (p55-BLK) Length = 504 Score = 50.8 bits (120), Expect = 4e-06 Identities = 31/86 (36%), Positives = 51/86 (59%), Gaps = 4/86 (4%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGS---SSSGPSRATGYRAPEVTDPRRVSQKAD 512 H +++++NIL+S+A +++D GLA ++ S + G + APE + KAD Sbjct: 357 HRDLRAANILVSEALCCKIADFGLARIIDSEYTAQEGAKFPIKWTAPEAIHFGVFTIKAD 416 Query: 511 VFSFGVLLLELLT-GKAPSQSALNDE 437 V+SFGVLL+E++T G+ P N E Sbjct: 417 VWSFGVLLMEVVTYGRVPYPGMSNPE 442
>YES_AVISY (P00527) Tyrosine-protein kinase transforming protein YES (EC| 2.7.10.2) (Fragment) Length = 528 Score = 50.4 bits (119), Expect = 5e-06 Identities = 42/152 (27%), Positives = 73/152 (48%), Gaps = 5/152 (3%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSS----SGPSRATGYRAPEVTDPRRVSQKA 515 H +++++NIL+ +++D GLA L+ + G + APE R + K+ Sbjct: 384 HRDLRAANILVGDNLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS 443 Query: 514 DVFSFGVLLLELLT-GKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFDMELLRNQSSEE 338 DV+SFG+LL EL+T G+ P +N E ++ V R + Q E Sbjct: 444 DVWSFGILLTELVTKGRVPYPGMVNRE------VLEQVERG--------YRMPCPQGCPE 489 Query: 337 QMVQLLQLAIDCVAQVPDARPTMSHVVVRIEE 242 + +L++L C + PD RPT ++ +E+ Sbjct: 490 SLHELMKL---CWKKDPDERPTFEYIQSFLED 518
>E2AK2_MOUSE (Q03963) Interferon-induced, double-stranded RNA-activated protein| kinase (EC 2.7.11.1) (Interferon-inducible RNA-dependent protein kinase) (Protein kinase RNA-activated) (PKR) (p68 kinase) (P1/eIF-2A protein kinase) (Serine/threonine-protein Length = 515 Score = 50.4 bits (119), Expect = 5e-06 Identities = 38/161 (23%), Positives = 76/161 (47%), Gaps = 3/161 (1%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATG---YRAPEV 545 EYIHS H ++K NI L ++ D GLAT + + +R TG Y +PE Sbjct: 365 EYIHS--KGLIHRDLKPGNIFLVDERHIKIGDFGLATALENDGKSRTRRTGTLQYMSPEQ 422 Query: 544 TDPRRVSQKADVFSFGVLLLELLTGKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFDME 365 + ++ D+F+ G++L ELL + ++ +S+ + ++++++FD Sbjct: 423 LFLKHYGKEVDIFALGLILAELLHTCFTESEKI--------KFFESLRKGDFSNDIFD-- 472 Query: 364 LLRNQSSEEQMVQLLQLAIDCVAQVPDARPTMSHVVVRIEE 242 + E+ +++ L +++ P RP S ++ + E Sbjct: 473 -----NKEKSLLKKL------LSEKPKDRPETSEILKTLAE 502
>GUC2C_HUMAN (P25092) Heat-stable enterotoxin receptor precursor (GC-C)| (Intestinal guanylate cyclase) (EC 4.6.1.2) (STA receptor) (hSTAR) Length = 1073 Score = 50.4 bits (119), Expect = 5e-06 Identities = 35/159 (22%), Positives = 76/159 (47%), Gaps = 1/159 (0%) Frame = -1 Query: 712 YIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATGYRAPEVTDPR 533 Y+HS+ + HG +KS+N ++ +++D G +++ P + + APE Sbjct: 603 YLHSSKTEV-HGRLKSTNCVVDSRMVVKITDFGCNSIL------PPKKDLWTAPEHLRQA 655 Query: 532 RVSQKADVFSFGVLLLELLTGKAPSQS-ALNDEGVDLPRWVQSVVRSEWTSEVFDMELLR 356 +SQK DV+S+G++ E++ K + + D + R S + ++F Sbjct: 656 NISQKGDVYSYGIIAQEIILRKETFYTLSCRDRNEKIFRVENSNGMKPFRPDLF------ 709 Query: 355 NQSSEEQMVQLLQLAIDCVAQVPDARPTMSHVVVRIEEI 239 +++EE+ +++ L +C + P+ RP + + +I Sbjct: 710 LETAEEKELEVYLLVKNCWEEDPEKRPDFKKIETTLAKI 748
>YES_CHICK (P09324) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 540 Score = 50.4 bits (119), Expect = 5e-06 Identities = 42/152 (27%), Positives = 73/152 (48%), Gaps = 5/152 (3%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSS----SGPSRATGYRAPEVTDPRRVSQKA 515 H +++++NIL+ +++D GLA L+ + G + APE R + K+ Sbjct: 391 HRDLRAANILVGDNLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS 450 Query: 514 DVFSFGVLLLELLT-GKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFDMELLRNQSSEE 338 DV+SFG+LL EL+T G+ P +N E ++ V R + Q E Sbjct: 451 DVWSFGILLTELVTKGRVPYPGMVNRE------VLEQVERG--------YRMPCPQGCPE 496 Query: 337 QMVQLLQLAIDCVAQVPDARPTMSHVVVRIEE 242 + +L++L C + PD RPT ++ +E+ Sbjct: 497 SLHELMKL---CWKKDPDERPTFEYIQSFLED 525
>PKN2_BACSU (O34507) Probable serine/threonine-protein kinase yloP (EC| 2.7.11.1) Length = 648 Score = 50.4 bits (119), Expect = 5e-06 Identities = 35/117 (29%), Positives = 59/117 (50%), Gaps = 13/117 (11%) Frame = -1 Query: 706 HSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRAT----GYRAPEVTD 539 H+ + H +IK NIL+ +V+D G+AT + S++ + + Y +PE Sbjct: 124 HAHQNQIVHRDIKPHNILIDHMGNIKVTDFGIATALSSTTITHTNSVLGSVHYLSPEQAR 183 Query: 538 PRRVSQKADVFSFGVLLLELLTGKAP--SQSA-------LNDEGVDLPRWVQSVVRS 395 ++K+D+++ G++L ELLTG+ P +SA L E RW SV +S Sbjct: 184 GGLATKKSDIYALGIVLFELLTGRIPFDGESAVSIALKHLQAETPSAKRWNPSVPQS 240
>RAF1_XENLA (P09560) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (C-RAF) Length = 638 Score = 50.4 bits (119), Expect = 5e-06 Identities = 33/93 (35%), Positives = 54/93 (58%), Gaps = 8/93 (8%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVG--SSSSGPSRATG---YRAP 551 +Y+H+ + H ++KS+NI L + ++ D GLAT+ S S + TG + AP Sbjct: 448 DYLHA--KNIIHRDMKSNNIFLHEGLTVKIGDFGLATVKTRWSGSQQVEQLTGSILWMAP 505 Query: 550 EVT---DPRRVSQKADVFSFGVLLLELLTGKAP 461 EV D S ++DV+S+G++L EL+TG+ P Sbjct: 506 EVIRMQDNNPFSFQSDVYSYGIVLYELMTGELP 538
>FYN_XIPHE (P27446) Proto-oncogene tyrosine-protein kinase FYN (EC 2.7.10.2)| (P59-FYN) Length = 536 Score = 50.1 bits (118), Expect = 7e-06 Identities = 41/152 (26%), Positives = 70/152 (46%), Gaps = 5/152 (3%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSS----SGPSRATGYRAPEVTDPRRVSQKA 515 H +++S+NIL+ +++D GLA L+ + G + APE R + K+ Sbjct: 387 HRDLRSANILVGDNLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS 446 Query: 514 DVFSFGVLLLELLT-GKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFDMELLRNQSSEE 338 DV+SFG+LL EL+T G+ P N E ++ V R R ++ Sbjct: 447 DVWSFGILLTELVTKGRVPYPGMNNRE------VLEQVERG-----------YRMPCPQD 489 Query: 337 QMVQLLQLAIDCVAQVPDARPTMSHVVVRIEE 242 L +L + C + P+ RPT ++ +E+ Sbjct: 490 CPASLHELMLQCWKKDPEERPTFEYLQAFLED 521
>SRC_RAT (Q9WUD9) Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2)| (p60-Src) (c-Src) (pp60c-src) Length = 535 Score = 50.1 bits (118), Expect = 7e-06 Identities = 43/152 (28%), Positives = 68/152 (44%), Gaps = 5/152 (3%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSS----SGPSRATGYRAPEVTDPRRVSQKA 515 H +++++NIL+ + +V+D GLA L+ + G + APE R + K+ Sbjct: 386 HRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS 445 Query: 514 DVFSFGVLLLELLT-GKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFDMELLRNQSSEE 338 DV+SFG+LL EL T G+ P +N E +D V R R E Sbjct: 446 DVWSFGILLTELTTKGRVPYPGMVNREVLD------QVERG-----------YRMPCPPE 488 Query: 337 QMVQLLQLAIDCVAQVPDARPTMSHVVVRIEE 242 L L C + P+ RPT ++ +E+ Sbjct: 489 CPESLHDLMCQCWRKEPEERPTFEYLQAFLED 520
>SRC_HUMAN (P12931) Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2)| (p60-Src) (c-Src) (pp60c-src) Length = 535 Score = 50.1 bits (118), Expect = 7e-06 Identities = 43/152 (28%), Positives = 68/152 (44%), Gaps = 5/152 (3%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSS----SGPSRATGYRAPEVTDPRRVSQKA 515 H +++++NIL+ + +V+D GLA L+ + G + APE R + K+ Sbjct: 386 HRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS 445 Query: 514 DVFSFGVLLLELLT-GKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFDMELLRNQSSEE 338 DV+SFG+LL EL T G+ P +N E +D V R R E Sbjct: 446 DVWSFGILLTELTTKGRVPYPGMVNREVLD------QVERG-----------YRMPCPPE 488 Query: 337 QMVQLLQLAIDCVAQVPDARPTMSHVVVRIEE 242 L L C + P+ RPT ++ +E+ Sbjct: 489 CPESLHDLMCQCWRKEPEERPTFEYLQAFLED 520
>SRC_MOUSE (P05480) Neuronal proto-oncogene tyrosine-protein kinase Src (EC| 2.7.10.2) (p60-Src) (c-Src) (pp60c-src) Length = 540 Score = 50.1 bits (118), Expect = 7e-06 Identities = 43/152 (28%), Positives = 68/152 (44%), Gaps = 5/152 (3%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSS----SGPSRATGYRAPEVTDPRRVSQKA 515 H +++++NIL+ + +V+D GLA L+ + G + APE R + K+ Sbjct: 391 HRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS 450 Query: 514 DVFSFGVLLLELLT-GKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFDMELLRNQSSEE 338 DV+SFG+LL EL T G+ P +N E +D V R R E Sbjct: 451 DVWSFGILLTELTTKGRVPYPGMVNREVLD------QVERG-----------YRMPCPPE 493 Query: 337 QMVQLLQLAIDCVAQVPDARPTMSHVVVRIEE 242 L L C + P+ RPT ++ +E+ Sbjct: 494 CPESLHDLMCQCWRKEPEERPTFEYLQAFLED 525
>TNI3K_RAT (Q7TQP6) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 834 Score = 49.7 bits (117), Expect = 9e-06 Identities = 35/90 (38%), Positives = 50/90 (55%), Gaps = 5/90 (5%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGS-SSSGPSRATG---YRAPE 548 EY+HS + H ++ S NILL + A V+D G + + S ++ G + APE Sbjct: 574 EYLHSLTQPIIHRDLNSHNILLYEDGHAVVADFGESRFLQSLDEDNMTKQPGNLRWMAPE 633 Query: 547 V-TDPRRVSQKADVFSFGVLLLELLTGKAP 461 V T R + KADVFS+ + L ELLTG+ P Sbjct: 634 VFTQCTRYTIKADVFSYSLCLWELLTGEIP 663
>SRC_AVISS (P14084) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 567 Score = 49.7 bits (117), Expect = 9e-06 Identities = 43/152 (28%), Positives = 68/152 (44%), Gaps = 5/152 (3%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSS----SGPSRATGYRAPEVTDPRRVSQKA 515 H +++++NIL+ + +V+D GLA L+ + G + APE R + K+ Sbjct: 383 HRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS 442 Query: 514 DVFSFGVLLLELLT-GKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFDMELLRNQSSEE 338 DV+SFG+LL EL T G+ P +N E +D V R R E Sbjct: 443 DVWSFGILLTELTTKGRVPYPGMVNREVLD------QVERG-----------YRMPCPPE 485 Query: 337 QMVQLLQLAIDCVAQVPDARPTMSHVVVRIEE 242 L L C + P+ RPT ++ +E+ Sbjct: 486 CPESLHDLMCQCWRKDPEERPTFEYLQAFLED 517
>SRC_CHICK (P00523) Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2)| (p60-Src) (c-Src) (pp60c-src) Length = 532 Score = 49.7 bits (117), Expect = 9e-06 Identities = 43/152 (28%), Positives = 68/152 (44%), Gaps = 5/152 (3%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSS----SGPSRATGYRAPEVTDPRRVSQKA 515 H +++++NIL+ + +V+D GLA L+ + G + APE R + K+ Sbjct: 383 HRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS 442 Query: 514 DVFSFGVLLLELLT-GKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFDMELLRNQSSEE 338 DV+SFG+LL EL T G+ P +N E +D V R R E Sbjct: 443 DVWSFGILLTELTTKGRVPYPGMVNREVLD------QVERG-----------YRMPCPPE 485 Query: 337 QMVQLLQLAIDCVAQVPDARPTMSHVVVRIEE 242 L L C + P+ RPT ++ +E+ Sbjct: 486 CPESLHDLMCQCWRKDPEERPTFEYLQAFLED 517
>SRC64_DROME (P00528) Tyrosine-protein kinase Src64B (EC 2.7.10.2) (Dsrc64)| Length = 552 Score = 49.7 bits (117), Expect = 9e-06 Identities = 42/153 (27%), Positives = 72/153 (47%), Gaps = 5/153 (3%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATGY----RAPE 548 EY+ S H ++ + N+L+ + A++ D GLA ++ P + + + APE Sbjct: 393 EYLES--KQLIHRDLAARNVLIGENNVAKICDFGLARVIADDEYCPKQGSRFPVKWTAPE 450 Query: 547 VTDPRRVSQKADVFSFGVLLLELLT-GKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFD 371 + S K+DV+S+G+LL+EL T G+ P G+ ++++ R F Sbjct: 451 AIIYGKFSIKSDVWSYGILLMELFTYGQVPY------PGMHSREVIENIERG------FR 498 Query: 370 MELLRNQSSEEQMVQLLQLAIDCVAQVPDARPT 272 M N + + QLL + C VP+ RPT Sbjct: 499 MPKPTNHYFPDNIYQLL---LQCWDAVPEKRPT 528
>SRC_AVIST (P14085) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 556 Score = 49.7 bits (117), Expect = 9e-06 Identities = 43/152 (28%), Positives = 68/152 (44%), Gaps = 5/152 (3%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSS----SGPSRATGYRAPEVTDPRRVSQKA 515 H +++++NIL+ + +V+D GLA L+ + G + APE R + K+ Sbjct: 383 HRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS 442 Query: 514 DVFSFGVLLLELLT-GKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFDMELLRNQSSEE 338 DV+SFG+LL EL T G+ P +N E +D V R R E Sbjct: 443 DVWSFGILLTELTTKGRVPYPGMVNREVLD------QVERG-----------YRMPCPPE 485 Query: 337 QMVQLLQLAIDCVAQVPDARPTMSHVVVRIEE 242 L L C + P+ RPT ++ +E+ Sbjct: 486 CPESLHDLMCQCWRKDPEERPTFEYLQAFLED 517
>NEK9_XENLA (Q7ZZC8) Serine/threonine-protein kinase Nek9 (EC 2.7.11.1)| (NimA-related protein kinase 9) (XNek9) (Nercc1 kinase) Length = 944 Score = 49.7 bits (117), Expect = 9e-06 Identities = 40/147 (27%), Positives = 70/147 (47%), Gaps = 3/147 (2%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATG---YRAPEVTDPRRVSQKAD 512 H +IK+ NI L+KA ++ D GLA + S S G Y +PE+ + S K+D Sbjct: 156 HRDIKTLNIFLTKANLIKLGDYGLAKQLSSEYSMAETCVGTLYYMSPEICQGVKYSFKSD 215 Query: 511 VFSFGVLLLELLTGKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFDMELLRNQSSEEQM 332 +++ G +L ELLT + A N + + +V+ W L N +++ Sbjct: 216 IWAVGCVLYELLT-LTRTFDATNPLNLCV-----KIVQGNWAVG------LDNTVYTQEL 263 Query: 331 VQLLQLAIDCVAQVPDARPTMSHVVVR 251 ++++ C+ Q P+ RPT ++ R Sbjct: 264 IEVVHA---CLEQDPEKRPTADEILER 287
>MATK_MOUSE (P41242) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK) Length = 505 Score = 49.7 bits (117), Expect = 9e-06 Identities = 33/86 (38%), Positives = 46/86 (53%), Gaps = 1/86 (1%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATGYRAPEVTDP 536 EY+ S H ++ + NIL+S+ A+VSD GLA + APE Sbjct: 339 EYLES--KKLVHRDLAARNILVSEDLVAKVSDFGLAKAERKGLDSSRLPVKWTAPEALKN 396 Query: 535 RRVSQKADVFSFGVLLLELLT-GKAP 461 R S K+DV+SFGVLL E+ + G+AP Sbjct: 397 GRFSSKSDVWSFGVLLWEVFSYGRAP 422
>SRC_AVIS2 (P15054) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 586 Score = 49.7 bits (117), Expect = 9e-06 Identities = 43/152 (28%), Positives = 68/152 (44%), Gaps = 5/152 (3%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSS----SGPSRATGYRAPEVTDPRRVSQKA 515 H +++++NIL+ + +V+D GLA L+ + G + APE R + K+ Sbjct: 383 HRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS 442 Query: 514 DVFSFGVLLLELLT-GKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFDMELLRNQSSEE 338 DV+SFG+LL EL T G+ P +N E +D V R R E Sbjct: 443 DVWSFGILLTELTTKGRVPYPGMVNREVLD------QVERG-----------YRMPCPPE 485 Query: 337 QMVQLLQLAIDCVAQVPDARPTMSHVVVRIEE 242 L L C + P+ RPT ++ +E+ Sbjct: 486 CPESLHDLMCQCWRKDPEERPTFEYLQAFLED 517
>GUC2D_RAT (P51839) Olfactory guanylyl cyclase GC-D precursor (EC 4.6.1.2)| (Guanylate cyclase, olfactory) Length = 1110 Score = 49.7 bits (117), Expect = 9e-06 Identities = 40/164 (24%), Positives = 68/164 (41%), Gaps = 16/164 (9%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSSS-------------GPSRATGYRAPEVT 542 HG +KS N ++ + +++D+G A + S S P G R P Sbjct: 674 HGRLKSRNCVVDTRFVLKITDHGYAEFLESHCSFRPQPAPEELLWTAPELLRGPRGP--W 731 Query: 541 DPRRVSQKADVFSFGVLLLELLTGKAPSQSALNDEGVDLPRW---VQSVVRSEWTSEVFD 371 P + + K DVFS G++L E+LT P S W + ++R + Sbjct: 732 GPGKATFKGDVFSLGIILQEVLTRDPPYCS-----------WGLSAEEIIRKVASPPPLC 780 Query: 370 MELLRNQSSEEQMVQLLQLAIDCVAQVPDARPTMSHVVVRIEEI 239 L+ + +QL+QL C + PD RP++ + + + I Sbjct: 781 RPLVSPDQGPLECIQLMQL---CWEEAPDDRPSLDQIYTQFKSI 821
>MK11_MOUSE (Q9WUI1) Mitogen-activated protein kinase 11 (EC 2.7.11.24)| (Mitogen-activated protein kinase p38 beta) (MAP kinase p38 beta) (p38B) Length = 364 Score = 49.3 bits (116), Expect = 1e-05 Identities = 29/85 (34%), Positives = 47/85 (55%), Gaps = 1/85 (1%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATGYRAPEV-TD 539 +YIHS + H ++K SN+ +++ + R+ D GLA +G YRAPE+ + Sbjct: 139 KYIHS--AGIIHRDLKPSNVAVNEDCELRILDFGLAPQADEEMTGYVATRWYRAPEIMLN 196 Query: 538 PRRVSQKADVFSFGVLLLELLTGKA 464 +Q D++S G ++ ELL GKA Sbjct: 197 WMHYNQTVDIWSVGCIMAELLQGKA 221
>IRAK3_MOUSE (Q8K4B2) Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1)| (IRAK-3) (IL-1 receptor-associated kinase M) (IRAK-M) Length = 609 Score = 49.3 bits (116), Expect = 1e-05 Identities = 47/169 (27%), Positives = 76/169 (44%), Gaps = 12/169 (7%) Frame = -1 Query: 715 EYIHSTSS-STSHGNIKSSNILLSKAYQARVSDNGLA----TLVGSSSS-----GPSRAT 566 +Y+H+T + GN+ S+NILL Q +++D A L SS+ G + Sbjct: 292 QYLHNTQPCAVICGNVSSANILLDDQLQPKLTDFAAAHFRPNLEQQSSTINMTGGGRKHL 351 Query: 565 GYRAPEVTDPRRVSQKADVFSFGVLLLELLTGKAPSQSALND-EGVDLPRWVQSVVRSEW 389 Y E R+S K DV+SFG++++E+LTG + L+D + V L + ++ Sbjct: 352 WYMPEEYIRQGRLSVKTDVYSFGIVIMEVLTG---CKVVLDDPKHVQLRDLLMELMEKRG 408 Query: 388 TSEVFD-MELLRNQSSEEQMVQLLQLAIDCVAQVPDARPTMSHVVVRIE 245 ++ +L LA CVA RPTM V+ +E Sbjct: 409 LDSCLSFLDRKIPPCPRNFSAKLFSLAGRCVATKAKLRPTMDEVLSSLE 457
>MK11_HUMAN (Q15759) Mitogen-activated protein kinase 11 (EC 2.7.11.24)| (Mitogen-activated protein kinase p38 beta) (MAP kinase p38 beta) (p38b) (p38-2) (Stress-activated protein kinase 2) Length = 372 Score = 49.3 bits (116), Expect = 1e-05 Identities = 29/85 (34%), Positives = 47/85 (55%), Gaps = 1/85 (1%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATGYRAPEV-TD 539 +YIHS + H ++K SN+ +++ + R+ D GLA +G YRAPE+ + Sbjct: 147 KYIHS--AGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEMTGYVATRWYRAPEIMLN 204 Query: 538 PRRVSQKADVFSFGVLLLELLTGKA 464 +Q D++S G ++ ELL GKA Sbjct: 205 WMHYNQTVDIWSVGCIMAELLQGKA 229
>GUC2D_CANFA (O19179) Retinal guanylyl cyclase 1 precursor (EC 4.6.1.2) (Guanylate| cyclase 2D, retinal) (RETGC-1) (Rod outer segment membrane guanylate cyclase) (ROS-GC) (Guanylate cyclase E) (GC-E) Length = 1109 Score = 49.3 bits (116), Expect = 1e-05 Identities = 50/168 (29%), Positives = 80/168 (47%), Gaps = 10/168 (5%) Frame = -1 Query: 712 YIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSS---SGPSRATG-YRAPEV 545 Y+H +HG +KS N ++ + +V+D+G A L+ + PS + APE+ Sbjct: 660 YLHHRG--VAHGRLKSRNCVVDGRFVLKVTDHGHARLMEAQRVLLEPPSAEDQLWTAPEL 717 Query: 544 T-DP---RRVSQKADVFSFGVLLLELLTGKAPSQSALNDEGVDL-PRWVQSVVRSEWTSE 380 DP RR + DVFS G+++ E++ AP ++L P V VRS Sbjct: 718 LRDPALERRGTLPGDVFSLGIIMQEVVCRSAPYAM------LELTPEEVVERVRSP---- 767 Query: 379 VFDMELLRNQSSEEQM-VQLLQLAIDCVAQVPDARPTMSHVVVRIEEI 239 L R S +Q V+ +QL C A+ PD RP++ H+ + + I Sbjct: 768 ---PPLCRPSVSMDQAPVECIQLMKQCWAEHPDLRPSLGHIFDQFKSI 812
>YES_XIPHE (P27447) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 543 Score = 48.9 bits (115), Expect = 2e-05 Identities = 40/152 (26%), Positives = 72/152 (47%), Gaps = 5/152 (3%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSS----SGPSRATGYRAPEVTDPRRVSQKA 515 H +++++NIL++ +++D GLA L+ + G + APE R + K+ Sbjct: 394 HRDLRAANILVADNLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS 453 Query: 514 DVFSFGVLLLELLT-GKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFDMELLRNQSSEE 338 DV+SFG+LL EL+T G+ P +N E + E + M Q E Sbjct: 454 DVWSFGILLTELVTKGRVPYPGMVNREVL------------EQVDRGYRMPC--PQGCPE 499 Query: 337 QMVQLLQLAIDCVAQVPDARPTMSHVVVRIEE 242 + ++++ C + PD RPT ++ +E+ Sbjct: 500 SLHEMMR---QCWKKEPDERPTFEYIQSFLED 528
>SRC2_XENLA (P13116) Tyrosine-protein kinase Src-2 (EC 2.7.10.2) (p60-Src-2)| Length = 531 Score = 48.9 bits (115), Expect = 2e-05 Identities = 31/90 (34%), Positives = 50/90 (55%), Gaps = 5/90 (5%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSS----SGPSRATGYRAPEVTDPRRVSQKA 515 H +++++NIL+ + +V+D GLA L+ + G + APE R + K+ Sbjct: 382 HRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS 441 Query: 514 DVFSFGVLLLELLT-GKAPSQSALNDEGVD 428 DV+SFG+LL EL T G+ P +N E +D Sbjct: 442 DVWSFGILLTELTTKGRVPYPGMVNREVLD 471
>SRC1_XENLA (P13115) Tyrosine-protein kinase Src-1 (EC 2.7.10.2) (p60-Src-1)| Length = 531 Score = 48.9 bits (115), Expect = 2e-05 Identities = 31/90 (34%), Positives = 50/90 (55%), Gaps = 5/90 (5%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSS----SGPSRATGYRAPEVTDPRRVSQKA 515 H +++++NIL+ + +V+D GLA L+ + G + APE R + K+ Sbjct: 382 HRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS 441 Query: 514 DVFSFGVLLLELLT-GKAPSQSALNDEGVD 428 DV+SFG+LL EL T G+ P +N E +D Sbjct: 442 DVWSFGILLTELTTKGRVPYPGMVNREVLD 471
>CLA4_ASHGO (Q9HFW2) Serine/threonine-protein kinase CLA4 (EC 2.7.11.1)| Length = 793 Score = 48.9 bits (115), Expect = 2e-05 Identities = 28/85 (32%), Positives = 45/85 (52%), Gaps = 3/85 (3%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATG---YRAPEVTDPRRVSQKAD 512 H +IKS N+LL + +++D G + S + G + APEV R +K D Sbjct: 642 HRDIKSDNVLLDTHGRVKITDFGFCAKLTDKRSKRATMVGTPYWMAPEVVKQREYDEKVD 701 Query: 511 VFSFGVLLLELLTGKAPSQSALNDE 437 V+S G++ +E+L G+ P LN+E Sbjct: 702 VWSLGIMTIEMLEGEPP---YLNEE 723
>LRRK1_HUMAN (Q38SD2) Leucine-rich repeat serine/threonine-protein kinase 1 (EC| 2.7.11.1) Length = 2038 Score = 48.9 bits (115), Expect = 2e-05 Identities = 39/151 (25%), Positives = 71/151 (47%), Gaps = 6/151 (3%) Frame = -1 Query: 676 NIKSSNILL-----SKAYQARVSDNGLATL-VGSSSSGPSRATGYRAPEVTDPRRVSQKA 515 ++KS NIL+ + ++SD G++ + G GY+APE+ +K Sbjct: 1409 DLKSDNILVWSLDVKEHINIKLSDYGISRQSFHEGALGVEGTPGYQAPEIRPRIVYDEKV 1468 Query: 514 DVFSFGVLLLELLTGKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFDMELLRNQSSEEQ 335 D+FS+G++L ELL+G+ P AL + + + + +R + Q E Q Sbjct: 1469 DMFSYGMVLYELLSGQRP---ALGHHQLQIAKKLSKGIRP-----------VLGQPEEVQ 1514 Query: 334 MVQLLQLAIDCVAQVPDARPTMSHVVVRIEE 242 +L L ++C P+ RP VV ++++ Sbjct: 1515 FRRLQALMMECWDTKPEKRPLALSVVSQMKD 1545
>SRC_RSVPA (P31693) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 522 Score = 48.9 bits (115), Expect = 2e-05 Identities = 31/90 (34%), Positives = 50/90 (55%), Gaps = 5/90 (5%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSS----SGPSRATGYRAPEVTDPRRVSQKA 515 H +++++NIL+ + +V+D GLA L+ + G + APE R + K+ Sbjct: 380 HRDLRAANILVGENLVCKVADFGLARLIEDNEYTARPGARFPVKWTAPEAALYGRFTIKS 439 Query: 514 DVFSFGVLLLELLT-GKAPSQSALNDEGVD 428 DV+SFG+LL EL T G+ P +N E +D Sbjct: 440 DVWSFGILLTELTTKGRVPYPGMVNGEVLD 469
>CLA4_YEAST (P48562) Serine/threonine-protein kinase CLA4 (EC 2.7.11.1)| Length = 842 Score = 48.9 bits (115), Expect = 2e-05 Identities = 25/77 (32%), Positives = 41/77 (53%), Gaps = 3/77 (3%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATG---YRAPEVTDPRRVSQKAD 512 H +IKS N+LL + +++D G + S + G + APEV R +K D Sbjct: 691 HRDIKSDNVLLDTRARVKITDFGFCARLTDKRSKRATMVGTPYWMAPEVVKQREYDEKID 750 Query: 511 VFSFGVLLLELLTGKAP 461 V+S G++ +E+L G+ P Sbjct: 751 VWSLGIMTIEMLEGEPP 767
>SRC_RSVP (P00526) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 48.9 bits (115), Expect = 2e-05 Identities = 31/90 (34%), Positives = 50/90 (55%), Gaps = 5/90 (5%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSS----SGPSRATGYRAPEVTDPRRVSQKA 515 H +++++NIL+ + +V+D GLA L+ + G + APE R + K+ Sbjct: 383 HRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS 442 Query: 514 DVFSFGVLLLELLT-GKAPSQSALNDEGVD 428 DV+SFG+LL EL T G+ P +N E +D Sbjct: 443 DVWSFGILLTELTTKGRVPYPGMVNREVLD 472
>SRC_RSVH1 (P25020) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 48.9 bits (115), Expect = 2e-05 Identities = 31/90 (34%), Positives = 50/90 (55%), Gaps = 5/90 (5%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSS----SGPSRATGYRAPEVTDPRRVSQKA 515 H +++++NIL+ + +V+D GLA L+ + G + APE R + K+ Sbjct: 383 HRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS 442 Query: 514 DVFSFGVLLLELLT-GKAPSQSALNDEGVD 428 DV+SFG+LL EL T G+ P +N E +D Sbjct: 443 DVWSFGILLTELTTKGRVPYPGMVNREVLD 472
>KAPC_YEAST (P05986) cAMP-dependent protein kinase type 3 (EC 2.7.11.11) (PKA| 3) Length = 398 Score = 48.9 bits (115), Expect = 2e-05 Identities = 29/85 (34%), Positives = 43/85 (50%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATGYRAPEVTDP 536 EY+HS + ++K NILL K +++D G A V + Y APEV Sbjct: 200 EYLHS--KDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTYTLCGTPDYIAPEVVST 257 Query: 535 RRVSQKADVFSFGVLLLELLTGKAP 461 + ++ D +SFGVL+ E+L G P Sbjct: 258 KPYNKSVDWWSFGVLIYEMLAGYTP 282
>TOPK_MOUSE (Q9JJ78) T-lymphokine-activated killer cell-originated protein| kinase (EC 2.7.12.2) (T-LAK cell-originated protein kinase) (PDZ-binding kinase) Length = 330 Score = 48.9 bits (115), Expect = 2e-05 Identities = 44/170 (25%), Positives = 81/170 (47%), Gaps = 13/170 (7%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQA-RVSDNGLATLVGSSSSGPSRATGYRAPEVTD 539 +Y+H HG+IKSSN+++ ++ ++ D G++ + + + Y E Sbjct: 154 KYLHQ-EKKLLHGDIKSSNVVIKGDFETIKICDVGVSLPLDENMTVTDPEACYIGTEPWK 212 Query: 538 PRR-------VSQKADVFSFGVLLLELLTGKAPSQSALNDEGVDLPRWVQSVVRSEWTSE 380 P+ ++ KADVF+FG+ L E++T P + L D+ VD + S++ E Sbjct: 213 PKEALEENGIITDKADVFAFGLTLWEMMTLCIPHVN-LPDDDVDED---ATFDESDFDDE 268 Query: 379 VFDMEL-LRNQSSEEQMVQLLQLAID----CVAQVPDARPTMSHVVVRIE 245 + L R + E++ Q AI+ C + P RP+ +H+V +E Sbjct: 269 AYYAALGTRPSINMEELDDSYQKAIELFCVCTNEDPKDRPSAAHIVEALE 318
>STE20_YEAST (Q03497) Serine/threonine-protein kinase STE20 (EC 2.7.11.1)| Length = 939 Score = 48.9 bits (115), Expect = 2e-05 Identities = 26/88 (29%), Positives = 46/88 (52%), Gaps = 3/88 (3%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATG---YRAPEV 545 E++HS H +IKS NILLS +++D G + + + G + APEV Sbjct: 728 EFLHS--KGVLHRDIKSDNILLSMEGDIKLTDFGFCAQINELNLKRTTMVGTPYWMAPEV 785 Query: 544 TDPRRVSQKADVFSFGVLLLELLTGKAP 461 + K D++S G++++E++ G+ P Sbjct: 786 VSRKEYGPKVDIWSLGIMIIEMIEGEPP 813
>PKNA2_BIFLO (Q8G4G1) Probable serine/threonine-protein kinase pknA2 (EC| 2.7.11.1) Length = 757 Score = 48.9 bits (115), Expect = 2e-05 Identities = 28/81 (34%), Positives = 45/81 (55%), Gaps = 4/81 (4%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGS---SSSGPSRATG-YRAPEVTDPRRVSQKA 515 H +IK NIL++ +++D GLA SS+G T Y APE+ + + + + Sbjct: 138 HRDIKPENILINDRGHVQITDFGLAKAASQATLSSTGMLLGTAAYLAPEMIENNQATAQG 197 Query: 514 DVFSFGVLLLELLTGKAPSQS 452 D++S G++ E+LTGK P S Sbjct: 198 DLYSVGIMAWEMLTGKVPFDS 218
>ITK_HUMAN (Q08881) Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2)| (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT) Length = 620 Score = 48.9 bits (115), Expect = 2e-05 Identities = 44/153 (28%), Positives = 72/153 (47%), Gaps = 5/153 (3%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLV----GSSSSGPSRATGYRAPEVTDPRRVSQKA 515 H ++ + N L+ + +VSD G+ V +SS+G + +PEV R S K+ Sbjct: 480 HRDLAARNCLVGENQVIKVSDFGMTRFVLDDQYTSSTGTKFPVKWASPEVFSFSRYSSKS 539 Query: 514 DVFSFGVLLLELLT-GKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFDMELLRNQSSEE 338 DV+SFGVL+ E+ + GK P ++ N E V E S F + R S+ Sbjct: 540 DVWSFGVLMWEVFSEGKIPYENRSNSEVV------------EDISTGFRLYKPRLAST-- 585 Query: 337 QMVQLLQLAIDCVAQVPDARPTMSHVVVRIEEI 239 + Q+ C + P+ RP S ++ ++ EI Sbjct: 586 ---HVYQIMNHCWKERPEDRPAFSRLLRQLAEI 615
>PKNJ_MYCTU (P65732) Probable serine/threonine-protein kinase pknJ (EC| 2.7.11.1) Length = 589 Score = 48.5 bits (114), Expect = 2e-05 Identities = 35/93 (37%), Positives = 50/93 (53%), Gaps = 8/93 (8%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAY----QARVSDNGLATLVGSS---SSGPSRAT-GY 560 +Y H H +IK +N LLS+A + +SD G+A +G + S+G AT Y Sbjct: 125 DYAHQ--QGVIHRDIKPANFLLSRAAGGDERVLLSDFGIARALGDTGLTSTGSVLATLAY 182 Query: 559 RAPEVTDPRRVSQKADVFSFGVLLLELLTGKAP 461 APEV + +AD++S G L LLTG+AP Sbjct: 183 AAPEVLAGQGFDGRADLYSLGCALFRLLTGEAP 215
>PKNJ_MYCBO (P65733) Probable serine/threonine-protein kinase pknJ (EC| 2.7.11.1) Length = 589 Score = 48.5 bits (114), Expect = 2e-05 Identities = 35/93 (37%), Positives = 50/93 (53%), Gaps = 8/93 (8%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAY----QARVSDNGLATLVGSS---SSGPSRAT-GY 560 +Y H H +IK +N LLS+A + +SD G+A +G + S+G AT Y Sbjct: 125 DYAHQ--QGVIHRDIKPANFLLSRAAGGDERVLLSDFGIARALGDTGLTSTGSVLATLAY 182 Query: 559 RAPEVTDPRRVSQKADVFSFGVLLLELLTGKAP 461 APEV + +AD++S G L LLTG+AP Sbjct: 183 AAPEVLAGQGFDGRADLYSLGCALFRLLTGEAP 215
>GRK1_CAEEL (Q09537) G protein-coupled receptor kinase 1 (EC 2.7.11.16)| Length = 642 Score = 48.5 bits (114), Expect = 2e-05 Identities = 29/84 (34%), Positives = 40/84 (47%), Gaps = 2/84 (2%) Frame = -1 Query: 706 HSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSS--SGPSRATGYRAPEVTDPR 533 H S + ++K NILL R+SD GLA + + G GY APE+ Sbjct: 318 HLHSERILYRDLKPENILLDDFGHVRISDLGLAVEIKDNEPIKGRVGTVGYMAPEIVKNE 377 Query: 532 RVSQKADVFSFGVLLLELLTGKAP 461 R S D + G L+ E++ GKAP Sbjct: 378 RYSYGVDWWGVGCLIYEMIEGKAP 401
>PAK1_RAT (P35465) Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1)| (p21-activated kinase 1) (PAK-1) (P68-PAK) (Alpha-PAK) (Protein kinase MUK2) Length = 544 Score = 48.5 bits (114), Expect = 2e-05 Identities = 27/88 (30%), Positives = 45/88 (51%), Gaps = 3/88 (3%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATG---YRAPEV 545 E++HS + H +IKS NILL +++D G + S S G + APEV Sbjct: 377 EFLHS--NQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEV 434 Query: 544 TDPRRVSQKADVFSFGVLLLELLTGKAP 461 + K D++S G++ +E++ G+ P Sbjct: 435 VTRKAYGPKVDIWSLGIMAIEMIEGEPP 462
>STE20_CANAL (Q92212) Serine/threonine-protein kinase STE20 homolog (EC 2.7.11.1)| Length = 1230 Score = 48.5 bits (114), Expect = 2e-05 Identities = 26/88 (29%), Positives = 46/88 (52%), Gaps = 3/88 (3%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATG---YRAPEV 545 +++HS H +IKS NILL+ +++D G + +S G + APE+ Sbjct: 1062 KFLHS--KGVIHRDIKSDNILLNMDGNIKITDFGFCAQINEINSKRITMVGTPYWMAPEI 1119 Query: 544 TDPRRVSQKADVFSFGVLLLELLTGKAP 461 + K DV+S G++++E+L G+ P Sbjct: 1120 VSRKEYGPKVDVWSLGIMIIEMLEGEPP 1147
>ITK_MOUSE (Q03526) Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2)| (T-cell-specific kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK) Length = 625 Score = 48.5 bits (114), Expect = 2e-05 Identities = 44/153 (28%), Positives = 71/153 (46%), Gaps = 5/153 (3%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLV----GSSSSGPSRATGYRAPEVTDPRRVSQKA 515 H ++ + N L+ + +VSD G+ V +SS+G + +PEV R S K+ Sbjct: 485 HRDLAARNCLVGENQVIKVSDFGMTRFVLDDQYTSSTGTKFPVKWASPEVFSFSRYSSKS 544 Query: 514 DVFSFGVLLLELLT-GKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFDMELLRNQSSEE 338 DV+SFGVL+ E+ + GK P ++ N E V E S F + R S Sbjct: 545 DVWSFGVLMWEVFSEGKIPYENRSNSEVV------------EDISTGFRLYKPRLAS--- 589 Query: 337 QMVQLLQLAIDCVAQVPDARPTMSHVVVRIEEI 239 + Q+ C + P+ RP S ++ ++ EI Sbjct: 590 --CHVYQIMNHCWKEKPEDRPPFSQLLSQLAEI 620
>HCK_MACFA (Q95M30) Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK)| (Hemopoietic cell kinase) Length = 503 Score = 48.5 bits (114), Expect = 2e-05 Identities = 36/146 (24%), Positives = 70/146 (47%), Gaps = 5/146 (3%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSS----SGPSRATGYRAPEVTDPRRVSQKA 515 H +++++NIL+S + +++D GLA ++ + G + APE + + K+ Sbjct: 356 HRDLRAANILVSASLVCKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAINFGSSTIKS 415 Query: 514 DVFSFGVLLLELLT-GKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFDMELLRNQSSEE 338 DV+SFG+LL+E++T G+ P G+ P ++++ R R E Sbjct: 416 DVWSFGILLMEIVTYGRIPY------PGMSNPEVIRALERG-----------YRMPRPEN 458 Query: 337 QMVQLLQLAIDCVAQVPDARPTMSHV 260 +L + + C P+ RPT ++ Sbjct: 459 CPEELYNIMMRCWKNRPEERPTFEYI 484
>KS6A2_HUMAN (Q15349) Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1)| (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (MAP kinase-activated protein kinase 1c) (MAPKAPK1C) Length = 733 Score = 48.5 bits (114), Expect = 2e-05 Identities = 31/87 (35%), Positives = 44/87 (50%), Gaps = 3/87 (3%) Frame = -1 Query: 706 HSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATG---YRAPEVTDP 536 H S + ++K NILL + +++D GL+ G Y APEV + Sbjct: 174 HLHSLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNR 233 Query: 535 RRVSQKADVFSFGVLLLELLTGKAPSQ 455 R +Q AD +SFGVL+ E+LTG P Q Sbjct: 234 RGHTQSADWWSFGVLMFEMLTGSLPFQ 260 Score = 37.4 bits (85), Expect = 0.046 Identities = 28/99 (28%), Positives = 43/99 (43%), Gaps = 7/99 (7%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILL----SKAYQARVSDNGLATLVGSSSS---GPSRATGYR 557 +Y+HS H ++K SNIL RV D G A + + + P + Sbjct: 521 DYLHS--QGVVHRDLKPSNILYRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANFV 578 Query: 556 APEVTDPRRVSQKADVFSFGVLLLELLTGKAPSQSALND 440 APEV + D++S G+LL +L G P + +D Sbjct: 579 APEVLKRQGYDAACDIWSLGILLYTMLAGFTPFANGPDD 617
>PAK1_MOUSE (O88643) Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1)| (p21-activated kinase 1) (PAK-1) (P65-PAK) (Alpha-PAK) (CDC42/RAC effector kinase PAK-A) Length = 545 Score = 48.5 bits (114), Expect = 2e-05 Identities = 27/88 (30%), Positives = 45/88 (51%), Gaps = 3/88 (3%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATG---YRAPEV 545 E++HS + H +IKS NILL +++D G + S S G + APEV Sbjct: 378 EFLHS--NQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEV 435 Query: 544 TDPRRVSQKADVFSFGVLLLELLTGKAP 461 + K D++S G++ +E++ G+ P Sbjct: 436 VTRKAYGPKVDIWSLGIMAIEMIEGEPP 463
>PAK1_HUMAN (Q13153) Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1)| (p21-activated kinase 1) (PAK-1) (P65-PAK) (Alpha-PAK) Length = 545 Score = 48.5 bits (114), Expect = 2e-05 Identities = 27/88 (30%), Positives = 45/88 (51%), Gaps = 3/88 (3%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATG---YRAPEV 545 E++HS + H +IKS NILL +++D G + S S G + APEV Sbjct: 378 EFLHS--NQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEV 435 Query: 544 TDPRRVSQKADVFSFGVLLLELLTGKAP 461 + K D++S G++ +E++ G+ P Sbjct: 436 VTRKAYGPKVDIWSLGIMAIEMIEGEPP 463
>HCK_HUMAN (P08631) Tyrosine-protein kinase HCK (EC 2.7.10.2)| (p59-HCK/p60-HCK) (Hemopoietic cell kinase) Length = 525 Score = 48.5 bits (114), Expect = 2e-05 Identities = 36/146 (24%), Positives = 70/146 (47%), Gaps = 5/146 (3%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSS----SGPSRATGYRAPEVTDPRRVSQKA 515 H +++++NIL+S + +++D GLA ++ + G + APE + + K+ Sbjct: 378 HRDLRAANILVSASLVCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGSFTIKS 437 Query: 514 DVFSFGVLLLELLT-GKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFDMELLRNQSSEE 338 DV+SFG+LL+E++T G+ P G+ P ++++ R R E Sbjct: 438 DVWSFGILLMEIVTYGRIPY------PGMSNPEVIRALERG-----------YRMPRPEN 480 Query: 337 QMVQLLQLAIDCVAQVPDARPTMSHV 260 +L + + C P+ RPT ++ Sbjct: 481 CPEELYNIMMRCWKNRPEERPTFEYI 506
>YES_HUMAN (P07947) Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2)| (p61-Yes) (c-Yes) Length = 542 Score = 48.5 bits (114), Expect = 2e-05 Identities = 41/152 (26%), Positives = 72/152 (47%), Gaps = 5/152 (3%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSS----SGPSRATGYRAPEVTDPRRVSQKA 515 H +++++NIL+ + +++D GLA L+ + G + APE R + K+ Sbjct: 393 HRDLRAANILVGENLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS 452 Query: 514 DVFSFGVLLLELLT-GKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFDMELLRNQSSEE 338 DV+SFG+L EL+T G+ P +N E ++ V R + Q E Sbjct: 453 DVWSFGILQTELVTKGRVPYPGMVNRE------VLEQVERG--------YRMPCPQGCPE 498 Query: 337 QMVQLLQLAIDCVAQVPDARPTMSHVVVRIEE 242 + +L+ L C + PD RPT ++ +E+ Sbjct: 499 SLHELMNL---CWKKDPDERPTFEYIQSFLED 527
>TXK_MOUSE (P42682) Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18)| (Resting lymphocyte kinase) Length = 527 Score = 48.5 bits (114), Expect = 2e-05 Identities = 33/90 (36%), Positives = 50/90 (55%), Gaps = 5/90 (5%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGS----SSSGPSRATGYRAPEVTDPRRVSQKA 515 H ++ + N L+S A ++SD G+A V SSSG + PEV + S K+ Sbjct: 388 HRDLAARNCLVSSACVVKISDFGMARYVLDDEYISSSGAKFPVKWCPPEVFHFNKYSSKS 447 Query: 514 DVFSFGVLLLELLT-GKAPSQSALNDEGVD 428 DV+SFGVL+ E+ T GK P ++ N + V+ Sbjct: 448 DVWSFGVLMWEVFTEGKMPFENKSNLQVVE 477
>CHK1_SCHPO (P34208) Serine/threonine-protein kinase chk1 (EC 2.7.11.1)| (Checkpoint kinase 1) Length = 496 Score = 48.5 bits (114), Expect = 2e-05 Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 5/93 (5%) Frame = -1 Query: 697 SSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSS-----SGPSRATGYRAPEVTDPR 533 S +H ++K NILL ++SD G A+L + P + Y APE+T + Sbjct: 130 SKGVAHRDLKPENILLDYNGNLKISDFGFASLFSYKGKSRLLNSPVGSPPYAAPEITQ-Q 188 Query: 532 RVSQKADVFSFGVLLLELLTGKAPSQSALNDEG 434 K DV+S G++L LL G P A+++ G Sbjct: 189 YDGSKVDVWSCGIILFALLLGNTPWDEAISNTG 221
>LRRK1_MOUSE (Q3UHC2) Leucine-rich repeat serine/threonine-protein kinase 1 (EC| 2.7.11.1) Length = 2014 Score = 48.5 bits (114), Expect = 2e-05 Identities = 39/151 (25%), Positives = 71/151 (47%), Gaps = 6/151 (3%) Frame = -1 Query: 676 NIKSSNILL-----SKAYQARVSDNGLATL-VGSSSSGPSRATGYRAPEVTDPRRVSQKA 515 ++KS NIL+ + ++SD G++ + G GY+APE+ +K Sbjct: 1386 DLKSDNILVWSLSAKEHINIKLSDYGISRQSFHEGALGVEGTPGYQAPEIRPRIVYDEKV 1445 Query: 514 DVFSFGVLLLELLTGKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFDMELLRNQSSEEQ 335 D+FS+G++L ELL+G+ P AL + + + + +R + Q E Q Sbjct: 1446 DMFSYGMVLYELLSGQRP---ALGHHQLQIVKKLSKGIRP-----------VLGQPEEVQ 1491 Query: 334 MVQLLQLAIDCVAQVPDARPTMSHVVVRIEE 242 +L L ++C P+ RP VV ++++ Sbjct: 1492 FHRLQALMMECWDTKPEKRPLALSVVSQMKD 1522
>GRK6_HUMAN (P43250) G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK6) Length = 576 Score = 48.5 bits (114), Expect = 2e-05 Identities = 29/76 (38%), Positives = 40/76 (52%), Gaps = 2/76 (2%) Frame = -1 Query: 676 NIKSSNILLSKAYQARVSDNGLATLV--GSSSSGPSRATGYRAPEVTDPRRVSQKADVFS 503 ++K NILL R+SD GLA V G + G GY APEV R + D ++ Sbjct: 311 DLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVKNERYTFSPDWWA 370 Query: 502 FGVLLLELLTGKAPSQ 455 G LL E++ G++P Q Sbjct: 371 LGCLLYEMIAGQSPFQ 386
>CDS1_SCHPO (Q09170) Serine/threonine-protein kinase cds1 (EC 2.7.11.1)| (Checkpoint kinase cds1) Length = 460 Score = 48.5 bits (114), Expect = 2e-05 Identities = 37/133 (27%), Positives = 62/133 (46%), Gaps = 9/133 (6%) Frame = -1 Query: 709 IHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLV---GSSSSGPSRATGYRAPEVTD 539 +H +H +IK NIL++ + ++SD GLA ++ G+ GY APEV Sbjct: 283 LHLHKQGVTHRDIKPENILITNDFHLKISDFGLAKVIHGTGTFLETFCGTMGYLAPEVLK 342 Query: 538 PRRVS------QKADVFSFGVLLLELLTGKAPSQSALNDEGVDLPRWVQSVVRSEWTSEV 377 + V+ K D++S G +L +LT P S+ + ++L + + + E Sbjct: 343 SKNVNLDGGYDDKVDIWSLGCVLYVMLTASIPFASSSQAKCIEL------ISKGAYPIE- 395 Query: 376 FDMELLRNQSSEE 338 LL N+ SEE Sbjct: 396 ---PLLENEISEE 405
>YES_MOUSE (Q04736) Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2)| (p61-Yes) (c-Yes) Length = 540 Score = 48.1 bits (113), Expect = 3e-05 Identities = 41/152 (26%), Positives = 72/152 (47%), Gaps = 5/152 (3%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSS----SGPSRATGYRAPEVTDPRRVSQKA 515 H +++++NIL+ + +++D GLA L+ + G + APE R + K+ Sbjct: 391 HRDLRAANILVGENLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS 450 Query: 514 DVFSFGVLLLELLT-GKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFDMELLRNQSSEE 338 DV+SFG+L EL+T G+ P +N E ++ V R + Q E Sbjct: 451 DVWSFGILQTELVTKGRVPYPGMVNRE------VLEQVERG--------YRMPCPQGCPE 496 Query: 337 QMVQLLQLAIDCVAQVPDARPTMSHVVVRIEE 242 + +L+ L C + PD RPT ++ +E+ Sbjct: 497 SLHELMNL---CWKKDPDERPTFEYIQSFLED 525
>FGR_HUMAN (P09769) Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2)| (P55-FGR) (C-FGR) Length = 529 Score = 48.1 bits (113), Expect = 3e-05 Identities = 27/79 (34%), Positives = 47/79 (59%), Gaps = 5/79 (6%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATGY----RAPEVTDPRRVSQKA 515 H +++++NIL+ + +++D GLA L+ P + + + APE R + K+ Sbjct: 380 HRDLRAANILVGERLACKIADFGLARLIKDDEYNPCQGSKFPIKWTAPEAALFGRFTIKS 439 Query: 514 DVFSFGVLLLELLT-GKAP 461 DV+SFG+LL EL+T G+ P Sbjct: 440 DVWSFGILLTELITKGRIP 458
>SPKA_SYNY3 (Q9FAB3) Serine/threonine-protein kinase A (EC 2.7.11.1)| Length = 521 Score = 48.1 bits (113), Expect = 3e-05 Identities = 38/152 (25%), Positives = 71/152 (46%), Gaps = 8/152 (5%) Frame = -1 Query: 682 HGNIKSSNILLSK----AYQARVSDNGLATLVGSSSSGPSRA----TGYRAPEVTDPRRV 527 H +IK SN+LL + ++ D G+A LV ++ ++A Y +PE + + + Sbjct: 146 HRDIKPSNVLLVEDPALGELVKILDFGIAKLVQAAEESKTQAFMGTLAYCSPEQMEGKEL 205 Query: 526 SQKADVFSFGVLLLELLTGKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFDMELLRNQS 347 ++D++S GV++ E+LTG+ P L + W ++ ++ F S Sbjct: 206 DSRSDIYSLGVMMYEMLTGEMP----LFPDNSSFGGWYEAHHHTK--PHPFSARYKIPAS 259 Query: 346 SEEQMVQLLQLAIDCVAQVPDARPTMSHVVVR 251 E L ++C+A+ P RP V++R Sbjct: 260 LEA-------LVMNCLAKSPKGRPQSVDVIIR 284
>HCK_MOUSE (P08103) Tyrosine-protein kinase HCK (EC 2.7.10.2)| (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK) Length = 523 Score = 48.1 bits (113), Expect = 3e-05 Identities = 36/146 (24%), Positives = 67/146 (45%), Gaps = 5/146 (3%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSS----SGPSRATGYRAPEVTDPRRVSQKA 515 H +++++NIL+S + +++D GLA ++ + G + APE + + K+ Sbjct: 376 HRDLRAANILVSASLVCKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAINFGSFTIKS 435 Query: 514 DVFSFGVLLLELLT-GKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFDMELLRNQSSEE 338 DV+SFG+LL+E++T G+ P N E + + R + E Sbjct: 436 DVWSFGILLMEIVTYGRIPYPGMSNPEVIRALEHGYRMPRPDNCPE-------------- 481 Query: 337 QMVQLLQLAIDCVAQVPDARPTMSHV 260 +L + I C P+ RPT ++ Sbjct: 482 ---ELYNIMIRCWKNRPEERPTFEYI 504
>SKM1_YEAST (Q12469) Serine/threonine-protein kinase SKM1 (EC 2.7.11.1)| (Protein kinase 75490 D) Length = 655 Score = 48.1 bits (113), Expect = 3e-05 Identities = 24/77 (31%), Positives = 43/77 (55%), Gaps = 3/77 (3%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATG---YRAPEVTDPRRVSQKAD 512 H +IKS NILL+ +++D G + S + G + APE+ + + +K D Sbjct: 505 HRDIKSDNILLNSQGLVKITDFGFCVELTEKRSKRATMVGTPYWMAPEIVNQKGYDEKVD 564 Query: 511 VFSFGVLLLELLTGKAP 461 V+S G++L+E++ G+ P Sbjct: 565 VWSLGIMLIEMIEGEPP 581
>YES_XENLA (P10936) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 536 Score = 48.1 bits (113), Expect = 3e-05 Identities = 41/152 (26%), Positives = 72/152 (47%), Gaps = 5/152 (3%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSS----SGPSRATGYRAPEVTDPRRVSQKA 515 H +++++NIL+ +++D GLA L+ + G + APE R + K+ Sbjct: 387 HRDLRAANILVGDNLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS 446 Query: 514 DVFSFGVLLLELLT-GKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFDMELLRNQSSEE 338 DV+SFG+LL EL+ G+ P +N E ++ V R + Q E Sbjct: 447 DVWSFGILLTELVAKGRVPYPGMVNRE------VLEQVERG--------YRMPCPQRCPE 492 Query: 337 QMVQLLQLAIDCVAQVPDARPTMSHVVVRIEE 242 + +L++L C + PD RPT ++ +E+ Sbjct: 493 SLHELMKL---CWKKDPDERPTFEYIQSFLED 521
>KAPA_YEAST (P06244) cAMP-dependent protein kinase type 1 (EC 2.7.11.11) (PKA| 1) (CDC25-suppressing protein kinase) (PK-25) Length = 397 Score = 48.1 bits (113), Expect = 3e-05 Identities = 28/85 (32%), Positives = 43/85 (50%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATGYRAPEVTDP 536 EY+HS + ++K NILL K +++D G A V + Y APEV Sbjct: 199 EYLHS--KDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTYTLCGTPDYIAPEVVST 256 Query: 535 RRVSQKADVFSFGVLLLELLTGKAP 461 + ++ D +SFG+L+ E+L G P Sbjct: 257 KPYNKSIDWWSFGILIYEMLAGYTP 281
>KS6A2_MOUSE (Q9WUT3) Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1)| (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (Protein-tyrosine kinase Mpk-9) (MAP kinase-activated protein kinase 1c) (M Length = 733 Score = 48.1 bits (113), Expect = 3e-05 Identities = 29/77 (37%), Positives = 41/77 (53%), Gaps = 3/77 (3%) Frame = -1 Query: 676 NIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATG---YRAPEVTDPRRVSQKADVF 506 ++K NILL + +++D GL+ G Y APEV + R +Q AD + Sbjct: 184 DLKPENILLDEEGHIKITDFGLSKEATDHDKRAYSFCGTIEYMAPEVVNRRGHTQSADWW 243 Query: 505 SFGVLLLELLTGKAPSQ 455 SFGVL+ E+LTG P Q Sbjct: 244 SFGVLMFEMLTGSLPFQ 260 Score = 37.4 bits (85), Expect = 0.046 Identities = 28/99 (28%), Positives = 43/99 (43%), Gaps = 7/99 (7%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILL----SKAYQARVSDNGLATLVGSSSS---GPSRATGYR 557 +Y+HS H ++K SNIL R+ D G A + + + P + Sbjct: 521 DYLHS--QGVVHRDLKPSNILYMDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFV 578 Query: 556 APEVTDPRRVSQKADVFSFGVLLLELLTGKAPSQSALND 440 APEV + DV+S G+LL +L G P + +D Sbjct: 579 APEVLKRQGYDAACDVWSLGILLYTMLAGFTPFANGPDD 617
>MATK_RAT (P41243) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase BATK) Length = 467 Score = 48.1 bits (113), Expect = 3e-05 Identities = 35/87 (40%), Positives = 48/87 (55%), Gaps = 2/87 (2%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRA-TGYRAPEVTD 539 EY+ S H ++ + NIL+S+ A+VSD GLA SR + APE Sbjct: 300 EYLES--KKLVHRDLAARNILVSEDLVAKVSDFGLAKAELRKGLDSSRLPVKWTAPEALK 357 Query: 538 PRRVSQKADVFSFGVLLLELLT-GKAP 461 R S K+DV+SFGVLL E+ + G+AP Sbjct: 358 NGRFSSKSDVWSFGVLLWEVFSYGRAP 384
>M3K10_HUMAN (Q02779) Mitogen-activated protein kinase kinase kinase 10 (EC| 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST) Length = 954 Score = 48.1 bits (113), Expect = 3e-05 Identities = 46/169 (27%), Positives = 78/169 (46%), Gaps = 10/169 (5%) Frame = -1 Query: 712 YIHSTSS-STSHGNIKSSNILLSKAYQ--------ARVSDNGLATLVGSSSSGPSRAT-G 563 Y+H+ + H ++KS NIL+ +A + +++D GLA ++ + T Sbjct: 209 YLHNDAPVPIIHRDLKSINILILEAIENHNLADTVLKITDFGLAREWHKTTKMSAAGTYA 268 Query: 562 YRAPEVTDPRRVSQKADVFSFGVLLLELLTGKAPSQSALNDEGVDLPRWVQSVVRSEWTS 383 + APEV S+ +DV+SFGVLL ELLTG+ P + +D V ++ T Sbjct: 269 WMAPEVIRLSLFSKSSDVWSFGVLLWELLTGEVPYRE------IDALAVAYGVAMNKLTL 322 Query: 382 EVFDMELLRNQSSEEQMVQLLQLAIDCVAQVPDARPTMSHVVVRIEEIK 236 + + E +LL+ +C P RP ++ R+E I+ Sbjct: 323 PI-------PSTCPEPFARLLE---ECWDPDPHGRPDFGSILKRLEVIE 361
>GRK6_MOUSE (O70293) G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK6) Length = 576 Score = 48.1 bits (113), Expect = 3e-05 Identities = 29/76 (38%), Positives = 40/76 (52%), Gaps = 2/76 (2%) Frame = -1 Query: 676 NIKSSNILLSKAYQARVSDNGLATLV--GSSSSGPSRATGYRAPEVTDPRRVSQKADVFS 503 ++K NILL R+SD GLA V G + G GY APEV R + D ++ Sbjct: 311 DLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVRNERYTFSPDWWA 370 Query: 502 FGVLLLELLTGKAPSQ 455 G LL E++ G++P Q Sbjct: 371 LGCLLYEMIAGQSPFQ 386
>BYR2_SCHPO (P28829) Protein kinase byr2 (EC 2.7.11.25) (Protein kinase ste8)| (MAPK kinase kinase) (MAPKKK) Length = 659 Score = 48.1 bits (113), Expect = 3e-05 Identities = 29/94 (30%), Positives = 48/94 (51%), Gaps = 9/94 (9%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSD---------NGLATLVGSSSSGPSRATG 563 EY+HS H +IK +NIL+ + ++SD N +T G + ++ Sbjct: 511 EYLHSRG--IVHRDIKGANILVDNKGKIKISDFGISKKLELNSTSTKTGGARPSFQGSSF 568 Query: 562 YRAPEVTDPRRVSQKADVFSFGVLLLELLTGKAP 461 + APEV ++K D++S G L++E+LT K P Sbjct: 569 WMAPEVVKQTMHTEKTDIWSLGCLVIEMLTSKHP 602
>HCK_RAT (P50545) Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK)| (Hemopoietic cell kinase) Length = 502 Score = 48.1 bits (113), Expect = 3e-05 Identities = 36/146 (24%), Positives = 67/146 (45%), Gaps = 5/146 (3%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSS----SGPSRATGYRAPEVTDPRRVSQKA 515 H +++++NIL+S + +++D GLA ++ + G + APE + + K+ Sbjct: 355 HRDLRAANILVSASLVCKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAINFGSFTIKS 414 Query: 514 DVFSFGVLLLELLT-GKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFDMELLRNQSSEE 338 DV+SFG+LL+E++T G+ P N E + + R + E Sbjct: 415 DVWSFGILLMEIVTYGRIPYPGMSNPEVIRALEHGYRMPRPDNCPE-------------- 460 Query: 337 QMVQLLQLAIDCVAQVPDARPTMSHV 260 +L + I C P+ RPT ++ Sbjct: 461 ---ELYSIMIRCWKNRPEERPTFEYI 483
>NEK9_MOUSE (Q8K1R7) Serine/threonine-protein kinase Nek9 (EC 2.7.11.1)| (NimA-related protein kinase 9) (Never in mitosis A-related kinase 9) Length = 984 Score = 48.1 bits (113), Expect = 3e-05 Identities = 41/139 (29%), Positives = 67/139 (48%), Gaps = 3/139 (2%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATG---YRAPEVTDPRRVSQKAD 512 H +IK+ NI L+KA ++ D GLA + S S G Y +PE+ + + K+D Sbjct: 174 HRDIKTLNIFLTKANLIKLGDYGLAKKLNSEYSMAETLVGTPYYMSPELCQGVKYNFKSD 233 Query: 511 VFSFGVLLLELLTGKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFDMELLRNQSSEEQM 332 +++ G ++ ELLT K + A N + + + VQ + E S + +E Sbjct: 234 IWAVGCVIFELLTLKR-TFDATNPLNLCV-KIVQGIRAMEVDSSQYSLE----------- 280 Query: 331 VQLLQLAIDCVAQVPDARP 275 L+QL C+ Q P+ RP Sbjct: 281 --LIQLVHACLDQDPEQRP 297
>M3K7_DROME (Q9V3Q6) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (TGF-beta-activated kinase 1) (dTAK1) Length = 678 Score = 47.8 bits (112), Expect = 3e-05 Identities = 40/160 (25%), Positives = 78/160 (48%), Gaps = 2/160 (1%) Frame = -1 Query: 712 YIHS-TSSSTSHGNIKSSNILLS-KAYQARVSDNGLATLVGSSSSGPSRATGYRAPEVTD 539 Y+H+ T H ++K N+LL+ K ++ D G + + + + APEV + Sbjct: 127 YLHAMTPKPLIHRDVKPLNLLLTNKGRNLKICDFGTVADKSTMMTNNRGSAAWMAPEVFE 186 Query: 538 PRRVSQKADVFSFGVLLLELLTGKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFDMELL 359 + ++K D+FS+ ++L E+L+ K P +G+D +Q W +++ E Sbjct: 187 GSKYTEKCDIFSWAIVLWEVLSRKQPF------KGIDNAYTIQ------W--KIYKGERP 232 Query: 358 RNQSSEEQMVQLLQLAIDCVAQVPDARPTMSHVVVRIEEI 239 ++ + ++ L A C VP+ RP+M ++V + EI Sbjct: 233 PLLTTCPKRIEDLMTA--CWKTVPEDRPSMQYIVGVMHEI 270
>M3KSL_DROME (Q95UN8) Mitogen-activated protein kinase kinase kinase (EC| 2.7.11.25) (Mixed lineage kinase) (dMLK) (Protein slipper) Length = 1161 Score = 47.8 bits (112), Expect = 3e-05 Identities = 31/94 (32%), Positives = 54/94 (57%), Gaps = 10/94 (10%) Frame = -1 Query: 712 YIHSTSS-STSHGNIKSSNILLSKAYQA--------RVSDNGLATLVGSSSSGPSRAT-G 563 Y+H+ + S H ++KSSN+L+ +A + +++D GLA + ++ + T Sbjct: 251 YLHNEAPMSIIHRDLKSSNVLIYEAIEGNHLQQKTLKITDFGLAREMYNTQRMSAAGTYA 310 Query: 562 YRAPEVTDPRRVSQKADVFSFGVLLLELLTGKAP 461 + PEV S+ +DV+S+GVLL EL+TG+ P Sbjct: 311 WMPPEVISVSTYSKFSDVWSYGVLLWELITGETP 344
>MK14_PANTR (Q95NE7) Mitogen-activated protein kinase 14 (EC 2.7.11.24)| (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (Stress-activated protein kinase 2a) Length = 359 Score = 47.8 bits (112), Expect = 3e-05 Identities = 34/135 (25%), Positives = 64/135 (47%), Gaps = 1/135 (0%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATGYRAPEV-TD 539 +YIHS + H ++K SN+ +++ + ++ D GLA +G YRAPE+ + Sbjct: 138 KYIHS--ADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLN 195 Query: 538 PRRVSQKADVFSFGVLLLELLTGKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFDMELL 359 +Q D++S G ++ ELLTG+ G D +Q ++R T + + + Sbjct: 196 WMHYNQTVDIWSVGCIMAELLTGRTLF------PGTDHINQLQQIMRLTGTPPAYLINRM 249 Query: 358 RNQSSEEQMVQLLQL 314 + + + L Q+ Sbjct: 250 PSHEARNYIQSLTQM 264
>TNI3K_HUMAN (Q59H18) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 936 Score = 47.8 bits (112), Expect = 3e-05 Identities = 33/90 (36%), Positives = 50/90 (55%), Gaps = 5/90 (5%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGS-SSSGPSRATG---YRAPE 548 EY+H+ + H ++ S NILL + A V+D G + + S ++ G + APE Sbjct: 676 EYLHNLTQPIIHRDLNSHNILLYEDGHAVVADFGESRFLQSLDEDNMTKQPGNLRWMAPE 735 Query: 547 V-TDPRRVSQKADVFSFGVLLLELLTGKAP 461 V T R + KADVFS+ + L E+LTG+ P Sbjct: 736 VFTQCTRYTIKADVFSYALCLWEILTGEIP 765
>MK14B_CYPCA (Q9I958) Mitogen-activated protein kinase 14b (EC 2.7.11.24)| (Mitogen-activated protein kinase p38b) (MAP kinase p38b) (cp38b) Length = 361 Score = 47.8 bits (112), Expect = 3e-05 Identities = 27/84 (32%), Positives = 47/84 (55%), Gaps = 1/84 (1%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATGYRAPEV-TD 539 +YIHS + H ++K SN+ +++ + ++ D GLA L +G YRAPE+ + Sbjct: 140 KYIHS--ADIIHRDLKPSNLAVNEDCELKILDFGLARLTDDEMTGYVATRWYRAPEIMLN 197 Query: 538 PRRVSQKADVFSFGVLLLELLTGK 467 + D++S G ++ ELLTG+ Sbjct: 198 WMHYNMTVDIWSVGCIMAELLTGR 221
>PKN1_THETN (Q8R9T6) Probable serine/threonine-protein kinase Sps1 (EC| 2.7.11.1) Length = 625 Score = 47.8 bits (112), Expect = 3e-05 Identities = 27/86 (31%), Positives = 46/86 (53%), Gaps = 4/86 (4%) Frame = -1 Query: 706 HSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSS---SGPSRATGYR-APEVTD 539 H+ + H +IK NIL++ +V+D G+A ++ +G T Y +PE Sbjct: 124 HAHKNKIIHRDIKPQNILVTDEDVVKVTDFGIARAANGATITYTGDVIGTAYYFSPEQAK 183 Query: 538 PRRVSQKADVFSFGVLLLELLTGKAP 461 V ++ D++S G++L E+LTGK P Sbjct: 184 GSIVDERTDIYSLGIVLFEMLTGKVP 209
>SRK2_SPOLA (P42688) Tyrosine-protein kinase SRK2 (EC 2.7.10.2) (Fragment)| Length = 362 Score = 47.8 bits (112), Expect = 3e-05 Identities = 44/159 (27%), Positives = 69/159 (43%), Gaps = 12/159 (7%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGS----SSSGPSRATGYRAPEVTDPRRVSQKA 515 H ++ + NIL+ +V+D GLA L+ S ++ G + APE R S K+ Sbjct: 212 HRDLAARNILVGDNNICKVADFGLARLIVSDDYNATEGAKFPIKWTAPEAALFNRFSIKS 271 Query: 514 DVFSFGVLLLELLT-GKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFDMELLRNQSSEE 338 DV+SFG+L+ EL+T G+ P N E+L+N Sbjct: 272 DVWSFGILITELVTYGRIPYPGMSN------------------------AEVLQNLDKGY 307 Query: 337 QM-------VQLLQLAIDCVAQVPDARPTMSHVVVRIEE 242 +M L Q+ +DC + P RPT + R+E+ Sbjct: 308 RMPCPVTTPESLYQIMLDCWKRNPADRPTFEALQWRLED 346
>PKNX_STRCO (Q9XA16) Probable serine/threonine-protein kinase SCO3848 (EC| 2.7.11.1) Length = 673 Score = 47.8 bits (112), Expect = 3e-05 Identities = 29/91 (31%), Positives = 48/91 (52%), Gaps = 6/91 (6%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATG------YRA 554 EY H + H +IK +N++L++ Q +V D G+A +G S ++ Y + Sbjct: 127 EYSHR--AGIVHRDIKPANVMLTRNGQVKVMDFGIARAMGDSGMTMTQTAAVIGTAQYLS 184 Query: 553 PEVTDPRRVSQKADVFSFGVLLLELLTGKAP 461 PE +V ++D++S G LL ELLT + P Sbjct: 185 PEQAKGEQVDARSDLYSTGCLLYELLTVRPP 215
>LYN_RAT (Q07014) Tyrosine-protein kinase Lyn (EC 2.7.10.2)| Length = 511 Score = 47.8 bits (112), Expect = 3e-05 Identities = 35/129 (27%), Positives = 67/129 (51%), Gaps = 13/129 (10%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSS----SGPSRATGYRAPEVTDPRRVSQKA 515 H +++++N+L+S++ +++D GLA ++ + G + APE + + K+ Sbjct: 364 HRDLRAANVLVSESLMCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKS 423 Query: 514 DVFSFGVLLLELLT-GKAPSQSALN-------DEGVDLPRWVQSVVRSEWTSEVFD-MEL 362 DV+SFG+LL E++T GK P N +G +PR E++D M++ Sbjct: 424 DVWSFGILLYEIVTYGKIPYPGRTNADVMTALSQGYRMPR------MENCPDELYDIMKM 477 Query: 361 LRNQSSEEQ 335 +S+EE+ Sbjct: 478 CWKESAEER 486
>MK14B_BRARE (Q9DGE1) Mitogen-activated protein kinase 14b (EC 2.7.11.24)| (Mitogen-activated protein kinase p38b) (MAP kinase p38b) (zp38b) Length = 348 Score = 47.8 bits (112), Expect = 3e-05 Identities = 27/84 (32%), Positives = 47/84 (55%), Gaps = 1/84 (1%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATGYRAPEV-TD 539 +YIHS + H ++K SN+ +++ + ++ D GLA L +G YRAPE+ + Sbjct: 140 KYIHS--ADIIHRDLKPSNLAVNEDCELKILDFGLARLTDDEMTGYVATRWYRAPEIMLN 197 Query: 538 PRRVSQKADVFSFGVLLLELLTGK 467 + D++S G ++ ELLTG+ Sbjct: 198 WMHYNMTVDIWSVGCIMAELLTGR 221
>MK12_RAT (Q63538) Mitogen-activated protein kinase 12 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 6) (ERK-6) (Stress-activated protein kinase 3) (Mitogen-activated protein kinase p38 gamma) (MAP kinase p38 gamma) Length = 367 Score = 47.8 bits (112), Expect = 3e-05 Identities = 27/84 (32%), Positives = 48/84 (57%), Gaps = 1/84 (1%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATGYRAPEV-TD 539 +YIH+ + H ++K N+ +++ + ++ D GLA S +G YRAPEV + Sbjct: 142 KYIHA--AGVIHRDLKPGNLAVNEDCELKILDFGLARQADSEMTGYVVTRWYRAPEVILN 199 Query: 538 PRRVSQKADVFSFGVLLLELLTGK 467 R +Q D++S G ++ E++TGK Sbjct: 200 WMRYTQTVDIWSVGCIMAEMITGK 223
>MK12_MOUSE (O08911) Mitogen-activated protein kinase 12 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 6) (ERK-6) (Stress-activated protein kinase 3) (Mitogen-activated protein kinase p38 gamma) (MAP kinase p38 gamma) Length = 367 Score = 47.8 bits (112), Expect = 3e-05 Identities = 27/84 (32%), Positives = 48/84 (57%), Gaps = 1/84 (1%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATGYRAPEV-TD 539 +YIH+ + H ++K N+ +++ + ++ D GLA S +G YRAPEV + Sbjct: 142 KYIHA--AGVIHRDLKPGNLAVNEDCELKILDFGLARQADSEMTGYVVTRWYRAPEVILN 199 Query: 538 PRRVSQKADVFSFGVLLLELLTGK 467 R +Q D++S G ++ E++TGK Sbjct: 200 WMRYTQTVDIWSVGCIMAEMITGK 223
>YES_CANFA (Q28923) Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2)| (p61-Yes) (c-Yes) Length = 538 Score = 47.8 bits (112), Expect = 3e-05 Identities = 41/152 (26%), Positives = 71/152 (46%), Gaps = 5/152 (3%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSS----SGPSRATGYRAPEVTDPRRVSQKA 515 H +++++NIL+ + +++D GLA L+ + G + APE R + K+ Sbjct: 389 HRDLRAANILVGENLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS 448 Query: 514 DVFSFGVLLLELLT-GKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFDMELLRNQSSEE 338 DV+SFG+L EL T G+ P +N E ++ V R + Q E Sbjct: 449 DVWSFGILQTELTTKGRVPYPGMVNRE------VLEQVERG--------YRMPCPQGCPE 494 Query: 337 QMVQLLQLAIDCVAQVPDARPTMSHVVVRIEE 242 + +L+ L C + PD RPT ++ +E+ Sbjct: 495 SLHELMNL---CWKKDPDERPTFEYIQSFLED 523
>GUC2C_RAT (P23897) Heat-stable enterotoxin receptor precursor (GC-C)| (Intestinal guanylate cyclase) (EC 4.6.1.2) (STA receptor) Length = 1072 Score = 47.8 bits (112), Expect = 3e-05 Identities = 35/159 (22%), Positives = 77/159 (48%), Gaps = 1/159 (0%) Frame = -1 Query: 712 YIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATGYRAPEVTDPR 533 Y+HS+ HG +KS+N ++ +++D G +++ P + + APE Sbjct: 602 YLHSSKIEV-HGRLKSTNCVVDSRMVVKITDFGCNSIL------PPKKDLWTAPEHLRQA 654 Query: 532 RVSQKADVFSFGVLLLELLTGKAPSQS-ALNDEGVDLPRWVQSVVRSEWTSEVFDMELLR 356 +SQK DV+SF ++ E++ K + + D+ + R V + + ++ F +L Sbjct: 655 TISQKGDVYSFSIIAQEIILRKETFYTLSCRDQNEKIFR-----VENSYGTKPFRPDLFL 709 Query: 355 NQSSEEQMVQLLQLAIDCVAQVPDARPTMSHVVVRIEEI 239 ++++E+ +++ L C + P+ RP + + +I Sbjct: 710 -ETADEKELEVYLLVKSCWEEDPEKRPDFKKIESTLAKI 747
>MATK_HUMAN (P42679) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase) Length = 507 Score = 47.4 bits (111), Expect = 4e-05 Identities = 31/86 (36%), Positives = 46/86 (53%), Gaps = 1/86 (1%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATGYRAPEVTDP 536 EY+ S H ++ + NIL+S+ A+VSD GLA + APE Sbjct: 341 EYLES--KKLVHRDLAARNILVSEDLVAKVSDFGLAKAERKGLDSSRLPVKWTAPEALKH 398 Query: 535 RRVSQKADVFSFGVLLLELLT-GKAP 461 + + K+DV+SFGVLL E+ + G+AP Sbjct: 399 GKFTSKSDVWSFGVLLWEVFSYGRAP 424
>PKN6_MYXXA (P54738) Serine/threonine-protein kinase pkn6 (EC 2.7.11.1)| Length = 710 Score = 47.4 bits (111), Expect = 4e-05 Identities = 28/81 (34%), Positives = 42/81 (51%), Gaps = 7/81 (8%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATG-------YRAPEVTDPRRVS 524 H ++ NIL+S+ +V D G+A + G G TG Y PE + + Sbjct: 141 HRDVSPDNILVSRQGAVKVVDFGIAKVAGQ---GHRTLTGVVKGKVAYMPPEQLQAKAMD 197 Query: 523 QKADVFSFGVLLLELLTGKAP 461 ++ DV++ GV+L ELLTGK P Sbjct: 198 RRVDVYALGVVLYELLTGKRP 218
>KS6A6_HUMAN (Q9UK32) Ribosomal protein S6 kinase alpha-6 (EC 2.7.11.1)| (S6K-alpha 6) (90 kDa ribosomal protein S6 kinase 6) (p90-RSK 6) (Ribosomal S6 kinase 4) (RSK-4) (pp90RSK4) Length = 745 Score = 47.4 bits (111), Expect = 4e-05 Identities = 30/87 (34%), Positives = 46/87 (52%), Gaps = 3/87 (3%) Frame = -1 Query: 676 NIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATG---YRAPEVTDPRRVSQKADVF 506 ++K NILL + +++D GL+ G Y APEV + R SQ AD + Sbjct: 198 DLKPENILLDEIGHIKLTDFGLSKESVDQEKKAYSFCGTVEYMAPEVVNRRGHSQSADWW 257 Query: 505 SFGVLLLELLTGKAPSQSALNDEGVDL 425 S+GVL+ E+LTG P Q +E +++ Sbjct: 258 SYGVLMFEMLTGTLPFQGKDRNETMNM 284 Score = 37.4 bits (85), Expect = 0.046 Identities = 28/99 (28%), Positives = 42/99 (42%), Gaps = 7/99 (7%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILL----SKAYQARVSDNGLATLVGSSSS---GPSRATGYR 557 +Y+H H ++K SNIL + A R+ D G A + + P + Sbjct: 532 DYLHC--QGVVHRDLKPSNILYMDESASADSIRICDFGFAKQLRGENGLLLTPCYTANFV 589 Query: 556 APEVTDPRRVSQKADVFSFGVLLLELLTGKAPSQSALND 440 APEV + D++S GVL +L G P + ND Sbjct: 590 APEVLMQQGYDAACDIWSLGVLFYTMLAGYTPFANGPND 628
>GRK5_RAT (Q62833) G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK5) Length = 590 Score = 47.4 bits (111), Expect = 4e-05 Identities = 27/79 (34%), Positives = 41/79 (51%), Gaps = 2/79 (2%) Frame = -1 Query: 691 STSHGNIKSSNILLSKAYQARVSDNGLATLV--GSSSSGPSRATGYRAPEVTDPRRVSQK 518 +T + ++K NILL R+SD GLA + G G GY APEV + +R Sbjct: 306 NTVYRDLKPENILLDDYGHIRISDLGLAVKIPEGDLIRGRVGTVGYMAPEVLNNQRYGLS 365 Query: 517 ADVFSFGVLLLELLTGKAP 461 D + G L+ E++ G++P Sbjct: 366 PDYWGLGCLIYEMIEGQSP 384
>GRK5_MOUSE (Q8VEB1) G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK5) Length = 590 Score = 47.4 bits (111), Expect = 4e-05 Identities = 27/79 (34%), Positives = 41/79 (51%), Gaps = 2/79 (2%) Frame = -1 Query: 691 STSHGNIKSSNILLSKAYQARVSDNGLATLV--GSSSSGPSRATGYRAPEVTDPRRVSQK 518 +T + ++K NILL R+SD GLA + G G GY APEV + +R Sbjct: 306 NTVYRDLKPENILLDDYGHIRISDLGLAVKIPEGDLIRGRVGTVGYMAPEVLNNQRYGLS 365 Query: 517 ADVFSFGVLLLELLTGKAP 461 D + G L+ E++ G++P Sbjct: 366 PDYWGLGCLIYEMIEGQSP 384
>GRK5_HUMAN (P34947) G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK5) Length = 590 Score = 47.4 bits (111), Expect = 4e-05 Identities = 27/79 (34%), Positives = 41/79 (51%), Gaps = 2/79 (2%) Frame = -1 Query: 691 STSHGNIKSSNILLSKAYQARVSDNGLATLV--GSSSSGPSRATGYRAPEVTDPRRVSQK 518 +T + ++K NILL R+SD GLA + G G GY APEV + +R Sbjct: 306 NTVYRDLKPENILLDDYGHIRISDLGLAVKIPEGDLIRGRVGTVGYMAPEVLNNQRYGLS 365 Query: 517 ADVFSFGVLLLELLTGKAP 461 D + G L+ E++ G++P Sbjct: 366 PDYWGLGCLIYEMIEGQSP 384
>AURKB_PIG (Q9N0X0) Serine/threonine-protein kinase 12 (EC 2.7.11.1)| (Aurora-B) (Fragment) Length = 156 Score = 47.4 bits (111), Expect = 4e-05 Identities = 29/92 (31%), Positives = 46/92 (50%), Gaps = 1/92 (1%) Frame = -1 Query: 709 IHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRAT-GYRAPEVTDPR 533 I+ H +IK N+LL + +++D G + S R T Y PE+ + R Sbjct: 40 IYCHGKKVIHRDIKPENLLLGLQGELKIADFGWSVHAPSLRRKTMRGTLDYLPPEMIEGR 99 Query: 532 RVSQKADVFSFGVLLLELLTGKAPSQSALNDE 437 ++K D++ GVL ELL G P +SA ++E Sbjct: 100 THNEKVDLWCIGVLCYELLVGNPPFESASHNE 131
>CSK_RAT (P32577) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| Length = 450 Score = 47.4 bits (111), Expect = 4e-05 Identities = 26/75 (34%), Positives = 43/75 (57%), Gaps = 1/75 (1%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATGYRAPEVTDPRRVSQKADVFS 503 H ++ + N+L+S+ A+VSD GL S+ + APE ++ S K+DV+S Sbjct: 312 HRDLAARNVLVSEDNVAKVSDFGLTKEASSTQDTGKLPVKWTAPEALREKKFSTKSDVWS 371 Query: 502 FGVLLLELLT-GKAP 461 FG+LL E+ + G+ P Sbjct: 372 FGILLWEIYSFGRVP 386
>CSK_MOUSE (P41241) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| (Protein-tyrosine kinase MPK-2) (p50CSK) Length = 450 Score = 47.4 bits (111), Expect = 4e-05 Identities = 26/75 (34%), Positives = 43/75 (57%), Gaps = 1/75 (1%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATGYRAPEVTDPRRVSQKADVFS 503 H ++ + N+L+S+ A+VSD GL S+ + APE ++ S K+DV+S Sbjct: 312 HRDLAARNVLVSEDNVAKVSDFGLTKEASSTQDTGKLPVKWTAPEALREKKFSTKSDVWS 371 Query: 502 FGVLLLELLT-GKAP 461 FG+LL E+ + G+ P Sbjct: 372 FGILLWEIYSFGRVP 386
>CSK_HUMAN (P41240) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| (Protein-tyrosine kinase CYL) Length = 450 Score = 47.4 bits (111), Expect = 4e-05 Identities = 26/75 (34%), Positives = 43/75 (57%), Gaps = 1/75 (1%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATGYRAPEVTDPRRVSQKADVFS 503 H ++ + N+L+S+ A+VSD GL S+ + APE ++ S K+DV+S Sbjct: 312 HRDLAARNVLVSEDNVAKVSDFGLTKEASSTQDTGKLPVKWTAPEALREKKFSTKSDVWS 371 Query: 502 FGVLLLELLT-GKAP 461 FG+LL E+ + G+ P Sbjct: 372 FGILLWEIYSFGRVP 386
>TNI3K_MOUSE (Q5GIG6) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 833 Score = 47.4 bits (111), Expect = 4e-05 Identities = 34/90 (37%), Positives = 49/90 (54%), Gaps = 5/90 (5%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGS-SSSGPSRATG---YRAPE 548 EY+HS + H ++ S NILL + A V+D G + + S ++ G + APE Sbjct: 573 EYLHSLTQPIIHRDLNSHNILLYEDGHAVVADFGESRFLQSLDEDNMTKQPGNLRWMAPE 632 Query: 547 V-TDPRRVSQKADVFSFGVLLLELLTGKAP 461 V T R + KADVFS+ + L ELL G+ P Sbjct: 633 VFTQCTRYTIKADVFSYALCLWELLIGEIP 662
>SRC_RSVSE (P63185) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 47.4 bits (111), Expect = 4e-05 Identities = 31/90 (34%), Positives = 49/90 (54%), Gaps = 5/90 (5%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSS----SGPSRATGYRAPEVTDPRRVSQKA 515 H +++++NIL+ + +V+D GLA L+ + G + APE R + K+ Sbjct: 383 HRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS 442 Query: 514 DVFSFGVLLLELLT-GKAPSQSALNDEGVD 428 DV+SFG+LL EL T G+ P N E +D Sbjct: 443 DVWSFGILLTELTTKGRVPYPGMGNGEVLD 472
>SRC_RSVSA (P00524) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 47.4 bits (111), Expect = 4e-05 Identities = 31/90 (34%), Positives = 49/90 (54%), Gaps = 5/90 (5%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSS----SGPSRATGYRAPEVTDPRRVSQKA 515 H +++++NIL+ + +V+D GLA L+ + G + APE R + K+ Sbjct: 383 HRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS 442 Query: 514 DVFSFGVLLLELLT-GKAPSQSALNDEGVD 428 DV+SFG+LL EL T G+ P N E +D Sbjct: 443 DVWSFGILLTELTTKGRVPYPGMGNGEVLD 472
>SRC_AVISR (P00525) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 47.4 bits (111), Expect = 4e-05 Identities = 31/90 (34%), Positives = 49/90 (54%), Gaps = 5/90 (5%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSS----SGPSRATGYRAPEVTDPRRVSQKA 515 H +++++NIL+ + +V+D GLA L+ + G + APE R + K+ Sbjct: 383 HRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS 442 Query: 514 DVFSFGVLLLELLT-GKAPSQSALNDEGVD 428 DV+SFG+LL EL T G+ P N E +D Sbjct: 443 DVWSFGILLTELTTKGRVPYPGMGNGEVLD 472
>FGR_FSVGR (P00544) Tyrosine-protein kinase transforming protein Fgr (EC| 2.7.10.2) Length = 545 Score = 47.4 bits (111), Expect = 4e-05 Identities = 28/87 (32%), Positives = 49/87 (56%), Gaps = 5/87 (5%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATGY----RAPEVTDPRRVSQKA 515 H +++++NIL+ + +++D GLA L+ + P + + APE R + K+ Sbjct: 403 HRDLRAANILVGERLVCKIADFGLARLIEDNEYNPRQGAKFPIKWTAPEAALFGRFTIKS 462 Query: 514 DVFSFGVLLLELLT-GKAPSQSALNDE 437 DV+SFG+LL EL++ G+ P N E Sbjct: 463 DVWSFGILLTELISKGRVPYPGMNNRE 489
>HOG1_CANAL (Q92207) Mitogen-activated protein kinase HOG1 (EC 2.7.11.24) (MAP| kinase HOG1) Length = 377 Score = 47.4 bits (111), Expect = 4e-05 Identities = 28/84 (33%), Positives = 47/84 (55%), Gaps = 1/84 (1%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATGYRAPEV-TD 539 +YIHS + H ++K SNIL+++ ++ D GLA L +G YRAPE+ Sbjct: 133 KYIHS--AGVIHRDLKPSNILINENCDLKICDFGLARLQDPQMTGYVSTRYYRAPEIMLT 190 Query: 538 PRRVSQKADVFSFGVLLLELLTGK 467 ++ + D++S G +L E++ GK Sbjct: 191 WQKYDTEVDLWSVGCILAEMIEGK 214
>MK12_HUMAN (P53778) Mitogen-activated protein kinase 12 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 6) (ERK-6) (ERK5) (Stress-activated protein kinase 3) (Mitogen-activated protein kinase p38 gamma) (MAP kinase p38 gamma) Length = 367 Score = 47.0 bits (110), Expect = 6e-05 Identities = 27/83 (32%), Positives = 47/83 (56%), Gaps = 1/83 (1%) Frame = -1 Query: 712 YIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATGYRAPEV-TDP 536 YIH+ + H ++K N+ +++ + ++ D GLA S +G YRAPEV + Sbjct: 143 YIHA--AGIIHRDLKPGNLAVNEDCELKILDFGLARQADSEMTGYVVTRWYRAPEVILNW 200 Query: 535 RRVSQKADVFSFGVLLLELLTGK 467 R +Q D++S G ++ E++TGK Sbjct: 201 MRYTQTVDIWSVGCIMAEMITGK 223
>MP2K7_HUMAN (O14733) Dual specificity mitogen-activated protein kinase kinase 7| (EC 2.7.12.2) (MAP kinase kinase 7) (MAPKK 7) (MAPK/ERK kinase 7) (JNK-activating kinase 2) (c-Jun N-terminal kinase kinase 2) (JNK kinase 2) (JNKK 2) Length = 419 Score = 47.0 bits (110), Expect = 6e-05 Identities = 32/88 (36%), Positives = 49/88 (55%), Gaps = 7/88 (7%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLA-TLVGSSSSGPSRA-TGYRAPEVTDPRRVSQ---- 521 H ++K SNILL + Q ++ D G++ LV S + S Y APE DP ++ Sbjct: 241 HRDVKPSNILLDERGQIKLCDFGISGRLVDSKAKTRSAGCAAYMAPERIDPPDPTKPDYD 300 Query: 520 -KADVFSFGVLLLELLTGKAPSQSALND 440 +ADV+S G+ L+EL TG+ P ++ D Sbjct: 301 IRADVWSLGISLVELATGQFPYKNCKTD 328
>MK14_XENLA (P47812) Mitogen-activated protein kinase 14 (EC 2.7.11.24)| (Mitogen-activated Mitogen-activated protein kinase 2) (MAP kinase 2) (MPK2) Length = 361 Score = 47.0 bits (110), Expect = 6e-05 Identities = 27/84 (32%), Positives = 47/84 (55%), Gaps = 1/84 (1%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATGYRAPEV-TD 539 +YIHS + H ++K SN+ +++ + ++ D GLA +G YRAPE+ + Sbjct: 140 KYIHS--AGIIHRDLKPSNLAVNEDCELKILDFGLARHTDEEMTGYVATRWYRAPEIMLN 197 Query: 538 PRRVSQKADVFSFGVLLLELLTGK 467 +Q D++S G ++ ELLTG+ Sbjct: 198 WMHYNQTVDIWSVGCIMAELLTGR 221
>CSK_CHICK (P41239) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| Length = 450 Score = 47.0 bits (110), Expect = 6e-05 Identities = 26/75 (34%), Positives = 43/75 (57%), Gaps = 1/75 (1%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATGYRAPEVTDPRRVSQKADVFS 503 H ++ + N+L+S+ A+VSD GL S+ + APE ++ S K+DV+S Sbjct: 312 HRDLAARNVLVSEDNIAKVSDFGLTKEASSTQDTGKLPVKWTAPEALREKKFSTKSDVWS 371 Query: 502 FGVLLLELLT-GKAP 461 FG+LL E+ + G+ P Sbjct: 372 FGILLWEIYSFGRVP 386
>PAK3_RAT (Q62829) Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1)| (p21-activated kinase 3) (PAK-3) (Beta-PAK) (p65-PAK) Length = 544 Score = 47.0 bits (110), Expect = 6e-05 Identities = 26/88 (29%), Positives = 45/88 (51%), Gaps = 3/88 (3%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATG---YRAPEV 545 +++HS + H +IKS NILL +++D G + S S G + APEV Sbjct: 376 DFLHS--NQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEV 433 Query: 544 TDPRRVSQKADVFSFGVLLLELLTGKAP 461 + K D++S G++ +E++ G+ P Sbjct: 434 VTRKAYGPKVDIWSLGIMAIEMVEGEPP 461
>PAK2_RAT (Q64303) Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1)| (p21-activated kinase 2) (PAK-2) (Gamma-PAK) (p62-PAK) Length = 524 Score = 47.0 bits (110), Expect = 6e-05 Identities = 25/88 (28%), Positives = 45/88 (51%), Gaps = 3/88 (3%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATG---YRAPEV 545 E++H+ + H +IKS N+LL +++D G + S S G + APEV Sbjct: 357 EFLHA--NQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEV 414 Query: 544 TDPRRVSQKADVFSFGVLLLELLTGKAP 461 + K D++S G++ +E++ G+ P Sbjct: 415 VTRKAYGPKVDIWSLGIMAIEMVEGEPP 442
>PAK2_RABIT (Q29502) Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1)| (p21-activated kinase 2) (PAK-2) (Gamma-PAK) (p21-activated protein kinase I) (PAKI) Length = 524 Score = 47.0 bits (110), Expect = 6e-05 Identities = 25/88 (28%), Positives = 45/88 (51%), Gaps = 3/88 (3%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATG---YRAPEV 545 E++H+ + H +IKS N+LL +++D G + S S G + APEV Sbjct: 357 EFLHA--NQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEV 414 Query: 544 TDPRRVSQKADVFSFGVLLLELLTGKAP 461 + K D++S G++ +E++ G+ P Sbjct: 415 VTRKAYGPKVDIWSLGIMAIEMVEGEPP 442
>PAK2_MOUSE (Q8CIN4) Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1)| (p21-activated kinase 2) (PAK-2) Length = 524 Score = 47.0 bits (110), Expect = 6e-05 Identities = 25/88 (28%), Positives = 45/88 (51%), Gaps = 3/88 (3%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATG---YRAPEV 545 E++H+ + H +IKS N+LL +++D G + S S G + APEV Sbjct: 357 EFLHA--NQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEV 414 Query: 544 TDPRRVSQKADVFSFGVLLLELLTGKAP 461 + K D++S G++ +E++ G+ P Sbjct: 415 VTRKAYGPKVDIWSLGIMAIEMVEGEPP 442
>PAK2_HUMAN (Q13177) Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1)| (p21-activated kinase 2) (PAK-2) (PAK65) (Gamma-PAK) (S6/H4 kinase) Length = 524 Score = 47.0 bits (110), Expect = 6e-05 Identities = 25/88 (28%), Positives = 45/88 (51%), Gaps = 3/88 (3%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATG---YRAPEV 545 E++H+ + H +IKS N+LL +++D G + S S G + APEV Sbjct: 357 EFLHA--NQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEV 414 Query: 544 TDPRRVSQKADVFSFGVLLLELLTGKAP 461 + K D++S G++ +E++ G+ P Sbjct: 415 VTRKAYGPKVDIWSLGIMAIEMVEGEPP 442
>SHK1_SCHPO (P50527) Serine/threonine-protein kinase pak1/shk1 (EC 2.7.11.1)| Length = 658 Score = 47.0 bits (110), Expect = 6e-05 Identities = 26/85 (30%), Positives = 44/85 (51%), Gaps = 3/85 (3%) Frame = -1 Query: 706 HSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATG---YRAPEVTDP 536 H + H +IKS NILLS +++D G + S+ + + G + APEV Sbjct: 495 HLHENGIVHRDIKSDNILLSLQGDIKLTDFGFCAQIDSNMTKRTTMVGTPYWMAPEVVTR 554 Query: 535 RRVSQKADVFSFGVLLLELLTGKAP 461 + K DV+S G++ +E++ G+ P Sbjct: 555 KEYGFKVDVWSLGIMAIEMVEGEPP 579
>PKNB_MYCLE (P54744) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 622 Score = 47.0 bits (110), Expect = 6e-05 Identities = 26/79 (32%), Positives = 42/79 (53%), Gaps = 5/79 (6%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRAT-----GYRAPEVTDPRRVSQK 518 H ++K +NI++S +V D G+A + S+S A Y +PE V + Sbjct: 136 HRDVKPANIMISATNAVKVMDFGIARAIADSTSVTQTAAVIGTAQYLSPEQARGDSVDAR 195 Query: 517 ADVFSFGVLLLELLTGKAP 461 +DV+S G +L E+LTG+ P Sbjct: 196 SDVYSLGCVLYEILTGEPP 214
>M3K1_ARATH (O22040) Mitogen-activated protein kinase kinase kinase 1 (EC| 2.7.11.25) (Arabidospsis NPK1-related protein kinase 1) Length = 666 Score = 47.0 bits (110), Expect = 6e-05 Identities = 46/166 (27%), Positives = 74/166 (44%), Gaps = 13/166 (7%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNG-------LATLVGSSSSGPSRATGY- 560 EY+H+ + H +IK +NIL+ +++D G LAT+ G+ S + T Y Sbjct: 186 EYLHN--HAIMHRDIKGANILVDNKGCIKLADFGASKQVAELATMTGAKSM---KGTPYW 240 Query: 559 RAPEVTDPRRVSQKADVFSFGVLLLELLTGKAPSQSALNDEGVDLPRWVQSVVRSEWTSE 380 APEV S AD++S G ++E++TGKAP W S+ E Sbjct: 241 MAPEVILQTGHSFSADIWSVGCTVIEMVTGKAP--------------W------SQQYKE 280 Query: 379 VFDMELLRNQSSEEQMVQLL-----QLAIDCVAQVPDARPTMSHVV 257 V + + S + L + C+ +VP+ RPT S ++ Sbjct: 281 VAAIFFIGTTKSHPPIPDTLSSDAKDFLLKCLQEVPNLRPTASELL 326
>GRK6_RAT (P97711) G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK6) Length = 576 Score = 47.0 bits (110), Expect = 6e-05 Identities = 28/76 (36%), Positives = 39/76 (51%), Gaps = 2/76 (2%) Frame = -1 Query: 676 NIKSSNILLSKAYQARVSDNGLATLV--GSSSSGPSRATGYRAPEVTDPRRVSQKADVFS 503 ++K NILL R+SD GL V G + G GY APEV R + D ++ Sbjct: 311 DLKPENILLDDHGHIRISDLGLTVHVPEGQTIKGRVGTVGYMAPEVVKNERYTFSPDWWA 370 Query: 502 FGVLLLELLTGKAPSQ 455 G LL E++ G++P Q Sbjct: 371 LGCLLYEMIAGQSPFQ 386
>BLK_MOUSE (P16277) Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte| kinase) (p55-BLK) Length = 498 Score = 47.0 bits (110), Expect = 6e-05 Identities = 29/86 (33%), Positives = 49/86 (56%), Gaps = 4/86 (4%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGS---SSSGPSRATGYRAPEVTDPRRVSQKAD 512 H +++++NIL+S+ +++D GLA ++ S + G + APE + KAD Sbjct: 351 HRDLRAANILVSETLCCKIADFGLARIIDSEYTAQEGAKFPIKWTAPEAIHFGVFTIKAD 410 Query: 511 VFSFGVLLLELLT-GKAPSQSALNDE 437 V+SFGVLL+ ++T G+ P N E Sbjct: 411 VWSFGVLLMVIVTYGRVPYPGMSNPE 436
>PAK3_PONPY (Q7YQL3) Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1)| (p21-activated kinase 3) (PAK-3) Length = 559 Score = 47.0 bits (110), Expect = 6e-05 Identities = 26/88 (29%), Positives = 45/88 (51%), Gaps = 3/88 (3%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATG---YRAPEV 545 +++HS + H +IKS NILL +++D G + S S G + APEV Sbjct: 391 DFLHS--NQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEV 448 Query: 544 TDPRRVSQKADVFSFGVLLLELLTGKAP 461 + K D++S G++ +E++ G+ P Sbjct: 449 VTRKAYGPKVDIWSLGIMAIEMVEGEPP 476
>PAK3_PANTR (Q7YQL4) Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1)| (p21-activated kinase 3) (PAK-3) Length = 559 Score = 47.0 bits (110), Expect = 6e-05 Identities = 26/88 (29%), Positives = 45/88 (51%), Gaps = 3/88 (3%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATG---YRAPEV 545 +++HS + H +IKS NILL +++D G + S S G + APEV Sbjct: 391 DFLHS--NQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEV 448 Query: 544 TDPRRVSQKADVFSFGVLLLELLTGKAP 461 + K D++S G++ +E++ G+ P Sbjct: 449 VTRKAYGPKVDIWSLGIMAIEMVEGEPP 476
>PAK3_MOUSE (Q61036) Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1)| (p21-activated kinase 3) (PAK-3) (Beta-PAK) (CDC42/RAC effector kinase PAK-B) Length = 559 Score = 47.0 bits (110), Expect = 6e-05 Identities = 26/88 (29%), Positives = 45/88 (51%), Gaps = 3/88 (3%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATG---YRAPEV 545 +++HS + H +IKS NILL +++D G + S S G + APEV Sbjct: 391 DFLHS--NQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEV 448 Query: 544 TDPRRVSQKADVFSFGVLLLELLTGKAP 461 + K D++S G++ +E++ G+ P Sbjct: 449 VTRKAYGPKVDIWSLGIMAIEMVEGEPP 476
>PAK3_HUMAN (O75914) Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1)| (p21-activated kinase 3) (PAK-3) (Beta-PAK) (Oligophrenin-3) Length = 559 Score = 47.0 bits (110), Expect = 6e-05 Identities = 26/88 (29%), Positives = 45/88 (51%), Gaps = 3/88 (3%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATG---YRAPEV 545 +++HS + H +IKS NILL +++D G + S S G + APEV Sbjct: 391 DFLHS--NQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEV 448 Query: 544 TDPRRVSQKADVFSFGVLLLELLTGKAP 461 + K D++S G++ +E++ G+ P Sbjct: 449 VTRKAYGPKVDIWSLGIMAIEMVEGEPP 476
>ANPRA_HUMAN (P16066) Atrial natriuretic peptide receptor A precursor (ANP-A)| (ANPRA) (GC-A) (Guanylate cyclase) (EC 4.6.1.2) (NPR-A) (Atrial natriuretic peptide A-type receptor) Length = 1061 Score = 47.0 bits (110), Expect = 6e-05 Identities = 45/151 (29%), Positives = 70/151 (46%), Gaps = 9/151 (5%) Frame = -1 Query: 685 SHGNIKSSNILLSKAYQARVSDNGLAT---LVGSSSSGPSRATGYRAPEV----TDPRRV 527 SHGN+KSSN ++ + +++D GL + L + APE+ + P R Sbjct: 657 SHGNLKSSNCVVDGRFVLKITDYGLESFRDLDPEQGHTVYAKKLWTAPELLRMASPPVRG 716 Query: 526 SQKADVFSFGVLLLELLTGKAPSQSALNDEGVDL--PRWVQSVVRSEWTSEVFDMELLRN 353 SQ DV+SFG++L E+ A + EG+DL ++ V R E + L Sbjct: 717 SQAGDVYSFGIILQEI----ALRSGVFHVEGLDLSPKEIIERVTRGEQPPFRPSLAL--- 769 Query: 352 QSSEEQMVQLLQLAIDCVAQVPDARPTMSHV 260 QS E++ L+Q C A+ P RP + Sbjct: 770 QSHLEELGLLMQ---RCWAEDPQERPPFQQI 797
>MK14_RAT (P70618) Mitogen-activated protein kinase 14 (EC 2.7.11.24)| (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (CRK1) Length = 359 Score = 47.0 bits (110), Expect = 6e-05 Identities = 27/84 (32%), Positives = 47/84 (55%), Gaps = 1/84 (1%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATGYRAPEV-TD 539 +YIHS + H ++K SN+ +++ + ++ D GLA +G YRAPE+ + Sbjct: 138 KYIHS--ADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLN 195 Query: 538 PRRVSQKADVFSFGVLLLELLTGK 467 +Q D++S G ++ ELLTG+ Sbjct: 196 WMHYNQTVDIWSVGCIMAELLTGR 219
>MK14_MOUSE (P47811) Mitogen-activated protein kinase 14 (EC 2.7.11.24)| (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (CRK1) Length = 359 Score = 47.0 bits (110), Expect = 6e-05 Identities = 27/84 (32%), Positives = 47/84 (55%), Gaps = 1/84 (1%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATGYRAPEV-TD 539 +YIHS + H ++K SN+ +++ + ++ D GLA +G YRAPE+ + Sbjct: 138 KYIHS--ADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLN 195 Query: 538 PRRVSQKADVFSFGVLLLELLTGK 467 +Q D++S G ++ ELLTG+ Sbjct: 196 WMHYNQTVDIWSVGCIMAELLTGR 219
>MK14_HUMAN (Q16539) Mitogen-activated protein kinase 14 (EC 2.7.11.24)| (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (Cytokine suppressive anti-inflammatory drug-binding protein) (CSAID-binding protein) (CSBP) (MAX-interacting prote Length = 359 Score = 47.0 bits (110), Expect = 6e-05 Identities = 27/84 (32%), Positives = 47/84 (55%), Gaps = 1/84 (1%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATGYRAPEV-TD 539 +YIHS + H ++K SN+ +++ + ++ D GLA +G YRAPE+ + Sbjct: 138 KYIHS--ADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLN 195 Query: 538 PRRVSQKADVFSFGVLLLELLTGK 467 +Q D++S G ++ ELLTG+ Sbjct: 196 WMHYNQTVDIWSVGCIMAELLTGR 219
>MK14_CANFA (O02812) Mitogen-activated protein kinase 14 (EC 2.7.11.24)| (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) Length = 359 Score = 47.0 bits (110), Expect = 6e-05 Identities = 27/84 (32%), Positives = 47/84 (55%), Gaps = 1/84 (1%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATGYRAPEV-TD 539 +YIHS + H ++K SN+ +++ + ++ D GLA +G YRAPE+ + Sbjct: 138 KYIHS--ADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLN 195 Query: 538 PRRVSQKADVFSFGVLLLELLTGK 467 +Q D++S G ++ ELLTG+ Sbjct: 196 WMHYNQTVDIWSVGCIMAELLTGR 219
>MST4_MOUSE (Q99JT2) Serine/threonine-protein kinase MST4 (EC 2.7.11.1)| (STE20-like kinase MST4) (MST-4) (Mammalian STE20-like protein kinase 4) Length = 416 Score = 47.0 bits (110), Expect = 6e-05 Identities = 27/89 (30%), Positives = 48/89 (53%), Gaps = 3/89 (3%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATG---YRAPEV 545 +Y+HS H +IK++N+LLS+ +++D G+A + + + G + APEV Sbjct: 133 DYLHSEKKI--HRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEV 190 Query: 544 TDPRRVSQKADVFSFGVLLLELLTGKAPS 458 KAD++S G+ +EL G+ P+ Sbjct: 191 IQQSAYDSKADIWSLGITAIELAKGEPPN 219
>MST4_HUMAN (Q9P289) Serine/threonine-protein kinase MST4 (EC 2.7.11.1)| (STE20-like kinase MST4) (MST-4) (Mammalian STE20-like protein kinase 4) (Serine/threonine-protein kinase MASK) (Mst3 and SOK1-related kinase) Length = 416 Score = 47.0 bits (110), Expect = 6e-05 Identities = 27/89 (30%), Positives = 48/89 (53%), Gaps = 3/89 (3%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATG---YRAPEV 545 +Y+HS H +IK++N+LLS+ +++D G+A + + + G + APEV Sbjct: 133 DYLHSEKKI--HRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEV 190 Query: 544 TDPRRVSQKADVFSFGVLLLELLTGKAPS 458 KAD++S G+ +EL G+ P+ Sbjct: 191 IQQSAYDSKADIWSLGITAIELAKGEPPN 219
>STK24_HUMAN (Q9Y6E0) Serine/threonine-protein kinase 24 (EC 2.7.11.1)| (STE20-like kinase MST3) (MST-3) (Mammalian STE20-like protein kinase 3) Length = 443 Score = 46.6 bits (109), Expect = 8e-05 Identities = 27/88 (30%), Positives = 48/88 (54%), Gaps = 3/88 (3%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATG---YRAPEV 545 +Y+HS H +IK++N+LLS+ + +++D G+A + + + G + APEV Sbjct: 145 DYLHSEKKI--HRDIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEV 202 Query: 544 TDPRRVSQKADVFSFGVLLLELLTGKAP 461 KAD++S G+ +EL G+ P Sbjct: 203 IKQSAYDSKADIWSLGITAIELARGEPP 230
>STK6_HUMAN (O14965) Serine/threonine-protein kinase 6 (EC 2.7.11.1)| (Serine/threonine kinase 15) (Aurora/IPL1-related kinase 1) (Aurora-related kinase 1) (hARK1) (Aurora-A) (Breast-tumor-amplified kinase) Length = 403 Score = 46.6 bits (109), Expect = 8e-05 Identities = 30/88 (34%), Positives = 44/88 (50%), Gaps = 1/88 (1%) Frame = -1 Query: 712 YIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRAT-GYRAPEVTDP 536 Y HS H +IK N+LL A + +++D G + SS T Y PE+ + Sbjct: 246 YCHS--KRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEMIEG 303 Query: 535 RRVSQKADVFSFGVLLLELLTGKAPSQS 452 R +K D++S GVL E L GK P ++ Sbjct: 304 RMHDEKVDLWSLGVLCYEFLVGKPPFEA 331
>STK24_MOUSE (Q99KH8) Serine/threonine-protein kinase 24 (EC 2.7.11.1)| Length = 431 Score = 46.6 bits (109), Expect = 8e-05 Identities = 27/88 (30%), Positives = 48/88 (54%), Gaps = 3/88 (3%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATG---YRAPEV 545 +Y+HS H +IK++N+LLS+ + +++D G+A + + + G + APEV Sbjct: 133 DYLHSEKKI--HRDIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEV 190 Query: 544 TDPRRVSQKADVFSFGVLLLELLTGKAP 461 KAD++S G+ +EL G+ P Sbjct: 191 IKQSAYDSKADIWSLGITAIELAKGEPP 218
>BMX_MOUSE (P97504) Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2)| (Bone marrow tyrosine kinase gene in chromosome X protein homolog) Length = 651 Score = 46.6 bits (109), Expect = 8e-05 Identities = 39/154 (25%), Positives = 66/154 (42%), Gaps = 5/154 (3%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGS----SSSGPSRATGYRAPEVTDPRRVSQKA 515 H ++ + N L+ +VSD G+ V SS G + APEV + S K+ Sbjct: 510 HRDLAARNCLVDSDLSVKVSDFGMTRYVLDDQYVSSVGTKFPVKWSAPEVFHYFKYSSKS 569 Query: 514 DVFSFGVLLLELLT-GKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFDMELLRNQSSEE 338 DV++FG+L+ E+ + GK P N E V + R + S+ Sbjct: 570 DVWAFGILMWEVFSLGKQPYDLYDNSEVVVKVSQGHRLYRPQLASDT------------- 616 Query: 337 QMVQLLQLAIDCVAQVPDARPTMSHVVVRIEEIK 236 + Q+ C ++P+ RPT ++ IE ++ Sbjct: 617 ----IYQIMYSCWHELPEKRPTFQQLLSAIEPLR 646
>KS6A3_MOUSE (P18654) Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1)| (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (MAP kinase-activated protein kinase 1b) (MAPKAPK1B) Length = 740 Score = 46.6 bits (109), Expect = 8e-05 Identities = 31/87 (35%), Positives = 44/87 (50%), Gaps = 3/87 (3%) Frame = -1 Query: 706 HSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATG---YRAPEVTDP 536 H S + ++K NILL + +++D GL+ G Y APEV + Sbjct: 183 HLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNR 242 Query: 535 RRVSQKADVFSFGVLLLELLTGKAPSQ 455 R +Q AD +SFGVL+ E+LTG P Q Sbjct: 243 RGHTQSADWWSFGVLMFEMLTGTLPFQ 269 Score = 39.7 bits (91), Expect = 0.009 Identities = 29/99 (29%), Positives = 44/99 (44%), Gaps = 7/99 (7%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILL----SKAYQARVSDNGLATLVGSSSS---GPSRATGYR 557 EY+H+ H ++K SNIL R+ D G A + + + P + Sbjct: 528 EYLHA--QGVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFV 585 Query: 556 APEVTDPRRVSQKADVFSFGVLLLELLTGKAPSQSALND 440 APEV + D++S GVLL +LTG P + +D Sbjct: 586 APEVLKRQGYDAACDIWSLGVLLYTMLTGYTPFANGPDD 624
>KS6A3_HUMAN (P51812) Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1)| (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protei Length = 740 Score = 46.6 bits (109), Expect = 8e-05 Identities = 31/87 (35%), Positives = 44/87 (50%), Gaps = 3/87 (3%) Frame = -1 Query: 706 HSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATG---YRAPEVTDP 536 H S + ++K NILL + +++D GL+ G Y APEV + Sbjct: 183 HLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNR 242 Query: 535 RRVSQKADVFSFGVLLLELLTGKAPSQ 455 R +Q AD +SFGVL+ E+LTG P Q Sbjct: 243 RGHTQSADWWSFGVLMFEMLTGTLPFQ 269 Score = 39.7 bits (91), Expect = 0.009 Identities = 29/99 (29%), Positives = 44/99 (44%), Gaps = 7/99 (7%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILL----SKAYQARVSDNGLATLVGSSSS---GPSRATGYR 557 EY+H+ H ++K SNIL R+ D G A + + + P + Sbjct: 528 EYLHA--QGVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFV 585 Query: 556 APEVTDPRRVSQKADVFSFGVLLLELLTGKAPSQSALND 440 APEV + D++S GVLL +LTG P + +D Sbjct: 586 APEVLKRQGYDAACDIWSLGVLLYTMLTGYTPFANGPDD 624
>CLA4_CANAL (O14427) Serine/threonine-protein kinase CLA4 (EC 2.7.11.1)| Length = 971 Score = 46.6 bits (109), Expect = 8e-05 Identities = 31/113 (27%), Positives = 55/113 (48%), Gaps = 3/113 (2%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATG---YRAPEVTDPRRVSQKAD 512 H +IKS N+LL +++D G + + + G + APEV + +K D Sbjct: 801 HRDIKSDNVLLDAYGNVKITDFGFCAKLTDQRNKRATMVGTPYWMAPEVVKQKEYDEKVD 860 Query: 511 VFSFGVLLLELLTGKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFDMELLRN 353 V+S G++ +E++ G+ P LN+E P ++ + T ++ ELL N Sbjct: 861 VWSLGIMTIEMIEGEPP---YLNEE----PLKALYLIATNGTPKLKKPELLSN 906
>NEK8_MOUSE (Q91ZR4) Serine/threonine-protein kinase Nek8 (EC 2.7.11.1) (Never| in mitosis A-related kinase 8) (NimA-related protein kinase 8) Length = 698 Score = 46.6 bits (109), Expect = 8e-05 Identities = 35/147 (23%), Positives = 71/147 (48%), Gaps = 3/147 (2%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQA-RVSDNGLATLVGSSSSGPS--RATGYRAPEVTDPRRVSQKAD 512 H ++K+ NILL K ++ D G++ ++ S S + Y +PE+ + + +QK+D Sbjct: 126 HRDLKTQNILLDKHRMVVKIGDFGISKILSSKSKAYTVVGTPCYISPELCEGKPYNQKSD 185 Query: 511 VFSFGVLLLELLTGKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFDMELLRNQSSEEQM 332 +++ G +L EL + K ++A +LP V ++ + S+ Sbjct: 186 IWALGCVLYELASLKRAFEAA------NLPALVLKIMSGTFA-----------PISDRYS 228 Query: 331 VQLLQLAIDCVAQVPDARPTMSHVVVR 251 +L QL + ++ P RP +SH++ + Sbjct: 229 PELRQLVLSLLSLEPAQRPPLSHIMAQ 255
>NEK8_HUMAN (Q86SG6) Serine/threonine-protein kinase Nek8 (EC 2.7.11.1) (Never| in mitosis A-related kinase 8) (NimA-related protein kinase 8) (NIMA-related kinase 12a) Length = 692 Score = 46.6 bits (109), Expect = 8e-05 Identities = 35/147 (23%), Positives = 71/147 (48%), Gaps = 3/147 (2%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQA-RVSDNGLATLVGSSSSGPS--RATGYRAPEVTDPRRVSQKAD 512 H ++K+ NILL K ++ D G++ ++ S S + Y +PE+ + + +QK+D Sbjct: 126 HRDLKTQNILLDKHRMVVKIGDFGISKILSSKSKAYTVVGTPCYISPELCEGKPYNQKSD 185 Query: 511 VFSFGVLLLELLTGKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFDMELLRNQSSEEQM 332 +++ G +L EL + K ++A +LP V ++ + S+ Sbjct: 186 IWALGCVLYELASLKRAFEAA------NLPALVLKIMSGTFA-----------PISDRYS 228 Query: 331 VQLLQLAIDCVAQVPDARPTMSHVVVR 251 +L QL + ++ P RP +SH++ + Sbjct: 229 PELRQLVLSLLSLEPAQRPPLSHIMAQ 255
>TESK2_RAT (Q924U5) Dual specificity testis-specific protein kinase 2 (EC| 2.7.12.1) (Testicular protein kinase 2) Length = 570 Score = 46.6 bits (109), Expect = 8e-05 Identities = 43/161 (26%), Positives = 72/161 (44%), Gaps = 13/161 (8%) Frame = -1 Query: 682 HGNIKSSNILLSK---AYQARVSDNGLATLVGSSSSGPSR-----ATGYRAPEVTDPRRV 527 H ++ S N L+ + Y A V+D GLA + +S G + + + APEV Sbjct: 174 HRDLTSKNCLIKRDENGYSAVVADFGLAEKIPDASIGSEKLAVVGSPFWMAPEVLRDEPY 233 Query: 526 SQKADVFSFGVLLLELLTGKAPSQSALNDEGVDLPRWVQSVVRSEWTSEVFDMELLRNQS 347 ++KADVFS+G++L E++ + + + LPR +E F ++ Sbjct: 234 NEKADVFSYGIILCEII-------ARIQADPDYLPR-----------TENFGLD----YD 271 Query: 346 SEEQMV-----QLLQLAIDCVAQVPDARPTMSHVVVRIEEI 239 + + MV LQL +C P RP+ + +EEI Sbjct: 272 AFQHMVGDCPSDFLQLTFNCCNMDPKLRPSFEEIGKTLEEI 312
>OXSR1_PONPY (Q5R495) Serine/threonine-protein kinase OSR1 (EC 2.7.11.1)| (Oxidative stress-responsive 1 protein) Length = 527 Score = 46.6 bits (109), Expect = 8e-05 Identities = 46/172 (26%), Positives = 76/172 (44%), Gaps = 19/172 (11%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLV---GSSSSGPSRATG-----Y 560 EY+H H ++K+ NILL + +++D G++ + G + R T + Sbjct: 135 EYLHKNGQI--HRDVKAGNILLGEDGSVQIADFGVSAFLATGGDITRNKVRKTFVGTPCW 192 Query: 559 RAPEVTDP-RRVSQKADVFSFGVLLLELLTGKAPSQS---------ALNDEGVDLPRWVQ 410 APEV + R KAD++SFG+ +EL TG AP L ++ L VQ Sbjct: 193 MAPEVMEQVRGYDFKADIWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPSLETGVQ 252 Query: 409 SVVRSEWTSEVFDMELLRNQ-SSEEQMVQLLQLAIDCVAQVPDARPTMSHVV 257 D E+L+ S +M+ L C+ + P+ RPT + ++ Sbjct: 253 ------------DKEMLKKYGKSFRKMISL------CLQKDPEKRPTAAELL 286
>OXSR1_MOUSE (Q6P9R2) Serine/threonine-protein kinase OSR1 (EC 2.7.11.1)| (Oxidative stress-responsive 1 protein) Length = 527 Score = 46.6 bits (109), Expect = 8e-05 Identities = 46/172 (26%), Positives = 76/172 (44%), Gaps = 19/172 (11%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLV---GSSSSGPSRATG-----Y 560 EY+H H ++K+ NILL + +++D G++ + G + R T + Sbjct: 135 EYLHKNGQI--HRDVKAGNILLGEDGSVQIADFGVSAFLATGGDITRNKVRKTFVGTPCW 192 Query: 559 RAPEVTDP-RRVSQKADVFSFGVLLLELLTGKAPSQS---------ALNDEGVDLPRWVQ 410 APEV + R KAD++SFG+ +EL TG AP L ++ L VQ Sbjct: 193 MAPEVMEQVRGYDFKADIWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPSLETGVQ 252 Query: 409 SVVRSEWTSEVFDMELLRNQ-SSEEQMVQLLQLAIDCVAQVPDARPTMSHVV 257 D E+L+ S +M+ L C+ + P+ RPT + ++ Sbjct: 253 ------------DKEMLKKYGKSFRKMISL------CLQKDPEKRPTAAELL 286
>OXSR1_HUMAN (O95747) Serine/threonine-protein kinase OSR1 (EC 2.7.11.1)| (Oxidative stress-responsive 1 protein) Length = 527 Score = 46.6 bits (109), Expect = 8e-05 Identities = 46/172 (26%), Positives = 76/172 (44%), Gaps = 19/172 (11%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLV---GSSSSGPSRATG-----Y 560 EY+H H ++K+ NILL + +++D G++ + G + R T + Sbjct: 135 EYLHKNGQI--HRDVKAGNILLGEDGSVQIADFGVSAFLATGGDITRNKVRKTFVGTPCW 192 Query: 559 RAPEVTDP-RRVSQKADVFSFGVLLLELLTGKAPSQS---------ALNDEGVDLPRWVQ 410 APEV + R KAD++SFG+ +EL TG AP L ++ L VQ Sbjct: 193 MAPEVMEQVRGYDFKADIWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPSLETGVQ 252 Query: 409 SVVRSEWTSEVFDMELLRNQ-SSEEQMVQLLQLAIDCVAQVPDARPTMSHVV 257 D E+L+ S +M+ L C+ + P+ RPT + ++ Sbjct: 253 ------------DKEMLKKYGKSFRKMISL------CLQKDPEKRPTAAELL 286
>KRAF1_DROME (P11346) Raf homolog serine/threonine-protein kinase dRAF-1 (EC| 2.7.11.1) (Protein pole-hole) Length = 739 Score = 46.6 bits (109), Expect = 8e-05 Identities = 42/167 (25%), Positives = 81/167 (48%), Gaps = 8/167 (4%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVG-----SSSSGPSRATGYRAP 551 +Y+H+ + H ++KS+NI L + ++ D GLAT ++ P+ + + AP Sbjct: 537 DYLHA--KNIIHRDLKSNNIFLHEDLSVKIGDFGLATAKTRWSGEKQANQPTGSILWMAP 594 Query: 550 EVTDPRRV---SQKADVFSFGVLLLELLTGKAPSQSALNDEGVDLPRWVQSVVRSEWTSE 380 EV + + S ++DV++FG+++ ELL P N + + L + ++R Sbjct: 595 EVIRMQELNPYSFQSDVYAFGIVMYELLAECLPYGHISNKDQI-LFMVGRGLLRP----- 648 Query: 379 VFDMELLRNQSSEEQMVQLLQLAIDCVAQVPDARPTMSHVVVRIEEI 239 DM +R+ + + L +LA DC+ P RP ++ +E + Sbjct: 649 --DMSQVRSDAPQ----ALKRLAEDCIKYTPKDRPLFRPLLNMLENM 689
>KS6A_CAEEL (Q21734) Putative ribosomal protein S6 kinase alpha (EC 2.7.11.1)| Length = 784 Score = 46.6 bits (109), Expect = 8e-05 Identities = 33/90 (36%), Positives = 45/90 (50%), Gaps = 3/90 (3%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATG---YRAPEV 545 E++HS + ++K NILL +V+D GL+ S G Y APEV Sbjct: 218 EHLHSLG--IVYRDLKPENILLDADGHIKVTDFGLSKEAIDSEKKTYSFCGTVEYMAPEV 275 Query: 544 TDPRRVSQKADVFSFGVLLLELLTGKAPSQ 455 + R S AD +S GVL+ E+LTG P Q Sbjct: 276 INRRGHSMAADFWSLGVLMFEMLTGHLPFQ 305 Score = 37.7 bits (86), Expect = 0.035 Identities = 29/99 (29%), Positives = 45/99 (45%), Gaps = 7/99 (7%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLS----KAYQARVSDNGLATLVGSSSS---GPSRATGYR 557 +Y+HS +H ++ ++NIL + R+ D G A + + P + Sbjct: 561 QYLHS--QQVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAENGMLMTPCYTAQFV 618 Query: 556 APEVTDPRRVSQKADVFSFGVLLLELLTGKAPSQSALND 440 APEV + + DV+S GVLL +LTG P ND Sbjct: 619 APEVLRKQGYDRSCDVWSLGVLLHTMLTGCTPFAMGPND 657
>TESK1_RAT (Q63572) Dual specificity testis-specific protein kinase 1 (EC| 2.7.12.1) (Testicular protein kinase 1) Length = 628 Score = 46.6 bits (109), Expect = 8e-05 Identities = 45/171 (26%), Positives = 69/171 (40%), Gaps = 13/171 (7%) Frame = -1 Query: 712 YIHSTSSSTSHGNIKSSNILLSK---AYQARVSDNGLATLVGSSSSG----PSRATG--- 563 Y+H+ H ++ S N L+ + + A V D GLA + G P G Sbjct: 160 YLHA--KGVFHRDLTSKNCLVRREDGGFTAVVGDFGLAEKIPVYREGARKEPLAVVGSPY 217 Query: 562 YRAPEVTDPRRVSQKADVFSFGVLLLELLTGKAPSQSAL---NDEGVDLPRWVQSVVRSE 392 + APEV +KADVF+FG++L EL+ L D G+D+P + Sbjct: 218 WMAPEVLRGELYDEKADVFAFGIVLCELIARVPADPDYLPRTEDFGLDVPAF-------- 269 Query: 391 WTSEVFDMELLRNQSSEEQMVQLLQLAIDCVAQVPDARPTMSHVVVRIEEI 239 R + + L LAI C + P AR + + +E+I Sbjct: 270 -----------RTLVGNDCPLPFLLLAIHCCSMEPSARAPFTEITQHLEQI 309
>OXSR1_PIG (Q863I2) Serine/threonine-protein kinase OSR1 (EC 2.7.11.1)| (Oxidative stress-responsive 1 protein) Length = 529 Score = 46.6 bits (109), Expect = 8e-05 Identities = 46/172 (26%), Positives = 76/172 (44%), Gaps = 19/172 (11%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLV---GSSSSGPSRATG-----Y 560 EY+H H ++K+ NILL + +++D G++ + G + R T + Sbjct: 135 EYLHKNGQI--HRDVKAGNILLGEDGSVQIADFGVSAFLATGGDITRNKVRKTFVGTPCW 192 Query: 559 RAPEVTDP-RRVSQKADVFSFGVLLLELLTGKAPSQS---------ALNDEGVDLPRWVQ 410 APEV + R KAD++SFG+ +EL TG AP L ++ L VQ Sbjct: 193 MAPEVMEQVRGYDFKADIWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPSLETGVQ 252 Query: 409 SVVRSEWTSEVFDMELLRNQ-SSEEQMVQLLQLAIDCVAQVPDARPTMSHVV 257 D E+L+ S +M+ L C+ + P+ RPT + ++ Sbjct: 253 ------------DKEMLKKYGKSFRKMISL------CLQKDPEKRPTAAELL 286
>STK_HYDAT (P17713) Tyrosine-protein kinase STK (EC 2.7.10.2) (P57-STK)| Length = 509 Score = 46.2 bits (108), Expect = 1e-04 Identities = 28/89 (31%), Positives = 49/89 (55%), Gaps = 5/89 (5%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVG----SSSSGPSRATGYRAPEVTDPRRVSQKA 515 H ++ + NIL+ + Y +V+D GLA L+ ++ G + APE R + K+ Sbjct: 358 HRDLAARNILVGENYICKVADFGLARLIEDDEYTAHEGAKFPIKWTAPEAALYNRFTIKS 417 Query: 514 DVFSFGVLLLELLT-GKAPSQSALNDEGV 431 DV+SFG+L+ E++T G+ P N + + Sbjct: 418 DVWSFGILMAEIVTKGRIPYPGMTNAQTI 446
>BTKL_DROME (P08630) Tyrosine-protein kinase Btk29A (EC 2.7.10.2) (Dsrc28C)| Length = 786 Score = 46.2 bits (108), Expect = 1e-04 Identities = 38/123 (30%), Positives = 61/123 (49%), Gaps = 7/123 (5%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLV----GSSSSGPSRATGYRAPEVTDPRRVSQKA 515 H ++ + N L+ +V+D GLA V +SS G + PEV + R S K+ Sbjct: 645 HRDLAARNCLVGSENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEVLNYTRFSSKS 704 Query: 514 DVFSFGVLLLELLT-GKAPSQSALNDEGVD-LPRWVQSVVRSEWTSEVFD-MELLRNQSS 344 DV+++GVL+ E+ T GK P N E V+ + R + E++D M+L + Sbjct: 705 DVWAYGVLMWEIFTCGKMPYGRLKNTEVVERVQRGIILEKPKSCAKEIYDVMKLCWSHGP 764 Query: 343 EEQ 335 EE+ Sbjct: 765 EER 767
>MOS_MSVMT (P32593) Serine/threonine-protein kinase transforming protein mos| (EC 2.7.11.1) Length = 354 Score = 46.2 bits (108), Expect = 1e-04 Identities = 29/85 (34%), Positives = 46/85 (54%), Gaps = 6/85 (7%) Frame = -1 Query: 697 SSSTSHGNIKSSNILLSKAYQARVSDNG----LATLVGSSSSGPSRATGY--RAPEVTDP 536 S S H ++K +NIL+S+ ++SD G L L G +S P Y +APE+ Sbjct: 202 SQSILHLDLKPANILISEQDVCKISDFGCSQKLQVLRGRQASPPHIGGTYTHQAPEILKG 261 Query: 535 RRVSQKADVFSFGVLLLELLTGKAP 461 + KAD++SFG+ L ++ T + P Sbjct: 262 EIATPKADIYSFGITLWQMTTREVP 286
>CD2L7_HUMAN (Q9NYV4) Cell division cycle 2-related protein kinase 7 (EC| 2.7.11.22) (CDC2-related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS) Length = 1490 Score = 46.2 bits (108), Expect = 1e-04 Identities = 36/95 (37%), Positives = 48/95 (50%), Gaps = 5/95 (5%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSR----ATGYRAPE 548 EY H + H +IK SNILL+ + Q +++D GLA L S S P YR PE Sbjct: 848 EYCHK--KNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLWYRPPE 905 Query: 547 -VTDPRRVSQKADVFSFGVLLLELLTGKAPSQSAL 446 + R + DV+S G +L EL T K Q+ L Sbjct: 906 LLLGEERYTPAIDVWSCGCILGELFTKKPIFQANL 940
>PKNB_BIFLO (Q8G6P9) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 690 Score = 46.2 bits (108), Expect = 1e-04 Identities = 25/80 (31%), Positives = 45/80 (56%), Gaps = 6/80 (7%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATG------YRAPEVTDPRRVSQ 521 H +IK NI++S+ +V D G+A + S++ +++ G Y +PE V Sbjct: 144 HRDIKPGNIMISEQGVVKVMDFGIARALDDSAATMTQSQGVVGTAQYLSPEQARGETVDM 203 Query: 520 KADVFSFGVLLLELLTGKAP 461 ++D++S G +L E+LTG+ P Sbjct: 204 RSDLYSAGCVLYEMLTGRPP 223
>PHO85_YEAST (P17157) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 305 Score = 46.2 bits (108), Expect = 1e-04 Identities = 31/86 (36%), Positives = 46/86 (53%), Gaps = 4/86 (4%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVG---SSSSGPSRATGYRAPEV-TDPRRVSQKA 515 H ++K N+L++K Q ++ D GLA G ++ S YRAP+V R S Sbjct: 131 HRDLKPQNLLINKRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRTYSTSI 190 Query: 514 DVFSFGVLLLELLTGKAPSQSALNDE 437 D++S G +L E++TGK P NDE Sbjct: 191 DIWSCGCILAEMITGK-PLFPGTNDE 215
>KPC4_DROME (P83099) Putative protein kinase C, delta type homolog (EC| 2.7.11.13) Length = 643 Score = 46.2 bits (108), Expect = 1e-04 Identities = 26/83 (31%), Positives = 42/83 (50%), Gaps = 3/83 (3%) Frame = -1 Query: 676 NIKSSNILLSKAYQARVSDNGLATL---VGSSSSGPSRATGYRAPEVTDPRRVSQKADVF 506 ++K N+LL R++D G+ L + ++ Y APE+ + +Q D + Sbjct: 439 DLKLDNVLLDYEGHVRIADFGMCKLQIYLDKTADSFCGTPDYMAPEIIKGEKYNQNVDWW 498 Query: 505 SFGVLLLELLTGKAPSQSALNDE 437 SFGVLL E+L G++P DE Sbjct: 499 SFGVLLYEMLIGQSPFSGCDEDE 521
>PHO85_CANGA (Q6FKD4) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 302 Score = 46.2 bits (108), Expect = 1e-04 Identities = 31/86 (36%), Positives = 46/86 (53%), Gaps = 4/86 (4%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVG---SSSSGPSRATGYRAPEV-TDPRRVSQKA 515 H ++K N+L++K Q ++ D GLA G ++ S YRAP+V R S Sbjct: 130 HRDLKPQNLLITKRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRTYSTSI 189 Query: 514 DVFSFGVLLLELLTGKAPSQSALNDE 437 D++S G +L E++TGK P NDE Sbjct: 190 DIWSCGCILAEMITGK-PLFPGTNDE 214
>LYN_MOUSE (P25911) Tyrosine-protein kinase Lyn (EC 2.7.10.2)| Length = 511 Score = 46.2 bits (108), Expect = 1e-04 Identities = 29/100 (29%), Positives = 54/100 (54%), Gaps = 12/100 (12%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSS----SGPSRATGYRAPEVTDPRRVSQKA 515 H +++++N+L+S++ +++D GLA ++ + G + APE + + K+ Sbjct: 364 HRDLRAANVLVSESLMCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKS 423 Query: 514 DVFSFGVLLLELLT-GKAPSQSALN-------DEGVDLPR 419 DV+SFG+LL E++T GK P N +G +PR Sbjct: 424 DVWSFGILLYEIVTYGKIPYPGRTNADVMSALSQGYRMPR 463
>LYN_HUMAN (P07948) Tyrosine-protein kinase Lyn (EC 2.7.10.2)| Length = 511 Score = 46.2 bits (108), Expect = 1e-04 Identities = 29/100 (29%), Positives = 54/100 (54%), Gaps = 12/100 (12%) Frame = -1 Query: 682 HGNIKSSNILLSKAYQARVSDNGLATLVGSSS----SGPSRATGYRAPEVTDPRRVSQKA 515 H +++++N+L+S++ +++D GLA ++ + G + APE + + K+ Sbjct: 364 HRDLRAANVLVSESLMCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKS 423 Query: 514 DVFSFGVLLLELLT-GKAPSQSALN-------DEGVDLPR 419 DV+SFG+LL E++T GK P N +G +PR Sbjct: 424 DVWSFGILLYEIVTYGKIPYPGRTNADVMTALSQGYRMPR 463
>MK13_PANTR (Q9N272) Mitogen-activated protein kinase 13 (EC 2.7.11.24)| (Stress-activated protein kinase 4) Length = 365 Score = 45.8 bits (107), Expect = 1e-04 Identities = 27/84 (32%), Positives = 46/84 (54%), Gaps = 1/84 (1%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATGYRAPEV-TD 539 +YIHS + H ++K N+ +++ + ++ D GLA + +G YRAPEV Sbjct: 139 KYIHS--AGVVHRDLKPGNLAVNEDCELKILDFGLARHADAEMTGYVVTRWYRAPEVILS 196 Query: 538 PRRVSQKADVFSFGVLLLELLTGK 467 +Q D++S G ++ E+LTGK Sbjct: 197 WMHYNQTVDIWSVGCIMAEMLTGK 220
>MK13_HUMAN (O15264) Mitogen-activated protein kinase 13 (EC 2.7.11.24)| (Stress-activated protein kinase 4) (Mitogen-activated protein kinase p38 delta) (MAP kinase p38 delta) Length = 365 Score = 45.8 bits (107), Expect = 1e-04 Identities = 27/84 (32%), Positives = 46/84 (54%), Gaps = 1/84 (1%) Frame = -1 Query: 715 EYIHSTSSSTSHGNIKSSNILLSKAYQARVSDNGLATLVGSSSSGPSRATGYRAPEV-TD 539 +YIHS + H ++K N+ +++ + ++ D GLA + +G YRAPEV Sbjct: 139 KYIHS--AGVVHRDLKPGNLAVNEDCELKILDFGLARHADAEMTGYVVTRWYRAPEVILS 196 Query: 538 PRRVSQKADVFSFGVLLLELLTGK 467 +Q D++S G ++ E+LTGK Sbjct: 197 WMHYNQTVDIWSVGCIMAEMLTGK 220
>GRK5_BOVIN (P43249) G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK5) Length = 590 Score = 45.8 bits (107), Expect = 1e-04 Identities = 26/74 (35%), Positives = 38/74 (51%), Gaps = 2/74 (2%) Frame = -1 Query: 676 NIKSSNILLSKAYQARVSDNGLATLV--GSSSSGPSRATGYRAPEVTDPRRVSQKADVFS 503 ++K NILL R+SD GLA + G G GY APEV + +R D + Sbjct: 311 DLKPENILLDDYGHIRISDLGLAVKIPEGDLIRGRVGTVGYMAPEVLNNQRYGLSPDYWG 370 Query: 502 FGVLLLELLTGKAP 461 G L+ E++ G++P Sbjct: 371 LGCLIYEMIEGQSP 384 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 103,882,184 Number of Sequences: 219361 Number of extensions: 2195880 Number of successful extensions: 9029 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 8006 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 8588 length of database: 80,573,946 effective HSP length: 109 effective length of database: 56,663,597 effective search space used: 7252940416 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
