>HM13_MOUSE (Q9D8V0) Minor histocompatibility antigen H13 (EC 3.4.99.-) (Signal|
           peptide peptidase) (Presenilin-like protein 3)
          Length = 378

 Score =  103 bits (257), Expect = 4e-22
 Identities = 59/133 (44%), Positives = 82/133 (61%), Gaps = 6/133 (4%)
 Frame = -2

Query: 639 SFDAPIKLLFPT-----ADAARPFSMLGLGDIVIPGIFVALALRFDVS-RGIKNRYFNSA 478
           SF+APIKL+FP         A  F+MLGLGDIVIPGIF+AL LRFD+S +   + YF ++
Sbjct: 235 SFEAPIKLVFPQDLLEKGLEADNFAMLGLGDIVIPGIFIALLLRFDISLKKNTHTYFYTS 294

Query: 477 FLGYTAGMTATIVVMNWFQAAQPALLYIVPGVTGFVAVHSLWNGEVKPLLEFTETQPXXX 298
           F  Y  G+  TI +M+ F+ AQPALLY+VP   GF  + +L  GEV  +  + E+ P   
Sbjct: 295 FAAYIFGLGLTIFIMHIFKHAQPALLYLVPACIGFPVLVALAKGEVAEMFSYEESNPKDP 354

Query: 297 XXXXXXXEDSSQS 259
                  E+S+++
Sbjct: 355 AAETESKEESTEA 367

>HM13_HUMAN (Q8TCT9) Minor histocompatibility antigen H13 (EC 3.4.99.-) (Signal|
           peptide peptidase) (Presenilin-like protein 3) (hIMP1
           protein)
          Length = 377

 Score =  103 bits (256), Expect = 6e-22
 Identities = 56/117 (47%), Positives = 76/117 (64%), Gaps = 6/117 (5%)
 Frame = -2

Query: 639 SFDAPIKLLFPT-----ADAARPFSMLGLGDIVIPGIFVALALRFDVS-RGIKNRYFNSA 478
           SF+APIKL+FP         A  F+MLGLGD+VIPGIF+AL LRFD+S +   + YF ++
Sbjct: 235 SFEAPIKLVFPQDLLEKGLEANNFAMLGLGDVVIPGIFIALLLRFDISLKKNTHTYFYTS 294

Query: 477 FLGYTAGMTATIVVMNWFQAAQPALLYIVPGVTGFVAVHSLWNGEVKPLLEFTETQP 307
           F  Y  G+  TI +M+ F+ AQPALLY+VP   GF  + +L  GEV  +  + E+ P
Sbjct: 295 FAAYIFGLGLTIFIMHIFKHAQPALLYLVPACIGFPVLVALAKGEVTEMFSYEESNP 351

>YJ95_CAEEL (P49049) Hypothetical protein T05E11.5 in chromosome IV|
          Length = 468

 Score = 75.5 bits (184), Expect = 1e-13
 Identities = 52/127 (40%), Positives = 67/127 (52%), Gaps = 19/127 (14%)
 Frame = -2

Query: 633 DAPIKLLFPT------ADAARPFSMLGLGDIVIPGIFVALALRFDV------------SR 508
           DAPI L FP          A   SMLGLGDIVIPGIF+AL  RFD               
Sbjct: 324 DAPILLQFPQDIYRNGIMEASKHSMLGLGDIVIPGIFIALLRRFDYRVVQTTAESKAPQG 383

Query: 507 GIKNRY-FNSAFLGYTAGMTATIVVMNWFQAAQPALLYIVPGVTGFVAVHSLWNGEVKPL 331
            +K RY F    + Y AG+  T+ VM+ F+AAQPALLY+VP       + ++  GE+  L
Sbjct: 384 SLKGRYYFVVTVVAYMAGLFITMAVMHHFKAAQPALLYLVPCCLFVPLLLAVIRGELSAL 443

Query: 330 LEFTETQ 310
             + E++
Sbjct: 444 WNYDESR 450

>YKK0_YEAST (P34248) Hypothetical 67.5 kDa protein in APE1/LAP4-CWP1 intergenic|
           region
          Length = 587

 Score = 72.4 bits (176), Expect = 1e-12
 Identities = 41/125 (32%), Positives = 64/125 (51%), Gaps = 19/125 (15%)
 Frame = -2

Query: 639 SFDAPIKLLFP----TADAARPFSMLGLGDIVIPGIFVALALRFDVSR------------ 508
           + D P+KL  P    TA     FS+LGLGDI +PG+F+A+  ++D+ +            
Sbjct: 382 NLDIPVKLSLPVKFNTAQNNFNFSILGLGDIALPGMFIAMCYKYDIWKWHLDHDDTEFHF 441

Query: 507 ---GIKNRYFNSAFLGYTAGMTATIVVMNWFQAAQPALLYIVPGVTGFVAVHSLWNGEVK 337
                  +YF +A + Y A + + +V ++ F  AQPALLYIVP +     + + WN + K
Sbjct: 442 LNWSYVGKYFITAMVSYVASLVSAMVSLSIFNTAQPALLYIVPSLLISTILVACWNKDFK 501

Query: 336 PLLEF 322
               F
Sbjct: 502 QFWNF 506

>PSL1_HUMAN (Q8TCT7) Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein|
           SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4)
           (IMP4) (Presenilin-like protein 1)
          Length = 592

 Score = 70.5 bits (171), Expect = 4e-12
 Identities = 36/90 (40%), Positives = 48/90 (53%)
 Frame = -2

Query: 609 PTADAARPFSMLGLGDIVIPGIFVALALRFDVSRGIKNRYFNSAFLGYTAGMTATIVVMN 430
           P A   RPFS+LG GDI++PG+ VA   RFD+       YF +  + Y  G+  T V + 
Sbjct: 406 PLALCDRPFSLLGFGDILVPGLLVAYCHRFDIQVQSSRVYFVACTIAYGVGLLVTFVALA 465

Query: 429 WFQAAQPALLYIVPGVTGFVAVHSLWNGEV 340
             Q  QPALLY+VP         +LW  E+
Sbjct: 466 LMQRGQPALLYLVPCTLVTSCAVALWRREL 495

>PSL1_CHICK (Q5F383) Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein|
           SPP-like 2B) (Protein SPPL2b)
          Length = 596

 Score = 68.9 bits (167), Expect = 1e-11
 Identities = 38/92 (41%), Positives = 51/92 (55%), Gaps = 2/92 (2%)
 Frame = -2

Query: 609 PTADAARPFSMLGLGDIVIPGIFVALALRFDVSRGIKNRYFNSAFLGYTAGMTATIVVMN 430
           P A   RPFS+LG GDI++PG+ VA   RFD+       YF +  + Y  G+  T V + 
Sbjct: 402 PLALCDRPFSLLGFGDILVPGLLVAYCHRFDIQVQSSRVYFVACTIAYGIGLLVTFVALA 461

Query: 429 WFQAAQPALLYIVPG--VTGFVAVHSLWNGEV 340
             Q  QPALLY+VP   +T F    +LW  E+
Sbjct: 462 LMQMGQPALLYLVPCTLITSFSV--ALWRKEL 491

>PSL1_MOUSE (Q3TD49) Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein|
           SPP-like 2B) (Protein SPPL2b)
          Length = 578

 Score = 68.2 bits (165), Expect = 2e-11
 Identities = 35/90 (38%), Positives = 48/90 (53%)
 Frame = -2

Query: 609 PTADAARPFSMLGLGDIVIPGIFVALALRFDVSRGIKNRYFNSAFLGYTAGMTATIVVMN 430
           P +   RPFS+LG GDI++PG+ VA   RFD+       YF +  + Y  G+  T V + 
Sbjct: 399 PLSLCDRPFSLLGFGDILVPGLLVAYCHRFDIQVQSSRIYFVACTIAYGLGLLVTFVALV 458

Query: 429 WFQAAQPALLYIVPGVTGFVAVHSLWNGEV 340
             Q  QPALLY+VP         +LW  E+
Sbjct: 459 LMQRGQPALLYLVPCTLLTSCTVALWRREL 488

>PSL2_HUMAN (Q8TCT8) Signal peptide peptidase-like 2A (EC 3.4.23.-) (Protein|
           SPP-like 2A) (Protein SPPL2a) (Intramembrane protease 3)
           (IMP3) (Presenilin-like protein 2)
          Length = 520

 Score = 66.6 bits (161), Expect = 6e-11
 Identities = 31/67 (46%), Positives = 42/67 (62%)
 Frame = -2

Query: 588 PFSMLGLGDIVIPGIFVALALRFDVSRGIKNRYFNSAFLGYTAGMTATIVVMNWFQAAQP 409
           P S+LG GDI++PG+ +A   RFDV  G    Y+ S+ + Y  GM  T VV+   +  QP
Sbjct: 404 PVSILGFGDIIVPGLLIAYCRRFDVQTGSSYIYYVSSTVAYAIGMILTFVVLVLMKKGQP 463

Query: 408 ALLYIVP 388
           ALLY+VP
Sbjct: 464 ALLYLVP 470

>PSL1_RAT (Q5PQL3) Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein|
           SPP-like 2B) (Protein SPPL2b)
          Length = 577

 Score = 66.2 bits (160), Expect = 8e-11
 Identities = 34/90 (37%), Positives = 48/90 (53%)
 Frame = -2

Query: 609 PTADAARPFSMLGLGDIVIPGIFVALALRFDVSRGIKNRYFNSAFLGYTAGMTATIVVMN 430
           P +   RPFS+LG GDI++PG+ VA   RFD+       YF +  + Y  G+  T V + 
Sbjct: 399 PLSLCDRPFSLLGFGDILVPGLLVAYCHRFDIQVQSSRIYFVACTIAYGLGLLVTFVALV 458

Query: 429 WFQAAQPALLYIVPGVTGFVAVHSLWNGEV 340
             +  QPALLY+VP         +LW  E+
Sbjct: 459 LMRHGQPALLYLVPCTLLTSCTVALWRREM 488

>PSL2_MOUSE (Q9JJF9) Signal peptide peptidase-like 2A (EC 3.4.23.-) (SPP-like|
           2A protein) (SPPL2a protein) (Intramembrane protease 3)
           (IMP3) (Presenilin-like protein 2)
          Length = 523

 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 35/84 (41%), Positives = 50/84 (59%)
 Frame = -2

Query: 588 PFSMLGLGDIVIPGIFVALALRFDVSRGIKNRYFNSAFLGYTAGMTATIVVMNWFQAAQP 409
           P S+LG GDI++PG+ +A   RFDV  G  + Y+ S+ + Y  GM  T VV+   +  QP
Sbjct: 408 PVSVLGFGDIIVPGLLIAYCRRFDVQTG-SSIYYISSTIAYAVGMIITFVVLMVMKTGQP 466

Query: 408 ALLYIVPGVTGFVAVHSLWNGEVK 337
           ALLY+VP     V+V +    E+K
Sbjct: 467 ALLYLVPCTLITVSVVAWSRKEMK 490

>PSL4_HUMAN (Q8TCT6) Signal peptide peptidase-like 3 (EC 3.4.23.-) (SPP-like 3|
           protein) (Intramembrane protease 2) (IMP2)
           (Presenilin-like protein 4)
          Length = 385

 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 37/99 (37%), Positives = 51/99 (51%), Gaps = 19/99 (19%)
 Frame = -2

Query: 627 PIKLLFPTADAARPFSMLGLGDIVIPGIFVALALRFD-------------------VSRG 505
           P KL+FP++  +  FSMLG+GDIV+PG+ +   LR+D                     R 
Sbjct: 252 PGKLVFPSSTGSH-FSMLGIGDIVMPGLLLCFVLRYDNYKKQASGDSCGAPGPANISGRM 310

Query: 504 IKNRYFNSAFLGYTAGMTATIVVMNWFQAAQPALLYIVP 388
            K  YF+   +GY  G+    V     +AAQPALLY+VP
Sbjct: 311 QKVSYFHCTLIGYFVGLLTATVASRIHRAAQPALLYLVP 349

>PSL4_MOUSE (Q9CUS9) Signal peptide peptidase-like 3 (EC 3.4.23.-) (SPP-like 3|
           protein) (Intramembrane protease 2) (IMP2)
           (Presenilin-like protein 4)
          Length = 384

 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 37/99 (37%), Positives = 51/99 (51%), Gaps = 19/99 (19%)
 Frame = -2

Query: 627 PIKLLFPTADAARPFSMLGLGDIVIPGIFVALALRFD-------------------VSRG 505
           P KL+FP++  +  FSMLG+GDIV+PG+ +   LR+D                     R 
Sbjct: 251 PGKLVFPSSTGSH-FSMLGIGDIVMPGLLLCFVLRYDNYKKQASGDSCGAPGPANISGRM 309

Query: 504 IKNRYFNSAFLGYTAGMTATIVVMNWFQAAQPALLYIVP 388
            K  YF+   +GY  G+    V     +AAQPALLY+VP
Sbjct: 310 QKVSYFHCTLIGYFVGLLTATVASRIHRAAQPALLYLVP 348

>PSNB_ARATH (Q9SIK7) Presenilin-like protein At2g29900|
          Length = 397

 Score = 31.2 bits (69), Expect = 2.7
 Identities = 17/58 (29%), Positives = 30/58 (51%)
 Frame = -2

Query: 576 LGLGDIVIPGIFVALALRFDVSRGIKNRYFNSAFLGYTAGMTATIVVMNWFQAAQPAL 403
           LGLGD +   + V  A  +D+          + +L   AG+  T+++++ +Q A PAL
Sbjct: 314 LGLGDFIFYSVLVGRAAMYDLMT------VYACYLAIIAGLGITLMLLSVYQKALPAL 365

>ZF36_HUMAN (P16415) Zinc finger protein ZFP-36 (Fragment)|
          Length = 582

 Score = 30.8 bits (68), Expect = 3.6
 Identities = 16/52 (30%), Positives = 23/52 (44%), Gaps = 4/52 (7%)
 Frame = +1

Query: 343 FTIPQRVNSHKTSHAGNDV*QSRLCSLKPVH----HNYCCCHTRSVPQKCTI 486
           F  P  V +H+T+H G    + + C     H     ++   HT   PQKC I
Sbjct: 375 FDCPSSVRNHETTHTGEKPYECKQCGKVLSHSSSFRSHMITHTGDGPQKCKI 426

>DUOX2_HUMAN (Q9NRD8) Dual oxidase 2 precursor (EC 1.6.3.1) (EC 1.11.1.-) (NADPH|
           oxidase/peroxidase DUOX2) (NADPH thyroid oxidase 2)
           (Thyroid oxidase 2) (NADH/NADPH thyroid oxidase
           p138-tox) (p138 thyroid oxidase) (Large NOX 2) (Long NOX
           2)
          Length = 1548

 Score = 30.0 bits (66), Expect = 6.1
 Identities = 13/25 (52%), Positives = 14/25 (56%)
 Frame = +3

Query: 558 RYHQDQA*RTGVQHPQWEIEALLEH 632
           RYH   A R   QHP WE E L +H
Sbjct: 260 RYHNLWAQRLARQHPDWEDEELFQH 284

>DUOX1_HUMAN (Q9NRD9) Dual oxidase 1 precursor (EC 1.6.3.1) (EC 1.11.1.-) (NADPH|
           thyroid oxidase 1) (Thyroid oxidase 1) (Large NOX 1)
           (Long NOX 1)
          Length = 1551

 Score = 30.0 bits (66), Expect = 6.1
 Identities = 13/25 (52%), Positives = 14/25 (56%)
 Frame = +3

Query: 558 RYHQDQA*RTGVQHPQWEIEALLEH 632
           RYH   A R   QHP WE E L +H
Sbjct: 254 RYHNLWAQRLARQHPDWEDEELFQH 278

>ZN442_HUMAN (Q9H7R0) Zinc finger protein 442|
          Length = 627

 Score = 29.6 bits (65), Expect = 7.9
 Identities = 14/52 (26%), Positives = 22/52 (42%), Gaps = 4/52 (7%)
 Frame = +1

Query: 343 FTIPQRVNSHKTSHAGNDV*QSRLCSLKPVHH----NYCCCHTRSVPQKCTI 486
           F  P  + SH+ +H G    + + C     HH    ++   HT   P KC +
Sbjct: 358 FDCPSSLQSHERTHTGEKPYECKQCGKALSHHSSFRSHMIMHTGDGPHKCKV 409

>PHY2_SYNY3 (Q55434) Phytochrome-like protein cph2 (Bacteriophytochrome cph2)|
          Length = 1276

 Score = 29.6 bits (65), Expect = 7.9
 Identities = 13/23 (56%), Positives = 15/23 (65%)
 Frame = -2

Query: 417 AQPALLYIVPGVTGFVAVHSLWN 349
           A  A+LYI P +TG VA H  WN
Sbjct: 235 ADGAVLYIAPDLTGSVAQHYQWN 257


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 81,599,447
Number of Sequences: 219361
Number of extensions: 1503220
Number of successful extensions: 3685
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 3579
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3674
length of database: 80,573,946
effective HSP length: 107
effective length of database: 57,102,319
effective search space used: 5995743495
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)