>AP1G1_HUMAN (O43747) AP-1 complex subunit gamma-1 (Adapter-related protein|
            complex 1 gamma-1 subunit) (Gamma-adaptin) (Adaptor
            protein complex AP-1 gamma-1 subunit) (Golgi adaptor
            HA1/AP1 adaptin subunit gamma-1) (Clathrin assembly
            protein complex 1 gamm
          Length = 821

 Score = 77.8 bits (190), Expect = 2e-14
 Identities = 45/106 (42%), Positives = 59/106 (55%)
 Frame = -3

Query: 566  LKITFDIRKQPGKPQETTIHATFTNLTSSNYTDFIFQAAVPKFIQLRLDPASGNIVPANG 387
            LKI F   +    P  T I    +N T  + TDF+FQAAVPK  QL+L   S +IVPA  
Sbjct: 714  LKIEFTFERSNTNPSVTVITIQASNSTELDMTDFVFQAAVPKTFQLQLLSPSSSIVPAFN 773

Query: 386  KGSVTQGFSVTNNQHGQKPLAMRIRMSYKVNGEDRLEQGQVSNFPP 249
             G++TQ   V N Q  Q  L MRI+++Y   G    +  +V+NFPP
Sbjct: 774  TGTITQVIKVLNPQKQQ--LRMRIKLTYNHKGSAMQDLAEVNNFPP 817

>AP1G1_MOUSE (P22892) AP-1 complex subunit gamma-1 (Adapter-related protein|
            complex 1 gamma-1 subunit) (Gamma-adaptin) (Adaptor
            protein complex AP-1 gamma-1 subunit) (Golgi adaptor
            HA1/AP1 adaptin subunit gamma-1) (Clathrin assembly
            protein complex 1 gamm
          Length = 821

 Score = 77.4 bits (189), Expect = 3e-14
 Identities = 44/106 (41%), Positives = 59/106 (55%)
 Frame = -3

Query: 566  LKITFDIRKQPGKPQETTIHATFTNLTSSNYTDFIFQAAVPKFIQLRLDPASGNIVPANG 387
            LKI F   +    P  T I    +N T  + TDF+FQAAVPK  QL+L   S ++VPA  
Sbjct: 714  LKIEFTFERSNTNPSVTVITIQASNSTELDMTDFVFQAAVPKTFQLQLLSPSSSVVPAFN 773

Query: 386  KGSVTQGFSVTNNQHGQKPLAMRIRMSYKVNGEDRLEQGQVSNFPP 249
             G++TQ   V N Q  Q  L MRI+++Y   G    +  +V+NFPP
Sbjct: 774  TGTITQVIKVLNPQKQQ--LRMRIKLTYNHKGSAMQDLAEVNNFPP 817

>AP1G2_MOUSE (O88512) AP-1 complex subunit gamma-2 (Adapter-related protein|
           complex 1 gamma-2 subunit) (Gamma2-adaptin) (Adaptor
           protein complex AP-1 gamma-2 subunit) (G2ad)
          Length = 791

 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 36/92 (39%), Positives = 52/92 (56%)
 Frame = -3

Query: 527 PQETTIHATFTNLTSSNYTDFIFQAAVPKFIQLRLDPASGNIVPANGKGSVTQGFSVTNN 348
           P    + AT TN +  + T F+ QAAVPK  QL+L   SGN +PA G   +TQ F + N 
Sbjct: 697 PALLLVTATTTNSSKEDVTHFVCQAAVPKSFQLQLQAPSGNTIPAQGGLPITQVFRILN- 755

Query: 347 QHGQKPLAMRIRMSYKVNGEDRLEQGQVSNFP 252
              Q PL +++R++Y  +G+   E  +V N P
Sbjct: 756 -PNQAPLRLKLRLTYNHSGQPVQEIFEVDNLP 786

>AP1G2_HUMAN (O75843) AP-1 complex subunit gamma-2 (Adapter-related protein|
           complex 1 gamma-2 subunit) (Gamma2-adaptin) (Adaptor
           protein complex AP-1 gamma-2 subunit) (G2ad)
          Length = 785

 Score = 62.8 bits (151), Expect = 7e-10
 Identities = 37/105 (35%), Positives = 56/105 (53%)
 Frame = -3

Query: 566 LKITFDIRKQPGKPQETTIHATFTNLTSSNYTDFIFQAAVPKFIQLRLDPASGNIVPANG 387
           +++     + P  P    I  T TN +  + T FI QAAVPK +QL+L   SGN VPA G
Sbjct: 678 VQLNLSFIRPPENPALLLITITATNFSEGDVTHFICQAAVPKSLQLQLQAPSGNTVPARG 737

Query: 386 KGSVTQGFSVTNNQHGQKPLAMRIRMSYKVNGEDRLEQGQVSNFP 252
              +TQ F + N    + PL +++R++Y    +   E  +V+N P
Sbjct: 738 GLPITQLFRILN--PNKAPLRLKLRLTYDHFHQSVQEIFEVNNLP 780

>GGA2_YEAST (P38817) ADP-ribosylation factor-binding protein GGA2|
           (Golgi-localized, gamma ear-containing, ARF-binding
           protein 2)
          Length = 585

 Score = 52.4 bits (124), Expect = 9e-07
 Identities = 31/92 (33%), Positives = 52/92 (56%), Gaps = 1/92 (1%)
 Frame = -3

Query: 566 LKITFDIRKQPGKPQETTIHATFTNLTSSNYTDFIFQAAVPKFIQLRLDPASGNIVPANG 387
           LKI F+I ++        I + FTNL+SS  ++ +F  AVPK + L+L P S N +  N 
Sbjct: 481 LKIEFEISRESNSV--IRIKSFFTNLSSSPISNLVFLLAVPKSMSLKLQPQSSNFMIGNA 538

Query: 386 KGSVTQGFSVTN-NQHGQKPLAMRIRMSYKVN 294
           K  ++Q  ++ N   +  K L ++ +++Y VN
Sbjct: 539 KDGISQEGTIENAPANPSKALKVKWKVNYSVN 570

>GGA2_HUMAN (Q9UJY4) ADP-ribosylation factor-binding protein GGA2|
           (Golgi-localized, gamma ear-containing, ARF-binding
           protein 2) (Gamma-adaptin-related protein 2) (VHS domain
           and ear domain of gamma-adaptin) (Vear)
          Length = 613

 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 28/98 (28%), Positives = 52/98 (53%), Gaps = 3/98 (3%)
 Frame = -3

Query: 536 PGKPQETTIHATFTNLTSSNYTDFIFQAAVPKFIQLRLDPASGNIVPANG---KGSVTQG 366
           PG P+   +  T  +       D +FQ AVPK ++++L PAS + +PA       +V   
Sbjct: 509 PGHPEVQVLLLTMMSTAPQPVWDIMFQVAVPKSMRVKLQPASSSKLPAFSPLMPPAVISQ 568

Query: 365 FSVTNNQHGQKPLAMRIRMSYKVNGEDRLEQGQVSNFP 252
             + +N H ++P+ +R ++++   G+   E G+V +FP
Sbjct: 569 MLLLDNPH-KEPIRLRYKLTFNQGGQPFSEVGEVKDFP 605

>GGA2_MOUSE (Q6P5E6) ADP-ribosylation factor-binding protein GGA2|
           (Golgi-localized, gamma ear-containing, ARF-binding
           protein 2) (Gamma-adaptin-related protein 2)
          Length = 603

 Score = 49.3 bits (116), Expect = 8e-06
 Identities = 28/98 (28%), Positives = 52/98 (53%), Gaps = 3/98 (3%)
 Frame = -3

Query: 536 PGKPQETTIHATFTNLTSSNYTDFIFQAAVPKFIQLRLDPASGNIVPANG---KGSVTQG 366
           PG P    +  T  +  +    D +FQ AVPK ++++L PAS + +PA       +V   
Sbjct: 499 PGHPDVKVLLLTMMSTATQPVWDVMFQVAVPKSMRVKLQPASSSKLPAFSPLMPPAVISQ 558

Query: 365 FSVTNNQHGQKPLAMRIRMSYKVNGEDRLEQGQVSNFP 252
             + +N H ++P+ +R ++++   G+   E G+V +FP
Sbjct: 559 TLLLDNPH-KEPIRLRYKLTFNQGGQPFSEVGEVKDFP 595

>GGA3_HUMAN (Q9NZ52) ADP-ribosylation factor-binding protein GGA3|
           (Golgi-localized, gamma ear-containing, ARF-binding
           protein 3)
          Length = 723

 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 34/115 (29%), Positives = 52/115 (45%), Gaps = 10/115 (8%)
 Frame = -3

Query: 563 KITFDIRKQ--PGKPQETTIHATFTNLTSSNYTDFIFQAAVPKFIQLRLDPASGN----I 402
           +I F   K+  PG+P    +  +  N         + QAAVPK ++++L P SG      
Sbjct: 608 RILFHFAKECPPGRPDVLVVVVSMLNTAPLPVKSIVLQAAVPKSMKVKLQPPSGTELSPF 667

Query: 401 VPANGKGSVTQGFSVTNNQHGQKPLAMRIRMSYKVN---GED-RLEQGQVSNFPP 249
            P     ++TQ   + N      PL  ++R+ YK+    GE    E G+V  FPP
Sbjct: 668 SPIQPPAAITQVMLLAN------PLKEKVRLRYKLTFALGEQLSTEVGEVDQFPP 716

>GGA3_MOUSE (Q8BMI3) ADP-ribosylation factor-binding protein GGA3|
           (Golgi-localized, gamma ear-containing, ARF-binding
           protein 3)
          Length = 718

 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 33/115 (28%), Positives = 52/115 (45%), Gaps = 10/115 (8%)
 Frame = -3

Query: 563 KITFDIRKQ--PGKPQETTIHATFTNLTSSNYTDFIFQAAVPKFIQLRLDPASGN----I 402
           +I F   K+  PG+P    +  +  N         + QAAVPK ++++L P SG      
Sbjct: 603 RILFHFAKECPPGRPDVLVVVVSMLNTAPLPVKSIVLQAAVPKSMKVKLQPPSGTELSPF 662

Query: 401 VPANGKGSVTQGFSVTNNQHGQKPLAMRIRMSYKVN---GED-RLEQGQVSNFPP 249
            P     ++TQ   + N      P+  ++R+ YK+    GE    E G+V  FPP
Sbjct: 663 SPIQPPAAITQVMLLAN------PMKEKVRLRYKLTFALGEQLSTELGEVDQFPP 711

>GGA1_MOUSE (Q8R0H9) ADP-ribosylation factor-binding protein GGA1|
           (Golgi-localized, gamma ear-containing, ARF-binding
           protein 1) (Gamma-adaptin-related protein 1)
          Length = 635

 Score = 45.8 bits (107), Expect = 8e-05
 Identities = 26/100 (26%), Positives = 49/100 (49%), Gaps = 4/100 (4%)
 Frame = -3

Query: 536 PGKPQETTIHATFTNLTSSNYTDFIFQAAVPKFIQLRLDPASGNIVPANG----KGSVTQ 369
           PG+     +  +  +       + +FQ+AVPK +++RL P SG  +PA        ++TQ
Sbjct: 531 PGRSDVLVVVVSMLSTAPQPIRNIVFQSAVPKVMKVRLQPPSGTELPAFNPIVHPSAITQ 590

Query: 368 GFSVTNNQHGQKPLAMRIRMSYKVNGEDRLEQGQVSNFPP 249
              + N Q  ++ + +R ++ + +  +   E G V  FPP
Sbjct: 591 VLLLANPQ--KEKVRLRYKLIFTMGDQTYNEMGDVDQFPP 628

>GGA1_HUMAN (Q9UJY5) ADP-ribosylation factor-binding protein GGA1|
           (Golgi-localized, gamma ear-containing, ARF-binding
           protein 1) (Gamma-adaptin-related protein 1)
          Length = 639

 Score = 45.8 bits (107), Expect = 8e-05
 Identities = 25/100 (25%), Positives = 50/100 (50%), Gaps = 4/100 (4%)
 Frame = -3

Query: 536 PGKPQETTIHATFTNLTSSNYTDFIFQAAVPKFIQLRLDPASGNIVPANG----KGSVTQ 369
           PG+     +  +  +       + +FQ+AVPK ++++L P SG  +PA        ++TQ
Sbjct: 535 PGRSDVLVVVVSMLSTAPQPIRNIVFQSAVPKVMKVKLQPPSGTELPAFNPIVHPSAITQ 594

Query: 368 GFSVTNNQHGQKPLAMRIRMSYKVNGEDRLEQGQVSNFPP 249
              + N Q  ++ + +R ++++ +  +   E G V  FPP
Sbjct: 595 VLLLANPQ--KEKVRLRYKLTFTMGDQTYNEMGDVDQFPP 632

>GGA1_YEAST (Q06336) ADP-ribosylation factor-binding protein GGA1|
           (Golgi-localized, gamma ear-containing, ARF-binding
           protein 1)
          Length = 557

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 24/81 (29%), Positives = 43/81 (53%), Gaps = 1/81 (1%)
 Frame = -3

Query: 500 FTNLTSSNYTDFIFQAAVPKFIQLRLDPASGNIVPANGKGSVTQGFSVTN-NQHGQKPLA 324
           ++N++S   T+F    A PK   L L P SGN++ +N +  + Q  SV   + +  KP+ 
Sbjct: 473 YSNISSDPITNFALLVASPKGTTLSLQPQSGNMLQSNSRDGIKQIASVEGISVNLGKPIK 532

Query: 323 MRIRMSYKVNGEDRLEQGQVS 261
           ++ + +Y   G+ + E G  S
Sbjct: 533 LKWKANYCTKGDSKEESGTTS 553

>YD85_SCHPO (Q10410) Hypothetical protein C1F3.05 in chromosome I|
          Length = 510

 Score = 37.7 bits (86), Expect = 0.023
 Identities = 21/70 (30%), Positives = 40/70 (57%), Gaps = 1/70 (1%)
 Frame = -3

Query: 473 TDFIFQAAVPKFIQLRLDPASGNIVPANGKGSVTQGF-SVTNNQHGQKPLAMRIRMSYKV 297
           ++ +FQ AV K ++L+L P +G+ + A GK +      ++TN       L +R R+ + +
Sbjct: 436 SEVVFQVAVVKSLKLQLLPHTGDAIIAPGKQNAAHEIMNITNIPADASDLRIRWRVQWII 495

Query: 296 NGEDRLEQGQ 267
             + R+EQG+
Sbjct: 496 GTDHRVEQGE 505

>AP1G1_USTMA (Q99128) AP-1 complex subunit gamma-1 (Gamma(1)-adaptin) (Clathrin|
            assembly protein large gamma-1 chain) (Clathrin assembly
            protein complex 1 gamma-1 large chain) (Gamma-ADA)
          Length = 853

 Score = 35.4 bits (80), Expect = 0.11
 Identities = 29/98 (29%), Positives = 50/98 (51%)
 Frame = -3

Query: 566  LKITFDIRKQPGKPQETTIHATFTNLTSSNYTDFIFQAAVPKFIQLRLDPASGNIVPANG 387
            L IT      P +P+   I A FT+ TS+  ++  FQAAVPK  +L++   S + V  + 
Sbjct: 753  LTITLTPTTNPARPEIVHITARFTSATSA-ISNINFQAAVPKTHKLQMQAISNSTV--HP 809

Query: 386  KGSVTQGFSVTNNQHGQKPLAMRIRMSYKVNGEDRLEQ 273
              + TQ   V         + +R+R++++V+G    +Q
Sbjct: 810  DSTETQPLRVMVPPGA--AVRLRLRIAFQVDGHSVQDQ 845

>NAGZ_VIBFU (P96157) Beta-hexosaminidase (EC 3.2.1.52)|
           (N-acetyl-beta-glucosaminidase)
           (Beta-N-acetylhexosaminidase)
          Length = 329

 Score = 30.4 bits (67), Expect = 3.6
 Identities = 17/43 (39%), Positives = 24/43 (55%)
 Frame = +3

Query: 147 AEKV*QEIRISPLPRAQT*LSQQNIGYTQMTLYSRWKIADLAL 275
           A  V  ++ IS +P+AQ+ L QQ   Y ++    RWK A  AL
Sbjct: 279 AVAVLDQLPISVVPQAQSLLKQQQFTYRELKATERWKQAYQAL 321

>TINAL_MOUSE (Q99JR5) Tubulointerstitial nephritis antigen-like precursor|
           (Androgen-regulated gene 1 protein) (Adrenocortical
           zonation factor 1) (AZ-1) (Tubulointersititial nephritis
           antigen-related protein) (TARP)
          Length = 466

 Score = 29.6 bits (65), Expect = 6.2
 Identities = 13/45 (28%), Positives = 21/45 (46%), Gaps = 2/45 (4%)
 Frame = -2

Query: 369 RFQCHE*SAWA--ETTCNADPDVLQSERRGQVGTRPSQQFSTWSI 241
           R  CHE   W   +  C  DPD++++  RG  G +     + W +
Sbjct: 123 RCTCHEGGHWECDQEPCLVDPDMIKAINRGNYGWQAGNHSAFWGM 167

>Y2320_MYCBO (P63485) Hypothetical protein Mb2320|
          Length = 323

 Score = 29.6 bits (65), Expect = 6.2
 Identities = 20/50 (40%), Positives = 30/50 (60%), Gaps = 5/50 (10%)
 Frame = +3

Query: 183 LPRAQT*LSQQNIGYTQMTLYS--RWKIADLALFQPVLA--VHF-VRHPD 317
           +P  +  L   +IG   ++ YS  RW+ AD AL +PV++  VHF + HPD
Sbjct: 129 MPGMRDLLDSGDIGAAGVSNYSLARWRKADAALGRPVVSNQVHFSLAHPD 178

>Y2298_MYCTU (P63484) Hypothetical protein Rv2298/MT2355|
          Length = 323

 Score = 29.6 bits (65), Expect = 6.2
 Identities = 20/50 (40%), Positives = 30/50 (60%), Gaps = 5/50 (10%)
 Frame = +3

Query: 183 LPRAQT*LSQQNIGYTQMTLYS--RWKIADLALFQPVLA--VHF-VRHPD 317
           +P  +  L   +IG   ++ YS  RW+ AD AL +PV++  VHF + HPD
Sbjct: 129 MPGMRDLLDSGDIGAAGVSNYSLARWRKADAALGRPVVSNQVHFSLAHPD 178

>PYRC_LACLA (Q9CGM7) Dihydroorotase (EC 3.5.2.3) (DHOase)|
          Length = 423

 Score = 29.6 bits (65), Expect = 6.2
 Identities = 16/66 (24%), Positives = 31/66 (46%), Gaps = 6/66 (9%)
 Frame = -3

Query: 542 KQPGKPQETTIHATFTNLTSSNYTDFIFQA------AVPKFIQLRLDPASGNIVPANGKG 381
           ++PG+  + TIH+   +  +  +T  +  A      + PK +   L+ A    +  +  G
Sbjct: 64  REPGQTHKETIHSGAKSAAAGGFTRVVMMANTKPILSTPKVLTETLEIADKEDIKIDAVG 123

Query: 380 SVTQGF 363
           S+TQ F
Sbjct: 124 SITQDF 129

>WIPI3_CHICK (Q5ZL16) WD-repeat domain phosphoinositide-interacting protein 3|
           (WIPI-3) (WD-repeat protein 45-like) (WDR45-like
           protein)
          Length = 344

 Score = 29.3 bits (64), Expect = 8.1
 Identities = 20/61 (32%), Positives = 30/61 (49%), Gaps = 2/61 (3%)
 Frame = -3

Query: 407 NIVPAN--GKGSVTQGFSVTNNQHGQKPLAMRIRMSYKVNGEDRLEQGQVSNFPPGV*GH 234
           N++PAN  G G +  GF   N  HG    A  +   ++V   D L++ +   FP G  GH
Sbjct: 2   NLLPANPHGNGLLYAGF---NQDHGC--FACGMENGFRVYNADPLKEKEKQEFPEGGVGH 56

Query: 233 L 231
           +
Sbjct: 57  V 57


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 88,635,192
Number of Sequences: 219361
Number of extensions: 1915755
Number of successful extensions: 4162
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 4048
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4156
length of database: 80,573,946
effective HSP length: 106
effective length of database: 57,321,680
effective search space used: 4700377760
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)