ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | rbags21i06 |
|---|---|
| Clone Library Name | barley_pub |
>TMKL1_ARATH (P33543) Putative kinase-like protein TMKL1 precursor| Length = 674 Score = 89.0 bits (219), Expect = 1e-17 Identities = 53/134 (39%), Positives = 80/134 (59%), Gaps = 3/134 (2%) Frame = -3 Query: 606 GYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQS-QGQEDVIDLPRWVHSVVREEW 430 GY+APE ++ +K +SDVY+FG+L++E+L GK P +S + + +DLP V + V EE Sbjct: 541 GYKAPELHKMKKCNPRSDVYAFGILLLEILMGKKPGKSGRNGNEFVDLPSLVKAAVLEET 600 Query: 429 TAEVFDVALMK--YHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTASES 256 T EVFD+ MK +E+ LV L+LAM C + RP+M EV++ +E+ R S + Sbjct: 601 TMEVFDLEAMKGIRSPMEEGLVHALKLAMGCCAPVTTVRPSMEEVVKQLEENRPRNRS-A 659 Query: 255 RASSNENPRDSNPP 214 S E D+ P Sbjct: 660 LYSPTETRSDAETP 673
>BRL3_ARATH (Q9LJF3) Serine/threonine-protein kinase BRI1-like 3 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 3) Length = 1164 Score = 79.3 bits (194), Expect = 9e-15 Identities = 42/119 (35%), Positives = 70/119 (58%) Frame = -3 Query: 630 INTSRVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDVIDLPRWVH 451 ++T GY PE Y+S + T K DVYS+GV+++E+L+GK P+ + + +L W Sbjct: 1019 VSTLAGTPGYVPPEYYQSFRCTAKGDVYSYGVILLELLSGKKPIDPEEFGEDNNLVGWAK 1078 Query: 450 SVVREEWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQ 274 + RE+ AE+ D L+ + + EL+ L++A C P +RPTM +V+ M ++L Q Sbjct: 1079 QLYREKRGAEILDPELVTDKSGDVELLHYLKIASQCLDDRPFKRPTMIQVMTMFKELVQ 1137
>BRL1_ARATH (Q9ZWC8) Serine/threonine-protein kinase BRI1-like 1 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 1) Length = 1166 Score = 75.9 bits (185), Expect = 1e-13 Identities = 40/124 (32%), Positives = 70/124 (56%) Frame = -3 Query: 630 INTSRVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDVIDLPRWVH 451 ++T GY PE Y+S + T K DVYS+GV+++E+L+GK P+ + +L W Sbjct: 1021 VSTLAGTPGYVPPEYYQSFRCTAKGDVYSYGVILLELLSGKKPIDPGEFGEDNNLVGWAK 1080 Query: 450 SVVREEWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQF 271 + RE+ AE+ D L+ + + EL L++A C P +RPTM +++ M ++++ Sbjct: 1081 QLYREKRGAEILDPELVTDKSGDVELFHYLKIASQCLDDRPFKRPTMIQLMAMFKEMKAD 1140 Query: 270 TASE 259 T + Sbjct: 1141 TEED 1144
>BRI1_ARATH (O22476) BRASSINOSTEROID INSENSITIVE 1 precursor (EC 2.7.11.1)| (AtBRI1) (Brassinosteroid LRR receptor kinase) Length = 1196 Score = 75.5 bits (184), Expect = 1e-13 Identities = 49/131 (37%), Positives = 80/131 (61%), Gaps = 3/131 (2%) Frame = -3 Query: 630 INTSRVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDVIDLPRWV- 454 ++T GY PE Y+S + + K DVYS+GV+++E+LTGK P S D +L WV Sbjct: 1043 VSTLAGTPGYVPPEYYQSFRCSTKGDVYSYGVVLLELLTGKRPTDSPDFGD-NNLVGWVK 1101 Query: 453 -HSVVREEWTAEVFDVALMKYH-NIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDL 280 H+ +R ++VFD LMK +E EL+Q L++A+AC RRPTM +V+ M +++ Sbjct: 1102 QHAKLR---ISDVFDPELMKEDPALEIELLQHLKVAVACLDDRAWRRPTMVQVMAMFKEI 1158 Query: 279 RQFTASESRAS 247 + + +S+++ Sbjct: 1159 QAGSGIDSQST 1169
>PSKR_ARATH (Q9ZVR7) Putative phytosulfokine receptor precursor (EC 2.7.11.1)| (Phytosulfokine LRR receptor kinase) Length = 1008 Score = 73.9 bits (180), Expect = 4e-13 Identities = 38/110 (34%), Positives = 64/110 (58%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDVIDLPRWVHSVVREEW 430 +GY PE ++ T+K DVYSFGV+++E+LT K P+ + DL WV + E Sbjct: 900 LGYIPPEYGQASVATYKGDVYSFGVVLLELLTDKRPVDMCKPKGCRDLISWVVKMKHESR 959 Query: 429 TAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDL 280 +EVFD + N + E+ ++L++A C S P +RPT +++ ++D+ Sbjct: 960 ASEVFDPLIYSKEN-DKEMFRVLEIACLCLSENPKQRPTTQQLVSWLDDV 1008
>BRL2_ARATH (Q9ZPS9) Serine/threonine-protein kinase BRI1-like 2 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 2) (Protein VASCULAR HIGHWAY 1) Length = 1143 Score = 73.9 bits (180), Expect = 4e-13 Identities = 47/146 (32%), Positives = 74/146 (50%), Gaps = 14/146 (9%) Frame = -3 Query: 630 INTSRVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDVIDLPRWVH 451 ++T GY PE Y+S + T K DVYS GV+++E+L+GK P + D +L W Sbjct: 1000 VSTLAGTPGYVPPEYYQSFRCTAKGDVYSIGVVMLEILSGKRPTDKEEFGDT-NLVGWSK 1058 Query: 450 SVVREEWTAEVFDVALMKYHNIED--------------ELVQMLQLAMACTSRFPDRRPT 313 RE EV D L+K + E E+++ L++A+ C FP +RP Sbjct: 1059 MKAREGKHMEVIDEDLLKEGSSESLNEKEGFEGGVIVKEMLRYLEIALRCVDDFPSKRPN 1118 Query: 312 MAEVIRMIEDLRQFTASESRASSNEN 235 M +V+ + +LR SE+ + S+ N Sbjct: 1119 MLQVVASLRELR---GSENNSHSHSN 1141
>BAK1_ARATH (Q94F62) BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1| precursor (EC 2.7.11.1) (BRI1-associated receptor kinase 1) (Somatic embryogenesis receptor-like kinase 3) Length = 615 Score = 73.2 bits (178), Expect = 6e-13 Identities = 38/113 (33%), Positives = 69/113 (61%), Gaps = 2/113 (1%) Frame = -3 Query: 618 RVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAP--LQSQGQEDVIDLPRWVHSV 445 R +G+ APE + K + K+DV+ +GV+++E++TG+ L +D + L WV + Sbjct: 453 RGTIGHIAPEYLSTGKSSEKTDVFGYGVMLLELITGQRAFDLARLANDDDVMLLDWVKGL 512 Query: 444 VREEWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIE 286 ++E+ + DV L + ++E+ Q++Q+A+ CT P RP M+EV+RM+E Sbjct: 513 LKEKKLEALVDVDLQGNYK-DEEVEQLIQVALLCTQSSPMERPKMSEVVRMLE 564
>BRI1_LYCPE (Q8L899) Systemin receptor SR160 precursor (EC 2.7.11.1)| (Brassinosteroid LRR receptor kinase) Length = 1207 Score = 72.4 bits (176), Expect = 1e-12 Identities = 47/129 (36%), Positives = 77/129 (59%), Gaps = 1/129 (0%) Frame = -3 Query: 630 INTSRVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDVIDLPRWVH 451 ++T GY PE Y+S + + K DVYS+GV+++E+LTGK P S D +L WV Sbjct: 1048 VSTLAGTPGYVPPEYYQSFRCSTKGDVYSYGVVLLELLTGKQPTDSADFGD-NNLVGWVK 1106 Query: 450 SVVREEWTAEVFDVALMKYH-NIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQ 274 + + T +VFD L+K +IE EL+Q L++A AC +RPTM +V+ M ++++ Sbjct: 1107 LHAKGKIT-DVFDRELLKEDASIEIELLQHLKVACACLDDRHWKRPTMIQVMAMFKEIQA 1165 Query: 273 FTASESRAS 247 + +S ++ Sbjct: 1166 GSGMDSTST 1174
>BRI1_LYCES (Q8GUQ5) Brassinosteroid LRR receptor kinase precursor (EC 2.7.11.1)| (tBRI1) (Altered brassinolide sensitivity 1) (Systemin receptor SR160) Length = 1207 Score = 72.4 bits (176), Expect = 1e-12 Identities = 47/129 (36%), Positives = 77/129 (59%), Gaps = 1/129 (0%) Frame = -3 Query: 630 INTSRVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDVIDLPRWVH 451 ++T GY PE Y+S + + K DVYS+GV+++E+LTGK P S D +L WV Sbjct: 1048 VSTLAGTPGYVPPEYYQSFRCSTKGDVYSYGVVLLELLTGKQPTDSADFGD-NNLVGWVK 1106 Query: 450 SVVREEWTAEVFDVALMKYH-NIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQ 274 + + T +VFD L+K +IE EL+Q L++A AC +RPTM +V+ M ++++ Sbjct: 1107 LHAKGKIT-DVFDRELLKEDASIEIELLQHLKVACACLDDRHWKRPTMIQVMAMFKEIQA 1165 Query: 273 FTASESRAS 247 + +S ++ Sbjct: 1166 GSGMDSTST 1174
>PSKR_DAUCA (Q8LPB4) Phytosulfokine receptor precursor (EC 2.7.11.1)| (Phytosulfokine LRR receptor kinase) Length = 1021 Score = 68.9 bits (167), Expect = 1e-11 Identities = 36/110 (32%), Positives = 63/110 (57%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDVIDLPRWVHSVVREEW 430 +GY PE ++ T+K DVYSFGV+++E+LTG+ P+ DL WV + E+ Sbjct: 909 LGYIPPEYGQASVATYKGDVYSFGVVLLELLTGRRPMDVCKPRGSRDLISWVLQMKTEKR 968 Query: 429 TAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDL 280 +E+FD + + E E++ +L++A C P RPT +++ +E++ Sbjct: 969 ESEIFDPFIYDKDHAE-EMLLVLEIACRCLGENPKTRPTTQQLVSWLENI 1017
>NORK_PEA (Q8LKZ1) Nodulation receptor kinase precursor (EC 2.7.11.1)| Length = 924 Score = 67.4 bits (163), Expect = 3e-11 Identities = 33/112 (29%), Positives = 63/112 (56%) Frame = -3 Query: 618 RVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDVIDLPRWVHSVVR 439 R GY PE Y++++ + KSDV+SFGV+++E+++G+ PL + L W +R Sbjct: 759 RGTAGYLDPEYYKTQQLSEKSDVFSFGVVLLEIVSGREPLNIKRPRVEWSLVEWAKPYIR 818 Query: 438 EEWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIED 283 E+ D + ++ E L +++++A+ C + RP M +++R +ED Sbjct: 819 ASKVDEIVDPGIKGGYHAE-ALWRVVEVALQCLEPYSTYRPCMVDIVRELED 869
>RLK5_ARATH (P47735) Receptor-like protein kinase 5 precursor (EC 2.7.11.1)| Length = 999 Score = 67.4 bits (163), Expect = 3e-11 Identities = 36/110 (32%), Positives = 68/110 (61%), Gaps = 1/110 (0%) Frame = -3 Query: 606 GYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDVIDLPRWVHSVVREEWT 427 GY APE + + KSD+YSFGV+++E++TGK P S+ + D+ +WV + + + Sbjct: 863 GYIAPEYVYTLRVNEKSDIYSFGVVLLELVTGKQPTDSELGDK--DMAKWVCTALDKCGL 920 Query: 426 AEVFDVAL-MKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDL 280 V D L +K+ ++E+ +++ + + CTS P RP+M +V+ M++++ Sbjct: 921 EPVIDPKLDLKF---KEEISKVIHIGLLCTSPLPLNRPSMRKVVIMLQEV 967
>NORK_MEDTR (Q8L4H4) Nodulation receptor kinase precursor (EC 2.7.11.1) (Does not| make infections protein 2) (Symbiosis receptor-like kinase) (MtSYMRK) Length = 925 Score = 67.4 bits (163), Expect = 3e-11 Identities = 33/112 (29%), Positives = 63/112 (56%) Frame = -3 Query: 618 RVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDVIDLPRWVHSVVR 439 R GY PE Y++++ + KSDV+SFGV+++E+++G+ PL + L W +R Sbjct: 760 RGTAGYLDPEYYKTQQLSEKSDVFSFGVVLLEIVSGREPLNIKRPRIEWSLVEWAKPYIR 819 Query: 438 EEWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIED 283 E+ D + ++ E L +++++A+ C + RP M +++R +ED Sbjct: 820 ASKVDEIVDPGIKGGYHAE-ALWRVVEVALQCLEPYSTYRPCMVDIVRELED 870
>EXS_ARATH (Q9LYN8) Leucine-rich repeat receptor protein kinase EXS precursor| (EC 2.7.11.1) (Extra sporogenous cells protein) (EXCESS MICROSPOROCYTES1 protein) Length = 1192 Score = 66.2 bits (160), Expect = 8e-11 Identities = 35/110 (31%), Positives = 65/110 (59%), Gaps = 1/110 (0%) Frame = -3 Query: 606 GYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQE-DVIDLPRWVHSVVREEW 430 GY PE +S + T K DVYSFGV+++E++TGK P +E + +L W + + Sbjct: 1084 GYIPPEYGQSARATTKGDVYSFGVILLELVTGKEPTGPDFKESEGGNLVGWAIQKINQGK 1143 Query: 429 TAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDL 280 +V D L+ +++ +++LQ+AM C + P +RP M +V++ ++++ Sbjct: 1144 AVDVIDPLLVSV-ALKNSQLRLLQIAMLCLAETPAKRPNMLDVLKALKEI 1192
>RPK1_IPONI (P93194) Receptor-like protein kinase precursor (EC 2.7.11.1)| Length = 1109 Score = 66.2 bits (160), Expect = 8e-11 Identities = 41/136 (30%), Positives = 76/136 (55%), Gaps = 12/136 (8%) Frame = -3 Query: 633 PINTSRVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQS--QGQEDVIDLPR 460 P NT + +GY APE + + +SDVYS+GV+++E++T K L G+ D++ Sbjct: 975 PSNTVQGTIGYMAPENAFTTVKSRESDVYSYGVVLLELITRKKALDPSFNGETDIVG--- 1031 Query: 459 WVHSVVREEWT-----AEVFDVALMKY---HNIEDELVQMLQLAMACTSRFPDRRPTMAE 304 WV SV WT ++ D +L+ ++ +++ + L LA+ C + D+RPTM + Sbjct: 1032 WVRSV----WTQTGEIQKIVDPSLLDELIDSSVMEQVTEALSLALRCAEKEVDKRPTMRD 1087 Query: 303 VIRMIE--DLRQFTAS 262 V++ + +R +++S Sbjct: 1088 VVKQLTRWSIRSYSSS 1103
>SIRK_ARATH (O64483) Senescence-induced receptor-like serine/threonine-protein| kinase precursor (FLG22-induced receptor-like kinase 1) Length = 876 Score = 62.8 bits (151), Expect = 8e-10 Identities = 34/110 (30%), Positives = 63/110 (57%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDVIDLPRWVHSVVREEW 430 +GY PE Y +R+ KSDVYS GV+++E++TG+ + S E V + V S++ Sbjct: 738 IGYLDPEYYSTRQMNEKSDVYSLGVVLLEVITGQPAIASSKTEKV-HISDHVRSILANGD 796 Query: 429 TAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDL 280 + D L + +++ +M ++A+ACT +RPTM++V+ ++ + Sbjct: 797 IRGIVDQRLRERYDV-GSAWKMSEIALACTEHTSAQRPTMSQVVMELKQI 845
>CLV1_ARATH (Q9SYQ8) Receptor protein kinase CLAVATA1 precursor (EC 2.7.11.1)| Length = 980 Score = 62.4 bits (150), Expect = 1e-09 Identities = 40/115 (34%), Positives = 61/115 (53%), Gaps = 9/115 (7%) Frame = -3 Query: 606 GYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDVIDLPRWVHSVVREEWT 427 GY APE + K KSDVYSFGV+++E++ GK P+ G+ +D+ RWV + EE Sbjct: 859 GYIAPEYAYTLKVDEKSDVYSFGVVLLELIAGKKPVGEFGEG--VDIVRWVRNT--EEEI 914 Query: 426 AEVFDVALMKYHNIED---------ELVQMLQLAMACTSRFPDRRPTMAEVIRMI 289 + D A++ I D ++ + ++AM C RPTM EV+ M+ Sbjct: 915 TQPSDAAIVV--AIVDPRLTGYPLTSVIHVFKIAMMCVEEEAAARPTMREVVHML 967
>TMK1_ARATH (P43298) Putative receptor protein kinase TMK1 precursor (EC| 2.7.11.1) Length = 942 Score = 59.3 bits (142), Expect = 9e-09 Identities = 39/129 (30%), Positives = 61/129 (47%), Gaps = 2/129 (1%) Frame = -3 Query: 606 GYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDVIDLPRWVHS--VVREE 433 GY APE + + T K DVYSFGV++ME++TG+ L E+ I L W + +E Sbjct: 758 GYLAPEYAVTGRVTTKVDVYSFGVILMELITGRKSLDESQPEESIHLVSWFKRMYINKEA 817 Query: 432 WTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTASESR 253 + D + + + +LA C +R P +RP M + ++ L E Sbjct: 818 SFKKAIDTTIDLDEETLASVHTVAELAGHCCAREPYQRPDMGHAVNILSSL-----VELW 872 Query: 252 ASSNENPRD 226 S++NP D Sbjct: 873 KPSDQNPED 881
>APK1A_ARATH (Q06548) Protein kinase APK1A, chloroplast precursor (EC 2.7.11.1)| Length = 410 Score = 58.2 bits (139), Expect = 2e-08 Identities = 35/116 (30%), Positives = 60/116 (51%), Gaps = 1/116 (0%) Frame = -3 Query: 606 GYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDVIDLPRWVHS-VVREEW 430 GY APE + T KSDVYSFGV+++E+L+G+ + +L W +V + Sbjct: 245 GYAAPEYLATGHLTTKSDVYSFGVVLLELLSGRRAVDKNRPSGERNLVEWAKPYLVNKRK 304 Query: 429 TAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTAS 262 V D L +++E E ++ L++ C + RP M+EV+ +E ++ A+ Sbjct: 305 IFRVIDNRLQDQYSME-EACKVATLSLRCLTTEIKLRPNMSEVVSHLEHIQSLNAA 359
>NAK_ARATH (P43293) Probable serine/threonine-protein kinase NAK (EC 2.7.11.1)| Length = 389 Score = 57.4 bits (137), Expect = 4e-08 Identities = 39/131 (29%), Positives = 69/131 (52%), Gaps = 3/131 (2%) Frame = -3 Query: 606 GYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPL---QSQGQEDVIDLPRWVHSVVRE 436 GY APE + + KSDVYSFGV+++E+L+G+ + Q G+ +++D R + + Sbjct: 245 GYAAPEYLATGHLSVKSDVYSFGVVLLELLSGRRAIDKNQPVGEHNLVDWAR--PYLTNK 302 Query: 435 EWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTASES 256 V D L +++ L ++ LA+ C S RPTM E+++ +E+L + Sbjct: 303 RRLLRVMDPRLQGQYSLTRAL-KIAVLALDCISIDAKSRPTMNEIVKTMEELH---IQKE 358 Query: 255 RASSNENPRDS 223 + +NP+ S Sbjct: 359 ASKEQQNPQIS 369
>CX32_ARATH (P27450) Probable serine/threonine-protein kinase Cx32, chloroplast| precursor (EC 2.7.11.1) Length = 419 Score = 55.5 bits (132), Expect = 1e-07 Identities = 36/143 (25%), Positives = 72/143 (50%), Gaps = 5/143 (3%) Frame = -3 Query: 624 TSRVV--VGYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKA---PLQSQGQEDVIDLPR 460 T+R++ GY APE + KSDV++FGV+++E++TG + +GQE ++D Sbjct: 252 TTRIMGTYGYAAPEYMATGHLYVKSDVFAFGVVLLEIMTGLTAHNTKRPRGQESLVD--- 308 Query: 459 WVHSVVREEWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDL 280 W+ + + + +K +M ++ ++C P RP M EV+ ++E + Sbjct: 309 WLRPELSNKHRVKQIMDKGIKGQYTTKVATEMARITLSCIEPDPKNRPHMKEVVEVLEHI 368 Query: 279 RQFTASESRASSNENPRDSNPPS 211 + +R+S+ + +S+ S Sbjct: 369 QGLNVVPNRSSTKQAVANSSRSS 391
>RLCK7_ARATH (Q9LQQ8) Probable serine/threonine-protein kinase RLCKVII (EC| 2.7.11.1) Length = 423 Score = 55.1 bits (131), Expect = 2e-07 Identities = 33/128 (25%), Positives = 65/128 (50%), Gaps = 3/128 (2%) Frame = -3 Query: 606 GYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDVIDLPRWVHSVVREEWT 427 GY AP+ + + T KSD+YSFGV+++E++TG+ + + +L W + ++ Sbjct: 272 GYCAPDYAMTGQLTFKSDIYSFGVVLLELITGRKAIDNTKTRKDQNLVGWARPLFKDRRN 331 Query: 426 -AEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDL--RQFTASES 256 ++ D L + + L Q L ++ C P RP +++V+ + L ++ + Sbjct: 332 FPKMVDPLLQGQYPVRG-LYQALAISAMCVQEQPTMRPVVSDVVLALNFLASSKYDPNSP 390 Query: 255 RASSNENP 232 +SS +NP Sbjct: 391 SSSSGKNP 398
>SRK6_BRAOE (Q09092) Putative serine/threonine-protein kinase receptor precursor| (EC 2.7.11.1) (S-receptor kinase) (SRK) Length = 849 Score = 55.1 bits (131), Expect = 2e-07 Identities = 36/120 (30%), Positives = 62/120 (51%), Gaps = 8/120 (6%) Frame = -3 Query: 627 NTSRVV--VGYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDVIDLPRWV 454 NT +VV GY +PE F+ KSDV+SFGV+V+E+++GK + DL +V Sbjct: 686 NTMKVVGTYGYMSPEYAMYGIFSEKSDVFSFGVIVLEIVSGKKNRGFYNLDYENDLLSYV 745 Query: 453 HSVVREEWTAEVFDVALMKYHNIE------DELVQMLQLAMACTSRFPDRRPTMAEVIRM 292 S +E E+ D ++ + + E+++ +Q+ + C + RP M+ V+ M Sbjct: 746 WSRWKEGRALEIVDPVIVDSLSSQPSIFQPQEVLKCIQIGLLCVQELAEHRPAMSSVVWM 805
>APK1B_ARATH (P46573) Protein kinase APK1B, chloroplast precursor (EC 2.7.11.1)| Length = 412 Score = 52.8 bits (125), Expect = 9e-07 Identities = 34/119 (28%), Positives = 58/119 (48%), Gaps = 1/119 (0%) Frame = -3 Query: 606 GYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDVIDLPRWVHSVV-REEW 430 GY APE + T KSDVYS+GV+++E+L+G+ + L W ++ + Sbjct: 246 GYAAPEYLATGHLTTKSDVYSYGVVLLEVLSGRRAVDKNRPPGEQKLVEWARPLLANKRK 305 Query: 429 TAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTASESR 253 V D L +++E E ++ LA+ C + RP M EV+ +E ++ + R Sbjct: 306 LFRVIDNRLQDQYSME-EACKVATLALRCLTFEIKLRPNMNEVVSHLEHIQTLNEAGGR 363
>PBS1_ARATH (Q9FE20) Serine/threonine-protein kinase PBS1 (EC 2.7.11.1)| (AvrPphB susceptible protein 1) Length = 456 Score = 52.4 bits (124), Expect = 1e-06 Identities = 35/124 (28%), Positives = 54/124 (43%) Frame = -3 Query: 606 GYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDVIDLPRWVHSVVREEWT 427 GY APE + + T KSDVYSFGV+ +E++TG+ + S+ +L W + + Sbjct: 255 GYCAPEYAMTGQLTVKSDVYSFGVVFLELITGRKAIDSEMPHGEQNLVAWARPLFNDRRK 314 Query: 426 AEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTASESRAS 247 +K L Q L +A C RP +A+V+ + L S+ Sbjct: 315 FIKLADPRLKGRFPTRALYQALAVASMCIQEQAATRPLIADVVTALSYLANQAYDPSKDD 374 Query: 246 SNEN 235 S N Sbjct: 375 SRRN 378
>CRI4_MAIZE (O24585) Putative receptor protein kinase CRINKLY4 precursor (EC| 2.7.11.1) Length = 901 Score = 51.6 bits (122), Expect = 2e-06 Identities = 32/108 (29%), Positives = 55/108 (50%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDVIDLPRWVHSVVREEW 430 +GY PE Y T KSDVYSFGV+++E+L+G+ + Q +E ++ W +++ Sbjct: 675 LGYLDPEYYRLHYLTTKSDVYSFGVVLLEILSGRKAIDMQFEEG--NIVEWAVPLIKAGD 732 Query: 429 TAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIE 286 + D L ++E L ++ +A C RP+M +V +E Sbjct: 733 IFAILDPVLSPPSDLE-ALKKIASVACKCVRMRGKDRPSMDKVTTALE 779
>HCK_HUMAN (P08631) Tyrosine-protein kinase HCK (EC 2.7.10.2)| (p59-HCK/p60-HCK) (Hemopoietic cell kinase) Length = 525 Score = 50.1 bits (118), Expect = 6e-06 Identities = 36/120 (30%), Positives = 58/120 (48%), Gaps = 1/120 (0%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVVREE 433 + + APE FT KSDV+SFG+L+ME++T G+ P +VI + + R E Sbjct: 420 IKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRALERGYRMPRPE 479 Query: 432 WTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTASESR 253 N +EL ++ M C P+ RPT + +++D +TA+ES+ Sbjct: 480 --------------NCPEELYNIM---MRCWKNRPEERPTFEYIQSVLDDF--YTATESQ 520
>LCK_HUMAN (P06239) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell-specific protein-tyrosine kinase) Length = 508 Score = 49.3 bits (116), Expect = 1e-05 Identities = 37/120 (30%), Positives = 59/120 (49%), Gaps = 1/120 (0%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVVREE 433 + + APE FT KSDV+SFG+L+ E++T G+ P +VI + +VR + Sbjct: 403 IKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPD 462 Query: 432 WTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTASESR 253 N +EL Q+++L C P+ RPT + ++ED FTA+E + Sbjct: 463 --------------NCPEELYQLMRL---CWKERPEDRPTFDYLRSVLEDF--FTATEGQ 503
>IRAK4_MOUSE (Q8R4K2) Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1)| (IRAK-4) Length = 459 Score = 49.3 bits (116), Expect = 1e-05 Identities = 37/121 (30%), Positives = 67/121 (55%), Gaps = 4/121 (3%) Frame = -3 Query: 630 INTSRVV--VGYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPL-QSQGQEDVIDLPR 460 + TSR+V Y APE + T KSD+YSFGV+++E++TG A + +++ + ++D+ Sbjct: 343 VMTSRIVGTTAYMAPEALRG-EITPKSDIYSFGVVLLELITGLAAVDENREPQLLLDIKE 401 Query: 459 WVHSVVREEWTAEVFDVALMKYHNIEDELVQ-MLQLAMACTSRFPDRRPTMAEVIRMIED 283 + EE T E D K + + V+ M A C +RRP +A+V +++++ Sbjct: 402 EIED---EEKTIE--DYTDEKMSDADPASVEAMYSAASQCLHEKKNRRPDIAKVQQLLQE 456 Query: 282 L 280 + Sbjct: 457 M 457
>FGFR1_RAT (Q04589) Basic fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) (FGFR-1) (bFGF-R) (MFR) Length = 822 Score = 49.3 bits (116), Expect = 1e-05 Identities = 38/137 (27%), Positives = 66/137 (48%), Gaps = 1/137 (0%) Frame = -3 Query: 618 RVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVV 442 R+ V + APE R +TH+SDV+SFGVL+ E+ T G +P E++ L + H Sbjct: 661 RLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPNPGVPVEELFKLLKEGH--- 717 Query: 441 REEWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTAS 262 + K N +EL M++ C + P +RPT +++ ++ + T++ Sbjct: 718 -----------RMDKPSNCTNELYMMMR---DCWNAVPSQRPTFKQLVEDLDRIVALTSN 763 Query: 261 ESRASSNENPRDSNPPS 211 + + P D + PS Sbjct: 764 QEYLDLS-MPLDQDSPS 779
>FGFR1_XENLA (P22182) Fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) (FGFR-1) Length = 812 Score = 49.3 bits (116), Expect = 1e-05 Identities = 42/136 (30%), Positives = 64/136 (47%), Gaps = 1/136 (0%) Frame = -3 Query: 618 RVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVV 442 R+ V + APE R +TH+SDV+SFGVL+ E+ T G +P E++ L + H Sbjct: 655 RLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPMEELFKLLKEGH--- 711 Query: 441 REEWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTAS 262 + K N +EL M++ C P +RPT + ++EDL + A Sbjct: 712 -----------RMDKPTNCTNELYMMMK---DCWHAMPSQRPTFNQ---LVEDLDRILA- 753 Query: 261 ESRASSNENPRDSNPP 214 SSN+ D + P Sbjct: 754 ---LSSNQEYLDLSMP 766
>BMX_MOUSE (P97504) Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2)| (Bone marrow tyrosine kinase gene in chromosome X protein homolog) Length = 651 Score = 49.3 bits (116), Expect = 1e-05 Identities = 29/113 (25%), Positives = 54/113 (47%), Gaps = 1/113 (0%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVVREE 433 V + APE + K++ KSDV++FG+L+ E+ + GK P +V+ H + R + Sbjct: 552 VKWSAPEVFHYFKYSSKSDVWAFGILMWEVFSLGKQPYDLYDNSEVVVKVSQGHRLYRPQ 611 Query: 432 WTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQ 274 ++ + Q+ +C P++RPT +++ IE LR+ Sbjct: 612 LASDT-----------------IYQIMYSCWHELPEKRPTFQQLLSAIEPLRE 647
>FGFR2_XENLA (Q03364) Fibroblast growth factor receptor 2 precursor (EC| 2.7.10.1) (FGFR-2) Length = 813 Score = 48.9 bits (115), Expect = 1e-05 Identities = 35/124 (28%), Positives = 58/124 (46%), Gaps = 1/124 (0%) Frame = -3 Query: 627 NTSRVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVH 451 + R+ V + APE R +TH+SDV+SFGVL+ E+ T G +P E++ L + H Sbjct: 651 SNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGH 710 Query: 450 SVVREEWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQF 271 + K N +EL M++ C P RPT +++ ++ + Sbjct: 711 --------------RMDKPANCTNELYMMMR---DCWHAIPSHRPTFKQLVEDLDRILTL 753 Query: 270 TASE 259 T +E Sbjct: 754 TTNE 757
>CEK3_CHICK (P18461) Tyrosine kinase receptor CEK3 precursor (EC 2.7.10.1)| Length = 823 Score = 48.9 bits (115), Expect = 1e-05 Identities = 35/121 (28%), Positives = 58/121 (47%), Gaps = 1/121 (0%) Frame = -3 Query: 618 RVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVV 442 R+ V + APE R +TH+SDV+SFGVL+ E+ T G +P E++ L + H Sbjct: 666 RLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGH--- 722 Query: 441 REEWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTAS 262 + K N +EL M++ C P +RPT +++ ++ + T + Sbjct: 723 -----------RMDKPANCTNELYMMMR---DCWQAVPSQRPTFKQLVEDLDRILTLTTN 768 Query: 261 E 259 E Sbjct: 769 E 769
>KPRO_MAIZE (P17801) Putative receptor protein kinase ZmPK1 precursor (EC| 2.7.11.1) Length = 817 Score = 48.9 bits (115), Expect = 1e-05 Identities = 36/124 (29%), Positives = 57/124 (45%), Gaps = 14/124 (11%) Frame = -3 Query: 618 RVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDVIDLPRWVHSVVR 439 R +GY APE S T K DVYS+GV+++E+LTG + G D VHS++R Sbjct: 696 RGTLGYIAPEWVSSLPITAKVDVYSYGVVLLELLTGTRVSELVGGTDE------VHSMLR 749 Query: 438 --------------EEWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEV 301 + W D L + N + +++LA++C +RPTM Sbjct: 750 KLVRMLSAKLEGEEQSWIDGYLDSKLNRPVNYV-QARTLIKLAVSCLEEDRSKRPTMEHA 808 Query: 300 IRMI 289 ++ + Sbjct: 809 VQTL 812
>FGFR2_HUMAN (P21802) Fibroblast growth factor receptor 2 precursor (EC 2.7.10.1)| (FGFR-2) (Keratinocyte growth factor receptor 2) (CD332 antigen) Length = 821 Score = 48.9 bits (115), Expect = 1e-05 Identities = 38/137 (27%), Positives = 64/137 (46%), Gaps = 1/137 (0%) Frame = -3 Query: 618 RVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVV 442 R+ V + APE R +TH+SDV+SFGVL+ E+ T G +P E++ L + H Sbjct: 664 RLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGH--- 720 Query: 441 REEWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTAS 262 + K N +EL M++ C P +RPT +++ ++ + T + Sbjct: 721 -----------RMDKPANCTNELYMMMR---DCWHAVPSQRPTFKQLVEDLDRILTLTTN 766 Query: 261 ESRASSNENPRDSNPPS 211 E ++ P + PS Sbjct: 767 EEYLDLSQ-PLEQYSPS 782
>FGFR2_MOUSE (P21803) Fibroblast growth factor receptor 2 precursor (EC| 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor) Length = 821 Score = 48.5 bits (114), Expect = 2e-05 Identities = 35/121 (28%), Positives = 58/121 (47%), Gaps = 1/121 (0%) Frame = -3 Query: 618 RVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVV 442 R+ V + APE R +TH+SDV+SFGVL+ E+ T G +P E++ L + H Sbjct: 664 RLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGH--- 720 Query: 441 REEWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTAS 262 + K N +EL M++ C P +RPT +++ ++ + T + Sbjct: 721 -----------RMDKPTNCTNELYMMMR---DCWHAVPSQRPTFKQLVEDLDRILTLTTN 766 Query: 261 E 259 E Sbjct: 767 E 767
>FGFR1_CHICK (P21804) Basic fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) Length = 819 Score = 48.1 bits (113), Expect = 2e-05 Identities = 38/122 (31%), Positives = 58/122 (47%), Gaps = 1/122 (0%) Frame = -3 Query: 618 RVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVV 442 R+ V + APE R +TH+SDV+SFGVL+ E+ T G +P E++ L + H Sbjct: 659 RLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGH--- 715 Query: 441 REEWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTAS 262 + K N +EL M++ C P +RPT + ++EDL + A Sbjct: 716 -----------RMDKPSNCTNELYMMMR---DCWHAVPSQRPTFKQ---LVEDLDRIVAM 758 Query: 261 ES 256 S Sbjct: 759 TS 760
>FGFR1_HUMAN (P11362) Basic fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) (FGFR-1) (bFGF-R) (Fms-like tyrosine kinase 2) (c-fgr) (CD331 antigen) Length = 822 Score = 48.1 bits (113), Expect = 2e-05 Identities = 41/136 (30%), Positives = 64/136 (47%), Gaps = 1/136 (0%) Frame = -3 Query: 618 RVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVV 442 R+ V + APE R +TH+SDV+SFGVL+ E+ T G +P E++ L + H Sbjct: 661 RLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGH--- 717 Query: 441 REEWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTAS 262 + K N +EL M++ C P +RPT + ++EDL + A Sbjct: 718 -----------RMDKPSNCTNELYMMMR---DCWHAVPSQRPTFKQ---LVEDLDRIVA- 759 Query: 261 ESRASSNENPRDSNPP 214 +SN+ D + P Sbjct: 760 ---LTSNQEYLDLSMP 772
>FGFR1_MOUSE (P16092) Basic fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) (FGFR-1) (bFGF-R) (MFR) Length = 822 Score = 47.8 bits (112), Expect = 3e-05 Identities = 34/121 (28%), Positives = 59/121 (48%), Gaps = 1/121 (0%) Frame = -3 Query: 618 RVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVV 442 R+ V + APE R +TH+SDV+SFGVL+ E+ T G +P E++ L + H Sbjct: 661 RLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGH--- 717 Query: 441 REEWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTAS 262 + K N +EL M++ C P +RPT +++ ++ + T++ Sbjct: 718 -----------RMDKPSNCTNELYMMMR---DCWHAVPSQRPTFKQLVEDLDRIVALTSN 763 Query: 261 E 259 + Sbjct: 764 Q 764
>HCK_MOUSE (P08103) Tyrosine-protein kinase HCK (EC 2.7.10.2)| (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK) Length = 523 Score = 47.8 bits (112), Expect = 3e-05 Identities = 34/120 (28%), Positives = 58/120 (48%), Gaps = 1/120 (0%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVVREE 433 + + APE FT KSDV+SFG+L+ME++T G+ P +VI + + R + Sbjct: 418 IKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRALEHGYRMPRPD 477 Query: 432 WTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTASESR 253 N +EL ++ + C P+ RPT + +++D +TA+ES+ Sbjct: 478 --------------NCPEELYNIM---IRCWKNRPEERPTFEYIQSVLDDF--YTATESQ 518
>HCK_RAT (P50545) Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK)| (Hemopoietic cell kinase) Length = 502 Score = 47.8 bits (112), Expect = 3e-05 Identities = 34/120 (28%), Positives = 58/120 (48%), Gaps = 1/120 (0%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVVREE 433 + + APE FT KSDV+SFG+L+ME++T G+ P +VI + + R + Sbjct: 397 IKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRALEHGYRMPRPD 456 Query: 432 WTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTASESR 253 N +EL ++ + C P+ RPT + +++D +TA+ES+ Sbjct: 457 --------------NCPEELYSIM---IRCWKNRPEERPTFEYIQSVLDDF--YTATESQ 497
>BMX_HUMAN (P51813) Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2)| (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38) Length = 675 Score = 47.4 bits (111), Expect = 4e-05 Identities = 29/113 (25%), Positives = 52/113 (46%), Gaps = 1/113 (0%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVVREE 433 V + APE + K++ KSDV++FG+L+ E+ + GK P V+ H + R Sbjct: 576 VKWSAPEVFHYFKYSSKSDVWAFGILMWEVFSLGKQPYDLYDNSQVVLKVSQGHRLYRPH 635 Query: 432 WTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQ 274 ++ + Q+ +C P++RPT +++ IE LR+ Sbjct: 636 LASDT-----------------IYQIMYSCWHELPEKRPTFQQLLSSIEPLRE 671
>HCK_MACFA (Q95M30) Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK)| (Hemopoietic cell kinase) Length = 503 Score = 47.0 bits (110), Expect = 5e-05 Identities = 35/120 (29%), Positives = 57/120 (47%), Gaps = 1/120 (0%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVVREE 433 + + APE T KSDV+SFG+L+ME++T G+ P +VI + + R E Sbjct: 398 IKWTAPEAINFGSSTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRALERGYRMPRPE 457 Query: 432 WTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTASESR 253 N +EL ++ M C P+ RPT + +++D +TA+ES+ Sbjct: 458 --------------NCPEELYNIM---MRCWKNRPEERPTFEYIQSVLDDF--YTATESQ 498
>LCK_AOTNA (Q5PXS1) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) Length = 508 Score = 47.0 bits (110), Expect = 5e-05 Identities = 36/120 (30%), Positives = 57/120 (47%), Gaps = 1/120 (0%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVVREE 433 + + APE FT KSDV+SFG+L+ E++T G+ P +VI + +VR + Sbjct: 403 IKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPD 462 Query: 432 WTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTASESR 253 N +EL ++ M C P+ RPT + ++ED FTA+E + Sbjct: 463 --------------NCPEELYHLM---MLCWKERPEDRPTFDYLRSVLEDF--FTATEGQ 503
>FGFR4_RAT (Q498D6) Fibroblast growth factor receptor 4 precursor (EC| 2.7.10.1) (FGFR-4) Length = 800 Score = 46.6 bits (109), Expect = 6e-05 Identities = 32/115 (27%), Positives = 54/115 (46%), Gaps = 1/115 (0%) Frame = -3 Query: 627 NTSRVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVH 451 + R+ V + APE R +TH+SDV+SFG+L+ E+ T G +P E++ L R H Sbjct: 645 SNGRLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELFSLLREGH 704 Query: 450 SVVREEWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIE 286 + R N EL +++ C P +RPT +++ ++ Sbjct: 705 RMERPP--------------NCPSELYGLMR---ECWHAAPSQRPTFKQLVEALD 742
>TEC_MOUSE (P24604) Tyrosine-protein kinase Tec (EC 2.7.10.2)| Length = 630 Score = 46.2 bits (108), Expect = 8e-05 Identities = 28/106 (26%), Positives = 53/106 (50%), Gaps = 1/106 (0%) Frame = -3 Query: 594 PETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVVREEWTAEV 418 PE + +F+ KSDV+SFGVL+ E+ T G+ P + +V+ + H + R + Sbjct: 533 PEVFNYSRFSSKSDVWSFGVLMWEIFTEGRMPFEKNTNYEVVTMVTRGHRLHRPKLAT-- 590 Query: 417 FDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDL 280 KY + ++ + C P+ RP++ +++R I++L Sbjct: 591 ------KY---------LYEVMLRCWQERPEGRPSLEDLLRTIDEL 621
>M3K11_HUMAN (Q16584) Mitogen-activated protein kinase kinase kinase 11 (EC| 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline-rich kinase) Length = 847 Score = 46.2 bits (108), Expect = 8e-05 Identities = 36/127 (28%), Positives = 55/127 (43%) Frame = -3 Query: 603 YRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDVIDLPRWVHSVVREEWTA 424 + APE ++ F+ SDV+SFGVL+ E+LTG+ P + ID + V + T Sbjct: 288 WMAPEVIKASTFSKGSDVWSFGVLLWELLTGEVPYRG------IDCLAVAYGVAVNKLTL 341 Query: 423 EVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTASESRASS 244 + + QL C ++ P RRP A +++ +E L Sbjct: 342 PIPSTCPEPF----------AQLMADCWAQDPHRRPDFASILQQLEALEAQVL------- 384 Query: 243 NENPRDS 223 E PRDS Sbjct: 385 REMPRDS 391
>KPCT_MOUSE (Q02111) Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)| Length = 707 Score = 46.2 bits (108), Expect = 8e-05 Identities = 23/64 (35%), Positives = 34/64 (53%), Gaps = 8/64 (12%) Frame = -3 Query: 603 YRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDVID--------LPRWVHS 448 Y APE +K+ H D +SFGVLV EML G++P Q +E++ PRW+ Sbjct: 545 YIAPEILLGQKYNHSVDWWSFGVLVYEMLIGQSPFHGQDEEELFHSIRMDNPFYPRWLER 604 Query: 447 VVRE 436 ++ Sbjct: 605 EAKD 608
>LCK_SAISC (Q95KR7) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) Length = 508 Score = 46.2 bits (108), Expect = 8e-05 Identities = 36/120 (30%), Positives = 57/120 (47%), Gaps = 1/120 (0%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVVREE 433 + + APE FT KSDV+SFG+L+ E++T G+ P +VI + + R + Sbjct: 403 IKWTAPEAINYGTFTIKSDVWSFGILMTEIVTHGRIPYPGMTNPEVIQNLERGYRMPRPD 462 Query: 432 WTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTASESR 253 N +EL +++ M C PD RPT + ++ED FTA+E + Sbjct: 463 --------------NCPEELYKLM---MQCWRERPDDRPTFDYLRSVLEDF--FTATEGQ 503
>SRC64_DROME (P00528) Tyrosine-protein kinase Src64B (EC 2.7.10.2) (Dsrc64)| Length = 552 Score = 46.2 bits (108), Expect = 8e-05 Identities = 34/108 (31%), Positives = 49/108 (45%), Gaps = 1/108 (0%) Frame = -3 Query: 633 PINTSRVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRW 457 P SR V + APE KF+ KSDV+S+G+L+ME+ T G+ P +VI Sbjct: 436 PKQGSRFPVKWTAPEAIIYGKFSIKSDVWSYGILLMELFTYGQVPYPGMHSREVI----- 490 Query: 456 VHSVVREEWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPT 313 E F + H D + Q+L + C P++RPT Sbjct: 491 -------ENIERGFRMPKPTNHYFPDNIYQLL---LQCWDAVPEKRPT 528
>IRAK4_HUMAN (Q9NWZ3) Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1)| (IRAK-4) (NY-REN-64 antigen) Length = 460 Score = 45.8 bits (107), Expect = 1e-04 Identities = 34/121 (28%), Positives = 64/121 (52%), Gaps = 4/121 (3%) Frame = -3 Query: 630 INTSRVV--VGYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQED-VIDLPR 460 + TSR+V Y APE + T KSD+YSFGV+++E++TG + + ++D+ Sbjct: 343 VMTSRIVGTTAYMAPEALRG-EITPKSDIYSFGVVLLEIITGLPAVDEHREPQLLLDIKE 401 Query: 459 WVHSVVREEWTAEVFDVALMKYHNIEDELVQ-MLQLAMACTSRFPDRRPTMAEVIRMIED 283 + EE T E D K ++ + V+ M +A C ++RP + +V +++++ Sbjct: 402 EIED---EEKTIE--DYIDKKMNDADSTSVEAMYSVASQCLHEKKNKRPDIKKVQQLLQE 456 Query: 282 L 280 + Sbjct: 457 M 457
>LCK_MOUSE (P06240) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) Length = 508 Score = 45.8 bits (107), Expect = 1e-04 Identities = 35/120 (29%), Positives = 57/120 (47%), Gaps = 1/120 (0%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVVREE 433 + + APE FT KSDV+SFG+L+ E++T G+ P +VI + +VR + Sbjct: 403 IKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPD 462 Query: 432 WTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTASESR 253 N +EL ++ M C P+ RPT + +++D FTA+E + Sbjct: 463 --------------NCPEELYHLM---MLCWKERPEDRPTFDYLRSVLDDF--FTATEGQ 503
>MATK_HUMAN (P42679) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase) Length = 507 Score = 45.8 bits (107), Expect = 1e-04 Identities = 29/84 (34%), Positives = 45/84 (53%), Gaps = 14/84 (16%) Frame = -3 Query: 630 INTSRVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVID----- 469 +++SR+ V + APE + KFT KSDV+SFGVL+ E+ + G+AP ++V + Sbjct: 381 LDSSRLPVKWTAPEALKHGKFTSKSDVWSFGVLLWEVFSYGRAPYPKMSLKEVSEAVEKG 440 Query: 468 --------LPRWVHSVVREEWTAE 421 P VH ++ W AE Sbjct: 441 YRMEPPEGCPGPVHVLMSSCWEAE 464
>FYN_HUMAN (P06241) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) (Protooncogene Syn) (SLK) Length = 536 Score = 45.4 bits (106), Expect = 1e-04 Identities = 35/126 (27%), Positives = 59/126 (46%), Gaps = 1/126 (0%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVVREE 433 + + APE +FT KSDV+SFG+L+ E++T G+ P +V++ V R Sbjct: 429 IKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLE------QVERG- 481 Query: 432 WTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTASESR 253 + +D + + +L + C + P+ RPT + +ED FTA+E + Sbjct: 482 ----------YRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQSFLED--YFTATEPQ 529 Query: 252 ASSNEN 235 EN Sbjct: 530 YQPGEN 535
>M3LK7_DROME (P83104) Putative mitogen-activated protein kinase kinase kinase| 7-like (EC 2.7.11.25) Length = 393 Score = 45.4 bits (106), Expect = 1e-04 Identities = 27/105 (25%), Positives = 53/105 (50%) Frame = -3 Query: 603 YRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDVIDLPRWVHSVVREEWTA 424 Y APE + K+T K DVYSFG+++ E++T + P ++ P +++++ + Sbjct: 172 YMAPEAIKHLKYTAKCDVYSFGIMLWELMTRQLPYSH------LENPNSQYAIMKAISSG 225 Query: 423 EVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMI 289 E + ++ D + QL C P++RP+M E+ + + Sbjct: 226 EKLPMEAVR----SDCPEGIKQLMECCMDINPEKRPSMKEIEKFL 266
>KPCT_HUMAN (Q04759) Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)| Length = 706 Score = 45.4 bits (106), Expect = 1e-04 Identities = 22/64 (34%), Positives = 34/64 (53%), Gaps = 8/64 (12%) Frame = -3 Query: 603 YRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDVID--------LPRWVHS 448 Y APE +K+ H D +SFGVL+ EML G++P Q +E++ PRW+ Sbjct: 545 YIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMDNPFYPRWLEK 604 Query: 447 VVRE 436 ++ Sbjct: 605 EAKD 608
>KS6A1_RAT (Q63531) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 735 Score = 45.1 bits (105), Expect = 2e-04 Identities = 20/48 (41%), Positives = 30/48 (62%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDVIDL 466 V Y APE + TH +D +S+GVL+ EMLTG P Q + +++ + L Sbjct: 226 VEYMAPEVVNRQGHTHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTL 273
>FYN_MOUSE (P39688) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 533 Score = 45.1 bits (105), Expect = 2e-04 Identities = 35/126 (27%), Positives = 59/126 (46%), Gaps = 1/126 (0%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVVREE 433 + + APE +FT KSDV+SFG+L+ E++T G+ P +V++ V R Sbjct: 426 IKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLE------QVERG- 478 Query: 432 WTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTASESR 253 + +D + + +L + C + P+ RPT + +ED FTA+E + Sbjct: 479 ----------YRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQGFLED--YFTATEPQ 526 Query: 252 ASSNEN 235 EN Sbjct: 527 YQPGEN 532
>TXK_HUMAN (P42681) Tyrosine-protein kinase TXK (EC 2.7.10.2)| Length = 527 Score = 45.1 bits (105), Expect = 2e-04 Identities = 31/113 (27%), Positives = 57/113 (50%), Gaps = 1/113 (0%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVVREE 433 + + PE + K++ KSDV+SFGVL+ E+ T GK P +++ V+ E Sbjct: 430 IKWSPPEVFLFNKYSSKSDVWSFGVLMWEVFTEGKMPFENKSNLQVV------------E 477 Query: 432 WTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQ 274 +E F L + H + + ++ +C P+ RPT AE++R + ++ + Sbjct: 478 AISEGF--RLYRPHLAP---MSIYEVMYSCWHEKPEGRPTFAELLRAVTEIAE 525
>MATK_MOUSE (P41242) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK) Length = 505 Score = 45.1 bits (105), Expect = 2e-04 Identities = 27/84 (32%), Positives = 47/84 (55%), Gaps = 14/84 (16%) Frame = -3 Query: 630 INTSRVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVID----- 469 +++SR+ V + APE ++ +F+ KSDV+SFGVL+ E+ + G+AP ++V + Sbjct: 379 LDSSRLPVKWTAPEALKNGRFSSKSDVWSFGVLLWEVFSYGRAPYPKMSLKEVSEAVEKG 438 Query: 468 --------LPRWVHSVVREEWTAE 421 P VH+++ W AE Sbjct: 439 YRMEPPDGCPGSVHTLMGSCWEAE 462
>FRK_HUMAN (P42685) Tyrosine-protein kinase FRK (EC 2.7.10.2) (Nuclear| tyrosine protein kinase RAK) Length = 505 Score = 45.1 bits (105), Expect = 2e-04 Identities = 27/80 (33%), Positives = 42/80 (52%), Gaps = 14/80 (17%) Frame = -3 Query: 618 RVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDL-------- 466 ++ V + APE S KF+ KSDV+SFG+L+ E++T GK P VI + Sbjct: 394 KLPVKWTAPEAIRSNKFSIKSDVWSFGILLYEIITYGKMPYSGMTGAQVIQMLAQNYRLP 453 Query: 465 -----PRWVHSVVREEWTAE 421 P+ ++++ E W AE Sbjct: 454 QPSNCPQQFYNIMLECWNAE 473
>MATK_RAT (P41243) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase BATK) Length = 467 Score = 44.7 bits (104), Expect = 2e-04 Identities = 27/84 (32%), Positives = 47/84 (55%), Gaps = 14/84 (16%) Frame = -3 Query: 630 INTSRVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVID----- 469 +++SR+ V + APE ++ +F+ KSDV+SFGVL+ E+ + G+AP ++V + Sbjct: 341 LDSSRLPVKWTAPEALKNGRFSSKSDVWSFGVLLWEVFSYGRAPYPKMSLKEVSEAVEKG 400 Query: 468 --------LPRWVHSVVREEWTAE 421 P VH+++ W AE Sbjct: 401 YRMEPPDSCPGPVHTLMGSCWEAE 424
>YES_CHICK (P09324) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 540 Score = 44.7 bits (104), Expect = 2e-04 Identities = 33/126 (26%), Positives = 56/126 (44%), Gaps = 1/126 (0%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVVREE 433 + + APE +FT KSDV+SFG+L+ E++T G+ P +V++ + + + Sbjct: 433 IKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMVNREVLEQVERGYRMPCPQ 492 Query: 432 WTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTASESR 253 E + +L C + PD RPT + +ED FTA+E + Sbjct: 493 GCPE-----------------SLHELMKLCWKKDPDERPTFEYIQSFLED--YFTATEPQ 533 Query: 252 ASSNEN 235 +N Sbjct: 534 YQPGDN 539
>LCK_CHICK (P42683) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (Protein-tyrosine kinase C-TKL) (p56tk1) Length = 507 Score = 44.7 bits (104), Expect = 2e-04 Identities = 35/121 (28%), Positives = 55/121 (45%), Gaps = 2/121 (1%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVI-DLPRWVHSVVRE 436 + + APE FT KSDV+SFG+L+ E++T G+ P +VI +L R + Sbjct: 402 IKWTAPEAINYGTFTIKSDVWSFGILLTEIVTYGRIPYPGMTNPEVIQNLERGYRMPQPD 461 Query: 435 EWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTASES 256 E++ +L M C P+ RPT + ++ED FTA+E Sbjct: 462 NCPQELY------------------ELMMQCWKEQPEERPTFEYMKSVLEDF--FTATEG 501 Query: 255 R 253 + Sbjct: 502 Q 502
>FYN_XIPHE (P27446) Proto-oncogene tyrosine-protein kinase FYN (EC 2.7.10.2)| (P59-FYN) Length = 536 Score = 44.7 bits (104), Expect = 2e-04 Identities = 33/127 (25%), Positives = 58/127 (45%), Gaps = 2/127 (1%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVID-LPRWVHSVVRE 436 + + APE +FT KSDV+SFG+L+ E++T G+ P +V++ + R + Sbjct: 429 IKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQ 488 Query: 435 EWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTASES 256 + A + +L + C + P+ RPT + +ED FTA+E Sbjct: 489 DCPASLH------------------ELMLQCWKKDPEERPTFEYLQAFLED--YFTATEP 528 Query: 255 RASSNEN 235 + +N Sbjct: 529 QYQPGDN 535
>YRK_CHICK (Q02977) Proto-oncogene tyrosine-protein kinase Yrk (EC 2.7.10.2)| (p60-Yrk) (Yes-related kinase) Length = 535 Score = 44.7 bits (104), Expect = 2e-04 Identities = 37/126 (29%), Positives = 57/126 (45%), Gaps = 1/126 (0%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVVREE 433 + + APE KFT KSDV+SFG+L+ E++T G+ P +V++ V Sbjct: 428 IKWTAPEAALFGKFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLE-------QVERG 480 Query: 432 WTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTASESR 253 + + H D +VQ C R P+ RPT + +ED FTA+E + Sbjct: 481 YRMQCPGGCPPSLH---DVMVQ-------CWKREPEERPTFEYLQSFLED--YFTATEPQ 528 Query: 252 ASSNEN 235 +N Sbjct: 529 YQPGDN 534
>YES_HUMAN (P07947) Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2)| (p61-Yes) (c-Yes) Length = 542 Score = 44.3 bits (103), Expect = 3e-04 Identities = 34/126 (26%), Positives = 55/126 (43%), Gaps = 1/126 (0%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVVREE 433 + + APE +FT KSDV+SFG+L E++T G+ P +V++ + + + Sbjct: 435 IKWTAPEAALYGRFTIKSDVWSFGILQTELVTKGRVPYPGMVNREVLEQVERGYRMPCPQ 494 Query: 432 WTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTASESR 253 E + +L C + PD RPT + +ED FTA+E + Sbjct: 495 GCPE-----------------SLHELMNLCWKKDPDERPTFEYIQSFLED--YFTATEPQ 535 Query: 252 ASSNEN 235 EN Sbjct: 536 YQPGEN 541
>FGFR4_MOUSE (Q03142) Fibroblast growth factor receptor 4 precursor (EC 2.7.10.1)| (FGFR-4) (Protein-tyrosine kinase receptor MPK-11) Length = 799 Score = 44.3 bits (103), Expect = 3e-04 Identities = 41/151 (27%), Positives = 65/151 (43%), Gaps = 16/151 (10%) Frame = -3 Query: 627 NTSRVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVH 451 + R+ V + APE R +TH+SDV+SF +L+ E+ T G +P E++ L R H Sbjct: 644 SNGRLPVKWMAPEALFDRVYTHQSDVWSFEILLWEIFTLGGSPYPGIPVEELFSLLREGH 703 Query: 450 SVVREEWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIE----- 286 + R N EL +++ C P +RPT +++ ++ Sbjct: 704 RMERPP--------------NCPSELYGLMR---ECWHAAPSQRPTFKQLVEALDKVLLA 746 Query: 285 ------DLR----QFTASESRASSNENPRDS 223 DLR F+ S ASS + DS Sbjct: 747 VSEEYLDLRLTFGPFSPSNGDASSTCSSSDS 777
>YES_MOUSE (Q04736) Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2)| (p61-Yes) (c-Yes) Length = 540 Score = 44.3 bits (103), Expect = 3e-04 Identities = 34/126 (26%), Positives = 55/126 (43%), Gaps = 1/126 (0%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVVREE 433 + + APE +FT KSDV+SFG+L E++T G+ P +V++ + + + Sbjct: 433 IKWTAPEAALYGRFTIKSDVWSFGILQTELVTKGRVPYPGMVNREVLEQVERGYRMPCPQ 492 Query: 432 WTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTASESR 253 E + +L C + PD RPT + +ED FTA+E + Sbjct: 493 GCPE-----------------SLHELMNLCWKKDPDERPTFEYIQSFLED--YFTATEPQ 533 Query: 252 ASSNEN 235 EN Sbjct: 534 YQPGEN 539
>CEK2_CHICK (P18460) Tyrosine kinase receptor CEK2 precursor (EC 2.7.10.1)| Length = 806 Score = 44.3 bits (103), Expect = 3e-04 Identities = 32/121 (26%), Positives = 58/121 (47%), Gaps = 1/121 (0%) Frame = -3 Query: 618 RVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVV 442 R+ V + APE R +TH+SDV+SFGVL+ E+ T G +P E++ L + H Sbjct: 649 RLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGH--- 705 Query: 441 REEWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTAS 262 + K N +L +++ C P +RPT +++ ++ + T++ Sbjct: 706 -----------RMDKPANCTHDLYMIMR---ECWHAVPSQRPTFKQLVEDLDRVLTMTST 751 Query: 261 E 259 + Sbjct: 752 D 752
>FYN_XENLA (P13406) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 536 Score = 44.3 bits (103), Expect = 3e-04 Identities = 34/126 (26%), Positives = 59/126 (46%), Gaps = 1/126 (0%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVVREE 433 + + APE +FT KSDV+SFG+L+ E++T G+ P +V++ V R Sbjct: 429 IKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLE------QVERG- 481 Query: 432 WTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTASESR 253 + +D + + +L + C + P+ RPT + +ED FTA+E + Sbjct: 482 ----------YRMPCPQDCPISLHELMLNCWKKDPEERPTFEYLQGFLED--YFTATEPQ 529 Query: 252 ASSNEN 235 +N Sbjct: 530 YQPGDN 535
>LYN_RAT (Q07014) Tyrosine-protein kinase Lyn (EC 2.7.10.2)| Length = 511 Score = 44.3 bits (103), Expect = 3e-04 Identities = 34/120 (28%), Positives = 57/120 (47%), Gaps = 1/120 (0%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVVREE 433 + + APE FT KSDV+SFG+L+ E++T GK P + DV+ Sbjct: 406 IKWTAPEAINFGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNADVM------------- 452 Query: 432 WTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTASESR 253 TA + + N DEL ++++ C + RPT + +++D +TA+E + Sbjct: 453 -TALSQGYRMPRMENCPDELYDIMKM---CWKESAEERPTFDYLQSVLDDF--YTATEGQ 506
>LYN_HUMAN (P07948) Tyrosine-protein kinase Lyn (EC 2.7.10.2)| Length = 511 Score = 43.9 bits (102), Expect = 4e-04 Identities = 34/120 (28%), Positives = 57/120 (47%), Gaps = 1/120 (0%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVVREE 433 + + APE FT KSDV+SFG+L+ E++T GK P + DV+ Sbjct: 406 IKWTAPEAINFGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNADVM------------- 452 Query: 432 WTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTASESR 253 TA + + N DEL ++++ C + RPT + +++D +TA+E + Sbjct: 453 -TALSQGYRMPRVENCPDELYDIMKM---CWKEKAEERPTFDYLQSVLDDF--YTATEGQ 506
>RET_HUMAN (P07949) Proto-oncogene tyrosine-protein kinase receptor ret| precursor (EC 2.7.10.1) (C-ret) Length = 1114 Score = 43.9 bits (102), Expect = 4e-04 Identities = 31/114 (27%), Positives = 56/114 (49%), Gaps = 1/114 (0%) Frame = -3 Query: 618 RVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVV 442 R+ V + A E+ +T +SDV+SFGVL+ E++T G P E + +L + H + Sbjct: 912 RIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRME 971 Query: 441 REEWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDL 280 R + +E +M +L + C + PD+RP A++ + +E + Sbjct: 972 RPDNCSE-----------------EMYRLMLQCWKQEPDKRPVFADISKDLEKM 1008
>INSRR_MOUSE (Q9WTL4) Insulin receptor-related protein precursor (EC 2.7.10.1)| (IRR) (IR-related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain] Length = 1300 Score = 43.9 bits (102), Expect = 4e-04 Identities = 31/110 (28%), Positives = 52/110 (47%), Gaps = 1/110 (0%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVVREE 433 V + APE+ + FT SDV+SFGV++ E++T + P Q E V+ Sbjct: 1156 VRWMAPESLKDGIFTTHSDVWSFGVVLWEIVTLAEQPYQGLSNEQVLKF----------- 1204 Query: 432 WTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIED 283 V D +++ +E+ +Q+ +L C P RPT ++ I+D Sbjct: 1205 ----VMDGGVLE--ELENCPIQLQELMRLCWQHSPRLRPTFVHILDRIQD 1248
>RET_MOUSE (P35546) Proto-oncogene tyrosine-protein kinase receptor ret| precursor (EC 2.7.10.1) (C-ret) Length = 1115 Score = 43.9 bits (102), Expect = 4e-04 Identities = 31/114 (27%), Positives = 56/114 (49%), Gaps = 1/114 (0%) Frame = -3 Query: 618 RVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVV 442 R+ V + A E+ +T +SDV+SFGVL+ E++T G P E + +L + H + Sbjct: 913 RIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRME 972 Query: 441 REEWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDL 280 R + +E +M +L + C + PD+RP A++ + +E + Sbjct: 973 RPDNCSE-----------------EMYRLMLQCWKQEPDKRPVFADISKDLEKM 1009
>M3K7_MOUSE (Q62073) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1) Length = 579 Score = 43.9 bits (102), Expect = 4e-04 Identities = 25/116 (21%), Positives = 52/116 (44%), Gaps = 5/116 (4%) Frame = -3 Query: 603 YRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDVIDLPRWVHSVVREEWTA 424 + APE +E ++ K DV+S+G+++ E++T + P G Sbjct: 195 WMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPFDEIG--------------------G 234 Query: 423 EVFDVALMKYHNIEDELVQML-----QLAMACTSRFPDRRPTMAEVIRMIEDLRQF 271 F + ++ L++ L L C S+ P +RP+M E+++++ L ++ Sbjct: 235 PAFRIMWAVHNGTRPPLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHLMRY 290
>EPHA7_CHICK (O42422) Ephrin type-A receptor 7 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor CEPHA7) (Tyrosine-protein kinase receptor CEK11) Length = 993 Score = 43.9 bits (102), Expect = 4e-04 Identities = 24/80 (30%), Positives = 42/80 (52%), Gaps = 14/80 (17%) Frame = -3 Query: 618 RVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVI---------- 472 ++ V + APE + RKFT SDV+S+G+++ E+++ G+ P +DVI Sbjct: 792 KIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLP 851 Query: 471 ---DLPRWVHSVVREEWTAE 421 D P +H ++ + W E Sbjct: 852 APMDCPAGLHQLMLDCWQKE 871
>FYN_CHICK (Q05876) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 533 Score = 43.9 bits (102), Expect = 4e-04 Identities = 34/126 (26%), Positives = 59/126 (46%), Gaps = 1/126 (0%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVVREE 433 + + APE +FT KSDV+SFG+L+ E++T G+ P +V++ V R Sbjct: 426 IKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLE------QVERG- 478 Query: 432 WTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTASESR 253 + +D + + +L + C + P+ RPT + +ED FTA+E + Sbjct: 479 ----------YRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQGFLED--YFTATEPQ 526 Query: 252 ASSNEN 235 +N Sbjct: 527 YQPGDN 532
>KS6A2_MOUSE (Q9WUT3) Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1)| (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (Protein-tyrosine kinase Mpk-9) (MAP kinase-activated protein kinase 1c) (M Length = 733 Score = 43.9 bits (102), Expect = 4e-04 Identities = 20/48 (41%), Positives = 29/48 (60%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDVIDL 466 + Y APE R T +D +SFGVL+ EMLTG P Q + +++ + L Sbjct: 223 IEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMAL 270
>KS6A2_HUMAN (Q15349) Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1)| (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (MAP kinase-activated protein kinase 1c) (MAPKAPK1C) Length = 733 Score = 43.9 bits (102), Expect = 4e-04 Identities = 20/48 (41%), Positives = 29/48 (60%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDVIDL 466 + Y APE R T +D +SFGVL+ EMLTG P Q + +++ + L Sbjct: 223 IEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMAL 270
>M3K7_HUMAN (O43318) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1) Length = 606 Score = 43.9 bits (102), Expect = 4e-04 Identities = 25/116 (21%), Positives = 52/116 (44%), Gaps = 5/116 (4%) Frame = -3 Query: 603 YRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDVIDLPRWVHSVVREEWTA 424 + APE +E ++ K DV+S+G+++ E++T + P G Sbjct: 195 WMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPFDEIG--------------------G 234 Query: 423 EVFDVALMKYHNIEDELVQML-----QLAMACTSRFPDRRPTMAEVIRMIEDLRQF 271 F + ++ L++ L L C S+ P +RP+M E+++++ L ++ Sbjct: 235 PAFRIMWAVHNGTRPPLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHLMRY 290
>EPHA7_RAT (P54759) Ephrin type-A receptor 7 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) Length = 998 Score = 43.9 bits (102), Expect = 4e-04 Identities = 24/80 (30%), Positives = 42/80 (52%), Gaps = 14/80 (17%) Frame = -3 Query: 618 RVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVI---------- 472 ++ V + APE + RKFT SDV+S+G+++ E+++ G+ P +DVI Sbjct: 797 KIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLP 856 Query: 471 ---DLPRWVHSVVREEWTAE 421 D P +H ++ + W E Sbjct: 857 APMDCPAGLHQLMLDCWQKE 876
>EPHA7_HUMAN (Q15375) Ephrin type-A receptor 7 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Receptor protein-tyrosine kinase HEK11) Length = 998 Score = 43.9 bits (102), Expect = 4e-04 Identities = 24/80 (30%), Positives = 42/80 (52%), Gaps = 14/80 (17%) Frame = -3 Query: 618 RVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVI---------- 472 ++ V + APE + RKFT SDV+S+G+++ E+++ G+ P +DVI Sbjct: 797 KIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLP 856 Query: 471 ---DLPRWVHSVVREEWTAE 421 D P +H ++ + W E Sbjct: 857 APMDCPAGLHQLMLDCWQKE 876
>FGFR4_HUMAN (P22455) Fibroblast growth factor receptor 4 precursor (EC| 2.7.10.1) (FGFR-4) (CD334 antigen) Length = 802 Score = 43.9 bits (102), Expect = 4e-04 Identities = 30/115 (26%), Positives = 51/115 (44%), Gaps = 1/115 (0%) Frame = -3 Query: 627 NTSRVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVH 451 + R+ V + APE R +TH+SDV+SFG+L+ E+ T G +P E++ L R H Sbjct: 647 SNGRLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELFSLLREGH 706 Query: 450 SVVREEWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIE 286 + R ++ L C P +RPT +++ ++ Sbjct: 707 RMDRPPHCPP-----------------ELYGLMRECWHAAPSQRPTFKQLVEALD 744
>KS6A1_HUMAN (Q15418) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 735 Score = 43.5 bits (101), Expect = 5e-04 Identities = 19/48 (39%), Positives = 30/48 (62%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDVIDL 466 V Y APE + +H +D +S+GVL+ EMLTG P Q + +++ + L Sbjct: 226 VEYMAPEVVNRQGHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTL 273
>KS6AA_CHICK (P18652) Ribosomal protein S6 kinase 2 alpha (EC 2.7.11.1)| (Ribosomal protein S6 kinase II alpha) (S6KII-alpha) (P90-RSK) (MAP kinase-activated protein kinase 1) (MAPK-activated protein kinase 1) (MAPKAP kinase 1) (MAPKAPK-1) Length = 752 Score = 43.5 bits (101), Expect = 5e-04 Identities = 19/48 (39%), Positives = 30/48 (62%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDVIDL 466 V Y APE + +H +D +S+GVL+ EMLTG P Q + +++ + L Sbjct: 244 VEYMAPEVVNRQGHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTL 291
>PK1_STRTO (Q9KIG4) Serine/threonine-protein kinase PK-1 (EC 2.7.11.1)| (stoPK-1) Length = 641 Score = 43.5 bits (101), Expect = 5e-04 Identities = 43/143 (30%), Positives = 63/143 (44%), Gaps = 3/143 (2%) Frame = -3 Query: 627 NTSRVVVG---YRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDVIDLPRW 457 NT+ V+G Y APE E + DVY+ G+L+ EMLTG+ P G I L + Sbjct: 171 NTTGTVLGTVSYLAPEQIEHGTADPRVDVYACGILLYEMLTGEKP--HDGDSPAIVLYKH 228 Query: 456 VHSVVREEWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLR 277 +H V A V M Y ++ +L + T+R P+ RP A + Sbjct: 229 LHDDVPPPSAA----VPGMAY--------ELDELVASATARGPEVRPHDAVALLA----- 271 Query: 276 QFTASESRASSNENPRDSNPPSA 208 A ++RA + D+ PP A Sbjct: 272 --RARDARARLGDEQLDAVPPQA 292
>ERBB2_CANFA (O18735) Receptor tyrosine-protein kinase erbB-2 precursor (EC| 2.7.10.1) (p185erbB2) (C-erbB-2) Length = 1259 Score = 43.5 bits (101), Expect = 5e-04 Identities = 36/134 (26%), Positives = 62/134 (46%), Gaps = 2/134 (1%) Frame = -3 Query: 618 RVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVV 442 +V + + A E+ R+FTH+SDV+S+GV V E++T G P ++ DL + Sbjct: 882 KVPIKWMALESIPPRRFTHQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLP 941 Query: 441 REE-WTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTA 265 + T +V+ + +V+ + C RF R +AE RM D ++F Sbjct: 942 QPPICTIDVYMI-----------MVKCWMIDSECRPRF---RELVAEFSRMARDPQRFVV 987 Query: 264 SESRASSNENPRDS 223 ++ +P DS Sbjct: 988 IQNEDLGPASPLDS 1001
>TEC_HUMAN (P42680) Tyrosine-protein kinase Tec (EC 2.7.10.2)| Length = 631 Score = 43.5 bits (101), Expect = 5e-04 Identities = 25/106 (23%), Positives = 51/106 (48%), Gaps = 1/106 (0%) Frame = -3 Query: 594 PETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVVREEWTAEV 418 PE + +F+ KSDV+SFGVL+ E+ T G+ P + +V+ + H + + + + Sbjct: 534 PEVFNYSRFSSKSDVWSFGVLMWEVFTEGRMPFEKYTNYEVVTMVTRGHRLYQPKLASN- 592 Query: 417 FDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDL 280 + ++ + C P+ RP+ +++R I++L Sbjct: 593 ----------------YVYEVMLRCWQEKPEGRPSFEDLLRTIDEL 622
>FGFR3_HUMAN (P22607) Fibroblast growth factor receptor 3 precursor (EC| 2.7.10.1) (FGFR-3) (CD333 antigen) Length = 806 Score = 43.5 bits (101), Expect = 5e-04 Identities = 32/121 (26%), Positives = 58/121 (47%), Gaps = 1/121 (0%) Frame = -3 Query: 618 RVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVV 442 R+ V + APE R +TH+SDV+SFGVL+ E+ T G +P E++ L + H Sbjct: 655 RLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGH--- 711 Query: 441 REEWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTAS 262 + K N +L +++ C P +RPT +++ ++ + T++ Sbjct: 712 -----------RMDKPANCTHDLYMIMR---ECWHAAPSQRPTFKQLVEDLDRVLTVTST 757 Query: 261 E 259 + Sbjct: 758 D 758
>YES_XIPHE (P27447) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 543 Score = 43.5 bits (101), Expect = 5e-04 Identities = 35/139 (25%), Positives = 56/139 (40%), Gaps = 14/139 (10%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVID------------ 469 + + APE +FT KSDV+SFG+L+ E++T G+ P +V++ Sbjct: 436 IKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMVNREVLEQVDRGYRMPCPQ 495 Query: 468 -LPRWVHSVVREEWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRM 292 P +H ++R+ W E PD RPT + Sbjct: 496 GCPESLHEMMRQCWKKE------------------------------PDERPTFEYIQSF 525 Query: 291 IEDLRQFTASESRASSNEN 235 +ED FTA+E + +N Sbjct: 526 LED--YFTATEPQYQPGDN 542
>ROS_HUMAN (P08922) Proto-oncogene tyrosine-protein kinase ROS precursor (EC| 2.7.10.1) (c-ros-1) Length = 2347 Score = 43.5 bits (101), Expect = 5e-04 Identities = 35/114 (30%), Positives = 54/114 (47%), Gaps = 1/114 (0%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVVREE 433 V + APE+ FT +SDV+SFG+L+ E+LT G P + DV++ +V + R Sbjct: 2125 VRWMAPESLMDGIFTTQSDVWSFGILIWEILTLGHQPYPAHSNLDVLN---YVQTGGR-- 2179 Query: 432 WTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQF 271 L N D+L L C ++ PD+RPT + ++ R F Sbjct: 2180 ---------LEPPRNCPDDL---WNLMTQCWAQEPDQRPTFHRIQNQLQLFRNF 2221
>YES_CANFA (Q28923) Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2)| (p61-Yes) (c-Yes) Length = 538 Score = 43.5 bits (101), Expect = 5e-04 Identities = 34/126 (26%), Positives = 54/126 (42%), Gaps = 1/126 (0%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVVREE 433 + + APE +FT KSDV+SFG+L E+ T G+ P +V++ + + + Sbjct: 431 IKWTAPEAALYGRFTIKSDVWSFGILQTELTTKGRVPYPGMVNREVLEQVERGYRMPCPQ 490 Query: 432 WTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTASESR 253 E + +L C + PD RPT + +ED FTA+E + Sbjct: 491 GCPE-----------------SLHELMNLCWKKDPDERPTFEYIQSFLED--YFTAAEPQ 531 Query: 252 ASSNEN 235 EN Sbjct: 532 YQPGEN 537
>KS6AA_XENLA (P10665) Ribosomal protein S6 kinase 2 alpha (EC 2.7.11.1)| (Ribosomal protein S6 kinase II alpha) (S6KII-alpha) (P90-RSK) (MAP kinase-activated protein kinase 1) (MAPK-activated protein kinase 1) (MAPKAP kinase 1) (MAPKAPK-1) Length = 733 Score = 43.5 bits (101), Expect = 5e-04 Identities = 19/48 (39%), Positives = 30/48 (62%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDVIDL 466 V Y APE + +H +D +S+GVL+ EMLTG P Q + +++ + L Sbjct: 226 VEYMAPEVVNRQGHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTL 273
>KS6A3_MOUSE (P18654) Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1)| (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (MAP kinase-activated protein kinase 1b) (MAPKAPK1B) Length = 740 Score = 43.5 bits (101), Expect = 5e-04 Identities = 20/48 (41%), Positives = 29/48 (60%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDVIDL 466 V Y APE R T +D +SFGVL+ EMLTG P Q + +++ + + Sbjct: 232 VEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTM 279 Score = 30.4 bits (67), Expect = 4.6 Identities = 15/40 (37%), Positives = 23/40 (57%) Frame = -3 Query: 597 APETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQED 478 APE + + + D++S GVL+ MLTG P + G +D Sbjct: 586 APEVLKRQGYDAACDIWSLGVLLYTMLTGYTPF-ANGPDD 624
>KS6A3_HUMAN (P51812) Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1)| (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protei Length = 740 Score = 43.5 bits (101), Expect = 5e-04 Identities = 20/48 (41%), Positives = 29/48 (60%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDVIDL 466 V Y APE R T +D +SFGVL+ EMLTG P Q + +++ + + Sbjct: 232 VEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTM 279 Score = 30.4 bits (67), Expect = 4.6 Identities = 15/40 (37%), Positives = 23/40 (57%) Frame = -3 Query: 597 APETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQED 478 APE + + + D++S GVL+ MLTG P + G +D Sbjct: 586 APEVLKRQGYDAACDIWSLGVLLYTMLTGYTPF-ANGPDD 624
>CSK_CHICK (P41239) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| Length = 450 Score = 43.5 bits (101), Expect = 5e-04 Identities = 28/102 (27%), Positives = 52/102 (50%), Gaps = 14/102 (13%) Frame = -3 Query: 627 NTSRVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVI------- 472 +T ++ V + APE +KF+ KSDV+SFG+L+ E+ + G+ P +DV+ Sbjct: 344 DTGKLPVKWTAPEALREKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVEKGY 403 Query: 471 ------DLPRWVHSVVREEWTAEVFDVALMKYHNIEDELVQM 364 P V+ V+++ WT + +H + ++LV + Sbjct: 404 KMDPPDGCPAIVYEVMKKCWTLD--PGHRPSFHQLREQLVHI 443
>LYN_MOUSE (P25911) Tyrosine-protein kinase Lyn (EC 2.7.10.2)| Length = 511 Score = 43.5 bits (101), Expect = 5e-04 Identities = 34/120 (28%), Positives = 57/120 (47%), Gaps = 1/120 (0%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVVREE 433 + + APE FT KSDV+SFG+L+ E++T GK P + DV+ + + R E Sbjct: 406 IKWTAPEAINFGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNADVMSALSQGYRMPRME 465 Query: 432 WTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTASESR 253 N DEL ++++ C + RPT + +++D +TA+E + Sbjct: 466 --------------NCPDELYDIMKM---CWKEKAEERPTFDYLQSVLDDF--YTATEGQ 506
>INSRR_CAVPO (P14617) Insulin receptor-related protein precursor (EC 2.7.10.1)| (IRR) (IR-related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain] Length = 1300 Score = 43.5 bits (101), Expect = 5e-04 Identities = 31/109 (28%), Positives = 53/109 (48%), Gaps = 1/109 (0%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVVREE 433 V + APE+ + FT SDV+SFGV++ E++T + P Q E V+ Sbjct: 1156 VRWMAPESLKDGIFTTHSDVWSFGVVLWEIVTLAEQPYQGLSNEQVLKF----------- 1204 Query: 432 WTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIE 286 V D +++ +ED Q+ +L +C + P RPT +++ I+ Sbjct: 1205 ----VMDGGVLE--ELEDCPHQLQELMSSCWQQNPRLRPTFTQILNSIQ 1247
>KYK1_DICDI (P18160) Non-receptor tyrosine kinase spore lysis A (EC 2.7.10.2)| (Tyrosine-protein kinase 1) Length = 1584 Score = 43.1 bits (100), Expect = 7e-04 Identities = 28/110 (25%), Positives = 51/110 (46%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDVIDLPRWVHSVVREEW 430 + Y APE ++ + KSDVYS+G+++ E+LT P Q+D+ + + H E + Sbjct: 1469 IPYMAPEVFKGDSNSEKSDVYSYGMVLFELLTSDEP-----QQDMKPM-KMAHLAAYESY 1522 Query: 429 TAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDL 280 + K+ I + C PD RPT ++I ++++ Sbjct: 1523 RPPIPLTTSSKWKEILTQ----------CWDSNPDSRPTFKQIIVHLKEM 1562
>TOR_DROME (P18475) Tyrosine-protein kinase receptor torso precursor (EC| 2.7.10.1) Length = 923 Score = 43.1 bits (100), Expect = 7e-04 Identities = 30/107 (28%), Positives = 49/107 (45%), Gaps = 1/107 (0%) Frame = -3 Query: 624 TSRVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHS 448 + ++ + + A E+ + +T +SDV+SFGVL+ E+ T G P S D++ L R H Sbjct: 778 SGKLPIKWLALESLTHQVYTSQSDVWSFGVLLYEITTLGGMPYPSVSPSDLLQLLRQGHR 837 Query: 447 VVREEWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMA 307 + R E + +M L +C S P RPT + Sbjct: 838 MKRPEGCTQ-----------------EMFSLMESCWSSVPSHRPTFS 867
>SRMS_HUMAN (Q9H3Y6) Tyrosine-protein kinase Srms (EC 2.7.10.2)| Length = 488 Score = 42.7 bits (99), Expect = 9e-04 Identities = 21/55 (38%), Positives = 34/55 (61%), Gaps = 1/55 (1%) Frame = -3 Query: 633 PINTSRVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVI 472 P ++S++ V + APE R F+ KSDV+SFGVL+ E+ T G+ P + + + Sbjct: 382 PSSSSKIPVKWTAPEAANYRVFSQKSDVWSFGVLLHEVFTYGQCPYEGMTNHETL 436
>EPHA5_CHICK (P54755) Ephrin type-A receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor CEK7) Length = 1013 Score = 42.7 bits (99), Expect = 9e-04 Identities = 34/134 (25%), Positives = 62/134 (46%), Gaps = 1/134 (0%) Frame = -3 Query: 618 RVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVV 442 ++ + + APE RKFT SDV+S+G+++ E+++ G+ P +DVI V Sbjct: 815 KIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVMSYGERPYWEMTNQDVI-------KAV 867 Query: 441 REEWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTAS 262 E + + + D + QL + C + + RP E++ M++ L + S Sbjct: 868 EEGY----------RLPSPMDCPAALYQLMLDCWQKDRNSRPKFDEIVSMLDKLIR-NPS 916 Query: 261 ESRASSNENPRDSN 220 + N + R SN Sbjct: 917 SLKTLVNASSRVSN 930
>FGFR3_MOUSE (Q61851) Fibroblast growth factor receptor 3 precursor (EC| 2.7.10.1) (FGFR-3) (Heparin-binding growth factor receptor) Length = 801 Score = 42.7 bits (99), Expect = 9e-04 Identities = 31/122 (25%), Positives = 56/122 (45%), Gaps = 2/122 (1%) Frame = -3 Query: 618 RVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT--GKAPLQSQGQEDVIDLPRWVHSV 445 R+ V + APE R +TH+SDV+SFGVL+ E+ T G +P E++ L + H + Sbjct: 649 RLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTPGGPSPYPGIPVEELFKLLKEGHRM 708 Query: 444 VREEWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTA 265 D H+ + + C P +RPT +++ ++ + T+ Sbjct: 709 ----------DKPASCTHD-------LYMIMRECWHAVPSQRPTFKQLVEDLDRILTVTS 751 Query: 264 SE 259 ++ Sbjct: 752 TD 753
>KS6AB_XENLA (P10666) Ribosomal protein S6 kinase 2 beta (EC 2.7.11.1)| (Ribosomal protein S6 kinase II beta) (S6KII-beta) (P90-RSK) Length = 629 Score = 42.7 bits (99), Expect = 9e-04 Identities = 19/48 (39%), Positives = 30/48 (62%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDVIDL 466 V Y APE + +H +D +S+GVL+ EMLTG P Q + +++ + L Sbjct: 226 VEYMAPEVVNRQGHSHGADWWSYGVLMFEMLTGSLPFQGKDRKETMTL 273
>YES_AVISY (P00527) Tyrosine-protein kinase transforming protein YES (EC| 2.7.10.2) (Fragment) Length = 528 Score = 42.7 bits (99), Expect = 9e-04 Identities = 32/118 (27%), Positives = 53/118 (44%), Gaps = 1/118 (0%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVVREE 433 + + APE +FT KSDV+SFG+L+ E++T G+ P +V++ + + + Sbjct: 426 IKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMVNREVLEQVERGYRMPCPQ 485 Query: 432 WTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTASE 259 E + +L C + PD RPT + +ED FTA+E Sbjct: 486 GCPE-----------------SLHELMKLCWKKDPDERPTFEYIQSFLED--YFTAAE 524
>KPCD_HUMAN (Q05655) Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta)| Length = 676 Score = 42.7 bits (99), Expect = 9e-04 Identities = 20/58 (34%), Positives = 32/58 (55%), Gaps = 8/58 (13%) Frame = -3 Query: 603 YRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDVID--------LPRWV 454 Y APE + K+T D +SFGVL+ EML G++P ++++ + PRW+ Sbjct: 514 YIAPEILQGLKYTFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDTPHYPRWI 571
>TXK_MOUSE (P42682) Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18)| (Resting lymphocyte kinase) Length = 527 Score = 42.7 bits (99), Expect = 9e-04 Identities = 26/108 (24%), Positives = 51/108 (47%), Gaps = 1/108 (0%) Frame = -3 Query: 594 PETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVVREEWTAEV 418 PE + K++ KSDV+SFGVL+ E+ T GK P +++ V++ + R Sbjct: 435 PEVFHFNKYSSKSDVWSFGVLMWEVFTEGKMPFENKSNLQVVEAISQGFRLYRPHLAP-- 492 Query: 417 FDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQ 274 + + ++ +C P RPT AE+++++ ++ + Sbjct: 493 ---------------MTIYRVMYSCWHESPKGRPTFAELLQVLTEIAE 525
>EPHB5_CHICK (Q07497) Ephrin type-B receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase CEK9) Length = 1002 Score = 42.7 bits (99), Expect = 9e-04 Identities = 27/101 (26%), Positives = 51/101 (50%), Gaps = 14/101 (13%) Frame = -3 Query: 618 RVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVI---------- 472 ++ + + APE + RKFT SDV+S+G+++ E+++ G+ P +DVI Sbjct: 803 KIPIRWTAPEAVQYRKFTSSSDVWSYGIVMWEVMSYGERPYWDMSNQDVINAIDQDYRLP 862 Query: 471 ---DLPRWVHSVVREEWTAEVFDVALMKYHNIEDELVQMLQ 358 D P +H ++ + W + V K+ I L +M++ Sbjct: 863 PPPDCPTVLHLLMLDCWQKD--RVQRPKFEQIVSALDKMIR 901
>EPHA7_MOUSE (Q61772) Ephrin type-A receptor 7 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Embryonic brain kinase) (EBK) (Developmental kinase 1) (MDK-1) Length = 998 Score = 42.7 bits (99), Expect = 9e-04 Identities = 23/77 (29%), Positives = 41/77 (53%), Gaps = 14/77 (18%) Frame = -3 Query: 618 RVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVI---------- 472 ++ V + APE + RKFT SDV+S+G+++ E+++ G+ P +DVI Sbjct: 797 KIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLP 856 Query: 471 ---DLPRWVHSVVREEW 430 D P +H ++ + W Sbjct: 857 APMDCPAGLHQLMLDCW 873
>ULK1_MOUSE (O70405) Serine/threonine-protein kinase ULK1 (EC 2.7.11.1)| (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1) Length = 1051 Score = 42.7 bits (99), Expect = 9e-04 Identities = 18/43 (41%), Positives = 28/43 (65%) Frame = -3 Query: 603 YRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDV 475 Y APE S+ + K+D++S G +V + LTGKAP Q+ +D+ Sbjct: 187 YMAPEVIMSQHYDGKADLWSIGTIVYQCLTGKAPFQASSPQDL 229
>BYR1_SCHPO (P10506) Protein kinase byr1 (EC 2.7.12.2) (MAPK kinase) (MAPKK)| Length = 340 Score = 42.7 bits (99), Expect = 9e-04 Identities = 19/57 (33%), Positives = 33/57 (57%) Frame = -3 Query: 603 YRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDVIDLPRWVHSVVREE 433 Y +PE K+T KSD++S G+ ++E+ T + P +D I + +H +V+EE Sbjct: 225 YMSPERIRGGKYTVKSDIWSLGISIIELATQELPWSFSNIDDSIGILDLLHCIVQEE 281
>EPHB1_CHICK (Q07494) Ephrin type-B receptor 1 (EC 2.7.10.1) (Tyrosine-protein| kinase receptor EPH-2) (Tyrosine kinase CEK6 receptor) (Fragment) Length = 984 Score = 42.7 bits (99), Expect = 9e-04 Identities = 29/120 (24%), Positives = 59/120 (49%), Gaps = 1/120 (0%) Frame = -3 Query: 618 RVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVV 442 ++ V + APE RKFT SDV+S+G+++ E+++ G+ P +DVI + + Sbjct: 785 KIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVI-------NAI 837 Query: 441 REEWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTAS 262 +++ + D + QL + C + + RP +AE++ ++ + + AS Sbjct: 838 EQDY----------RLPPPMDCPAALHQLMLDCWQKDRNTRPRLAEIVNTLDKMIRNPAS 887
>ULK1_HUMAN (O75385) Serine/threonine-protein kinase ULK1 (EC 2.7.11.1)| (Unc-51-like kinase 1) Length = 1050 Score = 42.7 bits (99), Expect = 9e-04 Identities = 18/43 (41%), Positives = 28/43 (65%) Frame = -3 Query: 603 YRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDV 475 Y APE S+ + K+D++S G +V + LTGKAP Q+ +D+ Sbjct: 187 YMAPEVIMSQHYDGKADLWSIGTIVYQCLTGKAPFQASSPQDL 229
>ERBB2_MOUSE (P70424) Receptor tyrosine-protein kinase erbB-2 precursor (EC| 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) Length = 1256 Score = 42.4 bits (98), Expect = 0.001 Identities = 35/134 (26%), Positives = 62/134 (46%), Gaps = 2/134 (1%) Frame = -3 Query: 618 RVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVV 442 +V + + A E+ R+FTH+SDV+S+GV V E++T G P ++ DL + Sbjct: 884 KVPIKWMALESILRRRFTHQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLP 943 Query: 441 REE-WTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTA 265 + T +V+ + +V+ + C RF R ++E RM D ++F Sbjct: 944 QPPICTIDVYMI-----------MVKCWMIDSECRPRF---RELVSEFSRMARDPQRFVV 989 Query: 264 SESRASSNENPRDS 223 ++ +P DS Sbjct: 990 IQNEDLGPSSPMDS 1003
>ERBB2_RAT (P06494) Receptor tyrosine-protein kinase erbB-2 precursor (EC| 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Epidermal growth factor receptor-related protein) Length = 1257 Score = 42.4 bits (98), Expect = 0.001 Identities = 35/134 (26%), Positives = 62/134 (46%), Gaps = 2/134 (1%) Frame = -3 Query: 618 RVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVV 442 +V + + A E+ R+FTH+SDV+S+GV V E++T G P ++ DL + Sbjct: 885 KVPIKWMALESILRRRFTHQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLP 944 Query: 441 REE-WTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTA 265 + T +V+ + +V+ + C RF R ++E RM D ++F Sbjct: 945 QPPICTIDVYMI-----------MVKCWMIDSECRPRF---RELVSEFSRMARDPQRFVV 990 Query: 264 SESRASSNENPRDS 223 ++ +P DS Sbjct: 991 IQNEDLGPSSPMDS 1004
>SRC_RAT (Q9WUD9) Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2)| (p60-Src) (c-Src) (pp60c-src) Length = 535 Score = 42.4 bits (98), Expect = 0.001 Identities = 35/127 (27%), Positives = 54/127 (42%), Gaps = 2/127 (1%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVID-LPRWVHSVVRE 436 + + APE +FT KSDV+SFG+L+ E+ T G+ P +V+D + R Sbjct: 428 IKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPP 487 Query: 435 EWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTASES 256 E + D L C + P+ RPT + +ED FT++E Sbjct: 488 ECPESLHD------------------LMCQCWRKEPEERPTFEYLQAFLED--YFTSTER 527 Query: 255 RASSNEN 235 + EN Sbjct: 528 QYQPGEN 534
>SRC_HUMAN (P12931) Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2)| (p60-Src) (c-Src) (pp60c-src) Length = 535 Score = 42.4 bits (98), Expect = 0.001 Identities = 35/127 (27%), Positives = 54/127 (42%), Gaps = 2/127 (1%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVID-LPRWVHSVVRE 436 + + APE +FT KSDV+SFG+L+ E+ T G+ P +V+D + R Sbjct: 428 IKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPP 487 Query: 435 EWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTASES 256 E + D L C + P+ RPT + +ED FT++E Sbjct: 488 ECPESLHD------------------LMCQCWRKEPEERPTFEYLQAFLED--YFTSTEP 527 Query: 255 RASSNEN 235 + EN Sbjct: 528 QYQPGEN 534
>EPA4A_XENLA (Q91845) Ephrin type-A receptor 4-A precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor SEK-1) (xSEK-1) Length = 986 Score = 42.4 bits (98), Expect = 0.001 Identities = 34/150 (22%), Positives = 68/150 (45%), Gaps = 4/150 (2%) Frame = -3 Query: 618 RVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVV 442 ++ + + APE RKFT SDV+S+G+++ E+++ G+ P +DVI + Sbjct: 784 KIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVI-------KAI 836 Query: 441 REEWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTAS 262 E + + D + + QL + C + RP +++ M++ L + S Sbjct: 837 EEGY----------RLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVSMLDKLIRNPNS 886 Query: 261 ESRASSNENPRDSN---PPSA*CWVWLATL 181 R + + R + PS+ W +A++ Sbjct: 887 LKRTGLDNSSRTNTTLLDPSSPEWSQVASV 916
>SRC_CHICK (P00523) Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2)| (p60-Src) (c-Src) (pp60c-src) Length = 532 Score = 42.4 bits (98), Expect = 0.001 Identities = 35/127 (27%), Positives = 54/127 (42%), Gaps = 2/127 (1%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVID-LPRWVHSVVRE 436 + + APE +FT KSDV+SFG+L+ E+ T G+ P +V+D + R Sbjct: 425 IKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPP 484 Query: 435 EWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTASES 256 E + D L C + P+ RPT + +ED FT++E Sbjct: 485 ECPESLHD------------------LMCQCWRKDPEERPTFEYLQAFLED--YFTSTEP 524 Query: 255 RASSNEN 235 + EN Sbjct: 525 QYQPGEN 531
>SRC_MOUSE (P05480) Neuronal proto-oncogene tyrosine-protein kinase Src (EC| 2.7.10.2) (p60-Src) (c-Src) (pp60c-src) Length = 540 Score = 42.4 bits (98), Expect = 0.001 Identities = 35/127 (27%), Positives = 54/127 (42%), Gaps = 2/127 (1%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVID-LPRWVHSVVRE 436 + + APE +FT KSDV+SFG+L+ E+ T G+ P +V+D + R Sbjct: 433 IKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPP 492 Query: 435 EWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTASES 256 E + D L C + P+ RPT + +ED FT++E Sbjct: 493 ECPESLHD------------------LMCQCWRKEPEERPTFEYLQAFLED--YFTSTEP 532 Query: 255 RASSNEN 235 + EN Sbjct: 533 QYQPGEN 539
>EPHB3_BRARE (O13147) Ephrin type-B receptor 3 (EC 2.7.10.1) (Tyrosine-protein| kinase receptor ZEK3) (EPH-like kinase 3) (Fragment) Length = 500 Score = 42.4 bits (98), Expect = 0.001 Identities = 23/80 (28%), Positives = 41/80 (51%), Gaps = 14/80 (17%) Frame = -3 Query: 618 RVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDV----------- 475 ++ + + APE RKFT SDV+S+G+++ E+++ G+ P +DV Sbjct: 353 KIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVMNAVEQDYRLP 412 Query: 474 --IDLPRWVHSVVREEWTAE 421 +D P +H ++ E W E Sbjct: 413 PPMDCPAVLHQLMLECWVKE 432
>YES_XENLA (P10936) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 536 Score = 42.4 bits (98), Expect = 0.001 Identities = 32/126 (25%), Positives = 55/126 (43%), Gaps = 1/126 (0%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVVREE 433 + + APE +FT KSDV+SFG+L+ E++ G+ P +V++ + + + Sbjct: 429 IKWTAPEAALYGRFTIKSDVWSFGILLTELVAKGRVPYPGMVNREVLEQVERGYRMPCPQ 488 Query: 432 WTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTASESR 253 E + +L C + PD RPT + +ED FTA+E + Sbjct: 489 RCPE-----------------SLHELMKLCWKKDPDERPTFEYIQSFLED--YFTATEPQ 529 Query: 252 ASSNEN 235 +N Sbjct: 530 YQPGDN 535
>VGFR3_HUMAN (P35916) Vascular endothelial growth factor receptor 3 precursor (EC| 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4) Length = 1298 Score = 42.4 bits (98), Expect = 0.001 Identities = 33/135 (24%), Positives = 62/135 (45%), Gaps = 1/135 (0%) Frame = -3 Query: 624 TSRVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHS 448 ++R+ + + APE+ + +T +SDV+SFGVL+ E+ + G +P + Sbjct: 1073 SARLPLKWMAPESIFDKVYTTQSDVWSFGVLLWEIFSLGASP--------------YPGV 1118 Query: 447 VVREEWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFT 268 + EE+ + D M+ + ++ + L C S P RP +E++ ++ DL Q Sbjct: 1119 QINEEFCQRLRDGTRMRAPELATPAIRRIML--NCWSGDPKARPAFSELVEILGDLLQGR 1176 Query: 267 ASESRASSNENPRDS 223 + PR S Sbjct: 1177 GLQEEEEVCMAPRSS 1191
>PKPA_PHYBL (Q01577) Serine/threonine-protein kinase pkpA (EC 2.7.11.1)| Length = 613 Score = 42.0 bits (97), Expect = 0.002 Identities = 25/80 (31%), Positives = 42/80 (52%), Gaps = 4/80 (5%) Frame = -3 Query: 603 YRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDVIDLPRWVHSVVREEWTA 424 + APE YE + + K D+Y+FG+ ++EM TG+ P + + + + V ++ E + Sbjct: 179 FMAPEMYEEQGYNEKVDIYAFGMCLLEMATGEYPYGE--CTNAVQVFKKVTQTIKPECLS 236 Query: 423 EVFDVALMKYHNI----EDE 376 V D L+ NI EDE Sbjct: 237 RVQDPELLTLVNICLTPEDE 256
>EPA4A_BRARE (O13148) Ephrin type-A receptor 4a (EC 2.7.10.1) (Tyrosine-protein| kinase receptor ZEK2) (EPH-like kinase 2) (Fragment) Length = 292 Score = 42.0 bits (97), Expect = 0.002 Identities = 28/114 (24%), Positives = 54/114 (47%), Gaps = 1/114 (0%) Frame = -3 Query: 618 RVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVV 442 ++ + + APE RKFT SDV+S+G+++ E+++ G+ P +DVI + Sbjct: 168 KIPIRWTAPEAITYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVI-------KAI 220 Query: 441 REEWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDL 280 E + + D V + QL + C + RP ++++ M++ L Sbjct: 221 EEGY----------RLPPPMDCPVSLHQLMLDCWQKERAERPKFSQIVNMLDKL 264
>SRK3_SPOLA (P42689) Tyrosine-protein kinase SRK3 (EC 2.7.10.2) (Fragment)| Length = 334 Score = 42.0 bits (97), Expect = 0.002 Identities = 29/118 (24%), Positives = 52/118 (44%), Gaps = 1/118 (0%) Frame = -3 Query: 633 PINTSRVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRW 457 P ++ + + APE +FT KSDV+SFGVL+ E++T G+ P V++ Sbjct: 218 PREGTKFPIKWTAPEAALYNRFTIKSDVWSFGVLISEIVTHGRMPYPGMTNRQVLEAVDR 277 Query: 456 VHSVVREEWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIED 283 + + E + + ++ ++C PD RPT + ++ED Sbjct: 278 GYRMPCPEGCPD-----------------PLYKIMLSCWKHEPDDRPTFESLKNLLED 318
>EPHA5_MOUSE (Q60629) Ephrin type-A receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Brain-specific kinase) (CEK-7) Length = 877 Score = 42.0 bits (97), Expect = 0.002 Identities = 29/114 (25%), Positives = 54/114 (47%), Gaps = 1/114 (0%) Frame = -3 Query: 618 RVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVV 442 ++ + + APE RKFT SDV+S+G+++ E+++ G+ P +DVI V Sbjct: 678 KIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVI-------KAV 730 Query: 441 REEWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDL 280 E + + + D + QL + C + + RP E++ M++ L Sbjct: 731 EEGY----------RLPSPMDCPAALYQLMLDCWQKDRNSRPKFDEIVNMLDKL 774
>EPHA5_HUMAN (P54756) Ephrin type-A receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Receptor protein-tyrosine kinase HEK7) Length = 1037 Score = 42.0 bits (97), Expect = 0.002 Identities = 29/114 (25%), Positives = 54/114 (47%), Gaps = 1/114 (0%) Frame = -3 Query: 618 RVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVV 442 ++ + + APE RKFT SDV+S+G+++ E+++ G+ P +DVI V Sbjct: 839 KIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVI-------KAV 891 Query: 441 REEWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDL 280 E + + + D + QL + C + + RP E++ M++ L Sbjct: 892 EEGY----------RLPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKL 935
>YR831_MIMIV (Q7T6Y2) Putative serine/threonine-protein kinase/receptor R831| precursor (EC 2.7.11.1) Length = 1624 Score = 42.0 bits (97), Expect = 0.002 Identities = 29/96 (30%), Positives = 44/96 (45%), Gaps = 13/96 (13%) Frame = -3 Query: 603 YRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQS-----------QGQEDVI--DLP 463 + APE K+ K+DV+SFGV++ E+LTGK P +G +I D P Sbjct: 1526 WTAPEVIRGEKYCEKADVFSFGVVMWEVLTGKEPFAECNFMKVSLDILEGGRPIIPSDCP 1585 Query: 462 RWVHSVVREEWTAEVFDVALMKYHNIEDELVQMLQL 355 ++++ W A+ M E+VQ L L Sbjct: 1586 HEFAKLIKKCWHAKAHKRPTM------TEVVQQLML 1615 Score = 32.7 bits (73), Expect = 0.93 Identities = 25/108 (23%), Positives = 51/108 (47%) Frame = -3 Query: 558 SDVYSFGVLVMEMLTGKAPLQSQGQEDVIDLPRWVHSVVREEWTAEVFDVALMKYHNIED 379 +DVYSFG+++ E+LT + P + + SV+R+ + D A+ H+IE Sbjct: 968 ADVYSFGIILWELLTREQPYKGMTPAAI------AVSVIRDGMRPPISDEAVTA-HSIE- 1019 Query: 378 ELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTASESRASSNEN 235 + L C RPT E++ + ++ +++ + +S+ + Sbjct: 1020 ----YIDLIKQCWHSDTIIRPTFLEIMTRLSNILGDSSNMTSGTSSSS 1063
>EPHB3_CHICK (Q07498) Ephrin type-B receptor 3 (EC 2.7.10.1) (Tyrosine-protein| kinase receptor CEK10) (Fragment) Length = 988 Score = 42.0 bits (97), Expect = 0.002 Identities = 30/120 (25%), Positives = 58/120 (48%), Gaps = 1/120 (0%) Frame = -3 Query: 618 RVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVV 442 ++ + + APE RKFT SDV+S+G+++ E+++ G+ P +DVI + V Sbjct: 789 KIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVI-------NAV 841 Query: 441 REEWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTAS 262 +++ + D + QL + C R + RP A+++ ++ L + AS Sbjct: 842 EQDY----------RLPPPMDCPTALHQLMLDCWVRDRNLRPKFAQIVNTLDKLIRNAAS 891
>IPL1_YEAST (P38991) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) (Increase-in-ploidy protein 1) Length = 367 Score = 42.0 bits (97), Expect = 0.002 Identities = 20/51 (39%), Positives = 29/51 (56%), Gaps = 3/51 (5%) Frame = -3 Query: 633 PINTSRVVVG---YRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQ 490 P N + V G Y +PE ESR++ H D ++ GVL E+LTG P + + Sbjct: 254 PENRRKTVCGTIDYLSPEMVESREYDHTIDAWALGVLAFELLTGAPPFEEE 304
>MIPR_LYMST (Q25410) Putative molluscan insulin-related peptide(s) receptor| precursor (EC 2.7.10.1) [Contains: Putative molluscan insulin-related peptide(s) receptor alpha chain; Putative molluscan insulin-related peptide(s) receptor beta chain] Length = 1607 Score = 42.0 bits (97), Expect = 0.002 Identities = 31/109 (28%), Positives = 54/109 (49%), Gaps = 2/109 (1%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKA-PLQSQGQEDVIDLPRWVHSVVREE 433 V + APE+ + FT SDV+S+GV++ EM+T A P Q E+V+ Sbjct: 1214 VRWMAPESLKDGVFTSLSDVWSYGVVMWEMVTLAAQPYQGLSNEEVVKF----------- 1262 Query: 432 WTAEVFDVALMKY-HNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMI 289 + D +M+ N +E+ ++Q C ++ P++RPT +I + Sbjct: 1263 ----ISDGYIMELPENCPNEMAYLMQ---HCWAKKPNQRPTFKAIIEYL 1304
>EPHA4_MOUSE (Q03137) Ephrin type-A receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor SEK) (MPK-3) Length = 986 Score = 42.0 bits (97), Expect = 0.002 Identities = 30/129 (23%), Positives = 58/129 (44%), Gaps = 1/129 (0%) Frame = -3 Query: 618 RVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVV 442 ++ + + APE RKFT SDV+S+G+++ E+++ G+ P +DVI + Sbjct: 785 KIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVI-------KAI 837 Query: 441 REEWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTAS 262 E + + D + + QL + C + RP +++ M++ L + S Sbjct: 838 EEGY----------RLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNMLDKLIRNPNS 887 Query: 261 ESRASSNEN 235 R S + Sbjct: 888 LKRTGSESS 896
>EPHA4_CHICK (Q07496) Ephrin type-A receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor CEK8) Length = 986 Score = 42.0 bits (97), Expect = 0.002 Identities = 30/129 (23%), Positives = 58/129 (44%), Gaps = 1/129 (0%) Frame = -3 Query: 618 RVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVV 442 ++ + + APE RKFT SDV+S+G+++ E+++ G+ P +DVI + Sbjct: 785 KIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVI-------KAI 837 Query: 441 REEWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTAS 262 E + + D + + QL + C + RP +++ M++ L + S Sbjct: 838 EEGY----------RLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNMLDKLIRNPNS 887 Query: 261 ESRASSNEN 235 R S + Sbjct: 888 LKRTGSESS 896
>EPHB1_RAT (P09759) Ephrin type-B receptor 1 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-2) (ELK) Length = 984 Score = 42.0 bits (97), Expect = 0.002 Identities = 29/120 (24%), Positives = 58/120 (48%), Gaps = 1/120 (0%) Frame = -3 Query: 618 RVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVV 442 ++ V + APE RKFT SDV+S+G+++ E+++ G+ P +DVI + + Sbjct: 785 KIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVI-------NAI 837 Query: 441 REEWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTAS 262 +++ + D + QL + C + + RP AE++ ++ + + AS Sbjct: 838 EQDY----------RLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKMIRNPAS 887
>EPHB1_HUMAN (P54762) Ephrin type-B receptor 1 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK) Length = 984 Score = 42.0 bits (97), Expect = 0.002 Identities = 29/120 (24%), Positives = 58/120 (48%), Gaps = 1/120 (0%) Frame = -3 Query: 618 RVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVV 442 ++ V + APE RKFT SDV+S+G+++ E+++ G+ P +DVI + + Sbjct: 785 KIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVI-------NAI 837 Query: 441 REEWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTAS 262 +++ + D + QL + C + + RP AE++ ++ + + AS Sbjct: 838 EQDY----------RLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKMIRNPAS 887
>KPC1_CAEEL (P34722) Protein kinase C-like 1 (EC 2.7.11.13) (PKC)| (Tetradecanoyl phorbol acetate resistant protein 1) Length = 704 Score = 41.6 bits (96), Expect = 0.002 Identities = 16/45 (35%), Positives = 29/45 (64%) Frame = -3 Query: 603 YRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDVID 469 Y +PE + + + D +SFGVL+ EML G++P +G++++ D Sbjct: 541 YISPEIIKGQLYNEAVDFWSFGVLMYEMLVGQSPFHGEGEDELFD 585
>ERBB2_HUMAN (P04626) Receptor tyrosine-protein kinase erbB-2 precursor (EC| 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19) Length = 1255 Score = 41.6 bits (96), Expect = 0.002 Identities = 35/134 (26%), Positives = 62/134 (46%), Gaps = 2/134 (1%) Frame = -3 Query: 618 RVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVV 442 +V + + A E+ R+FTH+SDV+S+GV V E++T G P ++ DL + Sbjct: 883 KVPIKWMALESILRRRFTHQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLP 942 Query: 441 REE-WTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTA 265 + T +V+ + +V+ + C RF R ++E RM D ++F Sbjct: 943 QPPICTIDVYMI-----------MVKCWMIDSECRPRF---RELVSEFSRMARDPQRFVV 988 Query: 264 SESRASSNENPRDS 223 ++ +P DS Sbjct: 989 IQNEDLGPASPLDS 1002
>PKNA2_BIFLO (Q8G4G1) Probable serine/threonine-protein kinase pknA2 (EC| 2.7.11.1) Length = 757 Score = 41.6 bits (96), Expect = 0.002 Identities = 18/37 (48%), Positives = 24/37 (64%) Frame = -3 Query: 603 YRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQS 493 Y APE E+ + T + D+YS G++ EMLTGK P S Sbjct: 182 YLAPEMIENNQATAQGDLYSVGIMAWEMLTGKVPFDS 218
>EPHA4_HUMAN (P54764) Ephrin type-A receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8) Length = 986 Score = 41.6 bits (96), Expect = 0.002 Identities = 24/83 (28%), Positives = 42/83 (50%), Gaps = 14/83 (16%) Frame = -3 Query: 618 RVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVI---------- 472 ++ + + APE RKFT SDV+S+G+++ E+++ G+ P +DVI Sbjct: 785 KIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLP 844 Query: 471 ---DLPRWVHSVVREEWTAEVFD 412 D P +H ++ + W E D Sbjct: 845 PPMDCPIALHQLMLDCWQKERSD 867
>SRC2_XENLA (P13116) Tyrosine-protein kinase Src-2 (EC 2.7.10.2) (p60-Src-2)| Length = 531 Score = 41.6 bits (96), Expect = 0.002 Identities = 34/127 (26%), Positives = 54/127 (42%), Gaps = 2/127 (1%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVID-LPRWVHSVVRE 436 + + APE +FT KSDV+SFG+L+ E+ T G+ P +V+D + R Sbjct: 424 IKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPP 483 Query: 435 EWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTASES 256 + + D L C + P+ RPT + +ED FTA+E Sbjct: 484 DCPESLHD------------------LMFQCWRKDPEERPTFEYLQAFLED--YFTATEP 523 Query: 255 RASSNEN 235 + +N Sbjct: 524 QYQPGDN 530
>SRC1_XENLA (P13115) Tyrosine-protein kinase Src-1 (EC 2.7.10.2) (p60-Src-1)| Length = 531 Score = 41.6 bits (96), Expect = 0.002 Identities = 34/127 (26%), Positives = 54/127 (42%), Gaps = 2/127 (1%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVID-LPRWVHSVVRE 436 + + APE +FT KSDV+SFG+L+ E+ T G+ P +V+D + R Sbjct: 424 IKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPP 483 Query: 435 EWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTASES 256 + + D L C + P+ RPT + +ED FTA+E Sbjct: 484 DCPESLHD------------------LMFQCWRKDPEERPTFEYLQAFLED--YFTATEP 523 Query: 255 RASSNEN 235 + +N Sbjct: 524 QYQPGDN 530
>EPHB2_COTJA (Q90344) Ephrin type-B receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor QEK5) Length = 987 Score = 41.6 bits (96), Expect = 0.002 Identities = 22/77 (28%), Positives = 41/77 (53%), Gaps = 14/77 (18%) Frame = -3 Query: 618 RVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVI---------- 472 ++ + + APE + RKFT SDV+S+G+++ E+++ G+ P +DVI Sbjct: 788 KIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRLP 847 Query: 471 ---DLPRWVHSVVREEW 430 D P +H ++ + W Sbjct: 848 PPMDCPNALHQLMLDCW 864
>ABL_MLVAB (P00521) Tyrosine-protein kinase transforming protein Abl (EC| 2.7.10.2) (V-abl) Length = 746 Score = 41.6 bits (96), Expect = 0.002 Identities = 32/113 (28%), Positives = 51/113 (45%), Gaps = 1/113 (0%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVVREE 433 + + APE+ KF+ KSDV++FGVL+ E+ T G +P V +L + + R E Sbjct: 289 IKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPE 348 Query: 432 WTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQ 274 E ++ +L AC P RP+ AE+ + E + Q Sbjct: 349 GCPE-----------------KVYELMRACWQWNPSDRPSFAEIHQAFETMFQ 384
>NTRK1_HUMAN (P04629) High affinity nerve growth factor receptor precursor (EC| 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1 transforming tyrosine kinase protein) (p140-TrkA) (Trk-A) Length = 796 Score = 41.6 bits (96), Expect = 0.002 Identities = 31/102 (30%), Positives = 49/102 (48%), Gaps = 14/102 (13%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVID------------ 469 + + PE+ RKFT +SDV+SFGV++ E+ T GK P + ID Sbjct: 691 IRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPR 750 Query: 468 -LPRWVHSVVREEWTAEVFDVALMKYHNIEDELVQMLQLAMA 346 P V++++R W E + H+I+D ++ LA A Sbjct: 751 ACPPEVYAIMRGCWQREP-----QQRHSIKDVHARLQALAQA 787
>SRMS_MOUSE (Q62270) Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70)| Length = 496 Score = 41.6 bits (96), Expect = 0.002 Identities = 20/55 (36%), Positives = 33/55 (60%), Gaps = 1/55 (1%) Frame = -3 Query: 633 PINTSRVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVI 472 P + S++ V + APE R F+ KSDV+SFG+L+ E+ T G+ P + + + Sbjct: 386 PSSGSKIPVKWTAPEAANYRVFSQKSDVWSFGILLYEVFTYGQCPYEGMTNHETL 440
>SRC42_DROME (Q9V9J3) Tyrosine-protein kinase Src42A (EC 2.7.10.2) (Dsrc41)| Length = 517 Score = 41.6 bits (96), Expect = 0.002 Identities = 33/123 (26%), Positives = 57/123 (46%), Gaps = 1/123 (0%) Frame = -3 Query: 621 SRVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSV 445 +R + + APE KF+ KSDV+SFG+L+ E++T G+ P +V+ Sbjct: 406 ARFPIKWTAPEAANYSKFSIKSDVWSFGILLTELVTYGRIPYPGMTNAEVL--------- 456 Query: 444 VREEWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTA 265 T + + N E L +++ + C + P RRPT + +ED +T+ Sbjct: 457 -----TQVEHGYRMPQPPNCEPRLYEIM---LECWHKDPMRRPTFETLQWKLEDF--YTS 506 Query: 264 SES 256 +S Sbjct: 507 DQS 509
>ABL1_HUMAN (P00519) Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2)| (p150) (c-ABL) (Abelson murine leukemia viral oncogene homolog 1) Length = 1130 Score = 41.6 bits (96), Expect = 0.002 Identities = 32/113 (28%), Positives = 51/113 (45%), Gaps = 1/113 (0%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVVREE 433 + + APE+ KF+ KSDV++FGVL+ E+ T G +P V +L + + R E Sbjct: 403 IKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPE 462 Query: 432 WTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQ 274 E ++ +L AC P RP+ AE+ + E + Q Sbjct: 463 GCPE-----------------KVYELMRACWQWNPSDRPSFAEIHQAFETMFQ 498
>TOPK_BRARE (Q6DHU8) T-lymphokine-activated killer cell-originated protein| kinase homolog (EC 2.7.12.2) (PDZ-binding kinase) Length = 339 Score = 41.6 bits (96), Expect = 0.002 Identities = 25/116 (21%), Positives = 54/116 (46%), Gaps = 4/116 (3%) Frame = -3 Query: 603 YRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAP----LQSQGQEDVIDLPRWVHSVVRE 436 ++ E E T K+D++++G+ + EM+T P L ++G ED D + + Sbjct: 215 WKPKEALEDGVITDKADIFAYGLTLWEMMTLSVPHLEMLDTEGDEDDDD-ESFEEDFDED 273 Query: 435 EWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFT 268 + + + + +M++L CT P +RP+ A +++++E Q + Sbjct: 274 AYYERLGSRPALDAVTLGGSYQRMVELFCLCTEEDPQKRPSAAHIVQVLESNSQLS 329
>EPB1B_XENLA (Q91736) Ephrin type-B receptor 1-B (EC 2.7.10.1) (Tyrosine-protein| kinase receptor XELK) (Fragment) Length = 902 Score = 41.6 bits (96), Expect = 0.002 Identities = 23/77 (29%), Positives = 40/77 (51%), Gaps = 14/77 (18%) Frame = -3 Query: 618 RVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVI---------- 472 ++ V + APE RKFT SDV+S+G+++ E+++ G+ P +DVI Sbjct: 703 KIPVRWTAPEAIRYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAIEQDYRLP 762 Query: 471 ---DLPRWVHSVVREEW 430 D P +H ++ + W Sbjct: 763 PPMDCPAALHQLMLDCW 779
>RON_HUMAN (Q04912) Macrophage-stimulating protein receptor precursor (EC| 2.7.10.1) (MSP receptor) (p185-Ron) (CDw136 antigen) [Contains: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain] Length = 1400 Score = 41.6 bits (96), Expect = 0.002 Identities = 35/114 (30%), Positives = 54/114 (47%) Frame = -3 Query: 621 SRVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDVIDLPRWVHSVV 442 +R+ V + A E+ ++ +FT KSDV+SFGVL+ E+LT AP D DL ++ Sbjct: 1247 ARLPVKWMALESLQTYRFTTKSDVWSFGVLLWELLTRGAP--PYRHIDPFDLTHFLAQGR 1304 Query: 441 REEWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDL 280 R L + D L Q++Q C P RPT ++ +E + Sbjct: 1305 R-----------LPQPEYCPDSLYQVMQ---QCWEADPAVRPTFRVLVGEVEQI 1344
>KIN16_CAEEL (P34892) Receptor-like tyrosine-protein kinase kin-16 precursor (EC| 2.7.10.1) Length = 495 Score = 41.6 bits (96), Expect = 0.002 Identities = 25/80 (31%), Positives = 45/80 (56%), Gaps = 5/80 (6%) Frame = -3 Query: 615 VVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVVR 439 V V + +PE +++ KFT KSDV+SFG+ + E+ T G+ P E + + ++HS R Sbjct: 362 VPVRWMSPEAFDTMKFTEKSDVWSFGICLYEIFTLGQLPYPDVPSERIYE---YMHSGRR 418 Query: 438 ----EEWTAEVFDVALMKYH 391 + E++D+ + +H Sbjct: 419 CPQPQHCHVELYDLMKLCWH 438
>ABL1_MOUSE (P00520) Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2)| (p150) (c-ABL) (Abelson murine leukemia viral oncogene homolog 1) Length = 1123 Score = 41.6 bits (96), Expect = 0.002 Identities = 32/113 (28%), Positives = 51/113 (45%), Gaps = 1/113 (0%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVVREE 433 + + APE+ KF+ KSDV++FGVL+ E+ T G +P V +L + + R E Sbjct: 403 IKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPE 462 Query: 432 WTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQ 274 E ++ +L AC P RP+ AE+ + E + Q Sbjct: 463 GCPE-----------------KVYELMRACWQWNPSDRPSFAEIHQAFETMFQ 498
>SPKA_SYNY3 (Q9FAB3) Serine/threonine-protein kinase A (EC 2.7.11.1)| Length = 521 Score = 41.6 bits (96), Expect = 0.002 Identities = 17/37 (45%), Positives = 26/37 (70%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPL 499 + Y +PE E ++ +SD+YS GV++ EMLTG+ PL Sbjct: 192 LAYCSPEQMEGKELDSRSDIYSLGVMMYEMLTGEMPL 228
>EPHB2_CHICK (P28693) Ephrin type-B receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor CEK5) Length = 1004 Score = 41.6 bits (96), Expect = 0.002 Identities = 22/77 (28%), Positives = 41/77 (53%), Gaps = 14/77 (18%) Frame = -3 Query: 618 RVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVI---------- 472 ++ + + APE + RKFT SDV+S+G+++ E+++ G+ P +DVI Sbjct: 805 KIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRLP 864 Query: 471 ---DLPRWVHSVVREEW 430 D P +H ++ + W Sbjct: 865 PPMDCPNALHQLMLDCW 881
>GPRK2_DROME (P32866) G protein-coupled receptor kinase 2 (EC 2.7.11.16)| Length = 714 Score = 41.6 bits (96), Expect = 0.002 Identities = 17/43 (39%), Positives = 28/43 (65%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQE 481 VGY APE ++ K+ D +SFG L+ EM+ G+AP + + ++ Sbjct: 473 VGYMAPEVIDNEKYAFSPDWFSFGCLLYEMIEGQAPFRMRKEK 515
>EPHB3_XENLA (Q91735) Ephrin type-B receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor TCK) Length = 974 Score = 41.2 bits (95), Expect = 0.003 Identities = 22/77 (28%), Positives = 40/77 (51%), Gaps = 14/77 (18%) Frame = -3 Query: 618 RVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVI---------- 472 ++ + + APE RKFT SDV+S+G+++ E+++ G+ P +DVI Sbjct: 775 KIPIRWTAPEAISYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAIEQDYRLP 834 Query: 471 ---DLPRWVHSVVREEW 430 D P +H ++ + W Sbjct: 835 PPMDCPSALHQLMLDCW 851
>KPCD_RAT (P09215) Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta)| Length = 673 Score = 41.2 bits (95), Expect = 0.003 Identities = 19/58 (32%), Positives = 32/58 (55%), Gaps = 8/58 (13%) Frame = -3 Query: 603 YRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDVID--------LPRWV 454 Y APE + K++ D +SFGVL+ EML G++P ++++ + PRW+ Sbjct: 512 YIAPEILQGLKYSFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDTPHYPRWI 569
>ERBB2_MESAU (Q60553) Receptor tyrosine-protein kinase erbB-2 precursor (EC| 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) Length = 1254 Score = 41.2 bits (95), Expect = 0.003 Identities = 35/134 (26%), Positives = 62/134 (46%), Gaps = 2/134 (1%) Frame = -3 Query: 618 RVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVV 442 +V + + A E+ R+FTH+SDV+S+GV V E++T G P ++ DL + Sbjct: 883 KVPIKWIALESILRRRFTHQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLP 942 Query: 441 REE-WTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTA 265 + T +V+ + +V+ + C RF R ++E RM D ++F Sbjct: 943 QPPICTIDVYMI-----------MVKCWMIDSECRPRF---RELVSEFSRMARDPQRFVV 988 Query: 264 SESRASSNENPRDS 223 ++ +P DS Sbjct: 989 IQNEDLGPSSPLDS 1002
>KS6A6_HUMAN (Q9UK32) Ribosomal protein S6 kinase alpha-6 (EC 2.7.11.1)| (S6K-alpha 6) (90 kDa ribosomal protein S6 kinase 6) (p90-RSK 6) (Ribosomal S6 kinase 4) (RSK-4) (pp90RSK4) Length = 745 Score = 41.2 bits (95), Expect = 0.003 Identities = 18/48 (37%), Positives = 29/48 (60%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDVIDL 466 V Y APE R + +D +S+GVL+ EMLTG P Q + + + +++ Sbjct: 237 VEYMAPEVVNRRGHSQSADWWSYGVLMFEMLTGTLPFQGKDRNETMNM 284
>KIT_MOUSE (P05532) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 975 Score = 41.2 bits (95), Expect = 0.003 Identities = 34/139 (24%), Positives = 64/139 (46%), Gaps = 4/139 (2%) Frame = -3 Query: 621 SRVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSV 445 +R+ V + APE+ S +T +SDV+S+G+ + E+ + G +P + + + Sbjct: 827 ARLPVKWMAPESIFSCVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKF------YKM 880 Query: 444 VREEWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTA 265 ++E + + + E +M + C P +RPT +V+++IE +Q + Sbjct: 881 IKEGF----------RMVSPEHAPAEMYDVMKTCWDADPLKRPTFKQVVQLIE--KQISD 928 Query: 264 SESRASSNE---NPRDSNP 217 S SN NP NP Sbjct: 929 STKHIYSNLANCNPNPENP 947
>PCK2_SCHPO (P36583) Protein kinase C-like 2 (EC 2.7.11.13)| Length = 1016 Score = 41.2 bits (95), Expect = 0.003 Identities = 18/56 (32%), Positives = 34/56 (60%), Gaps = 3/56 (5%) Frame = -3 Query: 627 NTSRVVVG---YRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDVID 469 NT+ G + APE +++T D ++FGVL+ +ML G++P + + +E++ D Sbjct: 838 NTTATFCGTPEFMAPEILLEQQYTRSVDWWAFGVLIYQMLLGQSPFRGEDEEEIFD 893
>MET_PONPY (Q2IBD8) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1390 Score = 41.2 bits (95), Expect = 0.003 Identities = 19/40 (47%), Positives = 31/40 (77%) Frame = -3 Query: 621 SRVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAP 502 +++ V + A E+ +++KFT KSDV+SFGVL+ E++T AP Sbjct: 1243 AKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAP 1282
>MET_PIG (Q2QLE0) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1381 Score = 41.2 bits (95), Expect = 0.003 Identities = 19/40 (47%), Positives = 31/40 (77%) Frame = -3 Query: 621 SRVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAP 502 +++ V + A E+ +++KFT KSDV+SFGVL+ E++T AP Sbjct: 1243 AKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAP 1282
>MET_PANTR (Q2QLF1) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1390 Score = 41.2 bits (95), Expect = 0.003 Identities = 19/40 (47%), Positives = 31/40 (77%) Frame = -3 Query: 621 SRVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAP 502 +++ V + A E+ +++KFT KSDV+SFGVL+ E++T AP Sbjct: 1243 AKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAP 1282
>MET_HORSE (Q2QLA9) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1381 Score = 41.2 bits (95), Expect = 0.003 Identities = 19/40 (47%), Positives = 31/40 (77%) Frame = -3 Query: 621 SRVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAP 502 +++ V + A E+ +++KFT KSDV+SFGVL+ E++T AP Sbjct: 1243 AKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAP 1282
>MET_CALMO (Q2QLC0) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1381 Score = 41.2 bits (95), Expect = 0.003 Identities = 19/40 (47%), Positives = 31/40 (77%) Frame = -3 Query: 621 SRVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAP 502 +++ V + A E+ +++KFT KSDV+SFGVL+ E++T AP Sbjct: 1243 AKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAP 1282
>MET_CALJA (Q2QLG5) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1381 Score = 41.2 bits (95), Expect = 0.003 Identities = 19/40 (47%), Positives = 31/40 (77%) Frame = -3 Query: 621 SRVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAP 502 +++ V + A E+ +++KFT KSDV+SFGVL+ E++T AP Sbjct: 1243 AKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAP 1282
>MET_MOUSE (P16056) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1379 Score = 41.2 bits (95), Expect = 0.003 Identities = 19/40 (47%), Positives = 31/40 (77%) Frame = -3 Query: 621 SRVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAP 502 +++ V + A E+ +++KFT KSDV+SFGVL+ E++T AP Sbjct: 1241 AKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAP 1280
>EPHB3_MOUSE (P54754) Ephrin type-B receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4) Length = 993 Score = 41.2 bits (95), Expect = 0.003 Identities = 22/80 (27%), Positives = 41/80 (51%), Gaps = 14/80 (17%) Frame = -3 Query: 618 RVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVI---------- 472 ++ + + APE RKFT SDV+S+G+++ E+++ G+ P +DVI Sbjct: 794 KIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAVEQDYRLP 853 Query: 471 ---DLPRWVHSVVREEWTAE 421 D P +H ++ + W + Sbjct: 854 PPMDCPTALHQLMLDCWVRD 873
>CAD96_DROME (Q9VBW3) Tyrosine kinase receptor Cad96Ca precursor (EC 2.7.10.1)| (Cadherin 96Ca) (Tyrosine kinase receptor HD-14) Length = 773 Score = 41.2 bits (95), Expect = 0.003 Identities = 31/114 (27%), Positives = 53/114 (46%), Gaps = 1/114 (0%) Frame = -3 Query: 618 RVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVV 442 ++ + + A E+ F+ KSD++SFG+L+ E++T G P DV+ V Sbjct: 648 KLPIRWMATESLYDNIFSVKSDIWSFGILMWEIVTLGSTPYPGISAADVM-------RKV 700 Query: 441 REEWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDL 280 R+ + E + + +NI C S P RP AE+I+M++ L Sbjct: 701 RDGYRLEKPEHCRRELYNI----------MYYCWSHDPQERPLFAEIIQMLDKL 744
>EPA4B_XENLA (Q91694) Ephrin type-A receptor 4-B precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor PAG) (Pagliaccio) Length = 985 Score = 41.2 bits (95), Expect = 0.003 Identities = 36/150 (24%), Positives = 69/150 (46%), Gaps = 4/150 (2%) Frame = -3 Query: 618 RVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVV 442 ++ + + APE RKFT SDV+S+G+++ E+++ G+ P +DVI + Sbjct: 784 KIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVI-------KAI 836 Query: 441 REEWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTAS 262 E + + D + + QL + C + RP +++ M++ L + S Sbjct: 837 EEGY----------RLPPPMDCPIALHQLMLDCWQKDRSDRPKFGQIVSMLDKLIRNPNS 886 Query: 261 ESRASSNENPRDSN---PPSA*CWVWLATL 181 R + EN R + PS+ W +A++ Sbjct: 887 LKR-TGLENSRTNTALLDPSSPEWSQVASV 915
>EPHB2_HUMAN (P29323) Ephrin type-B receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen) Length = 1055 Score = 41.2 bits (95), Expect = 0.003 Identities = 22/77 (28%), Positives = 41/77 (53%), Gaps = 14/77 (18%) Frame = -3 Query: 618 RVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVI---------- 472 ++ + + APE + RKFT SDV+S+G+++ E+++ G+ P +DVI Sbjct: 787 KIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRLP 846 Query: 471 ---DLPRWVHSVVREEW 430 D P +H ++ + W Sbjct: 847 PPMDCPSALHQLMLDCW 863
>OXSR1_PONPY (Q5R495) Serine/threonine-protein kinase OSR1 (EC 2.7.11.1)| (Oxidative stress-responsive 1 protein) Length = 527 Score = 41.2 bits (95), Expect = 0.003 Identities = 30/109 (27%), Positives = 53/109 (48%), Gaps = 6/109 (5%) Frame = -3 Query: 603 YRAPETYES-RKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDVIDL-----PRWVHSVV 442 + APE E R + K+D++SFG+ +E+ TG AP V+ L P + + V Sbjct: 192 WMAPEVMEQVRGYDFKADIWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPSLETGV 251 Query: 441 REEWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIR 295 +++ L KY +++ + C + P++RPT AE++R Sbjct: 252 QDK-------EMLKKYGKSFRKMISL------CLQKDPEKRPTAAELLR 287
>OXSR1_MOUSE (Q6P9R2) Serine/threonine-protein kinase OSR1 (EC 2.7.11.1)| (Oxidative stress-responsive 1 protein) Length = 527 Score = 41.2 bits (95), Expect = 0.003 Identities = 30/109 (27%), Positives = 53/109 (48%), Gaps = 6/109 (5%) Frame = -3 Query: 603 YRAPETYES-RKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDVIDL-----PRWVHSVV 442 + APE E R + K+D++SFG+ +E+ TG AP V+ L P + + V Sbjct: 192 WMAPEVMEQVRGYDFKADIWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPSLETGV 251 Query: 441 REEWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIR 295 +++ L KY +++ + C + P++RPT AE++R Sbjct: 252 QDK-------EMLKKYGKSFRKMISL------CLQKDPEKRPTAAELLR 287
>OXSR1_HUMAN (O95747) Serine/threonine-protein kinase OSR1 (EC 2.7.11.1)| (Oxidative stress-responsive 1 protein) Length = 527 Score = 41.2 bits (95), Expect = 0.003 Identities = 30/109 (27%), Positives = 53/109 (48%), Gaps = 6/109 (5%) Frame = -3 Query: 603 YRAPETYES-RKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDVIDL-----PRWVHSVV 442 + APE E R + K+D++SFG+ +E+ TG AP V+ L P + + V Sbjct: 192 WMAPEVMEQVRGYDFKADIWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPSLETGV 251 Query: 441 REEWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIR 295 +++ L KY +++ + C + P++RPT AE++R Sbjct: 252 QDK-------EMLKKYGKSFRKMISL------CLQKDPEKRPTAAELLR 287
>MET_RAT (P97523) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1382 Score = 41.2 bits (95), Expect = 0.003 Identities = 19/40 (47%), Positives = 31/40 (77%) Frame = -3 Query: 621 SRVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAP 502 +++ V + A E+ +++KFT KSDV+SFGVL+ E++T AP Sbjct: 1244 AKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAP 1283
>MET_OTOGA (Q2QLH6) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1382 Score = 41.2 bits (95), Expect = 0.003 Identities = 19/40 (47%), Positives = 31/40 (77%) Frame = -3 Query: 621 SRVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAP 502 +++ V + A E+ +++KFT KSDV+SFGVL+ E++T AP Sbjct: 1244 AKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAP 1283
>MET_MICMU (Q2QL89) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1382 Score = 41.2 bits (95), Expect = 0.003 Identities = 19/40 (47%), Positives = 31/40 (77%) Frame = -3 Query: 621 SRVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAP 502 +++ V + A E+ +++KFT KSDV+SFGVL+ E++T AP Sbjct: 1244 AKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAP 1283
>MET_CANFA (Q75ZY9) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1382 Score = 41.2 bits (95), Expect = 0.003 Identities = 19/40 (47%), Positives = 31/40 (77%) Frame = -3 Query: 621 SRVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAP 502 +++ V + A E+ +++KFT KSDV+SFGVL+ E++T AP Sbjct: 1244 AKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAP 1283
>OXSR1_PIG (Q863I2) Serine/threonine-protein kinase OSR1 (EC 2.7.11.1)| (Oxidative stress-responsive 1 protein) Length = 529 Score = 41.2 bits (95), Expect = 0.003 Identities = 30/109 (27%), Positives = 53/109 (48%), Gaps = 6/109 (5%) Frame = -3 Query: 603 YRAPETYES-RKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDVIDL-----PRWVHSVV 442 + APE E R + K+D++SFG+ +E+ TG AP V+ L P + + V Sbjct: 192 WMAPEVMEQVRGYDFKADIWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPSLETGV 251 Query: 441 REEWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIR 295 +++ L KY +++ + C + P++RPT AE++R Sbjct: 252 QDK-------EMLKKYGKSFRKMISL------CLQKDPEKRPTAAELLR 287
>FGR_HUMAN (P09769) Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2)| (P55-FGR) (C-FGR) Length = 529 Score = 41.2 bits (95), Expect = 0.003 Identities = 20/56 (35%), Positives = 34/56 (60%), Gaps = 1/56 (1%) Frame = -3 Query: 633 PINTSRVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVID 469 P S+ + + APE +FT KSDV+SFG+L+ E++T G+ P + +V++ Sbjct: 414 PCQGSKFPIKWTAPEAALFGRFTIKSDVWSFGILLTELITKGRIPYPGMNKREVLE 469
>KPCD_MOUSE (P28867) Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta)| Length = 674 Score = 41.2 bits (95), Expect = 0.003 Identities = 19/58 (32%), Positives = 32/58 (55%), Gaps = 8/58 (13%) Frame = -3 Query: 603 YRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDVID--------LPRWV 454 Y APE + K++ D +SFGVL+ EML G++P ++++ + PRW+ Sbjct: 512 YIAPEILQGLKYSFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDTPHYPRWI 569
>KPCD_CANFA (Q5PU49) Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta)| Length = 674 Score = 41.2 bits (95), Expect = 0.003 Identities = 19/58 (32%), Positives = 32/58 (55%), Gaps = 8/58 (13%) Frame = -3 Query: 603 YRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDVID--------LPRWV 454 Y APE + K++ D +SFGVL+ EML G++P ++++ + PRW+ Sbjct: 512 YIAPEILQGLKYSFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDTPHYPRWI 569
>EPHB3_HUMAN (P54753) Ephrin type-B receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor HEK-2) Length = 998 Score = 41.2 bits (95), Expect = 0.003 Identities = 22/80 (27%), Positives = 41/80 (51%), Gaps = 14/80 (17%) Frame = -3 Query: 618 RVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVI---------- 472 ++ + + APE RKFT SDV+S+G+++ E+++ G+ P +DVI Sbjct: 799 KIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAVEQDYRLP 858 Query: 471 ---DLPRWVHSVVREEWTAE 421 D P +H ++ + W + Sbjct: 859 PPMDCPTALHQLMLDCWVRD 878
>EPHB2_MOUSE (P54763) Ephrin type-B receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3) Length = 994 Score = 41.2 bits (95), Expect = 0.003 Identities = 22/77 (28%), Positives = 41/77 (53%), Gaps = 14/77 (18%) Frame = -3 Query: 618 RVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVI---------- 472 ++ + + APE + RKFT SDV+S+G+++ E+++ G+ P +DVI Sbjct: 795 KIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRLP 854 Query: 471 ---DLPRWVHSVVREEW 430 D P +H ++ + W Sbjct: 855 PPMDCPSALHQLMLDCW 871
>VGFR2_HUMAN (P35968) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Kinase insert domain receptor) (Protein-tyrosine kinase receptor Flk-1) (CD309 antigen) Length = 1356 Score = 41.2 bits (95), Expect = 0.003 Identities = 32/122 (26%), Positives = 59/122 (48%), Gaps = 1/122 (0%) Frame = -3 Query: 621 SRVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSV 445 +R+ + + APET R +T +SDV+SFGVL+ E+ + G +P + Sbjct: 1065 ARLPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASP--------------YPGVK 1110 Query: 444 VREEWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTA 265 + EE+ + + M+ + +M Q + C P +RPT +E++ + +L Q A Sbjct: 1111 IDEEFCRRLKEGTRMRAPDYTTP--EMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQANA 1168 Query: 264 SE 259 + Sbjct: 1169 QQ 1170
>STK39_MOUSE (Q9Z1W9) STE20/SPS1-related proline-alanine-rich protein kinase (EC| 2.7.11.1) (Ste-20-related kinase) (Serine/threonine-protein kinase 39) Length = 556 Score = 40.8 bits (94), Expect = 0.003 Identities = 31/106 (29%), Positives = 51/106 (48%), Gaps = 3/106 (2%) Frame = -3 Query: 603 YRAPETYES-RKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDVIDLPRWVHSVVREEWT 427 + APE E R + K+D++SFG+ +E+ TG AP V+ L ++ + T Sbjct: 250 WMAPEVMEQVRGYDFKADMWSFGITAIELATGAAPYHKYPPMKVLML-----TLQNDPPT 304 Query: 426 AE--VFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIR 295 E V D +MK + +L C + P +RPT AE+++ Sbjct: 305 LETGVEDKEMMKKYG-----KSFRKLLSLCLQKDPSKRPTAAELLK 345
>SRC_AVISS (P14084) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 567 Score = 40.8 bits (94), Expect = 0.003 Identities = 36/134 (26%), Positives = 57/134 (42%), Gaps = 3/134 (2%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVID-LPRWVHSVVRE 436 + + APE +FT KSDV+SFG+L+ E+ T G+ P +V+D + R Sbjct: 425 IKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPP 484 Query: 435 EWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQF-TASE 259 E + D+ + +E L F PT + M D ++ TA + Sbjct: 485 ECPESLHDLMCQCWRKDPEERPTFEYLQAFLEDYFTSTEPT---AVHMATDPGKYTTAHK 541 Query: 258 SRASSNENPRDSNP 217 SRA + N + P Sbjct: 542 SRARVSSNTAVARP 555
>IGF1R_XENLA (O73798) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (xIGF-1R) (xIGFR) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] Length = 1358 Score = 40.8 bits (94), Expect = 0.003 Identities = 33/110 (30%), Positives = 53/110 (48%), Gaps = 1/110 (0%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVVREE 433 V + +PE+ + FT SDV+SFGV++ E+ T + P Q E V+ R+V Sbjct: 1172 VRWMSPESLKDGVFTTNSDVWSFGVVLWEIATLAEQPYQGMSNEQVL---RFV------- 1221 Query: 432 WTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIED 283 + L K N D L +++++ C P RP+ E+I I+D Sbjct: 1222 ----MEGGLLEKPDNCPDMLFELMRM---CWQFNPKMRPSFLEIISSIKD 1264
>EPHA5_RAT (P54757) Ephrin type-A receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) Length = 1005 Score = 40.8 bits (94), Expect = 0.003 Identities = 28/114 (24%), Positives = 54/114 (47%), Gaps = 1/114 (0%) Frame = -3 Query: 618 RVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVV 442 ++ + + APE RKFT SDV+S+G+++ E+++ G+ P +DVI V Sbjct: 841 KIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVI-------KAV 893 Query: 441 REEWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDL 280 E + + + D + QL + C + + RP +++ M++ L Sbjct: 894 EEGY----------RLPSPMDCPAALYQLMLDCWQKDRNSRPKFDDIVNMLDKL 937
>M3K2_ARATH (Q9FZ36) Mitogen-activated protein kinase kinase kinase 2 (EC| 2.7.11.25) (Arabidospsis NPK1-related protein kinase 2) Length = 651 Score = 40.8 bits (94), Expect = 0.003 Identities = 33/130 (25%), Positives = 57/130 (43%), Gaps = 7/130 (5%) Frame = -3 Query: 603 YRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDVIDLPRWVHSVVREEWTA 424 + APE + +D++S G V+EM+TGKAP Q +E A Sbjct: 239 WMAPEVILQTGHSFSADIWSVGCTVIEMVTGKAPWSQQYKE-----------------IA 281 Query: 423 EVFDVALMKYH-----NIEDELVQMLQLAMACTSRFPDRRPTMAEVIR--MIEDLRQFTA 265 +F + K H NI + L + C + P+ RPT +E+++ + ++ +A Sbjct: 282 AIFHIGTTKSHPPIPDNISSDANDFL---LKCLQQEPNLRPTASELLKHPFVTGKQKESA 338 Query: 264 SESRASSNEN 235 S+ S +N Sbjct: 339 SKDLTSFMDN 348
>CSK_RAT (P32577) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| Length = 450 Score = 40.8 bits (94), Expect = 0.003 Identities = 20/53 (37%), Positives = 34/53 (64%), Gaps = 1/53 (1%) Frame = -3 Query: 627 NTSRVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVI 472 +T ++ V + APE +KF+ KSDV+SFG+L+ E+ + G+ P +DV+ Sbjct: 344 DTGKLPVKWTAPEALREKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVV 396
>CSK_MOUSE (P41241) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| (Protein-tyrosine kinase MPK-2) (p50CSK) Length = 450 Score = 40.8 bits (94), Expect = 0.003 Identities = 20/53 (37%), Positives = 34/53 (64%), Gaps = 1/53 (1%) Frame = -3 Query: 627 NTSRVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVI 472 +T ++ V + APE +KF+ KSDV+SFG+L+ E+ + G+ P +DV+ Sbjct: 344 DTGKLPVKWTAPEALREKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVV 396
>CSK_HUMAN (P41240) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| (Protein-tyrosine kinase CYL) Length = 450 Score = 40.8 bits (94), Expect = 0.003 Identities = 20/53 (37%), Positives = 34/53 (64%), Gaps = 1/53 (1%) Frame = -3 Query: 627 NTSRVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVI 472 +T ++ V + APE +KF+ KSDV+SFG+L+ E+ + G+ P +DV+ Sbjct: 344 DTGKLPVKWTAPEALREKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVV 396
>IPL1_ASHGO (Q755C4) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 367 Score = 40.8 bits (94), Expect = 0.003 Identities = 17/43 (39%), Positives = 26/43 (60%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQE 481 V Y +PE SR++ K DV++ GVL E+L G P + + +E Sbjct: 270 VDYLSPELIRSREYNEKVDVWALGVLTYELLVGSPPFEEESKE 312
>VGFR1_HUMAN (P17948) Vascular endothelial growth factor receptor 1 precursor (EC| 2.7.10.1) (VEGFR-1) (Vascular permeability factor receptor) (Tyrosine-protein kinase receptor FLT) (Flt-1) (Tyrosine-protein kinase FRT) (Fms-like tyrosine kinase 1) Length = 1338 Score = 40.8 bits (94), Expect = 0.003 Identities = 34/118 (28%), Positives = 57/118 (48%), Gaps = 2/118 (1%) Frame = -3 Query: 621 SRVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQS-QGQEDVIDLPRWVHS 448 +R+ + + APE+ + ++ KSDV+S+GVL+ E+ + G +P Q ED S Sbjct: 1059 TRLPLKWMAPESIFDKIYSTKSDVWSYGVLLWEIFSLGGSPYPGVQMDEDFC-------S 1111 Query: 447 VVREEWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQ 274 +RE M+ E ++ Q+ + C R P RP AE++ + DL Q Sbjct: 1112 RLREG----------MRMRAPEYSTPEIYQIMLDCWHRDPKERPRFAELVEKLGDLLQ 1159
>STK39_HUMAN (Q9UEW8) STE20/SPS1-related proline-alanine-rich protein kinase (EC| 2.7.11.1) (Ste-20-related kinase) (Serine/threonine-protein kinase 39) (DCHT) Length = 547 Score = 40.8 bits (94), Expect = 0.003 Identities = 31/106 (29%), Positives = 51/106 (48%), Gaps = 3/106 (2%) Frame = -3 Query: 603 YRAPETYES-RKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDVIDLPRWVHSVVREEWT 427 + APE E R + K+D++SFG+ +E+ TG AP V+ L ++ + T Sbjct: 240 WMAPEVMEQVRGYDFKADMWSFGITAIELATGAAPYHKYPPMKVLML-----TLQNDPPT 294 Query: 426 AE--VFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIR 295 E V D +MK + +L C + P +RPT AE+++ Sbjct: 295 LETGVEDKEMMKKYG-----KSFRKLLSLCLQKDPSKRPTAAELLK 335
>VGFR2_MOUSE (P35918) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Protein-tyrosine kinase receptor flk-1) (Fetal liver kinase 1) (Kinase NYK) Length = 1367 Score = 40.8 bits (94), Expect = 0.003 Identities = 31/122 (25%), Positives = 60/122 (49%), Gaps = 1/122 (0%) Frame = -3 Query: 621 SRVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSV 445 +R+ + + APET R +T +SDV+SFGVL+ E+ + G +P + Sbjct: 1063 ARLPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASP--------------YPGVK 1108 Query: 444 VREEWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTA 265 + EE+ + + M+ + +M Q + C P++RP+ +E++ + +L Q A Sbjct: 1109 IDEEFCRRLKEGTRMRAPDYTTP--EMYQTMLDCWHEDPNQRPSFSELVEHLGNLLQANA 1166 Query: 264 SE 259 + Sbjct: 1167 QQ 1168
>RON_MOUSE (Q62190) Macrophage-stimulating protein receptor precursor (EC| 2.7.10.1) (MSP receptor) (p185-Ron) (Stem cell-derived tyrosine kinase) (CDw136 antigen) [Contains: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating prote Length = 1378 Score = 40.8 bits (94), Expect = 0.003 Identities = 20/40 (50%), Positives = 30/40 (75%) Frame = -3 Query: 621 SRVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAP 502 +R+ V + A E+ ++ +FT KSDV+SFGVL+ E+LT AP Sbjct: 1224 ARLPVKWMALESLQTYRFTTKSDVWSFGVLLWELLTRGAP 1263
>STK39_RAT (O88506) STE20/SPS1-related proline-alanine-rich protein kinase (EC| 2.7.11.1) (Ste-20-related kinase) (Serine/threonine-protein kinase 39) (Pancreatic serine/threonine-protein kinase) (PS/TK) (PSTK1) Length = 553 Score = 40.8 bits (94), Expect = 0.003 Identities = 31/106 (29%), Positives = 51/106 (48%), Gaps = 3/106 (2%) Frame = -3 Query: 603 YRAPETYES-RKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDVIDLPRWVHSVVREEWT 427 + APE E R + K+D++SFG+ +E+ TG AP V+ L ++ + T Sbjct: 247 WMAPEVMEQVRGYDFKADMWSFGITAIELATGAAPYHKYPPMKVLML-----TLQNDPPT 301 Query: 426 AE--VFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIR 295 E V D +MK + +L C + P +RPT AE+++ Sbjct: 302 LETGVEDKEMMKKYG-----KSFRKLLSLCLQKDPSKRPTAAELLK 342
>NTRK3_SAIBB (Q5IS82) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) Length = 825 Score = 40.4 bits (93), Expect = 0.004 Identities = 33/116 (28%), Positives = 52/116 (44%), Gaps = 2/116 (1%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVVREE 433 + + PE+ RKFT +SDV+SFGV++ E+ T GK P +VI+ + R Sbjct: 720 IRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGKQPWFQLSNTEVIECITQGRVLERPR 779 Query: 432 -WTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFT 268 EV+DV L C R P +R + E+ +++ L + T Sbjct: 780 VCPKEVYDVML------------------GCWQREPQQRLNIKEIYKILHALGKAT 817
>NTRK3_PIG (P24786) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C) Length = 825 Score = 40.4 bits (93), Expect = 0.004 Identities = 33/116 (28%), Positives = 52/116 (44%), Gaps = 2/116 (1%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVVREE 433 + + PE+ RKFT +SDV+SFGV++ E+ T GK P +VI+ + R Sbjct: 720 IRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGKQPWFQLSNTEVIECITQGRVLERPR 779 Query: 432 -WTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFT 268 EV+DV L C R P +R + E+ +++ L + T Sbjct: 780 VCPKEVYDVML------------------GCWQREPQQRLNIKEIYKILHALGKAT 817
>NTRK3_PANTR (Q5IS37) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) Length = 825 Score = 40.4 bits (93), Expect = 0.004 Identities = 33/116 (28%), Positives = 52/116 (44%), Gaps = 2/116 (1%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVVREE 433 + + PE+ RKFT +SDV+SFGV++ E+ T GK P +VI+ + R Sbjct: 720 IRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGKQPWFQLSNTEVIECITQGRVLERPR 779 Query: 432 -WTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFT 268 EV+DV L C R P +R + E+ +++ L + T Sbjct: 780 VCPKEVYDVML------------------GCWQREPQQRLNIKEIYKILHALGKAT 817
>NTRK3_MACFA (Q5IFJ9) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) Length = 825 Score = 40.4 bits (93), Expect = 0.004 Identities = 33/116 (28%), Positives = 52/116 (44%), Gaps = 2/116 (1%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVVREE 433 + + PE+ RKFT +SDV+SFGV++ E+ T GK P +VI+ + R Sbjct: 720 IRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGKQPWFQLSNTEVIECITQGRVLERPR 779 Query: 432 -WTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFT 268 EV+DV L C R P +R + E+ +++ L + T Sbjct: 780 VCPKEVYDVML------------------GCWQREPQQRLNIKEIYKILHALGKAT 817
>NTRK3_HUMAN (Q16288) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C) Length = 839 Score = 40.4 bits (93), Expect = 0.004 Identities = 33/116 (28%), Positives = 52/116 (44%), Gaps = 2/116 (1%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVVREE 433 + + PE+ RKFT +SDV+SFGV++ E+ T GK P +VI+ + R Sbjct: 734 IRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGKQPWFQLSNTEVIECITQGRVLERPR 793 Query: 432 -WTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFT 268 EV+DV L C R P +R + E+ +++ L + T Sbjct: 794 VCPKEVYDVML------------------GCWQREPQQRLNIKEIYKILHALGKAT 831
>VGFR2_BRARE (Q8AXB3) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Receptor tyrosine kinase flk-1) Length = 1302 Score = 40.4 bits (93), Expect = 0.004 Identities = 31/122 (25%), Positives = 57/122 (46%), Gaps = 1/122 (0%) Frame = -3 Query: 621 SRVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSV 445 +R+ + + APE + +T +SDV+SFGVL+ E+ + G +P +H Sbjct: 1040 ARLPLKWMAPEAIFDKIYTTQSDVWSFGVLMWEIFSLGASPYPG------------LH-- 1085 Query: 444 VREEWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTA 265 + EE+ + + MK ++ Q + C P +RPT E++ + DL Q + Sbjct: 1086 IDEEFCCRLKEGTRMKAPEYSSS--EIYQTMLDCWHGEPSQRPTFTELVERLGDLLQASV 1143 Query: 264 SE 259 + Sbjct: 1144 QQ 1145
>NTRK3_RAT (Q03351) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C) Length = 864 Score = 40.4 bits (93), Expect = 0.004 Identities = 33/116 (28%), Positives = 52/116 (44%), Gaps = 2/116 (1%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVVREE 433 + + PE+ RKFT +SDV+SFGV++ E+ T GK P +VI+ + R Sbjct: 759 IRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGKQPWFQLSNTEVIECITQGRVLERPR 818 Query: 432 -WTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFT 268 EV+DV L C R P +R + E+ +++ L + T Sbjct: 819 VCPKEVYDVML------------------GCWQREPQQRLNIKEIYKILHALGKAT 856
>ITK_HUMAN (Q08881) Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2)| (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT) Length = 620 Score = 40.4 bits (93), Expect = 0.004 Identities = 24/114 (21%), Positives = 54/114 (47%), Gaps = 2/114 (1%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVVREE 433 V + +PE + +++ KSDV+SFGVL+ E+ + GK P +++ +V++ Sbjct: 522 VKWASPEVFSFSRYSSKSDVWSFGVLMWEVFSEGKIPYENRSNSEVVE------------ 569 Query: 432 WTAEVFDVAL-MKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQ 274 D++ + + + Q+ C P+ RP + ++R + ++ + Sbjct: 570 ------DISTGFRLYKPRLASTHVYQIMNHCWKERPEDRPAFSRLLRQLAEIAE 617
>SRC_RSVSE (P63185) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 40.4 bits (93), Expect = 0.004 Identities = 20/48 (41%), Positives = 30/48 (62%), Gaps = 1/48 (2%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVID 469 + + APE +FT KSDV+SFG+L+ E+ T G+ P G +V+D Sbjct: 425 IKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMGNGEVLD 472
>SRC_RSVSA (P00524) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 40.4 bits (93), Expect = 0.004 Identities = 20/48 (41%), Positives = 30/48 (62%), Gaps = 1/48 (2%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVID 469 + + APE +FT KSDV+SFG+L+ E+ T G+ P G +V+D Sbjct: 425 IKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMGNGEVLD 472
>SRC_AVISR (P00525) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 40.4 bits (93), Expect = 0.004 Identities = 20/48 (41%), Positives = 30/48 (62%), Gaps = 1/48 (2%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVID 469 + + APE +FT KSDV+SFG+L+ E+ T G+ P G +V+D Sbjct: 425 IKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMGNGEVLD 472
>LRRK1_MOUSE (Q3UHC2) Leucine-rich repeat serine/threonine-protein kinase 1 (EC| 2.7.11.1) Length = 2014 Score = 40.4 bits (93), Expect = 0.004 Identities = 25/109 (22%), Positives = 52/109 (47%), Gaps = 1/109 (0%) Frame = -3 Query: 606 GYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDVI-DLPRWVHSVVREEW 430 GY+APE + K D++S+G+++ E+L+G+ P Q ++ L + + V+ + Sbjct: 1429 GYQAPEIRPRIVYDEKVDMFSYGMVLYELLSGQRPALGHHQLQIVKKLSKGIRPVLGQP- 1487 Query: 429 TAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIED 283 +++H ++ L M C P++RP V+ ++D Sbjct: 1488 -------EEVQFHRLQ-------ALMMECWDTKPEKRPLALSVVSQMKD 1522
>SEA_AVIET (P23049) Tyrosine-protein kinase transforming protein SEA (EC| 2.7.10.2) Length = 370 Score = 40.4 bits (93), Expect = 0.004 Identities = 23/57 (40%), Positives = 39/57 (68%), Gaps = 1/57 (1%) Frame = -3 Query: 621 SRVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWV 454 +++ V + A E+ +++KFT KSDV+SFGVL+ E+LT G +P + D D+ R++ Sbjct: 225 AKLPVRWMALESLQTQKFTTKSDVWSFGVLMWELLTRGASPYP---EVDPYDMARYL 278
>GRK1_CAEBR (Q622Z7) G protein-coupled receptor kinase 1 (EC 2.7.11.16)| Length = 640 Score = 40.4 bits (93), Expect = 0.004 Identities = 18/51 (35%), Positives = 30/51 (58%) Frame = -3 Query: 633 PINTSRVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQE 481 PI VGY APE ++ ++T+ D + G L+ EM+ GKAP + + ++ Sbjct: 357 PIKGRVGTVGYMAPEIVKNERYTYGVDWWGVGCLIYEMIEGKAPFRQRKEK 407
>EPHA3_MOUSE (P29319) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ETK1) (MEK4) Length = 983 Score = 40.0 bits (92), Expect = 0.006 Identities = 17/50 (34%), Positives = 32/50 (64%), Gaps = 1/50 (2%) Frame = -3 Query: 618 RVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVI 472 ++ + + +PE RKFT SDV+S+G+++ E+++ G+ P +DVI Sbjct: 785 KIPIRWTSPEAMSYRKFTSASDVWSYGIVLWEVMSYGERPYSQMSNQDVI 834
>EPHA3_BRARE (O13146) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ZEK1) (EPH-like kinase 1) Length = 981 Score = 40.0 bits (92), Expect = 0.006 Identities = 18/50 (36%), Positives = 32/50 (64%), Gaps = 1/50 (2%) Frame = -3 Query: 618 RVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVI 472 ++ + + APE RKFT SDV+S+G+++ E+++ G+ P +DVI Sbjct: 790 KIPIRWTAPEAITYRKFTSASDVWSYGIVMWEVISYGERPYWEMSNQDVI 839
>ITK_MOUSE (Q03526) Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2)| (T-cell-specific kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK) Length = 625 Score = 40.0 bits (92), Expect = 0.006 Identities = 17/48 (35%), Positives = 33/48 (68%), Gaps = 1/48 (2%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVID 469 V + +PE + +++ KSDV+SFGVL+ E+ + GK P +++ +V++ Sbjct: 527 VKWASPEVFSFSRYSSKSDVWSFGVLMWEVFSEGKIPYENRSNSEVVE 574
>VGFR3_RAT (Q91ZT1) Vascular endothelial growth factor receptor 3 precursor (EC| 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4) Length = 1363 Score = 40.0 bits (92), Expect = 0.006 Identities = 28/118 (23%), Positives = 58/118 (49%), Gaps = 1/118 (0%) Frame = -3 Query: 624 TSRVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHS 448 ++R+ + + APE+ + +T +SDV+SFGVL+ E+ + G +P + Sbjct: 1073 SARLPLKWMAPESIFDKVYTTQSDVWSFGVLLWEIFSLGASP--------------YPGV 1118 Query: 447 VVREEWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQ 274 + EE+ + D M+ + ++ + +C S P RP ++++ ++ DL Q Sbjct: 1119 QINEEFCQRLKDGTRMRAPELATPAIR--HIMQSCWSGDPKARPAFSDLVEILGDLLQ 1174
>VGFR3_MOUSE (P35917) Vascular endothelial growth factor receptor 3 precursor (EC| 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4) Length = 1363 Score = 40.0 bits (92), Expect = 0.006 Identities = 28/118 (23%), Positives = 58/118 (49%), Gaps = 1/118 (0%) Frame = -3 Query: 624 TSRVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHS 448 ++R+ + + APE+ + +T +SDV+SFGVL+ E+ + G +P + Sbjct: 1073 SARLPLKWMAPESIFDKVYTTQSDVWSFGVLLWEIFSLGASP--------------YPGV 1118 Query: 447 VVREEWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQ 274 + EE+ + D M+ + ++ + +C S P RP ++++ ++ DL Q Sbjct: 1119 QINEEFCQRLKDGTRMRAPELATPAIR--HIMQSCWSGDPKARPAFSDLVEILGDLLQ 1174
>MET_HUMAN (P08581) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1390 Score = 40.0 bits (92), Expect = 0.006 Identities = 18/40 (45%), Positives = 31/40 (77%) Frame = -3 Query: 621 SRVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAP 502 +++ V + A E+ +++KFT KSDV+SFGV++ E++T AP Sbjct: 1243 AKLPVKWMALESLQTQKFTTKSDVWSFGVVLWELMTRGAP 1282
>NTRK3_CHICK (Q91044) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (Trk-C) Length = 827 Score = 40.0 bits (92), Expect = 0.006 Identities = 32/116 (27%), Positives = 52/116 (44%), Gaps = 2/116 (1%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVVREE 433 + + PE+ RKFT +SDV+SFGV++ E+ T GK P +VI+ + R Sbjct: 722 IRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGKQPWFQLSNTEVIECITQGRVLERPR 781 Query: 432 -WTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFT 268 EV+D+ L C R P +R + E+ +++ L + T Sbjct: 782 VCPKEVYDIML------------------GCWQREPQQRLNIKEIYKILHALGKAT 819
>M3K10_HUMAN (Q02779) Mitogen-activated protein kinase kinase kinase 10 (EC| 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST) Length = 954 Score = 40.0 bits (92), Expect = 0.006 Identities = 28/110 (25%), Positives = 46/110 (41%) Frame = -3 Query: 603 YRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDVIDLPRWVHSVVREEWTA 424 + APE F+ SDV+SFGVL+ E+LTG+ P + ID + V + T Sbjct: 269 WMAPEVIRLSLFSKSSDVWSFGVLLWELLTGEVPYRE------IDALAVAYGVAMNKLTL 322 Query: 423 EVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQ 274 + + + +E C P RP +++ +E + Q Sbjct: 323 PIPSTCPEPFARLLEE----------CWDPDPHGRPDFGSILKRLEVIEQ 362
>KS6A_CAEEL (Q21734) Putative ribosomal protein S6 kinase alpha (EC 2.7.11.1)| Length = 784 Score = 40.0 bits (92), Expect = 0.006 Identities = 19/46 (41%), Positives = 26/46 (56%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDVI 472 V Y APE R + +D +S GVL+ EMLTG P Q + + D + Sbjct: 268 VEYMAPEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTM 313 Score = 31.6 bits (70), Expect = 2.1 Identities = 17/43 (39%), Positives = 22/43 (51%) Frame = -3 Query: 597 APETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDVID 469 APE + + DV+S GVL+ MLTG P + G D D Sbjct: 619 APEVLRKQGYDRSCDVWSLGVLLHTMLTGCTPF-AMGPNDTPD 660
>EPHA2_HUMAN (P29317) Ephrin type-A receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) Length = 976 Score = 40.0 bits (92), Expect = 0.006 Identities = 28/114 (24%), Positives = 53/114 (46%), Gaps = 1/114 (0%) Frame = -3 Query: 618 RVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVV 442 ++ + + APE RKFT SDV+SFG+++ E++T G+ P +V+ + Sbjct: 778 KIPIRWTAPEAISYRKFTSASDVWSFGIVMWEVMTYGERPYWELSNHEVM-------KAI 830 Query: 441 REEWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDL 280 + + + D + QL M C + RRP A+++ +++ L Sbjct: 831 NDGF----------RLPTPMDCPSAIYQLMMQCWQQERARRPKFADIVSILDKL 874
>SRC_AVIST (P14085) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 556 Score = 40.0 bits (92), Expect = 0.006 Identities = 34/129 (26%), Positives = 50/129 (38%), Gaps = 2/129 (1%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVID-LPRWVHSVVRE 436 + + APE +FT KSDV+SFG+L+ E+ T G+ P +V+D + R Sbjct: 425 IKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPP 484 Query: 435 EWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTASES 256 E + D L C + P+ RPT + +ED A Sbjct: 485 ECPESLHD------------------LMCQCWRKDPEERPTFEYLQAFLEDYLGILAWTP 526 Query: 255 RASSNENPR 229 E PR Sbjct: 527 WEDKQEGPR 535
>KS6A5_CHICK (Q5F3L1) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1)| Length = 789 Score = 40.0 bits (92), Expect = 0.006 Identities = 17/48 (35%), Positives = 27/48 (56%) Frame = -3 Query: 633 PINTSRVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQ 490 P+ T + Y APE + + D++S GV++ ML+G+ P QSQ Sbjct: 568 PLKTPCFTLHYAAPELFNHNGYDESCDLWSLGVILYTMLSGQVPFQSQ 615
>ICL1_KLULA (Q6CWQ4) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 361 Score = 39.7 bits (91), Expect = 0.008 Identities = 16/43 (37%), Positives = 27/43 (62%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQE 481 + Y +PE +SR++ +K DV++ GVL E+L G P + +E Sbjct: 261 IDYLSPELIKSREYNNKVDVWALGVLTYELLVGSPPFEEDTKE 303
>IGF1R_BOVIN (Q05688) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] (F Length = 640 Score = 39.7 bits (91), Expect = 0.008 Identities = 31/111 (27%), Positives = 52/111 (46%), Gaps = 2/111 (1%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVVREE 433 V + +PE+ + FT SDV+SFGV++ E+ T + P Q E V+ Sbjct: 449 VRWMSPESLKDGVFTTHSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRF----------- 497 Query: 432 WTAEVFDVALM-KYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIED 283 V + L+ K N D L +++++ C P RP+ E+I ++D Sbjct: 498 ----VMEGGLLDKPDNCPDMLFELMRM---CWQYNPKMRPSFLEIISSVKD 541
>IRAK1_MOUSE (Q62406) Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1)| (IRAK-1) (IRAK) (Pelle-like protein kinase) (mPLK) Length = 710 Score = 39.7 bits (91), Expect = 0.008 Identities = 34/156 (21%), Positives = 65/156 (41%), Gaps = 24/156 (15%) Frame = -3 Query: 627 NTSRVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQ-----EDVID-- 469 +T R + Y E ++ + +D +SFGV+++E L G+ +++QG +D+I+ Sbjct: 382 STVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVILETLAGQRAVRTQGAKTKYLKDLIEDE 441 Query: 468 -----------LPRWVHSVVREEWTAEVFDVALMKYHNIEDEL------VQMLQLAMACT 340 P V + W A + K+ + + + QLA C Sbjct: 442 AEEAGVTLKSTQPTLWVGVATDAWAAPIAAQIYKKHLDSRPGPCPPQLGLALAQLACCCM 501 Query: 339 SRFPDRRPTMAEVIRMIEDLRQFTASESRASSNENP 232 R +RP M +V + +E L+ E + + +P Sbjct: 502 HRRAKKRPPMTQVYKRLEGLQAGPPWELEVAGHGSP 537
>TOPK_MOUSE (Q9JJ78) T-lymphokine-activated killer cell-originated protein| kinase (EC 2.7.12.2) (T-LAK cell-originated protein kinase) (PDZ-binding kinase) Length = 330 Score = 39.7 bits (91), Expect = 0.008 Identities = 25/100 (25%), Positives = 50/100 (50%), Gaps = 1/100 (1%) Frame = -3 Query: 582 ESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDVIDLPRWVHSVVREE-WTAEVFDVA 406 E+ T K+DV++FG+ + EM+T P + +DV + + S +E + A + Sbjct: 219 ENGIITDKADVFAFGLTLWEMMTLCIPHVNLPDDDVDEDATFDESDFDDEAYYAALGTRP 278 Query: 405 LMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIE 286 + ++D + ++L CT+ P RP+ A ++ +E Sbjct: 279 SINMEELDDSYQKAIELFCVCTNEDPKDRPSAAHIVEALE 318
>IGF1R_MOUSE (Q60751) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] Length = 1373 Score = 39.7 bits (91), Expect = 0.008 Identities = 32/111 (28%), Positives = 52/111 (46%), Gaps = 2/111 (1%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVVREE 433 V + +PE+ + FT SDV+SFGV++ E+ T + P Q E V+ Sbjct: 1178 VRWMSPESLKDGVFTTHSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRF----------- 1226 Query: 432 WTAEVFDVALM-KYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIED 283 V + L+ K N D L +++++ C P RP+ E+I I+D Sbjct: 1227 ----VMEGGLLDKPDNCPDMLFELMRM---CWQYNPKMRPSFLEIIGSIKD 1270
>M3K1_ARATH (O22040) Mitogen-activated protein kinase kinase kinase 1 (EC| 2.7.11.25) (Arabidospsis NPK1-related protein kinase 1) Length = 666 Score = 39.7 bits (91), Expect = 0.008 Identities = 29/105 (27%), Positives = 45/105 (42%), Gaps = 2/105 (1%) Frame = -3 Query: 603 YRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDVIDLPRWVHSVVREEWTA 424 + APE + +D++S G V+EM+TGKAP Q +E A Sbjct: 240 WMAPEVILQTGHSFSADIWSVGCTVIEMVTGKAPWSQQYKE-----------------VA 282 Query: 423 EVFDVALMKYH-NIEDEL-VQMLQLAMACTSRFPDRRPTMAEVIR 295 +F + K H I D L + C P+ RPT +E+++ Sbjct: 283 AIFFIGTTKSHPPIPDTLSSDAKDFLLKCLQEVPNLRPTASELLK 327
>IGF1R_RAT (P24062) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] Length = 1370 Score = 39.7 bits (91), Expect = 0.008 Identities = 32/111 (28%), Positives = 52/111 (46%), Gaps = 2/111 (1%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVVREE 433 V + +PE+ + FT SDV+SFGV++ E+ T + P Q E V+ Sbjct: 1177 VRWMSPESLKDGVFTTHSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRF----------- 1225 Query: 432 WTAEVFDVALM-KYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIED 283 V + L+ K N D L +++++ C P RP+ E+I I+D Sbjct: 1226 ----VMEGGLLDKPDNCPDMLFELMRM---CWQYNPKMRPSFLEIIGSIKD 1269
>EPHA2_MOUSE (Q03145) Ephrin type-A receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2) Length = 977 Score = 39.7 bits (91), Expect = 0.008 Identities = 27/114 (23%), Positives = 53/114 (46%), Gaps = 1/114 (0%) Frame = -3 Query: 618 RVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVV 442 ++ + + APE RKFT SDV+S+G+++ E++T G+ P +V+ + Sbjct: 779 KIPIRWTAPEAISYRKFTSASDVWSYGIVMWEVMTYGERPYWELSNHEVM-------KAI 831 Query: 441 REEWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDL 280 + + + D + QL M C + RRP A+++ +++ L Sbjct: 832 NDGF----------RLPTPMDCPSAIYQLMMQCWQQERSRRPKFADIVSILDKL 875
>GRK6_RAT (P97711) G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK6) Length = 576 Score = 39.7 bits (91), Expect = 0.008 Identities = 19/61 (31%), Positives = 35/61 (57%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDVIDLPRWVHSVVREEW 430 VGY APE ++ ++T D ++ G L+ EM+ G++P Q + ++ + + V EE+ Sbjct: 349 VGYMAPEVVKNERYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVAEEY 408 Query: 429 T 427 T Sbjct: 409 T 409
>SRC_AVIS2 (P15054) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 586 Score = 39.3 bits (90), Expect = 0.010 Identities = 33/119 (27%), Positives = 51/119 (42%), Gaps = 2/119 (1%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVID-LPRWVHSVVRE 436 + + APE +FT KSDV+SFG+L+ E+ T G+ P +V+D + R Sbjct: 425 IKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPP 484 Query: 435 EWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTASE 259 E + D L C + P+ RPT + +ED FT++E Sbjct: 485 ECPESLHD------------------LMCQCWRKDPEERPTFEYLQAFLED--YFTSTE 523
>GRK6_MOUSE (O70293) G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK6) Length = 576 Score = 39.3 bits (90), Expect = 0.010 Identities = 19/61 (31%), Positives = 34/61 (55%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDVIDLPRWVHSVVREEW 430 VGY APE + ++T D ++ G L+ EM+ G++P Q + ++ + + V EE+ Sbjct: 349 VGYMAPEVVRNERYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVAEEY 408 Query: 429 T 427 T Sbjct: 409 T 409
>VGFR1_MOUSE (P35969) Vascular endothelial growth factor receptor 1 precursor (EC| 2.7.10.1) (VEGFR-1) (Tyrosine-protein kinase receptor FLT) (FLT-1) (Embryonic receptor kinase 2) Length = 1333 Score = 39.3 bits (90), Expect = 0.010 Identities = 32/118 (27%), Positives = 57/118 (48%), Gaps = 2/118 (1%) Frame = -3 Query: 621 SRVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQS-QGQEDVIDLPRWVHS 448 +R+ + + APE+ + ++ KSDV+S+GVL+ E+ + G +P Q ED S Sbjct: 1059 TRLPLKWMAPESIFDKVYSTKSDVWSYGVLLWEIFSLGGSPYPGVQMDEDFC-------S 1111 Query: 447 VVREEWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQ 274 ++E M+ E ++ Q+ + C + P RP AE++ + DL Q Sbjct: 1112 RLKEG----------MRMRTPEYATPEIYQIMLDCWHKDPKERPRFAELVEKLGDLLQ 1159
>M3K7_DROME (Q9V3Q6) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (TGF-beta-activated kinase 1) (dTAK1) Length = 678 Score = 39.3 bits (90), Expect = 0.010 Identities = 26/125 (20%), Positives = 58/125 (46%), Gaps = 1/125 (0%) Frame = -3 Query: 630 INTSRVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLTGKAPLQSQGQEDVIDLPRWVH 451 + +R + APE +E K+T K D++S+ +++ E+L+ K P + + Sbjct: 170 MTNNRGSAAWMAPEVFEGSKYTEKCDIFSWAIVLWEVLSRKQPFKGIDN---------AY 220 Query: 450 SVVREEWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDL-RQ 274 ++ + + E + IED L AC P+ RP+M ++ ++ ++ + Sbjct: 221 TIQWKIYKGERPPLLTTCPKRIED-------LMTACWKTVPEDRPSMQYIVGVMHEIVKD 273 Query: 273 FTASE 259 +T ++ Sbjct: 274 YTGAD 278
>VGFR1_RAT (P53767) Vascular endothelial growth factor receptor 1 precursor (EC| 2.7.10.1) (VEGFR-1) (Tyrosine-protein kinase receptor FLT) (FLT-1) Length = 1336 Score = 39.3 bits (90), Expect = 0.010 Identities = 32/118 (27%), Positives = 57/118 (48%), Gaps = 2/118 (1%) Frame = -3 Query: 621 SRVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQS-QGQEDVIDLPRWVHS 448 +R+ + + APE+ + ++ KSDV+S+GVL+ E+ + G +P Q ED S Sbjct: 1059 TRLPLKWMAPESIFDKVYSTKSDVWSYGVLLWEIFSLGGSPYPGVQMDEDFC-------S 1111 Query: 447 VVREEWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQ 274 ++E M+ E ++ Q+ + C + P RP AE++ + DL Q Sbjct: 1112 RLKEG----------MRMRTPEYATPEIYQIMLDCWHKDPKERPRFAELVEKLGDLLQ 1159
>EPHB4_MOUSE (P54761) Ephrin type-B receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor MDK-2) (Developmental kinase 2) (Tyrosine kinase MYK-1) Length = 987 Score = 39.3 bits (90), Expect = 0.010 Identities = 21/77 (27%), Positives = 39/77 (50%), Gaps = 14/77 (18%) Frame = -3 Query: 618 RVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVI---------- 472 ++ + + APE RKFT SD +S+G+++ E+++ G+ P +DVI Sbjct: 781 KISIRWTAPEAIAFRKFTSASDAWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLP 840 Query: 471 ---DLPRWVHSVVREEW 430 D P +H ++ + W Sbjct: 841 PPPDCPTSLHQLMLDCW 857
>EPHB4_HUMAN (P54760) Ephrin type-B receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor HTK) Length = 987 Score = 39.3 bits (90), Expect = 0.010 Identities = 21/77 (27%), Positives = 39/77 (50%), Gaps = 14/77 (18%) Frame = -3 Query: 618 RVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVI---------- 472 ++ + + APE RKFT SD +S+G+++ E+++ G+ P +DVI Sbjct: 781 KIPIRWTAPEAIAFRKFTSASDAWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLP 840 Query: 471 ---DLPRWVHSVVREEW 430 D P +H ++ + W Sbjct: 841 PPPDCPTSLHQLMLDCW 857
>VAB1_CAEEL (O61460) Ephrin receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein| kinase Eph receptor) (Variable abnormal protein 1) Length = 1122 Score = 39.3 bits (90), Expect = 0.010 Identities = 21/53 (39%), Positives = 31/53 (58%), Gaps = 1/53 (1%) Frame = -3 Query: 627 NTSRVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVI 472 N ++ V + APE RKFT SDV+SFGV++ E+ + G+ P + VI Sbjct: 888 NGGKIPVRWTAPEAITHRKFTPSSDVWSFGVVIWEVCSFGERPYWDWTNQKVI 940
>FGR_MOUSE (P14234) Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2)| (P55-FGR) (C-FGR) Length = 517 Score = 39.3 bits (90), Expect = 0.010 Identities = 19/56 (33%), Positives = 33/56 (58%), Gaps = 1/56 (1%) Frame = -3 Query: 633 PINTSRVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVID 469 P ++ + + APE +FT KSDV+SFG+L+ E++T G+ P +V++ Sbjct: 402 PQQGTKFPIKWTAPEAALFGRFTVKSDVWSFGILLTELITKGRVPYPGMNNREVLE 457
>EPB1A_XENLA (Q91571) Ephrin type-B receptor 1-A precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor XEK) Length = 985 Score = 39.3 bits (90), Expect = 0.010 Identities = 28/120 (23%), Positives = 58/120 (48%), Gaps = 1/120 (0%) Frame = -3 Query: 618 RVVVGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVIDLPRWVHSVV 442 ++ V + A E RKFT SDV+S+G+++ E+++ G+ P + +DVI + + Sbjct: 786 KIPVRWTAQEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWTMSNQDVI-------NAI 838 Query: 441 REEWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTAS 262 +++ + D + QL + C + + RP +AE++ + + + AS Sbjct: 839 EQDY----------RLPPPMDCPAALHQLMLDCWQKDRNSRPRLAEIVNTLRPMIRNPAS 888
>BLK_HUMAN (P51451) Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte| kinase) (p55-BLK) Length = 504 Score = 39.3 bits (90), Expect = 0.010 Identities = 33/119 (27%), Positives = 54/119 (45%), Gaps = 2/119 (1%) Frame = -3 Query: 609 VGYRAPETYESRKFTHKSDVYSFGVLVMEMLT-GKAPLQSQGQEDVI-DLPRWVHSVVRE 436 + + APE FT K+DV+SFGVL+ME++T G+ P +VI +L R + Sbjct: 398 IKWTAPEAIHFGVFTIKADVWSFGVLLMEVVTYGRVPYPGMSNPEVIRNLERGYRMPRPD 457 Query: 435 EWTAEVFDVALMKYHNIEDELVQMLQLAMACTSRFPDRRPTMAEVIRMIEDLRQFTASE 259 E++ + + C P+ RPT + ++ED +TA+E Sbjct: 458 TCPPELYRGVIAE-----------------CWRSRPEERPTFEFLQSVLEDF--YTATE 497 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 103,634,088 Number of Sequences: 219361 Number of extensions: 2524399 Number of successful extensions: 9645 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 8868 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 9565 length of database: 80,573,946 effective HSP length: 107 effective length of database: 57,102,319 effective search space used: 5938641176 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
