ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | rbags18f19 |
|---|---|
| Clone Library Name | barley_pub |
>PH1_ARATH (Q9ST43) Pleckstrin homology domain-containing protein 1 (AtPH1)| Length = 145 Score = 147 bits (372), Expect = 2e-35 Identities = 69/98 (70%), Positives = 82/98 (83%), Gaps = 2/98 (2%) Frame = -1 Query: 586 RRWFVLKQGKLFWFKDSTVT--RASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPGET 413 RRWFVLK+GKL WFKD R S PRGVI+V CLTVKGAEDV+N+ FAFELS+ T Sbjct: 45 RRWFVLKRGKLLWFKDQAAAGIRGSTPRGVISVGDCLTVKGAEDVVNKPFAFELSSGSYT 104 Query: 412 MYFVADSDKEKEDWINSIGRSIVQHSRSMTDDEIVDYD 299 M+F+AD++KEKE+WINSIGRSIVQHSRS+TD E++DYD Sbjct: 105 MFFIADNEKEKEEWINSIGRSIVQHSRSVTDSEVLDYD 142
>CENB2_HUMAN (Q15057) Centaurin-beta 2 (Cnt-b2)| Length = 778 Score = 49.7 bits (117), Expect = 6e-06 Identities = 33/106 (31%), Positives = 52/106 (49%), Gaps = 3/106 (2%) Frame = -1 Query: 586 RRWFVLKQGKLFW---FKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPGE 416 RRWF ++ +L + FKD+ P V+ TVK ED+ R+F FE+ +P + Sbjct: 286 RRWFSIQNNQLVYQKKFKDN-------PTVVVEDLRLCTVKHCEDI-ERRFCFEVVSPTK 337 Query: 415 TMYFVADSDKEKEDWINSIGRSIVQHSRSMTDDEIVDYDSGHPATG 278 + ADS+K ++ WI ++ SI R D+ P+TG Sbjct: 338 SCMLQADSEKLRQAWIKAVQTSIATAYREKGDESEKLDKKSSPSTG 383
>PKHA5_HUMAN (Q9HAU0) Pleckstrin homology domain-containing family A member 5| (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2) Length = 1116 Score = 46.2 bits (108), Expect = 7e-05 Identities = 24/77 (31%), Positives = 43/77 (55%), Gaps = 1/77 (1%) Frame = -1 Query: 586 RRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPG-ETM 410 +RWFVL LF+++D + ++ + + + +ED +NRK+AF+ + P T Sbjct: 189 KRWFVLSDLCLFYYRDEK--EEGILGSILLPSFQIALLTSEDHINRKYAFKAAHPNMRTY 246 Query: 409 YFVADSDKEKEDWINSI 359 YF D+ KE E W+ ++ Sbjct: 247 YFCTDTGKEMELWMKAM 263
>PLEK2_MOUSE (Q9WV52) Pleckstrin-2| Length = 353 Score = 43.1 bits (100), Expect = 6e-04 Identities = 25/80 (31%), Positives = 39/80 (48%), Gaps = 1/80 (1%) Frame = -1 Query: 583 RWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPGETMYF 404 RWF+L+Q L ++K R + P+G I + C + NR +L T T YF Sbjct: 24 RWFILRQNTLLYYKLEGGRRVTPPKGRIVLDGCTITCPCLEYENRPLLIKLKTRTSTEYF 83 Query: 403 V-ADSDKEKEDWINSIGRSI 347 + A S +E++ W I +I Sbjct: 84 LEACSREERDSWAFEITGAI 103
>KRAC_DICDI (P54644) RAC-family serine/threonine-protein kinase homolog (EC| 2.7.11.1) Length = 444 Score = 43.1 bits (100), Expect = 6e-04 Identities = 24/73 (32%), Positives = 40/73 (54%) Frame = -1 Query: 586 RRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPGETMY 407 +RWF+LK G L ++K VP GVI + + +K + D R FE+ TP T + Sbjct: 24 KRWFILKGGDLSYYKTKGEL---VPLGVIHLNTSGHIKNS-DRKKRVNGFEVQTPSRTYF 79 Query: 406 FVADSDKEKEDWI 368 +++++E+ WI Sbjct: 80 LCSETEEERAKWI 92
>PKHA2_BOVIN (Q3ZBA3) Pleckstrin homology domain-containing family A member 2| Length = 425 Score = 43.1 bits (100), Expect = 6e-04 Identities = 30/94 (31%), Positives = 42/94 (44%), Gaps = 6/94 (6%) Frame = -1 Query: 586 RRWFVLKQGKLFWFK---DSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPGE 416 RR+F L + +FK D R + V+ CL G D+L R FE+ T Sbjct: 217 RRFFALDDFTICYFKCEQDREPLRTIFLKDVLKTHECLVKSG--DLLMRDNLFEIITSSR 274 Query: 415 TMYFVADSDKEKEDWINSIGRSIVQ---HSRSMT 323 T Y ADS ++ WI IG ++ H R M+ Sbjct: 275 TFYVQADSPEDMHSWIKEIGAAVQALKCHPREMS 308
>PKHA2_HUMAN (Q9HB19) Pleckstrin homology domain-containing family A member 2| (Tandem PH domain-containing protein 2) (TAPP-2) Length = 425 Score = 42.7 bits (99), Expect = 8e-04 Identities = 27/83 (32%), Positives = 38/83 (45%), Gaps = 3/83 (3%) Frame = -1 Query: 586 RRWFVLKQGKLFWFK---DSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPGE 416 RR+F L + +FK D R + V+ CL G D+L R FE+ T Sbjct: 217 RRFFALDDFTICYFKCEQDREPLRTIFLKDVLKTHECLVKSG--DLLMRDNLFEIITSSR 274 Query: 415 TMYFVADSDKEKEDWINSIGRSI 347 T Y ADS ++ WI IG ++ Sbjct: 275 TFYVQADSPEDMHSWIKEIGAAV 297
>PKHA6_HUMAN (Q9Y2H5) Pleckstrin homology domain-containing family A member 6| (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3) Length = 1048 Score = 42.7 bits (99), Expect = 8e-04 Identities = 31/114 (27%), Positives = 50/114 (43%), Gaps = 15/114 (13%) Frame = -1 Query: 586 RRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPG-ETM 410 +RWFVL LF++KD S+ + ++ + D ++RK F+ G T Sbjct: 79 KRWFVLVDRCLFYYKDE--KEESILGSIPLLSFRVAAVQPSDNISRKHTFKAEHAGVRTY 136 Query: 409 YFVADSDKEKEDWINSIGRS--------------IVQHSRSMTDDEIVDYDSGH 290 +F A+S +E+E WI ++G + V+HS D E V H Sbjct: 137 FFSAESPEEQEAWIQAMGEAARVQIPPAQKSVPQAVRHSHEKPDSENVPPSKHH 190
>PKHA2_MOUSE (Q9ERS5) Pleckstrin homology domain-containing family A member 2| (Tandem PH domain-containing protein 2) (TAPP-2) (PH domain-containing adaptor PHAD47) Length = 425 Score = 42.4 bits (98), Expect = 0.001 Identities = 27/83 (32%), Positives = 38/83 (45%), Gaps = 3/83 (3%) Frame = -1 Query: 586 RRWFVLKQGKLFWFK---DSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPGE 416 RR+F L + +FK D R + V+ CL G D+L R FE+ T Sbjct: 217 RRFFALDDFTICYFKCEQDREPLRTIPLKDVLKTHECLVKSG--DLLMRDNLFEIITTSR 274 Query: 415 TMYFVADSDKEKEDWINSIGRSI 347 T Y ADS ++ WI IG ++ Sbjct: 275 TFYVQADSPEDMHSWIEGIGAAV 297
>PLEK2_HUMAN (Q9NYT0) Pleckstrin-2| Length = 353 Score = 42.0 bits (97), Expect = 0.001 Identities = 25/80 (31%), Positives = 39/80 (48%), Gaps = 1/80 (1%) Frame = -1 Query: 583 RWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPGETMYF 404 RWF+L+Q L ++K R + P+G I + C + NR +L T T YF Sbjct: 24 RWFILRQNTLVYYKLEGGRRVTPPKGRILLDGCTITCPCLEYENRPLLIKLKTQTSTEYF 83 Query: 403 V-ADSDKEKEDWINSIGRSI 347 + A S +E++ W I +I Sbjct: 84 LEACSREERDAWAFEITGAI 103
>PKHA6_MOUSE (Q7TQG1) Pleckstrin homology domain-containing family A member 6| (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3) Length = 1173 Score = 42.0 bits (97), Expect = 0.001 Identities = 24/80 (30%), Positives = 43/80 (53%), Gaps = 1/80 (1%) Frame = -1 Query: 586 RRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPG-ETM 410 +RWFVL LF++KD + S+ + ++ + D ++RK F+ G T Sbjct: 79 KRWFVLVDRCLFYYKDE--KQESILGSIPLLSFRVAAVQPSDNISRKHTFKAEHAGVRTY 136 Query: 409 YFVADSDKEKEDWINSIGRS 350 +F A+S +E+E WI ++G + Sbjct: 137 FFSAESPEEQEAWIQAMGEA 156
>PKHA4_HUMAN (Q9H4M7) Pleckstrin homology domain-containing family A member 4| (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1) Length = 779 Score = 42.0 bits (97), Expect = 0.001 Identities = 30/91 (32%), Positives = 44/91 (48%), Gaps = 1/91 (1%) Frame = -1 Query: 586 RRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPG-ETM 410 RRWFVL LF++KDS SV V+ + + G R+F F PG T Sbjct: 74 RRWFVLSGHCLFYYKDS--REESVLGSVLLPSYNIRPDGPGAPRGRRFTFTAEHPGMRTY 131 Query: 409 YFVADSDKEKEDWINSIGRSIVQHSRSMTDD 317 AD+ ++ W+ ++GR+ SR+ DD Sbjct: 132 VLAADTLEDLRGWLRALGRA----SRAEGDD 158
>CENB5_HUMAN (Q96P50) Centaurin-beta 5 (Cnt-b5)| Length = 759 Score = 41.6 bits (96), Expect = 0.002 Identities = 26/92 (28%), Positives = 45/92 (48%), Gaps = 3/92 (3%) Frame = -1 Query: 586 RRWFVLKQGKLFW---FKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPGE 416 RRWF ++ +L + KD+ V+ +VK ED+ R+F FE+ +P + Sbjct: 246 RRWFSIQNSQLVYQKKLKDALTV-------VVDDLRLCSVKPCEDI-ERRFCFEVLSPTK 297 Query: 415 TMYFVADSDKEKEDWINSIGRSIVQHSRSMTD 320 + ADS+K ++ W+ ++ SI R D Sbjct: 298 SCMLQADSEKLRQAWVQAVQASIASAYRESPD 329
>PKHA4_MOUSE (Q8VC98) Pleckstrin homology domain-containing family A member 4| (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1) Length = 588 Score = 41.2 bits (95), Expect = 0.002 Identities = 26/80 (32%), Positives = 39/80 (48%), Gaps = 1/80 (1%) Frame = -1 Query: 586 RRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPG-ETM 410 RRWFVL LF++KDS SV V+ + + G R+F F PG T Sbjct: 74 RRWFVLSGHCLFYYKDS--REESVLGSVLLPSYSVRPDGPGAPRGRRFTFTAEHPGMRTY 131 Query: 409 YFVADSDKEKEDWINSIGRS 350 AD+ ++ W+ ++GR+ Sbjct: 132 VLAADTLEDLRGWLRALGRA 151
>Y34F_DROME (Q9W5D0) Hypothetical protein CG12467 in chromosome 1| Length = 1561 Score = 41.2 bits (95), Expect = 0.002 Identities = 26/74 (35%), Positives = 34/74 (45%), Gaps = 1/74 (1%) Frame = -1 Query: 586 RRWFVLKQGKL-FWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPGETM 410 +RWFVLK G L +W V R P+G I + + AE FE+ T + Sbjct: 669 KRWFVLKNGSLNYWKSQHDVQRK--PQGQIQLDEVCRINRAEGAST----FEIDTGKKVY 722 Query: 409 YFVADSDKEKEDWI 368 Y ADS +DWI Sbjct: 723 YLTADSHATMDDWI 736
>TARA_MOUSE (Q99KW3) TRIO and F-actin-binding protein (Protein Tara)| (Trio-associated repeat on actin) Length = 2014 Score = 40.0 bits (92), Expect = 0.005 Identities = 21/80 (26%), Positives = 38/80 (47%) Frame = -1 Query: 586 RRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPGETMY 407 + WFVL L +++DST A G I + SC V E + R + F++ T Sbjct: 1458 KHWFVLTDSSLKYYRDSTAEEADELDGEIDLRSCTDV--TEYAVQRNYGFQIHTKDAVYT 1515 Query: 406 FVADSDKEKEDWINSIGRSI 347 A + + +WI ++ +++ Sbjct: 1516 LSAMTSGIRRNWIEALRKTV 1535
>VILD_DICDI (Q8WQ85) Villidin| Length = 1704 Score = 40.0 bits (92), Expect = 0.005 Identities = 20/102 (19%), Positives = 55/102 (53%), Gaps = 10/102 (9%) Frame = -1 Query: 583 RWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLN-RKFAFELSTPGETMY 407 +W+V+ +G L+ +K+ ++ + P I + ++ +++ + F+F+LSTP ++ Sbjct: 749 KWYVVSEGMLYSYKNKSLKQLD-PLETIHLEKAISAHKTKEIFTIQGFSFQLSTPNRIIH 807 Query: 406 FVADSDKEKEDWINSIGRSIVQH---------SRSMTDDEIV 308 +A + +E+ W++ + +++ +R+ T DE++ Sbjct: 808 LLAKTKEERGSWLSVLRQNLKSSGETKPKSVLTRASTMDELI 849
>TARA_HUMAN (Q9H2D6) TRIO and F-actin-binding protein (Protein Tara)| (Trio-associated repeat on actin) Length = 2365 Score = 40.0 bits (92), Expect = 0.005 Identities = 21/80 (26%), Positives = 38/80 (47%) Frame = -1 Query: 586 RRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPGETMY 407 + WFVL L +++DST A G I + SC V E + R + F++ T Sbjct: 1809 KHWFVLTDSSLKYYRDSTAEEADELDGEIDLRSCTDV--TEYAVQRNYGFQIHTKDAVYT 1866 Query: 406 FVADSDKEKEDWINSIGRSI 347 A + + +WI ++ +++ Sbjct: 1867 LSAMTSGIRRNWIEALRKTV 1886
>PKHA4_RAT (P60669) Pleckstrin homology domain-containing family A member 4| (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1) Length = 779 Score = 40.0 bits (92), Expect = 0.005 Identities = 25/80 (31%), Positives = 39/80 (48%), Gaps = 1/80 (1%) Frame = -1 Query: 586 RRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPG-ETM 410 RRWFVL LF++KDS SV V+ + + G R+F F PG T Sbjct: 74 RRWFVLSGHCLFYYKDS--REESVLGSVLLPSYSVRPDGPGAPRGRRFTFTAEHPGMRTY 131 Query: 409 YFVADSDKEKEDWINSIGRS 350 AD+ ++ W+ ++G++ Sbjct: 132 VLAADTLEDLRGWLRALGKA 151
>CEND1_HUMAN (Q8WZ64) Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin| repeat and pleckstrin homology domain-containing protein 2) (PARX protein) Length = 1704 Score = 39.7 bits (91), Expect = 0.006 Identities = 17/48 (35%), Positives = 33/48 (68%) Frame = -1 Query: 448 KFAFELSTPGETMYFVADSDKEKEDWINSIGRSIVQHSRSMTDDEIVD 305 K +FE+ TP + F A+++KEK+DWI ++ +SI + +++D E+ + Sbjct: 645 KQSFEIITPYRSFSFTAETEKEKQDWIEAVQQSIAE---TLSDYEVAE 689 Score = 29.6 bits (65), Expect = 6.7 Identities = 22/84 (26%), Positives = 42/84 (50%), Gaps = 2/84 (2%) Frame = -1 Query: 583 RWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPGET--M 410 R+FVL+ G LF +KD ++S + +++S +G + + ++ L+ E Sbjct: 1459 RYFVLRDGFLFLYKD---VKSSKHDKMFSLSSMKFYRGVKKKMKPPTSWGLTAYSEKHHW 1515 Query: 409 YFVADSDKEKEDWINSIGRSIVQH 338 + DS + + +W+ SI I QH Sbjct: 1516 HLCCDSSQTQTEWMTSI--FIAQH 1537
>CEND1_MOUSE (Q8BZ05) Centaurin-delta 1 (Cnt-d1)| Length = 1703 Score = 39.7 bits (91), Expect = 0.006 Identities = 17/48 (35%), Positives = 33/48 (68%) Frame = -1 Query: 448 KFAFELSTPGETMYFVADSDKEKEDWINSIGRSIVQHSRSMTDDEIVD 305 K +FE+ TP + F ADS++EK++WI ++ +SI + +++D E+ + Sbjct: 643 KQSFEIITPYRSFSFTADSEREKQEWIEAVQQSIAE---TLSDYEVAE 687
>DOCK9_HUMAN (Q9BZ29) Dedicator of cytokinesis protein 9 (Cdc42 guanine| nucleotide exchange factor zizimin 1) Length = 2069 Score = 39.7 bits (91), Expect = 0.006 Identities = 29/84 (34%), Positives = 46/84 (54%), Gaps = 6/84 (7%) Frame = -1 Query: 586 RRWFVLKQ-----GKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTP 422 RR+F L Q L ++KD +++ P+G I + SC+ V V R+FAFEL Sbjct: 199 RRFFHLIQLGDGSYNLNFYKDEKISKE--PKGSIFLDSCMGVVQNNKV--RRFAFELKMQ 254 Query: 421 GETMYFVA-DSDKEKEDWINSIGR 353 ++ Y +A DS+ E E+WI + + Sbjct: 255 DKSSYLLAADSEVEMEEWITILNK 278
>MYO10_HUMAN (Q9HD67) Myosin-10 (Myosin X)| Length = 2058 Score = 38.9 bits (89), Expect = 0.011 Identities = 23/92 (25%), Positives = 44/92 (47%) Frame = -1 Query: 586 RRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPGETMY 407 +RWFVL+Q KL +F++ + + +G + V T K D ++ ++ T + Sbjct: 1236 KRWFVLRQSKLMYFENDSEEKL---KGTVEVR---TAKEIIDNTTKENGIDIIMADRTFH 1289 Query: 406 FVADSDKEKEDWINSIGRSIVQHSRSMTDDEI 311 +A+S ++ W S++ + TD EI Sbjct: 1290 LIAESPEDASQWF-----SVLSQVHASTDQEI 1316
>DOCK9_MOUSE (Q8BIK4) Dedicator of cytokinesis protein 9 (Cdc42 guanine| nucleotide exchange factor zizimin 1) Length = 2055 Score = 38.9 bits (89), Expect = 0.011 Identities = 28/84 (33%), Positives = 46/84 (54%), Gaps = 6/84 (7%) Frame = -1 Query: 586 RRWFVLKQ-----GKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTP 422 RR+F L Q L ++KD +++ P+G I + SC+ V V R+FAFEL Sbjct: 210 RRFFHLIQLGDGSYNLNFYKDEKISKE--PKGSIFLDSCMGVIQNNRV--RRFAFELKMQ 265 Query: 421 GETMYFVA-DSDKEKEDWINSIGR 353 ++ Y +A DS+ E E+W+ + + Sbjct: 266 DKSSYLLAADSEAEMEEWVTVLNK 289
>PKHA1_MOUSE (Q8BUL6) Pleckstrin homology domain-containing family A member 1| (Tandem PH domain-containing protein 1) (TAPP-1) Length = 383 Score = 38.1 bits (87), Expect = 0.019 Identities = 25/83 (30%), Positives = 39/83 (46%), Gaps = 2/83 (2%) Frame = -1 Query: 586 RRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAE--DVLNRKFAFELSTPGET 413 RR+F L + + +FK P VI + V+ + D++ R FE+ T T Sbjct: 210 RRYFQLDENTIGYFKSELEKE---PLRVIPLKEVHKVQECKQSDIMMRDNLFEIVTTSRT 266 Query: 412 MYFVADSDKEKEDWINSIGRSIV 344 Y ADS +E WI ++ +IV Sbjct: 267 FYVQADSPEEMHSWIKAVSGAIV 289
>PKHA1_HUMAN (Q9HB21) Pleckstrin homology domain-containing family A member 1| (Tandem PH domain-containing protein 1) (TAPP-1) Length = 404 Score = 38.1 bits (87), Expect = 0.019 Identities = 25/83 (30%), Positives = 39/83 (46%), Gaps = 2/83 (2%) Frame = -1 Query: 586 RRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAE--DVLNRKFAFELSTPGET 413 RR+F L + + +FK P VI + V+ + D++ R FE+ T T Sbjct: 210 RRYFQLDENTIGYFKSELEKE---PLRVIPLKEVHKVQECKQSDIMMRDNLFEIVTTSRT 266 Query: 412 MYFVADSDKEKEDWINSIGRSIV 344 Y ADS +E WI ++ +IV Sbjct: 267 FYVQADSPEEMHSWIKAVSGAIV 289
>MYO10_BOVIN (P79114) Myosin-10 (Myosin X)| Length = 2052 Score = 37.7 bits (86), Expect = 0.024 Identities = 22/94 (23%), Positives = 47/94 (50%), Gaps = 3/94 (3%) Frame = -1 Query: 586 RRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPGETMY 407 +RWFVL+Q KL +F++ + + +G + V + K D +++ ++ T + Sbjct: 1230 KRWFVLRQAKLMYFENDSEEKL---KGTVEVRA---AKEIIDNTSKENGIDIIMADRTFH 1283 Query: 406 FVADSDKEKEDW---INSIGRSIVQHSRSMTDDE 314 +A+S ++ W ++ + S Q R M D++ Sbjct: 1284 LIAESPEDASQWFSVLSQVHASTDQEIREMHDEQ 1317
>GAB1_HUMAN (Q13480) GRB2-associated-binding protein 1 (GRB2-associated binder| 1) Length = 694 Score = 37.4 bits (85), Expect = 0.032 Identities = 25/84 (29%), Positives = 37/84 (44%), Gaps = 8/84 (9%) Frame = -1 Query: 586 RRWFVLKQGKLFWFKDSTV----TRASVPRGVIAVASCLTVKGAEDVLNRKFA----FEL 431 RRWFVL+ G+L D A P +I + C V ++F F++ Sbjct: 28 RRWFVLRSGRLTGDPDVLEYYKNDHAKKPIRIIDLNLCQQVDAGLTFNKKEFENSYIFDI 87 Query: 430 STPGETMYFVADSDKEKEDWINSI 359 +T Y VADS++E W+ I Sbjct: 88 NTIDRIFYLVADSEEEMNKWVRCI 111
>GAB2_HUMAN (Q9UQC2) GRB2-associated binding protein 2 (GRB2-associated binder| 2) (pp100) Length = 676 Score = 37.0 bits (84), Expect = 0.042 Identities = 22/87 (25%), Positives = 41/87 (47%), Gaps = 11/87 (12%) Frame = -1 Query: 586 RRWFVLKQGK-------LFWFKDSTVTRASVPRGVIAVASCLTVKGA----EDVLNRKFA 440 +RWF+L+ G+ L ++K+ + P +I + C V + L F Sbjct: 29 KRWFILRSGRMSGDPDVLEYYKND---HSKKPLRIINLNFCEQVDAGLTFNKKELQDSFV 85 Query: 439 FELSTPGETMYFVADSDKEKEDWINSI 359 F++ T T Y VA+++++ W+ SI Sbjct: 86 FDIKTSERTFYLVAETEEDMNKWVQSI 112
>GAB1_MOUSE (Q9QYY0) GRB2-associated-binding protein 1 (GRB2-associated binder| 1) Length = 695 Score = 36.2 bits (82), Expect = 0.071 Identities = 24/84 (28%), Positives = 37/84 (44%), Gaps = 8/84 (9%) Frame = -1 Query: 586 RRWFVLKQGKLFWFKDSTV----TRASVPRGVIAVASCLTVKGAEDVLNRKFA----FEL 431 RRWFVL+ G+L D A P +I + C V ++F F++ Sbjct: 28 RRWFVLRSGRLTGDPDVLEYYKNDHAKKPIRIIDLNLCQQVDAGLTFNKKEFENSYIFDI 87 Query: 430 STPGETMYFVADSDKEKEDWINSI 359 +T Y VADS+++ W+ I Sbjct: 88 NTIDRIFYLVADSEEDMNKWVRCI 111
>GAB2_RAT (Q9EQH1) GRB2-associated binding protein 2 (GRB2-associated binder| 2) Length = 665 Score = 36.2 bits (82), Expect = 0.071 Identities = 22/87 (25%), Positives = 40/87 (45%), Gaps = 11/87 (12%) Frame = -1 Query: 586 RRWFVLKQGK-------LFWFKDSTVTRASVPRGVIAVASCLTVKGA----EDVLNRKFA 440 +RWF+L+ G+ L ++K+ + P +I + C V + L F Sbjct: 31 KRWFILRSGRMSGDPDVLEYYKNE---HSKKPLRIINLNFCEQVDAGLTFNKKELQDSFV 87 Query: 439 FELSTPGETMYFVADSDKEKEDWINSI 359 F++ T T Y VA+++ + W+ SI Sbjct: 88 FDIKTSERTFYLVAETEADMNKWVQSI 114
>GAB2_MOUSE (Q9Z1S8) GRB2-associated-binding protein 2 (GRB2-associated binder| 2) (PH domain-containing adaptor molecule p97) Length = 665 Score = 36.2 bits (82), Expect = 0.071 Identities = 22/87 (25%), Positives = 40/87 (45%), Gaps = 11/87 (12%) Frame = -1 Query: 586 RRWFVLKQGK-------LFWFKDSTVTRASVPRGVIAVASCLTVKGA----EDVLNRKFA 440 +RWF+L+ G+ L ++K+ + P +I + C V + L F Sbjct: 31 KRWFILRSGRMSGDPDVLEYYKNE---HSKKPLRIINLNLCEQVDAGLTFNKKELQDSFV 87 Query: 439 FELSTPGETMYFVADSDKEKEDWINSI 359 F++ T T Y VA+++ + W+ SI Sbjct: 88 FDIKTSERTFYLVAETEADMNKWVQSI 114
>GAB1_MESAU (Q99PF6) GRB2-associated-binding protein 1 (GRB2-associated binder| 1) Length = 694 Score = 36.2 bits (82), Expect = 0.071 Identities = 24/84 (28%), Positives = 37/84 (44%), Gaps = 8/84 (9%) Frame = -1 Query: 586 RRWFVLKQGKLFWFKDSTV----TRASVPRGVIAVASCLTVKGAEDVLNRKFA----FEL 431 RRWFVL+ G+L D A P +I + C V ++F F++ Sbjct: 28 RRWFVLRSGRLTGDPDVLEYYKNDHAKKPIRIIDLNLCQQVDAGLTFNKKEFENSYIFDI 87 Query: 430 STPGETMYFVADSDKEKEDWINSI 359 +T Y VADS+++ W+ I Sbjct: 88 NTIDRIFYLVADSEEDMNKWVRCI 111
>MRIP_MOUSE (P97434) Myosin phosphatase Rho-interacting protein| (Rho-interacting protein 3) (p116Rip) (RIP3) Length = 1024 Score = 35.8 bits (81), Expect = 0.093 Identities = 21/84 (25%), Positives = 40/84 (47%) Frame = -1 Query: 586 RRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPGETMY 407 + WFVL L +++DS A+ G I +++C V E + R + F++ T Sbjct: 404 KHWFVLADQSLRYYRDSVAEEAADLDGEINLSTCYDV--TEYPVQRNYGFQIHTKEGEFT 461 Query: 406 FVADSDKEKEDWINSIGRSIVQHS 335 A + + +WI +I + ++ S Sbjct: 462 LSAMTSGIRRNWIQTIMKHVLPAS 485 Score = 30.4 bits (67), Expect = 3.9 Identities = 20/77 (25%), Positives = 38/77 (49%), Gaps = 1/77 (1%) Frame = -1 Query: 586 RRWFVL-KQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPGETM 410 RR+F+L + G L + D T ++P+G I + C V E +KF+ + TP + Sbjct: 71 RRFFILYEHGLLRYALDEMPT--TLPQGTINMNQCTDVVDGEARTGQKFSLCILTPDKEH 128 Query: 409 YFVADSDKEKEDWINSI 359 + A++ + W+ + Sbjct: 129 FIRAETKEIISGWLEML 145
>PLCG1_MOUSE (Q62077) 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase| gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148) Length = 1302 Score = 35.8 bits (81), Expect = 0.093 Identities = 21/60 (35%), Positives = 29/60 (48%), Gaps = 3/60 (5%) Frame = -1 Query: 511 RGVIAVASCLTVKGAEDVLNRKFAFELSTPGETMY---FVADSDKEKEDWINSIGRSIVQ 341 RGV+ V +C E NR F F +S P + ADS +E +DW+ I R + Q Sbjct: 873 RGVLDVPACQIAIRPEGKNNRLFVFSISMPSVAQWSLDVAADSQEELQDWVKKI-REVAQ 931
>PLCG1_RAT (P10686) 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase| gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148) Length = 1290 Score = 35.8 bits (81), Expect = 0.093 Identities = 21/60 (35%), Positives = 29/60 (48%), Gaps = 3/60 (5%) Frame = -1 Query: 511 RGVIAVASCLTVKGAEDVLNRKFAFELSTPGETMY---FVADSDKEKEDWINSIGRSIVQ 341 RGV+ V +C E NR F F +S P + ADS +E +DW+ I R + Q Sbjct: 873 RGVLDVPACQIAIRPEGKNNRLFVFSISMPSVAQWSLDVAADSQEELQDWVKKI-REVAQ 931
>ATG26_YARLI (Q6C8M8) Sterol 3-beta-glucosyltransferase (EC 2.4.1.173)| (Autophagy-related protein 26) Length = 1424 Score = 35.8 bits (81), Expect = 0.093 Identities = 21/82 (25%), Positives = 38/82 (46%), Gaps = 2/82 (2%) Frame = -1 Query: 586 RRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDV--LNRKFAFELSTPGET 413 R W VLK ++ DST P G I ++ L + +D + +F + P ++ Sbjct: 239 RYWCVLKNDSFSYYPDST--DVYFPAGTIDLSEALAAELCDDEGDVTEPESFRIVMPKKS 296 Query: 412 MYFVADSDKEKEDWINSIGRSI 347 + F ADS +W+ ++ + I Sbjct: 297 VLFKADSHSAAHEWVKALQKEI 318
>MRIP_RAT (Q9ERE6) Myosin phosphatase Rho-interacting protein| (Rho-interacting protein 3) (p116Rip) (RIP3) Length = 1029 Score = 35.8 bits (81), Expect = 0.093 Identities = 21/84 (25%), Positives = 40/84 (47%) Frame = -1 Query: 586 RRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPGETMY 407 + WFVL L +++DS A+ G I +++C V E + R + F++ T Sbjct: 409 KHWFVLADQSLRYYRDSVAEEAADLDGEINLSTCYDV--TEYPVQRNYGFQIHTKEGEFT 466 Query: 406 FVADSDKEKEDWINSIGRSIVQHS 335 A + + +WI +I + ++ S Sbjct: 467 LSAMTSGIRRNWIQTIMKHVLPTS 490 Score = 30.4 bits (67), Expect = 3.9 Identities = 20/77 (25%), Positives = 38/77 (49%), Gaps = 1/77 (1%) Frame = -1 Query: 586 RRWFVL-KQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPGETM 410 RR+F+L + G L + D T ++P+G I + C V E +KF+ + TP + Sbjct: 71 RRFFILYEHGLLRYALDEMPT--TLPQGTINMNQCTDVVDGEARTGQKFSLCILTPDKEH 128 Query: 409 YFVADSDKEKEDWINSI 359 + A++ + W+ + Sbjct: 129 FIRAETKEIISGWLEML 145
>CYH3_MOUSE (O08967) Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3| protein) (General receptor of phosphoinositides 1) (Grp1) (CLM-3) Length = 399 Score = 35.4 bits (80), Expect = 0.12 Identities = 29/102 (28%), Positives = 45/102 (44%), Gaps = 22/102 (21%) Frame = -1 Query: 586 RRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPGETMY 407 RRWF+L L++F+ +T PRG+I + + L+++ ED + FEL P Sbjct: 283 RRWFILTDNCLYYFEYTTDKE---PRGIIPLEN-LSIREVEDP-RKPNCFELYNPSHKGQ 337 Query: 406 FV----------------------ADSDKEKEDWINSIGRSI 347 + A S +EKE+W+ SI SI Sbjct: 338 VIKACKTEADGRVVEGNHVVYRISAPSPEEKEEWMKSIKASI 379
>CYH3_RAT (P97696) Cytohesin-3 (SEC7 homolog C) (msec7-3)| Length = 400 Score = 35.4 bits (80), Expect = 0.12 Identities = 29/102 (28%), Positives = 45/102 (44%), Gaps = 22/102 (21%) Frame = -1 Query: 586 RRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPGETMY 407 RRWF+L L++F+ +T PRG+I + + L+++ ED + FEL P Sbjct: 284 RRWFILTDNCLYYFEYTTDKE---PRGIIPLEN-LSIREVEDP-RKPNCFELYNPSHKGQ 338 Query: 406 FV----------------------ADSDKEKEDWINSIGRSI 347 + A S +EKE+W+ SI SI Sbjct: 339 VIKACKTEADGRVVEGNHVVYRISAPSPEEKEEWMKSIKASI 380
>CYH3_HUMAN (O43739) Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3| protein) (General receptor of phosphoinositides 1) (Grp1) Length = 400 Score = 35.4 bits (80), Expect = 0.12 Identities = 29/102 (28%), Positives = 45/102 (44%), Gaps = 22/102 (21%) Frame = -1 Query: 586 RRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPGETMY 407 RRWF+L L++F+ +T PRG+I + + L+++ ED + FEL P Sbjct: 284 RRWFILTDNCLYYFEYTTDKE---PRGIIPLEN-LSIREVEDP-RKPNCFELYNPSHKGQ 338 Query: 406 FV----------------------ADSDKEKEDWINSIGRSI 347 + A S +EKE+W+ SI SI Sbjct: 339 VIKACKTEADGRVVEGNHVVYRISAPSPEEKEEWMKSIKASI 380
>CYH1_RAT (P97694) Cytohesin-1 (SEC7 homolog A) (msec7-1)| Length = 398 Score = 35.4 bits (80), Expect = 0.12 Identities = 30/102 (29%), Positives = 46/102 (45%), Gaps = 22/102 (21%) Frame = -1 Query: 586 RRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTP----- 422 RRWF+L L++F+ T PRG+I + + L+++ ED + FEL P Sbjct: 280 RRWFILTDNCLYYFE---YTTDKEPRGIIPLEN-LSIREVED-SKKPNCFELYIPDNKDQ 334 Query: 421 ----------------GETMYFV-ADSDKEKEDWINSIGRSI 347 T+Y + A + +EKEDWI I +I Sbjct: 335 VIKACKTEADGRVVEGNHTVYRISAPTPEEKEDWIKCIKAAI 376
>CYH1_MOUSE (Q9QX11) Cytohesin-1 (CLM1)| Length = 398 Score = 35.4 bits (80), Expect = 0.12 Identities = 30/102 (29%), Positives = 46/102 (45%), Gaps = 22/102 (21%) Frame = -1 Query: 586 RRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTP----- 422 RRWF+L L++F+ T PRG+I + + L+++ ED + FEL P Sbjct: 280 RRWFILTDNCLYYFE---YTTDKEPRGIIPLEN-LSIREVED-SKKPNCFELYIPDNKDQ 334 Query: 421 ----------------GETMYFV-ADSDKEKEDWINSIGRSI 347 T+Y + A + +EKEDWI I +I Sbjct: 335 VIKACKTEADGRVVEGNHTVYRISAPTPEEKEDWIKCIKAAI 376
>CYH4_HUMAN (Q9UIA0) Cytohesin-4| Length = 394 Score = 35.0 bits (79), Expect = 0.16 Identities = 29/104 (27%), Positives = 45/104 (43%), Gaps = 22/104 (21%) Frame = -1 Query: 586 RRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPG---- 419 RRWF+L L++F+ T PRG+I + + L+V+ +D + F EL P Sbjct: 278 RRWFILTDNCLYYFE---FTTDKEPRGIIPLEN-LSVQKVDDP-KKPFCLELYNPSCRGQ 332 Query: 418 ------------------ETMYFVADSDKEKEDWINSIGRSIVQ 341 E+ A S +E++ WI SI SI + Sbjct: 333 KIKACKTDGDGRVVEGKHESYRISATSAEERDQWIESIRASITR 376
>MRIP_HUMAN (Q6WCQ1) Myosin phosphatase Rho-interacting protein| (Rho-interacting protein 3) (M-RIP) (RIP3) (p116Rip) Length = 1024 Score = 35.0 bits (79), Expect = 0.16 Identities = 20/80 (25%), Positives = 38/80 (47%) Frame = -1 Query: 586 RRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPGETMY 407 + WFVL L +++DS A+ G I +++C V E + R + F++ T Sbjct: 404 KHWFVLADQSLRYYRDSVAEEAADLDGEIDLSACYDV--TEYPVQRNYGFQIHTKEGEFT 461 Query: 406 FVADSDKEKEDWINSIGRSI 347 A + + +WI +I + + Sbjct: 462 LSAMTSGIRRNWIQTIMKHV 481 Score = 30.8 bits (68), Expect = 3.0 Identities = 20/77 (25%), Positives = 38/77 (49%), Gaps = 1/77 (1%) Frame = -1 Query: 586 RRWFVL-KQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPGETM 410 RR+F+L + G L + D T ++P+G I + C V E +KF+ + TP + Sbjct: 71 RRFFILYEHGLLRYALDEMPT--TLPQGTINMNQCTDVVDGEGRTGQKFSLCILTPEKEH 128 Query: 409 YFVADSDKEKEDWINSI 359 + A++ + W+ + Sbjct: 129 FIRAETKEIVSGWLEML 145
>CSX2_SCHPO (Q9UUE2) Protein csx2| Length = 870 Score = 35.0 bits (79), Expect = 0.16 Identities = 31/97 (31%), Positives = 46/97 (47%), Gaps = 8/97 (8%) Frame = -1 Query: 580 WFVLKQGKLFWFKD--STVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPGETMY 407 W VL GK+ + + ++ + P ++ TV+ A+ V +RKF FE+ TP Sbjct: 539 WVVLDHGKICEYANWKQSLELHTEPIDLLMA----TVRPAQSV-SRKFCFEVITPQTKRT 593 Query: 406 FVADSDKEKEDWIN----SIGRSIVQHSR--SMTDDE 314 + A S E WI SI SIVQ + SM +E Sbjct: 594 YQATSKAEMHSWIEAIQYSISESIVQKGKGTSMNSEE 630
>OSBP1_RABIT (P16258) Oxysterol-binding protein 1| Length = 809 Score = 34.7 bits (78), Expect = 0.21 Identities = 26/78 (33%), Positives = 42/78 (53%), Gaps = 2/78 (2%) Frame = -1 Query: 586 RRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASC-LTVKGAEDVLNRKFAFELSTPG-ET 413 RRWFVL G L +++ R + RG I +A+ +TV ED N F +S G +T Sbjct: 109 RRWFVLSNGLLSYYRSKAEMRHTC-RGTINLATANITV---EDSCN----FIISNGGAQT 160 Query: 412 MYFVADSDKEKEDWINSI 359 + A S+ E++ W+ ++ Sbjct: 161 YHLKASSEVERQRWVTAL 178
>CNKR2_HUMAN (Q8WXI2) Connector enhancer of kinase suppressor of ras 2| (Connector enhancer of KSR2) (CNK2) Length = 1034 Score = 34.7 bits (78), Expect = 0.21 Identities = 21/75 (28%), Positives = 37/75 (49%), Gaps = 1/75 (1%) Frame = -1 Query: 580 WFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPG-ETMYF 404 WFVLK L+W+ + +A G I++ + +E +K+AF+ P ++ YF Sbjct: 595 WFVLKDASLYWYINEEDEKA---EGFISLPEFKIDRASE--CRKKYAFKACHPKIKSFYF 649 Query: 403 VADSDKEKEDWINSI 359 A+ + W+N I Sbjct: 650 AAEHLDDMNRWLNRI 664
>OSBP1_HUMAN (P22059) Oxysterol-binding protein 1| Length = 807 Score = 34.7 bits (78), Expect = 0.21 Identities = 26/78 (33%), Positives = 42/78 (53%), Gaps = 2/78 (2%) Frame = -1 Query: 586 RRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASC-LTVKGAEDVLNRKFAFELSTPG-ET 413 RRWFVL G L +++ R + RG I +A+ +TV ED N F +S G +T Sbjct: 107 RRWFVLSNGLLSYYRSKAEMRHTC-RGTINLATANITV---EDSCN----FIISNGGAQT 158 Query: 412 MYFVADSDKEKEDWINSI 359 + A S+ E++ W+ ++ Sbjct: 159 YHLKASSEVERQRWVTAL 176
>CENB1_HUMAN (Q15027) Centaurin-beta 1 (Cnt-b1)| Length = 740 Score = 34.7 bits (78), Expect = 0.21 Identities = 30/109 (27%), Positives = 50/109 (45%), Gaps = 6/109 (5%) Frame = -1 Query: 586 RRWFVLKQGKLFW---FKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPGE 416 RRWF ++ +L + +KD V+ TVK D R+F FE+ + + Sbjct: 285 RRWFTIQSNQLVYQKKYKDPVTV-------VVDDLRLCTVKLCPDS-ERRFCFEVVSTSK 336 Query: 415 TMYFVADSDKEKEDWINSIGRSIVQ-HSRSMTDDEI--VDYDSGHPATG 278 + ADS++ + W++++ SI S++ DD SGH A G Sbjct: 337 SCLLQADSERLLQLWVSAVQSSIASAFSQARLDDSPRGPGQGSGHLAIG 385
>CNKR2_RAT (Q9Z1T4) Connector enhancer of kinase suppressor of ras 2| (Connector enhancer of KSR2) (CNK2) (Membrane-associated guanylate kinase-interacting protein) (MAGUIN) Length = 1032 Score = 34.7 bits (78), Expect = 0.21 Identities = 21/75 (28%), Positives = 37/75 (49%), Gaps = 1/75 (1%) Frame = -1 Query: 580 WFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPG-ETMYF 404 WFVLK L+W+ + +A G I++ + +E +K+AF+ P ++ YF Sbjct: 595 WFVLKDASLYWYINEEDEKA---EGFISLPEFKIDRASE--CRKKYAFKACHPKIKSFYF 649 Query: 403 VADSDKEKEDWINSI 359 A+ + W+N I Sbjct: 650 AAEHLDDMNRWLNRI 664
>CNKR2_MOUSE (Q80YA9) Connector enhancer of kinase suppressor of ras 2| (Connector enhancer of KSR2) (CNK2) Length = 1032 Score = 34.7 bits (78), Expect = 0.21 Identities = 21/75 (28%), Positives = 37/75 (49%), Gaps = 1/75 (1%) Frame = -1 Query: 580 WFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPG-ETMYF 404 WFVLK L+W+ + +A G I++ + +E +K+AF+ P ++ YF Sbjct: 595 WFVLKDASLYWYINEEDEKA---EGFISLPEFKIDRASE--CRKKYAFKACHPKIKSFYF 649 Query: 403 VADSDKEKEDWINSI 359 A+ + W+N I Sbjct: 650 AAEHLDDMNRWLNRI 664
>IRS2_HUMAN (Q9Y4H2) Insulin receptor substrate 2 (IRS-2)| Length = 1338 Score = 34.3 bits (77), Expect = 0.27 Identities = 19/71 (26%), Positives = 34/71 (47%) Frame = -1 Query: 529 TRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPGETMYFVADSDKEKEDWINSIGRS 350 ++A P+ VIA+ CL + D K+ L T E A++++E+E W ++ Sbjct: 84 SKAGAPKRVIALDCCLNINKRADA-KHKYLIALYTKDEYFAVAAENEQEQEGWYRAL-TD 141 Query: 349 IVQHSRSMTDD 317 +V R+ D Sbjct: 142 LVSEGRAAAGD 152
>IRS2_MOUSE (P81122) Insulin receptor substrate 2 (IRS-2) (4PS)| Length = 1321 Score = 33.9 bits (76), Expect = 0.35 Identities = 19/67 (28%), Positives = 33/67 (49%) Frame = -1 Query: 529 TRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPGETMYFVADSDKEKEDWINSIGRS 350 ++A P+ VIA+ CL + D K+ L T E A++++E+E W ++ Sbjct: 84 SKAGAPKRVIALDCCLNINKRADA-KHKYLIALYTKDEYFAVAAENEQEQEGWYRAL-TD 141 Query: 349 IVQHSRS 329 +V RS Sbjct: 142 LVSEGRS 148
>CYH1_HUMAN (Q15438) Cytohesin-1 (SEC7 homolog B2-1)| Length = 398 Score = 33.9 bits (76), Expect = 0.35 Identities = 29/102 (28%), Positives = 46/102 (45%), Gaps = 22/102 (21%) Frame = -1 Query: 586 RRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTP----- 422 RRWF+L L++F+ T PRG+I + + L+++ ED + FEL P Sbjct: 280 RRWFILTDNCLYYFE---YTTDKEPRGIIPLEN-LSIREVED-SKKPNCFELYIPDNKDQ 334 Query: 421 ----------------GETMYFV-ADSDKEKEDWINSIGRSI 347 T+Y + A + +EKE+WI I +I Sbjct: 335 VIKACKTEADGRVVEGNHTVYRISAPTPEEKEEWIKCIKAAI 376
>CYH1_CERAE (Q76MZ1) Cytohesin-1| Length = 398 Score = 33.9 bits (76), Expect = 0.35 Identities = 29/102 (28%), Positives = 46/102 (45%), Gaps = 22/102 (21%) Frame = -1 Query: 586 RRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTP----- 422 RRWF+L L++F+ T PRG+I + + L+++ ED + FEL P Sbjct: 280 RRWFILTDNCLYYFE---YTTDKEPRGIIPLEN-LSIREVED-SKKPNCFELYIPDNKDQ 334 Query: 421 ----------------GETMYFV-ADSDKEKEDWINSIGRSI 347 T+Y + A + +EKE+WI I +I Sbjct: 335 VIKACKTEADGRVVEGNHTVYRISAPTPEEKEEWIKCIKAAI 376
>CYH4_MOUSE (Q80YW0) Cytohesin-4| Length = 393 Score = 33.5 bits (75), Expect = 0.46 Identities = 28/104 (26%), Positives = 45/104 (43%), Gaps = 22/104 (21%) Frame = -1 Query: 586 RRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPG---- 419 RRWF+L L++F+ T PRG+I + + L+V+ ED + F EL P Sbjct: 278 RRWFILTDNCLYYFE---FTTDKEPRGIIPLEN-LSVQKVEDP-KKPFCLELYNPSCRGQ 332 Query: 418 ------------------ETMYFVADSDKEKEDWINSIGRSIVQ 341 E+ A + +E++ WI +I SI + Sbjct: 333 KIKACKTDGDGKVVEGKHESYRISAANAEERDQWIEAIRASITR 376
>RHG25_HUMAN (P42331) Rho-GTPase-activating protein 25| Length = 638 Score = 33.5 bits (75), Expect = 0.46 Identities = 24/87 (27%), Positives = 44/87 (50%), Gaps = 9/87 (10%) Frame = -1 Query: 586 RRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNR-KFAFEL------- 431 +R+FVL+ +L+++KD T+ P+G + + C + A + KF FE+ Sbjct: 58 QRYFVLRAQQLYYYKDEEDTK---PQGCMYLPGCTIKEIATNPEEAGKFVFEIIPASWDQ 114 Query: 430 STPGETMY-FVADSDKEKEDWINSIGR 353 + G+ Y +A S E E+W+ + R Sbjct: 115 NRMGQDSYVLMASSQAEMEEWVKFLRR 141
>ATG26_EMENI (Q5B4C9) Sterol 3-beta-glucosyltransferase (EC 2.4.1.173)| (Autophagy-related protein 26) Length = 1396 Score = 33.5 bits (75), Expect = 0.46 Identities = 22/82 (26%), Positives = 38/82 (46%), Gaps = 2/82 (2%) Frame = -1 Query: 586 RRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAE--DVLNRKFAFELSTPGET 413 R WF LK+ L ++ D + P G I + ++ E D F+++T T Sbjct: 308 RYWFSLKEDVLSYYADPS--NLYFPSGQIDLRYGISASLTEPKDKSRESRDFQVTTDHRT 365 Query: 412 MYFVADSDKEKEDWINSIGRSI 347 YF ADS ++W+ ++ + I Sbjct: 366 YYFRADSSVNAKEWVRALQKVI 387
>PLCG1_HUMAN (P19174) 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase| gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148) Length = 1290 Score = 33.1 bits (74), Expect = 0.60 Identities = 20/72 (27%), Positives = 33/72 (45%), Gaps = 3/72 (4%) Frame = -1 Query: 511 RGVIAVASCLTVKGAEDVLNRKFAFELSTPGETMYFV---ADSDKEKEDWINSIGRSIVQ 341 RGV+ V +C E NR F F +S + + ADS +E +DW+ I Sbjct: 873 RGVLDVPACQIAIRPEGKNNRLFVFSISMASVAHWSLDVAADSQEELQDWVKKIREVAQT 932 Query: 340 HSRSMTDDEIVD 305 +T+ +I++ Sbjct: 933 ADARLTEGKIME 944
>DAPP1_HUMAN (Q9UN19) Dual adapter for phosphotyrosine and 3-phosphotyrosine and| 3-phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32) Length = 280 Score = 33.1 bits (74), Expect = 0.60 Identities = 23/90 (25%), Positives = 39/90 (43%) Frame = -1 Query: 583 RWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPGETMYF 404 RWF L + +L +FKD + P ++ + C V+ + R F L P T Y Sbjct: 184 RWFTLHRNELKYFKDQ---MSPEPIRILDLTECSAVQ-FDYSQERVNCFCLVFPFRTFYL 239 Query: 403 VADSDKEKEDWINSIGRSIVQHSRSMTDDE 314 A + E ++WI + + Q + + E Sbjct: 240 CAKTGVEADEWIKILRWKLSQIRKQLNQGE 269
>CNKR1_HUMAN (Q969H4) Connector enhancer of kinase suppressor of ras 1| (Connector enhancer of KSR1) (hCNK1) (Connector enhancer of KSR-like) (CNK homolog protein 1) Length = 720 Score = 32.7 bits (73), Expect = 0.79 Identities = 21/77 (27%), Positives = 38/77 (49%), Gaps = 1/77 (1%) Frame = -1 Query: 586 RRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELS-TPGETM 410 RRWFVLK L+W++ +A G+I V++ G + +K+ F+L+ + Sbjct: 426 RRWFVLKGHTLYWYRQPQDEKA---EGLINVSNYSLESGHDQ--KKKYVFQLTHDVYKPF 480 Query: 409 YFVADSDKEKEDWINSI 359 F AD+ + W+ + Sbjct: 481 IFAADTLTDLSMWVRHL 497
>RASA3_HUMAN (Q14644) Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins| P4-binding protein) Length = 834 Score = 32.7 bits (73), Expect = 0.79 Identities = 25/100 (25%), Positives = 45/100 (45%), Gaps = 1/100 (1%) Frame = -1 Query: 586 RRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTV-KGAEDVLNRKFAFELSTPGETM 410 +RWF L + + K ++ P I + + L V K E+ K F++ P + Sbjct: 600 KRWFRLTNHEFTYHK----SKGDQPLYSIPIENILAVEKLEEESFKMKNMFQVIQPERAL 655 Query: 409 YFVADSDKEKEDWINSIGRSIVQHSRSMTDDEIVDYDSGH 290 Y A++ E +DWI+ + + + + +T Y SGH Sbjct: 656 YIQANNCVEAKDWIDILTKVSQCNQKRLTVYHPSAYLSGH 695
>OSP_DROME (Q27421) Protein outspread| Length = 1553 Score = 32.3 bits (72), Expect = 1.0 Identities = 21/74 (28%), Positives = 35/74 (47%), Gaps = 1/74 (1%) Frame = -1 Query: 586 RRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPGETMY 407 + WF L LF+++D V GV+ V S LT E +++ AF+L+T + Sbjct: 512 KHWFTLSGAALFYYRDPLCEERGVLDGVLDVNS-LTSVIPEPAASKQHAFQLTTWDKQRL 570 Query: 406 FVAD-SDKEKEDWI 368 +A S + W+ Sbjct: 571 VLASLSPSSRNSWL 584
>PLCG1_BOVIN (P08487) 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase| gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148) Length = 1291 Score = 32.3 bits (72), Expect = 1.0 Identities = 20/60 (33%), Positives = 29/60 (48%), Gaps = 3/60 (5%) Frame = -1 Query: 511 RGVIAVASCLTVKGAEDVLNRKFAFELSTPGE---TMYFVADSDKEKEDWINSIGRSIVQ 341 RGV+ V +C E NR F F +S ++ ADS +E +DW+ I R + Q Sbjct: 873 RGVLDVPACQIAVRPEGKNNRLFVFSISMASVAHWSLDVAADSQEELQDWVKKI-REVAQ 931
>PUR2_PYRFU (Q8U3N5) Phosphoribosylamine--glycine ligase (EC 6.3.4.13) (GARS)| (Glycinamide ribonucleotide synthetase) (Phosphoribosylglycinamide synthetase) Length = 439 Score = 32.3 bits (72), Expect = 1.0 Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 4/77 (5%) Frame = -1 Query: 541 DSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFEL----STPGETMYFVADSDKEKED 374 ++ V A RG+ AV T + A N+ +A E PG ++ V D KE ++ Sbjct: 77 EAGVVNALEERGIPAVGP--TKEAARLETNKAWAREFMERNKIPGRKLFRVFDDPKEMKE 134 Query: 373 WINSIGRSIVQHSRSMT 323 WI+ G+ +V +T Sbjct: 135 WIDEFGKPVVVKPLGLT 151
>OSBL9_HUMAN (Q96SU4) Oxysterol-binding protein-related protein 9 (OSBP-related| protein 9) (ORP-9) Length = 736 Score = 32.3 bits (72), Expect = 1.0 Identities = 21/85 (24%), Positives = 38/85 (44%), Gaps = 2/85 (2%) Frame = -1 Query: 583 RWFVL--KQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPGETM 410 RWFVL G L ++ RG + + + ED F ++ +T Sbjct: 22 RWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDED----DSTFTITVDQKTF 77 Query: 409 YFVADSDKEKEDWINSIGRSIVQHS 335 +F A E+E WI+++ +I++H+ Sbjct: 78 HFQARDADEREKWIHALEETILRHT 102
>DAPP1_MOUSE (Q9QXT1) Dual adapter for phosphotyrosine and 3-phosphotyrosine and| 3-phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32) Length = 280 Score = 32.3 bits (72), Expect = 1.0 Identities = 21/72 (29%), Positives = 34/72 (47%) Frame = -1 Query: 583 RWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPGETMYF 404 RWF L++ +L +FKD + P ++ + C V+ + R F L P T Y Sbjct: 184 RWFTLQRNELKYFKDQ---MSPEPIRILDLTECSAVQ-FDYSQERVNCFCLVFPFRTFYL 239 Query: 403 VADSDKEKEDWI 368 A + E ++WI Sbjct: 240 CAKTGVEADEWI 251
>CYH2_RAT (P63035) Cytohesin-2 (CLM2) (ARF nucleotide-binding site opener)| (ARNO protein) (SEC7 homolog B) Length = 400 Score = 32.0 bits (71), Expect = 1.3 Identities = 27/102 (26%), Positives = 46/102 (45%), Gaps = 22/102 (21%) Frame = -1 Query: 586 RRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTP----- 422 RRWF+L L++F+ T PRG+I + + L+++ +D + FEL P Sbjct: 279 RRWFILTDNCLYYFE---YTTDKEPRGIIPLEN-LSIREVDDP-RKPNCFELYIPNNKGQ 333 Query: 421 ---------------GETMYF--VADSDKEKEDWINSIGRSI 347 G M + A + +EK++WI SI ++ Sbjct: 334 LIKACKTEADGRVVEGNHMVYRISAPTQEEKDEWIKSIQAAV 375
>CYH2_MOUSE (P63034) Cytohesin-2 (CLM2) (SEC7 homolog B) (msec7-2)| Length = 400 Score = 32.0 bits (71), Expect = 1.3 Identities = 27/102 (26%), Positives = 46/102 (45%), Gaps = 22/102 (21%) Frame = -1 Query: 586 RRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTP----- 422 RRWF+L L++F+ T PRG+I + + L+++ +D + FEL P Sbjct: 279 RRWFILTDNCLYYFE---YTTDKEPRGIIPLEN-LSIREVDDP-RKPNCFELYIPNNKGQ 333 Query: 421 ---------------GETMYF--VADSDKEKEDWINSIGRSI 347 G M + A + +EK++WI SI ++ Sbjct: 334 LIKACKTEADGRVVEGNHMVYRISAPTQEEKDEWIKSIQAAV 375
>CYH2_HUMAN (Q99418) Cytohesin-2 (ARF nucleotide-binding site opener) (ARNO| protein) (ARF exchange factor) Length = 400 Score = 32.0 bits (71), Expect = 1.3 Identities = 27/102 (26%), Positives = 46/102 (45%), Gaps = 22/102 (21%) Frame = -1 Query: 586 RRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTP----- 422 RRWF+L L++F+ T PRG+I + + L+++ +D + FEL P Sbjct: 279 RRWFILTDNCLYYFE---YTTDKEPRGIIPLEN-LSIREVDDP-RKPNCFELYIPNNKGQ 333 Query: 421 ---------------GETMYF--VADSDKEKEDWINSIGRSI 347 G M + A + +EK++WI SI ++ Sbjct: 334 LIKACKTEADGRVVEGNHMVYRISAPTQEEKDEWIKSIQAAV 375
>CEND2_HUMAN (Q96P48) Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin| repeat and pleckstrin homology domain-containing protein 1) Length = 1210 Score = 32.0 bits (71), Expect = 1.3 Identities = 13/34 (38%), Positives = 22/34 (64%) Frame = -1 Query: 442 AFELSTPGETMYFVADSDKEKEDWINSIGRSIVQ 341 +F+L+TP F ADS+ EKE W+ ++ +I + Sbjct: 257 SFDLTTPYRIFSFSADSELEKEQWLEAMQGAIAE 290
>SYGP1_RAT (Q9QUH6) Ras GTPase-activating protein SynGAP (Synaptic| Ras-GTPase-activating protein 1) (Synaptic Ras-GAP 1) (Neuronal RasGAP) (p135 SynGAP) Length = 1293 Score = 31.6 bits (70), Expect = 1.8 Identities = 12/38 (31%), Positives = 23/38 (60%) Frame = -1 Query: 460 VLNRKFAFELSTPGETMYFVADSDKEKEDWINSIGRSI 347 +L ++F FE++T T F S E++ WI ++ R++ Sbjct: 198 ILGQEFCFEVTTSSGTKCFACRSAAERDKWIENLQRAV 235
>YAUA_SCHPO (Q10165) Hypothetical protein C26A3.10 in chromosome I| Length = 923 Score = 31.6 bits (70), Expect = 1.8 Identities = 23/79 (29%), Positives = 37/79 (46%), Gaps = 3/79 (3%) Frame = -1 Query: 586 RRWFVLKQGKLFWF---KDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPGE 416 + W V++ G L+ + KDS + S A A + +G R+F FE+ TP Sbjct: 555 KHWIVVENGSLWEYANWKDSVKSNVSSISLKHASADKVRKQG------RRFCFEVVTPKL 608 Query: 415 TMYFVADSDKEKEDWINSI 359 + A S +E + WI +I Sbjct: 609 KRLYQATSAEEMDSWIEAI 627
>SYGP1_HUMAN (Q96PV0) Ras GTPase-activating protein SynGAP (Synaptic| Ras-GTPase-activating protein 1) (Synaptic Ras-GAP 1) (Neuronal RasGAP) Length = 1328 Score = 31.6 bits (70), Expect = 1.8 Identities = 12/38 (31%), Positives = 23/38 (60%) Frame = -1 Query: 460 VLNRKFAFELSTPGETMYFVADSDKEKEDWINSIGRSI 347 +L ++F FE++T T F S E++ WI ++ R++ Sbjct: 198 ILGQEFCFEVTTSSGTKCFACRSAAERDKWIENLQRAV 235
>ATG26_NEUCR (Q7S1I0) Sterol 3-beta-glucosyltransferase (EC 2.4.1.173)| (Autophagy-related protein 26) Length = 1553 Score = 31.2 bits (69), Expect = 2.3 Identities = 27/93 (29%), Positives = 41/93 (44%) Frame = -1 Query: 586 RRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPGETMY 407 R WF LK L +++D P G I + ++ D F +ST T + Sbjct: 393 RYWFRLKGDVLSYYQDPK--DHYFPAGQIDLRYGISAS-VNDKEKEGNYFSVSTHHRTYH 449 Query: 406 FVADSDKEKEDWINSIGRSIVQHSRSMTDDEIV 308 F ADS + ++W+ S+ R I RS D + V Sbjct: 450 FKADSARSAKEWVKSLQRVIF---RSHNDGDSV 479
>DDFL1_MOUSE (Q5U464) Development and differentiation enhancing factor-like 1| Length = 904 Score = 31.2 bits (69), Expect = 2.3 Identities = 22/71 (30%), Positives = 37/71 (52%) Frame = -1 Query: 448 KFAFELSTPGETMYFVADSDKEKEDWINSIGRSIVQHSRSMTDDEIVDYDSGHPATGRKS 269 K F+L T T +F A+ ++E E W+ S++Q+S+ D+ + + G P+ G+ S Sbjct: 360 KRCFDLVTHNRTYHFHAEDEQECEAWV-----SVLQNSK---DEALSNAFHGEPSGGQWS 411 Query: 268 *VRRLIGEQKD 236 RL E D Sbjct: 412 WGTRLDTEPHD 422
>SWAP_CAEEL (Q10580) Protein SWAP (Suppressor of white apricot protein homolog)| Length = 749 Score = 31.2 bits (69), Expect = 2.3 Identities = 21/64 (32%), Positives = 27/64 (42%) Frame = +3 Query: 342 WTMERPMELIQSSFSLSESATKYMVSPGVESSKANLRLSTSSAPLTVRQEATAMTPRGTD 521 W M +P+E S L+ A VS SS +L LST PL RQ + D Sbjct: 440 WRMYQPIEQNLSPLVLNSPAPPSAVSSPGPSSLMSLNLSTPEPPLNRRQRRRLLDSSRLD 499 Query: 522 ARVT 533 +T Sbjct: 500 ESIT 503
>ATG26_CANAL (Q5A950) Sterol 3-beta-glucosyltransferase (EC 2.4.1.173)| (Autophagy-related protein 26) (UDP-glycosyltransferase 51) Length = 1513 Score = 31.2 bits (69), Expect = 2.3 Identities = 14/44 (31%), Positives = 24/44 (54%) Frame = -1 Query: 439 FELSTPGETMYFVADSDKEKEDWINSIGRSIVQHSRSMTDDEIV 308 F+L T +T F DS W N+I + I QH+ + ++ E++ Sbjct: 489 FKLVTKKKTYKFSCDSSFSARQWCNNITKLIFQHNNANSNGEVL 532
>ALS2_PANTR (Q5BIW4) Alsin (Amyotrophic lateral sclerosis protein 2 homolog)| Length = 1657 Score = 31.2 bits (69), Expect = 2.3 Identities = 14/48 (29%), Positives = 28/48 (58%) Frame = -1 Query: 436 ELSTPGETMYFVADSDKEKEDWINSIGRSIVQHSRSMTDDEIVDYDSG 293 +++TP E ++ + +EK W+ +I +++ Q R M+D + Y SG Sbjct: 975 KITTPEEQFTLISSTPQEKTKWLRAISQAVDQALRGMSD--LPPYGSG 1020
>ALS2_HUMAN (Q96Q42) Alsin (Amyotrophic lateral sclerosis protein 2)| Length = 1657 Score = 31.2 bits (69), Expect = 2.3 Identities = 14/48 (29%), Positives = 28/48 (58%) Frame = -1 Query: 436 ELSTPGETMYFVADSDKEKEDWINSIGRSIVQHSRSMTDDEIVDYDSG 293 +++TP E ++ + +EK W+ +I +++ Q R M+D + Y SG Sbjct: 975 KITTPEEQFTLISSTPQEKTKWLRAISQAVDQALRGMSD--LPPYGSG 1020
>GRP1_CAEEL (P34512) GTP exchange factor for ARFs 1| Length = 393 Score = 30.8 bits (68), Expect = 3.0 Identities = 25/98 (25%), Positives = 45/98 (45%), Gaps = 20/98 (20%) Frame = -1 Query: 586 RRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPGE--- 416 +RWFVL + L++F T P+G+I +A+ K + +R F FE+ + + Sbjct: 285 KRWFVLSENCLYYFDQMT---DKEPKGIITLANVGIRK--VEAPSRPFMFEIFSLSDGQI 339 Query: 415 ----------------TMYFV-ADSDKEKEDWINSIGR 353 ++Y + A +D++ WIN+I R Sbjct: 340 KACKTEQDGRLVEGRHSIYKICAVNDEDMRSWINAISR 377
>INT2_SALTI (P62592) Integrase/recombinase (E2 protein)| Length = 337 Score = 30.8 bits (68), Expect = 3.0 Identities = 17/52 (32%), Positives = 25/52 (48%), Gaps = 3/52 (5%) Frame = +3 Query: 138 IISVEDMYQKNLDKHDKDDVEQ*SLQMPPTPH---RSFCSPINRRTYDLRPV 284 ++ MY + + K VEQ + P TPH SF + + R YD+R V Sbjct: 246 VVRRHHMYDQTFQRAFKRAVEQAGITKPATPHTLRHSFATALLRSGYDIRTV 297
>INT2_PSEAE (P62591) Integrase/recombinase (E2 protein)| Length = 337 Score = 30.8 bits (68), Expect = 3.0 Identities = 17/52 (32%), Positives = 25/52 (48%), Gaps = 3/52 (5%) Frame = +3 Query: 138 IISVEDMYQKNLDKHDKDDVEQ*SLQMPPTPH---RSFCSPINRRTYDLRPV 284 ++ MY + + K VEQ + P TPH SF + + R YD+R V Sbjct: 246 VVRRHHMYDQTFQRAFKRAVEQAGITKPATPHTLRHSFATALLRSGYDIRTV 297
>INT2_ECOLI (P62590) Integrase/recombinase (E2 protein)| Length = 337 Score = 30.8 bits (68), Expect = 3.0 Identities = 17/52 (32%), Positives = 25/52 (48%), Gaps = 3/52 (5%) Frame = +3 Query: 138 IISVEDMYQKNLDKHDKDDVEQ*SLQMPPTPH---RSFCSPINRRTYDLRPV 284 ++ MY + + K VEQ + P TPH SF + + R YD+R V Sbjct: 246 VVRRHHMYDQTFQRAFKRAVEQAGITKPATPHTLRHSFATALLRSGYDIRTV 297
>ATG26_PICPA (Q9Y751) Sterol 3-beta-glucosyltransferase (EC 2.4.1.173)| (Autophagy-related protein 26) (UDP-glycosyltransferase 51) (Pexophagy zeocin-resistent mutant protein 4) (Peroxisome degradation protein 3) Length = 1211 Score = 30.4 bits (67), Expect = 3.9 Identities = 25/82 (30%), Positives = 35/82 (42%), Gaps = 2/82 (2%) Frame = -1 Query: 586 RRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVL--NRKFAFELSTPGET 413 RRW VLK + +ST P I + L V+ + L N+ F+L T T Sbjct: 267 RRWAVLKGNYFRLYANST--ERYFPSLNIDLRFLLKVELSNPNLEENKPTVFKLITEART 324 Query: 412 MYFVADSDKEKEDWINSIGRSI 347 YF ADS W+ + + I Sbjct: 325 HYFQADSLDNARSWVTDLRKHI 346
>RASA2_RAT (Q63713) Ras GTPase-activating protein 2 (GAP1m)| Length = 847 Score = 30.0 bits (66), Expect = 5.1 Identities = 24/87 (27%), Positives = 41/87 (47%), Gaps = 2/87 (2%) Frame = -1 Query: 586 RRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDV-LNRKFAFELSTPGETM 410 +RWF L +L + K I V + L V+ E+ N+K F++ +T+ Sbjct: 627 KRWFCLTSKELTYHKQQGKDAIYT----IPVKNILAVEKLEESSFNKKNMFQVIHTEKTL 682 Query: 409 YFVADSDKEKEDWINSIGR-SIVQHSR 332 Y A++ E +WI+ + R S H+R Sbjct: 683 YIQANNCVEANEWIDMLCRVSRCNHNR 709
>RASA1_RAT (P50904) Ras GTPase-activating protein 1 (GTPase-activating| protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP) Length = 1038 Score = 30.0 bits (66), Expect = 5.1 Identities = 20/87 (22%), Positives = 41/87 (47%), Gaps = 11/87 (12%) Frame = -1 Query: 586 RRW----FVLK--QGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFEL-- 431 +RW F+L+ +L +F+ RA+ P+G+I ++ C + + R F++ Sbjct: 479 KRWKNLYFILEGSDAQLIYFESEK--RATKPKGLIDLSVCSVYVVHDSLFGRPNCFQIVV 536 Query: 430 ---STPGETMYFVADSDKEKEDWINSI 359 S YF ++ ++ EDW+ + Sbjct: 537 QHFSEEHYIFYFAGETPEQAEDWMKGL 563
>RASA1_BOVIN (P09851) Ras GTPase-activating protein 1 (GTPase-activating| protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP) Length = 1044 Score = 30.0 bits (66), Expect = 5.1 Identities = 20/87 (22%), Positives = 41/87 (47%), Gaps = 11/87 (12%) Frame = -1 Query: 586 RRW----FVLK--QGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFEL-- 431 +RW F+L+ +L +F+ RA+ P+G+I ++ C + + R F++ Sbjct: 485 KRWKNLYFILEGSDAQLIYFESEK--RATKPKGLIDLSVCSVYVVHDSLFGRPNCFQIVV 542 Query: 430 ---STPGETMYFVADSDKEKEDWINSI 359 S YF ++ ++ EDW+ + Sbjct: 543 QHFSEEHYIFYFAGETPEQAEDWMKGL 569
>PLEK_HUMAN (P08567) Pleckstrin (Platelet p47 protein)| Length = 350 Score = 30.0 bits (66), Expect = 5.1 Identities = 18/79 (22%), Positives = 39/79 (49%), Gaps = 1/79 (1%) Frame = -1 Query: 580 WFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFEL-STPGETMYF 404 W VL + + ++K + + P+G+I + +D R F F++ +T + +F Sbjct: 25 WVVLLEDGIEFYKKKS---DNSPKGMIPLKGSTLTSPCQDFGKRMFVFKITTTKQQDHFF 81 Query: 403 VADSDKEKEDWINSIGRSI 347 A +E++ W+ I ++I Sbjct: 82 QAAFLEERDAWVRDIKKAI 100
>RASA1_HUMAN (P20936) Ras GTPase-activating protein 1 (GTPase-activating| protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP) Length = 1047 Score = 30.0 bits (66), Expect = 5.1 Identities = 20/87 (22%), Positives = 41/87 (47%), Gaps = 11/87 (12%) Frame = -1 Query: 586 RRW----FVLK--QGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFEL-- 431 +RW F+L+ +L +F+ RA+ P+G+I ++ C + + R F++ Sbjct: 488 KRWKNLYFILEGSDAQLIYFESEK--RATKPKGLIDLSVCSVYVVHDSLFGRPNCFQIVV 545 Query: 430 ---STPGETMYFVADSDKEKEDWINSI 359 S YF ++ ++ EDW+ + Sbjct: 546 QHFSEEHYIFYFAGETPEQAEDWMKGL 572
>RASA3_MOUSE (Q60790) Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins| P4-binding protein) (GapIII) Length = 834 Score = 30.0 bits (66), Expect = 5.1 Identities = 24/100 (24%), Positives = 46/100 (46%), Gaps = 1/100 (1%) Frame = -1 Query: 586 RRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNR-KFAFELSTPGETM 410 +RWF L + + K ++ P I + + L V+ E+ R K F++ P + Sbjct: 600 KRWFRLTNHEFTYQK----SKGDQPLCNIPIENILAVERLEEESFRMKNMFQVIQPERAL 655 Query: 409 YFVADSDKEKEDWINSIGRSIVQHSRSMTDDEIVDYDSGH 290 Y A++ E +DWI+ + + + + +T Y +GH Sbjct: 656 YIQANNCVEAKDWIDILTKVSQCNQKRLTVFHPSAYLNGH 695
>BTKL_DROME (P08630) Tyrosine-protein kinase Btk29A (EC 2.7.10.2) (Dsrc28C)| Length = 786 Score = 30.0 bits (66), Expect = 5.1 Identities = 12/34 (35%), Positives = 23/34 (67%) Frame = -1 Query: 430 STPGETMYFVADSDKEKEDWINSIGRSIVQHSRS 329 + P T+Y +A+S+KE+ +WI +I R + + S + Sbjct: 156 AVPQYTLYVIANSEKERSEWIRAI-RQVCEDSNT 188
>IRS1_RAT (P35570) Insulin receptor substrate 1 (IRS-1) (pp185)| Length = 1235 Score = 29.6 bits (65), Expect = 6.7 Identities = 16/56 (28%), Positives = 26/56 (46%) Frame = -1 Query: 526 RASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPGETMYFVADSDKEKEDWINSI 359 ++S P+ I + SC + D N K L T E ADS+ E++ W ++ Sbjct: 56 KSSAPKRSIPLESCFNINKRADSKN-KHLVALYTRDEHFAIAADSEAEQDSWYQAL 110
>RGA2_YEAST (Q06407) Rho-type GTPase-activating protein 2| Length = 1009 Score = 29.6 bits (65), Expect = 6.7 Identities = 39/157 (24%), Positives = 63/157 (40%), Gaps = 8/157 (5%) Frame = +3 Query: 75 SIVVSRPKITDNNH*HYTGAHIISVEDMYQKNLDKHDKDDVE-Q*SLQMPPTPHRSFCSP 251 SIVV P+I ++N S+ D ++ DK D D+ E + + P SP Sbjct: 277 SIVVKDPRIPNSNS---NANRFFSIYD--KEETDKDDTDNKENEIIVNTPRNSTDKITSP 331 Query: 252 IN-----RRTYDLRPVAGWPLS*STISSSVMDRECWTMERPMELIQSSFSLSESATKYM- 413 +N + ++ P G L+ S E E +SS + S +K M Sbjct: 332 LNSPMAVQMNEEVEPPHGLALTLS--------------EATKENNKSSQGIQTSTSKSMN 377 Query: 414 -VSPGVESSKANLRLSTSSAPLTVRQEATAMTPRGTD 521 VSP + ++ STSS+ L + + P+ D Sbjct: 378 HVSPITRTDTVEMKTSTSSSTLRLSDNGSFSRPQTAD 414
>RASA2_MOUSE (P58069) Ras GTPase-activating protein 2 (GAP1m)| Length = 848 Score = 29.6 bits (65), Expect = 6.7 Identities = 26/91 (28%), Positives = 44/91 (48%), Gaps = 6/91 (6%) Frame = -1 Query: 586 RRWFVLKQGKLFWF----KDSTVTRASVPRGVIAVASCLTVKGAED-VLNRKFAFELSTP 422 +RWF L +L + KD+ T I V + L V+ E+ N+K F++ Sbjct: 628 KRWFCLTSRELTYHRQQGKDAIYT--------IPVKNILAVEKLEEGSFNKKNMFQVIHT 679 Query: 421 GETMYFVADSDKEKEDWINSIGR-SIVQHSR 332 +T+Y A++ E +WI+ + R S H+R Sbjct: 680 EKTLYIQANNCVEANEWIDVLCRVSRCNHNR 710
>AKAP3_MOUSE (O88987) A-kinase anchor protein 3 (Protein kinase A-anchoring| protein 3) (PRKA3) (A-kinase anchor protein 110 kDa) (AKAP 110) Length = 864 Score = 29.6 bits (65), Expect = 6.7 Identities = 13/41 (31%), Positives = 22/41 (53%) Frame = -1 Query: 430 STPGETMYFVADSDKEKEDWINSIGRSIVQHSRSMTDDEIV 308 S PG+ F D +D+ NSI + I+ ++ S+ D +V Sbjct: 260 SLPGDQKLFRTSPDNRPDDFSNSISQGIMTYANSVVSDMMV 300
>IRS1_HUMAN (P35568) Insulin receptor substrate 1 (IRS-1)| Length = 1242 Score = 29.6 bits (65), Expect = 6.7 Identities = 16/56 (28%), Positives = 26/56 (46%) Frame = -1 Query: 526 RASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPGETMYFVADSDKEKEDWINSI 359 ++S P+ I + SC + D N K L T E ADS+ E++ W ++ Sbjct: 56 KSSAPKRSIPLESCFNINKRADSKN-KHLVALYTRDEHFAIAADSEAEQDSWYQAL 110
>FGD1_MOUSE (P52734) FYVE, RhoGEF and PH domain-containing protein 1| (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF) Length = 960 Score = 29.6 bits (65), Expect = 6.7 Identities = 11/44 (25%), Positives = 27/44 (61%) Frame = -1 Query: 457 LNRKFAFELSTPGETMYFVADSDKEKEDWINSIGRSIVQHSRSM 326 LN F +S ++ A +++EK+DW+ +I ++++H +++ Sbjct: 651 LNMPRTFLVSGKQRSLELQARTEEEKKDWVQAINSTLLKHEQTL 694
>TGFB4_MOUSE (Q64280) Transforming growth factor beta-4 precursor (TGF-beta-4)| (Lefty protein) (Lefty-1 protein) (STRA3 protein) Length = 368 Score = 29.6 bits (65), Expect = 6.7 Identities = 20/66 (30%), Positives = 30/66 (45%), Gaps = 7/66 (10%) Frame = +3 Query: 369 IQSSFSLSESATKYMV-------SPGVESSKANLRLSTSSAPLTVRQEATAMTPRGTDAR 527 + F +SE++T +V P E +A LRL P T + ++P AR Sbjct: 85 VAGRFLVSETSTHLLVFGMEQRLPPNSELVQAVLRLFQEPVPRTALRRQKRLSPHSARAR 144 Query: 528 VTVESL 545 VT+E L Sbjct: 145 VTIEWL 150
>LEFTB_MOUSE (P57785) Left-right determination factor B precursor (Lefty-2| protein) Length = 368 Score = 29.6 bits (65), Expect = 6.7 Identities = 20/66 (30%), Positives = 30/66 (45%), Gaps = 7/66 (10%) Frame = +3 Query: 369 IQSSFSLSESATKYMV-------SPGVESSKANLRLSTSSAPLTVRQEATAMTPRGTDAR 527 + F +SE++T +V P E +A LRL P T + ++P AR Sbjct: 85 VAGRFLMSETSTHLLVFGMEQRLPPNSELVQAVLRLFQEPVPRTALRRFERLSPHSARAR 144 Query: 528 VTVESL 545 VT+E L Sbjct: 145 VTIEWL 150
>IRS1_MOUSE (P35569) Insulin receptor substrate 1 (IRS-1)| Length = 1233 Score = 29.6 bits (65), Expect = 6.7 Identities = 16/56 (28%), Positives = 26/56 (46%) Frame = -1 Query: 526 RASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPGETMYFVADSDKEKEDWINSI 359 ++S P+ I + SC + D N K L T E ADS+ E++ W ++ Sbjct: 56 KSSAPKRSIPLESCFNINKRADSKN-KHLVALYTRDEHFAIAADSEAEQDSWYQAL 110
>EGT2_YEAST (P42835) Protein EGT2 precursor (Early G1 transcript 2)| Length = 1041 Score = 29.6 bits (65), Expect = 6.7 Identities = 27/107 (25%), Positives = 44/107 (41%) Frame = +3 Query: 168 NLDKHDKDDVEQ*SLQMPPTPHRSFCSPINRRTYDLRPVAGWPLS*STISSSVMDRECWT 347 N+D DD + PT S S ++ + VA S I SS +D + Sbjct: 310 NIDSTTSDDTTSSDAAITPTYSNSTLSSYTSQSSAIPEVAVTASLSSGILSSTVDGASTS 369 Query: 348 MERPMELIQSSFSLSESATKYMVSPGVESSKANLRLSTSSAPLTVRQ 488 + M + + S SE A+ +S SS +N +T S+ L+ + Sbjct: 370 ADASMSAVSTVSSSSEQASSSSISLSAPSS-SNSTFTTPSSSLSATE 415
>IRS1_CERAE (Q28224) Insulin receptor substrate 1 (IRS-1)| Length = 1251 Score = 29.6 bits (65), Expect = 6.7 Identities = 16/56 (28%), Positives = 26/56 (46%) Frame = -1 Query: 526 RASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPGETMYFVADSDKEKEDWINSI 359 ++S P+ I + SC + D N K L T E ADS+ E++ W ++ Sbjct: 56 KSSAPKRSIPLESCFNINKRADSKN-KHLVALYTRDEHFAIAADSEAEQDSWYQAL 110
>VG22_ICHV1 (Q00105) Hypothetical gene 22 protein| Length = 1403 Score = 29.3 bits (64), Expect = 8.7 Identities = 20/52 (38%), Positives = 26/52 (50%) Frame = -1 Query: 535 TVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPGETMYFVADSDKEK 380 TVT A +PRG +A VLNR A E +TPG V+D D ++ Sbjct: 1319 TVTAADIPRGQLA------------VLNRDTAVEYATPGTP---VSDRDHQR 1355
>FGD1_HUMAN (P98174) FYVE, RhoGEF and PH domain-containing protein 1| (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF) Length = 961 Score = 29.3 bits (64), Expect = 8.7 Identities = 11/44 (25%), Positives = 27/44 (61%) Frame = -1 Query: 457 LNRKFAFELSTPGETMYFVADSDKEKEDWINSIGRSIVQHSRSM 326 LN F +S ++ A +++EK+DW+ +I ++++H +++ Sbjct: 652 LNLPRTFLVSGKQRSLELQARTEEEKKDWVQAINSTLLKHEQTL 695
>C43BP_MOUSE (Q9EQG9) Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP)| (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11) Length = 624 Score = 29.3 bits (64), Expect = 8.7 Identities = 18/75 (24%), Positives = 32/75 (42%) Frame = -1 Query: 583 RWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPGETMYF 404 RW VLK L ++K T RG I ++ + D + F++S Y Sbjct: 43 RWVVLKNNTLSYYKSEDETEYGC-RGSICLSKAVITPHDFD----ECRFDISVNDSVWYL 97 Query: 403 VADSDKEKEDWINSI 359 A + ++ W+++I Sbjct: 98 RAQDPEHRQQWVDAI 112
>RPOB_GUITH (O78485) DNA-directed RNA polymerase beta chain (EC 2.7.7.6) (PEP)| (Plastid-encoded RNA polymerase beta subunit) (RNA polymerase beta subunit) Length = 1096 Score = 29.3 bits (64), Expect = 8.7 Identities = 14/50 (28%), Positives = 23/50 (46%) Frame = +3 Query: 372 QSSFSLSESATKYMVSPGVESSKANLRLSTSSAPLTVRQEATAMTPRGTD 521 Q + ++ KY ++PG + R++T P+ RQE T P D Sbjct: 460 QPIYLTADQEDKYRIAPGDITLDETNRIATKIVPIKYRQEFTTTKPNQVD 509
>Y2023_FUSNN (Q8RHJ4) UPF0090 protein FN2023| Length = 156 Score = 29.3 bits (64), Expect = 8.7 Identities = 16/51 (31%), Positives = 26/51 (50%) Frame = -1 Query: 466 EDVLNRKFAFELSTPGETMYFVADSDKEKEDWINSIGRSIVQHSRSMTDDE 314 E+++ KF E+S+PG + K+ ED+ IG I H + DD+ Sbjct: 68 EELIEHKFFLEVSSPG-----LERPLKKLEDYTRFIGEKITLHLKHKLDDK 113 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 55,952,076 Number of Sequences: 219361 Number of extensions: 997873 Number of successful extensions: 3228 Number of sequences better than 10.0: 109 Number of HSP's better than 10.0 without gapping: 3125 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 3198 length of database: 80,573,946 effective HSP length: 106 effective length of database: 57,321,680 effective search space used: 5044307840 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
