ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | rbags18b23 |
|---|---|
| Clone Library Name | barley_pub |
>HEM3_PEA (Q43082) Porphobilinogen deaminase, chloroplast precursor (EC| 2.5.1.61) (PBG) (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 369 Score = 213 bits (541), Expect = 6e-55 Identities = 100/135 (74%), Positives = 119/135 (88%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GLKRL+M E TS LS+D+MLPAVAQGAIGIACRSNDDKM EYL+SLNHE+TRLA++CER Sbjct: 234 GLKRLNMTENVTSTLSIDDMLPAVAQGAIGIACRSNDDKMAEYLASLNHEETRLAISCER 293 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSGTYSFDDMVAIGQD 319 FL+ LDG+CRTPIA YA RDKDGNC FRGL+ASPDG+ V ETSR G+Y+++DM+ IG+D Sbjct: 294 AFLTTLDGSCRTPIAGYASRDKDGNCLFRGLVASPDGTRVLETSRIGSYTYEDMMKIGKD 353 Query: 318 AGHELKSKAGPGFFD 274 AG EL S+AGPGFF+ Sbjct: 354 AGEELLSRAGPGFFN 368
>HEM3_ARATH (Q43316) Porphobilinogen deaminase, chloroplast precursor (EC| 2.5.1.61) (PBG) (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 382 Score = 200 bits (508), Expect = 4e-51 Identities = 94/134 (70%), Positives = 113/134 (84%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GLKRL M E S+LS+DEMLPAVAQGAIGIACR++DDKM YL+SLNHE+TRLA++CER Sbjct: 247 GLKRLSMTENVASILSLDEMLPAVAQGAIGIACRTDDDKMATYLASLNHEETRLAISCER 306 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSGTYSFDDMVAIGQD 319 FL LDG+CRTPIA YA +D++GNC FRGL+ASPDG+ V ETSR G Y ++DMV +G+D Sbjct: 307 AFLETLDGSCRTPIAGYASKDEEGNCIFRGLVASPDGTKVLETSRKGPYVYEDMVKMGKD 366 Query: 318 AGHELKSKAGPGFF 277 AG EL S+AGPGFF Sbjct: 367 AGQELLSRAGPGFF 380
>HEM3_BRUME (Q8YJB0) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 314 Score = 117 bits (294), Expect = 2e-26 Identities = 63/138 (45%), Positives = 86/138 (62%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GL+RL +A+ T VL PA QGAIGI R D+++ L+ L H +T++A+ACER Sbjct: 180 GLRRLGLADVITDVLDPSVFPPAPGQGAIGIESRIGDERIDVLLAPLAHRETQIALACER 239 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSGTYSFDDMVAIGQD 319 FL LDG+CRTPIA A + D SFRG++ +PDG +E + G S D A+G D Sbjct: 240 AFLGALDGSCRTPIAGLATVEGD-RLSFRGMILTPDGRQAHEVTAEGVVS--DAAALGTD 296 Query: 318 AGHELKSKAGPGFFDGLQ 265 A + +++ AGP FFDG Q Sbjct: 297 AANRVRAMAGPHFFDGWQ 314
>HEM3_BRUSU (Q8FYI6) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 314 Score = 116 bits (291), Expect = 5e-26 Identities = 62/138 (44%), Positives = 86/138 (62%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GL+RL +A+ T +L PA QGAIGI R D+++ L+ L H +T++A+ACER Sbjct: 180 GLRRLGLADVITDLLDPSVFPPAPGQGAIGIESRIGDERIDVLLAPLAHRETQIALACER 239 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSGTYSFDDMVAIGQD 319 FL LDG+CRTPIA A + D SFRG++ +PDG +E + G S D A+G D Sbjct: 240 AFLGALDGSCRTPIAGLATVEGD-RLSFRGMILTPDGRQAHEVTAEGVVS--DAAALGTD 296 Query: 318 AGHELKSKAGPGFFDGLQ 265 A + +++ AGP FFDG Q Sbjct: 297 AANRVRAMAGPHFFDGWQ 314
>HEM3_AGRT5 (Q8UC46) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 309 Score = 108 bits (270), Expect = 1e-23 Identities = 61/136 (44%), Positives = 80/136 (58%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GLKRL T +L E PA AQGAIG+ R D +M + L+ +N T AV CER Sbjct: 175 GLKRLGKDNVPTEILDPKEFPPAPAQGAIGVESRIGDARMDKLLAPINDRPTYDAVTCER 234 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSGTYSFDDMVAIGQD 319 FL+ LDG+CRTPIA YA + D N F GL+ +PDG + SG D + +G+ Sbjct: 235 AFLAALDGSCRTPIAGYATCEGD-NLHFSGLILTPDGQTSHGVEISGNRR--DALILGKK 291 Query: 318 AGHELKSKAGPGFFDG 271 AG E+++KAG FF+G Sbjct: 292 AGEEVRAKAGSNFFEG 307
>HEM3_RHIME (Q92LH7) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 309 Score = 107 bits (268), Expect = 3e-23 Identities = 57/134 (42%), Positives = 83/134 (61%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GL+RL M T +L +E PA AQGAI + R DD++ L++++ T AV+CER Sbjct: 175 GLRRLGMEHVPTELLDPEEFPPAPAQGAICVEARIGDDRINTLLAAIDDPRTHEAVSCER 234 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSGTYSFDDMVAIGQD 319 FL+ LDG+CRTPIA YA D + F G++ +PDG+ ++ G + D +GQ+ Sbjct: 235 GFLATLDGSCRTPIAGYAQSD-GTHIRFAGMILTPDGTTSHQIEIDGRAA--DAERLGQE 291 Query: 318 AGHELKSKAGPGFF 277 AG +++KAGPGFF Sbjct: 292 AGERIRAKAGPGFF 305
>HEM3_RHILO (Q98EI7) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 308 Score = 103 bits (256), Expect = 6e-22 Identities = 59/136 (43%), Positives = 80/136 (58%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GLKRL + AT ++ +D PA QGAIGI R D + + L +++ T A+ACER Sbjct: 174 GLKRLGLEHVATDLMPLDIFPPAPGQGAIGIETRIGDRAVEKMLVAIHDVPTGQALACER 233 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSGTYSFDDMVAIGQD 319 FL+ LDG+CRTPIA +A + GN SF GL+ SPDG+ + G D IG + Sbjct: 234 AFLAALDGSCRTPIAGHA-TIETGNLSFAGLIISPDGTQSHTVELQG--PAQDAARIGDE 290 Query: 318 AGHELKSKAGPGFFDG 271 A +++KAG FFDG Sbjct: 291 AARTVRAKAGEKFFDG 306
>HEM3_STAES (Q8CNY8) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 308 Score = 96.7 bits (239), Expect = 6e-20 Identities = 52/129 (40%), Positives = 76/129 (58%), Gaps = 1/129 (0%) Frame = -2 Query: 678 GLKRLHMAET-ATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACE 502 GLKR+ ++ T+ L D +LPA+ QGA+GI CRS+D ++++ LS +++ D V E Sbjct: 171 GLKRMGWSDNIVTTYLDRDILLPAIGQGALGIECRSDDKELLDLLSKVHNHDVAQCVTAE 230 Query: 501 REFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSGTYSFDDMVAIGQ 322 R FLS +DG+C+ PI YA +D F GL+ SPDG YE + GT D V +G Sbjct: 231 RTFLSEMDGSCQVPIGGYATIAQDNQIEFTGLIMSPDGKERYEHTALGT----DPVKLGI 286 Query: 321 DAGHELKSK 295 + LK + Sbjct: 287 EVSQVLKKQ 295
>HEM3_STAEQ (Q5HNN3) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 308 Score = 96.7 bits (239), Expect = 6e-20 Identities = 52/129 (40%), Positives = 76/129 (58%), Gaps = 1/129 (0%) Frame = -2 Query: 678 GLKRLHMAET-ATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACE 502 GLKR+ ++ T+ L D +LPA+ QGA+GI CRS+D ++++ LS +++ D V E Sbjct: 171 GLKRMGWSDNIVTTYLDRDILLPAIGQGALGIECRSDDKELLDLLSKVHNHDVAQCVTAE 230 Query: 501 REFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSGTYSFDDMVAIGQ 322 R FLS +DG+C+ PI YA +D F GL+ SPDG YE + GT D V +G Sbjct: 231 RTFLSEMDGSCQVPIGGYATIAQDNQIEFTGLIMSPDGKERYEHTALGT----DPVKLGI 286 Query: 321 DAGHELKSK 295 + LK + Sbjct: 287 EVSQVLKKQ 295
>HEM3_STAAU (O34090) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 308 Score = 94.7 bits (234), Expect = 2e-19 Identities = 48/129 (37%), Positives = 79/129 (61%), Gaps = 1/129 (0%) Frame = -2 Query: 678 GLKRLHMAET-ATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACE 502 GL+R+ ++ TS L D +LPA+ QGA+GI CRS+D++++ LS +++++ V E Sbjct: 171 GLRRMGWSDDIVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAE 230 Query: 501 REFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSGTYSFDDMVAIGQ 322 R FL+ +DG+C+ PIA YA F GL+ +PDG +E + +GT D V +G+ Sbjct: 231 RTFLAEMDGSCQVPIAGYATISDQNEIEFTGLIMTPDGKERFEYTMNGT----DPVELGK 286 Query: 321 DAGHELKSK 295 ++LK + Sbjct: 287 TVSNKLKEQ 295
>HEM3_STAAC (Q5HFA2) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 308 Score = 94.7 bits (234), Expect = 2e-19 Identities = 48/129 (37%), Positives = 79/129 (61%), Gaps = 1/129 (0%) Frame = -2 Query: 678 GLKRLHMAET-ATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACE 502 GL+R+ ++ TS L D +LPA+ QGA+GI CRS+D++++ LS +++++ V E Sbjct: 171 GLRRMGWSDDIVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAE 230 Query: 501 REFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSGTYSFDDMVAIGQ 322 R FL+ +DG+C+ PIA YA F GL+ +PDG +E + +GT D V +G+ Sbjct: 231 RTFLAEMDGSCQVPIAGYATISDQNEIEFTGLIMTPDGKERFEYTMNGT----DPVELGK 286 Query: 321 DAGHELKSK 295 ++LK + Sbjct: 287 TVSNKLKEQ 295
>HEM3_STAAW (Q8NW74) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 308 Score = 94.0 bits (232), Expect = 4e-19 Identities = 48/129 (37%), Positives = 79/129 (61%), Gaps = 1/129 (0%) Frame = -2 Query: 678 GLKRLHMAET-ATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACE 502 GL+R+ ++ TS L D +LPA+ QGA+GI CRS+D++++ LS +++++ V E Sbjct: 171 GLRRMGWSDDIVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAE 230 Query: 501 REFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSGTYSFDDMVAIGQ 322 R FL+ +DG+C+ PIA YA F GL+ +PDG +E + +GT D V +G+ Sbjct: 231 RTFLAEMDGSCQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGT----DPVELGK 286 Query: 321 DAGHELKSK 295 ++LK + Sbjct: 287 TVSNKLKEQ 295
>HEM3_STAAS (Q6G8Q5) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 308 Score = 94.0 bits (232), Expect = 4e-19 Identities = 48/129 (37%), Positives = 79/129 (61%), Gaps = 1/129 (0%) Frame = -2 Query: 678 GLKRLHMAET-ATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACE 502 GL+R+ ++ TS L D +LPA+ QGA+GI CRS+D++++ LS +++++ V E Sbjct: 171 GLRRMGWSDDIVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAE 230 Query: 501 REFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSGTYSFDDMVAIGQ 322 R FL+ +DG+C+ PIA YA F GL+ +PDG +E + +GT D V +G+ Sbjct: 231 RTFLAEMDGSCQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGT----DPVELGK 286 Query: 321 DAGHELKSK 295 ++LK + Sbjct: 287 TVSNKLKEQ 295
>HEM3_STAAR (Q6GG35) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 308 Score = 94.0 bits (232), Expect = 4e-19 Identities = 48/129 (37%), Positives = 79/129 (61%), Gaps = 1/129 (0%) Frame = -2 Query: 678 GLKRLHMAET-ATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACE 502 GL+R+ ++ TS L D +LPA+ QGA+GI CRS+D++++ LS +++++ V E Sbjct: 171 GLRRMGWSDDIVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAE 230 Query: 501 REFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSGTYSFDDMVAIGQ 322 R FL+ +DG+C+ PIA YA F GL+ +PDG +E + +GT D V +G+ Sbjct: 231 RTFLAEMDGSCQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGT----DPVELGK 286 Query: 321 DAGHELKSK 295 ++LK + Sbjct: 287 KVSNKLKEQ 295
>HEM3_STAAN (P64341) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 308 Score = 94.0 bits (232), Expect = 4e-19 Identities = 48/129 (37%), Positives = 79/129 (61%), Gaps = 1/129 (0%) Frame = -2 Query: 678 GLKRLHMAET-ATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACE 502 GL+R+ ++ TS L D +LPA+ QGA+GI CRS+D++++ LS +++++ V E Sbjct: 171 GLRRMGWSDDIVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAE 230 Query: 501 REFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSGTYSFDDMVAIGQ 322 R FL+ +DG+C+ PIA YA F GL+ +PDG +E + +GT D V +G+ Sbjct: 231 RTFLAEMDGSCQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGT----DPVELGK 286 Query: 321 DAGHELKSK 295 ++LK + Sbjct: 287 TVSNKLKEQ 295
>HEM3_STAAM (P64340) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 308 Score = 94.0 bits (232), Expect = 4e-19 Identities = 48/129 (37%), Positives = 79/129 (61%), Gaps = 1/129 (0%) Frame = -2 Query: 678 GLKRLHMAET-ATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACE 502 GL+R+ ++ TS L D +LPA+ QGA+GI CRS+D++++ LS +++++ V E Sbjct: 171 GLRRMGWSDDIVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAE 230 Query: 501 REFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSGTYSFDDMVAIGQ 322 R FL+ +DG+C+ PIA YA F GL+ +PDG +E + +GT D V +G+ Sbjct: 231 RTFLAEMDGSCQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGT----DPVELGK 286 Query: 321 DAGHELKSK 295 ++LK + Sbjct: 287 TVSNKLKEQ 295
>HEM3_SHEON (Q8E9H0) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 310 Score = 91.3 bits (225), Expect = 2e-18 Identities = 52/137 (37%), Positives = 76/137 (55%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GL RL ++E S +S +E LPA QGA+GI CR+ND+++ L+ L H +TR V ER Sbjct: 173 GLIRLKLSERIASFISAEESLPANGQGAVGIECRTNDERVKALLAPLEHLETRYRVIAER 232 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSGTYSFDDMVAIGQD 319 + L+G C+ PI A+A D D + RGL+ +PDGS + E +G + + +G Sbjct: 233 AMNTRLEGGCQVPIGAFAEIDGD-EMTLRGLVGNPDGSEIIEGVITGPKT--EATQLGVA 289 Query: 318 AGHELKSKAGPGFFDGL 268 EL SK D + Sbjct: 290 LAEELLSKGAKSILDAV 306
>HEM3_ERWCT (Q6CZG3) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 313 Score = 90.9 bits (224), Expect = 3e-18 Identities = 55/128 (42%), Positives = 71/128 (55%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GLKRL + E LS +E LPAV QGAIGI CR +DD++ + L+ LNH DT V ER Sbjct: 173 GLKRLGLEERIRCALSPEESLPAVGQGAIGIECRLDDDRIRQLLAPLNHTDTAARVLAER 232 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSGTYSFDDMVAIGQD 319 L+G C+ PI +YA + D R L+ +PDGS + R G+ S D IG Sbjct: 233 AMNVRLEGGCQVPIGSYAELEGD-TLWLRALVGAPDGSQMIVGERKGSVS--DAEKIGVA 289 Query: 318 AGHELKSK 295 EL +K Sbjct: 290 LAEELLAK 297
>HEM3_VIBVY (Q7MQC7) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 312 Score = 89.0 bits (219), Expect = 1e-17 Identities = 44/98 (44%), Positives = 60/98 (61%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GLKRL + E S + ++ LPAV QGA+GI CR+ND+++++ L LNH DT V CER Sbjct: 174 GLKRLELEERIRSFIEPEQSLPAVGQGAVGIECRTNDERILKLLEPLNHADTADRVKCER 233 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGS 385 L+G C+ PI +YA + D R L+ PDGS Sbjct: 234 AMNLTLEGGCQVPIGSYALLEGD-EIWLRALVGEPDGS 270
>HEM3_VIBVU (Q8DD85) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 312 Score = 89.0 bits (219), Expect = 1e-17 Identities = 44/98 (44%), Positives = 60/98 (61%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GLKRL + E S + ++ LPAV QGA+GI CR+ND+++++ L LNH DT V CER Sbjct: 174 GLKRLELEERIRSFIEPEQSLPAVGQGAVGIECRTNDERILKLLEPLNHADTADRVKCER 233 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGS 385 L+G C+ PI +YA + D R L+ PDGS Sbjct: 234 AMNLTLEGGCQVPIGSYALLEGD-EIWLRALVGEPDGS 270
>HEM3_CHRVO (Q7P207) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 309 Score = 87.8 bits (216), Expect = 3e-17 Identities = 51/125 (40%), Positives = 69/125 (55%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GLKRL +AE L+ E LPA QGA+GI R++ + L+ LNH DTR A ER Sbjct: 171 GLKRLGLAERIQGELAPSESLPAAGQGALGIEIRADRADLSALLAPLNHPDTRACTAAER 230 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSGTYSFDDMVAIGQD 319 L G+C+ P+ A+A DG + GL+A PDGS+V S SG + D A+G+ Sbjct: 231 ALAKELGGSCQVPLGAFATL-ADGTLTLGGLVAHPDGSVVLTASASGPADYAD--ALGRA 287 Query: 318 AGHEL 304 +L Sbjct: 288 VAKKL 292
>HEM3_PHOLL (Q7MYN1) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 313 Score = 87.4 bits (215), Expect = 4e-17 Identities = 44/106 (41%), Positives = 64/106 (60%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GLKRL + E + L+ ++ LPAV QGA+GI CR +D + L+ LNH DT + V ER Sbjct: 173 GLKRLKLHERIRTPLTAEQSLPAVGQGAVGIECRLDDQQTQTLLAPLNHYDTEVCVLAER 232 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRS 361 + L+G C+ PI +YA +DG R L+ +PDGS++ R+ Sbjct: 233 AMNTRLEGGCQVPIGSYAIW-QDGKIWLRALVGAPDGSVIIRGERT 277
>HEM3_GLOVI (Q7NGF7) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 328 Score = 87.0 bits (214), Expect = 5e-17 Identities = 49/135 (36%), Positives = 70/135 (51%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 G++RL +E + VLS D L AV QGA+GI CR D ++++ L+ LNH T ER Sbjct: 176 GMRRLGWSERISEVLSPDISLHAVGQGALGIECREADGEILDLLTVLNHPPTARRCRAER 235 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSGTYSFDDMVAIGQD 319 L L+G C+ PI Y D G + +G++AS DG + RSG D A+G+ Sbjct: 236 AMLRALEGGCQVPIGVYTELDDSGRLTLQGIVASLDGRNMARACRSG--PGDAPEALGRA 293 Query: 318 AGHELKSKAGPGFFD 274 +LK+ D Sbjct: 294 VAEDLKAAGAQAILD 308
>HEM3_BACSK (Q5WEP5) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 311 Score = 87.0 bits (214), Expect = 5e-17 Identities = 46/108 (42%), Positives = 62/108 (57%), Gaps = 1/108 (0%) Frame = -2 Query: 678 GLKRLHMAETA-TSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACE 502 GLKRL E T L D LPA+ QGA+G+ CR +D + E L+ L+HE+T AV E Sbjct: 171 GLKRLGYGEDVITEYLDKDVCLPAIGQGALGLECRVDDVETTELLAKLHHEETGKAVLAE 230 Query: 501 REFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSG 358 R FL ++G C+ PI YA +DG GL+ SPDG + + + G Sbjct: 231 RAFLKEMNGGCQVPIGGYATVLEDGAVFLTGLVGSPDGKTILKEGKCG 278
>HEM3_PAEMA (O69110) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 324 Score = 86.7 bits (213), Expect = 6e-17 Identities = 55/149 (36%), Positives = 74/149 (49%), Gaps = 19/149 (12%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GL+R+ T+ LS D LPAV QGA+GI CR ND ++ + LS N DT L VA ER Sbjct: 177 GLQRMGWENRVTAYLSADVCLPAVGQGALGIECRENDAELRDVLSLYNDPDTALTVAAER 236 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDG-------------------NCSFRGLLASPDGSIVY 376 FL+VL+G C+ PIAAYA ++ G G++ S DG + Sbjct: 237 RFLAVLNGGCQVPIAAYANLERAGGQAPEEGGRAAASQAPAALRIRLTGMVGSADGRGYF 296 Query: 375 ETSRSGTYSFDDMVAIGQDAGHELKSKAG 289 E G +D VA G+ L ++ G Sbjct: 297 E----GECRREDPVAFGERIAGLLLAQGG 321
>HEM3_GEOKA (Q5KWK6) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 309 Score = 85.9 bits (211), Expect = 1e-16 Identities = 50/136 (36%), Positives = 72/136 (52%), Gaps = 1/136 (0%) Frame = -2 Query: 678 GLKRLHMAETATS-VLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACE 502 GL R+ + S L D +PAV QGA+ + CR +DD++ ++LS LN E T AV E Sbjct: 171 GLARMGWGDDVISDYLPFDVCVPAVGQGALAVECREDDDELRQWLSRLNDEQTERAVRAE 230 Query: 501 REFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSGTYSFDDMVAIGQ 322 R FL ++G C+ PIA YA K+G L+ASPDG +Y+ +G D A+G+ Sbjct: 231 RAFLQQMEGGCQVPIAGYA-EVKEGTVRLTALVASPDGKEMYKEIVTGA----DPEAVGR 285 Query: 321 DAGHELKSKAGPGFFD 274 A L + + Sbjct: 286 QAAAILSEQGAKALIE 301
>HEM3_VIBPA (Q87KI9) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 312 Score = 85.9 bits (211), Expect = 1e-16 Identities = 48/125 (38%), Positives = 69/125 (55%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GLKRL + + S + ++ LPAV QGA+GI CR +D+++++ L LNH+DT V CER Sbjct: 174 GLKRLKLEDRIRSFIEPEQSLPAVGQGAVGIECRVDDERLLKLLEPLNHKDTADRVLCER 233 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSGTYSFDDMVAIGQD 319 L+G C+ PI +YA + D R L+ PDGS + G D A+G Sbjct: 234 AMNLTLEGGCQVPIGSYALLEGD-EIWLRALVGEPDGSEIVRGEVRGHRK--DGEALGIQ 290 Query: 318 AGHEL 304 +EL Sbjct: 291 LANEL 295
>HEM3_LISIN (Q92BF8) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 309 Score = 84.0 bits (206), Expect = 4e-16 Identities = 50/131 (38%), Positives = 73/131 (55%), Gaps = 3/131 (2%) Frame = -2 Query: 678 GLKRLHMAETATSVL---SVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVA 508 GL R+ E + L S + LPAV QGA+ I CR D ++ + L+S++HE+T + V Sbjct: 172 GLARMGWLENTSLKLEDISPELCLPAVGQGALAIECRETDLQICDMLASIHHEETGICVE 231 Query: 507 CEREFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSGTYSFDDMVAI 328 ER FL L+G C PIA +A + D + F+GL+ + DGSI+ E+ R+G I Sbjct: 232 AERVFLKKLNGGCEIPIAGFATKTGD-SVHFKGLVGNADGSIILESERTGA----SPAEI 286 Query: 327 GQDAGHELKSK 295 G EL S+ Sbjct: 287 GNQVAEELLSE 297
>HEM3_PROMI (Q59684) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 313 Score = 84.0 bits (206), Expect = 4e-16 Identities = 50/128 (39%), Positives = 65/128 (50%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GLKRL + E S LS ++ LPAV QGA+GI CR +D L++LNH DT V ER Sbjct: 173 GLKRLKLTERIRSSLSAEQSLPAVGQGAVGIECRLDDHDTQALLAALNHADTATCVKAER 232 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSGTYSFDDMVAIGQD 319 + L+G C+ PI +YA D R L+ +PDG + R S +D G Sbjct: 233 AMNTRLEGGCQVPIGSYAIWQND-KIWLRALVGAPDGKTILRGER--LVSPEDAEQAGIS 289 Query: 318 AGHELKSK 295 EL K Sbjct: 290 LAEELLDK 297
>HEM3_ECOLI (P06983) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 313 Score = 83.6 bits (205), Expect = 5e-16 Identities = 45/107 (42%), Positives = 61/107 (57%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GLKRL + + L + LPAV QGA+GI CR +D + E L++LNH +T L V ER Sbjct: 173 GLKRLGLESRIRAALPPEISLPAVGQGAVGIECRLDDSRTRELLAALNHHETALRVTAER 232 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSG 358 + L+G C+ PI +YA DG R L+ +PDGS + R G Sbjct: 233 AMNTRLEGGCQVPIGSYA-ELIDGEIWLRALVGAPDGSQIIRGERRG 278
>HEM3_BACHD (Q9K8G0) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 311 Score = 83.2 bits (204), Expect = 7e-16 Identities = 45/126 (35%), Positives = 69/126 (54%), Gaps = 1/126 (0%) Frame = -2 Query: 678 GLKRLHMA-ETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACE 502 GL+R+ + E T L D +PAV QGA+GI CR++DD+++E L ++N + T V E Sbjct: 171 GLERMGWSNEIVTEYLDPDLCVPAVGQGALGIECRADDDEVLEMLKTINDDTTAKTVLAE 230 Query: 501 REFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSGTYSFDDMVAIGQ 322 R FL ++G C+ PIA YA +G L+ +PDG +++ G D V +G+ Sbjct: 231 RTFLHRMEGGCQVPIAGYATLTDEGEIELTALVGTPDGEQIFKEILRG----KDPVQLGE 286 Query: 321 DAGHEL 304 L Sbjct: 287 TMAQAL 292
>HEM3_IDILO (Q5QUS3) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 313 Score = 83.2 bits (204), Expect = 7e-16 Identities = 47/110 (42%), Positives = 61/110 (55%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GL RL + + TS + V++ LPA QGA+GI CRS+DD+M L+ L ++TR V ER Sbjct: 172 GLIRLELGDRITSFIPVEQSLPANGQGALGIECRSDDDEMKALLAPLQCQETRTRVLAER 231 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSGTYS 349 LDG C+ PI AYA + D RGL+ PDG V G S Sbjct: 232 AMNRGLDGGCQVPIGAYAELEGD-EVYLRGLVGEPDGGKVLRDEVRGPAS 280
>HEM3_ECO57 (Q8XAP3) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 313 Score = 83.2 bits (204), Expect = 7e-16 Identities = 45/107 (42%), Positives = 61/107 (57%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GLKRL + + L + LPAV QGA+GI CR +D + E L++LNH +T L V ER Sbjct: 173 GLKRLGLESRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAER 232 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSG 358 + L+G C+ PI +YA DG R L+ +PDGS + R G Sbjct: 233 AMNTRLEGGCQVPIGSYA-ELIDGEIWLRALVGAPDGSQIIRGERRG 278
>HEM3_VIBCH (Q9KVM1) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 311 Score = 82.8 bits (203), Expect = 9e-16 Identities = 43/98 (43%), Positives = 55/98 (56%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GLKRL + S + ++ LPAV QGA+GI CR ND ++ L+ LNH DT V CER Sbjct: 173 GLKRLELESRIRSFIEPEQSLPAVGQGAVGIECRVNDQRVRALLAPLNHADTADRVRCER 232 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGS 385 L G C+ PI +YA + D R L+ PDGS Sbjct: 233 AMNLTLQGGCQVPIGSYALLEGD-TIWLRALVGEPDGS 269
>HEM3_YERPE (P46355) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 313 Score = 82.8 bits (203), Expect = 9e-16 Identities = 45/107 (42%), Positives = 59/107 (55%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GLKRL + +S +E LPAV QGA+GI CR +DD + L+ LNH T L V ER Sbjct: 173 GLKRLGLENRIRYAMSAEESLPAVGQGAVGIECRLDDDHTRQLLAPLNHRHTELRVCAER 232 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSG 358 L+G C+ PI +YA + D R L+ +PDGS + R G Sbjct: 233 AMNIRLEGGCQVPIGSYAELEGD-TLWLRALVGAPDGSQMIRGERRG 278
>HEM3_ECOL6 (Q8FBP1) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 313 Score = 82.8 bits (203), Expect = 9e-16 Identities = 45/107 (42%), Positives = 61/107 (57%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GLKRL + + L + LPAV QGA+GI CR +D + E L++LNH +T L V ER Sbjct: 173 GLKRLGLESRIRAALPPEISLPAVGQGAVGIECRLDDARTRELLAALNHHETALRVTAER 232 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSG 358 + L+G C+ PI +YA DG R L+ +PDGS + R G Sbjct: 233 AMNTRLEGGCQVPIGSYA-ELIDGEIWLRALVGAPDGSQIIRGERRG 278
>HEM3_YERPS (Q66G00) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 313 Score = 82.4 bits (202), Expect = 1e-15 Identities = 45/107 (42%), Positives = 59/107 (55%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GLKRL + +S +E LPAV QGA+GI CR +DD + L+ LNH T L V ER Sbjct: 173 GLKRLGLETRIRYAMSAEESLPAVGQGAVGIECRLDDDHTRQLLAPLNHRHTELRVCAER 232 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSG 358 L+G C+ PI +YA + D R L+ +PDGS + R G Sbjct: 233 AMNIRLEGGCQVPIGSYAELEGD-TLWLRALVGAPDGSQMIRGERRG 278
>HEM3_PSESM (Q88B91) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 313 Score = 82.0 bits (201), Expect = 1e-15 Identities = 44/100 (44%), Positives = 60/100 (60%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GL RL + TS +SVD+ LPA QGA+GI CRS D ++ L+ L+HEDT + V ER Sbjct: 173 GLIRLGFEDRITSAISVDDSLPAGGQGAVGIECRSVDAEIHALLAPLHHEDTAVRVIAER 232 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIV 379 L+G C+ PIA YA + D + RGL+ P G ++ Sbjct: 233 SLNKHLNGGCQVPIACYAVLEGD-DVWLRGLVGDPSGRVL 271
>HEM3_SALTY (P0A1Q8) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 313 Score = 81.6 bits (200), Expect = 2e-15 Identities = 44/108 (40%), Positives = 60/108 (55%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GLKRL + + L D LPAV QGA+GI CR +D + L+ LNH T L V ER Sbjct: 173 GLKRLGLESRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAER 232 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSGT 355 + L+G C+ PI +YA +G R L+ +PDGS++ R G+ Sbjct: 233 AMNTRLEGGCQVPIGSYA-EIINGEIWLRALVGAPDGSVMVRGERRGS 279
>HEM3_SALTI (P0A1Q9) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 313 Score = 81.6 bits (200), Expect = 2e-15 Identities = 44/108 (40%), Positives = 60/108 (55%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GLKRL + + L D LPAV QGA+GI CR +D + L+ LNH T L V ER Sbjct: 173 GLKRLGLESRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAER 232 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSGT 355 + L+G C+ PI +YA +G R L+ +PDGS++ R G+ Sbjct: 233 AMNTRLEGGCQVPIGSYA-EIINGEIWLRALVGAPDGSVMVRGERRGS 279
>HEM3_GEOSL (Q747I1) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 318 Score = 81.6 bits (200), Expect = 2e-15 Identities = 49/131 (37%), Positives = 68/131 (51%), Gaps = 6/131 (4%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GLKRL + T L VD LPA+ QGA+G+ CR +D + E + NH DT AV ER Sbjct: 172 GLKRLGFTDVVTEYLPVDLSLPAIGQGALGLECRLDDQAVRETIDFFNHPDTAHAVRAER 231 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSGTYSFDDMVAIG-- 325 L +G C+ PIAA+ D + + G +AS DG+ + S SG + + + I Sbjct: 232 ALLWRCEGGCQVPIAAHGQVSGD-SLTLTGFIASVDGTRSVKESISGPVTDCEKLGIALA 290 Query: 324 ----QDAGHEL 304 D GHE+ Sbjct: 291 EKLLADGGHEI 301
>HEM3_LISMO (Q8Y6X5) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 309 Score = 80.9 bits (198), Expect = 3e-15 Identities = 44/110 (40%), Positives = 65/110 (59%), Gaps = 3/110 (2%) Frame = -2 Query: 678 GLKRLHMAETATSVLS---VDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVA 508 GL R+ E T L + LPAV QGA+ I CR +D ++ + L+S++HE+T + V Sbjct: 172 GLARMGWLENTTLKLEDIPPEVCLPAVGQGALAIECRESDQQIRDMLTSIHHEETGICVE 231 Query: 507 CEREFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSG 358 ER FL L+G C PIA +A R + F+GL+ + DGSI+ E+ + G Sbjct: 232 AERVFLKKLNGGCEIPIAGFATRANE-FVQFKGLVGNADGSIILESEQVG 280
>HEM3_BACSU (P16616) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 313 Score = 80.5 bits (197), Expect = 4e-15 Identities = 39/108 (36%), Positives = 61/108 (56%), Gaps = 1/108 (0%) Frame = -2 Query: 678 GLKRLHMAE-TATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACE 502 GL R+ + T L + LPAV QGA+ I CR +D++++ S E T+ V E Sbjct: 171 GLSRMGWKQDVVTEFLEPERCLPAVGQGALAIECRESDEELLALFSQFTDEYTKRTVLAE 230 Query: 501 REFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSG 358 R FL+ ++G C+ PIA Y+ + GL+ASPDG I+++ + +G Sbjct: 231 RAFLNAMEGGCQVPIAGYSVLNGQDEIEMTGLVASPDGKIIFKETVTG 278
>HEM3_BUCAI (P57651) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 314 Score = 80.5 bits (197), Expect = 4e-15 Identities = 42/110 (38%), Positives = 63/110 (57%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GL RL + T ++ + LP+ QGAIGI R +D K++ +LS LNH +T + + ER Sbjct: 173 GLNRLRLKNRITQIIPAELSLPSCGQGAIGIQSRLHDKKVLFFLSRLNHINTFIEINAER 232 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSGTYS 349 F L+ C+ PI +YA K+ RGL+ SP+G I+ + R G Y+ Sbjct: 233 AFCRKLESGCQIPIGSYAILKKN-KIWLRGLVGSPNGKIILKGERIGCYN 281
>HEM3_METCA (Q602K3) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 322 Score = 80.5 bits (197), Expect = 4e-15 Identities = 44/107 (41%), Positives = 57/107 (53%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GLKRL E L+ ++ LPA+ QGAIG+ CRS D + L L+H T V ER Sbjct: 185 GLKRLGFQERIAETLTPEQCLPAIGQGAIGVECRSTDTRTNALLVPLHHPPTAWCVLAER 244 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSG 358 LDG C+ PIA +A + D S RGL+ +PDGS + G Sbjct: 245 AMNRRLDGGCQVPIAGFAQLEGD-TLSLRGLVGNPDGSGIIRAEAVG 290
>HEM3_SHIFL (Q83PH4) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 313 Score = 80.1 bits (196), Expect = 6e-15 Identities = 44/107 (41%), Positives = 60/107 (56%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GLKRL + + L + LPAV QGA+GI CR +D + E L++LNH +T L V ER Sbjct: 173 GLKRLGLESRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAER 232 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSG 358 + L+G C+ PI +YA DG L+ +PDGS + R G Sbjct: 233 AMNTRLEGGCQVPIGSYA-ELIDGEIWLCALVGAPDGSQIIRGERRG 278
>HEM3_PSEAE (Q60169) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 313 Score = 80.1 bits (196), Expect = 6e-15 Identities = 44/98 (44%), Positives = 55/98 (56%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GL RL S +SVD+ LPA QGA+GI CR+ D + L L+H DT L V ER Sbjct: 173 GLIRLGFESRIRSSISVDDSLPAGGQGAVGIECRTADSDLHALLEPLHHTDTALRVTAER 232 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGS 385 L+G C+ PIA YA R+ D RGL+ PDG+ Sbjct: 233 ALNKRLNGGCQVPIACYAIREGD-QLWLRGLVGQPDGT 269
>HEM3_COXBU (Q83A37) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 307 Score = 79.3 bits (194), Expect = 1e-14 Identities = 47/130 (36%), Positives = 67/130 (51%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GLKRL + E +PA+ QGAIG+ CRS+D +M L SL+H +TRL V ER Sbjct: 172 GLKRLGLENRIHYYFDPHEFIPAIGQGAIGVECRSDDHEMQTLLKSLDHRETRLCVTAER 231 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSGTYSFDDMVAIGQD 319 L G+C TPIAA+A K+ S +L DG ++ + G + ++ IG Sbjct: 232 AVNEKLGGDCFTPIAAHAI-IKNDQLSLFAMLGKIDGRVIIRATEIG--NSEEAKRIGFK 288 Query: 318 AGHELKSKAG 289 +L + G Sbjct: 289 VASQLLEQGG 298
>HEM3_LISMF (Q71ZB2) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 309 Score = 79.0 bits (193), Expect = 1e-14 Identities = 43/110 (39%), Positives = 65/110 (59%), Gaps = 3/110 (2%) Frame = -2 Query: 678 GLKRLHMAETATSVLS---VDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVA 508 GL R+ E T L + LPAV QGA+ I CR +D ++ + L+S++HE+T + V Sbjct: 172 GLARMGWLENTTLKLEDIPPELCLPAVGQGALAIECRESDQQIRDMLTSIHHEETGICVE 231 Query: 507 CEREFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSG 358 ER FL L+G C PIA +A R + F+GL+ + DGSI+ + ++G Sbjct: 232 AERVFLKKLNGGCEIPIAGFATRANE-VVHFKGLVGNADGSIILASEQAG 280
>HEM3_NITEU (Q82WS2) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 308 Score = 78.6 bits (192), Expect = 2e-14 Identities = 46/127 (36%), Positives = 67/127 (52%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GLKRL + + +L + LPAV QGA+GI CR ND M+E++ L+H T V ER Sbjct: 174 GLKRLELGYRISMLLPPELSLPAVGQGALGIECRDNDPDMVEWMKPLHHAATACCVEAER 233 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSGTYSFDDMVAIGQD 319 +L G+C+ P+ +A +D + RG +A+PDGS + G + V GQ Sbjct: 234 AMSRMLGGSCQVPLGGFAEIFED-VLTLRGFVATPDGSRMIADKLCGKPESGEQV--GQQ 290 Query: 318 AGHELKS 298 LK+ Sbjct: 291 LAQNLKA 297
>HEM3_DESVH (Q72AV0) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 315 Score = 78.2 bits (191), Expect = 2e-14 Identities = 44/108 (40%), Positives = 59/108 (54%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GLKRL +A VL+ LPAV QGA+GI R + + + L+ L+H TR+ V ER Sbjct: 172 GLKRLGLAAPHHEVLAPPRFLPAVGQGALGIEFREDRADLRDMLAFLDHRPTRIRVEAER 231 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSGT 355 FL+ L+G C+ PIA +A D N GL+A G V + GT Sbjct: 232 GFLAGLEGGCQVPIAGHAVMTGDDNFRIEGLVADLKGERVIRRTLEGT 279
>HEM3_BLOFL (Q7VRM4) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 311 Score = 77.4 bits (189), Expect = 4e-14 Identities = 45/125 (36%), Positives = 65/125 (52%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GL RL + + + + E+LPA+ QG I I CR ND + LS L H++T L + ER Sbjct: 174 GLTRLKLTKYIQTYIDPSELLPAMGQGVIAIECRINDINTISLLSPLYHKETSLCIKSER 233 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSGTYSFDDMVAIGQD 319 + L+ CR PIA+YA ++ R L+ PDGSI+ T G S D +G + Sbjct: 234 AVTTYLESYCRLPIASYA-EIQNNQIWLRALIGLPDGSIIIRT--EGIASLDKAEELGLN 290 Query: 318 AGHEL 304 +L Sbjct: 291 LAKDL 295
>HEM3_NEIMB (Q9K0P6) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 311 Score = 76.3 bits (186), Expect = 8e-14 Identities = 43/125 (34%), Positives = 65/125 (52%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GL+RL + +LS + LPA QGA+GI ++ + + E L LNH T V ER Sbjct: 173 GLQRLKLDGRIRMILSESDSLPAAGQGALGIEIAAHREDLYEVLKPLNHGVTNACVTAER 232 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSGTYSFDDMVAIGQD 319 L G+C+ P+AAY +++G + RGL+ PDGS+V + D A+G+ Sbjct: 233 ALARALGGSCQVPLAAYC-TEENGLLTLRGLVGHPDGSVVLRADAQAPAEYAD--ALGRA 289 Query: 318 AGHEL 304 +L Sbjct: 290 VAKKL 294
>HEM3_NEIMA (Q9JVS4) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 311 Score = 76.3 bits (186), Expect = 8e-14 Identities = 43/125 (34%), Positives = 65/125 (52%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GL+RL + +LS + LPA QGA+GI ++ + + E L LNH T V ER Sbjct: 173 GLQRLKLDGRIRMILSESDSLPAAGQGALGIEIAAHREDLYEVLKPLNHGVTNACVTAER 232 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSGTYSFDDMVAIGQD 319 L G+C+ P+AAY +++G + RGL+ PDGS+V + D A+G+ Sbjct: 233 ALARALGGSCQVPLAAYC-TEENGLLTLRGLVGHPDGSVVLRADAQAPAEYAD--ALGRA 289 Query: 318 AGHEL 304 +L Sbjct: 290 VAKKL 294
>HEM32_STRCO (Q9KY00) Porphobilinogen deaminase 2 (EC 2.5.1.61) (PBG 2)| (Hydroxymethylbilane synthase 2) (HMBS 2) (Pre-uroporphyrinogen synthase 2) Length = 313 Score = 76.3 bits (186), Expect = 8e-14 Identities = 35/99 (35%), Positives = 55/99 (55%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GL+R+ + + VLS + M+P + G + + CR D ++E +S+L T ER Sbjct: 177 GLERIGRTDVISEVLSTETMMPPIGAGILALQCREGDRALIEAVSALGDPRTHREATAER 236 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSI 382 FL VL G+C +PIA +A D+ G S R + +PDG + Sbjct: 237 MFLHVLQGHCNSPIAGHAQVDRSGELSLRACVFTPDGKV 275
>HEM3_MANSM (Q65VX7) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 310 Score = 75.5 bits (184), Expect = 1e-13 Identities = 40/98 (40%), Positives = 56/98 (57%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GL RL MAE S + D LPA QGA+GI CR +D+ + L+ L H++T + V ER Sbjct: 174 GLIRLGMAERIASFIETDISLPAAGQGAVGIECRVDDELVQSLLAPLAHQETTICVLAER 233 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGS 385 + L G C+ PI +A + K+G R L+ + DGS Sbjct: 234 AMNNRLQGGCQVPIGGFA-QVKNGEVFLRALVGATDGS 270
>HEM3_PSEPK (Q88RE5) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 313 Score = 75.5 bits (184), Expect = 1e-13 Identities = 43/97 (44%), Positives = 55/97 (56%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GL RL + TS +SVD+ LPA QGA+GI CRS D ++ L+ L+H DT V ER Sbjct: 173 GLIRLGFEDRITSTISVDDSLPAGGQGAVGIECRSADVEIHALLAPLHHVDTADRVIAER 232 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDG 388 L+G C+ PIA YA + D RGL+ P G Sbjct: 233 ALNKRLNGGCQVPIACYAVLEGD-QLWLRGLVGQPSG 268
>HEM3_MYCTU (P64336) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 309 Score = 74.7 bits (182), Expect = 2e-13 Identities = 45/116 (38%), Positives = 62/116 (53%), Gaps = 8/116 (6%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GL RL + T L +MLPA AQGA+ + CR+ D +++ L+ L+ DTR AV ER Sbjct: 165 GLARLGRLDDVTETLEPVQMLPAPAQGALAVECRAGDSRLVAVLAELDDADTRAAVTAER 224 Query: 498 EFLSVLDGNCRTPIAAYA----YRDKDG----NCSFRGLLASPDGSIVYETSRSGT 355 L+ L+ C P+ A A D+DG S RG +A+ DGS V S G+ Sbjct: 225 ALLADLEAGCSAPVGAIAEVVESIDEDGRVFEELSLRGCVAALDGSDVIRASGIGS 280
>HEM3_MYCBO (P64337) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 309 Score = 74.7 bits (182), Expect = 2e-13 Identities = 45/116 (38%), Positives = 62/116 (53%), Gaps = 8/116 (6%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GL RL + T L +MLPA AQGA+ + CR+ D +++ L+ L+ DTR AV ER Sbjct: 165 GLARLGRLDDVTETLEPVQMLPAPAQGALAVECRAGDSRLVAVLAELDDADTRAAVTAER 224 Query: 498 EFLSVLDGNCRTPIAAYA----YRDKDG----NCSFRGLLASPDGSIVYETSRSGT 355 L+ L+ C P+ A A D+DG S RG +A+ DGS V S G+ Sbjct: 225 ALLADLEAGCSAPVGAIAEVVESIDEDGRVFEELSLRGCVAALDGSDVIRASGIGS 280
>HEM31_STRAW (Q82E76) Porphobilinogen deaminase 1 (EC 2.5.1.61) (PBG 1)| (Hydroxymethylbilane synthase 1) (HMBS 1) (Pre-uroporphyrinogen synthase 1) Length = 324 Score = 74.7 bits (182), Expect = 2e-13 Identities = 44/138 (31%), Positives = 71/138 (51%), Gaps = 6/138 (4%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GL R+ + T L VD +LPA QGA+ I C +++ ++ L+ L+ TR AV ER Sbjct: 180 GLHRIGRIDEVTEFLPVDTVLPAPGQGALAIECAADNADLIAALAELDDPFTRAAVTAER 239 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDG----NCSFRGLLASPDGSIVYETSRSGTY--SFDDM 337 L+ L+ C P+ A A DG RG++ + DGS + + S +G + D Sbjct: 240 SLLAALEAGCSAPVGALADLLADGQIVTEMRLRGVVGTTDGSTLVQLSTTGPVPETHDQA 299 Query: 336 VAIGQDAGHELKSKAGPG 283 +A+G++ E+ +K G Sbjct: 300 MALGRELAAEMLAKGAAG 317
>HEM3_RALSO (Q8XWW3) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 334 Score = 73.9 bits (180), Expect = 4e-13 Identities = 39/97 (40%), Positives = 56/97 (57%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GLKRL ++E +V++ + LPA QGA+GI R + + +L+ L+H T LAV ER Sbjct: 189 GLKRLGLSERIRAVIAPETSLPAAGQGALGIESRVDRHDVQAWLAPLHHAPTALAVTAER 248 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDG 388 L G+C+ P+AA+A G R +ASPDG Sbjct: 249 AVSRQLGGSCQVPLAAFAQWTDAGALRLRAFVASPDG 285
>HEM3_MYCPA (Q73SS0) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 315 Score = 73.2 bits (178), Expect = 7e-13 Identities = 45/116 (38%), Positives = 60/116 (51%), Gaps = 8/116 (6%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GL RL T L +MLPA AQGA+ + CR+ D ++ L+ L+ DTR +V ER Sbjct: 165 GLARLGRLGDVTETLEPVQMLPAPAQGALAVECRAGDSRLAAVLAELDDADTRASVTAER 224 Query: 498 EFLSVLDGNCRTPIAAYA----YRDKDG----NCSFRGLLASPDGSIVYETSRSGT 355 L+ L+ C P+ A A D+DG S RG +A+ DGS V S GT Sbjct: 225 ALLAELEAGCSAPVGAIAEVVESIDEDGRIFEELSLRGCVAALDGSDVIRASGIGT 280
>HEM3_DEBHA (Q6BM23) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 361 Score = 72.8 bits (177), Expect = 9e-13 Identities = 44/132 (33%), Positives = 63/132 (47%), Gaps = 2/132 (1%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GL R+ + + T+ L EM AV QGA+GI R D+KM++ L ++ T ER Sbjct: 196 GLIRIGLGDRITAHLDAPEMYYAVGQGALGIEIRKGDEKMLQLLKTIEDLPTTYCCLAER 255 Query: 498 EFLSVLDGNCRTPIAAYA-YRDKDGNCSFRGLLASPDGSIVYETSRSGTY-SFDDMVAIG 325 + L+G C PI + Y + S + ++ SPDG E G + DD AIG Sbjct: 256 SLMRHLEGGCSVPIGVQSHYNESTNELSLKAIIVSPDGIHFVEDEYKGVVNNKDDADAIG 315 Query: 324 QDAGHELKSKAG 289 G L +K G Sbjct: 316 IKVGDLLSAKGG 327
>HEM3_CAMJE (Q9PHW9) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 307 Score = 72.4 bits (176), Expect = 1e-12 Identities = 46/130 (35%), Positives = 70/130 (53%), Gaps = 2/130 (1%) Frame = -2 Query: 678 GLKRLHMAETATSV--LSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVAC 505 G+KRL++ + V S DE++PA +QGA+GI ND+K++E L LN E+ + + Sbjct: 169 GIKRLNLDKQVNFVYEFSKDELIPAASQGALGIES-INDEKILELLKCLNDENALIETSI 227 Query: 504 EREFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSGTYSFDDMVAIG 325 EREF++ L+G C+ PI A D C R +L PDGS + + R +D G Sbjct: 228 EREFIATLEGGCQVPIGINAELLGDEIC-VRAVLGLPDGSEILKDKR--MIKKNDFKGFG 284 Query: 324 QDAGHELKSK 295 + E +K Sbjct: 285 ESLAKEFIAK 294
>HEM32_STRAW (Q82P95) Porphobilinogen deaminase 2 (EC 2.5.1.61) (PBG 2)| (Hydroxymethylbilane synthase 2) (HMBS 2) (Pre-uroporphyrinogen synthase 2) Length = 314 Score = 72.4 bits (176), Expect = 1e-12 Identities = 35/100 (35%), Positives = 53/100 (53%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GL+R+ + T VL + M+P + G + + CR D ++E +S L T ER Sbjct: 178 GLERIGREDVITEVLEPETMMPPIGAGILALQCREGDTGLIETISELGDPGTHREATAER 237 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIV 379 FL VL G+C +PIA YA +++G S R + + DG V Sbjct: 238 MFLHVLQGHCNSPIAGYARTERNGELSLRASVFTLDGKTV 277
>HEM3_OCEIH (Q8CXC0) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 309 Score = 72.0 bits (175), Expect = 2e-12 Identities = 43/136 (31%), Positives = 70/136 (51%), Gaps = 1/136 (0%) Frame = -2 Query: 678 GLKRLHMAETA-TSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACE 502 GLKR+ ++E T L + +PAV QGA+ I R +D+++ + ++ T V+ E Sbjct: 171 GLKRVGLSEELITEYLEPEVCVPAVGQGALAIESREDDEELTNIVKKIHDAYTAKTVSAE 230 Query: 501 REFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSGTYSFDDMVAIGQ 322 R FL +L+G C+ PI YAY D D L+ PDG+ + + + GT + +G+ Sbjct: 231 RTFLHLLEGGCQVPIGGYAYLDGD-EVVLTALVGDPDGTTILKETVRGT----EPTEVGK 285 Query: 321 DAGHELKSKAGPGFFD 274 +A L S+ D Sbjct: 286 EAAELLISQGAKEIVD 301
>HEM31_STRCO (Q9WX16) Porphobilinogen deaminase 1 (EC 2.5.1.61) (PBG 1)| (Hydroxymethylbilane synthase 1) (HMBS 1) (Pre-uroporphyrinogen synthase 1) Length = 319 Score = 71.6 bits (174), Expect = 2e-12 Identities = 42/138 (30%), Positives = 71/138 (51%), Gaps = 6/138 (4%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GL R+ + T LSVD +LPA QGA+ + C +++ ++ L+ L+ TR AV ER Sbjct: 175 GLNRVGRIDEVTDFLSVDTVLPAPGQGALAVECAADNASLIAALAELDDPFTRAAVTAER 234 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDG----NCSFRGLLASPDGSIVYETSRSGTY--SFDDM 337 L+ L+ C P+ A A DG RG++ + DGS + + S +G + + Sbjct: 235 SLLAALEAGCSAPVGALADLLADGQTVKEMRLRGVVGTTDGSTLVQLSTTGPVPETHEAA 294 Query: 336 VAIGQDAGHELKSKAGPG 283 +A+G + E+ ++ G Sbjct: 295 LALGGELAAEMLAQGAAG 312
>HEM3_BORPE (Q7VVU9) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 314 Score = 71.6 bits (174), Expect = 2e-12 Identities = 45/125 (36%), Positives = 63/125 (50%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GL+RL +A ++L D+ LPA QGA+GI + L+ L T V ER Sbjct: 174 GLERLGLAARIRALLEPDDSLPAAGQGALGIEILQGRADVRAMLAPLGDAATLACVTAER 233 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSGTYSFDDMVAIGQD 319 +L G+C+ P+AAYA D D + R L+A+PDG + R G D AIG+ Sbjct: 234 AVSRMLGGSCQVPLAAYARIDGD-ELALRALVAAPDGRRIVRAERRGPR--DQAQAIGES 290 Query: 318 AGHEL 304 A +L Sbjct: 291 AARDL 295
>HEM3_MYCLE (Q49808) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 315 Score = 71.6 bits (174), Expect = 2e-12 Identities = 44/116 (37%), Positives = 60/116 (51%), Gaps = 8/116 (6%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GL RL + T L +M+PA AQGAI + CR+ D +++ L++L+ DTR AV ER Sbjct: 165 GLARLGRLDEVTETLDPVQMVPAPAQGAIAVECRAGDSRLVAVLAALDDADTRAAVTAER 224 Query: 498 EFLSVLDGNCRTPIAAYA--YRDKDG------NCSFRGLLASPDGSIVYETSRSGT 355 L+ L+ C P+ A A DG S RG +A+ DGS V S T Sbjct: 225 VLLAELEAGCSAPVGAIAQVVESIDGEGRVFEELSLRGCVAALDGSDVIRASGIST 280
>HEM3_ACIAD (Q6FFA9) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 311 Score = 71.6 bits (174), Expect = 2e-12 Identities = 37/107 (34%), Positives = 60/107 (56%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GLKRL + ++ + LPAV QGA+G+ CR+ND K+++ ++ L H+ T V ER Sbjct: 176 GLKRLGLISRIRHSINAEISLPAVGQGALGLECRANDKKILDLIAPLAHQPTSACVRAER 235 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSG 358 F + L+G C+ PIA +A ++ + G + S DG + + G Sbjct: 236 AFNAYLEGGCQVPIAGFATLTQE-CLTLEGRVGSVDGKTLLKDHVEG 281
>HEM3_SYNY3 (P73660) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 320 Score = 71.2 bits (173), Expect = 3e-12 Identities = 43/128 (33%), Positives = 67/128 (52%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GL+RL MA ++ + L AV QGA+GI CR D +++ L L E++R ER Sbjct: 180 GLERLDMANRIDQLIPPEISLHAVGQGALGIECREGDQEILSLLKVLEDENSRDRCLAER 239 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSGTYSFDDMVAIGQD 319 FL L+G C+ PI + D D N + G++AS DG + + + S + +GQD Sbjct: 240 AFLRQLEGGCQVPIGVNTHLDGD-NLTLTGMVASLDGQRLIKDTLSAPRK--EAEKLGQD 296 Query: 318 AGHELKSK 295 +L+ + Sbjct: 297 LALKLREQ 304
>HEM3_BACHK (Q6HD62) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 309 Score = 71.2 bits (173), Expect = 3e-12 Identities = 45/126 (35%), Positives = 65/126 (51%), Gaps = 1/126 (0%) Frame = -2 Query: 678 GLKRLHMA-ETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACE 502 GL+R+ E T L +PAV QGA+ I CR +D +++ L+ +N T VA E Sbjct: 171 GLQRMGWDDEVITEHLDETLCVPAVGQGALAIECREDDKDLLQLLAHINDAVTERTVAAE 230 Query: 501 REFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSGTYSFDDMVAIGQ 322 R FL L+G C+ PIA YA ++ L+ S DGSI+ + + GT D +G Sbjct: 231 RVFLHKLEGGCQVPIAGYATLTENDAIELTALVGSMDGSILLKETVVGT----DPEKVGL 286 Query: 321 DAGHEL 304 +A L Sbjct: 287 EAADRL 292
>HEM3_BACCZ (Q633Y0) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 309 Score = 70.9 bits (172), Expect = 3e-12 Identities = 44/126 (34%), Positives = 65/126 (51%), Gaps = 1/126 (0%) Frame = -2 Query: 678 GLKRLHMA-ETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACE 502 GL+R+ E T L +PAV QGA+ I CR +D +++ L+ +N T VA E Sbjct: 171 GLQRMGWDDEVITEHLDETLCVPAVGQGALAIECREDDTDLLQLLAHINDAVTERTVAAE 230 Query: 501 REFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSGTYSFDDMVAIGQ 322 R FL L+G C+ PIA YA ++ L+ S DGS++ + + GT D +G Sbjct: 231 RVFLHKLEGGCQVPIAGYATLTENDAIELTALVGSMDGSVLLKETVVGT----DPEKVGL 286 Query: 321 DAGHEL 304 +A L Sbjct: 287 EAADRL 292
>HEM3_SYNEL (Q8DIE4) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 320 Score = 70.5 bits (171), Expect = 4e-12 Identities = 43/128 (33%), Positives = 65/128 (50%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GL+RL + + VL L AV QGA+GI CR+ D ++ + +L H +T ER Sbjct: 179 GLRRLGFGDRISQVLPATVSLYAVGQGALGIECRAEDADILALVKTLEHPETTARCLAER 238 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSGTYSFDDMVAIGQD 319 FL L+G C+ PI + + +G + GL+AS DG + + S +G VA ++ Sbjct: 239 AFLRQLEGGCQVPIGVHTVIE-NGQLTLTGLVASLDGQRLVKDSLTGD------VATAEE 291 Query: 318 AGHELKSK 295 G L K Sbjct: 292 LGTRLALK 299
>HEM3_NOCFA (Q5YP70) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 346 Score = 70.5 bits (171), Expect = 4e-12 Identities = 45/115 (39%), Positives = 57/115 (49%), Gaps = 8/115 (6%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GL R+ T L +MLPA AQGA+ + CRS D ++E L+ L+ TR AV ER Sbjct: 173 GLSRIGRTAVITEALEPVQMLPAPAQGALAVECRSEDAALIEALAELDDAATRAAVVAER 232 Query: 498 EFLSVLDGNCRTPIAAYA----YRDKDG----NCSFRGLLASPDGSIVYETSRSG 358 L+ L+ C P+ A A D DG S RG A+ DGS V S G Sbjct: 233 ALLAELEAGCTAPVGALAEVVESLDDDGRIVEELSLRGCAAAVDGSEVLRASVVG 287
>HEM3_BACC1 (Q72ZW2) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 309 Score = 70.5 bits (171), Expect = 4e-12 Identities = 44/126 (34%), Positives = 65/126 (51%), Gaps = 1/126 (0%) Frame = -2 Query: 678 GLKRLHMA-ETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACE 502 GL+R+ E T L +PAV QGA+ I CR +D +++ L+ +N T VA E Sbjct: 171 GLQRMGWDNEVITEHLDETLCVPAVGQGALAIECREDDKDLLQLLAHMNDGVTEKTVAAE 230 Query: 501 REFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSGTYSFDDMVAIGQ 322 R FL L+G C+ PIA YA ++ L+ S DGS++ + + GT D +G Sbjct: 231 RVFLHKLEGGCQVPIAGYATLTENDAIELTALVGSMDGSVLLKETVVGT----DPEKVGL 286 Query: 321 DAGHEL 304 +A L Sbjct: 287 EAADRL 292
>HEM3_BACAN (Q81LC7) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 309 Score = 70.5 bits (171), Expect = 4e-12 Identities = 44/126 (34%), Positives = 65/126 (51%), Gaps = 1/126 (0%) Frame = -2 Query: 678 GLKRLHMA-ETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACE 502 GL+R+ E T L +PAV QGA+ I CR +D +++ L+ +N T VA E Sbjct: 171 GLQRMGWDNEVITEHLDETLCVPAVGQGALAIECREDDKDLLQLLAHINDAVTEKTVAAE 230 Query: 501 REFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSGTYSFDDMVAIGQ 322 R FL L+G C+ PIA YA ++ L+ S DGS++ + + GT D +G Sbjct: 231 RVFLHKLEGGCQVPIAGYATITENDAIELTALVGSMDGSVLLKETVVGT----DPEKVGL 286 Query: 321 DAGHEL 304 +A L Sbjct: 287 EAADRL 292
>HEM3_ANASP (Q8YVU6) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 323 Score = 69.7 bits (169), Expect = 8e-12 Identities = 44/119 (36%), Positives = 66/119 (55%), Gaps = 1/119 (0%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GL+RL M + +L + L AV QGA+GI CR++D +++ L ++ H +TR ER Sbjct: 182 GLQRLGMGDRVHQILPKEISLHAVGQGALGIECRADDAELITVLKAIEHPETRDRCLAER 241 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGN-CSFRGLLASPDGSIVYETSRSGTYSFDDMVAIG 325 FL L+G C+ PI + +GN G++AS DG + + + SG S D AIG Sbjct: 242 SFLRSLEGGCQVPIGVNT--EINGNELILTGVVASVDGQNLVKDTVSGNAS--DAEAIG 296
>HEM3_RHOBA (Q7UPN0) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 337 Score = 68.6 bits (166), Expect = 2e-11 Identities = 38/100 (38%), Positives = 55/100 (55%), Gaps = 3/100 (3%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 G+ RL M + + +DEM+PA QGA+GI RS+D M+ +++LN RLA ER Sbjct: 187 GILRLEMTDLPHRLFPLDEMIPAPGQGALGIEVRSDDAGAMDAIANLNDAAARLAATAER 246 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGN---CSFRGLLASPDG 388 + LS L G C PIA +A + + R ++ S DG Sbjct: 247 KVLSELHGGCLAPIACHAKLETSNHGTELCLRAIVMSADG 286
>HEM3_BACCR (Q817R0) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 309 Score = 68.6 bits (166), Expect = 2e-11 Identities = 34/88 (38%), Positives = 51/88 (57%) Frame = -2 Query: 618 LPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACEREFLSVLDGNCRTPIAAYAYR 439 +PAV QGA+ I CR +D +++ L+ +N T VA ER FL L+G C+ PIA YA Sbjct: 192 VPAVGQGALAIECREDDKDLLQLLAHINDTITERTVAAERVFLHKLEGGCQVPIAGYATL 251 Query: 438 DKDGNCSFRGLLASPDGSIVYETSRSGT 355 ++ L+ S DGS++ + + GT Sbjct: 252 TENDAIELTALVGSMDGSVLLKETVVGT 279
>HEM3_BORPA (Q7W785) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 314 Score = 68.6 bits (166), Expect = 2e-11 Identities = 44/125 (35%), Positives = 62/125 (49%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GL+RL +A ++L + LPA QGA+GI + L+ L T V ER Sbjct: 174 GLERLGLAARIRALLEPADSLPAAGQGALGIEILQGRADVRAMLAPLGDAATLACVTAER 233 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSGTYSFDDMVAIGQD 319 +L G+C+ P+AAYA D D + R L+A+PDG + R G D AIG+ Sbjct: 234 AVSRMLGGSCQVPLAAYARIDGD-ELALRALVAAPDGRRIVRAERRGPR--DQAQAIGES 290 Query: 318 AGHEL 304 A +L Sbjct: 291 AARDL 295
>HEM3_BORBR (Q7WKM1) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 314 Score = 68.6 bits (166), Expect = 2e-11 Identities = 44/125 (35%), Positives = 62/125 (49%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GL+RL +A ++L + LPA QGA+GI + L+ L T V ER Sbjct: 174 GLERLGLAARIRALLEPADSLPAAGQGALGIEILQGRADVRAMLAPLGDAATLACVTAER 233 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSGTYSFDDMVAIGQD 319 +L G+C+ P+AAYA D D + R L+A+PDG + R G D AIG+ Sbjct: 234 AVSRMLGGSCQVPLAAYARIDGD-ELALRALVAAPDGRRIVRAERRGPR--DQAQAIGES 290 Query: 318 AGHEL 304 A +L Sbjct: 291 AARDL 295
>HEM3_CANAL (O94048) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 340 Score = 67.8 bits (164), Expect = 3e-11 Identities = 41/137 (29%), Positives = 64/137 (46%), Gaps = 2/137 (1%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GL RL + TS L D+M AV QGA+GI R DD + L + + ER Sbjct: 191 GLIRLGLGHRITSYL--DDMYYAVGQGALGIEIRKGDDNIKSILKKIEDPIATICCLAER 248 Query: 498 EFLSVLDGNCRTPIAAYA-YRDKDGNCSFRGLLASPDGSIVYETSRSGTYSFD-DMVAIG 325 + L+G C P+ ++ Y + + +G++ SPDG++ E + D D +G Sbjct: 249 SLMRYLEGGCSVPLGVHSDYNESKQELTLKGIIVSPDGTVSIEDEVIKRITCDEDCEQVG 308 Query: 324 QDAGHELKSKAGPGFFD 274 + G +LK+K D Sbjct: 309 IELGDKLKAKGAKEILD 325
>HEM3_CLOAB (Q97MU4) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 291 Score = 67.4 bits (163), Expect = 4e-11 Identities = 32/78 (41%), Positives = 51/78 (65%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GLKRL+M T SV+EM+PAV QGA+G+ + ++K + L+++++R+ V ER Sbjct: 169 GLKRLNMENIITDYFSVEEMIPAVGQGALGVEIK-KENKNRDLFRKLDNKNSRMCVEAER 227 Query: 498 EFLSVLDGNCRTPIAAYA 445 F+ L+G+C + I AYA Sbjct: 228 SFMRTLNGDCHSTIGAYA 245
>HEM3_CORGL (Q8NT90) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 302 Score = 67.4 bits (163), Expect = 4e-11 Identities = 33/81 (40%), Positives = 49/81 (60%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GL R+ M + AT V D ++PA AQGA+ I CR++D + + L+ L H DT ++ ER Sbjct: 165 GLTRVGMQDRATEVFDADIIMPAPAQGALAIECRADDTETVRALNMLMHADTFVSAVAER 224 Query: 498 EFLSVLDGNCRTPIAAYAYRD 436 L+ L+ C P+AA+A D Sbjct: 225 TVLNRLEAGCTAPVAAHATLD 245
>HEM3_FUSNN (Q8RFP5) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 298 Score = 67.0 bits (162), Expect = 5e-11 Identities = 33/83 (39%), Positives = 48/83 (57%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GLKR +A+ T L+ + PA AQG + I CR ND+++ E L S+++E V ER Sbjct: 173 GLKRTGLADKITEYLNGEVFPPAPAQGVLYIQCRENDEEIKEILKSIHNEAIAKIVEIER 232 Query: 498 EFLSVLDGNCRTPIAAYAYRDKD 430 EF + DG C TP+ Y+ + D Sbjct: 233 EFSKIFDGGCHTPMGCYSQVNGD 255
>HEM3_COREF (Q8FSF7) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 299 Score = 66.6 bits (161), Expect = 6e-11 Identities = 33/81 (40%), Positives = 47/81 (58%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GL R+ M + AT V D ++PA AQGA+ I CR D+ ++ L+ L H DT + ER Sbjct: 165 GLSRVGMQDRATQVFDPDMLMPAPAQGALAIECRVEDEDIITGLNMLMHADTYVTAVAER 224 Query: 498 EFLSVLDGNCRTPIAAYAYRD 436 L+ L+ C P+AA+A D Sbjct: 225 TVLNRLEAGCTAPVAAHATLD 245
>HEM3_THET2 (Q72H57) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 301 Score = 66.6 bits (161), Expect = 6e-11 Identities = 40/130 (30%), Positives = 58/130 (44%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GL RL + L E+LPA QGA+ + R DD E +L+H + V ER Sbjct: 166 GLIRLDLRNRIDEFLDPGEVLPAPGQGALALEVREGDDLAEELCYALHHPPSYHRVRAER 225 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSGTYSFDDMVAIGQD 319 FL L C P+ A A+ ++DG G+L +PDG G S + +G D Sbjct: 226 AFLRGLGAGCLAPVGALAHVEEDGTLRLEGVLLTPDGKSFIRAEIEGDVS--EAEELGLD 283 Query: 318 AGHELKSKAG 289 ++ + G Sbjct: 284 LARDVLEQGG 293
>HEM3_BURPS (Q63W73) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 329 Score = 65.9 bits (159), Expect = 1e-10 Identities = 44/140 (31%), Positives = 72/140 (51%), Gaps = 3/140 (2%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GLKRL +A ++L VD+ LPA QGA+GI + + +L+ L+ + LAV ER Sbjct: 181 GLKRLGLAARIRALLDVDDSLPAAGQGALGIEIAARRADVAAWLAPLHDHASALAVEAER 240 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIV---YETSRSGTYSFDDMVAI 328 L G+C P+AA+A + G G +++ DG+ V + +R+ T + D +A+ Sbjct: 241 AVSRALGGSCEVPLAAHAVW-RGGELHLTGSVSTTDGARVLAAHAHARAATAA--DALAL 297 Query: 327 GQDAGHELKSKAGPGFFDGL 268 G+ L+ + D L Sbjct: 298 GRRVSDALERQGARAIVDAL 317
>HEM3_BURMA (Q62LC0) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 329 Score = 65.9 bits (159), Expect = 1e-10 Identities = 44/140 (31%), Positives = 72/140 (51%), Gaps = 3/140 (2%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GLKRL +A ++L VD+ LPA QGA+GI + + +L+ L+ + LAV ER Sbjct: 181 GLKRLGLAARIRALLDVDDSLPAAGQGALGIEIAARRADVAAWLAPLHDHASALAVEAER 240 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIV---YETSRSGTYSFDDMVAI 328 L G+C P+AA+A + G G +++ DG+ V + +R+ T + D +A+ Sbjct: 241 AVSRALGGSCEVPLAAHAVW-RGGELHLTGSVSTTDGARVLAAHAHARAATAA--DALAL 297 Query: 327 GQDAGHELKSKAGPGFFDGL 268 G+ L+ + D L Sbjct: 298 GRRVSDALERQGARAIVDAL 317
>HEM3_LEGPH (Q5ZRY6) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 309 Score = 65.5 bits (158), Expect = 1e-10 Identities = 37/116 (31%), Positives = 61/116 (52%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GL+R+ +A T ++ D MLP AQGA+ I CR++D ++ E + LN + L V ER Sbjct: 173 GLERMGLAHHITQLIPDDIMLPTCAQGALCIECRTDDLEIQELVHGLNDPISALCVHTER 232 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSGTYSFDDMVA 331 + L GNC P A Y ++ R + + DGS + + + G + +++A Sbjct: 233 RVNAKLGGNCHIPFAVYCTITEEKLLLLRAKVLNMDGSQMIDDEQQGKIAEAEVIA 288
>HEM3_XANAC (Q8PPR3) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 304 Score = 65.5 bits (158), Expect = 1e-10 Identities = 42/129 (32%), Positives = 68/129 (52%), Gaps = 1/129 (0%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GL+RL + ++ L E LPA AQGA+ + CR +D ++ L+ L+ TR+ V ER Sbjct: 171 GLQRLGLEARISARLDAPEWLPAPAQGAVAVECRGDDARIHSLLAVLDAGRTRVCVEAER 230 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLAS-PDGSIVYETSRSGTYSFDDMVAIGQ 322 L G+C P+AA+A R + + +G++ S DG +++ + S DD A+G+ Sbjct: 231 AMNRALHGSCHVPVAAFA-RWEGQDLFLQGMVGSASDGRLIHADAHG---SADDTEALGR 286 Query: 321 DAGHELKSK 295 L K Sbjct: 287 RVAQGLFDK 295
>HEM3_RICCN (Q92HR5) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 351 Score = 65.5 bits (158), Expect = 1e-10 Identities = 33/79 (41%), Positives = 46/79 (58%), Gaps = 1/79 (1%) Frame = -2 Query: 678 GLKRLHMAETA-TSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACE 502 GLKRL + ++ +MLP + QG I + R +D+ M+E + +NH T + E Sbjct: 172 GLKRLEVFNPEYCHLIEYSQMLPCIGQGVIAVEIRKDDNAMLEICNQINHLPTFELIKPE 231 Query: 501 REFLSVLDGNCRTPIAAYA 445 R FL LD NCRTPIAAY+ Sbjct: 232 RAFLEYLDANCRTPIAAYS 250
>HEM3_LEGPL (Q5WT65) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 309 Score = 64.7 bits (156), Expect = 2e-10 Identities = 37/116 (31%), Positives = 59/116 (50%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GL+R+ +A T ++ D MLP AQGA+ I CR++D ++ E + LN + L V ER Sbjct: 173 GLERMGLAHHITQLIPDDIMLPTCAQGALCIECRTDDLEIQELIYGLNDPISALCVHTER 232 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSGTYSFDDMVA 331 + L GNC P A Y + R + + DGS + + + G +++A Sbjct: 233 RVNAKLGGNCHIPFAVYCTITAENLLLLRAKVLNLDGSQMIDDEQQGKIEEAEIIA 288
>HEM3_HELHP (Q7VFE9) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 321 Score = 64.7 bits (156), Expect = 2e-10 Identities = 37/117 (31%), Positives = 65/117 (55%), Gaps = 1/117 (0%) Frame = -2 Query: 678 GLKRLHM-AETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACE 502 G+ RL + + ++ +D M+PA+ QGA+GI R D + ++ LN + + L V+ E Sbjct: 177 GVNRLKINTQDVRYIVPLDFMIPAMGQGALGIEMR-KDSIFFDRIAVLNDKQSALCVSAE 235 Query: 501 REFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSGTYSFDDMVA 331 R F+ L+G C+ PI YA + + + + ++ PDGS V + S + + DD+ A Sbjct: 236 RAFVRTLEGGCQVPIGVYA-QFSNNKLTLQAIVGLPDGSEVLQDSVEDSINIDDINA 291
>HEM3_LEGPA (Q5X1F2) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 309 Score = 64.3 bits (155), Expect = 3e-10 Identities = 37/116 (31%), Positives = 59/116 (50%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GL+R+ +A T ++ D MLP AQGA+ I CR++D ++ E + LN + L V ER Sbjct: 173 GLERMGLAHHITQLIPDDIMLPTCAQGALCIECRTDDLEIQELIHGLNDPISALCVHTER 232 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSGTYSFDDMVA 331 + L GNC P A Y + R + + DGS + + + G +++A Sbjct: 233 RVNAKLGGNCHIPFAVYCTITAEKLLLLRAKVLNLDGSQMIDDEQQGKIEEAEIIA 288
>HEM3_XANCP (Q8P536) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 304 Score = 64.3 bits (155), Expect = 3e-10 Identities = 37/115 (32%), Positives = 63/115 (54%), Gaps = 1/115 (0%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GL+RL + T+ L E LPA AQGA+ + CR +D ++ + L+ L+ TR V ER Sbjct: 171 GLQRLGLEARITARLDAPEWLPAPAQGAVAVECRGDDARIHDLLAVLDAGRTRACVEAER 230 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLAS-PDGSIVYETSRSGTYSFDDM 337 L G+C P+AA+A R + + +G++ S DG +++ + + +D+ Sbjct: 231 AMNRALHGSCHVPVAAFA-RWEGEDLFLQGMVGSASDGRLIHAEAHGSPDATEDL 284
>HEM3_AQUAE (O66621) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 304 Score = 64.3 bits (155), Expect = 3e-10 Identities = 38/130 (29%), Positives = 66/130 (50%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 G+KR+ T VL ++ +PAV QG++ I R D ++ E + LN+E++ L ER Sbjct: 169 GVKRMGYESEITEVL--EDFIPAVGQGSLAIEIREGDKRIEELIKPLNNEESFLCAIAER 226 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSGTYSFDDMVAIGQD 319 FL L+G C+ P+ A+A + ++G + ++ + E R G + ++ +G Sbjct: 227 TFLRRLEGGCQVPVGAFA-KIENGTLKMKAFISDIEAERYIEGYREG--NPEEAEKLGLS 283 Query: 318 AGHELKSKAG 289 EL K G Sbjct: 284 LAEELLKKGG 293
>HEM3_RICPR (Q9ZD77) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 299 Score = 63.2 bits (152), Expect = 7e-10 Identities = 33/79 (41%), Positives = 45/79 (56%), Gaps = 1/79 (1%) Frame = -2 Query: 678 GLKRLHMA-ETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACE 502 GLKRL++ + ++ +MLP + QG I + R +D+ M S +NH T + E Sbjct: 172 GLKRLNVFNQKYCHLIEYSKMLPCIGQGVIAVEIRKDDNAMFNICSQINHLPTFELIKPE 231 Query: 501 REFLSVLDGNCRTPIAAYA 445 R FL LD NC TPIAAYA Sbjct: 232 RAFLEYLDANCSTPIAAYA 250
>HEM3_CHLVI (P28464) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 311 Score = 62.4 bits (150), Expect = 1e-09 Identities = 34/97 (35%), Positives = 51/97 (52%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 G+ RL ++ T +L + MLPAV QGA+GI R++D + E + LN ++T + ER Sbjct: 171 GVYRLEFSDRITEILPHETMLPAVGQGALGIETRTDDAETREIVRVLNDDNTEMCCRAER 230 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDG 388 L L G C+ PI ++ DG + S DG Sbjct: 231 ALLRHLQGGCQIPIGSFG-SYIDGTLKLLAFVGSVDG 266
>HEM3_PASMU (Q9CK24) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 309 Score = 62.0 bits (149), Expect = 2e-09 Identities = 38/100 (38%), Positives = 53/100 (53%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GL RL + TS++ V + LPAV QGA+GI CR + ++ L+ L +T V ER Sbjct: 174 GLIRLGQQQRITSLIDVTQCLPAVGQGAVGIECR-QEAEIELLLAPLADPETTACVLAER 232 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIV 379 L G C+ PIA YA + +G R L+ DGS + Sbjct: 233 AMNRHLQGGCQVPIAGYAIIE-EGQLFLRALVGEVDGSSI 271
>HEM3_CORDI (Q6NJK0) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 294 Score = 61.6 bits (148), Expect = 2e-09 Identities = 34/100 (34%), Positives = 53/100 (53%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GL R+ + AT V + LPA AQGA+ + CR++D E + S+ E ++ ER Sbjct: 163 GLTRVGRGDEATQVFDPQDFLPAPAQGALAVECRADDAYAREAIDSICDEQAQVCAVTER 222 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIV 379 L+ L+ C P+AA+A + DG + + + DGS V Sbjct: 223 VVLNRLEAGCTAPVAAHATLN-DGTLTLTAAVIALDGSKV 261
>HEM3_PROMP (Q7V2I1) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 316 Score = 61.2 bits (147), Expect = 3e-09 Identities = 37/126 (29%), Positives = 63/126 (50%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GLKRL ++ + L AV QGA+GI C+S+D ++++ +S L + + ER Sbjct: 176 GLKRLGFESRVHQIIPNEISLHAVGQGALGIECKSDDKEVLKIISVLEDKVSSQRCLAER 235 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSGTYSFDDMVAIGQD 319 FL L+G C+ PI + D + G++AS DG + + G + + +G+ Sbjct: 236 SFLRELEGGCQVPIGVNSSIQND-EIALIGMVASIDGKRLIKNESIGNIKYPE--EVGKK 292 Query: 318 AGHELK 301 +LK Sbjct: 293 LAEKLK 298
>HEM3_SYNPX (Q7U5C2) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 317 Score = 60.8 bits (146), Expect = 4e-09 Identities = 40/126 (31%), Positives = 61/126 (48%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GL+RL ++ D L AV QGA+GI C + +++E + L H T ER Sbjct: 176 GLERLGFGNRIHQIIPGDISLHAVGQGALGIECVEDKPEVLEIIKVLEHTTTSRRCLAER 235 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSGTYSFDDMVAIGQD 319 FL L+G C+ PI + + + + G++AS DG + SG S D +IG + Sbjct: 236 AFLRELEGGCQVPIGVNSQINNE-ELTLTGMVASLDGKRLIRDEASG--SAADPESIGIE 292 Query: 318 AGHELK 301 +LK Sbjct: 293 LAGKLK 298
>HEM3_FRATT (Q5NI31) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 300 Score = 60.5 bits (145), Expect = 5e-09 Identities = 38/125 (30%), Positives = 57/125 (45%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GL RL + E T + V+ LPAV QG + I D+ ++E + LN ++ ER Sbjct: 170 GLIRLELVERITQFIPVEISLPAVGQGIVVIEALERDNDLLEKIQKLNCRESSRVATAER 229 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSGTYSFDDMVAIGQD 319 F L G C I AYA D + + ++AS DG + + G DD +G+ Sbjct: 230 AFNQELKGGCHVAIGAYAELD-NNQITLMAMVASSDGKKILKRKMIG----DDPTKLGKL 284 Query: 318 AGHEL 304 E+ Sbjct: 285 LAQEM 289
>HEM3_ASHGO (Q75DY0) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 326 Score = 60.5 bits (145), Expect = 5e-09 Identities = 38/122 (31%), Positives = 60/122 (49%), Gaps = 3/122 (2%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GL RL + T ML AV QGA+GI R+ D+++ L+ + ++ + ER Sbjct: 182 GLVRLGLESRITQRFDSTIMLHAVGQGALGIETRTGDERLQAILAKVADRNSTICCLAER 241 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGN-CSFRGLLASPDGSIVYETSRSGTYSFD--DMVAI 328 + L+G C PI Y+ D++ + + GL+ S DG+ E + S D D +A Sbjct: 242 SLMRTLEGGCSVPIGVYSTFDEETSMLTLDGLVVSVDGADAAEATVSYKIKSDKEDAIAC 301 Query: 327 GQ 322 GQ Sbjct: 302 GQ 303
>HEM3_CHLTE (Q8KCJ4) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 312 Score = 60.5 bits (145), Expect = 5e-09 Identities = 29/77 (37%), Positives = 44/77 (57%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 G+ RL ++ + +L D MLPAV QGA+GI R++D + +E + +N +T + ER Sbjct: 172 GVYRLEFSDRISEILPHDVMLPAVGQGALGIETRTDDAETIEIVRVMNDSNTEICCRAER 231 Query: 498 EFLSVLDGNCRTPIAAY 448 L L G C+ PI Y Sbjct: 232 ALLRHLQGGCQIPIGCY 248
>HEM3_PROMA (Q7VD89) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 315 Score = 60.1 bits (144), Expect = 6e-09 Identities = 36/128 (28%), Positives = 66/128 (51%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GL RL ++ + L AV QGA+GI C + +++++ + L H+++ L ER Sbjct: 176 GLTRLGFGNRIHQLIPSEISLHAVGQGALGIECVKDKEEILQIIKVLEHKESSLRCLAER 235 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSGTYSFDDMVAIGQD 319 FL L+G C+ PI + + + G++AS DG + +++G+ + IG + Sbjct: 236 AFLKELEGGCQVPIGVNS-KIQGQELILTGMVASLDGKQLIRDTKTGSSMHPE--TIGIE 292 Query: 318 AGHELKSK 295 + LKS+ Sbjct: 293 LANTLKSQ 300
>HEM3_PROMM (Q7V697) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 317 Score = 60.1 bits (144), Expect = 6e-09 Identities = 39/128 (30%), Positives = 61/128 (47%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GL RL + ++ + L AV QGA+GI C +++E + +L H+ T ER Sbjct: 176 GLTRLGFGDRIHQLIPSEISLHAVGQGALGIECVEGHPEVLEAIKALEHKPTAQRCLAER 235 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSGTYSFDDMVAIGQD 319 L L+G C+ PI + R + G++AS DG + + G D AIG++ Sbjct: 236 ALLRELEGGCQVPIGVNS-RIEANELLLTGMVASLDGKRLIRDQQRG--PIDRCEAIGKE 292 Query: 318 AGHELKSK 295 LKS+ Sbjct: 293 LAETLKSQ 300
>HEM3_YARLI (Q6C097) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 338 Score = 59.7 bits (143), Expect = 8e-09 Identities = 35/138 (25%), Positives = 65/138 (47%), Gaps = 1/138 (0%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GLKRL + + T L +ML AV QGA+G+ R D+K + L ++ +++ L ER Sbjct: 196 GLKRLDLGDRITGYLQKPDMLHAVGQGALGLEIRQGDEKTKKILEAIYDKESTLCCLAER 255 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSGTYSFD-DMVAIGQ 322 + L+G C PI + ++G + ++ S +G+ E ++ + + +G+ Sbjct: 256 AVMRTLEGGCSVPIGVET-KYENGKLTLDAIVVSVEGTEFVECTQVRAVEENWEAEQLGK 314 Query: 321 DAGHELKSKAGPGFFDGL 268 D +L D + Sbjct: 315 DVAEQLVKDGAKKILDAI 332
>HEM3_EUGGR (P13446) Porphobilinogen deaminase, chloroplast precursor (EC| 2.5.1.61) (PBG) (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 480 Score = 59.7 bits (143), Expect = 8e-09 Identities = 35/101 (34%), Positives = 53/101 (52%), Gaps = 4/101 (3%) Frame = -2 Query: 678 GLKRLHMAETA----TSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAV 511 GLKRL ++ T+++ + M PA QGA+ I R+ND ++ L L+H + V Sbjct: 322 GLKRLGFSDRVLPGETNIIDPNVMCPAAGQGALSIELRTNDPEIAALLEPLHHIPDAVTV 381 Query: 510 ACEREFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDG 388 ACER L+G C+ PI+ +A + KDG + S G Sbjct: 382 ACERAMNRRLNGGCQVPISGFA-QLKDGQLRMEARVGSVTG 421
>HEM3_CLOPE (Q8XKG4) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 291 Score = 58.9 bits (141), Expect = 1e-08 Identities = 31/84 (36%), Positives = 46/84 (54%), Gaps = 1/84 (1%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GLKRL M + + LPA+ QGA+GI C + +Y +L+ ++ R V ER Sbjct: 169 GLKRLGMEDVISDYFDPKVFLPAIGQGALGIECLKGGE-FNDYFKALDSKEVRTTVEAER 227 Query: 498 EFLSVLDGNCRTPIAAYA-YRDKD 430 F+ VL+G C + I AY+ +D D Sbjct: 228 SFMKVLNGGCHSLIGAYSEVKDND 251
>HEM3_MOUSE (P22907) Porphobilinogen deaminase (EC 2.5.1.61)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) (PBG-D) Length = 361 Score = 58.5 bits (140), Expect = 2e-08 Identities = 38/124 (30%), Positives = 60/124 (48%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GL+R+ +L +E + AV QGA+ + R+ D +++ +S L+ +T L ER Sbjct: 192 GLQRMGWQNRVGQILHPEECMYAVGQGALAVEVRAKDQDILDLVSVLHDPETLLRCIAER 251 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSGTYSFDDMVAIGQD 319 FL L+G C P+A + KDG G + S DGS + + T V + Q+ Sbjct: 252 AFLRHLEGGCSVPVAVHTV-IKDGQLYLTGGVWSLDGSDSMQETMQATI----QVPVQQE 306 Query: 318 AGHE 307 G E Sbjct: 307 DGPE 310
>HEM3_HUMAN (P08397) Porphobilinogen deaminase (EC 2.5.1.61)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) (PBG-D) Length = 361 Score = 58.5 bits (140), Expect = 2e-08 Identities = 33/98 (33%), Positives = 51/98 (52%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GL+R+ +L +E + AV QGA+G+ R+ D +++ + L+ +T L ER Sbjct: 192 GLQRMGWHNRVGQILHPEECMYAVGQGALGVEVRAKDQDILDLVGVLHDPETLLRCIAER 251 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGS 385 FL L+G C P+A + KDG G + S DGS Sbjct: 252 AFLRHLEGGCSVPVAVHTAM-KDGQLYLTGGVWSLDGS 288
>HEM3_METJA (Q57989) Probable porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 292 Score = 58.5 bits (140), Expect = 2e-08 Identities = 27/64 (42%), Positives = 37/64 (57%) Frame = -2 Query: 624 EMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACEREFLSVLDGNCRTPIAAYA 445 ++LPA AQG I +AC+ +D++M L +NHE T L CER L+ G C P A A Sbjct: 182 DILPAPAQGIIAVACKRDDEEMKSILKEINHERTYLESLCERTALNEFGGGCSVPFGALA 241 Query: 444 YRDK 433 D+ Sbjct: 242 VYDE 245
>HEM3_RAT (P19356) Porphobilinogen deaminase (EC 2.5.1.61)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) (PBG-D) Length = 361 Score = 57.8 bits (138), Expect = 3e-08 Identities = 37/124 (29%), Positives = 59/124 (47%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GL+R+ +L +E + AV QGA+ + R+ D +++ + L+ +T L ER Sbjct: 192 GLQRMGWQNRVGQILHPEECMYAVGQGALAVEVRAKDQDILDLVGVLHDPETLLRCIAER 251 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSGTYSFDDMVAIGQD 319 FL L+G C P+A + KDG G + S DGS + + T V + Q+ Sbjct: 252 AFLRHLEGGCSVPVAVHTVM-KDGQLYLTGGVWSLDGSDSMQETMQATI----QVPVQQE 306 Query: 318 AGHE 307 G E Sbjct: 307 DGPE 310
>HEM3_KLULA (Q6CT60) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 327 Score = 57.4 bits (137), Expect = 4e-08 Identities = 37/140 (26%), Positives = 61/140 (43%), Gaps = 3/140 (2%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GL R + T + D M AV QGA+GI R +D+KM + L + T + ER Sbjct: 182 GLMRSGLDSRITQRFNADTMCYAVGQGALGIEIRKDDEKMKKILKEICDPSTTICCLAER 241 Query: 498 EFLSVLDGNCRTPIAAYA-YRDKDGNCSFRGLLASPDGSIVYETSRSGTYS--FDDMVAI 328 L L+G C PI + Y + + +G++ + +G+ E T S +D + Sbjct: 242 SLLRTLEGGCSVPIGVVSNYDESTKVLTLKGIVINVEGTEWVEIEHKVTISNEREDSINC 301 Query: 327 GQDAGHELKSKAGPGFFDGL 268 G++ +L D + Sbjct: 302 GKELAAKLTQNGAKEILDSI 321
>HEM3_RICTY (Q68WR3) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 299 Score = 57.0 bits (136), Expect = 5e-08 Identities = 30/79 (37%), Positives = 43/79 (54%), Gaps = 1/79 (1%) Frame = -2 Query: 678 GLKRLH-MAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACE 502 GLKRL+ + ++ ++LP V QG I + R +D+ M + +NH T + E Sbjct: 172 GLKRLNAFNKKYCHLIEYSQILPCVGQGVIAVEIRKDDNAMFNICNQINHIPTFELIKPE 231 Query: 501 REFLSVLDGNCRTPIAAYA 445 R FL LD NC TPI AY+ Sbjct: 232 RAFLEHLDANCSTPIGAYS 250
>HEM3_WOLSU (Q7M8L2) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 311 Score = 55.8 bits (133), Expect = 1e-07 Identities = 32/100 (32%), Positives = 51/100 (51%), Gaps = 2/100 (2%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDE--MLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVAC 505 G+ RL + + V+ +D M+PA+ Q A+GI C+ + L + R+ Sbjct: 171 GVNRLDLWKEVNYVIPIDTEMMIPAMGQAALGIECKEGSEAF-RLTQILEDKKARIETTA 229 Query: 504 EREFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGS 385 EREF+ VL+G C+ PI A AY + + + + PDGS Sbjct: 230 EREFVRVLEGGCQVPIGANAYLEGE-TLHLKVAVGLPDGS 268
>HEM3_XYLFA (Q9PCX7) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 305 Score = 55.5 bits (132), Expect = 1e-07 Identities = 35/101 (34%), Positives = 52/101 (51%), Gaps = 1/101 (0%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GL+RL + + T+ L+ E LPA QGAI + + D ++ L+ L+ TR V ER Sbjct: 171 GLRRLGLEQRMTARLAPPEWLPAPGQGAIAVESLTEDARIGTLLAGLDDLPTRQCVVAER 230 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLAS-PDGSIV 379 L G+C P+ AYA + G +GL+ DG +V Sbjct: 231 TMNRALHGSCHVPVGAYASYEV-GGMRLQGLVGCVADGRLV 270
>HEM3_HELPJ (Q9ZMJ7) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 306 Score = 55.5 bits (132), Expect = 1e-07 Identities = 38/115 (33%), Positives = 57/115 (49%), Gaps = 3/115 (2%) Frame = -2 Query: 678 GLKRLHMAETA-TSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACE 502 GL RL++ SV EM+P++ QGA+G+ N + L LN+E++ E Sbjct: 170 GLCRLNVQGAKYRKAFSVKEMIPSMGQGALGVEMLKNHKHFIT-LQKLNNEESAFCCHLE 228 Query: 501 REFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSG--TYSFD 343 REF+ L+G C+ PI +A D R +L P+G V + G T +FD Sbjct: 229 REFIKGLNGGCQIPIGVHANLMGD-EVKIRAVLGLPNGKEVIAKEKQGDKTKAFD 282
>HEM3_XYLFT (Q87CC9) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 305 Score = 55.1 bits (131), Expect = 2e-07 Identities = 35/101 (34%), Positives = 52/101 (51%), Gaps = 1/101 (0%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GL+RL + + T+ L+ E LPA QGAI + + D ++ L+ L+ TR V ER Sbjct: 171 GLRRLGLEQRMTARLAPPEWLPAPGQGAIAVESLTEDARIGTLLAGLDDLPTRKCVIAER 230 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLAS-PDGSIV 379 L G+C P+ AYA + G +GL+ DG +V Sbjct: 231 TMNRALHGSCHVPVGAYASYEV-GGMRLQGLVGCVADGRLV 270
>HEM3_PROAC (Q6AB05) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 334 Score = 55.1 bits (131), Expect = 2e-07 Identities = 32/81 (39%), Positives = 43/81 (53%), Gaps = 3/81 (3%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDD---KMMEYLSSLNHEDTRLAVA 508 GL RL + T L +LPA AQGA+ + CR+ D K+ + L+ ++ TRLA Sbjct: 178 GLARLGHSGAVTEFLDPSVVLPAPAQGALAVECRTADSRHGKLAKALARIDDRRTRLAAT 237 Query: 507 CEREFLSVLDGNCRTPIAAYA 445 ER LS L+ C PI A A Sbjct: 238 AERAVLSHLEAGCAAPIGALA 258
>HEM3_CANGA (Q6FNR4) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 329 Score = 55.1 bits (131), Expect = 2e-07 Identities = 30/103 (29%), Positives = 51/103 (49%), Gaps = 1/103 (0%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GL R+ + + T L D M AV QGA+GI R D K+++ L + ++ + ER Sbjct: 182 GLVRMGLEDRITQRLHSDIMYHAVGQGALGIEIRQGDKKILQILDEIADLESTVCCLAER 241 Query: 498 EFLSVLDGNCRTPIAA-YAYRDKDGNCSFRGLLASPDGSIVYE 373 + L+G C PI +Y K +G++ + +G++ E Sbjct: 242 SLMRTLEGGCSVPIGVESSYDHKTKKLLLKGIVVNVEGTMAIE 284
>HEM3_CLOJO (Q59293) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 291 Score = 54.7 bits (130), Expect = 3e-07 Identities = 29/78 (37%), Positives = 44/78 (56%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 G+KRL + SVDE+LPA +QG I + R ++ ++L + E++ ER Sbjct: 166 GIKRLGLESRIGRYFSVDEILPAASQGIIAVQGRVGEN--FDFLKLFHSEESLCISLAER 223 Query: 498 EFLSVLDGNCRTPIAAYA 445 F+ ++G C TPIAAYA Sbjct: 224 TFVREMNGGCSTPIAAYA 241
>HEM3_DEIRA (Q9RRY0) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 309 Score = 54.3 bits (129), Expect = 3e-07 Identities = 38/125 (30%), Positives = 57/125 (45%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GL R + D +LPA QGA+ + R+ DD +E +++ T + ER Sbjct: 174 GLIRTEQRHRIDEFVDPDILLPAPGQGALALETRTEDDLTIEVAYAIHDHATDDRITAER 233 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSGTYSFDDMVAIGQD 319 EFL+ L C P+ A+A K+G + G + + DG+ V + G VA D Sbjct: 234 EFLAGLGAGCMAPVGAHAV-IKNGLLTLEGWVGALDGTQVIRATSQGD------VAECAD 286 Query: 318 AGHEL 304 G EL Sbjct: 287 IGAEL 291
>HEM3_SCHPO (Q09899) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 336 Score = 54.3 bits (129), Expect = 3e-07 Identities = 33/101 (32%), Positives = 49/101 (48%), Gaps = 4/101 (3%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GL RL + + +L+ + AV QGA+ + R++D +M+E L L H++T A ER Sbjct: 182 GLFRLGLKDRIAQMLTAPFVYYAVGQGALAVEVRADDKEMIEMLKPLQHQETLYACLAER 241 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFR----GLLASPDG 388 + L G C PI N S+R G + S DG Sbjct: 242 ALMKRLQGGCAIPIGVQTDVLAISNSSYRISLLGTVLSADG 282
>HEM3_HELPY (P56140) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 306 Score = 53.9 bits (128), Expect = 4e-07 Identities = 34/99 (34%), Positives = 50/99 (50%), Gaps = 2/99 (2%) Frame = -2 Query: 633 SVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACEREFLSVLDGNCRTPIA 454 SV+EM+P++ QGA+G+ N K L LN E + EREF+ L+G C+ PI Sbjct: 186 SVEEMIPSMGQGALGVEMLKNH-KHFATLQKLNDEKSAFCCRLEREFIKGLNGGCQIPIG 244 Query: 453 AYAYRDKDGNCSFRGLLASPDGSIVYETSRSG--TYSFD 343 +A D + +L P+G V + G T +FD Sbjct: 245 VHASLMGD-RVKIQAVLGLPNGKEVITKEKQGDKTKAFD 282
>HEM3_METKA (Q8TXC8) Probable porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 305 Score = 52.8 bits (125), Expect = 1e-06 Identities = 27/85 (31%), Positives = 44/85 (51%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GL RL M + V +E +P QGA+ I CR +DD++ L ++ E +R+ V E+ Sbjct: 179 GLDRLGMTSEVSEVYDPEEFVPPAGQGALMITCRKDDDRVKRLLEVVDDEKSRVEVETEK 238 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGN 424 + L C P+ + R +DG+ Sbjct: 239 AVVRELGVGCSEPVGVHV-RARDGD 262
>HEM3_CAUCR (Q9ABZ8) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 322 Score = 51.2 bits (121), Expect = 3e-06 Identities = 42/134 (31%), Positives = 62/134 (46%), Gaps = 4/134 (2%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GL RL + S L D PA QGA+ I R+ +D +L ++ T +AVA ER Sbjct: 184 GLNRLGLGHLTRSWLDPDACPPAPGQGALVIETRA-EDIGAPWLEAVRCRQTTIAVAAER 242 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVY----ETSRSGTYSFDDMVA 331 L L+G+CRT I A A D S +PDG+ + + + +G + A Sbjct: 243 GALLALEGSCRTAIGARAILD-GARLSMIVEALTPDGAQRFRREGDITLTGADDIAEARA 301 Query: 330 IGQDAGHELKSKAG 289 G G E+++ G Sbjct: 302 FGLTLGAEVRAAGG 315
>HEM3_YEAST (P28789) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 327 Score = 50.8 bits (120), Expect = 4e-06 Identities = 29/103 (28%), Positives = 46/103 (44%), Gaps = 1/103 (0%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GL R+ + T D M AV QGA+GI R D KMM+ L + + + ER Sbjct: 182 GLMRMGLENRITQRFHSDTMYHAVGQGALGIEIRKGDTKMMKILDEICDLNATICCLSER 241 Query: 498 EFLSVLDGNCRTPIAAYA-YRDKDGNCSFRGLLASPDGSIVYE 373 + L+G C PI + Y ++ + ++ +G+ E Sbjct: 242 ALMRTLEGGCSVPIGVESKYNEETKKLLLKAIVVDVEGTEAVE 284
>HEM3_NEUCR (Q6MW51) Porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 337 Score = 50.8 bits (120), Expect = 4e-06 Identities = 33/117 (28%), Positives = 50/117 (42%), Gaps = 1/117 (0%) Frame = -2 Query: 621 MLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACEREFLSVLDGNCRTPIAAYAY 442 ML AV QGA+ + R D+K +E + L HE T +A ER + L+G C PI Sbjct: 204 MLHAVGQGALAMEIREGDEKTLEIIKPLCHEKTMVATFAERAVMRTLEGGCSVPIGVETK 263 Query: 441 RDKDGNCSFRGLLASPDG-SIVYETSRSGTYSFDDMVAIGQDAGHELKSKAGPGFFD 274 + + + S DG V S + ++ A+GQ +L + D Sbjct: 264 WVGEDQLQLKVTVVSLDGKESVDGQSVEVIKTIEEAEAMGQKLAEDLAKRGAQKILD 320
>HEM3_SULSO (Q980U4) Probable porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 293 Score = 49.7 bits (117), Expect = 8e-06 Identities = 40/129 (31%), Positives = 63/129 (48%), Gaps = 2/129 (1%) Frame = -2 Query: 675 LKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACERE 496 +KRL+++ + L+V + P QG I + R D+K+ E + H+DT ER Sbjct: 166 IKRLNIS-ISYHRLNVYDFTPEANQGIIVVLGRKKDEKVKEVFKEITHKDTLDEALAERA 224 Query: 495 FLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDG--SIVYETSRSGTYSFDDMVAIGQ 322 +SV+ G C +PI +R K+G F G+ + DG I S++G D IG Sbjct: 225 TISVVGGGCHSPIGV-LFR-KEGK-EFYGIASYSDGKKKITVSISKAG-----DPYTIGS 276 Query: 321 DAGHELKSK 295 + G LK + Sbjct: 277 ELGLLLKKE 285
>HEM3_METAC (Q8TT56) Probable porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 317 Score = 47.8 bits (112), Expect = 3e-05 Identities = 28/83 (33%), Positives = 44/83 (53%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GL+R+ E +LS D P+ QG + + R+ D ++ +S L+H ++R+ ER Sbjct: 167 GLERMGW-EIDGEILSPDFFCPSPNQGTVAVVTRA-DPEIEAAVSGLDHTESRIVTEIER 224 Query: 498 EFLSVLDGNCRTPIAAYAYRDKD 430 +S L G C TPI +YA D Sbjct: 225 ILISELGGGCTTPIGSYAELTSD 247
>HEM3_SULTO (Q976H1) Probable porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 294 Score = 44.7 bits (104), Expect = 3e-04 Identities = 25/77 (32%), Positives = 40/77 (51%), Gaps = 1/77 (1%) Frame = -2 Query: 615 PAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACEREFLSVLDGNCRTPIAAYAYR- 439 P QG I + R D+ + + + +N +DT ER+ LS++ G C +PI Y + Sbjct: 185 PEANQGIIVVIGRKKDETIKKIFNEINDKDTLEIAIAERKALSIVGGGCHSPIGVYFEKY 244 Query: 438 DKDGNCSFRGLLASPDG 388 DKD F G+++S G Sbjct: 245 DKD----FHGIISSSFG 257
>HEM3_HALSA (Q9HMY5) Probable porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 396 Score = 43.1 bits (100), Expect = 8e-04 Identities = 23/64 (35%), Positives = 31/64 (48%) Frame = -2 Query: 636 LSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACEREFLSVLDGNCRTPI 457 LS +PA QGA+ + R + D + +L H TR+ V ER L L G C PI Sbjct: 273 LSTGTHVPATGQGALCVTARRDSDVVDTLRDALEHVRTRVEVTAERVVLEELGGGCIAPI 332 Query: 456 AAYA 445 +A Sbjct: 333 GVHA 336
>HEM3_METTH (O26960) Probable porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 289 Score = 41.6 bits (96), Expect = 0.002 Identities = 29/126 (23%), Positives = 56/126 (44%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GLKRL + E V+ PA QGA+ + R+ D +++ + + H + V E+ Sbjct: 165 GLKRLGLEEHIKRRFPVEYFTPAAGQGALAVITRA-DSELISSIGRITHHPSLQEVTAEK 223 Query: 498 EFLSVLDGNCRTPIAAYAYRDKDGNCSFRGLLASPDGSIVYETSRSGTYSFDDMVAIGQD 319 L L C+ P+ R + +L + +G ++ + + G + + IG+ Sbjct: 224 TLLRELGAGCQCPLGVIG-RATGNQLTLYAVLLTREGEMLRKVTVRGPLA--EAEDIGKK 280 Query: 318 AGHELK 301 A E++ Sbjct: 281 AAKEME 286
>HEM3_METMA (Q8PW57) Probable porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 316 Score = 41.6 bits (96), Expect = 0.002 Identities = 23/78 (29%), Positives = 39/78 (50%) Frame = -2 Query: 678 GLKRLHMAETATSVLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACER 499 GL+R+ E + S D P+ QG + + R + +S L+H ++R+ ER Sbjct: 167 GLERMGW-EIEGEIFSPDFFCPSPNQGTVAVVTREGTEAEAA-VSMLDHTESRIVTEIER 224 Query: 498 EFLSVLDGNCRTPIAAYA 445 ++ L G C TP+ +YA Sbjct: 225 ILIAELGGGCTTPVGSYA 242
>HEM3_AERPE (Q9Y9J0) Probable porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 305 Score = 37.7 bits (86), Expect = 0.032 Identities = 34/106 (32%), Positives = 41/106 (38%), Gaps = 2/106 (1%) Frame = -2 Query: 615 PAVAQGAIGIACR--SNDDKMMEYLSSLNHEDTRLAVACEREFLSVLDGNCRTPIAAYAY 442 PA QG + + R SN +KM L L+ ER L CRTP+AAYA Sbjct: 191 PAPGQGFVAVVARVGSNVEKM---LRDLDKPPWWHVAWAERGVLEGARAGCRTPVAAYAE 247 Query: 441 RDKDGNCSFRGLLASPDGSIVYETSRSGTYSFDDMVAIGQDAGHEL 304 SPDGS Y G ++ IG G EL Sbjct: 248 PLGRSMVRVTAAALSPDGSRAYWARAEG--RIEEARRIGVSLGEEL 291
>SMS2_MOUSE (Q9D4B1) Phosphatidylcholine:ceramide cholinephosphotransferase 2| (EC 2.7.-.-) (Sphingomyelin synthase 2) Length = 365 Score = 32.7 bits (73), Expect = 1.0 Identities = 23/58 (39%), Positives = 27/58 (46%), Gaps = 3/58 (5%) Frame = +2 Query: 164 FKWYSSICGTKFYHNYKKMVKNKINTI-RAWW--IFYCKPSKKPGPAFDFSSWPASWP 328 F WY S+ K N K V ++ N + RAWW IFY G SWP SWP Sbjct: 288 FWWYHSMANEK---NLK--VSSQTNFLSRAWWFPIFYFFEKNVQGSIPCCFSWPLSWP 340
>SMS2_HUMAN (Q8NHU3) Phosphatidylcholine:ceramide cholinephosphotransferase 2| (EC 2.7.-.-) (Sphingomyelin synthase 2) Length = 365 Score = 32.7 bits (73), Expect = 1.0 Identities = 23/58 (39%), Positives = 27/58 (46%), Gaps = 3/58 (5%) Frame = +2 Query: 164 FKWYSSICGTKFYHNYKKMVKNKINTI-RAWW--IFYCKPSKKPGPAFDFSSWPASWP 328 F WY S+ K N K V ++ N + RAWW IFY G SWP SWP Sbjct: 288 FWWYHSMANEK---NLK--VSSQTNFLSRAWWFPIFYFFEKNVQGSIPCCFSWPLSWP 340
>US426_GAHVG (Q05104) Hypothetical 15.7 kDa protein| Length = 142 Score = 32.3 bits (72), Expect = 1.4 Identities = 14/33 (42%), Positives = 17/33 (51%) Frame = +2 Query: 266 CKPSKKPGPAFDFSSWPASWPIATMSSKEYVPL 364 C P + F FSSW P+ TMS+ VPL Sbjct: 46 CLPPFRSSHCFTFSSWALGVPVRTMSNSRVVPL 78
>SRY_MUSSI (Q62565) Sex-determining region Y protein (Testis-determining| factor) Length = 311 Score = 32.0 bits (71), Expect = 1.8 Identities = 13/31 (41%), Positives = 18/31 (58%) Frame = +3 Query: 438 HDKHMPQLEFDSYHQEQTRILFHMQQLIWYL 530 HD H Q +F +H +Q + FH QQL + L Sbjct: 257 HDHHQQQQQFHDHHHQQQQQQFHDQQLTYLL 287
>HEM3_THEAC (Q9HKM5) Probable porphobilinogen deaminase (EC 2.5.1.61) (PBG)| (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) Length = 295 Score = 32.0 bits (71), Expect = 1.8 Identities = 19/57 (33%), Positives = 26/57 (45%) Frame = -2 Query: 627 DEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACEREFLSVLDGNCRTPI 457 ++ +PA QG I + K E LSS+N DT + ER L C TP+ Sbjct: 183 EKFVPAPNQGIIAVVSEDGS-KASEVLSSINDADTYDDMMAERSITQGLKLGCSTPV 238
>DAPA_STRPN (Q97R25) Dihydrodipicolinate synthase (EC 4.2.1.52) (DHDPS)| Length = 311 Score = 31.6 bits (70), Expect = 2.3 Identities = 13/39 (33%), Positives = 23/39 (58%) Frame = -2 Query: 606 AQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACEREFL 490 A G I +A +N D+M E +++ D + A A +R+F+ Sbjct: 205 ADGVISVASHTNGDEMHEMFTAIAESDMKKAAAIQRKFI 243
>SRY_MUSSP (Q62563) Sex-determining region Y protein (Testis-determining| factor) Length = 355 Score = 31.2 bits (69), Expect = 3.0 Identities = 22/110 (20%), Positives = 41/110 (37%) Frame = +3 Query: 186 VVQNSIITTRRW*KTKSTLSERGGYSIASHRRNQVQPLISVRGRHLGLSRPCHQKNMFHF 365 V + +W + ++ R +S A+H ++ Q ++ + P Q+ FH Sbjct: 93 VASTKLYNLLQWDRNPHAITYRQDWSRAAHLYSKNQQSFYLQPVDIPTGHPQQQQQQFH- 151 Query: 366 LMSRIL*SHLVKPIAPGMNSSHPCHDKHMPQLEFDSYHQEQTRILFHMQQ 515 +H HD H + +F +HQ+Q + H QQ Sbjct: 152 -------NH--------HQQKQQFHDHHQQKQQFHDHHQQQQQFHDHQQQ 186 Score = 30.8 bits (68), Expect = 4.0 Identities = 13/31 (41%), Positives = 18/31 (58%) Frame = +3 Query: 438 HDKHMPQLEFDSYHQEQTRILFHMQQLIWYL 530 HD H Q +F + Q+Q + FH QQL + L Sbjct: 301 HDHHQQQQQFHDHQQQQQQQQFHDQQLTYLL 331 Score = 30.4 bits (67), Expect = 5.2 Identities = 14/48 (29%), Positives = 24/48 (50%), Gaps = 3/48 (6%) Frame = +3 Query: 438 HDKHMPQLEFDSYHQEQTRILFH---MQQLIWYLHDSKRIDTPSFYHH 572 HD H + +F +HQ+Q + FH QQ ++ H ++ +HH Sbjct: 236 HDHHQQKQQFHDHHQQQQQQQFHDHPQQQQQFHDHPQQKQQFHDHHHH 283
>DAPA_STRR6 (Q8DPZ9) Dihydrodipicolinate synthase (EC 4.2.1.52) (DHDPS)| Length = 311 Score = 30.8 bits (68), Expect = 4.0 Identities = 13/39 (33%), Positives = 22/39 (56%) Frame = -2 Query: 606 AQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACEREFL 490 A G I +A +N D+M E ++ D + A A +R+F+ Sbjct: 205 ADGVISVASHTNGDEMHEMFIAIAESDVKKAAAIQRKFI 243
>VATE_SPIOL (Q41396) Vacuolar ATP synthase subunit E (EC 3.6.3.14) (V-ATPase E| subunit) (Vacuolar proton pump E subunit) Length = 229 Score = 30.4 bits (67), Expect = 5.2 Identities = 21/88 (23%), Positives = 41/88 (46%) Frame = -2 Query: 630 VDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAVACEREFLSVLDGNCRTPIAA 451 V + L + + + + CR +D ++E++ LN A E ++ + P Sbjct: 118 VVQSLLRLREPGVLLRCREDDVHLVEHV--LNSAKEEYAEKAEVHTPEIIVDSIHLPAGP 175 Query: 450 YAYRDKDGNCSFRGLLASPDGSIVYETS 367 +++ +CS +LAS DG IV+E + Sbjct: 176 SHHKEHGLHCSGGVVLASRDGKIVFENT 203
>AROH_SHIFL (P59736) Phospho-2-dehydro-3-deoxyheptonate aldolase, Trp-sensitive| (EC 2.5.1.54) (Phospho-2-keto-3-deoxyheptonate aldolase) (DAHP synthetase) (3-deoxy-D-arabino-heptulosonate 7-phosphate synthase) Length = 348 Score = 30.0 bits (66), Expect = 6.7 Identities = 22/85 (25%), Positives = 34/85 (40%), Gaps = 9/85 (10%) Frame = -2 Query: 534 HEDTRLAVACEREFLSVLDGNCRTPIAA---------YAYRDKDGNCSFRGLLASPDGSI 382 H + A++C F + DGN R + A + DK+G + +P G I Sbjct: 171 HREMASALSCPVGFKNGTDGNTRIAVDAIRAARASHMFLSPDKNGQMTIYQTSGNPYGHI 230 Query: 381 VYETSRSGTYSFDDMVAIGQDAGHE 307 + + Y DD +A D HE Sbjct: 231 IMRGGKKPNYHADD-IAAACDTLHE 254
>AROH_ECOLI (P00887) Phospho-2-dehydro-3-deoxyheptonate aldolase, Trp-sensitive| (EC 2.5.1.54) (Phospho-2-keto-3-deoxyheptonate aldolase) (DAHP synthetase) (3-deoxy-D-arabino-heptulosonate 7-phosphate synthase) Length = 348 Score = 30.0 bits (66), Expect = 6.7 Identities = 22/85 (25%), Positives = 34/85 (40%), Gaps = 9/85 (10%) Frame = -2 Query: 534 HEDTRLAVACEREFLSVLDGNCRTPIAA---------YAYRDKDGNCSFRGLLASPDGSI 382 H + A++C F + DGN R + A + DK+G + +P G I Sbjct: 171 HREMASALSCPVGFKNGTDGNTRIAVDAIRAARASHMFLSPDKNGQMTIYQTSGNPYGHI 230 Query: 381 VYETSRSGTYSFDDMVAIGQDAGHE 307 + + Y DD +A D HE Sbjct: 231 IMRGGKKPNYHADD-IAAACDTLHE 254
>AROH_ECOL6 (Q8FH32) Phospho-2-dehydro-3-deoxyheptonate aldolase, Trp-sensitive| (EC 2.5.1.54) (Phospho-2-keto-3-deoxyheptonate aldolase) (DAHP synthetase) (3-deoxy-D-arabino-heptulosonate 7-phosphate synthase) Length = 348 Score = 30.0 bits (66), Expect = 6.7 Identities = 22/85 (25%), Positives = 34/85 (40%), Gaps = 9/85 (10%) Frame = -2 Query: 534 HEDTRLAVACEREFLSVLDGNCRTPIAA---------YAYRDKDGNCSFRGLLASPDGSI 382 H + A++C F + DGN R + A + DK+G + +P G I Sbjct: 171 HREMASALSCPVGFKNGTDGNTRIAVDAIRAARASHMFLSPDKNGQMTIYQTSGNPYGHI 230 Query: 381 VYETSRSGTYSFDDMVAIGQDAGHE 307 + + Y DD +A D HE Sbjct: 231 IMRGGKKPNYHADD-IAAACDTLHE 254
>AROH_ECO57 (Q8X5W4) Phospho-2-dehydro-3-deoxyheptonate aldolase, Trp-sensitive| (EC 2.5.1.54) (Phospho-2-keto-3-deoxyheptonate aldolase) (DAHP synthetase) (3-deoxy-D-arabino-heptulosonate 7-phosphate synthase) Length = 348 Score = 30.0 bits (66), Expect = 6.7 Identities = 22/85 (25%), Positives = 34/85 (40%), Gaps = 9/85 (10%) Frame = -2 Query: 534 HEDTRLAVACEREFLSVLDGNCRTPIAA---------YAYRDKDGNCSFRGLLASPDGSI 382 H + A++C F + DGN R + A + DK+G + +P G I Sbjct: 171 HREMASALSCPVGFKNGTDGNTRIAVDAIRAARASHMFLSPDKNGQMTIYQTSGNPYGHI 230 Query: 381 VYETSRSGTYSFDDMVAIGQDAGHE 307 + + Y DD +A D HE Sbjct: 231 IMRGGKKPNYHADD-IAAACDTLHE 254
>ACKA2_NEIMB (Q9K0X1) Acetate kinase 2 (EC 2.7.2.1) (Acetokinase 2)| Length = 399 Score = 30.0 bits (66), Expect = 6.7 Identities = 18/43 (41%), Positives = 25/43 (58%) Frame = -2 Query: 639 VLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAV 511 V VDEML + G +GI+ SND + +E + HE RLA+ Sbjct: 259 VAQVDEMLNKKS-GLLGISELSNDCRTLEIAADEGHEGARLAL 300
>ACKA2_NEIMA (Q9JT07) Acetate kinase 2 (EC 2.7.2.1) (Acetokinase 2)| Length = 399 Score = 30.0 bits (66), Expect = 6.7 Identities = 18/43 (41%), Positives = 25/43 (58%) Frame = -2 Query: 639 VLSVDEMLPAVAQGAIGIACRSNDDKMMEYLSSLNHEDTRLAV 511 V VDEML + G +GI+ SND + +E + HE RLA+ Sbjct: 259 VAQVDEMLNKKS-GLLGISELSNDCRTLEIAADEGHEGARLAL 300
>AROH_BUCAI (P57224) Phospho-2-dehydro-3-deoxyheptonate aldolase, Trp-sensitive| (EC 2.5.1.54) (Phospho-2-keto-3-deoxyheptonate aldolase) (DAHP synthetase) (3-deoxy-D-arabino-heptulosonate 7-phosphate synthase) Length = 348 Score = 29.6 bits (65), Expect = 8.8 Identities = 20/75 (26%), Positives = 31/75 (41%), Gaps = 9/75 (12%) Frame = -2 Query: 534 HEDTRLAVACEREFLSVLDGNCRTPIAA---------YAYRDKDGNCSFRGLLASPDGSI 382 H + A++C F + DGN R I A + +KDG + +P G I Sbjct: 171 HREMASALSCPVGFKNGTDGNIRIAIDAIRAAKVRHLFFAPNKDGQMTINHTSGNPYGHI 230 Query: 381 VYETSRSGTYSFDDM 337 + R+ Y DD+ Sbjct: 231 IMRGGRAPNYHPDDI 245 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 97,154,902 Number of Sequences: 219361 Number of extensions: 2042773 Number of successful extensions: 5508 Number of sequences better than 10.0: 156 Number of HSP's better than 10.0 without gapping: 5300 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5463 length of database: 80,573,946 effective HSP length: 108 effective length of database: 56,882,958 effective search space used: 6655306086 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
