Clone Information

BLAST Search Result

Clone Name	rbags17l09
Clone Library Name	barley_pub

No.	Definition	Score (bits)	E Value
1	UPL2_ARATH (Q8H0T4) E3 ubiquitin protein ligase UPL2 (EC 6.3.2.-...	187	3e-47
2	UPL1_ARATH (Q8GY23) E3 ubiquitin protein ligase UPL1 (EC 6.3.2.-...	183	5e-46
3	PTR1_SCHPO (O13834) E3 ubiquitin protein ligase ptr1 (EC 6.3.2.-...	148	1e-35
4	HUWE1_RAT (P51593) HECT, UBA and WWE domain-containing protein 1...	134	2e-31
5	HUWE1_HUMAN (Q7Z6Z7) HECT, UBA and WWE domain-containing protein...	134	2e-31
6	HUWE1_MOUSE (Q7TMY8) HECT, UBA and WWE domain-containing protein...	134	2e-31
7	TOM1_NEUCR (Q9P4Z1) E3 ubiquitin protein ligase TOM1-like protei...	131	2e-30
8	TOM1_ASHGO (Q756G2) Probable E3 ubiquitin protein ligase TOM1 (E...	125	1e-28
9	PUB3_SCHPO (O14326) E3 ubiquitin--protein ligase pub3 (EC 6.3.2.-)	121	2e-27
10	TOM1_YEAST (Q03280) E3 ubiquitin protein ligase TOM1 (EC 6.3.2.-...	119	6e-27
11	SMUF2_HUMAN (Q9HAU4) Smad ubiquitination regulatory factor 2 (EC...	116	7e-26
12	PUB1_SCHPO (Q92462) E3 ubiquitin--protein ligase pub1 (EC 6.3.2.-)	114	2e-25
13	RSP5_YEAST (P39940) E3 ubiquitin--protein ligase RSP5 (EC 6.3.2.-)	112	1e-24
14	SMUF1_XENLA (Q9PUN2) Smad ubiquitination regulatory factor 1 (EC...	110	4e-24
15	ITCH_MOUSE (Q8C863) Itchy E3 ubiquitin protein ligase (EC 6.3.2.-)	108	1e-23
16	ITCH_HUMAN (Q96J02) Itchy homolog E3 ubiquitin protein ligase (E...	108	1e-23
17	NED4L_MOUSE (Q8CFI0) E3 ubiquitin-protein ligase NEDD4-like prot...	108	2e-23
18	NED4L_PONPY (Q5RBF2) E3 ubiquitin-protein ligase NEDD4-like prot...	108	2e-23
19	PUB2_SCHPO (Q9UTG2) E3 ubiquitin--protein ligase pub2 (EC 6.3.2.-)	108	2e-23
20	NED4L_HUMAN (Q96PU5) E3 ubiquitin-protein ligase NEDD4-like prot...	108	2e-23
21	SMUF1_HUMAN (Q9HCE7) Smad ubiquitination regulatory factor 1 (EC...	107	2e-23
22	NEDD4_DROME (Q9VVI3) E3 ubiquitin-protein ligase Nedd-4 (EC 6.3....	107	2e-23
23	SMUF1_MOUSE (Q9CUN6) Smad ubiquitination regulatory factor 1 (EC...	107	2e-23
24	WWP2_MOUSE (Q9DBH0) NEDD4-like E3 ubiquitin-protein ligase WWP2 ...	107	4e-23
25	WWP2_HUMAN (O00308) NEDD4-like E3 ubiquitin-protein ligase WWP2 ...	107	4e-23
26	NEDD4_RAT (Q62940) E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-)	105	9e-23
27	NEDD4_MOUSE (P46935) E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2...	105	1e-22
28	NEDD4_HUMAN (P46934) E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-)	104	2e-22
29	SUDX_DROME (Q9Y0H4) E3 ubiquitin-protein ligase suppressor of de...	104	3e-22
30	WWP1_MOUSE (Q8BZZ3) NEDD4-like E3 ubiquitin-protein ligase WWP1 ...	104	3e-22
31	WWP1_HUMAN (Q9H0M0) NEDD4-like E3 ubiquitin-protein ligase WWP1 ...	104	3e-22
32	SMUF1_DROME (Q9V853) E3 ubiquitin-protein ligase Smurf1 (EC 6.3....	96	1e-19
33	UBE3A_HUMAN (Q05086) Ubiquitin-protein ligase E3A (EC 6.3.2.-) (...	88	2e-17
34	UBE3A_MOUSE (O08759) Ubiquitin-protein ligase E3A (EC 6.3.2.-) (...	84	4e-16
35	K0317_MOUSE (Q8CHG5) Protein KIAA0317	84	4e-16
36	K0317_HUMAN (O15033) Protein KIAA0317	84	4e-16
37	HUL4_ASHGO (Q757T0) Probable ubiquitin-protein ligase HUL4 (EC 6...	82	2e-15
38	UBE3C_HUMAN (Q15386) Ubiquitin-protein ligase E3C (EC 6.3.2.-)	78	3e-14
39	UBE3C_MOUSE (Q80U95) Ubiquitin-protein ligase E3C (EC 6.3.2.-)	77	4e-14
40	HERC3_HUMAN (Q15034) HECT domain and RCC1-like domain protein 3	77	6e-14
41	HUL4_YEAST (P40985) Probable ubiquitin-protein ligase HUL4 (EC 6...	74	3e-13
42	UFD4_YEAST (P33202) Ubiquitin fusion degradation protein 4 (UB f...	73	9e-13
43	HUL5_YEAST (P53119) Probable ubiquitin-protein ligase HUL5 (EC 6...	72	1e-12
44	TRIPC_HUMAN (Q14669) Thyroid receptor-interacting protein 12 (TR...	72	1e-12
45	YDE1_SCHPO (Q10435) Probable ubiquitin fusion degradation protei...	68	3e-11
46	HERC2_HUMAN (O95714) HECT domain and RCC1-like domain-containing...	67	6e-11
47	HERC2_MOUSE (Q4U2R1) HECT domain and RCC1-like domain-containing...	66	8e-11
48	HECD1_HUMAN (Q9ULT8) E3 ubiquitin-protein ligase HECTD1 (HECT do...	61	3e-09
49	HERC2_DROME (Q9VR91) HECT domain and RCC1-like domain-containing...	60	5e-09
50	HYD_DROME (P51592) Ubiquitin--protein ligase hyd (EC 6.3.2.-) (P...	58	2e-08
51	EDD1_MOUSE (Q80TP3) Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (...	58	3e-08
52	EDD1_HUMAN (O95071) Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (...	58	3e-08
53	EDD1_RAT (Q62671) Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hy...	58	3e-08
54	HERC5_HUMAN (Q9UII4) HECT domain and RCC1-like domain-containing...	52	2e-06
55	GLMM_PHOLL (Q7MYY3) Phosphoglucosamine mutase (EC 5.4.2.10)	30	5.0
56	CENB2_HUMAN (Q15057) Centaurin-beta 2 (Cnt-b2)	30	5.0
57	MUT7_CAEEL (P34607) Probable exonuclease mut-7 (EC 3.1.-.-)	30	5.0
58	FBN3_HUMAN (Q75N90) Fibrillin-3 precursor	30	5.0

>UPL2_ARATH (Q8H0T4) E3 ubiquitin protein ligase UPL2 (EC 6.3.2.-)|
            (Ubiquitin-protein ligase 2)
          Length = 3658

 Score =  187 bits (474), Expect = 3e-47
 Identities = 87/103 (84%), Positives = 94/103 (91%)
 Frame = -3

Query: 663  YSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAYG 484
            Y++ SPVI+WFWE+V+ FSKED ARFLQFVTGTSKVPLEGF ALQGISGPQR QIHKAYG
Sbjct: 3555 YTVGSPVIRWFWEVVKAFSKEDMARFLQFVTGTSKVPLEGFKALQGISGPQRLQIHKAYG 3614

Query: 483  STNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGFGF 355
            S   LPSAHTCFNQLDLPEY SK+Q+QERLLLAIHEANEGFGF
Sbjct: 3615 SPERLPSAHTCFNQLDLPEYQSKEQVQERLLLAIHEANEGFGF 3657

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>UPL1_ARATH (Q8GY23) E3 ubiquitin protein ligase UPL1 (EC 6.3.2.-)|
            (Ubiquitin-protein ligase 1)
          Length = 3684

 Score =  183 bits (464), Expect = 5e-46
 Identities = 86/103 (83%), Positives = 92/103 (89%)
 Frame = -3

Query: 663  YSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAYG 484
            Y+  SPVI WFWE+V+ FSKED ARFLQFVTGTSKVPLEGF ALQGISGPQR QIHKAYG
Sbjct: 3578 YTAGSPVIHWFWEVVKAFSKEDMARFLQFVTGTSKVPLEGFKALQGISGPQRLQIHKAYG 3637

Query: 483  STNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGFGF 355
            +   LPSAHTCFNQLDLPEY SK+QLQERLLLAIHEA+EGFGF
Sbjct: 3638 APERLPSAHTCFNQLDLPEYQSKEQLQERLLLAIHEASEGFGF 3680

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>PTR1_SCHPO (O13834) E3 ubiquitin protein ligase ptr1 (EC 6.3.2.-) (Poly(A)+ RNA|
            transport protein 1)
          Length = 3227

 Score =  148 bits (374), Expect = 1e-35
 Identities = 65/104 (62%), Positives = 83/104 (79%)
 Frame = -3

Query: 666  GYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAY 487
            GY+++SP +QWFW  V+ F +E++A+ LQF TGTSKVPL GF  L+G+SG QRF IHK+Y
Sbjct: 3123 GYNVSSPQVQWFWRAVRSFDEEERAKLLQFATGTSKVPLNGFKELEGMSGFQRFNIHKSY 3182

Query: 486  GSTNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGFGF 355
            GS N LP +HTCFNQLDLPEY + +QL+  LL AI+E +EGFGF
Sbjct: 3183 GSLNRLPQSHTCFNQLDLPEYDTYEQLRSMLLTAINEGSEGFGF 3226

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>HUWE1_RAT (P51593) HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-)|
           (E3 ubiquitin protein ligase URE-B1) (Upstream
           regulatory element-binding protein 1) (Fragment)
          Length = 322

 Score =  134 bits (337), Expect = 2e-31
 Identities = 63/102 (61%), Positives = 80/102 (78%)
 Frame = -3

Query: 663 YSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAYG 484
           Y   S  IQWFW  ++ F + D+A+FLQFVTGTSKVPL+GF+AL+G++G Q+FQIH+   
Sbjct: 219 YQSNSIQIQWFWRALRSFDQADRAKFLQFVTGTSKVPLQGFAALEGMNGIQKFQIHRDDR 278

Query: 483 STNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGFG 358
           ST+ LPSAHTCFNQLDLP Y S ++L+  LLLAI E +EGFG
Sbjct: 279 STDRLPSAHTCFNQLDLPAYESFEKLRHMLLLAIQECSEGFG 320

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>HUWE1_HUMAN (Q7Z6Z7) HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-)|
            (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin
            ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1)
          Length = 4374

 Score =  134 bits (337), Expect = 2e-31
 Identities = 63/102 (61%), Positives = 80/102 (78%)
 Frame = -3

Query: 663  YSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAYG 484
            Y   S  IQWFW  ++ F + D+A+FLQFVTGTSKVPL+GF+AL+G++G Q+FQIH+   
Sbjct: 4271 YQSNSIQIQWFWRALRSFDQADRAKFLQFVTGTSKVPLQGFAALEGMNGIQKFQIHRDDR 4330

Query: 483  STNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGFG 358
            ST+ LPSAHTCFNQLDLP Y S ++L+  LLLAI E +EGFG
Sbjct: 4331 STDRLPSAHTCFNQLDLPAYESFEKLRHMLLLAIQECSEGFG 4372

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>HUWE1_MOUSE (Q7TMY8) HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-)|
            (E3 ubiquitin protein ligase URE-B1) (E3Histone)
          Length = 4377

 Score =  134 bits (337), Expect = 2e-31
 Identities = 63/102 (61%), Positives = 80/102 (78%)
 Frame = -3

Query: 663  YSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAYG 484
            Y   S  IQWFW  ++ F + D+A+FLQFVTGTSKVPL+GF+AL+G++G Q+FQIH+   
Sbjct: 4274 YQSNSIQIQWFWRALRSFDQADRAKFLQFVTGTSKVPLQGFAALEGMNGIQKFQIHRDDR 4333

Query: 483  STNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGFG 358
            ST+ LPSAHTCFNQLDLP Y S ++L+  LLLAI E +EGFG
Sbjct: 4334 STDRLPSAHTCFNQLDLPAYESFEKLRHMLLLAIQECSEGFG 4375

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>TOM1_NEUCR (Q9P4Z1) E3 ubiquitin protein ligase TOM1-like protein (EC 6.3.2.-)|
          Length = 4065

 Score =  131 bits (329), Expect = 2e-30
 Identities = 60/103 (58%), Positives = 76/103 (73%)
 Frame = -3

Query: 663  YSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAYG 484
            YS  +P IQWFW  V+ F KE+ A+ LQFVTGTSKVPL GF  L+G++G  RF IH+ YG
Sbjct: 3962 YSAGAPQIQWFWRAVRSFDKEELAKLLQFVTGTSKVPLNGFKELEGMNGVSRFNIHRDYG 4021

Query: 483  STNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGFGF 355
            S + LPS+HTCFNQLDLPEY + + L+ +LL AI   ++ FGF
Sbjct: 4022 SKDRLPSSHTCFNQLDLPEYENYETLRSQLLKAITAGSDYFGF 4064

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>TOM1_ASHGO (Q756G2) Probable E3 ubiquitin protein ligase TOM1 (EC 6.3.2.-)|
          Length = 3258

 Score =  125 bits (314), Expect = 1e-28
 Identities = 58/102 (56%), Positives = 74/102 (72%)
 Frame = -3

Query: 663  YSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAYG 484
            Y+     I +FW  V+ F KE++A+ LQFVTGTSKVPL GF  L G++G  +F IH+ YG
Sbjct: 3155 YTPTCKQINYFWRAVRSFDKEERAKLLQFVTGTSKVPLNGFKELSGVNGISKFSIHRDYG 3214

Query: 483  STNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGFG 358
            S + LPS+HTCFNQLDLP Y S + L+  LLLAI+E +EGFG
Sbjct: 3215 SIDRLPSSHTCFNQLDLPAYDSYETLRGSLLLAINEGHEGFG 3256

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>PUB3_SCHPO (O14326) E3 ubiquitin--protein ligase pub3 (EC 6.3.2.-)|
          Length = 786

 Score =  121 bits (303), Expect = 2e-27
 Identities = 57/102 (55%), Positives = 74/102 (72%)
 Frame = -3

Query: 663 YSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAYG 484
           Y    PVI+WFWEI+ G+  ED+++ LQF TGTS++P+ GF  LQG  GP++F I KA G
Sbjct: 685 YIATDPVIKWFWEIIAGWKNEDRSKLLQFATGTSRIPVNGFRDLQGSDGPRKFTIEKA-G 743

Query: 483 STNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGFG 358
           + + LP AHTCFN+LDLP+Y SKD L E+L LA+ E   GFG
Sbjct: 744 TPDQLPVAHTCFNRLDLPDYPSKDTLHEKLSLAV-ENTVGFG 784

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>TOM1_YEAST (Q03280) E3 ubiquitin protein ligase TOM1 (EC 6.3.2.-)|
            (Temperature-dependent organization in mitotic nucleus
            protein 1) (Suppressor of snRNA protein 2)
          Length = 3268

 Score =  119 bits (299), Expect = 6e-27
 Identities = 54/102 (52%), Positives = 73/102 (71%)
 Frame = -3

Query: 663  YSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAYG 484
            Y+     + +FW  V+ F  E++A+ LQFVTGTSKVPL GF  L G++G  +F IH+ +G
Sbjct: 3165 YTATCKEVSYFWRAVRSFDAEERAKLLQFVTGTSKVPLNGFKELSGVNGVCKFSIHRDFG 3224

Query: 483  STNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGFG 358
            S+  LPS+HTCFNQL+LP Y S + L+  LLLAI+E +EGFG
Sbjct: 3225 SSERLPSSHTCFNQLNLPPYESYETLRGSLLLAINEGHEGFG 3266

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>SMUF2_HUMAN (Q9HAU4) Smad ubiquitination regulatory factor 2 (EC 6.3.2.-)|
           (Ubiquitin--protein ligase SMURF2) (Smad-specific E3
           ubiquitin ligase 2) (hSMURF2)
          Length = 748

 Score =  116 bits (290), Expect = 7e-26
 Identities = 51/92 (55%), Positives = 71/92 (77%)
 Frame = -3

Query: 651 SPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAYGSTNH 472
           S +++WFW+ V+ F +E +AR LQFVTG+S+VPL+GF ALQG +GP+ F IH+    TN+
Sbjct: 650 SNIVKWFWKAVEFFDEERRARLLQFVTGSSRVPLQGFKALQGAAGPRLFTIHQIDACTNN 709

Query: 471 LPSAHTCFNQLDLPEYTSKDQLQERLLLAIHE 376
           LP AHTCFN++D+P Y S ++L E+LL AI E
Sbjct: 710 LPKAHTCFNRIDIPPYESYEKLYEKLLTAIEE 741

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>PUB1_SCHPO (Q92462) E3 ubiquitin--protein ligase pub1 (EC 6.3.2.-)|
          Length = 767

 Score =  114 bits (286), Expect = 2e-25
 Identities = 55/104 (52%), Positives = 70/104 (67%)
 Frame = -3

Query: 663 YSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAYG 484
           YS    +I+WFWE++  +S E K+R LQF TGTS++P+ GF  LQG  GP++F I KA G
Sbjct: 666 YSENDQIIKWFWELMDEWSNEKKSRLLQFTTGTSRIPVNGFKDLQGSDGPRKFTIEKA-G 724

Query: 483 STNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGFGFG 352
             N LP AHTCFN+LDLP YTSK  L  +L +A+ E     GFG
Sbjct: 725 EPNKLPKAHTCFNRLDLPPYTSKKDLDHKLSIAVEET---IGFG 765

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>RSP5_YEAST (P39940) E3 ubiquitin--protein ligase RSP5 (EC 6.3.2.-)|
          Length = 809

 Score =  112 bits (280), Expect = 1e-24
 Identities = 52/105 (49%), Positives = 69/105 (65%)
 Frame = -3

Query: 666  GYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAY 487
            GY  +  VIQWFW+ V  +  E +AR LQF TGTS++P+ GF  LQG  GP+RF I KA 
Sbjct: 707  GYQESDEVIQWFWKCVSEWDNEQRARLLQFTTGTSRIPVNGFKDLQGSDGPRRFTIEKA- 765

Query: 486  GSTNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGFGFG 352
            G    LP +HTCFN++DLP+Y   D ++++L LA+ E     GFG
Sbjct: 766  GEVQQLPKSHTCFNRVDLPQYVDYDSMKQKLTLAVEET---IGFG 807

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>SMUF1_XENLA (Q9PUN2) Smad ubiquitination regulatory factor 1 (EC 6.3.2.-)|
           (Ubiquitin--protein ligase SMURF1) (Smad-specific E3
           ubiquitin ligase) (xSMURF1)
          Length = 731

 Score =  110 bits (275), Expect = 4e-24
 Identities = 49/97 (50%), Positives = 72/97 (74%), Gaps = 3/97 (3%)
 Frame = -3

Query: 651 SPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQ---GISGPQRFQIHKAYGS 481
           S ++QWFW+ V+ F +E +AR LQFVTG+++VPL+GF ALQ   G +GP+ F IH    +
Sbjct: 630 SNIVQWFWQAVESFDEERRARLLQFVTGSTRVPLQGFKALQGSTGAAGPRLFTIHLIDAN 689

Query: 480 TNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEAN 370
           T++LP AHTCFN++D+P Y S ++L E+LL A+ E +
Sbjct: 690 TDNLPKAHTCFNRIDIPPYESYEKLYEKLLTAVEETS 726

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>ITCH_MOUSE (Q8C863) Itchy E3 ubiquitin protein ligase (EC 6.3.2.-)|
          Length = 864

 Score =  108 bits (270), Expect = 1e-23
 Identities = 54/102 (52%), Positives = 69/102 (67%)
 Frame = -3

Query: 663  YSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAYG 484
            Y+  S  I WFW+ V+    E + R LQFVTGT ++P+ GF+ L G +GPQ+F I K  G
Sbjct: 763  YTRTSKQIMWFWQFVKEIDNEKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKV-G 821

Query: 483  STNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGFG 358
              N LP +HTCFN+LDLP Y S +QL+E+LL AI E  EGFG
Sbjct: 822  KENWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEE-TEGFG 862

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>ITCH_HUMAN (Q96J02) Itchy homolog E3 ubiquitin protein ligase (EC 6.3.2.-)|
            (Itch) (Atrophin-1-interacting protein 4) (AIP4)
            (NFE2-associated polypeptide 1) (NAPP1)
          Length = 903

 Score =  108 bits (270), Expect = 1e-23
 Identities = 54/102 (52%), Positives = 69/102 (67%)
 Frame = -3

Query: 663  YSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAYG 484
            Y+  S  I WFW+ V+    E + R LQFVTGT ++P+ GF+ L G +GPQ+F I K  G
Sbjct: 802  YARTSKQIMWFWQFVKEIDNEKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKV-G 860

Query: 483  STNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGFG 358
              N LP +HTCFN+LDLP Y S +QL+E+LL AI E  EGFG
Sbjct: 861  KENWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEE-TEGFG 901

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>NED4L_MOUSE (Q8CFI0) E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-)|
            (Nedd4-2) (NEDD4.2)
          Length = 1004

 Score =  108 bits (269), Expect = 2e-23
 Identities = 54/102 (52%), Positives = 70/102 (68%)
 Frame = -3

Query: 666  GYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAY 487
            GY    PVIQWFW+ V     E + R LQFVTGTS+VP+ GF+ L G +GPQ F I + +
Sbjct: 901  GYCPNHPVIQWFWKAVLLMDAEKRIRLLQFVTGTSRVPMNGFAELYGSNGPQLFTIEQ-W 959

Query: 486  GSTNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGF 361
            GS   LP AHTCFN+LDLP Y + + L+E+LL+A+  A +GF
Sbjct: 960  GSPEKLPRAHTCFNRLDLPPYETFEDLREKLLMAVENA-QGF 1000

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>NED4L_PONPY (Q5RBF2) E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-)|
          Length = 959

 Score =  108 bits (269), Expect = 2e-23
 Identities = 54/102 (52%), Positives = 70/102 (68%)
 Frame = -3

Query: 666  GYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAY 487
            GY    PVIQWFW+ V     E + R LQFVTGTS+VP+ GF+ L G +GPQ F I + +
Sbjct: 856  GYCPNHPVIQWFWKAVLLMDAEKRIRLLQFVTGTSRVPMNGFAELYGSNGPQLFTIEQ-W 914

Query: 486  GSTNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGF 361
            GS   LP AHTCFN+LDLP Y + + L+E+LL+A+  A +GF
Sbjct: 915  GSPEKLPRAHTCFNRLDLPPYETFEDLREKLLMAVENA-QGF 955

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>PUB2_SCHPO (Q9UTG2) E3 ubiquitin--protein ligase pub2 (EC 6.3.2.-)|
          Length = 671

 Score =  108 bits (269), Expect = 2e-23
 Identities = 49/102 (48%), Positives = 70/102 (68%)
 Frame = -3

Query: 663 YSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAYG 484
           Y+    ++ WFWE++  +S E KA+ LQF TGTS++PL GF  + G  GP++F I K  G
Sbjct: 570 YTETDDIVIWFWELLSEWSPEKKAKLLQFATGTSRLPLSGFKDMHGSDGPRKFTIEKV-G 628

Query: 483 STNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGFG 358
             + LP AHTCFN+LD+P Y SK++L+++L +AI E   GFG
Sbjct: 629 HISQLPKAHTCFNRLDIPPYNSKEELEQKLTIAIQE-TAGFG 669

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>NED4L_HUMAN (Q96PU5) E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-)|
            (Nedd4-2) (NEDD4.2)
          Length = 975

 Score =  108 bits (269), Expect = 2e-23
 Identities = 54/102 (52%), Positives = 70/102 (68%)
 Frame = -3

Query: 666  GYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAY 487
            GY    PVIQWFW+ V     E + R LQFVTGTS+VP+ GF+ L G +GPQ F I + +
Sbjct: 872  GYCPNHPVIQWFWKAVLLMDAEKRIRLLQFVTGTSRVPMNGFAELYGSNGPQLFTIEQ-W 930

Query: 486  GSTNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGF 361
            GS   LP AHTCFN+LDLP Y + + L+E+LL+A+  A +GF
Sbjct: 931  GSPEKLPRAHTCFNRLDLPPYETFEDLREKLLMAVENA-QGF 971

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>SMUF1_HUMAN (Q9HCE7) Smad ubiquitination regulatory factor 1 (EC 6.3.2.-)|
           (Ubiquitin--protein ligase SMURF1) (Smad-specific E3
           ubiquitin ligase 1) (hSMURF1)
          Length = 757

 Score =  107 bits (268), Expect = 2e-23
 Identities = 48/95 (50%), Positives = 71/95 (74%), Gaps = 3/95 (3%)
 Frame = -3

Query: 651 SPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQ---GISGPQRFQIHKAYGS 481
           S +++WFW+ V+ F +E +AR LQFVTG+++VPL+GF ALQ   G +GP+ F IH    +
Sbjct: 656 SNIVRWFWQAVETFDEERRARLLQFVTGSTRVPLQGFKALQGSTGAAGPRLFTIHLIDAN 715

Query: 480 TNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHE 376
           T++LP AHTCFN++D+P Y S ++L E+LL A+ E
Sbjct: 716 TDNLPKAHTCFNRIDIPPYESYEKLYEKLLTAVEE 750

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>NEDD4_DROME (Q9VVI3) E3 ubiquitin-protein ligase Nedd-4 (EC 6.3.2.-) (DNedd4)|
          Length = 1007

 Score =  107 bits (268), Expect = 2e-23
 Identities = 53/101 (52%), Positives = 70/101 (69%)
 Frame = -3

Query: 663  YSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAYG 484
            Y +   +IQWFW  V  FS E ++R LQFVTGTS+VP+ GF  L G +GPQ F I K +G
Sbjct: 905  YHMNHIIIQWFWRAVLSFSNEMRSRLLQFVTGTSRVPMNGFKELYGSNGPQMFTIEK-WG 963

Query: 483  STNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGF 361
            + N+ P AHTCFN+LDLP Y    QL+++L+ AI E ++GF
Sbjct: 964  TPNNFPRAHTCFNRLDLPPYEGYLQLKDKLIKAI-EGSQGF 1003

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>SMUF1_MOUSE (Q9CUN6) Smad ubiquitination regulatory factor 1 (EC 6.3.2.-)|
           (Ubiquitin--protein ligase SMURF1) (Smad-specific E3
           ubiquitin ligase 1)
          Length = 731

 Score =  107 bits (268), Expect = 2e-23
 Identities = 48/95 (50%), Positives = 71/95 (74%), Gaps = 3/95 (3%)
 Frame = -3

Query: 651 SPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQ---GISGPQRFQIHKAYGS 481
           S +++WFW+ V+ F +E +AR LQFVTG+++VPL+GF ALQ   G +GP+ F IH    +
Sbjct: 630 SNIVRWFWQAVETFDEERRARLLQFVTGSTRVPLQGFKALQGSTGAAGPRLFTIHLIDAN 689

Query: 480 TNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHE 376
           T++LP AHTCFN++D+P Y S ++L E+LL A+ E
Sbjct: 690 TDNLPKAHTCFNRIDIPPYESYEKLYEKLLTAVEE 724

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>WWP2_MOUSE (Q9DBH0) NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW|
            domain-containing protein 2)
          Length = 870

 Score =  107 bits (266), Expect = 4e-23
 Identities = 53/102 (51%), Positives = 71/102 (69%)
 Frame = -3

Query: 663  YSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAYG 484
            Y+ +S  IQWFW++V+    E + R LQFVTGT ++P+ GF+ L G +GPQ+F I +  G
Sbjct: 769  YTKSSKQIQWFWQVVKEMDNEKRIRLLQFVTGTCRLPVGGFAELIGSNGPQKFCIDRV-G 827

Query: 483  STNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGFG 358
                LP +HTCFN+LDLP Y S +QL+E+LL AI E  EGFG
Sbjct: 828  KETWLPRSHTCFNRLDLPPYKSYEQLKEKLLYAIEE-TEGFG 868

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>WWP2_HUMAN (O00308) NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW|
            domain-containing protein 2) (Atrophin-1-interacting
            protein 2) (AIP2)
          Length = 870

 Score =  107 bits (266), Expect = 4e-23
 Identities = 54/102 (52%), Positives = 70/102 (68%)
 Frame = -3

Query: 663  YSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAYG 484
            Y+  S  IQWFW++V+    E + R LQFVTGT ++P+ GF+ L G +GPQ+F I K  G
Sbjct: 769  YTKNSKQIQWFWQVVKEMDNEKRIRLLQFVTGTCRLPVGGFAELIGSNGPQKFCIDKV-G 827

Query: 483  STNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGFG 358
                LP +HTCFN+LDLP Y S +QL+E+LL AI E  EGFG
Sbjct: 828  KETWLPRSHTCFNRLDLPPYKSYEQLREKLLYAIEE-TEGFG 868

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>NEDD4_RAT (Q62940) E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-)|
          Length = 887

 Score =  105 bits (263), Expect = 9e-23
 Identities = 52/102 (50%), Positives = 70/102 (68%)
 Frame = -3

Query: 666  GYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAY 487
            GYS+   VI WFW+ V     E + R LQFVTGTS+VP+ GF+ L G +GPQ F + + +
Sbjct: 784  GYSLNHQVIHWFWKAVLMMDSEKRIRLLQFVTGTSRVPMNGFAELYGSNGPQSFTVEQ-W 842

Query: 486  GSTNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGF 361
            G+ + LP AHTCFN+LDLP Y S D+L ++L +AI E  +GF
Sbjct: 843  GTPDKLPRAHTCFNRLDLPPYESFDELWDKLQMAI-ENTQGF 883

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>NEDD4_MOUSE (P46935) E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) (Neural|
            precursor cell expressed developmentally down-regulated
            protein 4)
          Length = 887

 Score =  105 bits (262), Expect = 1e-22
 Identities = 52/102 (50%), Positives = 70/102 (68%)
 Frame = -3

Query: 666  GYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAY 487
            GYS+   VI WFW+ V     E + R LQFVTGTS+VP+ GF+ L G +GPQ F + + +
Sbjct: 784  GYSMNHQVIHWFWKAVWMMDSEKRIRLLQFVTGTSRVPMNGFAELYGSNGPQSFTVEQ-W 842

Query: 486  GSTNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGF 361
            G+ + LP AHTCFN+LDLP Y S D+L ++L +AI E  +GF
Sbjct: 843  GTPDKLPRAHTCFNRLDLPPYESFDELWDKLQMAI-ENTQGF 883

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>NEDD4_HUMAN (P46934) E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-)|
          Length = 1000

 Score =  104 bits (260), Expect = 2e-22
 Identities = 52/102 (50%), Positives = 69/102 (67%)
 Frame = -3

Query: 666  GYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAY 487
            GYS    VIQWFW+ V     E + R LQFVTGTS+VP+ GF+ L G +GPQ F + + +
Sbjct: 897  GYSANHQVIQWFWKAVLMMDSEKRIRLLQFVTGTSRVPMNGFAELYGSNGPQSFTVEQ-W 955

Query: 486  GSTNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGF 361
            G+   LP AHTCFN+LDLP Y S ++L ++L +AI E  +GF
Sbjct: 956  GTPEKLPRAHTCFNRLDLPPYESFEELWDKLQMAI-ENTQGF 996

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>SUDX_DROME (Q9Y0H4) E3 ubiquitin-protein ligase suppressor of deltex (EC|
            6.3.2.-)
          Length = 949

 Score =  104 bits (259), Expect = 3e-22
 Identities = 54/101 (53%), Positives = 66/101 (65%)
 Frame = -3

Query: 663  YSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAYG 484
            Y+  S  + WFW+ V+    E +AR LQFVTGT +VP+ GF+ L G +GPQRF I K  G
Sbjct: 848  YNRNSKQVVWFWQFVRETDNEKRARLLQFVTGTCRVPVGGFAELMGSNGPQRFCIEKV-G 906

Query: 483  STNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGF 361
                LP +HTCFN+LDLP Y S DQL E+L  AI E  EGF
Sbjct: 907  KETWLPRSHTCFNRLDLPPYKSYDQLVEKLTFAIEE-TEGF 946

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>WWP1_MOUSE (Q8BZZ3) NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW|
            domain-containing protein 1)
          Length = 918

 Score =  104 bits (259), Expect = 3e-22
 Identities = 54/102 (52%), Positives = 68/102 (66%)
 Frame = -3

Query: 663  YSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAYG 484
            Y+  S  I WFW+ V+    E + R LQFVTGT ++PL GF+ L G +GPQ+F I K  G
Sbjct: 817  YTRNSKQIIWFWQFVKETDNEVRMRLLQFVTGTCRLPLGGFAELMGSNGPQKFCIEKV-G 875

Query: 483  STNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGFG 358
                LP +HTCFN+LDLP Y S +QL+E+LL AI E  EGFG
Sbjct: 876  KDTWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEE-TEGFG 916

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>WWP1_HUMAN (Q9H0M0) NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW|
            domain-containing protein 1) (Atropin-1-interacting
            protein 5) (AIP5)
          Length = 922

 Score =  104 bits (259), Expect = 3e-22
 Identities = 54/102 (52%), Positives = 68/102 (66%)
 Frame = -3

Query: 663  YSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAYG 484
            Y+  S  I WFW+ V+    E + R LQFVTGT ++PL GF+ L G +GPQ+F I K  G
Sbjct: 821  YTRNSKQIIWFWQFVKETDNEVRMRLLQFVTGTCRLPLGGFAELMGSNGPQKFCIEKV-G 879

Query: 483  STNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGFG 358
                LP +HTCFN+LDLP Y S +QL+E+LL AI E  EGFG
Sbjct: 880  KDTWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEE-TEGFG 920

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>SMUF1_DROME (Q9V853) E3 ubiquitin-protein ligase Smurf1 (EC 6.3.2.-) (Smad|
            ubiquitination regulatory factor 1 homolog) (DSmurf)
            (Lethal with a checkpoint kinase protein)
          Length = 1061

 Score = 95.9 bits (237), Expect = 1e-19
 Identities = 47/93 (50%), Positives = 65/93 (69%), Gaps = 4/93 (4%)
 Frame = -3

Query: 642  IQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGIS---GPQRFQIH-KAYGSTN 475
            + WFW++V+ +S E +AR LQFVTG+S+VPL+GF ALQG +   GP+ F IH  A   T 
Sbjct: 962  VLWFWQVVESYSSEMRARLLQFVTGSSRVPLQGFRALQGSTGAVGPRLFTIHLTADVPTQ 1021

Query: 474  HLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHE 376
            +LP AHTCFN++DLP Y +   L ++L  A+ E
Sbjct: 1022 NLPKAHTCFNRIDLPPYETYQLLCDKLTQAVEE 1054

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>UBE3A_HUMAN (Q05086) Ubiquitin-protein ligase E3A (EC 6.3.2.-) (E6AP|
            ubiquitin-protein ligase) (Oncogenic protein-associated
            protein E6-AP) (Human papillomavirus E6-associated
            protein) (NY-REN-54 antigen)
          Length = 875

 Score = 88.2 bits (217), Expect = 2e-17
 Identities = 51/103 (49%), Positives = 65/103 (63%)
 Frame = -3

Query: 666  GYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAY 487
            GY+  S +I+ FWEIV  F+ E K  FLQF TGT + P+ G   L+ I       I K  
Sbjct: 779  GYTRDSVLIREFWEIVHSFTDEQKRLFLQFTTGTDRAPVGGLGKLKMI-------IAKNG 831

Query: 486  GSTNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGFG 358
              T  LP++HTCFN L LPEY+SK++L+ERLL AI  A +GFG
Sbjct: 832  PDTERLPTSHTCFNVLLLPEYSSKEKLKERLLKAITYA-KGFG 873

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>UBE3A_MOUSE (O08759) Ubiquitin-protein ligase E3A (EC 6.3.2.-) (Oncogenic|
            protein-associated protein E6-AP)
          Length = 885

 Score = 84.0 bits (206), Expect = 4e-16
 Identities = 50/103 (48%), Positives = 62/103 (60%)
 Frame = -3

Query: 666  GYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAY 487
            GY+  S VI+ FWEIV  F+ E K  FL F TGT + P+ G   L+ I       I K  
Sbjct: 789  GYTRESVVIREFWEIVHSFTDEQKRLFLLFTTGTDRAPVGGLGKLKMI-------IAKNG 841

Query: 486  GSTNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGFG 358
              T  LP++HTCFN L LPEY+SK++L  RLL AI  A +GFG
Sbjct: 842  PDTERLPTSHTCFNVLLLPEYSSKEKLNVRLLKAITYA-KGFG 883

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>K0317_MOUSE (Q8CHG5) Protein KIAA0317|
          Length = 823

 Score = 84.0 bits (206), Expect = 4e-16
 Identities = 46/96 (47%), Positives = 62/96 (64%)
 Frame = -3

Query: 645  VIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAYGSTNHLP 466
            V++WFW +V   ++E+ AR LQF TG+S++P  GF+AL        FQI  A  + + LP
Sbjct: 732  VMRWFWAVVSSLTQEELARLLQFTTGSSQLPPGGFAALC-----PSFQIIAA-PTHSTLP 785

Query: 465  SAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGFG 358
            +AHTCFNQL LP Y S +++   L LAI E  EGFG
Sbjct: 786  TAHTCFNQLCLPTYDSYEEVHRMLQLAISEGCEGFG 821

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>K0317_HUMAN (O15033) Protein KIAA0317|
          Length = 823

 Score = 84.0 bits (206), Expect = 4e-16
 Identities = 46/96 (47%), Positives = 62/96 (64%)
 Frame = -3

Query: 645  VIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAYGSTNHLP 466
            V++WFW +V   ++E+ AR LQF TG+S++P  GF+AL        FQI  A  + + LP
Sbjct: 732  VMRWFWTVVSSLTQEELARLLQFTTGSSQLPPGGFAALC-----PSFQIIAA-PTHSTLP 785

Query: 465  SAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGFG 358
            +AHTCFNQL LP Y S +++   L LAI E  EGFG
Sbjct: 786  TAHTCFNQLCLPTYDSYEEVHRMLQLAISEGCEGFG 821

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>HUL4_ASHGO (Q757T0) Probable ubiquitin-protein ligase HUL4 (EC 6.3.2.-) (HECT|
            ubiquitin ligase 4)
          Length = 839

 Score = 81.6 bits (200), Expect = 2e-15
 Identities = 38/104 (36%), Positives = 62/104 (59%)
 Frame = -3

Query: 666  GYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAY 487
            G+   SPV+QWFWEI+       + + L FVTG+ +VP  G + +        F+I +  
Sbjct: 743  GFDDNSPVVQWFWEILSEMEYPQQRKLLHFVTGSDRVPATGVTTIP-------FRISRIR 795

Query: 486  GSTNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGFGF 355
               + LP +HTCFN++ L EY  K+ L+ +L++A+ E ++G+GF
Sbjct: 796  SGADRLPLSHTCFNEICLHEYKDKETLRNKLIIALEE-SQGYGF 838

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>UBE3C_HUMAN (Q15386) Ubiquitin-protein ligase E3C (EC 6.3.2.-)|
          Length = 1083

 Score = 77.8 bits (190), Expect = 3e-14
 Identities = 44/102 (43%), Positives = 57/102 (55%)
 Frame = -3

Query: 666  GYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAY 487
            GYS   PVI+ FW +V+GF+ E+K + L+FVT  S+ PL GF  L        F IH   
Sbjct: 985  GYSADHPVIKVFWRVVEGFTDEEKRKLLKFVTSCSRPPLLGFKELY-----PAFCIHNGG 1039

Query: 486  GSTNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGF 361
                 LP+A TC N L LPE+  +  L+ +LL AI E   GF
Sbjct: 1040 SDLERLPTASTCMNLLKLPEFYDETLLRSKLLYAI-ECAAGF 1080

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>UBE3C_MOUSE (Q80U95) Ubiquitin-protein ligase E3C (EC 6.3.2.-)|
          Length = 1083

 Score = 77.4 bits (189), Expect = 4e-14
 Identities = 44/102 (43%), Positives = 57/102 (55%)
 Frame = -3

Query: 666  GYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAY 487
            GYS   PVI+ FW +V+GF+ E+K + L+FVT  S+ PL GF  L        F IH   
Sbjct: 985  GYSADHPVIKIFWRVVEGFTDEEKRKLLKFVTSCSRPPLLGFKELY-----PAFCIHNGG 1039

Query: 486  GSTNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGF 361
                 LP+A TC N L LPE+  +  L+ +LL AI E   GF
Sbjct: 1040 SDLERLPTASTCMNLLKLPEFYDEALLRSKLLYAI-ECAAGF 1080

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>HERC3_HUMAN (Q15034) HECT domain and RCC1-like domain protein 3|
          Length = 1050

 Score = 76.6 bits (187), Expect = 6e-14
 Identities = 40/101 (39%), Positives = 58/101 (57%)
 Frame = -3

Query: 663  YSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAYG 484
            YS   P ++ FWE    F  E K +FL F+TG+ ++P+ G ++LQ +       I     
Sbjct: 955  YSATHPTVKLFWETFHEFPLEKKKKFLLFLTGSDRIPIYGMASLQIV-------IQSTAS 1007

Query: 483  STNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGF 361
               +LP AHTC+N LDLP+Y+SK+ L  RL  A+ +  EGF
Sbjct: 1008 GEEYLPVAHTCYNLLDLPKYSSKEILSARLTQAL-DNYEGF 1047

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>HUL4_YEAST (P40985) Probable ubiquitin-protein ligase HUL4 (EC 6.3.2.-) (HECT|
            ubiquitin ligase 4)
          Length = 892

 Score = 74.3 bits (181), Expect = 3e-13
 Identities = 40/104 (38%), Positives = 65/104 (62%)
 Frame = -3

Query: 666  GYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAY 487
            G+S  S  + WFWEI++ +    + + LQFVT + ++P  G S +     P +  +  ++
Sbjct: 795  GFSDDSRAVCWFWEIIESWDYPLQKKLLQFVTASDRIPATGISTI-----PFKISLLGSH 849

Query: 486  GSTNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGFGF 355
             S + LP AHTCFN++ L  Y+SK +L+ +LL AI+E +EG+GF
Sbjct: 850  DS-DDLPLAHTCFNEICLWNYSSKKKLELKLLWAINE-SEGYGF 891

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>UFD4_YEAST (P33202) Ubiquitin fusion degradation protein 4 (UB fusion protein 4)|
          Length = 1483

 Score = 72.8 bits (177), Expect = 9e-13
 Identities = 43/107 (40%), Positives = 60/107 (56%), Gaps = 5/107 (4%)
 Frame = -3

Query: 666  GYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQI---H 496
            GY++ S +I  F  I+  F K ++  FLQF+TG+ K+P+ GF +L       +F +   H
Sbjct: 1379 GYTMDSSIIHDFISIISAFGKHERRLFLQFLTGSPKLPIGGFKSLN-----PKFTVVLKH 1433

Query: 495  KAYGST--NHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGF 361
               G T   +LPS  TC N L LP+YTSKD ++ RL  AI E    F
Sbjct: 1434 AEDGLTADEYLPSVMTCANYLKLPKYTSKDIMRSRLCQAIEEGAGAF 1480

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>HUL5_YEAST (P53119) Probable ubiquitin-protein ligase HUL5 (EC 6.3.2.-)|
          Length = 910

 Score = 72.4 bits (176), Expect = 1e-12
 Identities = 40/96 (41%), Positives = 53/96 (55%)
 Frame = -3

Query: 666  GYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAY 487
            GY      I  FWE++  F  E+K  FL+FVT   + PL+GF AL       +F I  A 
Sbjct: 812  GYKEEDQTIVDFWEVLNEFKFEEKLNFLKFVTSVPQAPLQGFKALD-----PKFGIRNAG 866

Query: 486  GSTNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIH 379
                 LP+A TC N L LP+Y +K  L+E+LL AI+
Sbjct: 867  TEKYRLPTASTCVNLLKLPDYRNKTILREKLLYAIN 902

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>TRIPC_HUMAN (Q14669) Thyroid receptor-interacting protein 12 (TRIP12)|
          Length = 1992

 Score = 72.4 bits (176), Expect = 1e-12
 Identities = 39/106 (36%), Positives = 62/106 (58%), Gaps = 4/106 (3%)
 Frame = -3

Query: 666  GYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAY 487
            GY+  S  +++ +EI+  F  E +  FLQFVTG+ ++P+ GF +L     P    + K +
Sbjct: 1888 GYTHDSRAVKFLFEILSSFDNEQQRLFLQFVTGSPRLPVGGFRSL----NPPLTIVRKTF 1943

Query: 486  GSTNH----LPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGF 361
             ST +    LPS  TC N L LP+Y+S + ++E+LL+A  E  + F
Sbjct: 1944 ESTENPDDFLPSVMTCVNYLKLPDYSSIEIMREKLLIAAREGQQSF 1989

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>YDE1_SCHPO (Q10435) Probable ubiquitin fusion degradation protein C12B10.01c|
          Length = 1647

 Score = 67.8 bits (164), Expect = 3e-11
 Identities = 38/102 (37%), Positives = 55/102 (53%)
 Frame = -3

Query: 666  GYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAY 487
            GY++ SP IQ    ++   + +++  FLQF+TG+ K+P+ GF+ L       R      Y
Sbjct: 1543 GYTMESPTIQRLLTLMSQMNFQEQRDFLQFITGSRKLPIGGFAGLNPPLTVVRRLNEPPY 1602

Query: 486  GSTNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGF 361
               ++LPS  TC N L LPEY+S + L  RL  AI E    F
Sbjct: 1603 VPDDYLPSVMTCVNYLKLPEYSSSEVLGSRLSKAILEGQGSF 1644

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>HERC2_HUMAN (O95714) HECT domain and RCC1-like domain-containing protein 2|
          Length = 4834

 Score = 66.6 bits (161), Expect = 6e-11
 Identities = 35/99 (35%), Positives = 57/99 (57%), Gaps = 3/99 (3%)
 Frame = -3

Query: 666  GYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVP--LEGFSALQGISGPQRFQIHK 493
            G   ++ +IQWFWE+++ FS  +++ FL+FV G +++P  +  F     +      Q+  
Sbjct: 4693 GIEPSASLIQWFWEVMESFSNTERSLFLRFVWGRTRLPRTIADFRGRDFV-----IQVLD 4747

Query: 492  AYGSTNH-LPSAHTCFNQLDLPEYTSKDQLQERLLLAIH 379
             Y   +H LP ++TCF  L LP Y+ K  L+E+L  AIH
Sbjct: 4748 KYNPPDHFLPESYTCFFLLKLPRYSCKQVLEEKLKYAIH 4786

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>HERC2_MOUSE (Q4U2R1) HECT domain and RCC1-like domain-containing protein 2|
          Length = 4836

 Score = 66.2 bits (160), Expect = 8e-11
 Identities = 34/99 (34%), Positives = 57/99 (57%), Gaps = 3/99 (3%)
 Frame = -3

Query: 666  GYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVP--LEGFSALQGISGPQRFQIHK 493
            G   ++ ++QWFWE+++ FS  +++ FL+FV G +++P  +  F     +      Q+  
Sbjct: 4695 GIEPSASLVQWFWEVMESFSNTERSLFLRFVWGRTRLPRTIADFRGRDFV-----IQVLD 4749

Query: 492  AYGSTNH-LPSAHTCFNQLDLPEYTSKDQLQERLLLAIH 379
             Y   +H LP ++TCF  L LP Y+ K  L+E+L  AIH
Sbjct: 4750 KYNPPDHFLPESYTCFFLLKLPRYSCKQVLEEKLKYAIH 4788

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>HECD1_HUMAN (Q9ULT8) E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing|
            protein 1) (E3 ligase for inhibin receptor) (EULIR)
          Length = 2612

 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 35/97 (36%), Positives = 53/97 (54%)
 Frame = -3

Query: 666  GYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAY 487
            GY+  SP    F  ++ G S +++  FLQF TG S +P  G + L     P+   + K  
Sbjct: 2514 GYTRDSPGFLRFVRVLCGMSSDERKAFLQFTTGCSTLPPGGLANLH----PRLTVVRKVD 2569

Query: 486  GSTNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHE 376
             +    PS +TC + L LPEY+S++ ++ERLL A  E
Sbjct: 2570 ATDASYPSVNTCVHYLKLPEYSSEEIMRERLLAATME 2606

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>HERC2_DROME (Q9VR91) HECT domain and RCC1-like domain-containing protein 2|
          Length = 4912

 Score = 60.5 bits (145), Expect = 5e-09
 Identities = 30/98 (30%), Positives = 56/98 (57%), Gaps = 2/98 (2%)
 Frame = -3

Query: 666  GYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVP--LEGFSALQGISGPQRFQIHK 493
            G+  +S ++ WFWE+++ F+ ++++ FL+FV G +++P  +  F     +      Q+ +
Sbjct: 4782 GFDPSSALVTWFWEVMEEFTNQERSLFLRFVWGRTRLPRTIADFRGRDFV-----LQVLE 4836

Query: 492  AYGSTNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIH 379
                 + LP ++TCF  L +P Y+ K  L E+L  AIH
Sbjct: 4837 KNPPDHFLPESYTCFFLLKMPRYSCKAVLLEKLKYAIH 4874

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>HYD_DROME (P51592) Ubiquitin--protein ligase hyd (EC 6.3.2.-) (Protein|
            hyperplastic discs)
          Length = 2885

 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 34/95 (35%), Positives = 54/95 (56%), Gaps = 2/95 (2%)
 Frame = -3

Query: 639  QWFWEIVQGFSKEDKARFLQFVTGTSKVPL--EGFSALQGISGPQRFQIHKAYGSTNHLP 466
            +WFW IV+  +  ++   + F TG+  +P   EGF  L  ++      I  A  S  HLP
Sbjct: 2798 KWFWSIVEKMNIMERQDLVYFWTGSPALPASEEGFQPLPSVT------IRPADDS--HLP 2849

Query: 465  SAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGF 361
            +A+TC ++L +P Y+SK  L+ ++L+AI   N GF
Sbjct: 2850 TANTCISRLYIPLYSSKSILRSKMLMAIKSKNFGF 2884

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>EDD1_MOUSE (Q80TP3) Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic|
            discs protein homolog)
          Length = 2792

 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 35/96 (36%), Positives = 53/96 (55%), Gaps = 3/96 (3%)
 Frame = -3

Query: 639  QWFWEIVQGFSKEDKARFLQFVTGTSKVPL--EGFSALQGIS-GPQRFQIHKAYGSTNHL 469
            +WFW IV+  S  ++   + F T +  +P   EGF  +  I+  P   Q         HL
Sbjct: 2705 RWFWSIVEKMSMTERQDLVYFWTSSPSLPASEEGFQPMPSITIRPPDDQ---------HL 2755

Query: 468  PSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGF 361
            P+A+TC ++L +P Y+SK  L+++LLLAI   N GF
Sbjct: 2756 PTANTCISRLYVPLYSSKQILKQKLLLAIKTKNFGF 2791

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>EDD1_HUMAN (O95071) Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic|
            discs protein homolog) (hHYD) (Progestin-induced protein)
          Length = 2799

 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 35/96 (36%), Positives = 53/96 (55%), Gaps = 3/96 (3%)
 Frame = -3

Query: 639  QWFWEIVQGFSKEDKARFLQFVTGTSKVPL--EGFSALQGIS-GPQRFQIHKAYGSTNHL 469
            +WFW IV+  S  ++   + F T +  +P   EGF  +  I+  P   Q         HL
Sbjct: 2712 RWFWSIVEKMSMTERQDLVYFWTSSPSLPASEEGFQPMPSITIRPPDDQ---------HL 2762

Query: 468  PSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGF 361
            P+A+TC ++L +P Y+SK  L+++LLLAI   N GF
Sbjct: 2763 PTANTCISRLYVPLYSSKQILKQKLLLAIKTKNFGF 2798

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>EDD1_RAT (Q62671) Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic|
            discs protein homolog) (100 kDa protein) (Fragment)
          Length = 920

 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 35/96 (36%), Positives = 53/96 (55%), Gaps = 3/96 (3%)
 Frame = -3

Query: 639  QWFWEIVQGFSKEDKARFLQFVTGTSKVPL--EGFSALQGIS-GPQRFQIHKAYGSTNHL 469
            +WFW IV+  S  ++   + F T +  +P   EGF  +  I+  P   Q         HL
Sbjct: 833  RWFWSIVERMSMTERQDLVYFWTSSPSLPASEEGFQPMPSITIRPPDDQ---------HL 883

Query: 468  PSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGF 361
            P+A+TC ++L +P Y+SK  L+++LLLAI   N GF
Sbjct: 884  PTANTCISRLYVPLYSSKQILKQKLLLAIKTKNFGF 919

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>HERC5_HUMAN (Q9UII4) HECT domain and RCC1-like domain-containing protein 5|
            (Cyclin-E-binding protein 1)
          Length = 1024

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 31/103 (30%), Positives = 58/103 (56%)
 Frame = -3

Query: 666  GYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAY 487
            GY+ + P I  FW+     + E+K +FL F+TGT ++ ++  + ++       F   +++
Sbjct: 929  GYNSSHPTIVMFWKAFHKLTLEEKKKFLVFLTGTDRLQMKDLNNMK-----ITFCCPESW 983

Query: 486  GSTNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGFG 358
               + +  A TCF+ L LP+Y++ + ++E L  AI+  N GFG
Sbjct: 984  NERDPI-RALTCFSVLFLPKYSTMETVEEALQEAINN-NRGFG 1024

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>GLMM_PHOLL (Q7MYY3) Phosphoglucosamine mutase (EC 5.4.2.10)|
          Length = 445

 Score = 30.4 bits (67), Expect = 5.0
 Identities = 17/50 (34%), Positives = 26/50 (52%), Gaps = 6/50 (12%)
 Frame = +3

Query: 81  QIVGVCLNSHSSLHILCSNLFAL------IMEDLSHFPTNMENLLVVTKA 212
           QI+   + +H SLH LCS +  L      +    SH P   EN++ +TK+
Sbjct: 347 QILSAMVRNHMSLHDLCSGMKLLPQVLVNVRFSGSHDPLKSENVINITKS 396

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>CENB2_HUMAN (Q15057) Centaurin-beta 2 (Cnt-b2)|
          Length = 778

 Score = 30.4 bits (67), Expect = 5.0
 Identities = 22/75 (29%), Positives = 33/75 (44%)
 Frame = -3

Query: 621 VQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAYGSTNHLPSAHTCFNQ 442
           +Q F KED  +F        KV  E  +AL   +  QR + H+   +TN L +   CF  
Sbjct: 109 LQNFVKEDLRKFKDAKKQFEKVSEEKENALVKNAQVQRNKQHEVEEATNILTATRKCFRH 168

Query: 441 LDLPEYTSKDQLQER 397
           + L      + LQ +
Sbjct: 169 IALDYVLQINVLQSK 183

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>MUT7_CAEEL (P34607) Probable exonuclease mut-7 (EC 3.1.-.-)|
          Length = 910

 Score = 30.4 bits (67), Expect = 5.0
 Identities = 17/44 (38%), Positives = 26/44 (59%), Gaps = 2/44 (4%)
 Frame = +1

Query: 436 VQLVKASMSRGKMVGAAVRLVYLEP--LWPRYSLKRTETLQRYL 561
           V ++KA   RGK  G ++ + YLE   +W + S + TE  Q+YL
Sbjct: 72  VDMMKAMPDRGKTSGQSLAVWYLEDFGVWLKESGQETELRQKYL 115

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>FBN3_HUMAN (Q75N90) Fibrillin-3 precursor|
          Length = 2809

 Score = 30.4 bits (67), Expect = 5.0
 Identities = 19/53 (35%), Positives = 24/53 (45%)
 Frame = +3

Query: 90   GVCLNSHSSLHILCSNLFALIMEDLSHFPTNMENLLVVTKADASCCQLVGSSR 248
            G CLN+  S H LC + F L  +  +   TN    L  T    +C  L GS R
Sbjct: 1901 GHCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFR 1953


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 106,312,940
Number of Sequences: 219361
Number of extensions: 2410826
Number of successful extensions: 5694
Number of sequences better than 10.0: 58
Number of HSP's better than 10.0 without gapping: 5446
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5649
length of database: 80,573,946
effective HSP length: 108
effective length of database: 56,882,958
effective search space used: 6484657212
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

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full-length cDNA and EST

Clone Information

BLAST Search Result