>IMB_DROME (O18388) Importin beta subunit (Karyopherin beta-4 subunit) (Protein|
            ketel)
          Length = 884

 Score = 62.4 bits (150), Expect = 9e-10
 Identities = 35/98 (35%), Positives = 55/98 (56%), Gaps = 6/98 (6%)
 Frame = -2

Query: 575  MPMLQGAAELLVVLDQNDEDMVDYGNQLRRGIFEAYSGILQGLKG------AKAQLMIPY 414
            + ML+ A+ L    D N+ DM +Y N+LR  I EAY+GI+QGLKG           M P+
Sbjct: 742  LDMLRVASNLQT--DANNFDMNEYINELRESILEAYTGIIQGLKGVDQTAHTDVMHMEPH 799

Query: 413  AGHLLQFTEAVYKDGSRDESVTKAAVAVLGDLADTLGP 300
              H++ F + + ++G   +S+  +A   +GDL  + GP
Sbjct: 800  LMHIISFIKRIAQEGDVSDSMLASAAGFIGDLCTSFGP 837

>IMB1_HUMAN (Q14974) Importin beta-1 subunit (Karyopherin beta-1 subunit)|
            (Nuclear factor P97) (Importin 90)
          Length = 876

 Score = 59.7 bits (143), Expect = 6e-09
 Identities = 38/102 (37%), Positives = 54/102 (52%), Gaps = 6/102 (5%)
 Frame = -2

Query: 566  LQGAAELLVVLDQNDEDMVDYGNQLRRGIFEAYSGILQGLKGAK------AQLMIPYAGH 405
            LQ A++  V  D++D DMVDY N+LR    EAY+GI+QGLKG +        L+ P    
Sbjct: 739  LQQASQAQV--DKSDYDMVDYLNELRESCLEAYTGIVQGLKGDQENVHPDVMLVQPRVEF 796

Query: 404  LLQFTEAVYKDGSRDESVTKAAVAVLGDLADTLGPISKDLFK 279
            +L F + +  D    + V   A  ++GDL    G   KD+ K
Sbjct: 797  ILSFIDHIAGDEDHTDGVVACAAGLIGDLCTAFG---KDVLK 835

>IMB1_RAT (P52296) Importin beta-1 subunit (Karyopherin beta-1 subunit)|
            (Nuclear factor P97)
          Length = 875

 Score = 59.3 bits (142), Expect = 8e-09
 Identities = 38/102 (37%), Positives = 54/102 (52%), Gaps = 6/102 (5%)
 Frame = -2

Query: 566  LQGAAELLVVLDQNDEDMVDYGNQLRRGIFEAYSGILQGLKGAK------AQLMIPYAGH 405
            LQ A++  V  D++D DMVDY N+LR    EAY+GI+QGLKG +        L+ P    
Sbjct: 738  LQQASQAQV--DKSDFDMVDYLNELRESCLEAYTGIVQGLKGDQENVHPDVMLVQPRVEF 795

Query: 404  LLQFTEAVYKDGSRDESVTKAAVAVLGDLADTLGPISKDLFK 279
            +L F + +  D    + V   A  ++GDL    G   KD+ K
Sbjct: 796  ILSFIDHIAGDEDHTDGVVACAAGLIGDLCTAFG---KDVLK 834

>IMB1_MOUSE (P70168) Importin beta-1 subunit (Karyopherin beta-1 subunit)|
            (Nuclear factor P97) (Pore targeting complex 97 kDa
            subunit) (PTAC97) (SCG)
          Length = 876

 Score = 59.3 bits (142), Expect = 8e-09
 Identities = 38/102 (37%), Positives = 54/102 (52%), Gaps = 6/102 (5%)
 Frame = -2

Query: 566  LQGAAELLVVLDQNDEDMVDYGNQLRRGIFEAYSGILQGLKGAK------AQLMIPYAGH 405
            LQ A++  V  D++D DMVDY N+LR    EAY+GI+QGLKG +        L+ P    
Sbjct: 739  LQQASQAQV--DKSDFDMVDYLNELRESCLEAYTGIVQGLKGDQENVHPDVMLVQPRVEF 796

Query: 404  LLQFTEAVYKDGSRDESVTKAAVAVLGDLADTLGPISKDLFK 279
            +L F + +  D    + V   A  ++GDL    G   KD+ K
Sbjct: 797  ILSFIDHIAGDEDHTDGVVACAAGLIGDLCTAFG---KDVLK 835

>IMB1_SCHPO (O13864) Importin beta-1 subunit (Karyopherin beta-1 subunit)|
           (Importin 95)
          Length = 863

 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 27/70 (38%), Positives = 41/70 (58%), Gaps = 1/70 (1%)
 Frame = -2

Query: 515 MVDYGNQLRRGIFEAYSGILQGLK-GAKAQLMIPYAGHLLQFTEAVYKDGSRDESVTKAA 339
           M+DY + LR GI EAY GI Q ++   +  L+ PY   +      +  D    ES+T+AA
Sbjct: 746 MIDYVDALRLGIVEAYVGITQAVRTDNRLDLIQPYVHSMFTLLNMITADPECSESLTRAA 805

Query: 338 VAVLGDLADT 309
           + +LGDLA++
Sbjct: 806 LGLLGDLAES 815

>IMB1_YEAST (Q06142) Importin beta-1 subunit (Karyopherin beta-1 subunit)|
            (Importin 95)
          Length = 861

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 27/112 (24%), Positives = 55/112 (49%), Gaps = 5/112 (4%)
 Frame = -2

Query: 518  DMVDYGNQLRRGIFEAYSGILQGLKGAKAQLMIPYAGHLLQFTEAVYKDGS--RDESVTK 345
            + +DY  ++   + +AY GI+ GL   K + + PY G + QF   V +D     +++ ++
Sbjct: 742  EALDYQIKVLEAVLDAYVGIVAGLHD-KPEALFPYVGTIFQFIAQVAEDPQLYSEDATSR 800

Query: 344  AAVAVLGDLADTLGPISKDLFKSHLFHVEFLRECLD---LDDEVRETASWTQ 198
            AAV ++GD+A      S   F    + +++++            ++TA W +
Sbjct: 801  AAVGLIGDIAAMFPDGSIKQFYGQDWVIDYIKRTRSGQLFSQATKDTARWAR 852

>SPD5_CAEEL (P91349) Spindle-defective protein 5|
          Length = 1198

 Score = 35.4 bits (80), Expect = 0.12
 Identities = 29/106 (27%), Positives = 47/106 (44%)
 Frame = -2

Query: 536 LDQNDEDMVDYGNQLRRGIFEAYSGILQGLKGAKAQLMIPYAGHLLQFTEAVYKDGSRDE 357
           LD     + D  N   R   EA +G  QG+ GA    M+P +  ++         G+  E
Sbjct: 236 LDDQSARLADSENV--RAQLEAATG--QGILGAAGNAMVPNSTFMI---------GNGRE 282

Query: 356 SVTKAAVAVLGDLADTLGPISKDLFKSHLFHVEFLRECLDLDDEVR 219
           S T+  +  + DL   L    K+  K+    VE++ +C  L+ E+R
Sbjct: 283 SQTRDQLNYIDDLETKLADAKKENDKARQALVEYMNKCSKLEHEIR 328

>YL126_MIMIV (Q5UPK2) Putative F-box protein L126|
          Length = 255

 Score = 34.7 bits (78), Expect = 0.21
 Identities = 17/40 (42%), Positives = 22/40 (55%)
 Frame = +2

Query: 338 RRLLSRSHPCSHLCRQLQ*IAIDGLHKVSSAELLRPLDPV 457
           + L++ SH CSH C Q + I  D L  V  AEL  P  P+
Sbjct: 17  KELIACSHACSHACSQWRRICSDKLLWVQKAELFGPESPI 56

>RPOC2_CYACA (Q9TM34) DNA-directed RNA polymerase beta'' chain (EC 2.7.7.6)|
           (PEP) (Plastid-encoded RNA polymerase beta'' subunit)
           (RNA polymerase beta'' subunit)
          Length = 1269

 Score = 29.6 bits (65), Expect = 6.7
 Identities = 21/80 (26%), Positives = 37/80 (46%), Gaps = 10/80 (12%)
 Frame = -2

Query: 539 VLDQNDEDMVDYGNQLRRGIFEAYSGILQGLKG--------AKAQLMIPYAGHLLQFTEA 384
           +L  N  D V+   ++ +G+F   SG+L+ +K          K  ++ P + +L  FT  
Sbjct: 646 ILLANSGDYVNKNTEIAKGVFCKCSGLLEIIKSNNIIKEIIIKPGVVYPVSNNLSTFTNK 705

Query: 383 VYKDGSR--DESVTKAAVAV 330
           ++  G +  D  VT   V V
Sbjct: 706 IFYPGEKIIDNIVTNKIVYV 725

>Y1264_MYCTU (Q11055) Hypothetical protein Rv1264/MT1302|
          Length = 397

 Score = 29.6 bits (65), Expect = 6.7
 Identities = 13/56 (23%), Positives = 31/56 (55%), Gaps = 2/56 (3%)
 Frame = -2

Query: 422 IPYAGHLLQFT--EAVYKDGSRDESVTKAAVAVLGDLADTLGPISKDLFKSHLFHV 261
           + +A   +++T  EA+ + G+ +  + K + A++  +   LGP+ +D+    L H+
Sbjct: 138 LSHAAEAMRYTALEAIMRPGATELDIAKGSQALVSQIVPLLGPMIQDMLFMQLRHM 193

>OSPA7_BORBU (Q04968) Outer surface protein A precursor (OSPA)|
          Length = 272

 Score = 29.6 bits (65), Expect = 6.7
 Identities = 20/61 (32%), Positives = 35/61 (57%), Gaps = 9/61 (14%)
 Frame = -2

Query: 467 SGILQGLKGAKAQLMIPYAGHLLQFT-EAVYKDG--------SRDESVTKAAVAVLGDLA 315
           SGIL+G+K  K+++ +  A  L + T E + +DG        S+D+S T+A     G+L+
Sbjct: 73  SGILEGVKADKSKVKLTVADDLSKTTLEVLKEDGTVVSRKVTSKDKSTTEAKFNEKGELS 132

Query: 314 D 312
           +
Sbjct: 133 E 133

>MLL4_HUMAN (Q9UMN6) Myeloid/lymphoid or mixed-lineage leukemia protein 4|
           (Trithorax homolog 2)
          Length = 2715

 Score = 29.3 bits (64), Expect = 8.7
 Identities = 16/48 (33%), Positives = 23/48 (47%)
 Frame = +2

Query: 422 SSAELLRPLDPVVCQSMPQKFPV*AGYHNQPYPRHFDPKQQEAQPPLE 565
           + A+LL+PL  +  Q +PQ  P        P P+   P   +  PPLE
Sbjct: 733 TQAQLLQPLQALQTQLLPQALP-------PPQPQLQPPPSPQQMPPLE 773

>CSN12_YARLI (Q6C1L4) COP9 signalosome complex subunit 12|
          Length = 396

 Score = 29.3 bits (64), Expect = 8.7
 Identities = 18/70 (25%), Positives = 34/70 (48%), Gaps = 1/70 (1%)
 Frame = -2

Query: 365 RDESVTKAAVAVLGDLADTLGPISKDLFKSHLFHVEFLRECLDL-DDEVRETASWTQGMI 189
           R  +++K+ + V+  ++  L P++    +SH     + R  L L DD+V +  +W    +
Sbjct: 173 RKRNMSKSVIKVVESMSRDLPPLAS-YPRSHTCTYSYYRGVLSLMDDDVEQAQNWLTQAL 231

Query: 188 NQAIVS*TRN 159
           NQ     T N
Sbjct: 232 NQCFYKSTDN 241

>SRBS1_MOUSE (Q62417) Sorbin and SH3 domain-containing protein 1 (Ponsin)|
            (c-Cbl-associated protein) (CAP) (SH3 domain protein 5)
            (SH3P12)
          Length = 1290

 Score = 29.3 bits (64), Expect = 8.7
 Identities = 16/33 (48%), Positives = 18/33 (54%), Gaps = 1/33 (3%)
 Frame = +2

Query: 284  TDP*RLAQVCPQDPPGQQRRLL-SRSHPCSHLC 379
            + P R A V PQ P  QQRR+   RS P   LC
Sbjct: 1200 SSPSRSATVSPQQPQAQQRRVTPDRSQPSLDLC 1232

>UVRC_STAS1 (Q49WR3) UvrABC system protein C (Protein uvrC) (Excinuclease ABC|
           subunit C)
          Length = 595

 Score = 29.3 bits (64), Expect = 8.7
 Identities = 22/61 (36%), Positives = 32/61 (52%), Gaps = 1/61 (1%)
 Frame = -2

Query: 461 ILQGLKGAKAQLMIPYAGHLLQFT-EAVYKDGSRDESVTKAAVAVLGDLADTLGPISKDL 285
           I+Q LKG K   M+  A H  + T E  ++  ++DES T  A+  LGD+     PI  + 
Sbjct: 328 IVQPLKGKKKD-MVDLANHNAEVTLENKFELIAKDESRTVKAIEELGDVMGIQTPIRIEA 386

Query: 284 F 282
           F
Sbjct: 387 F 387

>JHD3C_MOUSE (Q8VCD7) JmjC domain-containing histone demethylation protein 3C|
           (EC 1.14.11.-) (Jumonji domain-containing protein 2C)
          Length = 1054

 Score = 29.3 bits (64), Expect = 8.7
 Identities = 14/34 (41%), Positives = 20/34 (58%)
 Frame = -2

Query: 287 LFKSHLFHVEFLRECLDLDDEVRETASWTQGMIN 186
           L K  +   E L E L +D+EV ET SW + +I+
Sbjct: 584 LVKQQVASDEELPEVLSIDEEVEETESWAKPLIH 617


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 87,344,686
Number of Sequences: 219361
Number of extensions: 1801684
Number of successful extensions: 4882
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 4756
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4877
length of database: 80,573,946
effective HSP length: 106
effective length of database: 57,321,680
effective search space used: 5044307840
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)