ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | rbags17j23 |
|---|---|
| Clone Library Name | barley_pub |
>METB_ARATH (P55217) Cystathionine gamma-synthase, chloroplast precursor (EC| 2.5.1.48) (CGS) (O-succinylhomoserine (thiol)-lyase) Length = 563 Score = 315 bits (806), Expect = 1e-85 Identities = 149/203 (73%), Positives = 176/203 (86%), Gaps = 1/203 (0%) Frame = -2 Query: 654 INQKALTLGADIVVHSATKYIAGHNDVIGGCISGRGELVSKVRIYHHVVGGVLNPNASYL 475 +NQKAL LGAD+VVHSATKYI GHNDV+ GCI G +LVS++R HHV+GG LNPNA+YL Sbjct: 361 LNQKALALGADLVVHSATKYIGGHNDVLAGCICGSLKLVSEIRNLHHVLGGTLNPNAAYL 420 Query: 474 ILRGMKTLHLRVQCQNNTALRMAQFLEEHPKIARVYYPGLPSHPEHHIAKSQMTGFGGVV 295 I+RGMKTLHLRVQ QN+TA RMA+ LE HPK++ VYYPGLPSHPEH +AK QMTGFGGVV Sbjct: 421 IIRGMKTLHLRVQQQNSTAFRMAEILEAHPKVSHVYYPGLPSHPEHELAKRQMTGFGGVV 480 Query: 294 SFEVDGDFDSTRRFIDSVKIPYHAPSFGGCESIIDQPAIMSYWD-SKEQRDIYGIKDNLI 118 SFE+DGD ++T +F+DS+KIPY APSFGGCESI+DQPAIMSYWD +E+R YGIKDNL+ Sbjct: 481 SFEIDGDIETTIKFVDSLKIPYIAPSFGGCESIVDQPAIMSYWDLPQEERLKYGIKDNLV 540 Query: 117 RFSIGVEDFGDLKNDIVQALDKI 49 RFS GVEDF D+K DI+QAL+ I Sbjct: 541 RFSFGVEDFEDVKADILQALEAI 563
>METB_HELPY (P56069) Cystathionine gamma-synthase (EC 2.5.1.48) (CGS)| (O-succinylhomoserine (thiol)-lyase) Length = 380 Score = 183 bits (465), Expect = 3e-46 Identities = 92/202 (45%), Positives = 133/202 (65%), Gaps = 2/202 (0%) Frame = -2 Query: 648 QKALTLGADIVVHSATKYIAGHNDVIGGCISGRGE-LVSKVRIYHHVVGGVLNPNASYLI 472 Q L LGADIV HS TKY+ GH+DV+ G ++ E L ++ + + +GGVL P S+L+ Sbjct: 179 QNPLLLGADIVAHSGTKYLGGHSDVVAGLVTTNNEALAQEIAFFQNAIGGVLGPQDSWLL 238 Query: 471 LRGMKTLHLRVQCQNNTALRMAQFLEEHPKIARVYYPGLPSHPEHHIAKSQMTGFGGVVS 292 RG+KTL LR++ AL +A+FLE+HPK+ RVYYPGLP+HP + +AK QM GF G++S Sbjct: 239 QRGIKTLGLRMEAHQKNALCVAEFLEKHPKVERVYYPGLPTHPNYELAKKQMRGFSGMLS 298 Query: 291 FEVDGDFDSTRRFIDSVKIPYHAPSFGGCESIIDQPAIMSY-WDSKEQRDIYGIKDNLIR 115 F + D ++ F++S+K+ S GG ES++ PA M++ K QR+ GI+D L+R Sbjct: 299 FTLKNDSEAV-AFVESLKLFILGESLGGVESLVGIPAFMTHACIPKTQREAAGIRDGLVR 357 Query: 114 FSIGVEDFGDLKNDIVQALDKI 49 S+G+E DL D+ QA KI Sbjct: 358 LSVGIEHEQDLLEDLEQAFAKI 379
>METC_LACLC (P0A4K3) Cystathionine beta-lyase (EC 4.4.1.8) (CBL)| (Beta-cystathionase) (Cysteine lyase) Length = 380 Score = 179 bits (453), Expect = 8e-45 Identities = 93/201 (46%), Positives = 137/201 (68%), Gaps = 2/201 (0%) Frame = -2 Query: 648 QKALTLGADIVVHSATKYIAGHNDVIGGCISGRG-ELVSKVRIYHHVVGGVLNPNASYLI 472 Q+ + LGADIV+HSATKY+ GH+DV+ G ++ EL S++ + +G VL P S+L+ Sbjct: 180 QQPIALGADIVLHSATKYLGGHSDVVAGLVTTNSKELASEIGFLQNSIGAVLGPQDSWLV 239 Query: 471 LRGMKTLHLRVQCQNNTALRMAQFLEEHPKIARVYYPGLPSHPEHHIAKSQMTGFGGVVS 292 RG+KTL LR++ + A ++A+FLE +++VYYPGL SHP H IAK QM+ FGG++S Sbjct: 240 QRGIKTLALRMEAHSANAQKIAEFLETSKAVSKVYYPGLNSHPGHEIAKKQMSAFGGMIS 299 Query: 291 FEVDGDFDSTRRFIDSVKIPYHAPSFGGCESIIDQPAIMSYWD-SKEQRDIYGIKDNLIR 115 FE+ D ++ + F++++ A S GG ES+I+ PA+M++ KE R+ GIKD LIR Sbjct: 300 FELT-DENAVKDFVENLSYFTLAESLGGVESLIEVPAVMTHASIPKELREEIGIKDGLIR 358 Query: 114 FSIGVEDFGDLKNDIVQALDK 52 S+GVE DL DI +AL+K Sbjct: 359 LSVGVEAIEDLLTDIKEALEK 379
>METC_LACLA (P0A4K2) Cystathionine beta-lyase (EC 4.4.1.8) (CBL)| (Beta-cystathionase) (Cysteine lyase) Length = 380 Score = 179 bits (453), Expect = 8e-45 Identities = 93/201 (46%), Positives = 137/201 (68%), Gaps = 2/201 (0%) Frame = -2 Query: 648 QKALTLGADIVVHSATKYIAGHNDVIGGCISGRG-ELVSKVRIYHHVVGGVLNPNASYLI 472 Q+ + LGADIV+HSATKY+ GH+DV+ G ++ EL S++ + +G VL P S+L+ Sbjct: 180 QQPIALGADIVLHSATKYLGGHSDVVAGLVTTNSKELASEIGFLQNSIGAVLGPQDSWLV 239 Query: 471 LRGMKTLHLRVQCQNNTALRMAQFLEEHPKIARVYYPGLPSHPEHHIAKSQMTGFGGVVS 292 RG+KTL LR++ + A ++A+FLE +++VYYPGL SHP H IAK QM+ FGG++S Sbjct: 240 QRGIKTLALRMEAHSANAQKIAEFLETSKAVSKVYYPGLNSHPGHEIAKKQMSAFGGMIS 299 Query: 291 FEVDGDFDSTRRFIDSVKIPYHAPSFGGCESIIDQPAIMSYWD-SKEQRDIYGIKDNLIR 115 FE+ D ++ + F++++ A S GG ES+I+ PA+M++ KE R+ GIKD LIR Sbjct: 300 FELT-DENAVKDFVENLSYFTLAESLGGVESLIEVPAVMTHASIPKELREEIGIKDGLIR 358 Query: 114 FSIGVEDFGDLKNDIVQALDK 52 S+GVE DL DI +AL+K Sbjct: 359 LSVGVEAIEDLLTDIKEALEK 379
>METB_HELPJ (Q9ZMW7) Cystathionine gamma-synthase (EC 2.5.1.48) (CGS)| (O-succinylhomoserine (thiol)-lyase) Length = 380 Score = 177 bits (449), Expect = 2e-44 Identities = 90/202 (44%), Positives = 131/202 (64%), Gaps = 2/202 (0%) Frame = -2 Query: 648 QKALTLGADIVVHSATKYIAGHNDVIGGCISGRGE-LVSKVRIYHHVVGGVLNPNASYLI 472 Q L LG DIV H+ TKY+ GH+DV+ G ++ E L + + + +GGVL S+L+ Sbjct: 179 QNPLLLGTDIVAHNGTKYLGGHSDVVAGLVTTNNEALAQEFDFFQNAIGGVLGLQDSWLL 238 Query: 471 LRGMKTLHLRVQCQNNTALRMAQFLEEHPKIARVYYPGLPSHPEHHIAKSQMTGFGGVVS 292 RG+KTL LR++ AL +A+FLE+HPK+ RVYYPGLP+HP H +AK+QM GF G+ S Sbjct: 239 QRGIKTLGLRMEAHQKNALCVAEFLEKHPKVERVYYPGLPTHPNHELAKAQMRGFSGMFS 298 Query: 291 FEVDGDFDSTRRFIDSVKIPYHAPSFGGCESIIDQPAIMSY-WDSKEQRDIYGIKDNLIR 115 F + D ++ F++S+K+ S GG ES++ PA+M++ K QR+ GI+D L+R Sbjct: 299 FTLKNDSEAV-AFVESLKLFILGESLGGVESLVGIPALMTHACIPKAQREAAGIRDGLVR 357 Query: 114 FSIGVEDFGDLKNDIVQALDKI 49 S+G+E DL D+ QA KI Sbjct: 358 LSVGIEHEQDLLEDLDQAFAKI 379
>METZ_PSEAE (P55218) O-succinylhomoserine sulfhydrylase (EC 2.5.1.-) (OSH| sulfhydrylase) Length = 403 Score = 169 bits (428), Expect = 7e-42 Identities = 88/198 (44%), Positives = 129/198 (65%), Gaps = 1/198 (0%) Frame = -2 Query: 648 QKALTLGADIVVHSATKYIAGHNDVIGGCISGRGELVSKVRIYHHVVGGVLNPNASYLIL 469 Q+ L LGAD+V+HSATKYI G +GG ++GRGE + +V + G L+P ++L L Sbjct: 203 QQPLKLGADVVIHSATKYIDGQGRGMGGVVAGRGEQMKEVVGFLRTAGPTLSPFNAWLFL 262 Query: 468 RGMKTLHLRVQCQNNTALRMAQFLEEHPKIARVYYPGLPSHPEHHIAKSQMTGFGGVVSF 289 +G++TL +R+Q + +AL +A++LE P I RVYY GLPSHP+H +A+ Q +GFG VVSF Sbjct: 263 KGLETLRIRMQAHSASALALAEWLERQPGIERVYYAGLPSHPQHELARRQQSGFGAVVSF 322 Query: 288 EVDGDFDSTRRFIDSVKIPYHAPSFGGCESIIDQPAIMSYWD-SKEQRDIYGIKDNLIRF 112 +V G D+ RFID+ ++ + G ++ I PA S+ S E R GI D+LIR Sbjct: 323 DVKGGRDAAWRFIDATRMVSITTNLGDTKTTIAHPATTSHGRLSPEDRARAGIGDSLIRV 382 Query: 111 SIGVEDFGDLKNDIVQAL 58 ++G+ED DLK D+ + L Sbjct: 383 AVGLEDLDDLKADMARGL 400
>CGL_MACFA (Q60HG7) Cystathionine gamma-lyase (EC 4.4.1.1)| (Gamma-cystathionase) Length = 405 Score = 165 bits (418), Expect = 1e-40 Identities = 88/199 (44%), Positives = 128/199 (64%), Gaps = 2/199 (1%) Frame = -2 Query: 648 QKALTLGADIVVHSATKYIAGHNDVIGGCISGRGE-LVSKVRIYHHVVGGVLNPNASYLI 472 Q+ L LGADI + SATKY+ GH+DV+ G +S E L +++R + +G V +P YL Sbjct: 196 QRPLALGADICMCSATKYMNGHSDVVMGLVSVNCERLHNRLRFLQNSLGAVPSPLDCYLC 255 Query: 471 LRGMKTLHLRVQCQNNTALRMAQFLEEHPKIARVYYPGLPSHPEHHIAKSQMTGFGGVVS 292 RG+KTLH+R++ + +AQFLE +P + +V YPGLPSHP+H +AK Q TG G+++ Sbjct: 256 NRGLKTLHVRMEKHFKNGMAVAQFLESNPGVEKVIYPGLPSHPQHELAKRQCTGCTGMIT 315 Query: 291 FEVDGDFDSTRRFIDSVKIPYHAPSFGGCESIIDQPAIMSYWD-SKEQRDIYGIKDNLIR 115 F + G F+ ++K+ A S GG ES+++ PAIM++ K RD+ GI D LIR Sbjct: 316 FYIKGTLQHAEIFLKNLKLFTLAESLGGFESLVELPAIMTHASVPKNDRDVLGISDTLIR 375 Query: 114 FSIGVEDFGDLKNDIVQAL 58 S+G+ED DL D+ QAL Sbjct: 376 LSVGLEDEKDLLEDLDQAL 394
>CGL_HUMAN (P32929) Cystathionine gamma-lyase (EC 4.4.1.1)| (Gamma-cystathionase) Length = 405 Score = 163 bits (413), Expect = 4e-40 Identities = 88/199 (44%), Positives = 127/199 (63%), Gaps = 2/199 (1%) Frame = -2 Query: 648 QKALTLGADIVVHSATKYIAGHNDVIGGCISGRGE-LVSKVRIYHHVVGGVLNPNASYLI 472 Q+ L LGADI ++SATKY+ GH+DV+ G +S E L +++R + +G V +P YL Sbjct: 196 QRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCYLC 255 Query: 471 LRGMKTLHLRVQCQNNTALRMAQFLEEHPKIARVYYPGLPSHPEHHIAKSQMTGFGGVVS 292 RG+KTLH+R++ + +AQFLE +P + +V YPGLPSHP+H + K Q TG G+V+ Sbjct: 256 NRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVT 315 Query: 291 FEVDGDFDSTRRFIDSVKIPYHAPSFGGCESIIDQPAIMSYWD-SKEQRDIYGIKDNLIR 115 F + G F+ ++K+ A S GG ES+ + PAIM++ K RD+ GI D LIR Sbjct: 316 FYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIR 375 Query: 114 FSIGVEDFGDLKNDIVQAL 58 S+G+ED DL D+ QAL Sbjct: 376 LSVGLEDEEDLLEDLDQAL 394
>CGL_CAEEL (P55216) Putative cystathionine gamma-lyase (EC 4.4.1.1)| (Gamma-cystathionase) Length = 392 Score = 162 bits (410), Expect = 8e-40 Identities = 84/199 (42%), Positives = 125/199 (62%), Gaps = 2/199 (1%) Frame = -2 Query: 648 QKALTLGADIVVHSATKYIAGHNDVI-GGCISGRGELVSKVRIYHHVVGGVLNPNASYLI 472 Q+ ++LGAD+VVHS TKYI GH+DV+ G I+ E + VG V +P +L+ Sbjct: 187 QRPISLGADVVVHSITKYINGHSDVVMGAVITDNDEFQQHLFFMQLAVGAVPSPFDCFLV 246 Query: 471 LRGMKTLHLRVQCQNNTALRMAQFLEEHPKIARVYYPGLPSHPEHHIAKSQMTGFGGVVS 292 RG+KTLH+R++ AL +A++LE + +I V YP LPSHP+H + + Q G G++S Sbjct: 247 NRGLKTLHIRMRAHYENALAVAKYLEANDRIESVLYPALPSHPQHEVHEKQTKGMSGMIS 306 Query: 291 FEVDGDFDSTRRFIDSVKIPYHAPSFGGCESIIDQPAIMSYWD-SKEQRDIYGIKDNLIR 115 F + G+ +R F+ ++K+ A S GG ES+ + P+IM++ E R + GI DNLIR Sbjct: 307 FYLKGELQESRAFLSALKVFTLAESLGGYESLAELPSIMTHASVPAETRIVLGITDNLIR 366 Query: 114 FSIGVEDFGDLKNDIVQAL 58 S+G+ED DL D+ QAL Sbjct: 367 ISVGIEDLDDLVADLDQAL 385
>METB_MYCLE (P46807) Cystathionine gamma-synthase (EC 2.5.1.48) (CGS)| (O-succinylhomoserine (thiol)-lyase) Length = 388 Score = 159 bits (403), Expect = 5e-39 Identities = 85/199 (42%), Positives = 123/199 (61%), Gaps = 1/199 (0%) Frame = -2 Query: 648 QKALTLGADIVVHSATKYIAGHNDVIGGC-ISGRGELVSKVRIYHHVVGGVLNPNASYLI 472 Q+ L LGAD+V+HS TKYI GH+DV+GG ++ EL + G V +P +YL Sbjct: 192 QQPLMLGADVVLHSTTKYIGGHSDVVGGALVTNDEELDQAFGFLQNGAGAVPSPFDAYLT 251 Query: 471 LRGMKTLHLRVQCQNNTALRMAQFLEEHPKIARVYYPGLPSHPEHHIAKSQMTGFGGVVS 292 +RG+KTL LR+Q N A+ +A+FL HP ++ V YPGLPSHP H +A QM GFGG+VS Sbjct: 252 MRGLKTLVLRMQRHNENAITVAEFLAGHPSVSAVLYPGLPSHPGHEVAARQMRGFGGMVS 311 Query: 291 FEVDGDFDSTRRFIDSVKIPYHAPSFGGCESIIDQPAIMSYWDSKEQRDIYGIKDNLIRF 112 + + + K+ A S GG ES+I+QP+ M++ + + + D+L+R Sbjct: 312 LRMRAGRLAAQDLCARTKVFTLAESLGGVESLIEQPSAMTHASTTGSQ--LEVPDDLVRL 369 Query: 111 SIGVEDFGDLKNDIVQALD 55 S+G+ED GDL D+ QAL+ Sbjct: 370 SVGIEDVGDLLCDLKQALN 388
>MEGL_PSEPU (P13254) Methionine gamma-lyase (EC 4.4.1.11) (L-methioninase)| Length = 398 Score = 159 bits (403), Expect = 5e-39 Identities = 81/200 (40%), Positives = 131/200 (65%), Gaps = 3/200 (1%) Frame = -2 Query: 648 QKALTLGADIVVHSATKYIAGHNDVIGGCISGRGELVSKVRIY--HHVVGGVLNPNASYL 475 Q+ L LGAD+VVHSATKY++GH D+ G + G LV ++R+ + G VL+P+ + L Sbjct: 195 QRPLELGADLVVHSATKYLSGHGDITAGIVVGSQALVDRIRLQGLKDMTGAVLSPHDAAL 254 Query: 474 ILRGMKTLHLRVQCQNNTALRMAQFLEEHPKIARVYYPGLPSHPEHHIAKSQMTGFGGVV 295 ++RG+KTL+LR+ A +A+FL P++ ++YPGL S P++ +A+ QM+ GG++ Sbjct: 255 LMRGIKTLNLRMDRHCANAQVLAEFLARQPQVELIHYPGLASFPQYTLARQQMSQPGGMI 314 Query: 294 SFEVDGDFDSTRRFIDSVKIPYHAPSFGGCESIIDQPAIMSYWD-SKEQRDIYGIKDNLI 118 +FE+ G + RRF++++++ A S G ES+ PA M++ + E+R YGI + L+ Sbjct: 315 AFELKGGIGAGRRFMNALQLFSRAVSLGDAESLAQHPASMTHSSYTPEERAHYGISEGLV 374 Query: 117 RFSIGVEDFGDLKNDIVQAL 58 R S+G+ED DL D+ QAL Sbjct: 375 RLSVGLEDIDDLLADVQQAL 394
>CGL_RAT (P18757) Cystathionine gamma-lyase (EC 4.4.1.1)| (Gamma-cystathionase) (Probasin-related antigen) (PRB-RA) Length = 398 Score = 159 bits (401), Expect = 9e-39 Identities = 86/199 (43%), Positives = 126/199 (63%), Gaps = 2/199 (1%) Frame = -2 Query: 648 QKALTLGADIVVHSATKYIAGHNDVIGGCISGRGE-LVSKVRIYHHVVGGVLNPNASYLI 472 Q+ L LGADI + SATKY+ GH+DV+ G +S + L ++R + +G V +P YL Sbjct: 195 QRPLALGADICMCSATKYMNGHSDVVMGLVSVTSDDLNERLRFLQNSLGAVPSPFDCYLC 254 Query: 471 LRGMKTLHLRVQCQNNTALRMAQFLEEHPKIARVYYPGLPSHPEHHIAKSQMTGFGGVVS 292 RG+KTL +R++ + +A+FLE +P++ +V YPGLPSHP+H +AK Q TG G+VS Sbjct: 255 CRGLKTLQIRMEKHFRNGMAVARFLESNPRVEKVIYPGLPSHPQHELAKRQCTGCPGMVS 314 Query: 291 FEVDGDFDSTRRFIDSVKIPYHAPSFGGCESIIDQPAIMSYWDSKEQ-RDIYGIKDNLIR 115 F + G + F+ ++K+ A S GG ES+ + PAIM++ E+ R GI D LIR Sbjct: 315 FYIKGTLQHAQVFLKNIKLFALAESLGGYESLAELPAIMTHASVPEKDRATLGISDTLIR 374 Query: 114 FSIGVEDFGDLKNDIVQAL 58 S+G+ED DL D+ QAL Sbjct: 375 LSVGLEDEKDLLEDLGQAL 393
>CGL_MOUSE (Q8VCN5) Cystathionine gamma-lyase (EC 4.4.1.1)| (Gamma-cystathionase) Length = 398 Score = 157 bits (397), Expect = 3e-38 Identities = 85/199 (42%), Positives = 127/199 (63%), Gaps = 2/199 (1%) Frame = -2 Query: 648 QKALTLGADIVVHSATKYIAGHNDVIGGCIS-GRGELVSKVRIYHHVVGGVLNPNASYLI 472 Q+ L LGADI + SATKY+ GH+DV+ G +S +L S++R + +G V +P YL Sbjct: 195 QRPLALGADICMCSATKYMNGHSDVVMGLVSVNSDDLNSRLRFLQNSLGAVPSPFDCYLC 254 Query: 471 LRGMKTLHLRVQCQNNTALRMAQFLEEHPKIARVYYPGLPSHPEHHIAKSQMTGFGGVVS 292 RG+KTL +R++ + +A+FLE +P++ +V YPGLPSHP+H +AK Q +G G+VS Sbjct: 255 CRGLKTLQVRMEKHFKNGMAVARFLETNPRVEKVVYPGLPSHPQHELAKRQCSGCPGMVS 314 Query: 291 FEVDGDFDSTRRFIDSVKIPYHAPSFGGCESIIDQPAIMSYWDSKEQ-RDIYGIKDNLIR 115 F + G + F+ ++K+ A S GG ES+ + PAIM++ E+ R GI D LIR Sbjct: 315 FYIKGALQHAKAFLKNLKLFTLAESLGGYESLAELPAIMTHASVPEKDRATLGINDTLIR 374 Query: 114 FSIGVEDFGDLKNDIVQAL 58 S+G+ED DL D+ +AL Sbjct: 375 LSVGLEDEQDLLEDLDRAL 393
>METB_MYCTU (P66875) Cystathionine gamma-synthase (EC 2.5.1.48) (CGS)| (O-succinylhomoserine (thiol)-lyase) Length = 388 Score = 156 bits (394), Expect = 6e-38 Identities = 82/198 (41%), Positives = 120/198 (60%), Gaps = 1/198 (0%) Frame = -2 Query: 648 QKALTLGADIVVHSATKYIAGHNDVIGGC-ISGRGELVSKVRIYHHVVGGVLNPNASYLI 472 Q+ L LGAD+V+HS TKYI GH+DV+GG ++ EL + + G V P +YL Sbjct: 192 QQPLRLGADVVLHSTTKYIGGHSDVVGGALVTNDEELDEEFAFLQNGAGAVPGPFDAYLT 251 Query: 471 LRGMKTLHLRVQCQNNTALRMAQFLEEHPKIARVYYPGLPSHPEHHIAKSQMTGFGGVVS 292 +RG+KTL LR+Q + A +A+FL +HP ++ V YPGLPSHP H IA QM GFGG+VS Sbjct: 252 MRGLKTLVLRMQRHSENACAVAEFLADHPSVSSVLYPGLPSHPGHEIAARQMRGFGGMVS 311 Query: 291 FEVDGDFDSTRRFIDSVKIPYHAPSFGGCESIIDQPAIMSYWDSKEQRDIYGIKDNLIRF 112 + + + ++ A S GG ES+I+ P+ M++ + + + D+L+R Sbjct: 312 VRMRAGRRAAQDLCAKTRVFILAESLGGVESLIEHPSAMTHASTAGSQ--LEVPDDLVRL 369 Query: 111 SIGVEDFGDLKNDIVQAL 58 S+G+ED DL D+ QAL Sbjct: 370 SVGIEDIADLLGDLEQAL 387
>METB_MYCBO (P66876) Cystathionine gamma-synthase (EC 2.5.1.48) (CGS)| (O-succinylhomoserine (thiol)-lyase) Length = 388 Score = 156 bits (394), Expect = 6e-38 Identities = 82/198 (41%), Positives = 120/198 (60%), Gaps = 1/198 (0%) Frame = -2 Query: 648 QKALTLGADIVVHSATKYIAGHNDVIGGC-ISGRGELVSKVRIYHHVVGGVLNPNASYLI 472 Q+ L LGAD+V+HS TKYI GH+DV+GG ++ EL + + G V P +YL Sbjct: 192 QQPLRLGADVVLHSTTKYIGGHSDVVGGALVTNDEELDEEFAFLQNGAGAVPGPFDAYLT 251 Query: 471 LRGMKTLHLRVQCQNNTALRMAQFLEEHPKIARVYYPGLPSHPEHHIAKSQMTGFGGVVS 292 +RG+KTL LR+Q + A +A+FL +HP ++ V YPGLPSHP H IA QM GFGG+VS Sbjct: 252 MRGLKTLVLRMQRHSENACAVAEFLADHPSVSSVLYPGLPSHPGHEIAARQMRGFGGMVS 311 Query: 291 FEVDGDFDSTRRFIDSVKIPYHAPSFGGCESIIDQPAIMSYWDSKEQRDIYGIKDNLIRF 112 + + + ++ A S GG ES+I+ P+ M++ + + + D+L+R Sbjct: 312 VRMRAGRRAAQDLCAKTRVFILAESLGGVESLIEHPSAMTHASTAGSQ--LEVPDDLVRL 369 Query: 111 SIGVEDFGDLKNDIVQAL 58 S+G+ED DL D+ QAL Sbjct: 370 SVGIEDIADLLGDLEQAL 387
>METC_ARATH (P53780) Cystathionine beta-lyase, chloroplast precursor (EC| 4.4.1.8) (CBL) (Beta-cystathionase) (Cysteine lyase) Length = 464 Score = 149 bits (375), Expect = 9e-36 Identities = 80/194 (41%), Positives = 120/194 (61%), Gaps = 2/194 (1%) Frame = -2 Query: 645 KALTLGADIVVHSATKYIAGHNDVIGGCISGRGELVSK-VRIYHHVVGGVLNPNASYLIL 469 + L LGADIV+HSATK+IAGH+DV+ G ++ +GE ++K V + G L P +L L Sbjct: 263 RPLELGADIVMHSATKFIAGHSDVMAGVLAVKGEKLAKEVYFLQNSEGSGLAPFDCWLCL 322 Query: 468 RGMKTLHLRVQCQNNTALRMAQFLEEHPKIARVYYPGLPSHPEHHIAKSQMTGFGGVVSF 289 RG+KT+ LR++ Q A ++A +L HP++ +VYY GLP HP HH+ SQ G G V SF Sbjct: 323 RGIKTMALRIEKQQENARKIAMYLSSHPRVKKVYYAGLPDHPGHHLHFSQAKGAGSVFSF 382 Query: 288 EVDGDFDSTRRFIDSVKIPYHAPSFGGCESIIDQPAIMSYWD-SKEQRDIYGIKDNLIRF 112 + G ++ +++ K A SFG +S+I P MS+ E R+ G+ ++L+R Sbjct: 383 -ITGSVALSKHLVETTKYFSIAVSFGSVKSLISMPCFMSHASIPAEVREARGLTEDLVRI 441 Query: 111 SIGVEDFGDLKNDI 70 S G+ED DL +D+ Sbjct: 442 SAGIEDVDDLISDL 455
>CYS3_YEAST (P31373) Cystathionine gamma-lyase (EC 4.4.1.1)| (Gamma-cystathionase) Length = 393 Score = 140 bits (354), Expect = 3e-33 Identities = 78/199 (39%), Positives = 123/199 (61%), Gaps = 5/199 (2%) Frame = -2 Query: 639 LTLGADIVVHSATKYIAGHNDVIGGCISGRGE-LVSKVRIYHHVVGGVLNPNASYLILRG 463 L GADIVVHSATKYI GH+DV+ G ++ + L +++ + +G + +P ++L RG Sbjct: 190 LNFGADIVVHSATKYINGHSDVVLGVLATNNKPLYERLQFLQNAIGAIPSPFDAWLTHRG 249 Query: 462 MKTLHLRVQCQNNTALRMAQFL-EEHPKIARVYYPGLPSHPEHHIAKSQMTGF--GGVVS 292 +KTLHLRV+ +A ++A+FL + + V YPGL +HP + + Q GG++S Sbjct: 250 LKTLHLRVRQAALSANKIAEFLAADKENVVAVNYPGLKTHPNYDVVLKQHRDALGGGMIS 309 Query: 291 FEVDGDFDSTRRFIDSVKIPYHAPSFGGCESIIDQPAIMSYWD-SKEQRDIYGIKDNLIR 115 F + G ++ +F S ++ A S GG ES+++ PA+M++ KE R+ G+ D+L+R Sbjct: 310 FRIKGGAEAASKFASSTRLFTLAESLGGIESLLEVPAVMTHGGIPKEAREASGVFDDLVR 369 Query: 114 FSIGVEDFGDLKNDIVQAL 58 S+G+ED DL DI QAL Sbjct: 370 ISVGIEDTDDLLEDIKQAL 388
>METB_HERAU (P24601) Probable cystathionine gamma-synthase (EC 2.5.1.48) (CGS)| (O-succinylhomoserine (thiol)-lyase) (Fragment) Length = 319 Score = 139 bits (351), Expect = 6e-33 Identities = 64/140 (45%), Positives = 94/140 (67%), Gaps = 1/140 (0%) Frame = -2 Query: 651 NQKALTLGADIVVHSATKYIAGHNDVIGGCI-SGRGELVSKVRIYHHVVGGVLNPNASYL 475 NQ+ +TLGAD+V+HS TKYI GH+DV+GG I + EL K++ + G V P +L Sbjct: 180 NQRPITLGADMVLHSTTKYIGGHSDVVGGAIMTSNDELYEKLKFLQNAAGAVPGPFDCWL 239 Query: 474 ILRGMKTLHLRVQCQNNTALRMAQFLEEHPKIARVYYPGLPSHPEHHIAKSQMTGFGGVV 295 +LRG+KTL +R++ AL +AQFL EHP + +V YPGLPSHP+H++A+ QM GFGG++ Sbjct: 240 VLRGVKTLSIRMRDDERNALAIAQFLTEHPGVEKVIYPGLPSHPQHNLAREQMRGFGGMI 299 Query: 294 SFEVDGDFDSTRRFIDSVKI 235 S + G ++ + K+ Sbjct: 300 SILLKGGAEAANAMVSKTKL 319
>METB_ECOLI (P00935) Cystathionine gamma-synthase (EC 2.5.1.48) (CGS)| (O-succinylhomoserine (thiol)-lyase) Length = 386 Score = 136 bits (343), Expect = 5e-32 Identities = 73/195 (37%), Positives = 117/195 (60%), Gaps = 2/195 (1%) Frame = -2 Query: 648 QKALTLGADIVVHSATKYIAGHNDVIGGCISGRG-ELVSKVRIYHHVVGGVLNPNASYLI 472 Q L LGAD+V+HS TKY+ GH+DV+ G + + ++V+++ + + +G SYL+ Sbjct: 182 QNPLALGADLVLHSCTKYLNGHSDVVAGVVIAKDPDVVTELAWWANNIGVTGGAFDSYLL 241 Query: 471 LRGMKTLHLRVQCQNNTALRMAQFLEEHPKIARVYYPGLPSHPEHHIAKSQMTGFGGVVS 292 LRG++TL R++ A + ++L+ P + ++Y+P LP + H IA Q GFG ++S Sbjct: 242 LRGLRTLVPRMELAQRNAQAIVKYLQTQPLVKKLYHPSLPENQGHEIAARQQKGFGAMLS 301 Query: 291 FEVDGDFDSTRRFIDSVKIPYHAPSFGGCESIIDQPAIMSYWD-SKEQRDIYGIKDNLIR 115 FE+DGD + RRF+ + + A S GG ES+I A M++ + E R GI + L+R Sbjct: 302 FELDGDEQTLRRFLGGLSLFTLAESLGGVESLISHAATMTHAGMAPEARAAAGISETLLR 361 Query: 114 FSIGVEDFGDLKNDI 70 S G+ED DL D+ Sbjct: 362 ISTGIEDGEDLIADL 376
>METB_HAEIN (P44502) Cystathionine gamma-synthase (EC 2.5.1.48) (CGS)| (O-succinylhomoserine (thiol)-lyase) Length = 369 Score = 131 bits (330), Expect = 2e-30 Identities = 78/197 (39%), Positives = 112/197 (56%), Gaps = 2/197 (1%) Frame = -2 Query: 645 KALTLGADIVVHSATKYIAGHNDVIGGCISGRG-ELVSKVRIYHHVVGGVLNPNASYLIL 469 + L LGAD+V+HS TKYIAGHND + G I +G EL ++ + G VL+P S+L + Sbjct: 185 RPLDLGADVVIHSGTKYIAGHNDALVGLIVAKGQELCDRIAYIQNGAGAVLSPFDSWLTI 244 Query: 468 RGMKTLHLRVQCQNNTALRMAQFLEEHPKIARVYYPGLPSHPEHHIAKSQMTGFGGVVSF 289 RGMKTL LR++ A +A+FL+ P++ V YP GG++SF Sbjct: 245 RGMKTLSLRMKRHQENAQAIAEFLKAQPQVESVLYPNK----------------GGMLSF 288 Query: 288 EVDGDFDSTRRFIDSVKIPYHAPSFGGCESIIDQPAIMSYWDSKE-QRDIYGIKDNLIRF 112 + D F+ S+K+ A S GG ES I PA ++ D E +R GI + L+RF Sbjct: 289 RLQ-DEAWVNTFLKSIKLITFAESLGGTESFITYPATQTHMDIPESERVARGITNTLLRF 347 Query: 111 SIGVEDFGDLKNDIVQA 61 S+G+ED D+K D++QA Sbjct: 348 SVGIEDVEDIKADLLQA 364
>CYSA_STRCO (Q59829) Putative cystathionine gamma-lyase (EC 4.4.1.1)| (Gamma-cystathionase) Length = 392 Score = 125 bits (314), Expect = 1e-28 Identities = 76/205 (37%), Positives = 116/205 (56%), Gaps = 4/205 (1%) Frame = -2 Query: 654 INQKALTLGADIVVHSATKYIAGHNDVIGGCISGRGE-LVSKVRIYHHVVGGVLNPNASY 478 + Q+ L LGAD V S TK + GH DV+ G ++GR ++ VR + +VG + P ++ Sbjct: 198 LGQRPLELGADFSVASGTKQLTGHGDVLLGYVAGRDAGAMAAVRRWRKIVGAIPGPMEAW 257 Query: 477 LILRGMKTLHLRVQCQNNTALRMAQFLEEHPKIARVYYPGLPSHPEHHIAKSQMTGFGGV 298 L R + TL LRV Q++TAL++A+ L P+I + YPGLP P H +A QM +G V Sbjct: 258 LAHRSIATLQLRVDRQDSTALKVAEALRTRPEITGLRYPGLPDDPSHKVASQQMLRYGCV 317 Query: 297 VSFEVDGDFDSTRRFIDSVKIPYHAPSFGGCESIIDQPAIMSYWDSKEQRDIYG---IKD 127 VSF + + RF+D++++ A SFGG S + E+R +G + + Sbjct: 318 VSFTLPSRARAD-RFLDALRLVEGATSFGGVRS------------TAERRGRWGGDAVPE 364 Query: 126 NLIRFSIGVEDFGDLKNDIVQALDK 52 IR S+G ED DL D+++ALD+ Sbjct: 365 GFIRLSVGAEDPDDLVADLLRALDE 389
>CYSD_SCHPO (O13326) O-acetylhomoserine (thiol)-lyase (EC 2.5.1.49)| (O-acetylhomoserine sulfhydrylase) (OAH sulfhydrylase) (Homocysteine synthase) Length = 429 Score = 120 bits (302), Expect = 3e-27 Identities = 74/228 (32%), Positives = 116/228 (50%), Gaps = 36/228 (15%) Frame = -2 Query: 630 GADIVVHSATKYIAGHNDVIGGCISGRGELVSKVRI------------YHHVV------- 508 GADIV HSATK+I GH IGG I G+ K YH +V Sbjct: 200 GADIVTHSATKWIGGHGTTIGGVIVDSGKFDWKKNSKRFPEFNEPHPGYHGMVFTETFGN 259 Query: 507 ---------------GGVLNPNASYLILRGMKTLHLRVQCQNNTALRMAQFLEEHPKIAR 373 GG NP +L+L+G++TL LR++ A +A++LE+HPK+ Sbjct: 260 LAYAFACRTQTLRDVGGNANPFGVFLLLQGLETLSLRMERHVQNAFALAKYLEKHPKVNW 319 Query: 372 VYYPGLPSHPEHHIAKSQM-TGFGGVVSFEVDGDFDSTRRFIDSVKIPYHAPSFGGCESI 196 V YPGL SH H +AK + G+G V+SF G D +R+ ++++K+ + G +++ Sbjct: 320 VSYPGLESHVSHKLAKKYLKNGYGAVLSFGAKGGPDQSRKVVNALKLASQLANVGDAKTL 379 Query: 195 IDQPAIMSYWDSKEQRDI-YGIKDNLIRFSIGVEDFGDLKNDIVQALD 55 + PA ++ ++ I G+ +LIR ++G+E D+ D QAL+ Sbjct: 380 VIAPAYTTHLQLTDEEQISAGVTKDLIRVAVGIEHIDDIIADFAQALE 427
>MET17_YEAST (P06106) Protein MET17 [Includes: O-acetylhomoserine sulfhydrylase| (EC 2.5.1.49) (OAH sulfhydrylase) (Homocysteine synthase); O-acetylserine sulfhydrylase (EC 2.5.1.47) (OAS sulfhydrylase)] Length = 443 Score = 109 bits (273), Expect = 6e-24 Identities = 76/240 (31%), Positives = 122/240 (50%), Gaps = 46/240 (19%) Frame = -2 Query: 630 GADIVVHSATKYIAGHNDVIGGCISGRGELVSK------------VRIYH---------- 517 GADIV HSATK+I GH IGG I G+ K YH Sbjct: 198 GADIVTHSATKWIGGHGTTIGGIIVDSGKFPWKDYPEKFPQFSQPAEGYHGTIYNEAYGN 257 Query: 516 -----HV-------VGGVLNPNASYLILRGMKTLHLRVQCQNNTALRMAQFLEEHPKIAR 373 HV +G ++NP AS+L+L+G++TL LR + AL++A++LE+ P ++ Sbjct: 258 LAYIVHVRTELLRDLGPLMNPFASFLLLQGVETLSLRAERHGENALKLAKWLEQSPYVSW 317 Query: 372 VYYPGLPSHPEHHIAKSQMT-GFGGVVSFEV------DGDFD----STRRFIDSVKIPYH 226 V YPGL SH H AK ++ GFGGV+SF V D + D S + +D++K+ + Sbjct: 318 VSYPGLASHSHHENAKKYLSNGFGGVLSFGVKDLPNADKETDPFKLSGAQVVDNLKLASN 377 Query: 225 APSFGGCESIIDQPAIMSYWDSKEQRDI-YGIKDNLIRFSIGVEDFGDLKNDIVQALDKI 49 + G ++++ P ++ ++ + G+ +LIR S+G+E D+ D Q+ + + Sbjct: 378 LANVGDAKTLVIAPYFTTHKQLNDKEKLASGVTKDLIRVSVGIEFIDDIIADFQQSFETV 437
>STR3_YEAST (P53101) Cystathionine beta-lyase (EC 4.4.1.8) (CBL)| (Beta-cystathionase) (Cysteine lyase) Length = 465 Score = 108 bits (271), Expect = 1e-23 Identities = 73/210 (34%), Positives = 113/210 (53%), Gaps = 12/210 (5%) Frame = -2 Query: 651 NQKALTLGADIVVHSATKYIAGHNDVIGGCI-SGRGELVSKVRIYHHVVGGVLNPNASYL 475 N L G D+V SATKY+ GH+D++GG I S E+ SK+ + G L+P S+L Sbjct: 196 NPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINSTGAGLSPMDSWL 255 Query: 474 ILRGMKTLHLRVQCQNNTALRMAQFLEEH--------PKIARVYYPGLPSHPEHHIAKSQ 319 ++RG+KTL +R+ Q A+ +A +LE K + + GL S+P+ + KS Sbjct: 256 LVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGLRSNPDFKLHKSF 315 Query: 318 MTGFGGVVSFEVDGDFDSTRRFIDSVKIPYHA--PSFGGCESIIDQPAIMSYWD-SKEQR 148 G G V+SFE G F+ ++R + S K+ A SFG S++ P MS+ E R Sbjct: 316 NNGPGAVLSFET-GSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCKMSHASIDPELR 374 Query: 147 DIYGIKDNLIRFSIGVEDFGDLKNDIVQAL 58 ++L+R G+E+ DLK D++ A+ Sbjct: 375 KERDFPEDLVRLCCGIENIVDLKKDLLAAM 404
>MET17_KLULA (Q92441) Protein MET17 [Includes: O-acetylhomoserine sulfhydrylase| (EC 2.5.1.49) (OAH sulfhydrylase) (Homocysteine synthase); O-acetylserine sulfhydrylase (EC 2.5.1.47) (OAS sulfhydrylase)] Length = 443 Score = 105 bits (263), Expect = 9e-23 Identities = 74/232 (31%), Positives = 114/232 (49%), Gaps = 46/232 (19%) Frame = -2 Query: 630 GADIVVHSATKYIAGHNDVIGGCISGRGELVSK------------VRIYHHVV------- 508 GADIV HSATK+I GH +GG I G+ K YH ++ Sbjct: 197 GADIVTHSATKWIGGHGVTVGGVIIDSGKFPWKDYPEKFPQFSQPSEGYHGLIFNDAFGP 256 Query: 507 ---------------GGVLNPNASYLILRGMKTLHLRVQCQNNTALRMAQFLEEHPKIAR 373 G VL+P A +L+L+G++TL LR + + AL++AQ+LE P ++ Sbjct: 257 AAFIGHVRTELLRDLGPVLSPFAGFLLLQGLETLSLRGERHGSNALKLAQYLESSPYVSW 316 Query: 372 VYYPGLPSHPEHHIAKSQM-TGFGGVVSF----------EVDGDFDSTRRFIDSVKIPYH 226 V YPGLPSH H AK + GFGGV+SF E D S + +D++K+ + Sbjct: 317 VSYPGLPSHSHHENAKKYLENGFGGVLSFGVKDLPNASEESDPFKASGAQVVDNLKLASN 376 Query: 225 APSFGGCESIIDQPAIMSYWD-SKEQRDIYGIKDNLIRFSIGVEDFGDLKND 73 + G ++++ P ++ + E++ G+ +LIR S+G E D+ D Sbjct: 377 LANVGDSKTLVIAPYFTTHQQLTDEEKLASGVTKDLIRVSVGTEFIDDIIAD 428
>METC_ECOLI (P06721) Cystathionine beta-lyase (EC 4.4.1.8) (CBL)| (Beta-cystathionase) (Cysteine lyase) Length = 395 Score = 105 bits (262), Expect = 1e-22 Identities = 62/196 (31%), Positives = 111/196 (56%), Gaps = 4/196 (2%) Frame = -2 Query: 645 KALTLGADIVVHSATKYIAGHNDVIGGCISGRGELVSKVRIYHHVVGGVLNPNASYLILR 466 KAL G D+ + +ATKY+ GH+D + G ++R +++G +++ + +Y+ R Sbjct: 195 KALDFGIDVSIQAATKYLVGHSDAMIGTAVCNARCWEQLRENAYLMGQMVDADTAYITSR 254 Query: 465 GMKTLHLRVQCQNNTALRMAQFLEEHPKIARVYYPGLPSHPEHHIAKSQMTGFGGVVSFE 286 G++TL +R++ + ++L++A++L EHP++ARV +P LP H K TG G+ SF Sbjct: 255 GLRTLGVRLRQHHESSLKVAEWLAEHPQVARVNHPALPGSKGHEFWKRDFTGSSGLFSFV 314 Query: 285 VDGDFDSTR--RFIDSVKIPYHAPSFGGCESII--DQPAIMSYWDSKEQRDIYGIKDNLI 118 + ++ ++D+ + A S+GG ES+I +QP ++ + + D G LI Sbjct: 315 LKKKLNNEELANYLDNFSLFSMAYSWGGYESLILANQPEHIAAIRPQGEIDFSG---TLI 371 Query: 117 RFSIGVEDFGDLKNDI 70 R IG+ED DL D+ Sbjct: 372 RLHIGLEDVDDLIADL 387
>METC_HAEIN (P44527) Cystathionine beta-lyase (EC 4.4.1.8) (CBL)| (Beta-cystathionase) (Cysteine lyase) Length = 396 Score = 103 bits (256), Expect = 6e-22 Identities = 60/203 (29%), Positives = 116/203 (57%), Gaps = 4/203 (1%) Frame = -2 Query: 645 KALTLGADIVVHSATKYIAGHNDVIGGCISGRGELVSKVRIYHHVVGGVLNPNASYLILR 466 KAL DI + + TKY+ GH+D++ G ++R + +++G +++ +++Y R Sbjct: 196 KALEHDIDISIQAGTKYLVGHSDIMIGTAVANARTWDQLREHSYLMGQMVDADSAYTTAR 255 Query: 465 GMKTLHLRVQCQNNTALRMAQFLEEHPKIARVYYPGLPSHPEHHIAKSQMTGFGGVVSFE 286 G++TL +R++ +++++A++L E P++ VY+P LPS P H +G G+ SFE Sbjct: 256 GIRTLGVRLKQHQESSIKVAKWLSEQPEVKTVYHPALPSCPGHEFFLRDFSGSSGLFSFE 315 Query: 285 VDGDFDSTR--RFIDSVKIPYHAPSFGGCESII--DQPAIMSYWDSKEQRDIYGIKDNLI 118 + S + +F+D ++ A S+GG ES+I +QP +++ +R++ G +LI Sbjct: 316 LTQRLTSEQVSKFMDHFQLFAMAYSWGGFESLILCNQPEEIAHIRPNIKRNLTG---SLI 372 Query: 117 RFSIGVEDFGDLKNDIVQALDKI 49 R IG E+ +L D+ ++I Sbjct: 373 RVHIGFENVDELIADLKAGFERI 395
>METC_BORAV (Q07703) Cystathionine beta-lyase (EC 4.4.1.8) (CBL)| (Beta-cystathionase) (Cysteine lyase) (Osteotoxin) Length = 395 Score = 101 bits (252), Expect = 2e-21 Identities = 59/204 (28%), Positives = 112/204 (54%), Gaps = 6/204 (2%) Frame = -2 Query: 645 KALTLGADIVVHSATKYIAGHNDVIGGCISGRGELVSK-VRIYHHVVGGVLNPNASYLIL 469 + LTLGA + V + TKY+ GH+D++ G + E ++K + + +G ++ + ++L L Sbjct: 198 RPLTLGAQVSVIAGTKYVGGHSDLMLGAVVTNDEAIAKRLNRTQYALGYSVSADDAWLAL 257 Query: 468 RGMKTLHLRVQCQNNTALRMAQFLEEHPKIARVYYPGLPSHPEHHIAKSQMTGFGGVVSF 289 RG++T+ +R+ AL + +FL+ P++ R+Y+P P+ P H + + +G G+++ Sbjct: 258 RGVRTMPVRMAQHARHALEVCEFLQNRPEVVRLYHPAWPADPGHALWQRDCSGSNGMLAV 317 Query: 288 EVDGDFDSTRRFIDSVKIPYHAPSFGGCESIID-----QPAIMSYWDSKEQRDIYGIKDN 124 ++ + R F++++ + S+GG ES++ + A YW G D Sbjct: 318 QLGLSPQAARDFVNALTLFGIGFSWGGFESLVQLVTPGELARHQYWQ--------GGSDA 369 Query: 123 LIRFSIGVEDFGDLKNDIVQALDK 52 L+R IG+E DL D+ QALD+ Sbjct: 370 LVRLHIGLESPADLIADLAQALDR 393
>CYSD_EMENI (P50125) O-acetylhomoserine (thiol)-lyase (EC 2.5.1.49)| (O-acetylhomoserine sulfhydrylase) (OAH sulfhydrylase) (Homocysteine synthase) Length = 437 Score = 100 bits (249), Expect = 4e-21 Identities = 68/226 (30%), Positives = 112/226 (49%), Gaps = 36/226 (15%) Frame = -2 Query: 630 GADIVVHSATKYIAGHNDVIGGCI--SGR-----------------------------GE 544 GADIVVHSATK+I GH IGG + SG+ G Sbjct: 201 GADIVVHSATKWIGGHGTTIGGVVVDSGKFEWGKNAARFPQFTQPSEGYHGLNFWETFGP 260 Query: 543 LVSKVRIYHHVV---GGVLNPNASYLILRGMKTLHLRVQCQNNTALRMAQFLEEHPKIAR 373 + +R+ ++ G LNP A+ ++ G++TL LR + + AL +A +L+++ ++ Sbjct: 261 IAFAIRVRVEILRDLGSALNPFAAQQLILGLETLSLRAERHASNALALANWLKKNDHVSW 320 Query: 372 VYYPGLPSHPEHHIAKSQM-TGFGGVVSFEVDGDFDSTRRFIDSVKIPYHAPSFGGCESI 196 V Y GL HP H +AK + GFGGV+SF V G+ + +D+ K+ + + G +++ Sbjct: 321 VSYVGLEEHPSHGVAKKYLKRGFGGVLSFGVKGEAAVGSQVVDNFKLISNLANVGDSKTL 380 Query: 195 IDQPAIMSYWDSKEQRDI-YGIKDNLIRFSIGVEDFGDLKNDIVQA 61 P ++ +Q I G+ ++ IR S+G E D+ D Q+ Sbjct: 381 AIHPWSTTHEQLTDQERIDSGVTEDAIRISVGTEHIDDIIADFEQS 426
>METC_SALTY (P18949) Cystathionine beta-lyase (EC 4.4.1.8) (CBL)| (Beta-cystathionase) (Cysteine lyase) Length = 395 Score = 95.1 bits (235), Expect = 2e-19 Identities = 60/203 (29%), Positives = 104/203 (51%), Gaps = 4/203 (1%) Frame = -2 Query: 645 KALTLGADIVVHSATKYIAGHNDVIGGCISGRGELVSKVRIYHHVVGGVLNPNASYLILR 466 KAL DI + + TKY+ GH+D + G ++R +++G +L+ + +Y+ R Sbjct: 195 KALEFDIDISIQAGTKYLIGHSDAMVGTAVANARCWEQLRENAYLMGQMLDADTAYMTSR 254 Query: 465 GMKTLHLRVQCQNNTALRMAQFLEEHPKIARVYYPGLPSHPEHHIAKSQMTGFGGVVSFE 286 G++TL +R++ ++L++A +L HP++ARV +P LP H K TG G+ SF Sbjct: 255 GLRTLGVRLRQHQESSLKIAAWLANHPQVARVNHPALPGSKGHAFWKRDFTGSSGLFSFV 314 Query: 285 VDGDFDSTR--RFIDSVKIPYHAPSFGGCESII--DQPAIMSYWDSKEQRDIYGIKDNLI 118 ++ ++D+ + A S+GG ES+I +QP ++ D G L+ Sbjct: 315 LNKKLTEAELSAYLDNFSLFSMAYSWGGYESLIIANQPEQIAAIRPAGGVDFTG---TLV 371 Query: 117 RFSIGVEDFGDLKNDIVQALDKI 49 R IG+E DL D+ +I Sbjct: 372 RVHIGLESVDDLIADLAAGFARI 394
>YHR2_YEAST (P38716) Hypothetical 42.4 kDa protein in CDC12-ORC6 intergenic| region Length = 378 Score = 84.7 bits (208), Expect = 2e-16 Identities = 60/209 (28%), Positives = 105/209 (50%), Gaps = 9/209 (4%) Frame = -2 Query: 648 QKALTLGADIVVHSATKYIAGHNDVIGGCISGRGELVSKV----RIYHHVVGGVLNPNAS 481 Q A GADIV++SATKY GH+D++ G + + E S+ RIY +G + S Sbjct: 182 QYAWNFGADIVLYSATKYFGGHSDLLSGVLVVKEEATSRQLKDDRIY---LGTNVANLES 238 Query: 480 YLILRGMKTLHLRVQCQNNTALRMAQFLEEHPK-----IARVYYPGLPSHPEHHIAKSQM 316 +++LR ++T +R+ Q+ A ++ +FL +H + +Y+ L + E + K + Sbjct: 239 FMLLRSLRTYEMRITKQSENATKLVRFLSDHQSEFDKVLKTIYHSSLQT--EEFVKKQLV 296 Query: 315 TGFGGVVSFEVDGDFDSTRRFIDSVKIPYHAPSFGGCESIIDQPAIMSYWDSKEQRDIYG 136 G+G V + + + ++ +K +HA S GG ES+++ A+ + Sbjct: 297 GGYGPVFAITLYTK-EQCKQLPLKLKYFHHATSLGGIESLVEWRAMTDPY---------- 345 Query: 135 IKDNLIRFSIGVEDFGDLKNDIVQALDKI 49 I LIR S+G E DL D+ AL ++ Sbjct: 346 IDQTLIRVSVGCESANDLIKDLASALKEL 374
>YFHE_SCHPO (O42851) Hypothetical protein C23A1.14c in chromosome I| Length = 398 Score = 84.3 bits (207), Expect = 3e-16 Identities = 64/208 (30%), Positives = 99/208 (47%), Gaps = 15/208 (7%) Frame = -2 Query: 648 QKALTLGADIVVHSATKYIAGHNDVIGGCISGRG-ELVSKVRIYHHVVGGVLNPNASYLI 472 Q AL LGAD VVHSATKY+AGH+DV+ G + + + ++ +G +L+P ++L+ Sbjct: 196 QDALVLGADYVVHSATKYLAGHSDVLAGVTASKDRSKILDLKADRAYLGTILHPQQAFLL 255 Query: 471 LRGMKTLHLRVQCQNNTALRMAQFLE--------------EHPKIARVYYPGLPSHPEHH 334 LR ++T LR+ + +AQ L + I VY+ L + + Sbjct: 256 LRSLRTFPLRIAKHSENGFLVAQHLNKLATDEQFATSLGIDSSLILEVYHNSLQT--KEF 313 Query: 333 IAKSQMTGFGGVVSFEVDGDFDSTRRFIDSVKIPYHAPSFGGCESIIDQPAIMSYWDSKE 154 +AK+ G S + D + +K +HA S G ES+I+ + DSK Sbjct: 314 VAKNLTGGHASCFSVLLKSD-TVAKHLCCELKYFHHATSLGSVESLIEWRRMT---DSK- 368 Query: 153 QRDIYGIKDNLIRFSIGVEDFGDLKNDI 70 I L+R SIG+ED DL D+ Sbjct: 369 ------IDPRLVRLSIGIEDAADLIADL 390
>MET7_SCHPO (O74314) Probable cystathionine gamma-synthase (EC 2.5.1.48)| (O-succinylhomoserine (thiol)-lyase) Length = 610 Score = 72.4 bits (176), Expect = 1e-12 Identities = 57/203 (28%), Positives = 101/203 (49%), Gaps = 4/203 (1%) Frame = -2 Query: 654 INQKALTLGADIVVHSATKYIAGHNDVIGGC--ISGRGELVSKVR-IYHHVVGGVLNPNA 484 +N + L L AD+VV S TK +G ++V+GG ++ S+++ + +L Sbjct: 410 VNVEVLPL-ADVVVSSLTKIFSGDSNVMGGSMVLNPSSRYYSRIKDAMKALYEDLLYDED 468 Query: 483 SYLILRGMKTLHLRVQCQNNTALRMAQFLEEHPKIARVYYPGLPSHPEHHIA-KSQMTGF 307 + + R + R Q N+ A + L ++PKI +YYP + EH A + + G+ Sbjct: 469 ALTLERNSRDFAERSQVINHNAETICNLLYQNPKIKTLYYPKYNTSKEHFEACRRENGGY 528 Query: 306 GGVVSFEVDGDFDSTRRFIDSVKIPYHAPSFGGCESIIDQPAIMSYWDSKEQRDIYGIKD 127 GG++S D+ R+F D +++ PS G ++ AI++++ + GI Sbjct: 529 GGLLSVVFHNPEDA-RQFYDKIQVA-KGPSLGTNFTLASPYAILAHYQELDWAGENGIDR 586 Query: 126 NLIRFSIGVEDFGDLKNDIVQAL 58 NL+R S+G+E LKN + AL Sbjct: 587 NLVRVSVGMEPSEHLKNVFINAL 609
>MET7_NEUCR (P38675) Cystathionine gamma-synthase (EC 2.5.1.48)| (O-succinylhomoserine (thiol)-lyase) Length = 542 Score = 65.1 bits (157), Expect = 2e-10 Identities = 50/199 (25%), Positives = 90/199 (45%), Gaps = 9/199 (4%) Frame = -2 Query: 627 ADIVVHSATKYIAGHNDVIGGCISGRGELVSKVRIYHHVVGGVLN--------PNASYLI 472 ADIVV S TK +G +V+GG G + + Y+ + + P + Sbjct: 341 ADIVVSSLTKIFSGDCNVMGG-----GAIFNPNSRYYSALKSFVQQQLEDTYWPEDVIFM 395 Query: 471 LRGMKTLHLRVQCQNNTALRMAQFLEEHPKIARVYYPGL-PSHPEHHIAKSQMTGFGGVV 295 R + R+ N A + + L++HP + +YYP S + K G+GG++ Sbjct: 396 ERNSRDFVARIDRVNANAEAICRVLQDHPLVKTLYYPKYNDSRANYEAVKLPQGGYGGLI 455 Query: 294 SFEVDGDFDSTRRFIDSVKIPYHAPSFGGCESIIDQPAIMSYWDSKEQRDIYGIKDNLIR 115 S + G + F D+++ PS G ++ +++++ + + YG+ NLIR Sbjct: 456 SVVLKGKKQAVA-FYDAIETA-KGPSLGTNFTLTSPYVLLAHYQELDWAEQYGVDRNLIR 513 Query: 114 FSIGVEDFGDLKNDIVQAL 58 S+G+E +L N +AL Sbjct: 514 ISVGLEGTDELINVFTRAL 532
>METC_YEAST (P43623) Putative cystathionine beta-lyase (EC 4.4.1.8) (CBL)| (Beta-cystathionase) (Cysteine lyase) Length = 340 Score = 64.3 bits (155), Expect = 3e-10 Identities = 40/143 (27%), Positives = 66/143 (46%), Gaps = 2/143 (1%) Frame = -2 Query: 630 GADIVVHSATKYIAGHNDVIGGCISGRGELVSKVRIYHHVVGGVLNPNASYLILRGMKTL 451 G DI V + TKY+ GH+D++ G S E +R + + + L LRGM+TL Sbjct: 198 GIDISVEAGTKYLGGHSDLLIGLASANEECWPLLRSTYDAMAMLPGAEDCQLALRGMRTL 257 Query: 450 HLRVQCQNNTALRMAQFLEEHPKIARVYYPGLPSHPEHHIAKSQMTGFGGVVSFEVDGDF 271 HLR++ AL +A +L ++ +V +P P H G G+ S + F Sbjct: 258 HLRLKEVERKALDLAAWLGNRDEVEKVLHPAFEDCPGHEYWVRDYKGSSGLFSIVLKNGF 317 Query: 270 D--STRRFIDSVKIPYHAPSFGG 208 + ++ +K+ S+GG Sbjct: 318 TRAGLEKMVEGMKVLQLGFSWGG 340
>MET7_YEAST (P47164) Cystathionine gamma-synthase (EC 2.5.1.48)| (O-succinylhomoserine (thiol)-lyase) Length = 639 Score = 54.3 bits (129), Expect = 3e-07 Identities = 49/204 (24%), Positives = 97/204 (47%), Gaps = 12/204 (5%) Frame = -2 Query: 627 ADIVVHSATKYIAGHNDVIGGCI--SGRGELVSKVRIYHHVVGGVLN----PNASYLILR 466 ADIV S TK +G ++VI G + + RG++ R + G + +A L Sbjct: 434 ADIVCSSLTKIFSGDSNVIAGSLVLNPRGKIYEFARKFMKTEDGYEDCLWCEDALCLERN 493 Query: 465 GMKTLHLRVQCQNNTALRMAQFL--EEHPKIARVYYPGLPSHPEHHIAKSQMT----GFG 304 + ++ NT + + + L + ++YYP L S S M+ G+G Sbjct: 494 SRDFVERTIKVNTNTDILLKRVLLPQVGKLFKKIYYPSLTSEDTKRNYDSVMSTKDGGYG 553 Query: 303 GVVSFEVDGDFDSTRRFIDSVKIPYHAPSFGGCESIIDQPAIMSYWDSKEQRDIYGIKDN 124 G+ S + + ++F +++++ PS G ++ AI++++ ++ YG++ N Sbjct: 554 GLFSLTFF-NIEEAKKFFNNLEL-CKGPSLGTNFTLACPYAIIAHYQELDEVAQYGVETN 611 Query: 123 LIRFSIGVEDFGDLKNDIVQALDK 52 L+R S+G+E+ L N +A++K Sbjct: 612 LVRVSVGLENSDVLCNVFQRAIEK 635
>METX_YEAST (Q04533) Putative cystathionine gamma-synthase YML082W (EC 2.5.1.48)| (O-succinylhomoserine (thiol)-lyase) Length = 649 Score = 52.8 bits (125), Expect = 9e-07 Identities = 52/206 (25%), Positives = 90/206 (43%), Gaps = 14/206 (6%) Frame = -2 Query: 627 ADIVVHSATKYIAGHNDVIGGCI-----SGRGELVSKVRIYHHVVGGVL-NPNASYLILR 466 ADIV S TK +G ++VIGG + S E S+ +L +A YL Sbjct: 442 ADIVCSSLTKTFSGDSNVIGGSMVLNPQSRVYEFASRFMQLEDEYEDLLWCEDAIYLERN 501 Query: 465 GMKTLHLRVQCQNNTALRMAQFLEEH----PKIARVYYPGLPSHPE----HHIAKSQMTG 310 + ++ +T + + L+ H ++YYP L S + + G Sbjct: 502 SRDFIARTIRINYSTEYLLDKILKPHVGENKLFKKIYYPNLTSKETLTNYDMVRCKKEGG 561 Query: 309 FGGVVSFEVDGDFDSTRRFIDSVKIPYHAPSFGGCESIIDQPAIMSYWDSKEQRDIYGIK 130 +GG+ S D D F D++K+ PS G ++ +M+Y+ + + +G++ Sbjct: 562 YGGLFSLTFH-DEDHAAAFYDNLKLN-KGPSLGTNFTLAFPYTLMTYYHELDMAEKFGVE 619 Query: 129 DNLIRFSIGVEDFGDLKNDIVQALDK 52 NL+R S+G+E L +A+DK Sbjct: 620 RNLLRISVGLESQSILGKIFQEAIDK 645
>METW_YEAST (Q12198) Putative cystathionine gamma-synthase YLL058W (EC| 2.5.1.48) (O-succinylhomoserine (thiol)-lyase) Length = 575 Score = 47.0 bits (110), Expect = 5e-05 Identities = 53/205 (25%), Positives = 92/205 (44%), Gaps = 12/205 (5%) Frame = -2 Query: 627 ADIVVHSATKYIAGHNDVIGGCI--SGRGELVSKVRIYHHVVG--GVLNPNASYLILRGM 460 ADIV S TK G ++V+GG + + + L R Y +L + ++ R Sbjct: 367 ADIVSTSLTKLFNGASNVMGGSVVLNPKSSLYPYAREYFRSANFEDLLWCEDAIVLERNS 426 Query: 459 KTLHLRVQCQN-NTALRMAQFL--EEHPKIARVYYPGLPSHP---EHHIAKSQMTGFGGV 298 + R N NT + + L EE ++YYP + S + +++ G+G + Sbjct: 427 RDFEDRTLRANANTGILLNDLLLPEEGKICKKIYYPTVTSKETFENYESVRNERGGYGCL 486 Query: 297 --VSFEVDGDFDSTRRFIDSVKIPYHAPSFGGCESIIDQPAIMSYWDSKEQRDIYGIKDN 124 V+F +GD + F DS+K+ + PS G ++ +++ E+ +G N Sbjct: 487 FSVAFFNEGD---AKAFYDSLKV-FKGPSNGTNFTLACPYVHLAHHSELEEVSKFGADPN 542 Query: 123 LIRFSIGVEDFGDLKNDIVQALDKI 49 +IR S+G+ED L ALD + Sbjct: 543 IIRVSVGLEDIQWLLKVFSSALDVV 567
>Y158_METJA (Q57622) Hypothetical protein MJ0158| Length = 374 Score = 35.8 bits (81), Expect = 0.11 Identities = 25/66 (37%), Positives = 33/66 (50%) Frame = -2 Query: 642 ALTLGADIVVHSATKYIAGHNDVIGGCISGRGELVSKVRIYHHVVGGVLNPNASYLILRG 463 AL LGAD+VV S K + G GG ++G+ ELV K+ I G P I R Sbjct: 194 ALKLGADLVVTSTDKLMEGPR---GGLLAGKKELVDKIYIEGTKFGLEAQPPLLAGIYRA 250 Query: 462 MKTLHL 445 +K +L Sbjct: 251 LKNFNL 256
>PDIA5_RAT (Q5I0H9) Protein disulfide-isomerase A5 precursor (EC 5.3.4.1)| Length = 517 Score = 31.6 bits (70), Expect = 2.2 Identities = 16/53 (30%), Positives = 25/53 (47%) Frame = -2 Query: 354 PSHPEHHIAKSQMTGFGGVVSFEVDGDFDSTRRFIDSVKIPYHAPSFGGCESI 196 P P+ + ++ GG V D DFD + SV + +HAP G C+ + Sbjct: 257 PQPPQPQVPETPWADEGGSVYHLTDEDFDQFVKEHSSVLVMFHAPWCGHCKKM 309
>PDIA5_HUMAN (Q14554) Protein disulfide-isomerase A5 precursor (EC 5.3.4.1)| (Protein disulfide isomerase-related protein) Length = 519 Score = 31.6 bits (70), Expect = 2.2 Identities = 16/53 (30%), Positives = 25/53 (47%) Frame = -2 Query: 354 PSHPEHHIAKSQMTGFGGVVSFEVDGDFDSTRRFIDSVKIPYHAPSFGGCESI 196 P P+ + ++ GG V D DFD + SV + +HAP G C+ + Sbjct: 259 PQPPQPQVPETPWADEGGSVYHLTDEDFDQFVKEHSSVLVMFHAPWCGHCKKM 311
>LRP5_MOUSE (Q91VN0) Low-density lipoprotein receptor-related protein 5| precursor (LRP7) (Lr3) Length = 1614 Score = 31.6 bits (70), Expect = 2.2 Identities = 8/20 (40%), Positives = 13/20 (65%) Frame = +1 Query: 328 GNVMFWVTWQARIVYTCNLW 387 G+ ++W WQ R ++ CN W Sbjct: 246 GDTLYWTDWQTRSIHACNKW 265
>PDIA5_MOUSE (Q921X9) Protein disulfide-isomerase A5 precursor (EC 5.3.4.1)| (Protein disulfide isomerase-related protein) Length = 517 Score = 30.8 bits (68), Expect = 3.7 Identities = 16/53 (30%), Positives = 25/53 (47%) Frame = -2 Query: 354 PSHPEHHIAKSQMTGFGGVVSFEVDGDFDSTRRFIDSVKIPYHAPSFGGCESI 196 P P+ + ++ GG V D DFD + SV + +HAP G C+ + Sbjct: 257 PLPPQPQVPETPWADEGGSVYHLTDEDFDQFVKEHSSVLVMFHAPWCGHCKKM 309
>GLYA2_VIBCH (Q9KMP4) Serine hydroxymethyltransferase 2 (EC 2.1.2.1) (Serine| methylase 2) (SHMT 2) Length = 435 Score = 30.8 bits (68), Expect = 3.7 Identities = 19/67 (28%), Positives = 28/67 (41%) Frame = -2 Query: 396 EEHPKIARVYYPGLPSHPEHHIAKSQMTGFGGVVSFEVDGDFDSTRRFIDSVKIPYHAPS 217 E H KI +PGL P H+ ++ FG + E DS ID+ K+ Sbjct: 260 EIHKKINSAVFPGLQGGPLMHVIAAKAVAFGEALGPEFRTYIDSV---IDNAKVLAEVLQ 316 Query: 216 FGGCESI 196 GC+ + Sbjct: 317 TRGCDIV 323
>UXUA_CLOPE (Q8XP15) Mannonate dehydratase (EC 4.2.1.8) (D-mannonate hydrolase)| Length = 350 Score = 29.6 bits (65), Expect = 8.2 Identities = 14/47 (29%), Positives = 24/47 (51%), Gaps = 4/47 (8%) Frame = -2 Query: 276 DFDSTRRFIDSVKIPYHAPSFG----GCESIIDQPAIMSYWDSKEQR 148 +FD+ +RFID PYH + GC + D +++Y+ + R Sbjct: 215 NFDNLKRFIDLYDSPYHGITLCTGSLGCTKVNDMVQMINYFGKERNR 261
>PYRH_CORGL (P59004) Uridylate kinase (EC 2.7.4.-) (UK) (Uridine monophosphate| kinase) (UMP kinase) Length = 243 Score = 29.6 bits (65), Expect = 8.2 Identities = 37/121 (30%), Positives = 52/121 (42%), Gaps = 4/121 (3%) Frame = -2 Query: 630 GADIVVHSATKYIAGHNDVIGGCISGRGELVSKVRI-YHHVVGGVLNPNASYLILRGMKT 454 GA+I V I G N G + RG + + R Y ++G V+N L L+ Sbjct: 50 GAEIAV-----VIGGGNFFRGAELQQRG--MDRARSDYMGMLGTVMN----CLALQDFLG 98 Query: 453 LHLRVQCQNNTALRMAQFLEEHPKIARVYYPGLPSHPEHHIAKSQMTGFG---GVVSFEV 283 H V+C+ TA+ MAQ E P LP E H+ K ++ FG G+ F Sbjct: 99 QH-GVECRVQTAINMAQVAE----------PYLPLRAERHLEKGRVVIFGAGMGMPYFST 147 Query: 282 D 280 D Sbjct: 148 D 148 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 100,540,380 Number of Sequences: 219361 Number of extensions: 2278644 Number of successful extensions: 6136 Number of sequences better than 10.0: 46 Number of HSP's better than 10.0 without gapping: 5801 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 6064 length of database: 80,573,946 effective HSP length: 108 effective length of database: 56,882,958 effective search space used: 6200242422 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
