ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
menu 
| Clone Name | rbags17j13 |
|---|---|
| Clone Library Name | barley_pub |
>DRTS_MAIZE (O81395) Bifunctional dihydrofolate reductase-thymidylate synthase| (DHFR-TS) [Includes: Dihydrofolate reductase (EC 1.5.1.3); Thymidylate synthase (EC 2.1.1.45)] Length = 521 Score = 362 bits (928), Expect = e-100 Identities = 170/188 (90%), Positives = 180/188 (95%) Frame = -1 Query: 613 REEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPT 434 REEGDLGP+YGFQWRHFGAEY+DMHADYTGKGFDQL DVI+KIKN+P+DRRIILSAWNP+ Sbjct: 334 REEGDLGPIYGFQWRHFGAEYTDMHADYTGKGFDQLMDVIDKIKNDPEDRRIILSAWNPS 393 Query: 433 DLKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSP 254 DLKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLT MIAQVCDLSP Sbjct: 394 DLKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTYMIAQVCDLSP 453 Query: 253 GEFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQ 74 G+FVHVIGDAHVY HV+ALEEQ+QK PKPFPILKINP KKDIDSF+ASDFKL YDPHQ Sbjct: 454 GDFVHVIGDAHVYRNHVRALEEQIQKMPKPFPILKINPSKKDIDSFMASDFKLVGYDPHQ 513 Query: 73 KIEMKMAV 50 KIEMKMAV Sbjct: 514 KIEMKMAV 521
>DRTS2_ARATH (Q05763) Bifunctional dihydrofolate reductase-thymidylate synthase| 2 (DHFR-TS 2) [Includes: Dihydrofolate reductase (EC 1.5.1.3); Thymidylate synthase (EC 2.1.1.45)] Length = 518 Score = 345 bits (884), Expect = 8e-95 Identities = 158/188 (84%), Positives = 174/188 (92%) Frame = -1 Query: 613 REEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPT 434 REEGDLGPVYGFQWRHFGA+Y+DMHADYTG+GFDQL DVINKIKNNPDDRRII+SAWNP+ Sbjct: 331 REEGDLGPVYGFQWRHFGAKYTDMHADYTGQGFDQLLDVINKIKNNPDDRRIIMSAWNPS 390 Query: 433 DLKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSP 254 DLK MALPPCHMFAQFYV NGELSCQMYQRSADMGLGVPFNIASYSLLTC++A VCDL P Sbjct: 391 DLKLMALPPCHMFAQFYVANGELSCQMYQRSADMGLGVPFNIASYSLLTCILAHVCDLVP 450 Query: 253 GEFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQ 74 G+F+HVIGDAHVY HV+ L+EQL+ PKPFP+LKINP KKDIDSFVA DF+L YDPH+ Sbjct: 451 GDFIHVIGDAHVYKNHVRPLQEQLENPPKPFPVLKINPEKKDIDSFVADDFELIGYDPHK 510 Query: 73 KIEMKMAV 50 KI+MKMAV Sbjct: 511 KIDMKMAV 518
>DRTS1_ARATH (Q05762) Bifunctional dihydrofolate reductase-thymidylate synthase| 1 (DHFR-TS 1) [Includes: Dihydrofolate reductase (EC 1.5.1.3); Thymidylate synthase (EC 2.1.1.45)] Length = 519 Score = 341 bits (874), Expect = 1e-93 Identities = 157/188 (83%), Positives = 172/188 (91%) Frame = -1 Query: 613 REEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPT 434 REEGDLGPVYGFQWRHFGA+Y+DMHADYTG+GFDQL DVI+KIKNNPDDRRII+SAWNP+ Sbjct: 332 REEGDLGPVYGFQWRHFGAKYTDMHADYTGQGFDQLVDVIDKIKNNPDDRRIIMSAWNPS 391 Query: 433 DLKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSP 254 DLK MALPPCHMFAQFYV GELSCQMYQRSADMGLGVPFNIASYSLLTCM+A VCDL P Sbjct: 392 DLKLMALPPCHMFAQFYVAEGELSCQMYQRSADMGLGVPFNIASYSLLTCMLAHVCDLVP 451 Query: 253 GEFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQ 74 G+F+HV+GDAHVY THV+ L+EQL PKPFP++KINP KK IDSFVASDF L YDPH+ Sbjct: 452 GDFIHVLGDAHVYKTHVRPLQEQLLNLPKPFPVMKINPEKKQIDSFVASDFDLTGYDPHK 511 Query: 73 KIEMKMAV 50 KIEMKMAV Sbjct: 512 KIEMKMAV 519
>DRTS_SOYBN (P51820) Bifunctional dihydrofolate reductase-thymidylate synthase| (DHFR-TS) [Includes: Dihydrofolate reductase (EC 1.5.1.3); Thymidylate synthase (EC 2.1.1.45)] Length = 530 Score = 338 bits (867), Expect = 7e-93 Identities = 155/188 (82%), Positives = 170/188 (90%) Frame = -1 Query: 613 REEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPT 434 REEGDLGPVYGFQWRHFGA Y+DMH DY+G+GFDQL DVINKIK NPDDRRIILSAWNP Sbjct: 343 REEGDLGPVYGFQWRHFGARYTDMHHDYSGQGFDQLLDVINKIKRNPDDRRIILSAWNPV 402 Query: 433 DLKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSP 254 DLK MALPPCHMFAQFYV +GELSCQMYQRSADMGLG+PFNIASY+LLTCMIA VCDL P Sbjct: 403 DLKLMALPPCHMFAQFYVAHGELSCQMYQRSADMGLGIPFNIASYALLTCMIAHVCDLIP 462 Query: 253 GEFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQ 74 G+F+HVIGDAH+Y HV+ L+EQL QPKPFP LKINP KKDIDSFVA+DFKL YDPHQ Sbjct: 463 GDFIHVIGDAHIYRNHVRPLQEQLHNQPKPFPTLKINPKKKDIDSFVAADFKLIGYDPHQ 522 Query: 73 KIEMKMAV 50 KI+MK++V Sbjct: 523 KIDMKLSV 530
>DRTS_DAUCA (P45350) Bifunctional dihydrofolate reductase-thymidylate synthase| (DHFR-TS) [Includes: Dihydrofolate reductase (EC 1.5.1.3); Thymidylate synthase (EC 2.1.1.45)] Length = 528 Score = 319 bits (818), Expect = 4e-87 Identities = 151/189 (79%), Positives = 166/189 (87%), Gaps = 1/189 (0%) Frame = -1 Query: 613 REEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPT 434 REEGDLGP+YGFQWRHFGA Y+DMHADY+G+GFDQL DVI+KIKNNPDDRRII SAWNP+ Sbjct: 340 REEGDLGPIYGFQWRHFGARYTDMHADYSGQGFDQLLDVISKIKNNPDDRRIIQSAWNPS 399 Query: 433 DLKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSP 254 DL+ MALPPCHMFAQFYV NGELSCQMYQRSADMGLGVPFNIA+Y+LLTCMIA VCDL P Sbjct: 400 DLRLMALPPCHMFAQFYVANGELSCQMYQRSADMGLGVPFNIAAYALLTCMIAHVCDLVP 459 Query: 253 GEFVHVIGDAHVYSTHVQAL-EEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPH 77 G+FVH IGDAHVYS H+ L E + PK FP+LKIN +KDIDSF A+DFKL YDPH Sbjct: 460 GDFVHSIGDAHVYSNHLSDLFETSFRMLPKTFPVLKINSGEKDIDSFEAADFKLIGYDPH 519 Query: 76 QKIEMKMAV 50 QKIEMKMAV Sbjct: 520 QKIEMKMAV 528
>TYSY_PNECA (P13100) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 297 Score = 271 bits (694), Expect = 8e-73 Identities = 121/194 (62%), Positives = 151/194 (77%), Gaps = 6/194 (3%) Frame = -1 Query: 613 REEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPT 434 R+EGDLGP+YGFQWRHFGAEY D +Y G+G DQLA++I KI+ +P DRR+ILSAWNP Sbjct: 104 RQEGDLGPIYGFQWRHFGAEYIDCKTNYIGQGVDQLANIIQKIRTSPYDRRLILSAWNPA 163 Query: 433 DLKKMALPPCHMFAQFYVE------NGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQ 272 DL+KMALPPCHMF QFYV ELSCQ+YQRS DMGLGVPFNIASY+LLTCMIA Sbjct: 164 DLEKMALPPCHMFCQFYVHIPSNNHRPELSCQLYQRSCDMGLGVPFNIASYALLTCMIAH 223 Query: 271 VCDLSPGEFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLA 92 VCDL PG+F+HV+GD H+Y H++AL++QL + P+PFP L +N DI+ F DF + Sbjct: 224 VCDLDPGDFIHVMGDCHIYKDHIEALQQQLTRSPRPFPTLSLNRSITDIEDFTLDDFNIQ 283 Query: 91 CYDPHQKIEMKMAV 50 Y P++ I+MKM++ Sbjct: 284 NYHPYETIKMKMSI 297
>TYSY_MOUSE (P07607) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 307 Score = 270 bits (689), Expect = 3e-72 Identities = 124/188 (65%), Positives = 148/188 (78%) Frame = -1 Query: 613 REEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPT 434 R+EGDLGPVYGFQWRHFGAEY DM +DY+G+G DQL VI+ IK NPDDRRII+ AWNP Sbjct: 120 RQEGDLGPVYGFQWRHFGAEYKDMDSDYSGQGVDQLQKVIDTIKTNPDDRRIIMCAWNPK 179 Query: 433 DLKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSP 254 DL MALPPCH QFYV NGELSCQ+YQRS DMGLGVPFNIASY+LLT MIA + L P Sbjct: 180 DLPLMALPPCHALCQFYVVNGELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLQP 239 Query: 253 GEFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQ 74 G+FVH +GDAH+Y H++ L+ QLQ++P+PFP LKI + ID F DF++ Y+PH Sbjct: 240 GDFVHTLGDAHIYLNHIEPLKIQLQREPRPFPKLKILRKVETIDDFKVEDFQIEGYNPHP 299 Query: 73 KIEMKMAV 50 I+M+MAV Sbjct: 300 TIKMEMAV 307
>TYSY_HUMAN (P04818) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 312 Score = 268 bits (685), Expect = 9e-72 Identities = 123/188 (65%), Positives = 148/188 (78%) Frame = -1 Query: 613 REEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPT 434 REEGDLGPVYGFQWRHFGAEY DM +DY+G+G DQL VI+ IK NPDDRRII+ AWNP Sbjct: 125 REEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPR 184 Query: 433 DLKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSP 254 DL MALPPCH QFYV N ELSCQ+YQRS DMGLGVPFNIASY+LLT MIA + L P Sbjct: 185 DLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKP 244 Query: 253 GEFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQ 74 G+F+H +GDAH+Y H++ L+ QLQ++P+PFP L+I + ID F A DF++ Y+PH Sbjct: 245 GDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHP 304 Query: 73 KIEMKMAV 50 I+M+MAV Sbjct: 305 TIKMEMAV 312
>TYSY_RAT (P45352) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 307 Score = 267 bits (683), Expect = 2e-71 Identities = 122/188 (64%), Positives = 148/188 (78%) Frame = -1 Query: 613 REEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPT 434 R+EGDLGPVYGFQWRHFGA+Y DM +DY+G+G DQL VI+ IK NPDDRRII+ AWNP Sbjct: 120 RQEGDLGPVYGFQWRHFGADYKDMDSDYSGQGVDQLQKVIDTIKTNPDDRRIIMCAWNPK 179 Query: 433 DLKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSP 254 DL MALPPCH QFYV NGELSCQ+YQRS DMGLGVPFNIASY+LLT MIA + L P Sbjct: 180 DLPLMALPPCHALCQFYVVNGELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLQP 239 Query: 253 GEFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQ 74 G+FVH +GDAH+Y H++ L+ QLQ++P+PFP L+I + ID F DF++ Y+PH Sbjct: 240 GDFVHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVETIDDFKVEDFQIEGYNPHP 299 Query: 73 KIEMKMAV 50 I+M+MAV Sbjct: 300 TIKMEMAV 307
>TYSY_HHV8 (P90463) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 337 Score = 263 bits (673), Expect = 2e-70 Identities = 121/188 (64%), Positives = 143/188 (76%) Frame = -1 Query: 613 REEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPT 434 R EGDLGPVYGFQWRHFGA Y D ADYTG+GFDQL+ +++ IKNNP DRRII+ AWNP Sbjct: 150 RREGDLGPVYGFQWRHFGAAYVDADADYTGQGFDQLSYIVDLIKNNPHDRRIIMCAWNPA 209 Query: 433 DLKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSP 254 DL MALPPCH+ QFYV +GELSCQ+YQRS DMGLGVPFNIASYSLLT M+A V L P Sbjct: 210 DLSLMALPPCHLLCQFYVADGELSCQLYQRSGDMGLGVPFNIASYSLLTYMLAHVTGLRP 269 Query: 253 GEFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQ 74 GEF+H +GDAH+Y TH++ L QL + P+PFP L+I ++ F DF+L Y PH Sbjct: 270 GEFIHTLGDAHIYKTHIEPLRLQLTRTPRPFPRLEILRSVSSMEEFTPDDFRLVDYCPHP 329 Query: 73 KIEMKMAV 50 I M+MAV Sbjct: 330 TIRMEMAV 337
>DRTS_PLACH (P20712) Bifunctional dihydrofolate reductase-thymidylate synthase| (DHFR-TS) [Includes: Dihydrofolate reductase (EC 1.5.1.3); Thymidylate synthase (EC 2.1.1.45)] Length = 583 Score = 262 bits (669), Expect = 7e-70 Identities = 122/187 (65%), Positives = 146/187 (78%) Frame = -1 Query: 613 REEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPT 434 RE DLGP+YGFQWRHFGAEY+DMHADY KG DQL ++IN IKN+P RRIIL AWN Sbjct: 396 REVNDLGPIYGFQWRHFGAEYTDMHADYKDKGVDQLKNIINLIKNDPTCRRIILCAWNVK 455 Query: 433 DLKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSP 254 DL +MALPPCH+ QFYV +G+LSC MYQRS D+GLGVPFNIASYS+ T MIAQVC+L P Sbjct: 456 DLDQMALPPCHILCQFYVFDGKLSCIMYQRSCDLGLGVPFNIASYSIFTYMIAQVCNLQP 515 Query: 253 GEFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQ 74 EF+HV+G+AHVY+ HV++L+ QL + P PFP LK+NP K+I+ F SDF + Y H Sbjct: 516 AEFIHVLGNAHVYNNHVESLKVQLNRTPYPFPTLKLNPEIKNIEDFTISDFTVQNYVHHD 575 Query: 73 KIEMKMA 53 KI M MA Sbjct: 576 KISMDMA 582
>DRTS_PARTE (Q27828) Bifunctional dihydrofolate reductase-thymidylate synthase| (DHFR-TS) [Includes: Dihydrofolate reductase (EC 1.5.1.3); Thymidylate synthase (EC 2.1.1.45)] Length = 462 Score = 261 bits (668), Expect = 9e-70 Identities = 118/188 (62%), Positives = 150/188 (79%) Frame = -1 Query: 613 REEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPT 434 R+E DLGPVYGFQWRHFGA+Y D DY+ +G DQ+ ++I +KNNPD RRIILSAWNP Sbjct: 276 RQEHDLGPVYGFQWRHFGAKYKDCQTDYSNQGVDQVKEIIQLLKNNPDSRRIILSAWNPI 335 Query: 433 DLKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSP 254 DLK+MALPPCH+ +QF+V NG+LSC MYQRS D GLG+PFNIASY+LLT M+A+ C+L+ Sbjct: 336 DLKQMALPPCHVMSQFFVANGKLSCMMYQRSCDFGLGIPFNIASYALLTYMLAKECNLNL 395 Query: 253 GEFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQ 74 GEFVHV+GD H+YS HV+AL++Q+++ P PFP+LKI K + + DF+L Y+ H Sbjct: 396 GEFVHVLGDTHIYSNHVEALKKQIERVPYPFPLLKIKG-NKSLFDYTYEDFELVGYNAHD 454 Query: 73 KIEMKMAV 50 KIEMKMAV Sbjct: 455 KIEMKMAV 462
>TYSY_YEAST (P06785) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 304 Score = 261 bits (667), Expect = 1e-69 Identities = 124/197 (62%), Positives = 151/197 (76%), Gaps = 9/197 (4%) Frame = -1 Query: 613 REEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPT 434 R+ GDLGPVYGFQWRHFGA+Y DYTG+G DQL VI+K+K NP DRRII+SAWNP Sbjct: 108 RKVGDLGPVYGFQWRHFGAKYKTCDDDYTGQGIDQLKQVIHKLKTNPYDRRIIMSAWNPA 167 Query: 433 DLKKMALPPCHMFAQFYV---ENGE------LSCQMYQRSADMGLGVPFNIASYSLLTCM 281 D KMALPPCH+F+QFYV + GE LSC +YQRS DMGLGVPFNIASY+LLT M Sbjct: 168 DFDKMALPPCHIFSQFYVSFPKEGEGSGKPRLSCLLYQRSCDMGLGVPFNIASYALLTRM 227 Query: 280 IAQVCDLSPGEFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDF 101 IA+V D+ PGEF+H +GDAHVY H+ AL+EQ+ + P+PFP LKI KDID F +DF Sbjct: 228 IAKVVDMEPGEFIHTLGDAHVYKDHIDALKEQITRNPRPFPKLKIKRDVKDIDDFKLTDF 287 Query: 100 KLACYDPHQKIEMKMAV 50 ++ Y+PH +I+MKM+V Sbjct: 288 EIEDYNPHPRIQMKMSV 304
>TYSY_EHV2 (Q89940) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 289 Score = 260 bits (665), Expect = 2e-69 Identities = 121/188 (64%), Positives = 142/188 (75%) Frame = -1 Query: 613 REEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPT 434 RE GDLGPVYGFQWRHFGA Y D DY G+G DQL D+I +IK NP+ RR++L+AWNP Sbjct: 102 REPGDLGPVYGFQWRHFGAAYVDSKTDYRGQGVDQLRDLIGEIKRNPESRRLVLTAWNPA 161 Query: 433 DLKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSP 254 DL MALPPCH+ QFYV GELSCQ+YQRS DMGLGVPFNIASYSLLT M+A + L P Sbjct: 162 DLPAMALPPCHLLCQFYVAGGELSCQLYQRSGDMGLGVPFNIASYSLLTYMVAHLTGLEP 221 Query: 253 GEFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQ 74 G+F+HV+GDAHVY HV+ L+ QL + P+PFP L+I +DID F A DF L Y PH Sbjct: 222 GDFIHVLGDAHVYLNHVEPLKLQLTRSPRPFPRLRILRRVEDIDDFRAEDFALEGYHPHA 281 Query: 73 KIEMKMAV 50 I M+MAV Sbjct: 282 AIPMEMAV 289
>TYSY_DROME (O76511) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 321 Score = 260 bits (665), Expect = 2e-69 Identities = 124/190 (65%), Positives = 146/190 (76%), Gaps = 2/190 (1%) Frame = -1 Query: 613 REEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPT 434 R GDLGPVYGFQWRHFGA+Y DY+GKG DQL VI+ I+NNP DRRII+SAWNP Sbjct: 132 RAVGDLGPVYGFQWRHFGAQYGTCDDDYSGKGIDQLRQVIDTIRNNPSDRRIIMSAWNPL 191 Query: 433 DLKKMALPPCHMFAQFYV--ENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDL 260 D+ KMALPPCH AQFYV + GELSCQ+YQRSADMGLGVPFNIASY+LLT MIA V L Sbjct: 192 DIPKMALPPCHCLAQFYVSEKRGELSCQLYQRSADMGLGVPFNIASYALLTHMIAHVTGL 251 Query: 259 SPGEFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDP 80 PG+FVH +GD HVY HV+ L+EQL++ P+PFP L I +DI+ F DF++ Y+P Sbjct: 252 KPGDFVHTMGDTHVYLNHVEPLKEQLERTPRPFPKLIIKRQVQDIEDFRFEDFQIVDYNP 311 Query: 79 HQKIEMKMAV 50 H KI+M MAV Sbjct: 312 HPKIQMDMAV 321
>TYSY_HSVAT (P12462) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 290 Score = 259 bits (661), Expect = 6e-69 Identities = 122/188 (64%), Positives = 143/188 (76%) Frame = -1 Query: 613 REEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPT 434 REEGDLGPVYGFQWRHFGAEY + +Y G+G DQL +IN I NP DRR+++ AWN Sbjct: 103 REEGDLGPVYGFQWRHFGAEYQGLKHNYGGEGVDQLKQIINTIHTNPTDRRMLMCAWNVL 162 Query: 433 DLKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSP 254 D+ KMALPPCH+ +QFYV +G+LSCQ+YQRSADMGLGVPFNIASYSLLTCMIA V DL P Sbjct: 163 DVPKMALPPCHVLSQFYVCDGKLSCQLYQRSADMGLGVPFNIASYSLLTCMIAHVTDLVP 222 Query: 253 GEFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQ 74 GEF+H +GDAHVY HV AL EQL + P+PFP LK ID F A+D L Y+P+ Sbjct: 223 GEFIHTLGDAHVYVNHVDALTEQLTRTPRPFPTLKFARKVASIDDFKANDIILENYNPYP 282 Query: 73 KIEMKMAV 50 I+M MAV Sbjct: 283 SIKMPMAV 290
>DRTS_TOXGO (Q07422) Bifunctional dihydrofolate reductase-thymidylate synthase| (DHFR-TS) [Includes: Dihydrofolate reductase (EC 1.5.1.3); Thymidylate synthase (EC 2.1.1.45)] Length = 610 Score = 254 bits (650), Expect = 1e-67 Identities = 117/191 (61%), Positives = 149/191 (78%), Gaps = 3/191 (1%) Frame = -1 Query: 613 REEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPT 434 RE GD+GP YGFQWRHFGA Y DMH DYTG+G DQL +VI ++ NP DRR++++AWNP Sbjct: 420 REVGDIGPGYGFQWRHFGAAYKDMHTDYTGQGVDQLKNVIQMLRTNPTDRRMLMTAWNPA 479 Query: 433 DLKKMALPPCHMFAQFYV-ENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLS 257 L +MALPPCH+ QFYV + ELSC MYQRS D+GLGVPFNIASYSLLT M+A VC+L Sbjct: 480 ALDEMALPPCHLLCQFYVNDQKELSCIMYQRSCDVGLGVPFNIASYSLLTLMVAHVCNLK 539 Query: 256 PGEFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKI--NPLKKDIDSFVASDFKLACYD 83 P EF+H +G+ HVY+ HV+AL+EQL+++P+PFPI+ I K+ID F A DF++ Y Sbjct: 540 PKEFIHFMGNTHVYTNHVEALKEQLRREPRPFPIVNILNKERIKEIDDFTAEDFEVVGYV 599 Query: 82 PHQKIEMKMAV 50 PH +I+M+MAV Sbjct: 600 PHGRIQMEMAV 610
>TYSY_SHV21 (P06854) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 294 Score = 253 bits (646), Expect = 3e-67 Identities = 118/188 (62%), Positives = 143/188 (76%) Frame = -1 Query: 613 REEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPT 434 R+EGDLGPVYGFQWRHFGAEY + DY G+G DQL +I+ IK NP DRR+++ AWN + Sbjct: 107 RDEGDLGPVYGFQWRHFGAEYKGVGRDYKGEGVDQLKQLIDTIKTNPTDRRMLMCAWNVS 166 Query: 433 DLKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSP 254 D+ KM LPPCH+ +QFYV +G+LSCQ+YQRSADMGLGVPFNIASYSLLTCMIA V +L P Sbjct: 167 DIPKMVLPPCHVLSQFYVCDGKLSCQLYQRSADMGLGVPFNIASYSLLTCMIAHVTNLVP 226 Query: 253 GEFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQ 74 GEF+H IGDAH+Y H+ AL+ QL + P+PFP L+ ID F A D L Y+PH Sbjct: 227 GEFIHTIGDAHIYVDHIDALKMQLTRTPRPFPTLRFARNVSCIDDFKADDIILENYNPHP 286 Query: 73 KIEMKMAV 50 I+M MAV Sbjct: 287 IIKMHMAV 294
>DRTS_PLAVI (O02604) Bifunctional dihydrofolate reductase-thymidylate synthase| (DHFR-TS) [Includes: Dihydrofolate reductase (EC 1.5.1.3); Thymidylate synthase (EC 2.1.1.45)] Length = 623 Score = 253 bits (645), Expect = 4e-67 Identities = 117/187 (62%), Positives = 144/187 (77%) Frame = -1 Query: 613 REEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPT 434 RE DLGP+YGFQWRHFGAEY++MH +Y KG DQL +VI+ IKN P RRIIL AWN Sbjct: 436 REVNDLGPIYGFQWRHFGAEYTNMHDNYEDKGVDQLKNVIHLIKNEPTSRRIILCAWNVK 495 Query: 433 DLKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSP 254 DL +MALPPCH+ QFYV +G+LSC MYQRS D+GLGVPFNIASYS+ T MIAQVC+L P Sbjct: 496 DLDQMALPPCHILCQFYVFDGKLSCIMYQRSCDLGLGVPFNIASYSIFTHMIAQVCNLQP 555 Query: 253 GEFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQ 74 +F+H++G+AHVY+ HV +L+ QL + P PFP LK+NP K+I+ F SDF + Y H Sbjct: 556 AQFIHILGNAHVYNNHVDSLKVQLNRIPYPFPTLKLNPEVKNIEDFTISDFTIENYVHHD 615 Query: 73 KIEMKMA 53 KI M+MA Sbjct: 616 KITMEMA 622
>DRTS_PLABA (Q27713) Bifunctional dihydrofolate reductase-thymidylate synthase| (DHFR-TS) [Includes: Dihydrofolate reductase (EC 1.5.1.3); Thymidylate synthase (EC 2.1.1.45)] Length = 587 Score = 251 bits (642), Expect = 9e-67 Identities = 117/187 (62%), Positives = 144/187 (77%) Frame = -1 Query: 613 REEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPT 434 RE DLGP+YGFQWRHFGAEY+DMH +Y KG DQL ++IN IKN+P RRIIL AWN Sbjct: 400 REVNDLGPIYGFQWRHFGAEYTDMHDNYKDKGVDQLKNIINLIKNDPTCRRIILCAWNVK 459 Query: 433 DLKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSP 254 +L +MALPPCH+ QFYV +G+LSC MYQRS D+GLGVPFNIASYS+ T MIAQVC+L Sbjct: 460 NLDQMALPPCHILCQFYVFDGKLSCIMYQRSCDLGLGVPFNIASYSIFTYMIAQVCNLQA 519 Query: 253 GEFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQ 74 EF+HV+G+AHVY+ H+++L+ QL + P PFP LK+NP K+I+ F SDF + Y H Sbjct: 520 AEFIHVLGNAHVYNNHIESLKIQLNRTPYPFPTLKLNPDIKNIEDFTISDFTVQNYVHHD 579 Query: 73 KIEMKMA 53 KI M MA Sbjct: 580 KINMDMA 586
>DRTS_PLAFK (P13922) Bifunctional dihydrofolate reductase-thymidylate synthase| (DHFR-TS) [Includes: Dihydrofolate reductase (EC 1.5.1.3); Thymidylate synthase (EC 2.1.1.45)] Length = 608 Score = 251 bits (641), Expect = 1e-66 Identities = 115/187 (61%), Positives = 145/187 (77%) Frame = -1 Query: 613 REEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPT 434 RE DLGP+YGFQWRHFGAEY++M+ +Y KG DQL ++IN IKN+P RRI+L AWN Sbjct: 421 REVNDLGPIYGFQWRHFGAEYTNMYDNYENKGVDQLKNIINLIKNDPTSRRILLCAWNVK 480 Query: 433 DLKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSP 254 DL +MALPPCH+ QFYV +G+LSC MYQRS D+GLGVPFNIASYS+ T MIAQVC+L P Sbjct: 481 DLDQMALPPCHILCQFYVFDGKLSCIMYQRSCDLGLGVPFNIASYSIFTHMIAQVCNLQP 540 Query: 253 GEFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQ 74 +F+HV+G+AHVY+ H+ +L+ QL + P PFP LK+NP K+I+ F SDF + Y H+ Sbjct: 541 AQFIHVLGNAHVYNNHIDSLKIQLNRIPYPFPTLKLNPDIKNIEDFTISDFTIQNYVHHE 600 Query: 73 KIEMKMA 53 KI M MA Sbjct: 601 KISMDMA 607
>TYSY_CANAL (P12461) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 314 Score = 249 bits (635), Expect = 6e-66 Identities = 123/209 (58%), Positives = 146/209 (69%), Gaps = 21/209 (10%) Frame = -1 Query: 613 REEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPT 434 R EGDLGPVYGFQWRHFGAEY D +DYTG+GFDQL DVI K+K NP DRRII+SAWNP Sbjct: 106 RREGDLGPVYGFQWRHFGAEYKDCDSDYTGQGFDQLQDVIKKLKTNPYDRRIIMSAWNPP 165 Query: 433 DLKKMALPPCHMFAQFYVE-----------------NGELSCQMYQRSADMGLGVPFNIA 305 D KMALPPCH+F QFYV +LSC +YQRS DMGLGVPFNIA Sbjct: 166 DFAKMALPPCHVFCQFYVNFPTSSPDPNNPKQAKTAKPKLSCLLYQRSCDMGLGVPFNIA 225 Query: 304 SYSLLTCMIAQVCDLSPGEFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKD- 128 SY+LLT MIA V D+ GEF+H +GDAHVY H+ AL+EQ ++ PK FP L I +K+ Sbjct: 226 SYALLTKMIAHVVDMDCGEFIHTLGDAHVYLDHIDALKEQFERIPKQFPKLVIKEERKNE 285 Query: 127 ---IDSFVASDFKLACYDPHQKIEMKMAV 50 ID F DF++ Y+P+ I+MKM+V Sbjct: 286 IKSIDDFKFEDFEIVGYEPYPPIKMKMSV 314
>TYSY_ASCSU (O96650) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 294 Score = 248 bits (634), Expect = 8e-66 Identities = 120/188 (63%), Positives = 137/188 (72%) Frame = -1 Query: 613 REEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPT 434 R EGDLGP+YGFQWRHFGAEY ADY G+G DQLADVI +IKNNP+ RRIIL+AWN Sbjct: 107 RPEGDLGPIYGFQWRHFGAEYHGTDADYKGQGVDQLADVIEQIKNNPNSRRIILNAWNVK 166 Query: 433 DLKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSP 254 DL +MALPPCH AQF V+NGELSCQ+YQRS DMGLGVPFN+ASY LLT MIA VC L Sbjct: 167 DLHQMALPPCHTLAQFAVKNGELSCQLYQRSGDMGLGVPFNLASYGLLTHMIAHVCALKT 226 Query: 253 GEFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQ 74 G HV+GDAHVY H+ AL+EQL + P+PFP + ID F A L Y+P Sbjct: 227 GFLHHVLGDAHVYLNHIDALKEQLSRDPRPFPTVHFEGRIDSIDDFTAESIILNGYNPMA 286 Query: 73 KIEMKMAV 50 I+M MAV Sbjct: 287 PIKMPMAV 294
>TYSY_AGABI (Q9P4T7) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 296 Score = 241 bits (615), Expect = 1e-63 Identities = 121/195 (62%), Positives = 139/195 (71%), Gaps = 7/195 (3%) Frame = -1 Query: 613 REEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPT 434 R EGDLGPVYGFQWRHFGAEY D ADY GKG DQL + I KIK NP DRRIILSAWNP Sbjct: 102 RREGDLGPVYGFQWRHFGAEYEDCDADYAGKGVDQLRECIRKIKENPTDRRIILSAWNPK 161 Query: 433 DLKKMALPPCHMFAQFYVE------NGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQ 272 D+ MALPPCHM QFYV ELSC M+QRSAD+GLG+PFNIASY+LLT MIA Sbjct: 162 DIPSMALPPCHMLCQFYVHLPADTAKPELSCLMFQRSADLGLGIPFNIASYALLTHMIAH 221 Query: 271 VCDLSPGEFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILK-INPLKKDIDSFVASDFKL 95 V + E + +GDAHVY HV+ALE QLQ++P+PFP L+ DI+ F SDF + Sbjct: 222 VTGTTARELIIQLGDAHVYRDHVEALEVQLQREPRPFPKLRWARDGITDIEDFEYSDFVI 281 Query: 94 ACYDPHQKIEMKMAV 50 Y+PH I MKM+V Sbjct: 282 EGYNPHPSIAMKMSV 296
>TYSY_VZVD (P09249) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 301 Score = 240 bits (613), Expect = 2e-63 Identities = 109/188 (57%), Positives = 137/188 (72%) Frame = -1 Query: 613 REEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPT 434 R GDLGP+YGFQWRHFGAEY D ++Y +G DQL VI+ IK NP+ RR+I+S+WNP Sbjct: 114 RHTGDLGPIYGFQWRHFGAEYKDCQSNYLQQGIDQLQTVIDTIKTNPESRRMIISSWNPK 173 Query: 433 DLKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSP 254 D+ M LPPCH QFYV NGELSCQ+YQRS DMGLGVPFNIA Y+LLT ++A V L Sbjct: 174 DIPLMVLPPCHTLCQFYVANGELSCQVYQRSGDMGLGVPFNIAGYALLTYIVAHVTGLKT 233 Query: 253 GEFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQ 74 G+ +H +GDAH+Y H+ AL+ QL + PKPFP LKI DI+ F DF+L Y+PH Sbjct: 234 GDLIHTMGDAHIYLNHIDALKVQLARSPKPFPCLKIIRNVTDINDFKWDDFQLDGYNPHP 293 Query: 73 KIEMKMAV 50 ++M+MA+ Sbjct: 294 PLKMEMAL 301
>TYS1_ENCCU (O62584) Thymidylate synthase 1/2 (EC 2.1.1.45) (TS 1/2) (TSase| 1/2) Length = 294 Score = 239 bits (610), Expect = 5e-63 Identities = 112/189 (59%), Positives = 138/189 (73%), Gaps = 2/189 (1%) Frame = -1 Query: 613 REEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPT 434 REEGDLGP+YGFQWRHFGA Y + Y GKG DQ+A I I+ NP RRI++SAWNPT Sbjct: 105 REEGDLGPIYGFQWRHFGARYETSASSYEGKGVDQIASAIAAIRANPASRRIVVSAWNPT 164 Query: 433 DLKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSP 254 DL MALPPCH+ QF V +G+LSC MYQRS DMGLGVPFNIASYSLLT ++A + L P Sbjct: 165 DLGSMALPPCHVLFQFNVTDGKLSCAMYQRSGDMGLGVPFNIASYSLLTILVAHLTGLQP 224 Query: 253 GEFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPL--KKDIDSFVASDFKLACYDP 80 GEFVH +GDAHVY HV +L +Q+Q+ P+ FP L ++P + + + F DF+L YDP Sbjct: 225 GEFVHFLGDAHVYLDHVDSLRQQIQRPPRAFPKLFVSPKGPRTEPEHFQYEDFELVGYDP 284 Query: 79 HQKIEMKMA 53 H I+M M+ Sbjct: 285 HPAIKMNMS 293
>TYS3_ENCCU (Q8SRG2) Thymidylate synthase 3 (EC 2.1.1.45) (TS 3) (TSase 3)| Length = 294 Score = 239 bits (609), Expect = 6e-63 Identities = 112/189 (59%), Positives = 138/189 (73%), Gaps = 2/189 (1%) Frame = -1 Query: 613 REEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPT 434 REEGDLGP+YGFQWRHFGA Y + Y GKG DQ+A I I+ NP RRI++SAWNPT Sbjct: 105 REEGDLGPIYGFQWRHFGARYETSASSYEGKGVDQIASAIAAIRANPASRRIVVSAWNPT 164 Query: 433 DLKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSP 254 DL MALPPCH+ QF V +G+LSC MYQRS DMGLGVPFNIASYSLLT ++A + L P Sbjct: 165 DLGSMALPPCHVLFQFNVTDGKLSCAMYQRSGDMGLGVPFNIASYSLLTILVAHLTGLQP 224 Query: 253 GEFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPL--KKDIDSFVASDFKLACYDP 80 GEFVH +GDAHVY HV +L +Q+Q+ P+ FP L ++P + + + F DF+L YDP Sbjct: 225 GEFVHFLGDAHVYLDHVDSLRQQVQRPPRAFPKLFVSPKGPRTEPEHFQYEDFELVGYDP 284 Query: 79 HQKIEMKMA 53 H I+M M+ Sbjct: 285 HPAIKMNMS 293
>DRTS_TRYBB (Q27783) Bifunctional dihydrofolate reductase-thymidylate synthase| (DHFR-TS) [Includes: Dihydrofolate reductase (EC 1.5.1.3); Thymidylate synthase (EC 2.1.1.45)] Length = 527 Score = 238 bits (607), Expect = 1e-62 Identities = 108/187 (57%), Positives = 137/187 (73%) Frame = -1 Query: 610 EEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTD 431 +E DLGPVYGFQWRHFGA+Y D GKG DQ+A+++ + NPDDRR+I +AWNP Sbjct: 341 DEMDLGPVYGFQWRHFGADYISCKVDSEGKGVDQIANIVKSLIENPDDRRMICTAWNPAA 400 Query: 430 LKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPG 251 L +MALPPCHM AQFYV NGELSC +YQRS DMGLGVPFNIASY+LLT ++A+ L PG Sbjct: 401 LPRMALPPCHMMAQFYVSNGELSCMLYQRSCDMGLGVPFNIASYALLTFLMAKASGLRPG 460 Query: 250 EFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQK 71 E VH +GDAHVYS HV+ +QL++ P+PFP + K+ ++ F SD ++ Y P+ Sbjct: 461 ELVHTLGDAHVYSNHVEPCRKQLKRVPRPFPFIVFKQDKEFLEDFQESDIEVIDYSPYPV 520 Query: 70 IEMKMAV 50 I M+MAV Sbjct: 521 ISMEMAV 527
>TYSY_CRYNE (P45351) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 317 Score = 238 bits (606), Expect = 1e-62 Identities = 121/199 (60%), Positives = 140/199 (70%), Gaps = 12/199 (6%) Frame = -1 Query: 613 REEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPT 434 R EGDLGPVYGFQWRHFGAEY+D DY GKG DQL VI+ IKNNP DRRIILSAWNP Sbjct: 118 RREGDLGPVYGFQWRHFGAEYTDADGDYKGKGVDQLQRVIDTIKNNPTDRRIILSAWNPK 177 Query: 433 DLKKMALPPCHMFAQFYV---------ENGELSCQMYQRSADMGLGVPFNIASYSLLTCM 281 DL MALPPCHMF QF+V +LSC MYQRS D+GLGVPFNIASY+LLT M Sbjct: 178 DLPLMALPPCHMFCQFFVSLPPADSPGSKPKLSCLMYQRSCDLGLGVPFNIASYALLTHM 237 Query: 280 IAQVCDLSPGEFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKK---DIDSFVA 110 IA + D P EF+ +GDAHVY HV+ L+ QL+++P+ FP LK K+ DID F Sbjct: 238 IALITDTEPHEFILQMGDAHVYRDHVEPLKTQLEREPRDFPKLKWARSKEEIGDIDGFKV 297 Query: 109 SDFKLACYDPHQKIEMKMA 53 DF + Y P KI+MKM+ Sbjct: 298 EDFVVEGYKPWGKIDMKMS 316
>DRTS_TRYCR (Q27793) Bifunctional dihydrofolate reductase-thymidylate synthase| (DHFR-TS) [Includes: Dihydrofolate reductase (EC 1.5.1.3); Thymidylate synthase (EC 2.1.1.45)] Length = 521 Score = 236 bits (602), Expect = 4e-62 Identities = 107/187 (57%), Positives = 137/187 (73%) Frame = -1 Query: 610 EEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTD 431 EE DLGPVYGFQWRHFGA Y+ A+Y G+G DQ+ ++ +K NPDDRR++ +AWNP+ Sbjct: 335 EEMDLGPVYGFQWRHFGAAYTHHDANYDGQGVDQIKAIVETLKTNPDDRRMLFTAWNPSA 394 Query: 430 LKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPG 251 L +MALPPCH+ AQFYV NGELSC +YQRS DMGLGVPFNIASY+LLT +IA+ L PG Sbjct: 395 LPRMALPPCHLLAQFYVSNGELSCMLYQRSCDMGLGVPFNIASYALLTILIAKATGLRPG 454 Query: 250 EFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQK 71 E VH +GDAHVYS HV+ EQL++ P+ FP L ++ ++ + D ++ Y P+ Sbjct: 455 ELVHTLGDAHVYSNHVEPCNEQLKRVPRAFPYLVFRREREFLEDYEEGDMEVIDYAPYPP 514 Query: 70 IEMKMAV 50 I MKMAV Sbjct: 515 ISMKMAV 521
>DRTS_LEIAM (P16126) Bifunctional dihydrofolate reductase-thymidylate synthase| (DHFR-TS) [Includes: Dihydrofolate reductase (EC 1.5.1.3); Thymidylate synthase (EC 2.1.1.45)] Length = 520 Score = 228 bits (580), Expect = 1e-59 Identities = 106/188 (56%), Positives = 136/188 (72%), Gaps = 2/188 (1%) Frame = -1 Query: 607 EGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTDL 428 E DLGPVYGFQWRHFGAEY + A+Y G+G DQ+ ++ IK NP+DRR++ +AWNP L Sbjct: 333 EMDLGPVYGFQWRHFGAEYRGLEANYDGEGVDQIKFIVETIKANPNDRRLLFTAWNPCAL 392 Query: 427 KKMALPPCHMFAQFYV--ENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSP 254 KMALPPCH+ AQFYV E ELSC +YQRS DMGLGVPFNIASY+LLT +IA+ L P Sbjct: 393 HKMALPPCHLLAQFYVNTEKSELSCMLYQRSCDMGLGVPFNIASYALLTILIAKATGLRP 452 Query: 253 GEFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQ 74 GE VH +GDAHVY +H+ AL+ QL++ P FP L ++ ++ + D ++ Y PH Sbjct: 453 GELVHTLGDAHVYRSHIDALKAQLERVPHAFPTLVFKEERQFLEDYELMDMEVIDYVPHP 512 Query: 73 KIEMKMAV 50 I+M+MAV Sbjct: 513 PIKMEMAV 520
>DRTS_LEIMA (P07382) Bifunctional dihydrofolate reductase-thymidylate synthase| (DHFR-TS) [Includes: Dihydrofolate reductase (EC 1.5.1.3); Thymidylate synthase (EC 2.1.1.45)] Length = 520 Score = 227 bits (579), Expect = 2e-59 Identities = 105/189 (55%), Positives = 138/189 (73%), Gaps = 2/189 (1%) Frame = -1 Query: 610 EEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTD 431 +E DLGPVYGFQWRHFGA+Y A+Y G+G DQ+ ++ IK NP+DRR++++AWNP Sbjct: 332 KEMDLGPVYGFQWRHFGADYKGFEANYDGEGVDQIKLIVETIKTNPNDRRLLVTAWNPCA 391 Query: 430 LKKMALPPCHMFAQFYV--ENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLS 257 L+KMALPPCH+ AQFYV + ELSC +YQRS DMGLGVPFNIASY+LLT +IA+ L Sbjct: 392 LQKMALPPCHLLAQFYVNTDTSELSCMLYQRSCDMGLGVPFNIASYALLTILIAKATGLR 451 Query: 256 PGEFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPH 77 PGE VH +GDAHVY HV AL+ QL++ P FP L ++ ++ + +D ++ Y PH Sbjct: 452 PGELVHTLGDAHVYRNHVDALKAQLERVPHAFPTLIFKEERQYLEDYELTDMEVIDYVPH 511 Query: 76 QKIEMKMAV 50 I+M+MAV Sbjct: 512 PAIKMEMAV 520
>TYSY_CHRVO (Q7NZ95) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 264 Score = 224 bits (570), Expect = 2e-58 Identities = 104/187 (55%), Positives = 134/187 (71%) Frame = -1 Query: 610 EEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTD 431 E GDLGPVYG+QWR + A G+ DQ++ +++ IK NPD RR+I+SAWNP Sbjct: 86 ENGDLGPVYGYQWRSWPAP--------DGRHIDQISQLLDMIKKNPDSRRLIVSAWNPAL 137 Query: 430 LKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPG 251 + +MALPPCH QFYV NG LSCQ+YQRSAD+ LGVPFNIASY+LLT M+AQVC L PG Sbjct: 138 VDQMALPPCHSLFQFYVANGRLSCQLYQRSADIFLGVPFNIASYALLTMMVAQVCGLQPG 197 Query: 250 EFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQK 71 +FVH +GDAH+YS H++ QL + P+P P +K+NP KD+ +F DF L YDPH Sbjct: 198 DFVHTLGDAHLYSNHLEQARLQLTRDPRPLPTMKLNPEVKDLFAFTFDDFALEGYDPHPH 257 Query: 70 IEMKMAV 50 I+ ++AV Sbjct: 258 IKAQVAV 264
>TYSY_BRAJA (Q89G35) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 264 Score = 221 bits (563), Expect = 1e-57 Identities = 105/185 (56%), Positives = 134/185 (72%) Frame = -1 Query: 604 GDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTDLK 425 GDLGPVYG QWR + A G+ DQ+A+V++ IK NPD RR+I+SAWNP ++ Sbjct: 88 GDLGPVYGHQWRSWPAP--------DGRSIDQIANVVDMIKRNPDSRRLIVSAWNPAEVD 139 Query: 424 KMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPGEF 245 KMALPPCH QFYV NG+LSCQ+YQRSAD+ LGVPFNIASY+LLT M+AQV L PG+F Sbjct: 140 KMALPPCHCLFQFYVANGKLSCQLYQRSADVFLGVPFNIASYALLTMMVAQVTGLKPGDF 199 Query: 244 VHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQKIE 65 VH GD H+YS H++ + QL + P+ P+++INP KDI SF DF+L YDPH I+ Sbjct: 200 VHSFGDTHLYSNHLEQAKLQLTRAPRALPVMRINPDVKDIFSFRFEDFELVGYDPHPHIK 259 Query: 64 MKMAV 50 ++AV Sbjct: 260 AEVAV 264
>TYSY_NEIMB (Q9JY72) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 264 Score = 220 bits (560), Expect = 3e-57 Identities = 104/187 (55%), Positives = 135/187 (72%) Frame = -1 Query: 610 EEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTD 431 E GDLGPVYG+QWR++ A G+ DQ+A+V+ +IK NPD RR+I+SAWNP Sbjct: 86 ENGDLGPVYGYQWRNWPAP--------DGRHIDQIANVLEQIKKNPDSRRLIVSAWNPAL 137 Query: 430 LKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPG 251 + +MALPPCH QFYV +G+LSCQ+YQRSAD+ LGVPFNIASY+LLT M+AQVC L G Sbjct: 138 VDEMALPPCHALFQFYVADGKLSCQLYQRSADIFLGVPFNIASYALLTMMMAQVCGLEAG 197 Query: 250 EFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQK 71 EFVH GDAH+Y H + QL+++P+ P++KINP KD+ SF DF+L YDPH Sbjct: 198 EFVHTFGDAHLYRNHFEQAALQLEREPRALPVMKINPEVKDLFSFKFEDFELEGYDPHPH 257 Query: 70 IEMKMAV 50 I+ ++V Sbjct: 258 IKAAVSV 264
>TYSY_RHOPA (Q6N447) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 264 Score = 219 bits (558), Expect = 5e-57 Identities = 106/185 (57%), Positives = 132/185 (71%) Frame = -1 Query: 604 GDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTDLK 425 GDLGPVYG QWR + AD G DQ+A+V+ IK NPD RR++++AWNP D++ Sbjct: 88 GDLGPVYGAQWRSWPT------AD--GGSIDQIANVVEMIKRNPDSRRLMVTAWNPADVE 139 Query: 424 KMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPGEF 245 KMALPPCH QFYV NG+LSCQ+YQRSAD+ LGVPFNIASY+LLT M+AQV L PGEF Sbjct: 140 KMALPPCHCLFQFYVANGKLSCQLYQRSADVFLGVPFNIASYALLTLMVAQVTGLKPGEF 199 Query: 244 VHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQKIE 65 VH +GDAH+YS H++ QL + P+ P++ INP KDI F DF L YDPH I+ Sbjct: 200 VHTLGDAHLYSNHLEQARLQLTRAPRALPVMTINPAVKDIFGFRYEDFTLTGYDPHPHIK 259 Query: 64 MKMAV 50 ++AV Sbjct: 260 AEVAV 264
>TYSY_NEIMA (Q9JT57) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 264 Score = 219 bits (557), Expect = 6e-57 Identities = 103/187 (55%), Positives = 135/187 (72%) Frame = -1 Query: 610 EEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTD 431 E GDLGPVYG+QWR++ A G+ DQ+A+V+ +IK NPD RR+I+SAWNP Sbjct: 86 ENGDLGPVYGYQWRNWPAP--------DGRHIDQIANVLEQIKKNPDSRRLIVSAWNPAL 137 Query: 430 LKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPG 251 + +MALPPCH QFYV +G+LSCQ+YQRSAD+ LGVPFNIASY+LLT M+AQVC L G Sbjct: 138 VDEMALPPCHALFQFYVADGKLSCQLYQRSADIFLGVPFNIASYALLTMMMAQVCGLEAG 197 Query: 250 EFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQK 71 EFVH GDAH+Y H + QL+++P+ P++KINP KD+ +F DF+L YDPH Sbjct: 198 EFVHTFGDAHLYRNHFEQAALQLEREPRALPVMKINPEVKDLFAFKFEDFELEGYDPHPH 257 Query: 70 IEMKMAV 50 I+ ++V Sbjct: 258 IKAAVSV 264
>TYSY_NEIGO (O33380) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 265 Score = 218 bits (554), Expect = 1e-56 Identities = 103/187 (55%), Positives = 133/187 (71%) Frame = -1 Query: 610 EEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTD 431 E GDLGPVYG+QWR + A G+ DQ+A+V+ +IK NPD RR+I+SAWNP Sbjct: 87 ENGDLGPVYGYQWRSWPAP--------DGRHIDQIANVVEQIKKNPDSRRLIVSAWNPAL 138 Query: 430 LKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPG 251 + +MALPPCH QFYV +G LSCQ+YQRSAD+ LGVPFNIASY+LLT M+AQVC L G Sbjct: 139 VDEMALPPCHALFQFYVADGNLSCQLYQRSADIFLGVPFNIASYALLTMMMAQVCGLEAG 198 Query: 250 EFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQK 71 EFVH GDAH+Y H + QL+++P+ P++KINP KD+ +F DF+L YDPH Sbjct: 199 EFVHTFGDAHLYRNHFEQAALQLEREPRALPVMKINPEVKDLFAFKFEDFELEGYDPHPH 258 Query: 70 IEMKMAV 50 I+ ++V Sbjct: 259 IKAVVSV 265
>TYSY_METFL (Q9RAM7) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 264 Score = 213 bits (543), Expect = 3e-55 Identities = 101/186 (54%), Positives = 133/186 (71%) Frame = -1 Query: 607 EGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTDL 428 EG+LGPVYG+QWR++ G DQ+++VI IK+NPD RR+I+SAWN D+ Sbjct: 87 EGNLGPVYGYQWRNWPKP--------DGGHIDQISEVIAAIKSNPDSRRLIVSAWNVADV 138 Query: 427 KKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPGE 248 KM LPPCH QFYV G+LSCQ+YQRSAD+ LGVPFNIASY+LLT M+A+VCDL G+ Sbjct: 139 DKMELPPCHALFQFYVAEGKLSCQLYQRSADIFLGVPFNIASYALLTMMVARVCDLELGD 198 Query: 247 FVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQKI 68 FVH +GDAH+Y H++ ++EQL ++P P P+++INP KDI +F DF L Y H I Sbjct: 199 FVHTLGDAHIYLNHLEQVKEQLSREPYPLPVMRINPEVKDIFAFRFEDFTLENYQSHPAI 258 Query: 67 EMKMAV 50 + +AV Sbjct: 259 KAPVAV 264
>TYSY_BDEBA (Q6MID2) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 264 Score = 213 bits (542), Expect = 4e-55 Identities = 103/187 (55%), Positives = 136/187 (72%) Frame = -1 Query: 610 EEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTD 431 E G+LGPVYG QWR + E +D G+ DQ+ +V+ +IK NP+ RR+++ A+NP D Sbjct: 86 ENGNLGPVYGKQWRSW--ETAD------GRTIDQITNVVEQIKKNPNSRRMLVVAFNPGD 137 Query: 430 LKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPG 251 + KMALPPCH F QFYV NG+LSCQ+YQRSAD+ LGVPFNIASY+LLT MIAQVCDL G Sbjct: 138 VDKMALPPCHAFFQFYVANGKLSCQLYQRSADIFLGVPFNIASYALLTHMIAQVCDLEVG 197 Query: 250 EFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQK 71 +FVH +GDAH+Y H++ QL ++ +P P LK+NP KKD+ F D ++ YDPH Sbjct: 198 DFVHTLGDAHLYLNHLEQANLQLTREFRPLPQLKLNPAKKDLFDFTYEDIEIIGYDPHPA 257 Query: 70 IEMKMAV 50 I+ ++AV Sbjct: 258 IKAEVAV 264
>TYSY_BACHD (Q9K7B5) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 264 Score = 209 bits (532), Expect = 5e-54 Identities = 97/187 (51%), Positives = 132/187 (70%) Frame = -1 Query: 610 EEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTD 431 E G+LGPVYG QWR + GK DQ++ V+ IK+ PD RR+I+SAWN + Sbjct: 86 ENGELGPVYGKQWRSWEGA--------NGKTVDQISQVVEAIKHQPDSRRLIVSAWNAAE 137 Query: 430 LKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPG 251 ++ MAL PCH QFYV++G+LSCQ+YQRSAD+ LGVPFNIASY+LLT MIAQVCDL G Sbjct: 138 IEDMALAPCHCLFQFYVQDGKLSCQLYQRSADIFLGVPFNIASYALLTKMIAQVCDLEEG 197 Query: 250 EFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQK 71 EFVH GDAH+Y H++ ++ QL ++P+P P +++NP + + F DF+L YDPH Sbjct: 198 EFVHTFGDAHIYLNHIEQVKLQLTREPRPLPEMRLNPEVRSLFDFTFDDFELVGYDPHPH 257 Query: 70 IEMKMAV 50 I+ +++V Sbjct: 258 IKGEVSV 264
>DRTS_CRIFA (Q23695) Bifunctional dihydrofolate reductase-thymidylate synthase| (DHFR-TS) [Includes: Dihydrofolate reductase (EC 1.5.1.3); Thymidylate synthase (EC 2.1.1.45)] Length = 515 Score = 206 bits (525), Expect = 3e-53 Identities = 99/189 (52%), Positives = 135/189 (71%), Gaps = 2/189 (1%) Frame = -1 Query: 610 EEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTD 431 +E DLGPVYGFQWRHFGA+Y A+Y +G DQ+ ++ +K N DRR++++AWNP Sbjct: 330 KEMDLGPVYGFQWRHFGADYKGFDANYD-EGVDQIKTIVETLKTN--DRRLLVTAWNPCA 386 Query: 430 LKKMALPPCHMFAQFYV--ENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLS 257 L KMA+ PCH+ QFYV + ELSC +YQR DMGLGVPFNIASY+LLT +IA+ L Sbjct: 387 LHKMAVRPCHLLGQFYVNTQTKELSCMLYQRCCDMGLGVPFNIASYALLTILIAKATGLR 446 Query: 256 PGEFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPH 77 PGE VH +G AHVYS HV+AL+EQLQ+ P FP+L ++ ++ + ++D ++ Y P+ Sbjct: 447 PGELVHTLGTAHVYSNHVEALKEQLQRVPVAFPVLVFKKEREFLEDYESTDMEVVDYVPY 506 Query: 76 QKIEMKMAV 50 I+M+MAV Sbjct: 507 PPIKMEMAV 515
>TYSY_BACSK (Q5WDS1) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 264 Score = 206 bits (524), Expect = 4e-53 Identities = 95/187 (50%), Positives = 132/187 (70%) Frame = -1 Query: 610 EEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTD 431 E GDLGPVYG QWR + GK DQ+ +V+ +IK NP+ RR+I++AWN + Sbjct: 86 ENGDLGPVYGKQWRSWEGA--------NGKTVDQITEVVEQIKTNPNSRRLIVNAWNVAE 137 Query: 430 LKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPG 251 +++MAL PCH QFYV +G+LSCQ+YQRSAD+ LGVPFNI+SY+LLT M+AQVC L PG Sbjct: 138 IEEMALAPCHCLFQFYVNDGKLSCQLYQRSADIFLGVPFNISSYALLTMMMAQVCGLKPG 197 Query: 250 EFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQK 71 EF+H GDAH+Y+ H++ + QL ++PK P + INP D+ +F DF+L YDP+ Sbjct: 198 EFIHTFGDAHLYNNHIEQTKLQLTRKPKQLPTMHINPEVTDLFAFTYDDFELKHYDPYPH 257 Query: 70 IEMKMAV 50 I+ +++V Sbjct: 258 IKAEVSV 264
>TYSY_NITEU (Q82WU3) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 264 Score = 205 bits (522), Expect = 7e-53 Identities = 100/187 (53%), Positives = 126/187 (67%) Frame = -1 Query: 610 EEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTD 431 E GDLGP+YG QWR + A G DQ++ VI +IK PD RR+I+SAWN D Sbjct: 86 ENGDLGPIYGHQWRSWAAS--------DGTVIDQISQVIQQIKETPDSRRMIVSAWNVGD 137 Query: 430 LKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPG 251 L KM L PCH+ QFYV +G LSCQ+YQRSAD+ LGVPFNIASYSLLT MIAQ CDL PG Sbjct: 138 LDKMKLAPCHVLFQFYVADGRLSCQLYQRSADIFLGVPFNIASYSLLTLMIAQCCDLQPG 197 Query: 250 EFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQK 71 EFVH GDAH+Y H++ QL+++P+ P +++N ++I F DF L YDP+ Sbjct: 198 EFVHTFGDAHLYLNHLEQARLQLEREPRALPAMQLNSTVRNIFDFGYEDFTLHDYDPYPP 257 Query: 70 IEMKMAV 50 I+ +AV Sbjct: 258 IKAPVAV 264
>TYSY_BARHE (Q6G2S8) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 264 Score = 205 bits (522), Expect = 7e-53 Identities = 96/187 (51%), Positives = 130/187 (69%) Frame = -1 Query: 610 EEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTD 431 E+G+LGP+YG+QWR + A G+ DQ+++++ IK PD RR+I+SAWNP Sbjct: 86 EKGNLGPIYGYQWRSWPAP--------DGRHIDQISNLLMMIKKTPDSRRLIVSAWNPAS 137 Query: 430 LKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPG 251 +K+MALPPCH F QFYV +G+LSCQ+YQRSAD+ LG+PFNIASY+LLT MIAQV L G Sbjct: 138 IKEMALPPCHCFFQFYVADGKLSCQLYQRSADIFLGIPFNIASYALLTMMIAQVSGLKVG 197 Query: 250 EFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQK 71 +F+H +GDAH+YS H + + QL + P P ++INP D+ SF DF+L YD Sbjct: 198 DFIHTLGDAHLYSNHFEQAQHQLSRIPNALPFMRINPAVTDLFSFKFEDFELLNYDAQPH 257 Query: 70 IEMKMAV 50 I+ +AV Sbjct: 258 IKAPIAV 264
>TYSY_BACFR (Q64PV5) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 264 Score = 205 bits (522), Expect = 7e-53 Identities = 100/187 (53%), Positives = 129/187 (68%) Frame = -1 Query: 610 EEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTD 431 E GDLG +YG+QWR + Y G DQ+++ ++ IK+NPD RRII+SAWN D Sbjct: 86 ETGDLGHIYGYQWRSWPT--------YDGGFIDQISEAVDAIKHNPDSRRIIVSAWNVGD 137 Query: 430 LKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPG 251 L M LPPCH F QFYV NG LS Q+YQRSAD+ LGVPFNIASY+LL M+AQV L G Sbjct: 138 LDHMNLPPCHAFFQFYVANGRLSLQLYQRSADIFLGVPFNIASYALLLQMMAQVTGLQAG 197 Query: 250 EFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQK 71 +F+H +GDAH+Y H++ ++ QL ++P+P P +KINP K+I F DF+L YDPH Sbjct: 198 DFIHTLGDAHIYLNHLEQVKLQLSREPRPLPQMKINPDVKNIFDFQFKDFELVNYDPHPH 257 Query: 70 IEMKMAV 50 I K+AV Sbjct: 258 IAGKVAV 264
>TYSY_BRUSU (P67043) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 264 Score = 205 bits (521), Expect = 1e-52 Identities = 99/187 (52%), Positives = 127/187 (67%) Frame = -1 Query: 610 EEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTD 431 E GDLGPVYG+QWR + A G+ DQ+A+++ + NP RR+I+SAWNP Sbjct: 86 ENGDLGPVYGYQWRSWPAP--------DGRHIDQIANLLKMLHTNPQSRRLIVSAWNPAL 137 Query: 430 LKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPG 251 + +MALPPCH QFYV NG LSCQ+YQRSAD+ LGVPFNIASY+LLT MIAQV L PG Sbjct: 138 VDEMALPPCHCLFQFYVANGRLSCQLYQRSADIFLGVPFNIASYALLTMMIAQVTGLKPG 197 Query: 250 EFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQK 71 EF+H +GDAH+YS H + QL + PK P++ INP KD+ +F DF+L Y+ Sbjct: 198 EFIHTLGDAHIYSNHFEQARLQLTRTPKKLPVMHINPDVKDLFAFRFEDFRLDGYEADPT 257 Query: 70 IEMKMAV 50 I+ +AV Sbjct: 258 IKAPIAV 264
>TYSY_BRUME (P67042) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 264 Score = 205 bits (521), Expect = 1e-52 Identities = 99/187 (52%), Positives = 127/187 (67%) Frame = -1 Query: 610 EEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTD 431 E GDLGPVYG+QWR + A G+ DQ+A+++ + NP RR+I+SAWNP Sbjct: 86 ENGDLGPVYGYQWRSWPAP--------DGRHIDQIANLLKMLHTNPQSRRLIVSAWNPAL 137 Query: 430 LKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPG 251 + +MALPPCH QFYV NG LSCQ+YQRSAD+ LGVPFNIASY+LLT MIAQV L PG Sbjct: 138 VDEMALPPCHCLFQFYVANGRLSCQLYQRSADIFLGVPFNIASYALLTMMIAQVTGLKPG 197 Query: 250 EFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQK 71 EF+H +GDAH+YS H + QL + PK P++ INP KD+ +F DF+L Y+ Sbjct: 198 EFIHTLGDAHIYSNHFEQARLQLTRTPKKLPVMHINPDVKDLFAFRFEDFRLDGYEADPT 257 Query: 70 IEMKMAV 50 I+ +AV Sbjct: 258 IKAPIAV 264
>TYSY_ENTFA (Q834R3) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 315 Score = 204 bits (519), Expect = 2e-52 Identities = 99/185 (53%), Positives = 125/185 (67%) Frame = -1 Query: 604 GDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTDLK 425 G+LG +YG QWRH+ + G DQLA+VI IK NPD RR+I+SAWNP D+ Sbjct: 139 GELGNIYGAQWRHWETK--------DGSFIDQLANVIEMIKTNPDSRRLIVSAWNPEDVP 190 Query: 424 KMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPGEF 245 MALPPCH QFYV G+LSCQ+YQRSAD+ LGVPFNIASY+LLT +IA L GEF Sbjct: 191 SMALPPCHTMFQFYVNEGKLSCQLYQRSADVFLGVPFNIASYALLTHLIAHETGLEVGEF 250 Query: 244 VHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQKIE 65 VH +GDAH+Y HV+ ++EQL ++ + FP L +NP K + F D K+ YDPH I+ Sbjct: 251 VHTLGDAHLYQNHVEQMQEQLSREVRSFPTLVLNPDKASVFDFDMEDIKVEGYDPHPTIK 310 Query: 64 MKMAV 50 +AV Sbjct: 311 APIAV 315
>TYSY_RHILO (Q98KH9) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 264 Score = 204 bits (519), Expect = 2e-52 Identities = 100/187 (53%), Positives = 127/187 (67%) Frame = -1 Query: 610 EEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTD 431 E GDLGPVYG QWR + D H G DQ+A ++ +I+ NP RR+I+SAWNP + Sbjct: 86 ENGDLGPVYGRQWR----SWPDGH----GGSIDQIAGLLKEIRRNPQSRRLIVSAWNPAE 137 Query: 430 LKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPG 251 ++ MALPPCH QFYV G LSCQ+YQRSAD+ LGVPFNIASY+LLT M+AQV L PG Sbjct: 138 VEAMALPPCHCLFQFYVSEGRLSCQLYQRSADIFLGVPFNIASYALLTLMVAQVTGLKPG 197 Query: 250 EFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQK 71 +FVH +GDAH+YS H + EQLQ+ P+ P + INP KD+ +F DF+L Y Sbjct: 198 DFVHTLGDAHLYSNHFEQAREQLQRTPRALPTMWINPEVKDLFAFRFEDFRLENYVADAS 257 Query: 70 IEMKMAV 50 I+ +AV Sbjct: 258 IQAPIAV 264
>TYSY_PSEAE (Q9I6F1) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 264 Score = 204 bits (519), Expect = 2e-52 Identities = 97/187 (51%), Positives = 130/187 (69%) Frame = -1 Query: 610 EEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTD 431 E GDLGPVYG+QWR + A G+ DQ+A+++ +K NPD RR+I+SAWNP Sbjct: 86 ENGDLGPVYGYQWRSWPAP--------DGRHIDQIANLMAMLKKNPDSRRLIVSAWNPAL 137 Query: 430 LKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPG 251 + +MALPPCH QFYV +G+LSCQ+YQRSAD+ LGVPFNIASY+LLT M+AQV L PG Sbjct: 138 IDEMALPPCHALFQFYVADGKLSCQLYQRSADIFLGVPFNIASYALLTLMVAQVAGLQPG 197 Query: 250 EFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQK 71 EF+ GD H+Y+ H++ + QL ++P P P +K+NP KD+ F DF+L Y+ H Sbjct: 198 EFIWTGGDCHLYANHLEQADLQLTREPLPLPSMKLNPEVKDLFDFRFEDFELVGYEAHPH 257 Query: 70 IEMKMAV 50 I+ +AV Sbjct: 258 IKAPVAV 264
>TYSY_BACTN (Q8A639) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 264 Score = 203 bits (517), Expect = 3e-52 Identities = 100/187 (53%), Positives = 126/187 (67%) Frame = -1 Query: 610 EEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTD 431 E GDLG +YG+QWR + DY G DQ+++ + IK+NPD RRII+SAWN D Sbjct: 86 ENGDLGHIYGYQWRSW--------PDYDGGFIDQISEAVETIKHNPDSRRIIVSAWNVAD 137 Query: 430 LKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPG 251 LK M LPPCH F QFYV +G LS Q+YQRSAD+ LGVPFNIASY+LL M+AQV L G Sbjct: 138 LKNMNLPPCHAFFQFYVADGRLSLQLYQRSADIFLGVPFNIASYALLLQMMAQVTGLKAG 197 Query: 250 EFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQK 71 EF+H +GDAH+Y H+ ++ QL ++P+ P +KINP K I F DF+L YDPH Sbjct: 198 EFIHTLGDAHIYLNHLDQVKLQLSREPRALPQMKINPDVKSIYDFQFEDFELVNYDPHPH 257 Query: 70 IEMKMAV 50 I +AV Sbjct: 258 IAGIVAV 264
>TYSY_BACHK (Q6HJC7) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 318 Score = 203 bits (516), Expect = 4e-52 Identities = 99/185 (53%), Positives = 123/185 (66%) Frame = -1 Query: 604 GDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTDLK 425 G LG VYG QWR + G+ DQL DVI IK PD RR+I+SAWNP D+ Sbjct: 142 GYLGDVYGKQWRAWKTT--------AGETLDQLKDVIEMIKKTPDSRRLIVSAWNPEDVP 193 Query: 424 KMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPGEF 245 MALPPCH QFYV +G+LSCQ+YQRS D+ LG+PFNIASYSLLT +IA C L GEF Sbjct: 194 SMALPPCHTLFQFYVADGKLSCQLYQRSGDIFLGIPFNIASYSLLTHLIAHECGLEVGEF 253 Query: 244 VHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQKIE 65 VH IGDAH+Y+ H + +E+QL ++P+PFP L +NP K + F D + YDPH I+ Sbjct: 254 VHTIGDAHIYTNHFEQVEKQLAREPRPFPKLTLNPDVKSVFDFEMEDLTIEGYDPHPAIK 313 Query: 64 MKMAV 50 +AV Sbjct: 314 APVAV 318
>TYSY_BACCZ (Q63BV5) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 318 Score = 203 bits (516), Expect = 4e-52 Identities = 99/185 (53%), Positives = 123/185 (66%) Frame = -1 Query: 604 GDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTDLK 425 G LG VYG QWR + G+ DQL DVI IK PD RR+I+SAWNP D+ Sbjct: 142 GYLGDVYGKQWRAWKTT--------AGETLDQLKDVIEMIKKTPDSRRLIVSAWNPEDVP 193 Query: 424 KMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPGEF 245 MALPPCH QFYV +G+LSCQ+YQRS D+ LG+PFNIASYSLLT +IA C L GEF Sbjct: 194 SMALPPCHTLFQFYVADGKLSCQLYQRSGDIFLGIPFNIASYSLLTHLIAHECGLEVGEF 253 Query: 244 VHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQKIE 65 VH IGDAH+Y+ H + +E+QL ++P+PFP L +NP K + F D + YDPH I+ Sbjct: 254 VHTIGDAHIYTNHFEQVEKQLAREPRPFPKLTLNPDVKSVFDFEMEDLTIEGYDPHPAIK 313 Query: 64 MKMAV 50 +AV Sbjct: 314 APVAV 318
>TYSY_BACCR (Q81E05) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 318 Score = 203 bits (516), Expect = 4e-52 Identities = 99/185 (53%), Positives = 123/185 (66%) Frame = -1 Query: 604 GDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTDLK 425 G LG VYG QWR + G+ DQL DVI IK PD RR+I+SAWNP D+ Sbjct: 142 GYLGDVYGKQWRAWKTT--------AGETLDQLKDVIEMIKKTPDSRRLIVSAWNPEDVP 193 Query: 424 KMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPGEF 245 MALPPCH QFYV +G+LSCQ+YQRS D+ LG+PFNIASYSLLT +IA C L GEF Sbjct: 194 SMALPPCHTLFQFYVADGKLSCQLYQRSGDIFLGIPFNIASYSLLTHLIAHECGLEVGEF 253 Query: 244 VHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQKIE 65 VH IGDAH+Y+ H + +E+QL ++P+PFP L +NP K + F D + YDPH I+ Sbjct: 254 VHTIGDAHIYTNHFEQVEKQLAREPRPFPKLTLNPDVKSVFDFEMEDLTIEGYDPHPAIK 313 Query: 64 MKMAV 50 +AV Sbjct: 314 APVAV 318
>TYSY_BACC1 (Q738X7) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 318 Score = 203 bits (516), Expect = 4e-52 Identities = 99/185 (53%), Positives = 123/185 (66%) Frame = -1 Query: 604 GDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTDLK 425 G LG VYG QWR + G+ DQL DVI IK PD RR+I+SAWNP D+ Sbjct: 142 GYLGDVYGKQWRAWKTT--------AGETLDQLKDVIEMIKKTPDSRRLIVSAWNPEDVP 193 Query: 424 KMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPGEF 245 MALPPCH QFYV +G+LSCQ+YQRS D+ LG+PFNIASYSLLT +IA C L GEF Sbjct: 194 SMALPPCHTLFQFYVADGKLSCQLYQRSGDIFLGIPFNIASYSLLTHLIAHECGLEVGEF 253 Query: 244 VHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQKIE 65 VH IGDAH+Y+ H + +E+QL ++P+PFP L +NP K + F D + YDPH I+ Sbjct: 254 VHTIGDAHIYTNHFEQVEKQLAREPRPFPKLTLNPDVKSVFDFEMEDLTIEGYDPHPAIK 313 Query: 64 MKMAV 50 +AV Sbjct: 314 APVAV 318
>TYSY_BACAN (Q81R23) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 318 Score = 203 bits (516), Expect = 4e-52 Identities = 99/185 (53%), Positives = 123/185 (66%) Frame = -1 Query: 604 GDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTDLK 425 G LG VYG QWR + G+ DQL DVI IK PD RR+I+SAWNP D+ Sbjct: 142 GYLGDVYGKQWRAWKTT--------AGETLDQLKDVIEMIKKTPDSRRLIVSAWNPEDVP 193 Query: 424 KMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPGEF 245 MALPPCH QFYV +G+LSCQ+YQRS D+ LG+PFNIASYSLLT +IA C L GEF Sbjct: 194 SMALPPCHTLFQFYVADGKLSCQLYQRSGDIFLGIPFNIASYSLLTHLIAHECGLEVGEF 253 Query: 244 VHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQKIE 65 VH IGDAH+Y+ H + +E+QL ++P+PFP L +NP K + F D + YDPH I+ Sbjct: 254 VHTIGDAHIYTNHFEQVEKQLAREPRPFPKLTLNPDVKSVFDFEMEDLTIEGYDPHPAIK 313 Query: 64 MKMAV 50 +AV Sbjct: 314 APVAV 318
>TYSY_ACIAD (Q6FER7) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 280 Score = 201 bits (511), Expect = 1e-51 Identities = 97/188 (51%), Positives = 129/188 (68%) Frame = -1 Query: 613 REEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPT 434 R EG+LGPVYG QWR+FGA + Y GFDQ+ +IN+IK NP+ RR+I+S WNP Sbjct: 94 RPEGELGPVYGHQWRNFGATQNS-DGSYKNDGFDQIKWLINEIKTNPNSRRLIVSGWNPN 152 Query: 433 DLKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSP 254 + ++ALPPCH QF+V++G+LSCQ+YQRSAD+ LGVPFNIASY+LLT MIAQVC L Sbjct: 153 EAGQVALPPCHTLFQFFVQDGKLSCQLYQRSADVFLGVPFNIASYALLTHMIAQVCGLGV 212 Query: 253 GEFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQ 74 G+FV GD H+Y+ H + + QL ++P P LK+NP D+ F D ++ Y H Sbjct: 213 GDFVWTGGDTHLYANHFEQAQLQLTREPLPLCQLKLNPEITDLFDFKFEDIEIVDYQSHP 272 Query: 73 KIEMKMAV 50 I+ +AV Sbjct: 273 AIKAPVAV 280
>TYSY_RHIME (Q92NQ5) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 264 Score = 200 bits (508), Expect = 3e-51 Identities = 97/187 (51%), Positives = 127/187 (67%) Frame = -1 Query: 610 EEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTD 431 E G+LGPVYG+QWR + G+ DQ+A ++ +K NP+ RR I+SAWNP Sbjct: 86 ENGELGPVYGYQWRSWPTP--------DGRHIDQIAALVEGLKTNPNSRRHIVSAWNPAL 137 Query: 430 LKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPG 251 + +MALPPCH QFYV +G+LSCQ+YQRSAD+ LGVPFNIASY+LLT M+AQV L G Sbjct: 138 VDEMALPPCHCLFQFYVADGKLSCQLYQRSADIFLGVPFNIASYALLTMMVAQVTGLEAG 197 Query: 250 EFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQK 71 +FVH +GDAH+Y H + + QL + PKP P ++INP KDI SF DF+L Y+ Sbjct: 198 DFVHTLGDAHIYRNHFEQAQLQLTRTPKPLPKMEINPAVKDIFSFRFEDFELVGYEADSH 257 Query: 70 IEMKMAV 50 I+ +AV Sbjct: 258 IKAPVAV 264
>TYSY_LACCA (P00469) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 316 Score = 199 bits (506), Expect = 5e-51 Identities = 101/187 (54%), Positives = 126/187 (67%), Gaps = 2/187 (1%) Frame = -1 Query: 604 GDLGPVYGFQWRHFGAEYSDMHADYTGKG--FDQLADVINKIKNNPDDRRIILSAWNPTD 431 GDLG VYG QWR A +T KG DQL DVI +IK +P RR+I+SAWNP D Sbjct: 140 GDLGLVYGSQWR----------AWHTSKGDTIDQLGDVIEQIKTHPYSRRLIVSAWNPED 189 Query: 430 LKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPG 251 + MALPPCH QFYV +G+LS Q+YQRSAD+ LGVPFNIASY+LLT ++A C L G Sbjct: 190 VPTMALPPCHTLYQFYVNDGKLSLQLYQRSADIFLGVPFNIASYALLTHLVAHECGLEVG 249 Query: 250 EFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQK 71 EF+H GDAH+Y H+ ++EQL + P+P P L++NP K DI F D KL YDP+ Sbjct: 250 EFIHTFGDAHLYVNHLDQIKEQLSRTPRPAPTLQLNPDKHDIFDFDMKDIKLLNYDPYPA 309 Query: 70 IEMKMAV 50 I+ +AV Sbjct: 310 IKAPVAV 316
>TYSY_RHOBA (Q7UID0) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 264 Score = 199 bits (505), Expect = 7e-51 Identities = 97/187 (51%), Positives = 119/187 (63%) Frame = -1 Query: 610 EEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTD 431 E GDLGPVYG QWR + D DQ+A V N+I+ NP RR+++SAWN D Sbjct: 86 EAGDLGPVYGHQWRSWEGANGDT--------VDQIAWVENEIRTNPRSRRLVVSAWNVAD 137 Query: 430 LKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPG 251 + KMALPPCH+ QFYV G LSCQ+YQRSAD+ LGVPFNIASY++LT M+A V L PG Sbjct: 138 VPKMALPPCHLLFQFYVSGGRLSCQLYQRSADLFLGVPFNIASYAMLTSMMAHVTGLKPG 197 Query: 250 EFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQK 71 EFVH +GD H+YS H EQL + P+P P I + F DF+L YDPH Sbjct: 198 EFVHTLGDVHLYSNHFDQAREQLSRTPRPLPTFHIKRDVASVTDFQFDDFELTNYDPHPH 257 Query: 70 IEMKMAV 50 I+ +AV Sbjct: 258 IKAPVAV 264
>TYSY_LACPL (Q88W05) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 316 Score = 197 bits (501), Expect = 2e-50 Identities = 96/185 (51%), Positives = 127/185 (68%) Frame = -1 Query: 604 GDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTDLK 425 G+LG VYG QWRH+ GK DQ+A+VI IK +PD RR+I+SAWNP D+ Sbjct: 140 GNLGDVYGAQWRHWQTRQ--------GKTIDQIANVIEMIKTHPDSRRLIVSAWNPEDVP 191 Query: 424 KMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPGEF 245 MALPPCH QFYV +G+LSCQ+YQRS D+ LGVPFNIASY+LLT +IA+ L+ GEF Sbjct: 192 NMALPPCHTLFQFYVADGKLSCQLYQRSGDVFLGVPFNIASYALLTHLIAKETGLAVGEF 251 Query: 244 VHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQKIE 65 VH +GDAH+Y+ HV+ ++ QL +QP+P P L ++ I + SD KL+ YDP I+ Sbjct: 252 VHTLGDAHIYTNHVEQVKTQLTRQPRPAPQLTLSGAHDSIFDYQMSDIKLSGYDPAPAIK 311 Query: 64 MKMAV 50 +A+ Sbjct: 312 APVAI 316
>TYSY_XYLFA (Q9PB13) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 264 Score = 197 bits (500), Expect = 3e-50 Identities = 95/185 (51%), Positives = 126/185 (68%) Frame = -1 Query: 604 GDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTDLK 425 G+LGPVYG QWR + A G DQ+ ++ +IK NPD RR+++SAWN DL Sbjct: 88 GELGPVYGKQWRRW--------AGADGHEIDQIRWLLEEIKRNPDSRRLVISAWNVADLP 139 Query: 424 KMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPGEF 245 +MAL PCH QFYV NG+LSCQ+YQRSAD+ LGVPFNIASY+LLT M+AQV L+ G+F Sbjct: 140 QMALVPCHALFQFYVANGKLSCQLYQRSADIFLGVPFNIASYALLTHMLAQVTGLAVGDF 199 Query: 244 VHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQKIE 65 VH +GDAH+Y+ HV+ QL++ P+P P+L +NP D+ F D + YDP+ I+ Sbjct: 200 VHTLGDAHLYANHVEQASVQLERVPRPQPVLMLNPAVTDLFDFTYDDIVIEGYDPYPAIK 259 Query: 64 MKMAV 50 +AV Sbjct: 260 APVAV 264
>TYSY_AGRT5 (Q8UDS3) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 264 Score = 196 bits (498), Expect = 4e-50 Identities = 95/187 (50%), Positives = 126/187 (67%) Frame = -1 Query: 610 EEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTD 431 E GDLGPVYG QWR + A G+ DQ+A +I +K NP+ RR I+SAWNP Sbjct: 86 ENGDLGPVYGAQWRSWPAP--------DGRHIDQIALLIEALKTNPNSRRHIVSAWNPAL 137 Query: 430 LKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPG 251 + +MALPPCH QFYV +G+LSCQ+YQRSAD+ LGVPFNIASY+LLT M+AQV L PG Sbjct: 138 VDEMALPPCHCLFQFYVSDGKLSCQLYQRSADIFLGVPFNIASYALLTLMVAQVVGLKPG 197 Query: 250 EFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQK 71 +FVH +GDAH+Y+ H + + Q+ + PK P +++NP K++ F DF L Y+ Sbjct: 198 DFVHTLGDAHIYANHFEQAQLQMTRTPKALPTMRLNPDVKNLFGFKFEDFTLENYEADSS 257 Query: 70 IEMKMAV 50 I+ +AV Sbjct: 258 IKAPIAV 264
>TYSY_OCEIH (Q8EQG0) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 317 Score = 196 bits (497), Expect = 6e-50 Identities = 98/185 (52%), Positives = 123/185 (66%) Frame = -1 Query: 604 GDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTDLK 425 GDLG VYG QWR++ ++ DQL DVI+ IK NP+ RR I+SAWNP D+ Sbjct: 141 GDLGSVYGKQWRNWKTTQNET--------IDQLKDVIHSIKTNPNSRRHIVSAWNPEDIP 192 Query: 424 KMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPGEF 245 MALPPCH QFYV NG+LSCQ+YQRSAD+ LGVPFNIASY+LLT +IA C L G+F Sbjct: 193 TMALPPCHTLFQFYVSNGKLSCQLYQRSADVFLGVPFNIASYALLTHLIAHECGLEVGDF 252 Query: 244 VHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQKIE 65 VH GDAH+YS HV+ +E QL+++ + FP L IN K I D + Y+PH I+ Sbjct: 253 VHTFGDAHIYSNHVEQVETQLEREIRDFPQLIINKDKNSIFEMDLDDLVIENYNPHPSIK 312 Query: 64 MKMAV 50 +AV Sbjct: 313 APIAV 317
>TYSY_MYCMO (Q6KIQ6) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 288 Score = 194 bits (493), Expect = 2e-49 Identities = 95/188 (50%), Positives = 122/188 (64%) Frame = -1 Query: 613 REEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPT 434 ++ G+LGPVYG QWR+F G DQL D I IK NPD RRII+SAW Sbjct: 114 KKYGELGPVYGKQWRNFN-------------GTDQLFDAIETIKKNPDSRRIIVSAWAAN 160 Query: 433 DLKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSP 254 ++ KMALPPCH F QFYV N +LS Q+YQRS D LGVPFNIASYS+L M+AQ+ + Sbjct: 161 EISKMALPPCHAFFQFYVNNNKLSLQLYQRSGDTFLGVPFNIASYSILLAMVAQITNYEV 220 Query: 253 GEFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQ 74 GEF+H IGD H+Y H++ +EEQL ++P P L +N K+ID F D ++ Y+ H Sbjct: 221 GEFIHTIGDTHIYLNHLEQVEEQLSRKPLKLPKLVLNKKIKNIDDFKYEDIEIIDYESHP 280 Query: 73 KIEMKMAV 50 I+ K+AV Sbjct: 281 AIKAKVAV 288
>TYSY_SHEON (Q8EH94) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 264 Score = 194 bits (493), Expect = 2e-49 Identities = 95/187 (50%), Positives = 126/187 (67%) Frame = -1 Query: 610 EEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTD 431 E GDLGPVYG QWR + + +G+ DQ++ VI +IK+ PD RR+I+SAWN + Sbjct: 86 ENGDLGPVYGAQWRSWPTQ--------SGEAIDQISQVIAQIKSQPDSRRLIVSAWNVGE 137 Query: 430 LKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPG 251 L KMAL PCH F QFYV +G+LSCQ+YQRS D+ LG+PFNIASY+LLT M+AQ CDL+ G Sbjct: 138 LDKMALAPCHAFFQFYVADGKLSCQLYQRSCDVFLGLPFNIASYALLTMMVAQQCDLALG 197 Query: 250 EFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQK 71 +FV GD H+YS H++ QL ++P+P P + I I + DF L+ YDPH Sbjct: 198 DFVWTGGDTHLYSNHMEQTALQLSREPRPLPTMTILRKPASIFDYQFDDFALSNYDPHPH 257 Query: 70 IEMKMAV 50 I+ +AV Sbjct: 258 IKAPVAV 264
>TYSY_BARQU (Q6FZ91) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 264 Score = 194 bits (493), Expect = 2e-49 Identities = 94/187 (50%), Positives = 126/187 (67%) Frame = -1 Query: 610 EEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTD 431 E+G+LGP+YG+QWR + A G+ DQ++ ++ IK PD RR+I+SAWNP Sbjct: 86 EKGNLGPIYGYQWRSWPAS--------DGRYIDQISRLLTMIKKTPDSRRLIVSAWNPAL 137 Query: 430 LKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPG 251 +++MALPPCH F QFYV + +LSCQ+YQRSAD+ LGVPFNIASY+LLT MIAQV L G Sbjct: 138 IEEMALPPCHCFFQFYVADDKLSCQLYQRSADIFLGVPFNIASYALLTMMIAQVSGLKAG 197 Query: 250 EFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQK 71 +F+H +GDAH+YS H + QL + P P + INP D+ SF DF+L Y+ Sbjct: 198 DFIHTLGDAHLYSNHFEQARYQLSRIPNALPSMLINPSVTDLFSFKFEDFELLNYEAQPH 257 Query: 70 IEMKMAV 50 I+ +AV Sbjct: 258 IKAPVAV 264
>TYSY_STAAW (P67048) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 318 Score = 193 bits (491), Expect = 3e-49 Identities = 99/188 (52%), Positives = 126/188 (67%) Frame = -1 Query: 613 REEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPT 434 ++ GDLG VYG QWR + D G FDQL VI +IK+NPD RR I+SAWNPT Sbjct: 140 KQFGDLGNVYGKQWRDW--------VDKDGNHFDQLKTVIEQIKHNPDSRRHIVSAWNPT 191 Query: 433 DLKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSP 254 ++ MALPPCH QFYV++G+LSCQ+YQRSAD+ LGVPFNIASY+LLT +IA+ C L Sbjct: 192 EIDTMALPPCHTMFQFYVQDGKLSCQLYQRSADIFLGVPFNIASYALLTHLIAKECGLEV 251 Query: 253 GEFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQ 74 GEFVH GDAH+YS H+ A++ QL ++ P LKIN K I D ++ Y+ H Sbjct: 252 GEFVHTFGDAHIYSNHIDAIQTQLARESFNPPTLKINS-DKSIFDINYEDLEIVDYESHP 310 Query: 73 KIEMKMAV 50 I+ +AV Sbjct: 311 AIKAPIAV 318
>TYSY_STAAS (Q6G9D4) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 318 Score = 193 bits (491), Expect = 3e-49 Identities = 99/188 (52%), Positives = 126/188 (67%) Frame = -1 Query: 613 REEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPT 434 ++ GDLG VYG QWR + D G FDQL VI +IK+NPD RR I+SAWNPT Sbjct: 140 KQFGDLGNVYGKQWRDW--------VDKDGNHFDQLKTVIEQIKHNPDSRRHIVSAWNPT 191 Query: 433 DLKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSP 254 ++ MALPPCH QFYV++G+LSCQ+YQRSAD+ LGVPFNIASY+LLT +IA+ C L Sbjct: 192 EIDTMALPPCHTMFQFYVQDGKLSCQLYQRSADIFLGVPFNIASYALLTHLIAKECGLEV 251 Query: 253 GEFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQ 74 GEFVH GDAH+YS H+ A++ QL ++ P LKIN K I D ++ Y+ H Sbjct: 252 GEFVHTFGDAHIYSNHIDAIQTQLARESFNPPTLKINS-DKSIFDINYEDLEIVDYESHP 310 Query: 73 KIEMKMAV 50 I+ +AV Sbjct: 311 AIKAPIAV 318
>TYSY_STAAR (Q6GGY0) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 318 Score = 193 bits (491), Expect = 3e-49 Identities = 99/188 (52%), Positives = 126/188 (67%) Frame = -1 Query: 613 REEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPT 434 ++ GDLG VYG QWR + D G FDQL VI +IK+NPD RR I+SAWNPT Sbjct: 140 KQFGDLGNVYGKQWRDW--------VDKDGNHFDQLKTVIEQIKHNPDSRRHIVSAWNPT 191 Query: 433 DLKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSP 254 ++ MALPPCH QFYV++G+LSCQ+YQRSAD+ LGVPFNIASY+LLT +IA+ C L Sbjct: 192 EIDTMALPPCHTMFQFYVQDGKLSCQLYQRSADIFLGVPFNIASYALLTHLIAKECGLEV 251 Query: 253 GEFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQ 74 GEFVH GDAH+YS H+ A++ QL ++ P LKIN K I D ++ Y+ H Sbjct: 252 GEFVHTFGDAHIYSNHIDAIQTQLARESFNPPTLKINS-DKSIFDINYEDLEIVDYESHP 310 Query: 73 KIEMKMAV 50 I+ +AV Sbjct: 311 AIKAPIAV 318
>TYSY_STAAN (P67047) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 318 Score = 193 bits (491), Expect = 3e-49 Identities = 99/188 (52%), Positives = 126/188 (67%) Frame = -1 Query: 613 REEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPT 434 ++ GDLG VYG QWR + D G FDQL VI +IK+NPD RR I+SAWNPT Sbjct: 140 KQFGDLGNVYGKQWRDW--------VDKDGNHFDQLKTVIEQIKHNPDSRRHIVSAWNPT 191 Query: 433 DLKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSP 254 ++ MALPPCH QFYV++G+LSCQ+YQRSAD+ LGVPFNIASY+LLT +IA+ C L Sbjct: 192 EIDTMALPPCHTMFQFYVQDGKLSCQLYQRSADIFLGVPFNIASYALLTHLIAKECGLEV 251 Query: 253 GEFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQ 74 GEFVH GDAH+YS H+ A++ QL ++ P LKIN K I D ++ Y+ H Sbjct: 252 GEFVHTFGDAHIYSNHIDAIQTQLARESFNPPTLKINS-DKSIFDINYEDLEIVDYESHP 310 Query: 73 KIEMKMAV 50 I+ +AV Sbjct: 311 AIKAPIAV 318
>TYSY_STAAM (P67046) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 318 Score = 193 bits (491), Expect = 3e-49 Identities = 99/188 (52%), Positives = 126/188 (67%) Frame = -1 Query: 613 REEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPT 434 ++ GDLG VYG QWR + D G FDQL VI +IK+NPD RR I+SAWNPT Sbjct: 140 KQFGDLGNVYGKQWRDW--------VDKDGNHFDQLKTVIEQIKHNPDSRRHIVSAWNPT 191 Query: 433 DLKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSP 254 ++ MALPPCH QFYV++G+LSCQ+YQRSAD+ LGVPFNIASY+LLT +IA+ C L Sbjct: 192 EIDTMALPPCHTMFQFYVQDGKLSCQLYQRSADIFLGVPFNIASYALLTHLIAKECGLEV 251 Query: 253 GEFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQ 74 GEFVH GDAH+YS H+ A++ QL ++ P LKIN K I D ++ Y+ H Sbjct: 252 GEFVHTFGDAHIYSNHIDAIQTQLARESFNPPTLKINS-DKSIFDINYEDLEIVDYESHP 310 Query: 73 KIEMKMAV 50 I+ +AV Sbjct: 311 AIKAPIAV 318
>TYSY_STAAC (Q5HFZ6) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 318 Score = 193 bits (491), Expect = 3e-49 Identities = 99/188 (52%), Positives = 126/188 (67%) Frame = -1 Query: 613 REEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPT 434 ++ GDLG VYG QWR + D G FDQL VI +IK+NPD RR I+SAWNPT Sbjct: 140 KQFGDLGNVYGKQWRDW--------VDKDGNHFDQLKTVIEQIKHNPDSRRHIVSAWNPT 191 Query: 433 DLKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSP 254 ++ MALPPCH QFYV++G+LSCQ+YQRSAD+ LGVPFNIASY+LLT +IA+ C L Sbjct: 192 EIDTMALPPCHTMFQFYVQDGKLSCQLYQRSADIFLGVPFNIASYALLTHLIAKECGLEV 251 Query: 253 GEFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQ 74 GEFVH GDAH+YS H+ A++ QL ++ P LKIN K I D ++ Y+ H Sbjct: 252 GEFVHTFGDAHIYSNHIDAIQTQLARESFNPPTLKINS-DKSIFDINYEDLEIVDYESHP 310 Query: 73 KIEMKMAV 50 I+ +AV Sbjct: 311 AIKAPIAV 318
>TYSY_XYLFT (Q87BT4) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 264 Score = 192 bits (489), Expect = 5e-49 Identities = 94/185 (50%), Positives = 124/185 (67%) Frame = -1 Query: 604 GDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTDLK 425 G+LGPVYG QWR + A G DQ+ ++ +IK NPD RR+++SAWN DL Sbjct: 88 GELGPVYGKQWRRW--------AGADGHEIDQIRWLVEEIKRNPDSRRLVISAWNVADLP 139 Query: 424 KMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPGEF 245 +MAL PCH QFYV NG+LSCQ+YQRSAD+ LGVPFNIASY+LLT M+AQV L G+F Sbjct: 140 QMALVPCHALFQFYVANGKLSCQLYQRSADIFLGVPFNIASYALLTHMLAQVTGLVVGDF 199 Query: 244 VHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQKIE 65 VH +GDAH+Y+ HV+ QL + P+P P+L++N D+ F D + YDP+ I+ Sbjct: 200 VHTLGDAHLYANHVEQASVQLGRVPRPQPVLRLNQAVTDLFDFTYDDIVIEGYDPYPAIK 259 Query: 64 MKMAV 50 +AV Sbjct: 260 APVAV 264
>TYSY_PORGI (Q7MTB5) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 264 Score = 192 bits (489), Expect = 5e-49 Identities = 92/187 (49%), Positives = 121/187 (64%) Frame = -1 Query: 610 EEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTD 431 E GDLGP+YG+QWR + DY G DQ+ +V+ +++ PD RRII+ +WN Sbjct: 86 ENGDLGPIYGYQWRSW--------PDYRGGHIDQMQEVLRQLREEPDSRRIIVCSWNVGQ 137 Query: 430 LKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPG 251 L M LPPCH F QFYV +G LS Q+YQRSAD LG+PFNIASY+LL MIA V L PG Sbjct: 138 LADMHLPPCHCFMQFYVADGRLSLQLYQRSADSFLGIPFNIASYALLLQMIAHVTGLKPG 197 Query: 250 EFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQK 71 FVH +GDAH+Y H++ ++ QL ++P+ P + +NP D+ F DF+L YDPH Sbjct: 198 RFVHTLGDAHIYLNHLEQVQLQLSREPRALPRMVLNPEVSDLFDFRYEDFRLEGYDPHPH 257 Query: 70 IEMKMAV 50 I +AV Sbjct: 258 IAGVVAV 264
>TYSY_AZOSE (Q5P233) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 264 Score = 192 bits (489), Expect = 5e-49 Identities = 96/187 (51%), Positives = 121/187 (64%) Frame = -1 Query: 610 EEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTD 431 E GDLGPVYG QWR + G DQ+A +I+ +K+NPD RR ++SAWNP + Sbjct: 86 ENGDLGPVYGKQWRRWETA--------NGATIDQIAQLIDGLKHNPDSRRHLVSAWNPGE 137 Query: 430 LKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPG 251 + MALPPCH QFYV LSCQ+YQRSAD+ LGVPFNIASY+LLT M+AQVC L G Sbjct: 138 VAGMALPPCHALFQFYVAGDRLSCQLYQRSADIFLGVPFNIASYALLTLMVAQVCGLRAG 197 Query: 250 EFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQK 71 +FV GD H+Y H+ QL +QP+ P + +NP DI F DF+L YDPH Sbjct: 198 DFVWTGGDCHLYLNHLDQARLQLSRQPRALPRMIVNPGVTDIFGFRFEDFRLEGYDPHPH 257 Query: 70 IEMKMAV 50 I+ ++AV Sbjct: 258 IKAEVAV 264
>TYSY_CAUCR (Q9A6H0) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 279 Score = 192 bits (487), Expect = 8e-49 Identities = 95/187 (50%), Positives = 125/187 (66%) Frame = -1 Query: 610 EEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTD 431 E GDLGPVYG QWR + A G+ DQ++ ++ +K NP+ RR I++AWNP D Sbjct: 102 ENGDLGPVYGKQWRSW--------ATPDGRVIDQISALVENLKANPNSRRHIVTAWNPAD 153 Query: 430 LKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPG 251 + MALPPCH QF+V +G+LSCQ+YQRSAD+ LGVPFNIASY+LLT M+A+V L PG Sbjct: 154 VDDMALPPCHCLFQFFVADGKLSCQLYQRSADVFLGVPFNIASYALLTLMVAKVVGLEPG 213 Query: 250 EFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQK 71 EFVH GDAH+Y H+ EQL ++P FP +KI K+D+ F DF L Y H Sbjct: 214 EFVHTFGDAHLYLNHLDQAREQLTREPFDFPTMKIAD-KRDLFGFEYEDFTLEGYQAHPH 272 Query: 70 IEMKMAV 50 I+ +++V Sbjct: 273 IKAEVSV 279
>TYSY_XANCP (Q8PCE7) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 264 Score = 192 bits (487), Expect = 8e-49 Identities = 93/185 (50%), Positives = 123/185 (66%) Frame = -1 Query: 604 GDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTDLK 425 GDLGPVYG QWR + G DQ+ ++++IK NPD RR+++SAWN +L Sbjct: 88 GDLGPVYGKQWRRWTGP--------DGVEIDQMQWLVDEIKRNPDSRRLVISAWNVGELP 139 Query: 424 KMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPGEF 245 +MAL PCH QFYV +G+LSCQ+YQRS D+ LGVPFNIASY+LLT M+AQ L G+F Sbjct: 140 QMALMPCHSLFQFYVVDGKLSCQLYQRSGDIFLGVPFNIASYALLTHMVAQATGLGVGDF 199 Query: 244 VHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQKIE 65 VH +GDAH+YS H + EQL + P+P P L++NP D+ +F D + YDPH I+ Sbjct: 200 VHTLGDAHLYSNHFEQAREQLTRTPRPLPTLRLNPDVTDLFAFRFEDIAIDGYDPHPAIK 259 Query: 64 MKMAV 50 +AV Sbjct: 260 APVAV 264
>TYSY_XANAC (Q8PP46) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 264 Score = 192 bits (487), Expect = 8e-49 Identities = 93/187 (49%), Positives = 123/187 (65%) Frame = -1 Query: 610 EEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTD 431 + GDLGPVYG QWR + G DQ+ ++++IK NPD RR+++SAWN + Sbjct: 86 DNGDLGPVYGKQWRRWTGP--------DGVEIDQMQWLVDEIKRNPDSRRLVISAWNVGE 137 Query: 430 LKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPG 251 L +MAL PCH QFYV NG+LSCQ+YQRS D+ LGVPFNIASY+LLT M+AQ L G Sbjct: 138 LPQMALMPCHSLFQFYVVNGKLSCQLYQRSGDIFLGVPFNIASYALLTHMVAQATGLGVG 197 Query: 250 EFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQK 71 +FVH +GDAH+YS H + EQL + P+ P L++NP D+ +F D + YDPH Sbjct: 198 DFVHTLGDAHLYSNHFEQAREQLTRTPRALPSLRLNPEVTDLFAFRFEDIAIEGYDPHPA 257 Query: 70 IEMKMAV 50 I+ +AV Sbjct: 258 IKAPVAV 264
>TYSY_MYCGA (Q9XC19) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 289 Score = 192 bits (487), Expect = 8e-49 Identities = 98/189 (51%), Positives = 126/189 (66%), Gaps = 1/189 (0%) Frame = -1 Query: 613 REEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPT 434 ++ G LGPVYG QWR F G DQ+ VIN+IK NP RR+I+SAWNP Sbjct: 114 QQYGKLGPVYGKQWRDFN-------------GVDQIEWVINEIKTNPFSRRLIVSAWNPG 160 Query: 433 DLKKMALPPCHMFAQFYV-ENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLS 257 ++K+MALPPCH F QF+V E E+S Q+YQRS D+ LGVPFNIASYSLL M+AQV L Sbjct: 161 EIKEMALPPCHSFFQFFVNEKYEISLQLYQRSGDLFLGVPFNIASYSLLLLMVAQVTGLK 220 Query: 256 PGEFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPH 77 P EF+H IGD H+YS H++ ++ QLQ++PK P + +NP K+I F D L Y+ H Sbjct: 221 PAEFIHTIGDTHIYSNHLEQVKIQLQREPKKLPKVTLNPDIKNIFDFRFEDISLENYEHH 280 Query: 76 QKIEMKMAV 50 I+ K+AV Sbjct: 281 DPIKGKVAV 289
>TYSY_ECOLI (P0A884) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 264 Score = 190 bits (483), Expect = 2e-48 Identities = 94/187 (50%), Positives = 123/187 (65%) Frame = -1 Query: 610 EEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTD 431 E GDLGPVYG QWR + G+ DQ+ V+N++KN+PD RRII+SAWN + Sbjct: 86 ENGDLGPVYGKQWRAWPTP--------DGRHIDQITTVLNQLKNDPDSRRIIVSAWNVGE 137 Query: 430 LKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPG 251 L KMAL PCH F QFYV +G+LSCQ+YQRS D+ LG+PFNIASY+LL M+AQ CDL G Sbjct: 138 LDKMALAPCHAFFQFYVADGKLSCQLYQRSCDVFLGLPFNIASYALLVHMMAQQCDLEVG 197 Query: 250 EFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQK 71 +FV GD H+YS H+ QL ++P+P P L I + I + DF++ YDPH Sbjct: 198 DFVWTGGDTHLYSNHMDQTHLQLSREPRPLPKLIIKRKPESIFDYRFEDFEIEGYDPHPG 257 Query: 70 IEMKMAV 50 I+ +A+ Sbjct: 258 IKAPVAI 264
>TYSY_ECOL6 (P0A885) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 264 Score = 190 bits (483), Expect = 2e-48 Identities = 94/187 (50%), Positives = 123/187 (65%) Frame = -1 Query: 610 EEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTD 431 E GDLGPVYG QWR + G+ DQ+ V+N++KN+PD RRII+SAWN + Sbjct: 86 ENGDLGPVYGKQWRAWPTP--------DGRHIDQITTVLNQLKNDPDSRRIIVSAWNVGE 137 Query: 430 LKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPG 251 L KMAL PCH F QFYV +G+LSCQ+YQRS D+ LG+PFNIASY+LL M+AQ CDL G Sbjct: 138 LDKMALAPCHAFFQFYVADGKLSCQLYQRSCDVFLGLPFNIASYALLVHMMAQQCDLEVG 197 Query: 250 EFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQK 71 +FV GD H+YS H+ QL ++P+P P L I + I + DF++ YDPH Sbjct: 198 DFVWTGGDTHLYSNHMDQTHLQLSREPRPLPKLIIKRKPESIFDYRFEDFEIEGYDPHPG 257 Query: 70 IEMKMAV 50 I+ +A+ Sbjct: 258 IKAPVAI 264
>TYSY_ECO57 (P0A886) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 264 Score = 190 bits (483), Expect = 2e-48 Identities = 94/187 (50%), Positives = 123/187 (65%) Frame = -1 Query: 610 EEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTD 431 E GDLGPVYG QWR + G+ DQ+ V+N++KN+PD RRII+SAWN + Sbjct: 86 ENGDLGPVYGKQWRAWPTP--------DGRHIDQITTVLNQLKNDPDSRRIIVSAWNVGE 137 Query: 430 LKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPG 251 L KMAL PCH F QFYV +G+LSCQ+YQRS D+ LG+PFNIASY+LL M+AQ CDL G Sbjct: 138 LDKMALAPCHAFFQFYVADGKLSCQLYQRSCDVFLGLPFNIASYALLVHMMAQQCDLEVG 197 Query: 250 EFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQK 71 +FV GD H+YS H+ QL ++P+P P L I + I + DF++ YDPH Sbjct: 198 DFVWTGGDTHLYSNHMDQTHLQLSREPRPLPKLIIKRKPESIFDYRFEDFEIEGYDPHPG 257 Query: 70 IEMKMAV 50 I+ +A+ Sbjct: 258 IKAPVAI 264
>TYSY_XANOR (Q5GWB5) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 264 Score = 190 bits (482), Expect = 3e-48 Identities = 92/187 (49%), Positives = 122/187 (65%) Frame = -1 Query: 610 EEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTD 431 + GDLGPVYG QWR + G DQ+ ++++IK NPD RR+++SAWN + Sbjct: 86 DNGDLGPVYGKQWRRWTGP--------DGVEIDQMQWLVDEIKRNPDSRRLVISAWNVGE 137 Query: 430 LKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPG 251 L +MAL PCH QFYV NG+LSCQ+YQRS D+ LGVPFNIASY+LLT M+AQ L G Sbjct: 138 LPQMALMPCHSLFQFYVVNGKLSCQLYQRSGDIFLGVPFNIASYALLTHMVAQATGLGVG 197 Query: 250 EFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQK 71 +FVH +GDAH+YS H +QL + P+ P L++NP D+ +F D + YDPH Sbjct: 198 DFVHTLGDAHLYSNHFDQARKQLTRTPRALPTLRLNPEVTDLFAFRFEDIAIEGYDPHPA 257 Query: 70 IEMKMAV 50 I+ +AV Sbjct: 258 IKAPVAV 264
>TYSY_SHIFL (P48464) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 264 Score = 190 bits (482), Expect = 3e-48 Identities = 93/187 (49%), Positives = 123/187 (65%) Frame = -1 Query: 610 EEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTD 431 E GDLGPVYG QWR + G+ DQ+ V+N++KN+PD RRII+SAWN + Sbjct: 86 ENGDLGPVYGKQWRAWPTP--------DGRHIDQITTVLNQLKNDPDSRRIIVSAWNVGE 137 Query: 430 LKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPG 251 L KMAL PCH F QFYV +G+LSCQ+YQRS D+ LG+PFNIASY+LL M+AQ CDL G Sbjct: 138 LDKMALAPCHAFFQFYVADGKLSCQLYQRSCDVFLGLPFNIASYALLVHMMAQQCDLEVG 197 Query: 250 EFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQK 71 +FV GD H+YS H+ QL ++P+P P L I + I + DF++ YDPH Sbjct: 198 DFVWTGGDTHLYSNHMDQTHLQLSREPRPLPKLIIKRKPESIFDYRFEDFEIEGYDPHPG 257 Query: 70 IEMKMAV 50 ++ +A+ Sbjct: 258 VKAPVAI 264
>TYSB_BACSU (P11044) Thymidylate synthase B (EC 2.1.1.45) (TS B) (TSase B)| Length = 264 Score = 190 bits (482), Expect = 3e-48 Identities = 93/188 (49%), Positives = 125/188 (66%), Gaps = 1/188 (0%) Frame = -1 Query: 610 EEGDLGPVYGFQWRHF-GAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPT 434 E G+LGPVYG QWR + GA+ G+ DQ++ +I IK NP+ RR+I+SAWN Sbjct: 86 ENGELGPVYGSQWRSWRGAD---------GETIDQISRLIEDIKTNPNSRRLIVSAWNVG 136 Query: 433 DLKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSP 254 ++ KMALPPCH QFYV +G+LSCQ+YQRSAD+ LGVPFNIASY+LLT +IA V L P Sbjct: 137 EIDKMALPPCHCLFQFYVSDGKLSCQLYQRSADVFLGVPFNIASYALLTMIIAHVTGLEP 196 Query: 253 GEFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQ 74 GEF+H GD H+Y H++ + QL++ +P P L+ I +F DF + YDPH Sbjct: 197 GEFIHTFGDVHIYQNHIEQVNLQLERDVRPLPQLRFARKVDSIFNFAFEDFIIEDYDPHP 256 Query: 73 KIEMKMAV 50 I+ ++V Sbjct: 257 HIKGAVSV 264
>TYSY_BIFLO (Q8G3T9) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 266 Score = 189 bits (481), Expect = 4e-48 Identities = 96/187 (51%), Positives = 124/187 (66%) Frame = -1 Query: 610 EEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTD 431 E GDLGPVYG QWR + A + + DQ+++V++ IK++PD RR+I+SAWNP + Sbjct: 85 ENGDLGPVYGVQWRSWPAPTPED----PNRTIDQISNVLDLIKHHPDSRRMIVSAWNPAE 140 Query: 430 LKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPG 251 ++KMALPPCH QFYV + +LSCQ+YQRS DM LGVPFNIASYSLLT M+AQ L PG Sbjct: 141 VEKMALPPCHALFQFYVADDKLSCQLYQRSCDMFLGVPFNIASYSLLTMMMAQQAGLKPG 200 Query: 250 EFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQK 71 EFV GD HVY HV EQL ++P P+P ++I D + DFK+ Y H Sbjct: 201 EFVWTGGDCHVYDNHVDQFLEQLGRKPYPYPTIEIRKADSLFD-YQYEDFKVVGYQHHPT 259 Query: 70 IEMKMAV 50 I+ +AV Sbjct: 260 IKAPVAV 266
>TYSY_YERPS (Q667F9) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 264 Score = 189 bits (481), Expect = 4e-48 Identities = 94/187 (50%), Positives = 126/187 (67%) Frame = -1 Query: 610 EEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTD 431 E GDLGP+YG QWR +GA AD G+ DQL++V+N++K +PD RRII+SAWN + Sbjct: 86 ENGDLGPIYGKQWRAWGA------AD--GRKIDQLSNVVNQLKQDPDSRRIIVSAWNVGE 137 Query: 430 LKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPG 251 L +MAL PCH F QFYV +G+LSCQ+YQRS D+ LG+PFNIASY+LL M+AQ CDL+ G Sbjct: 138 LDQMALAPCHAFFQFYVADGKLSCQLYQRSCDVFLGLPFNIASYALLVHMMAQQCDLAVG 197 Query: 250 EFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQK 71 +FV GD H+YS H+ QL ++P+ P L I + + DF + YDPH Sbjct: 198 DFVWTGGDTHLYSNHIDQTHLQLSREPRALPKLVIKRKPDSLFDYHFDDFDIEGYDPHPG 257 Query: 70 IEMKMAV 50 I+ +A+ Sbjct: 258 IKAPIAI 264
>TYSY_COREF (Q8FR47) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 267 Score = 189 bits (480), Expect = 5e-48 Identities = 92/187 (49%), Positives = 123/187 (65%) Frame = -1 Query: 610 EEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTD 431 E+G+LGPVYG QWR + G+ DQ++ + +KNNPD RR I+SAWN ++ Sbjct: 90 EDGELGPVYGVQWRSWPTP--------DGRHIDQISRALEMLKNNPDSRRNIVSAWNVSE 141 Query: 430 LKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPG 251 L+ MALPPCH+ Q YV +G+LSCQ+YQRSADM LGVPFNIASY+LLT M AQ DL G Sbjct: 142 LENMALPPCHLLFQLYVADGKLSCQLYQRSADMFLGVPFNIASYALLTHMFAQQADLEVG 201 Query: 250 EFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQK 71 EF+ GD H+Y H + ++EQL + +P+P L++N D + D ++ YDPH Sbjct: 202 EFIWTGGDCHIYDNHTEQVDEQLSRAARPYPTLELNKAASLFD-YTFEDIAVSNYDPHPL 260 Query: 70 IEMKMAV 50 I K+AV Sbjct: 261 IRGKVAV 267
>TYSY_YERPE (Q8ZHV1) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 264 Score = 189 bits (480), Expect = 5e-48 Identities = 94/187 (50%), Positives = 126/187 (67%) Frame = -1 Query: 610 EEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTD 431 E GDLGP+YG QWR +GA AD G+ DQL++V+N++K +PD RRII+SAWN + Sbjct: 86 ENGDLGPIYGKQWRAWGA------AD--GRKIDQLSNVVNQLKQDPDSRRIIVSAWNVGE 137 Query: 430 LKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPG 251 L +MAL PCH F QFYV +G+LSCQ+YQRS D+ LG+PFNIASY+LL M+AQ CDL+ G Sbjct: 138 LDQMALAPCHAFFQFYVADGKLSCQLYQRSCDVFLGLPFNIASYALLVHMMAQQCDLAVG 197 Query: 250 EFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQK 71 +FV GD H+YS H+ QL ++P+ P L I + + DF + YDPH Sbjct: 198 DFVWTGGDTHLYSNHIDQAHLQLSREPRVLPKLVIKRKPDSLFDYHFDDFDIEGYDPHPG 257 Query: 70 IEMKMAV 50 I+ +A+ Sbjct: 258 IKAPIAI 264
>TYSB_BACAM (P54081) Thymidylate synthase B (EC 2.1.1.45) (TS B) (TSase B)| Length = 264 Score = 189 bits (480), Expect = 5e-48 Identities = 95/188 (50%), Positives = 124/188 (65%), Gaps = 1/188 (0%) Frame = -1 Query: 610 EEGDLGPVYGFQWRHF-GAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPT 434 E G+LGPVYG QWR + GA+ G+ DQ++ +I+ IK NP+ RR+I+SAWN Sbjct: 86 ENGELGPVYGSQWRSWRGAD---------GETIDQISRLIHDIKTNPNSRRLIVSAWNVG 136 Query: 433 DLKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSP 254 ++ +MALPPCH QFYV +G+LSCQ+YQRSAD+ LGVPFNIASY+LLT MIA V L P Sbjct: 137 EIDRMALPPCHCLFQFYVADGKLSCQLYQRSADVFLGVPFNIASYALLTMMIAHVTGLEP 196 Query: 253 GEFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQ 74 GEFVH GD H+Y HV+ + QL + +P P L+ I F DF + YDPH Sbjct: 197 GEFVHTFGDVHIYQNHVEQVNLQLTRDVRPLPKLRFARNVDSIFDFAFEDFIIEDYDPHP 256 Query: 73 KIEMKMAV 50 I+ ++V Sbjct: 257 HIKGAVSV 264
>TYSY_ONYPE (Q6YQT0) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 288 Score = 189 bits (479), Expect = 7e-48 Identities = 91/175 (52%), Positives = 120/175 (68%) Frame = -1 Query: 610 EEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTD 431 + G+LGPVYG QWR F G DQ+ +I++IK NP+ RR+IL++WNP Sbjct: 115 KHGNLGPVYGKQWRDFN-------------GVDQIKFLISEIKTNPNSRRLILNSWNPPL 161 Query: 430 LKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPG 251 L +MALPPCH+ QFYV G+LS Q+YQRS D+ LG+PFNIASYSLL M+AQV +L P Sbjct: 162 LNQMALPPCHVLIQFYVHQGKLSLQLYQRSGDVFLGIPFNIASYSLLLMMVAQVTNLQPY 221 Query: 250 EFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACY 86 EF+H +GDAH+YS H+ ++ Q+Q+ PK P + +NP K+ID F SDF L Y Sbjct: 222 EFIHTLGDAHIYSNHLAQVQTQIQRTPKKLPQMILNPDIKNIDDFKFSDFTLQNY 276
>TYSY_LACAC (Q5FKL6) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 318 Score = 189 bits (479), Expect = 7e-48 Identities = 94/188 (50%), Positives = 123/188 (65%) Frame = -1 Query: 613 REEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPT 434 ++ G+LG VYG QWRH+ G DQ+ +VI +IKNNPD RR+I++AWNP Sbjct: 139 KKYGNLGDVYGAQWRHWQKR--------DGSFIDQIENVIEQIKNNPDSRRMIVTAWNPE 190 Query: 433 DLKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSP 254 D+ ALPPCH+ QFYV +G++S Q+YQRS DM LGVPFNIASY+LL MIA+ L Sbjct: 191 DVPTSALPPCHVMFQFYVVDGKISVQLYQRSGDMFLGVPFNIASYALLLNMIARETGLQV 250 Query: 253 GEFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQ 74 GEF+H +GDAH+YS H ++E L ++P P L +NP KK I+ F D KL Y H Sbjct: 251 GEFIHTLGDAHIYSNHFSQVKEMLSRKPYESPQLWLNPEKKHIEDFDMQDIKLVDYKHHG 310 Query: 73 KIEMKMAV 50 I+ +AV Sbjct: 311 TIKAPVAV 318
>TYSY_PHOLL (Q7N8U4) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 264 Score = 187 bits (476), Expect = 2e-47 Identities = 94/187 (50%), Positives = 125/187 (66%) Frame = -1 Query: 610 EEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTD 431 E GDLGPVYG QWR +G AD G+ DQL V+ ++K++PD RRII+SAWN + Sbjct: 86 ENGDLGPVYGKQWRAWGT------AD--GRQIDQLKTVLEQLKSDPDSRRIIVSAWNVGE 137 Query: 430 LKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPG 251 L KMAL PCH F QFYV +G+LSCQ+YQRS D+ LG+PFNIASY+LL M+AQ CDL G Sbjct: 138 LDKMALAPCHAFFQFYVADGKLSCQLYQRSCDVFLGLPFNIASYALLVHMMAQQCDLEVG 197 Query: 250 EFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQK 71 +FV GD H+YS H++ + QL ++P+ P L I + + DF++ YDPH Sbjct: 198 DFVWTGGDTHLYSNHMEQTKLQLSREPRSLPKLVIKRKPASLFDYKFDDFEIVDYDPHPG 257 Query: 70 IEMKMAV 50 I+ +A+ Sbjct: 258 IKAPVAI 264
>TYSY_ERWCT (Q6D8I6) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 264 Score = 187 bits (475), Expect = 2e-47 Identities = 93/187 (49%), Positives = 125/187 (66%) Frame = -1 Query: 610 EEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTD 431 E GDLGPVYG QWR +GA AD G+ DQL +V+ +++ +PD RRII+SAWN + Sbjct: 86 ENGDLGPVYGKQWRSWGA------AD--GRQIDQLKNVLTQLRQDPDSRRIIVSAWNVGE 137 Query: 430 LKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPG 251 L KMAL PCH F QFYV +G+LSCQ+YQRS D+ LG+PFNIASY+LL M+AQ CDL G Sbjct: 138 LDKMALAPCHAFFQFYVADGKLSCQLYQRSCDIFLGLPFNIASYALLVHMVAQQCDLDVG 197 Query: 250 EFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQK 71 +FV GD H+Y+ H++ QL ++P+ P L I + + DF++ YDPH Sbjct: 198 DFVWTGGDTHLYNNHMEQTHLQLSREPRALPKLVIKRRPDTLFDYRFEDFEIEGYDPHPA 257 Query: 70 IEMKMAV 50 I+ +A+ Sbjct: 258 IKAPVAI 264
>TYSY_RALSO (Q8Y0U6) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 264 Score = 187 bits (474), Expect = 3e-47 Identities = 92/186 (49%), Positives = 123/186 (66%) Frame = -1 Query: 607 EGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTDL 428 EG+LGP+YG+QWR + +G+ DQ+A++I +IK NPD RR+I+SAWN D+ Sbjct: 87 EGELGPIYGYQWRSWPTP--------SGEHIDQIAELIAQIKRNPDSRRLIVSAWNVADI 138 Query: 427 KKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPGE 248 +M LPPCH F QFYV +G+LSCQ+YQRSAD+ LGVPFNIASY+LLT MIAQ L G+ Sbjct: 139 PRMKLPPCHAFFQFYVADGKLSCQLYQRSADIFLGVPFNIASYALLTHMIAQQTGLDVGD 198 Query: 247 FVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQKI 68 FV GD H+Y+ H + +E QL + P P P L I I + DF++ Y+ H I Sbjct: 199 FVWTGGDCHLYNNHFEQVETQLARTPLPLPKLHIKRKPDSIFDYRYEDFEIVGYESHPAI 258 Query: 67 EMKMAV 50 + +AV Sbjct: 259 KAPVAV 264
>TYSY_SALTY (Q8ZMA9) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 264 Score = 186 bits (473), Expect = 4e-47 Identities = 92/187 (49%), Positives = 123/187 (65%) Frame = -1 Query: 610 EEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTD 431 E GDLGPVYG QWR + G+ DQ+A V++++KN+PD RRII+SAWN + Sbjct: 86 ENGDLGPVYGKQWRAWPTP--------DGRHIDQIATVLSQLKNDPDSRRIIVSAWNVGE 137 Query: 430 LKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPG 251 L KMAL PCH F QFYV +G+LSCQ+YQRS D+ LG+PFNIASY+LL M+AQ CDL G Sbjct: 138 LDKMALAPCHAFFQFYVADGKLSCQLYQRSCDVFLGLPFNIASYALLVHMMAQQCDLDVG 197 Query: 250 EFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQK 71 +FV GD H+YS H++ QL ++P+ P L I + + DF++ YDPH Sbjct: 198 DFVWTGGDTHLYSNHMEQTHLQLSREPRALPKLVIKRKPDSLFDYRFDDFEIEGYDPHPG 257 Query: 70 IEMKMAV 50 I+ +A+ Sbjct: 258 IKAPVAI 264
>TYSY_SALTI (Q8Z412) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 264 Score = 186 bits (473), Expect = 4e-47 Identities = 92/187 (49%), Positives = 123/187 (65%) Frame = -1 Query: 610 EEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTD 431 E GDLGPVYG QWR + G+ DQ+A V++++KN+PD RRII+SAWN + Sbjct: 86 ENGDLGPVYGKQWRAWPTP--------DGRHIDQIATVLSQLKNDPDSRRIIVSAWNVGE 137 Query: 430 LKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPG 251 L KMAL PCH F QFYV +G+LSCQ+YQRS D+ LG+PFNIASY+LL M+AQ CDL G Sbjct: 138 LDKMALAPCHAFFQFYVADGKLSCQLYQRSCDVFLGLPFNIASYALLVHMMAQQCDLDVG 197 Query: 250 EFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQK 71 +FV GD H+YS H++ QL ++P+ P L I + + DF++ YDPH Sbjct: 198 DFVWTGGDTHLYSNHMEQTHLQLSREPRALPKLVIKRKPDSLFDYRFDDFEIEGYDPHPG 257 Query: 70 IEMKMAV 50 I+ +A+ Sbjct: 258 IKAPVAI 264
>TYSY_SALPA (Q5PEN6) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 264 Score = 186 bits (473), Expect = 4e-47 Identities = 92/187 (49%), Positives = 123/187 (65%) Frame = -1 Query: 610 EEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTD 431 E GDLGPVYG QWR + G+ DQ+A V++++KN+PD RRII+SAWN + Sbjct: 86 ENGDLGPVYGKQWRAWPTP--------DGRHIDQIATVLSQLKNDPDSRRIIVSAWNVGE 137 Query: 430 LKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPG 251 L KMAL PCH F QFYV +G+LSCQ+YQRS D+ LG+PFNIASY+LL M+AQ CDL G Sbjct: 138 LDKMALAPCHAFFQFYVADGKLSCQLYQRSCDVFLGLPFNIASYALLVHMMAQQCDLDVG 197 Query: 250 EFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQK 71 +FV GD H+YS H++ QL ++P+ P L I + + DF++ YDPH Sbjct: 198 DFVWTGGDTHLYSNHMEQTHLQLSREPRALPKLVIKRKPDSLFDYRFDDFEIEGYDPHPG 257 Query: 70 IEMKMAV 50 I+ +A+ Sbjct: 258 IKAPVAI 264
>TYSY_CORDI (Q6NIF2) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 270 Score = 184 bits (468), Expect = 1e-46 Identities = 93/187 (49%), Positives = 119/187 (63%) Frame = -1 Query: 610 EEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTD 431 EEG+LGPVYG QWR + G+ DQ+A ++ +KNNPD RR I+SAWN D Sbjct: 93 EEGELGPVYGVQWRSWPTP--------DGQHVDQIAQALDILKNNPDSRRNIVSAWNVAD 144 Query: 430 LKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPG 251 L MALPPCH+ Q YV +G+LSCQ+YQRSADM LGVPFNIASYS LT M+AQ L G Sbjct: 145 LNNMALPPCHLLFQLYVADGKLSCQLYQRSADMFLGVPFNIASYSALTHMLAQQAGLKVG 204 Query: 250 EFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQK 71 EF+ GD H+Y H + + QL ++P+P+P L + D + DF + YDPH Sbjct: 205 EFIWTGGDCHIYDNHREQVLTQLSREPRPYPQLTLRKASSIFD-YDFDDFTIEGYDPHPA 263 Query: 70 IEMKMAV 50 I ++AV Sbjct: 264 IRGEVAV 270
>TYSY_LISMO (Q8Y626) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 314 Score = 184 bits (468), Expect = 1e-46 Identities = 90/185 (48%), Positives = 122/185 (65%) Frame = -1 Query: 604 GDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTDLK 425 G+LG +YG QWR + G+ DQLAD+I IK NP+ RR+I+SAWNP D+ Sbjct: 138 GELGNIYGKQWREWKTSQ--------GETIDQLADLIEMIKTNPNSRRLIVSAWNPEDIP 189 Query: 424 KMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPGEF 245 MALPPCH QFYV +G+LSCQ+YQRSAD+ LGVPFNIASY+LLT +IA+ L GEF Sbjct: 190 NMALPPCHSLFQFYVADGKLSCQLYQRSADIFLGVPFNIASYALLTHLIAREVGLDVGEF 249 Query: 244 VHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQKIE 65 +H +GDAH+Y+ H++ ++EQL + P P L ++ I F +D L Y+P I+ Sbjct: 250 IHTMGDAHLYNNHIEQVKEQLSRTPHALPKLVLSDKPATIFDFEVADISLDGYNPDPSIK 309 Query: 64 MKMAV 50 ++V Sbjct: 310 APISV 314
>TYSY_STAES (P0C0M5) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 318 Score = 184 bits (467), Expect = 2e-46 Identities = 94/188 (50%), Positives = 122/188 (64%) Frame = -1 Query: 613 REEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPT 434 ++ G+LG VYG QWR + D G +DQL VI +IK NP+ RR I+SAWNPT Sbjct: 140 KKYGNLGNVYGKQWRDW--------EDKNGNHYDQLKSVIQQIKTNPNSRRHIVSAWNPT 191 Query: 433 DLKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSP 254 ++ MALPPCH QFYV+ G+L+CQ+YQRSAD+ LGVPFNIASY+LLT ++A+ C L Sbjct: 192 EIDSMALPPCHTMFQFYVQEGKLNCQLYQRSADIFLGVPFNIASYALLTHLVAKECGLEV 251 Query: 253 GEFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQ 74 GEF+H GDAH+YS H+ A+ QL + P LKIN K I D +L Y+ H Sbjct: 252 GEFIHTFGDAHIYSNHMDAIHTQLSRDSYLPPQLKIN-TDKSIFDINYEDLELINYESHP 310 Query: 73 KIEMKMAV 50 I+ +AV Sbjct: 311 AIKAPIAV 318
>TYSY_STAEQ (Q5HMP6) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 318 Score = 184 bits (467), Expect = 2e-46 Identities = 94/188 (50%), Positives = 122/188 (64%) Frame = -1 Query: 613 REEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPT 434 ++ G+LG VYG QWR + D G +DQL VI +IK NP+ RR I+SAWNPT Sbjct: 140 KKYGNLGNVYGKQWRDW--------EDKNGNHYDQLKSVIQQIKTNPNSRRHIVSAWNPT 191 Query: 433 DLKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSP 254 ++ MALPPCH QFYV+ G+L+CQ+YQRSAD+ LGVPFNIASY+LLT ++A+ C L Sbjct: 192 EIDSMALPPCHTMFQFYVQEGKLNCQLYQRSADIFLGVPFNIASYALLTHLVAKECGLEV 251 Query: 253 GEFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQ 74 GEF+H GDAH+YS H+ A+ QL + P LKIN K I D +L Y+ H Sbjct: 252 GEFIHTFGDAHIYSNHMDAIHTQLSRDSYLPPQLKIN-TDKSIFDINYEDLELINYESHP 310 Query: 73 KIEMKMAV 50 I+ +AV Sbjct: 311 AIKAPIAV 318
>TYSY_STAAU (P0A0M5) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 318 Score = 184 bits (467), Expect = 2e-46 Identities = 94/188 (50%), Positives = 122/188 (64%) Frame = -1 Query: 613 REEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPT 434 ++ G+LG VYG QWR + D G +DQL VI +IK NP+ RR I+SAWNPT Sbjct: 140 KKYGNLGNVYGKQWRDW--------EDKNGNHYDQLKSVIQQIKTNPNSRRHIVSAWNPT 191 Query: 433 DLKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSP 254 ++ MALPPCH QFYV+ G+L+CQ+YQRSAD+ LGVPFNIASY+LLT ++A+ C L Sbjct: 192 EIDSMALPPCHTMFQFYVQEGKLNCQLYQRSADIFLGVPFNIASYALLTHLVAKECGLEV 251 Query: 253 GEFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQ 74 GEF+H GDAH+YS H+ A+ QL + P LKIN K I D +L Y+ H Sbjct: 252 GEFIHTFGDAHIYSNHMDAIHTQLSRDSYLPPQLKIN-TDKSIFDINYEDLELINYESHP 310 Query: 73 KIEMKMAV 50 I+ +AV Sbjct: 311 AIKAPIAV 318
>TYSY_MYCPN (P78029) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 287 Score = 184 bits (467), Expect = 2e-46 Identities = 91/185 (49%), Positives = 122/185 (65%) Frame = -1 Query: 604 GDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTDLK 425 G+LGPVYG QWR F G DQL VI +IK NP RR+I+S+WNP ++ Sbjct: 117 GNLGPVYGKQWRDFN-------------GVDQLKKVIAQIKVNPFSRRLIVSSWNPNEVD 163 Query: 424 KMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPGEF 245 +M LPPCH QFYV++G+LSCQ+YQRS D+ LG+PFNIASYSLL ++A+ +L PG F Sbjct: 164 QMLLPPCHSLYQFYVQDGQLSCQLYQRSGDIFLGIPFNIASYSLLVYLVAKETNLKPGSF 223 Query: 244 VHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQKIE 65 VH IGDAH+Y H++ ++ QL +QPKP P + + K I + D +L YD H I+ Sbjct: 224 VHTIGDAHIYENHLEQIKLQLTRQPKPLPKVVLKS-DKSIFDYQFDDIELVDYDHHPTIK 282 Query: 64 MKMAV 50 ++AV Sbjct: 283 GEVAV 287
>TYSY_LISIN (Q92AD4) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 314 Score = 184 bits (467), Expect = 2e-46 Identities = 90/185 (48%), Positives = 122/185 (65%) Frame = -1 Query: 604 GDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTDLK 425 G+LG +YG QWR + G+ DQLAD+I IK NP+ RR+I+SAWNP D+ Sbjct: 138 GELGNIYGKQWREWKTSQ--------GETIDQLADLIEMIKTNPNSRRLIVSAWNPEDIP 189 Query: 424 KMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPGEF 245 MALPPCH QFYV +G+LSCQ+YQRSAD+ LGVPFNIASY+LLT +IA+ L GEF Sbjct: 190 NMALPPCHSLFQFYVADGKLSCQLYQRSADIFLGVPFNIASYALLTHLIAREVGLDVGEF 249 Query: 244 VHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQKIE 65 +H +GDAH+Y+ H++ ++EQL + P P L ++ I F +D L Y+P I+ Sbjct: 250 IHTMGDAHLYNNHIEQVKEQLSRTPHALPKLVLSDKPATIFDFEVADISLDGYNPDPAIK 309 Query: 64 MKMAV 50 ++V Sbjct: 310 APISV 314
>TYSY_LISMF (Q71YE1) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 314 Score = 184 bits (466), Expect = 2e-46 Identities = 90/185 (48%), Positives = 122/185 (65%) Frame = -1 Query: 604 GDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTDLK 425 G+LG +YG QWR + G+ DQLAD+I IK NP+ RR+I+SAWNP D+ Sbjct: 138 GELGNIYGKQWREWKTSQ--------GETIDQLADLIEMIKTNPNSRRLIVSAWNPEDIP 189 Query: 424 KMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPGEF 245 MALPPCH QFYV +G+LSCQ+YQRSAD+ LGVPFNIASY+LLT +IA+ L GEF Sbjct: 190 NMALPPCHSLFQFYVADGKLSCQLYQRSADIFLGVPFNIASYALLTHLIAREVGLEVGEF 249 Query: 244 VHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQKIE 65 +H +GDAH+Y+ H++ ++EQL + P P L ++ I F +D L Y+P I+ Sbjct: 250 IHTMGDAHLYNNHIEQVKEQLSRTPHKLPKLVLSDKPATIFDFDVADISLDGYNPDPAIK 309 Query: 64 MKMAV 50 ++V Sbjct: 310 APISV 314
>TYSY_PROAC (Q6A761) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 269 Score = 183 bits (465), Expect = 3e-46 Identities = 94/193 (48%), Positives = 123/193 (63%), Gaps = 6/193 (3%) Frame = -1 Query: 610 EEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTD 431 E GDLGPVYG QWR + + + DQ+A+V+ +I+ NP RR I+SAWN + Sbjct: 86 ENGDLGPVYGHQWRSWPDDDGTI---------DQIANVVEQIRTNPWSRRHIVSAWNVAE 136 Query: 430 LKKMALPPCHMFAQFYVENGE------LSCQMYQRSADMGLGVPFNIASYSLLTCMIAQV 269 +K+MALPPCH QFYV + LSCQ+YQRS D LGVPFNIASY+LLT ++A V Sbjct: 137 IKEMALPPCHTLFQFYVTPDDRGTPTWLSCQLYQRSGDTFLGVPFNIASYALLTHLVASV 196 Query: 268 CDLSPGEFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLAC 89 L P FVH +GDAHVY H+ + EQL+++P+ P L +NP +DID F SD L Sbjct: 197 TGLKPLRFVHTLGDAHVYLNHLDQVHEQLKRKPRHRPTLTVNPGIRDIDGFELSDITLTG 256 Query: 88 YDPHQKIEMKMAV 50 YDP+ + +AV Sbjct: 257 YDPYPALPAPIAV 269
>TYSY_LEGPL (Q5WSU5) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 264 Score = 183 bits (465), Expect = 3e-46 Identities = 94/185 (50%), Positives = 119/185 (64%) Frame = -1 Query: 604 GDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTDLK 425 GDLGPVYG QWR + AD G DQL+DV+ +IK+NPD RR+I+SAWN +L Sbjct: 88 GDLGPVYGKQWRSWPT------AD--GGTIDQLSDVVQQIKSNPDSRRLIVSAWNVGELD 139 Query: 424 KMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPGEF 245 KMAL PCH QFYV N +LSCQ+YQRSAD+ LGVPFNIASYSLLT M+AQ C+L EF Sbjct: 140 KMALMPCHALFQFYVANNKLSCQLYQRSADVFLGVPFNIASYSLLTHMVAQQCNLDVAEF 199 Query: 244 VHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQKIE 65 + GD H+Y H++ + QL ++P P P L I + + DF+ Y H I+ Sbjct: 200 IWTGGDCHLYLNHLEQAQTQLTREPLPLPSLAIKRKPASLFDYAYEDFEFVNYQSHPAIK 259 Query: 64 MKMAV 50 +AV Sbjct: 260 APIAV 264
>TYSY_LEIXX (Q6AFI0) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 269 Score = 183 bits (464), Expect = 4e-46 Identities = 91/187 (48%), Positives = 117/187 (62%) Frame = -1 Query: 610 EEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTD 431 E G+LGPVYG QWR + + G DQ+ V++ ++ +PD RRII+SAWN D Sbjct: 91 ERGELGPVYGVQWRSWPSP--------DGTHIDQIQQVVDTLRRDPDSRRIIVSAWNVAD 142 Query: 430 LKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPG 251 + MAL PCH F QFYV +G+LSCQ+YQRSADM LGVPFNIASY+LLT M+AQ L PG Sbjct: 143 IPDMALAPCHAFFQFYVADGKLSCQLYQRSADMFLGVPFNIASYALLTLMVAQQVGLEPG 202 Query: 250 EFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQK 71 EFV GD H+Y H++ + EQL + P P P L+ + + + DF L Y H Sbjct: 203 EFVWTGGDVHIYDNHIEQVNEQLSRNPFPAPALRFARRPESVFDYRYEDFVLEGYRHHPA 262 Query: 70 IEMKMAV 50 I +AV Sbjct: 263 IRAAVAV 269
>TYSY_CORGL (Q8NS38) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 266 Score = 183 bits (464), Expect = 4e-46 Identities = 89/187 (47%), Positives = 122/187 (65%) Frame = -1 Query: 610 EEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTD 431 E+G+LGPVYG QWR + G+ DQ++ + ++NNPD RR I+SAWN ++ Sbjct: 89 EDGELGPVYGVQWRSWPTP--------DGRHIDQISGALETLRNNPDSRRNIVSAWNVSE 140 Query: 430 LKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPG 251 L+ MALPPCH+ Q YV +G+LSCQ+YQRSADM LGVPFNIASY+LLT M AQ L G Sbjct: 141 LENMALPPCHLLFQLYVADGKLSCQLYQRSADMFLGVPFNIASYALLTHMFAQQAGLEVG 200 Query: 250 EFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQK 71 EF+ GD H+Y H + + EQL ++ +P+P L++N + + D ++ YDPH Sbjct: 201 EFIWTGGDCHIYDNHKEQVAEQLSREARPYPTLELNKAASMFE-YSFDDITVSGYDPHPL 259 Query: 70 IEMKMAV 50 I K+AV Sbjct: 260 IRGKVAV 266
>TYSY_LEGPA (Q5X119) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 264 Score = 182 bits (463), Expect = 5e-46 Identities = 94/185 (50%), Positives = 119/185 (64%) Frame = -1 Query: 604 GDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTDLK 425 GDLGPVYG QWR + AD G DQL+DV+ +IK+NPD RR+I+SAWN +L Sbjct: 88 GDLGPVYGKQWRSWPT------AD--GHTIDQLSDVVQQIKSNPDSRRLIVSAWNVGELD 139 Query: 424 KMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPGEF 245 KMAL PCH QFYV N +LSCQ+YQRSAD+ LGVPFNIASYSLLT M+AQ C+L EF Sbjct: 140 KMALMPCHALFQFYVANNKLSCQLYQRSADVFLGVPFNIASYSLLTHMVAQQCNLDVAEF 199 Query: 244 VHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQKIE 65 + GD H+Y H++ + QL ++P P P L I + + DF+ Y H I+ Sbjct: 200 IWTGGDCHLYLNHLEQAQIQLTREPLPLPSLTIKRKPASLFDYAYEDFEFLNYQSHPAIK 259 Query: 64 MKMAV 50 +AV Sbjct: 260 APIAV 264
>TYSY_XENNE (Q6REU8) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 264 Score = 182 bits (462), Expect = 7e-46 Identities = 91/187 (48%), Positives = 124/187 (66%) Frame = -1 Query: 610 EEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTD 431 E GDLGPVYG QWR +G+ AD G+ DQL V+ ++K +PD RRII+SAWN + Sbjct: 86 ENGDLGPVYGKQWRAWGS------AD--GRHIDQLTQVLEQLKGDPDSRRIIVSAWNVGE 137 Query: 430 LKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPG 251 L KMAL PCH F QFYV +G+LSCQ+YQRS D+ LG+PFNIASY+LL M+AQ C+L G Sbjct: 138 LDKMALAPCHAFFQFYVADGKLSCQLYQRSCDVFLGLPFNIASYALLVHMMAQQCNLDVG 197 Query: 250 EFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQK 71 +FV GD H+Y+ H++ QL ++P+ P L I + + DF++ YDP+ Sbjct: 198 DFVWTGGDTHLYNNHLEQTHLQLSREPRALPKLVIKRKPDSLFDYRFEDFEIVDYDPYPG 257 Query: 70 IEMKMAV 50 I+ +A+ Sbjct: 258 IKAPVAI 264
>TYSY_LEGPH (Q5ZRL3) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 264 Score = 182 bits (462), Expect = 7e-46 Identities = 93/185 (50%), Positives = 120/185 (64%) Frame = -1 Query: 604 GDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTDLK 425 GDLGPVYG QWR + AD G+ DQL++V+ +IK+NPD RR+I+SAWN +L Sbjct: 88 GDLGPVYGKQWRSWPT------AD--GRTIDQLSEVVQQIKSNPDSRRLIVSAWNVGELD 139 Query: 424 KMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPGEF 245 KMAL PCH QFYV N +LSCQ+YQRSAD+ LGVPFNIASYSLLT M+AQ C+L EF Sbjct: 140 KMALMPCHALFQFYVANNKLSCQLYQRSADVFLGVPFNIASYSLLTHMVAQQCNLDVAEF 199 Query: 244 VHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQKIE 65 + GD H+Y H++ + QL ++P P P L I + + DF+ Y H I+ Sbjct: 200 IWTGGDCHLYLNHLEQAQIQLTREPLPLPSLAIKRKPASLFDYAYEDFEFLNYQSHPAIK 259 Query: 64 MKMAV 50 +AV Sbjct: 260 APIAV 264
>TYSY_MYCPE (Q8EV81) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 289 Score = 182 bits (462), Expect = 7e-46 Identities = 92/189 (48%), Positives = 125/189 (66%), Gaps = 1/189 (0%) Frame = -1 Query: 613 REEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPT 434 ++ G+LGPVYG QWR+F G DQ+ ++I +IK N RR+I+S WNP+ Sbjct: 114 KQFGELGPVYGRQWRNFN-------------GVDQITNLIEEIKKNKYSRRLIVSVWNPS 160 Query: 433 DLKKMALPPCHMFAQFYVEN-GELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLS 257 ++K M LPPCH QF+V + ELSCQ+YQRSAD+ LGVPFNIASYSLLT MIAQV + + Sbjct: 161 EIKNMLLPPCHCLFQFFVNSKNELSCQLYQRSADLFLGVPFNIASYSLLTYMIAQVTNTT 220 Query: 256 PGEFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPH 77 EFVH IG AH+Y+ H+ ++EQL ++P P L +N K+I F D ++ Y+ H Sbjct: 221 AKEFVHTIGVAHIYNNHIDQVKEQLTREPLQLPTLVLNKNIKNIFDFKIEDIEIKDYNSH 280 Query: 76 QKIEMKMAV 50 I+ K+AV Sbjct: 281 PAIKGKVAV 289
>TYSY_GEOKA (Q5KZ25) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 264 Score = 181 bits (458), Expect = 2e-45 Identities = 91/188 (48%), Positives = 119/188 (63%), Gaps = 1/188 (0%) Frame = -1 Query: 610 EEGDLGPVYGFQWRHF-GAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPT 434 E GDLGP+YG QWR + GA+ GK DQ+A V+ +IK NP+ RR+++SAWN Sbjct: 86 ENGDLGPIYGAQWRSWKGAD---------GKTIDQIAWVVEEIKRNPNSRRLLVSAWNVA 136 Query: 433 DLKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSP 254 +L +M LPPCH QFYV NG LSC QRS D LG+PFNIASY+LLT MIAQ CDL Sbjct: 137 ELDEMKLPPCHYAFQFYVANGRLSCMWQQRSVDTFLGLPFNIASYALLTHMIAQQCDLDV 196 Query: 253 GEFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQ 74 GE + GD H+Y H++ + QL ++P+P P L I I + DF++ Y+PH Sbjct: 197 GELIFTGGDVHLYKNHLEQAKLQLTREPRPLPKLVIKRKPPSIFDYEYDDFEIVGYNPHP 256 Query: 73 KIEMKMAV 50 I+ +AV Sbjct: 257 TIKAPVAV 264
>TYSY_NOCFA (Q5YPL7) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 266 Score = 180 bits (457), Expect = 3e-45 Identities = 89/186 (47%), Positives = 121/186 (65%) Frame = -1 Query: 607 EGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTDL 428 +G+LGPVYG QWR + G DQ++ V+ ++ +PD RR+I+SAWN +L Sbjct: 90 QGELGPVYGVQWRSWPTP--------DGTHIDQISQVLQTLRTDPDSRRMIVSAWNVAEL 141 Query: 427 KKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPGE 248 +MAL PCH F QFYV +G+LSCQ+YQRSAD+ LGVPFNIASY+LLT M+AQ +L PGE Sbjct: 142 DRMALAPCHAFFQFYVADGKLSCQLYQRSADLFLGVPFNIASYALLTHMVAQQTELEPGE 201 Query: 247 FVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQKI 68 F+ GD H+Y HV+ + EQL ++P PFP L++ P D + D + Y H I Sbjct: 202 FIWTGGDCHIYDNHVEQVTEQLGREPYPFPRLELRPAPSLFD-YRFEDVTVTDYRHHPAI 260 Query: 67 EMKMAV 50 + +AV Sbjct: 261 KAPVAV 266
>TYSY_COXBU (Q83BG2) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 264 Score = 180 bits (456), Expect = 3e-45 Identities = 90/187 (48%), Positives = 120/187 (64%) Frame = -1 Query: 610 EEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTD 431 E GDLGP+YG QWR + G+ DQ+ +I +IK NPD RR+I+SAWN + Sbjct: 86 ENGDLGPIYGKQWRRWHCP--------DGRTVDQMQRLIREIKTNPDSRRLIVSAWNVGE 137 Query: 430 LKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPG 251 L +MALPPCH+ QFYV +G LSC++ QRSAD LGVPFNIASYSLLT +IA+ C+L G Sbjct: 138 LDQMALPPCHLLFQFYVADGFLSCKLTQRSADAFLGVPFNIASYSLLTHLIARQCNLKAG 197 Query: 250 EFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQK 71 EF+ GD H+Y+TH + QL ++P+ P L IN + + +DF + Y PH Sbjct: 198 EFIWSGGDCHIYNTHQDQVSTQLSREPRALPQLIINRDPSSLYDYNFNDFSIVNYHPHPA 257 Query: 70 IEMKMAV 50 I+ +AV Sbjct: 258 IKAPVAV 264
>TYSY_MYCTU (P67044) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 263 Score = 179 bits (454), Expect = 6e-45 Identities = 87/187 (46%), Positives = 124/187 (66%) Frame = -1 Query: 610 EEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTD 431 + G+LGP+YG QWR + A +G+ DQ++ ++ ++ +PD RRII+SAWN + Sbjct: 86 DTGELGPIYGVQWRSWPAP--------SGEHIDQISAALDLLRTDPDSRRIIVSAWNVGE 137 Query: 430 LKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPG 251 +++MALPPCH F QFYV +G LSCQ+YQRSAD+ LGVPFNIASY+LLT M+A LS G Sbjct: 138 IERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASYALLTHMMAAQAGLSVG 197 Query: 250 EFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQK 71 EF+ GD H+Y HV+ + QL ++P+P+P L + + I + D + YDPH Sbjct: 198 EFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLAD-RDSIFEYTYEDIVVKNYDPHPA 256 Query: 70 IEMKMAV 50 I+ +AV Sbjct: 257 IKAPVAV 263
>TYSY_MYCBO (P67045) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 263 Score = 179 bits (454), Expect = 6e-45 Identities = 87/187 (46%), Positives = 124/187 (66%) Frame = -1 Query: 610 EEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTD 431 + G+LGP+YG QWR + A +G+ DQ++ ++ ++ +PD RRII+SAWN + Sbjct: 86 DTGELGPIYGVQWRSWPAP--------SGEHIDQISAALDLLRTDPDSRRIIVSAWNVGE 137 Query: 430 LKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPG 251 +++MALPPCH F QFYV +G LSCQ+YQRSAD+ LGVPFNIASY+LLT M+A LS G Sbjct: 138 IERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASYALLTHMMAAQAGLSVG 197 Query: 250 EFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQK 71 EF+ GD H+Y HV+ + QL ++P+P+P L + + I + D + YDPH Sbjct: 198 EFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLAD-RDSIFEYTYEDIVVKNYDPHPA 256 Query: 70 IEMKMAV 50 I+ +AV Sbjct: 257 IKAPVAV 263
>TYSY_MYCPA (Q73VZ2) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 266 Score = 178 bits (451), Expect = 1e-44 Identities = 89/187 (47%), Positives = 122/187 (65%) Frame = -1 Query: 610 EEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTD 431 + GDLGP+YG QWR + +G+ DQ++ ++ ++ +PD RRII+SAWN + Sbjct: 89 DTGDLGPIYGVQWRSWPTP--------SGEHIDQISAALDLLRTDPDSRRIIVSAWNVGE 140 Query: 430 LKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPG 251 + +MALPPCH F QFYV +G LSCQ+YQRSAD+ LGVPFNIASY+LLT M+A LS G Sbjct: 141 IPRMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASYALLTHMMAAQAGLSVG 200 Query: 250 EFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQK 71 EFV GD H+Y HV+ + QL ++P+P+P L I + I + D + YDPH Sbjct: 201 EFVWTGGDCHIYDNHVEQVRLQLSREPRPYPEL-ILAHRDSIFDYTYDDVVVHNYDPHPA 259 Query: 70 IEMKMAV 50 I+ +AV Sbjct: 260 IKAPVAV 266
>TYSY_FRATT (Q5NFK5) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 274 Score = 178 bits (451), Expect = 1e-44 Identities = 91/199 (45%), Positives = 120/199 (60%), Gaps = 13/199 (6%) Frame = -1 Query: 607 EGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTDL 428 +G+LGP+YG QWR D+ G+G DQ+ADVI +K NP+ RRI++SAWNP + Sbjct: 87 DGELGPIYGKQWR-----------DFNGQGIDQIADVIQMLKTNPNSRRILVSAWNPCVV 135 Query: 427 KK-------------MALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLT 287 ALPPCH QFYV N +LSC + QRSAD LGVPFNIASYSLLT Sbjct: 136 PSEKISPQENVVKGNSALPPCHAMFQFYVANNKLSCMLTQRSADAFLGVPFNIASYSLLT 195 Query: 286 CMIAQVCDLSPGEFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVAS 107 M+AQ C+L GEF+ GD H+Y+ H++ + EQL ++P P LKI I + Sbjct: 196 NMVAQQCNLDVGEFIWSGGDCHIYNNHIEQVNEQLSREPLALPTLKILRKPNSIFDYKYE 255 Query: 106 DFKLACYDPHQKIEMKMAV 50 DF+ Y+ H I+ K++V Sbjct: 256 DFEFENYNHHPAIKAKISV 274
>TYSY_LACJO (Q74IU3) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 318 Score = 176 bits (446), Expect = 5e-44 Identities = 89/185 (48%), Positives = 116/185 (62%) Frame = -1 Query: 604 GDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTDLK 425 G+LG VYG QWRH+ G DQ+ +VI++IK P RR+I+SAWNP D+ Sbjct: 142 GNLGDVYGAQWRHWQKR--------EGGFIDQIQNVIDQIKKTPYSRRLIVSAWNPEDVP 193 Query: 424 KMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPGEF 245 ALPPCH+ QFYV +G LS Q+YQRS DM LGVPFNIASY+LL ++A+ L PGEF Sbjct: 194 TSALPPCHVLFQFYVNDGCLSLQLYQRSGDMFLGVPFNIASYALLVNLVARETGLKPGEF 253 Query: 244 VHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQKIE 65 +H +GDAH+Y H ++E L + P+L +NP KK + F D KL Y H I+ Sbjct: 254 IHTLGDAHIYKNHFNQVKELLNRSAYDAPMLWLNPDKKLVQDFEMKDIKLINYRHHGTIK 313 Query: 64 MKMAV 50 +AV Sbjct: 314 APVAV 318
>TYSY_MYCPU (Q98Q31) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 286 Score = 174 bits (440), Expect = 2e-43 Identities = 89/188 (47%), Positives = 122/188 (64%) Frame = -1 Query: 613 REEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPT 434 ++ G+LGPVYG QWR F G DQL VI +IKNNP+ RR+I+S+WNP+ Sbjct: 114 QKHGNLGPVYGKQWRDF-------------LGIDQLKKVIEQIKNNPNSRRLIVSSWNPS 160 Query: 433 DLKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSP 254 ++ M LPPCH QFYV + +LSC +YQRSAD LG+PFNIASY+LLT ++AQ +L Sbjct: 161 EIDTMLLPPCHTLFQFYVNDNKLSCHLYQRSADAFLGIPFNIASYALLTFLLAQETNLEV 220 Query: 253 GEFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQ 74 G+FVH IGDAH+Y H++ ++ QL++ PK P L I K+I D +L Y+ Sbjct: 221 GDFVHSIGDAHIYVNHLEQVKTQLKRNPKELPKLIIK--NKNIFEINFEDIELVDYEFDP 278 Query: 73 KIEMKMAV 50 I+ ++AV Sbjct: 279 IIKGEVAV 286
>TYSY_MYCLE (Q9CBW0) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 266 Score = 174 bits (440), Expect = 2e-43 Identities = 87/185 (47%), Positives = 117/185 (63%) Frame = -1 Query: 604 GDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTDLK 425 GDLGP+YG QWR + D DQ++ ++ ++ PD RRII+SAWN ++ Sbjct: 91 GDLGPIYGVQWRSWPTSSGDY--------IDQISTALDLLRTEPDSRRIIVSAWNVGEIP 142 Query: 424 KMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPGEF 245 +MALPPCH F QFYV G LSCQ+YQRSADM LGVPFNIASY+LLT M+A L GEF Sbjct: 143 QMALPPCHAFFQFYVAQGRLSCQLYQRSADMFLGVPFNIASYALLTHMMAAQSGLLVGEF 202 Query: 244 VHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQKIE 65 V GD H+Y HV+ ++ QL ++P+ +P L + + I +V D + YDPH I+ Sbjct: 203 VWTGGDCHIYDNHVEQVQLQLSREPRAYPELFL-AQRDSIFDYVYEDVVVTNYDPHPAIK 261 Query: 64 MKMAV 50 +A+ Sbjct: 262 APVAI 266
>TYSY_BUCAI (P57515) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 264 Score = 173 bits (438), Expect = 4e-43 Identities = 81/187 (43%), Positives = 121/187 (64%) Frame = -1 Query: 610 EEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTD 431 E GD+GP+YG QWR++ G DQ+ +V+ ++K NPD RR+++S+WN D Sbjct: 86 ESGDVGPIYGKQWRNWSTP--------EGHEIDQIKNVLIQLKKNPDSRRMLVSSWNVGD 137 Query: 430 LKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPG 251 + KM LPPCH+ QFYV N LSCQ+YQRS D+ LG+PFNIASYS+L MIAQ CDL G Sbjct: 138 IDKMRLPPCHVLFQFYVFNNTLSCQLYQRSCDVFLGLPFNIASYSILIHMIAQQCDLKVG 197 Query: 250 EFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQK 71 +F+ GD H+Y+ H++ ++Q+ + P+ P L I + + + DFK+ Y P+ Sbjct: 198 DFLWTGGDVHLYNNHIELAKKQILRIPRTLPKLTILKKPQSLFQYCFEDFKIIGYHPYPA 257 Query: 70 IEMKMAV 50 I+ ++++ Sbjct: 258 IKGEISI 264
>TYSY_MESFL (Q6F145) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 288 Score = 173 bits (438), Expect = 4e-43 Identities = 92/186 (49%), Positives = 118/186 (63%), Gaps = 1/186 (0%) Frame = -1 Query: 604 GDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTDLK 425 GDLGPVYG QWR FG G DQ A +IN IK NP RR I+SAWNP ++ Sbjct: 117 GDLGPVYGKQWRDFG-------------GIDQFAKLINDIKKNPFSRRHIVSAWNPAEVD 163 Query: 424 KMALPPCHMFAQFYV-ENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPGE 248 M LPPCH F Q YV ++G L Q+YQRS D+ LGVPFNIASY+LL +IA+ C+L Sbjct: 164 NMLLPPCHSFWQVYVSKDGWLDLQLYQRSGDVFLGVPFNIASYALLMELIAKECNLKARY 223 Query: 247 FVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQKI 68 FVH IGDAH+Y H++ + EQL+++P P +KIN +K I D ++ Y+ H KI Sbjct: 224 FVHTIGDAHIYLNHLEQINEQLKRKPLPLCKIKINS-EKSIFDIAFEDIEIEGYESHAKI 282 Query: 67 EMKMAV 50 ++AV Sbjct: 283 TGEVAV 288
>TYSY_BUCBP (P59427) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 264 Score = 171 bits (433), Expect = 2e-42 Identities = 87/187 (46%), Positives = 119/187 (63%) Frame = -1 Query: 610 EEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTD 431 E G LGP+YG QWR + + G+ DQ+ +VI+ IKNNP+ RRI++S+WN D Sbjct: 86 ERGYLGPIYGEQWRSWKTK--------DGRVIDQIDNVIHLIKNNPNSRRIVVSSWNVGD 137 Query: 430 LKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPG 251 L KMAL PCH+ QF+V + L CQ+YQRS D+ LG+PFNIASYSLLT MIAQ C+L G Sbjct: 138 LHKMALLPCHVLFQFHVVDHVLHCQLYQRSCDVFLGLPFNIASYSLLTHMIAQQCNLKVG 197 Query: 250 EFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQK 71 F+ GD H+Y H++ ++Q+ ++P P L IN I +++ DF L Y H Sbjct: 198 NFIWTGGDVHLYKNHIKQAKKQILRRPYLLPKLVINRKPTQIFNYLLQDFNLLNYKYHPS 257 Query: 70 IEMKMAV 50 I K+A+ Sbjct: 258 IHAKIAI 264
>TYSY_BUCAP (Q8K9C3) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 264 Score = 169 bits (429), Expect = 4e-42 Identities = 83/185 (44%), Positives = 119/185 (64%) Frame = -1 Query: 604 GDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTDLK 425 GDLGP+YG QWR + GK DQ+ +V+ +IK +PD RRI++S+WN ++ Sbjct: 88 GDLGPIYGKQWRSWDTS--------NGKKIDQIKNVLKQIKEDPDSRRILVSSWNVGEID 139 Query: 424 KMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPGEF 245 KM+L PCH+ QFYV +LSCQ+YQRS D+ LG+PFNIASY++L MIAQ C+L GEF Sbjct: 140 KMSLAPCHILFQFYVLKKKLSCQLYQRSCDVFLGLPFNIASYAILIHMIAQQCNLQVGEF 199 Query: 244 VHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQKIE 65 + GD H+Y HV+ ++Q+ + PK P L I + + + DFK+ Y P+ I+ Sbjct: 200 LWTGGDVHLYKNHVELAKKQILRIPKKLPELIILKKPQSLFQYSFEDFKIVGYKPYSLIK 259 Query: 64 MKMAV 50 K++V Sbjct: 260 GKISV 264
>TYSY_MYCGE (P47469) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 287 Score = 166 bits (420), Expect = 5e-41 Identities = 87/190 (45%), Positives = 120/190 (63%), Gaps = 2/190 (1%) Frame = -1 Query: 613 REEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPT 434 ++ DLGPVYG QWR+F G DQL VI +IK NP+ RR+I+S+WNP+ Sbjct: 114 KQFADLGPVYGKQWRNFN-------------GVDQLKKVIQEIKENPNSRRLIVSSWNPS 160 Query: 433 DLKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSP 254 +L+KMAL PCH QFYVE +LS Q+YQRS D+ LGVPFNIASY+LL ++A L P Sbjct: 161 ELEKMALAPCHSLFQFYVEEDKLSLQLYQRSGDIFLGVPFNIASYALLVYLVAHETKLKP 220 Query: 253 GEFVHVIGDAHVYSTHVQALEEQLQKQ--PKPFPILKINPLKKDIDSFVASDFKLACYDP 80 G F+H +GDAH+Y H++ ++ QL + P +LK + K I ++ D +L Y+ Sbjct: 221 GYFIHTLGDAHIYENHIEQIKLQLTRTTLDPPQVVLKSD---KSIFAYSFDDIELVGYNY 277 Query: 79 HQKIEMKMAV 50 H I ++AV Sbjct: 278 HPFIYGRVAV 287
>TYSY_BPT4 (P00471) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 286 Score = 163 bits (413), Expect = 3e-40 Identities = 89/197 (45%), Positives = 118/197 (59%), Gaps = 12/197 (6%) Frame = -1 Query: 604 GDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTDLK 425 G+LGP+YG QWR FG G DQ+ +VI++IK P+DRR I+SAWNP +LK Sbjct: 103 GELGPIYGKQWRDFG-------------GVDQIIEVIDRIKKLPNDRRQIVSAWNPAELK 149 Query: 424 KMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPGEF 245 MALPPCHMF QF V NG L Q YQRS D+ LG+PFNIASY+ L ++A++C+L PG+ Sbjct: 150 YMALPPCHMFYQFNVRNGYLDLQWYQRSVDVFLGLPFNIASYATLVHIVAKMCNLIPGDL 209 Query: 244 VHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLK------------KDIDSFVASDF 101 + G+ H+Y HV+ +E L+++PK L I+ L K + DF Sbjct: 210 IFSGGNTHIYMNHVEQCKEILRREPKELCELVISGLPYKFRYLSTKEQLKYVLKLRPKDF 269 Query: 100 KLACYDPHQKIEMKMAV 50 L Y H I+ KMAV Sbjct: 270 VLNNYVSHPPIKGKMAV 286
>DRTS_MIMIV (Q5UQG3) Bifunctional dihydrofolate reductase-thymidylate synthase| (DHFR-TS) [Includes: Dihydrofolate reductase (EC 1.5.1.3); Thymidylate synthase (EC 2.1.1.45)] Length = 563 Score = 160 bits (406), Expect = 2e-39 Identities = 87/197 (44%), Positives = 117/197 (59%), Gaps = 12/197 (6%) Frame = -1 Query: 610 EEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTD 431 EEGD+GP YGFQ R++GAEY+D Y G+G DQL I I+NNP DRRI+++ WN +D Sbjct: 367 EEGDIGPGYGFQMRYWGAEYTDCKTSYQGQGIDQLNKCIESIQNNPHDRRIMINLWNCSD 426 Query: 430 LKKMALPPCHMFAQFYVE----------NGELSCQMYQRSADMGLGVPFNIASYSLLTCM 281 L KMAL PCH F V+ G L+C + QRS D+ LG +N + +LLT + Sbjct: 427 LDKMALAPCHFCYMFGVDLYEVPTTSGKKGRLNCHLVQRSWDVLLG--WNTTTAALLTYL 484 Query: 280 IAQVCDLSPGEFVHVIGDAHVYSTHVQ--ALEEQLQKQPKPFPILKINPLKKDIDSFVAS 107 IA CDL PG VH I DAH+Y +H+ A+ + LQ++ + FP L I K+ ID + Sbjct: 485 IANHCDLDPGILVHSISDAHIYQSHIDSGAISQLLQRKCRKFPNLVIRNKKEKIDDYEFD 544 Query: 106 DFKLACYDPHQKIEMKM 56 D + Y P I +M Sbjct: 545 DLIIENYYPCPSISAEM 561
>TYSY_SYMTH (Q67JQ1) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 283 Score = 157 bits (396), Expect = 3e-38 Identities = 83/196 (42%), Positives = 120/196 (61%), Gaps = 9/196 (4%) Frame = -1 Query: 613 REEGDLGPVYGFQWRHF-GAEYSDMHADYTGKGFDQLADVINKIKN--------NPDDRR 461 R G LGP+YG QWR + GA+ G+ +DQ+A VI +I+ +P+ RR Sbjct: 96 RNGGKLGPIYGKQWRAWEGAD---------GRTYDQIAWVIQQIREIAADPERPHPNSRR 146 Query: 460 IILSAWNPTDLKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCM 281 +++S WN DL++MALPPCH QF+V++G L ++QRSAD+ LGVPFNIASYSLL M Sbjct: 147 LVVSPWNVADLEEMALPPCHGPFQFHVKDGRLHLAVWQRSADLFLGVPFNIASYSLLLHM 206 Query: 280 IAQVCDLSPGEFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDF 101 +AQV L+ G + H + D H+Y + + QL ++P P P L +NP ++ID F D Sbjct: 207 VAQVTGLAVGTYTHYLNDVHIYRNLLDQVRLQLTREPYPLPRLWLNPEVREIDQFTMDDI 266 Query: 100 KLACYDPHQKIEMKMA 53 +L Y H I +++ Sbjct: 267 QLVDYKHHPPIRGELS 282
>TYSY_ZYMMO (Q9Z671) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 296 Score = 155 bits (393), Expect = 7e-38 Identities = 78/186 (41%), Positives = 114/186 (61%), Gaps = 1/186 (0%) Frame = -1 Query: 604 GDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTDLK 425 GDLGPVYG QWR + + SD G+ +DQ+A +I +K+NP RR++ WN +LK Sbjct: 119 GDLGPVYGRQWRRW--QGSD------GQVYDQIATLIETLKSNPSSRRMLFHGWNVAELK 170 Query: 424 KMALPPCHMFAQFYV-ENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPGE 248 MALPPCHM Q++V +G L+ +YQRSAD+ LG+PFN+ + L M+A L+ G+ Sbjct: 171 DMALPPCHMVYQYHVTSDGRLNSLLYQRSADVFLGLPFNLVGAAALQAMLADQAGLALGD 230 Query: 247 FVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQKI 68 V GD H+Y H+ ++EQL ++P+ FP L++ I + DF + YDPH I Sbjct: 231 LVWTGGDVHIYRNHIDQMKEQLAREPRAFPRLELTRHPNSITDYKIEDFAITGYDPHPPI 290 Query: 67 EMKMAV 50 + +AV Sbjct: 291 KGAVAV 296
>TYSY_WIGBR (Q8D2N4) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 264 Score = 155 bits (391), Expect = 1e-37 Identities = 75/187 (40%), Positives = 112/187 (59%) Frame = -1 Query: 610 EEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTD 431 + G+LGP+YG QWR + D DQ+ +NK+K P RRI++S+WN + Sbjct: 86 KNGNLGPIYGKQWRAW--------EDKKNNTIDQIEIALNKLKKEPSSRRILVSSWNVGE 137 Query: 430 LKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPG 251 L M++PPCH+ Q YV N +LSCQ+YQRS D+ LG+PFNI SY+LLT + A CDL Sbjct: 138 LDLMSIPPCHVLFQLYVINNKLSCQVYQRSCDIFLGLPFNIGSYALLTHIFANQCDLLVE 197 Query: 250 EFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQK 71 + + GD H+Y H+ + QL + P P P + I K++ ++ +DF L Y+ H K Sbjct: 198 DLIWTGGDIHLYKNHLNQAKLQLTRSPLPLPKIFIKKKPKNLFNYAFNDFLLIDYNHHPK 257 Query: 70 IEMKMAV 50 I+ +++ Sbjct: 258 IKAPISI 264
>TYSY_METCA (Q603S2) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 260 Score = 151 bits (382), Expect = 1e-36 Identities = 77/187 (41%), Positives = 108/187 (57%) Frame = -1 Query: 610 EEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTD 431 + G+LGPVYG QWR++ DQLA ++ +++ NP RR+++SAWNP+D Sbjct: 86 DNGELGPVYGRQWRNWNG------------AIDQLAGLVEQLRRNPGSRRLLVSAWNPSD 133 Query: 430 LKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPG 251 L MALPPCH Q +V +G LS RSAD+ LG+PFNIA Y+LLT M+AQ PG Sbjct: 134 LDAMALPPCHYAFQCHVADGRLSLMFQMRSADVFLGLPFNIAGYALLTHMLAQQTGYEPG 193 Query: 250 EFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQK 71 E + GD H+Y H++ QL ++P P P LK+ + + DF + Y H Sbjct: 194 ELIWCGGDVHLYLNHLEQARLQLTREPYPPPTLKLARKPGSLFDYRYEDFVVEDYQAHPH 253 Query: 70 IEMKMAV 50 I+ +AV Sbjct: 254 IKAAVAV 260
>TYSY_CLOAB (Q97EV3) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 263 Score = 144 bits (364), Expect = 2e-34 Identities = 76/189 (40%), Positives = 112/189 (59%), Gaps = 2/189 (1%) Frame = -1 Query: 610 EEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTD 431 E+G +G YG+Q F Q+ ++I+ +K +P RR+++S WN D Sbjct: 91 EDGTIGKAYGYQVAKF----------------KQIDNLIDTLKTDPQSRRMLISLWNIAD 134 Query: 430 LKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPG 251 LK M+L PC + V+NG+L+C + QRS DM LGVPFN+ Y++L +IAQV L PG Sbjct: 135 LKDMSLTPCCYETLWDVQNGKLNCMLVQRSGDMPLGVPFNMCQYAVLVHLIAQVTGLKPG 194 Query: 250 EFVHVIGDAHVYSTHVQALEEQLQKQPKPF--PILKINPLKKDIDSFVASDFKLACYDPH 77 F HVI +AH+Y ++ ++ QL+++ K + P L INP K+ F A D KL Y H Sbjct: 195 LFTHVINNAHIYKNQIEGMKIQLKRRDKAYEAPKLWINPNIKNFYDFTADDIKLIDYKHH 254 Query: 76 QKIEMKMAV 50 KI+M++AV Sbjct: 255 DKIKMEVAV 263
>TYSY_BPPHT (P07606) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 279 Score = 139 bits (350), Expect = 6e-33 Identities = 75/188 (39%), Positives = 107/188 (56%) Frame = -1 Query: 613 REEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPT 434 +E+G +G YGFQ + G+ DQ+ +++++KNNP RR I WNP Sbjct: 99 QEDGTIGHAYGFQ-------LGKKNRSLNGEKVDQVDYLLHQLKNNPSSRRHITMLWNPD 151 Query: 433 DLKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSP 254 DL MAL PC Q+YV+ G+L ++ RS DM LG PFN+ Y++L MIAQV Sbjct: 152 DLDAMALTPCVYETQWYVKQGKLHLEVRARSNDMALGNPFNVFQYNVLQRMIAQVTGYEL 211 Query: 253 GEFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQ 74 GE++ IGD HVY+ H+ L+ Q++++ P L INP KD +F DFKL Y Sbjct: 212 GEYIFNIGDCHVYTRHIDNLKIQMEREQFEAPELWINPEVKDFYNFTVDDFKLINYKHGD 271 Query: 73 KIEMKMAV 50 K+ ++AV Sbjct: 272 KLLFEVAV 279
>TYSY_BACMO (Q9ANR7) Thymidylate synthase A (EC 2.1.1.45) (TS A) (TSase A)| Length = 279 Score = 138 bits (348), Expect = 1e-32 Identities = 73/188 (38%), Positives = 108/188 (57%) Frame = -1 Query: 613 REEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPT 434 +E+G +G YGFQ + + + G+ DQ+ +++++KNNP RR I WNP Sbjct: 99 QEDGSIGHAYGFQ-------LAKKNRNLNGEKVDQVDYLLHQLKNNPSSRRHITMLWNPD 151 Query: 433 DLKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSP 254 +L MAL PC Q+YV+ G+L ++ RS DM LG PFN+ Y++L MIAQV Sbjct: 152 ELDSMALTPCVYETQWYVKQGKLHLEVRARSNDMALGNPFNVFQYNVLQRMIAQVTGYEL 211 Query: 253 GEFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQ 74 GE++ IGD HVY+ H+ L+ Q++++ P L INP KD F DFKL Y Sbjct: 212 GEYIFNIGDCHVYTRHIDNLKIQMEREQFEAPKLWINPEVKDFYDFTIDDFKLINYKHGD 271 Query: 73 KIEMKMAV 50 ++ ++AV Sbjct: 272 RLSFEVAV 279
>TYSY_BACNA (Q5D189) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 279 Score = 138 bits (347), Expect = 1e-32 Identities = 74/188 (39%), Positives = 108/188 (57%) Frame = -1 Query: 613 REEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPT 434 +E+G +G YGFQ + G+ DQ+ +++++KNNP RR I WNP Sbjct: 99 QEDGTIGHAYGFQ-------LGKKNRSLNGEKVDQVDYLLHQLKNNPSSRRHITMLWNPD 151 Query: 433 DLKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSP 254 DL M+L PC Q+YV++G+L ++ RS DM LG PFN+ Y++L MIAQV Sbjct: 152 DLDAMSLTPCVYETQWYVKHGKLHLEVRARSNDMALGNPFNVFQYNVLQRMIAQVTGYEL 211 Query: 253 GEFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQ 74 GE++ IGD HVY+ H+ L+ Q++++ P L INP KD +F DFKL Y Sbjct: 212 GEYIFNIGDCHVYTRHIDNLKIQMEREQFEAPELWINPEVKDFYNFTIDDFKLINYKHGD 271 Query: 73 KIEMKMAV 50 K+ ++AV Sbjct: 272 KLLFEVAV 279
>TYSA_BACSU (P42326) Thymidylate synthase A (EC 2.1.1.45) (TS A) (TSase A)| Length = 279 Score = 137 bits (345), Expect = 2e-32 Identities = 74/188 (39%), Positives = 107/188 (56%) Frame = -1 Query: 613 REEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPT 434 +E+G +G YGFQ + G+ DQ+ +++++KNNP RR I WNP Sbjct: 99 QEDGTIGHAYGFQ-------LGKKNRSLNGEKVDQVDYLLHQLKNNPSSRRHITMLWNPD 151 Query: 433 DLKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSP 254 +L MAL PC Q+YV++G+L ++ RS DM LG PFN+ Y++L MIAQV Sbjct: 152 ELDAMALTPCVYETQWYVKHGKLHLEVRARSNDMALGNPFNVFQYNVLQRMIAQVTGYEL 211 Query: 253 GEFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQ 74 GE++ IGD HVY+ H+ L+ Q++++ P L INP KD F DFKL Y Sbjct: 212 GEYIFNIGDCHVYTRHIDNLKIQMEREQFEAPELWINPEVKDFYDFTIDDFKLINYKHGD 271 Query: 73 KIEMKMAV 50 K+ ++AV Sbjct: 272 KLLFEVAV 279
>TYSA_BACAM (O30397) Thymidylate synthase A (EC 2.1.1.45) (TS A) (TSase A)| (Fragment) Length = 230 Score = 135 bits (340), Expect = 9e-32 Identities = 73/188 (38%), Positives = 106/188 (56%) Frame = -1 Query: 613 REEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPT 434 +E+G +G YGFQ + G+ DQ+ +++++KNNP RR I WNP Sbjct: 50 QEDGTIGHAYGFQ-------LGKKNRSLNGEKVDQVDYLLHQLKNNPSSRRHITMLWNPD 102 Query: 433 DLKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSP 254 +L MAL PC Q+YV++G+L ++ RS DM LG PFN+ Y++L MIAQV Sbjct: 103 ELDAMALTPCVYETQWYVKHGKLHLEVRARSNDMALGNPFNVFQYNVLQRMIAQVTGYEL 162 Query: 253 GEFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQ 74 GE++ IGD HVY+ H+ L+ Q++++ P L INP KD F DFKL Y Sbjct: 163 GEYIFNIGDCHVYTRHIDNLKIQMEREQFEAPELWINPEVKDFYDFTIDDFKLINYKHGD 222 Query: 73 KIEMKMAV 50 K+ ++ V Sbjct: 223 KLLFEVPV 230
>TYSA_BACAT (O30394) Thymidylate synthase A (EC 2.1.1.45) (TS A) (TSase A)| (Fragment) Length = 227 Score = 135 bits (340), Expect = 9e-32 Identities = 73/188 (38%), Positives = 106/188 (56%) Frame = -1 Query: 613 REEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPT 434 +E+G +G YGFQ + G+ DQ+ +++++KNNP RR I WNP Sbjct: 47 QEDGTIGHAYGFQ-------LGKKNRSLNGEKVDQVDYLLHQLKNNPSSRRHITMLWNPD 99 Query: 433 DLKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSP 254 +L MAL PC Q+YV++G+L ++ RS DM LG PFN+ Y++L MIAQV Sbjct: 100 ELDAMALTPCVYETQWYVKHGKLHLEVRARSNDMALGNPFNVFQYNVLQRMIAQVTGYEL 159 Query: 253 GEFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQ 74 GE++ IGD HVY+ H+ L+ Q++++ P L INP KD F DFKL Y Sbjct: 160 GEYIFNIGDCHVYTRHIDNLKIQMEREQFEAPELWINPEVKDFYDFTIDDFKLINYKHGD 219 Query: 73 KIEMKMAV 50 K+ ++ V Sbjct: 220 KLLFEVRV 227
>TYSY_BACLD (Q65J44) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 279 Score = 133 bits (334), Expect = 5e-31 Identities = 71/187 (37%), Positives = 105/187 (56%) Frame = -1 Query: 610 EEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTD 431 E+G +G YG+Q + G+ DQ+ +++++K+NP RR + WNP D Sbjct: 100 EDGTIGAAYGYQ-------LGKKNRTVNGQKVDQVDYLLHQLKHNPSSRRHLTMLWNPDD 152 Query: 430 LKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPG 251 L MAL PC Q+YV+ G+LS ++ RS DM LG PFN+ Y++L MIAQV G Sbjct: 153 LDGMALTPCVYETQWYVKEGKLSLEVRARSNDMALGNPFNVFQYNVLQRMIAQVLGYELG 212 Query: 250 EFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQK 71 E++ IGD H+Y+ H+ L Q++++ P L INP K+ F DFKL Y K Sbjct: 213 EYIFNIGDCHIYTRHIDNLNIQMKREQYEAPKLWINPDIKNFYDFTIDDFKLIDYKHGDK 272 Query: 70 IEMKMAV 50 + ++AV Sbjct: 273 LTFEVAV 279
>TYSA_BACLI (Q59212) Thymidylate synthase A (EC 2.1.1.45) (TS A) (TSase A)| Length = 279 Score = 133 bits (334), Expect = 5e-31 Identities = 71/187 (37%), Positives = 105/187 (56%) Frame = -1 Query: 610 EEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTD 431 E+G +G YG+Q + G+ DQ+ +++++K+NP RR + WNP D Sbjct: 100 EDGTIGAAYGYQ-------LGKKNRTVNGQKVDQVDYLLHQLKHNPSSRRHLTMLWNPDD 152 Query: 430 LKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPG 251 L MAL PC Q+YV+ G+LS ++ RS DM LG PFN+ Y++L MIAQV G Sbjct: 153 LDGMALTPCVYETQWYVKEGKLSLEVRARSNDMALGNPFNVFQYNVLQRMIAQVLGYELG 212 Query: 250 EFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQK 71 E++ IGD H+Y+ H+ L Q++++ P L INP K+ F DFKL Y K Sbjct: 213 EYIFNIGDCHIYTRHIDNLNIQMKREQYEAPKLWINPDIKNFYDFTIDDFKLIDYKHGDK 272 Query: 70 IEMKMAV 50 + ++AV Sbjct: 273 LTFEVAV 279
>TYSY_BORPE (Q7VUE3) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 323 Score = 127 bits (318), Expect = 3e-29 Identities = 78/223 (34%), Positives = 109/223 (48%), Gaps = 39/223 (17%) Frame = -1 Query: 601 DLGPVYGFQWRHF----------GAEYSDMHA---------DYTG-------KGFDQLAD 500 DLGPVYG QWRH+ G + +D A D G K DQL Sbjct: 101 DLGPVYGVQWRHWPAYKLLPSSAGGQVADALARGYRQVAEVDENGAPHVLLYKAVDQLRQ 160 Query: 499 VINKIKNNPDDRRIILSAWNPTDLKKMALPPCHMFAQFYVENG--ELSCQMYQRSADMGL 326 ++ I+ +P DRRI+ WN +++MALPPCH+ QF G E+S +Y RS D+GL Sbjct: 161 CLDTIRQSPGDRRILFHGWNWAQIEEMALPPCHLLYQFLPNAGTREISLCLYIRSNDVGL 220 Query: 325 GVPFNIASYSLLTCMIAQVCDLSPGEFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKI 146 G PFN+ + L ++ ++ P F + IGDAHVY H+ L EQL ++P P P L + Sbjct: 221 GTPFNLTEGAALLHLVGRLTGYKPRWFSYFIGDAHVYENHLPMLREQLAREPYPAPQLVL 280 Query: 145 NPLKKD-----------IDSFVASDFKLACYDPHQKIEMKMAV 50 + D ++ DF L+ Y H + MAV Sbjct: 281 SDRIPDFAVTGKYEPQWLEQVEPGDFTLSGYQHHAPLTAPMAV 323
>TYSY_BORPA (Q7W1A9) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 323 Score = 125 bits (313), Expect = 1e-28 Identities = 76/223 (34%), Positives = 108/223 (48%), Gaps = 39/223 (17%) Frame = -1 Query: 601 DLGPVYGFQWRHFGA------EYSDMHADYTGKGFDQLADV------------------- 497 DLGPVYG QWRH+ A AD +G+ Q+A+V Sbjct: 101 DLGPVYGVQWRHWPAYKLLPRSAGGQVADALARGYRQVAEVAENGAPHVLLYKAVDQLRQ 160 Query: 496 -INKIKNNPDDRRIILSAWNPTDLKKMALPPCHMFAQFYVENG--ELSCQMYQRSADMGL 326 ++ I +P DRRI+ WN +++MALPPCH+ QF G E+S +Y RS D+GL Sbjct: 161 CLDTIHQSPGDRRILFHGWNWAQIEEMALPPCHLLYQFLPNAGTREISLCLYIRSNDVGL 220 Query: 325 GVPFNIASYSLLTCMIAQVCDLSPGEFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKI 146 G PFN+ + L ++ ++ P F + IGDAHVY H+ L EQL ++P P P L + Sbjct: 221 GTPFNLTEGAALLHLVGRLTGYKPRWFSYFIGDAHVYENHLPMLREQLTREPYPAPQLVL 280 Query: 145 NPLKKD-----------IDSFVASDFKLACYDPHQKIEMKMAV 50 + D ++ DF L+ Y H + MAV Sbjct: 281 SDRIPDFAVTGKYEPQWLEQVEPGDFTLSGYQHHAPLTAPMAV 323
>TYSY_BORBR (Q7WP13) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 323 Score = 125 bits (313), Expect = 1e-28 Identities = 76/223 (34%), Positives = 108/223 (48%), Gaps = 39/223 (17%) Frame = -1 Query: 601 DLGPVYGFQWRHFGA------EYSDMHADYTGKGFDQLADV------------------- 497 DLGPVYG QWRH+ A AD +G+ Q+A+V Sbjct: 101 DLGPVYGVQWRHWPAYKLLPRSAGGQVADALARGYRQVAEVAENGAPHVLLYKAVDQLRQ 160 Query: 496 -INKIKNNPDDRRIILSAWNPTDLKKMALPPCHMFAQFYVENG--ELSCQMYQRSADMGL 326 ++ I +P DRRI+ WN +++MALPPCH+ QF G E+S +Y RS D+GL Sbjct: 161 CLDTIHQSPGDRRILFHGWNWAQIEEMALPPCHLLYQFLPNAGTREISLCLYIRSNDVGL 220 Query: 325 GVPFNIASYSLLTCMIAQVCDLSPGEFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKI 146 G PFN+ + L ++ ++ P F + IGDAHVY H+ L EQL ++P P P L + Sbjct: 221 GTPFNLTEGAALLHLVGRLTGYKPRWFSYFIGDAHVYENHLPMLREQLTREPYPAPQLVL 280 Query: 145 NPLKKD-----------IDSFVASDFKLACYDPHQKIEMKMAV 50 + D ++ DF L+ Y H + MAV Sbjct: 281 SDRIPDFAVTGKYEPQWLEQVEPGDFTLSGYQHHAPLTAPMAV 323
>TYSY_PSESM (Q87UL4) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 323 Score = 119 bits (298), Expect = 7e-27 Identities = 74/225 (32%), Positives = 107/225 (47%), Gaps = 39/225 (17%) Frame = -1 Query: 607 EGDLGPVYGFQWRHF------------------GAEYSDM-HADYTGKGF-------DQL 506 E DLG +YG QWR + G Y + ++ G+ F DQ+ Sbjct: 99 EDDLGEIYGVQWRKWPAYKRIDTGNVAAIELALGQGYRQIAESEEDGQSFVVLYKAIDQI 158 Query: 505 ADVINKIKNNPDDRRIILSAWNPTDLKKMALPPCHMFAQFY--VENGELSCQMYQRSADM 332 I+ I N+P RRI+ WN L +MALPPCH+ Q + + E+S +Y RS D+ Sbjct: 159 RQCIDTIINDPGSRRILFHGWNCAQLDEMALPPCHLLYQLHPNPQTREISLTLYIRSNDL 218 Query: 331 GLGVPFNIASYSLLTCMIAQVCDLSPGEFVHVIGDAHVYSTHVQALEEQLQKQPKPFPIL 152 GLG PFN+ + L +I ++ +P F + IGDAHVY H+ L EQ+ ++P P P L Sbjct: 219 GLGTPFNLTEGAALLSLIGRLTGYTPRWFTYFIGDAHVYENHLDMLNEQMTREPYPMPKL 278 Query: 151 KINPLKKD-----------IDSFVASDFKLACYDPHQKIEMKMAV 50 I+ + ++ SDF L Y H + MAV Sbjct: 279 VISDRVPEFAKTGVYQPEWLELIEPSDFSLEGYQHHPAMTAPMAV 323
>TYSY_PSEPK (Q88CN9) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 323 Score = 116 bits (291), Expect = 5e-26 Identities = 74/223 (33%), Positives = 107/223 (47%), Gaps = 39/223 (17%) Frame = -1 Query: 601 DLGPVYGFQWRHF-GAEYSDMH-------ADYTG------------------KGFDQLAD 500 DLG +YG QWR + G + + A+ G K DQ+ Sbjct: 101 DLGEIYGVQWRQWPGYKRIPLSNPAAIEMAEQAGFRRIAQDEEDGVAFVILYKAIDQVRQ 160 Query: 499 VINKIKNNPDDRRIILSAWNPTDLKKMALPPCHMFAQFY--VENGELSCQMYQRSADMGL 326 ++ I N+P RRI+ WN L +MALPPCH+ QF+ VE E+S +Y RS D+GL Sbjct: 161 CLDTIANDPGSRRILFHGWNCAQLDEMALPPCHLLYQFHPNVETREISLTLYIRSNDLGL 220 Query: 325 GVPFNIASYSLLTCMIAQVCDLSPGEFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKI 146 G PFN+ + L + ++ +P F + IGDAHVY H+ L EQL+++P P L I Sbjct: 221 GTPFNLTEGAALLSLFGRLTGYTPRWFTYFIGDAHVYENHLDMLNEQLKREPLEAPKLVI 280 Query: 145 NPL-----------KKDIDSFVASDFKLACYDPHQKIEMKMAV 50 + + ++ SDF L Y+ H + MAV Sbjct: 281 SDRVPAFAETGKYEPEWLEKIEPSDFWLEGYEHHAPMTAPMAV 323
>TYSY_FUSNN (Q8RGP6) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 275 Score = 102 bits (254), Expect = 9e-22 Identities = 61/187 (32%), Positives = 95/187 (50%) Frame = -1 Query: 610 EEGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTD 431 ++G +G YG+Q A T QL VIN++K NP+ RRI+ W P + Sbjct: 101 QDGTIGKAYGYQI-----------AQETFGQKSQLHYVINELKKNPNSRRIMTEIWIPNE 149 Query: 430 LKKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPG 251 L +MAL PC Q+ V +L ++ QRS D+ LG+ N+ YS+L ++A C L P Sbjct: 150 LSEMALTPCVHLTQWSVIGNKLYLEVRQRSCDVALGLVANVFQYSVLHKLVALECGLEPA 209 Query: 250 EFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQK 71 E + I + H+Y H L EQ+ ++ +KIN K D F D ++ Y +K Sbjct: 210 EIIWNIHNMHIYDRHYDKLIEQVNRETFEPAKIKINNFKSIFD-FKPDDIEIIDYKYGEK 268 Query: 70 IEMKMAV 50 + ++A+ Sbjct: 269 VSYEVAI 275
>TYSY_IDILO (Q5R064) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 283 Score = 96.7 bits (239), Expect = 5e-20 Identities = 65/191 (34%), Positives = 96/191 (50%), Gaps = 5/191 (2%) Frame = -1 Query: 607 EGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTDL 428 E D+G VYG Q R + G DQL VIN + DDR I++ +NP + Sbjct: 101 EDDMGRVYGVQGRSWQKP--------DGSHLDQLKKVINNLSKGIDDRGEIVTFYNPGEF 152 Query: 427 KKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPGE 248 + L PC F + L YQRS D+ LG+ FN L ++AQ+ PG+ Sbjct: 153 ELGCLRPCMHTHNFSLLGDTLYLTSYQRSCDVPLGLNFNQIQCFALLALVAQITGHKPGK 212 Query: 247 FVHVIGDAHVYSTHVQALEE-QLQKQPKPFPILKINPLKK---DIDSFVA-SDFKLACYD 83 H I +AH+Y ++ + + QL+++P P P L INP K DI+++V+ DF ++ Y Sbjct: 213 AYHKIVNAHIYENQLELMRDVQLKREPFPSPQLHINPEIKSLEDIETWVSKDDFIVSGYQ 272 Query: 82 PHQKIEMKMAV 50 H I+ AV Sbjct: 273 CHDPIKYPFAV 283
>TYSY_VIBF1 (Q5E7P1) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 283 Score = 92.8 bits (229), Expect = 7e-19 Identities = 60/191 (31%), Positives = 97/191 (50%), Gaps = 5/191 (2%) Frame = -1 Query: 607 EGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTDL 428 + D+G VYG Q R + A G+ DQL +I+ + DDR IL+ +NP + Sbjct: 101 DDDMGRVYGVQGRSW--------AKPNGEFVDQLKKIIDDLSQGIDDRGEILNFYNPGEF 152 Query: 427 KKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPGE 248 L PC F + L QRS D+ LG+ FN+ L ++AQ+ G+ Sbjct: 153 DMGCLRPCMYSHHFSLLGDTLYLNSTQRSCDVPLGLNFNMVQVYFLLAIVAQITGHKAGK 212 Query: 247 FVHVIGDAHVYSTHVQALEE-QLQKQPKPFPILKINPLKK---DIDSFVA-SDFKLACYD 83 H I +AH+Y ++ ++ QL+++P PI KINP K D++++V DF++ Y+ Sbjct: 213 AYHKIVNAHIYEDQLELMQSVQLKREPLQAPIFKINPEIKSLEDLETWVTMDDFEVIGYE 272 Query: 82 PHQKIEMKMAV 50 H+ I+ +V Sbjct: 273 SHEAIKYPFSV 283
>TYSY_HAEIN (P44420) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 283 Score = 92.8 bits (229), Expect = 7e-19 Identities = 59/189 (31%), Positives = 94/189 (49%), Gaps = 5/189 (2%) Frame = -1 Query: 601 DLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTDLKK 422 D+G VYG Q R + G+ DQL ++N + DDR IL+ +NP + Sbjct: 103 DMGRVYGVQGRAWRKP--------NGETIDQLRKIVNNLTKGIDDRGEILTFFNPGEFDL 154 Query: 421 MALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPGEFV 242 L PC F + L YQRS D+ LG+ FN ++AQ+ G+ Sbjct: 155 GCLRPCMHTHTFSLVGDTLHLTSYQRSCDVPLGLNFNQIQVFTFLALMAQITGKKAGKAY 214 Query: 241 HVIGDAHVYSTHVQALEE-QLQKQPKPFPILKINP---LKKDIDSFVA-SDFKLACYDPH 77 H I +AH+Y ++ + + QL+++P P P L+INP +D++++V DFK+ Y H Sbjct: 215 HKIVNAHIYEDQLELMRDVQLKREPFPLPKLEINPDIKTLEDLETWVTMDDFKVVGYQSH 274 Query: 76 QKIEMKMAV 50 + I+ +V Sbjct: 275 EPIKYPFSV 283
>TYSY_HAEI8 (Q4QM04) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 283 Score = 92.8 bits (229), Expect = 7e-19 Identities = 59/189 (31%), Positives = 94/189 (49%), Gaps = 5/189 (2%) Frame = -1 Query: 601 DLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTDLKK 422 D+G VYG Q R + G+ DQL ++N + DDR IL+ +NP + Sbjct: 103 DMGRVYGVQGRAWRKP--------NGETIDQLRKIVNNLTKGIDDRGEILTFFNPGEFDL 154 Query: 421 MALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPGEFV 242 L PC F + L YQRS D+ LG+ FN ++AQ+ G+ Sbjct: 155 GCLRPCMHTHTFSLVGDTLHLTSYQRSCDVPLGLNFNQIQVFTFLALMAQITGKKAGKAY 214 Query: 241 HVIGDAHVYSTHVQALEE-QLQKQPKPFPILKINP---LKKDIDSFVA-SDFKLACYDPH 77 H I +AH+Y ++ + + QL+++P P P L+INP +D++++V DFK+ Y H Sbjct: 215 HKIVNAHIYEDQLELMRDVQLKREPFPLPKLEINPDIKTLEDLETWVTMDDFKVVGYQSH 274 Query: 76 QKIEMKMAV 50 + I+ +V Sbjct: 275 EPIKYPFSV 283
>TYSY_PASMU (P57808) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 283 Score = 90.9 bits (224), Expect = 3e-18 Identities = 60/189 (31%), Positives = 93/189 (49%), Gaps = 5/189 (2%) Frame = -1 Query: 601 DLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTDLKK 422 D+G VYG Q R + G+ DQL ++N ++N DDR I++ +NP + + Sbjct: 103 DMGRVYGVQGRAWRKP--------NGETVDQLRKIVNNLRNGIDDRGEIMTFFNPGEFEL 154 Query: 421 MALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPGEFV 242 L PC F + L YQRS D+ LG+ FN ++AQ+ G+ Sbjct: 155 GCLRPCMHTHTFSLLGDTLYLTSYQRSCDVPLGLNFNQIQVFTFLALMAQITGKKAGKAY 214 Query: 241 HVIGDAHVYSTHVQALEE-QLQKQPKPFPILKINPLKK---DIDSFVA-SDFKLACYDPH 77 H I +AH+Y + ++ QL++ P P P L INP K D++++V DFK+ Y H Sbjct: 215 HKIINAHIYEDQLDLMKNVQLKRDPFPLPQLHINPEIKTLEDLETWVTMDDFKVTGYQCH 274 Query: 76 QKIEMKMAV 50 I+ +V Sbjct: 275 DAIKYPFSV 283
>TYSY_VIBCH (O66108) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 283 Score = 88.6 bits (218), Expect = 1e-17 Identities = 59/191 (30%), Positives = 92/191 (48%), Gaps = 5/191 (2%) Frame = -1 Query: 607 EGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTDL 428 E D+G VYG Q R + A G DQL +++ + DDR IL+ +NP + Sbjct: 101 EDDMGRVYGVQGRAW--------AKPDGGHIDQLKKIVDDLSRGVDDRGEILNFYNPGEF 152 Query: 427 KKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPGE 248 L PC F + L QRS D+ LG+ FN+ + ++AQ+ PG Sbjct: 153 HMGCLRPCMYSHHFSLLGDTLYLNSTQRSCDVPLGLNFNMVQVYVFLALMAQITGKKPGL 212 Query: 247 FVHVIGDAHVYSTHVQALEE-QLQKQPKPFPILKINPLKK---DIDSFVA-SDFKLACYD 83 H I +AH+Y ++ + + QL+++P P P INP K D++++V DF + Y Sbjct: 213 AYHKIVNAHIYQDQLELMRDVQLKREPFPAPQFHINPKIKTLQDLETWVTLDDFDVTGYQ 272 Query: 82 PHQKIEMKMAV 50 H I+ +V Sbjct: 273 FHDPIQYPFSV 283
>TYSY_STAEP (P0C0M4) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase) (Fragment)| Length = 97 Score = 88.2 bits (217), Expect = 2e-17 Identities = 47/98 (47%), Positives = 61/98 (62%) Frame = -1 Query: 343 SADMGLGVPFNIASYSLLTCMIAQVCDLSPGEFVHVIGDAHVYSTHVQALEEQLQKQPKP 164 SAD+ LGVPFNIASY+LLT ++A+ C L GEF+H GDAH+YS H+ A+ QL + Sbjct: 1 SADIFLGVPFNIASYALLTHLVAKECGLEVGEFIHTFGDAHIYSNHMDAIHTQLSRDSYL 60 Query: 163 FPILKINPLKKDIDSFVASDFKLACYDPHQKIEMKMAV 50 P LKIN K I D +L Y+ H I+ +AV Sbjct: 61 PPQLKIN-TDKSIFDINYEDLELINYESHPAIKAPIAV 97
>TYSY_MANSM (Q65VJ8) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 283 Score = 87.8 bits (216), Expect = 2e-17 Identities = 58/189 (30%), Positives = 92/189 (48%), Gaps = 5/189 (2%) Frame = -1 Query: 601 DLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTDLKK 422 D+G VYG Q R + G+ DQL ++N + DDR IL+ NP + Sbjct: 103 DMGRVYGVQGRAWRKP--------NGETVDQLRKIVNNLSRGIDDRGEILTFLNPGEFDL 154 Query: 421 MALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPGEFV 242 L PC F + L YQRS D+ LG+ FN ++AQ+ G+ Sbjct: 155 GCLRPCMYNHTFSLLGDTLYLTSYQRSCDVPLGLNFNQIQVFTFLALMAQITGKKAGQAY 214 Query: 241 HVIGDAHVYSTHVQALEE-QLQKQPKPFPILKINP---LKKDIDSFVA-SDFKLACYDPH 77 H I +AH+Y ++ + + QL+++P P P L+INP +D++++V DF + Y H Sbjct: 215 HKIVNAHIYEDQLELMRDVQLKREPFPSPKLEINPDIKTLEDLETWVTMDDFNVVGYQCH 274 Query: 76 QKIEMKMAV 50 + I+ +V Sbjct: 275 EPIKYPFSV 283
>TYSY_VIBPA (Q87SA0) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 283 Score = 87.4 bits (215), Expect = 3e-17 Identities = 58/191 (30%), Positives = 93/191 (48%), Gaps = 5/191 (2%) Frame = -1 Query: 607 EGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTDL 428 E D+G VYG Q R + A G DQL +++ + DDR IL+ +NP + Sbjct: 101 EDDMGRVYGVQGRAW--------AKPDGGHIDQLRKIVDDLTRGVDDRGEILNFYNPGEF 152 Query: 427 KKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPGE 248 L PC F + + L QRS D+ LG+ FN+ + ++AQ+ PG+ Sbjct: 153 HMGCLRPCMYSHHFSLLDDTLYLNSTQRSCDVPLGLNFNMVQVYVFLAIMAQITGKKPGQ 212 Query: 247 FVHVIGDAHVYSTHVQALEE-QLQKQPKPFPILKINPLKK---DIDSFVA-SDFKLACYD 83 H I +AH+Y ++ + + QL+++P P INP K D++++V DF + Y+ Sbjct: 213 AFHKIVNAHIYEDQLELMRDVQLKREPLQAPTFHINPEIKSLEDLETWVTLDDFWVEGYE 272 Query: 82 PHQKIEMKMAV 50 H I +V Sbjct: 273 HHDPIRYPFSV 283
>TYSY_PHOPR (Q6LUM1) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 283 Score = 87.4 bits (215), Expect = 3e-17 Identities = 61/191 (31%), Positives = 90/191 (47%), Gaps = 5/191 (2%) Frame = -1 Query: 607 EGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTDL 428 E D+G VYG Q R + G DQL +++ + DDR IL+ +NP + Sbjct: 101 EDDMGRVYGVQGRSWQKP--------DGSTIDQLRKIVDNLSEGIDDRGEILTFYNPGEF 152 Query: 427 KKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPGE 248 L PC F + L YQRS D+ LG+ FN L ++AQ+ PG Sbjct: 153 DLGCLRPCMHTHTFSLLGDTLHLTSYQRSCDVPLGLNFNQVQVYTLLALVAQITGKKPGL 212 Query: 247 FVHVIGDAHVYSTHVQALEE-QLQKQPKPFPILKINPLKK---DIDSFVA-SDFKLACYD 83 H I +AH+Y + L + QL + P P L INP K D++++V DF + Y+ Sbjct: 213 AYHKIINAHIYEDQLSLLRDVQLTRTPFAAPKLIINPKIKCLEDLETWVTMDDFDVIGYE 272 Query: 82 PHQKIEMKMAV 50 H+ I+ +V Sbjct: 273 HHEAIKYPFSV 283
>TYSY_VIBVU (Q8DER9) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 283 Score = 86.7 bits (213), Expect = 5e-17 Identities = 58/191 (30%), Positives = 92/191 (48%), Gaps = 5/191 (2%) Frame = -1 Query: 607 EGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTDL 428 E D+G VYG Q R + A G DQL +++ + DDR IL+ +NP + Sbjct: 101 EDDMGRVYGVQGRAW--------AKPDGGHIDQLRKIVDDLTRGVDDRGEILNFYNPGEF 152 Query: 427 KKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPGE 248 L PC F + L QRS D+ LG+ FN+ + ++AQ+ PG+ Sbjct: 153 HMGCLRPCMYSHHFSLLGDTLYLNSTQRSCDVPLGLNFNMVQVYVFLAIMAQITGKKPGQ 212 Query: 247 FVHVIGDAHVYSTHVQALEE-QLQKQPKPFPILKINPLKK---DIDSFVA-SDFKLACYD 83 H I +AH+Y + + + QL+++P P INP K D++++V DF + Y+ Sbjct: 213 AFHKIVNAHIYEDQLALMRDVQLKREPLQAPTFHINPEIKSLEDLETWVTLDDFWVEGYE 272 Query: 82 PHQKIEMKMAV 50 H I+ +V Sbjct: 273 HHDPIQYPFSV 283
>TYSY_VIBVY (Q7MNN6) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 283 Score = 85.5 bits (210), Expect = 1e-16 Identities = 57/191 (29%), Positives = 92/191 (48%), Gaps = 5/191 (2%) Frame = -1 Query: 607 EGDLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTDL 428 + D+G VYG Q R + A G DQL +++ + DDR IL+ +NP + Sbjct: 101 DDDMGRVYGVQGRAW--------AKPDGGHIDQLRKIVDDLTRGVDDRGEILNFYNPGEF 152 Query: 427 KKMALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPGE 248 L PC F + L QRS D+ LG+ FN+ + ++AQ+ PG+ Sbjct: 153 HMGCLRPCMYSHHFSLLGDTLYLNSTQRSCDVPLGLNFNMVQVYVFLAIMAQITGKKPGQ 212 Query: 247 FVHVIGDAHVYSTHVQALEE-QLQKQPKPFPILKINPLKK---DIDSFVA-SDFKLACYD 83 H I +AH+Y + + + QL+++P P INP K D++++V DF + Y+ Sbjct: 213 AFHKIVNAHIYEDQLALMRDVQLKREPLQAPTFHINPEIKSLEDLETWVTLDDFWVEGYE 272 Query: 82 PHQKIEMKMAV 50 H I+ +V Sbjct: 273 HHDPIQYPFSV 283
>TYSY_HAEDU (Q7VMH2) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 283 Score = 75.1 bits (183), Expect = 2e-13 Identities = 53/189 (28%), Positives = 88/189 (46%), Gaps = 5/189 (2%) Frame = -1 Query: 601 DLGPVYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTDLKK 422 D+G VYG R F AD+ D L +++ + N D+R I + ++P Sbjct: 103 DMGLVYGAIGRKFPK------ADHGS--LDLLKQIVDDLSNGIDNRGEIYTFYHPGAFHM 154 Query: 421 MALPPCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPGEFV 242 L PC F + +G L QRSAD+ LG+ +N+ ++AQ+ + G+ Sbjct: 155 GCLRPCLYSHHFSLLDGTLYLNSTQRSADVPLGLNWNMVQCYTFLALMAQITNHKAGQVF 214 Query: 241 HVIGDAHVYSTHVQALEE-QLQKQPKPFPILKINPLKKDIDSF----VASDFKLACYDPH 77 H I +AH+Y + + + QL+++P P L INP K ++ DFK+ Y H Sbjct: 215 HKIVNAHIYEDQLALMRDVQLKREPFATPTLTINPAIKSLEDLEIWVTLDDFKVENYFYH 274 Query: 76 QKIEMKMAV 50 I+ ++ Sbjct: 275 PSIQYPFSI 283
>TYSY_STRT1 (Q5M0S7) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 286 Score = 62.0 bits (149), Expect = 1e-09 Identities = 48/152 (31%), Positives = 73/152 (48%), Gaps = 11/152 (7%) Frame = -1 Query: 502 DVINKI----KNNPDDRRIILSAWNPTDLKKMA-LPPCHMFAQFYV----ENGELSCQMY 350 D+IN++ + NP +RR ++S W+ ++ A L PC F V E+ L + Sbjct: 124 DIINRLLAQLEANPWNRRNVISLWDYEAFEETAGLQPCAFQTMFDVRRVGEDVYLDATLT 183 Query: 349 QRSADMGLGVPFNIASYSLLTCMIAQVCDLSPGEFVHVIGDAHVYSTHVQALEEQLQKQP 170 QRS DM + N Y L MIA+ G+F + I + H+Y + EE L++QP Sbjct: 184 QRSNDMLVAHHINAMQYVALQMMIAKHFGWKIGKFFYFINNLHIYDNQFEQAEELLKRQP 243 Query: 169 KPF-PILKIN-PLKKDIDSFVASDFKLACYDP 80 P L +N P + + DF+L YDP Sbjct: 244 SDCQPRLVLNVPDETNFFDIKPEDFELVDYDP 275
>TYSY_STRMU (Q8DUI4) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 279 Score = 62.0 bits (149), Expect = 1e-09 Identities = 45/156 (28%), Positives = 74/156 (47%), Gaps = 8/156 (5%) Frame = -1 Query: 523 KGFDQLADVINKIKNNPDDRRIILSAWNPTDLKKM-ALPPCHMFAQFYVEN--GE--LSC 359 K D + ++ +++ NP +RR ++S W+ +K L PC F V GE L Sbjct: 114 KKHDIMNKILKQLEENPWNRRNVISLWDYEAFEKTEGLLPCAFQIMFDVRRVKGEIYLDA 173 Query: 358 QMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPGEFVHVIGDAHVYSTHVQALEEQLQ 179 + QRS DM + N Y L MIA+ G+F + + + H+Y + EE L+ Sbjct: 174 TLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFVNNLHIYDNQFEQAEELLR 233 Query: 178 KQP---KPFPILKINPLKKDIDSFVASDFKLACYDP 80 ++P +P +L + P K + DF+L Y+P Sbjct: 234 REPVVCQPHLVLNV-PNKTNFFDIKPEDFELLDYEP 268
>TYSY_STRA5 (Q8DZ07) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 279 Score = 61.6 bits (148), Expect = 2e-09 Identities = 46/150 (30%), Positives = 72/150 (48%), Gaps = 7/150 (4%) Frame = -1 Query: 508 LADVINKIKNNPDDRRIILSAWNPTDLKKM-ALPPCHMFAQFYVE--NGEL--SCQMYQR 344 ++ ++ ++++NP +RR ++S W+ ++ L PC F V NGEL + QR Sbjct: 119 ISKLLKQLEDNPWNRRNVISLWDYEAFEETEGLLPCAFQTMFDVRRVNGELYLDATLTQR 178 Query: 343 SADMGLGVPFNIASYSLLTCMIAQVCDLSPGEFVHVIGDAHVYSTHVQALEEQLQKQPKP 164 S DM + N Y L MIA+ G+F + I + H+Y + +E L++QP Sbjct: 179 SNDMLVAHHINAMQYVALQMMIAKHFGWRVGKFFYFINNLHIYDNQFEQAQELLKRQPSE 238 Query: 163 F-PILKIN-PLKKDIDSFVASDFKLACYDP 80 P L +N P D DF L YDP Sbjct: 239 CNPKLVLNVPDGTDFFDIKPDDFALVDYDP 268
>TYSY_STRA3 (Q8E4L6) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 279 Score = 61.6 bits (148), Expect = 2e-09 Identities = 46/150 (30%), Positives = 72/150 (48%), Gaps = 7/150 (4%) Frame = -1 Query: 508 LADVINKIKNNPDDRRIILSAWNPTDLKKM-ALPPCHMFAQFYVE--NGEL--SCQMYQR 344 ++ ++ ++++NP +RR ++S W+ ++ L PC F V NGEL + QR Sbjct: 119 ISKLLKQLEDNPWNRRNVISLWDYEAFEETEGLLPCAFQTMFDVRRVNGELYLDATLTQR 178 Query: 343 SADMGLGVPFNIASYSLLTCMIAQVCDLSPGEFVHVIGDAHVYSTHVQALEEQLQKQPKP 164 S DM + N Y L MIA+ G+F + I + H+Y + +E L++QP Sbjct: 179 SNDMLVAHHINAMQYVALQMMIAKHFGWRVGKFFYFINNLHIYDNQFEQAQELLKRQPSE 238 Query: 163 F-PILKIN-PLKKDIDSFVASDFKLACYDP 80 P L +N P D DF L YDP Sbjct: 239 CNPKLVLNVPDGTDFFDIKPDDFALVDYDP 268
>TYSY_STRT2 (Q5M5B3) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 286 Score = 61.2 bits (147), Expect = 2e-09 Identities = 48/152 (31%), Positives = 73/152 (48%), Gaps = 11/152 (7%) Frame = -1 Query: 502 DVINKI----KNNPDDRRIILSAWNPTDLKKMA-LPPCHMFAQFYV----ENGELSCQMY 350 D+IN++ + NP +RR ++S W+ ++ A L PC F V E+ L + Sbjct: 124 DIINRLLAQLEANPWNRRNVISLWDYEAFEETAGLQPCAFQTMFDVRRVGEDVYLDGTLT 183 Query: 349 QRSADMGLGVPFNIASYSLLTCMIAQVCDLSPGEFVHVIGDAHVYSTHVQALEEQLQKQP 170 QRS DM + N Y L MIA+ G+F + I + H+Y + EE L++QP Sbjct: 184 QRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNLHIYDNQFEQAEELLKRQP 243 Query: 169 KPF-PILKIN-PLKKDIDSFVASDFKLACYDP 80 P L +N P + + DF+L YDP Sbjct: 244 SDCQPRLVLNVPDETNFFDIKPEDFELVDYDP 275
>TYSY_STRR6 (P67050) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 279 Score = 60.5 bits (145), Expect = 4e-09 Identities = 48/153 (31%), Positives = 74/153 (48%), Gaps = 12/153 (7%) Frame = -1 Query: 502 DVINKI----KNNPDDRRIILSAWNPTDLKKM-ALPPCHMFAQFYVE--NGE--LSCQMY 350 D+INK+ + NP +RR I+S W+ ++ L PC F V +GE L + Sbjct: 117 DIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMFDVRRVDGEIYLDATLT 176 Query: 349 QRSADMGLGVPFNIASYSLLTCMIAQVCDLSPGEFVHVIGDAHVYSTHVQALEEQLQKQP 170 QRS DM + N Y L MIA+ G+F + I + H+Y + +E L+++P Sbjct: 177 QRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNLHIYDNQFEQAQELLRREP 236 Query: 169 ---KPFPILKINPLKKDIDSFVASDFKLACYDP 80 +P +L + P + A DF+L YDP Sbjct: 237 SNCQPRLVLNV-PDGTNFFDIKAEDFELVDYDP 268
>TYSY_STRPN (P67049) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 279 Score = 60.5 bits (145), Expect = 4e-09 Identities = 48/153 (31%), Positives = 74/153 (48%), Gaps = 12/153 (7%) Frame = -1 Query: 502 DVINKI----KNNPDDRRIILSAWNPTDLKKM-ALPPCHMFAQFYVE--NGE--LSCQMY 350 D+INK+ + NP +RR I+S W+ ++ L PC F V +GE L + Sbjct: 117 DIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMFDVRRVDGEIYLDATLT 176 Query: 349 QRSADMGLGVPFNIASYSLLTCMIAQVCDLSPGEFVHVIGDAHVYSTHVQALEEQLQKQP 170 QRS DM + N Y L MIA+ G+F + I + H+Y + +E L+++P Sbjct: 177 QRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNLHIYDNQFEQAQELLRREP 236 Query: 169 ---KPFPILKINPLKKDIDSFVASDFKLACYDP 80 +P +L + P + A DF+L YDP Sbjct: 237 SNCQPRLVLNV-PDGTNFFDIKAEDFELVDYDP 268
>TYSY_STRP3 (P67052) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 279 Score = 57.8 bits (138), Expect = 2e-08 Identities = 43/156 (27%), Positives = 73/156 (46%), Gaps = 8/156 (5%) Frame = -1 Query: 523 KGFDQLADVINKIKNNPDDRRIILSAWNPTDLKKM-ALPPCHMFAQFYVEN-GE---LSC 359 K D ++ ++ ++ NP +RR ++S W+ ++ L PC F V GE L Sbjct: 114 KKHDIISKILKQLAENPWNRRNVISLWDYEAFEETKGLLPCAFQIMFDVRRVGEDLYLDA 173 Query: 358 QMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPGEFVHVIGDAHVYSTHVQALEEQLQ 179 + QRS D+ + N Y L MIA+ G+F + + + H+Y +E L+ Sbjct: 174 SLTQRSNDILVAHHINAMQYVALQMMIAKHFGWKIGKFFYFVNNLHIYDNQFDQAQELLK 233 Query: 178 KQP---KPFPILKINPLKKDIDSFVASDFKLACYDP 80 +QP +P +L + P + + DF+L YDP Sbjct: 234 RQPVASQPKLVLNV-PDRTNFFDIKPDDFELQNYDP 268
>TYSY_STRP1 (P67051) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 279 Score = 57.8 bits (138), Expect = 2e-08 Identities = 43/156 (27%), Positives = 73/156 (46%), Gaps = 8/156 (5%) Frame = -1 Query: 523 KGFDQLADVINKIKNNPDDRRIILSAWNPTDLKKM-ALPPCHMFAQFYVEN-GE---LSC 359 K D ++ ++ ++ NP +RR ++S W+ ++ L PC F V GE L Sbjct: 114 KKHDIISKILKQLAENPWNRRNVISLWDYEAFEETKGLLPCAFQIMFDVRRVGEDLYLDA 173 Query: 358 QMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPGEFVHVIGDAHVYSTHVQALEEQLQ 179 + QRS D+ + N Y L MIA+ G+F + + + H+Y +E L+ Sbjct: 174 SLTQRSNDILVAHHINAMQYVALQMMIAKHFGWKIGKFFYFVNNLHIYDNQFDQAQELLK 233 Query: 178 KQP---KPFPILKINPLKKDIDSFVASDFKLACYDP 80 +QP +P +L + P + + DF+L YDP Sbjct: 234 RQPVASQPKLVLNV-PDRTNFFDIKPDDFELQNYDP 268
>TYSY_STRP8 (Q8P1D1) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 279 Score = 56.2 bits (134), Expect = 7e-08 Identities = 43/156 (27%), Positives = 72/156 (46%), Gaps = 8/156 (5%) Frame = -1 Query: 523 KGFDQLADVINKIKNNPDDRRIILSAWNPTDLKKM-ALPPCHMFAQFYVEN-GE---LSC 359 K D ++ ++ ++ NP +RR ++S W+ ++ L PC F V GE L Sbjct: 114 KKHDIISKILKQLAENPWNRRNVISLWDYEAFEETKGLLPCAFQIMFDVRRVGEDLYLDA 173 Query: 358 QMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPGEFVHVIGDAHVYSTHVQALEEQLQ 179 + QRS D+ + N Y L MIA+ G+F + + + H+Y +E L+ Sbjct: 174 SLTQRSNDILVAHHINAMQYVALQMMIAKHFGWKIGKFFYFVNNLHIYDNQFDQAQELLK 233 Query: 178 KQP---KPFPILKINPLKKDIDSFVASDFKLACYDP 80 +QP +P +L + P + DF+L YDP Sbjct: 234 RQPVASQPKLVLNV-PDGTNFFDIKPDDFELQNYDP 268
>TYSY_STRP6 (Q5XCM3) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 279 Score = 56.2 bits (134), Expect = 7e-08 Identities = 43/156 (27%), Positives = 72/156 (46%), Gaps = 8/156 (5%) Frame = -1 Query: 523 KGFDQLADVINKIKNNPDDRRIILSAWNPTDLKKM-ALPPCHMFAQFYVEN-GE---LSC 359 K D ++ ++ ++ NP +RR ++S W+ ++ L PC F V GE L Sbjct: 114 KKHDIISKILKQLAENPWNRRNVISLWDYEAFEETKGLLPCAFQIMFDVRRVGEDLYLDA 173 Query: 358 QMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPGEFVHVIGDAHVYSTHVQALEEQLQ 179 + QRS D+ + N Y L MIA+ G+F + + + H+Y +E L+ Sbjct: 174 SLTQRSNDILVAHHINAMQYVALQMMIAKHFGWKIGKFFYFVNNLHIYDNQFDQAQELLK 233 Query: 178 KQP---KPFPILKINPLKKDIDSFVASDFKLACYDP 80 +QP +P +L + P + DF+L YDP Sbjct: 234 RQPVASQPKLVLNV-PDGTNFFDIKPDDFELQNYDP 268
>DUHM_BPSP1 (P31654) Deoxyuridylate hydroxymethyltransferase (EC 2.1.2.-)| (Deoxyuridylate hydroxymethylase) (dUMP hydroxymethylase) (dUMP-HMase) Length = 383 Score = 54.7 bits (130), Expect = 2e-07 Identities = 37/121 (30%), Positives = 56/121 (46%), Gaps = 8/121 (6%) Frame = -1 Query: 514 DQLADVINKIKNNPDDRRIILSAWNP------TDLKKMALPPCHMFAQFYVENGELSCQM 353 DQL DV KIK +PD R+ + +NP D K PC++ F + NG+L + Sbjct: 123 DQLRDVYEKIKADPDTRQAVAVIYNPLFDNINNDTKDR---PCNLLLSFKLRNGKLDLSV 179 Query: 352 YQRSADMGLGV-PFNIASYSLLTCMIAQVCDLSPGEFVHVIGDAHVYSTHVQA-LEEQLQ 179 Y RS D+ G N+ +S + +A + G + + HVY A + E +Q Sbjct: 180 YNRSNDLHWGTFGANLCQFSTILEAMATWLGVEVGSYYQITDSLHVYLDDYGAKITEDIQ 239 Query: 178 K 176 K Sbjct: 240 K 240
>TYSY_LACLA (P19368) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 279 Score = 51.6 bits (122), Expect = 2e-06 Identities = 39/159 (24%), Positives = 70/159 (44%), Gaps = 9/159 (5%) Frame = -1 Query: 529 TGKGFDQLADVINKIKNNPDDRRIILSAWNPTDLKKM-ALPPCHMFAQFYVENGE----- 368 T K ++ + +++ + NP +RR I++ W D ++ L PC F V + Sbjct: 111 TVKKYNIIGKLLDGLAKNPWNRRNIINLWQYEDFEETEGLLPCAFQTMFDVRREQDGQIY 170 Query: 367 LSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPGEFVHVIGDAHVYSTHVQALEE 188 L + QRS DM + N Y L MIA+ G+F + + + H+Y + E Sbjct: 171 LDATLIQRSNDMLVAHHINAMQYVALQMMIAKHFSWKVGKFFYFVNNLHIYDNQFEQANE 230 Query: 187 QLQK---QPKPFPILKINPLKKDIDSFVASDFKLACYDP 80 +++ +P +L + P + DF+L Y+P Sbjct: 231 LVKRTASDKEPRLVLNV-PDGTNFFDIKPEDFELVDYEP 268
>TYSY_METMA (Q8PXI1) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 217 Score = 50.8 bits (120), Expect = 3e-06 Identities = 35/125 (28%), Positives = 53/125 (42%) Frame = -1 Query: 589 VYGFQWRHFGAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNPTDLKKMALP 410 + G + F Y ++ G+ DQ+ VI K+K +P RR W P K+ Sbjct: 79 ISGENIQDFEYTYGQRLRNWNGE-VDQIEYVIEKLKESPTSRRATAVTWIPPVDTKVNEV 137 Query: 409 PCHMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPGEFVHVIG 230 PC + F + + ++ RS D G P N+ S L +A+ + PG V Sbjct: 138 PCMILDDFKIRDEKVHLTTLFRSHDFGGAYPANLYGLSKLLEYVAEKVGVEPGVITTVSI 197 Query: 229 DAHVY 215 AHVY Sbjct: 198 SAHVY 202
>TYSY_METAC (Q8THH4) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 217 Score = 50.1 bits (118), Expect = 5e-06 Identities = 31/100 (31%), Positives = 44/100 (44%) Frame = -1 Query: 514 DQLADVINKIKNNPDDRRIILSAWNPTDLKKMALPPCHMFAQFYVENGELSCQMYQRSAD 335 DQ+ VI K++ +P RR W P K+ PC + F + +G++ RS D Sbjct: 103 DQIEYVIEKLQESPTSRRATAVTWIPPVDTKVNEVPCMILDDFKIRDGKVHLTTLFRSHD 162 Query: 334 MGLGVPFNIASYSLLTCMIAQVCDLSPGEFVHVIGDAHVY 215 G P N+ S L +A + PG V AHVY Sbjct: 163 FGGAYPANLYGLSKLLEYVAGRVGVEPGMITTVSISAHVY 202
>TYSY_METTH (O26868) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 221 Score = 45.4 bits (106), Expect = 1e-04 Identities = 32/116 (27%), Positives = 52/116 (44%), Gaps = 2/116 (1%) Frame = -1 Query: 520 GFDQLADVINKIKNNPDDRRIILSAWNPTDLKKMALPPCHMFAQFYVENGELSCQMYQRS 341 G DQL + I ++KN + RR + W+P + PC + F + +G L RS Sbjct: 107 GVDQLDEAIRRLKNCTESRRATMVTWDPPEDTASDEVPCMILVDFKIRDGRLFTTALWRS 166 Query: 340 ADM-GLGVPFNIASYSLLTCMIAQVCDLSPGEF-VHVIGDAHVYSTHVQALEEQLQ 179 D+ G P N + L +A + G +H I AH+Y + + EE ++ Sbjct: 167 HDIYGAWFP-NAVGLAYLADHVAAEVGVEVGHITIHSI-SAHIYEVNFKEAEEVIK 220
>TYSY_METKA (Q8TVL9) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 209 Score = 43.1 bits (100), Expect = 6e-04 Identities = 32/118 (27%), Positives = 52/118 (44%), Gaps = 2/118 (1%) Frame = -1 Query: 562 GAEYSDMHADYTGKGFDQLADVINKIKNNPDDRRIILSAWNP-TDLKKMALPPCHMFAQF 386 G EY+ H G DQ+ ++ ++ + + RR I W+P DL + + PC Q Sbjct: 85 GFEYTYGHRLRRYFGLDQVTKIVERLSESNNTRRAIAVTWDPRRDLDEEEV-PCLTALQL 143 Query: 385 YVENGE-LSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPGEFVHVIGDAHVY 215 + G L + RS D+G + N+ + L +A+ L P +AHVY Sbjct: 144 QSDGGSGLELHAFYRSWDVGKALVANMIALRRLQEHVAERAGLEPTTLTVYAANAHVY 201
>TYSY_METJA (Q57931) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 222 Score = 42.4 bits (98), Expect = 0.001 Identities = 29/111 (26%), Positives = 46/111 (41%), Gaps = 5/111 (4%) Frame = -1 Query: 532 YTGKGFDQLADVINKIKNNPDDRRIILSAWNPT-DLK----KMALPPCHMFAQFYVENGE 368 Y + +Q+ +I K+ + RR + WNP D++ + PC QF + NG+ Sbjct: 92 YADEKINQIDYIIEKLNQQKNSRRAVAITWNPKIDIEVSRDERGSVPCLQLVQFLIRNGK 151 Query: 367 LSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPGEFVHVIGDAHVY 215 L + RS D L N L IA+ + G + H H+Y Sbjct: 152 LYQTVIFRSNDALLAFVSNAIGLITLGEYIAKKVGVGYGTYTHHAISMHIY 202
>TYSY_METTM (P80305) Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)| Length = 222 Score = 40.4 bits (93), Expect = 0.004 Identities = 31/116 (26%), Positives = 50/116 (43%), Gaps = 2/116 (1%) Frame = -1 Query: 520 GFDQLADVINKIKNNPDDRRIILSAWNPTDLKKMALPPCHMFAQFYVENGELSCQMYQRS 341 G DQ+ I ++KN + RR + W+P + PC + F V G L RS Sbjct: 107 GVDQVDRAIERLKNCKESRRATMVTWDPKIDTESDEVPCMILVDFKVREGRLFTTALWRS 166 Query: 340 ADM-GLGVPFNIASYSLLTCMIAQVCDLSPGEF-VHVIGDAHVYSTHVQALEEQLQ 179 D+ G P N + L +A + G +H I AH+Y + + +E ++ Sbjct: 167 HDIYGAWFP-NAVGLAYLADHVASEVGVEVGHITIHSI-SAHIYEVNFKEAKEVIK 220
>MOTB_SALTY (P55892) Chemotaxis protein motB (Motility protein B)| Length = 309 Score = 30.8 bits (68), Expect = 3.3 Identities = 16/48 (33%), Positives = 26/48 (54%), Gaps = 6/48 (12%) Frame = -1 Query: 187 QLQKQP------KPFPILKINPLKKDIDSFVASDFKLACYDPHQKIEM 62 +++KQP K ++N L+ D+D + SD KL PH KI++ Sbjct: 97 EVEKQPNIDELKKRMEQSRLNKLRGDLDQLIESDPKLRALRPHLKIDL 144
>SYV_XYLFA (Q9PH12) Valyl-tRNA synthetase (EC 6.1.1.9) (Valine--tRNA ligase)| (ValRS) Length = 994 Score = 30.4 bits (67), Expect = 4.2 Identities = 21/56 (37%), Positives = 32/56 (57%), Gaps = 4/56 (7%) Frame = -2 Query: 522 KVLIS*LMSLTRSRITLTIG----VSFCLHGIQQISRRWHFHLATCLHSFMSRMEN 367 K+++S +L R R TL + VS L G Q++ RR H AT LH F+ ++E+ Sbjct: 847 KIMVS---ALRRIRSTLNVPPSRRVSLLLQGDQEVDRRRITHFATALH-FLLKLEH 898
>SYE_BUCAI (P57173) Glutamyl-tRNA synthetase (EC 6.1.1.17) (Glutamate--tRNA| ligase) (GluRS) Length = 467 Score = 30.4 bits (67), Expect = 4.2 Identities = 17/56 (30%), Positives = 29/56 (51%) Frame = +2 Query: 395 KHVARWKCHLLEICWIPCRQNDTPIVRVILDLVNDIS*LIKTFPRVVSMHVRIFST 562 K+ R C +L+ C+ + + I ++ND+S LIK + +SM +RI T Sbjct: 378 KYFTRKNCFILQTCYKKIEKLSIWDNKNISKIINDVSELIKVTKKEISMILRISMT 433
>FDHD_ERWCT (Q6DB09) Protein fdhD homolog| Length = 277 Score = 30.4 bits (67), Expect = 4.2 Identities = 21/59 (35%), Positives = 33/59 (55%) Frame = -1 Query: 364 SCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDLSPGEFVHVIGDAHVYSTHVQALEE 188 S +M Q+SA G+ + F +++ + L +AQ C+L+ F G A +Y TH Q L E Sbjct: 221 SYEMVQKSAMCGVEILFAVSAATSLAVDVAQRCNLTLVGFCRP-GQATIY-THPQRLSE 277
>INV1_HANAN (P40912) Invertase precursor (EC 3.2.1.26) (Beta-fructofuranosidase| 2) (Saccharase) Length = 550 Score = 30.0 bits (66), Expect = 5.6 Identities = 22/69 (31%), Positives = 33/69 (47%) Frame = -1 Query: 307 ASYSLLTCMIAQVCDLSPGEFVHVIGDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKD 128 +S SL+ + D++P + + VY T L E L K + ++N LK D Sbjct: 326 SSMSLVRNYTLKYVDVNPENYGLTLIQKPVYDTKETRLNETL-KTLETINEYEVNDLKLD 384 Query: 127 IDSFVASDF 101 SFVA+DF Sbjct: 385 KSSFVATDF 393
>IATR_SHEEP (P62757) Inter-alpha-trypsin inhibitor (ITI) (Inhibitory fragment| of ITI) (Fragment) Length = 123 Score = 30.0 bits (66), Expect = 5.6 Identities = 15/51 (29%), Positives = 23/51 (45%), Gaps = 1/51 (1%) Frame = -1 Query: 409 PC-HMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDL 260 PC MF +++ ++C+ + MG G F L TC Q C+L Sbjct: 13 PCLGMFKRYFYNGTSMACETFYYGGCMGNGNNFPSEKECLQTCRTVQACNL 63
>IATR_CAPHI (P62756) Inter-alpha-trypsin inhibitor (ITI) (GIK-14) (Inhibitory| fragment of ITI) (Fragment) Length = 123 Score = 30.0 bits (66), Expect = 5.6 Identities = 15/51 (29%), Positives = 23/51 (45%), Gaps = 1/51 (1%) Frame = -1 Query: 409 PC-HMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDL 260 PC MF +++ ++C+ + MG G F L TC Q C+L Sbjct: 13 PCLGMFKRYFYNGTSMACETFYYGGCMGNGNNFPSEKECLQTCRTVQACNL 63
>AMBP_MESAU (Q60559) AMBP protein precursor [Contains: Alpha-1-microglobulin;| Inter-alpha-trypsin inhibitor light chain (ITI-LC) (Bikunin) (HI-30); Trypstatin] Length = 349 Score = 29.6 bits (65), Expect = 7.2 Identities = 14/51 (27%), Positives = 21/51 (41%), Gaps = 1/51 (1%) Frame = -1 Query: 409 PC-HMFAQFYVENGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAQVCDL 260 PC M ++Y ++C+ + +G G FN L TC C L Sbjct: 238 PCLGMIEKYYYNGASMACETFHYGGCLGNGNNFNSEKECLQTCRTVAACSL 288
>MOTB_ECOLI (P0AF06) Chemotaxis protein motB (Motility protein B)| Length = 308 Score = 29.3 bits (64), Expect = 9.5 Identities = 15/57 (26%), Positives = 27/57 (47%) Frame = -1 Query: 232 GDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQKIEM 62 GD + S + +++ K ++ L+ D+D + SD KL PH KI++ Sbjct: 87 GDDYTQSQGEVNKQPNIEELKKRMEQSRLRKLRGDLDQLIESDPKLRALRPHLKIDL 143
>MOTB_ECO57 (P0AF07) Chemotaxis protein motB (Motility protein B)| Length = 308 Score = 29.3 bits (64), Expect = 9.5 Identities = 15/57 (26%), Positives = 27/57 (47%) Frame = -1 Query: 232 GDAHVYSTHVQALEEQLQKQPKPFPILKINPLKKDIDSFVASDFKLACYDPHQKIEM 62 GD + S + +++ K ++ L+ D+D + SD KL PH KI++ Sbjct: 87 GDDYTQSQGEVNKQPNIEELKKRMEQSRLRKLRGDLDQLIESDPKLRALRPHLKIDL 143 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 87,181,563 Number of Sequences: 219361 Number of extensions: 1756506 Number of successful extensions: 5453 Number of sequences better than 10.0: 194 Number of HSP's better than 10.0 without gapping: 5122 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5290 length of database: 80,573,946 effective HSP length: 107 effective length of database: 57,102,319 effective search space used: 5481822624 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
