ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
menu 
| Clone Name | rbags17c03 |
|---|---|
| Clone Library Name | barley_pub |
>IRAK4_HUMAN (Q9NWZ3) Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1)| (IRAK-4) (NY-REN-64 antigen) Length = 460 Score = 63.9 bits (154), Expect = 3e-10 Identities = 39/119 (32%), Positives = 67/119 (56%), Gaps = 2/119 (1%) Frame = -1 Query: 551 TRSVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVK 372 T +VG+ YMAPE L GEI+ +SDIYS G++++EI T + + + + +D + Sbjct: 345 TSRIVGTTAYMAPEAL-RGEITPKSDIYSFGVVLLEIITGL--PAVDEHREPQLLLDIKE 401 Query: 371 ENWTLEKIMSEYIELEEHAFD--QVEACINIGLQCVEIDQKKRPSIETIVNMLNKLPVS 201 E EK + +YI+ + + D VEA ++ QC+ + KRP I+ + +L ++ S Sbjct: 402 EIEDEEKTIEDYIDKKMNDADSTSVEAMYSVASQCLHEKKNKRPDIKKVQQLLQEMTAS 460
>NAK_ARATH (P43293) Probable serine/threonine-protein kinase NAK (EC 2.7.11.1)| Length = 389 Score = 63.5 bits (153), Expect = 4e-10 Identities = 36/125 (28%), Positives = 68/125 (54%), Gaps = 7/125 (5%) Frame = -1 Query: 542 VVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEI--STRXMNSSSTDQKH-----ARKYI 384 V+G+ GY APEYL G +S +SD+YS G++++E+ R ++ + +H AR Y+ Sbjct: 240 VMGTQGYAAPEYLATGHLSVKSDVYSFGVVLLELLSGRRAIDKNQPVGEHNLVDWARPYL 299 Query: 383 DGVKENWTLEKIMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNKLPV 204 + L ++M ++ +++ + + L C+ ID K RP++ IV + +L + Sbjct: 300 TNKRR---LLRVMDPRLQ-GQYSLTRALKIAVLALDCISIDAKSRPTMNEIVKTMEELHI 355 Query: 203 SEEVS 189 +E S Sbjct: 356 QKEAS 360
>RLK5_ARATH (P47735) Receptor-like protein kinase 5 precursor (EC 2.7.11.1)| Length = 999 Score = 63.2 bits (152), Expect = 5e-10 Identities = 34/112 (30%), Positives = 62/112 (55%), Gaps = 1/112 (0%) Frame = -1 Query: 542 VVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEIST-RXMNSSSTDQKHARKYIDGVKEN 366 + GS GY+APEY+Y ++ +SDIYS G++++E+ T + S K K++ + Sbjct: 858 IAGSCGYIAPEYVYTLRVNEKSDIYSFGVVLLELVTGKQPTDSELGDKDMAKWVCTALDK 917 Query: 365 WTLEKIMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNKL 210 LE ++ ++L+ +++ I+IGL C RPS+ +V ML ++ Sbjct: 918 CGLEPVIDPKLDLKFK--EEISKVIHIGLLCTSPLPLNRPSMRKVVIMLQEV 967
>SRK6_BRAOE (Q09092) Putative serine/threonine-protein kinase receptor precursor| (EC 2.7.11.1) (S-receptor kinase) (SRK) Length = 849 Score = 59.7 bits (143), Expect = 5e-09 Identities = 35/119 (29%), Positives = 61/119 (51%), Gaps = 9/119 (7%) Frame = -1 Query: 551 TRSVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVK 372 T VVG+ GYM+PEY G S +SD++S G+I++EI + N + + + V Sbjct: 687 TMKVVGTYGYMSPEYAMYGIFSEKSDVFSFGVIVLEIVSGKKNRGFYNLDYENDLLSYVW 746 Query: 371 ENW-------TLEKIMSEYIELEEHAF--DQVEACINIGLQCVEIDQKKRPSIETIVNM 222 W ++ ++ + + + F +V CI IGL CV+ + RP++ ++V M Sbjct: 747 SRWKEGRALEIVDPVIVDSLSSQPSIFQPQEVLKCIQIGLLCVQELAEHRPAMSSVVWM 805
>SIRK_ARATH (O64483) Senescence-induced receptor-like serine/threonine-protein| kinase precursor (FLG22-induced receptor-like kinase 1) Length = 876 Score = 59.3 bits (142), Expect = 7e-09 Identities = 31/113 (27%), Positives = 60/113 (53%), Gaps = 2/113 (1%) Frame = -1 Query: 542 VVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEIST--RXMNSSSTDQKHARKYIDGVKE 369 V GS+GY+ PEY +++ +SD+YSLG++++E+ T + SS T++ H ++ + Sbjct: 734 VAGSIGYLDPEYYSTRQMNEKSDVYSLGVVLLEVITGQPAIASSKTEKVHISDHVRSILA 793 Query: 368 NWTLEKIMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNKL 210 N + I+ + + E + I L C E +RP++ +V L ++ Sbjct: 794 NGDIRGIVDQRLR-ERYDVGSAWKMSEIALACTEHTSAQRPTMSQVVMELKQI 845
>TMK1_ARATH (P43298) Putative receptor protein kinase TMK1 precursor (EC| 2.7.11.1) Length = 942 Score = 56.6 bits (135), Expect = 5e-08 Identities = 29/116 (25%), Positives = 56/116 (48%), Gaps = 5/116 (4%) Frame = -1 Query: 542 VVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKENW 363 + G+ GY+APEY G ++ + D+YS G+I+ME+ T + + + + + K + Sbjct: 753 IAGTFGYLAPEYAVTGRVTTKVDVYSFGVILMELITGRKSLDESQPEESIHLVSWFKRMY 812 Query: 362 -----TLEKIMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNKL 210 + +K + I+L+E V + C + +RP + VN+L+ L Sbjct: 813 INKEASFKKAIDTTIDLDEETLASVHTVAELAGHCCAREPYQRPDMGHAVNILSSL 868
>RPK1_IPONI (P93194) Receptor-like protein kinase precursor (EC 2.7.11.1)| Length = 1109 Score = 56.6 bits (135), Expect = 5e-08 Identities = 32/120 (26%), Positives = 62/120 (51%), Gaps = 7/120 (5%) Frame = -1 Query: 551 TRSVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVK 372 + +V G++GYMAPE + S SD+YS G++++E+ TR + + V+ Sbjct: 976 SNTVQGTIGYMAPENAFTTVKSRESDVYSYGVVLLELITR-KKALDPSFNGETDIVGWVR 1034 Query: 371 ENWT----LEKIMSEYI---ELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNK 213 WT ++KI+ + ++ +QV +++ L+C E + KRP++ +V L + Sbjct: 1035 SVWTQTGEIQKIVDPSLLDELIDSSVMEQVTEALSLALRCAEKEVDKRPTMRDVVKQLTR 1094
>IRAK4_MOUSE (Q8R4K2) Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1)| (IRAK-4) Length = 459 Score = 56.2 bits (134), Expect = 6e-08 Identities = 35/116 (30%), Positives = 63/116 (54%), Gaps = 2/116 (1%) Frame = -1 Query: 551 TRSVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVK 372 T +VG+ YMAPE L GEI+ +SDIYS G++++E+ T ++ + + + +D + Sbjct: 345 TSRIVGTTAYMAPEAL-RGEITPKSDIYSFGVVLLELITGL--AAVDENREPQLLLDIKE 401 Query: 371 ENWTLEKIMSEYIELEEHAFD--QVEACINIGLQCVEIDQKKRPSIETIVNMLNKL 210 E EK + +Y + + D VEA + QC+ + +RP I + +L ++ Sbjct: 402 EIEDEEKTIEDYTDEKMSDADPASVEAMYSAASQCLHEKKNRRPDIAKVQQLLQEM 457
>CX32_ARATH (P27450) Probable serine/threonine-protein kinase Cx32, chloroplast| precursor (EC 2.7.11.1) Length = 419 Score = 55.8 bits (133), Expect = 8e-08 Identities = 29/118 (24%), Positives = 62/118 (52%), Gaps = 4/118 (3%) Frame = -1 Query: 551 TRSVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVK 372 T ++G+ GY APEY+ G + +SD+++ G++++EI T ++ + +D ++ Sbjct: 252 TTRIMGTYGYAAPEYMATGHLYVKSDVFAFGVVLLEIMTGLTAHNTKRPRGQESLVDWLR 311 Query: 371 ENWT----LEKIMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNKL 210 + +++IM + I+ ++ I L C+E D K RP ++ +V +L + Sbjct: 312 PELSNKHRVKQIMDKGIK-GQYTTKVATEMARITLSCIEPDPKNRPHMKEVVEVLEHI 368
>KPRO_MAIZE (P17801) Putative receptor protein kinase ZmPK1 precursor (EC| 2.7.11.1) Length = 817 Score = 53.9 bits (128), Expect = 3e-07 Identities = 35/123 (28%), Positives = 68/123 (55%), Gaps = 15/123 (12%) Frame = -1 Query: 542 VVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNS---SSTDQKHA--RKYI-- 384 V G++GY+APE++ + I+A+ D+YS G++++E+ T S TD+ H+ RK + Sbjct: 695 VRGTLGYIAPEWVSSLPITAKVDVYSYGVVLLELLTGTRVSELVGGTDEVHSMLRKLVRM 754 Query: 383 -----DGVKENWTLEKIMSEYIELEEHA---FDQVEACINIGLQCVEIDQKKRPSIETIV 228 +G +++W + Y++ + + + Q I + + C+E D+ KRP++E V Sbjct: 755 LSAKLEGEEQSW-----IDGYLDSKLNRPVNYVQARTLIKLAVSCLEEDRSKRPTMEHAV 809 Query: 227 NML 219 L Sbjct: 810 QTL 812
>BAK1_ARATH (Q94F62) BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1| precursor (EC 2.7.11.1) (BRI1-associated receptor kinase 1) (Somatic embryogenesis receptor-like kinase 3) Length = 615 Score = 53.9 bits (128), Expect = 3e-07 Identities = 30/117 (25%), Positives = 64/117 (54%), Gaps = 6/117 (5%) Frame = -1 Query: 551 TRSVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEIST-----RXMNSSSTDQKHARKY 387 T +V G++G++APEYL G+ S ++D++ G++++E+ T ++ D + Sbjct: 449 TTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGVMLLELITGQRAFDLARLANDDDVMLLDW 508 Query: 386 IDGVKENWTLEKIMSEYIELE-EHAFDQVEACINIGLQCVEIDQKKRPSIETIVNML 219 + G+ + LE ++ ++L+ + ++VE I + L C + +RP + +V ML Sbjct: 509 VKGLLKEKKLEALVD--VDLQGNYKDEEVEQLIQVALLCTQSSPMERPKMSEVVRML 563
>APK1B_ARATH (P46573) Protein kinase APK1B, chloroplast precursor (EC 2.7.11.1)| Length = 412 Score = 53.5 bits (127), Expect = 4e-07 Identities = 28/119 (23%), Positives = 60/119 (50%), Gaps = 3/119 (2%) Frame = -1 Query: 542 VVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKENW 363 ++G+ GY APEYL G ++ +SD+YS G++++E+ + +K ++ + Sbjct: 241 IMGTYGYAAPEYLATGHLTTKSDVYSYGVVLLEVLSGRRAVDKNRPPGEQKLVEWARPLL 300 Query: 362 TLEKIMSEYIELE-EHAFDQVEAC--INIGLQCVEIDQKKRPSIETIVNMLNKLPVSEE 195 ++ + I+ + + EAC + L+C+ + K RP++ +V+ L + E Sbjct: 301 ANKRKLFRVIDNRLQDQYSMEEACKVATLALRCLTFEIKLRPNMNEVVSHLEHIQTLNE 359
>APK1A_ARATH (Q06548) Protein kinase APK1A, chloroplast precursor (EC 2.7.11.1)| Length = 410 Score = 53.1 bits (126), Expect = 5e-07 Identities = 29/114 (25%), Positives = 58/114 (50%), Gaps = 3/114 (2%) Frame = -1 Query: 542 VVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKENW 363 V+G+ GY APEYL G ++ +SD+YS G++++E+ + R ++ K Sbjct: 240 VMGTHGYAAPEYLATGHLTTKSDVYSFGVVLLELLSGRRAVDKNRPSGERNLVEWAKPYL 299 Query: 362 TLEKIMSEYIELE-EHAFDQVEAC--INIGLQCVEIDQKKRPSIETIVNMLNKL 210 ++ + I+ + + EAC + L+C+ + K RP++ +V+ L + Sbjct: 300 VNKRKIFRVIDNRLQDQYSMEEACKVATLSLRCLTTEIKLRPNMSEVVSHLEHI 353
>CLV1_ARATH (Q9SYQ8) Receptor protein kinase CLAVATA1 precursor (EC 2.7.11.1)| Length = 980 Score = 52.4 bits (124), Expect = 9e-07 Identities = 32/121 (26%), Positives = 58/121 (47%), Gaps = 6/121 (4%) Frame = -1 Query: 545 SVVGSVGYMAPEYLYNGEISARSDIYSLGLIIME-ISTRXMNSSSTDQKHARKYIDGVKE 369 S+ GS GY+APEY Y ++ +SD+YS G++++E I+ + + +++ +E Sbjct: 853 SIAGSYGYIAPEYAYTLKVDEKSDVYSFGVVLLELIAGKKPVGEFGEGVDIVRWVRNTEE 912 Query: 368 NWTLEKIMSEYI-----ELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNKLPV 204 T + + L + V I + CVE + RP++ +V+ML P Sbjct: 913 EITQPSDAAIVVAIVDPRLTGYPLTSVIHVFKIAMMCVEEEAAARPTMREVVHMLTNPPK 972 Query: 203 S 201 S Sbjct: 973 S 973
>PSKR_DAUCA (Q8LPB4) Phytosulfokine receptor precursor (EC 2.7.11.1)| (Phytosulfokine LRR receptor kinase) Length = 1021 Score = 51.6 bits (122), Expect = 1e-06 Identities = 31/120 (25%), Positives = 63/120 (52%), Gaps = 3/120 (2%) Frame = -1 Query: 551 TRSVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVK 372 T +VG++GY+ PEY + + D+YS G++++E+ T + +R I V Sbjct: 902 TTDLVGTLGYIPPEYGQASVATYKGDVYSFGVVLLELLTGRRPMDVCKPRGSRDLISWVL 961 Query: 371 ENWTLEK---IMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNKLPVS 201 + T ++ I +I ++HA +++ + I +C+ + K RP+ + +V+ L + VS Sbjct: 962 QMKTEKRESEIFDPFIYDKDHA-EEMLLVLEIACRCLGENPKTRPTTQQLVSWLENIDVS 1020
>KPEL_DROME (Q05652) Probable serine/threonine-protein kinase pelle (EC| 2.7.11.1) Length = 501 Score = 49.7 bits (117), Expect = 6e-06 Identities = 29/113 (25%), Positives = 54/113 (47%), Gaps = 8/113 (7%) Frame = -1 Query: 542 VVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEIST-RXMNSSSTDQKHARKYIDGVKEN 366 V G+ Y+ PE+ ++S D+YS G++++E+ T R + + + + +D VK+ Sbjct: 384 VFGTKIYLPPEFRNFRQLSTGVDVYSFGIVLLEVFTGRQVTDRVPENETKKNLLDYVKQQ 443 Query: 365 WTLEKIMSEYIELEEH-------AFDQVEACINIGLQCVEIDQKKRPSIETIV 228 W ++ LE+H D I GL C +D + RPS+ ++ Sbjct: 444 WRQNRMEL----LEKHLAAPMGKELDMCMCAIEAGLHCTALDPQDRPSMNAVL 492
>RLCK7_ARATH (Q9LQQ8) Probable serine/threonine-protein kinase RLCKVII (EC| 2.7.11.1) Length = 423 Score = 48.9 bits (115), Expect = 9e-06 Identities = 29/119 (24%), Positives = 58/119 (48%), Gaps = 4/119 (3%) Frame = -1 Query: 542 VVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGV---- 375 V+G+ GY AP+Y G+++ +SDIYS G++++E+ T +T + + + Sbjct: 267 VMGTYGYCAPDYAMTGQLTFKSDIYSFGVVLLELITGRKAIDNTKTRKDQNLVGWARPLF 326 Query: 374 KENWTLEKIMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNKLPVSE 198 K+ K++ ++ ++ + + I CV+ RP + +V LN L S+ Sbjct: 327 KDRRNFPKMVDPLLQ-GQYPVRGLYQALAISAMCVQEQPTMRPVVSDVVLALNFLASSK 384
>BRI1_LYCPE (Q8L899) Systemin receptor SR160 precursor (EC 2.7.11.1)| (Brassinosteroid LRR receptor kinase) Length = 1207 Score = 47.8 bits (112), Expect = 2e-05 Identities = 30/122 (24%), Positives = 59/122 (48%), Gaps = 10/122 (8%) Frame = -1 Query: 545 SVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTD----------QKHA 396 ++ G+ GY+ PEY + S + D+YS G++++E+ T + S D + HA Sbjct: 1050 TLAGTPGYVPPEYYQSFRCSTKGDVYSYGVVLLELLTGKQPTDSADFGDNNLVGWVKLHA 1109 Query: 395 RKYIDGVKENWTLEKIMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLN 216 + I V + L++ S IEL +H + + C++ KRP++ ++ M Sbjct: 1110 KGKITDVFDRELLKEDASIEIELLQH--------LKVACACLDDRHWKRPTMIQVMAMFK 1161 Query: 215 KL 210 ++ Sbjct: 1162 EI 1163
>BRI1_LYCES (Q8GUQ5) Brassinosteroid LRR receptor kinase precursor (EC 2.7.11.1)| (tBRI1) (Altered brassinolide sensitivity 1) (Systemin receptor SR160) Length = 1207 Score = 47.8 bits (112), Expect = 2e-05 Identities = 30/122 (24%), Positives = 59/122 (48%), Gaps = 10/122 (8%) Frame = -1 Query: 545 SVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTD----------QKHA 396 ++ G+ GY+ PEY + S + D+YS G++++E+ T + S D + HA Sbjct: 1050 TLAGTPGYVPPEYYQSFRCSTKGDVYSYGVVLLELLTGKQPTDSADFGDNNLVGWVKLHA 1109 Query: 395 RKYIDGVKENWTLEKIMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLN 216 + I V + L++ S IEL +H + + C++ KRP++ ++ M Sbjct: 1110 KGKITDVFDRELLKEDASIEIELLQH--------LKVACACLDDRHWKRPTMIQVMAMFK 1161 Query: 215 KL 210 ++ Sbjct: 1162 EI 1163
>BRL2_ARATH (Q9ZPS9) Serine/threonine-protein kinase BRI1-like 2 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 2) (Protein VASCULAR HIGHWAY 1) Length = 1143 Score = 47.8 bits (112), Expect = 2e-05 Identities = 35/139 (25%), Positives = 71/139 (51%), Gaps = 18/139 (12%) Frame = -1 Query: 545 SVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTD------------QK 402 ++ G+ GY+ PEY + +A+ D+YS+G++++EI + + + + Sbjct: 1002 TLAGTPGYVPPEYYQSFRCTAKGDVYSIGVVMLEILSGKRPTDKEEFGDTNLVGWSKMKA 1061 Query: 401 HARKYIDGVKENWTLEKIMSEYIELEEHAFD------QVEACINIGLQCVEIDQKKRPSI 240 K+++ + E+ L++ SE + E+ F+ ++ + I L+CV+ KRP++ Sbjct: 1062 REGKHMEVIDED-LLKEGSSESLN-EKEGFEGGVIVKEMLRYLEIALRCVDDFPSKRPNM 1119 Query: 239 ETIVNMLNKLPVSEEVSHS 183 +V L +L SE SHS Sbjct: 1120 LQVVASLRELRGSENNSHS 1138
>M3LK7_DROME (P83104) Putative mitogen-activated protein kinase kinase kinase| 7-like (EC 2.7.11.25) Length = 393 Score = 46.6 bits (109), Expect = 5e-05 Identities = 29/110 (26%), Positives = 58/110 (52%), Gaps = 2/110 (1%) Frame = -1 Query: 536 GSVGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKENWTL 357 G++ YMAPE + + + +A+ D+YS G+++ E+ TR + S +++ + + Sbjct: 168 GTLRYMAPEAIKHLKYTAKCDVYSFGIMLWELMTRQLPYS---------HLENPNSQYAI 218 Query: 356 EKIMS--EYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNK 213 K +S E + +E D E + C++I+ +KRPS++ I L + Sbjct: 219 MKAISSGEKLPMEAVRSDCPEGIKQLMECCMDINPEKRPSMKEIEKFLGE 268
>SRC64_DROME (P00528) Tyrosine-protein kinase Src64B (EC 2.7.10.2) (Dsrc64)| Length = 552 Score = 45.4 bits (106), Expect = 1e-04 Identities = 28/115 (24%), Positives = 55/115 (47%) Frame = -1 Query: 530 VGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKENWTLEK 351 V + APE + G+ S +SD++S G+++ME+ T H+R+ I+ ++ + + K Sbjct: 444 VKWTAPEAIIYGKFSIKSDVWSYGILLMELFT--YGQVPYPGMHSREVIENIERGFRMPK 501 Query: 350 IMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNKLPVSEEVSH 186 + Y + + LQC + +KRP+ E + + V+ EV + Sbjct: 502 PTNHYFP---------DNIYQLLLQCWDAVPEKRPTFEFLNHYFESFSVTSEVPY 547
>BRI1_ARATH (O22476) BRASSINOSTEROID INSENSITIVE 1 precursor (EC 2.7.11.1)| (AtBRI1) (Brassinosteroid LRR receptor kinase) Length = 1196 Score = 45.1 bits (105), Expect = 1e-04 Identities = 27/122 (22%), Positives = 61/122 (50%), Gaps = 10/122 (8%) Frame = -1 Query: 545 SVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTD----------QKHA 396 ++ G+ GY+ PEY + S + D+YS G++++E+ T + S D ++HA Sbjct: 1045 TLAGTPGYVPPEYYQSFRCSTKGDVYSYGVVLLELLTGKRPTDSPDFGDNNLVGWVKQHA 1104 Query: 395 RKYIDGVKENWTLEKIMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLN 216 + I V + +++ + IEL +H + + + C++ +RP++ ++ M Sbjct: 1105 KLRISDVFDPELMKEDPALEIELLQH--------LKVAVACLDDRAWRRPTMVQVMAMFK 1156 Query: 215 KL 210 ++ Sbjct: 1157 EI 1158
>MLTK_MOUSE (Q9ESL4) Mitogen-activated protein kinase kinase kinase MLT (EC| 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper-and sterile alpha motif kinase ZAK) (Sterile alpha motif- and leucine zipper-containing kinase AZK) ( Length = 802 Score = 44.7 bits (104), Expect = 2e-04 Identities = 30/112 (26%), Positives = 57/112 (50%) Frame = -1 Query: 545 SVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKEN 366 S+VG+ +MAPE + + +S D YS G+++ E+ TR + K ++G++ Sbjct: 165 SLVGTFPWMAPEVIQSLPVSETCDTYSYGVVLWEMLTREV---------PFKGLEGLQVA 215 Query: 365 WTLEKIMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNKL 210 W + + +E + + ++ QC E D KKRPS + I+++L + Sbjct: 216 WLVVE-KNERLTIPSSCPRSFAELLH---QCWEADAKKRPSFKQIISILESM 263
>MLTK_HUMAN (Q9NYL2) Mitogen-activated protein kinase kinase kinase MLT (EC| 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper-and sterile alpha motif-containing kinase) (Sterile alpha motif- and leucine zipper-containing kinase Length = 800 Score = 44.7 bits (104), Expect = 2e-04 Identities = 30/112 (26%), Positives = 57/112 (50%) Frame = -1 Query: 545 SVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKEN 366 S+VG+ +MAPE + + +S D YS G+++ E+ TR + K ++G++ Sbjct: 165 SLVGTFPWMAPEVIQSLPVSETCDTYSYGVVLWEMLTREV---------PFKGLEGLQVA 215 Query: 365 WTLEKIMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNKL 210 W + + +E + + ++ QC E D KKRPS + I+++L + Sbjct: 216 WLVVE-KNERLTIPSSCPRSFAELLH---QCWEADAKKRPSFKQIISILESM 263
>PBS1_ARATH (Q9FE20) Serine/threonine-protein kinase PBS1 (EC 2.7.11.1)| (AvrPphB susceptible protein 1) Length = 456 Score = 44.3 bits (103), Expect = 2e-04 Identities = 16/36 (44%), Positives = 27/36 (75%) Frame = -1 Query: 542 VVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEIST 435 V+G+ GY APEY G+++ +SD+YS G++ +E+ T Sbjct: 250 VMGTYGYCAPEYAMTGQLTVKSDVYSFGVVFLELIT 285
>CAD96_DROME (Q9VBW3) Tyrosine kinase receptor Cad96Ca precursor (EC 2.7.10.1)| (Cadherin 96Ca) (Tyrosine kinase receptor HD-14) Length = 773 Score = 43.5 bits (101), Expect = 4e-04 Identities = 33/107 (30%), Positives = 53/107 (49%) Frame = -1 Query: 530 VGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKENWTLEK 351 + +MA E LY+ S +SDI+S G+++ EI T + S+ A + V++ + LEK Sbjct: 651 IRWMATESLYDNIFSVKSDIWSFGILMWEIVT--LGSTPYPGISAADVMRKVRDGYRLEK 708 Query: 350 IMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNKL 210 EH ++ NI C D ++RP I+ ML+KL Sbjct: 709 --------PEHCRREL---YNIMYYCWSHDPQERPLFAEIIQMLDKL 744
>NORK_PEA (Q8LKZ1) Nodulation receptor kinase precursor (EC 2.7.11.1)| Length = 924 Score = 42.7 bits (99), Expect = 7e-04 Identities = 32/122 (26%), Positives = 60/122 (49%), Gaps = 7/122 (5%) Frame = -1 Query: 542 VVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEI-------STRXMNSSSTDQKHARKYI 384 V G+ GY+ PEY ++S +SD++S G++++EI + + + + A+ YI Sbjct: 758 VRGTAGYLDPEYYKTQQLSEKSDVFSFGVVLLEIVSGREPLNIKRPRVEWSLVEWAKPYI 817 Query: 383 DGVKENWTLEKIMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNKLPV 204 K +++I+ I+ HA + + + + LQC+E RP + IV L + Sbjct: 818 RASK----VDEIVDPGIKGGYHA-EALWRVVEVALQCLEPYSTYRPCMVDIVRELEDALI 872 Query: 203 SE 198 E Sbjct: 873 IE 874
>NORK_MEDTR (Q8L4H4) Nodulation receptor kinase precursor (EC 2.7.11.1) (Does not| make infections protein 2) (Symbiosis receptor-like kinase) (MtSYMRK) Length = 925 Score = 42.7 bits (99), Expect = 7e-04 Identities = 32/122 (26%), Positives = 60/122 (49%), Gaps = 7/122 (5%) Frame = -1 Query: 542 VVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEI-------STRXMNSSSTDQKHARKYI 384 V G+ GY+ PEY ++S +SD++S G++++EI + + + + A+ YI Sbjct: 759 VRGTAGYLDPEYYKTQQLSEKSDVFSFGVVLLEIVSGREPLNIKRPRIEWSLVEWAKPYI 818 Query: 383 DGVKENWTLEKIMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNKLPV 204 K +++I+ I+ HA + + + + LQC+E RP + IV L + Sbjct: 819 RASK----VDEIVDPGIKGGYHA-EALWRVVEVALQCLEPYSTYRPCMVDIVRELEDALI 873 Query: 203 SE 198 E Sbjct: 874 IE 875
>PSKR_ARATH (Q9ZVR7) Putative phytosulfokine receptor precursor (EC 2.7.11.1)| (Phytosulfokine LRR receptor kinase) Length = 1008 Score = 42.7 bits (99), Expect = 7e-04 Identities = 27/112 (24%), Positives = 53/112 (47%), Gaps = 3/112 (2%) Frame = -1 Query: 542 VVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGV---K 372 +VG++GY+ PEY + + D+YS G++++E+ T K R I V K Sbjct: 896 LVGTLGYIPPEYGQASVATYKGDVYSFGVVLLELLTDKRPVDMCKPKGCRDLISWVVKMK 955 Query: 371 ENWTLEKIMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLN 216 ++ I +E+ + + I C+ + K+RP+ + +V+ L+ Sbjct: 956 HESRASEVFDPLIYSKENDKEMFRV-LEIACLCLSENPKQRPTTQQLVSWLD 1006
>PKN2_BACSU (O34507) Probable serine/threonine-protein kinase yloP (EC| 2.7.11.1) Length = 648 Score = 42.0 bits (97), Expect = 0.001 Identities = 18/39 (46%), Positives = 28/39 (71%) Frame = -1 Query: 551 TRSVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEIST 435 T SV+GSV Y++PE G + +SDIY+LG+++ E+ T Sbjct: 167 TNSVLGSVHYLSPEQARGGLATKKSDIYALGIVLFELLT 205
>TESK2_MOUSE (Q8VCT9) Dual specificity testis-specific protein kinase 2 (EC| 2.7.12.1) (Testicular protein kinase 2) Length = 570 Score = 42.0 bits (97), Expect = 0.001 Identities = 33/120 (27%), Positives = 56/120 (46%), Gaps = 4/120 (3%) Frame = -1 Query: 545 SVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKEN 366 +VVGS +MAPE L + + ++D++S G+I+ EI R D + + EN Sbjct: 215 AVVGSPFWMAPEVLRDEPYNEKADVFSYGIILCEIIARI----QADPDYLPR-----TEN 265 Query: 365 WTLEKIMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIE----TIVNMLNKLPVSE 198 + L +Y + D + + C +D K RPS E T+ ++++LP E Sbjct: 266 FGL-----DYDAFQNMVGDCPSDFLQLTFNCCNMDPKLRPSFEEIGKTLKEIMSRLPEEE 320
>PKNB_MYCLE (P54744) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 622 Score = 41.2 bits (95), Expect = 0.002 Identities = 17/39 (43%), Positives = 26/39 (66%) Frame = -1 Query: 551 TRSVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEIST 435 T +V+G+ Y++PE + ARSD+YSLG ++ EI T Sbjct: 172 TAAVIGTAQYLSPEQARGDSVDARSDVYSLGCVLYEILT 210
>FLT3_MOUSE (Q00342) FL cytokine receptor precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor flk-2) (Fetal liver kinase 2) (Tyrosine-protein kinase FLT3) Length = 992 Score = 41.2 bits (95), Expect = 0.002 Identities = 29/113 (25%), Positives = 53/113 (46%), Gaps = 1/113 (0%) Frame = -1 Query: 530 VGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKENWTLEK 351 V +MAPE L+ G + +SD++S G+++ EI + +N G+ + K Sbjct: 855 VKWMAPESLFEGIYTIKSDVWSYGILLWEIFSLGVNP-----------YPGIPVDANFYK 903 Query: 350 IMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLN-KLPVSEE 195 ++ ++E+ F E + C D +KRPS + + L +L +EE Sbjct: 904 LIQSGFKMEQ-PFYATEGIYFVMQSCWAFDSRKRPSFPNLTSFLGCQLAEAEE 955
>PKNB_MYCTU (P0A5S4) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 626 Score = 40.8 bits (94), Expect = 0.003 Identities = 16/39 (41%), Positives = 26/39 (66%) Frame = -1 Query: 551 TRSVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEIST 435 T +V+G+ Y++PE + ARSD+YSLG ++ E+ T Sbjct: 173 TAAVIGTAQYLSPEQARGDSVDARSDVYSLGCVLYEVLT 211
>PKNB_MYCBO (P0A5S5) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 626 Score = 40.8 bits (94), Expect = 0.003 Identities = 16/39 (41%), Positives = 26/39 (66%) Frame = -1 Query: 551 TRSVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEIST 435 T +V+G+ Y++PE + ARSD+YSLG ++ E+ T Sbjct: 173 TAAVIGTAQYLSPEQARGDSVDARSDVYSLGCVLYEVLT 211
>TESK2_RAT (Q924U5) Dual specificity testis-specific protein kinase 2 (EC| 2.7.12.1) (Testicular protein kinase 2) Length = 570 Score = 40.4 bits (93), Expect = 0.003 Identities = 31/112 (27%), Positives = 51/112 (45%) Frame = -1 Query: 545 SVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKEN 366 +VVGS +MAPE L + + ++D++S G+I+ EI R D + + EN Sbjct: 215 AVVGSPFWMAPEVLRDEPYNEKADVFSYGIILCEIIARI----QADPDYLPR-----TEN 265 Query: 365 WTLEKIMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNKL 210 + L +Y + D + + C +D K RPS E I L ++ Sbjct: 266 FGL-----DYDAFQHMVGDCPSDFLQLTFNCCNMDPKLRPSFEEIGKTLEEI 312
>IRAK3_HUMAN (Q9Y616) Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1)| (IRAK-3) (IL-1 receptor-associated kinase M) (IRAK-M) Length = 596 Score = 40.4 bits (93), Expect = 0.003 Identities = 31/113 (27%), Positives = 52/113 (46%), Gaps = 5/113 (4%) Frame = -1 Query: 524 YMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKH--ARKYIDGVKENWTLEK 351 YM EY+ G++S ++D+YS G++IME+ T D KH R + + E L+ Sbjct: 340 YMPEEYIRQGKLSIKTDVYSFGIVIMEVLT-GCRVVLDDPKHIQLRDLLRELMEKRGLDS 398 Query: 350 IMS---EYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNKLPVS 201 +S + + F C + +C K RPS++ ++N L S Sbjct: 399 CLSFLDKKVPPCPRNFSAKLFC--LAGRCAATRAKLRPSMDEVLNTLESTQAS 449
>FLT3_HUMAN (P36888) FL cytokine receptor precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor FLT3) (Stem cell tyrosine kinase 1) (STK-1) (CD135 antigen) Length = 993 Score = 40.4 bits (93), Expect = 0.003 Identities = 33/131 (25%), Positives = 58/131 (44%), Gaps = 1/131 (0%) Frame = -1 Query: 530 VGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKENWTLEK 351 V +MAPE L+ G + +SD++S G+++ EI + +N G+ + K Sbjct: 852 VKWMAPESLFEGIYTIKSDVWSYGILLWEIFSLGVNP-----------YPGIPVDANFYK 900 Query: 350 IMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLN-KLPVSEEVSHSM*A 174 ++ ++++ F E I C D +KRPS + + L +L +EE + Sbjct: 901 LIQNGFKMDQ-PFYATEEIYIIMQSCWAFDSRKRPSFPNLTSFLGCQLADAEEAMY---- 955 Query: 173 QNFPLFSERCP 141 QN CP Sbjct: 956 QNVDGRVSECP 966
>PKND_CHLMU (Q9PK92) Serine/threonine-protein kinase pknD (EC 2.7.11.1)| Length = 934 Score = 40.4 bits (93), Expect = 0.003 Identities = 18/36 (50%), Positives = 26/36 (72%) Frame = -1 Query: 542 VVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEIST 435 +VG+ YMAPE L E S ++DIY+LGLI+ ++ T Sbjct: 196 IVGTPDYMAPESLLGAEASEKTDIYALGLILYQMLT 231
>GUC2C_PIG (P55204) Heat-stable enterotoxin receptor precursor (GC-C)| (Intestinal guanylate cyclase) (EC 4.6.1.2) (STA receptor) Length = 1073 Score = 40.0 bits (92), Expect = 0.004 Identities = 31/105 (29%), Positives = 49/105 (46%) Frame = -1 Query: 524 YMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKENWTLEKIM 345 + APE+L +S + D+YS G+I EI R + + ++ I V EN K Sbjct: 646 WTAPEHLRRASVSQKGDVYSYGIIAQEIILRRETFYTLSCRDQKEKIFRV-ENSNGVKPF 704 Query: 344 SEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNKL 210 + LE ++E + + C E D +KRP + I N L K+ Sbjct: 705 RPDLFLETAEEKELEVYLLV-KNCWEEDPEKRPDFKKIENTLAKI 748
>BRL3_ARATH (Q9LJF3) Serine/threonine-protein kinase BRI1-like 3 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 3) Length = 1164 Score = 40.0 bits (92), Expect = 0.004 Identities = 29/116 (25%), Positives = 56/116 (48%), Gaps = 4/116 (3%) Frame = -1 Query: 545 SVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKEN 366 ++ G+ GY+ PEY + +A+ D+YS G+I++E+ + + + K+ Sbjct: 1021 TLAGTPGYVPPEYYQSFRCTAKGDVYSYGVILLELLSGKKPIDPEEFGEDNNLVGWAKQL 1080 Query: 365 WTLEKIMSEYI--ELEEHAFDQVEAC--INIGLQCVEIDQKKRPSIETIVNMLNKL 210 + EK +E + EL VE + I QC++ KRP++ ++ M +L Sbjct: 1081 YR-EKRGAEILDPELVTDKSGDVELLHYLKIASQCLDDRPFKRPTMIQVMTMFKEL 1135
>BRL1_ARATH (Q9ZWC8) Serine/threonine-protein kinase BRI1-like 1 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 1) Length = 1166 Score = 40.0 bits (92), Expect = 0.004 Identities = 24/125 (19%), Positives = 59/125 (47%), Gaps = 3/125 (2%) Frame = -1 Query: 545 SVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKEN 366 ++ G+ GY+ PEY + +A+ D+YS G+I++E+ + + + K+ Sbjct: 1023 TLAGTPGYVPPEYYQSFRCTAKGDVYSYGVILLELLSGKKPIDPGEFGEDNNLVGWAKQL 1082 Query: 365 WTLEK---IMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNKLPVSEE 195 + ++ I+ + ++ ++ + I QC++ KRP++ ++ M ++ E Sbjct: 1083 YREKRGAEILDPELVTDKSGDVELFHYLKIASQCLDDRPFKRPTMIQLMAMFKEMKADTE 1142 Query: 194 VSHSM 180 S+ Sbjct: 1143 EDESL 1147
>SPKA_SYNY3 (Q9FAB3) Serine/threonine-protein kinase A (EC 2.7.11.1)| Length = 521 Score = 40.0 bits (92), Expect = 0.004 Identities = 17/42 (40%), Positives = 30/42 (71%) Frame = -1 Query: 551 TRSVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXM 426 T++ +G++ Y +PE + E+ +RSDIYSLG+++ E+ T M Sbjct: 185 TQAFMGTLAYCSPEQMEGKELDSRSDIYSLGVMMYEMLTGEM 226
>NEK9_XENLA (Q7ZZC8) Serine/threonine-protein kinase Nek9 (EC 2.7.11.1)| (NimA-related protein kinase 9) (XNek9) (Nercc1 kinase) Length = 944 Score = 39.7 bits (91), Expect = 0.006 Identities = 28/104 (26%), Positives = 52/104 (50%) Frame = -1 Query: 539 VGSVGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKENWT 360 VG++ YM+PE + S +SDI+++G ++ E+ T +T+ + I V+ NW Sbjct: 194 VGTLYYMSPEICQGVKYSFKSDIWAVGCVLYELLTLTRTFDATNPLNLCVKI--VQGNWA 251 Query: 359 LEKIMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIV 228 + L+ + Q I + C+E D +KRP+ + I+ Sbjct: 252 --------VGLDNTVYTQ--ELIEVVHACLEQDPEKRPTADEIL 285
>EXS_ARATH (Q9LYN8) Leucine-rich repeat receptor protein kinase EXS precursor| (EC 2.7.11.1) (Extra sporogenous cells protein) (EXCESS MICROSPOROCYTES1 protein) Length = 1192 Score = 39.3 bits (90), Expect = 0.007 Identities = 26/118 (22%), Positives = 55/118 (46%), Gaps = 7/118 (5%) Frame = -1 Query: 542 VVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKENW 363 + G+ GY+ PEY + + + D+YS G+I++E+ T + D K + G W Sbjct: 1079 IAGTFGYIPPEYGQSARATTKGDVYSFGVILLELVT-GKEPTGPDFKESE---GGNLVGW 1134 Query: 362 TLEKI-MSEYIELEEHAFDQVE------ACINIGLQCVEIDQKKRPSIETIVNMLNKL 210 ++KI + +++ + V + I + C+ KRP++ ++ L ++ Sbjct: 1135 AIQKINQGKAVDVIDPLLVSVALKNSQLRLLQIAMLCLAETPAKRPNMLDVLKALKEI 1192
>CRI4_MAIZE (O24585) Putative receptor protein kinase CRINKLY4 precursor (EC| 2.7.11.1) Length = 901 Score = 39.3 bits (90), Expect = 0.007 Identities = 25/111 (22%), Positives = 55/111 (49%), Gaps = 5/111 (4%) Frame = -1 Query: 536 GSVGYMAPEYLYNGEISARSDIYSLGLIIMEI--STRXMNSSSTDQKHARKYIDGVKEN- 366 G++GY+ PEY ++ +SD+YS G++++EI + ++ + + +K Sbjct: 673 GTLGYLDPEYYRLHYLTTKSDVYSFGVVLLEILSGRKAIDMQFEEGNIVEWAVPLIKAGD 732 Query: 365 --WTLEKIMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNML 219 L+ ++S +LE ++ ++ +CV + K RPS++ + L Sbjct: 733 IFAILDPVLSPPSDLE-----ALKKIASVACKCVRMRGKDRPSMDKVTTAL 778
>PKND_CHLTR (O84303) Serine/threonine-protein kinase pknD (EC 2.7.11.1)| Length = 934 Score = 39.3 bits (90), Expect = 0.007 Identities = 18/36 (50%), Positives = 26/36 (72%) Frame = -1 Query: 542 VVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEIST 435 +VG+ YMAPE L E S ++DIY+LGLI+ ++ T Sbjct: 196 IVGTPDYMAPESLLGVEASEKTDIYALGLILYQMLT 231
>BYR1_SCHPO (P10506) Protein kinase byr1 (EC 2.7.12.2) (MAPK kinase) (MAPKK)| Length = 340 Score = 39.3 bits (90), Expect = 0.007 Identities = 16/41 (39%), Positives = 31/41 (75%) Frame = -1 Query: 548 RSVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXM 426 ++ VG+ YM+PE + G+ + +SDI+SLG+ I+E++T+ + Sbjct: 217 QTFVGTSTYMSPERIRGGKYTVKSDIWSLGISIIELATQEL 257
>FIN1_SCHPO (O13839) G2-specific protein kinase fin1 (EC 2.7.11.1)| Length = 722 Score = 38.9 bits (89), Expect = 0.010 Identities = 17/37 (45%), Positives = 27/37 (72%) Frame = -1 Query: 551 TRSVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEI 441 T+S VG+ YM+PE + + SA+SD+++LG +I EI Sbjct: 183 TQSYVGTPYYMSPEIIRSSPYSAKSDVWALGCVIFEI 219
>PKN2_CLOAB (Q97IC2) Probable serine/threonine protein kinase CAC1728 (EC| 2.7.11.1) Length = 657 Score = 38.9 bits (89), Expect = 0.010 Identities = 16/39 (41%), Positives = 25/39 (64%) Frame = -1 Query: 551 TRSVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEIST 435 T VVGS Y++PE + R+DIYS G+++ E++T Sbjct: 166 TNKVVGSAHYLSPEQAQGIPVDCRTDIYSFGIVLYEMAT 204
>TESK2_HUMAN (Q96S53) Dual specificity testis-specific protein kinase 2 (EC| 2.7.12.1) (Testicular protein kinase 2) Length = 571 Score = 38.5 bits (88), Expect = 0.013 Identities = 32/121 (26%), Positives = 56/121 (46%), Gaps = 4/121 (3%) Frame = -1 Query: 545 SVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKEN 366 +VVGS +MAPE L + + ++D++S G+I+ EI R D + + EN Sbjct: 215 AVVGSPFWMAPEVLRDEPYNEKADVFSYGIILCEIIARI----QADPDYLPR-----TEN 265 Query: 365 WTLEKIMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSI----ETIVNMLNKLPVSE 198 + L +Y + D + + C +D K RPS +T+ +L++L E Sbjct: 266 FGL-----DYDAFQHMVGDCPPDFLQLTFNCCNMDPKLRPSFVEIGKTLEEILSRLQEEE 320 Query: 197 E 195 + Sbjct: 321 Q 321
>IRAK3_MOUSE (Q8K4B2) Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1)| (IRAK-3) (IL-1 receptor-associated kinase M) (IRAK-M) Length = 609 Score = 38.5 bits (88), Expect = 0.013 Identities = 14/30 (46%), Positives = 22/30 (73%) Frame = -1 Query: 524 YMAPEYLYNGEISARSDIYSLGLIIMEIST 435 YM EY+ G +S ++D+YS G++IME+ T Sbjct: 353 YMPEEYIRQGRLSVKTDVYSFGIVIMEVLT 382
>PKNL_MYCTU (O53510) Probable serine/threonine-protein kinase pknL (EC| 2.7.11.1) Length = 399 Score = 38.5 bits (88), Expect = 0.013 Identities = 14/39 (35%), Positives = 27/39 (69%) Frame = -1 Query: 551 TRSVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEIST 435 T ++G+ Y++PE + +G RSD+YS+G+++ E+ T Sbjct: 175 TGVILGTAAYLSPEQVRDGNADPRSDVYSVGVLVYELLT 213
>PKNL_MYCBO (Q7TYY6) Probable serine/threonine-protein kinase pknL (EC| 2.7.11.1) Length = 399 Score = 38.5 bits (88), Expect = 0.013 Identities = 14/39 (35%), Positives = 27/39 (69%) Frame = -1 Query: 551 TRSVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEIST 435 T ++G+ Y++PE + +G RSD+YS+G+++ E+ T Sbjct: 175 TGVILGTAAYLSPEQVRDGNADPRSDVYSVGVLVYELLT 213
>CTR1_ARATH (Q05609) Serine/threonine-protein kinase CTR1 (EC 2.7.11.1)| Length = 821 Score = 38.5 bits (88), Expect = 0.013 Identities = 31/114 (27%), Positives = 54/114 (47%) Frame = -1 Query: 551 TRSVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVK 372 ++S G+ +MAPE L + + +SD+YS G+I+ E++T + + + G K Sbjct: 708 SKSAAGTPEWMAPEVLRDEPSNEKSDVYSFGVILWELATLQQPWGNLNPAQVVAAV-GFK 766 Query: 371 ENWTLEKIMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNKL 210 + +E+ + QV A I C + KRPS TI+++L L Sbjct: 767 ---------CKRLEIPRNLNPQVAAIIE---GCWTNEPWKRPSFATIMDLLRPL 808
>GUC2C_CAVPO (P70106) Heat-stable enterotoxin receptor precursor (GC-C)| (Intestinal guanylate cyclase) (EC 4.6.1.2) (STA receptor) (Guanylyl cyclase C) Length = 1076 Score = 38.5 bits (88), Expect = 0.013 Identities = 29/106 (27%), Positives = 48/106 (45%), Gaps = 1/106 (0%) Frame = -1 Query: 524 YMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKENWTLEKIM 345 + APE+L S + D+YS G+I EI R + + ++ I V+ L+ Sbjct: 649 WTAPEHLRQASTSQKGDVYSFGIIAQEIIMRRETFYTLSCRDQKEKIFRVEHPDGLKPFR 708 Query: 344 SE-YIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNKL 210 + ++E E +V + C E D +KRP + I N L K+ Sbjct: 709 PDLFLETAEEKELEVFLLVK---NCWEEDPEKRPDFKKIENTLAKI 751
>NEK7_MOUSE (Q9ES74) Serine/threonine-protein kinase Nek7 (EC 2.7.11.1)| (NimA-related protein kinase 7) Length = 302 Score = 38.5 bits (88), Expect = 0.013 Identities = 29/114 (25%), Positives = 57/114 (50%), Gaps = 2/114 (1%) Frame = -1 Query: 545 SVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKEN 366 S+VG+ YM+PE ++ + +SDI+SLG ++ E++ + Y D + Sbjct: 195 SLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAA----------LQSPFYGDKMNLY 244 Query: 365 WTLEKI-MSEYIEL-EEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNKL 210 +KI +Y L +H +++ +NI C+ D +KRP I + ++ ++ Sbjct: 245 SLCKKIEQCDYPPLPSDHYSEELRQLVNI---CINPDPEKRPDIAYVYDVAKRM 295
>PK1_STRTO (Q9KIG4) Serine/threonine-protein kinase PK-1 (EC 2.7.11.1)| (stoPK-1) Length = 641 Score = 38.1 bits (87), Expect = 0.017 Identities = 15/39 (38%), Positives = 27/39 (69%) Frame = -1 Query: 551 TRSVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEIST 435 T +V+G+V Y+APE + +G R D+Y+ G+++ E+ T Sbjct: 173 TGTVLGTVSYLAPEQIEHGTADPRVDVYACGILLYEMLT 211
>INSR_HUMAN (P06213) Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220| antigen) [Contains: Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1382 Score = 38.1 bits (87), Expect = 0.017 Identities = 33/132 (25%), Positives = 60/132 (45%), Gaps = 19/132 (14%) Frame = -1 Query: 530 VGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKENWTLEK 351 V +MAPE L +G + SD++S G+++ EI++ A + G+ L+ Sbjct: 1200 VRWMAPESLKDGVFTTSSDMWSFGVVLWEITSL-----------AEQPYQGLSNEQVLKF 1248 Query: 350 IMSE-YIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNML--------------- 219 +M Y++ ++ ++V + + C + + K RP+ IVN+L Sbjct: 1249 VMDGGYLDQPDNCPERVTDLMRM---CWQFNPKMRPTFLEIVNLLKDDLHPSFPEVSFFH 1305 Query: 218 ---NKLPVSEEV 192 NK P SEE+ Sbjct: 1306 SEENKAPESEEL 1317
>PKNX_STRCO (Q9XA16) Probable serine/threonine-protein kinase SCO3848 (EC| 2.7.11.1) Length = 673 Score = 38.1 bits (87), Expect = 0.017 Identities = 15/39 (38%), Positives = 26/39 (66%) Frame = -1 Query: 551 TRSVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEIST 435 T +V+G+ Y++PE ++ ARSD+YS G ++ E+ T Sbjct: 173 TAAVIGTAQYLSPEQAKGEQVDARSDLYSTGCLLYELLT 211
>CI096_HUMAN (Q8NE28) Protein kinase-like protein C9orf96| Length = 680 Score = 37.7 bits (86), Expect = 0.022 Identities = 30/101 (29%), Positives = 54/101 (53%) Frame = -1 Query: 524 YMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKENWTLEKIM 345 +MAPE L N S +SDI+SLG II+++++ T+ H RK + + +L+ ++ Sbjct: 201 WMAPEAL-NFSFSQKSDIWSLGCIILDMTSCSF-MDGTEAMHLRKSLR--QSPGSLKAVL 256 Query: 344 SEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNM 222 +EE VE N+ ++ID R +I+ +V++ Sbjct: 257 K---TMEEKQIPDVETFRNLLPLMLQIDPSDRITIKDVVHI 294
>GUC2C_HUMAN (P25092) Heat-stable enterotoxin receptor precursor (GC-C)| (Intestinal guanylate cyclase) (EC 4.6.1.2) (STA receptor) (hSTAR) Length = 1073 Score = 37.7 bits (86), Expect = 0.022 Identities = 28/106 (26%), Positives = 48/106 (45%), Gaps = 1/106 (0%) Frame = -1 Query: 524 YMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKENWTLEKIM 345 + APE+L IS + D+YS G+I EI R + + + I V+ + ++ Sbjct: 646 WTAPEHLRQANISQKGDVYSYGIIAQEIILRKETFYTLSCRDRNEKIFRVENSNGMKPFR 705 Query: 344 SE-YIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNKL 210 + ++E E +V + C E D +KRP + I L K+ Sbjct: 706 PDLFLETAEEKELEVYLLVK---NCWEEDPEKRPDFKKIETTLAKI 748
>LIMK1_CHICK (Q8QFP8) LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1) (chLIMK1)| Length = 662 Score = 37.4 bits (85), Expect = 0.028 Identities = 31/113 (27%), Positives = 50/113 (44%), Gaps = 1/113 (0%) Frame = -1 Query: 545 SVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYID-GVKE 369 +VVG+ +MAPE + + DI+S G+++ EI R S D + + D G+ Sbjct: 515 TVVGNPYWMAPEMINGRSYDEKVDIFSFGIVLCEIIGRV----SADPDYLPRTTDFGLNV 570 Query: 368 NWTLEKIMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNKL 210 LE+ +F + AC C ++D +KRPS + L L Sbjct: 571 RGFLERYCPPAC---PPSFFPIAAC------CCDLDPEKRPSFSKLEQWLETL 614
>KFMS_FSVMD (P00545) Tyrosine-protein kinase transforming protein fms (EC| 2.7.10.1) Length = 978 Score = 37.4 bits (85), Expect = 0.028 Identities = 24/106 (22%), Positives = 53/106 (50%) Frame = -1 Query: 530 VGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKENWTLEK 351 V +MAPE +++ + +SD++S G+++ EI + +N G+ N K Sbjct: 851 VKWMAPESIFDCVYTVQSDVWSYGILLWEIFSLGLNP-----------YPGILVNSKFYK 899 Query: 350 IMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNK 213 ++ + ++ + AF + +I C ++ +RP+ + I ++L K Sbjct: 900 LVKDGYQMAQPAF-APKNIYSIMQACWALEPTRRPTFQQICSLLQK 944
>MP2K2_CHICK (Q90891) Dual specificity mitogen-activated protein kinase kinase 2| (EC 2.7.12.2) (MAP kinase kinase 2) (MAPKK 2) (ERK activator kinase 2) (MAPK/ERK kinase 2) (MEK2) Length = 398 Score = 37.4 bits (85), Expect = 0.028 Identities = 22/63 (34%), Positives = 32/63 (50%), Gaps = 5/63 (7%) Frame = -1 Query: 545 SVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKH-----ARKYID 381 S VG+ YM+PE L S +SDI+S+GL ++E+S D K R +D Sbjct: 224 SFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVELSIGRYPIPPPDSKELEAIFGRPVVD 283 Query: 380 GVK 372 G + Sbjct: 284 GAE 286
>E2AK1_RAT (Q63185) Eukaryotic translation initiation factor 2-alpha kinase 1| (EC 2.7.11.1) (Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase) (Heme-regulated inhibitor) (Heme-controlled repressor) (HCR) (Hemin-sensitive initiation factor 2- Length = 620 Score = 37.4 bits (85), Expect = 0.028 Identities = 17/35 (48%), Positives = 25/35 (71%) Frame = -1 Query: 545 SVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEI 441 S VG+ Y +PE L E A+SD+YSLG+I++E+ Sbjct: 487 SRVGTCLYASPEQLEGSEYDAKSDMYSLGVILLEL 521
>PKNB_LACLA (Q9CEF5) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 627 Score = 37.4 bits (85), Expect = 0.028 Identities = 15/39 (38%), Positives = 26/39 (66%) Frame = -1 Query: 551 TRSVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEIST 435 T ++ GSV Y++PE + +SDIY++G+I+ E+ T Sbjct: 169 TNTMFGSVHYLSPEQARGSNATVQSDIYAIGIILFELLT 207
>CSF1R_FELCA (P13369) Macrophage colony-stimulating factor 1 receptor precursor| (CSF-1-R) (EC 2.7.10.1) (Fms proto-oncogene) (c-fms) Length = 980 Score = 37.4 bits (85), Expect = 0.028 Identities = 24/106 (22%), Positives = 53/106 (50%) Frame = -1 Query: 530 VGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKENWTLEK 351 V +MAPE +++ + +SD++S G+++ EI + +N G+ N K Sbjct: 817 VKWMAPESIFDCVYTVQSDVWSYGILLWEIFSLGLNP-----------YPGILVNSKFYK 865 Query: 350 IMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNK 213 ++ + ++ + AF + +I C ++ +RP+ + I ++L K Sbjct: 866 LVKDGYQMAQPAF-APKNIYSIMQACWALEPTRRPTFQQICSLLQK 910
>KIT_HUMAN (P10721) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen) Length = 976 Score = 37.0 bits (84), Expect = 0.037 Identities = 30/115 (26%), Positives = 55/115 (47%) Frame = -1 Query: 530 VGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKENWTLEK 351 V +MAPE ++N + SD++S G+ + E+ + +S K+ +KE + + Sbjct: 833 VKWMAPESIFNCVYTFESDVWSYGIFLWELFSLG-SSPYPGMPVDSKFYKMIKEGFRMLS 891 Query: 350 IMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNKLPVSEEVSH 186 EHA ++ +I C + D KRP+ + IV ++ K +SE +H Sbjct: 892 --------PEHAPAEM---YDIMKTCWDADPLKRPTFKQIVQLIEK-QISESTNH 934
>PKN5_MYXXA (P54737) Serine/threonine-protein kinase pkn5 (EC 2.7.11.1)| Length = 380 Score = 37.0 bits (84), Expect = 0.037 Identities = 15/34 (44%), Positives = 24/34 (70%) Frame = -1 Query: 542 VVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEI 441 +VG+ YMAPE + + R+D+YSLG+I+ E+ Sbjct: 281 LVGTYRYMAPEQILGEPLDGRADLYSLGVILYEL 314
>MP2K2_HUMAN (P36507) Dual specificity mitogen-activated protein kinase kinase 2| (EC 2.7.12.2) (MAP kinase kinase 2) (MAPKK 2) (ERK activator kinase 2) (MAPK/ERK kinase 2) (MEK2) Length = 400 Score = 37.0 bits (84), Expect = 0.037 Identities = 22/61 (36%), Positives = 31/61 (50%), Gaps = 5/61 (8%) Frame = -1 Query: 545 SVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKH-----ARKYID 381 S VG+ YMAPE L S +SDI+S+GL ++E++ D K R +D Sbjct: 226 SFVGTRSYMAPERLQGTHYSVQSDIWSMGLSLVELAVGRYPIPPPDAKELEAIFGRPVVD 285 Query: 380 G 378 G Sbjct: 286 G 286
>KIT_CAPHI (Q28317) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 978 Score = 37.0 bits (84), Expect = 0.037 Identities = 30/115 (26%), Positives = 55/115 (47%) Frame = -1 Query: 530 VGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKENWTLEK 351 V +MAPE ++N + SD++S G+ + E+ + +S K+ +KE + + Sbjct: 835 VKWMAPESIFNCVYTFESDVWSYGIFLWELFSLG-SSPYPGMPVDSKFYKMIKEGFRMLS 893 Query: 350 IMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNKLPVSEEVSH 186 EHA ++ +I C + D KRP+ + IV ++ K +SE +H Sbjct: 894 --------PEHAPAEM---YDIMKTCWDADPLKRPTFKQIVQLIEK-QISESTNH 936
>NEK7_HUMAN (Q8TDX7) Serine/threonine-protein kinase Nek7 (EC 2.7.11.1)| (NimA-related protein kinase 7) Length = 302 Score = 37.0 bits (84), Expect = 0.037 Identities = 27/114 (23%), Positives = 57/114 (50%), Gaps = 2/114 (1%) Frame = -1 Query: 545 SVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKEN 366 S+VG+ YM+PE ++ + +SDI+SLG ++ E++ + Y D + Sbjct: 195 SLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAA----------LQSPFYGDKMNLY 244 Query: 365 WTLEKI-MSEYIEL-EEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNKL 210 +KI +Y L +H +++ +N+ C+ D +KRP + + ++ ++ Sbjct: 245 SLCKKIEQCDYPPLPSDHYSEELRQLVNM---CINPDPEKRPDVTYVYDVAKRM 295
>PKNA2_BIFLO (Q8G4G1) Probable serine/threonine-protein kinase pknA2 (EC| 2.7.11.1) Length = 757 Score = 37.0 bits (84), Expect = 0.037 Identities = 14/39 (35%), Positives = 27/39 (69%) Frame = -1 Query: 551 TRSVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEIST 435 T ++G+ Y+APE + N + +A+ D+YS+G++ E+ T Sbjct: 173 TGMLLGTAAYLAPEMIENNQATAQGDLYSVGIMAWEMLT 211
>INSR_MOUSE (P15208) Insulin receptor precursor (EC 2.7.10.1) (IR) [Contains:| Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1372 Score = 37.0 bits (84), Expect = 0.037 Identities = 32/132 (24%), Positives = 61/132 (46%), Gaps = 19/132 (14%) Frame = -1 Query: 530 VGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKENWTLEK 351 V +M+PE L +G +A SD++S G+++ EI++ A + G+ L+ Sbjct: 1190 VRWMSPESLKDGVFTASSDMWSFGVVLWEITSL-----------AEQPYQGLSNEQVLKF 1238 Query: 350 IMSE-YIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNML--------------- 219 +M Y++ ++ +++ + + C + + K RP+ IVN+L Sbjct: 1239 VMDGGYLDPPDNCPERLTDLMRM---CWQFNPKMRPTFLEIVNLLKDDLHPSFPEVSFFY 1295 Query: 218 ---NKLPVSEEV 192 NK P SEE+ Sbjct: 1296 SEENKAPESEEL 1307
>E2AK1_HUMAN (Q9BQI3) Eukaryotic translation initiation factor 2-alpha kinase 1| (EC 2.7.11.1) (Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase) (Heme-regulated inhibitor) (Heme-controlled repressor) (HCR) (Hemin-sensitive initiation factor Length = 630 Score = 37.0 bits (84), Expect = 0.037 Identities = 16/35 (45%), Positives = 25/35 (71%) Frame = -1 Query: 545 SVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEI 441 S VG+ Y +PE L E A+SD+YSLG++++E+ Sbjct: 489 SRVGTCLYASPEQLEGSEYDAKSDMYSLGVVLLEL 523
>INSR_RAT (P15127) Insulin receptor precursor (EC 2.7.10.1) (IR) [Contains:| Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1383 Score = 37.0 bits (84), Expect = 0.037 Identities = 32/132 (24%), Positives = 61/132 (46%), Gaps = 19/132 (14%) Frame = -1 Query: 530 VGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKENWTLEK 351 V +M+PE L +G +A SD++S G+++ EI++ A + G+ L+ Sbjct: 1201 VRWMSPESLKDGVFTASSDMWSFGVVLWEITSL-----------AEQPYQGLSNEQVLKF 1249 Query: 350 IMSE-YIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNML--------------- 219 +M Y++ ++ +++ + + C + + K RP+ IVN+L Sbjct: 1250 VMDGGYLDPPDNCPERLTDLMRM---CWQFNPKMRPTFLEIVNLLKDDLHPSFPEVSFFY 1306 Query: 218 ---NKLPVSEEV 192 NK P SEE+ Sbjct: 1307 SEENKAPESEEL 1318
>KIT_BOVIN (P43481) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 977 Score = 37.0 bits (84), Expect = 0.037 Identities = 30/115 (26%), Positives = 55/115 (47%) Frame = -1 Query: 530 VGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKENWTLEK 351 V +MAPE ++N + SD++S G+ + E+ + +S K+ +KE + + Sbjct: 834 VKWMAPESIFNCVYTFESDVWSYGIFLWELFSLG-SSPYPGMPVDSKFYKMIKEGFRMLS 892 Query: 350 IMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNKLPVSEEVSH 186 EHA ++ +I C + D KRP+ + IV ++ K +SE +H Sbjct: 893 --------PEHAPAEM---YDIMKTCWDADPLKRPTFKQIVQLIEK-QISESTNH 935
>EPHA5_MOUSE (Q60629) Ephrin type-A receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Brain-specific kinase) (CEK-7) Length = 877 Score = 36.6 bits (83), Expect = 0.049 Identities = 29/109 (26%), Positives = 50/109 (45%), Gaps = 2/109 (1%) Frame = -1 Query: 530 VGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNS--SSTDQKHARKYIDGVKENWTL 357 + + APE + + ++ SD++S G+++ E+ + T+Q I V+E + L Sbjct: 681 IRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQD----VIKAVEEGYRL 736 Query: 356 EKIMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNKL 210 M D A + L C + D+ RP + IVNML+KL Sbjct: 737 PSPM-----------DCPAALYQLMLDCWQKDRNSRPKFDEIVNMLDKL 774
>EPHA3_MOUSE (P29319) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ETK1) (MEK4) Length = 983 Score = 36.6 bits (83), Expect = 0.049 Identities = 27/107 (25%), Positives = 49/107 (45%) Frame = -1 Query: 530 VGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKENWTLEK 351 + + +PE + + ++ SD++S G+++ E+ + S Q + I V E + L Sbjct: 788 IRWTSPEAMSYRKFTSASDVWSYGIVLWEVMSYGERPYS--QMSNQDVIKAVDERYRLPP 845 Query: 350 IMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNKL 210 M D A + L C + D+ RP E IV++L+KL Sbjct: 846 PM-----------DCPAALYQLMLDCWQKDRNNRPKFEQIVSILDKL 881
>EPHA5_RAT (P54757) Ephrin type-A receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) Length = 1005 Score = 36.6 bits (83), Expect = 0.049 Identities = 29/109 (26%), Positives = 50/109 (45%), Gaps = 2/109 (1%) Frame = -1 Query: 530 VGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNS--SSTDQKHARKYIDGVKENWTL 357 + + APE + + ++ SD++S G+++ E+ + T+Q I V+E + L Sbjct: 844 IRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQD----VIKAVEEGYRL 899 Query: 356 EKIMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNKL 210 M D A + L C + D+ RP + IVNML+KL Sbjct: 900 PSPM-----------DCPAALYQLMLDCWQKDRNSRPKFDDIVNMLDKL 937
>PKN2_CORGL (Q8NU97) Serine/threonine protein kinases pknA (EC 2.7.11.1)| Length = 469 Score = 36.6 bits (83), Expect = 0.049 Identities = 17/37 (45%), Positives = 25/37 (67%) Frame = -1 Query: 551 TRSVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEI 441 T VVG+ Y++PE E++A SDIYSLG++ E+ Sbjct: 181 TGMVVGTAQYVSPEQAQGKEVTAASDIYSLGVVGYEM 217
>M3K12_HUMAN (Q12852) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 859 Score = 36.2 bits (82), Expect = 0.063 Identities = 15/37 (40%), Positives = 25/37 (67%) Frame = -1 Query: 545 SVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEIST 435 S G+V +MAPE + N +S + DI+S G+++ E+ T Sbjct: 269 SFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLT 305
>NEK9_MOUSE (Q8K1R7) Serine/threonine-protein kinase Nek9 (EC 2.7.11.1)| (NimA-related protein kinase 9) (Never in mitosis A-related kinase 9) Length = 984 Score = 36.2 bits (82), Expect = 0.063 Identities = 26/110 (23%), Positives = 58/110 (52%), Gaps = 2/110 (1%) Frame = -1 Query: 545 SVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKH-ARKYIDGVKE 369 ++VG+ YM+PE + + +SDI+++G +I E+ T +T+ + K + G++ Sbjct: 210 TLVGTPYYMSPELCQGVKYNFKSDIWAVGCVIFELLTLKRTFDATNPLNLCVKIVQGIR- 268 Query: 368 NWTLEKIMSEY-IELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNM 222 +E S+Y +EL I + C++ D ++RP+ + ++++ Sbjct: 269 --AMEVDSSQYSLEL-----------IQLVHACLDQDPEQRPAADALLDL 305
>M3K13_HUMAN (O43283) Mitogen-activated protein kinase kinase kinase 13 (EC| 2.7.11.25) (Mixed lineage kinase) (MLK) (Leucine zipper-bearing kinase) Length = 966 Score = 36.2 bits (82), Expect = 0.063 Identities = 15/37 (40%), Positives = 25/37 (67%) Frame = -1 Query: 545 SVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEIST 435 S G+V +MAPE + N +S + DI+S G+++ E+ T Sbjct: 312 SFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLT 348
>M3K12_RAT (Q63796) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 888 Score = 36.2 bits (82), Expect = 0.063 Identities = 15/37 (40%), Positives = 25/37 (67%) Frame = -1 Query: 545 SVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEIST 435 S G+V +MAPE + N +S + DI+S G+++ E+ T Sbjct: 302 SFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLT 338
>M3K12_MOUSE (Q60700) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 888 Score = 36.2 bits (82), Expect = 0.063 Identities = 15/37 (40%), Positives = 25/37 (67%) Frame = -1 Query: 545 SVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEIST 435 S G+V +MAPE + N +S + DI+S G+++ E+ T Sbjct: 302 SFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLT 338
>KYK1_DICDI (P18160) Non-receptor tyrosine kinase spore lysis A (EC 2.7.10.2)| (Tyrosine-protein kinase 1) Length = 1584 Score = 36.2 bits (82), Expect = 0.063 Identities = 15/35 (42%), Positives = 22/35 (62%) Frame = -1 Query: 539 VGSVGYMAPEYLYNGEISARSDIYSLGLIIMEIST 435 VG + YMAPE S +SD+YS G+++ E+ T Sbjct: 1466 VGCIPYMAPEVFKGDSNSEKSDVYSYGMVLFELLT 1500
>PKN1_THETN (Q8R9T6) Probable serine/threonine-protein kinase Sps1 (EC| 2.7.11.1) Length = 625 Score = 36.2 bits (82), Expect = 0.063 Identities = 15/39 (38%), Positives = 24/39 (61%) Frame = -1 Query: 551 TRSVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEIST 435 T V+G+ Y +PE + R+DIYSLG+++ E+ T Sbjct: 167 TGDVIGTAYYFSPEQAKGSIVDERTDIYSLGIVLFEMLT 205
>E2AK1_RABIT (P33279) Eukaryotic translation initiation factor 2-alpha kinase 1| (EC 2.7.11.1) (Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase) (Heme-regulated inhibitor) (Heme-controlled repressor) (HCR) (Hemin-sensitive initiation factor Length = 626 Score = 36.2 bits (82), Expect = 0.063 Identities = 16/35 (45%), Positives = 25/35 (71%) Frame = -1 Query: 545 SVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEI 441 S VG+ Y +PE L E A+SD+YS+G+I++E+ Sbjct: 484 SRVGTCLYASPEQLEGSEYDAKSDMYSVGVILLEL 518
>E2AK1_MOUSE (Q9Z2R9) Eukaryotic translation initiation factor 2-alpha kinase 1| (EC 2.7.11.1) (Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase) (Heme-regulated inhibitor) (Heme-controlled repressor) (HCR) (Hemin-sensitive initiation factor Length = 619 Score = 36.2 bits (82), Expect = 0.063 Identities = 16/35 (45%), Positives = 25/35 (71%) Frame = -1 Query: 545 SVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEI 441 S VG+ Y +PE L + A+SD+YSLG+I++E+ Sbjct: 486 SRVGTCLYASPEQLEGSQYDAKSDMYSLGVILLEL 520
>PKSC_STRCO (Q9S2C0) Serine/threonine protein kinase pksC (EC 2.7.11.1)| Length = 556 Score = 36.2 bits (82), Expect = 0.063 Identities = 15/39 (38%), Positives = 26/39 (66%) Frame = -1 Query: 551 TRSVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEIST 435 T VVG+ Y++PE + ARSD+YS+G+++ ++ T Sbjct: 186 TGMVVGTPQYLSPEQALGRGVDARSDLYSVGIMLFQLVT 224
>KIT_FELCA (Q28889) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 978 Score = 35.8 bits (81), Expect = 0.083 Identities = 29/115 (25%), Positives = 55/115 (47%) Frame = -1 Query: 530 VGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKENWTLEK 351 V +MAPE ++N + SD++S G+ + E+ + +S K+ +KE + + Sbjct: 834 VKWMAPESIFNCVYTFESDVWSYGIFLWELFSLG-SSPYPGMPVDSKFYKMIKEGFRMLS 892 Query: 350 IMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNKLPVSEEVSH 186 EHA ++ +I C + D KRP+ + IV ++ K +S+ +H Sbjct: 893 --------PEHAPAEM---YDIMKTCWDADPLKRPTFKQIVQLIEK-QISDSTNH 935
>HTK7_HYDAT (Q25197) Putative insulin-like peptide receptor precursor (EC| 2.7.10.1) Length = 1477 Score = 35.8 bits (81), Expect = 0.083 Identities = 29/105 (27%), Positives = 49/105 (46%), Gaps = 1/105 (0%) Frame = -1 Query: 530 VGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKENWTLEK 351 + +MAPE L +G S SD++S G+++ EI T A + G L Sbjct: 1216 IRWMAPESLKDGIFSTASDVWSFGVVLWEICTL-----------ASQPYQGKTNEQVLNF 1264 Query: 350 IMSE-YIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNML 219 ++S +++ E Q+ +++ C D K RPS IV++L Sbjct: 1265 VLSNGHLDYPEGCDYQLREFMSL---CWHRDPKMRPSFLEIVHVL 1306
>SKH1_SCHPO (Q9Y884) MAP kinase kinase skh1/pek1 (EC 2.7.12.2)| Length = 363 Score = 35.8 bits (81), Expect = 0.083 Identities = 16/33 (48%), Positives = 23/33 (69%) Frame = -1 Query: 536 GSVGYMAPEYLYNGEISARSDIYSLGLIIMEIS 438 G+ YMAPE + G + SDI+SLGL +ME++ Sbjct: 241 GTSYYMAPERISGGSYTISSDIWSLGLTLMEVA 273
>NEK1_HUMAN (Q96PY6) Serine/threonine-protein kinase Nek1 (EC 2.7.11.1)| (NimA-related protein kinase 1) (NY-REN-55 antigen) Length = 1258 Score = 35.8 bits (81), Expect = 0.083 Identities = 26/107 (24%), Positives = 53/107 (49%) Frame = -1 Query: 548 RSVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKE 369 R+ +G+ Y++PE N + +SDI++LG ++ E+ T KHA + G + Sbjct: 161 RTCIGTPYYLSPEICENKPYNNKSDIWALGCVLYELCT---------LKHA--FEAGSMK 209 Query: 368 NWTLEKIMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIV 228 N L+ I + + H + + ++ Q + + + RPS+ +I+ Sbjct: 210 NLVLKIISGSFPPVSLHYSYDLRSLVS---QLFKRNPRDRPSVNSIL 253
>GRK5_RAT (Q62833) G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK5) Length = 590 Score = 35.8 bits (81), Expect = 0.083 Identities = 20/56 (35%), Positives = 27/56 (48%) Frame = -1 Query: 548 RSVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYID 381 R VG+VGYMAPE L N D + LG +I E+ +K R+ +D Sbjct: 343 RGRVGTVGYMAPEVLNNQRYGLSPDYWGLGCLIYEMIEGQSPFRGRKEKVKREEVD 398
>GRK5_MOUSE (Q8VEB1) G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK5) Length = 590 Score = 35.8 bits (81), Expect = 0.083 Identities = 20/56 (35%), Positives = 27/56 (48%) Frame = -1 Query: 548 RSVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYID 381 R VG+VGYMAPE L N D + LG +I E+ +K R+ +D Sbjct: 343 RGRVGTVGYMAPEVLNNQRYGLSPDYWGLGCLIYEMIEGQSPFRGRKEKVKREEVD 398
>GRK5_HUMAN (P34947) G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK5) Length = 590 Score = 35.8 bits (81), Expect = 0.083 Identities = 20/56 (35%), Positives = 27/56 (48%) Frame = -1 Query: 548 RSVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYID 381 R VG+VGYMAPE L N D + LG +I E+ +K R+ +D Sbjct: 343 RGRVGTVGYMAPEVLNNQRYGLSPDYWGLGCLIYEMIEGQSPFRGRKEKVKREEVD 398
>GRK5_BOVIN (P43249) G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK5) Length = 590 Score = 35.8 bits (81), Expect = 0.083 Identities = 20/56 (35%), Positives = 27/56 (48%) Frame = -1 Query: 548 RSVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYID 381 R VG+VGYMAPE L N D + LG +I E+ +K R+ +D Sbjct: 343 RGRVGTVGYMAPEVLNNQRYGLSPDYWGLGCLIYEMIEGQSPFRGRKEKVKREEVD 398
>KIT_CANFA (O97799) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 975 Score = 35.8 bits (81), Expect = 0.083 Identities = 29/115 (25%), Positives = 55/115 (47%) Frame = -1 Query: 530 VGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKENWTLEK 351 V +MAPE ++N + SD++S G+ + E+ + +S K+ +KE + + Sbjct: 832 VKWMAPESIFNCVYTFESDVWSYGIFLWELFSLG-SSPYPGMPVDSKFYKMIKEGFRMLS 890 Query: 350 IMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNKLPVSEEVSH 186 EHA ++ +I C + D KRP+ + IV ++ K +S+ +H Sbjct: 891 --------PEHAPAEM---YDIMKTCWDADPLKRPTFKQIVQLIEK-QISDSTNH 933
>CCAMK_PEA (Q6RET6) Calcium and calcium/calmodulin-dependent| serine/threonine-protein kinase (EC 2.7.11.17) (PsCCaMK) (Ps-SYM9) (Fragment) Length = 527 Score = 35.8 bits (81), Expect = 0.083 Identities = 14/29 (48%), Positives = 24/29 (82%) Frame = -1 Query: 536 GSVGYMAPEYLYNGEISARSDIYSLGLII 450 GS+ Y++PE L G+I+ +SD++SLG+I+ Sbjct: 218 GSIDYVSPEALSQGKITTKSDMWSLGVIL 246
>DSOR1_DROME (Q24324) Dual specificity mitogen-activated protein kinase kinase| dSOR1 (EC 2.7.12.2) (Downstream of RAF) (MAPKK) Length = 396 Score = 35.8 bits (81), Expect = 0.083 Identities = 17/36 (47%), Positives = 25/36 (69%) Frame = -1 Query: 545 SVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEIS 438 S VG+ YM+PE L S +SDI+SLGL ++E++ Sbjct: 241 SFVGTRSYMSPERLQGTHYSVQSDIWSLGLSLVEMA 276
>GUC2C_RAT (P23897) Heat-stable enterotoxin receptor precursor (GC-C)| (Intestinal guanylate cyclase) (EC 4.6.1.2) (STA receptor) Length = 1072 Score = 35.8 bits (81), Expect = 0.083 Identities = 27/105 (25%), Positives = 49/105 (46%) Frame = -1 Query: 524 YMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKENWTLEKIM 345 + APE+L IS + D+YS +I EI R + + + I V+ ++ + Sbjct: 645 WTAPEHLRQATISQKGDVYSFSIIAQEIILRKETFYTLSCRDQNEKIFRVENSYGTKPFR 704 Query: 344 SEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNKL 210 + + LE ++E + + C E D +KRP + I + L K+ Sbjct: 705 PD-LFLETADEKELEVYLLV-KSCWEEDPEKRPDFKKIESTLAKI 747
>PKN2_CLOPE (Q8XJL8) Probable serine/threonine protein kinase CPE1738 (EC| 2.7.11.1) Length = 685 Score = 35.8 bits (81), Expect = 0.083 Identities = 16/39 (41%), Positives = 24/39 (61%) Frame = -1 Query: 551 TRSVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEIST 435 T SV+GS Y +PE R+D+YSLG+++ E+ T Sbjct: 166 TNSVMGSAHYFSPEQAKGTYTDYRTDLYSLGIVLYEMVT 204
>NEK1_MOUSE (P51954) Serine/threonine-protein kinase Nek1 (EC 2.7.11.1)| (NimA-related protein kinase 1) Length = 1203 Score = 35.8 bits (81), Expect = 0.083 Identities = 26/107 (24%), Positives = 53/107 (49%) Frame = -1 Query: 548 RSVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKE 369 R+ +G+ Y++PE N + +SDI++LG ++ E+ T KHA + G + Sbjct: 161 RTCIGTPYYLSPEICENKPYNNKSDIWALGCVLYELCT---------LKHA--FEAGNMK 209 Query: 368 NWTLEKIMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIV 228 N L+ I + + H + + ++ Q + + + RPS+ +I+ Sbjct: 210 NLVLKIISGSFPPVSPHYSYDLRSLLS---QLFKRNPRDRPSVNSIL 253
>CCAMK_MEDTR (Q6RET7) Calcium and calcium/calmodulin-dependent| serine/threonine-protein kinase DMI-3 (EC 2.7.11.17) (Does not make infections protein 3) (CCaMK DMI3) (MtCCaMK) Length = 523 Score = 35.8 bits (81), Expect = 0.083 Identities = 14/29 (48%), Positives = 24/29 (82%) Frame = -1 Query: 536 GSVGYMAPEYLYNGEISARSDIYSLGLII 450 GS+ Y++PE L G+I+ +SD++SLG+I+ Sbjct: 210 GSIDYVSPEALSQGKITTKSDMWSLGVIL 238
>MP2K2_RAT (P36506) Dual specificity mitogen-activated protein kinase kinase 2| (EC 2.7.12.2) (MAP kinase kinase 2) (MAPKK 2) (ERK activator kinase 2) (MAPK/ERK kinase 2) (MEK2) Length = 400 Score = 35.4 bits (80), Expect = 0.11 Identities = 16/36 (44%), Positives = 25/36 (69%) Frame = -1 Query: 545 SVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEIS 438 S VG+ YM+PE L S +SDI+S+GL ++E++ Sbjct: 226 SFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVELA 261
>IGF1R_XENLA (O73798) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (xIGF-1R) (xIGFR) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] Length = 1358 Score = 35.4 bits (80), Expect = 0.11 Identities = 43/175 (24%), Positives = 77/175 (44%), Gaps = 3/175 (1%) Frame = -1 Query: 530 VGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKENWTLEK 351 V +M+PE L +G + SD++S G+++ EI+T A + G+ L Sbjct: 1172 VRWMSPESLKDGVFTTNSDVWSFGVVLWEIATL-----------AEQPYQGMSNEQVLRF 1220 Query: 350 IM-SEYIELEEHAFDQVEACINIGLQCVEIDQKKRPS-IETIVNMLNKL-PVSEEVSHSM 180 +M +E ++ D + + C + + K RPS +E I ++ ++L P +EVS Sbjct: 1221 VMEGGLLEKPDNCPDML---FELMRMCWQFNPKMRPSFLEIISSIKDELDPGFKEVSFFY 1277 Query: 179 *AQNFPLFSERCPT*SKHKINAMKVDDETTICCIQXSNP*WHFINKKSINEKCIV 15 +N P +E + ++ +D C +Q S H KS N +V Sbjct: 1278 SEENKPPDTEELDL-EAENMESIPLDPS---CALQNSE---HHAGHKSENGPGVV 1325
>PKNH_MYCBO (Q7U095) Probable serine/threonine-protein kinase pknH (EC| 2.7.11.1) Length = 596 Score = 35.4 bits (80), Expect = 0.11 Identities = 16/37 (43%), Positives = 24/37 (64%) Frame = -1 Query: 545 SVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEIST 435 + VG+ YMAPE N E++ R+DIY+L ++ E T Sbjct: 174 TAVGTWKYMAPERFSNDEVTYRADIYALACVLHECLT 210
>PKNH_MYCTU (Q11053) Probable serine/threonine-protein kinase pknH (EC| 2.7.11.1) Length = 626 Score = 35.4 bits (80), Expect = 0.11 Identities = 16/37 (43%), Positives = 24/37 (64%) Frame = -1 Query: 545 SVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEIST 435 + VG+ YMAPE N E++ R+DIY+L ++ E T Sbjct: 174 TAVGTWKYMAPERFSNDEVTYRADIYALACVLHECLT 210
>PKND_MYCTU (O05871) Serine/threonine-protein kinase pknD (EC 2.7.11.1)| Length = 664 Score = 35.4 bits (80), Expect = 0.11 Identities = 16/39 (41%), Positives = 24/39 (61%) Frame = -1 Query: 551 TRSVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEIST 435 T + VG+ YMAPE E++ R+DIY+L ++ E T Sbjct: 171 TGTAVGTYNYMAPERFTGDEVTYRADIYALACVLGECLT 209
>YSK4_HUMAN (Q56UN5) SPS1/STE20-related protein kinase YSK4 (EC 2.7.11.1)| (Regulated in COPD, protein kinase) Length = 1328 Score = 35.4 bits (80), Expect = 0.11 Identities = 29/102 (28%), Positives = 49/102 (48%) Frame = -1 Query: 548 RSVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKE 369 +S+ G+ +MAPE + +SDI+S+G + E++T +S D+ A YI + Sbjct: 1225 KSMHGTPYWMAPEVINESGYGRKSDIWSIGCTVFEMATGKPPLASMDRMAAMFYIGAHR- 1283 Query: 368 NWTLEKIMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPS 243 L + ++ E+A D V C+ DQ +RPS Sbjct: 1284 --GLMPPLPDH--FSENAADFVRMCLT-------RDQHERPS 1314
>MKH1_SCHPO (Q10407) MAP kinase kinase kinase mkh1 (EC 2.7.11.25)| Length = 1116 Score = 35.4 bits (80), Expect = 0.11 Identities = 29/110 (26%), Positives = 53/110 (48%), Gaps = 3/110 (2%) Frame = -1 Query: 545 SVVGSVGYMAPEYLYNGE--ISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVK 372 S+ GS+ +MAPE ++N SA+ D++SLG +++E+ STD+ + G + Sbjct: 991 SMQGSIFWMAPEVIHNDHQGYSAKVDVWSLGCVVLEM-LAGRRPWSTDEAIQAMFKLGTE 1049 Query: 371 ENWTLEKIMSEYI-ELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVN 225 + I SE + ++ A + AC + RP+ E ++N Sbjct: 1050 KK--APPIPSELVSQVSPEAIQFLNACFTVNADV-------RPTAEELLN 1090
>STK35_HUMAN (Q8TDR2) Serine/threonine-protein kinase 35 (EC 2.7.11.1)| (CLP-36-interacting kinase) (Clik1) (PDLIM1-interacting kinase 1) Length = 401 Score = 35.4 bits (80), Expect = 0.11 Identities = 31/111 (27%), Positives = 52/111 (46%) Frame = -1 Query: 545 SVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKEN 366 S GS YMAPE ++ G +A++DI++LG+II + R +ID + Sbjct: 281 SACGSDFYMAPE-VWEGHYTAKADIFALGIIIWAMIERI------------TFID----S 323 Query: 365 WTLEKIMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNK 213 T ++++ YI+ EA + + I QK+R S+ + L K Sbjct: 324 ETKKELLGTYIKQGTEIVPVGEALLENPKMELHIPQKRRTSMSEGIKQLLK 374
>MP2K2_MOUSE (Q63932) Dual specificity mitogen-activated protein kinase kinase 2| (EC 2.7.12.2) (MAP kinase kinase 2) (MAPKK 2) (ERK activator kinase 2) (MAPK/ERK kinase 2) (MEK2) Length = 401 Score = 35.4 bits (80), Expect = 0.11 Identities = 16/36 (44%), Positives = 25/36 (69%) Frame = -1 Query: 545 SVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEIS 438 S VG+ YM+PE L S +SDI+S+GL ++E++ Sbjct: 226 SFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVELA 261
>MP2K1_XENLA (Q05116) Dual specificity mitogen-activated protein kinase kinase 1| (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) Length = 394 Score = 35.0 bits (79), Expect = 0.14 Identities = 16/36 (44%), Positives = 25/36 (69%) Frame = -1 Query: 545 SVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEIS 438 S VG+ YM+PE L S +SDI+S+GL ++E++ Sbjct: 221 SFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMA 256
>MP2K1_SERCA (Q91447) Dual specificity mitogen-activated protein kinase kinase 1| (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) (Fragment) Length = 388 Score = 35.0 bits (79), Expect = 0.14 Identities = 16/36 (44%), Positives = 25/36 (69%) Frame = -1 Query: 545 SVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEIS 438 S VG+ YM+PE L S +SDI+S+GL ++E++ Sbjct: 215 SFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMA 250
>KCCS_MALDO (Q07250) Calcium/calmodulin-dependent serine/threonine-protein| kinase (EC 2.7.11.17) Length = 415 Score = 35.0 bits (79), Expect = 0.14 Identities = 12/29 (41%), Positives = 25/29 (86%) Frame = -1 Query: 536 GSVGYMAPEYLYNGEISARSDIYSLGLII 450 GS+ Y++PE L G+++++SD+++LG+I+ Sbjct: 212 GSIDYVSPEALSQGQVTSKSDMWALGVIL 240
>PKN1_CORGL (Q8NU98) Probable serine/threonine protein kinase pknB (EC| 2.7.11.1) Length = 646 Score = 35.0 bits (79), Expect = 0.14 Identities = 15/39 (38%), Positives = 24/39 (61%) Frame = -1 Query: 551 TRSVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEIST 435 T +V+G+ Y++PE ARSDIY+ G ++ E+ T Sbjct: 171 TSAVIGTAQYLSPEQARGKPADARSDIYATGCVMYELVT 209
>M3K13_PONPY (Q5R8X7) Mitogen-activated protein kinase kinase kinase 13 (EC| 2.7.11.25) Length = 966 Score = 35.0 bits (79), Expect = 0.14 Identities = 14/37 (37%), Positives = 25/37 (67%) Frame = -1 Query: 545 SVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEIST 435 S G+V ++APE + N +S + DI+S G+++ E+ T Sbjct: 312 SFAGTVAWLAPEVIRNEPVSEKVDIWSFGVVLWELLT 348
>FRK_HUMAN (P42685) Tyrosine-protein kinase FRK (EC 2.7.10.2) (Nuclear| tyrosine protein kinase RAK) Length = 505 Score = 35.0 bits (79), Expect = 0.14 Identities = 25/104 (24%), Positives = 46/104 (44%), Gaps = 4/104 (3%) Frame = -1 Query: 530 VGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKENWTLEK 351 V + APE + + + S +SD++S G+++ EI T + + G+ ++ Sbjct: 397 VKWTAPEAIRSNKFSIKSDVWSFGILLYEIIT-----------YGKMPYSGMTGAQVIQM 445 Query: 350 IMSEYIELEEHAFDQVEAC----INIGLQCVEIDQKKRPSIETI 231 + Y Q C NI L+C + K+RP+ ET+ Sbjct: 446 LAQNY------RLPQPSNCPQQFYNIMLECWNAEPKERPTFETL 483
>AVR2A_SHEEP (Q28560) Activin receptor type 2A precursor (EC 2.7.11.30) (Activin| receptor type IIA) (ACTR-IIA) Length = 513 Score = 35.0 bits (79), Expect = 0.14 Identities = 21/105 (20%), Positives = 51/105 (48%), Gaps = 7/105 (6%) Frame = -1 Query: 551 TRSVVGSVGYMAPEYL-----YNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKY 387 T VG+ YMAPE L + + R D+Y++GL++ E+++R + ++ + Sbjct: 356 THGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELASRCTAADGPVDEYMLPF 415 Query: 386 IDGVKENWTLEKIMSEYIELEEHAF--DQVEACINIGLQCVEIDQ 258 ++ + ++ +LE + + ++ D + + + C I++ Sbjct: 416 VEEIGQHPSLEDMQEVVVHKKKRPVLRDYWQKLAGMAMLCETIEE 460
>EPHA5_HUMAN (P54756) Ephrin type-A receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Receptor protein-tyrosine kinase HEK7) Length = 1037 Score = 35.0 bits (79), Expect = 0.14 Identities = 28/109 (25%), Positives = 50/109 (45%), Gaps = 2/109 (1%) Frame = -1 Query: 530 VGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNS--SSTDQKHARKYIDGVKENWTL 357 + + APE + + ++ SD++S G+++ E+ + T+Q I V+E + L Sbjct: 842 IRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQD----VIKAVEEGYRL 897 Query: 356 EKIMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNKL 210 M D A + L C + ++ RP + IVNML+KL Sbjct: 898 PSPM-----------DCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKL 935
>MP2K1_CRIGR (Q63980) Dual specificity mitogen-activated protein kinase kinase 1| (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) Length = 393 Score = 35.0 bits (79), Expect = 0.14 Identities = 16/36 (44%), Positives = 25/36 (69%) Frame = -1 Query: 545 SVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEIS 438 S VG+ YM+PE L S +SDI+S+GL ++E++ Sbjct: 222 SFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMA 257
>CDC15_YEAST (P27636) Cell division control protein 15 (EC 2.7.11.1)| Length = 974 Score = 35.0 bits (79), Expect = 0.14 Identities = 16/38 (42%), Positives = 26/38 (68%) Frame = -1 Query: 545 SVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEISTR 432 ++ G++ +MAPE L N S SDI+SLG ++E+ T+ Sbjct: 177 TLAGTLNWMAPEILGNRGASTLSDIWSLGATVVEMLTK 214
>MP2K1_RAT (Q01986) Dual specificity mitogen-activated protein kinase kinase 1| (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) Length = 392 Score = 35.0 bits (79), Expect = 0.14 Identities = 16/36 (44%), Positives = 25/36 (69%) Frame = -1 Query: 545 SVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEIS 438 S VG+ YM+PE L S +SDI+S+GL ++E++ Sbjct: 221 SFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMA 256
>MP2K1_RABIT (P29678) Dual specificity mitogen-activated protein kinase kinase 1| (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) Length = 392 Score = 35.0 bits (79), Expect = 0.14 Identities = 16/36 (44%), Positives = 25/36 (69%) Frame = -1 Query: 545 SVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEIS 438 S VG+ YM+PE L S +SDI+S+GL ++E++ Sbjct: 221 SFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMA 256
>MP2K1_MOUSE (P31938) Dual specificity mitogen-activated protein kinase kinase 1| (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) Length = 392 Score = 35.0 bits (79), Expect = 0.14 Identities = 16/36 (44%), Positives = 25/36 (69%) Frame = -1 Query: 545 SVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEIS 438 S VG+ YM+PE L S +SDI+S+GL ++E++ Sbjct: 221 SFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMA 256
>MP2K1_HUMAN (Q02750) Dual specificity mitogen-activated protein kinase kinase 1| (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) Length = 392 Score = 35.0 bits (79), Expect = 0.14 Identities = 16/36 (44%), Positives = 25/36 (69%) Frame = -1 Query: 545 SVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEIS 438 S VG+ YM+PE L S +SDI+S+GL ++E++ Sbjct: 221 SFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMA 256
>EPHA5_CHICK (P54755) Ephrin type-A receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor CEK7) Length = 1013 Score = 35.0 bits (79), Expect = 0.14 Identities = 28/109 (25%), Positives = 50/109 (45%), Gaps = 2/109 (1%) Frame = -1 Query: 530 VGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNS--SSTDQKHARKYIDGVKENWTL 357 + + APE + + ++ SD++S G+++ E+ + T+Q I V+E + L Sbjct: 818 IRWTAPEAIAFRKFTSASDVWSYGIVMWEVMSYGERPYWEMTNQD----VIKAVEEGYRL 873 Query: 356 EKIMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNKL 210 M D A + L C + D+ RP + IV+ML+KL Sbjct: 874 PSPM-----------DCPAALYQLMLDCWQKDRNSRPKFDEIVSMLDKL 911
>NEK9_HUMAN (Q8TD19) Serine/threonine-protein kinase Nek9 (EC 2.7.11.1)| (NimA-related protein kinase 9) (Never in mitosis A-related kinase 9) (Nercc1 kinase) (NIMA-related kinase 8) (Nek8) Length = 979 Score = 35.0 bits (79), Expect = 0.14 Identities = 26/109 (23%), Positives = 57/109 (52%), Gaps = 2/109 (1%) Frame = -1 Query: 545 SVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKH-ARKYIDGVKE 369 ++VG+ YM+PE + + +SDI+++G +I E+ T +T+ + K + G++ Sbjct: 210 TLVGTPYYMSPELCQGVKYNFKSDIWAVGCVIFELLTLKRTFDATNPLNLCVKIVQGIR- 268 Query: 368 NWTLEKIMSEY-IELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVN 225 +E S+Y +EL I + C++ D ++RP+ + +++ Sbjct: 269 --AMEVDSSQYSLEL-----------IQMVHSCLDQDPEQRPTADELLD 304
>KRAF1_DROME (P11346) Raf homolog serine/threonine-protein kinase dRAF-1 (EC| 2.7.11.1) (Protein pole-hole) Length = 739 Score = 35.0 bits (79), Expect = 0.14 Identities = 27/112 (24%), Positives = 49/112 (43%), Gaps = 3/112 (2%) Frame = -1 Query: 536 GSVGYMAPEYLYNGEI---SARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKEN 366 GS+ +MAPE + E+ S +SD+Y+ G+++ E+ + K ++ G Sbjct: 587 GSILWMAPEVIRMQELNPYSFQSDVYAFGIVMYELLAECLPYGHISNKDQILFMVG---R 643 Query: 365 WTLEKIMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNKL 210 L MS+ D +A + C++ K RP ++NML + Sbjct: 644 GLLRPDMSQVRS------DAPQALKRLAEDCIKYTPKDRPLFRPLLNMLENM 689
>PKN1_COREF (Q8FUI5) Probable serine/threonine protein kinase CE0033 (EC| 2.7.11.1) Length = 660 Score = 35.0 bits (79), Expect = 0.14 Identities = 14/39 (35%), Positives = 24/39 (61%) Frame = -1 Query: 551 TRSVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEIST 435 T +V+G+ Y++PE ARSD+Y+ G ++ E+ T Sbjct: 171 TAAVIGTAQYLSPEQARGKPADARSDVYAAGCVLYELVT 209
>MP2K2_CYPCA (Q90321) Dual specificity mitogen-activated protein kinase kinase 2| (EC 2.7.12.2) (MAP kinase kinase 2) (MAPKK 2) (ERK activator kinase 2) (MAPK/ERK kinase 2) (MEK2) Length = 397 Score = 35.0 bits (79), Expect = 0.14 Identities = 15/36 (41%), Positives = 25/36 (69%) Frame = -1 Query: 545 SVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEIS 438 S VG+ YM+PE L S +SD++S+GL ++E++ Sbjct: 223 SFVGTRSYMSPERLQGTHYSVQSDVWSMGLSLVELA 258
>E2AK3_RAT (Q9Z1Z1) Eukaryotic translation initiation factor 2-alpha kinase 3| precursor (EC 2.7.11.1) (PRKR-like endoplasmic reticulum kinase) (Pancreatic eIF2-alpha kinase) Length = 1108 Score = 34.7 bits (78), Expect = 0.18 Identities = 15/33 (45%), Positives = 23/33 (69%) Frame = -1 Query: 539 VGSVGYMAPEYLYNGEISARSDIYSLGLIIMEI 441 VG+ YM+PE ++ S + DI+SLGLI+ E+ Sbjct: 977 VGTKLYMSPEQIHGNNYSHKVDIFSLGLILFEL 1009
>E2AK3_HUMAN (Q9NZJ5) Eukaryotic translation initiation factor 2-alpha kinase 3| precursor (EC 2.7.11.1) (PRKR-like endoplasmic reticulum kinase) (Pancreatic eIF2-alpha kinase) (HsPEK) Length = 1115 Score = 34.7 bits (78), Expect = 0.18 Identities = 15/33 (45%), Positives = 23/33 (69%) Frame = -1 Query: 539 VGSVGYMAPEYLYNGEISARSDIYSLGLIIMEI 441 VG+ YM+PE ++ S + DI+SLGLI+ E+ Sbjct: 984 VGTKLYMSPEQIHGNSYSHKVDIFSLGLILFEL 1016
>STE7_YEAST (P06784) Serine/threonine-protein kinase STE7 (EC 2.7.12.2)| Length = 515 Score = 34.7 bits (78), Expect = 0.18 Identities = 15/35 (42%), Positives = 24/35 (68%) Frame = -1 Query: 539 VGSVGYMAPEYLYNGEISARSDIYSLGLIIMEIST 435 VG+ YM+PE + S + D++SLGL+I+E+ T Sbjct: 365 VGTSTYMSPERIQGNVYSIKGDVWSLGLMIIELVT 399
>INSR_AEDAE (Q93105) Insulin-like receptor precursor (EC 2.7.10.1) (MIR)| [Contains: Insulin-like receptor alpha chain; Insulin-like receptor beta chain] Length = 1390 Score = 34.7 bits (78), Expect = 0.18 Identities = 19/53 (35%), Positives = 31/53 (58%), Gaps = 2/53 (3%) Frame = -1 Query: 530 VGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMN--SSSTDQKHARKYIDG 378 V +MAPE L +G S+ SD++S G+++ E++T T+ + R IDG Sbjct: 1203 VRWMAPESLKDGIFSSSSDVFSYGVVLWEMATLASQPYQGLTNDQVLRYVIDG 1255
>IGF1R_RAT (P24062) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] Length = 1370 Score = 34.7 bits (78), Expect = 0.18 Identities = 32/129 (24%), Positives = 54/129 (41%), Gaps = 6/129 (4%) Frame = -1 Query: 530 VGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKENWTLEK 351 V +M+PE L +G + SD++S G+++ EI+T A + G+ L Sbjct: 1177 VRWMSPESLKDGVFTTHSDVWSFGVVLWEIATL-----------AEQPYQGLSNEQVLRF 1225 Query: 350 IMSEYIELEEHAFDQVEAC----INIGLQCVEIDQKKRPSIETIVNML--NKLPVSEEVS 189 +M E D+ + C + C + + K RPS I+ + P +EVS Sbjct: 1226 VM------EGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIIGSIKDEMEPSFQEVS 1279 Query: 188 HSM*AQNFP 162 +N P Sbjct: 1280 FYYSEENKP 1288
>PKN6_MYXXA (P54738) Serine/threonine-protein kinase pkn6 (EC 2.7.11.1)| Length = 710 Score = 34.7 bits (78), Expect = 0.18 Identities = 16/39 (41%), Positives = 23/39 (58%) Frame = -1 Query: 551 TRSVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEIST 435 T V G V YM PE L + R D+Y+LG+++ E+ T Sbjct: 176 TGVVKGKVAYMPPEQLQAKAMDRRVDVYALGVVLYELLT 214
>PKND_CHLCV (Q822K5) Serine/threonine-protein kinase pknD (EC 2.7.11.1)| Length = 930 Score = 34.7 bits (78), Expect = 0.18 Identities = 16/36 (44%), Positives = 24/36 (66%) Frame = -1 Query: 542 VVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEIST 435 +VG+ YMAPE L S +DIY+LG+I+ ++ T Sbjct: 191 IVGTPDYMAPERLRGTPASESTDIYALGVILYQMLT 226
>E2AK3_MOUSE (Q9Z2B5) Eukaryotic translation initiation factor 2-alpha kinase 3| precursor (EC 2.7.11.1) (PRKR-like endoplasmic reticulum kinase) (Pancreatic eIF2-alpha kinase) Length = 1114 Score = 34.7 bits (78), Expect = 0.18 Identities = 15/33 (45%), Positives = 23/33 (69%) Frame = -1 Query: 539 VGSVGYMAPEYLYNGEISARSDIYSLGLIIMEI 441 VG+ YM+PE ++ S + DI+SLGLI+ E+ Sbjct: 983 VGTKLYMSPEQIHGNNYSHKVDIFSLGLILFEL 1015
>PMYT1_CAEEL (O18209) Membrane-associated tyrosine- and threonine-specific| cdc2-inhibitory kinase (EC 2.7.11.1) (Myt1 kinase) (Lethal protein 37) Length = 677 Score = 34.7 bits (78), Expect = 0.18 Identities = 20/46 (43%), Positives = 27/46 (58%) Frame = -1 Query: 536 GSVGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKH 399 G Y+APE L NG + SDI+SLG+ I+E +T S+ D H Sbjct: 265 GDSKYLAPEVL-NGRPTKSSDIFSLGMTILEATTDLDVPSNGDSWH 309
>PKND_CHLPN (Q9Z986) Serine/threonine-protein kinase pknD (EC 2.7.11.1)| Length = 932 Score = 34.7 bits (78), Expect = 0.18 Identities = 15/36 (41%), Positives = 24/36 (66%) Frame = -1 Query: 542 VVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEIST 435 +VG+ YMAPE L S +DIY+LG+++ ++ T Sbjct: 190 IVGTPDYMAPERLLGHPASKSTDIYALGVVLYQMLT 225
>INSR_XENLA (Q9PVZ4) Insulin receptor precursor (EC 2.7.10.1) (IR) (Xe-InsR)| (XTK-1b) [Contains: Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1362 Score = 34.7 bits (78), Expect = 0.18 Identities = 32/129 (24%), Positives = 60/129 (46%), Gaps = 6/129 (4%) Frame = -1 Query: 530 VGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKENWTLEK 351 V +M+PE L +G +A SD++S G+++ EI++ A + G+ L+ Sbjct: 1189 VRWMSPESLKDGVFTAFSDVWSFGVVLWEITSL-----------AEQPYQGLSNEQVLKF 1237 Query: 350 IMSEYIELEEHAFDQVEAC----INIGLQCVEIDQKKRPSIETIVNML--NKLPVSEEVS 189 +M + + D E C ++ C + + K RP+ I++ML + P ++VS Sbjct: 1238 VM------DGGSLDHPENCPPRLHSLMQMCWQYNPKMRPTFLEIIDMLKDDLRPSFQDVS 1291 Query: 188 HSM*AQNFP 162 +N P Sbjct: 1292 FYYSDENKP 1300
>IGF1R_MOUSE (Q60751) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] Length = 1373 Score = 34.7 bits (78), Expect = 0.18 Identities = 32/129 (24%), Positives = 54/129 (41%), Gaps = 6/129 (4%) Frame = -1 Query: 530 VGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKENWTLEK 351 V +M+PE L +G + SD++S G+++ EI+T A + G+ L Sbjct: 1178 VRWMSPESLKDGVFTTHSDVWSFGVVLWEIATL-----------AEQPYQGLSNEQVLRF 1226 Query: 350 IMSEYIELEEHAFDQVEAC----INIGLQCVEIDQKKRPSIETIVNML--NKLPVSEEVS 189 +M E D+ + C + C + + K RPS I+ + P +EVS Sbjct: 1227 VM------EGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIIGSIKDEMEPSFQEVS 1280 Query: 188 HSM*AQNFP 162 +N P Sbjct: 1281 FYYSEENKP 1289
>MP2K5_HUMAN (Q13163) Dual specificity mitogen-activated protein kinase kinase 5| (EC 2.7.12.2) (MAP kinase kinase 5) (MAPKK 5) (MAPK/ERK kinase 5) Length = 438 Score = 34.3 bits (77), Expect = 0.24 Identities = 15/36 (41%), Positives = 23/36 (63%) Frame = -1 Query: 548 RSVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEI 441 ++ VG+ YMAPE + + SD++SLG+ MEI Sbjct: 314 KTYVGTNAYMAPERISGEQYGIHSDVWSLGISFMEI 349
>MKK1_YEAST (P32490) MAP kinase kinase MKK1/SSP32 (EC 2.7.12.2)| Length = 508 Score = 34.3 bits (77), Expect = 0.24 Identities = 17/41 (41%), Positives = 24/41 (58%) Frame = -1 Query: 536 GSVGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSS 414 G+ YMAPE + S SD++SLGL I+E++ SS Sbjct: 384 GTSFYMAPERIQGQPYSVTSDVWSLGLTILEVANGKFPCSS 424
>M3K7_MOUSE (Q62073) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1) Length = 579 Score = 34.3 bits (77), Expect = 0.24 Identities = 28/109 (25%), Positives = 45/109 (41%) Frame = -1 Query: 536 GSVGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKENWTL 357 GS +MAPE S + D++S G+I+ E+ TR R I N T Sbjct: 191 GSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFR--IMWAVHNGTR 248 Query: 356 EKIMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNKL 210 ++ + E ++ +C D +RPS+E IV ++ L Sbjct: 249 PPLIKNLPKPIE----------SLMTRCWSKDPSQRPSMEEIVKIMTHL 287
>M3K7_HUMAN (O43318) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1) Length = 606 Score = 34.3 bits (77), Expect = 0.24 Identities = 28/109 (25%), Positives = 45/109 (41%) Frame = -1 Query: 536 GSVGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKENWTL 357 GS +MAPE S + D++S G+I+ E+ TR R I N T Sbjct: 191 GSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFR--IMWAVHNGTR 248 Query: 356 EKIMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNKL 210 ++ + E ++ +C D +RPS+E IV ++ L Sbjct: 249 PPLIKNLPKPIE----------SLMTRCWSKDPSQRPSMEEIVKIMTHL 287
>CBK1_EMENI (P0C1B1) Serine/threonine-protein kinase cbk1 (EC 2.7.11.1)| Length = 884 Score = 34.3 bits (77), Expect = 0.24 Identities = 17/35 (48%), Positives = 22/35 (62%) Frame = -1 Query: 548 RSVVGSVGYMAPEYLYNGEISARSDIYSLGLIIME 444 RSVVG+ YMAPE + R D +SLG+I+ E Sbjct: 611 RSVVGTSQYMAPEVIRGHPYDGRCDWWSLGVILYE 645
>PKNB_BIFLO (Q8G6P9) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 690 Score = 34.3 bits (77), Expect = 0.24 Identities = 14/39 (35%), Positives = 24/39 (61%) Frame = -1 Query: 551 TRSVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEIST 435 ++ VVG+ Y++PE + RSD+YS G ++ E+ T Sbjct: 181 SQGVVGTAQYLSPEQARGETVDMRSDLYSAGCVLYEMLT 219
>INSRR_CAVPO (P14617) Insulin receptor-related protein precursor (EC 2.7.10.1)| (IRR) (IR-related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain] Length = 1300 Score = 34.3 bits (77), Expect = 0.24 Identities = 28/110 (25%), Positives = 51/110 (46%), Gaps = 4/110 (3%) Frame = -1 Query: 530 VGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKENWTLEK 351 V +MAPE L +G + SD++S G+++ EI T A + G+ L+ Sbjct: 1156 VRWMAPESLKDGIFTTHSDVWSFGVVLWEIVTL-----------AEQPYQGLSNEQVLKF 1204 Query: 350 IMSEYI--ELEE--HAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNK 213 +M + ELE+ H ++ + C + + + RP+ I+N + K Sbjct: 1205 VMDGGVLEELEDCPHQLQELMS------SCWQQNPRLRPTFTQILNSIQK 1248
>GPRK2_DROME (P32866) G protein-coupled receptor kinase 2 (EC 2.7.11.16)| Length = 714 Score = 33.9 bits (76), Expect = 0.31 Identities = 21/62 (33%), Positives = 33/62 (53%), Gaps = 1/62 (1%) Frame = -1 Query: 548 RSVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYID-GVK 372 R VG+VGYMAPE + N + + D +S G ++ E+ +K R+ +D VK Sbjct: 467 RGRVGTVGYMAPEVIDNEKYAFSPDWFSFGCLLYEMIEGQAPFRMRKEKVKREEVDRRVK 526 Query: 371 EN 366 E+ Sbjct: 527 ED 528
>MERTK_RAT (P57097) Proto-oncogene tyrosine-protein kinase MER precursor (EC| 2.7.10.1) (C-mer) (Receptor tyrosine kinase MerTK) Length = 994 Score = 33.9 bits (76), Expect = 0.31 Identities = 30/114 (26%), Positives = 48/114 (42%), Gaps = 4/114 (3%) Frame = -1 Query: 530 VGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKENWTLEK 351 V ++A E L + +++SD+++ G+ + EI+TR M Q H Sbjct: 759 VKWIAIESLADRVYTSKSDVWAFGVTMWEIATRGMTPYPGVQNHE--------------- 803 Query: 350 IMSEYIELEEHAFDQVEACIN----IGLQCVEIDQKKRPSIETIVNMLNKLPVS 201 M +Y+ L H Q E C++ I C D RP+ + L KL S Sbjct: 804 -MYDYL-LHGHRLKQPEDCLDDLYEIMYSCWSADPLDRPTFSVLRLQLEKLSES 855
>MERTK_MOUSE (Q60805) Proto-oncogene tyrosine-protein kinase MER precursor (EC| 2.7.10.1) (C-mer) (Receptor tyrosine kinase MerTK) Length = 994 Score = 33.9 bits (76), Expect = 0.31 Identities = 30/114 (26%), Positives = 48/114 (42%), Gaps = 4/114 (3%) Frame = -1 Query: 530 VGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKENWTLEK 351 V ++A E L + +++SD+++ G+ + EI+TR M Q H Sbjct: 759 VKWIAIESLADRVYTSKSDVWAFGVTMWEITTRGMTPYPGVQNHE--------------- 803 Query: 350 IMSEYIELEEHAFDQVEACI----NIGLQCVEIDQKKRPSIETIVNMLNKLPVS 201 M +Y+ L H Q E C+ +I C D RP+ + L KL S Sbjct: 804 -MYDYL-LHGHRLKQPEDCLDELYDIMYSCWSADPLDRPTFSVLRLQLEKLSES 855
>NEK2_HUMAN (P51955) Serine/threonine-protein kinase Nek2 (EC 2.7.11.1)| (NimA-related protein kinase 2) (NimA-like protein kinase 1) (HSPK 21) Length = 445 Score = 33.9 bits (76), Expect = 0.31 Identities = 29/127 (22%), Positives = 61/127 (48%), Gaps = 7/127 (5%) Frame = -1 Query: 548 RSVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKH-ARKYIDG-- 378 ++ VG+ YM+PE + + +SDI+SLG ++ E+ ++ QK A K +G Sbjct: 174 KTFVGTPYYMSPEQMNRMSYNEKSDIWSLGCLLYELCALMPPFTAFSQKELAGKIREGKF 233 Query: 377 ----VKENWTLEKIMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNKL 210 + + L +I++ + L+++ VE + L + ++R ++E L + Sbjct: 234 RRIPYRYSDELNEIITRMLNLKDYHRPSVEEILENPLIADLVADEQRRNLERRGRQLGEP 293 Query: 209 PVSEEVS 189 S++ S Sbjct: 294 EKSQDSS 300
>MP2K5_RAT (Q62862) Dual specificity mitogen-activated protein kinase kinase 5| (EC 2.7.12.2) (MAP kinase kinase 5) (MAPKK 5) (MAPK/ERK kinase 5) Length = 448 Score = 33.9 bits (76), Expect = 0.31 Identities = 14/37 (37%), Positives = 24/37 (64%) Frame = -1 Query: 548 RSVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEIS 438 ++ VG+ YMAPE + + SD++SLG+ ME++ Sbjct: 314 KTYVGTNAYMAPERISGEQYGIHSDVWSLGISFMELA 350
>MP2K5_MOUSE (Q9WVS7) Dual specificity mitogen-activated protein kinase kinase 5| (EC 2.7.12.2) (MAP kinase kinase 5) (MAPKK 5) (MAPK/ERK kinase 5) Length = 448 Score = 33.9 bits (76), Expect = 0.31 Identities = 14/37 (37%), Positives = 24/37 (64%) Frame = -1 Query: 548 RSVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEIS 438 ++ VG+ YMAPE + + SD++SLG+ ME++ Sbjct: 314 KTYVGTNAYMAPERISGEQYGIHSDVWSLGISFMELA 350
>FPS_DROME (P18106) Tyrosine-protein kinase Fps85D (EC 2.7.10.2) (dFer)| Length = 1325 Score = 33.9 bits (76), Expect = 0.31 Identities = 30/116 (25%), Positives = 50/116 (43%), Gaps = 1/116 (0%) Frame = -1 Query: 530 VGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNS-SSTDQKHARKYIDGVKENWTLE 354 V + APE L G+ ++ D++S G+++ EI ++ S AR+ ID T + Sbjct: 1224 VKWTAPEALNFGKYTSLCDVWSYGILMWEIFSKGDTPYSGMTNSRARERIDTGYRMPTPK 1283 Query: 353 KIMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNKLPVSEEVSH 186 E L LQC D + RP + I N+++ L + + SH Sbjct: 1284 STPEEMYRLM--------------LQCWAADAESRPHFDEIYNVVDALILRLDNSH 1325
>KPK2_PLAFK (Q02595) Probable serine/threonine-protein kinase 2 (EC 2.7.11.1)| Length = 510 Score = 33.9 bits (76), Expect = 0.31 Identities = 21/63 (33%), Positives = 31/63 (49%), Gaps = 5/63 (7%) Frame = -1 Query: 536 GSVGYMAPEYLYNGEISARSDIYSLGLIIMEI-----STRXMNSSSTDQKHARKYIDGVK 372 GS GY+APE L + DI+SLG+I+ I R N +K+ R +I Sbjct: 268 GSPGYVAPEILKCASYGTKVDIFSLGVILFNILCGYPPFRGNNVKEIFKKNMRCHISFNT 327 Query: 371 ENW 363 ++W Sbjct: 328 KHW 330
>TMKL1_ARATH (P33543) Putative kinase-like protein TMKL1 precursor| Length = 674 Score = 33.9 bits (76), Expect = 0.31 Identities = 27/115 (23%), Positives = 52/115 (45%), Gaps = 8/115 (6%) Frame = -1 Query: 533 SVGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYID-------GV 375 S GY APE + + RSD+Y+ G++++EI S ++ +++D V Sbjct: 539 SDGYKAPELHKMKKCNPRSDVYAFGILLLEILMGKKPGKS--GRNGNEFVDLPSLVKAAV 596 Query: 374 KENWTLEKIMSEYIE-LEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNK 213 E T+E E ++ + + + + + + C RPS+E +V L + Sbjct: 597 LEETTMEVFDLEAMKGIRSPMEEGLVHALKLAMGCCAPVTTVRPSMEEVVKQLEE 651
>FUZ7_USTMA (Q99078) Dual specificity protein kinase FUZ7 (EC 2.7.12.2)| Length = 435 Score = 33.9 bits (76), Expect = 0.31 Identities = 13/34 (38%), Positives = 25/34 (73%) Frame = -1 Query: 539 VGSVGYMAPEYLYNGEISARSDIYSLGLIIMEIS 438 VG+ YM+PE + + S +SD++SLG+ I++++ Sbjct: 265 VGTSTYMSPERIQGDQYSVKSDVWSLGVSIIDVA 298
>ROS_HUMAN (P08922) Proto-oncogene tyrosine-protein kinase ROS precursor (EC| 2.7.10.1) (c-ros-1) Length = 2347 Score = 33.9 bits (76), Expect = 0.31 Identities = 15/32 (46%), Positives = 23/32 (71%) Frame = -1 Query: 530 VGYMAPEYLYNGEISARSDIYSLGLIIMEIST 435 V +MAPE L +G + +SD++S G++I EI T Sbjct: 2125 VRWMAPESLMDGIFTTQSDVWSFGILIWEILT 2156
>SRK3_SPOLA (P42689) Tyrosine-protein kinase SRK3 (EC 2.7.10.2) (Fragment)| Length = 334 Score = 33.9 bits (76), Expect = 0.31 Identities = 29/111 (26%), Positives = 47/111 (42%), Gaps = 1/111 (0%) Frame = -1 Query: 530 VGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKENWTLEK 351 + + APE + +SD++S G++I EI T H R G+ LE Sbjct: 226 IKWTAPEAALYNRFTIKSDVWSFGVLISEIVT-----------HGRMPYPGMTNRQVLEA 274 Query: 350 IMSEY-IELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNKLPVS 201 + Y + E D + I L C + + RP+ E++ N+L VS Sbjct: 275 VDRGYRMPCPEGCPDPL---YKIMLSCWKHEPDDRPTFESLKNLLEDYYVS 322
>EPA4A_BRARE (O13148) Ephrin type-A receptor 4a (EC 2.7.10.1) (Tyrosine-protein| kinase receptor ZEK2) (EPH-like kinase 2) (Fragment) Length = 292 Score = 33.9 bits (76), Expect = 0.31 Identities = 25/107 (23%), Positives = 51/107 (47%) Frame = -1 Query: 530 VGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKENWTLEK 351 + + APE + + ++ SD++S G+++ E+ + D + + I ++E + L Sbjct: 171 IRWTAPEAITYRKFTSASDVWSYGIVMWEVMSYG-ERPYWDMSN-QDVIKAIEEGYRLPP 228 Query: 350 IMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNKL 210 M + L + + L C + ++ +RP IVNML+KL Sbjct: 229 PMDCPVSLHQ-----------LMLDCWQKERAERPKFSQIVNMLDKL 264
>CSF1R_HUMAN (P07333) Macrophage colony-stimulating factor 1 receptor precursor| (CSF-1-R) (EC 2.7.10.1) (Fms proto-oncogene) (c-fms) (CD115 antigen) Length = 972 Score = 33.9 bits (76), Expect = 0.31 Identities = 23/106 (21%), Positives = 51/106 (48%) Frame = -1 Query: 530 VGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKENWTLEK 351 V +MAPE +++ + +SD++S G+++ EI + +N G+ N K Sbjct: 819 VKWMAPESIFDCVYTVQSDVWSYGILLWEIFSLGLNP-----------YPGILVNSKFYK 867 Query: 350 IMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNK 213 ++ + ++ + AF + +I C ++ RP+ + I + L + Sbjct: 868 LVKDGYQMAQPAF-APKNIYSIMQACWALEPTHRPTFQQICSFLQE 912
>WIS4_SCHPO (O14299) MAP kinase kinase kinase wis4 (EC 2.7.11.25) (MAP kinase| kinase kinase wak1) (MAP kinase kinase kinase wik1) Length = 1401 Score = 33.9 bits (76), Expect = 0.31 Identities = 29/108 (26%), Positives = 46/108 (42%), Gaps = 9/108 (8%) Frame = -1 Query: 542 VVGSVGYMAPEYLYN---GEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKY----- 387 + G+ YMAPE + G+ A DI+SLG +I+E+ T S D + A Y Sbjct: 1206 LAGTPMYMAPEIILGTKKGDFGAM-DIWSLGCVILEMMTGSTPWSEMDNEWAIMYHVAAM 1264 Query: 386 -IDGVKENWTLEKIMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRP 246 + +N + + ++IE QC E D ++RP Sbjct: 1265 HTPSIPQNEKISSLARDFIE-----------------QCFERDPEQRP 1295
>NEK6_RAT (P59895) Serine/threonine-protein kinase Nek6 (EC 2.7.11.1)| (NimA-related protein kinase 6) Length = 313 Score = 33.9 bits (76), Expect = 0.31 Identities = 29/116 (25%), Positives = 56/116 (48%), Gaps = 2/116 (1%) Frame = -1 Query: 545 SVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKEN 366 S+VG+ YM+PE ++ + +SDI+SLG ++ E++ + Y D + Sbjct: 206 SLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAA----------LQSPFYGDKMNLF 255 Query: 365 WTLEKI-MSEYIELE-EHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNKLPV 204 +KI +Y L EH +++ +++ C+ D RP IE + + ++ V Sbjct: 256 SLCQKIEQCDYPPLPGEHYSEKLRELVSM---CIYPDPNHRPDIEYVHQVAKQMHV 308
>KIT_FSVHZ (P04048) Tyrosine-protein kinase transforming protein kit (EC| 2.7.10.1) Length = 370 Score = 33.9 bits (76), Expect = 0.31 Identities = 27/106 (25%), Positives = 50/106 (47%) Frame = -1 Query: 530 VGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKENWTLEK 351 V +MAPE ++N + SD++S G+ + E+ + +S K+ +KE + + Sbjct: 271 VKWMAPESIFNCVYTFESDVWSYGIFLWELFSLG-SSPYPGMPVDSKFYKMIKEGFRMLS 329 Query: 350 IMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNK 213 EHA ++ +I C + D KRP+ + IV ++ K Sbjct: 330 --------PEHAPAEM---YDIMKTCWDADPLKRPTFKQIVQLIEK 364
>CSF1R_MOUSE (P09581) Macrophage colony-stimulating factor 1 receptor precursor| (CSF-1-R) (EC 2.7.10.1) (Fms proto-oncogene) (c-fms) Length = 977 Score = 33.9 bits (76), Expect = 0.31 Identities = 22/106 (20%), Positives = 52/106 (49%) Frame = -1 Query: 530 VGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKENWTLEK 351 V +MAPE +++ + +SD++S G+++ EI + +N G+ N K Sbjct: 817 VKWMAPESIFDCVYTVQSDVWSYGILLWEIFSLGLNP-----------YPGILVNNKFYK 865 Query: 350 IMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNK 213 ++ + ++ + F + +I C +++ +RP+ + I +L + Sbjct: 866 LVKDGYQMAQPVF-APKNIYSIMQSCWDLEPTRRPTFQQICFLLQE 910
>MEK2_CAEEL (Q10664) Dual specificity mitogen-activated protein kinase kinase| mek-2 (EC 2.7.12.2) (MAP kinase kinase mek-2) Length = 387 Score = 33.5 bits (75), Expect = 0.41 Identities = 16/35 (45%), Positives = 22/35 (62%) Frame = -1 Query: 545 SVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEI 441 S VG+ YMAPE L + SDI+S GL ++E+ Sbjct: 227 SFVGTRSYMAPERLTGSHYTISSDIWSFGLSLVEL 261
>KPCD1_HUMAN (Q15139) Serine/threonine-protein kinase D1 (EC 2.7.11.13)| (nPKC-D1) (Protein kinase D) (Protein kinase C mu type) (nPKC-mu) Length = 912 Score = 33.5 bits (75), Expect = 0.41 Identities = 16/33 (48%), Positives = 23/33 (69%) Frame = -1 Query: 548 RSVVGSVGYMAPEYLYNGEISARSDIYSLGLII 450 RSVVG+ Y+APE L N + D++S+G+II Sbjct: 741 RSVVGTPAYLAPEVLRNKGYNRSLDMWSVGVII 773
>EPHA3_HUMAN (P29320) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ETK1) (HEK) (HEK4) Length = 983 Score = 33.5 bits (75), Expect = 0.41 Identities = 25/107 (23%), Positives = 48/107 (44%) Frame = -1 Query: 530 VGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKENWTLEK 351 + + +PE + + ++ SD++S G+++ E+ + + + I V E + L Sbjct: 788 IRWTSPEAIAYRKFTSASDVWSYGIVLWEVMS--YGERPYWEMSNQDVIKAVDEGYRLPP 845 Query: 350 IMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNKL 210 M D A + L C + D+ RP E IV++L+KL Sbjct: 846 PM-----------DCPAALYQLMLDCWQKDRNNRPKFEQIVSILDKL 881
>ATG1_BOTCI (Q6H9I1) Serine/threonine-protein kinase ATG1 (EC 2.7.11.1)| (Autophagy-related protein 1) (Botryotinia fuckeliana putative kinase exons 1-3) Length = 952 Score = 33.5 bits (75), Expect = 0.41 Identities = 15/37 (40%), Positives = 25/37 (67%) Frame = -1 Query: 545 SVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEIST 435 ++ GS YMAPE L + AR+D++S+G ++ E+ T Sbjct: 230 TLCGSPLYMAPEILRYEKYDARADLWSIGTVLYEMMT 266
>PKN3_MYXXA (Q9XBQ0) Serine/threonine-protein kinase pkn3 (EC 2.7.11.1)| Length = 547 Score = 33.5 bits (75), Expect = 0.41 Identities = 13/36 (36%), Positives = 24/36 (66%) Frame = -1 Query: 542 VVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEIST 435 V G+ YM+PE ++ RSD+Y++G+I+ ++ T Sbjct: 186 VCGTPEYMSPEQARGSQLDHRSDLYAVGVILYQLMT 221
>MATK_MOUSE (P41242) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK) Length = 505 Score = 33.5 bits (75), Expect = 0.41 Identities = 13/30 (43%), Positives = 22/30 (73%) Frame = -1 Query: 530 VGYMAPEYLYNGEISARSDIYSLGLIIMEI 441 V + APE L NG S++SD++S G+++ E+ Sbjct: 386 VKWTAPEALKNGRFSSKSDVWSFGVLLWEV 415
>ACV1B_RAT (P80202) Activin receptor type 1B precursor (EC 2.7.11.30)| (ACTR-IB) (Serine/threonine-protein kinase receptor R2) (SKR2) Length = 505 Score = 33.5 bits (75), Expect = 0.41 Identities = 24/71 (33%), Positives = 40/71 (56%), Gaps = 7/71 (9%) Frame = -1 Query: 539 VGSVGYMAPEYLYNGEISAR-------SDIYSLGLIIMEISTRXMNSSSTDQKHARKYID 381 VG+ YMAPE L + I+ + +DIY+LGL+ EI+ R NS +++ Y D Sbjct: 375 VGTKRYMAPEVL-DETINMKHFDSFKCADIYALGLVYWEIA-RRCNSGGVHEEYQLPYYD 432 Query: 380 GVKENWTLEKI 348 V + ++E++ Sbjct: 433 LVPSDPSIEEM 443
>ACV1B_HUMAN (P36896) Activin receptor type 1B precursor (EC 2.7.11.30)| (ACTR-IB) (Serine/threonine-protein kinase receptor R2) (SKR2) (Activin receptor-like kinase 4) (ALK-4) Length = 505 Score = 33.5 bits (75), Expect = 0.41 Identities = 24/71 (33%), Positives = 40/71 (56%), Gaps = 7/71 (9%) Frame = -1 Query: 539 VGSVGYMAPEYLYNGEISAR-------SDIYSLGLIIMEISTRXMNSSSTDQKHARKYID 381 VG+ YMAPE L + I+ + +DIY+LGL+ EI+ R NS +++ Y D Sbjct: 375 VGTKRYMAPEVL-DETINMKHFDSFKCADIYALGLVYWEIA-RRCNSGGVHEEYQLPYYD 432 Query: 380 GVKENWTLEKI 348 V + ++E++ Sbjct: 433 LVPSDPSIEEM 443
>PGFRA_XENLA (P26619) Alpha platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-alpha) Length = 1087 Score = 33.5 bits (75), Expect = 0.41 Identities = 26/108 (24%), Positives = 52/108 (48%), Gaps = 1/108 (0%) Frame = -1 Query: 530 VGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKENWTLEK 351 V +MAPE +++ + SD++S G+++ EI + Y + ++ K Sbjct: 859 VKWMAPESIFDNLYTTLSDVWSFGILLWEIFSLG----------GTPYPGMIVDSTFYNK 908 Query: 350 IMSEY-IELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNKL 210 I S Y + +HA +V +I ++C + +KRPS + +++ L Sbjct: 909 IKSGYRMAKPDHATHEV---YDIMVKCWNSEPEKRPSFRHLSDIVESL 953
>IKKB_DROME (Q9VEZ5) Inhibitor of nuclear factor kappa B kinase beta subunit| (EC 2.7.11.1) (DmIKK-beta) (Immune response deficient protein 5) (IKK-like protein) (Lipopolysaccharide-activated kinase) (DLAK) (Cactus kinase IKK) Length = 751 Score = 33.5 bits (75), Expect = 0.41 Identities = 16/38 (42%), Positives = 25/38 (65%) Frame = -1 Query: 548 RSVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEIST 435 +SVVG+ Y APE + NG ++ D++S G+I E+ T Sbjct: 220 QSVVGTRHYYAPEVVENGFYNSTVDLWSFGVIAYELVT 257
>MATK_RAT (P41243) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase BATK) Length = 467 Score = 33.5 bits (75), Expect = 0.41 Identities = 13/30 (43%), Positives = 22/30 (73%) Frame = -1 Query: 530 VGYMAPEYLYNGEISARSDIYSLGLIIMEI 441 V + APE L NG S++SD++S G+++ E+ Sbjct: 348 VKWTAPEALKNGRFSSKSDVWSFGVLLWEV 377
>KPCD1_MOUSE (Q62101) Serine/threonine-protein kinase D1 (EC 2.7.11.13)| (nPKC-D1) (Protein kinase D) (Protein kinase C mu type) (nPKC-mu) Length = 918 Score = 33.5 bits (75), Expect = 0.41 Identities = 16/33 (48%), Positives = 23/33 (69%) Frame = -1 Query: 548 RSVVGSVGYMAPEYLYNGEISARSDIYSLGLII 450 RSVVG+ Y+APE L N + D++S+G+II Sbjct: 747 RSVVGTPAYLAPEVLRNKGYNRSLDMWSVGVII 779
>CCAMK_LILLO (Q43531) Calcium and calcium/calmodulin-dependent| serine/threonine-protein kinase (EC 2.7.11.17) (LlCCaMK) Length = 520 Score = 33.5 bits (75), Expect = 0.41 Identities = 13/32 (40%), Positives = 25/32 (78%) Frame = -1 Query: 545 SVVGSVGYMAPEYLYNGEISARSDIYSLGLII 450 ++ GS+ Y++PE L ++S+ SD++SLG+I+ Sbjct: 203 ALFGSIDYVSPEALSQRQVSSASDMWSLGVIL 234
>GRK4_HUMAN (P32298) G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK4) (ITI1) Length = 578 Score = 33.5 bits (75), Expect = 0.41 Identities = 16/36 (44%), Positives = 23/36 (63%) Frame = -1 Query: 548 RSVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEI 441 R VG+VGYMAPE + N + + D + LG +I E+ Sbjct: 344 RGRVGTVGYMAPEVVNNEKYTFSPDWWGLGCLIYEM 379
>NIM1_NEUCR (P48479) G2-specific protein kinase nim-1 (EC 2.7.11.1)| Length = 779 Score = 33.5 bits (75), Expect = 0.41 Identities = 27/106 (25%), Positives = 49/106 (46%) Frame = -1 Query: 539 VGSVGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKENWT 360 VG+ YM+PE + + +SDI+SLG II E+ R + K + + +KE Sbjct: 196 VGTPFYMSPEICAAEKYTLKSDIWSLGCIIYELCAR---EPPFNAKTHYQLVQKIKEG-K 251 Query: 359 LEKIMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNM 222 + + S Y F ++ C+ ++ +RP T++N+ Sbjct: 252 IAPLPSVY---SGELFATIK-------DCLRVNPDRRPDTATLLNL 287
>PKN1_MYXXA (P33973) Serine/threonine-protein kinase pkn1 (EC 2.7.11.1)| Length = 693 Score = 33.5 bits (75), Expect = 0.41 Identities = 14/36 (38%), Positives = 23/36 (63%) Frame = -1 Query: 542 VVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEIST 435 +VG+ YMAPE + R+D+Y+LG+I ++ T Sbjct: 221 IVGTPEYMAPEQSLGRGVDGRADLYALGVIAYQLLT 256
>NEK6_MOUSE (Q9ES70) Serine/threonine-protein kinase Nek6 (EC 2.7.11.1)| (NimA-related protein kinase 6) Length = 313 Score = 33.5 bits (75), Expect = 0.41 Identities = 14/36 (38%), Positives = 26/36 (72%) Frame = -1 Query: 545 SVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEIS 438 S+VG+ YM+PE ++ + +SDI+SLG ++ E++ Sbjct: 206 SLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMA 241
>NEK6_HUMAN (Q9HC98) Serine/threonine-protein kinase Nek6 (EC 2.7.11.1)| (NimA-related protein kinase 6) (Protein kinase SID6-1512) Length = 313 Score = 33.5 bits (75), Expect = 0.41 Identities = 14/36 (38%), Positives = 26/36 (72%) Frame = -1 Query: 545 SVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEIS 438 S+VG+ YM+PE ++ + +SDI+SLG ++ E++ Sbjct: 206 SLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMA 241
>PDPK1_CAEEL (Q9Y1J3) 3-phophoinositide-dependent protein kinase 1 (EC 2.7.11.1)| (Pdk-class protein kinase protein 1) Length = 636 Score = 33.5 bits (75), Expect = 0.41 Identities = 16/52 (30%), Positives = 29/52 (55%) Frame = -1 Query: 539 VGSVGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYI 384 VG+ Y++PE L +G++ ++DI+ LG I+ + + +Q H K I Sbjct: 271 VGTALYVSPEMLADGDVGPQTDIWGLGCILFQCLAGQPPFRAVNQYHLLKRI 322
>LIMK1_HUMAN (P53667) LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1)| Length = 647 Score = 33.1 bits (74), Expect = 0.54 Identities = 26/113 (23%), Positives = 52/113 (46%), Gaps = 1/113 (0%) Frame = -1 Query: 545 SVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYID-GVKE 369 +VVG+ +MAPE + + D++S G+++ EI R + D + + +D G+ Sbjct: 508 TVVGNPYWMAPEMINGRSYDEKVDVFSFGIVLCEIIGRV----NADPDYLPRTMDFGLNV 563 Query: 368 NWTLEKIMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNKL 210 L++ + + I ++C ++D +KRPS + + L L Sbjct: 564 RGFLDRYCPP---------NCPPSFFPITVRCCDLDPEKRPSFVKLEHWLETL 607
>EPHA2_HUMAN (P29317) Ephrin type-A receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) Length = 976 Score = 33.1 bits (74), Expect = 0.54 Identities = 25/107 (23%), Positives = 51/107 (47%) Frame = -1 Query: 530 VGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKENWTLEK 351 + + APE + + ++ SD++S G+++ E+ T R Y + N + K Sbjct: 781 IRWTAPEAISYRKFTSASDVWSFGIVMWEVMTYG----------ERPYWE--LSNHEVMK 828 Query: 350 IMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNKL 210 +++ L D A + +QC + ++ +RP IV++L+KL Sbjct: 829 AINDGFRLPT-PMDCPSAIYQLMMQCWQQERARRPKFADIVSILDKL 874
>IGF1R_HUMAN (P08069) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 recepto Length = 1367 Score = 33.1 bits (74), Expect = 0.54 Identities = 26/110 (23%), Positives = 48/110 (43%), Gaps = 4/110 (3%) Frame = -1 Query: 530 VGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKENWTLEK 351 V +M+PE L +G + SD++S G+++ EI+T A + G+ L Sbjct: 1176 VRWMSPESLKDGVFTTYSDVWSFGVVLWEIATL-----------AEQPYQGLSNEQVLRF 1224 Query: 350 IMSEYIELEEHAFDQVEAC----INIGLQCVEIDQKKRPSIETIVNMLNK 213 +M E D+ + C + C + + K RPS I++ + + Sbjct: 1225 VM------EGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIKE 1268
>AVR2B_MOUSE (P27040) Activin receptor type 2B precursor (EC 2.7.11.30) (Activin| receptor type IIB) (ACTR-IIB) Length = 536 Score = 33.1 bits (74), Expect = 0.54 Identities = 31/112 (27%), Positives = 51/112 (45%), Gaps = 7/112 (6%) Frame = -1 Query: 551 TRSVVGSVGYMAPEYL-----YNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKY 387 T VG+ YMAPE L + + R D+Y++GL++ E+ +R K Sbjct: 379 THGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELVSRC------------KA 426 Query: 386 IDGVKENWTL--EKIMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIE 237 DG + + L E+ + ++ LEE LQ V + +K RP+I+ Sbjct: 427 ADGPVDEYMLPFEEEIGQHPSLEE-------------LQEVVVHKKMRPTIK 465
>AVR2B_RAT (P38445) Activin receptor type 2B precursor (EC 2.7.11.30) (Activin| receptor type IIB) (ACTR-IIB) Length = 513 Score = 33.1 bits (74), Expect = 0.54 Identities = 31/112 (27%), Positives = 51/112 (45%), Gaps = 7/112 (6%) Frame = -1 Query: 551 TRSVVGSVGYMAPEYL-----YNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKY 387 T VG+ YMAPE L + + R D+Y++GL++ E+ +R K Sbjct: 356 THGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELVSRC------------KA 403 Query: 386 IDGVKENWTL--EKIMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIE 237 DG + + L E+ + ++ LEE LQ V + +K RP+I+ Sbjct: 404 ADGPVDEYMLPFEEEIGQHPSLEE-------------LQEVVVHKKMRPTIK 442
>MP2K1_PANTR (Q9XT09) Dual specificity mitogen-activated protein kinase kinase 1| (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) Length = 392 Score = 33.1 bits (74), Expect = 0.54 Identities = 18/48 (37%), Positives = 26/48 (54%) Frame = -1 Query: 545 SVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQK 402 S VG+ YM+PE S +SDI+S+GL +E++ S D K Sbjct: 221 SFVGTRSYMSPERFQGTHYSVQSDIWSMGLSPVEMAVGRYPIPSPDAK 268
>KIT_MOUSE (P05532) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 975 Score = 33.1 bits (74), Expect = 0.54 Identities = 26/115 (22%), Positives = 54/115 (46%) Frame = -1 Query: 530 VGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKENWTLEK 351 V +MAPE +++ + SD++S G+ + E+ + +S K+ +KE + + Sbjct: 831 VKWMAPESIFSCVYTFESDVWSYGIFLWELFSLG-SSPYPGMPVDSKFYKMIKEGFRMVS 889 Query: 350 IMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNKLPVSEEVSH 186 EHA ++ ++ C + D KRP+ + +V ++ K +S+ H Sbjct: 890 --------PEHAPAEM---YDVMKTCWDADPLKRPTFKQVVQLIEK-QISDSTKH 932
>PKN2_COREF (Q8FUI4) Serine/threonine protein kinases drp72 (EC 2.7.11.1)| Length = 520 Score = 33.1 bits (74), Expect = 0.54 Identities = 14/37 (37%), Positives = 24/37 (64%) Frame = -1 Query: 551 TRSVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEI 441 T VVG+ Y++PE +++ SD+YSLG++ E+ Sbjct: 181 TGMVVGTAQYVSPEQAQGHQVTPASDVYSLGVVGYEM 217
>AVR2B_HUMAN (Q13705) Activin receptor type 2B precursor (EC 2.7.11.30) (Activin| receptor type IIB) (ACTR-IIB) Length = 512 Score = 33.1 bits (74), Expect = 0.54 Identities = 31/112 (27%), Positives = 51/112 (45%), Gaps = 7/112 (6%) Frame = -1 Query: 551 TRSVVGSVGYMAPEYL-----YNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKY 387 T VG+ YMAPE L + + R D+Y++GL++ E+ +R K Sbjct: 355 THGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELVSRC------------KA 402 Query: 386 IDGVKENWTL--EKIMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIE 237 DG + + L E+ + ++ LEE LQ V + +K RP+I+ Sbjct: 403 ADGPVDEYMLPFEEEIGQHPSLEE-------------LQEVVVHKKMRPTIK 441
>AVR2B_BOVIN (Q95126) Activin receptor type 2B precursor (EC 2.7.11.30) (Activin| receptor type IIB) (ACTR-IIB) Length = 512 Score = 33.1 bits (74), Expect = 0.54 Identities = 31/112 (27%), Positives = 51/112 (45%), Gaps = 7/112 (6%) Frame = -1 Query: 551 TRSVVGSVGYMAPEYL-----YNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKY 387 T VG+ YMAPE L + + R D+Y++GL++ E+ +R K Sbjct: 355 THGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELVSRC------------KA 402 Query: 386 IDGVKENWTL--EKIMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIE 237 DG + + L E+ + ++ LEE LQ V + +K RP+I+ Sbjct: 403 ADGPVDEYMLPFEEEIGQHPSLEE-------------LQEVVVHKKMRPAIK 441
>AVR2A_XENLA (P27039) Activin receptor type 2A precursor (EC 2.7.11.30) (Activin| receptor type II) (ACTR-II) Length = 514 Score = 33.1 bits (74), Expect = 0.54 Identities = 20/71 (28%), Positives = 37/71 (52%), Gaps = 5/71 (7%) Frame = -1 Query: 551 TRSVVGSVGYMAPEYL-----YNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKY 387 T VG+ YMAPE L + + R D+Y+ GL++ E+++R S ++ + Sbjct: 357 THGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAFGLVLWELASRCTASDGPVDEYMLPF 416 Query: 386 IDGVKENWTLE 354 + V ++ +LE Sbjct: 417 EEEVGQHPSLE 427
>PKWA_THECU (P49695) Probable serine/threonine-protein kinase pkwA (EC| 2.7.11.1) Length = 742 Score = 33.1 bits (74), Expect = 0.54 Identities = 12/37 (32%), Positives = 24/37 (64%) Frame = -1 Query: 545 SVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEIST 435 +V+G++ YM+PE ++ SD++SLG ++ +T Sbjct: 172 AVIGTLAYMSPEQTDGSQVGPASDVFSLGTVLAFAAT 208
>IGF1R_BOVIN (Q05688) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] (F Length = 640 Score = 33.1 bits (74), Expect = 0.54 Identities = 26/106 (24%), Positives = 46/106 (43%), Gaps = 4/106 (3%) Frame = -1 Query: 530 VGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKENWTLEK 351 V +M+PE L +G + SD++S G+++ EI+T A + G+ L Sbjct: 449 VRWMSPESLKDGVFTTHSDVWSFGVVLWEIATL-----------AEQPYQGLSNEQVLRF 497 Query: 350 IMSEYIELEEHAFDQVEAC----INIGLQCVEIDQKKRPSIETIVN 225 +M E D+ + C + C + + K RPS I++ Sbjct: 498 VM------EGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIIS 537
>DAF4_CAEEL (P50488) Cell-surface receptor daf-4 precursor (EC 2.7.11.30)| (Abnormal dauer formation protein 4) Length = 744 Score = 33.1 bits (74), Expect = 0.54 Identities = 35/145 (24%), Positives = 56/145 (38%), Gaps = 26/145 (17%) Frame = -1 Query: 539 VGSVGYMAPEYL-----YNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKH-------- 399 VG+ YM+PE L + D+YS+GL++ E+ +R + + + Sbjct: 478 VGTKRYMSPEMLEGATEFTPTAFKAMDVYSMGLVMWEVISRTKLHQTDEPPNYQMPFQVI 537 Query: 398 --------ARKYIDGVKE--NWTLEKIMSEYIELEEHAFDQV---EACINIGLQCVEIDQ 258 R Y+ KE W E I EY+ L + +++ EAC I C Sbjct: 538 GFDPTIGLMRNYVVSKKERPQWRDEIIKHEYMSLLKKVTEEMWDPEACARITAGC----- 592 Query: 257 KKRPSIETIVNMLNKLPVSEEVSHS 183 + + N + P S E HS Sbjct: 593 ----AFARVWNHIMSSPDSSEGYHS 613
>EPHA2_MOUSE (Q03145) Ephrin type-A receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2) Length = 977 Score = 33.1 bits (74), Expect = 0.54 Identities = 25/107 (23%), Positives = 51/107 (47%) Frame = -1 Query: 530 VGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKENWTLEK 351 + + APE + + ++ SD++S G+++ E+ T R Y + N + K Sbjct: 782 IRWTAPEAISYRKFTSASDVWSYGIVMWEVMTYG----------ERPYWE--LSNHEVMK 829 Query: 350 IMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNKL 210 +++ L D A + +QC + ++ +RP IV++L+KL Sbjct: 830 AINDGFRLPT-PMDCPSAIYQLMMQCWQQERSRRPKFADIVSILDKL 875
>LIMK1_RAT (P53669) LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1)| Length = 647 Score = 32.7 bits (73), Expect = 0.70 Identities = 26/113 (23%), Positives = 51/113 (45%), Gaps = 1/113 (0%) Frame = -1 Query: 545 SVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYID-GVKE 369 +VVG+ +MAPE + + D++S G+++ EI R + D + + +D G+ Sbjct: 508 TVVGNPYWMAPEMINGRSYDEKVDVFSFGIVLCEIIGRV----NADPDYLPRTMDFGLNV 563 Query: 368 NWTLEKIMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNKL 210 L++ + + I ++C ++D +KRPS + L L Sbjct: 564 RGFLDRYCPP---------NCPPSFFPITVRCCDLDPEKRPSFVKLEQWLETL 607
>LIMK1_MOUSE (P53668) LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1) (KIZ-1)| Length = 647 Score = 32.7 bits (73), Expect = 0.70 Identities = 26/113 (23%), Positives = 51/113 (45%), Gaps = 1/113 (0%) Frame = -1 Query: 545 SVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYID-GVKE 369 +VVG+ +MAPE + + D++S G+++ EI R + D + + +D G+ Sbjct: 508 TVVGNPYWMAPEMINGRSYDEKVDVFSFGIVLCEIIGRV----NADPDYLPRTMDFGLNV 563 Query: 368 NWTLEKIMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNKL 210 L++ + + I ++C ++D +KRPS + L L Sbjct: 564 RGFLDRYCPP---------NCPPSFFPITVRCCDLDPEKRPSFVKLEQWLETL 607
>E2AK2_HUMAN (P19525) Interferon-induced, double-stranded RNA-activated protein| kinase (EC 2.7.11.1) (Interferon-inducible RNA-dependent protein kinase) (Protein kinase RNA-activated) (PKR) (p68 kinase) (P1/eIF-2A protein kinase) Length = 551 Score = 32.7 bits (73), Expect = 0.70 Identities = 20/73 (27%), Positives = 38/73 (52%), Gaps = 7/73 (9%) Frame = -1 Query: 536 GSVGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGV------ 375 G++ YM+PE + + + D+Y+LGLI+ E+ +++ K DG+ Sbjct: 450 GTLRYMSPEQISSQDYGKEVDLYALGLILAEL-LHVCDTAFETSKFFTDLRDGIISDIFD 508 Query: 374 -KENWTLEKIMSE 339 KE L+K++S+ Sbjct: 509 KKEKTLLQKLLSK 521
>ACV1C_MOUSE (Q8K348) Activin receptor type 1C precursor (EC 2.7.11.30)| (ACTR-IC) (Activin receptor-like kinase 7) (ALK-7) Length = 493 Score = 32.7 bits (73), Expect = 0.70 Identities = 23/70 (32%), Positives = 38/70 (54%), Gaps = 6/70 (8%) Frame = -1 Query: 539 VGSVGYMAPEYLYNG------EISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDG 378 VG+ YMAPE L + E R+DIYS+GL+ EI+ R + +++ Y D Sbjct: 363 VGTKRYMAPEMLDDTMNLSIFESFKRADIYSVGLVYWEIA-RRCSVGGVVEEYQLPYYDM 421 Query: 377 VKENWTLEKI 348 V + ++E++ Sbjct: 422 VPSDPSIEEM 431
>KS6A_CAEEL (Q21734) Putative ribosomal protein S6 kinase alpha (EC 2.7.11.1)| Length = 784 Score = 32.7 bits (73), Expect = 0.70 Identities = 17/49 (34%), Positives = 27/49 (55%) Frame = -1 Query: 551 TRSVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQ 405 T S G+V YMAPE + S +D +SLG+++ E+ T + D+ Sbjct: 261 TYSFCGTVEYMAPEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDR 309
>EPHA4_MOUSE (Q03137) Ephrin type-A receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor SEK) (MPK-3) Length = 986 Score = 32.7 bits (73), Expect = 0.70 Identities = 26/107 (24%), Positives = 50/107 (46%) Frame = -1 Query: 530 VGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKENWTLEK 351 + + APE + + ++ SD++S G+++ E+ + D + + I ++E + L Sbjct: 788 IRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYG-ERPYWDMSN-QDVIKAIEEGYRLPP 845 Query: 350 IMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNKL 210 M I L + + L C + ++ RP IVNML+KL Sbjct: 846 PMDCPIALHQ-----------LMLDCWQKERSDRPKFGQIVNMLDKL 881
>EPHA4_HUMAN (P54764) Ephrin type-A receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8) Length = 986 Score = 32.7 bits (73), Expect = 0.70 Identities = 26/107 (24%), Positives = 50/107 (46%) Frame = -1 Query: 530 VGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKENWTLEK 351 + + APE + + ++ SD++S G+++ E+ + D + + I ++E + L Sbjct: 788 IRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYG-ERPYWDMSN-QDVIKAIEEGYRLPP 845 Query: 350 IMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNKL 210 M I L + + L C + ++ RP IVNML+KL Sbjct: 846 PMDCPIALHQ-----------LMLDCWQKERSDRPKFGQIVNMLDKL 881
>EPHA4_CHICK (Q07496) Ephrin type-A receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor CEK8) Length = 986 Score = 32.7 bits (73), Expect = 0.70 Identities = 26/107 (24%), Positives = 50/107 (46%) Frame = -1 Query: 530 VGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKENWTLEK 351 + + APE + + ++ SD++S G+++ E+ + D + + I ++E + L Sbjct: 788 IRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYG-ERPYWDMSN-QDVIKAIEEGYRLPP 845 Query: 350 IMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNKL 210 M I L + + L C + ++ RP IVNML+KL Sbjct: 846 PMDCPIALHQ-----------LMLDCWQKERSDRPKFGQIVNMLDKL 881
>SPKD_SYNY3 (P54735) Serine/threonine-protein kinase D (EC 2.7.11.1)| Length = 505 Score = 32.7 bits (73), Expect = 0.70 Identities = 23/78 (29%), Positives = 43/78 (55%), Gaps = 5/78 (6%) Frame = -1 Query: 542 VVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXM-----NSSSTDQKHARKYIDG 378 V+G+ G+MAPE +G +D+Y+LGL I+ T+ + + T Q + ++ Sbjct: 178 VIGTRGFMAPEQ-SSGRSVFSTDLYALGLTIIYTLTKKLPVEFSSDQQTGQLDWQSHVS- 235 Query: 377 VKENWTLEKIMSEYIELE 324 K + L K++++ IE+E Sbjct: 236 -KIDSVLAKVINKAIEME 252
>SHK2_SCHPO (Q10056) Serine/threonine-protein kinase shk2 (EC 2.7.11.1)| Length = 589 Score = 32.7 bits (73), Expect = 0.70 Identities = 14/35 (40%), Positives = 25/35 (71%) Frame = -1 Query: 545 SVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEI 441 ++VG+ +MAPE + E + DI+SLG++I+E+ Sbjct: 468 TMVGTPYWMAPEVVKQNEYGTKVDIWSLGIMIIEM 502
>PKNJ_MYCTU (P65732) Probable serine/threonine-protein kinase pknJ (EC| 2.7.11.1) Length = 589 Score = 32.7 bits (73), Expect = 0.70 Identities = 15/39 (38%), Positives = 22/39 (56%) Frame = -1 Query: 551 TRSVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEIST 435 T SV+ ++ Y APE L R+D+YSLG + + T Sbjct: 173 TGSVLATLAYAAPEVLAGQGFDGRADLYSLGCALFRLLT 211
>PKNJ_MYCBO (P65733) Probable serine/threonine-protein kinase pknJ (EC| 2.7.11.1) Length = 589 Score = 32.7 bits (73), Expect = 0.70 Identities = 15/39 (38%), Positives = 22/39 (56%) Frame = -1 Query: 551 TRSVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEIST 435 T SV+ ++ Y APE L R+D+YSLG + + T Sbjct: 173 TGSVLATLAYAAPEVLAGQGFDGRADLYSLGCALFRLLT 211
>MERTK_HUMAN (Q12866) Proto-oncogene tyrosine-protein kinase MER precursor (EC| 2.7.10.1) (C-mer) (Receptor tyrosine kinase MerTK) Length = 999 Score = 32.7 bits (73), Expect = 0.70 Identities = 29/111 (26%), Positives = 46/111 (41%), Gaps = 4/111 (3%) Frame = -1 Query: 530 VGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKENWTLEK 351 V ++A E L + +++SD+++ G+ + EI TR M Q H Sbjct: 764 VKWIAIESLADRVYTSKSDVWAFGVTMWEIRTRGMTPYPGVQNHE--------------- 808 Query: 350 IMSEYIELEEHAFDQVEACIN----IGLQCVEIDQKKRPSIETIVNMLNKL 210 M +Y+ L H Q E C++ I C D RP+ + L KL Sbjct: 809 -MYDYL-LHGHRLKQPEDCLDELYEIMYSCWRTDPLDRPTFSVLRLQLEKL 857
>ACV1B_MOUSE (Q61271) Activin receptor type 1B precursor (EC 2.7.11.30)| (ACTR-IB) (Serine/threonine-protein kinase receptor R2) (SKR2) Length = 505 Score = 32.7 bits (73), Expect = 0.70 Identities = 24/71 (33%), Positives = 39/71 (54%), Gaps = 7/71 (9%) Frame = -1 Query: 539 VGSVGYMAPEYLYNGEISAR-------SDIYSLGLIIMEISTRXMNSSSTDQKHARKYID 381 VG+ YMAPE L + I+ + +DIY+LGL+ EI+ R NS + + Y D Sbjct: 375 VGTKRYMAPEVL-DETINMKHFDSFKCADIYALGLVYWEIA-RRCNSGGVHEDYQLPYYD 432 Query: 380 GVKENWTLEKI 348 V + ++E++ Sbjct: 433 LVPSDPSIEEM 443
>PKNF_MYCTU (P72003) Probable serine/threonine-protein kinase pknF (EC| 2.7.11.1) Length = 476 Score = 32.7 bits (73), Expect = 0.70 Identities = 15/39 (38%), Positives = 20/39 (51%) Frame = -1 Query: 551 TRSVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEIST 435 T VG+V Y APE L E+ R+D Y+L + T Sbjct: 175 TNMTVGTVSYAAPEQLMGNELDGRADQYALAATAFHLLT 213
>PKNF_MYCBO (Q7TZN1) Probable serine/threonine-protein kinase pknF (EC| 2.7.11.1) Length = 476 Score = 32.7 bits (73), Expect = 0.70 Identities = 15/39 (38%), Positives = 20/39 (51%) Frame = -1 Query: 551 TRSVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEIST 435 T VG+V Y APE L E+ R+D Y+L + T Sbjct: 175 TNMTVGTVSYAAPEQLMGNELDGRADQYALAATAFHLLT 213
>PKNA_MYCLE (P54743) Probable serine/threonine-protein kinase pknA (EC| 2.7.11.1) Length = 437 Score = 32.7 bits (73), Expect = 0.70 Identities = 15/37 (40%), Positives = 23/37 (62%) Frame = -1 Query: 551 TRSVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEI 441 T V+G+ Y+APE + + SD+YSLG+I E+ Sbjct: 174 TGMVMGTAQYIAPEQALGHDATPASDVYSLGVIGYEV 210
>MIPR_LYMST (Q25410) Putative molluscan insulin-related peptide(s) receptor| precursor (EC 2.7.10.1) [Contains: Putative molluscan insulin-related peptide(s) receptor alpha chain; Putative molluscan insulin-related peptide(s) receptor beta chain] Length = 1607 Score = 32.7 bits (73), Expect = 0.70 Identities = 32/118 (27%), Positives = 58/118 (49%), Gaps = 3/118 (2%) Frame = -1 Query: 530 VGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKENWTLEK 351 V +MAPE L +G ++ SD++S G+++ E+ T A + G+ ++ Sbjct: 1214 VRWMAPESLKDGVFTSLSDVWSYGVVMWEMVTL-----------AAQPYQGLSNEEVVKF 1262 Query: 350 IMSEYI-ELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVN-MLNKL-PVSEEVSH 186 I YI EL E+ +++ + C +RP+ + I+ +L KL P E+VS+ Sbjct: 1263 ISDGYIMELPENCPNEMAYLMQ---HCWAKKPNQRPTFKAIIEYLLPKLKPSFEKVSY 1317
>PGFRA_MOUSE (P26618) Alpha platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-alpha) Length = 1089 Score = 32.7 bits (73), Expect = 0.70 Identities = 29/109 (26%), Positives = 51/109 (46%), Gaps = 5/109 (4%) Frame = -1 Query: 530 VGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKENWTLEK 351 V +MAPE +++ + SD++S G+++ EI + Y + ++ K Sbjct: 859 VKWMAPESIFDNLYTTLSDVWSYGILLWEIFSLG----------GTPYPGMMVDSTFYNK 908 Query: 350 IMSEY-IELEEHAFDQVEACINIGLQCVEIDQKKRPSI----ETIVNML 219 I S Y + +HA +V I +QC + +KRPS E + N+L Sbjct: 909 IKSGYRMAKPDHATSEV---YEIMVQCWNSEPEKRPSFYHLSEIVENLL 954
>LIN2_CAEEL (P54936) Protein lin-2 (Abnormal cell lineage protein 2)| Length = 961 Score = 32.7 bits (73), Expect = 0.70 Identities = 26/106 (24%), Positives = 50/106 (47%), Gaps = 1/106 (0%) Frame = -1 Query: 539 VGSVGYMAPEYLYNGEISARSDIYSLGLII-MEISTRXMNSSSTDQKHARKYIDGVKENW 363 VG +MAPE + +S SDI+S G+++ + ++ R S ST + Sbjct: 186 VGVPQFMAPEIVRKDRVSCSSDIWSSGVVLFLLLAGRLPFSGSTSDIY------------ 233 Query: 362 TLEKIMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVN 225 E+IM ++++ + + E+ N+ + + D KR S + +N Sbjct: 234 --ERIMQTDVDVDGYMPNISESARNLVRRMLNADPSKRISAKEALN 277
>KIN3_YEAST (P22209) Serine/threonine-protein kinase KIN3 (EC 2.7.11.1)| Length = 435 Score = 32.7 bits (73), Expect = 0.70 Identities = 16/33 (48%), Positives = 22/33 (66%) Frame = -1 Query: 539 VGSVGYMAPEYLYNGEISARSDIYSLGLIIMEI 441 VG+ YM+PE L + S SDI+SLG +I E+ Sbjct: 249 VGTPYYMSPEVLMDQPYSPLSDIWSLGCVIFEM 281
>CHK1_YEAST (P38147) Serine/threonine-protein kinase CHK1 (EC 2.7.11.1)| (Checkpoint kinase 1) Length = 527 Score = 32.7 bits (73), Expect = 0.70 Identities = 16/36 (44%), Positives = 25/36 (69%), Gaps = 2/36 (5%) Frame = -1 Query: 536 GSVGYMAPEYLYN--GEISARSDIYSLGLIIMEIST 435 GS YMAPE LY+ G + R+DI+S+G+++ + T Sbjct: 182 GSPPYMAPEVLYSEEGYYADRTDIWSIGILLFVLLT 217
>PGFRB_MOUSE (P05622) Beta platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-beta) Length = 1098 Score = 32.7 bits (73), Expect = 0.70 Identities = 24/105 (22%), Positives = 49/105 (46%) Frame = -1 Query: 524 YMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKENWTLEKIM 345 +MAPE ++N + SD++S G+++ EI T + + ++ + +K + + + Sbjct: 868 WMAPESIFNSLYTTLSDVWSFGILLWEIFTLG-GTPYPELPMNDQFYNAIKRGYRMAQ-- 924 Query: 344 SEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNKL 210 HA D++ I +C E + RP +V +L +L Sbjct: 925 ------PAHASDEI---YEIMQKCWEEKFETRPPFSQLVLLLERL 960
>PGFRB_CANFA (Q6QNF3) Beta platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-beta) Length = 1103 Score = 32.7 bits (73), Expect = 0.70 Identities = 24/105 (22%), Positives = 49/105 (46%) Frame = -1 Query: 524 YMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKENWTLEKIM 345 +MAPE ++N + SD++S G+++ EI T + + ++ + +K + + + Sbjct: 869 WMAPESIFNSLYTTLSDVWSFGILLWEIFTLG-GTPYPELPMNEQFYNAIKRGYRMAQ-- 925 Query: 344 SEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNKL 210 HA D++ I +C E + RP +V +L +L Sbjct: 926 ------PAHASDEI---YEIMQKCWEEKFEIRPPFSQLVLLLERL 961
>7LESS_DROVI (P20806) Protein sevenless (EC 2.7.10.1)| Length = 2594 Score = 32.7 bits (73), Expect = 0.70 Identities = 31/129 (24%), Positives = 57/129 (44%) Frame = -1 Query: 530 VGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKENWTLEK 351 V +MA E L +G S +SD+++ G++ EI T + ++ + + VKE L++ Sbjct: 2402 VRWMALESLVDGLFSTQSDVWAFGVLCWEIFT--LGQQPYAARNNFEVLAHVKEGGRLQQ 2459 Query: 350 IMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNKLPVSEEVSHSM*AQ 171 E +++ A + LQC + +RPS + ++ L L + + Sbjct: 2460 --------PERCPEKLYALL---LQCWRSEPWERPSFKRCLSTLQALSSDLRRTEMLATD 2508 Query: 170 NFPLFSERC 144 PL S C Sbjct: 2509 ETPLVSALC 2517
>PGFRB_RAT (Q05030) Beta platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-beta) Length = 1097 Score = 32.7 bits (73), Expect = 0.70 Identities = 24/105 (22%), Positives = 49/105 (46%) Frame = -1 Query: 524 YMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKENWTLEKIM 345 +MAPE ++N + SD++S G+++ EI T + + ++ + +K + + + Sbjct: 868 WMAPESIFNSLYTTLSDVWSFGILLWEIFTLG-GTPYPELPMNDQFYNAIKRGYRMAQ-- 924 Query: 344 SEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNKL 210 HA D++ I +C E + RP +V +L +L Sbjct: 925 ------PAHASDEI---YEIMQKCWEEKFETRPPFSQLVLLLERL 960
>KPCD2_HUMAN (Q9BZL6) Serine/threonine-protein kinase D2 (EC 2.7.11.13)| (nPKC-D2) Length = 878 Score = 32.7 bits (73), Expect = 0.70 Identities = 15/33 (45%), Positives = 23/33 (69%) Frame = -1 Query: 548 RSVVGSVGYMAPEYLYNGEISARSDIYSLGLII 450 RSVVG+ Y+APE L N + D++S+G+I+ Sbjct: 709 RSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIM 741
>PGFRB_HUMAN (P09619) Beta platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-beta) (CD140b antigen) Length = 1106 Score = 32.7 bits (73), Expect = 0.70 Identities = 24/105 (22%), Positives = 49/105 (46%) Frame = -1 Query: 524 YMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKENWTLEKIM 345 +MAPE ++N + SD++S G+++ EI T + + ++ + +K + + + Sbjct: 869 WMAPESIFNSLYTTLSDVWSFGILLWEIFTLG-GTPYPELPMNEQFYNAIKRGYRMAQ-- 925 Query: 344 SEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNKL 210 HA D++ I +C E + RP +V +L +L Sbjct: 926 ------PAHASDEI---YEIMQKCWEEKFEIRPPFSQLVLLLERL 961
>ZYG1_CAEEL (Q9GT24) Probable serine/threonine-protein kinase zyg-1 (EC| 2.7.11.1) (Zygote defective protein 1) Length = 706 Score = 32.7 bits (73), Expect = 0.70 Identities = 14/39 (35%), Positives = 28/39 (71%) Frame = -1 Query: 551 TRSVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEIST 435 T ++VG+ G++AP+ +Y+ E + +D+YSLG ++ + T Sbjct: 166 TCTIVGTPGFIAPQ-VYDQEYTQSADVYSLGAVLYTMLT 203
>HCK_MOUSE (P08103) Tyrosine-protein kinase HCK (EC 2.7.10.2)| (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK) Length = 523 Score = 32.7 bits (73), Expect = 0.70 Identities = 28/118 (23%), Positives = 52/118 (44%), Gaps = 6/118 (5%) Frame = -1 Query: 530 VGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKENWTLEK 351 + + APE + G + +SD++S G+++MEI T + R G+ Sbjct: 418 IKWTAPEAINFGSFTIKSDVWSFGILLMEIVT-----------YGRIPYPGMSN------ 460 Query: 350 IMSEYIELEEHAF------DQVEACINIGLQCVEIDQKKRPSIETIVNMLNKLPVSEE 195 E I EH + + E NI ++C + ++RP+ E I ++L+ + E Sbjct: 461 --PEVIRALEHGYRMPRPDNCPEELYNIMIRCWKNRPEERPTFEYIQSVLDDFYTATE 516
>CDS1_SCHPO (Q09170) Serine/threonine-protein kinase cds1 (EC 2.7.11.1)| (Checkpoint kinase cds1) Length = 460 Score = 32.3 bits (72), Expect = 0.92 Identities = 23/90 (25%), Positives = 43/90 (47%), Gaps = 6/90 (6%) Frame = -1 Query: 536 GSVGYMAPEYL------YNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGV 375 G++GY+APE L +G + DI+SLG ++ + T + +S+ Q + I Sbjct: 331 GTMGYLAPEVLKSKNVNLDGGYDDKVDIWSLGCVLYVMLTASIPFASSSQAKCIELIS-- 388 Query: 374 KENWTLEKIMSEYIELEEHAFDQVEACINI 285 K + +E ++ E+ E D + + I Sbjct: 389 KGAYPIEPLLEN--EISEEGIDLINRMLEI 416
>ACV1C_RAT (P70539) Activin receptor type 1C precursor (EC 2.7.11.30)| (ACTR-IC) (Activin receptor-like kinase 7) (ALK-7) Length = 493 Score = 32.3 bits (72), Expect = 0.92 Identities = 23/70 (32%), Positives = 38/70 (54%), Gaps = 6/70 (8%) Frame = -1 Query: 539 VGSVGYMAPEYLYNG------EISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDG 378 VG+ YMAPE L + E R+DIYS+GL+ EI+ R + +++ Y D Sbjct: 363 VGTKRYMAPEMLDDTMNVNIFESFKRADIYSVGLVYWEIA-RRCSVGGLVEEYQLPYYDM 421 Query: 377 VKENWTLEKI 348 V + ++E++ Sbjct: 422 VPSDPSIEEM 431
>ACV1C_HUMAN (Q8NER5) Activin receptor type 1C precursor (EC 2.7.11.30)| (ACTR-IC) (Activin receptor-like kinase 7) (ALK-7) Length = 493 Score = 32.3 bits (72), Expect = 0.92 Identities = 23/70 (32%), Positives = 38/70 (54%), Gaps = 6/70 (8%) Frame = -1 Query: 539 VGSVGYMAPEYLYNG------EISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDG 378 VG+ YMAPE L + E R+DIYS+GL+ EI+ R + +++ Y D Sbjct: 363 VGTKRYMAPEMLDDTMNVNIFESFKRADIYSVGLVYWEIA-RRCSVGGIVEEYQLPYYDM 421 Query: 377 VKENWTLEKI 348 V + ++E++ Sbjct: 422 VPSDPSIEEM 431
>STE11_YEAST (P23561) Serine/threonine-protein kinase STE11 (EC 2.7.11.1)| Length = 738 Score = 32.3 bits (72), Expect = 0.92 Identities = 14/37 (37%), Positives = 26/37 (70%) Frame = -1 Query: 545 SVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEIST 435 S+ GSV +M+PE + +A++DI+S G +++E+ T Sbjct: 637 SLQGSVFWMSPEVVKQTATTAKADIWSTGCVVIEMFT 673
>SRMS_HUMAN (Q9H3Y6) Tyrosine-protein kinase Srms (EC 2.7.10.2)| Length = 488 Score = 32.3 bits (72), Expect = 0.92 Identities = 27/107 (25%), Positives = 50/107 (46%) Frame = -1 Query: 530 VGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKENWTLEK 351 V + APE S +SD++S G+++ E+ T + + +G+ + TL++ Sbjct: 390 VKWTAPEAANYRVFSQKSDVWSFGVLLHEVFT-----------YGQCPYEGMTNHETLQQ 438 Query: 350 IMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNKL 210 IM Y L A E + + L+C ++RPS T+ L+ + Sbjct: 439 IMRGY-RLPRPAACPAEVYV-LMLECWRSSPEERPSFATLREKLHAI 483
>GRK4_MOUSE (O70291) G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK4) Length = 574 Score = 32.3 bits (72), Expect = 0.92 Identities = 27/122 (22%), Positives = 55/122 (45%) Frame = -1 Query: 548 RSVVGSVGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKE 369 R VG+VGYMAPE + + + + D + LG +I E+ RKY + V Sbjct: 343 RGRVGTVGYMAPEIINHEKYTFSPDWWGLGCLIYEM--------IAGHSPFRKYKEKVNR 394 Query: 368 NWTLEKIMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNKLPVSEEVS 189 ++ +E E E + ++ ++ L ++ K+ V+ + + P+ ++++ Sbjct: 395 EELERRVKNETEEYSERFSEDAKSICSMLL--IKDPSKRLGCQRDGVSAVKQHPIFKDIN 452 Query: 188 HS 183 S Sbjct: 453 FS 454
>EPHA7_MOUSE (Q61772) Ephrin type-A receptor 7 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Embryonic brain kinase) (EBK) (Developmental kinase 1) (MDK-1) Length = 998 Score = 32.3 bits (72), Expect = 0.92 Identities = 27/107 (25%), Positives = 48/107 (44%) Frame = -1 Query: 530 VGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKENWTLEK 351 V + APE + + ++ SD++S G+++ E+ + R Y D N + K Sbjct: 800 VRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYG----------ERPYWD--MSNQDVIK 847 Query: 350 IMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNKL 210 + E L D + L C + D+ +RP E IV +L+K+ Sbjct: 848 AIEEGYRLPA-PMDCPAGLHQLMLDCWQKDRAERPKFEQIVGILDKM 893
>EPHA3_RAT (O08680) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor REK4) (TYRO-4) Length = 984 Score = 32.3 bits (72), Expect = 0.92 Identities = 26/107 (24%), Positives = 47/107 (43%) Frame = -1 Query: 530 VGYMAPEYLYNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKYIDGVKENWTLEK 351 V + +PE + ++ SD++S G+++ E+ + + + I V E + L Sbjct: 789 VRWTSPEATAYRKFTSASDVWSYGIVLWEVMS--YGERPYWEMSNQDVIKAVDEGYRLPL 846 Query: 350 IMSEYIELEEHAFDQVEACINIGLQCVEIDQKKRPSIETIVNMLNKL 210 M D A + L C + D+ RP E IV++L+KL Sbjct: 847 PM-----------DCPAALYQLMLDCWQKDRNNRPKFEQIVSILDKL 882
>AVR2A_RAT (P38444) Activin receptor type 2A precursor (EC 2.7.11.30) (Activin| receptor type IIA) (ACTR-IIA) Length = 513 Score = 32.3 bits (72), Expect = 0.92 Identities = 18/71 (25%), Positives = 38/71 (53%), Gaps = 5/71 (7%) Frame = -1 Query: 551 TRSVVGSVGYMAPEYL-----YNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKY 387 T VG+ YMAPE L + + R D+Y++GL++ E+++R + ++ + Sbjct: 356 THGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELASRCTAADGPVDEYMLPF 415 Query: 386 IDGVKENWTLE 354 + + ++ +LE Sbjct: 416 EEEIGQHPSLE 426
>AVR2A_MOUSE (P27038) Activin receptor type 2A precursor (EC 2.7.11.30) (Activin| receptor type IIA) (ACTR-IIA) Length = 513 Score = 32.3 bits (72), Expect = 0.92 Identities = 18/71 (25%), Positives = 38/71 (53%), Gaps = 5/71 (7%) Frame = -1 Query: 551 TRSVVGSVGYMAPEYL-----YNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKY 387 T VG+ YMAPE L + + R D+Y++GL++ E+++R + ++ + Sbjct: 356 THGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELASRCTAADGPVDEYMLPF 415 Query: 386 IDGVKENWTLE 354 + + ++ +LE Sbjct: 416 EEEIGQHPSLE 426
>AVR2A_HUMAN (P27037) Activin receptor type 2A precursor (EC 2.7.11.30) (Activin| receptor type IIA) (ACTR-IIA) (ACTRIIA) Length = 513 Score = 32.3 bits (72), Expect = 0.92 Identities = 18/71 (25%), Positives = 38/71 (53%), Gaps = 5/71 (7%) Frame = -1 Query: 551 TRSVVGSVGYMAPEYL-----YNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKY 387 T VG+ YMAPE L + + R D+Y++GL++ E+++R + ++ + Sbjct: 356 THGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELASRCTAADGPVDEYMLPF 415 Query: 386 IDGVKENWTLE 354 + + ++ +LE Sbjct: 416 EEEIGQHPSLE 426
>AVR2A_BOVIN (Q28043) Activin receptor type 2A precursor (EC 2.7.11.30) (Activin| receptor type IIA) (ACTR-IIA) Length = 513 Score = 32.3 bits (72), Expect = 0.92 Identities = 18/71 (25%), Positives = 38/71 (53%), Gaps = 5/71 (7%) Frame = -1 Query: 551 TRSVVGSVGYMAPEYL-----YNGEISARSDIYSLGLIIMEISTRXMNSSSTDQKHARKY 387 T VG+ YMAPE L + + R D+Y++GL++ E+++R + ++ + Sbjct: 356 THGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELASRCTAADGPVDEYMLPF 415 Query: 386 IDGVKENWTLE 354 + + ++ +LE Sbjct: 416 EEEIGQHPSLE 426
>PKNA_MYCTU (P65726) Probable serine/threonine-protein kinase pknA (EC| 2.7.11.1) Length = 431 Score = 32.3 bits (72), Expect = 0.92 Identities = 14/33 (42%), Positives = 21/33 (63%) Frame = -1 Query: 551 TRSVVGSVGYMAPEYLYNGEISARSDIYSLGLI 453 T V+G+ Y+APE + S SD+YSLG++ Sbjct: 174 TGMVMGTAQYIAPEQALGHDASPASDVYSLGVV 206 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 78,981,536 Number of Sequences: 219361 Number of extensions: 1536173 Number of successful extensions: 4588 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 4369 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4520 length of database: 80,573,946 effective HSP length: 105 effective length of database: 57,541,041 effective search space used: 4488201198 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
