>CUL1_ARATH (Q94AH6) Cullin-1|
          Length = 738

 Score =  216 bits (551), Expect = 4e-56
 Identities = 110/146 (75%), Positives = 122/146 (83%)
 Frame = -2

Query: 664  EIVTQLNLSDDDVVRLLHSLSCAKYKILSKEPAGRTISPNDSFEFNSKFTDRMRRIKIPL 485
            EI+ QLNLS +D+VRLLHSLSCAKYKIL KEP  +T+S ND+FEFNSKFTDRMRRIKIPL
Sbjct: 593  EILAQLNLSHEDLVRLLHSLSCAKYKILLKEPNTKTVSQNDAFEFNSKFTDRMRRIKIPL 652

Query: 484  PPXXXXXXXXXXXXXDRRYAIDASIVRIMKSRKVMAHTQLVAECVEQLSRMFKPDFKAIK 305
            PP             DRRYAIDA+IVRIMKSRKV+ H QLV+ECVEQLSRMFKPD KAIK
Sbjct: 653  PPVDERKKVVEDVDKDRRYAIDAAIVRIMKSRKVLGHQQLVSECVEQLSRMFKPDIKAIK 712

Query: 304  KRIEDLITRDYLERDKDNANTYRYLA 227
            KR+EDLITRDYLERDK+N N +RYLA
Sbjct: 713  KRMEDLITRDYLERDKENPNMFRYLA 738

>CUL3_SCHPO (Q09760) Cullin-3 (Cul-3)|
          Length = 785

 Score =  117 bits (292), Expect = 4e-26
 Identities = 65/152 (42%), Positives = 83/152 (54%), Gaps = 6/152 (3%)
 Frame = -2

Query: 664  EIVTQLNLSDDDVVRLLHSLSCAKYKILSKEPAGRTISPNDSFEFNSKFTDRMRRIKIP- 488
            EI+ + N+   D+ R L SL+CAKYKIL K+P GR ++  D F FN  F   + RIKI  
Sbjct: 634  EILEKTNIEVGDLKRNLQSLACAKYKILLKDPKGREVNAGDKFYFNENFVSNLARIKIST 693

Query: 487  -----LPPXXXXXXXXXXXXXDRRYAIDASIVRIMKSRKVMAHTQLVAECVEQLSRMFKP 323
                 +                R++  DA IVR+MK RKV  H QL+AE   QL+  F P
Sbjct: 694  VAQTRVEDDSERKRTLEKVDESRKHQADACIVRVMKDRKVCEHNQLMAEVTRQLNPRFHP 753

Query: 322  DFKAIKKRIEDLITRDYLERDKDNANTYRYLA 227
                IK+RIE LI R+YL+R  DN   Y YLA
Sbjct: 754  SPMMIKRRIEALIEREYLQRQADNGRIYEYLA 785

>CUL4A_HUMAN (Q13619) Cullin-4A (CUL-4A)|
          Length = 659

 Score =  109 bits (272), Expect = 8e-24
 Identities = 64/150 (42%), Positives = 82/150 (54%), Gaps = 4/150 (2%)
 Frame = -2

Query: 664 EIVTQLNLSDDDVVRLLHSLSCAKYKILSKEPAGRTISPNDSFEFNSKFTDRMRRIKI-- 491
           EI     + D ++ R L SL+C K ++L K P G+ +   D F FN +F  ++ RIKI  
Sbjct: 512 EIKMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNGEFKHKLFRIKINQ 571

Query: 490 --PLPPXXXXXXXXXXXXXDRRYAIDASIVRIMKSRKVMAHTQLVAECVEQLSRMFKPDF 317
                              DR+Y IDA+IVRIMK RK + H  LV+E   QL    KP  
Sbjct: 572 IQMKETVEEQVSTTERVFQDRQYQIDAAIVRIMKMRKTLGHNLLVSELYNQLKFPVKPG- 630

Query: 316 KAIKKRIEDLITRDYLERDKDNANTYRYLA 227
             +KKRIE LI RDY+ERDKDN N Y Y+A
Sbjct: 631 -DLKKRIESLIDRDYMERDKDNPNQYHYVA 659

>CUL4B_HUMAN (Q13620) Cullin-4B (CUL-4B)|
          Length = 895

 Score =  106 bits (264), Expect = 7e-23
 Identities = 63/150 (42%), Positives = 82/150 (54%), Gaps = 4/150 (2%)
 Frame = -2

Query: 664  EIVTQLNLSDDDVVRLLHSLSCAKYKILSKEPAGRTISPNDSFEFNSKFTDRMRRIKIPL 485
            EI     + D ++ R L SL+C K ++L+K P G+ I   D F  N  F  ++ RIKI  
Sbjct: 748  EIKQATGIEDGELRRTLQSLACGKARVLAKNPKGKDIEDGDKFICNDDFKHKLFRIKINQ 807

Query: 484  ----PPXXXXXXXXXXXXXDRRYAIDASIVRIMKSRKVMAHTQLVAECVEQLSRMFKPDF 317
                               DR+Y IDA+IVRIMK RK ++H  LV+E   QL    KP  
Sbjct: 808  IQMKETVEEQASTTERVFQDRQYQIDAAIVRIMKMRKTLSHNLLVSEVYNQLKFPVKP-- 865

Query: 316  KAIKKRIEDLITRDYLERDKDNANTYRYLA 227
              +KKRIE LI RDY+ERDK+N N Y Y+A
Sbjct: 866  ADLKKRIESLIDRDYMERDKENPNQYNYIA 895

>CUL3_MOUSE (Q9JLV5) Cullin-3 (CUL-3)|
          Length = 768

 Score = 97.8 bits (242), Expect = 3e-20
 Identities = 59/154 (38%), Positives = 83/154 (53%), Gaps = 8/154 (5%)
 Frame = -2

Query: 664  EIVTQLNLSDDDVVRLLHSLSCAK--YKILSKEPAGRTISPNDSFEFNSKFTDRMRRIKI 491
            EI  + ++ + ++VR L SL+C K   ++L+KEP  + I     F  N +FT ++ R+KI
Sbjct: 615  EIQQETDIPERELVRALQSLACGKPTQRVLTKEPKSKEIESGHIFTVNDQFTSKLHRVKI 674

Query: 490  PLPPXXXXXX------XXXXXXXDRRYAIDASIVRIMKSRKVMAHTQLVAECVEQLSRMF 329
                                   DR++ I+A+IVRIMKSRK M H  LVAE  +QL   F
Sbjct: 675  QTVAAKQGESDPERKETRQKVDDDRKHEIEAAIVRIMKSRKKMQHNVLVAEVTQQLKARF 734

Query: 328  KPDFKAIKKRIEDLITRDYLERDKDNANTYRYLA 227
             P    IKKRIE LI R+YL R  ++   Y Y+A
Sbjct: 735  LPSPVVIKKRIEGLIEREYLARTPEDRKVYTYVA 768

>CUL3_HUMAN (Q13618) Cullin-3 (CUL-3)|
          Length = 768

 Score = 97.4 bits (241), Expect = 3e-20
 Identities = 59/154 (38%), Positives = 83/154 (53%), Gaps = 8/154 (5%)
 Frame = -2

Query: 664  EIVTQLNLSDDDVVRLLHSLSCAK--YKILSKEPAGRTISPNDSFEFNSKFTDRMRRIKI 491
            EI  + ++ + ++VR L SL+C K   ++L+KEP  + I     F  N +FT ++ R+KI
Sbjct: 615  EIQQETDIPERELVRALQSLACGKPTQRVLTKEPKSKEIENGHIFTVNDQFTSKLHRVKI 674

Query: 490  PLPPXXXXXX------XXXXXXXDRRYAIDASIVRIMKSRKVMAHTQLVAECVEQLSRMF 329
                                   DR++ I+A+IVRIMKSRK M H  LVAE  +QL   F
Sbjct: 675  QTVAAKQGESDPERKETRQKVDDDRKHEIEAAIVRIMKSRKKMQHNVLVAEVTQQLKARF 734

Query: 328  KPDFKAIKKRIEDLITRDYLERDKDNANTYRYLA 227
             P    IKKRIE LI R+YL R  ++   Y Y+A
Sbjct: 735  LPSPVVIKKRIEGLIEREYLARTPEDRKVYTYVA 768

>CUL3_CAEEL (Q17391) Cullin-3|
          Length = 777

 Score = 81.6 bits (200), Expect = 2e-15
 Identities = 51/154 (33%), Positives = 83/154 (53%), Gaps = 8/154 (5%)
 Frame = -2

Query: 664  EIVTQLNLSDDDVVRLLHSLSCAK--YKILSKEPAGR-TISPNDSFEFNSKFTDRMRRIK 494
            +++ +L + + ++ R L SL+  K   +IL ++  G+  I  +D F  N  F  ++ R+K
Sbjct: 624  QLMDELKIPERELKRNLQSLALGKASQRILVRKNKGKDAIDMSDEFAVNDNFQSKLTRVK 683

Query: 493  IPLPPXXXXXX-----XXXXXXXDRRYAIDASIVRIMKSRKVMAHTQLVAECVEQLSRMF 329
            + +                    DR+  ++A+IVRIMK+RK + H  LVAE  +QL   F
Sbjct: 684  VQMVTGKVESEPEIRETRQKVEDDRKLEVEAAIVRIMKARKKLNHNNLVAEVTQQLRHRF 743

Query: 328  KPDFKAIKKRIEDLITRDYLERDKDNANTYRYLA 227
             P    IK+RIE LI R+YL RD+ +   Y+Y+A
Sbjct: 744  MPSPIIIKQRIETLIEREYLARDEHDHRAYQYIA 777

>CUL4_SCHPO (O14122) Cullin-4 (Cul-4)|
          Length = 734

 Score = 78.2 bits (191), Expect = 2e-14
 Identities = 48/139 (34%), Positives = 71/139 (51%), Gaps = 4/139 (2%)
 Frame = -2

Query: 643  LSDDDVVRLLHSLSCAKYKILSKEPAGRTISPNDSFEFNSKFTDRMRRIKIP----LPPX 476
            LSD D+ R L SLSCA+ + L   P  +  SP+  F  N KFTD++ R+KI         
Sbjct: 594  LSDIDLTRTLQSLSCARIRPLVMVPKSKKPSPDTMFYVNEKFTDKLYRVKINQIYLKEER 653

Query: 475  XXXXXXXXXXXXDRRYAIDASIVRIMKSRKVMAHTQLVAECVEQLSRMFKPDFKAIKKRI 296
                        DR++ + ASIVR+MK ++ M H  LV   +  +     P    +K  I
Sbjct: 654  QENSDVQEQVVRDRQFELQASIVRVMKQKEKMKHDDLVQYVINNVKDRGIPLVSDVKTAI 713

Query: 295  EDLITRDYLERDKDNANTY 239
            E L+ ++YLER+ ++  TY
Sbjct: 714  EKLLEKEYLEREDNDIYTY 732

>CUL1_DROME (Q24311) Cullin homolog 1 (Lin-19 homolog protein)|
          Length = 774

 Score = 76.3 bits (186), Expect = 8e-14
 Identities = 48/140 (34%), Positives = 75/140 (53%), Gaps = 4/140 (2%)
 Frame = -2

Query: 634  DDVVRLLHSLSCAKYKILSKEPAGRTISPNDSFEFNSKFTDRMRRIKIPLPPXXXXXXXX 455
            ++++++L  L   K K+L+      +++P  + E    + ++ RRI I  P         
Sbjct: 637  ENLIQVLQIL--LKAKVLTSSDNENSLTPESTVELFLDYKNKKRRININQPLKTELKVEQ 694

Query: 454  XXXXXD----RRYAIDASIVRIMKSRKVMAHTQLVAECVEQLSRMFKPDFKAIKKRIEDL 287
                      R+  I A+IVRIMK RK + HT L++E + QLS  FKP    IKK I+ L
Sbjct: 695  ETVHKHIEEDRKLLIQAAIVRIMKMRKRLNHTNLISEVLNQLSTRFKPKVPVIKKCIDIL 754

Query: 286  ITRDYLERDKDNANTYRYLA 227
            I ++YLER + + +TY YLA
Sbjct: 755  IEKEYLERMEGHKDTYSYLA 774

>CUL4_CAEEL (Q17392) Cullin-4|
          Length = 840

 Score = 73.2 bits (178), Expect = 7e-13
 Identities = 43/111 (38%), Positives = 63/111 (56%), Gaps = 4/111 (3%)
 Frame = -2

Query: 547  NDSFEFNSKFTDRMRRIKIPLPPXXXXXXXXXXXX----XDRRYAIDASIVRIMKSRKVM 380
            N+ F  NSKFT++  R++I                     DR+Y IDA++VRIMK+RK +
Sbjct: 732  NEKFVVNSKFTEKRCRVRIAQVNIKTAVEETKEVKEEVNSDRQYKIDAAVVRIMKARKQL 791

Query: 379  AHTQLVAECVEQLSRMFKPDFKAIKKRIEDLITRDYLERDKDNANTYRYLA 227
             H  L+ E ++QL   F      IKKR+E LI R+Y+ RD + A++Y Y+A
Sbjct: 792  NHQTLMTELLQQL--RFPVSTADIKKRLESLIEREYISRDPEEASSYNYVA 840

>CUL1_PONPY (Q5R4G6) Cullin-1 (CUL-1)|
          Length = 776

 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 37/70 (52%), Positives = 46/70 (65%)
 Frame = -2

Query: 436 RRYAIDASIVRIMKSRKVMAHTQLVAECVEQLSRMFKPDFKAIKKRIEDLITRDYLERDK 257
           R+  I A+IVRIMK RKV+ H QL+ E + QLS  FKP    IKK I+ LI ++YLER  
Sbjct: 707 RKLLIQAAIVRIMKMRKVLKHQQLLGEVLTQLSSRFKPRVPVIKKCIDILIEKEYLERVD 766

Query: 256 DNANTYRYLA 227
              +TY YLA
Sbjct: 767 GEKDTYSYLA 776

>CUL1_MOUSE (Q9WTX6) Cullin-1 (CUL-1)|
          Length = 776

 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 37/70 (52%), Positives = 46/70 (65%)
 Frame = -2

Query: 436 RRYAIDASIVRIMKSRKVMAHTQLVAECVEQLSRMFKPDFKAIKKRIEDLITRDYLERDK 257
           R+  I A+IVRIMK RKV+ H QL+ E + QLS  FKP    IKK I+ LI ++YLER  
Sbjct: 707 RKLLIQAAIVRIMKMRKVLKHQQLLGEVLTQLSSRFKPRVPVIKKCIDILIEKEYLERVD 766

Query: 256 DNANTYRYLA 227
              +TY YLA
Sbjct: 767 GEKDTYSYLA 776

>CUL1_HUMAN (Q13616) Cullin-1 (CUL-1)|
          Length = 776

 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 37/70 (52%), Positives = 46/70 (65%)
 Frame = -2

Query: 436 RRYAIDASIVRIMKSRKVMAHTQLVAECVEQLSRMFKPDFKAIKKRIEDLITRDYLERDK 257
           R+  I A+IVRIMK RKV+ H QL+ E + QLS  FKP    IKK I+ LI ++YLER  
Sbjct: 707 RKLLIQAAIVRIMKMRKVLKHQQLLGEVLTQLSSRFKPRVPVIKKCIDILIEKEYLERVD 766

Query: 256 DNANTYRYLA 227
              +TY YLA
Sbjct: 767 GEKDTYSYLA 776

>CUL2_PONPY (Q5RCF3) Cullin-2 (CUL-2)|
          Length = 745

 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 43/150 (28%), Positives = 71/150 (47%), Gaps = 4/150 (2%)
 Frame = -2

Query: 664  EIVTQLNLSDDDVVRLLHSLSCAKYKILSKEPAGRTISPNDSFEFNSKFTDRMRRIKIPL 485
            E+     +++ ++ + + SL     K+++ +     I    SF  N  F+ +  + KI  
Sbjct: 598  ELQDSTQMNEKELTKTIKSL--LDVKMINHDSEKEDIDAESSFSLNMNFSSKRTKFKITT 655

Query: 484  PPXXXX----XXXXXXXXXDRRYAIDASIVRIMKSRKVMAHTQLVAECVEQLSRMFKPDF 317
                               DR+  + A+IVRIMK+RKV+ H  L+ E + Q    F P  
Sbjct: 656  SMQKDTPQEMEQTRSAVDEDRKMYLQAAIVRIMKARKVLRHNALIQEVISQSRARFNPSI 715

Query: 316  KAIKKRIEDLITRDYLERDKDNANTYRYLA 227
              IKK IE LI + Y+ER + +A+ Y Y+A
Sbjct: 716  SMIKKCIEVLIDKQYIERSQASADEYSYVA 745

>CUL2_MOUSE (Q9D4H8) Cullin-2 (CUL-2)|
          Length = 745

 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 43/150 (28%), Positives = 71/150 (47%), Gaps = 4/150 (2%)
 Frame = -2

Query: 664  EIVTQLNLSDDDVVRLLHSLSCAKYKILSKEPAGRTISPNDSFEFNSKFTDRMRRIKIPL 485
            E+     +++ ++ + + SL     K+++ +     I    SF  N  F+ +  + KI  
Sbjct: 598  ELQDSTQMNEKELTKTIKSL--LDVKMINHDSEKEDIDAESSFSLNMSFSSKRTKFKITT 655

Query: 484  PPXXXX----XXXXXXXXXDRRYAIDASIVRIMKSRKVMAHTQLVAECVEQLSRMFKPDF 317
                               DR+  + A+IVRIMK+RKV+ H  L+ E + Q    F P  
Sbjct: 656  SMQKDTPQELEQTRSAVDEDRKMYLQAAIVRIMKARKVLRHNALIQEVISQSRARFNPSI 715

Query: 316  KAIKKRIEDLITRDYLERDKDNANTYRYLA 227
              IKK IE LI + Y+ER + +A+ Y Y+A
Sbjct: 716  SMIKKCIEVLIDKQYIERSQASADEYSYVA 745

>CUL2_HUMAN (Q13617) Cullin-2 (CUL-2)|
          Length = 745

 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 43/150 (28%), Positives = 71/150 (47%), Gaps = 4/150 (2%)
 Frame = -2

Query: 664  EIVTQLNLSDDDVVRLLHSLSCAKYKILSKEPAGRTISPNDSFEFNSKFTDRMRRIKIPL 485
            E+     +++ ++ + + SL     K+++ +     I    SF  N  F+ +  + KI  
Sbjct: 598  ELQDSTQMNEKELTKTIKSL--LDVKMINHDSEKEDIDAESSFSLNMNFSSKRTKFKITT 655

Query: 484  PPXXXX----XXXXXXXXXDRRYAIDASIVRIMKSRKVMAHTQLVAECVEQLSRMFKPDF 317
                               DR+  + A+IVRIMK+RKV+ H  L+ E + Q    F P  
Sbjct: 656  SMQKDTPQEMEQTRSAVDEDRKMYLQAAIVRIMKARKVLRHNALIQEVISQSRARFNPSI 715

Query: 316  KAIKKRIEDLITRDYLERDKDNANTYRYLA 227
              IKK IE LI + Y+ER + +A+ Y Y+A
Sbjct: 716  SMIKKCIEVLIDKQYIERSQASADEYSYVA 745

>CUL2_CAEEL (Q17390) Cullin-2|
          Length = 776

 Score = 67.0 bits (162), Expect = 5e-11
 Identities = 34/70 (48%), Positives = 47/70 (67%)
 Frame = -2

Query: 436 RRYAIDASIVRIMKSRKVMAHTQLVAECVEQLSRMFKPDFKAIKKRIEDLITRDYLERDK 257
           R+Y ++ +IVRIMK+RKV+ H  LV E ++Q    F PD   IKK IEDLI + Y++R  
Sbjct: 708 RKYYMECAIVRIMKTRKVLKHNALVTEIMDQTKGRFSPDVPFIKKSIEDLIEKMYIQRTD 767

Query: 256 DNANTYRYLA 227
            N + Y+YLA
Sbjct: 768 QN-DEYQYLA 776

>CUL6_CAEEL (Q21346) Cullin-6|
          Length = 729

 Score = 63.9 bits (154), Expect = 4e-10
 Identities = 33/70 (47%), Positives = 44/70 (62%)
 Frame = -2

Query: 436 RRYAIDASIVRIMKSRKVMAHTQLVAECVEQLSRMFKPDFKAIKKRIEDLITRDYLERDK 257
           R+Y I A IVRIMK+RK + HT L+ E + QL   F P+ + IK  IE LI + Y+ R +
Sbjct: 660 RKYEIKACIVRIMKTRKSLTHTLLINEIISQLKSRFTPNVQMIKICIEILIEQLYIRRSE 719

Query: 256 DNANTYRYLA 227
           +  N Y YLA
Sbjct: 720 NEHNVYEYLA 729

>CUL1_SCHPO (O13790) Cullin-1 (Cul-1) (Cell division control 53 homolog)|
          Length = 767

 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 44/150 (29%), Positives = 72/150 (48%), Gaps = 4/150 (2%)
 Frame = -2

Query: 664  EIVTQLNLSDDDVVRLLHSLSCAKYKILSKEPAGRTISPNDSFEFNSKFTDRMRRIKIPL 485
            E+     LS D +  +L+    AK  +L      +   PN +++ N  F  +  R+++ L
Sbjct: 622  ELAKITGLSTDFLTGILNIFLKAKVLLLGDND--KLGDPNSTYKINENFRMKKIRVQLNL 679

Query: 484  P----PXXXXXXXXXXXXXDRRYAIDASIVRIMKSRKVMAHTQLVAECVEQLSRMFKPDF 317
            P                  DR+  + ++IVRIMK+R+ + H  LV E ++Q+   F P  
Sbjct: 680  PIRSEQKQESLETHKTIEEDRKLLLQSAIVRIMKARRTLKHVVLVKETIDQIKSRFTPKV 739

Query: 316  KAIKKRIEDLITRDYLERDKDNANTYRYLA 227
              IK+ I+ LI ++YLER     + Y YLA
Sbjct: 740  SDIKQCIDMLIEKEYLER--QGRDEYIYLA 767

>CUL1_CAEEL (Q17389) Cullin-1 (Abnormal cell lineage protein 19)|
          Length = 780

 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 32/70 (45%), Positives = 44/70 (62%)
 Frame = -2

Query: 436 RRYAIDASIVRIMKSRKVMAHTQLVAECVEQLSRMFKPDFKAIKKRIEDLITRDYLERDK 257
           R+  I A IVRIMK+RK + H QL+ E + QLS  FKP  + IK+ I  LI ++Y+ R +
Sbjct: 711 RKSVISACIVRIMKTRKRVQHQQLMTEVITQLSGRFKPKVEMIKRCIGSLIEKEYMLRTE 770

Query: 256 DNANTYRYLA 227
              + Y YLA
Sbjct: 771 GQKDLYEYLA 780

>CUL5_PONPY (Q5RB36) Cullin-5 (CUL-5)|
          Length = 780

 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 29/63 (46%), Positives = 42/63 (66%)
 Frame = -2

Query: 415 SIVRIMKSRKVMAHTQLVAECVEQLSRMFKPDFKAIKKRIEDLITRDYLERDKDNANTYR 236
           +I++IMK RK +++ QL  E VE L  MF P  K IK++IE LI   Y+ RD+ + NT+ 
Sbjct: 718 AIIQIMKMRKKISNAQLQTELVEILKNMFLPQKKMIKEQIEWLIEHKYIRRDESDINTFI 777

Query: 235 YLA 227
           Y+A
Sbjct: 778 YMA 780

>CUL5_HUMAN (Q93034) Cullin-5 (CUL-5) (Vasopressin-activated calcium-mobilizing|
           receptor) (VACM-1)
          Length = 780

 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 29/63 (46%), Positives = 42/63 (66%)
 Frame = -2

Query: 415 SIVRIMKSRKVMAHTQLVAECVEQLSRMFKPDFKAIKKRIEDLITRDYLERDKDNANTYR 236
           +I++IMK RK +++ QL  E VE L  MF P  K IK++IE LI   Y+ RD+ + NT+ 
Sbjct: 718 AIIQIMKMRKKISNAQLQTELVEILKNMFLPQKKMIKEQIEWLIEHKYIRRDESDINTFI 777

Query: 235 YLA 227
           Y+A
Sbjct: 778 YMA 780

>CUL5_RAT (Q9JJ31) Cullin-5 (CUL-5) (Vasopressin-activated calcium-mobilizing|
           receptor) (VACM-1)
          Length = 780

 Score = 57.0 bits (136), Expect = 5e-08
 Identities = 29/63 (46%), Positives = 42/63 (66%)
 Frame = -2

Query: 415 SIVRIMKSRKVMAHTQLVAECVEQLSRMFKPDFKAIKKRIEDLITRDYLERDKDNANTYR 236
           +I++IMK RK +++ QL  E VE L  MF P  K IK++IE LI   Y+ RD+ + NT+ 
Sbjct: 718 AIIQIMKMRKKISNAQLQTELVEILKNMFLPQKKMIKEQIEWLIEHKYIRRDEADINTFI 777

Query: 235 YLA 227
           Y+A
Sbjct: 778 YMA 780

>CDC53_YEAST (Q12018) Cell division control protein 53 (Cullin-A) (E3 ubiquitin|
           ligase complex SCF subunit CDC53)
          Length = 815

 Score = 56.6 bits (135), Expect = 6e-08
 Identities = 28/70 (40%), Positives = 44/70 (62%)
 Frame = -2

Query: 436 RRYAIDASIVRIMKSRKVMAHTQLVAECVEQLSRMFKPDFKAIKKRIEDLITRDYLERDK 257
           R+  ++A IVRIMK+++ + HT LV EC+ Q  + F      +K+ I+ LI + YL+R  
Sbjct: 747 RQIFLEACIVRIMKAKRNLPHTTLVNECIAQSHQRFNAKVSMVKRAIDSLIQKGYLQRG- 805

Query: 256 DNANTYRYLA 227
           D+  +Y YLA
Sbjct: 806 DDGESYAYLA 815

>CUL5_RABIT (Q29425) Cullin-5 (CUL-5) (Vasopressin-activated calcium-mobilizing|
           receptor) (VACM-1)
          Length = 780

 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 28/61 (45%), Positives = 40/61 (65%)
 Frame = -2

Query: 409 VRIMKSRKVMAHTQLVAECVEQLSRMFKPDFKAIKKRIEDLITRDYLERDKDNANTYRYL 230
           ++IMK RK +++ QL  E VE L  MF P  K IK++IE LI   Y+ RD+ + NT+ Y+
Sbjct: 720 IQIMKMRKKISNAQLQTELVEILKNMFLPQKKMIKEQIEWLIEHKYIRRDESDINTFIYM 779

Query: 229 A 227
           A
Sbjct: 780 A 780

>CUL5_MOUSE (Q9D5V5) Cullin-5 (CUL-5)|
          Length = 780

 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 28/63 (44%), Positives = 42/63 (66%)
 Frame = -2

Query: 415 SIVRIMKSRKVMAHTQLVAECVEQLSRMFKPDFKAIKKRIEDLITRDYLERDKDNANTYR 236
           +I++IMK RK +++ QL  E VE L  MF P  K IK+++E LI   Y+ RD+ + NT+ 
Sbjct: 718 AIIQIMKMRKKISNAQLQTELVEILKNMFLPQKKMIKEQMEWLIEHRYIRRDEADINTFI 777

Query: 235 YLA 227
           Y+A
Sbjct: 778 YMA 780

>CUL5_CAEEL (Q23639) Cullin-5|
          Length = 741

 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 28/70 (40%), Positives = 42/70 (60%)
 Frame = -2

Query: 436 RRYAIDASIVRIMKSRKVMAHTQLVAECVEQLSRMFKPDFKAIKKRIEDLITRDYLERDK 257
           R   +   IV+I+K+RK     QL  E VE L  +F P+ K IK++I+ LI   Y+ER  
Sbjct: 672 RELRVQEGIVKILKTRKTYTLAQLTMELVEILKPLFIPNRKIIKEQIDWLIENKYMERRA 731

Query: 256 DNANTYRYLA 227
           D+ NT+ Y++
Sbjct: 732 DDINTFVYIS 741

>CUL3_YEAST (P53202) Cullin-3 (Cullin-B)|
          Length = 744

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 42/156 (26%), Positives = 71/156 (45%), Gaps = 10/156 (6%)
 Frame = -2

Query: 664  EIVTQLNLSDDDVVRLLHSLSCA-KYKILSKEPAGRTISPNDSFEFNSKFTDRMRRIKIP 488
            EI    ++  DDV  L+ S+S   + KIL K  +    S N  F  N  F+   R++K+P
Sbjct: 593  EIYELTHIPIDDVKSLVMSMSTIPRCKILKKSSS----SGNMKFSVNYFFSSPNRKVKVP 648

Query: 487  L---PPXXXXXXXXXXXXXDRRY------AIDASIVRIMKSRKVMAHTQLVAECVEQLSR 335
            +   P                 Y       + A IVRIMK+   ++H QL+    ++   
Sbjct: 649  VIACPLPSQKSDNLATASSVDTYDNEIVMELSAIIVRIMKTEGKLSHQQLLERTTKRTQS 708

Query: 334  MFKPDFKAIKKRIEDLITRDYLERDKDNANTYRYLA 227
                    +K+ I+ LI ++Y++R+ D+ + Y YL+
Sbjct: 709  RLSLTPSILKRSIQLLIEKEYIQRNADDPSYYHYLS 744

>MEC10_CAEEL (P34886) Degenerin mec-10 (Mechanosensory abnormality protein 10)|
          Length = 724

 Score = 30.4 bits (67), Expect = 5.0
 Identities = 20/68 (29%), Positives = 31/68 (45%), Gaps = 2/68 (2%)
 Frame = +3

Query: 9   KXCKX*LVGYRGDSSNPELPTVSDDACTK*DQPGKIANRNPKNKLQASQQVLGARHGS-- 182
           + C   L+  R   S+P  P++         QP ++ N+N +  L+     +G  HGS  
Sbjct: 544 RTCFQELIIDRCGCSDPRFPSIGGV------QPCQVFNKNHRECLEKHTHQIGEIHGSFK 597

Query: 183 CHHQQACN 206
           C  QQ CN
Sbjct: 598 CRCQQPCN 605


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 88,623,656
Number of Sequences: 219361
Number of extensions: 1713281
Number of successful extensions: 4788
Number of sequences better than 10.0: 29
Number of HSP's better than 10.0 without gapping: 4613
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4775
length of database: 80,573,946
effective HSP length: 108
effective length of database: 56,882,958
effective search space used: 6427774254
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)