ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | rbags15d19 |
|---|---|
| Clone Library Name | barley_pub |
>KPK1_PHAVU (P15792) Protein kinase PVPK-1 (EC 2.7.11.1)| Length = 609 Score = 139 bits (349), Expect = 9e-33 Identities = 62/94 (65%), Positives = 76/94 (80%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 IFLYELL+G+TPF+G N TL NV+ Q L+FP+SP VS+ ARDLIRGLLVKEP+HRL Sbjct: 493 IFLYELLFGRTPFKGSANRATLFNVIGQPLRFPESPTVSFAARDLIRGLLVKEPQHRLAY 552 Query: 438 RKGAAEIKRHPFFQGLNWALIRWTAPPETPKSIV 337 R+GA EIK+HPFFQ +NWALIR PPE P+ ++ Sbjct: 553 RRGATEIKQHPFFQNVNWALIRCATPPEVPRQVI 586
>G11A_ORYSA (P47997) Protein kinase G11A (EC 2.7.11.1)| Length = 589 Score = 139 bits (349), Expect = 9e-33 Identities = 62/93 (66%), Positives = 77/93 (82%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 IFLYELL+GKTPF+G GN TL NV+ Q L+FP+ P VS+ ARDLIRGLLVKEP+ RLG Sbjct: 461 IFLYELLFGKTPFKGSGNRATLFNVIGQPLRFPEYPVVSFSARDLIRGLLVKEPQQRLGC 520 Query: 438 RKGAAEIKRHPFFQGLNWALIRWTAPPETPKSI 340 ++GA EIK+HPFF+G+NWALIR +PPE P+ + Sbjct: 521 KRGATEIKQHPFFEGVNWALIRCASPPEVPRPV 553
>KPK7_ARATH (Q05999) Putative serine/threonine-protein kinase PK7 (EC 2.7.11.1)| Length = 578 Score = 134 bits (336), Expect = 3e-31 Identities = 63/93 (67%), Positives = 75/93 (80%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 IFLYELL+G TPFRG N TL NVV Q L+FP+ P VS+ ARDLIRGLLVKEP+HRL Sbjct: 444 IFLYELLFGITPFRGGDNRATLFNVVGQPLRFPEHPNVSFAARDLIRGLLVKEPQHRLAY 503 Query: 438 RKGAAEIKRHPFFQGLNWALIRWTAPPETPKSI 340 R+GA EIK+HPFFQ +NWALIR T+PP+ P+ + Sbjct: 504 RRGATEIKQHPFFQSVNWALIRCTSPPQIPQPV 536
>PHOT2_ARATH (P93025) Phototropin-2 (EC 2.7.11.1) (Defective in chloroplast| avoidance protein 1) (Non phototropic hypocotyl 1-like protein 1) (NPH1-like 1) (AtKin7) Length = 915 Score = 101 bits (252), Expect = 2e-21 Identities = 50/97 (51%), Positives = 65/97 (67%), Gaps = 2/97 (2%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 I LYE+LYG+TPFRG +T N++ + L FP S VS R LI LL ++P RLGS Sbjct: 792 ILLYEMLYGRTPFRGKNRQKTFANILHKDLTFPSSIPVSLVGRQLINTLLNRDPSSRLGS 851 Query: 438 RKGAAEIKRHPFFQGLNWALIRWTAPP--ETPKSIVE 334 + GA EIK+H FF+G+NW LIR +PP + P SI+E Sbjct: 852 KGGANEIKQHAFFRGINWPLIRGMSPPPLDAPLSIIE 888
>PHOT1_ARATH (O48963) Phototropin-1 (EC 2.7.11.1) (Non-phototropic hypocotyl| protein 1) (Root phototropism protein 1) Length = 996 Score = 100 bits (249), Expect = 3e-21 Identities = 48/88 (54%), Positives = 62/88 (70%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 I +YE+LYG TPFRG +T TNV+ + LKFP S S Q + LI LL ++P+ RLG Sbjct: 880 ILMYEMLYGYTPFRGKTRQKTFTNVLQKDLKFPASIPASLQVKQLIFRLLQRDPKKRLGC 939 Query: 438 RKGAAEIKRHPFFQGLNWALIRWTAPPE 355 +GA E+K+H FF+G+NWALIR T PPE Sbjct: 940 FEGANEVKQHSFFKGINWALIRCTNPPE 967
>KAD5_SCHPO (Q09831) Probable serine/threonine-protein kinase C4G8.05 (EC| 2.7.11.1) Length = 566 Score = 94.4 bits (233), Expect = 2e-19 Identities = 44/94 (46%), Positives = 64/94 (68%), Gaps = 3/94 (3%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFP---DSPAVSYQARDLIRGLLVKEPEHR 448 I YE+LY TPF+G + T +N++ + + FP D+P++S ++LIR LLVK+ R Sbjct: 410 ILFYEMLYATTPFKGKNRNMTFSNILHKDVIFPEYADAPSISSLCKNLIRKLLVKDENDR 469 Query: 447 LGSRKGAAEIKRHPFFQGLNWALIRWTAPPETPK 346 LGS+ GAA++K HPFF+ + WAL+R T PP PK Sbjct: 470 LGSQAGAADVKLHPFFKNVQWALLRHTEPPIIPK 503
>KIN82_YEAST (P25341) Probable serine/threonine-protein kinase KIN82 (EC| 2.7.11.1) Length = 720 Score = 93.6 bits (231), Expect = 4e-19 Identities = 42/90 (46%), Positives = 62/90 (68%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 I +YE+L+G TPF+G ++ET +N++++ +KFP VS +DLI+ LL K RLGS Sbjct: 530 ILIYEMLFGCTPFKGDNSNETFSNILTKDVKFPHDKEVSKNCKDLIKKLLNKNEAKRLGS 589 Query: 438 RKGAAEIKRHPFFQGLNWALIRWTAPPETP 349 + GAA+IKRHPFF+ + W+ +R PP P Sbjct: 590 KSGAADIKRHPFFKKVQWSFLRNQDPPLIP 619
>NRC2_NEUCR (O42626) Serine/threonine-protein kinase nrc-2 (EC 2.7.11.1)| (Nonrepressible conidiation protein 2) Length = 623 Score = 93.2 bits (230), Expect = 5e-19 Identities = 43/93 (46%), Positives = 60/93 (64%), Gaps = 3/93 (3%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPD---SPAVSYQARDLIRGLLVKEPEHR 448 I +YE+LYG TPF+G + T N++ + + FPD +P +S + LIR LL+K+ R Sbjct: 457 ILIYEMLYGTTPFKGKNRNATFANILREDIPFPDHAGAPQISNLCKSLIRKLLIKDENRR 516 Query: 447 LGSRKGAAEIKRHPFFQGLNWALIRWTAPPETP 349 LG+R GA++IK HPFF+ WALIR PP P Sbjct: 517 LGARAGASDIKTHPFFRTTQWALIRHMKPPIVP 549
>KN8R_YEAST (P53739) Probable serine/threonine-protein kinase YNR047W (EC| 2.7.11.1) Length = 893 Score = 91.7 bits (226), Expect = 2e-18 Identities = 41/109 (37%), Positives = 66/109 (60%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 I +YE+L+G TPF+G +ET TN++ + FP++ +S +DLI+ LL K RLG Sbjct: 705 ILIYEMLFGFTPFKGDNTNETFTNILKNEVSFPNNNEISRTCKDLIKKLLTKNESKRLGC 764 Query: 438 RKGAAEIKRHPFFQGLNWALIRWTAPPETPKSIVEASTLTVAVARKKKE 292 + GAA++K+HPFF+ + W+L+R PP P + + KK++ Sbjct: 765 KMGAADVKKHPFFKKVQWSLLRNQEPPLIPVLSEDGYDFAKLSSNKKRQ 813
>CBK1_KLULA (P31034) Serine/threonine-protein kinase CBK1 (EC 2.7.11.1)| Length = 718 Score = 73.9 bits (180), Expect = 3e-13 Identities = 42/91 (46%), Positives = 52/91 (57%), Gaps = 2/91 (2%) Frame = -2 Query: 612 LYELLYGKTPFRGPGNDETLTNVVS--QGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 +YE L G PF ET +++ Q L+FPD +SY+A DLIR LL E+RLG Sbjct: 560 MYECLIGWPPFCSETPQETYRKIMNFEQTLQFPDDIHISYEAEDLIRRLLTHS-ENRLGR 618 Query: 438 RKGAAEIKRHPFFQGLNWALIRWTAPPETPK 346 GA EIK HPFF G++W IR P PK Sbjct: 619 HGGADEIKAHPFFSGVDWNTIRQVEAPYIPK 649
>CBK1_YEAST (P53894) Serine/threonine-protein kinase CBK1 (EC 2.7.11.1) (Cell| wall biosynthesis kinase) Length = 756 Score = 72.8 bits (177), Expect = 8e-13 Identities = 41/91 (45%), Positives = 52/91 (57%), Gaps = 2/91 (2%) Frame = -2 Query: 612 LYELLYGKTPFRGPGNDETLTNVVS--QGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 +YE L G PF ET +++ Q L+FPD +SY+A DLIR LL + RLG Sbjct: 601 MYECLIGWPPFCSETPQETYRKIMNFEQTLQFPDDIHISYEAEDLIRRLLT-HADQRLGR 659 Query: 438 RKGAAEIKRHPFFQGLNWALIRWTAPPETPK 346 GA EIK HPFF+G++W IR P PK Sbjct: 660 HGGADEIKSHPFFRGVDWNTIRQVEAPYIPK 690
>CBK1_CANGA (Q6FP74) Serine/threonine-protein kinase CBK1 (EC 2.7.11.1)| Length = 773 Score = 71.2 bits (173), Expect = 2e-12 Identities = 40/91 (43%), Positives = 53/91 (58%), Gaps = 2/91 (2%) Frame = -2 Query: 612 LYELLYGKTPFRGPGNDETLTNVVS--QGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 +YE L G PF ET +++ Q L+FP+ +SY+A DLIR LL + RLG Sbjct: 615 MYECLIGWPPFCSETPQETYRKIMNFEQTLQFPEDVHISYEAEDLIRRLLTHSNQ-RLGR 673 Query: 438 RKGAAEIKRHPFFQGLNWALIRWTAPPETPK 346 + GA EIK HPFF+G++W IR P PK Sbjct: 674 QGGADEIKSHPFFRGVDWNTIRQVEAPYIPK 704
>CBK1_ASHGO (Q754N7) Serine/threonine-protein kinase CBK1 (EC 2.7.11.1)| Length = 719 Score = 70.9 bits (172), Expect = 3e-12 Identities = 42/91 (46%), Positives = 52/91 (57%), Gaps = 2/91 (2%) Frame = -2 Query: 612 LYELLYGKTPFRGPGNDETLTNVVS--QGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 +YE L G PF ET +++ Q L FPD +SY+A DLIR LL + RLG Sbjct: 561 MYECLIGWPPFCSETPQETYRKIMNFEQTLVFPDDIHISYEAEDLIRRLL-SHADERLG- 618 Query: 438 RKGAAEIKRHPFFQGLNWALIRWTAPPETPK 346 R GA EIK HPFF+G++W IR P PK Sbjct: 619 RHGANEIKNHPFFRGVDWETIRQVGAPYIPK 649
>DMPK_MOUSE (P54265) Myotonin-protein kinase (EC 2.7.11.1) (Myotonic dystrophy| protein kinase) (MDPK) (DM-kinase) (DMK) (DMPK) (MT-PK) Length = 631 Score = 67.8 bits (164), Expect = 2e-11 Identities = 41/93 (44%), Positives = 54/93 (58%), Gaps = 3/93 (3%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVS--QGLKFP-DSPAVSYQARDLIRGLLVKEPEHR 448 +F YE+ YG+TPF ET +V + L P V +A+DLIRGLL E R Sbjct: 266 VFAYEMFYGQTPFYADSTAETYAKIVHYREHLSLPLADTVVPEEAQDLIRGLLCPA-EIR 324 Query: 447 LGSRKGAAEIKRHPFFQGLNWALIRWTAPPETP 349 LG R GA + ++HPFF GL+W +R + PP TP Sbjct: 325 LG-RGGAGDFQKHPFFFGLDWEGLRDSVPPFTP 356
>GAD8_SCHPO (Q9P7J8) Serine/threonine-protein kinase gad8 (EC 2.7.11.1)| Length = 569 Score = 66.6 bits (161), Expect = 5e-11 Identities = 33/78 (42%), Positives = 48/78 (61%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 + LYE++ G PF +E ++ L+FPD+ + +A+DL+ GLL + PE RLGS Sbjct: 416 VLLYEMITGLPPFYDENINEMYRKILQDPLRFPDN--IDEKAKDLLSGLLTRAPEKRLGS 473 Query: 438 RKGAAEIKRHPFFQGLNW 385 GA EIK HPFF ++W Sbjct: 474 -GGAQEIKNHPFFDDIDW 490
>SCK2_SCHPO (Q10364) Serine/threonine-protein kinase sck2 (EC 2.7.11.1)| Length = 646 Score = 65.9 bits (159), Expect = 9e-11 Identities = 33/92 (35%), Positives = 53/92 (57%), Gaps = 2/92 (2%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 + LYE+ G +PF + N+V ++FP +S +ARDLI+ LL + P+HRLG+ Sbjct: 456 VLLYEMTCGWSPFYADNTQQLYKNIVFGKVRFPRG-LLSVEARDLIKLLLNRNPKHRLGA 514 Query: 438 RKGAAEIKRHPFFQGLNWALI--RWTAPPETP 349 E+ +HPFF G++W + + +PP P Sbjct: 515 HGDVEEVMKHPFFDGIDWKKLAAKEISPPFKP 546
>ORB6_SCHPO (O13310) Serine/threonine-protein kinase orb6 (EC 2.7.11.1)| Length = 469 Score = 65.5 bits (158), Expect = 1e-10 Identities = 41/97 (42%), Positives = 58/97 (59%), Gaps = 4/97 (4%) Frame = -2 Query: 612 LYELLYGKTPFRGPGNDETLTNVVS--QGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 ++E L G PF + ET +++ + L FP+ +S +ARDL+ L+ + EHRLG Sbjct: 322 MFECLIGWPPFCSENSHETYRKIINWRETLTFPNDIHLSIEARDLMDRLMT-DSEHRLG- 379 Query: 438 RKGAAEIKRHPFFQGLNWALIRWTAPPETP--KSIVE 334 R GA EI +HPFF G++W IR TA P P KSI + Sbjct: 380 RGGAIEIMQHPFFTGIDWDHIRETAAPFIPNLKSITD 416
>PKN1_RAT (Q63433) Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protein| kinase C-like 1) (Protein-kinase C-related kinase 1) (Protein kinase C-like PKN) (Serine-threonine protein kinase N) (Protease-activated kinase 1) (PAK-1) Length = 946 Score = 64.7 bits (156), Expect = 2e-10 Identities = 35/93 (37%), Positives = 57/93 (61%), Gaps = 3/93 (3%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 +FLYE+L G++PF G +E ++V+ +++P +S +A ++R LL + PE RLGS Sbjct: 807 VFLYEMLVGESPFPGDDEEEVFDSIVNDEVRYP--RFLSAEAIGIMRRLLRRNPERRLGS 864 Query: 438 -RKGAAEIKRHPFFQGLNW--ALIRWTAPPETP 349 + A ++K+ PFF+ L+W L R PP P Sbjct: 865 TERDAEDVKKQPFFRTLDWDALLARRLPPPFVP 897
>CBK1_YARLI (Q6CFS5) Serine/threonine-protein kinase CBK1 (EC 2.7.11.1)| Length = 588 Score = 64.7 bits (156), Expect = 2e-10 Identities = 41/99 (41%), Positives = 57/99 (57%), Gaps = 4/99 (4%) Frame = -2 Query: 612 LYELLYGKTPFRGPGNDETLTNVVS--QGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 ++E L G PF ET +++ + L+FPD +S ++ DLIR LL E+RLG Sbjct: 446 MFECLVGWPPFCSEQPRETYHKIINWRETLQFPDDVHLSPESEDLIRRLLTSS-ENRLGR 504 Query: 438 RKGAAEIKRHPFFQGLNWALIRWTAPPETPK--SIVEAS 328 GA EIK HPFF+G++W+ IR P PK SI + S Sbjct: 505 IGGANEIKSHPFFRGVDWSSIREFNAPFVPKLSSITDTS 543
>KPC2_CAEEL (P90980) Protein kinase C-like 2 (EC 2.7.11.13) (PKC2)| Length = 682 Score = 64.7 bits (156), Expect = 2e-10 Identities = 37/104 (35%), Positives = 54/104 (51%), Gaps = 6/104 (5%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLG- 442 + L+E+L G+ PF G DE T + + +P S +S +A L + LL+K P RLG Sbjct: 535 VLLFEMLAGQPPFDGEDEDELFTAITEHNVSYPKS--LSKEAVSLCKALLIKNPSKRLGC 592 Query: 441 ---SRKGAAEIKRHPFFQGLNWALI--RWTAPPETPKSIVEAST 325 + +IK HPFF+ ++W I R PP PK + ST Sbjct: 593 TGDDESASRDIKEHPFFRRIDWFKIETRQIQPPFKPKLKTDRST 636
>DMPK_HUMAN (Q09013) Myotonin-protein kinase (EC 2.7.11.1) (Myotonic dystrophy| protein kinase) (MDPK) (DM-kinase) (DMK) (DMPK) (MT-PK) Length = 639 Score = 64.7 bits (156), Expect = 2e-10 Identities = 40/93 (43%), Positives = 52/93 (55%), Gaps = 3/93 (3%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVV--SQGLKFP-DSPAVSYQARDLIRGLLVKEPEHR 448 +F YE+ YG+TPF ET +V + L P V +ARD I+ LL PE R Sbjct: 276 VFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLVDEGVPEEARDFIQRLLCP-PETR 334 Query: 447 LGSRKGAAEIKRHPFFQGLNWALIRWTAPPETP 349 LG R GA + + HPFF GL+W +R + PP TP Sbjct: 335 LG-RGGAGDFRTHPFFFGLDWDGLRDSVPPFTP 366
>KPK1_ARATH (P42818) Serine/threonine-protein kinase AtPK1/AtPK6 (EC 2.7.11.1)| Length = 465 Score = 64.3 bits (155), Expect = 3e-10 Identities = 36/79 (45%), Positives = 49/79 (62%), Gaps = 1/79 (1%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 I LYE+L GK PF G + +V +K P +S +A +++GLL KEPE RLGS Sbjct: 319 ILLYEMLTGKPPFLG-SKGKIQQKIVKDKIKLPQF--LSNEAHAILKGLLQKEPERRLGS 375 Query: 438 -RKGAAEIKRHPFFQGLNW 385 GA EIK+H +F+G+NW Sbjct: 376 GLSGAEEIKQHKWFKGINW 394
>KS6A4_HUMAN (O75676) Ribosomal protein S6 kinase alpha-4 (EC 2.7.11.1) (Nuclear| mitogen-and stress-activated protein kinase 2) (90 kDa ribosomal protein S6 kinase 4) (Ribosomal protein kinase B) (RSKB) Length = 772 Score = 64.3 bits (155), Expect = 3e-10 Identities = 36/84 (42%), Positives = 51/84 (60%), Gaps = 3/84 (3%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKF--PDSPAVSYQARDLIRGLLVKEPEHRL 445 I L+ELL G +PF G T V + LK P P + A+DL++ LL K+P+ RL Sbjct: 226 ILLFELLTGASPFTLEGERNTQAEVSRRILKCSPPFPPRIGPVAQDLLQRLLCKDPKKRL 285 Query: 444 GSR-KGAAEIKRHPFFQGLNWALI 376 G+ +GA E++ HPFFQGL+W + Sbjct: 286 GAGPQGAQEVRNHPFFQGLDWVAL 309 Score = 32.3 bits (72), Expect = 1.1 Identities = 22/67 (32%), Positives = 34/67 (50%), Gaps = 9/67 (13%) Frame = -2 Query: 618 IFLYELLYGKTPFRGP---GNDETLTNV---VSQGLKFPDSPA---VSYQARDLIRGLLV 466 + LY +L G+ PF+G G + + +G D A VS +A++L+RGLL Sbjct: 597 VILYMMLSGQVPFQGASGQGGQSQAAEIMCKIREGRFSLDGEAWQGVSEEAKELVRGLLT 656 Query: 465 KEPEHRL 445 +P RL Sbjct: 657 VDPAKRL 663
>AKT1_DROME (Q8INB9) RAC serine/threonine-protein kinase (EC 2.7.11.1)| (DRAC-PK) (Akt) (Dakt1) (Protein kinase B) (PKB) Length = 611 Score = 63.9 bits (154), Expect = 4e-10 Identities = 33/101 (32%), Positives = 59/101 (58%), Gaps = 3/101 (2%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 + +YE++ G+ PF +D T ++ + +KFP + ++ +A++L+ GLL K+P+ RLG Sbjct: 452 VVMYEMICGRLPFYNRDHDVLFTLILVEEVKFPRN--ITDEAKNLLAGLLAKDPKKRLGG 509 Query: 438 RK-GAAEIKRHPFFQGLNWA--LIRWTAPPETPKSIVEAST 325 K EI+ HPFF +NW +++ PP P+ + T Sbjct: 510 GKDDVKEIQAHPFFASINWTDLVLKKIPPPFKPQVTSDTDT 550
>PKN2_HUMAN (Q16513) Serine/threonine-protein kinase N2 (EC 2.7.11.13) (Protein| kinase C-like 2) (Protein-kinase C-related kinase 2) Length = 984 Score = 63.5 bits (153), Expect = 5e-10 Identities = 32/93 (34%), Positives = 58/93 (62%), Gaps = 3/93 (3%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLG- 442 + +YE+L G++PF G +E ++V+ +++P +S +A ++R LL + PE RLG Sbjct: 845 VLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYP--RFLSTEAISIMRRLLRRNPERRLGA 902 Query: 441 SRKGAAEIKRHPFFQGLNWALI--RWTAPPETP 349 S K A ++K+HPFF+ ++W+ + + PP P Sbjct: 903 SEKDAEDVKKHPFFRLIDWSALMDKKVKPPFIP 935
>SCK1_SCHPO (P50530) Serine/threonine-protein kinase sck1 (EC 2.7.11.1)| Length = 696 Score = 63.5 bits (153), Expect = 5e-10 Identities = 31/92 (33%), Positives = 49/92 (53%), Gaps = 2/92 (2%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 + ++E+ G +PF P + N+ ++FP +S + R +RGLL + P HRLG+ Sbjct: 492 VLVFEMCCGWSPFYAPDVQQMYRNIAFGKVRFPKG-VLSSEGRSFVRGLLNRNPNHRLGA 550 Query: 438 RKGAAEIKRHPFFQGLNWALI--RWTAPPETP 349 E+K HPFF +NW L+ + PP P Sbjct: 551 VADTTELKEHPFFADINWDLLSKKKVQPPFKP 582
>KPK19_ARATH (Q39030) Serine/threonine-protein kinase AtPK19 (EC 2.7.11.1)| (Ribosomal-protein S6 kinase homolog) Length = 471 Score = 63.2 bits (152), Expect = 6e-10 Identities = 36/79 (45%), Positives = 48/79 (60%), Gaps = 1/79 (1%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 I LYE+L GK PF G + +V +K P +S +A L++GLL KEPE RLGS Sbjct: 325 ILLYEMLTGKPPFLG-SKGKIQQKIVKDKIKLPQF--LSNEAHALLKGLLQKEPERRLGS 381 Query: 438 -RKGAAEIKRHPFFQGLNW 385 GA EIK+H +F+ +NW Sbjct: 382 GPSGAEEIKKHKWFKAINW 400
>AKT3_MOUSE (Q9WUA6) RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma) Length = 479 Score = 62.8 bits (151), Expect = 8e-10 Identities = 34/101 (33%), Positives = 56/101 (55%), Gaps = 3/101 (2%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 + +YE++ G+ PF +++ ++ + +KFP + +S A+ L+ GLL+K+P RLG Sbjct: 334 VVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRT--LSSDAKSLLSGLLIKDPNKRLGG 391 Query: 438 RKG-AAEIKRHPFFQGLNWALI--RWTAPPETPKSIVEAST 325 A EI RH FF G+NW + + PP P+ E T Sbjct: 392 GPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQVTSETDT 432
>AKT3_HUMAN (Q9Y243) RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma) (STK-2) Length = 479 Score = 62.8 bits (151), Expect = 8e-10 Identities = 34/101 (33%), Positives = 56/101 (55%), Gaps = 3/101 (2%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 + +YE++ G+ PF +++ ++ + +KFP + +S A+ L+ GLL+K+P RLG Sbjct: 334 VVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRT--LSSDAKSLLSGLLIKDPNKRLGG 391 Query: 438 RKG-AAEIKRHPFFQGLNWALI--RWTAPPETPKSIVEAST 325 A EI RH FF G+NW + + PP P+ E T Sbjct: 392 GPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQVTSETDT 432
>KPC1_DROME (P05130) Protein kinase C, brain isozyme (EC 2.7.11.13) (PKC)| (dPKC53E(BR)) Length = 679 Score = 62.8 bits (151), Expect = 8e-10 Identities = 32/94 (34%), Positives = 51/94 (54%), Gaps = 3/94 (3%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLG- 442 + LYE+L G+ PF G +E + + +P S +S +A++ +G L K+P RLG Sbjct: 537 VLLYEMLVGQPPFDGEDEEELFAAITDHNVSYPKS--LSKEAKEACKGFLTKQPNKRLGC 594 Query: 441 SRKGAAEIKRHPFFQGLNWALI--RWTAPPETPK 346 G +++ HPFF+ ++W I R PP PK Sbjct: 595 GSSGEEDVRLHPFFRRIDWEKIENREVQPPFKPK 628
>PKN1_MOUSE (P70268) Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protein| kinase C-like 1) (Protein-kinase C-related kinase 1) (Protein kinase C-like PKN) (Serine-threonine protein kinase N) Length = 946 Score = 62.8 bits (151), Expect = 8e-10 Identities = 34/93 (36%), Positives = 55/93 (59%), Gaps = 3/93 (3%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 + LYE+L G++PF G +E ++V+ +++P +S +A ++R LL + PE RLGS Sbjct: 807 VLLYEMLVGESPFPGDDEEEVFDSIVNDEVRYP--RFLSAEAIGIMRRLLRRNPERRLGS 864 Query: 438 -RKGAAEIKRHPFFQGLNW--ALIRWTAPPETP 349 + A ++K+ PFF+ L W L R PP P Sbjct: 865 TERDAEDVKKQPFFRSLGWDVLLARRLPPPFVP 897
>CEK1_SCHPO (P38938) Serine/threonine-protein kinase cek1 (EC 2.7.11.1)| Length = 1338 Score = 62.4 bits (150), Expect = 1e-09 Identities = 36/99 (36%), Positives = 51/99 (51%), Gaps = 2/99 (2%) Frame = -2 Query: 612 LYELLYGKTPFRGPGNDETLTNVVSQGLKFPDS--PAVSYQARDLIRGLLVKEPEHRLGS 439 ++E L+G PF D+ N++++ + +P A S A DLI LL P +RLG+ Sbjct: 887 VFEFLFGYPPFNAETPDQVFQNILARRINWPAEVFTAESSVALDLIDRLLCMNPANRLGA 946 Query: 438 RKGAAEIKRHPFFQGLNWALIRWTAPPETPKSIVEASTL 322 G EIK HPFF+ +NW I PP PK T+ Sbjct: 947 N-GVEEIKAHPFFKSVNWDTILEEDPPFVPKPFSPEDTV 984
>MRCKA_RAT (O54874) Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1)| (CDC42-binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) Length = 1732 Score = 62.4 bits (150), Expect = 1e-09 Identities = 37/94 (39%), Positives = 54/94 (57%), Gaps = 3/94 (3%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVS--QGLKFPDSPA-VSYQARDLIRGLLVKEPEHR 448 + +YE+LYG+TPF ET +++ + +FP VS A+DLIR L+ EHR Sbjct: 270 VCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPTQVTDVSENAKDLIRRLICSR-EHR 328 Query: 447 LGSRKGAAEIKRHPFFQGLNWALIRWTAPPETPK 346 LG + G + K+HPFF G++W IR P P+ Sbjct: 329 LG-QNGIEDFKKHPFFSGIDWDNIRNCEAPYIPE 361
>KS6AA_XENLA (P10665) Ribosomal protein S6 kinase 2 alpha (EC 2.7.11.1)| (Ribosomal protein S6 kinase II alpha) (S6KII-alpha) (P90-RSK) (MAP kinase-activated protein kinase 1) (MAPK-activated protein kinase 1) (MAPKAP kinase 1) (MAPKAPK-1) Length = 733 Score = 62.4 bits (150), Expect = 1e-09 Identities = 35/93 (37%), Positives = 54/93 (58%), Gaps = 3/93 (3%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 + ++E+L G PF+G ET+T ++ L P +S +A+ L+R L + P +RLGS Sbjct: 250 VLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQ--FLSNEAQSLLRALFKRNPTNRLGS 307 Query: 438 -RKGAAEIKRHPFFQGLNWALI--RWTAPPETP 349 +GA EIKR PFF ++W + R +PP P Sbjct: 308 AMEGAEEIKRQPFFSTIDWNKLFRREMSPPFKP 340
>KS6AA_CHICK (P18652) Ribosomal protein S6 kinase 2 alpha (EC 2.7.11.1)| (Ribosomal protein S6 kinase II alpha) (S6KII-alpha) (P90-RSK) (MAP kinase-activated protein kinase 1) (MAPK-activated protein kinase 1) (MAPKAP kinase 1) (MAPKAPK-1) Length = 752 Score = 62.4 bits (150), Expect = 1e-09 Identities = 35/93 (37%), Positives = 53/93 (56%), Gaps = 3/93 (3%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 + ++E+L G PF+G ET+T ++ L P +S +A+ L+R L + P +RLGS Sbjct: 268 VLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQF--LSAEAQSLLRALFKRNPANRLGS 325 Query: 438 RK-GAAEIKRHPFFQGLNWALI--RWTAPPETP 349 GA EIKRHPF+ ++W + R PP P Sbjct: 326 GPDGAEEIKRHPFYSTIDWNKLYRREIKPPFKP 358
>PKN1_HUMAN (Q16512) Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protein| kinase C-like 1) (Protein-kinase C-related kinase 1) (Protein kinase C-like PKN) (Serine-threonine protein kinase N) (Protein kinase PKN-alpha) Length = 942 Score = 62.0 bits (149), Expect = 1e-09 Identities = 34/93 (36%), Positives = 55/93 (59%), Gaps = 3/93 (3%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLG- 442 + LYE+L G++PF G +E ++V+ +++P +S +A ++R LL + PE RLG Sbjct: 803 VLLYEMLVGESPFPGDDEEEVFDSIVNDEVRYP--RFLSAEAIGIMRRLLRRNPERRLGS 860 Query: 441 SRKGAAEIKRHPFFQGLNW--ALIRWTAPPETP 349 S + A ++K+ PFF+ L W L R PP P Sbjct: 861 SERDAEDVKKQPFFRTLGWEALLARRLPPPFVP 893
>MRCKA_HUMAN (Q5VT25) Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1)| (CDC42-binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha Length = 1732 Score = 62.0 bits (149), Expect = 1e-09 Identities = 38/95 (40%), Positives = 54/95 (56%), Gaps = 4/95 (4%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPA----VSYQARDLIRGLLVKEPEH 451 + +YE+LYG+TPF ET +++ +F PA VS A+DLIR L+ EH Sbjct: 270 VCMYEMLYGETPFYAESLVETYGKIMNHKERF-QFPAQVTDVSENAKDLIRRLICSR-EH 327 Query: 450 RLGSRKGAAEIKRHPFFQGLNWALIRWTAPPETPK 346 RLG + G + K+HPFF G++W IR P P+ Sbjct: 328 RLG-QNGIEDFKKHPFFSGIDWDNIRNCEAPYIPE 361
>CBK1_PNECA (Q6TGC6) Serine/threonine-protein kinase CBK1 (EC 2.7.11.1)| Length = 507 Score = 62.0 bits (149), Expect = 1e-09 Identities = 41/99 (41%), Positives = 55/99 (55%), Gaps = 4/99 (4%) Frame = -2 Query: 612 LYELLYGKTPFRGPGNDETLTNVVS--QGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 ++E L G PF ET +++ + L FP+ +S +A DLIR LL + RLG Sbjct: 361 MFECLIGWPPFCSENAHETYRKIINWRENLYFPEDLHLSAEAEDLIRKLLTSA-DQRLG- 418 Query: 438 RKGAAEIKRHPFFQGLNWALIRWTAPPETP--KSIVEAS 328 R GA +IK HPFF+G+NW IR P P KSI + S Sbjct: 419 RYGANDIKLHPFFRGVNWDTIREINAPFIPQLKSITDTS 457
>PKN2_MOUSE (Q8BWW9) Serine/threonine-protein kinase N2 (EC 2.7.11.13) (Protein| kinase C-like 2) (Protein-kinase C-related kinase 2) Length = 983 Score = 61.6 bits (148), Expect = 2e-09 Identities = 31/93 (33%), Positives = 57/93 (61%), Gaps = 3/93 (3%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 + +YE+L G++PF G +E ++V+ +++P +S +A ++R LL + PE RLG+ Sbjct: 844 VLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYP--RFLSTEAISIMRRLLRRNPERRLGA 901 Query: 438 -RKGAAEIKRHPFFQGLNWALI--RWTAPPETP 349 K A ++K+HPFF+ +W+ + + PP P Sbjct: 902 GEKDAEDVKKHPFFRLTDWSALMDKKVKPPFVP 934
>PKN2_RAT (O08874) Serine/threonine-protein kinase N2 (EC 2.7.11.13) (Protein| kinase C-like 2) (Protein-kinase C-related kinase 2) (Protease-activated kinase 2) (PAK-2) (Fragment) Length = 842 Score = 61.6 bits (148), Expect = 2e-09 Identities = 32/93 (34%), Positives = 57/93 (61%), Gaps = 3/93 (3%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 + +YE+L G++PF G +E ++V+ +++P +S +A ++R LL + PE RLG+ Sbjct: 709 VLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYP--RFLSTEAISIMRRLLRRNPERRLGA 766 Query: 438 -RKGAAEIKRHPFFQGLNWA--LIRWTAPPETP 349 K A ++K+HPFF+ +W+ L + PP P Sbjct: 767 GEKDAEDVKKHPFFRLTDWSALLDKKVKPPFVP 799
>KS6AB_XENLA (P10666) Ribosomal protein S6 kinase 2 beta (EC 2.7.11.1)| (Ribosomal protein S6 kinase II beta) (S6KII-beta) (P90-RSK) Length = 629 Score = 61.2 bits (147), Expect = 2e-09 Identities = 34/93 (36%), Positives = 54/93 (58%), Gaps = 3/93 (3%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 + ++E+L G PF+G ET+T ++ L P +S +A+ L+R L + +RLGS Sbjct: 250 VLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQF--LSNEAQSLLRALFKRNATNRLGS 307 Query: 438 R-KGAAEIKRHPFFQGLNWALI--RWTAPPETP 349 +GA E+KRHPFF ++W + R +PP P Sbjct: 308 GVEGAEELKRHPFFSTIDWNKLYRRELSPPFKP 340
>KS6B2_HUMAN (Q9UBS0) Ribosomal protein S6 kinase beta-2 (EC 2.7.11.1) (S6K2)| (70 kDa ribosomal protein S6 kinase 2) (p70-S6KB) (p70 ribosomal S6 kinase beta) (p70 S6Kbeta) (p70 S6 kinase beta) (S6K-beta) (p70-beta) (S6 kinase-related kinase) (SRK) (Serin Length = 482 Score = 61.2 bits (147), Expect = 2e-09 Identities = 30/87 (34%), Positives = 49/87 (56%), Gaps = 2/87 (2%) Frame = -2 Query: 612 LYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGSRK 433 +Y++L G PF +T+ ++ L P P ++ ARDL++ L + P R+G Sbjct: 259 MYDMLTGSPPFTAENRKKTMDKIIRGKLALP--PYLTPDARDLVKKFLKRNPSQRIGGGP 316 Query: 432 G-AAEIKRHPFFQGLNW-ALIRWTAPP 358 G AA+++RHPFF+ +NW L+ W P Sbjct: 317 GDAADVQRHPFFRHMNWDDLLAWRVDP 343
>AKT3_RAT (Q63484) RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma) Length = 454 Score = 60.8 bits (146), Expect = 3e-09 Identities = 33/101 (32%), Positives = 55/101 (54%), Gaps = 3/101 (2%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRL-G 442 + +YE++ G+ PF +++ ++ + +KFP + +S A+ L+ GLL+K+P RL G Sbjct: 334 VVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRT--LSSDAKSLLSGLLIKDPNKRLGG 391 Query: 441 SRKGAAEIKRHPFFQGLNWALI--RWTAPPETPKSIVEAST 325 EI RH FF G+NW + + PP P+ E T Sbjct: 392 GPDDPKEIMRHSFFSGVNWQDVYDKKLVPPFKPQVTSETDT 432
>KS6A4_MOUSE (Q9Z2B9) Ribosomal protein S6 kinase alpha-4 (EC 2.7.11.1) (Nuclear| mitogen-and stress-activated protein kinase 2) (90 kDa ribosomal protein S6 kinase 4) (RSK-like protein kinase) (RLSK) Length = 773 Score = 60.8 bits (146), Expect = 3e-09 Identities = 36/81 (44%), Positives = 49/81 (60%), Gaps = 3/81 (3%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKF--PDSPAVSYQARDLIRGLLVKEPEHRL 445 I L+ELL G +PF G T V + LK P + A+DL++ LL K+P+ RL Sbjct: 226 ILLFELLTGASPFTLEGERNTQAEVSRRILKCSPPFPLRIGPVAQDLLQRLLCKDPKKRL 285 Query: 444 GSR-KGAAEIKRHPFFQGLNW 385 G+ +GA E+K HPFFQGL+W Sbjct: 286 GAGPQGAQEVKSHPFFQGLDW 306 Score = 32.3 bits (72), Expect = 1.1 Identities = 22/67 (32%), Positives = 34/67 (50%), Gaps = 9/67 (13%) Frame = -2 Query: 618 IFLYELLYGKTPFRGP---GNDETLTNV---VSQGLKFPDSPA---VSYQARDLIRGLLV 466 + LY +L G+ PF+G G + + +G D A VS +A++L+RGLL Sbjct: 597 VILYMMLSGQVPFQGASGQGGQSQAAEIMCKIREGRFSLDGEAWQGVSEEAKELVRGLLT 656 Query: 465 KEPEHRL 445 +P RL Sbjct: 657 VDPAKRL 663
>MRCKG_HUMAN (Q6DT37) Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1)| (CDC42-binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma Length = 1551 Score = 60.8 bits (146), Expect = 3e-09 Identities = 37/91 (40%), Positives = 54/91 (59%), Gaps = 3/91 (3%) Frame = -2 Query: 609 YELLYGKTPFRGPGNDETLTNVVSQG--LKFP-DSPAVSYQARDLIRGLLVKEPEHRLGS 439 YELL+G+TPF ET +++ L+FP D P V A+DLIR LL ++ E RLG Sbjct: 267 YELLFGETPFYAESLVETYGKIMNHEDHLQFPPDVPDVPASAQDLIRQLLCRQ-EERLG- 324 Query: 438 RKGAAEIKRHPFFQGLNWALIRWTAPPETPK 346 R G + + HPFF+G++W + + P P+ Sbjct: 325 RGGLDDFRNHPFFEGVDWERLASSTAPYIPE 355
>CBK1_DEBHA (Q6BLJ9) Serine/threonine-protein kinase CBK1 (EC 2.7.11.1)| Length = 716 Score = 60.8 bits (146), Expect = 3e-09 Identities = 36/91 (39%), Positives = 51/91 (56%), Gaps = 2/91 (2%) Frame = -2 Query: 612 LYELLYGKTPFRGPGNDETLTNVVS--QGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 ++E L G PF ET +++ + L+ PD +S ++ DLIR LL E+RLG Sbjct: 563 MFECLIGWPPFCSETPHETYRKILNWQETLQIPDDIHLSPESEDLIRKLLTNA-ENRLGR 621 Query: 438 RKGAAEIKRHPFFQGLNWALIRWTAPPETPK 346 GA E+K HPFF+G++W IR P PK Sbjct: 622 YNGADELKLHPFFRGVDWDTIRKVDAPFIPK 652
>PKN3_MOUSE (Q8K045) Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein| kinase PKN-beta) (Protein-kinase C-related kinase 3) Length = 878 Score = 60.5 bits (145), Expect = 4e-09 Identities = 38/93 (40%), Positives = 50/93 (53%), Gaps = 3/93 (3%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 + LYE+L G+ PF G +E +VS + P +S Q +LI+ LL K PE RLG+ Sbjct: 736 VLLYEMLVGECPFPGDTEEEVFECIVSADVPCPH--FLSVQGLELIQKLLQKSPEKRLGA 793 Query: 438 -RKGAAEIKRHPFFQGLNW--ALIRWTAPPETP 349 + A EIK PFF+ NW L R PP P Sbjct: 794 GERDAEEIKVQPFFRTTNWQALLARTVQPPFVP 826
>KPCA_MOUSE (P20444) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 60.5 bits (145), Expect = 4e-09 Identities = 31/94 (32%), Positives = 53/94 (56%), Gaps = 3/94 (3%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLG- 442 + LYE+L G+ PF G DE +++ + +P S +S +A + +GL+ K+P RLG Sbjct: 525 VLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKS--LSKEAVSICKGLMTKQPAKRLGC 582 Query: 441 SRKGAAEIKRHPFFQGLNWALI--RWTAPPETPK 346 +G +++ H FF+ ++W + R PP PK Sbjct: 583 GPEGERDVREHAFFRRIDWEKLENREIQPPFKPK 616
>KPC3_DROME (P13678) Protein kinase C (EC 2.7.11.13) (PKC) (dPKC98F)| Length = 634 Score = 60.5 bits (145), Expect = 4e-09 Identities = 31/93 (33%), Positives = 50/93 (53%), Gaps = 2/93 (2%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 + +YE++ G+ PF DE +++ + +P +S +A +++G L K PE RLG Sbjct: 490 VLMYEMMAGQPPFEADNEDELFDSIMHDDVLYP--VWLSREAVSILKGFLTKNPEQRLGC 547 Query: 438 RKGAAEIKRHPFFQGLNWALI--RWTAPPETPK 346 EI++HPFF L+W + R PP PK Sbjct: 548 TGDENEIRKHPFFAKLDWKELEKRNIKPPFRPK 580
>KS6B1_RAT (P67999) Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1)| (Ribosomal protein S6 kinase I) (S6K) (p70-S6K) Length = 525 Score = 60.1 bits (144), Expect = 5e-09 Identities = 33/91 (36%), Positives = 51/91 (56%), Gaps = 3/91 (3%) Frame = -2 Query: 612 LYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGSRK 433 +Y++L G PF G +T+ ++ L P P ++ +ARDL++ LL + RLG+ Sbjct: 283 MYDMLTGAPPFTGENRKKTIDKILKCKLNLP--PYLTQEARDLLKKLLKRNAASRLGAGP 340 Query: 432 G-AAEIKRHPFFQGLNW--ALIRWTAPPETP 349 G A E++ HPFF+ +NW L R PP P Sbjct: 341 GDAGEVQAHPFFRHINWEELLARKVEPPFKP 371
>KS6B1_RABIT (P67998) Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1)| (Ribosomal protein S6 kinase I) (S6K) (p70-S6K) Length = 525 Score = 60.1 bits (144), Expect = 5e-09 Identities = 33/91 (36%), Positives = 51/91 (56%), Gaps = 3/91 (3%) Frame = -2 Query: 612 LYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGSRK 433 +Y++L G PF G +T+ ++ L P P ++ +ARDL++ LL + RLG+ Sbjct: 283 MYDMLTGAPPFTGENRKKTIDKILKCKLNLP--PYLTQEARDLLKKLLKRNAASRLGAGP 340 Query: 432 G-AAEIKRHPFFQGLNW--ALIRWTAPPETP 349 G A E++ HPFF+ +NW L R PP P Sbjct: 341 GDAGEVQAHPFFRHINWEELLARKVEPPFKP 371
>KS6B1_MOUSE (Q8BSK8) Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1)| (Ribosomal protein S6 kinase I) (S6K) (p70-S6K) Length = 525 Score = 60.1 bits (144), Expect = 5e-09 Identities = 33/91 (36%), Positives = 51/91 (56%), Gaps = 3/91 (3%) Frame = -2 Query: 612 LYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGSRK 433 +Y++L G PF G +T+ ++ L P P ++ +ARDL++ LL + RLG+ Sbjct: 283 MYDMLTGAPPFTGENRKKTIDKILKCKLNLP--PYLTQEARDLLKKLLKRNAASRLGAGP 340 Query: 432 G-AAEIKRHPFFQGLNW--ALIRWTAPPETP 349 G A E++ HPFF+ +NW L R PP P Sbjct: 341 GDAGEVQAHPFFRHINWEELLARKVEPPFKP 371
>KS6B1_HUMAN (P23443) Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1)| (Ribosomal protein S6 kinase I) (S6K) (S6K1) (70 kDa ribosomal protein S6 kinase 1) (p70 S6 kinase alpha) (p70(S6K)-alpha) (p70-S6K) (p70-alpha) Length = 525 Score = 60.1 bits (144), Expect = 5e-09 Identities = 33/91 (36%), Positives = 51/91 (56%), Gaps = 3/91 (3%) Frame = -2 Query: 612 LYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGSRK 433 +Y++L G PF G +T+ ++ L P P ++ +ARDL++ LL + RLG+ Sbjct: 283 MYDMLTGAPPFTGENRKKTIDKILKCKLNLP--PYLTQEARDLLKKLLKRNAASRLGAGP 340 Query: 432 G-AAEIKRHPFFQGLNW--ALIRWTAPPETP 349 G A E++ HPFF+ +NW L R PP P Sbjct: 341 GDAGEVQAHPFFRHINWEELLARKVEPPFKP 371
>KPCB_RAT (P68403) Protein kinase C beta type (EC 2.7.11.13) (PKC-beta)| (PKC-B) Length = 670 Score = 60.1 bits (144), Expect = 5e-09 Identities = 32/95 (33%), Positives = 53/95 (55%), Gaps = 3/95 (3%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLG- 442 + LYE+L G+ PF G DE +++ + +P S +S +A + +GL+ K P RLG Sbjct: 528 VLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKS--MSKEAVAICKGLMTKHPGKRLGC 585 Query: 441 SRKGAAEIKRHPFFQGLNWALI--RWTAPPETPKS 343 +G +IK H FF+ ++W + + PP PK+ Sbjct: 586 GPEGERDIKEHAFFRYIDWEKLERKEIQPPYKPKA 620
>KPCB_HUMAN (P05771) Protein kinase C beta type (EC 2.7.11.13) (PKC-beta)| (PKC-B) Length = 670 Score = 60.1 bits (144), Expect = 5e-09 Identities = 32/95 (33%), Positives = 53/95 (55%), Gaps = 3/95 (3%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLG- 442 + LYE+L G+ PF G DE +++ + +P S +S +A + +GL+ K P RLG Sbjct: 528 VLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKS--MSKEAVAICKGLMTKHPGKRLGC 585 Query: 441 SRKGAAEIKRHPFFQGLNWALI--RWTAPPETPKS 343 +G +IK H FF+ ++W + + PP PK+ Sbjct: 586 GPEGERDIKEHAFFRYIDWEKLERKEIQPPYKPKA 620
>KPCB_MOUSE (P68404) Protein kinase C beta type (EC 2.7.11.13) (PKC-beta)| (PKC-B) Length = 672 Score = 60.1 bits (144), Expect = 5e-09 Identities = 32/95 (33%), Positives = 53/95 (55%), Gaps = 3/95 (3%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLG- 442 + LYE+L G+ PF G DE +++ + +P S +S +A + +GL+ K P RLG Sbjct: 528 VLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKS--MSKEAVAICKGLMTKHPGKRLGC 585 Query: 441 SRKGAAEIKRHPFFQGLNWALI--RWTAPPETPKS 343 +G +IK H FF+ ++W + + PP PK+ Sbjct: 586 GPEGERDIKEHAFFRYIDWEKLERKEIQPPYKPKA 620
>KPCB_BOVIN (P05126) Protein kinase C beta type (EC 2.7.11.13) (PKC-beta)| (PKC-B) Length = 672 Score = 60.1 bits (144), Expect = 5e-09 Identities = 32/95 (33%), Positives = 53/95 (55%), Gaps = 3/95 (3%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLG- 442 + LYE+L G+ PF G DE +++ + +P S +S +A + +GL+ K P RLG Sbjct: 528 VLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKS--MSKEAVAICKGLITKHPGKRLGC 585 Query: 441 SRKGAAEIKRHPFFQGLNWALI--RWTAPPETPKS 343 +G +IK H FF+ ++W + + PP PK+ Sbjct: 586 GPEGERDIKEHAFFRYIDWEKLERKEIQPPYKPKA 620
>SCH9_YEAST (P11792) Serine/threonine-protein kinase SCH9 (EC 2.7.11.1)| Length = 823 Score = 59.7 bits (143), Expect = 7e-09 Identities = 29/100 (29%), Positives = 51/100 (51%), Gaps = 2/100 (2%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 + ++E+ G +PF N + + +KFP +S + R ++GLL + P+HRLG+ Sbjct: 599 VLIFEMCCGWSPFFAENNQKMYQKIAFGKVKFPRD-VLSQEGRSFVKGLLNRNPKHRLGA 657 Query: 438 RKGAAEIKRHPFFQGLNWALIRW--TAPPETPKSIVEAST 325 E++ HPFF ++W ++ PP P + E T Sbjct: 658 IDDGRELRAHPFFADIDWEALKQKKIPPPFKPHLVSETDT 697
>KPCA_RAT (P05696) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 59.7 bits (143), Expect = 7e-09 Identities = 31/94 (32%), Positives = 52/94 (55%), Gaps = 3/94 (3%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLG- 442 + LYE+L G+ PF G DE +++ + +P S +S +A + +GL+ K P RLG Sbjct: 525 VLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKS--LSKEAVSICKGLMTKHPAKRLGC 582 Query: 441 SRKGAAEIKRHPFFQGLNWALI--RWTAPPETPK 346 +G +++ H FF+ ++W + R PP PK Sbjct: 583 GPEGERDVREHAFFRRIDWEKLENREIQPPFKPK 616
>KPCA_RABIT (P10102) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 59.7 bits (143), Expect = 7e-09 Identities = 31/94 (32%), Positives = 52/94 (55%), Gaps = 3/94 (3%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLG- 442 + LYE+L G+ PF G DE +++ + +P S +S +A + +GL+ K P RLG Sbjct: 525 VLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKS--LSKEAVSICKGLMTKHPAKRLGC 582 Query: 441 SRKGAAEIKRHPFFQGLNWALI--RWTAPPETPK 346 +G +++ H FF+ ++W + R PP PK Sbjct: 583 GPEGERDVREHAFFRRIDWEKLENREIQPPFKPK 616
>KPCA_HUMAN (P17252) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 59.7 bits (143), Expect = 7e-09 Identities = 31/94 (32%), Positives = 52/94 (55%), Gaps = 3/94 (3%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLG- 442 + LYE+L G+ PF G DE +++ + +P S +S +A + +GL+ K P RLG Sbjct: 525 VLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKS--LSKEAVSICKGLMTKHPAKRLGC 582 Query: 441 SRKGAAEIKRHPFFQGLNWALI--RWTAPPETPK 346 +G +++ H FF+ ++W + R PP PK Sbjct: 583 GPEGERDVREHAFFRRIDWEKLENREIQPPFKPK 616
>KS6A6_HUMAN (Q9UK32) Ribosomal protein S6 kinase alpha-6 (EC 2.7.11.1)| (S6K-alpha 6) (90 kDa ribosomal protein S6 kinase 6) (p90-RSK 6) (Ribosomal S6 kinase 4) (RSK-4) (pp90RSK4) Length = 745 Score = 59.3 bits (142), Expect = 9e-09 Identities = 34/94 (36%), Positives = 53/94 (56%), Gaps = 2/94 (2%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 + ++E+L G PF+G +ET+ ++ L P +S +A+ L+R L + P +RLGS Sbjct: 261 VLMFEMLTGTLPFQGKDRNETMNMILKAKLGMPQ--FLSAEAQSLLRMLFKRNPANRLGS 318 Query: 438 RKGAAEIKRHPFFQGLNWALI--RWTAPPETPKS 343 +G EIKRH FF ++W + R PP P S Sbjct: 319 -EGVEEIKRHLFFANIDWDKLYKREVQPPFKPAS 351
>KPCB_RABIT (P05772) Protein kinase C beta type (EC 2.7.11.13) (PKC-beta)| (PKC-B) Length = 670 Score = 59.3 bits (142), Expect = 9e-09 Identities = 32/95 (33%), Positives = 53/95 (55%), Gaps = 3/95 (3%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLG- 442 + LYE+L G+ PF G DE +++ + +P S +S +A + +GL+ K P RLG Sbjct: 528 VLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKS--MSKEAVAICKGLMTKHPGKRLGC 585 Query: 441 SRKGAAEIKRHPFFQGLNWALI--RWTAPPETPKS 343 +G +IK H FF+ ++W + + PP PK+ Sbjct: 586 GPEGERDIKDHAFFRYIDWEKLERKEIQPPYKPKA 620
>KPCA_BOVIN (P04409) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 59.3 bits (142), Expect = 9e-09 Identities = 31/94 (32%), Positives = 52/94 (55%), Gaps = 3/94 (3%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLG- 442 + LYE+L G+ PF G DE +++ + +P S +S +A + +GL+ K P RLG Sbjct: 525 VLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKS--LSKEAVSICKGLMTKHPGKRLGC 582 Query: 441 SRKGAAEIKRHPFFQGLNWALI--RWTAPPETPK 346 +G +++ H FF+ ++W + R PP PK Sbjct: 583 GPEGERDVREHAFFRRIDWEKLENREIQPPFKPK 616
>GRK2_CAEEL (Q09639) G protein-coupled receptor kinase 2 (EC 2.7.11.16)| Length = 707 Score = 58.9 bits (141), Expect = 1e-08 Identities = 37/102 (36%), Positives = 56/102 (54%), Gaps = 7/102 (6%) Frame = -2 Query: 612 LYELLYGKTPFR---GPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLG 442 LY+LL G +PFR +E ++Q ++ P+ +S RDL+ GLL ++ RLG Sbjct: 382 LYKLLKGHSPFRQHKSKDKNEIDKMTLTQDIELPNE-GLSKDCRDLLEGLLKRDVPDRLG 440 Query: 441 SR-KGAAEIKRHPFFQGLNWALI---RWTAPPETPKSIVEAS 328 R KG E+K HPFF+ ++W + R T P P+ V A+ Sbjct: 441 CRGKGPTEVKEHPFFKDVDWQTVYLRRMTPPLIPPRGEVNAA 482
>MRCKB_RAT (Q7TT49) Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1)| (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta) Length = 1713 Score = 58.9 bits (141), Expect = 1e-08 Identities = 36/93 (38%), Positives = 53/93 (56%), Gaps = 3/93 (3%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVS--QGLKFPDSPA-VSYQARDLIRGLLVKEPEHR 448 + +YE+LYG+TPF ET +++ + +FP VS +A+DLI+ L+ E R Sbjct: 269 VCMYEMLYGETPFYAESLVETYGKIMNHEERFQFPSHVTDVSEEAKDLIQRLICSR-ERR 327 Query: 447 LGSRKGAAEIKRHPFFQGLNWALIRWTAPPETP 349 LG + G + K+H FF+GLNW IR P P Sbjct: 328 LG-QNGIEDFKKHAFFEGLNWENIRNLEAPYIP 359
>MRCKB_MOUSE (Q7TT50) Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1)| (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta) Length = 1713 Score = 58.9 bits (141), Expect = 1e-08 Identities = 36/93 (38%), Positives = 53/93 (56%), Gaps = 3/93 (3%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVS--QGLKFPDSPA-VSYQARDLIRGLLVKEPEHR 448 + +YE+LYG+TPF ET +++ + +FP VS +A+DLI+ L+ E R Sbjct: 269 VCMYEMLYGETPFYAESLVETYGKIMNHEERFQFPSHVTDVSEEAKDLIQRLICSR-ERR 327 Query: 447 LGSRKGAAEIKRHPFFQGLNWALIRWTAPPETP 349 LG + G + K+H FF+GLNW IR P P Sbjct: 328 LG-QNGIEDFKKHAFFEGLNWENIRNLEAPYIP 359
>SGK3_HUMAN (Q96BR1) Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 3) (Serum/glucocorticoid-regulated kinase-like) Length = 496 Score = 58.9 bits (141), Expect = 1e-08 Identities = 33/86 (38%), Positives = 50/86 (58%), Gaps = 1/86 (1%) Frame = -2 Query: 612 LYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGSRK 433 LYE+LYG PF E N++ + L P VS A ++ LL K+ ++RLG+++ Sbjct: 351 LYEMLYGLPPFYCRDVAEMYDNILHKPLSL--RPGVSLTAWSILEELLEKDRQNRLGAKE 408 Query: 432 GAAEIKRHPFFQGLNWA-LIRWTAPP 358 EI+ HPFF+ L+WA L++ PP Sbjct: 409 DFLEIQNHPFFESLSWADLVQKKIPP 434
>MRCKG_MOUSE (Q80UW5) Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1)| (CDC42-binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma Length = 1551 Score = 58.9 bits (141), Expect = 1e-08 Identities = 36/91 (39%), Positives = 54/91 (59%), Gaps = 3/91 (3%) Frame = -2 Query: 609 YELLYGKTPFRGPGNDETLTNVVSQG--LKFP-DSPAVSYQARDLIRGLLVKEPEHRLGS 439 YELL+G+TPF ET +++ L+FP D V A+DLIR LL ++ E RLG Sbjct: 267 YELLFGETPFYAESLVETYGKIMNHEDHLQFPADVTDVPASAQDLIRQLLCRQ-EERLG- 324 Query: 438 RKGAAEIKRHPFFQGLNWALIRWTAPPETPK 346 R G + ++HPFF+G++W + + P P+ Sbjct: 325 RGGLDDFRKHPFFEGVDWERLATSTAPYIPE 355
>KS6A1_HUMAN (Q15418) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 735 Score = 58.9 bits (141), Expect = 1e-08 Identities = 34/93 (36%), Positives = 52/93 (55%), Gaps = 3/93 (3%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 + ++E+L G PF+G ET+T ++ L P +S +A+ L+R L + P +RLGS Sbjct: 250 VLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQ--FLSTEAQSLLRALFKRNPANRLGS 307 Query: 438 -RKGAAEIKRHPFFQGLNWALI--RWTAPPETP 349 GA EIKRH F+ ++W + R PP P Sbjct: 308 GPDGAEEIKRHVFYSTIDWNKLYRREIKPPFKP 340
>MRCKB_HUMAN (Q9Y5S2) Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1)| (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta) Length = 1711 Score = 58.9 bits (141), Expect = 1e-08 Identities = 36/93 (38%), Positives = 53/93 (56%), Gaps = 3/93 (3%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVS--QGLKFPDSPA-VSYQARDLIRGLLVKEPEHR 448 + +YE+LYG+TPF ET +++ + +FP VS +A+DLI+ L+ E R Sbjct: 269 VCMYEMLYGETPFYAESLVETYGKIMNHEERFQFPSHVTDVSEEAKDLIQRLICSR-ERR 327 Query: 447 LGSRKGAAEIKRHPFFQGLNWALIRWTAPPETP 349 LG + G + K+H FF+GLNW IR P P Sbjct: 328 LG-QNGIEDFKKHAFFEGLNWENIRNLEAPYIP 359
>KPC1_APLCA (Q16974) Calcium-dependent protein kinase C (EC 2.7.11.13) (APL I)| Length = 649 Score = 58.5 bits (140), Expect = 1e-08 Identities = 34/94 (36%), Positives = 49/94 (52%), Gaps = 3/94 (3%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLG- 442 + LYE+L G+ PF G +E T++ + +P A+S +A L +GLL K P RLG Sbjct: 507 VLLYEMLAGQPPFDGEDEEELFTSITDHNVSYP--KALSREAVSLCKGLLTKTPAKRLGC 564 Query: 441 SRKGAAEIKRHPFFQGLNWALI--RWTAPPETPK 346 G +IK FF+ + W I R PP P+ Sbjct: 565 GPNGERDIKDRAFFRPIQWERIELREVQPPYKPR 598
>KS6B2_MOUSE (Q9Z1M4) Ribosomal protein S6 kinase beta-2 (EC 2.7.11.1) (S6K-beta| 2) (70 kDa ribosomal protein S6 kinase 2) (p70-S6KB) (p70 ribosomal S6 kinase beta) (p70 S6Kbeta) (S6K2) Length = 485 Score = 58.5 bits (140), Expect = 1e-08 Identities = 32/91 (35%), Positives = 49/91 (53%), Gaps = 3/91 (3%) Frame = -2 Query: 612 LYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGSRK 433 +Y++L G PF +T+ ++ L P P ++ ARDL + L + P R+G Sbjct: 259 MYDMLTGSPPFTAENRKKTMDKIIKGKLVLP--PYLTPDARDLAKKFLKRNPTQRIGGGL 316 Query: 432 G-AAEIKRHPFFQGLNW--ALIRWTAPPETP 349 G AA+++RHPFF+ +NW L R PP P Sbjct: 317 GDAADVQRHPFFRHINWDDLLARRVDPPFRP 347
>KS6A1_RAT (Q63531) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 735 Score = 58.5 bits (140), Expect = 1e-08 Identities = 34/93 (36%), Positives = 52/93 (55%), Gaps = 3/93 (3%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 + ++E+L G PF+G ET+T ++ L P +S +A+ L+R L + P +RLGS Sbjct: 250 VLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQ--FLSTEAQSLLRALFKRNPANRLGS 307 Query: 438 -RKGAAEIKRHPFFQGLNWALI--RWTAPPETP 349 GA EIKRH F+ ++W + R PP P Sbjct: 308 GPDGAEEIKRHIFYSTIDWNKLYRREIKPPFKP 340
>ROCK2_MOUSE (P70336) Rho-associated protein kinase 2 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 2) (p164 ROCK-2) Length = 1388 Score = 58.2 bits (139), Expect = 2e-08 Identities = 38/95 (40%), Positives = 52/95 (54%), Gaps = 4/95 (4%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQ--GLKFPDSPAVSYQARDLIRGLLVKEPEHRL 445 +FL+E+L G TPF T + ++ L FP+ +S A++LI L + E RL Sbjct: 282 VFLFEMLVGDTPFYADSLVGTYSKIMDHKNSLCFPEDTEISKHAKNLICAFLT-DREVRL 340 Query: 444 GSRKGAAEIKRHPFFQG--LNWALIRWTAPPETPK 346 G R G EIK+HPFF+ NW IR TA P P+ Sbjct: 341 G-RNGVEEIKQHPFFKNDQWNWDNIRETAAPVVPE 374
>ROCK2_BOVIN (Q28021) Rho-associated protein kinase 2 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 2) (p164 ROCK-2) Length = 1388 Score = 58.2 bits (139), Expect = 2e-08 Identities = 38/95 (40%), Positives = 52/95 (54%), Gaps = 4/95 (4%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQ--GLKFPDSPAVSYQARDLIRGLLVKEPEHRL 445 +FL+E+L G TPF T + ++ L FP+ +S A++LI L + E RL Sbjct: 282 VFLFEMLVGDTPFYADSLVGTYSKIMDHKNSLCFPEDAEISKHAKNLICAFLT-DREVRL 340 Query: 444 GSRKGAAEIKRHPFFQG--LNWALIRWTAPPETPK 346 G R G EIK+HPFF+ NW IR TA P P+ Sbjct: 341 G-RNGVEEIKQHPFFKNDQWNWDNIRETAAPVVPE 374
>SGK1_HUMAN (O00141) Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 1) Length = 431 Score = 58.2 bits (139), Expect = 2e-08 Identities = 33/90 (36%), Positives = 48/90 (53%), Gaps = 2/90 (2%) Frame = -2 Query: 612 LYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGSRK 433 LYE+LYG PF E N++++ L+ P ++ AR L+ GLL K+ RLG++ Sbjct: 287 LYEMLYGLPPFYSRNTAEMYDNILNKPLQL--KPNITNSARHLLEGLLQKDRTKRLGAKD 344 Query: 432 GAAEIKRHPFFQGLNW--ALIRWTAPPETP 349 EIK H FF +NW + + PP P Sbjct: 345 DFMEIKSHVFFSLINWDDLINKKITPPFNP 374
>MAST3_HUMAN (O60307) Microtubule-associated serine/threonine-protein kinase 3| (EC 2.7.11.1) Length = 1309 Score = 58.2 bits (139), Expect = 2e-08 Identities = 34/80 (42%), Positives = 46/80 (57%), Gaps = 1/80 (1%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSP-AVSYQARDLIRGLLVKEPEHRLG 442 + LYE L G PF G +E VVS + +P+ A+ A+DLI LL + P RLG Sbjct: 568 VVLYEFLVGCVPFFGDTPEELFGQVVSDEIMWPEGDEALPADAQDLITRLLRQSPLDRLG 627 Query: 441 SRKGAAEIKRHPFFQGLNWA 382 + G E+K+HPFF L+WA Sbjct: 628 TG-GTHEVKQHPFFLALDWA 646
>KPCD_HUMAN (Q05655) Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta)| Length = 676 Score = 57.8 bits (138), Expect = 3e-08 Identities = 32/93 (34%), Positives = 50/93 (53%), Gaps = 2/93 (2%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 + LYE+L G++PF G DE ++ +P ++ +++D++ L +EP RLG Sbjct: 536 VLLYEMLIGQSPFHGDDEDELFESIRVDTPHYP--RWITKESKDILEKLFEREPTKRLGM 593 Query: 438 RKGAAEIKRHPFFQGLNWALI--RWTAPPETPK 346 IK HPFF+ +NW L+ R PP PK Sbjct: 594 ---TGNIKIHPFFKTINWTLLEKRRLEPPFRPK 623
>YPK1_YEAST (P12688) Serine/threonine-protein kinase YPK1 (EC 2.7.11.1)| Length = 680 Score = 57.8 bits (138), Expect = 3e-08 Identities = 34/92 (36%), Positives = 49/92 (53%), Gaps = 2/92 (2%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 + LYE+L G P+ + ++ + L FPD A+DL+ GLL ++P RLG Sbjct: 533 VLLYEMLTGLPPYYDEDVPKMYKKILQEPLVFPDG--FDRDAKDLLIGLLSRDPTRRLGY 590 Query: 438 RKGAAEIKRHPFFQGLNW--ALIRWTAPPETP 349 GA EI+ HPFF L+W L++ PP P Sbjct: 591 N-GADEIRNHPFFSQLSWKRLLMKGYIPPYKP 621
>MAST2_MOUSE (Q60592) Microtubule-associated serine/threonine-protein kinase 2| (EC 2.7.11.1) Length = 1734 Score = 57.8 bits (138), Expect = 3e-08 Identities = 33/79 (41%), Positives = 45/79 (56%), Gaps = 1/79 (1%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSP-AVSYQARDLIRGLLVKEPEHRLG 442 I LYE L G PF G +E V+S + +P+ A+ A+DL LL + P RLG Sbjct: 654 IILYEFLVGCVPFFGDTPEELFGQVISDEIVWPEGDDALPPDAQDLTSKLLHQNPLERLG 713 Query: 441 SRKGAAEIKRHPFFQGLNW 385 + A E+K+HPFF GL+W Sbjct: 714 T-SSAYEVKQHPFFMGLDW 731
>SGK1_MOUSE (Q9WVC6) Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 1) Length = 431 Score = 57.8 bits (138), Expect = 3e-08 Identities = 33/90 (36%), Positives = 48/90 (53%), Gaps = 2/90 (2%) Frame = -2 Query: 612 LYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGSRK 433 LYE+LYG PF E N++++ L+ P ++ AR L+ GLL K+ RLG++ Sbjct: 287 LYEMLYGLPPFYSRNTAEMYDNILNKPLQL--KPNITNSARHLLEGLLQKDRTKRLGAKD 344 Query: 432 GAAEIKRHPFFQGLNW--ALIRWTAPPETP 349 EIK H FF +NW + + PP P Sbjct: 345 DFMEIKSHIFFSLINWDDLINKKITPPFNP 374
>PCK1_SCHPO (P36582) Protein kinase C-like 1 (EC 2.7.11.13)| Length = 988 Score = 57.8 bits (138), Expect = 3e-08 Identities = 31/80 (38%), Positives = 47/80 (58%), Gaps = 2/80 (2%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFP-DSPAVSYQARDLIRGLLVKEPEHRLG 442 + +Y++L G++PF+G +E ++S FP + PA A L+RGLL ++P RLG Sbjct: 852 VLMYQMLLGQSPFKGEDEEEIFDAILSDEPLFPINMPA---DAVSLLRGLLTRDPNQRLG 908 Query: 441 S-RKGAAEIKRHPFFQGLNW 385 S K A E+ HPFF + W Sbjct: 909 SGPKDANEVMAHPFFASIVW 928
>KS6A5_CHICK (Q5F3L1) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1)| Length = 789 Score = 57.8 bits (138), Expect = 3e-08 Identities = 32/81 (39%), Positives = 48/81 (59%), Gaps = 3/81 (3%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKF--PDSPAVSYQARDLIRGLLVKEPEHRL 445 + +YELL G +PF G + + + LK P +S ++D+I+ LL+K+P+ RL Sbjct: 233 VLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSALSKDIIQRLLMKDPKKRL 292 Query: 444 G-SRKGAAEIKRHPFFQGLNW 385 G A EIK+HPFFQ +NW Sbjct: 293 GCGPTDADEIKQHPFFQNINW 313
>CTRO_MOUSE (P49025) Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK)| (Rho-interacting, serine/threonine-protein kinase 21) Length = 2055 Score = 57.4 bits (137), Expect = 3e-08 Identities = 34/92 (36%), Positives = 49/92 (53%), Gaps = 2/92 (2%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVS--QGLKFPDSPAVSYQARDLIRGLLVKEPEHRL 445 + YE++YGKTPF + T N+++ + LKFPD P VS + DL++ LL + E Sbjct: 290 VVAYEMVYGKTPFTEGTSARTFNNIMNFQRFLKFPDDPKVSSELLDLLQSLLCVQKE--- 346 Query: 444 GSRKGAAEIKRHPFFQGLNWALIRWTAPPETP 349 R + HPFF +W IR + PP P Sbjct: 347 --RLKFEGLCCHPFFARTDWNNIRNSPPPFVP 376
>YPK2_YEAST (P18961) Serine/threonine-protein kinase YPK2/YKR2 (EC 2.7.11.1)| Length = 677 Score = 57.4 bits (137), Expect = 3e-08 Identities = 38/113 (33%), Positives = 58/113 (51%), Gaps = 6/113 (5%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDS--PAVSYQARDLIRGLLVKEPEHRL 445 I LYE++ G P+ ++ Q L FPD PA A+DL+ GLL ++P RL Sbjct: 530 ILLYEMMTGLPPYYDENVPVMYKKILQQPLLFPDGFDPA----AKDLLIGLLSRDPSRRL 585 Query: 444 GSRKGAAEIKRHPFFQGLNW--ALIRWTAPPETP--KSIVEASTLTVAVARKK 298 G G EI+ HPFF+ ++W L++ PP P KS ++ + ++K Sbjct: 586 GVN-GTDEIRNHPFFKDISWKKLLLKGYIPPYKPIVKSEIDTANFDQEFTKEK 637
>SGK1_RABIT (Q9XT18) Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 1) Length = 431 Score = 57.4 bits (137), Expect = 3e-08 Identities = 32/90 (35%), Positives = 48/90 (53%), Gaps = 2/90 (2%) Frame = -2 Query: 612 LYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGSRK 433 LYE+LYG PF E N++++ L+ P ++ AR L+ GLL K+ RLG++ Sbjct: 287 LYEMLYGLPPFYSRNTAEMYDNILNKPLQL--KPNITNSARHLLEGLLQKDRTKRLGAKD 344 Query: 432 GAAEIKRHPFFQGLNW--ALIRWTAPPETP 349 EI+ H FF +NW + + PP P Sbjct: 345 DFMEIRNHVFFSLINWDDLINKKITPPFNP 374
>SGK2_MOUSE (Q9QZS5) Serine/threonine-protein kinase Sgk2 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 2) Length = 367 Score = 57.4 bits (137), Expect = 3e-08 Identities = 30/76 (39%), Positives = 44/76 (57%) Frame = -2 Query: 612 LYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGSRK 433 LYE+L+G PF + N++ Q L+ P V+ A DL++GLL K+ RLGS++ Sbjct: 224 LYEMLHGLPPFFNTDVAQMYENILHQPLQIPGGRTVA--ACDLLQGLLHKDQRQRLGSKE 281 Query: 432 GAAEIKRHPFFQGLNW 385 +IK H FF +NW Sbjct: 282 DFLDIKNHMFFSPINW 297
>SGK2_RAT (Q8R4U9) Serine/threonine-protein kinase Sgk2 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 2) (Fragment) Length = 302 Score = 57.4 bits (137), Expect = 3e-08 Identities = 30/76 (39%), Positives = 44/76 (57%) Frame = -2 Query: 612 LYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGSRK 433 LYE+L+G PF + N++ Q L+ P V+ A DL++GLL K+ RLGS++ Sbjct: 207 LYEMLHGLPPFFNTDVAQMYENILHQPLQIPGGRTVA--ACDLLQGLLHKDQRQRLGSKE 264 Query: 432 GAAEIKRHPFFQGLNW 385 +IK H FF +NW Sbjct: 265 DFLDIKNHMFFSPINW 280
>ROCK1_RAT (Q63644) Rho-associated protein kinase 1 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (p150 RhoA-binding kinase ROK beta) (Liver regeneration-related protein LRRG199) Length = 1369 Score = 57.0 bits (136), Expect = 4e-08 Identities = 38/94 (40%), Positives = 51/94 (54%), Gaps = 4/94 (4%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQ--GLKFPDSPAVSYQARDLIRGLLVKEPEHRL 445 +FLYE+L G TPF T + +++ L FPD +S +A++LI L + E RL Sbjct: 266 VFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFPDDNDISKEAKNLICAFLT-DREVRL 324 Query: 444 GSRKGAAEIKRHPFFQGLNWA--LIRWTAPPETP 349 G R G EIKRH FF+ WA +R T P P Sbjct: 325 G-RNGVEEIKRHLFFKNDQWAWETLRDTVAPVVP 357
>PKN3_HUMAN (Q6P5Z2) Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein| kinase PKN-beta) (Protein-kinase C-related kinase 3) Length = 889 Score = 57.0 bits (136), Expect = 4e-08 Identities = 36/93 (38%), Positives = 49/93 (52%), Gaps = 3/93 (3%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 + LYE+L G+ PF G +E +V+ +P +S Q + I+ LL K PE RLG+ Sbjct: 747 VLLYEMLVGECPFPGDTEEEVFDCIVNMDAPYPG--FLSVQGLEFIQKLLQKCPEKRLGA 804 Query: 438 -RKGAAEIKRHPFFQGLNW--ALIRWTAPPETP 349 + A EIK PFF+ NW L R PP P Sbjct: 805 GEQDAEEIKVQPFFRTTNWQALLARTIQPPFVP 837
>KAPC_YEAST (P05986) cAMP-dependent protein kinase type 3 (EC 2.7.11.11) (PKA| 3) Length = 398 Score = 57.0 bits (136), Expect = 4e-08 Identities = 31/93 (33%), Positives = 52/93 (55%), Gaps = 3/93 (3%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 + +YE+L G TPF +T N+++ LKFP P A+DL++ L+ ++ RLG+ Sbjct: 271 VLIYEMLAGYTPFYNSNTMKTYENILNAELKFP--PFFHPDAQDLLKKLITRDLSERLGN 328 Query: 438 -RKGAAEIKRHPFFQGLNW--ALIRWTAPPETP 349 + G+ ++K HP+F + W L R+ P P Sbjct: 329 LQNGSEDVKNHPWFNEVIWEKLLARYIETPYEP 361
>RK_HUMAN (Q15835) Rhodopsin kinase precursor (EC 2.7.11.14) (RK) (G| protein-coupled receptor kinase 1) Length = 563 Score = 57.0 bits (136), Expect = 4e-08 Identities = 34/99 (34%), Positives = 51/99 (51%), Gaps = 7/99 (7%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPG----NDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEH 451 + LYE++ + PFR G N E ++S+ +K+PD S ++D LL K+PE Sbjct: 380 VTLYEMIAARGPFRARGEKVENKELKHRIISEPVKYPDK--FSQASKDFCEALLEKDPEK 437 Query: 450 RLGSRKGAAE-IKRHPFFQGLNWALIR--WTAPPETPKS 343 RLG R + ++ HP F+ LNW + PP P S Sbjct: 438 RLGFRDETCDKLRAHPLFKDLNWRQLEAGMLMPPFIPDS 476
>ROCK1_RABIT (O77819) Rho-associated protein kinase 1 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (cAMP-dependent protein kinase ROCK-I) (CePKA) (Corneal epithelial Rho-associated-Ser/Thr kinase 1) (HEB Length = 1354 Score = 57.0 bits (136), Expect = 4e-08 Identities = 38/94 (40%), Positives = 51/94 (54%), Gaps = 4/94 (4%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQ--GLKFPDSPAVSYQARDLIRGLLVKEPEHRL 445 +FLYE+L G TPF T + +++ L FPD +S +A++LI L + E RL Sbjct: 266 VFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFPDDNDISKEAKNLICAFLT-DREVRL 324 Query: 444 GSRKGAAEIKRHPFFQGLNWA--LIRWTAPPETP 349 G R G EIKRH FF+ WA +R T P P Sbjct: 325 G-RNGVEEIKRHLFFKNDQWAWETLRDTVAPVVP 357
>ROCK1_MOUSE (P70335) Rho-associated protein kinase 1 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) Length = 1354 Score = 57.0 bits (136), Expect = 4e-08 Identities = 38/94 (40%), Positives = 51/94 (54%), Gaps = 4/94 (4%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQ--GLKFPDSPAVSYQARDLIRGLLVKEPEHRL 445 +FLYE+L G TPF T + +++ L FPD +S +A++LI L + E RL Sbjct: 266 VFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFPDDNDISKEAKNLICAFLT-DREVRL 324 Query: 444 GSRKGAAEIKRHPFFQGLNWA--LIRWTAPPETP 349 G R G EIKRH FF+ WA +R T P P Sbjct: 325 G-RNGVEEIKRHLFFKNDQWAWETLRDTVAPVVP 357
>ROCK1_HUMAN (Q13464) Rho-associated protein kinase 1 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen) Length = 1354 Score = 57.0 bits (136), Expect = 4e-08 Identities = 38/94 (40%), Positives = 51/94 (54%), Gaps = 4/94 (4%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQ--GLKFPDSPAVSYQARDLIRGLLVKEPEHRL 445 +FLYE+L G TPF T + +++ L FPD +S +A++LI L + E RL Sbjct: 266 VFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFPDDNDISKEAKNLICAFLT-DREVRL 324 Query: 444 GSRKGAAEIKRHPFFQGLNWA--LIRWTAPPETP 349 G R G EIKRH FF+ WA +R T P P Sbjct: 325 G-RNGVEEIKRHLFFKNDQWAWETLRDTVAPVVP 357
>ROCK2_HUMAN (O75116) Rho-associated protein kinase 2 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2) Length = 1388 Score = 56.6 bits (135), Expect = 6e-08 Identities = 37/95 (38%), Positives = 52/95 (54%), Gaps = 4/95 (4%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQ--GLKFPDSPAVSYQARDLIRGLLVKEPEHRL 445 +FLYE+L G TPF T + ++ L FP+ +S A++LI L + E RL Sbjct: 282 VFLYEMLVGDTPFYADSLVGTYSKIMDHKNSLCFPEDAEISKHAKNLICAFLT-DREVRL 340 Query: 444 GSRKGAAEIKRHPFFQG--LNWALIRWTAPPETPK 346 G R G EI++HPFF+ +W IR TA P P+ Sbjct: 341 G-RNGVEEIRQHPFFKNDQWHWDNIRETAAPVVPE 374
>MAST2_HUMAN (Q6P0Q8) Microtubule-associated serine/threonine-protein kinase 2| (EC 2.7.11.1) Length = 1798 Score = 56.6 bits (135), Expect = 6e-08 Identities = 33/79 (41%), Positives = 45/79 (56%), Gaps = 1/79 (1%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSP-AVSYQARDLIRGLLVKEPEHRLG 442 I LYE L G PF G +E V+S + +P+ A+ A+DL LL + P RLG Sbjct: 713 IILYEFLVGCVPFFGDTPEELFGQVISDEIVWPEGDEALPPDAQDLTSKLLHQNPLERLG 772 Query: 441 SRKGAAEIKRHPFFQGLNW 385 + A E+K+HPFF GL+W Sbjct: 773 TGS-AYEVKQHPFFTGLDW 790
>SGK3_MOUSE (Q9ERE3) Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 3) (Serum/glucocorticoid-regulated kinase-like) (Cytokine independent survival kinase) Length = 496 Score = 56.6 bits (135), Expect = 6e-08 Identities = 32/86 (37%), Positives = 48/86 (55%), Gaps = 1/86 (1%) Frame = -2 Query: 612 LYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGSRK 433 LYE+LYG PF E N++ + L P VS A ++ LL K ++RLG+++ Sbjct: 351 LYEMLYGLPPFYCRDVAEMYDNILHKPLNL--RPGVSLTAWSILEELLEKNRQNRLGAKE 408 Query: 432 GAAEIKRHPFFQGLNWA-LIRWTAPP 358 EI+ HPFF+ L+W L++ PP Sbjct: 409 DFLEIQNHPFFESLSWTDLVQKKIPP 434
>CTRO_HUMAN (O14578) Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK)| (Rho-interacting, serine/threonine-protein kinase 21) Length = 2027 Score = 56.6 bits (135), Expect = 6e-08 Identities = 33/92 (35%), Positives = 49/92 (53%), Gaps = 2/92 (2%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVS--QGLKFPDSPAVSYQARDLIRGLLVKEPEHRL 445 + YE++YG++PF + T N+++ + LKFPD P VS DLI+ LL + E Sbjct: 291 VIAYEMIYGRSPFAEGTSARTFNNIMNFQRFLKFPDDPKVSSDFLDLIQSLLCGQKE--- 347 Query: 444 GSRKGAAEIKRHPFFQGLNWALIRWTAPPETP 349 R + HPFF ++W IR + PP P Sbjct: 348 --RLKFEGLCCHPFFSKIDWNNIRNSPPPFVP 377
>SGK2_HUMAN (Q9HBY8) Serine/threonine-protein kinase Sgk2 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 2) Length = 427 Score = 56.6 bits (135), Expect = 6e-08 Identities = 30/76 (39%), Positives = 42/76 (55%) Frame = -2 Query: 612 LYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGSRK 433 LYE+L+G PF + N++ Q L+ P V+ A DL++ LL K+ RLGS+ Sbjct: 284 LYEMLHGLPPFYSQDVSQMYENILHQPLQIPGGRTVA--ACDLLQSLLHKDQRQRLGSKA 341 Query: 432 GAAEIKRHPFFQGLNW 385 EIK H FF +NW Sbjct: 342 DFLEIKNHVFFSPINW 357
>KPCD_MOUSE (P28867) Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta)| Length = 674 Score = 56.6 bits (135), Expect = 6e-08 Identities = 30/93 (32%), Positives = 52/93 (55%), Gaps = 2/93 (2%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 + LYE+L G++PF G DE ++ +P ++ +++D++ L ++P+ RLG Sbjct: 534 VLLYEMLIGQSPFHGDDEDELFESIRVDTPHYP--RWITKESKDIMEKLFERDPDKRLGV 591 Query: 438 RKGAAEIKRHPFFQGLNWALI--RWTAPPETPK 346 I+ HPFF+ +NW+L+ R PP PK Sbjct: 592 ---TGNIRIHPFFKTINWSLLEKRKVEPPFKPK 621
>ST38L_HUMAN (Q9Y2H1) Serine/threonine-protein kinase 38-like (EC 2.7.11.1)| (NDR2 protein kinase) (Nuclear Dbf2-related kinase 2) Length = 464 Score = 56.2 bits (134), Expect = 7e-08 Identities = 38/101 (37%), Positives = 56/101 (55%), Gaps = 4/101 (3%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVS--QGLKFPDSPAVSYQARDLIRGLLVKEPEHRL 445 + +YE+L G PF ET V++ + L FP +S +A+DLI + + E+R+ Sbjct: 311 VIMYEMLIGYPPFCSETPQETYRKVMNWKETLVFPPEVPISEKAKDLILRFCI-DSENRI 369 Query: 444 GSRKGAAEIKRHPFFQGLNWALIRW--TAPPETPKSIVEAS 328 G+ G EIK HPFF+G++W IR A P KSI + S Sbjct: 370 GN-SGVEEIKGHPFFEGVDWEHIRERPAAIPIEIKSIDDTS 409
>KPCT_HUMAN (Q04759) Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)| Length = 706 Score = 56.2 bits (134), Expect = 7e-08 Identities = 32/93 (34%), Positives = 52/93 (55%), Gaps = 2/93 (2%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 + LYE+L G++PF G +E ++ +P + +A+DL+ L V+EPE RLG Sbjct: 567 VLLYEMLIGQSPFHGQDEEELFHSIRMDNPFYPRW--LEKEAKDLLVKLFVREPEKRLGV 624 Query: 438 RKGAAEIKRHPFFQGLNWALI--RWTAPPETPK 346 R +I++HP F+ +NW + + PP PK Sbjct: 625 R---GDIRQHPLFREINWEELERKEIDPPFRPK 654
>KS6A2_MOUSE (Q9WUT3) Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1)| (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (Protein-tyrosine kinase Mpk-9) (MAP kinase-activated protein kinase 1c) (M Length = 733 Score = 56.2 bits (134), Expect = 7e-08 Identities = 29/79 (36%), Positives = 46/79 (58%), Gaps = 1/79 (1%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 + ++E+L G PF+G ET+ ++ L P +S +A+ L+R L + P +RLG+ Sbjct: 247 VLMFEMLTGSLPFQGKDRKETMALILKAKLGMPQF--LSAEAQSLLRALFKRNPCNRLGA 304 Query: 438 R-KGAAEIKRHPFFQGLNW 385 G EIKRHPFF ++W Sbjct: 305 GVDGVEEIKRHPFFVTIDW 323
>RK_BOVIN (P28327) Rhodopsin kinase precursor (EC 2.7.11.14) (RK) (G| protein-coupled receptor kinase 1) Length = 561 Score = 56.2 bits (134), Expect = 7e-08 Identities = 35/101 (34%), Positives = 53/101 (52%), Gaps = 9/101 (8%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPG----NDETLTNVVSQGLKFPD--SPAVSYQARDLIRGLLVKEP 457 + LYE++ + PFR G N E V+ Q + +PD SPA ++D LL K+P Sbjct: 377 VTLYEMIAARGPFRARGEKVENKELKQRVLEQAVTYPDKFSPA----SKDFCEALLQKDP 432 Query: 456 EHRLGSRKGAAE-IKRHPFFQGLNWALIR--WTAPPETPKS 343 E RLG R G+ + ++ HP F+ ++W + PP P S Sbjct: 433 EKRLGFRDGSCDGLRTHPLFRDISWRQLEAGMLTPPFVPDS 473
>ST38L_MOUSE (Q7TSE6) Serine/threonine-protein kinase 38-like (EC 2.7.11.1)| (NDR2 protein kinase) (Nuclear Dbf2-related kinase 2) Length = 464 Score = 55.8 bits (133), Expect = 1e-07 Identities = 34/84 (40%), Positives = 48/84 (57%), Gaps = 2/84 (2%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVS--QGLKFPDSPAVSYQARDLIRGLLVKEPEHRL 445 + +YE+L G PF ET V+S + L FP VS +A+DLI + E+R+ Sbjct: 311 VIMYEMLIGFPPFCSETPQETYRKVMSWKETLAFPPEVPVSEKAKDLILRFCT-DSENRI 369 Query: 444 GSRKGAAEIKRHPFFQGLNWALIR 373 G+ G EIK HPFF+G++W IR Sbjct: 370 GNG-GVEEIKGHPFFEGVDWGHIR 392
>KGP1B_MOUSE (Q9Z0Z0) cGMP-dependent protein kinase 1, beta isozyme (EC| 2.7.11.12) (cGK 1 beta) (cGKI-beta) Length = 686 Score = 55.8 bits (133), Expect = 1e-07 Identities = 34/94 (36%), Positives = 52/94 (55%), Gaps = 4/94 (4%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPA-VSYQARDLIRGLLVKEPEHRLG 442 I +YELL G PF GP +T N++ +G+ + P ++ A +LI+ L P RLG Sbjct: 561 ILMYELLTGSPPFSGPDPMKTY-NIILRGIDMIEFPKKIAKNAANLIKKLCRDNPSERLG 619 Query: 441 SRK-GAAEIKRHPFFQGLNWALIR--WTAPPETP 349 + K G +I++H +F+G NW +R PP P Sbjct: 620 NLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIP 653
>KGP1B_HUMAN (P14619) cGMP-dependent protein kinase 1, beta isozyme (EC| 2.7.11.12) (cGK 1 beta) (cGKI-beta) Length = 686 Score = 55.8 bits (133), Expect = 1e-07 Identities = 34/94 (36%), Positives = 52/94 (55%), Gaps = 4/94 (4%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPA-VSYQARDLIRGLLVKEPEHRLG 442 I +YELL G PF GP +T N++ +G+ + P ++ A +LI+ L P RLG Sbjct: 561 ILMYELLTGSPPFSGPDPMKTY-NIILRGIDMIEFPKKIAKNAANLIKKLCRDNPSERLG 619 Query: 441 SRK-GAAEIKRHPFFQGLNWALIR--WTAPPETP 349 + K G +I++H +F+G NW +R PP P Sbjct: 620 NLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIP 653
>KGP1B_BOVIN (P21136) cGMP-dependent protein kinase 1, beta isozyme (EC| 2.7.11.12) (cGK 1 beta) (cGKI-beta) Length = 686 Score = 55.8 bits (133), Expect = 1e-07 Identities = 34/94 (36%), Positives = 52/94 (55%), Gaps = 4/94 (4%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPA-VSYQARDLIRGLLVKEPEHRLG 442 I +YELL G PF GP +T N++ +G+ + P ++ A +LI+ L P RLG Sbjct: 561 ILMYELLTGSPPFSGPDPMKTY-NIILRGIDMIEFPKKIAKNAANLIKKLCRDNPSERLG 619 Query: 441 SRK-GAAEIKRHPFFQGLNWALIR--WTAPPETP 349 + K G +I++H +F+G NW +R PP P Sbjct: 620 NLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIP 653
>KS6A5_PONPY (Q5R4K3) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1)| Length = 802 Score = 55.8 bits (133), Expect = 1e-07 Identities = 33/81 (40%), Positives = 47/81 (58%), Gaps = 3/81 (3%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKF--PDSPAVSYQARDLIRGLLVKEPEHRL 445 + +YELL G +PF G + + + LK P +S A+DLI+ LL+K+P+ RL Sbjct: 243 VLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSALAKDLIQHLLMKDPKKRL 302 Query: 444 G-SRKGAAEIKRHPFFQGLNW 385 G + A EIK H FFQ +NW Sbjct: 303 GCGPRDADEIKEHLFFQKINW 323 Score = 34.3 bits (77), Expect = 0.30 Identities = 22/67 (32%), Positives = 31/67 (46%), Gaps = 9/67 (13%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPA---------VSYQARDLIRGLLV 466 + LY +L G+ PF+ T T+ V K VS +A+DLI+GLL Sbjct: 610 VILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNVSQEAKDLIQGLLT 669 Query: 465 KEPEHRL 445 +P RL Sbjct: 670 VDPNKRL 676
>KS6A5_HUMAN (O75582) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1) (Nuclear| mitogen-and stress-activated protein kinase 1) (90 kDa ribosomal protein S6 kinase 5) (RSK-like protein kinase) (RSKL) Length = 802 Score = 55.8 bits (133), Expect = 1e-07 Identities = 33/81 (40%), Positives = 47/81 (58%), Gaps = 3/81 (3%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKF--PDSPAVSYQARDLIRGLLVKEPEHRL 445 + +YELL G +PF G + + + LK P +S A+DLI+ LL+K+P+ RL Sbjct: 243 VLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSALAKDLIQRLLMKDPKKRL 302 Query: 444 G-SRKGAAEIKRHPFFQGLNW 385 G + A EIK H FFQ +NW Sbjct: 303 GCGPRDADEIKEHLFFQKINW 323 Score = 34.3 bits (77), Expect = 0.30 Identities = 22/67 (32%), Positives = 31/67 (46%), Gaps = 9/67 (13%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPA---------VSYQARDLIRGLLV 466 + LY +L G+ PF+ T T+ V K VS +A+DLI+GLL Sbjct: 610 VILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNVSQEAKDLIQGLLT 669 Query: 465 KEPEHRL 445 +P RL Sbjct: 670 VDPNKRL 676
>KGP1A_RABIT (O77676) cGMP-dependent protein kinase 1, alpha isozyme (EC| 2.7.11.12) (CGK 1 alpha) (cGKI-alpha) Length = 670 Score = 55.8 bits (133), Expect = 1e-07 Identities = 34/94 (36%), Positives = 52/94 (55%), Gaps = 4/94 (4%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPA-VSYQARDLIRGLLVKEPEHRLG 442 I +YELL G PF GP +T N++ +G+ + P ++ A +LI+ L P RLG Sbjct: 545 ILMYELLTGSPPFSGPDPMKTY-NIILRGIDMIEFPKKIAKNAANLIKKLCRDNPSERLG 603 Query: 441 SRK-GAAEIKRHPFFQGLNWALIR--WTAPPETP 349 + K G +I++H +F+G NW +R PP P Sbjct: 604 NLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIP 637
>KGP1A_HUMAN (Q13976) cGMP-dependent protein kinase 1, alpha isozyme (EC| 2.7.11.12) (CGK 1 alpha) (cGKI-alpha) Length = 670 Score = 55.8 bits (133), Expect = 1e-07 Identities = 34/94 (36%), Positives = 52/94 (55%), Gaps = 4/94 (4%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPA-VSYQARDLIRGLLVKEPEHRLG 442 I +YELL G PF GP +T N++ +G+ + P ++ A +LI+ L P RLG Sbjct: 545 ILMYELLTGSPPFSGPDPMKTY-NIILRGIDMIEFPKKIAKNAANLIKKLCRDNPSERLG 603 Query: 441 SRK-GAAEIKRHPFFQGLNWALIR--WTAPPETP 349 + K G +I++H +F+G NW +R PP P Sbjct: 604 NLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIP 637
>KGP1A_BOVIN (P00516) cGMP-dependent protein kinase 1, alpha isozyme (EC| 2.7.11.12) (CGK 1 alpha) (cGKI-alpha) Length = 670 Score = 55.8 bits (133), Expect = 1e-07 Identities = 34/94 (36%), Positives = 52/94 (55%), Gaps = 4/94 (4%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPA-VSYQARDLIRGLLVKEPEHRLG 442 I +YELL G PF GP +T N++ +G+ + P ++ A +LI+ L P RLG Sbjct: 545 ILMYELLTGSPPFSGPDPMKTY-NIILRGIDMIEFPKKIAKNAANLIKKLCRDNPSERLG 603 Query: 441 SRK-GAAEIKRHPFFQGLNWALIR--WTAPPETP 349 + K G +I++H +F+G NW +R PP P Sbjct: 604 NLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIP 637
>KS6A3_MOUSE (P18654) Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1)| (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (MAP kinase-activated protein kinase 1b) (MAPKAPK1B) Length = 740 Score = 55.8 bits (133), Expect = 1e-07 Identities = 33/93 (35%), Positives = 51/93 (54%), Gaps = 3/93 (3%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 + ++E+L G PF+G ET+T ++ L P +S +A+ L+R L + P +RLG+ Sbjct: 256 VLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQ--FLSPEAQSLLRMLFKRNPANRLGA 313 Query: 438 -RKGAAEIKRHPFFQGLNWALI--RWTAPPETP 349 G EIKRH FF ++W + R PP P Sbjct: 314 GPDGVEEIKRHSFFSTIDWNKLYRREIHPPFKP 346
>KS6A3_HUMAN (P51812) Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1)| (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protei Length = 740 Score = 55.8 bits (133), Expect = 1e-07 Identities = 33/93 (35%), Positives = 51/93 (54%), Gaps = 3/93 (3%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 + ++E+L G PF+G ET+T ++ L P +S +A+ L+R L + P +RLG+ Sbjct: 256 VLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQ--FLSPEAQSLLRMLFKRNPANRLGA 313 Query: 438 -RKGAAEIKRHPFFQGLNWALI--RWTAPPETP 349 G EIKRH FF ++W + R PP P Sbjct: 314 GPDGVEEIKRHSFFSTIDWNKLYRREIHPPFKP 346
>KS6A2_HUMAN (Q15349) Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1)| (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (MAP kinase-activated protein kinase 1c) (MAPKAPK1C) Length = 733 Score = 55.8 bits (133), Expect = 1e-07 Identities = 29/79 (36%), Positives = 46/79 (58%), Gaps = 1/79 (1%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 + ++E+L G PF+G ET+ ++ L P +S +A+ L+R L + P +RLG+ Sbjct: 247 VLMFEMLTGSLPFQGKDRKETMALILKAKLGMPQF--LSGEAQSLLRALFKRNPCNRLGA 304 Query: 438 R-KGAAEIKRHPFFQGLNW 385 G EIKRHPFF ++W Sbjct: 305 GIDGVEEIKRHPFFVTIDW 323
>KPCL_MOUSE (P23298) Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta)| (PKC-L) Length = 683 Score = 55.8 bits (133), Expect = 1e-07 Identities = 31/95 (32%), Positives = 50/95 (52%), Gaps = 4/95 (4%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 + LYE+L G PF D+ +++ + +P + AR +++ + K P RLGS Sbjct: 542 VLLYEMLCGHAPFEAENEDDLFEAILNDEVVYPTW--LHEDARGILKSFMTKNPTMRLGS 599 Query: 438 --RKGAAEIKRHPFFQGLNWALI--RWTAPPETPK 346 + G EI RHPFF+ ++WA + R PP P+ Sbjct: 600 LTQGGEHEILRHPFFKEIDWAQLNHRQLEPPFRPR 634
>KAPC_ENCCU (Q8SRK8) Probable cAMP-dependent protein kinase catalytic subunit| (EC 2.7.11.11) Length = 322 Score = 55.5 bits (132), Expect = 1e-07 Identities = 38/101 (37%), Positives = 50/101 (49%), Gaps = 2/101 (1%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 + +YE+L G PF D ++ + FP VS AR LI GLL K RLG+ Sbjct: 192 VMIYEMLCGDPPFYDSSADAIYHKILESNVVFPHY--VSPVARCLITGLLDKNRATRLGT 249 Query: 438 RKGAAEIKRHPFFQGLNWALI--RWTAPPETPKSIVEASTL 322 KG EI HPFF+G++W + R PP P S+L Sbjct: 250 -KGICEIMGHPFFKGIDWHEVESRRIEPPFIPNPNTVLSSL 289
>AKT2A_XENLA (Q7ZX15) RAC-beta serine/threonine-protein kinase-A (EC 2.7.11.1)| (RAC-PK-beta-A) (Protein kinase Akt-2-A) (Protein kinase B, beta-A) (PKB beta-A) Length = 486 Score = 55.5 bits (132), Expect = 1e-07 Identities = 31/101 (30%), Positives = 54/101 (53%), Gaps = 3/101 (2%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRL-G 442 + +YE++ G+ PF ++ ++ + ++FP + +S +A+ L+ GLL K+P+ RL G Sbjct: 343 VVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRT--LSPEAKSLLAGLLKKDPKQRLGG 400 Query: 441 SRKGAAEIKRHPFFQGLNWALI--RWTAPPETPKSIVEAST 325 A E+ H FF +NW + R PP P+ E T Sbjct: 401 GPNDAQEVMSHRFFVSINWQDVTERKLTPPFKPQVTSEIDT 441
>SGK1_RAT (Q06226) Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 1) Length = 430 Score = 55.5 bits (132), Expect = 1e-07 Identities = 32/90 (35%), Positives = 48/90 (53%), Gaps = 2/90 (2%) Frame = -2 Query: 612 LYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGSRK 433 LYE+LYG PF E N++++ L+ + ++ AR L+ GLL K+ RLG++ Sbjct: 287 LYEMLYGLPPFYSRNTAEMYDNILNKPLQLKN---ITNSARHLLEGLLQKDRTKRLGAKD 343 Query: 432 GAAEIKRHPFFQGLNW--ALIRWTAPPETP 349 EIK H FF +NW + + PP P Sbjct: 344 DFMEIKSHIFFSLINWDDLINKKITPPFNP 373
>AKT1_HUMAN (P31749) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase B) (PKB) (C-AKT) Length = 480 Score = 55.5 bits (132), Expect = 1e-07 Identities = 30/101 (29%), Positives = 57/101 (56%), Gaps = 3/101 (2%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRL-G 442 + +YE++ G+ PF +++ ++ + ++FP + + +A+ L+ GLL K+P+ RL G Sbjct: 337 VVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRT--LGPEAKSLLSGLLKKDPKQRLGG 394 Query: 441 SRKGAAEIKRHPFFQGLNWALI--RWTAPPETPKSIVEAST 325 + A EI +H FF G+ W + + +PP P+ E T Sbjct: 395 GSEDAKEIMQHRFFAGIVWQHVYEKKLSPPFKPQVTSETDT 435
>PK2_DICDI (P28178) Protein kinase 2 (EC 2.7.11.1)| Length = 479 Score = 55.1 bits (131), Expect = 2e-07 Identities = 28/76 (36%), Positives = 45/76 (59%) Frame = -2 Query: 612 LYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGSRK 433 LYE+L G PF +++ LK P +S +A+ L+ GLL +E + RLG+ K Sbjct: 340 LYEMLTGLPPFYSQNVSTMYQKILNGELKIPTY--ISPEAKSLLEGLLTREVDKRLGT-K 396 Query: 432 GAAEIKRHPFFQGLNW 385 G E+K+HP+F+ ++W Sbjct: 397 GGGEVKQHPWFKNIDW 412
>KPCT_MOUSE (Q02111) Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)| Length = 707 Score = 55.1 bits (131), Expect = 2e-07 Identities = 31/93 (33%), Positives = 52/93 (55%), Gaps = 2/93 (2%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 + +YE+L G++PF G +E ++ +P + +A+DL+ L V+EPE RLG Sbjct: 567 VLVYEMLIGQSPFHGQDEEELFHSIRMDNPFYPRW--LEREAKDLLVKLFVREPEKRLGV 624 Query: 438 RKGAAEIKRHPFFQGLNWALI--RWTAPPETPK 346 R +I++HP F+ +NW + + PP PK Sbjct: 625 R---GDIRQHPLFREINWEELERKEIDPPFRPK 654
>GRK5_RAT (Q62833) G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK5) Length = 590 Score = 55.1 bits (131), Expect = 2e-07 Identities = 30/79 (37%), Positives = 49/79 (62%), Gaps = 3/79 (3%) Frame = -2 Query: 612 LYELLYGKTPFRGPGNDETLTNVVSQGLKFPD--SPAVSYQARDLIRGLLVKEPEHRLGS 439 +YE++ G++PFRG V + L+ + SP S +A+ + LL K+ + RLG Sbjct: 375 IYEMIEGQSPFRGRKEKVKREEVDRRVLETEEVYSPKFSEEAKSICNMLLTKDSKQRLGC 434 Query: 438 RK-GAAEIKRHPFFQGLNW 385 ++ GAAE+KRHPFF+ +N+ Sbjct: 435 QEEGAAEVKRHPFFRNMNF 453
>KPCD_CANFA (Q5PU49) Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta)| Length = 674 Score = 55.1 bits (131), Expect = 2e-07 Identities = 31/93 (33%), Positives = 50/93 (53%), Gaps = 2/93 (2%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 + LYE+L G++PF G DE ++ +P ++ +++D++ LL ++ RLG Sbjct: 534 VLLYEMLIGQSPFHGDDEDELFESIRVDTPHYP--RWITKESKDILEKLLERDTTKRLGV 591 Query: 438 RKGAAEIKRHPFFQGLNWALI--RWTAPPETPK 346 IK HPFF+ +NW L+ R PP PK Sbjct: 592 ---TGNIKIHPFFKTINWTLLEKRAVEPPFKPK 621
>KPCD_RAT (P09215) Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta)| Length = 673 Score = 54.7 bits (130), Expect = 2e-07 Identities = 30/93 (32%), Positives = 50/93 (53%), Gaps = 2/93 (2%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 + LYE+L G++PF G DE ++ +P ++ +++D++ L ++P RLG Sbjct: 534 VLLYEMLIGQSPFHGDDEDELFESIRVDTPHYP--RWITKESKDIMEKLFERDPAKRLGV 591 Query: 438 RKGAAEIKRHPFFQGLNWALI--RWTAPPETPK 346 I+ HPFF+ +NW L+ R PP PK Sbjct: 592 ---TGNIRLHPFFKTINWNLLEKRKVEPPFKPK 621
>AKT2B_XENLA (Q6IP76) RAC-beta serine/threonine-protein kinase-B (EC 2.7.11.1)| (RAC-PK-beta-B) (Protein kinase Akt-2-B) (Protein kinase B, beta-B) (PKB beta-B) Length = 485 Score = 54.7 bits (130), Expect = 2e-07 Identities = 31/101 (30%), Positives = 54/101 (53%), Gaps = 3/101 (2%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRL-G 442 + +YE++ G+ PF ++ ++ + +FP + +S +A+ L+ GLL K+P+ RL G Sbjct: 342 VVMYEMMCGRLPFYNQDHERLFELILMEETRFPRT--LSPEAKSLLAGLLKKDPKQRLGG 399 Query: 441 SRKGAAEIKRHPFFQGLNWALI--RWTAPPETPKSIVEAST 325 A E+ H FF +NW + R +PP P+ E T Sbjct: 400 GPDDAQEVMSHGFFASINWQDVTERKLSPPFKPQVTSEIDT 440
>AKT2_HUMAN (P31751) RAC-beta serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta) Length = 481 Score = 54.7 bits (130), Expect = 2e-07 Identities = 30/101 (29%), Positives = 54/101 (53%), Gaps = 3/101 (2%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRL-G 442 + +YE++ G+ PF ++ ++ + ++FP + +S +A+ L+ GLL K+P+ RL G Sbjct: 338 VVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRT--LSPEAKSLLAGLLKKDPKQRLGG 395 Query: 441 SRKGAAEIKRHPFFQGLNW--ALIRWTAPPETPKSIVEAST 325 A E+ H FF +NW + + PP P+ E T Sbjct: 396 GPSDAKEVMEHRFFLSINWQDVVQKKLLPPFKPQVTSEVDT 436
>KSG1_SCHPO (Q12701) Serine/threonine-protein kinase ksg1 (EC 2.7.11.1)| Length = 592 Score = 54.3 bits (129), Expect = 3e-07 Identities = 34/101 (33%), Positives = 51/101 (50%) Frame = -2 Query: 612 LYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGSRK 433 L+++L GK PF T +++ + P P +S A DLI+ LLV +P+ RL Sbjct: 302 LFQMLAGKPPFVAGNEYLTFQSILHLSYEIP--PDISDVASDLIKKLLVLDPKDRLT--- 356 Query: 432 GAAEIKRHPFFQGLNWALIRWTAPPETPKSIVEASTLTVAV 310 EI +HPFF G+ + W PP K S L+++V Sbjct: 357 -VDEIHQHPFFNGIKFDNTLWELPPPRLKPFGHTSVLSLSV 396
>PCK2_SCHPO (P36583) Protein kinase C-like 2 (EC 2.7.11.13)| Length = 1016 Score = 54.3 bits (129), Expect = 3e-07 Identities = 32/96 (33%), Positives = 52/96 (54%), Gaps = 6/96 (6%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARD---LIRGLLVKEPEHR 448 + +Y++L G++PFRG +E ++S +P + RD +++ LL ++P+ R Sbjct: 871 VLIYQMLLGQSPFRGEDEEEIFDAILSDEPLYP-----IHMPRDSVSILQQLLTRDPKKR 925 Query: 447 LGSRKGAAE-IKRHPFFQGLNWALI--RWTAPPETP 349 LGS AE + HPFF +NW I + T PP P Sbjct: 926 LGSGPNDAEDVMTHPFFSNINWDDIYHKRTQPPYIP 961
>KPCE_HUMAN (Q02156) Protein kinase C epsilon type (EC 2.7.11.13)| (nPKC-epsilon) Length = 737 Score = 54.3 bits (129), Expect = 3e-07 Identities = 27/96 (28%), Positives = 52/96 (54%), Gaps = 5/96 (5%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLG- 442 + +YE++ G+ PF D+ +++ + +P +S +A +++ + K P RLG Sbjct: 595 VLMYEMMAGQPPFEADNEDDLFESILHDDVLYP--VWLSKEAVSILKAFMTKNPHKRLGC 652 Query: 441 --SRKGAAEIKRHPFFQGLNWALI--RWTAPPETPK 346 S+ G IK+HPFF+ ++W L+ + PP P+ Sbjct: 653 VASQNGEDAIKQHPFFKEIDWVLLEQKKIKPPFKPR 688
>AKT1_BOVIN (Q01314) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase B) (PKB) Length = 480 Score = 54.3 bits (129), Expect = 3e-07 Identities = 30/101 (29%), Positives = 57/101 (56%), Gaps = 3/101 (2%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRL-G 442 + +YE++ G+ PF +++ ++ + ++FP + +S +A+ L+ GLL K+P+ RL G Sbjct: 337 VVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRT--LSPEAKSLLSGLLKKDPKQRLGG 394 Query: 441 SRKGAAEIKRHPFFQGLNWALI--RWTAPPETPKSIVEAST 325 + A EI +H FF + W + + +PP P+ E T Sbjct: 395 GSEDAKEIMQHRFFASIVWQDVYEKKLSPPFKPQVTSETDT 435
>KPCG_RAT (P63319) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| Length = 697 Score = 53.9 bits (128), Expect = 4e-07 Identities = 32/94 (34%), Positives = 50/94 (53%), Gaps = 3/94 (3%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 + LYE+L G+ PF G +E ++ Q + +P S +S +A + +G L K P RLGS Sbjct: 543 VLLYEMLAGQPPFDGEDEEELFQAIMEQTVTYPKS--LSREAVAICKGFLTKHPGKRLGS 600 Query: 438 -RKGAAEIKRHPFFQGLNWALIR--WTAPPETPK 346 G I+ H FF+ ++W + APP P+ Sbjct: 601 GPDGEPTIRAHGFFRWIDWERLERLEIAPPFRPR 634
>KPCG_RABIT (P10829) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| (PKC-delta) Length = 697 Score = 53.9 bits (128), Expect = 4e-07 Identities = 32/94 (34%), Positives = 50/94 (53%), Gaps = 3/94 (3%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 + LYE+L G+ PF G +E ++ Q + +P S +S +A + +G L K P RLGS Sbjct: 543 VLLYEMLAGQPPFDGEDEEELFQAIMEQTVTYPKS--LSREAVAICKGFLTKHPGKRLGS 600 Query: 438 -RKGAAEIKRHPFFQGLNWALIR--WTAPPETPK 346 G I+ H FF+ ++W + APP P+ Sbjct: 601 GPDGEPTIRAHGFFRWIDWERLERLEIAPPFRPR 634
>KPCG_MOUSE (P63318) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| Length = 697 Score = 53.9 bits (128), Expect = 4e-07 Identities = 32/94 (34%), Positives = 50/94 (53%), Gaps = 3/94 (3%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 + LYE+L G+ PF G +E ++ Q + +P S +S +A + +G L K P RLGS Sbjct: 543 VLLYEMLAGQPPFDGEDEEELFQAIMEQTVTYPKS--LSREAVAICKGFLTKHPGKRLGS 600 Query: 438 -RKGAAEIKRHPFFQGLNWALIR--WTAPPETPK 346 G I+ H FF+ ++W + APP P+ Sbjct: 601 GPDGEPTIRAHGFFRWIDWERLERLEIAPPFRPR 634
>KPC4_DROME (P83099) Putative protein kinase C, delta type homolog (EC| 2.7.11.13) Length = 643 Score = 53.9 bits (128), Expect = 4e-07 Identities = 32/94 (34%), Positives = 54/94 (57%), Gaps = 3/94 (3%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 + LYE+L G++PF G DE ++ ++ FP +S +A +++GLL K+ R+GS Sbjct: 502 VLLYEMLIGQSPFSGCDEDELFWSICNEIPWFP--VYISAEATGILKGLLEKDYTKRIGS 559 Query: 438 R-KGAAEIKRHPFFQGLNWALI--RWTAPPETPK 346 + A +I H FF+ ++W L+ R PP P+ Sbjct: 560 QYSPAGDIADHIFFRPIDWGLLEKRQIEPPFKPQ 593
>KPCG_BOVIN (P05128) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| (Fragment) Length = 682 Score = 53.9 bits (128), Expect = 4e-07 Identities = 32/94 (34%), Positives = 50/94 (53%), Gaps = 3/94 (3%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 + LYE+L G+ PF G +E ++ Q + +P S +S +A + +G L K P RLGS Sbjct: 528 VLLYEMLAGQPPFDGEDEEELFQAIMEQTVTYPKS--LSREAVAICKGFLTKHPAKRLGS 585 Query: 438 -RKGAAEIKRHPFFQGLNWALIR--WTAPPETPK 346 G I+ H FF+ ++W + APP P+ Sbjct: 586 GPDGEPTIRAHGFFRWIDWDRLERLEIAPPFRPR 619
>KPC1_LYTPI (Q25378) Protein kinase C (EC 2.7.11.13)| Length = 658 Score = 53.9 bits (128), Expect = 4e-07 Identities = 31/93 (33%), Positives = 49/93 (52%), Gaps = 3/93 (3%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 + LYE+L G+ PF G DE +++ +P S +S ++ + +G L K P RLGS Sbjct: 512 VLLYEMLAGQPPFDGEDEDELFQSIMEHVPSYPKS--MSRESVTMCKGFLTKHPGKRLGS 569 Query: 438 -RKGAAEIKRHPFFQGLNWALI--RWTAPPETP 349 G +I+ H FF+ ++W + R PP P Sbjct: 570 GPTGEQDIREHQFFRRIDWEKLANREIQPPFVP 602
>AKT1_CAEEL (Q17941) Serine/threonine-protein kinase akt-1 (EC 2.7.11.1)| (Protein kinase B akt-1) (PKB akt-1) Length = 541 Score = 53.9 bits (128), Expect = 4e-07 Identities = 33/101 (32%), Positives = 54/101 (53%), Gaps = 3/101 (2%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRL-G 442 + +YE++ G+ PF +++ +++ L+FP +S +AR L+ GLLVK+P RL G Sbjct: 379 VVMYEMMCGRLPFYSKDHNKLFELIMAGDLRFPSK--LSQEARTLLTGLLVKDPTQRLGG 436 Query: 441 SRKGAAEIKRHPFFQGLNWALI--RWTAPPETPKSIVEAST 325 + A EI R FF+ ++W + PP P E T Sbjct: 437 GPEDALEICRADFFRTVDWEATYRKEIEPPYKPNVQSETDT 477
>KPCG_HUMAN (P05129) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| Length = 697 Score = 53.1 bits (126), Expect = 6e-07 Identities = 32/89 (35%), Positives = 48/89 (53%), Gaps = 2/89 (2%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 + LYE+L G+ PF G +E ++ Q + +P S +S +A + +G L K P RLGS Sbjct: 543 VLLYEMLAGQPPFDGEDEEELFQAIMEQTVTYPKS--LSREAVAICKGFLTKHPGKRLGS 600 Query: 438 -RKGAAEIKRHPFFQGLNW-ALIRWTAPP 358 G I+ H FF+ ++W L R PP Sbjct: 601 GPDGEPTIRAHGFFRWIDWERLERLEIPP 629
>KPCE_RABIT (P10830) Protein kinase C epsilon type (EC 2.7.11.13)| (nPKC-epsilon) Length = 736 Score = 53.1 bits (126), Expect = 6e-07 Identities = 26/96 (27%), Positives = 52/96 (54%), Gaps = 5/96 (5%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLG- 442 + +YE++ G+ PF D+ +++ + +P +S +A +++ + K P RLG Sbjct: 594 VLMYEMMAGQPPFEADNEDDLFESILHDDVLYP--VWLSKEAVSILKAFMTKNPHKRLGC 651 Query: 441 --SRKGAAEIKRHPFFQGLNWALI--RWTAPPETPK 346 ++ G IK+HPFF+ ++W L+ + PP P+ Sbjct: 652 VAAQNGEDAIKQHPFFKEIDWVLLEQKKIKPPFKPR 687
>KPCE_RAT (P09216) Protein kinase C epsilon type (EC 2.7.11.13)| (nPKC-epsilon) Length = 737 Score = 53.1 bits (126), Expect = 6e-07 Identities = 26/96 (27%), Positives = 52/96 (54%), Gaps = 5/96 (5%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLG- 442 + +YE++ G+ PF D+ +++ + +P +S +A +++ + K P RLG Sbjct: 595 VLMYEMMAGQPPFEADNEDDLFESILHDDVLYP--VWLSKEAVSILKAFMTKNPHKRLGC 652 Query: 441 --SRKGAAEIKRHPFFQGLNWALI--RWTAPPETPK 346 ++ G IK+HPFF+ ++W L+ + PP P+ Sbjct: 653 VAAQNGEDAIKQHPFFKEIDWVLLEQKKMKPPFKPR 688
>KPCE_MOUSE (P16054) Protein kinase C epsilon type (EC 2.7.11.13)| (nPKC-epsilon) Length = 737 Score = 53.1 bits (126), Expect = 6e-07 Identities = 26/96 (27%), Positives = 52/96 (54%), Gaps = 5/96 (5%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLG- 442 + +YE++ G+ PF D+ +++ + +P +S +A +++ + K P RLG Sbjct: 595 VLMYEMMAGQPPFEADNEDDLFESILHDDVLYP--VWLSKEAVSILKAFMTKNPHKRLGC 652 Query: 441 --SRKGAAEIKRHPFFQGLNWALI--RWTAPPETPK 346 ++ G IK+HPFF+ ++W L+ + PP P+ Sbjct: 653 VAAQNGEDAIKQHPFFKEIDWVLLEQKKIKPPFKPR 688
>AKT2_RAT (P47197) RAC-beta serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta) Length = 481 Score = 53.1 bits (126), Expect = 6e-07 Identities = 29/101 (28%), Positives = 53/101 (52%), Gaps = 3/101 (2%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRL-G 442 + +YE++ G+ PF ++ ++ + ++FP + + +A+ L+ GLL K+P+ RL G Sbjct: 338 VVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRT--LGPEAKSLLAGLLKKDPKQRLGG 395 Query: 441 SRKGAAEIKRHPFFQGLNW--ALIRWTAPPETPKSIVEAST 325 A E+ H FF +NW + + PP P+ E T Sbjct: 396 GPSDAKEVMEHRFFLSINWQDVVQKKLLPPFKPQVTSEVDT 436
>AKT2_MOUSE (Q60823) RAC-beta serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta) Length = 481 Score = 53.1 bits (126), Expect = 6e-07 Identities = 29/101 (28%), Positives = 53/101 (52%), Gaps = 3/101 (2%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRL-G 442 + +YE++ G+ PF ++ ++ + ++FP + + +A+ L+ GLL K+P+ RL G Sbjct: 338 VVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRT--LGPEAKSLLAGLLKKDPKQRLGG 395 Query: 441 SRKGAAEIKRHPFFQGLNW--ALIRWTAPPETPKSIVEAST 325 A E+ H FF +NW + + PP P+ E T Sbjct: 396 GPSDAKEVMEHRFFLSINWQDVVQKKLLPPFKPQVTSEVDT 436
>AKT1_XENLA (Q98TY9) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase Akt-1) (Protein kinase B, alpha) (PKB alpha) (xAkt) Length = 481 Score = 53.1 bits (126), Expect = 6e-07 Identities = 30/101 (29%), Positives = 55/101 (54%), Gaps = 3/101 (2%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRL-G 442 + +YE++ G+ PF +++ ++ + ++FP + + +A+ L+ GLL K+P+ RL G Sbjct: 338 VVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRT--LLPEAKSLLSGLLKKDPKQRLGG 395 Query: 441 SRKGAAEIKRHPFFQGLNWALI--RWTAPPETPKSIVEAST 325 A EI +H FF G+ W + + PP P+ E T Sbjct: 396 GPDDAKEIMQHKFFAGIVWQDVYEKKLVPPFKPQVTSETDT 436
>PDPK1_DROME (Q9W0V1) 3-phosphoinositide-dependent protein kinase 1 (EC| 2.7.11.1) (dPDK-1) (Serine/threonine-protein kinase 61C) (dSTPK61) Length = 836 Score = 53.1 bits (126), Expect = 6e-07 Identities = 28/88 (31%), Positives = 44/88 (50%), Gaps = 3/88 (3%) Frame = -2 Query: 612 LYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGSRK 433 +Y+++ G PFRG + ++ + FP A DL+R LL +P RLG++ Sbjct: 500 VYQMIAGLPPFRGSNDYVIFKEILDCAVDFPQG--FDKDAEDLVRKLLRVDPRDRLGAQD 557 Query: 432 GAA---EIKRHPFFQGLNWALIRWTAPP 358 I+ HPFF G++W +R PP Sbjct: 558 EFGYYESIRAHPFFAGIDWQTLRQQTPP 585
>KPC2_DROME (P13677) Protein kinase C, eye isozyme (EC 2.7.11.13) (PKC)| (dPKC53E(EY)) (Protein INAC) (Inactivation no after-potential C protein) (Photoreceptor-specific PKC) (Eye-PKC) Length = 700 Score = 53.1 bits (126), Expect = 6e-07 Identities = 27/79 (34%), Positives = 41/79 (51%), Gaps = 1/79 (1%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 + L+E + G+ PF G N+ + FP S +A D+I L K+P +RLG+ Sbjct: 558 VLLFEFMAGQAPFEGDDETTVFRNIKDKKAVFPKH--FSVEAMDIITSFLTKKPNNRLGA 615 Query: 438 -RKGAAEIKRHPFFQGLNW 385 R EI HPFF+ ++W Sbjct: 616 GRYARQEITTHPFFRNVDW 634
>SSP1_SCHPO (P50526) Serine/threonine-protein kinase ssp1 (EC 2.7.11.1)| Length = 652 Score = 52.8 bits (125), Expect = 8e-07 Identities = 42/127 (33%), Positives = 63/127 (49%), Gaps = 11/127 (8%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 + L+ LL+G+ PF E +V++ L P +P + + RDL++ LL K+PE R+ Sbjct: 341 VTLFCLLFGRCPFNASMEYELFDKIVNERLNIPSTPDIGEEGRDLLKRLLCKDPEQRI-- 398 Query: 438 RKGAAEIKRHPF-FQGL----NWALIRWTAPPETPKSIVEASTLTVAVA------RKKKE 292 E+K HP+ GL W ++ T P + S VE ST VA A ++K Sbjct: 399 --TLVEVKLHPWTLDGLKDPEKW--LQNTDP--STVSRVEVSTDEVASAISLVGRLRRKL 452 Query: 291 GKCLEFR 271 GK FR Sbjct: 453 GKLFRFR 459
>MAST1_HUMAN (Q9Y2H9) Microtubule-associated serine/threonine-protein kinase 1| (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase) Length = 1570 Score = 52.8 bits (125), Expect = 8e-07 Identities = 32/79 (40%), Positives = 45/79 (56%), Gaps = 1/79 (1%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPD-SPAVSYQARDLIRGLLVKEPEHRLG 442 I LYE L G PF G +E V+S + +P+ A+ +A+ LI LL P RLG Sbjct: 575 IILYEFLVGCVPFFGDTPEELFGQVISDDILWPEGDEALPTEAQLLISSLLQTNPLVRLG 634 Query: 441 SRKGAAEIKRHPFFQGLNW 385 + GA E+K+H FF+ L+W Sbjct: 635 A-GGAFEVKQHSFFRDLDW 652
>KPC1_CAEEL (P34722) Protein kinase C-like 1 (EC 2.7.11.13) (PKC)| (Tetradecanoyl phorbol acetate resistant protein 1) Length = 704 Score = 52.8 bits (125), Expect = 8e-07 Identities = 33/102 (32%), Positives = 55/102 (53%), Gaps = 5/102 (4%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 + +YE+L G++PF G G DE +++++ FP + +S +A + L + P RLG Sbjct: 563 VLMYEMLVGQSPFHGEGEDELFDSILNERPYFPKT--ISKEAAKCLSALFDRNPNTRLGM 620 Query: 438 RK-GAAEIKRHPFFQGLNWALI--RWTAPPETP--KSIVEAS 328 + I++H FF+G++W R PP P KS +AS Sbjct: 621 PECPDGPIRQHCFFRGVDWKRFENRQVPPPFKPNIKSNSDAS 662
>LATS2_HUMAN (Q9NRM7) Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Large| tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Kinase phosphorylated during mitosis protein) (Warts-like kinase) Length = 1088 Score = 52.4 bits (124), Expect = 1e-06 Identities = 35/93 (37%), Positives = 50/93 (53%), Gaps = 3/93 (3%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVS--QGLKFPDSPAVSYQARDLIRGLLVKEPEHRL 445 + L+E+L G+ PF P ET V++ L P +S +ARDLI L +HRL Sbjct: 901 VILFEMLVGQPPFLAPTPTETQLKVINWENTLHIPAQVKLSPEARDLITKLCC-SADHRL 959 Query: 444 GSRKGAAEIKRHPFFQGLNWAL-IRWTAPPETP 349 G R GA ++K HPFF ++++ IR P P Sbjct: 960 G-RNGADDLKAHPFFSAIDFSSDIRKQPAPYVP 991
>JIL1_DROME (Q9V3I5) Chromosomal serine/threonine-protein kinase JIL-1 (EC| 2.7.11.1) Length = 1207 Score = 52.4 bits (124), Expect = 1e-06 Identities = 30/87 (34%), Positives = 50/87 (57%), Gaps = 5/87 (5%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAV----SYQARDLIRGLLVKEPEH 451 + +ELL G +PF + + + +S+ ++ + P + S ARD + +L K P+ Sbjct: 455 VLTFELLTGASPF-ATSDGQVQQSEISRRIQ-KEQPMIPSSFSANARDFVLKMLEKNPKR 512 Query: 450 RLG-SRKGAAEIKRHPFFQGLNWALIR 373 RLG + + A+EIK HPFF G+NW +R Sbjct: 513 RLGGNHRDASEIKEHPFFNGINWQELR 539
>KS6A_CAEEL (Q21734) Putative ribosomal protein S6 kinase alpha (EC 2.7.11.1)| Length = 784 Score = 52.4 bits (124), Expect = 1e-06 Identities = 37/128 (28%), Positives = 66/128 (51%), Gaps = 6/128 (4%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 + ++E+L G PF+G ++T+T ++ L P ++ +A+ L+R L + ++RLG+ Sbjct: 292 VLMFEMLTGHLPFQGRDRNDTMTQILKAKLSMPH--FLTQEAQSLLRALFKRNSQNRLGA 349 Query: 438 -RKGAAEIKRHPFFQGLNWA--LIRWTAPPETPK-SIVEASTL--TVAVARKKKEGKCLE 277 G EIKRH FF +++ L + PP P S V++++ R K+ L Sbjct: 350 GPDGVEEIKRHAFFAKIDFVKLLNKEIDPPFKPALSTVDSTSYFDPEFTKRTPKDSPALP 409 Query: 276 FRMNGDDI 253 NG +I Sbjct: 410 ASANGHEI 417 Score = 29.6 bits (65), Expect = 7.4 Identities = 19/67 (28%), Positives = 35/67 (52%), Gaps = 5/67 (7%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGND--ETLTNVVSQG---LKFPDSPAVSYQARDLIRGLLVKEPE 454 + L+ +L G TPF ND + + V G + P +S +A+DL+R +L +P Sbjct: 639 VLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKISMTHPVWDTISDEAKDLVRKMLDVDPN 698 Query: 453 HRLGSRK 433 R+ +++ Sbjct: 699 RRVTAKQ 705
>GRK5_HUMAN (P34947) G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK5) Length = 590 Score = 52.4 bits (124), Expect = 1e-06 Identities = 29/79 (36%), Positives = 49/79 (62%), Gaps = 3/79 (3%) Frame = -2 Query: 612 LYELLYGKTPFRGPGNDETLTNVVSQGLKFPD--SPAVSYQARDLIRGLLVKEPEHRLGS 439 +YE++ G++PFRG V + L+ + S S +A+ + + LL K+ + RLG Sbjct: 375 IYEMIEGQSPFRGRKEKVKREEVDRRVLETEEVYSHKFSEEAKSICKMLLTKDAKQRLGC 434 Query: 438 RK-GAAEIKRHPFFQGLNW 385 ++ GAAE+KRHPFF+ +N+ Sbjct: 435 QEEGAAEVKRHPFFRNMNF 453
>GRK5_BOVIN (P43249) G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK5) Length = 590 Score = 52.4 bits (124), Expect = 1e-06 Identities = 29/79 (36%), Positives = 49/79 (62%), Gaps = 3/79 (3%) Frame = -2 Query: 612 LYELLYGKTPFRGPGNDETLTNVVSQGLKFPD--SPAVSYQARDLIRGLLVKEPEHRLGS 439 +YE++ G++PFRG V + L+ + S S +A+ + + LL K+ + RLG Sbjct: 375 IYEMIEGQSPFRGRKEKVKREEVDRRVLETEEVYSHKFSEEAKSICKMLLTKDAKQRLGC 434 Query: 438 RK-GAAEIKRHPFFQGLNW 385 ++ GAAE+KRHPFF+ +N+ Sbjct: 435 QEEGAAEVKRHPFFRNMNF 453
>MAST1_MOUSE (Q9R1L5) Microtubule-associated serine/threonine-protein kinase 1| (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase) Length = 1566 Score = 52.0 bits (123), Expect = 1e-06 Identities = 32/79 (40%), Positives = 44/79 (55%), Gaps = 1/79 (1%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPD-SPAVSYQARDLIRGLLVKEPEHRLG 442 I LYE L G PF G +E V+S + +P+ A+ A+ LI LL P RLG Sbjct: 576 IILYEFLVGCVPFFGDTPEELFGQVISDDILWPEGDEALPTDAQLLISSLLQTNPLVRLG 635 Query: 441 SRKGAAEIKRHPFFQGLNW 385 + GA E+K+H FF+ L+W Sbjct: 636 A-GGAFEVKQHSFFRDLDW 653
>KGP2_HUMAN (Q13237) cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2)| (cGKII) (Type II cGMP-dependent protein kinase) Length = 762 Score = 52.0 bits (123), Expect = 1e-06 Identities = 32/81 (39%), Positives = 48/81 (59%), Gaps = 3/81 (3%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLT-NVVSQGLKFPDSP-AVSYQARDLIRGLLVKEPEHRL 445 I +YELL G PF G D+ +T N++ +G++ D P ++ + DLIR L + P RL Sbjct: 638 ILVYELLTGNPPFSGV--DQMMTYNLILKGIEKMDFPRKITRRPEDLIRRLCRQNPTERL 695 Query: 444 GSRK-GAAEIKRHPFFQGLNW 385 G+ K G +IK+H + G NW Sbjct: 696 GNLKNGINDIKKHRWLNGFNW 716
>AKT_MLVAT (P31748) AKT kinase transforming protein (EC 2.7.11.1)| Length = 501 Score = 52.0 bits (123), Expect = 1e-06 Identities = 29/101 (28%), Positives = 55/101 (54%), Gaps = 3/101 (2%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRL-G 442 + +YE++ G+ PF +++ ++ + ++FP + + +A+ L+ GLL K+P RL G Sbjct: 358 VVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRT--LGPEAKSLLSGLLKKDPTQRLGG 415 Query: 441 SRKGAAEIKRHPFFQGLNWALI--RWTAPPETPKSIVEAST 325 + A EI +H FF + W + + +PP P+ E T Sbjct: 416 GSEDAKEIMQHRFFANIVWQDVYEKKLSPPFKPQVTSETDT 456
>RIM15_YEAST (P43565) Serine/threonine-protein kinase RIM15 (EC 2.7.11.1)| Length = 1770 Score = 52.0 bits (123), Expect = 1e-06 Identities = 29/82 (35%), Positives = 46/82 (56%), Gaps = 7/82 (8%) Frame = -2 Query: 609 YELLYGKTPFRGPGNDETLTNVVSQGLKFPD-------SPAVSYQARDLIRGLLVKEPEH 451 +ELL G PF D ++S +++P+ ++ +A+DLI LLV +P Sbjct: 1179 FELLLGYPPFHAETPDAVFKKILSGVIQWPEFKNEEEEREFLTPEAKDLIEKLLVVDPAK 1238 Query: 450 RLGSRKGAAEIKRHPFFQGLNW 385 RLG+ KG EIK HP+F+ ++W Sbjct: 1239 RLGA-KGIQEIKDHPYFKNVDW 1259
>MAST1_RAT (Q810W7) Microtubule-associated serine/threonine-protein kinase 1| (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase) Length = 1570 Score = 52.0 bits (123), Expect = 1e-06 Identities = 32/79 (40%), Positives = 44/79 (55%), Gaps = 1/79 (1%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPD-SPAVSYQARDLIRGLLVKEPEHRLG 442 I LYE L G PF G +E V+S + +P+ A+ A+ LI LL P RLG Sbjct: 577 IILYEFLVGCVPFFGDTPEELFGQVISDDILWPEGDEALPTDAQLLISSLLQTNPLVRLG 636 Query: 441 SRKGAAEIKRHPFFQGLNW 385 + GA E+K+H FF+ L+W Sbjct: 637 A-GGAFEVKQHSFFRDLDW 654
>KS6A5_MOUSE (Q8C050) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1) (Nuclear| mitogen-and stress-activated protein kinase 1) (90 kDa ribosomal protein S6 kinase 5) (RSK-like protein kinase) (RLSK) Length = 863 Score = 52.0 bits (123), Expect = 1e-06 Identities = 30/81 (37%), Positives = 46/81 (56%), Gaps = 3/81 (3%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKF--PDSPAVSYQARDLIRGLLVKEPEHRL 445 + +YELL G +PF G + + + LK P +S A+DL++ LL+K+P+ RL Sbjct: 242 VLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSTVAKDLLQRLLMKDPKKRL 301 Query: 444 G-SRKGAAEIKRHPFFQGLNW 385 G + A EIK H FF+ + W Sbjct: 302 GCGPRDAEEIKEHLFFEKIKW 322 Score = 34.3 bits (77), Expect = 0.30 Identities = 22/67 (32%), Positives = 31/67 (46%), Gaps = 9/67 (13%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPA---------VSYQARDLIRGLLV 466 + LY +L G+ PF+ T T+ V K VS +A+DLI+GLL Sbjct: 674 VILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNVSQEAKDLIQGLLT 733 Query: 465 KEPEHRL 445 +P RL Sbjct: 734 VDPNKRL 740
>KPCL_RAT (Q64617) Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta)| (PKC-L) Length = 683 Score = 52.0 bits (123), Expect = 1e-06 Identities = 29/95 (30%), Positives = 48/95 (50%), Gaps = 4/95 (4%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 + LYE+L G PF D+ +++ + +P + A +++ + K P RLGS Sbjct: 542 VLLYEMLCGHAPFEAENEDDLFEAILNDEVVYP--TWLHEDATGILKSFMTKNPTMRLGS 599 Query: 438 --RKGAAEIKRHPFFQGLNWALI--RWTAPPETPK 346 + G EI RHPFF+ ++W + R PP P+ Sbjct: 600 LTQGGEHEILRHPFFKEIDWVQLNHRQLEPPFRPR 634
>GRK5_MOUSE (Q8VEB1) G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK5) Length = 590 Score = 52.0 bits (123), Expect = 1e-06 Identities = 29/79 (36%), Positives = 48/79 (60%), Gaps = 3/79 (3%) Frame = -2 Query: 612 LYELLYGKTPFRGPGNDETLTNVVSQGLKFPD--SPAVSYQARDLIRGLLVKEPEHRLGS 439 +YE++ G++PFRG V + L+ + S S +A+ + LL K+ + RLG Sbjct: 375 IYEMIEGQSPFRGRKEKVKREEVDRRVLETEEVYSSKFSEEAKSICNMLLTKDSKQRLGC 434 Query: 438 RK-GAAEIKRHPFFQGLNW 385 ++ GAAE+KRHPFF+ +N+ Sbjct: 435 QEEGAAEVKRHPFFRNMNF 453
>AKT1_RAT (P47196) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase B) (PKB) Length = 480 Score = 52.0 bits (123), Expect = 1e-06 Identities = 29/101 (28%), Positives = 55/101 (54%), Gaps = 3/101 (2%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRL-G 442 + +YE++ G+ PF +++ ++ + ++FP + + +A+ L+ GLL K+P RL G Sbjct: 337 VVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRT--LGPEAKSLLSGLLKKDPTQRLGG 394 Query: 441 SRKGAAEIKRHPFFQGLNWALI--RWTAPPETPKSIVEAST 325 + A EI +H FF + W + + +PP P+ E T Sbjct: 395 GSEDAKEIMQHRFFANIVWQDVYEKKLSPPFKPQVTSETDT 435
>KGP2_RAT (Q64595) cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2)| (cGKII) (Type II cGMP-dependent protein kinase) Length = 762 Score = 51.6 bits (122), Expect = 2e-06 Identities = 32/81 (39%), Positives = 48/81 (59%), Gaps = 3/81 (3%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLT-NVVSQGLKFPDSPA-VSYQARDLIRGLLVKEPEHRL 445 I +YELL G PF G D+ +T N++ +G++ D P ++ + DLIR L + P RL Sbjct: 638 ILVYELLTGNPPFSGI--DQMMTYNLILKGIEKMDFPRKITRRPEDLIRRLCRQNPTERL 695 Query: 444 GSRK-GAAEIKRHPFFQGLNW 385 G+ K G +IK+H + G NW Sbjct: 696 GNLKNGINDIKKHRWLNGFNW 716
>KGP2_MOUSE (Q61410) cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2)| (cGKII) (Type II cGMP-dependent protein kinase) Length = 762 Score = 51.6 bits (122), Expect = 2e-06 Identities = 32/81 (39%), Positives = 48/81 (59%), Gaps = 3/81 (3%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLT-NVVSQGLKFPDSPA-VSYQARDLIRGLLVKEPEHRL 445 I +YELL G PF G D+ +T N++ +G++ D P ++ + DLIR L + P RL Sbjct: 638 ILVYELLTGNPPFSGI--DQMMTYNLILKGIEKMDFPRKITRRPEDLIRRLCRQNPTERL 695 Query: 444 GSRK-GAAEIKRHPFFQGLNW 385 G+ K G +IK+H + G NW Sbjct: 696 GNLKNGINDIKKHRWLNGFNW 716
>STK38_HUMAN (Q15208) Serine/threonine-protein kinase 38 (EC 2.7.11.1) (NDR1| protein kinase) (Nuclear Dbf2-related kinase 1) Length = 465 Score = 51.6 bits (122), Expect = 2e-06 Identities = 32/84 (38%), Positives = 47/84 (55%), Gaps = 2/84 (2%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVS--QGLKFPDSPAVSYQARDLIRGLLVKEPEHRL 445 + +YE+L G PF ET V++ + L FP +S +A+DLI E EHR+ Sbjct: 310 VIMYEMLIGYPPFCSETPQETYKKVMNWKETLTFPPEVPISEKAKDLILRFCC-EWEHRI 368 Query: 444 GSRKGAAEIKRHPFFQGLNWALIR 373 G+ G EIK + FF+G++W IR Sbjct: 369 GA-PGVEEIKSNSFFEGVDWEHIR 391
>PRKX_MOUSE (Q922R0) Serine/threonine-protein kinase PRKX (EC 2.7.11.1)| (PKA-related protein kinase) Length = 355 Score = 51.2 bits (121), Expect = 2e-06 Identities = 32/94 (34%), Positives = 51/94 (54%), Gaps = 3/94 (3%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 I ++E+L G PF +++ + FP + + ++DLI+ LLV + RLG+ Sbjct: 229 ILIFEMLSGFPPFFDDNPFGIYQKILACKIDFPRQ--LDFTSKDLIKKLLVVDRTRRLGN 286 Query: 438 RK-GAAEIKRHPFFQGLNWALI--RWTAPPETPK 346 K GA +IKRH +F+G+ W + R PP PK Sbjct: 287 MKNGAEDIKRHRWFRGVEWESVPQRKLKPPIVPK 320
>KRAC_DICDI (P54644) RAC-family serine/threonine-protein kinase homolog (EC| 2.7.11.1) Length = 444 Score = 51.2 bits (121), Expect = 2e-06 Identities = 32/86 (37%), Positives = 44/86 (51%), Gaps = 1/86 (1%) Frame = -2 Query: 612 LYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGSRK 433 LYE+L G PF E ++ + L FP +S AR L+ LL ++PE RL Sbjct: 309 LYEMLTGLPPFYNQDVQEMYRKIMMEKLSFPHF--ISPDARSLLEQLLERDPEKRLADPN 366 Query: 432 GAAEIKRHPFFQGLNW-ALIRWTAPP 358 IKRHPFF+ ++W L + PP Sbjct: 367 ---LIKRHPFFRSIDWEQLFQKNIPP 389
>KPCL_HUMAN (P24723) Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta)| (PKC-L) Length = 682 Score = 51.2 bits (121), Expect = 2e-06 Identities = 29/95 (30%), Positives = 48/95 (50%), Gaps = 4/95 (4%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 + LYE+L G PF D+ +++ + +P + A +++ + K P RLGS Sbjct: 541 VLLYEMLCGHAPFEAENEDDLFEAILNDEVVYP--TWLHEDATGILKSFMTKNPTMRLGS 598 Query: 438 --RKGAAEIKRHPFFQGLNWALI--RWTAPPETPK 346 + G I RHPFF+ ++WA + R PP P+ Sbjct: 599 LTQGGEHAILRHPFFKEIDWAQLNHRQIEPPFRPR 633
>COT1_NEUCR (P38679) Serine/threonine-protein kinase cot-1 (EC 2.7.11.1)| (Colonial temperature-sensitive 1) Length = 598 Score = 50.8 bits (120), Expect = 3e-06 Identities = 33/91 (36%), Positives = 48/91 (52%), Gaps = 2/91 (2%) Frame = -2 Query: 612 LYELLYGKTPFRGPGNDETLTNVVS--QGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 ++E L G PF + +T +V+ L FPD + A +LIR L+ E+RLG Sbjct: 448 MFECLVGWPPFCAEDSHDTYRKIVNWRHSLYFPDDITLGVDAENLIRSLICNT-ENRLG- 505 Query: 438 RKGAAEIKRHPFFQGLNWALIRWTAPPETPK 346 R GA EIK H FF+G+ + +R P P+ Sbjct: 506 RGGAHEIKSHAFFRGVEFDSLRRIRAPFEPR 536
>KAPA_YEAST (P06244) cAMP-dependent protein kinase type 1 (EC 2.7.11.11) (PKA| 1) (CDC25-suppressing protein kinase) (PK-25) Length = 397 Score = 50.8 bits (120), Expect = 3e-06 Identities = 25/79 (31%), Positives = 45/79 (56%), Gaps = 1/79 (1%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 I +YE+L G TPF +T +++ L+FP P + +DL+ L+ ++ RLG+ Sbjct: 270 ILIYEMLAGYTPFYDSNTMKTYEKILNAELRFP--PFFNEDVKDLLSRLITRDLSQRLGN 327 Query: 438 -RKGAAEIKRHPFFQGLNW 385 + G ++K HP+F+ + W Sbjct: 328 LQNGTEDVKNHPWFKEVVW 346
>AKT1_MOUSE (P31750) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (AKT1 kinase) (Protein kinase B) (PKB) (C-AKT) (Thymoma viral proto-oncogene) Length = 480 Score = 50.8 bits (120), Expect = 3e-06 Identities = 29/101 (28%), Positives = 54/101 (53%), Gaps = 3/101 (2%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRL-G 442 + +YE++ G+ PF +++ ++ + + FP + + +A+ L+ GLL K+P RL G Sbjct: 337 VVMYEMMCGRLPFYNQDHEKLFELILMEEIAFPRT--LGPEAKSLLSGLLKKDPTQRLGG 394 Query: 441 SRKGAAEIKRHPFFQGLNWALI--RWTAPPETPKSIVEAST 325 + A EI +H FF + W + + +PP P+ E T Sbjct: 395 GSEDAKEIMQHRFFANIVWQDVYEKKLSPPFKPQVTSETDT 435
>KAPC_ASCSU (P49673) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) (PKA C) Length = 337 Score = 50.4 bits (119), Expect = 4e-06 Identities = 27/79 (34%), Positives = 45/79 (56%), Gaps = 1/79 (1%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 + +YE++ G PFRG DE ++ L+F S A+DL++ LL + RLG+ Sbjct: 212 VLIYEMMIGIPPFRGKTLDEIYEKIILGKLRFTRS--FDLFAKDLVKKLLQVDRTQRLGN 269 Query: 438 RK-GAAEIKRHPFFQGLNW 385 +K GAA++ H +F ++W Sbjct: 270 QKDGAADVMNHKWFTDIDW 288
>ROCK2_RAT (Q62868) Rho-associated protein kinase 2 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 2) (p164 ROCK-2) (RhoA-binding kinase 2) (p150 ROK-alpha) (ROKalpha) Length = 1379 Score = 50.4 bits (119), Expect = 4e-06 Identities = 36/95 (37%), Positives = 49/95 (51%), Gaps = 4/95 (4%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVV--SQGLKFPDSPAVSYQARDLIRGLLVKEPEHRL 445 +FL+E+L G TPF T + ++ L FP+ +S A++LI L + E RL Sbjct: 273 VFLFEMLVGDTPFYADSLVGTYSKIMDHKNSLCFPEDTEISKHAKNLICAFLT-DREVRL 331 Query: 444 GSRKGAAEIKRHPFFQG--LNWALIRWTAPPETPK 346 G R G EIK FF+ NW IR TA P P+ Sbjct: 332 G-RNGVEEIKSASFFKNDQWNWDNIRETAAPVVPE 365
>KPC1_CANAL (P43057) Protein kinase C-like 1 (EC 2.7.11.13) (PKC 1)| Length = 1097 Score = 50.4 bits (119), Expect = 4e-06 Identities = 26/79 (32%), Positives = 47/79 (59%), Gaps = 1/79 (1%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 + L+++L ++PF+G D+ + + +K+P + +S Q +++ LL K+P RLGS Sbjct: 958 VLLFQMLLCQSPFKGDDEDDIFNAIENDEVKYPIN--LSRQTVLVLQALLTKDPSQRLGS 1015 Query: 438 -RKGAAEIKRHPFFQGLNW 385 K A EI HP+F +N+ Sbjct: 1016 GPKDAEEIMEHPYFHDVNF 1034
>AKT2_CAEEL (Q9XTG7) Serine/threonine-protein kinase akt-2 (EC 2.7.11.1)| (Protein kinase B akt-2) (PKB akt-2) Length = 528 Score = 50.1 bits (118), Expect = 5e-06 Identities = 32/101 (31%), Positives = 52/101 (51%), Gaps = 3/101 (2%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 + +YE++ G+ PF N + + + LKFP+ +S +A L+ GLL + P RLG+ Sbjct: 366 VVMYEMMCGRLPFSAKENGKLFELITTCDLKFPN--RLSPEAVTLLSGLLERVPAKRLGA 423 Query: 438 -RKGAAEIKRHPFFQGLNW--ALIRWTAPPETPKSIVEAST 325 A E+ R FF+ ++W L + PP P + E T Sbjct: 424 GPDDAREVSRAEFFKDVDWEATLRKEVEPPFKPNVMSETDT 464
>GRK7_SPETR (Q9Z2G7) G protein-coupled receptor kinase 7 precursor (EC| 2.7.11.16) (G protein-coupled receptor kinase GRK7) Length = 548 Score = 49.7 bits (117), Expect = 7e-06 Identities = 30/95 (31%), Positives = 52/95 (54%), Gaps = 7/95 (7%) Frame = -2 Query: 612 LYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQ-----ARDLIRGLLVKEPEHR 448 +YE++ G+TPF+ + ++ + +K D A ++ +D+ R L K+PE R Sbjct: 376 IYEMVAGRTPFKDFKEKVSKEDLKERTMK--DEVAFHHENFTEETKDICRLFLAKKPEQR 433 Query: 447 LGSRKGAAEIKRHPFFQGLNWALIR--WTAPPETP 349 LGSR+ A + ++HPFFQ +N+ + PP P Sbjct: 434 LGSREKADDPRKHPFFQTVNFPRLEAGLVEPPFVP 468
>ARBK1_RAT (P26817) Beta-adrenergic receptor kinase 1 (EC 2.7.11.15)| (Beta-ARK-1) (G-protein-coupled receptor kinase 2) Length = 689 Score = 49.7 bits (117), Expect = 7e-06 Identities = 34/102 (33%), Positives = 54/102 (52%), Gaps = 7/102 (6%) Frame = -2 Query: 612 LYELLYGKTPFRG---PGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLG 442 L++LL G +PFR E ++ ++ PDS S + R L+ GLL ++ RLG Sbjct: 381 LFKLLRGHSPFRQHKTKDKHEIDRMTLTMAVELPDS--FSPELRSLLEGLLQRDVNRRLG 438 Query: 441 SR-KGAAEIKRHPFFQGLNWALI---RWTAPPETPKSIVEAS 328 +GA EIK PFF+ L+W ++ ++ P P+ V A+ Sbjct: 439 CLGRGAQEIKESPFFRSLDWQMVFLQKYPPPLIPPRGEVNAA 480
>KPC1_COCHE (O42632) Protein kinase C-like (EC 2.7.11.13)| Length = 1174 Score = 49.3 bits (116), Expect = 9e-06 Identities = 32/97 (32%), Positives = 51/97 (52%), Gaps = 6/97 (6%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARD---LIRGLLVKEPEHR 448 + +Y++L ++PFRG DE +++ +P + RD +++ LL +EPE R Sbjct: 1037 VLIYQMLLQQSPFRGEDEDEIYDAILADEPLYP-----IHMPRDSVSILQKLLTREPEMR 1091 Query: 447 LGSRK-GAAEIKRHPFFQGLNWALI--RWTAPPETPK 346 LGS A EI H FF+ +NW I + PP P+ Sbjct: 1092 LGSGPTDAQEIMSHAFFRNINWDDIYHKRVQPPFIPQ 1128
>ARBK1_MOUSE (Q99MK8) Beta-adrenergic receptor kinase 1 (EC 2.7.11.15)| (Beta-ARK-1) (G-protein-coupled receptor kinase 2) Length = 689 Score = 49.3 bits (116), Expect = 9e-06 Identities = 33/102 (32%), Positives = 54/102 (52%), Gaps = 7/102 (6%) Frame = -2 Query: 612 LYELLYGKTPFRG---PGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLG 442 L++LL G +PFR E ++ ++ PDS S + R L+ GLL ++ RLG Sbjct: 381 LFKLLRGHSPFRQHKTKDKHEIDRMTLTMAVELPDS--FSPELRSLLEGLLQRDVNRRLG 438 Query: 441 SR-KGAAEIKRHPFFQGLNWALI---RWTAPPETPKSIVEAS 328 +GA E+K PFF+ L+W ++ ++ P P+ V A+ Sbjct: 439 CLGRGAQEVKESPFFRSLDWQMVFLQKYPPPLIPPRGEVNAA 480
>ARBK1_MESAU (Q64682) Beta-adrenergic receptor kinase 1 (EC 2.7.11.15)| (Beta-ARK-1) (G-protein-coupled receptor kinase 2) Length = 689 Score = 49.3 bits (116), Expect = 9e-06 Identities = 33/102 (32%), Positives = 54/102 (52%), Gaps = 7/102 (6%) Frame = -2 Query: 612 LYELLYGKTPFRG---PGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLG 442 L++LL G +PFR E ++ ++ PDS S + R L+ GLL ++ RLG Sbjct: 381 LFKLLRGHSPFRQHKTKDKHEIDRMTLTMAVELPDS--FSPELRSLLEGLLQRDVNRRLG 438 Query: 441 SR-KGAAEIKRHPFFQGLNWALI---RWTAPPETPKSIVEAS 328 +GA E+K PFF+ L+W ++ ++ P P+ V A+ Sbjct: 439 CLGRGAQEVKESPFFRSLDWQMVFLQKYPPPLIPPRGEVNAA 480
>ARBK1_BOVIN (P21146) Beta-adrenergic receptor kinase 1 (EC 2.7.11.15)| (Beta-ARK-1) (G-protein-coupled receptor kinase 2) Length = 689 Score = 49.3 bits (116), Expect = 9e-06 Identities = 33/102 (32%), Positives = 54/102 (52%), Gaps = 7/102 (6%) Frame = -2 Query: 612 LYELLYGKTPFRG---PGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLG 442 L++LL G +PFR E ++ ++ PDS S + R L+ GLL ++ RLG Sbjct: 381 LFKLLRGHSPFRQHKTKDKHEIDRMTLTMAVELPDS--FSPELRSLLEGLLQRDVNRRLG 438 Query: 441 SR-KGAAEIKRHPFFQGLNWALI---RWTAPPETPKSIVEAS 328 +GA E+K PFF+ L+W ++ ++ P P+ V A+ Sbjct: 439 CLGRGAQEVKESPFFRSLDWQMVFLQKYPPPLIPPRGEVNAA 480
>RK_RAT (Q63651) Rhodopsin kinase precursor (EC 2.7.11.14) (RK) (G| protein-coupled receptor kinase 1) Length = 564 Score = 49.3 bits (116), Expect = 9e-06 Identities = 30/99 (30%), Positives = 51/99 (51%), Gaps = 7/99 (7%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPG----NDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEH 451 + LYE++ + PFR G N E ++S+ +K+P+ S ++D LL K+PE Sbjct: 380 VTLYEMIAARGPFRARGEKVENKELKQRIISEPVKYPEK--FSQASKDFCEQLLEKDPEK 437 Query: 450 RLGSRKGAAE-IKRHPFFQGLNWALIR--WTAPPETPKS 343 RLG R G + ++ + F+ ++W + PP P S Sbjct: 438 RLGFRDGTCDALRANVLFKDISWRQLEAGMLIPPFIPDS 476
>RK_MOUSE (Q9WVL4) Rhodopsin kinase precursor (EC 2.7.11.14) (RK) (G| protein-coupled receptor kinase 1) Length = 564 Score = 49.3 bits (116), Expect = 9e-06 Identities = 30/99 (30%), Positives = 51/99 (51%), Gaps = 7/99 (7%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPG----NDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEH 451 + LYE++ + PFR G N E ++S+ +K+P+ S ++D LL K+PE Sbjct: 380 VTLYEMIAARGPFRARGEKVENKELKQRIISEPVKYPEK--FSQASKDFCEQLLEKDPEK 437 Query: 450 RLGSRKGAAE-IKRHPFFQGLNWALIR--WTAPPETPKS 343 RLG R G + ++ + F+ ++W + PP P S Sbjct: 438 RLGFRDGTCDALRANVLFKDISWRQLEAGMLIPPFIPDS 476
>MYLK2_RABIT (P07313) Myosin light chain kinase 2, skeletal/cardiac muscle (EC| 2.7.11.18) (MLCK2) Length = 607 Score = 48.9 bits (115), Expect = 1e-05 Identities = 30/78 (38%), Positives = 42/78 (53%), Gaps = 2/78 (2%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDS--PAVSYQARDLIRGLLVKEPEHRL 445 + Y LL G +PF G + ETL NV+S F + AVS +A+D + L+VKE Sbjct: 481 VITYMLLSGLSPFLGDDDTETLNNVLSGNWYFDEETFEAVSDEAKDFVSNLIVKEQ---- 536 Query: 444 GSRKGAAEIKRHPFFQGL 391 G+R AA+ HP+ L Sbjct: 537 GARMSAAQCLAHPWLNNL 554
>KPC1_NEUCR (P87253) Protein kinase C-like (EC 2.7.11.13)| Length = 1142 Score = 48.9 bits (115), Expect = 1e-05 Identities = 31/97 (31%), Positives = 51/97 (52%), Gaps = 6/97 (6%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARD---LIRGLLVKEPEHR 448 + +Y++L ++PFRG DE +++ +P + RD +++ LL +EP+ R Sbjct: 1005 VLIYQMLLQQSPFRGEDEDEIYDAILADEPLYP-----IHMPRDSVSILQKLLTREPDQR 1059 Query: 447 LGSRK-GAAEIKRHPFFQGLNWALI--RWTAPPETPK 346 LGS A EI PFF+ +NW I + PP P+ Sbjct: 1060 LGSGPTDAQEIMSQPFFRNINWDDIYHKRVQPPFLPQ 1096
>STK38_MOUSE (Q91VJ4) Serine/threonine-protein kinase 38 (EC 2.7.11.1) (NDR1| protein kinase) (Nuclear Dbf2-related kinase 1) Length = 465 Score = 48.9 bits (115), Expect = 1e-05 Identities = 32/84 (38%), Positives = 46/84 (54%), Gaps = 2/84 (2%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVS--QGLKFPDSPAVSYQARDLIRGLLVKEPEHRL 445 + +YE+L G PF ET V++ + L FP VS +A+ LI E EHR+ Sbjct: 310 VIMYEMLIGYPPFCSETPQETYKKVMNWKETLTFPPEVPVSEKAKGLILRFCC-EWEHRI 368 Query: 444 GSRKGAAEIKRHPFFQGLNWALIR 373 G+ G EIK + FF+G++W IR Sbjct: 369 GA-PGVEEIKNNLFFEGVDWEHIR 391
>KPC1_TRIRE (Q99014) Protein kinase C-like (EC 2.7.11.13)| Length = 1139 Score = 48.5 bits (114), Expect = 2e-05 Identities = 30/97 (30%), Positives = 51/97 (52%), Gaps = 6/97 (6%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARD---LIRGLLVKEPEHR 448 + +Y++L ++PFRG DE +++ +P + RD +++ LL +EP+ R Sbjct: 1002 VLIYQMLLQQSPFRGEDEDEIYDAILADEPLYP-----IHMPRDSVSILQKLLTREPDQR 1056 Query: 447 LGSRK-GAAEIKRHPFFQGLNWALI--RWTAPPETPK 346 LGS A E+ PFF+ +NW I + PP P+ Sbjct: 1057 LGSGPTDAQEVMSQPFFRNINWDDIYHKRVQPPFLPQ 1093
>GRK1_CAEBR (Q622Z7) G protein-coupled receptor kinase 1 (EC 2.7.11.16)| Length = 640 Score = 48.5 bits (114), Expect = 2e-05 Identities = 37/94 (39%), Positives = 45/94 (47%), Gaps = 10/94 (10%) Frame = -2 Query: 612 LYELLYGKTPFRGPGN----DETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRL 445 +YE++ GK PFR +E V K+ S S AR L RGLL KEP RL Sbjct: 391 IYEMIEGKAPFRQRKEKVKREEVERRVREDQEKY--SEKFSEAARTLCRGLLHKEPGFRL 448 Query: 444 GSRK------GAAEIKRHPFFQGLNWALIRWTAP 361 G R+ GA EI+ HPFF + A R P Sbjct: 449 GCRRVGKPEDGAEEIRAHPFFNTADTATGREPVP 482
>ARBK1_HUMAN (P25098) Beta-adrenergic receptor kinase 1 (EC 2.7.11.15)| (Beta-ARK-1) (G-protein coupled receptor kinase 2) Length = 689 Score = 48.5 bits (114), Expect = 2e-05 Identities = 33/102 (32%), Positives = 53/102 (51%), Gaps = 7/102 (6%) Frame = -2 Query: 612 LYELLYGKTPFRG---PGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLG 442 L++LL G +PFR E ++ ++ PDS S + L+ GLL ++ RLG Sbjct: 381 LFKLLRGHSPFRQHKTKDKHEIDRMTLTMAVELPDS--FSPELHSLLEGLLQRDVNRRLG 438 Query: 441 SR-KGAAEIKRHPFFQGLNWALI---RWTAPPETPKSIVEAS 328 +GA E+K PFF+ L+W ++ R+ P P+ V A+ Sbjct: 439 CLGRGAQEVKESPFFRSLDWQMVFLQRYPPPLIPPRGEVNAA 480
>KPC1_ASPNG (Q00078) Protein kinase C-like (EC 2.7.11.13)| Length = 1096 Score = 48.5 bits (114), Expect = 2e-05 Identities = 31/97 (31%), Positives = 51/97 (52%), Gaps = 6/97 (6%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARD---LIRGLLVKEPEHR 448 + +Y++L ++PFRG DE +++ +P + RD +++ LL +EPE R Sbjct: 959 VLIYQMLLQQSPFRGEDEDEIYDAILADEPLYP-----IHMPRDSVSILQKLLTREPELR 1013 Query: 447 LGSRK-GAAEIKRHPFFQGLNWALI--RWTAPPETPK 346 LGS A E+ H FF+ +NW I + PP P+ Sbjct: 1014 LGSGPTDAQEVMSHAFFRNINWDDIYHKRVPPPFLPQ 1050
>PDPK1_RAT (O55173) 3-phosphoinositide-dependent protein kinase 1 (EC| 2.7.11.1) (Protein kinase B kinase) (PkB kinase) Length = 559 Score = 48.5 bits (114), Expect = 2e-05 Identities = 27/88 (30%), Positives = 42/88 (47%), Gaps = 2/88 (2%) Frame = -2 Query: 612 LYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGSRK 433 +Y+L+ G PFR ++ FP+ +ARDL+ LLV + RLG + Sbjct: 275 IYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEK--FFPKARDLVEKLLVLDATKRLGCEE 332 Query: 432 --GAAEIKRHPFFQGLNWALIRWTAPPE 355 G +K HPFF+ + W + PP+ Sbjct: 333 MEGYGPLKAHPFFESITWENLHQQTPPK 360
>PDPK1_HUMAN (O15530) 3-phosphoinositide-dependent protein kinase 1 (EC| 2.7.11.1) (hPDK1) Length = 556 Score = 48.1 bits (113), Expect = 2e-05 Identities = 27/88 (30%), Positives = 42/88 (47%), Gaps = 2/88 (2%) Frame = -2 Query: 612 LYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGSRK 433 +Y+L+ G PFR ++ FP+ +ARDL+ LLV + RLG + Sbjct: 272 IYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEK--FFPKARDLVEKLLVLDATKRLGCEE 329 Query: 432 --GAAEIKRHPFFQGLNWALIRWTAPPE 355 G +K HPFF+ + W + PP+ Sbjct: 330 MEGYGPLKAHPFFESVTWENLHQQTPPK 357
>KPC1B_CAEEL (P34885) Protein kinase C-like 1B (EC 2.7.11.13) (PKC1B)| Length = 707 Score = 48.1 bits (113), Expect = 2e-05 Identities = 26/96 (27%), Positives = 50/96 (52%), Gaps = 5/96 (5%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLG- 442 + +YE++ G+ PF D+ +++ + +P +S +A ++++ + K RLG Sbjct: 565 VLMYEMMAGQPPFEADNEDDLFEAILNDDVLYP--VWLSKEAVNILKAFMTKNAGKRLGC 622 Query: 441 --SRKGAAEIKRHPFFQGLNWALI--RWTAPPETPK 346 S+ G I+ HPFF+ ++W + R PP PK Sbjct: 623 VVSQGGEDAIRAHPFFREIDWDALESRQVKPPFKPK 658
>GRK6_HUMAN (P43250) G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK6) Length = 576 Score = 47.8 bits (112), Expect = 3e-05 Identities = 31/79 (39%), Positives = 43/79 (54%), Gaps = 3/79 (3%) Frame = -2 Query: 612 LYELLYGKTPFRGPGNDETLTNVVSQGLKFPD--SPAVSYQARDLIRGLLVKEPEHRLGS 439 LYE++ G++PF+ V + P+ S S QAR L LL K+P RLG Sbjct: 375 LYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEYSERFSPQARSLCSQLLCKDPAERLGC 434 Query: 438 RKGAA-EIKRHPFFQGLNW 385 R G+A E+K HP F+ LN+ Sbjct: 435 RGGSAREVKEHPLFKKLNF 453
>PDPK1_MOUSE (Q9Z2A0) 3-phosphoinositide-dependent protein kinase 1 (EC| 2.7.11.1) (mPDK1) Length = 559 Score = 47.8 bits (112), Expect = 3e-05 Identities = 27/88 (30%), Positives = 42/88 (47%), Gaps = 2/88 (2%) Frame = -2 Query: 612 LYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGSRK 433 +Y+L+ G PFR ++ FP+ +ARDL+ LLV + RLG + Sbjct: 275 IYQLVAGLPPFRAGNEYLIFQKIIKLEYHFPEK--FFPKARDLVEKLLVLDATKRLGCEE 332 Query: 432 --GAAEIKRHPFFQGLNWALIRWTAPPE 355 G +K HPFF+ + W + PP+ Sbjct: 333 MEGYGPLKAHPFFETITWENLHQQTPPK 360
>PRKX_HUMAN (P51817) Serine/threonine-protein kinase PRKX (EC 2.7.11.1)| (Protein kinase PKX1) Length = 358 Score = 47.4 bits (111), Expect = 3e-05 Identities = 30/101 (29%), Positives = 51/101 (50%), Gaps = 3/101 (2%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 I ++E+L G PF +++ + FP + + +DLI+ LLV + RLG+ Sbjct: 232 ILIFEMLSGFPPFFDDNPFGIYQKILAGKIDFPRH--LDFHVKDLIKKLLVVDRTRRLGN 289 Query: 438 RK-GAAEIKRHPFFQGLNWALI--RWTAPPETPKSIVEAST 325 K GA ++K H +F+ ++W + R PP PK + T Sbjct: 290 MKNGANDVKHHRWFRSVDWEAVPQRKLKPPIVPKIAGDGDT 330
>LATS1_HUMAN (O95835) Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large| tumor suppressor homolog 1) (WARTS protein kinase) (h-warts) Length = 1130 Score = 47.4 bits (111), Expect = 3e-05 Identities = 31/81 (38%), Positives = 46/81 (56%), Gaps = 2/81 (2%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVS--QGLKFPDSPAVSYQARDLIRGLLVKEPEHRL 445 + L+E+L G+ PF ET V++ L P +S +A DLI L + PE RL Sbjct: 938 VILFEMLVGQPPFLAQTPLETQMKVINWQTSLHIPPQAKLSPEASDLIIKLC-RGPEDRL 996 Query: 444 GSRKGAAEIKRHPFFQGLNWA 382 G + GA EIK HPFF+ ++++ Sbjct: 997 G-KNGADEIKAHPFFKTIDFS 1016
>AURKB_MOUSE (O70126) Serine/threonine-protein kinase 12 (EC 2.7.11.1)| (Aurora-related kinase 2) (Serine/threonine-protein kinase 5) (STK-1) (Aurora-B) Length = 345 Score = 47.4 bits (111), Expect = 3e-05 Identities = 29/72 (40%), Positives = 36/72 (50%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 + YEL+ G PF P + ET +V LKFP S V A+DLI LL P RL Sbjct: 266 VLCYELMVGNPPFESPSHSETYRRIVKVDLKFPSS--VPSGAQDLISKLLKHNPWQRL-- 321 Query: 438 RKGAAEIKRHPF 403 AE+ HP+ Sbjct: 322 --PLAEVAAHPW 331
>GRK1_CAEEL (Q09537) G protein-coupled receptor kinase 1 (EC 2.7.11.16)| Length = 642 Score = 47.4 bits (111), Expect = 3e-05 Identities = 34/81 (41%), Positives = 41/81 (50%), Gaps = 10/81 (12%) Frame = -2 Query: 612 LYELLYGKTPFRGPGN----DETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRL 445 +YE++ GK PFR +E V K+ S S AR L RGLL KEP RL Sbjct: 392 IYEMIEGKAPFRQRKEKVKREEVERRVREDQEKY--SEKFSEAARTLCRGLLHKEPGFRL 449 Query: 444 GSRK------GAAEIKRHPFF 400 G R+ GA EI+ HPFF Sbjct: 450 GCRRVGRPEDGAEEIRAHPFF 470
>LATS2_MOUSE (Q7TSJ6) Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Large| tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Kinase phosphorylated during mitosis protein) Length = 1042 Score = 47.4 bits (111), Expect = 3e-05 Identities = 34/93 (36%), Positives = 49/93 (52%), Gaps = 3/93 (3%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVS--QGLKFPDSPAVSYQARDLIRGLLVKEPEHRL 445 + L+E+L G+ PF P ET V++ L P +S +ARDLI L + RL Sbjct: 859 VILFEMLVGQPPFLAPTPTETQLKVINWESTLHIPTQVRLSAEARDLITKLCC-AADCRL 917 Query: 444 GSRKGAAEIKRHPFFQGLNWAL-IRWTAPPETP 349 G R GA ++K HPFF ++++ IR P P Sbjct: 918 G-RDGADDLKAHPFFNTIDFSRDIRKQPAPYVP 949
>KPC1_YEAST (P24583) Protein kinase C-like 1 (EC 2.7.11.13) (PKC 1)| Length = 1151 Score = 47.0 bits (110), Expect = 4e-05 Identities = 24/79 (30%), Positives = 45/79 (56%), Gaps = 1/79 (1%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 + LY++L ++PF G DE +++ +P ++ + + +GLL K+PE RLG+ Sbjct: 1012 VLLYQMLLCQSPFSGDDEDEVFNAILTDEPLYPID--MAGEIVQIFQGLLTKDPEKRLGA 1069 Query: 438 -RKGAAEIKRHPFFQGLNW 385 + A E+ PFF+ +N+ Sbjct: 1070 GPRDADEVMEEPFFRNINF 1088
>ARBK2_RAT (P26819) Beta-adrenergic receptor kinase 2 (EC 2.7.11.15)| (Beta-ARK-2) (G-protein-coupled receptor kinase 3) Length = 688 Score = 47.0 bits (110), Expect = 4e-05 Identities = 33/94 (35%), Positives = 49/94 (52%), Gaps = 6/94 (6%) Frame = -2 Query: 612 LYELLYGKTPFRG---PGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLG 442 L++LL G +PFR E ++ ++ PD A S + R L+ GLL ++ RLG Sbjct: 381 LFKLLRGHSPFRQHKTKDKHEIDRMTLTVNVQLPD--AFSPELRSLLEGLLQRDVSQRLG 438 Query: 441 SRKGAA-EIKRHPFFQGLNW--ALIRWTAPPETP 349 G A E+K H FF+G++W +R PP P Sbjct: 439 CYGGGARELKEHIFFKGIDWQYVYLRKYPPPLIP 472
>KPCZ_RAT (P09217) Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)| Length = 592 Score = 46.6 bits (109), Expect = 6e-05 Identities = 29/102 (28%), Positives = 56/102 (54%), Gaps = 11/102 (10%) Frame = -2 Query: 618 IFLYELLYGKTPFR----GPG---NDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKE 460 + ++E++ G++PF P D ++ + ++ P +S +A +++G L K+ Sbjct: 439 VLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPRF--LSVKASHVLKGFLNKD 496 Query: 459 PEHRLGSRK--GAAEIKRHPFFQGLNWALI--RWTAPPETPK 346 P+ RLG R G ++IK H FF+ ++W L+ + T PP P+ Sbjct: 497 PKERLGCRPQTGFSDIKSHAFFRSIDWDLLEKKQTLPPFQPQ 538
>KPCZ_MOUSE (Q02956) Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)| Length = 592 Score = 46.6 bits (109), Expect = 6e-05 Identities = 29/102 (28%), Positives = 56/102 (54%), Gaps = 11/102 (10%) Frame = -2 Query: 618 IFLYELLYGKTPFR----GPG---NDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKE 460 + ++E++ G++PF P D ++ + ++ P +S +A +++G L K+ Sbjct: 439 VLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPRF--LSVKASHVLKGFLNKD 496 Query: 459 PEHRLGSRK--GAAEIKRHPFFQGLNWALI--RWTAPPETPK 346 P+ RLG R G ++IK H FF+ ++W L+ + T PP P+ Sbjct: 497 PKERLGCRPQTGFSDIKSHAFFRSIDWDLLEKKQTLPPFQPQ 538
>KPCI_BRARE (Q90XF2) Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota)| (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota) (Heart and soul protein) Length = 588 Score = 46.6 bits (109), Expect = 6e-05 Identities = 29/103 (28%), Positives = 55/103 (53%), Gaps = 13/103 (12%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGN---------DETLTNVVSQGLKFPDSPAVSYQARDLIRGLLV 466 + ++E++ G++PF G+ D ++ + ++ P S +S +A +++G L Sbjct: 433 VLMFEMMAGRSPFDIVGSSDNPDQNTEDYLFQVILEKQIRIPRS--LSVKAASVLKGFLN 490 Query: 465 KEPEHRLGS--RKGAAEIKRHPFFQGLNWALI--RWTAPPETP 349 KE + RLG + G A+I HPFF+ ++W L+ + PP P Sbjct: 491 KESKERLGCHPQTGFADIMAHPFFRNVDWDLMEQKQVVPPFKP 533
>GPRK1_DROME (P32865) G protein-coupled receptor kinase 1 (EC 2.7.11.16)| Length = 700 Score = 46.2 bits (108), Expect = 8e-05 Identities = 32/102 (31%), Positives = 54/102 (52%), Gaps = 7/102 (6%) Frame = -2 Query: 612 LYELLYGKTPFRGPGNDETLT---NVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLG 442 LY+LL G +PFR + L ++ ++ P+S S + ++L+ LL ++ RLG Sbjct: 382 LYKLLKGHSPFRQHKTKDKLEIDKMTLTMNVELPES--FSLELKNLLEMLLQRDVSKRLG 439 Query: 441 SR-KGAAEIKRHPFFQGLNWALI---RWTAPPETPKSIVEAS 328 GA E+K H FF G++W + ++T P P+ V A+ Sbjct: 440 CMGNGADEVKMHNFFCGIDWHQVYIQKYTPPLVPPRGEVNAA 481
>CBK1_EMENI (P0C1B1) Serine/threonine-protein kinase cbk1 (EC 2.7.11.1)| Length = 884 Score = 46.2 bits (108), Expect = 8e-05 Identities = 41/130 (31%), Positives = 50/130 (38%), Gaps = 40/130 (30%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVS--QGLKFP----DSPAVSYQARDLIRGLLVKEP 457 + LYE LYG TPF +T + Q L FP VS A D+I LL +E Sbjct: 641 VILYECLYGFTPFASEDRHQTKLKIHRHLQTLYFPVHRPTDKLVSADAIDVINSLL-QEK 699 Query: 456 EHRLGSRK----------------------------------GAAEIKRHPFFQGLNWAL 379 E RL S K A +IK H FF+G+NW Sbjct: 700 EFRLSSPKYKQNDAISSKPAKCSFYKPDSSNPSYQGHYVYPDDATDIKSHRFFRGINWEQ 759 Query: 378 IRWTAPPETP 349 I T+PP P Sbjct: 760 IHRTSPPFIP 769
>AURKB_HUMAN (Q96GD4) Serine/threonine-protein kinase 12 (EC 2.7.11.1) (Aurora-| and Ipl1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1-related kinase 2) (Aurora-related kinase 2) (STK-1) (Aurora-B) Length = 344 Score = 46.2 bits (108), Expect = 8e-05 Identities = 33/93 (35%), Positives = 44/93 (47%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 + YELL G PF ++ET +V LKFP S V A+DLI LL P RL Sbjct: 261 VLCYELLVGNPPFESASHNETYRRIVKVDLKFPAS--VPTGAQDLISKLLRHNPSERL-- 316 Query: 438 RKGAAEIKRHPFFQGLNWALIRWTAPPETPKSI 340 A++ HP+ + A R PP +S+ Sbjct: 317 --PLAQVSAHPWVR----ANSRRVLPPSALQSV 343
>GRK7_HUMAN (Q8WTQ7) G protein-coupled receptor kinase 7 precursor (EC| 2.7.11.16) (G protein-coupled receptor kinase GRK7) Length = 553 Score = 46.2 bits (108), Expect = 8e-05 Identities = 30/104 (28%), Positives = 54/104 (51%), Gaps = 7/104 (6%) Frame = -2 Query: 612 LYELLYGKTPFRG----PGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRL 445 +YE++ G+TPF+ ++ + +KF +A+D+ R L K+PE RL Sbjct: 381 IYEMVAGRTPFKDYKEKVSKEDLKQRTLQDEVKFQHDNFTE-EAKDICRLFLAKKPEQRL 439 Query: 444 GSRKGAAEIKRHPFFQGLNWALIR--WTAPPETP-KSIVEASTL 322 GSR+ + + ++H FF+ +N+ + PP P S+V A + Sbjct: 440 GSREKSDDPRKHHFFKTINFPRLEAGLIEPPFVPDPSVVYAKDI 483
>KPCI_PONPY (Q5R4K9) Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota)| Length = 587 Score = 45.8 bits (107), Expect = 1e-04 Identities = 27/103 (26%), Positives = 56/103 (54%), Gaps = 13/103 (12%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGN---------DETLTNVVSQGLKFPDSPAVSYQARDLIRGLLV 466 + ++E++ G++PF G+ D ++ + ++ P S +S +A +++ L Sbjct: 432 VLMFEMMAGRSPFDIVGSSDNPDQNTEDYLFQVILEKQIRIPRS--LSVKAASVLKSFLN 489 Query: 465 KEPEHRLGS--RKGAAEIKRHPFFQGLNWALI--RWTAPPETP 349 K+P+ RLG + G A+I+ HPFF+ ++W ++ + PP P Sbjct: 490 KDPKERLGCHPQTGFADIQGHPFFRNVDWDMMEQKQVVPPFKP 532
>KPCI_HUMAN (P41743) Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota)| (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota) (PRKC-lambda/iota) Length = 587 Score = 45.8 bits (107), Expect = 1e-04 Identities = 27/103 (26%), Positives = 56/103 (54%), Gaps = 13/103 (12%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGN---------DETLTNVVSQGLKFPDSPAVSYQARDLIRGLLV 466 + ++E++ G++PF G+ D ++ + ++ P S +S +A +++ L Sbjct: 432 VLMFEMMAGRSPFDIVGSSDNPDQNTEDYLFQVILEKQIRIPRS--LSVKAASVLKSFLN 489 Query: 465 KEPEHRLGS--RKGAAEIKRHPFFQGLNWALI--RWTAPPETP 349 K+P+ RLG + G A+I+ HPFF+ ++W ++ + PP P Sbjct: 490 KDPKERLGCHPQTGFADIQGHPFFRNVDWDMMEQKQVVPPFKP 532
>AURKB_RAT (O55099) Serine/threonine-protein kinase 12 (EC 2.7.11.1) (Aurora-| and Ipl1-like midbody-associated protein 1) (AIM-1) (Aurora-B) Length = 343 Score = 45.8 bits (107), Expect = 1e-04 Identities = 26/72 (36%), Positives = 35/72 (48%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 + YEL+ G PF P + ET +V LKFP S + A+DLI LL P RL Sbjct: 264 VLCYELMVGNPPFESPSHSETYRRIVKVDLKFPSSMPLG--AKDLISKLLKHNPSQRL-- 319 Query: 438 RKGAAEIKRHPF 403 ++ HP+ Sbjct: 320 --PLEQVSAHPW 329
>KPCI_MOUSE (Q62074) Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota)| (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota) Length = 586 Score = 45.8 bits (107), Expect = 1e-04 Identities = 27/103 (26%), Positives = 56/103 (54%), Gaps = 13/103 (12%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGN---------DETLTNVVSQGLKFPDSPAVSYQARDLIRGLLV 466 + ++E++ G++PF G+ D ++ + ++ P S +S +A +++ L Sbjct: 431 VLMFEMMAGRSPFDIVGSSDNPDQNTEDYLFQVILEKQIRIPRS--LSVKAASVLKSFLN 488 Query: 465 KEPEHRLGS--RKGAAEIKRHPFFQGLNWALI--RWTAPPETP 349 K+P+ RLG + G A+I+ HPFF+ ++W ++ + PP P Sbjct: 489 KDPKERLGCHPQTGFADIQGHPFFRNVDWDMMEQKQVVPPFKP 531
>KGP25_DROME (P32023) cGMP-dependent protein kinase, isozyme 2 forms cD5/T2 (EC| 2.7.11.12) (CGK) (Foraging protein) Length = 934 Score = 45.8 bits (107), Expect = 1e-04 Identities = 33/103 (32%), Positives = 54/103 (52%), Gaps = 6/103 (5%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPA-VSYQARDLIRGLLVKEPEHRLG 442 + ++ELL G PF G T N++ +G+ + P ++ A +LI+ L P RLG Sbjct: 809 VLMFELLTGTPPFTGSDPMRTY-NIILKGIDAIEFPRNITRNASNLIKKLCRDNPAERLG 867 Query: 441 -SRKGAAEIKRHPFFQGLNWALIR--WTAPPETP--KSIVEAS 328 R G +EI++H +F G W ++ PP P KS+V+ + Sbjct: 868 YQRGGISEIQKHKWFDGFYWWGLQNCTLEPPIKPAVKSVVDTT 910
>KGP24_DROME (Q03043) cGMP-dependent protein kinase, isozyme 2 forms| cD4/T1/T3A/T3B (EC 2.7.11.12) (CGK) (Foraging protein) Length = 1088 Score = 45.8 bits (107), Expect = 1e-04 Identities = 33/103 (32%), Positives = 54/103 (52%), Gaps = 6/103 (5%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPA-VSYQARDLIRGLLVKEPEHRLG 442 + ++ELL G PF G T N++ +G+ + P ++ A +LI+ L P RLG Sbjct: 963 VLMFELLTGTPPFTGSDPMRTY-NIILKGIDAIEFPRNITRNASNLIKKLCRDNPAERLG 1021 Query: 441 -SRKGAAEIKRHPFFQGLNWALIR--WTAPPETP--KSIVEAS 328 R G +EI++H +F G W ++ PP P KS+V+ + Sbjct: 1022 YQRGGISEIQKHKWFDGFYWWGLQNCTLEPPIKPAVKSVVDTT 1064
>ARBK2_BOVIN (P26818) Beta-adrenergic receptor kinase 2 (EC 2.7.11.15)| (Beta-ARK-2) (G-protein-coupled receptor kinase 3) Length = 688 Score = 45.8 bits (107), Expect = 1e-04 Identities = 32/102 (31%), Positives = 53/102 (51%), Gaps = 7/102 (6%) Frame = -2 Query: 612 LYELLYGKTPFRG---PGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLG 442 L++LL G +PFR E ++ ++ PD S + + L+ GLL ++ RLG Sbjct: 381 LFKLLRGHSPFRQHKTKDKHEIDRMTLTMNVELPD--VFSPELKSLLEGLLQRDVSKRLG 438 Query: 441 SRKGAA-EIKRHPFFQGLNWA---LIRWTAPPETPKSIVEAS 328 G+A E+K H FF+G++W L ++ P P+ V A+ Sbjct: 439 CHGGSAQELKTHDFFRGIDWQHVYLQKYPPPLIPPRGEVNAA 480
>MYLK2_HUMAN (Q9H1R3) Myosin light chain kinase 2, skeletal/cardiac muscle (EC| 2.7.11.18) (MLCK2) Length = 595 Score = 45.4 bits (106), Expect = 1e-04 Identities = 28/78 (35%), Positives = 41/78 (52%), Gaps = 2/78 (2%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDS--PAVSYQARDLIRGLLVKEPEHRL 445 + Y LL G +PF G + ETL NV+S F + AVS +A+D + L+VK+ Sbjct: 469 VITYMLLSGLSPFLGDDDTETLNNVLSGNWYFDEETFEAVSDEAKDFVSNLIVKDQR--- 525 Query: 444 GSRKGAAEIKRHPFFQGL 391 +R AA+ HP+ L Sbjct: 526 -ARMNAAQCLAHPWLNNL 542
>SNRK_RAT (Q63553) SNF-related serine/threonine-protein kinase (EC 2.7.11.1)| (SNF1-related kinase) Length = 746 Score = 45.4 bits (106), Expect = 1e-04 Identities = 26/77 (33%), Positives = 43/77 (55%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 + L+ L+ G+ PF+ + ETLT ++ K+ P VS RDLI +L ++P+ Sbjct: 203 VILFMLVCGQPPFQEANDSETLTMIMD--CKYTVPPRVSAGCRDLITRMLQRDPKR---- 256 Query: 438 RKGAAEIKRHPFFQGLN 388 R EI+ HP+ QG++ Sbjct: 257 RASLEEIESHPWLQGVD 273
>GIN4_YEAST (Q12263) Serine/threonine-protein kinase GIN4 (EC 2.7.11.1)| Length = 1142 Score = 45.4 bits (106), Expect = 1e-04 Identities = 28/76 (36%), Positives = 42/76 (55%), Gaps = 2/76 (2%) Frame = -2 Query: 618 IFLYELLYGKTPF-RGPGNDETLTNVVSQG-LKFPDSPAVSYQARDLIRGLLVKEPEHRL 445 + L+ LL G+ PF GN TL V +G + P +S +A+DLIR +L +PE R+ Sbjct: 219 VILFALLTGRLPFDEEDGNIRTLLLKVQKGEFEMPSDDEISREAQDLIRKILTVDPERRI 278 Query: 444 GSRKGAAEIKRHPFFQ 397 +R +I +HP Q Sbjct: 279 KTR----DILKHPLLQ 290
>SNRK_MOUSE (Q8VDU5) SNF-related serine/threonine-protein kinase (EC 2.7.11.1)| (SNF1-related kinase) Length = 748 Score = 45.4 bits (106), Expect = 1e-04 Identities = 26/77 (33%), Positives = 43/77 (55%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 + L+ L+ G+ PF+ + ETLT ++ K+ P VS RDLI +L ++P+ Sbjct: 203 VILFMLVCGQPPFQEANDSETLTMIMD--CKYTVPPRVSAGCRDLITRMLQRDPKR---- 256 Query: 438 RKGAAEIKRHPFFQGLN 388 R EI+ HP+ QG++ Sbjct: 257 RASLEEIESHPWLQGVD 273
>GRK7_PIG (Q8WP15) G protein-coupled receptor kinase 7 precursor (EC| 2.7.11.16) (G protein-coupled receptor kinase GRK7) Length = 553 Score = 45.4 bits (106), Expect = 1e-04 Identities = 23/80 (28%), Positives = 47/80 (58%), Gaps = 4/80 (5%) Frame = -2 Query: 612 LYELLYGKTPFRGP----GNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRL 445 +YE++ G+TPF+ ++ + + ++F + + +A+D+ R L K PE RL Sbjct: 381 IYEMVAGRTPFKDYKEKISKEDLKQRTLKEEVRFQHQ-SFTEEAKDICRLFLAKTPEQRL 439 Query: 444 GSRKGAAEIKRHPFFQGLNW 385 GSR+ + + ++H FF+ +N+ Sbjct: 440 GSREKSDDPRKHHFFKTINF 459
>LATS1_MOUSE (Q8BYR2) Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large| tumor suppressor homolog 1) (WARTS protein kinase) Length = 1129 Score = 45.1 bits (105), Expect = 2e-04 Identities = 31/81 (38%), Positives = 44/81 (54%), Gaps = 2/81 (2%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVV--SQGLKFPDSPAVSYQARDLIRGLLVKEPEHRL 445 + L E+L G+ PF ET V+ L P +S +A DLI L + PE RL Sbjct: 937 VILCEMLVGQPPFLAQTPLETQMKVIIWQTSLHIPPQAKLSPEASDLIIKLC-RGPEDRL 995 Query: 444 GSRKGAAEIKRHPFFQGLNWA 382 G + GA EIK HPFF+ ++++ Sbjct: 996 G-KNGADEIKAHPFFKTIDFS 1015
>KPCZ_HUMAN (Q05513) Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)| Length = 592 Score = 44.7 bits (104), Expect = 2e-04 Identities = 28/102 (27%), Positives = 55/102 (53%), Gaps = 11/102 (10%) Frame = -2 Query: 618 IFLYELLYGKTPFR----GPG---NDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKE 460 + ++E++ G++PF P D ++ + ++ P +S +A +++G L K+ Sbjct: 439 VLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPRF--LSVKASHVLKGFLNKD 496 Query: 459 PEHRLGSRK--GAAEIKRHPFFQGLNWALI--RWTAPPETPK 346 P+ RLG R G ++IK H FF+ ++W L+ + PP P+ Sbjct: 497 PKERLGCRPQTGFSDIKSHAFFRSIDWDLLEKKQALPPFQPQ 538
>KKCC1_MOUSE (Q8VBY2) Calcium/calmodulin-dependent protein kinase kinase 1 (EC| 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase alpha) (CaM-kinase kinase alpha) (CaM-KK alpha) (CaMKK alpha) (CaMKK 1) (CaM-kinase IV kinase) Length = 505 Score = 44.7 bits (104), Expect = 2e-04 Identities = 28/75 (37%), Positives = 42/75 (56%), Gaps = 3/75 (4%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLT---NVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHR 448 + LY +YGK PF +D LT + ++ + FP+ P VS +DLI +L K PE R Sbjct: 341 VTLYCFVYGKCPFI---DDYILTLHRKIKNEAVVFPEEPEVSEDLKDLILRMLDKNPETR 397 Query: 447 LGSRKGAAEIKRHPF 403 + G ++IK HP+ Sbjct: 398 I----GVSDIKLHPW 408
>GRK6_MOUSE (O70293) G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK6) Length = 576 Score = 44.7 bits (104), Expect = 2e-04 Identities = 32/83 (38%), Positives = 45/83 (54%), Gaps = 7/83 (8%) Frame = -2 Query: 612 LYELLYGKTPFRGPGND------ETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEH 451 LYE++ G++PF+ E L V++ ++ D S QAR L LL K+P Sbjct: 375 LYEMIAGQSPFQQRKKKIKREEVERLVKEVAE--EYTDR--FSSQARSLCSQLLSKDPAE 430 Query: 450 RLGSRKGAA-EIKRHPFFQGLNW 385 RLG R G A E+K HP F+ LN+ Sbjct: 431 RLGCRGGGAREVKEHPLFKKLNF 453
>KPC3_CAEEL (Q19266) Protein kinase C-like 3 (EC 2.7.11.13) (Atypical protein| kinase C-3) (aPKC3) Length = 597 Score = 44.7 bits (104), Expect = 2e-04 Identities = 30/105 (28%), Positives = 57/105 (54%), Gaps = 15/105 (14%) Frame = -2 Query: 618 IFLYELLYGKTPFR--GPGNDETLTN------VVSQGLKFPDSPAVSYQARDLIRGLLVK 463 + ++E++ G++PF G N E T ++ + ++ P S +S +A +++G L K Sbjct: 440 VLMFEMMAGRSPFDIVGMQNSEENTEDYLFQIILERQIRIPRS--LSVRASGILKGFLNK 497 Query: 462 EPEHRLGSR----KGAAEIKRHPFFQG-LNWALI--RWTAPPETP 349 +P RLG + +G ++K H FF+G ++W + + APP P Sbjct: 498 DPTERLGCKLDINEGLRDMKEHQFFRGFIDWEALEQKAVAPPYHP 542
>KS6A1_MOUSE (P18653) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 724 Score = 44.7 bits (104), Expect = 2e-04 Identities = 29/79 (36%), Positives = 42/79 (53%), Gaps = 3/79 (3%) Frame = -2 Query: 576 GPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGSRK-GAAEIKRHPFF 400 G ET+T ++ L P +S +A+ L+R L + P +RLGS GA EIKRH F+ Sbjct: 253 GKDRKETMTLILKAKLGMPQF--LSTEAQSLLRALFKRNPANRLGSGPDGAEEIKRHIFY 310 Query: 399 QGLNWALI--RWTAPPETP 349 ++W + R PP P Sbjct: 311 STIDWNKLYRREIKPPFKP 329
>KPCZ_RABIT (O19111) Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)| Length = 591 Score = 44.7 bits (104), Expect = 2e-04 Identities = 28/102 (27%), Positives = 55/102 (53%), Gaps = 11/102 (10%) Frame = -2 Query: 618 IFLYELLYGKTPFR----GPG---NDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKE 460 + ++E++ G++PF P D ++ + ++ P +S +A +++G L K+ Sbjct: 438 VLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPRF--LSVKASHVLKGFLNKD 495 Query: 459 PEHRLGSRK--GAAEIKRHPFFQGLNWALI--RWTAPPETPK 346 P+ RLG R G ++IK H FF+ ++W L+ + PP P+ Sbjct: 496 PKERLGCRPQTGFSDIKSHAFFRSIDWDLLEKKQALPPFQPQ 537
>DAPK2_MOUSE (Q8VDF3) Death-associated protein kinase 2 (EC 2.7.11.1) (DAP| kinase 2) (DAP-kinase-related protein 1) (DRP-1) Length = 370 Score = 44.3 bits (103), Expect = 3e-04 Identities = 32/101 (31%), Positives = 45/101 (44%), Gaps = 2/101 (1%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDS--PAVSYQARDLIRGLLVKEPEHRL 445 + Y LL G +PF G ETL N+ + F + S A+D IR LLVKE RL Sbjct: 215 VITYILLSGASPFLGDTKQETLANITAVSYDFDEEFFSQTSELAKDFIRKLLVKETRKRL 274 Query: 444 GSRKGAAEIKRHPFFQGLNWALIRWTAPPETPKSIVEASTL 322 + E RHP W P +T +++V ++ Sbjct: 275 TIQ----EALRHP-----------WITPVDTQQAMVRRESV 300
>YP150_YEAST (Q12152) Putative serine/threonine-protein kinase YPL150W (EC| 2.7.11.1) Length = 901 Score = 44.3 bits (103), Expect = 3e-04 Identities = 26/74 (35%), Positives = 38/74 (51%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 + LY L+ G PF +T +V++ K+ D+ + ARDLI LL K P G Sbjct: 220 VILYTLITGYLPFDDDDEAKTKWKIVNEEPKY-DAKVIPDDARDLISRLLAKNP----GE 274 Query: 438 RKGAAEIKRHPFFQ 397 R +++ RHPF Q Sbjct: 275 RPSLSQVLRHPFLQ 288
>ARBK2_HUMAN (P35626) Beta-adrenergic receptor kinase 2 (EC 2.7.11.15)| (Beta-ARK-2) (G-protein-coupled receptor kinase 3) Length = 688 Score = 44.3 bits (103), Expect = 3e-04 Identities = 31/102 (30%), Positives = 53/102 (51%), Gaps = 7/102 (6%) Frame = -2 Query: 612 LYELLYGKTPFRG---PGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLG 442 L++LL G +PFR E ++ ++ PD+ S + + L+ GLL ++ RLG Sbjct: 381 LFKLLRGHSPFRQHKTKDKHEIDRMTLTVNVELPDT--FSPELKSLLEGLLQRDVSKRLG 438 Query: 441 SRKGAA-EIKRHPFFQGLNWA---LIRWTAPPETPKSIVEAS 328 G + E+K H FF+G++W L ++ P P+ V A+ Sbjct: 439 CHGGGSQEVKEHSFFKGVDWQHVYLQKYPPPLIPPRGEVNAA 480
>GRK4_HUMAN (P32298) G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK4) (ITI1) Length = 578 Score = 44.3 bits (103), Expect = 3e-04 Identities = 28/80 (35%), Positives = 44/80 (55%), Gaps = 4/80 (5%) Frame = -2 Query: 612 LYELLYGKTPFRGPGNDETLTNVVSQGLKFPD---SPAVSYQARDLIRGLLVKEPEHRLG 442 +YE++ G +PF+ ++ V Q +K S S A+ + R LL K P RLG Sbjct: 376 IYEMIQGHSPFK-KYKEKVKWEEVDQRIKNDTEEYSEKFSEDAKSICRMLLTKNPSKRLG 434 Query: 441 SR-KGAAEIKRHPFFQGLNW 385 R +GAA +K+HP F+ +N+ Sbjct: 435 CRGEGAAGVKQHPVFKDINF 454
>KKCC1_RAT (P97756) Calcium/calmodulin-dependent protein kinase kinase 1 (EC| 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase alpha) (CaM-kinase kinase alpha) (CaM-KK alpha) (CaMKK alpha) (alpha CaMKK) (CaMKK 1) (CaM-kinase IV kinase) Length = 505 Score = 44.3 bits (103), Expect = 3e-04 Identities = 25/72 (34%), Positives = 39/72 (54%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 + LY +YGK PF + ++ + FP+ P VS + +DLI +L K PE R+ Sbjct: 341 VTLYCFVYGKCPFIDEYILALHRKIKNEAVVFPEEPEVSEELKDLILKMLDKNPETRI-- 398 Query: 438 RKGAAEIKRHPF 403 G ++IK HP+ Sbjct: 399 --GVSDIKLHPW 408
>KAPC_DICDI (P34099) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) Length = 648 Score = 44.3 bits (103), Expect = 3e-04 Identities = 25/79 (31%), Positives = 40/79 (50%), Gaps = 1/79 (1%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 I ++E+L G PF +++ + FP A+DLI+ LL + RLG+ Sbjct: 519 ILIFEMLAGYPPFYDDDTFAIYNKILAGRITFP--LGFDVDAKDLIKRLLTADRTRRLGA 576 Query: 438 RK-GAAEIKRHPFFQGLNW 385 K GA ++K H +F +NW Sbjct: 577 LKDGALDVKNHRWFSDINW 595
>KPC2_APLCA (Q16975) Calcium-independent protein kinase C (EC 2.7.11.13) (APL| II) Length = 743 Score = 43.9 bits (102), Expect = 4e-04 Identities = 27/97 (27%), Positives = 51/97 (52%), Gaps = 6/97 (6%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLG- 442 + +YE++ G+ PF D+ +++ + +P +S +A +++G + K P RLG Sbjct: 590 VLMYEMMAGQPPFEADNEDDLFESILHDDVLYP--VWLSKEAVSILKGFMTKNPAKRLGC 647 Query: 441 -SRKGAAE-IKRHPFF-QGLNWALI--RWTAPPETPK 346 + +G + I HPFF + ++W + R PP PK Sbjct: 648 VTTQGCEKAILVHPFFHEKIDWEALEQRKVKPPFKPK 684
>DAPK3_RAT (O88764) Death-associated protein kinase 3 (EC 2.7.11.1) (DAP| kinase 3) (DAP-like kinase) (Dlk) (ZIP-kinase) Length = 448 Score = 43.9 bits (102), Expect = 4e-04 Identities = 24/60 (40%), Positives = 34/60 (56%), Gaps = 2/60 (3%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDS--PAVSYQARDLIRGLLVKEPEHRL 445 + Y LL G +PF G ETLTN+ + F + + S A+D IR LLVK+P+ R+ Sbjct: 205 VITYILLSGASPFLGETKQETLTNISAVNYDFDEEYFSSTSELAKDFIRRLLVKDPKRRM 264
>DAPK3_MOUSE (O54784) Death-associated protein kinase 3 (EC 2.7.11.1) (DAP| kinase 3) (DAP-like kinase) (Dlk) (ZIP-kinase) Length = 448 Score = 43.9 bits (102), Expect = 4e-04 Identities = 24/60 (40%), Positives = 34/60 (56%), Gaps = 2/60 (3%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDS--PAVSYQARDLIRGLLVKEPEHRL 445 + Y LL G +PF G ETLTN+ + F + + S A+D IR LLVK+P+ R+ Sbjct: 205 VITYILLSGASPFLGETKQETLTNISAVNYDFDEEYFSSTSELAKDFIRRLLVKDPKRRM 264
>KDC2_DROME (P16912) Protein kinase DC2 (EC 2.7.11.1)| Length = 583 Score = 43.9 bits (102), Expect = 4e-04 Identities = 27/79 (34%), Positives = 44/79 (55%), Gaps = 1/79 (1%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 + +YE+L G PF ++S +++ + A+DLI+ LLV + RLG+ Sbjct: 457 VLIYEMLVGYPPFYDEQPFGIYEKILSGKIEWERH--MDPIAKDLIKKLLVNDRTKRLGN 514 Query: 438 RK-GAAEIKRHPFFQGLNW 385 K GA ++KRH +F+ LNW Sbjct: 515 MKNGADDVKRHRWFKHLNW 533
>STK6_XENLA (Q91820) Serine/threonine-protein kinase Eg2 (EC 2.7.11.1) (pEg2)| (p46Eg265) Length = 407 Score = 43.9 bits (102), Expect = 4e-04 Identities = 28/72 (38%), Positives = 36/72 (50%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 + YE L GK PF + ET + ++P P VS +ARDL+ LL P HRL Sbjct: 324 VLCYEFLVGKPPFETDTHQETYRRISKVEFQYP--PYVSEEARDLVSKLLKHNPNHRL-P 380 Query: 438 RKGAAEIKRHPF 403 KG E HP+ Sbjct: 381 LKGVLE---HPW 389
>IPL1_ASHGO (Q755C4) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 367 Score = 43.5 bits (101), Expect = 5e-04 Identities = 26/74 (35%), Positives = 37/74 (50%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 + YELL G PF + T ++ + L FPD V +AR LI LL +P G Sbjct: 294 VLTYELLVGSPPFEEESKELTYKRILKRNLIFPDH--VDTEARHLISRLLEYDP----GD 347 Query: 438 RKGAAEIKRHPFFQ 397 R E+K+HP+ + Sbjct: 348 RIPLKEVKKHPWIE 361
>KKCC2_MOUSE (Q8C078) Calcium/calmodulin-dependent protein kinase kinase 2 (EC| 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-kinase kinase beta) (CaM-KK beta) (CaMKK beta) Length = 588 Score = 43.5 bits (101), Expect = 5e-04 Identities = 26/72 (36%), Positives = 38/72 (52%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 + LY ++G+ PF + + SQ L+FPD P ++ +DLI +L K PE S Sbjct: 378 VTLYCFVFGQCPFMDERIMCLHSKIKSQALEFPDQPDIAEDLKDLITRMLDKNPE----S 433 Query: 438 RKGAAEIKRHPF 403 R EIK HP+ Sbjct: 434 RIVVPEIKLHPW 445
>KKCC2_HUMAN (Q96RR4) Calcium/calmodulin-dependent protein kinase kinase 2 (EC| 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-kinase kinase beta) (CaM-KK beta) (CaMKK beta) Length = 588 Score = 43.5 bits (101), Expect = 5e-04 Identities = 26/72 (36%), Positives = 38/72 (52%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 + LY ++G+ PF + + SQ L+FPD P ++ +DLI +L K PE S Sbjct: 378 VTLYCFVFGQCPFMDERIMCLHSKIKSQALEFPDQPDIAEDLKDLITRMLDKNPE----S 433 Query: 438 RKGAAEIKRHPF 403 R EIK HP+ Sbjct: 434 RIVVPEIKLHPW 445
>KKCC2_RAT (O88831) Calcium/calmodulin-dependent protein kinase kinase 2 (EC| 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-kinase kinase beta) (CaM-KK beta) (CaMKK beta) Length = 587 Score = 43.5 bits (101), Expect = 5e-04 Identities = 26/72 (36%), Positives = 38/72 (52%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDSPAVSYQARDLIRGLLVKEPEHRLGS 439 + LY ++G+ PF + + SQ L+FPD P ++ +DLI +L K PE S Sbjct: 377 VTLYCFVFGQCPFMDERIMCLHSKIKSQALEFPDQPDIAEDLKDLITRMLDKNPE----S 432 Query: 438 RKGAAEIKRHPF 403 R EIK HP+ Sbjct: 433 RIVVPEIKLHPW 444
>MYLK2_MOUSE (Q8VCR8) Myosin light chain kinase 2, skeletal/cardiac muscle (EC| 2.7.11.18) (MLCK2) (Fragment) Length = 240 Score = 43.5 bits (101), Expect = 5e-04 Identities = 27/78 (34%), Positives = 40/78 (51%), Gaps = 2/78 (2%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDS--PAVSYQARDLIRGLLVKEPEHRL 445 + Y LL G +PF G + ETL NV+S F + AVS +A+D + LL K+ R+ Sbjct: 114 VITYMLLSGLSPFLGDDDTETLNNVLSANWYFDEETFEAVSDEAKDFVSNLLTKDQSARM 173 Query: 444 GSRKGAAEIKRHPFFQGL 391 + + A HP+ L Sbjct: 174 SAEQCLA----HPWLNNL 187
>DAPK1_HUMAN (P53355) Death-associated protein kinase 1 (EC 2.7.11.1) (DAP| kinase 1) Length = 1432 Score = 43.1 bits (100), Expect = 6e-04 Identities = 25/60 (41%), Positives = 33/60 (55%), Gaps = 2/60 (3%) Frame = -2 Query: 618 IFLYELLYGKTPFRGPGNDETLTNVVSQGLKFPDS--PAVSYQARDLIRGLLVKEPEHRL 445 + Y LL G +PF G ETL NV + +F D S A+D IR LLVK+P+ R+ Sbjct: 205 VITYILLSGASPFLGDTKQETLANVSAVNYEFEDEYFSNTSALAKDFIRRLLVKDPKKRM 264 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 81,969,551 Number of Sequences: 219361 Number of extensions: 1593133 Number of successful extensions: 5515 Number of sequences better than 10.0: 439 Number of HSP's better than 10.0 without gapping: 5023 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5184 length of database: 80,573,946 effective HSP length: 107 effective length of database: 57,102,319 effective search space used: 5596027262 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
