>GPSN2_RAT (Q64232) Synaptic glycoprotein SC2|
          Length = 308

 Score = 75.1 bits (183), Expect = 1e-13
 Identities = 48/119 (40%), Positives = 62/119 (52%), Gaps = 6/119 (5%)
 Frame = -2

Query: 550 QMKIGFGIGVVCQIANFYCHILXRNLRSPTGSGGYQIPRG------FLFNIVTCANYTTE 389
           Q+K+   I V+CQ+ NF  H+  R+LR P GS   +IP        +LF +V+C NYT E
Sbjct: 193 QVKLALAIFVICQLGNFSIHMALRDLR-PAGSKTRKIPYPTKNPFTWLFLLVSCPNYTYE 251

Query: 388 IYQWLGFNIATQTVAGYVFLAVAAAIMTNWALGKHXRLRKLFDGKDGRPKYPRRWVILP 212
           +  W+GF I TQ V   +F  V    MT WA GKH    K F     R   P R  I+P
Sbjct: 252 VGSWIGFAIMTQCVPVALFSLVGFTQMTIWAKGKHRSYLKEF-----RDYPPLRMPIIP 305

>GPSN2_MOUSE (Q9CY27) Synaptic glycoprotein SC2|
          Length = 308

 Score = 74.7 bits (182), Expect = 2e-13
 Identities = 47/119 (39%), Positives = 62/119 (52%), Gaps = 6/119 (5%)
 Frame = -2

Query: 550 QMKIGFGIGVVCQIANFYCHILXRNLRSPTGSGGYQIPRG------FLFNIVTCANYTTE 389
           Q+K+   + V+CQ+ NF  H+  R+LR P GS   +IP        +LF +V+C NYT E
Sbjct: 193 QVKLALAVFVICQLGNFSIHMALRDLR-PAGSKTRKIPYPTKNPFTWLFLLVSCPNYTYE 251

Query: 388 IYQWLGFNIATQTVAGYVFLAVAAAIMTNWALGKHXRLRKLFDGKDGRPKYPRRWVILP 212
           +  W+GF I TQ V   +F  V    MT WA GKH    K F     R   P R  I+P
Sbjct: 252 VGSWIGFAILTQCVPVALFSLVGFTQMTIWAKGKHRSYLKEF-----RDYPPLRMPIIP 305

>GPSN2_HUMAN (Q9NZ01) Synaptic glycoprotein SC2|
          Length = 308

 Score = 73.9 bits (180), Expect = 3e-13
 Identities = 47/119 (39%), Positives = 62/119 (52%), Gaps = 6/119 (5%)
 Frame = -2

Query: 550 QMKIGFGIGVVCQIANFYCHILXRNLRSPTGSGGYQIPRG------FLFNIVTCANYTTE 389
           Q+K+   I V+CQ+ NF  H+  R+LR P GS   +IP        +LF +V+C NYT E
Sbjct: 193 QVKLALAIFVICQLGNFSIHMALRDLR-PAGSKTRKIPYPTKNPFTWLFLLVSCPNYTYE 251

Query: 388 IYQWLGFNIATQTVAGYVFLAVAAAIMTNWALGKHXRLRKLFDGKDGRPKYPRRWVILP 212
           +  W+GF I TQ +   +F  V    MT WA GKH    K F     R   P R  I+P
Sbjct: 252 VGSWIGFAIMTQCLPVALFSLVGFTQMTIWAKGKHRSYLKEF-----RDYPPLRMPIIP 305

>S5A1_MACFA (Q28891) 3-oxo-5-alpha-steroid 4-dehydrogenase 1 (EC 1.3.99.5)|
           (Steroid 5-alpha-reductase 1) (SR type 1)
          Length = 263

 Score = 69.7 bits (169), Expect = 5e-12
 Identities = 42/113 (37%), Positives = 59/113 (52%)
 Frame = -2

Query: 541 IGFGIGVVCQIANFYCHILXRNLRSPTGSGGYQIPRGFLFNIVTCANYTTEIYQWLGFNI 362
           IGFG+ +   + N +   + RNLR P G  GY+IPRG LF  VT ANY  EI +W G+ +
Sbjct: 157 IGFGLWLAGMLINIHSDHILRNLRKP-GDTGYKIPRGGLFEYVTAANYFGEIMEWCGYAL 215

Query: 361 ATQTVAGYVFLAVAAAIMTNWALGKHXRLRKLFDGKDGRPKYPRRWVILPPFL 203
           A+ +V G  F       ++  A   H    + F+      +YP+   IL PFL
Sbjct: 216 ASWSVQGAAFAFFTFCFLSGRAKEHHRWYLQKFE------EYPKFRKILIPFL 262

>S5A1_HUMAN (P18405) 3-oxo-5-alpha-steroid 4-dehydrogenase 1 (EC 1.3.99.5)|
           (Steroid 5-alpha-reductase 1) (SR type 1) (S5AR)
          Length = 259

 Score = 69.3 bits (168), Expect = 7e-12
 Identities = 41/113 (36%), Positives = 59/113 (52%)
 Frame = -2

Query: 541 IGFGIGVVCQIANFYCHILXRNLRSPTGSGGYQIPRGFLFNIVTCANYTTEIYQWLGFNI 362
           IGFG+ +   + N +   + RNLR P G  GY+IPRG LF  VT ANY  EI +W G+ +
Sbjct: 153 IGFGLWLTGMLINIHSDHILRNLRKP-GDTGYKIPRGGLFEYVTAANYFGEIMEWCGYAL 211

Query: 361 ATQTVAGYVFLAVAAAIMTNWALGKHXRLRKLFDGKDGRPKYPRRWVILPPFL 203
           A+ +V G  F       ++  A   H    + F+      +YP+   I+ PFL
Sbjct: 212 ASWSVQGAAFAFFTFCFLSGRAKEHHEWYLRKFE------EYPKFRKIIIPFL 258

>S5A1_RAT (P24008) 3-oxo-5-alpha-steroid 4-dehydrogenase 1 (EC 1.3.99.5)|
           (Steroid 5-alpha-reductase 1) (SR type 1)
          Length = 259

 Score = 67.0 bits (162), Expect = 3e-11
 Identities = 39/112 (34%), Positives = 58/112 (51%)
 Frame = -2

Query: 538 GFGIGVVCQIANFYCHILXRNLRSPTGSGGYQIPRGFLFNIVTCANYTTEIYQWLGFNIA 359
           GF + +V  + N +   + RNLR P G  GY+IPRG LF  V+ ANY  E+ +W GF +A
Sbjct: 154 GFALWLVGMVINIHSDHILRNLRKP-GETGYKIPRGGLFEYVSAANYFGELVEWCGFALA 212

Query: 358 TQTVAGYVFLAVAAAIMTNWALGKHXRLRKLFDGKDGRPKYPRRWVILPPFL 203
           + ++ G VF     + +   A   H    + F+       YP+   IL PF+
Sbjct: 213 SWSLQGVVFALFTLSTLLTRAKQHHQWYHEKFE------DYPKSRKILIPFV 258

>S5A2_RAT (P31214) 3-oxo-5-alpha-steroid 4-dehydrogenase 2 (EC 1.3.99.5)|
           (Steroid 5-alpha-reductase 2) (SR type 2) (5 alpha-SR2)
          Length = 254

 Score = 52.4 bits (124), Expect = 9e-07
 Identities = 35/101 (34%), Positives = 49/101 (48%)
 Frame = -2

Query: 505 NFYCHILXRNLRSPTGSGGYQIPRGFLFNIVTCANYTTEIYQWLGFNIATQTVAGYVFLA 326
           N +     R LR P G   Y+IPRG LF  V+ AN+  EI +W+G+ +AT +V  + F  
Sbjct: 160 NIHSDYTLRQLRKP-GEVIYRIPRGGLFTYVSGANFLGEIIEWIGYALATWSVPAFAFAF 218

Query: 325 VAAAIMTNWALGKHXRLRKLFDGKDGRPKYPRRWVILPPFL 203
                +   A   H    K+F  KD    YP+    L PF+
Sbjct: 219 FTLCFLGMQAFYHHRFYLKMF--KD----YPKSRKALIPFI 253

>S5A2_MOUSE (Q99N99) 3-oxo-5-alpha-steroid 4-dehydrogenase 2 (EC 1.3.99.5)|
           (Steroid 5-alpha-reductase 2) (SR type 2) (5 alpha-SR2)
          Length = 254

 Score = 52.4 bits (124), Expect = 9e-07
 Identities = 38/115 (33%), Positives = 55/115 (47%), Gaps = 4/115 (3%)
 Frame = -2

Query: 535 FGIGVVCQIA----NFYCHILXRNLRSPTGSGGYQIPRGFLFNIVTCANYTTEIYQWLGF 368
           F +GV   I     N +   + R LR P G   Y+IP+G LF  V+ AN+  EI +W+G+
Sbjct: 146 FSVGVFFFILGMGINIHSDCMLRQLRKP-GEVIYRIPQGGLFTYVSGANFLGEIIEWMGY 204

Query: 367 NIATQTVAGYVFLAVAAAIMTNWALGKHXRLRKLFDGKDGRPKYPRRWVILPPFL 203
            +AT +V  + F       +   A   H    K+F  KD    YP+    L PF+
Sbjct: 205 ALATWSVPAFAFAFFTLCFLGMQAFYHHRFYLKMF--KD----YPKSRKALIPFI 253

>S5A2_HUMAN (P31213) 3-oxo-5-alpha-steroid 4-dehydrogenase 2 (EC 1.3.99.5)|
           (Steroid 5-alpha-reductase 2) (SR type 2) (5 alpha-SR2)
           (Type II 5-alpha reductase)
          Length = 254

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 36/117 (30%), Positives = 55/117 (47%), Gaps = 4/117 (3%)
 Frame = -2

Query: 541 IGFGIGVVCQIA----NFYCHILXRNLRSPTGSGGYQIPRGFLFNIVTCANYTTEIYQWL 374
           I F +GV   I     N +   + R LR P G   Y+IP+G LF  V+ AN+  EI +W+
Sbjct: 144 IRFSLGVFLFILGMGINIHSDYILRQLRKP-GEISYRIPQGGLFTYVSGANFLGEIIEWI 202

Query: 373 GFNIATQTVAGYVFLAVAAAIMTNWALGKHXRLRKLFDGKDGRPKYPRRWVILPPFL 203
           G+ +AT ++    F   +   +   A   H    K+F+       YP+    L PF+
Sbjct: 203 GYALATWSLPALAFAFFSLCFLGLRAFHHHRFYLKMFE------DYPKSRKALIPFI 253

>S5A2_MACFA (Q28892) 3-oxo-5-alpha-steroid 4-dehydrogenase 2 (EC 1.3.99.5)|
           (Steroid 5-alpha-reductase 2) (SR type 2) (5 alpha-SR2)
          Length = 254

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 34/110 (30%), Positives = 53/110 (48%)
 Frame = -2

Query: 532 GIGVVCQIANFYCHILXRNLRSPTGSGGYQIPRGFLFNIVTCANYTTEIYQWLGFNIATQ 353
           G+GV     N +   + R LR P G   Y+IP+G LF  V+ AN+  EI +W+G+ +AT 
Sbjct: 156 GMGV-----NIHSDYILRQLRKP-GEITYRIPKGGLFTYVSGANFLGEIIEWIGYALATW 209

Query: 352 TVAGYVFLAVAAAIMTNWALGKHXRLRKLFDGKDGRPKYPRRWVILPPFL 203
           ++    F   +   +   A   H    K+F+       YP+    L PF+
Sbjct: 210 SLPALAFAFFSVCFLGLRAFHHHRFYLKMFE------DYPKSRKALIPFI 253

>S5A2_PIG (O18765) 3-oxo-5-alpha-steroid 4-dehydrogenase 2 (EC 1.3.99.5)|
           (Steroid 5-alpha-reductase 2) (SR type 2) (5 alpha-SR2)
          Length = 254

 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 36/117 (30%), Positives = 55/117 (47%), Gaps = 4/117 (3%)
 Frame = -2

Query: 541 IGFGIGVVCQIA----NFYCHILXRNLRSPTGSGGYQIPRGFLFNIVTCANYTTEIYQWL 374
           I F +GV   I     N +   + R LR P G   Y+IP+G LF  V+ AN+  EI +W+
Sbjct: 144 IRFSLGVFLFILGMGINIHSDYILRQLRKP-GEVIYKIPQGGLFTYVSGANFLGEIIEWI 202

Query: 373 GFNIATQTVAGYVFLAVAAAIMTNWALGKHXRLRKLFDGKDGRPKYPRRWVILPPFL 203
           G+ +AT ++    F   +   +   A   H    K+F+       YP+    L PF+
Sbjct: 203 GYALATWSLPALAFAFFSLCFLGLRAFHHHRFYVKMFE------DYPKSRKALIPFI 253

>DET2_ARATH (Q38944) Probable steroid reductase DET2 (EC 1.3.99.-)|
          Length = 262

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 36/114 (31%), Positives = 51/114 (44%), Gaps = 3/114 (2%)
 Frame = -2

Query: 535 FGIGVVCQIANFYCHILX-RNL--RSPTGSGGYQIPRGFLFNIVTCANYTTEIYQWLGFN 365
           F IG+V  I   Y +I   R L        GGY IPRG  F +V+C NY  E  +WLG+ 
Sbjct: 153 FVIGMVVFITGMYINITSDRTLVRLKKENRGGYVIPRGGWFELVSCPNYFGEAIEWLGWA 212

Query: 364 IATQTVAGYVFLAVAAAIMTNWALGKHXRLRKLFDGKDGRPKYPRRWVILPPFL 203
           + T + AG  F     + +   A   H      F     + +YP+    + PF+
Sbjct: 213 VMTWSWAGIGFFLYTCSNLFPRARASHKWYIAKF-----KEEYPKTRKAVIPFV 261

>PDZK3_RAT (Q9QZR8) PDZ domain-containing protein 3 (PDZ domain-containing|
            protein 2) (Plakophilin-related armadillo repeat
            protein-interacting PDZ protein)
          Length = 2766

 Score = 30.8 bits (68), Expect = 2.7
 Identities = 18/42 (42%), Positives = 24/42 (57%), Gaps = 6/42 (14%)
 Frame = -3

Query: 435  GASCSTS*HAQ------TTPPRSTNGSGSTSPPRPWRVTSSL 328
            GA  S+S HAQ      T+ PR T G+GS  PP+ W +  S+
Sbjct: 1384 GAGSSSSHHAQMVRSDQTSSPRKTGGTGS-PPPQQWALQPSV 1424

>MYPT1_RAT (Q10728) Protein phosphatase 1 regulatory subunit 12A (Myosin|
           phosphatase-targeting subunit 1) (Myosin phosphatase
           target subunit 1) (Protein phosphatase myosin-binding
           subunit) (MBSP) (Serine/threonine protein phosphatase
           PP1 smooth muscle reg
          Length = 1032

 Score = 30.0 bits (66), Expect = 4.6
 Identities = 15/45 (33%), Positives = 25/45 (55%)
 Frame = -3

Query: 465 RPAAAATRSHGASCSTS*HAQTTPPRSTNGSGSTSPPRPWRVTSS 331
           +P A+ T +H AS   +  A TTP  S+N    TSP + +  +++
Sbjct: 375 KPMASVTNAHTASTQAAPAAVTTPTLSSNQGTPTSPVKKFPTSTT 419

>DHSB_CYACA (P48933) Succinate dehydrogenase [ubiquinone] iron-sulfur protein|
           (EC 1.3.5.1) (IP)
          Length = 262

 Score = 29.6 bits (65), Expect = 6.0
 Identities = 17/72 (23%), Positives = 34/72 (47%)
 Frame = -3

Query: 246 GPSTLADG*SFLHSCEEDTVLARLVSRDSTFILFQCSKVESHHSISRKHSY*SCPVPAVK 67
           GP+ L     ++    +D  L+RL+S   ++ L++C  + +      KH      + ++K
Sbjct: 186 GPAVLLQAYRWIVDSRDDNTLSRLLSLKDSYKLYRCHTIMNCTKTCPKHLNPGKVIASIK 245

Query: 66  PQLCSPNVLMPK 31
            +L +  VL  K
Sbjct: 246 KRLLNLEVLGEK 257

>TRPI_PSEAE (P11720) HTH-type transcriptional regulator trpI (TrpBA operon|
           transcriptional activator)
          Length = 295

 Score = 29.3 bits (64), Expect = 7.9
 Identities = 33/115 (28%), Positives = 46/115 (40%), Gaps = 12/115 (10%)
 Frame = +2

Query: 224 PSARVLGPPILPVEQLPQA--XVLSKRPVGHDGRRHGKE--------DVTRHGLGGDVEP 373
           P+AR+L  P+L     PQA     + + +  +  R+G+         +    GLG  + P
Sbjct: 184 PAARLLQEPLLHTASRPQAWPAWAASQGLAAEALRYGQGFEHLYYLLEAAVAGLGVAIAP 243

Query: 374 EPLV--DLGGVVCACHDVEQEAPWDLVAAAAGRAPEVPXQDVAVEVCDLAHDPDA 532
           EPLV  DL     A       APW  +   A  A  VP +          HDP A
Sbjct: 244 EPLVRDDLAAGRLA-------APWGFIETDARLALWVPAR---------LHDPRA 282

>CAC1G_HUMAN (O43497) Voltage-dependent T-type calcium channel alpha-1G subunit|
            (Voltage-gated calcium channel alpha subunit Cav3.1)
            (Cav3.1c) (NBR13)
          Length = 2377

 Score = 29.3 bits (64), Expect = 7.9
 Identities = 18/51 (35%), Positives = 24/51 (47%)
 Frame = -3

Query: 462  PAAAATRSHGASCSTS*HAQTTPPRSTNGSGSTSPPRPWRVTSSLPWRRPS 310
            PA+  T S G++   + H   +PP     S  +SP  PW   SS   RR S
Sbjct: 1064 PASRRTSSSGSAEPGAAHEMKSPP-----SARSSPHSPWSAASSWTSRRSS 1109


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 86,552,515
Number of Sequences: 219361
Number of extensions: 1956396
Number of successful extensions: 5861
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 5515
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5852
length of database: 80,573,946
effective HSP length: 105
effective length of database: 57,541,041
effective search space used: 4545742239
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)