>AGAL_COFAR (Q42656) Alpha-galactosidase precursor (EC 3.2.1.22) (Melibiase)|
           (Alpha-D-galactoside galactohydrolase)
          Length = 378

 Score =  245 bits (625), Expect = 1e-64
 Identities = 120/189 (63%), Positives = 135/189 (71%)
 Frame = -2

Query: 748 NSWRXTDDIQDTWKSMTDIADKNNKWASYAGPGGWNDPDMLEVGNGGMTFAEYRAHFSIW 569
           NSWR T DI D+W SMT  AD N+KWASYAGPGGWNDPDMLEVGNGGMT  EYR+HFSIW
Sbjct: 193 NSWRTTGDIDDSWSSMTSRADMNDKWASYAGPGGWNDPDMLEVGNGGMTTTEYRSHFSIW 252

Query: 568 ALMKAPLLIGCDVRNMTSQTIEILSNKEVIQVNQDPLGVQGRRILGQGKGGCREVWAGPL 389
           AL KAPLLIGCD+R+M   T ++LSN EVI VNQD LGVQG ++   G     EVWAGPL
Sbjct: 253 ALAKAPLLIGCDIRSMDGATFQLLSNAEVIAVNQDKLGVQGNKVKTYGD---LEVWAGPL 309

Query: 388 SGNRLAVALWNRCSETVNITMTLPAVGLDGSSAYSVRDLWKHETLSANVVGTFGAQVDMH 209
           SG R+AVALWNR S T  IT     VGL  ++  + RDLW H T   +V G   A VD H
Sbjct: 310 SGKRVAVALWNRGSSTATITAYWSDVGLPSTAVVNARDLWAHST-EKSVKGQISAAVDAH 368

Query: 208 DCKMYIFTP 182
           D KMY+ TP
Sbjct: 369 DSKMYVLTP 377

>AGAL_ORYSA (Q9FXT4) Alpha-galactosidase precursor (EC 3.2.1.22) (Melibiase)|
           (Alpha-D-galactoside galactohydrolase)
          Length = 417

 Score =  242 bits (617), Expect = 1e-63
 Identities = 121/189 (64%), Positives = 137/189 (72%)
 Frame = -2

Query: 748 NSWRXTDDIQDTWKSMTDIADKNNKWASYAGPGGWNDPDMLEVGNGGMTFAEYRAHFSIW 569
           NSWR T DI D W SMT  AD+N++WA+YAGPGGWNDPDMLEVGNGGM+ AEYR+HFSIW
Sbjct: 233 NSWRTTGDIADNWGSMTSRADENDQWAAYAGPGGWNDPDMLEVGNGGMSEAEYRSHFSIW 292

Query: 568 ALMKAPLLIGCDVRNMTSQTIEILSNKEVIQVNQDPLGVQGRRILGQGKGGCREVWAGPL 389
           AL KAPLLIGCDVR+M+ QT  ILSN EVI VNQD LGVQG+++  Q   G  EVWAGPL
Sbjct: 293 ALAKAPLLIGCDVRSMSQQTKNILSNSEVIAVNQDSLGVQGKKV--QSDNGL-EVWAGPL 349

Query: 388 SGNRLAVALWNRCSETVNITMTLPAVGLDGSSAYSVRDLWKHETLSANVVGTFGAQVDMH 209
           S NR AV LWNR S    IT     +GL GS A + RDLW H + +A   G   A V  H
Sbjct: 350 SNNRKAVVLWNRQSYQATITAHWSNIGLAGSVAVTARDLWAHSSFAAQ--GQISASVAPH 407

Query: 208 DCKMYIFTP 182
           DCKMY+ TP
Sbjct: 408 DCKMYVLTP 416

>AGAL_CYATE (P14749) Alpha-galactosidase precursor (EC 3.2.1.22) (Melibiase)|
           (Alpha-D-galactoside galactohydrolase)
          Length = 411

 Score =  242 bits (617), Expect = 1e-63
 Identities = 114/189 (60%), Positives = 134/189 (70%)
 Frame = -2

Query: 748 NSWRXTDDIQDTWKSMTDIADKNNKWASYAGPGGWNDPDMLEVGNGGMTFAEYRAHFSIW 569
           NSWR T DI+D W SMT IAD N+KWASYAGPGGWNDPDMLEVGNGGMT  EYR+HFSIW
Sbjct: 225 NSWRTTGDIEDNWNSMTSIADSNDKWASYAGPGGWNDPDMLEVGNGGMTTEEYRSHFSIW 284

Query: 568 ALMKAPLLIGCDVRNMTSQTIEILSNKEVIQVNQDPLGVQGRRILGQGKGGCREVWAGPL 389
           AL KAPLL+GCD+R M   T E++SN EVI VNQD LGVQG+++         EVWAGPL
Sbjct: 285 ALAKAPLLVGCDIRAMDDTTHELISNAEVIAVNQDKLGVQGKKVKSTND---LEVWAGPL 341

Query: 388 SGNRLAVALWNRCSETVNITMTLPAVGLDGSSAYSVRDLWKHETLSANVVGTFGAQVDMH 209
           S N++AV LWNR S    +T +   +GL   +    RDLW+H T S  V G   A++D H
Sbjct: 342 SDNKVAVILWNRSSSRATVTASWSDIGLQQGTTVDARDLWEHSTQSL-VSGEISAEIDSH 400

Query: 208 DCKMYIFTP 182
            CKMY+ TP
Sbjct: 401 ACKMYVLTP 409

>NAGAB_CHICK (Q90744) Alpha-N-acetylgalactosaminidase (EC 3.2.1.49)|
           (Alpha-galactosidase B)
          Length = 405

 Score =  129 bits (325), Expect = 7e-30
 Identities = 68/176 (38%), Positives = 106/176 (60%), Gaps = 5/176 (2%)
 Frame = -2

Query: 748 NSWRXTDDIQDTWKSMTDIAD----KNNKWASYAGPGGWNDPDMLEVGNGGMTFAEYRAH 581
           N WR  DDIQD+W S+  I D      +    +AGPG WNDPDML +GN G+++ + R+ 
Sbjct: 194 NLWRNYDDIQDSWDSVLSIVDWFFTNQDVLQPFAGPGHWNDPDMLIIGNFGLSYEQSRSQ 253

Query: 580 FSIWALMKAPLLIGCDVRNMTSQTIEILSNKEVIQVNQDPLGVQGRRILGQGKGGCREVW 401
            ++W +M APLL+  D+R ++    +IL N+ +IQ+NQDPLG+QGRRI+ +G     EV+
Sbjct: 254 MALWTIMAAPLLMSTDLRTISPSAKKILQNRLMIQINQDPLGIQGRRIIKEGSH--IEVF 311

Query: 400 AGPLSGNRLAVALWNRCSE-TVNITMTLPAVGLDGSSAYSVRDLWKHETLSANVVG 236
             PLS    A+  ++R ++     T +L  +G    +AY V+D++  + +S    G
Sbjct: 312 LRPLSQAASALVFFSRRTDMPFRYTTSLAKLGFPMGAAYEVQDVYSGKIISGLKTG 367

>NAGAB_BOVIN (Q58DH9) Alpha-N-acetylgalactosaminidase precursor (EC 3.2.1.49)|
           (Alpha-galactosidase B)
          Length = 411

 Score =  120 bits (300), Expect = 6e-27
 Identities = 61/171 (35%), Positives = 101/171 (59%), Gaps = 5/171 (2%)
 Frame = -2

Query: 748 NSWRXTDDIQDTWKSMTDIAD----KNNKWASYAGPGGWNDPDMLEVGNGGMTFAEYRAH 581
           N WR  DDIQD+W+S+  + D      +     AGPG WNDPDML +GN G++F + +A 
Sbjct: 210 NLWRNFDDIQDSWRSVLSVLDWFVTHQDVLQPIAGPGHWNDPDMLLIGNFGLSFEQAQAQ 269

Query: 580 FSIWALMKAPLLIGCDVRNMTSQTIEILSNKEVIQVNQDPLGVQGRRILGQGKGGCREVW 401
            ++W ++ APL +  D+R +++Q ++IL N  +I++NQDPLG+QGRRIL +      EV+
Sbjct: 270 MALWTVLAAPLFMSTDLRTISAQNMDILQNPLMIKINQDPLGIQGRRILKEKSH--IEVY 327

Query: 400 AGPLSGNRLAVALWNRCSE-TVNITMTLPAVGLDGSSAYSVRDLWKHETLS 251
             PL+    A+  ++R  +   +   +L  +    S  Y  +D++  + +S
Sbjct: 328 LRPLASEASAIVFFSRRMDMPYHYHSSLARLNFSSSVVYEAQDVYTGDIIS 378

>AGAL_HUMAN (P06280) Alpha-galactosidase A precursor (EC 3.2.1.22) (Melibiase)|
           (Alpha-D-galactoside galactohydrolase)
           (Alpha-D-galactosidase A) (Agalsidase alfa)
          Length = 429

 Score =  117 bits (294), Expect = 3e-26
 Identities = 62/140 (44%), Positives = 86/140 (61%), Gaps = 8/140 (5%)
 Frame = -2

Query: 748 NSWRXTDDIQDTWKSMTDIADKNNKWASY--------AGPGGWNDPDMLEVGNGGMTFAE 593
           N WR   DI D+WKS+  I D    W S+        AGPGGWNDPDML +GN G+++ +
Sbjct: 224 NHWRNFADIDDSWKSIKSILD----WTSFNQERIVDVAGPGGWNDPDMLVIGNFGLSWNQ 279

Query: 592 YRAHFSIWALMKAPLLIGCDVRNMTSQTIEILSNKEVIQVNQDPLGVQGRRILGQGKGGC 413
                ++WA+M APL +  D+R+++ Q   +L +K+VI +NQDPLG QG ++    +G  
Sbjct: 280 QVTQMALWAIMAAPLFMSNDLRHISPQAKALLQDKDVIAINQDPLGKQGYQL---RQGDN 336

Query: 412 REVWAGPLSGNRLAVALWNR 353
            EVW  PLSG   AVA+ NR
Sbjct: 337 FEVWERPLSGLAWAVAMINR 356

>NAGAB_HUMAN (P17050) Alpha-N-acetylgalactosaminidase precursor (EC 3.2.1.49)|
           (Alpha-galactosidase B)
          Length = 411

 Score =  117 bits (293), Expect = 4e-26
 Identities = 63/171 (36%), Positives = 98/171 (57%), Gaps = 5/171 (2%)
 Frame = -2

Query: 748 NSWRXTDDIQDTWKSMTDI----ADKNNKWASYAGPGGWNDPDMLEVGNGGMTFAEYRAH 581
           N WR  DDIQD+W S+  I     +  +     AGPG WNDPDML +GN G++  + RA 
Sbjct: 210 NLWRNYDDIQDSWWSVLSILNWFVEHQDILQPVAGPGHWNDPDMLLIGNFGLSLEQSRAQ 269

Query: 580 FSIWALMKAPLLIGCDVRNMTSQTIEILSNKEVIQVNQDPLGVQGRRILGQGKGGCREVW 401
            ++W ++ APLL+  D+R +++Q ++IL N  +I++NQDPLG+QGRRI    +    EV+
Sbjct: 270 MALWTVLAAPLLMSTDLRTISAQNMDILQNPLMIKINQDPLGIQGRRI--HKEKSLIEVY 327

Query: 400 AGPLSGNRLAVALWN-RCSETVNITMTLPAVGLDGSSAYSVRDLWKHETLS 251
             PLS    A+  ++ R         +L  +   GS  Y  +D++  + +S
Sbjct: 328 MRPLSNKASALVFFSCRTDMPYRYHSSLGQLNFTGSVIYEAQDVYSGDIIS 378

>NAGAB_MOUSE (Q9QWR8) Alpha-N-acetylgalactosaminidase precursor (EC 3.2.1.49)|
           (Alpha-galactosidase B)
          Length = 415

 Score =  114 bits (286), Expect = 2e-25
 Identities = 54/109 (49%), Positives = 74/109 (67%), Gaps = 4/109 (3%)
 Frame = -2

Query: 748 NSWRXTDDIQDTWKSMTDIAD----KNNKWASYAGPGGWNDPDMLEVGNGGMTFAEYRAH 581
           N WR   DIQD+WKS+  I D      +     AGPG WNDPDML +GN G++F E RA 
Sbjct: 210 NLWRNYKDIQDSWKSVLSILDWFVRHQDVLQPVAGPGHWNDPDMLLIGNFGLSFDESRAQ 269

Query: 580 FSIWALMKAPLLIGCDVRNMTSQTIEILSNKEVIQVNQDPLGVQGRRIL 434
            ++W ++ APLL+  D+R ++ Q ++IL N  +I++NQDPLG+QGRRIL
Sbjct: 270 MALWTVLAAPLLMSTDLRTISPQNMDILQNPLMIKINQDPLGIQGRRIL 318

>AGAL_MOUSE (P51569) Alpha-galactosidase A precursor (EC 3.2.1.22) (Melibiase)|
           (Alpha-D-galactoside galactohydrolase)
           (Alpha-D-galactosidase A)
          Length = 419

 Score =  109 bits (273), Expect = 8e-24
 Identities = 58/135 (42%), Positives = 80/135 (59%), Gaps = 4/135 (2%)
 Frame = -2

Query: 748 NSWRXTDDIQDTWKSMTDIAD----KNNKWASYAGPGGWNDPDMLEVGNGGMTFAEYRAH 581
           N WR  DD+ D+W+S+ +I         +    AGPG WNDPDML +GN G+++ +    
Sbjct: 224 NHWRNFDDVYDSWESIKNILSWTVVYQKEIVEVAGPGSWNDPDMLVIGNFGLSWDQQVTQ 283

Query: 580 FSIWALMKAPLLIGCDVRNMTSQTIEILSNKEVIQVNQDPLGVQGRRILGQGKGGCREVW 401
            ++WA+M APLL+  D+R ++SQ   +L NK+VI +NQDPLG QG       K    EVW
Sbjct: 284 MALWAIMAAPLLMSNDLRQISSQAKALLQNKDVIAINQDPLGKQGYCF---RKENHIEVW 340

Query: 400 AGPLSGNRLAVALWN 356
             PLS    AVA+ N
Sbjct: 341 ERPLSNLAWAVAVRN 355

>NAGAB_RAT (Q66H12) Alpha-N-acetylgalactosaminidase precursor (EC 3.2.1.49)|
           (Alpha-galactosidase B)
          Length = 415

 Score =  108 bits (271), Expect = 1e-23
 Identities = 59/136 (43%), Positives = 84/136 (61%), Gaps = 4/136 (2%)
 Frame = -2

Query: 748 NSWRXTDDIQDTWKSMTDIADKNNKWASY----AGPGGWNDPDMLEVGNGGMTFAEYRAH 581
           N WR   DIQD+WKS+  I D   K        +GPG WNDPDML +GN G++F E RA 
Sbjct: 210 NLWRNYKDIQDSWKSVLSILDWFVKHQDILQPVSGPGHWNDPDMLLIGNFGLSFDESRAQ 269

Query: 580 FSIWALMKAPLLIGCDVRNMTSQTIEILSNKEVIQVNQDPLGVQGRRILGQGKGGCREVW 401
            ++W ++ APL +  D+R ++ Q I+IL N  +I++NQDPLG+QGR I  + K    EV+
Sbjct: 270 MALWTVLAAPLFMSTDLRTISPQNIDILQNPLLIKINQDPLGIQGRLIF-KSKSHI-EVF 327

Query: 400 AGPLSGNRLAVALWNR 353
              LS +  A+  ++R
Sbjct: 328 KRNLSDDASALVFFSR 343

>AGAL_SCHPO (Q9URZ0) Probable alpha-galactosidase precursor (EC 3.2.1.22)|
           (Melibiase) (Alpha-D-galactoside galactohydrolase)
          Length = 436

 Score =  107 bits (268), Expect = 3e-23
 Identities = 75/211 (35%), Positives = 115/211 (54%), Gaps = 34/211 (16%)
 Frame = -2

Query: 748 NSWRXTDDIQDTWK---------------------SMTDIADKNNKWASYAGPG-GWNDP 635
           NSWR + DI DT+                      S+ +I  K +  +S AG   GWND 
Sbjct: 207 NSWRISGDIFDTFSRKDVRCPCETIECFALQGDHCSVMNIISKASFLSSKAGMNSGWNDL 266

Query: 634 DMLEVGNGGMTFAEYRAHFSIWALMKAPLLIGCDVRNMTSQTIEILSNKEVIQVNQDPLG 455
           D LEVGNGGM+F EY+ HF++WA++K+PL++G DV +M+     I+SNKE+I +NQD +G
Sbjct: 267 DSLEVGNGGMSFEEYKTHFTMWAILKSPLILGNDVSSMSPMDKLIVSNKELISINQD-IG 325

Query: 454 VQGRRILGQGKGGCR--EVWAGPLSGNRLAVALWNRCSETVNITMTLPAVGLD--GSSAY 287
                ++ + K G    E+++G LS N   VA+ N  SE + + + L  + +D  G++ +
Sbjct: 326 TNPAALIWKKKYGDEYIELFSGRLSNNDWVVAVLNAASEPLKMGIHLSDIFVDALGNAEH 385

Query: 286 S--VRDLWKH------ETLSANVVGTFGAQV 218
                DLW +      + + AN V + G QV
Sbjct: 386 DWLATDLWNNNVKLVSDRIRAN-VASHGVQV 415

>MEL6_YEAST (P41947) Alpha-galactosidase 6 precursor (EC 3.2.1.22) (Melibiase|
           6) (Alpha-D-galactoside galactohydrolase 6)
          Length = 471

 Score =  102 bits (254), Expect = 1e-21
 Identities = 60/163 (36%), Positives = 86/163 (52%), Gaps = 17/163 (10%)
 Frame = -2

Query: 706 SMTDIADKNNKWASYAGPGGWNDPDMLEVGNGGMTFAEYRAHFSIWALMKAPLLIGCDVR 527
           S+ +I +K       AG GGWND D LEVG G +T  E +AHFS+WA++K+PL+IG DV 
Sbjct: 238 SIMNILNKAAPMGQNAGVGGWNDLDNLEVGVGNLTDDEEKAHFSMWAMVKSPLIIGADVN 297

Query: 526 NMTSQTIEILSNKEVIQVNQDPLGVQGRRI----------LGQGKGGCREVWAGPLSGNR 377
           ++ + +  I S   VI +NQDP G+   R+           GQG+    ++W+GPL    
Sbjct: 298 HLKASSYSIYSQASVIAINQDPKGIPATRVWRYYVSDTDEYGQGE---IQMWSGPLDNGD 354

Query: 376 LAVALWNRCSETVNITMTLPAVGLDG-------SSAYSVRDLW 269
             VAL N  S    +  TL  +  D        +S + + DLW
Sbjct: 355 QVVALLNGGSVARPMNTTLEEIFFDSNLGSKELTSTWDIYDLW 397

>MEL5_YEAST (P41946) Alpha-galactosidase 5 precursor (EC 3.2.1.22) (Melibiase|
           5) (Alpha-D-galactoside galactohydrolase 5)
          Length = 471

 Score =  102 bits (254), Expect = 1e-21
 Identities = 60/163 (36%), Positives = 86/163 (52%), Gaps = 17/163 (10%)
 Frame = -2

Query: 706 SMTDIADKNNKWASYAGPGGWNDPDMLEVGNGGMTFAEYRAHFSIWALMKAPLLIGCDVR 527
           S+ +I +K       AG GGWND D LEVG G +T  E +AHFS+WA++K+PL+IG DV 
Sbjct: 238 SIMNILNKAAPMGQNAGVGGWNDLDNLEVGVGNLTDDEEKAHFSMWAMVKSPLIIGADVN 297

Query: 526 NMTSQTIEILSNKEVIQVNQDPLGVQGRRI----------LGQGKGGCREVWAGPLSGNR 377
           ++ + +  I S   VI +NQDP G+   R+           GQG+    ++W+GPL    
Sbjct: 298 HLKASSYSIYSQASVIAINQDPKGIPATRVWRYYVSDTDEYGQGE---IQMWSGPLDNGD 354

Query: 376 LAVALWNRCSETVNITMTLPAVGLDG-------SSAYSVRDLW 269
             VAL N  S    +  TL  +  D        +S + + DLW
Sbjct: 355 QVVALLNGGSVARPMNTTLEEIFFDSNLGSKELTSTWDIYDLW 397

>MEL_SACMI (Q11129) Alpha-galactosidase precursor (EC 3.2.1.22) (Melibiase)|
           (Alpha-D-galactoside galactohydrolase) (MELj)
          Length = 471

 Score =  100 bits (248), Expect = 6e-21
 Identities = 60/174 (34%), Positives = 93/174 (53%), Gaps = 18/174 (10%)
 Frame = -2

Query: 706 SMTDIADKNNKWASYAGPGGWNDPDMLEVGNGGMTFAEYRAHFSIWALMKAPLLIGCDVR 527
           S+ +I +K       AG GGWND D LEVG G +T  E +AHFS+WA++K+PL+IG DV 
Sbjct: 238 SIMNILNKAAPMGQNAGIGGWNDLDNLEVGVGNLTDDEEKAHFSMWAMVKSPLIIGADVN 297

Query: 526 NMTSQTIEILSNKEVIQVNQDPLGVQGRRILGQ--------GKGGCREVWAGPLSGNRLA 371
           ++   +  I S   VI +NQDP GV   R+           GKG   ++W+ PL      
Sbjct: 298 HLKESSYSIYSQASVIAINQDPKGVPATRVWRHYVSQTDKYGKGEI-QLWSCPLDNGDQV 356

Query: 370 VALWNRCSETVNITMTLPAVGLDG-------SSAYSVRDLWKH---ETLSANVV 239
           +AL N  ++   +  +L  +  D        SS++ + DLW +    T+++N++
Sbjct: 357 IALLNGSNKKRPMNASLEDIFFDSYLGSEELSSSWDIYDLWANRIDNTIASNIL 410

>MEL1_YEAST (P04824) Alpha-galactosidase 1 precursor (EC 3.2.1.22) (Melibiase|
           1) (Alpha-D-galactoside galactohydrolase 1)
          Length = 471

 Score = 99.8 bits (247), Expect = 8e-21
 Identities = 60/177 (33%), Positives = 90/177 (50%), Gaps = 17/177 (9%)
 Frame = -2

Query: 706 SMTDIADKNNKWASYAGPGGWNDPDMLEVGNGGMTFAEYRAHFSIWALMKAPLLIGCDVR 527
           S+ +I +K       AG GGWND D LEVG G +T  E +AHFS+WA++K+PL+IG +V 
Sbjct: 238 SIMNILNKAAPMGQNAGVGGWNDLDNLEVGVGNLTDDEEKAHFSMWAMVKSPLIIGANVN 297

Query: 526 NMTSQTIEILSNKEVIQVNQDPLGVQGRRI----------LGQGKGGCREVWAGPLSGNR 377
           N+ + +  I S   VI +NQD  G+   R+           GQG+    ++W+GPL    
Sbjct: 298 NLKASSYSIYSQASVIAINQDSNGIPATRVWRYYVSDTDEYGQGE---IQMWSGPLDNGD 354

Query: 376 LAVALWNRCSETVNITMTLPAVGLDG-------SSAYSVRDLWKHETLSANVVGTFG 227
             VAL N  S +  +  TL  +  D        +S + + DLW +   ++      G
Sbjct: 355 QVVALLNGGSVSRPMNTTLEEIFFDSNLGSKKLTSTWDIYDLWANRVDNSTASAILG 411

>MEL_SACPS (Q03647) Alpha-galactosidase precursor (EC 3.2.1.22) (Melibiase)|
           (Alpha-D-galactoside galactohydrolase) (MELx)
          Length = 471

 Score = 99.0 bits (245), Expect = 1e-20
 Identities = 62/176 (35%), Positives = 90/176 (51%), Gaps = 20/176 (11%)
 Frame = -2

Query: 706 SMTDIADKNNKWASYAGPGGWNDPDMLEVGNGGMTFAEYRAHFSIWALMKAPLLIGCDVR 527
           S+ +I +K       AG GGWND D LEVG G +T  E +AHFS+WA++K+PL+IG DV 
Sbjct: 238 SIMNILNKAAPMGQNAGIGGWNDLDNLEVGVGNLTDDEEKAHFSMWAMVKSPLVIGADVN 297

Query: 526 NMTSQTIEILSNKEVIQVNQDPLGVQGRRI----------LGQGKGGCREVWAGPLSGNR 377
           ++ + +  I S   VI +NQDP GV   R+           GQG+    + W+GPL    
Sbjct: 298 HLKASSYSIYSQASVIAINQDPKGVPATRVWRHQVPQTDKYGQGE---IQFWSGPLDNGD 354

Query: 376 LAVALWNRCSETVNITMTLPAVGLDG-------SSAYSVRDLWKH---ETLSANVV 239
             +AL N   +   +   L  +  D        SS + + DLW +      SAN++
Sbjct: 355 QVIALLNGGIKPRPMNTNLEEIFFDSYLGFEQLSSNWDIYDLWANRVDNATSANIL 410

>MEL_TORDE (Q9UVD6) Alpha-galactosidase precursor (EC 3.2.1.22) (Melibiase)|
           (Alpha-D-galactoside galactohydrolase) (MELt)
          Length = 474

 Score = 98.6 bits (244), Expect = 2e-20
 Identities = 58/160 (36%), Positives = 84/160 (52%), Gaps = 14/160 (8%)
 Frame = -2

Query: 706 SMTDIADKNNKWASYAGPGGWNDPDMLEVGNGGMTFAEYRAHFSIWALMKAPLLIGCDVR 527
           S+ +I +K       AG GGWND D LEVG G +T  E +AHFS+WA++K+ ++IG DVR
Sbjct: 239 SIMNILNKAAPMGQNAGVGGWNDLDCLEVGVGNLTDDEEKAHFSMWAIVKSAMVIGADVR 298

Query: 526 NMTSQTIEILSNKEVIQVNQDPLGVQGRRI-------LGQGKGGCREVWAGPLSGNRLAV 368
           N+   +  I S   V+ +NQDP G    R+         Q   G  ++W+GPL      V
Sbjct: 299 NLKPSSFSIYSQASVLAINQDPAGAPAIRVWRRYVPETDQHGQGEVQLWSGPLDNGDRVV 358

Query: 367 ALWNRCSETVNITMTLPAVGLDG-------SSAYSVRDLW 269
           AL N  ++   +   L  + +D        SS ++V DLW
Sbjct: 359 ALLNGGAKERPMVAYLEDIFIDSFVGSEELSSTWNVYDLW 398

>MEL_ZYGCI (Q99172) Alpha-galactosidase precursor (EC 3.2.1.22) (Melibiase)|
           (Alpha-D-galactoside galactohydrolase)
          Length = 469

 Score = 97.8 bits (242), Expect = 3e-20
 Identities = 58/167 (34%), Positives = 88/167 (52%), Gaps = 14/167 (8%)
 Frame = -2

Query: 706 SMTDIADKNNKWASYAGPGGWNDPDMLEVGNGGMTFAEYRAHFSIWALMKAPLLIGCDVR 527
           S+ +I +K       A PGGWND DMLEVG G M+ +E  AHFS+WA++K+PL+IG D+ 
Sbjct: 237 SIMNILNKAAPMGQNAAPGGWNDLDMLEVGVGNMSDSEEVAHFSMWAIVKSPLIIGADID 296

Query: 526 NMTSQTIEILSNKEVIQVNQDPLGVQGRRI-------LGQGKGGCREVWAGPLSGNRLAV 368
           ++   ++ + SN  VI +NQD LG    RI         Q   G  ++W+GPL      V
Sbjct: 297 DLKDSSLSVYSNPAVIAINQDVLGTPATRIWKYHVSDKDQYGEGEIQLWSGPLDNGDHVV 356

Query: 367 ALWNRCSETVNITMTLPAVGLDG-------SSAYSVRDLWKHETLSA 248
           AL N  +   ++  +   + +D        S+ + + DLW     +A
Sbjct: 357 ALLNGGNNERSMNASWNDIFIDYLADSDELSNTWGLYDLWARRMSNA 403

>MEL_ZYGMR (Q9P4V4) Alpha-galactosidase precursor (EC 3.2.1.22) (Melibiase)|
           (Alpha-D-galactoside galactohydrolase) (MELr)
          Length = 470

 Score = 97.4 bits (241), Expect = 4e-20
 Identities = 56/161 (34%), Positives = 83/161 (51%), Gaps = 15/161 (9%)
 Frame = -2

Query: 706 SMTDIADKNNKWASYAGPGGWNDPDMLEVGNGGMTFAEYRAHFSIWALMKAPLLIGCDVR 527
           S+ +I +K       A PGGWND DMLEVG G +T  E +AHFS+WA++++PL+IG DV 
Sbjct: 238 SIMNILNKAAPMGQNANPGGWNDLDMLEVGVGNLTDDEEKAHFSMWAMVRSPLIIGADVN 297

Query: 526 NMTSQTIEILSNKEVIQVNQDPLGVQGRRIL--------GQGKGGCREVWAGPLSGNRLA 371
           ++   +  I +   VI +NQDP GV   R+           G+G   + W+GPL      
Sbjct: 298 HLKPSSFSIYAQSPVIAINQDPRGVPATRVWRRQVSDTDAYGRGEV-QFWSGPLENGDQV 356

Query: 370 VALWNRCSETVNITMTLPAVGLDG-------SSAYSVRDLW 269
           +A  N  +    +   L  +  D        +S ++V DLW
Sbjct: 357 IAFLNGGNRMRPMNAGLDDIFFDSHPGAPELNSTWAVYDLW 397

>MEL_SACPA (Q09187) Alpha-galactosidase precursor (EC 3.2.1.22) (Melibiase)|
           (Alpha-D-galactoside galactohydrolase) (MELp)
          Length = 471

 Score = 97.4 bits (241), Expect = 4e-20
 Identities = 56/163 (34%), Positives = 84/163 (51%), Gaps = 17/163 (10%)
 Frame = -2

Query: 706 SMTDIADKNNKWASYAGPGGWNDPDMLEVGNGGMTFAEYRAHFSIWALMKAPLLIGCDVR 527
           S+ +I +K        G GGWND D LEVG G +T  E + HFS+WA++K+PL+IG DV 
Sbjct: 238 SIMNILNKAAPMGQNGGIGGWNDLDNLEVGVGNLTDDEEKTHFSMWAMVKSPLIIGADVN 297

Query: 526 NMTSQTIEILSNKEVIQVNQDPLGVQGRRI----------LGQGKGGCREVWAGPLSGNR 377
           ++ + +  I S   VI +NQDP G+   R+           GQG+    + W+GPL    
Sbjct: 298 HLKASSYSIYSQSSVIAINQDPKGIPATRVWRYYVPQTDKYGQGE---IQFWSGPLENGD 354

Query: 376 LAVALWNRCSETVNITMTLPAVGLDG-------SSAYSVRDLW 269
             +AL N   +   +  TL  +  D        S+++ + DLW
Sbjct: 355 QVIALLNGGMKARPMNATLEDIFFDSYQGSEELSTSWDIYDLW 397

>MEL2_YEAST (P41945) Alpha-galactosidase 2 precursor (EC 3.2.1.22) (Melibiase|
           2) (Alpha-D-galactoside galactohydrolase 2)
          Length = 471

 Score = 96.3 bits (238), Expect = 9e-20
 Identities = 59/177 (33%), Positives = 86/177 (48%), Gaps = 17/177 (9%)
 Frame = -2

Query: 706 SMTDIADKNNKWASYAGPGGWNDPDMLEVGNGGMTFAEYRAHFSIWALMKAPLLIGCDVR 527
           S+ +I +K       AG GGWND D LEV  G +T  E +AHF +WA++K+PL+IG DV 
Sbjct: 238 SIMNILNKAAPMGQNAGVGGWNDLDNLEVRVGNLTDDEEKAHFPMWAMVKSPLIIGADVN 297

Query: 526 NMTSQTIEILSNKEVIQVNQDPLGVQGRRI----------LGQGKGGCREVWAGPLSGNR 377
            +   +  I S   VI +NQDP G+   R+           GQG+    ++W+GPL    
Sbjct: 298 TLKPSSYSIYSQASVIAINQDPKGIPATRVWRYYVSDTDEYGQGE---IQMWSGPLDNGD 354

Query: 376 LAVALWNRCSETVNITMTLPAVGLDG-------SSAYSVRDLWKHETLSANVVGTFG 227
             VAL N  S    +  TL  +  D        +S + + DLW +   ++      G
Sbjct: 355 QVVALLNGGSVPRPMNTTLEEIFFDSNLGSKELTSTWDIYDLWANRVDNSTASAILG 411

>AGAL_ASPNG (P28351) Alpha-galactosidase A precursor (EC 3.2.1.22) (Melibiase)|
          Length = 545

 Score = 77.0 bits (188), Expect = 6e-14
 Identities = 50/153 (32%), Positives = 77/153 (50%), Gaps = 1/153 (0%)
 Frame = -2

Query: 712 WKSMTDIADKNNKWASYAGPGGWNDPDMLEVGNGGMTFAEYRAHFSIWALMKAPLLIGCD 533
           W S+ +  + N   A Y  PG +NDPD L   + G+T  E R+HF++WA   APL+I   
Sbjct: 245 WDSIMNNYNYNTLLARYQRPGYFNDPDFLIPDHPGLTADEKRSHFALWASFSAPLIISAY 304

Query: 532 VRNMTSQTIEILSNKEVIQVNQDPLGVQGRRILGQGKGGCREVWAGPLSGNRLAVALWNR 353
           +  ++   I  L+N+ +I VNQDPL  Q    L         +     +G+RL   L N+
Sbjct: 305 IPALSKDEIAFLTNEALIAVNQDPLAQQA--TLASRDDTLDILTRSLANGDRLLTVL-NK 361

Query: 352 CSETVNITMTLPAVGL-DGSSAYSVRDLWKHET 257
            + TV   + +  +GL +    Y+  DLW  +T
Sbjct: 362 GNTTVTRDIPVQWLGLTETDCTYTAEDLWDGKT 394

>IMD_ARTGO (Q44052) Isomalto-dextranase precursor (EC 3.2.1.94) (Glucan|
           1,6-alpha-isomaltosidase) (Exo-isomaltohydrolase)
          Length = 641

 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 60/217 (27%), Positives = 90/217 (41%), Gaps = 22/217 (10%)
 Frame = -2

Query: 742 WRXTDDIQDTWKSMTDIADKNNKWAS-YAGPGGWN----------DPDMLEVGNGGMTFA 596
           W     ++  W+      D    WA+ + G  GW+          D D +       TFA
Sbjct: 301 WDRLSGMRQNWQ------DAWPNWANPFCGFTGWSHRNGRGQLILDGDFMRAS----TFA 350

Query: 595 EYRAHFSIWALMKA---PLLIGCDVRNMTSQTIEILSNKEVIQVNQDPLGVQGRRILGQG 425
                 ++  LM A   PL I  D          + +NKEV+Q+N D  G+ G+ +    
Sbjct: 351 SDEERKTMMNLMVAAGSPLAIA-DTYQQIGNNAWVYTNKEVLQLNAD--GLVGKPLYRSA 407

Query: 424 KG-----GCREV--WAGPLSGNRLAVALWNRCSETVNITMTLP-AVGLDGSSAYSVRDLW 269
                  G R+   WAG L      VAL+NR S+T  +T T+  A  L  ++  +VRDLW
Sbjct: 408 TPFSKDPGSRDTERWAGQLPDGSWGVALFNR-SDTETVTKTIDFAKDLGLATGGNVRDLW 466

Query: 268 KHETLSANVVGTFGAQVDMHDCKMYIFTPAVGFSTSR 158
           +H  L  +   T  A +  H   ++  TP     T+R
Sbjct: 467 EHRNLGMDSRAT--AALAPHASAIFRVTPPKMHGTTR 501

>SECD_SYNY3 (Q55610) Protein-export membrane protein secD|
          Length = 472

 Score = 33.5 bits (75), Expect = 0.73
 Identities = 15/38 (39%), Positives = 23/38 (60%)
 Frame = -2

Query: 571 WALMKAPLLIGCDVRNMTSQTIEILSNKEVIQVNQDPL 458
           + L+K PL +G D+R     TIE+   KE+ Q++ D L
Sbjct: 20  FVLVKLPLQLGLDLRGGAQLTIEVQPTKEIPQIDNDSL 57

>NDK6_MOUSE (O88425) Nucleoside diphosphate kinase 6 (EC 2.7.4.6) (NDK 6) (NDP|
           kinase 6) (nm23-M6)
          Length = 189

 Score = 30.8 bits (68), Expect = 4.7
 Identities = 20/52 (38%), Positives = 26/52 (50%), Gaps = 3/52 (5%)
 Frame = +3

Query: 78  WKLDD*PKFVSRHADIVRGVALTFFYHRLVEKPTAG-VKMYIL--QSCISTW 224
           WKL+D  +F   H          FFY RLVE  T+G ++ YIL  +  I  W
Sbjct: 51  WKLEDCRRFYREHEG-------RFFYQRLVEFMTSGPIRAYILAHKDAIQLW 95

>CAH5B_MOUSE (Q9QZA0) Carbonic anhydrase 5B, mitochondrial precursor (EC|
           4.2.1.1) (Carbonic anhydrase VB) (Carbonate dehydratase
           VB) (CA-VB)
          Length = 317

 Score = 30.0 bits (66), Expect = 8.0
 Identities = 13/40 (32%), Positives = 22/40 (55%)
 Frame = -3

Query: 309 ALMVRLPILLEICGSMRLYRRTW*ELLEPKSICTTARCTF 190
           A+M  L ++L++  S   +RR W   L P+  C+   CT+
Sbjct: 2   AVMNHLRVILQVSSSTLPWRRCWVPRLVPRRSCSLYTCTY 41

>RPOB_CARHZ (Q3A9Q7) DNA-directed RNA polymerase beta chain (EC 2.7.7.6) (RNAP|
            beta subunit) (Transcriptase beta chain) (RNA polymerase
            beta subunit)
          Length = 1132

 Score = 30.0 bits (66), Expect = 8.0
 Identities = 24/89 (26%), Positives = 38/89 (42%)
 Frame = -2

Query: 541  GCDVRNMTSQTIEILSNKEVIQVNQDPLGVQGRRILGQGKGGCREVWAGPLSGNRLAVAL 362
            G   R +  + +  L +   +++  +PLGV  R  +GQ    C   WA    G  +A  +
Sbjct: 860  GVVARILPEEDMPFLPDGTPVEIVLNPLGVPSRMNIGQIL-ECHLGWAAKALGINVATPI 918

Query: 361  WNRCSETVNITMTLPAVGLDGSSAYSVRD 275
            +N  +E  +I   L   GL       VRD
Sbjct: 919  FNGATEE-DIFEALRKAGLPEDGKIEVRD 946


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 117,186,542
Number of Sequences: 219361
Number of extensions: 2597557
Number of successful extensions: 7310
Number of sequences better than 10.0: 27
Number of HSP's better than 10.0 without gapping: 7026
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7280
length of database: 80,573,946
effective HSP length: 109
effective length of database: 56,663,597
effective search space used: 7932903580
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)