ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | rbags13m07 |
|---|---|
| Clone Library Name | barley_pub |
>SUVH2_ARATH (O22781) Histone-lysine N-methyltransferase, H3 lysine-9, H3| lysine-27, H4 lysine-20 and cytosine specific SUVH2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (H3-K27-HMTase 2) (H4-K20-HMTase 2) (Cytosine-HMTase 2) (Suppr Length = 651 Score = 188 bits (478), Expect = 1e-47 Identities = 83/143 (58%), Positives = 114/143 (79%) Frame = -1 Query: 628 WGVRSLDLIKSGTFICEFSGIVLTHQQSEIVAASGDCLVHPNRFPLRWLDWGDISDVYPE 449 WGVR+LDLI++G FICE++G+V+T Q+EI++ +GD +V+P RF +W +WGD+S VYP+ Sbjct: 507 WGVRTLDLIEAGAFICEYAGVVVTRLQAEILSMNGDVMVYPGRFTDQWRNWGDLSQVYPD 566 Query: 448 YVAPNHPATTDLNFSIDVSRARNVACYFSHSCSPNVFIQFVLFDHYNVSYPHLMIFALEN 269 +V PN+P+ L+FS+DVSR RNVACY SHS PNV +QFVL DH ++ +P +M+FALEN Sbjct: 567 FVRPNYPSLPPLDFSMDVSRMRNVACYISHSKEPNVMVQFVLHDHNHLMFPRVMLFALEN 626 Query: 268 IPPLRELSIDYGMIDEWVGKLTM 200 I PL ELS+DYG+ DE GKL + Sbjct: 627 ISPLAELSLDYGLADEVNGKLAI 649
>SUVH9_ARATH (Q9T0G7) Probable histone-lysine N-methyltransferase, H3 lysine-9| specific SUVH9 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 9) (H3-K9-HMTase 9) (Suppressor of variegation 3-9 homolog protein 9) (Su(var)3-9 homolog protein 9) (Protein SET Length = 650 Score = 174 bits (442), Expect = 1e-43 Identities = 75/144 (52%), Positives = 108/144 (75%), Gaps = 1/144 (0%) Frame = -1 Query: 628 WGVRSLDLIKSGTFICEFSGIVLTHQQSEIVAASGDCLVHPNRFP-LRWLDWGDISDVYP 452 WGVRSLD++ +G FICE++G+ LT +Q+ I+ +GD LV+P RF RW DWGD+S V Sbjct: 505 WGVRSLDVLHAGAFICEYAGVALTREQANILTMNGDTLVYPARFSSARWEDWGDLSQVLA 564 Query: 451 EYVAPNHPATTDLNFSIDVSRARNVACYFSHSCSPNVFIQFVLFDHYNVSYPHLMIFALE 272 ++ P++P ++F++DVS+ RNVACY SHS PNV +QFVL DH ++ +P +M+FA E Sbjct: 565 DFERPSYPDIPPVDFAMDVSKMRNVACYISHSTDPNVIVQFVLHDHNSLMFPRVMLFAAE 624 Query: 271 NIPPLRELSIDYGMIDEWVGKLTM 200 NIPP+ ELS+DYG++D+W KL + Sbjct: 625 NIPPMTELSLDYGVVDDWNAKLAI 648
>SUVH5_ARATH (O82175) Histone-lysine N-methyltransferase, H3 lysine-9 specific| SUVH5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Suppressor of variegation 3-9 homolog protein 5) (Su(var)3-9 homolog protein 5) (Protein SET DOMAIN GR Length = 794 Score = 96.7 bits (239), Expect = 5e-20 Identities = 51/131 (38%), Positives = 74/131 (56%) Frame = -1 Query: 628 WGVRSLDLIKSGTFICEFSGIVLTHQQSEIVAASGDCLVHPNRFPLRWLDWGDISDVYPE 449 WGVRSL+ I G+FICE++G +L +Q+E + + L D GD D Sbjct: 659 WGVRSLESIPIGSFICEYAGELLEDKQAESLTGKDEYL----------FDLGDEDDP--- 705 Query: 448 YVAPNHPATTDLNFSIDVSRARNVACYFSHSCSPNVFIQFVLFDHYNVSYPHLMIFALEN 269 F+I+ ++ N+ + +HSCSPN++ Q VL+DH + PH+M FAL+N Sbjct: 706 -------------FTINAAQKGNIGRFINHSCSPNLYAQDVLYDHEEIRIPHIMFFALDN 752 Query: 268 IPPLRELSIDY 236 IPPL+ELS DY Sbjct: 753 IPPLQELSYDY 763
>SUVH6_ARATH (Q8VZ17) Histone-lysine N-methyltransferase, H3 lysine-9 specific| SUVH6 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 6) (H3-K9-HMTase 6) (Suppressor of variegation 3-9 homolog protein 6) (Su(var)3-9 homolog protein 6) (Protein SET DOMAIN GR Length = 790 Score = 82.8 bits (203), Expect = 8e-16 Identities = 51/133 (38%), Positives = 73/133 (54%), Gaps = 2/133 (1%) Frame = -1 Query: 628 WGVRSLDLIKSGTFICEFSGIVLTHQQSEIVAASGDCLVHPNRFPLRWLDWGDISDVYPE 449 WGVR L I G+FICE+ G +L ++E + + L L G +S++ Sbjct: 628 WGVRCLKSIPIGSFICEYVGELLEDSEAERRIGNDEYLFDIGNRYDNSLAQG-MSELMLG 686 Query: 448 YVAPNHPATTDLN--FSIDVSRARNVACYFSHSCSPNVFIQFVLFDHYNVSYPHLMIFAL 275 A A D + F+ID + NV + +HSCSPN++ Q VL+DH + PH+M FA Sbjct: 687 TQAGRSMAEGDESSGFTIDAASKGNVGRFINHSCSPNLYAQNVLYDHEDSRIPHVMFFAQ 746 Query: 274 ENIPPLRELSIDY 236 +NIPPL+EL DY Sbjct: 747 DNIPPLQELCYDY 759
>SUVH3_ARATH (Q9C5P4) Histone-lysine N-methyltransferase, H3 lysine-9 specific| SUVH3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Suppressor of variegation 3-9 homolog protein 3) (Su(var)3-9 homolog protein 3) (Protein SET DOMAIN GR Length = 669 Score = 73.2 bits (178), Expect = 6e-13 Identities = 47/140 (33%), Positives = 71/140 (50%), Gaps = 7/140 (5%) Frame = -1 Query: 628 WGVRSLDLIKSGTFICEFSGIV-----LTHQQSEIVAASGDCLVHPNRFPLRWLDWGDIS 464 WG+RS D +++G+FICE++G V L Q E D V W Sbjct: 506 WGLRSWDSLRAGSFICEYAGEVKDNGNLRGNQEE------DAYVFDTSRVFNSFKWNYEP 559 Query: 463 DVYPEYVAPNHPATTDLNFSIDVSRAR--NVACYFSHSCSPNVFIQFVLFDHYNVSYPHL 290 ++ E + P +L + +S + NVA + +HSCSPNVF Q V+ + S H+ Sbjct: 560 ELVDEDPSTEVPEEFNLPSPLLISAKKFGNVARFMNHSCSPNVFWQPVIREGNGESVIHI 619 Query: 289 MIFALENIPPLRELSIDYGM 230 FA+ +IPP+ EL+ DYG+ Sbjct: 620 AFFAMRHIPPMAELTYDYGI 639
>SUVH1_ARATH (Q9FF80) Histone-lysine N-methyltransferase, H3 lysine-9 specific| SUVH1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog protein 1) (Su(var)3-9 homolog protein 1) (Protein SET DOMAIN GR Length = 670 Score = 72.0 bits (175), Expect = 1e-12 Identities = 42/135 (31%), Positives = 68/135 (50%), Gaps = 2/135 (1%) Frame = -1 Query: 628 WGVRSLDLIKSGTFICEFSGIVLTHQQSEIVAASGDCLVHPNRF--PLRWLDWGDISDVY 455 WG+RS D I++G+FIC + G + + A+ D P +W ++D Sbjct: 507 WGLRSWDAIRAGSFICIYVGEAKDKSKVQQTMANDDYTFDTTNVYNPFKWNYEPGLADE- 565 Query: 454 PEYVAPNHPATTDLNFSIDVSRARNVACYFSHSCSPNVFIQFVLFDHYNVSYPHLMIFAL 275 + + L I NVA + +HSCSPNVF Q V +++ + + H+ FA+ Sbjct: 566 DACEEMSEESEIPLPLIISAKNVGNVARFMNHSCSPNVFWQPVSYENNSQLFVHVAFFAI 625 Query: 274 ENIPPLRELSIDYGM 230 +IPP+ EL+ DYG+ Sbjct: 626 SHIPPMTELTYDYGV 640
>SUVH8_ARATH (Q9C5P0) Histone-lysine N-methyltransferase, H3 lysine-9 specific| SUVH8 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 8) (H3-K9-HMTase 8) (Suppressor of variegation 3-9 homolog protein 8) (Su(var)3-9 homolog protein 8) (Protein SET DOMAIN GR Length = 755 Score = 72.0 bits (175), Expect = 1e-12 Identities = 48/142 (33%), Positives = 73/142 (51%), Gaps = 9/142 (6%) Frame = -1 Query: 628 WGVRSLDLIKSGTFICEFSGIVLTHQQSEIVAASGDCLVHPNRF--PLRWLDWGDISDVY 455 WG+RS D I++GTFICEF+G+ T ++ V D L +R RW + Sbjct: 593 WGLRSWDPIRAGTFICEFTGVSKTKEE---VEEDDDYLFDTSRIYHSFRW-------NYE 642 Query: 454 PEYVAPN--HPATTDLNFS----IDVSRARNVACYFSHSCSPNVFIQFVLFDHYNVS-YP 296 PE + + + D N I NV + +H+C PNVF Q + +D N Y Sbjct: 643 PELLCEDACEQVSEDANLPTQVLISAKEKGNVGRFMNHNCWPNVFWQPIEYDDNNGHIYV 702 Query: 295 HLMIFALENIPPLRELSIDYGM 230 + +FA+++IPP+ EL+ DYG+ Sbjct: 703 RIGLFAMKHIPPMTELTYDYGI 724
>SUVH7_ARATH (Q9C5P1) Histone-lysine N-methyltransferase, H3 lysine-9 specific| SUVH7 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 7) (H3-K9-HMTase 7) (Suppressor of variegation 3-9 homolog protein 7) (Su(var)3-9 homolog protein 7) (Protein SET DOMAIN GR Length = 693 Score = 71.6 bits (174), Expect = 2e-12 Identities = 48/140 (34%), Positives = 74/140 (52%), Gaps = 7/140 (5%) Frame = -1 Query: 628 WGVRSLDLIKSGTFICEFSGIVLTHQQSEIVAASGDCLVHPNRF--PLRW-----LDWGD 470 WG+RS D I++GTFICEF+G+ T ++ E D L ++ RW L D Sbjct: 531 WGLRSWDPIRAGTFICEFAGLRKTKEEVE---EDDDYLFDTSKIYQRFRWNYEPELLLED 587 Query: 469 ISDVYPEYVAPNHPATTDLNFSIDVSRARNVACYFSHSCSPNVFIQFVLFDHYNVSYPHL 290 + E++ N P I NV + +HSCSPNVF Q + +++ Y + Sbjct: 588 SWEQVSEFI--NLPTQV----LISAKEKGNVGRFMNHSCSPNVFWQPIEYENRGDVYLLI 641 Query: 289 MIFALENIPPLRELSIDYGM 230 +FA+++IPP+ EL+ DYG+ Sbjct: 642 GLFAMKHIPPMTELTYDYGV 661
>SUVH4_ARATH (Q8GZB6) Histone-lysine N-methyltransferase, H3 lysine-9 specific| SUVH4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (Suppressor of variegation 3-9 homolog protein 4) (Su(var)3-9 homolog protein 4) (Protein KRYPTONITE) ( Length = 624 Score = 70.9 bits (172), Expect = 3e-12 Identities = 40/137 (29%), Positives = 67/137 (48%), Gaps = 5/137 (3%) Frame = -1 Query: 628 WGVRSLDLIKSGTFICEFSGIVLTHQQSEIVAASG-----DCLVHPNRFPLRWLDWGDIS 464 W VRS + I +G+ +CE+ G+V + ++ + DC R D++ Sbjct: 458 WAVRSWEYIPAGSPVCEYIGVVRRTADVDTISDNEYIFEIDCQQTMQGLGGRQRRLRDVA 517 Query: 463 DVYPEYVAPNHPATTDLNFSIDVSRARNVACYFSHSCSPNVFIQFVLFDHYNVSYPHLMI 284 V+ + F ID N A + +HSC PN+F+Q VL H ++ +++ Sbjct: 518 VPMNNGVSQSSEDENAPEFCIDAGSTGNFARFINHSCEPNLFVQCVLSSHQDIRLARVVL 577 Query: 283 FALENIPPLRELSIDYG 233 FA +NI P++EL+ DYG Sbjct: 578 FAADNISPMQELTYDYG 594
>SUV9_DROME (P45975) Histone-lysine N-methyltransferase, H3 lysine-9 specific| (EC 2.1.1.43) (Histone H3-K9 methyltransferase) (H3-K9-HMTase) (Protein suppressor of variegation 3-9) Length = 635 Score = 65.9 bits (159), Expect = 1e-10 Identities = 38/131 (29%), Positives = 60/131 (45%) Frame = -1 Query: 628 WGVRSLDLIKSGTFICEFSGIVLTHQQSEIVAASGDCLVHPNRFPLRWLDWGDISDVYPE 449 WGVR+ ++ G F+CE+ G ++T ++ G R L LD+ Sbjct: 490 WGVRAATALRKGEFVCEYIGEIITSDEAN---ERGKAYDDNGRTYLFDLDYN-------- 538 Query: 448 YVAPNHPATTDLNFSIDVSRARNVACYFSHSCSPNVFIQFVLFDHYNVSYPHLMIFALEN 269 D ++ID + N++ + +HSC PN+ + +H NV+ PHL+ F L Sbjct: 539 -------TAQDSEYTIDAANYGNISHFINHSCDPNLAVFPCWIEHLNVALPHLVFFTLRP 591 Query: 268 IPPLRELSIDY 236 I ELS DY Sbjct: 592 IKAGEELSFDY 602
>SUVR5_ARATH (O64827) Histone-lysine N-methyltransferase SUVR5 (EC 2.1.1.43)| (Suppressor of variegation 3-9-related protein 5) (Su(var)3-9-related protein 5) (Protein SET DOMAIN GROUP 6) Length = 203 Score = 57.0 bits (136), Expect = 4e-08 Identities = 36/135 (26%), Positives = 63/135 (46%), Gaps = 3/135 (2%) Frame = -1 Query: 628 WGVRSLDLIKSGTFICEFSGIVLTHQQSEIVA---ASGDCLVHPNRFPLRWLDWGDISDV 458 WG+R+ + I GTF+CE+ G VL Q++ +GDC I D+ Sbjct: 57 WGLRACEHILRGTFVCEYIGEVLDQQEANKRRNQYGNGDCSY--------------ILDI 102 Query: 457 YPEYVAPNHPATTDLNFSIDVSRARNVACYFSHSCSPNVFIQFVLFDHYNVSYPHLMIFA 278 +L+++ID + N++ + +HSCSPN+ V+ + H+ ++A Sbjct: 103 DANINDIGRLMEEELDYAIDATTHGNISRFINHSCSPNLVNHQVIVESMESPLAHIGLYA 162 Query: 277 LENIPPLRELSIDYG 233 +I E++ DYG Sbjct: 163 SMDIAAGEEITRDYG 177
>SUV91_HUMAN (O43463) Histone-lysine N-methyltransferase, H3 lysine-9 specific 1| (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1) Length = 412 Score = 57.0 bits (136), Expect = 4e-08 Identities = 36/133 (27%), Positives = 62/133 (46%) Frame = -1 Query: 628 WGVRSLDLIKSGTFICEFSGIVLTHQQSEIVAASGDCLVHPNRFPLRWLDWGDISDVYPE 449 WGVR+L+ I+ +F+ E+ G ++T +++E G L LD+ + DVY Sbjct: 256 WGVRTLEKIRKNSFVMEYVGEIITSEEAE---RRGQIYDRQGATYLFDLDY--VEDVY-- 308 Query: 448 YVAPNHPATTDLNFSIDVSRARNVACYFSHSCSPNVFIQFVLFDHYNVSYPHLMIFALEN 269 ++D + N++ + +HSC PN+ + V D+ + P + FA Sbjct: 309 --------------TVDAAYYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAFFATRT 354 Query: 268 IPPLRELSIDYGM 230 I EL+ DY M Sbjct: 355 IRAGEELTFDYNM 367
>SUV91_MOUSE (O54864) Histone-lysine N-methyltransferase, H3 lysine-9 specific 1| (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1) (Position-effect variegation 3-9 homolog) Length = 412 Score = 56.2 bits (134), Expect = 8e-08 Identities = 36/133 (27%), Positives = 62/133 (46%) Frame = -1 Query: 628 WGVRSLDLIKSGTFICEFSGIVLTHQQSEIVAASGDCLVHPNRFPLRWLDWGDISDVYPE 449 WGVR+L+ I+ +F+ E+ G ++T +++E G L LD+ + DVY Sbjct: 256 WGVRTLEKIRKNSFVMEYVGEIITSEEAE---RRGQIYDRQGATYLFDLDY--VEDVY-- 308 Query: 448 YVAPNHPATTDLNFSIDVSRARNVACYFSHSCSPNVFIQFVLFDHYNVSYPHLMIFALEN 269 ++D + N++ + +HSC PN+ + V D+ + P + FA Sbjct: 309 --------------TVDAAYYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAFFATRT 354 Query: 268 IPPLRELSIDYGM 230 I EL+ DY M Sbjct: 355 IWAGEELTFDYNM 367
>CLR4_SCHPO (O60016) Histone-lysine N-methyltransferase, H3 lysine-9 specific| (EC 2.1.1.43) (Histone H3-K9 methyltransferase) (H3-K9-HMTase) (Cryptic loci regulator 4) Length = 490 Score = 55.5 bits (132), Expect = 1e-07 Identities = 42/131 (32%), Positives = 65/131 (49%) Frame = -1 Query: 628 WGVRSLDLIKSGTFICEFSGIVLTHQQSEIVAASGDCLVHPNRFPLRWLDWGDISDVYPE 449 WGVRSL +GTFI + G V+T + AA D + + + +L D+ D E Sbjct: 340 WGVRSLRFAPAGTFITCYLGEVITSAE----AAKRD--KNYDDDGITYLFDLDMFDDASE 393 Query: 448 YVAPNHPATTDLNFSIDVSRARNVACYFSHSCSPNVFIQFVLFDHYNVSYPHLMIFALEN 269 Y ++D +V+ +F+HSCSPN+ I + +H + L FA+++ Sbjct: 394 Y-------------TVDAQNYGDVSRFFNHSCSPNIAIYSAVRNHGFRTIYDLAFFAIKD 440 Query: 268 IPPLRELSIDY 236 I PL EL+ DY Sbjct: 441 IQPLEELTFDY 451
>SUV92_MOUSE (Q9EQQ0) Histone-lysine N-methyltransferase, H3 lysine-9 specific 2| (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2) Length = 477 Score = 53.9 bits (128), Expect = 4e-07 Identities = 37/133 (27%), Positives = 61/133 (45%) Frame = -1 Query: 628 WGVRSLDLIKSGTFICEFSGIVLTHQQSEIVAASGDCLVHPNRFPLRWLDWGDISDVYPE 449 WGV++L IK +F+ E+ G V+T +++E D N+ D SD Sbjct: 330 WGVKTLVKIKRMSFVMEYVGEVITSEEAERRGQFYD-----NKGITYLFDLDYESD---- 380 Query: 448 YVAPNHPATTDLNFSIDVSRARNVACYFSHSCSPNVFIQFVLFDHYNVSYPHLMIFALEN 269 F++D +R NV+ + +HSC PN+ + V D+ + P + +F+ Sbjct: 381 ------------EFTVDAARYGNVSHFVNHSCDPNLQVFSVFIDNLDTRLPRIALFSTRT 428 Query: 268 IPPLRELSIDYGM 230 I EL+ DY M Sbjct: 429 INAGEELTFDYQM 441
>SUV92_HUMAN (Q9H5I1) Histone-lysine N-methyltransferase, H3 lysine-9 specific 2| (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2) Length = 410 Score = 53.5 bits (127), Expect = 5e-07 Identities = 37/133 (27%), Positives = 61/133 (45%) Frame = -1 Query: 628 WGVRSLDLIKSGTFICEFSGIVLTHQQSEIVAASGDCLVHPNRFPLRWLDWGDISDVYPE 449 WGV++L IK +F+ E+ G V+T +++E D N+ D SD Sbjct: 263 WGVKTLVKIKRMSFVMEYVGEVITSEEAERRGQFYD-----NKGITYLFDLDYESD---- 313 Query: 448 YVAPNHPATTDLNFSIDVSRARNVACYFSHSCSPNVFIQFVLFDHYNVSYPHLMIFALEN 269 F++D +R NV+ + +HSC PN+ + V D+ + P + +F+ Sbjct: 314 ------------EFTVDAARYGNVSHFVNHSCDPNLQVFNVFIDNLDTRLPRIALFSTRT 361 Query: 268 IPPLRELSIDYGM 230 I EL+ DY M Sbjct: 362 INAGEELTFDYQM 374
>EHMT2_MOUSE (Q9Z148) Histone-lysine N-methyltransferase, H3 lysine-9 specific 3| (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a) Length = 1263 Score = 52.0 bits (123), Expect = 1e-06 Identities = 37/132 (28%), Positives = 58/132 (43%) Frame = -1 Query: 628 WGVRSLDLIKSGTFICEFSGIVLTHQQSEIVAASGDCLVHPNRFPLRWLDWGDISDVYPE 449 WGVR+L I GTFICE+ G +++ +++ V + L LD D +VY Sbjct: 1103 WGVRALQTIPQGTFICEYVGELISDAEAD---------VREDDSYLFDLDNKD-GEVY-- 1150 Query: 448 YVAPNHPATTDLNFSIDVSRARNVACYFSHSCSPNVFIQFVLFDHYNVSYPHLMIFALEN 269 ID N++ + +H C PN+ V H ++ +P + F+ + Sbjct: 1151 --------------CIDARYYGNISRFINHLCDPNIIPVRVFMLHQDLRFPRIAFFSSRD 1196 Query: 268 IPPLRELSIDYG 233 I EL DYG Sbjct: 1197 IRTGEELGFDYG 1208
>EHMT2_HUMAN (Q96KQ7) Histone-lysine N-methyltransferase, H3 lysine-9 specific 3| (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a) Length = 1210 Score = 52.0 bits (123), Expect = 1e-06 Identities = 37/132 (28%), Positives = 58/132 (43%) Frame = -1 Query: 628 WGVRSLDLIKSGTFICEFSGIVLTHQQSEIVAASGDCLVHPNRFPLRWLDWGDISDVYPE 449 WGVR+L I GTFICE+ G +++ +++ V + L LD D +VY Sbjct: 1050 WGVRALQTIPQGTFICEYVGELISDAEAD---------VREDDSYLFDLDNKD-GEVY-- 1097 Query: 448 YVAPNHPATTDLNFSIDVSRARNVACYFSHSCSPNVFIQFVLFDHYNVSYPHLMIFALEN 269 ID N++ + +H C PN+ V H ++ +P + F+ + Sbjct: 1098 --------------CIDARYYGNISRFINHLCDPNIIPVRVFMLHQDLRFPRIAFFSSRD 1143 Query: 268 IPPLRELSIDYG 233 I EL DYG Sbjct: 1144 IRTGEELGFDYG 1155
>SUVHA_ARATH (Q3EC60) Putative histone-lysine N-methyltransferase, H3 lysine-9| specific SUVH10 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 10) (H3-K9-HMTase 10) (Suppressor of variegation 3-9 homolog protein 10) (Su(var)3-9 homolog protein 10) (Protein Length = 312 Score = 51.6 bits (122), Expect = 2e-06 Identities = 24/57 (42%), Positives = 36/57 (63%) Frame = -1 Query: 403 IDVSRARNVACYFSHSCSPNVFIQFVLFDHYNVSYPHLMIFALENIPPLRELSIDYG 233 I ++ NVA + +HSCSPNVF Q + + + ++ FA+++IPPL EL DYG Sbjct: 234 ISAKKSGNVARFMNHSCSPNVFWQSIAREQNGLWCLYIGFFAMKHIPPLTELRYDYG 290
>SUVR4_ARATH (Q8W595) Histone-lysine N-methyltransferase SUVR4 (EC 2.1.1.43)| (Suppressor of variegation 3-9-related protein 4) (Su(var)3-9-related protein 4) (Protein SET DOMAIN GROUP 31) Length = 492 Score = 51.6 bits (122), Expect = 2e-06 Identities = 39/138 (28%), Positives = 62/138 (44%), Gaps = 3/138 (2%) Frame = -1 Query: 628 WGVRSLDLIKSGTFICEFSGIVLTHQQ--SEIVAASGDCLVHPNRFPLRWLDWGDISDVY 455 WG+R+L + GTFICE+ G +LT+ + V +S + +P DWG D+ Sbjct: 315 WGLRTLQDLPKGTFICEYIGEILTNTELYDRNVRSSSERHTYPVTLD---ADWGSEKDLK 371 Query: 454 PEYVAPNHPATTDLNFSIDVSRARNVACYFSHSCSPNVFIQF-VLFDHYNVSYPHLMIFA 278 E +D + NVA + +H C I + + + Y H+ F Sbjct: 372 DEEA-----------LCLDATICGNVARFINHRCEDANMIDIPIEIETPDRHYYHIAFFT 420 Query: 277 LENIPPLRELSIDYGMID 224 L ++ + EL+ DY MID Sbjct: 421 LRDVKAMDELTWDY-MID 437
>EHMT1_HUMAN (Q9H9B1) Histone-lysine N-methyltransferase, H3 lysine-9 specific 5| (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a-like protein 1) (GLP1) Length = 1267 Score = 49.7 bits (117), Expect = 7e-06 Identities = 32/132 (24%), Positives = 55/132 (41%) Frame = -1 Query: 628 WGVRSLDLIKSGTFICEFSGIVLTHQQSEIVAASGDCLVHPNRFPLRWLDWGDISDVYPE 449 WGVRSL I GTF+CE+ G +++ ++++ N+ G++ Sbjct: 1107 WGVRSLQDIPPGTFVCEYVGELISDSEADVREEDSYLFDLDNKD-------GEV------ 1153 Query: 448 YVAPNHPATTDLNFSIDVSRARNVACYFSHSCSPNVFIQFVLFDHYNVSYPHLMIFALEN 269 + ID NV+ + +H C PN+ V H ++ +P + F+ Sbjct: 1154 -------------YCIDARFYGNVSRFINHHCEPNLVPVRVFMAHQDLRFPRIAFFSTRL 1200 Query: 268 IPPLRELSIDYG 233 I +L DYG Sbjct: 1201 IEAGEQLGFDYG 1212
>SETB1_MOUSE (O88974) Histone-lysine N-methyltransferase, H3 lysine-9 specific 4| (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET) Length = 1307 Score = 47.4 bits (111), Expect = 4e-05 Identities = 22/58 (37%), Positives = 34/58 (58%) Frame = -1 Query: 409 FSIDVSRARNVACYFSHSCSPNVFIQFVLFDHYNVSYPHLMIFALENIPPLRELSIDY 236 + ID N+ Y +HSCSPN+F+Q V D +++ +P + FA + I EL+ DY Sbjct: 1224 YIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIRAGTELTWDY 1281 Score = 33.1 bits (74), Expect = 0.69 Identities = 12/24 (50%), Positives = 18/24 (75%) Frame = -1 Query: 628 WGVRSLDLIKSGTFICEFSGIVLT 557 WG+R LD I G+F+C ++G +LT Sbjct: 832 WGIRCLDDIAKGSFVCIYAGKILT 855
>SETB1_HUMAN (Q15047) Histone-lysine N-methyltransferase, H3 lysine-9 specific 4| (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET) Length = 1291 Score = 47.4 bits (111), Expect = 4e-05 Identities = 22/58 (37%), Positives = 34/58 (58%) Frame = -1 Query: 409 FSIDVSRARNVACYFSHSCSPNVFIQFVLFDHYNVSYPHLMIFALENIPPLRELSIDY 236 + ID N+ Y +HSCSPN+F+Q V D +++ +P + FA + I EL+ DY Sbjct: 1208 YIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIRAGTELTWDY 1265 Score = 33.1 bits (74), Expect = 0.69 Identities = 12/24 (50%), Positives = 18/24 (75%) Frame = -1 Query: 628 WGVRSLDLIKSGTFICEFSGIVLT 557 WG+R LD I G+F+C ++G +LT Sbjct: 815 WGIRCLDDIAKGSFVCIYAGKILT 838
>DIM5_NEUCR (Q8X225) Histone-lysine N-methyltransferase, H3 lysine-9 specific| dim-5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase dim-5) (H3-K9-HMTase dim-5) (HKMT) Length = 318 Score = 44.7 bits (104), Expect = 2e-04 Identities = 32/131 (24%), Positives = 58/131 (44%) Frame = -1 Query: 628 WGVRSLDLIKSGTFICEFSGIVLTHQQSEIVAASGDCLVHPNRFPLRWLDWGDISDVYPE 449 WGV+ IK G F+ + G ++T ++++ A + + + D + P Sbjct: 161 WGVKCPVNIKRGQFVDRYLGEIITSEEADRRRAESTIARRKDVYLFALDKFSDPDSLDP- 219 Query: 448 YVAPNHPATTDLNFSIDVSRARNVACYFSHSCSPNVFIQFVLFDHYNVSYPHLMIFALEN 269 + P D + +R + +HSC PN+ I + DH + L +FA+++ Sbjct: 220 -LLAGQPLEVDGEYMSGPTR------FINHSCDPNMAIFARVGDHADKHIHDLALFAIKD 272 Query: 268 IPPLRELSIDY 236 IP EL+ DY Sbjct: 273 IPKGTELTFDY 283
>SETB2_HUMAN (Q96T68) Probable histone-lysine N-methyltransferase, H3 lysine-9| specific (EC 2.1.1.43) (Histone H3-K9 methyltransferase) (H3-K9-HMTase) (SET domain bifurcated 2) (Chronic lymphocytic leukemia deletion region gene 8 protein) Length = 719 Score = 44.3 bits (103), Expect = 3e-04 Identities = 19/59 (32%), Positives = 33/59 (55%) Frame = -1 Query: 409 FSIDVSRARNVACYFSHSCSPNVFIQFVLFDHYNVSYPHLMIFALENIPPLRELSIDYG 233 F +D ++ NV + +HSC PN+ +Q V + +N ++P + F + EL+ DYG Sbjct: 636 FLLDATKEGNVGRFLNHSCCPNLLVQNVFVETHNRNFPLVAFFTNRYVKARTELTWDYG 694 Score = 35.4 bits (80), Expect = 0.14 Identities = 15/29 (51%), Positives = 20/29 (68%) Frame = -1 Query: 628 WGVRSLDLIKSGTFICEFSGIVLTHQQSE 542 WGVR LD I GTF+C +SG +L+ +E Sbjct: 379 WGVRCLDDIDRGTFVCIYSGRLLSRANTE 407
>ASHH1_ARATH (Q84WW6) Histone-lysine N-methyltransferase ASHH1 (EC 2.1.1.43)| (ASH1-homolog protein 1) (Protein SET DOMAIN GROUP 26) Length = 492 Score = 43.9 bits (102), Expect = 4e-04 Identities = 37/140 (26%), Positives = 66/140 (47%), Gaps = 1/140 (0%) Frame = -1 Query: 628 WGVRSLDLIKSGTFICEFSGIVLTHQQSEIVAASGDCLVHPNRFPLRWLDWGDISDVYPE 449 WG+ +L+ IK+G FI E+ G V++ ++++ A + + + D Y Sbjct: 101 WGLVALEEIKAGQFIMEYCGEVISWKEAKKRAQT--------------YETHGVKDAY-- 144 Query: 448 YVAPNHPATTDLNFSIDVSRARNVACYFSHSCSPNVFIQFVLFDHYNV-SYPHLMIFALE 272 + + + +ID ++ ++A + +HSC PN + +NV + IFA E Sbjct: 145 ------IISLNASEAIDATKKGSLARFINHSCRPNCETR-----KWNVLGEVRVGIFAKE 193 Query: 271 NIPPLRELSIDYGMIDEWVG 212 +I P EL+ DY EW G Sbjct: 194 SISPRTELAYDYNF--EWYG 211
>SUVR2_ARATH (Q9FNC7) Histone-lysine N-methyltransferase SUVR2 (EC 2.1.1.43)| (Suppressor of variegation 3-9-related protein 2) (Su(var)3-9-related protein 2) (Protein SET DOMAIN GROUP 18) Length = 717 Score = 42.7 bits (99), Expect = 9e-04 Identities = 35/134 (26%), Positives = 56/134 (41%), Gaps = 1/134 (0%) Frame = -1 Query: 628 WGVRSLDLIKSGTFICEFSGIVLTHQQSEIVAASGDCLVHPNRFPLRWLDWGDISDVYPE 449 WG+R+L+ + G F+CE +G +LT E+ D P W DIS Sbjct: 563 WGLRTLEKLPKGAFVCELAGEILT--IPELFQRISDRPTSPVILDAYW-GSEDISG---- 615 Query: 448 YVAPNHPATTDLNFSIDVSRARNVACYFSHSCSPNVFIQF-VLFDHYNVSYPHLMIFALE 272 D S++ + N++ + +H C I+ V + + Y HL F Sbjct: 616 ---------DDKALSLEGTHYGNISRFINHRCLDANLIEIPVHAETTDSHYYHLAFFTTR 666 Query: 271 NIPPLRELSIDYGM 230 I + EL+ DYG+ Sbjct: 667 EIDAMEELTWDYGV 680
>YNCA_CAEEL (P34544) Hypothetical protein R05D3.11 in chromosome III| Length = 1327 Score = 42.7 bits (99), Expect = 9e-04 Identities = 18/58 (31%), Positives = 33/58 (56%) Frame = -1 Query: 409 FSIDVSRARNVACYFSHSCSPNVFIQFVLFDHYNVSYPHLMIFALENIPPLRELSIDY 236 + ID + N+ + +HSC PNV +Q V++D +++ P + F + + EL+ DY Sbjct: 1242 YVIDAKQRGNLGRFLNHSCDPNVHVQHVMYDTHDLRLPWVAFFTRKYVKAGDELTWDY 1299 Score = 31.6 bits (70), Expect = 2.0 Identities = 13/24 (54%), Positives = 16/24 (66%) Frame = -1 Query: 628 WGVRSLDLIKSGTFICEFSGIVLT 557 WGVR+L I TFIC + G +LT Sbjct: 1087 WGVRALTDIPQSTFICTYVGAILT 1110
>SUVR1_ARATH (Q946J2) Histone-lysine N-methyltransferase SUVR1 (EC 2.1.1.43)| (Suppressor of variegation 3-9-related protein 1) (Su(var)3-9-related protein 1) (Protein SET DOMAIN GROUP 13) Length = 630 Score = 42.0 bits (97), Expect = 0.001 Identities = 31/134 (23%), Positives = 54/134 (40%), Gaps = 1/134 (0%) Frame = -1 Query: 628 WGVRSLDLIKSGTFICEFSGIVLTHQQSEIVAASGDCLVHPNRFPLRWLDWGDISDVYPE 449 WG+R+L+ + G FICE+ G +LT P + + D + + Sbjct: 475 WGLRTLEKLPKGAFICEYIGEILT---------------IPELYQRSFEDKPTLPVILDA 519 Query: 448 YVAPNHPATTDLNFSIDVSRARNVACYFSHSCSPNVFIQF-VLFDHYNVSYPHLMIFALE 272 + D +D N++ + +H C I+ V + + Y HL F Sbjct: 520 HWGSEERLEGDKALCLDGMFYGNISRFLNHRCLDANLIEIPVQVETPDQHYYHLAFFTTR 579 Query: 271 NIPPLRELSIDYGM 230 +I + EL+ DYG+ Sbjct: 580 DIEAMEELAWDYGI 593
>TRX_DROVI (Q24742) Protein trithorax| Length = 3828 Score = 40.0 bits (92), Expect = 0.006 Identities = 21/61 (34%), Positives = 32/61 (52%) Frame = -1 Query: 418 DLNFSIDVSRARNVACYFSHSCSPNVFIQFVLFDHYNVSYPHLMIFALENIPPLRELSID 239 D N +D + N A + +HSC PN + + V + + H++IFAL I EL+ D Sbjct: 3749 DDNLVVDATMRGNAARFINHSCEPNCYSKVVDI----LGHKHIIIFALRRIVQGEELTYD 3804 Query: 238 Y 236 Y Sbjct: 3805 Y 3805
>ATX1_ARATH (Q9C5X4) Histone-lysine N-methyltransferase, H3 lysine-4 specific| ATX1 (EC 2.1.1.43) (H3-K4-HMTase) (Trithorax-homolog protein 1) (TRX-homolog protein 1) (Protein SET DOMAIN GROUP 27) Length = 1062 Score = 38.5 bits (88), Expect = 0.016 Identities = 19/56 (33%), Positives = 31/56 (55%) Frame = -1 Query: 403 IDVSRARNVACYFSHSCSPNVFIQFVLFDHYNVSYPHLMIFALENIPPLRELSIDY 236 ID +R ++A +HSC PN + + + + H++IFA +IP EL+ DY Sbjct: 964 IDATRTGSIAHLINHSCVPNCYSRVITVN----GDEHIIIFAKRHIPKWEELTYDY 1015
>TRX_DROME (P20659) Protein trithorax| Length = 3726 Score = 37.0 bits (84), Expect = 0.048 Identities = 19/61 (31%), Positives = 31/61 (50%) Frame = -1 Query: 418 DLNFSIDVSRARNVACYFSHSCSPNVFIQFVLFDHYNVSYPHLMIFALENIPPLRELSID 239 D N +D + N A + +H C PN + + V + + H++IFA+ I EL+ D Sbjct: 3647 DDNLVVDATMRGNAARFINHCCEPNCYSKVVDI----LGHKHIIIFAVRRIVQGEELTYD 3702 Query: 238 Y 236 Y Sbjct: 3703 Y 3703
>LIN59_CAEEL (O44757) Protein lin-59 (Abnormal cell lineage protein 59)| Length = 1312 Score = 36.6 bits (83), Expect = 0.062 Identities = 26/121 (21%), Positives = 52/121 (42%) Frame = -1 Query: 601 KSGTFICEFSGIVLTHQQSEIVAASGDCLVHPNRFPLRWLDWGDISDVYPEYVAPNHPAT 422 ++G F+CE++G V+T +Q++ A D P +A Sbjct: 659 RAGEFLCEYAGEVITREQAQEKFAQ---------------------DRDPRIIA------ 691 Query: 421 TDLNFSIDVSRARNVACYFSHSCSPNVFIQFVLFDHYNVSYPHLMIFALENIPPLRELSI 242 + +D ++ N+A + HSC PN ++ + + +FAL ++ P E+++ Sbjct: 692 IAAHLFVDATKRSNIARFIKHSCKPNSRLEVWSVN----GFYRAGVFALSDLNPNAEITV 747 Query: 241 D 239 D Sbjct: 748 D 748
>HRX_HUMAN (Q03164) Zinc finger protein HRX (ALL-1) (Trithorax-like protein)| Length = 3969 Score = 36.6 bits (83), Expect = 0.062 Identities = 18/56 (32%), Positives = 29/56 (51%) Frame = -1 Query: 403 IDVSRARNVACYFSHSCSPNVFIQFVLFDHYNVSYPHLMIFALENIPPLRELSIDY 236 +D + N A + +HSC PN + + + D H++IFA+ I EL+ DY Sbjct: 3893 VDATMHGNAARFINHSCEPNCYSRVINID----GQKHIVIFAMRKIYRGEELTYDY 3944
>MLL4_HUMAN (Q9UMN6) Myeloid/lymphoid or mixed-lineage leukemia protein 4| (Trithorax homolog 2) Length = 2715 Score = 36.6 bits (83), Expect = 0.062 Identities = 19/56 (33%), Positives = 29/56 (51%) Frame = -1 Query: 403 IDVSRARNVACYFSHSCSPNVFIQFVLFDHYNVSYPHLMIFALENIPPLRELSIDY 236 +D + N A + +HSC PN F + + + H++IFAL I EL+ DY Sbjct: 2639 VDATMHGNAARFINHSCEPNCFSRVIHVE----GQKHIVIFALRRILRGEELTYDY 2690
>HRX_MOUSE (P55200) Zinc finger protein HRX (ALL-1) (Fragment)| Length = 3866 Score = 36.6 bits (83), Expect = 0.062 Identities = 18/56 (32%), Positives = 29/56 (51%) Frame = -1 Query: 403 IDVSRARNVACYFSHSCSPNVFIQFVLFDHYNVSYPHLMIFALENIPPLRELSIDY 236 +D + N A + +HSC PN + + + D H++IFA+ I EL+ DY Sbjct: 3790 VDATMHGNAARFINHSCEPNCYSRVINID----GQKHIVIFAMRKIYRGEELTYDY 3841
>NSD1_MOUSE (O88491) Histone-lysine N-methyltransferase, H3 lysine-36 and H4| lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor binding SET domain containing protein 1) (NR-binding SET domain containing protein) Length = 2588 Score = 35.8 bits (81), Expect = 0.11 Identities = 33/134 (24%), Positives = 57/134 (42%), Gaps = 1/134 (0%) Frame = -1 Query: 628 WGVRSLDLIKSGTFICEFSGIVLTHQQSEIVAASGDCLVHPNRFPLRWLDWGDISDVYPE 449 WG+R+ IK G F+ E+ G ++ ++ R +R+ DI++ Y Sbjct: 1852 WGLRTKTDIKKGEFVNEYVGELIDEEEC--------------RARIRYAQEHDITNFYM- 1896 Query: 448 YVAPNHPATTDLNFSIDVSRARNVACYFSHSCSPNVFIQFVLFDHYNVS-YPHLMIFALE 272 T D + ID N A + +H C PN Q ++V+ + +FAL Sbjct: 1897 -------LTLDKDRIIDAGPKGNYARFMNHCCQPNCETQ-----KWSVNGDTRVGLFALS 1944 Query: 271 NIPPLRELSIDYGM 230 +I EL+ +Y + Sbjct: 1945 DIKAGTELTFNYNL 1958
>NSD1_HUMAN (Q96L73) Histone-lysine N-methyltransferase, H3 lysine-36 and H4| lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor binding SET domain containing protein 1) (NR-binding SET domain containing protein) (Androgen r Length = 2696 Score = 35.8 bits (81), Expect = 0.11 Identities = 33/134 (24%), Positives = 57/134 (42%), Gaps = 1/134 (0%) Frame = -1 Query: 628 WGVRSLDLIKSGTFICEFSGIVLTHQQSEIVAASGDCLVHPNRFPLRWLDWGDISDVYPE 449 WG+R+ IK G F+ E+ G ++ ++ R +R+ DI++ Y Sbjct: 1954 WGLRTKTDIKKGEFVNEYVGELIDEEEC--------------RARIRYAQEHDITNFYM- 1998 Query: 448 YVAPNHPATTDLNFSIDVSRARNVACYFSHSCSPNVFIQFVLFDHYNVS-YPHLMIFALE 272 T D + ID N A + +H C PN Q ++V+ + +FAL Sbjct: 1999 -------LTLDKDRIIDAGPKGNYARFMNHCCQPNCETQ-----KWSVNGDTRVGLFALS 2046 Query: 271 NIPPLRELSIDYGM 230 +I EL+ +Y + Sbjct: 2047 DIKAGTELTFNYNL 2060
>SUVR3_ARATH (Q9SRV2) Histone-lysine N-methyltransferase SUVR3 (EC 2.1.1.43)| (Suppressor of variegation 3-9-related protein 3) (Su(var)3-9-related protein 3) (Protein SET DOMAIN GROUP 20) Length = 338 Score = 35.8 bits (81), Expect = 0.11 Identities = 22/61 (36%), Positives = 29/61 (47%) Frame = -1 Query: 415 LNFSIDVSRARNVACYFSHSCSPNVFIQFVLFDHYNVSYPHLMIFALENIPPLRELSIDY 236 L +ID +R NVA + +HSC + VL P L FA ++I ELS Y Sbjct: 248 LRINIDATRIGNVARFINHSCDGG-NLSTVLLRSSGALLPRLCFFAAKDIIAEEELSFSY 306 Query: 235 G 233 G Sbjct: 307 G 307
>YL222_MIMIV (Q5UQB9) Hypothetical SET domain-containing protein L222| Length = 314 Score = 35.4 bits (80), Expect = 0.14 Identities = 20/65 (30%), Positives = 35/65 (53%), Gaps = 4/65 (6%) Frame = -1 Query: 409 FSIDVSRARNVACY-FSHSCSPNVFIQFVLFDHYNVSYPHLM---IFALENIPPLRELSI 242 F ID ++ A +HSC+PN + + + YN H++ +F++ NIP E++I Sbjct: 112 FGIDGNKLLTCAIQKINHSCTPNCAVN--ISEKYNFGGTHIVFMELFSINNIPANTEITI 169 Query: 241 DYGMI 227 YG + Sbjct: 170 SYGPV 174
>ATX2_ARATH (Q9MA43) Histone-lysine N-methyltransferase ATX2 (EC 2.1.1.43)| (Trithorax-homolog protein 2) (TRX-homolog protein 2) (Protein SET DOMAIN GROUP 30) Length = 1193 Score = 35.4 bits (80), Expect = 0.14 Identities = 17/56 (30%), Positives = 30/56 (53%) Frame = -1 Query: 403 IDVSRARNVACYFSHSCSPNVFIQFVLFDHYNVSYPHLMIFALENIPPLRELSIDY 236 ID +R ++A +HSC PN + + + + H++IFA ++ EL+ DY Sbjct: 962 IDATRTGSIAHLINHSCEPNCYSRVISVN----GDEHIIIFAKRDVAKWEELTYDY 1013
>MLL2_HUMAN (O14686) Myeloid/lymphoid or mixed-lineage leukemia protein 2| (ALL1-related protein) Length = 5262 Score = 34.7 bits (78), Expect = 0.24 Identities = 19/56 (33%), Positives = 28/56 (50%) Frame = -1 Query: 403 IDVSRARNVACYFSHSCSPNVFIQFVLFDHYNVSYPHLMIFALENIPPLRELSIDY 236 ID + A Y +HSC+PN + V FD + ++I + IP EL+ DY Sbjct: 5186 IDATLTGGPARYINHSCAPNCVAEVVTFDKED----KIIIISSRRIPKGEELTYDY 5237
>MES4_DROME (Q8MT36) Probable histone methyltransferase Mes-4 (Maternal-effect| sterile 4) Length = 1427 Score = 34.3 bits (77), Expect = 0.31 Identities = 21/60 (35%), Positives = 33/60 (55%), Gaps = 1/60 (1%) Frame = -1 Query: 412 NFSIDVSRARNVACYFSHSCSPNVFIQFVLFDHYNVSYPHLM-IFALENIPPLRELSIDY 236 +F ID N+A + +HSC PN Q + V+ H + IFA+++IP EL+ +Y Sbjct: 1296 DFIIDAGPKGNLARFMNHSCEPNCETQ-----KWTVNCIHRVGIFAIKDIPVNSELTFNY 1350
>ASHH4_ARATH (Q9M1X9) Putative histone-lysine N-methyltransferase ASHH4 (EC| 2.1.1.43) (ASH1-homolog protein 4) (Protein SET DOMAIN GROUP 24) Length = 352 Score = 33.9 bits (76), Expect = 0.40 Identities = 35/134 (26%), Positives = 54/134 (40%) Frame = -1 Query: 628 WGVRSLDLIKSGTFICEFSGIVLTHQQSEIVAASGDCLVHPNRFPLRWLDWGDISDVYPE 449 +G+ + + I SG FI E+ G V+ + E + V N F L ++W Sbjct: 123 YGIVADEDINSGEFIIEYVGEVIDDKICEERLWKLNHKVETN-FYLCQINW--------- 172 Query: 448 YVAPNHPATTDLNFSIDVSRARNVACYFSHSCSPNVFIQFVLFDHYNVSYPHLMIFALEN 269 N ID + N + Y +HSCSPN +Q + D + IFA Sbjct: 173 ------------NMVIDATHKGNKSRYINHSCSPNTEMQKWIID----GETRIGIFATRF 216 Query: 268 IPPLRELSIDYGMI 227 I +L+ DY + Sbjct: 217 INKGEQLTYDYQFV 230
>SET1_YEAST (P38827) Histone-lysine N-methyltransferase, H3 lysine-4 specific (EC| 2.1.1.43) (COMPASS component SET1) (SET domain protein 1) Length = 1080 Score = 32.3 bits (72), Expect = 1.2 Identities = 29/131 (22%), Positives = 52/131 (39%) Frame = -1 Query: 628 WGVRSLDLIKSGTFICEFSGIVLTHQQSEIVAASGDCLVHPNRFPLRWLDWGDISDVYPE 449 WG+ +LD I + I E+ G + +E+ R+L G Sbjct: 950 WGLYALDSIAAKEMIIEYVGERIRQPVAEMREK-------------RYLKNG-------- 988 Query: 448 YVAPNHPATTDLNFSIDVSRARNVACYFSHSCSPNVFIQFVLFDHYNVSYPHLMIFALEN 269 + ++ D N ID ++ +A + +H C PN + + ++I+AL + Sbjct: 989 -IGSSYLFRVDENTVIDATKKGGIARFINHCCDPNCTAKIIKVG----GRRRIVIYALRD 1043 Query: 268 IPPLRELSIDY 236 I EL+ DY Sbjct: 1044 IAASEELTYDY 1054
>FOG1_HUMAN (Q8IX07) Zinc finger protein ZFPM1 (Zinc finger protein multitype| 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1) Length = 1004 Score = 32.0 bits (71), Expect = 1.5 Identities = 17/44 (38%), Positives = 25/44 (56%) Frame = +1 Query: 145 ENVTQEN*RRICLTVDTATWLTFQPIHQSFHSQCLAPSRAECSP 276 E V Q+ RRI + AT L++ P H S ++ +P +AE SP Sbjct: 93 EPVVQDGQRRIRARLSLATGLSWGPFHGSVQTRASSPRQAEPSP 136
>SET1_SCHPO (Q9Y7R4) Histone-lysine N-methyltransferase, H3 lysine-4 specific (EC| 2.1.1.43) (Set1 complex component set1) (Set1C component set1) (COMPASS component set1) (SET domain-containing protein 1) (Spset1) Length = 920 Score = 32.0 bits (71), Expect = 1.5 Identities = 17/66 (25%), Positives = 34/66 (51%) Frame = -1 Query: 418 DLNFSIDVSRARNVACYFSHSCSPNVFIQFVLFDHYNVSYPHLMIFALENIPPLRELSID 239 D + +D ++ N+A + +HSC+PN + + + ++I+A +I EL+ D Sbjct: 841 DEDVIVDATKKGNIARFINHSCAPNCIARIIRVE----GKRKIVIYADRDIMHGEELTYD 896 Query: 238 YGMIDE 221 Y +E Sbjct: 897 YKFPEE 902
>CLH_YEAST (P22137) Clathrin heavy chain| Length = 1653 Score = 32.0 bits (71), Expect = 1.5 Identities = 22/73 (30%), Positives = 31/73 (42%) Frame = -1 Query: 520 CLVHPNRFPLRWLDWGDISDVYPEYVAPNHPATTDLNFSIDVSRARNVACYFSHSCSPNV 341 C+VH N P+ WL G + E A D N ++ VA FS P+ Sbjct: 645 CVVHTNALPIDWL-VGYFGKLNVEQSLACLKALMDNNIQANIQTVVQVATKFSDLIGPST 703 Query: 340 FIQFVLFDHYNVS 302 I+ LF+ YN + Sbjct: 704 LIK--LFEDYNAT 714
>SET2_CAEEL (Q18221) Protein set-2| Length = 1507 Score = 31.6 bits (70), Expect = 2.0 Identities = 16/61 (26%), Positives = 31/61 (50%) Frame = -1 Query: 418 DLNFSIDVSRARNVACYFSHSCSPNVFIQFVLFDHYNVSYPHLMIFALENIPPLRELSID 239 DL+ ID ++ N A + +HSC PN + + + + ++I++ I E++ D Sbjct: 1428 DLHHVIDATKRGNFARFINHSCQPNCYAKVLTIE----GEKRIVIYSRTIIKKGEEITYD 1483 Query: 238 Y 236 Y Sbjct: 1484 Y 1484
>SET1A_HUMAN (O15047) Histone-lysine N-methyltransferase, H3 lysine-4 specific| SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A) Length = 1707 Score = 31.6 bits (70), Expect = 2.0 Identities = 16/72 (22%), Positives = 37/72 (51%) Frame = -1 Query: 451 EYVAPNHPATTDLNFSIDVSRARNVACYFSHSCSPNVFIQFVLFDHYNVSYPHLMIFALE 272 E + ++ D + ID ++ N+A + +H C+PN + + + + S ++I++ + Sbjct: 1617 EGIGSSYLFRVDHDTIIDATKCGNLARFINHCCTPNCYAKVITIE----SQKKIVIYSKQ 1672 Query: 271 NIPPLRELSIDY 236 I E++ DY Sbjct: 1673 PIGVDEEITYDY 1684
>MES4_CAEEL (Q9NH52) Probable histone methyltransferase mes-4 (Maternal-effect| sterile protein 4) Length = 898 Score = 31.2 bits (69), Expect = 2.6 Identities = 22/95 (23%), Positives = 41/95 (43%) Frame = -1 Query: 628 WGVRSLDLIKSGTFICEFSGIVLTHQQSEIVAASGDCLVHPNRFPLRWLDWGDISDVYPE 449 +GV + I+ +ICE+ G ++ + + R LD IS + Sbjct: 549 YGVFAKGQIEKDEYICEYVGEIIDKAEKK-----------------RRLDSVSISR---D 588 Query: 448 YVAPNHPATTDLNFSIDVSRARNVACYFSHSCSPN 344 + A ++ ++D +R N++ Y +HSC PN Sbjct: 589 FQANHYMMELHKGLTVDAARYGNISRYINHSCDPN 623
>EZ_DROME (P42124) Polycomb protein E(z) (Protein enhancer of zeste)| Length = 760 Score = 30.8 bits (68), Expect = 3.4 Identities = 20/61 (32%), Positives = 29/61 (47%), Gaps = 2/61 (3%) Frame = -1 Query: 412 NFSIDVSRARNVACYFSHSCSPNVF--IQFVLFDHYNVSYPHLMIFALENIPPLRELSID 239 +F +D +R N + +HS +PN + + V DH + IFA I P EL D Sbjct: 686 DFVVDATRKGNKIRFANHSINPNCYAKVMMVTGDH------RIGIFAKRAIQPGEELFFD 739 Query: 238 Y 236 Y Sbjct: 740 Y 740
>ASHH3_ARATH (Q945S8) Histone-lysine N-methyltransferase ASHH3 (EC 2.1.1.43)| (ASH1-homolog protein 3) (Protein SET DOMAIN GROUP 7) Length = 363 Score = 30.8 bits (68), Expect = 3.4 Identities = 18/59 (30%), Positives = 27/59 (45%) Frame = -1 Query: 403 IDVSRARNVACYFSHSCSPNVFIQFVLFDHYNVSYPHLMIFALENIPPLRELSIDYGMI 227 ID + N + Y +HSC+PN +Q + D + IFA I L+ DY + Sbjct: 181 IDATHKGNKSRYINHSCNPNTQMQKWIID----GETRIGIFATRGIKKGEHLTYDYQFV 235
>MEDEA_ARATH (O65312) Polycomb group protein MEDEA (Maternal embryogenesis| control protein) (Protein FERTILIZATION-INDEPENDENT SEED1) (Protein SET DOMAIN GROUP 5) Length = 689 Score = 30.4 bits (67), Expect = 4.5 Identities = 27/131 (20%), Positives = 50/131 (38%) Frame = -1 Query: 628 WGVRSLDLIKSGTFICEFSGIVLTHQQSEIVAASGDCLVHPNRFPLRWLDWGDISDVYPE 449 WG + D +K ++ E++G ++TH ++ + G I D Sbjct: 556 WGAFTWDSLKKNEYLGEYTGELITHDEAN--------------------ERGRIED---- 591 Query: 448 YVAPNHPATTDLNFSIDVSRARNVACYFSHSCSPNVFIQFVLFDHYNVSYPHLMIFALEN 269 + ++ T + ID R N + +HS PN + + ++ + +FA Sbjct: 592 RIGSSYLFTLNDQLEIDARRKGNEFKFLNHSARPNCYAKLMIVR----GDQRIGLFAERA 647 Query: 268 IPPLRELSIDY 236 I EL DY Sbjct: 648 IEEGEELFFDY 658
>SETD8_DROME (Q9VFK6) Histone-lysine N-methyltransferase, H4 lysine-20 specific| (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (dSET8) Length = 691 Score = 30.0 bits (66), Expect = 5.8 Identities = 16/44 (36%), Positives = 25/44 (56%) Frame = -1 Query: 364 SHSCSPNVFIQFVLFDHYNVSYPHLMIFALENIPPLRELSIDYG 233 +HS + N+ + VL PHL++ A ++I P EL+ DYG Sbjct: 637 NHSRAGNLMTKVVLIKQR----PHLVLLAKDDIEPGEELTYDYG 676
>MDH_HAEIN (P44427) Malate dehydrogenase (EC 1.1.1.37)| Length = 311 Score = 30.0 bits (66), Expect = 5.8 Identities = 11/53 (20%), Positives = 27/53 (50%) Frame = -1 Query: 628 WGVRSLDLIKSGTFICEFSGIVLTHQQSEIVAASGDCLVHPNRFPLRWLDWGD 470 +GV +LD+++S TF+ E G+ ++ ++ + P +++ W + Sbjct: 144 FGVTTLDVLRSETFVAELKGLNVSRTSVPVIGGHSGVTILPLLSQVQYAKWNE 196
>MDH_HAEI8 (Q4QL89) Malate dehydrogenase (EC 1.1.1.37)| Length = 311 Score = 30.0 bits (66), Expect = 5.8 Identities = 11/53 (20%), Positives = 27/53 (50%) Frame = -1 Query: 628 WGVRSLDLIKSGTFICEFSGIVLTHQQSEIVAASGDCLVHPNRFPLRWLDWGD 470 +GV +LD+++S TF+ E G+ ++ ++ + P +++ W + Sbjct: 144 FGVTTLDVLRSETFVAELKGLNVSRTSVPVIGGHSGVTILPLLSQVQYAKWNE 196
>SET2_YEAST (P46995) SET domain protein 2| Length = 733 Score = 29.6 bits (65), Expect = 7.6 Identities = 18/59 (30%), Positives = 32/59 (54%), Gaps = 1/59 (1%) Frame = -1 Query: 403 IDVSRARNVACYFSHSCSPNVFI-QFVLFDHYNVSYPHLMIFALENIPPLRELSIDYGM 230 ID + ++A + +HSCSPN ++ ++V+ D + IFA I E++ DY + Sbjct: 185 IDATIKGSLARFCNHSCSPNAYVNKWVVKDKLRMG-----IFAQRKILKGEEITFDYNV 238
>CUL1_CAEEL (Q17389) Cullin-1 (Abnormal cell lineage protein 19)| Length = 780 Score = 29.6 bits (65), Expect = 7.6 Identities = 16/52 (30%), Positives = 27/52 (51%) Frame = +1 Query: 58 YEITARIGNITSRVTSSSNLLDDPKEKHYENVTQEN*RRICLTVDTATWLTF 213 YE TAR+ + + S +L D KEK + + Q++ L + + +W TF Sbjct: 502 YEYTARLSKMVNDTQVSKDLTADFKEKKADMLGQKSVEFNVLVLSSGSWPTF 553
>MDH_SALTY (P25077) Malate dehydrogenase (EC 1.1.1.37)| Length = 312 Score = 29.3 bits (64), Expect = 10.0 Identities = 12/41 (29%), Positives = 22/41 (53%) Frame = -1 Query: 628 WGVRSLDLIKSGTFICEFSGIVLTHQQSEIVAASGDCLVHP 506 +GV +LD+I+S TF+ E G + T + ++ + P Sbjct: 144 FGVTTLDIIRSNTFVAELKGKLPTEVEVPVIGGHSGVTILP 184
>MDH_SALTI (Q8Z3E0) Malate dehydrogenase (EC 1.1.1.37)| Length = 312 Score = 29.3 bits (64), Expect = 10.0 Identities = 12/41 (29%), Positives = 22/41 (53%) Frame = -1 Query: 628 WGVRSLDLIKSGTFICEFSGIVLTHQQSEIVAASGDCLVHP 506 +GV +LD+I+S TF+ E G + T + ++ + P Sbjct: 144 FGVTTLDIIRSNTFVAELKGKLPTEVEVPVIGGHSGVTILP 184
>MDH_SALPA (Q7WS85) Malate dehydrogenase (EC 1.1.1.37)| Length = 312 Score = 29.3 bits (64), Expect = 10.0 Identities = 12/41 (29%), Positives = 22/41 (53%) Frame = -1 Query: 628 WGVRSLDLIKSGTFICEFSGIVLTHQQSEIVAASGDCLVHP 506 +GV +LD+I+S TF+ E G + T + ++ + P Sbjct: 144 FGVTTLDIIRSNTFVAELKGKLPTEVEVPVIGGHSGVTILP 184
>MDH_SALMU (Q59838) Malate dehydrogenase (EC 1.1.1.37) (Fragment)| Length = 283 Score = 29.3 bits (64), Expect = 10.0 Identities = 12/41 (29%), Positives = 22/41 (53%) Frame = -1 Query: 628 WGVRSLDLIKSGTFICEFSGIVLTHQQSEIVAASGDCLVHP 506 +GV +LD+I+S TF+ E G + T + ++ + P Sbjct: 133 FGVTTLDIIRSNTFVAELKGKLPTEVEVPVIGGHSGVTILP 173
>MDH_PASMU (Q9CN86) Malate dehydrogenase (EC 1.1.1.37)| Length = 311 Score = 29.3 bits (64), Expect = 10.0 Identities = 12/53 (22%), Positives = 25/53 (47%) Frame = -1 Query: 628 WGVRSLDLIKSGTFICEFSGIVLTHQQSEIVAASGDCLVHPNRFPLRWLDWGD 470 +GV +LD+I+S TF+ E + ++ + P +++ +W D Sbjct: 144 FGVTTLDIIRSETFVSELKNLEPARTTVPVIGGHSGVTILPLLSQVQYAEWND 196
>CUBN_HUMAN (O60494) Cubilin precursor (Intrinsic factor-cobalamin receptor)| (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor) Length = 3623 Score = 29.3 bits (64), Expect = 10.0 Identities = 23/93 (24%), Positives = 31/93 (33%), Gaps = 5/93 (5%) Frame = +1 Query: 295 GDKTRCSGQTAQTE*IHWDCNYG*NNKPRSLPLRHQSKSSSLLWQDGS-----EPHTQDI 459 G T C G + NY P+ + S W S E +D Sbjct: 1160 GSSTGCGGNLTTSSGTFISPNY---------PMPYYHSSECYWWLKSSHGSAFELEFKDF 1210 Query: 460 HQRYHPNLTTSKGTCSDAPNNHHWLPLSLTADE 558 H +HPN T D P+++ L L DE Sbjct: 1211 HLEHHPNCTLDYLAVYDGPSSNSHLLTQLCGDE 1243
>ATXR3_ARATH (O23372) Probable histone-lysine N-methyltransferase ATXR3 (EC| 2.1.1.43) (Trithorax-related protein 3) (TRX-related protein 3) (Protein SET DOMAIN GROUP 2) Length = 2351 Score = 29.3 bits (64), Expect = 10.0 Identities = 18/69 (26%), Positives = 29/69 (42%), Gaps = 1/69 (1%) Frame = -1 Query: 403 IDVSRARNVACYFSHSCSPNVFIQFVLFD-HYNVSYPHLMIFALENIPPLRELSIDYGMI 227 +D N A HSC PN + D HY + I+++ I E++ DY + Sbjct: 1819 VDAMHMANYASRICHSCRPNCEAKVTAVDGHYQIG-----IYSVRAIEYGEEITFDYNSV 1873 Query: 226 DEWVGKLTM 200 E L++ Sbjct: 1874 TEVCSLLSL 1882 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 92,666,309 Number of Sequences: 219361 Number of extensions: 1935655 Number of successful extensions: 5140 Number of sequences better than 10.0: 66 Number of HSP's better than 10.0 without gapping: 4961 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5115 length of database: 80,573,946 effective HSP length: 107 effective length of database: 57,102,319 effective search space used: 5767334219 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
