ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
menu 
| Clone Name | rbags13a20 |
|---|---|
| Clone Library Name | barley_pub |
>IDHC_SOYBN (Q06197) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 413 Score = 283 bits (724), Expect = 3e-76 Identities = 138/154 (89%), Positives = 148/154 (96%) Frame = -2 Query: 688 IDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHG 509 IDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVL+CPDGKTIEAEAAHG Sbjct: 254 IDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDGKTIEAEAAHG 313 Query: 508 TVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESG 329 TVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNA+LL+F +KLE AC+G VE+G Sbjct: 314 TVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNAKLLDFTEKLEAACIGVVEAG 373 Query: 328 KMTKDLALLVHGSSKVTRSDYLNTEEFIDAVAAE 227 KMTKDLAL++HG SK++R YLNTEEFIDAVAAE Sbjct: 374 KMTKDLALILHG-SKLSREHYLNTEEFIDAVAAE 406
>IDHP_MEDSA (Q40345) Isocitrate dehydrogenase [NADP], chloroplast precursor (EC| 1.1.1.42) (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) (Fragment) Length = 433 Score = 283 bits (724), Expect = 3e-76 Identities = 139/154 (90%), Positives = 147/154 (95%) Frame = -2 Query: 688 IDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHG 509 IDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVL+CPDGKTIEAEAAHG Sbjct: 274 IDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDGKTIEAEAAHG 333 Query: 508 TVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESG 329 TVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNA LL+F +KLE AC+G VESG Sbjct: 334 TVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNATLLDFTEKLEAACIGVVESG 393 Query: 328 KMTKDLALLVHGSSKVTRSDYLNTEEFIDAVAAE 227 KMTKDLAL++HG SK++R YLNTEEFIDAVAAE Sbjct: 394 KMTKDLALILHG-SKLSREHYLNTEEFIDAVAAE 426
>IDHC_TOBAC (P50218) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 415 Score = 275 bits (703), Expect = 1e-73 Identities = 134/154 (87%), Positives = 144/154 (93%) Frame = -2 Query: 688 IDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHG 509 IDDM AYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVL+CPDGKTIEAEAAHG Sbjct: 253 IDDMAAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDGKTIEAEAAHG 312 Query: 508 TVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESG 329 TVTRH+RVHQKGGETSTNSIASIFAWTRGLAHRA LD+N RLL+F +KLE AC+G VESG Sbjct: 313 TVTRHYRVHQKGGETSTNSIASIFAWTRGLAHRATLDNNERLLDFTEKLEAACIGAVESG 372 Query: 328 KMTKDLALLVHGSSKVTRSDYLNTEEFIDAVAAE 227 KMTKDLAL++HG SK++R YLNTEEFIDAVA E Sbjct: 373 KMTKDLALIIHG-SKLSRDHYLNTEEFIDAVADE 405
>IDHC_SOLTU (P50217) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 416 Score = 274 bits (700), Expect = 2e-73 Identities = 133/154 (86%), Positives = 143/154 (92%) Frame = -2 Query: 688 IDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHG 509 IDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVL+CPDGKTIEAEAAHG Sbjct: 253 IDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDGKTIEAEAAHG 312 Query: 508 TVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESG 329 TVTRH+RVHQKGGETSTNSIASIFAWTRGLAHRA LD+N RLL+F +KLE AC+G VESG Sbjct: 313 TVTRHYRVHQKGGETSTNSIASIFAWTRGLAHRATLDNNERLLDFTEKLEAACIGAVESG 372 Query: 328 KMTKDLALLVHGSSKVTRSDYLNTEEFIDAVAAE 227 KMTKDLAL++ SK++R YLNTEEFIDAVA E Sbjct: 373 KMTKDLALIIIHGSKLSREHYLNTEEFIDAVADE 406
>IDHC_MICOH (Q9Z2K8) Isocitrate dehydrogenase [NADP] cytoplasmic (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 414 Score = 234 bits (596), Expect = 2e-61 Identities = 110/149 (73%), Positives = 129/149 (86%) Frame = -2 Query: 688 IDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHG 509 IDDMVA A+KSEGG++WACKNYDGDVQSD +AQG+GSLG+MTSVL+CPDGKT+EAEAAHG Sbjct: 251 IDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDGKTVEAEAAHG 310 Query: 508 TVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESG 329 TVTRH+R+HQKG ETSTN IASIFAW+RGLAHRA+LD+N L FA+ LEE C+ T+E+G Sbjct: 311 TVTRHYRMHQKGQETSTNPIASIFAWSRGLAHRARLDNNTELSFFAKALEEVCIETIEAG 370 Query: 328 KMTKDLALLVHGSSKVTRSDYLNTEEFID 242 MTKDLA + G V RSDYLNT EF+D Sbjct: 371 FMTKDLAACIKGLPNVQRSDYLNTFEFMD 399
>IDHC_MICME (Q9Z2K9) Isocitrate dehydrogenase [NADP] cytoplasmic (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 414 Score = 234 bits (596), Expect = 2e-61 Identities = 110/149 (73%), Positives = 129/149 (86%) Frame = -2 Query: 688 IDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHG 509 IDDMVA A+KSEGG++WACKNYDGDVQSD +AQG+GSLG+MTSVL+CPDGKT+EAEAAHG Sbjct: 251 IDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDGKTVEAEAAHG 310 Query: 508 TVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESG 329 TVTRH+R+HQKG ETSTN IASIFAW+RGLAHRA+LD+N L FA+ LEE C+ T+E+G Sbjct: 311 TVTRHYRMHQKGQETSTNPIASIFAWSRGLAHRARLDNNTELSFFAKALEEVCIETIEAG 370 Query: 328 KMTKDLALLVHGSSKVTRSDYLNTEEFID 242 MTKDLA + G V RSDYLNT EF+D Sbjct: 371 FMTKDLAACIKGLPNVQRSDYLNTFEFMD 399
>IDHC_RAT (P41562) Isocitrate dehydrogenase [NADP] cytoplasmic (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 414 Score = 232 bits (592), Expect = 7e-61 Identities = 110/149 (73%), Positives = 128/149 (85%) Frame = -2 Query: 688 IDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHG 509 IDDMVA A+KSEGG++WACKNYDGDVQSD +AQG+GSLG+MTSVL+CPDGKT+EAEAAHG Sbjct: 251 IDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDGKTVEAEAAHG 310 Query: 508 TVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESG 329 TVTRH+R++QKG ETSTN IASIFAW+RGLAHRAKLD+N L FA LEE C+ T+E+G Sbjct: 311 TVTRHYRMYQKGQETSTNPIASIFAWSRGLAHRAKLDNNTELSFFANALEEVCIETIEAG 370 Query: 328 KMTKDLALLVHGSSKVTRSDYLNTEEFID 242 MTKDLA + G V RSDYLNT EF+D Sbjct: 371 FMTKDLAACIKGLPNVQRSDYLNTFEFMD 399
>IDHC_MOUSE (O88844) Isocitrate dehydrogenase [NADP] cytoplasmic (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 414 Score = 231 bits (590), Expect = 1e-60 Identities = 109/149 (73%), Positives = 129/149 (86%) Frame = -2 Query: 688 IDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHG 509 IDDMVA A+KSEGG++WACKNYDGDVQSD +AQG+GSLG+MTSVL+CPDGKT+EAEAAHG Sbjct: 251 IDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDGKTVEAEAAHG 310 Query: 508 TVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESG 329 TVTRH+R++QKG ETSTN IASIFAW+RGLAHRAKLD+N L FA+ LE+ C+ T+E+G Sbjct: 311 TVTRHYRMYQKGQETSTNPIASIFAWSRGLAHRAKLDNNTELSFFAKALEDVCIETIEAG 370 Query: 328 KMTKDLALLVHGSSKVTRSDYLNTEEFID 242 MTKDLA + G V RSDYLNT EF+D Sbjct: 371 FMTKDLAACIKGLPNVQRSDYLNTFEFMD 399
>IDHC_HUMAN (O75874) Isocitrate dehydrogenase [NADP] cytoplasmic (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 414 Score = 230 bits (586), Expect = 4e-60 Identities = 110/149 (73%), Positives = 127/149 (85%) Frame = -2 Query: 688 IDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHG 509 IDDMVA A+KSEGG++WACKNYDGDVQSD +AQG+GSLG+MTSVL+CPDGKT+EAEAAHG Sbjct: 251 IDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHG 310 Query: 508 TVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESG 329 TVTRH+R++QKG ETSTN IASIFAWTRGLAHRAKLD+N L FA LEE + T+E+G Sbjct: 311 TVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAG 370 Query: 328 KMTKDLALLVHGSSKVTRSDYLNTEEFID 242 MTKDLA + G V RSDYLNT EF+D Sbjct: 371 FMTKDLAACIKGLPNVQRSDYLNTFEFMD 399
>IDHP_PIG (P33198) Isocitrate dehydrogenase [NADP], mitochondrial precursor| (EC 1.1.1.42) (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) (ICD-M) (Fragment) Length = 421 Score = 229 bits (584), Expect = 6e-60 Identities = 113/152 (74%), Positives = 125/152 (82%), Gaps = 1/152 (0%) Frame = -2 Query: 688 IDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHG 509 IDDMVA LKS GG+VWACKNYDGDVQSD LAQGFGSLGLMTSVL+CPDGKTIEAEAAHG Sbjct: 259 IDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHG 318 Query: 508 TVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESG 329 TVTRH+R HQKG TSTN IASIFAWTRGL HR KLD N L+ FAQ LE+ CV TVESG Sbjct: 319 TVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEKVCVETVESG 378 Query: 328 KMTKDLALLVHGSSKVTRSD-YLNTEEFIDAV 236 MTKDLA +HG S V ++ +LNT +F+D + Sbjct: 379 AMTKDLAGCIHGLSNVKLNEHFLNTSDFLDTI 410
>IDHP_BOVIN (Q04467) Isocitrate dehydrogenase [NADP], mitochondrial precursor| (EC 1.1.1.42) (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) (ICD-M) Length = 452 Score = 229 bits (584), Expect = 6e-60 Identities = 113/152 (74%), Positives = 125/152 (82%), Gaps = 1/152 (0%) Frame = -2 Query: 688 IDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHG 509 IDDMVA LKS GG+VWACKNYDGDVQSD LAQGFGSLGLMTSVL+CPDGKTIEAEAAHG Sbjct: 290 IDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHG 349 Query: 508 TVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESG 329 TVTRH+R HQKG TSTN IASIFAWTRGL HR KLD N L+ FAQ LE+ CV TVESG Sbjct: 350 TVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEKVCVETVESG 409 Query: 328 KMTKDLALLVHGSSKVTRSD-YLNTEEFIDAV 236 MTKDLA +HG S V ++ +LNT +F+D + Sbjct: 410 AMTKDLAGCIHGLSNVKLNEHFLNTSDFLDTI 441
>IDHP_HUMAN (P48735) Isocitrate dehydrogenase [NADP], mitochondrial precursor| (EC 1.1.1.42) (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) (ICD-M) Length = 452 Score = 229 bits (583), Expect = 8e-60 Identities = 113/152 (74%), Positives = 125/152 (82%), Gaps = 1/152 (0%) Frame = -2 Query: 688 IDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHG 509 IDDMVA LKS GG+VWACKNYDGDVQSD LAQGFGSLGLMTSVL+CPDGKTIEAEAAHG Sbjct: 290 IDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHG 349 Query: 508 TVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESG 329 TVTRH+R HQKG TSTN IASIFAWTRGL HR KLD N L+ FAQ LE+ CV TVESG Sbjct: 350 TVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVCVETVESG 409 Query: 328 KMTKDLALLVHGSSKVTRSD-YLNTEEFIDAV 236 MTKDLA +HG S V ++ +LNT +F+D + Sbjct: 410 AMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTI 441
>IDH_MYCTU (P65097) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 409 Score = 213 bits (543), Expect = 3e-55 Identities = 106/152 (69%), Positives = 121/152 (79%) Frame = -2 Query: 688 IDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHG 509 IDDMVA LK EGGYVWACKNYDGDVQSD +AQG+GSLGLMTSVLM DGKT+EAEAAHG Sbjct: 254 IDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMTADGKTVEAEAAHG 313 Query: 508 TVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESG 329 TVTRH+R +Q G TSTN IASIFAWTRGL HR KLD +++FA KLE + TVESG Sbjct: 314 TVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAHKLESVVIATVESG 373 Query: 328 KMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 233 KMTKDLA+L+ D+LN+EEF+DA+A Sbjct: 374 KMTKDLAILIG-----PEQDWLNSEEFLDAIA 400
>IDH_MYCBO (P65098) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 409 Score = 213 bits (543), Expect = 3e-55 Identities = 106/152 (69%), Positives = 121/152 (79%) Frame = -2 Query: 688 IDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHG 509 IDDMVA LK EGGYVWACKNYDGDVQSD +AQG+GSLGLMTSVLM DGKT+EAEAAHG Sbjct: 254 IDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMTADGKTVEAEAAHG 313 Query: 508 TVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESG 329 TVTRH+R +Q G TSTN IASIFAWTRGL HR KLD +++FA KLE + TVESG Sbjct: 314 TVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAHKLESVVIATVESG 373 Query: 328 KMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 233 KMTKDLA+L+ D+LN+EEF+DA+A Sbjct: 374 KMTKDLAILIG-----PEQDWLNSEEFLDAIA 400
>IDHP_MOUSE (P54071) Isocitrate dehydrogenase [NADP], mitochondrial precursor| (EC 1.1.1.42) (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) (ICD-M) Length = 523 Score = 213 bits (543), Expect = 3e-55 Identities = 108/152 (71%), Positives = 120/152 (78%), Gaps = 1/152 (0%) Frame = -2 Query: 688 IDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHG 509 IDDMVA LKS GG+VWACKNYDGDVQSD LA FGSLGLMTSVL+CPDGKTIEAEAAHG Sbjct: 362 IDDMVAQVLKSSGGFVWACKNYDGDVQSDILASRFGSLGLMTSVLVCPDGKTIEAEAAHG 421 Query: 508 TVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESG 329 TVTRH+R HQKG TST IASIFAWTRGL HR KLD N L+ FAQ E+ CV TVE G Sbjct: 422 TVTRHYREHQKGRPTSTKGIASIFAWTRGLEHRGKLDGNQDLIRFAQTREKVCVQTVE-G 480 Query: 328 KMTKDLALLVHGSSKVTRSD-YLNTEEFIDAV 236 MTKDLA +HG S V ++ +LNT +F+D + Sbjct: 481 AMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTI 512
>IDH1_CANTR (O13285) Isocitrate dehydrogenase [NADP], mitochondrial precursor| (EC 1.1.1.42) (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) (CtIDP1) Length = 430 Score = 201 bits (511), Expect = 2e-51 Identities = 105/153 (68%), Positives = 121/153 (79%), Gaps = 1/153 (0%) Frame = -2 Query: 688 IDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHG 509 IDDMVA +KS+GG+V A KNYDGDVQSD +AQGFGSLGLMTS LM PDGK EAEAAHG Sbjct: 276 IDDMVAQMIKSKGGFVMALKNYDGDVQSDIVAQGFGSLGLMTSALMTPDGKAYEAEAAHG 335 Query: 508 TVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESG 329 TVTRH+R HQ+G ETSTNSIASIFAWTRGLA R KLD+ +++FA KLE+A + TVE Sbjct: 336 TVTRHYRQHQQGKETSTNSIASIFAWTRGLAQRGKLDETPDVVDFASKLEQATIDTVEVD 395 Query: 328 K-MTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 233 + MTKDLAL + K RS Y+ T EF+DAVA Sbjct: 396 RIMTKDLALAM---GKTDRSAYVTTTEFLDAVA 425
>IDHC_YEAST (P41939) Isocitrate dehydrogenase [NADP] cytoplasmic (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 412 Score = 201 bits (510), Expect = 2e-51 Identities = 106/152 (69%), Positives = 121/152 (79%), Gaps = 1/152 (0%) Frame = -2 Query: 688 IDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHG 509 IDDMVA LKS+GGY+ A KNYDGDV+SD +AQGFGSLGLMTSVL+ PDGKT E+EAAHG Sbjct: 251 IDDMVAQMLKSKGGYIIAMKNYDGDVESDIVAQGFGSLGLMTSVLITPDGKTFESEAAHG 310 Query: 508 TVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTV-ES 332 TVTRHFR HQ+G ETSTNSIASIFAWTRG+ R KLD+ +++F Q LE A V TV E Sbjct: 311 TVTRHFRQHQQGKETSTNSIASIFAWTRGIIQRGKLDNTPDVVKFGQILESATVNTVQED 370 Query: 331 GKMTKDLALLVHGSSKVTRSDYLNTEEFIDAV 236 G MTKDLAL++ K RS Y+ TEEFIDAV Sbjct: 371 GIMTKDLALIL---GKSERSAYVTTEEFIDAV 399
>IDH_SPHYA (P50215) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 406 Score = 199 bits (507), Expect = 5e-51 Identities = 98/151 (64%), Positives = 118/151 (78%) Frame = -2 Query: 688 IDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHG 509 IDDMVA ALK G +VWACKNYDGDVQSD +AQGFGSLGLMTSVL+ PDGKT+EAEAAHG Sbjct: 249 IDDMVASALKWSGKFVWACKNYDGDVQSDTVAQGFGSLGLMTSVLLSPDGKTVEAEAAHG 308 Query: 508 TVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESG 329 TVTRH+R HQ+G TSTN IASIFAWT+GL+ R K DD +++FA+ LE+ C+ TVE G Sbjct: 309 TVTRHYRQHQQGKATSTNPIASIFAWTQGLSFRGKFDDTPDVVKFAETLEQVCIKTVEGG 368 Query: 328 KMTKDLALLVHGSSKVTRSDYLNTEEFIDAV 236 MTKDLALL+ ++ TE+F +A+ Sbjct: 369 AMTKDLALLIGPDQA-----WMTTEQFFEAI 394
>IDHH_YEAST (P53982) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 420 Score = 199 bits (505), Expect = 9e-51 Identities = 102/153 (66%), Positives = 121/153 (79%), Gaps = 1/153 (0%) Frame = -2 Query: 688 IDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHG 509 IDDMVA LKS+GG++ A KNYDGDVQSD +AQGFGSLGLMTS+L+ PDGKT E+EAAHG Sbjct: 251 IDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGKTFESEAAHG 310 Query: 508 TVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVE-S 332 TVTRHFR HQ+G ETSTNSIASIFAWTR + R KLD+ +++F LE+A + TV+ Sbjct: 311 TVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEKATLDTVQVG 370 Query: 331 GKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 233 GKMTKDLAL++ K RS Y+ TEEFID VA Sbjct: 371 GKMTKDLALML---GKTNRSSYVTTEEFIDEVA 400
>IDH2_CANTR (O13294) Isocitrate dehydrogenase [NADP] peroxisomal (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (PS-NADP-IDH) (CtIDP2) Length = 410 Score = 199 bits (505), Expect = 9e-51 Identities = 103/153 (67%), Positives = 119/153 (77%), Gaps = 1/153 (0%) Frame = -2 Query: 688 IDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHG 509 IDDMVA LKS+GGY+ A KNYDGDVQSD +AQGFGSLGLMTSVL+ PDGK E+EAAHG Sbjct: 252 IDDMVAQMLKSKGGYIIAMKNYDGDVQSDIVAQGFGSLGLMTSVLVTPDGKAFESEAAHG 311 Query: 508 TVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESG 329 TVTRH+R HQ+G ETSTNSIASI+AWTRGL R KLDD +++FA++LE+A + TV Sbjct: 312 TVTRHYRQHQQGKETSTNSIASIYAWTRGLIQRGKLDDTPEVVKFAEELEKAVIETVSKD 371 Query: 328 K-MTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 233 MTKDLAL K RS Y+ TEEFID VA Sbjct: 372 NIMTKDLALT---QGKTDRSSYVTTEEFIDGVA 401
>IDHP_SCHPO (O14254) Probable isocitrate dehydrogenase [NADP], mitochondrial| precursor (EC 1.1.1.42) (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 418 Score = 197 bits (501), Expect = 3e-50 Identities = 100/154 (64%), Positives = 120/154 (77%) Frame = -2 Query: 688 IDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHG 509 IDDMVA A+KS GG+VWACKNYDGDV SD +AQ +GSLGLMTSVL+ P+G+T E+EAAHG Sbjct: 261 IDDMVAQAIKSNGGFVWACKNYDGDVMSDVVAQAYGSLGLMTSVLIHPNGRTFESEAAHG 320 Query: 508 TVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESG 329 TV RH+ + KG +TSTNSIASIFAWTRGLAHR +LD N RL++FA LE ACV VE G Sbjct: 321 TVQRHYMQYLKGKKTSTNSIASIFAWTRGLAHRGRLDGNERLVKFANALEHACVRCVEKG 380 Query: 328 KMTKDLALLVHGSSKVTRSDYLNTEEFIDAVAAE 227 MTKDL LL + + Y++T EF+DAV +E Sbjct: 381 IMTKDLYLL-----SKSPNGYVDTFEFLDAVKSE 409
>IDHP_YEAST (P21954) Isocitrate dehydrogenase [NADP], mitochondrial precursor| (EC 1.1.1.42) (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 428 Score = 189 bits (481), Expect = 5e-48 Identities = 99/152 (65%), Positives = 118/152 (77%), Gaps = 1/152 (0%) Frame = -2 Query: 688 IDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHG 509 IDDMVA +KS+GG++ A KNYDGDVQSD +AQGFGSLGLMTS+L+ PDGKT E+EAAHG Sbjct: 268 IDDMVAQMIKSKGGFIMALKNYDGDVQSDIVAQGFGSLGLMTSILVTPDGKTFESEAAHG 327 Query: 508 TVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTV-ES 332 TVTRH+R +QKG ETSTNSIASIFAW+RGL R +LD+ L +FA LE A + TV + Sbjct: 328 TVTRHYRKYQKGEETSTNSIASIFAWSRGLLKRGELDNTPALCKFANILESATLNTVQQD 387 Query: 331 GKMTKDLALLVHGSSKVTRSDYLNTEEFIDAV 236 G MTKDLAL + RS Y+ TEEF+DAV Sbjct: 388 GIMTKDLALACGNNE---RSAYVTTEEFLDAV 416
>IDHP_ASPNG (P79089) Isocitrate dehydrogenase [NADP], mitochondrial precursor| (EC 1.1.1.42) (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 498 Score = 181 bits (460), Expect = 1e-45 Identities = 94/152 (61%), Positives = 113/152 (74%), Gaps = 1/152 (0%) Frame = -2 Query: 688 IDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHG 509 IDDMVA +KSEGG+V A KNYDGDVQSD +AQGFGSLGLMTS L+ P G+ E+EAAHG Sbjct: 338 IDDMVAQMIKSEGGFVMALKNYDGDVQSDIVAQGFGSLGLMTSTLVTPTGEAFESEAAHG 397 Query: 508 TVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTV-ES 332 TVTRH+R HQKG ETSTN IASIFAWTRGL R KLD+ ++ FA++LE AC+ V + Sbjct: 398 TVTRHYREHQKGRETSTNPIASIFAWTRGLIQRGKLDETPDVVTFAEELERACIEVVNDE 457 Query: 331 GKMTKDLALLVHGSSKVTRSDYLNTEEFIDAV 236 G MTKDLAL + R ++ T E++ AV Sbjct: 458 GIMTKDLAL---ACGRKEREAWVTTREYMAAV 486
>LEU3_CAMJR (Q5HS77) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 358 Score = 42.0 bits (97), Expect = 0.002 Identities = 41/137 (29%), Positives = 55/137 (40%), Gaps = 1/137 (0%) Frame = -2 Query: 643 VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTI-EAEAAHGTVTRHFRVHQKGGE 467 V C N GD+ SD LA GSLGL++S + G + E H + Sbjct: 236 VMLCSNLFGDILSDELAAINGSLGLLSSASLNDKGFGLYEPAGGSAPDIAHLNI------ 289 Query: 466 TSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSS 287 N IA I + L + K + + AQ +E A + GKMTKDL Sbjct: 290 --ANPIAQILSAALMLKYSFKEE------QAAQDIENAISLALAQGKMTKDL-------- 333 Query: 286 KVTRSDYLNTEEFIDAV 236 YLNT+E D + Sbjct: 334 --NAKSYLNTDEMGDCI 348
>LEU3_CAMJE (Q9PLW0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 358 Score = 42.0 bits (97), Expect = 0.002 Identities = 41/137 (29%), Positives = 55/137 (40%), Gaps = 1/137 (0%) Frame = -2 Query: 643 VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTI-EAEAAHGTVTRHFRVHQKGGE 467 V C N GD+ SD LA GSLGL++S + G + E H + Sbjct: 236 VMLCSNLFGDILSDELAAINGSLGLLSSASLNDKGFGLYEPAGGSAPDIAHLNI------ 289 Query: 466 TSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSS 287 N IA I + L + K + + AQ +E A + GKMTKDL Sbjct: 290 --ANPIAQILSAALMLKYSFKEE------QAAQDIENAISLALAQGKMTKDL-------- 333 Query: 286 KVTRSDYLNTEEFIDAV 236 YLNT+E D + Sbjct: 334 --NAKSYLNTDEMGDCI 348
>LEU3_AGRT5 (P24404) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 370 Score = 41.6 bits (96), Expect = 0.002 Identities = 42/135 (31%), Positives = 60/135 (44%), Gaps = 1/135 (0%) Frame = -2 Query: 628 NYDGDVQSDFLAQGFGSLGLMTSV-LMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNS 452 N GD+ SD A GSLG++ S L PD KT + +A + V H G++ N Sbjct: 246 NLFGDMLSDVAAMLTGSLGMLPSASLGAPDAKTGKRKAMYEPV--HGSAPDIAGKSIANP 303 Query: 451 IASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTRS 272 IA I ++ L + + D A KLE A ++ G T D ++ G +V Sbjct: 304 IAMIASFAMCLRYSFNMVDE------ATKLEAAIANVLDKGIRTAD--IMADGCRQV--- 352 Query: 271 DYLNTEEFIDAVAAE 227 T + DAV AE Sbjct: 353 ---GTSDMGDAVLAE 364
>LEU3_PELUB (Q4FP17) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 368 Score = 40.4 bits (93), Expect = 0.005 Identities = 36/119 (30%), Positives = 51/119 (42%) Frame = -2 Query: 628 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 449 N GD+ SD + GSLGL+ S + K E A + + H G+ N I Sbjct: 249 NLFGDMLSDQASMLTGSLGLLPSASLGAKNKDGEMRAMYEPI--HGSAPDIAGKEIANPI 306 Query: 448 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTRS 272 ASI ++ L + LD A LE+A + G TKD +L G +V+ S Sbjct: 307 ASILSFAMALRYSLDLDSE------ADALEKAVQDVLNDGLRTKD--ILSQGKKEVSTS 357
>IDH3A_RAT (Q99NA5) Isocitrate dehydrogenase [NAD] subunit alpha,| mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 366 Score = 40.4 bits (93), Expect = 0.005 Identities = 42/127 (33%), Positives = 57/127 (44%), Gaps = 1/127 (0%) Frame = -2 Query: 628 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 449 N GD+ SD A G LG+ S + +G I E+ HGT G+ N Sbjct: 253 NLYGDILSDLCAGLIGGLGVTQSGNIGANGVAI-FESVHGTAP------DIAGKDMANPT 305 Query: 448 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGK-MTKDLALLVHGSSKVTRS 272 A + + L H L + A K+E AC T++ GK +TKDL G+SK S Sbjct: 306 ALLLSAVMMLRHMG-------LFDHAAKIEAACFATIKDGKSLTKDLG----GNSKC--S 352 Query: 271 DYLNTEE 251 D+ TEE Sbjct: 353 DF--TEE 357
>IDH3A_BOVIN (P41563) Isocitrate dehydrogenase [NAD] subunit alpha,| mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) (Isocitrate dehydrogenase subunits 3/4) Length = 366 Score = 40.4 bits (93), Expect = 0.005 Identities = 42/127 (33%), Positives = 57/127 (44%), Gaps = 1/127 (0%) Frame = -2 Query: 628 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 449 N GD+ SD A G LG+ S + +G I E+ HGT G+ N Sbjct: 253 NLYGDILSDLCAGLIGGLGVTPSGNIGANGVAI-FESVHGTAP------DIAGKDMANPT 305 Query: 448 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGK-MTKDLALLVHGSSKVTRS 272 A + + L H L + A K+E AC T++ GK +TKDL G+SK S Sbjct: 306 ALLLSAVMMLRHMG-------LFDHAAKIETACFATIKDGKSLTKDLG----GNSKC--S 352 Query: 271 DYLNTEE 251 D+ TEE Sbjct: 353 DF--TEE 357
>LEU3_RHIME (Q92KY8) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 370 Score = 40.4 bits (93), Expect = 0.005 Identities = 42/135 (31%), Positives = 60/135 (44%), Gaps = 1/135 (0%) Frame = -2 Query: 628 NYDGDVQSDFLAQGFGSLGLMTSV-LMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNS 452 N GD+ SD A GSLG++ S L PD KT + +A + V H G N Sbjct: 246 NLFGDMLSDVAAMLTGSLGMLPSASLGAPDAKTGKRKALYEPV--HGSAPDIAGTGVANP 303 Query: 451 IASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTRS 272 IA I ++ L + + L++ A LE+A ++ G T D ++ G KV Sbjct: 304 IAMIASFAMCLRY------SFNLVKEADDLEKAIANVLDQGIRTGD--IMAEGCRKV--- 352 Query: 271 DYLNTEEFIDAVAAE 227 T E DA+ AE Sbjct: 353 ---GTAEMGDAILAE 364
>IDH3A_MOUSE (Q9D6R2) Isocitrate dehydrogenase [NAD] subunit alpha,| mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 366 Score = 39.7 bits (91), Expect = 0.009 Identities = 34/107 (31%), Positives = 47/107 (43%), Gaps = 1/107 (0%) Frame = -2 Query: 628 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 449 N GD+ SD A G LG+ S + +G I E+ HGT G+ N Sbjct: 253 NLYGDILSDLCAGLIGGLGVTPSGNIGANGVAI-FESVHGTAP------DIAGKDMANPT 305 Query: 448 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGK-MTKDL 311 A + + L H L + A K+E AC T++ GK +TKDL Sbjct: 306 ALLLSAVMMLRHMG-------LFDHAAKIEAACFATIKDGKSLTKDL 345
>LEU3_BUCUE (Q9EVH5) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 364 Score = 38.1 bits (87), Expect = 0.026 Identities = 39/153 (25%), Positives = 64/153 (41%), Gaps = 1/153 (0%) Frame = -2 Query: 688 IDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAH 512 ID+ + +K + V C N GD+ SD A GS+G++ S + + E A Sbjct: 226 IDNAIMQIIKDPSQFDVILCSNLFGDIVSDECAAITGSIGMLPSASLNEKNFGL-YEPAG 284 Query: 511 GTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVES 332 G+ G+ N IA I + + + H L + A K++E+ V ++ Sbjct: 285 GSAP------DIAGKNIANPIAQILSVSMLVRH------GMNLKKIADKIDESVVSVLKQ 332 Query: 331 GKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 233 G T D++ H +YL T E D +A Sbjct: 333 GYRTADISNNSH--------NYLKTSEMGDIIA 357
>LEU3_NEIMB (Q9JZI9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 356 Score = 38.1 bits (87), Expect = 0.026 Identities = 33/111 (29%), Positives = 53/111 (47%) Frame = -2 Query: 643 VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGET 464 V A N GD+ SD + GS+G++ S + +GK + E +HG+ G+ Sbjct: 238 VIATGNIFGDILSDEASMLTGSIGMLPSASLDENGKGL-YEPSHGSAP------DIAGQN 290 Query: 463 STNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 311 N +A+I + L R L+D AR AQ++E A ++ G T D+ Sbjct: 291 KANPLATILSLAMLL--RYSLNDEAR----AQQVENAVQKVLQQGLRTSDI 335
>LEU3_RHILO (Q98E57) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 367 Score = 38.1 bits (87), Expect = 0.026 Identities = 33/107 (30%), Positives = 49/107 (45%), Gaps = 1/107 (0%) Frame = -2 Query: 628 NYDGDVQSDFLAQGFGSLGLMTSV-LMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNS 452 N GD+ SD A GS+G++ S L PD KT + +A + V H G+ N Sbjct: 246 NLFGDMLSDIAAMLTGSIGMLPSASLGAPDVKTKKRKALYEPV--HGSAPDIAGKGIANP 303 Query: 451 IASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 311 IA I ++ L + + D A +LE A ++ G TKD+ Sbjct: 304 IAMIASFAMCLRYSFGMVDE------ADRLEGAIAAVLDQGLRTKDI 344
>LEU3_BACME (P41019) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 367 Score = 38.1 bits (87), Expect = 0.026 Identities = 35/135 (25%), Positives = 59/135 (43%), Gaps = 1/135 (0%) Frame = -2 Query: 631 KNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNS 452 +N GD+ SD + GSLG++ S + DG ++ E HG+ G+ N Sbjct: 239 ENMFGDILSDEASMLTGSLGMLPSASLTADGPSL-YEPVHGSAP------DIAGQNKANP 291 Query: 451 I-ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTR 275 I A+I + L H L+ A + +E+A + +G T DLA Sbjct: 292 IAAAILSAAMLLRHSFGLEKEAAV------IEQAVESVLHAGHRTADLA---------DG 336 Query: 274 SDYLNTEEFIDAVAA 230 + YL T++ ++ + A Sbjct: 337 NHYLGTDKMVEVITA 351
>LEU3_WOLSU (Q7M886) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 358 Score = 37.7 bits (86), Expect = 0.033 Identities = 34/124 (27%), Positives = 58/124 (46%) Frame = -2 Query: 628 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 449 N GD+ SD + GS+GL+ S + GK E HG+ G+ N I Sbjct: 240 NLFGDILSDEASMLSGSIGLLPSASI--GGKAALYEPIHGSAP------DIAGQGIANPI 291 Query: 448 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTRSD 269 A+I + + L H + +E A +++A V T++ G TKD+A G+ ++ +D Sbjct: 292 ATIASASMMLRH------SLGEVEAADAIDKAIVKTLKEGYRTKDIA--AFGAKEICTTD 343 Query: 268 YLNT 257 + + Sbjct: 344 EMGS 347
>LEU3_SHEON (Q8E9N3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 364 Score = 37.4 bits (85), Expect = 0.044 Identities = 34/111 (30%), Positives = 48/111 (43%) Frame = -2 Query: 643 VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGET 464 V C N GD+ SD +A GS+GL++S M G + E A G+ G+ Sbjct: 240 VMLCSNLFGDILSDEIAMLTGSMGLLSSASMNSTGFGL-FEPAGGSAP------DIAGKG 292 Query: 463 STNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 311 N IA I + L H K + E A +E A + SG +T +L Sbjct: 293 IANPIAQILSAALMLRHSLKQE------EAASAIERAVTKALNSGYLTGEL 337
>LEU3_PHOPR (Q6LV25) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 37.4 bits (85), Expect = 0.044 Identities = 42/154 (27%), Positives = 67/154 (43%), Gaps = 1/154 (0%) Frame = -2 Query: 688 IDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAH 512 ID+ +K + V C N GD+ SD A GS+G++ S + + K E A Sbjct: 226 IDNATMQLIKDPSQFDVMLCSNIFGDIISDECAMITGSMGMLPSASLNQE-KFGMYEPAG 284 Query: 511 GTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVES 332 G+ G+ N +A I + L R LD+ + A+ +E+A +E+ Sbjct: 285 GSAP------DIAGKNIANPVAQIL--SAALMLRYSLDEE----KAARAIEQAVSQALEA 332 Query: 331 GKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVAA 230 G++T DLA + L+T E D +AA Sbjct: 333 GELTADLA---------GKGAALSTSEMGDKIAA 357
>LEU3_NEIMA (Q9JU79) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 356 Score = 37.0 bits (84), Expect = 0.057 Identities = 32/111 (28%), Positives = 53/111 (47%) Frame = -2 Query: 643 VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGET 464 V A N GD+ SD + GS+G++ S + +GK + E +HG+ G+ Sbjct: 238 VIATGNIFGDILSDEASMLTGSIGMLPSASLDENGKGL-YEPSHGSAP------DIAGQN 290 Query: 463 STNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 311 N +A++ + L R L+D AR AQ++E A ++ G T D+ Sbjct: 291 KANPLATVLSLAMLL--RYSLNDEAR----AQQVENAVQKVLQQGLRTGDI 335
>LEU3_BUCUA (Q9EVG6) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 37.0 bits (84), Expect = 0.057 Identities = 37/154 (24%), Positives = 66/154 (42%), Gaps = 1/154 (0%) Frame = -2 Query: 688 IDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAH 512 ID+ +K + V C N GD+ SD A GS+G++ S + + K E A Sbjct: 226 IDNATMQIIKDPNQFDVLLCSNLFGDIISDECAMITGSIGMLPSASL-NEKKFGLYEPAG 284 Query: 511 GTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVES 332 G+ G+ N IA I + + + + + L + A K++++ + ++ Sbjct: 285 GSAP------DIEGKNIANPIAQILSLSMLVRY------SMNLKKIADKIDQSVISVLKK 332 Query: 331 GKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVAA 230 G T D++ +DYL T E D +A+ Sbjct: 333 GYRTADIS---------NNNDYLKTNEMGDVIAS 357
>LEU3_RHOPA (Q6ND82) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 370 Score = 36.6 bits (83), Expect = 0.074 Identities = 33/107 (30%), Positives = 50/107 (46%), Gaps = 1/107 (0%) Frame = -2 Query: 628 NYDGDVQSDFLAQGFGSLGLMTSVLMCP-DGKTIEAEAAHGTVTRHFRVHQKGGETSTNS 452 N GD+ SD A GSLG++ S + D KT + ++ + V H G+ N Sbjct: 246 NLFGDMLSDIAAMLTGSLGMLPSASLGEVDAKTGKRKSMYEPV--HGSAPDIAGKGMANP 303 Query: 451 IASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 311 +A + ++ G+A R LD A A KL+EA + G T D+ Sbjct: 304 VAMLASF--GMALRYSLDMGA----LADKLDEAIAAVLAKGLRTADI 344
>LEU3_NEIG1 (Q5F8T6) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 356 Score = 36.2 bits (82), Expect = 0.097 Identities = 32/111 (28%), Positives = 53/111 (47%) Frame = -2 Query: 643 VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGET 464 V A N GD+ SD + GS+G++ S + +GK + E +HG+ G+ Sbjct: 238 VIATGNIFGDILSDEASMLTGSIGMLPSASLDENGKGL-YEPSHGSAP------DIAGQN 290 Query: 463 STNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 311 N +A+I + L R L+D AR AQ++E + ++ G T D+ Sbjct: 291 KANPLATILSLAMLL--RYSLNDEAR----AQQVENSVQKVLQQGLRTGDI 335
>LEU3_BRUSU (Q8FVF3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 370 Score = 36.2 bits (82), Expect = 0.097 Identities = 41/135 (30%), Positives = 60/135 (44%), Gaps = 1/135 (0%) Frame = -2 Query: 628 NYDGDVQSDFLAQGFGSLGLMTSV-LMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNS 452 N GD+ SD A GSLG++ S L D KT + +A + V H G+ N Sbjct: 246 NLFGDLLSDVAAMLTGSLGMLPSASLGAADSKTGKRKALYEPV--HGSAPDIAGKGIANP 303 Query: 451 IASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTRS 272 IA I + L + + L+ A +LE A G ++ G T D + G++KV Sbjct: 304 IAMIASLAMCLRY------SFGLVAEADRLEAAIAGVLDDGIRTAD--IWSEGNTKV--- 352 Query: 271 DYLNTEEFIDAVAAE 227 T E DA+ A+ Sbjct: 353 ---GTTEMGDAILAK 364
>LEU3_BRUME (Q8YCX4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 370 Score = 36.2 bits (82), Expect = 0.097 Identities = 41/135 (30%), Positives = 60/135 (44%), Gaps = 1/135 (0%) Frame = -2 Query: 628 NYDGDVQSDFLAQGFGSLGLMTSV-LMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNS 452 N GD+ SD A GSLG++ S L D KT + +A + V H G+ N Sbjct: 246 NLFGDLLSDVAAMLTGSLGMLPSASLGAADSKTGKRKALYEPV--HGSAPDIAGKGIANP 303 Query: 451 IASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTRS 272 IA I + L + + L+ A +LE A G ++ G T D + G++KV Sbjct: 304 IAMIASLAMCLRY------SFGLVAEADRLEAAIAGVLDDGIRTAD--IWSEGNTKV--- 352 Query: 271 DYLNTEEFIDAVAAE 227 T E DA+ A+ Sbjct: 353 ---GTTEMGDAILAK 364
>LEU3_DESPS (Q6ANR1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 357 Score = 35.8 bits (81), Expect = 0.13 Identities = 40/138 (28%), Positives = 56/138 (40%) Frame = -2 Query: 643 VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGET 464 V C N GD+ SD A GS+GL+ S + + + E A G+ G+ Sbjct: 239 VMLCGNMFGDIISDEAAMLTGSMGLLASASLNTENFGL-FEPAGGSAP------DIAGQG 291 Query: 463 STNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSK 284 N IA I + L + E A +E A T++ G T D+A Sbjct: 292 IANPIAEILSAAMMLRYSLGYG------EAADAIEAAVEKTLDRGICTADIA-------- 337 Query: 283 VTRSDYLNTEEFIDAVAA 230 V RS +NT E DA+ A Sbjct: 338 VDRSQAVNTAEMGDAIVA 355
>LEU3_BUCUO (Q9EVI1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 364 Score = 35.4 bits (80), Expect = 0.17 Identities = 37/153 (24%), Positives = 66/153 (43%), Gaps = 1/153 (0%) Frame = -2 Query: 688 IDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAH 512 ID+ + +K+ + V C N GD+ SD A GS+G++ S + + K E A Sbjct: 227 IDNAIMQIIKNPNQFDVLLCPNLFGDIISDECAIITGSIGMLPSASL-NEKKFGLYEPAG 285 Query: 511 GTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVES 332 G+ G+ N IA I + + + + L D A K++++ + ++ Sbjct: 286 GSAP------DIAGKNIANPIAQILSLSMLVRYGMNLKD------IADKIDKSVLSVLKK 333 Query: 331 GKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 233 G T D++ ++YL T E D +A Sbjct: 334 GYRTADIS---------NNNNYLKTNEMGDVIA 357
>LEU3_SHIDS (Q32K21) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 35.4 bits (80), Expect = 0.17 Identities = 42/153 (27%), Positives = 63/153 (41%), Gaps = 1/153 (0%) Frame = -2 Query: 688 IDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAH 512 ID+ +K + V C N GD+ SD A GS+G++ S + G + E A Sbjct: 226 IDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YEPAG 284 Query: 511 GTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVES 332 G+ G+ N IA I + L + DD A +E A +E Sbjct: 285 GSAP------DIAGKNIANPIAQILSLALLLRYSLDADD------AASAIERAINRALEE 332 Query: 331 GKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 233 G T+DLA G++ V +T+E D +A Sbjct: 333 GIRTRDLA---RGAAAV------STDEMGDIIA 356
>LEU3_LEPIN (P24015) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 358 Score = 35.4 bits (80), Expect = 0.17 Identities = 29/109 (26%), Positives = 50/109 (45%) Frame = -2 Query: 634 CKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 455 C+N GD+ SD + GS+G++ S + G + E + G+ G+ N Sbjct: 243 CENMFGDILSDEASIITGSIGMLPSASLSESGFGLY-EPSGGSAP------DIAGKGVAN 295 Query: 454 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLA 308 IA + + L + +++ A K+E A T+ SGK T+D+A Sbjct: 296 PIAQVLSAALMLRYSFSMEEEAN------KIETAVRKTIASGKRTRDIA 338
>LEU3_LEPIC (Q72RH7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 358 Score = 35.4 bits (80), Expect = 0.17 Identities = 29/109 (26%), Positives = 50/109 (45%) Frame = -2 Query: 634 CKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 455 C+N GD+ SD + GS+G++ S + G + E + G+ G+ N Sbjct: 243 CENMFGDILSDEASIITGSIGMLPSASLSESGFGLY-EPSGGSAP------DIAGKGVAN 295 Query: 454 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLA 308 IA + + L + +++ A K+E A T+ SGK T+D+A Sbjct: 296 PIAQVLSAALMLRYSFSMEEEAN------KIETAVRKTIASGKRTRDIA 338
>LEU3_HAEIN (P43860) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 358 Score = 35.4 bits (80), Expect = 0.17 Identities = 37/128 (28%), Positives = 54/128 (42%), Gaps = 1/128 (0%) Frame = -2 Query: 688 IDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAH 512 ID+ +KS + V C N GD+ SD A GS+G++ S + +G + E A Sbjct: 225 IDNATMQLIKSPESFDVLLCSNIFGDIISDEAAMITGSMGMLPSASLNEEGFGL-YEPAG 283 Query: 511 GTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVES 332 G+ G+ N IA I + L + L+ E A +E A + S Sbjct: 284 GSAP------DIAGKGIANPIAQILSAAMMLRYSFNLN------EAADAIESAVQKVLAS 331 Query: 331 GKMTKDLA 308 G T DLA Sbjct: 332 GHRTADLA 339
>LEU3_SALTY (P37412) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 35.0 bits (79), Expect = 0.22 Identities = 44/153 (28%), Positives = 65/153 (42%), Gaps = 1/153 (0%) Frame = -2 Query: 688 IDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAH 512 ID+ +K + V C N GD+ SD A GS+G++ S + G + E A Sbjct: 226 IDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YEPAG 284 Query: 511 GTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVES 332 G+ G+ N IA I + L R LD N + A +E+A +E Sbjct: 285 GSAP------DIAGKNIANPIAQIL--SLALLLRYSLDAN----DAATAIEQAINRALEE 332 Query: 331 GKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 233 G T DLA G++ V +T+E D +A Sbjct: 333 GVRTGDLA---RGAAAV------STDEMGDIIA 356
>LEU3_SALPA (Q5PDG2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 35.0 bits (79), Expect = 0.22 Identities = 44/153 (28%), Positives = 65/153 (42%), Gaps = 1/153 (0%) Frame = -2 Query: 688 IDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAH 512 ID+ +K + V C N GD+ SD A GS+G++ S + G + E A Sbjct: 226 IDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YEPAG 284 Query: 511 GTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVES 332 G+ G+ N IA I + L R LD N + A +E+A +E Sbjct: 285 GSAP------DIAGKNIANPIAQIL--SLALLLRYSLDAN----DAATAIEQAINRALEE 332 Query: 331 GKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 233 G T DLA G++ V +T+E D +A Sbjct: 333 GVRTGDLA---RGAAAV------STDEMGDIIA 356
>LEU3_SALCH (Q57TE7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 35.0 bits (79), Expect = 0.22 Identities = 44/153 (28%), Positives = 65/153 (42%), Gaps = 1/153 (0%) Frame = -2 Query: 688 IDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAH 512 ID+ +K + V C N GD+ SD A GS+G++ S + G + E A Sbjct: 226 IDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YEPAG 284 Query: 511 GTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVES 332 G+ G+ N IA I + L R LD N + A +E+A +E Sbjct: 285 GSAP------DIAGKNIANPIAQIL--SLALLLRYSLDAN----DAATAIEQAINRALEE 332 Query: 331 GKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 233 G T DLA G++ V +T+E D +A Sbjct: 333 GVRTGDLA---RGAAAV------STDEMGDIIA 356
>LEU3_PASMU (Q9CJN6) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 359 Score = 35.0 bits (79), Expect = 0.22 Identities = 39/137 (28%), Positives = 55/137 (40%) Frame = -2 Query: 643 VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGET 464 V C N GD+ SD A GS+G++ S + G + E A G+ G+ Sbjct: 241 VLLCSNIFGDIISDECAMITGSMGMLPSASLNEKGFGL-YEPAGGSAP------DIAGKG 293 Query: 463 STNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSK 284 N IA I + L H L+D A +E A K + G T DLA Sbjct: 294 IANPIAQILSAAMMLRHSFNLNDAATAIENAVK------NVLAEGHRTADLA-------- 339 Query: 283 VTRSDYLNTEEFIDAVA 233 S L+T++ D +A Sbjct: 340 -DESQPLSTKQMGDLIA 355
>LEU3_BACSU (P05645) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 365 Score = 34.7 bits (78), Expect = 0.28 Identities = 39/135 (28%), Positives = 59/135 (43%) Frame = -2 Query: 631 KNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNS 452 +N GD+ SD + GSLG++ S + G + E HG+ G+ N Sbjct: 243 ENMFGDILSDEASMLTGSLGMLPSASLSSSGLHL-FEPVHGSAP------DIAGKGMANP 295 Query: 451 IASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTRS 272 A+I L+ L + L E A+ +E+A + SGK T+DLA S+ S Sbjct: 296 FAAI------LSAAMLLRTSFGLEEEAKAVEDAVNKVLASGKRTRDLA-----RSEEFSS 344 Query: 271 DYLNTEEFIDAVAAE 227 TEE A+ +E Sbjct: 345 TQAITEEVKAAIMSE 359
>LEU3_ZYMMO (Q5NPQ9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 349 Score = 34.7 bits (78), Expect = 0.28 Identities = 29/106 (27%), Positives = 47/106 (44%) Frame = -2 Query: 628 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 449 N GD+ SD + GS+GL+ S + +GK + E HG+ G N + Sbjct: 239 NLFGDILSDLASACVGSIGLLPSASLNSEGKGL-YEPIHGSAP------DIAGLGKANPL 291 Query: 448 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 311 A+I + L + K + + A ++E+A +E G T DL Sbjct: 292 ATILSGAMMLRYSLKREAD------ADRIEKAVSTALEKGARTADL 331
>LEU3_BACLD (Q65GI9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 370 Score = 34.7 bits (78), Expect = 0.28 Identities = 32/108 (29%), Positives = 48/108 (44%) Frame = -2 Query: 631 KNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNS 452 +N GD+ SD + GSLG++ S + G + E HG+ G+ N Sbjct: 243 ENMFGDILSDEASMLTGSLGMLPSASLSSSGLHLY-EPVHGSAP------DIAGQNIANP 295 Query: 451 IASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLA 308 +A+I L+ L + L AQ +E A + +GK TKDLA Sbjct: 296 LAAI------LSAAMMLRTSFGLEAEAQAVEHAVDQVLRAGKRTKDLA 337
>LEU3_ARCFU (O29627) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 326 Score = 34.7 bits (78), Expect = 0.28 Identities = 33/106 (31%), Positives = 44/106 (41%) Frame = -2 Query: 628 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 449 N GD+ SD A G LGL S + +T E HG F + KG T I Sbjct: 218 NMFGDIVSDLAAGLVGGLGLAPSANV--GERTAIFEPVHGAA---FDIAGKGIANPTAMI 272 Query: 448 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 311 + R + +E A+K+EEA T++ GK T DL Sbjct: 273 LTACMMLRHFGY----------VEEAKKVEEAVEKTIKEGKKTPDL 308
>LEU3_GLOVI (Q7NFH4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 34.7 bits (78), Expect = 0.28 Identities = 30/108 (27%), Positives = 46/108 (42%) Frame = -2 Query: 631 KNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNS 452 +N GD+ SD A GS+G++ S + G + E HG+ G+ N Sbjct: 245 ENMFGDILSDEAAMLTGSIGMLPSASLGSGGPGL-YEPVHGSAP------DIAGQDKANP 297 Query: 451 IASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLA 308 +A + + L H + R E AQ +E A +E G T D+A Sbjct: 298 LAQVLSGAMLLRH------SLRQPEAAQAVERAVQTVLEQGYRTGDIA 339
>LEU3_COLP3 (Q47WG3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 34.7 bits (78), Expect = 0.28 Identities = 34/111 (30%), Positives = 49/111 (44%) Frame = -2 Query: 643 VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGET 464 V C N GD+ SD A GS+GL+ S + DG + E A G+ G Sbjct: 239 VMLCPNLFGDILSDICAMITGSMGLLPSASLNSDGFGM-YEPAGGSAP------DIAGLG 291 Query: 463 STNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 311 N IA I + L R L+ A A+ +E+A +++G +T DL Sbjct: 292 VANPIAQIL--SAALMLRYSLNQGAA----AKAIEDAVSNALDNGVLTADL 336
>LEU3_METTH (O27441) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 329 Score = 34.7 bits (78), Expect = 0.28 Identities = 34/106 (32%), Positives = 43/106 (40%) Frame = -2 Query: 628 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 449 N GD+ SD A G LGL S + K E HG+ Q G+ N Sbjct: 220 NLFGDILSDEAAGLIGGLGLAPSANI--GEKNALFEPVHGSAP------QIAGKNIANPT 271 Query: 448 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 311 A I T L H K + AQK+E+A T+ G +T DL Sbjct: 272 AMILTTTLMLKHLNKKQE-------AQKIEKALQKTLAEGLVTPDL 310
>IDH3A_DROME (Q9VWH4) Probable isocitrate dehydrogenase [NAD] subunit alpha,| mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 377 Score = 34.3 bits (77), Expect = 0.37 Identities = 37/128 (28%), Positives = 53/128 (41%), Gaps = 2/128 (1%) Frame = -2 Query: 688 IDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAH 512 +D + +++ G Y V N GD+ SD A G LGL S M +G E+ H Sbjct: 248 LDTVCLNMVQNPGKYDVLVMPNLYGDILSDMCAGLVGGLGLTPSGNMGLNGALF--ESVH 305 Query: 511 GTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVES 332 GT G+ N A + + L H L +A K+E A T++ Sbjct: 306 GTAP------DIAGKDLANPTALLLSAVMMLRH-------MELNTYADKIERAAFETIKE 352 Query: 331 GK-MTKDL 311 GK +T DL Sbjct: 353 GKYLTGDL 360
>LEU3_YERPE (Q8ZIG9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 34.3 bits (77), Expect = 0.37 Identities = 37/128 (28%), Positives = 51/128 (39%), Gaps = 1/128 (0%) Frame = -2 Query: 688 IDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAH 512 ID+ +K + V C N GD+ SD A GS+G++ S + G + E A Sbjct: 226 IDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YEPAG 284 Query: 511 GTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVES 332 G+ G+ N IA I + T L DD A +E A +E Sbjct: 285 GSAP------DIAGKNIANPIAQILSLTLLLRFSLGKDD------AADAIERAINQALEQ 332 Query: 331 GKMTKDLA 308 G T DLA Sbjct: 333 GYRTADLA 340
>LEU3_VIBPA (Q87SS8) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 34.3 bits (77), Expect = 0.37 Identities = 36/128 (28%), Positives = 55/128 (42%), Gaps = 1/128 (0%) Frame = -2 Query: 688 IDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAH 512 ID+ +K + V C N GD+ SD A GS+G++ S + + K E A Sbjct: 227 IDNATMQLIKDPAQFDVMLCSNIFGDIISDECAMITGSMGMLPSASL-NESKFGLYEPAG 285 Query: 511 GTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVES 332 G+ G+ N +A I + L R L + A AQ +E A + + Sbjct: 286 GSAP------DIAGKNIANPVAQIL--SAALMLRYSLGEEAA----AQDIESAVSKALSA 333 Query: 331 GKMTKDLA 308 G++T DLA Sbjct: 334 GELTADLA 341
>LEU3_NITWN (Q3SNU3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 370 Score = 34.3 bits (77), Expect = 0.37 Identities = 34/107 (31%), Positives = 47/107 (43%), Gaps = 1/107 (0%) Frame = -2 Query: 628 NYDGDVQSDFLAQGFGSLGLMTSV-LMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNS 452 N GD+ SD A GSLG++ S L D KT + A + V H G+ N Sbjct: 246 NLFGDMLSDIAAMLTGSLGMLPSASLGDTDPKTEKRRALYEPV--HGSAPDIAGQGLANP 303 Query: 451 IASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 311 IA + ++ G+A R D + A KL+ A + G T DL Sbjct: 304 IAMLASF--GMALRYSFDRG----DLADKLDAAIAAVLAKGLRTADL 344
>LEU3_ERWCT (Q6D0G7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 34.3 bits (77), Expect = 0.37 Identities = 40/153 (26%), Positives = 61/153 (39%), Gaps = 1/153 (0%) Frame = -2 Query: 688 IDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAH 512 ID+ +K + V C N GD+ SD A GS+G++ S + G + E A Sbjct: 226 IDNATMQLIKDPSQFDVMLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YEPAG 284 Query: 511 GTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVES 332 G+ G+ N IA I + L + DD A+ +E+A + Sbjct: 285 GSAP------DIAGKDIANPIAQILSLALLLRYSLGADD------AAEAIEKAVNTALAE 332 Query: 331 GKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 233 G T DLA + S+ + T E D +A Sbjct: 333 GYRTADLA---------SASNAIGTSEMGDVIA 356
>LEU3_BUCUS (Q9EVI4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 34.3 bits (77), Expect = 0.37 Identities = 36/154 (23%), Positives = 65/154 (42%), Gaps = 1/154 (0%) Frame = -2 Query: 688 IDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAH 512 ID+ +K+ + + C N GD+ SD A GS+G++ S + + K E A Sbjct: 226 IDNATMQIIKNPNQFDILLCSNLFGDIISDECAMITGSIGMLPSASL-NEKKFGLYEPAG 284 Query: 511 GTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVES 332 G+ G+ N IA I + + + + + L A K++++ + ++ Sbjct: 285 GSAP------DIEGKNIANPIAQILSVSMLVRY------SMNLKTIADKIDQSVISVLKK 332 Query: 331 GKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVAA 230 G T D++ S YL T E D +A+ Sbjct: 333 GYRTADIS---------NNSHYLKTNEMGDVIAS 357
>LEU3_SULSO (Q9UXB2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 336 Score = 33.9 bits (76), Expect = 0.48 Identities = 37/117 (31%), Positives = 58/117 (49%), Gaps = 1/117 (0%) Frame = -2 Query: 628 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 449 N GD+ SD +Q GSLGL S + D K++ E HG F + KG N Sbjct: 221 NVYGDILSDEASQIAGSLGLAPSANI-GDRKSM-FEPVHGAA---FDIAGKG---IANPT 272 Query: 448 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESG-KMTKDLALLVHGSSKV 281 A + + + L+ +L + + ++ LE A + T +SG K+T+D V GS+K+ Sbjct: 273 AFLLSVSMMLSRMYELSKENKYILASKSLENAIIETYKSGNKLTED----VGGSAKL 325
>LEU3_VIBVY (Q7MP78) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 33.9 bits (76), Expect = 0.48 Identities = 36/128 (28%), Positives = 55/128 (42%), Gaps = 1/128 (0%) Frame = -2 Query: 688 IDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAH 512 ID+ +K + V C N GD+ SD A GS+G++ S + + K E A Sbjct: 227 IDNATMQLIKDPAQFDVMLCSNIFGDIISDECAMITGSMGMLPSASL-NESKFGLYEPAG 285 Query: 511 GTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVES 332 G+ G+ N +A I + L R L + A AQ +E A + + Sbjct: 286 GSAP------DIAGKNIANPVAQIL--SAALMLRYSLGEEAA----AQDIENAVSQALAA 333 Query: 331 GKMTKDLA 308 G++T DLA Sbjct: 334 GELTADLA 341
>LEU3_VIBVU (Q8DEE0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 33.9 bits (76), Expect = 0.48 Identities = 36/128 (28%), Positives = 55/128 (42%), Gaps = 1/128 (0%) Frame = -2 Query: 688 IDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAH 512 ID+ +K + V C N GD+ SD A GS+G++ S + + K E A Sbjct: 227 IDNATMQLIKDPAQFDVMLCSNIFGDIISDECAMITGSMGMLPSASL-NESKFGLYEPAG 285 Query: 511 GTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVES 332 G+ G+ N +A I + L R L + A AQ +E A + + Sbjct: 286 GSAP------DIAGKNIANPVAQIL--SAALMLRYSLGEEAA----AQDIENAVSQALAA 333 Query: 331 GKMTKDLA 308 G++T DLA Sbjct: 334 GELTADLA 341
>LEU3_VIBCH (Q9KP82) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 33.9 bits (76), Expect = 0.48 Identities = 36/128 (28%), Positives = 55/128 (42%), Gaps = 1/128 (0%) Frame = -2 Query: 688 IDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAH 512 ID+ +K + V C N GD+ SD A GS+G++ S M + K E A Sbjct: 227 IDNATMQLIKDPAQFDVMLCSNIFGDILSDECAMITGSMGMLPSASM-NESKFGLYEPAG 285 Query: 511 GTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVES 332 G+ G+ N +A I + L R L + A A+ +E A + + Sbjct: 286 GSAP------DIAGKNIANPVAQIL--SAALMLRYSLGEEAA----ARDIENAVSQALAA 333 Query: 331 GKMTKDLA 308 G++T DLA Sbjct: 334 GELTADLA 341
>LEU3_BUCDN (O85071) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 33.9 bits (76), Expect = 0.48 Identities = 36/153 (23%), Positives = 63/153 (41%), Gaps = 1/153 (0%) Frame = -2 Query: 688 IDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAH 512 ID++ +K + V C N GD+ SD A GS+G++ S + + E A Sbjct: 226 IDNVCMQIIKDPNQFDVLLCSNLFGDIISDECAMITGSIGMLPSASLNEKNFGL-YEPAG 284 Query: 511 GTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVES 332 G+ G+ N IA I + + + + L+ + A K++ A + ++ Sbjct: 285 GSAP------DIQGKNIANPIAQILSLSMLIRYSMNLN------KIANKIDNAVINVLKK 332 Query: 331 GKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 233 G T D++ +YL T E D +A Sbjct: 333 GYKTMDIS---------KDQNYLKTNEMGDVIA 356
>LEU3_SHIFL (Q83SP1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 33.9 bits (76), Expect = 0.48 Identities = 42/153 (27%), Positives = 62/153 (40%), Gaps = 1/153 (0%) Frame = -2 Query: 688 IDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAH 512 ID+ +K + V C N GD+ SD A GS+G++ S + G + E A Sbjct: 225 IDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YEPAG 283 Query: 511 GTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVES 332 G+ G+ N IA I + L + DD A +E A +E Sbjct: 284 GSAP------DIAGKNIANPIAQILSLALLLRYSLDADD------AASAIERAINRALEE 331 Query: 331 GKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 233 G T DLA G++ V +T+E D +A Sbjct: 332 GIRTGDLA---RGAAAV------STDEMGDIIA 355
>LEU3_ECOL6 (Q8FL76) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 33.9 bits (76), Expect = 0.48 Identities = 42/153 (27%), Positives = 62/153 (40%), Gaps = 1/153 (0%) Frame = -2 Query: 688 IDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAH 512 ID+ +K + V C N GD+ SD A GS+G++ S + G + E A Sbjct: 225 IDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YEPAG 283 Query: 511 GTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVES 332 G+ G+ N IA I + L + DD A +E A +E Sbjct: 284 GSAP------DIAGKNIANPIAQILSLALLLRYSLDADD------AASAIERAINRALEE 331 Query: 331 GKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 233 G T DLA G++ V +T+E D +A Sbjct: 332 GIRTGDLA---RGAAAV------STDEMGDIIA 355
>LEU3_ECO57 (Q8X9Z9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 33.9 bits (76), Expect = 0.48 Identities = 42/153 (27%), Positives = 62/153 (40%), Gaps = 1/153 (0%) Frame = -2 Query: 688 IDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAH 512 ID+ +K + V C N GD+ SD A GS+G++ S + G + E A Sbjct: 225 IDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YEPAG 283 Query: 511 GTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVES 332 G+ G+ N IA I + L + DD A +E A +E Sbjct: 284 GSAP------DIAGKNIANPIAQILSLALLLRYSLDADD------AASAIERAINRALEE 331 Query: 331 GKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 233 G T DLA G++ V +T+E D +A Sbjct: 332 GIRTGDLA---RGAAAV------STDEMGDIIA 355
>LEU3_CAUCR (Q9ABN3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 350 Score = 33.9 bits (76), Expect = 0.48 Identities = 30/106 (28%), Positives = 44/106 (41%) Frame = -2 Query: 628 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 449 N GD+ SD A GSLG++ S + GK E HG+ G+ N + Sbjct: 240 NLFGDILSDAAAMLTGSLGMLPSAALGAPGKPGLYEPIHGSAP------DIAGKGLANPL 293 Query: 448 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 311 A+I ++ L K E A L A +++G T+DL Sbjct: 294 AAILSFEMALRWSLK------QTEAADALLAAVKAALDNGARTRDL 333
>LEU3_PHOLL (Q7N128) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 33.5 bits (75), Expect = 0.63 Identities = 40/145 (27%), Positives = 60/145 (41%), Gaps = 1/145 (0%) Frame = -2 Query: 688 IDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAH 512 ID+ +K + V C N GD+ SD A GS+G++ S + G + E A Sbjct: 226 IDNATMQLIKDPSQFDVMLCSNIFGDILSDECAMITGSMGMLPSASLNEKGFGL-YEPAG 284 Query: 511 GTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVES 332 G+ G+ N IA I + L R L N + A +E+A +E Sbjct: 285 GSAP------DIAGKGIANPIAQIL--SAALLLRYSLGHN----DAANAIEQAVNYALEQ 332 Query: 331 GKMTKDLALLVHGSSKVTRSDYLNT 257 G T DLA G+ K +D + + Sbjct: 333 GYRTTDLA----GNGKAISTDEMGS 353
>LEU3_BUCUH (Q9EVH8) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 33.5 bits (75), Expect = 0.63 Identities = 36/153 (23%), Positives = 67/153 (43%), Gaps = 1/153 (0%) Frame = -2 Query: 688 IDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAH 512 ID+ +K+ + V C N GD+ SD A GS+G++ S + E A Sbjct: 226 IDNATMQIIKNPNQFDVLLCSNLFGDIISDECAVITGSIGMLPSASFNEKNFGL-YEPAG 284 Query: 511 GTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVES 332 G+ G+ + N IA I + + + + KL+ + A K+++A ++++ Sbjct: 285 GSAP------DIAGKNTANPIAQILSLSMLVRYGMKLN------KIADKIDDAVALSLKA 332 Query: 331 GKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 233 G T D++ +++L T E D +A Sbjct: 333 GYRTADIS---------NDNNFLKTNEMGDVIA 356
>LEU3_STAAW (Q8NVJ0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 348 Score = 33.1 bits (74), Expect = 0.82 Identities = 29/111 (26%), Positives = 47/111 (42%) Frame = -2 Query: 643 VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGET 464 V C+N GD+ SD + GSLGL S DG + + +H + Sbjct: 232 VIVCENLFGDILSDEASVIPGSLGLSPSASFSNDGPRL-----------YEPIHGSAPDI 280 Query: 463 STNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 311 + ++A+ F LA L ++ + A +LE+ +E G+ T DL Sbjct: 281 AGKNVANPFGMILSLA--MCLRESLNQPDAADELEQHIYNMIEHGQTTADL 329
>LEU3_STAAS (Q6G7Q0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 348 Score = 33.1 bits (74), Expect = 0.82 Identities = 29/111 (26%), Positives = 47/111 (42%) Frame = -2 Query: 643 VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGET 464 V C+N GD+ SD + GSLGL S DG + + +H + Sbjct: 232 VIVCENLFGDILSDEASVIPGSLGLSPSASFSNDGPRL-----------YEPIHGSAPDI 280 Query: 463 STNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 311 + ++A+ F LA L ++ + A +LE+ +E G+ T DL Sbjct: 281 AGKNVANPFGMILSLA--MCLRESLNQPDAADELEQHIYNMIEHGQTTADL 329
>LEU3_STAAN (P65101) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 348 Score = 33.1 bits (74), Expect = 0.82 Identities = 29/111 (26%), Positives = 47/111 (42%) Frame = -2 Query: 643 VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGET 464 V C+N GD+ SD + GSLGL S DG + + +H + Sbjct: 232 VIVCENLFGDILSDEASVIPGSLGLSPSASFSNDGPRL-----------YEPIHGSAPDI 280 Query: 463 STNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 311 + ++A+ F LA L ++ + A +LE+ +E G+ T DL Sbjct: 281 AGKNVANPFGMILSLA--MCLRESLNQPDAADELEQHIYNMIEHGQTTADL 329
>LEU3_STAAM (P65100) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 348 Score = 33.1 bits (74), Expect = 0.82 Identities = 29/111 (26%), Positives = 47/111 (42%) Frame = -2 Query: 643 VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGET 464 V C+N GD+ SD + GSLGL S DG + + +H + Sbjct: 232 VIVCENLFGDILSDEASVIPGSLGLSPSASFSNDGPRL-----------YEPIHGSAPDI 280 Query: 463 STNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 311 + ++A+ F LA L ++ + A +LE+ +E G+ T DL Sbjct: 281 AGKNVANPFGMILSLA--MCLRESLNQPDAADELEQHIYNMIEHGQTTADL 329
>LEU3_STAAC (Q5HEE3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 348 Score = 33.1 bits (74), Expect = 0.82 Identities = 29/111 (26%), Positives = 47/111 (42%) Frame = -2 Query: 643 VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGET 464 V C+N GD+ SD + GSLGL S DG + + +H + Sbjct: 232 VIVCENLFGDILSDEASVIPGSLGLSPSASFSNDGPRL-----------YEPIHGSAPDI 280 Query: 463 STNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 311 + ++A+ F LA L ++ + A +LE+ +E G+ T DL Sbjct: 281 AGKNVANPFGMILSLA--MCLRESLNQPDAADELEQHIYSMIEHGQTTADL 329
>LEU3_STAHJ (Q4L7U1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 346 Score = 33.1 bits (74), Expect = 0.82 Identities = 32/124 (25%), Positives = 52/124 (41%) Frame = -2 Query: 631 KNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNS 452 +N GD+ SD + GSLGL S +G + + +H + + + Sbjct: 236 ENLFGDILSDEASTIPGSLGLSPSASFSLEGPRL-----------YEPIHGSAPDIANQN 284 Query: 451 IASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTRS 272 +A+ F LA L ++ + A +LE+A ++ GK TKDL + T S Sbjct: 285 LANPFGMILSLA--MCLRESFNFEDAASELEQAVYQLIKDGKTTKDL------NGHYTTS 336 Query: 271 DYLN 260 D N Sbjct: 337 DIFN 340
>LEU3_VIBF1 (Q5E857) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 33.1 bits (74), Expect = 0.82 Identities = 35/128 (27%), Positives = 54/128 (42%), Gaps = 1/128 (0%) Frame = -2 Query: 688 IDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAH 512 ID+ +K + V C N GD+ SD A GS+G++ S + + E A Sbjct: 227 IDNATMQLIKDPSQFDVMLCSNIFGDIISDECAMITGSMGMLPSASLNESNFGL-YEPAG 285 Query: 511 GTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVES 332 G+ G+ N +A I + L R L + E AQ +E A + + Sbjct: 286 GSAP------DIAGKNIANPVAQIL--SAALMLRYSLGEE----EAAQSIEAAVSKALSA 333 Query: 331 GKMTKDLA 308 G++T DLA Sbjct: 334 GELTADLA 341
>LEU3_BACHD (Q9K8E9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 33.1 bits (74), Expect = 0.82 Identities = 29/112 (25%), Positives = 49/112 (43%) Frame = -2 Query: 643 VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGET 464 V +N GD+ SD + GSLG++ S + DG + E HG+ G+ Sbjct: 238 VLVTENLFGDILSDEASMVTGSLGMLPSASLTSDGPGL-YEPIHGSAP------DIAGKG 290 Query: 463 STNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLA 308 N +A+I + L + L + A+ +E+A ++ G T D+A Sbjct: 291 VANPLATIASCAMMLKYSFGLHEEAK------TIEDAIEAVLKQGYRTADIA 336
>LEU3_SYNY3 (P73960) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 33.1 bits (74), Expect = 0.82 Identities = 29/106 (27%), Positives = 46/106 (43%) Frame = -2 Query: 628 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 449 N GD+ SD A GS+G++ S + DG + E HG+ G+ N + Sbjct: 246 NLFGDILSDIAAMLTGSIGMLPSASLGSDGPGL-FEPVHGSAP------DIAGQDKANPL 298 Query: 448 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 311 A + + + R LD + A +LE+A +E G T D+ Sbjct: 299 AQVL--SAAMMLRYGLDQP----QAADRLEDAVKKVLEQGYRTGDI 338
>LEU3_BUCUM (Q9EVG9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 365 Score = 32.7 bits (73), Expect = 1.1 Identities = 35/153 (22%), Positives = 64/153 (41%), Gaps = 1/153 (0%) Frame = -2 Query: 688 IDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAH 512 ID+ +K + + C N GD+ SD A GS+G++ S + + K E A Sbjct: 228 IDNATMQIIKDPNQFDILLCSNLFGDIVSDECAIITGSIGMLPSASL-NEKKFGLYEPAG 286 Query: 511 GTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVES 332 G+ G+ N IA I + + + + L + A K++++ + ++ Sbjct: 287 GSAP------DIEGKNIANPIAQILSVSMLVRY------GMNLKKIADKIDQSVISVLKK 334 Query: 331 GKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 233 G T D++ ++YL T E D +A Sbjct: 335 GYRTADIS---------NNNNYLKTNEMGDVIA 358
>LEU3_THIFE (Q56268) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 358 Score = 32.7 bits (73), Expect = 1.1 Identities = 28/107 (26%), Positives = 49/107 (45%) Frame = -2 Query: 628 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 449 N GD+ SD +Q GS+G++ S + +G+ + E HG+ G+ N + Sbjct: 242 NMFGDILSDEASQLTGSIGMLPSASL-GEGRAM-YEPIHGSAP------DIAGQDKANPL 293 Query: 448 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLA 308 A+I + L H + +AQ++E A ++ G T D+A Sbjct: 294 ATILSVAMMLRHSLNAE------PWAQRVEAAVQRVLDQGLRTADIA 334
>LEU3_SHISS (Q3Z5T7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 32.7 bits (73), Expect = 1.1 Identities = 42/153 (27%), Positives = 62/153 (40%), Gaps = 1/153 (0%) Frame = -2 Query: 688 IDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAH 512 ID+ +K + V C N GD+ SD A GS+G++ S + G + E A Sbjct: 226 IDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YEPAG 284 Query: 511 GTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVES 332 G+ G+ N IA I + L + DD A +E A +E Sbjct: 285 GSAP------DIAGKNIANPIAQILSLALLLRYSLDADD------AACAIERAINRALEE 332 Query: 331 GKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 233 G T DLA G++ V +T+E D +A Sbjct: 333 GIRTGDLA---RGAAAV------STDEMGDIIA 356
>LEU3_HAEI8 (Q4QLS3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 358 Score = 32.7 bits (73), Expect = 1.1 Identities = 36/128 (28%), Positives = 53/128 (41%), Gaps = 1/128 (0%) Frame = -2 Query: 688 IDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAH 512 ID+ +K+ + V C N GD+ SD A GS+G++ S + G + E A Sbjct: 225 IDNATMQLIKAPESFDVLLCSNIFGDIISDEAAMITGSMGMLPSASLNEAGFGL-YEPAG 283 Query: 511 GTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVES 332 G+ G+ N IA I + L + L+ E A +E A + S Sbjct: 284 GSAP------DIAGKGIANPIAQILSAAMMLRYSFNLN------EAADAIESAVQKVLAS 331 Query: 331 GKMTKDLA 308 G T DLA Sbjct: 332 GHRTADLA 339
>LEU3_BUCRP (P48572) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 32.7 bits (73), Expect = 1.1 Identities = 37/153 (24%), Positives = 63/153 (41%), Gaps = 1/153 (0%) Frame = -2 Query: 688 IDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAH 512 ID+ +K+ + V C N GD+ SD A GS+G++ S + K E A Sbjct: 226 IDNACMQIIKNPSQFDVLLCSNIFGDIISDECAMITGSIGMLPSASL-NSKKFGLYEPAG 284 Query: 511 GTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVES 332 G+ G+ N IA I + + + H L+ E A K++ + +++ Sbjct: 285 GSAP------DIEGKNIANPIAQILSLSMLIRHSMNLN------EIADKIDSSVYRALKA 332 Query: 331 GKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 233 G T D++ +Y+ T E D +A Sbjct: 333 GYRTLDIS---------DGKNYIKTNEMGDIIA 356
>LEU3_BRAJA (Q89X19) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 370 Score = 32.7 bits (73), Expect = 1.1 Identities = 33/107 (30%), Positives = 49/107 (45%), Gaps = 1/107 (0%) Frame = -2 Query: 628 NYDGDVQSDFLAQGFGSLGLMTSVLMCP-DGKTIEAEAAHGTVTRHFRVHQKGGETSTNS 452 N GD+ SD A GSLG++ S + D K+ + +A + V H G+ N Sbjct: 246 NLFGDMLSDIAAMLTGSLGMLPSASLGEVDVKSKKRKALYEPV--HGSAPDIAGKGLANP 303 Query: 451 IASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 311 IA I ++ G+A R D A A K++ A + SG T D+ Sbjct: 304 IAMISSF--GMALRYSFDMGA----LADKVDAAIAAVLASGLRTADI 344
>LEU3_ECOLI (P30125) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 32.7 bits (73), Expect = 1.1 Identities = 42/153 (27%), Positives = 62/153 (40%), Gaps = 1/153 (0%) Frame = -2 Query: 688 IDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAH 512 ID+ +K + V C N GD+ SD A GS+G++ S + G + E A Sbjct: 225 IDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YEPAG 283 Query: 511 GTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVES 332 G+ G+ N IA I + L + DD A +E A +E Sbjct: 284 GSAP------DIAGKNIANPIAQILSLALLLRYSLDADD------AACAIERAINRALEE 331 Query: 331 GKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 233 G T DLA G++ V +T+E D +A Sbjct: 332 GIRTGDLA---RGAAAV------STDEMGDIIA 355
>LEU3_ANASP (Q8YXA2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 32.7 bits (73), Expect = 1.1 Identities = 28/106 (26%), Positives = 46/106 (43%) Frame = -2 Query: 628 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 449 N GD+ SD A GS+G++ S + G + E HG+ G+ N + Sbjct: 246 NLFGDILSDAAAMLTGSIGMLPSASLGASGPGV-FEPVHGSAP------DIAGQDKANPL 298 Query: 448 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 311 A + + + R LD + A K+E+A + +E G T D+ Sbjct: 299 AQVL--SAAMMLRYALDQP----QAADKIEQAVLQVLEQGDRTGDI 338
>LEU3_SYNEL (P59029) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 361 Score = 32.7 bits (73), Expect = 1.1 Identities = 29/106 (27%), Positives = 45/106 (42%) Frame = -2 Query: 628 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 449 N GD+ SD A GS+G++ S + G + E HG+ G+ N + Sbjct: 246 NLFGDILSDIAAMLTGSIGMLPSASLGESGPAL-FEPVHGSAP------DIAGQDKANPL 298 Query: 448 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 311 A + + + R L+ A AQ +EEA ++ G T DL Sbjct: 299 AMVL--SAAMMLRYGLNQPAA----AQAIEEAITAVLDQGYRTGDL 338
>LEU3_THEMA (Q9WZ26) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 354 Score = 32.7 bits (73), Expect = 1.1 Identities = 33/107 (30%), Positives = 46/107 (42%) Frame = -2 Query: 628 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 449 N GD+ SD A GSLGL+ S G E A G+ G+ N I Sbjct: 239 NMFGDILSDESAALPGSLGLLPSASF---GDKNLYEPAGGSAP------DIAGKNIANPI 289 Query: 448 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLA 308 A I + L H + ++E A+K+E A +E G T+D+A Sbjct: 290 AQILSLAMMLEH------SFGMVEEARKIERAVELVIEEGYRTRDIA 330
>LEU3_PSEHT (Q3IJS3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 358 Score = 32.3 bits (72), Expect = 1.4 Identities = 36/120 (30%), Positives = 52/120 (43%), Gaps = 5/120 (4%) Frame = -2 Query: 643 VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGET 464 V C N GD+ SD A GS+GL+ S + G + E A G+ G+ Sbjct: 242 VLLCDNLFGDILSDECAMITGSMGLLPSASLNQSGFGL-YEPAGGSAP------DIAGKG 294 Query: 463 STNSIASIFAWTRGLAHRAKLDDNARLLEFA-QKLEEACVGTVE----SGKMTKDLALLV 299 N IA I + L + D+ AR +E A + A VGT + +G T D+A + Sbjct: 295 VANPIAQILSAALMLRYSLGQDEAARTIEKAVAEAVAAGVGTPDIFPNAGYTTNDVAAAI 354
>LEU3_GEOSL (Q748X2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 32.3 bits (72), Expect = 1.4 Identities = 35/135 (25%), Positives = 57/135 (42%) Frame = -2 Query: 634 CKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 455 C+N GD+ SD A GSLG++ S + +G E + G+ G+ N Sbjct: 245 CENMFGDILSDEAAMLTGSLGMLPSASLA-EGTFGMYEPSGGSAP------DIAGQGIAN 297 Query: 454 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTR 275 IA I L+ L + +++ A ++ A ++ G T+D+ G V Sbjct: 298 PIAQI------LSMGMMLKFSFGMVDAADAIDNAVATVLDQGFRTRDIYQQKDGEKLV-- 349 Query: 274 SDYLNTEEFIDAVAA 230 NT+E DA+ A Sbjct: 350 ----NTKEMGDAIIA 360
>ATG16_XENTR (Q5I0B9) Autophagy-related protein 16 (APG16-like 1)| Length = 537 Score = 32.0 bits (71), Expect = 1.8 Identities = 24/83 (28%), Positives = 36/83 (43%), Gaps = 7/83 (8%) Frame = -2 Query: 613 VQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTV-------TRHFRVHQKGGETSTN 455 VQ F A GF T V+ PDG + A +A GT+ + R+ K +S N Sbjct: 452 VQQTFSAPGFKCGSDWTRVIFSPDGSYVSAGSAEGTLYFWNVLTGKVERMFSKQHSSSIN 511 Query: 454 SIASIFAWTRGLAHRAKLDDNAR 386 ++ AW+ H +D +R Sbjct: 512 AV----AWSPSGTHVVSVDKGSR 530
>LEU3_MANSM (Q65V05) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 358 Score = 32.0 bits (71), Expect = 1.8 Identities = 35/128 (27%), Positives = 53/128 (41%), Gaps = 1/128 (0%) Frame = -2 Query: 688 IDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAH 512 ID+ +K+ + V C N GD+ SD A GS+G++ S + +G + E A Sbjct: 225 IDNATMQLIKAPESFDVLLCSNIFGDIISDEAAMITGSMGMLPSASLNEEGFGL-YEPAG 283 Query: 511 GTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVES 332 G+ G+ N IA I + L + L+ E A +E A + Sbjct: 284 GSAP------DIAGKGIANPIAQILSAAMMLRYSFNLN------EAATAIENAVQKVLAD 331 Query: 331 GKMTKDLA 308 G T DLA Sbjct: 332 GHRTGDLA 339
>LEU3_YERPS (Q66EM2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 32.0 bits (71), Expect = 1.8 Identities = 36/128 (28%), Positives = 50/128 (39%), Gaps = 1/128 (0%) Frame = -2 Query: 688 IDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAH 512 ID+ +K + V C N GD+ SD A GS+G++ S + G + E A Sbjct: 226 IDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YEPAG 284 Query: 511 GTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVES 332 G+ G+ N IA I + L DD A +E A +E Sbjct: 285 GSAP------DIAGKNIANPIAQILSLILLLRFSLGKDD------AADAIERAINQALEQ 332 Query: 331 GKMTKDLA 308 G T DLA Sbjct: 333 GYRTADLA 340
>LEU3_SHIBS (Q326G2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 32.0 bits (71), Expect = 1.8 Identities = 42/153 (27%), Positives = 62/153 (40%), Gaps = 1/153 (0%) Frame = -2 Query: 688 IDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAH 512 ID+ +K + V C N GD+ SD A GS+G++ S + G + E A Sbjct: 226 IDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YEPAG 284 Query: 511 GTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVES 332 G+ G+ N IA I + L + DD A +E A +E Sbjct: 285 GSAP------DITGKNIANPIAQILSLALLLRYSLDADD------AACAIERAINRALEE 332 Query: 331 GKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 233 G T DLA G++ V +T+E D +A Sbjct: 333 GIRTGDLA---RGAAAV------STDEMGDIIA 356
>LEU3_SALTI (Q8Z9I1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 32.0 bits (71), Expect = 1.8 Identities = 41/153 (26%), Positives = 62/153 (40%), Gaps = 1/153 (0%) Frame = -2 Query: 688 IDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAH 512 ID+ +K + V C N GD+ SD A GS+G++ S + + E A Sbjct: 226 IDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQEFGL-YEPAG 284 Query: 511 GTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVES 332 G+ G+ N IA I + L + D E A +E+A +E Sbjct: 285 GSAP------DIAGKNIANPIAQILSLALLLRYSLDAD------EAATAIEQAINRALEE 332 Query: 331 GKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 233 G T DLA G++ V +T+E D +A Sbjct: 333 GVRTSDLA---RGAAAV------STDEMGDIIA 356
>IDH_ECOLI (P08200) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 416 Score = 32.0 bits (71), Expect = 1.8 Identities = 34/136 (25%), Positives = 52/136 (38%) Frame = -2 Query: 643 VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGET 464 V AC N +GD SD LA G +G+ + + EA HGT ++ G+ Sbjct: 298 VIACMNLNGDYISDALAAQVGGIGIAPGANIGDECALF--EATHGTAPKY------AGQD 349 Query: 463 STNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSK 284 N + I + L H E A + + G + + +T D L+ G+ Sbjct: 350 KVNPGSIILSAEMMLRHMG-------WTEAADLIVKGMEGAINAKTVTYDFERLMDGAK- 401 Query: 283 VTRSDYLNTEEFIDAV 236 L EF DA+ Sbjct: 402 -----LLKCSEFGDAI 412
>LEU3_PELCD (Q3A3B2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 365 Score = 31.6 bits (70), Expect = 2.4 Identities = 40/139 (28%), Positives = 55/139 (39%) Frame = -2 Query: 643 VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGET 464 V C N GD+ SD A GSLG++ S + +G E A G+ G+ Sbjct: 242 VLLCPNMFGDILSDEAAMLTGSLGMLPSASLA-EGSFGMYEPAGGSAP------DIAGKN 294 Query: 463 STNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSK 284 N +A I + L + L D A +E K E C+ +G T D+ G Sbjct: 295 IANPVAQILSAAMLLRYSCGLADAADAVE---KAVENCLA---AGLRTGDIYQDADGEQL 348 Query: 283 VTRSDYLNTEEFIDAVAAE 227 V +T DAV AE Sbjct: 349 V------STSAMGDAVVAE 361
>LEU3_BUCUD (Q9EVE1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 31.6 bits (70), Expect = 2.4 Identities = 35/153 (22%), Positives = 63/153 (41%), Gaps = 1/153 (0%) Frame = -2 Query: 688 IDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAH 512 ID+ +K + + C N GD+ SD A GS+G++ S + + K E A Sbjct: 226 IDNATMQIIKDPNQFDILLCSNLFGDIISDECAIITGSIGMLPSASL-NEKKFGLYEPAG 284 Query: 511 GTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVES 332 G+ G+ N IA I + + + + L A K++++ + ++ Sbjct: 285 GSAP------DIEGKNIANPIAQILSVSMLVRY------GMNLKTIADKIDQSVISVLKK 332 Query: 331 GKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 233 G T D++ ++YL T E D +A Sbjct: 333 GYRTADIS---------NNNNYLKTNEMGDVIA 356
>LEU3_NITOC (Q3JCC4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 31.6 bits (70), Expect = 2.4 Identities = 30/106 (28%), Positives = 48/106 (45%) Frame = -2 Query: 628 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 449 N GD+ SD A GS+G++ S + G+ + E HG+ G+ N + Sbjct: 244 NMFGDILSDCAAMLTGSIGMLPSASLDQSGRGM-YEPIHGSAP------DIAGQGIANPL 296 Query: 448 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 311 A+I + L R LD A+ A +LE+A ++ G T D+ Sbjct: 297 ATILSVAMML--RYSLDSPAQ----ATRLEKAVGAVLDQGLRTPDI 336
>LEU3_METCA (Q606F4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 360 Score = 31.2 bits (69), Expect = 3.1 Identities = 30/107 (28%), Positives = 46/107 (42%) Frame = -2 Query: 628 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 449 N GD+ SD A GS+G++ S + GK + E HG+ G N I Sbjct: 244 NMFGDILSDCAAMLTGSIGMLPSASLAESGKGM-YEPIHGSAP------DIAGRGIANPI 296 Query: 448 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLA 308 A+I + L R DD A+++ +A ++ G T D+A Sbjct: 297 ATILSLAMML--RYSFDDAVS----AERIGKAVQTALDQGFRTADIA 337
>OM25_BRUCA (Q45110) 25 kDa outer-membrane immunogenic protein precursor| Length = 213 Score = 31.2 bits (69), Expect = 3.1 Identities = 34/131 (25%), Positives = 53/131 (40%), Gaps = 7/131 (5%) Frame = -2 Query: 682 DMVAYALKSEGGYVWACKNYDGDVQSDFLAQGF-GSLGLMTSVLMCPDGKTIEAEAAHGT 506 D + Y ++ + GY WA K+ DG + QGF GSL + P + A A Sbjct: 87 DQIVYGVEGDAGYSWAKKSKDGLE----VKQGFEGSLRARVGYDLNPVMPYLTAGIAGSQ 142 Query: 505 VTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNA------RLLEFAQKLEEACVG 344 + + + GE+ WT G AKL DN R +++ K + Sbjct: 143 IKLN---NGLDGESKFR-----VGWTAGAGLEAKLTDNILGRVEYRYTQYSNKNYDLAGT 194 Query: 343 TVESGKMTKDL 311 TV + T+D+ Sbjct: 195 TVRNKLDTQDI 205
>LEU3_BACSK (Q5WEN4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 364 Score = 30.8 bits (68), Expect = 4.1 Identities = 31/108 (28%), Positives = 45/108 (41%) Frame = -2 Query: 631 KNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNS 452 +N GD+ SD + GSLGL+ S M K E HG+ G + N Sbjct: 242 ENLFGDILSDEASMITGSLGLLPSASM-NTSKVGLFEPVHGSAP------DIAGTGAANP 294 Query: 451 IASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLA 308 +A+I + L + L D A+ +E A + G TKD+A Sbjct: 295 LATILSAAMMLQYSFGLADEAKAIEVAVD------RVLAQGVRTKDIA 336
>LEU3_SYNP6 (Q5MZ40) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 365 Score = 30.8 bits (68), Expect = 4.1 Identities = 28/106 (26%), Positives = 46/106 (43%) Frame = -2 Query: 628 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 449 N GD+ SD A GS+G++ S + +G + E HG+ G+ N + Sbjct: 246 NLFGDILSDIAAMLTGSIGMLPSASLGAEGPGV-FEPVHGSAP------DIAGQDKANPL 298 Query: 448 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 311 A + + + R LD+ E A ++E A ++ G T DL Sbjct: 299 AQVL--SAAMMLRYGLDEP----EAAARIEAAVNQVLDQGYRTGDL 338
>LEU3_SILPO (Q5LWZ5) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 367 Score = 30.8 bits (68), Expect = 4.1 Identities = 31/106 (29%), Positives = 43/106 (40%) Frame = -2 Query: 628 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 449 N GD+ SD A GSLG++ S + +A + V H G+ N I Sbjct: 244 NLFGDILSDCAAMLTGSLGMLPSASLGAPMANGRPKALYEPV--HGSAPDIAGQGKANPI 301 Query: 448 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 311 A I ++ +A R D A A +LE A + G T DL Sbjct: 302 ACILSF--AMALRYSFDQGAE----ADRLEAAVEQVLADGVRTADL 341
>LEU3_BUCBP (P59515) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 366 Score = 30.4 bits (67), Expect = 5.3 Identities = 38/153 (24%), Positives = 64/153 (41%), Gaps = 1/153 (0%) Frame = -2 Query: 688 IDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAH 512 +D+ +K+ + V C N GD+ SD A GS+GL+ S + D E A Sbjct: 226 VDNAAMQIIKNPSQFDVLLCSNLFGDILSDECAAITGSIGLLPSASL-NDKNFGLYEPAG 284 Query: 511 GTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVES 332 G+ G+ N IA I + + + KL D A L+++A T++ Sbjct: 285 GSAP------DIKGKNIANPIALILSIGMMMRYSFKLYDVADLIDWAVN------KTLKL 332 Query: 331 GKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 233 G T+D++ + ++NT D +A Sbjct: 333 GYRTQDIS---------ENNKFINTSSMGDIIA 356
>LEU3_SYMTH (Q67JY2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 368 Score = 30.4 bits (67), Expect = 5.3 Identities = 35/136 (25%), Positives = 51/136 (37%), Gaps = 9/136 (6%) Frame = -2 Query: 685 DDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLM--------CPDGKT 533 D+ L+ G + V N GD SD A GS+GL+ S + P G Sbjct: 228 DNAAMQILRRPGDFDVMLASNLFGDFLSDEAAMLTGSIGLLPSASLGAARNRFGLPKG-- 285 Query: 532 IEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEA 353 E HG+ G+ N +A+I L H +D AR +E+A Sbjct: 286 -FYEPIHGSAP------DIAGQDRANPLAAILCGAMLLRHSLGREDAAR------AVEQA 332 Query: 352 CVGTVESGKMTKDLAL 305 +E G T D+ + Sbjct: 333 VAAVLEEGLRTADITV 348
>LEU3_BUCUN (Q9EVI7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 364 Score = 30.4 bits (67), Expect = 5.3 Identities = 37/153 (24%), Positives = 63/153 (41%), Gaps = 1/153 (0%) Frame = -2 Query: 688 IDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAH 512 ID+ +K + V C N GD+ SD A GS+G++ S + + K E A Sbjct: 227 IDNATMQIIKDPNQFDVLLCSNLFGDIISDECAIITGSIGMLPSASL-NEKKFGLYEPAG 285 Query: 511 GTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVES 332 G+ G+ N IA I + + + + + L A K++ + + ++ Sbjct: 286 GSAP------DIEGKNIANPIAQILSVSMLVRY------SMNLKNIADKIDYSVISILKK 333 Query: 331 GKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 233 G T D+A ++YL T E D +A Sbjct: 334 GYKTADIA---------HDNNYLKTNEMGDVIA 357
>LEU3_PSEF5 (Q4KF05) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 360 Score = 30.4 bits (67), Expect = 5.3 Identities = 35/133 (26%), Positives = 58/133 (43%) Frame = -2 Query: 628 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 449 N GD+ SD + GS+G++ S + + K + E HG+ G+ N + Sbjct: 244 NMFGDILSDEASMLTGSIGMLPSASLDANNKGM-YEPCHGSAP------DIAGQGIANPL 296 Query: 448 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTRSD 269 A+I + + L + + L E A +E+A ++ G T D + G +KV Sbjct: 297 ATILSVSMMLRY------SFNLTEAADAIEQAVSRVLDQGLRTGD--IWSAGCTKV---- 344 Query: 268 YLNTEEFIDAVAA 230 T+E DAV A Sbjct: 345 --GTQEMGDAVVA 355
>LEU3_RALSO (Q8XXX5) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 356 Score = 30.4 bits (67), Expect = 5.3 Identities = 38/127 (29%), Positives = 55/127 (43%), Gaps = 22/127 (17%) Frame = -2 Query: 643 VWACKNYD--------GDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFR 488 V A KN+D GD+ SD A GS+G++ S + + K + E +HG+ Sbjct: 230 VKAPKNFDVVVTGNMFGDILSDEAAMLTGSIGMLPSASLDANNKGL-YEPSHGSAP---- 284 Query: 487 VHQKGGETSTNSIASIFA------WTRGLAHRAKLDDNARLLEFAQK------LEEAC-- 350 G+ N +A+I + +T G A +A +NA AQ L C Sbjct: 285 --DIAGKGIANPLATILSAAMMLRYTLGKAEQADRIENAVKKVLAQGYRTGDILTPGCKQ 342 Query: 349 VGTVESG 329 VGTVE G Sbjct: 343 VGTVEMG 349
>LEU3_PSYAR (Q4FRV0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 367 Score = 30.4 bits (67), Expect = 5.3 Identities = 28/106 (26%), Positives = 46/106 (43%) Frame = -2 Query: 628 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 449 N GD+ SD A GS+G++ S + GK + E HG+ G+ N + Sbjct: 250 NLFGDILSDEAAMLTGSIGMLPSASLDEAGKGM-YEPCHGSAP------DIAGQDIANPL 302 Query: 448 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 311 A+I + L + K + AQ +E+A ++ G T D+ Sbjct: 303 ATILSVAMMLRYTFKQE------VAAQAIEQAVSDVLDDGLRTVDI 342
>LEU3_GLUOX (Q5FUG5) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 369 Score = 30.4 bits (67), Expect = 5.3 Identities = 26/90 (28%), Positives = 40/90 (44%), Gaps = 4/90 (4%) Frame = -2 Query: 628 NYDGDVQSDFLAQGFGSLGLMTSVLMCP---DGK-TIEAEAAHGTVTRHFRVHQKGGETS 461 N GD+ SD + GSLG++ S + P DGK E HG+ G+ Sbjct: 247 NLFGDILSDLASMLTGSLGMLPSATLGPVRADGKRNALYEPIHGSAP------DIAGKGI 300 Query: 460 TNSIASIFAWTRGLAHRAKLDDNARLLEFA 371 N +A I ++ L + ++A L+E A Sbjct: 301 ANPLAQILSFAMLLRYSLNRAEDADLIEMA 330
>LEU3_ACIAD (Q6FEV6) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 359 Score = 30.4 bits (67), Expect = 5.3 Identities = 31/115 (26%), Positives = 51/115 (44%), Gaps = 14/115 (12%) Frame = -2 Query: 628 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 449 N GD+ SD A GS+G++ S + +GK + E HG+ G+ N + Sbjct: 245 NLFGDILSDEAAMLTGSIGMLPSASLDENGKGM-YEPCHGSAP------DIAGQNVANPL 297 Query: 448 ASIFAWTRGLAHRAKLDDNARLLEFA--QKLEEAC------------VGTVESGK 326 A+I + L + + + A+ +E A Q L++ VGTVE G+ Sbjct: 298 ATILSVAMMLRYTFREEAAAKAIEDAVGQVLDQGLRTADIMSEGMQRVGTVEMGQ 352
>INHBA_SHEEP (P43032) Inhibin beta A chain precursor (Activin beta-A chain)| Length = 425 Score = 30.4 bits (67), Expect = 5.3 Identities = 24/97 (24%), Positives = 49/97 (50%), Gaps = 1/97 (1%) Frame = -2 Query: 526 AEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTR-GLAHRAKLDDNARLLEFAQKLEEAC 350 AE+ T HF + Q+G + S A I+ + + A+R + RL + + L+ Sbjct: 127 AESGTARKTLHFEISQEGSDLSVVERAEIWLFLKVPKANRTRSKVTIRLFQQQKHLQ--- 183 Query: 349 VGTVESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDA 239 G++++G+ +++ L K +S+ L +E+ +DA Sbjct: 184 -GSLDAGEEAEEVGL------KGEKSEMLISEKVVDA 213
>LEU3_SOLTU (P29696) 3-isopropylmalate dehydrogenase, chloroplast precursor (EC| 1.1.1.85) (Beta-IPM dehydrogenase) (IMDH) (3-IPM-DH) Length = 357 Score = 30.4 bits (67), Expect = 5.3 Identities = 28/102 (27%), Positives = 43/102 (42%) Frame = -2 Query: 628 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 449 N GD+ SD A G LGL S + G + AEA HG+ G+ N Sbjct: 258 NLYGDIISDLCAGLIGGLGLTPSCNIGEGGIAL-AEAVHGSAP------DIAGKNLANPT 310 Query: 448 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKM 323 A + + L H L + A ++++A + T+ GK+ Sbjct: 311 ALLLSSVSMLRH-------LELHDKADRIQDAILKTIAGGKV 345
>LEU3_PROMP (Q7V1R9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 357 Score = 30.4 bits (67), Expect = 5.3 Identities = 31/127 (24%), Positives = 51/127 (40%), Gaps = 1/127 (0%) Frame = -2 Query: 688 IDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAH 512 +D+ +K G + V N GD+ SD A GS+G++ S + G + E H Sbjct: 223 VDNAAMQLVKDPGQFDVILTSNLFGDILSDLAAMITGSIGMLPSASLSNSGPGV-FEPVH 281 Query: 511 GTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVES 332 G+ + + +IA+ A + K+ N +E A +E A + Sbjct: 282 GSAP----------DIAGKNIANPIAMALSTSMMLKIGLNE--IEAADDIEIAIDNVLSK 329 Query: 331 GKMTKDL 311 G T DL Sbjct: 330 GYRTSDL 336
>LEU3_BUCUL (Q9AQC8) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) (Fragment) Length = 126 Score = 30.4 bits (67), Expect = 5.3 Identities = 31/134 (23%), Positives = 55/134 (41%) Frame = -2 Query: 634 CKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 455 C N GD+ SD A GS+G++ S + E A G+ G+ N Sbjct: 8 CSNLFGDIISDECAVITGSIGMLPSASFNEKNFGL-YEPAGGSAP------DIAGKNIAN 60 Query: 454 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTR 275 IA I + + + + KL + A K++++ +++G T D++ Sbjct: 61 PIAQILSLSMLVRYGMKLK------KIADKIDKSVASALKAGYRTADIS---------NN 105 Query: 274 SDYLNTEEFIDAVA 233 + YL T E D ++ Sbjct: 106 NSYLKTNEMGDVIS 119
>LEU3_BACCZ (Q63DX7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 354 Score = 30.4 bits (67), Expect = 5.3 Identities = 33/127 (25%), Positives = 55/127 (43%), Gaps = 1/127 (0%) Frame = -2 Query: 688 IDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAH 512 +D +++ G + V +N GD+ SD + GSLG++ S G ++ E H Sbjct: 214 VDAAAMELIRNPGRFDVIVTENLFGDILSDEASVLAGSLGMLPSASHAEKGPSL-YEPIH 272 Query: 511 GTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVES 332 G+ G+ N IA + R +A L + L +EEA ++S Sbjct: 273 GSAP------DIAGKNKANPIAMM----RSVA--MMLGQSFGLTREGCAIEEAISAVLKS 320 Query: 331 GKMTKDL 311 GK T+D+ Sbjct: 321 GKCTEDI 327
>LEU3_BACCR (Q81G11) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 354 Score = 30.4 bits (67), Expect = 5.3 Identities = 33/127 (25%), Positives = 54/127 (42%), Gaps = 1/127 (0%) Frame = -2 Query: 688 IDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAH 512 +D +++ G + V +N GD+ SD + GSLG++ S G ++ E H Sbjct: 214 VDAAAMELIRNPGRFDVIVTENLFGDILSDEASVLAGSLGMLPSASHAEKGPSL-YEPIH 272 Query: 511 GTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVES 332 G+ G+ N IA + R +A L + L +EEA ++S Sbjct: 273 GSAP------DIAGKNKANPIAMM----RSVA--MMLGQSFGLTREGYAIEEAVSAVLKS 320 Query: 331 GKMTKDL 311 GK T D+ Sbjct: 321 GKCTADI 327
>LEU3_OCEIH (Q8EN68) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 366 Score = 30.0 bits (66), Expect = 7.0 Identities = 26/87 (29%), Positives = 39/87 (44%) Frame = -2 Query: 631 KNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNS 452 +N GD+ SD + GSLG++ S + DG + E HG+ G+ N Sbjct: 238 ENLFGDILSDEASVLTGSLGMLPSASLRADGLGL-YEPVHGSAP------DIAGKGIANP 290 Query: 451 IASIFAWTRGLAHRAKLDDNARLLEFA 371 +A I + L H L D A+ +E A Sbjct: 291 LAMILSAALMLEHSFGLVDEAKEIERA 317
>LEU3_GEOKA (Q5KWJ4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 371 Score = 30.0 bits (66), Expect = 7.0 Identities = 30/108 (27%), Positives = 46/108 (42%) Frame = -2 Query: 631 KNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNS 452 +N GD+ SD + GSLG++ S + G ++ E HG+ G N Sbjct: 243 ENMFGDILSDEASMLSGSLGMLPSASLSASGPSL-YEPVHGSAP------DIAGMNKANP 295 Query: 451 IASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLA 308 IA+I L+ L + L A+ +E A ++ G T DLA Sbjct: 296 IAAI------LSAAMMLRLSFGLTAEAEAVEHAVRQALDQGLRTADLA 337
>Y1185_METJA (Q58585) Hypothetical protein MJ1185| Length = 622 Score = 30.0 bits (66), Expect = 7.0 Identities = 22/62 (35%), Positives = 34/62 (54%) Frame = -3 Query: 546 LMVKQSKPKLPMAQSLVISVFTRKVVKPAQTALLPSLLGQEDLHTGQS*TTTLDFLNLHR 367 L+V+ K +LP+ ++L I F RK +KP L+ LLG ED+ D +NL+R Sbjct: 504 LVVESIKLELPI-ENLGICRFHRKWLKPVLKELVKELLGIEDI--------VEDSINLYR 554 Query: 366 NL 361 + Sbjct: 555 EI 556
>OM25_BRUSU (Q45689) 25 kDa outer-membrane immunogenic protein precursor| Length = 213 Score = 30.0 bits (66), Expect = 7.0 Identities = 33/131 (25%), Positives = 52/131 (39%), Gaps = 7/131 (5%) Frame = -2 Query: 682 DMVAYALKSEGGYVWACKNYDGDVQSDFLAQGF-GSLGLMTSVLMCPDGKTIEAEAAHGT 506 D + Y ++ + GY WA K+ DG + QGF GSL + P + A G Sbjct: 87 DQIVYGVEGDAGYSWAKKSKDGLE----VKQGFEGSLRARVGYDLNPVMPYLTA----GI 138 Query: 505 VTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNA------RLLEFAQKLEEACVG 344 +++ + S + WT G AKL DN R ++ K + Sbjct: 139 AGSQIKLNNGLDDESKFRV----GWTAGAGLEAKLTDNILGRVEYRYTQYGNKNYDLAGT 194 Query: 343 TVESGKMTKDL 311 TV + T+D+ Sbjct: 195 TVRNKLDTQDI 205
>OM25_BRUAB (Q44664) 25 kDa outer-membrane immunogenic protein precursor| Length = 213 Score = 30.0 bits (66), Expect = 7.0 Identities = 33/131 (25%), Positives = 52/131 (39%), Gaps = 7/131 (5%) Frame = -2 Query: 682 DMVAYALKSEGGYVWACKNYDGDVQSDFLAQGF-GSLGLMTSVLMCPDGKTIEAEAAHGT 506 D + Y ++ + GY WA K+ DG + QGF GSL + P + A G Sbjct: 87 DQIVYGVEGDAGYSWAKKSKDGLE----VKQGFEGSLRARVGYDLNPVMPYLTA----GI 138 Query: 505 VTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNA------RLLEFAQKLEEACVG 344 +++ + S + WT G AKL DN R ++ K + Sbjct: 139 AGSQIKLNNGLDDESKFRV----GWTAGAGLEAKLTDNILGRVEYRYTQYGNKNYDLAGT 194 Query: 343 TVESGKMTKDL 311 TV + T+D+ Sbjct: 195 TVRNKLDTQDI 205
>LEU3_PROMT (Q46LE2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 359 Score = 29.6 bits (65), Expect = 9.1 Identities = 30/106 (28%), Positives = 42/106 (39%) Frame = -2 Query: 628 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 449 N GD+ SD A GS+G++ S + DG + E HG+ + + I Sbjct: 244 NLFGDILSDIAAMLTGSIGMLPSASLTTDGPGV-FEPVHGSAP----------DIAGKDI 292 Query: 448 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 311 A+ A A K+ N E A LE A + G T DL Sbjct: 293 ANPIAMLLSAAMMLKIALNE--TEAATFLENAINEILNDGYRTSDL 336
>SYNJ1_BOVIN (O18964) Synaptojanin-1 (EC 3.1.3.36) (Synaptic| inositol-1,4,5-trisphosphate 5-phosphatase 1) (p150) (Fragment) Length = 1324 Score = 29.6 bits (65), Expect = 9.1 Identities = 28/88 (31%), Positives = 39/88 (44%), Gaps = 12/88 (13%) Frame = -2 Query: 505 VTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLE-------FAQKLEEA-- 353 VTR V + + +SI+ I+A T L +AKL D AR + F +EA Sbjct: 418 VTRFQEVFRSMWSVNGDSISKIYAGTGALEGKAKLKDGARSVSRTIQNNFFDSSKQEAID 477 Query: 352 ---CVGTVESGKMTKDLALLVHGSSKVT 278 T+ S K ALL GS +V+ Sbjct: 478 VLLLGNTLNSDLADKARALLTTGSLRVS 505
>LEU3_NEILA (P50180) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) (Fragment) Length = 313 Score = 29.6 bits (65), Expect = 9.1 Identities = 26/85 (30%), Positives = 40/85 (47%) Frame = -2 Query: 643 VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGET 464 V A N GD+ SD + GSLG++ S + +GK + E +HG+ G+ Sbjct: 238 VIATGNIFGDILSDEASMLTGSLGMLPSASLDENGKGL-YEPSHGSAP------DIAGQN 290 Query: 463 STNSIASIFAWTRGLAHRAKLDDNA 389 N +A+I + L R L+D A Sbjct: 291 KANPLATILSLAMLL--RYSLNDEA 313
>LEU3_BACHK (Q6HLF2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 354 Score = 29.6 bits (65), Expect = 9.1 Identities = 33/127 (25%), Positives = 54/127 (42%), Gaps = 1/127 (0%) Frame = -2 Query: 688 IDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAH 512 +D +++ G + V +N GD+ SD + GSLG++ S G ++ E H Sbjct: 214 VDAAAMELIRNPGRFDVIVTENLFGDILSDEASVLAGSLGMLPSASHAEKGPSL-YEPIH 272 Query: 511 GTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVES 332 G+ G+ N IA + R +A L + L +EEA ++S Sbjct: 273 GSAP------DIAGKNKANPIAMM----RSVA--MMLGQSFGLTREGCAIEEAISAVLKS 320 Query: 331 GKMTKDL 311 GK T D+ Sbjct: 321 GKCTADI 327
>LEU3_BACAN (Q81T67) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 354 Score = 29.6 bits (65), Expect = 9.1 Identities = 33/127 (25%), Positives = 54/127 (42%), Gaps = 1/127 (0%) Frame = -2 Query: 688 IDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAH 512 +D +++ G + V +N GD+ SD + GSLG++ S G ++ E H Sbjct: 214 VDAAAMELIRNPGRFDVIVTENLFGDILSDEASVLAGSLGMLPSASHAEKGPSL-YEPIH 272 Query: 511 GTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVES 332 G+ G+ N IA + R +A L + L +EEA ++S Sbjct: 273 GSAP------DIAGKNKANPIAMM----RSVA--MMLGQSFGLTREGCAIEEAISAVLKS 320 Query: 331 GKMTKDL 311 GK T D+ Sbjct: 321 GKCTADI 327 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 89,590,510 Number of Sequences: 219361 Number of extensions: 1686290 Number of successful extensions: 4753 Number of sequences better than 10.0: 137 Number of HSP's better than 10.0 without gapping: 4594 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4721 length of database: 80,573,946 effective HSP length: 108 effective length of database: 56,882,958 effective search space used: 6882837918 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
