ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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更新日：2016年5月1日

Clone Information

BLAST Search Result

Clone Name rbags12f10
Clone Library Name barley_pub
No. Definition Score
(bits)		 E
Value
1IDHC_SOYBN (Q06197) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42... 245 8e-65
2IDHP_MEDSA (Q40345) Isocitrate dehydrogenase [NADP], chloroplast... 245 8e-65
3IDHC_TOBAC (P50218) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42... 238 8e-63
4IDHC_SOLTU (P50217) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42... 236 5e-62
5IDHC_MICOH (Q9Z2K8) Isocitrate dehydrogenase [NADP] cytoplasmic ... 201 1e-51
6IDHC_MICME (Q9Z2K9) Isocitrate dehydrogenase [NADP] cytoplasmic ... 201 1e-51
7IDHC_RAT (P41562) Isocitrate dehydrogenase [NADP] cytoplasmic (E... 200 3e-51
8IDHP_PIG (P33198) Isocitrate dehydrogenase [NADP], mitochondrial... 199 5e-51
9IDHP_BOVIN (Q04467) Isocitrate dehydrogenase [NADP], mitochondri... 199 5e-51
10IDHC_MOUSE (O88844) Isocitrate dehydrogenase [NADP] cytoplasmic ... 199 5e-51
11IDHP_HUMAN (P48735) Isocitrate dehydrogenase [NADP], mitochondri... 199 7e-51
12IDHC_HUMAN (O75874) Isocitrate dehydrogenase [NADP] cytoplasmic ... 197 2e-50
13IDHP_MOUSE (P54071) Isocitrate dehydrogenase [NADP], mitochondri... 183 3e-46
14IDH_MYCTU (P65097) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)... 183 4e-46
15IDH_MYCBO (P65098) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)... 183 4e-46
16IDH1_CANTR (O13285) Isocitrate dehydrogenase [NADP], mitochondri... 176 4e-44
17IDHC_YEAST (P41939) Isocitrate dehydrogenase [NADP] cytoplasmic ... 175 1e-43
18IDHH_YEAST (P53982) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42... 174 1e-43
19IDH_SPHYA (P50215) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)... 174 2e-43
20IDH2_CANTR (O13294) Isocitrate dehydrogenase [NADP] peroxisomal ... 173 4e-43
21IDHP_SCHPO (O14254) Probable isocitrate dehydrogenase [NADP], mi... 166 4e-41
22IDHP_YEAST (P21954) Isocitrate dehydrogenase [NADP], mitochondri... 165 8e-41
23IDHP_ASPNG (P79089) Isocitrate dehydrogenase [NADP], mitochondri... 155 9e-38
24LEU3_CAMJR (Q5HS77) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 39 0.015
25LEU3_CAMJE (Q9PLW0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 39 0.015
26IDH3A_RAT (Q99NA5) Isocitrate dehydrogenase [NAD] subunit alpha,... 38 0.026
27IDH3A_BOVIN (P41563) Isocitrate dehydrogenase [NAD] subunit alph... 38 0.026
28IDH3A_MOUSE (Q9D6R2) Isocitrate dehydrogenase [NAD] subunit alph... 37 0.045
29LEU3_NEIMB (Q9JZI9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 35 0.17
30LEU3_SHEON (Q8E9N3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 34 0.38
31LEU3_NEIMA (Q9JU79) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 34 0.38
32LEU3_BUCUE (Q9EVH5) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 33 0.50
33LEU3_BUCUA (Q9EVG6) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 33 0.65
34LEU3_PHOPR (Q6LV25) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 33 0.65
35LEU3_NEIG1 (Q5F8T6) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 33 0.65
36LEU3_LEPIN (P24015) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 33 0.85
37LEU3_LEPIC (Q72RH7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 33 0.85
38LEU3_DESPS (Q6ANR1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 32 1.1
39LEU3_ZYMMO (Q5NPQ9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 32 1.4
40ATG16_XENTR (Q5I0B9) Autophagy-related protein 16 (APG16-like 1) 32 1.4
41LEU3_PASMU (Q9CJN6) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 32 1.4
42LEU3_BACSU (P05645) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 32 1.4
43LEU3_BACLD (Q65GI9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 32 1.4
44LEU3_SHIDS (Q32K21) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 32 1.9
45LEU3_SALTY (P37412) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 31 2.5
46LEU3_SALPA (Q5PDG2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 31 2.5
47LEU3_SALCH (Q57TE7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 31 2.5
48LEU3_CAUCR (Q9ABN3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 31 2.5
49LEU3_COLP3 (Q47WG3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 31 2.5
50INHBA_SHEEP (P43032) Inhibin beta A chain precursor (Activin bet... 30 4.2
51LEU3_YERPE (Q8ZIG9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 30 4.2
52LEU3_BUCUS (Q9EVI4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 30 4.2
53LEU3_VIBPA (Q87SS8) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 30 5.5
54LEU3_ERWCT (Q6D0G7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 30 5.5
55Y1185_METJA (Q58585) Hypothetical protein MJ1185 30 5.5
56LEU3_THEMA (Q9WZ26) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 30 5.5
57LEU3_BUCUO (Q9EVI1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 30 5.5
58LEU3_SHIFL (Q83SP1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 30 5.5
59LEU3_ECOL6 (Q8FL76) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 30 5.5
60LEU3_ECO57 (Q8X9Z9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 30 5.5
61LEU3_STAAW (Q8NVJ0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 30 5.5
62LEU3_STAAS (Q6G7Q0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 30 5.5
63LEU3_STAAN (P65101) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 30 5.5
64LEU3_STAAM (P65100) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 30 5.5
65LEU3_STAAC (Q5HEE3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 30 5.5
66LEU3_HAEIN (P43860) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 30 5.5
67LEU3_VIBVY (Q7MP78) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 30 7.2
68LEU3_VIBVU (Q8DEE0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 30 7.2
69LEU3_VIBCH (Q9KP82) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 30 7.2
70LEU3_BUCDN (O85071) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 30 7.2
71SYNJ1_BOVIN (O18964) Synaptojanin-1 (EC 3.1.3.36) (Synaptic inos... 30 7.2
72LEU3_GEOSL (Q748X2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 30 7.2
73TPM1_SCHMA (P42637) Tropomyosin 1 (TMI) (Polypeptide 49) 29 9.4
74FST_BRARE (Q9YHV4) Follistatin precursor (FS) (Activin-binding p... 29 9.4
75LEU3_PHOLL (Q7N128) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 29 9.4
76LEU3_BUCUM (Q9EVG9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 29 9.4
77LEU3_BUCUH (Q9EVH8) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 29 9.4
78LEU3_PSEHT (Q3IJS3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 29 9.4
79SYNJ1_RAT (Q62910) Synaptojanin-1 (EC 3.1.3.36) (Synaptic inosit... 29 9.4
80SYNJ1_MOUSE (Q8CHC4) Synaptojanin-1 (EC 3.1.3.36) (Synaptic inos... 29 9.4
81SYNJ1_HUMAN (O43426) Synaptojanin-1 (EC 3.1.3.36) (Synaptic inos... 29 9.4 
>IDHC_SOYBN (Q06197) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
           ICDH) (IDP)
          Length = 413

 Score =  245 bits (625), Expect = 8e-65
 Identities = 120/137 (87%), Positives = 130/137 (94%)
 Frame = -2

Query: 609 ACKNYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETST 430
           ACKNYD DVQSDFLAQGFGSLGLMTSVL+CPDGKTIEAEAAHGTVTRHFRVHQKGGETST
Sbjct: 271 ACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHFRVHQKGGETST 330

Query: 429 NSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVT 250
           NSIASIFAWTRGLAHRAKLDDNA+LL+F +KLE AC+G VE+GKMTKDLAL++HG SK++
Sbjct: 331 NSIASIFAWTRGLAHRAKLDDNAKLLDFTEKLEAACIGVVEAGKMTKDLALILHG-SKLS 389

Query: 249 RSDYLNTEEFIDAVAAE 199
           R  YLNTEEFIDAVAAE
Sbjct: 390 REHYLNTEEFIDAVAAE 406
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>IDHP_MEDSA (Q40345) Isocitrate dehydrogenase [NADP], chloroplast precursor (EC|
           1.1.1.42) (Oxalosuccinate decarboxylase) (IDH)
           (NADP(+)-specific ICDH) (IDP) (Fragment)
          Length = 433

 Score =  245 bits (625), Expect = 8e-65
 Identities = 121/137 (88%), Positives = 129/137 (94%)
 Frame = -2

Query: 609 ACKNYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETST 430
           ACKNYD DVQSDFLAQGFGSLGLMTSVL+CPDGKTIEAEAAHGTVTRHFRVHQKGGETST
Sbjct: 291 ACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHFRVHQKGGETST 350

Query: 429 NSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVT 250
           NSIASIFAWTRGLAHRAKLDDNA LL+F +KLE AC+G VESGKMTKDLAL++HG SK++
Sbjct: 351 NSIASIFAWTRGLAHRAKLDDNATLLDFTEKLEAACIGVVESGKMTKDLALILHG-SKLS 409

Query: 249 RSDYLNTEEFIDAVAAE 199
           R  YLNTEEFIDAVAAE
Sbjct: 410 REHYLNTEEFIDAVAAE 426
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>IDHC_TOBAC (P50218) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
           ICDH) (IDP)
          Length = 415

 Score =  238 bits (608), Expect = 8e-63
 Identities = 117/137 (85%), Positives = 127/137 (92%)
 Frame = -2

Query: 609 ACKNYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETST 430
           ACKNYD DVQSDFLAQGFGSLGLMTSVL+CPDGKTIEAEAAHGTVTRH+RVHQKGGETST
Sbjct: 270 ACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYRVHQKGGETST 329

Query: 429 NSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVT 250
           NSIASIFAWTRGLAHRA LD+N RLL+F +KLE AC+G VESGKMTKDLAL++HG SK++
Sbjct: 330 NSIASIFAWTRGLAHRATLDNNERLLDFTEKLEAACIGAVESGKMTKDLALIIHG-SKLS 388

Query: 249 RSDYLNTEEFIDAVAAE 199
           R  YLNTEEFIDAVA E
Sbjct: 389 RDHYLNTEEFIDAVADE 405
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>IDHC_SOLTU (P50217) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
           ICDH) (IDP)
          Length = 416

 Score =  236 bits (601), Expect = 5e-62
 Identities = 115/137 (83%), Positives = 125/137 (91%)
 Frame = -2

Query: 609 ACKNYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETST 430
           ACKNYD DVQSDFLAQGFGSLGLMTSVL+CPDGKTIEAEAAHGTVTRH+RVHQKGGETST
Sbjct: 270 ACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYRVHQKGGETST 329

Query: 429 NSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVT 250
           NSIASIFAWTRGLAHRA LD+N RLL+F +KLE AC+G VESGKMTKDLAL++   SK++
Sbjct: 330 NSIASIFAWTRGLAHRATLDNNERLLDFTEKLEAACIGAVESGKMTKDLALIIIHGSKLS 389

Query: 249 RSDYLNTEEFIDAVAAE 199
           R  YLNTEEFIDAVA E
Sbjct: 390 REHYLNTEEFIDAVADE 406
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>IDHC_MICOH (Q9Z2K8) Isocitrate dehydrogenase [NADP] cytoplasmic (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
           ICDH) (IDP)
          Length = 414

 Score =  201 bits (512), Expect = 1e-51
 Identities = 96/132 (72%), Positives = 112/132 (84%)
 Frame = -2

Query: 609 ACKNYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETST 430
           ACKNYD DVQSD +AQG+GSLG+MTSVL+CPDGKT+EAEAAHGTVTRH+R+HQKG ETST
Sbjct: 268 ACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDGKTVEAEAAHGTVTRHYRMHQKGQETST 327

Query: 429 NSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVT 250
           N IASIFAW+RGLAHRA+LD+N  L  FA+ LEE C+ T+E+G MTKDLA  + G   V 
Sbjct: 328 NPIASIFAWSRGLAHRARLDNNTELSFFAKALEEVCIETIEAGFMTKDLAACIKGLPNVQ 387

Query: 249 RSDYLNTEEFID 214
           RSDYLNT EF+D
Sbjct: 388 RSDYLNTFEFMD 399
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>IDHC_MICME (Q9Z2K9) Isocitrate dehydrogenase [NADP] cytoplasmic (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
           ICDH) (IDP)
          Length = 414

 Score =  201 bits (512), Expect = 1e-51
 Identities = 96/132 (72%), Positives = 112/132 (84%)
 Frame = -2

Query: 609 ACKNYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETST 430
           ACKNYD DVQSD +AQG+GSLG+MTSVL+CPDGKT+EAEAAHGTVTRH+R+HQKG ETST
Sbjct: 268 ACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDGKTVEAEAAHGTVTRHYRMHQKGQETST 327

Query: 429 NSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVT 250
           N IASIFAW+RGLAHRA+LD+N  L  FA+ LEE C+ T+E+G MTKDLA  + G   V 
Sbjct: 328 NPIASIFAWSRGLAHRARLDNNTELSFFAKALEEVCIETIEAGFMTKDLAACIKGLPNVQ 387

Query: 249 RSDYLNTEEFID 214
           RSDYLNT EF+D
Sbjct: 388 RSDYLNTFEFMD 399
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>IDHC_RAT (P41562) Isocitrate dehydrogenase [NADP] cytoplasmic (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
           ICDH) (IDP)
          Length = 414

 Score =  200 bits (508), Expect = 3e-51
 Identities = 96/132 (72%), Positives = 111/132 (84%)
 Frame = -2

Query: 609 ACKNYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETST 430
           ACKNYD DVQSD +AQG+GSLG+MTSVL+CPDGKT+EAEAAHGTVTRH+R++QKG ETST
Sbjct: 268 ACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDGKTVEAEAAHGTVTRHYRMYQKGQETST 327

Query: 429 NSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVT 250
           N IASIFAW+RGLAHRAKLD+N  L  FA  LEE C+ T+E+G MTKDLA  + G   V 
Sbjct: 328 NPIASIFAWSRGLAHRAKLDNNTELSFFANALEEVCIETIEAGFMTKDLAACIKGLPNVQ 387

Query: 249 RSDYLNTEEFID 214
           RSDYLNT EF+D
Sbjct: 388 RSDYLNTFEFMD 399
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>IDHP_PIG (P33198) Isocitrate dehydrogenase [NADP], mitochondrial precursor|
           (EC 1.1.1.42) (Oxalosuccinate decarboxylase) (IDH)
           (NADP(+)-specific ICDH) (IDP) (ICD-M) (Fragment)
          Length = 421

 Score =  199 bits (506), Expect = 5e-51
 Identities = 99/135 (73%), Positives = 110/135 (81%), Gaps = 1/135 (0%)
 Frame = -2

Query: 609 ACKNYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETST 430
           ACKNYD DVQSD LAQGFGSLGLMTSVL+CPDGKTIEAEAAHGTVTRH+R HQKG  TST
Sbjct: 276 ACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTST 335

Query: 429 NSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVT 250
           N IASIFAWTRGL HR KLD N  L+ FAQ LE+ CV TVESG MTKDLA  +HG S V 
Sbjct: 336 NPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEKVCVETVESGAMTKDLAGCIHGLSNVK 395

Query: 249 RSD-YLNTEEFIDAV 208
            ++ +LNT +F+D +
Sbjct: 396 LNEHFLNTSDFLDTI 410
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>IDHP_BOVIN (Q04467) Isocitrate dehydrogenase [NADP], mitochondrial precursor|
           (EC 1.1.1.42) (Oxalosuccinate decarboxylase) (IDH)
           (NADP(+)-specific ICDH) (IDP) (ICD-M)
          Length = 452

 Score =  199 bits (506), Expect = 5e-51
 Identities = 99/135 (73%), Positives = 110/135 (81%), Gaps = 1/135 (0%)
 Frame = -2

Query: 609 ACKNYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETST 430
           ACKNYD DVQSD LAQGFGSLGLMTSVL+CPDGKTIEAEAAHGTVTRH+R HQKG  TST
Sbjct: 307 ACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTST 366

Query: 429 NSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVT 250
           N IASIFAWTRGL HR KLD N  L+ FAQ LE+ CV TVESG MTKDLA  +HG S V 
Sbjct: 367 NPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEKVCVETVESGAMTKDLAGCIHGLSNVK 426

Query: 249 RSD-YLNTEEFIDAV 208
            ++ +LNT +F+D +
Sbjct: 427 LNEHFLNTSDFLDTI 441
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>IDHC_MOUSE (O88844) Isocitrate dehydrogenase [NADP] cytoplasmic (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
           ICDH) (IDP)
          Length = 414

 Score =  199 bits (506), Expect = 5e-51
 Identities = 95/132 (71%), Positives = 112/132 (84%)
 Frame = -2

Query: 609 ACKNYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETST 430
           ACKNYD DVQSD +AQG+GSLG+MTSVL+CPDGKT+EAEAAHGTVTRH+R++QKG ETST
Sbjct: 268 ACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDGKTVEAEAAHGTVTRHYRMYQKGQETST 327

Query: 429 NSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVT 250
           N IASIFAW+RGLAHRAKLD+N  L  FA+ LE+ C+ T+E+G MTKDLA  + G   V 
Sbjct: 328 NPIASIFAWSRGLAHRAKLDNNTELSFFAKALEDVCIETIEAGFMTKDLAACIKGLPNVQ 387

Query: 249 RSDYLNTEEFID 214
           RSDYLNT EF+D
Sbjct: 388 RSDYLNTFEFMD 399
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>IDHP_HUMAN (P48735) Isocitrate dehydrogenase [NADP], mitochondrial precursor|
           (EC 1.1.1.42) (Oxalosuccinate decarboxylase) (IDH)
           (NADP(+)-specific ICDH) (IDP) (ICD-M)
          Length = 452

 Score =  199 bits (505), Expect = 7e-51
 Identities = 99/135 (73%), Positives = 110/135 (81%), Gaps = 1/135 (0%)
 Frame = -2

Query: 609 ACKNYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETST 430
           ACKNYD DVQSD LAQGFGSLGLMTSVL+CPDGKTIEAEAAHGTVTRH+R HQKG  TST
Sbjct: 307 ACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTST 366

Query: 429 NSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVT 250
           N IASIFAWTRGL HR KLD N  L+ FAQ LE+ CV TVESG MTKDLA  +HG S V 
Sbjct: 367 NPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKDLAGCIHGLSNVK 426

Query: 249 RSD-YLNTEEFIDAV 208
            ++ +LNT +F+D +
Sbjct: 427 LNEHFLNTTDFLDTI 441
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>IDHC_HUMAN (O75874) Isocitrate dehydrogenase [NADP] cytoplasmic (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
           ICDH) (IDP)
          Length = 414

 Score =  197 bits (502), Expect = 2e-50
 Identities = 96/132 (72%), Positives = 110/132 (83%)
 Frame = -2

Query: 609 ACKNYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETST 430
           ACKNYD DVQSD +AQG+GSLG+MTSVL+CPDGKT+EAEAAHGTVTRH+R++QKG ETST
Sbjct: 268 ACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETST 327

Query: 429 NSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVT 250
           N IASIFAWTRGLAHRAKLD+N  L  FA  LEE  + T+E+G MTKDLA  + G   V 
Sbjct: 328 NPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQ 387

Query: 249 RSDYLNTEEFID 214
           RSDYLNT EF+D
Sbjct: 388 RSDYLNTFEFMD 399
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>IDHP_MOUSE (P54071) Isocitrate dehydrogenase [NADP], mitochondrial precursor|
           (EC 1.1.1.42) (Oxalosuccinate decarboxylase) (IDH)
           (NADP(+)-specific ICDH) (IDP) (ICD-M)
          Length = 523

 Score =  183 bits (465), Expect = 3e-46
 Identities = 94/135 (69%), Positives = 105/135 (77%), Gaps = 1/135 (0%)
 Frame = -2

Query: 609 ACKNYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETST 430
           ACKNYD DVQSD LA  FGSLGLMTSVL+CPDGKTIEAEAAHGTVTRH+R HQKG  TST
Sbjct: 379 ACKNYDGDVQSDILASRFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTST 438

Query: 429 NSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVT 250
             IASIFAWTRGL HR KLD N  L+ FAQ  E+ CV TVE G MTKDLA  +HG S V 
Sbjct: 439 KGIASIFAWTRGLEHRGKLDGNQDLIRFAQTREKVCVQTVE-GAMTKDLAGCIHGLSNVK 497

Query: 249 RSD-YLNTEEFIDAV 208
            ++ +LNT +F+D +
Sbjct: 498 LNEHFLNTTDFLDTI 512
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>IDH_MYCTU (P65097) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
           ICDH) (IDP)
          Length = 409

 Score =  183 bits (464), Expect = 4e-46
 Identities = 91/135 (67%), Positives = 106/135 (78%)
 Frame = -2

Query: 609 ACKNYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETST 430
           ACKNYD DVQSD +AQG+GSLGLMTSVLM  DGKT+EAEAAHGTVTRH+R +Q G  TST
Sbjct: 271 ACKNYDGDVQSDTVAQGYGSLGLMTSVLMTADGKTVEAEAAHGTVTRHYRQYQAGKPTST 330

Query: 429 NSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVT 250
           N IASIFAWTRGL HR KLD    +++FA KLE   + TVESGKMTKDLA+L+       
Sbjct: 331 NPIASIFAWTRGLQHRGKLDGTPEVIDFAHKLESVVIATVESGKMTKDLAILIG-----P 385

Query: 249 RSDYLNTEEFIDAVA 205
             D+LN+EEF+DA+A
Sbjct: 386 EQDWLNSEEFLDAIA 400
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>IDH_MYCBO (P65098) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
           ICDH) (IDP)
          Length = 409

 Score =  183 bits (464), Expect = 4e-46
 Identities = 91/135 (67%), Positives = 106/135 (78%)
 Frame = -2

Query: 609 ACKNYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETST 430
           ACKNYD DVQSD +AQG+GSLGLMTSVLM  DGKT+EAEAAHGTVTRH+R +Q G  TST
Sbjct: 271 ACKNYDGDVQSDTVAQGYGSLGLMTSVLMTADGKTVEAEAAHGTVTRHYRQYQAGKPTST 330

Query: 429 NSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVT 250
           N IASIFAWTRGL HR KLD    +++FA KLE   + TVESGKMTKDLA+L+       
Sbjct: 331 NPIASIFAWTRGLQHRGKLDGTPEVIDFAHKLESVVIATVESGKMTKDLAILIG-----P 385

Query: 249 RSDYLNTEEFIDAVA 205
             D+LN+EEF+DA+A
Sbjct: 386 EQDWLNSEEFLDAIA 400
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>IDH1_CANTR (O13285) Isocitrate dehydrogenase [NADP], mitochondrial precursor|
           (EC 1.1.1.42) (Oxalosuccinate decarboxylase) (IDH)
           (NADP(+)-specific ICDH) (IDP) (CtIDP1)
          Length = 430

 Score =  176 bits (447), Expect = 4e-44
 Identities = 93/136 (68%), Positives = 106/136 (77%), Gaps = 1/136 (0%)
 Frame = -2

Query: 609 ACKNYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETST 430
           A KNYD DVQSD +AQGFGSLGLMTS LM PDGK  EAEAAHGTVTRH+R HQ+G ETST
Sbjct: 293 ALKNYDGDVQSDIVAQGFGSLGLMTSALMTPDGKAYEAEAAHGTVTRHYRQHQQGKETST 352

Query: 429 NSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGK-MTKDLALLVHGSSKV 253
           NSIASIFAWTRGLA R KLD+   +++FA KLE+A + TVE  + MTKDLAL +    K 
Sbjct: 353 NSIASIFAWTRGLAQRGKLDETPDVVDFASKLEQATIDTVEVDRIMTKDLALAM---GKT 409

Query: 252 TRSDYLNTEEFIDAVA 205
            RS Y+ T EF+DAVA
Sbjct: 410 DRSAYVTTTEFLDAVA 425
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>IDHC_YEAST (P41939) Isocitrate dehydrogenase [NADP] cytoplasmic (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
           ICDH) (IDP)
          Length = 412

 Score =  175 bits (443), Expect = 1e-43
 Identities = 93/135 (68%), Positives = 106/135 (78%), Gaps = 1/135 (0%)
 Frame = -2

Query: 609 ACKNYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETST 430
           A KNYD DV+SD +AQGFGSLGLMTSVL+ PDGKT E+EAAHGTVTRHFR HQ+G ETST
Sbjct: 268 AMKNYDGDVESDIVAQGFGSLGLMTSVLITPDGKTFESEAAHGTVTRHFRQHQQGKETST 327

Query: 429 NSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTV-ESGKMTKDLALLVHGSSKV 253
           NSIASIFAWTRG+  R KLD+   +++F Q LE A V TV E G MTKDLAL++    K 
Sbjct: 328 NSIASIFAWTRGIIQRGKLDNTPDVVKFGQILESATVNTVQEDGIMTKDLALIL---GKS 384

Query: 252 TRSDYLNTEEFIDAV 208
            RS Y+ TEEFIDAV
Sbjct: 385 ERSAYVTTEEFIDAV 399
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>IDHH_YEAST (P53982) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
           ICDH) (IDP)
          Length = 420

 Score =  174 bits (442), Expect = 1e-43
 Identities = 90/136 (66%), Positives = 106/136 (77%), Gaps = 1/136 (0%)
 Frame = -2

Query: 609 ACKNYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETST 430
           A KNYD DVQSD +AQGFGSLGLMTS+L+ PDGKT E+EAAHGTVTRHFR HQ+G ETST
Sbjct: 268 AMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGKTFESEAAHGTVTRHFRKHQRGEETST 327

Query: 429 NSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVE-SGKMTKDLALLVHGSSKV 253
           NSIASIFAWTR +  R KLD+   +++F   LE+A + TV+  GKMTKDLAL++    K 
Sbjct: 328 NSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEKATLDTVQVGGKMTKDLALML---GKT 384

Query: 252 TRSDYLNTEEFIDAVA 205
            RS Y+ TEEFID VA
Sbjct: 385 NRSSYVTTEEFIDEVA 400
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>IDH_SPHYA (P50215) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
           ICDH) (IDP)
          Length = 406

 Score =  174 bits (441), Expect = 2e-43
 Identities = 85/134 (63%), Positives = 104/134 (77%)
 Frame = -2

Query: 609 ACKNYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETST 430
           ACKNYD DVQSD +AQGFGSLGLMTSVL+ PDGKT+EAEAAHGTVTRH+R HQ+G  TST
Sbjct: 266 ACKNYDGDVQSDTVAQGFGSLGLMTSVLLSPDGKTVEAEAAHGTVTRHYRQHQQGKATST 325

Query: 429 NSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVT 250
           N IASIFAWT+GL+ R K DD   +++FA+ LE+ C+ TVE G MTKDLALL+       
Sbjct: 326 NPIASIFAWTQGLSFRGKFDDTPDVVKFAETLEQVCIKTVEGGAMTKDLALLIGPDQA-- 383

Query: 249 RSDYLNTEEFIDAV 208
              ++ TE+F +A+
Sbjct: 384 ---WMTTEQFFEAI 394
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>IDH2_CANTR (O13294) Isocitrate dehydrogenase [NADP] peroxisomal (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (PS-NADP-IDH)
           (CtIDP2)
          Length = 410

 Score =  173 bits (438), Expect = 4e-43
 Identities = 90/136 (66%), Positives = 104/136 (76%), Gaps = 1/136 (0%)
 Frame = -2

Query: 609 ACKNYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETST 430
           A KNYD DVQSD +AQGFGSLGLMTSVL+ PDGK  E+EAAHGTVTRH+R HQ+G ETST
Sbjct: 269 AMKNYDGDVQSDIVAQGFGSLGLMTSVLVTPDGKAFESEAAHGTVTRHYRQHQQGKETST 328

Query: 429 NSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGK-MTKDLALLVHGSSKV 253
           NSIASI+AWTRGL  R KLDD   +++FA++LE+A + TV     MTKDLAL      K 
Sbjct: 329 NSIASIYAWTRGLIQRGKLDDTPEVVKFAEELEKAVIETVSKDNIMTKDLALT---QGKT 385

Query: 252 TRSDYLNTEEFIDAVA 205
            RS Y+ TEEFID VA
Sbjct: 386 DRSSYVTTEEFIDGVA 401
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>IDHP_SCHPO (O14254) Probable isocitrate dehydrogenase [NADP], mitochondrial|
           precursor (EC 1.1.1.42) (Oxalosuccinate decarboxylase)
           (IDH) (NADP(+)-specific ICDH) (IDP)
          Length = 418

 Score =  166 bits (421), Expect = 4e-41
 Identities = 86/137 (62%), Positives = 104/137 (75%)
 Frame = -2

Query: 609 ACKNYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETST 430
           ACKNYD DV SD +AQ +GSLGLMTSVL+ P+G+T E+EAAHGTV RH+  + KG +TST
Sbjct: 278 ACKNYDGDVMSDVVAQAYGSLGLMTSVLIHPNGRTFESEAAHGTVQRHYMQYLKGKKTST 337

Query: 429 NSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVT 250
           NSIASIFAWTRGLAHR +LD N RL++FA  LE ACV  VE G MTKDL LL       +
Sbjct: 338 NSIASIFAWTRGLAHRGRLDGNERLVKFANALEHACVRCVEKGIMTKDLYLL-----SKS 392

Query: 249 RSDYLNTEEFIDAVAAE 199
            + Y++T EF+DAV +E
Sbjct: 393 PNGYVDTFEFLDAVKSE 409
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>IDHP_YEAST (P21954) Isocitrate dehydrogenase [NADP], mitochondrial precursor|
           (EC 1.1.1.42) (Oxalosuccinate decarboxylase) (IDH)
           (NADP(+)-specific ICDH) (IDP)
          Length = 428

 Score =  165 bits (418), Expect = 8e-41
 Identities = 88/135 (65%), Positives = 103/135 (76%), Gaps = 1/135 (0%)
 Frame = -2

Query: 609 ACKNYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETST 430
           A KNYD DVQSD +AQGFGSLGLMTS+L+ PDGKT E+EAAHGTVTRH+R +QKG ETST
Sbjct: 285 ALKNYDGDVQSDIVAQGFGSLGLMTSILVTPDGKTFESEAAHGTVTRHYRKYQKGEETST 344

Query: 429 NSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTV-ESGKMTKDLALLVHGSSKV 253
           NSIASIFAW+RGL  R +LD+   L +FA  LE A + TV + G MTKDLAL    +   
Sbjct: 345 NSIASIFAWSRGLLKRGELDNTPALCKFANILESATLNTVQQDGIMTKDLALACGNNE-- 402

Query: 252 TRSDYLNTEEFIDAV 208
            RS Y+ TEEF+DAV
Sbjct: 403 -RSAYVTTEEFLDAV 416
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>IDHP_ASPNG (P79089) Isocitrate dehydrogenase [NADP], mitochondrial precursor|
           (EC 1.1.1.42) (Oxalosuccinate decarboxylase) (IDH)
           (NADP(+)-specific ICDH) (IDP)
          Length = 498

 Score =  155 bits (392), Expect = 9e-38
 Identities = 81/135 (60%), Positives = 98/135 (72%), Gaps = 1/135 (0%)
 Frame = -2

Query: 609 ACKNYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETST 430
           A KNYD DVQSD +AQGFGSLGLMTS L+ P G+  E+EAAHGTVTRH+R HQKG ETST
Sbjct: 355 ALKNYDGDVQSDIVAQGFGSLGLMTSTLVTPTGEAFESEAAHGTVTRHYREHQKGRETST 414

Query: 429 NSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTV-ESGKMTKDLALLVHGSSKV 253
           N IASIFAWTRGL  R KLD+   ++ FA++LE AC+  V + G MTKDLAL      + 
Sbjct: 415 NPIASIFAWTRGLIQRGKLDETPDVVTFAEELERACIEVVNDEGIMTKDLAL---ACGRK 471

Query: 252 TRSDYLNTEEFIDAV 208
            R  ++ T E++ AV
Sbjct: 472 EREAWVTTREYMAAV 486
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>LEU3_CAMJR (Q5HS77) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 358

 Score = 38.5 bits (88), Expect = 0.015
 Identities = 39/134 (29%), Positives = 53/134 (39%), Gaps = 1/134 (0%)
 Frame = -2

Query: 606 CKNYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTI-EAEAAHGTVTRHFRVHQKGGETST 430
           C N   D+ SD LA   GSLGL++S  +   G  + E          H  +         
Sbjct: 239 CSNLFGDILSDELAAINGSLGLLSSASLNDKGFGLYEPAGGSAPDIAHLNI--------A 290

Query: 429 NSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVT 250
           N IA I +    L +  K +      + AQ +E A    +  GKMTKDL           
Sbjct: 291 NPIAQILSAALMLKYSFKEE------QAAQDIENAISLALAQGKMTKDL----------N 334

Query: 249 RSDYLNTEEFIDAV 208
              YLNT+E  D +
Sbjct: 335 AKSYLNTDEMGDCI 348
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>LEU3_CAMJE (Q9PLW0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 358

 Score = 38.5 bits (88), Expect = 0.015
 Identities = 39/134 (29%), Positives = 53/134 (39%), Gaps = 1/134 (0%)
 Frame = -2

Query: 606 CKNYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTI-EAEAAHGTVTRHFRVHQKGGETST 430
           C N   D+ SD LA   GSLGL++S  +   G  + E          H  +         
Sbjct: 239 CSNLFGDILSDELAAINGSLGLLSSASLNDKGFGLYEPAGGSAPDIAHLNI--------A 290

Query: 429 NSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVT 250
           N IA I +    L +  K +      + AQ +E A    +  GKMTKDL           
Sbjct: 291 NPIAQILSAALMLKYSFKEE------QAAQDIENAISLALAQGKMTKDL----------N 334

Query: 249 RSDYLNTEEFIDAV 208
              YLNT+E  D +
Sbjct: 335 AKSYLNTDEMGDCI 348
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>IDH3A_RAT (Q99NA5) Isocitrate dehydrogenase [NAD] subunit alpha,|
           mitochondrial precursor (EC 1.1.1.41) (Isocitric
           dehydrogenase) (NAD(+)-specific ICDH)
          Length = 366

 Score = 37.7 bits (86), Expect = 0.026
 Identities = 41/127 (32%), Positives = 56/127 (44%), Gaps = 1/127 (0%)
 Frame = -2

Query: 600 NYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 421
           N   D+ SD  A   G LG+  S  +  +G  I  E+ HGT           G+   N  
Sbjct: 253 NLYGDILSDLCAGLIGGLGVTQSGNIGANGVAI-FESVHGTAP------DIAGKDMANPT 305

Query: 420 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGK-MTKDLALLVHGSSKVTRS 244
           A + +    L H         L + A K+E AC  T++ GK +TKDL     G+SK   S
Sbjct: 306 ALLLSAVMMLRHMG-------LFDHAAKIEAACFATIKDGKSLTKDLG----GNSKC--S 352

Query: 243 DYLNTEE 223
           D+  TEE
Sbjct: 353 DF--TEE 357
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>IDH3A_BOVIN (P41563) Isocitrate dehydrogenase [NAD] subunit alpha,|
           mitochondrial precursor (EC 1.1.1.41) (Isocitric
           dehydrogenase) (NAD(+)-specific ICDH) (Isocitrate
           dehydrogenase subunits 3/4)
          Length = 366

 Score = 37.7 bits (86), Expect = 0.026
 Identities = 41/127 (32%), Positives = 56/127 (44%), Gaps = 1/127 (0%)
 Frame = -2

Query: 600 NYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 421
           N   D+ SD  A   G LG+  S  +  +G  I  E+ HGT           G+   N  
Sbjct: 253 NLYGDILSDLCAGLIGGLGVTPSGNIGANGVAI-FESVHGTAP------DIAGKDMANPT 305

Query: 420 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGK-MTKDLALLVHGSSKVTRS 244
           A + +    L H         L + A K+E AC  T++ GK +TKDL     G+SK   S
Sbjct: 306 ALLLSAVMMLRHMG-------LFDHAAKIETACFATIKDGKSLTKDLG----GNSKC--S 352

Query: 243 DYLNTEE 223
           D+  TEE
Sbjct: 353 DF--TEE 357
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>IDH3A_MOUSE (Q9D6R2) Isocitrate dehydrogenase [NAD] subunit alpha,|
           mitochondrial precursor (EC 1.1.1.41) (Isocitric
           dehydrogenase) (NAD(+)-specific ICDH)
          Length = 366

 Score = 37.0 bits (84), Expect = 0.045
 Identities = 33/107 (30%), Positives = 46/107 (42%), Gaps = 1/107 (0%)
 Frame = -2

Query: 600 NYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 421
           N   D+ SD  A   G LG+  S  +  +G  I  E+ HGT           G+   N  
Sbjct: 253 NLYGDILSDLCAGLIGGLGVTPSGNIGANGVAI-FESVHGTAP------DIAGKDMANPT 305

Query: 420 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGK-MTKDL 283
           A + +    L H         L + A K+E AC  T++ GK +TKDL
Sbjct: 306 ALLLSAVMMLRHMG-------LFDHAAKIEAACFATIKDGKSLTKDL 345
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>LEU3_NEIMB (Q9JZI9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 356

 Score = 35.0 bits (79), Expect = 0.17
 Identities = 31/109 (28%), Positives = 51/109 (46%)
 Frame = -2

Query: 609 ACKNYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETST 430
           A  N   D+ SD  +   GS+G++ S  +  +GK +  E +HG+           G+   
Sbjct: 240 ATGNIFGDILSDEASMLTGSIGMLPSASLDENGKGL-YEPSHGSAP------DIAGQNKA 292

Query: 429 NSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 283
           N +A+I +    L  R  L+D AR    AQ++E A    ++ G  T D+
Sbjct: 293 NPLATILSLAMLL--RYSLNDEAR----AQQVENAVQKVLQQGLRTSDI 335
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>LEU3_SHEON (Q8E9N3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 364

 Score = 33.9 bits (76), Expect = 0.38
 Identities = 32/108 (29%), Positives = 46/108 (42%)
 Frame = -2

Query: 606 CKNYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 427
           C N   D+ SD +A   GS+GL++S  M   G  +  E A G+           G+   N
Sbjct: 243 CSNLFGDILSDEIAMLTGSMGLLSSASMNSTGFGL-FEPAGGSAP------DIAGKGIAN 295

Query: 426 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 283
            IA I +    L H  K +      E A  +E A    + SG +T +L
Sbjct: 296 PIAQILSAALMLRHSLKQE------EAASAIERAVTKALNSGYLTGEL 337
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>LEU3_NEIMA (Q9JU79) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 356

 Score = 33.9 bits (76), Expect = 0.38
 Identities = 30/109 (27%), Positives = 51/109 (46%)
 Frame = -2

Query: 609 ACKNYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETST 430
           A  N   D+ SD  +   GS+G++ S  +  +GK +  E +HG+           G+   
Sbjct: 240 ATGNIFGDILSDEASMLTGSIGMLPSASLDENGKGL-YEPSHGSAP------DIAGQNKA 292

Query: 429 NSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 283
           N +A++ +    L  R  L+D AR    AQ++E A    ++ G  T D+
Sbjct: 293 NPLATVLSLAMLL--RYSLNDEAR----AQQVENAVQKVLQQGLRTGDI 335
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>LEU3_BUCUE (Q9EVH5) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 364

 Score = 33.5 bits (75), Expect = 0.50
 Identities = 34/134 (25%), Positives = 55/134 (41%)
 Frame = -2

Query: 606 CKNYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 427
           C N   D+ SD  A   GS+G++ S  +      +  E A G+           G+   N
Sbjct: 245 CSNLFGDIVSDECAAITGSIGMLPSASLNEKNFGL-YEPAGGSAP------DIAGKNIAN 297

Query: 426 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTR 247
            IA I + +  + H         L + A K++E+ V  ++ G  T D++   H       
Sbjct: 298 PIAQILSVSMLVRH------GMNLKKIADKIDESVVSVLKQGYRTADISNNSH------- 344

Query: 246 SDYLNTEEFIDAVA 205
            +YL T E  D +A
Sbjct: 345 -NYLKTSEMGDIIA 357
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>LEU3_BUCUA (Q9EVG6) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 33.1 bits (74), Expect = 0.65
 Identities = 32/135 (23%), Positives = 58/135 (42%)
 Frame = -2

Query: 606 CKNYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 427
           C N   D+ SD  A   GS+G++ S  +  + K    E A G+           G+   N
Sbjct: 245 CSNLFGDIISDECAMITGSIGMLPSASL-NEKKFGLYEPAGGSAP------DIEGKNIAN 297

Query: 426 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTR 247
            IA I + +  + +      +  L + A K++++ +  ++ G  T D++           
Sbjct: 298 PIAQILSLSMLVRY------SMNLKKIADKIDQSVISVLKKGYRTADIS---------NN 342

Query: 246 SDYLNTEEFIDAVAA 202
           +DYL T E  D +A+
Sbjct: 343 NDYLKTNEMGDVIAS 357
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>LEU3_PHOPR (Q6LV25) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 362

 Score = 33.1 bits (74), Expect = 0.65
 Identities = 37/135 (27%), Positives = 59/135 (43%)
 Frame = -2

Query: 606 CKNYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 427
           C N   D+ SD  A   GS+G++ S  +  + K    E A G+           G+   N
Sbjct: 245 CSNIFGDIISDECAMITGSMGMLPSASLNQE-KFGMYEPAGGSAP------DIAGKNIAN 297

Query: 426 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTR 247
            +A I +    L  R  LD+     + A+ +E+A    +E+G++T DLA          +
Sbjct: 298 PVAQILS--AALMLRYSLDEE----KAARAIEQAVSQALEAGELTADLA---------GK 342

Query: 246 SDYLNTEEFIDAVAA 202
              L+T E  D +AA
Sbjct: 343 GAALSTSEMGDKIAA 357
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>LEU3_NEIG1 (Q5F8T6) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 356

 Score = 33.1 bits (74), Expect = 0.65
 Identities = 30/109 (27%), Positives = 51/109 (46%)
 Frame = -2

Query: 609 ACKNYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETST 430
           A  N   D+ SD  +   GS+G++ S  +  +GK +  E +HG+           G+   
Sbjct: 240 ATGNIFGDILSDEASMLTGSIGMLPSASLDENGKGL-YEPSHGSAP------DIAGQNKA 292

Query: 429 NSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 283
           N +A+I +    L  R  L+D AR    AQ++E +    ++ G  T D+
Sbjct: 293 NPLATILSLAMLL--RYSLNDEAR----AQQVENSVQKVLQQGLRTGDI 335
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>LEU3_LEPIN (P24015) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 358

 Score = 32.7 bits (73), Expect = 0.85
 Identities = 28/109 (25%), Positives = 49/109 (44%)
 Frame = -2

Query: 606 CKNYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 427
           C+N   D+ SD  +   GS+G++ S  +   G  +  E + G+           G+   N
Sbjct: 243 CENMFGDILSDEASIITGSIGMLPSASLSESGFGLY-EPSGGSAP------DIAGKGVAN 295

Query: 426 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLA 280
            IA + +    L +   +++ A       K+E A   T+ SGK T+D+A
Sbjct: 296 PIAQVLSAALMLRYSFSMEEEAN------KIETAVRKTIASGKRTRDIA 338
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>LEU3_LEPIC (Q72RH7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 358

 Score = 32.7 bits (73), Expect = 0.85
 Identities = 28/109 (25%), Positives = 49/109 (44%)
 Frame = -2

Query: 606 CKNYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 427
           C+N   D+ SD  +   GS+G++ S  +   G  +  E + G+           G+   N
Sbjct: 243 CENMFGDILSDEASIITGSIGMLPSASLSESGFGLY-EPSGGSAP------DIAGKGVAN 295

Query: 426 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLA 280
            IA + +    L +   +++ A       K+E A   T+ SGK T+D+A
Sbjct: 296 PIAQVLSAALMLRYSFSMEEEAN------KIETAVRKTIASGKRTRDIA 338
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>LEU3_DESPS (Q6ANR1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 357

 Score = 32.3 bits (72), Expect = 1.1
 Identities = 38/135 (28%), Positives = 54/135 (40%)
 Frame = -2

Query: 606 CKNYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 427
           C N   D+ SD  A   GS+GL+ S  +  +   +  E A G+           G+   N
Sbjct: 242 CGNMFGDIISDEAAMLTGSMGLLASASLNTENFGL-FEPAGGSAP------DIAGQGIAN 294

Query: 426 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTR 247
            IA I +    L +           E A  +E A   T++ G  T D+A        V R
Sbjct: 295 PIAEILSAAMMLRYSLGYG------EAADAIEAAVEKTLDRGICTADIA--------VDR 340

Query: 246 SDYLNTEEFIDAVAA 202
           S  +NT E  DA+ A
Sbjct: 341 SQAVNTAEMGDAIVA 355
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>LEU3_ZYMMO (Q5NPQ9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 349

 Score = 32.0 bits (71), Expect = 1.4
 Identities = 28/106 (26%), Positives = 46/106 (43%)
 Frame = -2

Query: 600 NYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 421
           N   D+ SD  +   GS+GL+ S  +  +GK +  E  HG+           G    N +
Sbjct: 239 NLFGDILSDLASACVGSIGLLPSASLNSEGKGL-YEPIHGSAP------DIAGLGKANPL 291

Query: 420 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 283
           A+I +    L +  K + +      A ++E+A    +E G  T DL
Sbjct: 292 ATILSGAMMLRYSLKREAD------ADRIEKAVSTALEKGARTADL 331
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>ATG16_XENTR (Q5I0B9) Autophagy-related protein 16 (APG16-like 1)|
          Length = 537

 Score = 32.0 bits (71), Expect = 1.4
 Identities = 24/83 (28%), Positives = 36/83 (43%), Gaps = 7/83 (8%)
 Frame = -2

Query: 585 VQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTV-------TRHFRVHQKGGETSTN 427
           VQ  F A GF      T V+  PDG  + A +A GT+        +  R+  K   +S N
Sbjct: 452 VQQTFSAPGFKCGSDWTRVIFSPDGSYVSAGSAEGTLYFWNVLTGKVERMFSKQHSSSIN 511

Query: 426 SIASIFAWTRGLAHRAKLDDNAR 358
           ++    AW+    H   +D  +R
Sbjct: 512 AV----AWSPSGTHVVSVDKGSR 530
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>LEU3_PASMU (Q9CJN6) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 359

 Score = 32.0 bits (71), Expect = 1.4
 Identities = 37/134 (27%), Positives = 53/134 (39%)
 Frame = -2

Query: 606 CKNYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 427
           C N   D+ SD  A   GS+G++ S  +   G  +  E A G+           G+   N
Sbjct: 244 CSNIFGDIISDECAMITGSMGMLPSASLNEKGFGL-YEPAGGSAP------DIAGKGIAN 296

Query: 426 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTR 247
            IA I +    L H   L+D A  +E A K        +  G  T DLA           
Sbjct: 297 PIAQILSAAMMLRHSFNLNDAATAIENAVK------NVLAEGHRTADLA---------DE 341

Query: 246 SDYLNTEEFIDAVA 205
           S  L+T++  D +A
Sbjct: 342 SQPLSTKQMGDLIA 355
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>LEU3_BACSU (P05645) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 365

 Score = 32.0 bits (71), Expect = 1.4
 Identities = 38/135 (28%), Positives = 58/135 (42%)
 Frame = -2

Query: 603 KNYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNS 424
           +N   D+ SD  +   GSLG++ S  +   G  +  E  HG+           G+   N 
Sbjct: 243 ENMFGDILSDEASMLTGSLGMLPSASLSSSGLHL-FEPVHGSAP------DIAGKGMANP 295

Query: 423 IASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTRS 244
            A+I      L+    L  +  L E A+ +E+A    + SGK T+DLA      S+   S
Sbjct: 296 FAAI------LSAAMLLRTSFGLEEEAKAVEDAVNKVLASGKRTRDLA-----RSEEFSS 344

Query: 243 DYLNTEEFIDAVAAE 199
               TEE   A+ +E
Sbjct: 345 TQAITEEVKAAIMSE 359
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>LEU3_BACLD (Q65GI9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 370

 Score = 32.0 bits (71), Expect = 1.4
 Identities = 31/108 (28%), Positives = 47/108 (43%)
 Frame = -2

Query: 603 KNYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNS 424
           +N   D+ SD  +   GSLG++ S  +   G  +  E  HG+           G+   N 
Sbjct: 243 ENMFGDILSDEASMLTGSLGMLPSASLSSSGLHLY-EPVHGSAP------DIAGQNIANP 295

Query: 423 IASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLA 280
           +A+I      L+    L  +  L   AQ +E A    + +GK TKDLA
Sbjct: 296 LAAI------LSAAMMLRTSFGLEAEAQAVEHAVDQVLRAGKRTKDLA 337
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>LEU3_SHIDS (Q32K21) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 31.6 bits (70), Expect = 1.9
 Identities = 37/134 (27%), Positives = 55/134 (41%)
 Frame = -2

Query: 606 CKNYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 427
           C N   D+ SD  A   GS+G++ S  +   G  +  E A G+           G+   N
Sbjct: 245 CSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YEPAGGSAP------DIAGKNIAN 297

Query: 426 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTR 247
            IA I +    L +    DD       A  +E A    +E G  T+DLA    G++ V  
Sbjct: 298 PIAQILSLALLLRYSLDADD------AASAIERAINRALEEGIRTRDLA---RGAAAV-- 346

Query: 246 SDYLNTEEFIDAVA 205
               +T+E  D +A
Sbjct: 347 ----STDEMGDIIA 356
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>LEU3_SALTY (P37412) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 31.2 bits (69), Expect = 2.5
 Identities = 39/134 (29%), Positives = 57/134 (42%)
 Frame = -2

Query: 606 CKNYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 427
           C N   D+ SD  A   GS+G++ S  +   G  +  E A G+           G+   N
Sbjct: 245 CSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YEPAGGSAP------DIAGKNIAN 297

Query: 426 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTR 247
            IA I   +  L  R  LD N    + A  +E+A    +E G  T DLA    G++ V  
Sbjct: 298 PIAQIL--SLALLLRYSLDAN----DAATAIEQAINRALEEGVRTGDLA---RGAAAV-- 346

Query: 246 SDYLNTEEFIDAVA 205
               +T+E  D +A
Sbjct: 347 ----STDEMGDIIA 356
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>LEU3_SALPA (Q5PDG2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 31.2 bits (69), Expect = 2.5
 Identities = 39/134 (29%), Positives = 57/134 (42%)
 Frame = -2

Query: 606 CKNYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 427
           C N   D+ SD  A   GS+G++ S  +   G  +  E A G+           G+   N
Sbjct: 245 CSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YEPAGGSAP------DIAGKNIAN 297

Query: 426 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTR 247
            IA I   +  L  R  LD N    + A  +E+A    +E G  T DLA    G++ V  
Sbjct: 298 PIAQIL--SLALLLRYSLDAN----DAATAIEQAINRALEEGVRTGDLA---RGAAAV-- 346

Query: 246 SDYLNTEEFIDAVA 205
               +T+E  D +A
Sbjct: 347 ----STDEMGDIIA 356
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>LEU3_SALCH (Q57TE7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 31.2 bits (69), Expect = 2.5
 Identities = 39/134 (29%), Positives = 57/134 (42%)
 Frame = -2

Query: 606 CKNYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 427
           C N   D+ SD  A   GS+G++ S  +   G  +  E A G+           G+   N
Sbjct: 245 CSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YEPAGGSAP------DIAGKNIAN 297

Query: 426 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTR 247
            IA I   +  L  R  LD N    + A  +E+A    +E G  T DLA    G++ V  
Sbjct: 298 PIAQIL--SLALLLRYSLDAN----DAATAIEQAINRALEEGVRTGDLA---RGAAAV-- 346

Query: 246 SDYLNTEEFIDAVA 205
               +T+E  D +A
Sbjct: 347 ----STDEMGDIIA 356
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>LEU3_CAUCR (Q9ABN3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 350

 Score = 31.2 bits (69), Expect = 2.5
 Identities = 29/106 (27%), Positives = 43/106 (40%)
 Frame = -2

Query: 600 NYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 421
           N   D+ SD  A   GSLG++ S  +   GK    E  HG+           G+   N +
Sbjct: 240 NLFGDILSDAAAMLTGSLGMLPSAALGAPGKPGLYEPIHGSAP------DIAGKGLANPL 293

Query: 420 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 283
           A+I ++   L    K        E A  L  A    +++G  T+DL
Sbjct: 294 AAILSFEMALRWSLK------QTEAADALLAAVKAALDNGARTRDL 333
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>LEU3_COLP3 (Q47WG3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 362

 Score = 31.2 bits (69), Expect = 2.5
 Identities = 32/108 (29%), Positives = 47/108 (43%)
 Frame = -2

Query: 606 CKNYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 427
           C N   D+ SD  A   GS+GL+ S  +  DG  +  E A G+           G    N
Sbjct: 242 CPNLFGDILSDICAMITGSMGLLPSASLNSDGFGM-YEPAGGSAP------DIAGLGVAN 294

Query: 426 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 283
            IA I   +  L  R  L+  A     A+ +E+A    +++G +T DL
Sbjct: 295 PIAQIL--SAALMLRYSLNQGAA----AKAIEDAVSNALDNGVLTADL 336
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>INHBA_SHEEP (P43032) Inhibin beta A chain precursor (Activin beta-A chain)|
          Length = 425

 Score = 30.4 bits (67), Expect = 4.2
 Identities = 24/97 (24%), Positives = 49/97 (50%), Gaps = 1/97 (1%)
 Frame = -2

Query: 498 AEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTR-GLAHRAKLDDNARLLEFAQKLEEAC 322
           AE+     T HF + Q+G + S    A I+ + +   A+R +     RL +  + L+   
Sbjct: 127 AESGTARKTLHFEISQEGSDLSVVERAEIWLFLKVPKANRTRSKVTIRLFQQQKHLQ--- 183

Query: 321 VGTVESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDA 211
            G++++G+  +++ L      K  +S+ L +E+ +DA
Sbjct: 184 -GSLDAGEEAEEVGL------KGEKSEMLISEKVVDA 213
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>LEU3_YERPE (Q8ZIG9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 30.4 bits (67), Expect = 4.2
 Identities = 32/109 (29%), Positives = 43/109 (39%)
 Frame = -2

Query: 606 CKNYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 427
           C N   D+ SD  A   GS+G++ S  +   G  +  E A G+           G+   N
Sbjct: 245 CSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YEPAGGSAP------DIAGKNIAN 297

Query: 426 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLA 280
            IA I + T  L      DD       A  +E A    +E G  T DLA
Sbjct: 298 PIAQILSLTLLLRFSLGKDD------AADAIERAINQALEQGYRTADLA 340
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>LEU3_BUCUS (Q9EVI4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 30.4 bits (67), Expect = 4.2
 Identities = 32/135 (23%), Positives = 56/135 (41%)
 Frame = -2

Query: 606 CKNYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 427
           C N   D+ SD  A   GS+G++ S  +  + K    E A G+           G+   N
Sbjct: 245 CSNLFGDIISDECAMITGSIGMLPSASL-NEKKFGLYEPAGGSAP------DIEGKNIAN 297

Query: 426 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTR 247
            IA I + +  + +      +  L   A K++++ +  ++ G  T D++           
Sbjct: 298 PIAQILSVSMLVRY------SMNLKTIADKIDQSVISVLKKGYRTADIS---------NN 342

Query: 246 SDYLNTEEFIDAVAA 202
           S YL T E  D +A+
Sbjct: 343 SHYLKTNEMGDVIAS 357
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>LEU3_VIBPA (Q87SS8) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 30.0 bits (66), Expect = 5.5
 Identities = 31/109 (28%), Positives = 47/109 (43%)
 Frame = -2

Query: 606 CKNYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 427
           C N   D+ SD  A   GS+G++ S  +  + K    E A G+           G+   N
Sbjct: 246 CSNIFGDIISDECAMITGSMGMLPSASL-NESKFGLYEPAGGSAP------DIAGKNIAN 298

Query: 426 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLA 280
            +A I   +  L  R  L + A     AQ +E A    + +G++T DLA
Sbjct: 299 PVAQIL--SAALMLRYSLGEEAA----AQDIESAVSKALSAGELTADLA 341
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>LEU3_ERWCT (Q6D0G7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 30.0 bits (66), Expect = 5.5
 Identities = 35/134 (26%), Positives = 53/134 (39%)
 Frame = -2

Query: 606 CKNYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 427
           C N   D+ SD  A   GS+G++ S  +   G  +  E A G+           G+   N
Sbjct: 245 CSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YEPAGGSAP------DIAGKDIAN 297

Query: 426 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTR 247
            IA I +    L +    DD       A+ +E+A    +  G  T DLA         + 
Sbjct: 298 PIAQILSLALLLRYSLGADD------AAEAIEKAVNTALAEGYRTADLA---------SA 342

Query: 246 SDYLNTEEFIDAVA 205
           S+ + T E  D +A
Sbjct: 343 SNAIGTSEMGDVIA 356
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>Y1185_METJA (Q58585) Hypothetical protein MJ1185|
          Length = 622

 Score = 30.0 bits (66), Expect = 5.5
 Identities = 22/62 (35%), Positives = 34/62 (54%)
 Frame = -3

Query: 518 LMVKQSKPKLPMAQSLVISVFTRKVVKPAQTALLPSLLGQEDLHTGQS*TTTLDFLNLHR 339
           L+V+  K +LP+ ++L I  F RK +KP    L+  LLG ED+          D +NL+R
Sbjct: 504 LVVESIKLELPI-ENLGICRFHRKWLKPVLKELVKELLGIEDI--------VEDSINLYR 554

Query: 338 NL 333
            +
Sbjct: 555 EI 556
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>LEU3_THEMA (Q9WZ26) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 354

 Score = 30.0 bits (66), Expect = 5.5
 Identities = 32/107 (29%), Positives = 45/107 (42%)
 Frame = -2

Query: 600 NYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 421
           N   D+ SD  A   GSLGL+ S      G     E A G+           G+   N I
Sbjct: 239 NMFGDILSDESAALPGSLGLLPSASF---GDKNLYEPAGGSAP------DIAGKNIANPI 289

Query: 420 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLA 280
           A I +    L H      +  ++E A+K+E A    +E G  T+D+A
Sbjct: 290 AQILSLAMMLEH------SFGMVEEARKIERAVELVIEEGYRTRDIA 330
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>LEU3_BUCUO (Q9EVI1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 364

 Score = 30.0 bits (66), Expect = 5.5
 Identities = 32/134 (23%), Positives = 56/134 (41%)
 Frame = -2

Query: 606 CKNYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 427
           C N   D+ SD  A   GS+G++ S  +  + K    E A G+           G+   N
Sbjct: 246 CPNLFGDIISDECAIITGSIGMLPSASL-NEKKFGLYEPAGGSAP------DIAGKNIAN 298

Query: 426 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTR 247
            IA I + +  + +   L D       A K++++ +  ++ G  T D++           
Sbjct: 299 PIAQILSLSMLVRYGMNLKD------IADKIDKSVLSVLKKGYRTADIS---------NN 343

Query: 246 SDYLNTEEFIDAVA 205
           ++YL T E  D +A
Sbjct: 344 NNYLKTNEMGDVIA 357
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>LEU3_SHIFL (Q83SP1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 362

 Score = 30.0 bits (66), Expect = 5.5
 Identities = 37/134 (27%), Positives = 54/134 (40%)
 Frame = -2

Query: 606 CKNYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 427
           C N   D+ SD  A   GS+G++ S  +   G  +  E A G+           G+   N
Sbjct: 244 CSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YEPAGGSAP------DIAGKNIAN 296

Query: 426 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTR 247
            IA I +    L +    DD       A  +E A    +E G  T DLA    G++ V  
Sbjct: 297 PIAQILSLALLLRYSLDADD------AASAIERAINRALEEGIRTGDLA---RGAAAV-- 345

Query: 246 SDYLNTEEFIDAVA 205
               +T+E  D +A
Sbjct: 346 ----STDEMGDIIA 355
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>LEU3_ECOL6 (Q8FL76) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 362

 Score = 30.0 bits (66), Expect = 5.5
 Identities = 37/134 (27%), Positives = 54/134 (40%)
 Frame = -2

Query: 606 CKNYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 427
           C N   D+ SD  A   GS+G++ S  +   G  +  E A G+           G+   N
Sbjct: 244 CSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YEPAGGSAP------DIAGKNIAN 296

Query: 426 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTR 247
            IA I +    L +    DD       A  +E A    +E G  T DLA    G++ V  
Sbjct: 297 PIAQILSLALLLRYSLDADD------AASAIERAINRALEEGIRTGDLA---RGAAAV-- 345

Query: 246 SDYLNTEEFIDAVA 205
               +T+E  D +A
Sbjct: 346 ----STDEMGDIIA 355
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>LEU3_ECO57 (Q8X9Z9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 362

 Score = 30.0 bits (66), Expect = 5.5
 Identities = 37/134 (27%), Positives = 54/134 (40%)
 Frame = -2

Query: 606 CKNYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 427
           C N   D+ SD  A   GS+G++ S  +   G  +  E A G+           G+   N
Sbjct: 244 CSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YEPAGGSAP------DIAGKNIAN 296

Query: 426 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTR 247
            IA I +    L +    DD       A  +E A    +E G  T DLA    G++ V  
Sbjct: 297 PIAQILSLALLLRYSLDADD------AASAIERAINRALEEGIRTGDLA---RGAAAV-- 345

Query: 246 SDYLNTEEFIDAVA 205
               +T+E  D +A
Sbjct: 346 ----STDEMGDIIA 355
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>LEU3_STAAW (Q8NVJ0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 348

 Score = 30.0 bits (66), Expect = 5.5
 Identities = 27/108 (25%), Positives = 45/108 (41%)
 Frame = -2

Query: 606 CKNYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 427
           C+N   D+ SD  +   GSLGL  S     DG  +           +  +H    + +  
Sbjct: 235 CENLFGDILSDEASVIPGSLGLSPSASFSNDGPRL-----------YEPIHGSAPDIAGK 283

Query: 426 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 283
           ++A+ F     LA    L ++    + A +LE+     +E G+ T DL
Sbjct: 284 NVANPFGMILSLA--MCLRESLNQPDAADELEQHIYNMIEHGQTTADL 329
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>LEU3_STAAS (Q6G7Q0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 348

 Score = 30.0 bits (66), Expect = 5.5
 Identities = 27/108 (25%), Positives = 45/108 (41%)
 Frame = -2

Query: 606 CKNYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 427
           C+N   D+ SD  +   GSLGL  S     DG  +           +  +H    + +  
Sbjct: 235 CENLFGDILSDEASVIPGSLGLSPSASFSNDGPRL-----------YEPIHGSAPDIAGK 283

Query: 426 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 283
           ++A+ F     LA    L ++    + A +LE+     +E G+ T DL
Sbjct: 284 NVANPFGMILSLA--MCLRESLNQPDAADELEQHIYNMIEHGQTTADL 329
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>LEU3_STAAN (P65101) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 348

 Score = 30.0 bits (66), Expect = 5.5
 Identities = 27/108 (25%), Positives = 45/108 (41%)
 Frame = -2

Query: 606 CKNYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 427
           C+N   D+ SD  +   GSLGL  S     DG  +           +  +H    + +  
Sbjct: 235 CENLFGDILSDEASVIPGSLGLSPSASFSNDGPRL-----------YEPIHGSAPDIAGK 283

Query: 426 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 283
           ++A+ F     LA    L ++    + A +LE+     +E G+ T DL
Sbjct: 284 NVANPFGMILSLA--MCLRESLNQPDAADELEQHIYNMIEHGQTTADL 329
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>LEU3_STAAM (P65100) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 348

 Score = 30.0 bits (66), Expect = 5.5
 Identities = 27/108 (25%), Positives = 45/108 (41%)
 Frame = -2

Query: 606 CKNYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 427
           C+N   D+ SD  +   GSLGL  S     DG  +           +  +H    + +  
Sbjct: 235 CENLFGDILSDEASVIPGSLGLSPSASFSNDGPRL-----------YEPIHGSAPDIAGK 283

Query: 426 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 283
           ++A+ F     LA    L ++    + A +LE+     +E G+ T DL
Sbjct: 284 NVANPFGMILSLA--MCLRESLNQPDAADELEQHIYNMIEHGQTTADL 329
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>LEU3_STAAC (Q5HEE3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 348

 Score = 30.0 bits (66), Expect = 5.5
 Identities = 27/108 (25%), Positives = 45/108 (41%)
 Frame = -2

Query: 606 CKNYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 427
           C+N   D+ SD  +   GSLGL  S     DG  +           +  +H    + +  
Sbjct: 235 CENLFGDILSDEASVIPGSLGLSPSASFSNDGPRL-----------YEPIHGSAPDIAGK 283

Query: 426 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 283
           ++A+ F     LA    L ++    + A +LE+     +E G+ T DL
Sbjct: 284 NVANPFGMILSLA--MCLRESLNQPDAADELEQHIYSMIEHGQTTADL 329
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>LEU3_HAEIN (P43860) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 358

 Score = 30.0 bits (66), Expect = 5.5
 Identities = 31/109 (28%), Positives = 45/109 (41%)
 Frame = -2

Query: 606 CKNYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 427
           C N   D+ SD  A   GS+G++ S  +  +G  +  E A G+           G+   N
Sbjct: 244 CSNIFGDIISDEAAMITGSMGMLPSASLNEEGFGL-YEPAGGSAP------DIAGKGIAN 296

Query: 426 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLA 280
            IA I +    L +   L+      E A  +E A    + SG  T DLA
Sbjct: 297 PIAQILSAAMMLRYSFNLN------EAADAIESAVQKVLASGHRTADLA 339
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>LEU3_VIBVY (Q7MP78) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 29.6 bits (65), Expect = 7.2
 Identities = 31/109 (28%), Positives = 47/109 (43%)
 Frame = -2

Query: 606 CKNYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 427
           C N   D+ SD  A   GS+G++ S  +  + K    E A G+           G+   N
Sbjct: 246 CSNIFGDIISDECAMITGSMGMLPSASL-NESKFGLYEPAGGSAP------DIAGKNIAN 298

Query: 426 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLA 280
            +A I   +  L  R  L + A     AQ +E A    + +G++T DLA
Sbjct: 299 PVAQIL--SAALMLRYSLGEEAA----AQDIENAVSQALAAGELTADLA 341
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>LEU3_VIBVU (Q8DEE0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 29.6 bits (65), Expect = 7.2
 Identities = 31/109 (28%), Positives = 47/109 (43%)
 Frame = -2

Query: 606 CKNYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 427
           C N   D+ SD  A   GS+G++ S  +  + K    E A G+           G+   N
Sbjct: 246 CSNIFGDIISDECAMITGSMGMLPSASL-NESKFGLYEPAGGSAP------DIAGKNIAN 298

Query: 426 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLA 280
            +A I   +  L  R  L + A     AQ +E A    + +G++T DLA
Sbjct: 299 PVAQIL--SAALMLRYSLGEEAA----AQDIENAVSQALAAGELTADLA 341
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>LEU3_VIBCH (Q9KP82) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 29.6 bits (65), Expect = 7.2
 Identities = 31/109 (28%), Positives = 47/109 (43%)
 Frame = -2

Query: 606 CKNYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 427
           C N   D+ SD  A   GS+G++ S  M  + K    E A G+           G+   N
Sbjct: 246 CSNIFGDILSDECAMITGSMGMLPSASM-NESKFGLYEPAGGSAP------DIAGKNIAN 298

Query: 426 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLA 280
            +A I   +  L  R  L + A     A+ +E A    + +G++T DLA
Sbjct: 299 PVAQIL--SAALMLRYSLGEEAA----ARDIENAVSQALAAGELTADLA 341
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>LEU3_BUCDN (O85071) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 29.6 bits (65), Expect = 7.2
 Identities = 31/134 (23%), Positives = 54/134 (40%)
 Frame = -2

Query: 606 CKNYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 427
           C N   D+ SD  A   GS+G++ S  +      +  E A G+           G+   N
Sbjct: 245 CSNLFGDIISDECAMITGSIGMLPSASLNEKNFGL-YEPAGGSAP------DIQGKNIAN 297

Query: 426 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTR 247
            IA I + +  + +   L+      + A K++ A +  ++ G  T D++           
Sbjct: 298 PIAQILSLSMLIRYSMNLN------KIANKIDNAVINVLKKGYKTMDIS---------KD 342

Query: 246 SDYLNTEEFIDAVA 205
            +YL T E  D +A
Sbjct: 343 QNYLKTNEMGDVIA 356
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>SYNJ1_BOVIN (O18964) Synaptojanin-1 (EC 3.1.3.36) (Synaptic|
           inositol-1,4,5-trisphosphate 5-phosphatase 1) (p150)
           (Fragment)
          Length = 1324

 Score = 29.6 bits (65), Expect = 7.2
 Identities = 28/88 (31%), Positives = 39/88 (44%), Gaps = 12/88 (13%)
 Frame = -2

Query: 477 VTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLE-------FAQKLEEA-- 325
           VTR   V +     + +SI+ I+A T  L  +AKL D AR +        F    +EA  
Sbjct: 418 VTRFQEVFRSMWSVNGDSISKIYAGTGALEGKAKLKDGARSVSRTIQNNFFDSSKQEAID 477

Query: 324 ---CVGTVESGKMTKDLALLVHGSSKVT 250
                 T+ S    K  ALL  GS +V+
Sbjct: 478 VLLLGNTLNSDLADKARALLTTGSLRVS 505
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>LEU3_GEOSL (Q748X2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 362

 Score = 29.6 bits (65), Expect = 7.2
 Identities = 34/135 (25%), Positives = 56/135 (41%)
 Frame = -2

Query: 606 CKNYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 427
           C+N   D+ SD  A   GSLG++ S  +  +G     E + G+           G+   N
Sbjct: 245 CENMFGDILSDEAAMLTGSLGMLPSASLA-EGTFGMYEPSGGSAP------DIAGQGIAN 297

Query: 426 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTR 247
            IA I      L+    L  +  +++ A  ++ A    ++ G  T+D+     G   V  
Sbjct: 298 PIAQI------LSMGMMLKFSFGMVDAADAIDNAVATVLDQGFRTRDIYQQKDGEKLV-- 349

Query: 246 SDYLNTEEFIDAVAA 202
               NT+E  DA+ A
Sbjct: 350 ----NTKEMGDAIIA 360
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>TPM1_SCHMA (P42637) Tropomyosin 1 (TMI) (Polypeptide 49)|
          Length = 284

 Score = 29.3 bits (64), Expect = 9.4
 Identities = 24/80 (30%), Positives = 39/80 (48%), Gaps = 4/80 (5%)
 Frame = -2

Query: 504 IEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDD----NARLLEFAQK 337
           I+ + A  T+       ++  + +TN+ A + A TR +  R   +D    ++RL E   K
Sbjct: 55  IDCDEAQETLQEQMNKLEETDKRATNAEAEVAAMTRRI--RLLEEDLEVSSSRLTETLTK 112

Query: 336 LEEACVGTVESGKMTKDLAL 277
           LEEA     ES +  KDL +
Sbjct: 113 LEEASKTAEESERGRKDLEI 132
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>FST_BRARE (Q9YHV4) Follistatin precursor (FS) (Activin-binding protein)|
          Length = 322

 Score = 29.3 bits (64), Expect = 9.4
 Identities = 15/34 (44%), Positives = 16/34 (47%)
 Frame = +1

Query: 385 VCKSSCPSKDGSNAVCAGFTTFLVNTEMTSDCAM 486
           VC  SCP      AVCA       NT   S+CAM
Sbjct: 272 VCAESCPESRSEEAVCAS-----DNTTYPSECAM 300
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>LEU3_PHOLL (Q7N128) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 29.3 bits (64), Expect = 9.4
 Identities = 35/126 (27%), Positives = 52/126 (41%)
 Frame = -2

Query: 606 CKNYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 427
           C N   D+ SD  A   GS+G++ S  +   G  +  E A G+           G+   N
Sbjct: 245 CSNIFGDILSDECAMITGSMGMLPSASLNEKGFGL-YEPAGGSAP------DIAGKGIAN 297

Query: 426 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTR 247
            IA I   +  L  R  L  N    + A  +E+A    +E G  T DLA    G+ K   
Sbjct: 298 PIAQIL--SAALLLRYSLGHN----DAANAIEQAVNYALEQGYRTTDLA----GNGKAIS 347

Query: 246 SDYLNT 229
           +D + +
Sbjct: 348 TDEMGS 353
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>LEU3_BUCUM (Q9EVG9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 365

 Score = 29.3 bits (64), Expect = 9.4
 Identities = 31/134 (23%), Positives = 56/134 (41%)
 Frame = -2

Query: 606 CKNYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 427
           C N   D+ SD  A   GS+G++ S  +  + K    E A G+           G+   N
Sbjct: 247 CSNLFGDIVSDECAIITGSIGMLPSASL-NEKKFGLYEPAGGSAP------DIEGKNIAN 299

Query: 426 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTR 247
            IA I + +  + +         L + A K++++ +  ++ G  T D++           
Sbjct: 300 PIAQILSVSMLVRY------GMNLKKIADKIDQSVISVLKKGYRTADIS---------NN 344

Query: 246 SDYLNTEEFIDAVA 205
           ++YL T E  D +A
Sbjct: 345 NNYLKTNEMGDVIA 358
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>LEU3_BUCUH (Q9EVH8) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 29.3 bits (64), Expect = 9.4
 Identities = 31/134 (23%), Positives = 58/134 (43%)
 Frame = -2

Query: 606 CKNYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 427
           C N   D+ SD  A   GS+G++ S         +  E A G+           G+ + N
Sbjct: 245 CSNLFGDIISDECAVITGSIGMLPSASFNEKNFGL-YEPAGGSAP------DIAGKNTAN 297

Query: 426 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTR 247
            IA I + +  + +  KL+      + A K+++A   ++++G  T D++           
Sbjct: 298 PIAQILSLSMLVRYGMKLN------KIADKIDDAVALSLKAGYRTADIS---------ND 342

Query: 246 SDYLNTEEFIDAVA 205
           +++L T E  D +A
Sbjct: 343 NNFLKTNEMGDVIA 356
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>LEU3_PSEHT (Q3IJS3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 358

 Score = 29.3 bits (64), Expect = 9.4
 Identities = 34/117 (29%), Positives = 50/117 (42%), Gaps = 5/117 (4%)
 Frame = -2

Query: 606 CKNYDXDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 427
           C N   D+ SD  A   GS+GL+ S  +   G  +  E A G+           G+   N
Sbjct: 245 CDNLFGDILSDECAMITGSMGLLPSASLNQSGFGL-YEPAGGSAP------DIAGKGVAN 297

Query: 426 SIASIFAWTRGLAHRAKLDDNARLLEFA-QKLEEACVGTVE----SGKMTKDLALLV 271
            IA I +    L +    D+ AR +E A  +   A VGT +    +G  T D+A  +
Sbjct: 298 PIAQILSAALMLRYSLGQDEAARTIEKAVAEAVAAGVGTPDIFPNAGYTTNDVAAAI 354
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>SYNJ1_RAT (Q62910) Synaptojanin-1 (EC 3.1.3.36) (Synaptic|
           inositol-1,4,5-trisphosphate 5-phosphatase 1)
          Length = 1574

 Score = 29.3 bits (64), Expect = 9.4
 Identities = 28/88 (31%), Positives = 39/88 (44%), Gaps = 12/88 (13%)
 Frame = -2

Query: 477 VTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLE-------FAQKLEEA-- 325
           VTR   V +     + +SI+ I+A T  L  +AKL D AR +        F    +EA  
Sbjct: 418 VTRFQEVFRSMWSVNGDSISKIYAGTGALEGKAKLKDGARSVTRTIQNNFFDSSKQEAID 477

Query: 324 ---CVGTVESGKMTKDLALLVHGSSKVT 250
                 T+ S    K  ALL  GS +V+
Sbjct: 478 VLLLGNTLNSDLADKARALLTTGSLRVS 505
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>SYNJ1_MOUSE (Q8CHC4) Synaptojanin-1 (EC 3.1.3.36) (Synaptic|
           inositol-1,4,5-trisphosphate 5-phosphatase 1)
          Length = 1574

 Score = 29.3 bits (64), Expect = 9.4
 Identities = 28/88 (31%), Positives = 39/88 (44%), Gaps = 12/88 (13%)
 Frame = -2

Query: 477 VTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLE-------FAQKLEEA-- 325
           VTR   V +     + +SI+ I+A T  L  +AKL D AR +        F    +EA  
Sbjct: 418 VTRFQEVFRSMWSVNGDSISKIYAGTGALEGKAKLKDGARSVTRTIQNNFFDSSKQEAID 477

Query: 324 ---CVGTVESGKMTKDLALLVHGSSKVT 250
                 T+ S    K  ALL  GS +V+
Sbjct: 478 VLLLGNTLNSDLADKARALLTTGSLRVS 505
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>SYNJ1_HUMAN (O43426) Synaptojanin-1 (EC 3.1.3.36) (Synaptic|
           inositol-1,4,5-trisphosphate 5-phosphatase 1)
          Length = 1575

 Score = 29.3 bits (64), Expect = 9.4
 Identities = 28/88 (31%), Positives = 39/88 (44%), Gaps = 12/88 (13%)
 Frame = -2

Query: 477 VTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLE-------FAQKLEEA-- 325
           VTR   V +     + +SI+ I+A T  L  +AKL D AR +        F    +EA  
Sbjct: 418 VTRFQEVFRSMWSVNGDSISKIYAGTGALEGKAKLKDGARSVTRTIQNNFFDSSKQEAID 477

Query: 324 ---CVGTVESGKMTKDLALLVHGSSKVT 250
                 T+ S    K  ALL  GS +V+
Sbjct: 478 VLLLGNTLNSDLADKARALLTTGSLRVS 505


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 78,948,706
Number of Sequences: 219361
Number of extensions: 1466169
Number of successful extensions: 4010
Number of sequences better than 10.0: 81
Number of HSP's better than 10.0 without gapping: 3903
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3990
length of database: 80,573,946
effective HSP length: 107
effective length of database: 57,102,319
effective search space used: 5424720305
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
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