ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | rbags10p18 |
|---|---|
| Clone Library Name | barley_pub |
>CP51_WHEAT (P93596) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Obtusifoliol 14-alpha demethylase) (Fragment) Length = 453 Score = 341 bits (874), Expect = 1e-93 Identities = 163/165 (98%), Positives = 164/165 (99%) Frame = -3 Query: 700 DKIDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATS 521 DKIDHDILAEMDVLYRCIK ALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATS Sbjct: 289 DKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATS 348 Query: 520 PAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAI 341 PAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAI Sbjct: 349 PAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAI 408 Query: 340 WTHLLRNFEFELVSPFPENDWNAMVVGIKGEVMVNYKRRKLVVDN 206 WTHLLRNFEFELVSPFPENDWNAMVVGIKGEVMVNYKRRKL+VDN Sbjct: 409 WTHLLRNFEFELVSPFPENDWNAMVVGIKGEVMVNYKRRKLIVDN 453
>CP51_SORBI (P93846) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Obtusifoliol 14-alpha demethylase) Length = 492 Score = 330 bits (847), Expect = 2e-90 Identities = 156/165 (94%), Positives = 161/165 (97%) Frame = -3 Query: 700 DKIDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATS 521 DKIDHDILAEMDVLYRCIK ALRLHPPLIMLLRQSHSDF+VTT+EGKE+DIPKGHIVATS Sbjct: 328 DKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFTVTTKEGKEYDIPKGHIVATS 387 Query: 520 PAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAI 341 P+FANRLPHI+KNPDSYDPDRF GREEDK AGAFSYISFGGGRHGCLGEPFAYLQIKAI Sbjct: 388 PSFANRLPHIYKNPDSYDPDRFGPGREEDKAAGAFSYISFGGGRHGCLGEPFAYLQIKAI 447 Query: 340 WTHLLRNFEFELVSPFPENDWNAMVVGIKGEVMVNYKRRKLVVDN 206 WTHLLRNFEFELVSPFPENDWNAMVVGIKGEVMVNYKRRKLVVDN Sbjct: 448 WTHLLRNFEFELVSPFPENDWNAMVVGIKGEVMVNYKRRKLVVDN 492
>CP51_MYCVN (Q5IZM4) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (P450-14DM) Length = 452 Score = 127 bits (319), Expect = 3e-29 Identities = 69/161 (42%), Positives = 99/161 (61%), Gaps = 3/161 (1%) Frame = -3 Query: 697 KIDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSP 518 ++ L ++ L +K LRLHPPLI+L+R + +F V + I KG +VA SP Sbjct: 296 EVSFHALRQIPSLDNALKETLRLHPPLIILMRVAQDEFEVAG-----YPIHKGQMVAASP 350 Query: 517 AFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIW 338 A +NR+P F NPD +DPDR+ R+ED + +++I FG G+H C+G FA +QIKAI+ Sbjct: 351 AISNRIPEDFPNPDDFDPDRYEKPRQEDLI-NRWTWIPFGAGKHRCVGAAFAQMQIKAIF 409 Query: 337 THLLRNFEFELVSPFPE---NDWNAMVVGIKGEVMVNYKRR 224 + LLR +EFE+ P PE ND + MVV + V Y+RR Sbjct: 410 SVLLREYEFEMAQP-PESYQNDHSKMVVQLARPAKVRYRRR 449
>CP51_MYCTU (P0A512) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (P450-14DM) Length = 451 Score = 113 bits (283), Expect = 5e-25 Identities = 65/155 (41%), Positives = 93/155 (60%), Gaps = 3/155 (1%) Frame = -3 Query: 679 LAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 500 L ++ L +K LRLHPPLI+L+R + +F V I +G +VA SPA +NR+ Sbjct: 301 LRQIPQLENVLKETLRLHPPLIILMRVAKGEFEVQGHR-----IHEGDLVAASPAISNRI 355 Query: 499 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 320 P F +P + P R+ R+ED + +++I FG GRH C+G FA +QIKAI++ LLR Sbjct: 356 PEDFPDPHDFVPARYEQPRQED-LLNRWTWIPFGAGRHRCVGAAFAIMQIKAIFSVLLRE 414 Query: 319 FEFELVSPFPE---NDWNAMVVGIKGEVMVNYKRR 224 +EFE+ P PE ND + MVV + V Y+RR Sbjct: 415 YEFEMAQP-PESYRNDHSKMVVQLAQPACVRYRRR 448
>CP51_MYCBO (P0A513) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (P450-14DM) Length = 451 Score = 113 bits (283), Expect = 5e-25 Identities = 65/155 (41%), Positives = 93/155 (60%), Gaps = 3/155 (1%) Frame = -3 Query: 679 LAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 500 L ++ L +K LRLHPPLI+L+R + +F V I +G +VA SPA +NR+ Sbjct: 301 LRQIPQLENVLKETLRLHPPLIILMRVAKGEFEVQGHR-----IHEGDLVAASPAISNRI 355 Query: 499 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 320 P F +P + P R+ R+ED + +++I FG GRH C+G FA +QIKAI++ LLR Sbjct: 356 PEDFPDPHDFVPARYEQPRQED-LLNRWTWIPFGAGRHRCVGAAFAIMQIKAIFSVLLRE 414 Query: 319 FEFELVSPFPE---NDWNAMVVGIKGEVMVNYKRR 224 +EFE+ P PE ND + MVV + V Y+RR Sbjct: 415 YEFEMAQP-PESYRNDHSKMVVQLAQPACVRYRRR 448
>CP51A_PONPY (Q5RE72) Cytochrome P450 51A1 (EC 1.14.13.70) (CYPLI) (P450LI)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (LDM) (P450-14DM) (P45014DM) Length = 503 Score = 105 bits (261), Expect = 2e-22 Identities = 58/159 (36%), Positives = 95/159 (59%), Gaps = 2/159 (1%) Frame = -3 Query: 694 IDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPA 515 + +D L ++++L RCIK LRL PP+++++R + + +V + IP GH V SP Sbjct: 352 LTYDQLKDLNLLDRCIKETLRLRPPIMIMMRMARTPQTVAG-----YTIPPGHQVCVSPT 406 Query: 514 FANRLPHIFKNPDSYDPDRFAAGREEDKVAGA-FSYISFGGGRHGCLGEPFAYLQIKAIW 338 RL + ++PDR+ +++ +G F+Y+ FG GRH C+GE FAY+QIK IW Sbjct: 407 VNQRLKDSWVERLDFNPDRYL---QDNPASGEKFAYVPFGAGRHRCIGENFAYVQIKTIW 463 Query: 337 THLLRNFEFELVSP-FPENDWNAMVVGIKGEVMVNYKRR 224 + +LR +EF+L+ FP ++ M+ + V + YKRR Sbjct: 464 STMLRLYEFDLIDGYFPTVNYTTMIHTPENPV-IRYKRR 501
>CP51A_HUMAN (Q16850) Cytochrome P450 51A1 (EC 1.14.13.70) (CYPLI) (P450LI)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (LDM) (P450-14DM) (P45014DM) Length = 503 Score = 105 bits (261), Expect = 2e-22 Identities = 58/159 (36%), Positives = 95/159 (59%), Gaps = 2/159 (1%) Frame = -3 Query: 694 IDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPA 515 + +D L ++++L RCIK LRL PP+++++R + + +V + IP GH V SP Sbjct: 352 LTYDQLKDLNLLDRCIKETLRLRPPIMIMMRMARTPQTVAG-----YTIPPGHQVCVSPT 406 Query: 514 FANRLPHIFKNPDSYDPDRFAAGREEDKVAGA-FSYISFGGGRHGCLGEPFAYLQIKAIW 338 RL + ++PDR+ +++ +G F+Y+ FG GRH C+GE FAY+QIK IW Sbjct: 407 VNQRLKDSWVERLDFNPDRYL---QDNPASGEKFAYVPFGAGRHRCIGENFAYVQIKTIW 463 Query: 337 THLLRNFEFELVSP-FPENDWNAMVVGIKGEVMVNYKRR 224 + +LR +EF+L+ FP ++ M+ + V + YKRR Sbjct: 464 STMLRLYEFDLIDGYFPTVNYTTMIHTPENPV-IRYKRR 501
>CP51A_BOVIN (Q4PJW3) Cytochrome P450 51A1 (EC 1.14.13.70) (CYPLI) (P450LI)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (LDM) (P450-14DM) (P45014DM) Length = 502 Score = 104 bits (259), Expect = 3e-22 Identities = 58/159 (36%), Positives = 93/159 (58%), Gaps = 2/159 (1%) Frame = -3 Query: 694 IDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPA 515 + +D L ++++L RCIK LRL PP++ ++R + + +V + IP GH V SP Sbjct: 351 LTYDQLKDLNLLDRCIKETLRLRPPIMTMMRLAKTPLTVAG-----YTIPPGHQVCVSPT 405 Query: 514 FANRLPHIFKNPDSYDPDRFAAGREEDKVAGA-FSYISFGGGRHGCLGEPFAYLQIKAIW 338 RL + ++PDR+ E+ +G F+Y+ FG GRH C+GE FAY+QIK IW Sbjct: 406 VNQRLKDSWVERLDFNPDRYL---EDSPASGEKFAYVPFGAGRHRCIGENFAYVQIKTIW 462 Query: 337 THLLRNFEFELVSP-FPENDWNAMVVGIKGEVMVNYKRR 224 + +LR +EF+L+ FP ++ M + + ++ YKRR Sbjct: 463 STMLRLYEFDLIDGYFPTVNYTTM-IHTPEKPIIRYKRR 500
>CP51A_PIG (O46420) Cytochrome P450 51A1 (EC 1.14.13.70) (CYPLI) (P450LI)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (LDM) (P450-14DM) Length = 503 Score = 103 bits (258), Expect = 4e-22 Identities = 58/159 (36%), Positives = 94/159 (59%), Gaps = 2/159 (1%) Frame = -3 Query: 694 IDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPA 515 + +D L ++++L RCIK LRL PP++ ++R + + +V + IP GH V SP Sbjct: 352 LTYDQLKDLNLLDRCIKETLRLRPPIMTMMRMAKTPQTVAG-----YTIPPGHQVCVSPT 406 Query: 514 FANRLPHIFKNPDSYDPDRFAAGREEDKVAGA-FSYISFGGGRHGCLGEPFAYLQIKAIW 338 RL + ++PDR+ +++ +G F+Y+ FG GRH C+GE FAY+QIK IW Sbjct: 407 VNQRLKDSWVERLDFNPDRYL---QDNPASGEKFAYVPFGAGRHRCIGENFAYVQIKTIW 463 Query: 337 THLLRNFEFELVSP-FPENDWNAMVVGIKGEVMVNYKRR 224 + +LR +EF+L+ FP ++ M+ + V + YKRR Sbjct: 464 STMLRLYEFDLIDGYFPTVNYTTMIHTPENPV-IRYKRR 501
>CP51A_RAT (Q64654) Cytochrome P450 51A1 (EC 1.14.13.70) (CYPLI) (P450LI)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (LDM) (P450-14DM) Length = 503 Score = 103 bits (256), Expect = 7e-22 Identities = 57/159 (35%), Positives = 95/159 (59%), Gaps = 2/159 (1%) Frame = -3 Query: 694 IDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPA 515 + ++ L ++++L RCIK LRL PP++ ++R + + +V + IP GH V SP Sbjct: 352 LTYEQLKDLNLLDRCIKETLRLRPPIMTMMRMAKTPQTVAG-----YTIPPGHQVCVSPT 406 Query: 514 FANRLPHIFKNPDSYDPDRFAAGREEDKVAGA-FSYISFGGGRHGCLGEPFAYLQIKAIW 338 RL + ++PDR+ +++ +G F+Y+ FG GRH C+GE FAY+QIK IW Sbjct: 407 VNQRLKDSWVERLDFNPDRYL---QDNPASGEKFAYVPFGAGRHRCIGENFAYVQIKTIW 463 Query: 337 THLLRNFEFELVSP-FPENDWNAMVVGIKGEVMVNYKRR 224 + +LR +EF+L++ FP ++ M+ + V + YKRR Sbjct: 464 STMLRLYEFDLINGYFPSVNYTTMIHTPENPV-IRYKRR 501
>CP51_USTMA (P49602) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (P450-14DM) Length = 561 Score = 90.9 bits (224), Expect = 3e-18 Identities = 57/156 (36%), Positives = 79/156 (50%), Gaps = 27/156 (17%) Frame = -3 Query: 649 IKXALRLHPPLIMLLRQSHSDFSVT----------TREGKEFDIPKGHIVATSPAFANRL 500 +K LRLHPPL ++R SD +V + + IPKGH + +P + Sbjct: 385 VKETLRLHPPLHSIMRYVKSDLAVPPTLSSPTSTKSEPDAHYVIPKGHYIMAAPGVSQVD 444 Query: 499 PHIFKNPDSYDPDRF-----AAGRE---EDKVAGAFS---------YISFGGGRHGCLGE 371 P I+K+ D +DP R+ AA + EDK F Y+ FG GRH C+GE Sbjct: 445 PQIWKSSDQFDPHRWLDATTAAAMQDSGEDKQDFGFGMISTGANSPYLPFGAGRHRCIGE 504 Query: 370 PFAYLQIKAIWTHLLRNFEFELVSPFPENDWNAMVV 263 FAYLQI I +R F++ L S FP+ D+ +MVV Sbjct: 505 QFAYLQIGVILATFVRIFKWHLDSKFPDPDYQSMVV 540
>CP51_CUNEL (Q9UVC3) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (P450-14DM) Length = 512 Score = 86.3 bits (212), Expect = 8e-17 Identities = 54/174 (31%), Positives = 86/174 (49%), Gaps = 19/174 (10%) Frame = -3 Query: 685 DILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFAN 506 D L ++ +L I+ LRLHPP+ ++R+ +D V + G E IPKG+ + +P Sbjct: 341 DNLKDLPLLEAAIRETLRLHPPIFQMMRRVVADKIVYEKNGME--IPKGNFICAAPGVTQ 398 Query: 505 RLPHIFKNPDSYDPDRFAAGREE------------DKVAGAFS------YISFGGGRHGC 380 P F P +Y+P R+ + D GA ++ FG GRH C Sbjct: 399 VDPTYFNEPTTYNPYRWIEKTDPVHQLEQGDDANIDYGFGAVGISSKSPFLPFGAGRHRC 458 Query: 379 LGEPFAYLQIKAIWTHLLRNFEFEL-VSPFPENDWNAMVVGIKGEVMVNYKRRK 221 +GE F YLQ+K + + +R F+F+L P++D+ +MVV + V Y R+ Sbjct: 459 IGEQFGYLQLKTVISTFIRTFDFDLDGKSVPKSDYTSMVVVPEHTAKVRYTWRE 512
>CP4CU_BLAGE (Q964T1) Cytochrome P450 4c21 (EC 1.14.14.1) (CYPIVC21)| Length = 501 Score = 84.3 bits (207), Expect = 3e-16 Identities = 46/127 (36%), Positives = 71/127 (55%) Frame = -3 Query: 679 LAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 500 L M+ L R IK +LRLHP +I +R++H DF + + IP G + S F +R Sbjct: 355 LNNMNYLERVIKESLRLHPSVIYFVREAHQDFELGG-----YTIPAGTNIDFSVPFIHRN 409 Query: 499 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 320 P IF NP ++PD F R ++ ++YI F G C+G+ FA L+ K + ++LLR+ Sbjct: 410 PEIFPNPRCFNPDNFLPDRVVNR--HPYAYIPFSAGPRNCIGQRFALLEEKVVLSYLLRH 467 Query: 319 FEFELVS 299 + F V+ Sbjct: 468 YRFRTVN 474
>CP51_ASHGO (Q759W0) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (P450-14DM) Length = 529 Score = 84.0 bits (206), Expect = 4e-16 Identities = 54/175 (30%), Positives = 87/175 (49%), Gaps = 17/175 (9%) Frame = -3 Query: 697 KIDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSP 518 ++ +++L EM +L + IK LR+H PL L R+ D V + IPK H V SP Sbjct: 352 ELTYELLQEMPLLNQVIKETLRMHHPLHSLFRKVTRDMPVPNTS---YVIPKDHYVLASP 408 Query: 517 AFANRLPHIFKNPDSYDPDRF--------AAGREEDKVAGAFS------YISFGGGRHGC 380 F + F N ++P R+ + G + D GA S Y+ FGGGRH C Sbjct: 409 GFCHLSEEYFPNAKEFNPHRWDNDAASSVSTGEKVDYGFGAISKGVSSPYLPFGGGRHRC 468 Query: 379 LGEPFAYLQIKAIWTHLLRNFEFEL---VSPFPENDWNAMVVGIKGEVMVNYKRR 224 +GE FAY+Q+ I++ ++R+ ++ + P D+ +MV + ++RR Sbjct: 469 IGEGFAYMQLGTIFSVVVRSMKWHFPADMKGVPNPDFTSMVTLPSEPCRIAWERR 523
>CP51_CANAL (P10613) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (P450-14DM) Length = 528 Score = 79.3 bits (194), Expect = 1e-14 Identities = 50/163 (30%), Positives = 79/163 (48%), Gaps = 19/163 (11%) Frame = -3 Query: 694 IDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPA 515 + ++ L ++ + IK LR+H PL + R+ + + + +PKGH V SP Sbjct: 351 LTYEDLQKLPSVNNTIKETLRMHMPLHSIFRKVTNPLRIPETN---YIVPKGHYVLVSPG 407 Query: 514 FANRLPHIFKNPDSYDPDR------------FAAGREEDKVAGAFS------YISFGGGR 389 +A+ F NP+ +DP R F + E D G S Y+ FGGGR Sbjct: 408 YAHTSERYFDNPEDFDPTRWDTAAAKANSVSFNSSDEVDYGFGKVSKGVSSPYLPFGGGR 467 Query: 388 HGCLGEPFAYLQIKAIWTHLLRNFEFELVS-PFPENDWNAMVV 263 H C+GE FAY+Q+ I T + N + + P+ D+++MVV Sbjct: 468 HRCIGEQFAYVQLGTILTTFVYNLRWTIDGYKVPDPDYSSMVV 510
>CP51_YEAST (P10614) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (P450-14DM) Length = 530 Score = 77.8 bits (190), Expect = 3e-14 Identities = 52/174 (29%), Positives = 82/174 (47%), Gaps = 16/174 (9%) Frame = -3 Query: 697 KIDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSP 518 ++ +D+L EM +L + IK LR+H PL L R+ D V + IP G+ V SP Sbjct: 354 ELTYDLLQEMPLLNQTIKETLRMHHPLHSLFRKVMKDMHVPNTS---YVIPAGYHVLVSP 410 Query: 517 AFANRLPHIFKNPDSYDPDR--------FAAGREEDKVAGAFS------YISFGGGRHGC 380 + + F N ++ R ++ G E D GA S Y+ FGGGRH C Sbjct: 411 GYTHLRDEYFPNAHQFNIHRWNKDSASSYSVGEEVDYGFGAISKGVSSPYLPFGGGRHRC 470 Query: 379 LGEPFAYLQIKAIWTHLLRNFEFELV--SPFPENDWNAMVVGIKGEVMVNYKRR 224 +GE FAY Q+ + + +R ++ P D+ +MV G + +++R Sbjct: 471 IGEHFAYCQLGVLMSIFIRTLKWHYPEGKTVPPPDFTSMVTLPTGPAKIIWEKR 524
>CP136_MYCTU (P95099) Putative cytochrome P450 136 (EC 1.14.-.-)| Length = 492 Score = 77.8 bits (190), Expect = 3e-14 Identities = 50/154 (32%), Positives = 81/154 (52%), Gaps = 2/154 (1%) Frame = -3 Query: 694 IDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPA 515 +D + L +++ L + ++RL P+ +RQ+ D + + +PKG V P Sbjct: 341 LDIESLEQLESLDLVMNESIRLVTPVQWAMRQTVRDTELLG-----YYLPKGTNVIAYPG 395 Query: 514 FANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWT 335 +RLP I+ +P ++DP+RF R E K +++ FGGG H C+G F L+IK I Sbjct: 396 MNHRLPEIWTDPLTFDPERFTEPRNEHK-RHRYAFTPFGGGVHKCIGMVFDQLEIKTILH 454 Query: 334 HLLRNFEFELVSP--FPENDWNAMVVGIKGEVMV 239 LLR + EL P P D++AM + + G +V Sbjct: 455 RLLRRYRLELSRPDYQPRWDYSAMPIPMDGMPIV 488
>CP51_SCHPO (Q09736) Probable cytochrome P450 51 (EC 1.14.13.70) (CYPLI)| (P450-LIA1) (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (P450-14DM) Length = 495 Score = 77.4 bits (189), Expect = 4e-14 Identities = 48/171 (28%), Positives = 79/171 (46%), Gaps = 13/171 (7%) Frame = -3 Query: 697 KIDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSP 518 ++ D +M +L I+ LRLHPP+ +R+ D V G + IP + + +P Sbjct: 327 ELKFDQYKDMPLLNYVIQETLRLHPPIHSHMRKVKRDLPVP---GSKIVIPANNYLLAAP 383 Query: 517 AFANRLPHIFKNPDSYDPDRFAAGREEDKVA-------------GAFSYISFGGGRHGCL 377 F + +DP R+ ED+ A A Y+ FG GRH C+ Sbjct: 384 GLTATEEEYFTHATDFDPKRWNDRVNEDENAEQIDYGYGLVTKGAASPYLPFGAGRHRCI 443 Query: 376 GEPFAYLQIKAIWTHLLRNFEFELVSPFPENDWNAMVVGIKGEVMVNYKRR 224 GE FAY+ + I + + ++ + L+ P D+++MV G V + +KRR Sbjct: 444 GEQFAYMHLSTIISKFVHDYTWTLIGKVPNVDYSSMVALPLGPVKIAWKRR 494
>CP51_CANTR (P14263) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (P450-14DM) Length = 528 Score = 76.6 bits (187), Expect = 7e-14 Identities = 49/162 (30%), Positives = 81/162 (50%), Gaps = 19/162 (11%) Frame = -3 Query: 694 IDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPA 515 + ++ L ++ ++ IK LR+H PL + R+ + V + + IPKGH V S Sbjct: 351 LTYEDLQKLPLVNNTIKETLRMHMPLHSIFRKVMNPLRVPNTK---YVIPKGHYVLVSAG 407 Query: 514 FANRLPHIFKNPDSYDPDRFAAG---------REEDKVAGAFS---------YISFGGGR 389 +A+ F++P+ ++P R+ + ED V F Y+ FGGGR Sbjct: 408 YAHTSDRWFEHPEHFNPRRWESDDTKASAVSFNSEDTVDYGFGKISKGVSSPYLPFGGGR 467 Query: 388 HGCLGEPFAYLQIKAIWTHLLRNFEFEL-VSPFPENDWNAMV 266 H C+GE FAY+Q+ I T + NF++ L P+ D+ +MV Sbjct: 468 HRCIGEQFAYVQLGTILTTYIYNFKWRLNGDKVPDVDYQSMV 509
>CP4D1_DROSI (O16805) Cytochrome P450 4d1 (EC 1.14.-.-) (CYPIVD1)| Length = 512 Score = 76.3 bits (186), Expect = 9e-14 Identities = 40/136 (29%), Positives = 73/136 (53%) Frame = -3 Query: 694 IDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPA 515 + +++L ++ + C+K LR++P + +L R+ D + + IP G + SP Sbjct: 358 VSYELLNQLHYVDLCVKETLRMYPSVPLLGRKVLEDCEINGKL-----IPAGTNIGISPL 412 Query: 514 FANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWT 335 + R +F P+S+ P+RF +K+ ++YI F G C+G+ FA L+IKAI Sbjct: 413 YLGRREELFSEPNSFKPERFDVVTTAEKL-NPYAYIPFSAGPRNCIGQKFAMLEIKAIVA 471 Query: 334 HLLRNFEFELVSPFPE 287 ++LR++E + V E Sbjct: 472 NVLRHYEVDFVGDSSE 487
>CP4D1_DROME (P33269) Cytochrome P450 4d1 (EC 1.14.-.-) (CYPIVD1)| Length = 512 Score = 76.3 bits (186), Expect = 9e-14 Identities = 40/136 (29%), Positives = 73/136 (53%) Frame = -3 Query: 694 IDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPA 515 + +++L ++ + C+K LR++P + +L R+ D + + IP G + SP Sbjct: 358 VSYELLNQLHYVDLCVKETLRMYPSVPLLGRKVLEDCEINGKL-----IPAGTNIGISPL 412 Query: 514 FANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWT 335 + R +F P+S+ P+RF +K+ ++YI F G C+G+ FA L+IKAI Sbjct: 413 YLGRREELFSEPNSFKPERFDVVTTAEKL-NPYAYIPFSAGPRNCIGQKFAMLEIKAIVA 471 Query: 334 HLLRNFEFELVSPFPE 287 ++LR++E + V E Sbjct: 472 NVLRHYEVDFVGDSSE 487
>C4D10_DROMT (O18596) Cytochrome P450 4d10 (EC 1.14.-.-) (CYPIVD10)| Length = 513 Score = 75.1 bits (183), Expect = 2e-13 Identities = 46/159 (28%), Positives = 81/159 (50%), Gaps = 2/159 (1%) Frame = -3 Query: 694 IDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPA 515 + +D+L ++ + CIK LR++P + +L R+ + + + IP G + SP Sbjct: 359 VTYDLLNNLNYMDLCIKETLRMYPSVPLLGRKVLQECEINGKI-----IPAGTNIGISPL 413 Query: 514 FANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWT 335 F R I P+++ P+RF +K+ +YI F G C+G+ FA L+IKAI Sbjct: 414 FLGRSEDISSEPNTFKPERFDVVTSAEKL-NPHAYIPFSAGPRNCIGQKFAMLEIKAIAA 472 Query: 334 HLLRNFEFELVSPFPEND--WNAMVVGIKGEVMVNYKRR 224 ++LR++E E V E+ +++ K +M K+R Sbjct: 473 NVLRHYEIEFVGNAEESPVLIAELILRTKDPLMFKLKKR 511
>C4G15_DROME (Q9VYY4) Cytochrome P450 4g15 (EC 1.14.-.-) (CYPIVG15)| Length = 574 Score = 74.7 bits (182), Expect = 3e-13 Identities = 37/132 (28%), Positives = 72/132 (54%) Frame = -3 Query: 673 EMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRLPH 494 EM L RC+ LR++PP+ ++ R+ D + + + IP+G V + +R P Sbjct: 427 EMKYLERCLMETLRMYPPVPLIARELQEDLKLNSGN---YVIPRGATVTVATVLLHRNPK 483 Query: 493 IFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFE 314 ++ NP+ +DPD F R+ ++ ++++ F G C+G +A L++K + + +LRN Sbjct: 484 VYANPNVFDPDNFLPERQANR--HYYAFVPFSAGPRSCVGRKYAMLKLKILLSTILRN-- 539 Query: 313 FELVSPFPENDW 278 + + S E+D+ Sbjct: 540 YRVYSDLTESDF 551
>CP312_DROME (Q9VVN6) Probable cytochrome P450 312a1 (EC 1.14.-.-) (CYPCCCXIIA1)| Length = 510 Score = 74.3 bits (181), Expect = 3e-13 Identities = 43/131 (32%), Positives = 69/131 (52%) Frame = -3 Query: 700 DKIDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATS 521 + I + + +++ L CIK LR++P + R++ ++ ++ +F IPKG V S Sbjct: 356 EPISIEQVRQLEFLEACIKETLRMYPSGPLTARKATANCTIN-----DFFIPKGSDVIIS 410 Query: 520 PAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAI 341 P + R F +P + PDR+A G E A F I F G C+G+ +A + +K + Sbjct: 411 PIYMGRCKDFFPDPMVFKPDRWAIGAEPKIEATTF--IPFMAGARSCMGQRYAMVMLKMV 468 Query: 340 WTHLLRNFEFE 308 HLLRNF FE Sbjct: 469 LAHLLRNFLFE 479
>CP26A_HUMAN (O43174) Cytochrome P450 26A1 (EC 1.14.-.-) (Retinoic| acid-metabolizing cytochrome) (P450 retinoic acid-inactivating 1) (P450RAI) (hP450RAI) (Retinoic acid 4-hydroxylase) Length = 497 Score = 73.2 bits (178), Expect = 7e-13 Identities = 46/137 (33%), Positives = 73/137 (53%) Frame = -3 Query: 700 DKIDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATS 521 +K+D +IL ++ + IK LRL+PP+ R ++ T E + IPKG V S Sbjct: 343 NKLDMEILEQLKYIGCVIKETLRLNPPVPGGFR-----VALKTFELNGYQIPKGWNVIYS 397 Query: 520 PAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAI 341 + + IF N + ++PDRF ED A FS+I FGGG C+G+ FA + +K Sbjct: 398 ICDTHDVAEIFTNKEEFNPDRFMLPHPED--ASRFSFIPFGGGLRSCVGKEFAKILLKIF 455 Query: 340 WTHLLRNFEFELVSPFP 290 L R+ +++L++ P Sbjct: 456 TVELARHCDWQLLNGPP 472
>CP51_CANGA (P50859) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Sterol 14-alpha-demethylase) (Lanosterol 14-alpha demethylase) (P450-14DM) Length = 533 Score = 72.4 bits (176), Expect = 1e-12 Identities = 49/176 (27%), Positives = 83/176 (47%), Gaps = 18/176 (10%) Frame = -3 Query: 697 KIDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSP 518 ++ +D L M +L + IK LRLH PL L R+ D ++ + +P+ + V SP Sbjct: 355 ELTYDDLQNMPLLNQMIKETLRLHHPLHSLFRKVMRDVAIPNTS---YVVPRDYHVLVSP 411 Query: 517 AFANRLPHIFKNPDSYDPDRF---------AAGREEDKVAGAFS------YISFGGGRHG 383 + + F P+ ++ R+ A G E D GA S Y+ FGGGRH Sbjct: 412 GYTHLQEEFFPKPNEFNIHRWDGDAASSSAAGGDEVDYGFGAISKGVSSPYLPFGGGRHR 471 Query: 382 CLGEPFAYLQIKAIWTHLLRNFEFELVS---PFPENDWNAMVVGIKGEVMVNYKRR 224 C+GE FAY Q+ + + +R ++ + P +D+ +MV + +++R Sbjct: 472 CIGELFAYCQLGVLMSIFIRTMKWRYPTEGETVPPSDFTSMVTLPTAPAKIYWEKR 527
>CP4F5_RAT (P51870) Cytochrome P450 4F5 (EC 1.14.14.1) (CYPIVF5)| Length = 526 Score = 71.6 bits (174), Expect = 2e-12 Identities = 44/128 (34%), Positives = 69/128 (53%) Frame = -3 Query: 700 DKIDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATS 521 ++I+ D LA++ L CIK +LRLHPP I LLR+ D + +G+ IPKG+I S Sbjct: 370 EEIEWDDLAQLPFLTMCIKESLRLHPPAIDLLRRCTQD--IVLPDGRV--IPKGNICVIS 425 Query: 520 PAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAI 341 + P ++ +P+ +DP RF + E + S+I F G C+G+ FA ++K + Sbjct: 426 IFGIHHNPSVWPDPEVFDPFRFDS--ENRQKRSPLSFIPFSAGPRNCIGQTFAMNEMKVV 483 Query: 340 WTHLLRNF 317 L F Sbjct: 484 VALTLLRF 491
>CP51_PENIT (Q12664) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Sterol 14-alpha demethylase) (Eburicol 14-alpha-demethylase) (P450-14DM) Length = 515 Score = 71.6 bits (174), Expect = 2e-12 Identities = 47/151 (31%), Positives = 76/151 (50%), Gaps = 16/151 (10%) Frame = -3 Query: 673 EMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRLPH 494 ++ +L IK LRLH + L+R+ + V G +F +P H + +SP R Sbjct: 352 KLPLLRNVIKETLRLHSSIHTLMRKVKNPMPVP---GTDFVVPPSHTLLSSPGVTARDER 408 Query: 493 IFKNPDSYDPDRFAAGREEDKVA-------GAFS------YISFGGGRHGCLGEPFAYLQ 353 F++P +DP R+ + E + + GA S Y+ FG GRH C+GE FAYL Sbjct: 409 HFRDPLRWDPHRWESRVEVEDSSDTVDYGYGAVSKGTRSPYLPFGAGRHRCIGEKFAYLN 468 Query: 352 IKAIWTHLLRNFEF---ELVSPFPENDWNAM 269 ++ I L+R F F E + P+ D++++ Sbjct: 469 LEVIVATLVREFRFFNPEGMEGVPDTDYSSL 499
>CP4D2_DROME (Q27589) Cytochrome P450 4d2 (EC 1.14.-.-) (CYPIVD2)| Length = 501 Score = 71.2 bits (173), Expect = 3e-12 Identities = 46/143 (32%), Positives = 70/143 (48%) Frame = -3 Query: 679 LAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 500 L E+ + IK +LRLHPP+ M+ R D + GK IP G R Sbjct: 358 LGELKFMENVIKESLRLHPPVPMIGRWFAEDVEI---RGKH--IPAGTNFTMGIFVLLRD 412 Query: 499 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 320 P F++PD + P+RF A + ++YI F G C+G+ FA L++K+ + LLR+ Sbjct: 413 PEYFESPDEFRPERFDADVPQ---IHPYAYIPFSAGPRNCIGQKFAMLEMKSTVSKLLRH 469 Query: 319 FEFELVSPFPENDWNAMVVGIKG 251 FE + P P + N ++ G Sbjct: 470 FELLPLGPEPRHSMNIVLRSANG 492
>CP26A_MOUSE (O55127) Cytochrome P450 26A1 (EC 1.14.-.-) (Retinoic| acid-metabolizing cytochrome) (P450RAI) (Retinoic acid 4-hydroxylase) Length = 497 Score = 71.2 bits (173), Expect = 3e-12 Identities = 45/137 (32%), Positives = 72/137 (52%) Frame = -3 Query: 700 DKIDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATS 521 +K+D + L ++ + IK LRL+PP+ R ++ T E + IPKG V S Sbjct: 343 NKLDMETLEQLKYIGCVIKETLRLNPPVPGGFR-----VALKTFELNGYQIPKGWNVIYS 397 Query: 520 PAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAI 341 + + IF N + ++PDRF ED A FS+I FGGG C+G+ FA + +K Sbjct: 398 ICDTHDVADIFTNKEEFNPDRFIVPHPED--ASRFSFIPFGGGLRSCVGKEFAKILLKIF 455 Query: 340 WTHLLRNFEFELVSPFP 290 L R+ +++L++ P Sbjct: 456 TVELARHCDWQLLNGPP 472
>C4AA1_DROME (Q9V7G5) Probable cytochrome P450 4aa1 (EC 1.14.-.-) (CYPIVAA1)| Length = 514 Score = 69.7 bits (169), Expect = 8e-12 Identities = 37/122 (30%), Positives = 67/122 (54%) Frame = -3 Query: 679 LAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 500 L EM + CIK ALRL+P + ++ R+ + + + +P G V P +RL Sbjct: 362 LHEMRYMEMCIKEALRLYPSVPLIARKLGEEVRLA-----KHTLPAGSNVFICPYATHRL 416 Query: 499 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 320 HI+ +P+ + P+RF+ E++ ++++ F G C+G FA ++IK I + LLR+ Sbjct: 417 AHIYPDPEKFQPERFSPENSENR--HPYAFLPFSAGPRYCIGNRFAIMEIKTIVSRLLRS 474 Query: 319 FE 314 ++ Sbjct: 475 YQ 476
>CP6K1_BLAGE (Q964R0) Cytochrome P450 6k1 (EC 1.14.-.-) (CYPVIK1)| Length = 524 Score = 69.3 bits (168), Expect = 1e-11 Identities = 39/119 (32%), Positives = 60/119 (50%) Frame = -3 Query: 670 MDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRLPHI 491 M L+ + LR +PPL +L R D+ V G + I + V + +R P Sbjct: 373 MPYLHMVVSETLRKYPPLPLLDRVCLQDYKVP---GTDLIIERDTPVFIALLGLHRDPQY 429 Query: 490 FKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFE 314 + NP+ YDP+RF+ E + A++Y+ FG G H C+G F Y+ +K H+L FE Sbjct: 430 YPNPERYDPERFS--EENKRQRKAYTYLPFGEGPHNCIGLRFGYMAVKTALVHMLAEFE 486
>C6A13_DROME (Q9V4U9) Probable cytochrome P450 6a13 (EC 1.14.-.-) (CYPVIA13)| Length = 493 Score = 68.6 bits (166), Expect = 2e-11 Identities = 43/134 (32%), Positives = 67/134 (50%), Gaps = 5/134 (3%) Frame = -3 Query: 697 KIDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTRE-----GKEFDIPKGHI 533 K+ +D + EM L + + LR +P L LLR+S ++ + G + IP I Sbjct: 335 KLTYDSVQEMPYLDQVVAETLRKYPILPHLLRRSTKEYQIPNSNLILEPGSKIIIPVHSI 394 Query: 532 VATSPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQ 353 + P ++ +P+ +DP RF EE K F+Y+ FG G C+GE F LQ Sbjct: 395 --------HHDPELYPDPEKFDPSRFEP--EEIKARHPFAYLPFGEGPRNCIGERFGKLQ 444 Query: 352 IKAIWTHLLRNFEF 311 +K +LLR+F+F Sbjct: 445 VKVGLVYLLRDFKF 458
>CP6G2_DROME (Q9V675) Probable cytochrome P450 6g2 (EC 1.14.-.-) (CYPVIG2)| Length = 519 Score = 68.6 bits (166), Expect = 2e-11 Identities = 52/163 (31%), Positives = 80/163 (49%), Gaps = 6/163 (3%) Frame = -3 Query: 682 ILAEMDVLYRCIKXALRLHPPLIMLLRQSHS--DFSVTTREGKEFDIPKGHIVATSPAFA 509 ++ ++ + + LR++PPL L R+ S D+S+ K+F +PKG V P +A Sbjct: 361 MIESLEFMQMILLEVLRMYPPLPFLDRECTSGRDYSLAPFH-KKFVVPKGMPVYI-PCYA 418 Query: 508 NRL-PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTH 332 + P F P + P+RF+ E K+ ++Y+ FG G HGC+GE F YLQ K + Sbjct: 419 LHMDPQYFPQPRKFLPERFSP--ENRKLHTPYTYMPFGLGPHGCIGERFGYLQAKVGLVN 476 Query: 331 LLRNFEFELVSPFPEN---DWNAMVVGIKGEVMVNYKRRKLVV 212 LLRN P D A++ KG + + R L V Sbjct: 477 LLRNHMITTSERTPHRMQLDPKAIITQAKGGIHLRLVRDALGV 519
>CP4G1_DROME (Q9V3S0) Cytochrome P450 4g1 (EC 1.14.-.-) (CYPIVG1)| Length = 556 Score = 68.2 bits (165), Expect = 2e-11 Identities = 37/119 (31%), Positives = 62/119 (52%) Frame = -3 Query: 673 EMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRLPH 494 EM L R I LRL+PP+ ++ R+ D + + + +PKG V +R P Sbjct: 405 EMKYLERVILETLRLYPPVPLIARRLDYDLKLASGP---YTVPKGTTVIVLQYCVHRRPD 461 Query: 493 IFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNF 317 I+ NP +DPD F R ++ +S+I F G C+G +A L++K + + ++RN+ Sbjct: 462 IYPNPTKFDPDNFLPERMANR--HYYSFIPFSAGPRSCVGRKYAMLKLKVLLSTIVRNY 518
>CP4AA_MOUSE (O88833) Cytochrome P450 4A10 (EC 1.14.15.3) (CYPIVA10) (Lauric| acid omega-hydroxylase) (P450-LA-omega 1) (P452) Length = 509 Score = 68.2 bits (165), Expect = 2e-11 Identities = 44/127 (34%), Positives = 67/127 (52%) Frame = -3 Query: 694 IDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPA 515 I D L ++ CIK ALRL+PP+ ++R+ + SVT +G+ +PKG V S Sbjct: 360 ITWDHLDQIPYTTMCIKEALRLYPPVPGIVRELST--SVTFPDGRS--LPKGVQVTLSIY 415 Query: 514 FANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWT 335 + P ++ NP+ +DP RFA D + S++ F GG C+G+ FA ++K I Sbjct: 416 GLHHNPKVWPNPEVFDPSRFAP----DSPRHSHSFLPFSGGARNCIGKQFAMSELKVIVA 471 Query: 334 HLLRNFE 314 L FE Sbjct: 472 LTLLRFE 478
>CP4F6_RAT (P51871) Cytochrome P450 4F6 (EC 1.14.14.1) (CYPIVF6)| Length = 537 Score = 68.2 bits (165), Expect = 2e-11 Identities = 43/127 (33%), Positives = 70/127 (55%), Gaps = 1/127 (0%) Frame = -3 Query: 700 DKIDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATS 521 ++I+ D LA++ L CIK +LRLHPP++++ R D + +G+ IPKG+I S Sbjct: 368 EEIEWDDLAQLPFLTMCIKESLRLHPPVLLISRCCSQD--IVLPDGRV--IPKGNICVIS 423 Query: 520 PAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIK-A 344 + P ++ +P+ Y+P RF E + ++I F G C+G+ FA +IK A Sbjct: 424 IFGVHHNPSVWPDPEVYNPFRF--DPENPQKRSPLAFIPFSAGPRNCIGQTFAMSEIKVA 481 Query: 343 IWTHLLR 323 + LLR Sbjct: 482 LALTLLR 488
>CP6B6_HELAM (Q95031) Cytochrome P450 6B6 (EC 1.14.14.1) (CYPVIB6)| Length = 504 Score = 67.8 bits (164), Expect = 3e-11 Identities = 52/167 (31%), Positives = 76/167 (45%), Gaps = 6/167 (3%) Frame = -3 Query: 697 KIDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSP 518 K+ +D + EM + + LR++ + L R++ D+ + G + I K IV SP Sbjct: 345 KVTYDTVKEMKYMNKAFDETLRMYSIVEPLQRKATRDYKIP---GTDVVIEKDTIVLISP 401 Query: 517 AFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIW 338 + P + NP ++PDRF A EE +Y+ FG G+ C+G F LQ Sbjct: 402 RGIHYDPKYYDNPKQFNPDRFDA--EEVGKRHPCAYLPFGLGQRNCIGMRFGRLQSLLCI 459 Query: 337 THLLRNFEFELVSPFPENDWNAMV------VGIKGEVMVNYKRRKLV 215 T +L F E P D N V +G KG + VN RKLV Sbjct: 460 TKILSKFRIE---PSKNTDRNLQVEPHRGLIGPKGGIRVNVVPRKLV 503
>CP4AA_RAT (P08516) Cytochrome P450 4A10 (EC 1.14.15.3) (CYPIVA10) (Lauric| acid omega-hydroxylase) (P450-LA-omega 1) (P452) Length = 509 Score = 67.8 bits (164), Expect = 3e-11 Identities = 44/127 (34%), Positives = 67/127 (52%) Frame = -3 Query: 694 IDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPA 515 I D L ++ CIK ALRL+PP+ ++R+ + SVT +G+ +PKG V S Sbjct: 360 ITWDHLDQIPYTTMCIKEALRLYPPVPGIVRELST--SVTFPDGRS--LPKGIQVTLSIY 415 Query: 514 FANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWT 335 + P ++ NP+ +DP RFA D + S++ F GG C+G+ FA ++K I Sbjct: 416 GLHHNPKVWPNPEVFDPSRFAP----DSPRHSHSFLPFSGGARNCIGKQFAMSEMKVIVA 471 Query: 334 HLLRNFE 314 L FE Sbjct: 472 LTLLRFE 478
>CP9F2_DROME (Q9VG82) Probable cytochrome P450 9f2 (EC 1.14.-.-) (CYPIXF2)| Length = 516 Score = 67.4 bits (163), Expect = 4e-11 Identities = 36/129 (27%), Positives = 69/129 (53%) Frame = -3 Query: 697 KIDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSP 518 ++ ++ + M L + + LR P I + R+ + D + +G++ ++ KG ++ Sbjct: 358 ELTYEAIMGMKYLDQVVNEVLRKWPAAIAVDRECNKDITFDV-DGQKVEVKKGDVIWLPT 416 Query: 517 AFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIW 338 +R P F+NP +DP+RF+ +E F+Y FG G+ C+G FA L+ KA+ Sbjct: 417 CGFHRDPKYFENPMKFDPERFSDENKES--IQPFTYFPFGLGQRNCIGSRFALLEAKAVI 474 Query: 337 THLLRNFEF 311 +LL+++ F Sbjct: 475 YYLLKDYRF 483
>CP4AE_MOUSE (O35728) Cytochrome P450 4A14 precursor (EC 1.14.15.3) (CYPIVA14)| (Lauric acid omega-hydroxylase 3) (P450-LA-omega 3) Length = 507 Score = 67.0 bits (162), Expect = 5e-11 Identities = 44/124 (35%), Positives = 61/124 (49%) Frame = -3 Query: 685 DILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFAN 506 D L +M CIK ALRL+PP+I + R+ S VT +G+ IPKG S + Sbjct: 361 DHLGQMPYTTMCIKEALRLYPPVISVSRELSS--PVTFPDGR--SIPKGITATISIYGLH 416 Query: 505 RLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLL 326 P + NP +DP RFA D + +Y+ F GG C+G+ FA ++K L Sbjct: 417 HNPRFWPNPKVFDPSRFA----PDSSHHSHAYLPFSGGSRNCIGKQFAMNELKVAVALTL 472 Query: 325 RNFE 314 FE Sbjct: 473 LRFE 476
>CP4FB_HUMAN (Q9HBI6) Cytochrome P450 4F11 (EC 1.14.14.1) (CYPIVF11)| Length = 524 Score = 67.0 bits (162), Expect = 5e-11 Identities = 41/127 (32%), Positives = 68/127 (53%) Frame = -3 Query: 697 KIDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSP 518 +I+ D LA++ L CIK +LRLHPP+ ++ R DF + +G+ IPKG + + Sbjct: 369 EIEWDDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDFVLP--DGRV--IPKGIVCLINI 424 Query: 517 AFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIW 338 + P ++ +P+ YDP RF +E K ++I F G C+G+ FA ++K + Sbjct: 425 IGIHYNPTVWPDPEVYDPFRF--NQENIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVL 482 Query: 337 THLLRNF 317 L +F Sbjct: 483 ALTLLHF 489
>C6A14_DROME (Q9V4U7) Probable cytochrome P450 6a14 (EC 1.14.-.-) (CYPVIA14)| Length = 509 Score = 66.6 bits (161), Expect = 7e-11 Identities = 39/131 (29%), Positives = 65/131 (49%) Frame = -3 Query: 697 KIDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSP 518 ++++D+LA+M L + + LR HP L L+R++ D+ + + + KG + Sbjct: 354 ELNYDVLAQMTYLDQVLSETLRKHPLLPHLIRETTKDYQIPN---SDIVLDKGILALIPV 410 Query: 517 AFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIW 338 + P I+ P+ +DP RF EE K +Y+ FG G C+G F +Q K Sbjct: 411 HNIHHDPEIYPEPEKFDPSRFDP--EEVKNRHPMAYLPFGDGPRNCIGLRFGKIQAKIGL 468 Query: 337 THLLRNFEFEL 305 LLR F+F + Sbjct: 469 VSLLRRFKFSV 479
>CP6B7_HELAM (O61387) Cytochrome P450 6B7 (EC 1.14.14.1) (CYPVIB7)| Length = 504 Score = 66.2 bits (160), Expect = 9e-11 Identities = 51/167 (30%), Positives = 76/167 (45%), Gaps = 6/167 (3%) Frame = -3 Query: 697 KIDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSP 518 K+ +D + EM L + LR++ + L R++ D+ + G + I K +V SP Sbjct: 345 KVTYDTVKEMKYLNKVFDETLRMYSIVEPLQRKATRDYQIP---GTDVVIEKDTMVLISP 401 Query: 517 AFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIW 338 + P + NP ++PDRF A EE +Y+ FG G+ C+G F LQ Sbjct: 402 RGIHYDPKYYDNPKQFNPDRFDA--EEVGKRHPCAYLPFGLGQRNCIGMRFGRLQSLLCI 459 Query: 337 THLLRNFEFELVSPFPENDWNAMV------VGIKGEVMVNYKRRKLV 215 T +L F E P D N V +G KG + VN RK+V Sbjct: 460 TKILSKFRIE---PSKNTDRNLQVEPRRVTIGPKGGIRVNIVPRKIV 503
>THAS_PIG (P47787) Thromboxane-A synthase (EC 5.3.99.5) (TXA synthase) (TXS)| Length = 534 Score = 65.9 bits (159), Expect = 1e-10 Identities = 35/114 (30%), Positives = 57/114 (50%) Frame = -3 Query: 649 IKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRLPHIFKNPDSY 470 + LR++PP R++ D V + IP G ++ + + P + +P+++ Sbjct: 398 LSETLRMYPPAFRFTREAARDCEVLGQR-----IPAGTVLEVAVGALHHDPKHWPHPETF 452 Query: 469 DPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFE 308 DP+RF A E ++ F+Y+ FG G CLG L+IK H+LR F FE Sbjct: 453 DPERFTA--EAQRLQQPFTYLPFGAGPRSCLGVQLGLLEIKLTLLHILRKFRFE 504
>CP4FE_MOUSE (Q9EP75) Cytochrome P450 4F14 (EC 1.14.13.30) (Leukotriene-B4| omega-hydroxylase) (Leukotriene-B4 20-monooxygenase) (Cytochrome P450-LTB-omega) (Cyp4f-14) Length = 524 Score = 65.9 bits (159), Expect = 1e-10 Identities = 44/127 (34%), Positives = 69/127 (54%), Gaps = 1/127 (0%) Frame = -3 Query: 700 DKIDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATS 521 ++I+ D LA++ L CIK +LRLHPP+ ++ R D + +G+ IPKG I S Sbjct: 368 EEIEWDDLAQLPFLTMCIKESLRLHPPVTVISRCCTQD--ILLPDGR--TIPKGIICLIS 423 Query: 520 PAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIK-A 344 + P ++ +P+ YDP RF E K + ++I F G C+G+ FA ++K A Sbjct: 424 IFGIHHNPSVWPDPEVYDPFRF--DPENIKDSSPLAFIPFSAGPRNCIGQTFAMSEMKVA 481 Query: 343 IWTHLLR 323 + LLR Sbjct: 482 LALTLLR 488
>CP4FC_HUMAN (Q9HCS2) Cytochrome P450 4F12 (EC 1.14.14.1) (CYPIVF12)| Length = 524 Score = 65.9 bits (159), Expect = 1e-10 Identities = 40/129 (31%), Positives = 64/129 (49%) Frame = -3 Query: 697 KIDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSP 518 +I+ D LA++ L C+K +LRLHPP + R D + +G+ IPKG Sbjct: 369 EIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQD--IVLPDGRV--IPKGITCLIDI 424 Query: 517 AFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIW 338 + P ++ +P+ YDP RF E K ++I F G C+G+ FA ++K + Sbjct: 425 IGVHHNPTVWPDPEVYDPFRFDP--ENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVL 482 Query: 337 THLLRNFEF 311 +L +F F Sbjct: 483 ALMLLHFRF 491
>CP51_UNCNE (O14442) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Sterol 14-alpha demethylase) (Eburicol 14-alpha-demethylase) (P450-14DM) Length = 524 Score = 65.5 bits (158), Expect = 2e-10 Identities = 43/145 (29%), Positives = 72/145 (49%), Gaps = 17/145 (11%) Frame = -3 Query: 694 IDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPA 515 + ++ L+++ + +K LRLH P+ ++R+ + V G ++ IP H++ +SP Sbjct: 351 LQYEDLSKLQLHQNVLKEVLRLHAPIHSIMRKVKNPMIVP---GTKYVIPTSHVLISSPG 407 Query: 514 FANRLPHIFKNPDSYDPDRFAAGREE----DKV------------AGAFS-YISFGGGRH 386 ++ F +P +DP R+ G + D V GA S Y+ FG GRH Sbjct: 408 CTSQDATFFPDPLKWDPHRWDIGSGKVLGNDAVDEKYDYGYGLTSTGASSPYLPFGAGRH 467 Query: 385 GCLGEPFAYLQIKAIWTHLLRNFEF 311 C+GE FA LQ+ I ++R F F Sbjct: 468 RCIGEQFATLQLVTIMATMVRFFRF 492
>CP26A_CHICK (Q9PUB4) Cytochrome P450 26A1 (EC 1.14.-.-) (Retinoic acid| degrading enzyme CYP26) Length = 492 Score = 65.5 bits (158), Expect = 2e-10 Identities = 44/161 (27%), Positives = 79/161 (49%), Gaps = 10/161 (6%) Frame = -3 Query: 697 KIDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSP 518 +++ + L ++ IK LRL PP+ R ++ T E + IPKG V S Sbjct: 339 QLNMEFLEQLKYTGCVIKETLRLSPPVPGGFR-----IALKTLELNGYQIPKGWNVIYSI 393 Query: 517 AFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIW 338 + + +F + D ++PDRF + ED + FS+I FGGG C+G+ FA + +K Sbjct: 394 CDTHDVADLFTDKDEFNPDRFMSPSPED--SSRFSFIPFGGGLRSCVGKEFAKVLLKIFT 451 Query: 337 THLLRNFEFELVS----------PFPENDWNAMVVGIKGEV 245 L R+ +++L++ +P ++ A +G G++ Sbjct: 452 VELARSCDWQLLNGPPTMKTGPIVYPVDNLPAKFIGFSGQI 492
>CP6B4_PAPGL (Q27902) Cytochrome P450 6B4 (EC 1.14.14.1) (CYPVIB4)| (CYP6B4V1/CYP6B4V2) Length = 500 Score = 65.5 bits (158), Expect = 2e-10 Identities = 41/130 (31%), Positives = 64/130 (49%) Frame = -3 Query: 697 KIDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSP 518 +I +D L+EM L + LR +P +LLR + +D++V G + KG V S Sbjct: 343 EITYDTLSEMTYLTQVFHETLRKYPVADILLRNAKADYAVP---GTNVTLKKGQTVVVSG 399 Query: 517 AFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIW 338 + P + +P+ +DP+RF+ ++ A YI FG G+ CLG F Q++ Sbjct: 400 FGIHYDPKYYPDPEKFDPERFSPENVRNRHPCA--YIPFGAGQRKCLGMRFGQWQVQVCI 457 Query: 337 THLLRNFEFE 308 LL F FE Sbjct: 458 IKLLSKFRFE 467
>CP6B5_PAPGL (Q95036) Cytochrome P450 6B5 (EC 1.14.14.1) (CYPVIB5) (CYP6B5V1)| (Fragment) Length = 476 Score = 65.5 bits (158), Expect = 2e-10 Identities = 41/130 (31%), Positives = 64/130 (49%) Frame = -3 Query: 697 KIDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSP 518 +I +D L+EM L + LR +P +LLR + +D++V G + KG V S Sbjct: 343 EITYDTLSEMTYLTQVFHETLRKYPVADILLRNAKADYAVP---GTNVTLKKGQTVVVSG 399 Query: 517 AFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIW 338 + P + +P+ +DP+RF+ ++ A YI FG G+ CLG F Q++ Sbjct: 400 FGIHYDPKYYPDPEKFDPERFSPENVRNRHPCA--YIPFGAGQRKCLGMRFGQWQVQVCI 457 Query: 337 THLLRNFEFE 308 LL F FE Sbjct: 458 IKLLSKFRFE 467
>CP4F2_HUMAN (P78329) Cytochrome P450 4F2 (EC 1.14.13.30) (CYPIVF2)| (Leukotriene-B(4) omega-hydroxylase) (Leukotriene-B(4) 20-monooxygenase) (Cytochrome P450-LTB-omega) Length = 520 Score = 65.1 bits (157), Expect = 2e-10 Identities = 41/127 (32%), Positives = 64/127 (50%) Frame = -3 Query: 697 KIDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSP 518 +I+ D LA + L C+K +LRLHPP+ ++ R H + +G+ IPKG I S Sbjct: 369 EIEWDDLAHLPFLTMCMKESLRLHPPVPVISR--HVTQDIVLPDGRV--IPKGIICLISV 424 Query: 517 AFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIW 338 + P ++ +P+ YDP RF E K ++I F G C+G+ FA ++K + Sbjct: 425 FGTHHNPAVWPDPEVYDPFRF--DPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVL 482 Query: 337 THLLRNF 317 L F Sbjct: 483 ALTLLRF 489
>CP4F4_RAT (P51869) Cytochrome P450 4F4 (EC 1.14.14.1) (CYPIVF4)| Length = 522 Score = 65.1 bits (157), Expect = 2e-10 Identities = 42/126 (33%), Positives = 69/126 (54%), Gaps = 1/126 (0%) Frame = -3 Query: 697 KIDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSP 518 +I+ D LA++ L CIK +LRLHPP+ ++ R+ D + +G+ IPKG I + Sbjct: 369 EIEWDDLAQLPFLTMCIKESLRLHPPVTVISRRCTQD--IVLPDGRV--IPKGVICIINI 424 Query: 517 AFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIK-AI 341 + P ++ +P+ YDP RF +D+ ++I F G C+G+ FA ++K A+ Sbjct: 425 FATHHNPTVWPDPEVYDPFRFDPENIKDR--SPLAFIPFSAGPRNCIGQTFAMNEMKVAL 482 Query: 340 WTHLLR 323 LLR Sbjct: 483 ALTLLR 488
>CP11A_DASAM (Q92045) Cytochrome P450 11A1, mitochondrial precursor (EC| 1.14.15.6) (CYPXIA1) (P450(SCC)) (Cholesterol side-chain cleavage enzyme) (Cholesterol desmolase) (Fragment) Length = 514 Score = 64.7 bits (156), Expect = 3e-10 Identities = 38/125 (30%), Positives = 62/125 (49%) Frame = -3 Query: 682 ILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANR 503 +L + +L +K LRL+P I + R + D + + + IP G +V R Sbjct: 371 MLKSVPLLKCVVKETLRLYPVAISIQRYLNEDTVL-----QNYHIPAGTLVQLGLYAMGR 425 Query: 502 LPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLR 323 P IFKNP+ Y+P+R+ G + F ++ FG G C+G A Q+ + H+L+ Sbjct: 426 NPKIFKNPEQYNPERWLKGEDTH-----FRHLGFGFGPRQCIGRRIAETQMVLLMIHMLQ 480 Query: 322 NFEFE 308 NF+ E Sbjct: 481 NFKIE 485
>CP26C_HUMAN (Q6V0L0) Cytochrome P450 26C1 (EC 1.14.-.-)| Length = 522 Score = 64.7 bits (156), Expect = 3e-10 Identities = 42/123 (34%), Positives = 65/123 (52%), Gaps = 3/123 (2%) Frame = -3 Query: 649 IKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRLPHIFKNP-DS 473 +K LRL PP+ R + + T E + IPKG V S + ++++P + Sbjct: 373 VKEVLRLLPPVSGGYRTA-----LRTFELDGYQIPKGWSVMYSIRDTHETAAVYRSPPEG 427 Query: 472 YDPDRFAAGREEDKVAGA-FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSP 296 +DP+RF A RE+ + A + F YI FGGG CLG+ A ++ + L+R +EL +P Sbjct: 428 FDPERFGAAREDSRGASSRFHYIPFGGGARSCLGQELAQAVLQLLAVELVRTARWELATP 487 Query: 295 -FP 290 FP Sbjct: 488 AFP 490
>CP26B_HUMAN (Q9NR63) Cytochrome P450 26B1 (EC 1.14.-.-) (P450 26A2) (P450| retinoic acid-inactivating 2) (P450RAI-2) (Retinoic-acid metabolizing cytochrome) Length = 512 Score = 64.3 bits (155), Expect = 3e-10 Identities = 45/129 (34%), Positives = 61/129 (47%) Frame = -3 Query: 685 DILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFAN 506 D L+ + L IK +RL P+ R F + F IPKG V S + Sbjct: 346 DTLSGLRYLDCVIKEVMRLFTPISGGYRTVLQTFELDG-----FQIPKGWSVMYSIRDTH 400 Query: 505 RLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLL 326 +FK+ + +DPDRF+ R EDK G F Y+ FGGG CLG+ A L +K + L Sbjct: 401 DTAPVFKDVNVFDPDRFSQARSEDK-DGRFHYLPFGGGVRTCLGKHLAKLFLKVLAVELA 459 Query: 325 RNFEFELVS 299 FEL + Sbjct: 460 STSRFELAT 468
>CP4C3_DROME (Q9VA27) Cytochrome P450 4c3 (EC 1.14.-.-) (CYPIVC3)| Length = 535 Score = 64.3 bits (155), Expect = 3e-10 Identities = 41/130 (31%), Positives = 63/130 (48%), Gaps = 4/130 (3%) Frame = -3 Query: 679 LAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 500 L +M L CIK +LRL P + M+ R D ++ + +P G +R Sbjct: 389 LMDMRYLECCIKDSLRLFPSVPMMARMVGEDVNIGGKI-----VPAGTQAIIMTYALHRN 443 Query: 499 PHIFKNPDSYDPDRF----AAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTH 332 P +F P+ ++PD F AGR F+YI F G C+G+ FA L+ KA+ + Sbjct: 444 PRVFPKPEQFNPDNFLPENCAGRHP------FAYIPFSAGPRNCIGQKFAILEEKAVIST 497 Query: 331 LLRNFEFELV 302 +LR ++ E V Sbjct: 498 VLRKYKIEAV 507
>CP3AF_CAVPO (Q64406) Cytochrome P450 3A15 (EC 1.14.14.1) (CYPIIIA15)| Length = 503 Score = 63.9 bits (154), Expect = 4e-10 Identities = 41/127 (32%), Positives = 64/127 (50%), Gaps = 1/127 (0%) Frame = -3 Query: 688 HDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFA 509 +D++ EM+ L + LRL+P + R S DF + G F PKG +V P+FA Sbjct: 347 YDVMMEMEYLDMVVNETLRLYPVANRIERMSKKDFEIN---GMSF--PKGTLVMI-PSFA 400 Query: 508 -NRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTH 332 +R + PD + P+RF+ +E+ + Y+ FG G C+G A + +K Sbjct: 401 LHRDSKYWPEPDEFRPERFSKKNKEN--IDPYIYMPFGNGPRNCIGRRMALMNLKLALIR 458 Query: 331 LLRNFEF 311 LL+NF F Sbjct: 459 LLQNFSF 465
>CP4F1_RAT (P33274) Cytochrome P450 4F1 (EC 1.14.14.1) (CYPIVF1) (P450-A3)| Length = 524 Score = 63.9 bits (154), Expect = 4e-10 Identities = 43/127 (33%), Positives = 69/127 (54%), Gaps = 1/127 (0%) Frame = -3 Query: 700 DKIDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATS 521 ++I+ D LA++ L CIK +LRLHPP+ ++ R D + +G+ IPKG I S Sbjct: 368 EEIEWDDLAQLPFLTMCIKESLRLHPPVTVISRCCTQD--ILLPDGR--TIPKGIICLIS 423 Query: 520 PAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIK-A 344 + P ++ +P+ Y+P RF E K + ++I F G C+G+ FA ++K A Sbjct: 424 IFGIHHNPSVWPDPEVYNPFRF--DPENIKDSSPLAFIPFSAGPRNCIGQTFAMSEMKVA 481 Query: 343 IWTHLLR 323 + LLR Sbjct: 482 LALTLLR 488
>CP4B1_RAT (P15129) Cytochrome P450 4B1 (EC 1.14.14.1) (CYPIVB1) (P450-isozyme| 5) (P450 L-2) Length = 510 Score = 63.9 bits (154), Expect = 4e-10 Identities = 42/136 (30%), Positives = 68/136 (50%), Gaps = 4/136 (2%) Frame = -3 Query: 700 DKIDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATS 521 D D LA+M L C+K RL+PP+ + RQ + VT +G+ +P G +++ Sbjct: 352 DSFQWDDLAKMTYLTMCMKECFRLYPPVPQVYRQLNKP--VTFVDGRS--LPAGSLISLH 407 Query: 520 PAFANRLPHIFKNPDSYDPDRF----AAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQ 353 +R ++ +P+ +DP RF AAGR F+++ F G C+G+ FA + Sbjct: 408 IYALHRNSTVWPDPEVFDPLRFSPENAAGRHP------FAFMPFSAGPRNCIGQQFAMNE 461 Query: 352 IKAIWTHLLRNFEFEL 305 +K + L FEF L Sbjct: 462 MKVVTALCLLRFEFSL 477
>CP4D8_DROME (Q9VS79) Cytochrome P450 4d8 (EC 1.14.-.-) (CYPIVD8)| Length = 463 Score = 63.5 bits (153), Expect = 6e-10 Identities = 36/122 (29%), Positives = 59/122 (48%) Frame = -3 Query: 679 LAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 500 L E+ + IK +LR++PP+ ++ R+ +DF T + IP G + +R Sbjct: 314 LGELKYMECVIKESLRMYPPVPIVGRKLQTDFKYTHSVHGDGVIPAGSEIIIGIFGVHRQ 373 Query: 499 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 320 P F NPD + P+R E F I F G C+G+ FA L++K + ++R Sbjct: 374 PETFPNPDEFIPER----HENGSRVAPFKMIPFSAGPRNCIGQKFAQLEMKMMLAKIVRE 429 Query: 319 FE 314 +E Sbjct: 430 YE 431
>C77A3_SOYBN (O48928) Cytochrome P450 77A3 (EC 1.14.-.-)| Length = 513 Score = 63.2 bits (152), Expect = 8e-10 Identities = 44/143 (30%), Positives = 71/143 (49%), Gaps = 3/143 (2%) Frame = -3 Query: 697 KIDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIP-KGHIVATS 521 K+D + +M L+ +K LR HPP +L +H+ TT G +DIP ++ + Sbjct: 348 KVDEKDVEKMPYLHAVVKELLRKHPPTHFVL--THAVTEPTTLGG--YDIPIDANVEVYT 403 Query: 520 PAFANRLPHIFKNPDSYDPDRFAAGREEDKVAG--AFSYISFGGGRHGCLGEPFAYLQIK 347 PA A P + NP+ +DP+RF +G EE + G + FG GR C G A + I Sbjct: 404 PAIAED-PKNWLNPEKFDPERFISGGEEADITGVTGVKMMPFGVGRRICPGLAMATVHIH 462 Query: 346 AIWTHLLRNFEFELVSPFPENDW 278 + +++ FE+ P + D+ Sbjct: 463 LMMARMVQEFEWGAYPPEKKMDF 485
>CP4A4_RABIT (P10611) Cytochrome P450 4A4 precursor (EC 1.14.14.1) (CYPIVA4)| (Prostaglandin omega-hydroxylase) (P450-P-2) Length = 510 Score = 63.2 bits (152), Expect = 8e-10 Identities = 41/122 (33%), Positives = 63/122 (51%) Frame = -3 Query: 679 LAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 500 L +M CIK ALRL+PP+ + RQ VT +G+ +PKG I+ S + Sbjct: 366 LDQMPYTTMCIKEALRLYPPVPSVTRQLSKP--VTFPDGRS--LPKGVILFLSIYGLHYN 421 Query: 499 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 320 P +++NP+ +DP RFA D + +++ F GG C+G+ FA ++K L Sbjct: 422 PKVWQNPEVFDPFRFA----PDSAYHSHAFLPFSGGARNCIGKQFAMRELKVAVALTLVR 477 Query: 319 FE 314 FE Sbjct: 478 FE 479
>C97B2_SOYBN (O48921) Cytochrome P450 97B2 (EC 1.14.-.-)| Length = 576 Score = 63.2 bits (152), Expect = 8e-10 Identities = 42/148 (28%), Positives = 72/148 (48%), Gaps = 23/148 (15%) Frame = -3 Query: 679 LAEMDVLYRCIKXALRLHPPLIMLLRQS-HSDFSVTTREGKE--FDIPKGHIVATSPAFA 509 L E+ + + ALRL+P +L+R+S SD +G++ + IP G V S Sbjct: 397 LKELQYIRLIVVEALRLYPQPPLLIRRSLKSDVLPGGHKGEKDGYAIPAGTDVFISVYNL 456 Query: 508 NRLPHIFKNPDSYDPDRFAAGREEDKVAG--------------------AFSYISFGGGR 389 +R P+ + PD ++P+RF + +++ G F+++ FGGG Sbjct: 457 HRSPYFWDRPDDFEPERFLVQNKNEEIEGWAGLDPSRSPGALYPNEVISDFAFLPFGGGP 516 Query: 388 HGCLGEPFAYLQIKAIWTHLLRNFEFEL 305 C+G+ FA ++ T LL+NF+ EL Sbjct: 517 RKCVGDQFALMESTVALTMLLQNFDVEL 544
>CP4AC_MOUSE (Q91WL5) Cytochrome P450 4A12 (EC 1.14.14.1) (CYPIVA12)| Length = 508 Score = 63.2 bits (152), Expect = 8e-10 Identities = 41/122 (33%), Positives = 62/122 (50%) Frame = -3 Query: 679 LAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 500 L +M CIK ALR++PP+ + R+ S VT +G+ +PKG V S + Sbjct: 364 LDKMPYTTMCIKEALRIYPPVPSVSRELSSP--VTFPDGRS--LPKGIHVMLSFYGLHHN 419 Query: 499 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 320 P ++ NP+ +DP RFA G + S++ F GG C+G+ FA ++K L Sbjct: 420 PTVWPNPEVFDPSRFAPGSSRH----SHSFLPFSGGARNCIGKQFAMNELKVAVALTLLR 475 Query: 319 FE 314 FE Sbjct: 476 FE 477
>CP4F3_HUMAN (Q08477) Cytochrome P450 4F3 (EC 1.14.13.30) (CYPIVF3)| (Leukotriene-B(4) omega-hydroxylase) (Leukotriene-B(4) 20-monooxygenase) (Cytochrome P450-LTB-omega) Length = 520 Score = 62.8 bits (151), Expect = 1e-09 Identities = 39/119 (32%), Positives = 62/119 (52%) Frame = -3 Query: 697 KIDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSP 518 +I+ D LA++ L CIK +LRLHPP+ + R D + +G+ IPKG I S Sbjct: 369 EIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQD--IVLPDGRV--IPKGIICLISV 424 Query: 517 AFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAI 341 + P ++ +P+ YDP RF + K ++I F G C+G+ FA ++K + Sbjct: 425 FGTHHNPAVWPDPEVYDPFRF--DPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVV 481
>CP9E2_BLAGE (Q964T2) Cytochrome P450 9e2 (EC 1.14.-.-) (CYPIXE2)| Length = 533 Score = 62.8 bits (151), Expect = 1e-09 Identities = 36/136 (26%), Positives = 65/136 (47%) Frame = -3 Query: 697 KIDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSP 518 K+ ++ + M L + +LRL+PP I R+ ++ + + + G V Sbjct: 374 KLTYEAIHSMKYLDMVVSESLRLYPPAIFTDRKCVKNYRLPMEPS--YTLEPGDAVWIPI 431 Query: 517 AFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIW 338 + P + NP+ +DP+RF+ +++ F+Y+ FG G C+G FA ++ K Sbjct: 432 YAIHHDPKYYPNPEKFDPERFSDENKDN--IKPFTYLPFGSGPRNCIGNRFALMESKIAL 489 Query: 337 THLLRNFEFELVSPFP 290 HLL F ++VS P Sbjct: 490 VHLLCRFNLKVVSKTP 505
>CP3AT_PIG (P79401) Cytochrome P450 3A29 (EC 1.14.14.1) (CYPIIIA29)| Length = 503 Score = 62.8 bits (151), Expect = 1e-09 Identities = 35/127 (27%), Positives = 61/127 (48%) Frame = -3 Query: 688 HDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFA 509 +D LA+M+ L + LRL+P L R D + +PKG +V Sbjct: 347 YDALAQMEYLDMVVNETLRLYPIAARLERACKKDVEI-----HGVFVPKGTVVVVPVFVL 401 Query: 508 NRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHL 329 +R P ++ P+ + P+RF+ ++ ++Y+ FG G C+G FA + +K + Sbjct: 402 HRDPDLWPEPEEFRPERFS--KKHKDTINPYTYLPFGTGPRNCIGMRFALMNMKLALVRV 459 Query: 328 LRNFEFE 308 L+NF F+ Sbjct: 460 LQNFSFK 466
>CP4A5_RABIT (P14579) Cytochrome P450 4A5 precursor (EC 1.14.15.3) (CYPIVA5)| (Lauric acid omega-hydroxylase) Length = 511 Score = 62.8 bits (151), Expect = 1e-09 Identities = 39/122 (31%), Positives = 61/122 (50%) Frame = -3 Query: 679 LAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 500 L +M CIK A+RL+PP+ + R S VT +G+ +PKG V S + Sbjct: 367 LDQMPYTTMCIKEAMRLYPPVPAISRDLSSP--VTFPDGRS--LPKGFTVTLSIYGLHHN 422 Query: 499 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 320 P+++ NP+ +DP RF G + +++ F GG C+G+ FA ++K L Sbjct: 423 PNVWPNPEVFDPGRFTPG----SARHSHAFLPFSGGARNCIGKQFAMNELKVAVALTLVR 478 Query: 319 FE 314 FE Sbjct: 479 FE 480
>CP4AB_HUMAN (Q02928) Cytochrome P450 4A11 precursor (EC 1.14.15.3) (CYPIVA11)| (Fatty acid omega-hydroxylase) (P-450 HK omega) (Lauric acid omega-hydroxylase) (CYP4AII) (P450-HL-omega) Length = 519 Score = 62.8 bits (151), Expect = 1e-09 Identities = 40/122 (32%), Positives = 64/122 (52%) Frame = -3 Query: 679 LAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 500 L +M CIK ALRL+PP+ + R+ + VT +G+ +PKG +V S + Sbjct: 366 LDQMPYTTMCIKEALRLYPPVPGIGRELSTP--VTFPDGRS--LPKGIMVLLSIYGLHHN 421 Query: 499 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 320 P ++ NP+ +DP RFA G + + +++ F GG C+G+ FA ++K L Sbjct: 422 PKVWPNPEVFDPFRFAPGSAQH----SHAFLPFSGGSRNCIGKQFAMNELKVATALTLLR 477 Query: 319 FE 314 FE Sbjct: 478 FE 479
>CP11A_CAPHI (P79153) Cytochrome P450 11A1, mitochondrial precursor (EC| 1.14.15.6) (CYPXIA1) (P450(scc)) (Cholesterol side-chain cleavage enzyme) (Cholesterol desmolase) Length = 520 Score = 62.4 bits (150), Expect = 1e-09 Identities = 40/126 (31%), Positives = 63/126 (50%) Frame = -3 Query: 682 ILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANR 503 +L + +L IK LRLHP + L R SD + +++ IP +V + R Sbjct: 369 MLQMVPLLKASIKETLRLHPISVTLQRYPESDLVL-----QDYLIPAKTLVQVAIYAMGR 423 Query: 502 LPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLR 323 P F NPD +DP R+ G+++D + F + FG G C+G A L++ H+L Sbjct: 424 DPAFFSNPDKFDPTRWL-GKDKDLIH--FRNLGFGWGVRQCVGRRIAELEMTLFLIHILE 480 Query: 322 NFEFEL 305 NF+ E+ Sbjct: 481 NFKIEM 486
>CP26A_XENLA (O93323) Cytochrome P450 26A1 (EC 1.14.-.-) (Retinoic acid| degrading enzyme CYP26) (xCYP26) (Retinoic acid-converting enzyme) (RACE) Length = 492 Score = 62.4 bits (150), Expect = 1e-09 Identities = 41/132 (31%), Positives = 64/132 (48%) Frame = -3 Query: 685 DILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFAN 506 ++L ++ IK LRL PP+ R + F + + IPKG V S A + Sbjct: 343 EVLQQLKYTSCVIKETLRLSPPVAGGFRVALKTFVLNG-----YQIPKGWNVIYSIADTH 397 Query: 505 RLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLL 326 +F + D ++PDRF D + F +I FGGG C+G+ FA + +K L Sbjct: 398 GEADLFPDTDKFNPDRFLTPLPRD--SSRFGFIPFGGGVRCCIGKEFAKILLKVFVVELC 455 Query: 325 RNFEFELVSPFP 290 RN ++EL++ P Sbjct: 456 RNCDWELLNGSP 467
>CP39A_MOUSE (Q9JKJ9) Cytochrome P450 39A1 (EC 1.14.13.99)| (24-hydroxycholesterol 7-alpha-hydroxylase) (Oxysterol 7-alpha-hydroxylase) (mCYP39A1) Length = 470 Score = 62.4 bits (150), Expect = 1e-09 Identities = 43/161 (26%), Positives = 79/161 (49%), Gaps = 3/161 (1%) Frame = -3 Query: 697 KIDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSP 518 K+ D L ++ ++ CI ++RL P ++ + V + +P G ++ SP Sbjct: 317 KVSEDDLKKLLIIKWCILESVRLRAPGVITRKV------VKPVKILNHTVPSGDLLMLSP 370 Query: 517 AFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIW 338 + +R P F P+S+ P+R+ DK +++FGGG+ C G FA L+I+ Sbjct: 371 FWLHRNPKYFPEPESFKPERWKEANL-DKYIFLDYFMAFGGGKFQCPGRWFALLEIQLCI 429 Query: 337 THLLRNFEFELVSPFPENDWNAMVVGI---KGEVMVNYKRR 224 +L +E L+ P P+ + +VG+ G+ + YK+R Sbjct: 430 ILVLYKYECSLLDPLPKQS-SRHLVGVPQPAGKCRIEYKQR 469
>CP4A6_RABIT (P14580) Cytochrome P450 4A6 precursor (EC 1.14.15.3) (CYPIVA6)| (Lauric acid omega-hydroxylase) (P450-KA-1) Length = 510 Score = 62.4 bits (150), Expect = 1e-09 Identities = 50/154 (32%), Positives = 75/154 (48%) Frame = -3 Query: 679 LAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 500 L +M CIK ALRL+PP+ + RQ S VT +G+ +PKG IV S + Sbjct: 366 LDQMPYTTMCIKEALRLYPPVPGVGRQLSSP--VTFPDGRS--LPKGVIVTLSIYALHHN 421 Query: 499 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 320 P ++ NP+ +DP FA G + +++ F GG C+G+ FA ++K L Sbjct: 422 PKVWPNPEVFDPFPFAPG----SARHSHAFLPFSGGPRNCIGKQFAMNELKVAVALTLVR 477 Query: 319 FEFELVSPFPENDWNAMVVGIKGEVMVNYKRRKL 218 FE L P D +V +K ++ + RKL Sbjct: 478 FEL-LPDPKRVPDQKPRLV-LKSSNGIHLRLRKL 509
>CP26B_BRARE (Q6EIG3) Cytochrome P450 26B1 (EC 1.14.-.-) (Cyp26B1)| (Retinoic-acid metabolizing cytochrome) Length = 511 Score = 62.0 bits (149), Expect = 2e-09 Identities = 43/127 (33%), Positives = 63/127 (49%) Frame = -3 Query: 685 DILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFAN 506 D + + L IK LRL P+ R + F + +G + +PKG V S + Sbjct: 345 DSIISLKYLDCVIKEVLRLFAPVSGGYRIATQTFEL---DGVQ--VPKGWSVMYSIRDTH 399 Query: 505 RLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLL 326 +FK+ +++DPDRF+ R ED+ G F Y+ FGGG CLG+ A L +K + L Sbjct: 400 DTSAVFKDVEAFDPDRFSPERSEDR-EGRFHYLPFGGGVRSCLGKQLATLFLKLLAVELA 458 Query: 325 RNFEFEL 305 FEL Sbjct: 459 GGSRFEL 465
>CP46A_MOUSE (Q9WVK8) Cytochrome p450 46A1 (EC 1.14.13.98) (Cholesterol| 24-hydroxylase) (CH24H) Length = 500 Score = 62.0 bits (149), Expect = 2e-09 Identities = 37/131 (28%), Positives = 65/131 (49%) Frame = -3 Query: 694 IDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPA 515 +D++ L + L + +K +LRL+PP R + T +G +P + S Sbjct: 342 LDYEDLGRLQYLSQVLKESLRLYPPAWGTFRLLEEE---TLIDGVR--VPGNTPLLFSTY 396 Query: 514 FANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWT 335 R+ F++P +++PDRF G + + F+Y F G C+G+ FA +++K + Sbjct: 397 VMGRMDTYFEDPLTFNPDRFGPGAPKPR----FTYFPFSLGHRSCIGQQFAQMEVKVVMA 452 Query: 334 HLLRNFEFELV 302 LL+ EF LV Sbjct: 453 KLLQRIEFRLV 463
>CP4F8_HUMAN (P98187) Cytochrome P450 4F8 (EC 1.14.14.1) (CYPIVF8)| Length = 520 Score = 61.6 bits (148), Expect = 2e-09 Identities = 37/127 (29%), Positives = 61/127 (48%) Frame = -3 Query: 697 KIDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSP 518 +I+ D LA++ L C+K +LRLHPP+ R D + IPKG++ + Sbjct: 369 EIEWDDLAQLPFLTMCLKESLRLHPPIPTFARGCTQDVVLPDSR----VIPKGNVCNINI 424 Query: 517 AFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIW 338 + P ++ +P+ YDP RF E + ++I F G C+G+ FA ++K + Sbjct: 425 FAIHHNPSVWPDPEVYDPFRF--DPENAQKRSPMAFIPFSAGPRNCIGQKFAMAEMKVVL 482 Query: 337 THLLRNF 317 L F Sbjct: 483 ALTLLRF 489
>CP11A_SHEEP (P79202) Cytochrome P450 11A1, mitochondrial precursor (EC| 1.14.15.6) (CYPXIA1) (P450(SCC)) (Cholesterol side-chain cleavage enzyme) (Cholesterol desmolase) Length = 520 Score = 61.6 bits (148), Expect = 2e-09 Identities = 40/126 (31%), Positives = 62/126 (49%) Frame = -3 Query: 682 ILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANR 503 +L + +L IK LRLHP + L R SD + +++ IP +V + R Sbjct: 369 MLQMVPLLKASIKETLRLHPISVTLQRYPESDLVL-----QDYLIPAKTLVQVAIYAMGR 423 Query: 502 LPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLR 323 P F NPD +DP R+ G+++D + F + FG G C+G A L++ H+L Sbjct: 424 DPAFFSNPDKFDPTRWL-GKDKDLIH--FRNLGFGWGVRQCVGRRIAELEMTLFLIHILE 480 Query: 322 NFEFEL 305 NF E+ Sbjct: 481 NFRVEM 486
>CP3AO_SHEEP (Q29496) Cytochrome P450 3A24 (EC 1.14.14.1) (CYPIIIA24)| Length = 503 Score = 61.6 bits (148), Expect = 2e-09 Identities = 36/127 (28%), Positives = 62/127 (48%) Frame = -3 Query: 688 HDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFA 509 +D+LA+M+ L + LR+ P + L R D + IPKG V Sbjct: 347 YDVLAQMEYLDMVVNETLRMFPIAVRLDRLCKKDVEI-----HGVSIPKGTAVTVPIFVL 401 Query: 508 NRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHL 329 +R P ++ P+ + P+RF+ + +D + + Y+ FG G C+G FA + +K + Sbjct: 402 HRDPQLWPEPEEFRPERFSK-KNKDSI-NPYVYLPFGTGPRNCIGMRFAIMNMKLAIVRV 459 Query: 328 LRNFEFE 308 L+NF F+ Sbjct: 460 LQNFSFK 466
>CP4A7_RABIT (P14581) Cytochrome P450 4A7 precursor (EC 1.14.15.3) (CYPIVA7)| (Lauric acid omega-hydroxylase) (P450-KA-2) Length = 511 Score = 61.2 bits (147), Expect = 3e-09 Identities = 40/122 (32%), Positives = 62/122 (50%) Frame = -3 Query: 679 LAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 500 L +M CIK ALRL+PP+ + + S VT +G+ +PKG I+ S + Sbjct: 367 LDKMPYTTMCIKEALRLYPPVPGVGSKLSSP--VTFPDGRS--LPKGIIITLSIYGLHHN 422 Query: 499 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 320 P ++ NP+ +DP RFA G + +++ F GG C+G+ FA ++K L Sbjct: 423 PKVWPNPEVFDPSRFAPG----SARHSHAFLPFSGGSRNCIGKQFAMNELKVAVALTLVR 478 Query: 319 FE 314 FE Sbjct: 479 FE 480
>CP3A6_RABIT (P11707) Cytochrome P450 3A6 (EC 1.14.14.1) (CYPIIIA6) (P450-3C)| Length = 501 Score = 61.2 bits (147), Expect = 3e-09 Identities = 40/128 (31%), Positives = 59/128 (46%) Frame = -3 Query: 688 HDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFA 509 +D L +M+ L + LRL+P L R D + IPKG IV Sbjct: 345 YDTLVKMEYLDMVVNETLRLYPIAGRLERVCKKDVDINGTF-----IPKGTIVMMPTYAL 399 Query: 508 NRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHL 329 +R P + PD + P+RF+ +++ + Y FG G CLG FA + IK L Sbjct: 400 HRDPQHWTEPDEFRPERFSKKNKDN--INPYIYHPFGAGPRNCLGMRFALMNIKLALVRL 457 Query: 328 LRNFEFEL 305 ++NF F+L Sbjct: 458 MQNFSFKL 465
>CP4S3_DROME (Q9VXY0) Probable cytochrome P450 4s3 (EC 1.14.-.-) (CYPIVS3)| Length = 495 Score = 61.2 bits (147), Expect = 3e-09 Identities = 38/120 (31%), Positives = 59/120 (49%) Frame = -3 Query: 670 MDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRLPHI 491 M L IK LR++P + R+ D V GK +PKG ++ +R P Sbjct: 348 MPYLEAVIKETLRIYPSVPFFSRKVLEDLEV----GK-LTVPKGASISCLIYMLHRDPKN 402 Query: 490 FKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEF 311 F +P+ +DPDRF +K F++ +F G C+G+ FA L++K LLR++ F Sbjct: 403 FPDPERFDPDRFLVN---EKQMHPFAFAAFSAGPRNCIGQKFAMLELKTSLAMLLRSYRF 459
>CP3A9_RAT (P51538) Cytochrome P450 3A9 (EC 1.14.14.1) (CYPIIIA9) (P450-OLF3)| (Olfactive) (3AH15) Length = 503 Score = 61.2 bits (147), Expect = 3e-09 Identities = 35/127 (27%), Positives = 61/127 (48%) Frame = -3 Query: 688 HDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFA 509 +D L +M+ L + LRL+P L R +D + IPKG +V Sbjct: 347 YDTLLQMEYLDMVVNETLRLYPIAGRLERVCKTDVEING-----VFIPKGTVVMIPTFAL 401 Query: 508 NRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHL 329 ++ PH + P+ + P+RF+ +++ + Y+ FG G C+G FA + +K + Sbjct: 402 HKDPHYWPEPEEFRPERFSKKNQDN--INPYMYLPFGNGPRNCIGMRFALMNMKVALFRV 459 Query: 328 LRNFEFE 308 L+NF F+ Sbjct: 460 LQNFSFQ 466
>C28A5_DROME (Q9V419) Probable cytochrome P450 28a5 (EC 1.14.-.-) (CYPXXVIIIA5)| Length = 505 Score = 61.2 bits (147), Expect = 3e-09 Identities = 40/155 (25%), Positives = 71/155 (45%), Gaps = 4/155 (2%) Frame = -3 Query: 679 LAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 500 L+++ L C++ +RL PP M + + +EG F + KG V P + L Sbjct: 351 LSDLPYLDACVQETIRLFPPGFMSNKLCTESIEIPNKEGPNFVVEKGTTVVV-PHYCFML 409 Query: 499 -PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLR 323 F NP S+ P+RF ++ FG G C+G FA +QIKA L+ Sbjct: 410 DEEFFPNPQSFQPERFLEPDAAKTFRERGVFMGFGDGPRVCIGMRFATVQIKAAIVELIS 469 Query: 322 NFEFELVSPF-PENDW--NAMVVGIKGEVMVNYKR 227 F ++ +ND+ ++ G++G + ++ ++ Sbjct: 470 KFNVKINDKTRKDNDYEPGQIITGLRGGIWLDLEK 504
>C76A1_SOLME (P37121) Cytochrome P450 76A1 (EC 1.14.-.-) (CYPLXXVIA1) (P-450EG8)| (Fragment) Length = 467 Score = 60.8 bits (146), Expect = 4e-09 Identities = 43/138 (31%), Positives = 67/138 (48%), Gaps = 3/138 (2%) Frame = -3 Query: 700 DKIDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATS 521 ++ D D L M + +K LRLHPPL +L+ + ++ + +DIPKG V + Sbjct: 312 EECDIDSLPYMQAV---LKEQLRLHPPLPLLIPRK----AIQDTKFMGYDIPKGTQVLVN 364 Query: 520 PAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAI 341 R P + NP + P+RF + + K + I FG GR C+G P + + Sbjct: 365 AWAIGRDPEYWDNPFEFKPERFLESKVDVKGQN-YELIPFGAGRRMCVGLPLGHRMMHFT 423 Query: 340 WTHLLRNFEFEL---VSP 296 + LL F++EL VSP Sbjct: 424 FGSLLHEFDWELPHNVSP 441
>CP46A_HUMAN (Q9Y6A2) Cytochrome p450 46A1 (EC 1.14.13.98) (Cholesterol| 24-hydroxylase) (CH24H) Length = 500 Score = 60.8 bits (146), Expect = 4e-09 Identities = 37/131 (28%), Positives = 64/131 (48%) Frame = -3 Query: 694 IDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPA 515 +D + L + L + +K +LRL+PP R + T +G +P + S Sbjct: 342 LDFEDLGRLQYLSQVLKESLRLYPPAWGTFRLLEEE---TLIDGVR--VPGNTPLLFSTY 396 Query: 514 FANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWT 335 R+ F++P +++PDRF G + + F+Y F G C+G+ FA +++K + Sbjct: 397 VMGRMDTYFEDPLTFNPDRFGPGAPKPR----FTYFPFSLGHRSCIGQQFAQMEVKVVMA 452 Query: 334 HLLRNFEFELV 302 LL+ EF LV Sbjct: 453 KLLQRLEFRLV 463
>CP6D4_DROME (Q9VCW1) Probable cytochrome P450 6d4 (EC 1.14.-.-) (CYPVID4)| Length = 515 Score = 60.8 bits (146), Expect = 4e-09 Identities = 39/133 (29%), Positives = 67/133 (50%) Frame = -3 Query: 697 KIDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSP 518 KI +D L +M+ L C++ +R +P L +L R+ D++V IPKG V S Sbjct: 358 KITYDSLNKMEFLDLCVQETIRKYPGLPILNRECTQDYTVPDTNHV---IPKGTPVVISL 414 Query: 517 AFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIW 338 + F +P++YDP+RF+ EE + +++ FG G C+ + + K Sbjct: 415 YGIHHDAEYFPDPETYDPERFS---EESRNYNPTAFMPFGEGPRICIAQRMGRINSKLAI 471 Query: 337 THLLRNFEFELVS 299 +L+NF E++S Sbjct: 472 IKILQNFNVEVMS 484
>CP3AH_CAVPO (Q64409) Cytochrome P450 3A17 (EC 1.14.14.1) (CYPIIIA17)| Length = 503 Score = 60.8 bits (146), Expect = 4e-09 Identities = 41/127 (32%), Positives = 63/127 (49%), Gaps = 1/127 (0%) Frame = -3 Query: 688 HDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFA 509 +D++ EM+ L + LRL+P + R S DF + G F PKG V P+FA Sbjct: 347 YDVMMEMEYLDMVVNETLRLYPVTNRIERMSKKDFEIN---GMSF--PKGTGVMI-PSFA 400 Query: 508 -NRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTH 332 +R + PD + P+RF+ +E+ + Y+ FG G C+G A + +K Sbjct: 401 LHRDSKYWPEPDEFRPERFSKKNKEN--IDPYIYMPFGNGPRNCIGMRMALMNLKLALIR 458 Query: 331 LLRNFEF 311 LL+NF F Sbjct: 459 LLQNFSF 465
>CP3AE_CAVPO (Q64417) Cytochrome P450 3A14 (EC 1.14.14.1) (CYPIIIA14)| Length = 503 Score = 60.8 bits (146), Expect = 4e-09 Identities = 41/127 (32%), Positives = 63/127 (49%), Gaps = 1/127 (0%) Frame = -3 Query: 688 HDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFA 509 +D++ EM+ L + LRL+P + R S DF + G F PKG V P+FA Sbjct: 347 YDVMMEMEYLDMVVNETLRLYPVTNRIERMSKKDFEIN---GMSF--PKGTGVMI-PSFA 400 Query: 508 -NRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTH 332 +R + PD + P+RF+ +E+ + Y+ FG G C+G A + +K Sbjct: 401 LHRDSKYWPEPDEFRPERFSKKNKEN--IDPYIYMPFGNGPRNCIGMRMALMNLKLALIR 458 Query: 331 LLRNFEF 311 LL+NF F Sbjct: 459 LLQNFSF 465
>CP120_SYNY3 (Q59990) Putative cytochrome P450 120 (EC 1.14.-.-)| Length = 444 Score = 60.8 bits (146), Expect = 4e-09 Identities = 37/128 (28%), Positives = 66/128 (51%) Frame = -3 Query: 685 DILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFAN 506 + L +M L + ++ LRL PP+ R+ D + F PKG +V+ + + Sbjct: 296 ETLKKMPYLDQVLQEVLRLIPPVGGGFRELIQDCQF-----QGFHFPKGWLVSYQISQTH 350 Query: 505 RLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLL 326 P ++ +P+ +DP+RF F+++ FGGG CLG+ FA L++K T L+ Sbjct: 351 ADPDLYPDPEKFDPERFTPDGSATHNP-PFAHVPFGGGLRECLGKEFARLEMKLFATRLI 409 Query: 325 RNFEFELV 302 + F++ L+ Sbjct: 410 QQFDWTLL 417
>CP4B1_MOUSE (Q64462) Cytochrome P450 4B1 (EC 1.14.14.1) (CYPIVB1)| Length = 511 Score = 60.5 bits (145), Expect = 5e-09 Identities = 41/137 (29%), Positives = 67/137 (48%) Frame = -3 Query: 700 DKIDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATS 521 D D LA+M L C+K RL+PP+ + RQ VT +G+ +P G +++ Sbjct: 353 DSFQWDDLAQMTYLTMCMKECFRLYPPVPQVYRQLSKP--VTFVDGRS--LPAGSLISLH 408 Query: 520 PAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAI 341 +R ++ +P+ +DP RF+ E F+++ F G C+G+ FA ++K + Sbjct: 409 IYALHRNSAVWPDPEVFDPLRFSP--ENMTGRHPFAFMPFSAGPRNCIGQQFAMNEMKVV 466 Query: 340 WTHLLRNFEFELVSPFP 290 L FEF SP P Sbjct: 467 TALCLLRFEF---SPDP 480
>C77A2_SOLME (P37124) Cytochrome P450 77A2 (EC 1.14.-.-) (CYPLXXVIIA2)| (P-450EG5) Length = 511 Score = 60.5 bits (145), Expect = 5e-09 Identities = 41/132 (31%), Positives = 63/132 (47%), Gaps = 2/132 (1%) Frame = -3 Query: 700 DKIDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATS 521 +KID + +M L +K LR HPP M L +H+ G +DIP G V Sbjct: 352 NKIDEKDIEKMPYLNAVVKELLRKHPPTYMSL--THAVTEPAKLGG--YDIPTGVNVEIF 407 Query: 520 PAFANRLPHIFKNPDSYDPDRFAAGREEDKVAG--AFSYISFGGGRHGCLGEPFAYLQIK 347 + P+++ P+ +DPDRF G+E+ + G I FG GR C G A + + Sbjct: 408 LPGISDDPNLWSEPEKFDPDRFYLGKEDADITGVSGVKMIPFGMGRRICPGLNMATVHVS 467 Query: 346 AIWTHLLRNFEF 311 + L++ FE+ Sbjct: 468 LMLARLVQEFEW 479
>C71B3_ARATH (O65785) Cytochrome P450 71B3 (EC 1.14.-.-)| Length = 501 Score = 60.5 bits (145), Expect = 5e-09 Identities = 38/133 (28%), Positives = 69/133 (51%), Gaps = 1/133 (0%) Frame = -3 Query: 700 DKIDHDILAEMDVLYRCIKXALRLHPPLIMLL-RQSHSDFSVTTREGKEFDIPKGHIVAT 524 ++I+ + + ++ L IK LRLHPP +LL R++ +D + + +DIP+ I+ Sbjct: 344 ERIEEEDVDKLQYLKLVIKETLRLHPPAPLLLPRETMADIKI-----QGYDIPRKTILLV 398 Query: 523 SPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKA 344 + R P +++NP+ ++P+RF D +F + FG GR C G F ++ Sbjct: 399 NAWSIGRNPELWENPEEFNPERF-IDCPMDYKGNSFEMLPFGSGRKICPGIAFGIATVEL 457 Query: 343 IWTHLLRNFEFEL 305 +LL F++ L Sbjct: 458 GLLNLLYYFDWRL 470
>CP6B2_HELAM (Q27664) Cytochrome P450 6B2 (EC 1.14.14.1) (CYPVIB2)| Length = 504 Score = 60.5 bits (145), Expect = 5e-09 Identities = 48/165 (29%), Positives = 74/165 (44%), Gaps = 6/165 (3%) Frame = -3 Query: 697 KIDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSP 518 K+ +D + +M L + LR++ + L R++ D+ + G + I K +V SP Sbjct: 345 KVTYDTVKDMKYLNKVFDETLRMYSIVEPLQRKAIRDYKLP---GTDVVIEKDTVVLISP 401 Query: 517 AFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIW 338 + P + NP ++P+RF A EE +Y+ FG G+ C+G F LQ Sbjct: 402 RGIHYDPKYYDNPKQFNPERFFA--EEVGKRHPCAYLPFGLGQRNCIGMRFGRLQSLLCI 459 Query: 337 THLLRNFEFELVSPFPENDWNAMV------VGIKGEVMVNYKRRK 221 T LL F E P D N V +G KG + +N RK Sbjct: 460 TKLLSKFRLE---PSKNTDRNLQVEPYRFIIGPKGGIRLNIVPRK 501
>CP11A_MESAU (Q9EPT4) Cytochrome P450 11A1, mitochondrial precursor (EC| 1.14.15.6) (CYPXIA1) (P450(scc)) (Cholesterol side-chain cleavage enzyme) (Cholesterol desmolase) Length = 520 Score = 60.5 bits (145), Expect = 5e-09 Identities = 40/122 (32%), Positives = 57/122 (46%) Frame = -3 Query: 664 VLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRLPHIFK 485 +L IK LRLHP + + R D + + + IP +V + R P F Sbjct: 372 LLKASIKETLRLHPISVTVQRYLVDDLVL-----RNYRIPAKMLVQVANYAMGREPSFFP 426 Query: 484 NPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL 305 NP+ +DP R+ E+ K F Y+SFG G CLG A L++ ++L NF EL Sbjct: 427 NPNKFDPTRWL---EKSKNTTHFRYLSFGWGVRQCLGRRIAELEMTIFLINVLENFRIEL 483 Query: 304 VS 299 S Sbjct: 484 QS 485
>C76A2_SOLME (P37122) Cytochrome P450 76A2 (EC 1.14.-.-) (CYPLXXVIA2) (P-450EG7)| Length = 505 Score = 60.5 bits (145), Expect = 5e-09 Identities = 41/137 (29%), Positives = 65/137 (47%), Gaps = 3/137 (2%) Frame = -3 Query: 697 KIDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSP 518 K + + + + +K +LRLHPPL L+ + ++ + +D+PK V + Sbjct: 348 KFEDSDIENLPYMQAVLKESLRLHPPLPFLIPRE----TIQDTKFMGYDVPKDTQVLVNA 403 Query: 517 AFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIW 338 R P + +P S+ P+RF G + D + I FG GR C+G P + + Sbjct: 404 WAIGRDPECWDDPMSFKPERFL-GSKIDVKGQHYGLIPFGAGRRMCVGLPLGHRMMHFAL 462 Query: 337 THLLRNFEFEL---VSP 296 LLR FE+EL VSP Sbjct: 463 GSLLREFEWELPDGVSP 479
>CP4AC_RAT (P24464) Cytochrome P450 4A12 (EC 1.14.14.1) (CYPIVA12) (CYPIVA8)| (P450-KP1) (P450-PP1) Length = 508 Score = 60.5 bits (145), Expect = 5e-09 Identities = 41/127 (32%), Positives = 63/127 (49%) Frame = -3 Query: 694 IDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPA 515 I D L +M CIK ALR++PP+ + R + VT +G+ +PKG V S Sbjct: 359 ITWDDLDKMPYTTMCIKEALRIYPPVTAVSRMLSTP--VTFPDGRS--LPKGITVMLSFY 414 Query: 514 FANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWT 335 + P ++ NP+ +DP RFA + + S++ F GG C+G+ FA ++K Sbjct: 415 GLHHNPTVWPNPEVFDPYRFAP----ESSRHSHSFLPFSGGARNCIGKQFAMNELKVAVA 470 Query: 334 HLLRNFE 314 L FE Sbjct: 471 LTLLRFE 477
>CP3AR_ONCMY (O42563) Cytochrome P450 3A27 (EC 1.14.14.1) (CYPIIIA27)| Length = 518 Score = 60.5 bits (145), Expect = 5e-09 Identities = 39/130 (30%), Positives = 64/130 (49%) Frame = -3 Query: 694 IDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPA 515 I ++ L +MD L + +LRL+P L R + T E IPK IV Sbjct: 350 IQYEALMQMDYLDCVLNESLRLYPIAPRLERVAKK-----TVEINGIVIPKDCIVLVPTW 404 Query: 514 FANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWT 335 +R P I+ +P+ + P+RF+ +E + ++Y+ FG G C+G FA + IK Sbjct: 405 TLHRDPEIWSDPEEFKPERFS--KENKESIDPYTYMPFGAGPRNCIGMRFALIMIKLAMV 462 Query: 334 HLLRNFEFEL 305 +L++F F + Sbjct: 463 EILQSFTFSV 472
>C71BP_ARATH (Q9LTL2) Cytochrome P450 71B25 (EC 1.14.-.-)| Length = 501 Score = 60.1 bits (144), Expect = 6e-09 Identities = 39/133 (29%), Positives = 69/133 (51%), Gaps = 1/133 (0%) Frame = -3 Query: 700 DKIDHDILAEMDVLYRCIKXALRLHPPLIMLL-RQSHSDFSVTTREGKEFDIPKGHIVAT 524 ++I+ + + ++ L IK LRLHP +LL R++ +D + + +DIP+ ++ Sbjct: 344 ERIEEEDVGKLQYLKLVIKETLRLHPAAPLLLPRETMADIKI-----QGYDIPRKTLLLV 398 Query: 523 SPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKA 344 S R P +KNP+ ++P+RF D +F ++ FG GR C G A I+ Sbjct: 399 SAWSLGRDPKYWKNPEEFNPERF-IDCPVDYKGHSFEFLPFGSGRRFCPGMASAIATIEL 457 Query: 343 IWTHLLRNFEFEL 305 +LL F+++L Sbjct: 458 TLLNLLYFFDWKL 470
>C28D2_DROME (Q9VMT6) Probable cytochrome P450 28d2 (EC 1.14.-.-) (CYPXXVIIID2)| Length = 501 Score = 60.1 bits (144), Expect = 6e-09 Identities = 42/160 (26%), Positives = 73/160 (45%), Gaps = 8/160 (5%) Frame = -3 Query: 685 DILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFAN 506 D ++E+ L CI LRL P + + F + G+ + G +V + Sbjct: 343 DQMSELPHLDACIYETLRLFSPQVAARKLVTEPFEFANKNGRTVHLKPGDVVTIPVKALH 402 Query: 505 RLPHIFKNPDSYDPDRF----AAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIW 338 P +++P ++ P+RF G + + G Y++FG G C G FA Q+KA Sbjct: 403 HDPQYYEDPLTFKPERFLESNGGGMKSYRDRGV--YLAFGDGPRHCPGMRFALTQLKAAL 460 Query: 337 THLLRNFEFELVSPFPENDWNA----MVVGIKGEVMVNYK 230 +LRNFE + V+P +D + +KG + +++K Sbjct: 461 VEILRNFEIK-VNPKTRSDNQIDDTFFMATLKGGIYLDFK 499
>CP11A_MOUSE (Q9QZ82) Cytochrome P450 11A1, mitochondrial precursor (EC| 1.14.15.6) (CYPXIA1) (P450(scc)) (Cholesterol side-chain cleavage enzyme) (Cholesterol desmolase) Length = 526 Score = 60.1 bits (144), Expect = 6e-09 Identities = 38/120 (31%), Positives = 58/120 (48%) Frame = -3 Query: 664 VLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRLPHIFK 485 +L IK LRLHP + L R + +D + + + IP +V + R P F Sbjct: 372 LLKASIKETLRLHPISVTLQRYTVNDLVL-----RNYKIPAKTLVQVASFAMGRDPGFFP 426 Query: 484 NPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL 305 NP+ +DP R+ E+ + F Y+ FG G CLG A L++ + +LL NF E+ Sbjct: 427 NPNKFDPTRWL---EKSQNTTHFRYLGFGWGVRQCLGRRIAELEMTILLINLLENFRIEV 483
>C77A1_SOLME (P37123) Cytochrome P450 77A1 (EC 1.14.-.-) (CYPLXXVIIA1)| (P-450EG6) (Fragment) Length = 499 Score = 59.7 bits (143), Expect = 8e-09 Identities = 38/131 (29%), Positives = 63/131 (48%), Gaps = 2/131 (1%) Frame = -3 Query: 697 KIDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSP 518 K+D + + +M L +K LR HPP L +HS G +DIP V Sbjct: 340 KVDENDIEKMPYLNAVVKELLRKHPPTYFTL--THSVTEPVKLAG--YDIPMDTNVEFFV 395 Query: 517 AFANRLPHIFKNPDSYDPDRFAAGREEDKVAGA--FSYISFGGGRHGCLGEPFAYLQIKA 344 + P+++ +P+ +DPDRF +GRE+ + G + FG GR C G A + + Sbjct: 396 HGISHDPNVWSDPEKFDPDRFLSGREDADITGVKEVKMMPFGVGRRICPGLGMATVHVNL 455 Query: 343 IWTHLLRNFEF 311 + +++ FE+ Sbjct: 456 MLARMVQEFEW 466
>C4D21_DROME (Q9VLZ7) Probable cytochrome P450 4d21 (EC 1.14.-.-) (CYPIVD21)| Length = 511 Score = 59.7 bits (143), Expect = 8e-09 Identities = 37/122 (30%), Positives = 59/122 (48%) Frame = -3 Query: 679 LAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 500 L E+ L IK +RLHPP+ +L R D + E IP + P + R Sbjct: 363 LLELKYLDCVIKETMRLHPPVPILGRYIPEDLKIG-----EITIPGNTSILLMPYYVYRD 417 Query: 499 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 320 P F +P + P+R+ + +YI F G C+G+ FA LQ+KA+ + ++R+ Sbjct: 418 PEYFPDPLVFKPERWMDMKTTSNTP-PLAYIPFSSGPKNCIGQKFANLQMKALISKVIRH 476 Query: 319 FE 314 +E Sbjct: 477 YE 478
>CP131_DROME (Q9VFJ0) Probable cytochrome P450 313a1 (EC 1.14.-.-)| (CYPCCCXIIIA1) Length = 492 Score = 59.7 bits (143), Expect = 8e-09 Identities = 37/128 (28%), Positives = 64/128 (50%), Gaps = 1/128 (0%) Frame = -3 Query: 694 IDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPA 515 I + + ++D L R IK LRL P + + R++ +D R IPKG ++ Sbjct: 339 ITYPDMQKLDYLERVIKETLRLIPAIPITARETKND----VRLSNGVLIPKGVVIGIDMF 394 Query: 514 FANRLPHIF-KNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIW 338 +R P ++ + D+++PD F A E K ++YI F G+ C+G +A + K Sbjct: 395 HTHRNPEVWGPDADNFNPDNFLAENMEQK--HPYAYIPFARGKRNCIGSKYAMMSSKFAL 452 Query: 337 THLLRNFE 314 +LRN++ Sbjct: 453 CRILRNYK 460
>C98A1_SORBI (O48956) Cytochrome P450 98A1 (EC 1.14.-.-)| Length = 512 Score = 59.7 bits (143), Expect = 8e-09 Identities = 43/132 (32%), Positives = 61/132 (46%), Gaps = 1/132 (0%) Frame = -3 Query: 661 LYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRLPHIFKN 482 L +K +LRLHPP ++L S T + +DIPKG V + R P ++ N Sbjct: 353 LQAVVKESLRLHPPTPLMLPHKAS----TNVKIGGYDIPKGANVMVNVWAVARDPKVWSN 408 Query: 481 PDSYDPDRFAAGREEDKVAGA-FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL 305 P Y P+RF E + G+ F + FG GR C G + ++ HLL +FE+ L Sbjct: 409 PLEYRPERFL--EENIDIKGSDFRVLPFGAGRRVCPGAQLGINLVASMIGHLLHHFEWSL 466 Query: 304 VSPFPENDWNAM 269 D N M Sbjct: 467 PEGTRPEDVNMM 478
>CP4E2_DROME (Q27606) Cytochrome P450 4e2 (EC 1.14.-.-) (CYPIVE2)| Length = 526 Score = 59.7 bits (143), Expect = 8e-09 Identities = 36/122 (29%), Positives = 62/122 (50%) Frame = -3 Query: 679 LAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 500 +++M L IK A R++P + + R + D+ + +G +PKG + Sbjct: 355 ISQMKYLDLFIKEAQRVYPSVPFIGRFTEKDYVI---DGDL--VPKGTTLNLGLVMLGYN 409 Query: 499 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 320 +FK+P + P+RF E + G F Y+ F G C+G+ FA L+IK + + ++RN Sbjct: 410 EKVFKDPHKFRPERF-----ELEKPGPFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRN 464 Query: 319 FE 314 FE Sbjct: 465 FE 466
>T10H_TAXCU (Q9AXM6) Taxane 10-beta-hydroxylase (EC 1.14.13.76)| (5-alpha-taxadienol-10-beta-hydroxylase) (Cytochrome P450 725A1) Length = 497 Score = 59.7 bits (143), Expect = 8e-09 Identities = 34/128 (26%), Positives = 62/128 (48%) Frame = -3 Query: 700 DKIDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATS 521 ++I L M ++ ++ +LR++PP+ + R++ +D + IPKG V S Sbjct: 345 EEISWKDLKSMKYTWQAVQESLRMYPPVFGIFRKAITDIHYDG-----YTIPKGWRVLCS 399 Query: 520 PAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAI 341 P + F P+ + P RF +E + ++Y+ FGGG C G F+ ++I Sbjct: 400 PYTTHLREEYFPEPEEFRPSRF---EDEGRHVTPYTYVPFGGGLRTCPGWEFSKIEILLF 456 Query: 340 WTHLLRNF 317 H ++NF Sbjct: 457 VHHFVKNF 464
>CP3AI_RAT (Q64581) Cytochrome P450 3A18 (EC 1.14.14.1) (CYPIIIA18)| (P450(6)beta-2) Length = 497 Score = 59.7 bits (143), Expect = 8e-09 Identities = 37/129 (28%), Positives = 61/129 (47%) Frame = -3 Query: 694 IDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPA 515 + +D L EM+ L + +LRL+P L R S D + IPKG +V Sbjct: 345 VTYDALMEMEYLDMVVNESLRLYPIATRLDRVSKKDVEING-----VFIPKGTVVTIPIY 399 Query: 514 FANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWT 335 +R P + P+ ++P+RF+ +E + Y+ FG G C+G FA + +K Sbjct: 400 PLHRNPEYWLEPEEFNPERFS--KENKGSIDPYVYLPFGNGPRNCIGMRFALISMKLAVI 457 Query: 334 HLLRNFEFE 308 +L+NF + Sbjct: 458 GVLQNFNIQ 466
>CP6U1_DROME (Q9V979) Probable cytochrome P450 6u1 (EC 1.14.-.-) (CYPVIU1)| Length = 488 Score = 59.7 bits (143), Expect = 8e-09 Identities = 40/129 (31%), Positives = 60/129 (46%) Frame = -3 Query: 697 KIDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSP 518 ++ + L E+ + + LRLH P LLR++ +F V G F I KG+ V Sbjct: 330 QVTPECLRELRYTKQVLNETLRLHTPHPFLLRRATKEFEVP---GSVFVIAKGNNVLIPT 386 Query: 517 AFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIW 338 A + P I++NP + P+RF + A AF + FG G GC+ FA Q+ Sbjct: 387 AAIHMDPGIYENPQRFYPERFEEQARRSRPAAAF--LPFGDGLRGCIAARFAEQQLLVGL 444 Query: 337 THLLRNFEF 311 LLR + Sbjct: 445 VALLRQHRY 453
>C11B1_SHEEP (P51663) Cytochrome P450 11B1, mitochondrial precursor (EC| 1.14.15.4) (CYPXIB1) (P450C11) (Steroid 11-beta-hydroxylase) Length = 503 Score = 59.7 bits (143), Expect = 8e-09 Identities = 38/125 (30%), Positives = 61/125 (48%) Frame = -3 Query: 673 EMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRLPH 494 E+ +L +K LRL+P I L RQ SD + + + IP G +V R P Sbjct: 361 ELPLLRAALKETLRLYPVGITLERQVSSDLVL-----QNYHIPAGTLVKVLLYSLGRNPA 415 Query: 493 IFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFE 314 +F P+SY P R+ + F +++FG G CLG A +++ + H+L+NF Sbjct: 416 VFARPESYHPQRWL---DRQGSGSRFPHLAFGFGMRQCLGRRVAEVEMLLLLHHVLKNFL 472 Query: 313 FELVS 299 E ++ Sbjct: 473 VETLA 477
>CP4B1_RABIT (P15128) Cytochrome P450 4B1 (EC 1.14.14.1) (CYPIVB1) (P450-isozyme| 5) Length = 506 Score = 59.7 bits (143), Expect = 8e-09 Identities = 36/132 (27%), Positives = 64/132 (48%) Frame = -3 Query: 700 DKIDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATS 521 D + LA+M L C+K RL+PP+ + RQ S +G+ +P G +++ Sbjct: 348 DSFQWEDLAKMTYLTMCMKECFRLYPPVPQVYRQLSKPVSFV--DGRS--LPAGSLISLH 403 Query: 520 PAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAI 341 +R ++ +P+ +DP RF+ E +++I F G C+G+ FA ++K + Sbjct: 404 IYALHRNSDVWPDPEVFDPLRFSP--ENSSGRHPYAFIPFSAGPRNCIGQQFAMNEMKVV 461 Query: 340 WTHLLRNFEFEL 305 L FEF + Sbjct: 462 TALCLLRFEFSV 473
>CP4B1_HUMAN (P13584) Cytochrome P450 4B1 (EC 1.14.14.1) (CYPIVB1) (P450-HP)| Length = 511 Score = 59.3 bits (142), Expect = 1e-08 Identities = 38/132 (28%), Positives = 64/132 (48%) Frame = -3 Query: 700 DKIDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATS 521 D D L +M L CIK + RL+PP+ + RQ VT +G+ +P G +++ Sbjct: 353 DFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKP--VTFVDGRS--LPAGSLISMH 408 Query: 520 PAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAI 341 +R ++ +P+ +D RF+ E F+++ F G C+G+ FA ++K + Sbjct: 409 IYALHRNSAVWPDPEVFDSLRFST--ENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVV 466 Query: 340 WTHLLRNFEFEL 305 L FEF L Sbjct: 467 TAMCLLRFEFSL 478
>CP3A2_RAT (P05183) Cytochrome P450 3A2 (EC 1.14.14.1) (CYPIIIA2) (P450-PCN2)| (P450/6-beta-A) (Testosterone 6-beta-hydroxylase) Length = 504 Score = 59.3 bits (142), Expect = 1e-08 Identities = 40/128 (31%), Positives = 63/128 (49%), Gaps = 1/128 (0%) Frame = -3 Query: 688 HDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFA 509 +DI+ EM+ L + LRL+P L R D + IPKG +V T P +A Sbjct: 348 YDIVMEMEYLDMVLNETLRLYPIGNRLERVCKKDIELDG-----LFIPKGSVV-TIPTYA 401 Query: 508 -NRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTH 332 + P + P+ + P+RF+ +E + Y+ FG G C+G FA + +K T Sbjct: 402 LHHDPQHWPKPEEFHPERFS--KENKGSIDPYVYLPFGNGPRNCIGMRFALMNMKLALTK 459 Query: 331 LLRNFEFE 308 +L+NF F+ Sbjct: 460 VLQNFSFQ 467
>CP11A_BOVIN (P00189) Cytochrome P450 11A1, mitochondrial precursor (EC| 1.14.15.6) (CYPXIA1) (P450(scc)) (Cholesterol side-chain cleavage enzyme) (Cholesterol desmolase) Length = 520 Score = 59.3 bits (142), Expect = 1e-08 Identities = 39/126 (30%), Positives = 61/126 (48%) Frame = -3 Query: 682 ILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANR 503 +L + +L IK LRLHP + L R SD + +++ IP +V + R Sbjct: 369 MLQMVPLLKASIKETLRLHPISVTLQRYPESDLVL-----QDYLIPAKTLVQVAIYAMGR 423 Query: 502 LPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLR 323 P F +PD +DP R+ + +DK F + FG G C+G A L++ H+L Sbjct: 424 DPAFFSSPDKFDPTRWLS---KDKDLIHFRNLGFGWGVRQCVGRRIAELEMTLFLIHILE 480 Query: 322 NFEFEL 305 NF+ E+ Sbjct: 481 NFKVEM 486
>C84A1_ARATH (Q42600) Cytochrome P450 84A1 (EC 1.14.-.-)| (Ferulate-5-hydroxylase) (F5H) Length = 520 Score = 59.3 bits (142), Expect = 1e-08 Identities = 36/131 (27%), Positives = 59/131 (45%) Frame = -3 Query: 697 KIDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSP 518 +++ + ++ L +K LR+HPP+ +LL ++ D S+ F IPK V + Sbjct: 358 RVEESDIEKLTYLKCTLKETLRMHPPIPLLLHETAEDTSIDG-----FFIPKKSRVMINA 412 Query: 517 AFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIW 338 R P + +PD++ P RF D F +I FG GR C G + Sbjct: 413 FAIGRDPTSWTDPDTFRPSRFLEPGVPDFKGSNFEFIPFGSGRRSCPGMQLGLYALDLAV 472 Query: 337 THLLRNFEFEL 305 H+L F ++L Sbjct: 473 AHILHCFTWKL 483
>CP9H1_DROME (Q9V6H1) Probable cytochrome P450 9h1 (EC 1.14.-.-) (CYPIXH1)| Length = 518 Score = 59.3 bits (142), Expect = 1e-08 Identities = 39/129 (30%), Positives = 64/129 (49%), Gaps = 2/129 (1%) Frame = -3 Query: 694 IDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKE-FDIPKGHIVATSP 518 + +D L +M L + ALR PP I R+ D + G++ F KG ++ Sbjct: 361 LTYDKLTKMKYLDMVVLEALRKWPPSISTDRECRQDIDLFDENGQKLFSARKGDVLQIPI 420 Query: 517 AFANRLPHIFKNPDSYDPDRFAAGRE-EDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAI 341 + P F++P+ ++P+RFA G E +V Y+ FG G C+G A +++K+I Sbjct: 421 FSLHHDPENFEDPEFFNPERFADGHALESRV-----YMPFGVGPRNCIGNRMALMELKSI 475 Query: 340 WTHLLRNFE 314 LL NF+ Sbjct: 476 VYQLLLNFK 484
>CP4E1_DROME (Q9V4T5) Probable cytochrome P450 4e1 (EC 1.14.-.-) (CYPIVE1)| Length = 531 Score = 59.3 bits (142), Expect = 1e-08 Identities = 35/113 (30%), Positives = 57/113 (50%), Gaps = 1/113 (0%) Frame = -3 Query: 649 IKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDI-PKGHIVATSPAFANRLPHIFKNPDS 473 IK A RL+P + + R + D+ + + DI PKG + +FK+P Sbjct: 365 IKEAQRLYPSVPFIGRFTEKDYVI------DGDIVPKGTTLNLGLLMLGYNDRVFKDPHK 418 Query: 472 YDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFE 314 + P+RF + + G F Y+ F G C+G+ FA L+IK + + ++RNFE Sbjct: 419 FQPERF-----DREKPGPFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFE 466
>CP4C1_BLADI (P29981) Cytochrome P450 4C1 (EC 1.14.14.1) (CYPIVC1)| Length = 511 Score = 58.9 bits (141), Expect = 1e-08 Identities = 35/122 (28%), Positives = 62/122 (50%) Frame = -3 Query: 679 LAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 500 LA+M L R IK +LRL P + + R D + ++ +P G ++ +R Sbjct: 360 LADMKYLERVIKESLRLFPSVPFIGRVLKEDTKIG-----DYLVPAGCMMNLQIYHVHRN 414 Query: 499 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 320 + NP++++PD F R + ++Y+ F G C+G+ FA L+ K + + +LRN Sbjct: 415 QDQYPNPEAFNPDNFLPERVAKR--HPYAYVPFSAGPRNCIGQKFATLEEKTVLSSILRN 472 Query: 319 FE 314 F+ Sbjct: 473 FK 474
>CP6J1_BLAGE (Q964R1) Cytochrome P450 6j1 (EC 1.14.-.-) (CYPVIJ1)| Length = 501 Score = 58.9 bits (141), Expect = 1e-08 Identities = 39/137 (28%), Positives = 66/137 (48%) Frame = -3 Query: 697 KIDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSP 518 K+ + + +M L + LR +P + L R+ D+ +T ++ +P G V Sbjct: 345 KVTYYSIKDMKYLDMVVNETLRKYPAIPFLDRRCQEDYPLT----QDLMLPAGTGVYIPV 400 Query: 517 AFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIW 338 + F +P +DP+RF+ +++ F+Y+ FG G C+G F +Q+KA Sbjct: 401 YALHHDSKYFPSPAKFDPERFSEKNKQN--IPHFAYMPFGEGPRNCIGMRFGSMQVKAAL 458 Query: 337 THLLRNFEFELVSPFPE 287 H+L NFE VSP E Sbjct: 459 IHILSNFE---VSPCKE 472
>CP4E3_DROME (Q9VL92) Cytochrome P450 4e3 (EC 1.14.-.-) (CYPIVE3)| Length = 526 Score = 58.9 bits (141), Expect = 1e-08 Identities = 37/122 (30%), Positives = 62/122 (50%) Frame = -3 Query: 679 LAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 500 +A+M L IK A R++P + + R D+ + +PKG + + Sbjct: 354 IAKMKYLDLFIKEAQRVYPSVPFIGRYCDKDYDINGSI-----VPKGTTLNLALILLGYN 408 Query: 499 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 320 IFK+P + P+RF EE+K A F Y+ F G C+G+ FA L++K + + ++R+ Sbjct: 409 DRIFKDPHHFRPERF----EEEKPA-PFEYLPFSAGPRNCIGQKFALLELKTVISKVVRS 463 Query: 319 FE 314 FE Sbjct: 464 FE 465
>C71A4_SOLME (P37117) Cytochrome P450 71A4 (EC 1.14.-.-) (CYPLXXIA4) (P-450EG2)| Length = 507 Score = 58.9 bits (141), Expect = 1e-08 Identities = 45/137 (32%), Positives = 62/137 (45%), Gaps = 6/137 (4%) Frame = -3 Query: 697 KIDHDILAEMDVLYRCIKXALRLHPPLIMLL-RQSHSDFSVTTREGKEFDIPKGHIVATS 521 +I D L M L IK +LRLHPP +L+ R+S D + + HI A + Sbjct: 347 EITEDDLKNMQYLRAVIKESLRLHPPNSLLVPRESMEDVKL---------LGYYHIPART 397 Query: 520 PAFAN-----RLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYL 356 A N R P ++NP+ + P+RF + D F + FG GR GC G FA Sbjct: 398 QALINVWAIGRDPLSWENPEEFCPERFL-NNDIDMKGLKFELLPFGSGRRGCPGSSFAIA 456 Query: 355 QIKAIWTHLLRNFEFEL 305 I+ L+ F F L Sbjct: 457 VIELALARLVHKFNFAL 473
>C4D14_DROME (O46051) Probable cytochrome P450 4d14 (EC 1.14.-.-) (CYPIVD14)| Length = 507 Score = 58.9 bits (141), Expect = 1e-08 Identities = 40/123 (32%), Positives = 63/123 (51%) Frame = -3 Query: 682 ILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANR 503 +L E+ L IK +LRL P + ++ R D T +GK IP V A R Sbjct: 361 LLGELKYLECVIKESLRLFPSVPIIGRYISQD---TVLDGKL--IPADSNVIILIYHAQR 415 Query: 502 LPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLR 323 P F +P+ + PDRF+ R+ + F+Y F G C+G+ FA L++K+ + ++R Sbjct: 416 DPDYFPDPEKFIPDRFSMERKGE--ISPFAYTPFSAGPRNCIGQKFAMLEMKSTISKMVR 473 Query: 322 NFE 314 +FE Sbjct: 474 HFE 476
>CP6D3_MUSDO (Q964Q7) Cytochrome P450 6d3 (EC 1.14.-.-) (CYPVID3) (Pyrethroid| resistance cytochrome P450) Length = 520 Score = 58.9 bits (141), Expect = 1e-08 Identities = 42/139 (30%), Positives = 61/139 (43%) Frame = -3 Query: 697 KIDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSP 518 +I ++ + +M L C+K R +P L L RQ DF V +F I K V S Sbjct: 362 RITYEAIQDMKYLDLCVKETTRKYPGLPFLNRQCTQDFKV---PNSKFTIKKDTNVIISL 418 Query: 517 AFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIW 338 +R F P +Y P+RFA +E K A +Y+ FG G C+ + + K Sbjct: 419 LGLHRDAKYFPEPLAYKPERFA---DETKDYDAAAYMPFGEGPRHCIAQRMGVMNTKVAL 475 Query: 337 THLLRNFEFELVSPFPEND 281 +L NF E P P + Sbjct: 476 AKILANFNIE---PMPHKE 491
>CP11A_PIG (P10612) Cytochrome P450 11A1, mitochondrial precursor (EC| 1.14.15.6) (CYPXIA1) (P450(scc)) (Cholesterol side-chain cleavage enzyme) (Cholesterol desmolase) Length = 520 Score = 58.9 bits (141), Expect = 1e-08 Identities = 40/126 (31%), Positives = 61/126 (48%) Frame = -3 Query: 682 ILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANR 503 +L + +L IK LRLHP + L R +D + +++ IP +V + R Sbjct: 369 MLQLVPLLKASIKETLRLHPISVTLQRYLVNDLVL-----RDYMIPAKTLVQVAVYAMGR 423 Query: 502 LPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLR 323 P F NP +DP R+ G+E D + F + FG G C+G A L++ H+L Sbjct: 424 DPAFFSNPGQFDPTRWL-GKERDLIH--FRNLGFGWGVRQCVGRRIAELEMTLFLIHILE 480 Query: 322 NFEFEL 305 NF+ EL Sbjct: 481 NFKVEL 486
>THAS_MOUSE (P36423) Thromboxane-A synthase (EC 5.3.99.5) (TXA synthase) (TXS)| (TS) Length = 533 Score = 58.9 bits (141), Expect = 1e-08 Identities = 36/127 (28%), Positives = 56/127 (44%) Frame = -3 Query: 688 HDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFA 509 H + + L I LR++PP R++ D V + IP G ++ + Sbjct: 384 HSLQEGLPYLDMVISETLRMYPPAFRFTREAAQDCEVLGQR-----IPAGTVLEIAVGAL 438 Query: 508 NRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHL 329 + P + NP+++DP+RF A E F+Y+ FG G CLG L +K + Sbjct: 439 HHDPEHWPNPETFDPERFTA--EARLQRRPFTYLPFGAGPRSCLGVRLGLLVVKLTILQV 496 Query: 328 LRNFEFE 308 L F FE Sbjct: 497 LHKFRFE 503
>C71A2_SOLME (P37118) Cytochrome P450 71A2 (EC 1.14.-.-) (CYPLXXIA2) (P-450EG4)| Length = 505 Score = 58.9 bits (141), Expect = 1e-08 Identities = 46/138 (33%), Positives = 62/138 (44%), Gaps = 7/138 (5%) Frame = -3 Query: 697 KIDHDILAEMDVLYRCIKXALRLHPPLIMLL--RQSHSDFSVTTREGKEFDIPKGHIVAT 524 +I D L M L IK +LRLHP LL R+S D ++ + HI A Sbjct: 346 EITEDDLKNMQYLRAVIKESLRLHPTQESLLVPRESMEDVNL---------LGYYHIPAR 396 Query: 523 SPAFAN-----RLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAY 359 + A N R P ++NP+ Y P+RF + D F + FG GR GC G FA Sbjct: 397 TQAIINAWAIGRDPLSWENPEEYQPERFL-NSDADVKGLNFKLLPFGAGRRGCPGSSFAI 455 Query: 358 LQIKAIWTHLLRNFEFEL 305 I+ L+ F+F L Sbjct: 456 AVIELALARLVHKFDFAL 473
>C71BO_ARATH (Q9LTL8) Cytochrome P450 71B24 (EC 1.14.-.-)| Length = 498 Score = 58.2 bits (139), Expect = 2e-08 Identities = 42/141 (29%), Positives = 71/141 (50%), Gaps = 1/141 (0%) Frame = -3 Query: 700 DKIDHDILAEMDVLYRCIKXALRLHPPLIMLL-RQSHSDFSVTTREGKEFDIPKGHIVAT 524 +KI+ D + ++ L +K LRLHP +LL R++ S + + ++IP I+ Sbjct: 341 EKIEEDDVDKLQYLKLVVKETLRLHPAAPLLLPRETMSQIKI-----QGYNIPSKTILLV 395 Query: 523 SPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKA 344 + R P +KNP+ ++P+RF + K +F + FG GR C G FA ++ Sbjct: 396 NVWSIGRDPKHWKNPEEFNPERFIDCPIDYK-GNSFEMLPFGSGRRICPGIAFAIATVEL 454 Query: 343 IWTHLLRNFEFELVSPFPEND 281 +LL +F++ L PE D Sbjct: 455 GLLNLLYHFDWRL----PEED 471
>CP4AE_RAT (P20817) Cytochrome P450 4A14 precursor (EC 1.14.15.3) (CYPIVA14)| (Lauric acid omega-hydroxylase) (P450-LA-omega 3) Length = 507 Score = 58.2 bits (139), Expect = 2e-08 Identities = 40/124 (32%), Positives = 59/124 (47%) Frame = -3 Query: 685 DILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFAN 506 D L ++ CIK ALRL+PP+ + R+ S VT +G+ IPKG + Sbjct: 361 DHLDQIPYTTMCIKEALRLYPPVPSVSRELSSP--VTFPDGRS--IPKGITTTILIYGLH 416 Query: 505 RLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLL 326 P + NP +DP RF+ D + +Y+ F GG C+G+ FA ++K L Sbjct: 417 HNPSYWPNPKVFDPSRFSP----DSPRHSHAYLPFSGGARNCIGKQFAMNELKVAVALTL 472 Query: 325 RNFE 314 FE Sbjct: 473 LRFE 476
>CP3AP_MOUSE (O09158) Cytochrome P450 3A25 (EC 1.14.14.1) (CYPIIIA25)| Length = 503 Score = 58.2 bits (139), Expect = 2e-08 Identities = 38/126 (30%), Positives = 59/126 (46%) Frame = -3 Query: 694 IDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPA 515 + +D L +M+ L + +LRL+P I L R S D + IPKG +V Sbjct: 345 VTYDALMDMEYLDMVVNESLRLYPIAIRLERVSKKDVEING-----VFIPKGTVVMIPIY 399 Query: 514 FANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWT 335 +R P + P + P+RF+ +E + Y+ FG G C+G FA + IK Sbjct: 400 PLHRNPEYWPEPQEFCPERFS--KENKGNIDPYIYMPFGNGPRNCIGMRFALISIKLAVI 457 Query: 334 HLLRNF 317 +L+NF Sbjct: 458 GVLQNF 463
>C11B1_BOVIN (P15150) Cytochrome P450 11B1, mitochondrial precursor (EC| 1.14.15.4) (CYPXIB1) (P450C11) (Steroid 11-beta-hydroxylase) Length = 503 Score = 58.2 bits (139), Expect = 2e-08 Identities = 37/124 (29%), Positives = 60/124 (48%) Frame = -3 Query: 679 LAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 500 + E+ +L +K LRL+P I L R+ SD + + + IP G +V R Sbjct: 359 ITELPLLRAALKETLRLYPVGITLEREVSSDLVL-----QNYHIPAGTLVKVLLYSLGRN 413 Query: 499 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 320 P +F P+SY P R+ + F +++FG G CLG A +++ + H+L+N Sbjct: 414 PAVFARPESYHPQRWL---DRQGSGSRFPHLAFGFGVRQCLGRRVAEVEMLLLLHHVLKN 470 Query: 319 FEFE 308 F E Sbjct: 471 FLVE 474
>THAS_RAT (P49430) Thromboxane-A synthase (EC 5.3.99.5) (TXA synthase) (TXS)| Length = 533 Score = 57.8 bits (138), Expect = 3e-08 Identities = 34/115 (29%), Positives = 54/115 (46%), Gaps = 1/115 (0%) Frame = -3 Query: 649 IKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRLPHIFKNPDSY 470 + LR++PP R++ D V + IP G ++ + + P + NP+++ Sbjct: 397 VAETLRMYPPAFRFTREAAQDCEVLGQH-----IPAGSVLEIAVGALHHDPEHWPNPETF 451 Query: 469 DPDRFAA-GREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFE 308 DP+RF A R + K F+Y+ FG G CLG L +K +L F FE Sbjct: 452 DPERFTAEARLQQK---PFTYLPFGAGPRSCLGVRLGLLVVKLTLLQVLHKFRFE 503
>THAS_HUMAN (P24557) Thromboxane-A synthase (EC 5.3.99.5) (TXA synthase) (TXS)| Length = 533 Score = 57.8 bits (138), Expect = 3e-08 Identities = 32/114 (28%), Positives = 55/114 (48%) Frame = -3 Query: 649 IKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRLPHIFKNPDSY 470 I LR++PP R++ D V + IP G ++ + + P + +P+++ Sbjct: 397 IAETLRMYPPAFRFTREAAQDCEVLGQR-----IPAGAVLEMAVGALHHDPEHWPSPETF 451 Query: 469 DPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFE 308 +P+RF A E + F+Y+ FG G CLG L++K H+L F F+ Sbjct: 452 NPERFTA--EARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQ 503
>CP4A2_RAT (P20816) Cytochrome P450 4A2 precursor (EC 1.14.15.3) (CYPIVA2)| (Lauric acid omega-hydroxylase) (P450-LA-omega 2) (P450 K-5) (P-450 K-2) Length = 504 Score = 57.4 bits (137), Expect = 4e-08 Identities = 41/124 (33%), Positives = 59/124 (47%) Frame = -3 Query: 685 DILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFAN 506 D L +M CIK ALRL+ P+ + R+ S VT +G+ IPKG V + Sbjct: 358 DHLDQMPYTTMCIKEALRLYSPVPSVSRELSSP--VTFPDGRS--IPKGIRVTILIYGLH 413 Query: 505 RLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLL 326 P + NP +DP RF+ D + +Y+ F GG C+G+ FA ++K L Sbjct: 414 HNPSYWPNPKVFDPSRFSP----DSPRHSHAYLPFSGGARNCIGKQFAMNELKVAVALTL 469 Query: 325 RNFE 314 FE Sbjct: 470 LRFE 473
>CP3A1_RAT (P04800) Cytochrome P450 3A1 (EC 1.14.14.1) (CYPIIIA1) (P450-PCN1)| Length = 504 Score = 57.4 bits (137), Expect = 4e-08 Identities = 36/127 (28%), Positives = 59/127 (46%) Frame = -3 Query: 688 HDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFA 509 +D + EM+ L + LRL+P L R D + +PKG +V Sbjct: 348 YDTVMEMEYLDMVLNETLRLYPIGNRLERVCKKDVEING-----VFMPKGSVVMIPSYAL 402 Query: 508 NRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHL 329 +R P + P+ + P+RF+ +E + Y+ FG G C+G FA + +K T + Sbjct: 403 HRDPQHWPEPEEFRPERFS--KENKGSIDPYVYLPFGNGPRNCIGMRFALMNMKLALTKV 460 Query: 328 LRNFEFE 308 L+NF F+ Sbjct: 461 LQNFSFQ 467
>CP11A_HORSE (O46515) Cytochrome P450 11A1, mitochondrial precursor (EC| 1.14.15.6) (CYPXIA1) (P450(scc)) (Cholesterol side-chain cleavage enzyme) (Cholesterol desmolase) Length = 520 Score = 57.4 bits (137), Expect = 4e-08 Identities = 37/120 (30%), Positives = 56/120 (46%) Frame = -3 Query: 664 VLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRLPHIFK 485 +L IK LRLHP + L R +D + +++ IP +V S + P F Sbjct: 375 LLKASIKETLRLHPIAVTLQRYPQNDLVI-----RDYMIPAKTLVQVSIYTMGQDPTFFS 429 Query: 484 NPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL 305 NP +DP R+ +++K F + FG G CLG A L++ H+L NF E+ Sbjct: 430 NPRRFDPTRWL---DKNKDLTHFRNLGFGWGVRQCLGRRIAELEMTLFLIHILENFRVEI 486
>CP3AC_CANFA (P24463) Cytochrome P450 3A12 (EC 1.14.14.1) (CYPIIIA12)| (P450-PBD-1) Length = 503 Score = 57.4 bits (137), Expect = 4e-08 Identities = 35/127 (27%), Positives = 60/127 (47%) Frame = -3 Query: 688 HDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFA 509 +D L +M+ L + LRL+P L R D ++ IPKG +V Sbjct: 347 YDALVQMEYLDMVLNETLRLYPIAGRLERVCKKDVEISG-----VFIPKGTVVMVPTFTL 401 Query: 508 NRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHL 329 +R ++ P+ + P+RF+ R+ ++Y+ FG G C+G FA + +K + Sbjct: 402 HRDQSLWPEPEEFRPERFS--RKNKDSINPYTYLPFGTGPRNCIGMRFAIMNMKLALVRV 459 Query: 328 LRNFEFE 308 L+NF F+ Sbjct: 460 LQNFSFK 466
>C98A3_ARATH (O22203) Cytochrome P450 98A3 (EC 1.14.-.-)| Length = 508 Score = 57.4 bits (137), Expect = 4e-08 Identities = 36/112 (32%), Positives = 56/112 (50%), Gaps = 1/112 (0%) Frame = -3 Query: 649 IKXALRLHPPL-IMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRLPHIFKNPDS 473 +K + RLHPP +ML +S++D + +DIPKG V + R P ++KNP Sbjct: 354 VKESFRLHPPTPLMLPHRSNADVKIGG-----YDIPKGSNVHVNVWAVARDPAVWKNPFE 408 Query: 472 YDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNF 317 + P+RF + D F + FG GR C G + ++ +HLL +F Sbjct: 409 FRPERFLE-EDVDMKGHDFRLLPFGAGRRVCPGAQLGINLVTSMMSHLLHHF 459
>CP317_DROME (Q9V776) Probable cytochrome P450 317a1 (EC 1.14.-.-)| (CYPCCCXVIIA1) Length = 518 Score = 57.4 bits (137), Expect = 4e-08 Identities = 34/130 (26%), Positives = 66/130 (50%) Frame = -3 Query: 694 IDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPA 515 I H+ + + + + I LR+HP +LR++ +D++V + ++ + K + Sbjct: 361 ITHEGIKSLSFMGQVINETLRMHPITPYILRRTLNDYAVP--DHPKYILVKELFLIIPTH 418 Query: 514 FANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWT 335 + P I+ +P+ + PDR++ R+ + G ++ FG G C+G FA LQ++ Sbjct: 419 AIHHDPDIYPDPEEFKPDRWSGPRDSLQEQG--TWFGFGVGARSCIGIQFAQLQLRLALA 476 Query: 334 HLLRNFEFEL 305 LL +EF L Sbjct: 477 LLLSEYEFSL 486
>CP6A1_MUSDO (P13527) Cytochrome P450 6A1 (EC 1.14.14.1) (CYPVIA1)| Length = 509 Score = 57.4 bits (137), Expect = 4e-08 Identities = 37/136 (27%), Positives = 67/136 (49%), Gaps = 2/136 (1%) Frame = -3 Query: 700 DKIDHDILAEMDVLYRCIKXALRLHPPLI--MLLRQSHSDFSVTTREGKEFDIPKGHIVA 527 D I +D L + L + + LR +P + L RQ+ +D+ V ++ +PKG +V Sbjct: 345 DNISYDALMNIPYLDQVLNETLRKYPVGVGSALTRQTLNDYVVP--HNPKYVLPKGTLVF 402 Query: 526 TSPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIK 347 + P ++ NP+ +DP+RF+ E K + ++ FG G C+G F +Q + Sbjct: 403 IPVLGIHYDPELYPNPEEFDPERFSP--EMVKQRDSVDWLGFGDGPRNCIGMRFGKMQSR 460 Query: 346 AIWTHLLRNFEFELVS 299 ++R+F F + S Sbjct: 461 LGLALVIRHFRFTVCS 476
>C76C4_ARATH (O64635) Cytochrome P450 76C4 (EC 1.14.-.-)| Length = 511 Score = 57.0 bits (136), Expect = 5e-08 Identities = 37/126 (29%), Positives = 62/126 (49%), Gaps = 1/126 (0%) Frame = -3 Query: 679 LAEMDVLYRCIKXALRLHPPLIMLL-RQSHSDFSVTTREGKEFDIPKGHIVATSPAFANR 503 ++ + L +K RLHP +L+ R++ SD V F +PK V + R Sbjct: 356 ISGLPYLQAVVKETFRLHPAAPLLVPRKAESDVEVLG-----FMVPKDTQVLVNVWAIGR 410 Query: 502 LPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLR 323 P +++NP ++P+RF G++ D + FGGGR C G P A + + LL Sbjct: 411 DPSVWENPSQFEPERFM-GKDIDVKGRDYELTPFGGGRRICPGLPLAVKTVSLMLASLLY 469 Query: 322 NFEFEL 305 +F+++L Sbjct: 470 SFDWKL 475
>CP3AS_BOVIN (P79102) Cytochrome P450 3A28 (EC 1.14.14.1) (CYPIIIA28)| Length = 507 Score = 57.0 bits (136), Expect = 5e-08 Identities = 35/127 (27%), Positives = 56/127 (44%) Frame = -3 Query: 688 HDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFA 509 +D L +M+ L + LR+ P L R D + IPKG V Sbjct: 347 YDALVQMEYLDMVVNETLRMFPIAGRLERVCKKDVEI-----HGVTIPKGTTVLVPLFVL 401 Query: 508 NRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHL 329 + P ++ P+ + P+RF+ ++ + Y+ FG G CLG FA + IK + Sbjct: 402 HNNPELWPEPEEFRPERFSKNNKDS--INPYVYLPFGTGPRNCLGMRFAIMNIKLALVRI 459 Query: 328 LRNFEFE 308 L+NF F+ Sbjct: 460 LQNFSFK 466
>CP3AB_MOUSE (Q64459) Cytochrome P450 3A11 (EC 1.14.14.1) (CYPIIIA11)| (P-450IIIAM1) (P-450UT) Length = 504 Score = 57.0 bits (136), Expect = 5e-08 Identities = 36/127 (28%), Positives = 57/127 (44%) Frame = -3 Query: 688 HDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFA 509 +D + EM+ L + LRL+P L R D + IPKG V Sbjct: 348 YDTVMEMEYLDMVLNETLRLYPIANRLERVCKKDVELNG-----VYIPKGSTVMIPSYAL 402 Query: 508 NRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHL 329 + P + P+ + P+RF+ +E + Y+ FG G CLG FA + +K T + Sbjct: 403 HHDPQHWSEPEEFQPERFS--KENKGSIDPYVYLPFGNGPRNCLGMRFALMNMKLALTKI 460 Query: 328 LRNFEFE 308 ++NF F+ Sbjct: 461 MQNFSFQ 467
>CP39A_HUMAN (Q9NYL5) Cytochrome P450 39A1 (EC 1.14.13.99)| (24-hydroxycholesterol 7-alpha-hydroxylase) (Oxysterol 7-alpha-hydroxylase) (hCYP39A1) Length = 469 Score = 57.0 bits (136), Expect = 5e-08 Identities = 39/161 (24%), Positives = 78/161 (48%), Gaps = 3/161 (1%) Frame = -3 Query: 697 KIDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSP 518 K+ D L ++ ++ C+ +RL P ++ + V E + IP G ++ SP Sbjct: 316 KVSEDDLEKLLLIKWCVLETIRLKAPGVITRKV------VKPVEILNYIIPSGDLLMLSP 369 Query: 517 AFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIW 338 + +R P F P+ + P+R+ E K + +++FG G+ C FA L+++ Sbjct: 370 FWLHRNPKYFPEPELFKPERWKKANLE-KHSFLDCFMAFGSGKFQCPARWFALLEVQMCI 428 Query: 337 THLLRNFEFELVSPFPENDWNAMVVGI---KGEVMVNYKRR 224 +L ++ L+ P P+ + +VG+ +G+ + YK+R Sbjct: 429 ILILYKYDCSLLDPLPKQSY-LHLVGVPQPEGQCRIEYKQR 468
>C80A1_BERST (P47195) Berbamunine synthase (EC 1.14.21.3) (Cytochrome P450 80)| (CYPLXXX) ((S)-N-methylcoclaurine oxidase [C-O phenol-coupling]) Length = 487 Score = 57.0 bits (136), Expect = 5e-08 Identities = 38/129 (29%), Positives = 59/129 (45%) Frame = -3 Query: 676 AEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRLP 497 +E+ L C+K +RL+PP+ +++ + T + + IPKG V + R P Sbjct: 336 SELPYLQACVKETMRLYPPISIMIPHR----CMETCQVMGYTIPKGMDVHVNAHAIGRDP 391 Query: 496 HIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNF 317 +K+P + P+RF E F +I FG GR C G P A I + L+ F Sbjct: 392 KDWKDPLKFQPERFLDSDIEYN-GKQFQFIPFGSGRRICPGRPLAVRIIPLVLASLVHAF 450 Query: 316 EFELVSPFP 290 +EL P Sbjct: 451 GWELPDGVP 459
>CP6T1_DROME (Q9VRI9) Probable cytochrome P450 6t1 (EC 1.14.-.-) (CYPVIT1)| Length = 529 Score = 57.0 bits (136), Expect = 5e-08 Identities = 38/130 (29%), Positives = 63/130 (48%), Gaps = 3/130 (2%) Frame = -3 Query: 685 DILAEMDVLYRCIKXALRLHPPLIMLLR--QSHSDFSVTT-REGKEFDIPKGHIVATSPA 515 D + + L + + LRL+PP L R S + + ++ G F + G V S Sbjct: 370 DTVTGLVYLRQVVDEVLRLYPPTAFLDRCCNSRTGYDLSPWNGGSPFKLRAGTPVYISVL 429 Query: 514 FANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWT 335 +R + NP+ +DP+RF+A E+ + +Y+ FG G GC+G L+IK Sbjct: 430 GIHRDAQYWPNPEVFDPERFSA--EQRQQHHPMTYLPFGAGPRGCIGTLLGQLEIKVGLL 487 Query: 334 HLLRNFEFEL 305 H+L +F E+ Sbjct: 488 HILNHFRVEV 497
>CP310_DROME (Q9VJ71) Probable cytochrome P450 310a1 (EC 1.14.-.-) (CYPCCCXA1)| Length = 492 Score = 56.6 bits (135), Expect = 7e-08 Identities = 47/154 (30%), Positives = 67/154 (43%), Gaps = 9/154 (5%) Frame = -3 Query: 652 CIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRLPHIFKNPDS 473 C+K LR +PPL ++ R +S+ +F I +G + +R F P Sbjct: 337 CLKETLRKYPPLPIIERVCRKSYSLPN---SKFTIDEGKTLMVPLLAMHRDEKYFSEPMK 393 Query: 472 YDPDRFA-----AGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFE 308 Y P RF G+ EDK +I FG G C+G+ FA L IK LL+NF E Sbjct: 394 YKPLRFLQTANDVGQCEDKTKSNV-FIGFGIGGSQCVGQNFAKLVIKVALIKLLQNFHLE 452 Query: 307 L----VSPFPENDWNAMVVGIKGEVMVNYKRRKL 218 L V + A + K + V KRR++ Sbjct: 453 LDANQVKTLKVSHRPAPFIHTKDGLKVKLKRREI 486
>CYPX_BACSU (O34926) Putative cytochrome P450 cypX (EC 1.14.-.-)| Length = 405 Score = 56.6 bits (135), Expect = 7e-08 Identities = 42/130 (32%), Positives = 63/130 (48%), Gaps = 3/130 (2%) Frame = -3 Query: 688 HDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFA 509 +D+LA+ ++ R I LR PP+ ++ RQ D V E I K IV A Sbjct: 257 NDVLADRSLVPRAIAETLRYKPPVQLIPRQLSQDTVVGGME-----IKKDTIVFCMIGAA 311 Query: 508 NRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHL 329 NR P F+ PD ++ R G + +GA +++FG G H C+G FA +I+ + + Sbjct: 312 NRDPEAFEQPDVFNIHREDLGIKS-AFSGAARHLAFGSGIHNCVGAAFAKNEIEIVANIV 370 Query: 328 L---RNFEFE 308 L RN E Sbjct: 371 LDKMRNIRLE 380
>C11B1_MESAU (P97720) Cytochrome P450 11B1, mitochondrial precursor (EC| 1.14.15.4) (CYPXIB1) (P450C11) (Steroid 11-beta-hydroxylase) Length = 499 Score = 56.2 bits (134), Expect = 9e-08 Identities = 34/124 (27%), Positives = 62/124 (50%) Frame = -3 Query: 679 LAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 500 ++++ +L +K LRL+P + L R SD + + + +P G I+ S R Sbjct: 358 MSDLPLLRAVLKETLRLYPVAVFLERILSSDLVL-----QNYHVPAGTILHMSLYSMGRN 412 Query: 499 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 320 P +F P+ Y P R+ G+F +++FG G CLG+ A +++ + H+L++ Sbjct: 413 PAVFPRPEHYLPQRWLERN------GSFQHLTFGFGVRQCLGKRLAQVEMLLLLHHVLKS 466 Query: 319 FEFE 308 F E Sbjct: 467 FRVE 470
>CP6T3_DROME (Q9V676) Probable cytochrome P450 6t3 (EC 1.14.-.-) (CYPVIT3)| Length = 501 Score = 56.2 bits (134), Expect = 9e-08 Identities = 38/131 (29%), Positives = 59/131 (45%), Gaps = 2/131 (1%) Frame = -3 Query: 694 IDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFS--VTTREGKEFDIPKGHIVATS 521 + +D L + L ALRL+P + R+ S S + + +F +P G S Sbjct: 340 LSYDTLMTLPYLKMVCLEALRLYPAAAFVNRECTSSASEGFSLQPHVDFIVPPGMPAYIS 399 Query: 520 PAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAI 341 +R + P +DP+RF G E + +YI FG G HGC+G LQ+K Sbjct: 400 ILGLHRDERFWPEPCVFDPERF--GPERSRHIHPMTYIPFGAGPHGCIGSRLGVLQLKLG 457 Query: 340 WTHLLRNFEFE 308 H+L+ + E Sbjct: 458 IVHILKQYWVE 468
>C6A20_DROME (Q9V773) Probable cytochrome P450 6a20 (EC 1.14.-.-) (CYPVIA20)| Length = 501 Score = 56.2 bits (134), Expect = 9e-08 Identities = 37/132 (28%), Positives = 64/132 (48%), Gaps = 2/132 (1%) Frame = -3 Query: 697 KIDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSP 518 K+D+D + EM L + I +R P + L+R + + T +++I KG V Sbjct: 345 KLDYDSMREMTYLEKVIDETMRKRPVVGHLIRVATQHYQHTN---PKYNIEKGTGVIVPT 401 Query: 517 AFANRLPHIFKNPDSYDPDRFAAGREEDKVAG--AFSYISFGGGRHGCLGEPFAYLQIKA 344 + P + P+ + P+RF +ED+V A +++ FG G C+G F +Q+ Sbjct: 402 LAIHHDPEFYPEPEKFIPERF----DEDQVQQRPACTFLPFGDGPRNCIGLRFGRMQVIV 457 Query: 343 IWTHLLRNFEFE 308 L+ NF+FE Sbjct: 458 GMALLIHNFKFE 469
>C4D20_DROME (Q9W011) Probable cytochrome P450 4d20 (EC 1.14.-.-) (CYPIVD20)| Length = 510 Score = 56.2 bits (134), Expect = 9e-08 Identities = 33/122 (27%), Positives = 62/122 (50%) Frame = -3 Query: 679 LAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 500 L ++ L IK +RL+PP+ + R + + + + IP + +A+R Sbjct: 363 LQDLKYLDCVIKETMRLYPPVPAIGRHAQKELEIGDKT-----IPANTSIYLVLYYAHRD 417 Query: 499 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 320 + F +P S+ P+RF +E+ F+Y+ F G C+G+ FA L++K + + +LR Sbjct: 418 ANYFPDPLSFRPERFLEDQEQGH--NTFAYVPFSAGPKNCIGQKFAVLEMKVLISKVLRF 475 Query: 319 FE 314 +E Sbjct: 476 YE 477
>CP6W1_DROME (Q9V9L1) Probable cytochrome P450 6w1 (EC 1.14.-.-) (CYPVIW1)| Length = 514 Score = 56.2 bits (134), Expect = 9e-08 Identities = 36/133 (27%), Positives = 59/133 (44%), Gaps = 3/133 (2%) Frame = -3 Query: 700 DKIDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFS---VTTREGKEFDIPKGHIV 530 D I ++ + EM L + + LR +P + + R+ T ++P G + Sbjct: 343 DHISYERIQEMPYLSQVVNETLRKYPIVGYIERECSQPAEGERFTLEPFHNMELPHGMSI 402 Query: 529 ATSPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQI 350 S +R P + +P+ YDP+RF + ++ A Y+ FG G C+G LQ Sbjct: 403 YMSTVAVHRDPQYWPDPEKYDPERFNSSNRDNLNMDA--YMPFGVGPRNCIGMRLGLLQS 460 Query: 349 KAIWTHLLRNFEF 311 K H+LRN F Sbjct: 461 KLGLVHILRNHRF 473
>ERG5_YEAST (P54781) Cytochrome P450 61 (EC 1.14.14.-) (C-22 sterol desaturase)| Length = 538 Score = 56.2 bits (134), Expect = 9e-08 Identities = 37/159 (23%), Positives = 76/159 (47%), Gaps = 1/159 (0%) Frame = -3 Query: 697 KIDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSP 518 +++ D++ +M IK LR PP++M+ +F V+ + PKG ++ + Sbjct: 377 ELNLDLIEKMKYTNMVIKETLRYRPPVLMVPYVVKKNFPVSPN----YTAPKGAMLIPTL 432 Query: 517 AFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIW 338 A P +++NPD + P+R+ G + + +++ FG G H CLG+ + + A+ Sbjct: 433 YPALHDPEVYENPDEFIPERWVEGSKASEAKK--NWLVFGCGPHVCLGQTYVMITFAALL 490 Query: 337 THLLRNFEF-ELVSPFPENDWNAMVVGIKGEVMVNYKRR 224 +F V+P E + K ++++ +K+R Sbjct: 491 GKFALYTDFHHTVTPLSEKIKVFATIFPKDDLLLTFKKR 529
>CP3AD_MOUSE (Q64464) Cytochrome P450 3A13 (EC 1.14.14.1) (CYPIIIA13)| Length = 503 Score = 55.8 bits (133), Expect = 1e-07 Identities = 34/124 (27%), Positives = 59/124 (47%) Frame = -3 Query: 688 HDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFA 509 +D L +M+ L + LRL+P L R +D + IPKG +V Sbjct: 347 YDTLLQMEYLDMVVNETLRLYPIAGRLERVCKTDVEING-----LFIPKGTVVMIPTFAL 401 Query: 508 NRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHL 329 ++ P + P+ + P+RF+ + +D + + Y+ FG G C+G FA + +K + Sbjct: 402 HKDPKYWPEPEEFRPERFSK-KNQDSI-NPYMYLPFGSGPRNCIGMRFALINMKVALVRV 459 Query: 328 LRNF 317 L+NF Sbjct: 460 LQNF 463
>C76C3_ARATH (O64638) Cytochrome P450 76C3 (EC 1.14.-.-)| Length = 515 Score = 55.8 bits (133), Expect = 1e-07 Identities = 37/125 (29%), Positives = 58/125 (46%) Frame = -3 Query: 679 LAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 500 + + L +K LRLHP ++ R+S SD + F +PK V + R Sbjct: 358 IPSLPYLQAIVKETLRLHPAAPLIPRKSESDVQIMG-----FLVPKNTQVVVNVWAIGRD 412 Query: 499 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 320 +++NP ++P+RF RE D F I FG GR C G A + + LL + Sbjct: 413 ASVWENPMKFEPERFLL-RETDVKGRDFELIPFGSGRRMCPGISMALKTMHMVLASLLYS 471 Query: 319 FEFEL 305 F+++L Sbjct: 472 FDWKL 476
>CP9C1_DROME (Q9W130) Cytochrome P450 9c1 (EC 1.14.-.-) (CYPIXC1)| Length = 522 Score = 55.8 bits (133), Expect = 1e-07 Identities = 33/130 (25%), Positives = 62/130 (47%), Gaps = 1/130 (0%) Frame = -3 Query: 694 IDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEF-DIPKGHIVATSP 518 +D+D L M L + +LR PP ++ R SDF + EG+ ++ + +V + Sbjct: 361 LDYDTLMGMKYLNCVVSESLRKWPPAFIVDRMCGSDFQLKDEEGEVVVNLREDDLVHINV 420 Query: 517 AFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIW 338 + P F P+ + P+RF E F+Y+ FG G+ C+G A +++K++ Sbjct: 421 GALHHDPDNFPEPEQFRPERF--DEEHKHEIRQFTYLPFGVGQRSCIGNRLALMEVKSLI 478 Query: 337 THLLRNFEFE 308 L+ + + Sbjct: 479 FQLVLRYHLK 488
>CP4V2_PONPY (Q5RCN6) Cytochrome P450 4V2 (EC 1.14.-.-)| Length = 525 Score = 55.5 bits (132), Expect = 2e-07 Identities = 35/124 (28%), Positives = 57/124 (45%) Frame = -3 Query: 679 LAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 500 L ++ L IK LRL P + + R D V + + KG P +R Sbjct: 375 LKKLRYLECVIKETLRLFPSVPLFARSVSEDCEVAG-----YRVLKGTEAVIIPYALHRD 429 Query: 499 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 320 P F NP+ + P+RF + + ++Y+ F G C+G+ FA ++ K I + +LR+ Sbjct: 430 PRYFPNPEEFQPERFFPENAQGR--HPYAYVPFSAGPRNCIGQKFAVMEEKTILSCILRH 487 Query: 319 FEFE 308 F E Sbjct: 488 FWIE 491
>CP4V2_HUMAN (Q6ZWL3) Cytochrome P450 4V2 (EC 1.14.-.-)| Length = 525 Score = 55.5 bits (132), Expect = 2e-07 Identities = 35/124 (28%), Positives = 57/124 (45%) Frame = -3 Query: 679 LAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 500 L ++ L IK LRL P + + R D V + + KG P +R Sbjct: 375 LKKLRYLECVIKETLRLFPSVPLFARSVSEDCEVAG-----YRVLKGTEAVIIPYALHRD 429 Query: 499 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 320 P F NP+ + P+RF + + ++Y+ F G C+G+ FA ++ K I + +LR+ Sbjct: 430 PRYFPNPEEFQPERFFPENAQGR--HPYAYVPFSAGPRNCIGQKFAVMEEKTILSCILRH 487 Query: 319 FEFE 308 F E Sbjct: 488 FWIE 491
>CP3A5_HUMAN (P20815) Cytochrome P450 3A5 (EC 1.14.14.1) (CYPIIIA5) (P450-PCN3)| (HLp2) Length = 502 Score = 55.5 bits (132), Expect = 2e-07 Identities = 35/127 (27%), Positives = 59/127 (46%) Frame = -3 Query: 688 HDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFA 509 +D + +M+ L + LRL P I L R D + IPKG +V Sbjct: 347 YDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEING-----VFIPKGSMVVIPTYAL 401 Query: 508 NRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHL 329 + P + P+ + P+RF+ +++D + + Y FG G C+G FA + +K + Sbjct: 402 HHDPKYWTEPEEFRPERFS--KKKDSI-DPYIYTPFGTGPRNCIGMRFALMNMKLALIRV 458 Query: 328 LRNFEFE 308 L+NF F+ Sbjct: 459 LQNFSFK 465
>CP11A_RAT (P14137) Cytochrome P450 11A1, mitochondrial precursor (EC| 1.14.15.6) (CYPXIA1) (P450(scc)) (Cholesterol side-chain cleavage enzyme) (Cholesterol desmolase) Length = 526 Score = 55.5 bits (132), Expect = 2e-07 Identities = 37/122 (30%), Positives = 56/122 (45%) Frame = -3 Query: 664 VLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRLPHIFK 485 +L IK LRLHP + L R +D + + + IP +V + R F Sbjct: 373 LLKASIKETLRLHPISVTLQRYIVNDLVL-----RNYKIPAKTLVQVASYAMGRESSFFP 427 Query: 484 NPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL 305 NP+ +DP R+ E+ + F Y+ FG G CLG A L++ ++L NF E+ Sbjct: 428 NPNKFDPTRWL---EKSQNTTHFRYLGFGWGVRQCLGRRIAELEMTIFLINVLENFRIEV 484 Query: 304 VS 299 S Sbjct: 485 QS 486
>CP6D1_MUSDO (Q27698) Cytochrome P450 6d1 (EC 1.14.-.-) (CYPVID1) (Pyrethroid| resistance cytochrome P450) (Cytochrome P450 Ipr) Length = 516 Score = 55.5 bits (132), Expect = 2e-07 Identities = 37/139 (26%), Positives = 60/139 (43%) Frame = -3 Query: 697 KIDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSP 518 ++ ++ + +M L C+ R +P L L R+ DF V + IPK + S Sbjct: 362 RLTYEAIQDMKYLDLCVMETTRKYPGLPFLNRKCTQDFQVPDTK---LTIPKETGIIISL 418 Query: 517 AFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIW 338 +R P F P+ Y P+RFA +E K +Y+ FG G C+ + + K Sbjct: 419 LGIHRDPQYFPQPEDYRPERFA---DESKDYDPAAYMPFGEGPRHCIAQRMGVMNSKVAL 475 Query: 337 THLLRNFEFELVSPFPEND 281 +L NF + P P + Sbjct: 476 AKILANFN---IQPMPRQE 491
>C71C3_MAIZE (P93703) Cytochrome P450 71C3 (EC 1.14.-.-) (Benzoxazineless 5)| Length = 535 Score = 55.5 bits (132), Expect = 2e-07 Identities = 39/144 (27%), Positives = 68/144 (47%), Gaps = 3/144 (2%) Frame = -3 Query: 700 DKIDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATS 521 D I D L+ + L +K ALRLHPP +LL +S + + IP V + Sbjct: 370 DMIREDDLSSLPYLKASMKEALRLHPPGPLLLPH----YSTADCQIDGYHIPANPRVLVN 425 Query: 520 PAFANRLPHIFKNPDSYDPDRFAAGR--EEDKVAGA-FSYISFGGGRHGCLGEPFAYLQI 350 R P +++ P+ + P+RF + + +G F Y+ FG GR C G F + Sbjct: 426 GWAIGRDPAVWEKPEEFMPERFMRDGWDKSNSYSGQDFRYLPFGSGRRICPGANFGLATM 485 Query: 349 KAIWTHLLRNFEFELVSPFPENDW 278 + + +L+ +F++E+ + + W Sbjct: 486 EIMLANLMYHFDWEVPNEKEDGCW 509
>CP3A4_HUMAN (P08684) Cytochrome P450 3A4 (EC 1.14.13.67) (Quinine| 3-monooxygenase) (CYPIIIA4) (Nifedipine oxidase) (Taurochenodeoxycholate 6-alpha-hydroxylase) (EC 1.14.13.97) (NF-25) (P450-PCN1) Length = 502 Score = 55.1 bits (131), Expect = 2e-07 Identities = 34/127 (26%), Positives = 58/127 (45%) Frame = -3 Query: 688 HDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFA 509 +D + +M+ L + LRL P + L R D + IPKG +V Sbjct: 346 YDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEING-----MFIPKGWVVMIPSYAL 400 Query: 508 NRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHL 329 +R P + P+ + P+RF+ +++ + Y FG G C+G FA + +K + Sbjct: 401 HRDPKYWTEPEKFLPERFSKKNKDN--IDPYIYTPFGSGPRNCIGMRFALMNMKLALIRV 458 Query: 328 LRNFEFE 308 L+NF F+ Sbjct: 459 LQNFSFK 465
>C71A8_MENPI (Q42716) Cytochrome P450 71A8 (EC 1.14.-.-)| Length = 502 Score = 55.1 bits (131), Expect = 2e-07 Identities = 37/131 (28%), Positives = 62/131 (47%), Gaps = 1/131 (0%) Frame = -3 Query: 694 IDHDILAEMDVLYRCIKXALRLHPPLIMLL-RQSHSDFSVTTREGKEFDIPKGHIVATSP 518 I D + +M L +K +R H P+ +L+ R + +D V +D+P G +V + Sbjct: 348 ITDDDIEKMHYLKAVMKETMRFHTPIPLLVPRVARNDVEVMG-----YDVPVGTMVMINA 402 Query: 517 AFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIW 338 R P + P+ + P+RF + K F I FG GR GC G F ++ Sbjct: 403 WAIGRDPTSWDEPEKFRPERFLNSSVDFKGLD-FELIPFGAGRRGCPGTTFPMATLEFTL 461 Query: 337 THLLRNFEFEL 305 +L++ F++EL Sbjct: 462 ANLMQKFDWEL 472
>C78A3_SOYBN (O48927) Cytochrome P450 78A3 (EC 1.14.-.-)| Length = 523 Score = 55.1 bits (131), Expect = 2e-07 Identities = 42/133 (31%), Positives = 64/133 (48%), Gaps = 5/133 (3%) Frame = -3 Query: 694 IDHDILAEMDVLYRCIKXALRLHPP--LIMLLRQSHSDFSVTTREGKEFDIPKGHIVATS 521 + D +A M L +K LRLHPP L+ R S +D TT +G + +P G + Sbjct: 363 VAEDDVAVMTYLPAVVKEVLRLHPPGPLLSWARLSIND---TTIDG--YHVPAGTTAMVN 417 Query: 520 PAFANRLPHIFKNPDSYDPDRF--AAGREEDKVAGAFSYIS-FGGGRHGCLGEPFAYLQI 350 R PH++K+P + P+RF A G E + G+ ++ FG GR C G+ + + Sbjct: 418 TWAICRDPHVWKDPLEFMPERFVTAGGDAEFSILGSDPRLAPFGSGRRACPGKTLGWATV 477 Query: 349 KAIWTHLLRNFEF 311 LL FE+ Sbjct: 478 NFWVASLLHEFEW 490
>CP3A3_HUMAN (P05184) Cytochrome P450 3A3 (EC 1.14.14.1) (CYPIIIA3) (HLp)| Length = 503 Score = 55.1 bits (131), Expect = 2e-07 Identities = 34/127 (26%), Positives = 58/127 (45%) Frame = -3 Query: 688 HDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFA 509 +D + +M+ L + LRL P + L R D + IPKG +V Sbjct: 347 YDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEING-----MFIPKGWVVMIPSYAL 401 Query: 508 NRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHL 329 +R P + P+ + P+RF+ +++ + Y FG G C+G FA + +K + Sbjct: 402 HRDPKYWTEPEKFLPERFSKKNKDN--IDPYIYTPFGSGPRNCIGMRFALMNMKLALIRV 459 Query: 328 LRNFEFE 308 L+NF F+ Sbjct: 460 LQNFSFK 466
>C6A19_DROME (P82711) Probable cytochrome P450 6a19 (EC 1.14.-.-) (CYPVIA19)| Length = 503 Score = 55.1 bits (131), Expect = 2e-07 Identities = 39/157 (24%), Positives = 74/157 (47%), Gaps = 3/157 (1%) Frame = -3 Query: 697 KIDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSP 518 K+++D + ++ + + I +LR HP + L R + + ++ I G V S Sbjct: 345 KLEYDSMQDLFYMEKVINESLRKHPVVAHLARIATKPYQ---HSNPKYFIEAGTGVLVST 401 Query: 517 AFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIW 338 + P + P+ + P+RF E+ K +++ FG G C+G F +Q+ Sbjct: 402 LGIHHDPEFYPEPEKFIPERF--DEEQVKKRPTCAFLPFGAGPRNCIGLRFGRMQVIIGL 459 Query: 337 THLLRNFEFEL--VSPFP-ENDWNAMVVGIKGEVMVN 236 L+ NF FEL +P P + N +++G +G + +N Sbjct: 460 ALLIHNFRFELHPKTPVPMKYTINNLLLGSEGGIHLN 496
>F3PH_ARATH (Q9SD85) Flavonoid 3'-monooxygenase (EC 1.14.13.21) (Flavonoid| 3'-hydroxylase) (AtF3'H) (Cytochrome P450 75B1) (TRANSPARENT TESTA 7 protein) Length = 513 Score = 54.7 bits (130), Expect = 3e-07 Identities = 39/133 (29%), Positives = 62/133 (46%), Gaps = 3/133 (2%) Frame = -3 Query: 694 IDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPA 515 ++ +A++ L IK RLHPP + L S+ + E + IPKG + T+ Sbjct: 342 VNESDIAQLPYLQAVIKENFRLHPPTPLSLPHIASE----SCEINGYHIPKGSTLLTNIW 397 Query: 514 FANRLPHIFKNPDSYDPDRFAAGREE---DKVAGAFSYISFGGGRHGCLGEPFAYLQIKA 344 R P + +P ++ P+RF G E+ D F I FG GR C G I+ Sbjct: 398 AIARDPDQWSDPLAFKPERFLPGGEKSGVDVKGSDFELIPFGAGRRICAGLSLGLRTIQF 457 Query: 343 IWTHLLRNFEFEL 305 + L++ F++EL Sbjct: 458 LTATLVQGFDWEL 470
>C11B1_PIG (Q29552) Cytochrome P450 11B1, mitochondrial precursor (EC| 1.14.15.4) (CYPXIB1) (P450C11) (Steroid 11-beta-hydroxylase) Length = 503 Score = 54.7 bits (130), Expect = 3e-07 Identities = 37/125 (29%), Positives = 62/125 (49%), Gaps = 1/125 (0%) Frame = -3 Query: 679 LAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 500 + E+ +L +K LRL+P I L R SD + + + IP G +V R Sbjct: 359 ITELPLLRAALKETLRLYPVGIFLDRCVTSDLVL-----QNYHIPAGTLVKVLLYSLGRN 413 Query: 499 PHIFKNPDSYDPDRFAAGREEDKVAGA-FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLR 323 P +F P+ Y P R+ +++ +G F +++FG G CLG A +++ + H+L+ Sbjct: 414 PAVFARPERYHPQRWL----DNQGSGTRFPHLAFGFGMRQCLGRRLAQVEMLLLLHHVLK 469 Query: 322 NFEFE 308 NF E Sbjct: 470 NFLVE 474
>CP9B2_DROME (Q9V4I1) Cytochrome P450 9b2 (EC 1.14.-.-) (CYPIXB2)| Length = 505 Score = 54.7 bits (130), Expect = 3e-07 Identities = 35/130 (26%), Positives = 63/130 (48%), Gaps = 1/130 (0%) Frame = -3 Query: 694 IDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREG-KEFDIPKGHIVATSP 518 + +D + +M + I +LR R D+++T +G K FD G + Sbjct: 346 LTYDAVQKMTYMDMVISESLRKWTLAAATDRLCSKDYTLTDDDGTKLFDFKVGDRINIPI 405 Query: 517 AFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIW 338 + + F P +DPDRF+ R+ D V ++Y+ FG G C+G +A +Q+K + Sbjct: 406 SGLHLDDRYFPEPRKFDPDRFSEERKGDMVP--YTYLPFGVGPRNCIGNRYALMQVKGML 463 Query: 337 THLLRNFEFE 308 +LL +++ E Sbjct: 464 FNLLLHYKIE 473
>CP26A_BRARE (P79739) Cytochrome P450 26A1 (EC 1.14.-.-) (Retinoic| acid-metabolizing cytochrome) (P450RAI) (Retinoic acid 4-hydroxylase) Length = 492 Score = 54.3 bits (129), Expect = 4e-07 Identities = 35/110 (31%), Positives = 55/110 (50%) Frame = -3 Query: 649 IKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRLPHIFKNPDSY 470 IK LR++PP+ R ++ T E + IPKG V S + + +F N + + Sbjct: 356 IKETLRINPPVPGGFR-----VALKTFELNGYQIPKGWNVIYSICDTHDVADVFPNKEEF 410 Query: 469 DPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 320 P+RF + ED F+YI FGGG C+G+ FA + +K L ++ Sbjct: 411 QPERFMSKGLED--GSRFNYIPFGGGSRMCVGKEFAKVLLKIFLVELTQH 458
>C76B1_HELTU (O23976) Cytochrome P450 76B1 (EC 1.14.-.-) (7-ethoxycoumarin| O-deethylase) (ECOD) (Phenylurea dealkylase) Length = 490 Score = 54.3 bits (129), Expect = 4e-07 Identities = 39/135 (28%), Positives = 61/135 (45%) Frame = -3 Query: 694 IDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPA 515 + D + + L +K LRLHPP +LL + VT E + IP G +V + Sbjct: 333 VKEDDVLRLPYLSCIVKEVLRLHPPSPLLLPRK----VVTQVELSGYTIPAGTLVFVNAW 388 Query: 514 FANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWT 335 R P ++ + + P RF R + + F I FG GR C G P A + + Sbjct: 389 AIGRDPTVWDDSLEFKPQRFLESRLDVR-GHDFDLIPFGAGRRICPGIPLATRMVPIMLG 447 Query: 334 HLLRNFEFELVSPFP 290 LL NF++++ + P Sbjct: 448 SLLNNFDWKIDTKVP 462
>CP343_HUMAN (Q9HB55) Cytochrome P450 3A43 (EC 1.14.14.1)| Length = 503 Score = 54.3 bits (129), Expect = 4e-07 Identities = 36/129 (27%), Positives = 57/129 (44%) Frame = -3 Query: 694 IDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPA 515 + +D L +M+ L + LRL P + + R D + IPKG V Sbjct: 345 VTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEING-----VFIPKGLAVMVPIY 399 Query: 514 FANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWT 335 + P + P+ + P+RF+ + +D + + YI FG G C+G FA IK Sbjct: 400 ALHHDPKYWTEPEKFCPERFSK-KNKDSI-DLYRYIPFGAGPRNCIGMRFALTNIKLAVI 457 Query: 334 HLLRNFEFE 308 L+NF F+ Sbjct: 458 RALQNFSFK 466
>C99A1_SORBI (O48957) Cytochrome P450 CYP99A1 (EC 1.14.-.-) (Fragment)| Length = 519 Score = 54.3 bits (129), Expect = 4e-07 Identities = 38/121 (31%), Positives = 56/121 (46%), Gaps = 6/121 (4%) Frame = -3 Query: 649 IKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRLPHIFKNPDSY 470 +K LRLHP L +LL +S + T + F++ KG V + R P + +P+ + Sbjct: 362 VKEGLRLHPVLPLLLPRSCQE----TCDVGGFEVTKGTKVIVNAWALARSPERWHDPEEF 417 Query: 469 DPDRFA------AGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFE 308 P+RFA A D F YI FG GR C G F ++ + LL F++ Sbjct: 418 RPERFADDDGSSAAVAVDYRGSQFEYIPFGSGRRMCPGNTFGLAALELMVARLLYYFDWS 477 Query: 307 L 305 L Sbjct: 478 L 478
>CP391_DROME (Q9VQD2) Probable cytochrome P450 309a1 (EC 1.14.-.-) (CYPCCCIXA1)| Length = 529 Score = 54.3 bits (129), Expect = 4e-07 Identities = 36/157 (22%), Positives = 64/157 (40%) Frame = -3 Query: 697 KIDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSP 518 +I +D + + L +C +LRL P+ +R + + K D+ G V Sbjct: 371 QISYDQINNLPYLDQCFNESLRLTTPIGFFMRICTKPTQINLGDDKTLDLEPGVTVMVPA 430 Query: 517 AFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIW 338 + I+ + PDRF G + ++ FG G CLG L +K Sbjct: 431 YQYHHDNDIYPEASEFRPDRFENGAAS-VLTKRGCFLPFGDGPRICLGMRVGQLSVKTAI 489 Query: 337 THLLRNFEFELVSPFPENDWNAMVVGIKGEVMVNYKR 227 H+L N++ E + P + M + + G+V + Y + Sbjct: 490 VHILSNYQVEQMKKVPLGADSGMGIFLNGDVELKYTK 526
>CP6B3_PAPPO (Q27756) Cytochrome P450 6B3 (EC 1.14.14.1) (CYPVIB4)| (CYP6B3V1/CYP6B3V2) Length = 498 Score = 53.9 bits (128), Expect = 5e-07 Identities = 47/165 (28%), Positives = 66/165 (40%), Gaps = 8/165 (4%) Frame = -3 Query: 694 IDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPA 515 I ++ L EM L R LR +P R + +D+ G + I KG + S Sbjct: 344 ITYECLGEMTFLGRVFDETLRKYPVGDFTQRNAKTDYVFP---GTDITIKKGQTIIVSTW 400 Query: 514 FANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWT 335 P + NP+ +DP+RF E K +Y+ F G CLG FA QI+ Sbjct: 401 GIQNDPKYYPNPEKFDPERF--NPENIKNRHPCAYLPFSAGPRNCLGLRFAKWQIEVCVV 458 Query: 334 HLLRNFEFELVSPFPEN--------DWNAMVVGIKGEVMVNYKRR 224 +L + E P N D + V KG + VN RR Sbjct: 459 KVLSKYRVE-----PSNKSSGEFKFDPMRLFVLPKGGIFVNIVRR 498
>C340_ORYLA (Q98T91) Cytochrome P450 3A40 (EC 1.14.14.1)| Length = 502 Score = 53.9 bits (128), Expect = 5e-07 Identities = 34/125 (27%), Positives = 60/125 (48%) Frame = -3 Query: 679 LAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 500 L EM+ L + +LRL+P L R + + T E IPK +V +R Sbjct: 351 LMEMEYLDCVVNESLRLYPIAARLERVAKA-----TVEVNGLVIPKDMVVMVPTWPLHRD 405 Query: 499 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 320 P ++ P+ + P+RF+ +E ++Y+ FG G C+G FA + +K +L+ Sbjct: 406 PELWPEPEKFKPERFS--KENKDTFDPYTYMPFGAGPRNCIGMRFALVMMKLAVVEILQT 463 Query: 319 FEFEL 305 ++F + Sbjct: 464 YDFSV 468
>T13H_TAXCU (Q8W4T9) Taxane 13-alpha-hydroxylase (EC 1.14.13.77) (Cytochrome| P450 725A2) Length = 485 Score = 53.9 bits (128), Expect = 5e-07 Identities = 33/121 (27%), Positives = 55/121 (45%) Frame = -3 Query: 679 LAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 500 L EM ++ ++ LR++PP+ R++ +D + IPKG + + Sbjct: 340 LKEMKYSWQVVQETLRMYPPIFGTFRKAITDIHYNG-----YTIPKGWKLLWTTYSTQTK 394 Query: 499 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 320 FK+ D + P RF EE K ++Y+ FGGG C G FA ++ H ++ Sbjct: 395 EEYFKDADQFKPSRF---EEEGKHVTPYTYLPFGGGMRVCPGWEFAKMETLLFLHHFVKA 451 Query: 319 F 317 F Sbjct: 452 F 452
>CP11A_HUMAN (P05108) Cytochrome P450 11A1, mitochondrial precursor (EC| 1.14.15.6) (CYPXIA1) (P450(scc)) (Cholesterol side-chain cleavage enzyme) (Cholesterol desmolase) Length = 521 Score = 53.9 bits (128), Expect = 5e-07 Identities = 37/126 (29%), Positives = 61/126 (48%) Frame = -3 Query: 682 ILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANR 503 +L + +L IK LRLHP + L R +D + +++ IP +V + R Sbjct: 370 MLQLVPLLKASIKETLRLHPISVTLQRYLVNDLVL-----RDYMIPAKTLVQVAIYALGR 424 Query: 502 LPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLR 323 P F +P+++DP R+ + +DK F + FG G CLG A L++ ++L Sbjct: 425 EPTFFFDPENFDPTRWLS---KDKNITYFRNLGFGWGVRQCLGRRIAELEMTIFLINMLE 481 Query: 322 NFEFEL 305 NF E+ Sbjct: 482 NFRVEI 487
>CP4E5_DROMT (O44221) Cytochrome P450 4e5, mitochondrial precursor (EC 1.14.-.-)| (CYPIVE5) Length = 522 Score = 53.9 bits (128), Expect = 5e-07 Identities = 33/122 (27%), Positives = 58/122 (47%) Frame = -3 Query: 679 LAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 500 ++ M L IK A R++P + + R + D+++ +PKG + Sbjct: 354 ISAMKYLDLFIKEAQRVYPSVPFIGRYTDKDYNIHGTI-----MPKGTTLNLGIIVLGYD 408 Query: 499 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 320 +F+ P + P+RF E + G F Y+ F G C+G+ FA L++K + + L+R Sbjct: 409 DRVFEEPHRFYPERF-----EKQKPGPFEYVPFSAGPRNCIGQKFALLELKTVISKLVRT 463 Query: 319 FE 314 FE Sbjct: 464 FE 465
>CP3AJ_CAPAE (P79152) Cytochrome P450 3A19 (EC 1.14.14.1) (CYPIIIA19) (Fragment)| Length = 218 Score = 53.9 bits (128), Expect = 5e-07 Identities = 34/126 (26%), Positives = 54/126 (42%) Frame = -3 Query: 688 HDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFA 509 +D L +M+ L + LR+ P L R D + IPKG V Sbjct: 58 YDALVQMEYLDMVVNETLRMFPIAGRLERLCKKDVEI-----HGVSIPKGTTVMVPLFVL 112 Query: 508 NRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHL 329 + P + P+ + P+RF+ ++ + Y+ FG G C+G FA + IK + Sbjct: 113 HNNPEFWPEPEEFRPERFSKKNKDG--INPYVYLPFGTGPRNCVGMRFALMNIKLALVRI 170 Query: 328 LRNFEF 311 L+NF F Sbjct: 171 LQNFSF 176
>CP4X1_HUMAN (Q8N118) Cytochrome P450 4X1 (EC 1.14.14.1) (CYPIVX1)| Length = 509 Score = 53.9 bits (128), Expect = 5e-07 Identities = 40/135 (29%), Positives = 60/135 (44%) Frame = -3 Query: 694 IDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPA 515 I D L EM CIK RL P + + R D S +P G V S Sbjct: 356 ITWDQLGEMSYTTMCIKETCRLIPAVPSISR----DLSKPLTFPDGCTLPAGITVVLSIW 411 Query: 514 FANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWT 335 + P ++KNP +DP RF+ +E ++Y+ F G C+G+ FA +++K Sbjct: 412 GLHHNPAVWKNPKVFDPLRFS--QENSDQRHPYAYLPFSAGSRNCIGQEFAMIELKVTIA 469 Query: 334 HLLRNFEFELVSPFP 290 +L +F V+P P Sbjct: 470 LILLHFR---VTPDP 481
>CP138_MYCTU (P63717) Putative cytochrome P450 138 (EC 1.14.-.-)| Length = 441 Score = 53.5 bits (127), Expect = 6e-07 Identities = 26/84 (30%), Positives = 45/84 (53%) Frame = -3 Query: 559 EFDIPKGHIVATSPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGC 380 E+ IP+G+ + + A + P +F PD +DP R+ + F++I FGGG C Sbjct: 334 EWVIPRGYSIIINIAQIHGDPDVFPQPDRFDPQRYIGSKPSP-----FAWIPFGGGTRRC 388 Query: 379 LGEPFAYLQIKAIWTHLLRNFEFE 308 +G FA +++ + +LR+F E Sbjct: 389 VGAAFANMEMDVVLRTVLRHFTLE 412
>CP138_MYCBO (P63718) Putative cytochrome P450 138 (EC 1.14.-.-)| Length = 441 Score = 53.5 bits (127), Expect = 6e-07 Identities = 26/84 (30%), Positives = 45/84 (53%) Frame = -3 Query: 559 EFDIPKGHIVATSPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGC 380 E+ IP+G+ + + A + P +F PD +DP R+ + F++I FGGG C Sbjct: 334 EWVIPRGYSIIINIAQIHGDPDVFPQPDRFDPQRYIGSKPSP-----FAWIPFGGGTRRC 388 Query: 379 LGEPFAYLQIKAIWTHLLRNFEFE 308 +G FA +++ + +LR+F E Sbjct: 389 VGAAFANMEMDVVLRTVLRHFTLE 412
>CP11A_MACFA (Q2XV99) Cytochrome P450 11A1, mitochondrial precursor (EC| 1.14.15.6) (CYPXIA1) (P450(scc)) (Cholesterol side-chain cleavage enzyme) (Cholesterol desmolase) Length = 521 Score = 53.5 bits (127), Expect = 6e-07 Identities = 38/126 (30%), Positives = 60/126 (47%) Frame = -3 Query: 682 ILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANR 503 IL + +L IK LRLHP + L R +D + + + IP +V + R Sbjct: 370 ILQLVPLLKASIKETLRLHPISVTLQRYLVNDLVL-----RGYMIPAKTLVQVAIYALGR 424 Query: 502 LPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLR 323 P F +P+++DP R+ + +DK F + FG G CLG A L++ ++L Sbjct: 425 EPTFFFDPENFDPTRWLS---KDKNITYFRNLGFGWGVRQCLGRRIAELEMTIFLINMLE 481 Query: 322 NFEFEL 305 NF E+ Sbjct: 482 NFRVEI 487
>CP3AG_MOUSE (Q64481) Cytochrome P450 3A16 (EC 1.14.14.1) (CYPIIIA16)| Length = 504 Score = 53.5 bits (127), Expect = 6e-07 Identities = 34/127 (26%), Positives = 55/127 (43%) Frame = -3 Query: 688 HDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFA 509 +D + M+ L + LRL+P L R D + IPKG V Sbjct: 348 YDTVMAMEYLDMVLNETLRLYPITNRLQRVCKKDVEING-----IYIPKGSTVIIPSYVL 402 Query: 508 NRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHL 329 + P + P+ + P+RF+ +E + Y+ FG G C+G FA + +K + Sbjct: 403 HHDPQHWPEPEEFQPERFS--KENKGSIDPYVYLPFGNGPRNCIGMRFALMNMKLALIKV 460 Query: 328 LRNFEFE 308 L+NF F+ Sbjct: 461 LQNFSFQ 467
>CP9B1_DROME (Q9V4I0) Cytochrome P450 9b1 (EC 1.14.-.-) (CYPIXB1)| Length = 505 Score = 53.5 bits (127), Expect = 6e-07 Identities = 35/142 (24%), Positives = 64/142 (45%), Gaps = 1/142 (0%) Frame = -3 Query: 694 IDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREG-KEFDIPKGHIVATSP 518 + +D EM + I +LR R D+++T EG K F+ G + Sbjct: 346 LTYDAAQEMTYMDMVISESLRKWTLSAAADRLCAKDYTLTDDEGTKLFEFKAGDNINIPI 405 Query: 517 AFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIW 338 + F P +DP+RF+ R++D + ++Y+ FG G C+G +A +Q K + Sbjct: 406 CGLHWDERFFPQPQRFDPERFSERRKKDLIP--YTYLPFGVGPRSCIGNRYAVMQAKGML 463 Query: 337 THLLRNFEFELVSPFPENDWNA 272 +L+ N++ E + W + Sbjct: 464 YNLMLNYKIEASPRTTRDMWES 485
>CP3AA_MESAU (Q64148) Cytochrome P450 3A10 (EC 1.14.13.94) (CYPIIIA10)| (Lithocholate 6-beta-hydroxylase) (6 beta-hydroxylase) Length = 503 Score = 53.5 bits (127), Expect = 6e-07 Identities = 37/129 (28%), Positives = 57/129 (44%) Frame = -3 Query: 694 IDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPA 515 + +D+L M+ L I LRL+P L R S + IPKG V Sbjct: 345 VTYDVLMGMEYLDMVINEGLRLYPIANRLERISKKAVEING-----LFIPKGITVMVPTY 399 Query: 514 FANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWT 335 +R P + P+ + P+RF+ +E + Y+ FG G C+G FA L +K Sbjct: 400 PLHRDPEYWPEPEEFRPERFS--KENKGSIDPYVYMPFGNGPRNCIGMRFALLSMKLAVV 457 Query: 334 HLLRNFEFE 308 +L+NF + Sbjct: 458 SVLQNFTLQ 466
>CP3A7_HUMAN (P24462) Cytochrome P450 3A7 (EC 1.14.14.1) (CYPIIIA7) (P450-HFLA)| Length = 503 Score = 53.5 bits (127), Expect = 6e-07 Identities = 32/127 (25%), Positives = 58/127 (45%) Frame = -3 Query: 688 HDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFA 509 +D + +++ L + LRL P + L R D + IPKG +V Sbjct: 347 YDTVLQLEYLDMVVNETLRLFPVAMRLERVCKKDVEING-----MFIPKGVVVMIPSYVL 401 Query: 508 NRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHL 329 + P ++ P+ + P+RF+ +++ + Y FG G C+G FA + +K + Sbjct: 402 HHDPKYWREPEKFLPERFSKKNKDN--IDPYIYTPFGSGPRNCIGMRFALVNMKLALVRV 459 Query: 328 LRNFEFE 308 L+NF F+ Sbjct: 460 LQNFSFK 466
>C71B6_ARATH (O65787) Cytochrome P450 71B6 (EC 1.14.-.-)| Length = 503 Score = 53.5 bits (127), Expect = 6e-07 Identities = 39/142 (27%), Positives = 65/142 (45%), Gaps = 1/142 (0%) Frame = -3 Query: 694 IDHDILAEMDVLYRCIKXALRLHPPL-IMLLRQSHSDFSVTTREGKEFDIPKGHIVATSP 518 + +D L + + IK RLH P I++ R++ ++F + K +DI G + + Sbjct: 347 VTYDDLEALVYMKMVIKETWRLHAPSPILIPREAMTNFKI-----KGYDIYPGTRIHVNA 401 Query: 517 AFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIW 338 R P ++K+PD + P+RF E K +F + FG GR GC P Y+ + + Sbjct: 402 WAIGRNPDVWKDPDEFIPERFVDSNVETK-GTSFELLPFGSGRRGC---PAMYVGLSTV- 456 Query: 337 THLLRNFEFELVSPFPENDWNA 272 E+ L + DW A Sbjct: 457 -------EYTLANLLYHFDWKA 471
>CP341_MOUSE (Q9JMA7) Cytochrome P450 3A41 (EC 1.14.14.1)| Length = 504 Score = 53.1 bits (126), Expect = 8e-07 Identities = 35/127 (27%), Positives = 58/127 (45%) Frame = -3 Query: 688 HDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFA 509 +D + EM+ L + LRL+P L R D + IPKG V Sbjct: 348 YDTVMEMEYLDMVLNETLRLYPIGNRLERFCKKDVELNG-----VYIPKGSTVMIPSYAL 402 Query: 508 NRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHL 329 + P + P+ + P+RF+ +E + Y+ FG G C+G FA++ +K T + Sbjct: 403 HHDPQHWPEPEEFQPERFS--KENKGSIDPYLYMPFGIGPRNCIGMRFAFMTMKLALTKV 460 Query: 328 LRNFEFE 308 ++NF F+ Sbjct: 461 MQNFSFQ 467
>CP17A_MESAU (P70687) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 511 Score = 52.8 bits (125), Expect = 1e-06 Identities = 34/121 (28%), Positives = 57/121 (47%), Gaps = 1/121 (0%) Frame = -3 Query: 664 VLYRCIKXALRLHPPLIMLL-RQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRLPHIF 488 +L I+ LR+ P ML+ +++SD S+ EF IPK V + + + Sbjct: 352 MLEATIREVLRIRPVAPMLIPHRANSDMSIG-----EFSIPKFTPVIINLWALHHSEKEW 406 Query: 487 KNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFE 308 PD + P+RF + + SY+ FG G C+GE A ++ HLL+ F+ + Sbjct: 407 DQPDRFMPERFLDPTGSHLITPSLSYLPFGAGARSCIGEVLARQELFLFMAHLLQRFDLD 466 Query: 307 L 305 + Sbjct: 467 V 467
>C76C1_ARATH (O64636) Cytochrome P450 76C1 (EC 1.14.-.-)| Length = 512 Score = 52.8 bits (125), Expect = 1e-06 Identities = 34/131 (25%), Positives = 63/131 (48%), Gaps = 1/131 (0%) Frame = -3 Query: 694 IDHDILAEMDVLYRCIKXALRLHPPLIMLL-RQSHSDFSVTTREGKEFDIPKGHIVATSP 518 ++ ++++ L +K RLH P+ +L+ R++ SD + F + K V + Sbjct: 351 VEESDISKLPYLQAVVKETFRLHTPVPLLIPRKAESDAEILG-----FMVLKDTQVLVNV 405 Query: 517 AFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIW 338 R P ++ NP ++P+RF G++ D + FG GR C G P A + + Sbjct: 406 WAIGRDPSVWDNPSQFEPERFL-GKDMDVRGRDYELTPFGAGRRICPGMPLAMKTVSLML 464 Query: 337 THLLRNFEFEL 305 LL +F+++L Sbjct: 465 ASLLYSFDWKL 475
>CP6B1_PAPPO (Q04552) Cytochrome P450 6B1 (EC 1.14.14.1) (CYPVIB1)| (CYP6B1V1/CYP6B1V2/ CYP6B1V3) Length = 498 Score = 52.8 bits (125), Expect = 1e-06 Identities = 43/161 (26%), Positives = 66/161 (40%), Gaps = 4/161 (2%) Frame = -3 Query: 694 IDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPA 515 I ++ L+EM L + LR +P R + +D+ G + I KG + S Sbjct: 344 ITYECLSEMTYLSKVFDETLRKYPVADFTQRNAKTDYVFP---GTDITIKKGQTIIVSTW 400 Query: 514 FANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWT 335 P + NP+ +DP+RF +D+ A Y+ F G CLG FA Q + Sbjct: 401 GIQNDPKYYPNPEKFDPERFNPENVKDRHPCA--YLPFSAGPRNCLGMRFAKWQSEVCIM 458 Query: 334 HLLRNFEFE----LVSPFPENDWNAMVVGIKGEVMVNYKRR 224 +L + E PF + + KG + VN RR Sbjct: 459 KVLSKYRVEPSMKSSGPFKFDPMRLFALP-KGGIYVNLVRR 498
>C28D1_DROME (Q9VMT5) Probable cytochrome P450 28d1 (EC 1.14.-.-) (CYPXXVIIID1)| Length = 502 Score = 52.8 bits (125), Expect = 1e-06 Identities = 40/159 (25%), Positives = 70/159 (44%), Gaps = 7/159 (4%) Frame = -3 Query: 679 LAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 500 ++E+ CI LR+ P++ + +T + G + G +V + Sbjct: 346 ISELPFTEACIHETLRIFSPVLAARKVVTEPCELTNKNGVSVKLRPGDVVIIPVNALHHD 405 Query: 499 PHIFKNPDSYDPDRFA---AGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHL 329 P ++ P S+ P+RF G ++ + G F FG G C G F+ QIKA + Sbjct: 406 PQYYEEPQSFKPERFLNINGGAKKYRDQGLF--FGFGDGPRICPGMRFSLTQIKAALVEI 463 Query: 328 LRNFEFELVSPFP----ENDWNAMVVGIKGEVMVNYKRR 224 +RNF+ + V+P E D + +KG V +++ R Sbjct: 464 VRNFDIK-VNPKTRKDNEIDDTYFMPALKGGVWLDFVER 501
>CP4P3_DROME (Q9V559) Probable cytochrome P450 4p3 (EC 1.14.-.-) (CYPIVP3)| Length = 515 Score = 52.8 bits (125), Expect = 1e-06 Identities = 40/152 (26%), Positives = 71/152 (46%), Gaps = 9/152 (5%) Frame = -3 Query: 649 IKXALRLHPPLIMLLRQSHSDFSVTTREGKEFD---IPKGHIVATSPAFANRLPHIFKNP 479 IK +RL P + + R+ TTRE + + +PKG + +R P + +P Sbjct: 378 IKETMRLFPSVPAMGRE-------TTRETELSNGLILPKGSQIFVHVFDIHRNPEYWDSP 430 Query: 478 DSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVS 299 + + P+RF +++ ++YI F G+ C+G+ FA ++K + LL+ F+ Sbjct: 431 EEFRPERFLPENSQNR--HTYAYIPFSAGQRNCIGQKFAMQEMKTLMVALLKQFQI---- 484 Query: 298 PFPENDWNAMV------VGIKGEVMVNYKRRK 221 PE D +V + K ++ V RRK Sbjct: 485 -LPEIDPKTIVFQTGLTLRTKNQIHVKLVRRK 515
>C71C1_MAIZE (Q43250) Cytochrome P450 71C1 (EC 1.14.-.-) (Benzoxazineless 4)| Length = 535 Score = 52.8 bits (125), Expect = 1e-06 Identities = 38/128 (29%), Positives = 59/128 (46%), Gaps = 3/128 (2%) Frame = -3 Query: 679 LAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 500 L+ M L IK ++R+HPP LL FS E + IP G V + R Sbjct: 372 LSRMPYLKATIKESMRIHPPAPFLLPH----FSTHDCEINGYTIPAGTRVIVNAWALARD 427 Query: 499 PHIFKNPDSYDPDRFAA-GR--EEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHL 329 P + + + P+RF GR E D ++ FG GR C G FA ++ + +L Sbjct: 428 PTCWDKAEEFFPERFLEQGRDAEVDMYGKDIRFVPFGAGRRICAGATFAIATVEIMLANL 487 Query: 328 LRNFEFEL 305 + +F++E+ Sbjct: 488 IYHFDWEM 495
>C71C4_MAIZE (Q43257) Cytochrome P450 71C4 (EC 1.14.-.-) (Benzoxazineless 2)| Length = 538 Score = 52.8 bits (125), Expect = 1e-06 Identities = 39/143 (27%), Positives = 65/143 (45%), Gaps = 3/143 (2%) Frame = -3 Query: 700 DKIDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATS 521 + + D L M L IK LRLHPP+ +LL +S+ E + IP V + Sbjct: 376 EMVTEDNLPGMTDLKAVIKETLRLHPPVPLLLPH----YSLDACEVAGYTIPANTRVVVN 431 Query: 520 PAFANRLPHIFKNPDSYDPDRFAAGREE---DKVAGAFSYISFGGGRHGCLGEPFAYLQI 350 R ++ + + P+RF +G D F +++FG GR C G A I Sbjct: 432 AWALGRHSGYWERENEFVPERFLSGDVAGGVDLKPNEFQFLAFGSGRRMCPGVHSASATI 491 Query: 349 KAIWTHLLRNFEFELVSPFPEND 281 +A+ ++L+ F+++L + D Sbjct: 492 EAMLSNLMYRFDWQLPAGMKAED 514
>C71E1_SORBI (O48958) Cytochrome P450 71E1 (EC 1.14.13.68)| (4-hydroxyphenylacetaldehyde oxime monooxygenase) Length = 531 Score = 52.8 bits (125), Expect = 1e-06 Identities = 37/140 (26%), Positives = 62/140 (44%), Gaps = 1/140 (0%) Frame = -3 Query: 697 KIDHDILAEMDVLYRCIKXALRLHPPLIMLL-RQSHSDFSVTTREGKEFDIPKGHIVATS 521 +++ + A++ L +K LRLHPP +L+ R++ D ++ +D+P V + Sbjct: 368 RVNSEDAAKIPYLKMVVKETLRLHPPATLLVPRETMRDTTIC-----GYDVPANTRVFVN 422 Query: 520 PAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAI 341 R P + PD ++PDRF G + D F I FG GR C G + Sbjct: 423 AWAIGRDPASWPAPDEFNPDRF-VGSDVDYYGSHFELIPFGAGRRICPGLTMGETNVTFT 481 Query: 340 WTHLLRNFEFELVSPFPEND 281 +LL +++ L D Sbjct: 482 LANLLYCYDWALPGAMKPED 501
>C11B1_RAT (P15393) Cytochrome P450 11B1, mitochondrial precursor (EC| 1.14.15.4) (CYPXIB1) (P450C11) (Steroid 11-beta-hydroxylase) (P450(11 beta)-DS) Length = 499 Score = 52.4 bits (124), Expect = 1e-06 Identities = 32/124 (25%), Positives = 59/124 (47%) Frame = -3 Query: 679 LAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 500 ++++ +L +K LRL+P + R HSD + + + +P G V R Sbjct: 358 MSDLPLLRAALKETLRLYPVGSFVERIVHSDLVL-----QNYHVPAGTFVIIYLYSMGRN 412 Query: 499 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 320 P +F P+ Y P R+ + +F +++FG G CLG A +++ + H+L+ Sbjct: 413 PAVFPRPERYMPQRWLERKR------SFQHLAFGFGVRQCLGRRLAEVEMLLLLHHMLKT 466 Query: 319 FEFE 308 F+ E Sbjct: 467 FQVE 470
>F3PH_PETHY (Q9SBQ9) Flavonoid 3'-monooxygenase (EC 1.14.13.21) (Flavonoid| 3'-hydroxylase) (Cytochrome P450 75B2) Length = 512 Score = 52.4 bits (124), Expect = 1e-06 Identities = 38/130 (29%), Positives = 60/130 (46%), Gaps = 3/130 (2%) Frame = -3 Query: 679 LAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 500 LA++ L +K RLHP + L + S+ + E + IPKG + + R Sbjct: 349 LAQLTYLEAIVKETFRLHPSTPLSLPRIASE----SCEINGYFIPKGSTLLLNVWAIARD 404 Query: 499 PHIFKNPDSYDPDRFAAGREEDKV---AGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHL 329 P+ + +P + P+RF G E+ KV F I FG GR C G ++ + L Sbjct: 405 PNAWADPLEFRPERFLPGGEKPKVDVRGNDFEVIPFGAGRRICAGMNLGIRMVQLMIATL 464 Query: 328 LRNFEFELVS 299 + F ++LVS Sbjct: 465 IHAFNWDLVS 474
>CP3AV_MESAU (O70537) Cytochrome P450 3A31 (EC 1.14.14.1) (CYPIIIA31) (P450| SH3A-1) Length = 501 Score = 52.4 bits (124), Expect = 1e-06 Identities = 38/128 (29%), Positives = 59/128 (46%), Gaps = 1/128 (0%) Frame = -3 Query: 688 HDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFA 509 +D + EM+ L + LRL+P L R D E +PKG IV P FA Sbjct: 345 YDKVMEMEYLDMVLNETLRLYPIGSRLERVCKQDV-----EMDGVFVPKGSIVMV-PVFA 398 Query: 508 NRL-PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTH 332 P + P+ + P+RF+ +E + ++ FG G C+G FA + +K T Sbjct: 399 LHYDPQYWPEPEKFRPERFS--KENKGSIDPYIFLPFGNGPRNCIGMRFALMNMKLALTK 456 Query: 331 LLRNFEFE 308 +L+NF + Sbjct: 457 VLQNFSLQ 464
>CP4X1_RAT (Q8K4D6) Cytochrome P450 4X1 (EC 1.14.14.1) (CYPIVX1)| Length = 507 Score = 52.4 bits (124), Expect = 1e-06 Identities = 40/120 (33%), Positives = 58/120 (48%), Gaps = 1/120 (0%) Frame = -3 Query: 679 LAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 500 L E+ CIK LRL PP+ + R+ +T +G +P G V S + Sbjct: 359 LDEIPYTTMCIKETLRLIPPIPSISRELSKP--LTLPDGHS--LPAGMTVVLSIWGLHHN 414 Query: 499 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIK-AIWTHLLR 323 P ++K+P +DP RF E + AF + F G C+G+ FA L++K AI LLR Sbjct: 415 PAVWKDPKVFDPLRFTKENSEQRHPCAF--LPFSSGPRNCIGQQFAMLELKVAIALTLLR 472
>CP52V_CANAP (P43083) Cytochrome P450 52E1 (EC 1.14.14.-) (CYPLIIE1)| Length = 519 Score = 52.4 bits (124), Expect = 1e-06 Identities = 45/144 (31%), Positives = 65/144 (45%), Gaps = 7/144 (4%) Frame = -3 Query: 679 LAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFD----IPKGHIVATSPAF 512 L + VL I+ LRLHP + + RQ+ D + T G D +PKG V S Sbjct: 359 LKQCKVLQNVIREVLRLHPNVPLNFRQAIVDTKLPTGGGPNGDQPVFVPKGQNVFYSTYS 418 Query: 511 ANRLPHIFKNPD--SYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIW 338 R I+ PD ++ PDR+ RE +A + YI F GG CLG+ FA + Sbjct: 419 MQRRTDIW-GPDATTFRPDRWNEPRE--ALASGWDYIPFNGGPRICLGQQFALTEASYTI 475 Query: 337 THLLRNF-EFELVSPFPENDWNAM 269 + + F E++ P N+M Sbjct: 476 VRICQEFSRIEVLHPDVITSKNSM 499
>CP51_ISSOR (Q02315) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (P450-14DM) (Fragment) Length = 414 Score = 52.4 bits (124), Expect = 1e-06 Identities = 38/129 (29%), Positives = 52/129 (40%), Gaps = 23/129 (17%) Frame = -3 Query: 697 KIDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSP 518 ++ +D L ++D++ IK LRLH PL + R+ D V + +PKGH V SP Sbjct: 288 ELTYDDLQKLDLVNATIKETLRLHMPLHSIFRKVTRDLPV---PNTSYIVPKGHYVLISP 344 Query: 517 AFANRLPHIFKNPDSYDPDR------------FAAGREEDK-----------VAGAFSYI 407 + F N + P R F A E K A Y+ Sbjct: 345 GYTMLSERYFPNASEFQPHRWDEIKSIDGGISFGAEGENAKETVDYGFGKISKGVASPYL 404 Query: 406 SFGGGRHGC 380 FGGGRH C Sbjct: 405 PFGGGRHRC 413
>CP11B_RANCA (Q92104) Cytochrome P450 11B, mitochondrial precursor (EC| 1.14.15.4) (CYPXIB) (P450C11) (Steroid 11-beta-hydroxylase) (P-450(11 beta,aldo)) Length = 517 Score = 52.4 bits (124), Expect = 1e-06 Identities = 36/130 (27%), Positives = 59/130 (45%) Frame = -3 Query: 688 HDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFA 509 + +L + +L IK LRL+P I + R D + + IP G +V Sbjct: 373 NQLLNSLPLLKGAIKETLRLYPVGITVQRHLIKDIVL-----HNYHIPAGTLVQVGLYPM 427 Query: 508 NRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHL 329 R P +F++ YDP R+ + + F ++FG G C+G A +I H+ Sbjct: 428 GRSPLLFQDALRYDPARWLKREDTN-----FKALAFGFGSRQCIGRRIAETEITLFLMHM 482 Query: 328 LRNFEFELVS 299 L+NF+ + VS Sbjct: 483 LKNFQIDTVS 492
>C11B1_CAVPO (Q64408) Cytochrome P450 11B1, mitochondrial precursor (EC| 1.14.15.4) (CYPXIB1) (P450C11) (Steroid 11-beta-hydroxylase) (Aldosterone synthase) Length = 500 Score = 52.0 bits (123), Expect = 2e-06 Identities = 31/119 (26%), Positives = 59/119 (49%) Frame = -3 Query: 673 EMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRLPH 494 E+ +L+ IK LR++P + L R F + + + IP G +V + R P Sbjct: 361 ELPLLWAAIKETLRMYPVGLFLER-----FLTSPLVLQNYHIPAGTLVHLNLYSMGRNPE 415 Query: 493 IFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNF 317 +F +P+ Y+P R+ +E + +++FG G C+G A +++ H+L++F Sbjct: 416 VFLSPEHYNPQRWLENKE------TYKHLAFGFGVRQCIGRRLAEVEMLLFLHHVLKSF 468
>CP6A9_DROME (Q27594) Cytochrome P450 6a9 (EC 1.14.-.-) (CYPVIA9)| Length = 504 Score = 52.0 bits (123), Expect = 2e-06 Identities = 33/131 (25%), Positives = 66/131 (50%) Frame = -3 Query: 697 KIDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSP 518 +I ++ + +M L + I LRL+ L +L R+ D+ V ++ I KG V Sbjct: 348 EITYESMKDMVYLDQVISETLRLYTVLPVLNRECLEDYEVPGHP--KYVIKKGMPVLIPC 405 Query: 517 AFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIW 338 +R ++ NP++++PD F+ R +++ + ++ FG G C+G F +Q ++ Sbjct: 406 GAMHRDEKLYANPNTFNPDNFSPERVKER--DSVEWLPFGDGPRNCIGMRFGQMQARSGL 463 Query: 337 THLLRNFEFEL 305 L+ F+F + Sbjct: 464 ALLINRFKFSV 474
>CP3AL_CALJA (O18993) Cytochrome P450 3A21 (EC 1.14.14.1) (CYPIIIA21) (P450| CM3A-10) Length = 503 Score = 52.0 bits (123), Expect = 2e-06 Identities = 35/128 (27%), Positives = 60/128 (46%), Gaps = 1/128 (0%) Frame = -3 Query: 688 HDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFA 509 +D + +M+ L + LRL P + L R D + IPKG +V P++A Sbjct: 347 YDTVLQMEYLDMVVNETLRLFPLAMRLERVCKKDVEING-----VFIPKG-VVVMIPSYA 400 Query: 508 NRL-PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTH 332 P + P+ + P+RF+ +++ + Y FG G C+G FA + +K Sbjct: 401 LHYDPKYWTEPEKFLPERFSKNNKDN--IDPYIYTPFGTGPRNCIGMRFALMNMKLALIR 458 Query: 331 LLRNFEFE 308 +L+NF F+ Sbjct: 459 VLQNFSFK 466
>CP51_MIMIV (Q5UQI3) Probable cytochrome P450 51 (EC 1.14.13.70) (CYPLI)| (P450-LIA1) (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (P450-14DM) Length = 709 Score = 51.6 bits (122), Expect = 2e-06 Identities = 25/60 (41%), Positives = 38/60 (63%) Frame = -3 Query: 493 IFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFE 314 ++ NP+SYDP RF A R E K +G +++G G H C G+ FA ++KA +++ NFE Sbjct: 390 VYANPNSYDPVRFMAPRNEPKDSG--HVMNWGKGVHECPGKQFAIYEVKAAIAYIVTNFE 447
>C71B5_ARATH (O65784) Cytochrome P450 71B5 (EC 1.14.-.-)| Length = 498 Score = 51.6 bits (122), Expect = 2e-06 Identities = 40/141 (28%), Positives = 64/141 (45%), Gaps = 1/141 (0%) Frame = -3 Query: 700 DKIDHDILAEMDVLYRCIKXALRLHPPLIMLL-RQSHSDFSVTTREGKEFDIPKGHIVAT 524 +KI + L +++ L I+ A RLHPP +LL R + SD ++ + + IPK ++ Sbjct: 338 EKITEEDLEKVEYLKMVIEEAFRLHPPAPLLLPRLTMSDINI-----QGYSIPKNTMIQI 392 Query: 523 SPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKA 344 + R P + PD + P+RF E K F + FG GR C G ++ Sbjct: 393 NTYTIGRDPKNWTKPDEFIPERFVDNPIEYK-GQHFELLPFGAGRRVCPGMATGITIVEL 451 Query: 343 IWTHLLRNFEFELVSPFPEND 281 LL F++ L + D Sbjct: 452 GLLSLLYFFDWSLPNGMTTKD 472
>C71B4_ARATH (O65786) Cytochrome P450 71B4 (EC 1.14.-.-)| Length = 504 Score = 51.6 bits (122), Expect = 2e-06 Identities = 37/132 (28%), Positives = 64/132 (48%), Gaps = 1/132 (0%) Frame = -3 Query: 697 KIDHDILAEMDVLYRCIKXALRLHPPLIMLL-RQSHSDFSVTTREGKEFDIPKGHIVATS 521 +I + L ++ L +K LRLHP +LL R++ +D + + +DIP+ + + Sbjct: 346 RIMEEDLDKLQYLKLVVKETLRLHPAAPLLLPRETMADIKI-----QGYDIPQKRALLVN 400 Query: 520 PAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAI 341 R P +KNP+ ++P+RF D +F + FG GR C G A I+ Sbjct: 401 AWSIGRDPESWKNPEEFNPERF-IDCPVDYKGHSFELLPFGSGRRICPGIAMAIATIELG 459 Query: 340 WTHLLRNFEFEL 305 +LL F++ + Sbjct: 460 LLNLLYFFDWNM 471
>CP7A1_MOUSE (Q64505) Cytochrome P450 7A1 (EC 1.14.13.17) (Cholesterol| 7-alpha-monooxygenase) (CYPVII) (Cholesterol 7-alpha-hydroxylase) Length = 503 Score = 51.6 bits (122), Expect = 2e-06 Identities = 41/138 (29%), Positives = 64/138 (46%), Gaps = 7/138 (5%) Frame = -3 Query: 694 IDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPA 515 +D + L + VL IK ALRL + + R + DF++ +G ++I K I+A P Sbjct: 335 LDQEQLNNLPVLDSIIKEALRLSSASLNI-RTAKEDFTLHLEDGS-YNIRKDDIIALYPQ 392 Query: 514 FANRLPHIFKNPDSYDPDRFAAGREEDKVAG-------AFSYISFGGGRHGCLGEPFAYL 356 + P I+ +P ++ DR+ + K + Y+ FG G C G FA Sbjct: 393 LMHLDPEIYPDPLTFKYDRYLDESGKAKTTFYRNGNKLKYFYMPFGSGATICPGRLFAVQ 452 Query: 355 QIKAIWTHLLRNFEFELV 302 +IK +L FE ELV Sbjct: 453 EIKQFLILMLSYFELELV 470
>C97B3_ARATH (O23365) Cytochrome P450 97B3 (EC 1.14.-.-)| Length = 580 Score = 51.6 bits (122), Expect = 2e-06 Identities = 34/153 (22%), Positives = 70/153 (45%), Gaps = 25/153 (16%) Frame = -3 Query: 688 HDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVT-----TREGKEFDIPKGHIVAT 524 ++ + +++ + + LRL P +L+R++ ++ +EG + +PKG + Sbjct: 400 YESMKKLEYIRLIVVEVLRLFPQPPLLIRRTLKPETLPGGHKGEKEGHK--VPKGTDIFI 457 Query: 523 SPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAG--------------------AFSYIS 404 S +R P+ + NP ++P+RF +E + + G F+++ Sbjct: 458 SVYNLHRSPYFWDNPHDFEPERFLRTKESNGIEGWAGFDPSRSPGALYPNEIIADFAFLP 517 Query: 403 FGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL 305 FGGG C+G+ FA ++ L + F+ EL Sbjct: 518 FGGGPRKCIGDQFALMESTVALAMLFQKFDVEL 550
>CP4Z1_HUMAN (Q86W10) Cytochrome P450 4Z1 (EC 1.14.14.1) (CYPIVZ1)| Length = 505 Score = 51.6 bits (122), Expect = 2e-06 Identities = 35/120 (29%), Positives = 63/120 (52%), Gaps = 1/120 (0%) Frame = -3 Query: 679 LAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 500 L++M CIK LRL+ P++ + R D +T +G+ +P G V + + Sbjct: 359 LSQMPYTTMCIKECLRLYAPVVNISRL--LDKPITFPDGR--SLPAGITVFINIWALHHN 414 Query: 499 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIK-AIWTHLLR 323 P+ +++P ++P RF+ RE + +++I F G C+G+ FA ++ K A+ LLR Sbjct: 415 PYFWEDPQVFNPLRFS--RENSEKIHPYAFIPFSAGLRNCIGQHFAIIECKVAVALTLLR 472
>CP6D5_DROME (Q9VFP1) Probable cytochrome P450 6d5 (EC 1.14.-.-) (CYPVID5)| Length = 508 Score = 51.6 bits (122), Expect = 2e-06 Identities = 36/131 (27%), Positives = 59/131 (45%) Frame = -3 Query: 697 KIDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSP 518 K+ +D +++M L CI R +P L +L R D+ V + I KG + S Sbjct: 354 KLTYDAISDMKYLEACILETARKYPALPLLNRICTKDYPVPD---SKLVIQKGTPIIISL 410 Query: 517 AFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIW 338 +R F +P +Y P+R+ E K +Y+ FG G C+G + +K Sbjct: 411 IGMHRDEEYFPDPLAYKPERYL---ENGKDYTQAAYLPFGEGPRMCIGARMGKVNVKIAI 467 Query: 337 THLLRNFEFEL 305 +L NF+ E+ Sbjct: 468 AKVLSNFDLEI 478
>CP52W_CANAP (Q12573) Cytochrome P450 52E2 (EC 1.14.14.-) (CYPLIIE2)| Length = 519 Score = 51.6 bits (122), Expect = 2e-06 Identities = 42/135 (31%), Positives = 63/135 (46%), Gaps = 7/135 (5%) Frame = -3 Query: 679 LAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFD----IPKGHIVATSPAF 512 L + VL I+ LRLHP + + R++ +D + T G D +PKG V + Sbjct: 359 LKQCKVLQNVIREVLRLHPNVPLNFREAIADTTFPTGGGPNGDQPIFVPKGQKVFYATYV 418 Query: 511 ANRLPHIFKNPDS--YDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIW 338 R I+ PDS + PDR+ RE +A + YI F GG CLG+ FA + Sbjct: 419 MQRNAGIW-GPDSTSFRPDRWNEPREA--LASGWDYIPFNGGPRICLGQQFALTEASYTL 475 Query: 337 THLLRNF-EFELVSP 296 + + F E++ P Sbjct: 476 VRICQEFSRIEVLHP 490
>C81D1_ARATH (Q9FG65) Cytochrome P450 81D1 (EC 1.14.-.-)| Length = 502 Score = 51.2 bits (121), Expect = 3e-06 Identities = 37/131 (28%), Positives = 63/131 (48%) Frame = -3 Query: 694 IDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPA 515 I+ L+E+ L + LRLHP +L+ S+ + G +D+P+G + + Sbjct: 346 IEEADLSELPYLKNIVLETLRLHPATPLLVPHMASE---DCKIGS-YDMPRGTTLLVNAW 401 Query: 514 FANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWT 335 +R P+ + +PDS+ P+RF E K+ ++FG GR C G A + Sbjct: 402 AIHRDPNTWDDPDSFKPERFEKEEEAQKL------LAFGLGRRACPGSGLAQRIVGLALG 455 Query: 334 HLLRNFEFELV 302 L++ FE+E V Sbjct: 456 SLIQCFEWERV 466
>C71BM_ARATH (Q9LTM1) Cytochrome P450 71B22 (EC 1.14.-.-)| Length = 500 Score = 51.2 bits (121), Expect = 3e-06 Identities = 33/110 (30%), Positives = 56/110 (50%), Gaps = 1/110 (0%) Frame = -3 Query: 700 DKIDHDILAEMDVLYRCIKXALRLHPPLIMLL-RQSHSDFSVTTREGKEFDIPKGHIVAT 524 +KI L ++ L I+ RLHPP +LL R++ SD + + ++IPK ++ Sbjct: 340 EKITEQDLEKVHYLKLVIEETFRLHPPAPLLLPRETMSDLKI-----QGYNIPKNTMIEI 394 Query: 523 SPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLG 374 + R P+ ++NP+ ++P+RF E K + + FG GR C G Sbjct: 395 NTYSIGRDPNCWENPNDFNPERFIDSPVEYK-GQHYELLPFGAGRRICPG 443
>C71D8_SOYBN (O81974) Cytochrome P450 71D8 (EC 1.14.-.-) (P450 CP7)| Length = 504 Score = 51.2 bits (121), Expect = 3e-06 Identities = 39/133 (29%), Positives = 57/133 (42%) Frame = -3 Query: 679 LAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 500 L E+ L IK LRLHPP ++ R+ + + ++IP V + R Sbjct: 351 LEELSYLKSVIKETLRLHPPSQLIPREC-----IISTNIDGYEIPIKTKVMINTWAIGRD 405 Query: 499 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 320 P + + D + P+RF + K +F YI FG GR C G F I LL + Sbjct: 406 PQYWSDADRFIPERFNDSSIDFK-GNSFEYIPFGAGRRMCPGMTFGLASITLPLALLLYH 464 Query: 319 FEFELVSPFPEND 281 F +EL + D Sbjct: 465 FNWELPNKMKPED 477
>C93B1_GLYEC (P93149) Cytochrome P450 93B1 (EC 1.14.13.87) (Licodione synthase)| ((2S)-flavanone 2-hydroxylase) (Flavone synthase II) (CYP GE-5) Length = 523 Score = 51.2 bits (121), Expect = 3e-06 Identities = 34/127 (26%), Positives = 61/127 (48%), Gaps = 5/127 (3%) Frame = -3 Query: 661 LYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRLPHIFKN 482 L +K RLHPP+ M+ R+ ++ +V + + IP+ ++ + R P + N Sbjct: 355 LQAILKETFRLHPPVPMVTRRCVAECTV-----ENYVIPEDSLLFVNVWSIGRNPKFWDN 409 Query: 481 PDSYDPDRFAAGREEDK----VAGA-FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNF 317 P + P+RF + V G+ F + FG GR C G A ++ A+ +++ F Sbjct: 410 PLEFRPERFLKLEGDSSGVVDVRGSHFQLLPFGSGRRMCPGVSLAMQEVPALLGAIIQCF 469 Query: 316 EFELVSP 296 +F +V P Sbjct: 470 DFHVVGP 476
>CP6L1_BLAGE (Q9GQM9) Cytochrome P450 6l1 (EC 1.14.-.-) (CYPVIL1)| Length = 503 Score = 51.2 bits (121), Expect = 3e-06 Identities = 32/130 (24%), Positives = 61/130 (46%) Frame = -3 Query: 697 KIDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSP 518 ++ ++ + +M L + LR +PP+ + R D+ + G + I KG + S Sbjct: 338 QVTYEGVKKMSYLDMVVSEVLRKYPPMSFIDRVCLHDYHIP---GTDVVIEKGTPIFVSL 394 Query: 517 AFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIW 338 +R + +P+ ++P+RF +E+ FSYI FG G C+G + +K + Sbjct: 395 LGLHRDSIFYPDPEDFNPERF--NKEKKSGVHPFSYIPFGDGPRNCIGLRLGLMSVKLVI 452 Query: 337 THLLRNFEFE 308 LL++ E Sbjct: 453 IMLLQSLRVE 462
>CP3A8_MACFA (P33268) Cytochrome P450 3A8 (EC 1.14.14.1) (CYPIIIA8) (P450-MKNF2)| (P-450-MK2) Length = 503 Score = 51.2 bits (121), Expect = 3e-06 Identities = 32/127 (25%), Positives = 56/127 (44%) Frame = -3 Query: 688 HDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFA 509 +D + +M+ L + LR+ P + L R D + IPKG +V Sbjct: 347 YDTVLQMEYLDMVVNETLRIFPIAMRLERVCKKDVEING-----IFIPKGVVVMIPSYAL 401 Query: 508 NRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHL 329 + P + P+ + P+RF+ ++ + Y FG G C+G FA + +K + Sbjct: 402 HHDPKYWPEPEKFLPERFSKKNNDN--IDPYIYTPFGSGPRNCIGMRFALMNMKLAIIRV 459 Query: 328 LRNFEFE 308 L+NF F+ Sbjct: 460 LQNFSFK 466
>C11B1_PAPHU (Q29527) Cytochrome P450 11B1, mitochondrial precursor (EC| 1.14.15.4) (CYPXIB1) (P450C11) (Steroid 11-beta-hydroxylase) Length = 503 Score = 51.2 bits (121), Expect = 3e-06 Identities = 34/125 (27%), Positives = 59/125 (47%) Frame = -3 Query: 673 EMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRLPH 494 E+ +L +K LRL+P + L R SD + + + IP G +V R P Sbjct: 361 ELPLLRAALKETLRLYPVGLFLERVVSSDLVL-----QNYHIPAGTLVRVFLYSLGRNPA 415 Query: 493 IFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFE 314 +F P+ Y+P R+ R + F ++ FG G CLG A ++ + H+L++ + Sbjct: 416 LFPRPERYNPQRWLDIRGSGR---NFYHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHLQ 472 Query: 313 FELVS 299 E ++ Sbjct: 473 VETLT 477
>C11B1_HUMAN (P15538) Cytochrome P450 11B1, mitochondrial precursor (EC| 1.14.15.4) (CYPXIB1) (P450C11) (P-450c11) (Steroid 11-beta-hydroxylase) Length = 503 Score = 51.2 bits (121), Expect = 3e-06 Identities = 34/125 (27%), Positives = 59/125 (47%) Frame = -3 Query: 673 EMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRLPH 494 E+ +L +K LRL+P + L R SD + + + IP G +V R P Sbjct: 361 ELPLLRAALKETLRLYPVGLFLERVVSSDLVL-----QNYHIPAGTLVRVFLYSLGRNPA 415 Query: 493 IFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFE 314 +F P+ Y+P R+ R + F ++ FG G CLG A ++ + H+L++ + Sbjct: 416 LFPRPERYNPQRWLDIRGSGR---NFYHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHLQ 472 Query: 313 FELVS 299 E ++ Sbjct: 473 VETLT 477
>C71B8_ARATH (P58048) Cytochrome P450 71B8 (EC 1.14.-.-)| Length = 506 Score = 51.2 bits (121), Expect = 3e-06 Identities = 38/133 (28%), Positives = 61/133 (45%), Gaps = 1/133 (0%) Frame = -3 Query: 700 DKIDHDILAEMDVLYRCIKXALRLHPPLIMLL-RQSHSDFSVTTREGKEFDIPKGHIVAT 524 ++I + L +++ L IK RLHPP LL RQ SD + + + IPK + Sbjct: 342 ERITEEDLEKVEYLKLVIKETFRLHPPGPFLLPRQVMSDIEI-----QGYHIPKNAHIKI 396 Query: 523 SPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKA 344 S R P + NP+ ++P+RFA K + + FG GR C G ++ Sbjct: 397 STYAIGRDPKCWTNPEEFNPERFANTSINYK-GQHYELLPFGAGRRSCPGMTLGITILEL 455 Query: 343 IWTHLLRNFEFEL 305 ++L F++ L Sbjct: 456 GLLNILYYFDWSL 468
>C4AC1_DROME (Q9VMS9) Probable cytochrome P450 4ac1 (EC 1.14.-.-) (CYPIVAC1)| Length = 509 Score = 51.2 bits (121), Expect = 3e-06 Identities = 32/112 (28%), Positives = 54/112 (48%) Frame = -3 Query: 649 IKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRLPHIFKNPDSY 470 IK +LR+ P + + RQ + V +PK ++ R P F PD + Sbjct: 372 IKESLRMFPSVPFIGRQCVEETVVNGMV-----MPKDTQISIHIYDIMRDPRHFPKPDLF 426 Query: 469 DPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFE 314 PDRF ++ F+Y+ F G+ C+G+ FA L++K + ++RNF+ Sbjct: 427 QPDRFLPENTVNR--HPFAYVPFSAGQRNCIGQKFAILEMKVLLAAVIRNFK 476
>C71BL_ARATH (Q9LTM2) Cytochrome P450 71B21 (EC 1.14.-.-)| Length = 499 Score = 50.8 bits (120), Expect = 4e-06 Identities = 34/110 (30%), Positives = 55/110 (50%), Gaps = 1/110 (0%) Frame = -3 Query: 700 DKIDHDILAEMDVLYRCIKXALRLHPPLIMLL-RQSHSDFSVTTREGKEFDIPKGHIVAT 524 +KI L ++ L I+ RLHPP +LL R++ SD + + ++IPK ++ Sbjct: 340 EKITEQDLEKVHYLKLVIQETFRLHPPAPLLLPRETMSDVKI-----QGYNIPKNTMIEI 394 Query: 523 SPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLG 374 + R P+ + NP+ + P+RF + K F + FGGGR C G Sbjct: 395 NTYAIGRDPNCWTNPNEFIPERFVDSPIDYK-GQHFELLPFGGGRRICPG 443
>C76C2_ARATH (O64637) Cytochrome P450 76C2 (EC 1.14.-.-)| Length = 512 Score = 50.8 bits (120), Expect = 4e-06 Identities = 35/131 (26%), Positives = 62/131 (47%), Gaps = 1/131 (0%) Frame = -3 Query: 694 IDHDILAEMDVLYRCIKXALRLHPPLIMLL-RQSHSDFSVTTREGKEFDIPKGHIVATSP 518 ++ ++ + L +K RLHP +L+ R++ SD V F +PK V + Sbjct: 352 VEESDISALPYLQAVVKETFRLHPAAPLLVPRKAESDVEVLG-----FMVPKDTQVFVNV 406 Query: 517 AFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIW 338 R P++++N + P+RF G++ D + FG GR C G P A + + Sbjct: 407 WAIGRDPNVWENSSRFKPERFL-GKDIDLRGRDYELTPFGAGRRICPGLPLAVKTVPLML 465 Query: 337 THLLRNFEFEL 305 LL +F+++L Sbjct: 466 ASLLYSFDWKL 476
>C71BU_ARATH (Q9SCN2) Cytochrome P450 71B31 (EC 1.14.-.-)| Length = 498 Score = 50.8 bits (120), Expect = 4e-06 Identities = 37/135 (27%), Positives = 64/135 (47%), Gaps = 1/135 (0%) Frame = -3 Query: 700 DKIDHDILAEMDVLYRCIKXALRLHPPLIMLL-RQSHSDFSVTTREGKEFDIPKGHIVAT 524 ++I + L +++ L IK + RLHPP +LL R++ SD + + + IPK V Sbjct: 340 ERITEEDLEKVEYLNLVIKESFRLHPPAPLLLPRETMSDIEI-----QGYHIPKNAHVKI 394 Query: 523 SPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKA 344 + R P + NP+ ++P+RF K + + FG GR C G ++ Sbjct: 395 NTYAIGRDPKRWTNPEEFNPERFLNTSINYK-GQHYELLPFGAGRRNCPGMTLGITILEL 453 Query: 343 IWTHLLRNFEFELVS 299 ++L F++ L S Sbjct: 454 GLLNILYYFDWSLPS 468
>C11B3_RAT (P30100) Cytochrome P450 11B3, mitochondrial precursor (EC| 1.14.15.4) (EC 1.14.15.5) (CYPXIB3) (P450-Aldo-2) (Aldosterone synthase) Length = 500 Score = 50.8 bits (120), Expect = 4e-06 Identities = 32/124 (25%), Positives = 60/124 (48%) Frame = -3 Query: 679 LAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 500 ++++ +L +K LRL+P L R +SD + + + +P G +V R Sbjct: 359 MSDLPLLRAALKETLRLYPVGGFLERILNSDLVL-----QNYHVPAGTLVLLYLYSMGRN 413 Query: 499 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 320 P +F P+ Y P R+ + +F +++FG G CLG A +++ + H+L+ Sbjct: 414 PAVFPRPERYMPQRWLERKR------SFQHLAFGFGVRQCLGRRLAEVEMLLLLHHMLKT 467 Query: 319 FEFE 308 F+ E Sbjct: 468 FQVE 471
>C11B2_MESAU (Q64658) Cytochrome P450 11B2, mitochondrial precursor (EC| 1.14.15.4) (EC 1.14.15.5) (C450XIB2) (Aldosterone synthase) (P-450Aldo) (ALDOS) (Aldosterone-synthesizing enzyme) (Steroid 18-hydroxylase) (P-450C18) Length = 500 Score = 50.8 bits (120), Expect = 4e-06 Identities = 33/124 (26%), Positives = 60/124 (48%) Frame = -3 Query: 679 LAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 500 ++++ +L +K LRL+P L R SD + + + +P G +V R Sbjct: 359 MSDLPLLRAVLKETLRLYPVGGFLERILSSDLVL-----QNYHVPAGTLVLLYLYSMGRN 413 Query: 499 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 320 P +F P+ Y P R+ G+F +++FG G CLG+ A +++ + H+L++ Sbjct: 414 PAVFPRPEHYLPQRWLERN------GSFQHLTFGFGVRQCLGKRLAQVEMLLLLHHVLKS 467 Query: 319 FEFE 308 F E Sbjct: 468 FRVE 471
>CP7A1_CRIGR (P46634) Cytochrome P450 7A1 (EC 1.14.13.17) (Cholesterol| 7-alpha-monooxygenase) (CYPVII) (Cholesterol 7-alpha-hydroxylase) Length = 504 Score = 50.8 bits (120), Expect = 4e-06 Identities = 41/138 (29%), Positives = 65/138 (47%), Gaps = 7/138 (5%) Frame = -3 Query: 694 IDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPA 515 +D L + VL IK ALRL + + R + DF++ +G ++I K I+A P Sbjct: 335 LDQIQLNNLPVLDSIIKEALRLSSASLNI-RTAKEDFTLHLEDGS-YNIRKDDIIALYPQ 392 Query: 514 FANRLPHIFKNPDSYDPDRFAAGREEDKVAG-------AFSYISFGGGRHGCLGEPFAYL 356 + P I+ +P ++ DR+ ++ K + + Y+ FG G C G FA Sbjct: 393 LMHLDPAIYPDPLTFKYDRYLDENKKAKTSFYSNGNKLKYFYMPFGSGATICPGRLFAVQ 452 Query: 355 QIKAIWTHLLRNFEFELV 302 +IK +L FE ELV Sbjct: 453 EIKQFLILMLSYFELELV 470
>C6A21_DROME (Q9V774) Probable cytochrome P450 6a21 (EC 1.14.-.-) (CYPVIA21)| Length = 504 Score = 50.8 bits (120), Expect = 4e-06 Identities = 30/131 (22%), Positives = 68/131 (51%) Frame = -3 Query: 697 KIDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSP 518 +++++ + ++ L + + LRL+ L +L R+ D+ V ++ I KG V Sbjct: 348 ELNYESMKDLVYLDQVVSETLRLYTVLPVLNRECLEDYEVPGHP--KYVIKKGMPVLIPC 405 Query: 517 AFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIW 338 +R ++ NP++++PD F+ R +++ + ++ FG G C+G F +Q + Sbjct: 406 GAMHRDEKLYANPNTFNPDNFSPERVKER--DSVEWLPFGDGPRNCIGMRFGQMQARIGL 463 Query: 337 THLLRNFEFEL 305 L+++F+F + Sbjct: 464 ALLIKDFKFSV 474
>C11B2_RAT (P30099) Cytochrome P450 11B2, mitochondrial precursor (EC| 1.14.15.4) (EC 1.14.15.5) (CYPXIB2) (P450-Aldo-1) (Aldosterone synthase) Length = 510 Score = 50.8 bits (120), Expect = 4e-06 Identities = 32/124 (25%), Positives = 60/124 (48%) Frame = -3 Query: 679 LAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 500 ++++ +L +K LRL+P L R +SD + + + +P G +V R Sbjct: 369 MSDLPLLRAALKETLRLYPVGGFLERILNSDLVL-----QNYHVPAGTLVLLYLYSMGRN 423 Query: 499 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 320 P +F P+ Y P R+ + +F +++FG G CLG A +++ + H+L+ Sbjct: 424 PAVFPRPERYMPQRWLERKR------SFQHLAFGFGVRQCLGRRLAEVEMLLLLHHMLKT 477 Query: 319 FEFE 308 F+ E Sbjct: 478 FQVE 481
>CP27A_RAT (P17178) Cytochrome P450 27, mitochondrial precursor (EC| 1.14.13.15) (Cytochrome P-450C27/25) (Sterol 26-hydroxylase) (Sterol 27-hydroxylase) (Vitamin D(3) 25-hydroxylase) (5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 27-hydroxylase) Length = 533 Score = 50.8 bits (120), Expect = 4e-06 Identities = 35/126 (27%), Positives = 57/126 (45%), Gaps = 2/126 (1%) Frame = -3 Query: 676 AEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRLP 497 A M +L IK LRL+P ++ + + E F PK +R P Sbjct: 383 AHMPLLKAVIKETLRLYP----VVPTNSRIITEKETEINGFLFPKNTQFVLCHYVVSRDP 438 Query: 496 HIFKNPDSYDPDRFAAGREEDK--VAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLR 323 +F P+S+ P R+ RE+D + F + FG G CLG A L+++ + + L++ Sbjct: 439 SVFPEPESFQPHRWLRKREDDNSGIQHPFGSVPFGYGVRSCLGRRIAELEMQLLLSRLIQ 498 Query: 322 NFEFEL 305 +E L Sbjct: 499 KYEVVL 504
>C71A9_SOYBN (O81970) Cytochrome P450 71A9 (EC 1.14.-.-) (P450 CP1)| Length = 499 Score = 50.4 bits (119), Expect = 5e-06 Identities = 36/125 (28%), Positives = 60/125 (48%) Frame = -3 Query: 679 LAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 500 L+++ + +K LRLHPP +L+ + ++ K F+IP V + Sbjct: 346 LSKLLYIKSVVKEVLRLHPPAPLLVPREITENCTI----KGFEIPAKTRVLVNAKSIAMD 401 Query: 499 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 320 P ++NP+ + P+RF + K F + FG GR GC G FA ++ +LL Sbjct: 402 PCCWENPNEFLPERFLVSPIDFK-GQHFEMLPFGVGRRGCPGVNFAMPVVELALANLLFR 460 Query: 319 FEFEL 305 F++EL Sbjct: 461 FDWEL 465
>C4AE1_DROME (O46054) Cytochrome P450 4ae1 (EC 1.14.-.-) (CYPIVAE1)| Length = 496 Score = 50.4 bits (119), Expect = 5e-06 Identities = 36/121 (29%), Positives = 57/121 (47%) Frame = -3 Query: 676 AEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRLP 497 A + L +K +LRL+PP+ + R D + E IP G V R Sbjct: 352 ATLPYLSCVVKESLRLYPPIPAVARCLEKDLVID-----EGYIPVGTNVVVLLWQLLRDE 406 Query: 496 HIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNF 317 IF +P + P+R EE +SYI F G C+G+ FA L++K + T ++R++ Sbjct: 407 AIFTDPLVFQPERHLG--EEAPRLSPYSYIPFSAGPRNCIGQKFALLEMKTMVTKVIRHY 464 Query: 316 E 314 + Sbjct: 465 Q 465
>CP6D2_DROME (Q9W223) Probable cytochrome P450 6d2 (EC 1.14.-.-) (CYPVID2)| Length = 512 Score = 50.4 bits (119), Expect = 5e-06 Identities = 44/163 (26%), Positives = 70/163 (42%), Gaps = 3/163 (1%) Frame = -3 Query: 700 DKIDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATS 521 D+ ++ + ++ L CI +R +P L L R+ D+ V G I KG + S Sbjct: 357 DRFTYEAVQDLKFLDICIMETIRKYPGLPFLNRECTEDYPVP---GTNHIIAKGTPILIS 413 Query: 520 PAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAI 341 R P F NP+ YDP RF + A +Y+ FG G C+ + K Sbjct: 414 LFGMQRDPVYFPNPNGYDPHRFDSNNMNYDQA---AYMPFGEGPRHCIALRMGKVNSKVA 470 Query: 340 WTHLLRNFEFELVSPFPENDWN---AMVVGIKGEVMVNYKRRK 221 +L NF+ + SP E ++ A V+ K + + +RK Sbjct: 471 VAKILANFDL-VQSPRKEVEFRFDAAPVLVTKEPLKLRLTKRK 512
>C71BF_ARATH (Q9LW27) Cytochrome P450 71B15 (EC 1.14.-.-)| Length = 490 Score = 50.4 bits (119), Expect = 5e-06 Identities = 35/133 (26%), Positives = 63/133 (47%), Gaps = 1/133 (0%) Frame = -3 Query: 700 DKIDHDILAEMDVLYRCIKXALRLHPPLIMLL-RQSHSDFSVTTREGKEFDIPKGHIVAT 524 ++I + L ++ +K LRLHP +LL RQ+ S + + +D+P + Sbjct: 339 ERIKEEDLNQLHYFKLVVKETLRLHPTTPLLLPRQTMSHIKI-----QGYDVPAKTQILV 393 Query: 523 SPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKA 344 + R P +++N D ++PDRF + K + +I FG GR C G + ++ Sbjct: 394 NVYAMGRDPKLWENADEFNPDRFLDSSVDFK-GKNYEFIPFGSGRRICPGMTMGTILVEM 452 Query: 343 IWTHLLRNFEFEL 305 +LL F++ L Sbjct: 453 ALLNLLYFFDWGL 465
>C98A2_SOYBN (O48922) Cytochrome P450 98A2 (EC 1.14.-.-)| Length = 509 Score = 50.4 bits (119), Expect = 5e-06 Identities = 36/115 (31%), Positives = 57/115 (49%), Gaps = 2/115 (1%) Frame = -3 Query: 655 RCI-KXALRLHPPL-IMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRLPHIFKN 482 +C+ K A+RLHPP +ML +++++ V +DIPKG V + R P ++K+ Sbjct: 352 QCVTKEAMRLHPPTPLMLPHRANANVKVGG-----YDIPKGSNVHVNVWAVARDPAVWKD 406 Query: 481 PDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNF 317 P + P+RF + D F + FG GR C G ++ HLL +F Sbjct: 407 PLEFRPERFLE-EDVDMKGHDFRLLPFGSGRRVCPGAQLGINLAASMLGHLLHHF 460
>C356_FUNHE (Q8AXY5) Cytochrome P450 3A56 (EC 1.14.14.1) (CYPIIIA56)| Length = 496 Score = 50.1 bits (118), Expect = 7e-06 Identities = 34/130 (26%), Positives = 60/130 (46%) Frame = -3 Query: 694 IDHDILAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPA 515 + + L EM+ L I +LRL P L R + + + IPK +V Sbjct: 344 VHYQPLMEMEYLDCVINESLRLFPIAARLERVAKAAVEING-----IVIPKDMVVMIPTW 398 Query: 514 FANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWT 335 +R P I+ P+++ P+RF+ +++ + Y+ FG G C+G FA + IK Sbjct: 399 PLHRDPEIWPEPEAFKPERFSKKNKDN--IDPYIYMPFGSGPRNCIGMRFALVLIKLAVV 456 Query: 334 HLLRNFEFEL 305 +L+ + F + Sbjct: 457 EILQQYSFSV 466
>CP7A1_RABIT (P51542) Cytochrome P450 7A1 (EC 1.14.13.17) (Cholesterol| 7-alpha-monooxygenase) (CYPVII) (Cholesterol 7-alpha-hydroxylase) Length = 501 Score = 50.1 bits (118), Expect = 7e-06 Identities = 39/133 (29%), Positives = 61/133 (45%), Gaps = 7/133 (5%) Frame = -3 Query: 679 LAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 500 L +M VL IK +LRL + + R + DF++ +G ++I K I+A P + Sbjct: 337 LNDMPVLDSIIKESLRLSSASLNI-RTAKEDFTLHLEDGS-YNIRKDDIIALYPQLMHLD 394 Query: 499 PHIFKNPDSYDPDRFAAGREEDKVAG-------AFSYISFGGGRHGCLGEPFAYLQIKAI 341 P I+ +P ++ DR+ + K + Y+ FG G C G FA +IK Sbjct: 395 PEIYPDPMTFKYDRYLDENRKTKTTFYSKGLKLKYYYMPFGSGATICPGRLFAIQEIKQF 454 Query: 340 WTHLLRNFEFELV 302 +L FE E V Sbjct: 455 LILMLSYFELEFV 467
>C71B2_ARATH (O65788) Cytochrome P450 71B2 (EC 1.14.-.-)| Length = 502 Score = 50.1 bits (118), Expect = 7e-06 Identities = 34/133 (25%), Positives = 63/133 (47%), Gaps = 1/133 (0%) Frame = -3 Query: 700 DKIDHDILAEMDVLYRCIKXALRLHPPLIMLL-RQSHSDFSVTTREGKEFDIPKGHIVAT 524 ++I + L +++ L +K RLHP L ++ R++ S + + +DIP + Sbjct: 343 ERITEEDLGKVEYLNHILKETFRLHPALPFVVPRETMSHIKI-----QGYDIPPKTQIQL 397 Query: 523 SPAFANRLPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKA 344 + R P + +P+ ++P+RFA D F + FG GR C G P A ++ Sbjct: 398 NVWTIGRDPKRWNDPEEFNPERFA-NSSVDFRGQHFDLLPFGSGRRICPGMPMAIASVEL 456 Query: 343 IWTHLLRNFEFEL 305 +LL F++ + Sbjct: 457 ALMNLLYYFDWSM 469
>C11B2_MOUSE (P15539) Cytochrome P450 11B2, mitochondrial precursor (EC| 1.14.15.4) (EC 1.14.15.5) (CYPXIB2) (P450C11) (Steroid 11-beta-hydroxylase) (Aldosterone synthase) Length = 500 Score = 50.1 bits (118), Expect = 7e-06 Identities = 32/124 (25%), Positives = 59/124 (47%) Frame = -3 Query: 679 LAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 500 ++++ +L +K LRL+P L R SD + + + +P G +V R Sbjct: 359 MSDLPLLKAALKETLRLYPVGGFLGRILSSDLVL-----QNYHVPAGTLVLLYLYSMGRN 413 Query: 499 PHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 320 P +F P+ Y P R+ + +F +++FG G CLG A +++ + H+L+ Sbjct: 414 PAVFPRPERYMPQRWLERKR------SFQHLAFGFGVRQCLGRRLAEVEMMLLLHHILKT 467 Query: 319 FEFE 308 F+ E Sbjct: 468 FQVE 471
>CP134_DROME (Q9VG40) Probable cytochrome P450 313a4 (EC 1.14.-.-)| (CYPCCCXIIIA4) Length = 478 Score = 50.1 bits (118), Expect = 7e-06 Identities = 34/128 (26%), Positives = 62/128 (48%), Gaps = 1/128 (0%) Frame = -3 Query: 673 EMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRLPH 494 +M L + ++R+ PP+ ++ RQ+ D ++ +PKG +A +R Sbjct: 332 QMVYLDLILNESMRVIPPVPVVSRQTSQDLKLSNG----IVVPKGVQIAIDIYHMHRSKK 387 Query: 493 IF-KNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNF 317 I+ + ++++PD F +DK ++YI F G C+G +A + K LLRN+ Sbjct: 388 IWGPDAETFNPDHFLPHNIQDK--HPYAYIPFTKGIRNCIGWRYALISAKVTLAKLLRNY 445 Query: 316 EFELVSPF 293 F+ PF Sbjct: 446 RFKTSFPF 453
>C6A18_DROME (Q9VB31) Probable cytochrome P450 6a18 (EC 1.14.-.-) (CYPVIA18)| Length = 507 Score = 50.1 bits (118), Expect = 7e-06 Identities = 39/152 (25%), Positives = 66/152 (43%), Gaps = 12/152 (7%) Frame = -3 Query: 658 YRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIP--------KGHIVATSPAFANR 503 Y CIK L + LR +V K F +P G V + + Sbjct: 353 YECIKDLKYLDQVINETLRHYTIVPNVDRVAAKRFVVPGNPKFVIEAGQSVIIPSSAIHH 412 Query: 502 LPHIFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLR 323 P I+ P+ + P+RF+ EE + +++ FG G C+G F +Q + L++ Sbjct: 413 DPSIYPEPNEFRPERFSP--EESAKRPSVAWLPFGEGPRNCIGLRFGQMQARIGLAMLIK 470 Query: 322 NFEFELVSPFPE----NDWNAMVVGIKGEVMV 239 NF F S P+ + +A+++GIKG + + Sbjct: 471 NFTFSPCSATPDPLTFDPHSAILLGIKGGIQL 502
>C75A5_EUSGR (Q96418) Flavonoid 3',5'-hydroxylase (EC 1.14.13.88) (F3'5'H)| (Cytochrome P450 75A5) Length = 510 Score = 50.1 bits (118), Expect = 7e-06 Identities = 37/129 (28%), Positives = 59/129 (45%), Gaps = 2/129 (1%) Frame = -3 Query: 679 LAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 500 ++++ L K A R HP + L + S E IPKG ++ + R Sbjct: 350 ISKLPYLQAICKEAFRKHPSTPLNLPRIASQAC----EVNGHYIPKGTRLSVNIWAIGRD 405 Query: 499 PHIFKNPDSYDPDRFAAGREE--DKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLL 326 P +++NP+ ++PDRF + D F I FG GR C G L ++ I L+ Sbjct: 406 PSLWENPNEFNPDRFLERKNAKIDPRGNDFELIPFGAGRRICAGTRLGILLVEYILGTLV 465 Query: 325 RNFEFELVS 299 +F++EL S Sbjct: 466 HSFDWELPS 474
>CP17A_SQUAC (Q92113) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 509 Score = 50.1 bits (118), Expect = 7e-06 Identities = 36/131 (27%), Positives = 63/131 (48%), Gaps = 1/131 (0%) Frame = -3 Query: 670 MDVLYRCIKXALRLHPPLIMLLRQ-SHSDFSVTTREGKEFDIPKGHIVATSPAFANRLPH 494 M+ L I LR+ P +L+ + +D S+ ++ IPKG V + + Sbjct: 353 MNFLNATIHEILRIQPVSPLLIPHVALADSSIG-----DYTIPKGTRVIINLWAIHHDEK 407 Query: 493 IFKNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFE 314 +KNPD++DP RF + + + SY+ FG G CLGE A +++ + +L+ F Sbjct: 408 EWKNPDAFDPGRFLDEDGKYVCSSSESYLPFGAGTRVCLGEMLARMELFLFTSWILQRFT 467 Query: 313 FELVSPFPEND 281 ++ +P D Sbjct: 468 VQVPPGYPPPD 478
>C79A2_ARATH (Q9FLC8) Cytochrome P450 79A2 (EC 1.-.-.-)| Length = 529 Score = 50.1 bits (118), Expect = 7e-06 Identities = 34/122 (27%), Positives = 52/122 (42%), Gaps = 1/122 (0%) Frame = -3 Query: 679 LAEMDVLYRCIKXALRLHPPLIMLLRQSHSDFSVTTREGKEFDIPKGHIVATSPAFANRL 500 L ++ + C+K A RLHP + H + T +G + IPKG V S R Sbjct: 371 LPNLNYVKACVKEAFRLHP--VAPFNLPHMSTTDTVVDG--YFIPKGSHVLISRMGIGRN 426 Query: 499 PHIFKNPDSYDPDR-FAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLR 323 P ++ P +DP+R + D + ISF GR GC+G + L++ Sbjct: 427 PSVWDKPHKFDPERHLSTNTCVDLNESDLNIISFSAGRRGCMGVDIGSAMTYMLLARLIQ 486 Query: 322 NF 317 F Sbjct: 487 GF 488 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 100,419,819 Number of Sequences: 219361 Number of extensions: 2103967 Number of successful extensions: 7185 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 6429 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 6695 length of database: 80,573,946 effective HSP length: 109 effective length of database: 56,663,597 effective search space used: 7026286028 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
