>NOTC3_HUMAN (Q9UM47) Neurogenic locus notch homolog protein 3 precursor (Notch 3)|
            [Contains: Notch 3 extracellular truncation; Notch 3
            intracellular domain]
          Length = 2321

 Score = 35.0 bits (79), Expect = 0.19
 Identities = 38/126 (30%), Positives = 46/126 (36%), Gaps = 4/126 (3%)
 Frame = -1

Query: 548  GPGHMQLPDWSTRPSAPTGSGRRQ*TAMCSCSTGAPGQALLLRLAEDNELP-RAAA*LEH 372
            GP    L DW +R     G    Q  A C C  G  G     RL +   LP R AA    
Sbjct: 994  GPQCQTLVDWCSRQPCQNGGRCVQTGAYCLCPPGWSG-----RLCDIRSLPCREAAAQIG 1048

Query: 371  QALRSYCVWVKPHWCEATGLELEQMKPHWCEGACLEPEQRQAA---STAAPCHCHPCSQG 201
              L           C+A G  +++   H+C   C  PE R  +       PC   PC  G
Sbjct: 1049 VRLEQL--------CQAGGQCVDEDSSHYC--VC--PEGRTGSHCEQEVDPCLAQPCQHG 1096

Query: 200  PPGNCR 183
              G CR
Sbjct: 1097 --GTCR 1100

>MEGF8_MOUSE (P60882) Multiple epidermal growth factor-like domains 8 (EGF-like|
            domain-containing protein 4) (Multiple EGF-like domain
            protein 4)
          Length = 2330

 Score = 31.6 bits (70), Expect = 2.0
 Identities = 16/38 (42%), Positives = 17/38 (44%), Gaps = 2/38 (5%)
 Frame = -1

Query: 287  WCEGACLEPEQRQAASTAAPCHCHPCSQGP--PGNCRR 180
            WC GACL  +Q        P    PCS  P  P  CRR
Sbjct: 1379 WCHGACLSGDQAHRLGCGVP----PCSPMPRSPEECRR 1412

>METE_PASMU (P57843) 5-methyltetrahydropteroyltriglutamate--homocysteine|
           methyltransferase (EC 2.1.1.14) (Methionine synthase,
           vitamin-B12 independent isozyme) (Cobalamin-independent
           methionine synthase)
          Length = 757

 Score = 30.4 bits (67), Expect = 4.6
 Identities = 12/25 (48%), Positives = 14/25 (56%)
 Frame = -3

Query: 591 KRVAWGHPACGLTARTWPHAAARLE 517
           K   W +P CGL  R WP   A+LE
Sbjct: 719 KERLWVNPDCGLKTRGWPETIAQLE 743

>MEGF8_HUMAN (Q7Z7M0) Multiple epidermal growth factor-like domains 8 (EGF-like|
            domain-containing protein 4) (Multiple EGF-like domain
            protein 4)
          Length = 2386

 Score = 30.4 bits (67), Expect = 4.6
 Identities = 16/38 (42%), Positives = 17/38 (44%), Gaps = 2/38 (5%)
 Frame = -1

Query: 287  WCEGACLEPEQRQAASTAAPCHCHPCSQGP--PGNCRR 180
            WC GACL  +Q         C   PCS  P  P  CRR
Sbjct: 1435 WCHGACLSGDQAHRLG----CGGSPCSPMPRSPEECRR 1468

>METE_SALTY (Q9L6N1) 5-methyltetrahydropteroyltriglutamate--homocysteine|
           methyltransferase (EC 2.1.1.14) (Methionine synthase,
           vitamin-B12 independent isozyme) (Cobalamin-independent
           methionine synthase)
          Length = 753

 Score = 30.0 bits (66), Expect = 6.0
 Identities = 11/28 (39%), Positives = 15/28 (53%)
 Frame = -3

Query: 579 WGHPACGLTARTWPHAAARLEHQAKRSY 496
           W +P CGL  R WP   A L +  K ++
Sbjct: 720 WVNPDCGLKTRGWPETRAALANMVKAAH 747

>METE_SALTI (Q8Z3B6) 5-methyltetrahydropteroyltriglutamate--homocysteine|
           methyltransferase (EC 2.1.1.14) (Methionine synthase,
           vitamin-B12 independent isozyme) (Cobalamin-independent
           methionine synthase)
          Length = 753

 Score = 30.0 bits (66), Expect = 6.0
 Identities = 11/28 (39%), Positives = 15/28 (53%)
 Frame = -3

Query: 579 WGHPACGLTARTWPHAAARLEHQAKRSY 496
           W +P CGL  R WP   A L +  K ++
Sbjct: 720 WVNPDCGLKTRGWPETRAALANMVKAAH 747

>METE_STRCO (Q93J59) 5-methyltetrahydropteroyltriglutamate--homocysteine|
           methyltransferase (EC 2.1.1.14) (Methionine synthase,
           vitamin-B12 independent isozyme) (Cobalamin-independent
           methionine synthase)
          Length = 772

 Score = 29.6 bits (65), Expect = 7.8
 Identities = 11/22 (50%), Positives = 13/22 (59%)
 Frame = -3

Query: 579 WGHPACGLTARTWPHAAARLEH 514
           W +P CGL  R WP   A LE+
Sbjct: 736 WVNPDCGLKTRGWPETRASLEN 757

>METE_STRAW (Q82LG4) 5-methyltetrahydropteroyltriglutamate--homocysteine|
           methyltransferase (EC 2.1.1.14) (Methionine synthase,
           vitamin-B12 independent isozyme) (Cobalamin-independent
           methionine synthase)
          Length = 772

 Score = 29.6 bits (65), Expect = 7.8
 Identities = 11/22 (50%), Positives = 13/22 (59%)
 Frame = -3

Query: 579 WGHPACGLTARTWPHAAARLEH 514
           W +P CGL  R WP   A LE+
Sbjct: 736 WVNPDCGLKTRGWPETRASLEN 757


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 94,288,650
Number of Sequences: 219361
Number of extensions: 1938019
Number of successful extensions: 5636
Number of sequences better than 10.0: 8
Number of HSP's better than 10.0 without gapping: 5179
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5631
length of database: 80,573,946
effective HSP length: 107
effective length of database: 57,102,319
effective search space used: 5881538857
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)