ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | rbags10e15 |
|---|---|
| Clone Library Name | barley_pub |
>CTR1_ARATH (Q05609) Serine/threonine-protein kinase CTR1 (EC 2.7.11.1)| Length = 821 Score = 226 bits (575), Expect = 6e-59 Identities = 105/150 (70%), Positives = 127/150 (84%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAG 497 MA DVAKG+NYLH NPPIVH DLK+PN+LVDK ++VKV DFGLSR KA+TF+SSKS AG Sbjct: 654 MAYDVAKGMNYLHNRNPPIVHRDLKSPNLLVDKKYTVKVCDFGLSRLKASTFLSSKSAAG 713 Query: 496 TPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQPWGGLGPAQVVGAVAFQNRRLPIP 317 TPEWMAPE LR EPSNEK DVYSFGVILWEL T+QQPWG L PAQVV AV F+ +RL IP Sbjct: 714 TPEWMAPEVLRDEPSNEKSDVYSFGVILWELATLQQPWGNLNPAQVVAAVGFKCKRLEIP 773 Query: 316 KDTIPELAALVESCWADDPRQRPSFSSIVD 227 ++ P++AA++E CW ++P +RPSF++I+D Sbjct: 774 RNLNPQVAAIIEGCWTNEPWKRPSFATIMD 803
>HT1_ARATH (Q2MHE4) Serine/threonine-protein kinase HT1 (EC 2.7.11.1) (High| leaf temperature protein 1) Length = 390 Score = 135 bits (340), Expect = 1e-31 Identities = 67/150 (44%), Positives = 96/150 (64%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVA 500 R+ALD+++G+ YLH ++H DLK+ N+L++ VKV DFG S + T +K Sbjct: 191 RLALDISRGMEYLHSQG--VIHRDLKSNNLLLNDEMRVKVADFGTSCLE-TQCREAKGNM 247 Query: 499 GTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQPWGGLGPAQVVGAVAFQNRRLPI 320 GT WMAPE ++ +P K DVYSFG++LWEL T P+ G+ P Q AVA +N R P+ Sbjct: 248 GTYRWMAPEMIKEKPYTRKVDVYSFGIVLWELTTALLPFQGMTPVQAAFAVAEKNERPPL 307 Query: 319 PKDTIPELAALVESCWADDPRQRPSFSSIV 230 P P LA L++ CW+++P +RP FS+IV Sbjct: 308 PASCQPALAHLIKRCWSENPSKRPDFSNIV 337
>MLTK_MOUSE (Q9ESL4) Mitogen-activated protein kinase kinase kinase MLT (EC| 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper-and sterile alpha motif kinase ZAK) (Sterile alpha motif- and leucine zipper-containing kinase AZK) ( Length = 802 Score = 126 bits (317), Expect = 5e-29 Identities = 65/149 (43%), Positives = 91/149 (61%), Gaps = 1/149 (0%) Frame = -1 Query: 673 ALDVAKGINYLHCXNP-PIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAG 497 A DVAKG++YLH P ++H DLK+ N+++ + +K+ DFG SRF T + S+ G Sbjct: 111 ATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASRFHNHT--THMSLVG 168 Query: 496 TPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQPWGGLGPAQVVGAVAFQNRRLPIP 317 T WMAPE ++ P +E CD YS+GV+LWE+LT + P+ GL QV V +N RL IP Sbjct: 169 TFPWMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAWLVVEKNERLTIP 228 Query: 316 KDTIPELAALVESCWADDPRQRPSFSSIV 230 A L+ CW D ++RPSF I+ Sbjct: 229 SSCPRSFAELLHQCWEADAKKRPSFKQII 257
>MLTK_HUMAN (Q9NYL2) Mitogen-activated protein kinase kinase kinase MLT (EC| 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper-and sterile alpha motif-containing kinase) (Sterile alpha motif- and leucine zipper-containing kinase Length = 800 Score = 126 bits (317), Expect = 5e-29 Identities = 65/149 (43%), Positives = 91/149 (61%), Gaps = 1/149 (0%) Frame = -1 Query: 673 ALDVAKGINYLHCXNP-PIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAG 497 A DVAKG++YLH P ++H DLK+ N+++ + +K+ DFG SRF T + S+ G Sbjct: 111 ATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASRFHNHT--THMSLVG 168 Query: 496 TPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQPWGGLGPAQVVGAVAFQNRRLPIP 317 T WMAPE ++ P +E CD YS+GV+LWE+LT + P+ GL QV V +N RL IP Sbjct: 169 TFPWMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAWLVVEKNERLTIP 228 Query: 316 KDTIPELAALVESCWADDPRQRPSFSSIV 230 A L+ CW D ++RPSF I+ Sbjct: 229 SSCPRSFAELLHQCWEADAKKRPSFKQII 257
>M3K12_MOUSE (Q60700) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 888 Score = 122 bits (305), Expect = 1e-27 Identities = 61/148 (41%), Positives = 89/148 (60%) Frame = -1 Query: 673 ALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAGT 494 ++ +A G+NYLH I+H DLK+PNML+ + VK+ DFG S+ + + + S AGT Sbjct: 250 SMGIAGGMNYLHLHK--IIHRDLKSPNMLITYDDVVKISDFGTSK-ELSDKSTKMSFAGT 306 Query: 493 PEWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQPWGGLGPAQVVGAVAFQNRRLPIPK 314 WMAPE +R EP +EK D++SFGV+LWELLT + P+ + + ++ V + LP+P Sbjct: 307 VAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSAIIWGVGSNSLHLPVPS 366 Query: 313 DTIPELAALVESCWADDPRQRPSFSSIV 230 L+ CW PR RPSF I+ Sbjct: 367 SCPDGFKILLRQCWNSKPRNRPSFRQIL 394
>M3K12_HUMAN (Q12852) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 859 Score = 122 bits (305), Expect = 1e-27 Identities = 61/148 (41%), Positives = 89/148 (60%) Frame = -1 Query: 673 ALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAGT 494 ++ +A G+NYLH I+H DLK+PNML+ + VK+ DFG S+ + + + S AGT Sbjct: 217 SMGIAGGMNYLHLHK--IIHRDLKSPNMLITYDDVVKISDFGTSK-ELSDKSTKMSFAGT 273 Query: 493 PEWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQPWGGLGPAQVVGAVAFQNRRLPIPK 314 WMAPE +R EP +EK D++SFGV+LWELLT + P+ + + ++ V + LP+P Sbjct: 274 VAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSAIIWGVGSNSLHLPVPS 333 Query: 313 DTIPELAALVESCWADDPRQRPSFSSIV 230 L+ CW PR RPSF I+ Sbjct: 334 SCPDGFKILLRQCWNSKPRNRPSFRQIL 361
>M3K12_RAT (Q63796) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 888 Score = 121 bits (303), Expect = 2e-27 Identities = 61/148 (41%), Positives = 89/148 (60%) Frame = -1 Query: 673 ALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAGT 494 ++ +A G+NYLH I+H DLK+PNML+ + VK+ DFG S+ + + + S AGT Sbjct: 250 SMGIAGGMNYLHLHK--IIHRDLKSPNMLITYDDVVKISDFGTSK-ELSDKSTKMSFAGT 306 Query: 493 PEWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQPWGGLGPAQVVGAVAFQNRRLPIPK 314 WMAPE +R EP +EK D++SFGV+LWELLT + P+ + + ++ V + LP+P Sbjct: 307 VAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSAIIWGVGSNSLHLPVPS 366 Query: 313 DTIPELAALVESCWADDPRQRPSFSSIV 230 L+ CW PR RPSF I+ Sbjct: 367 SCPDGFKILLRQCWNRKPRNRPSFRQIL 394
>KYK1_DICDI (P18160) Non-receptor tyrosine kinase spore lysis A (EC 2.7.10.2)| (Tyrosine-protein kinase 1) Length = 1584 Score = 120 bits (302), Expect = 3e-27 Identities = 61/163 (37%), Positives = 92/163 (56%), Gaps = 13/163 (7%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWS-------------VKVGDFGLSR 539 ++ALD+AKG+NYLH PPI+H DL + N+L+D N K+ DFGLSR Sbjct: 1394 KLALDIAKGMNYLHGWTPPILHRDLSSRNILLDHNIDPKNPVVSSRQDIKCKISDFGLSR 1453 Query: 538 FKATTFISSKSVAGTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQPWGGLGPAQV 359 K G +MAPE +G+ ++EK DVYS+G++L+ELLT +P + P ++ Sbjct: 1454 LKKEQASQMTQSVGCIPYMAPEVFKGDSNSEKSDVYSYGMVLFELLTSDEPQQDMKPMKM 1513 Query: 358 VGAVAFQNRRLPIPKDTIPELAALVESCWADDPRQRPSFSSIV 230 A+++ R PIP T + ++ CW +P RP+F I+ Sbjct: 1514 AHLAAYESYRPPIPLTTSSKWKEILTQCWDSNPDSRPTFKQII 1556
>YR831_MIMIV (Q7T6Y2) Putative serine/threonine-protein kinase/receptor R831| precursor (EC 2.7.11.1) Length = 1624 Score = 117 bits (293), Expect = 3e-26 Identities = 60/150 (40%), Positives = 89/150 (59%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVA 500 ++ A GI+YLH NP IVH D+K N+LVD++++VK+ DFG +R K ++ + Sbjct: 1464 KLLYGAAMGIDYLHSSNPMIVHRDIKPANILVDEHFNVKIADFGFARIKEDN--TTMTRC 1521 Query: 499 GTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQPWGGLGPAQVVGAVAFQNRRLPI 320 GTP W APE +RGE EK DV+SFGV++WE+LT ++P+ V + R I Sbjct: 1522 GTPCWTAPEVIRGEKYCEKADVFSFGVVMWEVLTGKEPFAECN-FMKVSLDILEGGRPII 1580 Query: 319 PKDTIPELAALVESCWADDPRQRPSFSSIV 230 P D E A L++ CW +RP+ + +V Sbjct: 1581 PSDCPHEFAKLIKKCWHAKAHKRPTMTEVV 1610 Score = 112 bits (280), Expect = 1e-24 Identities = 62/158 (39%), Positives = 92/158 (58%), Gaps = 8/158 (5%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFI--SSKS 506 +MA +KG+++LH IVH DLK+ N+L+D W+VKV DFGL++ K+ ++ + Sbjct: 887 KMAYQASKGMHFLHSSG--IVHRDLKSLNLLLDSKWNVKVSDFGLTKVKSELDKKKTNDN 944 Query: 505 VAGTPEWMAPEFLRGEPSNEK--CDVYSFGVILWELLTMQQPWGGLGPAQVVGAVAFQNR 332 + GT W+APE L + DVYSFG+ILWELLT +QP+ G+ PA + +V Sbjct: 945 IIGTIHWIAPEILNDSTEVDYILADVYSFGIILWELLTREQPYKGMTPAAIAVSVIRDGM 1004 Query: 331 RLPIPKDTIP----ELAALVESCWADDPRQRPSFSSIV 230 R PI + + E L++ CW D RP+F I+ Sbjct: 1005 RPPISDEAVTAHSIEYIDLIKQCWHSDTIIRPTFLEIM 1042
>M3K13_HUMAN (O43283) Mitogen-activated protein kinase kinase kinase 13 (EC| 2.7.11.25) (Mixed lineage kinase) (MLK) (Leucine zipper-bearing kinase) Length = 966 Score = 117 bits (292), Expect = 4e-26 Identities = 59/141 (41%), Positives = 85/141 (60%) Frame = -1 Query: 664 VAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAGTPEW 485 +A G+NYLH I+H DLK+PN+LV +VK+ DFG S+ + + + S AGT W Sbjct: 263 IASGMNYLHLHK--IIHRDLKSPNVLVTHTDAVKISDFGTSK-ELSDKSTKMSFAGTVAW 319 Query: 484 MAPEFLRGEPSNEKCDVYSFGVILWELLTMQQPWGGLGPAQVVGAVAFQNRRLPIPKDTI 305 MAPE +R EP +EK D++SFGV+LWELLT + P+ + + ++ V + LP+P Sbjct: 320 MAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSAIIWGVGSNSLHLPVPSTCP 379 Query: 304 PELAALVESCWADDPRQRPSF 242 L++ W PR RPSF Sbjct: 380 DGFKILMKQTWQSKPRNRPSF 400
>M3K13_PONPY (Q5R8X7) Mitogen-activated protein kinase kinase kinase 13 (EC| 2.7.11.25) Length = 966 Score = 115 bits (289), Expect = 9e-26 Identities = 58/141 (41%), Positives = 85/141 (60%) Frame = -1 Query: 664 VAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAGTPEW 485 +A G+NYLH I+H DLK+PN+LV +VK+ DFG S+ + + + S AGT W Sbjct: 263 IASGMNYLHLHK--IIHRDLKSPNVLVTHTDAVKISDFGTSK-ELSDKSTKMSFAGTVAW 319 Query: 484 MAPEFLRGEPSNEKCDVYSFGVILWELLTMQQPWGGLGPAQVVGAVAFQNRRLPIPKDTI 305 +APE +R EP +EK D++SFGV+LWELLT + P+ + + ++ V + LP+P Sbjct: 320 LAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSAIIWGVGSNSLHLPVPSTCP 379 Query: 304 PELAALVESCWADDPRQRPSF 242 L++ W PR RPSF Sbjct: 380 DGFKILMKQTWQSKPRNRPSF 400
>M3K9_HUMAN (P80192) Mitogen-activated protein kinase kinase kinase 9 (EC| 2.7.11.25) (Mixed lineage kinase 1) Length = 1104 Score = 115 bits (288), Expect = 1e-25 Identities = 66/158 (41%), Positives = 92/158 (58%), Gaps = 9/158 (5%) Frame = -1 Query: 673 ALDVAKGINYLHCXN-PPIVHWDLKTPNMLVDK--------NWSVKVGDFGLSRFKATTF 521 A+ +A+G+NYLH PI+H DLK+ N+L+ + N +K+ DFGL+R T Sbjct: 246 AVQIARGMNYLHDEAIVPIIHRDLKSSNILILQKVENGDLSNKILKITDFGLAREWHRT- 304 Query: 520 ISSKSVAGTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQPWGGLGPAQVVGAVAF 341 + S AGT WMAPE +R ++ DV+S+GV+LWELLT + P+ G+ V VA Sbjct: 305 -TKMSAAGTYAWMAPEVIRASMFSKGSDVWSYGVLLWELLTGEVPFRGIDGLAVAYGVAM 363 Query: 340 QNRRLPIPKDTIPELAALVESCWADDPRQRPSFSSIVD 227 LPIP A L+E CW DP RPSF++I+D Sbjct: 364 NKLALPIPSTCPEPFAKLMEDCWNPDPHSRPSFTNILD 401
>M3K11_HUMAN (Q16584) Mitogen-activated protein kinase kinase kinase 11 (EC| 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline-rich kinase) Length = 847 Score = 114 bits (285), Expect = 3e-25 Identities = 63/157 (40%), Positives = 93/157 (59%), Gaps = 9/157 (5%) Frame = -1 Query: 673 ALDVAKGINYLHCXN-PPIVHWDLKTPNMLV--------DKNWSVKVGDFGLSRFKATTF 521 A+ +A+G++YLHC P++H DLK+ N+L+ ++ ++K+ DFGL+R T Sbjct: 219 AVQIARGMHYLHCEALVPVIHRDLKSNNILLLQPIESDDMEHKTLKITDFGLAREWHKT- 277 Query: 520 ISSKSVAGTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQPWGGLGPAQVVGAVAF 341 + S AGT WMAPE ++ ++ DV+SFGV+LWELLT + P+ G+ V VA Sbjct: 278 -TQMSAAGTYAWMAPEVIKASTFSKGSDVWSFGVLLWELLTGEVPYRGIDCLAVAYGVAV 336 Query: 340 QNRRLPIPKDTIPELAALVESCWADDPRQRPSFSSIV 230 LPIP A L+ CWA DP +RP F+SI+ Sbjct: 337 NKLTLPIPSTCPEPFAQLMADCWAQDPHRRPDFASIL 373
>M3KSL_DROME (Q95UN8) Mitogen-activated protein kinase kinase kinase (EC| 2.7.11.25) (Mixed lineage kinase) (dMLK) (Protein slipper) Length = 1161 Score = 110 bits (276), Expect = 3e-24 Identities = 62/157 (39%), Positives = 88/157 (56%), Gaps = 9/157 (5%) Frame = -1 Query: 673 ALDVAKGINYLHCXNP-PIVHWDLKTPNMLVDK--------NWSVKVGDFGLSRFKATTF 521 A+ +A+G+NYLH P I+H DLK+ N+L+ + ++K+ DFGL+R T Sbjct: 242 AIQIARGMNYLHNEAPMSIIHRDLKSSNVLIYEAIEGNHLQQKTLKITDFGLAREMYNT- 300 Query: 520 ISSKSVAGTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQPWGGLGPAQVVGAVAF 341 S AGT WM PE + ++ DV+S+GV+LWEL+T + P+ G P V VA Sbjct: 301 -QRMSAAGTYAWMPPEVISVSTYSKFSDVWSYGVLLWELITGETPYKGFDPLSVAYGVAV 359 Query: 340 QNRRLPIPKDTIPELAALVESCWADDPRQRPSFSSIV 230 LPIPK AL++SCW DP +RP F I+ Sbjct: 360 NTLTLPIPKTCPETWGALMKSCWQTDPHKRPGFKEIL 396
>M3K10_HUMAN (Q02779) Mitogen-activated protein kinase kinase kinase 10 (EC| 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST) Length = 954 Score = 110 bits (276), Expect = 3e-24 Identities = 66/157 (42%), Positives = 89/157 (56%), Gaps = 9/157 (5%) Frame = -1 Query: 673 ALDVAKGINYLHCXNP-PIVHWDLKTPNMLVDK--------NWSVKVGDFGLSRFKATTF 521 A+ VA+G+NYLH P PI+H DLK+ N+L+ + + +K+ DFGL+R T Sbjct: 200 AVQVARGMNYLHNDAPVPIIHRDLKSINILILEAIENHNLADTVLKITDFGLAREWHKT- 258 Query: 520 ISSKSVAGTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQPWGGLGPAQVVGAVAF 341 + S AGT WMAPE +R ++ DV+SFGV+LWELLT + P+ + V VA Sbjct: 259 -TKMSAAGTYAWMAPEVIRLSLFSKSSDVWSFGVLLWELLTGEVPYREIDALAVAYGVAM 317 Query: 340 QNRRLPIPKDTIPELAALVESCWADDPRQRPSFSSIV 230 LPIP A L+E CW DP RP F SI+ Sbjct: 318 NKLTLPIPSTCPEPFARLLEECWDPDPHGRPDFGSIL 354
>RIPK2_HUMAN (O43353) Receptor-interacting serine/threonine-protein kinase 2 (EC| 2.7.11.1) (RIP-like-interacting CLARP kinase) (Receptor-interacting protein 2) (RIP-2) (CARD-containing interleukin-1 beta-converting enzyme-associated kinase) (CARD-containi Length = 540 Score = 106 bits (264), Expect = 7e-23 Identities = 61/162 (37%), Positives = 99/162 (61%), Gaps = 16/162 (9%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVA 500 R+ ++A G+NYLH PP++H DLKT N+L+D + VK+ DFGLS+++ + S+S Sbjct: 123 RILHEIALGVNYLHNMTPPLLHHDLKTQNILLDNEFHVKIADFGLSKWRMMSLSQSRSSK 182 Query: 499 GTPE-----WMAPE-FLRGEPSNE--KCDVYSFGVILWELLTMQQPWGGL-GPAQVVGAV 347 PE +M PE + G+ S K D+YS+ VI WE+L+ +QP+ + P Q++ +V Sbjct: 183 SAPEGGTIIYMPPENYEPGQKSRASIKHDIYSYAVITWEVLSRKQPFEDVTNPLQIMYSV 242 Query: 346 AFQNRRLPIPKDTIP-------ELAALVESCWADDPRQRPSF 242 + Q R I ++++P + +L+ES WA +P +RPSF Sbjct: 243 S-QGHRPVINEESLPYDIPHRARMISLIESGWAQNPDERPSF 283
>RIPK2_MOUSE (P58801) Receptor-interacting serine/threonine-protein kinase 2 (EC| 2.7.11.1) Length = 539 Score = 105 bits (263), Expect = 1e-22 Identities = 60/162 (37%), Positives = 100/162 (61%), Gaps = 16/162 (9%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVA 500 R+ ++A G+NYLH NPP++H DLKT N+L+D + VK+ DFGLS+++ + S+S Sbjct: 123 RILHEIALGVNYLHNMNPPLLHHDLKTQNILLDNEFHVKIADFGLSKWRMMSLSQSRSYK 182 Query: 499 GTPE-----WMAPE-FLRGEPS--NEKCDVYSFGVILWELLTMQQPWGGL-GPAQVVGAV 347 PE +M PE + G+ S + K D+YS+ VI+WE+L+ +QP+ + P Q++ +V Sbjct: 183 SAPEGGTIIYMPPENYEPGQKSRASVKHDIYSYAVIMWEVLSRKQPFEEVTNPLQIMYSV 242 Query: 346 AFQNRRLPIPKDTIP-------ELAALVESCWADDPRQRPSF 242 + Q R ++ +P + +L++S WA +P +RPSF Sbjct: 243 S-QGHRPDTSEENLPFDIPHRGLMISLIQSGWAQNPDERPSF 283
>M3KL4_HUMAN (Q5TCX8) Mitogen-activated protein kinase kinase kinase (EC| 2.7.11.25) (Mixed lineage kinase 4) Length = 1036 Score = 104 bits (260), Expect = 2e-22 Identities = 61/158 (38%), Positives = 91/158 (57%), Gaps = 9/158 (5%) Frame = -1 Query: 673 ALDVAKGINYLHCXN-PPIVHWDLKTPNMLVDK--------NWSVKVGDFGLSRFKATTF 521 A+ +A+G+ YLH PI+H DLK+ N+L+ + N ++K+ DFGL+R T Sbjct: 241 AVQIARGMLYLHEEAFVPILHRDLKSSNILLLEKIEHDDICNKTLKITDFGLAREWHRT- 299 Query: 520 ISSKSVAGTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQPWGGLGPAQVVGAVAF 341 + S AGT WMAPE ++ ++ D++S+GV+LWELLT + P+ G+ V VA Sbjct: 300 -TKMSTAGTYAWMAPEVIKSSLFSKGSDIWSYGVLLWELLTGEVPYRGIDGLAVAYGVAV 358 Query: 340 QNRRLPIPKDTIPELAALVESCWADDPRQRPSFSSIVD 227 LPIP A L++ CW DP RPSF+ I++ Sbjct: 359 NKLTLPIPSTCPEPFAKLMKECWQQDPHIRPSFALILE 396
>KYK2_DICDI (P18161) Tyrosine-protein kinase 2 (EC 2.7.10.2) (Fragment)| Length = 410 Score = 103 bits (256), Expect = 6e-22 Identities = 59/154 (38%), Positives = 87/154 (56%), Gaps = 3/154 (1%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVA 500 +MA D+A G+ +LH IVH DL + N+L+D+ ++K+ DFGLS K+ + + Sbjct: 211 KMATDMALGLLHLHSIT--IVHRDLTSQNILLDELGNIKISDFGLSAEKSREGSMTMTNG 268 Query: 499 G--TPEWMAPEFLRGEPS-NEKCDVYSFGVILWELLTMQQPWGGLGPAQVVGAVAFQNRR 329 G P W PE + +EK DVY F +++WE+LT + P+ L +Q VA+ R Sbjct: 269 GICNPRWRPPELTKNLGHYSEKVDVYCFSLVVWEILTGEIPFSDLDGSQRSAQVAYAGLR 328 Query: 328 LPIPKDTIPELAALVESCWADDPRQRPSFSSIVD 227 PIP+ PEL L+ CW DP RP F+ IV+ Sbjct: 329 PPIPEYCDPELKLLLTQCWEADPNDRPPFTYIVN 362
>M3K7_HUMAN (O43318) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1) Length = 606 Score = 102 bits (255), Expect = 8e-22 Identities = 57/150 (38%), Positives = 87/150 (58%), Gaps = 3/150 (2%) Frame = -1 Query: 670 LDVAKGINYLHCXNPP-IVHWDLKTPNMLVDKNWSV-KVGDFGLSRFKATTFISSKSVAG 497 L ++G+ YLH P ++H DLK PN+L+ +V K+ DFG + T ++K G Sbjct: 135 LQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLKICDFGTACDIQTHMTNNK---G 191 Query: 496 TPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQPWGGL-GPAQVVGAVAFQNRRLPI 320 + WMAPE G +EKCDV+S+G+ILWE++T ++P+ + GPA + R P+ Sbjct: 192 SAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFRIMWAVHNGTRPPL 251 Query: 319 PKDTIPELAALVESCWADDPRQRPSFSSIV 230 K+ + +L+ CW+ DP QRPS IV Sbjct: 252 IKNLPKPIESLMTRCWSKDPSQRPSMEEIV 281
>M3K7_MOUSE (Q62073) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1) Length = 579 Score = 102 bits (255), Expect = 8e-22 Identities = 57/150 (38%), Positives = 87/150 (58%), Gaps = 3/150 (2%) Frame = -1 Query: 670 LDVAKGINYLHCXNPP-IVHWDLKTPNMLVDKNWSV-KVGDFGLSRFKATTFISSKSVAG 497 L ++G+ YLH P ++H DLK PN+L+ +V K+ DFG + T ++K G Sbjct: 135 LQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLKICDFGTACDIQTHMTNNK---G 191 Query: 496 TPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQPWGGL-GPAQVVGAVAFQNRRLPI 320 + WMAPE G +EKCDV+S+G+ILWE++T ++P+ + GPA + R P+ Sbjct: 192 SAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFRIMWAVHNGTRPPL 251 Query: 319 PKDTIPELAALVESCWADDPRQRPSFSSIV 230 K+ + +L+ CW+ DP QRPS IV Sbjct: 252 IKNLPKPIESLMTRCWSKDPSQRPSMEEIV 281
>ANKK1_MOUSE (Q8BZ25) Ankyrin repeat and protein kinase domain-containing| protein 1 (EC 2.7.11.1) Length = 745 Score = 99.4 bits (246), Expect = 9e-21 Identities = 53/160 (33%), Positives = 89/160 (55%), Gaps = 11/160 (6%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATT----FISS 512 R+ + + +N+LH PP++H DLK N+L+D N VK+ DFGLS++ + +I Sbjct: 134 RIIHETSLAMNFLHSIKPPLLHLDLKPGNILLDNNMHVKISDFGLSKWMEQSTQKQYIER 193 Query: 511 KSVAGTPEWMAPEFL--RGEPSNEKCDVYSFGVILWELLTMQQPWGGLGPAQVVGAVAFQ 338 ++ GT ++ PE + + DVYSF +++WE+LT ++P+ GL ++ VA Sbjct: 194 SALRGTLSYIPPEMFLENNKAPGPEYDVYSFAIVIWEILTQKKPYAGLNMMTIIIRVAAG 253 Query: 337 NR-RLPIPKDTIPE----LAALVESCWADDPRQRPSFSSI 233 R L D PE + L++ CW DP++RP F ++ Sbjct: 254 MRPSLQDVSDEWPEEVHQMVNLMKRCWDQDPKKRPCFLNV 293
>M3K7_DROME (Q9V3Q6) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (TGF-beta-activated kinase 1) (dTAK1) Length = 678 Score = 99.0 bits (245), Expect = 1e-20 Identities = 51/150 (34%), Positives = 84/150 (56%), Gaps = 2/150 (1%) Frame = -1 Query: 673 ALDVAKGINYLHCXNP-PIVHWDLKTPNMLV-DKNWSVKVGDFGLSRFKATTFISSKSVA 500 A A+G+ YLH P P++H D+K N+L+ +K ++K+ DFG K+T +++ Sbjct: 118 ARQCAEGLAYLHAMTPKPLIHRDVKPLNLLLTNKGRNLKICDFGTVADKSTMMTNNR--- 174 Query: 499 GTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQPWGGLGPAQVVGAVAFQNRRLPI 320 G+ WMAPE G EKCD++S+ ++LWE+L+ +QP+ G+ A + ++ R P+ Sbjct: 175 GSAAWMAPEVFEGSKYTEKCDIFSWAIVLWEVLSRKQPFKGIDNAYTIQWKIYKGERPPL 234 Query: 319 PKDTIPELAALVESCWADDPRQRPSFSSIV 230 + L+ +CW P RPS IV Sbjct: 235 LTTCPKRIEDLMTACWKTVPEDRPSMQYIV 264
>ANKK1_HUMAN (Q8NFD2) Ankyrin repeat and protein kinase domain-containing| protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288) Length = 765 Score = 97.1 bits (240), Expect = 4e-20 Identities = 55/160 (34%), Positives = 88/160 (55%), Gaps = 11/160 (6%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATT----FISS 512 R+ + + +N+LH PP++H DLK N+L+D N VK+ DFGLS++ + +I Sbjct: 122 RIIHETSLAMNFLHSIKPPLLHLDLKPGNILLDSNMHVKISDFGLSKWMEQSTRMQYIER 181 Query: 511 KSVAGTPEWMAPE-FLRGEPS-NEKCDVYSFGVILWELLTMQQPWGGLGPAQVVGAVAFQ 338 ++ G ++ PE FL + K DVYSF +++WELLT ++P+ G ++ VA Sbjct: 182 SALRGMLSYIPPEMFLESNKAPGPKYDVYSFAIVIWELLTQKKPYSGFNMMMIIIRVAAG 241 Query: 337 NR-RLPIPKDTIP----ELAALVESCWADDPRQRPSFSSI 233 R L D P ++ L++ CW DP++RP F I Sbjct: 242 MRPSLQPVSDQWPSEAQQMVDLMKRCWDQDPKKRPCFLDI 281
>MIPR_LYMST (Q25410) Putative molluscan insulin-related peptide(s) receptor| precursor (EC 2.7.10.1) [Contains: Putative molluscan insulin-related peptide(s) receptor alpha chain; Putative molluscan insulin-related peptide(s) receptor beta chain] Length = 1607 Score = 95.1 bits (235), Expect = 2e-19 Identities = 55/154 (35%), Positives = 89/154 (57%), Gaps = 3/154 (1%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVA 500 +MA ++A G+ YL + VH DL N +V + +VK+GDFG++R T K Sbjct: 1152 QMAGEIADGMAYL--ADKKFVHRDLAARNCMVSEERTVKIGDFGMTRDIYETDYYRKGGK 1209 Query: 499 GT--PEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRR 329 G WMAPE L+ DV+S+GV++WE++T+ QP+ GL +VV ++ Sbjct: 1210 GMLPVRWMAPESLKDGVFTSLSDVWSYGVVMWEMVTLAAQPYQGLSNEEVVKFIS-DGYI 1268 Query: 328 LPIPKDTIPELAALVESCWADDPRQRPSFSSIVD 227 + +P++ E+A L++ CWA P QRP+F +I++ Sbjct: 1269 MELPENCPNEMAYLMQHCWAKKPNQRPTFKAIIE 1302
>TNI3K_RAT (Q7TQP6) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 834 Score = 93.6 bits (231), Expect = 5e-19 Identities = 56/151 (37%), Positives = 82/151 (54%), Gaps = 2/151 (1%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRF-KATTFISSKSVA 500 +A+DVAKG+ YLH PI+H DL + N+L+ ++ V DFG SRF ++ + Sbjct: 565 IAVDVAKGMEYLHSLTQPIIHRDLNSHNILLYEDGHAVVADFGESRFLQSLDEDNMTKQP 624 Query: 499 GTPEWMAPE-FLRGEPSNEKCDVYSFGVILWELLTMQQPWGGLGPAQVVGAVAFQNRRLP 323 G WMAPE F + K DV+S+ + LWELLT + P+ L PA +A+ + R P Sbjct: 625 GNLRWMAPEVFTQCTRYTIKADVFSYSLCLWELLTGEIPFAHLKPAAAAADMAYHHIRPP 684 Query: 322 IPKDTIPELAALVESCWADDPRQRPSFSSIV 230 I +++L+ W P RP FS +V Sbjct: 685 IGYSIPKPISSLLIRGWNACPEGRPEFSEVV 715
>INSRR_CAVPO (P14617) Insulin receptor-related protein precursor (EC 2.7.10.1)| (IRR) (IR-related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain] Length = 1300 Score = 93.2 bits (230), Expect = 6e-19 Identities = 58/155 (37%), Positives = 88/155 (56%), Gaps = 3/155 (1%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVA 500 +MA ++A G+ YL VH DL N +V ++++VK+GDFG++R T K Sbjct: 1094 QMAGEIADGMAYLAANK--FVHRDLAARNCMVSQDFTVKIGDFGMTRDVYETDYYRKGGK 1151 Query: 499 GT--PEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRR 329 G WMAPE L+ DV+SFGV+LWE++T+ +QP+ GL QV+ V Sbjct: 1152 GLLPVRWMAPESLKDGIFTTHSDVWSFGVVLWEIVTLAEQPYQGLSNEQVLKFV-MDGGV 1210 Query: 328 LPIPKDTIPELAALVESCWADDPRQRPSFSSIVDT 224 L +D +L L+ SCW +PR RP+F+ I+++ Sbjct: 1211 LEELEDCPHQLQELMSSCWQQNPRLRPTFTQILNS 1245
>INSR_XENLA (Q9PVZ4) Insulin receptor precursor (EC 2.7.10.1) (IR) (Xe-InsR)| (XTK-1b) [Contains: Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1362 Score = 93.2 bits (230), Expect = 6e-19 Identities = 55/154 (35%), Positives = 87/154 (56%), Gaps = 3/154 (1%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVA 500 +MA +++ G+ YL+ VH DL N +V +++VK+GDFG++R T K Sbjct: 1127 QMAAEISDGMAYLNAKK--FVHRDLAARNCMVADDYAVKIGDFGMTRDIYETDYYRKGGK 1184 Query: 499 GT--PEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRR 329 G WM+PE L+ DV+SFGV+LWE+ ++ +QP+ GL QV+ V Sbjct: 1185 GLLPVRWMSPESLKDGVFTAFSDVWSFGVVLWEITSLAEQPYQGLSNEQVLKFV-MDGGS 1243 Query: 328 LPIPKDTIPELAALVESCWADDPRQRPSFSSIVD 227 L P++ P L +L++ CW +P+ RP+F I+D Sbjct: 1244 LDHPENCPPRLHSLMQMCWQYNPKMRPTFLEIID 1277
>FRK_HUMAN (P42685) Tyrosine-protein kinase FRK (EC 2.7.10.2) (Nuclear| tyrosine protein kinase RAK) Length = 505 Score = 92.8 bits (229), Expect = 8e-19 Identities = 56/153 (36%), Positives = 88/153 (57%), Gaps = 5/153 (3%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSR-FKATT---FISSK 509 MA VA G+ YL N +H DL N+LV ++ KV DFGL+R FK + S Sbjct: 334 MAAQVASGMAYLESRN--YIHRDLAARNVLVGEHNIYKVADFGLARVFKVDNEDIYESRH 391 Query: 508 SVAGTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNR 332 + +W APE +R + K DV+SFG++L+E++T + P+ G+ AQV+ +A QN Sbjct: 392 EIKLPVKWTAPEAIRSNKFSIKSDVWSFGILLYEIITYGKMPYSGMTGAQVIQMLA-QNY 450 Query: 331 RLPIPKDTIPELAALVESCWADDPRQRPSFSSI 233 RLP P + + ++ CW +P++RP+F ++ Sbjct: 451 RLPQPSNCPQQFYNIMLECWNAEPKERPTFETL 483
>INSRR_HUMAN (P14616) Insulin receptor-related protein precursor (EC 2.7.10.1)| (IRR) (IR-related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain] Length = 1297 Score = 92.4 bits (228), Expect = 1e-18 Identities = 59/160 (36%), Positives = 88/160 (55%), Gaps = 8/160 (5%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVA 500 +MA ++A G+ YL VH DL N +V ++++VK+GDFG++R T K Sbjct: 1094 QMAGEIADGMAYLAANK--FVHRDLAARNCMVSQDFTVKIGDFGMTRDVYETDYYRKGGK 1151 Query: 499 GT--PEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVV-----GAVA 344 G WMAPE L+ DV+SFGV+LWE++T+ +QP+ GL QV+ G V Sbjct: 1152 GLLPVRWMAPESLKDGIFTTHSDVWSFGVVLWEIVTLAEQPYQGLSNEQVLKFVMDGGVL 1211 Query: 343 FQNRRLPIPKDTIPELAALVESCWADDPRQRPSFSSIVDT 224 + P+ +L L+ CW +PR RPSF+ I+D+ Sbjct: 1212 EELEGCPL------QLQELMSRCWQPNPRLRPSFTHILDS 1245
>TNI3K_HUMAN (Q59H18) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 936 Score = 92.0 bits (227), Expect = 1e-18 Identities = 55/151 (36%), Positives = 82/151 (54%), Gaps = 2/151 (1%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRF-KATTFISSKSVA 500 +A+DVAKG+ YLH PI+H DL + N+L+ ++ V DFG SRF ++ + Sbjct: 667 IAVDVAKGMEYLHNLTQPIIHRDLNSHNILLYEDGHAVVADFGESRFLQSLDEDNMTKQP 726 Query: 499 GTPEWMAPE-FLRGEPSNEKCDVYSFGVILWELLTMQQPWGGLGPAQVVGAVAFQNRRLP 323 G WMAPE F + K DV+S+ + LWE+LT + P+ L PA +A+ + R P Sbjct: 727 GNLRWMAPEVFTQCTRYTIKADVFSYALCLWEILTGEIPFAHLKPAAAAADMAYHHIRPP 786 Query: 322 IPKDTIPELAALVESCWADDPRQRPSFSSIV 230 I +++L+ W P RP FS +V Sbjct: 787 IGYSIPKPISSLLIRGWNACPEGRPEFSEVV 817
>WNK1_RAT (Q9JIH7) Serine/threonine-protein kinase WNK1 (EC 2.7.11.1)| (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) Length = 2126 Score = 92.0 bits (227), Expect = 1e-18 Identities = 53/148 (35%), Positives = 81/148 (54%), Gaps = 2/148 (1%) Frame = -1 Query: 664 VAKGINYLHCXNPPIVHWDLKTPNMLV-DKNWSVKVGDFGLSRFKATTFISSKSVAGTPE 488 + KG+ +LH PPI+H DLK N+ + SVK+GD GL+ K +F +KSV GTPE Sbjct: 331 ILKGLQFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASF--AKSVIGTPE 388 Query: 487 WMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQPWGGL-GPAQVVGAVAFQNRRLPIPKD 311 +MAPE E +E DVY+FG+ + E+ T + P+ AQ+ V + K Sbjct: 389 FMAPEMYE-EKYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFDKV 447 Query: 310 TIPELAALVESCWADDPRQRPSFSSIVD 227 IPE+ ++E C + +R S +++ Sbjct: 448 AIPEVKEIIEGCIRQNKDERYSIKDLLN 475
>RIPK4_HUMAN (P57078) Receptor-interacting serine/threonine-protein kinase 4 (EC| 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase) Length = 832 Score = 92.0 bits (227), Expect = 1e-18 Identities = 50/157 (31%), Positives = 84/157 (53%), Gaps = 11/157 (7%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTF---ISSK 509 R+ + A G+N+LHC PP++H DLK N+L+D ++ VK+ DFGL++ + +S Sbjct: 120 RIIHETAVGMNFLHCMAPPLLHLDLKPANILLDAHYHVKISDFGLAKCNGLSHSHDLSMD 179 Query: 508 SVAGTPEWMAPEFLRGEPS--NEKCDVYSFGVILWELLTMQQPWGGLGPAQVVGAVAFQN 335 + GT ++ PE +R + + K DVYSF +++W +LT ++P+ + + Sbjct: 180 GLFGTIAYLPPERIREKSRLFDTKHDVYSFAIVIWGVLTQKKPFADEKNILHIMVKVVKG 239 Query: 334 RRLPIP------KDTIPELAALVESCWADDPRQRPSF 242 R +P L L++ CW DPR RP+F Sbjct: 240 HRPELPPVCRARPRACSHLIRLMQRCWQGDPRVRPTF 276
>ACK2_BOVIN (O02742) Activated CDC42 kinase 2 (EC 2.7.10.2) (ACK-2)| Length = 747 Score = 92.0 bits (227), Expect = 1e-18 Identities = 52/155 (33%), Positives = 80/155 (51%), Gaps = 4/155 (2%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATT---FISSK 509 R A+ VA+G+ YL +H DL N+L+ VK+GDFGL R ++ + Sbjct: 231 RYAVQVAEGMGYLEAKR--FIHRDLAARNLLLATRDLVKIGDFGLMRALPQNDDHYVMQE 288 Query: 508 SVAGTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNR 332 W APE L+ + D + FGV LWE+ T Q+PW GL +Q++ + + Sbjct: 289 HRKVPFAWCAPESLKTRTFSHASDTWMFGVTLWEMFTYGQEPWIGLNGSQILHKIDKEGE 348 Query: 331 RLPIPKDTIPELAALVESCWADDPRQRPSFSSIVD 227 RLP P+D ++ ++ CWA P RP+F ++ D Sbjct: 349 RLPRPEDCPQDIYNVMVQCWAHKPEDRPTFVALRD 383
>WNK1_HUMAN (Q9H4A3) Serine/threonine-protein kinase WNK1 (EC 2.7.11.1)| (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein) Length = 2382 Score = 92.0 bits (227), Expect = 1e-18 Identities = 53/148 (35%), Positives = 81/148 (54%), Gaps = 2/148 (1%) Frame = -1 Query: 664 VAKGINYLHCXNPPIVHWDLKTPNMLV-DKNWSVKVGDFGLSRFKATTFISSKSVAGTPE 488 + KG+ +LH PPI+H DLK N+ + SVK+GD GL+ K +F +KSV GTPE Sbjct: 331 ILKGLQFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASF--AKSVIGTPE 388 Query: 487 WMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQPWGGL-GPAQVVGAVAFQNRRLPIPKD 311 +MAPE E +E DVY+FG+ + E+ T + P+ AQ+ V + K Sbjct: 389 FMAPEMYE-EKYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFDKV 447 Query: 310 TIPELAALVESCWADDPRQRPSFSSIVD 227 IPE+ ++E C + +R S +++ Sbjct: 448 AIPEVKEIIEGCIRQNKDERYSIKDLLN 475
>WNK1_MOUSE (P83741) Serine/threonine-protein kinase WNK1 (EC 2.7.11.1)| (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) Length = 2377 Score = 92.0 bits (227), Expect = 1e-18 Identities = 53/148 (35%), Positives = 81/148 (54%), Gaps = 2/148 (1%) Frame = -1 Query: 664 VAKGINYLHCXNPPIVHWDLKTPNMLV-DKNWSVKVGDFGLSRFKATTFISSKSVAGTPE 488 + KG+ +LH PPI+H DLK N+ + SVK+GD GL+ K +F +KSV GTPE Sbjct: 331 ILKGLQFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASF--AKSVIGTPE 388 Query: 487 WMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQPWGGL-GPAQVVGAVAFQNRRLPIPKD 311 +MAPE E +E DVY+FG+ + E+ T + P+ AQ+ V + K Sbjct: 389 FMAPEMYE-EKYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFDKV 447 Query: 310 TIPELAALVESCWADDPRQRPSFSSIVD 227 IPE+ ++E C + +R S +++ Sbjct: 448 AIPEVKEIIEGCIRQNKDERYSIKDLLN 475
>TNI3K_MOUSE (Q5GIG6) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 833 Score = 91.7 bits (226), Expect = 2e-18 Identities = 55/151 (36%), Positives = 81/151 (53%), Gaps = 2/151 (1%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRF-KATTFISSKSVA 500 +A+DVAKG+ YLH PI+H DL + N+L+ ++ V DFG SRF ++ + Sbjct: 564 IAVDVAKGMEYLHSLTQPIIHRDLNSHNILLYEDGHAVVADFGESRFLQSLDEDNMTKQP 623 Query: 499 GTPEWMAPE-FLRGEPSNEKCDVYSFGVILWELLTMQQPWGGLGPAQVVGAVAFQNRRLP 323 G WMAPE F + K DV+S+ + LWELL + P+ L PA +A+ + R P Sbjct: 624 GNLRWMAPEVFTQCTRYTIKADVFSYALCLWELLIGEIPFAHLKPAAAAADMAYHHIRPP 683 Query: 322 IPKDTIPELAALVESCWADDPRQRPSFSSIV 230 I +++L+ W P RP FS +V Sbjct: 684 IGYSIPKPISSLLMRGWNACPEGRPEFSEVV 714
>ACK1_HUMAN (Q07912) Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine| kinase non-receptor protein 2) Length = 1036 Score = 91.7 bits (226), Expect = 2e-18 Identities = 52/155 (33%), Positives = 80/155 (51%), Gaps = 4/155 (2%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATT---FISSK 509 R A+ VA+G+ YL +H DL N+L+ VK+GDFGL R ++ + Sbjct: 231 RYAVQVAEGMGYLESKR--FIHRDLAARNLLLATRDLVKIGDFGLMRALPQNDDHYVMQE 288 Query: 508 SVAGTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNR 332 W APE L+ + D + FGV LWE+ T Q+PW GL +Q++ + + Sbjct: 289 HRKVPFAWCAPESLKTRTFSHASDTWMFGVTLWEMFTYGQEPWIGLNGSQILHKIDKEGE 348 Query: 331 RLPIPKDTIPELAALVESCWADDPRQRPSFSSIVD 227 RLP P+D ++ ++ CWA P RP+F ++ D Sbjct: 349 RLPRPEDCPQDIYNVMVQCWAHKPEDRPTFVALRD 383
>M3LK7_DROME (P83104) Putative mitogen-activated protein kinase kinase kinase| 7-like (EC 2.7.11.25) Length = 393 Score = 91.3 bits (225), Expect = 2e-18 Identities = 59/157 (37%), Positives = 87/157 (55%), Gaps = 8/157 (5%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLV-DKNWSVKVGDFGLSRFKATTFISSKS- 506 R AL AK + YLH + PIVH D+K NML+ +++ +K+ DFGL AT ++K+ Sbjct: 110 RWALQCAKALAYLHSLDRPIVHRDIKPQNMLLYNQHEDLKICDFGL----ATDMSNNKTD 165 Query: 505 VAGTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQPWGGL---GPAQVVGAVAFQN 335 + GT +MAPE ++ KCDVYSFG++LWEL+T Q P+ L + Sbjct: 166 MQGTLRYMAPEAIKHLKYTAKCDVYSFGIMLWELMTRQLPYSHLENPNSQYAIMKAISSG 225 Query: 334 RRLPIP--KDTIPE-LAALVESCWADDPRQRPSFSSI 233 +LP+ + PE + L+E C +P +RPS I Sbjct: 226 EKLPMEAVRSDCPEGIKQLMECCMDINPEKRPSMKEI 262
>ACK1_MOUSE (O54967) Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1)| (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2) Length = 1055 Score = 90.9 bits (224), Expect = 3e-18 Identities = 52/155 (33%), Positives = 80/155 (51%), Gaps = 4/155 (2%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATT---FISSK 509 R A+ VA+G+ YL +H DL N+L+ VK+GDFGL R ++ + Sbjct: 231 RYAVQVAEGMAYLESKR--FIHRDLAARNLLLATRDLVKIGDFGLMRALPQNDDHYVMQE 288 Query: 508 SVAGTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNR 332 W APE L+ + D + FGV LWE+ T Q+PW GL +Q++ + + Sbjct: 289 HRKVPFAWCAPESLKTRTFSHASDTWMFGVTLWEMFTYGQEPWIGLNGSQILHKIDKEGE 348 Query: 331 RLPIPKDTIPELAALVESCWADDPRQRPSFSSIVD 227 RLP P+D ++ ++ CWA P RP+F ++ D Sbjct: 349 RLPRPEDCPQDIYNVMVQCWAHKPEDRPTFVALRD 383
>INSRR_MOUSE (Q9WTL4) Insulin receptor-related protein precursor (EC 2.7.10.1)| (IRR) (IR-related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain] Length = 1300 Score = 90.5 bits (223), Expect = 4e-18 Identities = 59/159 (37%), Positives = 85/159 (53%), Gaps = 8/159 (5%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVA 500 +MA ++A G+ YL VH DL N +V ++++VK+GDFG++R T K Sbjct: 1094 QMAGEIADGMAYLAAKK--FVHRDLAARNCMVSQDFTVKIGDFGMTRDVYETDYYRKGGK 1151 Query: 499 GT--PEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVV-----GAVA 344 G WMAPE L+ DV+SFGV+LWE++T+ +QP+ GL QV+ G V Sbjct: 1152 GLLPVRWMAPESLKDGIFTTHSDVWSFGVVLWEIVTLAEQPYQGLSNEQVLKFVMDGGVL 1211 Query: 343 FQNRRLPIPKDTIPELAALVESCWADDPRQRPSFSSIVD 227 + PI +L L+ CW PR RP+F I+D Sbjct: 1212 EELENCPI------QLQELMRLCWQHSPRLRPTFVHILD 1244
>FPS_DROME (P18106) Tyrosine-protein kinase Fps85D (EC 2.7.10.2) (dFer)| Length = 1325 Score = 90.5 bits (223), Expect = 4e-18 Identities = 52/149 (34%), Positives = 74/149 (49%), Gaps = 1/149 (0%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAG 497 M D A G+ YL N +H DL N LVD SVK+ DFG+SR + +S Sbjct: 1165 MCRDAAAGMRYLESKN--CIHRDLAARNCLVDLEHSVKISDFGMSREEEEYIVSDGMKQI 1222 Query: 496 TPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRLPI 320 +W APE L CDV+S+G+++WE+ + P+ G+ ++ + R+P Sbjct: 1223 PVKWTAPEALNFGKYTSLCDVWSYGILMWEIFSKGDTPYSGMTNSRARERID-TGYRMPT 1281 Query: 319 PKDTIPELAALVESCWADDPRQRPSFSSI 233 PK T E+ L+ CWA D RP F I Sbjct: 1282 PKSTPEEMYRLMLQCWAADAESRPHFDEI 1310
>IGF1R_XENLA (O73798) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (xIGF-1R) (xIGFR) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] Length = 1358 Score = 90.5 bits (223), Expect = 4e-18 Identities = 55/155 (35%), Positives = 86/155 (55%), Gaps = 3/155 (1%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVA 500 +MA ++A G++YL+ VH DL N +V ++++VK+GDFG++R T K Sbjct: 1110 QMAGEIADGMSYLNANK--FVHRDLAARNCMVTEDFTVKIGDFGMTRDIYETDYYRKGGK 1167 Query: 499 GT--PEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRR 329 G WM+PE L+ DV+SFGV+LWE+ T+ +QP+ G+ QV+ V + Sbjct: 1168 GLLPVRWMSPESLKDGVFTTNSDVWSFGVVLWEIATLAEQPYQGMSNEQVLRFV-MEGGL 1226 Query: 328 LPIPKDTIPELAALVESCWADDPRQRPSFSSIVDT 224 L P + L L+ CW +P+ RPSF I+ + Sbjct: 1227 LEKPDNCPDMLFELMRMCWQFNPKMRPSFLEIISS 1261
>WNK4_HUMAN (Q96J92) Serine/threonine-protein kinase WNK4 (EC 2.7.11.1)| (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4) Length = 1243 Score = 90.1 bits (222), Expect = 5e-18 Identities = 53/145 (36%), Positives = 80/145 (55%), Gaps = 2/145 (1%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLV-DKNWSVKVGDFGLSRFKATTFISSKSV 503 R + + +G+++LH PPI+H DLK N+ + SVK+GD GL+ K +F +KSV Sbjct: 279 RWSRQILRGLHFLHSRVPPILHRDLKCDNVFITGPTGSVKIGDLGLATLKRASF--AKSV 336 Query: 502 AGTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQPWGGL-GPAQVVGAVAFQNRRL 326 GTPE+MAPE E +E DVY+FG+ + E+ T + P+ AQ+ V + Sbjct: 337 IGTPEFMAPEMYE-EKYDEAVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTSGRKPN 395 Query: 325 PIPKDTIPELAALVESCWADDPRQR 251 K IPE+ ++E C D +R Sbjct: 396 SFHKVKIPEVKEIIEGCIRTDKNER 420
>WNK3_HUMAN (Q9BYP7) Serine/threonine-protein kinase WNK3 (EC 2.7.11.1)| (Protein kinase with no lysine 3) (Protein kinase, lysine-deficient 3) Length = 1743 Score = 90.1 bits (222), Expect = 5e-18 Identities = 53/148 (35%), Positives = 81/148 (54%), Gaps = 2/148 (1%) Frame = -1 Query: 664 VAKGINYLHCXNPPIVHWDLKTPNMLV-DKNWSVKVGDFGLSRFKATTFISSKSVAGTPE 488 + KG+ +LH PPI+H DLK N+ + SVK+GD GL+ T+F +KSV GTPE Sbjct: 257 ILKGLQFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLMRTSF--AKSVIGTPE 314 Query: 487 WMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQPWGGL-GPAQVVGAVAFQNRRLPIPKD 311 +MAPE E +E DVY+FG+ + E+ T + P+ AQ+ V + K Sbjct: 315 FMAPEMYE-EHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTSGIKPASFNKV 373 Query: 310 TIPELAALVESCWADDPRQRPSFSSIVD 227 T PE+ ++E C + +R S +++ Sbjct: 374 TDPEVKEIIEGCIRQNKSERLSIRDLLN 401
>RIPK3_RAT (Q9Z2P5) Receptor-interacting serine/threonine-protein kinase 3 (EC| 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) (Homocysteine respondent protein HCYP2) Length = 478 Score = 90.1 bits (222), Expect = 5e-18 Identities = 56/159 (35%), Positives = 86/159 (54%), Gaps = 13/159 (8%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRF----KATTFISS 512 R+ +V G+ YLH NP ++H DLK N+L+D K+ DFGLS F ++ + S Sbjct: 120 RLLEEVVLGMCYLHSLNPSLLHRDLKPSNVLLDLELHAKLADFGLSTFQGGSQSGSGSGS 179 Query: 511 KSVAGTPEWMAPEFLRGEPSNEKC-DVYSFGVILWELLTMQQPWGGLGPAQVVGAVAFQN 335 + GT ++APE L + K DVYSFGV++W +L ++ + + GAV + Sbjct: 180 RDSGGTLAYLAPELLDNDGKASKASDVYSFGVLVWTVLAGREAEVVDKTSLIRGAVCNRQ 239 Query: 334 RRLP---IPKDT-----IPELAALVESCWADDPRQRPSF 242 RR P +P D+ + L L+ CW+ +P+ RPSF Sbjct: 240 RRPPLTELPPDSPETPGLEGLKELMTHCWSSEPKDRPSF 278
>EPHB3_HUMAN (P54753) Ephrin type-B receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor HEK-2) Length = 998 Score = 89.7 bits (221), Expect = 7e-18 Identities = 58/157 (36%), Positives = 80/157 (50%), Gaps = 6/157 (3%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRF-----KATTFISS 512 M +A G+ YL N VH DL N+LV+ N KV DFGLSRF T+ SS Sbjct: 738 MLRGIAAGMKYLSEMN--YVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPTYTSS 795 Query: 511 KSVAGTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQN 335 W APE + DV+S+G+++WE+++ ++P+ + V+ AV Q+ Sbjct: 796 LGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAVE-QD 854 Query: 334 RRLPIPKDTIPELAALVESCWADDPRQRPSFSSIVDT 224 RLP P D L L+ CW D RP FS IV+T Sbjct: 855 YRLPPPMDCPTALHQLMLDCWVRDRNLRPKFSQIVNT 891
>EPHB3_MOUSE (P54754) Ephrin type-B receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4) Length = 993 Score = 89.7 bits (221), Expect = 7e-18 Identities = 58/157 (36%), Positives = 80/157 (50%), Gaps = 6/157 (3%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRF-----KATTFISS 512 M +A G+ YL N VH DL N+LV+ N KV DFGLSRF T+ SS Sbjct: 733 MLRGIAAGMKYLSEMN--YVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPTYTSS 790 Query: 511 KSVAGTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQN 335 W APE + DV+S+G+++WE+++ ++P+ + V+ AV Q+ Sbjct: 791 LGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAVE-QD 849 Query: 334 RRLPIPKDTIPELAALVESCWADDPRQRPSFSSIVDT 224 RLP P D L L+ CW D RP FS IV+T Sbjct: 850 YRLPPPMDCPTALHQLMLDCWVRDRNLRPKFSQIVNT 886
>EPB1B_XENLA (Q91736) Ephrin type-B receptor 1-B (EC 2.7.10.1) (Tyrosine-protein| kinase receptor XELK) (Fragment) Length = 902 Score = 89.7 bits (221), Expect = 7e-18 Identities = 56/157 (35%), Positives = 80/157 (50%), Gaps = 6/157 (3%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRF-----KATTFISS 512 M +A G+ YL N VH DL N+LV+ N KV DFGLSR+ T+ SS Sbjct: 642 MLRGIAAGMKYLSEMN--YVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSS 699 Query: 511 KSVAGTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQN 335 W APE +R DV+S+G+++WE+++ ++P+ + V+ A+ Q+ Sbjct: 700 LGGKIPVRWTAPEAIRYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAIE-QD 758 Query: 334 RRLPIPKDTIPELAALVESCWADDPRQRPSFSSIVDT 224 RLP P D L L+ CW D RP F IV+T Sbjct: 759 YRLPPPMDCPAALHQLMLDCWQKDRNSRPRFGEIVNT 795
>FAK1_HUMAN (Q05397) Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK)| (Protein-tyrosine kinase 2) Length = 1052 Score = 89.4 bits (220), Expect = 9e-18 Identities = 50/131 (38%), Positives = 72/131 (54%), Gaps = 2/131 (1%) Frame = -1 Query: 619 VHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAGTP-EWMAPEFLRGEPSNEK 443 VH D+ N+LV N VK+GDFGLSR+ + S P +WMAPE + Sbjct: 543 VHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSA 602 Query: 442 CDVYSFGVILWELLTMQ-QPWGGLGPAQVVGAVAFQNRRLPIPKDTIPELAALVESCWAD 266 DV+ FGV +WE+L +P+ G+ V+G + RLP+P + P L +L+ CWA Sbjct: 603 SDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIE-NGERLPMPPNCPPTLYSLMTKCWAY 661 Query: 265 DPRQRPSFSSI 233 DP +RP F+ + Sbjct: 662 DPSRRPRFTEL 672
>IGF1R_BOVIN (Q05688) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] (F Length = 640 Score = 89.4 bits (220), Expect = 9e-18 Identities = 56/155 (36%), Positives = 85/155 (54%), Gaps = 3/155 (1%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVA 500 +MA ++A G+ YL+ VH DL N +V ++++VK+GDFG++R T K Sbjct: 387 QMAGEIADGMAYLNANK--FVHRDLAARNCMVAEDFTVKIGDFGMTRDIYETDYYRKGGK 444 Query: 499 GT--PEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRR 329 G WM+PE L+ DV+SFGV+LWE+ T+ +QP+ GL QV+ V + Sbjct: 445 GLLPVRWMSPESLKDGVFTTHSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFV-MEGGL 503 Query: 328 LPIPKDTIPELAALVESCWADDPRQRPSFSSIVDT 224 L P + L L+ CW +P+ RPSF I+ + Sbjct: 504 LDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISS 538
>FAK1_RAT (O35346) Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK)| Length = 1055 Score = 89.4 bits (220), Expect = 9e-18 Identities = 50/131 (38%), Positives = 72/131 (54%), Gaps = 2/131 (1%) Frame = -1 Query: 619 VHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAGTP-EWMAPEFLRGEPSNEK 443 VH D+ N+LV N VK+GDFGLSR+ + S P +WMAPE + Sbjct: 543 VHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSA 602 Query: 442 CDVYSFGVILWELLTMQ-QPWGGLGPAQVVGAVAFQNRRLPIPKDTIPELAALVESCWAD 266 DV+ FGV +WE+L +P+ G+ V+G + RLP+P + P L +L+ CWA Sbjct: 603 SDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIE-NGERLPMPPNCPPTLYSLMTKCWAY 661 Query: 265 DPRQRPSFSSI 233 DP +RP F+ + Sbjct: 662 DPSRRPRFTEL 672
>FAK1_MOUSE (P34152) Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK)| Length = 1090 Score = 89.4 bits (220), Expect = 9e-18 Identities = 50/131 (38%), Positives = 72/131 (54%), Gaps = 2/131 (1%) Frame = -1 Query: 619 VHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAGTP-EWMAPEFLRGEPSNEK 443 VH D+ N+LV N VK+GDFGLSR+ + S P +WMAPE + Sbjct: 581 VHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSA 640 Query: 442 CDVYSFGVILWELLTMQ-QPWGGLGPAQVVGAVAFQNRRLPIPKDTIPELAALVESCWAD 266 DV+ FGV +WE+L +P+ G+ V+G + RLP+P + P L +L+ CWA Sbjct: 641 SDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIE-NGERLPMPPNCPPTLYSLMTKCWAY 699 Query: 265 DPRQRPSFSSI 233 DP +RP F+ + Sbjct: 700 DPSRRPRFTEL 710
>IGF1R_MOUSE (Q60751) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] Length = 1373 Score = 89.0 bits (219), Expect = 1e-17 Identities = 56/153 (36%), Positives = 84/153 (54%), Gaps = 3/153 (1%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVA 500 +MA ++A G+ YL+ VH DL N +V ++++VK+GDFG++R T K Sbjct: 1116 QMAGEIADGMAYLNANK--FVHRDLAARNCMVAEDFTVKIGDFGMTRDIYETDYYRKGGK 1173 Query: 499 GT--PEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRR 329 G WM+PE L+ DV+SFGV+LWE+ T+ +QP+ GL QV+ V + Sbjct: 1174 GLLPVRWMSPESLKDGVFTTHSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFV-MEGGL 1232 Query: 328 LPIPKDTIPELAALVESCWADDPRQRPSFSSIV 230 L P + L L+ CW +P+ RPSF I+ Sbjct: 1233 LDKPDNCPDMLFELMRMCWQYNPKMRPSFLEII 1265
>IGF1R_HUMAN (P08069) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 recepto Length = 1367 Score = 89.0 bits (219), Expect = 1e-17 Identities = 56/155 (36%), Positives = 85/155 (54%), Gaps = 3/155 (1%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVA 500 +MA ++A G+ YL+ VH DL N +V ++++VK+GDFG++R T K Sbjct: 1114 QMAGEIADGMAYLNANK--FVHRDLAARNCMVAEDFTVKIGDFGMTRDIYETDYYRKGGK 1171 Query: 499 GT--PEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRR 329 G WM+PE L+ DV+SFGV+LWE+ T+ +QP+ GL QV+ V + Sbjct: 1172 GLLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFV-MEGGL 1230 Query: 328 LPIPKDTIPELAALVESCWADDPRQRPSFSSIVDT 224 L P + L L+ CW +P+ RPSF I+ + Sbjct: 1231 LDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISS 1265
>SEA_AVIET (P23049) Tyrosine-protein kinase transforming protein SEA (EC| 2.7.10.2) Length = 370 Score = 89.0 bits (219), Expect = 1e-17 Identities = 60/152 (39%), Positives = 80/152 (52%), Gaps = 5/152 (3%) Frame = -1 Query: 670 LDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRF---KATTFISSKSVA 500 L VA G+ YL VH DL N ++D+ +VKV DFGL+R K I A Sbjct: 168 LQVALGMEYL--AQKKFVHRDLAARNCMLDETLTVKVADFGLARDVFGKEYYSIRQHRHA 225 Query: 499 GTP-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRL 326 P WMA E L+ + K DV+SFGV++WELLT P+ + P + + RRL Sbjct: 226 KLPVRWMALESLQTQKFTTKSDVWSFGVLMWELLTRGASPYPEVDPYD-MARYLLRGRRL 284 Query: 325 PIPKDTIPELAALVESCWADDPRQRPSFSSIV 230 P P+ L ++ SCWA P +RPSFS +V Sbjct: 285 PQPQPCPDTLYGVMLSCWAPTPEERPSFSGLV 316
>IGF1R_RAT (P24062) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] Length = 1370 Score = 89.0 bits (219), Expect = 1e-17 Identities = 56/153 (36%), Positives = 84/153 (54%), Gaps = 3/153 (1%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVA 500 +MA ++A G+ YL+ VH DL N +V ++++VK+GDFG++R T K Sbjct: 1115 QMAGEIADGMAYLNANK--FVHRDLAARNCMVAEDFTVKIGDFGMTRDIYETDYYRKGGK 1172 Query: 499 GT--PEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRR 329 G WM+PE L+ DV+SFGV+LWE+ T+ +QP+ GL QV+ V + Sbjct: 1173 GLLPVRWMSPESLKDGVFTTHSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFV-MEGGL 1231 Query: 328 LPIPKDTIPELAALVESCWADDPRQRPSFSSIV 230 L P + L L+ CW +P+ RPSF I+ Sbjct: 1232 LDKPDNCPDMLFELMRMCWQYNPKMRPSFLEII 1264
>WNK4_RAT (Q7TPK6) Serine/threonine-protein kinase WNK4 (EC 2.7.11.1)| (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4) Length = 1222 Score = 89.0 bits (219), Expect = 1e-17 Identities = 52/145 (35%), Positives = 81/145 (55%), Gaps = 2/145 (1%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLV-DKNWSVKVGDFGLSRFKATTFISSKSV 503 R + + +G+++LH PPI+H DLK N+ + + SVK+GD GL+ K +F +KSV Sbjct: 276 RWSRQILRGLHFLHSRVPPILHRDLKCDNVFITGPSGSVKIGDLGLATLKRASF--AKSV 333 Query: 502 AGTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQPWGGL-GPAQVVGAVAFQNRRL 326 GTPE+MAPE E +E DVY+FG+ + E+ T + P+ AQ+ V + Sbjct: 334 IGTPEFMAPEMYE-EKYDEAVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTSGTKPN 392 Query: 325 PIPKDTIPELAALVESCWADDPRQR 251 K +PE+ ++E C D +R Sbjct: 393 SFYKVKMPEVKEIIEGCIRTDKNER 417
>WNK4_MOUSE (Q80UE6) Serine/threonine-protein kinase WNK4 (EC 2.7.11.1)| (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4) Length = 1222 Score = 89.0 bits (219), Expect = 1e-17 Identities = 52/145 (35%), Positives = 81/145 (55%), Gaps = 2/145 (1%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLV-DKNWSVKVGDFGLSRFKATTFISSKSV 503 R + + +G+++LH PPI+H DLK N+ + + SVK+GD GL+ K +F +KSV Sbjct: 276 RWSRQILRGLHFLHSRVPPILHRDLKCDNVFITGPSGSVKIGDLGLATLKRASF--AKSV 333 Query: 502 AGTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQPWGGL-GPAQVVGAVAFQNRRL 326 GTPE+MAPE E +E DVY+FG+ + E+ T + P+ AQ+ V + Sbjct: 334 IGTPEFMAPEMYE-EKYDEAVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTSGTKPN 392 Query: 325 PIPKDTIPELAALVESCWADDPRQR 251 K +PE+ ++E C D +R Sbjct: 393 SFYKVKMPEVKEIIEGCIRTDKNER 417
>EPHB3_CHICK (Q07498) Ephrin type-B receptor 3 (EC 2.7.10.1) (Tyrosine-protein| kinase receptor CEK10) (Fragment) Length = 988 Score = 88.2 bits (217), Expect = 2e-17 Identities = 57/157 (36%), Positives = 80/157 (50%), Gaps = 6/157 (3%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKAT-----TFISS 512 M +A G+ YL N VH DL N+LV+ N KV DFGLSRF T+ SS Sbjct: 728 MLRGIAAGMKYLSEMN--YVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPADPTYTSS 785 Query: 511 KSVAGTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQN 335 W APE + DV+S+G+++WE+++ ++P+ + V+ AV Q+ Sbjct: 786 LGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAVE-QD 844 Query: 334 RRLPIPKDTIPELAALVESCWADDPRQRPSFSSIVDT 224 RLP P D L L+ CW D RP F+ IV+T Sbjct: 845 YRLPPPMDCPTALHQLMLDCWVRDRNLRPKFAQIVNT 881
>HTK7_HYDAT (Q25197) Putative insulin-like peptide receptor precursor (EC| 2.7.10.1) Length = 1477 Score = 88.2 bits (217), Expect = 2e-17 Identities = 54/153 (35%), Positives = 80/153 (52%), Gaps = 3/153 (1%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSR--FKATTFISSKS 506 +M ++A G+ YL VH DL N +V +++VK+GDFG++R ++ + Sbjct: 1154 QMVAEIADGMAYLAARK--FVHCDLAARNCMVASDFTVKIGDFGMARDIYERNYYRKDGK 1211 Query: 505 VAGTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRR 329 WMAPE L+ + DV+SFGV+LWE+ T+ QP+ G QV+ V N Sbjct: 1212 SLLPIRWMAPESLKDGIFSTASDVWSFGVVLWEICTLASQPYQGKTNEQVLNFV-LSNGH 1270 Query: 328 LPIPKDTIPELAALVESCWADDPRQRPSFSSIV 230 L P+ +L + CW DP+ RPSF IV Sbjct: 1271 LDYPEGCDYQLREFMSLCWHRDPKMRPSFLEIV 1303
>EPHB1_RAT (P09759) Ephrin type-B receptor 1 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-2) (ELK) Length = 984 Score = 88.2 bits (217), Expect = 2e-17 Identities = 55/157 (35%), Positives = 80/157 (50%), Gaps = 6/157 (3%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRF-----KATTFISS 512 M +A G+ YL N VH DL N+LV+ N KV DFGLSR+ T+ SS Sbjct: 724 MLRGIAAGMKYLSEMN--YVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSS 781 Query: 511 KSVAGTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQN 335 W APE + DV+S+G+++WE+++ ++P+ + V+ A+ Q+ Sbjct: 782 LGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIE-QD 840 Query: 334 RRLPIPKDTIPELAALVESCWADDPRQRPSFSSIVDT 224 RLP P D L L+ CW D RP F+ IV+T Sbjct: 841 YRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNT 877
>NTRK1_HUMAN (P04629) High affinity nerve growth factor receptor precursor (EC| 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1 transforming tyrosine kinase protein) (p140-TrkA) (Trk-A) Length = 796 Score = 87.8 bits (216), Expect = 3e-17 Identities = 55/151 (36%), Positives = 79/151 (52%), Gaps = 3/151 (1%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSR-FKATTFISSKSVA 500 +A VA G+ YL + VH DL T N LV + VK+GDFG+SR +T + Sbjct: 630 VASQVAAGMVYLAGLH--FVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRT 687 Query: 499 GTP-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRL 326 P WM PE + + DV+SFGV+LWE+ T +QPW L + + + Q R L Sbjct: 688 MLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCIT-QGREL 746 Query: 325 PIPKDTIPELAALVESCWADDPRQRPSFSSI 233 P+ PE+ A++ CW +P+QR S + Sbjct: 747 ERPRACPPEVYAIMRGCWQREPQQRHSIKDV 777
>EPHB1_HUMAN (P54762) Ephrin type-B receptor 1 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK) Length = 984 Score = 87.8 bits (216), Expect = 3e-17 Identities = 55/157 (35%), Positives = 80/157 (50%), Gaps = 6/157 (3%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRF-----KATTFISS 512 M +A G+ YL N VH DL N+LV+ N KV DFGLSR+ T+ SS Sbjct: 724 MLRGIAAGMKYLAEMN--YVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSS 781 Query: 511 KSVAGTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQN 335 W APE + DV+S+G+++WE+++ ++P+ + V+ A+ Q+ Sbjct: 782 LGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIE-QD 840 Query: 334 RRLPIPKDTIPELAALVESCWADDPRQRPSFSSIVDT 224 RLP P D L L+ CW D RP F+ IV+T Sbjct: 841 YRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNT 877
>FAK1_XENLA (Q91738) Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK)| Length = 1068 Score = 87.8 bits (216), Expect = 3e-17 Identities = 49/131 (37%), Positives = 72/131 (54%), Gaps = 2/131 (1%) Frame = -1 Query: 619 VHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAGTP-EWMAPEFLRGEPSNEK 443 VH D+ N+LV + VK+GDFGLSR+ + S P +WMAPE + Sbjct: 556 VHRDIAARNVLVSSSDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSA 615 Query: 442 CDVYSFGVILWELLTMQ-QPWGGLGPAQVVGAVAFQNRRLPIPKDTIPELAALVESCWAD 266 DV+ FGV +WE+L +P+ G+ V+G + RLP+P + P L +L+ CWA Sbjct: 616 SDVWMFGVCMWEILMYGVKPFQGVKNNDVIGRIE-NGERLPMPPNCPPTLYSLMTKCWAY 674 Query: 265 DPRQRPSFSSI 233 DP +RP F+ + Sbjct: 675 DPSRRPRFTEL 685
>RON_HUMAN (Q04912) Macrophage-stimulating protein receptor precursor (EC| 2.7.10.1) (MSP receptor) (p185-Ron) (CDw136 antigen) [Contains: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain] Length = 1400 Score = 87.4 bits (215), Expect = 4e-17 Identities = 58/152 (38%), Positives = 83/152 (54%), Gaps = 5/152 (3%) Frame = -1 Query: 670 LDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRF---KATTFISSKSVA 500 L VA+G+ YL VH DL N ++D++++VKV DFGL+R + + A Sbjct: 1190 LQVARGMEYL--AEQKFVHRDLAARNCMLDESFTVKVADFGLARDILDREYYSVQQHRHA 1247 Query: 499 GTP-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRL 326 P +WMA E L+ K DV+SFGV+LWELLT P+ + P + +A Q RRL Sbjct: 1248 RLPVKWMALESLQTYRFTTKSDVWSFGVLLWELLTRGAPPYRHIDPFDLTHFLA-QGRRL 1306 Query: 325 PIPKDTIPELAALVESCWADDPRQRPSFSSIV 230 P P+ L +++ CW DP RP+F +V Sbjct: 1307 PQPEYCPDSLYQVMQQCWEADPAVRPTFRVLV 1338
>EPHB2_MOUSE (P54763) Ephrin type-B receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3) Length = 994 Score = 87.4 bits (215), Expect = 4e-17 Identities = 55/157 (35%), Positives = 80/157 (50%), Gaps = 6/157 (3%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRF-----KATTFISS 512 M +A G+ YL N VH DL N+LV+ N KV DFGLSRF T+ S+ Sbjct: 734 MLRGIAAGMKYLADMN--YVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSA 791 Query: 511 KSVAGTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQN 335 W APE ++ DV+S+G+++WE+++ ++P+ + V+ A+ Q+ Sbjct: 792 LGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIE-QD 850 Query: 334 RRLPIPKDTIPELAALVESCWADDPRQRPSFSSIVDT 224 RLP P D L L+ CW D RP F IV+T Sbjct: 851 YRLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNT 887
>EPHB2_HUMAN (P29323) Ephrin type-B receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen) Length = 1055 Score = 87.4 bits (215), Expect = 4e-17 Identities = 55/157 (35%), Positives = 80/157 (50%), Gaps = 6/157 (3%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRF-----KATTFISS 512 M +A G+ YL N VH DL N+LV+ N KV DFGLSRF T+ S+ Sbjct: 726 MLRGIAAGMKYLADMN--YVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSA 783 Query: 511 KSVAGTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQN 335 W APE ++ DV+S+G+++WE+++ ++P+ + V+ A+ Q+ Sbjct: 784 LGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIE-QD 842 Query: 334 RRLPIPKDTIPELAALVESCWADDPRQRPSFSSIVDT 224 RLP P D L L+ CW D RP F IV+T Sbjct: 843 YRLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNT 879
>INSR_HUMAN (P06213) Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220| antigen) [Contains: Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1382 Score = 87.0 bits (214), Expect = 5e-17 Identities = 54/154 (35%), Positives = 83/154 (53%), Gaps = 3/154 (1%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVA 500 +MA ++A G+ YL+ VH DL N +V +++VK+GDFG++R T K Sbjct: 1138 QMAAEIADGMAYLNAKK--FVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGK 1195 Query: 499 GT--PEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRR 329 G WMAPE L+ D++SFGV+LWE+ ++ +QP+ GL QV+ V Sbjct: 1196 GLLPVRWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFV-MDGGY 1254 Query: 328 LPIPKDTIPELAALVESCWADDPRQRPSFSSIVD 227 L P + + L+ CW +P+ RP+F IV+ Sbjct: 1255 LDQPDNCPERVTDLMRMCWQFNPKMRPTFLEIVN 1288
>EPHB2_CHICK (P28693) Ephrin type-B receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor CEK5) Length = 1004 Score = 87.0 bits (214), Expect = 5e-17 Identities = 55/157 (35%), Positives = 80/157 (50%), Gaps = 6/157 (3%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRF-----KATTFISS 512 M +A G+ YL N VH DL N+LV+ N KV DFGLSRF T+ S+ Sbjct: 744 MLRGIAAGMKYLADMN--YVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSA 801 Query: 511 KSVAGTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQN 335 W APE ++ DV+S+G+++WE+++ ++P+ + V+ A+ Q+ Sbjct: 802 LGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIE-QD 860 Query: 334 RRLPIPKDTIPELAALVESCWADDPRQRPSFSSIVDT 224 RLP P D L L+ CW D RP F IV+T Sbjct: 861 YRLPPPMDCPNALHQLMLDCWQKDRNHRPKFGQIVNT 897
>NTRK1_RAT (P35739) High affinity nerve growth factor receptor precursor (EC| 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (p140-TrkA) (Slow nerve growth factor receptor) (Trk-A) Length = 799 Score = 87.0 bits (214), Expect = 5e-17 Identities = 54/151 (35%), Positives = 80/151 (52%), Gaps = 3/151 (1%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSR-FKATTFISSKSVA 500 +A VA G+ YL + VH DL T N LV + VK+GDFG+SR +T + Sbjct: 633 VASQVAAGMVYLASLH--FVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRT 690 Query: 499 GTP-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRL 326 P WM PE + + + DV+SFGV+LWE+ T +QPW L + + + Q R L Sbjct: 691 MLPIRWMPPESILYRKFSTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIECIT-QGREL 749 Query: 325 PIPKDTIPELAALVESCWADDPRQRPSFSSI 233 P+ P++ A++ CW +P+QR S + Sbjct: 750 ERPRACPPDVYAIMRGCWQREPQQRLSMKDV 780
>FAK1_CHICK (Q00944) Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK)| Length = 1053 Score = 87.0 bits (214), Expect = 5e-17 Identities = 54/159 (33%), Positives = 82/159 (51%), Gaps = 10/159 (6%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPI--------VHWDLKTPNMLVDKNWSVKVGDFGLSRFKATT 524 + +LD+A I Y + + + VH D+ N+LV VK+GDFGLSR+ + Sbjct: 515 KFSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSATDCVKLGDFGLSRYMEDS 574 Query: 523 FISSKSVAGTP-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQ-QPWGGLGPAQVVGA 350 S P +WMAPE + DV+ FGV +WE+L +P+ G+ V+G Sbjct: 575 TYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGR 634 Query: 349 VAFQNRRLPIPKDTIPELAALVESCWADDPRQRPSFSSI 233 + RLP+P + P L +L+ CWA DP +RP F+ + Sbjct: 635 IE-NGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTEL 672
>CAD96_DROME (Q9VBW3) Tyrosine kinase receptor Cad96Ca precursor (EC 2.7.10.1)| (Cadherin 96Ca) (Tyrosine kinase receptor HD-14) Length = 773 Score = 86.7 bits (213), Expect = 6e-17 Identities = 52/148 (35%), Positives = 83/148 (56%), Gaps = 3/148 (2%) Frame = -1 Query: 664 VAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAGTP-- 491 VAKG++YL + I+H DL N+L+ + + KV DFG +R T+ I + G Sbjct: 594 VAKGMDYL--TSRGIIHRDLAARNILITDDHTCKVADFGFARDVITSKIYERKSEGKLPI 651 Query: 490 EWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRLPIPK 314 WMA E L + K D++SFG+++WE++T+ P+ G+ A V+ V RL P+ Sbjct: 652 RWMATESLYDNIFSVKSDIWSFGILMWEIVTLGSTPYPGISAADVMRKVR-DGYRLEKPE 710 Query: 313 DTIPELAALVESCWADDPRQRPSFSSIV 230 EL ++ CW+ DP++RP F+ I+ Sbjct: 711 HCRRELYNIMYYCWSHDPQERPLFAEII 738
>SRMS_HUMAN (Q9H3Y6) Tyrosine-protein kinase Srms (EC 2.7.10.2)| Length = 488 Score = 86.7 bits (213), Expect = 6e-17 Identities = 54/149 (36%), Positives = 80/149 (53%), Gaps = 2/149 (1%) Frame = -1 Query: 673 ALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAGT 494 A VA+G++YL +VH DL N+LVD + KV DFGL+R S S + Sbjct: 331 ACQVAEGMSYLE--EQRVVHRDLAARNVLVDDGLACKVADFGLARLLKDDIYSPSSSSKI 388 Query: 493 P-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQ-PWGGLGPAQVVGAVAFQNRRLPI 320 P +W APE ++K DV+SFGV+L E+ T Q P+ G+ + + + + RLP Sbjct: 389 PVKWTAPEAANYRVFSQKSDVWSFGVLLHEVFTYGQCPYEGMTNHETLQQI-MRGYRLPR 447 Query: 319 PKDTIPELAALVESCWADDPRQRPSFSSI 233 P E+ L+ CW P +RPSF+++ Sbjct: 448 PAACPAEVYVLMLECWRSSPEERPSFATL 476
>EPHB3_BRARE (O13147) Ephrin type-B receptor 3 (EC 2.7.10.1) (Tyrosine-protein| kinase receptor ZEK3) (EPH-like kinase 3) (Fragment) Length = 500 Score = 86.7 bits (213), Expect = 6e-17 Identities = 56/157 (35%), Positives = 78/157 (49%), Gaps = 6/157 (3%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRF-----KATTFISS 512 M +A G+ YL N VH DL N+LV+ N KV DFGLSRF T+ SS Sbjct: 292 MLRGIAAGMKYLSDMN--YVHRDLAARNVLVNSNLVCKVSDFGLSRFLDDNSSDPTYTSS 349 Query: 511 KSVAGTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQN 335 W APE + DV+S+G+++WE+++ ++P+ + V+ AV Q+ Sbjct: 350 LGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVMNAVE-QD 408 Query: 334 RRLPIPKDTIPELAALVESCWADDPRQRPSFSSIVDT 224 RLP P D L L+ CW + RP F IV T Sbjct: 409 YRLPPPMDCPAVLHQLMLECWVKERNMRPRFGQIVST 445
>SRK4_SPOLA (P42690) Tyrosine-protein kinase isoform SRK4 (EC 2.7.10.2)| Length = 506 Score = 86.7 bits (213), Expect = 6e-17 Identities = 54/150 (36%), Positives = 83/150 (55%), Gaps = 2/150 (1%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAG 497 M VA G++YL N +H DL N+LV ++ KV DFGL+R +K A Sbjct: 339 MCSQVASGMSYLEQQN--YIHRDLAARNILVGEHKICKVADFGLARVIDEEIYEAKLGAK 396 Query: 496 TP-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQ-PWGGLGPAQVVGAVAFQNRRLP 323 P +W APE K DV+SFG++L+E++T + P+ G+ AQV+ + Q+ R+P Sbjct: 397 FPIKWTAPEAAMYSRFTIKSDVWSFGIVLYEVITYGRFPYPGMTNAQVLEQIQ-QSYRMP 455 Query: 322 IPKDTIPELAALVESCWADDPRQRPSFSSI 233 P +L A++ CW +DP RP+F ++ Sbjct: 456 RPMGCPEKLYAIMMDCWREDPASRPTFETL 485
>INSR_MOUSE (P15208) Insulin receptor precursor (EC 2.7.10.1) (IR) [Contains:| Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1372 Score = 86.3 bits (212), Expect = 8e-17 Identities = 55/155 (35%), Positives = 84/155 (54%), Gaps = 4/155 (2%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVA 500 +M ++A G+ YL+ VH DL N +V +++VK+GDFG++R T K Sbjct: 1128 QMTAEIADGMAYLNAKK--FVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGK 1185 Query: 499 GT--PEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRR 329 G WM+PE L+ D++SFGV+LWE+ ++ +QP+ GL QV+ V + Sbjct: 1186 GLLPVRWMSPESLKDGVFTASSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFV--MDGG 1243 Query: 328 LPIPKDTIPE-LAALVESCWADDPRQRPSFSSIVD 227 P D PE L L+ CW +P+ RP+F IV+ Sbjct: 1244 YLDPPDNCPERLTDLMRMCWQFNPKMRPTFLEIVN 1278
>INSR_RAT (P15127) Insulin receptor precursor (EC 2.7.10.1) (IR) [Contains:| Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1383 Score = 86.3 bits (212), Expect = 8e-17 Identities = 55/155 (35%), Positives = 84/155 (54%), Gaps = 4/155 (2%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVA 500 +M ++A G+ YL+ VH DL N +V +++VK+GDFG++R T K Sbjct: 1139 QMTAEIADGMAYLNAKK--FVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGK 1196 Query: 499 GT--PEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRR 329 G WM+PE L+ D++SFGV+LWE+ ++ +QP+ GL QV+ V + Sbjct: 1197 GLLPVRWMSPESLKDGVFTASSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFV--MDGG 1254 Query: 328 LPIPKDTIPE-LAALVESCWADDPRQRPSFSSIVD 227 P D PE L L+ CW +P+ RP+F IV+ Sbjct: 1255 YLDPPDNCPERLTDLMRMCWQFNPKMRPTFLEIVN 1289
>EPHB2_COTJA (Q90344) Ephrin type-B receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor QEK5) Length = 987 Score = 86.3 bits (212), Expect = 8e-17 Identities = 55/157 (35%), Positives = 79/157 (50%), Gaps = 6/157 (3%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRF-----KATTFISS 512 M +A G+ YL N VH DL N LV+ N KV DFGLSRF T+ S+ Sbjct: 727 MLRGIAAGMKYLADMN--YVHRDLAARNTLVNSNLVCKVSDFGLSRFLEDDTSDPTYTSA 784 Query: 511 KSVAGTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQN 335 W APE ++ DV+S+G+++WE+++ ++P+ + V+ A+ Q+ Sbjct: 785 LGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIE-QD 843 Query: 334 RRLPIPKDTIPELAALVESCWADDPRQRPSFSSIVDT 224 RLP P D L L+ CW D RP F IV+T Sbjct: 844 YRLPPPMDCPNALHQLMLDCWQKDRNHRPKFGQIVNT 880
>MET_OTOGA (Q2QLH6) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1382 Score = 86.3 bits (212), Expect = 8e-17 Identities = 58/151 (38%), Positives = 80/151 (52%), Gaps = 4/151 (2%) Frame = -1 Query: 670 LDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRF---KATTFISSKSVA 500 L VAKG+ YL + VH DL N ++D+N++VKV DFGL+R K + +K+ A Sbjct: 1187 LQVAKGMKYL--ASKKFVHRDLAARNCMLDENFTVKVADFGLARDMYDKEYYSVHNKTGA 1244 Query: 499 GTP-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQPWGGLGPAQVVGAVAFQNRRLP 323 P +WMA E L+ + K DV+SFGV+LWEL+T P + Q RRL Sbjct: 1245 KLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLL 1304 Query: 322 IPKDTIPELAALVESCWADDPRQRPSFSSIV 230 P+ L ++ CW RPSFS +V Sbjct: 1305 QPEYCPDPLYEVMLKCWHPKAEMRPSFSELV 1335
>FGFR4_HUMAN (P22455) Fibroblast growth factor receptor 4 precursor (EC 2.7.10.1)| (FGFR-4) (CD334 antigen) Length = 802 Score = 85.9 bits (211), Expect = 1e-16 Identities = 52/152 (34%), Positives = 81/152 (53%), Gaps = 3/152 (1%) Frame = -1 Query: 673 ALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAGT 494 A VA+G+ YL +H DL N+LV ++ +K+ DFGL+R K+ G Sbjct: 593 AYQVARGMQYLESRK--CIHRDLAARNVLVTEDNVMKIADFGLARGVHHIDYYKKTSNGR 650 Query: 493 --PEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRLP 323 +WMAPE L + DV+SFG++LWE+ T+ P+ G+ P + + ++ + R+ Sbjct: 651 LPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGI-PVEELFSLLREGHRMD 709 Query: 322 IPKDTIPELAALVESCWADDPRQRPSFSSIVD 227 P PEL L+ CW P QRP+F +V+ Sbjct: 710 RPPHCPPELYGLMRECWHAAPSQRPTFKQLVE 741
>VGFR2_MOUSE (P35918) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Protein-tyrosine kinase receptor flk-1) (Fetal liver kinase 1) (Kinase NYK) Length = 1367 Score = 85.9 bits (211), Expect = 1e-16 Identities = 50/152 (32%), Positives = 81/152 (53%), Gaps = 3/152 (1%) Frame = -1 Query: 673 ALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSR--FKATTFISSKSVA 500 + VAKG+ +L + +H DL N+L+ + VK+ DFGL+R +K ++ Sbjct: 1007 SFQVAKGMEFL--ASRKCIHRDLAARNILLSEKNVVKICDFGLARDIYKDPDYVRKGDAR 1064 Query: 499 GTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRLP 323 +WMAPE + + DV+SFGV+LWE+ ++ P+ G+ + + R+ Sbjct: 1065 LPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMR 1124 Query: 322 IPKDTIPELAALVESCWADDPRQRPSFSSIVD 227 P T PE+ + CW +DP QRPSFS +V+ Sbjct: 1125 APDYTTPEMYQTMLDCWHEDPNQRPSFSELVE 1156
>KIN15_CAEEL (P34891) Receptor-like tyrosine-protein kinase kin-15 precursor (EC| 2.7.10.1) Length = 488 Score = 85.9 bits (211), Expect = 1e-16 Identities = 52/151 (34%), Positives = 86/151 (56%), Gaps = 5/151 (3%) Frame = -1 Query: 664 VAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSR-FKATTFISSKSVAGTP- 491 +A+G+ YL + P VH DL N+L++KN ++++ DFGL+R ++ + GTP Sbjct: 303 IAEGMEYL--ASIPCVHRDLALRNVLLNKNKTIRIADFGLARKYQVDGYYRITKGVGTPM 360 Query: 490 --EWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRLPI 320 WMAPE +R EK DV+S+GV L+E+ ++ + P+ + + V V Q +LP+ Sbjct: 361 PARWMAPEVMREGKCTEKSDVWSYGVSLYEMFSLGELPYSNVSNSDVFEHVV-QGNQLPM 419 Query: 319 PKDTIPELAALVESCWADDPRQRPSFSSIVD 227 P+ P++ ++ W D RPSFS V+ Sbjct: 420 PQYCHPKMYDRMKQFWNFDATFRPSFSKCVE 450
>KIN16_CAEEL (P34892) Receptor-like tyrosine-protein kinase kin-16 precursor (EC| 2.7.10.1) Length = 495 Score = 85.9 bits (211), Expect = 1e-16 Identities = 54/153 (35%), Positives = 87/153 (56%), Gaps = 5/153 (3%) Frame = -1 Query: 670 LDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRF--KATTFISSKSV-A 500 L +A G+ YL + P+VH DL N+L+ KN ++++ DFG++R + +I K+ A Sbjct: 303 LQIANGMQYL--ASIPMVHRDLALRNVLLKKNKTIRIADFGMARTHENKSYYIPQKTKDA 360 Query: 499 GTP-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRL 326 P WM+PE EK DV+SFG+ L+E+ T+ Q P+ + P++ + RR Sbjct: 361 PVPVRWMSPEAFDTMKFTEKSDVWSFGICLYEIFTLGQLPYPDV-PSERIYEYMHSGRRC 419 Query: 325 PIPKDTIPELAALVESCWADDPRQRPSFSSIVD 227 P P+ EL L++ CW + P RP+FS+ V+ Sbjct: 420 PQPQHCHVELYDLMKLCWHEKPELRPNFSNCVE 452
>EPHB3_XENLA (Q91735) Ephrin type-B receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor TCK) Length = 974 Score = 85.9 bits (211), Expect = 1e-16 Identities = 54/153 (35%), Positives = 78/153 (50%), Gaps = 6/153 (3%) Frame = -1 Query: 664 VAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRF-----KATTFISSKSVA 500 +A G+ YL N VH DL N+LV+ N KV DFGLSRF T+ S+ Sbjct: 718 IASGMKYLSEMN--YVHRDLAARNILVNSNLVCKVSDFGLSRFLENSRSDPTYTSALGGK 775 Query: 499 GTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRLP 323 W APE + DV+S+G+++WE+++ ++P+ + V+ A+ Q+ RLP Sbjct: 776 IPIRWTAPEAISYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAIE-QDYRLP 834 Query: 322 IPKDTIPELAALVESCWADDPRQRPSFSSIVDT 224 P D L L+ CW D RP FS IV + Sbjct: 835 PPMDCPSALHQLMLDCWLRDRNLRPKFSQIVSS 867
>RLK5_ARATH (P47735) Receptor-like protein kinase 5 precursor (EC 2.7.11.1)| Length = 999 Score = 85.5 bits (210), Expect = 1e-16 Identities = 46/104 (44%), Positives = 71/104 (68%), Gaps = 6/104 (5%) Frame = -1 Query: 679 RMALDVAKGINYLH--CXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFK----ATTFI 518 R+ALD A+G++YLH C PPIVH D+K+ N+L+D ++ KV DFG+++ + T Sbjct: 795 RIALDAAEGLSYLHHDCV-PPIVHRDVKSSNILLDSDYGAKVADFGIAKVGQMSGSKTPE 853 Query: 517 SSKSVAGTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQP 386 + +AG+ ++APE++ NEK D+YSFGV+L EL+T +QP Sbjct: 854 AMSGIAGSCGYIAPEYVYTLRVNEKSDIYSFGVVLLELVTGKQP 897
>EPHB5_CHICK (Q07497) Ephrin type-B receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase CEK9) Length = 1002 Score = 85.5 bits (210), Expect = 1e-16 Identities = 54/155 (34%), Positives = 78/155 (50%), Gaps = 6/155 (3%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRF-----KATTFISS 512 M +A G+ YL N VH DL N+LV+ N KV DFGLSRF T+ + Sbjct: 742 MLRGIAAGMRYLSDMN--YVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDASNPTYTGA 799 Query: 511 KSVAGTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQN 335 W APE ++ DV+S+G+++WE+++ ++P+ + V+ A+ Q+ Sbjct: 800 LGCKIPIRWTAPEAVQYRKFTSSSDVWSYGIVMWEVMSYGERPYWDMSNQDVINAID-QD 858 Query: 334 RRLPIPKDTIPELAALVESCWADDPRQRPSFSSIV 230 RLP P D L L+ CW D QRP F IV Sbjct: 859 YRLPPPPDCPTVLHLLMLDCWQKDRVQRPKFEQIV 893
>SRC_RSVSE (P63185) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 85.5 bits (210), Expect = 1e-16 Identities = 54/147 (36%), Positives = 79/147 (53%), Gaps = 2/147 (1%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAG 497 MA +A G+ Y+ N VH DL+ N+LV +N KV DFGL+R +++ A Sbjct: 365 MAAQIASGMAYVERMN--YVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAK 422 Query: 496 TP-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRLP 323 P +W APE K DV+SFG++L EL T + P+ G+G +V+ V + R+P Sbjct: 423 FPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMGNGEVLDRVE-RGYRMP 481 Query: 322 IPKDTIPELAALVESCWADDPRQRPSF 242 P + L L+ CW DP +RP+F Sbjct: 482 CPPECPESLHDLMSQCWRRDPEERPTF 508
>TIE1_BRARE (O73792) Tyrosine-protein kinase receptor Tie-1 (EC 2.7.10.1)| (Fragment) Length = 184 Score = 85.5 bits (210), Expect = 1e-16 Identities = 55/151 (36%), Positives = 82/151 (54%), Gaps = 2/151 (1%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVA 500 + A DVA G++YL + +H DL N+LV N K+ DFGLSR + K++ Sbjct: 4 QFAADVATGMHYL--SDKQFIHRDLAARNVLVGDNLVAKIADFGLSRGEEVYV--KKTMG 59 Query: 499 GTP-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRL 326 P WMA E L K DV+SFGV+LWE++++ P+ G+ A++ + Q R+ Sbjct: 60 RLPVRWMAIESLNYSVYTTKSDVWSFGVLLWEIVSLGGTPYCGMTCAELYEKLP-QGYRM 118 Query: 325 PIPKDTIPELAALVESCWADDPRQRPSFSSI 233 P++ E+ L+ CW D P +RP FS I Sbjct: 119 EQPRNCDDEVYELMRQCWRDRPYERPPFSQI 149
>PTK6_MOUSE (Q64434) Tyrosine-protein kinase 6 (EC 2.7.10.2) (SRC-related| intestinal kinase) Length = 451 Score = 85.5 bits (210), Expect = 1e-16 Identities = 55/150 (36%), Positives = 78/150 (52%), Gaps = 1/150 (0%) Frame = -1 Query: 673 ALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAGT 494 A VA+G+ YL N +H DL N+LV +N KVGDFGL+R S Sbjct: 293 ASQVAEGMCYLESQN--YIHRDLAARNVLVTENNLCKVGDFGLARLVKEDIYLSHEHNVP 350 Query: 493 PEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRLPIP 317 +W APE L + K DV+SFGV+L E+ + Q P+ G+ + V R+P P Sbjct: 351 YKWTAPEALSRGHYSIKSDVWSFGVLLHEIFSRGQMPYPGMSNHETFLRVD-AGYRMPCP 409 Query: 316 KDTIPELAALVESCWADDPRQRPSFSSIVD 227 + P + L+ SCW+ DP+QRP F + + Sbjct: 410 LECPPNIHKLMLSCWSRDPKQRPCFKDLCE 439
>ABL2_HUMAN (P42684) Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine| leukemia viral oncogene homolog 2) (Tyrosine kinase ARG) Length = 1182 Score = 85.1 bits (209), Expect = 2e-16 Identities = 53/148 (35%), Positives = 79/148 (53%), Gaps = 2/148 (1%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAG 497 MA ++ + YL N +H DL N LV +N VKV DFGLSR ++ + A Sbjct: 389 MATQISSAMEYLEKKN--FIHRDLAARNCLVGENHVVKVADFGLSRLMTGDTYTAHAGAK 446 Query: 496 TP-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRLP 323 P +W APE L + K DV++FGV+LWE+ T P+ G+ +QV + + R+ Sbjct: 447 FPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLE-KGYRME 505 Query: 322 IPKDTIPELAALVESCWADDPRQRPSFS 239 P+ P++ L+ +CW P RPSF+ Sbjct: 506 QPEGCPPKVYELMRACWKWSPADRPSFA 533
>VGFR3_RAT (Q91ZT1) Vascular endothelial growth factor receptor 3 precursor (EC| 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4) Length = 1363 Score = 85.1 bits (209), Expect = 2e-16 Identities = 47/152 (30%), Positives = 85/152 (55%), Gaps = 3/152 (1%) Frame = -1 Query: 673 ALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSR--FKATTFISSKSVA 500 + VA+G+ +L + +H DL N+L+ ++ VK+ DFGL+R +K ++ S Sbjct: 1018 SFQVARGMEFL--ASRKCIHRDLAARNILLSESDIVKICDFGLARDIYKDPDYVRKGSAR 1075 Query: 499 GTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRLP 323 +WMAPE + + + DV+SFGV+LWE+ ++ P+ G+ + R+ Sbjct: 1076 LPLKWMAPESIFDKVYTTQSDVWSFGVLLWEIFSLGASPYPGVQINEEFCQRLKDGTRMR 1135 Query: 322 IPKDTIPELAALVESCWADDPRQRPSFSSIVD 227 P+ P + +++SCW+ DP+ RP+FS +V+ Sbjct: 1136 APELATPAIRHIMQSCWSGDPKARPAFSDLVE 1167
>VGFR3_MOUSE (P35917) Vascular endothelial growth factor receptor 3 precursor (EC| 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4) Length = 1363 Score = 85.1 bits (209), Expect = 2e-16 Identities = 47/152 (30%), Positives = 85/152 (55%), Gaps = 3/152 (1%) Frame = -1 Query: 673 ALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSR--FKATTFISSKSVA 500 + VA+G+ +L + +H DL N+L+ ++ VK+ DFGL+R +K ++ S Sbjct: 1018 SFQVARGMEFL--ASRKCIHRDLAARNILLSESDIVKICDFGLARDIYKDPDYVRKGSAR 1075 Query: 499 GTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRLP 323 +WMAPE + + + DV+SFGV+LWE+ ++ P+ G+ + R+ Sbjct: 1076 LPLKWMAPESIFDKVYTTQSDVWSFGVLLWEIFSLGASPYPGVQINEEFCQRLKDGTRMR 1135 Query: 322 IPKDTIPELAALVESCWADDPRQRPSFSSIVD 227 P+ P + +++SCW+ DP+ RP+FS +V+ Sbjct: 1136 APELATPAIRHIMQSCWSGDPKARPAFSDLVE 1167
>EPHB1_CHICK (Q07494) Ephrin type-B receptor 1 (EC 2.7.10.1) (Tyrosine-protein| kinase receptor EPH-2) (Tyrosine kinase CEK6 receptor) (Fragment) Length = 984 Score = 85.1 bits (209), Expect = 2e-16 Identities = 54/157 (34%), Positives = 79/157 (50%), Gaps = 6/157 (3%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRF-----KATTFISS 512 M +A G+ YL N VH DL N+LV+ N KV DFGLSR+ T+ SS Sbjct: 724 MLRGIAAGMKYLAEMN--YVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSS 781 Query: 511 KSVAGTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQN 335 W APE + DV+S+G+++WE+++ ++P+ + V+ A+ Q+ Sbjct: 782 LGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIE-QD 840 Query: 334 RRLPIPKDTIPELAALVESCWADDPRQRPSFSSIVDT 224 RLP P D L L+ CW D RP + IV+T Sbjct: 841 YRLPPPMDCPAALHQLMLDCWQKDRNTRPRLAEIVNT 877
>FAK2_RAT (P70600) Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal| adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) Length = 1009 Score = 85.1 bits (209), Expect = 2e-16 Identities = 55/150 (36%), Positives = 77/150 (51%), Gaps = 2/150 (1%) Frame = -1 Query: 673 ALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAGT 494 AL + K + YL N VH D+ N+LV VK+GDFGLSR+ SV Sbjct: 530 ALQICKAMAYLESIN--CVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRL 587 Query: 493 P-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRLPI 320 P +WM+PE + DV+ F V +WE+L+ +QP+ L V+G + + RLP Sbjct: 588 PIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLE-KGDRLPK 646 Query: 319 PKDTIPELAALVESCWADDPRQRPSFSSIV 230 P+ P L L+ CW DP RP F+ +V Sbjct: 647 PELCPPVLYTLMTRCWDYDPSDRPRFTELV 676
>INSR_AEDAE (Q93105) Insulin-like receptor precursor (EC 2.7.10.1) (MIR)| [Contains: Insulin-like receptor alpha chain; Insulin-like receptor beta chain] Length = 1390 Score = 84.7 bits (208), Expect = 2e-16 Identities = 54/153 (35%), Positives = 79/153 (51%), Gaps = 3/153 (1%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVA 500 +MA+++A GI L VH DL N +V + +VK+GDFG++R T K Sbjct: 1141 QMAIEIADGIGVLSAKK--FVHRDLAARNCMVADDMTVKIGDFGMTRDIYETDYYRKGTK 1198 Query: 499 G--TPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRR 329 G WMAPE L+ + DV+S+GV+LWE+ T+ QP+ GL QV+ V Sbjct: 1199 GFLPVRWMAPESLKDGIFSSSSDVFSYGVVLWEMATLASQPYQGLTNDQVLRYV-IDGGV 1257 Query: 328 LPIPKDTIPELAALVESCWADDPRQRPSFSSIV 230 + P++ L L+ CW P RP+F I+ Sbjct: 1258 MERPENCPDNLYNLMRRCWQHRPTARPTFMEII 1290
>FGFR1_DROME (Q07407) Fibroblast growth factor receptor homolog 1 precursor (EC| 2.7.10.1) (Protein heartless) Length = 729 Score = 84.7 bits (208), Expect = 2e-16 Identities = 49/154 (31%), Positives = 85/154 (55%), Gaps = 3/154 (1%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVA 500 + A +A+G++YL + +H DL N+LV ++ +K+ DFGL+R +T K+ Sbjct: 535 KFAHQIARGMDYL--ASRRCIHRDLAARNVLVSDDYVLKIADFGLARDIQSTDYYRKNTN 592 Query: 499 GTP--EWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRR 329 G +WMAPE L+ + + K DV+S+G++LWE++T QQP+ + A+ + +R Sbjct: 593 GRLPIKWMAPESLQEKFYDSKSDVWSYGILLWEIMTYGQQPYPTIMSAEELYTYLMSGQR 652 Query: 328 LPIPKDTIPELAALVESCWADDPRQRPSFSSIVD 227 + P + L+ CW + RP F+ IV+ Sbjct: 653 MEKPAKCSMNIYILMRQCWHFNADDRPPFTEIVE 686
>TIE1_HUMAN (P35590) Tyrosine-protein kinase receptor Tie-1 precursor (EC| 2.7.10.1) Length = 1138 Score = 84.7 bits (208), Expect = 2e-16 Identities = 54/151 (35%), Positives = 81/151 (53%), Gaps = 2/151 (1%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVA 500 R A D A G+ YL +H DL N+LV +N + K+ DFGLSR + K++ Sbjct: 958 RFASDAANGMQYL--SEKQFIHRDLAARNVLVGENLASKIADFGLSRGEEVYV--KKTMG 1013 Query: 499 GTP-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRL 326 P WMA E L K DV+SFGV+LWE++++ P+ G+ A++ + Q R+ Sbjct: 1014 RLPVRWMAIESLNYSVYTTKSDVWSFGVLLWEIVSLGGTPYCGMTCAELYEKLP-QGYRM 1072 Query: 325 PIPKDTIPELAALVESCWADDPRQRPSFSSI 233 P++ E+ L+ CW D P +RP F+ I Sbjct: 1073 EQPRNCDDEVYELMRQCWRDRPYERPPFAQI 1103
>TESK2_RAT (Q924U5) Dual specificity testis-specific protein kinase 2 (EC| 2.7.12.1) (Testicular protein kinase 2) Length = 570 Score = 84.7 bits (208), Expect = 2e-16 Identities = 60/160 (37%), Positives = 84/160 (52%), Gaps = 8/160 (5%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKN---WSVKVGDFGLSRFKATTFISSK 509 ++A D+A G++YLH I H DL + N L+ ++ +S V DFGL+ I S+ Sbjct: 155 KLAYDIAVGLSYLHFKG--IFHRDLTSKNCLIKRDENGYSAVVADFGLAEKIPDASIGSE 212 Query: 508 SVA--GTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQPWGGLGPAQV---VGAVA 344 +A G+P WMAPE LR EP NEK DV+S+G+IL E++ Q P + A Sbjct: 213 KLAVVGSPFWMAPEVLRDEPYNEKADVFSYGIILCEIIARIQADPDYLPRTENFGLDYDA 272 Query: 343 FQNRRLPIPKDTIPELAALVESCWADDPRQRPSFSSIVDT 224 FQ+ P D + L +C DP+ RPSF I T Sbjct: 273 FQHMVGDCPSDFL----QLTFNCCNMDPKLRPSFEEIGKT 308
>TESK2_MOUSE (Q8VCT9) Dual specificity testis-specific protein kinase 2 (EC| 2.7.12.1) (Testicular protein kinase 2) Length = 570 Score = 84.7 bits (208), Expect = 2e-16 Identities = 60/160 (37%), Positives = 83/160 (51%), Gaps = 8/160 (5%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKN---WSVKVGDFGLSRFKATTFISSK 509 ++A D+A G++YLH I H DL + N L+ ++ +S V DFGL+ I + Sbjct: 155 KLAYDIAVGLSYLHFKG--IFHRDLTSKNCLIKRDENGYSAVVADFGLAEKIPDASIGRE 212 Query: 508 SVA--GTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQPWGGLGPAQV---VGAVA 344 +A G+P WMAPE LR EP NEK DV+S+G+IL E++ Q P + A Sbjct: 213 KLAVVGSPFWMAPEVLRDEPYNEKADVFSYGIILCEIIARIQADPDYLPRTENFGLDYDA 272 Query: 343 FQNRRLPIPKDTIPELAALVESCWADDPRQRPSFSSIVDT 224 FQN P D + L +C DP+ RPSF I T Sbjct: 273 FQNMVGDCPSDFL----QLTFNCCNMDPKLRPSFEEIGKT 308
>TIE1_MOUSE (Q06806) Tyrosine-protein kinase receptor Tie-1 precursor (EC| 2.7.10.1) Length = 1134 Score = 84.7 bits (208), Expect = 2e-16 Identities = 54/151 (35%), Positives = 81/151 (53%), Gaps = 2/151 (1%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVA 500 R A D A G+ YL +H DL N+LV +N + K+ DFGLSR + K++ Sbjct: 954 RFASDAANGMQYL--SEKQFIHRDLAARNVLVGENLASKIADFGLSRGEEVYV--KKTMG 1009 Query: 499 GTP-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRL 326 P WMA E L K DV+SFGV+LWE++++ P+ G+ A++ + Q R+ Sbjct: 1010 RLPVRWMAIESLNYSVYTTKSDVWSFGVLLWEIVSLGGTPYCGMTCAELYEKLP-QGYRM 1068 Query: 325 PIPKDTIPELAALVESCWADDPRQRPSFSSI 233 P++ E+ L+ CW D P +RP F+ I Sbjct: 1069 EQPRNCDDEVYELMRQCWRDRPYERPPFAQI 1099
>VGFR2_COTJA (P52583) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Endothelial kinase receptor EK1) (Quek 1) (Quek1) Length = 1348 Score = 84.7 bits (208), Expect = 2e-16 Identities = 49/152 (32%), Positives = 81/152 (53%), Gaps = 3/152 (1%) Frame = -1 Query: 673 ALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSR--FKATTFISSKSVA 500 + VA+G+ +L + +H DL N+L+ N VK+ DFGL+R +K ++ Sbjct: 1002 SFQVARGMEFL--ASRKCIHRDLAARNILLSDNNVVKICDFGLARDIYKDPDYVRKGDAR 1059 Query: 499 GTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRLP 323 +WMAPE + + DV+SFGV+LWE+ ++ P+ G+ + + R+ Sbjct: 1060 LPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMR 1119 Query: 322 IPKDTIPELAALVESCWADDPRQRPSFSSIVD 227 P T PE+ + CW DP+QRP+FS +V+ Sbjct: 1120 APDYTTPEMYQTMLDCWHGDPKQRPTFSELVE 1151
>MET_HUMAN (P08581) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1390 Score = 84.3 bits (207), Expect = 3e-16 Identities = 57/151 (37%), Positives = 79/151 (52%), Gaps = 4/151 (2%) Frame = -1 Query: 670 LDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRF---KATTFISSKSVA 500 L VAKG+ YL + VH DL N ++D+ ++VKV DFGL+R K + +K+ A Sbjct: 1186 LQVAKGMKYL--ASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGA 1243 Query: 499 GTP-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQPWGGLGPAQVVGAVAFQNRRLP 323 P +WMA E L+ + K DV+SFGV+LWEL+T P + Q RRL Sbjct: 1244 KLPVKWMALESLQTQKFTTKSDVWSFGVVLWELMTRGAPPYPDVNTFDITVYLLQGRRLL 1303 Query: 322 IPKDTIPELAALVESCWADDPRQRPSFSSIV 230 P+ L ++ CW RPSFS +V Sbjct: 1304 QPEYCPDPLYEVMLKCWHPKAEMRPSFSELV 1334
>VGFR1_RAT (P53767) Vascular endothelial growth factor receptor 1 precursor (EC| 2.7.10.1) (VEGFR-1) (Tyrosine-protein kinase receptor FLT) (FLT-1) Length = 1336 Score = 84.3 bits (207), Expect = 3e-16 Identities = 46/152 (30%), Positives = 85/152 (55%), Gaps = 3/152 (1%) Frame = -1 Query: 673 ALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSR--FKATTFISSKSVA 500 + VA+G+ +L + +H DL N+L+ +N VK+ DFGL+R +K ++ Sbjct: 1003 SFQVARGMEFL--SSRKCIHRDLAARNILLSENNVVKICDFGLARDIYKNPDYVRRGDTR 1060 Query: 499 GTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRLP 323 +WMAPE + + + K DV+S+GV+LWE+ ++ P+ G+ + + + R+ Sbjct: 1061 LPLKWMAPESIFDKVYSTKSDVWSYGVLLWEIFSLGGSPYPGVQMDEDFCSRLKEGMRMR 1120 Query: 322 IPKDTIPELAALVESCWADDPRQRPSFSSIVD 227 P+ PE+ ++ CW DP++RP F+ +V+ Sbjct: 1121 TPEYATPEIYQIMLDCWHKDPKERPRFAELVE 1152
>TESK2_HUMAN (Q96S53) Dual specificity testis-specific protein kinase 2 (EC| 2.7.12.1) (Testicular protein kinase 2) Length = 571 Score = 84.3 bits (207), Expect = 3e-16 Identities = 59/160 (36%), Positives = 85/160 (53%), Gaps = 8/160 (5%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKN---WSVKVGDFGLSRFKATTFISSK 509 ++A D+A G++YLH I H DL + N L+ ++ +S V DFGL+ + S+ Sbjct: 155 KLAYDIAVGLSYLHFKG--IFHRDLTSKNCLIKRDENGYSAVVADFGLAEKIPDVSMGSE 212 Query: 508 SVA--GTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQPWGGLGPAQV---VGAVA 344 +A G+P WMAPE LR EP NEK DV+S+G+IL E++ Q P + A Sbjct: 213 KLAVVGSPFWMAPEVLRDEPYNEKADVFSYGIILCEIIARIQADPDYLPRTENFGLDYDA 272 Query: 343 FQNRRLPIPKDTIPELAALVESCWADDPRQRPSFSSIVDT 224 FQ+ + D P+ L +C DP+ RPSF I T Sbjct: 273 FQH----MVGDCPPDFLQLTFNCCNMDPKLRPSFVEIGKT 308
>FYN_XIPHE (P27446) Proto-oncogene tyrosine-protein kinase FYN (EC 2.7.10.2)| (P59-FYN) Length = 536 Score = 84.3 bits (207), Expect = 3e-16 Identities = 53/147 (36%), Positives = 80/147 (54%), Gaps = 2/147 (1%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAG 497 MA VA G+ Y+ N +H DL++ N+LV N K+ DFGL+R +++ A Sbjct: 369 MAAQVAAGMAYIERMN--YIHRDLRSANILVGDNLVCKIADFGLARLIEDNEYTARQGAK 426 Query: 496 TP-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQ-PWGGLGPAQVVGAVAFQNRRLP 323 P +W APE K DV+SFG++L EL+T + P+ G+ +V+ V + R+P Sbjct: 427 FPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVE-RGYRMP 485 Query: 322 IPKDTIPELAALVESCWADDPRQRPSF 242 P+D L L+ CW DP +RP+F Sbjct: 486 CPQDCPASLHELMLQCWKKDPEERPTF 512
>VGFR1_MOUSE (P35969) Vascular endothelial growth factor receptor 1 precursor (EC| 2.7.10.1) (VEGFR-1) (Tyrosine-protein kinase receptor FLT) (FLT-1) (Embryonic receptor kinase 2) Length = 1333 Score = 84.3 bits (207), Expect = 3e-16 Identities = 46/152 (30%), Positives = 85/152 (55%), Gaps = 3/152 (1%) Frame = -1 Query: 673 ALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSR--FKATTFISSKSVA 500 + VA+G+ +L + +H DL N+L+ +N VK+ DFGL+R +K ++ Sbjct: 1003 SFQVARGMEFL--SSRKCIHRDLAARNILLSENNVVKICDFGLARDIYKNPDYVRRGDTR 1060 Query: 499 GTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRLP 323 +WMAPE + + + K DV+S+GV+LWE+ ++ P+ G+ + + + R+ Sbjct: 1061 LPLKWMAPESIFDKVYSTKSDVWSYGVLLWEIFSLGGSPYPGVQMDEDFCSRLKEGMRMR 1120 Query: 322 IPKDTIPELAALVESCWADDPRQRPSFSSIVD 227 P+ PE+ ++ CW DP++RP F+ +V+ Sbjct: 1121 TPEYATPEIYQIMLDCWHKDPKERPRFAELVE 1152
>MOS_PIG (P50118) Proto-oncogene serine/threonine-protein kinase mos (EC| 2.7.11.1) (c-mos) (Oocyte maturation factor mos) Length = 345 Score = 84.3 bits (207), Expect = 3e-16 Identities = 51/151 (33%), Positives = 78/151 (51%), Gaps = 6/151 (3%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLS-RFKATTFISSKSV 503 + +LDV G+ +LH IVH DLK N+L+ + K+ DFG S R + F + Sbjct: 181 KYSLDVVSGLLFLHSQG--IVHLDLKPANILISEQDVCKISDFGCSERLEDLRFRPRHHL 238 Query: 502 AGTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQPWGGLGPAQVVGAVAFQNR--- 332 GT APE L+GEP K D+YSF + LW++ T Q P+ G + VA+ R Sbjct: 239 GGTYTHRAPELLKGEPVTPKADIYSFAITLWQMTTRQVPYSGERQHVLYAVVAYNLRPSL 298 Query: 331 RLPIPKDTIP--ELAALVESCWADDPRQRPS 245 + +++P +L +++ W +QRPS Sbjct: 299 SAAVFTESVPGKKLEDIIQCGWTAPAQQRPS 329
>RON_MOUSE (Q62190) Macrophage-stimulating protein receptor precursor (EC| 2.7.10.1) (MSP receptor) (p185-Ron) (Stem cell-derived tyrosine kinase) (CDw136 antigen) [Contains: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating prote Length = 1378 Score = 84.3 bits (207), Expect = 3e-16 Identities = 59/152 (38%), Positives = 82/152 (53%), Gaps = 5/152 (3%) Frame = -1 Query: 670 LDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRF---KATTFISSKSVA 500 L VA G+ YL VH DL N ++D++++VKV DFGL+R K + A Sbjct: 1167 LQVACGMEYL--AEQKFVHRDLAARNCMLDESFTVKVADFGLARGVLDKEYYSVRQHRHA 1224 Query: 499 GTP-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRL 326 P +WMA E L+ K DV+SFGV+LWELLT P+ + P + +A Q RRL Sbjct: 1225 RLPVKWMALESLQTYRFTTKSDVWSFGVLLWELLTRGAPPYPHIDPFDLSHFLA-QGRRL 1283 Query: 325 PIPKDTIPELAALVESCWADDPRQRPSFSSIV 230 P P+ L ++ CW DP RP+F ++V Sbjct: 1284 PQPEYCPDSLYHVMLRCWEADPAARPTFRALV 1315
>BTKL_DROME (P08630) Tyrosine-protein kinase Btk29A (EC 2.7.10.2) (Dsrc28C)| Length = 786 Score = 84.3 bits (207), Expect = 3e-16 Identities = 52/152 (34%), Positives = 80/152 (52%), Gaps = 2/152 (1%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAG 497 M + V+KG+ YL N +H DL N LV VKV DFGL+R+ +S Sbjct: 627 MCIQVSKGMTYLERHN--YIHRDLAARNCLVGSENVVKVADFGLARYVLDDQYTSSGGTK 684 Query: 496 TP-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRLP 323 P +W PE L + K DV+++GV++WE+ T + P+G L +VV V + L Sbjct: 685 FPIKWAPPEVLNYTRFSSKSDVWAYGVLMWEIFTCGKMPYGRLKNTEVVERVQ-RGIILE 743 Query: 322 IPKDTIPELAALVESCWADDPRQRPSFSSIVD 227 PK E+ +++ CW+ P +RP+F ++D Sbjct: 744 KPKSCAKEIYDVMKLCWSHGPEERPAFRVLMD 775
>VGFR1_HUMAN (P17948) Vascular endothelial growth factor receptor 1 precursor (EC| 2.7.10.1) (VEGFR-1) (Vascular permeability factor receptor) (Tyrosine-protein kinase receptor FLT) (Flt-1) (Tyrosine-protein kinase FRT) (Fms-like tyrosine kinase 1) Length = 1338 Score = 84.3 bits (207), Expect = 3e-16 Identities = 46/152 (30%), Positives = 86/152 (56%), Gaps = 3/152 (1%) Frame = -1 Query: 673 ALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSR--FKATTFISSKSVA 500 + VA+G+ +L + +H DL N+L+ +N VK+ DFGL+R +K ++ Sbjct: 1003 SFQVARGMEFL--SSRKCIHRDLAARNILLSENNVVKICDFGLARDIYKNPDYVRKGDTR 1060 Query: 499 GTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRLP 323 +WMAPE + + + K DV+S+GV+LWE+ ++ P+ G+ + + + R+ Sbjct: 1061 LPLKWMAPESIFDKIYSTKSDVWSYGVLLWEIFSLGGSPYPGVQMDEDFCSRLREGMRMR 1120 Query: 322 IPKDTIPELAALVESCWADDPRQRPSFSSIVD 227 P+ + PE+ ++ CW DP++RP F+ +V+ Sbjct: 1121 APEYSTPEIYQIMLDCWHRDPKERPRFAELVE 1152
>ABL1_HUMAN (P00519) Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2)| (p150) (c-ABL) (Abelson murine leukemia viral oncogene homolog 1) Length = 1130 Score = 84.0 bits (206), Expect = 4e-16 Identities = 53/150 (35%), Positives = 81/150 (54%), Gaps = 2/150 (1%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAG 497 MA ++ + YL N +H DL N LV +N VKV DFGLSR ++ + A Sbjct: 343 MATQISSAMEYLEKKN--FIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAK 400 Query: 496 TP-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRLP 323 P +W APE L + K DV++FGV+LWE+ T P+ G+ +QV + ++ R+ Sbjct: 401 FPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLE-KDYRME 459 Query: 322 IPKDTIPELAALVESCWADDPRQRPSFSSI 233 P+ ++ L+ +CW +P RPSF+ I Sbjct: 460 RPEGCPEKVYELMRACWQWNPSDRPSFAEI 489
>TIE2_BOVIN (Q06807) Angiopoietin-1 receptor precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor TIE-2) (CD202b antigen) Length = 1125 Score = 84.0 bits (206), Expect = 4e-16 Identities = 53/150 (35%), Positives = 82/150 (54%), Gaps = 2/150 (1%) Frame = -1 Query: 673 ALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAGT 494 A DVA+G++YL +H DL N+LV +N+ K+ DFGLSR K++ Sbjct: 946 AADVARGMDYL--SQKQFIHRDLAARNILVGENYVAKIADFGLSR--GQEVYVKKTMGRL 1001 Query: 493 P-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRLPI 320 P WMA E L DV+S+GV+LWE++++ P+ G+ A++ + Q RL Sbjct: 1002 PVRWMAIESLNYSVYTTNSDVWSYGVLLWEIVSLGGTPYCGMTCAELYEKLP-QGYRLEK 1060 Query: 319 PKDTIPELAALVESCWADDPRQRPSFSSIV 230 P + E+ L+ CW + P +RPSF+ I+ Sbjct: 1061 PLNCDDEVYDLMRQCWREKPYERPSFAQIL 1090
>BCK1_YEAST (Q01389) Serine/threonine-protein kinase BCK1/SLK1/SSP31 (EC| 2.7.11.1) Length = 1478 Score = 84.0 bits (206), Expect = 4e-16 Identities = 46/155 (29%), Positives = 86/155 (55%), Gaps = 6/155 (3%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSK-SVA 500 + V KG+ YLH I+H D+K N+L+D++ K+ DFG+SR + +S ++ Sbjct: 1283 LTTQVLKGLAYLHSKG--ILHRDMKADNLLLDQDGICKISDFGISRKSKDIYSNSDMTMR 1340 Query: 499 GTPEWMAPEFLRGEPS-NEKCDVYSFGVILWELLTMQQPWGGLGPAQVVGAVAFQNRRLP 323 GT WMAPE + + + K D++S G I+ E+ ++PW L + + P Sbjct: 1341 GTVFWMAPEMVDTKQGYSAKVDIWSLGCIVLEMFAGKRPWSNLEVVAAMFKIGKSKSAPP 1400 Query: 322 IPKDTIPELAAL----VESCWADDPRQRPSFSSIV 230 IP+DT+P ++ + +++C+ +P +RP+ + ++ Sbjct: 1401 IPEDTLPLISQIGRNFLDACFEINPEKRPTANELL 1435
>EPHB4_MOUSE (P54761) Ephrin type-B receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor MDK-2) (Developmental kinase 2) (Tyrosine kinase MYK-1) Length = 987 Score = 84.0 bits (206), Expect = 4e-16 Identities = 52/155 (33%), Positives = 76/155 (49%), Gaps = 6/155 (3%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRF-----KATTFISS 512 M +A G+ YL VH DL N+LV+ N KV DFGLSRF T+ SS Sbjct: 720 MLRGIASGMRYL--AEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEENSSDPTYTSS 777 Query: 511 KSVAGTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQN 335 + W APE + D +S+G+++WE+++ ++P+ + V+ A+ Q+ Sbjct: 778 LGGKISIRWTAPEAIAFRKFTSASDAWSYGIVMWEVMSFGERPYWDMSNQDVINAIE-QD 836 Query: 334 RRLPIPKDTIPELAALVESCWADDPRQRPSFSSIV 230 RLP P D L L+ CW D RP F +V Sbjct: 837 YRLPPPPDCPTSLHQLMLDCWQKDRNARPRFPQVV 871
>ANPRB_BOVIN (P46197) Atrial natriuretic peptide receptor B precursor (ANP-B)| (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor) Length = 1047 Score = 84.0 bits (206), Expect = 4e-16 Identities = 58/161 (36%), Positives = 84/161 (52%), Gaps = 16/161 (9%) Frame = -1 Query: 667 DVAKGINYLHCXNPPIV-HWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFIS-SKSVAGT 494 D+ KG+ +LH N I H LK+ N +VD + +K+ D+GL+ F++T S ++ Sbjct: 626 DLVKGMAFLH--NSIIASHGSLKSSNCVVDSRFVLKITDYGLASFRSTAEPDDSHALYAK 683 Query: 493 PEWMAPEFLRGEP----SNEKCDVYSFGVILWELLTMQQPWG----GLGPAQVVGAVAFQ 338 W APE L G P +K DVYSFG+IL E+ P+ L P ++V V + Sbjct: 684 KLWTAPELLSGNPLPTTGMQKADVYSFGIILQEIALRSGPFYLEGLDLSPKEIVQKV--R 741 Query: 337 NRRLPIPKDTIP------ELAALVESCWADDPRQRPSFSSI 233 N + P + +I EL L+E CWA DP +RP F I Sbjct: 742 NGQRPYFRPSIDRTQLNEELVLLMERCWAQDPAERPDFGQI 782
>MUSK_HUMAN (O15146) Muscle, skeletal receptor tyrosine protein kinase precursor| (EC 2.7.10.1) (Muscle-specific tyrosine protein kinase receptor) (Muscle-specific kinase receptor) (MuSK) Length = 869 Score = 84.0 bits (206), Expect = 4e-16 Identities = 56/151 (37%), Positives = 83/151 (54%), Gaps = 3/151 (1%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSR--FKATTFISSKSV 503 +A VA G+ YL VH DL T N LV +N VK+ DFGLSR + A + ++++ Sbjct: 705 IARQVAAGMAYL--SERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYSADYYKANEND 762 Query: 502 AGTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRL 326 A WM PE + + DV+++GV+LWE+ + QP+ G+ +V+ V N L Sbjct: 763 AIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGN-IL 821 Query: 325 PIPKDTIPELAALVESCWADDPRQRPSFSSI 233 P++ EL L+ CW+ P RPSF+SI Sbjct: 822 SCPENCPVELYNLMRLCWSKLPADRPSFTSI 852
>UFO_HUMAN (P30530) Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1)| (AXL oncogene) Length = 887 Score = 84.0 bits (206), Expect = 4e-16 Identities = 50/148 (33%), Positives = 78/148 (52%), Gaps = 3/148 (2%) Frame = -1 Query: 667 DVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSR--FKATTFISSKSVAGT 494 D+A G+ YL +H DL N ++++N SV V DFGLS+ + + + Sbjct: 648 DIASGMEYLSTKR--FIHRDLAARNCMLNENMSVCVADFGLSKKIYNGDYYRQGRIAKMP 705 Query: 493 PEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRLPIP 317 +W+A E L K DV+SFGV +WE+ T Q P+ G+ +++ + Q RL P Sbjct: 706 VKWIAIESLADRVYTSKSDVWSFGVTMWEIATRGQTPYPGVENSEIYDYLR-QGNRLKQP 764 Query: 316 KDTIPELAALVESCWADDPRQRPSFSSI 233 D + L AL+ CW +P+ RPSF+ + Sbjct: 765 ADCLDGLYALMSRCWELNPQDRPSFTEL 792
>SRC_RSVSA (P00524) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 84.0 bits (206), Expect = 4e-16 Identities = 54/147 (36%), Positives = 79/147 (53%), Gaps = 2/147 (1%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAG 497 MA +A G+ Y+ N VH DL+ N+LV +N KV DFGL+R +++ A Sbjct: 365 MAAQIASGMAYVERMN--YVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAK 422 Query: 496 TP-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRLP 323 P +W APE K DV+SFG++L EL T + P+ G+G +V+ V + R+P Sbjct: 423 FPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMGNGEVLDRVE-RGYRMP 481 Query: 322 IPKDTIPELAALVESCWADDPRQRPSF 242 P + L L+ CW DP +RP+F Sbjct: 482 CPPECPESLHDLMCQCWRRDPEERPTF 508
>SRC_AVISR (P00525) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 84.0 bits (206), Expect = 4e-16 Identities = 54/147 (36%), Positives = 79/147 (53%), Gaps = 2/147 (1%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAG 497 MA +A G+ Y+ N VH DL+ N+LV +N KV DFGL+R +++ A Sbjct: 365 MAAQIASGMAYVERMN--YVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAK 422 Query: 496 TP-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRLP 323 P +W APE K DV+SFG++L EL T + P+ G+G +V+ V + R+P Sbjct: 423 FPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMGNGEVLDRVE-RGYRMP 481 Query: 322 IPKDTIPELAALVESCWADDPRQRPSF 242 P + L L+ CW DP +RP+F Sbjct: 482 CPPECPESLHDLMCQCWRRDPEERPTF 508
>TIE1_BOVIN (Q06805) Tyrosine-protein kinase receptor Tie-1 precursor (EC| 2.7.10.1) Length = 1136 Score = 84.0 bits (206), Expect = 4e-16 Identities = 54/151 (35%), Positives = 81/151 (53%), Gaps = 2/151 (1%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVA 500 R A D A G+ YL +H DL N+LV +N + K+ DFGLSR + K++ Sbjct: 956 RFASDAANGMQYL--SEKQFIHRDLAARNVLVGENLASKIADFGLSRGEEVYV--KKTMG 1011 Query: 499 GTP-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRL 326 P WMA E L K DV+SFGV+LWE++++ P+ G+ A++ + Q R+ Sbjct: 1012 RLPVRWMAIESLNYSVYTTKSDVWSFGVLLWEIVSLGGTPYCGMTCAELYEKLP-QAYRM 1070 Query: 325 PIPKDTIPELAALVESCWADDPRQRPSFSSI 233 P++ E+ L+ CW D P +RP F+ I Sbjct: 1071 EQPRNCDDEVYELMRQCWRDRPYERPPFAQI 1101
>TIE2_HUMAN (Q02763) Angiopoietin-1 receptor precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen) Length = 1124 Score = 84.0 bits (206), Expect = 4e-16 Identities = 53/150 (35%), Positives = 82/150 (54%), Gaps = 2/150 (1%) Frame = -1 Query: 673 ALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAGT 494 A DVA+G++YL +H DL N+LV +N+ K+ DFGLSR K++ Sbjct: 945 AADVARGMDYL--SQKQFIHRDLAARNILVGENYVAKIADFGLSR--GQEVYVKKTMGRL 1000 Query: 493 P-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRLPI 320 P WMA E L DV+S+GV+LWE++++ P+ G+ A++ + Q RL Sbjct: 1001 PVRWMAIESLNYSVYTTNSDVWSYGVLLWEIVSLGGTPYCGMTCAELYEKLP-QGYRLEK 1059 Query: 319 PKDTIPELAALVESCWADDPRQRPSFSSIV 230 P + E+ L+ CW + P +RPSF+ I+ Sbjct: 1060 PLNCDDEVYDLMRQCWREKPYERPSFAQIL 1089
>MET_CALMO (Q2QLC0) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1381 Score = 84.0 bits (206), Expect = 4e-16 Identities = 57/151 (37%), Positives = 79/151 (52%), Gaps = 4/151 (2%) Frame = -1 Query: 670 LDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRF---KATTFISSKSVA 500 L VAKG+ YL + VH DL N ++D+ ++VKV DFGL+R K + +K+ A Sbjct: 1186 LQVAKGMKYL--ASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGA 1243 Query: 499 GTP-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQPWGGLGPAQVVGAVAFQNRRLP 323 P +WMA E L+ + K DV+SFGV+LWEL+T P + Q RRL Sbjct: 1244 KLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLL 1303 Query: 322 IPKDTIPELAALVESCWADDPRQRPSFSSIV 230 P+ L ++ CW RPSFS +V Sbjct: 1304 QPEYCPDPLYEVMLKCWHPKAEMRPSFSELV 1334
>MET_CALJA (Q2QLG5) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1381 Score = 84.0 bits (206), Expect = 4e-16 Identities = 57/151 (37%), Positives = 79/151 (52%), Gaps = 4/151 (2%) Frame = -1 Query: 670 LDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRF---KATTFISSKSVA 500 L VAKG+ YL + VH DL N ++D+ ++VKV DFGL+R K + +K+ A Sbjct: 1186 LQVAKGMKYL--ASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGA 1243 Query: 499 GTP-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQPWGGLGPAQVVGAVAFQNRRLP 323 P +WMA E L+ + K DV+SFGV+LWEL+T P + Q RRL Sbjct: 1244 KLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLL 1303 Query: 322 IPKDTIPELAALVESCWADDPRQRPSFSSIV 230 P+ L ++ CW RPSFS +V Sbjct: 1304 QPEYCPDPLYEVMLKCWHPKAEMRPSFSELV 1334
>MET_PONPY (Q2IBD8) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1390 Score = 84.0 bits (206), Expect = 4e-16 Identities = 57/151 (37%), Positives = 79/151 (52%), Gaps = 4/151 (2%) Frame = -1 Query: 670 LDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRF---KATTFISSKSVA 500 L VAKG+ YL + VH DL N ++D+ ++VKV DFGL+R K + +K+ A Sbjct: 1186 LQVAKGMKYL--ASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGA 1243 Query: 499 GTP-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQPWGGLGPAQVVGAVAFQNRRLP 323 P +WMA E L+ + K DV+SFGV+LWEL+T P + Q RRL Sbjct: 1244 KLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLL 1303 Query: 322 IPKDTIPELAALVESCWADDPRQRPSFSSIV 230 P+ L ++ CW RPSFS +V Sbjct: 1304 QPEYCPDPLYEVMLKCWHPKAEMRPSFSELV 1334
>MET_PANTR (Q2QLF1) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1390 Score = 84.0 bits (206), Expect = 4e-16 Identities = 57/151 (37%), Positives = 79/151 (52%), Gaps = 4/151 (2%) Frame = -1 Query: 670 LDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRF---KATTFISSKSVA 500 L VAKG+ YL + VH DL N ++D+ ++VKV DFGL+R K + +K+ A Sbjct: 1186 LQVAKGMKYL--ASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGA 1243 Query: 499 GTP-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQPWGGLGPAQVVGAVAFQNRRLP 323 P +WMA E L+ + K DV+SFGV+LWEL+T P + Q RRL Sbjct: 1244 KLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLL 1303 Query: 322 IPKDTIPELAALVESCWADDPRQRPSFSSIV 230 P+ L ++ CW RPSFS +V Sbjct: 1304 QPEYCPDPLYEVMLKCWHPKAEMRPSFSELV 1334
>ABL_MLVAB (P00521) Tyrosine-protein kinase transforming protein Abl (EC| 2.7.10.2) (V-abl) Length = 746 Score = 84.0 bits (206), Expect = 4e-16 Identities = 53/150 (35%), Positives = 81/150 (54%), Gaps = 2/150 (1%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAG 497 MA ++ + YL N +H DL N LV +N VKV DFGLSR ++ + A Sbjct: 229 MATQISSAMEYLEKKN--FIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAK 286 Query: 496 TP-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRLP 323 P +W APE L + K DV++FGV+LWE+ T P+ G+ +QV + ++ R+ Sbjct: 287 FPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLE-KDYRME 345 Query: 322 IPKDTIPELAALVESCWADDPRQRPSFSSI 233 P+ ++ L+ +CW +P RPSF+ I Sbjct: 346 RPEGCPEKVYELMRACWQWNPSDRPSFAEI 375
>ABL1_MOUSE (P00520) Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2)| (p150) (c-ABL) (Abelson murine leukemia viral oncogene homolog 1) Length = 1123 Score = 84.0 bits (206), Expect = 4e-16 Identities = 53/150 (35%), Positives = 81/150 (54%), Gaps = 2/150 (1%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAG 497 MA ++ + YL N +H DL N LV +N VKV DFGLSR ++ + A Sbjct: 343 MATQISSAMEYLEKKN--FIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAK 400 Query: 496 TP-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRLP 323 P +W APE L + K DV++FGV+LWE+ T P+ G+ +QV + ++ R+ Sbjct: 401 FPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLE-KDYRME 459 Query: 322 IPKDTIPELAALVESCWADDPRQRPSFSSI 233 P+ ++ L+ +CW +P RPSF+ I Sbjct: 460 RPEGCPEKVYELMRACWQWNPSDRPSFAEI 489
>MET_MICMU (Q2QL89) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1382 Score = 84.0 bits (206), Expect = 4e-16 Identities = 57/151 (37%), Positives = 79/151 (52%), Gaps = 4/151 (2%) Frame = -1 Query: 670 LDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRF---KATTFISSKSVA 500 L VAKG+ YL + VH DL N ++D+ ++VKV DFGL+R K + +K+ A Sbjct: 1187 LQVAKGMKYL--ASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGA 1244 Query: 499 GTP-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQPWGGLGPAQVVGAVAFQNRRLP 323 P +WMA E L+ + K DV+SFGV+LWEL+T P + Q RRL Sbjct: 1245 KLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLL 1304 Query: 322 IPKDTIPELAALVESCWADDPRQRPSFSSIV 230 P+ L ++ CW RPSFS +V Sbjct: 1305 QPEYCPDPLYEVMLKCWHPKAEMRPSFSELV 1335
>TIE2_MOUSE (Q02858) Angiopoietin-1 receptor precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen) Length = 1122 Score = 84.0 bits (206), Expect = 4e-16 Identities = 53/150 (35%), Positives = 82/150 (54%), Gaps = 2/150 (1%) Frame = -1 Query: 673 ALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAGT 494 A DVA+G++YL +H DL N+LV +N+ K+ DFGLSR K++ Sbjct: 943 AADVARGMDYL--SQKQFIHRDLAARNILVGENYIAKIADFGLSR--GQEVYVKKTMGRL 998 Query: 493 P-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRLPI 320 P WMA E L DV+S+GV+LWE++++ P+ G+ A++ + Q RL Sbjct: 999 PVRWMAIESLNYSVYTTNSDVWSYGVLLWEIVSLGGTPYCGMTCAELYEKLP-QGYRLEK 1057 Query: 319 PKDTIPELAALVESCWADDPRQRPSFSSIV 230 P + E+ L+ CW + P +RPSF+ I+ Sbjct: 1058 PLNCDDEVYDLMRQCWREKPYERPSFAQIL 1087
>NTRK1_CHICK (Q91009) High affinity nerve growth factor receptor precursor (EC| 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (Trk-A) (Fragment) Length = 778 Score = 83.6 bits (205), Expect = 5e-16 Identities = 51/146 (34%), Positives = 78/146 (53%), Gaps = 3/146 (2%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSR-FKATTFISSKSV 503 ++A +A G+ YL + VH DL T N LV + VK+GDFG+SR +T + Sbjct: 612 QIATQIASGMVYLASLH--FVHRDLATRNCLVGHDLVVKIGDFGMSRDIYSTDYYRVGGR 669 Query: 502 AGTP-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRR 329 P WM PE + + D++SFGV+LWE+ T +QPW L + + + Q R Sbjct: 670 TMLPIRWMPPESILYRKFTTESDIWSFGVVLWEIFTYGKQPWYQLSNTEAIECIT-QGRE 728 Query: 328 LPIPKDTIPELAALVESCWADDPRQR 251 L P+ E+ +++SCW +P+QR Sbjct: 729 LERPRTCPSEVYDIMQSCWQREPQQR 754
>MUSK_CHICK (Q8AXY6) Muscle, skeletal receptor tyrosine protein kinase precursor| (EC 2.7.10.1) (Muscle-specific tyrosine protein kinase receptor) (Muscle-specific kinase receptor) (MuSK) Length = 947 Score = 83.6 bits (205), Expect = 5e-16 Identities = 56/151 (37%), Positives = 82/151 (54%), Gaps = 3/151 (1%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSR--FKATTFISSKSV 503 +A VA G+ YL VH DL T N LV +N VK+ DFGLSR + A + ++++ Sbjct: 783 IAKQVAAGMAYL--SERKFVHRDLATRNCLVGENMVVKIADFGLSRNMYSADYYKANEND 840 Query: 502 AGTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRL 326 A WM PE + + DV+++GV+LWE+ + QP+ G+ +V+ V N L Sbjct: 841 AIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGMQPYYGMAHEEVIYYVRDGN-IL 899 Query: 325 PIPKDTIPELAALVESCWADDPRQRPSFSSI 233 P + EL L+ CW+ P RPSF+SI Sbjct: 900 SCPDNCPLELYNLMRLCWSKLPADRPSFASI 930
>EPHA1_HUMAN (P21709) Ephrin type-A receptor 1 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH) Length = 976 Score = 83.6 bits (205), Expect = 5e-16 Identities = 53/152 (34%), Positives = 79/152 (51%), Gaps = 4/152 (2%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAG 497 M +A G+NYL N VH DL N+LV++N KV DFGL+R F + G Sbjct: 729 MLQGIASGMNYL--SNHNYVHRDLAARNILVNQNLCCKVSDFGLTRL-LDDFDGTYETQG 785 Query: 496 TP---EWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRR 329 W APE + DV+SFG+++WE+L+ +P+G + +V+ ++ R Sbjct: 786 GKIPIRWTAPEAIAHRIFTTASDVWSFGIVMWEVLSFGDKPYGEMSNQEVMKSIE-DGYR 844 Query: 328 LPIPKDTIPELAALVESCWADDPRQRPSFSSI 233 LP P D L L+++CWA D +RP F + Sbjct: 845 LPPPVDCPAPLYELMKNCWAYDRARRPHFQKL 876
>INSR_DROME (P09208) Insulin-like receptor precursor (EC 2.7.10.1) (DIR) (DInr)| (dIRH) [Contains: Insulin-like receptor alpha subunit; Insulin-like receptor beta 1 subunit; Insulin-like receptor beta 2 subunit] Length = 2144 Score = 83.6 bits (205), Expect = 5e-16 Identities = 55/153 (35%), Positives = 79/153 (51%), Gaps = 3/153 (1%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVA 500 +MA+++A G+ YL VH DL N +V + +VK+GDFG++R T K Sbjct: 1498 QMAIEIADGMAYLAAKK--FVHRDLAARNCMVADDLTVKIGDFGMTRDIYETDYYRKGTK 1555 Query: 499 GT--PEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRR 329 G WM PE LR + DV+SFGV+LWE+ T+ QP+ GL QV+ V Sbjct: 1556 GLLPVRWMPPESLRDGVYSSASDVFSFGVVLWEMATLAAQPYQGLSNEQVLRYV-IDGGV 1614 Query: 328 LPIPKDTIPELAALVESCWADDPRQRPSFSSIV 230 + P++ L L++ CW RPSF I+ Sbjct: 1615 MERPENCPDFLHKLMQRCWHHRSSARPSFLDII 1647
>BMX_MOUSE (P97504) Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2)| (Bone marrow tyrosine kinase gene in chromosome X protein homolog) Length = 651 Score = 83.6 bits (205), Expect = 5e-16 Identities = 49/151 (32%), Positives = 83/151 (54%), Gaps = 2/151 (1%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATT-FISSKSVA 500 M DV +G+ +L +H DL N LVD + SVKV DFG++R+ ++SS Sbjct: 492 MCYDVCEGMAFLESHQ--FIHRDLAARNCLVDSDLSVKVSDFGMTRYVLDDQYVSSVGTK 549 Query: 499 GTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRLP 323 +W APE + K DV++FG+++WE+ ++ +QP+ ++VV V+ Q RL Sbjct: 550 FPVKWSAPEVFHYFKYSSKSDVWAFGILMWEVFSLGKQPYDLYDNSEVVVKVS-QGHRLY 608 Query: 322 IPKDTIPELAALVESCWADDPRQRPSFSSIV 230 P+ + ++ SCW + P +RP+F ++ Sbjct: 609 RPQLASDTIYQIMYSCWHELPEKRPTFQQLL 639
>WNK2_HUMAN (Q9Y3S1) Serine/threonine-protein kinase WNK2 (EC 2.7.11.1)| (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2) Length = 2297 Score = 83.6 bits (205), Expect = 5e-16 Identities = 50/140 (35%), Positives = 75/140 (53%), Gaps = 2/140 (1%) Frame = -1 Query: 664 VAKGINYLHCXNPPIVHWDLKTPNMLV-DKNWSVKVGDFGLSRFKATTFISSKSVAGTPE 488 + KG+ +LH PPI+H DLK N+ + SVK+GD GL+ K +F +KSV GTPE Sbjct: 305 ILKGLLFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASF--AKSVIGTPE 362 Query: 487 WMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQPWGGL-GPAQVVGAVAFQNRRLPIPKD 311 +MAPE E +E DVY+FG+ + E+ T + P+ AQ+ V + K Sbjct: 363 FMAPEMYE-EHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTCGIKPASFEKV 421 Query: 310 TIPELAALVESCWADDPRQR 251 PE+ ++ C + +R Sbjct: 422 HDPEIKEIIGECICKNKEER 441
>UFO_MOUSE (Q00993) Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1)| (Adhesion-related kinase) Length = 888 Score = 83.6 bits (205), Expect = 5e-16 Identities = 50/148 (33%), Positives = 78/148 (52%), Gaps = 3/148 (2%) Frame = -1 Query: 667 DVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSR--FKATTFISSKSVAGT 494 D+A G+ YL +H DL N ++++N SV V DFGLS+ + + + Sbjct: 649 DIASGMEYLSTKR--FIHRDLAARNCMLNENMSVCVADFGLSKKIYNGDYYRQGRIAKMP 706 Query: 493 PEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRLPIP 317 +W+A E L K DV+SFGV +WE+ T Q P+ G+ +++ + Q RL P Sbjct: 707 VKWIAIESLADRVYTSKSDVWSFGVTMWEIATRGQTPYPGVENSEIYDYLR-QGNRLKQP 765 Query: 316 KDTIPELAALVESCWADDPRQRPSFSSI 233 D + L +L+ CW +PR RPSF+ + Sbjct: 766 VDFLDGLYSLMSRCWELNPRDRPSFAEL 793
>MET_MOUSE (P16056) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1379 Score = 83.6 bits (205), Expect = 5e-16 Identities = 57/151 (37%), Positives = 79/151 (52%), Gaps = 4/151 (2%) Frame = -1 Query: 670 LDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRF---KATTFISSKSVA 500 L VAKG+ YL + VH DL N ++D+ ++VKV DFGL+R K + +K+ A Sbjct: 1184 LQVAKGMKYL--ASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGA 1241 Query: 499 GTP-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQPWGGLGPAQVVGAVAFQNRRLP 323 P +WMA E L+ + K DV+SFGV+LWEL+T P + Q RRL Sbjct: 1242 KLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITIYLLQGRRLL 1301 Query: 322 IPKDTIPELAALVESCWADDPRQRPSFSSIV 230 P+ L ++ CW RPSFS +V Sbjct: 1302 QPEYCPDALYEVMLKCWHPKAEMRPSFSELV 1332
>FGFR4_RAT (Q498D6) Fibroblast growth factor receptor 4 precursor (EC 2.7.10.1)| (FGFR-4) Length = 800 Score = 83.6 bits (205), Expect = 5e-16 Identities = 51/152 (33%), Positives = 81/152 (53%), Gaps = 3/152 (1%) Frame = -1 Query: 673 ALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAGT 494 A VA+G+ YL +H DL N+LV ++ +K+ DFGL+R K+ G Sbjct: 591 AYQVARGMQYLESRK--CIHRDLAARNVLVTEDDVMKIADFGLARGVHHIDYYKKTSNGR 648 Query: 493 --PEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRLP 323 +WMAPE L + DV+SFG++LWE+ T+ P+ G+ P + + ++ + R+ Sbjct: 649 LPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGI-PVEELFSLLREGHRME 707 Query: 322 IPKDTIPELAALVESCWADDPRQRPSFSSIVD 227 P + EL L+ CW P QRP+F +V+ Sbjct: 708 RPPNCPSELYGLMRECWHAAPSQRPTFKQLVE 739
>FAK2_MOUSE (Q9QVP9) Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal| adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinas Length = 1009 Score = 83.6 bits (205), Expect = 5e-16 Identities = 54/149 (36%), Positives = 76/149 (51%), Gaps = 2/149 (1%) Frame = -1 Query: 670 LDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAGTP 491 L + K + YL N VH D+ N+LV VK+GDFGLSR+ SV P Sbjct: 531 LQICKAMAYLESIN--CVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLP 588 Query: 490 -EWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRLPIP 317 +WM+PE + DV+ F V +WE+L+ +QP+ L V+G + + RLP P Sbjct: 589 IKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLE-KGDRLPKP 647 Query: 316 KDTIPELAALVESCWADDPRQRPSFSSIV 230 + P L L+ CW DP RP F+ +V Sbjct: 648 ELCPPVLYTLMTRCWDYDPSDRPRFTELV 676
>SRK1_SPOLA (P42686) Tyrosine-protein kinase isoform SRK1 (EC 2.7.10.2)| Length = 505 Score = 83.6 bits (205), Expect = 5e-16 Identities = 51/150 (34%), Positives = 82/150 (54%), Gaps = 2/150 (1%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAG 497 +A VA G++YL N +H DL N+LV ++ KV DFGL+R + + A Sbjct: 339 VAAQVASGMSYLEQQN--YIHRDLAARNILVGEHGICKVADFGLARVIDEEIYEAHTGAK 396 Query: 496 TP-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQ-PWGGLGPAQVVGAVAFQNRRLP 323 P +W APE K DV+SFGV+L+E++T + P+ G+ +V+ + QN R+P Sbjct: 397 FPIKWTAPEAAMYNRFTIKSDVWSFGVVLYEIITYGRFPYPGMTNPEVLEKIQ-QNYRMP 455 Query: 322 IPKDTIPELAALVESCWADDPRQRPSFSSI 233 P + + ++ CW +DP RP+F ++ Sbjct: 456 CPANCPKQFHDIMLDCWREDPASRPTFETL 485
>FAK2_HUMAN (Q14289) Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal| adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinas Length = 1009 Score = 83.2 bits (204), Expect = 7e-16 Identities = 54/150 (36%), Positives = 76/150 (50%), Gaps = 2/150 (1%) Frame = -1 Query: 673 ALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAGT 494 +L + K + YL N VH D+ N+LV VK+GDFGLSR+ SV Sbjct: 530 SLQICKAMAYLESIN--CVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRL 587 Query: 493 P-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRLPI 320 P +WM+PE + DV+ F V +WE+L+ +QP+ L V+G + + RLP Sbjct: 588 PIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLE-KGDRLPK 646 Query: 319 PKDTIPELAALVESCWADDPRQRPSFSSIV 230 P P L L+ CW DP RP F+ +V Sbjct: 647 PDLCPPVLYTLMTRCWDYDPSDRPRFTELV 676
>ABL_DROME (P00522) Tyrosine-protein kinase Abl (EC 2.7.10.2) (Abelson| protein) (D-ash) Length = 1620 Score = 83.2 bits (204), Expect = 7e-16 Identities = 54/154 (35%), Positives = 76/154 (49%), Gaps = 6/154 (3%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAG 497 MA +A G++YL N +H DL N LV N VKV DFGL+R ++ + A Sbjct: 472 MATQIASGMSYLESRN--YIHRDLAARNCLVGDNKLVKVADFGLARLMRDDTYTAHAGAK 529 Query: 496 TP-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQPWGGLGPAQVVGAVAFQNR---- 332 P +W APE L + K DV++FGV+LWE+ T G+ P + ++ Sbjct: 530 FPIKWTAPEGLAYNKFSTKSDVWAFGVLLWEIATY-----GMSPYPAIDLTDVYHKLDKG 584 Query: 331 -RLPIPKDTIPELAALVESCWADDPRQRPSFSSI 233 R+ P PE+ L+ CW D RP+F SI Sbjct: 585 YRMERPPGCPPEVYDLMRQCWQWDATDRPTFKSI 618
>FYN_XENLA (P13406) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 536 Score = 83.2 bits (204), Expect = 7e-16 Identities = 52/147 (35%), Positives = 81/147 (55%), Gaps = 2/147 (1%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAG 497 MA VA+G+ Y+ N +H DL++ N+LV K+ DFGL+R +++ A Sbjct: 369 MAAQVARGMAYIERMN--YIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAK 426 Query: 496 TP-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQ-PWGGLGPAQVVGAVAFQNRRLP 323 P +W APE K DV+SFG++L EL+T + P+ G+ +V+ V + R+P Sbjct: 427 FPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVE-RGYRMP 485 Query: 322 IPKDTIPELAALVESCWADDPRQRPSF 242 P+D L L+ +CW DP +RP+F Sbjct: 486 CPQDCPISLHELMLNCWKKDPEERPTF 512
>EPHB4_HUMAN (P54760) Ephrin type-B receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor HTK) Length = 987 Score = 83.2 bits (204), Expect = 7e-16 Identities = 52/155 (33%), Positives = 75/155 (48%), Gaps = 6/155 (3%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRF-----KATTFISS 512 M +A G+ YL VH DL N+LV+ N KV DFGLSRF T+ SS Sbjct: 720 MLRGIASGMRYL--AEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEENSSDPTYTSS 777 Query: 511 KSVAGTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQN 335 W APE + D +S+G+++WE+++ ++P+ + V+ A+ Q+ Sbjct: 778 LGGKIPIRWTAPEAIAFRKFTSASDAWSYGIVMWEVMSFGERPYWDMSNQDVINAIE-QD 836 Query: 334 RRLPIPKDTIPELAALVESCWADDPRQRPSFSSIV 230 RLP P D L L+ CW D RP F +V Sbjct: 837 YRLPPPPDCPTSLHQLMLDCWQKDRNARPRFPQVV 871
>NEK4_HUMAN (P51957) Serine/threonine-protein kinase Nek4 (EC 2.7.11.1)| (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2) (Serine/threonine-protein kinase NRK2) Length = 841 Score = 83.2 bits (204), Expect = 7e-16 Identities = 45/147 (30%), Positives = 80/147 (54%) Frame = -1 Query: 670 LDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAGTP 491 + +A + YLH I+H DLKT N+ + + +KVGD G++R + ++ GTP Sbjct: 113 VQIAMALQYLH--EKHILHRDLKTQNVFLTRTNIIKVGDLGIARVLENHCDMASTLIGTP 170 Query: 490 EWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQPWGGLGPAQVVGAVAFQNRRLPIPKD 311 +M+PE +P N K DV++ G ++E+ T++ + +V + + + +P+D Sbjct: 171 YYMSPELFSNKPYNYKSDVWALGCCVYEMATLKHAFNAKDMNSLVYRI-IEGKLPAMPRD 229 Query: 310 TIPELAALVESCWADDPRQRPSFSSIV 230 PELA L+ + + P +RPS SI+ Sbjct: 230 YSPELAELIRTMLSKRPEERPSVRSIL 256
>FGFR3_HUMAN (P22607) Fibroblast growth factor receptor 3 precursor (EC 2.7.10.1)| (FGFR-3) (CD333 antigen) Length = 806 Score = 83.2 bits (204), Expect = 7e-16 Identities = 50/152 (32%), Positives = 81/152 (53%), Gaps = 3/152 (1%) Frame = -1 Query: 673 ALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAGT 494 A VA+G+ YL + +H DL N+LV ++ +K+ DFGL+R K+ G Sbjct: 598 AYQVARGMEYL--ASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGR 655 Query: 493 --PEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRLP 323 +WMAPE L + DV+SFGV+LWE+ T+ P+ G+ P + + + + R+ Sbjct: 656 LPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGI-PVEELFKLLKEGHRMD 714 Query: 322 IPKDTIPELAALVESCWADDPRQRPSFSSIVD 227 P + +L ++ CW P QRP+F +V+ Sbjct: 715 KPANCTHDLYMIMRECWHAAPSQRPTFKQLVE 746
>ANPRB_HUMAN (P20594) Atrial natriuretic peptide receptor B precursor (ANP-B)| (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor) Length = 1047 Score = 83.2 bits (204), Expect = 7e-16 Identities = 58/161 (36%), Positives = 84/161 (52%), Gaps = 16/161 (9%) Frame = -1 Query: 667 DVAKGINYLHCXNPPIV-HWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFIS-SKSVAGT 494 D+ KG+ +LH N I H LK+ N +VD + +K+ D+GL+ F++T S ++ Sbjct: 626 DLVKGMAFLH--NSIISSHGSLKSSNCVVDSRFVLKITDYGLASFRSTAEPDDSHALYAK 683 Query: 493 PEWMAPEFLRGEP----SNEKCDVYSFGVILWELLTMQQPWG----GLGPAQVVGAVAFQ 338 W APE L G P +K DVYSFG+IL E+ P+ L P ++V V + Sbjct: 684 KLWTAPELLSGNPLPTTGMQKADVYSFGIILQEIALRSGPFYLEGLDLSPKEIVQKV--R 741 Query: 337 NRRLPIPKDTIP------ELAALVESCWADDPRQRPSFSSI 233 N + P + +I EL L+E CWA DP +RP F I Sbjct: 742 NGQRPYFRPSIDRTQLNEELVLLMERCWAQDPAERPDFGQI 782
>ABL1_CAEEL (P03949) Tyrosine-protein kinase abl-1 (EC 2.7.10.2)| Length = 1224 Score = 83.2 bits (204), Expect = 7e-16 Identities = 52/151 (34%), Positives = 78/151 (51%), Gaps = 2/151 (1%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRF-KATTFISSKSV 503 +MA +A G++YL + +H DL N LV ++ VK+ DFGL+RF K T+ + Sbjct: 411 QMASQIASGMSYLEARH--FIHRDLAARNCLVSEHNIVKIADFGLARFMKEDTYTAHAGA 468 Query: 502 AGTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRL 326 +W APE L + K DV++FGV+LWE+ T P+ G+ + V G + R+ Sbjct: 469 KFPIKWTAPEGLAFNTFSSKSDVWAFGVLLWEIATYGMAPYPGVELSNVYGLLE-NGFRM 527 Query: 325 PIPKDTIPELAALVESCWADDPRQRPSFSSI 233 P+ P + L+ CW P RP F I Sbjct: 528 DGPQGCPPSVYRLMLQCWNWSPSDRPRFRDI 558
>FLK_RAT (P09760) Tyrosine-protein kinase FLK (EC 2.7.10.2) (Fragment)| Length = 323 Score = 83.2 bits (204), Expect = 7e-16 Identities = 52/151 (34%), Positives = 80/151 (52%), Gaps = 2/151 (1%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVA 500 R +LDVA G+ YL N +H DL N LV +N ++K+ DFG+SR + SS + Sbjct: 164 RFSLDVAAGMLYLEGKN--CIHRDLAARNCLVGENNTLKISDFGMSRQEDGGVYSSSGLK 221 Query: 499 GTP-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQ-PWGGLGPAQVVGAVAFQNRRL 326 P +W APE L + + DV+SFG++LWE ++ P+ G+ Q V + R+ Sbjct: 222 QIPIKWTAPEALNYGRYSSESDVWSFGILLWETFSLGVCPYPGMTNQQAREQVE-RGYRM 280 Query: 325 PIPKDTIPELAALVESCWADDPRQRPSFSSI 233 P++ E+ ++ CW P RP FS + Sbjct: 281 SAPQNCPEEIFTIMMKCWDYKPENRPKFSDL 311
>MET_HORSE (Q2QLA9) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1381 Score = 83.2 bits (204), Expect = 7e-16 Identities = 57/151 (37%), Positives = 79/151 (52%), Gaps = 4/151 (2%) Frame = -1 Query: 670 LDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRF---KATTFISSKSVA 500 L VAKG+ YL + VH DL N ++D+ ++VKV DFGL+R K + +K+ A Sbjct: 1186 LQVAKGMKYL--ASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGA 1243 Query: 499 GTP-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQPWGGLGPAQVVGAVAFQNRRLP 323 P +WMA E L+ + K DV+SFGV+LWEL+T P + Q RRL Sbjct: 1244 KLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLL 1303 Query: 322 IPKDTIPELAALVESCWADDPRQRPSFSSIV 230 P+ L ++ CW RPSFS +V Sbjct: 1304 QPEYCPDPLYEVMLKCWHPKAELRPSFSELV 1334
>SRC42_DROME (Q9V9J3) Tyrosine-protein kinase Src42A (EC 2.7.10.2) (Dsrc41)| Length = 517 Score = 82.8 bits (203), Expect = 9e-16 Identities = 53/150 (35%), Positives = 80/150 (53%), Gaps = 2/150 (1%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAG 497 MA +A G+ YL N +H DL N+LV VK+ DFGL+R ++ A Sbjct: 350 MAAQIAAGMAYLESQN--YIHRDLAARNVLVGDGNIVKIADFGLARLIKEDEYEARVGAR 407 Query: 496 TP-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQ-PWGGLGPAQVVGAVAFQNRRLP 323 P +W APE + K DV+SFG++L EL+T + P+ G+ A+V+ V R+P Sbjct: 408 FPIKWTAPEAANYSKFSIKSDVWSFGILLTELVTYGRIPYPGMTNAEVLTQVE-HGYRMP 466 Query: 322 IPKDTIPELAALVESCWADDPRQRPSFSSI 233 P + P L ++ CW DP +RP+F ++ Sbjct: 467 QPPNCEPRLYEIMLECWHKDPMRRPTFETL 496
>FGFR1_XENLA (P22182) Fibroblast growth factor receptor 1 precursor (EC 2.7.10.1)| (FGFR-1) Length = 812 Score = 82.8 bits (203), Expect = 9e-16 Identities = 51/152 (33%), Positives = 84/152 (55%), Gaps = 3/152 (1%) Frame = -1 Query: 673 ALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAGT 494 A VA+G++YL + +H DL N+LV ++ +K+ DFGL+R K+ G Sbjct: 598 AYQVARGMDYL--ASKKCIHRDLAARNVLVTEDNIMKIADFGLARDIHHIDYYKKTTNGR 655 Query: 493 --PEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRLP 323 +WMAPE L + DV+SFGV+LWE+ T+ P+ G+ P + + + + R+ Sbjct: 656 LPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGV-PMEELFKLLKEGHRMD 714 Query: 322 IPKDTIPELAALVESCWADDPRQRPSFSSIVD 227 P + EL +++ CW P QRP+F+ +V+ Sbjct: 715 KPTNCTNELYMMMKDCWHAMPSQRPTFNQLVE 746
>BMX_HUMAN (P51813) Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2)| (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38) Length = 675 Score = 82.8 bits (203), Expect = 9e-16 Identities = 49/153 (32%), Positives = 83/153 (54%), Gaps = 2/153 (1%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATT-FISSKSVA 500 M DV +G+ +L +H DL N LVD++ VKV DFG++R+ ++SS Sbjct: 516 MCYDVCEGMAFLESHQ--FIHRDLAARNCLVDRDLCVKVSDFGMTRYVLDDQYVSSVGTK 573 Query: 499 GTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRLP 323 +W APE + K DV++FG+++WE+ ++ +QP+ +QVV V+ Q RL Sbjct: 574 FPVKWSAPEVFHYFKYSSKSDVWAFGILMWEVFSLGKQPYDLYDNSQVVLKVS-QGHRLY 632 Query: 322 IPKDTIPELAALVESCWADDPRQRPSFSSIVDT 224 P + ++ SCW + P +RP+F ++ + Sbjct: 633 RPHLASDTIYQIMYSCWHELPEKRPTFQQLLSS 665
>TOR_DROME (P18475) Tyrosine-protein kinase receptor torso precursor (EC| 2.7.10.1) Length = 923 Score = 82.8 bits (203), Expect = 9e-16 Identities = 50/152 (32%), Positives = 85/152 (55%), Gaps = 4/152 (2%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSR--FKATTFISSKSV 503 +A VA G+ +L +VH DL N+L+ + S+K+ DFGLSR + + S Sbjct: 721 IAQQVAVGMEFL--AQNKVVHRDLAARNVLISVDRSIKIADFGLSRDVYHENVYRKSGGS 778 Query: 502 AGTP-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQ-QPWGGLGPAQVVGAVAFQNRR 329 P +W+A E L + + DV+SFGV+L+E+ T+ P+ + P+ ++ + Q R Sbjct: 779 GKLPIKWLALESLTHQVYTSQSDVWSFGVLLYEITTLGGMPYPSVSPSDLLQLLR-QGHR 837 Query: 328 LPIPKDTIPELAALVESCWADDPRQRPSFSSI 233 + P+ E+ +L+ESCW+ P RP+FS++ Sbjct: 838 MKRPEGCTQEMFSLMESCWSSVPSHRPTFSAL 869
>NTRK3_CHICK (Q91044) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (Trk-C) Length = 827 Score = 82.8 bits (203), Expect = 9e-16 Identities = 55/151 (36%), Positives = 78/151 (51%), Gaps = 3/151 (1%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSR-FKATTFISSKSVA 500 +A +A G+ YL + VH DL T N LV N VK+GDFG+SR +T + Sbjct: 661 IASQIASGMVYL--ASQHFVHRDLATRNCLVGANLLVKIGDFGMSRDVYSTDYYRVGGHT 718 Query: 499 GTP-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRL 326 P WM PE + + DV+SFGVILWE+ T +QPW L +V+ + Q R L Sbjct: 719 MLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGKQPWFQLSNTEVIECIT-QGRVL 777 Query: 325 PIPKDTIPELAALVESCWADDPRQRPSFSSI 233 P+ E+ ++ CW +P+QR + I Sbjct: 778 ERPRVCPKEVYDIMLGCWQREPQQRLNIKEI 808
>CEK2_CHICK (P18460) Tyrosine kinase receptor CEK2 precursor (EC 2.7.10.1)| Length = 806 Score = 82.8 bits (203), Expect = 9e-16 Identities = 50/152 (32%), Positives = 81/152 (53%), Gaps = 3/152 (1%) Frame = -1 Query: 673 ALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAGT 494 A VA+G+ YL + +H DL N+LV ++ +K+ DFGL+R K+ G Sbjct: 592 AYQVARGMEYL--ASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNIDYYKKTTNGR 649 Query: 493 --PEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRLP 323 +WMAPE L + DV+SFGV+LWE+ T+ P+ G+ P + + + + R+ Sbjct: 650 LPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGI-PVEELFKLLKEGHRMD 708 Query: 322 IPKDTIPELAALVESCWADDPRQRPSFSSIVD 227 P + +L ++ CW P QRP+F +V+ Sbjct: 709 KPANCTHDLYMIMRECWHAVPSQRPTFKQLVE 740
>TYRO3_RAT (P55146) Tyrosine-protein kinase receptor TYRO3 precursor (EC| 2.7.10.1) (Tyrosine-protein kinase SKY) Length = 880 Score = 82.8 bits (203), Expect = 9e-16 Identities = 50/152 (32%), Positives = 82/152 (53%), Gaps = 3/152 (1%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSR--FKATTFISSKS 506 R +D+A G+ YL N +H DL N ++ ++ +V V DFGLSR + + + Sbjct: 624 RFMVDIACGMEYLSSRN--FIHRDLAARNCMLAEDMTVCVADFGLSRKIYSGDYYRQGCA 681 Query: 505 VAGTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRR 329 +W+A E L DV++FGV +WE++T Q P+ G+ A++ + NR Sbjct: 682 SKLPVKWLALESLADNLYTVHSDVWAFGVTMWEIMTRGQTPYAGIENAEIYNYLISGNR- 740 Query: 328 LPIPKDTIPELAALVESCWADDPRQRPSFSSI 233 L P + + E+ L+ CW+ DP+QRPSF+ + Sbjct: 741 LKQPPECMEEVYDLMYQCWSADPKQRPSFTCL 772
>PHY1_CERPU (P25848) Light-sensor Protein kinase [Includes: Phytochrome; Protein| kinase (EC 2.7.11.1)] Length = 1307 Score = 82.8 bits (203), Expect = 9e-16 Identities = 61/172 (35%), Positives = 83/172 (48%), Gaps = 26/172 (15%) Frame = -1 Query: 670 LDVAKGINYLHCXNPPIVHWDLKTPNMLVDK---------NWSVKVGDFGLSRFK--ATT 524 L ++G+NYLH I+H DLK+ N+LV VKV DFGLS+ K +T Sbjct: 1109 LQTSEGMNYLH--EKGIIHRDLKSMNILVKSVKVTKSEIGYVHVKVADFGLSKTKDSSTR 1166 Query: 523 FISSKSVAGTPEWMAPEFLR-GEPSNE--------------KCDVYSFGVILWELLTMQQ 389 + + GT WMAPE + G S E K DVYSFG++ +E+LT Sbjct: 1167 YSNQTWNRGTNRWMAPEVINLGYESTEGEISFDGKVPKYPLKSDVYSFGMVCYEVLTGDV 1226 Query: 388 PWGGLGPAQVVGAVAFQNRRLPIPKDTIPELAALVESCWADDPRQRPSFSSI 233 P+ V + + R +P EL AL+ CW DP +RPSF+ I Sbjct: 1227 PFPEEKNPNNVKRMVLEGVRPDLPAHCPIELKALITDCWNQDPLKRPSFAVI 1278
>MET_PIG (Q2QLE0) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1381 Score = 82.8 bits (203), Expect = 9e-16 Identities = 57/151 (37%), Positives = 79/151 (52%), Gaps = 4/151 (2%) Frame = -1 Query: 670 LDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRF---KATTFISSKSVA 500 L VAKG+ YL + VH DL N ++D+ ++VKV DFGL+R K + +K+ A Sbjct: 1186 LQVAKGMKYL--ASKKFVHRDLAARNCMLDEKFTVKVADFGLARDVYDKEYYSVHNKTGA 1243 Query: 499 GTP-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQPWGGLGPAQVVGAVAFQNRRLP 323 P +WMA E L+ + K DV+SFGV+LWEL+T P + Q RRL Sbjct: 1244 KLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLL 1303 Query: 322 IPKDTIPELAALVESCWADDPRQRPSFSSIV 230 P+ L ++ CW RPSFS +V Sbjct: 1304 QPEYCPDPLYEVMLKCWHPRAELRPSFSELV 1334
>CEK3_CHICK (P18461) Tyrosine kinase receptor CEK3 precursor (EC 2.7.10.1)| Length = 823 Score = 82.8 bits (203), Expect = 9e-16 Identities = 49/149 (32%), Positives = 80/149 (53%), Gaps = 3/149 (2%) Frame = -1 Query: 664 VAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAGT--P 491 +A+G+ YL + +H DL N+LV +N +K+ DFGL+R K+ G Sbjct: 612 LARGMEYL--ASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPV 669 Query: 490 EWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRLPIPK 314 +WMAPE L + DV+SFGV++WE+ T+ P+ G+ P + + + + R+ P Sbjct: 670 KWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGI-PVEELFKLLKEGHRMDKPA 728 Query: 313 DTIPELAALVESCWADDPRQRPSFSSIVD 227 + EL ++ CW P QRP+F +V+ Sbjct: 729 NCTNELYMMMRDCWQAVPSQRPTFKQLVE 757
>MOS_XENLA (P12965) Serine/threonine-protein kinase mos (EC 2.7.11.1)| (pp39-mos) Length = 359 Score = 82.8 bits (203), Expect = 9e-16 Identities = 55/164 (33%), Positives = 84/164 (51%), Gaps = 13/164 (7%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLS-RFKATTFISS--- 512 R A VA G+ +LH +VH DLK N+L+ K+GDFG S R + + Sbjct: 168 RYARHVADGLRFLH--RDGVVHLDLKPANVLLAPGDLCKIGDFGCSQRLREGDEAAGGEP 225 Query: 511 -----KSVAGTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQPWGGLGPAQVVGAV 347 + V GT APE L+GEP K D+YSF + LW++++ + P+ G + V Sbjct: 226 CCTQLRHVGGTYTHRAPELLKGEPVTAKADIYSFAITLWQMVSRELPYTGDRQCVLYAVV 285 Query: 346 AFQNR--RLPIPKDTIPELAA--LVESCWADDPRQRPSFSSIVD 227 A+ R P+ T AA +V+SCWA P++RP+ +++ Sbjct: 286 AYDLRPEMGPLFSHTEEGRAARTIVQSCWAARPQERPNAEQLLE 329
>MET_CANFA (Q75ZY9) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1382 Score = 82.8 bits (203), Expect = 9e-16 Identities = 57/151 (37%), Positives = 79/151 (52%), Gaps = 4/151 (2%) Frame = -1 Query: 670 LDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRF---KATTFISSKSVA 500 L VAKG+ YL + VH DL N ++D+ ++VKV DFGL+R K + +K+ A Sbjct: 1187 LQVAKGMKYL--ASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGA 1244 Query: 499 GTP-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQPWGGLGPAQVVGAVAFQNRRLP 323 P +WMA E L+ + K DV+SFGV+LWEL+T P + Q RRL Sbjct: 1245 KLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLL 1304 Query: 322 IPKDTIPELAALVESCWADDPRQRPSFSSIV 230 P+ L ++ CW RPSFS +V Sbjct: 1305 QPEYCPDPLYEVMLKCWHPRAELRPSFSELV 1335
>MOS_HUMAN (P00540) Proto-oncogene serine/threonine-protein kinase mos (EC| 2.7.11.1) (c-mos) (Oocyte maturation factor mos) Length = 346 Score = 82.4 bits (202), Expect = 1e-15 Identities = 51/153 (33%), Positives = 76/153 (49%), Gaps = 8/153 (5%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFI---SSK 509 + +LDV G+ +LH + IVH DLK N+L+ + K+ DFG S S Sbjct: 180 KYSLDVVNGLLFLHSQS--IVHLDLKPANILISEQDVCKISDFGCSEKLEDLLCFQTPSY 237 Query: 508 SVAGTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQPWGGLGPAQVVGAVAFQNR- 332 + GT APE L+GE K D+YSF + LW++ T Q P+ G + VA+ R Sbjct: 238 PLGGTYTHRAPELLKGEGVTPKADIYSFAITLWQMTTKQAPYSGERQHILYAVVAYDLRP 297 Query: 331 --RLPIPKDTIP--ELAALVESCWADDPRQRPS 245 + +D++P L +++ CW QRPS Sbjct: 298 SLSAAVFEDSLPGQRLGDVIQRCWRPSAAQRPS 330
>SRC2_XENLA (P13116) Tyrosine-protein kinase Src-2 (EC 2.7.10.2) (p60-Src-2)| Length = 531 Score = 82.4 bits (202), Expect = 1e-15 Identities = 54/147 (36%), Positives = 78/147 (53%), Gaps = 2/147 (1%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAG 497 MA +A G+ Y+ N VH DL+ N+LV +N KV DFGL+R +++ A Sbjct: 364 MAAQIASGMAYVERMN--YVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAK 421 Query: 496 TP-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQ-PWGGLGPAQVVGAVAFQNRRLP 323 P +W APE K DV+SFG++L EL T + P+ G+ +V+ V + R+P Sbjct: 422 FPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVE-RGYRMP 480 Query: 322 IPKDTIPELAALVESCWADDPRQRPSF 242 P D L L+ CW DP +RP+F Sbjct: 481 CPPDCPESLHDLMFQCWRKDPEERPTF 507
>SRC1_XENLA (P13115) Tyrosine-protein kinase Src-1 (EC 2.7.10.2) (p60-Src-1)| Length = 531 Score = 82.4 bits (202), Expect = 1e-15 Identities = 54/147 (36%), Positives = 78/147 (53%), Gaps = 2/147 (1%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAG 497 MA +A G+ Y+ N VH DL+ N+LV +N KV DFGL+R +++ A Sbjct: 364 MAAQIASGMAYVERMN--YVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAK 421 Query: 496 TP-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQ-PWGGLGPAQVVGAVAFQNRRLP 323 P +W APE K DV+SFG++L EL T + P+ G+ +V+ V + R+P Sbjct: 422 FPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVE-RGYRMP 480 Query: 322 IPKDTIPELAALVESCWADDPRQRPSF 242 P D L L+ CW DP +RP+F Sbjct: 481 CPPDCPESLHDLMFQCWRKDPEERPTF 507
>FGFR1_CHICK (P21804) Basic fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) Length = 819 Score = 82.4 bits (202), Expect = 1e-15 Identities = 51/152 (33%), Positives = 81/152 (53%), Gaps = 3/152 (1%) Frame = -1 Query: 673 ALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAGT 494 A VA+G+ YL + +H DL N+LV ++ +K+ DFGL+R K+ G Sbjct: 602 AYQVARGMEYL--ASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGR 659 Query: 493 --PEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRLP 323 +WMAPE L + DV+SFGV+LWE+ T+ P+ G+ P + + + + R+ Sbjct: 660 LPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGV-PVEELFKLLKEGHRMD 718 Query: 322 IPKDTIPELAALVESCWADDPRQRPSFSSIVD 227 P + EL ++ CW P QRP+F +V+ Sbjct: 719 KPSNCTNELYMMMRDCWHAVPSQRPTFKQLVE 750
>FES_FELCA (P14238) Proto-oncogene tyrosine-protein kinase FES/FPS (EC 2.7.10.2)| (C-FES) Length = 820 Score = 82.4 bits (202), Expect = 1e-15 Identities = 55/152 (36%), Positives = 82/152 (53%), Gaps = 3/152 (1%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKAT-TFISSKSV 503 +M D A G+ YL + +H DL N LV + +K+ DFG+SR +A + +S + Sbjct: 660 QMVGDAAAGMEYLE--SKCCIHRDLAARNCLVTEKNVLKISDFGMSREEADGIYAASGGL 717 Query: 502 AGTP-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRR 329 P +W APE L + + DV+SFG++LWE ++ P+ L Q V + R Sbjct: 718 RQVPVKWTAPEALNYGRYSSESDVWSFGILLWETFSLGASPYPNLSNQQTREFVE-KGGR 776 Query: 328 LPIPKDTIPELAALVESCWADDPRQRPSFSSI 233 LP P+ + L+E CWA +P QRPSFS+I Sbjct: 777 LPCPELCPDAVFRLMEQCWAYEPGQRPSFSAI 808
>TYRO3_MOUSE (P55144) Tyrosine-protein kinase receptor TYRO3 precursor (EC| 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase DTK) (TK19-2) (Etk2/tyro3) Length = 880 Score = 82.4 bits (202), Expect = 1e-15 Identities = 50/152 (32%), Positives = 82/152 (53%), Gaps = 3/152 (1%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSR--FKATTFISSKS 506 R +D+A G+ YL N +H DL N ++ ++ +V V DFGLSR + + + Sbjct: 624 RFMVDIACGMEYLSSRN--FIHRDLAARNCMLAEDMTVCVADFGLSRKIYSGDYYRQGCA 681 Query: 505 VAGTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRR 329 +W+A E L DV++FGV +WE++T Q P+ G+ A++ + NR Sbjct: 682 SKLPVKWLALESLADNLYTVHSDVWAFGVTMWEIMTRGQTPYAGIENAEIYNYLIGGNR- 740 Query: 328 LPIPKDTIPELAALVESCWADDPRQRPSFSSI 233 L P + + E+ L+ CW+ DP+QRPSF+ + Sbjct: 741 LKQPPECMEEVYDLMYQCWSADPKQRPSFTCL 772
>VGFR3_HUMAN (P35916) Vascular endothelial growth factor receptor 3 precursor (EC| 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4) Length = 1298 Score = 82.4 bits (202), Expect = 1e-15 Identities = 46/152 (30%), Positives = 84/152 (55%), Gaps = 3/152 (1%) Frame = -1 Query: 673 ALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSR--FKATTFISSKSVA 500 + VA+G+ +L + +H DL N+L+ ++ VK+ DFGL+R +K ++ S Sbjct: 1018 SFQVARGMEFL--ASRKCIHRDLAARNILLSESDVVKICDFGLARDIYKDPDYVRKGSAR 1075 Query: 499 GTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRLP 323 +WMAPE + + + DV+SFGV+LWE+ ++ P+ G+ + R+ Sbjct: 1076 LPLKWMAPESIFDKVYTTQSDVWSFGVLLWEIFSLGASPYPGVQINEEFCQRLRDGTRMR 1135 Query: 322 IPKDTIPELAALVESCWADDPRQRPSFSSIVD 227 P+ P + ++ +CW+ DP+ RP+FS +V+ Sbjct: 1136 APELATPAIRRIMLNCWSGDPKARPAFSELVE 1167
>FGFR2_MOUSE (P21803) Fibroblast growth factor receptor 2 precursor (EC 2.7.10.1)| (FGFR-2) (Keratinocyte growth factor receptor) Length = 821 Score = 82.4 bits (202), Expect = 1e-15 Identities = 49/149 (32%), Positives = 80/149 (53%), Gaps = 3/149 (2%) Frame = -1 Query: 664 VAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAGT--P 491 +A+G+ YL + +H DL N+LV +N +K+ DFGL+R K+ G Sbjct: 610 LARGMEYL--ASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPV 667 Query: 490 EWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRLPIPK 314 +WMAPE L + DV+SFGV++WE+ T+ P+ G+ P + + + + R+ P Sbjct: 668 KWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGI-PVEELFKLLKEGHRMDKPT 726 Query: 313 DTIPELAALVESCWADDPRQRPSFSSIVD 227 + EL ++ CW P QRP+F +V+ Sbjct: 727 NCTNELYMMMRDCWHAVPSQRPTFKQLVE 755
>FGFR2_HUMAN (P21802) Fibroblast growth factor receptor 2 precursor (EC 2.7.10.1)| (FGFR-2) (Keratinocyte growth factor receptor 2) (CD332 antigen) Length = 821 Score = 82.4 bits (202), Expect = 1e-15 Identities = 49/149 (32%), Positives = 80/149 (53%), Gaps = 3/149 (2%) Frame = -1 Query: 664 VAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAGT--P 491 +A+G+ YL + +H DL N+LV +N +K+ DFGL+R K+ G Sbjct: 610 LARGMEYL--ASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPV 667 Query: 490 EWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRLPIPK 314 +WMAPE L + DV+SFGV++WE+ T+ P+ G+ P + + + + R+ P Sbjct: 668 KWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGI-PVEELFKLLKEGHRMDKPA 726 Query: 313 DTIPELAALVESCWADDPRQRPSFSSIVD 227 + EL ++ CW P QRP+F +V+ Sbjct: 727 NCTNELYMMMRDCWHAVPSQRPTFKQLVE 755
>NTRK3_PANTR (Q5IS37) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) Length = 825 Score = 82.4 bits (202), Expect = 1e-15 Identities = 55/151 (36%), Positives = 78/151 (51%), Gaps = 3/151 (1%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSR-FKATTFISSKSVA 500 +A +A G+ YL + VH DL T N LV N VK+GDFG+SR +T + Sbjct: 659 IASQIASGMVYL--ASQHFVHRDLATRNCLVGANLLVKIGDFGMSRDVYSTDYYRVGGHT 716 Query: 499 GTP-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRL 326 P WM PE + + DV+SFGVILWE+ T +QPW L +V+ + Q R L Sbjct: 717 MLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGKQPWFQLSNTEVIECIT-QGRVL 775 Query: 325 PIPKDTIPELAALVESCWADDPRQRPSFSSI 233 P+ E+ ++ CW +P+QR + I Sbjct: 776 ERPRVCPKEVYDVMLGCWQREPQQRLNIKEI 806
>NTRK3_MACFA (Q5IFJ9) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) Length = 825 Score = 82.4 bits (202), Expect = 1e-15 Identities = 55/151 (36%), Positives = 78/151 (51%), Gaps = 3/151 (1%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSR-FKATTFISSKSVA 500 +A +A G+ YL + VH DL T N LV N VK+GDFG+SR +T + Sbjct: 659 IASQIASGMVYL--ASQHFVHRDLATRNCLVGANLLVKIGDFGMSRDVYSTDYYRVGGHT 716 Query: 499 GTP-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRL 326 P WM PE + + DV+SFGVILWE+ T +QPW L +V+ + Q R L Sbjct: 717 MLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGKQPWFQLSNTEVIECIT-QGRVL 775 Query: 325 PIPKDTIPELAALVESCWADDPRQRPSFSSI 233 P+ E+ ++ CW +P+QR + I Sbjct: 776 ERPRVCPKEVYDVMLGCWQREPQQRLNIKEI 806
>FGFR1_MOUSE (P16092) Basic fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) (FGFR-1) (bFGF-R) (MFR) Length = 822 Score = 82.4 bits (202), Expect = 1e-15 Identities = 51/152 (33%), Positives = 81/152 (53%), Gaps = 3/152 (1%) Frame = -1 Query: 673 ALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAGT 494 A VA+G+ YL + +H DL N+LV ++ +K+ DFGL+R K+ G Sbjct: 604 AYQVARGMEYL--ASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGR 661 Query: 493 --PEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRLP 323 +WMAPE L + DV+SFGV+LWE+ T+ P+ G+ P + + + + R+ Sbjct: 662 LPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGV-PVEELFKLLKEGHRMD 720 Query: 322 IPKDTIPELAALVESCWADDPRQRPSFSSIVD 227 P + EL ++ CW P QRP+F +V+ Sbjct: 721 KPSNCTNELYMMMRDCWHAVPSQRPTFKQLVE 752
>FGFR1_HUMAN (P11362) Basic fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) (FGFR-1) (bFGF-R) (Fms-like tyrosine kinase 2) (c-fgr) (CD331 antigen) Length = 822 Score = 82.4 bits (202), Expect = 1e-15 Identities = 51/152 (33%), Positives = 81/152 (53%), Gaps = 3/152 (1%) Frame = -1 Query: 673 ALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAGT 494 A VA+G+ YL + +H DL N+LV ++ +K+ DFGL+R K+ G Sbjct: 604 AYQVARGMEYL--ASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGR 661 Query: 493 --PEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRLP 323 +WMAPE L + DV+SFGV+LWE+ T+ P+ G+ P + + + + R+ Sbjct: 662 LPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGV-PVEELFKLLKEGHRMD 720 Query: 322 IPKDTIPELAALVESCWADDPRQRPSFSSIVD 227 P + EL ++ CW P QRP+F +V+ Sbjct: 721 KPSNCTNELYMMMRDCWHAVPSQRPTFKQLVE 752
>7LESS_DROME (P13368) Protein sevenless (EC 2.7.10.1)| Length = 2554 Score = 82.4 bits (202), Expect = 1e-15 Identities = 57/161 (35%), Positives = 83/161 (51%), Gaps = 10/161 (6%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLV-------DKNWSVKVGDFGLSR--FKATT 524 M +DVA G +YL + VH DL N LV D+ +VK+GDFGL+R +K+ Sbjct: 2323 MCIDVANGCSYLEDMH--FVHRDLACRNCLVTESTGSTDRRRTVKIGDFGLARDIYKSDY 2380 Query: 523 FISSKSVAGTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAV 347 + WM+PE L + DV++FGV+ WE+LT+ QQP+ +V+ V Sbjct: 2381 YRKEGEGLLPVRWMSPESLVDGLFTTQSDVWAFGVLCWEILTLGQQPYAARNNFEVLAHV 2440 Query: 346 AFQNRRLPIPKDTIPELAALVESCWADDPRQRPSFSSIVDT 224 + RL P +L +L+ CW DP +RPSF +T Sbjct: 2441 K-EGGRLQQPPMCTEKLYSLLLLCWRTDPWERPSFRRCYNT 2480
>ILK1_HUMAN (Q13418) Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59| kDa serine/threonine-protein kinase) (p59ILK) Length = 452 Score = 82.4 bits (202), Expect = 1e-15 Identities = 46/153 (30%), Positives = 83/153 (54%), Gaps = 3/153 (1%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVA 500 + ALD+A+G+ +LH P I L + ++++D++ + ++ ++ K + + A Sbjct: 296 KFALDMARGMAFLHTLEPLIPRHALNSRSVMIDEDMTARIS---MADVKFSFQCPGRMYA 352 Query: 499 GTPEWMAPEFLRGEPSN---EKCDVYSFGVILWELLTMQQPWGGLGPAQVVGAVAFQNRR 329 P W+APE L+ +P + D++SF V+LWEL+T + P+ L ++ VA + R Sbjct: 353 --PAWVAPEALQKKPEDTNRRSADMWSFAVLLWELVTREVPFADLSNMEIGMKVALEGLR 410 Query: 328 LPIPKDTIPELAALVESCWADDPRQRPSFSSIV 230 IP P + L++ C +DP +RP F IV Sbjct: 411 PTIPPGISPHVCKLMKICMNEDPAKRPKFDMIV 443
>RIPK3_HUMAN (Q9Y572) Receptor-interacting serine/threonine-protein kinase 3 (EC| 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) Length = 518 Score = 82.4 bits (202), Expect = 1e-15 Identities = 54/158 (34%), Positives = 81/158 (51%), Gaps = 12/158 (7%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFK--ATTFISSKS 506 R+ +V G+ YLH NP ++H DLK N+L D VK+ DFGLS F+ + + S Sbjct: 119 RLLKEVVLGMFYLHDQNPVLLHRDLKPSNVLPDPELHVKLADFGLSTFQGGSQSGTGSGE 178 Query: 505 VAGTPEWMAPEFL--RGEPSNEKCDVYSFGVILWELLTMQQPWGGLGPAQVVGAVAFQNR 332 GT ++APE ++ DVYSFG+++W +L ++ P+ V AV + Sbjct: 179 PGGTLGYLAPELFVNVNRKASTASDVYSFGILMWAVLAGREVELPTEPSLVYEAVCNRQN 238 Query: 331 R-----LPIPKDTIPELAA---LVESCWADDPRQRPSF 242 R LP P L L++ CW+ +P+ RPSF Sbjct: 239 RPSLAELPQAGPETPGLEGLKELMQLCWSSEPKDRPSF 276
>PTK6_HUMAN (Q13882) Tyrosine-protein kinase 6 (EC 2.7.10.2) (Breast tumor| kinase) (Tyrosine-protein kinase BRK) Length = 451 Score = 82.4 bits (202), Expect = 1e-15 Identities = 53/149 (35%), Positives = 77/149 (51%), Gaps = 1/149 (0%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAG 497 +A VA+G+ YL N +H DL N+LV +N KVGDFGL+R S Sbjct: 292 IAWQVAEGMCYLESQN--YIHRDLAARNILVGENTLCKVGDFGLARLIKEDVYLSHDHNI 349 Query: 496 TPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQ-PWGGLGPAQVVGAVAFQNRRLPI 320 +W APE L + K DV+SFG++L E+ + Q P+ G+ + V R+P Sbjct: 350 PYKWTAPEALSRGHYSTKSDVWSFGILLHEMFSRGQVPYPGMSNHEAFLRVD-AGYRMPC 408 Query: 319 PKDTIPELAALVESCWADDPRQRPSFSSI 233 P + P + L+ +CW DP QRP F ++ Sbjct: 409 PLECPPSVHKLMLTCWCRDPEQRPCFKAL 437
>MATK_MOUSE (P41242) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK) Length = 505 Score = 82.4 bits (202), Expect = 1e-15 Identities = 53/152 (34%), Positives = 83/152 (54%), Gaps = 1/152 (0%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVA 500 + AL VA+G+ YL + +VH DL N+LV ++ KV DFGL++ + SS+ Sbjct: 329 QFALHVAEGMEYLE--SKKLVHRDLAARNILVSEDLVAKVSDFGLAKAERKGLDSSRLPV 386 Query: 499 GTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRLP 323 +W APE L+ + K DV+SFGV+LWE+ + + P+ + +V AV + R+ Sbjct: 387 ---KWTAPEALKNGRFSSKSDVWSFGVLLWEVFSYGRAPYPKMSLKEVSEAVE-KGYRME 442 Query: 322 IPKDTIPELAALVESCWADDPRQRPSFSSIVD 227 P + L+ SCW +P +RP F IV+ Sbjct: 443 PPDGCPGSVHTLMGSCWEAEPARRPPFRKIVE 474
>TYRO3_HUMAN (Q06418) Tyrosine-protein kinase receptor TYRO3 precursor (EC| 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine-protein kinase DTK) (Protein-tyrosine kinase byk) Length = 890 Score = 82.0 bits (201), Expect = 1e-15 Identities = 49/152 (32%), Positives = 83/152 (54%), Gaps = 3/152 (1%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSR--FKATTFISSKS 506 R +D+A G+ YL N +H DL N ++ ++ +V V DFGLSR + + + Sbjct: 634 RFMVDIACGMEYLSSRN--FIHRDLAARNCMLAEDMTVCVADFGLSRKIYSGDYYRQGCA 691 Query: 505 VAGTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRR 329 +W+A E L + DV++FGV +WE++T Q P+ G+ A++ + NR Sbjct: 692 SKLPVKWLALESLADNLYTVQSDVWAFGVTMWEIMTRGQTPYAGIENAEIYNYLIGGNR- 750 Query: 328 LPIPKDTIPELAALVESCWADDPRQRPSFSSI 233 L P + + ++ L+ CW+ DP+QRPSF+ + Sbjct: 751 LKQPPECMEDVYDLMYQCWSADPKQRPSFTCL 782
>ILK_MOUSE (O55222) Integrin-linked protein kinase (EC 2.7.11.1)| Length = 452 Score = 82.0 bits (201), Expect = 1e-15 Identities = 45/153 (29%), Positives = 83/153 (54%), Gaps = 3/153 (1%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVA 500 + ALD+A+G+ +LH P I L + ++++D++ + ++ ++ K + + A Sbjct: 296 KFALDMARGMAFLHTLEPLIPRHALNSRSVMIDEDMTARIS---MADVKFSFQCPGRMYA 352 Query: 499 GTPEWMAPEFLRGEPSN---EKCDVYSFGVILWELLTMQQPWGGLGPAQVVGAVAFQNRR 329 P W+APE L+ +P + D++SF V+LWEL+T + P+ L ++ VA + R Sbjct: 353 --PAWVAPEALQKKPEDTNRRSADMWSFAVLLWELVTREVPFADLSNMEIGMKVALEGLR 410 Query: 328 LPIPKDTIPELAALVESCWADDPRQRPSFSSIV 230 +P P + L++ C +DP +RP F IV Sbjct: 411 PTVPPGISPHVCKLMKICMNEDPAKRPKFDMIV 443
>BRI1_ARATH (O22476) BRASSINOSTEROID INSENSITIVE 1 precursor (EC 2.7.11.1)| (AtBRI1) (Brassinosteroid LRR receptor kinase) Length = 1196 Score = 82.0 bits (201), Expect = 1e-15 Identities = 50/133 (37%), Positives = 82/133 (61%), Gaps = 5/133 (3%) Frame = -1 Query: 679 RMALDVAKGINYLHCX-NPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKAT--TFISSK 509 ++A+ A+G+ +LH +P I+H D+K+ N+L+D+N +V DFG++R + T +S Sbjct: 985 KIAIGSARGLAFLHHNCSPHIIHRDMKSSNVLLDENLEARVSDFGMARLMSAMDTHLSVS 1044 Query: 508 SVAGTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQPWGG--LGPAQVVGAVAFQN 335 ++AGTP ++ PE+ + + K DVYS+GV+L ELLT ++P G +VG V Q+ Sbjct: 1045 TLAGTPGYVPPEYYQSFRCSTKGDVYSYGVVLLELLTGKRPTDSPDFGDNNLVGWVK-QH 1103 Query: 334 RRLPIPKDTIPEL 296 +L I PEL Sbjct: 1104 AKLRISDVFDPEL 1116
>EPB1A_XENLA (Q91571) Ephrin type-B receptor 1-A precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor XEK) Length = 985 Score = 82.0 bits (201), Expect = 1e-15 Identities = 53/157 (33%), Positives = 78/157 (49%), Gaps = 6/157 (3%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRF-----KATTFISS 512 M +A G+ YL N VH DL N+LV+ N KV DFGLSR+ T+ SS Sbjct: 725 MLRGIAAGMKYLSEMN--YVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSS 782 Query: 511 KSVAGTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQN 335 W A E + DV+S+G+++WE+++ ++P+ + V+ A+ Q+ Sbjct: 783 LGGKIPVRWTAQEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWTMSNQDVINAIE-QD 841 Query: 334 RRLPIPKDTIPELAALVESCWADDPRQRPSFSSIVDT 224 RLP P D L L+ CW D RP + IV+T Sbjct: 842 YRLPPPMDCPAALHQLMLDCWQKDRNSRPRLAEIVNT 878
>MATK_RAT (P41243) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase BATK) Length = 467 Score = 82.0 bits (201), Expect = 1e-15 Identities = 52/152 (34%), Positives = 83/152 (54%), Gaps = 1/152 (0%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVA 500 + AL VA+G+ YL + +VH DL N+LV ++ KV DFGL++ + + S + Sbjct: 290 QFALHVAEGMEYLE--SKKLVHRDLAARNILVSEDLVAKVSDFGLAKAELRKGLDSSRLP 347 Query: 499 GTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRLP 323 +W APE L+ + K DV+SFGV+LWE+ + + P+ + +V AV + R+ Sbjct: 348 --VKWTAPEALKNGRFSSKSDVWSFGVLLWEVFSYGRAPYPKMSLKEVSEAVE-KGYRME 404 Query: 322 IPKDTIPELAALVESCWADDPRQRPSFSSIVD 227 P + L+ SCW +P +RP F IV+ Sbjct: 405 PPDSCPGPVHTLMGSCWEAEPSRRPPFRKIVE 436
>SRMS_MOUSE (Q62270) Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70)| Length = 496 Score = 82.0 bits (201), Expect = 1e-15 Identities = 51/147 (34%), Positives = 80/147 (54%), Gaps = 2/147 (1%) Frame = -1 Query: 673 ALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAGT 494 A VA+G++YL +VH DL N+LV + + KV DFGL+R S S + Sbjct: 335 ACQVAEGMSYLE--ERRVVHRDLAARNVLVGDDLTCKVADFGLARLLKDDVYSPSSGSKI 392 Query: 493 P-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQ-PWGGLGPAQVVGAVAFQNRRLPI 320 P +W APE ++K DV+SFG++L+E+ T Q P+ G+ + + ++ + RLP Sbjct: 393 PVKWTAPEAANYRVFSQKSDVWSFGILLYEVFTYGQCPYEGMTNHETLQQIS-RGYRLPR 451 Query: 319 PKDTIPELAALVESCWADDPRQRPSFS 239 P E+ L+ CW P +RP+F+ Sbjct: 452 PAVCPAEVYVLMVECWKGSPEERPTFA 478
>KRAF1_CAEEL (Q07292) Raf homolog serine/threonine-protein kinase (EC 2.7.11.1)| (Abnormal cell lineage protein 45) Length = 813 Score = 82.0 bits (201), Expect = 1e-15 Identities = 53/158 (33%), Positives = 84/158 (53%), Gaps = 12/158 (7%) Frame = -1 Query: 664 VAKGINYLHCXNPPIVHWDLKTPNM-LVDKNWSVKVGDFGLSRFKATTFISS----KSVA 500 V+ G+NYLH N I+H DLKT N+ L+D +VK+GDFGL+ K ++ + Sbjct: 586 VSLGMNYLHSKN--IIHRDLKTNNIFLMDDMSTVKIGDFGLATVKTKWTVNGGQQQQQPT 643 Query: 499 GTPEWMAPEFLRGEPSNE---KCDVYSFGVILWELLTMQQPWGGLGPAQ----VVGAVAF 341 G+ WMAPE +R + N + DVYSFG+ ++E+L+ P+ + +VG Sbjct: 644 GSILWMAPEVIRMQDDNPYTPQSDVYSFGICMYEILSSHLPYSNINNRDQILFMVGRGYL 703 Query: 340 QNRRLPIPKDTIPELAALVESCWADDPRQRPSFSSIVD 227 + R I DT + L ++C D +RP F +++ Sbjct: 704 RPDRSKIRHDTPKSMLKLYDNCIMFDRNERPVFGEVLE 741
>TIE2_BRARE (O73791) Tyrosine-protein kinase receptor Tie-2 precursor (EC| 2.7.10.1) Length = 1116 Score = 81.6 bits (200), Expect = 2e-15 Identities = 52/148 (35%), Positives = 81/148 (54%), Gaps = 2/148 (1%) Frame = -1 Query: 667 DVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAGTP- 491 DVA+G++YL +H DL N+LV +N+ K+ DFGLSR K++ P Sbjct: 939 DVARGMSYL--SQKQFIHRDLAARNVLVGENFVAKIADFGLSR--GQEVYVKKTMGRLPV 994 Query: 490 EWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRLPIPK 314 WMA E L DV+S+GV+LWE++++ P+ G+ A++ + RL P Sbjct: 995 RWMAIESLNYSVYTTNSDVWSYGVLLWEVVSLGGTPYCGMTCAELYEKLPL-GFRLEKPL 1053 Query: 313 DTIPELAALVESCWADDPRQRPSFSSIV 230 + E+ L++ CW + P +RPSFS I+ Sbjct: 1054 NCDDEVYELMQQCWREKPFERPSFSQIL 1081
>BRI1_LYCPE (Q8L899) Systemin receptor SR160 precursor (EC 2.7.11.1)| (Brassinosteroid LRR receptor kinase) Length = 1207 Score = 81.6 bits (200), Expect = 2e-15 Identities = 42/102 (41%), Positives = 69/102 (67%), Gaps = 4/102 (3%) Frame = -1 Query: 679 RMALDVAKGINYLH--CXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKAT--TFISS 512 ++A+ A+G+ +LH C P I+H D+K+ N+L+D+N +V DFG++R + T +S Sbjct: 990 KIAIGAARGLAFLHHNCI-PHIIHRDMKSSNVLLDENLEARVSDFGMARLMSAMDTHLSV 1048 Query: 511 KSVAGTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQP 386 ++AGTP ++ PE+ + + K DVYS+GV+L ELLT +QP Sbjct: 1049 STLAGTPGYVPPEYYQSFRCSTKGDVYSYGVVLLELLTGKQP 1090
>BRI1_LYCES (Q8GUQ5) Brassinosteroid LRR receptor kinase precursor (EC 2.7.11.1)| (tBRI1) (Altered brassinolide sensitivity 1) (Systemin receptor SR160) Length = 1207 Score = 81.6 bits (200), Expect = 2e-15 Identities = 42/102 (41%), Positives = 69/102 (67%), Gaps = 4/102 (3%) Frame = -1 Query: 679 RMALDVAKGINYLH--CXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKAT--TFISS 512 ++A+ A+G+ +LH C P I+H D+K+ N+L+D+N +V DFG++R + T +S Sbjct: 990 KIAIGAARGLAFLHHNCI-PHIIHRDMKSSNVLLDENLEARVSDFGMARLMSAMDTHLSV 1048 Query: 511 KSVAGTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQP 386 ++AGTP ++ PE+ + + K DVYS+GV+L ELLT +QP Sbjct: 1049 STLAGTPGYVPPEYYQSFRCSTKGDVYSYGVVLLELLTGKQP 1090
>FES_FSVGA (P00542) Tyrosine-protein kinase transforming protein Fes (EC| 2.7.10.2) Length = 609 Score = 81.6 bits (200), Expect = 2e-15 Identities = 55/152 (36%), Positives = 81/152 (53%), Gaps = 3/152 (1%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKAT-TFISSKSV 503 +M D A G+ YL + +H DL N LV + +K+ DFG+SR A + +S + Sbjct: 449 QMVGDAAAGMEYLE--SKCCIHRDLAARNCLVTEKNVLKISDFGMSREAADGIYAASGGL 506 Query: 502 AGTP-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRR 329 P +W APE L + + DV+SFG++LWE ++ P+ L Q V + R Sbjct: 507 RQVPVKWTAPEALNYGRYSSESDVWSFGILLWETFSLGASPYPNLSNQQTREFVE-KGGR 565 Query: 328 LPIPKDTIPELAALVESCWADDPRQRPSFSSI 233 LP P+ + L+E CWA +P QRPSFS+I Sbjct: 566 LPCPELCPDAVFRLMEQCWAYEPGQRPSFSAI 597
>ROR1_MOUSE (Q9Z139) Tyrosine-protein kinase transmembrane receptor ROR1| precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1) (mROR1) Length = 937 Score = 81.6 bits (200), Expect = 2e-15 Identities = 49/151 (32%), Positives = 80/151 (52%), Gaps = 3/151 (1%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSR-FKATTFISSKSVA 500 +A+ +A G+ YL + VH DL N+L+ + VK+ D GLSR + + +S + Sbjct: 595 IAIQIAAGMEYL--SSHFFVHKDLAARNILIGEQLHVKISDLGLSREIYSADYYRVQSKS 652 Query: 499 GTP-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRL 326 P WM PE + + D++SFGV+LWE+ + QP+ G +V+ V + + L Sbjct: 653 SLPIRWMPPEAIMYGKFSSDSDIWSFGVVLWEIFSFGLQPYYGFSNQEVIEMVR-KRQLL 711 Query: 325 PIPKDTIPELAALVESCWADDPRQRPSFSSI 233 P +D P + +L+ CW + P +RP F I Sbjct: 712 PCSEDCPPRMYSLMTECWNEIPSRRPRFKDI 742
>ROR1_HUMAN (Q01973) Tyrosine-protein kinase transmembrane receptor ROR1| precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1) Length = 937 Score = 81.6 bits (200), Expect = 2e-15 Identities = 51/152 (33%), Positives = 82/152 (53%), Gaps = 4/152 (2%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSR--FKATTF-ISSKS 506 +A+ +A G+ YL + VH DL N+L+ + VK+ D GLSR + A + + SKS Sbjct: 595 IAIQIAAGMEYL--SSHFFVHKDLAARNILIGEQLHVKISDLGLSREIYSADYYRVQSKS 652 Query: 505 VAGTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRR 329 + WM PE + + D++SFGV+LWE+ + QP+ G +V+ V + + Sbjct: 653 LLPI-RWMPPEAIMYGKFSSDSDIWSFGVVLWEIFSFGLQPYYGFSNQEVIEMVR-KRQL 710 Query: 328 LPIPKDTIPELAALVESCWADDPRQRPSFSSI 233 LP +D P + +L+ CW + P +RP F I Sbjct: 711 LPCSEDCPPRMYSLMTECWNEIPSRRPRFKDI 742
>VGFR2_HUMAN (P35968) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Kinase insert domain receptor) (Protein-tyrosine kinase receptor Flk-1) (CD309 antigen) Length = 1356 Score = 81.6 bits (200), Expect = 2e-15 Identities = 48/152 (31%), Positives = 80/152 (52%), Gaps = 3/152 (1%) Frame = -1 Query: 673 ALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSR--FKATTFISSKSVA 500 + VAKG+ +L + +H DL N+L+ + VK+ DFGL+R +K ++ Sbjct: 1009 SFQVAKGMEFL--ASRKCIHRDLAARNILLSEKNVVKICDFGLARDIYKDPDYVRKGDAR 1066 Query: 499 GTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRLP 323 +WMAPE + + DV+SFGV+LWE+ ++ P+ G+ + + R+ Sbjct: 1067 LPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMR 1126 Query: 322 IPKDTIPELAALVESCWADDPRQRPSFSSIVD 227 P T PE+ + CW +P QRP+FS +V+ Sbjct: 1127 APDYTTPEMYQTMLDCWHGEPSQRPTFSELVE 1158
>ABL_FSVHY (P10447) Tyrosine-protein kinase transforming protein Abl (EC| 2.7.10.2) (V-abl) Length = 439 Score = 81.6 bits (200), Expect = 2e-15 Identities = 51/150 (34%), Positives = 79/150 (52%), Gaps = 2/150 (1%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKA-TTFISSKSVA 500 MA ++ + YL N +H DL N LV +N VKV DFGLSR T+ + Sbjct: 292 MATQISSAMEYLEKKN--FIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGTK 349 Query: 499 GTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRLP 323 +W APE L + K DV++FGV+LWE+ T P+ G+ +QV + ++ R+ Sbjct: 350 FPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLE-KDYRME 408 Query: 322 IPKDTIPELAALVESCWADDPRQRPSFSSI 233 P+ ++ L+ +CW +P RP+F+ I Sbjct: 409 RPEGCPEKVYELMRACWQWNPSDRPAFAEI 438
>KRAF1_DROME (P11346) Raf homolog serine/threonine-protein kinase dRAF-1 (EC| 2.7.11.1) (Protein pole-hole) Length = 739 Score = 81.6 bits (200), Expect = 2e-15 Identities = 53/156 (33%), Positives = 84/156 (53%), Gaps = 10/156 (6%) Frame = -1 Query: 664 VAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSV---AGT 494 VA+G++YLH N I+H DLK+ N+ + ++ SVK+GDFGL+ K T + K G+ Sbjct: 532 VAQGMDYLHAKN--IIHRDLKSNNIFLHEDLSVKIGDFGLATAK-TRWSGEKQANQPTGS 588 Query: 493 PEWMAPEFLRGE---PSNEKCDVYSFGVILWELLTMQQPWGGLGPAQ----VVGAVAFQN 335 WMAPE +R + P + + DVY+FG++++ELL P+G + +VG + Sbjct: 589 ILWMAPEVIRMQELNPYSFQSDVYAFGIVMYELLAECLPYGHISNKDQILFMVGRGLLRP 648 Query: 334 RRLPIPKDTIPELAALVESCWADDPRQRPSFSSIVD 227 + D L L E C P+ RP F +++ Sbjct: 649 DMSQVRSDAPQALKRLAEDCIKYTPKDRPLFRPLLN 684
>XMRK_XIPMA (P13388) Melanoma receptor tyrosine-protein kinase precursor (EC| 2.7.10.1) Length = 1167 Score = 81.6 bits (200), Expect = 2e-15 Identities = 51/150 (34%), Positives = 79/150 (52%), Gaps = 3/150 (2%) Frame = -1 Query: 670 LDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAGTP 491 + +AKG+NYL + +VH DL N+L+ VK+ DFGLS+ ++ G Sbjct: 817 VQIAKGMNYLEERH--LVHRDLAARNVLLKNPNHVKITDFGLSKLLTADEKEYQADGGKV 874 Query: 490 --EWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRLPI 320 +WMA E + + DV+S+GV +WEL+T +P+ G+ PA+ + +V RLP Sbjct: 875 PIKWMALESILQWTYTHQSDVWSYGVTVWELMTFGSKPYDGI-PAKEIASVLENGERLPQ 933 Query: 319 PKDTIPELAALVESCWADDPRQRPSFSSIV 230 P E+ ++ CW DP RP F +V Sbjct: 934 PPICTIEVYMIILKCWMIDPSSRPRFRELV 963
>EPHA2_HUMAN (P29317) Ephrin type-A receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) Length = 976 Score = 81.6 bits (200), Expect = 2e-15 Identities = 52/153 (33%), Positives = 78/153 (50%), Gaps = 4/153 (2%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAG 497 M +A G+ YL N VH DL N+LV+ N KV DFGLSR ++ + +G Sbjct: 719 MLRGIAAGMKYL--ANMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEATYTTSG 776 Query: 496 TP---EWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRR 329 W APE + DV+SFG+++WE++T ++P+ L +V+ A+ R Sbjct: 777 GKIPIRWTAPEAISYRKFTSASDVWSFGIVMWEVMTYGERPYWELSNHEVMKAIN-DGFR 835 Query: 328 LPIPKDTIPELAALVESCWADDPRQRPSFSSIV 230 LP P D + L+ CW + +RP F+ IV Sbjct: 836 LPTPMDCPSAIYQLMMQCWQQERARRPKFADIV 868
>MOS_CHICK (P10741) Serine/threonine-protein kinase mos (EC 2.7.11.1) (Oocyte| maturation factor mos) Length = 349 Score = 81.6 bits (200), Expect = 2e-15 Identities = 53/156 (33%), Positives = 80/156 (51%), Gaps = 10/156 (6%) Frame = -1 Query: 667 DVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVA---G 497 D+ G+ +LH IVH DLK N+L+ ++ + K+GDFG S+ S V G Sbjct: 188 DIVTGLAFLHSQG--IVHLDLKPANILITEHGACKIGDFGCSQRLEEGLSQSHHVCQQGG 245 Query: 496 TPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQPWGGLGPAQ-VVGAVAFQNRRLPI 320 T APE L+GE K D+YSF + LW+++ +QP+ LG Q V+ AV N R P+ Sbjct: 246 TYTHRAPELLKGERVTAKADIYSFAITLWQIVMREQPY--LGERQYVLYAVVAYNLRPPL 303 Query: 319 PKDTIPE------LAALVESCWADDPRQRPSFSSIV 230 E L +++ CW D +R S + ++ Sbjct: 304 AAAIFHESAVGQRLRSIISCCWKADVEERLSAAQLL 339
>RIPK1_HUMAN (Q13546) Receptor-interacting serine/threonine-protein kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein) Length = 671 Score = 81.6 bits (200), Expect = 2e-15 Identities = 53/169 (31%), Positives = 86/169 (50%), Gaps = 20/169 (11%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFI------ 518 R+ L++ +G+ YLH ++H DLK N+LVD ++ +K+ D GL+ FK + + Sbjct: 117 RIILEIIEGMCYLH--GKGVIHKDLKPENILVDNDFHIKIADLGLASFKMWSKLNNEEHN 174 Query: 517 -------SSKSVAGTPEWMAPEFLR--GEPSNEKCDVYSFGVILWELLTMQQPW-GGLGP 368 ++K GT +MAPE L EK DVYSF V+LW + ++P+ + Sbjct: 175 ELREVDGTAKKNGGTLYYMAPEHLNDVNAKPTEKSDVYSFAVVLWAIFANKEPYENAICE 234 Query: 367 AQVVGAVAFQNRRLPIPKDTIP----ELAALVESCWADDPRQRPSFSSI 233 Q++ + NR P D E+ +L++ CW +P RP+F I Sbjct: 235 QQLIMCIKSGNR--PDVDDITEYCPREIISLMKLCWEANPEARPTFPGI 281
>ROS_CHICK (P08941) Proto-oncogene tyrosine-protein kinase ROS precursor (EC| 2.7.10.1) (c-ros-1) Length = 2311 Score = 81.6 bits (200), Expect = 2e-15 Identities = 56/154 (36%), Positives = 78/154 (50%), Gaps = 9/154 (5%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLV-DKNWS-----VKVGDFGLSR--FKATTF 521 + LD+ KG YL +H DL N LV +K + VK+GDFGL+R +K + Sbjct: 2075 ICLDICKGCVYLEKMR--FIHRDLAARNCLVSEKQYGSCSRVVKIGDFGLARDIYKNDYY 2132 Query: 520 ISSKSVAGTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVA 344 WMAPE L DV++FGV++WE LT+ QQP+ GL +V+ V Sbjct: 2133 RKRGEGLINVRWMAPESLIDGVFTNHSDVWAFGVLVWETLTLGQQPYPGLSNIEVLHHVR 2192 Query: 343 FQNRRLPIPKDTIPELAALVESCWADDPRQRPSF 242 RL P + ++ L+ CWA DP RP+F Sbjct: 2193 -SGGRLESPNNCPDDIRDLMTRCWAQDPHNRPTF 2225
>FES_HUMAN (P07332) Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2)| (C-Fes) Length = 822 Score = 81.6 bits (200), Expect = 2e-15 Identities = 55/152 (36%), Positives = 81/152 (53%), Gaps = 3/152 (1%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKAT-TFISSKSV 503 +M D A G+ YL + +H DL N LV + +K+ DFG+SR +A + +S Sbjct: 662 QMVGDAAAGMEYLE--SKCCIHRDLAARNCLVTEKNVLKISDFGMSREEADGVYAASGGS 719 Query: 502 AGTP-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRR 329 P +W APE L + + DV+SFG++LWE ++ P+ L Q V + R Sbjct: 720 RQVPVKWTAPEALNYGRYSSESDVWSFGILLWETFSLGASPYPNLSNQQTREFVE-KGGR 778 Query: 328 LPIPKDTIPELAALVESCWADDPRQRPSFSSI 233 LP P+ + L+E CWA +P QRPSFS+I Sbjct: 779 LPCPELCPDAVFRLMEQCWAYEPGQRPSFSTI 810
>EPHA1_MOUSE (Q60750) Ephrin type-A receptor 1 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ESK) Length = 977 Score = 81.3 bits (199), Expect = 3e-15 Identities = 53/149 (35%), Positives = 78/149 (52%), Gaps = 4/149 (2%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAG 497 M L +A G+N L N VH DL N+LV++N KV DFGL+R F + G Sbjct: 730 MLLGIASGMNCLSGHN--YVHRDLAARNILVNQNLCCKVSDFGLTRL-LDDFDGTYETQG 786 Query: 496 TP---EWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRR 329 W APE + DV+SFG+++WE+L+ +P+G + +V+ ++ R Sbjct: 787 GKIPIRWTAPEAIAHRIFTTASDVWSFGIVMWEVLSFGDKPYGEMSNQEVMKSIE-DGYR 845 Query: 328 LPIPKDTIPELAALVESCWADDPRQRPSF 242 LP P D L L+++CWA D +RP F Sbjct: 846 LPPPVDCPAPLYELMKNCWAYDRARRPHF 874
>MOS_CERAE (P10650) Proto-oncogene serine/threonine-protein kinase mos (EC| 2.7.11.1) (c-mos) (Oocyte maturation factor mos) Length = 346 Score = 81.3 bits (199), Expect = 3e-15 Identities = 51/154 (33%), Positives = 78/154 (50%), Gaps = 9/154 (5%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKS-- 506 + +LDV G+ +LH + IVH DLK N+L+ + K+ DFG S K + ++ Sbjct: 180 KYSLDVVNGLLFLHSQS--IVHLDLKPANILISEQDVCKISDFGCSE-KLEDLLCFQTPL 236 Query: 505 --VAGTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQPWGGLGPAQVVGAVAFQNR 332 + GT APE L+GE K D+YSF + LW++ T Q P+ G + VA+ R Sbjct: 237 YPLGGTYTHRAPELLKGEGVTPKADIYSFAITLWQMTTKQAPYSGERQHILYAVVAYDLR 296 Query: 331 ---RLPIPKDTIP--ELAALVESCWADDPRQRPS 245 + +D++P L ++ CW QRPS Sbjct: 297 PSLSAAVFQDSLPGQRLGDVIRRCWRPSAAQRPS 330
>NEK8_HUMAN (Q86SG6) Serine/threonine-protein kinase Nek8 (EC 2.7.11.1) (Never| in mitosis A-related kinase 8) (NimA-related protein kinase 8) (NIMA-related kinase 12a) Length = 692 Score = 81.3 bits (199), Expect = 3e-15 Identities = 54/143 (37%), Positives = 83/143 (58%), Gaps = 6/143 (4%) Frame = -1 Query: 640 HCXNPPIVHWDLKTPNMLVDKN-WSVKVGDFGLSRFKATTFISSKS----VAGTPEWMAP 476 H I+H DLKT N+L+DK+ VK+GDFG+S+ +SSKS V GTP +++P Sbjct: 118 HVHTHLILHRDLKTQNILLDKHRMVVKIGDFGISKI-----LSSKSKAYTVVGTPCYISP 172 Query: 475 EFLRGEPSNEKCDVYSFGVILWELLTMQQPWGGLG-PAQVVGAVAFQNRRLPIPKDTIPE 299 E G+P N+K D+++ G +L+EL ++++ + PA V+ ++ PI PE Sbjct: 173 ELCEGKPYNQKSDIWALGCVLYELASLKRAFEAANLPALVLKIMS--GTFAPISDRYSPE 230 Query: 298 LAALVESCWADDPRQRPSFSSIV 230 L LV S + +P QRP S I+ Sbjct: 231 LRQLVLSLLSLEPAQRPPLSHIM 253
>FYN_HUMAN (P06241) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) (Protooncogene Syn) (SLK) Length = 536 Score = 81.3 bits (199), Expect = 3e-15 Identities = 52/147 (35%), Positives = 79/147 (53%), Gaps = 2/147 (1%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAG 497 MA VA G+ Y+ N +H DL++ N+LV K+ DFGL+R +++ A Sbjct: 369 MAAQVAAGMAYIERMN--YIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAK 426 Query: 496 TP-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQ-PWGGLGPAQVVGAVAFQNRRLP 323 P +W APE K DV+SFG++L EL+T + P+ G+ +V+ V + R+P Sbjct: 427 FPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVE-RGYRMP 485 Query: 322 IPKDTIPELAALVESCWADDPRQRPSF 242 P+D L L+ CW DP +RP+F Sbjct: 486 CPQDCPISLHELMIHCWKKDPEERPTF 512
>FYN_MOUSE (P39688) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 533 Score = 81.3 bits (199), Expect = 3e-15 Identities = 52/147 (35%), Positives = 79/147 (53%), Gaps = 2/147 (1%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAG 497 MA VA G+ Y+ N +H DL++ N+LV K+ DFGL+R +++ A Sbjct: 366 MAAQVAAGMAYIERMN--YIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAK 423 Query: 496 TP-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQ-PWGGLGPAQVVGAVAFQNRRLP 323 P +W APE K DV+SFG++L EL+T + P+ G+ +V+ V + R+P Sbjct: 424 FPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVE-RGYRMP 482 Query: 322 IPKDTIPELAALVESCWADDPRQRPSF 242 P+D L L+ CW DP +RP+F Sbjct: 483 CPQDCPISLHELMIHCWKKDPEERPTF 509
>FYN_CHICK (Q05876) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 533 Score = 81.3 bits (199), Expect = 3e-15 Identities = 52/147 (35%), Positives = 79/147 (53%), Gaps = 2/147 (1%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAG 497 MA VA G+ Y+ N +H DL++ N+LV K+ DFGL+R +++ A Sbjct: 366 MAAQVAAGMAYIERMN--YIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAK 423 Query: 496 TP-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQ-PWGGLGPAQVVGAVAFQNRRLP 323 P +W APE K DV+SFG++L EL+T + P+ G+ +V+ V + R+P Sbjct: 424 FPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVE-RGYRMP 482 Query: 322 IPKDTIPELAALVESCWADDPRQRPSF 242 P+D L L+ CW DP +RP+F Sbjct: 483 CPQDCPISLHELMIHCWKKDPEERPTF 509
>PKPA_PHYBL (Q01577) Serine/threonine-protein kinase pkpA (EC 2.7.11.1)| Length = 613 Score = 81.3 bits (199), Expect = 3e-15 Identities = 49/137 (35%), Positives = 72/137 (52%), Gaps = 2/137 (1%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLVD-KNWSVKVGDFGLSRFKATTFISSKSV 503 R + KG+ YLH PPI+H D+K N+ ++ + +K+GD G + K +V Sbjct: 117 RWCRQILKGLAYLHGHEPPIIHRDIKCDNIFINGAHGEIKIGDMGTAEMKNG---KKYTV 173 Query: 502 AGTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQPWGGLGPA-QVVGAVAFQNRRL 326 GTPE+MAPE + NEK D+Y+FG+ L E+ T + P+G A QV V + Sbjct: 174 IGTPEFMAPEMYEEQGYNEKVDIYAFGMCLLEMATGEYPYGECTNAVQVFKKVTQTIKPE 233 Query: 325 PIPKDTIPELAALVESC 275 + + PEL LV C Sbjct: 234 CLSRVQDPELLTLVNIC 250
>NTRK2_MOUSE (P15209) BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB/GP95-TrkB) (Trk-B) Length = 821 Score = 81.3 bits (199), Expect = 3e-15 Identities = 54/151 (35%), Positives = 77/151 (50%), Gaps = 3/151 (1%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSR-FKATTFISSKSVA 500 +A +A G+ YL + VH DL T N LV +N VK+GDFG+SR +T + Sbjct: 655 IAQQIAAGMVYL--ASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYSTDYYRVGGHT 712 Query: 499 GTP-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRL 326 P WM PE + + DV+S GV+LWE+ T +QPW L +V+ + Q R L Sbjct: 713 MLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECIT-QGRVL 771 Query: 325 PIPKDTIPELAALVESCWADDPRQRPSFSSI 233 P+ E+ L+ CW +P R + SI Sbjct: 772 QRPRTCPQEVYELMLGCWQREPHTRKNIKSI 802
>MUSK_RAT (Q62838) Muscle, skeletal receptor tyrosine protein kinase precursor| (EC 2.7.10.1) (Muscle-specific kinase receptor) (MuSK) Length = 868 Score = 81.3 bits (199), Expect = 3e-15 Identities = 56/151 (37%), Positives = 80/151 (52%), Gaps = 3/151 (1%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSR--FKATTFISSKSV 503 +A VA G+ YL VH DL T N LV +N VK+ DFGLSR + A + + + Sbjct: 704 IARQVAAGMAYL--SERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYSADYYKADGND 761 Query: 502 AGTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRL 326 A WM PE + + DV+++GV+LWE+ + QP+ G+ +V+ V N L Sbjct: 762 AIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGN-IL 820 Query: 325 PIPKDTIPELAALVESCWADDPRQRPSFSSI 233 P++ EL L+ CW+ P RPSF SI Sbjct: 821 ACPENCPLELYNLMRLCWSKLPADRPSFCSI 851
>ROS_AVISU (P00529) Tyrosine-protein kinase transforming protein ros (EC| 2.7.10.1) Length = 402 Score = 81.3 bits (199), Expect = 3e-15 Identities = 56/154 (36%), Positives = 78/154 (50%), Gaps = 9/154 (5%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLV-DKNWS-----VKVGDFGLSR--FKATTF 521 + LD+ KG YL +H DL N LV +K + VK+GDFGL+R +K + Sbjct: 212 ICLDICKGCVYLEKMR--FIHRDLAARNCLVSEKQYGSCSRVVKIGDFGLARDIYKNDYY 269 Query: 520 ISSKSVAGTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVA 344 WMAPE L DV++FGV++WE LT+ QQP+ GL +V+ V Sbjct: 270 RKRGEGLLPVRWMAPESLIDGVFTNHSDVWAFGVLVWETLTLGQQPYPGLSNIEVLHHVR 329 Query: 343 FQNRRLPIPKDTIPELAALVESCWADDPRQRPSF 242 RL P + ++ L+ CWA DP RP+F Sbjct: 330 -SGGRLESPNNCPDDIRDLMTRCWAQDPHNRPTF 362
>NEK8_MOUSE (Q91ZR4) Serine/threonine-protein kinase Nek8 (EC 2.7.11.1) (Never| in mitosis A-related kinase 8) (NimA-related protein kinase 8) Length = 698 Score = 81.3 bits (199), Expect = 3e-15 Identities = 54/143 (37%), Positives = 83/143 (58%), Gaps = 6/143 (4%) Frame = -1 Query: 640 HCXNPPIVHWDLKTPNMLVDKN-WSVKVGDFGLSRFKATTFISSKS----VAGTPEWMAP 476 H I+H DLKT N+L+DK+ VK+GDFG+S+ +SSKS V GTP +++P Sbjct: 118 HVHTHLILHRDLKTQNILLDKHRMVVKIGDFGISKI-----LSSKSKAYTVVGTPCYISP 172 Query: 475 EFLRGEPSNEKCDVYSFGVILWELLTMQQPWGGLG-PAQVVGAVAFQNRRLPIPKDTIPE 299 E G+P N+K D+++ G +L+EL ++++ + PA V+ ++ PI PE Sbjct: 173 ELCEGKPYNQKSDIWALGCVLYELASLKRAFEAANLPALVLKIMS--GTFAPISDRYSPE 230 Query: 298 LAALVESCWADDPRQRPSFSSIV 230 L LV S + +P QRP S I+ Sbjct: 231 LRQLVLSLLSLEPAQRPPLSHIM 253
>EPHA8_HUMAN (P29322) Ephrin type-A receptor 8 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase) (HEK3) Length = 1005 Score = 80.9 bits (198), Expect = 3e-15 Identities = 55/153 (35%), Positives = 75/153 (49%), Gaps = 4/153 (2%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAG 497 M V G+ YL + VH DL N+LVD N KV DFGLSR ++ + G Sbjct: 740 MLRGVGAGMRYL--SDLGYVHRDLAARNVLVDSNLVCKVSDFGLSRVLEDDPDAAYTTTG 797 Query: 496 TP---EWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRR 329 W APE + + DV+SFGV++WE+L ++P+ + V+ +V + R Sbjct: 798 GKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNRDVISSVE-EGYR 856 Query: 328 LPIPKDTIPELAALVESCWADDPRQRPSFSSIV 230 LP P L L+ CW D QRP FS IV Sbjct: 857 LPAPMGCPHALHQLMLDCWHKDRAQRPRFSQIV 889
>M3K3_MOUSE (Q61084) Mitogen-activated protein kinase kinase kinase 3 (EC| 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3) Length = 626 Score = 80.9 bits (198), Expect = 3e-15 Identities = 50/148 (33%), Positives = 76/148 (51%), Gaps = 3/148 (2%) Frame = -1 Query: 664 VAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISS---KSVAGT 494 + +G++YLH + IVH D+K N+L D +VK+GDFG S+ T +S +SV GT Sbjct: 473 ILEGMSYLH--SNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQTICMSGTGIRSVTGT 530 Query: 493 PEWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQPWGGLGPAQVVGAVAFQNRRLPIPK 314 P WM+PE + GE K DV+S G + E+LT + PW + +A Q +P Sbjct: 531 PYWMSPEVISGEGYGRKADVWSLGCTVVEMLTEKPPWAEYEAMAAIFKIATQPTNPQLPS 590 Query: 313 DTIPELAALVESCWADDPRQRPSFSSIV 230 + + + RQRPS ++ Sbjct: 591 HISEHGRDFLRRIFV-EARQRPSAEELL 617
>M3K3_HUMAN (Q99759) Mitogen-activated protein kinase kinase kinase 3 (EC| 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3) Length = 626 Score = 80.9 bits (198), Expect = 3e-15 Identities = 50/148 (33%), Positives = 76/148 (51%), Gaps = 3/148 (2%) Frame = -1 Query: 664 VAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISS---KSVAGT 494 + +G++YLH + IVH D+K N+L D +VK+GDFG S+ T +S +SV GT Sbjct: 473 ILEGMSYLH--SNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQTICMSGTGMRSVTGT 530 Query: 493 PEWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQPWGGLGPAQVVGAVAFQNRRLPIPK 314 P WM+PE + GE K DV+S G + E+LT + PW + +A Q +P Sbjct: 531 PYWMSPEVISGEGYGRKADVWSLGCTVVEMLTEKPPWAEYEAMAAIFKIATQPTNPQLPS 590 Query: 313 DTIPELAALVESCWADDPRQRPSFSSIV 230 + + + RQRPS ++ Sbjct: 591 HISEHGRDFLRRIFV-EARQRPSAEELL 617
>FGFR3_MOUSE (Q61851) Fibroblast growth factor receptor 3 precursor (EC 2.7.10.1)| (FGFR-3) (Heparin-binding growth factor receptor) Length = 801 Score = 80.9 bits (198), Expect = 3e-15 Identities = 50/153 (32%), Positives = 79/153 (51%), Gaps = 4/153 (2%) Frame = -1 Query: 673 ALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAGT 494 A VA+G+ YL + +H DL N+LV ++ +K+ DFGL+R K+ G Sbjct: 592 AYQVARGMEYL--ASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGR 649 Query: 493 --PEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM--QQPWGGLGPAQVVGAVAFQNRRL 326 +WMAPE L + DV+SFGV+LWE+ T P+ G+ P + + + + R+ Sbjct: 650 LPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTPGGPSPYPGI-PVEELFKLLKEGHRM 708 Query: 325 PIPKDTIPELAALVESCWADDPRQRPSFSSIVD 227 P +L ++ CW P QRP+F +V+ Sbjct: 709 DKPASCTHDLYMIMRECWHAVPSQRPTFKQLVE 741
>EPHA2_MOUSE (Q03145) Ephrin type-A receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2) Length = 977 Score = 80.9 bits (198), Expect = 3e-15 Identities = 51/153 (33%), Positives = 78/153 (50%), Gaps = 4/153 (2%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAG 497 M +A G+ YL N VH DL N+LV+ N KV DFGLSR ++ + +G Sbjct: 720 MLRGIASGMKYL--ANMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEATYTTSG 777 Query: 496 TP---EWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRR 329 W APE + DV+S+G+++WE++T ++P+ L +V+ A+ R Sbjct: 778 GKIPIRWTAPEAISYRKFTSASDVWSYGIVMWEVMTYGERPYWELSNHEVMKAIN-DGFR 836 Query: 328 LPIPKDTIPELAALVESCWADDPRQRPSFSSIV 230 LP P D + L+ CW + +RP F+ IV Sbjct: 837 LPTPMDCPSAIYQLMMQCWQQERSRRPKFADIV 869
>RIPK1_MOUSE (Q60855) Receptor-interacting serine/threonine-protein kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein) Length = 656 Score = 80.9 bits (198), Expect = 3e-15 Identities = 52/170 (30%), Positives = 87/170 (51%), Gaps = 21/170 (12%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKA---------- 530 R+ ++ +G+ YLH + ++H DLK N+LVD+++ +K+ D G++ FK Sbjct: 117 RIIVEAIEGMCYLH--DKGVIHKDLKPENILVDRDFHIKIADLGVASFKTWSKLTKEKDN 174 Query: 529 ----TTFISSKSVAGTPEWMAPEFLR--GEPSNEKCDVYSFGVILWELLTMQQPWGG-LG 371 + + K+ GT +MAPE L EK DVYSFG++LW + ++P+ + Sbjct: 175 KQKEVSSTTKKNNGGTLYYMAPEHLNDINAKPTEKSDVYSFGIVLWAIFAKKEPYENVIC 234 Query: 370 PAQVVGAVAFQNRRLPIPKDTIP----ELAALVESCWADDPRQRPSFSSI 233 Q V + NR P ++ + E+ +L+E CW P RP+F I Sbjct: 235 TEQFVICIKSGNR--PNVEEILEYCPREIISLMERCWQAIPEDRPTFLGI 282
>FGFR2_DROME (Q09147) Fibroblast growth factor receptor homolog 2 precursor (EC| 2.7.10.1) (Protein breathless) (dFGF-R1) Length = 1052 Score = 80.9 bits (198), Expect = 3e-15 Identities = 46/155 (29%), Positives = 84/155 (54%), Gaps = 3/155 (1%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVA 500 + A +A+G+ YL + +H DL N+LV + +K+ DFGL+R T K+ Sbjct: 843 KFAFQIARGMEYL--ASRRCIHRDLAARNVLVSDGYVMKIADFGLARDIQDTEYYRKNTN 900 Query: 499 GTP--EWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRR 329 G +WMAPE L+ + + + DV+S+GV+LWE++T QP+ + A+ + + +R Sbjct: 901 GRLPIKWMAPESLQEKKYDSQSDVWSYGVLLWEIMTYGDQPYPHILSAEELYSYLITGQR 960 Query: 328 LPIPKDTIPELAALVESCWADDPRQRPSFSSIVDT 224 + P + ++ CW + RP+F+ +V++ Sbjct: 961 MEKPAKCSLNIYVVMRQCWHFESCARPTFAELVES 995
>FPS_AVISP (P00541) Tyrosine-protein kinase transforming protein Fps (EC| 2.7.10.2) Length = 533 Score = 80.9 bits (198), Expect = 3e-15 Identities = 52/155 (33%), Positives = 83/155 (53%), Gaps = 6/155 (3%) Frame = -1 Query: 679 RMALDVAKGINYL---HCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKAT-TFISS 512 +M + A G+ YL HC +H DL N LV + ++K+ DFG+SR + + S+ Sbjct: 373 KMMENAAAGMEYLESKHC-----IHRDLAARNCLVTEKNTLKISDFGMSRQEEDGVYAST 427 Query: 511 KSVAGTP-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQ-PWGGLGPAQVVGAVAFQ 338 + P +W APE L + + DV+SFG++LWE ++ P+ L Q A+ Q Sbjct: 428 GGMKQIPVKWTAPEALNYGRYSSESDVWSFGILLWEAFSLGAVPYANLSNQQTREAIE-Q 486 Query: 337 NRRLPIPKDTIPELAALVESCWADDPRQRPSFSSI 233 RL P+ ++ L++ CW DPR+RPSF ++ Sbjct: 487 GVRLEPPEQCPEDVYRLMQRCWEYDPRRRPSFGAV 521
>NEK9_HUMAN (Q8TD19) Serine/threonine-protein kinase Nek9 (EC 2.7.11.1)| (NimA-related protein kinase 9) (Never in mitosis A-related kinase 9) (Nercc1 kinase) (NIMA-related kinase 8) (Nek8) Length = 979 Score = 80.9 bits (198), Expect = 3e-15 Identities = 40/133 (30%), Positives = 76/133 (57%), Gaps = 1/133 (0%) Frame = -1 Query: 622 IVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAGTPEWMAPEFLRGEPSNEK 443 I+H D+KT N+ + K +K+GD+GL++ + + ++++ GTP +M+PE +G N K Sbjct: 172 ILHRDIKTLNIFLTKANLIKLGDYGLAKKLNSEYSMAETLVGTPYYMSPELCQGVKYNFK 231 Query: 442 CDVYSFGVILWELLTMQQPWGGLGPAQVVGAVAFQNRRLPIPKDTIP-ELAALVESCWAD 266 D+++ G +++ELLT+++ + P + + R + + EL +V SC Sbjct: 232 SDIWAVGCVIFELLTLKRTFDATNPLNLCVKIVQGIRAMEVDSSQYSLELIQMVHSCLDQ 291 Query: 265 DPRQRPSFSSIVD 227 DP QRP+ ++D Sbjct: 292 DPEQRPTADELLD 304
>ANPRB_RAT (P16067) Atrial natriuretic peptide receptor B precursor (ANP-B)| (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor) Length = 1047 Score = 80.9 bits (198), Expect = 3e-15 Identities = 57/161 (35%), Positives = 83/161 (51%), Gaps = 16/161 (9%) Frame = -1 Query: 667 DVAKGINYLHCXNPPIV-HWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFIS-SKSVAGT 494 D+ KG+ +LH N I H LK+ N +VD + +K+ D+GL+ F++T S ++ Sbjct: 626 DLVKGMAFLH--NSIISSHGSLKSSNCVVDSRFVLKITDYGLASFRSTAEPDDSHALYAK 683 Query: 493 PEWMAPEFLRGEP----SNEKCDVYSFGVILWELLTMQQPWG----GLGPAQVVGAVAFQ 338 W APE L G P +K DVYSF +IL E+ P+ L P ++V V + Sbjct: 684 KLWTAPELLSGNPLPTTGMQKADVYSFAIILQEIALRSGPFYLEGLDLSPKEIVQKV--R 741 Query: 337 NRRLPIPKDTIP------ELAALVESCWADDPRQRPSFSSI 233 N + P + +I EL L+E CWA DP +RP F I Sbjct: 742 NGQRPYFRPSIDRTQLNEELVLLMERCWAQDPTERPDFGQI 782
>ANPRB_MOUSE (Q6VVW5) Atrial natriuretic peptide receptor B precursor (ANP-B)| (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor) Length = 1047 Score = 80.9 bits (198), Expect = 3e-15 Identities = 57/161 (35%), Positives = 83/161 (51%), Gaps = 16/161 (9%) Frame = -1 Query: 667 DVAKGINYLHCXNPPIV-HWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFIS-SKSVAGT 494 D+ KG+ +LH N I H LK+ N +VD + +K+ D+GL+ F++T S ++ Sbjct: 626 DLVKGMAFLH--NSIISSHGSLKSSNCVVDSRFVLKITDYGLASFRSTAEPDDSHALYAK 683 Query: 493 PEWMAPEFLRGEP----SNEKCDVYSFGVILWELLTMQQPWG----GLGPAQVVGAVAFQ 338 W APE L G P +K DVYSF +IL E+ P+ L P ++V V + Sbjct: 684 KLWTAPELLSGNPLPTTGMQKADVYSFAIILQEIALRSGPFYLEGLDLSPKEIVQKV--R 741 Query: 337 NRRLPIPKDTIP------ELAALVESCWADDPRQRPSFSSI 233 N + P + +I EL L+E CWA DP +RP F I Sbjct: 742 NGQRPYFRPSIDRTQLNEELVLLMERCWAQDPTERPDFGQI 782
>ANPRB_ANGJA (P55202) Atrial natriuretic peptide receptor B precursor (ANP-B)| (ANPRB) (GC-B) (Guanylate cyclase) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor) Length = 1050 Score = 80.9 bits (198), Expect = 3e-15 Identities = 59/161 (36%), Positives = 87/161 (54%), Gaps = 16/161 (9%) Frame = -1 Query: 667 DVAKGINYLHCXNPPI-VHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFIS-SKSVAGT 494 D+ KG+N+LH N I H +LK+ N +VD + +K+ D+GL+ F+++ S ++ Sbjct: 630 DIVKGMNFLH--NSYIGSHGNLKSSNCVVDSRFVLKITDYGLASFRSSCENEDSHALYAK 687 Query: 493 PEWMAPEFL---RGEPSN-EKCDVYSFGVILWELLTMQQPWG----GLGPAQVVGAVAFQ 338 W APE L R P +K DVYSFG+IL E+ P+ L P ++V V + Sbjct: 688 KLWTAPELLIYDRHPPQGTQKGDVYSFGIILQEIALRNGPFYVDGMDLSPKEIVQKV--R 745 Query: 337 NRRLPIPKDTIP------ELAALVESCWADDPRQRPSFSSI 233 N + P + T EL+ L+E CWA+DP RP FS I Sbjct: 746 NGQKPYFRPTTDTSCHSEELSILMEGCWAEDPADRPDFSYI 786
>NEK9_MOUSE (Q8K1R7) Serine/threonine-protein kinase Nek9 (EC 2.7.11.1)| (NimA-related protein kinase 9) (Never in mitosis A-related kinase 9) Length = 984 Score = 80.9 bits (198), Expect = 3e-15 Identities = 40/133 (30%), Positives = 77/133 (57%), Gaps = 1/133 (0%) Frame = -1 Query: 622 IVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAGTPEWMAPEFLRGEPSNEK 443 I+H D+KT N+ + K +K+GD+GL++ + + ++++ GTP +M+PE +G N K Sbjct: 172 ILHRDIKTLNIFLTKANLIKLGDYGLAKKLNSEYSMAETLVGTPYYMSPELCQGVKYNFK 231 Query: 442 CDVYSFGVILWELLTMQQPWGGLGPAQVVGAVAFQNRRLPIPKDTIP-ELAALVESCWAD 266 D+++ G +++ELLT+++ + P + + R + + EL LV +C Sbjct: 232 SDIWAVGCVIFELLTLKRTFDATNPLNLCVKIVQGIRAMEVDSSQYSLELIQLVHACLDQ 291 Query: 265 DPRQRPSFSSIVD 227 DP QRP+ +++D Sbjct: 292 DPEQRPAADALLD 304
>NTRK3_PIG (P24786) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C) Length = 825 Score = 80.9 bits (198), Expect = 3e-15 Identities = 54/151 (35%), Positives = 77/151 (50%), Gaps = 3/151 (1%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSR-FKATTFISSKSVA 500 +A + G+ YL + VH DL T N LV N VK+GDFG+SR +T + Sbjct: 659 IASQICSGMVYL--ASQHFVHRDLATRNCLVGANLLVKIGDFGMSRDVYSTDYYRVGGHT 716 Query: 499 GTP-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRL 326 P WM PE + + DV+SFGVILWE+ T +QPW L +V+ + Q R L Sbjct: 717 MLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGKQPWFQLSNTEVIECIT-QGRVL 775 Query: 325 PIPKDTIPELAALVESCWADDPRQRPSFSSI 233 P+ E+ ++ CW +P+QR + I Sbjct: 776 ERPRVCPKEVYDVMLGCWQREPQQRLNIKEI 806
>VGFR2_RAT (O08775) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Protein-tyrosine kinase receptor flk-1) (Fetal liver kinase 1) Length = 1343 Score = 80.9 bits (198), Expect = 3e-15 Identities = 48/152 (31%), Positives = 80/152 (52%), Gaps = 3/152 (1%) Frame = -1 Query: 673 ALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSR--FKATTFISSKSVA 500 + VAKG+ +L + +H DL N+L+ + VK+ DFGL+R +K ++ Sbjct: 1005 SFQVAKGMEFL--ASRKCIHRDLAARNILLSEKNVVKICDFGLARDIYKDPDYVRKGDPR 1062 Query: 499 GTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRLP 323 +WMAPE + + V+SFGV+LWE+ ++ P+ G+ + + R+ Sbjct: 1063 LPLKWMAPETIFDRIYTIQSGVWSFGVLLWEIFSLGASPYPGVKIDEKFCRRLKEGTRMR 1122 Query: 322 IPKDTIPELAALVESCWADDPRQRPSFSSIVD 227 P T PE+ + CW +DP QRP+FS +V+ Sbjct: 1123 APDYTTPEMYQTMLDCWHEDPNQRPAFSELVE 1154
>FGFR2_XENLA (Q03364) Fibroblast growth factor receptor 2 precursor (EC 2.7.10.1)| (FGFR-2) Length = 813 Score = 80.9 bits (198), Expect = 3e-15 Identities = 48/149 (32%), Positives = 79/149 (53%), Gaps = 3/149 (2%) Frame = -1 Query: 664 VAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAGT--P 491 +A+G+ YL + +H DL N+LV +N +K+ DFGL+R K+ G Sbjct: 600 IARGMEYL--ASQKCIHRDLAARNVLVTENNVMKIADFGLARDVNNIDYYKKTSNGRLPV 657 Query: 490 EWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRLPIPK 314 +WMAPE L + DV+SFGV++WE+ T+ P+ G+ P + + + + R+ P Sbjct: 658 KWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGI-PVEELFKLLKEGHRMDKPA 716 Query: 313 DTIPELAALVESCWADDPRQRPSFSSIVD 227 + EL ++ CW P RP+F +V+ Sbjct: 717 NCTNELYMMMRDCWHAIPSHRPTFKQLVE 745
>MET_RAT (P97523) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1382 Score = 80.5 bits (197), Expect = 4e-15 Identities = 56/151 (37%), Positives = 78/151 (51%), Gaps = 4/151 (2%) Frame = -1 Query: 670 LDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRF---KATTFISSKSVA 500 L VAKG+ YL + VH DL N ++D+ ++VKV DFGL+R K + +K+ A Sbjct: 1187 LQVAKGMKYL--VSKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGA 1244 Query: 499 GTP-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQPWGGLGPAQVVGAVAFQNRRLP 323 P +WMA E L+ + K DV+SFGV+LWEL+T P + Q RRL Sbjct: 1245 KLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITIYLLQGRRLL 1304 Query: 322 IPKDTIPELAALVESCWADDPRQRPSFSSIV 230 P+ L ++ CW RPS S +V Sbjct: 1305 QPEYCPDALYEVMLKCWHPKAEMRPSVSELV 1335
>YES_AVISY (P00527) Tyrosine-protein kinase transforming protein YES (EC| 2.7.10.2) (Fragment) Length = 528 Score = 80.5 bits (197), Expect = 4e-15 Identities = 52/150 (34%), Positives = 80/150 (53%), Gaps = 2/150 (1%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAG 497 MA +A G+ Y+ N +H DL+ N+LV N K+ DFGL+R +++ A Sbjct: 366 MAAQIADGMAYIERMN--YIHRDLRAANILVGDNLVCKIADFGLARLIEDNEYTARQGAK 423 Query: 496 TP-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQ-PWGGLGPAQVVGAVAFQNRRLP 323 P +W APE K DV+SFG++L EL+T + P+ G+ +V+ V + R+P Sbjct: 424 FPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMVNREVLEQVE-RGYRMP 482 Query: 322 IPKDTIPELAALVESCWADDPRQRPSFSSI 233 P+ L L++ CW DP +RP+F I Sbjct: 483 CPQGCPESLHELMKLCWKKDPDERPTFEYI 512
>HCK_MACFA (Q95M30) Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK)| (Hemopoietic cell kinase) Length = 503 Score = 80.5 bits (197), Expect = 4e-15 Identities = 47/146 (32%), Positives = 83/146 (56%), Gaps = 2/146 (1%) Frame = -1 Query: 664 VAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAGTP-E 488 +A+G+ ++ N +H DL+ N+LV + K+ DFGL+R +++ A P + Sbjct: 342 IAEGMAFIEQRN--YIHRDLRAANILVSASLVCKIADFGLARIIEDNEYTAREGAKFPIK 399 Query: 487 WMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQ-PWGGLGPAQVVGAVAFQNRRLPIPKD 311 W APE + S K DV+SFG++L E++T + P+ G+ +V+ A+ + R+P P++ Sbjct: 400 WTAPEAINFGSSTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRALE-RGYRMPRPEN 458 Query: 310 TIPELAALVESCWADDPRQRPSFSSI 233 EL ++ CW + P +RP+F I Sbjct: 459 CPEELYNIMMRCWKNRPEERPTFEYI 484
>YES_CHICK (P09324) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 540 Score = 80.5 bits (197), Expect = 4e-15 Identities = 52/150 (34%), Positives = 80/150 (53%), Gaps = 2/150 (1%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAG 497 MA +A G+ Y+ N +H DL+ N+LV N K+ DFGL+R +++ A Sbjct: 373 MAAQIADGMAYIERMN--YIHRDLRAANILVGDNLVCKIADFGLARLIEDNEYTARQGAK 430 Query: 496 TP-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQ-PWGGLGPAQVVGAVAFQNRRLP 323 P +W APE K DV+SFG++L EL+T + P+ G+ +V+ V + R+P Sbjct: 431 FPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMVNREVLEQVE-RGYRMP 489 Query: 322 IPKDTIPELAALVESCWADDPRQRPSFSSI 233 P+ L L++ CW DP +RP+F I Sbjct: 490 CPQGCPESLHELMKLCWKKDPDERPTFEYI 519
>SRC_AVIS2 (P15054) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 586 Score = 80.5 bits (197), Expect = 4e-15 Identities = 53/147 (36%), Positives = 78/147 (53%), Gaps = 2/147 (1%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAG 497 MA +A G+ Y+ N VH DL+ N+LV +N KV DFGL+R +++ A Sbjct: 365 MAAQIASGMAYVERMN--YVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAK 422 Query: 496 TP-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRLP 323 P +W APE K DV+SFG++L EL T + P+ G+ +V+ V + R+P Sbjct: 423 FPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVE-RGYRMP 481 Query: 322 IPKDTIPELAALVESCWADDPRQRPSF 242 P + L L+ CW DP +RP+F Sbjct: 482 CPPECPESLHDLMCQCWRKDPEERPTF 508
>MOS_MSVMT (P32593) Serine/threonine-protein kinase transforming protein mos| (EC 2.7.11.1) Length = 354 Score = 80.5 bits (197), Expect = 4e-15 Identities = 53/154 (34%), Positives = 77/154 (50%), Gaps = 9/154 (5%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTF---ISSK 509 + +LDV G+ +LH + I+H DLK N+L+ + K+ DFG S+ S Sbjct: 188 KYSLDVVNGLLFLHSQS--ILHLDLKPANILISEQDVCKISDFGCSQKLQVLRGRQASPP 245 Query: 508 SVAGTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQPWGGLGPAQVVGAVAFQNRR 329 + GT APE L+GE + K D+YSFG+ LW++ T + P+ G P V AV N R Sbjct: 246 HIGGTYTHQAPEILKGEIATPKADIYSFGITLWQMTTREVPYSG-EPQYVQYAVVAYNLR 304 Query: 328 LPI------PKDTIPELAALVESCWADDPRQRPS 245 + T L +++SCW QRPS Sbjct: 305 PSLAGAVFTASLTGKALQNIIQSCWEARGLQRPS 338
>SRC_CHICK (P00523) Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2)| (p60-Src) (c-Src) (pp60c-src) Length = 532 Score = 80.5 bits (197), Expect = 4e-15 Identities = 53/147 (36%), Positives = 78/147 (53%), Gaps = 2/147 (1%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAG 497 MA +A G+ Y+ N VH DL+ N+LV +N KV DFGL+R +++ A Sbjct: 365 MAAQIASGMAYVERMN--YVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAK 422 Query: 496 TP-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRLP 323 P +W APE K DV+SFG++L EL T + P+ G+ +V+ V + R+P Sbjct: 423 FPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVE-RGYRMP 481 Query: 322 IPKDTIPELAALVESCWADDPRQRPSF 242 P + L L+ CW DP +RP+F Sbjct: 482 CPPECPESLHDLMCQCWRKDPEERPTF 508
>VGFR2_BRARE (Q8AXB3) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Receptor tyrosine kinase flk-1) Length = 1302 Score = 80.5 bits (197), Expect = 4e-15 Identities = 46/152 (30%), Positives = 82/152 (53%), Gaps = 3/152 (1%) Frame = -1 Query: 673 ALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSR--FKATTFISSKSVA 500 + VAKG+ +L + +H DL N+L+ +N VK+ DFGL+R +K ++ Sbjct: 984 SFQVAKGMEFL--ASRKCIHRDLAARNILLSENNVVKICDFGLARDVYKDPDYVRKGDAR 1041 Query: 499 GTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRLP 323 +WMAPE + + + DV+SFGV++WE+ ++ P+ GL + + R+ Sbjct: 1042 LPLKWMAPEAIFDKIYTTQSDVWSFGVLMWEIFSLGASPYPGLHIDEEFCCRLKEGTRMK 1101 Query: 322 IPKDTIPELAALVESCWADDPRQRPSFSSIVD 227 P+ + E+ + CW +P QRP+F+ +V+ Sbjct: 1102 APEYSSSEIYQTMLDCWHGEPSQRPTFTELVE 1133
>PTK7_CHICK (Q91048) Tyrosine-protein kinase-like 7 precursor (Kinase-like| protein) Length = 1051 Score = 80.5 bits (197), Expect = 4e-15 Identities = 50/150 (33%), Positives = 72/150 (48%), Gaps = 2/150 (1%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAG 497 + VA G+ H N VH DL N LV VKV LS+ + A Sbjct: 891 LCTQVALGME--HLSNGRFVHRDLAARNCLVSAQRQVKVSALSLSKDVYNSEYYHFRQAW 948 Query: 496 TP-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRLP 323 P WM PE + + + K DV+SFGV++WE+ T + P+ L +V+ + +LP Sbjct: 949 IPLRWMPPEAVLEDEFSTKSDVWSFGVLMWEVFTQGEMPYAPLADDEVLAGLKSGKTKLP 1008 Query: 322 IPKDTIPELAALVESCWADDPRQRPSFSSI 233 P+ L L++ CWA P+ RPSFS + Sbjct: 1009 QPEGCPSRLTKLMQRCWAPSPKDRPSFSEL 1038
>FGFR4_MOUSE (Q03142) Fibroblast growth factor receptor 4 precursor (EC 2.7.10.1)| (FGFR-4) (Protein-tyrosine kinase receptor MPK-11) Length = 799 Score = 80.5 bits (197), Expect = 4e-15 Identities = 50/152 (32%), Positives = 80/152 (52%), Gaps = 3/152 (1%) Frame = -1 Query: 673 ALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAGT 494 A VA+G+ YL +H DL N+LV ++ +K+ DFGL+R K+ G Sbjct: 590 AYQVARGMQYLESRK--CIHRDLAARNVLVTEDDVMKIADFGLARGVHHIDYYKKTSNGR 647 Query: 493 --PEWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRLP 323 +WMAPE L + DV+SF ++LWE+ T+ P+ G+ P + + ++ + R+ Sbjct: 648 LPVKWMAPEALFDRVYTHQSDVWSFEILLWEIFTLGGSPYPGI-PVEELFSLLREGHRME 706 Query: 322 IPKDTIPELAALVESCWADDPRQRPSFSSIVD 227 P + EL L+ CW P QRP+F +V+ Sbjct: 707 RPPNCPSELYGLMRECWHAAPSQRPTFKQLVE 738
>SRC_RSVP (P00526) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 80.5 bits (197), Expect = 4e-15 Identities = 53/147 (36%), Positives = 78/147 (53%), Gaps = 2/147 (1%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAG 497 MA +A G+ Y+ N VH DL+ N+LV +N KV DFGL+R +++ A Sbjct: 365 MAAQIASGMAYVERMN--YVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAK 422 Query: 496 TP-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRLP 323 P +W APE K DV+SFG++L EL T + P+ G+ +V+ V + R+P Sbjct: 423 FPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVE-RGYRMP 481 Query: 322 IPKDTIPELAALVESCWADDPRQRPSF 242 P + L L+ CW DP +RP+F Sbjct: 482 CPPECPESLHDLMCQCWRKDPEERPTF 508
>SRC_AVISS (P14084) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 567 Score = 80.5 bits (197), Expect = 4e-15 Identities = 53/147 (36%), Positives = 78/147 (53%), Gaps = 2/147 (1%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAG 497 MA +A G+ Y+ N VH DL+ N+LV +N KV DFGL+R +++ A Sbjct: 365 MAAQIASGMAYVERMN--YVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAK 422 Query: 496 TP-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRLP 323 P +W APE K DV+SFG++L EL T + P+ G+ +V+ V + R+P Sbjct: 423 FPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVE-RGYRMP 481 Query: 322 IPKDTIPELAALVESCWADDPRQRPSF 242 P + L L+ CW DP +RP+F Sbjct: 482 CPPECPESLHDLMCQCWRKDPEERPTF 508
>NTRK3_SAIBB (Q5IS82) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) Length = 825 Score = 80.5 bits (197), Expect = 4e-15 Identities = 54/151 (35%), Positives = 77/151 (50%), Gaps = 3/151 (1%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSR-FKATTFISSKSVA 500 +A +A G+ YL + VH DL T N V N VK+GDFG+SR +T + Sbjct: 659 IASQIASGMVYL--ASQHFVHRDLATRNCXVGANLLVKIGDFGMSRDVYSTDYYRVGGHT 716 Query: 499 GTP-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRL 326 P WM PE + + DV+SFGVILWE+ T +QPW L +V+ + Q R L Sbjct: 717 MLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGKQPWFQLSNTEVIECIT-QGRVL 775 Query: 325 PIPKDTIPELAALVESCWADDPRQRPSFSSI 233 P+ E+ ++ CW +P+QR + I Sbjct: 776 ERPRVCPKEVYDVMLGCWQREPQQRLNIKEI 806
>M3K2_HUMAN (Q9Y2U5) Mitogen-activated protein kinase kinase kinase 2 (EC| 2.7.11.25) (MAPK/ERK kinase kinase 2) (MEK kinase 2) (MEKK 2) Length = 619 Score = 80.5 bits (197), Expect = 4e-15 Identities = 46/119 (38%), Positives = 67/119 (56%), Gaps = 5/119 (4%) Frame = -1 Query: 664 VAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISS---KSVAGT 494 + +G++YLH + IVH D+K N+L D +VK+GDFG S+ T +S KSV GT Sbjct: 467 ILEGVHYLH--SNMIVHRDIKGANILRDSTGNVKLGDFGASKRLQTICLSGTGMKSVTGT 524 Query: 493 PEWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQPWGGLGPAQVVGAVAFQ--NRRLP 323 P WM+PE + GE K D++S + E+LT + PW + +A Q N +LP Sbjct: 525 PYWMSPEVISGEGYGRKADIWSVACTVVEMLTEKPPWAEFEAMAAIFKIATQPTNPKLP 583
>FES_FSVST (P00543) Tyrosine-protein kinase transforming protein Fes (EC| 2.7.10.2) Length = 477 Score = 80.5 bits (197), Expect = 4e-15 Identities = 54/151 (35%), Positives = 81/151 (53%), Gaps = 3/151 (1%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKAT-TFISSKSV 503 +M D A G+ YL + +H DL N LV + +K+ DFG+SR +A + +S + Sbjct: 317 QMVGDAAAGMEYLE--SKCCIHRDLAARNCLVTEKNVLKISDFGMSREEADGVYAASGGL 374 Query: 502 AGTP-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRR 329 P +W APE L + + DV+SFG++LWE ++ P+ L Q V + R Sbjct: 375 RLVPVKWTAPEALNYGRYSSESDVWSFGILLWETFSLGASPYPNLSNQQTREFVE-KGGR 433 Query: 328 LPIPKDTIPELAALVESCWADDPRQRPSFSS 236 LP P+ + L+E CWA +P QRPSFS+ Sbjct: 434 LPCPELCPDAVFRLMEQCWAYEPGQRPSFSA 464
>SRC_RSVPA (P31693) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 522 Score = 80.5 bits (197), Expect = 4e-15 Identities = 53/147 (36%), Positives = 78/147 (53%), Gaps = 2/147 (1%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAG 497 MA +A G+ Y+ N VH DL+ N+LV +N KV DFGL+R +++ A Sbjct: 362 MAAQIASGMAYVERMN--YVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARPGAR 419 Query: 496 TP-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRLP 323 P +W APE K DV+SFG++L EL T + P+ G+ +V+ V + R+P Sbjct: 420 FPVKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNGEVLDRVE-RGYRMP 478 Query: 322 IPKDTIPELAALVESCWADDPRQRPSF 242 P + L L+ CW DP +RP+F Sbjct: 479 CPPECPESLHDLMCQCWRKDPEERPTF 505
>NAK_ARATH (P43293) Probable serine/threonine-protein kinase NAK (EC 2.7.11.1)| Length = 389 Score = 80.5 bits (197), Expect = 4e-15 Identities = 57/171 (33%), Positives = 84/171 (49%), Gaps = 19/171 (11%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSR---FKATTFISSK 509 RMAL A+G+ +LH P +++ D K N+L+D N++ K+ DFGL+R + +S++ Sbjct: 180 RMALGAARGLAFLHNAQPQVIYRDFKASNILLDSNYNAKLSDFGLARDGPMGDNSHVSTR 239 Query: 508 SVAGTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLT------MQQPWGGLGPAQVVGAV 347 V GT + APE+L + K DVYSFGV+L ELL+ QP G Sbjct: 240 -VMGTQGYAAPEYLATGHLSVKSDVYSFGVVLLELLSGRRAIDKNQPVGEHNLVDWARPY 298 Query: 346 AFQNRRLPIPKD----------TIPELAALVESCWADDPRQRPSFSSIVDT 224 RRL D ++A L C + D + RP+ + IV T Sbjct: 299 LTNKRRLLRVMDPRLQGQYSLTRALKIAVLALDCISIDAKSRPTMNEIVKT 349
>SRC_AVIST (P14085) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 556 Score = 80.5 bits (197), Expect = 4e-15 Identities = 53/147 (36%), Positives = 78/147 (53%), Gaps = 2/147 (1%) Frame = -1 Query: 676 MALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAG 497 MA +A G+ Y+ N VH DL+ N+LV +N KV DFGL+R +++ A Sbjct: 365 MAAQIASGMAYVERMN--YVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAK 422 Query: 496 TP-EWMAPEFLRGEPSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRLP 323 P +W APE K DV+SFG++L EL T + P+ G+ +V+ V + R+P Sbjct: 423 FPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVE-RGYRMP 481 Query: 322 IPKDTIPELAALVESCWADDPRQRPSF 242 P + L L+ CW DP +RP+F Sbjct: 482 CPPECPESLHDLMCQCWRKDPEERPTF 508
>MOS_MSVMO (P00538) Serine/threonine-protein kinase transforming protein mos| (EC 2.7.11.1) Length = 374 Score = 80.1 bits (196), Expect = 6e-15 Identities = 53/154 (34%), Positives = 77/154 (50%), Gaps = 9/154 (5%) Frame = -1 Query: 679 RMALDVAKGINYLHCXNPPIVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTF---ISSK 509 + +LDV G+ +LH + I+H DLK N+L+ + K+ DFG S+ S Sbjct: 208 KYSLDVVNGLLFLHSQS--ILHLDLKPANILISEQDVCKISDFGCSQKLQDLRGRQASPP 265 Query: 508 SVAGTPEWMAPEFLRGEPSNEKCDVYSFGVILWELLTMQQPWGGLGPAQVVGAVAFQNRR 329 + GT APE L+GE + K D+YSFG+ LW++ T + P+ G P V AV N R Sbjct: 266 HIGGTYTHQAPEILKGEIATPKADIYSFGITLWQMTTREVPYSG-EPQYVQYAVVAYNLR 324 Query: 328 LPI------PKDTIPELAALVESCWADDPRQRPS 245 + T L +++SCW QRPS Sbjct: 325 PSLAGAVFTASLTGKALQNIIQSCWEARGLQRPS 358
>TNK1_MOUSE (Q99ML2) Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2)| (Kinase of embryonic stem cells) Length = 666 Score = 80.1 bits (196), Expect = 6e-15 Identities = 50/136 (36%), Positives = 68/136 (50%), Gaps = 6/136 (4%) Frame = -1 Query: 622 IVHWDLKTPNMLVDKNWSVKVGDFGLSRFKATTFISSKSVAGTPE-----WMAPEFLRGE 458 +VH DL T N+L+ +KV DFGL R + V G P W APE LR Sbjct: 241 LVHRDLATRNLLLASPRMIKVADFGLVRPLGGA--RGRYVMGGPRPIPYAWCAPESLRQG 298 Query: 457 PSNEKCDVYSFGVILWELLTM-QQPWGGLGPAQVVGAVAFQNRRLPIPKDTIPELAALVE 281 + DV+ FGV LWE+ + ++PW G+ P ++ + RLP P L +L Sbjct: 299 AFSSASDVWMFGVTLWEMFSGGEEPWAGVPPYLILQRLEKDRARLPKPPLCSRALYSLAL 358 Query: 280 SCWADDPRQRPSFSSI 233 CWA P RPSFS++ Sbjct: 359 RCWAPHPADRPSFSNL 374 Score = 31.2 bits (69), Expect = 3.0 Identities = 21/60 (35%), Positives = 30/60 (50%), Gaps = 3/60 (5%) Frame = +3 Query: 372 PRPPHGCCIVRSS--HKITPKLYTSHFSLDGSPRRNSGAIHSGVPATDFD-DMKVVALNL 542 PRPP C + + HK PK +SH G+P + + SG P +D + KVV + L Sbjct: 541 PRPPIICNSSQPTQPHKARPKRESSHNHRTGAPGASKATVPSGGPLSDPEWQRKVVEVEL 600 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 100,395,079 Number of Sequences: 219361 Number of extensions: 2145331 Number of successful extensions: 9544 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 7575 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 7954 length of database: 80,573,946 effective HSP length: 108 effective length of database: 56,882,958 effective search space used: 6655306086 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
