ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
menu 
| Clone Name | rbags9a17 |
|---|---|
| Clone Library Name | barley_pub |
>SRK6_BRAOE (Q09092) Putative serine/threonine-protein kinase receptor precursor| (EC 2.7.11.1) (S-receptor kinase) (SRK) Length = 849 Score = 73.2 bits (178), Expect = 8e-13 Identities = 47/144 (32%), Positives = 78/144 (54%), Gaps = 23/144 (15%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFC-NGEITYQLDIYSVGVI 485 LLD N++PKI+DFG++R F ++ A T+ + GT GY++PE+ G + + D++S GVI Sbjct: 660 LLDKNMIPKISDFGMARIFERDETEANTMKVVGTYGYMSPEYAMYGIFSEKSDVFSFGVI 719 Query: 484 IIEILTGKK--GYLAVD--NVVES--WS----------------NKLEKSQSDVQLKQVR 371 ++EI++GKK G+ +D N + S WS + L S Q ++V Sbjct: 720 VLEIVSGKKNRGFYNLDYENDLLSYVWSRWKEGRALEIVDPVIVDSLSSQPSIFQPQEVL 779 Query: 370 ICAEIGIECTDFNPAKRPGTKNII 299 C +IG+ C RP +++ Sbjct: 780 KCIQIGLLCVQELAEHRPAMSSVV 803
>IRAK4_HUMAN (Q9NWZ3) Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1)| (IRAK-4) (NY-REN-64 antigen) Length = 460 Score = 67.4 bits (163), Expect(2) = 3e-12 Identities = 41/133 (30%), Positives = 65/133 (48%), Gaps = 13/133 (9%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEITYQLDIYSVGVII 482 LLD KI+DFG++R + +T I GT Y+APE GEIT + DIYS GV++ Sbjct: 318 LLDEAFTAKISDFGLARASEKFAQTVMTSRIVGTTAYMAPEALRGEITPKSDIYSFGVVL 377 Query: 481 IEILTG-------KKGYLAVD------NVVESWSNKLEKSQSDVQLKQVRICAEIGIECT 341 +EI+TG ++ L +D + ++ + ++K +D V + +C Sbjct: 378 LEIITGLPAVDEHREPQLLLDIKEEIEDEEKTIEDYIDKKMNDADSTSVEAMYSVASQCL 437 Query: 340 DFNPAKRPGTKNI 302 KRP K + Sbjct: 438 HEKKNKRPDIKKV 450 Score = 23.9 bits (50), Expect(2) = 3e-12 Identities = 10/24 (41%), Positives = 15/24 (62%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFVGWQFGA 639 LH+ + +H D+K ANI + F A Sbjct: 302 LHENHHIHRDIKSANILLDEAFTA 325
>KPRO_MAIZE (P17801) Putative receptor protein kinase ZmPK1 precursor (EC| 2.7.11.1) Length = 817 Score = 69.7 bits (169), Expect = 8e-12 Identities = 46/153 (30%), Positives = 76/153 (49%), Gaps = 24/153 (15%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNG-EITYQLDIYSVGVI 485 LLD PKI DFG+ + + S ++RGTLGY+APE+ + IT ++D+YS GV+ Sbjct: 665 LLDQAFEPKITDFGLVKLLNRGGSTQNVSHVRGTLGYIAPEWVSSLPITAKVDVYSYGVV 724 Query: 484 IIEILTGKK----------GYLAVDNVVESWSNKLE-------------KSQSDVQLKQV 374 ++E+LTG + + + +V S KLE K V Q Sbjct: 725 LLELLTGTRVSELVGGTDEVHSMLRKLVRMLSAKLEGEEQSWIDGYLDSKLNRPVNYVQA 784 Query: 373 RICAEIGIECTDFNPAKRPGTKNIIDRLVSLDE 275 R ++ + C + + +KRP ++ + L+S D+ Sbjct: 785 RTLIKLAVSCLEEDRSKRPTMEHAVQTLLSADD 817
>PSKR_DAUCA (Q8LPB4) Phytosulfokine receptor precursor (EC 2.7.11.1)| (Phytosulfokine LRR receptor kinase) Length = 1021 Score = 67.4 bits (163), Expect(2) = 2e-11 Identities = 43/144 (29%), Positives = 74/144 (51%), Gaps = 16/144 (11%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEI-TYQLDIYSVGVI 485 LL V +ADFG++R + +T ++ GTLGY+ PE+ + TY+ D+YS GV+ Sbjct: 876 LLSDTFVAHLADFGLARLILPYDTH-VTTDLVGTLGYIPPEYGQASVATYKGDVYSFGVV 934 Query: 484 IIEILTGKKGYLAV----DNVVESW--SNKLEKSQSDV---------QLKQVRICAEIGI 350 ++E+LTG++ + SW K EK +S++ +++ + EI Sbjct: 935 LLELLTGRRPMDVCKPRGSRDLISWVLQMKTEKRESEIFDPFIYDKDHAEEMLLVLEIAC 994 Query: 349 ECTDFNPAKRPGTKNIIDRLVSLD 278 C NP RP T+ ++ L ++D Sbjct: 995 RCLGENPKTRPTTQQLVSWLENID 1018 Score = 21.2 bits (43), Expect(2) = 2e-11 Identities = 12/27 (44%), Positives = 16/27 (59%), Gaps = 3/27 (11%) Frame = -2 Query: 710 LHQR---NILHLDLKPANIFVGWQFGA 639 LHQ +ILH D+K +NI + F A Sbjct: 857 LHQSCEPHILHRDIKSSNILLSDTFVA 883
>IRAK4_MOUSE (Q8R4K2) Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1)| (IRAK-4) Length = 459 Score = 63.5 bits (153), Expect(2) = 3e-11 Identities = 30/66 (45%), Positives = 43/66 (65%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEITYQLDIYSVGVII 482 LLD + KI+DFG++R + +T I GT Y+APE GEIT + DIYS GV++ Sbjct: 318 LLDKDFTAKISDFGLARASARLAQTVMTSRIVGTTAYMAPEALRGEITPKSDIYSFGVVL 377 Query: 481 IEILTG 464 +E++TG Sbjct: 378 LELITG 383 Score = 24.3 bits (51), Expect(2) = 3e-11 Identities = 10/24 (41%), Positives = 15/24 (62%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFVGWQFGA 639 LH+ + +H D+K ANI + F A Sbjct: 302 LHENHHIHRDIKSANILLDKDFTA 325
>EXS_ARATH (Q9LYN8) Leucine-rich repeat receptor protein kinase EXS precursor| (EC 2.7.11.1) (Extra sporogenous cells protein) (EXCESS MICROSPOROCYTES1 protein) Length = 1192 Score = 64.7 bits (156), Expect = 3e-10 Identities = 50/146 (34%), Positives = 79/146 (54%), Gaps = 17/146 (11%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEF-CNGEITYQLDIYSVGVI 485 LLDG+ PK+ADFG++R +S TV I GT GY+ PE+ + T + D+YS GVI Sbjct: 1050 LLDGDFEPKVADFGLARLISACESHVSTV-IAGTFGYIPPEYGQSARATTKGDVYSFGVI 1108 Query: 484 IIEILTGKK-----------GYL---AVDNVVESWS-NKLEKSQSDVQLKQVRI-CAEIG 353 ++E++TGK+ G L A+ + + + + ++ V LK ++ +I Sbjct: 1109 LLELVTGKEPTGPDFKESEGGNLVGWAIQKINQGKAVDVIDPLLVSVALKNSQLRLLQIA 1168 Query: 352 IECTDFNPAKRPGTKNIIDRLVSLDE 275 + C PAKRP N++D L +L E Sbjct: 1169 MLCLAETPAKRP---NMLDVLKALKE 1191
>BRL3_ARATH (Q9LJF3) Serine/threonine-protein kinase BRI1-like 3 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 3) Length = 1164 Score = 63.9 bits (154), Expect = 5e-10 Identities = 43/158 (27%), Positives = 75/158 (47%), Gaps = 21/158 (13%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNG-EITYQLDIYSVGVI 485 LLD + V +++DFG++R + + + GT GY+ PE+ T + D+YS GVI Sbjct: 992 LLDQDFVARVSDFGMARLVSALDTHLSVSTLAGTPGYVPPEYYQSFRCTAKGDVYSYGVI 1051 Query: 484 IIEILTGKKGY----LAVDNVVESWSNKLEKSQSDVQLKQVRICAE------------IG 353 ++E+L+GKK DN + W+ +L + + ++ + + I Sbjct: 1052 LLELLSGKKPIDPEEFGEDNNLVGWAKQLYREKRGAEILDPELVTDKSGDVELLHYLKIA 1111 Query: 352 IECTDFNPAKRP---GTKNIIDRLVSLD-ETDSMGGYI 251 +C D P KRP + LV +D E DS+ ++ Sbjct: 1112 SQCLDDRPFKRPTMIQVMTMFKELVQVDTENDSLDEFL 1149
>ANKK1_MOUSE (Q8BZ25) Ankyrin repeat and protein kinase domain-containing| protein 1 (EC 2.7.11.1) Length = 745 Score = 59.3 bits (142), Expect(2) = 5e-10 Identities = 54/184 (29%), Positives = 87/184 (47%), Gaps = 14/184 (7%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVN--IRGTLGYLAPEFC---NGEITYQLDIYS 497 LLD N+ KI+DFG+S+ + + +RGTL Y+ PE N + D+YS Sbjct: 164 LLDNNMHVKISDFGLSKWMEQSTQKQYIERSALRGTLSYIPPEMFLENNKAPGPEYDVYS 223 Query: 496 VGVIIIEILTGKKGYLAVDNV-----VESWSNKLEKSQSDVQLKQVRICAEIGIECTDFN 332 ++I EILT KK Y ++ + V + + SD ++V + C D + Sbjct: 224 FAIVIWEILTQKKPYAGLNMMTIIIRVAAGMRPSLQDVSDEWPEEVHQMVNLMKRCWDQD 283 Query: 331 PAKRPGTKNI---IDRLVSLDETDSMGGYIETSAVTSQ-QAENALEELHQARPKVPGEIS 164 P KRP N+ D L+SL ++ E A+T + + +L + H+ +V EI+ Sbjct: 284 PKKRPCFLNVAVETDMLLSLFQSPMTDPGCE--ALTQKVSCKPSLSQPHKVSKEVNQEIA 341 Query: 163 SEVS 152 VS Sbjct: 342 DSVS 345 Score = 24.3 bits (51), Expect(2) = 5e-10 Identities = 9/13 (69%), Positives = 11/13 (84%) Frame = -2 Query: 695 ILHLDLKPANIFV 657 +LHLDLKP NI + Sbjct: 153 LLHLDLKPGNILL 165
>KPEL_DROME (Q05652) Probable serine/threonine-protein kinase pelle (EC| 2.7.11.1) Length = 501 Score = 61.6 bits (148), Expect(2) = 9e-10 Identities = 47/144 (32%), Positives = 70/144 (48%), Gaps = 21/144 (14%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVN-IRGTLGYLAPEFCN-GEITYQLDIYSVGV 488 LLD L PKI DFG+ R + + VN + GT YL PEF N +++ +D+YS G+ Sbjct: 353 LLDQCLQPKIGDFGLVREGPKSLDAVVEVNKVFGTKIYLPPEFRNFRQLSTGVDVYSFGI 412 Query: 487 IIIEILTG------------KKGYLAVDNVVESWSNK----LEKSQSDVQLKQVRIC--- 365 +++E+ TG KK L D V + W LEK + K++ +C Sbjct: 413 VLLEVFTGRQVTDRVPENETKKNLL--DYVKQQWRQNRMELLEKHLAAPMGKELDMCMCA 470 Query: 364 AEIGIECTDFNPAKRPGTKNIIDR 293 E G+ CT +P RP ++ R Sbjct: 471 IEAGLHCTALDPQDRPSMNAVLKR 494 Score = 21.2 bits (43), Expect(2) = 9e-10 Identities = 7/13 (53%), Positives = 11/13 (84%) Frame = -2 Query: 695 ILHLDLKPANIFV 657 ++H D+KPANI + Sbjct: 342 LIHGDIKPANILL 354
>BCK1_YEAST (Q01389) Serine/threonine-protein kinase BCK1/SLK1/SSP31 (EC| 2.7.11.1) Length = 1478 Score = 59.7 bits (143), Expect(2) = 1e-09 Identities = 37/127 (29%), Positives = 71/127 (55%), Gaps = 6/127 (4%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEITY--QLDIYSVGV 488 LLD + + KI+DFG+SR ++ S + + +RGT+ ++APE + + Y ++DI+S+G Sbjct: 1310 LLDQDGICKISDFGISRKSKDIYSNS-DMTMRGTVFWMAPEMVDTKQGYSAKVDIWSLGC 1368 Query: 487 IIIEILTGKKGYLAVDNVVESWSNKLEKSQSDVQLKQVRICAEIGIE----CTDFNPAKR 320 I++E+ GK+ + ++ V + KS + + + ++IG C + NP KR Sbjct: 1369 IVLEMFAGKRPWSNLEVVAAMFKIGKSKSAPPIPEDTLPLISQIGRNFLDACFEINPEKR 1428 Query: 319 PGTKNII 299 P ++ Sbjct: 1429 PTANELL 1435 Score = 22.7 bits (47), Expect(2) = 1e-09 Identities = 8/18 (44%), Positives = 12/18 (66%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 LH + ILH D+K N+ + Sbjct: 1294 LHSKGILHRDMKADNLLL 1311
>BRL1_ARATH (Q9ZWC8) Serine/threonine-protein kinase BRI1-like 1 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 1) Length = 1166 Score = 62.4 bits (150), Expect = 1e-09 Identities = 37/132 (28%), Positives = 64/132 (48%), Gaps = 17/132 (12%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNG-EITYQLDIYSVGVI 485 LLD + +++DFG++R + + + GT GY+ PE+ T + D+YS GVI Sbjct: 994 LLDEDFEARVSDFGMARLVSALDTHLSVSTLAGTPGYVPPEYYQSFRCTAKGDVYSYGVI 1053 Query: 484 IIEILTGKK----GYLAVDNVVESWSNKLEKSQSDVQLKQVRICAE------------IG 353 ++E+L+GKK G DN + W+ +L + + ++ + + I Sbjct: 1054 LLELLSGKKPIDPGEFGEDNNLVGWAKQLYREKRGAEILDPELVTDKSGDVELFHYLKIA 1113 Query: 352 IECTDFNPAKRP 317 +C D P KRP Sbjct: 1114 SQCLDDRPFKRP 1125
>RLCK7_ARATH (Q9LQQ8) Probable serine/threonine-protein kinase RLCKVII (EC| 2.7.11.1) Length = 423 Score = 61.6 bits (148), Expect = 2e-09 Identities = 37/141 (26%), Positives = 67/141 (47%), Gaps = 20/141 (14%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFC-NGEITYQLDIYSVGVI 485 LL + PK++DFG+++ ++ + GT GY AP++ G++T++ DIYS GV+ Sbjct: 237 LLGEDYQPKLSDFGLAKVGPSGDKTHVSTRVMGTYGYCAPDYAMTGQLTFKSDIYSFGVV 296 Query: 484 IIEILTGKKGYLAVDNV-------VESWSNKLEKS------------QSDVQLKQVRICA 362 ++E++TG+K A+DN + W+ L K Q ++ + Sbjct: 297 LLELITGRK---AIDNTKTRKDQNLVGWARPLFKDRRNFPKMVDPLLQGQYPVRGLYQAL 353 Query: 361 EIGIECTDFNPAKRPGTKNII 299 I C P RP +++ Sbjct: 354 AISAMCVQEQPTMRPVVSDVV 374
>TMK1_ARATH (P43298) Putative receptor protein kinase TMK1 precursor (EC| 2.7.11.1) Length = 942 Score = 61.2 bits (147), Expect = 3e-09 Identities = 46/151 (30%), Positives = 75/151 (49%), Gaps = 22/151 (14%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFC-NGEITYQLDIYSVGVI 485 LL ++ K+ADFG+ R E + +I I GT GYLAPE+ G +T ++D+YS GVI Sbjct: 724 LLGDDMRAKVADFGLVRLAPEGKG-SIETRIAGTFGYLAPEYAVTGRVTTKVDVYSFGVI 782 Query: 484 IIEILTGKKGYLAVDNV-------VESWSNKLEKSQ--------------SDVQLKQVRI 368 ++E++TG+K ++D + SW ++ ++ + L V Sbjct: 783 LMELITGRK---SLDESQPEESIHLVSWFKRMYINKEASFKKAIDTTIDLDEETLASVHT 839 Query: 367 CAEIGIECTDFNPAKRPGTKNIIDRLVSLDE 275 AE+ C P +RP + ++ L SL E Sbjct: 840 VAELAGHCCAREPYQRPDMGHAVNILSSLVE 870
>PSKR_ARATH (Q9ZVR7) Putative phytosulfokine receptor precursor (EC 2.7.11.1)| (Phytosulfokine LRR receptor kinase) Length = 1008 Score = 60.1 bits (144), Expect(2) = 3e-09 Identities = 42/140 (30%), Positives = 71/140 (50%), Gaps = 16/140 (11%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEI-TYQLDIYSVGVI 485 LLD N +ADFG++R ++ ++ ++ GTLGY+ PE+ + TY+ D+YS GV+ Sbjct: 867 LLDENFNSHLADFGLARLMSPYETH-VSTDLVGTLGYIPPEYGQASVATYKGDVYSFGVV 925 Query: 484 IIEILTGK--------KGYLAVDNVVESWSNKLEKSQ-------SDVQLKQVRICAEIGI 350 ++E+LT K KG + + V ++ S+ S K++ EI Sbjct: 926 LLELLTDKRPVDMCKPKGCRDLISWVVKMKHESRASEVFDPLIYSKENDKEMFRVLEIAC 985 Query: 349 ECTDFNPAKRPGTKNIIDRL 290 C NP +RP T+ ++ L Sbjct: 986 LCLSENPKQRPTTQQLVSWL 1005 Score = 20.8 bits (42), Expect(2) = 3e-09 Identities = 8/20 (40%), Positives = 13/20 (65%) Frame = -2 Query: 698 NILHLDLKPANIFVGWQFGA 639 +ILH D+K +NI + F + Sbjct: 855 HILHRDIKSSNILLDENFNS 874
>APK1B_ARATH (P46573) Protein kinase APK1B, chloroplast precursor (EC 2.7.11.1)| Length = 412 Score = 60.8 bits (146), Expect = 4e-09 Identities = 39/155 (25%), Positives = 69/155 (44%), Gaps = 20/155 (12%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEF-CNGEITYQLDIYSVGVI 485 LLD K++DFG+++ ++ I GT GY APE+ G +T + D+YS GV+ Sbjct: 211 LLDSEYNAKLSDFGLAKDGPTGDKSHVSTRIMGTYGYAAPEYLATGHLTTKSDVYSYGVV 270 Query: 484 IIEILTGKKGYLAVD-------NVVESWSNKL------------EKSQSDVQLKQVRICA 362 ++E+L+G++ AVD + W+ L + Q +++ A Sbjct: 271 LLEVLSGRR---AVDKNRPPGEQKLVEWARPLLANKRKLFRVIDNRLQDQYSMEEACKVA 327 Query: 361 EIGIECTDFNPAKRPGTKNIIDRLVSLDETDSMGG 257 + + C F RP ++ L + + GG Sbjct: 328 TLALRCLTFEIKLRPNMNEVVSHLEHIQTLNEAGG 362
>SIRK_ARATH (O64483) Senescence-induced receptor-like serine/threonine-protein| kinase precursor (FLG22-induced receptor-like kinase 1) Length = 876 Score = 60.1 bits (144), Expect = 7e-09 Identities = 40/139 (28%), Positives = 72/139 (51%), Gaps = 15/139 (10%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPE-FCNGEITYQLDIYSVGVI 485 LL+ L K+ADFG+SR F S I+ + G++GYL PE + ++ + D+YS+GV+ Sbjct: 704 LLNEKLQAKMADFGLSRSFSVEGSGQISTVVAGSIGYLDPEYYSTRQMNEKSDVYSLGVV 763 Query: 484 IIEILTGKKGYLA--------VDNVVESWSNKLEKSQSDVQLKQ------VRICAEIGIE 347 ++E++TG+ + D+V +N + D +L++ +EI + Sbjct: 764 LLEVITGQPAIASSKTEKVHISDHVRSILANGDIRGIVDQRLRERYDVGSAWKMSEIALA 823 Query: 346 CTDFNPAKRPGTKNIIDRL 290 CT+ A+RP ++ L Sbjct: 824 CTEHTSAQRPTMSQVVMEL 842
>BAK1_ARATH (Q94F62) BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1| precursor (EC 2.7.11.1) (BRI1-associated receptor kinase 1) (Somatic embryogenesis receptor-like kinase 3) Length = 615 Score = 57.8 bits (138), Expect(2) = 9e-09 Identities = 37/142 (26%), Positives = 76/142 (53%), Gaps = 18/142 (12%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCN-GEITYQLDIYSVGVI 485 LLD + DFG+++ + + +T +RGT+G++APE+ + G+ + + D++ GV+ Sbjct: 423 LLDEEFEAVVGDFGLAKLM-DYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGVM 481 Query: 484 IIEILTGKKGY----LAVDN--VVESWSNKLEKSQS-----DVQL------KQVRICAEI 356 ++E++TG++ + LA D+ ++ W L K + DV L ++V ++ Sbjct: 482 LLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKLEALVDVDLQGNYKDEEVEQLIQV 541 Query: 355 GIECTDFNPAKRPGTKNIIDRL 290 + CT +P +RP ++ L Sbjct: 542 ALLCTQSSPMERPKMSEVVRML 563 Score = 21.6 bits (44), Expect(2) = 9e-09 Identities = 9/19 (47%), Positives = 13/19 (68%) Frame = -2 Query: 695 ILHLDLKPANIFVGWQFGA 639 I+H D+K ANI + +F A Sbjct: 412 IIHRDVKAANILLDEEFEA 430
>PBS1_ARATH (Q9FE20) Serine/threonine-protein kinase PBS1 (EC 2.7.11.1)| (AvrPphB susceptible protein 1) Length = 456 Score = 59.3 bits (142), Expect = 1e-08 Identities = 26/69 (37%), Positives = 44/69 (63%), Gaps = 1/69 (1%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFC-NGEITYQLDIYSVGVI 485 LLD PK++DFG+++ ++ + GT GY APE+ G++T + D+YS GV+ Sbjct: 220 LLDEGFHPKLSDFGLAKLGPTGDKSHVSTRVMGTYGYCAPEYAMTGQLTVKSDVYSFGVV 279 Query: 484 IIEILTGKK 458 +E++TG+K Sbjct: 280 FLELITGRK 288
>CX32_ARATH (P27450) Probable serine/threonine-protein kinase Cx32, chloroplast| precursor (EC 2.7.11.1) Length = 419 Score = 59.3 bits (142), Expect = 1e-08 Identities = 40/141 (28%), Positives = 65/141 (46%), Gaps = 17/141 (12%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEF-CNGEITYQLDIYSVGVI 485 LLD N K++DFG+++ + +T I GT GY APE+ G + + D+++ GV+ Sbjct: 225 LLDSNYDAKLSDFGLAKLGPADEKSHVTTRIMGTYGYAAPEYMATGHLYVKSDVFAFGVV 284 Query: 484 IIEILTGKKGY---------LAVDNVVESWSNKLEKSQ-------SDVQLKQVRICAEIG 353 ++EI+TG + VD + SNK Q K A I Sbjct: 285 LLEIMTGLTAHNTKRPRGQESLVDWLRPELSNKHRVKQIMDKGIKGQYTTKVATEMARIT 344 Query: 352 IECTDFNPAKRPGTKNIIDRL 290 + C + +P RP K +++ L Sbjct: 345 LSCIEPDPKNRPHMKEVVEVL 365
>BRL2_ARATH (Q9ZPS9) Serine/threonine-protein kinase BRI1-like 2 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 2) (Protein VASCULAR HIGHWAY 1) Length = 1143 Score = 59.3 bits (142), Expect = 1e-08 Identities = 43/158 (27%), Positives = 72/158 (45%), Gaps = 31/158 (19%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNG-EITYQLDIYSVGVI 485 LLD ++ +++DFG++R + + + GT GY+ PE+ T + D+YS+GV+ Sbjct: 973 LLDQDMEARVSDFGMARLISALDTHLSVSTLAGTPGYVPPEYYQSFRCTAKGDVYSIGVV 1032 Query: 484 IIEILTGK----KGYLAVDNVVESWS--------------------------NKLEKSQS 395 ++EIL+GK K N+V WS N+ E + Sbjct: 1033 MLEILSGKRPTDKEEFGDTNLV-GWSKMKAREGKHMEVIDEDLLKEGSSESLNEKEGFEG 1091 Query: 394 DVQLKQVRICAEIGIECTDFNPAKRPGTKNIIDRLVSL 281 V +K++ EI + C D P+KRP ++ L L Sbjct: 1092 GVIVKEMLRYLEIALRCVDDFPSKRPNMLQVVASLREL 1129
>M3K9_HUMAN (P80192) Mitogen-activated protein kinase kinase kinase 9 (EC| 2.7.11.25) (Mixed lineage kinase 1) Length = 1104 Score = 58.9 bits (141), Expect = 1e-08 Identities = 34/127 (26%), Positives = 68/127 (53%), Gaps = 1/127 (0%) Frame = -3 Query: 649 NLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEITYQ-LDIYSVGVIIIEI 473 N + KI DFG++R +H R ++ GT ++APE + + D++S GV++ E+ Sbjct: 287 NKILKITDFGLAREWH----RTTKMSAAGTYAWMAPEVIRASMFSKGSDVWSYGVLLWEL 342 Query: 472 LTGKKGYLAVDNVVESWSNKLEKSQSDVQLKQVRICAEIGIECTDFNPAKRPGTKNIIDR 293 LTG+ + +D + ++ + K + A++ +C + +P RP NI+D+ Sbjct: 343 LTGEVPFRGIDGLAVAYGVAMNKLALPIPSTCPEPFAKLMEDCWNPDPHSRPSFTNILDQ 402 Query: 292 LVSLDET 272 L +++E+ Sbjct: 403 LTTIEES 409
>RPK1_IPONI (P93194) Receptor-like protein kinase precursor (EC 2.7.11.1)| Length = 1109 Score = 58.9 bits (141), Expect = 1e-08 Identities = 34/144 (23%), Positives = 70/144 (48%), Gaps = 20/144 (13%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEI-TYQLDIYSVGVI 485 LLD +L P I+DFG+++ + + + ++GT+GY+APE + + + D+YS GV+ Sbjct: 949 LLDSDLEPHISDFGIAKLLDQSATSIPSNTVQGTIGYMAPENAFTTVKSRESDVYSYGVV 1008 Query: 484 IIEILTGKKGY---LAVDNVVESWSNKLEKSQSDVQ----------------LKQVRICA 362 ++E++T KK + + W + ++Q ++QV Sbjct: 1009 LLELITRKKALDPSFNGETDIVGWVRSVWTQTGEIQKIVDPSLLDELIDSSVMEQVTEAL 1068 Query: 361 EIGIECTDFNPAKRPGTKNIIDRL 290 + + C + KRP ++++ +L Sbjct: 1069 SLALRCAEKEVDKRPTMRDVVKQL 1092
>NEK9_HUMAN (Q8TD19) Serine/threonine-protein kinase Nek9 (EC 2.7.11.1)| (NimA-related protein kinase 9) (Never in mitosis A-related kinase 9) (Nercc1 kinase) (NIMA-related kinase 8) (Nek8) Length = 979 Score = 52.4 bits (124), Expect(2) = 4e-08 Identities = 36/130 (27%), Positives = 68/130 (52%), Gaps = 6/130 (4%) Frame = -3 Query: 664 YLLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNG-EITYQLDIYSVGV 488 +L NL+ K+ D+G+++ + S A T + GT Y++PE C G + ++ DI++VG Sbjct: 183 FLTKANLI-KLGDYGLAKKLNSEYSMAET--LVGTPYYMSPELCQGVKYNFKSDIWAVGC 239 Query: 487 IIIEILTGKKGYLAVDNV-----VESWSNKLEKSQSDVQLKQVRICAEIGIECTDFNPAK 323 +I E+LT K+ + A + + + +E S L+ +++ C D +P + Sbjct: 240 VIFELLTLKRTFDATNPLNLCVKIVQGIRAMEVDSSQYSLELIQMVHS----CLDQDPEQ 295 Query: 322 RPGTKNIIDR 293 RP ++DR Sbjct: 296 RPTADELLDR 305 Score = 24.6 bits (52), Expect(2) = 4e-08 Identities = 9/18 (50%), Positives = 13/18 (72%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 +H+ ILH D+K NIF+ Sbjct: 167 IHKAGILHRDIKTLNIFL 184
>NAK_ARATH (P43293) Probable serine/threonine-protein kinase NAK (EC 2.7.11.1)| Length = 389 Score = 57.0 bits (136), Expect = 6e-08 Identities = 38/145 (26%), Positives = 70/145 (48%), Gaps = 18/145 (12%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEF-CNGEITYQLDIYSVGVI 485 LLD N K++DFG++R + ++ + GT GY APE+ G ++ + D+YS GV+ Sbjct: 210 LLDSNYNAKLSDFGLARDGPMGDNSHVSTRVMGTQGYAAPEYLATGHLSVKSDVYSFGVV 269 Query: 484 IIEILTGKKGY-----LAVDNVVESW-----SNKLE-------KSQSDVQLKQVRICAEI 356 ++E+L+G++ + N+V+ W +NK + Q L + A + Sbjct: 270 LLELLSGRRAIDKNQPVGEHNLVD-WARPYLTNKRRLLRVMDPRLQGQYSLTRALKIAVL 328 Query: 355 GIECTDFNPAKRPGTKNIIDRLVSL 281 ++C + RP I+ + L Sbjct: 329 ALDCISIDAKSRPTMNEIVKTMEEL 353
>PKNB_MYCLE (P54744) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 622 Score = 48.5 bits (114), Expect(2) = 6e-08 Identities = 23/64 (35%), Positives = 39/64 (60%), Gaps = 1/64 (1%) Frame = -3 Query: 637 KIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGE-ITYQLDIYSVGVIIIEILTGK 461 K+ DFG++R + S T + GT YL+PE G+ + + D+YS+G ++ EILTG+ Sbjct: 153 KVMDFGIARAIADSTSVTQTAAVIGTAQYLSPEQARGDSVDARSDVYSLGCVLYEILTGE 212 Query: 460 KGYL 449 ++ Sbjct: 213 PPFI 216 Score = 28.1 bits (61), Expect(2) = 6e-08 Identities = 10/17 (58%), Positives = 13/17 (76%) Frame = -2 Query: 707 HQRNILHLDLKPANIFV 657 HQ I+H D+KPANI + Sbjct: 130 HQNGIIHRDVKPANIMI 146
>BRI1_LYCPE (Q8L899) Systemin receptor SR160 precursor (EC 2.7.11.1)| (Brassinosteroid LRR receptor kinase) Length = 1207 Score = 56.6 bits (135), Expect = 7e-08 Identities = 40/159 (25%), Positives = 76/159 (47%), Gaps = 17/159 (10%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNG-EITYQLDIYSVGVI 485 LLD NL +++DFG++R M + + GT GY+ PE+ + + D+YS GV+ Sbjct: 1021 LLDENLEARVSDFGMARLMSAMDTHLSVSTLAGTPGYVPPEYYQSFRCSTKGDVYSYGVV 1080 Query: 484 IIEILTGKK-------------GYL---AVDNVVESWSNKLEKSQSDVQLKQVRICAEIG 353 ++E+LTGK+ G++ A + + + +L K + ++++ ++ ++ Sbjct: 1081 LLELLTGKQPTDSADFGDNNLVGWVKLHAKGKITDVFDRELLKEDASIEIELLQ-HLKVA 1139 Query: 352 IECTDFNPAKRPGTKNIIDRLVSLDETDSMGGYIETSAV 236 C D KRP +I + E + G TS + Sbjct: 1140 CACLDDRHWKRP---TMIQVMAMFKEIQAGSGMDSTSTI 1175
>BRI1_LYCES (Q8GUQ5) Brassinosteroid LRR receptor kinase precursor (EC 2.7.11.1)| (tBRI1) (Altered brassinolide sensitivity 1) (Systemin receptor SR160) Length = 1207 Score = 56.6 bits (135), Expect = 7e-08 Identities = 40/159 (25%), Positives = 76/159 (47%), Gaps = 17/159 (10%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNG-EITYQLDIYSVGVI 485 LLD NL +++DFG++R M + + GT GY+ PE+ + + D+YS GV+ Sbjct: 1021 LLDENLEARVSDFGMARLMSAMDTHLSVSTLAGTPGYVPPEYYQSFRCSTKGDVYSYGVV 1080 Query: 484 IIEILTGKK-------------GYL---AVDNVVESWSNKLEKSQSDVQLKQVRICAEIG 353 ++E+LTGK+ G++ A + + + +L K + ++++ ++ ++ Sbjct: 1081 LLELLTGKQPTDSADFGDNNLVGWVKLHAKGKITDVFDRELLKEDASIEIELLQ-HLKVA 1139 Query: 352 IECTDFNPAKRPGTKNIIDRLVSLDETDSMGGYIETSAV 236 C D KRP +I + E + G TS + Sbjct: 1140 CACLDDRHWKRP---TMIQVMAMFKEIQAGSGMDSTSTI 1175
>ANKK1_HUMAN (Q8NFD2) Ankyrin repeat and protein kinase domain-containing| protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288) Length = 765 Score = 52.0 bits (123), Expect(2) = 7e-08 Identities = 47/181 (25%), Positives = 83/181 (45%), Gaps = 11/181 (6%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVN---IRGTLGYLAPEF---CNGEITYQLDIY 500 LLD N+ KI+DFG+S+ + E +R + +RG L Y+ PE N + D+Y Sbjct: 152 LLDSNMHVKISDFGLSK-WMEQSTRMQYIERSALRGMLSYIPPEMFLESNKAPGPKYDVY 210 Query: 499 SVGVIIIEILTGKKGYLAVDNV-----VESWSNKLEKSQSDVQLKQVRICAEIGIECTDF 335 S ++I E+LT KK Y + + V + + SD + + ++ C D Sbjct: 211 SFAIVIWELLTQKKPYSGFNMMMIIIRVAAGMRPSLQPVSDQWPSEAQQMVDLMKRCWDQ 270 Query: 334 NPAKRPGTKNIIDRLVSLDETDSMGGYIETSAVTSQQAENALEELHQARPKVPGEISSEV 155 +P KRP +I ETD + +++ + A + + + PGE++ ++ Sbjct: 271 DPKKRPCFLDI------TIETDILLSLLQSRVAVPESKALARKVSCKLSLRQPGEVNEDI 324 Query: 154 S 152 S Sbjct: 325 S 325 Score = 24.3 bits (51), Expect(2) = 7e-08 Identities = 9/13 (69%), Positives = 11/13 (84%) Frame = -2 Query: 695 ILHLDLKPANIFV 657 +LHLDLKP NI + Sbjct: 141 LLHLDLKPGNILL 153
>MOS_MSVTS (P10421) Serine/threonine-protein kinase transforming protein mos| (EC 2.7.11.1) Length = 342 Score = 42.7 bits (99), Expect(2) = 8e-08 Identities = 25/65 (38%), Positives = 38/65 (58%), Gaps = 1/65 (1%) Frame = -3 Query: 643 VPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEI-TYQLDIYSVGVIIIEILT 467 V KI+DFG S+ +++ R +I GT + APE GEI T + DIYS G+ + ++ T Sbjct: 211 VCKISDFGCSQKLQDLRCRQSPHHIGGTYTHQAPEILKGEIATPKADIYSFGITLWQMTT 270 Query: 466 GKKGY 452 + Y Sbjct: 271 REVPY 275 Score = 33.5 bits (75), Expect(2) = 8e-08 Identities = 14/21 (66%), Positives = 17/21 (80%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFVGWQ 648 LH ++ILHLDLKPANI + Q Sbjct: 189 LHSQSILHLDLKPANILISEQ 209
>NEK9_XENLA (Q7ZZC8) Serine/threonine-protein kinase Nek9 (EC 2.7.11.1)| (NimA-related protein kinase 9) (XNek9) (Nercc1 kinase) Length = 944 Score = 51.2 bits (121), Expect(2) = 9e-08 Identities = 38/132 (28%), Positives = 68/132 (51%), Gaps = 8/132 (6%) Frame = -3 Query: 664 YLLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNG-EITYQLDIYSVGV 488 +L NL+ K+ D+G+++ S A T GTL Y++PE C G + +++ DI++VG Sbjct: 165 FLTKANLI-KLGDYGLAKQLSSEYSMAETCV--GTLYYMSPEICQGVKYSFKSDIWAVGC 221 Query: 487 IIIEILTGKKGY-------LAVDNVVESWSNKLEKSQSDVQLKQVRICAEIGIECTDFNP 329 ++ E+LT + + L V V +W+ L+ + +L E+ C + +P Sbjct: 222 VLYELLTLTRTFDATNPLNLCVKIVQGNWAVGLDNTVYTQEL------IEVVHACLEQDP 275 Query: 328 AKRPGTKNIIDR 293 KRP I++R Sbjct: 276 EKRPTADEILER 287 Score = 24.6 bits (52), Expect(2) = 9e-08 Identities = 9/18 (50%), Positives = 13/18 (72%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 +H+ ILH D+K NIF+ Sbjct: 149 IHKAGILHRDIKTLNIFL 166
>ST17B_MOUSE (Q8BG48) Serine/threonine-protein kinase 17B (EC 2.7.11.1) (DAP| kinase-related apoptosis-inducing protein kinase 2) Length = 372 Score = 43.5 bits (101), Expect(2) = 1e-07 Identities = 37/121 (30%), Positives = 59/121 (48%), Gaps = 8/121 (6%) Frame = -3 Query: 637 KIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGE-ITYQLDIYSVGVIIIEILTGK 461 KI DFG+SR ++ + + I GT YLAPE N + IT D++++G+I +LT Sbjct: 176 KIVDFGMSR---KIGNASELREIMGTPEYLAPEILNYDPITTATDMWNIGIIAYMLLTHT 232 Query: 460 KGYLAVDNVVESWSNKLEKSQSDVQLKQVRICAEIGIECTDF-------NPAKRPGTKNI 302 ++ DN L SQ +V + + + + TDF NP KRP ++ Sbjct: 233 SPFVGEDN----QETYLNISQVNVDYSE-EMFSSVSQLATDFIQSLLVKNPEKRPTAESC 287 Query: 301 I 299 + Sbjct: 288 L 288 Score = 32.3 bits (72), Expect(2) = 1e-07 Identities = 13/18 (72%), Positives = 15/18 (83%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 LHQ NI+HLDLKP NI + Sbjct: 149 LHQNNIVHLDLKPQNILL 166
>ST17B_RAT (Q91XS8) Serine/threonine-protein kinase 17B (EC 2.7.11.1) (DAP| kinase-related apoptosis-inducing protein kinase 2) Length = 371 Score = 43.5 bits (101), Expect(2) = 1e-07 Identities = 37/121 (30%), Positives = 59/121 (48%), Gaps = 8/121 (6%) Frame = -3 Query: 637 KIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGE-ITYQLDIYSVGVIIIEILTGK 461 KI DFG+SR ++ + + I GT YLAPE N + IT D++++G+I +LT Sbjct: 176 KIVDFGMSR---KIGNASELREIMGTPEYLAPEILNYDPITTATDMWNIGIIAYMLLTHT 232 Query: 460 KGYLAVDNVVESWSNKLEKSQSDVQLKQVRICAEIGIECTDF-------NPAKRPGTKNI 302 ++ DN L SQ +V + + + + TDF NP KRP ++ Sbjct: 233 SPFVGEDN----QETYLNISQVNVDYSE-EMFSSVSQLATDFIQSLLVKNPEKRPTAESC 287 Query: 301 I 299 + Sbjct: 288 L 288 Score = 32.3 bits (72), Expect(2) = 1e-07 Identities = 13/18 (72%), Positives = 15/18 (83%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 LHQ NI+HLDLKP NI + Sbjct: 149 LHQNNIVHLDLKPQNILL 166
>MOS_RAT (P00539) Proto-oncogene serine/threonine-protein kinase mos (EC| 2.7.11.1) (c-mos) (Oocyte maturation factor mos) Length = 339 Score = 42.7 bits (99), Expect(2) = 1e-07 Identities = 25/65 (38%), Positives = 38/65 (58%), Gaps = 1/65 (1%) Frame = -3 Query: 643 VPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEI-TYQLDIYSVGVIIIEILT 467 V KI+DFG S+ +++ R +I GT + APE GEI T + DIYS G+ + ++ T Sbjct: 209 VCKISDFGCSQKLQDLRCRPSLHHIGGTYTHQAPELLKGEIATPKADIYSFGITLWQMTT 268 Query: 466 GKKGY 452 + Y Sbjct: 269 REVPY 273 Score = 32.7 bits (73), Expect(2) = 1e-07 Identities = 13/18 (72%), Positives = 16/18 (88%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 LH ++ILHLDLKPANI + Sbjct: 187 LHSQSILHLDLKPANILI 204
>NEK9_MOUSE (Q8K1R7) Serine/threonine-protein kinase Nek9 (EC 2.7.11.1)| (NimA-related protein kinase 9) (Never in mitosis A-related kinase 9) Length = 984 Score = 50.4 bits (119), Expect(2) = 2e-07 Identities = 38/131 (29%), Positives = 69/131 (52%), Gaps = 8/131 (6%) Frame = -3 Query: 664 YLLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNG-EITYQLDIYSVGV 488 +L NL+ K+ D+G+++ + S A T + GT Y++PE C G + ++ DI++VG Sbjct: 183 FLTKANLI-KLGDYGLAKKLNSEYSMAET--LVGTPYYMSPELCQGVKYNFKSDIWAVGC 239 Query: 487 IIIEILTGKKGY-------LAVDNVVESWSNKLEKSQSDVQLKQVRICAEIGIECTDFNP 329 +I E+LT K+ + L V V + +++ SQ ++L Q + C D +P Sbjct: 240 VIFELLTLKRTFDATNPLNLCVKIVQGIRAMEVDSSQYSLELIQ------LVHACLDQDP 293 Query: 328 AKRPGTKNIID 296 +RP ++D Sbjct: 294 EQRPAADALLD 304 Score = 24.6 bits (52), Expect(2) = 2e-07 Identities = 9/18 (50%), Positives = 13/18 (72%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 +H+ ILH D+K NIF+ Sbjct: 167 IHKAGILHRDIKTLNIFL 184
>ST17B_HUMAN (O94768) Serine/threonine-protein kinase 17B (EC 2.7.11.1) (DAP| kinase-related apoptosis-inducing protein kinase 2) Length = 372 Score = 42.7 bits (99), Expect(2) = 2e-07 Identities = 39/116 (33%), Positives = 54/116 (46%), Gaps = 9/116 (7%) Frame = -3 Query: 637 KIADFGVSRCF-HEMQSRAITVNIRGTLGYLAPEFCNGE-ITYQLDIYSVGVIIIEILTG 464 KI DFG+SR H + R I GT YLAPE N + IT D++++G+I +LT Sbjct: 176 KIVDFGMSRKIGHACELR----EIMGTPEYLAPEILNYDPITTATDMWNIGIIAYMLLTH 231 Query: 463 KKGYLAVDNVVESWSNKLEKSQSDVQLKQVRICAEIGIECTDF-------NPAKRP 317 ++ DN L SQ +V + + + TDF NP KRP Sbjct: 232 TSPFVGEDN----QETYLNISQVNVDYSE-ETFSSVSQLATDFIQSLLVKNPEKRP 282 Score = 32.3 bits (72), Expect(2) = 2e-07 Identities = 13/18 (72%), Positives = 15/18 (83%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 LHQ NI+HLDLKP NI + Sbjct: 149 LHQNNIVHLDLKPQNILL 166
>LRRK1_MOUSE (Q3UHC2) Leucine-rich repeat serine/threonine-protein kinase 1 (EC| 2.7.11.1) Length = 2014 Score = 49.3 bits (116), Expect(2) = 2e-07 Identities = 34/121 (28%), Positives = 62/121 (51%), Gaps = 5/121 (4%) Frame = -3 Query: 637 KIADFGVSR-CFHEMQSRAITVNIRGTLGYLAPEFCNGEITY--QLDIYSVGVIIIEILT 467 K++D+G+SR FHE + + GT GY APE I Y ++D++S G+++ E+L+ Sbjct: 1406 KLSDYGISRQSFHEG-----ALGVEGTPGYQAPEI-RPRIVYDEKVDMFSYGMVLYELLS 1459 Query: 466 GKKGYLAVDN--VVESWSNKLEKSQSDVQLKQVRICAEIGIECTDFNPAKRPGTKNIIDR 293 G++ L +V+ S + + Q + +EC D P KRP +++ + Sbjct: 1460 GQRPALGHHQLQIVKKLSKGIRPVLGQPEEVQFHRLQALMMECWDTKPEKRPLALSVVSQ 1519 Query: 292 L 290 + Sbjct: 1520 M 1520 Score = 25.4 bits (54), Expect(2) = 2e-07 Identities = 12/24 (50%), Positives = 15/24 (62%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFVGWQFGA 639 LH++NI+ DLK NI V W A Sbjct: 1377 LHKKNIIFCDLKSDNILV-WSLSA 1399
>M3K12_MOUSE (Q60700) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 888 Score = 52.8 bits (125), Expect(2) = 2e-07 Identities = 36/119 (30%), Positives = 61/119 (51%), Gaps = 4/119 (3%) Frame = -3 Query: 643 VPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGE-ITYQLDIYSVGVIIIEILT 467 V KI+DFG S+ E+ ++ ++ GT+ ++APE E ++ ++DI+S GV++ E+LT Sbjct: 282 VVKISDFGTSK---ELSDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLT 338 Query: 466 GKKGYLAVDNVVESW---SNKLEKSQSDVQLKQVRICAEIGIECTDFNPAKRPGTKNII 299 G+ Y VD+ W SN L +I +C + P RP + I+ Sbjct: 339 GEIPYKDVDSSAIIWGVGSNSLHLPVPSSCPDGFKILLR---QCWNSKPRNRPSFRQIL 394 Score = 21.9 bits (45), Expect(2) = 2e-07 Identities = 8/18 (44%), Positives = 11/18 (61%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 LH I+H DLK N+ + Sbjct: 260 LHLHKIIHRDLKSPNMLI 277
>M3K12_HUMAN (Q12852) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 859 Score = 52.8 bits (125), Expect(2) = 2e-07 Identities = 36/119 (30%), Positives = 61/119 (51%), Gaps = 4/119 (3%) Frame = -3 Query: 643 VPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGE-ITYQLDIYSVGVIIIEILT 467 V KI+DFG S+ E+ ++ ++ GT+ ++APE E ++ ++DI+S GV++ E+LT Sbjct: 249 VVKISDFGTSK---ELSDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLT 305 Query: 466 GKKGYLAVDNVVESW---SNKLEKSQSDVQLKQVRICAEIGIECTDFNPAKRPGTKNII 299 G+ Y VD+ W SN L +I +C + P RP + I+ Sbjct: 306 GEIPYKDVDSSAIIWGVGSNSLHLPVPSSCPDGFKILLR---QCWNSKPRNRPSFRQIL 361 Score = 21.9 bits (45), Expect(2) = 2e-07 Identities = 8/18 (44%), Positives = 11/18 (61%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 LH I+H DLK N+ + Sbjct: 227 LHLHKIIHRDLKSPNMLI 244
>BRI1_ARATH (O22476) BRASSINOSTEROID INSENSITIVE 1 precursor (EC 2.7.11.1)| (AtBRI1) (Brassinosteroid LRR receptor kinase) Length = 1196 Score = 55.1 bits (131), Expect = 2e-07 Identities = 26/69 (37%), Positives = 43/69 (62%), Gaps = 1/69 (1%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNG-EITYQLDIYSVGVI 485 LLD NL +++DFG++R M + + GT GY+ PE+ + + D+YS GV+ Sbjct: 1016 LLDENLEARVSDFGMARLMSAMDTHLSVSTLAGTPGYVPPEYYQSFRCSTKGDVYSYGVV 1075 Query: 484 IIEILTGKK 458 ++E+LTGK+ Sbjct: 1076 LLELLTGKR 1084
>M3K13_PONPY (Q5R8X7) Mitogen-activated protein kinase kinase kinase 13 (EC| 2.7.11.25) Length = 966 Score = 51.2 bits (121), Expect(2) = 3e-07 Identities = 27/73 (36%), Positives = 46/73 (63%), Gaps = 1/73 (1%) Frame = -3 Query: 637 KIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGE-ITYQLDIYSVGVIIIEILTGK 461 KI+DFG S+ E+ ++ ++ GT+ +LAPE E ++ ++DI+S GV++ E+LTG+ Sbjct: 294 KISDFGTSK---ELSDKSTKMSFAGTVAWLAPEVIRNEPVSEKVDIWSFGVVLWELLTGE 350 Query: 460 KGYLAVDNVVESW 422 Y VD+ W Sbjct: 351 IPYKDVDSSAIIW 363 Score = 23.1 bits (48), Expect(2) = 3e-07 Identities = 9/18 (50%), Positives = 11/18 (61%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 LH I+H DLK N+ V Sbjct: 270 LHLHKIIHRDLKSPNVLV 287
>M3K12_RAT (Q63796) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 888 Score = 52.4 bits (124), Expect(2) = 3e-07 Identities = 36/119 (30%), Positives = 61/119 (51%), Gaps = 4/119 (3%) Frame = -3 Query: 643 VPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGE-ITYQLDIYSVGVIIIEILT 467 V KI+DFG S+ E+ ++ ++ GT+ ++APE E ++ ++DI+S GV++ E+LT Sbjct: 282 VVKISDFGTSK---ELSDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLT 338 Query: 466 GKKGYLAVDNVVESW---SNKLEKSQSDVQLKQVRICAEIGIECTDFNPAKRPGTKNII 299 G+ Y VD+ W SN L +I +C + P RP + I+ Sbjct: 339 GEIPYKDVDSSAIIWGVGSNSLHLPVPSSCPDGFKILLR---QCWNRKPRNRPSFRQIL 394 Score = 21.9 bits (45), Expect(2) = 3e-07 Identities = 8/18 (44%), Positives = 11/18 (61%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 LH I+H DLK N+ + Sbjct: 260 LHLHKIIHRDLKSPNMLI 277
>MOS_MSVMO (P00538) Serine/threonine-protein kinase transforming protein mos| (EC 2.7.11.1) Length = 374 Score = 40.8 bits (94), Expect(2) = 3e-07 Identities = 26/66 (39%), Positives = 39/66 (59%), Gaps = 2/66 (3%) Frame = -3 Query: 643 VPKIADFGVSRCFHEMQSR-AITVNIRGTLGYLAPEFCNGEI-TYQLDIYSVGVIIIEIL 470 V KI+DFG S+ +++ R A +I GT + APE GEI T + DIYS G+ + ++ Sbjct: 242 VCKISDFGCSQKLQDLRGRQASPPHIGGTYTHQAPEILKGEIATPKADIYSFGITLWQMT 301 Query: 469 TGKKGY 452 T + Y Sbjct: 302 TREVPY 307 Score = 33.5 bits (75), Expect(2) = 3e-07 Identities = 14/21 (66%), Positives = 17/21 (80%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFVGWQ 648 LH ++ILHLDLKPANI + Q Sbjct: 220 LHSQSILHLDLKPANILISEQ 240
>LRRK1_HUMAN (Q38SD2) Leucine-rich repeat serine/threonine-protein kinase 1 (EC| 2.7.11.1) Length = 2038 Score = 49.7 bits (117), Expect(2) = 3e-07 Identities = 34/121 (28%), Positives = 62/121 (51%), Gaps = 5/121 (4%) Frame = -3 Query: 637 KIADFGVSR-CFHEMQSRAITVNIRGTLGYLAPEFCNGEITY--QLDIYSVGVIIIEILT 467 K++D+G+SR FHE + + GT GY APE I Y ++D++S G+++ E+L+ Sbjct: 1429 KLSDYGISRQSFHEG-----ALGVEGTPGYQAPEI-RPRIVYDEKVDMFSYGMVLYELLS 1482 Query: 466 GKKGYLAVDN--VVESWSNKLEKSQSDVQLKQVRICAEIGIECTDFNPAKRPGTKNIIDR 293 G++ L + + S + + Q R + +EC D P KRP +++ + Sbjct: 1483 GQRPALGHHQLQIAKKLSKGIRPVLGQPEEVQFRRLQALMMECWDTKPEKRPLALSVVSQ 1542 Query: 292 L 290 + Sbjct: 1543 M 1543 Score = 24.3 bits (51), Expect(2) = 3e-07 Identities = 10/18 (55%), Positives = 13/18 (72%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 LH++NI+ DLK NI V Sbjct: 1400 LHKKNIIFCDLKSDNILV 1417
>RLK5_ARATH (P47735) Receptor-like protein kinase 5 precursor (EC 2.7.11.1)| Length = 999 Score = 52.4 bits (124), Expect(2) = 4e-07 Identities = 38/136 (27%), Positives = 68/136 (50%), Gaps = 15/136 (11%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITV--NIRGTLGYLAPEFCNG-EITYQLDIYSVG 491 LLD + K+ADFG+++ S+ I G+ GY+APE+ + + DIYS G Sbjct: 826 LLDSDYGAKVADFGIAKVGQMSGSKTPEAMSGIAGSCGYIAPEYVYTLRVNEKSDIYSFG 885 Query: 490 VIIIEILTGKK---GYLAVDNVVESWSNKLEK--------SQSDVQLK-QVRICAEIGIE 347 V+++E++TGK+ L ++ + L+K + D++ K ++ IG+ Sbjct: 886 VVLLELVTGKQPTDSELGDKDMAKWVCTALDKCGLEPVIDPKLDLKFKEEISKVIHIGLL 945 Query: 346 CTDFNPAKRPGTKNII 299 CT P RP + ++ Sbjct: 946 CTSPLPLNRPSMRKVV 961 Score = 21.2 bits (43), Expect(2) = 4e-07 Identities = 8/19 (42%), Positives = 13/19 (68%) Frame = -2 Query: 695 ILHLDLKPANIFVGWQFGA 639 I+H D+K +NI + +GA Sbjct: 815 IVHRDVKSSNILLDSDYGA 833
>M3K13_HUMAN (O43283) Mitogen-activated protein kinase kinase kinase 13 (EC| 2.7.11.25) (Mixed lineage kinase) (MLK) (Leucine zipper-bearing kinase) Length = 966 Score = 50.4 bits (119), Expect(2) = 4e-07 Identities = 26/73 (35%), Positives = 46/73 (63%), Gaps = 1/73 (1%) Frame = -3 Query: 637 KIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGE-ITYQLDIYSVGVIIIEILTGK 461 KI+DFG S+ E+ ++ ++ GT+ ++APE E ++ ++DI+S GV++ E+LTG+ Sbjct: 294 KISDFGTSK---ELSDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGE 350 Query: 460 KGYLAVDNVVESW 422 Y VD+ W Sbjct: 351 IPYKDVDSSAIIW 363 Score = 23.1 bits (48), Expect(2) = 4e-07 Identities = 9/18 (50%), Positives = 11/18 (61%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 LH I+H DLK N+ V Sbjct: 270 LHLHKIIHRDLKSPNVLV 287
>MOS_MSVMM (P00537) Serine/threonine-protein kinase transforming protein mos| (EC 2.7.11.1) Length = 376 Score = 40.0 bits (92), Expect(2) = 5e-07 Identities = 26/66 (39%), Positives = 39/66 (59%), Gaps = 2/66 (3%) Frame = -3 Query: 643 VPKIADFGVSRCFHEMQSR-AITVNIRGTLGYLAPEFCNGEI-TYQLDIYSVGVIIIEIL 470 V KI+DFG S+ +++ R A +I GT + APE GEI T + DIYS G+ + ++ Sbjct: 242 VCKISDFGCSQKLQDLRCRQASPHHIGGTYTHQAPEILKGEIATPKADIYSFGITLWQMT 301 Query: 469 TGKKGY 452 T + Y Sbjct: 302 TREVPY 307 Score = 33.5 bits (75), Expect(2) = 5e-07 Identities = 14/21 (66%), Positives = 17/21 (80%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFVGWQ 648 LH ++ILHLDLKPANI + Q Sbjct: 220 LHSQSILHLDLKPANILISEQ 240
>MOS_MSVMH (P07331) Serine/threonine-protein kinase transforming protein mos| (EC 2.7.11.1) Length = 374 Score = 40.0 bits (92), Expect(2) = 5e-07 Identities = 26/66 (39%), Positives = 39/66 (59%), Gaps = 2/66 (3%) Frame = -3 Query: 643 VPKIADFGVSRCFHEMQSR-AITVNIRGTLGYLAPEFCNGEI-TYQLDIYSVGVIIIEIL 470 V KI+DFG S+ +++ R A +I GT + APE GEI T + DIYS G+ + ++ Sbjct: 242 VCKISDFGCSQKLQDLRCRQASPHHIGGTYTHQAPEILKGEIATPKADIYSFGITLWQMT 301 Query: 469 TGKKGY 452 T + Y Sbjct: 302 TREVPY 307 Score = 33.5 bits (75), Expect(2) = 5e-07 Identities = 14/21 (66%), Positives = 17/21 (80%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFVGWQ 648 LH ++ILHLDLKPANI + Q Sbjct: 220 LHSQSILHLDLKPANILISEQ 240
>KYK1_DICDI (P18160) Non-receptor tyrosine kinase spore lysis A (EC 2.7.10.2)| (Tyrosine-protein kinase 1) Length = 1584 Score = 53.9 bits (128), Expect = 5e-07 Identities = 43/146 (29%), Positives = 69/146 (47%), Gaps = 14/146 (9%) Frame = -3 Query: 670 RTYLLDGNLVPK-------------IADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCN 530 R LLD N+ PK I+DFG+SR E S+ +T ++ G + Y+APE Sbjct: 1421 RNILLDHNIDPKNPVVSSRQDIKCKISDFGLSRLKKEQASQ-MTQSV-GCIPYMAPEVFK 1478 Query: 529 GEITYQL-DIYSVGVIIIEILTGKKGYLAVDNVVESWSNKLEKSQSDVQLKQVRICAEIG 353 G+ + D+YS G+++ E+LT + + + + E + + L EI Sbjct: 1479 GDSNSEKSDVYSYGMVLFELLTSDEPQQDMKPMKMAHLAAYESYRPPIPLTTSSKWKEIL 1538 Query: 352 IECTDFNPAKRPGTKNIIDRLVSLDE 275 +C D NP RP K II L +++ Sbjct: 1539 TQCWDSNPDSRPTFKQIIVHLKEMED 1564
>NORK_PEA (Q8LKZ1) Nodulation receptor kinase precursor (EC 2.7.11.1)| Length = 924 Score = 53.9 bits (128), Expect = 5e-07 Identities = 24/69 (34%), Positives = 47/69 (68%), Gaps = 1/69 (1%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFC-NGEITYQLDIYSVGVI 485 LLD ++ K+ADFG S+ + +++ +RGT GYL PE+ +++ + D++S GV+ Sbjct: 728 LLDHSMCAKVADFGFSKYAPQEGDSYVSLEVRGTAGYLDPEYYKTQQLSEKSDVFSFGVV 787 Query: 484 IIEILTGKK 458 ++EI++G++ Sbjct: 788 LLEIVSGRE 796
>NORK_MEDTR (Q8L4H4) Nodulation receptor kinase precursor (EC 2.7.11.1) (Does| not make infections protein 2) (Symbiosis receptor-like kinase) (MtSYMRK) Length = 925 Score = 53.9 bits (128), Expect = 5e-07 Identities = 24/69 (34%), Positives = 47/69 (68%), Gaps = 1/69 (1%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFC-NGEITYQLDIYSVGVI 485 LLD ++ K+ADFG S+ + +++ +RGT GYL PE+ +++ + D++S GV+ Sbjct: 729 LLDQSMCAKVADFGFSKYAPQEGDSYVSLEVRGTAGYLDPEYYKTQQLSEKSDVFSFGVV 788 Query: 484 IIEILTGKK 458 ++EI++G++ Sbjct: 789 LLEIVSGRE 797
>HT1_ARATH (Q2MHE4) Serine/threonine-protein kinase HT1 (EC 2.7.11.1) (High| leaf temperature protein 1) Length = 390 Score = 51.2 bits (121), Expect(2) = 6e-07 Identities = 44/168 (26%), Positives = 76/168 (45%), Gaps = 1/168 (0%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGE-ITYQLDIYSVGVI 485 LL+ + K+ADFG S C E Q R N+ GT ++APE + T ++D+YS G++ Sbjct: 219 LLNDEMRVKVADFGTS-CL-ETQCREAKGNM-GTYRWMAPEMIKEKPYTRKVDVYSFGIV 275 Query: 484 IIEILTGKKGYLAVDNVVESWSNKLEKSQSDVQLKQVRICAEIGIECTDFNPAKRPGTKN 305 + E+ T + + V +++ + + + A + C NP+KRP N Sbjct: 276 LWELTTALLPFQGMTPVQAAFAVAEKNERPPLPASCQPALAHLIKRCWSENPSKRPDFSN 335 Query: 304 IIDRLVSLDETDSMGGYIETSAVTSQQAENALEELHQARPKVPGEISS 161 I+ L DE G + + A ++ + L+ L + SS Sbjct: 336 IVAVLEKYDECVKEGLPLTSHASLTKTKKAILDHLKGCVTSISSPFSS 383 Score = 21.9 bits (45), Expect(2) = 6e-07 Identities = 7/18 (38%), Positives = 12/18 (66%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 LH + ++H DLK N+ + Sbjct: 203 LHSQGVIHRDLKSNNLLL 220
>APK1A_ARATH (Q06548) Protein kinase APK1A, chloroplast precursor (EC 2.7.11.1)| Length = 410 Score = 53.5 bits (127), Expect = 6e-07 Identities = 41/160 (25%), Positives = 77/160 (48%), Gaps = 22/160 (13%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEF-CNGEITYQLDIYSVGVI 485 LLD K++DFG+++ ++ + GT GY APE+ G +T + D+YS GV+ Sbjct: 210 LLDSEYNAKLSDFGLAKDGPIGDKSHVSTRVMGTHGYAAPEYLATGHLTTKSDVYSFGVV 269 Query: 484 IIEILTGKKGYLAVD--------NVVESWS-----NKLE-------KSQSDVQLKQVRIC 365 ++E+L+G++ AVD N+VE W+ NK + + Q +++ Sbjct: 270 LLELLSGRR---AVDKNRPSGERNLVE-WAKPYLVNKRKIFRVIDNRLQDQYSMEEACKV 325 Query: 364 AEIGIECTDFNPAKRPGTKNIIDRLVSLDETD-SMGGYIE 248 A + + C RP ++ L + + ++GG ++ Sbjct: 326 ATLSLRCLTTEIKLRPNMSEVVSHLEHIQSLNAAIGGNMD 365
>MLTK_HUMAN (Q9NYL2) Mitogen-activated protein kinase kinase kinase MLT (EC| 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper-and sterile alpha motif-containing kinase) (Sterile alpha motif- and leucine zipper-containing kinase Length = 800 Score = 53.5 bits (127), Expect = 6e-07 Identities = 43/162 (26%), Positives = 74/162 (45%), Gaps = 5/162 (3%) Frame = -3 Query: 670 RTYLLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNG-EITYQLDIYSV 494 R ++ + V KI DFG SR FH + +++ GT ++APE ++ D YS Sbjct: 137 RNVVIAADGVLKICDFGASR-FHNHTTH---MSLVGTFPWMAPEVIQSLPVSETCDTYSY 192 Query: 493 GVIIIEILTGKKGYLAVDNVVESWSNKLEKSQSDVQLKQVRICAEIGIECTDFNPAKRPG 314 GV++ E+LT + + ++ + +W + + + R AE+ +C + + KRP Sbjct: 193 GVVLWEMLTREVPFKGLEGLQVAWLVVEKNERLTIPSSCPRSFAELLHQCWEADAKKRPS 252 Query: 313 TKNIIDRLVSLDE----TDSMGGYIETSAVTSQQAENALEEL 200 K II L S+ D ++ A + E LE L Sbjct: 253 FKQIISILESMSNDTSLPDKCNSFLHNKAEWRCEIEATLERL 294
>MLTK_MOUSE (Q9ESL4) Mitogen-activated protein kinase kinase kinase MLT (EC| 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper-and sterile alpha motif kinase ZAK) (Sterile alpha motif- and leucine zipper-containing kinase AZK) ( Length = 802 Score = 53.5 bits (127), Expect = 6e-07 Identities = 43/162 (26%), Positives = 74/162 (45%), Gaps = 5/162 (3%) Frame = -3 Query: 670 RTYLLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNG-EITYQLDIYSV 494 R ++ + V KI DFG SR FH + +++ GT ++APE ++ D YS Sbjct: 137 RNVVIAADGVLKICDFGASR-FHNHTTH---MSLVGTFPWMAPEVIQSLPVSETCDTYSY 192 Query: 493 GVIIIEILTGKKGYLAVDNVVESWSNKLEKSQSDVQLKQVRICAEIGIECTDFNPAKRPG 314 GV++ E+LT + + ++ + +W + + + R AE+ +C + + KRP Sbjct: 193 GVVLWEMLTREVPFKGLEGLQVAWLVVEKNERLTIPSSCPRSFAELLHQCWEADAKKRPS 252 Query: 313 TKNIIDRLVSLDE----TDSMGGYIETSAVTSQQAENALEEL 200 K II L S+ D ++ A + E LE L Sbjct: 253 FKQIISILESMSNDTNLPDQCNSFLHNKAEWRCEIEATLERL 294
>YR831_MIMIV (Q7T6Y2) Putative serine/threonine-protein kinase/receptor R831| precursor (EC 2.7.11.1) Length = 1624 Score = 51.2 bits (121), Expect(2) = 7e-07 Identities = 28/73 (38%), Positives = 45/73 (61%), Gaps = 3/73 (4%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNG--EITYQL-DIYSVG 491 LLD K++DFG+++ E+ + NI GT+ ++APE N E+ Y L D+YS G Sbjct: 915 LLDSKWNVKVSDFGLTKVKSELDKKKTNDNIIGTIHWIAPEILNDSTEVDYILADVYSFG 974 Query: 490 VIIIEILTGKKGY 452 +I+ E+LT ++ Y Sbjct: 975 IILWELLTREQPY 987 Score = 44.3 bits (103), Expect(2) = 4e-06 Identities = 37/130 (28%), Positives = 65/130 (50%), Gaps = 1/130 (0%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGE-ITYQLDIYSVGVI 485 L+D + KIADFG +R ++ T+ GT + APE GE + D++S GV+ Sbjct: 1494 LVDEHFNVKIADFGFAR----IKEDNTTMTRCGTPCWTAPEVIRGEKYCEKADVFSFGVV 1549 Query: 484 IIEILTGKKGYLAVDNVVESWSNKLEKSQSDVQLKQVRICAEIGIECTDFNPAKRPGTKN 305 + E+LTGK+ + A N ++ + LE + + A++ +C KRP Sbjct: 1550 MWEVLTGKEPF-AECNFMKVSLDILEGGRPIIPSDCPHEFAKLIKKCWHAKAHKRPTMTE 1608 Query: 304 IIDRLVSLDE 275 ++ +L+ + E Sbjct: 1609 VVQQLMLITE 1618 Score = 25.8 bits (55), Expect(2) = 4e-06 Identities = 13/24 (54%), Positives = 15/24 (62%), Gaps = 2/24 (8%) Frame = -2 Query: 710 LHQRN--ILHLDLKPANIFVGWQF 645 LH N I+H D+KPANI V F Sbjct: 1476 LHSSNPMIVHRDIKPANILVDEHF 1499 Score = 21.6 bits (44), Expect(2) = 7e-07 Identities = 8/18 (44%), Positives = 11/18 (61%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 LH I+H DLK N+ + Sbjct: 899 LHSSGIVHRDLKSLNLLL 916
>MOS_MSVMT (P32593) Serine/threonine-protein kinase transforming protein mos| (EC 2.7.11.1) Length = 354 Score = 39.3 bits (90), Expect(2) = 8e-07 Identities = 26/66 (39%), Positives = 38/66 (57%), Gaps = 2/66 (3%) Frame = -3 Query: 643 VPKIADFGVSRCFHEMQSR-AITVNIRGTLGYLAPEFCNGEI-TYQLDIYSVGVIIIEIL 470 V KI+DFG S+ ++ R A +I GT + APE GEI T + DIYS G+ + ++ Sbjct: 222 VCKISDFGCSQKLQVLRGRQASPPHIGGTYTHQAPEILKGEIATPKADIYSFGITLWQMT 281 Query: 469 TGKKGY 452 T + Y Sbjct: 282 TREVPY 287 Score = 33.5 bits (75), Expect(2) = 8e-07 Identities = 14/21 (66%), Positives = 17/21 (80%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFVGWQ 648 LH ++ILHLDLKPANI + Q Sbjct: 200 LHSQSILHLDLKPANILISEQ 220
>FGFR3_HUMAN (P22607) Fibroblast growth factor receptor 3 precursor (EC 2.7.10.1)| (FGFR-3) (CD333 antigen) Length = 806 Score = 52.8 bits (125), Expect = 1e-06 Identities = 47/153 (30%), Positives = 74/153 (48%), Gaps = 5/153 (3%) Frame = -3 Query: 670 RTYLLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEI-TYQLDIYSV 494 R L+ + V KIADFG++R H + T N R + ++APE + T+Q D++S Sbjct: 621 RNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSF 680 Query: 493 GVIIIEILT-GKKGYLAVDNVVESWSNKLEKSQSDVQLKQVRICAEIGIECTDFNPAKRP 317 GV++ EI T G Y + V E + E + D I EC P++RP Sbjct: 681 GVLLWEIFTLGGSPYPGIP-VEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRP 739 Query: 316 GTKNII---DRLVSLDETDSMGGYIETSAVTSQ 227 K ++ DR++++ TD Y++ SA Q Sbjct: 740 TFKQLVEDLDRVLTVTSTDE---YLDLSAPFEQ 769
>NIM1_NEUCR (P48479) G2-specific protein kinase nim-1 (EC 2.7.11.1)| Length = 779 Score = 45.4 bits (106), Expect(2) = 1e-06 Identities = 38/133 (28%), Positives = 58/133 (43%), Gaps = 7/133 (5%) Frame = -3 Query: 673 QRTYLLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGE-ITYQLDIYS 497 + +L + N V K+ DFG+S+ MQS GT Y++PE C E T + DI+S Sbjct: 165 ENVFLGEDNSV-KLGDFGLSKV---MQSHDFASTYVGTPFYMSPEICAAEKYTLKSDIWS 220 Query: 496 VGVIIIEI------LTGKKGYLAVDNVVESWSNKLEKSQSDVQLKQVRICAEIGIECTDF 335 +G II E+ K Y V + E L S ++ C + Sbjct: 221 LGCIIYELCAREPPFNAKTHYQLVQKIKEGKIAPLPSVYSGELFATIKDCLRV------- 273 Query: 334 NPAKRPGTKNIID 296 NP +RP T +++ Sbjct: 274 NPDRRPDTATLLN 286 Score = 26.6 bits (57), Expect(2) = 1e-06 Identities = 10/14 (71%), Positives = 12/14 (85%) Frame = -2 Query: 695 ILHLDLKPANIFVG 654 ILH DLKP N+F+G Sbjct: 157 ILHRDLKPENVFLG 170
>MOS_MOUSE (P00536) Proto-oncogene serine/threonine-protein kinase mos (EC| 2.7.11.1) (c-mos) (Oocyte maturation factor mos) Length = 390 Score = 38.5 bits (88), Expect(2) = 1e-06 Identities = 26/66 (39%), Positives = 38/66 (57%), Gaps = 2/66 (3%) Frame = -3 Query: 643 VPKIADFGVSRCFHEMQSR-AITVNIRGTLGYLAPEFCNGEI-TYQLDIYSVGVIIIEIL 470 V KI+DFG S+ ++ R A +I GT + APE GEI T + DIYS G+ + ++ Sbjct: 258 VCKISDFGCSQKLQVLRCRQASPHHIGGTYTHQAPEILKGEIATPKADIYSFGITLWQMT 317 Query: 469 TGKKGY 452 T + Y Sbjct: 318 TREVPY 323 Score = 33.5 bits (75), Expect(2) = 1e-06 Identities = 14/21 (66%), Positives = 17/21 (80%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFVGWQ 648 LH ++ILHLDLKPANI + Q Sbjct: 236 LHSQSILHLDLKPANILISEQ 256
>M3KL4_HUMAN (Q5TCX8) Mitogen-activated protein kinase kinase kinase (EC| 2.7.11.25) (Mixed lineage kinase 4) Length = 1036 Score = 52.4 bits (124), Expect = 1e-06 Identities = 34/125 (27%), Positives = 63/125 (50%), Gaps = 1/125 (0%) Frame = -3 Query: 649 NLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEITYQ-LDIYSVGVIIIEI 473 N KI DFG++R +H R ++ GT ++APE + + DI+S GV++ E+ Sbjct: 282 NKTLKITDFGLAREWH----RTTKMSTAGTYAWMAPEVIKSSLFSKGSDIWSYGVLLWEL 337 Query: 472 LTGKKGYLAVDNVVESWSNKLEKSQSDVQLKQVRICAEIGIECTDFNPAKRPGTKNIIDR 293 LTG+ Y +D + ++ + K + A++ EC +P RP I+++ Sbjct: 338 LTGEVPYRGIDGLAVAYGVAVNKLTLPIPSTCPEPFAKLMKECWQQDPHIRPSFALILEQ 397 Query: 292 LVSLD 278 L +++ Sbjct: 398 LTAIE 402
>PKNB_LACLA (Q9CEF5) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 627 Score = 46.2 bits (108), Expect(2) = 2e-06 Identities = 24/60 (40%), Positives = 38/60 (63%), Gaps = 1/60 (1%) Frame = -3 Query: 637 KIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGE-ITYQLDIYSVGVIIIEILTGK 461 K+ DFG+++ E S T + G++ YL+PE G T Q DIY++G+I+ E+LTG+ Sbjct: 151 KVTDFGIAKALSET-SLTQTNTMFGSVHYLSPEQARGSNATVQSDIYAIGIILFELLTGQ 209 Score = 25.4 bits (54), Expect(2) = 2e-06 Identities = 9/17 (52%), Positives = 11/17 (64%) Frame = -2 Query: 707 HQRNILHLDLKPANIFV 657 H I+H DLKP N+ V Sbjct: 128 HSHGIIHRDLKPQNVLV 144
>PKNB_MYCTU (P0A5S4) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 626 Score = 43.1 bits (100), Expect(2) = 2e-06 Identities = 22/61 (36%), Positives = 37/61 (60%), Gaps = 2/61 (3%) Frame = -3 Query: 637 KIADFGVSRCFHEM-QSRAITVNIRGTLGYLAPEFCNGE-ITYQLDIYSVGVIIIEILTG 464 K+ DFG++R + S T + GT YL+PE G+ + + D+YS+G ++ E+LTG Sbjct: 153 KVMDFGIARAIADSGNSVTQTAAVIGTAQYLSPEQARGDSVDARSDVYSLGCVLYEVLTG 212 Query: 463 K 461 + Sbjct: 213 E 213 Score = 28.1 bits (61), Expect(2) = 2e-06 Identities = 10/17 (58%), Positives = 13/17 (76%) Frame = -2 Query: 707 HQRNILHLDLKPANIFV 657 HQ I+H D+KPANI + Sbjct: 130 HQNGIIHRDVKPANIMI 146
>PKNB_MYCBO (P0A5S5) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 626 Score = 43.1 bits (100), Expect(2) = 2e-06 Identities = 22/61 (36%), Positives = 37/61 (60%), Gaps = 2/61 (3%) Frame = -3 Query: 637 KIADFGVSRCFHEM-QSRAITVNIRGTLGYLAPEFCNGE-ITYQLDIYSVGVIIIEILTG 464 K+ DFG++R + S T + GT YL+PE G+ + + D+YS+G ++ E+LTG Sbjct: 153 KVMDFGIARAIADSGNSVTQTAAVIGTAQYLSPEQARGDSVDARSDVYSLGCVLYEVLTG 212 Query: 463 K 461 + Sbjct: 213 E 213 Score = 28.1 bits (61), Expect(2) = 2e-06 Identities = 10/17 (58%), Positives = 13/17 (76%) Frame = -2 Query: 707 HQRNILHLDLKPANIFV 657 HQ I+H D+KPANI + Sbjct: 130 HQNGIIHRDVKPANIMI 146
>MK14C_DROME (P83100) Putative mitogen-activated protein kinase 14C (EC| 2.7.11.24) (MAP kinase p38c) Length = 356 Score = 46.2 bits (108), Expect(2) = 2e-06 Identities = 27/69 (39%), Positives = 41/69 (59%), Gaps = 3/69 (4%) Frame = -3 Query: 658 LDGNLVPKIADFGVSR-CFHEMQSRAITVNIRGTLGYLAPE--FCNGEITYQLDIYSVGV 488 ++GN +I DFG+SR C +M GT+ YLAPE F G+ T +D++SVG Sbjct: 155 VNGNSEVRILDFGLSRMCADKMTDHV------GTMWYLAPEIIFLRGQYTKAIDVWSVGC 208 Query: 487 IIIEILTGK 461 I+ E++T + Sbjct: 209 ILAELITDR 217 Score = 25.0 bits (53), Expect(2) = 2e-06 Identities = 9/18 (50%), Positives = 12/18 (66%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 +H ++H DLKP NI V Sbjct: 138 IHSAGVVHRDLKPCNIAV 155
>CEK2_CHICK (P18460) Tyrosine kinase receptor CEK2 precursor (EC 2.7.10.1)| Length = 806 Score = 51.6 bits (122), Expect = 2e-06 Identities = 49/163 (30%), Positives = 79/163 (48%), Gaps = 5/163 (3%) Frame = -3 Query: 670 RTYLLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEI-TYQLDIYSV 494 R L+ + V KIADFG++R H + T N R + ++APE + T+Q D++S Sbjct: 615 RNVLVTEDNVMKIADFGLARDVHNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSF 674 Query: 493 GVIIIEILT-GKKGYLAVDNVVESWSNKLEKSQSDVQLKQVRICAEIGIECTDFNPAKRP 317 GV++ EI T G Y + V E + E + D I EC P++RP Sbjct: 675 GVLLWEIFTLGGSPYPGIP-VEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAVPSQRP 733 Query: 316 GTKNII---DRLVSLDETDSMGGYIETSAVTSQQAENALEELH 197 K ++ DR++++ TD Y++ S V +Q A ++ H Sbjct: 734 TFKQLVEDLDRVLTMTSTDE---YLDLS-VPFEQYSPAGQDTH 772
>FGFR3_MOUSE (Q61851) Fibroblast growth factor receptor 3 precursor (EC 2.7.10.1)| (FGFR-3) (Heparin-binding growth factor receptor) Length = 801 Score = 51.2 bits (121), Expect = 3e-06 Identities = 46/154 (29%), Positives = 73/154 (47%), Gaps = 6/154 (3%) Frame = -3 Query: 670 RTYLLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEI-TYQLDIYSV 494 R L+ + V KIADFG++R H + T N R + ++APE + T+Q D++S Sbjct: 615 RNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSF 674 Query: 493 GVIIIEILT--GKKGYLAVDNVVESWSNKLEKSQSDVQLKQVRICAEIGIECTDFNPAKR 320 GV++ EI T G Y + V E + E + D I EC P++R Sbjct: 675 GVLLWEIFTPGGPSPYPGIP-VEELFKLLKEGHRMDKPASCTHDLYMIMRECWHAVPSQR 733 Query: 319 PGTKNII---DRLVSLDETDSMGGYIETSAVTSQ 227 P K ++ DR++++ TD Y++ S Q Sbjct: 734 PTFKQLVEDLDRILTVTSTDE---YLDLSVPFEQ 764
>M3K10_HUMAN (Q02779) Mitogen-activated protein kinase kinase kinase 10 (EC| 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST) Length = 954 Score = 51.2 bits (121), Expect = 3e-06 Identities = 34/125 (27%), Positives = 64/125 (51%), Gaps = 1/125 (0%) Frame = -3 Query: 643 VPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEI-TYQLDIYSVGVIIIEILT 467 V KI DFG++R +H + ++ GT ++APE + + D++S GV++ E+LT Sbjct: 243 VLKITDFGLAREWH----KTTKMSAAGTYAWMAPEVIRLSLFSKSSDVWSFGVLLWELLT 298 Query: 466 GKKGYLAVDNVVESWSNKLEKSQSDVQLKQVRICAEIGIECTDFNPAKRPGTKNIIDRLV 287 G+ Y +D + ++ + K + A + EC D +P RP +I+ RL Sbjct: 299 GEVPYREIDALAVAYGVAMNKLTLPIPSTCPEPFARLLEECWDPDPHGRPDFGSILKRLE 358 Query: 286 SLDET 272 ++++ Sbjct: 359 VIEQS 363
>IPL1_CANAL (Q59S66) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 530 Score = 39.3 bits (90), Expect(2) = 5e-06 Identities = 25/106 (23%), Positives = 58/106 (54%), Gaps = 3/106 (2%) Frame = -3 Query: 604 HEMQSRAITVNIRGTLGYLAPEFCNGEI-TYQLDIYSVGVIIIEILTGKKGYLAVD-NVV 431 H+ + + + I GTL YL PE + + +DI+++G++ E+L GK + A++ N+ Sbjct: 412 HQKKQKQKRLTICGTLDYLPPEMIESKSHDFSVDIWALGILCYELLVGKPPFEAINRNIT 471 Query: 430 ESWSNKLE-KSQSDVQLKQVRICAEIGIECTDFNPAKRPGTKNIID 296 K++ K S++ + + + +++ ++ +P KR K +++ Sbjct: 472 YEKIAKVDIKYPSNLDVDAIDLISKLVVK----DPNKRLSLKEVLN 513 Score = 30.8 bits (68), Expect(2) = 5e-06 Identities = 12/18 (66%), Positives = 14/18 (77%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 LHQR I+H DLKP NI + Sbjct: 358 LHQRGIIHRDLKPENIMI 375
>PKN1_THETN (Q8R9T6) Probable serine/threonine-protein kinase Sps1 (EC| 2.7.11.1) Length = 625 Score = 44.3 bits (103), Expect(2) = 6e-06 Identities = 24/62 (38%), Positives = 38/62 (61%), Gaps = 1/62 (1%) Frame = -3 Query: 643 VPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEITYQ-LDIYSVGVIIIEILT 467 V K+ DFG++R + + T ++ GT Y +PE G I + DIYS+G+++ E+LT Sbjct: 147 VVKVTDFGIARAANGA-TITYTGDVIGTAYYFSPEQAKGSIVDERTDIYSLGIVLFEMLT 205 Query: 466 GK 461 GK Sbjct: 206 GK 207 Score = 25.4 bits (54), Expect(2) = 6e-06 Identities = 9/17 (52%), Positives = 12/17 (70%) Frame = -2 Query: 707 HQRNILHLDLKPANIFV 657 H+ I+H D+KP NI V Sbjct: 126 HKNKIIHRDIKPQNILV 142
>MIL_AVIMH (P00531) Serine/threonine-protein kinase transforming protein mil| (EC 2.7.11.1) Length = 380 Score = 42.7 bits (99), Expect(2) = 6e-06 Identities = 22/78 (28%), Positives = 40/78 (51%), Gaps = 4/78 (5%) Frame = -3 Query: 658 LDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFC----NGEITYQLDIYSVG 491 L G L KI DFG++ G++ ++APE + ++Q D+YS G Sbjct: 209 LHGGLTVKIGDFGLATVKSRWSGSQQVEQPTGSILWMAPEVIRMQDSNPFSFQSDVYSYG 268 Query: 490 VIIIEILTGKKGYLAVDN 437 +++ E++TG+ Y ++N Sbjct: 269 IVLYELMTGELPYSHINN 286 Score = 26.9 bits (58), Expect(2) = 6e-06 Identities = 10/18 (55%), Positives = 14/18 (77%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 LH +NI+H D+K NIF+ Sbjct: 192 LHAKNIIHRDMKSNNIFL 209
>CDC22_XENLA (P24033) Cell division control protein 2 homolog 2 (EC 2.7.11.22)| (EC 2.7.11.23) (p34 protein kinase 2) Length = 302 Score = 42.7 bits (99), Expect(2) = 6e-06 Identities = 29/69 (42%), Positives = 39/69 (56%), Gaps = 2/69 (2%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEITYQ--LDIYSVGV 488 L+D V K+ADFG++R F + R T + TL Y APE G + Y +D++SVG Sbjct: 135 LIDNKGVIKLADFGLARAF-GIPVRVYTHEV-VTLWYRAPEVLLGSVRYSTPVDVWSVGT 192 Query: 487 IIIEILTGK 461 I EI T K Sbjct: 193 IFAEIATKK 201 Score = 26.9 bits (58), Expect(2) = 6e-06 Identities = 9/17 (52%), Positives = 12/17 (70%) Frame = -2 Query: 707 HQRNILHLDLKPANIFV 657 H R +LH DLKP N+ + Sbjct: 120 HSRGVLHRDLKPQNLLI 136
>M3LK7_DROME (P83104) Putative mitogen-activated protein kinase kinase kinase| 7-like (EC 2.7.11.25) Length = 393 Score = 50.1 bits (118), Expect = 7e-06 Identities = 36/119 (30%), Positives = 61/119 (51%), Gaps = 7/119 (5%) Frame = -3 Query: 637 KIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNG-EITYQLDIYSVGVIIIEILTGK 461 KI DFG++ ++ +++GTL Y+APE + T + D+YS G+++ E++T + Sbjct: 149 KICDFGLATDMSNNKT-----DMQGTLRYMAPEAIKHLKYTAKCDVYSFGIMLWELMTRQ 203 Query: 460 KGYLAVDNVVESWS-NKLEKSQSDVQLKQVRICAEIGIE-----CTDFNPAKRPGTKNI 302 Y ++N ++ K S + ++ VR GI+ C D NP KRP K I Sbjct: 204 LPYSHLENPNSQYAIMKAISSGEKLPMEAVRSDCPEGIKQLMECCMDINPEKRPSMKEI 262
>M3K11_HUMAN (Q16584) Mitogen-activated protein kinase kinase kinase 11 (EC| 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline-rich kinase) Length = 847 Score = 50.1 bits (118), Expect = 7e-06 Identities = 31/121 (25%), Positives = 62/121 (51%), Gaps = 1/121 (0%) Frame = -3 Query: 637 KIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGE-ITYQLDIYSVGVIIIEILTGK 461 KI DFG++R +H + ++ GT ++APE + D++S GV++ E+LTG+ Sbjct: 264 KITDFGLAREWH----KTTQMSAAGTYAWMAPEVIKASTFSKGSDVWSFGVLLWELLTGE 319 Query: 460 KGYLAVDNVVESWSNKLEKSQSDVQLKQVRICAEIGIECTDFNPAKRPGTKNIIDRLVSL 281 Y +D + ++ + K + A++ +C +P +RP +I+ +L +L Sbjct: 320 VPYRGIDCLAVAYGVAVNKLTLPIPSTCPEPFAQLMADCWAQDPHRRPDFASILQQLEAL 379 Query: 280 D 278 + Sbjct: 380 E 380
>CHK1_CAEEL (Q9N3Z3) Serine/threonine-protein kinase chk-1 (EC 2.7.11.1)| Length = 503 Score = 45.8 bits (107), Expect(2) = 8e-06 Identities = 27/93 (29%), Positives = 49/93 (52%), Gaps = 3/93 (3%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEITYQ---LDIYSVG 491 LL G V KI+DFG++ + + GT+ Y APE C G+ Y+ +D++S G Sbjct: 157 LLTGTHVLKISDFGMATLYRNKGEERLLDLSCGTIPYAAPELCAGK-KYRGPPVDVWSSG 215 Query: 490 VIIIEILTGKKGYLAVDNVVESWSNKLEKSQSD 392 +++I +LTG+ + + +S+ + + D Sbjct: 216 IVLIAMLTGELPWDRASDASQSYMGWISNTSLD 248 Score = 23.5 bits (49), Expect(2) = 8e-06 Identities = 6/18 (33%), Positives = 13/18 (72%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 +H +++H D+KP N+ + Sbjct: 141 IHDNDVVHRDIKPENLLL 158
>CDC21_XENLA (P35567) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| (EC 2.7.11.23) (p34 protein kinase 1) Length = 302 Score = 42.4 bits (98), Expect(2) = 8e-06 Identities = 28/69 (40%), Positives = 39/69 (56%), Gaps = 2/69 (2%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEITYQ--LDIYSVGV 488 L+D V K+ADFG++R F + R T + TL Y APE G + Y +D++S+G Sbjct: 135 LIDSKGVIKLADFGLARAF-GIPVRVYTHEV-VTLWYRAPEVLLGSVRYSTPVDVWSIGT 192 Query: 487 IIIEILTGK 461 I EI T K Sbjct: 193 IFAEIATKK 201 Score = 26.9 bits (58), Expect(2) = 8e-06 Identities = 9/17 (52%), Positives = 12/17 (70%) Frame = -2 Query: 707 HQRNILHLDLKPANIFV 657 H R +LH DLKP N+ + Sbjct: 120 HSRRVLHRDLKPQNLLI 136
>CLV1_ARATH (Q9SYQ8) Receptor protein kinase CLAVATA1 precursor (EC 2.7.11.1)| Length = 980 Score = 49.7 bits (117), Expect = 9e-06 Identities = 23/69 (33%), Positives = 43/69 (62%), Gaps = 1/69 (1%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFC-NGEITYQLDIYSVGVI 485 LLD + +ADFG+++ + + +I G+ GY+APE+ ++ + D+YS GV+ Sbjct: 824 LLDSDFEAHVADFGLAKFLVDGAASECMSSIAGSYGYIAPEYAYTLKVDEKSDVYSFGVV 883 Query: 484 IIEILTGKK 458 ++E++ GKK Sbjct: 884 LLELIAGKK 892
>IRAK1_MOUSE (Q62406) Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1)| (IRAK-1) (IRAK) (Pelle-like protein kinase) (mPLK) Length = 710 Score = 49.7 bits (117), Expect = 9e-06 Identities = 28/76 (36%), Positives = 42/76 (55%), Gaps = 8/76 (10%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFH-------EMQSRAITVNIRGTLGYLAPEFC-NGEITYQLD 506 LLD L+PK+ DFG++R + + A T +RGTL YL E+ G + D Sbjct: 347 LLDERLMPKLGDFGLARFSRFAGAKASQSSTVARTSTVRGTLAYLPEEYIKTGRLAVDTD 406 Query: 505 IYSVGVIIIEILTGKK 458 +S GV+I+E L G++ Sbjct: 407 TFSFGVVILETLAGQR 422
>IKKB_RAT (Q9QY78) Inhibitor of nuclear factor kappa B kinase beta subunit| (EC 2.7.11.1) (I-kappa-B-kinase beta) (IkBKB) (IKK-beta) (IKK-B) (I-kappa-B kinase 2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB) Length = 757 Score = 42.4 bits (98), Expect(2) = 1e-05 Identities = 27/91 (29%), Positives = 47/91 (51%), Gaps = 1/91 (1%) Frame = -3 Query: 646 LVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGE-ITYQLDIYSVGVIIIEIL 470 L+ KI D G ++ E+ ++ + GTL YLAPE + T +D +S G + E + Sbjct: 160 LIHKIIDLGYAK---ELDQGSLCTSFVGTLQYLAPELLEQQKYTVTVDYWSFGTLAFECI 216 Query: 469 TGKKGYLAVDNVVESWSNKLEKSQSDVQLKQ 377 TG + +L V+ S +KS+ D+ + + Sbjct: 217 TGFRPFLPNWQPVQWHSKVRQKSEVDIVVSE 247 Score = 26.6 bits (57), Expect(2) = 1e-05 Identities = 10/16 (62%), Positives = 12/16 (75%) Frame = -2 Query: 710 LHQRNILHLDLKPANI 663 LH+ I+H DLKP NI Sbjct: 136 LHENRIIHRDLKPENI 151
>IKKB_MOUSE (O88351) Inhibitor of nuclear factor kappa B kinase beta subunit| (EC 2.7.11.10) (I-kappa-B-kinase beta) (IkBKB) (IKK-beta) (IKK-B) (I-kappa-B kinase 2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB) Length = 757 Score = 42.4 bits (98), Expect(2) = 1e-05 Identities = 27/91 (29%), Positives = 47/91 (51%), Gaps = 1/91 (1%) Frame = -3 Query: 646 LVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGE-ITYQLDIYSVGVIIIEIL 470 L+ KI D G ++ E+ ++ + GTL YLAPE + T +D +S G + E + Sbjct: 160 LIHKIIDLGYAK---ELDQGSLCTSFVGTLQYLAPELLEQQKYTVTVDYWSFGTLAFECI 216 Query: 469 TGKKGYLAVDNVVESWSNKLEKSQSDVQLKQ 377 TG + +L V+ S +KS+ D+ + + Sbjct: 217 TGFRPFLPNWQPVQWHSKVRQKSEVDIVVSE 247 Score = 26.6 bits (57), Expect(2) = 1e-05 Identities = 10/16 (62%), Positives = 12/16 (75%) Frame = -2 Query: 710 LHQRNILHLDLKPANI 663 LH+ I+H DLKP NI Sbjct: 136 LHENRIIHRDLKPENI 151
>IKKB_HUMAN (O14920) Inhibitor of nuclear factor kappa B kinase beta subunit| (EC 2.7.11.10) (I-kappa-B-kinase beta) (IkBKB) (IKK-beta) (IKK-B) (I-kappa-B kinase 2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB) Length = 756 Score = 42.4 bits (98), Expect(2) = 1e-05 Identities = 27/91 (29%), Positives = 47/91 (51%), Gaps = 1/91 (1%) Frame = -3 Query: 646 LVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGE-ITYQLDIYSVGVIIIEIL 470 L+ KI D G ++ E+ ++ + GTL YLAPE + T +D +S G + E + Sbjct: 160 LIHKIIDLGYAK---ELDQGSLCTSFVGTLQYLAPELLEQQKYTVTVDYWSFGTLAFECI 216 Query: 469 TGKKGYLAVDNVVESWSNKLEKSQSDVQLKQ 377 TG + +L V+ S +KS+ D+ + + Sbjct: 217 TGFRPFLPNWQPVQWHSKVRQKSEVDIVVSE 247 Score = 26.6 bits (57), Expect(2) = 1e-05 Identities = 10/16 (62%), Positives = 12/16 (75%) Frame = -2 Query: 710 LHQRNILHLDLKPANI 663 LH+ I+H DLKP NI Sbjct: 136 LHENRIIHRDLKPENI 151
>PK1_STRTO (Q9KIG4) Serine/threonine-protein kinase PK-1 (EC 2.7.11.1)| (stoPK-1) Length = 641 Score = 44.3 bits (103), Expect(2) = 1e-05 Identities = 24/61 (39%), Positives = 39/61 (63%), Gaps = 1/61 (1%) Frame = -3 Query: 637 KIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFC-NGEITYQLDIYSVGVIIIEILTGK 461 K+ADFG+ R + + TV GT+ YLAPE +G ++D+Y+ G+++ E+LTG+ Sbjct: 156 KVADFGLVRAVDSVTNTTGTV--LGTVSYLAPEQIEHGTADPRVDVYACGILLYEMLTGE 213 Query: 460 K 458 K Sbjct: 214 K 214 Score = 24.6 bits (52), Expect(2) = 1e-05 Identities = 7/18 (38%), Positives = 12/18 (66%) Frame = -2 Query: 707 HQRNILHLDLKPANIFVG 654 H+ +H D+KP N+ +G Sbjct: 133 HRAGFVHRDMKPENVLIG 150
>IPL1_YEAST (P38991) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) (Increase-in-ploidy protein 1) Length = 367 Score = 37.4 bits (85), Expect(2) = 1e-05 Identities = 25/67 (37%), Positives = 39/67 (58%), Gaps = 1/67 (1%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNG-EITYQLDIYSVGVI 485 L+ N V K+ DFG S + ++R TV GT+ YL+PE E + +D +++GV+ Sbjct: 234 LIGFNNVIKLTDFGWS-IINPPENRRKTVC--GTIDYLSPEMVESREYDHTIDAWALGVL 290 Query: 484 IIEILTG 464 E+LTG Sbjct: 291 AFELLTG 297 Score = 31.6 bits (70), Expect(2) = 1e-05 Identities = 10/20 (50%), Positives = 17/20 (85%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFVGW 651 +H++NI+H D+KP NI +G+ Sbjct: 218 MHKKNIIHRDIKPENILIGF 237
>ARK1_SCHPO (O59790) Serine/threonine-protein kinase ark1 (EC 2.7.11.1)| (Aurora-related kinase 1) Length = 355 Score = 40.0 bits (92), Expect(2) = 1e-05 Identities = 27/66 (40%), Positives = 39/66 (59%), Gaps = 1/66 (1%) Frame = -3 Query: 658 LDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNG-EITYQLDIYSVGVII 482 +DG + K++DFG S H +R T + GTL YL PE G E T ++D++S+GV+ Sbjct: 222 IDGEI--KLSDFGWS--VHAPSNRRTT--LCGTLDYLPPEMVEGKEHTEKVDLWSLGVLT 275 Query: 481 IEILTG 464 E L G Sbjct: 276 YEFLVG 281 Score = 28.9 bits (63), Expect(2) = 1e-05 Identities = 9/19 (47%), Positives = 16/19 (84%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFVG 654 LH+++++H D+KP NI +G Sbjct: 203 LHKKHVIHRDIKPENILLG 221
>MKH1_SCHPO (Q10407) MAP kinase kinase kinase mkh1 (EC 2.7.11.25)| Length = 1116 Score = 45.1 bits (105), Expect(2) = 1e-05 Identities = 27/129 (20%), Positives = 67/129 (51%), Gaps = 7/129 (5%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGE---ITYQLDIYSVG 491 L+D + V KI+DFG+S+ + ++++G++ ++APE + + + ++D++S+G Sbjct: 962 LIDFDGVCKISDFGISKHSDNVYDNDANLSMQGSIFWMAPEVIHNDHQGYSAKVDVWSLG 1021 Query: 490 VIIIEILTGKKGYLAVDNVVESWSNKLEKSQSDVQLKQVRICAEIGIE----CTDFNPAK 323 +++E+L G++ + + + + EK + + V + I+ C N Sbjct: 1022 CVVLEMLAGRRPWSTDEAIQAMFKLGTEKKAPPIPSELVSQVSPEAIQFLNACFTVNADV 1081 Query: 322 RPGTKNIID 296 RP + +++ Sbjct: 1082 RPTAEELLN 1090 Score = 23.5 bits (49), Expect(2) = 1e-05 Identities = 8/18 (44%), Positives = 12/18 (66%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 LH + I+H DLK N+ + Sbjct: 946 LHSKGIIHRDLKADNLLI 963
>PKNB_BIFLO (Q8G6P9) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 690 Score = 42.7 bits (99), Expect(2) = 1e-05 Identities = 22/63 (34%), Positives = 37/63 (58%), Gaps = 2/63 (3%) Frame = -3 Query: 643 VPKIADFGVSRCFHEMQSRAI-TVNIRGTLGYLAPEFCNGE-ITYQLDIYSVGVIIIEIL 470 V K+ DFG++R + + + + GT YL+PE GE + + D+YS G ++ E+L Sbjct: 159 VVKVMDFGIARALDDSAATMTQSQGVVGTAQYLSPEQARGETVDMRSDLYSAGCVLYEML 218 Query: 469 TGK 461 TG+ Sbjct: 219 TGR 221 Score = 25.8 bits (55), Expect(2) = 1e-05 Identities = 9/20 (45%), Positives = 13/20 (65%) Frame = -2 Query: 707 HQRNILHLDLKPANIFVGWQ 648 H+ I+H D+KP NI + Q Sbjct: 138 HRMGIIHRDIKPGNIMISEQ 157
>PKN2_CLOPE (Q8XJL8) Probable serine/threonine protein kinase CPE1738 (EC| 2.7.11.1) Length = 685 Score = 43.9 bits (102), Expect(2) = 1e-05 Identities = 21/61 (34%), Positives = 39/61 (63%), Gaps = 1/61 (1%) Frame = -3 Query: 643 VPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEIT-YQLDIYSVGVIIIEILT 467 V K+ DFG+++ + + A T ++ G+ Y +PE G T Y+ D+YS+G+++ E++T Sbjct: 146 VVKVTDFGIAKSM-DSSTIAHTNSVMGSAHYFSPEQAKGTYTDYRTDLYSLGIVLYEMVT 204 Query: 466 G 464 G Sbjct: 205 G 205 Score = 24.6 bits (52), Expect(2) = 1e-05 Identities = 9/17 (52%), Positives = 12/17 (70%) Frame = -2 Query: 707 HQRNILHLDLKPANIFV 657 H+ I+H D+KP NI V Sbjct: 125 HKSGIIHRDVKPQNILV 141
>STK6L_XENLA (Q91819) Serine/threonine-protein kinase Eg2-like (EC 2.7.11.1)| (p46XlEg22) Length = 408 Score = 42.7 bits (99), Expect(2) = 1e-05 Identities = 30/68 (44%), Positives = 38/68 (55%), Gaps = 1/68 (1%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEI-TYQLDIYSVGVI 485 LL N KIADFG S H SR T + GTL YL PE G + ++D++S+GV+ Sbjct: 270 LLGSNGELKIADFGWS--VHAPSSRRTT--LCGTLDYLPPEMIEGRMHDEKVDLWSLGVL 325 Query: 484 IIEILTGK 461 E L GK Sbjct: 326 CYEFLVGK 333 Score = 25.8 bits (55), Expect(2) = 1e-05 Identities = 7/18 (38%), Positives = 13/18 (72%) Frame = -2 Query: 707 HQRNILHLDLKPANIFVG 654 H + ++H D+KP N+ +G Sbjct: 255 HSKKVIHRDIKPENLLLG 272
>STK6_HUMAN (O14965) Serine/threonine-protein kinase 6 (EC 2.7.11.1)| (Serine/threonine kinase 15) (Aurora/IPL1-related kinase 1) (Aurora-related kinase 1) (hARK1) (Aurora-A) (Breast-tumor-amplified kinase) Length = 403 Score = 42.7 bits (99), Expect(2) = 1e-05 Identities = 33/115 (28%), Positives = 55/115 (47%), Gaps = 1/115 (0%) Frame = -3 Query: 637 KIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEI-TYQLDIYSVGVIIIEILTGK 461 KIADFG S H SR T + GTL YL PE G + ++D++S+GV+ E L GK Sbjct: 271 KIADFGWS--VHAPSSRRTT--LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGK 326 Query: 460 KGYLAVDNVVESWSNKLEKSQSDVQLKQVRICAEIGIECTDFNPAKRPGTKNIID 296 + A N + ++ + + ++ NP++RP + +++ Sbjct: 327 PPFEA--NTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLE 379 Score = 25.8 bits (55), Expect(2) = 1e-05 Identities = 7/18 (38%), Positives = 13/18 (72%) Frame = -2 Query: 707 HQRNILHLDLKPANIFVG 654 H + ++H D+KP N+ +G Sbjct: 248 HSKRVIHRDIKPENLLLG 265
>IRAK3_MOUSE (Q8K4B2) Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1)| (IRAK-3) (IL-1 receptor-associated kinase M) (IRAK-M) Length = 609 Score = 48.9 bits (115), Expect = 2e-05 Identities = 25/73 (34%), Positives = 43/73 (58%), Gaps = 5/73 (6%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGT----LGYLAPEFCN-GEITYQLDIYS 497 LLD L PK+ DF + ++ ++ T+N+ G L Y+ E+ G ++ + D+YS Sbjct: 313 LLDDQLQPKLTDFAAAHFRPNLEQQSSTINMTGGGRKHLWYMPEEYIRQGRLSVKTDVYS 372 Query: 496 VGVIIIEILTGKK 458 G++I+E+LTG K Sbjct: 373 FGIVIMEVLTGCK 385
>LRRK2_HUMAN (Q5S007) Leucine-rich repeat serine/threonine-protein kinase 2 (EC| 2.7.11.1) (Dardarin) Length = 2527 Score = 46.2 bits (108), Expect(2) = 2e-05 Identities = 37/136 (27%), Positives = 60/136 (44%), Gaps = 13/136 (9%) Frame = -3 Query: 646 LVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEITY--QLDIYSVGVIIIEI 473 ++ KIAD+G+++ M + GT G+ APE G + Y Q D+YS G+++ +I Sbjct: 2011 IIAKIADYGIAQYCCRMGIKTS----EGTPGFRAPEVARGNVIYNQQADVYSFGLLLYDI 2066 Query: 472 LTGKKGYLAVDNVVESWSNKLEKSQSDVQLKQVRICAEIGI-----------ECTDFNPA 326 LT +VE E + ++Q K E G +C NP Sbjct: 2067 LT------TGGRIVEGLKFPNEFDELEIQGKLPDPVKEYGCAPWPMVEKLIKQCLKENPQ 2120 Query: 325 KRPGTKNIIDRLVSLD 278 +RP + + D L S + Sbjct: 2121 ERPTSAQVFDILNSAE 2136 Score = 21.9 bits (45), Expect(2) = 2e-05 Identities = 8/18 (44%), Positives = 12/18 (66%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 LH I++ DLKP N+ + Sbjct: 1985 LHSAMIIYRDLKPHNVLL 2002
>RAF1_RAT (P11345) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Raf-1) (C-RAF) (cRaf) Length = 648 Score = 41.2 bits (95), Expect(2) = 2e-05 Identities = 22/78 (28%), Positives = 39/78 (50%), Gaps = 4/78 (5%) Frame = -3 Query: 658 LDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFC----NGEITYQLDIYSVG 491 L L KI DFG++ G++ ++APE N ++Q D+YS G Sbjct: 476 LHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSFQSDVYSYG 535 Query: 490 VIIIEILTGKKGYLAVDN 437 +++ E++TG+ Y ++N Sbjct: 536 IVLYELMTGELPYSHINN 553 Score = 26.9 bits (58), Expect(2) = 2e-05 Identities = 10/18 (55%), Positives = 14/18 (77%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 LH +NI+H D+K NIF+ Sbjct: 459 LHAKNIIHRDMKSNNIFL 476
>RAF1_HUMAN (P04049) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Raf-1) (C-RAF) (cRaf) Length = 648 Score = 41.2 bits (95), Expect(2) = 2e-05 Identities = 22/78 (28%), Positives = 39/78 (50%), Gaps = 4/78 (5%) Frame = -3 Query: 658 LDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFC----NGEITYQLDIYSVG 491 L L KI DFG++ G++ ++APE N ++Q D+YS G Sbjct: 476 LHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSFQSDVYSYG 535 Query: 490 VIIIEILTGKKGYLAVDN 437 +++ E++TG+ Y ++N Sbjct: 536 IVLYELMTGELPYSHINN 553 Score = 26.9 bits (58), Expect(2) = 2e-05 Identities = 10/18 (55%), Positives = 14/18 (77%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 LH +NI+H D+K NIF+ Sbjct: 459 LHAKNIIHRDMKSNNIFL 476
>PKD1_DICDI (P34100) Developmentally-regulated protein kinase 1 (EC 2.7.11.1)| (Fragment) Length = 416 Score = 41.6 bits (96), Expect(2) = 2e-05 Identities = 42/182 (23%), Positives = 89/182 (48%), Gaps = 3/182 (1%) Frame = -3 Query: 637 KIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEITY--QLDIYSVGVIIIEILTG 464 K+ DFG S+ + T ++ GT Y+APE N + +D +++GV++ E++TG Sbjct: 174 KLTDFGFSK---KTVGGKNTSSVCGTFDYMAPEILNSSNGHGKPVDWWALGVVVYELVTG 230 Query: 463 KKGYLAVDNVVESWSNKLEKSQSDVQLKQVRICAEIGIECTDFNPAKRPGTKNIIDRLVS 284 K L N ES N+ K+ + + + EI K+ I +L+S Sbjct: 231 K---LPFSNSKESLLNR--KADFQLIFQNSYLSDEI---------------KDFIFQLLS 270 Query: 283 LDETDSMGGYIETSAVTSQQAENALEELH-QARPKVPGEISSEVSFVKV*L*LLINSRNV 107 +D + +G + ++ ++ + + + + LH +++ ++ G +S+ SF+ + + ++ Sbjct: 271 VDPSKRLGTF-DSCSIRNHKWFSDINWLHLESKYQIDGPLSTLNSFINCDFNINLLKKSK 329 Query: 106 SY 101 SY Sbjct: 330 SY 331 Score = 26.6 bits (57), Expect(2) = 2e-05 Identities = 10/18 (55%), Positives = 13/18 (72%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 LH NI++ DLKP NI + Sbjct: 150 LHAENIIYRDLKPENILI 167
>STK6_XENLA (Q91820) Serine/threonine-protein kinase Eg2 (EC 2.7.11.1) (pEg2)| (p46Eg265) Length = 407 Score = 42.4 bits (98), Expect(2) = 2e-05 Identities = 30/68 (44%), Positives = 38/68 (55%), Gaps = 1/68 (1%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEITYQ-LDIYSVGVI 485 LL N KIADFG S H SR T + GTL YL PE G + + +D++S+GV+ Sbjct: 270 LLGSNGELKIADFGWS--VHAPSSRRTT--LCGTLDYLPPEMIEGRMHDETVDLWSLGVL 325 Query: 484 IIEILTGK 461 E L GK Sbjct: 326 CYEFLVGK 333 Score = 25.8 bits (55), Expect(2) = 2e-05 Identities = 7/18 (38%), Positives = 13/18 (72%) Frame = -2 Query: 707 HQRNILHLDLKPANIFVG 654 H + ++H D+KP N+ +G Sbjct: 255 HSKKVIHRDIKPENLLLG 272
>CCRK_HUMAN (Q8IZL9) Cell cycle-related kinase (EC 2.7.11.22)| (Cyclin-kinase-activating kinase p42) (CDK-activating kinase p42) (CAK-kinase p42) Length = 346 Score = 40.0 bits (92), Expect(2) = 2e-05 Identities = 26/60 (43%), Positives = 34/60 (56%), Gaps = 2/60 (3%) Frame = -3 Query: 637 KIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEITYQ--LDIYSVGVIIIEILTG 464 KIADFG++R F SR T + T Y APE G Y +D++SVG I+ E+L G Sbjct: 142 KIADFGLARVFSPDGSRLYTHQV-ATRWYRAPELLYGARQYDQGVDLWSVGCIMGELLNG 200 Score = 28.1 bits (61), Expect(2) = 2e-05 Identities = 10/17 (58%), Positives = 13/17 (76%) Frame = -2 Query: 707 HQRNILHLDLKPANIFV 657 H NI+H DLKPAN+ + Sbjct: 119 HANNIVHRDLKPANLLI 135
>RAF1_XENLA (P09560) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (C-RAF) Length = 638 Score = 40.8 bits (94), Expect(2) = 2e-05 Identities = 21/73 (28%), Positives = 37/73 (50%), Gaps = 4/73 (5%) Frame = -3 Query: 658 LDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFC----NGEITYQLDIYSVG 491 L L KI DFG++ + G++ ++APE N ++Q D+YS G Sbjct: 467 LHEGLTVKIGDFGLATVKTRWSGSQQVEQLTGSILWMAPEVIRMQDNNPFSFQSDVYSYG 526 Query: 490 VIIIEILTGKKGY 452 +++ E++TG+ Y Sbjct: 527 IVLYELMTGELPY 539 Score = 26.9 bits (58), Expect(2) = 2e-05 Identities = 10/18 (55%), Positives = 14/18 (77%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 LH +NI+H D+K NIF+ Sbjct: 450 LHAKNIIHRDMKSNNIFL 467
>IRAK1_HUMAN (P51617) Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1)| (IRAK-1) Length = 712 Score = 48.1 bits (113), Expect = 3e-05 Identities = 27/76 (35%), Positives = 40/76 (52%), Gaps = 8/76 (10%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFH-------EMQSRAITVNIRGTLGYLAPEFC-NGEITYQLD 506 LLD L PK+ DFG++R + A T +RGTL YL E+ G + D Sbjct: 347 LLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTD 406 Query: 505 IYSVGVIIIEILTGKK 458 +S GV+++E L G++ Sbjct: 407 TFSFGVVVLETLAGQR 422
>CRI4_MAIZE (O24585) Putative receptor protein kinase CRINKLY4 precursor (EC| 2.7.11.1) Length = 901 Score = 48.1 bits (113), Expect = 3e-05 Identities = 40/142 (28%), Positives = 66/142 (46%), Gaps = 18/142 (12%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGE-ITYQLDIYSVGVI 485 L+D + ++ADFG+S ++ GTLGYL PE+ +T + D+YS GV+ Sbjct: 641 LIDEDHNARVADFGLSILGPADSGTPLSELPAGTLGYLDPEYYRLHYLTTKSDVYSFGVV 700 Query: 484 IIEILTGKKGYLAVD------NVVESWSNKLEKS-----------QSDVQLKQVRICAEI 356 ++EIL+G+K A+D N+VE W+ L K+ L+ ++ A + Sbjct: 701 LLEILSGRK---AIDMQFEEGNIVE-WAVPLIKAGDIFAILDPVLSPPSDLEALKKIASV 756 Query: 355 GIECTDFNPAKRPGTKNIIDRL 290 +C RP + L Sbjct: 757 ACKCVRMRGKDRPSMDKVTTAL 778
>FGFR1_CHICK (P21804) Basic fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) Length = 819 Score = 48.1 bits (113), Expect = 3e-05 Identities = 44/150 (29%), Positives = 69/150 (46%), Gaps = 2/150 (1%) Frame = -3 Query: 670 RTYLLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEI-TYQLDIYSV 494 R L+ + V KIADFG++R H + T N R + ++APE I T+Q D++S Sbjct: 625 RNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSF 684 Query: 493 GVIIIEILT-GKKGYLAVDNVVESWSNKLEKSQSDVQLKQVRICAEIGIECTDFNPAKRP 317 GV++ EI T G Y V V E + E + D + +C P++RP Sbjct: 685 GVLLWEIFTLGGSPYPGVP-VEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRP 743 Query: 316 GTKNIIDRLVSLDETDSMGGYIETSAVTSQ 227 K +++ L + S Y++ S Q Sbjct: 744 TFKQLVEDLDRIVAMTSNQEYLDLSVPLDQ 773
>ATG1_BOTCI (Q6H9I1) Serine/threonine-protein kinase ATG1 (EC 2.7.11.1)| (Autophagy-related protein 1) (Botryotinia fuckeliana putative kinase exons 1-3) Length = 952 Score = 45.1 bits (105), Expect(2) = 3e-05 Identities = 25/85 (29%), Positives = 51/85 (60%), Gaps = 1/85 (1%) Frame = -3 Query: 637 KIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGE-ITYQLDIYSVGVIIIEILTGK 461 K+ADFG +R + S ++ + G+ Y+APE E + D++S+G ++ E++TG+ Sbjct: 212 KLADFGFAR---SLPSTSLAETLCGSPLYMAPEILRYEKYDARADLWSIGTVLYEMMTGR 268 Query: 460 KGYLAVDNVVESWSNKLEKSQSDVQ 386 + A+++V K+EK+Q +++ Sbjct: 269 PPFKAINHV--QLLQKIEKNQDEIR 291 Score = 22.3 bits (46), Expect(2) = 3e-05 Identities = 7/18 (38%), Positives = 13/18 (72%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 L +R+ +H D+KP N+ + Sbjct: 157 LRERDFVHRDVKPQNLLL 174
>PKNA2_BIFLO (Q8G4G1) Probable serine/threonine-protein kinase pknA2 (EC| 2.7.11.1) Length = 757 Score = 43.5 bits (101), Expect(2) = 3e-05 Identities = 25/60 (41%), Positives = 38/60 (63%), Gaps = 1/60 (1%) Frame = -3 Query: 637 KIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFC-NGEITYQLDIYSVGVIIIEILTGK 461 +I DFG+++ + + + T + GT YLAPE N + T Q D+YSVG++ E+LTGK Sbjct: 155 QITDFGLAKAASQA-TLSSTGMLLGTAAYLAPEMIENNQATAQGDLYSVGIMAWEMLTGK 213 Score = 23.9 bits (50), Expect(2) = 3e-05 Identities = 7/17 (41%), Positives = 12/17 (70%) Frame = -2 Query: 707 HQRNILHLDLKPANIFV 657 H+ ++H D+KP NI + Sbjct: 132 HRAGVVHRDIKPENILI 148
>PKWA_THECU (P49695) Probable serine/threonine-protein kinase pkwA (EC| 2.7.11.1) Length = 742 Score = 45.8 bits (107), Expect(2) = 3e-05 Identities = 42/163 (25%), Positives = 77/163 (47%), Gaps = 18/163 (11%) Frame = -3 Query: 640 PKIADFGVSRCFHEMQSRAITVN--IRGTLGYLAPEFCNG-EITYQLDIYSVGVIIIEIL 470 P++ DFGV+R + S +T + + GTL Y++PE +G ++ D++S+G ++ Sbjct: 151 PRVIDFGVAR---PLDSSVMTQSGAVIGTLAYMSPEQTDGSQVGPASDVFSLGTVLAFAA 207 Query: 469 TGKKGYLA--VDNVVESWSN---KLEKSQSDVQLKQVRICAEIGIECTDFNPAKRPGTKN 305 TG+ ++A + ++ S +L + D++ E+ C + NP RP T Sbjct: 208 TGRSPFMADSIGEIIARISGPPPELPELPDDLR--------ELVYACWEQNPDLRPTTAE 259 Query: 304 IIDRLVSLDET----------DSMGGYIETSAVTSQQAENALE 206 ++ +L S D T D +G + A TS A+E Sbjct: 260 LLAQL-STDHTGDDWPPPHLSDLIGSMLPLGATTSPNPSLAIE 301 Score = 21.6 bits (44), Expect(2) = 3e-05 Identities = 7/16 (43%), Positives = 11/16 (68%) Frame = -2 Query: 710 LHQRNILHLDLKPANI 663 +H ++H D KP+NI Sbjct: 129 IHACGLVHRDFKPSNI 144
>PKN2_BACSU (O34507) Probable serine/threonine-protein kinase yloP (EC| 2.7.11.1) Length = 648 Score = 41.6 bits (96), Expect(2) = 3e-05 Identities = 24/67 (35%), Positives = 43/67 (64%), Gaps = 3/67 (4%) Frame = -3 Query: 652 GNLVPKIADFGVSRCFHEMQSRAITV--NIRGTLGYLAPEFCNGEI-TYQLDIYSVGVII 482 GN+ K+ DFG++ + S IT ++ G++ YL+PE G + T + DIY++G+++ Sbjct: 146 GNI--KVTDFGIATA---LSSTTITHTNSVLGSVHYLSPEQARGGLATKKSDIYALGIVL 200 Query: 481 IEILTGK 461 E+LTG+ Sbjct: 201 FELLTGR 207 Score = 25.8 bits (55), Expect(2) = 3e-05 Identities = 9/17 (52%), Positives = 12/17 (70%) Frame = -2 Query: 707 HQRNILHLDLKPANIFV 657 HQ I+H D+KP NI + Sbjct: 126 HQNQIVHRDIKPHNILI 142
>ST17A_HUMAN (Q9UEE5) Serine/threonine-protein kinase 17A (EC 2.7.11.1) (DAP| kinase-related apoptosis-inducing protein kinase 1) Length = 414 Score = 37.7 bits (86), Expect(2) = 3e-05 Identities = 24/67 (35%), Positives = 36/67 (53%), Gaps = 1/67 (1%) Frame = -3 Query: 637 KIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGE-ITYQLDIYSVGVIIIEILTGK 461 KI DFG+SR + I GT Y+APE + + I+ D++S+GV+ +LTG Sbjct: 204 KIVDFGLSRILKNSEELR---EIMGTPEYVAPEILSYDPISMATDMWSIGVLTYVMLTGI 260 Query: 460 KGYLAVD 440 +L D Sbjct: 261 SPFLGND 267 Score = 29.6 bits (65), Expect(2) = 3e-05 Identities = 11/18 (61%), Positives = 15/18 (83%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 LH R+++HLDLKP NI + Sbjct: 177 LHTRDVVHLDLKPQNILL 194
>DAPK2_MOUSE (Q8VDF3) Death-associated protein kinase 2 (EC 2.7.11.1) (DAP| kinase 2) (DAP-kinase-related protein 1) (DRP-1) Length = 370 Score = 41.2 bits (95), Expect(2) = 3e-05 Identities = 31/86 (36%), Positives = 50/86 (58%), Gaps = 4/86 (4%) Frame = -3 Query: 661 LLDGNL-VP--KIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGE-ITYQLDIYSV 494 LLD N+ +P K+ DFG++ HE++ NI GT ++APE N E + + D++S+ Sbjct: 157 LLDKNIPIPHIKLIDFGLA---HEIEDGVEFKNIFGTPEFVAPEIVNYEPLGLEADMWSI 213 Query: 493 GVIIIEILTGKKGYLAVDNVVESWSN 416 GVI +L+G +L D E+ +N Sbjct: 214 GVITYILLSGASPFLG-DTKQETLAN 238 Score = 26.2 bits (56), Expect(2) = 3e-05 Identities = 10/18 (55%), Positives = 12/18 (66%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 LH + I H DLKP NI + Sbjct: 140 LHTKKIAHFDLKPENIML 157
>DAPK2_HUMAN (Q9UIK4) Death-associated protein kinase 2 (EC 2.7.11.1) (DAP| kinase 2) (DAP-kinase-related protein 1) (DRP-1) Length = 370 Score = 41.2 bits (95), Expect(2) = 3e-05 Identities = 31/86 (36%), Positives = 50/86 (58%), Gaps = 4/86 (4%) Frame = -3 Query: 661 LLDGNL-VP--KIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGE-ITYQLDIYSV 494 LLD N+ +P K+ DFG++ HE++ NI GT ++APE N E + + D++S+ Sbjct: 157 LLDKNIPIPHIKLIDFGLA---HEIEDGVEFKNIFGTPEFVAPEIVNYEPLGLEADMWSI 213 Query: 493 GVIIIEILTGKKGYLAVDNVVESWSN 416 GVI +L+G +L D E+ +N Sbjct: 214 GVITYILLSGASPFLG-DTKQETLAN 238 Score = 26.2 bits (56), Expect(2) = 3e-05 Identities = 10/18 (55%), Positives = 12/18 (66%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 LH + I H DLKP NI + Sbjct: 140 LHTKKIAHFDLKPENIML 157
>CDC2_RANDY (Q9W739) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) Length = 302 Score = 40.8 bits (94), Expect(2) = 3e-05 Identities = 27/69 (39%), Positives = 39/69 (56%), Gaps = 2/69 (2%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEITYQ--LDIYSVGV 488 L+D V K+ADFG++R F + R T + TL Y APE G + Y +D++S+G Sbjct: 135 LIDSKGVIKLADFGLARAF-GIPVRVYTHEV-VTLWYRAPEVLLGSVRYSTPVDVWSIGT 192 Query: 487 IIIEILTGK 461 I EI + K Sbjct: 193 IFAEIASKK 201 Score = 26.6 bits (57), Expect(2) = 3e-05 Identities = 9/17 (52%), Positives = 12/17 (70%) Frame = -2 Query: 707 HQRNILHLDLKPANIFV 657 H R +LH DLKP N+ + Sbjct: 120 HARRVLHRDLKPQNLLI 136
>FGFR1_MOUSE (P16092) Basic fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) (FGFR-1) (bFGF-R) (MFR) Length = 822 Score = 47.8 bits (112), Expect = 3e-05 Identities = 44/150 (29%), Positives = 69/150 (46%), Gaps = 2/150 (1%) Frame = -3 Query: 670 RTYLLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEI-TYQLDIYSV 494 R L+ + V KIADFG++R H + T N R + ++APE I T+Q D++S Sbjct: 627 RNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSF 686 Query: 493 GVIIIEILT-GKKGYLAVDNVVESWSNKLEKSQSDVQLKQVRICAEIGIECTDFNPAKRP 317 GV++ EI T G Y V V E + E + D + +C P++RP Sbjct: 687 GVLLWEIFTLGGSPYPGVP-VEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRP 745 Query: 316 GTKNIIDRLVSLDETDSMGGYIETSAVTSQ 227 K +++ L + S Y++ S Q Sbjct: 746 TFKQLVEDLDRIVALTSNQEYLDLSIPLDQ 775
>FGFR1_HUMAN (P11362) Basic fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) (FGFR-1) (bFGF-R) (Fms-like tyrosine kinase 2) (c-fgr) (CD331 antigen) Length = 822 Score = 47.8 bits (112), Expect = 3e-05 Identities = 44/150 (29%), Positives = 69/150 (46%), Gaps = 2/150 (1%) Frame = -3 Query: 670 RTYLLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEI-TYQLDIYSV 494 R L+ + V KIADFG++R H + T N R + ++APE I T+Q D++S Sbjct: 627 RNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSF 686 Query: 493 GVIIIEILT-GKKGYLAVDNVVESWSNKLEKSQSDVQLKQVRICAEIGIECTDFNPAKRP 317 GV++ EI T G Y V V E + E + D + +C P++RP Sbjct: 687 GVLLWEIFTLGGSPYPGVP-VEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRP 745 Query: 316 GTKNIIDRLVSLDETDSMGGYIETSAVTSQ 227 K +++ L + S Y++ S Q Sbjct: 746 TFKQLVEDLDRIVALTSNQEYLDLSMPLDQ 775
>ULK1_MOUSE (O70405) Serine/threonine-protein kinase ULK1 (EC 2.7.11.1)| (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1) Length = 1051 Score = 40.0 bits (92), Expect(2) = 4e-05 Identities = 24/69 (34%), Positives = 39/69 (56%), Gaps = 1/69 (1%) Frame = -3 Query: 649 NLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGE-ITYQLDIYSVGVIIIEI 473 N+ KIADFG +R +QS + + G+ Y+APE + + D++S+G I+ + Sbjct: 158 NIRVKIADFGFARY---LQSNMMAATLCGSPMYMAPEVIMSQHYDGKADLWSIGTIVYQC 214 Query: 472 LTGKKGYLA 446 LTGK + A Sbjct: 215 LTGKAPFQA 223 Score = 26.9 bits (58), Expect(2) = 4e-05 Identities = 10/18 (55%), Positives = 13/18 (72%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 LH + I+H DLKP NI + Sbjct: 129 LHSKGIIHRDLKPQNILL 146
>RIPK4_HUMAN (P57078) Receptor-interacting serine/threonine-protein kinase 4 (EC| 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase) Length = 832 Score = 41.2 bits (95), Expect(2) = 4e-05 Identities = 25/81 (30%), Positives = 45/81 (55%), Gaps = 4/81 (4%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVN-IRGTLGYLAPEFCNGE---ITYQLDIYSV 494 LLD + KI+DFG+++C S ++++ + GT+ YL PE + + D+YS Sbjct: 150 LLDAHYHVKISDFGLAKCNGLSHSHDLSMDGLFGTIAYLPPERIREKSRLFDTKHDVYSF 209 Query: 493 GVIIIEILTGKKGYLAVDNVV 431 ++I +LT KK + N++ Sbjct: 210 AIVIWGVLTQKKPFADEKNIL 230 Score = 25.8 bits (55), Expect(2) = 4e-05 Identities = 10/13 (76%), Positives = 12/13 (92%) Frame = -2 Query: 695 ILHLDLKPANIFV 657 +LHLDLKPANI + Sbjct: 139 LLHLDLKPANILL 151
>PKN2_CLOAB (Q97IC2) Probable serine/threonine protein kinase CAC1728 (EC| 2.7.11.1) Length = 657 Score = 42.4 bits (98), Expect(2) = 4e-05 Identities = 24/64 (37%), Positives = 38/64 (59%), Gaps = 2/64 (3%) Frame = -3 Query: 637 KIADFGVSRCFHEMQSRAITVN-IRGTLGYLAPEFCNG-EITYQLDIYSVGVIIIEILTG 464 K+ DFG+++ +E S T N + G+ YL+PE G + + DIYS G+++ E+ TG Sbjct: 148 KVTDFGIAKASNE--STITTTNKVVGSAHYLSPEQAQGIPVDCRTDIYSFGIVLYEMATG 205 Query: 463 KKGY 452 K Y Sbjct: 206 KVPY 209 Score = 24.6 bits (52), Expect(2) = 4e-05 Identities = 9/17 (52%), Positives = 12/17 (70%) Frame = -2 Query: 707 HQRNILHLDLKPANIFV 657 H+ I+H D+KP NI V Sbjct: 125 HKNGIVHRDIKPHNIMV 141
>HCK_MOUSE (P08103) Tyrosine-protein kinase HCK (EC 2.7.10.2)| (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK) Length = 523 Score = 41.6 bits (96), Expect(2) = 4e-05 Identities = 34/119 (28%), Positives = 61/119 (51%), Gaps = 4/119 (3%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCN-GEITYQLDIYSVGVI 485 L+ +LV KIADFG++R + + A + + + APE N G T + D++S G++ Sbjct: 385 LVSASLVCKIADFGLARIIEDNEYTA-REGAKFPIKWTAPEAINFGSFTIKSDVWSFGIL 443 Query: 484 IIEILT-GKKGYLAVDN--VVESWSNKLEKSQSDVQLKQVRICAEIGIECTDFNPAKRP 317 ++EI+T G+ Y + N V+ + + + D +++ I I C P +RP Sbjct: 444 LMEIVTYGRIPYPGMSNPEVIRALEHGYRMPRPDNCPEEL---YNIMIRCWKNRPEERP 499 Score = 25.4 bits (54), Expect(2) = 4e-05 Identities = 10/18 (55%), Positives = 13/18 (72%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 + QRN +H DL+ ANI V Sbjct: 369 IEQRNYIHRDLRAANILV 386
>DUN1_YEAST (P39009) DNA damage response protein kinase DUN1 (EC 2.7.11.1)| Length = 513 Score = 38.1 bits (87), Expect(2) = 4e-05 Identities = 24/59 (40%), Positives = 35/59 (59%), Gaps = 1/59 (1%) Frame = -3 Query: 637 KIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGE-ITYQLDIYSVGVIIIEILTG 464 KIADFG+++ EMQ T + GT Y+APE + T ++D++S GVI+ L G Sbjct: 362 KIADFGLAKFTGEMQ---FTNTLCGTPSYVAPEVLTKKGYTSKVDLWSAGVILYVCLCG 417 Score = 28.9 bits (63), Expect(2) = 4e-05 Identities = 10/18 (55%), Positives = 15/18 (83%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 LH++NI+H D+KP NI + Sbjct: 319 LHEQNIIHRDIKPENILL 336
>HCK_RAT (P50545) Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK)| (Hemopoietic cell kinase) Length = 502 Score = 41.6 bits (96), Expect(2) = 4e-05 Identities = 34/119 (28%), Positives = 61/119 (51%), Gaps = 4/119 (3%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCN-GEITYQLDIYSVGVI 485 L+ +LV KIADFG++R + + A + + + APE N G T + D++S G++ Sbjct: 364 LVSASLVCKIADFGLARIIEDNEYTA-REGAKFPIKWTAPEAINFGSFTIKSDVWSFGIL 422 Query: 484 IIEILT-GKKGYLAVDN--VVESWSNKLEKSQSDVQLKQVRICAEIGIECTDFNPAKRP 317 ++EI+T G+ Y + N V+ + + + D +++ I I C P +RP Sbjct: 423 LMEIVTYGRIPYPGMSNPEVIRALEHGYRMPRPDNCPEEL---YSIMIRCWKNRPEERP 478 Score = 25.4 bits (54), Expect(2) = 4e-05 Identities = 10/18 (55%), Positives = 13/18 (72%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 + QRN +H DL+ ANI V Sbjct: 348 IEQRNYIHRDLRAANILV 365
>CCRK_PONPY (Q5R7I7) Cell cycle-related kinase (EC 2.7.11.22)| Length = 346 Score = 38.9 bits (89), Expect(2) = 4e-05 Identities = 25/60 (41%), Positives = 34/60 (56%), Gaps = 2/60 (3%) Frame = -3 Query: 637 KIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEITYQ--LDIYSVGVIIIEILTG 464 KIADFG++R F SR T + T Y APE G Y +D+++VG I+ E+L G Sbjct: 142 KIADFGLARVFSPDGSRLYTHQV-ATRWYRAPELLYGARQYDQGVDLWAVGCIMGELLNG 200 Score = 28.1 bits (61), Expect(2) = 4e-05 Identities = 10/17 (58%), Positives = 13/17 (76%) Frame = -2 Query: 707 HQRNILHLDLKPANIFV 657 H NI+H DLKPAN+ + Sbjct: 119 HANNIVHRDLKPANLLI 135
>SPKA_SYNY3 (Q9FAB3) Serine/threonine-protein kinase A (EC 2.7.11.1)| Length = 521 Score = 47.4 bits (111), Expect = 4e-05 Identities = 37/132 (28%), Positives = 63/132 (47%), Gaps = 4/132 (3%) Frame = -3 Query: 652 GNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNG-EITYQLDIYSVGVIIIE 476 G LV KI DFG+++ + T GTL Y +PE G E+ + DIYS+GV++ E Sbjct: 163 GELV-KILDFGIAKLVQAAEESK-TQAFMGTLAYCSPEQMEGKELDSRSDIYSLGVMMYE 220 Query: 475 ILTGKKGYLAVDNVVESWSNKLEKSQSDVQLKQVRICAEIG---IECTDFNPAKRPGTKN 305 +LTG+ ++ W ++ + +I A + + C +P RP + + Sbjct: 221 MLTGEMPLFPDNSSFGGWYEAHHHTKPHPFSARYKIPASLEALVMNCLAKSPKGRPQSVD 280 Query: 304 IIDRLVSLDETD 269 +I R + E + Sbjct: 281 VIIRAIDAIEAE 292
>KOK0_YEAST (Q12236) Probable serine/threonine-protein kinase YOL100W (EC| 2.7.11.1) Length = 1081 Score = 41.2 bits (95), Expect(2) = 5e-05 Identities = 24/84 (28%), Positives = 42/84 (50%), Gaps = 10/84 (11%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFH---------EMQSRAITVNIRGTLGYLAPEFCNGEIT-YQ 512 LLDG + K+ DFG ++ + E + + GT Y++PE N T Y+ Sbjct: 310 LLDGEMKIKLTDFGTAKLLNPTNNSVSKPEYDLSTRSKSFVGTAEYVSPELLNDSFTDYR 369 Query: 511 LDIYSVGVIIIEILTGKKGYLAVD 440 DI++ G I+ +++ GK + A + Sbjct: 370 CDIWAFGCILFQMIAGKPPFKATN 393 Score = 25.4 bits (54), Expect(2) = 5e-05 Identities = 9/18 (50%), Positives = 12/18 (66%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 LH I+H D+KP NI + Sbjct: 294 LHSNGIIHRDIKPENILL 311
>M3K1_ARATH (O22040) Mitogen-activated protein kinase kinase kinase 1 (EC| 2.7.11.25) (Arabidospsis NPK1-related protein kinase 1) Length = 666 Score = 42.4 bits (98), Expect(2) = 5e-05 Identities = 24/68 (35%), Positives = 40/68 (58%), Gaps = 1/68 (1%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPE-FCNGEITYQLDIYSVGVI 485 L+D K+ADFG S+ E+ + +++GT ++APE ++ DI+SVG Sbjct: 204 LVDNKGCIKLADFGASKQVAELATMTGAKSMKGTPYWMAPEVILQTGHSFSADIWSVGCT 263 Query: 484 IIEILTGK 461 +IE++TGK Sbjct: 264 VIEMVTGK 271 Score = 24.3 bits (51), Expect(2) = 5e-05 Identities = 10/18 (55%), Positives = 12/18 (66%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 LH I+H D+K ANI V Sbjct: 188 LHNHAIMHRDIKGANILV 205
>RAF1_CHICK (P05625) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (RAF-1) (C-RAF) (MIL proto-oncogene serine/threonine-protein kinase) (C-MIL) Length = 647 Score = 39.7 bits (91), Expect(2) = 5e-05 Identities = 21/78 (26%), Positives = 39/78 (50%), Gaps = 4/78 (5%) Frame = -3 Query: 658 LDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFC----NGEITYQLDIYSVG 491 L L KI DFG++ G++ ++APE + ++Q D+YS G Sbjct: 476 LHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSILWMAPEVIRMQDSNPFSFQSDVYSYG 535 Query: 490 VIIIEILTGKKGYLAVDN 437 +++ E++TG+ Y ++N Sbjct: 536 IVLYELMTGELPYSHINN 553 Score = 26.9 bits (58), Expect(2) = 5e-05 Identities = 10/18 (55%), Positives = 14/18 (77%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 LH +NI+H D+K NIF+ Sbjct: 459 LHAKNIIHRDMKSNNIFL 476
>HCK_HUMAN (P08631) Tyrosine-protein kinase HCK (EC 2.7.10.2)| (p59-HCK/p60-HCK) (Hemopoietic cell kinase) Length = 525 Score = 41.2 bits (95), Expect(2) = 5e-05 Identities = 26/77 (33%), Positives = 45/77 (58%), Gaps = 2/77 (2%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCN-GEITYQLDIYSVGVI 485 L+ +LV KIADFG++R + + A + + + APE N G T + D++S G++ Sbjct: 387 LVSASLVCKIADFGLARVIEDNEYTA-REGAKFPIKWTAPEAINFGSFTIKSDVWSFGIL 445 Query: 484 IIEILT-GKKGYLAVDN 437 ++EI+T G+ Y + N Sbjct: 446 LMEIVTYGRIPYPGMSN 462 Score = 25.4 bits (54), Expect(2) = 5e-05 Identities = 10/18 (55%), Positives = 13/18 (72%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 + QRN +H DL+ ANI V Sbjct: 371 IEQRNYIHRDLRAANILV 388
>RIPK3_HUMAN (Q9Y572) Receptor-interacting serine/threonine-protein kinase 3 (EC| 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) Length = 518 Score = 42.7 bits (99), Expect(2) = 5e-05 Identities = 27/71 (38%), Positives = 39/71 (54%), Gaps = 3/71 (4%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEF---CNGEITYQLDIYSVG 491 L D L K+ADFG+S QS + GTLGYLAPE N + + D+YS G Sbjct: 149 LPDPELHVKLADFGLSTFQGGSQSGTGSGEPGGTLGYLAPELFVNVNRKASTASDVYSFG 208 Query: 490 VIIIEILTGKK 458 +++ +L G++ Sbjct: 209 ILMWAVLAGRE 219 Score = 23.9 bits (50), Expect(2) = 5e-05 Identities = 10/18 (55%), Positives = 14/18 (77%), Gaps = 2/18 (11%) Frame = -2 Query: 710 LHQRN--ILHLDLKPANI 663 LH +N +LH DLKP+N+ Sbjct: 131 LHDQNPVLLHRDLKPSNV 148
>SRK4_SPOLA (P42690) Tyrosine-protein kinase isoform SRK4 (EC 2.7.10.2)| Length = 506 Score = 42.7 bits (99), Expect(2) = 5e-05 Identities = 37/145 (25%), Positives = 68/145 (46%), Gaps = 6/145 (4%) Frame = -3 Query: 670 RTYLLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFC-NGEITYQLDIYSV 494 R L+ + + K+ADFG++R E A + + + + APE T + D++S Sbjct: 363 RNILVGEHKICKVADFGLARVIDEEIYEA-KLGAKFPIKWTAPEAAMYSRFTIKSDVWSF 421 Query: 493 GVIIIEILT-GKKGYLAVDNVVESWSNKLEKSQSDVQLKQVRICAE----IGIECTDFNP 329 G+++ E++T G+ Y + N + LE+ Q ++ + C E I ++C +P Sbjct: 422 GIVLYEVITYGRFPYPGMTN-----AQVLEQIQQSYRMPRPMGCPEKLYAIMMDCWREDP 476 Query: 328 AKRPGTKNIIDRLVSLDETDSMGGY 254 A RP + + +L T GY Sbjct: 477 ASRPTFETLSWQLEEFFTTGDDAGY 501 Score = 23.9 bits (50), Expect(2) = 5e-05 Identities = 10/19 (52%), Positives = 12/19 (63%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFVG 654 L Q+N +H DL NI VG Sbjct: 350 LEQQNYIHRDLAARNILVG 368
>ST17A_RABIT (Q9GM70) Serine/threonine-protein kinase 17A (EC 2.7.11.1) (DAP| kinase-related apoptosis-inducing protein kinase 1) (rDRAK1) Length = 397 Score = 38.9 bits (89), Expect(2) = 5e-05 Identities = 27/75 (36%), Positives = 41/75 (54%), Gaps = 1/75 (1%) Frame = -3 Query: 637 KIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGE-ITYQLDIYSVGVIIIEILTGK 461 KI DFG+SR + I GT Y+APE + + I+ D++S+GV+ +LTG Sbjct: 187 KIVDFGLSRIVKNSEELR---EIMGTPEYVAPEILSYDPISMATDMWSIGVLTYVMLTGI 243 Query: 460 KGYLAVDNVVESWSN 416 +L DN E++ N Sbjct: 244 SPFLG-DNKQETFLN 257 Score = 27.7 bits (60), Expect(2) = 5e-05 Identities = 10/18 (55%), Positives = 14/18 (77%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 LH +++HLDLKP NI + Sbjct: 160 LHTHDVVHLDLKPQNILL 177
>CDC2_ORYCU (Q9DGA5) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 39.3 bits (90), Expect(2) = 5e-05 Identities = 28/69 (40%), Positives = 37/69 (53%), Gaps = 2/69 (2%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEITYQ--LDIYSVGV 488 L+D V K+ADFG+SR F + R T + TL Y APE G Y +D++S G Sbjct: 135 LIDNKGVIKLADFGLSRAF-GVPVRVYTHEV-VTLWYRAPEVLLGSPRYSTPVDVWSTGT 192 Query: 487 IIIEILTGK 461 I E+ T K Sbjct: 193 IFAELATKK 201 Score = 27.3 bits (59), Expect(2) = 5e-05 Identities = 9/17 (52%), Positives = 13/17 (76%) Frame = -2 Query: 707 HQRNILHLDLKPANIFV 657 H+R +LH DLKP N+ + Sbjct: 120 HRRRVLHRDLKPQNLLI 136
>PKN1_COREF (Q8FUI5) Probable serine/threonine protein kinase CE0033 (EC| 2.7.11.1) Length = 660 Score = 39.7 bits (91), Expect(2) = 6e-05 Identities = 20/61 (32%), Positives = 35/61 (57%), Gaps = 2/61 (3%) Frame = -3 Query: 637 KIADFGVSRCFHEMQSRAI-TVNIRGTLGYLAPEFCNGE-ITYQLDIYSVGVIIIEILTG 464 K+ DFG++R + S T + GT YL+PE G+ + D+Y+ G ++ E++TG Sbjct: 151 KVMDFGIARALDDSTSAMTQTAAVIGTAQYLSPEQARGKPADARSDVYAAGCVLYELVTG 210 Query: 463 K 461 + Sbjct: 211 R 211 Score = 26.6 bits (57), Expect(2) = 6e-05 Identities = 9/17 (52%), Positives = 13/17 (76%) Frame = -2 Query: 707 HQRNILHLDLKPANIFV 657 H+ I+H D+KPANI + Sbjct: 128 HEAGIIHRDVKPANIMI 144
>M3K2_ARATH (Q9FZ36) Mitogen-activated protein kinase kinase kinase 2 (EC| 2.7.11.25) (Arabidospsis NPK1-related protein kinase 2) Length = 651 Score = 42.0 bits (97), Expect(2) = 6e-05 Identities = 24/68 (35%), Positives = 41/68 (60%), Gaps = 1/68 (1%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPE-FCNGEITYQLDIYSVGVI 485 L+D K+ADFG S+ E+ + + +++GT ++APE ++ DI+SVG Sbjct: 203 LVDNQGCIKLADFGASKQVAELATISGAKSMKGTPYWMAPEVILQTGHSFSADIWSVGCT 262 Query: 484 IIEILTGK 461 +IE++TGK Sbjct: 263 VIEMVTGK 270 Score = 24.3 bits (51), Expect(2) = 6e-05 Identities = 10/18 (55%), Positives = 12/18 (66%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 LH I+H D+K ANI V Sbjct: 187 LHNHAIMHRDIKGANILV 204
>PKN1_CORGL (Q8NU98) Probable serine/threonine protein kinase pknB (EC| 2.7.11.1) Length = 646 Score = 40.4 bits (93), Expect(2) = 6e-05 Identities = 22/61 (36%), Positives = 36/61 (59%), Gaps = 2/61 (3%) Frame = -3 Query: 637 KIADFGVSRCFHEMQSRAI-TVNIRGTLGYLAPEFCNGE-ITYQLDIYSVGVIIIEILTG 464 K+ DFG++R ++ S T + GT YL+PE G+ + DIY+ G ++ E++TG Sbjct: 151 KVMDFGIARAVNDSTSAMTQTSAVIGTAQYLSPEQARGKPADARSDIYATGCVMYELVTG 210 Query: 463 K 461 K Sbjct: 211 K 211 Score = 25.8 bits (55), Expect(2) = 6e-05 Identities = 9/17 (52%), Positives = 12/17 (70%) Frame = -2 Query: 707 HQRNILHLDLKPANIFV 657 H I+H D+KPANI + Sbjct: 128 HDAGIIHRDVKPANIMI 144
>NLK_MOUSE (O54949) Serine/threonine kinase NLK (EC 2.7.11.24) (Nemo-like| kinase) Length = 515 Score = 39.7 bits (91), Expect(2) = 6e-05 Identities = 27/66 (40%), Positives = 37/66 (56%), Gaps = 2/66 (3%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEITYQ--LDIYSVGV 488 L++ N V KI DFG++R +SR +T + T Y APE G Y +DI+SVG Sbjct: 259 LVNSNCVLKICDFGLARVEELDESRHMTQEVV-TQYYRAPEILMGSRHYSNAIDIWSVGC 317 Query: 487 IIIEIL 470 I E+L Sbjct: 318 IFAELL 323 Score = 26.6 bits (57), Expect(2) = 6e-05 Identities = 10/18 (55%), Positives = 12/18 (66%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 LH ILH D+KP N+ V Sbjct: 243 LHSAGILHRDIKPGNLLV 260
>NLK_HUMAN (Q9UBE8) Serine/threonine kinase NLK (EC 2.7.11.24) (Nemo-like| kinase) (LAK1 protein) Length = 515 Score = 39.7 bits (91), Expect(2) = 6e-05 Identities = 27/66 (40%), Positives = 37/66 (56%), Gaps = 2/66 (3%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEITYQ--LDIYSVGV 488 L++ N V KI DFG++R +SR +T + T Y APE G Y +DI+SVG Sbjct: 259 LVNSNCVLKICDFGLARVEELDESRHMTQEVV-TQYYRAPEILMGSRHYSNAIDIWSVGC 317 Query: 487 IIIEIL 470 I E+L Sbjct: 318 IFAELL 323 Score = 26.6 bits (57), Expect(2) = 6e-05 Identities = 10/18 (55%), Positives = 12/18 (66%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 LH ILH D+KP N+ V Sbjct: 243 LHSAGILHRDIKPGNLLV 260
>KPK19_ARATH (Q39030) Serine/threonine-protein kinase AtPK19 (EC 2.7.11.1)| (Ribosomal-protein S6 kinase homolog) Length = 471 Score = 38.5 bits (88), Expect(2) = 6e-05 Identities = 24/71 (33%), Positives = 43/71 (60%), Gaps = 1/71 (1%) Frame = -3 Query: 658 LDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGE-ITYQLDIYSVGVII 482 +DG+++ + DFG+++ F E + ++ GT Y+APE G+ D +SVG+++ Sbjct: 273 VDGHVM--LTDFGLAKEFEE---NTRSNSMCGTTEYMAPEIVRGKGHDKAADWWSVGILL 327 Query: 481 IEILTGKKGYL 449 E+LTGK +L Sbjct: 328 YEMLTGKPPFL 338 Score = 27.7 bits (60), Expect(2) = 6e-05 Identities = 10/18 (55%), Positives = 14/18 (77%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 LH++ I+H DLKP NI + Sbjct: 254 LHEKGIMHRDLKPENILM 271
>STK6_MOUSE (P97477) Serine/threonine-protein kinase 6 (EC 2.7.11.1)| (Aurora-family kinase 1) (Aurora/IPL1-related kinase 1) (Ipl1- and aurora-related kinase 1) (Aurora-A) (Serine/threonine-protein kinase Ayk1) Length = 395 Score = 40.4 bits (93), Expect(2) = 6e-05 Identities = 29/67 (43%), Positives = 37/67 (55%), Gaps = 1/67 (1%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEI-TYQLDIYSVGVI 485 LL N KIADFG S H SR T+ GTL YL PE G + ++D++S+GV+ Sbjct: 254 LLGSNGELKIADFGWS--VHAPSSRRTTMC--GTLDYLPPEMIEGRMHDEKVDLWSLGVL 309 Query: 484 IIEILTG 464 E L G Sbjct: 310 CYEFLVG 316 Score = 25.8 bits (55), Expect(2) = 6e-05 Identities = 7/18 (38%), Positives = 13/18 (72%) Frame = -2 Query: 707 HQRNILHLDLKPANIFVG 654 H + ++H D+KP N+ +G Sbjct: 239 HSKRVIHRDIKPENLLLG 256
>IRAK3_HUMAN (Q9Y616) Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1)| (IRAK-3) (IL-1 receptor-associated kinase M) (IRAK-M) Length = 596 Score = 46.6 bits (109), Expect = 8e-05 Identities = 22/71 (30%), Positives = 43/71 (60%), Gaps = 5/71 (7%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGT----LGYLAPEFCN-GEITYQLDIYS 497 LLD PK+ DF ++ ++ ++ T+N+ + L Y+ E+ G+++ + D+YS Sbjct: 300 LLDDQFQPKLTDFAMAHFRSHLEHQSCTINMTSSSSKHLWYMPEEYIRQGKLSIKTDVYS 359 Query: 496 VGVIIIEILTG 464 G++I+E+LTG Sbjct: 360 FGIVIMEVLTG 370
>ULK1_HUMAN (O75385) Serine/threonine-protein kinase ULK1 (EC 2.7.11.1)| (Unc-51-like kinase 1) Length = 1050 Score = 38.9 bits (89), Expect(2) = 8e-05 Identities = 23/65 (35%), Positives = 37/65 (56%), Gaps = 1/65 (1%) Frame = -3 Query: 637 KIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGE-ITYQLDIYSVGVIIIEILTGK 461 KIADFG +R +QS + + G+ Y+APE + + D++S+G I+ + LTGK Sbjct: 162 KIADFGFARY---LQSNMMAATLCGSPMYMAPEVIMSQHYDGKADLWSIGTIVYQCLTGK 218 Query: 460 KGYLA 446 + A Sbjct: 219 APFQA 223 Score = 26.9 bits (58), Expect(2) = 8e-05 Identities = 10/18 (55%), Positives = 13/18 (72%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 LH + I+H DLKP NI + Sbjct: 129 LHSKGIIHRDLKPQNILL 146
>ULK2_MOUSE (Q9QY01) Serine/threonine-protein kinase ULK2 (EC 2.7.11.1)| (Unc-51-like kinase 2) (Serine/threonine-protein kinase Unc51.2) Length = 1037 Score = 38.1 bits (87), Expect(2) = 8e-05 Identities = 22/65 (33%), Positives = 35/65 (53%), Gaps = 1/65 (1%) Frame = -3 Query: 637 KIADFGVSRCFHEMQSRAITVNIRGTLGYLAPE-FCNGEITYQLDIYSVGVIIIEILTGK 461 KIADFG +R H S + + G+ Y+APE + + D++S+G +I + L GK Sbjct: 155 KIADFGFARYLH---SNTMAATLCGSPMYMAPEVIMSQHYDAKADLWSIGTVIYQCLVGK 211 Query: 460 KGYLA 446 + A Sbjct: 212 PPFQA 216 Score = 27.7 bits (60), Expect(2) = 8e-05 Identities = 10/20 (50%), Positives = 14/20 (70%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFVGW 651 LH + I+H DLKP NI + + Sbjct: 122 LHSKGIIHRDLKPQNILLSY 141
>IKKA_HUMAN (O15111) Inhibitor of nuclear factor kappa-B kinase alpha subunit| (EC 2.7.11.10) (I kappa-B kinase alpha) (IkBKA) (IKK-alpha) (IKK-A) (IkappaB kinase) (I-kappa-B kinase 1) (IKK1) (Conserved helix-loop-helix ubiquitous kinase) (Nuclear factor N Length = 745 Score = 39.3 bits (90), Expect(2) = 8e-05 Identities = 22/69 (31%), Positives = 38/69 (55%), Gaps = 1/69 (1%) Frame = -3 Query: 652 GNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPE-FCNGEITYQLDIYSVGVIIIE 476 G ++ KI D G ++ ++ ++ + GTL YLAPE F N T +D +S G ++ E Sbjct: 157 GKIIHKIIDLGYAK---DVDQGSLCTSFVGTLQYLAPELFENKPYTATVDYWSFGTMVFE 213 Query: 475 ILTGKKGYL 449 + G + +L Sbjct: 214 CIAGYRPFL 222 Score = 26.6 bits (57), Expect(2) = 8e-05 Identities = 10/16 (62%), Positives = 12/16 (75%) Frame = -2 Query: 710 LHQRNILHLDLKPANI 663 LH+ I+H DLKP NI Sbjct: 135 LHENKIIHRDLKPENI 150
>PKAA_STRCO (P54739) Serine/threonine protein kinase pkaA (EC 2.7.11.1)| Length = 543 Score = 41.6 bits (96), Expect(2) = 8e-05 Identities = 39/161 (24%), Positives = 68/161 (42%), Gaps = 1/161 (0%) Frame = -3 Query: 652 GNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEI-TYQLDIYSVGVIIIE 476 G + P + DFG++R + T GT Y+APE G T +D+Y G+++ E Sbjct: 155 GEMHPMLTDFGIAR-LADSPGLTRTHEFVGTPAYVAPESAEGRPQTSAVDVYGAGILLYE 213 Query: 475 ILTGKKGYLAVDNVVESWSNKLEKSQSDVQLKQVRICAEIGIECTDFNPAKRPGTKNIID 296 ++TG+ + + +E L + I C NP RP +N+ Sbjct: 214 LVTGRPPF-GGGSALEVLHQHLSAEPRRPSTVPDPLWTVIE-RCLRKNPDDRPSAENLAR 271 Query: 295 RLVSLDETDSMGGYIETSAVTSQQAENALEELHQARPKVPG 173 L + E +G + ++ + + + AL A +VPG Sbjct: 272 GLRVVAE--GIGVHANSAQIGAAENVGALLAPDPAPAQVPG 310 Score = 24.3 bits (51), Expect(2) = 8e-05 Identities = 8/17 (47%), Positives = 12/17 (70%) Frame = -2 Query: 707 HQRNILHLDLKPANIFV 657 H ++H DLKPAN+ + Sbjct: 134 HADGVVHRDLKPANVLL 150
>HCK_MACFA (Q95M30) Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK)| (Hemopoietic cell kinase) Length = 503 Score = 40.4 bits (93), Expect(2) = 8e-05 Identities = 26/77 (33%), Positives = 45/77 (58%), Gaps = 2/77 (2%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCN-GEITYQLDIYSVGVI 485 L+ +LV KIADFG++R + + A + + + APE N G T + D++S G++ Sbjct: 365 LVSASLVCKIADFGLARIIEDNEYTA-REGAKFPIKWTAPEAINFGSSTIKSDVWSFGIL 423 Query: 484 IIEILT-GKKGYLAVDN 437 ++EI+T G+ Y + N Sbjct: 424 LMEIVTYGRIPYPGMSN 440 Score = 25.4 bits (54), Expect(2) = 8e-05 Identities = 10/18 (55%), Positives = 13/18 (72%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 + QRN +H DL+ ANI V Sbjct: 349 IEQRNYIHRDLRAANILV 366
>PKN2_CORGL (Q8NU97) Serine/threonine protein kinases pknA (EC 2.7.11.1)| Length = 469 Score = 42.4 bits (98), Expect(2) = 8e-05 Identities = 25/77 (32%), Positives = 43/77 (55%), Gaps = 1/77 (1%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNG-EITYQLDIYSVGVI 485 L+ N + KI DFG+++ + T + GT Y++PE G E+T DIYS+GV+ Sbjct: 155 LITANGIVKITDFGIAKAAAAVPLTR-TGMVVGTAQYVSPEQAQGKEVTAASDIYSLGVV 213 Query: 484 IIEILTGKKGYLAVDNV 434 E++ G++ + +V Sbjct: 214 GYEMMAGRRPFTGDSSV 230 Score = 23.5 bits (49), Expect(2) = 8e-05 Identities = 6/18 (33%), Positives = 14/18 (77%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 +H+ +++H D+KP N+ + Sbjct: 139 IHRMDMVHRDIKPGNMLI 156
>KPK1_ARATH (P42818) Serine/threonine-protein kinase AtPK1/AtPK6 (EC 2.7.11.1)| Length = 465 Score = 38.1 bits (87), Expect(2) = 8e-05 Identities = 24/70 (34%), Positives = 42/70 (60%), Gaps = 1/70 (1%) Frame = -3 Query: 655 DGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGE-ITYQLDIYSVGVIII 479 DG+++ + DFG+++ F E + ++ GT Y+APE G+ D +SVG+++ Sbjct: 268 DGHVM--LTDFGLAKEFEE---NTRSNSMCGTTEYMAPEIVRGKGHDKAADWWSVGILLY 322 Query: 478 EILTGKKGYL 449 E+LTGK +L Sbjct: 323 EMLTGKPPFL 332 Score = 27.7 bits (60), Expect(2) = 8e-05 Identities = 10/18 (55%), Positives = 14/18 (77%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 LH++ I+H DLKP NI + Sbjct: 248 LHEKGIMHRDLKPENILM 265
>PKN5_MYXXA (P54737) Serine/threonine-protein kinase pkn5 (EC 2.7.11.1)| Length = 380 Score = 40.4 bits (93), Expect(2) = 8e-05 Identities = 26/86 (30%), Positives = 47/86 (54%), Gaps = 1/86 (1%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGE-ITYQLDIYSVGVI 485 ++D + ++ DFG+++ + + + GT Y+APE GE + + D+YS+GVI Sbjct: 251 MVDDDRQVRLMDFGLAKFLADDAAITEAGKLVGTYRYMAPEQILGEPLDGRADLYSLGVI 310 Query: 484 IIEILTGKKGYLAVDNVVESWSNKLE 407 + E+L+G+ + A E W LE Sbjct: 311 LYELLSGRPPFDA-KTPHELWRQVLE 335 Score = 25.4 bits (54), Expect(2) = 8e-05 Identities = 9/18 (50%), Positives = 13/18 (72%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 +H ++H DLKP+NI V Sbjct: 235 IHGHGLVHRDLKPSNIMV 252
>CDC2_CHICK (P13863) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 38.9 bits (89), Expect(2) = 8e-05 Identities = 27/69 (39%), Positives = 38/69 (55%), Gaps = 2/69 (2%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEITYQ--LDIYSVGV 488 L+D V K+ADFG++R F + R T + TL Y +PE G Y +DI+S+G Sbjct: 135 LIDDKGVIKLADFGLARAF-GIPVRVYTHEV-VTLWYRSPEVLLGSALYSTPVDIWSIGT 192 Query: 487 IIIEILTGK 461 I E+ T K Sbjct: 193 IFAELATKK 201 Score = 26.9 bits (58), Expect(2) = 8e-05 Identities = 9/17 (52%), Positives = 12/17 (70%) Frame = -2 Query: 707 HQRNILHLDLKPANIFV 657 H R +LH DLKP N+ + Sbjct: 120 HSRRVLHRDLKPQNLLI 136
>SRC42_DROME (Q9V9J3) Tyrosine-protein kinase Src42A (EC 2.7.10.2) (Dsrc41)| Length = 517 Score = 46.2 bits (108), Expect = 1e-04 Identities = 37/119 (31%), Positives = 63/119 (52%), Gaps = 6/119 (5%) Frame = -3 Query: 655 DGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCN-GEITYQLDIYSVGVIII 479 DGN+V KIADFG++R E + A V R + + APE N + + + D++S G+++ Sbjct: 380 DGNIV-KIADFGLARLIKEDEYEA-RVGARFPIKWTAPEAANYSKFSIKSDVWSFGILLT 437 Query: 478 EILT-GKKGYLAVDNVVESWSNKLEKSQSDVQLKQVRICA----EIGIECTDFNPAKRP 317 E++T G+ Y + N + L + + ++ Q C EI +EC +P +RP Sbjct: 438 ELVTYGRIPYPGMTN-----AEVLTQVEHGYRMPQPPNCEPRLYEIMLECWHKDPMRRP 491
>ULK2_HUMAN (Q8IYT8) Serine/threonine-protein kinase ULK2 (EC 2.7.11.1)| (Unc-51-like kinase 2) Length = 1036 Score = 37.7 bits (86), Expect(2) = 1e-04 Identities = 22/65 (33%), Positives = 35/65 (53%), Gaps = 1/65 (1%) Frame = -3 Query: 637 KIADFGVSRCFHEMQSRAITVNIRGTLGYLAPE-FCNGEITYQLDIYSVGVIIIEILTGK 461 KIADFG +R H S + + G+ Y+APE + + D++S+G +I + L GK Sbjct: 155 KIADFGFARYLH---SNMMAATLCGSPMYMAPEVIMSQHYDAKADLWSIGTVIYQCLVGK 211 Query: 460 KGYLA 446 + A Sbjct: 212 PPFQA 216 Score = 27.7 bits (60), Expect(2) = 1e-04 Identities = 10/20 (50%), Positives = 14/20 (70%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFVGW 651 LH + I+H DLKP NI + + Sbjct: 122 LHSKGIIHRDLKPQNILLSY 141
>KPCD1_MOUSE (Q62101) Serine/threonine-protein kinase D1 (EC 2.7.11.13)| (nPKC-D1) (Protein kinase D) (Protein kinase C mu type) (nPKC-mu) Length = 918 Score = 37.7 bits (86), Expect(2) = 1e-04 Identities = 26/59 (44%), Positives = 31/59 (52%), Gaps = 1/59 (1%) Frame = -3 Query: 637 KIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFC-NGEITYQLDIYSVGVIIIEILTG 464 K+ DFG +R E R V GT YLAPE N LD++SVGVII L+G Sbjct: 730 KLCDFGFARIIGEKSFRRSVV---GTPAYLAPEVLRNKGYNRSLDMWSVGVIIYVSLSG 785 Score = 27.7 bits (60), Expect(2) = 1e-04 Identities = 10/18 (55%), Positives = 14/18 (77%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 LH +NI+H DLKP N+ + Sbjct: 703 LHFKNIVHCDLKPENVLL 720
>KPCD1_HUMAN (Q15139) Serine/threonine-protein kinase D1 (EC 2.7.11.13)| (nPKC-D1) (Protein kinase D) (Protein kinase C mu type) (nPKC-mu) Length = 912 Score = 37.7 bits (86), Expect(2) = 1e-04 Identities = 26/59 (44%), Positives = 31/59 (52%), Gaps = 1/59 (1%) Frame = -3 Query: 637 KIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFC-NGEITYQLDIYSVGVIIIEILTG 464 K+ DFG +R E R V GT YLAPE N LD++SVGVII L+G Sbjct: 724 KLCDFGFARIIGEKSFRRSVV---GTPAYLAPEVLRNKGYNRSLDMWSVGVIIYVSLSG 779 Score = 27.7 bits (60), Expect(2) = 1e-04 Identities = 10/18 (55%), Positives = 14/18 (77%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 LH +NI+H DLKP N+ + Sbjct: 697 LHFKNIVHCDLKPENVLL 714
>PKNH_MYCTU (Q11053) Probable serine/threonine-protein kinase pknH (EC| 2.7.11.1) Length = 626 Score = 42.7 bits (99), Expect(2) = 1e-04 Identities = 23/64 (35%), Positives = 37/64 (57%), Gaps = 1/64 (1%) Frame = -3 Query: 634 IADFGVSRCFHEMQSRAITVNIRGTLGYLAPE-FCNGEITYQLDIYSVGVIIIEILTGKK 458 + DFG++ + + + + GT Y+APE F N E+TY+ DIY++ ++ E LTG Sbjct: 155 LVDFGIASATTDEKLTQLGTAV-GTWKYMAPERFSNDEVTYRADIYALACVLHECLTGAP 213 Query: 457 GYLA 446 Y A Sbjct: 214 PYRA 217 Score = 22.7 bits (47), Expect(2) = 1e-04 Identities = 7/17 (41%), Positives = 11/17 (64%) Frame = -2 Query: 707 HQRNILHLDLKPANIFV 657 H ++H D+KP NI + Sbjct: 131 HADGVMHRDVKPQNILI 147
>PKNH_MYCBO (Q7U095) Probable serine/threonine-protein kinase pknH (EC| 2.7.11.1) Length = 596 Score = 42.7 bits (99), Expect(2) = 1e-04 Identities = 23/64 (35%), Positives = 37/64 (57%), Gaps = 1/64 (1%) Frame = -3 Query: 634 IADFGVSRCFHEMQSRAITVNIRGTLGYLAPE-FCNGEITYQLDIYSVGVIIIEILTGKK 458 + DFG++ + + + + GT Y+APE F N E+TY+ DIY++ ++ E LTG Sbjct: 155 LVDFGIASATTDEKLTQLGTAV-GTWKYMAPERFSNDEVTYRADIYALACVLHECLTGAP 213 Query: 457 GYLA 446 Y A Sbjct: 214 PYRA 217 Score = 22.7 bits (47), Expect(2) = 1e-04 Identities = 7/17 (41%), Positives = 11/17 (64%) Frame = -2 Query: 707 HQRNILHLDLKPANIFV 657 H ++H D+KP NI + Sbjct: 131 HADGVMHRDVKPQNILI 147
>FYN_XIPHE (P27446) Proto-oncogene tyrosine-protein kinase FYN (EC 2.7.10.2)| (P59-FYN) Length = 536 Score = 41.6 bits (96), Expect(2) = 1e-04 Identities = 33/121 (27%), Positives = 62/121 (51%), Gaps = 6/121 (4%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFC-NGEITYQLDIYSVGVI 485 L+ NLV KIADFG++R + + A + + + APE G T + D++S G++ Sbjct: 396 LVGDNLVCKIADFGLARLIEDNEYTA-RQGAKFPIKWTAPEAALYGRFTIKSDVWSFGIL 454 Query: 484 IIEILT-GKKGYLAVDNVVESWSNKLEKSQSDVQLKQVRICA----EIGIECTDFNPAKR 320 + E++T G+ Y ++N LE+ + ++ + C E+ ++C +P +R Sbjct: 455 LTELVTKGRVPYPGMNN-----REVLEQVERGYRMPCPQDCPASLHELMLQCWKKDPEER 509 Query: 319 P 317 P Sbjct: 510 P 510 Score = 23.9 bits (50), Expect(2) = 1e-04 Identities = 9/19 (47%), Positives = 13/19 (68%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFVG 654 + + N +H DL+ ANI VG Sbjct: 380 IERMNYIHRDLRSANILVG 398
>NRKA_TRYBB (Q08942) Putative serine/threonine-protein kinase A (EC 2.7.11.1)| Length = 431 Score = 42.7 bits (99), Expect(2) = 1e-04 Identities = 25/73 (34%), Positives = 39/73 (53%), Gaps = 1/73 (1%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGE-ITYQLDIYSVGVI 485 LL + K+ DFG S + + S + GT YLAPE N + + D++S+GV+ Sbjct: 154 LLTSTGLVKLGDFGFSHQYEDTVSGVVASTFCGTPYYLAPELWNNKRYNKKADVWSLGVL 213 Query: 484 IIEILTGKKGYLA 446 + EI+ KK + A Sbjct: 214 LYEIMGMKKPFSA 226 Score = 22.7 bits (47), Expect(2) = 1e-04 Identities = 7/18 (38%), Positives = 12/18 (66%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 +H +LH D+K AN+ + Sbjct: 138 IHSHKMLHRDIKSANVLL 155
>PHKG2_MOUSE (Q9DB30) Phosphorylase b kinase gamma catalytic chain, testis/liver| isoform (EC 2.7.11.19) (PHK-gamma-T) (Phosphorylase kinase gamma subunit 2) Length = 406 Score = 37.7 bits (86), Expect(2) = 1e-04 Identities = 26/73 (35%), Positives = 42/73 (57%), Gaps = 7/73 (9%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEF--CNGEITY-----QLDI 503 LLD N+ +++DFG S C E + + GT GYLAPE C+ + T+ ++D+ Sbjct: 160 LLDDNMQIRLSDFGFS-CHLEAGEK--LRELCGTPGYLAPEILKCSMDETHPGYGKEVDL 216 Query: 502 YSVGVIIIEILTG 464 ++ GVI+ +L G Sbjct: 217 WACGVILFTLLAG 229 Score = 27.7 bits (60), Expect(2) = 1e-04 Identities = 11/18 (61%), Positives = 13/18 (72%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 LH NI+H DLKP NI + Sbjct: 144 LHANNIVHRDLKPENILL 161
>CCRK_RAT (Q4KM34) Cell cycle-related kinase (EC 2.7.11.22)| Length = 346 Score = 37.4 bits (85), Expect(2) = 1e-04 Identities = 24/60 (40%), Positives = 33/60 (55%), Gaps = 2/60 (3%) Frame = -3 Query: 637 KIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEITYQ--LDIYSVGVIIIEILTG 464 KIADFG++R F R T + T Y APE G Y +D+++VG I+ E+L G Sbjct: 142 KIADFGLARVFSPDGGRLYTHQV-ATRWYRAPELLYGARQYDQGVDLWAVGCIMGELLNG 200 Score = 28.1 bits (61), Expect(2) = 1e-04 Identities = 10/17 (58%), Positives = 13/17 (76%) Frame = -2 Query: 707 HQRNILHLDLKPANIFV 657 H NI+H DLKPAN+ + Sbjct: 119 HANNIVHRDLKPANLLI 135
>CCRK_MOUSE (Q9JHU3) Cell cycle-related kinase (EC 2.7.11.22)| (Cyclin-kinase-activating kinase p42) (CDK-activating kinase p42) (CAK-kinase p42) (CDK-related protein kinase PNQLARE) Length = 346 Score = 37.4 bits (85), Expect(2) = 1e-04 Identities = 24/60 (40%), Positives = 33/60 (55%), Gaps = 2/60 (3%) Frame = -3 Query: 637 KIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEITYQ--LDIYSVGVIIIEILTG 464 KIADFG++R F R T + T Y APE G Y +D+++VG I+ E+L G Sbjct: 142 KIADFGLARVFSPDGGRLYTHQV-ATRWYRAPELLYGARQYDQGVDLWAVGCIMGELLNG 200 Score = 28.1 bits (61), Expect(2) = 1e-04 Identities = 10/17 (58%), Positives = 13/17 (76%) Frame = -2 Query: 707 HQRNILHLDLKPANIFV 657 H NI+H DLKPAN+ + Sbjct: 119 HANNIVHRDLKPANLLI 135
>CC2H3_TRYBB (P54666) Cell division control protein 2 homolog 3 (EC 2.7.11.22)| Length = 311 Score = 37.7 bits (86), Expect(2) = 1e-04 Identities = 25/61 (40%), Positives = 35/61 (57%), Gaps = 2/61 (3%) Frame = -3 Query: 637 KIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEITY--QLDIYSVGVIIIEILTG 464 KIADFG++R F ++ T + TL Y APE GE Y +D++S+G I E+ G Sbjct: 160 KIADFGLARAF-QIPMHTYTHEV-VTLWYRAPEILLGEKHYTPAVDMWSIGCIFAELARG 217 Query: 463 K 461 K Sbjct: 218 K 218 Score = 27.7 bits (60), Expect(2) = 1e-04 Identities = 11/17 (64%), Positives = 13/17 (76%) Frame = -2 Query: 707 HQRNILHLDLKPANIFV 657 H+ I+H DLKPANI V Sbjct: 137 HRHRIVHRDLKPANILV 153
>CDC2_ORYLU (Q9DG98) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 38.1 bits (87), Expect(2) = 1e-04 Identities = 27/69 (39%), Positives = 37/69 (53%), Gaps = 2/69 (2%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEITYQ--LDIYSVGV 488 L+D V K+ADFG++R F + R T + TL Y APE G Y +D++S G Sbjct: 135 LIDNKGVIKLADFGLARAF-GVPVRVYTHEV-VTLWYRAPEVLLGSPRYSTPVDVWSTGT 192 Query: 487 IIIEILTGK 461 I E+ T K Sbjct: 193 IFAELATKK 201 Score = 27.3 bits (59), Expect(2) = 1e-04 Identities = 9/17 (52%), Positives = 13/17 (76%) Frame = -2 Query: 707 HQRNILHLDLKPANIFV 657 H+R +LH DLKP N+ + Sbjct: 120 HRRRVLHRDLKPQNLLI 136
>CDC2_ORYLA (Q9DGD3) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 38.1 bits (87), Expect(2) = 1e-04 Identities = 27/69 (39%), Positives = 37/69 (53%), Gaps = 2/69 (2%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEITYQ--LDIYSVGV 488 L+D V K+ADFG++R F + R T + TL Y APE G Y +D++S G Sbjct: 135 LIDNKGVIKLADFGLARAF-GVPVRVYTHEV-VTLWYRAPEVLLGSPRYSTPVDVWSTGT 192 Query: 487 IIIEILTGK 461 I E+ T K Sbjct: 193 IFAELATKK 201 Score = 27.3 bits (59), Expect(2) = 1e-04 Identities = 9/17 (52%), Positives = 13/17 (76%) Frame = -2 Query: 707 HQRNILHLDLKPANIFV 657 H+R +LH DLKP N+ + Sbjct: 120 HRRRVLHRDLKPQNLLI 136
>CDC2_ORYJA (Q9DGA2) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 38.1 bits (87), Expect(2) = 1e-04 Identities = 27/69 (39%), Positives = 37/69 (53%), Gaps = 2/69 (2%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEITYQ--LDIYSVGV 488 L+D V K+ADFG++R F + R T + TL Y APE G Y +D++S G Sbjct: 135 LIDNKGVIKLADFGLARAF-GVPVRVYTHEV-VTLWYRAPEVLLGSPRYSTPVDVWSTGT 192 Query: 487 IIIEILTGK 461 I E+ T K Sbjct: 193 IFAELATKK 201 Score = 27.3 bits (59), Expect(2) = 1e-04 Identities = 9/17 (52%), Positives = 13/17 (76%) Frame = -2 Query: 707 HQRNILHLDLKPANIFV 657 H+R +LH DLKP N+ + Sbjct: 120 HRRRVLHRDLKPQNLLI 136
>GCN2_YEAST (P15442) Serine/threonine-protein kinase GCN2 (EC 2.7.11.1)| Length = 1590 Score = 36.2 bits (82), Expect(2) = 1e-04 Identities = 31/129 (24%), Positives = 60/129 (46%), Gaps = 15/129 (11%) Frame = -3 Query: 637 KIADFGVSRCFHEM-------------QSRAITVNIRGTLGYLAPEFCNGEITY--QLDI 503 KI DFG+++ H S +T I GT Y+A E +G Y ++D+ Sbjct: 781 KIGDFGLAKNVHRSLDILKLDSQNLPGSSDNLTSAI-GTAMYVATEVLDGTGHYNEKIDM 839 Query: 502 YSVGVIIIEILTGKKGYLAVDNVVESWSNKLEKSQSDVQLKQVRICAEIGIECTDFNPAK 323 YS+G+I E++ + N+++ + + D ++++ +I D +P K Sbjct: 840 YSLGIIFFEMIYPFSTGMERVNILKKLRSVSIEFPPDFDDNKMKVEKKIIRLLIDHDPNK 899 Query: 322 RPGTKNIID 296 RPG + +++ Sbjct: 900 RPGARTLLN 908 Score = 28.9 bits (63), Expect(2) = 1e-04 Identities = 10/18 (55%), Positives = 14/18 (77%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 +H + I+H DLKP NIF+ Sbjct: 757 IHSQGIIHRDLKPMNIFI 774
>PHY1_CERPU (P25848) Light-sensor Protein kinase [Includes: Phytochrome; Protein| kinase (EC 2.7.11.1)] Length = 1307 Score = 39.3 bits (90), Expect(2) = 1e-04 Identities = 35/132 (26%), Positives = 56/132 (42%), Gaps = 16/132 (12%) Frame = -3 Query: 637 KIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCN-------GEITY---------QLD 506 K+ADFG+S+ + RGT ++APE N GEI++ + D Sbjct: 1151 KVADFGLSKTKDSSTRYSNQTWNRGTNRWMAPEVINLGYESTEGEISFDGKVPKYPLKSD 1210 Query: 505 IYSVGVIIIEILTGKKGYLAVDNVVESWSNKLEKSQSDVQLKQVRICAEIGIECTDFNPA 326 +YS G++ E+LTG + N LE + D+ + +C + +P Sbjct: 1211 VYSFGMVCYEVLTGDVPFPEEKNPNNVKRMVLEGVRPDLPAHCPIELKALITDCWNQDPL 1270 Query: 325 KRPGTKNIIDRL 290 KRP I +L Sbjct: 1271 KRPSFAVICQKL 1282 Score = 25.8 bits (55), Expect(2) = 1e-04 Identities = 10/18 (55%), Positives = 13/18 (72%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 LH++ I+H DLK NI V Sbjct: 1118 LHEKGIIHRDLKSMNILV 1135
>MYLK_RABIT (P29294) Myosin light chain kinase, smooth muscle (EC 2.7.11.18)| (MLCK) [Contains: Telokin] Length = 1147 Score = 37.4 bits (85), Expect(2) = 1e-04 Identities = 25/75 (33%), Positives = 43/75 (57%), Gaps = 1/75 (1%) Frame = -3 Query: 637 KIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGE-ITYQLDIYSVGVIIIEILTGK 461 K+ DFG++R S + + GT ++APE N E I+Y D++S+GVI +++G Sbjct: 834 KLIDFGLARRLENAGSLKV---LFGTPEFVAPEVINYEPISYATDMWSIGVICYILVSGL 890 Query: 460 KGYLAVDNVVESWSN 416 ++ DN E+ +N Sbjct: 891 SPFMG-DNDNETLAN 904 Score = 27.7 bits (60), Expect(2) = 1e-04 Identities = 10/16 (62%), Positives = 14/16 (87%) Frame = -2 Query: 710 LHQRNILHLDLKPANI 663 +H++ I+HLDLKP NI Sbjct: 808 IHKQGIVHLDLKPENI 823
>FGFR1_XENLA (P22182) Fibroblast growth factor receptor 1 precursor (EC 2.7.10.1)| (FGFR-1) Length = 812 Score = 45.8 bits (107), Expect = 1e-04 Identities = 41/150 (27%), Positives = 69/150 (46%), Gaps = 2/150 (1%) Frame = -3 Query: 670 RTYLLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEI-TYQLDIYSV 494 R L+ + + KIADFG++R H + T N R + ++APE I T+Q D++S Sbjct: 621 RNVLVTEDNIMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSF 680 Query: 493 GVIIIEILT-GKKGYLAVDNVVESWSNKLEKSQSDVQLKQVRICAEIGIECTDFNPAKRP 317 GV++ EI T G Y V + E + E + D + +C P++RP Sbjct: 681 GVLLWEIFTLGGSPYPGVP-MEELFKLLKEGHRMDKPTNCTNELYMMMKDCWHAMPSQRP 739 Query: 316 GTKNIIDRLVSLDETDSMGGYIETSAVTSQ 227 +++ L + S Y++ S +Q Sbjct: 740 TFNQLVEDLDRILALSSNQEYLDLSMPVNQ 769
>CEK3_CHICK (P18461) Tyrosine kinase receptor CEK3 precursor (EC 2.7.10.1)| Length = 823 Score = 45.8 bits (107), Expect = 1e-04 Identities = 43/153 (28%), Positives = 72/153 (47%), Gaps = 5/153 (3%) Frame = -3 Query: 670 RTYLLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEI-TYQLDIYSV 494 R L+ N V KIADFG++R + + T N R + ++APE + T+Q D++S Sbjct: 632 RNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSF 691 Query: 493 GVIIIEILT-GKKGYLAVDNVVESWSNKLEKSQSDVQLKQVRICAEIGIECTDFNPAKRP 317 GV++ EI T G Y + V E + E + D + +C P++RP Sbjct: 692 GVLMWEIFTLGGSPYPGIP-VEELFKLLKEGHRMDKPANCTNELYMMMRDCWQAVPSQRP 750 Query: 316 GTKNII---DRLVSLDETDSMGGYIETSAVTSQ 227 K ++ DR+++L + Y++ S Q Sbjct: 751 TFKQLVEDLDRILTLTTNEE---YLDLSGPLEQ 780
>FGFR1_RAT (Q04589) Basic fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) (FGFR-1) (bFGF-R) (MFR) Length = 822 Score = 45.8 bits (107), Expect = 1e-04 Identities = 41/151 (27%), Positives = 68/151 (45%), Gaps = 1/151 (0%) Frame = -3 Query: 670 RTYLLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEI-TYQLDIYSV 494 R L+ + V KIADFG++R H + T N R + ++APE I T+Q D++S Sbjct: 627 RNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSF 686 Query: 493 GVIIIEILTGKKGYLAVDNVVESWSNKLEKSQSDVQLKQVRICAEIGIECTDFNPAKRPG 314 GV++ EI T V E + E + D + +C + P++RP Sbjct: 687 GVLLWEIFTLGGSPNPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWNAVPSQRPT 746 Query: 313 TKNIIDRLVSLDETDSMGGYIETSAVTSQQA 221 K +++ L + S Y++ S Q + Sbjct: 747 FKQLVEDLDRIVALTSNQEYLDLSMPLDQDS 777
>FGFR2_MOUSE (P21803) Fibroblast growth factor receptor 2 precursor (EC 2.7.10.1)| (FGFR-2) (Keratinocyte growth factor receptor) Length = 821 Score = 45.8 bits (107), Expect = 1e-04 Identities = 47/175 (26%), Positives = 78/175 (44%), Gaps = 5/175 (2%) Frame = -3 Query: 670 RTYLLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEI-TYQLDIYSV 494 R L+ N V KIADFG++R + + T N R + ++APE + T+Q D++S Sbjct: 630 RNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSF 689 Query: 493 GVIIIEILT-GKKGYLAVDNVVESWSNKLEKSQSDVQLKQVRICAEIGIECTDFNPAKRP 317 GV++ EI T G Y + V E + E + D + +C P++RP Sbjct: 690 GVLMWEIFTLGGSPYPGIP-VEELFKLLKEGHRMDKPTNCTNELYMMMRDCWHAVPSQRP 748 Query: 316 GTKNII---DRLVSLDETDSMGGYIETSAVTSQQAENALEELHQARPKVPGEISS 161 K ++ DR+++L T+++ + + L Q P P SS Sbjct: 749 TFKQLVEDLDRILTL--------------TTNEEYLDLTQPLEQYSPSYPDTSSS 789
>KPCD3_HUMAN (O94806) Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein| kinase C nu type) (nPKC-nu) (Protein kinase EPK2) Length = 890 Score = 37.4 bits (85), Expect(2) = 1e-04 Identities = 25/59 (42%), Positives = 31/59 (52%), Gaps = 1/59 (1%) Frame = -3 Query: 637 KIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGE-ITYQLDIYSVGVIIIEILTG 464 K+ DFG +R E R V GT YLAPE + LD++SVGVII L+G Sbjct: 717 KLCDFGFARIIGEKSFRRSVV---GTPAYLAPEVLRSKGYNRSLDMWSVGVIIYVSLSG 772 Score = 27.7 bits (60), Expect(2) = 1e-04 Identities = 10/18 (55%), Positives = 14/18 (77%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 LH +NI+H DLKP N+ + Sbjct: 690 LHFKNIVHCDLKPENVLL 707
>PKND_MYCTU (O05871) Serine/threonine-protein kinase pknD (EC 2.7.11.1)| Length = 664 Score = 42.4 bits (98), Expect(2) = 1e-04 Identities = 24/64 (37%), Positives = 35/64 (54%), Gaps = 1/64 (1%) Frame = -3 Query: 634 IADFGVSRCFHEMQSRAITVNIRGTLGYLAPE-FCNGEITYQLDIYSVGVIIIEILTGKK 458 + DFG++R + T GT Y+APE F E+TY+ DIY++ ++ E LTG Sbjct: 154 LVDFGIARAASD-PGLTQTGTAVGTYNYMAPERFTGDEVTYRADIYALACVLGECLTGAP 212 Query: 457 GYLA 446 Y A Sbjct: 213 PYRA 216 Score = 22.7 bits (47), Expect(2) = 1e-04 Identities = 8/17 (47%), Positives = 10/17 (58%) Frame = -2 Query: 707 HQRNILHLDLKPANIFV 657 H + H D+KP NI V Sbjct: 130 HANGVTHRDVKPENILV 146
>CDPK4_PLAYO (Q7RJG2) Calcium-dependent protein kinase 4 (EC 2.7.11.1)| Length = 527 Score = 37.7 bits (86), Expect(2) = 1e-04 Identities = 21/62 (33%), Positives = 35/62 (56%) Frame = -3 Query: 649 NLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEITYQLDIYSVGVIIIEIL 470 +++ KI DFG+S F + + GT Y+AP+ +G + DI+S GVI+ +L Sbjct: 207 DMIIKIIDFGLSTHFEYSKKMKDKI---GTAYYIAPDVLHGTYDEKCDIWSCGVILYILL 263 Query: 469 TG 464 +G Sbjct: 264 SG 265 Score = 27.3 bits (59), Expect(2) = 1e-04 Identities = 9/18 (50%), Positives = 14/18 (77%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 +H+ N++H DLKP NI + Sbjct: 183 MHKNNVVHRDLKPENILL 200
>CDPK4_PLAF7 (Q8IBS5) Calcium-dependent protein kinase 4 (EC 2.7.11.1)| Length = 527 Score = 37.7 bits (86), Expect(2) = 1e-04 Identities = 21/62 (33%), Positives = 35/62 (56%) Frame = -3 Query: 649 NLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEITYQLDIYSVGVIIIEIL 470 +++ KI DFG+S F + + GT Y+AP+ +G + DI+S GVI+ +L Sbjct: 207 DMIIKIIDFGLSTHFEYSKKMKDKI---GTAYYIAPDVLHGTYDEKCDIWSCGVILYILL 263 Query: 469 TG 464 +G Sbjct: 264 SG 265 Score = 27.3 bits (59), Expect(2) = 1e-04 Identities = 9/18 (50%), Positives = 14/18 (77%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 +H+ N++H DLKP NI + Sbjct: 183 MHKNNVVHRDLKPENILL 200
>CDPK4_PLABA (P62345) Calcium-dependent protein kinase 4 (EC 2.7.11.1) (PbCDPK4)| Length = 527 Score = 37.7 bits (86), Expect(2) = 1e-04 Identities = 21/62 (33%), Positives = 35/62 (56%) Frame = -3 Query: 649 NLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEITYQLDIYSVGVIIIEIL 470 +++ KI DFG+S F + + GT Y+AP+ +G + DI+S GVI+ +L Sbjct: 207 DMIIKIIDFGLSTHFEYSKKMKDKI---GTAYYIAPDVLHGTYDEKCDIWSCGVILYILL 263 Query: 469 TG 464 +G Sbjct: 264 SG 265 Score = 27.3 bits (59), Expect(2) = 1e-04 Identities = 9/18 (50%), Positives = 14/18 (77%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 +H+ N++H DLKP NI + Sbjct: 183 MHKNNVVHRDLKPENILL 200
>PKN2_COREF (Q8FUI4) Serine/threonine protein kinases drp72 (EC 2.7.11.1)| Length = 520 Score = 41.6 bits (96), Expect(2) = 1e-04 Identities = 24/77 (31%), Positives = 44/77 (57%), Gaps = 1/77 (1%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNG-EITYQLDIYSVGVI 485 L+ N + KI DFG+++ + T + GT Y++PE G ++T D+YS+GV+ Sbjct: 155 LITANGILKITDFGIAKAAASVPLTR-TGMVVGTAQYVSPEQAQGHQVTPASDVYSLGVV 213 Query: 484 IIEILTGKKGYLAVDNV 434 E+L+G++ + +V Sbjct: 214 GYEMLSGRRPFTGDSSV 230 Score = 23.5 bits (49), Expect(2) = 1e-04 Identities = 6/18 (33%), Positives = 13/18 (72%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 +H+ ++H D+KP N+ + Sbjct: 139 IHRMGLVHRDIKPGNMLI 156
>SRK1_SPOLA (P42686) Tyrosine-protein kinase isoform SRK1 (EC 2.7.10.2)| Length = 505 Score = 41.2 bits (95), Expect(2) = 1e-04 Identities = 41/151 (27%), Positives = 71/151 (47%), Gaps = 6/151 (3%) Frame = -3 Query: 670 RTYLLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFC-NGEITYQLDIYSV 494 R L+ + + K+ADFG++R E A T + + + APE T + D++S Sbjct: 363 RNILVGEHGICKVADFGLARVIDEEIYEAHT-GAKFPIKWTAPEAAMYNRFTIKSDVWSF 421 Query: 493 GVIIIEILT-GKKGYLAVDNVVESWSNKLEKSQSDVQLKQVRICA----EIGIECTDFNP 329 GV++ EI+T G+ Y + N LEK Q + ++ C +I ++C +P Sbjct: 422 GVVLYEIITYGRFPYPGMTN-----PEVLEKIQQNYRMPCPANCPKQFHDIMLDCWREDP 476 Query: 328 AKRPGTKNIIDRLVSLDETDSMGGYIETSAV 236 A RP + + L+E + GY + A+ Sbjct: 477 ASRPTFETL---QWQLEEFFNSEGYRDPDAI 504 Score = 23.9 bits (50), Expect(2) = 1e-04 Identities = 10/19 (52%), Positives = 12/19 (63%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFVG 654 L Q+N +H DL NI VG Sbjct: 350 LEQQNYIHRDLAARNILVG 368
>MKC1_CANAL (P43068) Mitogen-activated protein kinase MKC1 (EC 2.7.11.24) (MAP| kinase MKC1) Length = 501 Score = 38.5 bits (88), Expect(2) = 1e-04 Identities = 36/145 (24%), Positives = 64/145 (44%), Gaps = 17/145 (11%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEM--QSRAITVNIRGTLGYLAPEFCNGEITYQ--LDIYSV 494 L++ + KI DFG++R F E ++ T Y APE Y +DI+SV Sbjct: 181 LVNADCELKICDFGLARGFSENPDENAGFMTEYVATRWYRAPEIMLSFTNYTKAIDIWSV 240 Query: 493 GVIIIEILTGKKGYLAVDNV-------------VESWSNKLEKSQSDVQLKQVRICAEIG 353 G I+ E+L GK + D V ES ++ ++ ++ + I + Sbjct: 241 GCILAELLGGKPLFRGKDYVDQLNQILMILGTPPESTLQRIGSHRAQNYVRSLPITRKAS 300 Query: 352 IECTDFNPAKRPGTKNIIDRLVSLD 278 E + P P ++++R+++LD Sbjct: 301 YE--ELFPDANPLALDLLERMLTLD 323 Score = 26.6 bits (57), Expect(2) = 1e-04 Identities = 9/18 (50%), Positives = 13/18 (72%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 +H ++LH DLKP N+ V Sbjct: 165 IHSADVLHRDLKPGNLLV 182
>RIPK3_RAT (Q9Z2P5) Receptor-interacting serine/threonine-protein kinase 3 (EC| 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) (Homocysteine respondent protein HCYP2) Length = 478 Score = 41.6 bits (96), Expect(2) = 1e-04 Identities = 28/72 (38%), Positives = 42/72 (58%), Gaps = 4/72 (5%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVN--IRGTLGYLAPEFCN--GEITYQLDIYSV 494 LLD L K+ADFG+S QS + + + GTL YLAPE + G+ + D+YS Sbjct: 150 LLDLELHAKLADFGLSTFQGGSQSGSGSGSRDSGGTLAYLAPELLDNDGKASKASDVYSF 209 Query: 493 GVIIIEILTGKK 458 GV++ +L G++ Sbjct: 210 GVLVWTVLAGRE 221 Score = 23.5 bits (49), Expect(2) = 1e-04 Identities = 11/26 (42%), Positives = 16/26 (61%), Gaps = 2/26 (7%) Frame = -2 Query: 710 LHQRN--ILHLDLKPANIFVGWQFGA 639 LH N +LH DLKP+N+ + + A Sbjct: 132 LHSLNPSLLHRDLKPSNVLLDLELHA 157
>NRKB_TRYBB (Q03428) Putative serine/threonine-protein kinase B (EC 2.7.11.1)| Length = 431 Score = 42.4 bits (98), Expect(2) = 1e-04 Identities = 25/73 (34%), Positives = 38/73 (52%), Gaps = 1/73 (1%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNG-EITYQLDIYSVGVI 485 LL + K+ DFG S + + S + GT YLAPE N + D++S+GV+ Sbjct: 154 LLTSTGLVKLGDFGFSHQYEDTVSGVVASTFCGTPYYLAPELWNNLRYNKKADVWSLGVL 213 Query: 484 IIEILTGKKGYLA 446 + EI+ KK + A Sbjct: 214 LYEIMGMKKPFSA 226 Score = 22.7 bits (47), Expect(2) = 1e-04 Identities = 7/18 (38%), Positives = 12/18 (66%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 +H +LH D+K AN+ + Sbjct: 138 IHSHKMLHRDIKSANVLL 155
>PHKG2_HUMAN (P15735) Phosphorylase b kinase gamma catalytic chain, testis/liver| isoform (EC 2.7.11.19) (PHK-gamma-T) (Phosphorylase kinase gamma subunit 2) (PSK-C3) Length = 406 Score = 37.4 bits (85), Expect(2) = 1e-04 Identities = 26/73 (35%), Positives = 42/73 (57%), Gaps = 7/73 (9%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEF--CNGEITY-----QLDI 503 LLD N+ +++DFG S C E + + GT GYLAPE C+ + T+ ++D+ Sbjct: 160 LLDDNMQIRLSDFGFS-CHLEPGEK--LRELCGTPGYLAPEILKCSMDETHPGYGKEVDL 216 Query: 502 YSVGVIIIEILTG 464 ++ GVI+ +L G Sbjct: 217 WACGVILFTLLAG 229 Score = 27.7 bits (60), Expect(2) = 1e-04 Identities = 11/18 (61%), Positives = 13/18 (72%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 LH NI+H DLKP NI + Sbjct: 144 LHANNIVHRDLKPENILL 161
>PKNL_MYCTU (O53510) Probable serine/threonine-protein kinase pknL (EC| 2.7.11.1) Length = 399 Score = 42.0 bits (97), Expect(2) = 1e-04 Identities = 27/65 (41%), Positives = 39/65 (60%), Gaps = 1/65 (1%) Frame = -3 Query: 655 DGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFC-NGEITYQLDIYSVGVIII 479 DG++ K+ADFG+ R + V I GT YL+PE +G + D+YSVGV++ Sbjct: 153 DGDV--KLADFGLVRAVAAASITSTGV-ILGTAAYLSPEQVRDGNADPRSDVYSVGVLVY 209 Query: 478 EILTG 464 E+LTG Sbjct: 210 ELLTG 214 Score = 23.1 bits (48), Expect(2) = 1e-04 Identities = 7/17 (41%), Positives = 12/17 (70%) Frame = -2 Query: 707 HQRNILHLDLKPANIFV 657 H+ ++H D+KP NI + Sbjct: 134 HRAGLVHRDVKPENILI 150
>PKNL_MYCBO (Q7TYY6) Probable serine/threonine-protein kinase pknL (EC| 2.7.11.1) Length = 399 Score = 42.0 bits (97), Expect(2) = 1e-04 Identities = 27/65 (41%), Positives = 39/65 (60%), Gaps = 1/65 (1%) Frame = -3 Query: 655 DGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFC-NGEITYQLDIYSVGVIII 479 DG++ K+ADFG+ R + V I GT YL+PE +G + D+YSVGV++ Sbjct: 153 DGDV--KLADFGLVRAVAAASITSTGV-ILGTAAYLSPEQVRDGNADPRSDVYSVGVLVY 209 Query: 478 EILTG 464 E+LTG Sbjct: 210 ELLTG 214 Score = 23.1 bits (48), Expect(2) = 1e-04 Identities = 7/17 (41%), Positives = 12/17 (70%) Frame = -2 Query: 707 HQRNILHLDLKPANIFV 657 H+ ++H D+KP NI + Sbjct: 134 HRAGLVHRDVKPENILI 150
>CDC2_CAEEL (P34556) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) Length = 332 Score = 36.6 bits (83), Expect(2) = 1e-04 Identities = 26/69 (37%), Positives = 37/69 (53%), Gaps = 2/69 (2%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEITYQL--DIYSVGV 488 L+D N K+ADFG++R + R T + TL Y APE G Y + D++S+G Sbjct: 153 LVDNNGAIKLADFGLARAI-GIPIRVYTHEV-VTLWYRAPEILMGAQRYSMGVDMWSIGC 210 Query: 487 IIIEILTGK 461 I E+ T K Sbjct: 211 IFAEMATKK 219 Score = 28.5 bits (62), Expect(2) = 1e-04 Identities = 10/17 (58%), Positives = 13/17 (76%) Frame = -2 Query: 707 HQRNILHLDLKPANIFV 657 HQR ++H DLKP N+ V Sbjct: 138 HQRRVIHRDLKPQNLLV 154
>PHO85_YEAST (P17157) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 305 Score = 38.9 bits (89), Expect(2) = 1e-04 Identities = 26/65 (40%), Positives = 35/65 (53%), Gaps = 6/65 (9%) Frame = -3 Query: 637 KIADFGVSRCFHEMQSRAITVNIRG----TLGYLAPEFCNGEITYQ--LDIYSVGVIIIE 476 K+ DFG++R F I VN TL Y AP+ G TY +DI+S G I+ E Sbjct: 148 KLGDFGLARAF------GIPVNTFSSEVVTLWYRAPDVLMGSRTYSTSIDIWSCGCILAE 201 Query: 475 ILTGK 461 ++TGK Sbjct: 202 MITGK 206 Score = 26.2 bits (56), Expect(2) = 1e-04 Identities = 9/17 (52%), Positives = 12/17 (70%) Frame = -2 Query: 707 HQRNILHLDLKPANIFV 657 H+ ILH DLKP N+ + Sbjct: 125 HENKILHRDLKPQNLLI 141
>CDC2_CARAU (P51958) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 302 Score = 39.3 bits (90), Expect(2) = 1e-04 Identities = 27/69 (39%), Positives = 38/69 (55%), Gaps = 2/69 (2%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEITYQ--LDIYSVGV 488 L+D V K+ADFG++R F + R T + TL Y APE G Y +D++S+G Sbjct: 135 LIDNKGVIKLADFGLARAF-GVPVRVYTHEV-VTLWYRAPEVLLGASRYSTPVDVWSIGT 192 Query: 487 IIIEILTGK 461 I E+ T K Sbjct: 193 IFAELATKK 201 Score = 25.8 bits (55), Expect(2) = 1e-04 Identities = 9/17 (52%), Positives = 12/17 (70%) Frame = -2 Query: 707 HQRNILHLDLKPANIFV 657 H R +LH DLKP N+ + Sbjct: 120 HCRRVLHRDLKPQNLLI 136
>PHO85_CANGA (Q6FKD4) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 302 Score = 38.9 bits (89), Expect(2) = 1e-04 Identities = 26/65 (40%), Positives = 35/65 (53%), Gaps = 6/65 (9%) Frame = -3 Query: 637 KIADFGVSRCFHEMQSRAITVNIRG----TLGYLAPEFCNGEITYQ--LDIYSVGVIIIE 476 K+ DFG++R F I VN TL Y AP+ G TY +DI+S G I+ E Sbjct: 147 KLGDFGLARAF------GIPVNTFSSEVVTLWYRAPDVLMGSRTYSTSIDIWSCGCILAE 200 Query: 475 ILTGK 461 ++TGK Sbjct: 201 MITGK 205 Score = 26.2 bits (56), Expect(2) = 1e-04 Identities = 9/17 (52%), Positives = 12/17 (70%) Frame = -2 Query: 707 HQRNILHLDLKPANIFV 657 H+ ILH DLKP N+ + Sbjct: 124 HENKILHRDLKPQNLLI 140
>BRAF1_COTJA (P34908) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (RMIL serine/threonine-protein kinase) (c-RMIL) Length = 807 Score = 38.9 bits (89), Expect(2) = 2e-04 Identities = 20/78 (25%), Positives = 41/78 (52%), Gaps = 4/78 (5%) Frame = -3 Query: 658 LDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGE----ITYQLDIYSVG 491 L +L KI DFG++ + G++ ++APE + ++Q D+Y+ G Sbjct: 624 LHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFG 683 Query: 490 VIIIEILTGKKGYLAVDN 437 +++ E++TG+ Y ++N Sbjct: 684 IVLYELMTGQLPYSNINN 701 Score = 25.8 bits (55), Expect(2) = 2e-04 Identities = 10/18 (55%), Positives = 14/18 (77%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 LH ++I+H DLK NIF+ Sbjct: 607 LHAKSIIHRDLKSNNIFL 624
>BRAF1_CHICK (Q04982) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Rmil serine/threonine-protein kinase) (c-Rmil) Length = 806 Score = 38.9 bits (89), Expect(2) = 2e-04 Identities = 20/78 (25%), Positives = 41/78 (52%), Gaps = 4/78 (5%) Frame = -3 Query: 658 LDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGE----ITYQLDIYSVG 491 L +L KI DFG++ + G++ ++APE + ++Q D+Y+ G Sbjct: 624 LHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFG 683 Query: 490 VIIIEILTGKKGYLAVDN 437 +++ E++TG+ Y ++N Sbjct: 684 IVLYELMTGQLPYSNINN 701 Score = 25.8 bits (55), Expect(2) = 2e-04 Identities = 10/18 (55%), Positives = 14/18 (77%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 LH ++I+H DLK NIF+ Sbjct: 607 LHAKSIIHRDLKSNNIFL 624
>BRAF1_HUMAN (P15056) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (p94) (v-Raf murine sarcoma viral oncogene homolog B1) Length = 766 Score = 38.9 bits (89), Expect(2) = 2e-04 Identities = 20/78 (25%), Positives = 41/78 (52%), Gaps = 4/78 (5%) Frame = -3 Query: 658 LDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGE----ITYQLDIYSVG 491 L +L KI DFG++ + G++ ++APE + ++Q D+Y+ G Sbjct: 584 LHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFG 643 Query: 490 VIIIEILTGKKGYLAVDN 437 +++ E++TG+ Y ++N Sbjct: 644 IVLYELMTGQLPYSNINN 661 Score = 25.8 bits (55), Expect(2) = 2e-04 Identities = 10/18 (55%), Positives = 14/18 (77%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 LH ++I+H DLK NIF+ Sbjct: 567 LHAKSIIHRDLKSNNIFL 584
>IKKA_MOUSE (Q60680) Inhibitor of nuclear factor kappa-B kinase alpha subunit| (EC 2.7.11.10) (I kappa-B kinase alpha) (IkBKA) (IKK-alpha) (IKK-A) (IkappaB kinase) (I-kappa-B kinase 1) (IKK1) (Conserved helix-loop-helix ubiquitous kinase) (Nuclear factor N Length = 745 Score = 38.1 bits (87), Expect(2) = 2e-04 Identities = 22/69 (31%), Positives = 37/69 (53%), Gaps = 1/69 (1%) Frame = -3 Query: 652 GNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPE-FCNGEITYQLDIYSVGVIIIE 476 G + KI D G ++ ++ ++ + GTL YLAPE F N T +D +S G ++ E Sbjct: 157 GKTIHKIIDLGYAK---DVDQGSLCTSFVGTLQYLAPELFENKPYTATVDYWSFGTMVFE 213 Query: 475 ILTGKKGYL 449 + G + +L Sbjct: 214 CIAGYRPFL 222 Score = 26.6 bits (57), Expect(2) = 2e-04 Identities = 10/16 (62%), Positives = 12/16 (75%) Frame = -2 Query: 710 LHQRNILHLDLKPANI 663 LH+ I+H DLKP NI Sbjct: 135 LHENKIIHRDLKPENI 150
>STE11_YEAST (P23561) Serine/threonine-protein kinase STE11 (EC 2.7.11.1)| Length = 738 Score = 36.6 bits (83), Expect(2) = 2e-04 Identities = 21/69 (30%), Positives = 39/69 (56%), Gaps = 2/69 (2%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAIT-VNIRGTLGYLAPEFCNGEITY-QLDIYSVGV 488 L+D KI DFG+S+ + + +++G++ +++PE T + DI+S G Sbjct: 607 LIDIKGCVKITDFGISKKLSPLNKKQNKRASLQGSVFWMSPEVVKQTATTAKADIWSTGC 666 Query: 487 IIIEILTGK 461 ++IE+ TGK Sbjct: 667 VVIEMFTGK 675 Score = 28.1 bits (61), Expect(2) = 2e-04 Identities = 10/18 (55%), Positives = 15/18 (83%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 LH++NI+H D+K ANI + Sbjct: 591 LHKKNIIHRDIKGANILI 608
>RAF1_MOUSE (Q99N57) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Raf-1) (C-RAF) (cRaf) Length = 648 Score = 37.7 bits (86), Expect(2) = 2e-04 Identities = 20/78 (25%), Positives = 38/78 (48%), Gaps = 4/78 (5%) Frame = -3 Query: 658 LDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFC----NGEITYQLDIYSVG 491 L L KI DFG++ G++ ++APE + ++Q D+YS G Sbjct: 476 LHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDDNPFSFQSDVYSYG 535 Query: 490 VIIIEILTGKKGYLAVDN 437 +++ E++ G+ Y ++N Sbjct: 536 IVLYELMAGELPYAHINN 553 Score = 26.9 bits (58), Expect(2) = 2e-04 Identities = 10/18 (55%), Positives = 14/18 (77%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 LH +NI+H D+K NIF+ Sbjct: 459 LHAKNIIHRDMKSNNIFL 476
>SNF1_SCHPO (O74536) SNF1-like protein kinase ssp2 (EC 2.7.11.1)| Length = 576 Score = 40.8 bits (94), Expect(2) = 2e-04 Identities = 25/69 (36%), Positives = 38/69 (55%), Gaps = 2/69 (2%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEITY--QLDIYSVGV 488 LLD NL KIADFG+S M G+ Y APE NG++ ++D++S G+ Sbjct: 163 LLDDNLNVKIADFGLSNI---MTDGNFLKTSCGSPNYAAPEVINGKLYAGPEVDVWSCGI 219 Query: 487 IIIEILTGK 461 ++ +L G+ Sbjct: 220 VLYVMLVGR 228 Score = 23.9 bits (50), Expect(2) = 2e-04 Identities = 8/17 (47%), Positives = 12/17 (70%) Frame = -2 Query: 707 HQRNILHLDLKPANIFV 657 H+ I+H DLKP N+ + Sbjct: 148 HRHKIVHRDLKPENLLL 164
>PMYT1_XENLA (Q91618) Membrane-associated tyrosine- and threonine-specific| cdc2-inhibitory kinase (EC 2.7.11.1) (Myt1 kinase) Length = 548 Score = 37.0 bits (84), Expect(2) = 2e-04 Identities = 13/20 (65%), Positives = 18/20 (90%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFVGW 651 LH RN+LHLD+KPAN+F+ + Sbjct: 217 LHDRNLLHLDIKPANVFISF 236 Score = 27.7 bits (60), Expect(2) = 2e-04 Identities = 18/67 (26%), Positives = 31/67 (46%), Gaps = 10/67 (14%) Frame = -3 Query: 643 VPKIADFGVSRCFHEMQSRAITVNIRGTLG----------YLAPEFCNGEITYQLDIYSV 494 V K+ DFG + V + GT G Y+APE +G + D++S+ Sbjct: 239 VCKLGDFG------------LMVELDGTEGSGEAQEGDPRYMAPELLDGIFSKAADVFSL 286 Query: 493 GVIIIEI 473 G+ ++E+ Sbjct: 287 GMSLLEV 293
>UME5_YEAST (P39073) Meiotic mRNA stability protein kinase UME5 (EC 2.7.11.23)| Length = 541 Score = 34.7 bits (78), Expect(2) = 2e-04 Identities = 22/59 (37%), Positives = 32/59 (54%), Gaps = 3/59 (5%) Frame = -3 Query: 637 KIADFGVSRCFHEMQSRAITVN-IRGTLGYLAPEFCNG--EITYQLDIYSVGVIIIEIL 470 KI D G++R FH M T + + T+ Y APE G T +D++SVG I E++ Sbjct: 287 KIGDLGLARKFHNMLQTLYTGDKVVVTIWYRAPELLLGARHYTPAVDLWSVGCIFAELI 345 Score = 30.0 bits (66), Expect(2) = 2e-04 Identities = 13/18 (72%), Positives = 14/18 (77%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 LHQ +LH DLKPANI V Sbjct: 263 LHQNWVLHRDLKPANIMV 280
>RKIN1_SECCE (Q02723) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 502 Score = 41.2 bits (95), Expect(2) = 2e-04 Identities = 24/68 (35%), Positives = 38/68 (55%), Gaps = 2/68 (2%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEITY--QLDIYSVGV 488 LLD K+ADFG+S H+ + G+L Y APE +G++ ++D++S GV Sbjct: 147 LLDSKYNVKLADFGLSNVMHDGHFLKTSC---GSLNYAAPEVISGKLYAGPEIDVWSCGV 203 Query: 487 IIIEILTG 464 I+ +L G Sbjct: 204 ILYALLCG 211 Score = 23.5 bits (49), Expect(2) = 2e-04 Identities = 7/17 (41%), Positives = 12/17 (70%) Frame = -2 Query: 707 HQRNILHLDLKPANIFV 657 H+ ++H DLKP N+ + Sbjct: 132 HRNKVVHRDLKPENLLL 148
>RMIL_AVEVR (P27966) Serine/threonine-protein kinase transforming protein Rmil| (EC 2.7.11.1) Length = 450 Score = 38.9 bits (89), Expect(2) = 2e-04 Identities = 20/78 (25%), Positives = 41/78 (52%), Gaps = 4/78 (5%) Frame = -3 Query: 658 LDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGE----ITYQLDIYSVG 491 L +L KI DFG++ + G++ ++APE + ++Q D+Y+ G Sbjct: 210 LHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFG 269 Query: 490 VIIIEILTGKKGYLAVDN 437 +++ E++TG+ Y ++N Sbjct: 270 IVLYELMTGQLPYSNINN 287 Score = 25.8 bits (55), Expect(2) = 2e-04 Identities = 10/18 (55%), Positives = 14/18 (77%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 LH ++I+H DLK NIF+ Sbjct: 193 LHAKSIIHRDLKSNNIFL 210
>STK11_XENLA (Q91604) Serine/threonine-protein kinase 11 (EC 2.7.11.1)| (Serine/threonine-protein kinase XEEK1) (Egg and embryo kinase 1) Length = 432 Score = 39.7 bits (91), Expect(2) = 2e-04 Identities = 31/115 (26%), Positives = 55/115 (47%), Gaps = 3/115 (2%) Frame = -3 Query: 655 DGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEIT---YQLDIYSVGVI 485 DG L KI+D GV+ H +G+ + PE NG T +++DI+S GV Sbjct: 190 DGTL--KISDLGVAEALHPFAEGDTCRTSQGSPAFQPPEIANGLDTFSGFKVDIWSAGVT 247 Query: 484 IIEILTGKKGYLAVDNVVESWSNKLEKSQSDVQLKQVRICAEIGIECTDFNPAKR 320 + I TG + DN+ + + N + K + + + +++ +++PAKR Sbjct: 248 LYNITTGLYPFEG-DNIYKLFEN-IGKGDYSIPEECGPLLSDLLRGMLEYDPAKR 300 Score = 25.0 bits (53), Expect(2) = 2e-04 Identities = 8/18 (44%), Positives = 13/18 (72%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 LH + I+H D+KP N+ + Sbjct: 170 LHSQGIVHKDIKPGNLLL 187
>PHKG2_RAT (P31325) Phosphorylase b kinase gamma catalytic chain, testis/liver| isoform (EC 2.7.11.19) (PHK-gamma-T) (Phosphorylase kinase gamma subunit 2) Length = 406 Score = 37.4 bits (85), Expect(2) = 2e-04 Identities = 26/73 (35%), Positives = 42/73 (57%), Gaps = 7/73 (9%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEF--CNGEITY-----QLDI 503 LLD N+ +++DFG S C E + + GT GYLAPE C+ + T+ ++D+ Sbjct: 160 LLDDNMQIRLSDFGFS-CHLEPGEK--LRELCGTPGYLAPEILKCSMDETHPGYGKEVDL 216 Query: 502 YSVGVIIIEILTG 464 ++ GVI+ +L G Sbjct: 217 WACGVILFTLLAG 229 Score = 27.3 bits (59), Expect(2) = 2e-04 Identities = 11/18 (61%), Positives = 13/18 (72%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 LH NI+H DLKP NI + Sbjct: 144 LHVNNIVHRDLKPENILL 161
>RMIL_AVII1 (P10533) Serine/threonine-protein kinase transforming protein Rmil| (EC 2.7.11.1) Length = 367 Score = 38.9 bits (89), Expect(2) = 2e-04 Identities = 20/78 (25%), Positives = 41/78 (52%), Gaps = 4/78 (5%) Frame = -3 Query: 658 LDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGE----ITYQLDIYSVG 491 L +L KI DFG++ + G++ ++APE + ++Q D+Y+ G Sbjct: 194 LHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFG 253 Query: 490 VIIIEILTGKKGYLAVDN 437 +++ E++TG+ Y ++N Sbjct: 254 IVLYELMTGQLPYSNINN 271 Score = 25.8 bits (55), Expect(2) = 2e-04 Identities = 10/18 (55%), Positives = 14/18 (77%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 LH ++I+H DLK NIF+ Sbjct: 177 LHAKSIIHRDLKSNNIFL 194
>MAPK_FUSSO (Q00859) Mitogen-activated protein kinase (EC 2.7.11.24) (FsMAPK)| Length = 355 Score = 37.0 bits (84), Expect(2) = 2e-04 Identities = 24/70 (34%), Positives = 36/70 (51%), Gaps = 3/70 (4%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRA-ITVNIRGTLGYLAPEFCNG--EITYQLDIYSVG 491 LL+ N K+ DFG++R + + T Y APE E T +D++SVG Sbjct: 154 LLNANCDLKVCDFGLARSAASQEDNSGFMTEYVATRWYRAPEIMLTFKEYTKAIDVWSVG 213 Query: 490 VIIIEILTGK 461 I+ E+L+GK Sbjct: 214 CILAEMLSGK 223 Score = 27.7 bits (60), Expect(2) = 2e-04 Identities = 9/18 (50%), Positives = 14/18 (77%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 +H N+LH DLKP+N+ + Sbjct: 138 MHSANVLHRDLKPSNLLL 155
>BRAF1_MOUSE (P28028) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Fragment) Length = 328 Score = 38.9 bits (89), Expect(2) = 2e-04 Identities = 20/78 (25%), Positives = 41/78 (52%), Gaps = 4/78 (5%) Frame = -3 Query: 658 LDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGE----ITYQLDIYSVG 491 L +L KI DFG++ + G++ ++APE + ++Q D+Y+ G Sbjct: 146 LHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFG 205 Query: 490 VIIIEILTGKKGYLAVDN 437 +++ E++TG+ Y ++N Sbjct: 206 IVLYELMTGQLPYSNINN 223 Score = 25.8 bits (55), Expect(2) = 2e-04 Identities = 10/18 (55%), Positives = 14/18 (77%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 LH ++I+H DLK NIF+ Sbjct: 129 LHAKSIIHRDLKSNNIFL 146
>RAF_MSV36 (P00532) Serine/threonine-protein kinase transforming protein raf| (EC 2.7.11.1) Length = 323 Score = 37.7 bits (86), Expect(2) = 2e-04 Identities = 20/78 (25%), Positives = 38/78 (48%), Gaps = 4/78 (5%) Frame = -3 Query: 658 LDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFC----NGEITYQLDIYSVG 491 L L KI DFG++ G++ ++APE + ++Q D+YS G Sbjct: 151 LHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDDNPFSFQSDVYSYG 210 Query: 490 VIIIEILTGKKGYLAVDN 437 +++ E++ G+ Y ++N Sbjct: 211 IVLYELMAGELPYAHINN 228 Score = 26.9 bits (58), Expect(2) = 2e-04 Identities = 10/18 (55%), Positives = 14/18 (77%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 LH +NI+H D+K NIF+ Sbjct: 134 LHAKNIIHRDMKSNNIFL 151
>AURKB_PIG (Q9N0X0) Serine/threonine-protein kinase 12 (EC 2.7.11.1)| (Aurora-B) (Fragment) Length = 156 Score = 38.5 bits (88), Expect(2) = 2e-04 Identities = 28/66 (42%), Positives = 36/66 (54%), Gaps = 1/66 (1%) Frame = -3 Query: 658 LDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEI-TYQLDIYSVGVII 482 L G L KIADFG S H R T+ RGTL YL PE G ++D++ +GV+ Sbjct: 61 LQGEL--KIADFGWS--VHAPSLRRKTM--RGTLDYLPPEMIEGRTHNEKVDLWCIGVLC 114 Query: 481 IEILTG 464 E+L G Sbjct: 115 YELLVG 120 Score = 26.2 bits (56), Expect(2) = 2e-04 Identities = 8/20 (40%), Positives = 14/20 (70%) Frame = -2 Query: 707 HQRNILHLDLKPANIFVGWQ 648 H + ++H D+KP N+ +G Q Sbjct: 43 HGKKVIHRDIKPENLLLGLQ 62
>SPEG_BRARE (Q696W0) Striated muscle preferentially expressed protein kinase (EC| 2.7.11.1) Length = 2995 Score = 36.2 bits (82), Expect(2) = 2e-04 Identities = 22/62 (35%), Positives = 38/62 (61%), Gaps = 1/62 (1%) Frame = -3 Query: 643 VPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEIT-YQLDIYSVGVIIIEILT 467 V KI DFG ++ F+ + + + + GTL Y+APE G++ DI+S+GV+ +L+ Sbjct: 2814 VIKIIDFGSAQRFNPLSLQQCSRYL-GTLEYMAPEMLKGDLVGPPADIWSLGVLSYIMLS 2872 Query: 466 GK 461 G+ Sbjct: 2873 GR 2874 Score = 31.2 bits (69), Expect = 3.3 Identities = 13/21 (61%), Positives = 16/21 (76%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFVGWQ 648 LHQ +I+HLDLKP NI + Q Sbjct: 1363 LHQNDIIHLDLKPENILMADQ 1383 Score = 28.1 bits (61), Expect(2) = 2e-04 Identities = 12/18 (66%), Positives = 13/18 (72%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 LH ILHLD+KP NI V Sbjct: 2792 LHNCKILHLDIKPDNIMV 2809
>CD2L7_HUMAN (Q9NYV4) Cell division cycle 2-related protein kinase 7 (EC| 2.7.11.22) (CDC2-related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS) Length = 1490 Score = 40.8 bits (94), Expect(2) = 2e-04 Identities = 26/69 (37%), Positives = 40/69 (57%), Gaps = 2/69 (2%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEITY--QLDIYSVGV 488 LL+ + K+ADFG++R ++ +SR T + TL Y PE GE Y +D++S G Sbjct: 866 LLNNSGQIKLADFGLARLYNSEESRPYTNKVI-TLWYRPPELLLGEERYTPAIDVWSCGC 924 Query: 487 IIIEILTGK 461 I+ E+ T K Sbjct: 925 ILGELFTKK 933 Score = 23.5 bits (49), Expect(2) = 2e-04 Identities = 8/17 (47%), Positives = 13/17 (76%) Frame = -2 Query: 707 HQRNILHLDLKPANIFV 657 H++N LH D+K +NI + Sbjct: 851 HKKNFLHRDIKCSNILL 867
>ZYG1_CAEEL (Q9GT24) Probable serine/threonine-protein kinase zyg-1 (EC| 2.7.11.1) (Zygote defective protein 1) Length = 706 Score = 39.7 bits (91), Expect(2) = 2e-04 Identities = 19/59 (32%), Positives = 34/59 (57%) Frame = -3 Query: 637 KIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEITYQLDIYSVGVIIIEILTGK 461 K+ DFG++ ++ T I GT G++AP+ + E T D+YS+G ++ +LT + Sbjct: 150 KLGDFGLATTLGRGET---TCTIVGTPGFIAPQVYDQEYTQSADVYSLGAVLYTMLTAR 205 Score = 24.6 bits (52), Expect(2) = 2e-04 Identities = 7/18 (38%), Positives = 13/18 (72%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 +H+ N++H DL N+F+ Sbjct: 122 MHRVNVIHRDLSAGNVFI 139
>SCK1_SCHPO (P50530) Serine/threonine-protein kinase sck1 (EC 2.7.11.1)| Length = 696 Score = 39.7 bits (91), Expect(2) = 2e-04 Identities = 26/76 (34%), Positives = 40/76 (52%), Gaps = 2/76 (2%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEITY--QLDIYSVGV 488 LLD + + DFG+S+ + + A T GT YLAPE + Y Q+D +S+GV Sbjct: 435 LLDADGHIALCDFGLSKA--NLSANATTNTFCGTTEYLAPEVLLEDKGYTKQVDFWSLGV 492 Query: 487 IIIEILTGKKGYLAVD 440 ++ E+ G + A D Sbjct: 493 LVFEMCCGWSPFYAPD 508 Score = 24.6 bits (52), Expect(2) = 2e-04 Identities = 9/18 (50%), Positives = 14/18 (77%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 LH+ +I++ DLKP NI + Sbjct: 419 LHKHDIIYRDLKPENILL 436
>PKN1_MYXXA (P33973) Serine/threonine-protein kinase pkn1 (EC 2.7.11.1)| Length = 693 Score = 36.6 bits (83), Expect(2) = 2e-04 Identities = 20/60 (33%), Positives = 34/60 (56%), Gaps = 1/60 (1%) Frame = -3 Query: 637 KIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGE-ITYQLDIYSVGVIIIEILTGK 461 K+ DFG+++ + I GT Y+APE G + + D+Y++GVI ++LTG+ Sbjct: 199 KVLDFGIAKLADAHMPQTHAGIIVGTPEYMAPEQSLGRGVDGRADLYALGVIAYQLLTGR 258 Score = 27.7 bits (60), Expect(2) = 2e-04 Identities = 11/17 (64%), Positives = 13/17 (76%) Frame = -2 Query: 707 HQRNILHLDLKPANIFV 657 H R I+H DLKP NIF+ Sbjct: 172 HARGIVHRDLKPDNIFL 188
>PMYT1_CAEEL (O18209) Membrane-associated tyrosine- and threonine-specific| cdc2-inhibitory kinase (EC 2.7.11.1) (Myt1 kinase) (Lethal protein 37) Length = 677 Score = 38.1 bits (87), Expect(2) = 2e-04 Identities = 37/148 (25%), Positives = 62/148 (41%), Gaps = 7/148 (4%) Frame = -3 Query: 658 LDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEITYQLDIYSVGVIII 479 L +++ K+ DFG+ + + G YLAPE NG T DI+S+G+ I+ Sbjct: 236 LTKDMICKLGDFGL--VINLKNPNDVKSAEEGDSKYLAPEVLNGRPTKSSDIFSLGMTIL 293 Query: 478 EILTGKKGYLAVDNVVESWSNKLEKSQSDVQLKQVRICAEIGIE-------CTDFNPAKR 320 E T L V + +SW D R A I + D +P R Sbjct: 294 EATTD----LDVPSNGDSWHQIRNGQIPD------RFFAGISTDLRSLIALMLDSDPRIR 343 Query: 319 PGTKNIIDRLVSLDETDSMGGYIETSAV 236 P +++++D V + G Y++ ++ Sbjct: 344 PTSRDLLDHPVIKKKLMKRGTYVKCISI 371 Score = 26.2 bits (56), Expect(2) = 2e-04 Identities = 9/18 (50%), Positives = 14/18 (77%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 LH +++H D+KP NIF+ Sbjct: 219 LHSNDMIHDDIKPENIFL 236
>FGFR2_HUMAN (P21802) Fibroblast growth factor receptor 2 precursor (EC 2.7.10.1)| (FGFR-2) (Keratinocyte growth factor receptor 2) (CD332 antigen) Length = 821 Score = 45.1 bits (105), Expect = 2e-04 Identities = 43/153 (28%), Positives = 72/153 (47%), Gaps = 5/153 (3%) Frame = -3 Query: 670 RTYLLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEI-TYQLDIYSV 494 R L+ N V KIADFG++R + + T N R + ++APE + T+Q D++S Sbjct: 630 RNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSF 689 Query: 493 GVIIIEILT-GKKGYLAVDNVVESWSNKLEKSQSDVQLKQVRICAEIGIECTDFNPAKRP 317 GV++ EI T G Y + V E + E + D + +C P++RP Sbjct: 690 GVLMWEIFTLGGSPYPGIP-VEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRP 748 Query: 316 GTKNII---DRLVSLDETDSMGGYIETSAVTSQ 227 K ++ DR+++L + Y++ S Q Sbjct: 749 TFKQLVEDLDRILTLTTNEE---YLDLSQPLEQ 778
>FGFR2_XENLA (Q03364) Fibroblast growth factor receptor 2 precursor (EC 2.7.10.1)| (FGFR-2) Length = 813 Score = 45.1 bits (105), Expect = 2e-04 Identities = 44/153 (28%), Positives = 72/153 (47%), Gaps = 5/153 (3%) Frame = -3 Query: 670 RTYLLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEI-TYQLDIYSV 494 R L+ N V KIADFG++R + + T N R + ++APE + T+Q D++S Sbjct: 620 RNVLVTENNVMKIADFGLARDVNNIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSF 679 Query: 493 GVIIIEILT-GKKGYLAVDNVVESWSNKLEKSQSDVQLKQVRICAEIGIECTDFNPAKRP 317 GV++ EI T G Y + V E + E + D + +C P+ RP Sbjct: 680 GVLMWEIFTLGGSPYPGIP-VEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAIPSHRP 738 Query: 316 GTKNII---DRLVSLDETDSMGGYIETSAVTSQ 227 K ++ DR+++L + Y++ SA Q Sbjct: 739 TFKQLVEDLDRILTLTTNEE---YLDLSAPLEQ 768
>KPC3_CAEEL (Q19266) Protein kinase C-like 3 (EC 2.7.11.13) (Atypical protein| kinase C-3) (aPKC3) Length = 597 Score = 42.4 bits (98), Expect(2) = 2e-04 Identities = 36/151 (23%), Positives = 71/151 (47%), Gaps = 9/151 (5%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNG-EITYQLDIYSVGVI 485 L+D K+ D+G+ C ++ +T GT Y+APE G E + +D +++GV+ Sbjct: 384 LIDAEGHIKLTDYGM--CKENIKDGDLTSTFCGTPNYIAPEILRGDEYGFSVDWWALGVL 441 Query: 484 IIEILTGKKGYLAVDNVVESWSNKLEKSQSDVQLKQVRICAEIGIECTDF-------NPA 326 + E++ G+ + V + S N + + +Q+RI + + + +P Sbjct: 442 MFEMMAGRSPFDIV-GMQNSEENTEDYLFQIILERQIRIPRSLSVRASGILKGFLNKDPT 500 Query: 325 KRPGTK-NIIDRLVSLDETDSMGGYIETSAV 236 +R G K +I + L + E G+I+ A+ Sbjct: 501 ERLGCKLDINEGLRDMKEHQFFRGFIDWEAL 531 Score = 21.9 bits (45), Expect(2) = 2e-04 Identities = 8/18 (44%), Positives = 12/18 (66%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 LH R I++ DLK N+ + Sbjct: 368 LHSRGIIYRDLKLDNVLI 385
>AAPK1_CAEEL (P45894) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMP-activated kinase 1) Length = 589 Score = 41.6 bits (96), Expect(2) = 2e-04 Identities = 34/124 (27%), Positives = 58/124 (46%), Gaps = 2/124 (1%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEITY--QLDIYSVGV 488 LLD N KIADFG+S + M + G+ Y APE + ++ ++D++S GV Sbjct: 154 LLDANKNIKIADFGLS---NYMTDGDLLSTACGSPNYAAPELISNKLYVGPEVDLWSCGV 210 Query: 487 IIIEILTGKKGYLAVDNVVESWSNKLEKSQSDVQLKQVRICAEIGIECTDFNPAKRPGTK 308 I+ +L G + D V + K++ + V + A++ +P KR K Sbjct: 211 ILYAMLCGTLPF--DDQNVPTLFAKIKSGRYTVPYSMEKQAADLISTMLQVDPVKRADVK 268 Query: 307 NIID 296 I++ Sbjct: 269 RIVN 272 Score = 22.7 bits (47), Expect(2) = 2e-04 Identities = 8/17 (47%), Positives = 11/17 (64%) Frame = -2 Query: 707 HQRNILHLDLKPANIFV 657 H I+H DLKP N+ + Sbjct: 139 HNHMIVHRDLKPENLLL 155
>CDC2_RAT (P39951) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 37.4 bits (85), Expect(2) = 2e-04 Identities = 26/69 (37%), Positives = 37/69 (53%), Gaps = 2/69 (2%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEITYQ--LDIYSVGV 488 L+D K+ADFG++R F + R T + TL Y +PE G Y +DI+S+G Sbjct: 135 LIDDKGTIKLADFGLARAF-GIPIRVYTHEV-VTLWYRSPEVLLGSARYSTPVDIWSIGT 192 Query: 487 IIIEILTGK 461 I E+ T K Sbjct: 193 IFAELATKK 201 Score = 26.9 bits (58), Expect(2) = 2e-04 Identities = 9/17 (52%), Positives = 12/17 (70%) Frame = -2 Query: 707 HQRNILHLDLKPANIFV 657 H R +LH DLKP N+ + Sbjct: 120 HSRRVLHRDLKPQNLLI 136
>CDC2_PONPY (Q5RCH1) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 37.4 bits (85), Expect(2) = 2e-04 Identities = 26/69 (37%), Positives = 37/69 (53%), Gaps = 2/69 (2%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEITYQ--LDIYSVGV 488 L+D K+ADFG++R F + R T + TL Y +PE G Y +DI+S+G Sbjct: 135 LIDDKGTIKLADFGLARAF-GIPIRVYTHEV-VTLWYRSPEVLLGSARYSTPVDIWSIGT 192 Query: 487 IIIEILTGK 461 I E+ T K Sbjct: 193 IFAELATKK 201 Score = 26.9 bits (58), Expect(2) = 2e-04 Identities = 9/17 (52%), Positives = 12/17 (70%) Frame = -2 Query: 707 HQRNILHLDLKPANIFV 657 H R +LH DLKP N+ + Sbjct: 120 HSRRVLHRDLKPQNLLI 136
>CDC2_MOUSE (P11440) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 37.4 bits (85), Expect(2) = 2e-04 Identities = 26/69 (37%), Positives = 37/69 (53%), Gaps = 2/69 (2%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEITYQ--LDIYSVGV 488 L+D K+ADFG++R F + R T + TL Y +PE G Y +DI+S+G Sbjct: 135 LIDDKGTIKLADFGLARAF-GIPIRVYTHEV-VTLWYRSPEVLLGSARYSTPVDIWSIGT 192 Query: 487 IIIEILTGK 461 I E+ T K Sbjct: 193 IFAELATKK 201 Score = 26.9 bits (58), Expect(2) = 2e-04 Identities = 9/17 (52%), Positives = 12/17 (70%) Frame = -2 Query: 707 HQRNILHLDLKPANIFV 657 H R +LH DLKP N+ + Sbjct: 120 HSRRVLHRDLKPQNLLI 136
>CDC2_HUMAN (P06493) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 37.4 bits (85), Expect(2) = 2e-04 Identities = 26/69 (37%), Positives = 37/69 (53%), Gaps = 2/69 (2%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEITYQ--LDIYSVGV 488 L+D K+ADFG++R F + R T + TL Y +PE G Y +DI+S+G Sbjct: 135 LIDDKGTIKLADFGLARAF-GIPIRVYTHEV-VTLWYRSPEVLLGSARYSTPVDIWSIGT 192 Query: 487 IIIEILTGK 461 I E+ T K Sbjct: 193 IFAELATKK 201 Score = 26.9 bits (58), Expect(2) = 2e-04 Identities = 9/17 (52%), Positives = 12/17 (70%) Frame = -2 Query: 707 HQRNILHLDLKPANIFV 657 H R +LH DLKP N+ + Sbjct: 120 HSRRVLHRDLKPQNLLI 136
>CDC2_DROME (P23572) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) Length = 297 Score = 37.0 bits (84), Expect(2) = 2e-04 Identities = 28/69 (40%), Positives = 38/69 (55%), Gaps = 2/69 (2%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEITYQ--LDIYSVGV 488 L+D + + K+ADFG+ R F + R T I TL Y APE G Y +DI+S+G Sbjct: 135 LIDKSGLIKVADFGLGRSF-GIPVRIYTHEI-VTLWYRAPEVLLGSPRYSCPVDIWSIGC 192 Query: 487 IIIEILTGK 461 I E+ T K Sbjct: 193 IFAEMATRK 201 Score = 27.3 bits (59), Expect(2) = 2e-04 Identities = 9/17 (52%), Positives = 13/17 (76%) Frame = -2 Query: 707 HQRNILHLDLKPANIFV 657 H+R +LH DLKP N+ + Sbjct: 120 HRRRVLHRDLKPQNLLI 136
>KRAF1_DROME (P11346) Raf homolog serine/threonine-protein kinase dRAF-1 (EC| 2.7.11.1) (Protein pole-hole) Length = 739 Score = 36.2 bits (82), Expect(2) = 3e-04 Identities = 36/170 (21%), Positives = 69/170 (40%), Gaps = 9/170 (5%) Frame = -3 Query: 658 LDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGE----ITYQLDIYSVG 491 L +L KI DFG++ G++ ++APE + ++Q D+Y+ G Sbjct: 556 LHEDLSVKIGDFGLATAKTRWSGEKQANQPTGSILWMAPEVIRMQELNPYSFQSDVYAFG 615 Query: 490 VIIIEILTGKKGYLAVDN----VVESWSNKLEKSQSDVQLKQVRICAEIGIECTDFNPAK 323 +++ E+L Y + N + L S V+ + + +C + P Sbjct: 616 IVMYELLAECLPYGHISNKDQILFMVGRGLLRPDMSQVRSDAPQALKRLAEDCIKYTPKD 675 Query: 322 RPGTKNIIDRLVSLDET-DSMGGYIETSAVTSQQAENALEELHQARPKVP 176 RP + +++ L ++ T + +T Q +N E L+ PK P Sbjct: 676 RPLFRPLLNMLENMLRTLPKIHRSASEPNLTQSQLQND-EFLYLPSPKTP 724 Score = 27.7 bits (60), Expect(2) = 3e-04 Identities = 11/18 (61%), Positives = 14/18 (77%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 LH +NI+H DLK NIF+ Sbjct: 539 LHAKNIIHRDLKSNNIFL 556
>NEK8_BRARE (Q90XC2) Serine/threonine-protein kinase Nek8 (EC 2.7.11.1)| (NimA-related protein kinase 8) Length = 697 Score = 41.6 bits (96), Expect(2) = 3e-04 Identities = 35/165 (21%), Positives = 78/165 (47%), Gaps = 2/165 (1%) Frame = -3 Query: 661 LLDGN-LVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGE-ITYQLDIYSVGV 488 LLD + ++ KI DFG+S+ + S++ + GT Y++PE C G+ + DI+++G Sbjct: 135 LLDKHQMIVKIGDFGISKI---LVSKSKAYTVVGTPCYISPELCEGKPYNQKSDIWALGC 191 Query: 487 IIIEILTGKKGYLAVDNVVESWSNKLEKSQSDVQLKQVRICAEIGIECTDFNPAKRPGTK 308 ++ E+ + K+ + A N+ + + + + + ++ + + +P+KRP Sbjct: 192 VLYELASLKRAFEAA-NLPALVLKIMSGTFAPISDRYSPELRQLILNMLNLDPSKRPQLN 250 Query: 307 NIIDRLVSLDETDSMGGYIETSAVTSQQAENALEELHQARPKVPG 173 I+ + + ++ Y + V ++ E L + PG Sbjct: 251 EIMAHAICIRPLLNL--YTDIGNVKMRRIEKPLSNVQAGPHGRPG 293 Score = 22.3 bits (46), Expect(2) = 3e-04 Identities = 9/18 (50%), Positives = 12/18 (66%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 +H + ILH DLK NI + Sbjct: 119 VHNKLILHRDLKTQNILL 136
>PKSC_STRCO (Q9S2C0) Serine/threonine protein kinase pksC (EC 2.7.11.1)| Length = 556 Score = 40.8 bits (94), Expect(2) = 3e-04 Identities = 22/63 (34%), Positives = 38/63 (60%), Gaps = 2/63 (3%) Frame = -3 Query: 643 VPKIADFGVSRCFHE-MQSRAITVNIRGTLGYLAPEFCNGE-ITYQLDIYSVGVIIIEIL 470 V K+ DFG++R + S T + GT YL+PE G + + D+YSVG+++ +++ Sbjct: 164 VVKVMDFGIARAMQSGVTSMTQTGMVVGTPQYLSPEQALGRGVDARSDLYSVGIMLFQLV 223 Query: 469 TGK 461 TG+ Sbjct: 224 TGR 226 Score = 23.1 bits (48), Expect(2) = 3e-04 Identities = 6/17 (35%), Positives = 12/17 (70%) Frame = -2 Query: 707 HQRNILHLDLKPANIFV 657 H+ ++H D+KP N+ + Sbjct: 143 HEMGLVHRDIKPGNVMM 159
>M3KSL_DROME (Q95UN8) Mitogen-activated protein kinase kinase kinase (EC| 2.7.11.25) (Mixed lineage kinase) (dMLK) (Protein slipper) Length = 1161 Score = 44.7 bits (104), Expect = 3e-04 Identities = 32/121 (26%), Positives = 57/121 (47%), Gaps = 2/121 (1%) Frame = -3 Query: 637 KIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEITYQL--DIYSVGVIIIEILTG 464 KI DFG++R + Q ++ GT ++ PE + TY D++S GV++ E++TG Sbjct: 287 KITDFGLAREMYNTQR----MSAAGTYAWMPPEVISVS-TYSKFSDVWSYGVLLWELITG 341 Query: 463 KKGYLAVDNVVESWSNKLEKSQSDVQLKQVRICAEIGIECTDFNPAKRPGTKNIIDRLVS 284 + Y D + ++ + + + C +P KRPG K I+ +L S Sbjct: 342 ETPYKGFDPLSVAYGVAVNTLTLPIPKTCPETWGALMKSCWQTDPHKRPGFKEILKQLES 401 Query: 283 L 281 + Sbjct: 402 I 402
>FGFR4_HUMAN (P22455) Fibroblast growth factor receptor 4 precursor (EC| 2.7.10.1) (FGFR-4) (CD334 antigen) Length = 802 Score = 44.7 bits (104), Expect = 3e-04 Identities = 39/129 (30%), Positives = 63/129 (48%), Gaps = 2/129 (1%) Frame = -3 Query: 670 RTYLLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEI-TYQLDIYSV 494 R L+ + V KIADFG++R H + T N R + ++APE + T+Q D++S Sbjct: 616 RNVLVTEDNVMKIADFGLARGVHHIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSF 675 Query: 493 GVIIIEILT-GKKGYLAVDNVVESWSNKLEKSQSDVQLKQVRICAEIGIECTDFNPAKRP 317 G+++ EI T G Y + V E +S E + D + EC P++RP Sbjct: 676 GILLWEIFTLGGSPYPGIP-VEELFSLLREGHRMDRPPHCPPELYGLMRECWHAAPSQRP 734 Query: 316 GTKNIIDRL 290 K +++ L Sbjct: 735 TFKQLVEAL 743
>YRK_CHICK (Q02977) Proto-oncogene tyrosine-protein kinase Yrk (EC 2.7.10.2)| (p60-Yrk) (Yes-related kinase) Length = 535 Score = 40.0 bits (92), Expect(2) = 3e-04 Identities = 32/121 (26%), Positives = 62/121 (51%), Gaps = 6/121 (4%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFC-NGEITYQLDIYSVGVI 485 L+ NLV KIADFG++R + + A + + + APE G+ T + D++S G++ Sbjct: 395 LVGDNLVCKIADFGLARLIEDNEYTA-RQGAKFPIKWTAPEAALFGKFTIKSDVWSFGIL 453 Query: 484 IIEILT-GKKGYLAVDNVVESWSNKLEKSQSDVQLKQVRICA----EIGIECTDFNPAKR 320 + E++T G+ Y ++N LE+ + +++ C ++ ++C P +R Sbjct: 454 LTELVTKGRVPYPGMNN-----REVLEQVERGYRMQCPGGCPPSLHDVMVQCWKREPEER 508 Query: 319 P 317 P Sbjct: 509 P 509 Score = 23.9 bits (50), Expect(2) = 3e-04 Identities = 9/19 (47%), Positives = 13/19 (68%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFVG 654 + + N +H DL+ ANI VG Sbjct: 379 IERMNYIHRDLRAANILVG 397
>CDC2_BOVIN (P48734) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 37.0 bits (84), Expect(2) = 3e-04 Identities = 26/69 (37%), Positives = 37/69 (53%), Gaps = 2/69 (2%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEITYQ--LDIYSVGV 488 L+D K+ADFG++R F + R T + TL Y +PE G Y +DI+S+G Sbjct: 135 LIDDKGTIKLADFGLARAF-GIPIRVYTHEV-VTLWYRSPEVLLGSAGYSTPVDIWSIGT 192 Query: 487 IIIEILTGK 461 I E+ T K Sbjct: 193 IFAELATKK 201 Score = 26.9 bits (58), Expect(2) = 3e-04 Identities = 9/17 (52%), Positives = 12/17 (70%) Frame = -2 Query: 707 HQRNILHLDLKPANIFV 657 H R +LH DLKP N+ + Sbjct: 120 HSRRVLHRDLKPQNLLI 136
>CDC2H_PLAYO (Q7RM49) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 289 Score = 38.1 bits (87), Expect(2) = 3e-04 Identities = 25/61 (40%), Positives = 36/61 (59%), Gaps = 2/61 (3%) Frame = -3 Query: 637 KIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEITYQ--LDIYSVGVIIIEILTG 464 KIADFG++R F + +R T + TL Y AP+ G Y +DI+SVG I E++ G Sbjct: 141 KIADFGLARAFG-IPARRYTHEVV-TLWYRAPDILMGSKKYSTPIDIWSVGCIFAEMVNG 198 Query: 463 K 461 + Sbjct: 199 R 199 Score = 25.8 bits (55), Expect(2) = 3e-04 Identities = 8/17 (47%), Positives = 12/17 (70%) Frame = -2 Query: 707 HQRNILHLDLKPANIFV 657 H+ +LH DLKP N+ + Sbjct: 118 HEHRVLHRDLKPQNLLI 134
>CDC2H_PLACH (Q4Y4B1) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 288 Score = 38.1 bits (87), Expect(2) = 3e-04 Identities = 25/61 (40%), Positives = 36/61 (59%), Gaps = 2/61 (3%) Frame = -3 Query: 637 KIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEITYQ--LDIYSVGVIIIEILTG 464 KIADFG++R F + +R T + TL Y AP+ G Y +DI+SVG I E++ G Sbjct: 140 KIADFGLARAFG-IPARRYTHEVV-TLWYRAPDILMGSKKYSTPIDIWSVGCIFAEMVNG 197 Query: 463 K 461 + Sbjct: 198 R 198 Score = 25.8 bits (55), Expect(2) = 3e-04 Identities = 8/17 (47%), Positives = 12/17 (70%) Frame = -2 Query: 707 HQRNILHLDLKPANIFV 657 H+ +LH DLKP N+ + Sbjct: 117 HEHRVLHRDLKPQNLLI 133
>CDC2H_PLABA (Q4Z6R1) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 288 Score = 38.1 bits (87), Expect(2) = 3e-04 Identities = 25/61 (40%), Positives = 36/61 (59%), Gaps = 2/61 (3%) Frame = -3 Query: 637 KIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEITYQ--LDIYSVGVIIIEILTG 464 KIADFG++R F + +R T + TL Y AP+ G Y +DI+SVG I E++ G Sbjct: 140 KIADFGLARAFG-IPARRYTHEVV-TLWYRAPDILMGSKKYSTPIDIWSVGCIFAEMVNG 197 Query: 463 K 461 + Sbjct: 198 R 198 Score = 25.8 bits (55), Expect(2) = 3e-04 Identities = 8/17 (47%), Positives = 12/17 (70%) Frame = -2 Query: 707 HQRNILHLDLKPANIFV 657 H+ +LH DLKP N+ + Sbjct: 117 HEHRVLHRDLKPQNLLI 133
>KS6A_CAEEL (Q21734) Putative ribosomal protein S6 kinase alpha (EC 2.7.11.1)| Length = 784 Score = 40.8 bits (94), Expect(2) = 4e-04 Identities = 25/67 (37%), Positives = 39/67 (58%), Gaps = 1/67 (1%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGE-ITYQLDIYSVGVI 485 LLD + K+ DFG+S+ + S T + GT+ Y+APE N + D +S+GV+ Sbjct: 236 LLDADGHIKVTDFGLSK--EAIDSEKKTYSFCGTVEYMAPEVINRRGHSMAADFWSLGVL 293 Query: 484 IIEILTG 464 + E+LTG Sbjct: 294 MFEMLTG 300 Score = 22.7 bits (47), Expect(2) = 4e-04 Identities = 9/18 (50%), Positives = 12/18 (66%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 LH I++ DLKP NI + Sbjct: 220 LHSLGIVYRDLKPENILL 237
>PLO1_SCHPO (P50528) Serine/threonine-protein kinase plo1 (EC 2.7.11.21)| Length = 683 Score = 40.8 bits (94), Expect(2) = 4e-04 Identities = 37/128 (28%), Positives = 64/128 (50%), Gaps = 6/128 (4%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGE---ITYQLDIYSVG 491 +LD + KI DFG++ + + R +T I GT Y+APE ++++D++S G Sbjct: 170 MLDESNNVKIGDFGLAALLMDDEERKMT--ICGTPNYIAPEILFNSKEGHSFEVDLWSAG 227 Query: 490 VIIIEILTGKKGYLAVDNVVESWSNKLEKSQSDVQLKQVRICAE---IGIECTDFNPAKR 320 V++ +L GK + D V++ K+ K+ S V I AE + +P+ R Sbjct: 228 VVMYALLIGKPPF--QDKEVKTIYRKI-KANSYSFPSNVDISAEAKDLISSLLTHDPSIR 284 Query: 319 PGTKNIID 296 P +I+D Sbjct: 285 PSIDDIVD 292 Score = 22.7 bits (47), Expect(2) = 4e-04 Identities = 7/18 (38%), Positives = 13/18 (72%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 +H++ ++H DLK NI + Sbjct: 154 MHKKRVIHRDLKLGNIML 171
>BYR2_SCHPO (P28829) Protein kinase byr2 (EC 2.7.11.25) (Protein kinase ste8)| (MAPK kinase kinase) (MAPKKK) Length = 659 Score = 37.0 bits (84), Expect(2) = 4e-04 Identities = 26/81 (32%), Positives = 42/81 (51%), Gaps = 5/81 (6%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIR----GTLGYLAPEFCNGEI-TYQLDIYS 497 L+D KI+DFG+S+ + T R G+ ++APE + T + DI+S Sbjct: 529 LVDNKGKIKISDFGISKKLELNSTSTKTGGARPSFQGSSFWMAPEVVKQTMHTEKTDIWS 588 Query: 496 VGVIIIEILTGKKGYLAVDNV 434 +G ++IE+LT K Y D + Sbjct: 589 LGCLVIEMLTSKHPYPNCDQM 609 Score = 26.6 bits (57), Expect(2) = 4e-04 Identities = 11/18 (61%), Positives = 13/18 (72%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 LH R I+H D+K ANI V Sbjct: 513 LHSRGIVHRDIKGANILV 530
>M3K3_ARATH (O22042) Mitogen-activated protein kinase kinase kinase 3 (EC| 2.7.11.25) (Arabidospsis NPK1-related protein kinase 3) Length = 651 Score = 38.5 bits (88), Expect(2) = 4e-04 Identities = 23/68 (33%), Positives = 39/68 (57%), Gaps = 1/68 (1%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPE-FCNGEITYQLDIYSVGVI 485 L+D ++ADFG S+ E+ + +++GT ++APE ++ DI+SVG Sbjct: 203 LVDNKGCIRLADFGASKKVVELATVNGAKSMKGTPYWMAPEVILQTGHSFSADIWSVGCT 262 Query: 484 IIEILTGK 461 +IE+ TGK Sbjct: 263 VIEMATGK 270 Score = 25.0 bits (53), Expect(2) = 4e-04 Identities = 10/18 (55%), Positives = 12/18 (66%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 LH I+H D+K ANI V Sbjct: 187 LHNNGIMHRDIKGANILV 204
>CHK1_CAEBR (Q61RA2) Serine/threonine-protein kinase chk-1 (EC 2.7.11.1)| Length = 493 Score = 40.8 bits (94), Expect(2) = 4e-04 Identities = 26/71 (36%), Positives = 46/71 (64%), Gaps = 4/71 (5%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCF-HEMQSRAITVNIRGTLGYLAPEFCNGEITYQ---LDIYSV 494 LL + V KI+DFG++ + +E + R + ++ GT+ Y APE C G Y+ +D++S Sbjct: 157 LLTTSHVLKISDFGMATLYRNEGKERLLDLSC-GTIPYAAPEVCAGG-KYRGPPIDVWSS 214 Query: 493 GVIIIEILTGK 461 G+++I +LTG+ Sbjct: 215 GIVLIAMLTGE 225 Score = 22.7 bits (47), Expect(2) = 4e-04 Identities = 7/18 (38%), Positives = 13/18 (72%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 +H +I+H D+KP N+ + Sbjct: 141 IHDCDIVHRDIKPENLLL 158
>PMYT1_MOUSE (Q9ESG9) Membrane-associated tyrosine- and threonine-specific| cdc2-inhibitory kinase (EC 2.7.11.1) (Myt1 kinase) Length = 490 Score = 33.1 bits (74), Expect(2) = 4e-04 Identities = 12/19 (63%), Positives = 17/19 (89%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFVG 654 LH + ++HLD+KPANIF+G Sbjct: 215 LHSQGLVHLDVKPANIFLG 233 Score = 30.4 bits (67), Expect(2) = 4e-04 Identities = 17/55 (30%), Positives = 27/55 (49%) Frame = -3 Query: 637 KIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEITYQLDIYSVGVIIIEI 473 K+ DFG+ E+ S G Y+APE G D++S+G+ I+E+ Sbjct: 239 KLGDFGL---LVELGSTGAGEAQEGDPRYMAPELLQGSYGTAADVFSLGLTILEV 290
>KCC2_YEAST (P22517) Calcium/calmodulin-dependent protein kinase II (EC| 2.7.11.17) Length = 447 Score = 36.6 bits (83), Expect(2) = 4e-04 Identities = 34/121 (28%), Positives = 55/121 (45%), Gaps = 8/121 (6%) Frame = -3 Query: 634 IADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEITYQ-LDIYSVGVIIIEILTGKK 458 IADFG+++ + + G+LGY+APE + + DI+S+GVI +L G Sbjct: 190 IADFGIAKQLKGEED--LIYKAAGSLGYVAPEVLTQDGHGKPCDIWSIGVITYTLLCGYS 247 Query: 457 GYLAVDNVVESWSNKLEKSQSDVQLKQVRICAEIGIECTDF-------NPAKRPGTKNII 299 ++A VE + + S+ V + I I+ F NPA RP ++ Sbjct: 248 PFIA--ESVEGFMEECTASRYPVTF-HMPYWDNISIDVKRFILKALRLNPADRPTATELL 304 Query: 298 D 296 D Sbjct: 305 D 305 Score = 26.9 bits (58), Expect(2) = 4e-04 Identities = 8/16 (50%), Positives = 13/16 (81%) Frame = -2 Query: 710 LHQRNILHLDLKPANI 663 +H +N++H DLKP N+ Sbjct: 162 MHSKNVVHRDLKPENV 177
>IPL1_CANGA (Q6FV07) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 358 Score = 35.0 bits (79), Expect(2) = 4e-04 Identities = 22/61 (36%), Positives = 34/61 (55%), Gaps = 1/61 (1%) Frame = -3 Query: 643 VPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNG-EITYQLDIYSVGVIIIEILT 467 V K+ADFG S E R + GT+ YL+PE E Q+D++++GV+ E++ Sbjct: 236 VVKLADFGWSILNPEGSKRK---TLCGTIDYLSPEMITPREYDEQVDVWALGVLAYELVV 292 Query: 466 G 464 G Sbjct: 293 G 293 Score = 28.5 bits (62), Expect(2) = 4e-04 Identities = 8/20 (40%), Positives = 16/20 (80%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFVGW 651 +H++ I+H D+KP N+ +G+ Sbjct: 214 MHKKRIIHRDVKPENVLIGF 233
>CD2L5_HUMAN (Q14004) Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22)| (CDC2-related protein kinase 5) (Cholinesterase-related cell division controller) Length = 1512 Score = 39.7 bits (91), Expect(2) = 5e-04 Identities = 24/61 (39%), Positives = 35/61 (57%), Gaps = 2/61 (3%) Frame = -3 Query: 637 KIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEITY--QLDIYSVGVIIIEILTG 464 K+ADFG++R + +SR T + TL Y PE GE Y +D++S G I+ E+ T Sbjct: 852 KLADFGLARLYSSEESRPYTNKVI-TLWYRPPELLLGEERYTPAIDVWSCGCILGELFTK 910 Query: 463 K 461 K Sbjct: 911 K 911 Score = 23.5 bits (49), Expect(2) = 5e-04 Identities = 8/17 (47%), Positives = 13/17 (76%) Frame = -2 Query: 707 HQRNILHLDLKPANIFV 657 H++N LH D+K +NI + Sbjct: 829 HKKNFLHRDIKCSNILL 845
>CD2L5_MOUSE (Q69ZA1) Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22)| (CDC2-related protein kinase 5) Length = 1511 Score = 39.7 bits (91), Expect(2) = 5e-04 Identities = 24/61 (39%), Positives = 35/61 (57%), Gaps = 2/61 (3%) Frame = -3 Query: 637 KIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEITY--QLDIYSVGVIIIEILTG 464 K+ADFG++R + +SR T + TL Y PE GE Y +D++S G I+ E+ T Sbjct: 852 KLADFGLARLYSSEESRPYTNKVI-TLWYRPPELLLGEERYTPAIDVWSCGCILGELFTK 910 Query: 463 K 461 K Sbjct: 911 K 911 Score = 23.5 bits (49), Expect(2) = 5e-04 Identities = 8/17 (47%), Positives = 13/17 (76%) Frame = -2 Query: 707 HQRNILHLDLKPANIFV 657 H++N LH D+K +NI + Sbjct: 829 HKKNFLHRDIKCSNILL 845
>GIN4_YEAST (Q12263) Serine/threonine-protein kinase GIN4 (EC 2.7.11.1)| Length = 1142 Score = 40.4 bits (93), Expect(2) = 5e-04 Identities = 38/131 (29%), Positives = 64/131 (48%), Gaps = 10/131 (7%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEITYQ---LDIYSVG 491 LLD KIADFG++ E + + + + G+ Y APE +G I YQ D++S G Sbjct: 163 LLDHKYNIKIADFGMAAL--ETEGKLLETSC-GSPHYAAPEIVSG-IPYQGFASDVWSCG 218 Query: 490 VIIIEILTGKKGYLAVDNVVESWSNKLEKSQSDVQLKQVRICAEIGIECTDF-------N 332 VI+ +LTG+ + D + + K++K + ++ EI E D + Sbjct: 219 VILFALLTGRLPFDEEDGNIRTLLLKVQKGEFEMPSDD-----EISREAQDLIRKILTVD 273 Query: 331 PAKRPGTKNII 299 P +R T++I+ Sbjct: 274 PERRIKTRDIL 284 Score = 22.7 bits (47), Expect(2) = 5e-04 Identities = 8/21 (38%), Positives = 13/21 (61%) Frame = -2 Query: 707 HQRNILHLDLKPANIFVGWQF 645 H I+H DLKP N+ + ++ Sbjct: 148 HALGIVHRDLKPENLLLDHKY 168
>CDC15_YEAST (P27636) Cell division control protein 15 (EC 2.7.11.1)| Length = 974 Score = 40.0 bits (92), Expect(2) = 5e-04 Identities = 27/71 (38%), Positives = 39/71 (54%), Gaps = 1/71 (1%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEITYQL-DIYSVGVI 485 LL + K+ADFGVS + S A+T + GTL ++APE L DI+S+G Sbjct: 153 LLSADNTVKLADFGVSTI---VNSSALT--LAGTLNWMAPEILGNRGASTLSDIWSLGAT 207 Query: 484 IIEILTGKKGY 452 ++E+LT Y Sbjct: 208 VVEMLTKNPPY 218 Score = 23.1 bits (48), Expect(2) = 5e-04 Identities = 8/18 (44%), Positives = 12/18 (66%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 LH ++H D+K ANI + Sbjct: 137 LHGEGVIHRDIKAANILL 154
>NEK8_MOUSE (Q91ZR4) Serine/threonine-protein kinase Nek8 (EC 2.7.11.1) (Never| in mitosis A-related kinase 8) (NimA-related protein kinase 8) Length = 698 Score = 42.0 bits (97), Expect(2) = 5e-04 Identities = 24/76 (31%), Positives = 46/76 (60%), Gaps = 2/76 (2%) Frame = -3 Query: 661 LLDGN-LVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGE-ITYQLDIYSVGV 488 LLD + +V KI DFG+S+ + S++ + GT Y++PE C G+ + DI+++G Sbjct: 135 LLDKHRMVVKIGDFGISKI---LSSKSKAYTVVGTPCYISPELCEGKPYNQKSDIWALGC 191 Query: 487 IIIEILTGKKGYLAVD 440 ++ E+ + K+ + A + Sbjct: 192 VLYELASLKRAFEAAN 207 Score = 21.2 bits (43), Expect(2) = 5e-04 Identities = 9/18 (50%), Positives = 11/18 (61%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 +H ILH DLK NI + Sbjct: 119 VHTHLILHRDLKTQNILL 136
>NEK8_HUMAN (Q86SG6) Serine/threonine-protein kinase Nek8 (EC 2.7.11.1) (Never| in mitosis A-related kinase 8) (NimA-related protein kinase 8) (NIMA-related kinase 12a) Length = 692 Score = 42.0 bits (97), Expect(2) = 5e-04 Identities = 24/76 (31%), Positives = 46/76 (60%), Gaps = 2/76 (2%) Frame = -3 Query: 661 LLDGN-LVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGE-ITYQLDIYSVGV 488 LLD + +V KI DFG+S+ + S++ + GT Y++PE C G+ + DI+++G Sbjct: 135 LLDKHRMVVKIGDFGISKI---LSSKSKAYTVVGTPCYISPELCEGKPYNQKSDIWALGC 191 Query: 487 IIIEILTGKKGYLAVD 440 ++ E+ + K+ + A + Sbjct: 192 VLYELASLKRAFEAAN 207 Score = 21.2 bits (43), Expect(2) = 5e-04 Identities = 9/18 (50%), Positives = 11/18 (61%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 +H ILH DLK NI + Sbjct: 119 VHTHLILHRDLKTQNILL 136
>RIPK1_MOUSE (Q60855) Receptor-interacting serine/threonine-protein kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein) Length = 656 Score = 34.7 bits (78), Expect(2) = 5e-04 Identities = 30/92 (32%), Positives = 45/92 (48%), Gaps = 15/92 (16%) Frame = -3 Query: 661 LLDGNLVPKIADFGV------SRCFHEMQSRAITV------NIRGTLGYLAPEFCN---G 527 L+D + KIAD GV S+ E ++ V N GTL Y+APE N Sbjct: 145 LVDRDFHIKIADLGVASFKTWSKLTKEKDNKQKEVSSTTKKNNGGTLYYMAPEHLNDINA 204 Query: 526 EITYQLDIYSVGVIIIEILTGKKGYLAVDNVV 431 + T + D+YS G+++ I K+ Y +NV+ Sbjct: 205 KPTEKSDVYSFGIVLWAIFAKKEPY---ENVI 233 Score = 28.5 bits (62), Expect(2) = 5e-04 Identities = 11/22 (50%), Positives = 14/22 (63%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFVGWQF 645 LH + ++H DLKP NI V F Sbjct: 129 LHDKGVIHKDLKPENILVDRDF 150
>KSG1_SCHPO (Q12701) Serine/threonine-protein kinase ksg1 (EC 2.7.11.1)| Length = 592 Score = 37.0 bits (84), Expect(2) = 5e-04 Identities = 25/85 (29%), Positives = 43/85 (50%), Gaps = 13/85 (15%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCF------------HEMQSRAITVNIRGTLGYLAPEFCNGEIT 518 LLD N+ KI DFG ++ H + +A + + GT Y++PE + +I Sbjct: 230 LLDDNMRTKITDFGSAKILNSSHGSHEEDTHHADKPQAHSRSFVGTARYVSPEVLSDKIA 289 Query: 517 -YQLDIYSVGVIIIEILTGKKGYLA 446 DI++ G I+ ++L GK ++A Sbjct: 290 GTASDIWAFGCILFQMLAGKPPFVA 314 Score = 26.2 bits (56), Expect(2) = 5e-04 Identities = 9/18 (50%), Positives = 13/18 (72%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 +H R ++H DLKP NI + Sbjct: 214 MHGRGVIHRDLKPENILL 231
>SHK2_SCHPO (Q10056) Serine/threonine-protein kinase shk2 (EC 2.7.11.1)| Length = 589 Score = 37.7 bits (86), Expect(2) = 5e-04 Identities = 25/77 (32%), Positives = 42/77 (54%), Gaps = 1/77 (1%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCN-GEITYQLDIYSVGVI 485 LLD + KI DFG ++ +T+ GT ++APE E ++DI+S+G++ Sbjct: 441 LLDNSGNIKITDFGFCARLSNRTNKRVTMV--GTPYWMAPEVVKQNEYGTKVDIWSLGIM 498 Query: 484 IIEILTGKKGYLAVDNV 434 IIE++ + YL D + Sbjct: 499 IIEMIENEPPYLREDPI 515 Score = 25.4 bits (54), Expect(2) = 5e-04 Identities = 9/18 (50%), Positives = 13/18 (72%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 LH RNI+H D+K N+ + Sbjct: 425 LHARNIIHRDIKSDNVLL 442
>FYN_HUMAN (P06241) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) (Protooncogene Syn) (SLK) Length = 536 Score = 39.3 bits (90), Expect(2) = 5e-04 Identities = 32/121 (26%), Positives = 60/121 (49%), Gaps = 6/121 (4%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFC-NGEITYQLDIYSVGVI 485 L+ L+ KIADFG++R + + A + + + APE G T + D++S G++ Sbjct: 396 LVGNGLICKIADFGLARLIEDNEYTA-RQGAKFPIKWTAPEAALYGRFTIKSDVWSFGIL 454 Query: 484 IIEILT-GKKGYLAVDNVVESWSNKLEKSQSDVQLKQVRICA----EIGIECTDFNPAKR 320 + E++T G+ Y ++N LE+ + ++ + C E+ I C +P +R Sbjct: 455 LTELVTKGRVPYPGMNN-----REVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEER 509 Query: 319 P 317 P Sbjct: 510 P 510 Score = 23.9 bits (50), Expect(2) = 5e-04 Identities = 9/19 (47%), Positives = 13/19 (68%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFVG 654 + + N +H DL+ ANI VG Sbjct: 380 IERMNYIHRDLRSANILVG 398
>SPKC_SYNY3 (P74745) Serine/threonine-protein kinase C (EC 2.7.11.1)| Length = 535 Score = 35.0 bits (79), Expect(2) = 5e-04 Identities = 19/44 (43%), Positives = 26/44 (59%), Gaps = 1/44 (2%) Frame = -3 Query: 565 GTLGYLAPEFCNGEITYQLDIYSVGVIIIEILTGK-KGYLAVDN 437 GT GY+A E G + D+YS+G+ I +LTGK YL D+ Sbjct: 186 GTPGYMASEQAAGRPVFSSDLYSLGLTAIFLLTGKTPQYLTSDS 229 Score = 28.1 bits (61), Expect(2) = 5e-04 Identities = 10/18 (55%), Positives = 14/18 (77%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFV 657 +HQR I+H D+KP NI + Sbjct: 133 IHQRRIIHRDIKPDNIIL 150
>FYN_MOUSE (P39688) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 533 Score = 39.3 bits (90), Expect(2) = 5e-04 Identities = 32/121 (26%), Positives = 60/121 (49%), Gaps = 6/121 (4%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFC-NGEITYQLDIYSVGVI 485 L+ L+ KIADFG++R + + A + + + APE G T + D++S G++ Sbjct: 393 LVGNGLICKIADFGLARLIEDNEYTA-RQGAKFPIKWTAPEAALYGRFTIKSDVWSFGIL 451 Query: 484 IIEILT-GKKGYLAVDNVVESWSNKLEKSQSDVQLKQVRICA----EIGIECTDFNPAKR 320 + E++T G+ Y ++N LE+ + ++ + C E+ I C +P +R Sbjct: 452 LTELVTKGRVPYPGMNN-----REVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEER 506 Query: 319 P 317 P Sbjct: 507 P 507 Score = 23.9 bits (50), Expect(2) = 5e-04 Identities = 9/19 (47%), Positives = 13/19 (68%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFVG 654 + + N +H DL+ ANI VG Sbjct: 377 IERMNYIHRDLRSANILVG 395
>FYN_CHICK (Q05876) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 533 Score = 39.3 bits (90), Expect(2) = 5e-04 Identities = 32/121 (26%), Positives = 60/121 (49%), Gaps = 6/121 (4%) Frame = -3 Query: 661 LLDGNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFC-NGEITYQLDIYSVGVI 485 L+ L+ KIADFG++R + + A + + + APE G T + D++S G++ Sbjct: 393 LVGNGLICKIADFGLARLIEDNEYTA-RQGAKFPIKWTAPEAALYGRFTIKSDVWSFGIL 451 Query: 484 IIEILT-GKKGYLAVDNVVESWSNKLEKSQSDVQLKQVRICA----EIGIECTDFNPAKR 320 + E++T G+ Y ++N LE+ + ++ + C E+ I C +P +R Sbjct: 452 LTELVTKGRVPYPGMNN-----REVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEER 506 Query: 319 P 317 P Sbjct: 507 P 507 Score = 23.9 bits (50), Expect(2) = 5e-04 Identities = 9/19 (47%), Positives = 13/19 (68%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFVG 654 + + N +H DL+ ANI VG Sbjct: 377 IERMNYIHRDLRSANILVG 395
>PMYT1_DROME (Q9NI63) Membrane-associated tyrosine- and threonine-specific| cdc2-inhibitory kinase (EC 2.7.11.1) (Myt1 kinase) (dMyt1) Length = 533 Score = 33.5 bits (75), Expect(2) = 5e-04 Identities = 18/55 (32%), Positives = 28/55 (50%) Frame = -3 Query: 637 KIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNGEITYQLDIYSVGVIIIEI 473 K+ADFG+ S T G Y+APE G + DI+S+G+ ++E+ Sbjct: 240 KLADFGLVIDVDRANSHHAT---EGDSRYMAPEILQGHFSKAADIFSLGIAMLEL 291 Score = 29.6 bits (65), Expect(2) = 5e-04 Identities = 10/19 (52%), Positives = 15/19 (78%) Frame = -2 Query: 710 LHQRNILHLDLKPANIFVG 654 LH RN++HLD+K N+ +G Sbjct: 215 LHDRNLIHLDIKLDNVLIG 233
>KCC4_RAT (P13234) Calcium/calmodulin-dependent protein kinase type IV (EC| 2.7.11.17) (CAM kinase-GR) (CaMK IV) (Calspermin) Length = 474 Score = 37.7 bits (86), Expect(2) = 5e-04 Identities = 22/59 (37%), Positives = 35/59 (59%), Gaps = 1/59 (1%) Frame = -3 Query: 637 KIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNG-EITYQLDIYSVGVIIIEILTG 464 KIADFG+S+ ++ + + + GT GY APE G ++D++SVG+I +L G Sbjct: 178 KIADFGLSKI---VEHQVLMKTVCGTPGYCAPEILRGCAYGPEVDMWSVGIITYILLCG 233 Score = 25.4 bits (54), Expect(2) = 5e-04 Identities = 9/16 (56%), Positives = 12/16 (75%) Frame = -2 Query: 710 LHQRNILHLDLKPANI 663 LH+ I+H DLKP N+ Sbjct: 151 LHENGIVHRDLKPENL 166
>KCC4_HUMAN (Q16566) Calcium/calmodulin-dependent protein kinase type IV (EC| 2.7.11.17) (CAM kinase-GR) (CaMK IV) Length = 473 Score = 37.7 bits (86), Expect(2) = 5e-04 Identities = 22/59 (37%), Positives = 35/59 (59%), Gaps = 1/59 (1%) Frame = -3 Query: 637 KIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNG-EITYQLDIYSVGVIIIEILTG 464 KIADFG+S+ ++ + + + GT GY APE G ++D++SVG+I +L G Sbjct: 182 KIADFGLSKI---VEHQVLMKTVCGTPGYCAPEILRGCAYGPEVDMWSVGIITYILLCG 237 Score = 25.4 bits (54), Expect(2) = 5e-04 Identities = 9/16 (56%), Positives = 12/16 (75%) Frame = -2 Query: 710 LHQRNILHLDLKPANI 663 LH+ I+H DLKP N+ Sbjct: 155 LHENGIVHRDLKPENL 170
>KCC4_MOUSE (P08414) Calcium/calmodulin-dependent protein kinase type IV (EC| 2.7.11.17) (CAM kinase-GR) (CaMK IV) Length = 469 Score = 37.7 bits (86), Expect(2) = 5e-04 Identities = 22/59 (37%), Positives = 35/59 (59%), Gaps = 1/59 (1%) Frame = -3 Query: 637 KIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFCNG-EITYQLDIYSVGVIIIEILTG 464 KIADFG+S+ ++ + + + GT GY APE G ++D++SVG+I +L G Sbjct: 178 KIADFGLSKI---VEHQVLMKTVCGTPGYCAPEILRGCAYGPEVDMWSVGIITYILLCG 233 Score = 25.4 bits (54), Expect(2) = 5e-04 Identities = 9/16 (56%), Positives = 12/16 (75%) Frame = -2 Query: 710 LHQRNILHLDLKPANI 663 LH+ I+H DLKP N+ Sbjct: 151 LHENGIVHRDLKPENL 166
>CPK15_ARATH (P92937) CBL-interacting serine/threonine-protein kinase 15 (EC| 2.7.11.1) (Serine/threonine-protein kinase ATPK10) (SOS2-like protein kinase PKS3) (SOS-interacting protein 2) (SNF1-related kinase 3.1) Length = 421 Score = 38.9 bits (89), Expect(2) = 5e-04 Identities = 27/70 (38%), Positives = 38/70 (54%), Gaps = 4/70 (5%) Frame = -3 Query: 661 LLD--GNLVPKIADFGVSRCFHEMQSRAITVNIRGTLGYLAPEFC--NGEITYQLDIYSV 494 LLD GNL KI+DFG+S + + GT Y+APE NG ++ D++S Sbjct: 141 LLDEHGNL--KISDFGLSALSDSRRQDGLLHTTCGTPAYVAPEVISRNGYDGFKADVWSC 198 Query: 493 GVIIIEILTG 464 GVI+ +L G Sbjct: 199 GVILFVLLAG 208 Score = 24.3 bits (51), Expect(2) = 5e-04 Identities = 8/17 (47%), Positives = 11/17 (64%) Frame = -2 Query: 707 HQRNILHLDLKPANIFV 657 H R + H DLKP N+ + Sbjct: 126 HSRGVCHRDLKPENLLL 142 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 102,410,071 Number of Sequences: 219361 Number of extensions: 2110858 Number of successful extensions: 7566 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 6431 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 7409 length of database: 80,573,946 effective HSP length: 109 effective length of database: 56,663,597 effective search space used: 7196276819 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
