ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | rbags8k02 |
|---|---|
| Clone Library Name | barley_pub |
>HT1_ARATH (Q2MHE4) Serine/threonine-protein kinase HT1 (EC 2.7.11.1) (High| leaf temperature protein 1) Length = 390 Score = 70.5 bits (171), Expect = 3e-12 Identities = 29/71 (40%), Positives = 46/71 (64%) Frame = -1 Query: 590 LLWXLLTGKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDFS 411 +LW L T +P++ TP+QAA V +K RP +P + L L+++CW ++P++RPDFS Sbjct: 275 VLWELTTALLPFQGMTPVQAAFAVAEKNERPPLPASCQPALAHLIKRCWSENPSKRPDFS 334 Query: 410 EILEALKKIAE 378 I+ L+K E Sbjct: 335 NIVAVLEKYDE 345
>M3KSL_DROME (Q95UN8) Mitogen-activated protein kinase kinase kinase (EC| 2.7.11.25) (Mixed lineage kinase) (dMLK) (Protein slipper) Length = 1161 Score = 65.1 bits (157), Expect = 1e-10 Identities = 32/70 (45%), Positives = 40/70 (57%) Frame = -1 Query: 590 LLWXLLTGKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDFS 411 LLW L+TG+ PY+ PL A GV L IPK L++ CWQ DP +RP F Sbjct: 334 LLWELITGETPYKGFDPLSVAYGVAVNTLTLPIPKTCPETWGALMKSCWQTDPHKRPGFK 393 Query: 410 EILEALKKIA 381 EIL+ L+ IA Sbjct: 394 EILKQLESIA 403
>M3K11_HUMAN (Q16584) Mitogen-activated protein kinase kinase kinase 11 (EC| 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline-rich kinase) Length = 847 Score = 62.4 bits (150), Expect = 9e-10 Identities = 30/73 (41%), Positives = 39/73 (53%) Frame = -1 Query: 590 LLWXLLTGKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDFS 411 LLW LLTG++PY L A GV L IP +L+ CW QDP RPDF+ Sbjct: 311 LLWELLTGEVPYRGIDCLAVAYGVAVNKLTLPIPSTCPEPFAQLMADCWAQDPHRRPDFA 370 Query: 410 EILEALKKIAEEV 372 IL+ L+ + +V Sbjct: 371 SILQQLEALEAQV 383
>M3K10_HUMAN (Q02779) Mitogen-activated protein kinase kinase kinase 10 (EC| 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST) Length = 954 Score = 62.0 bits (149), Expect = 1e-09 Identities = 30/71 (42%), Positives = 37/71 (52%) Frame = -1 Query: 590 LLWXLLTGKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDFS 411 LLW LLTG++PY L A GV L IP LL++CW DP RPDF Sbjct: 292 LLWELLTGEVPYREIDALAVAYGVAMNKLTLPIPSTCPEPFARLLEECWDPDPHGRPDFG 351 Query: 410 EILEALKKIAE 378 IL+ L+ I + Sbjct: 352 SILKRLEVIEQ 362
>M3KL4_HUMAN (Q5TCX8) Mitogen-activated protein kinase kinase kinase (EC| 2.7.11.25) (Mixed lineage kinase 4) Length = 1036 Score = 61.6 bits (148), Expect = 2e-09 Identities = 33/76 (43%), Positives = 40/76 (52%) Frame = -1 Query: 590 LLWXLLTGKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDFS 411 LLW LLTG++PY L A GV L IP +L+++CWQQDP RP F+ Sbjct: 333 LLWELLTGEVPYRGIDGLAVAYGVAVNKLTLPIPSTCPEPFAKLMKECWQQDPHIRPSFA 392 Query: 410 EILEALKKIAEEVGDE 363 ILE L I V E Sbjct: 393 LILEQLTAIEGAVMTE 408
>KYK2_DICDI (P18161) Tyrosine-protein kinase 2 (EC 2.7.10.2) (Fragment)| Length = 410 Score = 61.2 bits (147), Expect = 2e-09 Identities = 28/70 (40%), Positives = 43/70 (61%) Frame = -1 Query: 590 LLWXLLTGKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDFS 411 ++W +LTG+IP+ Q + V GLRP IP+ +L LL +CW+ DP +RP F+ Sbjct: 299 VVWEILTGEIPFSDLDGSQRSAQVAYAGLRPPIPEYCDPELKLLLTQCWEADPNDRPPFT 358 Query: 410 EILEALKKIA 381 I+ LK+I+ Sbjct: 359 YIVNKLKEIS 368
>M3K9_HUMAN (P80192) Mitogen-activated protein kinase kinase kinase 9 (EC| 2.7.11.25) (Mixed lineage kinase 1) Length = 1104 Score = 58.5 bits (140), Expect = 1e-08 Identities = 28/71 (39%), Positives = 36/71 (50%) Frame = -1 Query: 590 LLWXLLTGKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDFS 411 LLW LLTG++P+ L A GV L IP +L++ CW DP RP F+ Sbjct: 338 LLWELLTGEVPFRGIDGLAVAYGVAMNKLALPIPSTCPEPFAKLMEDCWNPDPHSRPSFT 397 Query: 410 EILEALKKIAE 378 IL+ L I E Sbjct: 398 NILDQLTTIEE 408
>MLTK_MOUSE (Q9ESL4) Mitogen-activated protein kinase kinase kinase MLT (EC| 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper-and sterile alpha motif kinase ZAK) (Sterile alpha motif- and leucine zipper-containing kinase AZK) ( Length = 802 Score = 58.5 bits (140), Expect = 1e-08 Identities = 26/72 (36%), Positives = 43/72 (59%) Frame = -1 Query: 590 LLWXLLTGKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDFS 411 +LW +LT ++P++ LQ A VV+K R TIP + ELL +CW+ D +RP F Sbjct: 195 VLWEMLTREVPFKGLEGLQVAWLVVEKNERLTIPSSCPRSFAELLHQCWEADAKKRPSFK 254 Query: 410 EILEALKKIAEE 375 +I+ L+ ++ + Sbjct: 255 QIISILESMSND 266
>MLTK_HUMAN (Q9NYL2) Mitogen-activated protein kinase kinase kinase MLT (EC| 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper-and sterile alpha motif-containing kinase) (Sterile alpha motif- and leucine zipper-containing kinase Length = 800 Score = 58.5 bits (140), Expect = 1e-08 Identities = 26/72 (36%), Positives = 43/72 (59%) Frame = -1 Query: 590 LLWXLLTGKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDFS 411 +LW +LT ++P++ LQ A VV+K R TIP + ELL +CW+ D +RP F Sbjct: 195 VLWEMLTREVPFKGLEGLQVAWLVVEKNERLTIPSSCPRSFAELLHQCWEADAKKRPSFK 254 Query: 410 EILEALKKIAEE 375 +I+ L+ ++ + Sbjct: 255 QIISILESMSND 266
>ILK1_HUMAN (Q13418) Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59| kDa serine/threonine-protein kinase) (p59ILK) Length = 452 Score = 57.0 bits (136), Expect = 4e-08 Identities = 25/72 (34%), Positives = 45/72 (62%) Frame = -1 Query: 590 LLWXLLTGKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDFS 411 LLW L+T ++P+ + ++ + V +GLRPTIP + +L++ C +DPA+RP F Sbjct: 381 LLWELVTREVPFADLSNMEIGMKVALEGLRPTIPPGISPHVCKLMKICMNEDPAKRPKFD 440 Query: 410 EILEALKKIAEE 375 I+ L+K+ ++ Sbjct: 441 MIVPILEKMQDK 452
>ILK_MOUSE (O55222) Integrin-linked protein kinase (EC 2.7.11.1)| Length = 452 Score = 56.6 bits (135), Expect = 5e-08 Identities = 24/72 (33%), Positives = 45/72 (62%) Frame = -1 Query: 590 LLWXLLTGKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDFS 411 LLW L+T ++P+ + ++ + V +GLRPT+P + +L++ C +DPA+RP F Sbjct: 381 LLWELVTREVPFADLSNMEIGMKVALEGLRPTVPPGISPHVCKLMKICMNEDPAKRPKFD 440 Query: 410 EILEALKKIAEE 375 I+ L+K+ ++ Sbjct: 441 MIVPILEKMQDK 452
>YR831_MIMIV (Q7T6Y2) Putative serine/threonine-protein kinase/receptor R831| precursor (EC 2.7.11.1) Length = 1624 Score = 54.7 bits (130), Expect = 2e-07 Identities = 28/73 (38%), Positives = 40/73 (54%), Gaps = 4/73 (5%) Frame = -1 Query: 590 LLWXLLTGKIPYEYXTPLQAAVGVVQKGLRPTIPKNA----HAKLTELLQKCWQQDPAER 423 +LW LLT + PY+ TP AV V++ G+RP I A + +L+++CW D R Sbjct: 976 ILWELLTREQPYKGMTPAAIAVSVIRDGMRPPISDEAVTAHSIEYIDLIKQCWHSDTIIR 1035 Query: 422 PDFSEILEALKKI 384 P F EI+ L I Sbjct: 1036 PTFLEIMTRLSNI 1048 Score = 49.7 bits (117), Expect = 6e-06 Identities = 21/72 (29%), Positives = 43/72 (59%) Frame = -1 Query: 590 LLWXLLTGKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDFS 411 ++W +LTGK P+ ++ ++ +++ G RP IP + + +L++KCW +RP + Sbjct: 1549 VMWEVLTGKEPFAECNFMKVSLDILEGG-RPIIPSDCPHEFAKLIKKCWHAKAHKRPTMT 1607 Query: 410 EILEALKKIAEE 375 E+++ L I E+ Sbjct: 1608 EVVQQLMLITEQ 1619
>ILK2_HUMAN (P57043) Integrin-linked protein kinase 2 (EC 2.7.11.1) (ILK-2)| Length = 452 Score = 53.9 bits (128), Expect = 3e-07 Identities = 24/72 (33%), Positives = 44/72 (61%) Frame = -1 Query: 590 LLWXLLTGKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDFS 411 LLW L+T ++P+ + ++ + V +GLRPTIP + +L++ C +DPA+R F Sbjct: 381 LLWELVTREVPFADLSNMEIGMKVALEGLRPTIPPGISPHVCKLMKICMNEDPAKRSKFD 440 Query: 410 EILEALKKIAEE 375 I+ L+K+ ++ Sbjct: 441 MIVPILEKMQDK 452
>FGFR4_RAT (Q498D6) Fibroblast growth factor receptor 4 precursor (EC| 2.7.10.1) (FGFR-4) Length = 800 Score = 52.4 bits (124), Expect = 1e-06 Identities = 26/78 (33%), Positives = 46/78 (58%), Gaps = 1/78 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW + T G PY P++ ++++G R P N ++L L+++CW P++RP F Sbjct: 676 LLWEIFTLGGSPYP-GIPVEELFSLLREGHRMERPPNCPSELYGLMRECWHAAPSQRPTF 734 Query: 413 SEILEALKKIAEEVGDEH 360 +++EAL K+ V +E+ Sbjct: 735 KQLVEALDKVLLAVSEEY 752
>FGFR4_MOUSE (Q03142) Fibroblast growth factor receptor 4 precursor (EC| 2.7.10.1) (FGFR-4) (Protein-tyrosine kinase receptor MPK-11) Length = 799 Score = 52.4 bits (124), Expect = 1e-06 Identities = 26/78 (33%), Positives = 46/78 (58%), Gaps = 1/78 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW + T G PY P++ ++++G R P N ++L L+++CW P++RP F Sbjct: 675 LLWEIFTLGGSPYP-GIPVEELFSLLREGHRMERPPNCPSELYGLMRECWHAAPSQRPTF 733 Query: 413 SEILEALKKIAEEVGDEH 360 +++EAL K+ V +E+ Sbjct: 734 KQLVEALDKVLLAVSEEY 751
>TXK_HUMAN (P42681) Tyrosine-protein kinase TXK (EC 2.7.10.2)| Length = 527 Score = 51.6 bits (122), Expect = 2e-06 Identities = 27/72 (37%), Positives = 42/72 (58%), Gaps = 1/72 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 L+W + T GK+P+E + LQ V + +G R P A + E++ CW + P RP F Sbjct: 455 LMWEVFTEGKMPFENKSNLQV-VEAISEGFRLYRPHLAPMSIYEVMYSCWHEKPEGRPTF 513 Query: 413 SEILEALKKIAE 378 +E+L A+ +IAE Sbjct: 514 AELLRAVTEIAE 525
>TNI3K_RAT (Q7TQP6) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 834 Score = 51.2 bits (121), Expect = 2e-06 Identities = 24/67 (35%), Positives = 38/67 (56%) Frame = -1 Query: 587 LWXLLTGKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDFSE 408 LW LLTG+IP+ + P AA + +RP I + ++ LL + W P RP+FSE Sbjct: 654 LWELLTGEIPFAHLKPAAAAADMAYHHIRPPIGYSIPKPISSLLIRGWNACPEGRPEFSE 713 Query: 407 ILEALKK 387 ++ L++ Sbjct: 714 VVSKLEE 720
>ILK_CAVPO (P57044) Integrin-linked protein kinase (EC 2.7.11.1)| (Beta-integrin-linked kinase) Length = 451 Score = 50.8 bits (120), Expect = 3e-06 Identities = 24/72 (33%), Positives = 44/72 (61%) Frame = -1 Query: 590 LLWXLLTGKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDFS 411 LLW L+T ++P+ + ++ + V +G RPTIP + +L++ C +DPA+RP F Sbjct: 381 LLWELVTREVPFADLSNMEIGMKVALEG-RPTIPPGISPHVCKLMKICMNEDPAKRPKFD 439 Query: 410 EILEALKKIAEE 375 I+ L+K+ ++ Sbjct: 440 MIVPILEKMQDK 451
>CSK_CHICK (P41239) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| Length = 450 Score = 50.8 bits (120), Expect = 3e-06 Identities = 27/73 (36%), Positives = 41/73 (56%), Gaps = 1/73 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW + + G++PY PL+ V V+KG + P A + E+++KCW DP RP F Sbjct: 375 LLWEIYSFGRVPYP-RIPLKDVVPRVEKGYKMDPPDGCPAIVYEVMKKCWTLDPGHRPSF 433 Query: 413 SEILEALKKIAEE 375 ++ E L I E+ Sbjct: 434 HQLREQLVHIKEK 446
>TXK_MOUSE (P42682) Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18)| (Resting lymphocyte kinase) Length = 527 Score = 50.1 bits (118), Expect = 5e-06 Identities = 26/72 (36%), Positives = 41/72 (56%), Gaps = 1/72 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 L+W + T GK+P+E + LQ V + +G R P A + ++ CW + P RP F Sbjct: 455 LMWEVFTEGKMPFENKSNLQV-VEAISQGFRLYRPHLAPMTIYRVMYSCWHESPKGRPTF 513 Query: 413 SEILEALKKIAE 378 +E+L+ L +IAE Sbjct: 514 AELLQVLTEIAE 525
>TNI3K_MOUSE (Q5GIG6) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 833 Score = 50.1 bits (118), Expect = 5e-06 Identities = 23/67 (34%), Positives = 37/67 (55%) Frame = -1 Query: 587 LWXLLTGKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDFSE 408 LW LL G+IP+ + P AA + +RP I + ++ LL + W P RP+FSE Sbjct: 653 LWELLIGEIPFAHLKPAAAAADMAYHHIRPPIGYSIPKPISSLLMRGWNACPEGRPEFSE 712 Query: 407 ILEALKK 387 ++ L++ Sbjct: 713 VVRKLEE 719
>TNI3K_HUMAN (Q59H18) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 936 Score = 49.7 bits (117), Expect = 6e-06 Identities = 23/67 (34%), Positives = 38/67 (56%) Frame = -1 Query: 587 LWXLLTGKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDFSE 408 LW +LTG+IP+ + P AA + +RP I + ++ LL + W P RP+FSE Sbjct: 756 LWEILTGEIPFAHLKPAAAAADMAYHHIRPPIGYSIPKPISSLLIRGWNACPEGRPEFSE 815 Query: 407 ILEALKK 387 ++ L++ Sbjct: 816 VVMKLEE 822
>FGFR4_HUMAN (P22455) Fibroblast growth factor receptor 4 precursor (EC| 2.7.10.1) (FGFR-4) (CD334 antigen) Length = 802 Score = 49.7 bits (117), Expect = 6e-06 Identities = 25/78 (32%), Positives = 45/78 (57%), Gaps = 1/78 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW + T G PY P++ ++++G R P + +L L+++CW P++RP F Sbjct: 678 LLWEIFTLGGSPYP-GIPVEELFSLLREGHRMDRPPHCPPELYGLMRECWHAAPSQRPTF 736 Query: 413 SEILEALKKIAEEVGDEH 360 +++EAL K+ V +E+ Sbjct: 737 KQLVEALDKVLLAVSEEY 754
>PHY1_CERPU (P25848) Light-sensor Protein kinase [Includes: Phytochrome; Protein| kinase (EC 2.7.11.1)] Length = 1307 Score = 49.3 bits (116), Expect = 8e-06 Identities = 22/65 (33%), Positives = 36/65 (55%) Frame = -1 Query: 584 WXLLTGKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDFSEI 405 + +LTG +P+ +V +G+RP +P + +L L+ CW QDP +RP F+ I Sbjct: 1219 YEVLTGDVPFPEEKNPNNVKRMVLEGVRPDLPAHCPIELKALITDCWNQDPLKRPSFAVI 1278 Query: 404 LEALK 390 + LK Sbjct: 1279 CQKLK 1283
>KYK1_DICDI (P18160) Non-receptor tyrosine kinase spore lysis A (EC 2.7.10.2)| (Tyrosine-protein kinase 1) Length = 1584 Score = 49.3 bits (116), Expect = 8e-06 Identities = 23/72 (31%), Positives = 39/72 (54%) Frame = -1 Query: 590 LLWXLLTGKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDFS 411 +L+ LLT P + P++ A + RP IP +K E+L +CW +P RP F Sbjct: 1494 VLFELLTSDEPQQDMKPMKMAHLAAYESYRPPIPLTTSSKWKEILTQCWDSNPDSRPTFK 1553 Query: 410 EILEALKKIAEE 375 +I+ LK++ ++ Sbjct: 1554 QIIVHLKEMEDQ 1565
>ABL2_HUMAN (P42684) Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine| leukemia viral oncogene homolog 2) (Tyrosine kinase ARG) Length = 1182 Score = 48.9 bits (115), Expect = 1e-05 Identities = 29/83 (34%), Positives = 44/83 (53%), Gaps = 7/83 (8%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW + T G PY L +++KG R P+ K+ EL++ CW+ PA+RP F Sbjct: 474 LLWEIATYGMSPYP-GIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWKWSPADRPSF 532 Query: 413 SEILEALK------KIAEEVGDE 363 +E +A + I+EEV +E Sbjct: 533 AETHQAFETMFHDSSISEEVAEE 555
>ITK_MOUSE (Q03526) Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2)| (T-cell-specific kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK) Length = 625 Score = 48.9 bits (115), Expect = 1e-05 Identities = 25/72 (34%), Positives = 42/72 (58%), Gaps = 1/72 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 L+W + + GKIPYE + + V + G R P+ A + +++ CW++ P +RP F Sbjct: 552 LMWEVFSEGKIPYENRSNSEV-VEDISTGFRLYKPRLASCHVYQIMNHCWKEKPEDRPPF 610 Query: 413 SEILEALKKIAE 378 S++L L +IAE Sbjct: 611 SQLLSQLAEIAE 622
>M3K7_MOUSE (Q62073) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1) Length = 579 Score = 48.5 bits (114), Expect = 1e-05 Identities = 21/67 (31%), Positives = 37/67 (55%), Gaps = 1/67 (1%) Frame = -1 Query: 590 LLWXLLTGKIPY-EYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 +LW ++T + P+ E P + V G RP + KN + L+ +CW +DP++RP Sbjct: 218 ILWEVITRRKPFDEIGGPAFRIMWAVHNGTRPPLIKNLPKPIESLMTRCWSKDPSQRPSM 277 Query: 413 SEILEAL 393 EI++ + Sbjct: 278 EEIVKIM 284
>M3K7_HUMAN (O43318) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1) Length = 606 Score = 48.5 bits (114), Expect = 1e-05 Identities = 21/67 (31%), Positives = 37/67 (55%), Gaps = 1/67 (1%) Frame = -1 Query: 590 LLWXLLTGKIPY-EYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 +LW ++T + P+ E P + V G RP + KN + L+ +CW +DP++RP Sbjct: 218 ILWEVITRRKPFDEIGGPAFRIMWAVHNGTRPPLIKNLPKPIESLMTRCWSKDPSQRPSM 277 Query: 413 SEILEAL 393 EI++ + Sbjct: 278 EEIVKIM 284
>EPHAA_HUMAN (Q5JZY3) Ephrin type-A receptor 10 precursor (EC 2.7.10.1)| Length = 1008 Score = 48.1 bits (113), Expect = 2e-05 Identities = 25/73 (34%), Positives = 40/73 (54%), Gaps = 1/73 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 ++W ++ G+ PY + Q + V+ G R P+N L L+ CWQ+DP ERP F Sbjct: 835 IMWEVMAFGERPY-WDMSGQDVIKAVEDGFRLPPPRNCPNLLHRLMLDCWQKDPGERPRF 893 Query: 413 SEILEALKKIAEE 375 S+I L K+ ++ Sbjct: 894 SQIHSILSKMVQD 906
>CTR1_ARATH (Q05609) Serine/threonine-protein kinase CTR1 (EC 2.7.11.1)| Length = 821 Score = 48.1 bits (113), Expect = 2e-05 Identities = 21/69 (30%), Positives = 38/69 (55%) Frame = -1 Query: 590 LLWXLLTGKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDFS 411 +LW L T + P+ P Q V K R IP+N + ++ +++ CW +P +RP F+ Sbjct: 740 ILWELATLQQPWGNLNPAQVVAAVGFKCKRLEIPRNLNPQVAAIIEGCWTNEPWKRPSFA 799 Query: 410 EILEALKKI 384 I++ L+ + Sbjct: 800 TIMDLLRPL 808
>ITK_HUMAN (Q08881) Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2)| (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT) Length = 620 Score = 47.4 bits (111), Expect = 3e-05 Identities = 25/72 (34%), Positives = 41/72 (56%), Gaps = 1/72 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 L+W + + GKIPYE + + V + G R P+ A + +++ CW++ P +RP F Sbjct: 547 LMWEVFSEGKIPYENRSNSEV-VEDISTGFRLYKPRLASTHVYQIMNHCWKERPEDRPAF 605 Query: 413 SEILEALKKIAE 378 S +L L +IAE Sbjct: 606 SRLLRQLAEIAE 617
>ABL_MLVAB (P00521) Tyrosine-protein kinase transforming protein Abl (EC| 2.7.10.2) (V-abl) Length = 746 Score = 47.4 bits (111), Expect = 3e-05 Identities = 27/79 (34%), Positives = 44/79 (55%), Gaps = 3/79 (3%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW + T G PY L +++K R P+ K+ EL++ CWQ +P++RP F Sbjct: 314 LLWEIATYGMSPYP-GIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSF 372 Query: 413 SEILEALKKIAEE--VGDE 363 +EI +A + + +E + DE Sbjct: 373 AEIHQAFETMFQESSISDE 391
>ABL1_HUMAN (P00519) Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2)| (p150) (c-ABL) (Abelson murine leukemia viral oncogene homolog 1) Length = 1130 Score = 47.4 bits (111), Expect = 3e-05 Identities = 27/79 (34%), Positives = 44/79 (55%), Gaps = 3/79 (3%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW + T G PY L +++K R P+ K+ EL++ CWQ +P++RP F Sbjct: 428 LLWEIATYGMSPYP-GIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSF 486 Query: 413 SEILEALKKIAEE--VGDE 363 +EI +A + + +E + DE Sbjct: 487 AEIHQAFETMFQESSISDE 505
>M3K12_RAT (Q63796) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 888 Score = 47.4 bits (111), Expect = 3e-05 Identities = 23/63 (36%), Positives = 32/63 (50%) Frame = -1 Query: 590 LLWXLLTGKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDFS 411 +LW LLTG+IPY+ GV L +P + LL++CW + P RP F Sbjct: 332 VLWELLTGEIPYKDVDSSAIIWGVGSNSLHLPVPSSCPDGFKILLRQCWNRKPRNRPSFR 391 Query: 410 EIL 402 +IL Sbjct: 392 QIL 394
>PTK7_CHICK (Q91048) Tyrosine-protein kinase-like 7 precursor (Kinase-like| protein) Length = 1051 Score = 47.4 bits (111), Expect = 3e-05 Identities = 22/67 (32%), Positives = 37/67 (55%), Gaps = 1/67 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 L+W + T G++PY + G+ + P+ ++LT+L+Q+CW P +RP F Sbjct: 976 LMWEVFTQGEMPYAPLADDEVLAGLKSGKTKLPQPEGCPSRLTKLMQRCWAPSPKDRPSF 1035 Query: 413 SEILEAL 393 SE+ AL Sbjct: 1036 SELAAAL 1042
>TEC_HUMAN (P42680) Tyrosine-protein kinase Tec (EC 2.7.10.2)| Length = 631 Score = 47.4 bits (111), Expect = 3e-05 Identities = 24/72 (33%), Positives = 42/72 (58%), Gaps = 1/72 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 L+W + T G++P+E T + V +V +G R PK A + E++ +CWQ+ P RP F Sbjct: 554 LMWEVFTEGRMPFEKYTNYEV-VTMVTRGHRLYQPKLASNYVYEVMLRCWQEKPEGRPSF 612 Query: 413 SEILEALKKIAE 378 ++L + ++ E Sbjct: 613 EDLLRTIDELVE 624
>ABL1_MOUSE (P00520) Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2)| (p150) (c-ABL) (Abelson murine leukemia viral oncogene homolog 1) Length = 1123 Score = 47.4 bits (111), Expect = 3e-05 Identities = 27/79 (34%), Positives = 44/79 (55%), Gaps = 3/79 (3%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW + T G PY L +++K R P+ K+ EL++ CWQ +P++RP F Sbjct: 428 LLWEIATYGMSPYP-GIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSF 486 Query: 413 SEILEALKKIAEE--VGDE 363 +EI +A + + +E + DE Sbjct: 487 AEIHQAFETMFQESSISDE 505
>M3K12_MOUSE (Q60700) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 888 Score = 47.0 bits (110), Expect = 4e-05 Identities = 23/63 (36%), Positives = 31/63 (49%) Frame = -1 Query: 590 LLWXLLTGKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDFS 411 +LW LLTG+IPY+ GV L +P + LL++CW P RP F Sbjct: 332 VLWELLTGEIPYKDVDSSAIIWGVGSNSLHLPVPSSCPDGFKILLRQCWNSKPRNRPSFR 391 Query: 410 EIL 402 +IL Sbjct: 392 QIL 394
>M3K12_HUMAN (Q12852) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 859 Score = 47.0 bits (110), Expect = 4e-05 Identities = 23/63 (36%), Positives = 31/63 (49%) Frame = -1 Query: 590 LLWXLLTGKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDFS 411 +LW LLTG+IPY+ GV L +P + LL++CW P RP F Sbjct: 299 VLWELLTGEIPYKDVDSSAIIWGVGSNSLHLPVPSSCPDGFKILLRQCWNSKPRNRPSFR 358 Query: 410 EIL 402 +IL Sbjct: 359 QIL 361
>RON_HUMAN (Q04912) Macrophage-stimulating protein receptor precursor (EC| 2.7.10.1) (MSP receptor) (p185-Ron) (CDw136 antigen) [Contains: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain] Length = 1400 Score = 46.2 bits (108), Expect = 7e-05 Identities = 26/78 (33%), Positives = 41/78 (52%), Gaps = 1/78 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW LLT G PY + P + Q G R P+ L +++Q+CW+ DPA RP F Sbjct: 1276 LLWELLTRGAPPYRHIDPFDLTHFLAQ-GRRLPQPEYCPDSLYQVMQQCWEADPAVRPTF 1334 Query: 413 SEILEALKKIAEEVGDEH 360 ++ +++I + +H Sbjct: 1335 RVLVGEVEQIVSALLGDH 1352
>TEC_MOUSE (P24604) Tyrosine-protein kinase Tec (EC 2.7.10.2)| Length = 630 Score = 46.2 bits (108), Expect = 7e-05 Identities = 24/72 (33%), Positives = 41/72 (56%), Gaps = 1/72 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 L+W + T G++P+E T + V +V +G R PK A L E++ +CWQ+ P RP Sbjct: 553 LMWEIFTEGRMPFEKNTNYEV-VTMVTRGHRLHRPKLATKYLYEVMLRCWQERPEGRPSL 611 Query: 413 SEILEALKKIAE 378 ++L + ++ E Sbjct: 612 EDLLRTIDELVE 623
>KIT_BOVIN (P43481) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 977 Score = 45.8 bits (107), Expect = 9e-05 Identities = 21/72 (29%), Positives = 40/72 (55%), Gaps = 1/72 (1%) Frame = -1 Query: 587 LWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDFS 411 LW L + G PY ++++G R P++A A++ ++++ CW DP +RP F Sbjct: 860 LWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRPTFK 919 Query: 410 EILEALKKIAEE 375 +I++ ++K E Sbjct: 920 QIVQLIEKQISE 931
>KIT_HUMAN (P10721) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen) Length = 976 Score = 45.8 bits (107), Expect = 9e-05 Identities = 21/72 (29%), Positives = 40/72 (55%), Gaps = 1/72 (1%) Frame = -1 Query: 587 LWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDFS 411 LW L + G PY ++++G R P++A A++ ++++ CW DP +RP F Sbjct: 859 LWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRPTFK 918 Query: 410 EILEALKKIAEE 375 +I++ ++K E Sbjct: 919 QIVQLIEKQISE 930
>KIT_CAPHI (Q28317) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 978 Score = 45.8 bits (107), Expect = 9e-05 Identities = 21/72 (29%), Positives = 40/72 (55%), Gaps = 1/72 (1%) Frame = -1 Query: 587 LWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDFS 411 LW L + G PY ++++G R P++A A++ ++++ CW DP +RP F Sbjct: 861 LWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRPTFK 920 Query: 410 EILEALKKIAEE 375 +I++ ++K E Sbjct: 921 QIVQLIEKQISE 932
>CSK_HUMAN (P41240) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| (Protein-tyrosine kinase CYL) Length = 450 Score = 45.4 bits (106), Expect = 1e-04 Identities = 24/70 (34%), Positives = 38/70 (54%), Gaps = 1/70 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW + + G++PY PL+ V V+KG + P + E+++ CW D A RP F Sbjct: 375 LLWEIYSFGRVPYP-RIPLKDVVPRVEKGYKMDAPDGCPPAVYEVMKNCWHLDAAMRPSF 433 Query: 413 SEILEALKKI 384 ++ E L+ I Sbjct: 434 LQLREQLEHI 443
>KIT_FSVHZ (P04048) Tyrosine-protein kinase transforming protein kit (EC| 2.7.10.1) Length = 370 Score = 45.4 bits (106), Expect = 1e-04 Identities = 20/68 (29%), Positives = 39/68 (57%), Gaps = 1/68 (1%) Frame = -1 Query: 587 LWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDFS 411 LW L + G PY ++++G R P++A A++ ++++ CW DP +RP F Sbjct: 297 LWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRPTFK 356 Query: 410 EILEALKK 387 +I++ ++K Sbjct: 357 QIVQLIEK 364
>RON_MOUSE (Q62190) Macrophage-stimulating protein receptor precursor (EC| 2.7.10.1) (MSP receptor) (p185-Ron) (Stem cell-derived tyrosine kinase) (CDw136 antigen) [Contains: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating prote Length = 1378 Score = 45.4 bits (106), Expect = 1e-04 Identities = 28/79 (35%), Positives = 42/79 (53%), Gaps = 2/79 (2%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW LLT G PY + P + + Q G R P+ L ++ +CW+ DPA RP F Sbjct: 1253 LLWELLTRGAPPYPHIDPFDLSHFLAQ-GRRLPQPEYCPDSLYHVMLRCWEADPAARPTF 1311 Query: 413 -SEILEALKKIAEEVGDEH 360 + +LE + +A +GD + Sbjct: 1312 RALVLEVKQVVASLLGDHY 1330
>KIT_CANFA (O97799) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 975 Score = 45.4 bits (106), Expect = 1e-04 Identities = 20/68 (29%), Positives = 39/68 (57%), Gaps = 1/68 (1%) Frame = -1 Query: 587 LWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDFS 411 LW L + G PY ++++G R P++A A++ ++++ CW DP +RP F Sbjct: 858 LWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRPTFK 917 Query: 410 EILEALKK 387 +I++ ++K Sbjct: 918 QIVQLIEK 925
>KIT_FELCA (Q28889) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 978 Score = 45.4 bits (106), Expect = 1e-04 Identities = 20/68 (29%), Positives = 39/68 (57%), Gaps = 1/68 (1%) Frame = -1 Query: 587 LWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDFS 411 LW L + G PY ++++G R P++A A++ ++++ CW DP +RP F Sbjct: 860 LWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRPTFK 919 Query: 410 EILEALKK 387 +I++ ++K Sbjct: 920 QIVQLIEK 927
>TIE2_BRARE (O73791) Tyrosine-protein kinase receptor Tie-2 precursor (EC| 2.7.10.1) Length = 1116 Score = 45.4 bits (106), Expect = 1e-04 Identities = 27/73 (36%), Positives = 42/73 (57%), Gaps = 1/73 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW +++ G PY T + + G R P N ++ EL+Q+CW++ P ERP F Sbjct: 1019 LLWEVVSLGGTPYCGMTCAEL-YEKLPLGFRLEKPLNCDDEVYELMQQCWREKPFERPSF 1077 Query: 413 SEILEALKKIAEE 375 S+IL +L ++ EE Sbjct: 1078 SQILLSLGRMLEE 1090
>CAD96_DROME (Q9VBW3) Tyrosine kinase receptor Cad96Ca precursor (EC 2.7.10.1)| (Cadherin 96Ca) (Tyrosine kinase receptor HD-14) Length = 773 Score = 45.4 bits (106), Expect = 1e-04 Identities = 26/73 (35%), Positives = 41/73 (56%), Gaps = 4/73 (5%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQK---GLRPTIPKNAHAKLTELLQKCWQQDPAER 423 L+W ++T G PY P +A V++K G R P++ +L ++ CW DP ER Sbjct: 676 LMWEIVTLGSTPY----PGISAADVMRKVRDGYRLEKPEHCRRELYNIMYYCWSHDPQER 731 Query: 422 PDFSEILEALKKI 384 P F+EI++ L K+ Sbjct: 732 PLFAEIIQMLDKL 744
>BTK_CHICK (Q8JH64) Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton's| tyrosine kinase) Length = 657 Score = 45.4 bits (106), Expect = 1e-04 Identities = 24/73 (32%), Positives = 40/73 (54%), Gaps = 1/73 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 L+W + + GK+PYE + V+Q GLR P+ A ++ ++ CW + ERP F Sbjct: 584 LMWEVYSLGKMPYERFNNSETTEHVIQ-GLRLYRPQQASERVYAIMYSCWHEKAEERPTF 642 Query: 413 SEILEALKKIAEE 375 S +L ++ I +E Sbjct: 643 SALLGSIVDITDE 655
>PGFRB_MOUSE (P05622) Beta platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-beta) Length = 1098 Score = 45.1 bits (105), Expect = 2e-04 Identities = 22/73 (30%), Positives = 39/73 (53%), Gaps = 1/73 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW + T G PY +++G R P +A ++ E++QKCW++ RP F Sbjct: 891 LLWEIFTLGGTPYPELPMNDQFYNAIKRGYRMAQPAHASDEIYEIMQKCWEEKFETRPPF 950 Query: 413 SEILEALKKIAEE 375 S+++ L+++ E Sbjct: 951 SQLVLLLERLLGE 963
>PGFRB_CANFA (Q6QNF3) Beta platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-beta) Length = 1103 Score = 45.1 bits (105), Expect = 2e-04 Identities = 22/73 (30%), Positives = 40/73 (54%), Gaps = 1/73 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW + T G PY + +++G R P +A ++ E++QKCW++ RP F Sbjct: 892 LLWEIFTLGGTPYPELPMNEQFYNAIKRGYRMAQPAHASDEIYEIMQKCWEEKFEIRPPF 951 Query: 413 SEILEALKKIAEE 375 S+++ L+++ E Sbjct: 952 SQLVLLLERLLGE 964
>EPHA7_MOUSE (Q61772) Ephrin type-A receptor 7 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Embryonic brain kinase) (EBK) (Developmental kinase 1) (MDK-1) Length = 998 Score = 45.1 bits (105), Expect = 2e-04 Identities = 23/70 (32%), Positives = 41/70 (58%), Gaps = 1/70 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 ++W +++ G+ PY + Q + +++G R P + A L +L+ CWQ+D AERP F Sbjct: 825 VMWEVMSYGERPY-WDMSNQDVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKDRAERPKF 883 Query: 413 SEILEALKKI 384 +I+ L K+ Sbjct: 884 EQIVGILDKM 893
>KIT_MOUSE (P05532) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 975 Score = 45.1 bits (105), Expect = 2e-04 Identities = 19/68 (27%), Positives = 39/68 (57%), Gaps = 1/68 (1%) Frame = -1 Query: 587 LWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDFS 411 LW L + G PY ++++G R P++A A++ ++++ CW DP +RP F Sbjct: 857 LWELFSLGSSPYPGMPVDSKFYKMIKEGFRMVSPEHAPAEMYDVMKTCWDADPLKRPTFK 916 Query: 410 EILEALKK 387 ++++ ++K Sbjct: 917 QVVQLIEK 924
>VGFR1_RAT (P53767) Vascular endothelial growth factor receptor 1 precursor (EC| 2.7.10.1) (VEGFR-1) (Tyrosine-protein kinase receptor FLT) (FLT-1) Length = 1336 Score = 45.1 bits (105), Expect = 2e-04 Identities = 24/81 (29%), Positives = 44/81 (54%), Gaps = 1/81 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW + + G PY + +++G+R P+ A ++ +++ CW +DP ERP F Sbjct: 1088 LLWEIFSLGGSPYPGVQMDEDFCSRLKEGMRMRTPEYATPEIYQIMLDCWHKDPKERPRF 1147 Query: 413 SEILEALKKIAEEVGDEHDGK 351 +E++E L + + + DGK Sbjct: 1148 AELVEKLGDLL-QANVQQDGK 1167
>FAK1_HUMAN (Q05397) Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK)| (Protein-tyrosine kinase 2) Length = 1052 Score = 45.1 bits (105), Expect = 2e-04 Identities = 22/71 (30%), Positives = 33/71 (46%) Frame = -1 Query: 587 LWXLLTGKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDFSE 408 +W +L + +G ++ G R +P N L L+ KCW DP+ RP F+E Sbjct: 612 MWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTE 671 Query: 407 ILEALKKIAEE 375 + L I EE Sbjct: 672 LKAQLSTILEE 682
>PGFRB_HUMAN (P09619) Beta platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-beta) (CD140b antigen) Length = 1106 Score = 45.1 bits (105), Expect = 2e-04 Identities = 22/73 (30%), Positives = 40/73 (54%), Gaps = 1/73 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW + T G PY + +++G R P +A ++ E++QKCW++ RP F Sbjct: 892 LLWEIFTLGGTPYPELPMNEQFYNAIKRGYRMAQPAHASDEIYEIMQKCWEEKFEIRPPF 951 Query: 413 SEILEALKKIAEE 375 S+++ L+++ E Sbjct: 952 SQLVLLLERLLGE 964
>FAK1_MOUSE (P34152) Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK)| Length = 1090 Score = 45.1 bits (105), Expect = 2e-04 Identities = 22/71 (30%), Positives = 33/71 (46%) Frame = -1 Query: 587 LWXLLTGKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDFSE 408 +W +L + +G ++ G R +P N L L+ KCW DP+ RP F+E Sbjct: 650 MWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTE 709 Query: 407 ILEALKKIAEE 375 + L I EE Sbjct: 710 LKAQLSTILEE 720
>MATK_MOUSE (P41242) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK) Length = 505 Score = 45.1 bits (105), Expect = 2e-04 Identities = 25/75 (33%), Positives = 38/75 (50%), Gaps = 1/75 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW + + G+ PY + L+ V+KG R P + L+ CW+ +PA RP F Sbjct: 411 LLWEVFSYGRAPYPKMS-LKEVSEAVEKGYRMEPPDGCPGSVHTLMGSCWEAEPARRPPF 469 Query: 413 SEILEALKKIAEEVG 369 +I+E L + VG Sbjct: 470 RKIVEKLGRELRSVG 484
>FAK1_RAT (O35346) Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK)| Length = 1055 Score = 45.1 bits (105), Expect = 2e-04 Identities = 22/71 (30%), Positives = 33/71 (46%) Frame = -1 Query: 587 LWXLLTGKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDFSE 408 +W +L + +G ++ G R +P N L L+ KCW DP+ RP F+E Sbjct: 612 MWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTE 671 Query: 407 ILEALKKIAEE 375 + L I EE Sbjct: 672 LKAQLSTILEE 682
>PGFRB_RAT (Q05030) Beta platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-beta) Length = 1097 Score = 45.1 bits (105), Expect = 2e-04 Identities = 22/73 (30%), Positives = 39/73 (53%), Gaps = 1/73 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW + T G PY +++G R P +A ++ E++QKCW++ RP F Sbjct: 891 LLWEIFTLGGTPYPELPMNDQFYNAIKRGYRMAQPAHASDEIYEIMQKCWEEKFETRPPF 950 Query: 413 SEILEALKKIAEE 375 S+++ L+++ E Sbjct: 951 SQLVLLLERLLGE 963
>EPHA3_RAT (O08680) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor REK4) (TYRO-4) Length = 984 Score = 45.1 bits (105), Expect = 2e-04 Identities = 24/75 (32%), Positives = 40/75 (53%), Gaps = 1/75 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 +LW +++ G+ PY + Q + V +G R +P + A L +L+ CWQ+D RP F Sbjct: 814 VLWEVMSYGERPY-WEMSNQDVIKAVDEGYRLPLPMDCPAALYQLMLDCWQKDRNNRPKF 872 Query: 413 SEILEALKKIAEEVG 369 +I+ L K+ G Sbjct: 873 EQIVSILDKLIRNPG 887
>VGFR1_MOUSE (P35969) Vascular endothelial growth factor receptor 1 precursor (EC| 2.7.10.1) (VEGFR-1) (Tyrosine-protein kinase receptor FLT) (FLT-1) (Embryonic receptor kinase 2) Length = 1333 Score = 45.1 bits (105), Expect = 2e-04 Identities = 24/81 (29%), Positives = 44/81 (54%), Gaps = 1/81 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW + + G PY + +++G+R P+ A ++ +++ CW +DP ERP F Sbjct: 1088 LLWEIFSLGGSPYPGVQMDEDFCSRLKEGMRMRTPEYATPEIYQIMLDCWHKDPKERPRF 1147 Query: 413 SEILEALKKIAEEVGDEHDGK 351 +E++E L + + + DGK Sbjct: 1148 AELVEKLGDLL-QANVQQDGK 1167
>FAK1_CHICK (Q00944) Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK)| Length = 1053 Score = 45.1 bits (105), Expect = 2e-04 Identities = 22/71 (30%), Positives = 33/71 (46%) Frame = -1 Query: 587 LWXLLTGKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDFSE 408 +W +L + +G ++ G R +P N L L+ KCW DP+ RP F+E Sbjct: 612 MWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTE 671 Query: 407 ILEALKKIAEE 375 + L I EE Sbjct: 672 LKAQLSTILEE 682
>EPA4A_BRARE (O13148) Ephrin type-A receptor 4a (EC 2.7.10.1) (Tyrosine-protein| kinase receptor ZEK2) (EPH-like kinase 2) (Fragment) Length = 292 Score = 44.7 bits (104), Expect = 2e-04 Identities = 22/70 (31%), Positives = 41/70 (58%), Gaps = 1/70 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 ++W +++ G+ PY + Q + +++G R P + L +L+ CWQ++ AERP F Sbjct: 196 VMWEVMSYGERPY-WDMSNQDVIKAIEEGYRLPPPMDCPVSLHQLMLDCWQKERAERPKF 254 Query: 413 SEILEALKKI 384 S+I+ L K+ Sbjct: 255 SQIVNMLDKL 264
>TIE2_BOVIN (Q06807) Angiopoietin-1 receptor precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor TIE-2) (CD202b antigen) Length = 1125 Score = 44.7 bits (104), Expect = 2e-04 Identities = 25/73 (34%), Positives = 43/73 (58%), Gaps = 1/73 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW +++ G PY T + + Q G R P N ++ +L+++CW++ P ERP F Sbjct: 1028 LLWEIVSLGGTPYCGMTCAELYEKLPQ-GYRLEKPLNCDDEVYDLMRQCWREKPYERPSF 1086 Query: 413 SEILEALKKIAEE 375 ++IL +L ++ EE Sbjct: 1087 AQILVSLNRMLEE 1099
>FAK1_XENLA (Q91738) Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK)| Length = 1068 Score = 44.7 bits (104), Expect = 2e-04 Identities = 20/51 (39%), Positives = 28/51 (54%) Frame = -1 Query: 527 VGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDFSEILEALKKIAEE 375 +G ++ G R +P N L L+ KCW DP+ RP F+E+ L I EE Sbjct: 645 IGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEE 695
>TIE2_HUMAN (Q02763) Angiopoietin-1 receptor precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen) Length = 1124 Score = 44.7 bits (104), Expect = 2e-04 Identities = 25/73 (34%), Positives = 43/73 (58%), Gaps = 1/73 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW +++ G PY T + + Q G R P N ++ +L+++CW++ P ERP F Sbjct: 1027 LLWEIVSLGGTPYCGMTCAELYEKLPQ-GYRLEKPLNCDDEVYDLMRQCWREKPYERPSF 1085 Query: 413 SEILEALKKIAEE 375 ++IL +L ++ EE Sbjct: 1086 AQILVSLNRMLEE 1098
>TIE2_MOUSE (Q02858) Angiopoietin-1 receptor precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen) Length = 1122 Score = 44.7 bits (104), Expect = 2e-04 Identities = 25/73 (34%), Positives = 43/73 (58%), Gaps = 1/73 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW +++ G PY T + + Q G R P N ++ +L+++CW++ P ERP F Sbjct: 1025 LLWEIVSLGGTPYCGMTCAELYEKLPQ-GYRLEKPLNCDDEVYDLMRQCWREKPYERPSF 1083 Query: 413 SEILEALKKIAEE 375 ++IL +L ++ EE Sbjct: 1084 AQILVSLNRMLEE 1096
>FLK_RAT (P09760) Tyrosine-protein kinase FLK (EC 2.7.10.2) (Fragment)| Length = 323 Score = 44.3 bits (103), Expect = 3e-04 Identities = 24/74 (32%), Positives = 39/74 (52%), Gaps = 1/74 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW + G PY T QA V ++G R + P+N ++ ++ KCW P RP F Sbjct: 250 LLWETFSLGVCPYPGMTNQQAREQV-ERGYRMSAPQNCPEEIFTIMMKCWDYKPENRPKF 308 Query: 413 SEILEALKKIAEEV 372 S++ + L I +++ Sbjct: 309 SDLHKELTAIKKKI 322
>LTK_MOUSE (P08923) Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1)| Length = 888 Score = 44.3 bits (103), Expect = 3e-04 Identities = 23/73 (31%), Positives = 37/73 (50%), Gaps = 1/73 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW + + G +PY T Q + + G R P+N + ++ +CWQ P RPDF Sbjct: 708 LLWEIFSLGYMPYPGHTN-QEVLDFIATGNRMDPPRNCPGPVYRIMTQCWQHQPELRPDF 766 Query: 413 SEILEALKKIAEE 375 ILE ++ ++ Sbjct: 767 GSILERIQYCTQD 779
>CSK_RAT (P32577) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| Length = 450 Score = 44.3 bits (103), Expect = 3e-04 Identities = 23/70 (32%), Positives = 38/70 (54%), Gaps = 1/70 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW + + G++PY PL+ V V+KG + P + ++++ CW D A RP F Sbjct: 375 LLWEIYSFGRVPYP-RIPLKDVVPRVEKGYKMDAPDGCPPAVYDVMKNCWHLDAATRPTF 433 Query: 413 SEILEALKKI 384 ++ E L+ I Sbjct: 434 LQLREQLEHI 443
>LCK_CHICK (P42683) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (Protein-tyrosine kinase C-TKL) (p56tk1) Length = 507 Score = 44.3 bits (103), Expect = 3e-04 Identities = 26/85 (30%), Positives = 47/85 (55%), Gaps = 1/85 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LL ++T G+IPY T + + +++G R P N +L EL+ +CW++ P ERP F Sbjct: 427 LLTEIVTYGRIPYPGMTNPEV-IQNLERGYRMPQPDNCPQELYELMMQCWKEQPEERPTF 485 Query: 413 SEILEALKKIAEEVGDEHDGKHKDK 339 E +K + E+ +G+++ + Sbjct: 486 ----EYMKSVLEDFFTATEGQYQQQ 506
>BTKL_DROME (P08630) Tyrosine-protein kinase Btk29A (EC 2.7.10.2) (Dsrc28C)| Length = 786 Score = 44.3 bits (103), Expect = 3e-04 Identities = 23/76 (30%), Positives = 42/76 (55%), Gaps = 1/76 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 L+W + T GK+PY + V VQ+G+ PK+ ++ ++++ CW P ERP F Sbjct: 712 LMWEIFTCGKMPYGRLKNTEV-VERVQRGIILEKPKSCAKEIYDVMKLCWSHGPEERPAF 770 Query: 413 SEILEALKKIAEEVGD 366 +++ L +A+ + D Sbjct: 771 RVLMDQLALVAQTLTD 786
>RYK_MOUSE (Q01887) Tyrosine-protein kinase RYK precursor (EC 2.7.10.1)| (Kinase VIK) (NYK-R) (Met-related kinase) Length = 594 Score = 43.9 bits (102), Expect = 3e-04 Identities = 24/74 (32%), Positives = 38/74 (51%), Gaps = 1/74 (1%) Frame = -1 Query: 587 LWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDFS 411 LW L+T G+ PY P + A ++ G R P N +L ++ CW DP ERP F Sbjct: 519 LWELMTLGQTPYVDIDPFEMAA-YLKDGYRIAQPINCPDELFAVMACCWALDPEERPKFQ 577 Query: 410 EILEALKKIAEEVG 369 ++++ L + +G Sbjct: 578 QLVQCLTEFHAALG 591
>MATK_RAT (P41243) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase BATK) Length = 467 Score = 43.9 bits (102), Expect = 3e-04 Identities = 24/75 (32%), Positives = 39/75 (52%), Gaps = 1/75 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW + + G+ PY + L+ V+KG R P + + L+ CW+ +P+ RP F Sbjct: 373 LLWEVFSYGRAPYPKMS-LKEVSEAVEKGYRMEPPDSCPGPVHTLMGSCWEAEPSRRPPF 431 Query: 413 SEILEALKKIAEEVG 369 +I+E L + VG Sbjct: 432 RKIVEKLGRELRSVG 446
>EPHA5_CHICK (P54755) Ephrin type-A receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor CEK7) Length = 1013 Score = 43.9 bits (102), Expect = 3e-04 Identities = 24/70 (34%), Positives = 39/70 (55%), Gaps = 1/70 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 ++W +++ G+ PY T Q + V++G R P + A L +L+ CWQ+D RP F Sbjct: 843 VMWEVMSYGERPYWEMTN-QDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKDRNSRPKF 901 Query: 413 SEILEALKKI 384 EI+ L K+ Sbjct: 902 DEIVSMLDKL 911
>VGFR1_HUMAN (P17948) Vascular endothelial growth factor receptor 1 precursor (EC| 2.7.10.1) (VEGFR-1) (Vascular permeability factor receptor) (Tyrosine-protein kinase receptor FLT) (Flt-1) (Tyrosine-protein kinase FRT) (Fms-like tyrosine kinase 1) Length = 1338 Score = 43.9 bits (102), Expect = 3e-04 Identities = 23/81 (28%), Positives = 44/81 (54%), Gaps = 1/81 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW + + G PY + +++G+R P+ + ++ +++ CW +DP ERP F Sbjct: 1088 LLWEIFSLGGSPYPGVQMDEDFCSRLREGMRMRAPEYSTPEIYQIMLDCWHRDPKERPRF 1147 Query: 413 SEILEALKKIAEEVGDEHDGK 351 +E++E L + + + DGK Sbjct: 1148 AELVEKLGDLL-QANVQQDGK 1167
>ANPRA_RAT (P18910) Atrial natriuretic peptide receptor A precursor (ANP-A)| (ANPRA) (GC-A) (Guanylate cyclase) (EC 4.6.1.2) (NPR-A) (Atrial natriuretic peptide A-type receptor) Length = 1057 Score = 43.9 bits (102), Expect = 3e-04 Identities = 20/48 (41%), Positives = 31/48 (64%), Gaps = 1/48 (2%) Frame = -1 Query: 515 QKGLRPTIPKNAHAK-LTELLQKCWQQDPAERPDFSEILEALKKIAEE 375 Q RP++ +H + L +L+Q+CW +DP ERP F +I AL+K +E Sbjct: 756 QPPFRPSMDLQSHLEELGQLMQRCWAEDPQERPPFQQIRLALRKFNKE 803
>ANPRA_MOUSE (P18293) Atrial natriuretic peptide receptor A precursor (ANP-A)| (ANPRA) (GC-A) (Guanylate cyclase) (EC 4.6.1.2) (NPR-A) (Atrial natriuretic peptide A-type receptor) Length = 1057 Score = 43.9 bits (102), Expect = 3e-04 Identities = 20/48 (41%), Positives = 31/48 (64%), Gaps = 1/48 (2%) Frame = -1 Query: 515 QKGLRPTIPKNAHAK-LTELLQKCWQQDPAERPDFSEILEALKKIAEE 375 Q RP++ +H + L +L+Q+CW +DP ERP F +I AL+K +E Sbjct: 756 QPPFRPSMDLQSHLEELGQLMQRCWAEDPQERPPFQQIRLALRKFNKE 803
>RET_MOUSE (P35546) Proto-oncogene tyrosine-protein kinase receptor ret| precursor (EC 2.7.10.1) (C-ret) Length = 1115 Score = 43.9 bits (102), Expect = 3e-04 Identities = 25/79 (31%), Positives = 44/79 (55%), Gaps = 1/79 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW ++T G PY P + +++ G R P N ++ L+ +CW+Q+P +RP F Sbjct: 941 LLWEIVTLGGNPYPGIPP-ERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVF 999 Query: 413 SEILEALKKIAEEVGDEHD 357 ++I + L+K+ + D D Sbjct: 1000 ADISKDLEKMMVKSRDYLD 1018
>RYK_HUMAN (P34925) Tyrosine-protein kinase RYK precursor (EC 2.7.10.1)| Length = 604 Score = 43.9 bits (102), Expect = 3e-04 Identities = 24/74 (32%), Positives = 38/74 (51%), Gaps = 1/74 (1%) Frame = -1 Query: 587 LWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDFS 411 LW L+T G+ PY P + A ++ G R P N +L ++ CW DP ERP F Sbjct: 529 LWELMTLGQTPYVDIDPFEMAA-YLKDGYRIAQPINCPDELFAVMACCWALDPEERPKFQ 587 Query: 410 EILEALKKIAEEVG 369 ++++ L + +G Sbjct: 588 QLVQCLTEFHAALG 601
>RET_HUMAN (P07949) Proto-oncogene tyrosine-protein kinase receptor ret| precursor (EC 2.7.10.1) (C-ret) Length = 1114 Score = 43.5 bits (101), Expect = 5e-04 Identities = 23/70 (32%), Positives = 41/70 (58%), Gaps = 1/70 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW ++T G PY P + +++ G R P N ++ L+ +CW+Q+P +RP F Sbjct: 940 LLWEIVTLGGNPYPGIPP-ERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVF 998 Query: 413 SEILEALKKI 384 ++I + L+K+ Sbjct: 999 ADISKDLEKM 1008
>FGFR1_XENLA (P22182) Fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) (FGFR-1) Length = 812 Score = 43.5 bits (101), Expect = 5e-04 Identities = 22/70 (31%), Positives = 40/70 (57%), Gaps = 1/70 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW + T G PY P++ ++++G R P N +L +++ CW P++RP F Sbjct: 683 LLWEIFTLGGSPYP-GVPMEELFKLLKEGHRMDKPTNCTNELYMMMKDCWHAMPSQRPTF 741 Query: 413 SEILEALKKI 384 ++++E L +I Sbjct: 742 NQLVEDLDRI 751
>EPHA7_RAT (P54759) Ephrin type-A receptor 7 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) Length = 998 Score = 43.5 bits (101), Expect = 5e-04 Identities = 22/70 (31%), Positives = 41/70 (58%), Gaps = 1/70 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 ++W +++ G+ PY + Q + +++G R P + A L +L+ CWQ++ AERP F Sbjct: 825 VMWEVMSYGERPY-WDMSNQDVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKERAERPKF 883 Query: 413 SEILEALKKI 384 +I+ L K+ Sbjct: 884 EQIVGILDKM 893
>EPHA7_HUMAN (Q15375) Ephrin type-A receptor 7 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Receptor protein-tyrosine kinase HEK11) Length = 998 Score = 43.5 bits (101), Expect = 5e-04 Identities = 22/70 (31%), Positives = 41/70 (58%), Gaps = 1/70 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 ++W +++ G+ PY + Q + +++G R P + A L +L+ CWQ++ AERP F Sbjct: 825 VMWEVMSYGERPY-WDMSNQDVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKERAERPKF 883 Query: 413 SEILEALKKI 384 +I+ L K+ Sbjct: 884 EQIVGILDKM 893
>FAK2_RAT (P70600) Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal| adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) Length = 1009 Score = 43.5 bits (101), Expect = 5e-04 Identities = 23/69 (33%), Positives = 41/69 (59%), Gaps = 1/69 (1%) Frame = -1 Query: 587 LWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDFS 411 +W +L+ GK P+ + + +GV++KG R P+ L L+ +CW DP++RP F+ Sbjct: 615 MWEILSFGKQPF-FWLENKDVIGVLEKGDRLPKPELCPPVLYTLMTRCWDYDPSDRPRFT 673 Query: 410 EILEALKKI 384 E++ +L I Sbjct: 674 ELVCSLSDI 682
>FAK2_MOUSE (Q9QVP9) Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal| adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinas Length = 1009 Score = 43.5 bits (101), Expect = 5e-04 Identities = 23/69 (33%), Positives = 41/69 (59%), Gaps = 1/69 (1%) Frame = -1 Query: 587 LWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDFS 411 +W +L+ GK P+ + + +GV++KG R P+ L L+ +CW DP++RP F+ Sbjct: 615 MWEILSFGKQPF-FWLENKDVIGVLEKGDRLPKPELCPPVLYTLMTRCWDYDPSDRPRFT 673 Query: 410 EILEALKKI 384 E++ +L I Sbjct: 674 ELVCSLSDI 682
>ALK_MOUSE (P97793) ALK tyrosine kinase receptor precursor (EC 2.7.10.1)| (Anaplastic lymphoma kinase) (CD246 antigen) Length = 1621 Score = 43.5 bits (101), Expect = 5e-04 Identities = 23/73 (31%), Positives = 39/73 (53%), Gaps = 1/73 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW + + G +PY + Q + V G R PKN + ++ +CWQ P +RP+F Sbjct: 1322 LLWEIFSLGYMPYPSKSN-QEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNF 1380 Query: 413 SEILEALKKIAEE 375 + ILE ++ ++ Sbjct: 1381 AIILERIEYCTQD 1393
>ALK_HUMAN (Q9UM73) ALK tyrosine kinase receptor precursor (EC 2.7.10.1)| (Anaplastic lymphoma kinase) (CD246 antigen) Length = 1620 Score = 43.5 bits (101), Expect = 5e-04 Identities = 23/73 (31%), Positives = 39/73 (53%), Gaps = 1/73 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW + + G +PY + Q + V G R PKN + ++ +CWQ P +RP+F Sbjct: 1318 LLWEIFSLGYMPYPSKSN-QEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNF 1376 Query: 413 SEILEALKKIAEE 375 + ILE ++ ++ Sbjct: 1377 AIILERIEYCTQD 1389
>CEK3_CHICK (P18461) Tyrosine kinase receptor CEK3 precursor (EC 2.7.10.1)| Length = 823 Score = 43.5 bits (101), Expect = 5e-04 Identities = 22/70 (31%), Positives = 40/70 (57%), Gaps = 1/70 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 L+W + T G PY P++ ++++G R P N +L +++ CWQ P++RP F Sbjct: 694 LMWEIFTLGGSPYP-GIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWQAVPSQRPTF 752 Query: 413 SEILEALKKI 384 +++E L +I Sbjct: 753 KQLVEDLDRI 762
>ANKK1_HUMAN (Q8NFD2) Ankyrin repeat and protein kinase domain-containing| protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288) Length = 765 Score = 43.5 bits (101), Expect = 5e-04 Identities = 23/69 (33%), Positives = 38/69 (55%), Gaps = 7/69 (10%) Frame = -1 Query: 590 LLWXLLTGKIPYEYXTPLQAAVGVVQKGLRPTI-------PKNAHAKLTELLQKCWQQDP 432 ++W LLT K PY + + V G+RP++ P A ++ +L+++CW QDP Sbjct: 215 VIWELLTQKKPYSGFNMMMIIIRVAA-GMRPSLQPVSDQWPSEAQ-QMVDLMKRCWDQDP 272 Query: 431 AERPDFSEI 405 +RP F +I Sbjct: 273 KKRPCFLDI 281
>EPHA5_MOUSE (Q60629) Ephrin type-A receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Brain-specific kinase) (CEK-7) Length = 877 Score = 43.5 bits (101), Expect = 5e-04 Identities = 24/70 (34%), Positives = 39/70 (55%), Gaps = 1/70 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 ++W +++ G+ PY T Q + V++G R P + A L +L+ CWQ+D RP F Sbjct: 706 VMWEVVSYGERPYWEMTN-QDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKDRNSRPKF 764 Query: 413 SEILEALKKI 384 EI+ L K+ Sbjct: 765 DEIVNMLDKL 774
>FYN_XIPHE (P27446) Proto-oncogene tyrosine-protein kinase FYN (EC 2.7.10.2)| (P59-FYN) Length = 536 Score = 43.5 bits (101), Expect = 5e-04 Identities = 26/66 (39%), Positives = 40/66 (60%), Gaps = 1/66 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LL L+T G++PY + + V++G R P++ A L EL+ +CW++DP ERP F Sbjct: 454 LLTELVTKGRVPYPGMNNREV-LEQVERGYRMPCPQDCPASLHELMLQCWKKDPEERPTF 512 Query: 413 SEILEA 396 E L+A Sbjct: 513 -EYLQA 517
>INSRR_CAVPO (P14617) Insulin receptor-related protein precursor (EC 2.7.10.1)| (IRR) (IR-related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain] Length = 1300 Score = 43.1 bits (100), Expect = 6e-04 Identities = 23/69 (33%), Positives = 40/69 (57%), Gaps = 1/69 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 +LW ++T + PY+ + Q V+ G+ + H +L EL+ CWQQ+P RP F Sbjct: 1181 VLWEIVTLAEQPYQGLSNEQVLKFVMDGGVLEELEDCPH-QLQELMSSCWQQNPRLRPTF 1239 Query: 413 SEILEALKK 387 ++IL +++K Sbjct: 1240 TQILNSIQK 1248
>FGFR1_CHICK (P21804) Basic fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) Length = 819 Score = 43.1 bits (100), Expect = 6e-04 Identities = 22/70 (31%), Positives = 39/70 (55%), Gaps = 1/70 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW + T G PY P++ ++++G R P N +L +++ CW P++RP F Sbjct: 687 LLWEIFTLGGSPYP-GVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTF 745 Query: 413 SEILEALKKI 384 +++E L +I Sbjct: 746 KQLVEDLDRI 755
>BTK_HUMAN (Q06187) Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton's| tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) Length = 658 Score = 43.1 bits (100), Expect = 6e-04 Identities = 24/73 (32%), Positives = 38/73 (52%), Gaps = 1/73 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 L+W + + GK+PYE T + A + Q GLR P A K+ ++ CW + ERP F Sbjct: 585 LMWEIYSLGKMPYERFTNSETAEHIAQ-GLRLYRPHLASEKVYTIMYSCWHEKADERPTF 643 Query: 413 SEILEALKKIAEE 375 +L + + +E Sbjct: 644 KILLSNILDVMDE 656
>MATK_HUMAN (P42679) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase) Length = 507 Score = 43.1 bits (100), Expect = 6e-04 Identities = 23/75 (30%), Positives = 37/75 (49%), Gaps = 1/75 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW + + G+ PY + L+ V+KG R P+ + L+ CW+ +PA RP F Sbjct: 413 LLWEVFSYGRAPYPKMS-LKEVSEAVEKGYRMEPPEGCPGPVHVLMSSCWEAEPARRPPF 471 Query: 413 SEILEALKKIAEEVG 369 ++ E L + G Sbjct: 472 RKLAEKLARELRSAG 486
>FGFR1_MOUSE (P16092) Basic fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) (FGFR-1) (bFGF-R) (MFR) Length = 822 Score = 43.1 bits (100), Expect = 6e-04 Identities = 22/70 (31%), Positives = 39/70 (55%), Gaps = 1/70 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW + T G PY P++ ++++G R P N +L +++ CW P++RP F Sbjct: 689 LLWEIFTLGGSPYP-GVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTF 747 Query: 413 SEILEALKKI 384 +++E L +I Sbjct: 748 KQLVEDLDRI 757
>FGFR1_HUMAN (P11362) Basic fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) (FGFR-1) (bFGF-R) (Fms-like tyrosine kinase 2) (c-fgr) (CD331 antigen) Length = 822 Score = 43.1 bits (100), Expect = 6e-04 Identities = 22/70 (31%), Positives = 39/70 (55%), Gaps = 1/70 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW + T G PY P++ ++++G R P N +L +++ CW P++RP F Sbjct: 689 LLWEIFTLGGSPYP-GVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTF 747 Query: 413 SEILEALKKI 384 +++E L +I Sbjct: 748 KQLVEDLDRI 757
>FER_HUMAN (P16591) Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2)| (p94-FER) (c-FER) Length = 822 Score = 43.1 bits (100), Expect = 6e-04 Identities = 24/74 (32%), Positives = 39/74 (52%), Gaps = 1/74 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW + G PY T QA V ++G R + P++ +++++ KCW P RP F Sbjct: 749 LLWETFSLGVCPYPGMTNQQAREQV-ERGYRMSAPQHCPEDISKIMMKCWDYKPENRPKF 807 Query: 413 SEILEALKKIAEEV 372 SE+ + L I ++ Sbjct: 808 SELQKELTIIKRKL 821
>EPHA3_HUMAN (P29320) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ETK1) (HEK) (HEK4) Length = 983 Score = 43.1 bits (100), Expect = 6e-04 Identities = 24/75 (32%), Positives = 39/75 (52%), Gaps = 1/75 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 +LW +++ G+ PY + Q + V +G R P + A L +L+ CWQ+D RP F Sbjct: 813 VLWEVMSYGERPY-WEMSNQDVIKAVDEGYRLPPPMDCPAALYQLMLDCWQKDRNNRPKF 871 Query: 413 SEILEALKKIAEEVG 369 +I+ L K+ G Sbjct: 872 EQIVSILDKLIRNPG 886
>EPHA3_CHICK (P29318) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ETK1) (CEK4) Length = 983 Score = 43.1 bits (100), Expect = 6e-04 Identities = 23/70 (32%), Positives = 38/70 (54%), Gaps = 1/70 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 +LW +++ G+ PY + Q + V +G R P + A L +L+ CWQ+D RP F Sbjct: 813 VLWEVMSYGERPY-WEMSFQDVIKAVDEGYRLPPPMDCPAALYQLMLDCWQKDRNNRPKF 871 Query: 413 SEILEALKKI 384 +I+ L K+ Sbjct: 872 EQIVSILDKL 881
>ANPRB_HUMAN (P20594) Atrial natriuretic peptide receptor B precursor (ANP-B)| (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor) Length = 1047 Score = 43.1 bits (100), Expect = 6e-04 Identities = 19/46 (41%), Positives = 31/46 (67%), Gaps = 1/46 (2%) Frame = -1 Query: 503 RPTIPKNA-HAKLTELLQKCWQQDPAERPDFSEILEALKKIAEEVG 369 RP+I + + +L L+++CW QDPAERPDF +I +++ +E G Sbjct: 749 RPSIDRTQLNEELVLLMERCWAQDPAERPDFGQIKGFIRRFNKEGG 794
>ANPRB_BOVIN (P46197) Atrial natriuretic peptide receptor B precursor (ANP-B)| (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor) Length = 1047 Score = 43.1 bits (100), Expect = 6e-04 Identities = 19/46 (41%), Positives = 31/46 (67%), Gaps = 1/46 (2%) Frame = -1 Query: 503 RPTIPKNA-HAKLTELLQKCWQQDPAERPDFSEILEALKKIAEEVG 369 RP+I + + +L L+++CW QDPAERPDF +I +++ +E G Sbjct: 749 RPSIDRTQLNEELVLLMERCWAQDPAERPDFGQIKGFIRRFNKEGG 794
>EPHA2_HUMAN (P29317) Ephrin type-A receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) Length = 976 Score = 42.7 bits (99), Expect = 8e-04 Identities = 20/70 (28%), Positives = 39/70 (55%), Gaps = 1/70 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 ++W ++T G+ PY + + + G R P + + + +L+ +CWQQ+ A RP F Sbjct: 806 VMWEVMTYGERPY-WELSNHEVMKAINDGFRLPTPMDCPSAIYQLMMQCWQQERARRPKF 864 Query: 413 SEILEALKKI 384 ++I+ L K+ Sbjct: 865 ADIVSILDKL 874
>RIPK4_HUMAN (P57078) Receptor-interacting serine/threonine-protein kinase 4 (EC| 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase) Length = 832 Score = 42.7 bits (99), Expect = 8e-04 Identities = 23/65 (35%), Positives = 33/65 (50%), Gaps = 6/65 (9%) Frame = -1 Query: 590 LLWXLLTGKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAK------LTELLQKCWQQDPA 429 ++W +LT K P+ + + V KG RP +P A+ L L+Q+CWQ DP Sbjct: 212 VIWGVLTQKKPFADEKNILHIMVKVVKGHRPELPPVCRARPRACSHLIRLMQRCWQGDPR 271 Query: 428 ERPDF 414 RP F Sbjct: 272 VRPTF 276
>ABL_FSVHY (P10447) Tyrosine-protein kinase transforming protein Abl (EC| 2.7.10.2) (V-abl) Length = 439 Score = 42.7 bits (99), Expect = 8e-04 Identities = 23/63 (36%), Positives = 35/63 (55%), Gaps = 1/63 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW + T G PY L +++K R P+ K+ EL++ CWQ +P++RP F Sbjct: 377 LLWEIATYGMSPYP-GIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPAF 435 Query: 413 SEI 405 +EI Sbjct: 436 AEI 438
>ROS_HUMAN (P08922) Proto-oncogene tyrosine-protein kinase ROS precursor (EC| 2.7.10.1) (c-ros-1) Length = 2347 Score = 42.7 bits (99), Expect = 8e-04 Identities = 25/68 (36%), Positives = 35/68 (51%), Gaps = 1/68 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 L+W +LT G PY + L + VQ G R P+N L L+ +CW Q+P +RP F Sbjct: 2150 LIWEILTLGHQPYPAHSNLDV-LNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTF 2208 Query: 413 SEILEALK 390 I L+ Sbjct: 2209 HRIQNQLQ 2216
>M3K13_PONPY (Q5R8X7) Mitogen-activated protein kinase kinase kinase 13 (EC| 2.7.11.25) Length = 966 Score = 42.4 bits (98), Expect = 0.001 Identities = 23/73 (31%), Positives = 33/73 (45%) Frame = -1 Query: 590 LLWXLLTGKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDFS 411 +LW LLTG+IPY+ GV L +P L+++ WQ P RP F Sbjct: 342 VLWELLTGEIPYKDVDSSAIIWGVGSNSLHLPVPSTCPDGFKILMKQTWQSKPRNRPSFR 401 Query: 410 EILEALKKIAEEV 372 + L L + +V Sbjct: 402 QTLMHLDIASADV 414
>M3K13_HUMAN (O43283) Mitogen-activated protein kinase kinase kinase 13 (EC| 2.7.11.25) (Mixed lineage kinase) (MLK) (Leucine zipper-bearing kinase) Length = 966 Score = 42.4 bits (98), Expect = 0.001 Identities = 23/73 (31%), Positives = 33/73 (45%) Frame = -1 Query: 590 LLWXLLTGKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDFS 411 +LW LLTG+IPY+ GV L +P L+++ WQ P RP F Sbjct: 342 VLWELLTGEIPYKDVDSSAIIWGVGSNSLHLPVPSTCPDGFKILMKQTWQSKPRNRPSFR 401 Query: 410 EILEALKKIAEEV 372 + L L + +V Sbjct: 402 QTLMHLDIASADV 414
>TIE1_BRARE (O73792) Tyrosine-protein kinase receptor Tie-1 (EC 2.7.10.1)| (Fragment) Length = 184 Score = 42.4 bits (98), Expect = 0.001 Identities = 25/72 (34%), Positives = 40/72 (55%), Gaps = 1/72 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW +++ G PY T + + Q G R P+N ++ EL+++CW+ P ERP F Sbjct: 88 LLWEIVSLGGTPYCGMTCAELYEKLPQ-GYRMEQPRNCDDEVYELMRQCWRDRPYERPPF 146 Query: 413 SEILEALKKIAE 378 S+I L ++ E Sbjct: 147 SQISVQLNRMQE 158
>FAK2_HUMAN (Q14289) Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal| adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinas Length = 1009 Score = 42.4 bits (98), Expect = 0.001 Identities = 22/69 (31%), Positives = 40/69 (57%), Gaps = 1/69 (1%) Frame = -1 Query: 587 LWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDFS 411 +W +L+ GK P+ + + +GV++KG R P L L+ +CW DP++RP F+ Sbjct: 615 MWEILSFGKQPF-FWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTRCWDYDPSDRPRFT 673 Query: 410 EILEALKKI 384 E++ +L + Sbjct: 674 ELVCSLSDV 682
>IGF1R_HUMAN (P08069) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 recepto Length = 1367 Score = 42.4 bits (98), Expect = 0.001 Identities = 25/72 (34%), Positives = 39/72 (54%), Gaps = 1/72 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 +LW + T + PY+ + Q V++ GL P N L EL++ CWQ +P RP F Sbjct: 1201 VLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDK-PDNCPDMLFELMRMCWQYNPKMRPSF 1259 Query: 413 SEILEALKKIAE 378 EI+ ++K+ E Sbjct: 1260 LEIISSIKEEME 1271
>EPHA5_RAT (P54757) Ephrin type-A receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) Length = 1005 Score = 42.4 bits (98), Expect = 0.001 Identities = 23/70 (32%), Positives = 39/70 (55%), Gaps = 1/70 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 ++W +++ G+ PY T Q + V++G R P + A L +L+ CWQ+D RP F Sbjct: 869 VMWEVVSYGERPYWEMTN-QDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKDRNSRPKF 927 Query: 413 SEILEALKKI 384 +I+ L K+ Sbjct: 928 DDIVNMLDKL 937
>BTK_MOUSE (P35991) Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton's| tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB) Length = 658 Score = 42.4 bits (98), Expect = 0.001 Identities = 23/73 (31%), Positives = 38/73 (52%), Gaps = 1/73 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 L+W + + GK+PYE T + A + Q GLR P A ++ ++ CW + ERP F Sbjct: 585 LMWEIYSLGKMPYERFTNSETAEHIAQ-GLRLYRPHLASERVYTIMYSCWHEKADERPSF 643 Query: 413 SEILEALKKIAEE 375 +L + + +E Sbjct: 644 KILLSNILDVMDE 656
>FGFR3_HUMAN (P22607) Fibroblast growth factor receptor 3 precursor (EC| 2.7.10.1) (FGFR-3) (CD333 antigen) Length = 806 Score = 42.4 bits (98), Expect = 0.001 Identities = 21/70 (30%), Positives = 39/70 (55%), Gaps = 1/70 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW + T G PY P++ ++++G R P N L ++++CW P++RP F Sbjct: 683 LLWEIFTLGGSPYP-GIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTF 741 Query: 413 SEILEALKKI 384 +++E L ++ Sbjct: 742 KQLVEDLDRV 751
>ANKK1_MOUSE (Q8BZ25) Ankyrin repeat and protein kinase domain-containing| protein 1 (EC 2.7.11.1) Length = 745 Score = 42.0 bits (97), Expect = 0.001 Identities = 21/69 (30%), Positives = 37/69 (53%), Gaps = 7/69 (10%) Frame = -1 Query: 590 LLWXLLTGKIPYEYXTPLQAAVGVVQKGLRPTI-------PKNAHAKLTELLQKCWQQDP 432 ++W +LT K PY + + V G+RP++ P+ H ++ L+++CW QDP Sbjct: 227 VIWEILTQKKPYAGLNMMTIIIRVAA-GMRPSLQDVSDEWPEEVH-QMVNLMKRCWDQDP 284 Query: 431 AERPDFSEI 405 +RP F + Sbjct: 285 KKRPCFLNV 293
>RYK1_DROME (Q27324) Tyrosine-protein kinase Drl precursor (EC 2.7.10.1)| (Protein derailed) Length = 610 Score = 42.0 bits (97), Expect = 0.001 Identities = 23/74 (31%), Positives = 37/74 (50%), Gaps = 1/74 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 L+W + T GK+PY P + ++ G R P N +L ++ CW PAERP F Sbjct: 534 LMWEMCTLGKLPYAEIDPYEME-HYLKDGYRLAQPFNCPDELFTIMAYCWASMPAERPSF 592 Query: 413 SEILEALKKIAEEV 372 S++ L + ++ Sbjct: 593 SQLQICLSEFHTQI 606
>EPHA7_CHICK (O42422) Ephrin type-A receptor 7 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor CEPHA7) (Tyrosine-protein kinase receptor CEK11) Length = 993 Score = 42.0 bits (97), Expect = 0.001 Identities = 21/70 (30%), Positives = 40/70 (57%), Gaps = 1/70 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 ++W +++ G+ PY + Q + +++G R P + A L +L+ CWQ++ ERP F Sbjct: 820 VMWEVMSYGERPY-WDMSNQDVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKERGERPKF 878 Query: 413 SEILEALKKI 384 +I+ L K+ Sbjct: 879 EQIVGILDKM 888
>CEK2_CHICK (P18460) Tyrosine kinase receptor CEK2 precursor (EC 2.7.10.1)| Length = 806 Score = 42.0 bits (97), Expect = 0.001 Identities = 21/70 (30%), Positives = 39/70 (55%), Gaps = 1/70 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW + T G PY P++ ++++G R P N L ++++CW P++RP F Sbjct: 677 LLWEIFTLGGSPYP-GIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAVPSQRPTF 735 Query: 413 SEILEALKKI 384 +++E L ++ Sbjct: 736 KQLVEDLDRV 745
>PTK7_HUMAN (Q13308) Tyrosine-protein kinase-like 7 precursor (Colon carcinoma| kinase 4) (CCK-4) Length = 1070 Score = 42.0 bits (97), Expect = 0.001 Identities = 22/67 (32%), Positives = 34/67 (50%), Gaps = 1/67 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 L+W + T G++P+ + + R P+ +KL L+Q+CW P +RP F Sbjct: 995 LMWEVFTHGEMPHGGQADDEVLADLQAGKARLPQPEGCPSKLYRLMQRCWALSPKDRPSF 1054 Query: 413 SEILEAL 393 SEI AL Sbjct: 1055 SEIASAL 1061
>EPHA5_HUMAN (P54756) Ephrin type-A receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Receptor protein-tyrosine kinase HEK7) Length = 1037 Score = 42.0 bits (97), Expect = 0.001 Identities = 23/70 (32%), Positives = 39/70 (55%), Gaps = 1/70 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 ++W +++ G+ PY T Q + V++G R P + A L +L+ CWQ++ RP F Sbjct: 867 VMWEVVSYGERPYWEMTN-QDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKERNSRPKF 925 Query: 413 SEILEALKKI 384 EI+ L K+ Sbjct: 926 DEIVNMLDKL 935
>ANPRB_RAT (P16067) Atrial natriuretic peptide receptor B precursor (ANP-B)| (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor) Length = 1047 Score = 41.6 bits (96), Expect = 0.002 Identities = 18/46 (39%), Positives = 30/46 (65%), Gaps = 1/46 (2%) Frame = -1 Query: 503 RPTIPKNA-HAKLTELLQKCWQQDPAERPDFSEILEALKKIAEEVG 369 RP+I + + +L L+++CW QDP ERPDF +I +++ +E G Sbjct: 749 RPSIDRTQLNEELVLLMERCWAQDPTERPDFGQIKGFIRRFNKEGG 794
>ANPRB_MOUSE (Q6VVW5) Atrial natriuretic peptide receptor B precursor (ANP-B)| (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor) Length = 1047 Score = 41.6 bits (96), Expect = 0.002 Identities = 18/46 (39%), Positives = 30/46 (65%), Gaps = 1/46 (2%) Frame = -1 Query: 503 RPTIPKNA-HAKLTELLQKCWQQDPAERPDFSEILEALKKIAEEVG 369 RP+I + + +L L+++CW QDP ERPDF +I +++ +E G Sbjct: 749 RPSIDRTQLNEELVLLMERCWAQDPTERPDFGQIKGFIRRFNKEGG 794
>SRC42_DROME (Q9V9J3) Tyrosine-protein kinase Src42A (EC 2.7.10.2) (Dsrc41)| Length = 517 Score = 41.6 bits (96), Expect = 0.002 Identities = 23/63 (36%), Positives = 33/63 (52%), Gaps = 1/63 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LL L+T G+IPY T + V + G R P N +L E++ +CW +DP RP F Sbjct: 435 LLTELVTYGRIPYPGMTNAEVLTQV-EHGYRMPQPPNCEPRLYEIMLECWHKDPMRRPTF 493 Query: 413 SEI 405 + Sbjct: 494 ETL 496
>BMX_MOUSE (P97504) Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2)| (Bone marrow tyrosine kinase gene in chromosome X protein homolog) Length = 651 Score = 41.6 bits (96), Expect = 0.002 Identities = 22/73 (30%), Positives = 40/73 (54%), Gaps = 1/73 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 L+W + + GK PY+ + V V Q G R P+ A + +++ CW + P +RP F Sbjct: 577 LMWEVFSLGKQPYDLYDNSEVVVKVSQ-GHRLYRPQLASDTIYQIMYSCWHELPEKRPTF 635 Query: 413 SEILEALKKIAEE 375 ++L A++ + E+ Sbjct: 636 QQLLSAIEPLREQ 648
>EPA4B_XENLA (Q91694) Ephrin type-A receptor 4-B precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor PAG) (Pagliaccio) Length = 985 Score = 41.6 bits (96), Expect = 0.002 Identities = 20/70 (28%), Positives = 40/70 (57%), Gaps = 1/70 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 ++W +++ G+ PY + Q + +++G R P + L +L+ CWQ+D ++RP F Sbjct: 812 VMWEVMSYGERPY-WDMSNQDVIKAIEEGYRLPPPMDCPIALHQLMLDCWQKDRSDRPKF 870 Query: 413 SEILEALKKI 384 +I+ L K+ Sbjct: 871 GQIVSMLDKL 880
>FGFR2_MOUSE (P21803) Fibroblast growth factor receptor 2 precursor (EC| 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor) Length = 821 Score = 41.6 bits (96), Expect = 0.002 Identities = 21/70 (30%), Positives = 39/70 (55%), Gaps = 1/70 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 L+W + T G PY P++ ++++G R P N +L +++ CW P++RP F Sbjct: 692 LMWEIFTLGGSPYP-GIPVEELFKLLKEGHRMDKPTNCTNELYMMMRDCWHAVPSQRPTF 750 Query: 413 SEILEALKKI 384 +++E L +I Sbjct: 751 KQLVEDLDRI 760
>FGFR2_HUMAN (P21802) Fibroblast growth factor receptor 2 precursor (EC| 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor 2) (CD332 antigen) Length = 821 Score = 41.6 bits (96), Expect = 0.002 Identities = 21/70 (30%), Positives = 39/70 (55%), Gaps = 1/70 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 L+W + T G PY P++ ++++G R P N +L +++ CW P++RP F Sbjct: 692 LMWEIFTLGGSPYP-GIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTF 750 Query: 413 SEILEALKKI 384 +++E L +I Sbjct: 751 KQLVEDLDRI 760
>EPHA2_MOUSE (Q03145) Ephrin type-A receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2) Length = 977 Score = 41.6 bits (96), Expect = 0.002 Identities = 19/70 (27%), Positives = 39/70 (55%), Gaps = 1/70 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 ++W ++T G+ PY + + + G R P + + + +L+ +CWQQ+ + RP F Sbjct: 807 VMWEVMTYGERPY-WELSNHEVMKAINDGFRLPTPMDCPSAIYQLMMQCWQQERSRRPKF 865 Query: 413 SEILEALKKI 384 ++I+ L K+ Sbjct: 866 ADIVSILDKL 875
>IGF1R_BOVIN (Q05688) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] (F Length = 640 Score = 41.2 bits (95), Expect = 0.002 Identities = 24/68 (35%), Positives = 37/68 (54%), Gaps = 1/68 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 +LW + T + PY+ + Q V++ GL P N L EL++ CWQ +P RP F Sbjct: 474 VLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDK-PDNCPDMLFELMRMCWQYNPKMRPSF 532 Query: 413 SEILEALK 390 EI+ ++K Sbjct: 533 LEIISSVK 540
>YES_AVISY (P00527) Tyrosine-protein kinase transforming protein YES (EC| 2.7.10.2) (Fragment) Length = 528 Score = 41.2 bits (95), Expect = 0.002 Identities = 24/68 (35%), Positives = 37/68 (54%), Gaps = 1/68 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LL L+T G++PY + + V++G R P+ L EL++ CW++DP ERP F Sbjct: 451 LLTELVTKGRVPYPGMVNREV-LEQVERGYRMPCPQGCPESLHELMKLCWKKDPDERPTF 509 Query: 413 SEILEALK 390 I L+ Sbjct: 510 EYIQSFLE 517
>YES_CHICK (P09324) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 540 Score = 41.2 bits (95), Expect = 0.002 Identities = 24/68 (35%), Positives = 37/68 (54%), Gaps = 1/68 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LL L+T G++PY + + V++G R P+ L EL++ CW++DP ERP F Sbjct: 458 LLTELVTKGRVPYPGMVNREV-LEQVERGYRMPCPQGCPESLHELMKLCWKKDPDERPTF 516 Query: 413 SEILEALK 390 I L+ Sbjct: 517 EYIQSFLE 524
>VGFR2_MOUSE (P35918) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Protein-tyrosine kinase receptor flk-1) (Fetal liver kinase 1) (Kinase NYK) Length = 1367 Score = 41.2 bits (95), Expect = 0.002 Identities = 23/81 (28%), Positives = 40/81 (49%), Gaps = 1/81 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW + + G PY + +++G R P ++ + + CW +DP +RP F Sbjct: 1092 LLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHEDPNQRPSF 1151 Query: 413 SEILEALKKIAEEVGDEHDGK 351 SE++E L + + + DGK Sbjct: 1152 SELVEHLGNLL-QANAQQDGK 1171
>ANPRB_ANGJA (P55202) Atrial natriuretic peptide receptor B precursor (ANP-B)| (ANPRB) (GC-B) (Guanylate cyclase) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor) Length = 1050 Score = 41.2 bits (95), Expect = 0.002 Identities = 19/44 (43%), Positives = 30/44 (68%), Gaps = 1/44 (2%) Frame = -1 Query: 503 RPTIPKNAHAK-LTELLQKCWQQDPAERPDFSEILEALKKIAEE 375 RPT + H++ L+ L++ CW +DPA+RPDFS I + K+ +E Sbjct: 753 RPTTDTSCHSEELSILMEGCWAEDPADRPDFSYIKIFVMKLNKE 796
>ABL_DROME (P00522) Tyrosine-protein kinase Abl (EC 2.7.10.2) (Abelson| protein) (D-ash) Length = 1620 Score = 41.2 bits (95), Expect = 0.002 Identities = 24/73 (32%), Positives = 36/73 (49%), Gaps = 1/73 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW + T G PY L + KG R P ++ +L+++CWQ D +RP F Sbjct: 557 LLWEIATYGMSPYP-AIDLTDVYHKLDKGYRMERPPGCPPEVYDLMRQCWQWDATDRPTF 615 Query: 413 SEILEALKKIAEE 375 I AL+ + +E Sbjct: 616 KSIHHALEHMFQE 628
>7LESS_DROVI (P20806) Protein sevenless (EC 2.7.10.1)| Length = 2594 Score = 41.2 bits (95), Expect = 0.002 Identities = 23/74 (31%), Positives = 38/74 (51%), Gaps = 1/74 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 L W + T G+ PY + + V++G R P+ KL LL +CW+ +P ERP F Sbjct: 2427 LCWEIFTLGQQPYAARNNFEV-LAHVKEGGRLQQPERCPEKLYALLLQCWRSEPWERPSF 2485 Query: 413 SEILEALKKIAEEV 372 L L+ ++ ++ Sbjct: 2486 KRCLSTLQALSSDL 2499
>EPHA8_RAT (P29321) Ephrin type-A receptor 8 (EC 2.7.10.1) (Tyrosine-protein| kinase receptor EEK) (EPH- and ELK-related kinase) (Fragment) Length = 372 Score = 41.2 bits (95), Expect = 0.002 Identities = 22/70 (31%), Positives = 37/70 (52%), Gaps = 1/70 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 ++W +L G+ PY T Q + V++G R P L +L+ CW +D A+RP F Sbjct: 194 VMWEVLAYGERPYWNMTN-QDVISSVEEGYRLPAPMGCPRALHQLMLDCWHKDRAQRPRF 252 Query: 413 SEILEALKKI 384 S ++ L+ + Sbjct: 253 SHVVSVLEAL 262
>IGF1R_RAT (P24062) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] Length = 1370 Score = 40.8 bits (94), Expect = 0.003 Identities = 24/68 (35%), Positives = 37/68 (54%), Gaps = 1/68 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 +LW + T + PY+ + Q V++ GL P N L EL++ CWQ +P RP F Sbjct: 1202 VLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDK-PDNCPDMLFELMRMCWQYNPKMRPSF 1260 Query: 413 SEILEALK 390 EI+ ++K Sbjct: 1261 LEIIGSIK 1268
>LTK_HUMAN (P29376) Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1)| (Protein tyrosine kinase 1) Length = 864 Score = 40.8 bits (94), Expect = 0.003 Identities = 23/73 (31%), Positives = 37/73 (50%), Gaps = 1/73 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW + + G +PY T Q + V G R P+ + ++ +CWQ +P RP F Sbjct: 712 LLWEIFSLGYMPYPGRTN-QEVLDFVVGGGRMDPPRGCPGPVYRIMTQCWQHEPELRPSF 770 Query: 413 SEILEALKKIAEE 375 + ILE L+ ++ Sbjct: 771 ASILERLQYCTQD 783
>KIT_CHICK (Q08156) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 960 Score = 40.8 bits (94), Expect = 0.003 Identities = 18/69 (26%), Positives = 38/69 (55%), Gaps = 1/69 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW L + G PY ++++G R P+ + ++ ++++ CW DP +RP F Sbjct: 843 LLWELFSLGSSPYPGMPVDSKFYKMIKEGYRMFSPECSPPEMYDIMKSCWDADPLQRPTF 902 Query: 413 SEILEALKK 387 +I++ +++ Sbjct: 903 KQIVQLIEQ 911
>IGF1R_MOUSE (Q60751) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] Length = 1373 Score = 40.8 bits (94), Expect = 0.003 Identities = 24/68 (35%), Positives = 37/68 (54%), Gaps = 1/68 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 +LW + T + PY+ + Q V++ GL P N L EL++ CWQ +P RP F Sbjct: 1203 VLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDK-PDNCPDMLFELMRMCWQYNPKMRPSF 1261 Query: 413 SEILEALK 390 EI+ ++K Sbjct: 1262 LEIIGSIK 1269
>ROS_AVISU (P00529) Tyrosine-protein kinase transforming protein ros (EC| 2.7.10.1) Length = 402 Score = 40.8 bits (94), Expect = 0.003 Identities = 24/70 (34%), Positives = 37/70 (52%), Gaps = 1/70 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 L+W LT G+ PY + ++ + V+ G R P N + +L+ +CW QDP RP F Sbjct: 304 LVWETLTLGQQPYPGLSNIEV-LHHVRSGGRLESPNNCPDDIRDLMTRCWAQDPHNRPTF 362 Query: 413 SEILEALKKI 384 I L++I Sbjct: 363 FYIQHKLQEI 372
>FGFR1_DROME (Q07407) Fibroblast growth factor receptor homolog 1 precursor (EC| 2.7.10.1) (Protein heartless) Length = 729 Score = 40.8 bits (94), Expect = 0.003 Identities = 22/79 (27%), Positives = 38/79 (48%), Gaps = 1/79 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW ++T G+ PY + + G R P + L+++CW + +RP F Sbjct: 622 LLWEIMTYGQQPYPTIMSAEELYTYLMSGQRMEKPAKCSMNIYILMRQCWHFNADDRPPF 681 Query: 413 SEILEALKKIAEEVGDEHD 357 +EI+E + K+ + D D Sbjct: 682 TEIVEYMDKLLQTKEDYLD 700
>IGF1R_XENLA (O73798) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (xIGF-1R) (xIGFR) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] Length = 1358 Score = 40.8 bits (94), Expect = 0.003 Identities = 24/68 (35%), Positives = 37/68 (54%), Gaps = 1/68 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 +LW + T + PY+ + Q V++ GL P N L EL++ CWQ +P RP F Sbjct: 1197 VLWEIATLAEQPYQGMSNEQVLRFVMEGGLLEK-PDNCPDMLFELMRMCWQFNPKMRPSF 1255 Query: 413 SEILEALK 390 EI+ ++K Sbjct: 1256 LEIISSIK 1263
>FGFR2_XENLA (Q03364) Fibroblast growth factor receptor 2 precursor (EC| 2.7.10.1) (FGFR-2) Length = 813 Score = 40.8 bits (94), Expect = 0.003 Identities = 21/70 (30%), Positives = 38/70 (54%), Gaps = 1/70 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 L+W + T G PY P++ ++++G R P N +L +++ CW P+ RP F Sbjct: 682 LMWEIFTLGGSPYP-GIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAIPSHRPTF 740 Query: 413 SEILEALKKI 384 +++E L +I Sbjct: 741 KQLVEDLDRI 750
>PGFRA_HUMAN (P16234) Alpha platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-alpha) (CD140a antigen) Length = 1089 Score = 40.8 bits (94), Expect = 0.003 Identities = 23/70 (32%), Positives = 36/70 (51%), Gaps = 4/70 (5%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW + + G PY ++ G R P +A +++ E++ KCW +P +RP F Sbjct: 884 LLWEIFSLGGTPYPGMMVDSTFYNKIKSGYRMAKPDHATSEVYEIMVKCWNSEPEKRPSF 943 Query: 413 ---SEILEAL 393 SEI+E L Sbjct: 944 YHLSEIVENL 953
>ROS_CHICK (P08941) Proto-oncogene tyrosine-protein kinase ROS precursor (EC| 2.7.10.1) (c-ros-1) Length = 2311 Score = 40.8 bits (94), Expect = 0.003 Identities = 24/70 (34%), Positives = 37/70 (52%), Gaps = 1/70 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 L+W LT G+ PY + ++ + V+ G R P N + +L+ +CW QDP RP F Sbjct: 2167 LVWETLTLGQQPYPGLSNIEV-LHHVRSGGRLESPNNCPDDIRDLMTRCWAQDPHNRPTF 2225 Query: 413 SEILEALKKI 384 I L++I Sbjct: 2226 FYIQHKLQEI 2235
>EPHB1_RAT (P09759) Ephrin type-B receptor 1 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-2) (ELK) Length = 984 Score = 40.8 bits (94), Expect = 0.003 Identities = 21/70 (30%), Positives = 39/70 (55%), Gaps = 1/70 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 ++W +++ G+ PY + Q + +++ R P + A L +L+ CWQ+D RP F Sbjct: 813 VMWEVMSFGERPY-WDMSNQDVINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRF 871 Query: 413 SEILEALKKI 384 +EI+ L K+ Sbjct: 872 AEIVNTLDKM 881
>EPHB1_HUMAN (P54762) Ephrin type-B receptor 1 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK) Length = 984 Score = 40.8 bits (94), Expect = 0.003 Identities = 21/70 (30%), Positives = 39/70 (55%), Gaps = 1/70 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 ++W +++ G+ PY + Q + +++ R P + A L +L+ CWQ+D RP F Sbjct: 813 VMWEVMSFGERPY-WDMSNQDVINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRF 871 Query: 413 SEILEALKKI 384 +EI+ L K+ Sbjct: 872 AEIVNTLDKM 881
>ANPRA_HUMAN (P16066) Atrial natriuretic peptide receptor A precursor (ANP-A)| (ANPRA) (GC-A) (Guanylate cyclase) (EC 4.6.1.2) (NPR-A) (Atrial natriuretic peptide A-type receptor) Length = 1061 Score = 40.4 bits (93), Expect = 0.004 Identities = 19/48 (39%), Positives = 28/48 (58%), Gaps = 1/48 (2%) Frame = -1 Query: 515 QKGLRPTIPKNAHAK-LTELLQKCWQQDPAERPDFSEILEALKKIAEE 375 Q RP++ +H + L L+Q+CW +DP ERP F +I L+K E Sbjct: 760 QPPFRPSLALQSHLEELGLLMQRCWAEDPQERPPFQQIRLTLRKFNRE 807
>VGFR3_MOUSE (P35917) Vascular endothelial growth factor receptor 3 precursor (EC| 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4) Length = 1363 Score = 40.4 bits (93), Expect = 0.004 Identities = 22/83 (26%), Positives = 40/83 (48%), Gaps = 1/83 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW + + G PY + ++ G R P+ A + ++Q CW DP RP F Sbjct: 1103 LLWEIFSLGASPYPGVQINEEFCQRLKDGTRMRAPELATPAIRHIMQSCWSGDPKARPAF 1162 Query: 413 SEILEALKKIAEEVGDEHDGKHK 345 S+++E L + + G + + + + Sbjct: 1163 SDLVEILGDLLQGGGWQEEEEER 1185
>TIE1_HUMAN (P35590) Tyrosine-protein kinase receptor Tie-1 precursor (EC| 2.7.10.1) Length = 1138 Score = 40.4 bits (93), Expect = 0.004 Identities = 24/72 (33%), Positives = 40/72 (55%), Gaps = 1/72 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW +++ G PY T + + Q G R P+N ++ EL+++CW+ P ERP F Sbjct: 1042 LLWEIVSLGGTPYCGMTCAELYEKLPQ-GYRMEQPRNCDDEVYELMRQCWRDRPYERPPF 1100 Query: 413 SEILEALKKIAE 378 ++I L ++ E Sbjct: 1101 AQIALQLGRMLE 1112
>VGFR2_RAT (O08775) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Protein-tyrosine kinase receptor flk-1) (Fetal liver kinase 1) Length = 1343 Score = 40.4 bits (93), Expect = 0.004 Identities = 23/81 (28%), Positives = 40/81 (49%), Gaps = 1/81 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW + + G PY + +++G R P ++ + + CW +DP +RP F Sbjct: 1090 LLWEIFSLGASPYPGVKIDEKFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHEDPNQRPAF 1149 Query: 413 SEILEALKKIAEEVGDEHDGK 351 SE++E L + + + DGK Sbjct: 1150 SELVEHLGNLL-QANAQQDGK 1169
>TIE1_MOUSE (Q06806) Tyrosine-protein kinase receptor Tie-1 precursor (EC| 2.7.10.1) Length = 1134 Score = 40.4 bits (93), Expect = 0.004 Identities = 24/72 (33%), Positives = 40/72 (55%), Gaps = 1/72 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW +++ G PY T + + Q G R P+N ++ EL+++CW+ P ERP F Sbjct: 1038 LLWEIVSLGGTPYCGMTCAELYEKLPQ-GYRMEQPRNCDDEVYELMRQCWRDRPYERPPF 1096 Query: 413 SEILEALKKIAE 378 ++I L ++ E Sbjct: 1097 AQIALQLGRMLE 1108
>MUSK_HUMAN (O15146) Muscle, skeletal receptor tyrosine protein kinase precursor| (EC 2.7.10.1) (Muscle-specific tyrosine protein kinase receptor) (Muscle-specific kinase receptor) (MuSK) Length = 869 Score = 40.4 bits (93), Expect = 0.004 Identities = 19/71 (26%), Positives = 37/71 (52%) Frame = -1 Query: 590 LLWXLLTGKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDFS 411 +LW + + + Y + + V+ G + P+N +L L++ CW + PA+RP F+ Sbjct: 791 VLWEIFSYGLQPYYGMAHEEVIYYVRDGNILSCPENCPVELYNLMRLCWSKLPADRPSFT 850 Query: 410 EILEALKKIAE 378 I L+++ E Sbjct: 851 SIHRILERMCE 861
>FYN_XENLA (P13406) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 536 Score = 40.4 bits (93), Expect = 0.004 Identities = 22/60 (36%), Positives = 34/60 (56%), Gaps = 1/60 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LL L+T G++PY + + V++G R P++ L EL+ CW++DP ERP F Sbjct: 454 LLTELVTKGRVPYPGMNNREV-LEQVERGYRMPCPQDCPISLHELMLNCWKKDPEERPTF 512
>FGFR3_MOUSE (Q61851) Fibroblast growth factor receptor 3 precursor (EC| 2.7.10.1) (FGFR-3) (Heparin-binding growth factor receptor) Length = 801 Score = 40.4 bits (93), Expect = 0.004 Identities = 20/70 (28%), Positives = 38/70 (54%), Gaps = 1/70 (1%) Frame = -1 Query: 590 LLWXLLTGKIPYEY-XTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW + T P Y P++ ++++G R P + L ++++CW P++RP F Sbjct: 677 LLWEIFTPGGPSPYPGIPVEELFKLLKEGHRMDKPASCTHDLYMIMRECWHAVPSQRPTF 736 Query: 413 SEILEALKKI 384 +++E L +I Sbjct: 737 KQLVEDLDRI 746
>EPHA3_MOUSE (P29319) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ETK1) (MEK4) Length = 983 Score = 40.4 bits (93), Expect = 0.004 Identities = 23/75 (30%), Positives = 38/75 (50%), Gaps = 1/75 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 +LW +++ G+ PY + Q + V + R P + A L +L+ CWQ+D RP F Sbjct: 813 VLWEVMSYGERPYSQMSN-QDVIKAVDERYRLPPPMDCPAALYQLMLDCWQKDRNNRPKF 871 Query: 413 SEILEALKKIAEEVG 369 +I+ L K+ G Sbjct: 872 EQIVSILDKLIRNPG 886
>SEA_AVIET (P23049) Tyrosine-protein kinase transforming protein SEA (EC| 2.7.10.2) Length = 370 Score = 40.4 bits (93), Expect = 0.004 Identities = 25/78 (32%), Positives = 38/78 (48%), Gaps = 1/78 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 L+W LLT G PY P A ++ +G R P+ L ++ CW P ERP F Sbjct: 254 LMWELLTRGASPYPEVDPYDMARYLL-RGRRLPQPQPCPDTLYGVMLSCWAPTPEERPSF 312 Query: 413 SEILEALKKIAEEVGDEH 360 S ++ L+++ + EH Sbjct: 313 SGLVCELERVLASLEGEH 330
>EPB1B_XENLA (Q91736) Ephrin type-B receptor 1-B (EC 2.7.10.1) (Tyrosine-protein| kinase receptor XELK) (Fragment) Length = 902 Score = 40.4 bits (93), Expect = 0.004 Identities = 21/70 (30%), Positives = 38/70 (54%), Gaps = 1/70 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 ++W +++ G+ PY + Q + +++ R P + A L +L+ CWQ+D RP F Sbjct: 731 VMWEVMSYGERPY-WDMSNQDVINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRF 789 Query: 413 SEILEALKKI 384 EI+ L K+ Sbjct: 790 GEIVNTLDKM 799
>VGFR3_RAT (Q91ZT1) Vascular endothelial growth factor receptor 3 precursor (EC| 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4) Length = 1363 Score = 40.0 bits (92), Expect = 0.005 Identities = 22/75 (29%), Positives = 36/75 (48%), Gaps = 1/75 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW + + G PY + ++ G R P+ A + ++Q CW DP RP F Sbjct: 1103 LLWEIFSLGASPYPGVQINEEFCQRLKDGTRMRAPELATPAIRHIMQSCWSGDPKARPAF 1162 Query: 413 SEILEALKKIAEEVG 369 S+++E L + + G Sbjct: 1163 SDLVEILGDLLQGGG 1177
>KIN16_CAEEL (P34892) Receptor-like tyrosine-protein kinase kin-16 precursor (EC| 2.7.10.1) Length = 495 Score = 40.0 bits (92), Expect = 0.005 Identities = 18/57 (31%), Positives = 31/57 (54%) Frame = -1 Query: 569 GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDFSEILE 399 G++PY P + + G R P++ H +L +L++ CW + P RP+FS +E Sbjct: 397 GQLPYP-DVPSERIYEYMHSGRRCPQPQHCHVELYDLMKLCWHEKPELRPNFSNCVE 452
>BMX_HUMAN (P51813) Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2)| (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38) Length = 675 Score = 40.0 bits (92), Expect = 0.005 Identities = 23/78 (29%), Positives = 42/78 (53%), Gaps = 1/78 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 L+W + + GK PY+ Q + V Q G R P A + +++ CW + P +RP F Sbjct: 601 LMWEVFSLGKQPYDLYDNSQVVLKVSQ-GHRLYRPHLASDTIYQIMYSCWHELPEKRPTF 659 Query: 413 SEILEALKKIAEEVGDEH 360 ++L +++ + E+ D+H Sbjct: 660 QQLLSSIEPLREK--DKH 675
>FGFR1_RAT (Q04589) Basic fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) (FGFR-1) (bFGF-R) (MFR) Length = 822 Score = 40.0 bits (92), Expect = 0.005 Identities = 19/69 (27%), Positives = 36/69 (52%) Frame = -1 Query: 590 LLWXLLTGKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDFS 411 LLW + T P++ ++++G R P N +L +++ CW P++RP F Sbjct: 689 LLWEIFTLGGSPNPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWNAVPSQRPTFK 748 Query: 410 EILEALKKI 384 +++E L +I Sbjct: 749 QLVEDLDRI 757
>YES_XENLA (P10936) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 536 Score = 40.0 bits (92), Expect = 0.005 Identities = 20/60 (33%), Positives = 32/60 (53%) Frame = -1 Query: 569 GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDFSEILEALK 390 G++PY + + V++G R P+ L EL++ CW++DP ERP F I L+ Sbjct: 462 GRVPYPGMVNREV-LEQVERGYRMPCPQRCPESLHELMKLCWKKDPDERPTFEYIQSFLE 520
>FYN_HUMAN (P06241) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) (Protooncogene Syn) (SLK) Length = 536 Score = 40.0 bits (92), Expect = 0.005 Identities = 23/68 (33%), Positives = 37/68 (54%), Gaps = 1/68 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LL L+T G++PY + + V++G R P++ L EL+ CW++DP ERP F Sbjct: 454 LLTELVTKGRVPYPGMNNREV-LEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTF 512 Query: 413 SEILEALK 390 + L+ Sbjct: 513 EYLQSFLE 520
>FPS_AVISP (P00541) Tyrosine-protein kinase transforming protein Fps (EC| 2.7.10.2) Length = 533 Score = 40.0 bits (92), Expect = 0.005 Identities = 21/67 (31%), Positives = 33/67 (49%), Gaps = 1/67 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW + G +PY + Q + Q G+R P+ + L+Q+CW+ DP RP F Sbjct: 460 LLWEAFSLGAVPYANLSNQQTREAIEQ-GVRLEPPEQCPEDVYRLMQRCWEYDPRRRPSF 518 Query: 413 SEILEAL 393 + + L Sbjct: 519 GAVHQDL 525
>EPHA4_MOUSE (Q03137) Ephrin type-A receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor SEK) (MPK-3) Length = 986 Score = 40.0 bits (92), Expect = 0.005 Identities = 19/70 (27%), Positives = 40/70 (57%), Gaps = 1/70 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 ++W +++ G+ PY + Q + +++G R P + L +L+ CWQ++ ++RP F Sbjct: 813 VMWEVMSYGERPY-WDMSNQDVIKAIEEGYRLPPPMDCPIALHQLMLDCWQKERSDRPKF 871 Query: 413 SEILEALKKI 384 +I+ L K+ Sbjct: 872 GQIVNMLDKL 881
>EPHA4_HUMAN (P54764) Ephrin type-A receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8) Length = 986 Score = 40.0 bits (92), Expect = 0.005 Identities = 19/70 (27%), Positives = 40/70 (57%), Gaps = 1/70 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 ++W +++ G+ PY + Q + +++G R P + L +L+ CWQ++ ++RP F Sbjct: 813 VMWEVMSYGERPY-WDMSNQDVIKAIEEGYRLPPPMDCPIALHQLMLDCWQKERSDRPKF 871 Query: 413 SEILEALKKI 384 +I+ L K+ Sbjct: 872 GQIVNMLDKL 881
>EPHA4_CHICK (Q07496) Ephrin type-A receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor CEK8) Length = 986 Score = 40.0 bits (92), Expect = 0.005 Identities = 19/70 (27%), Positives = 40/70 (57%), Gaps = 1/70 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 ++W +++ G+ PY + Q + +++G R P + L +L+ CWQ++ ++RP F Sbjct: 813 VMWEVMSYGERPY-WDMSNQDVIKAIEEGYRLPPPMDCPIALHQLMLDCWQKERSDRPKF 871 Query: 413 SEILEALKKI 384 +I+ L K+ Sbjct: 872 GQIVNMLDKL 881
>EPA4A_XENLA (Q91845) Ephrin type-A receptor 4-A precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor SEK-1) (xSEK-1) Length = 986 Score = 40.0 bits (92), Expect = 0.005 Identities = 19/70 (27%), Positives = 40/70 (57%), Gaps = 1/70 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 ++W +++ G+ PY + Q + +++G R P + L +L+ CWQ++ ++RP F Sbjct: 812 VMWEVMSYGERPY-WDMSNQDVIKAIEEGYRLPPPMDCPIALHQLMLDCWQKERSDRPKF 870 Query: 413 SEILEALKKI 384 +I+ L K+ Sbjct: 871 GQIVSMLDKL 880
>XMRK_XIPMA (P13388) Melanoma receptor tyrosine-protein kinase precursor (EC| 2.7.10.1) Length = 1167 Score = 40.0 bits (92), Expect = 0.005 Identities = 21/72 (29%), Positives = 37/72 (51%), Gaps = 1/72 (1%) Frame = -1 Query: 587 LWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDFS 411 +W L+T G PY+ P + V++ G R P ++ ++ KCW DP+ RP F Sbjct: 902 VWELMTFGSKPYD-GIPAKEIASVLENGERLPQPPICTIEVYMIILKCWMIDPSSRPRFR 960 Query: 410 EILEALKKIAEE 375 E++ ++A + Sbjct: 961 ELVGEFSQMARD 972
>INSR_AEDAE (Q93105) Insulin-like receptor precursor (EC 2.7.10.1) (MIR)| [Contains: Insulin-like receptor alpha chain; Insulin-like receptor beta chain] Length = 1390 Score = 40.0 bits (92), Expect = 0.005 Identities = 23/67 (34%), Positives = 33/67 (49%), Gaps = 1/67 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 +LW + T PY+ T Q V+ G+ P+N L L+++CWQ P RP F Sbjct: 1228 VLWEMATLASQPYQGLTNDQVLRYVIDGGVMER-PENCPDNLYNLMRRCWQHRPTARPTF 1286 Query: 413 SEILEAL 393 EI+ L Sbjct: 1287 MEIISEL 1293
>FYN_MOUSE (P39688) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 533 Score = 39.7 bits (91), Expect = 0.007 Identities = 22/60 (36%), Positives = 34/60 (56%), Gaps = 1/60 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LL L+T G++PY + + V++G R P++ L EL+ CW++DP ERP F Sbjct: 451 LLTELVTKGRVPYPGMNNREV-LEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTF 509
>FYN_CHICK (Q05876) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 533 Score = 39.7 bits (91), Expect = 0.007 Identities = 22/60 (36%), Positives = 34/60 (56%), Gaps = 1/60 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LL L+T G++PY + + V++G R P++ L EL+ CW++DP ERP F Sbjct: 451 LLTELVTKGRVPYPGMNNREV-LEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTF 509
>YES_HUMAN (P07947) Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2)| (p61-Yes) (c-Yes) Length = 542 Score = 39.7 bits (91), Expect = 0.007 Identities = 20/60 (33%), Positives = 31/60 (51%) Frame = -1 Query: 569 GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDFSEILEALK 390 G++PY + + V++G R P+ L EL+ CW++DP ERP F I L+ Sbjct: 468 GRVPYPGMVNREV-LEQVERGYRMPCPQGCPESLHELMNLCWKKDPDERPTFEYIQSFLE 526
>FPS_FUJSV (P00530) Tyrosine-protein kinase transforming protein FPS (EC| 2.7.10.2) Length = 873 Score = 39.7 bits (91), Expect = 0.007 Identities = 21/67 (31%), Positives = 33/67 (49%), Gaps = 1/67 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW + G +PY + Q + Q G+R P+ + L+Q+CW+ DP RP F Sbjct: 800 LLWEAFSLGAVPYANLSNQQTREAIEQ-GVRLEPPEQCPEDVYRLMQRCWEYDPHRRPSF 858 Query: 413 SEILEAL 393 + + L Sbjct: 859 GAVHQDL 865
>INSR_RAT (P15127) Insulin receptor precursor (EC 2.7.10.1) (IR) [Contains:| Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1383 Score = 39.7 bits (91), Expect = 0.007 Identities = 25/69 (36%), Positives = 38/69 (55%), Gaps = 2/69 (2%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKG-LRPTIPKNAHAKLTELLQKCWQQDPAERPD 417 +LW + + + PY+ + Q V+ G L P P N +LT+L++ CWQ +P RP Sbjct: 1226 VLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDP--PDNCPERLTDLMRMCWQFNPKMRPT 1283 Query: 416 FSEILEALK 390 F EI+ LK Sbjct: 1284 FLEIVNLLK 1292
>YES_MOUSE (Q04736) Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2)| (p61-Yes) (c-Yes) Length = 540 Score = 39.7 bits (91), Expect = 0.007 Identities = 20/60 (33%), Positives = 31/60 (51%) Frame = -1 Query: 569 GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDFSEILEALK 390 G++PY + + V++G R P+ L EL+ CW++DP ERP F I L+ Sbjct: 466 GRVPYPGMVNREV-LEQVERGYRMPCPQGCPESLHELMNLCWKKDPDERPTFEYIQSFLE 524
>RIPK2_HUMAN (O43353) Receptor-interacting serine/threonine-protein kinase 2 (EC| 2.7.11.1) (RIP-like-interacting CLARP kinase) (Receptor-interacting protein 2) (RIP-2) (CARD-containing interleukin-1 beta-converting enzyme-associated kinase) (CARD-containi Length = 540 Score = 39.7 bits (91), Expect = 0.007 Identities = 26/77 (33%), Positives = 40/77 (51%), Gaps = 8/77 (10%) Frame = -1 Query: 590 LLWXLLTGKIPYEYXT-PLQAAVGVVQKGLRPTIPKNA-------HAKLTELLQKCWQQD 435 + W +L+ K P+E T PLQ V Q G RP I + + A++ L++ W Q+ Sbjct: 218 ITWEVLSRKQPFEDVTNPLQIMYSVSQ-GHRPVINEESLPYDIPHRARMISLIESGWAQN 276 Query: 434 PAERPDFSEILEALKKI 384 P ERP F + L L+ + Sbjct: 277 PDERPSFLKCLIELEPV 293
>ERBB_AVIEU (P11273) Tyrosine-protein kinase transforming protein erbB (EC| 2.7.10.1) Length = 540 Score = 39.7 bits (91), Expect = 0.007 Identities = 22/72 (30%), Positives = 34/72 (47%), Gaps = 1/72 (1%) Frame = -1 Query: 587 LWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDFS 411 +W L+T G PY+ P V++KG R P + ++ KCW D RP F Sbjct: 324 VWELMTFGSKPYD-GIPASEISSVLEKGERLPQPPICTIDVYMIMVKCWMSDADSRPKFR 382 Query: 410 EILEALKKIAEE 375 E++ K+A + Sbjct: 383 ELIAEFSKMARD 394
>RIPK1_HUMAN (Q13546) Receptor-interacting serine/threonine-protein kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein) Length = 671 Score = 39.7 bits (91), Expect = 0.007 Identities = 25/93 (26%), Positives = 42/93 (45%), Gaps = 8/93 (8%) Frame = -1 Query: 590 LLWXLLTGKIPYEYXTPLQAAVGVVQKGLRPT---IPKNAHAKLTELLQKCWQQDPAERP 420 +LW + K PYE Q + ++ G RP I + ++ L++ CW+ +P RP Sbjct: 217 VLWAIFANKEPYENAICEQQLIMCIKSGNRPDVDDITEYCPREIISLMKLCWEANPEARP 276 Query: 419 DFSEILEA-----LKKIAEEVGDEHDGKHKDKS 336 F I E L ++ E V ++ K+ S Sbjct: 277 TFPGIEEKFRPFYLSQLEESVEEDVKSLKKEYS 309
>VGFR2_BRARE (Q8AXB3) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Receptor tyrosine kinase flk-1) Length = 1302 Score = 39.7 bits (91), Expect = 0.007 Identities = 20/82 (24%), Positives = 44/82 (53%), Gaps = 1/82 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 L+W + + G PY + +++G R P+ + +++ + + CW +P++RP F Sbjct: 1069 LMWEIFSLGASPYPGLHIDEEFCCRLKEGTRMKAPEYSSSEIYQTMLDCWHGEPSQRPTF 1128 Query: 413 SEILEALKKIAEEVGDEHDGKH 348 +E++E L + + + +GKH Sbjct: 1129 TELVERLGDLL-QASVQQEGKH 1149
>EPHA8_HUMAN (P29322) Ephrin type-A receptor 8 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase) (HEK3) Length = 1005 Score = 39.7 bits (91), Expect = 0.007 Identities = 22/67 (32%), Positives = 36/67 (53%), Gaps = 1/67 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 ++W +L G+ PY T + + V++G R P L +L+ CW +D A+RP F Sbjct: 827 VMWEVLAYGERPYWNMTN-RDVISSVEEGYRLPAPMGCPHALHQLMLDCWHKDRAQRPRF 885 Query: 413 SEILEAL 393 S+I+ L Sbjct: 886 SQIVSVL 892
>FGFR2_DROME (Q09147) Fibroblast growth factor receptor homolog 2 precursor (EC| 2.7.10.1) (Protein breathless) (dFGF-R1) Length = 1052 Score = 39.7 bits (91), Expect = 0.007 Identities = 20/86 (23%), Positives = 39/86 (45%), Gaps = 1/86 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW ++T G PY + + + G R P + ++++CW + RP F Sbjct: 930 LLWEIMTYGDQPYPHILSAEELYSYLITGQRMEKPAKCSLNIYVVMRQCWHFESCARPTF 989 Query: 413 SEILEALKKIAEEVGDEHDGKHKDKS 336 +E++E+ I ++ + + D S Sbjct: 990 AELVESFDGILQQASSNPNDAYLDLS 1015
>RYK_AVIR3 (P33497) Tyrosine-protein kinase transforming protein RYK (EC| 2.7.10.1) Length = 442 Score = 39.7 bits (91), Expect = 0.007 Identities = 16/46 (34%), Positives = 29/46 (63%) Frame = -1 Query: 509 GLRPTIPKNAHAKLTELLQKCWQQDPAERPDFSEILEALKKIAEEV 372 G R P+N +L +++ CW+ +PA+RP FS++ L+K+ E + Sbjct: 274 GQRLKKPENCLDELYDIMSSCWRAEPADRPTFSQLKVHLEKLLESL 319
>YES_CANFA (Q28923) Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2)| (p61-Yes) (c-Yes) Length = 538 Score = 39.7 bits (91), Expect = 0.007 Identities = 20/60 (33%), Positives = 31/60 (51%) Frame = -1 Query: 569 GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDFSEILEALK 390 G++PY + + V++G R P+ L EL+ CW++DP ERP F I L+ Sbjct: 464 GRVPYPGMVNREV-LEQVERGYRMPCPQGCPESLHELMNLCWKKDPDERPTFEYIQSFLE 522
>INSR_MOUSE (P15208) Insulin receptor precursor (EC 2.7.10.1) (IR) [Contains:| Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1372 Score = 39.7 bits (91), Expect = 0.007 Identities = 25/69 (36%), Positives = 38/69 (55%), Gaps = 2/69 (2%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKG-LRPTIPKNAHAKLTELLQKCWQQDPAERPD 417 +LW + + + PY+ + Q V+ G L P P N +LT+L++ CWQ +P RP Sbjct: 1215 VLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDP--PDNCPERLTDLMRMCWQFNPKMRPT 1272 Query: 416 FSEILEALK 390 F EI+ LK Sbjct: 1273 FLEIVNLLK 1281
>RIPK1_MOUSE (Q60855) Receptor-interacting serine/threonine-protein kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein) Length = 656 Score = 39.7 bits (91), Expect = 0.007 Identities = 20/70 (28%), Positives = 34/70 (48%), Gaps = 3/70 (4%) Frame = -1 Query: 590 LLWXLLTGKIPYEYXTPLQAAVGVVQKGLRPTIPKNAH---AKLTELLQKCWQQDPAERP 420 +LW + K PYE + V ++ G RP + + ++ L+++CWQ P +RP Sbjct: 218 VLWAIFAKKEPYENVICTEQFVICIKSGNRPNVEEILEYCPREIISLMERCWQAIPEDRP 277 Query: 419 DFSEILEALK 390 F I E + Sbjct: 278 TFLGIEEEFR 287
>YES_XIPHE (P27447) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 543 Score = 39.3 bits (90), Expect = 0.009 Identities = 22/68 (32%), Positives = 37/68 (54%), Gaps = 1/68 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LL L+T G++PY + + V +G R P+ L E++++CW+++P ERP F Sbjct: 461 LLTELVTKGRVPYPGMVNREV-LEQVDRGYRMPCPQGCPESLHEMMRQCWKKEPDERPTF 519 Query: 413 SEILEALK 390 I L+ Sbjct: 520 EYIQSFLE 527
>EPHA8_MOUSE (O09127) Ephrin type-A receptor 8 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase) Length = 1004 Score = 39.3 bits (90), Expect = 0.009 Identities = 21/67 (31%), Positives = 35/67 (52%), Gaps = 1/67 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 ++W +L G+ PY T Q + V++G R P L +L+ CW +D A+RP F Sbjct: 826 VMWEVLAYGERPYWNMTN-QDVISSVEEGYRLPAPMGCPRALHQLMLDCWHKDRAQRPRF 884 Query: 413 SEILEAL 393 + ++ L Sbjct: 885 AHVVSVL 891
>PGFRA_MOUSE (P26618) Alpha platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-alpha) Length = 1089 Score = 39.3 bits (90), Expect = 0.009 Identities = 22/70 (31%), Positives = 36/70 (51%), Gaps = 4/70 (5%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW + + G PY ++ G R P +A +++ E++ +CW +P +RP F Sbjct: 884 LLWEIFSLGGTPYPGMMVDSTFYNKIKSGYRMAKPDHATSEVYEIMVQCWNSEPEKRPSF 943 Query: 413 ---SEILEAL 393 SEI+E L Sbjct: 944 YHLSEIVENL 953
>CSF1R_FELCA (P13369) Macrophage colony-stimulating factor 1 receptor precursor| (CSF-1-R) (EC 2.7.10.1) (Fms proto-oncogene) (c-fms) Length = 980 Score = 39.3 bits (90), Expect = 0.009 Identities = 22/73 (30%), Positives = 34/73 (46%), Gaps = 1/73 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW + + G PY +V+ G + P A + ++Q CW +P RP F Sbjct: 842 LLWEIFSLGLNPYPGILVNSKFYKLVKDGYQMAQPAFAPKNIYSIMQACWALEPTRRPTF 901 Query: 413 SEILEALKKIAEE 375 +I L+K A+E Sbjct: 902 QQICSLLQKQAQE 914
>KFMS_FSVMD (P00545) Tyrosine-protein kinase transforming protein fms (EC| 2.7.10.1) Length = 978 Score = 39.3 bits (90), Expect = 0.009 Identities = 22/73 (30%), Positives = 34/73 (46%), Gaps = 1/73 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW + + G PY +V+ G + P A + ++Q CW +P RP F Sbjct: 876 LLWEIFSLGLNPYPGILVNSKFYKLVKDGYQMAQPAFAPKNIYSIMQACWALEPTRRPTF 935 Query: 413 SEILEALKKIAEE 375 +I L+K A+E Sbjct: 936 QQICSLLQKQAQE 948
>INSR_XENLA (Q9PVZ4) Insulin receptor precursor (EC 2.7.10.1) (IR) (Xe-InsR)| (XTK-1b) [Contains: Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1362 Score = 39.3 bits (90), Expect = 0.009 Identities = 16/34 (47%), Positives = 22/34 (64%) Frame = -1 Query: 491 PKNAHAKLTELLQKCWQQDPAERPDFSEILEALK 390 P+N +L L+Q CWQ +P RP F EI++ LK Sbjct: 1247 PENCPPRLHSLMQMCWQYNPKMRPTFLEIIDMLK 1280
>MET_PONPY (Q2IBD8) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1390 Score = 39.3 bits (90), Expect = 0.009 Identities = 26/78 (33%), Positives = 35/78 (44%), Gaps = 1/78 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW L+T G PY V ++Q G R P+ L E++ KCW RP F Sbjct: 1272 LLWELMTRGAPPYPDVNTFDITVYLLQ-GRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSF 1330 Query: 413 SEILEALKKIAEEVGDEH 360 SE++ + I EH Sbjct: 1331 SELVSRISAIFSTFIGEH 1348
>MET_PANTR (Q2QLF1) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1390 Score = 39.3 bits (90), Expect = 0.009 Identities = 26/78 (33%), Positives = 35/78 (44%), Gaps = 1/78 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW L+T G PY V ++Q G R P+ L E++ KCW RP F Sbjct: 1272 LLWELMTRGAPPYPDVNTFDITVYLLQ-GRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSF 1330 Query: 413 SEILEALKKIAEEVGDEH 360 SE++ + I EH Sbjct: 1331 SELVSRISAIFSTFIGEH 1348
>MET_MOUSE (P16056) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1379 Score = 39.3 bits (90), Expect = 0.009 Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 1/78 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW L+T G PY + ++Q G R P+ L E++ KCW RP F Sbjct: 1270 LLWELMTRGAPPYPDVNTFDITIYLLQ-GRRLLQPEYCPDALYEVMLKCWHPKAEMRPSF 1328 Query: 413 SEILEALKKIAEEVGDEH 360 SE++ + I EH Sbjct: 1329 SELVSRISSIFSTFIGEH 1346
>EPHA6_HUMAN (Q9UF33) Ephrin type-A receptor 6 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2) Length = 1035 Score = 39.3 bits (90), Expect = 0.009 Identities = 20/70 (28%), Positives = 39/70 (55%), Gaps = 1/70 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 ++W +++ G+ PY + Q + +++G R P A L +L+ CWQ++ RP F Sbjct: 864 VMWEVMSYGERPY-WEMSNQDVILSIEEGYRLPAPMGCPASLHQLMLHCWQKERNHRPKF 922 Query: 413 SEILEALKKI 384 ++I+ L K+ Sbjct: 923 TDIVSFLDKL 932
>MET_CALMO (Q2QLC0) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1381 Score = 39.3 bits (90), Expect = 0.009 Identities = 26/78 (33%), Positives = 35/78 (44%), Gaps = 1/78 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW L+T G PY V ++Q G R P+ L E++ KCW RP F Sbjct: 1272 LLWELMTRGAPPYPDVNTFDITVYLLQ-GRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSF 1330 Query: 413 SEILEALKKIAEEVGDEH 360 SE++ + I EH Sbjct: 1331 SELVSRISAIFSTFIGEH 1348
>MET_CALJA (Q2QLG5) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1381 Score = 39.3 bits (90), Expect = 0.009 Identities = 26/78 (33%), Positives = 35/78 (44%), Gaps = 1/78 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW L+T G PY V ++Q G R P+ L E++ KCW RP F Sbjct: 1272 LLWELMTRGAPPYPDVNTFDITVYLLQ-GRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSF 1330 Query: 413 SEILEALKKIAEEVGDEH 360 SE++ + I EH Sbjct: 1331 SELVSRISAIFSTFIGEH 1348
>HCK_HUMAN (P08631) Tyrosine-protein kinase HCK (EC 2.7.10.2)| (p59-HCK/p60-HCK) (Hemopoietic cell kinase) Length = 525 Score = 39.3 bits (90), Expect = 0.009 Identities = 21/67 (31%), Positives = 36/67 (53%), Gaps = 1/67 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LL ++T G+IPY + + + +++G R P+N +L ++ +CW+ P ERP F Sbjct: 445 LLMEIVTYGRIPYPGMSNPEV-IRALERGYRMPRPENCPEELYNIMMRCWKNRPEERPTF 503 Query: 413 SEILEAL 393 I L Sbjct: 504 EYIQSVL 510
>FES_MOUSE (P16879) Proto-oncogene tyrosine-protein kinase Fes/Fps (EC| 2.7.10.2) (C-Fes) Length = 820 Score = 39.3 bits (90), Expect = 0.009 Identities = 24/70 (34%), Positives = 34/70 (48%), Gaps = 1/70 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW + G PY T Q V+KG R P+ + L+++CW +P +RP F Sbjct: 747 LLWETFSLGASPYPNLTNQQTRE-FVEKGHRLPCPELCPDAVFRLMEQCWAYEPGQRPSF 805 Query: 413 SEILEALKKI 384 S I + L I Sbjct: 806 SIICQELHSI 815
>PGFRA_RAT (P20786) Alpha platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-alpha) Length = 1088 Score = 39.3 bits (90), Expect = 0.009 Identities = 22/70 (31%), Positives = 36/70 (51%), Gaps = 4/70 (5%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW + + G PY ++ G R P +A +++ E++ +CW +P +RP F Sbjct: 883 LLWEIFSLGGTPYPGMMVDSTFYNKIKSGYRMAKPDHATSEVYEIMVQCWNSEPEKRPSF 942 Query: 413 ---SEILEAL 393 SEI+E L Sbjct: 943 YHLSEIVENL 952
>MET_OTOGA (Q2QLH6) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1382 Score = 39.3 bits (90), Expect = 0.009 Identities = 26/78 (33%), Positives = 35/78 (44%), Gaps = 1/78 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW L+T G PY V ++Q G R P+ L E++ KCW RP F Sbjct: 1273 LLWELMTRGAPPYPDVNTFDITVYLLQ-GRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSF 1331 Query: 413 SEILEALKKIAEEVGDEH 360 SE++ + I EH Sbjct: 1332 SELVSRISAIFSTFIGEH 1349
>MET_MICMU (Q2QL89) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1382 Score = 39.3 bits (90), Expect = 0.009 Identities = 26/78 (33%), Positives = 35/78 (44%), Gaps = 1/78 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW L+T G PY V ++Q G R P+ L E++ KCW RP F Sbjct: 1273 LLWELMTRGAPPYPDVNTFDITVYLLQ-GRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSF 1331 Query: 413 SEILEALKKIAEEVGDEH 360 SE++ + I EH Sbjct: 1332 SELVSRISAIFSTFIGEH 1349
>MERTK_RAT (P57097) Proto-oncogene tyrosine-protein kinase MER precursor (EC| 2.7.10.1) (C-mer) (Receptor tyrosine kinase MerTK) Length = 994 Score = 39.3 bits (90), Expect = 0.009 Identities = 18/51 (35%), Positives = 28/51 (54%) Frame = -1 Query: 509 GLRPTIPKNAHAKLTELLQKCWQQDPAERPDFSEILEALKKIAEEVGDEHD 357 G R P++ L E++ CW DP +RP FS + L+K++E + D D Sbjct: 811 GHRLKQPEDCLDDLYEIMYSCWSADPLDRPTFSVLRLQLEKLSESLPDAQD 861
>HCK_MACFA (Q95M30) Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK)| (Hemopoietic cell kinase) Length = 503 Score = 39.3 bits (90), Expect = 0.009 Identities = 21/67 (31%), Positives = 36/67 (53%), Gaps = 1/67 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LL ++T G+IPY + + + +++G R P+N +L ++ +CW+ P ERP F Sbjct: 423 LLMEIVTYGRIPYPGMSNPEV-IRALERGYRMPRPENCPEELYNIMMRCWKNRPEERPTF 481 Query: 413 SEILEAL 393 I L Sbjct: 482 EYIQSVL 488
>CSK_MOUSE (P41241) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| (Protein-tyrosine kinase MPK-2) (p50CSK) Length = 450 Score = 38.9 bits (89), Expect = 0.011 Identities = 22/70 (31%), Positives = 37/70 (52%), Gaps = 1/70 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW + + G++PY PL+ V V+KG + P + ++++ C D A RP F Sbjct: 375 LLWEIYSFGRVPYP-RIPLKDVVPRVEKGYKMDAPDGCPPAVYDVMKNCSHLDAATRPTF 433 Query: 413 SEILEALKKI 384 ++ E L+ I Sbjct: 434 LQLREQLEHI 443
>SRK4_SPOLA (P42690) Tyrosine-protein kinase isoform SRK4 (EC 2.7.10.2)| Length = 506 Score = 38.9 bits (89), Expect = 0.011 Identities = 26/84 (30%), Positives = 42/84 (50%), Gaps = 1/84 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 +L+ ++T G+ PY T Q + +Q+ R P KL ++ CW++DPA RP F Sbjct: 424 VLYEVITYGRFPYPGMTNAQV-LEQIQQSYRMPRPMGCPEKLYAIMMDCWREDPASRPTF 482 Query: 413 SEILEALKKIAEEVGDEHDGKHKD 342 + L++ GD D +KD Sbjct: 483 ETLSWQLEEFF-TTGD--DAGYKD 503
>MUSK_RAT (Q62838) Muscle, skeletal receptor tyrosine protein kinase precursor| (EC 2.7.10.1) (Muscle-specific kinase receptor) (MuSK) Length = 868 Score = 38.9 bits (89), Expect = 0.011 Identities = 19/71 (26%), Positives = 35/71 (49%) Frame = -1 Query: 590 LLWXLLTGKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDFS 411 +LW + + + Y + + V+ G P+N +L L++ CW + PA+RP F Sbjct: 790 VLWEIFSYGLQPYYGMAHEEVIYYVRDGNILACPENCPLELYNLMRLCWSKLPADRPSFC 849 Query: 410 EILEALKKIAE 378 I L+++ E Sbjct: 850 SIHRILQRMCE 860
>MUSK_MOUSE (Q61006) Muscle, skeletal receptor tyrosine protein kinase precursor| (EC 2.7.10.1) (Muscle-specific kinase receptor) (MuSK) Length = 868 Score = 38.9 bits (89), Expect = 0.011 Identities = 19/71 (26%), Positives = 35/71 (49%) Frame = -1 Query: 590 LLWXLLTGKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDFS 411 +LW + + + Y + + V+ G P+N +L L++ CW + PA+RP F Sbjct: 790 VLWEIFSYGLQPYYGMAHEEVIYYVRDGNILACPENCPLELYNLMRLCWSKLPADRPSFC 849 Query: 410 EILEALKKIAE 378 I L+++ E Sbjct: 850 SIHRILQRMCE 860
>MUSK_CHICK (Q8AXY6) Muscle, skeletal receptor tyrosine protein kinase precursor| (EC 2.7.10.1) (Muscle-specific tyrosine protein kinase receptor) (Muscle-specific kinase receptor) (MuSK) Length = 947 Score = 38.9 bits (89), Expect = 0.011 Identities = 22/72 (30%), Positives = 38/72 (52%), Gaps = 1/72 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 +LW + + G PY Y + + V+ G + P N +L L++ CW + PA+RP F Sbjct: 869 VLWEIFSYGMQPY-YGMAHEEVIYYVRDGNILSCPDNCPLELYNLMRLCWSKLPADRPSF 927 Query: 413 SEILEALKKIAE 378 + I L+++ E Sbjct: 928 ASIHRILERMYE 939
>INSRR_HUMAN (P14616) Insulin receptor-related protein precursor (EC 2.7.10.1)| (IRR) (IR-related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain] Length = 1297 Score = 38.9 bits (89), Expect = 0.011 Identities = 20/69 (28%), Positives = 40/69 (57%), Gaps = 1/69 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 +LW ++T + PY+ + Q V+ G+ + + +L EL+ +CWQ +P RP F Sbjct: 1181 VLWEIVTLAEQPYQGLSNEQVLKFVMDGGVLEEL-EGCPLQLQELMSRCWQPNPRLRPSF 1239 Query: 413 SEILEALKK 387 + IL+++++ Sbjct: 1240 THILDSIQE 1248
>CSF1R_HUMAN (P07333) Macrophage colony-stimulating factor 1 receptor precursor| (CSF-1-R) (EC 2.7.10.1) (Fms proto-oncogene) (c-fms) (CD115 antigen) Length = 972 Score = 38.9 bits (89), Expect = 0.011 Identities = 23/79 (29%), Positives = 36/79 (45%), Gaps = 1/79 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW + + G PY +V+ G + P A + ++Q CW +P RP F Sbjct: 844 LLWEIFSLGLNPYPGILVNSKFYKLVKDGYQMAQPAFAPKNIYSIMQACWALEPTHRPTF 903 Query: 413 SEILEALKKIAEEVGDEHD 357 +I L++ A+E E D Sbjct: 904 QQICSFLQEQAQEDRRERD 922
>7LESS_DROME (P13368) Protein sevenless (EC 2.7.10.1)| Length = 2554 Score = 38.9 bits (89), Expect = 0.011 Identities = 25/74 (33%), Positives = 35/74 (47%), Gaps = 1/74 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 L W +LT G+ PY + + V++G R P KL LL CW+ DP ERP F Sbjct: 2416 LCWEILTLGQQPYAARNNFEV-LAHVKEGGRLQQPPMCTEKLYSLLLLCWRTDPWERPSF 2474 Query: 413 SEILEALKKIAEEV 372 L I+ ++ Sbjct: 2475 RRCYNTLHAISTDL 2488
>FES_HUMAN (P07332) Proto-oncogene tyrosine-protein kinase Fes/Fps (EC| 2.7.10.2) (C-Fes) Length = 822 Score = 38.9 bits (89), Expect = 0.011 Identities = 23/70 (32%), Positives = 35/70 (50%), Gaps = 1/70 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW + G PY + Q V+KG R P+ + L+++CW +P +RP F Sbjct: 749 LLWETFSLGASPYPNLSNQQTRE-FVEKGGRLPCPELCPDAVFRLMEQCWAYEPGQRPSF 807 Query: 413 SEILEALKKI 384 S I + L+ I Sbjct: 808 STIYQELQSI 817
>VGFR2_HUMAN (P35968) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Kinase insert domain receptor) (Protein-tyrosine kinase receptor Flk-1) (CD309 antigen) Length = 1356 Score = 38.9 bits (89), Expect = 0.011 Identities = 22/81 (27%), Positives = 40/81 (49%), Gaps = 1/81 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW + + G PY + +++G R P ++ + + CW +P++RP F Sbjct: 1094 LLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTF 1153 Query: 413 SEILEALKKIAEEVGDEHDGK 351 SE++E L + + + DGK Sbjct: 1154 SELVEHLGNLL-QANAQQDGK 1173
>MET_HORSE (Q2QLA9) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1381 Score = 38.9 bits (89), Expect = 0.011 Identities = 26/78 (33%), Positives = 35/78 (44%), Gaps = 1/78 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW L+T G PY V ++Q G R P+ L E++ KCW RP F Sbjct: 1272 LLWELMTRGAPPYPDVNTFDITVYLLQ-GRRLLQPEYCPDPLYEVMLKCWHPKAELRPSF 1330 Query: 413 SEILEALKKIAEEVGDEH 360 SE++ + I EH Sbjct: 1331 SELVSRISAIFSTFIGEH 1348
>FES_FELCA (P14238) Proto-oncogene tyrosine-protein kinase FES/FPS (EC| 2.7.10.2) (C-FES) Length = 820 Score = 38.9 bits (89), Expect = 0.011 Identities = 23/70 (32%), Positives = 35/70 (50%), Gaps = 1/70 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW + G PY + Q V+KG R P+ + L+++CW +P +RP F Sbjct: 747 LLWETFSLGASPYPNLSNQQTRE-FVEKGGRLPCPELCPDAVFRLMEQCWAYEPGQRPSF 805 Query: 413 SEILEALKKI 384 S I + L+ I Sbjct: 806 SAIYQELQSI 815
>MERTK_MOUSE (Q60805) Proto-oncogene tyrosine-protein kinase MER precursor (EC| 2.7.10.1) (C-mer) (Receptor tyrosine kinase MerTK) Length = 994 Score = 38.9 bits (89), Expect = 0.011 Identities = 17/51 (33%), Positives = 29/51 (56%) Frame = -1 Query: 509 GLRPTIPKNAHAKLTELLQKCWQQDPAERPDFSEILEALKKIAEEVGDEHD 357 G R P++ +L +++ CW DP +RP FS + L+K++E + D D Sbjct: 811 GHRLKQPEDCLDELYDIMYSCWSADPLDRPTFSVLRLQLEKLSESLPDAQD 861
>FES_FSVGA (P00542) Tyrosine-protein kinase transforming protein Fes (EC| 2.7.10.2) Length = 609 Score = 38.9 bits (89), Expect = 0.011 Identities = 23/70 (32%), Positives = 35/70 (50%), Gaps = 1/70 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW + G PY + Q V+KG R P+ + L+++CW +P +RP F Sbjct: 536 LLWETFSLGASPYPNLSNQQTRE-FVEKGGRLPCPELCPDAVFRLMEQCWAYEPGQRPSF 594 Query: 413 SEILEALKKI 384 S I + L+ I Sbjct: 595 SAIYQELQSI 604
>SRC2_XENLA (P13116) Tyrosine-protein kinase Src-2 (EC 2.7.10.2) (p60-Src-2)| Length = 531 Score = 38.9 bits (89), Expect = 0.011 Identities = 24/66 (36%), Positives = 37/66 (56%), Gaps = 1/66 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LL L T G++PY + + V++G R P + L +L+ +CW++DP ERP F Sbjct: 449 LLTELTTKGRVPYPGMVNREV-LDQVERGYRMPCPPDCPESLHDLMFQCWRKDPEERPTF 507 Query: 413 SEILEA 396 E L+A Sbjct: 508 -EYLQA 512
>SRC1_XENLA (P13115) Tyrosine-protein kinase Src-1 (EC 2.7.10.2) (p60-Src-1)| Length = 531 Score = 38.9 bits (89), Expect = 0.011 Identities = 24/66 (36%), Positives = 37/66 (56%), Gaps = 1/66 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LL L T G++PY + + V++G R P + L +L+ +CW++DP ERP F Sbjct: 449 LLTELTTKGRVPYPGMVNREV-LDQVERGYRMPCPPDCPESLHDLMFQCWRKDPEERPTF 507 Query: 413 SEILEA 396 E L+A Sbjct: 508 -EYLQA 512
>LCK_HUMAN (P06239) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell-specific protein-tyrosine kinase) Length = 508 Score = 38.9 bits (89), Expect = 0.011 Identities = 23/83 (27%), Positives = 46/83 (55%), Gaps = 1/83 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LL ++T G+IPY T + + +++G R P N +L +L++ CW++ P +RP F Sbjct: 428 LLTEIVTHGRIPYPGMTNPEV-IQNLERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTF 486 Query: 413 SEILEALKKIAEEVGDEHDGKHK 345 + L+ + E+ +G+++ Sbjct: 487 ----DYLRSVLEDFFTATEGQYQ 505
>ABL1_CAEEL (P03949) Tyrosine-protein kinase abl-1 (EC 2.7.10.2)| Length = 1224 Score = 38.5 bits (88), Expect = 0.015 Identities = 20/63 (31%), Positives = 31/63 (49%), Gaps = 1/63 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW + T G PY L G+++ G R P+ + L+ +CW P++RP F Sbjct: 497 LLWEIATYGMAPYP-GVELSNVYGLLENGFRMDGPQGCPPSVYRLMLQCWNWSPSDRPRF 555 Query: 413 SEI 405 +I Sbjct: 556 RDI 558
>SRC_AVIS2 (P15054) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 586 Score = 38.5 bits (88), Expect = 0.015 Identities = 24/66 (36%), Positives = 36/66 (54%), Gaps = 1/66 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LL L T G++PY + + V++G R P L +L+ +CW++DP ERP F Sbjct: 450 LLTELTTKGRVPYPGMVNREV-LDQVERGYRMPCPPECPESLHDLMCQCWRKDPEERPTF 508 Query: 413 SEILEA 396 E L+A Sbjct: 509 -EYLQA 513
>SRC_AVIST (P14085) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 556 Score = 38.5 bits (88), Expect = 0.015 Identities = 24/66 (36%), Positives = 36/66 (54%), Gaps = 1/66 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LL L T G++PY + + V++G R P L +L+ +CW++DP ERP F Sbjct: 450 LLTELTTKGRVPYPGMVNREV-LDQVERGYRMPCPPECPESLHDLMCQCWRKDPEERPTF 508 Query: 413 SEILEA 396 E L+A Sbjct: 509 -EYLQA 513
>VGFR3_HUMAN (P35916) Vascular endothelial growth factor receptor 3 precursor (EC| 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4) Length = 1298 Score = 38.5 bits (88), Expect = 0.015 Identities = 22/75 (29%), Positives = 35/75 (46%), Gaps = 1/75 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW + + G PY + ++ G R P+ A + ++ CW DP RP F Sbjct: 1103 LLWEIFSLGASPYPGVQINEEFCQRLRDGTRMRAPELATPAIRRIMLNCWSGDPKARPAF 1162 Query: 413 SEILEALKKIAEEVG 369 SE++E L + + G Sbjct: 1163 SELVEILGDLLQGRG 1177
>EPHB2_HUMAN (P29323) Ephrin type-B receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen) Length = 1055 Score = 38.5 bits (88), Expect = 0.015 Identities = 20/70 (28%), Positives = 38/70 (54%), Gaps = 1/70 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 ++W +++ G+ PY T Q + +++ R P + + L +L+ CWQ+D RP F Sbjct: 815 VMWEVMSYGERPYWDMTN-QDVINAIEQDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKF 873 Query: 413 SEILEALKKI 384 +I+ L K+ Sbjct: 874 GQIVNTLDKM 883
>M3K7_DROME (Q9V3Q6) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (TGF-beta-activated kinase 1) (dTAK1) Length = 678 Score = 38.5 bits (88), Expect = 0.015 Identities = 17/72 (23%), Positives = 35/72 (48%) Frame = -1 Query: 590 LLWXLLTGKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDFS 411 +LW +L+ K P++ + KG RP + ++ +L+ CW+ P +RP Sbjct: 202 VLWEVLSRKQPFKGIDNAYTIQWKIYKGERPPLLTTCPKRIEDLMTACWKTVPEDRPSMQ 261 Query: 410 EILEALKKIAEE 375 I+ + +I ++ Sbjct: 262 YIVGVMHEIVKD 273
>HTK7_HYDAT (Q25197) Putative insulin-like peptide receptor precursor (EC| 2.7.10.1) Length = 1477 Score = 38.5 bits (88), Expect = 0.015 Identities = 25/77 (32%), Positives = 36/77 (46%), Gaps = 1/77 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 +LW + T PY+ T Q V+ G P+ +L E + CW +DP RP F Sbjct: 1241 VLWEICTLASQPYQGKTNEQVLNFVLSNG-HLDYPEGCDYQLREFMSLCWHRDPKMRPSF 1299 Query: 413 SEILEALKKIAEEVGDE 363 EI+ L+ EV D+ Sbjct: 1300 LEIVHVLE---NEVDDD 1313
>ERBB_ALV (P00534) Tyrosine-protein kinase transforming protein erbB (EC| 2.7.10.1) Length = 634 Score = 38.5 bits (88), Expect = 0.015 Identities = 22/72 (30%), Positives = 34/72 (47%), Gaps = 1/72 (1%) Frame = -1 Query: 587 LWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDFS 411 +W L+T G PY+ P V++KG R P + ++ KCW D RP F Sbjct: 324 VWELMTFGSKPYD-GIPASEISSVLEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFR 382 Query: 410 EILEALKKIAEE 375 E++ K+A + Sbjct: 383 ELIAEFSKMARD 394
>ERBB_AVIER (P00535) Tyrosine-protein kinase transforming protein erbB (EC| 2.7.10.1) Length = 604 Score = 38.5 bits (88), Expect = 0.015 Identities = 22/72 (30%), Positives = 34/72 (47%), Gaps = 1/72 (1%) Frame = -1 Query: 587 LWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDFS 411 +W L+T G PY+ P V++KG R P + ++ KCW D RP F Sbjct: 324 VWELMTFGSKPYD-GIPASEISSVLEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFR 382 Query: 410 EILEALKKIAEE 375 E++ K+A + Sbjct: 383 ELIAEFSKMARD 394
>VGFR2_COTJA (P52583) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Endothelial kinase receptor EK1) (Quek 1) (Quek1) Length = 1348 Score = 38.5 bits (88), Expect = 0.015 Identities = 23/81 (28%), Positives = 38/81 (46%), Gaps = 1/81 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW + + G PY + +++G R P ++ + + CW DP +RP F Sbjct: 1087 LLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGDPKQRPTF 1146 Query: 413 SEILEALKKIAEEVGDEHDGK 351 SE++E L + + DGK Sbjct: 1147 SELVEHLGNLL-QANVRQDGK 1166
>PGFRA_XENLA (P26619) Alpha platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-alpha) Length = 1087 Score = 38.5 bits (88), Expect = 0.015 Identities = 21/70 (30%), Positives = 36/70 (51%), Gaps = 4/70 (5%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW + + G PY ++ G R P +A ++ +++ KCW +P +RP F Sbjct: 884 LLWEIFSLGGTPYPGMIVDSTFYNKIKSGYRMAKPDHATHEVYDIMVKCWNSEPEKRPSF 943 Query: 413 ---SEILEAL 393 S+I+E+L Sbjct: 944 RHLSDIVESL 953
>EPHB4_MOUSE (P54761) Ephrin type-B receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor MDK-2) (Developmental kinase 2) (Tyrosine kinase MYK-1) Length = 987 Score = 38.5 bits (88), Expect = 0.015 Identities = 19/70 (27%), Positives = 38/70 (54%), Gaps = 1/70 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 ++W +++ G+ PY + Q + +++ R P + L +L+ CWQ+D RP F Sbjct: 809 VMWEVMSFGERPY-WDMSNQDVINAIEQDYRLPPPPDCPTSLHQLMLDCWQKDRNARPRF 867 Query: 413 SEILEALKKI 384 +++ AL K+ Sbjct: 868 PQVVSALDKM 877
>EPHB4_HUMAN (P54760) Ephrin type-B receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor HTK) Length = 987 Score = 38.5 bits (88), Expect = 0.015 Identities = 19/70 (27%), Positives = 38/70 (54%), Gaps = 1/70 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 ++W +++ G+ PY + Q + +++ R P + L +L+ CWQ+D RP F Sbjct: 809 VMWEVMSFGERPY-WDMSNQDVINAIEQDYRLPPPPDCPTSLHQLMLDCWQKDRNARPRF 867 Query: 413 SEILEALKKI 384 +++ AL K+ Sbjct: 868 PQVVSALDKM 877
>MET_PIG (Q2QLE0) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1381 Score = 38.5 bits (88), Expect = 0.015 Identities = 26/78 (33%), Positives = 35/78 (44%), Gaps = 1/78 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW L+T G PY V ++Q G R P+ L E++ KCW RP F Sbjct: 1272 LLWELMTRGAPPYPDVNTFDITVYLLQ-GRRLLQPEYCPDPLYEVMLKCWHPRAELRPSF 1330 Query: 413 SEILEALKKIAEEVGDEH 360 SE++ + I EH Sbjct: 1331 SELVSRISAIFSTFIGEH 1348
>MET_CANFA (Q75ZY9) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1382 Score = 38.5 bits (88), Expect = 0.015 Identities = 26/78 (33%), Positives = 35/78 (44%), Gaps = 1/78 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW L+T G PY V ++Q G R P+ L E++ KCW RP F Sbjct: 1273 LLWELMTRGAPPYPDVNTFDITVYLLQ-GRRLLQPEYCPDPLYEVMLKCWHPRAELRPSF 1331 Query: 413 SEILEALKKIAEEVGDEH 360 SE++ + I EH Sbjct: 1332 SELVSRISAIFSTFIGEH 1349
>SRC_AVISS (P14084) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 567 Score = 38.5 bits (88), Expect = 0.015 Identities = 24/66 (36%), Positives = 36/66 (54%), Gaps = 1/66 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LL L T G++PY + + V++G R P L +L+ +CW++DP ERP F Sbjct: 450 LLTELTTKGRVPYPGMVNREV-LDQVERGYRMPCPPECPESLHDLMCQCWRKDPEERPTF 508 Query: 413 SEILEA 396 E L+A Sbjct: 509 -EYLQA 513
>EPHB2_MOUSE (P54763) Ephrin type-B receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3) Length = 994 Score = 38.5 bits (88), Expect = 0.015 Identities = 20/70 (28%), Positives = 38/70 (54%), Gaps = 1/70 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 ++W +++ G+ PY T Q + +++ R P + + L +L+ CWQ+D RP F Sbjct: 823 VMWEVMSYGERPYWDMTN-QDVINAIEQDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKF 881 Query: 413 SEILEALKKI 384 +I+ L K+ Sbjct: 882 GQIVNTLDKM 891
>SRC_CHICK (P00523) Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2)| (p60-Src) (c-Src) (pp60c-src) Length = 532 Score = 38.5 bits (88), Expect = 0.015 Identities = 24/66 (36%), Positives = 36/66 (54%), Gaps = 1/66 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LL L T G++PY + + V++G R P L +L+ +CW++DP ERP F Sbjct: 450 LLTELTTKGRVPYPGMVNREV-LDQVERGYRMPCPPECPESLHDLMCQCWRKDPEERPTF 508 Query: 413 SEILEA 396 E L+A Sbjct: 509 -EYLQA 513
>TIE1_BOVIN (Q06805) Tyrosine-protein kinase receptor Tie-1 precursor (EC| 2.7.10.1) Length = 1136 Score = 38.1 bits (87), Expect = 0.019 Identities = 23/72 (31%), Positives = 39/72 (54%), Gaps = 1/72 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 LLW +++ G PY T + + Q R P+N ++ EL+++CW+ P ERP F Sbjct: 1040 LLWEIVSLGGTPYCGMTCAELYEKLPQ-AYRMEQPRNCDDEVYELMRQCWRDRPYERPPF 1098 Query: 413 SEILEALKKIAE 378 ++I L ++ E Sbjct: 1099 AQIALQLGRMLE 1110
>SRK1_SPOLA (P42686) Tyrosine-protein kinase isoform SRK1 (EC 2.7.10.2)| Length = 505 Score = 38.1 bits (87), Expect = 0.019 Identities = 20/75 (26%), Positives = 38/75 (50%), Gaps = 1/75 (1%) Frame = -1 Query: 590 LLWXLLT-GKIPYEYXTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAERPDF 414 +L+ ++T G+ PY T + + +Q+ R P N + +++ CW++DPA RP F Sbjct: 424 VLYEIITYGRFPYPGMTNPEV-LEKIQQNYRMPCPANCPKQFHDIMLDCWREDPASRPTF 482 Query: 413 SEILEALKKIAEEVG 369 + L++ G Sbjct: 483 ETLQWQLEEFFNSEG 497 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 78,304,586 Number of Sequences: 219361 Number of extensions: 1493927 Number of successful extensions: 4545 Number of sequences better than 10.0: 466 Number of HSP's better than 10.0 without gapping: 4381 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4528 length of database: 80,573,946 effective HSP length: 106 effective length of database: 57,321,680 effective search space used: 5158951200 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
