ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | rbags4o22 |
|---|---|
| Clone Library Name | barley_pub |
>PHOT1_ARATH (O48963) Phototropin-1 (EC 2.7.11.1) (Non-phototropic hypocotyl| protein 1) (Root phototropism protein 1) Length = 996 Score = 167 bits (423), Expect = 2e-41 Identities = 76/123 (61%), Positives = 97/123 (78%), Gaps = 2/123 (1%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWWALGIL+YEMLYGYTPFRGKTRQ+TF N+L KD++FPASI SL +QLI+RLL RDP Sbjct: 874 DWWALGILMYEMLYGYTPFRGKTRQKTFTNVLQKDLKFPASIPASLQVKQLIFRLLQRDP 933 Query: 404 ANRMGSYEGSNEIKQHPFFRGINWALVRGTAPPKLDAPLFSKDV--GKGMGDAAAADNGT 231 R+G +EG+NE+KQH FF+GINWAL+R T PP+L+ P+FS + G+ + D D T Sbjct: 934 KKRLGCFEGANEVKQHSFFKGINWALIRCTNPPELETPIFSGEAENGEKVVDPELEDLQT 993 Query: 230 DMF 222 ++F Sbjct: 994 NVF 996
>PHOT2_ARATH (P93025) Phototropin-2 (EC 2.7.11.1) (Defective in chloroplast| avoidance protein 1) (Non phototropic hypocotyl 1-like protein 1) (NPH1-like 1) (AtKin7) Length = 915 Score = 161 bits (408), Expect = 1e-39 Identities = 78/117 (66%), Positives = 90/117 (76%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWWALGILLYEMLYG TPFRGK RQ+TFANILHKD+ FP+SI VSL RQLI LL+RDP Sbjct: 786 DWWALGILLYEMLYGRTPFRGKNRQKTFANILHKDLTFPSSIPVSLVGRQLINTLLNRDP 845 Query: 404 ANRMGSYEGSNEIKQHPFFRGINWALVRGTAPPKLDAPLFSKDVGKGMGDAAAADNG 234 ++R+GS G+NEIKQH FFRGINW L+RG +PP LDAPL + D D+G Sbjct: 846 SSRLGSKGGANEIKQHAFFRGINWPLIRGMSPPPLDAPLSIIEKDPNAKDIKWEDDG 902
>KPK7_ARATH (Q05999) Putative serine/threonine-protein kinase PK7 (EC 2.7.11.1)| Length = 578 Score = 111 bits (277), Expect = 2e-24 Identities = 49/103 (47%), Positives = 69/103 (66%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW GI LYE+L+G TPFRG + T N++ + +RFP +VS AR LI LL ++P Sbjct: 438 DWWTFGIFLYELLFGITPFRGGDNRATLFNVVGQPLRFPEHPNVSFAARDLIRGLLVKEP 497 Query: 404 ANRMGSYEGSNEIKQHPFFRGINWALVRGTAPPKLDAPLFSKD 276 +R+ G+ EIKQHPFF+ +NWAL+R T+PP++ P+ D Sbjct: 498 QHRLAYRRGATEIKQHPFFQSVNWALIRCTSPPQIPQPVKPMD 540
>KAD5_SCHPO (Q09831) Probable serine/threonine-protein kinase C4G8.05 (EC| 2.7.11.1) Length = 566 Score = 110 bits (276), Expect = 2e-24 Identities = 51/96 (53%), Positives = 67/96 (69%), Gaps = 3/96 (3%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPA---SISVSLPARQLIYRLLH 414 DWW LGIL YEMLY TPF+GK R TF+NILHKD+ FP + S+S + LI +LL Sbjct: 404 DWWTLGILFYEMLYATTPFKGKNRNMTFSNILHKDVIFPEYADAPSISSLCKNLIRKLLV 463 Query: 413 RDPANRMGSYEGSNEIKQHPFFRGINWALVRGTAPP 306 +D +R+GS G+ ++K HPFF+ + WAL+R T PP Sbjct: 464 KDENDRLGSQAGAADVKLHPFFKNVQWALLRHTEPP 499
>G11A_ORYSA (P47997) Protein kinase G11A (EC 2.7.11.1)| Length = 589 Score = 110 bits (275), Expect = 3e-24 Identities = 48/99 (48%), Positives = 66/99 (66%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW GI LYE+L+G TPF+G + T N++ + +RFP VS AR LI LL ++P Sbjct: 455 DWWTFGIFLYELLFGKTPFKGSGNRATLFNVIGQPLRFPEYPVVSFSARDLIRGLLVKEP 514 Query: 404 ANRMGSYEGSNEIKQHPFFRGINWALVRGTAPPKLDAPL 288 R+G G+ EIKQHPFF G+NWAL+R +PP++ P+ Sbjct: 515 QQRLGCKRGATEIKQHPFFEGVNWALIRCASPPEVPRPV 553
>KPK1_PHAVU (P15792) Protein kinase PVPK-1 (EC 2.7.11.1)| Length = 609 Score = 110 bits (274), Expect = 4e-24 Identities = 50/110 (45%), Positives = 71/110 (64%), Gaps = 5/110 (4%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW GI LYE+L+G TPF+G + T N++ + +RFP S +VS AR LI LL ++P Sbjct: 487 DWWTFGIFLYELLFGRTPFKGSANRATLFNVIGQPLRFPESPTVSFAARDLIRGLLVKEP 546 Query: 404 ANRMGSYEGSNEIKQHPFFRGINWALVRGTAPPK-----LDAPLFSKDVG 270 +R+ G+ EIKQHPFF+ +NWAL+R PP+ ++ P KD+G Sbjct: 547 QHRLAYRRGATEIKQHPFFQNVNWALIRCATPPEVPRQVINLPQTEKDLG 596
>KIN82_YEAST (P25341) Probable serine/threonine-protein kinase KIN82 (EC| 2.7.11.1) Length = 720 Score = 108 bits (271), Expect = 9e-24 Identities = 47/97 (48%), Positives = 67/97 (69%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW LGIL+YEML+G TPF+G TF+NIL KD++FP VS + LI +LL+++ Sbjct: 524 DWWTLGILIYEMLFGCTPFKGDNSNETFSNILTKDVKFPHDKEVSKNCKDLIKKLLNKNE 583 Query: 404 ANRMGSYEGSNEIKQHPFFRGINWALVRGTAPPKLDA 294 A R+GS G+ +IK+HPFF+ + W+ +R PP + A Sbjct: 584 AKRLGSKSGAADIKRHPFFKKVQWSFLRNQDPPLIPA 620
>NRC2_NEUCR (O42626) Serine/threonine-protein kinase nrc-2 (EC 2.7.11.1)| (Nonrepressible conidiation protein 2) Length = 623 Score = 107 bits (266), Expect = 3e-23 Identities = 51/96 (53%), Positives = 65/96 (67%), Gaps = 3/96 (3%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFP---ASISVSLPARQLIYRLLH 414 DWW LGIL+YEMLYG TPF+GK R TFANIL +DI FP + +S + LI +LL Sbjct: 451 DWWTLGILIYEMLYGTTPFKGKNRNATFANILREDIPFPDHAGAPQISNLCKSLIRKLLI 510 Query: 413 RDPANRMGSYEGSNEIKQHPFFRGINWALVRGTAPP 306 +D R+G+ G+++IK HPFFR WAL+R PP Sbjct: 511 KDENRRLGARAGASDIKTHPFFRTTQWALIRHMKPP 546
>KN8R_YEAST (P53739) Probable serine/threonine-protein kinase YNR047W (EC| 2.7.11.1) Length = 893 Score = 104 bits (259), Expect = 2e-22 Identities = 44/103 (42%), Positives = 69/103 (66%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW LGIL+YEML+G+TPF+G TF NIL ++ FP + +S + LI +LL ++ Sbjct: 699 DWWTLGILIYEMLFGFTPFKGDNTNETFTNILKNEVSFPNNNEISRTCKDLIKKLLTKNE 758 Query: 404 ANRMGSYEGSNEIKQHPFFRGINWALVRGTAPPKLDAPLFSKD 276 + R+G G+ ++K+HPFF+ + W+L+R PP + P+ S+D Sbjct: 759 SKRLGCKMGAADVKKHPFFKKVQWSLLRNQEPPLI--PVLSED 799
>CEK1_SCHPO (P38938) Serine/threonine-protein kinase cek1 (EC 2.7.11.1)| Length = 1338 Score = 90.5 bits (223), Expect = 3e-18 Identities = 45/105 (42%), Positives = 64/105 (60%), Gaps = 2/105 (1%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASI--SVSLPARQLIYRLLHR 411 DWW+LG +++E L+GY PF +T + F NIL + I +PA + + S A LI RLL Sbjct: 879 DWWSLGCVVFEFLFGYPPFNAETPDQVFQNILARRINWPAEVFTAESSVALDLIDRLLCM 938 Query: 410 DPANRMGSYEGSNEIKQHPFFRGINWALVRGTAPPKLDAPLFSKD 276 +PANR+G+ G EIK HPFF+ +NW + PP + P +D Sbjct: 939 NPANRLGA-NGVEEIKAHPFFKSVNWDTILEEDPPFVPKPFSPED 982
>CBK1_YEAST (P53894) Serine/threonine-protein kinase CBK1 (EC 2.7.11.1) (Cell| wall biosynthesis kinase) Length = 756 Score = 85.9 bits (211), Expect = 8e-17 Identities = 42/96 (43%), Positives = 61/96 (63%), Gaps = 3/96 (3%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILH--KDIRFPASISVSLPARQLIYRLL-H 414 DWW+LG ++YE L G+ PF +T Q T+ I++ + ++FP I +S A LI RLL H Sbjct: 593 DWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQFPDDIHISYEAEDLIRRLLTH 652 Query: 413 RDPANRMGSYEGSNEIKQHPFFRGINWALVRGTAPP 306 D R+G + G++EIK HPFFRG++W +R P Sbjct: 653 AD--QRLGRHGGADEIKSHPFFRGVDWNTIRQVEAP 686
>CBK1_KLULA (P31034) Serine/threonine-protein kinase CBK1 (EC 2.7.11.1)| Length = 718 Score = 84.3 bits (207), Expect = 2e-16 Identities = 40/95 (42%), Positives = 59/95 (62%), Gaps = 2/95 (2%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILH--KDIRFPASISVSLPARQLIYRLLHR 411 DWW+LG ++YE L G+ PF +T Q T+ I++ + ++FP I +S A LI RLL Sbjct: 552 DWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQFPDDIHISYEAEDLIRRLLTH 611 Query: 410 DPANRMGSYEGSNEIKQHPFFRGINWALVRGTAPP 306 NR+G + G++EIK HPFF G++W +R P Sbjct: 612 S-ENRLGRHGGADEIKAHPFFSGVDWNTIRQVEAP 645
>CBK1_ASHGO (Q754N7) Serine/threonine-protein kinase CBK1 (EC 2.7.11.1)| Length = 719 Score = 83.2 bits (204), Expect = 5e-16 Identities = 43/96 (44%), Positives = 60/96 (62%), Gaps = 3/96 (3%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILH--KDIRFPASISVSLPARQLIYRLL-H 414 DWW+LG ++YE L G+ PF +T Q T+ I++ + + FP I +S A LI RLL H Sbjct: 553 DWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLVFPDDIHISYEAEDLIRRLLSH 612 Query: 413 RDPANRMGSYEGSNEIKQHPFFRGINWALVRGTAPP 306 D R+G + G+NEIK HPFFRG++W +R P Sbjct: 613 AD--ERLGRH-GANEIKNHPFFRGVDWETIRQVGAP 645
>CBK1_CANGA (Q6FP74) Serine/threonine-protein kinase CBK1 (EC 2.7.11.1)| Length = 773 Score = 83.2 bits (204), Expect = 5e-16 Identities = 39/95 (41%), Positives = 58/95 (61%), Gaps = 2/95 (2%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILH--KDIRFPASISVSLPARQLIYRLLHR 411 DWW+LG ++YE L G+ PF +T Q T+ I++ + ++FP + +S A LI RLL Sbjct: 607 DWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQFPEDVHISYEAEDLIRRLLTH 666 Query: 410 DPANRMGSYEGSNEIKQHPFFRGINWALVRGTAPP 306 R+G G++EIK HPFFRG++W +R P Sbjct: 667 S-NQRLGRQGGADEIKSHPFFRGVDWNTIRQVEAP 700
>CBK1_DEBHA (Q6BLJ9) Serine/threonine-protein kinase CBK1 (EC 2.7.11.1)| Length = 716 Score = 82.8 bits (203), Expect = 7e-16 Identities = 41/104 (39%), Positives = 64/104 (61%), Gaps = 2/104 (1%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILH--KDIRFPASISVSLPARQLIYRLLHR 411 DWW+LG +++E L G+ PF +T T+ IL+ + ++ P I +S + LI +LL Sbjct: 555 DWWSLGAIMFECLIGWPPFCSETPHETYRKILNWQETLQIPDDIHLSPESEDLIRKLL-T 613 Query: 410 DPANRMGSYEGSNEIKQHPFFRGINWALVRGTAPPKLDAPLFSK 279 + NR+G Y G++E+K HPFFRG++W +R K+DAP K Sbjct: 614 NAENRLGRYNGADELKLHPFFRGVDWDTIR-----KVDAPFIPK 652
>SCK2_SCHPO (Q10364) Serine/threonine-protein kinase sck2 (EC 2.7.11.1)| Length = 646 Score = 82.4 bits (202), Expect = 9e-16 Identities = 37/84 (44%), Positives = 58/84 (69%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 D+W+LG+LLYEM G++PF Q+ + NI+ +RFP + +S+ AR LI LL+R+P Sbjct: 450 DFWSLGVLLYEMTCGWSPFYADNTQQLYKNIVFGKVRFPRGL-LSVEARDLIKLLLNRNP 508 Query: 404 ANRMGSYEGSNEIKQHPFFRGINW 333 +R+G++ E+ +HPFF GI+W Sbjct: 509 KHRLGAHGDVEEVMKHPFFDGIDW 532
>PKN1_MOUSE (P70268) Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protein| kinase C-like 1) (Protein-kinase C-related kinase 1) (Protein kinase C-like PKN) (Serine-threonine protein kinase N) Length = 946 Score = 80.5 bits (197), Expect = 3e-15 Identities = 40/96 (41%), Positives = 59/96 (61%), Gaps = 3/96 (3%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW LG+LLYEML G +PF G + F +I++ ++R+P +S A ++ RLL R+P Sbjct: 801 DWWGLGVLLYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSAE--AIGIMRRLLRRNP 858 Query: 404 ANRMGSYE-GSNEIKQHPFFRGINW--ALVRGTAPP 306 R+GS E + ++K+ PFFR + W L R PP Sbjct: 859 ERRLGSTERDAEDVKKQPFFRSLGWDVLLARRLPPP 894
>SGK3_HUMAN (Q96BR1) Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 3) (Serum/glucocorticoid-regulated kinase-like) Length = 496 Score = 80.5 bits (197), Expect = 3e-15 Identities = 43/104 (41%), Positives = 58/104 (55%), Gaps = 1/104 (0%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW LG +LYEMLYG PF + + NILHK + VSL A ++ LL +D Sbjct: 343 DWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKPLSLRP--GVSLTAWSILEELLEKDR 400 Query: 404 ANRMGSYEGSNEIKQHPFFRGINWA-LVRGTAPPKLDAPLFSKD 276 NR+G+ E EI+ HPFF ++WA LV+ PP + + D Sbjct: 401 QNRLGAKEDFLEIQNHPFFESLSWADLVQKKIPPPFNPNVAGPD 444
>PKN2_HUMAN (Q16513) Serine/threonine-protein kinase N2 (EC 2.7.11.13) (Protein| kinase C-like 2) (Protein-kinase C-related kinase 2) Length = 984 Score = 80.5 bits (197), Expect = 3e-15 Identities = 36/86 (41%), Positives = 58/86 (67%), Gaps = 1/86 (1%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW LG+L+YEML G +PF G + F +I++ ++R+P +S A ++ RLL R+P Sbjct: 839 DWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTE--AISIMRRLLRRNP 896 Query: 404 ANRMGSYE-GSNEIKQHPFFRGINWA 330 R+G+ E + ++K+HPFFR I+W+ Sbjct: 897 ERRLGASEKDAEDVKKHPFFRLIDWS 922
>PKN1_HUMAN (Q16512) Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protein| kinase C-like 1) (Protein-kinase C-related kinase 1) (Protein kinase C-like PKN) (Serine-threonine protein kinase N) (Protein kinase PKN-alpha) Length = 942 Score = 80.1 bits (196), Expect = 4e-15 Identities = 40/95 (42%), Positives = 60/95 (63%), Gaps = 2/95 (2%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW LG+LLYEML G +PF G + F +I++ ++R+P +S A ++ RLL R+P Sbjct: 797 DWWGLGVLLYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSAE--AIGIMRRLLRRNP 854 Query: 404 ANRMGSYE-GSNEIKQHPFFRGINW-ALVRGTAPP 306 R+GS E + ++K+ PFFR + W AL+ PP Sbjct: 855 ERRLGSSERDAEDVKKQPFFRTLGWEALLARRLPP 889
>KAPA_YEAST (P06244) cAMP-dependent protein kinase type 1 (EC 2.7.11.11) (PKA| 1) (CDC25-suppressing protein kinase) (PK-25) Length = 397 Score = 80.1 bits (196), Expect = 4e-15 Identities = 41/118 (34%), Positives = 67/118 (56%), Gaps = 3/118 (2%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW+ GIL+YEML GYTPF +T+ IL+ ++RFP + + + L+ RL+ RD Sbjct: 264 DWWSFGILIYEMLAGYTPFYDSNTMKTYEKILNAELRFPPFFNEDV--KDLLSRLITRDL 321 Query: 404 ANRMGSYE-GSNEIKQHPFFRGINW--ALVRGTAPPKLDAPLFSKDVGKGMGDAAAAD 240 + R+G+ + G+ ++K HP+F+ + W L R P + + +G GD + D Sbjct: 322 SQRLGNLQNGTEDVKNHPWFKEVVWEKLLSRNIETP------YEPPIQQGQGDTSQFD 373
>KAPC_YEAST (P05986) cAMP-dependent protein kinase type 3 (EC 2.7.11.11) (PKA| 3) Length = 398 Score = 80.1 bits (196), Expect = 4e-15 Identities = 41/118 (34%), Positives = 66/118 (55%), Gaps = 3/118 (2%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW+ G+L+YEML GYTPF +T+ NIL+ +++FP A+ L+ +L+ RD Sbjct: 265 DWWSFGVLIYEMLAGYTPFYNSNTMKTYENILNAELKFPPFFHPD--AQDLLKKLITRDL 322 Query: 404 ANRMGSYE-GSNEIKQHPFFRGINW--ALVRGTAPPKLDAPLFSKDVGKGMGDAAAAD 240 + R+G+ + GS ++K HP+F + W L R P + + +G GD + D Sbjct: 323 SERLGNLQNGSEDVKNHPWFNEVIWEKLLARYIETP------YEPPIQQGQGDTSQFD 374
>MAST3_HUMAN (O60307) Microtubule-associated serine/threonine-protein kinase 3| (EC 2.7.11.1) Length = 1309 Score = 79.7 bits (195), Expect = 6e-15 Identities = 42/101 (41%), Positives = 65/101 (64%), Gaps = 4/101 (3%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFP-ASISVSLPARQLIYRLLHRD 408 DWWA+G++LYE L G PF G T + F ++ +I +P ++ A+ LI RLL + Sbjct: 562 DWWAMGVVLYEFLVGCVPFFGDTPEELFGQVVSDEIMWPEGDEALPADAQDLITRLLRQS 621 Query: 407 PANRMGSYEGSNEIKQHPFFRGINWA-LVRGTAP--PKLDA 294 P +R+G+ G++E+KQHPFF ++WA L+R A P+L+A Sbjct: 622 PLDRLGT-GGTHEVKQHPFFLALDWAGLLRHKAEFVPQLEA 661
>ST38L_HUMAN (Q9Y2H1) Serine/threonine-protein kinase 38-like (EC 2.7.11.1)| (NDR2 protein kinase) (Nuclear Dbf2-related kinase 2) Length = 464 Score = 79.3 bits (194), Expect = 7e-15 Identities = 38/90 (42%), Positives = 57/90 (63%), Gaps = 2/90 (2%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILH--KDIRFPASISVSLPARQLIYRLLHR 411 DWW+LG+++YEML GY PF +T Q T+ +++ + + FP + +S A+ LI R Sbjct: 305 DWWSLGVIMYEMLIGYPPFCSETPQETYRKVMNWKETLVFPPEVPISEKAKDLILRFC-I 363 Query: 410 DPANRMGSYEGSNEIKQHPFFRGINWALVR 321 D NR+G+ G EIK HPFF G++W +R Sbjct: 364 DSENRIGN-SGVEEIKGHPFFEGVDWEHIR 392
>PKN1_RAT (Q63433) Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protein| kinase C-like 1) (Protein-kinase C-related kinase 1) (Protein kinase C-like PKN) (Serine-threonine protein kinase N) (Protease-activated kinase 1) (PAK-1) Length = 946 Score = 79.0 bits (193), Expect = 1e-14 Identities = 39/95 (41%), Positives = 60/95 (63%), Gaps = 2/95 (2%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW LG+ LYEML G +PF G + F +I++ ++R+P +S A ++ RLL R+P Sbjct: 801 DWWGLGVFLYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSAE--AIGIMRRLLRRNP 858 Query: 404 ANRMGSYE-GSNEIKQHPFFRGINW-ALVRGTAPP 306 R+GS E + ++K+ PFFR ++W AL+ PP Sbjct: 859 ERRLGSTERDAEDVKKQPFFRTLDWDALLARRLPP 893
>CBK1_YARLI (Q6CFS5) Serine/threonine-protein kinase CBK1 (EC 2.7.11.1)| Length = 588 Score = 79.0 bits (193), Expect = 1e-14 Identities = 41/102 (40%), Positives = 64/102 (62%), Gaps = 5/102 (4%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILH--KDIRFPASISVSLPARQLIYRLLHR 411 DWW+LG +++E L G+ PF + + T+ I++ + ++FP + +S + LI RLL Sbjct: 438 DWWSLGAIMFECLVGWPPFCSEQPRETYHKIINWRETLQFPDDVHLSPESEDLIRRLL-T 496 Query: 410 DPANRMGSYEGSNEIKQHPFFRGINWALVRG-TAP--PKLDA 294 NR+G G+NEIK HPFFRG++W+ +R AP PKL + Sbjct: 497 SSENRLGRIGGANEIKSHPFFRGVDWSSIREFNAPFVPKLSS 538
>ST38L_MOUSE (Q7TSE6) Serine/threonine-protein kinase 38-like (EC 2.7.11.1)| (NDR2 protein kinase) (Nuclear Dbf2-related kinase 2) Length = 464 Score = 78.6 bits (192), Expect = 1e-14 Identities = 38/90 (42%), Positives = 56/90 (62%), Gaps = 2/90 (2%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANIL--HKDIRFPASISVSLPARQLIYRLLHR 411 DWW+LG+++YEML G+ PF +T Q T+ ++ + + FP + VS A+ LI R Sbjct: 305 DWWSLGVIMYEMLIGFPPFCSETPQETYRKVMSWKETLAFPPEVPVSEKAKDLILRFC-T 363 Query: 410 DPANRMGSYEGSNEIKQHPFFRGINWALVR 321 D NR+G+ G EIK HPFF G++W +R Sbjct: 364 DSENRIGN-GGVEEIKGHPFFEGVDWGHIR 392
>PKN2_RAT (O08874) Serine/threonine-protein kinase N2 (EC 2.7.11.13) (Protein| kinase C-like 2) (Protein-kinase C-related kinase 2) (Protease-activated kinase 2) (PAK-2) (Fragment) Length = 842 Score = 78.6 bits (192), Expect = 1e-14 Identities = 38/96 (39%), Positives = 61/96 (63%), Gaps = 3/96 (3%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW LG+L+YEML G +PF G + F +I++ ++R+P +S A ++ RLL R+P Sbjct: 703 DWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTE--AISIMRRLLRRNP 760 Query: 404 ANRMGSYE-GSNEIKQHPFFRGINWA--LVRGTAPP 306 R+G+ E + ++K+HPFFR +W+ L + PP Sbjct: 761 ERRLGAGEKDAEDVKKHPFFRLTDWSALLDKKVKPP 796
>KS6B1_RAT (P67999) Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1)| (Ribosomal protein S6 kinase I) (S6K) (p70-S6K) Length = 525 Score = 78.6 bits (192), Expect = 1e-14 Identities = 41/96 (42%), Positives = 59/96 (61%), Gaps = 3/96 (3%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW+LG L+Y+ML G PF G+ R++T IL + P ++ AR L+ +LL R+ Sbjct: 275 DWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQE--ARDLLKKLLKRNA 332 Query: 404 ANRMGSYEG-SNEIKQHPFFRGINW--ALVRGTAPP 306 A+R+G+ G + E++ HPFFR INW L R PP Sbjct: 333 ASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPP 368
>KS6B1_RABIT (P67998) Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1)| (Ribosomal protein S6 kinase I) (S6K) (p70-S6K) Length = 525 Score = 78.6 bits (192), Expect = 1e-14 Identities = 41/96 (42%), Positives = 59/96 (61%), Gaps = 3/96 (3%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW+LG L+Y+ML G PF G+ R++T IL + P ++ AR L+ +LL R+ Sbjct: 275 DWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQE--ARDLLKKLLKRNA 332 Query: 404 ANRMGSYEG-SNEIKQHPFFRGINW--ALVRGTAPP 306 A+R+G+ G + E++ HPFFR INW L R PP Sbjct: 333 ASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPP 368
>KS6B1_MOUSE (Q8BSK8) Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1)| (Ribosomal protein S6 kinase I) (S6K) (p70-S6K) Length = 525 Score = 78.6 bits (192), Expect = 1e-14 Identities = 41/96 (42%), Positives = 59/96 (61%), Gaps = 3/96 (3%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW+LG L+Y+ML G PF G+ R++T IL + P ++ AR L+ +LL R+ Sbjct: 275 DWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQE--ARDLLKKLLKRNA 332 Query: 404 ANRMGSYEG-SNEIKQHPFFRGINW--ALVRGTAPP 306 A+R+G+ G + E++ HPFFR INW L R PP Sbjct: 333 ASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPP 368
>KS6B1_HUMAN (P23443) Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1)| (Ribosomal protein S6 kinase I) (S6K) (S6K1) (70 kDa ribosomal protein S6 kinase 1) (p70 S6 kinase alpha) (p70(S6K)-alpha) (p70-S6K) (p70-alpha) Length = 525 Score = 78.6 bits (192), Expect = 1e-14 Identities = 41/96 (42%), Positives = 59/96 (61%), Gaps = 3/96 (3%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW+LG L+Y+ML G PF G+ R++T IL + P ++ AR L+ +LL R+ Sbjct: 275 DWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQE--ARDLLKKLLKRNA 332 Query: 404 ANRMGSYEG-SNEIKQHPFFRGINW--ALVRGTAPP 306 A+R+G+ G + E++ HPFFR INW L R PP Sbjct: 333 ASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPP 368
>KS6AA_CHICK (P18652) Ribosomal protein S6 kinase 2 alpha (EC 2.7.11.1)| (Ribosomal protein S6 kinase II alpha) (S6KII-alpha) (P90-RSK) (MAP kinase-activated protein kinase 1) (MAPK-activated protein kinase 1) (MAPKAP kinase 1) (MAPKAPK-1) Length = 752 Score = 78.6 bits (192), Expect = 1e-14 Identities = 38/85 (44%), Positives = 55/85 (64%), Gaps = 1/85 (1%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW+ G+L++EML G PF+GK R+ T IL + P +S A+ L+ L R+P Sbjct: 262 DWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSAE--AQSLLRALFKRNP 319 Query: 404 ANRMGS-YEGSNEIKQHPFFRGINW 333 ANR+GS +G+ EIK+HPF+ I+W Sbjct: 320 ANRLGSGPDGAEEIKRHPFYSTIDW 344 Score = 38.9 bits (89), Expect = 0.011 Identities = 28/84 (33%), Positives = 43/84 (51%), Gaps = 6/84 (7%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASI------SVSLPARQLIYR 423 D W+LG+LLY ML G TPF T IL + S+ ++S A+ L+ + Sbjct: 613 DIWSLGVLLYTMLAGCTPFANGPSD-TPEEILTRIGGGKFSVNGGNWDTISDVAKDLVSK 671 Query: 422 LLHRDPANRMGSYEGSNEIKQHPF 351 +LH DP R+ + ++ QHP+ Sbjct: 672 MLHVDPHQRL----TAKQVLQHPW 691
>MAST2_MOUSE (Q60592) Microtubule-associated serine/threonine-protein kinase 2| (EC 2.7.11.1) Length = 1734 Score = 78.2 bits (191), Expect = 2e-14 Identities = 36/85 (42%), Positives = 53/85 (62%), Gaps = 1/85 (1%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLP-ARQLIYRLLHRD 408 DWWA+GI+LYE L G PF G T + F ++ +I +P P A+ L +LLH++ Sbjct: 648 DWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEIVWPEGDDALPPDAQDLTSKLLHQN 707 Query: 407 PANRMGSYEGSNEIKQHPFFRGINW 333 P R+G+ + E+KQHPFF G++W Sbjct: 708 PLERLGT-SSAYEVKQHPFFMGLDW 731
>PKN2_MOUSE (Q8BWW9) Serine/threonine-protein kinase N2 (EC 2.7.11.13) (Protein| kinase C-like 2) (Protein-kinase C-related kinase 2) Length = 983 Score = 78.2 bits (191), Expect = 2e-14 Identities = 35/86 (40%), Positives = 57/86 (66%), Gaps = 1/86 (1%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW LG+L+YEML G +PF G + F +I++ ++R+P +S A ++ RLL R+P Sbjct: 838 DWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTE--AISIMRRLLRRNP 895 Query: 404 ANRMGSYE-GSNEIKQHPFFRGINWA 330 R+G+ E + ++K+HPFFR +W+ Sbjct: 896 ERRLGAGEKDAEDVKKHPFFRLTDWS 921
>KS6A2_MOUSE (Q9WUT3) Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1)| (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (Protein-tyrosine kinase Mpk-9) (MAP kinase-activated protein kinase 1c) (M Length = 733 Score = 77.8 bits (190), Expect = 2e-14 Identities = 38/85 (44%), Positives = 54/85 (63%), Gaps = 1/85 (1%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW+ G+L++EML G PF+GK R+ T A IL + P +S A+ L+ L R+P Sbjct: 241 DWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLGMPQFLSAE--AQSLLRALFKRNP 298 Query: 404 ANRMGS-YEGSNEIKQHPFFRGINW 333 NR+G+ +G EIK+HPFF I+W Sbjct: 299 CNRLGAGVDGVEEIKRHPFFVTIDW 323 Score = 41.2 bits (95), Expect = 0.002 Identities = 27/83 (32%), Positives = 42/83 (50%), Gaps = 5/83 (6%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRG---KTRQRTFANILHKDIRFPAS--ISVSLPARQLIYRL 420 D W+LGILLY ML G+TPF T + A I S+S A+ ++ ++ Sbjct: 593 DVWSLGILLYTMLAGFTPFANGPDDTPEEILARIGSGKYALSGGNWDSISDAAKDVVSKM 652 Query: 419 LHRDPANRMGSYEGSNEIKQHPF 351 LH DP R+ + ++ +HP+ Sbjct: 653 LHVDPQQRLTAV----QVLKHPW 671
>PKN3_MOUSE (Q8K045) Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein| kinase PKN-beta) (Protein-kinase C-related kinase 3) Length = 878 Score = 77.8 bits (190), Expect = 2e-14 Identities = 43/96 (44%), Positives = 54/96 (56%), Gaps = 3/96 (3%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW LG+LLYEML G PF G T + F I+ D+ P +SV +LI +LL + P Sbjct: 730 DWWGLGVLLYEMLVGECPFPGDTEEEVFECIVSADVPCPHFLSVQ--GLELIQKLLQKSP 787 Query: 404 ANRMGSYE-GSNEIKQHPFFRGINW--ALVRGTAPP 306 R+G+ E + EIK PFFR NW L R PP Sbjct: 788 EKRLGAGERDAEEIKVQPFFRTTNWQALLARTVQPP 823
>YPK1_YEAST (P12688) Serine/threonine-protein kinase YPK1 (EC 2.7.11.1)| Length = 680 Score = 77.8 bits (190), Expect = 2e-14 Identities = 42/105 (40%), Positives = 59/105 (56%), Gaps = 2/105 (1%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW LG+LLYEML G P+ + + + IL + + FP A+ L+ LL RDP Sbjct: 527 DWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQEPLVFPDGF--DRDAKDLLIGLLSRDP 584 Query: 404 ANRMGSYEGSNEIKQHPFFRGINW--ALVRGTAPPKLDAPLFSKD 276 R+G Y G++EI+ HPFF ++W L++G PP A S D Sbjct: 585 TRRLG-YNGADEIRNHPFFSQLSWKRLLMKGYIPPYKPAVSNSMD 628
>SGK3_MOUSE (Q9ERE3) Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 3) (Serum/glucocorticoid-regulated kinase-like) (Cytokine independent survival kinase) Length = 496 Score = 77.4 bits (189), Expect = 3e-14 Identities = 41/104 (39%), Positives = 57/104 (54%), Gaps = 1/104 (0%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW LG +LYEMLYG PF + + NILHK + VSL A ++ LL ++ Sbjct: 343 DWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKPLNLRP--GVSLTAWSILEELLEKNR 400 Query: 404 ANRMGSYEGSNEIKQHPFFRGINWA-LVRGTAPPKLDAPLFSKD 276 NR+G+ E EI+ HPFF ++W LV+ PP + + D Sbjct: 401 QNRLGAKEDFLEIQNHPFFESLSWTDLVQKKIPPPFNPNVAGPD 444
>MAST2_HUMAN (Q6P0Q8) Microtubule-associated serine/threonine-protein kinase 2| (EC 2.7.11.1) Length = 1798 Score = 77.4 bits (189), Expect = 3e-14 Identities = 36/85 (42%), Positives = 53/85 (62%), Gaps = 1/85 (1%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLP-ARQLIYRLLHRD 408 DWWA+GI+LYE L G PF G T + F ++ +I +P P A+ L +LLH++ Sbjct: 707 DWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEIVWPEGDEALPPDAQDLTSKLLHQN 766 Query: 407 PANRMGSYEGSNEIKQHPFFRGINW 333 P R+G+ + E+KQHPFF G++W Sbjct: 767 PLERLGT-GSAYEVKQHPFFTGLDW 790
>KS6A2_HUMAN (Q15349) Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1)| (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (MAP kinase-activated protein kinase 1c) (MAPKAPK1C) Length = 733 Score = 77.0 bits (188), Expect = 4e-14 Identities = 44/107 (41%), Positives = 61/107 (57%), Gaps = 1/107 (0%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW+ G+L++EML G PF+GK R+ T A IL + P +S A+ L+ L R+P Sbjct: 241 DWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLGMPQFLSGE--AQSLLRALFKRNP 298 Query: 404 ANRMGS-YEGSNEIKQHPFFRGINWALVRGTAPPKLDAPLFSKDVGK 267 NR+G+ +G EIK+HPFF I+W T K P F VG+ Sbjct: 299 CNRLGAGIDGVEEIKRHPFFVTIDW----NTLYRKEIKPPFKPAVGR 341 Score = 40.8 bits (94), Expect = 0.003 Identities = 27/83 (32%), Positives = 42/83 (50%), Gaps = 5/83 (6%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRG---KTRQRTFANILHKDIRFPAS--ISVSLPARQLIYRL 420 D W+LGILLY ML G+TPF T + A I S+S A+ ++ ++ Sbjct: 593 DIWSLGILLYTMLAGFTPFANGPDDTPEEILARIGSGKYALSGGNWDSISDAAKDVVSKM 652 Query: 419 LHRDPANRMGSYEGSNEIKQHPF 351 LH DP R+ + ++ +HP+ Sbjct: 653 LHVDPHQRLTAM----QVLKHPW 671
>KS6A6_HUMAN (Q9UK32) Ribosomal protein S6 kinase alpha-6 (EC 2.7.11.1)| (S6K-alpha 6) (90 kDa ribosomal protein S6 kinase 6) (p90-RSK 6) (Ribosomal S6 kinase 4) (RSK-4) (pp90RSK4) Length = 745 Score = 77.0 bits (188), Expect = 4e-14 Identities = 39/84 (46%), Positives = 52/84 (61%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW+ G+L++EML G PF+GK R T IL + P +S A+ L+ L R+P Sbjct: 255 DWWSYGVLMFEMLTGTLPFQGKDRNETMNMILKAKLGMPQFLSAE--AQSLLRMLFKRNP 312 Query: 404 ANRMGSYEGSNEIKQHPFFRGINW 333 ANR+GS EG EIK+H FF I+W Sbjct: 313 ANRLGS-EGVEEIKRHLFFANIDW 335 Score = 38.1 bits (87), Expect = 0.019 Identities = 26/69 (37%), Positives = 34/69 (49%), Gaps = 6/69 (8%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASIS------VSLPARQLIYR 423 D W+LG+L Y ML GYTPF T IL + S+S +S A+ L+ Sbjct: 604 DIWSLGVLFYTMLAGYTPFANGPND-TPEEILLRIGNGKFSLSGGNWDNISDGAKDLLSH 662 Query: 422 LLHRDPANR 396 +LH DP R Sbjct: 663 MLHMDPHQR 671
>KPCE_HUMAN (Q02156) Protein kinase C epsilon type (EC 2.7.11.13)| (nPKC-epsilon) Length = 737 Score = 77.0 bits (188), Expect = 4e-14 Identities = 36/90 (40%), Positives = 54/90 (60%), Gaps = 3/90 (3%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWWALG+L+YEM+ G PF F +ILH D+ +P + +S A ++ + ++P Sbjct: 589 DWWALGVLMYEMMAGQPPFEADNEDDLFESILHDDVLYP--VWLSKEAVSILKAFMTKNP 646 Query: 404 ANRMG---SYEGSNEIKQHPFFRGINWALV 324 R+G S G + IKQHPFF+ I+W L+ Sbjct: 647 HKRLGCVASQNGEDAIKQHPFFKEIDWVLL 676
>SCK1_SCHPO (P50530) Serine/threonine-protein kinase sck1 (EC 2.7.11.1)| Length = 696 Score = 76.6 bits (187), Expect = 5e-14 Identities = 34/87 (39%), Positives = 56/87 (64%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 D+W+LG+L++EM G++PF Q+ + NI +RFP + +S R + LL+R+P Sbjct: 486 DFWSLGVLVFEMCCGWSPFYAPDVQQMYRNIAFGKVRFPKGV-LSSEGRSFVRGLLNRNP 544 Query: 404 ANRMGSYEGSNEIKQHPFFRGINWALV 324 +R+G+ + E+K+HPFF INW L+ Sbjct: 545 NHRLGAVADTTELKEHPFFADINWDLL 571
>PKN3_HUMAN (Q6P5Z2) Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein| kinase PKN-beta) (Protein-kinase C-related kinase 3) Length = 889 Score = 76.3 bits (186), Expect = 6e-14 Identities = 42/96 (43%), Positives = 54/96 (56%), Gaps = 3/96 (3%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW LG+LLYEML G PF G T + F I++ D +P +SV + I +LL + P Sbjct: 741 DWWGLGVLLYEMLVGECPFPGDTEEEVFDCIVNMDAPYPGFLSVQ--GLEFIQKLLQKCP 798 Query: 404 ANRMGSYE-GSNEIKQHPFFRGINW--ALVRGTAPP 306 R+G+ E + EIK PFFR NW L R PP Sbjct: 799 EKRLGAGEQDAEEIKVQPFFRTTNWQALLARTIQPP 834
>KS6AA_XENLA (P10665) Ribosomal protein S6 kinase 2 alpha (EC 2.7.11.1)| (Ribosomal protein S6 kinase II alpha) (S6KII-alpha) (P90-RSK) (MAP kinase-activated protein kinase 1) (MAPK-activated protein kinase 1) (MAPKAP kinase 1) (MAPKAPK-1) Length = 733 Score = 76.3 bits (186), Expect = 6e-14 Identities = 41/96 (42%), Positives = 58/96 (60%), Gaps = 3/96 (3%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW+ G+L++EML G PF+GK R+ T IL + P +S A+ L+ L R+P Sbjct: 244 DWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSNE--AQSLLRALFKRNP 301 Query: 404 ANRMGS-YEGSNEIKQHPFFRGINWALV--RGTAPP 306 NR+GS EG+ EIK+ PFF I+W + R +PP Sbjct: 302 TNRLGSAMEGAEEIKRQPFFSTIDWNKLFRREMSPP 337 Score = 46.2 bits (108), Expect = 7e-05 Identities = 30/69 (43%), Positives = 38/69 (55%), Gaps = 5/69 (7%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFR---GKTRQRTFANILHK--DIRFPASISVSLPARQLIYRL 420 D W+LGILLY ML GYTPF G T + A I +R +VS A+ L+ R+ Sbjct: 594 DIWSLGILLYTMLAGYTPFANGLGDTPEEILARIGSGKFTLRGGNWNTVSAAAKDLVSRM 653 Query: 419 LHRDPANRM 393 LH DP R+ Sbjct: 654 LHVDPHKRL 662
>SGK2_HUMAN (Q9HBY8) Serine/threonine-protein kinase Sgk2 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 2) Length = 427 Score = 76.3 bits (186), Expect = 6e-14 Identities = 37/84 (44%), Positives = 50/84 (59%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW LG +LYEML+G PF + + + NILH+ ++ P +V+ A L+ LLH+D Sbjct: 276 DWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLQIPGGRTVA--ACDLLQSLLHKDQ 333 Query: 404 ANRMGSYEGSNEIKQHPFFRGINW 333 R+GS EIK H FF INW Sbjct: 334 RQRLGSKADFLEIKNHVFFSPINW 357
>YPK2_YEAST (P18961) Serine/threonine-protein kinase YPK2/YKR2 (EC 2.7.11.1)| Length = 677 Score = 76.3 bits (186), Expect = 6e-14 Identities = 39/95 (41%), Positives = 57/95 (60%), Gaps = 2/95 (2%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW LGILLYEM+ G P+ + + IL + + FP + A+ L+ LL RDP Sbjct: 524 DWWTLGILLYEMMTGLPPYYDENVPVMYKKILQQPLLFPDGFDPA--AKDLLIGLLSRDP 581 Query: 404 ANRMGSYEGSNEIKQHPFFRGINW--ALVRGTAPP 306 + R+G G++EI+ HPFF+ I+W L++G PP Sbjct: 582 SRRLG-VNGTDEIRNHPFFKDISWKKLLLKGYIPP 615
>KPCE_RABIT (P10830) Protein kinase C epsilon type (EC 2.7.11.13)| (nPKC-epsilon) Length = 736 Score = 75.9 bits (185), Expect = 8e-14 Identities = 35/90 (38%), Positives = 54/90 (60%), Gaps = 3/90 (3%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWWALG+L+YEM+ G PF F +ILH D+ +P + +S A ++ + ++P Sbjct: 588 DWWALGVLMYEMMAGQPPFEADNEDDLFESILHDDVLYP--VWLSKEAVSILKAFMTKNP 645 Query: 404 ANRMG---SYEGSNEIKQHPFFRGINWALV 324 R+G + G + IKQHPFF+ I+W L+ Sbjct: 646 HKRLGCVAAQNGEDAIKQHPFFKEIDWVLL 675
>CBK1_PNECA (Q6TGC6) Serine/threonine-protein kinase CBK1 (EC 2.7.11.1)| Length = 507 Score = 75.9 bits (185), Expect = 8e-14 Identities = 37/95 (38%), Positives = 57/95 (60%), Gaps = 2/95 (2%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILH--KDIRFPASISVSLPARQLIYRLLHR 411 DWW+LG +++E L G+ PF + T+ I++ +++ FP + +S A LI +LL Sbjct: 353 DWWSLGAIMFECLIGWPPFCSENAHETYRKIINWRENLYFPEDLHLSAEAEDLIRKLL-T 411 Query: 410 DPANRMGSYEGSNEIKQHPFFRGINWALVRGTAPP 306 R+G Y G+N+IK HPFFRG+NW +R P Sbjct: 412 SADQRLGRY-GANDIKLHPFFRGVNWDTIREINAP 445
>KPCE_RAT (P09216) Protein kinase C epsilon type (EC 2.7.11.13)| (nPKC-epsilon) Length = 737 Score = 75.9 bits (185), Expect = 8e-14 Identities = 35/90 (38%), Positives = 54/90 (60%), Gaps = 3/90 (3%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWWALG+L+YEM+ G PF F +ILH D+ +P + +S A ++ + ++P Sbjct: 589 DWWALGVLMYEMMAGQPPFEADNEDDLFESILHDDVLYP--VWLSKEAVSILKAFMTKNP 646 Query: 404 ANRMG---SYEGSNEIKQHPFFRGINWALV 324 R+G + G + IKQHPFF+ I+W L+ Sbjct: 647 HKRLGCVAAQNGEDAIKQHPFFKEIDWVLL 676
>KPCE_MOUSE (P16054) Protein kinase C epsilon type (EC 2.7.11.13)| (nPKC-epsilon) Length = 737 Score = 75.9 bits (185), Expect = 8e-14 Identities = 35/90 (38%), Positives = 54/90 (60%), Gaps = 3/90 (3%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWWALG+L+YEM+ G PF F +ILH D+ +P + +S A ++ + ++P Sbjct: 589 DWWALGVLMYEMMAGQPPFEADNEDDLFESILHDDVLYP--VWLSKEAVSILKAFMTKNP 646 Query: 404 ANRMG---SYEGSNEIKQHPFFRGINWALV 324 R+G + G + IKQHPFF+ I+W L+ Sbjct: 647 HKRLGCVAAQNGEDAIKQHPFFKEIDWVLL 676
>KS6AB_XENLA (P10666) Ribosomal protein S6 kinase 2 beta (EC 2.7.11.1)| (Ribosomal protein S6 kinase II beta) (S6KII-beta) (P90-RSK) Length = 629 Score = 75.5 bits (184), Expect = 1e-13 Identities = 40/96 (41%), Positives = 58/96 (60%), Gaps = 3/96 (3%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW+ G+L++EML G PF+GK R+ T IL + P +S A+ L+ L R+ Sbjct: 244 DWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSNE--AQSLLRALFKRNA 301 Query: 404 ANRMGS-YEGSNEIKQHPFFRGINWALV--RGTAPP 306 NR+GS EG+ E+K+HPFF I+W + R +PP Sbjct: 302 TNRLGSGVEGAEELKRHPFFSTIDWNKLYRRELSPP 337 Score = 36.6 bits (83), Expect = 0.055 Identities = 19/34 (55%), Positives = 21/34 (61%), Gaps = 3/34 (8%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFR---GKTRQRTFANI 492 D W+LGILLY ML GYTPF G T + A I Sbjct: 594 DIWSLGILLYTMLAGYTPFANGPGDTPEEILARI 627
>ORB6_SCHPO (O13310) Serine/threonine-protein kinase orb6 (EC 2.7.11.1)| Length = 469 Score = 75.5 bits (184), Expect = 1e-13 Identities = 39/95 (41%), Positives = 59/95 (62%), Gaps = 2/95 (2%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILH--KDIRFPASISVSLPARQLIYRLLHR 411 DWW+LG +++E L G+ PF + T+ I++ + + FP I +S+ AR L+ RL+ Sbjct: 314 DWWSLGAIMFECLIGWPPFCSENSHETYRKIINWRETLTFPNDIHLSIEARDLMDRLM-T 372 Query: 410 DPANRMGSYEGSNEIKQHPFFRGINWALVRGTAPP 306 D +R+G G+ EI QHPFF GI+W +R TA P Sbjct: 373 DSEHRLGR-GGAIEIMQHPFFTGIDWDHIRETAAP 406
>SGK2_MOUSE (Q9QZS5) Serine/threonine-protein kinase Sgk2 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 2) Length = 367 Score = 75.5 bits (184), Expect = 1e-13 Identities = 37/84 (44%), Positives = 50/84 (59%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW LG +LYEML+G PF + + NILH+ ++ P +V+ A L+ LLH+D Sbjct: 216 DWWCLGAVLYEMLHGLPPFFNTDVAQMYENILHQPLQIPGGRTVA--ACDLLQGLLHKDQ 273 Query: 404 ANRMGSYEGSNEIKQHPFFRGINW 333 R+GS E +IK H FF INW Sbjct: 274 RQRLGSKEDFLDIKNHMFFSPINW 297
>KAPB_SCHPO (P40376) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) Length = 512 Score = 75.5 bits (184), Expect = 1e-13 Identities = 43/121 (35%), Positives = 68/121 (56%), Gaps = 1/121 (0%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW+LGIL++EML GY PF + + + NIL + +P+ S + + L+ LL RD Sbjct: 379 DWWSLGILIFEMLAGYPPFYSENPMKLYENILEGKVNYPSYFSPA--SIDLLSHLLQRDI 436 Query: 404 ANRMGSY-EGSNEIKQHPFFRGINWALVRGTAPPKLDAPLFSKDVGKGMGDAAAADNGTD 228 R G+ +GS +I HP+FR I+W + K++ P + + GMGD++ D D Sbjct: 437 TCRYGNLKDGSMDIIMHPWFRDISWDKI---LTRKIEVP-YVPPIQAGMGDSSQFDAYAD 492 Query: 227 M 225 + Sbjct: 493 V 493
>SGK2_RAT (Q8R4U9) Serine/threonine-protein kinase Sgk2 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 2) (Fragment) Length = 302 Score = 75.5 bits (184), Expect = 1e-13 Identities = 37/84 (44%), Positives = 50/84 (59%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW LG +LYEML+G PF + + NILH+ ++ P +V+ A L+ LLH+D Sbjct: 199 DWWCLGAVLYEMLHGLPPFFNTDVAQMYENILHQPLQIPGGRTVA--ACDLLQGLLHKDQ 256 Query: 404 ANRMGSYEGSNEIKQHPFFRGINW 333 R+GS E +IK H FF INW Sbjct: 257 RQRLGSKEDFLDIKNHMFFSPINW 280
>KPC3_DROME (P13678) Protein kinase C (EC 2.7.11.13) (PKC) (dPKC98F)| Length = 634 Score = 75.1 bits (183), Expect = 1e-13 Identities = 35/95 (36%), Positives = 54/95 (56%), Gaps = 2/95 (2%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWWALG+L+YEM+ G PF F +I+H D+ +P + +S A ++ L ++P Sbjct: 484 DWWALGVLMYEMMAGQPPFEADNEDELFDSIMHDDVLYP--VWLSREAVSILKGFLTKNP 541 Query: 404 ANRMGSYEGSNEIKQHPFFRGINWALV--RGTAPP 306 R+G NEI++HPFF ++W + R PP Sbjct: 542 EQRLGCTGDENEIRKHPFFAKLDWKELEKRNIKPP 576
>KS6A1_HUMAN (Q15418) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 735 Score = 75.1 bits (183), Expect = 1e-13 Identities = 37/85 (43%), Positives = 54/85 (63%), Gaps = 1/85 (1%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW+ G+L++EML G PF+GK R+ T IL + P +S A+ L+ L R+P Sbjct: 244 DWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSTE--AQSLLRALFKRNP 301 Query: 404 ANRMGS-YEGSNEIKQHPFFRGINW 333 ANR+GS +G+ EIK+H F+ I+W Sbjct: 302 ANRLGSGPDGAEEIKRHVFYSTIDW 326 Score = 43.9 bits (102), Expect = 3e-04 Identities = 32/84 (38%), Positives = 45/84 (53%), Gaps = 6/84 (7%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHK--DIRFPAS----ISVSLPARQLIYR 423 D W+LGILLY ML GYTPF T IL + +F S +VS A+ L+ + Sbjct: 596 DIWSLGILLYTMLAGYTPFANGPSD-TPEEILTRIGSGKFTLSGGNWNTVSETAKDLVSK 654 Query: 422 LLHRDPANRMGSYEGSNEIKQHPF 351 +LH DP R+ + ++ QHP+ Sbjct: 655 MLHVDPHQRL----TAKQVLQHPW 674
>AKT3_MOUSE (Q9WUA6) RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma) Length = 479 Score = 74.7 bits (182), Expect = 2e-13 Identities = 35/85 (41%), Positives = 54/85 (63%), Gaps = 1/85 (1%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW LG+++YEM+ G PF + ++ F IL +DI+FP ++S A+ L+ LL +DP Sbjct: 328 DWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSD--AKSLLSGLLIKDP 385 Query: 404 ANRM-GSYEGSNEIKQHPFFRGINW 333 R+ G + + EI +H FF G+NW Sbjct: 386 NKRLGGGPDDAKEIMRHSFFSGVNW 410
>AKT3_HUMAN (Q9Y243) RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma) (STK-2) Length = 479 Score = 74.7 bits (182), Expect = 2e-13 Identities = 35/85 (41%), Positives = 54/85 (63%), Gaps = 1/85 (1%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW LG+++YEM+ G PF + ++ F IL +DI+FP ++S A+ L+ LL +DP Sbjct: 328 DWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSD--AKSLLSGLLIKDP 385 Query: 404 ANRM-GSYEGSNEIKQHPFFRGINW 333 R+ G + + EI +H FF G+NW Sbjct: 386 NKRLGGGPDDAKEIMRHSFFSGVNW 410
>KPCA_MOUSE (P20444) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 74.7 bits (182), Expect = 2e-13 Identities = 39/108 (36%), Positives = 59/108 (54%), Gaps = 1/108 (0%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWWA G+LLYEML G PF G+ F +I+ ++ +P S+S A + L+ + P Sbjct: 519 DWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLSKE--AVSICKGLMTKQP 576 Query: 404 ANRMG-SYEGSNEIKQHPFFRGINWALVRGTAPPKLDAPLFSKDVGKG 264 A R+G EG ++++H FFR I+W + ++ P K GKG Sbjct: 577 AKRLGCGPEGERDVREHAFFRRIDWEKLENR---EIQPPFKPKVCGKG 621
>SCH9_YEAST (P11792) Serine/threonine-protein kinase SCH9 (EC 2.7.11.1)| Length = 823 Score = 74.7 bits (182), Expect = 2e-13 Identities = 35/103 (33%), Positives = 61/103 (59%), Gaps = 1/103 (0%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 D+W+LG+L++EM G++PF + Q+ + I ++FP + +S R + LL+R+P Sbjct: 593 DFWSLGVLIFEMCCGWSPFFAENNQKMYQKIAFGKVKFPRDV-LSQEGRSFVKGLLNRNP 651 Query: 404 ANRMGSYEGSNEIKQHPFFRGINW-ALVRGTAPPKLDAPLFSK 279 +R+G+ + E++ HPFF I+W AL + PP L S+ Sbjct: 652 KHRLGAIDDGRELRAHPFFADIDWEALKQKKIPPPFKPHLVSE 694
>KS6A1_RAT (Q63531) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 735 Score = 74.7 bits (182), Expect = 2e-13 Identities = 37/85 (43%), Positives = 54/85 (63%), Gaps = 1/85 (1%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW+ G+L++EML G PF+GK R+ T IL + P +S A+ L+ L R+P Sbjct: 244 DWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSTE--AQSLLRALFKRNP 301 Query: 404 ANRMGS-YEGSNEIKQHPFFRGINW 333 ANR+GS +G+ EIK+H F+ I+W Sbjct: 302 ANRLGSGPDGAEEIKRHIFYSTIDW 326 Score = 44.3 bits (103), Expect = 3e-04 Identities = 28/83 (33%), Positives = 41/83 (49%), Gaps = 5/83 (6%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFR---GKTRQRTFANILHKDIRFPAS--ISVSLPARQLIYRL 420 D W+LG+LLY ML GYTPF T + I +VS A+ L+ ++ Sbjct: 596 DIWSLGVLLYTMLAGYTPFANGPSDTPEEILTRISSGKFTLSGGNWNTVSETAKDLVSKM 655 Query: 419 LHRDPANRMGSYEGSNEIKQHPF 351 LH DP R+ + ++ QHP+ Sbjct: 656 LHVDPHQRL----TAKQVLQHPW 674
>KPCA_RAT (P05696) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 74.3 bits (181), Expect = 2e-13 Identities = 39/108 (36%), Positives = 59/108 (54%), Gaps = 1/108 (0%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWWA G+LLYEML G PF G+ F +I+ ++ +P S+S A + L+ + P Sbjct: 519 DWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLSKE--AVSICKGLMTKHP 576 Query: 404 ANRMG-SYEGSNEIKQHPFFRGINWALVRGTAPPKLDAPLFSKDVGKG 264 A R+G EG ++++H FFR I+W + ++ P K GKG Sbjct: 577 AKRLGCGPEGERDVREHAFFRRIDWEKLENR---EIQPPFKPKVCGKG 621
>KPCA_RABIT (P10102) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 74.3 bits (181), Expect = 2e-13 Identities = 39/108 (36%), Positives = 59/108 (54%), Gaps = 1/108 (0%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWWA G+LLYEML G PF G+ F +I+ ++ +P S+S A + L+ + P Sbjct: 519 DWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLSKE--AVSICKGLMTKHP 576 Query: 404 ANRMG-SYEGSNEIKQHPFFRGINWALVRGTAPPKLDAPLFSKDVGKG 264 A R+G EG ++++H FFR I+W + ++ P K GKG Sbjct: 577 AKRLGCGPEGERDVREHAFFRRIDWEKLENR---EIQPPFKPKVCGKG 621
>KPCA_HUMAN (P17252) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 74.3 bits (181), Expect = 2e-13 Identities = 39/108 (36%), Positives = 59/108 (54%), Gaps = 1/108 (0%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWWA G+LLYEML G PF G+ F +I+ ++ +P S+S A + L+ + P Sbjct: 519 DWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLSKE--AVSICKGLMTKHP 576 Query: 404 ANRMG-SYEGSNEIKQHPFFRGINWALVRGTAPPKLDAPLFSKDVGKG 264 A R+G EG ++++H FFR I+W + ++ P K GKG Sbjct: 577 AKRLGCGPEGERDVREHAFFRRIDWEKLENR---EIQPPFKPKVCGKG 621
>MRCKA_HUMAN (Q5VT25) Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1)| (CDC42-binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha Length = 1732 Score = 74.3 bits (181), Expect = 2e-13 Identities = 41/96 (42%), Positives = 60/96 (62%), Gaps = 3/96 (3%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANIL-HKD-IRFPASIS-VSLPARQLIYRLLH 414 DWW+LG+ +YEMLYG TPF ++ T+ I+ HK+ +FPA ++ VS A+ LI RL+ Sbjct: 264 DWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPAQVTDVSENAKDLIRRLI- 322 Query: 413 RDPANRMGSYEGSNEIKQHPFFRGINWALVRGTAPP 306 +R+G G + K+HPFF GI+W +R P Sbjct: 323 CSREHRLGQ-NGIEDFKKHPFFSGIDWDNIRNCEAP 357
>KPC1_DROME (P05130) Protein kinase C, brain isozyme (EC 2.7.11.13) (PKC)| (dPKC53E(BR)) Length = 679 Score = 74.3 bits (181), Expect = 2e-13 Identities = 46/129 (35%), Positives = 63/129 (48%), Gaps = 3/129 (2%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWWA G+LLYEML G PF G+ + FA I ++ +P S+S A++ L + P Sbjct: 531 DWWAYGVLLYEMLVGQPPFDGEDEEELFAAITDHNVSYPKSLSKE--AKEACKGFLTKQP 588 Query: 404 ANRMG-SYEGSNEIKQHPFFRGINWALV--RGTAPPKLDAPLFSKDVGKGMGDAAAADNG 234 R+G G +++ HPFFR I+W + R PP KDV D Sbjct: 589 NKRLGCGSSGEEDVRLHPFFRRIDWEKIENREVQPPFKPKIKHRKDVSN--FDKQFTSEK 646 Query: 233 TDMF*TKKV 207 TD+ T KV Sbjct: 647 TDLTPTDKV 655
>SGK1_HUMAN (O00141) Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 1) Length = 431 Score = 74.3 bits (181), Expect = 2e-13 Identities = 37/84 (44%), Positives = 50/84 (59%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW LG +LYEMLYG PF + + NIL+K ++ +I+ S AR L+ LL +D Sbjct: 279 DWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNS--ARHLLEGLLQKDR 336 Query: 404 ANRMGSYEGSNEIKQHPFFRGINW 333 R+G+ + EIK H FF INW Sbjct: 337 TKRLGAKDDFMEIKSHVFFSLINW 360
>KS6A3_MOUSE (P18654) Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1)| (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (MAP kinase-activated protein kinase 1b) (MAPKAPK1B) Length = 740 Score = 74.3 bits (181), Expect = 2e-13 Identities = 37/85 (43%), Positives = 53/85 (62%), Gaps = 1/85 (1%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW+ G+L++EML G PF+GK R+ T IL + P +S A+ L+ L R+P Sbjct: 250 DWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPE--AQSLLRMLFKRNP 307 Query: 404 ANRMGS-YEGSNEIKQHPFFRGINW 333 ANR+G+ +G EIK+H FF I+W Sbjct: 308 ANRLGAGPDGVEEIKRHSFFSTIDW 332 Score = 43.9 bits (102), Expect = 3e-04 Identities = 33/103 (32%), Positives = 49/103 (47%), Gaps = 5/103 (4%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRG---KTRQRTFANILHKDIRFPASI--SVSLPARQLIYRL 420 D W+LG+LLY ML GYTPF T + A I SVS A+ L+ ++ Sbjct: 600 DIWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTAKDLVSKM 659 Query: 419 LHRDPANRMGSYEGSNEIKQHPFFRGINWALVRGTAPPKLDAP 291 LH DP R+ + + +HP+ ++W + + DAP Sbjct: 660 LHVDPHQRL----TAALVLRHPWI--VHWDQLPQYQLNRQDAP 696
>KS6A3_HUMAN (P51812) Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1)| (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protei Length = 740 Score = 74.3 bits (181), Expect = 2e-13 Identities = 37/85 (43%), Positives = 53/85 (62%), Gaps = 1/85 (1%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW+ G+L++EML G PF+GK R+ T IL + P +S A+ L+ L R+P Sbjct: 250 DWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPE--AQSLLRMLFKRNP 307 Query: 404 ANRMGS-YEGSNEIKQHPFFRGINW 333 ANR+G+ +G EIK+H FF I+W Sbjct: 308 ANRLGAGPDGVEEIKRHSFFSTIDW 332 Score = 43.9 bits (102), Expect = 3e-04 Identities = 33/103 (32%), Positives = 49/103 (47%), Gaps = 5/103 (4%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRG---KTRQRTFANILHKDIRFPASI--SVSLPARQLIYRL 420 D W+LG+LLY ML GYTPF T + A I SVS A+ L+ ++ Sbjct: 600 DIWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTAKDLVSKM 659 Query: 419 LHRDPANRMGSYEGSNEIKQHPFFRGINWALVRGTAPPKLDAP 291 LH DP R+ + + +HP+ ++W + + DAP Sbjct: 660 LHVDPHQRL----TAALVLRHPWI--VHWDQLPQYQLNRQDAP 696
>AKT1_HUMAN (P31749) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase B) (PKB) (C-AKT) Length = 480 Score = 73.9 bits (180), Expect = 3e-13 Identities = 39/96 (40%), Positives = 57/96 (59%), Gaps = 3/96 (3%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW LG+++YEM+ G PF + ++ F IL ++IRFP ++ A+ L+ LL +DP Sbjct: 331 DWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPE--AKSLLSGLLKKDP 388 Query: 404 ANRM-GSYEGSNEIKQHPFFRGINWALV--RGTAPP 306 R+ G E + EI QH FF GI W V + +PP Sbjct: 389 KQRLGGGSEDAKEIMQHRFFAGIVWQHVYEKKLSPP 424
>AKT3_RAT (Q63484) RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma) Length = 454 Score = 73.9 bits (180), Expect = 3e-13 Identities = 35/85 (41%), Positives = 53/85 (62%), Gaps = 1/85 (1%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW LG+++YEM+ G PF + ++ F IL +DI+FP ++S A+ L+ LL +DP Sbjct: 328 DWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSD--AKSLLSGLLIKDP 385 Query: 404 ANRM-GSYEGSNEIKQHPFFRGINW 333 R+ G + EI +H FF G+NW Sbjct: 386 NKRLGGGPDDPKEIMRHSFFSGVNW 410
>SGK1_MOUSE (Q9WVC6) Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 1) Length = 431 Score = 73.9 bits (180), Expect = 3e-13 Identities = 37/84 (44%), Positives = 50/84 (59%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW LG +LYEMLYG PF + + NIL+K ++ +I+ S AR L+ LL +D Sbjct: 279 DWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNS--ARHLLEGLLQKDR 336 Query: 404 ANRMGSYEGSNEIKQHPFFRGINW 333 R+G+ + EIK H FF INW Sbjct: 337 TKRLGAKDDFMEIKSHIFFSLINW 360
>GAD8_SCHPO (Q9P7J8) Serine/threonine-protein kinase gad8 (EC 2.7.11.1)| Length = 569 Score = 73.9 bits (180), Expect = 3e-13 Identities = 38/84 (45%), Positives = 49/84 (58%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW LG+LLYEM+ G PF + + IL +RFP +I A+ L+ LL R P Sbjct: 410 DWWTLGVLLYEMITGLPPFYDENINEMYRKILQDPLRFPDNIDEK--AKDLLSGLLTRAP 467 Query: 404 ANRMGSYEGSNEIKQHPFFRGINW 333 R+GS G+ EIK HPFF I+W Sbjct: 468 EKRLGS-GGAQEIKNHPFFDDIDW 490
>KRAC_DICDI (P54644) RAC-family serine/threonine-protein kinase homolog (EC| 2.7.11.1) Length = 444 Score = 73.6 bits (179), Expect = 4e-13 Identities = 41/94 (43%), Positives = 53/94 (56%), Gaps = 1/94 (1%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW+ G LLYEML G PF + Q + I+ + + FP IS AR L+ +LL RDP Sbjct: 301 DWWSFGSLLYEMLTGLPPFYNQDVQEMYRKIMMEKLSFPHFISPD--ARSLLEQLLERDP 358 Query: 404 ANRMGSYEGSNEIKQHPFFRGINW-ALVRGTAPP 306 R+ N IK+HPFFR I+W L + PP Sbjct: 359 EKRLAD---PNLIKRHPFFRSIDWEQLFQKNIPP 389
>AKT2_HUMAN (P31751) RAC-beta serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta) Length = 481 Score = 73.2 bits (178), Expect = 5e-13 Identities = 35/85 (41%), Positives = 52/85 (61%), Gaps = 1/85 (1%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW LG+++YEM+ G PF + +R F IL ++IRFP ++S A+ L+ LL +DP Sbjct: 332 DWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRTLSPE--AKSLLAGLLKKDP 389 Query: 404 ANRM-GSYEGSNEIKQHPFFRGINW 333 R+ G + E+ +H FF INW Sbjct: 390 KQRLGGGPSDAKEVMEHRFFLSINW 414
>KS6A4_MOUSE (Q9Z2B9) Ribosomal protein S6 kinase alpha-4 (EC 2.7.11.1) (Nuclear| mitogen-and stress-activated protein kinase 2) (90 kDa ribosomal protein S6 kinase 4) (RSK-like protein kinase) (RLSK) Length = 773 Score = 73.2 bits (178), Expect = 5e-13 Identities = 38/101 (37%), Positives = 63/101 (62%), Gaps = 3/101 (2%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRF--PASISVSLPARQLIYRLLHR 411 DWW+LGILL+E+L G +PF + + T A + + ++ P + + A+ L+ RLL + Sbjct: 220 DWWSLGILLFELLTGASPFTLEGERNTQAEVSRRILKCSPPFPLRIGPVAQDLLQRLLCK 279 Query: 410 DPANRMGS-YEGSNEIKQHPFFRGINWALVRGTAPPKLDAP 291 DP R+G+ +G+ E+K HPFF+G++W + A K+ AP Sbjct: 280 DPKKRLGAGPQGAQEVKSHPFFQGLDWWAL---AARKIPAP 317 Score = 39.3 bits (90), Expect = 0.008 Identities = 42/120 (35%), Positives = 58/120 (48%), Gaps = 9/120 (7%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKT---RQRTFANILHK--DIRF----PASISVSLPARQL 432 D W+LG++LY ML G PF+G + Q A I+ K + RF A VS A++L Sbjct: 591 DLWSLGVILYMMLSGQVPFQGASGQGGQSQAAEIMCKIREGRFSLDGEAWQGVSEEAKEL 650 Query: 431 IYRLLHRDPANRMGSYEGSNEIKQHPFFRGINWALVRGTAPPKLDAPLFSKDVGKGMGDA 252 + LL DPA R+ EG R +W L G+A + PL + DV + G A Sbjct: 651 VRGLLTVDPAKRL-KLEG---------LRSSSW-LQDGSA--RSSPPLRTPDVLESSGPA 697
>PCK1_SCHPO (P36582) Protein kinase C-like 1 (EC 2.7.11.13)| Length = 988 Score = 73.2 bits (178), Expect = 5e-13 Identities = 37/85 (43%), Positives = 52/85 (61%), Gaps = 1/85 (1%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWWA G+L+Y+ML G +PF+G+ + F IL + FP I++ A L+ LL RDP Sbjct: 846 DWWAFGVLMYQMLLGQSPFKGEDEEEIFDAILSDEPLFP--INMPADAVSLLRGLLTRDP 903 Query: 404 ANRMGS-YEGSNEIKQHPFFRGINW 333 R+GS + +NE+ HPFF I W Sbjct: 904 NQRLGSGPKDANEVMAHPFFASIVW 928
>SGK1_RABIT (Q9XT18) Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 1) Length = 431 Score = 73.2 bits (178), Expect = 5e-13 Identities = 36/84 (42%), Positives = 50/84 (59%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW LG +LYEMLYG PF + + NIL+K ++ +I+ S AR L+ LL +D Sbjct: 279 DWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNS--ARHLLEGLLQKDR 336 Query: 404 ANRMGSYEGSNEIKQHPFFRGINW 333 R+G+ + EI+ H FF INW Sbjct: 337 TKRLGAKDDFMEIRNHVFFSLINW 360
>AKT1_BOVIN (Q01314) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase B) (PKB) Length = 480 Score = 72.8 bits (177), Expect = 7e-13 Identities = 36/85 (42%), Positives = 52/85 (61%), Gaps = 1/85 (1%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW LG+++YEM+ G PF + ++ F IL ++IRFP ++S A+ L+ LL +DP Sbjct: 331 DWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLSPE--AKSLLSGLLKKDP 388 Query: 404 ANRM-GSYEGSNEIKQHPFFRGINW 333 R+ G E + EI QH FF I W Sbjct: 389 KQRLGGGSEDAKEIMQHRFFASIVW 413
>AKT2A_XENLA (Q7ZX15) RAC-beta serine/threonine-protein kinase-A (EC 2.7.11.1)| (RAC-PK-beta-A) (Protein kinase Akt-2-A) (Protein kinase B, beta-A) (PKB beta-A) Length = 486 Score = 72.8 bits (177), Expect = 7e-13 Identities = 39/96 (40%), Positives = 55/96 (57%), Gaps = 3/96 (3%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW LG+++YEM+ G PF + +R F IL ++IRFP ++S A+ L+ LL +DP Sbjct: 337 DWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRTLSPE--AKSLLAGLLKKDP 394 Query: 404 ANRM-GSYEGSNEIKQHPFFRGINWALV--RGTAPP 306 R+ G + E+ H FF INW V R PP Sbjct: 395 KQRLGGGPNDAQEVMSHRFFVSINWQDVTERKLTPP 430
>MRCKA_RAT (O54874) Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1)| (CDC42-binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) Length = 1732 Score = 72.8 bits (177), Expect = 7e-13 Identities = 40/96 (41%), Positives = 59/96 (61%), Gaps = 3/96 (3%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANIL-HKD-IRFPASIS-VSLPARQLIYRLLH 414 DWW+LG+ +YEMLYG TPF ++ T+ I+ HK+ +FP ++ VS A+ LI RL+ Sbjct: 264 DWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPTQVTDVSENAKDLIRRLI- 322 Query: 413 RDPANRMGSYEGSNEIKQHPFFRGINWALVRGTAPP 306 +R+G G + K+HPFF GI+W +R P Sbjct: 323 CSREHRLGQ-NGIEDFKKHPFFSGIDWDNIRNCEAP 357
>KPCB_MOUSE (P68404) Protein kinase C beta type (EC 2.7.11.13) (PKC-beta)| (PKC-B) Length = 672 Score = 72.8 bits (177), Expect = 7e-13 Identities = 35/85 (41%), Positives = 50/85 (58%), Gaps = 1/85 (1%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWWA G+LLYEML G PF G+ F +I+ ++ +P S+S A + L+ + P Sbjct: 522 DWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVA--ICKGLMTKHP 579 Query: 404 ANRMG-SYEGSNEIKQHPFFRGINW 333 R+G EG +IK+H FFR I+W Sbjct: 580 GKRLGCGPEGERDIKEHAFFRYIDW 604
>KPCB_BOVIN (P05126) Protein kinase C beta type (EC 2.7.11.13) (PKC-beta)| (PKC-B) Length = 672 Score = 72.8 bits (177), Expect = 7e-13 Identities = 35/85 (41%), Positives = 50/85 (58%), Gaps = 1/85 (1%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWWA G+LLYEML G PF G+ F +I+ ++ +P S+S A + L+ + P Sbjct: 522 DWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVA--ICKGLITKHP 579 Query: 404 ANRMG-SYEGSNEIKQHPFFRGINW 333 R+G EG +IK+H FFR I+W Sbjct: 580 GKRLGCGPEGERDIKEHAFFRYIDW 604
>AKT2B_XENLA (Q6IP76) RAC-beta serine/threonine-protein kinase-B (EC 2.7.11.1)| (RAC-PK-beta-B) (Protein kinase Akt-2-B) (Protein kinase B, beta-B) (PKB beta-B) Length = 485 Score = 72.8 bits (177), Expect = 7e-13 Identities = 38/96 (39%), Positives = 56/96 (58%), Gaps = 3/96 (3%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW LG+++YEM+ G PF + +R F IL ++ RFP ++S A+ L+ LL +DP Sbjct: 336 DWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEETRFPRTLSPE--AKSLLAGLLKKDP 393 Query: 404 ANRM-GSYEGSNEIKQHPFFRGINWALV--RGTAPP 306 R+ G + + E+ H FF INW V R +PP Sbjct: 394 KQRLGGGPDDAQEVMSHGFFASINWQDVTERKLSPP 429
>KPCB_RAT (P68403) Protein kinase C beta type (EC 2.7.11.13) (PKC-beta)| (PKC-B) Length = 670 Score = 72.8 bits (177), Expect = 7e-13 Identities = 35/85 (41%), Positives = 50/85 (58%), Gaps = 1/85 (1%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWWA G+LLYEML G PF G+ F +I+ ++ +P S+S A + L+ + P Sbjct: 522 DWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVA--ICKGLMTKHP 579 Query: 404 ANRMG-SYEGSNEIKQHPFFRGINW 333 R+G EG +IK+H FFR I+W Sbjct: 580 GKRLGCGPEGERDIKEHAFFRYIDW 604
>KPCB_HUMAN (P05771) Protein kinase C beta type (EC 2.7.11.13) (PKC-beta)| (PKC-B) Length = 670 Score = 72.8 bits (177), Expect = 7e-13 Identities = 35/85 (41%), Positives = 50/85 (58%), Gaps = 1/85 (1%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWWA G+LLYEML G PF G+ F +I+ ++ +P S+S A + L+ + P Sbjct: 522 DWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVA--ICKGLMTKHP 579 Query: 404 ANRMG-SYEGSNEIKQHPFFRGINW 333 R+G EG +IK+H FFR I+W Sbjct: 580 GKRLGCGPEGERDIKEHAFFRYIDW 604
>PCK2_SCHPO (P36583) Protein kinase C-like 2 (EC 2.7.11.13)| Length = 1016 Score = 72.8 bits (177), Expect = 7e-13 Identities = 40/108 (37%), Positives = 62/108 (57%), Gaps = 6/108 (5%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWWA G+L+Y+ML G +PFRG+ + F IL + +P I + + ++ +LL RDP Sbjct: 865 DWWAFGVLIYQMLLGQSPFRGEDEEEIFDAILSDEPLYP--IHMPRDSVSILQQLLTRDP 922 Query: 404 ANRMGS-YEGSNEIKQHPFFRGINWALV--RGTAP---PKLDAPLFSK 279 R+GS + ++ HPFF INW + + T P P L++P +K Sbjct: 923 KKRLGSGPNDAEDVMTHPFFSNINWDDIYHKRTQPPYIPSLNSPTDTK 970
>KPCA_BOVIN (P04409) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 72.8 bits (177), Expect = 7e-13 Identities = 38/108 (35%), Positives = 58/108 (53%), Gaps = 1/108 (0%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWWA G+LLYEML G PF G+ F +I+ ++ +P S+S A + L+ + P Sbjct: 519 DWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLSKE--AVSICKGLMTKHP 576 Query: 404 ANRMG-SYEGSNEIKQHPFFRGINWALVRGTAPPKLDAPLFSKDVGKG 264 R+G EG ++++H FFR I+W + ++ P K GKG Sbjct: 577 GKRLGCGPEGERDVREHAFFRRIDWEKLENR---EIQPPFKPKVCGKG 621
>KPCL_MOUSE (P23298) Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta)| (PKC-L) Length = 683 Score = 72.4 bits (176), Expect = 9e-13 Identities = 37/97 (38%), Positives = 57/97 (58%), Gaps = 4/97 (4%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWWA+G+LLYEML G+ PF + F IL+ ++ +P + AR ++ + ++P Sbjct: 536 DWWAMGVLLYEMLCGHAPFEAENEDDLFEAILNDEVVYPTWLHED--ARGILKSFMTKNP 593 Query: 404 ANRMGSYE--GSNEIKQHPFFRGINWALV--RGTAPP 306 R+GS G +EI +HPFF+ I+WA + R PP Sbjct: 594 TMRLGSLTQGGEHEILRHPFFKEIDWAQLNHRQLEPP 630
>AKT1_XENLA (Q98TY9) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase Akt-1) (Protein kinase B, alpha) (PKB alpha) (xAkt) Length = 481 Score = 72.4 bits (176), Expect = 9e-13 Identities = 37/86 (43%), Positives = 54/86 (62%), Gaps = 2/86 (2%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLP-ARQLIYRLLHRD 408 DWW LG+++YEM+ G PF + ++ F IL ++IRFP ++ LP A+ L+ LL +D Sbjct: 332 DWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTL---LPEAKSLLSGLLKKD 388 Query: 407 PANRM-GSYEGSNEIKQHPFFRGINW 333 P R+ G + + EI QH FF GI W Sbjct: 389 PKQRLGGGPDDAKEIMQHKFFAGIVW 414
>MAST1_RAT (Q810W7) Microtubule-associated serine/threonine-protein kinase 1| (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase) Length = 1570 Score = 72.0 bits (175), Expect = 1e-12 Identities = 36/85 (42%), Positives = 52/85 (61%), Gaps = 1/85 (1%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFP-ASISVSLPARQLIYRLLHRD 408 DWWA+GI+LYE L G PF G T + F ++ DI +P ++ A+ LI LL + Sbjct: 571 DWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDDILWPEGDEALPTDAQLLISSLLQTN 630 Query: 407 PANRMGSYEGSNEIKQHPFFRGINW 333 P R+G+ G+ E+KQH FFR ++W Sbjct: 631 PLVRLGA-GGAFEVKQHSFFRDLDW 654
>MAST1_HUMAN (Q9Y2H9) Microtubule-associated serine/threonine-protein kinase 1| (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase) Length = 1570 Score = 72.0 bits (175), Expect = 1e-12 Identities = 36/85 (42%), Positives = 52/85 (61%), Gaps = 1/85 (1%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFP-ASISVSLPARQLIYRLLHRD 408 DWWA+GI+LYE L G PF G T + F ++ DI +P ++ A+ LI LL + Sbjct: 569 DWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDDILWPEGDEALPTEAQLLISSLLQTN 628 Query: 407 PANRMGSYEGSNEIKQHPFFRGINW 333 P R+G+ G+ E+KQH FFR ++W Sbjct: 629 PLVRLGA-GGAFEVKQHSFFRDLDW 652
>MAST1_MOUSE (Q9R1L5) Microtubule-associated serine/threonine-protein kinase 1| (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase) Length = 1566 Score = 72.0 bits (175), Expect = 1e-12 Identities = 36/85 (42%), Positives = 52/85 (61%), Gaps = 1/85 (1%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFP-ASISVSLPARQLIYRLLHRD 408 DWWA+GI+LYE L G PF G T + F ++ DI +P ++ A+ LI LL + Sbjct: 570 DWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDDILWPEGDEALPTDAQLLISSLLQTN 629 Query: 407 PANRMGSYEGSNEIKQHPFFRGINW 333 P R+G+ G+ E+KQH FFR ++W Sbjct: 630 PLVRLGA-GGAFEVKQHSFFRDLDW 653
>KPCB_RABIT (P05772) Protein kinase C beta type (EC 2.7.11.13) (PKC-beta)| (PKC-B) Length = 670 Score = 72.0 bits (175), Expect = 1e-12 Identities = 35/85 (41%), Positives = 49/85 (57%), Gaps = 1/85 (1%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWWA G+LLYEML G PF G+ F +I+ ++ +P S+S A + L+ + P Sbjct: 522 DWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVA--ICKGLMTKHP 579 Query: 404 ANRMG-SYEGSNEIKQHPFFRGINW 333 R+G EG +IK H FFR I+W Sbjct: 580 GKRLGCGPEGERDIKDHAFFRYIDW 604
>AKT2_RAT (P47197) RAC-beta serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta) Length = 481 Score = 71.6 bits (174), Expect = 2e-12 Identities = 34/85 (40%), Positives = 51/85 (60%), Gaps = 1/85 (1%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW LG+++YEM+ G PF + +R F IL ++IRFP ++ A+ L+ LL +DP Sbjct: 332 DWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRTLGPE--AKSLLAGLLKKDP 389 Query: 404 ANRM-GSYEGSNEIKQHPFFRGINW 333 R+ G + E+ +H FF INW Sbjct: 390 KQRLGGGPSDAKEVMEHRFFLSINW 414
>AKT2_MOUSE (Q60823) RAC-beta serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta) Length = 481 Score = 71.6 bits (174), Expect = 2e-12 Identities = 34/85 (40%), Positives = 51/85 (60%), Gaps = 1/85 (1%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW LG+++YEM+ G PF + +R F IL ++IRFP ++ A+ L+ LL +DP Sbjct: 332 DWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRTLGPE--AKSLLAGLLKKDP 389 Query: 404 ANRM-GSYEGSNEIKQHPFFRGINW 333 R+ G + E+ +H FF INW Sbjct: 390 KQRLGGGPSDAKEVMEHRFFLSINW 414
>MRCKG_MOUSE (Q80UW5) Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1)| (CDC42-binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma Length = 1551 Score = 71.6 bits (174), Expect = 2e-12 Identities = 42/105 (40%), Positives = 66/105 (62%), Gaps = 6/105 (5%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANIL-HKD-IRFPASIS-VSLPARQLIYRLLH 414 DWW+LG+ YE+L+G TPF ++ T+ I+ H+D ++FPA ++ V A+ LI +LL Sbjct: 258 DWWSLGVCAYELLFGETPFYAESLVETYGKIMNHEDHLQFPADVTDVPASAQDLIRQLLC 317 Query: 413 RDPANRMGSYEGSNEIKQHPFFRGINW-ALVRGTAP--PKLDAPL 288 R R+G G ++ ++HPFF G++W L TAP P+L P+ Sbjct: 318 RQ-EERLGR-GGLDDFRKHPFFEGVDWERLATSTAPYIPELRGPM 360
>SGK1_RAT (Q06226) Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 1) Length = 430 Score = 71.6 bits (174), Expect = 2e-12 Identities = 35/84 (41%), Positives = 49/84 (58%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW LG +LYEMLYG PF + + NIL+K ++ +++ AR L+ LL +D Sbjct: 279 DWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLK---NITNSARHLLEGLLQKDR 335 Query: 404 ANRMGSYEGSNEIKQHPFFRGINW 333 R+G+ + EIK H FF INW Sbjct: 336 TKRLGAKDDFMEIKSHIFFSLINW 359
>MRCKB_HUMAN (Q9Y5S2) Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1)| (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta) Length = 1711 Score = 71.6 bits (174), Expect = 2e-12 Identities = 38/96 (39%), Positives = 57/96 (59%), Gaps = 3/96 (3%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIR--FPASIS-VSLPARQLIYRLLH 414 DWW+LG+ +YEMLYG TPF ++ T+ I++ + R FP+ ++ VS A+ LI RL+ Sbjct: 263 DWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHEERFQFPSHVTDVSEEAKDLIQRLI- 321 Query: 413 RDPANRMGSYEGSNEIKQHPFFRGINWALVRGTAPP 306 R+G G + K+H FF G+NW +R P Sbjct: 322 CSRERRLGQ-NGIEDFKKHAFFEGLNWENIRNLEAP 356
>MRCKB_RAT (Q7TT49) Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1)| (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta) Length = 1713 Score = 71.6 bits (174), Expect = 2e-12 Identities = 38/96 (39%), Positives = 57/96 (59%), Gaps = 3/96 (3%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIR--FPASIS-VSLPARQLIYRLLH 414 DWW+LG+ +YEMLYG TPF ++ T+ I++ + R FP+ ++ VS A+ LI RL+ Sbjct: 263 DWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHEERFQFPSHVTDVSEEAKDLIQRLI- 321 Query: 413 RDPANRMGSYEGSNEIKQHPFFRGINWALVRGTAPP 306 R+G G + K+H FF G+NW +R P Sbjct: 322 CSRERRLGQ-NGIEDFKKHAFFEGLNWENIRNLEAP 356
>MRCKB_MOUSE (Q7TT50) Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1)| (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta) Length = 1713 Score = 71.6 bits (174), Expect = 2e-12 Identities = 38/96 (39%), Positives = 57/96 (59%), Gaps = 3/96 (3%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIR--FPASIS-VSLPARQLIYRLLH 414 DWW+LG+ +YEMLYG TPF ++ T+ I++ + R FP+ ++ VS A+ LI RL+ Sbjct: 263 DWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHEERFQFPSHVTDVSEEAKDLIQRLI- 321 Query: 413 RDPANRMGSYEGSNEIKQHPFFRGINWALVRGTAPP 306 R+G G + K+H FF G+NW +R P Sbjct: 322 CSRERRLGQ-NGIEDFKKHAFFEGLNWENIRNLEAP 356
>AKT1_RAT (P47196) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase B) (PKB) Length = 480 Score = 71.6 bits (174), Expect = 2e-12 Identities = 35/85 (41%), Positives = 51/85 (60%), Gaps = 1/85 (1%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW LG+++YEM+ G PF + ++ F IL ++IRFP ++ A+ L+ LL +DP Sbjct: 331 DWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPE--AKSLLSGLLKKDP 388 Query: 404 ANRM-GSYEGSNEIKQHPFFRGINW 333 R+ G E + EI QH FF I W Sbjct: 389 TQRLGGGSEDAKEIMQHRFFANIVW 413
>AKT_MLVAT (P31748) AKT kinase transforming protein (EC 2.7.11.1)| Length = 501 Score = 71.6 bits (174), Expect = 2e-12 Identities = 35/85 (41%), Positives = 51/85 (60%), Gaps = 1/85 (1%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW LG+++YEM+ G PF + ++ F IL ++IRFP ++ A+ L+ LL +DP Sbjct: 352 DWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPE--AKSLLSGLLKKDP 409 Query: 404 ANRM-GSYEGSNEIKQHPFFRGINW 333 R+ G E + EI QH FF I W Sbjct: 410 TQRLGGGSEDAKEIMQHRFFANIVW 434
>KS6A4_HUMAN (O75676) Ribosomal protein S6 kinase alpha-4 (EC 2.7.11.1) (Nuclear| mitogen-and stress-activated protein kinase 2) (90 kDa ribosomal protein S6 kinase 4) (Ribosomal protein kinase B) (RSKB) Length = 772 Score = 71.2 bits (173), Expect = 2e-12 Identities = 37/101 (36%), Positives = 62/101 (61%), Gaps = 3/101 (2%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRF--PASISVSLPARQLIYRLLHR 411 DWW+LGILL+E+L G +PF + + T A + + ++ P + A+ L+ RLL + Sbjct: 220 DWWSLGILLFELLTGASPFTLEGERNTQAEVSRRILKCSPPFPPRIGPVAQDLLQRLLCK 279 Query: 410 DPANRMGS-YEGSNEIKQHPFFRGINWALVRGTAPPKLDAP 291 DP R+G+ +G+ E++ HPFF+G++W + A K+ AP Sbjct: 280 DPKKRLGAGPQGAQEVRNHPFFQGLDWVAL---AARKIPAP 317 Score = 41.6 bits (96), Expect = 0.002 Identities = 43/120 (35%), Positives = 59/120 (49%), Gaps = 9/120 (7%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKT---RQRTFANILHK--DIRF----PASISVSLPARQL 432 D W+LG++LY ML G PF+G + Q A I+ K + RF A VS A++L Sbjct: 591 DLWSLGVILYMMLSGQVPFQGASGQGGQSQAAEIMCKIREGRFSLDGEAWQGVSEEAKEL 650 Query: 431 IYRLLHRDPANRMGSYEGSNEIKQHPFFRGINWALVRGTAPPKLDAPLFSKDVGKGMGDA 252 + LL DPA R+ EG RG +W L G+A + PL + DV + G A Sbjct: 651 VRGLLTVDPAKRL-KLEG---------LRGSSW-LQDGSA--RSSPPLRTPDVLESSGPA 697
>KPC2_CAEEL (P90980) Protein kinase C-like 2 (EC 2.7.11.13) (PKC2)| Length = 682 Score = 71.2 bits (173), Expect = 2e-12 Identities = 39/99 (39%), Positives = 54/99 (54%), Gaps = 6/99 (6%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWWA G+LL+EML G PF G+ F I ++ +P S+S A L LL ++P Sbjct: 529 DWWAYGVLLFEMLAGQPPFDGEDEDELFTAITEHNVSYPKSLSKE--AVSLCKALLIKNP 586 Query: 404 ANRMG----SYEGSNEIKQHPFFRGINWALV--RGTAPP 306 + R+G S +IK+HPFFR I+W + R PP Sbjct: 587 SKRLGCTGDDESASRDIKEHPFFRRIDWFKIETRQIQPP 625
>PK2_DICDI (P28178) Protein kinase 2 (EC 2.7.11.1)| Length = 479 Score = 71.2 bits (173), Expect = 2e-12 Identities = 35/84 (41%), Positives = 52/84 (61%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW+LG LLYEML G PF + + IL+ +++ P IS A+ L+ LL R+ Sbjct: 332 DWWSLGTLLYEMLTGLPPFYSQNVSTMYQKILNGELKIPTYISPE--AKSLLEGLLTREV 389 Query: 404 ANRMGSYEGSNEIKQHPFFRGINW 333 R+G+ +G E+KQHP+F+ I+W Sbjct: 390 DKRLGT-KGGGEVKQHPWFKNIDW 412
>KS6B2_HUMAN (Q9UBS0) Ribosomal protein S6 kinase beta-2 (EC 2.7.11.1) (S6K2)| (70 kDa ribosomal protein S6 kinase 2) (p70-S6KB) (p70 ribosomal S6 kinase beta) (p70 S6Kbeta) (p70 S6 kinase beta) (S6K-beta) (p70-beta) (S6 kinase-related kinase) (SRK) (Serin Length = 482 Score = 70.9 bits (172), Expect = 3e-12 Identities = 32/85 (37%), Positives = 53/85 (62%), Gaps = 1/85 (1%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW+LG L+Y+ML G PF + R++T I+ + P ++ AR L+ + L R+P Sbjct: 251 DWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYLTPD--ARDLVKKFLKRNP 308 Query: 404 ANRMGSYEG-SNEIKQHPFFRGINW 333 + R+G G + ++++HPFFR +NW Sbjct: 309 SQRIGGGPGDAADVQRHPFFRHMNW 333
>KPCD_RAT (P09215) Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta)| Length = 673 Score = 70.9 bits (172), Expect = 3e-12 Identities = 37/95 (38%), Positives = 53/95 (55%), Gaps = 2/95 (2%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW+ G+LLYEML G +PF G F +I +P I+ ++ ++ +L RDP Sbjct: 528 DWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDTPHYPRWITKE--SKDIMEKLFERDP 585 Query: 404 ANRMGSYEGSNEIKQHPFFRGINWALV--RGTAPP 306 A R+G + I+ HPFF+ INW L+ R PP Sbjct: 586 AKRLGV---TGNIRLHPFFKTINWNLLEKRKVEPP 617
>AKT1_DROME (Q8INB9) RAC serine/threonine-protein kinase (EC 2.7.11.1)| (DRAC-PK) (Akt) (Dakt1) (Protein kinase B) (PKB) Length = 611 Score = 70.5 bits (171), Expect = 3e-12 Identities = 37/95 (38%), Positives = 54/95 (56%), Gaps = 2/95 (2%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW G+++YEM+ G PF + F IL ++++FP +I+ A+ L+ LL +DP Sbjct: 446 DWWGTGVVMYEMICGRLPFYNRDHDVLFTLILVEEVKFPRNITDE--AKNLLAGLLAKDP 503 Query: 404 ANRM-GSYEGSNEIKQHPFFRGINWA-LVRGTAPP 306 R+ G + EI+ HPFF INW LV PP Sbjct: 504 KKRLGGGKDDVKEIQAHPFFASINWTDLVLKKIPP 538
>KPCD_CANFA (Q5PU49) Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta)| Length = 674 Score = 70.5 bits (171), Expect = 3e-12 Identities = 37/95 (38%), Positives = 52/95 (54%), Gaps = 2/95 (2%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW+ G+LLYEML G +PF G F +I +P I+ ++ ++ +LL RD Sbjct: 528 DWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDTPHYPRWITKE--SKDILEKLLERDT 585 Query: 404 ANRMGSYEGSNEIKQHPFFRGINWALV--RGTAPP 306 R+G + IK HPFF+ INW L+ R PP Sbjct: 586 TKRLGV---TGNIKIHPFFKTINWTLLEKRAVEPP 617
>STK38_HUMAN (Q15208) Serine/threonine-protein kinase 38 (EC 2.7.11.1) (NDR1| protein kinase) (Nuclear Dbf2-related kinase 1) Length = 465 Score = 70.1 bits (170), Expect = 4e-12 Identities = 34/90 (37%), Positives = 56/90 (62%), Gaps = 2/90 (2%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILH--KDIRFPASISVSLPARQLIYRLLHR 411 DWW+LG+++YEML GY PF +T Q T+ +++ + + FP + +S A+ LI R Sbjct: 304 DWWSLGVIMYEMLIGYPPFCSETPQETYKKVMNWKETLTFPPEVPISEKAKDLILRFC-C 362 Query: 410 DPANRMGSYEGSNEIKQHPFFRGINWALVR 321 + +R+G+ G EIK + FF G++W +R Sbjct: 363 EWEHRIGA-PGVEEIKSNSFFEGVDWEHIR 391
>KPK1_ARATH (P42818) Serine/threonine-protein kinase AtPK1/AtPK6 (EC 2.7.11.1)| Length = 465 Score = 70.1 bits (170), Expect = 4e-12 Identities = 39/88 (44%), Positives = 55/88 (62%), Gaps = 4/88 (4%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPF---RGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLH 414 DWW++GILLYEML G PF +GK +Q+ I+ I+ P +S A ++ LL Sbjct: 313 DWWSVGILLYEMLTGKPPFLGSKGKIQQK----IVKDKIKLPQFLSNE--AHAILKGLLQ 366 Query: 413 RDPANRMGS-YEGSNEIKQHPFFRGINW 333 ++P R+GS G+ EIKQH +F+GINW Sbjct: 367 KEPERRLGSGLSGAEEIKQHKWFKGINW 394
>ROCK2_MOUSE (P70336) Rho-associated protein kinase 2 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 2) (p164 ROCK-2) Length = 1388 Score = 70.1 bits (170), Expect = 4e-12 Identities = 47/121 (38%), Positives = 64/121 (52%), Gaps = 4/121 (3%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANIL-HKD-IRFPASISVSLPARQLIYRLLHR 411 DWW++G+ L+EML G TPF + T++ I+ HK+ + FP +S A+ LI L Sbjct: 276 DWWSVGVFLFEMLVGDTPFYADSLVGTYSKIMDHKNSLCFPEDTEISKHAKNLICAFL-T 334 Query: 410 DPANRMGSYEGSNEIKQHPFFRG--INWALVRGTAPPKLDAPLFSKDVGKGMGDAAAADN 237 D R+G G EIKQHPFF+ NW +R TA P + P S D+ D D Sbjct: 335 DREVRLGR-NGVEEIKQHPFFKNDQWNWDNIRETAAPVV--PELSSDIDSSNFDDIEDDK 391 Query: 236 G 234 G Sbjct: 392 G 392
>ROCK2_BOVIN (Q28021) Rho-associated protein kinase 2 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 2) (p164 ROCK-2) Length = 1388 Score = 70.1 bits (170), Expect = 4e-12 Identities = 47/121 (38%), Positives = 64/121 (52%), Gaps = 4/121 (3%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANIL-HKD-IRFPASISVSLPARQLIYRLLHR 411 DWW++G+ L+EML G TPF + T++ I+ HK+ + FP +S A+ LI L Sbjct: 276 DWWSVGVFLFEMLVGDTPFYADSLVGTYSKIMDHKNSLCFPEDAEISKHAKNLICAFL-T 334 Query: 410 DPANRMGSYEGSNEIKQHPFFRG--INWALVRGTAPPKLDAPLFSKDVGKGMGDAAAADN 237 D R+G G EIKQHPFF+ NW +R TA P + P S D+ D D Sbjct: 335 DREVRLGR-NGVEEIKQHPFFKNDQWNWDNIRETAAPVV--PELSSDIDSSNFDDIEDDK 391 Query: 236 G 234 G Sbjct: 392 G 392
>KS6B2_MOUSE (Q9Z1M4) Ribosomal protein S6 kinase beta-2 (EC 2.7.11.1) (S6K-beta| 2) (70 kDa ribosomal protein S6 kinase 2) (p70-S6KB) (p70 ribosomal S6 kinase beta) (p70 S6Kbeta) (S6K2) Length = 485 Score = 70.1 bits (170), Expect = 4e-12 Identities = 37/96 (38%), Positives = 55/96 (57%), Gaps = 3/96 (3%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW+LG L+Y+ML G PF + R++T I+ + P ++ AR L + L R+P Sbjct: 251 DWWSLGALMYDMLTGSPPFTAENRKKTMDKIIKGKLVLPPYLTPD--ARDLAKKFLKRNP 308 Query: 404 ANRMGSYEG-SNEIKQHPFFRGINW--ALVRGTAPP 306 R+G G + ++++HPFFR INW L R PP Sbjct: 309 TQRIGGGLGDAADVQRHPFFRHINWDDLLARRVDPP 344
>KPCI_PONPY (Q5R4K9) Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota)| Length = 587 Score = 69.7 bits (169), Expect = 6e-12 Identities = 39/106 (36%), Positives = 58/106 (54%), Gaps = 13/106 (12%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPF---------RGKTRQRTFANILHKDIRFPASISVSLPARQL 432 DWWALG+L++EM+ G +PF T F IL K IR P S+SV A + Sbjct: 426 DWWALGVLMFEMMAGRSPFDIVGSSDNPDQNTEDYLFQVILEKQIRIPRSLSVK--AASV 483 Query: 431 IYRLLHRDPANRMGSY--EGSNEIKQHPFFRGINWALV--RGTAPP 306 + L++DP R+G + G +I+ HPFFR ++W ++ + PP Sbjct: 484 LKSFLNKDPKERLGCHPQTGFADIQGHPFFRNVDWDMMEQKQVVPP 529
>KPCI_HUMAN (P41743) Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota)| (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota) (PRKC-lambda/iota) Length = 587 Score = 69.7 bits (169), Expect = 6e-12 Identities = 39/106 (36%), Positives = 58/106 (54%), Gaps = 13/106 (12%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPF---------RGKTRQRTFANILHKDIRFPASISVSLPARQL 432 DWWALG+L++EM+ G +PF T F IL K IR P S+SV A + Sbjct: 426 DWWALGVLMFEMMAGRSPFDIVGSSDNPDQNTEDYLFQVILEKQIRIPRSLSVK--AASV 483 Query: 431 IYRLLHRDPANRMGSY--EGSNEIKQHPFFRGINWALV--RGTAPP 306 + L++DP R+G + G +I+ HPFFR ++W ++ + PP Sbjct: 484 LKSFLNKDPKERLGCHPQTGFADIQGHPFFRNVDWDMMEQKQVVPP 529
>KAPC_ASCSU (P49673) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) (PKA C) Length = 337 Score = 69.7 bits (169), Expect = 6e-12 Identities = 38/108 (35%), Positives = 59/108 (54%), Gaps = 3/108 (2%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW+LG+L+YEM+ G PFRGKT + I+ +RF S L A+ L+ +LL D Sbjct: 206 DWWSLGVLIYEMMIGIPPFRGKTLDEIYEKIILGKLRFTRSF--DLFAKDLVKKLLQVDR 263 Query: 404 ANRMGSY-EGSNEIKQHPFFRGINWALVRG--TAPPKLDAPLFSKDVG 270 R+G+ +G+ ++ H +F I+W V+ PP + + D G Sbjct: 264 TQRLGNQKDGAADVMNHKWFTDIDWDDVQNMKLTPPIIPTLYSNGDTG 311
>KPCI_MOUSE (Q62074) Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota)| (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota) Length = 586 Score = 69.7 bits (169), Expect = 6e-12 Identities = 39/106 (36%), Positives = 58/106 (54%), Gaps = 13/106 (12%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPF---------RGKTRQRTFANILHKDIRFPASISVSLPARQL 432 DWWALG+L++EM+ G +PF T F IL K IR P S+SV A + Sbjct: 425 DWWALGVLMFEMMAGRSPFDIVGSSDNPDQNTEDYLFQVILEKQIRIPRSLSVK--AASV 482 Query: 431 IYRLLHRDPANRMGSY--EGSNEIKQHPFFRGINWALV--RGTAPP 306 + L++DP R+G + G +I+ HPFFR ++W ++ + PP Sbjct: 483 LKSFLNKDPKERLGCHPQTGFADIQGHPFFRNVDWDMMEQKQVVPP 528
>KPCD_HUMAN (Q05655) Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta)| Length = 676 Score = 69.7 bits (169), Expect = 6e-12 Identities = 36/95 (37%), Positives = 52/95 (54%), Gaps = 2/95 (2%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW+ G+LLYEML G +PF G F +I +P I+ ++ ++ +L R+P Sbjct: 530 DWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDTPHYPRWITKE--SKDILEKLFEREP 587 Query: 404 ANRMGSYEGSNEIKQHPFFRGINWALV--RGTAPP 306 R+G + IK HPFF+ INW L+ R PP Sbjct: 588 TKRLGM---TGNIKIHPFFKTINWTLLEKRRLEPP 619
>KAPB_YEAST (P06245) cAMP-dependent protein kinase type 2 (EC 2.7.11.11) (PKA| 2) Length = 380 Score = 69.7 bits (169), Expect = 6e-12 Identities = 38/116 (32%), Positives = 62/116 (53%), Gaps = 1/116 (0%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW+LG+L+YEML GYTPF T +T+ IL + +P + L+ +L+ D Sbjct: 247 DWWSLGVLIYEMLAGYTPFYDTTPMKTYEKILQGKVVYPPYFHPDVV--DLLSKLITADL 304 Query: 404 ANRMGSYE-GSNEIKQHPFFRGINWALVRGTAPPKLDAPLFSKDVGKGMGDAAAAD 240 R+G+ + GS +IK HP+F + W + ++ P + + G+GD + D Sbjct: 305 TRRIGNLQSGSRDIKAHPWFSEVVWERL---LAKDIETP-YEPPITSGIGDTSLFD 356
>RIM15_YEAST (P43565) Serine/threonine-protein kinase RIM15 (EC 2.7.11.1)| Length = 1770 Score = 69.7 bits (169), Expect = 6e-12 Identities = 38/108 (35%), Positives = 60/108 (55%), Gaps = 10/108 (9%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASIS-------VSLPARQLIY 426 DWW++G + +E+L GY PF +T F IL I++P + ++ A+ LI Sbjct: 1170 DWWSVGCIFFELLLGYPPFHAETPDAVFKKILSGVIQWPEFKNEEEEREFLTPEAKDLIE 1229 Query: 425 RLLHRDPANRMGSYEGSNEIKQHPFFRGINWALV---RGTAPPKLDAP 291 +LL DPA R+G+ +G EIK HP+F+ ++W V + P +D P Sbjct: 1230 KLLVVDPAKRLGA-KGIQEIKDHPYFKNVDWDHVYDEEASFVPTIDNP 1276
>KAPCA_SHEEP (Q9MZD9) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 69.3 bits (168), Expect = 8e-12 Identities = 42/117 (35%), Positives = 61/117 (52%), Gaps = 1/117 (0%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWWALG+L+YEM GY PF + + I+ +RFP+ S L + L+ LL D Sbjct: 220 DWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDL--KDLLRNLLQVDL 277 Query: 404 ANRMGSYE-GSNEIKQHPFFRGINWALVRGTAPPKLDAPLFSKDVGKGMGDAAAADN 237 R G+ + G N+IK H +F +W + K++AP K KG GD + D+ Sbjct: 278 TKRFGNLKNGVNDIKNHKWFATTDWIAI---YQRKVEAPFIPK--FKGPGDTSNFDD 329
>KAPCA_RAT (P27791) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 69.3 bits (168), Expect = 8e-12 Identities = 42/117 (35%), Positives = 61/117 (52%), Gaps = 1/117 (0%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWWALG+L+YEM GY PF + + I+ +RFP+ S L + L+ LL D Sbjct: 220 DWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDL--KDLLRNLLQVDL 277 Query: 404 ANRMGSYE-GSNEIKQHPFFRGINWALVRGTAPPKLDAPLFSKDVGKGMGDAAAADN 237 R G+ + G N+IK H +F +W + K++AP K KG GD + D+ Sbjct: 278 TKRFGNLKNGVNDIKNHKWFATTDWIAI---YQRKVEAPFIPK--FKGPGDTSNFDD 329
>KAPCA_PIG (P36887) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 69.3 bits (168), Expect = 8e-12 Identities = 42/117 (35%), Positives = 61/117 (52%), Gaps = 1/117 (0%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWWALG+L+YEM GY PF + + I+ +RFP+ S L + L+ LL D Sbjct: 220 DWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDL--KDLLRNLLQVDL 277 Query: 404 ANRMGSYE-GSNEIKQHPFFRGINWALVRGTAPPKLDAPLFSKDVGKGMGDAAAADN 237 R G+ + G N+IK H +F +W + K++AP K KG GD + D+ Sbjct: 278 TKRFGNLKNGVNDIKNHKWFATTDWIAI---YQRKVEAPFIPK--FKGPGDTSNFDD 329
>KAPCA_MOUSE (P05132) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 69.3 bits (168), Expect = 8e-12 Identities = 42/117 (35%), Positives = 61/117 (52%), Gaps = 1/117 (0%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWWALG+L+YEM GY PF + + I+ +RFP+ S L + L+ LL D Sbjct: 220 DWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDL--KDLLRNLLQVDL 277 Query: 404 ANRMGSYE-GSNEIKQHPFFRGINWALVRGTAPPKLDAPLFSKDVGKGMGDAAAADN 237 R G+ + G N+IK H +F +W + K++AP K KG GD + D+ Sbjct: 278 TKRFGNLKNGVNDIKNHKWFATTDWIAI---YQRKVEAPFIPK--FKGPGDTSNFDD 329
>KAPCA_HUMAN (P17612) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 69.3 bits (168), Expect = 8e-12 Identities = 42/117 (35%), Positives = 61/117 (52%), Gaps = 1/117 (0%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWWALG+L+YEM GY PF + + I+ +RFP+ S L + L+ LL D Sbjct: 220 DWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDL--KDLLRNLLQVDL 277 Query: 404 ANRMGSYE-GSNEIKQHPFFRGINWALVRGTAPPKLDAPLFSKDVGKGMGDAAAADN 237 R G+ + G N+IK H +F +W + K++AP K KG GD + D+ Sbjct: 278 TKRFGNLKNGVNDIKNHKWFATTDWIAI---YQRKVEAPFIPK--FKGPGDTSNFDD 329
>KAPCA_CRIGR (P25321) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 69.3 bits (168), Expect = 8e-12 Identities = 42/117 (35%), Positives = 61/117 (52%), Gaps = 1/117 (0%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWWALG+L+YEM GY PF + + I+ +RFP+ S L + L+ LL D Sbjct: 220 DWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDL--KDLLRNLLQVDL 277 Query: 404 ANRMGSYE-GSNEIKQHPFFRGINWALVRGTAPPKLDAPLFSKDVGKGMGDAAAADN 237 R G+ + G N+IK H +F +W + K++AP K KG GD + D+ Sbjct: 278 TKRFGNLKNGVNDIKNHKWFATTDWIAI---YQRKVEAPFIPK--FKGPGDTSNFDD 329
>KAPCA_BOVIN (P00517) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 69.3 bits (168), Expect = 8e-12 Identities = 42/117 (35%), Positives = 61/117 (52%), Gaps = 1/117 (0%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWWALG+L+YEM GY PF + + I+ +RFP+ S L + L+ LL D Sbjct: 220 DWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDL--KDLLRNLLQVDL 277 Query: 404 ANRMGSYE-GSNEIKQHPFFRGINWALVRGTAPPKLDAPLFSKDVGKGMGDAAAADN 237 R G+ + G N+IK H +F +W + K++AP K KG GD + D+ Sbjct: 278 TKRFGNLKNGVNDIKNHKWFATTDWIAI---YQRKVEAPFIPK--FKGPGDTSNFDD 329
>DMPK_HUMAN (Q09013) Myotonin-protein kinase (EC 2.7.11.1) (Myotonic dystrophy| protein kinase) (MDPK) (DM-kinase) (DMK) (DMPK) (MT-PK) Length = 639 Score = 69.3 bits (168), Expect = 8e-12 Identities = 38/96 (39%), Positives = 52/96 (54%), Gaps = 3/96 (3%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILH--KDIRFP-ASISVSLPARQLIYRLLH 414 DWWALG+ YEM YG TPF + T+ I+H + + P V AR I RLL Sbjct: 270 DWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLVDEGVPEEARDFIQRLL- 328 Query: 413 RDPANRMGSYEGSNEIKQHPFFRGINWALVRGTAPP 306 P R+G G+ + + HPFF G++W +R + PP Sbjct: 329 CPPETRLGR-GGAGDFRTHPFFFGLDWDGLRDSVPP 363
>KAPCA_CANFA (Q8MJ44) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 349 Score = 69.3 bits (168), Expect = 8e-12 Identities = 42/117 (35%), Positives = 61/117 (52%), Gaps = 1/117 (0%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWWALG+L+YEM GY PF + + I+ +RFP+ S L + L+ LL D Sbjct: 219 DWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDL--KDLLRNLLQVDL 276 Query: 404 ANRMGSYE-GSNEIKQHPFFRGINWALVRGTAPPKLDAPLFSKDVGKGMGDAAAADN 237 R G+ + G N+IK H +F +W + K++AP K KG GD + D+ Sbjct: 277 TKRFGNLKNGVNDIKNHKWFATTDWIAI---YQRKVEAPFIPK--FKGPGDTSNFDD 328
>JIL1_DROME (Q9V3I5) Chromosomal serine/threonine-protein kinase JIL-1 (EC| 2.7.11.1) Length = 1207 Score = 69.3 bits (168), Expect = 8e-12 Identities = 34/93 (36%), Positives = 59/93 (63%), Gaps = 5/93 (5%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFR---GKTRQRTFANILHKDI-RFPASISVSLPARQLIYRLL 417 DWW++G+L +E+L G +PF G+ +Q + + K+ P+S S + AR + ++L Sbjct: 449 DWWSVGVLTFELLTGASPFATSDGQVQQSEISRRIQKEQPMIPSSFSAN--ARDFVLKML 506 Query: 416 HRDPANRMG-SYEGSNEIKQHPFFRGINWALVR 321 ++P R+G ++ ++EIK+HPFF GINW +R Sbjct: 507 EKNPKRRLGGNHRDASEIKEHPFFNGINWQELR 539
>KPCD_MOUSE (P28867) Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta)| Length = 674 Score = 69.3 bits (168), Expect = 8e-12 Identities = 36/95 (37%), Positives = 53/95 (55%), Gaps = 2/95 (2%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW+ G+LLYEML G +PF G F +I +P I+ ++ ++ +L RDP Sbjct: 528 DWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDTPHYPRWITKE--SKDIMEKLFERDP 585 Query: 404 ANRMGSYEGSNEIKQHPFFRGINWALV--RGTAPP 306 R+G + I+ HPFF+ INW+L+ R PP Sbjct: 586 DKRLGV---TGNIRIHPFFKTINWSLLEKRKVEPP 617
>AKT1_MOUSE (P31750) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (AKT1 kinase) (Protein kinase B) (PKB) (C-AKT) (Thymoma viral proto-oncogene) Length = 480 Score = 69.3 bits (168), Expect = 8e-12 Identities = 34/85 (40%), Positives = 50/85 (58%), Gaps = 1/85 (1%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW LG+++YEM+ G PF + ++ F IL ++I FP ++ A+ L+ LL +DP Sbjct: 331 DWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIAFPRTLGPE--AKSLLSGLLKKDP 388 Query: 404 ANRM-GSYEGSNEIKQHPFFRGINW 333 R+ G E + EI QH FF I W Sbjct: 389 TQRLGGGSEDAKEIMQHRFFANIVW 413
>MRCKG_HUMAN (Q6DT37) Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1)| (CDC42-binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma Length = 1551 Score = 68.9 bits (167), Expect = 1e-11 Identities = 41/105 (39%), Positives = 63/105 (60%), Gaps = 6/105 (5%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANIL-HKD-IRFPASI-SVSLPARQLIYRLLH 414 DWW+LG+ YE+L+G TPF ++ T+ I+ H+D ++FP + V A+ LI +LL Sbjct: 258 DWWSLGVCAYELLFGETPFYAESLVETYGKIMNHEDHLQFPPDVPDVPASAQDLIRQLLC 317 Query: 413 RDPANRMGSYEGSNEIKQHPFFRGINW-ALVRGTAP--PKLDAPL 288 R R+G G ++ + HPFF G++W L TAP P+L P+ Sbjct: 318 RQ-EERLGR-GGLDDFRNHPFFEGVDWERLASSTAPYIPELRGPM 360
>STK38_MOUSE (Q91VJ4) Serine/threonine-protein kinase 38 (EC 2.7.11.1) (NDR1| protein kinase) (Nuclear Dbf2-related kinase 1) Length = 465 Score = 68.9 bits (167), Expect = 1e-11 Identities = 35/90 (38%), Positives = 56/90 (62%), Gaps = 2/90 (2%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILH--KDIRFPASISVSLPARQLIYRLLHR 411 DWW+LG+++YEML GY PF +T Q T+ +++ + + FP + VS A+ LI R Sbjct: 304 DWWSLGVIMYEMLIGYPPFCSETPQETYKKVMNWKETLTFPPEVPVSEKAKGLILRFC-C 362 Query: 410 DPANRMGSYEGSNEIKQHPFFRGINWALVR 321 + +R+G+ G EIK + FF G++W +R Sbjct: 363 EWEHRIGA-PGVEEIKNNLFFEGVDWEHIR 391
>KPCZ_RAT (P09217) Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)| Length = 592 Score = 68.9 bits (167), Expect = 1e-11 Identities = 41/104 (39%), Positives = 57/104 (54%), Gaps = 11/104 (10%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPF-------RGKTRQRTFANILHKDIRFPASISVSLPARQLIY 426 DWWALG+L++EM+ G +PF T F IL K IR P +SV A ++ Sbjct: 433 DWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPRFLSVK--ASHVLK 490 Query: 425 RLLHRDPANRMG--SYEGSNEIKQHPFFRGINWALV--RGTAPP 306 L++DP R+G G ++IK H FFR I+W L+ + T PP Sbjct: 491 GFLNKDPKERLGCRPQTGFSDIKSHAFFRSIDWDLLEKKQTLPP 534
>KPCZ_MOUSE (Q02956) Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)| Length = 592 Score = 68.9 bits (167), Expect = 1e-11 Identities = 41/104 (39%), Positives = 57/104 (54%), Gaps = 11/104 (10%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPF-------RGKTRQRTFANILHKDIRFPASISVSLPARQLIY 426 DWWALG+L++EM+ G +PF T F IL K IR P +SV A ++ Sbjct: 433 DWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPRFLSVK--ASHVLK 490 Query: 425 RLLHRDPANRMG--SYEGSNEIKQHPFFRGINWALV--RGTAPP 306 L++DP R+G G ++IK H FFR I+W L+ + T PP Sbjct: 491 GFLNKDPKERLGCRPQTGFSDIKSHAFFRSIDWDLLEKKQTLPP 534
>PDPK1_DROME (Q9W0V1) 3-phosphoinositide-dependent protein kinase 1 (EC| 2.7.11.1) (dPDK-1) (Serine/threonine-protein kinase 61C) (dSTPK61) Length = 836 Score = 68.6 bits (166), Expect = 1e-11 Identities = 36/98 (36%), Positives = 51/98 (52%), Gaps = 3/98 (3%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 D WALG ++Y+M+ G PFRG F IL + FP A L+ +LL DP Sbjct: 492 DLWALGCIVYQMIAGLPPFRGSNDYVIFKEILDCAVDFPQGFDKD--AEDLVRKLLRVDP 549 Query: 404 ANRMGSYEG---SNEIKQHPFFRGINWALVRGTAPPKL 300 +R+G+ + I+ HPFF GI+W +R PP + Sbjct: 550 RDRLGAQDEFGYYESIRAHPFFAGIDWQTLRQQTPPPI 587
>KS6A5_CHICK (Q5F3L1) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1)| Length = 789 Score = 68.6 bits (166), Expect = 1e-11 Identities = 34/87 (39%), Positives = 54/87 (62%), Gaps = 3/87 (3%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRF--PASISVSLPARQLIYRLLHR 411 DWW++G+L+YE+L G +PF + + A I + ++ P +S ++ +I RLL + Sbjct: 227 DWWSVGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSALSKDIIQRLLMK 286 Query: 410 DPANRMG-SYEGSNEIKQHPFFRGINW 333 DP R+G ++EIKQHPFF+ INW Sbjct: 287 DPKKRLGCGPTDADEIKQHPFFQNINW 313 Score = 37.4 bits (85), Expect = 0.032 Identities = 26/73 (35%), Positives = 38/73 (52%), Gaps = 9/73 (12%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILH--KDIR-------FPASISVSLPARQL 432 D W+LG++LY ML G PF+ + + T + L K I+ A +VS A++L Sbjct: 594 DLWSLGVILYTMLSGQVPFQSQDKSLTCTSALEIMKKIKKGEFSFEGEAWKNVSEEAKEL 653 Query: 431 IYRLLHRDPANRM 393 I LL DP R+ Sbjct: 654 IQGLLTVDPNKRI 666
>PRKX_HUMAN (P51817) Serine/threonine-protein kinase PRKX (EC 2.7.11.1)| (Protein kinase PKX1) Length = 358 Score = 68.6 bits (166), Expect = 1e-11 Identities = 40/108 (37%), Positives = 58/108 (53%), Gaps = 1/108 (0%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWWALGIL++EML G+ PF + IL I FP + + + LI +LL D Sbjct: 226 DWWALGILIFEMLSGFPPFFDDNPFGIYQKILAGKIDFPRHLDFHV--KDLIKKLLVVDR 283 Query: 404 ANRMGSYE-GSNEIKQHPFFRGINWALVRGTAPPKLDAPLFSKDVGKG 264 R+G+ + G+N++K H +FR ++W V KL P+ K G G Sbjct: 284 TRRLGNMKNGANDVKHHRWFRSVDWEAV---PQRKLKPPIVPKIAGDG 328
>KPCL_RAT (Q64617) Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta)| (PKC-L) Length = 683 Score = 68.6 bits (166), Expect = 1e-11 Identities = 35/97 (36%), Positives = 55/97 (56%), Gaps = 4/97 (4%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWWA+G+LLYEML G+ PF + F IL+ ++ +P + A ++ + ++P Sbjct: 536 DWWAMGVLLYEMLCGHAPFEAENEDDLFEAILNDEVVYPTWLHED--ATGILKSFMTKNP 593 Query: 404 ANRMGSYE--GSNEIKQHPFFRGINWALV--RGTAPP 306 R+GS G +EI +HPFF+ I+W + R PP Sbjct: 594 TMRLGSLTQGGEHEILRHPFFKEIDWVQLNHRQLEPP 630
>PDPK1_RAT (O55173) 3-phosphoinositide-dependent protein kinase 1 (EC| 2.7.11.1) (Protein kinase B kinase) (PkB kinase) Length = 559 Score = 68.6 bits (166), Expect = 1e-11 Identities = 48/148 (32%), Positives = 66/148 (44%), Gaps = 6/148 (4%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 D WALG ++Y+++ G PFR F I+ + FP AR L+ +LL D Sbjct: 267 DLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPK--ARDLVEKLLVLDA 324 Query: 404 ANRMG--SYEGSNEIKQHPFFRGINWALVRGTAPPKLDA--PLFSKDVGKGMGDAAAADN 237 R+G EG +K HPFF I W + PPKL A P S+D G+ DN Sbjct: 325 TKRLGCEEMEGYGPLKAHPFFESITWENLHQQTPPKLTAYLPAMSEDDEDCYGN---YDN 381 Query: 236 GTDMF*TKKVDGKTCQR--CSISAVLAQ 159 F +V + C++ A L Q Sbjct: 382 LLSQFGCMQVSSSSSSHSLCAVDASLPQ 409
>KPC1_APLCA (Q16974) Calcium-dependent protein kinase C (EC 2.7.11.13) (APL I)| Length = 649 Score = 68.6 bits (166), Expect = 1e-11 Identities = 41/107 (38%), Positives = 54/107 (50%), Gaps = 3/107 (2%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWWA G+LLYEML G PF G+ + F +I ++ +P ++ S A L LL + P Sbjct: 501 DWWAYGVLLYEMLAGQPPFDGEDEEELFTSITDHNVSYPKAL--SREAVSLCKGLLTKTP 558 Query: 404 ANRMG-SYEGSNEIKQHPFFRGINWALV--RGTAPPKLDAPLFSKDV 273 A R+G G +IK FFR I W + R PP KDV Sbjct: 559 AKRLGCGPNGERDIKDRAFFRPIQWERIELREVQPPYKPRIKSRKDV 605
>ROCK2_HUMAN (O75116) Rho-associated protein kinase 2 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2) Length = 1388 Score = 68.6 bits (166), Expect = 1e-11 Identities = 46/121 (38%), Positives = 64/121 (52%), Gaps = 4/121 (3%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANIL-HKD-IRFPASISVSLPARQLIYRLLHR 411 DWW++G+ LYEML G TPF + T++ I+ HK+ + FP +S A+ LI L Sbjct: 276 DWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMDHKNSLCFPEDAEISKHAKNLICAFL-T 334 Query: 410 DPANRMGSYEGSNEIKQHPFFRG--INWALVRGTAPPKLDAPLFSKDVGKGMGDAAAADN 237 D R+G G EI+QHPFF+ +W +R TA P + P S D+ D D Sbjct: 335 DREVRLGR-NGVEEIRQHPFFKNDQWHWDNIRETAAPVV--PELSSDIDSSNFDDIEDDK 391 Query: 236 G 234 G Sbjct: 392 G 392
>KPC3_CAEEL (Q19266) Protein kinase C-like 3 (EC 2.7.11.13) (Atypical protein| kinase C-3) (aPKC3) Length = 597 Score = 68.2 bits (165), Expect = 2e-11 Identities = 41/108 (37%), Positives = 59/108 (54%), Gaps = 15/108 (13%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPF--------RGKTRQRTFANILHKDIRFPASISVSLPARQLI 429 DWWALG+L++EM+ G +PF T F IL + IR P S+SV A ++ Sbjct: 434 DWWALGVLMFEMMAGRSPFDIVGMQNSEENTEDYLFQIILERQIRIPRSLSVR--ASGIL 491 Query: 428 YRLLHRDPANRMGS----YEGSNEIKQHPFFRG-INWALV--RGTAPP 306 L++DP R+G EG ++K+H FFRG I+W + + APP Sbjct: 492 KGFLNKDPTERLGCKLDINEGLRDMKEHQFFRGFIDWEALEQKAVAPP 539
>KPCT_HUMAN (Q04759) Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)| Length = 706 Score = 68.2 bits (165), Expect = 2e-11 Identities = 33/84 (39%), Positives = 49/84 (58%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW+ G+LLYEML G +PF G+ + F +I + +P + A+ L+ +L R+P Sbjct: 561 DWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMDNPFYPRWLEKE--AKDLLVKLFVREP 618 Query: 404 ANRMGSYEGSNEIKQHPFFRGINW 333 R+G +I+QHP FR INW Sbjct: 619 EKRLGV---RGDIRQHPLFREINW 639
>PRKX_MOUSE (Q922R0) Serine/threonine-protein kinase PRKX (EC 2.7.11.1)| (PKA-related protein kinase) Length = 355 Score = 68.2 bits (165), Expect = 2e-11 Identities = 41/108 (37%), Positives = 59/108 (54%), Gaps = 1/108 (0%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWWALGIL++EML G+ PF + IL I FP + + ++ LI +LL D Sbjct: 223 DWWALGILIFEMLSGFPPFFDDNPFGIYQKILACKIDFPRQLDFT--SKDLIKKLLVVDR 280 Query: 404 ANRMGSYE-GSNEIKQHPFFRGINWALVRGTAPPKLDAPLFSKDVGKG 264 R+G+ + G+ +IK+H +FRG+ W V KL P+ K G G Sbjct: 281 TRRLGNMKNGAEDIKRHRWFRGVEWESV---PQRKLKPPIVPKLSGDG 325
>KAPC_DICDI (P34099) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) Length = 648 Score = 68.2 bits (165), Expect = 2e-11 Identities = 37/85 (43%), Positives = 48/85 (56%), Gaps = 1/85 (1%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWWALGIL++EML GY PF + IL I FP V A+ LI RLL D Sbjct: 513 DWWALGILIFEMLAGYPPFYDDDTFAIYNKILAGRITFPLGFDVD--AKDLIKRLLTADR 570 Query: 404 ANRMGSY-EGSNEIKQHPFFRGINW 333 R+G+ +G+ ++K H +F INW Sbjct: 571 TRRLGALKDGALDVKNHRWFSDINW 595
>DMPK_MOUSE (P54265) Myotonin-protein kinase (EC 2.7.11.1) (Myotonic dystrophy| protein kinase) (MDPK) (DM-kinase) (DMK) (DMPK) (MT-PK) Length = 631 Score = 68.2 bits (165), Expect = 2e-11 Identities = 38/96 (39%), Positives = 53/96 (55%), Gaps = 3/96 (3%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILH--KDIRFP-ASISVSLPARQLIYRLLH 414 DWWALG+ YEM YG TPF + T+A I+H + + P A V A+ LI LL Sbjct: 260 DWWALGVFAYEMFYGQTPFYADSTAETYAKIVHYREHLSLPLADTVVPEEAQDLIRGLL- 318 Query: 413 RDPANRMGSYEGSNEIKQHPFFRGINWALVRGTAPP 306 PA G+ + ++HPFF G++W +R + PP Sbjct: 319 -CPAEIRLGRGGAGDFQKHPFFFGLDWEGLRDSVPP 353
>KPCL_HUMAN (P24723) Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta)| (PKC-L) Length = 682 Score = 67.8 bits (164), Expect = 2e-11 Identities = 35/97 (36%), Positives = 55/97 (56%), Gaps = 4/97 (4%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWWA+G+LLYEML G+ PF + F IL+ ++ +P + A ++ + ++P Sbjct: 535 DWWAMGVLLYEMLCGHAPFEAENEDDLFEAILNDEVVYPTWLHED--ATGILKSFMTKNP 592 Query: 404 ANRMGSYE--GSNEIKQHPFFRGINWALV--RGTAPP 306 R+GS G + I +HPFF+ I+WA + R PP Sbjct: 593 TMRLGSLTQGGEHAILRHPFFKEIDWAQLNHRQIEPP 629
>KPC1B_CAEEL (P34885) Protein kinase C-like 1B (EC 2.7.11.13) (PKC1B)| Length = 707 Score = 67.8 bits (164), Expect = 2e-11 Identities = 41/118 (34%), Positives = 59/118 (50%), Gaps = 12/118 (10%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWWALG+L+YEM+ G PF F IL+ D+ +P + +S A ++ + ++ Sbjct: 559 DWWALGVLMYEMMAGQPPFEADNEDDLFEAILNDDVLYP--VWLSKEAVNILKAFMTKNA 616 Query: 404 ANRMG---SYEGSNEIKQHPFFRGINWALV--RGTAPP-------KLDAPLFSKDVGK 267 R+G S G + I+ HPFFR I+W + R PP K DA F D K Sbjct: 617 GKRLGCVVSQGGEDAIRAHPFFREIDWDALESRQVKPPFKPKIKSKRDANNFDSDFTK 674
>KPC2_DROME (P13677) Protein kinase C, eye isozyme (EC 2.7.11.13) (PKC)| (dPKC53E(EY)) (Protein INAC) (Inactivation no after-potential C protein) (Photoreceptor-specific PKC) (Eye-PKC) Length = 700 Score = 67.8 bits (164), Expect = 2e-11 Identities = 34/85 (40%), Positives = 44/85 (51%), Gaps = 1/85 (1%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW+ G+LL+E + G PF G F NI K FP SV A +I L + P Sbjct: 552 DWWSFGVLLFEFMAGQAPFEGDDETTVFRNIKDKKAVFPKHFSVE--AMDIITSFLTKKP 609 Query: 404 ANRMGSYE-GSNEIKQHPFFRGINW 333 NR+G+ EI HPFFR ++W Sbjct: 610 NNRLGAGRYARQEITTHPFFRNVDW 634
>AKT1_CAEEL (Q17941) Serine/threonine-protein kinase akt-1 (EC 2.7.11.1)| (Protein kinase B akt-1) (PKB akt-1) Length = 541 Score = 67.4 bits (163), Expect = 3e-11 Identities = 34/85 (40%), Positives = 51/85 (60%), Gaps = 1/85 (1%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW +G+++YEM+ G PF K + F I+ D+RFP+ +S AR L+ LL +DP Sbjct: 373 DWWGVGVVMYEMMCGRLPFYSKDHNKLFELIMAGDLRFPSKLSQE--ARTLLTGLLVKDP 430 Query: 404 ANRM-GSYEGSNEIKQHPFFRGINW 333 R+ G E + EI + FFR ++W Sbjct: 431 TQRLGGGPEDALEICRADFFRTVDW 455
>GRK6_HUMAN (P43250) G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK6) Length = 576 Score = 67.4 bits (163), Expect = 3e-11 Identities = 39/87 (44%), Positives = 52/87 (59%), Gaps = 3/87 (3%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPF--RGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHR 411 DWWALG LLYEM+ G +PF R K +R L K++ S S AR L +LL + Sbjct: 367 DWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEYSERFSPQARSLCSQLLCK 426 Query: 410 DPANRMGSYEGS-NEIKQHPFFRGINW 333 DPA R+G GS E+K+HP F+ +N+ Sbjct: 427 DPAERLGCRGGSAREVKEHPLFKKLNF 453
>PDPK1_MOUSE (Q9Z2A0) 3-phosphoinositide-dependent protein kinase 1 (EC| 2.7.11.1) (mPDK1) Length = 559 Score = 67.4 bits (163), Expect = 3e-11 Identities = 39/107 (36%), Positives = 52/107 (48%), Gaps = 4/107 (3%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 D WALG ++Y+++ G PFR F I+ + FP AR L+ +LL D Sbjct: 267 DLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYHFPEKFFPK--ARDLVEKLLVLDA 324 Query: 404 ANRMG--SYEGSNEIKQHPFFRGINWALVRGTAPPKLDA--PLFSKD 276 R+G EG +K HPFF I W + PPKL A P S+D Sbjct: 325 TKRLGCEEMEGYGPLKAHPFFETITWENLHQQTPPKLTAYLPAMSED 371
>KPCZ_RABIT (O19111) Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)| Length = 591 Score = 67.4 bits (163), Expect = 3e-11 Identities = 42/119 (35%), Positives = 58/119 (48%), Gaps = 9/119 (7%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPF-------RGKTRQRTFANILHKDIRFPASISVSLPARQLIY 426 DWWALG+L++EM+ G +PF T F IL K IR P +SV A ++ Sbjct: 432 DWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPRFLSVK--ASHVLK 489 Query: 425 RLLHRDPANRMG--SYEGSNEIKQHPFFRGINWALVRGTAPPKLDAPLFSKDVGKGMGD 255 L++DP R+G G ++IK H FFR I+W L+ P + D G D Sbjct: 490 GFLNKDPKERLGCRPQTGFSDIKSHAFFRSIDWDLLEKKQALPPFQPQITDDYGLDNSD 548
>KPC4_DROME (P83099) Putative protein kinase C, delta type homolog (EC| 2.7.11.13) Length = 643 Score = 67.4 bits (163), Expect = 3e-11 Identities = 38/96 (39%), Positives = 54/96 (56%), Gaps = 3/96 (3%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW+ G+LLYEML G +PF G F +I ++ FP + +S A ++ LL +D Sbjct: 496 DWWSFGVLLYEMLIGQSPFSGCDEDELFWSICNEIPWFP--VYISAEATGILKGLLEKDY 553 Query: 404 ANRMGS-YEGSNEIKQHPFFRGINWALV--RGTAPP 306 R+GS Y + +I H FFR I+W L+ R PP Sbjct: 554 TKRIGSQYSPAGDIADHIFFRPIDWGLLEKRQIEPP 589
>KPC1_CAEEL (P34722) Protein kinase C-like 1 (EC 2.7.11.13) (PKC)| (Tetradecanoyl phorbol acetate resistant protein 1) Length = 704 Score = 67.0 bits (162), Expect = 4e-11 Identities = 41/117 (35%), Positives = 62/117 (52%), Gaps = 1/117 (0%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 D+W+ G+L+YEML G +PF G+ F +IL++ FP +IS A + + L R+P Sbjct: 557 DFWSFGVLMYEMLVGQSPFHGEGEDELFDSILNERPYFPKTISKE--AAKCLSALFDRNP 614 Query: 404 ANRMGSYE-GSNEIKQHPFFRGINWALVRGTAPPKLDAPLFSKDVGKGMGDAAAADN 237 R+G E I+QH FFRG++W P P F ++ K DA+ D+ Sbjct: 615 NTRLGMPECPDGPIRQHCFFRGVDWKRFENRQVP----PPFKPNI-KSNSDASNFDD 666
>PDPK1_HUMAN (O15530) 3-phosphoinositide-dependent protein kinase 1 (EC| 2.7.11.1) (hPDK1) Length = 556 Score = 67.0 bits (162), Expect = 4e-11 Identities = 38/107 (35%), Positives = 52/107 (48%), Gaps = 4/107 (3%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 D WALG ++Y+++ G PFR F I+ + FP AR L+ +LL D Sbjct: 264 DLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPK--ARDLVEKLLVLDA 321 Query: 404 ANRMG--SYEGSNEIKQHPFFRGINWALVRGTAPPKLDA--PLFSKD 276 R+G EG +K HPFF + W + PPKL A P S+D Sbjct: 322 TKRLGCEEMEGYGPLKAHPFFESVTWENLHQQTPPKLTAYLPAMSED 368
>KPCZ_HUMAN (Q05513) Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)| Length = 592 Score = 67.0 bits (162), Expect = 4e-11 Identities = 38/96 (39%), Positives = 53/96 (55%), Gaps = 9/96 (9%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPF-------RGKTRQRTFANILHKDIRFPASISVSLPARQLIY 426 DWWALG+L++EM+ G +PF T F IL K IR P +SV A ++ Sbjct: 433 DWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPRFLSVK--ASHVLK 490 Query: 425 RLLHRDPANRMG--SYEGSNEIKQHPFFRGINWALV 324 L++DP R+G G ++IK H FFR I+W L+ Sbjct: 491 GFLNKDPKERLGCRPQTGFSDIKSHAFFRSIDWDLL 526
>KAPC_ENCCU (Q8SRK8) Probable cAMP-dependent protein kinase catalytic subunit| (EC 2.7.11.11) Length = 322 Score = 67.0 bits (162), Expect = 4e-11 Identities = 47/119 (39%), Positives = 63/119 (52%), Gaps = 8/119 (6%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 D+W LG+++YEML G PF + + IL ++ FP VS AR LI LL ++ Sbjct: 186 DYWGLGVMIYEMLCGDPPFYDSSADAIYHKILESNVVFPH--YVSPVARCLITGLLDKNR 243 Query: 404 ANRMGSYEGSNEIKQHPFFRGINWALV--RGTAPPKLDAP------LFSKDVGKGMGDA 252 A R+G+ +G EI HPFF+GI+W V R PP + P L S KG DA Sbjct: 244 ATRLGT-KGICEIMGHPFFKGIDWHEVESRRIEPPFIPNPNTVLSSLASSGELKGTDDA 301
>KPCG_BOVIN (P05128) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| (Fragment) Length = 682 Score = 67.0 bits (162), Expect = 4e-11 Identities = 34/85 (40%), Positives = 49/85 (57%), Gaps = 1/85 (1%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW+ G+LLYEML G PF G+ + F I+ + + +P S+S A + L + P Sbjct: 522 DWWSFGVLLYEMLAGQPPFDGEDEEELFQAIMEQTVTYPKSLSREAVA--ICKGFLTKHP 579 Query: 404 ANRMGS-YEGSNEIKQHPFFRGINW 333 A R+GS +G I+ H FFR I+W Sbjct: 580 AKRLGSGPDGEPTIRAHGFFRWIDW 604
>KAPCG_HUMAN (P22612) cAMP-dependent protein kinase, gamma-catalytic subunit (EC| 2.7.11.11) (PKA C-gamma) Length = 350 Score = 66.6 bits (161), Expect = 5e-11 Identities = 40/117 (34%), Positives = 60/117 (51%), Gaps = 1/117 (0%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWWALG+L+YEM G+ PF + + I+ +RFP+ +S L + L+ LL D Sbjct: 220 DWWALGVLIYEMAVGFPPFYADQPIQIYEKIVSGRVRFPSKLSSDL--KHLLRSLLQVDL 277 Query: 404 ANRMGSY-EGSNEIKQHPFFRGINWALVRGTAPPKLDAPLFSKDVGKGMGDAAAADN 237 R G+ G +IK H +F +W + K++AP K G GDA+ D+ Sbjct: 278 TKRFGNLRNGVGDIKNHKWFATTSWIAI---YEKKVEAPFIPKYTGP--GDASNFDD 329
>GRK6_MOUSE (O70293) G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK6) Length = 576 Score = 66.6 bits (161), Expect = 5e-11 Identities = 37/87 (42%), Positives = 52/87 (59%), Gaps = 3/87 (3%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPF--RGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHR 411 DWWALG LLYEM+ G +PF R K +R L K++ + S AR L +LL + Sbjct: 367 DWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVAEEYTDRFSSQARSLCSQLLSK 426 Query: 410 DPANRMGSY-EGSNEIKQHPFFRGINW 333 DPA R+G G+ E+K+HP F+ +N+ Sbjct: 427 DPAERLGCRGGGAREVKEHPLFKKLNF 453
>KPCT_MOUSE (Q02111) Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)| Length = 707 Score = 66.6 bits (161), Expect = 5e-11 Identities = 32/84 (38%), Positives = 49/84 (58%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW+ G+L+YEML G +PF G+ + F +I + +P + A+ L+ +L R+P Sbjct: 561 DWWSFGVLVYEMLIGQSPFHGQDEEELFHSIRMDNPFYPRWL--EREAKDLLVKLFVREP 618 Query: 404 ANRMGSYEGSNEIKQHPFFRGINW 333 R+G +I+QHP FR INW Sbjct: 619 EKRLGV---RGDIRQHPLFREINW 639
>MASTL_MOUSE (Q8C0P0) Microtubule-associated serine/threonine-protein kinase-like| (EC 2.7.11.1) Length = 865 Score = 66.6 bits (161), Expect = 5e-11 Identities = 37/99 (37%), Positives = 53/99 (53%), Gaps = 1/99 (1%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFP-ASISVSLPARQLIYRLLHRD 408 DWWALG+ L+E L G PF +T Q+ F NIL +DI +P +S A+ + LL D Sbjct: 746 DWWALGVCLFEFLTGIPPFNDETPQQVFQNILKRDIPWPEGEEKLSDNAQSAMDMLLTID 805 Query: 407 PANRMGSYEGSNEIKQHPFFRGINWALVRGTAPPKLDAP 291 + R G E+KQHP F ++W ++ P + P Sbjct: 806 DSKR----AGMRELKQHPLFSEVDWENLQHQTMPFVPQP 840
>KS6A5_HUMAN (O75582) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1) (Nuclear| mitogen-and stress-activated protein kinase 1) (90 kDa ribosomal protein S6 kinase 5) (RSK-like protein kinase) (RSKL) Length = 802 Score = 66.2 bits (160), Expect = 6e-11 Identities = 35/87 (40%), Positives = 53/87 (60%), Gaps = 3/87 (3%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRF--PASISVSLPARQLIYRLLHR 411 DWW+LG+L+YE+L G +PF + + A I + ++ P +S A+ LI RLL + Sbjct: 237 DWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSALAKDLIQRLLMK 296 Query: 410 DPANRMG-SYEGSNEIKQHPFFRGINW 333 DP R+G ++EIK+H FF+ INW Sbjct: 297 DPKKRLGCGPRDADEIKEHLFFQKINW 323 Score = 38.1 bits (87), Expect = 0.019 Identities = 26/73 (35%), Positives = 33/73 (45%), Gaps = 9/73 (12%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRT-------FANILHKDIRFPASI--SVSLPARQL 432 D W+LG++LY ML G PF+ R T I D F +VS A+ L Sbjct: 604 DLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNVSQEAKDL 663 Query: 431 IYRLLHRDPANRM 393 I LL DP R+ Sbjct: 664 IQGLLTVDPNKRL 676
>KPCG_HUMAN (P05129) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| Length = 697 Score = 66.2 bits (160), Expect = 6e-11 Identities = 37/95 (38%), Positives = 52/95 (54%), Gaps = 2/95 (2%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW+ G+LLYEML G PF G+ + F I+ + + +P S+S A + L + P Sbjct: 537 DWWSFGVLLYEMLAGQPPFDGEDEEELFQAIMEQTVTYPKSLSREAVA--ICKGFLTKHP 594 Query: 404 ANRMGS-YEGSNEIKQHPFFRGINW-ALVRGTAPP 306 R+GS +G I+ H FFR I+W L R PP Sbjct: 595 GKRLGSGPDGEPTIRAHGFFRWIDWERLERLEIPP 629
>KPK19_ARATH (Q39030) Serine/threonine-protein kinase AtPK19 (EC 2.7.11.1)| (Ribosomal-protein S6 kinase homolog) Length = 471 Score = 66.2 bits (160), Expect = 6e-11 Identities = 38/88 (43%), Positives = 54/88 (61%), Gaps = 4/88 (4%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPF---RGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLH 414 DWW++GILLYEML G PF +GK +Q+ I+ I+ P +S A L+ LL Sbjct: 319 DWWSVGILLYEMLTGKPPFLGSKGKIQQK----IVKDKIKLPQFLSNE--AHALLKGLLQ 372 Query: 413 RDPANRMGS-YEGSNEIKQHPFFRGINW 333 ++P R+GS G+ EIK+H +F+ INW Sbjct: 373 KEPERRLGSGPSGAEEIKKHKWFKAINW 400
>KAPB2_BOVIN (P24256) cAMP-dependent protein kinase, beta-2-catalytic subunit| (EC 2.7.11.11) (PKA C-beta-2) Length = 397 Score = 66.2 bits (160), Expect = 6e-11 Identities = 40/117 (34%), Positives = 61/117 (52%), Gaps = 1/117 (0%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWWALG+L+YEM GY PF + + I+ +RFP+ S L + L+ LL D Sbjct: 267 DWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDL--KDLLRNLLQVDL 324 Query: 404 ANRMGSYE-GSNEIKQHPFFRGINWALVRGTAPPKLDAPLFSKDVGKGMGDAAAADN 237 R G+ + G ++IK H +F +W + K++AP K +G GD + D+ Sbjct: 325 TKRFGNLKNGVSDIKTHKWFATTDWIAI---YQRKVEAPFIPK--FRGSGDTSNFDD 376
>KAPCB_RAT (P68182) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 66.2 bits (160), Expect = 6e-11 Identities = 40/117 (34%), Positives = 61/117 (52%), Gaps = 1/117 (0%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWWALG+L+YEM GY PF + + I+ +RFP+ S L + L+ LL D Sbjct: 220 DWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDL--KDLLRNLLQVDL 277 Query: 404 ANRMGSYE-GSNEIKQHPFFRGINWALVRGTAPPKLDAPLFSKDVGKGMGDAAAADN 237 R G+ + G ++IK H +F +W + K++AP K +G GD + D+ Sbjct: 278 TKRFGNLKNGVSDIKTHKWFATTDWIAI---YQRKVEAPFIPK--FRGSGDTSNFDD 329
>KAPCB_PIG (P05383) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 66.2 bits (160), Expect = 6e-11 Identities = 40/117 (34%), Positives = 61/117 (52%), Gaps = 1/117 (0%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWWALG+L+YEM GY PF + + I+ +RFP+ S L + L+ LL D Sbjct: 220 DWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDL--KDLLRNLLQVDL 277 Query: 404 ANRMGSYE-GSNEIKQHPFFRGINWALVRGTAPPKLDAPLFSKDVGKGMGDAAAADN 237 R G+ + G ++IK H +F +W + K++AP K +G GD + D+ Sbjct: 278 TKRFGNLKNGVSDIKTHKWFATTDWIAI---YQRKVEAPFIPK--FRGSGDTSNFDD 329
>KAPCB_MOUSE (P68181) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 66.2 bits (160), Expect = 6e-11 Identities = 40/117 (34%), Positives = 61/117 (52%), Gaps = 1/117 (0%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWWALG+L+YEM GY PF + + I+ +RFP+ S L + L+ LL D Sbjct: 220 DWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDL--KDLLRNLLQVDL 277 Query: 404 ANRMGSYE-GSNEIKQHPFFRGINWALVRGTAPPKLDAPLFSKDVGKGMGDAAAADN 237 R G+ + G ++IK H +F +W + K++AP K +G GD + D+ Sbjct: 278 TKRFGNLKNGVSDIKTHKWFATTDWIAI---YQRKVEAPFIPK--FRGSGDTSNFDD 329
>KAPCB_HUMAN (P22694) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 66.2 bits (160), Expect = 6e-11 Identities = 40/117 (34%), Positives = 61/117 (52%), Gaps = 1/117 (0%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWWALG+L+YEM GY PF + + I+ +RFP+ S L + L+ LL D Sbjct: 220 DWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDL--KDLLRNLLQVDL 277 Query: 404 ANRMGSYE-GSNEIKQHPFFRGINWALVRGTAPPKLDAPLFSKDVGKGMGDAAAADN 237 R G+ + G ++IK H +F +W + K++AP K +G GD + D+ Sbjct: 278 TKRFGNLKNGVSDIKTHKWFATTDWIAI---YQRKVEAPFIPK--FRGSGDTSNFDD 329
>KAPCB_CRIGR (P68180) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 66.2 bits (160), Expect = 6e-11 Identities = 40/117 (34%), Positives = 61/117 (52%), Gaps = 1/117 (0%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWWALG+L+YEM GY PF + + I+ +RFP+ S L + L+ LL D Sbjct: 220 DWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDL--KDLLRNLLQVDL 277 Query: 404 ANRMGSYE-GSNEIKQHPFFRGINWALVRGTAPPKLDAPLFSKDVGKGMGDAAAADN 237 R G+ + G ++IK H +F +W + K++AP K +G GD + D+ Sbjct: 278 TKRFGNLKNGVSDIKTHKWFATTDWIAI---YQRKVEAPFIPK--FRGSGDTSNFDD 329
>KAPB1_BOVIN (P05131) cAMP-dependent protein kinase, beta-1-catalytic subunit| (EC 2.7.11.11) (PKA C-beta-1) Length = 350 Score = 66.2 bits (160), Expect = 6e-11 Identities = 40/117 (34%), Positives = 61/117 (52%), Gaps = 1/117 (0%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWWALG+L+YEM GY PF + + I+ +RFP+ S L + L+ LL D Sbjct: 220 DWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDL--KDLLRNLLQVDL 277 Query: 404 ANRMGSYE-GSNEIKQHPFFRGINWALVRGTAPPKLDAPLFSKDVGKGMGDAAAADN 237 R G+ + G ++IK H +F +W + K++AP K +G GD + D+ Sbjct: 278 TKRFGNLKNGVSDIKTHKWFATTDWIAI---YQRKVEAPFIPK--FRGSGDTSNFDD 329
>MASTL_HUMAN (Q96GX5) Microtubule-associated serine/threonine-protein kinase-like| (EC 2.7.11.1) Length = 879 Score = 65.9 bits (159), Expect = 8e-11 Identities = 36/99 (36%), Positives = 52/99 (52%), Gaps = 1/99 (1%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFP-ASISVSLPARQLIYRLLHRD 408 DWWALG+ L+E L G PF +T Q+ F NIL +DI +P +S A+ + LL D Sbjct: 760 DWWALGVCLFEFLTGIPPFNDETPQQVFQNILKRDIPWPEGEEKLSDNAQSAVEILLTID 819 Query: 407 PANRMGSYEGSNEIKQHPFFRGINWALVRGTAPPKLDAP 291 R G E+K+HP F ++W ++ P + P Sbjct: 820 DTKR----AGMKELKRHPLFSDVDWENLQHQTMPFIPQP 854
>KPCG_RAT (P63319) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| Length = 697 Score = 65.5 bits (158), Expect = 1e-10 Identities = 33/85 (38%), Positives = 48/85 (56%), Gaps = 1/85 (1%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW+ G+LLYEML G PF G+ + F I+ + + +P S+S A + L + P Sbjct: 537 DWWSFGVLLYEMLAGQPPFDGEDEEELFQAIMEQTVTYPKSLSREAVA--ICKGFLTKHP 594 Query: 404 ANRMGS-YEGSNEIKQHPFFRGINW 333 R+GS +G I+ H FFR I+W Sbjct: 595 GKRLGSGPDGEPTIRAHGFFRWIDW 619
>KPCG_RABIT (P10829) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| (PKC-delta) Length = 697 Score = 65.5 bits (158), Expect = 1e-10 Identities = 33/85 (38%), Positives = 48/85 (56%), Gaps = 1/85 (1%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW+ G+LLYEML G PF G+ + F I+ + + +P S+S A + L + P Sbjct: 537 DWWSFGVLLYEMLAGQPPFDGEDEEELFQAIMEQTVTYPKSLSREAVA--ICKGFLTKHP 594 Query: 404 ANRMGS-YEGSNEIKQHPFFRGINW 333 R+GS +G I+ H FFR I+W Sbjct: 595 GKRLGSGPDGEPTIRAHGFFRWIDW 619
>KPCG_MOUSE (P63318) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| Length = 697 Score = 65.5 bits (158), Expect = 1e-10 Identities = 33/85 (38%), Positives = 48/85 (56%), Gaps = 1/85 (1%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW+ G+LLYEML G PF G+ + F I+ + + +P S+S A + L + P Sbjct: 537 DWWSFGVLLYEMLAGQPPFDGEDEEELFQAIMEQTVTYPKSLSREAVA--ICKGFLTKHP 594 Query: 404 ANRMGS-YEGSNEIKQHPFFRGINW 333 R+GS +G I+ H FFR I+W Sbjct: 595 GKRLGSGPDGEPTIRAHGFFRWIDW 619
>KPC1_NEUCR (P87253) Protein kinase C-like (EC 2.7.11.13)| Length = 1142 Score = 65.5 bits (158), Expect = 1e-10 Identities = 33/85 (38%), Positives = 49/85 (57%), Gaps = 1/85 (1%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWWA G+L+Y+ML +PFRG+ + IL + +P I + + ++ +LL R+P Sbjct: 999 DWWAFGVLIYQMLLQQSPFRGEDEDEIYDAILADEPLYP--IHMPRDSVSILQKLLTREP 1056 Query: 404 ANRMGS-YEGSNEIKQHPFFRGINW 333 R+GS + EI PFFR INW Sbjct: 1057 DQRLGSGPTDAQEIMSQPFFRNINW 1081
>ROCK1_RAT (Q63644) Rho-associated protein kinase 1 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (p150 RhoA-binding kinase ROK beta) (Liver regeneration-related protein LRRG199) Length = 1369 Score = 65.1 bits (157), Expect = 1e-10 Identities = 45/123 (36%), Positives = 63/123 (51%), Gaps = 4/123 (3%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANIL-HKD-IRFPASISVSLPARQLIYRLLHR 411 DWW++G+ LYEML G TPF + T++ I+ HK+ + FP +S A+ LI L Sbjct: 260 DWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFPDDNDISKEAKNLICAFL-T 318 Query: 410 DPANRMGSYEGSNEIKQHPFFRGINWA--LVRGTAPPKLDAPLFSKDVGKGMGDAAAADN 237 D R+G G EIK+H FF+ WA +R T P + P S D+ D D Sbjct: 319 DREVRLGR-NGVEEIKRHLFFKNDQWAWETLRDTVAPVV--PDLSSDIDTSNFDDLEEDK 375 Query: 236 GTD 228 G + Sbjct: 376 GDE 378
>KPC1_TRIRE (Q99014) Protein kinase C-like (EC 2.7.11.13)| Length = 1139 Score = 65.1 bits (157), Expect = 1e-10 Identities = 32/85 (37%), Positives = 49/85 (57%), Gaps = 1/85 (1%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWWA G+L+Y+ML +PFRG+ + IL + +P I + + ++ +LL R+P Sbjct: 996 DWWAFGVLIYQMLLQQSPFRGEDEDEIYDAILADEPLYP--IHMPRDSVSILQKLLTREP 1053 Query: 404 ANRMGS-YEGSNEIKQHPFFRGINW 333 R+GS + E+ PFFR INW Sbjct: 1054 DQRLGSGPTDAQEVMSQPFFRNINW 1078
>KPC1_COCHE (O42632) Protein kinase C-like (EC 2.7.11.13)| Length = 1174 Score = 65.1 bits (157), Expect = 1e-10 Identities = 33/85 (38%), Positives = 49/85 (57%), Gaps = 1/85 (1%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWWA G+L+Y+ML +PFRG+ + IL + +P I + + ++ +LL R+P Sbjct: 1031 DWWAFGVLIYQMLLQQSPFRGEDEDEIYDAILADEPLYP--IHMPRDSVSILQKLLTREP 1088 Query: 404 ANRMGS-YEGSNEIKQHPFFRGINW 333 R+GS + EI H FFR INW Sbjct: 1089 EMRLGSGPTDAQEIMSHAFFRNINW 1113
>KPCI_BRARE (Q90XF2) Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota)| (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota) (Heart and soul protein) Length = 588 Score = 65.1 bits (157), Expect = 1e-10 Identities = 38/106 (35%), Positives = 56/106 (52%), Gaps = 13/106 (12%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPF---------RGKTRQRTFANILHKDIRFPASISVSLPARQL 432 DWWALG+L++EM+ G +PF T F IL K IR P S+SV A + Sbjct: 427 DWWALGVLMFEMMAGRSPFDIVGSSDNPDQNTEDYLFQVILEKQIRIPRSLSVK--AASV 484 Query: 431 IYRLLHRDPANRMGSY--EGSNEIKQHPFFRGINWALV--RGTAPP 306 + L+++ R+G + G +I HPFFR ++W L+ + PP Sbjct: 485 LKGFLNKESKERLGCHPQTGFADIMAHPFFRNVDWDLMEQKQVVPP 530
>ROCK1_RABIT (O77819) Rho-associated protein kinase 1 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (cAMP-dependent protein kinase ROCK-I) (CePKA) (Corneal epithelial Rho-associated-Ser/Thr kinase 1) (HEB Length = 1354 Score = 65.1 bits (157), Expect = 1e-10 Identities = 45/123 (36%), Positives = 63/123 (51%), Gaps = 4/123 (3%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANIL-HKD-IRFPASISVSLPARQLIYRLLHR 411 DWW++G+ LYEML G TPF + T++ I+ HK+ + FP +S A+ LI L Sbjct: 260 DWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFPDDNDISKEAKNLICAFL-T 318 Query: 410 DPANRMGSYEGSNEIKQHPFFRGINWA--LVRGTAPPKLDAPLFSKDVGKGMGDAAAADN 237 D R+G G EIK+H FF+ WA +R T P + P S D+ D D Sbjct: 319 DREVRLGR-NGVEEIKRHLFFKNDQWAWETLRDTVAPVV--PDLSSDIDTSNFDDLEEDK 375 Query: 236 GTD 228 G + Sbjct: 376 GDE 378
>ROCK1_MOUSE (P70335) Rho-associated protein kinase 1 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) Length = 1354 Score = 65.1 bits (157), Expect = 1e-10 Identities = 45/123 (36%), Positives = 63/123 (51%), Gaps = 4/123 (3%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANIL-HKD-IRFPASISVSLPARQLIYRLLHR 411 DWW++G+ LYEML G TPF + T++ I+ HK+ + FP +S A+ LI L Sbjct: 260 DWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFPDDNDISKEAKNLICAFL-T 318 Query: 410 DPANRMGSYEGSNEIKQHPFFRGINWA--LVRGTAPPKLDAPLFSKDVGKGMGDAAAADN 237 D R+G G EIK+H FF+ WA +R T P + P S D+ D D Sbjct: 319 DREVRLGR-NGVEEIKRHLFFKNDQWAWETLRDTVAPVV--PDLSSDIDTSNFDDLEEDK 375 Query: 236 GTD 228 G + Sbjct: 376 GDE 378
>ROCK1_HUMAN (Q13464) Rho-associated protein kinase 1 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen) Length = 1354 Score = 65.1 bits (157), Expect = 1e-10 Identities = 45/123 (36%), Positives = 63/123 (51%), Gaps = 4/123 (3%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANIL-HKD-IRFPASISVSLPARQLIYRLLHR 411 DWW++G+ LYEML G TPF + T++ I+ HK+ + FP +S A+ LI L Sbjct: 260 DWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFPDDNDISKEAKNLICAFL-T 318 Query: 410 DPANRMGSYEGSNEIKQHPFFRGINWA--LVRGTAPPKLDAPLFSKDVGKGMGDAAAADN 237 D R+G G EIK+H FF+ WA +R T P + P S D+ D D Sbjct: 319 DREVRLGR-NGVEEIKRHLFFKNDQWAWETLRDTVAPVV--PDLSSDIDTSNFDDLEEDK 375 Query: 236 GTD 228 G + Sbjct: 376 GEE 378
>KGP1A_RABIT (O77676) cGMP-dependent protein kinase 1, alpha isozyme (EC| 2.7.11.12) (CGK 1 alpha) (cGKI-alpha) Length = 670 Score = 64.7 bits (156), Expect = 2e-10 Identities = 38/99 (38%), Positives = 58/99 (58%), Gaps = 4/99 (4%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILH--KDIRFPASISVSLPARQLIYRLLHR 411 D+W+LGIL+YE+L G PF G +T+ IL I FP I+ + A LI +L Sbjct: 539 DYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKN--AANLIKKLCRD 596 Query: 410 DPANRMGSYE-GSNEIKQHPFFRGINW-ALVRGTAPPKL 300 +P+ R+G+ + G +I++H +F G NW L +GT P + Sbjct: 597 NPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPI 635
>KGP1A_HUMAN (Q13976) cGMP-dependent protein kinase 1, alpha isozyme (EC| 2.7.11.12) (CGK 1 alpha) (cGKI-alpha) Length = 670 Score = 64.7 bits (156), Expect = 2e-10 Identities = 38/99 (38%), Positives = 58/99 (58%), Gaps = 4/99 (4%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILH--KDIRFPASISVSLPARQLIYRLLHR 411 D+W+LGIL+YE+L G PF G +T+ IL I FP I+ + A LI +L Sbjct: 539 DYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKN--AANLIKKLCRD 596 Query: 410 DPANRMGSYE-GSNEIKQHPFFRGINW-ALVRGTAPPKL 300 +P+ R+G+ + G +I++H +F G NW L +GT P + Sbjct: 597 NPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPI 635
>KGP1A_BOVIN (P00516) cGMP-dependent protein kinase 1, alpha isozyme (EC| 2.7.11.12) (CGK 1 alpha) (cGKI-alpha) Length = 670 Score = 64.7 bits (156), Expect = 2e-10 Identities = 38/99 (38%), Positives = 58/99 (58%), Gaps = 4/99 (4%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILH--KDIRFPASISVSLPARQLIYRLLHR 411 D+W+LGIL+YE+L G PF G +T+ IL I FP I+ + A LI +L Sbjct: 539 DYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKN--AANLIKKLCRD 596 Query: 410 DPANRMGSYE-GSNEIKQHPFFRGINW-ALVRGTAPPKL 300 +P+ R+G+ + G +I++H +F G NW L +GT P + Sbjct: 597 NPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPI 635
>KGP1B_MOUSE (Q9Z0Z0) cGMP-dependent protein kinase 1, beta isozyme (EC| 2.7.11.12) (cGK 1 beta) (cGKI-beta) Length = 686 Score = 64.7 bits (156), Expect = 2e-10 Identities = 38/99 (38%), Positives = 58/99 (58%), Gaps = 4/99 (4%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILH--KDIRFPASISVSLPARQLIYRLLHR 411 D+W+LGIL+YE+L G PF G +T+ IL I FP I+ + A LI +L Sbjct: 555 DYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKN--AANLIKKLCRD 612 Query: 410 DPANRMGSYE-GSNEIKQHPFFRGINW-ALVRGTAPPKL 300 +P+ R+G+ + G +I++H +F G NW L +GT P + Sbjct: 613 NPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPI 651
>KGP1B_HUMAN (P14619) cGMP-dependent protein kinase 1, beta isozyme (EC| 2.7.11.12) (cGK 1 beta) (cGKI-beta) Length = 686 Score = 64.7 bits (156), Expect = 2e-10 Identities = 38/99 (38%), Positives = 58/99 (58%), Gaps = 4/99 (4%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILH--KDIRFPASISVSLPARQLIYRLLHR 411 D+W+LGIL+YE+L G PF G +T+ IL I FP I+ + A LI +L Sbjct: 555 DYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKN--AANLIKKLCRD 612 Query: 410 DPANRMGSYE-GSNEIKQHPFFRGINW-ALVRGTAPPKL 300 +P+ R+G+ + G +I++H +F G NW L +GT P + Sbjct: 613 NPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPI 651
>KGP1B_BOVIN (P21136) cGMP-dependent protein kinase 1, beta isozyme (EC| 2.7.11.12) (cGK 1 beta) (cGKI-beta) Length = 686 Score = 64.7 bits (156), Expect = 2e-10 Identities = 38/99 (38%), Positives = 58/99 (58%), Gaps = 4/99 (4%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILH--KDIRFPASISVSLPARQLIYRLLHR 411 D+W+LGIL+YE+L G PF G +T+ IL I FP I+ + A LI +L Sbjct: 555 DYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKN--AANLIKKLCRD 612 Query: 410 DPANRMGSYE-GSNEIKQHPFFRGINW-ALVRGTAPPKL 300 +P+ R+G+ + G +I++H +F G NW L +GT P + Sbjct: 613 NPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPI 651
>KAPC_DROME (P12370) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) (PKA C) Length = 352 Score = 64.3 bits (155), Expect = 2e-10 Identities = 39/117 (33%), Positives = 59/117 (50%), Gaps = 1/117 (0%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWWALG+L+YEM GY PF + + I+ +RFP+ L + L+ LL D Sbjct: 222 DWWALGVLVYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFGSDL--KDLLRNLLQVDL 279 Query: 404 ANRMGSYE-GSNEIKQHPFFRGINWALVRGTAPPKLDAPLFSKDVGKGMGDAAAADN 237 R G+ + G N+IK +F +W + K++AP + KG GD + D+ Sbjct: 280 TKRYGNLKAGVNDIKNQKWFASTDWIAI---FQKKIEAPFIPR--CKGPGDTSNFDD 331
>KPC1_ASPNG (Q00078) Protein kinase C-like (EC 2.7.11.13)| Length = 1096 Score = 64.3 bits (155), Expect = 2e-10 Identities = 32/85 (37%), Positives = 49/85 (57%), Gaps = 1/85 (1%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWWA G+L+Y+ML +PFRG+ + IL + +P I + + ++ +LL R+P Sbjct: 953 DWWAFGVLIYQMLLQQSPFRGEDEDEIYDAILADEPLYP--IHMPRDSVSILQKLLTREP 1010 Query: 404 ANRMGS-YEGSNEIKQHPFFRGINW 333 R+GS + E+ H FFR INW Sbjct: 1011 ELRLGSGPTDAQEVMSHAFFRNINW 1035
>GRK6_RAT (P97711) G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK6) Length = 576 Score = 64.3 bits (155), Expect = 2e-10 Identities = 36/87 (41%), Positives = 52/87 (59%), Gaps = 3/87 (3%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPF--RGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHR 411 DWWALG LLYEM+ G +PF R K +R L K++ + S AR L +L ++ Sbjct: 367 DWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVAEEYTDRFSPQARSLCSQLPNK 426 Query: 410 DPANRMGSY-EGSNEIKQHPFFRGINW 333 DPA R+G G+ E+K+HP F+ +N+ Sbjct: 427 DPAERLGCRGGGAREVKEHPLFKKLNF 453
>KS6A_CAEEL (Q21734) Putative ribosomal protein S6 kinase alpha (EC 2.7.11.1)| Length = 784 Score = 64.3 bits (155), Expect = 2e-10 Identities = 44/135 (32%), Positives = 69/135 (51%), Gaps = 14/135 (10%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 D+W+LG+L++EML G+ PF+G+ R T IL + P ++ A+ L+ L R+ Sbjct: 286 DFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILKAKLSMPHFLTQE--AQSLLRALFKRNS 343 Query: 404 ANRMGS-YEGSNEIKQHPFFRGINWA--LVRGTAPPKLDA-----------PLFSKDVGK 267 NR+G+ +G EIK+H FF I++ L + PP A P F+K K Sbjct: 344 QNRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEIDPPFKPALSTVDSTSYFDPEFTKRTPK 403 Query: 266 GMGDAAAADNGTDMF 222 A+ NG ++F Sbjct: 404 DSPALPASANGHEIF 418 Score = 33.9 bits (76), Expect = 0.35 Identities = 32/112 (28%), Positives = 50/112 (44%), Gaps = 6/112 (5%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHK------DIRFPASISVSLPARQLIYR 423 D W+LG+LL+ ML G TPF T IL + + P ++S A+ L+ + Sbjct: 633 DVWSLGVLLHTMLTGCTPF-AMGPNDTPDQILQRVGDGKISMTHPVWDTISDEAKDLVRK 691 Query: 422 LLHRDPANRMGSYEGSNEIKQHPFFRGINWALVRGTAPPKLDAPLFSKDVGK 267 +L DP R+ + + QH W + P D P+ S+ VG+ Sbjct: 692 MLDVDPNRRV----TAKQALQH------KWIGQKEALP---DRPIQSEQVGE 730
>GRK2_CAEEL (Q09639) G protein-coupled receptor kinase 2 (EC 2.7.11.16)| Length = 707 Score = 64.3 bits (155), Expect = 2e-10 Identities = 37/99 (37%), Positives = 57/99 (57%), Gaps = 6/99 (6%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFR---GKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLH 414 DW++LG +LY++L G++PFR K + L +DI P + +S R L+ LL Sbjct: 374 DWFSLGCMLYKLLKGHSPFRQHKSKDKNEIDKMTLTQDIELP-NEGLSKDCRDLLEGLLK 432 Query: 413 RDPANRMGSY-EGSNEIKQHPFFRGINWALV--RGTAPP 306 RD +R+G +G E+K+HPFF+ ++W V R PP Sbjct: 433 RDVPDRLGCRGKGPTEVKEHPFFKDVDWQTVYLRRMTPP 471
>KS6A5_PONPY (Q5R4K3) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1)| Length = 802 Score = 64.3 bits (155), Expect = 2e-10 Identities = 34/87 (39%), Positives = 52/87 (59%), Gaps = 3/87 (3%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRF--PASISVSLPARQLIYRLLHR 411 DWW+LG+L+YE+L G +PF + + A I + ++ P +S A+ LI LL + Sbjct: 237 DWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSALAKDLIQHLLMK 296 Query: 410 DPANRMG-SYEGSNEIKQHPFFRGINW 333 DP R+G ++EIK+H FF+ INW Sbjct: 297 DPKKRLGCGPRDADEIKEHLFFQKINW 323 Score = 38.1 bits (87), Expect = 0.019 Identities = 26/73 (35%), Positives = 33/73 (45%), Gaps = 9/73 (12%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRT-------FANILHKDIRFPASI--SVSLPARQL 432 D W+LG++LY ML G PF+ R T I D F +VS A+ L Sbjct: 604 DLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNVSQEAKDL 663 Query: 431 IYRLLHRDPANRM 393 I LL DP R+ Sbjct: 664 IQGLLTVDPNKRL 676
>CBK1_EMENI (P0C1B1) Serine/threonine-protein kinase cbk1 (EC 2.7.11.1)| Length = 884 Score = 64.3 bits (155), Expect = 2e-10 Identities = 42/132 (31%), Positives = 57/132 (43%), Gaps = 39/132 (29%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANI------LHKDIRFPASISVSLPARQLIYR 423 DWW+LG++LYE LYG+TPF + R +T I L+ + P VS A +I Sbjct: 635 DWWSLGVILYECLYGFTPFASEDRHQTKLKIHRHLQTLYFPVHRPTDKLVSADAIDVINS 694 Query: 422 LLHR--------------------------DPANRMGSYEG-------SNEIKQHPFFRG 342 LL P + SY+G + +IK H FFRG Sbjct: 695 LLQEKEFRLSSPKYKQNDAISSKPAKCSFYKPDSSNPSYQGHYVYPDDATDIKSHRFFRG 754 Query: 341 INWALVRGTAPP 306 INW + T+PP Sbjct: 755 INWEQIHRTSPP 766
>ARBK2_RAT (P26819) Beta-adrenergic receptor kinase 2 (EC 2.7.11.15)| (Beta-ARK-2) (G-protein-coupled receptor kinase 3) Length = 688 Score = 64.3 bits (155), Expect = 2e-10 Identities = 39/103 (37%), Positives = 61/103 (59%), Gaps = 10/103 (9%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFR-GKTRQRTFANILHKDIRFPASISVSLP------ARQLIY 426 DW++LG +L+++L G++PFR KT+ + H+ R +++V LP R L+ Sbjct: 373 DWFSLGCMLFKLLRGHSPFRQHKTKDK------HEIDRMTLTVNVQLPDAFSPELRSLLE 426 Query: 425 RLLHRDPANRMGSY-EGSNEIKQHPFFRGINWALV--RGTAPP 306 LL RD + R+G Y G+ E+K+H FF+GI+W V R PP Sbjct: 427 GLLQRDVSQRLGCYGGGARELKEHIFFKGIDWQYVYLRKYPPP 469
>KPC2_APLCA (Q16975) Calcium-independent protein kinase C (EC 2.7.11.13) (APL| II) Length = 743 Score = 63.9 bits (154), Expect = 3e-10 Identities = 41/116 (35%), Positives = 61/116 (52%), Gaps = 13/116 (11%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWWALG+L+YEM+ G PF F +ILH D+ +P + +S A ++ + ++P Sbjct: 584 DWWALGVLMYEMMAGQPPFEADNEDDLFESILHDDVLYP--VWLSKEAVSILKGFMTKNP 641 Query: 404 ANRMG--SYEGSNE-IKQHPFF-RGINWALV--RGTAPP-------KLDAPLFSKD 276 A R+G + +G + I HPFF I+W + R PP K DA F +D Sbjct: 642 AKRLGCVTTQGCEKAILVHPFFHEKIDWEALEQRKVKPPFKPKIKNKTDANNFDRD 697
>KPC1_CANAL (P43057) Protein kinase C-like 1 (EC 2.7.11.13) (PKC 1)| Length = 1097 Score = 63.5 bits (153), Expect = 4e-10 Identities = 30/85 (35%), Positives = 53/85 (62%), Gaps = 1/85 (1%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWWA G+LL++ML +PF+G F I + ++++P I++S ++ LL +DP Sbjct: 952 DWWAFGVLLFQMLLCQSPFKGDDEDDIFNAIENDEVKYP--INLSRQTVLVLQALLTKDP 1009 Query: 404 ANRMGS-YEGSNEIKQHPFFRGINW 333 + R+GS + + EI +HP+F +N+ Sbjct: 1010 SQRLGSGPKDAEEIMEHPYFHDVNF 1034
>KPC1_LYTPI (Q25378) Protein kinase C (EC 2.7.11.13)| Length = 658 Score = 63.5 bits (153), Expect = 4e-10 Identities = 33/85 (38%), Positives = 47/85 (55%), Gaps = 1/85 (1%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWWA G+LLYEML G PF G+ F +I+ +P S+S + + L + P Sbjct: 506 DWWAFGVLLYEMLAGQPPFDGEDEDELFQSIMEHVPSYPK--SMSRESVTMCKGFLTKHP 563 Query: 404 ANRMGS-YEGSNEIKQHPFFRGINW 333 R+GS G +I++H FFR I+W Sbjct: 564 GKRLGSGPTGEQDIREHQFFRRIDW 588
>KAPC_CAEEL (P21137) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) (PKA C) Length = 404 Score = 63.5 bits (153), Expect = 4e-10 Identities = 37/108 (34%), Positives = 54/108 (50%), Gaps = 1/108 (0%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWWALG+L+YEM GY PF + + I+ ++FP+ S L + L+ LL D Sbjct: 258 DWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVKFPSHFSNEL--KDLLKNLLQVDL 315 Query: 404 ANRMGSYE-GSNEIKQHPFFRGINWALVRGTAPPKLDAPLFSKDVGKG 264 R G+ + G +IK H +F +W + K+ P FSK G Sbjct: 316 TKRYGNLKNGVADIKNHKWFGSTDWIAI---YQKKITPPSFSKGESNG 360
>KDC2_DROME (P16912) Protein kinase DC2 (EC 2.7.11.1)| Length = 583 Score = 63.5 bits (153), Expect = 4e-10 Identities = 32/85 (37%), Positives = 51/85 (60%), Gaps = 1/85 (1%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWWALG+L+YEML GY PF + + IL I + + A+ LI +LL D Sbjct: 451 DWWALGVLIYEMLVGYPPFYDEQPFGIYEKILSGKIEWERHMDPI--AKDLIKKLLVNDR 508 Query: 404 ANRMGSYE-GSNEIKQHPFFRGINW 333 R+G+ + G++++K+H +F+ +NW Sbjct: 509 TKRLGNMKNGADDVKRHRWFKHLNW 533
>CTRO_HUMAN (O14578) Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK)| (Rho-interacting, serine/threonine-protein kinase 21) Length = 2027 Score = 63.5 bits (153), Expect = 4e-10 Identities = 36/95 (37%), Positives = 52/95 (54%), Gaps = 2/95 (2%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILH--KDIRFPASISVSLPARQLIYRLLHR 411 DWW++G++ YEM+YG +PF T RTF NI++ + ++FP VS LI LL Sbjct: 285 DWWSVGVIAYEMIYGRSPFAEGTSARTFNNIMNFQRFLKFPDDPKVSSDFLDLIQSLLCG 344 Query: 410 DPANRMGSYEGSNEIKQHPFFRGINWALVRGTAPP 306 +EG + HPFF I+W +R + PP Sbjct: 345 QKERL--KFEG---LCCHPFFSKIDWNNIRNSPPP 374
>KS6A5_MOUSE (Q8C050) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1) (Nuclear| mitogen-and stress-activated protein kinase 1) (90 kDa ribosomal protein S6 kinase 5) (RSK-like protein kinase) (RLSK) Length = 863 Score = 62.8 bits (151), Expect = 7e-10 Identities = 33/87 (37%), Positives = 50/87 (57%), Gaps = 3/87 (3%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRF--PASISVSLPARQLIYRLLHR 411 DWW+LG+L+YE+L G +PF + + A I + ++ P +S A+ L+ RLL + Sbjct: 236 DWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSTVAKDLLQRLLMK 295 Query: 410 DPANRMG-SYEGSNEIKQHPFFRGINW 333 DP R+G + EIK+H FF I W Sbjct: 296 DPKKRLGCGPRDAEEIKEHLFFEKIKW 322 Score = 38.1 bits (87), Expect = 0.019 Identities = 26/73 (35%), Positives = 33/73 (45%), Gaps = 9/73 (12%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRT-------FANILHKDIRFPASI--SVSLPARQL 432 D W+LG++LY ML G PF+ R T I D F +VS A+ L Sbjct: 668 DLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNVSQEAKDL 727 Query: 431 IYRLLHRDPANRM 393 I LL DP R+ Sbjct: 728 IQGLLTVDPNKRL 740
>ARBK2_HUMAN (P35626) Beta-adrenergic receptor kinase 2 (EC 2.7.11.15)| (Beta-ARK-2) (G-protein-coupled receptor kinase 3) Length = 688 Score = 62.4 bits (150), Expect = 9e-10 Identities = 38/107 (35%), Positives = 62/107 (57%), Gaps = 9/107 (8%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFR-GKTRQRTFANILHKDIRFPASISVSLP------ARQLIY 426 DW++LG +L+++L G++PFR KT+ + H+ R +++V LP + L+ Sbjct: 373 DWFSLGCMLFKLLRGHSPFRQHKTKDK------HEIDRMTLTVNVELPDTFSPELKSLLE 426 Query: 425 RLLHRDPANRMGSY-EGSNEIKQHPFFRGINWALV-RGTAPPKLDAP 291 LL RD + R+G + GS E+K+H FF+G++W V PP L P Sbjct: 427 GLLQRDVSKRLGCHGGGSQEVKEHSFFKGVDWQHVYLQKYPPPLIPP 473
>GRK4_RAT (P70507) G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK4) Length = 575 Score = 62.4 bits (150), Expect = 9e-10 Identities = 36/112 (32%), Positives = 63/112 (56%), Gaps = 8/112 (7%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPA---SISVSLPARQLIYRLLH 414 DWW LG L+YEM+ G++PFR K +++ + + ++ S S A+ + LL Sbjct: 367 DWWGLGCLIYEMIAGHSPFR-KYKEKVNREEMERRVKTETEEYSERFSENAKSICSMLLT 425 Query: 413 RDPANRMG-SYEGSNEIKQHPFFRGINWALVRGTA--PPKLDAP--LFSKDV 273 +DP+ R+G +G++ +KQHP F+ IN++ + PP P ++ KD+ Sbjct: 426 KDPSKRLGCQSDGASAVKQHPIFKDINFSRLEANMLDPPFCPDPEAIYCKDI 477
>LATS1_HUMAN (O95835) Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large| tumor suppressor homolog 1) (WARTS protein kinase) (h-warts) Length = 1130 Score = 62.0 bits (149), Expect = 1e-09 Identities = 32/87 (36%), Positives = 52/87 (59%), Gaps = 2/87 (2%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILH--KDIRFPASISVSLPARQLIYRLLHR 411 DWW++G++L+EML G PF +T T +++ + P +S A LI +L R Sbjct: 932 DWWSVGVILFEMLVGQPPFLAQTPLETQMKVINWQTSLHIPPQAKLSPEASDLIIKLC-R 990 Query: 410 DPANRMGSYEGSNEIKQHPFFRGINWA 330 P +R+G G++EIK HPFF+ I+++ Sbjct: 991 GPEDRLGK-NGADEIKAHPFFKTIDFS 1016
>ARBK2_BOVIN (P26818) Beta-adrenergic receptor kinase 2 (EC 2.7.11.15)| (Beta-ARK-2) (G-protein-coupled receptor kinase 3) Length = 688 Score = 61.6 bits (148), Expect = 2e-09 Identities = 40/107 (37%), Positives = 61/107 (57%), Gaps = 9/107 (8%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFR-GKTRQRTFANILHKDIRFPASISVSLP------ARQLIY 426 DW++LG +L+++L G++PFR KT+ + H+ R +++V LP + L+ Sbjct: 373 DWFSLGCMLFKLLRGHSPFRQHKTKDK------HEIDRMTLTMNVELPDVFSPELKSLLE 426 Query: 425 RLLHRDPANRMGSYEGS-NEIKQHPFFRGINWALV-RGTAPPKLDAP 291 LL RD + R+G + GS E+K H FFRGI+W V PP L P Sbjct: 427 GLLQRDVSKRLGCHGGSAQELKTHDFFRGIDWQHVYLQKYPPPLIPP 473
>CTRO_MOUSE (P49025) Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK)| (Rho-interacting, serine/threonine-protein kinase 21) Length = 2055 Score = 61.6 bits (148), Expect = 2e-09 Identities = 35/95 (36%), Positives = 51/95 (53%), Gaps = 2/95 (2%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILH--KDIRFPASISVSLPARQLIYRLLHR 411 DWW++G++ YEM+YG TPF T RTF NI++ + ++FP VS L+ LL Sbjct: 284 DWWSVGVVAYEMVYGKTPFTEGTSARTFNNIMNFQRFLKFPDDPKVSSELLDLLQSLLCV 343 Query: 410 DPANRMGSYEGSNEIKQHPFFRGINWALVRGTAPP 306 +EG + HPFF +W +R + PP Sbjct: 344 QKERL--KFEG---LCCHPFFARTDWNNIRNSPPP 373
>KGP2_HUMAN (Q13237) cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2)| (cGKII) (Type II cGMP-dependent protein kinase) Length = 762 Score = 61.2 bits (147), Expect = 2e-09 Identities = 32/94 (34%), Positives = 52/94 (55%), Gaps = 1/94 (1%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 D+W+LGIL+YE+L G PF G + T+ IL + ++ LI RL ++P Sbjct: 632 DFWSLGILVYELLTGNPPFSGVDQMMTYNLILKGIEKMDFPRKITRRPEDLIRRLCRQNP 691 Query: 404 ANRMGSYE-GSNEIKQHPFFRGINWALVRGTAPP 306 R+G+ + G N+IK+H + G NW ++ + P Sbjct: 692 TERLGNLKNGINDIKKHRWLNGFNWEGLKARSLP 725
>ROCK2_RAT (Q62868) Rho-associated protein kinase 2 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 2) (p164 ROCK-2) (RhoA-binding kinase 2) (p150 ROK-alpha) (ROKalpha) Length = 1379 Score = 61.2 bits (147), Expect = 2e-09 Identities = 44/121 (36%), Positives = 61/121 (50%), Gaps = 4/121 (3%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANIL-HKD-IRFPASISVSLPARQLIYRLLHR 411 DWW++G+ L+EML G TPF + T++ I+ HK+ + FP +S A+ LI L Sbjct: 267 DWWSVGVFLFEMLVGDTPFYADSLVGTYSKIMDHKNSLCFPEDTEISKHAKNLICAFL-T 325 Query: 410 DPANRMGSYEGSNEIKQHPFFRG--INWALVRGTAPPKLDAPLFSKDVGKGMGDAAAADN 237 D R+G G EIK FF+ NW +R TA P + P S D+ D D Sbjct: 326 DREVRLGR-NGVEEIKSASFFKNDQWNWDNIRETAAPVV--PELSSDIDSSNFDDIEDDK 382 Query: 236 G 234 G Sbjct: 383 G 383
>KGP2_RAT (Q64595) cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2)| (cGKII) (Type II cGMP-dependent protein kinase) Length = 762 Score = 60.8 bits (146), Expect = 3e-09 Identities = 32/94 (34%), Positives = 52/94 (55%), Gaps = 1/94 (1%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 D+W+LGIL+YE+L G PF G + T+ IL + ++ LI RL ++P Sbjct: 632 DFWSLGILVYELLTGNPPFSGIDQMMTYNLILKGIEKMDFPRKITRRPEDLIRRLCRQNP 691 Query: 404 ANRMGSYE-GSNEIKQHPFFRGINWALVRGTAPP 306 R+G+ + G N+IK+H + G NW ++ + P Sbjct: 692 TERLGNLKNGINDIKKHRWLNGFNWEGLKARSLP 725
>KGP2_MOUSE (Q61410) cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2)| (cGKII) (Type II cGMP-dependent protein kinase) Length = 762 Score = 60.8 bits (146), Expect = 3e-09 Identities = 32/94 (34%), Positives = 52/94 (55%), Gaps = 1/94 (1%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 D+W+LGIL+YE+L G PF G + T+ IL + ++ LI RL ++P Sbjct: 632 DFWSLGILVYELLTGNPPFSGIDQMMTYNLILKGIEKMDFPRKITRRPEDLIRRLCRQNP 691 Query: 404 ANRMGSYE-GSNEIKQHPFFRGINWALVRGTAPP 306 R+G+ + G N+IK+H + G NW ++ + P Sbjct: 692 TERLGNLKNGINDIKKHRWLNGFNWEGLKARSLP 725
>COT1_NEUCR (P38679) Serine/threonine-protein kinase cot-1 (EC 2.7.11.1)| (Colonial temperature-sensitive 1) Length = 598 Score = 60.8 bits (146), Expect = 3e-09 Identities = 34/95 (35%), Positives = 54/95 (56%), Gaps = 2/95 (2%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILH--KDIRFPASISVSLPARQLIYRLLHR 411 DWW+LG +++E L G+ PF + T+ I++ + FP I++ + A LI R L Sbjct: 440 DWWSLGTIMFECLVGWPPFCAEDSHDTYRKIVNWRHSLYFPDDITLGVDAENLI-RSLIC 498 Query: 410 DPANRMGSYEGSNEIKQHPFFRGINWALVRGTAPP 306 + NR+G G++EIK H FFRG+ + +R P Sbjct: 499 NTENRLGR-GGAHEIKSHAFFRGVEFDSLRRIRAP 532
>KPC1_YEAST (P24583) Protein kinase C-like 1 (EC 2.7.11.13) (PKC 1)| Length = 1151 Score = 60.8 bits (146), Expect = 3e-09 Identities = 31/85 (36%), Positives = 48/85 (56%), Gaps = 1/85 (1%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWWA G+LLY+ML +PF G F IL + +P ++ + Q+ LL +DP Sbjct: 1006 DWWAFGVLLYQMLLCQSPFSGDDEDEVFNAILTDEPLYPIDMAGEIV--QIFQGLLTKDP 1063 Query: 404 ANRMGS-YEGSNEIKQHPFFRGINW 333 R+G+ ++E+ + PFFR IN+ Sbjct: 1064 EKRLGAGPRDADEVMEEPFFRNINF 1088
>AKT2_CAEEL (Q9XTG7) Serine/threonine-protein kinase akt-2 (EC 2.7.11.1)| (Protein kinase B akt-2) (PKB akt-2) Length = 528 Score = 60.8 bits (146), Expect = 3e-09 Identities = 33/96 (34%), Positives = 53/96 (55%), Gaps = 3/96 (3%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW +G+++YEM+ G PF K + F I D++FP +S A L+ LL R P Sbjct: 360 DWWGVGVVMYEMMCGRLPFSAKENGKLFELITTCDLKFPNRLSPE--AVTLLSGLLERVP 417 Query: 404 ANRMGS-YEGSNEIKQHPFFRGINW--ALVRGTAPP 306 A R+G+ + + E+ + FF+ ++W L + PP Sbjct: 418 AKRLGAGPDDAREVSRAEFFKDVDWEATLRKEVEPP 453
>ICL1_KLULA (Q6CWQ4) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 361 Score = 60.8 bits (146), Expect = 3e-09 Identities = 33/76 (43%), Positives = 47/76 (61%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 D WALG+L YE+L G PF T++ T+ IL D++FP ++VS AR LI RLL +P Sbjct: 279 DVWALGVLTYELLVGSPPFEEDTKEMTYRRILRCDLKFP--LNVSPQARDLIVRLLQFEP 336 Query: 404 ANRMGSYEGSNEIKQH 357 + R+ +E+K H Sbjct: 337 SKRI----PLSEVKSH 348
>GRK5_MOUSE (Q8VEB1) G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK5) Length = 590 Score = 60.8 bits (146), Expect = 3e-09 Identities = 38/113 (33%), Positives = 61/113 (53%), Gaps = 9/113 (7%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGK----TRQRTFANILHKDIRFPASISVSLPARQLIYRLL 417 D+W LG L+YEM+ G +PFRG+ R+ +L + + + S A+ + LL Sbjct: 367 DYWGLGCLIYEMIEGQSPFRGRKEKVKREEVDRRVLETEEVYSSKFSEE--AKSICNMLL 424 Query: 416 HRDPANRMG-SYEGSNEIKQHPFFRGINWALVRG--TAPPKLDAP--LFSKDV 273 +D R+G EG+ E+K+HPFFR +N+ + PP + P ++ KDV Sbjct: 425 TKDSKQRLGCQEEGAAEVKRHPFFRNMNFKRLEAGMLDPPFVPDPRAVYCKDV 477
>GRK4_MOUSE (O70291) G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK4) Length = 574 Score = 60.8 bits (146), Expect = 3e-09 Identities = 35/104 (33%), Positives = 58/104 (55%), Gaps = 6/104 (5%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPA---SISVSLPARQLIYRLLH 414 DWW LG L+YEM+ G++PFR K +++ L + ++ S S A+ + LL Sbjct: 367 DWWGLGCLIYEMIAGHSPFR-KYKEKVNREELERRVKNETEEYSERFSEDAKSICSMLLI 425 Query: 413 RDPANRMG-SYEGSNEIKQHPFFRGINWALVRGTA--PPKLDAP 291 +DP+ R+G +G + +KQHP F+ IN++ + PP + P Sbjct: 426 KDPSKRLGCQRDGVSAVKQHPIFKDINFSRLEANMLDPPFIPDP 469
>ARBK1_RAT (P26817) Beta-adrenergic receptor kinase 1 (EC 2.7.11.15)| (Beta-ARK-1) (G-protein-coupled receptor kinase 2) Length = 689 Score = 60.5 bits (145), Expect = 4e-09 Identities = 39/107 (36%), Positives = 60/107 (56%), Gaps = 9/107 (8%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFR-GKTRQRTFANILHKDIRFPASISVSLP------ARQLIY 426 DW++LG +L+++L G++PFR KT+ + H+ R +++V LP R L+ Sbjct: 373 DWFSLGCMLFKLLRGHSPFRQHKTKDK------HEIDRMTLTMAVELPDSFSPELRSLLE 426 Query: 425 RLLHRDPANRMGSY-EGSNEIKQHPFFRGINWALV-RGTAPPKLDAP 291 LL RD R+G G+ EIK+ PFFR ++W +V PP L P Sbjct: 427 GLLQRDVNRRLGCLGRGAQEIKESPFFRSLDWQMVFLQKYPPPLIPP 473
>AURKC_HUMAN (Q9UQB9) Serine/threonine-protein kinase 13 (EC 2.7.11.1)| (Aurora/Ipl1/Eg2 protein 2) (Aurora/Ipl1-related kinase 3) (Aurora-C) Length = 309 Score = 60.1 bits (144), Expect = 5e-09 Identities = 29/64 (45%), Positives = 38/64 (59%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 D W +G+L YE+L GY PF + T+ IL D+RFP +S+ L AR LI RLL P Sbjct: 221 DLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFP--LSMPLGARDLISRLLRYQP 278 Query: 404 ANRM 393 R+ Sbjct: 279 LERL 282
>GRK5_RAT (Q62833) G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK5) Length = 590 Score = 60.1 bits (144), Expect = 5e-09 Identities = 39/113 (34%), Positives = 61/113 (53%), Gaps = 9/113 (7%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGK----TRQRTFANILHKDIRFPASISVSLPARQLIYRLL 417 D+W LG L+YEM+ G +PFRG+ R+ +L + + S S A+ + LL Sbjct: 367 DYWGLGCLIYEMIEGQSPFRGRKEKVKREEVDRRVLETEEVY--SPKFSEEAKSICNMLL 424 Query: 416 HRDPANRMG-SYEGSNEIKQHPFFRGINWALVRG--TAPPKLDAP--LFSKDV 273 +D R+G EG+ E+K+HPFFR +N+ + PP + P ++ KDV Sbjct: 425 TKDSKQRLGCQEEGAAEVKRHPFFRNMNFKRLEAGMLDPPFVPDPRAVYCKDV 477
>GRK5_HUMAN (P34947) G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK5) Length = 590 Score = 60.1 bits (144), Expect = 5e-09 Identities = 39/113 (34%), Positives = 61/113 (53%), Gaps = 9/113 (7%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGK----TRQRTFANILHKDIRFPASISVSLPARQLIYRLL 417 D+W LG L+YEM+ G +PFRG+ R+ +L + + S S A+ + LL Sbjct: 367 DYWGLGCLIYEMIEGQSPFRGRKEKVKREEVDRRVLETEEVY--SHKFSEEAKSICKMLL 424 Query: 416 HRDPANRMG-SYEGSNEIKQHPFFRGINWALVRG--TAPPKLDAP--LFSKDV 273 +D R+G EG+ E+K+HPFFR +N+ + PP + P ++ KDV Sbjct: 425 TKDAKQRLGCQEEGAAEVKRHPFFRNMNFKRLEAGMLDPPFVPDPRAVYCKDV 477
>GRK5_BOVIN (P43249) G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK5) Length = 590 Score = 60.1 bits (144), Expect = 5e-09 Identities = 39/113 (34%), Positives = 61/113 (53%), Gaps = 9/113 (7%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGK----TRQRTFANILHKDIRFPASISVSLPARQLIYRLL 417 D+W LG L+YEM+ G +PFRG+ R+ +L + + S S A+ + LL Sbjct: 367 DYWGLGCLIYEMIEGQSPFRGRKEKVKREEVDRRVLETEEVY--SHKFSEEAKSICKMLL 424 Query: 416 HRDPANRMG-SYEGSNEIKQHPFFRGINWALVRG--TAPPKLDAP--LFSKDV 273 +D R+G EG+ E+K+HPFFR +N+ + PP + P ++ KDV Sbjct: 425 TKDAKQRLGCQEEGAAEVKRHPFFRNMNFKRLEAGMLDPPFVPDPRAVYCKDV 477
>ARBK1_MOUSE (Q99MK8) Beta-adrenergic receptor kinase 1 (EC 2.7.11.15)| (Beta-ARK-1) (G-protein-coupled receptor kinase 2) Length = 689 Score = 60.1 bits (144), Expect = 5e-09 Identities = 38/107 (35%), Positives = 60/107 (56%), Gaps = 9/107 (8%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFR-GKTRQRTFANILHKDIRFPASISVSLP------ARQLIY 426 DW++LG +L+++L G++PFR KT+ + H+ R +++V LP R L+ Sbjct: 373 DWFSLGCMLFKLLRGHSPFRQHKTKDK------HEIDRMTLTMAVELPDSFSPELRSLLE 426 Query: 425 RLLHRDPANRMGSY-EGSNEIKQHPFFRGINWALV-RGTAPPKLDAP 291 LL RD R+G G+ E+K+ PFFR ++W +V PP L P Sbjct: 427 GLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQKYPPPLIPP 473
>ARBK1_MESAU (Q64682) Beta-adrenergic receptor kinase 1 (EC 2.7.11.15)| (Beta-ARK-1) (G-protein-coupled receptor kinase 2) Length = 689 Score = 60.1 bits (144), Expect = 5e-09 Identities = 38/107 (35%), Positives = 60/107 (56%), Gaps = 9/107 (8%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFR-GKTRQRTFANILHKDIRFPASISVSLP------ARQLIY 426 DW++LG +L+++L G++PFR KT+ + H+ R +++V LP R L+ Sbjct: 373 DWFSLGCMLFKLLRGHSPFRQHKTKDK------HEIDRMTLTMAVELPDSFSPELRSLLE 426 Query: 425 RLLHRDPANRMGSY-EGSNEIKQHPFFRGINWALV-RGTAPPKLDAP 291 LL RD R+G G+ E+K+ PFFR ++W +V PP L P Sbjct: 427 GLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQKYPPPLIPP 473
>ARBK1_BOVIN (P21146) Beta-adrenergic receptor kinase 1 (EC 2.7.11.15)| (Beta-ARK-1) (G-protein-coupled receptor kinase 2) Length = 689 Score = 60.1 bits (144), Expect = 5e-09 Identities = 38/107 (35%), Positives = 60/107 (56%), Gaps = 9/107 (8%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFR-GKTRQRTFANILHKDIRFPASISVSLP------ARQLIY 426 DW++LG +L+++L G++PFR KT+ + H+ R +++V LP R L+ Sbjct: 373 DWFSLGCMLFKLLRGHSPFRQHKTKDK------HEIDRMTLTMAVELPDSFSPELRSLLE 426 Query: 425 RLLHRDPANRMGSY-EGSNEIKQHPFFRGINWALV-RGTAPPKLDAP 291 LL RD R+G G+ E+K+ PFFR ++W +V PP L P Sbjct: 427 GLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQKYPPPLIPP 473
>LATS1_MOUSE (Q8BYR2) Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large| tumor suppressor homolog 1) (WARTS protein kinase) Length = 1129 Score = 59.7 bits (143), Expect = 6e-09 Identities = 32/87 (36%), Positives = 50/87 (57%), Gaps = 2/87 (2%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANIL--HKDIRFPASISVSLPARQLIYRLLHR 411 DWW++G++L EML G PF +T T ++ + P +S A LI +L R Sbjct: 931 DWWSVGVILCEMLVGQPPFLAQTPLETQMKVIIWQTSLHIPPQAKLSPEASDLIIKLC-R 989 Query: 410 DPANRMGSYEGSNEIKQHPFFRGINWA 330 P +R+G G++EIK HPFF+ I+++ Sbjct: 990 GPEDRLGK-NGADEIKAHPFFKTIDFS 1015
>KGP25_DROME (P32023) cGMP-dependent protein kinase, isozyme 2 forms cD5/T2 (EC| 2.7.11.12) (CGK) (Foraging protein) Length = 934 Score = 59.7 bits (143), Expect = 6e-09 Identities = 35/88 (39%), Positives = 53/88 (60%), Gaps = 4/88 (4%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKD---IRFPASISVSLPARQLIYRLLH 414 D+W+LG+L++E+L G PF G RT+ NI+ K I FP +I+ + A LI +L Sbjct: 803 DYWSLGVLMFELLTGTPPFTGSDPMRTY-NIILKGIDAIEFPRNITRN--ASNLIKKLCR 859 Query: 413 RDPANRMGSYEGS-NEIKQHPFFRGINW 333 +PA R+G G +EI++H +F G W Sbjct: 860 DNPAERLGYQRGGISEIQKHKWFDGFYW 887
>KGP24_DROME (Q03043) cGMP-dependent protein kinase, isozyme 2 forms| cD4/T1/T3A/T3B (EC 2.7.11.12) (CGK) (Foraging protein) Length = 1088 Score = 59.7 bits (143), Expect = 6e-09 Identities = 35/88 (39%), Positives = 53/88 (60%), Gaps = 4/88 (4%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKD---IRFPASISVSLPARQLIYRLLH 414 D+W+LG+L++E+L G PF G RT+ NI+ K I FP +I+ + A LI +L Sbjct: 957 DYWSLGVLMFELLTGTPPFTGSDPMRTY-NIILKGIDAIEFPRNITRN--ASNLIKKLCR 1013 Query: 413 RDPANRMGSYEGS-NEIKQHPFFRGINW 333 +PA R+G G +EI++H +F G W Sbjct: 1014 DNPAERLGYQRGGISEIQKHKWFDGFYW 1041
>IPL1_ASHGO (Q755C4) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 367 Score = 59.3 bits (142), Expect = 8e-09 Identities = 31/78 (39%), Positives = 47/78 (60%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 D WALG+L YE+L G PF ++++ T+ IL +++ FP + AR LI RLL DP Sbjct: 288 DVWALGVLTYELLVGSPPFEEESKELTYKRILKRNLIFPDHVDTE--ARHLISRLLEYDP 345 Query: 404 ANRMGSYEGSNEIKQHPF 351 +R+ E+K+HP+ Sbjct: 346 GDRI----PLKEVKKHPW 359
>GPRK1_DROME (P32865) G protein-coupled receptor kinase 1 (EC 2.7.11.16)| Length = 700 Score = 59.3 bits (142), Expect = 8e-09 Identities = 31/86 (36%), Positives = 51/86 (59%), Gaps = 2/86 (2%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFR-GKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRD 408 DW++ G +LY++L G++PFR KT+ + + + + S SL + L+ LL RD Sbjct: 374 DWFSFGCMLYKLLKGHSPFRQHKTKDKLEIDKMTLTMNVELPESFSLELKNLLEMLLQRD 433 Query: 407 PANRMGSY-EGSNEIKQHPFFRGINW 333 + R+G G++E+K H FF GI+W Sbjct: 434 VSKRLGCMGNGADEVKMHNFFCGIDW 459
>DBF20_YEAST (P32328) Serine/threonine-protein kinase DBF20 (EC 2.7.11.1)| Length = 564 Score = 58.9 bits (141), Expect = 1e-08 Identities = 35/99 (35%), Positives = 58/99 (58%), Gaps = 6/99 (6%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILH--KDIRFPAS----ISVSLPARQLIYR 423 D+W+LG +L+E L GYTPF G + T+ N+ + K +R P + + S LI R Sbjct: 389 DYWSLGCMLFESLVGYTPFSGSSTNETYENLRYWKKTLRRPRTEDRRAAFSDRTWDLITR 448 Query: 422 LLHRDPANRMGSYEGSNEIKQHPFFRGINWALVRGTAPP 306 L+ DP NR+ S+E ++++ +F IN+ +R ++PP Sbjct: 449 LI-ADPINRVRSFE---QVRKMSYFAEINFETLRTSSPP 483
>LATS2_HUMAN (Q9NRM7) Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Large| tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Kinase phosphorylated during mitosis protein) (Warts-like kinase) Length = 1088 Score = 58.2 bits (139), Expect = 2e-08 Identities = 30/87 (34%), Positives = 51/87 (58%), Gaps = 2/87 (2%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILH--KDIRFPASISVSLPARQLIYRLLHR 411 DWW++G++L+EML G PF T T +++ + PA + +S AR LI +L Sbjct: 895 DWWSVGVILFEMLVGQPPFLAPTPTETQLKVINWENTLHIPAQVKLSPEARDLITKLC-C 953 Query: 410 DPANRMGSYEGSNEIKQHPFFRGINWA 330 +R+G G++++K HPFF I+++ Sbjct: 954 SADHRLGR-NGADDLKAHPFFSAIDFS 979
>KSG1_SCHPO (Q12701) Serine/threonine-protein kinase ksg1 (EC 2.7.11.1)| Length = 592 Score = 58.2 bits (139), Expect = 2e-08 Identities = 37/93 (39%), Positives = 46/93 (49%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 D WA G +L++ML G PF TF +ILH P IS A LI +LL DP Sbjct: 294 DIWAFGCILFQMLAGKPPFVAGNEYLTFQSILHLSYEIPPDISD--VASDLIKKLLVLDP 351 Query: 404 ANRMGSYEGSNEIKQHPFFRGINWALVRGTAPP 306 +R+ +EI QHPFF GI + PP Sbjct: 352 KDRL----TVDEIHQHPFFNGIKFDNTLWELPP 380
>ARBK1_HUMAN (P25098) Beta-adrenergic receptor kinase 1 (EC 2.7.11.15)| (Beta-ARK-1) (G-protein coupled receptor kinase 2) Length = 689 Score = 58.2 bits (139), Expect = 2e-08 Identities = 37/107 (34%), Positives = 59/107 (55%), Gaps = 9/107 (8%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFR-GKTRQRTFANILHKDIRFPASISVSLP------ARQLIY 426 DW++LG +L+++L G++PFR KT+ + H+ R +++V LP L+ Sbjct: 373 DWFSLGCMLFKLLRGHSPFRQHKTKDK------HEIDRMTLTMAVELPDSFSPELHSLLE 426 Query: 425 RLLHRDPANRMGSY-EGSNEIKQHPFFRGINWALV-RGTAPPKLDAP 291 LL RD R+G G+ E+K+ PFFR ++W +V PP L P Sbjct: 427 GLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQRYPPPLIPP 473
>DBF2_YEAST (P22204) Cell cycle protein kinase DBF2 (EC 2.7.11.1)| Length = 572 Score = 57.8 bits (138), Expect = 2e-08 Identities = 34/99 (34%), Positives = 53/99 (53%), Gaps = 6/99 (6%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANI------LHKDIRFPASISVSLPARQLIYR 423 D+W+LG +L+E L GYTPF G + T+ N+ L + + + S LI R Sbjct: 397 DYWSLGCMLFESLVGYTPFSGSSTNETYDNLRRWKQTLRRPRQSDGRAAFSDRTWDLITR 456 Query: 422 LLHRDPANRMGSYEGSNEIKQHPFFRGINWALVRGTAPP 306 L+ DP NR+ S+E +K+ +F IN++ +R PP Sbjct: 457 LI-ADPINRLRSFE---HVKRMSYFADINFSTLRSMIPP 491
>CDPK1_ARATH (Q06850) Calcium-dependent protein kinase, isoform AK1 (EC| 2.7.11.1) (CDPK) Length = 610 Score = 57.8 bits (138), Expect = 2e-08 Identities = 35/105 (33%), Positives = 57/105 (54%), Gaps = 3/105 (2%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPAS--ISVSLPARQLIYRLLHR 411 D W+ G+++Y +L G PF +T Q F +LH D+ F + S+S A+ L+ ++L R Sbjct: 332 DVWSAGVIVYILLSGVPPFWAETEQGIFEQVLHGDLDFSSDPWPSISESAKDLVRKMLVR 391 Query: 410 DPANRMGSYEGSNEIKQHPFFRGINWALVRGTAPPK-LDAPLFSK 279 DP R+ ++ ++ HP W V G AP K LD+ + S+ Sbjct: 392 DPKKRLTAH----QVLCHP------WVQVDGVAPDKPLDSAVLSR 426
>PSK1_SCHPO (Q12706) Serine/threonine-protein kinase psk1 (EC 2.7.11.22)| Length = 436 Score = 57.4 bits (137), Expect = 3e-08 Identities = 31/99 (31%), Positives = 52/99 (52%), Gaps = 4/99 (4%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 DWW++GIL++++L G PF +R I P V+ AR +I + L ++P Sbjct: 271 DWWSMGILIFDLLTGSPPFTANNHKRIMEKITRAKPNIP--FYVTSDARDIINKFLKKNP 328 Query: 404 ANRMGS---YEGSNEIKQHPFFRGINW-ALVRGTAPPKL 300 R+G+ +G + IK+H +R I+W L + PP + Sbjct: 329 KQRLGADGPEKGYDAIKKHRIYRRIDWNKLEKRMLPPPI 367
>PDPK1_CAEEL (Q9Y1J3) 3-phophoinositide-dependent protein kinase 1 (EC 2.7.11.1)| (Pdk-class protein kinase protein 1) Length = 636 Score = 56.6 bits (135), Expect = 5e-08 Identities = 31/97 (31%), Positives = 45/97 (46%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILHKDIRFPASISVSLPARQLIYRLLHRDP 405 D W LG +L++ L G PFR + I D FP A ++I ++L RDP Sbjct: 292 DIWGLGCILFQCLAGQPPFRAVNQYHLLKRIQELDFSFPEGFPEE--ASEIIAKILVRDP 349 Query: 404 ANRMGSYEGSNEIKQHPFFRGINWALVRGTAPPKLDA 294 + R+ S E+ H FF ++W + PP L A Sbjct: 350 STRI----TSQELMAHKFFENVDWVNIANIKPPVLHA 382
>LATS2_MOUSE (Q7TSJ6) Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Large| tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Kinase phosphorylated during mitosis protein) Length = 1042 Score = 56.6 bits (135), Expect = 5e-08 Identities = 29/87 (33%), Positives = 50/87 (57%), Gaps = 2/87 (2%) Frame = -3 Query: 584 DWWALGILLYEMLYGYTPFRGKTRQRTFANILH--KDIRFPASISVSLPARQLIYRLLHR 411 DWW++G++L+EML G PF T T +++ + P + +S AR LI +L Sbjct: 853 DWWSVGVILFEMLVGQPPFLAPTPTETQLKVINWESTLHIPTQVRLSAEARDLITKLCCA 912 Query: 410 DPANRMGSYEGSNEIKQHPFFRGINWA 330 R+G +G++++K HPFF I+++ Sbjct: 913 ADC-RLGR-DGADDLKAHPFFNTIDFS 937 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 90,419,775 Number of Sequences: 219361 Number of extensions: 2005256 Number of successful extensions: 7932 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 6763 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 7502 length of database: 80,573,946 effective HSP length: 106 effective length of database: 57,321,680 effective search space used: 5044307840 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
