>MTHR_ORYSA (Q75HE6) Probable methylenetetrahydrofolate reductase (EC 1.5.1.20)|
          Length = 594

 Score =  221 bits (562), Expect = 9e-58
 Identities = 105/116 (90%), Positives = 113/116 (97%)
 Frame = -3

Query: 466 LDQLIEKSKAFPSLTYIAVNKEGESISNIPANAVNAVTWGVFPGKEIIQPTVVDSASFMV 287
           LDQLIEKSKAFPSLTYIAVNK+GES SNIP NAVNAVTWGVFPGKEI+QPTVVDSASFMV
Sbjct: 479 LDQLIEKSKAFPSLTYIAVNKDGESFSNIPTNAVNAVTWGVFPGKEIVQPTVVDSASFMV 538

Query: 286 WKDEAFEIWSRGWACLFPEGDSSRELLEQVQKTYCLVSLVDNDYISGDLFAAFKEI 119
           WKDEAFEIWS+GWACLFPEGDSSRE+L++VQK+Y LVSLVDNDYI+GDLFAAFKEI
Sbjct: 539 WKDEAFEIWSKGWACLFPEGDSSREILDKVQKSYFLVSLVDNDYINGDLFAAFKEI 594

>MTHR1_MAIZE (Q9SE94) Methylenetetrahydrofolate reductase 1 (EC 1.5.1.20)|
           (ZmMTHFR1)
          Length = 593

 Score =  209 bits (532), Expect = 3e-54
 Identities = 100/114 (87%), Positives = 106/114 (92%)
 Frame = -3

Query: 466 LDQLIEKSKAFPSLTYIAVNKEGESISNIPANAVNAVTWGVFPGKEIIQPTVVDSASFMV 287
           LDQLIEK KAFPSLTYIAVNK+GE+ SNI  NAVNAVTWGVFPGKEIIQPTVVD ASFMV
Sbjct: 479 LDQLIEKIKAFPSLTYIAVNKDGETFSNISPNAVNAVTWGVFPGKEIIQPTVVDHASFMV 538

Query: 286 WKDEAFEIWSRGWACLFPEGDSSRELLEQVQKTYCLVSLVDNDYISGDLFAAFK 125
           WKDEAFEIW+RGW C+FPEGDSSRELLE+VQKTY LVSLVDNDY+ GDLFAAFK
Sbjct: 539 WKDEAFEIWTRGWGCMFPEGDSSRELLEKVQKTYYLVSLVDNDYVQGDLFAAFK 592

>MTHR1_ARATH (Q9SE60) Methylenetetrahydrofolate reductase 1 (EC 1.5.1.20)|
           (AtMTHFR1)
          Length = 592

 Score =  167 bits (422), Expect = 2e-41
 Identities = 78/113 (69%), Positives = 94/113 (83%)
 Frame = -3

Query: 466 LDQLIEKSKAFPSLTYIAVNKEGESISNIPANAVNAVTWGVFPGKEIIQPTVVDSASFMV 287
           LD L+EKSKAFPS+TY+AVNK    +SN   + VNAVTWGVFP KE+IQPT+VD ASF V
Sbjct: 479 LDTLVEKSKAFPSITYMAVNKSENWVSNTGESDVNAVTWGVFPAKEVIQPTIVDPASFKV 538

Query: 286 WKDEAFEIWSRGWACLFPEGDSSRELLEQVQKTYCLVSLVDNDYISGDLFAAF 128
           WKDEAFEIWSR WA L+PE D SR+LLE+V+ +Y LVSLVDN+YI+GD+F+ F
Sbjct: 539 WKDEAFEIWSRSWANLYPEDDPSRKLLEEVKNSYYLVSLVDNNYINGDIFSVF 591

>MTHR2_ARATH (O80585) Methylenetetrahydrofolate reductase 2 (EC 1.5.1.20)|
           (AtMTHFR2)
          Length = 594

 Score =  161 bits (408), Expect = 7e-40
 Identities = 76/116 (65%), Positives = 92/116 (79%)
 Frame = -3

Query: 466 LDQLIEKSKAFPSLTYIAVNKEGESISNIPANAVNAVTWGVFPGKEIIQPTVVDSASFMV 287
           LD ++EK KA PS+TY+AVNK  + +SN     VNAVTWGVFP KEIIQPT+VD ASF V
Sbjct: 479 LDAVVEKCKALPSITYMAVNKGEQWVSNTAQADVNAVTWGVFPAKEIIQPTIVDPASFNV 538

Query: 286 WKDEAFEIWSRGWACLFPEGDSSRELLEQVQKTYCLVSLVDNDYISGDLFAAFKEI 119
           WKDEAFE WSR WA L+PE D SR LLE+V+ +Y LVSLV+NDYI+GD+FA F ++
Sbjct: 539 WKDEAFETWSRSWANLYPEADPSRNLLEEVKNSYYLVSLVENDYINGDIFAVFADL 594

>MTHR_HUMAN (P42898) Methylenetetrahydrofolate reductase (EC 1.5.1.20)|
          Length = 656

 Score =  108 bits (271), Expect = 5e-24
 Identities = 49/91 (53%), Positives = 63/91 (69%)
 Frame = -3

Query: 427 LTYIAVNKEGESISNIPANAVNAVTWGVFPGKEIIQPTVVDSASFMVWKDEAFEIWSRGW 248
           + Y  VN +GE+I+N P    NAVTWG+FPG+EIIQPTVVD  SFM WKDEAF +W   W
Sbjct: 536 VNYHLVNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIERW 595

Query: 247 ACLFPEGDSSRELLEQVQKTYCLVSLVDNDY 155
             L+ E   SR +++ +   Y LV+LVDND+
Sbjct: 596 GKLYEEESPSRTIIQYIHDNYFLVNLVDNDF 626

>MTHR_MACFA (Q60HE5) Methylenetetrahydrofolate reductase (EC 1.5.1.20)|
          Length = 656

 Score =  108 bits (270), Expect = 7e-24
 Identities = 49/91 (53%), Positives = 63/91 (69%)
 Frame = -3

Query: 427 LTYIAVNKEGESISNIPANAVNAVTWGVFPGKEIIQPTVVDSASFMVWKDEAFEIWSRGW 248
           + Y  VN +GE+I+N P    NAVTWG+FPG+EIIQPTVVD  SFM WKDEAF +W   W
Sbjct: 536 VNYHLVNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQW 595

Query: 247 ACLFPEGDSSRELLEQVQKTYCLVSLVDNDY 155
             L+ E   SR +++ +   Y LV+LVDND+
Sbjct: 596 GKLYEEESPSRTIIQYIHDNYFLVNLVDNDF 626

>MTHR_MOUSE (Q9WU20) Methylenetetrahydrofolate reductase (EC 1.5.1.20)|
          Length = 654

 Score =  104 bits (260), Expect = 1e-22
 Identities = 47/91 (51%), Positives = 63/91 (69%)
 Frame = -3

Query: 427 LTYIAVNKEGESISNIPANAVNAVTWGVFPGKEIIQPTVVDSASFMVWKDEAFEIWSRGW 248
           + Y  V+ +GE+I+N P    NAVTWG+FPG+EIIQPTVVD  SFM WKDEAF +W   W
Sbjct: 535 VNYHIVDVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQW 594

Query: 247 ACLFPEGDSSRELLEQVQKTYCLVSLVDNDY 155
             L+ E   SR +++ +   Y LV+LVDN++
Sbjct: 595 GKLYEEESPSRMIIQYIHDNYFLVNLVDNEF 625

>MTHR2_YEAST (P53128) Methylenetetrahydrofolate reductase 2 (EC 1.5.1.20)|
          Length = 599

 Score = 96.3 bits (238), Expect = 3e-20
 Identities = 49/111 (44%), Positives = 73/111 (65%), Gaps = 3/111 (2%)
 Frame = -3

Query: 466 LDQLIEKSKAFPSLTYIAVNKEGESISNIPANAV-NAVTWGVFPGKEIIQPTVVDSASFM 290
           L +LI+  K    LTY A++ +G+ +SN P N+  NAVTWG+FPG+EI+QPT+V+  SF+
Sbjct: 480 LPKLIDTLKNNEFLTYFAIDSQGDLLSNHPDNSKSNAVTWGIFPGREILQPTIVEKISFL 539

Query: 289 VWKDEAFEIWSRGWACLFPEGDS--SRELLEQVQKTYCLVSLVDNDYISGD 143
            WK+E + I +  W     + D   S + ++ +   YCLV++VDNDYIS D
Sbjct: 540 AWKEEFYHILNE-WKLNMNKYDKPHSAQFIQSLIDDYCLVNIVDNDYISPD 589

>MTHR1_SCHPO (Q10258) Methylenetetrahydrofolate reductase 1 (EC 1.5.1.20)|
          Length = 603

 Score = 95.1 bits (235), Expect = 8e-20
 Identities = 50/117 (42%), Positives = 71/117 (60%), Gaps = 1/117 (0%)
 Frame = -3

Query: 466 LDQLIEKSKAFPSLTYIAVNKEGESISNIPANAVNAVTWGVFPGKEIIQPTVVDSASFMV 287
           L++L E  K   S++Y   NK G+  +N      NAVTWGVFP +EIIQPT+V+S SF+ 
Sbjct: 472 LNELKETVKKLNSVSYFVTNKNGDLDTNSQYEIPNAVTWGVFPNREIIQPTIVESTSFLA 531

Query: 286 WKDEAFEIWSRGWACLFPEGDSSRELLEQVQKTYCLVSLVDNDYISG-DLFAAFKEI 119
           WKDEA+ +    WA  +     SR+LL  + K + L  +VDND+ +G  LF  F ++
Sbjct: 532 WKDEAYSL-GMEWANAYSPDSISRKLLVSMMKEWFLCVIVDNDFQNGQSLFDVFNKM 587

>MTHR2_SCHPO (O74927) Methylenetetrahydrofolate reductase 2 (EC 1.5.1.20)|
          Length = 641

 Score = 87.0 bits (214), Expect = 2e-17
 Identities = 41/105 (39%), Positives = 63/105 (60%)
 Frame = -3

Query: 466 LDQLIEKSKAFPSLTYIAVNKEGESISNIPANAVNAVTWGVFPGKEIIQPTVVDSASFMV 287
           L   I K    P +TY A N + E ++N P +  +AVTWGV+PG+EIIQ T++   SF  
Sbjct: 525 LKDFITKWHDNPQVTYYAGNNKSEFLTNAPKDGASAVTWGVYPGREIIQSTIIAEVSFKA 584

Query: 286 WKDEAFEIWSRGWACLFPEGDSSRELLEQVQKTYCLVSLVDNDYI 152
           W  E+F++W   WA L+ +   SR+LLE       LV+++ +D++
Sbjct: 585 WLSESFQVWGE-WANLYSKNTPSRKLLENCINDRWLVTVIHHDFM 628

>MTHR_CAEEL (Q17693) Probable methylenetetrahydrofolate reductase (EC 1.5.1.20)|
          Length = 663

 Score = 86.7 bits (213), Expect = 3e-17
 Identities = 46/106 (43%), Positives = 64/106 (60%), Gaps = 2/106 (1%)
 Frame = -3

Query: 466 LDQLIEKSKAFP-SLTYIAVNKEGE-SISNIPANAVNAVTWGVFPGKEIIQPTVVDSASF 293
           L Q+IE+   FP  + Y A+NK+     +N       AVTWGVFPG EI QPTVVD  SF
Sbjct: 541 LIQIIERE--FPVRVNYHAINKDSTFDKTNSEETTPIAVTWGVFPGSEIAQPTVVDPLSF 598

Query: 292 MVWKDEAFEIWSRGWACLFPEGDSSRELLEQVQKTYCLVSLVDNDY 155
             W+DEA+++W   W   +P+   S  +++ V   + LV+LVDND+
Sbjct: 599 RAWRDEAYQMWMAQWGDFYPKESKSYGVIKAVHDEFRLVTLVDNDF 644

>MTHR1_YEAST (P46151) Methylenetetrahydrofolate reductase 1 (EC 1.5.1.20)|
          Length = 657

 Score = 85.1 bits (209), Expect = 8e-17
 Identities = 40/94 (42%), Positives = 56/94 (59%)
 Frame = -3

Query: 424 TYIAVNKEGESISNIPANAVNAVTWGVFPGKEIIQPTVVDSASFMVWKDEAFEIWSRGWA 245
           +Y A +  G   +N+  ++ + VTWGVFP   + Q T+++  SF  W+DEAF IWS  WA
Sbjct: 555 SYYAGDSSGSFETNLDPHSSSVVTWGVFPNSPVKQTTIIEEESFKAWRDEAFSIWSE-WA 613

Query: 244 CLFPEGDSSRELLEQVQKTYCLVSLVDNDYISGD 143
            LFP    +  LL  V K YCLVS+V +D+   D
Sbjct: 614 KLFPRNTPANILLRLVHKDYCLVSIVHHDFKETD 647

>PROS_RABIT (P98118) Vitamin K-dependent protein S precursor (Fragment)|
          Length = 646

 Score = 32.3 bits (72), Expect = 0.62
 Identities = 14/43 (32%), Positives = 22/43 (51%)
 Frame = -3

Query: 256 RGWACLFPEGDSSRELLEQVQKTYCLVSLVDNDYISGDLFAAF 128
           RGW  +       +E+++Q QK +CLV++    Y  G   A F
Sbjct: 422 RGWNLMKQGASGVKEIIQQKQKKHCLVTVEKGSYYPGSGIAQF 464

>YB1C_SCHPO (P87177) Hypothetical WD-repeat protein C3D6.12 in chromosome II|
          Length = 922

 Score = 30.8 bits (68), Expect = 1.8
 Identities = 21/62 (33%), Positives = 31/62 (50%)
 Frame = -3

Query: 325 IQPTVVDSASFMVWKDEAFEIWSRGWACLFPEGDSSRELLEQVQKTYCLVSLVDNDYISG 146
           + PT V S S     D +  +W +G   +F E +  REL EQ + T  LVS  +N    G
Sbjct: 668 VGPTFVVSGSH----DHSIRLWEQGDDLVFLEEERERELEEQYEST--LVSSYENAEADG 721

Query: 145 DL 140
           ++
Sbjct: 722 EV 723

>BUN2_DROME (Q24523) Protein bunched, class 2 isoform (Protein shortsighted)|
          Length = 1206

 Score = 30.4 bits (67), Expect = 2.3
 Identities = 22/63 (34%), Positives = 32/63 (50%), Gaps = 9/63 (14%)
 Frame = -3

Query: 400 GESISNIPANA----VNAVTWGVFPG----KEIIQPTVVDSASFMVWKDEAFEIWSRG-W 248
           G++I N+  N     +N V+  V PG    K+ I+ T   S  F V K E+ E + RG W
Sbjct: 466 GQTIQNVQVNVSDNIINVVSGAVTPGGTKKKDDIKETQHRSERFKVVKIESTEPFKRGRW 525

Query: 247 ACL 239
            C+
Sbjct: 526 MCM 528

>DXR_LEIXX (Q6AEY1) 1-deoxy-D-xylulose 5-phosphate reductoisomerase (EC|
           1.1.1.267) (DXP reductoisomerase)
           (1-deoxyxylulose-5-phosphate reductoisomerase)
           (2-C-methyl-D-erythritol 4-phosphate synthase)
          Length = 361

 Score = 30.0 bits (66), Expect = 3.1
 Identities = 11/24 (45%), Positives = 14/24 (58%)
 Frame = +1

Query: 202 ALATPWMSHPPGTGRPIPWTRSQT 273
           +L   W    PGTG P+ WTR+ T
Sbjct: 247 SLGLGWPDRVPGTGLPLDWTRAHT 270

>XYLA_STRLI (Q9RFM4) Xylose isomerase (EC 5.3.1.5)|
          Length = 395

 Score = 29.3 bits (64), Expect = 5.2
 Identities = 13/34 (38%), Positives = 19/34 (55%)
 Frame = -3

Query: 271 FEIWSRGWACLFPEGDSSRELLEQVQKTYCLVSL 170
           F +W+ GW  L P GD++RE L+  +    L  L
Sbjct: 13  FGLWTVGWQGLDPFGDATREALDPAESVRRLSQL 46

>KLK10_RAT (P36375) Glandular kallikrein-10 precursor (EC 3.4.21.35) (Tissue|
           kallikrein) (T-kininogenase) (K10) (Proteinase B)
           (Endopeptidase K) [Contains: T-kininogenase light chain;
           T-kininogenase heavy chain] (Fragment)
          Length = 244

 Score = 29.3 bits (64), Expect = 5.2
 Identities = 15/41 (36%), Positives = 21/41 (51%)
 Frame = +2

Query: 254 PGPDLKRFIFPNHEARRVNDGRLDDLLAGEHAPSDSVHGVR 376
           P PD K F+  NH  +R +D   D +L     P+D   GV+
Sbjct: 80  PHPDYKPFLMRNHTRQRGDDYSNDLMLLHLSEPADITDGVK 120

>XYLA_ARTS7 (P12070) Xylose isomerase (EC 5.3.1.5)|
          Length = 394

 Score = 28.9 bits (63), Expect = 6.8
 Identities = 21/75 (28%), Positives = 34/75 (45%), Gaps = 7/75 (9%)
 Frame = -3

Query: 325 IQPTVVDSASFMVWKDEAFEIWSRGWACLFPEGDSSRELLEQVQKTYCL-------VSLV 167
           +QPT  D  +F         +W+ GW    P G ++R+ L+ V+  + L       ++  
Sbjct: 2   VQPTPADHFTF--------GLWTVGWTGADPFGVATRKNLDPVEAVHKLAELGAYGITFH 53

Query: 166 DNDYISGDLFAAFKE 122
           DND I  D   A +E
Sbjct: 54  DNDLIPFDATEAERE 68

>MDHM_YEAST (P17505) Malate dehydrogenase, mitochondrial precursor (EC|
           1.1.1.37)
          Length = 334

 Score = 28.9 bits (63), Expect = 6.8
 Identities = 23/75 (30%), Positives = 36/75 (48%), Gaps = 7/75 (9%)
 Frame = -3

Query: 394 SISNIPANAVNAVTWGVFPGKEIIQPTVVDSASFMVWKDEAFEIWSR-------GWACLF 236
           S+++  A   NAV  G    +++I+P+ VDS  F   K E  E ++        G   + 
Sbjct: 244 SMAHAGAKFANAVLSGFKGERDVIEPSFVDSPLF---KSEGIEFFASPVTLGPDGIEKIH 300

Query: 235 PEGDSSRELLEQVQK 191
           P G+ S E  E +QK
Sbjct: 301 PIGELSSEEEEMLQK 315

>TNF10_HUMAN (P50591) Tumor necrosis factor ligand superfamily member 10|
           (TNF-related apoptosis-inducing ligand) (TRAIL protein)
           (Apo-2 ligand) (Apo-2L) (CD253 antigen)
          Length = 281

 Score = 28.9 bits (63), Expect = 6.8
 Identities = 25/86 (29%), Positives = 41/86 (47%), Gaps = 2/86 (2%)
 Frame = +1

Query: 28  VVWINRHKSRQIVLQDSNEGRSNT*DIIEIRSP*MQQRGP-R*CSHCPQG*PGNRSSAPA 204
           V W  R   R+++L+ S E  S   +  +  SP +++RGP R  +H      G R  +  
Sbjct: 80  VKWQLRQLVRKMILRTSEETISTVQEKQQNISPLVRERGPQRVAAHI----TGTRGRSNT 135

Query: 205 LATPWMSHPPGTGRPI-PWTRSQTLH 279
           L++P   +    GR I  W  S++ H
Sbjct: 136 LSSPNSKNEKALGRKINSWESSRSGH 161

>PEP1A_STRCO (Q9L1K2) Putative glucanohydrolase pep1A (EC 3.2.1.-)|
          Length = 675

 Score = 28.5 bits (62), Expect = 8.9
 Identities = 18/68 (26%), Positives = 30/68 (44%), Gaps = 7/68 (10%)
 Frame = -3

Query: 379 PANAVNAV-------TWGVFPGKEIIQPTVVDSASFMVWKDEAFEIWSRGWACLFPEGDS 221
           PA  V AV       TWG++ G E+ + T +   S      E +++  R W     EG +
Sbjct: 492 PAFEVRAVLAATLSPTWGIYSGYELCENTPLREGSEEYLDSEKYQLKPRDWTRAAREGTT 551

Query: 220 SRELLEQV 197
              L+ ++
Sbjct: 552 IAPLVTRL 559

>PEP1B_STRCO (Q9KY04) Putative glucanohydrolase pep1B (EC 3.2.1.-)|
          Length = 669

 Score = 28.5 bits (62), Expect = 8.9
 Identities = 18/68 (26%), Positives = 30/68 (44%), Gaps = 7/68 (10%)
 Frame = -3

Query: 379 PANAVNAV-------TWGVFPGKEIIQPTVVDSASFMVWKDEAFEIWSRGWACLFPEGDS 221
           PA  V AV       TWG++ G E+ + T +   S      E +++  R W     EG +
Sbjct: 483 PAFEVRAVLAATLSPTWGIYSGYELCENTPLREGSEEYLDSEKYQLKPRDWTRAAREGTT 542

Query: 220 SRELLEQV 197
              L+ ++
Sbjct: 543 IAPLVTRL 550


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 70,876,246
Number of Sequences: 219361
Number of extensions: 1544446
Number of successful extensions: 4204
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 4044
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4198
length of database: 80,573,946
effective HSP length: 103
effective length of database: 57,979,763
effective search space used: 3014947676
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)