ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | rbags4g06 |
|---|---|
| Clone Library Name | barley_pub |
>HT1_ARATH (Q2MHE4) Serine/threonine-protein kinase HT1 (EC 2.7.11.1) (High| leaf temperature protein 1) Length = 390 Score = 86.7 bits (213), Expect = 5e-17 Identities = 36/78 (46%), Positives = 55/78 (70%) Frame = -2 Query: 637 DVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 458 DV+SFGI+LWEL T +P++ +TP+QAA V +K RP +P + L L+++CW ++P Sbjct: 268 DVYSFGIVLWELTTALLPFQGMTPVQAAFAVAEKNERPPLPASCQPALAHLIKRCWSENP 327 Query: 457 AERPDFSEILEALKKIAE 404 ++RPDFS I+ L+K E Sbjct: 328 SKRPDFSNIVAVLEKYDE 345
>M3KSL_DROME (Q95UN8) Mitogen-activated protein kinase kinase kinase (EC| 2.7.11.25) (Mixed lineage kinase) (dMLK) (Protein slipper) Length = 1161 Score = 78.6 bits (192), Expect = 1e-14 Identities = 37/78 (47%), Positives = 49/78 (62%) Frame = -2 Query: 640 ADVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQD 461 +DV+S+G+LLWEL+TG+ PY+ PL A GV L IPK L++ CWQ D Sbjct: 326 SDVWSYGVLLWELITGETPYKGFDPLSVAYGVAVNTLTLPIPKTCPETWGALMKSCWQTD 385 Query: 460 PAERPDFSEILEALKKIA 407 P +RP F EIL+ L+ IA Sbjct: 386 PHKRPGFKEILKQLESIA 403
>M3K11_HUMAN (Q16584) Mitogen-activated protein kinase kinase kinase 11 (EC| 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline-rich kinase) Length = 847 Score = 77.8 bits (190), Expect = 3e-14 Identities = 36/81 (44%), Positives = 49/81 (60%) Frame = -2 Query: 640 ADVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQD 461 +DV+SFG+LLWELLTG++PY + L A GV L IP +L+ CW QD Sbjct: 303 SDVWSFGVLLWELLTGEVPYRGIDCLAVAYGVAVNKLTLPIPSTCPEPFAQLMADCWAQD 362 Query: 460 PAERPDFSEILEALKKIAEEV 398 P RPDF+ IL+ L+ + +V Sbjct: 363 PHRRPDFASILQQLEALEAQV 383
>M3K10_HUMAN (Q02779) Mitogen-activated protein kinase kinase kinase 10 (EC| 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST) Length = 954 Score = 77.4 bits (189), Expect = 3e-14 Identities = 36/79 (45%), Positives = 47/79 (59%) Frame = -2 Query: 640 ADVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQD 461 +DV+SFG+LLWELLTG++PY + L A GV L IP LL++CW D Sbjct: 284 SDVWSFGVLLWELLTGEVPYREIDALAVAYGVAMNKLTLPIPSTCPEPFARLLEECWDPD 343 Query: 460 PAERPDFSEILEALKKIAE 404 P RPDF IL+ L+ I + Sbjct: 344 PHGRPDFGSILKRLEVIEQ 362
>M3KL4_HUMAN (Q5TCX8) Mitogen-activated protein kinase kinase kinase (EC| 2.7.11.25) (Mixed lineage kinase 4) Length = 1036 Score = 75.5 bits (184), Expect = 1e-13 Identities = 37/84 (44%), Positives = 50/84 (59%) Frame = -2 Query: 640 ADVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQD 461 +D++S+G+LLWELLTG++PY + L A GV L IP +L+++CWQQD Sbjct: 325 SDIWSYGVLLWELLTGEVPYRGIDGLAVAYGVAVNKLTLPIPSTCPEPFAKLMKECWQQD 384 Query: 460 PAERPDFSEILEALKKIAEEVGDE 389 P RP F+ ILE L I V E Sbjct: 385 PHIRPSFALILEQLTAIEGAVMTE 408
>KYK2_DICDI (P18161) Tyrosine-protein kinase 2 (EC 2.7.10.2) (Fragment)| Length = 410 Score = 73.2 bits (178), Expect = 6e-13 Identities = 33/77 (42%), Positives = 50/77 (64%) Frame = -2 Query: 637 DVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 458 DV+ F +++WE+LTG+IP+ L Q + V GLRP IP+ +L LL +CW+ DP Sbjct: 292 DVYCFSLVVWEILTGEIPFSDLDGSQRSAQVAYAGLRPPIPEYCDPELKLLLTQCWEADP 351 Query: 457 AERPDFSEILEALKKIA 407 +RP F+ I+ LK+I+ Sbjct: 352 NDRPPFTYIVNKLKEIS 368
>M3K9_HUMAN (P80192) Mitogen-activated protein kinase kinase kinase 9 (EC| 2.7.11.25) (Mixed lineage kinase 1) Length = 1104 Score = 72.8 bits (177), Expect = 8e-13 Identities = 33/79 (41%), Positives = 46/79 (58%) Frame = -2 Query: 640 ADVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQD 461 +DV+S+G+LLWELLTG++P+ + L A GV L IP +L++ CW D Sbjct: 330 SDVWSYGVLLWELLTGEVPFRGIDGLAVAYGVAMNKLALPIPSTCPEPFAKLMEDCWNPD 389 Query: 460 PAERPDFSEILEALKKIAE 404 P RP F+ IL+ L I E Sbjct: 390 PHSRPSFTNILDQLTTIEE 408
>YR831_MIMIV (Q7T6Y2) Putative serine/threonine-protein kinase/receptor R831| precursor (EC 2.7.11.1) Length = 1624 Score = 72.4 bits (176), Expect = 1e-12 Identities = 36/81 (44%), Positives = 50/81 (61%), Gaps = 4/81 (4%) Frame = -2 Query: 640 ADVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNA----HAKLTELLQKC 473 ADV+SFGI+LWELLT + PY+ +TP AV V++ G+RP I A + +L+++C Sbjct: 968 ADVYSFGIILWELLTREQPYKGMTPAAIAVSVIRDGMRPPISDEAVTAHSIEYIDLIKQC 1027 Query: 472 WQQDPAERPDFSEILEALKKI 410 W D RP F EI+ L I Sbjct: 1028 WHSDTIIRPTFLEIMTRLSNI 1048 Score = 67.4 bits (163), Expect = 3e-11 Identities = 29/80 (36%), Positives = 52/80 (65%) Frame = -2 Query: 640 ADVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQD 461 ADVFSFG+++WE+LTGK P+ ++ ++ +++ G RP IP + + +L++KCW Sbjct: 1541 ADVFSFGVVMWEVLTGKEPFAECNFMKVSLDILEGG-RPIIPSDCPHEFAKLIKKCWHAK 1599 Query: 460 PAERPDFSEILEALKKIAEE 401 +RP +E+++ L I E+ Sbjct: 1600 AHKRPTMTEVVQQLMLITEQ 1619
>MLTK_MOUSE (Q9ESL4) Mitogen-activated protein kinase kinase kinase MLT (EC| 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper-and sterile alpha motif kinase ZAK) (Sterile alpha motif- and leucine zipper-containing kinase AZK) ( Length = 802 Score = 72.4 bits (176), Expect = 1e-12 Identities = 31/79 (39%), Positives = 51/79 (64%) Frame = -2 Query: 637 DVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 458 D +S+G++LWE+LT ++P++ L LQ A VV+K R TIP + ELL +CW+ D Sbjct: 188 DTYSYGVVLWEMLTREVPFKGLEGLQVAWLVVEKNERLTIPSSCPRSFAELLHQCWEADA 247 Query: 457 AERPDFSEILEALKKIAEE 401 +RP F +I+ L+ ++ + Sbjct: 248 KKRPSFKQIISILESMSND 266
>MLTK_HUMAN (Q9NYL2) Mitogen-activated protein kinase kinase kinase MLT (EC| 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper-and sterile alpha motif-containing kinase) (Sterile alpha motif- and leucine zipper-containing kinase Length = 800 Score = 72.4 bits (176), Expect = 1e-12 Identities = 31/79 (39%), Positives = 51/79 (64%) Frame = -2 Query: 637 DVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 458 D +S+G++LWE+LT ++P++ L LQ A VV+K R TIP + ELL +CW+ D Sbjct: 188 DTYSYGVVLWEMLTREVPFKGLEGLQVAWLVVEKNERLTIPSSCPRSFAELLHQCWEADA 247 Query: 457 AERPDFSEILEALKKIAEE 401 +RP F +I+ L+ ++ + Sbjct: 248 KKRPSFKQIISILESMSND 266
>ILK1_HUMAN (Q13418) Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59| kDa serine/threonine-protein kinase) (p59ILK) Length = 452 Score = 70.9 bits (172), Expect = 3e-12 Identities = 31/80 (38%), Positives = 54/80 (67%) Frame = -2 Query: 640 ADVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQD 461 AD++SF +LLWEL+T ++P+ L+ ++ + V +GLRPTIP + +L++ C +D Sbjct: 373 ADMWSFAVLLWELVTREVPFADLSNMEIGMKVALEGLRPTIPPGISPHVCKLMKICMNED 432 Query: 460 PAERPDFSEILEALKKIAEE 401 PA+RP F I+ L+K+ ++ Sbjct: 433 PAKRPKFDMIVPILEKMQDK 452
>ILK_MOUSE (O55222) Integrin-linked protein kinase (EC 2.7.11.1)| Length = 452 Score = 70.5 bits (171), Expect = 4e-12 Identities = 30/80 (37%), Positives = 54/80 (67%) Frame = -2 Query: 640 ADVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQD 461 AD++SF +LLWEL+T ++P+ L+ ++ + V +GLRPT+P + +L++ C +D Sbjct: 373 ADMWSFAVLLWELVTREVPFADLSNMEIGMKVALEGLRPTVPPGISPHVCKLMKICMNED 432 Query: 460 PAERPDFSEILEALKKIAEE 401 PA+RP F I+ L+K+ ++ Sbjct: 433 PAKRPKFDMIVPILEKMQDK 452
>ILK2_HUMAN (P57043) Integrin-linked protein kinase 2 (EC 2.7.11.1) (ILK-2)| Length = 452 Score = 67.8 bits (164), Expect = 3e-11 Identities = 30/80 (37%), Positives = 53/80 (66%) Frame = -2 Query: 640 ADVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQD 461 AD++SF +LLWEL+T ++P+ L+ ++ + V +GLRPTIP + +L++ C +D Sbjct: 373 ADMWSFAVLLWELVTREVPFADLSNMEIGMKVALEGLRPTIPPGISPHVCKLMKICMNED 432 Query: 460 PAERPDFSEILEALKKIAEE 401 PA+R F I+ L+K+ ++ Sbjct: 433 PAKRSKFDMIVPILEKMQDK 452
>FGFR4_RAT (Q498D6) Fibroblast growth factor receptor 4 precursor (EC| 2.7.10.1) (FGFR-4) Length = 800 Score = 67.4 bits (163), Expect = 3e-11 Identities = 33/86 (38%), Positives = 56/86 (65%), Gaps = 1/86 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFGILLWE+ T G PY + P++ ++++G R P N ++L L+++CW Sbjct: 668 SDVWSFGILLWEIFTLGGSPYPGI-PVEELFSLLREGHRMERPPNCPSELYGLMRECWHA 726 Query: 463 DPAERPDFSEILEALKKIAEEVGDEH 386 P++RP F +++EAL K+ V +E+ Sbjct: 727 APSQRPTFKQLVEALDKVLLAVSEEY 752
>CSK_CHICK (P41239) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| Length = 450 Score = 66.2 bits (160), Expect = 8e-11 Identities = 34/81 (41%), Positives = 51/81 (62%), Gaps = 1/81 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFGILLWE+ + G++PY + PL+ V V+KG + P A + E+++KCW Sbjct: 367 SDVWSFGILLWEIYSFGRVPYPRI-PLKDVVPRVEKGYKMDPPDGCPAIVYEVMKKCWTL 425 Query: 463 DPAERPDFSEILEALKKIAEE 401 DP RP F ++ E L I E+ Sbjct: 426 DPGHRPSFHQLREQLVHIKEK 446
>TNI3K_RAT (Q7TQP6) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 834 Score = 66.2 bits (160), Expect = 8e-11 Identities = 31/76 (40%), Positives = 47/76 (61%) Frame = -2 Query: 640 ADVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQD 461 ADVFS+ + LWELLTG+IP+ +L P AA + +RP I + ++ LL + W Sbjct: 645 ADVFSYSLCLWELLTGEIPFAHLKPAAAAADMAYHHIRPPIGYSIPKPISSLLIRGWNAC 704 Query: 460 PAERPDFSEILEALKK 413 P RP+FSE++ L++ Sbjct: 705 PEGRPEFSEVVSKLEE 720
>TXK_HUMAN (P42681) Tyrosine-protein kinase TXK (EC 2.7.10.2)| Length = 527 Score = 65.5 bits (158), Expect = 1e-10 Identities = 33/80 (41%), Positives = 51/80 (63%), Gaps = 1/80 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFG+L+WE+ T GK+P+E + LQ V + +G R P A + E++ CW + Sbjct: 447 SDVWSFGVLMWEVFTEGKMPFENKSNLQV-VEAISEGFRLYRPHLAPMSIYEVMYSCWHE 505 Query: 463 DPAERPDFSEILEALKKIAE 404 P RP F+E+L A+ +IAE Sbjct: 506 KPEGRPTFAELLRAVTEIAE 525
>TNI3K_MOUSE (Q5GIG6) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 833 Score = 65.1 bits (157), Expect = 2e-10 Identities = 30/76 (39%), Positives = 46/76 (60%) Frame = -2 Query: 640 ADVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQD 461 ADVFS+ + LWELL G+IP+ +L P AA + +RP I + ++ LL + W Sbjct: 644 ADVFSYALCLWELLIGEIPFAHLKPAAAAADMAYHHIRPPIGYSIPKPISSLLMRGWNAC 703 Query: 460 PAERPDFSEILEALKK 413 P RP+FSE++ L++ Sbjct: 704 PEGRPEFSEVVRKLEE 719
>CTR1_ARATH (Q05609) Serine/threonine-protein kinase CTR1 (EC 2.7.11.1)| Length = 821 Score = 65.1 bits (157), Expect = 2e-10 Identities = 28/77 (36%), Positives = 48/77 (62%) Frame = -2 Query: 640 ADVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQD 461 +DV+SFG++LWEL T + P+ L P Q V K R IP+N + ++ +++ CW + Sbjct: 732 SDVYSFGVILWELATLQQPWGNLNPAQVVAAVGFKCKRLEIPRNLNPQVAAIIEGCWTNE 791 Query: 460 PAERPDFSEILEALKKI 410 P +RP F+ I++ L+ + Sbjct: 792 PWKRPSFATIMDLLRPL 808
>ILK_CAVPO (P57044) Integrin-linked protein kinase (EC 2.7.11.1)| (Beta-integrin-linked kinase) Length = 451 Score = 64.7 bits (156), Expect = 2e-10 Identities = 30/80 (37%), Positives = 53/80 (66%) Frame = -2 Query: 640 ADVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQD 461 AD++SF +LLWEL+T ++P+ L+ ++ + V +G RPTIP + +L++ C +D Sbjct: 373 ADMWSFAVLLWELVTREVPFADLSNMEIGMKVALEG-RPTIPPGISPHVCKLMKICMNED 431 Query: 460 PAERPDFSEILEALKKIAEE 401 PA+RP F I+ L+K+ ++ Sbjct: 432 PAKRPKFDMIVPILEKMQDK 451
>TNI3K_HUMAN (Q59H18) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 936 Score = 64.7 bits (156), Expect = 2e-10 Identities = 30/76 (39%), Positives = 47/76 (61%) Frame = -2 Query: 640 ADVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQD 461 ADVFS+ + LWE+LTG+IP+ +L P AA + +RP I + ++ LL + W Sbjct: 747 ADVFSYALCLWEILTGEIPFAHLKPAAAAADMAYHHIRPPIGYSIPKPISSLLIRGWNAC 806 Query: 460 PAERPDFSEILEALKK 413 P RP+FSE++ L++ Sbjct: 807 PEGRPEFSEVVMKLEE 822
>FGFR4_HUMAN (P22455) Fibroblast growth factor receptor 4 precursor (EC| 2.7.10.1) (FGFR-4) (CD334 antigen) Length = 802 Score = 64.7 bits (156), Expect = 2e-10 Identities = 32/86 (37%), Positives = 55/86 (63%), Gaps = 1/86 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFGILLWE+ T G PY + P++ ++++G R P + +L L+++CW Sbjct: 670 SDVWSFGILLWEIFTLGGSPYPGI-PVEELFSLLREGHRMDRPPHCPPELYGLMRECWHA 728 Query: 463 DPAERPDFSEILEALKKIAEEVGDEH 386 P++RP F +++EAL K+ V +E+ Sbjct: 729 APSQRPTFKQLVEALDKVLLAVSEEY 754
>FGFR4_MOUSE (Q03142) Fibroblast growth factor receptor 4 precursor (EC| 2.7.10.1) (FGFR-4) (Protein-tyrosine kinase receptor MPK-11) Length = 799 Score = 64.3 bits (155), Expect = 3e-10 Identities = 32/86 (37%), Positives = 55/86 (63%), Gaps = 1/86 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SF ILLWE+ T G PY + P++ ++++G R P N ++L L+++CW Sbjct: 667 SDVWSFEILLWEIFTLGGSPYPGI-PVEELFSLLREGHRMERPPNCPSELYGLMRECWHA 725 Query: 463 DPAERPDFSEILEALKKIAEEVGDEH 386 P++RP F +++EAL K+ V +E+ Sbjct: 726 APSQRPTFKQLVEALDKVLLAVSEEY 751
>TXK_MOUSE (P42682) Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18)| (Resting lymphocyte kinase) Length = 527 Score = 63.9 bits (154), Expect = 4e-10 Identities = 32/80 (40%), Positives = 50/80 (62%), Gaps = 1/80 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFG+L+WE+ T GK+P+E + LQ V + +G R P A + ++ CW + Sbjct: 447 SDVWSFGVLMWEVFTEGKMPFENKSNLQV-VEAISQGFRLYRPHLAPMTIYRVMYSCWHE 505 Query: 463 DPAERPDFSEILEALKKIAE 404 P RP F+E+L+ L +IAE Sbjct: 506 SPKGRPTFAELLQVLTEIAE 525
>KYK1_DICDI (P18160) Non-receptor tyrosine kinase spore lysis A (EC 2.7.10.2)| (Tyrosine-protein kinase 1) Length = 1584 Score = 63.5 bits (153), Expect = 5e-10 Identities = 28/80 (35%), Positives = 49/80 (61%) Frame = -2 Query: 640 ADVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQD 461 +DV+S+G++L+ELLT P + + P++ A + RP IP +K E+L +CW + Sbjct: 1486 SDVYSYGMVLFELLTSDEPQQDMKPMKMAHLAAYESYRPPIPLTTSSKWKEILTQCWDSN 1545 Query: 460 PAERPDFSEILEALKKIAEE 401 P RP F +I+ LK++ ++ Sbjct: 1546 PDSRPTFKQIIVHLKEMEDQ 1565
>PTK7_CHICK (Q91048) Tyrosine-protein kinase-like 7 precursor (Kinase-like| protein) Length = 1051 Score = 63.5 bits (153), Expect = 5e-10 Identities = 29/75 (38%), Positives = 47/75 (62%), Gaps = 1/75 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFG+L+WE+ T G++PY L + G+ + P+ ++LT+L+Q+CW Sbjct: 968 SDVWSFGVLMWEVFTQGEMPYAPLADDEVLAGLKSGKTKLPQPEGCPSRLTKLMQRCWAP 1027 Query: 463 DPAERPDFSEILEAL 419 P +RP FSE+ AL Sbjct: 1028 SPKDRPSFSELAAAL 1042
>ITK_MOUSE (Q03526) Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2)| (T-cell-specific kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK) Length = 625 Score = 62.8 bits (151), Expect = 8e-10 Identities = 31/80 (38%), Positives = 51/80 (63%), Gaps = 1/80 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFG+L+WE+ + GKIPYE + + V + G R P+ A + +++ CW++ Sbjct: 544 SDVWSFGVLMWEVFSEGKIPYENRSNSEV-VEDISTGFRLYKPRLASCHVYQIMNHCWKE 602 Query: 463 DPAERPDFSEILEALKKIAE 404 P +RP FS++L L +IAE Sbjct: 603 KPEDRPPFSQLLSQLAEIAE 622
>PHY1_CERPU (P25848) Light-sensor Protein kinase [Includes: Phytochrome; Protein| kinase (EC 2.7.11.1)] Length = 1307 Score = 62.8 bits (151), Expect = 8e-10 Identities = 28/75 (37%), Positives = 46/75 (61%) Frame = -2 Query: 640 ADVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQD 461 +DV+SFG++ +E+LTG +P+ +V +G+RP +P + +L L+ CW QD Sbjct: 1209 SDVYSFGMVCYEVLTGDVPFPEEKNPNNVKRMVLEGVRPDLPAHCPIELKALITDCWNQD 1268 Query: 460 PAERPDFSEILEALK 416 P +RP F+ I + LK Sbjct: 1269 PLKRPSFAVICQKLK 1283
>EPHAA_HUMAN (Q5JZY3) Ephrin type-A receptor 10 precursor (EC 2.7.10.1)| Length = 1008 Score = 62.8 bits (151), Expect = 8e-10 Identities = 32/81 (39%), Positives = 50/81 (61%), Gaps = 1/81 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFGI++WE++ G+ PY ++ Q + V+ G R P+N L L+ CWQ+ Sbjct: 827 SDVWSFGIIMWEVMAFGERPYWDMSG-QDVIKAVEDGFRLPPPRNCPNLLHRLMLDCWQK 885 Query: 463 DPAERPDFSEILEALKKIAEE 401 DP ERP FS+I L K+ ++ Sbjct: 886 DPGERPRFSQIHSILSKMVQD 906
>M3K7_HUMAN (O43318) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1) Length = 606 Score = 62.4 bits (150), Expect = 1e-09 Identities = 27/74 (36%), Positives = 46/74 (62%), Gaps = 1/74 (1%) Frame = -2 Query: 637 DVFSFGILLWELLTGKIPYEYLT-PLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQD 461 DVFS+GI+LWE++T + P++ + P + V G RP + KN + L+ +CW +D Sbjct: 211 DVFSWGIILWEVITRRKPFDEIGGPAFRIMWAVHNGTRPPLIKNLPKPIESLMTRCWSKD 270 Query: 460 PAERPDFSEILEAL 419 P++RP EI++ + Sbjct: 271 PSQRPSMEEIVKIM 284
>ABL2_HUMAN (P42684) Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine| leukemia viral oncogene homolog 2) (Tyrosine kinase ARG) Length = 1182 Score = 62.4 bits (150), Expect = 1e-09 Identities = 34/91 (37%), Positives = 54/91 (59%), Gaps = 7/91 (7%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV++FG+LLWE+ T G PY + L +++KG R P+ K+ EL++ CW+ Sbjct: 466 SDVWAFGVLLWEIATYGMSPYPGID-LSQVYDLLEKGYRMEQPEGCPPKVYELMRACWKW 524 Query: 463 DPAERPDFSEILEALK------KIAEEVGDE 389 PA+RP F+E +A + I+EEV +E Sbjct: 525 SPADRPSFAETHQAFETMFHDSSISEEVAEE 555
>M3K7_MOUSE (Q62073) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1) Length = 579 Score = 62.4 bits (150), Expect = 1e-09 Identities = 27/74 (36%), Positives = 46/74 (62%), Gaps = 1/74 (1%) Frame = -2 Query: 637 DVFSFGILLWELLTGKIPYEYLT-PLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQD 461 DVFS+GI+LWE++T + P++ + P + V G RP + KN + L+ +CW +D Sbjct: 211 DVFSWGIILWEVITRRKPFDEIGGPAFRIMWAVHNGTRPPLIKNLPKPIESLMTRCWSKD 270 Query: 460 PAERPDFSEILEAL 419 P++RP EI++ + Sbjct: 271 PSQRPSMEEIVKIM 284
>TEC_HUMAN (P42680) Tyrosine-protein kinase Tec (EC 2.7.10.2)| Length = 631 Score = 61.6 bits (148), Expect = 2e-09 Identities = 30/80 (37%), Positives = 51/80 (63%), Gaps = 1/80 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFG+L+WE+ T G++P+E T + V +V +G R PK A + E++ +CWQ+ Sbjct: 546 SDVWSFGVLMWEVFTEGRMPFEKYTNYEV-VTMVTRGHRLYQPKLASNYVYEVMLRCWQE 604 Query: 463 DPAERPDFSEILEALKKIAE 404 P RP F ++L + ++ E Sbjct: 605 KPEGRPSFEDLLRTIDELVE 624
>PGFRB_RAT (Q05030) Beta platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-beta) Length = 1097 Score = 61.6 bits (148), Expect = 2e-09 Identities = 30/81 (37%), Positives = 49/81 (60%), Gaps = 1/81 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFGILLWE+ T G PY L +++G R P +A ++ E++QKCW++ Sbjct: 883 SDVWSFGILLWEIFTLGGTPYPELPMNDQFYNAIKRGYRMAQPAHASDEIYEIMQKCWEE 942 Query: 463 DPAERPDFSEILEALKKIAEE 401 RP FS+++ L+++ E Sbjct: 943 KFETRPPFSQLVLLLERLLGE 963
>RON_HUMAN (Q04912) Macrophage-stimulating protein receptor precursor (EC| 2.7.10.1) (MSP receptor) (p185-Ron) (CDw136 antigen) [Contains: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain] Length = 1400 Score = 61.6 bits (148), Expect = 2e-09 Identities = 32/86 (37%), Positives = 51/86 (59%), Gaps = 1/86 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFG+LLWELLT G PY ++ P + Q G R P+ L +++Q+CW+ Sbjct: 1268 SDVWSFGVLLWELLTRGAPPYRHIDPFDLTHFLAQ-GRRLPQPEYCPDSLYQVMQQCWEA 1326 Query: 463 DPAERPDFSEILEALKKIAEEVGDEH 386 DPA RP F ++ +++I + +H Sbjct: 1327 DPAVRPTFRVLVGEVEQIVSALLGDH 1352
>PGFRB_HUMAN (P09619) Beta platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-beta) (CD140b antigen) Length = 1106 Score = 61.6 bits (148), Expect = 2e-09 Identities = 30/81 (37%), Positives = 50/81 (61%), Gaps = 1/81 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFGILLWE+ T G PY L + +++G R P +A ++ E++QKCW++ Sbjct: 884 SDVWSFGILLWEIFTLGGTPYPELPMNEQFYNAIKRGYRMAQPAHASDEIYEIMQKCWEE 943 Query: 463 DPAERPDFSEILEALKKIAEE 401 RP FS+++ L+++ E Sbjct: 944 KFEIRPPFSQLVLLLERLLGE 964
>PGFRB_CANFA (Q6QNF3) Beta platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-beta) Length = 1103 Score = 61.6 bits (148), Expect = 2e-09 Identities = 30/81 (37%), Positives = 50/81 (61%), Gaps = 1/81 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFGILLWE+ T G PY L + +++G R P +A ++ E++QKCW++ Sbjct: 884 SDVWSFGILLWEIFTLGGTPYPELPMNEQFYNAIKRGYRMAQPAHASDEIYEIMQKCWEE 943 Query: 463 DPAERPDFSEILEALKKIAEE 401 RP FS+++ L+++ E Sbjct: 944 KFEIRPPFSQLVLLLERLLGE 964
>PGFRB_MOUSE (P05622) Beta platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-beta) Length = 1098 Score = 61.6 bits (148), Expect = 2e-09 Identities = 30/81 (37%), Positives = 49/81 (60%), Gaps = 1/81 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFGILLWE+ T G PY L +++G R P +A ++ E++QKCW++ Sbjct: 883 SDVWSFGILLWEIFTLGGTPYPELPMNDQFYNAIKRGYRMAQPAHASDEIYEIMQKCWEE 942 Query: 463 DPAERPDFSEILEALKKIAEE 401 RP FS+++ L+++ E Sbjct: 943 KFETRPPFSQLVLLLERLLGE 963
>M3K12_RAT (Q63796) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 888 Score = 61.6 bits (148), Expect = 2e-09 Identities = 28/70 (40%), Positives = 41/70 (58%) Frame = -2 Query: 637 DVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 458 D++SFG++LWELLTG+IPY+ + GV L +P + LL++CW + P Sbjct: 325 DIWSFGVVLWELLTGEIPYKDVDSSAIIWGVGSNSLHLPVPSSCPDGFKILLRQCWNRKP 384 Query: 457 AERPDFSEIL 428 RP F +IL Sbjct: 385 RNRPSFRQIL 394
>M3K12_HUMAN (Q12852) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 859 Score = 61.2 bits (147), Expect = 2e-09 Identities = 28/70 (40%), Positives = 40/70 (57%) Frame = -2 Query: 637 DVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 458 D++SFG++LWELLTG+IPY+ + GV L +P + LL++CW P Sbjct: 292 DIWSFGVVLWELLTGEIPYKDVDSSAIIWGVGSNSLHLPVPSSCPDGFKILLRQCWNSKP 351 Query: 457 AERPDFSEIL 428 RP F +IL Sbjct: 352 RNRPSFRQIL 361
>ITK_HUMAN (Q08881) Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2)| (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT) Length = 620 Score = 61.2 bits (147), Expect = 2e-09 Identities = 31/80 (38%), Positives = 50/80 (62%), Gaps = 1/80 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFG+L+WE+ + GKIPYE + + V + G R P+ A + +++ CW++ Sbjct: 539 SDVWSFGVLMWEVFSEGKIPYENRSNSEV-VEDISTGFRLYKPRLASTHVYQIMNHCWKE 597 Query: 463 DPAERPDFSEILEALKKIAE 404 P +RP FS +L L +IAE Sbjct: 598 RPEDRPAFSRLLRQLAEIAE 617
>M3K12_MOUSE (Q60700) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 888 Score = 61.2 bits (147), Expect = 2e-09 Identities = 28/70 (40%), Positives = 40/70 (57%) Frame = -2 Query: 637 DVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 458 D++SFG++LWELLTG+IPY+ + GV L +P + LL++CW P Sbjct: 325 DIWSFGVVLWELLTGEIPYKDVDSSAIIWGVGSNSLHLPVPSSCPDGFKILLRQCWNSKP 384 Query: 457 AERPDFSEIL 428 RP F +IL Sbjct: 385 RNRPSFRQIL 394
>CSK_HUMAN (P41240) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| (Protein-tyrosine kinase CYL) Length = 450 Score = 60.8 bits (146), Expect = 3e-09 Identities = 31/78 (39%), Positives = 48/78 (61%), Gaps = 1/78 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFGILLWE+ + G++PY + PL+ V V+KG + P + E+++ CW Sbjct: 367 SDVWSFGILLWEIYSFGRVPYPRI-PLKDVVPRVEKGYKMDAPDGCPPAVYEVMKNCWHL 425 Query: 463 DPAERPDFSEILEALKKI 410 D A RP F ++ E L+ I Sbjct: 426 DAAMRPSFLQLREQLEHI 443
>ABL_MLVAB (P00521) Tyrosine-protein kinase transforming protein Abl (EC| 2.7.10.2) (V-abl) Length = 746 Score = 60.8 bits (146), Expect = 3e-09 Identities = 32/87 (36%), Positives = 54/87 (62%), Gaps = 3/87 (3%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV++FG+LLWE+ T G PY + L +++K R P+ K+ EL++ CWQ Sbjct: 306 SDVWAFGVLLWEIATYGMSPYPGID-LSQVYELLEKDYRMERPEGCPEKVYELMRACWQW 364 Query: 463 DPAERPDFSEILEALKKIAEE--VGDE 389 +P++RP F+EI +A + + +E + DE Sbjct: 365 NPSDRPSFAEIHQAFETMFQESSISDE 391
>ABL1_HUMAN (P00519) Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2)| (p150) (c-ABL) (Abelson murine leukemia viral oncogene homolog 1) Length = 1130 Score = 60.8 bits (146), Expect = 3e-09 Identities = 32/87 (36%), Positives = 54/87 (62%), Gaps = 3/87 (3%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV++FG+LLWE+ T G PY + L +++K R P+ K+ EL++ CWQ Sbjct: 420 SDVWAFGVLLWEIATYGMSPYPGID-LSQVYELLEKDYRMERPEGCPEKVYELMRACWQW 478 Query: 463 DPAERPDFSEILEALKKIAEE--VGDE 389 +P++RP F+EI +A + + +E + DE Sbjct: 479 NPSDRPSFAEIHQAFETMFQESSISDE 505
>ABL1_MOUSE (P00520) Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2)| (p150) (c-ABL) (Abelson murine leukemia viral oncogene homolog 1) Length = 1123 Score = 60.8 bits (146), Expect = 3e-09 Identities = 32/87 (36%), Positives = 54/87 (62%), Gaps = 3/87 (3%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV++FG+LLWE+ T G PY + L +++K R P+ K+ EL++ CWQ Sbjct: 420 SDVWAFGVLLWEIATYGMSPYPGID-LSQVYELLEKDYRMERPEGCPEKVYELMRACWQW 478 Query: 463 DPAERPDFSEILEALKKIAEE--VGDE 389 +P++RP F+EI +A + + +E + DE Sbjct: 479 NPSDRPSFAEIHQAFETMFQESSISDE 505
>RON_MOUSE (Q62190) Macrophage-stimulating protein receptor precursor (EC| 2.7.10.1) (MSP receptor) (p185-Ron) (Stem cell-derived tyrosine kinase) (CDw136 antigen) [Contains: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating prote Length = 1378 Score = 60.8 bits (146), Expect = 3e-09 Identities = 34/87 (39%), Positives = 52/87 (59%), Gaps = 2/87 (2%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFG+LLWELLT G PY ++ P + + Q G R P+ L ++ +CW+ Sbjct: 1245 SDVWSFGVLLWELLTRGAPPYPHIDPFDLSHFLAQ-GRRLPQPEYCPDSLYHVMLRCWEA 1303 Query: 463 DPAERPDF-SEILEALKKIAEEVGDEH 386 DPA RP F + +LE + +A +GD + Sbjct: 1304 DPAARPTFRALVLEVKQVVASLLGDHY 1330
>MATK_MOUSE (P41242) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK) Length = 505 Score = 60.5 bits (145), Expect = 4e-09 Identities = 31/83 (37%), Positives = 48/83 (57%), Gaps = 1/83 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFG+LLWE+ + G+ PY ++ L+ V+KG R P + L+ CW+ Sbjct: 403 SDVWSFGVLLWEVFSYGRAPYPKMS-LKEVSEAVEKGYRMEPPDGCPGSVHTLMGSCWEA 461 Query: 463 DPAERPDFSEILEALKKIAEEVG 395 +PA RP F +I+E L + VG Sbjct: 462 EPARRPPFRKIVEKLGRELRSVG 484
>KIT_BOVIN (P43481) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 977 Score = 60.5 bits (145), Expect = 4e-09 Identities = 27/81 (33%), Positives = 50/81 (61%), Gaps = 1/81 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+S+GI LWEL + G PY + ++++G R P++A A++ ++++ CW Sbjct: 851 SDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDA 910 Query: 463 DPAERPDFSEILEALKKIAEE 401 DP +RP F +I++ ++K E Sbjct: 911 DPLKRPTFKQIVQLIEKQISE 931
>KIT_HUMAN (P10721) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen) Length = 976 Score = 60.5 bits (145), Expect = 4e-09 Identities = 27/81 (33%), Positives = 50/81 (61%), Gaps = 1/81 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+S+GI LWEL + G PY + ++++G R P++A A++ ++++ CW Sbjct: 850 SDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDA 909 Query: 463 DPAERPDFSEILEALKKIAEE 401 DP +RP F +I++ ++K E Sbjct: 910 DPLKRPTFKQIVQLIEKQISE 930
>KIT_CAPHI (Q28317) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 978 Score = 60.5 bits (145), Expect = 4e-09 Identities = 27/81 (33%), Positives = 50/81 (61%), Gaps = 1/81 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+S+GI LWEL + G PY + ++++G R P++A A++ ++++ CW Sbjct: 852 SDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDA 911 Query: 463 DPAERPDFSEILEALKKIAEE 401 DP +RP F +I++ ++K E Sbjct: 912 DPLKRPTFKQIVQLIEKQISE 932
>KIT_FSVHZ (P04048) Tyrosine-protein kinase transforming protein kit (EC| 2.7.10.1) Length = 370 Score = 60.1 bits (144), Expect = 5e-09 Identities = 26/77 (33%), Positives = 49/77 (63%), Gaps = 1/77 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+S+GI LWEL + G PY + ++++G R P++A A++ ++++ CW Sbjct: 288 SDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDA 347 Query: 463 DPAERPDFSEILEALKK 413 DP +RP F +I++ ++K Sbjct: 348 DPLKRPTFKQIVQLIEK 364
>LCK_CHICK (P42683) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (Protein-tyrosine kinase C-TKL) (p56tk1) Length = 507 Score = 60.1 bits (144), Expect = 5e-09 Identities = 33/93 (35%), Positives = 57/93 (61%), Gaps = 1/93 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFGILL E++T G+IPY +T + + +++G R P N +L EL+ +CW++ Sbjct: 419 SDVWSFGILLTEIVTYGRIPYPGMTNPEV-IQNLERGYRMPQPDNCPQELYELMMQCWKE 477 Query: 463 DPAERPDFSEILEALKKIAEEVGDEHDGKHKDK 365 P ERP F E +K + E+ +G+++ + Sbjct: 478 QPEERPTF----EYMKSVLEDFFTATEGQYQQQ 506
>BTK_CHICK (Q8JH64) Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton's| tyrosine kinase) Length = 657 Score = 60.1 bits (144), Expect = 5e-09 Identities = 30/81 (37%), Positives = 49/81 (60%), Gaps = 1/81 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFG+L+WE+ + GK+PYE + V+Q GLR P+ A ++ ++ CW + Sbjct: 576 SDVWSFGVLMWEVYSLGKMPYERFNNSETTEHVIQ-GLRLYRPQQASERVYAIMYSCWHE 634 Query: 463 DPAERPDFSEILEALKKIAEE 401 ERP FS +L ++ I +E Sbjct: 635 KAEERPTFSALLGSIVDITDE 655
>FLK_RAT (P09760) Tyrosine-protein kinase FLK (EC 2.7.10.2) (Fragment)| Length = 323 Score = 60.1 bits (144), Expect = 5e-09 Identities = 31/82 (37%), Positives = 49/82 (59%), Gaps = 1/82 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFGILLWE + G PY +T QA V ++G R + P+N ++ ++ KCW Sbjct: 242 SDVWSFGILLWETFSLGVCPYPGMTNQQAREQV-ERGYRMSAPQNCPEEIFTIMMKCWDY 300 Query: 463 DPAERPDFSEILEALKKIAEEV 398 P RP FS++ + L I +++ Sbjct: 301 KPENRPKFSDLHKELTAIKKKI 322
>KIT_FELCA (Q28889) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 978 Score = 60.1 bits (144), Expect = 5e-09 Identities = 26/77 (33%), Positives = 49/77 (63%), Gaps = 1/77 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+S+GI LWEL + G PY + ++++G R P++A A++ ++++ CW Sbjct: 851 SDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDA 910 Query: 463 DPAERPDFSEILEALKK 413 DP +RP F +I++ ++K Sbjct: 911 DPLKRPTFKQIVQLIEK 927
>KIT_CANFA (O97799) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 975 Score = 60.1 bits (144), Expect = 5e-09 Identities = 26/77 (33%), Positives = 49/77 (63%), Gaps = 1/77 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+S+GI LWEL + G PY + ++++G R P++A A++ ++++ CW Sbjct: 849 SDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDA 908 Query: 463 DPAERPDFSEILEALKK 413 DP +RP F +I++ ++K Sbjct: 909 DPLKRPTFKQIVQLIEK 925
>CSK_RAT (P32577) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| Length = 450 Score = 59.7 bits (143), Expect = 7e-09 Identities = 30/78 (38%), Positives = 48/78 (61%), Gaps = 1/78 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFGILLWE+ + G++PY + PL+ V V+KG + P + ++++ CW Sbjct: 367 SDVWSFGILLWEIYSFGRVPYPRI-PLKDVVPRVEKGYKMDAPDGCPPAVYDVMKNCWHL 425 Query: 463 DPAERPDFSEILEALKKI 410 D A RP F ++ E L+ I Sbjct: 426 DAATRPTFLQLREQLEHI 443
>CAD96_DROME (Q9VBW3) Tyrosine kinase receptor Cad96Ca precursor (EC 2.7.10.1)| (Cadherin 96Ca) (Tyrosine kinase receptor HD-14) Length = 773 Score = 59.7 bits (143), Expect = 7e-09 Identities = 29/78 (37%), Positives = 48/78 (61%), Gaps = 1/78 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +D++SFGIL+WE++T G PY ++ + V+ G R P++ +L ++ CW Sbjct: 668 SDIWSFGILMWEIVTLGSTPYPGISAADV-MRKVRDGYRLEKPEHCRRELYNIMYYCWSH 726 Query: 463 DPAERPDFSEILEALKKI 410 DP ERP F+EI++ L K+ Sbjct: 727 DPQERPLFAEIIQMLDKL 744
>TIE2_BRARE (O73791) Tyrosine-protein kinase receptor Tie-2 precursor (EC| 2.7.10.1) Length = 1116 Score = 59.7 bits (143), Expect = 7e-09 Identities = 32/81 (39%), Positives = 52/81 (64%), Gaps = 1/81 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+S+G+LLWE+++ G PY +T + + G R P N ++ EL+Q+CW++ Sbjct: 1011 SDVWSYGVLLWEVVSLGGTPYCGMTCAEL-YEKLPLGFRLEKPLNCDDEVYELMQQCWRE 1069 Query: 463 DPAERPDFSEILEALKKIAEE 401 P ERP FS+IL +L ++ EE Sbjct: 1070 KPFERPSFSQILLSLGRMLEE 1090
>TEC_MOUSE (P24604) Tyrosine-protein kinase Tec (EC 2.7.10.2)| Length = 630 Score = 59.7 bits (143), Expect = 7e-09 Identities = 30/80 (37%), Positives = 50/80 (62%), Gaps = 1/80 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFG+L+WE+ T G++P+E T + V +V +G R PK A L E++ +CWQ+ Sbjct: 545 SDVWSFGVLMWEIFTEGRMPFEKNTNYEV-VTMVTRGHRLHRPKLATKYLYEVMLRCWQE 603 Query: 463 DPAERPDFSEILEALKKIAE 404 P RP ++L + ++ E Sbjct: 604 RPEGRPSLEDLLRTIDELVE 623
>KIT_MOUSE (P05532) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 975 Score = 59.7 bits (143), Expect = 7e-09 Identities = 25/77 (32%), Positives = 49/77 (63%), Gaps = 1/77 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+S+GI LWEL + G PY + ++++G R P++A A++ ++++ CW Sbjct: 848 SDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMVSPEHAPAEMYDVMKTCWDA 907 Query: 463 DPAERPDFSEILEALKK 413 DP +RP F ++++ ++K Sbjct: 908 DPLKRPTFKQVVQLIEK 924
>RET_MOUSE (P35546) Proto-oncogene tyrosine-protein kinase receptor ret| precursor (EC 2.7.10.1) (C-ret) Length = 1115 Score = 59.3 bits (142), Expect = 9e-09 Identities = 31/87 (35%), Positives = 54/87 (62%), Gaps = 1/87 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFG+LLWE++T G PY + P + +++ G R P N ++ L+ +CW+Q Sbjct: 933 SDVWSFGVLLWEIVTLGGNPYPGIPP-ERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQ 991 Query: 463 DPAERPDFSEILEALKKIAEEVGDEHD 383 +P +RP F++I + L+K+ + D D Sbjct: 992 EPDKRPVFADISKDLEKMMVKSRDYLD 1018
>FYN_XIPHE (P27446) Proto-oncogene tyrosine-protein kinase FYN (EC 2.7.10.2)| (P59-FYN) Length = 536 Score = 59.3 bits (142), Expect = 9e-09 Identities = 33/74 (44%), Positives = 50/74 (67%), Gaps = 1/74 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFGILL EL+T G++PY + + + V++G R P++ A L EL+ +CW++ Sbjct: 446 SDVWSFGILLTELVTKGRVPYPGMNNREV-LEQVERGYRMPCPQDCPASLHELMLQCWKK 504 Query: 463 DPAERPDFSEILEA 422 DP ERP F E L+A Sbjct: 505 DPEERPTF-EYLQA 517
>INSRR_CAVPO (P14617) Insulin receptor-related protein precursor (EC 2.7.10.1)| (IRR) (IR-related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain] Length = 1300 Score = 59.3 bits (142), Expect = 9e-09 Identities = 30/77 (38%), Positives = 50/77 (64%), Gaps = 1/77 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFG++LWE++T + PY+ L+ Q V+ G+ + H +L EL+ CWQQ Sbjct: 1173 SDVWSFGVVLWEIVTLAEQPYQGLSNEQVLKFVMDGGVLEELEDCPH-QLQELMSSCWQQ 1231 Query: 463 DPAERPDFSEILEALKK 413 +P RP F++IL +++K Sbjct: 1232 NPRLRPTFTQILNSIQK 1248
>MATK_RAT (P41243) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase BATK) Length = 467 Score = 59.3 bits (142), Expect = 9e-09 Identities = 30/83 (36%), Positives = 49/83 (59%), Gaps = 1/83 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFG+LLWE+ + G+ PY ++ L+ V+KG R P + + L+ CW+ Sbjct: 365 SDVWSFGVLLWEVFSYGRAPYPKMS-LKEVSEAVEKGYRMEPPDSCPGPVHTLMGSCWEA 423 Query: 463 DPAERPDFSEILEALKKIAEEVG 395 +P+ RP F +I+E L + VG Sbjct: 424 EPSRRPPFRKIVEKLGRELRSVG 446
>TIE2_MOUSE (Q02858) Angiopoietin-1 receptor precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen) Length = 1122 Score = 58.9 bits (141), Expect = 1e-08 Identities = 30/81 (37%), Positives = 53/81 (65%), Gaps = 1/81 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+S+G+LLWE+++ G PY +T + + Q G R P N ++ +L+++CW++ Sbjct: 1017 SDVWSYGVLLWEIVSLGGTPYCGMTCAELYEKLPQ-GYRLEKPLNCDDEVYDLMRQCWRE 1075 Query: 463 DPAERPDFSEILEALKKIAEE 401 P ERP F++IL +L ++ EE Sbjct: 1076 KPYERPSFAQILVSLNRMLEE 1096
>TIE2_BOVIN (Q06807) Angiopoietin-1 receptor precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor TIE-2) (CD202b antigen) Length = 1125 Score = 58.9 bits (141), Expect = 1e-08 Identities = 30/81 (37%), Positives = 53/81 (65%), Gaps = 1/81 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+S+G+LLWE+++ G PY +T + + Q G R P N ++ +L+++CW++ Sbjct: 1020 SDVWSYGVLLWEIVSLGGTPYCGMTCAELYEKLPQ-GYRLEKPLNCDDEVYDLMRQCWRE 1078 Query: 463 DPAERPDFSEILEALKKIAEE 401 P ERP F++IL +L ++ EE Sbjct: 1079 KPYERPSFAQILVSLNRMLEE 1099
>VGFR1_RAT (P53767) Vascular endothelial growth factor receptor 1 precursor (EC| 2.7.10.1) (VEGFR-1) (Tyrosine-protein kinase receptor FLT) (FLT-1) Length = 1336 Score = 58.9 bits (141), Expect = 1e-08 Identities = 29/89 (32%), Positives = 54/89 (60%), Gaps = 1/89 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+S+G+LLWE+ + G PY + + +++G+R P+ A ++ +++ CW + Sbjct: 1080 SDVWSYGVLLWEIFSLGGSPYPGVQMDEDFCSRLKEGMRMRTPEYATPEIYQIMLDCWHK 1139 Query: 463 DPAERPDFSEILEALKKIAEEVGDEHDGK 377 DP ERP F+E++E L + + + DGK Sbjct: 1140 DPKERPRFAELVEKLGDLL-QANVQQDGK 1167
>FER_HUMAN (P16591) Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2)| (p94-FER) (c-FER) Length = 822 Score = 58.9 bits (141), Expect = 1e-08 Identities = 31/82 (37%), Positives = 49/82 (59%), Gaps = 1/82 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFGILLWE + G PY +T QA V ++G R + P++ +++++ KCW Sbjct: 741 SDVWSFGILLWETFSLGVCPYPGMTNQQAREQV-ERGYRMSAPQHCPEDISKIMMKCWDY 799 Query: 463 DPAERPDFSEILEALKKIAEEV 398 P RP FSE+ + L I ++ Sbjct: 800 KPENRPKFSELQKELTIIKRKL 821
>VGFR1_MOUSE (P35969) Vascular endothelial growth factor receptor 1 precursor (EC| 2.7.10.1) (VEGFR-1) (Tyrosine-protein kinase receptor FLT) (FLT-1) (Embryonic receptor kinase 2) Length = 1333 Score = 58.9 bits (141), Expect = 1e-08 Identities = 29/89 (32%), Positives = 54/89 (60%), Gaps = 1/89 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+S+G+LLWE+ + G PY + + +++G+R P+ A ++ +++ CW + Sbjct: 1080 SDVWSYGVLLWEIFSLGGSPYPGVQMDEDFCSRLKEGMRMRTPEYATPEIYQIMLDCWHK 1139 Query: 463 DPAERPDFSEILEALKKIAEEVGDEHDGK 377 DP ERP F+E++E L + + + DGK Sbjct: 1140 DPKERPRFAELVEKLGDLL-QANVQQDGK 1167
>RET_HUMAN (P07949) Proto-oncogene tyrosine-protein kinase receptor ret| precursor (EC 2.7.10.1) (C-ret) Length = 1114 Score = 58.9 bits (141), Expect = 1e-08 Identities = 29/78 (37%), Positives = 51/78 (65%), Gaps = 1/78 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFG+LLWE++T G PY + P + +++ G R P N ++ L+ +CW+Q Sbjct: 932 SDVWSFGVLLWEIVTLGGNPYPGIPP-ERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQ 990 Query: 463 DPAERPDFSEILEALKKI 410 +P +RP F++I + L+K+ Sbjct: 991 EPDKRPVFADISKDLEKM 1008
>TIE2_HUMAN (Q02763) Angiopoietin-1 receptor precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen) Length = 1124 Score = 58.9 bits (141), Expect = 1e-08 Identities = 30/81 (37%), Positives = 53/81 (65%), Gaps = 1/81 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+S+G+LLWE+++ G PY +T + + Q G R P N ++ +L+++CW++ Sbjct: 1019 SDVWSYGVLLWEIVSLGGTPYCGMTCAELYEKLPQ-GYRLEKPLNCDDEVYDLMRQCWRE 1077 Query: 463 DPAERPDFSEILEALKKIAEE 401 P ERP F++IL +L ++ EE Sbjct: 1078 KPYERPSFAQILVSLNRMLEE 1098
>IGF1R_HUMAN (P08069) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 recepto Length = 1367 Score = 58.5 bits (140), Expect = 2e-08 Identities = 32/80 (40%), Positives = 49/80 (61%), Gaps = 1/80 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFG++LWE+ T + PY+ L+ Q V++ GL P N L EL++ CWQ Sbjct: 1193 SDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDK-PDNCPDMLFELMRMCWQY 1251 Query: 463 DPAERPDFSEILEALKKIAE 404 +P RP F EI+ ++K+ E Sbjct: 1252 NPKMRPSFLEIISSIKEEME 1271
>EPHA5_CHICK (P54755) Ephrin type-A receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor CEK7) Length = 1013 Score = 58.5 bits (140), Expect = 2e-08 Identities = 30/78 (38%), Positives = 49/78 (62%), Gaps = 1/78 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+S+GI++WE+++ G+ PY +T Q + V++G R P + A L +L+ CWQ+ Sbjct: 835 SDVWSYGIVMWEVMSYGERPYWEMTN-QDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQK 893 Query: 463 DPAERPDFSEILEALKKI 410 D RP F EI+ L K+ Sbjct: 894 DRNSRPKFDEIVSMLDKL 911
>MATK_HUMAN (P42679) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase) Length = 507 Score = 58.5 bits (140), Expect = 2e-08 Identities = 29/83 (34%), Positives = 47/83 (56%), Gaps = 1/83 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFG+LLWE+ + G+ PY ++ L+ V+KG R P+ + L+ CW+ Sbjct: 405 SDVWSFGVLLWEVFSYGRAPYPKMS-LKEVSEAVEKGYRMEPPEGCPGPVHVLMSSCWEA 463 Query: 463 DPAERPDFSEILEALKKIAEEVG 395 +PA RP F ++ E L + G Sbjct: 464 EPARRPPFRKLAEKLARELRSAG 486
>EPHA3_RAT (O08680) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor REK4) (TYRO-4) Length = 984 Score = 58.5 bits (140), Expect = 2e-08 Identities = 30/83 (36%), Positives = 50/83 (60%), Gaps = 1/83 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+S+GI+LWE+++ G+ PY ++ Q + V +G R +P + A L +L+ CWQ+ Sbjct: 806 SDVWSYGIVLWEVMSYGERPYWEMSN-QDVIKAVDEGYRLPLPMDCPAALYQLMLDCWQK 864 Query: 463 DPAERPDFSEILEALKKIAEEVG 395 D RP F +I+ L K+ G Sbjct: 865 DRNNRPKFEQIVSILDKLIRNPG 887
>EPHA7_MOUSE (Q61772) Ephrin type-A receptor 7 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Embryonic brain kinase) (EBK) (Developmental kinase 1) (MDK-1) Length = 998 Score = 58.2 bits (139), Expect = 2e-08 Identities = 29/78 (37%), Positives = 51/78 (65%), Gaps = 1/78 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+S+GI++WE+++ G+ PY ++ Q + +++G R P + A L +L+ CWQ+ Sbjct: 817 SDVWSYGIVMWEVMSYGERPYWDMSN-QDVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQK 875 Query: 463 DPAERPDFSEILEALKKI 410 D AERP F +I+ L K+ Sbjct: 876 DRAERPKFEQIVGILDKM 893
>CEK3_CHICK (P18461) Tyrosine kinase receptor CEK3 precursor (EC 2.7.10.1)| Length = 823 Score = 58.2 bits (139), Expect = 2e-08 Identities = 28/78 (35%), Positives = 50/78 (64%), Gaps = 1/78 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFG+L+WE+ T G PY + P++ ++++G R P N +L +++ CWQ Sbjct: 686 SDVWSFGVLMWEIFTLGGSPYPGI-PVEELFKLLKEGHRMDKPANCTNELYMMMRDCWQA 744 Query: 463 DPAERPDFSEILEALKKI 410 P++RP F +++E L +I Sbjct: 745 VPSQRPTFKQLVEDLDRI 762
>EPHA2_HUMAN (P29317) Ephrin type-A receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) Length = 976 Score = 58.2 bits (139), Expect = 2e-08 Identities = 28/78 (35%), Positives = 50/78 (64%), Gaps = 1/78 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFGI++WE++T G+ PY L+ + + + G R P + + + +L+ +CWQQ Sbjct: 798 SDVWSFGIVMWEVMTYGERPYWELSNHEV-MKAINDGFRLPTPMDCPSAIYQLMMQCWQQ 856 Query: 463 DPAERPDFSEILEALKKI 410 + A RP F++I+ L K+ Sbjct: 857 ERARRPKFADIVSILDKL 874
>EPHA5_MOUSE (Q60629) Ephrin type-A receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Brain-specific kinase) (CEK-7) Length = 877 Score = 58.2 bits (139), Expect = 2e-08 Identities = 30/78 (38%), Positives = 49/78 (62%), Gaps = 1/78 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+S+GI++WE+++ G+ PY +T Q + V++G R P + A L +L+ CWQ+ Sbjct: 698 SDVWSYGIVMWEVVSYGERPYWEMTN-QDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQK 756 Query: 463 DPAERPDFSEILEALKKI 410 D RP F EI+ L K+ Sbjct: 757 DRNSRPKFDEIVNMLDKL 774
>BTKL_DROME (P08630) Tyrosine-protein kinase Btk29A (EC 2.7.10.2) (Dsrc28C)| Length = 786 Score = 58.2 bits (139), Expect = 2e-08 Identities = 28/84 (33%), Positives = 52/84 (61%), Gaps = 1/84 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+++G+L+WE+ T GK+PY L + V VQ+G+ PK+ ++ ++++ CW Sbjct: 704 SDVWAYGVLMWEIFTCGKMPYGRLKNTEV-VERVQRGIILEKPKSCAKEIYDVMKLCWSH 762 Query: 463 DPAERPDFSEILEALKKIAEEVGD 392 P ERP F +++ L +A+ + D Sbjct: 763 GPEERPAFRVLMDQLALVAQTLTD 786
>RYK_MOUSE (Q01887) Tyrosine-protein kinase RYK precursor (EC 2.7.10.1)| (Kinase VIK) (NYK-R) (Met-related kinase) Length = 594 Score = 57.8 bits (138), Expect = 3e-08 Identities = 29/83 (34%), Positives = 48/83 (57%), Gaps = 1/83 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV++FG+ LWEL+T G+ PY + P + A ++ G R P N +L ++ CW Sbjct: 510 SDVWAFGVTLWELMTLGQTPYVDIDPFEMAA-YLKDGYRIAQPINCPDELFAVMACCWAL 568 Query: 463 DPAERPDFSEILEALKKIAEEVG 395 DP ERP F ++++ L + +G Sbjct: 569 DPEERPKFQQLVQCLTEFHAALG 591
>TIE1_BRARE (O73792) Tyrosine-protein kinase receptor Tie-1 (EC 2.7.10.1)| (Fragment) Length = 184 Score = 57.8 bits (138), Expect = 3e-08 Identities = 31/80 (38%), Positives = 50/80 (62%), Gaps = 1/80 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFG+LLWE+++ G PY +T + + Q G R P+N ++ EL+++CW+ Sbjct: 80 SDVWSFGVLLWEIVSLGGTPYCGMTCAELYEKLPQ-GYRMEQPRNCDDEVYELMRQCWRD 138 Query: 463 DPAERPDFSEILEALKKIAE 404 P ERP FS+I L ++ E Sbjct: 139 RPYERPPFSQISVQLNRMQE 158
>EPA4A_BRARE (O13148) Ephrin type-A receptor 4a (EC 2.7.10.1) (Tyrosine-protein| kinase receptor ZEK2) (EPH-like kinase 2) (Fragment) Length = 292 Score = 57.8 bits (138), Expect = 3e-08 Identities = 28/78 (35%), Positives = 51/78 (65%), Gaps = 1/78 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+S+GI++WE+++ G+ PY ++ Q + +++G R P + L +L+ CWQ+ Sbjct: 188 SDVWSYGIVMWEVMSYGERPYWDMSN-QDVIKAIEEGYRLPPPMDCPVSLHQLMLDCWQK 246 Query: 463 DPAERPDFSEILEALKKI 410 + AERP FS+I+ L K+ Sbjct: 247 ERAERPKFSQIVNMLDKL 264
>RYK_HUMAN (P34925) Tyrosine-protein kinase RYK precursor (EC 2.7.10.1)| Length = 604 Score = 57.8 bits (138), Expect = 3e-08 Identities = 29/83 (34%), Positives = 48/83 (57%), Gaps = 1/83 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV++FG+ LWEL+T G+ PY + P + A ++ G R P N +L ++ CW Sbjct: 520 SDVWAFGVTLWELMTLGQTPYVDIDPFEMAA-YLKDGYRIAQPINCPDELFAVMACCWAL 578 Query: 463 DPAERPDFSEILEALKKIAEEVG 395 DP ERP F ++++ L + +G Sbjct: 579 DPEERPKFQQLVQCLTEFHAALG 601
>VGFR1_HUMAN (P17948) Vascular endothelial growth factor receptor 1 precursor (EC| 2.7.10.1) (VEGFR-1) (Vascular permeability factor receptor) (Tyrosine-protein kinase receptor FLT) (Flt-1) (Tyrosine-protein kinase FRT) (Fms-like tyrosine kinase 1) Length = 1338 Score = 57.8 bits (138), Expect = 3e-08 Identities = 28/89 (31%), Positives = 54/89 (60%), Gaps = 1/89 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+S+G+LLWE+ + G PY + + +++G+R P+ + ++ +++ CW + Sbjct: 1080 SDVWSYGVLLWEIFSLGGSPYPGVQMDEDFCSRLREGMRMRAPEYSTPEIYQIMLDCWHR 1139 Query: 463 DPAERPDFSEILEALKKIAEEVGDEHDGK 377 DP ERP F+E++E L + + + DGK Sbjct: 1140 DPKERPRFAELVEKLGDLL-QANVQQDGK 1167
>FGFR1_XENLA (P22182) Fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) (FGFR-1) Length = 812 Score = 57.4 bits (137), Expect = 4e-08 Identities = 28/78 (35%), Positives = 50/78 (64%), Gaps = 1/78 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFG+LLWE+ T G PY + P++ ++++G R P N +L +++ CW Sbjct: 675 SDVWSFGVLLWEIFTLGGSPYPGV-PMEELFKLLKEGHRMDKPTNCTNELYMMMKDCWHA 733 Query: 463 DPAERPDFSEILEALKKI 410 P++RP F++++E L +I Sbjct: 734 MPSQRPTFNQLVEDLDRI 751
>RYK1_DROME (Q27324) Tyrosine-protein kinase Drl precursor (EC 2.7.10.1)| (Protein derailed) Length = 610 Score = 57.4 bits (137), Expect = 4e-08 Identities = 29/82 (35%), Positives = 47/82 (57%), Gaps = 1/82 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFG+L+WE+ T GK+PY + P + ++ G R P N +L ++ CW Sbjct: 526 SDVWSFGVLMWEMCTLGKLPYAEIDPYEME-HYLKDGYRLAQPFNCPDELFTIMAYCWAS 584 Query: 463 DPAERPDFSEILEALKKIAEEV 398 PAERP FS++ L + ++ Sbjct: 585 MPAERPSFSQLQICLSEFHTQI 606
>IGF1R_BOVIN (Q05688) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] (F Length = 640 Score = 57.4 bits (137), Expect = 4e-08 Identities = 31/76 (40%), Positives = 47/76 (61%), Gaps = 1/76 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFG++LWE+ T + PY+ L+ Q V++ GL P N L EL++ CWQ Sbjct: 466 SDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDK-PDNCPDMLFELMRMCWQY 524 Query: 463 DPAERPDFSEILEALK 416 +P RP F EI+ ++K Sbjct: 525 NPKMRPSFLEIISSVK 540
>SRC42_DROME (Q9V9J3) Tyrosine-protein kinase Src42A (EC 2.7.10.2) (Dsrc41)| Length = 517 Score = 57.4 bits (137), Expect = 4e-08 Identities = 30/71 (42%), Positives = 43/71 (60%), Gaps = 1/71 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFGILL EL+T G+IPY +T + V + G R P N +L E++ +CW + Sbjct: 427 SDVWSFGILLTELVTYGRIPYPGMTNAEVLTQV-EHGYRMPQPPNCEPRLYEIMLECWHK 485 Query: 463 DPAERPDFSEI 431 DP RP F + Sbjct: 486 DPMRRPTFETL 496
>YES_AVISY (P00527) Tyrosine-protein kinase transforming protein YES (EC| 2.7.10.2) (Fragment) Length = 528 Score = 57.0 bits (136), Expect = 5e-08 Identities = 31/76 (40%), Positives = 47/76 (61%), Gaps = 1/76 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFGILL EL+T G++PY + + + V++G R P+ L EL++ CW++ Sbjct: 443 SDVWSFGILLTELVTKGRVPYPGMVNREV-LEQVERGYRMPCPQGCPESLHELMKLCWKK 501 Query: 463 DPAERPDFSEILEALK 416 DP ERP F I L+ Sbjct: 502 DPDERPTFEYIQSFLE 517
>FGFR1_CHICK (P21804) Basic fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) Length = 819 Score = 57.0 bits (136), Expect = 5e-08 Identities = 28/78 (35%), Positives = 49/78 (62%), Gaps = 1/78 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFG+LLWE+ T G PY + P++ ++++G R P N +L +++ CW Sbjct: 679 SDVWSFGVLLWEIFTLGGSPYPGV-PVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHA 737 Query: 463 DPAERPDFSEILEALKKI 410 P++RP F +++E L +I Sbjct: 738 VPSQRPTFKQLVEDLDRI 755
>YES_CHICK (P09324) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 540 Score = 57.0 bits (136), Expect = 5e-08 Identities = 31/76 (40%), Positives = 47/76 (61%), Gaps = 1/76 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFGILL EL+T G++PY + + + V++G R P+ L EL++ CW++ Sbjct: 450 SDVWSFGILLTELVTKGRVPYPGMVNREV-LEQVERGYRMPCPQGCPESLHELMKLCWKK 508 Query: 463 DPAERPDFSEILEALK 416 DP ERP F I L+ Sbjct: 509 DPDERPTFEYIQSFLE 524
>FGFR1_MOUSE (P16092) Basic fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) (FGFR-1) (bFGF-R) (MFR) Length = 822 Score = 57.0 bits (136), Expect = 5e-08 Identities = 28/78 (35%), Positives = 49/78 (62%), Gaps = 1/78 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFG+LLWE+ T G PY + P++ ++++G R P N +L +++ CW Sbjct: 681 SDVWSFGVLLWEIFTLGGSPYPGV-PVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHA 739 Query: 463 DPAERPDFSEILEALKKI 410 P++RP F +++E L +I Sbjct: 740 VPSQRPTFKQLVEDLDRI 757
>FGFR1_HUMAN (P11362) Basic fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) (FGFR-1) (bFGF-R) (Fms-like tyrosine kinase 2) (c-fgr) (CD331 antigen) Length = 822 Score = 57.0 bits (136), Expect = 5e-08 Identities = 28/78 (35%), Positives = 49/78 (62%), Gaps = 1/78 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFG+LLWE+ T G PY + P++ ++++G R P N +L +++ CW Sbjct: 681 SDVWSFGVLLWEIFTLGGSPYPGV-PVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHA 739 Query: 463 DPAERPDFSEILEALKKI 410 P++RP F +++E L +I Sbjct: 740 VPSQRPTFKQLVEDLDRI 757
>EPHA5_RAT (P54757) Ephrin type-A receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) Length = 1005 Score = 57.0 bits (136), Expect = 5e-08 Identities = 29/78 (37%), Positives = 49/78 (62%), Gaps = 1/78 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+S+GI++WE+++ G+ PY +T Q + V++G R P + A L +L+ CWQ+ Sbjct: 861 SDVWSYGIVMWEVVSYGERPYWEMTN-QDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQK 919 Query: 463 DPAERPDFSEILEALKKI 410 D RP F +I+ L K+ Sbjct: 920 DRNSRPKFDDIVNMLDKL 937
>INSR_AEDAE (Q93105) Insulin-like receptor precursor (EC 2.7.10.1) (MIR)| [Contains: Insulin-like receptor alpha chain; Insulin-like receptor beta chain] Length = 1390 Score = 57.0 bits (136), Expect = 5e-08 Identities = 30/75 (40%), Positives = 43/75 (57%), Gaps = 1/75 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DVFS+G++LWE+ T PY+ LT Q V+ G+ P+N L L+++CWQ Sbjct: 1220 SDVFSYGVVLWEMATLASQPYQGLTNDQVLRYVIDGGVMER-PENCPDNLYNLMRRCWQH 1278 Query: 463 DPAERPDFSEILEAL 419 P RP F EI+ L Sbjct: 1279 RPTARPTFMEIISEL 1293
>IGF1R_MOUSE (Q60751) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] Length = 1373 Score = 57.0 bits (136), Expect = 5e-08 Identities = 31/76 (40%), Positives = 47/76 (61%), Gaps = 1/76 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFG++LWE+ T + PY+ L+ Q V++ GL P N L EL++ CWQ Sbjct: 1195 SDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDK-PDNCPDMLFELMRMCWQY 1253 Query: 463 DPAERPDFSEILEALK 416 +P RP F EI+ ++K Sbjct: 1254 NPKMRPSFLEIIGSIK 1269
>FGFR3_HUMAN (P22607) Fibroblast growth factor receptor 3 precursor (EC| 2.7.10.1) (FGFR-3) (CD333 antigen) Length = 806 Score = 57.0 bits (136), Expect = 5e-08 Identities = 27/78 (34%), Positives = 49/78 (62%), Gaps = 1/78 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFG+LLWE+ T G PY + P++ ++++G R P N L ++++CW Sbjct: 675 SDVWSFGVLLWEIFTLGGSPYPGI-PVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHA 733 Query: 463 DPAERPDFSEILEALKKI 410 P++RP F +++E L ++ Sbjct: 734 APSQRPTFKQLVEDLDRV 751
>IGF1R_RAT (P24062) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] Length = 1370 Score = 57.0 bits (136), Expect = 5e-08 Identities = 31/76 (40%), Positives = 47/76 (61%), Gaps = 1/76 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFG++LWE+ T + PY+ L+ Q V++ GL P N L EL++ CWQ Sbjct: 1194 SDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDK-PDNCPDMLFELMRMCWQY 1252 Query: 463 DPAERPDFSEILEALK 416 +P RP F EI+ ++K Sbjct: 1253 NPKMRPSFLEIIGSIK 1268
>EPHA7_RAT (P54759) Ephrin type-A receptor 7 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) Length = 998 Score = 56.6 bits (135), Expect = 6e-08 Identities = 28/78 (35%), Positives = 51/78 (65%), Gaps = 1/78 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+S+GI++WE+++ G+ PY ++ Q + +++G R P + A L +L+ CWQ+ Sbjct: 817 SDVWSYGIVMWEVMSYGERPYWDMSN-QDVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQK 875 Query: 463 DPAERPDFSEILEALKKI 410 + AERP F +I+ L K+ Sbjct: 876 ERAERPKFEQIVGILDKM 893
>EPHA7_HUMAN (Q15375) Ephrin type-A receptor 7 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Receptor protein-tyrosine kinase HEK11) Length = 998 Score = 56.6 bits (135), Expect = 6e-08 Identities = 28/78 (35%), Positives = 51/78 (65%), Gaps = 1/78 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+S+GI++WE+++ G+ PY ++ Q + +++G R P + A L +L+ CWQ+ Sbjct: 817 SDVWSYGIVMWEVMSYGERPYWDMSN-QDVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQK 875 Query: 463 DPAERPDFSEILEALKKI 410 + AERP F +I+ L K+ Sbjct: 876 ERAERPKFEQIVGILDKM 893
>ANKK1_HUMAN (Q8NFD2) Ankyrin repeat and protein kinase domain-containing| protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288) Length = 765 Score = 56.6 bits (135), Expect = 6e-08 Identities = 29/76 (38%), Positives = 45/76 (59%), Gaps = 7/76 (9%) Frame = -2 Query: 637 DVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTI-------PKNAHAKLTELLQ 479 DV+SF I++WELLT K PY + + V G+RP++ P A ++ +L++ Sbjct: 208 DVYSFAIVIWELLTQKKPYSGFNMMMIIIRVA-AGMRPSLQPVSDQWPSEAQ-QMVDLMK 265 Query: 478 KCWQQDPAERPDFSEI 431 +CW QDP +RP F +I Sbjct: 266 RCWDQDPKKRPCFLDI 281
>EPHA5_HUMAN (P54756) Ephrin type-A receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Receptor protein-tyrosine kinase HEK7) Length = 1037 Score = 56.6 bits (135), Expect = 6e-08 Identities = 29/78 (37%), Positives = 49/78 (62%), Gaps = 1/78 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+S+GI++WE+++ G+ PY +T Q + V++G R P + A L +L+ CWQ+ Sbjct: 859 SDVWSYGIVMWEVVSYGERPYWEMTN-QDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQK 917 Query: 463 DPAERPDFSEILEALKKI 410 + RP F EI+ L K+ Sbjct: 918 ERNSRPKFDEIVNMLDKL 935
>M3K13_PONPY (Q5R8X7) Mitogen-activated protein kinase kinase kinase 13 (EC| 2.7.11.25) Length = 966 Score = 56.6 bits (135), Expect = 6e-08 Identities = 28/80 (35%), Positives = 42/80 (52%) Frame = -2 Query: 637 DVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 458 D++SFG++LWELLTG+IPY+ + GV L +P L+++ WQ P Sbjct: 335 DIWSFGVVLWELLTGEIPYKDVDSSAIIWGVGSNSLHLPVPSTCPDGFKILMKQTWQSKP 394 Query: 457 AERPDFSEILEALKKIAEEV 398 RP F + L L + +V Sbjct: 395 RNRPSFRQTLMHLDIASADV 414
>M3K13_HUMAN (O43283) Mitogen-activated protein kinase kinase kinase 13 (EC| 2.7.11.25) (Mixed lineage kinase) (MLK) (Leucine zipper-bearing kinase) Length = 966 Score = 56.6 bits (135), Expect = 6e-08 Identities = 28/80 (35%), Positives = 42/80 (52%) Frame = -2 Query: 637 DVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 458 D++SFG++LWELLTG+IPY+ + GV L +P L+++ WQ P Sbjct: 335 DIWSFGVVLWELLTGEIPYKDVDSSAIIWGVGSNSLHLPVPSTCPDGFKILMKQTWQSKP 394 Query: 457 AERPDFSEILEALKKIAEEV 398 RP F + L L + +V Sbjct: 395 RNRPSFRQTLMHLDIASADV 414
>FPS_AVISP (P00541) Tyrosine-protein kinase transforming protein Fps (EC| 2.7.10.2) Length = 533 Score = 56.6 bits (135), Expect = 6e-08 Identities = 29/75 (38%), Positives = 43/75 (57%), Gaps = 1/75 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFGILLWE + G +PY L+ Q + Q G+R P+ + L+Q+CW+ Sbjct: 452 SDVWSFGILLWEAFSLGAVPYANLSNQQTREAIEQ-GVRLEPPEQCPEDVYRLMQRCWEY 510 Query: 463 DPAERPDFSEILEAL 419 DP RP F + + L Sbjct: 511 DPRRRPSFGAVHQDL 525
>EPHA8_RAT (P29321) Ephrin type-A receptor 8 (EC 2.7.10.1) (Tyrosine-protein| kinase receptor EEK) (EPH- and ELK-related kinase) (Fragment) Length = 372 Score = 56.6 bits (135), Expect = 6e-08 Identities = 28/78 (35%), Positives = 47/78 (60%), Gaps = 1/78 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFG+++WE+L G+ PY +T Q + V++G R P L +L+ CW + Sbjct: 186 SDVWSFGVVMWEVLAYGERPYWNMTN-QDVISSVEEGYRLPAPMGCPRALHQLMLDCWHK 244 Query: 463 DPAERPDFSEILEALKKI 410 D A+RP FS ++ L+ + Sbjct: 245 DRAQRPRFSHVVSVLEAL 262
>CEK2_CHICK (P18460) Tyrosine kinase receptor CEK2 precursor (EC 2.7.10.1)| Length = 806 Score = 56.6 bits (135), Expect = 6e-08 Identities = 27/78 (34%), Positives = 49/78 (62%), Gaps = 1/78 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFG+LLWE+ T G PY + P++ ++++G R P N L ++++CW Sbjct: 669 SDVWSFGVLLWEIFTLGGSPYPGI-PVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHA 727 Query: 463 DPAERPDFSEILEALKKI 410 P++RP F +++E L ++ Sbjct: 728 VPSQRPTFKQLVEDLDRV 745
>EPHA3_HUMAN (P29320) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ETK1) (HEK) (HEK4) Length = 983 Score = 56.6 bits (135), Expect = 6e-08 Identities = 30/83 (36%), Positives = 49/83 (59%), Gaps = 1/83 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+S+GI+LWE+++ G+ PY ++ Q + V +G R P + A L +L+ CWQ+ Sbjct: 805 SDVWSYGIVLWEVMSYGERPYWEMSN-QDVIKAVDEGYRLPPPMDCPAALYQLMLDCWQK 863 Query: 463 DPAERPDFSEILEALKKIAEEVG 395 D RP F +I+ L K+ G Sbjct: 864 DRNNRPKFEQIVSILDKLIRNPG 886
>ANKK1_MOUSE (Q8BZ25) Ankyrin repeat and protein kinase domain-containing| protein 1 (EC 2.7.11.1) Length = 745 Score = 56.6 bits (135), Expect = 6e-08 Identities = 28/76 (36%), Positives = 45/76 (59%), Gaps = 7/76 (9%) Frame = -2 Query: 637 DVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTI-------PKNAHAKLTELLQ 479 DV+SF I++WE+LT K PY L + + V G+RP++ P+ H ++ L++ Sbjct: 220 DVYSFAIVIWEILTQKKPYAGLNMMTIIIRVA-AGMRPSLQDVSDEWPEEVH-QMVNLMK 277 Query: 478 KCWQQDPAERPDFSEI 431 +CW QDP +RP F + Sbjct: 278 RCWDQDPKKRPCFLNV 293
>ROS_HUMAN (P08922) Proto-oncogene tyrosine-protein kinase ROS precursor (EC| 2.7.10.1) (c-ros-1) Length = 2347 Score = 56.6 bits (135), Expect = 6e-08 Identities = 32/76 (42%), Positives = 44/76 (57%), Gaps = 1/76 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFGIL+WE+LT G PY + L + VQ G R P+N L L+ +CW Q Sbjct: 2142 SDVWSFGILIWEILTLGHQPYPAHSNLDV-LNYVQTGGRLEPPRNCPDDLWNLMTQCWAQ 2200 Query: 463 DPAERPDFSEILEALK 416 +P +RP F I L+ Sbjct: 2201 EPDQRPTFHRIQNQLQ 2216
>IGF1R_XENLA (O73798) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (xIGF-1R) (xIGFR) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] Length = 1358 Score = 56.2 bits (134), Expect = 8e-08 Identities = 30/76 (39%), Positives = 47/76 (61%), Gaps = 1/76 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFG++LWE+ T + PY+ ++ Q V++ GL P N L EL++ CWQ Sbjct: 1189 SDVWSFGVVLWEIATLAEQPYQGMSNEQVLRFVMEGGLLEK-PDNCPDMLFELMRMCWQF 1247 Query: 463 DPAERPDFSEILEALK 416 +P RP F EI+ ++K Sbjct: 1248 NPKMRPSFLEIISSIK 1263
>VGFR2_MOUSE (P35918) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Protein-tyrosine kinase receptor flk-1) (Fetal liver kinase 1) (Kinase NYK) Length = 1367 Score = 56.2 bits (134), Expect = 8e-08 Identities = 29/89 (32%), Positives = 50/89 (56%), Gaps = 1/89 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFG+LLWE+ + G PY + + +++G R P ++ + + CW + Sbjct: 1084 SDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHE 1143 Query: 463 DPAERPDFSEILEALKKIAEEVGDEHDGK 377 DP +RP FSE++E L + + + DGK Sbjct: 1144 DPNQRPSFSELVEHLGNLL-QANAQQDGK 1171
>FAK1_HUMAN (Q05397) Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK)| (Protein-tyrosine kinase 2) Length = 1052 Score = 56.2 bits (134), Expect = 8e-08 Identities = 29/81 (35%), Positives = 45/81 (55%), Gaps = 1/81 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+ FG+ +WE+L G P++ + +G ++ G R +P N L L+ KCW Sbjct: 603 SDVWMFGVCMWEILMHGVKPFQGVKN-NDVIGRIENGERLPMPPNCPPTLYSLMTKCWAY 661 Query: 463 DPAERPDFSEILEALKKIAEE 401 DP+ RP F+E+ L I EE Sbjct: 662 DPSRRPRFTELKAQLSTILEE 682
>ABL_FSVHY (P10447) Tyrosine-protein kinase transforming protein Abl (EC| 2.7.10.2) (V-abl) Length = 439 Score = 56.2 bits (134), Expect = 8e-08 Identities = 28/71 (39%), Positives = 45/71 (63%), Gaps = 1/71 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV++FG+LLWE+ T G PY + L +++K R P+ K+ EL++ CWQ Sbjct: 369 SDVWAFGVLLWEIATYGMSPYPGID-LSQVYELLEKDYRMERPEGCPEKVYELMRACWQW 427 Query: 463 DPAERPDFSEI 431 +P++RP F+EI Sbjct: 428 NPSDRPAFAEI 438
>FYN_XENLA (P13406) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 536 Score = 56.2 bits (134), Expect = 8e-08 Identities = 29/68 (42%), Positives = 44/68 (64%), Gaps = 1/68 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFGILL EL+T G++PY + + + V++G R P++ L EL+ CW++ Sbjct: 446 SDVWSFGILLTELVTKGRVPYPGMNNREV-LEQVERGYRMPCPQDCPISLHELMLNCWKK 504 Query: 463 DPAERPDF 440 DP ERP F Sbjct: 505 DPEERPTF 512
>FAK1_XENLA (Q91738) Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK)| Length = 1068 Score = 56.2 bits (134), Expect = 8e-08 Identities = 29/81 (35%), Positives = 45/81 (55%), Gaps = 1/81 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+ FG+ +WE+L G P++ + +G ++ G R +P N L L+ KCW Sbjct: 616 SDVWMFGVCMWEILMYGVKPFQGVKN-NDVIGRIENGERLPMPPNCPPTLYSLMTKCWAY 674 Query: 463 DPAERPDFSEILEALKKIAEE 401 DP+ RP F+E+ L I EE Sbjct: 675 DPSRRPRFTELKAQLSTILEE 695
>FPS_FUJSV (P00530) Tyrosine-protein kinase transforming protein FPS (EC| 2.7.10.2) Length = 873 Score = 56.2 bits (134), Expect = 8e-08 Identities = 29/75 (38%), Positives = 43/75 (57%), Gaps = 1/75 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFGILLWE + G +PY L+ Q + Q G+R P+ + L+Q+CW+ Sbjct: 792 SDVWSFGILLWEAFSLGAVPYANLSNQQTREAIEQ-GVRLEPPEQCPEDVYRLMQRCWEY 850 Query: 463 DPAERPDFSEILEAL 419 DP RP F + + L Sbjct: 851 DPHRRPSFGAVHQDL 865
>FAK1_CHICK (Q00944) Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK)| Length = 1053 Score = 56.2 bits (134), Expect = 8e-08 Identities = 29/81 (35%), Positives = 45/81 (55%), Gaps = 1/81 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+ FG+ +WE+L G P++ + +G ++ G R +P N L L+ KCW Sbjct: 603 SDVWMFGVCMWEILMHGVKPFQGVKN-NDVIGRIENGERLPMPPNCPPTLYSLMTKCWAY 661 Query: 463 DPAERPDFSEILEALKKIAEE 401 DP+ RP F+E+ L I EE Sbjct: 662 DPSRRPRFTELKAQLSTILEE 682
>BTK_HUMAN (Q06187) Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton's| tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) Length = 658 Score = 56.2 bits (134), Expect = 8e-08 Identities = 28/81 (34%), Positives = 47/81 (58%), Gaps = 1/81 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +D+++FG+L+WE+ + GK+PYE T + A + Q GLR P A K+ ++ CW + Sbjct: 577 SDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQ-GLRLYRPHLASEKVYTIMYSCWHE 635 Query: 463 DPAERPDFSEILEALKKIAEE 401 ERP F +L + + +E Sbjct: 636 KADERPTFKILLSNILDVMDE 656
>FGFR2_MOUSE (P21803) Fibroblast growth factor receptor 2 precursor (EC| 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor) Length = 821 Score = 56.2 bits (134), Expect = 8e-08 Identities = 27/78 (34%), Positives = 49/78 (62%), Gaps = 1/78 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFG+L+WE+ T G PY + P++ ++++G R P N +L +++ CW Sbjct: 684 SDVWSFGVLMWEIFTLGGSPYPGI-PVEELFKLLKEGHRMDKPTNCTNELYMMMRDCWHA 742 Query: 463 DPAERPDFSEILEALKKI 410 P++RP F +++E L +I Sbjct: 743 VPSQRPTFKQLVEDLDRI 760
>FGFR2_HUMAN (P21802) Fibroblast growth factor receptor 2 precursor (EC| 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor 2) (CD332 antigen) Length = 821 Score = 56.2 bits (134), Expect = 8e-08 Identities = 27/78 (34%), Positives = 49/78 (62%), Gaps = 1/78 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFG+L+WE+ T G PY + P++ ++++G R P N +L +++ CW Sbjct: 684 SDVWSFGVLMWEIFTLGGSPYPGI-PVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHA 742 Query: 463 DPAERPDFSEILEALKKI 410 P++RP F +++E L +I Sbjct: 743 VPSQRPTFKQLVEDLDRI 760
>FAK1_MOUSE (P34152) Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK)| Length = 1090 Score = 56.2 bits (134), Expect = 8e-08 Identities = 29/81 (35%), Positives = 45/81 (55%), Gaps = 1/81 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+ FG+ +WE+L G P++ + +G ++ G R +P N L L+ KCW Sbjct: 641 SDVWMFGVCMWEILMHGVKPFQGVKN-NDVIGRIENGERLPMPPNCPPTLYSLMTKCWAY 699 Query: 463 DPAERPDFSEILEALKKIAEE 401 DP+ RP F+E+ L I EE Sbjct: 700 DPSRRPRFTELKAQLSTILEE 720
>FAK1_RAT (O35346) Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK)| Length = 1055 Score = 56.2 bits (134), Expect = 8e-08 Identities = 29/81 (35%), Positives = 45/81 (55%), Gaps = 1/81 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+ FG+ +WE+L G P++ + +G ++ G R +P N L L+ KCW Sbjct: 603 SDVWMFGVCMWEILMHGVKPFQGVKN-NDVIGRIENGERLPMPPNCPPTLYSLMTKCWAY 661 Query: 463 DPAERPDFSEILEALKKIAEE 401 DP+ RP F+E+ L I EE Sbjct: 662 DPSRRPRFTELKAQLSTILEE 682
>EPHA2_MOUSE (Q03145) Ephrin type-A receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2) Length = 977 Score = 55.8 bits (133), Expect = 1e-07 Identities = 26/78 (33%), Positives = 50/78 (64%), Gaps = 1/78 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+S+GI++WE++T G+ PY L+ + + + G R P + + + +L+ +CWQQ Sbjct: 799 SDVWSYGIVMWEVMTYGERPYWELSNHEV-MKAINDGFRLPTPMDCPSAIYQLMMQCWQQ 857 Query: 463 DPAERPDFSEILEALKKI 410 + + RP F++I+ L K+ Sbjct: 858 ERSRRPKFADIVSILDKL 875
>FES_MOUSE (P16879) Proto-oncogene tyrosine-protein kinase Fes/Fps (EC| 2.7.10.2) (C-Fes) Length = 820 Score = 55.8 bits (133), Expect = 1e-07 Identities = 32/78 (41%), Positives = 44/78 (56%), Gaps = 1/78 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFGILLWE + G PY LT Q V+KG R P+ + L+++CW Sbjct: 739 SDVWSFGILLWETFSLGASPYPNLTNQQTRE-FVEKGHRLPCPELCPDAVFRLMEQCWAY 797 Query: 463 DPAERPDFSEILEALKKI 410 +P +RP FS I + L I Sbjct: 798 EPGQRPSFSIICQELHSI 815
>FYN_HUMAN (P06241) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) (Protooncogene Syn) (SLK) Length = 536 Score = 55.8 bits (133), Expect = 1e-07 Identities = 30/76 (39%), Positives = 47/76 (61%), Gaps = 1/76 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFGILL EL+T G++PY + + + V++G R P++ L EL+ CW++ Sbjct: 446 SDVWSFGILLTELVTKGRVPYPGMNNREV-LEQVERGYRMPCPQDCPISLHELMIHCWKK 504 Query: 463 DPAERPDFSEILEALK 416 DP ERP F + L+ Sbjct: 505 DPEERPTFEYLQSFLE 520
>VGFR2_BRARE (Q8AXB3) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Receptor tyrosine kinase flk-1) Length = 1302 Score = 55.8 bits (133), Expect = 1e-07 Identities = 27/90 (30%), Positives = 54/90 (60%), Gaps = 1/90 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFG+L+WE+ + G PY L + +++G R P+ + +++ + + CW Sbjct: 1061 SDVWSFGVLMWEIFSLGASPYPGLHIDEEFCCRLKEGTRMKAPEYSSSEIYQTMLDCWHG 1120 Query: 463 DPAERPDFSEILEALKKIAEEVGDEHDGKH 374 +P++RP F+E++E L + + + +GKH Sbjct: 1121 EPSQRPTFTELVERLGDLL-QASVQQEGKH 1149
>TIE1_HUMAN (P35590) Tyrosine-protein kinase receptor Tie-1 precursor (EC| 2.7.10.1) Length = 1138 Score = 55.8 bits (133), Expect = 1e-07 Identities = 30/80 (37%), Positives = 50/80 (62%), Gaps = 1/80 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFG+LLWE+++ G PY +T + + Q G R P+N ++ EL+++CW+ Sbjct: 1034 SDVWSFGVLLWEIVSLGGTPYCGMTCAELYEKLPQ-GYRMEQPRNCDDEVYELMRQCWRD 1092 Query: 463 DPAERPDFSEILEALKKIAE 404 P ERP F++I L ++ E Sbjct: 1093 RPYERPPFAQIALQLGRMLE 1112
>ROS_CHICK (P08941) Proto-oncogene tyrosine-protein kinase ROS precursor (EC| 2.7.10.1) (c-ros-1) Length = 2311 Score = 55.8 bits (133), Expect = 1e-07 Identities = 30/78 (38%), Positives = 47/78 (60%), Gaps = 1/78 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV++FG+L+WE LT G+ PY L+ ++ + V+ G R P N + +L+ +CW Q Sbjct: 2159 SDVWAFGVLVWETLTLGQQPYPGLSNIEV-LHHVRSGGRLESPNNCPDDIRDLMTRCWAQ 2217 Query: 463 DPAERPDFSEILEALKKI 410 DP RP F I L++I Sbjct: 2218 DPHNRPTFFYIQHKLQEI 2235
>ROS_AVISU (P00529) Tyrosine-protein kinase transforming protein ros (EC| 2.7.10.1) Length = 402 Score = 55.8 bits (133), Expect = 1e-07 Identities = 30/78 (38%), Positives = 47/78 (60%), Gaps = 1/78 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV++FG+L+WE LT G+ PY L+ ++ + V+ G R P N + +L+ +CW Q Sbjct: 296 SDVWAFGVLVWETLTLGQQPYPGLSNIEV-LHHVRSGGRLESPNNCPDDIRDLMTRCWAQ 354 Query: 463 DPAERPDFSEILEALKKI 410 DP RP F I L++I Sbjct: 355 DPHNRPTFFYIQHKLQEI 372
>TIE1_MOUSE (Q06806) Tyrosine-protein kinase receptor Tie-1 precursor (EC| 2.7.10.1) Length = 1134 Score = 55.8 bits (133), Expect = 1e-07 Identities = 30/80 (37%), Positives = 50/80 (62%), Gaps = 1/80 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFG+LLWE+++ G PY +T + + Q G R P+N ++ EL+++CW+ Sbjct: 1030 SDVWSFGVLLWEIVSLGGTPYCGMTCAELYEKLPQ-GYRMEQPRNCDDEVYELMRQCWRD 1088 Query: 463 DPAERPDFSEILEALKKIAE 404 P ERP F++I L ++ E Sbjct: 1089 RPYERPPFAQIALQLGRMLE 1108
>FES_FSVGA (P00542) Tyrosine-protein kinase transforming protein Fes (EC| 2.7.10.2) Length = 609 Score = 55.5 bits (132), Expect = 1e-07 Identities = 31/78 (39%), Positives = 45/78 (57%), Gaps = 1/78 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFGILLWE + G PY L+ Q V+KG R P+ + L+++CW Sbjct: 528 SDVWSFGILLWETFSLGASPYPNLSNQQTRE-FVEKGGRLPCPELCPDAVFRLMEQCWAY 586 Query: 463 DPAERPDFSEILEALKKI 410 +P +RP FS I + L+ I Sbjct: 587 EPGQRPSFSAIYQELQSI 604
>SEA_AVIET (P23049) Tyrosine-protein kinase transforming protein SEA (EC| 2.7.10.2) Length = 370 Score = 55.5 bits (132), Expect = 1e-07 Identities = 31/86 (36%), Positives = 48/86 (55%), Gaps = 1/86 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFG+L+WELLT G PY + P A ++ +G R P+ L ++ CW Sbjct: 246 SDVWSFGVLMWELLTRGASPYPEVDPYDMARYLL-RGRRLPQPQPCPDTLYGVMLSCWAP 304 Query: 463 DPAERPDFSEILEALKKIAEEVGDEH 386 P ERP FS ++ L+++ + EH Sbjct: 305 TPEERPSFSGLVCELERVLASLEGEH 330
>FGFR1_DROME (Q07407) Fibroblast growth factor receptor homolog 1 precursor (EC| 2.7.10.1) (Protein heartless) Length = 729 Score = 55.5 bits (132), Expect = 1e-07 Identities = 28/87 (32%), Positives = 48/87 (55%), Gaps = 1/87 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+S+GILLWE++T G+ PY + + + G R P + L+++CW Sbjct: 614 SDVWSYGILLWEIMTYGQQPYPTIMSAEELYTYLMSGQRMEKPAKCSMNIYILMRQCWHF 673 Query: 463 DPAERPDFSEILEALKKIAEEVGDEHD 383 + +RP F+EI+E + K+ + D D Sbjct: 674 NADDRPPFTEIVEYMDKLLQTKEDYLD 700
>FES_FELCA (P14238) Proto-oncogene tyrosine-protein kinase FES/FPS (EC| 2.7.10.2) (C-FES) Length = 820 Score = 55.5 bits (132), Expect = 1e-07 Identities = 31/78 (39%), Positives = 45/78 (57%), Gaps = 1/78 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFGILLWE + G PY L+ Q V+KG R P+ + L+++CW Sbjct: 739 SDVWSFGILLWETFSLGASPYPNLSNQQTRE-FVEKGGRLPCPELCPDAVFRLMEQCWAY 797 Query: 463 DPAERPDFSEILEALKKI 410 +P +RP FS I + L+ I Sbjct: 798 EPGQRPSFSAIYQELQSI 815
>PGFRA_HUMAN (P16234) Alpha platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-alpha) (CD140a antigen) Length = 1089 Score = 55.5 bits (132), Expect = 1e-07 Identities = 29/78 (37%), Positives = 46/78 (58%), Gaps = 4/78 (5%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+S+GILLWE+ + G PY + ++ G R P +A +++ E++ KCW Sbjct: 876 SDVWSYGILLWEIFSLGGTPYPGMMVDSTFYNKIKSGYRMAKPDHATSEVYEIMVKCWNS 935 Query: 463 DPAERPDF---SEILEAL 419 +P +RP F SEI+E L Sbjct: 936 EPEKRPSFYHLSEIVENL 953
>VGFR3_MOUSE (P35917) Vascular endothelial growth factor receptor 3 precursor (EC| 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4) Length = 1363 Score = 55.5 bits (132), Expect = 1e-07 Identities = 28/91 (30%), Positives = 50/91 (54%), Gaps = 1/91 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFG+LLWE+ + G PY + + ++ G R P+ A + ++Q CW Sbjct: 1095 SDVWSFGVLLWEIFSLGASPYPGVQINEEFCQRLKDGTRMRAPELATPAIRHIMQSCWSG 1154 Query: 463 DPAERPDFSEILEALKKIAEEVGDEHDGKHK 371 DP RP FS+++E L + + G + + + + Sbjct: 1155 DPKARPAFSDLVEILGDLLQGGGWQEEEEER 1185
>KIT_CHICK (Q08156) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 960 Score = 55.5 bits (132), Expect = 1e-07 Identities = 24/77 (31%), Positives = 48/77 (62%), Gaps = 1/77 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+S+GILLWEL + G PY + ++++G R P+ + ++ ++++ CW Sbjct: 835 SDVWSYGILLWELFSLGSSPYPGMPVDSKFYKMIKEGYRMFSPECSPPEMYDIMKSCWDA 894 Query: 463 DPAERPDFSEILEALKK 413 DP +RP F +I++ +++ Sbjct: 895 DPLQRPTFKQIVQLIEQ 911
>FES_HUMAN (P07332) Proto-oncogene tyrosine-protein kinase Fes/Fps (EC| 2.7.10.2) (C-Fes) Length = 822 Score = 55.5 bits (132), Expect = 1e-07 Identities = 31/78 (39%), Positives = 45/78 (57%), Gaps = 1/78 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFGILLWE + G PY L+ Q V+KG R P+ + L+++CW Sbjct: 741 SDVWSFGILLWETFSLGASPYPNLSNQQTRE-FVEKGGRLPCPELCPDAVFRLMEQCWAY 799 Query: 463 DPAERPDFSEILEALKKI 410 +P +RP FS I + L+ I Sbjct: 800 EPGQRPSFSTIYQELQSI 817
>ALK_HUMAN (Q9UM73) ALK tyrosine kinase receptor precursor (EC 2.7.10.1)| (Anaplastic lymphoma kinase) (CD246 antigen) Length = 1620 Score = 55.5 bits (132), Expect = 1e-07 Identities = 28/80 (35%), Positives = 46/80 (57%), Gaps = 1/80 (1%) Frame = -2 Query: 637 DVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQD 461 D +SFG+LLWE+ + G +PY + Q + V G R PKN + ++ +CWQ Sbjct: 1311 DTWSFGVLLWEIFSLGYMPYPSKSN-QEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQ 1369 Query: 460 PAERPDFSEILEALKKIAEE 401 P +RP+F+ ILE ++ ++ Sbjct: 1370 PEDRPNFAIILERIEYCTQD 1389
>ALK_MOUSE (P97793) ALK tyrosine kinase receptor precursor (EC 2.7.10.1)| (Anaplastic lymphoma kinase) (CD246 antigen) Length = 1621 Score = 55.5 bits (132), Expect = 1e-07 Identities = 28/80 (35%), Positives = 46/80 (57%), Gaps = 1/80 (1%) Frame = -2 Query: 637 DVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQD 461 D +SFG+LLWE+ + G +PY + Q + V G R PKN + ++ +CWQ Sbjct: 1315 DTWSFGVLLWEIFSLGYMPYPSKSN-QEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQ 1373 Query: 460 PAERPDFSEILEALKKIAEE 401 P +RP+F+ ILE ++ ++ Sbjct: 1374 PEDRPNFAIILERIEYCTQD 1393
>FGFR2_XENLA (Q03364) Fibroblast growth factor receptor 2 precursor (EC| 2.7.10.1) (FGFR-2) Length = 813 Score = 55.5 bits (132), Expect = 1e-07 Identities = 27/78 (34%), Positives = 48/78 (61%), Gaps = 1/78 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFG+L+WE+ T G PY + P++ ++++G R P N +L +++ CW Sbjct: 674 SDVWSFGVLMWEIFTLGGSPYPGI-PVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHA 732 Query: 463 DPAERPDFSEILEALKKI 410 P+ RP F +++E L +I Sbjct: 733 IPSHRPTFKQLVEDLDRI 750
>FYN_MOUSE (P39688) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 533 Score = 55.5 bits (132), Expect = 1e-07 Identities = 29/68 (42%), Positives = 44/68 (64%), Gaps = 1/68 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFGILL EL+T G++PY + + + V++G R P++ L EL+ CW++ Sbjct: 443 SDVWSFGILLTELVTKGRVPYPGMNNREV-LEQVERGYRMPCPQDCPISLHELMIHCWKK 501 Query: 463 DPAERPDF 440 DP ERP F Sbjct: 502 DPEERPTF 509
>FYN_CHICK (Q05876) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 533 Score = 55.5 bits (132), Expect = 1e-07 Identities = 29/68 (42%), Positives = 44/68 (64%), Gaps = 1/68 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFGILL EL+T G++PY + + + V++G R P++ L EL+ CW++ Sbjct: 443 SDVWSFGILLTELVTKGRVPYPGMNNREV-LEQVERGYRMPCPQDCPISLHELMIHCWKK 501 Query: 463 DPAERPDF 440 DP ERP F Sbjct: 502 DPEERPTF 509
>ANPRB_HUMAN (P20594) Atrial natriuretic peptide receptor B precursor (ANP-B)| (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor) Length = 1047 Score = 55.5 bits (132), Expect = 1e-07 Identities = 36/91 (39%), Positives = 51/91 (56%), Gaps = 9/91 (9%) Frame = -2 Query: 640 ADVFSFGILLWELLTGKIPYEYLTPLQAA----VGVVQKGLRPTI-PKNAHAKLTE---- 488 ADV+SFGI+L E+ P+ YL L + V V+ G RP P +L E Sbjct: 705 ADVYSFGIILQEIALRSGPF-YLEGLDLSPKEIVQKVRNGQRPYFRPSIDRTQLNEELVL 763 Query: 487 LLQKCWQQDPAERPDFSEILEALKKIAEEVG 395 L+++CW QDPAERPDF +I +++ +E G Sbjct: 764 LMERCWAQDPAERPDFGQIKGFIRRFNKEGG 794
>ANPRB_BOVIN (P46197) Atrial natriuretic peptide receptor B precursor (ANP-B)| (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor) Length = 1047 Score = 55.5 bits (132), Expect = 1e-07 Identities = 36/91 (39%), Positives = 51/91 (56%), Gaps = 9/91 (9%) Frame = -2 Query: 640 ADVFSFGILLWELLTGKIPYEYLTPLQAA----VGVVQKGLRPTI-PKNAHAKLTE---- 488 ADV+SFGI+L E+ P+ YL L + V V+ G RP P +L E Sbjct: 705 ADVYSFGIILQEIALRSGPF-YLEGLDLSPKEIVQKVRNGQRPYFRPSIDRTQLNEELVL 763 Query: 487 LLQKCWQQDPAERPDFSEILEALKKIAEEVG 395 L+++CW QDPAERPDF +I +++ +E G Sbjct: 764 LMERCWAQDPAERPDFGQIKGFIRRFNKEGG 794
>BTK_MOUSE (P35991) Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton's| tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB) Length = 658 Score = 55.5 bits (132), Expect = 1e-07 Identities = 27/81 (33%), Positives = 47/81 (58%), Gaps = 1/81 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +D+++FG+L+WE+ + GK+PYE T + A + Q GLR P A ++ ++ CW + Sbjct: 577 SDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQ-GLRLYRPHLASERVYTIMYSCWHE 635 Query: 463 DPAERPDFSEILEALKKIAEE 401 ERP F +L + + +E Sbjct: 636 KADERPSFKILLSNILDVMDE 656
>INSR_XENLA (Q9PVZ4) Insulin receptor precursor (EC 2.7.10.1) (IR) (Xe-InsR)| (XTK-1b) [Contains: Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1362 Score = 55.5 bits (132), Expect = 1e-07 Identities = 30/76 (39%), Positives = 46/76 (60%), Gaps = 1/76 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFG++LWE+ + + PY+ L+ Q V+ G P+N +L L+Q CWQ Sbjct: 1206 SDVWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGSLDH-PENCPPRLHSLMQMCWQY 1264 Query: 463 DPAERPDFSEILEALK 416 +P RP F EI++ LK Sbjct: 1265 NPKMRPTFLEIIDMLK 1280
>FGFR3_MOUSE (Q61851) Fibroblast growth factor receptor 3 precursor (EC| 2.7.10.1) (FGFR-3) (Heparin-binding growth factor receptor) Length = 801 Score = 55.1 bits (131), Expect = 2e-07 Identities = 27/79 (34%), Positives = 49/79 (62%), Gaps = 2/79 (2%) Frame = -2 Query: 640 ADVFSFGILLWELLT--GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQ 467 +DV+SFG+LLWE+ T G PY + P++ ++++G R P + L ++++CW Sbjct: 669 SDVWSFGVLLWEIFTPGGPSPYPGI-PVEELFKLLKEGHRMDKPASCTHDLYMIMRECWH 727 Query: 466 QDPAERPDFSEILEALKKI 410 P++RP F +++E L +I Sbjct: 728 AVPSQRPTFKQLVEDLDRI 746
>EPHA7_CHICK (O42422) Ephrin type-A receptor 7 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor CEPHA7) (Tyrosine-protein kinase receptor CEK11) Length = 993 Score = 55.1 bits (131), Expect = 2e-07 Identities = 27/78 (34%), Positives = 50/78 (64%), Gaps = 1/78 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+S+GI++WE+++ G+ PY ++ Q + +++G R P + A L +L+ CWQ+ Sbjct: 812 SDVWSYGIVMWEVMSYGERPYWDMSN-QDVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQK 870 Query: 463 DPAERPDFSEILEALKKI 410 + ERP F +I+ L K+ Sbjct: 871 ERGERPKFEQIVGILDKM 888
>HCK_MACFA (Q95M30) Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK)| (Hemopoietic cell kinase) Length = 503 Score = 55.1 bits (131), Expect = 2e-07 Identities = 28/75 (37%), Positives = 46/75 (61%), Gaps = 1/75 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFGILL E++T G+IPY ++ + + +++G R P+N +L ++ +CW+ Sbjct: 415 SDVWSFGILLMEIVTYGRIPYPGMSNPEV-IRALERGYRMPRPENCPEELYNIMMRCWKN 473 Query: 463 DPAERPDFSEILEAL 419 P ERP F I L Sbjct: 474 RPEERPTFEYIQSVL 488
>VGFR3_RAT (Q91ZT1) Vascular endothelial growth factor receptor 3 precursor (EC| 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4) Length = 1363 Score = 55.1 bits (131), Expect = 2e-07 Identities = 28/83 (33%), Positives = 46/83 (55%), Gaps = 1/83 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFG+LLWE+ + G PY + + ++ G R P+ A + ++Q CW Sbjct: 1095 SDVWSFGVLLWEIFSLGASPYPGVQINEEFCQRLKDGTRMRAPELATPAIRHIMQSCWSG 1154 Query: 463 DPAERPDFSEILEALKKIAEEVG 395 DP RP FS+++E L + + G Sbjct: 1155 DPKARPAFSDLVEILGDLLQGGG 1177
>YES_XENLA (P10936) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 536 Score = 55.1 bits (131), Expect = 2e-07 Identities = 30/76 (39%), Positives = 46/76 (60%), Gaps = 1/76 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFGILL EL+ G++PY + + + V++G R P+ L EL++ CW++ Sbjct: 446 SDVWSFGILLTELVAKGRVPYPGMVNREV-LEQVERGYRMPCPQRCPESLHELMKLCWKK 504 Query: 463 DPAERPDFSEILEALK 416 DP ERP F I L+ Sbjct: 505 DPDERPTFEYIQSFLE 520
>EPHA8_HUMAN (P29322) Ephrin type-A receptor 8 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase) (HEK3) Length = 1005 Score = 55.1 bits (131), Expect = 2e-07 Identities = 28/75 (37%), Positives = 46/75 (61%), Gaps = 1/75 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFG+++WE+L G+ PY +T + + V++G R P L +L+ CW + Sbjct: 819 SDVWSFGVVMWEVLAYGERPYWNMTN-RDVISSVEEGYRLPAPMGCPHALHQLMLDCWHK 877 Query: 463 DPAERPDFSEILEAL 419 D A+RP FS+I+ L Sbjct: 878 DRAQRPRFSQIVSVL 892
>YES_XIPHE (P27447) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 543 Score = 55.1 bits (131), Expect = 2e-07 Identities = 29/76 (38%), Positives = 47/76 (61%), Gaps = 1/76 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFGILL EL+T G++PY + + + V +G R P+ L E++++CW++ Sbjct: 453 SDVWSFGILLTELVTKGRVPYPGMVNREV-LEQVDRGYRMPCPQGCPESLHEMMRQCWKK 511 Query: 463 DPAERPDFSEILEALK 416 +P ERP F I L+ Sbjct: 512 EPDERPTFEYIQSFLE 527
>INSRR_HUMAN (P14616) Insulin receptor-related protein precursor (EC 2.7.10.1)| (IRR) (IR-related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain] Length = 1297 Score = 55.1 bits (131), Expect = 2e-07 Identities = 27/77 (35%), Positives = 50/77 (64%), Gaps = 1/77 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFG++LWE++T + PY+ L+ Q V+ G+ + + +L EL+ +CWQ Sbjct: 1173 SDVWSFGVVLWEIVTLAEQPYQGLSNEQVLKFVMDGGVLEEL-EGCPLQLQELMSRCWQP 1231 Query: 463 DPAERPDFSEILEALKK 413 +P RP F+ IL+++++ Sbjct: 1232 NPRLRPSFTHILDSIQE 1248
>BMX_MOUSE (P97504) Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2)| (Bone marrow tyrosine kinase gene in chromosome X protein homolog) Length = 651 Score = 55.1 bits (131), Expect = 2e-07 Identities = 28/81 (34%), Positives = 49/81 (60%), Gaps = 1/81 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV++FGIL+WE+ + GK PY+ + V V Q G R P+ A + +++ CW + Sbjct: 569 SDVWAFGILMWEVFSLGKQPYDLYDNSEVVVKVSQ-GHRLYRPQLASDTIYQIMYSCWHE 627 Query: 463 DPAERPDFSEILEALKKIAEE 401 P +RP F ++L A++ + E+ Sbjct: 628 LPEKRPTFQQLLSAIEPLREQ 648
>HCK_HUMAN (P08631) Tyrosine-protein kinase HCK (EC 2.7.10.2)| (p59-HCK/p60-HCK) (Hemopoietic cell kinase) Length = 525 Score = 55.1 bits (131), Expect = 2e-07 Identities = 28/75 (37%), Positives = 46/75 (61%), Gaps = 1/75 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFGILL E++T G+IPY ++ + + +++G R P+N +L ++ +CW+ Sbjct: 437 SDVWSFGILLMEIVTYGRIPYPGMSNPEV-IRALERGYRMPRPENCPEELYNIMMRCWKN 495 Query: 463 DPAERPDFSEILEAL 419 P ERP F I L Sbjct: 496 RPEERPTFEYIQSVL 510
>EPHA3_MOUSE (P29319) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ETK1) (MEK4) Length = 983 Score = 55.1 bits (131), Expect = 2e-07 Identities = 29/83 (34%), Positives = 48/83 (57%), Gaps = 1/83 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+S+GI+LWE+++ G+ PY ++ Q + V + R P + A L +L+ CWQ+ Sbjct: 805 SDVWSYGIVLWEVMSYGERPYSQMSN-QDVIKAVDERYRLPPPMDCPAALYQLMLDCWQK 863 Query: 463 DPAERPDFSEILEALKKIAEEVG 395 D RP F +I+ L K+ G Sbjct: 864 DRNNRPKFEQIVSILDKLIRNPG 886
>LTK_MOUSE (P08923) Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1)| Length = 888 Score = 55.1 bits (131), Expect = 2e-07 Identities = 28/80 (35%), Positives = 44/80 (55%), Gaps = 1/80 (1%) Frame = -2 Query: 637 DVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQD 461 D +SFG+LLWE+ + G +PY T Q + + G R P+N + ++ +CWQ Sbjct: 701 DSWSFGVLLWEIFSLGYMPYPGHTN-QEVLDFIATGNRMDPPRNCPGPVYRIMTQCWQHQ 759 Query: 460 PAERPDFSEILEALKKIAEE 401 P RPDF ILE ++ ++ Sbjct: 760 PELRPDFGSILERIQYCTQD 779
>INSR_RAT (P15127) Insulin receptor precursor (EC 2.7.10.1) (IR) [Contains:| Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1383 Score = 54.7 bits (130), Expect = 2e-07 Identities = 31/77 (40%), Positives = 48/77 (62%), Gaps = 2/77 (2%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKG-LRPTIPKNAHAKLTELLQKCWQ 467 +D++SFG++LWE+ + + PY+ L+ Q V+ G L P P N +LT+L++ CWQ Sbjct: 1218 SDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDP--PDNCPERLTDLMRMCWQ 1275 Query: 466 QDPAERPDFSEILEALK 416 +P RP F EI+ LK Sbjct: 1276 FNPKMRPTFLEIVNLLK 1292
>LCK_HUMAN (P06239) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell-specific protein-tyrosine kinase) Length = 508 Score = 54.7 bits (130), Expect = 2e-07 Identities = 30/91 (32%), Positives = 56/91 (61%), Gaps = 1/91 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFGILL E++T G+IPY +T + + +++G R P N +L +L++ CW++ Sbjct: 420 SDVWSFGILLTEIVTHGRIPYPGMTNPEV-IQNLERGYRMVRPDNCPEELYQLMRLCWKE 478 Query: 463 DPAERPDFSEILEALKKIAEEVGDEHDGKHK 371 P +RP F + L+ + E+ +G+++ Sbjct: 479 RPEDRPTF----DYLRSVLEDFFTATEGQYQ 505
>SRC2_XENLA (P13116) Tyrosine-protein kinase Src-2 (EC 2.7.10.2) (p60-Src-2)| Length = 531 Score = 54.7 bits (130), Expect = 2e-07 Identities = 31/74 (41%), Positives = 47/74 (63%), Gaps = 1/74 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFGILL EL T G++PY + + + V++G R P + L +L+ +CW++ Sbjct: 441 SDVWSFGILLTELTTKGRVPYPGMVNREV-LDQVERGYRMPCPPDCPESLHDLMFQCWRK 499 Query: 463 DPAERPDFSEILEA 422 DP ERP F E L+A Sbjct: 500 DPEERPTF-EYLQA 512
>SRC1_XENLA (P13115) Tyrosine-protein kinase Src-1 (EC 2.7.10.2) (p60-Src-1)| Length = 531 Score = 54.7 bits (130), Expect = 2e-07 Identities = 31/74 (41%), Positives = 47/74 (63%), Gaps = 1/74 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFGILL EL T G++PY + + + V++G R P + L +L+ +CW++ Sbjct: 441 SDVWSFGILLTELTTKGRVPYPGMVNREV-LDQVERGYRMPCPPDCPESLHDLMFQCWRK 499 Query: 463 DPAERPDFSEILEA 422 DP ERP F E L+A Sbjct: 500 DPEERPTF-EYLQA 512
>ABL_DROME (P00522) Tyrosine-protein kinase Abl (EC 2.7.10.2) (Abelson| protein) (D-ash) Length = 1620 Score = 54.7 bits (130), Expect = 2e-07 Identities = 29/81 (35%), Positives = 46/81 (56%), Gaps = 1/81 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV++FG+LLWE+ T G PY + L + KG R P ++ +L+++CWQ Sbjct: 549 SDVWAFGVLLWEIATYGMSPYPAID-LTDVYHKLDKGYRMERPPGCPPEVYDLMRQCWQW 607 Query: 463 DPAERPDFSEILEALKKIAEE 401 D +RP F I AL+ + +E Sbjct: 608 DATDRPTFKSIHHALEHMFQE 628
>EPHA8_MOUSE (O09127) Ephrin type-A receptor 8 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase) Length = 1004 Score = 54.7 bits (130), Expect = 2e-07 Identities = 27/75 (36%), Positives = 45/75 (60%), Gaps = 1/75 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFG+++WE+L G+ PY +T Q + V++G R P L +L+ CW + Sbjct: 818 SDVWSFGVVMWEVLAYGERPYWNMTN-QDVISSVEEGYRLPAPMGCPRALHQLMLDCWHK 876 Query: 463 DPAERPDFSEILEAL 419 D A+RP F+ ++ L Sbjct: 877 DRAQRPRFAHVVSVL 891
>EPA4B_XENLA (Q91694) Ephrin type-A receptor 4-B precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor PAG) (Pagliaccio) Length = 985 Score = 54.7 bits (130), Expect = 2e-07 Identities = 26/78 (33%), Positives = 50/78 (64%), Gaps = 1/78 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+S+GI++WE+++ G+ PY ++ Q + +++G R P + L +L+ CWQ+ Sbjct: 804 SDVWSYGIVMWEVMSYGERPYWDMSN-QDVIKAIEEGYRLPPPMDCPIALHQLMLDCWQK 862 Query: 463 DPAERPDFSEILEALKKI 410 D ++RP F +I+ L K+ Sbjct: 863 DRSDRPKFGQIVSMLDKL 880
>INSR_MOUSE (P15208) Insulin receptor precursor (EC 2.7.10.1) (IR) [Contains:| Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1372 Score = 54.7 bits (130), Expect = 2e-07 Identities = 31/77 (40%), Positives = 48/77 (62%), Gaps = 2/77 (2%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKG-LRPTIPKNAHAKLTELLQKCWQ 467 +D++SFG++LWE+ + + PY+ L+ Q V+ G L P P N +LT+L++ CWQ Sbjct: 1207 SDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDP--PDNCPERLTDLMRMCWQ 1264 Query: 466 QDPAERPDFSEILEALK 416 +P RP F EI+ LK Sbjct: 1265 FNPKMRPTFLEIVNLLK 1281
>FAK2_RAT (P70600) Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal| adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) Length = 1009 Score = 54.7 bits (130), Expect = 2e-07 Identities = 28/78 (35%), Positives = 49/78 (62%), Gaps = 1/78 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+ F + +WE+L+ GK P+ +L + +GV++KG R P+ L L+ +CW Sbjct: 606 SDVWMFAVCMWEILSFGKQPFFWLEN-KDVIGVLEKGDRLPKPELCPPVLYTLMTRCWDY 664 Query: 463 DPAERPDFSEILEALKKI 410 DP++RP F+E++ +L I Sbjct: 665 DPSDRPRFTELVCSLSDI 682
>FAK2_MOUSE (Q9QVP9) Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal| adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinas Length = 1009 Score = 54.7 bits (130), Expect = 2e-07 Identities = 28/78 (35%), Positives = 49/78 (62%), Gaps = 1/78 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+ F + +WE+L+ GK P+ +L + +GV++KG R P+ L L+ +CW Sbjct: 606 SDVWMFAVCMWEILSFGKQPFFWLEN-KDVIGVLEKGDRLPKPELCPPVLYTLMTRCWDY 664 Query: 463 DPAERPDFSEILEALKKI 410 DP++RP F+E++ +L I Sbjct: 665 DPSDRPRFTELVCSLSDI 682
>EPHA3_CHICK (P29318) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ETK1) (CEK4) Length = 983 Score = 54.7 bits (130), Expect = 2e-07 Identities = 28/78 (35%), Positives = 47/78 (60%), Gaps = 1/78 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +D +S+GI+LWE+++ G+ PY ++ Q + V +G R P + A L +L+ CWQ+ Sbjct: 805 SDAWSYGIVLWEVMSYGERPYWEMS-FQDVIKAVDEGYRLPPPMDCPAALYQLMLDCWQK 863 Query: 463 DPAERPDFSEILEALKKI 410 D RP F +I+ L K+ Sbjct: 864 DRNNRPKFEQIVSILDKL 881
>SRK4_SPOLA (P42690) Tyrosine-protein kinase isoform SRK4 (EC 2.7.10.2)| Length = 506 Score = 54.7 bits (130), Expect = 2e-07 Identities = 33/92 (35%), Positives = 52/92 (56%), Gaps = 1/92 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFGI+L+E++T G+ PY +T Q + +Q+ R P KL ++ CW++ Sbjct: 416 SDVWSFGIVLYEVITYGRFPYPGMTNAQV-LEQIQQSYRMPRPMGCPEKLYAIMMDCWRE 474 Query: 463 DPAERPDFSEILEALKKIAEEVGDEHDGKHKD 368 DPA RP F + L++ GD D +KD Sbjct: 475 DPASRPTFETLSWQLEEFF-TTGD--DAGYKD 503
>SRC_AVIST (P14085) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 556 Score = 54.3 bits (129), Expect = 3e-07 Identities = 31/74 (41%), Positives = 46/74 (62%), Gaps = 1/74 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFGILL EL T G++PY + + + V++G R P L +L+ +CW++ Sbjct: 442 SDVWSFGILLTELTTKGRVPYPGMVNREV-LDQVERGYRMPCPPECPESLHDLMCQCWRK 500 Query: 463 DPAERPDFSEILEA 422 DP ERP F E L+A Sbjct: 501 DPEERPTF-EYLQA 513
>CSK_MOUSE (P41241) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| (Protein-tyrosine kinase MPK-2) (p50CSK) Length = 450 Score = 54.3 bits (129), Expect = 3e-07 Identities = 29/78 (37%), Positives = 47/78 (60%), Gaps = 1/78 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFGILLWE+ + G++PY + PL+ V V+KG + P + ++++ C Sbjct: 367 SDVWSFGILLWEIYSFGRVPYPRI-PLKDVVPRVEKGYKMDAPDGCPPAVYDVMKNCSHL 425 Query: 463 DPAERPDFSEILEALKKI 410 D A RP F ++ E L+ I Sbjct: 426 DAATRPTFLQLREQLEHI 443
>YES_HUMAN (P07947) Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2)| (p61-Yes) (c-Yes) Length = 542 Score = 54.3 bits (129), Expect = 3e-07 Identities = 30/76 (39%), Positives = 45/76 (59%), Gaps = 1/76 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFGIL EL+T G++PY + + + V++G R P+ L EL+ CW++ Sbjct: 452 SDVWSFGILQTELVTKGRVPYPGMVNREV-LEQVERGYRMPCPQGCPESLHELMNLCWKK 510 Query: 463 DPAERPDFSEILEALK 416 DP ERP F I L+ Sbjct: 511 DPDERPTFEYIQSFLE 526
>YES_MOUSE (Q04736) Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2)| (p61-Yes) (c-Yes) Length = 540 Score = 54.3 bits (129), Expect = 3e-07 Identities = 30/76 (39%), Positives = 45/76 (59%), Gaps = 1/76 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFGIL EL+T G++PY + + + V++G R P+ L EL+ CW++ Sbjct: 450 SDVWSFGILQTELVTKGRVPYPGMVNREV-LEQVERGYRMPCPQGCPESLHELMNLCWKK 508 Query: 463 DPAERPDFSEILEALK 416 DP ERP F I L+ Sbjct: 509 DPDERPTFEYIQSFLE 524
>MET_CALMO (Q2QLC0) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1381 Score = 54.3 bits (129), Expect = 3e-07 Identities = 32/86 (37%), Positives = 45/86 (52%), Gaps = 1/86 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFG+LLWEL+T G PY + V ++Q G R P+ L E++ KCW Sbjct: 1264 SDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQ-GRRLLQPEYCPDPLYEVMLKCWHP 1322 Query: 463 DPAERPDFSEILEALKKIAEEVGDEH 386 RP FSE++ + I EH Sbjct: 1323 KAEMRPSFSELVSRISAIFSTFIGEH 1348
>MET_CALJA (Q2QLG5) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1381 Score = 54.3 bits (129), Expect = 3e-07 Identities = 32/86 (37%), Positives = 45/86 (52%), Gaps = 1/86 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFG+LLWEL+T G PY + V ++Q G R P+ L E++ KCW Sbjct: 1264 SDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQ-GRRLLQPEYCPDPLYEVMLKCWHP 1322 Query: 463 DPAERPDFSEILEALKKIAEEVGDEH 386 RP FSE++ + I EH Sbjct: 1323 KAEMRPSFSELVSRISAIFSTFIGEH 1348
>SRC_AVIS2 (P15054) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 586 Score = 54.3 bits (129), Expect = 3e-07 Identities = 31/74 (41%), Positives = 46/74 (62%), Gaps = 1/74 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFGILL EL T G++PY + + + V++G R P L +L+ +CW++ Sbjct: 442 SDVWSFGILLTELTTKGRVPYPGMVNREV-LDQVERGYRMPCPPECPESLHDLMCQCWRK 500 Query: 463 DPAERPDFSEILEA 422 DP ERP F E L+A Sbjct: 501 DPEERPTF-EYLQA 513
>MET_PONPY (Q2IBD8) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1390 Score = 54.3 bits (129), Expect = 3e-07 Identities = 32/86 (37%), Positives = 45/86 (52%), Gaps = 1/86 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFG+LLWEL+T G PY + V ++Q G R P+ L E++ KCW Sbjct: 1264 SDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQ-GRRLLQPEYCPDPLYEVMLKCWHP 1322 Query: 463 DPAERPDFSEILEALKKIAEEVGDEH 386 RP FSE++ + I EH Sbjct: 1323 KAEMRPSFSELVSRISAIFSTFIGEH 1348
>MET_PANTR (Q2QLF1) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1390 Score = 54.3 bits (129), Expect = 3e-07 Identities = 32/86 (37%), Positives = 45/86 (52%), Gaps = 1/86 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFG+LLWEL+T G PY + V ++Q G R P+ L E++ KCW Sbjct: 1264 SDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQ-GRRLLQPEYCPDPLYEVMLKCWHP 1322 Query: 463 DPAERPDFSEILEALKKIAEEVGDEH 386 RP FSE++ + I EH Sbjct: 1323 KAEMRPSFSELVSRISAIFSTFIGEH 1348
>SRC_CHICK (P00523) Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2)| (p60-Src) (c-Src) (pp60c-src) Length = 532 Score = 54.3 bits (129), Expect = 3e-07 Identities = 31/74 (41%), Positives = 46/74 (62%), Gaps = 1/74 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFGILL EL T G++PY + + + V++G R P L +L+ +CW++ Sbjct: 442 SDVWSFGILLTELTTKGRVPYPGMVNREV-LDQVERGYRMPCPPECPESLHDLMCQCWRK 500 Query: 463 DPAERPDFSEILEA 422 DP ERP F E L+A Sbjct: 501 DPEERPTF-EYLQA 513
>MET_OTOGA (Q2QLH6) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1382 Score = 54.3 bits (129), Expect = 3e-07 Identities = 32/86 (37%), Positives = 45/86 (52%), Gaps = 1/86 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFG+LLWEL+T G PY + V ++Q G R P+ L E++ KCW Sbjct: 1265 SDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQ-GRRLLQPEYCPDPLYEVMLKCWHP 1323 Query: 463 DPAERPDFSEILEALKKIAEEVGDEH 386 RP FSE++ + I EH Sbjct: 1324 KAEMRPSFSELVSRISAIFSTFIGEH 1349
>MET_MICMU (Q2QL89) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1382 Score = 54.3 bits (129), Expect = 3e-07 Identities = 32/86 (37%), Positives = 45/86 (52%), Gaps = 1/86 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFG+LLWEL+T G PY + V ++Q G R P+ L E++ KCW Sbjct: 1265 SDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQ-GRRLLQPEYCPDPLYEVMLKCWHP 1323 Query: 463 DPAERPDFSEILEALKKIAEEVGDEH 386 RP FSE++ + I EH Sbjct: 1324 KAEMRPSFSELVSRISAIFSTFIGEH 1349
>SRC_AVISS (P14084) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 567 Score = 54.3 bits (129), Expect = 3e-07 Identities = 31/74 (41%), Positives = 46/74 (62%), Gaps = 1/74 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFGILL EL T G++PY + + + V++G R P L +L+ +CW++ Sbjct: 442 SDVWSFGILLTELTTKGRVPYPGMVNREV-LDQVERGYRMPCPPECPESLHDLMCQCWRK 500 Query: 463 DPAERPDFSEILEA 422 DP ERP F E L+A Sbjct: 501 DPEERPTF-EYLQA 513
>PGFRA_XENLA (P26619) Alpha platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-alpha) Length = 1087 Score = 54.3 bits (129), Expect = 3e-07 Identities = 28/78 (35%), Positives = 46/78 (58%), Gaps = 4/78 (5%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFGILLWE+ + G PY + ++ G R P +A ++ +++ KCW Sbjct: 876 SDVWSFGILLWEIFSLGGTPYPGMIVDSTFYNKIKSGYRMAKPDHATHEVYDIMVKCWNS 935 Query: 463 DPAERPDF---SEILEAL 419 +P +RP F S+I+E+L Sbjct: 936 EPEKRPSFRHLSDIVESL 953
>MET_MOUSE (P16056) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1379 Score = 54.3 bits (129), Expect = 3e-07 Identities = 31/86 (36%), Positives = 45/86 (52%), Gaps = 1/86 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFG+LLWEL+T G PY + + ++Q G R P+ L E++ KCW Sbjct: 1262 SDVWSFGVLLWELMTRGAPPYPDVNTFDITIYLLQ-GRRLLQPEYCPDALYEVMLKCWHP 1320 Query: 463 DPAERPDFSEILEALKKIAEEVGDEH 386 RP FSE++ + I EH Sbjct: 1321 KAEMRPSFSELVSRISSIFSTFIGEH 1346
>VGFR2_HUMAN (P35968) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Kinase insert domain receptor) (Protein-tyrosine kinase receptor Flk-1) (CD309 antigen) Length = 1356 Score = 53.9 bits (128), Expect = 4e-07 Identities = 28/89 (31%), Positives = 50/89 (56%), Gaps = 1/89 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFG+LLWE+ + G PY + + +++G R P ++ + + CW Sbjct: 1086 SDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHG 1145 Query: 463 DPAERPDFSEILEALKKIAEEVGDEHDGK 377 +P++RP FSE++E L + + + DGK Sbjct: 1146 EPSQRPTFSELVEHLGNLL-QANAQQDGK 1173
>FGFR2_DROME (Q09147) Fibroblast growth factor receptor homolog 2 precursor (EC| 2.7.10.1) (Protein breathless) (dFGF-R1) Length = 1052 Score = 53.9 bits (128), Expect = 4e-07 Identities = 25/94 (26%), Positives = 49/94 (52%), Gaps = 1/94 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+S+G+LLWE++T G PY ++ + + G R P + ++++CW Sbjct: 922 SDVWSYGVLLWEIMTYGDQPYPHILSAEELYSYLITGQRMEKPAKCSLNIYVVMRQCWHF 981 Query: 463 DPAERPDFSEILEALKKIAEEVGDEHDGKHKDKS 362 + RP F+E++E+ I ++ + + D S Sbjct: 982 ESCARPTFAELVESFDGILQQASSNPNDAYLDLS 1015
>CSF1R_FELCA (P13369) Macrophage colony-stimulating factor 1 receptor precursor| (CSF-1-R) (EC 2.7.10.1) (Fms proto-oncogene) (c-fms) Length = 980 Score = 53.9 bits (128), Expect = 4e-07 Identities = 28/81 (34%), Positives = 44/81 (54%), Gaps = 1/81 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+S+GILLWE+ + G PY + +V+ G + P A + ++Q CW Sbjct: 834 SDVWSYGILLWEIFSLGLNPYPGILVNSKFYKLVKDGYQMAQPAFAPKNIYSIMQACWAL 893 Query: 463 DPAERPDFSEILEALKKIAEE 401 +P RP F +I L+K A+E Sbjct: 894 EPTRRPTFQQICSLLQKQAQE 914
>PGFRA_MOUSE (P26618) Alpha platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-alpha) Length = 1089 Score = 53.9 bits (128), Expect = 4e-07 Identities = 28/78 (35%), Positives = 46/78 (58%), Gaps = 4/78 (5%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+S+GILLWE+ + G PY + ++ G R P +A +++ E++ +CW Sbjct: 876 SDVWSYGILLWEIFSLGGTPYPGMMVDSTFYNKIKSGYRMAKPDHATSEVYEIMVQCWNS 935 Query: 463 DPAERPDF---SEILEAL 419 +P +RP F SEI+E L Sbjct: 936 EPEKRPSFYHLSEIVENL 953
>MET_HORSE (Q2QLA9) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1381 Score = 53.9 bits (128), Expect = 4e-07 Identities = 32/86 (37%), Positives = 45/86 (52%), Gaps = 1/86 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFG+LLWEL+T G PY + V ++Q G R P+ L E++ KCW Sbjct: 1264 SDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQ-GRRLLQPEYCPDPLYEVMLKCWHP 1322 Query: 463 DPAERPDFSEILEALKKIAEEVGDEH 386 RP FSE++ + I EH Sbjct: 1323 KAELRPSFSELVSRISAIFSTFIGEH 1348
>7LESS_DROVI (P20806) Protein sevenless (EC 2.7.10.1)| Length = 2594 Score = 53.9 bits (128), Expect = 4e-07 Identities = 28/82 (34%), Positives = 47/82 (57%), Gaps = 1/82 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV++FG+L WE+ T G+ PY + + V++G R P+ KL LL +CW+ Sbjct: 2419 SDVWAFGVLCWEIFTLGQQPYAARNNFEV-LAHVKEGGRLQQPERCPEKLYALLLQCWRS 2477 Query: 463 DPAERPDFSEILEALKKIAEEV 398 +P ERP F L L+ ++ ++ Sbjct: 2478 EPWERPSFKRCLSTLQALSSDL 2499
>KIN16_CAEEL (P34892) Receptor-like tyrosine-protein kinase kin-16 precursor (EC| 2.7.10.1) Length = 495 Score = 53.9 bits (128), Expect = 4e-07 Identities = 27/73 (36%), Positives = 45/73 (61%), Gaps = 1/73 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFGI L+E+ T G++PY + P + + G R P++ H +L +L++ CW + Sbjct: 381 SDVWSFGICLYEIFTLGQLPYPDV-PSERIYEYMHSGRRCPQPQHCHVELYDLMKLCWHE 439 Query: 463 DPAERPDFSEILE 425 P RP+FS +E Sbjct: 440 KPELRPNFSNCVE 452
>EPHB1_RAT (P09759) Ephrin type-B receptor 1 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-2) (ELK) Length = 984 Score = 53.9 bits (128), Expect = 4e-07 Identities = 27/78 (34%), Positives = 49/78 (62%), Gaps = 1/78 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+S+GI++WE+++ G+ PY ++ Q + +++ R P + A L +L+ CWQ+ Sbjct: 805 SDVWSYGIVMWEVMSFGERPYWDMSN-QDVINAIEQDYRLPPPMDCPAALHQLMLDCWQK 863 Query: 463 DPAERPDFSEILEALKKI 410 D RP F+EI+ L K+ Sbjct: 864 DRNSRPRFAEIVNTLDKM 881
>EPHB1_HUMAN (P54762) Ephrin type-B receptor 1 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK) Length = 984 Score = 53.9 bits (128), Expect = 4e-07 Identities = 27/78 (34%), Positives = 49/78 (62%), Gaps = 1/78 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+S+GI++WE+++ G+ PY ++ Q + +++ R P + A L +L+ CWQ+ Sbjct: 805 SDVWSYGIVMWEVMSFGERPYWDMSN-QDVINAIEQDYRLPPPMDCPAALHQLMLDCWQK 863 Query: 463 DPAERPDFSEILEALKKI 410 D RP F+EI+ L K+ Sbjct: 864 DRNSRPRFAEIVNTLDKM 881
>KFMS_FSVMD (P00545) Tyrosine-protein kinase transforming protein fms (EC| 2.7.10.1) Length = 978 Score = 53.9 bits (128), Expect = 4e-07 Identities = 28/81 (34%), Positives = 44/81 (54%), Gaps = 1/81 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+S+GILLWE+ + G PY + +V+ G + P A + ++Q CW Sbjct: 868 SDVWSYGILLWEIFSLGLNPYPGILVNSKFYKLVKDGYQMAQPAFAPKNIYSIMQACWAL 927 Query: 463 DPAERPDFSEILEALKKIAEE 401 +P RP F +I L+K A+E Sbjct: 928 EPTRRPTFQQICSLLQKQAQE 948
>FES_FSVST (P00543) Tyrosine-protein kinase transforming protein Fes (EC| 2.7.10.2) Length = 477 Score = 53.9 bits (128), Expect = 4e-07 Identities = 30/78 (38%), Positives = 44/78 (56%), Gaps = 1/78 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFGILLWE + G PY L+ Q V+KG R P+ + L+++CW Sbjct: 396 SDVWSFGILLWETFSLGASPYPNLSNQQTRE-FVEKGGRLPCPELCPDAVFRLMEQCWAY 454 Query: 463 DPAERPDFSEILEALKKI 410 +P +RP FS + L+ I Sbjct: 455 EPGQRPSFSAFYQELQSI 472
>SRK1_SPOLA (P42686) Tyrosine-protein kinase isoform SRK1 (EC 2.7.10.2)| Length = 505 Score = 53.5 bits (127), Expect = 5e-07 Identities = 26/83 (31%), Positives = 48/83 (57%), Gaps = 1/83 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFG++L+E++T G+ PY +T + + +Q+ R P N + +++ CW++ Sbjct: 416 SDVWSFGVVLYEIITYGRFPYPGMTNPEV-LEKIQQNYRMPCPANCPKQFHDIMLDCWRE 474 Query: 463 DPAERPDFSEILEALKKIAEEVG 395 DPA RP F + L++ G Sbjct: 475 DPASRPTFETLQWQLEEFFNSEG 497
>LCK_SAISC (Q95KR7) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) Length = 508 Score = 53.5 bits (127), Expect = 5e-07 Identities = 29/91 (31%), Positives = 56/91 (61%), Gaps = 1/91 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFGIL+ E++T G+IPY +T + + +++G R P N +L +L+ +CW++ Sbjct: 420 SDVWSFGILMTEIVTHGRIPYPGMTNPEV-IQNLERGYRMPRPDNCPEELYKLMMQCWRE 478 Query: 463 DPAERPDFSEILEALKKIAEEVGDEHDGKHK 371 P +RP F + L+ + E+ +G+++ Sbjct: 479 RPDDRPTF----DYLRSVLEDFFTATEGQYQ 505
>LCK_AOTNA (Q5PXS1) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) Length = 508 Score = 53.5 bits (127), Expect = 5e-07 Identities = 30/91 (32%), Positives = 54/91 (59%), Gaps = 1/91 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFGILL E++T G+IPY +T + + +++G R P N +L L+ CW++ Sbjct: 420 SDVWSFGILLTEIVTHGRIPYPGMTNPEV-IQNLERGYRMVRPDNCPEELYHLMMLCWKE 478 Query: 463 DPAERPDFSEILEALKKIAEEVGDEHDGKHK 371 P +RP F + L+ + E+ +G+++ Sbjct: 479 RPEDRPTF----DYLRSVLEDFFTATEGQYQ 505
>BMX_HUMAN (P51813) Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2)| (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38) Length = 675 Score = 53.5 bits (127), Expect = 5e-07 Identities = 29/86 (33%), Positives = 51/86 (59%), Gaps = 1/86 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV++FGIL+WE+ + GK PY+ Q + V Q G R P A + +++ CW + Sbjct: 593 SDVWAFGILMWEVFSLGKQPYDLYDNSQVVLKVSQ-GHRLYRPHLASDTIYQIMYSCWHE 651 Query: 463 DPAERPDFSEILEALKKIAEEVGDEH 386 P +RP F ++L +++ + E+ D+H Sbjct: 652 LPEKRPTFQQLLSSIEPLREK--DKH 675
>VGFR2_COTJA (P52583) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Endothelial kinase receptor EK1) (Quek 1) (Quek1) Length = 1348 Score = 53.5 bits (127), Expect = 5e-07 Identities = 29/89 (32%), Positives = 48/89 (53%), Gaps = 1/89 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFG+LLWE+ + G PY + + +++G R P ++ + + CW Sbjct: 1079 SDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHG 1138 Query: 463 DPAERPDFSEILEALKKIAEEVGDEHDGK 377 DP +RP FSE++E L + + DGK Sbjct: 1139 DPKQRPTFSELVEHLGNLL-QANVRQDGK 1166
>MET_PIG (Q2QLE0) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1381 Score = 53.5 bits (127), Expect = 5e-07 Identities = 32/86 (37%), Positives = 45/86 (52%), Gaps = 1/86 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFG+LLWEL+T G PY + V ++Q G R P+ L E++ KCW Sbjct: 1264 SDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQ-GRRLLQPEYCPDPLYEVMLKCWHP 1322 Query: 463 DPAERPDFSEILEALKKIAEEVGDEH 386 RP FSE++ + I EH Sbjct: 1323 RAELRPSFSELVSRISAIFSTFIGEH 1348
>YES_CANFA (Q28923) Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2)| (p61-Yes) (c-Yes) Length = 538 Score = 53.5 bits (127), Expect = 5e-07 Identities = 30/76 (39%), Positives = 44/76 (57%), Gaps = 1/76 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFGIL EL T G++PY + + + V++G R P+ L EL+ CW++ Sbjct: 448 SDVWSFGILQTELTTKGRVPYPGMVNREV-LEQVERGYRMPCPQGCPESLHELMNLCWKK 506 Query: 463 DPAERPDFSEILEALK 416 DP ERP F I L+ Sbjct: 507 DPDERPTFEYIQSFLE 522
>FGFR1_RAT (Q04589) Basic fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) (FGFR-1) (bFGF-R) (MFR) Length = 822 Score = 53.5 bits (127), Expect = 5e-07 Identities = 27/78 (34%), Positives = 48/78 (61%), Gaps = 1/78 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFG+LLWE+ T G P + P++ ++++G R P N +L +++ CW Sbjct: 681 SDVWSFGVLLWEIFTLGGSPNPGV-PVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWNA 739 Query: 463 DPAERPDFSEILEALKKI 410 P++RP F +++E L +I Sbjct: 740 VPSQRPTFKQLVEDLDRI 757
>EPB1B_XENLA (Q91736) Ephrin type-B receptor 1-B (EC 2.7.10.1) (Tyrosine-protein| kinase receptor XELK) (Fragment) Length = 902 Score = 53.5 bits (127), Expect = 5e-07 Identities = 27/78 (34%), Positives = 48/78 (61%), Gaps = 1/78 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+S+GI++WE+++ G+ PY ++ Q + +++ R P + A L +L+ CWQ+ Sbjct: 723 SDVWSYGIVMWEVMSYGERPYWDMSN-QDVINAIEQDYRLPPPMDCPAALHQLMLDCWQK 781 Query: 463 DPAERPDFSEILEALKKI 410 D RP F EI+ L K+ Sbjct: 782 DRNSRPRFGEIVNTLDKM 799
>INSRR_MOUSE (Q9WTL4) Insulin receptor-related protein precursor (EC 2.7.10.1)| (IRR) (IR-related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain] Length = 1300 Score = 53.5 bits (127), Expect = 5e-07 Identities = 28/76 (36%), Positives = 47/76 (61%), Gaps = 1/76 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFG++LWE++T + PY+ L+ Q V+ G+ + +N +L EL++ CWQ Sbjct: 1173 SDVWSFGVVLWEIVTLAEQPYQGLSNEQVLKFVMDGGVLEEL-ENCPIQLQELMRLCWQH 1231 Query: 463 DPAERPDFSEILEALK 416 P RP F IL+ ++ Sbjct: 1232 SPRLRPTFVHILDRIQ 1247
>FAK2_HUMAN (Q14289) Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal| adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinas Length = 1009 Score = 53.5 bits (127), Expect = 5e-07 Identities = 27/78 (34%), Positives = 48/78 (61%), Gaps = 1/78 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+ F + +WE+L+ GK P+ +L + +GV++KG R P L L+ +CW Sbjct: 606 SDVWMFAVCMWEILSFGKQPFFWLEN-KDVIGVLEKGDRLPKPDLCPPVLYTLMTRCWDY 664 Query: 463 DPAERPDFSEILEALKKI 410 DP++RP F+E++ +L + Sbjct: 665 DPSDRPRFTELVCSLSDV 682
>MET_CANFA (Q75ZY9) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1382 Score = 53.5 bits (127), Expect = 5e-07 Identities = 32/86 (37%), Positives = 45/86 (52%), Gaps = 1/86 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFG+LLWEL+T G PY + V ++Q G R P+ L E++ KCW Sbjct: 1265 SDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQ-GRRLLQPEYCPDPLYEVMLKCWHP 1323 Query: 463 DPAERPDFSEILEALKKIAEEVGDEH 386 RP FSE++ + I EH Sbjct: 1324 RAELRPSFSELVSRISAIFSTFIGEH 1349
>VGFR3_HUMAN (P35916) Vascular endothelial growth factor receptor 3 precursor (EC| 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4) Length = 1298 Score = 53.5 bits (127), Expect = 5e-07 Identities = 28/83 (33%), Positives = 45/83 (54%), Gaps = 1/83 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFG+LLWE+ + G PY + + ++ G R P+ A + ++ CW Sbjct: 1095 SDVWSFGVLLWEIFSLGASPYPGVQINEEFCQRLRDGTRMRAPELATPAIRRIMLNCWSG 1154 Query: 463 DPAERPDFSEILEALKKIAEEVG 395 DP RP FSE++E L + + G Sbjct: 1155 DPKARPAFSELVEILGDLLQGRG 1177
>CSF1R_HUMAN (P07333) Macrophage colony-stimulating factor 1 receptor precursor| (CSF-1-R) (EC 2.7.10.1) (Fms proto-oncogene) (c-fms) (CD115 antigen) Length = 972 Score = 53.5 bits (127), Expect = 5e-07 Identities = 29/87 (33%), Positives = 46/87 (52%), Gaps = 1/87 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+S+GILLWE+ + G PY + +V+ G + P A + ++Q CW Sbjct: 836 SDVWSYGILLWEIFSLGLNPYPGILVNSKFYKLVKDGYQMAQPAFAPKNIYSIMQACWAL 895 Query: 463 DPAERPDFSEILEALKKIAEEVGDEHD 383 +P RP F +I L++ A+E E D Sbjct: 896 EPTHRPTFQQICSFLQEQAQEDRRERD 922
>SRC_RSVSE (P63185) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 53.5 bits (127), Expect = 5e-07 Identities = 31/74 (41%), Positives = 46/74 (62%), Gaps = 1/74 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFGILL EL T G++PY + + + V++G R P L +L+ +CW++ Sbjct: 442 SDVWSFGILLTELTTKGRVPYPGMGNGEV-LDRVERGYRMPCPPECPESLHDLMSQCWRR 500 Query: 463 DPAERPDFSEILEA 422 DP ERP F E L+A Sbjct: 501 DPEERPTF-EYLQA 513
>SRC_RSVP (P00526) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 53.5 bits (127), Expect = 5e-07 Identities = 28/68 (41%), Positives = 42/68 (61%), Gaps = 1/68 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFGILL EL T G++PY + + + V++G R P L +L+ +CW++ Sbjct: 442 SDVWSFGILLTELTTKGRVPYPGMVNREV-LDQVERGYRMPCPPECPESLHDLMCQCWRK 500 Query: 463 DPAERPDF 440 DP ERP F Sbjct: 501 DPEERPTF 508
>TIE1_BOVIN (Q06805) Tyrosine-protein kinase receptor Tie-1 precursor (EC| 2.7.10.1) Length = 1136 Score = 53.5 bits (127), Expect = 5e-07 Identities = 29/80 (36%), Positives = 49/80 (61%), Gaps = 1/80 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFG+LLWE+++ G PY +T + + Q R P+N ++ EL+++CW+ Sbjct: 1032 SDVWSFGVLLWEIVSLGGTPYCGMTCAELYEKLPQ-AYRMEQPRNCDDEVYELMRQCWRD 1090 Query: 463 DPAERPDFSEILEALKKIAE 404 P ERP F++I L ++ E Sbjct: 1091 RPYERPPFAQIALQLGRMLE 1110
>PGFRA_RAT (P20786) Alpha platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-alpha) Length = 1088 Score = 53.5 bits (127), Expect = 5e-07 Identities = 27/78 (34%), Positives = 46/78 (58%), Gaps = 4/78 (5%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+S+G+LLWE+ + G PY + ++ G R P +A +++ E++ +CW Sbjct: 875 SDVWSYGVLLWEIFSLGGTPYPGMMVDSTFYNKIKSGYRMAKPDHATSEVYEIMVQCWNS 934 Query: 463 DPAERPDF---SEILEAL 419 +P +RP F SEI+E L Sbjct: 935 EPEKRPSFYHLSEIVENL 952
>FRK_HUMAN (P42685) Tyrosine-protein kinase FRK (EC 2.7.10.2) (Nuclear| tyrosine protein kinase RAK) Length = 505 Score = 53.1 bits (126), Expect = 7e-07 Identities = 26/71 (36%), Positives = 43/71 (60%), Gaps = 1/71 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFGILL+E++T GK+PY +T Q + ++ + R P N + ++ +CW Sbjct: 414 SDVWSFGILLYEIITYGKMPYSGMTGAQV-IQMLAQNYRLPQPSNCPQQFYNIMLECWNA 472 Query: 463 DPAERPDFSEI 431 +P ERP F + Sbjct: 473 EPKERPTFETL 483
>RIPK1_MOUSE (Q60855) Receptor-interacting serine/threonine-protein kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein) Length = 656 Score = 53.1 bits (126), Expect = 7e-07 Identities = 26/78 (33%), Positives = 43/78 (55%), Gaps = 3/78 (3%) Frame = -2 Query: 640 ADVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIP---KNAHAKLTELLQKCW 470 +DV+SFGI+LW + K PYE + + V ++ G RP + + ++ L+++CW Sbjct: 210 SDVYSFGIVLWAIFAKKEPYENVICTEQFVICIKSGNRPNVEEILEYCPREIISLMERCW 269 Query: 469 QQDPAERPDFSEILEALK 416 Q P +RP F I E + Sbjct: 270 QAIPEDRPTFLGIEEEFR 287
>SRC_RSVPA (P31693) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 522 Score = 53.1 bits (126), Expect = 7e-07 Identities = 31/74 (41%), Positives = 46/74 (62%), Gaps = 1/74 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFGILL EL T G++PY + + + V++G R P L +L+ +CW++ Sbjct: 439 SDVWSFGILLTELTTKGRVPYPGMVNGEV-LDRVERGYRMPCPPECPESLHDLMCQCWRK 497 Query: 463 DPAERPDFSEILEA 422 DP ERP F E L+A Sbjct: 498 DPEERPTF-EYLQA 510
>XMRK_XIPMA (P13388) Melanoma receptor tyrosine-protein kinase precursor (EC| 2.7.10.1) Length = 1167 Score = 53.1 bits (126), Expect = 7e-07 Identities = 26/81 (32%), Positives = 47/81 (58%), Gaps = 1/81 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+S+G+ +WEL+T G PY+ + P + V++ G R P ++ ++ KCW Sbjct: 893 SDVWSYGVTVWELMTFGSKPYDGI-PAKEIASVLENGERLPQPPICTIEVYMIILKCWMI 951 Query: 463 DPAERPDFSEILEALKKIAEE 401 DP+ RP F E++ ++A + Sbjct: 952 DPSSRPRFRELVGEFSQMARD 972
>MET_HUMAN (P08581) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1390 Score = 53.1 bits (126), Expect = 7e-07 Identities = 31/86 (36%), Positives = 45/86 (52%), Gaps = 1/86 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFG++LWEL+T G PY + V ++Q G R P+ L E++ KCW Sbjct: 1264 SDVWSFGVVLWELMTRGAPPYPDVNTFDITVYLLQ-GRRLLQPEYCPDPLYEVMLKCWHP 1322 Query: 463 DPAERPDFSEILEALKKIAEEVGDEH 386 RP FSE++ + I EH Sbjct: 1323 KAEMRPSFSELVSRISAIFSTFIGEH 1348
>INSR_HUMAN (P06213) Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220| antigen) [Contains: Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1382 Score = 53.1 bits (126), Expect = 7e-07 Identities = 28/76 (36%), Positives = 46/76 (60%), Gaps = 1/76 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +D++SFG++LWE+ + + PY+ L+ Q V+ G P N ++T+L++ CWQ Sbjct: 1217 SDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDQ-PDNCPERVTDLMRMCWQF 1275 Query: 463 DPAERPDFSEILEALK 416 +P RP F EI+ LK Sbjct: 1276 NPKMRPTFLEIVNLLK 1291
>EPHB2_MOUSE (P54763) Ephrin type-B receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3) Length = 994 Score = 53.1 bits (126), Expect = 7e-07 Identities = 26/78 (33%), Positives = 48/78 (61%), Gaps = 1/78 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+S+GI++WE+++ G+ PY +T Q + +++ R P + + L +L+ CWQ+ Sbjct: 815 SDVWSYGIVMWEVMSYGERPYWDMTN-QDVINAIEQDYRLPPPMDCPSALHQLMLDCWQK 873 Query: 463 DPAERPDFSEILEALKKI 410 D RP F +I+ L K+ Sbjct: 874 DRNHRPKFGQIVNTLDKM 891
>EPHA4_MOUSE (Q03137) Ephrin type-A receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor SEK) (MPK-3) Length = 986 Score = 53.1 bits (126), Expect = 7e-07 Identities = 25/78 (32%), Positives = 50/78 (64%), Gaps = 1/78 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+S+GI++WE+++ G+ PY ++ Q + +++G R P + L +L+ CWQ+ Sbjct: 805 SDVWSYGIVMWEVMSYGERPYWDMSN-QDVIKAIEEGYRLPPPMDCPIALHQLMLDCWQK 863 Query: 463 DPAERPDFSEILEALKKI 410 + ++RP F +I+ L K+ Sbjct: 864 ERSDRPKFGQIVNMLDKL 881
>EPHA4_HUMAN (P54764) Ephrin type-A receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8) Length = 986 Score = 53.1 bits (126), Expect = 7e-07 Identities = 25/78 (32%), Positives = 50/78 (64%), Gaps = 1/78 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+S+GI++WE+++ G+ PY ++ Q + +++G R P + L +L+ CWQ+ Sbjct: 805 SDVWSYGIVMWEVMSYGERPYWDMSN-QDVIKAIEEGYRLPPPMDCPIALHQLMLDCWQK 863 Query: 463 DPAERPDFSEILEALKKI 410 + ++RP F +I+ L K+ Sbjct: 864 ERSDRPKFGQIVNMLDKL 881
>EPHA4_CHICK (Q07496) Ephrin type-A receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor CEK8) Length = 986 Score = 53.1 bits (126), Expect = 7e-07 Identities = 25/78 (32%), Positives = 50/78 (64%), Gaps = 1/78 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+S+GI++WE+++ G+ PY ++ Q + +++G R P + L +L+ CWQ+ Sbjct: 805 SDVWSYGIVMWEVMSYGERPYWDMSN-QDVIKAIEEGYRLPPPMDCPIALHQLMLDCWQK 863 Query: 463 DPAERPDFSEILEALKKI 410 + ++RP F +I+ L K+ Sbjct: 864 ERSDRPKFGQIVNMLDKL 881
>EPA4A_XENLA (Q91845) Ephrin type-A receptor 4-A precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor SEK-1) (xSEK-1) Length = 986 Score = 53.1 bits (126), Expect = 7e-07 Identities = 25/78 (32%), Positives = 50/78 (64%), Gaps = 1/78 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+S+GI++WE+++ G+ PY ++ Q + +++G R P + L +L+ CWQ+ Sbjct: 804 SDVWSYGIVMWEVMSYGERPYWDMSN-QDVIKAIEEGYRLPPPMDCPIALHQLMLDCWQK 862 Query: 463 DPAERPDFSEILEALKKI 410 + ++RP F +I+ L K+ Sbjct: 863 ERSDRPKFGQIVSMLDKL 880
>EPHB2_HUMAN (P29323) Ephrin type-B receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen) Length = 1055 Score = 53.1 bits (126), Expect = 7e-07 Identities = 26/78 (33%), Positives = 48/78 (61%), Gaps = 1/78 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+S+GI++WE+++ G+ PY +T Q + +++ R P + + L +L+ CWQ+ Sbjct: 807 SDVWSYGIVMWEVMSYGERPYWDMTN-QDVINAIEQDYRLPPPMDCPSALHQLMLDCWQK 865 Query: 463 DPAERPDFSEILEALKKI 410 D RP F +I+ L K+ Sbjct: 866 DRNHRPKFGQIVNTLDKM 883
>LCK_MOUSE (P06240) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) Length = 508 Score = 52.8 bits (125), Expect = 9e-07 Identities = 28/75 (37%), Positives = 45/75 (60%), Gaps = 1/75 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFGILL E++T G+IPY +T + + +++G R P N +L L+ CW++ Sbjct: 420 SDVWSFGILLTEIVTHGRIPYPGMTNPEV-IQNLERGYRMVRPDNCPEELYHLMMLCWKE 478 Query: 463 DPAERPDFSEILEAL 419 P +RP F + L Sbjct: 479 RPEDRPTFDYLRSVL 493
>VGFR2_RAT (O08775) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Protein-tyrosine kinase receptor flk-1) (Fetal liver kinase 1) Length = 1343 Score = 52.8 bits (125), Expect = 9e-07 Identities = 28/87 (32%), Positives = 48/87 (55%), Gaps = 1/87 (1%) Frame = -2 Query: 634 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 458 V+SFG+LLWE+ + G PY + + +++G R P ++ + + CW +DP Sbjct: 1084 VWSFGVLLWEIFSLGASPYPGVKIDEKFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHEDP 1143 Query: 457 AERPDFSEILEALKKIAEEVGDEHDGK 377 +RP FSE++E L + + + DGK Sbjct: 1144 NQRPAFSELVEHLGNLL-QANAQQDGK 1169
>SRC_MOUSE (P05480) Neuronal proto-oncogene tyrosine-protein kinase Src (EC| 2.7.10.2) (p60-Src) (c-Src) (pp60c-src) Length = 540 Score = 52.8 bits (125), Expect = 9e-07 Identities = 30/74 (40%), Positives = 46/74 (62%), Gaps = 1/74 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFGILL EL T G++PY + + + V++G R P L +L+ +CW++ Sbjct: 450 SDVWSFGILLTELTTKGRVPYPGMVNREV-LDQVERGYRMPCPPECPESLHDLMCQCWRK 508 Query: 463 DPAERPDFSEILEA 422 +P ERP F E L+A Sbjct: 509 EPEERPTF-EYLQA 521
>ERBB_AVIEU (P11273) Tyrosine-protein kinase transforming protein erbB (EC| 2.7.10.1) Length = 540 Score = 52.8 bits (125), Expect = 9e-07 Identities = 27/81 (33%), Positives = 44/81 (54%), Gaps = 1/81 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+S+G+ +WEL+T G PY+ + P V++KG R P + ++ KCW Sbjct: 315 SDVWSYGVTVWELMTFGSKPYDGI-PASEISSVLEKGERLPQPPICTIDVYMIMVKCWMS 373 Query: 463 DPAERPDFSEILEALKKIAEE 401 D RP F E++ K+A + Sbjct: 374 DADSRPKFRELIAEFSKMARD 394
>SRC_RAT (Q9WUD9) Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2)| (p60-Src) (c-Src) (pp60c-src) Length = 535 Score = 52.8 bits (125), Expect = 9e-07 Identities = 30/74 (40%), Positives = 46/74 (62%), Gaps = 1/74 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFGILL EL T G++PY + + + V++G R P L +L+ +CW++ Sbjct: 445 SDVWSFGILLTELTTKGRVPYPGMVNREV-LDQVERGYRMPCPPECPESLHDLMCQCWRK 503 Query: 463 DPAERPDFSEILEA 422 +P ERP F E L+A Sbjct: 504 EPEERPTF-EYLQA 516
>SRC_HUMAN (P12931) Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2)| (p60-Src) (c-Src) (pp60c-src) Length = 535 Score = 52.8 bits (125), Expect = 9e-07 Identities = 30/74 (40%), Positives = 46/74 (62%), Gaps = 1/74 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFGILL EL T G++PY + + + V++G R P L +L+ +CW++ Sbjct: 445 SDVWSFGILLTELTTKGRVPYPGMVNREV-LDQVERGYRMPCPPECPESLHDLMCQCWRK 503 Query: 463 DPAERPDFSEILEA 422 +P ERP F E L+A Sbjct: 504 EPEERPTF-EYLQA 516
>PTK7_HUMAN (Q13308) Tyrosine-protein kinase-like 7 precursor (Colon carcinoma| kinase 4) (CCK-4) Length = 1070 Score = 52.8 bits (125), Expect = 9e-07 Identities = 30/81 (37%), Positives = 46/81 (56%), Gaps = 7/81 (8%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPY------EYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELL 482 +DV++ G+L+WE+ T G++P+ E L LQA + + P+ +KL L+ Sbjct: 987 SDVWASGVLMWEVFTHGEMPHGGQADDEVLADLQAGKARLPQ------PEGCPSKLYRLM 1040 Query: 481 QKCWQQDPAERPDFSEILEAL 419 Q+CW P +RP FSEI AL Sbjct: 1041 QRCWALSPKDRPSFSEIASAL 1061
>SRK3_SPOLA (P42689) Tyrosine-protein kinase SRK3 (EC 2.7.10.2) (Fragment)| Length = 334 Score = 52.4 bits (124), Expect = 1e-06 Identities = 28/81 (34%), Positives = 49/81 (60%), Gaps = 1/81 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFG+L+ E++T G++PY +T Q + V +G R P+ L +++ CW+ Sbjct: 243 SDVWSFGVLISEIVTHGRMPYPGMTNRQV-LEAVDRGYRMPCPEGCPDPLYKIMLSCWKH 301 Query: 463 DPAERPDFSEILEALKKIAEE 401 +P +RP F E+LK + E+ Sbjct: 302 EPDDRPTF----ESLKNLLED 318
>MIPR_LYMST (Q25410) Putative molluscan insulin-related peptide(s) receptor| precursor (EC 2.7.10.1) [Contains: Putative molluscan insulin-related peptide(s) receptor alpha chain; Putative molluscan insulin-related peptide(s) receptor beta chain] Length = 1607 Score = 52.4 bits (124), Expect = 1e-06 Identities = 25/75 (33%), Positives = 45/75 (60%), Gaps = 1/75 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+S+G+++WE++T PY+ L+ + V + G +P+N ++ L+Q CW + Sbjct: 1231 SDVWSYGVVMWEMVTLAAQPYQGLSN-EEVVKFISDGYIMELPENCPNEMAYLMQHCWAK 1289 Query: 463 DPAERPDFSEILEAL 419 P +RP F I+E L Sbjct: 1290 KPNQRPTFKAIIEYL 1304
>SRMS_HUMAN (Q9H3Y6) Tyrosine-protein kinase Srms (EC 2.7.10.2)| Length = 488 Score = 52.4 bits (124), Expect = 1e-06 Identities = 29/78 (37%), Positives = 46/78 (58%), Gaps = 1/78 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFG+LL E+ T G+ PYE +T + + + +G R P A++ L+ +CW+ Sbjct: 407 SDVWSFGVLLHEVFTYGQCPYEGMTNHET-LQQIMRGYRLPRPAACPAEVYVLMLECWRS 465 Query: 463 DPAERPDFSEILEALKKI 410 P ERP F+ + E L I Sbjct: 466 SPEERPSFATLREKLHAI 483
>EPHA1_HUMAN (P21709) Ephrin type-A receptor 1 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH) Length = 976 Score = 52.4 bits (124), Expect = 1e-06 Identities = 28/78 (35%), Positives = 47/78 (60%), Gaps = 1/78 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFGI++WE+L+ G PY ++ Q + ++ G R P + A L EL++ CW Sbjct: 807 SDVWSFGIVMWEVLSFGDKPYGEMSN-QEVMKSIEDGYRLPPPVDCPAPLYELMKNCWAY 865 Query: 463 DPAERPDFSEILEALKKI 410 D A RP F ++ L+++ Sbjct: 866 DRARRPHFQKLQAHLEQL 883
>FPS_DROME (P18106) Tyrosine-protein kinase Fps85D (EC 2.7.10.2) (dFer)| Length = 1325 Score = 52.4 bits (124), Expect = 1e-06 Identities = 27/85 (31%), Positives = 44/85 (51%), Gaps = 1/85 (1%) Frame = -2 Query: 637 DVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQD 461 DV+S+GIL+WE+ + G PY +T +A + G R PK+ ++ L+ +CW D Sbjct: 1242 DVWSYGILMWEIFSKGDTPYSGMTNSRARERI-DTGYRMPTPKSTPEEMYRLMLQCWAAD 1300 Query: 460 PAERPDFSEILEALKKIAEEVGDEH 386 RP F EI + + + + H Sbjct: 1301 AESRPHFDEIYNVVDALILRLDNSH 1325
>HTK7_HYDAT (Q25197) Putative insulin-like peptide receptor precursor (EC| 2.7.10.1) Length = 1477 Score = 52.4 bits (124), Expect = 1e-06 Identities = 31/85 (36%), Positives = 45/85 (52%), Gaps = 1/85 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFG++LWE+ T PY+ T Q V+ G P+ +L E + CW + Sbjct: 1233 SDVWSFGVVLWEICTLASQPYQGKTNEQVLNFVLSNG-HLDYPEGCDYQLREFMSLCWHR 1291 Query: 463 DPAERPDFSEILEALKKIAEEVGDE 389 DP RP F EI+ L+ EV D+ Sbjct: 1292 DPKMRPSFLEIVHVLE---NEVDDD 1313
>SRC_RSVSA (P00524) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 52.4 bits (124), Expect = 1e-06 Identities = 31/74 (41%), Positives = 46/74 (62%), Gaps = 1/74 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFGILL EL T G++PY + + + V++G R P L +L+ +CW++ Sbjct: 442 SDVWSFGILLTELTTKGRVPYPGMGNGEV-LDRVERGYRMPCPPECPESLHDLMCQCWRR 500 Query: 463 DPAERPDFSEILEA 422 DP ERP F E L+A Sbjct: 501 DPEERPTF-EYLQA 513
>SRC_AVISR (P00525) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 52.4 bits (124), Expect = 1e-06 Identities = 31/74 (41%), Positives = 46/74 (62%), Gaps = 1/74 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFGILL EL T G++PY + + + V++G R P L +L+ +CW++ Sbjct: 442 SDVWSFGILLTELTTKGRVPYPGMGNGEV-LDRVERGYRMPCPPECPESLHDLMCQCWRR 500 Query: 463 DPAERPDFSEILEA 422 DP ERP F E L+A Sbjct: 501 DPEERPTF-EYLQA 513
>SRMS_MOUSE (Q62270) Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70)| Length = 496 Score = 52.4 bits (124), Expect = 1e-06 Identities = 30/78 (38%), Positives = 47/78 (60%), Gaps = 1/78 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFGILL+E+ T G+ PYE +T + + + +G R P A++ L+ +CW+ Sbjct: 411 SDVWSFGILLYEVFTYGQCPYEGMTNHET-LQQISRGYRLPRPAVCPAEVYVLMVECWKG 469 Query: 463 DPAERPDFSEILEALKKI 410 P ERP F+ + E L I Sbjct: 470 SPEERPTFAILREKLNAI 487
>LTK_HUMAN (P29376) Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1)| (Protein tyrosine kinase 1) Length = 864 Score = 52.0 bits (123), Expect = 1e-06 Identities = 28/80 (35%), Positives = 44/80 (55%), Gaps = 1/80 (1%) Frame = -2 Query: 637 DVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQD 461 D +SFG+LLWE+ + G +PY T Q + V G R P+ + ++ +CWQ + Sbjct: 705 DSWSFGVLLWEIFSLGYMPYPGRTN-QEVLDFVVGGGRMDPPRGCPGPVYRIMTQCWQHE 763 Query: 460 PAERPDFSEILEALKKIAEE 401 P RP F+ ILE L+ ++ Sbjct: 764 PELRPSFASILERLQYCTQD 783
>EPHA1_MOUSE (Q60750) Ephrin type-A receptor 1 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ESK) Length = 977 Score = 52.0 bits (123), Expect = 1e-06 Identities = 28/78 (35%), Positives = 47/78 (60%), Gaps = 1/78 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+SFGI++WE+L+ G PY ++ Q + ++ G R P + A L EL++ CW Sbjct: 808 SDVWSFGIVMWEVLSFGDKPYGEMSN-QEVMKSIEDGYRLPPPVDCPAPLYELMKNCWAY 866 Query: 463 DPAERPDFSEILEALKKI 410 D A RP F ++ L+++ Sbjct: 867 DRARRPHFLQLQAHLEQL 884
>EPHB2_COTJA (Q90344) Ephrin type-B receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor QEK5) Length = 987 Score = 52.0 bits (123), Expect = 1e-06 Identities = 26/78 (33%), Positives = 47/78 (60%), Gaps = 1/78 (1%) Frame = -2 Query: 640 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 464 +DV+S+GI++WE+++ G+ PY +T Q + +++ R P + L +L+ CWQ+ Sbjct: 808 SDVWSYGIVMWEVMSYGERPYWDMTN-QDVINAIEQDYRLPPPMDCPNALHQLMLDCWQK 866 Query: 463 DPAERPDFSEILEALKKI 410 D RP F +I+ L K+ Sbjct: 867 DRNHRPKFGQIVNTLDKM 884 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 89,195,650 Number of Sequences: 219361 Number of extensions: 1793765 Number of successful extensions: 6378 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 5724 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5931 length of database: 80,573,946 effective HSP length: 108 effective length of database: 56,882,958 effective search space used: 5972710590 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
