ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | rbags3b11 |
|---|---|
| Clone Library Name | barley_pub |
>HEMH_HORVU (P42045) Ferrochelatase-2, chloroplast precursor (EC 4.99.1.1)| (Ferrochelatase II) (Protoheme ferro-lyase 2) (Heme synthetase 2) Length = 484 Score = 338 bits (867), Expect = 8e-93 Identities = 171/171 (100%), Positives = 171/171 (100%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS 441 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS Sbjct: 314 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS 373 Query: 440 LLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVEALP 261 LLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVEALP Sbjct: 374 LLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVEALP 433 Query: 260 SASAMATRKVKDTDSDMDMMHYLTKMFLGSVLAFFLLLSPRLVSAFRNTLQ 108 SASAMATRKVKDTDSDMDMMHYLTKMFLGSVLAFFLLLSPRLVSAFRNTLQ Sbjct: 434 SASAMATRKVKDTDSDMDMMHYLTKMFLGSVLAFFLLLSPRLVSAFRNTLQ 484
>HEMH_CUCSA (P42044) Ferrochelatase-2, chloroplast precursor (EC 4.99.1.1)| (Ferrochelatase II) (Protoheme ferro-lyase 2) (Heme synthetase 2) Length = 514 Score = 256 bits (653), Expect = 5e-68 Identities = 127/168 (75%), Positives = 140/168 (83%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS 441 GDPY+DQME+CI LIM+ELK+RG N+HTLAYQSRVGPVQWLKPYTDEVLVELGQKG+KS Sbjct: 320 GDPYKDQMEECICLIMQELKARGIGNEHTLAYQSRVGPVQWLKPYTDEVLVELGQKGIKS 379 Query: 440 LLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVEALP 261 LLAVPVSFVSEHIETLEEIDMEY+ LALESGI+NWGRVPAL C SSFISDLADAV+EALP Sbjct: 380 LLAVPVSFVSEHIETLEEIDMEYKHLALESGIQNWGRVPALNCNSSFISDLADAVIEALP 439 Query: 260 SASAMATRKVKDTDSDMDMMHYLTKMFLGSVLAFFLLLSPRLVSAFRN 117 SA+A+A D D Y K+ GSVLAF LLLSP+ FRN Sbjct: 440 SATALAPHTSSTDADDHDPFLYAIKLLFGSVLAFILLLSPKAFMVFRN 487
>HEMH1_ARATH (P42043) Ferrochelatase-1, chloroplast/mitochondrial precursor (EC| 4.99.1.1) (Ferrochelatase I) (Protoheme ferro-lyase 1) (Heme synthetase 1) Length = 466 Score = 255 bits (652), Expect = 6e-68 Identities = 130/171 (76%), Positives = 145/171 (84%), Gaps = 3/171 (1%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS 441 GDPY+ QME+CI LIMEELK+RG LNDH LAYQSRVGPVQWLKPYTDEVLV+LG+ GVKS Sbjct: 295 GDPYQKQMEECIDLIMEELKARGVLNDHKLAYQSRVGPVQWLKPYTDEVLVDLGKSGVKS 354 Query: 440 LLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVEALP 261 LLAVPVSFVSEHIETLEEIDMEYRELALESG+ENWGRVPALG T SFI+DLADAV+E+LP Sbjct: 355 LLAVPVSFVSEHIETLEEIDMEYRELALESGVENWGRVPALGLTPSFITDLADAVIESLP 414 Query: 260 SASAMATRK--VKDTDSD-MDMMHYLTKMFLGSVLAFFLLLSPRLVSAFRN 117 SA AM+ V DS+ D Y+ KMF GS+LAF LLLSP++ AFRN Sbjct: 415 SAEAMSNPNAVVDSEDSESSDAFSYIVKMFFGSILAFVLLLSPKMFHAFRN 465
>HEMH_ORYSA (O22101) Ferrochelatase-2, chloroplast precursor (EC 4.99.1.1)| (Ferrochelatase II) (Protoheme ferro-lyase 2) (Heme synthetase 2) Length = 526 Score = 203 bits (517), Expect = 3e-52 Identities = 95/131 (72%), Positives = 115/131 (87%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS 441 GDPY+ +ME+C+ LIMEEL+ RG N TLAYQSRVGPV+WL+PYTDE ++ELGQKGVKS Sbjct: 319 GDPYKAEMEECVDLIMEELEKRGITNSCTLAYQSRVGPVEWLRPYTDETIIELGQKGVKS 378 Query: 440 LLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVEALP 261 LLAVP+SFVSEHIETLEEID+EY+ELALESGI++WGRVPALGC +FI+DLADAV+E+LP Sbjct: 379 LLAVPISFVSEHIETLEEIDVEYKELALESGIKHWGRVPALGCEPTFITDLADAVIESLP 438 Query: 260 SASAMATRKVK 228 AMA ++ Sbjct: 439 YVGAMAVSNLE 449
>HEMH2_ARATH (O04921) Ferrochelatase-2, chloroplast precursor (EC 4.99.1.1)| (Ferrochelatase II) (Protoheme ferro-lyase 2) (Heme synthetase 2) Length = 512 Score = 192 bits (489), Expect = 5e-49 Identities = 93/135 (68%), Positives = 112/135 (82%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS 441 GDPY+ +ME+C+ LIMEEL R N +TLAYQSRVGPV+WLKPYT+E + ELG+KGV++ Sbjct: 306 GDPYKAEMEECVDLIMEELDKRKITNAYTLAYQSRVGPVEWLKPYTEEAITELGKKGVEN 365 Query: 440 LLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVEALP 261 LLAVP+SFVSEHIETLEEID+EY+ELAL+SGI+NWGRVPALG FISDLADAVVE+LP Sbjct: 366 LLAVPISFVSEHIETLEEIDVEYKELALKSGIKNWGRVPALGTEPMFISDLADAVVESLP 425 Query: 260 SASAMATRKVKDTDS 216 AMA ++ S Sbjct: 426 YVGAMAVSNLEARQS 440
>HEMH_ANASP (Q8YQR8) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 388 Score = 147 bits (372), Expect = 2e-35 Identities = 74/123 (60%), Positives = 93/123 (75%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS 441 GDPY+ ++E+C ALIM+ L N HTLAYQSRVGPV+WL+PYT++ L ELG +GVK Sbjct: 207 GDPYQQEIEECTALIMQTLNRP---NPHTLAYQSRVGPVEWLQPYTEDALKELGAQGVKD 263 Query: 440 LLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVEALP 261 L+ VP+SFVSEHIETL+EID+EYRE+A E+GI N+ RVPA FI LAD V++AL Sbjct: 264 LVVVPISFVSEHIETLQEIDIEYREIAEEAGIHNFRRVPAPNTHPVFIRALADLVIDALN 323 Query: 260 SAS 252 S Sbjct: 324 KPS 326
>HEMH_PROMA (Q7VD58) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 391 Score = 144 bits (364), Expect = 2e-34 Identities = 71/120 (59%), Positives = 93/120 (77%), Gaps = 1/120 (0%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEEL-KSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVK 444 GDPY+D+++DC LI++++ KS G N +TL+YQSRVGP +WLKPYT+EVL ELG GVK Sbjct: 207 GDPYKDEIQDCALLIIDKVEKSLGFSNSYTLSYQSRVGPEEWLKPYTEEVLEELGANGVK 266 Query: 443 SLLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVEAL 264 L+ VP+SFVSEHIETL+EID+EY+++AL +GI N+ RV AL FI+ LAD V L Sbjct: 267 ELIVVPISFVSEHIETLQEIDIEYKKIALNNGIINFRRVKALDTYPLFINGLADLVASCL 326
>HEMH_SYNP6 (Q5N2B2) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 387 Score = 144 bits (363), Expect = 2e-34 Identities = 73/119 (61%), Positives = 90/119 (75%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS 441 GDPY+ ++EDC IME L G N TLAYQSRVGPV+WL+PYT++ L EL ++GVK Sbjct: 207 GDPYQREIEDCTRKIMETL---GRSNPWTLAYQSRVGPVEWLQPYTEDALEELAERGVKD 263 Query: 440 LLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVEAL 264 L+ VP+SFVSEHIETLEEID+EYRE+A E+GIE + RVPAL FI DL+D V + L Sbjct: 264 LVVVPISFVSEHIETLEEIDIEYREIAEEAGIERFLRVPALNTHPLFIQDLSDLVEQTL 322
>HEMH_SYNEL (Q8DGU6) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 388 Score = 144 bits (363), Expect = 2e-34 Identities = 72/119 (60%), Positives = 93/119 (78%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS 441 GDPY++++E C+ LIM L N H LAYQSRVGPV+WL+PYT++V++EL +GVK+ Sbjct: 208 GDPYQEEIEACVRLIMAALNRP---NAHVLAYQSRVGPVEWLQPYTEDVILELAAQGVKT 264 Query: 440 LLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVEAL 264 L+ VP+SFVSEHIETL+EID+EYRE+A E+GIE + RVPAL + FIS LA V EAL Sbjct: 265 LVVVPISFVSEHIETLQEIDIEYREIAAEAGIEVFRRVPALNDHNGFISALAQLVKEAL 323
>HEMH_GLOVI (Q7NMC7) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 327 Score = 142 bits (358), Expect = 8e-34 Identities = 70/119 (58%), Positives = 92/119 (77%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS 441 GDPY+ Q E+ + L+M+ L G N H+LAYQSRVGPV+WLKPYT++ + EL QKGV+S Sbjct: 207 GDPYQRQTEETVDLVMQSL---GRPNAHSLAYQSRVGPVEWLKPYTEDTINELAQKGVRS 263 Query: 440 LLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVEAL 264 LLAVPVSF+SEHIETL+EI++EYRE+A +GI ++ R AL +FI DLA+ V+E L Sbjct: 264 LLAVPVSFISEHIETLQEIEIEYREVAEAAGIHDFRRAKALNVNKTFIDDLAEMVIENL 322
>HEMH_PROMP (Q7V2F5) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 391 Score = 140 bits (354), Expect = 2e-33 Identities = 69/120 (57%), Positives = 92/120 (76%), Gaps = 1/120 (0%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEEL-KSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVK 444 GDPY++Q+EDC LI++EL K G N +TL+YQSRVGPV+WLKPYT+EVL +LG+ V Sbjct: 207 GDPYKEQIEDCSLLIIDELEKYLGHTNPYTLSYQSRVGPVEWLKPYTEEVLTDLGKAKVN 266 Query: 443 SLLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVEAL 264 L+ VP+SFV EHIETL+EID+EY+E+A ++GI N+ RV AL +FI L++ VV L Sbjct: 267 DLIVVPISFVGEHIETLQEIDIEYKEIAEKAGIVNFRRVKALNTHPTFIDGLSELVVSCL 326
>HEMH_SYNPX (Q7U5G0) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 391 Score = 140 bits (353), Expect = 3e-33 Identities = 72/120 (60%), Positives = 86/120 (71%), Gaps = 1/120 (0%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSR-GTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVK 444 GDPY+ Q+E C LIM+ L G N HTLAYQSRVGPV+WLKPYT+E L +LG+ Sbjct: 207 GDPYQQQIEACTDLIMKSLAEHMGHSNPHTLAYQSRVGPVEWLKPYTEEALEQLGEAKTN 266 Query: 443 SLLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVEAL 264 L+ VP+SFVSEHIETLEEID+EYRELA E+G+ N+ RV AL FI LAD V +L Sbjct: 267 DLVVVPISFVSEHIETLEEIDIEYRELATEAGVVNFRRVRALDTYPPFIEGLADLVTTSL 326
>HEMH_SYNY3 (P54225) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 387 Score = 139 bits (350), Expect = 7e-33 Identities = 70/119 (58%), Positives = 89/119 (74%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS 441 GDPY+ ++E C LIM L N +TLAYQSRVGPV+WLKPYT+E L +LG +G+ Sbjct: 207 GDPYQAEIEACTRLIMRTLDRP---NQYTLAYQSRVGPVEWLKPYTEEALQKLGAEGIDD 263 Query: 440 LLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVEAL 264 LL VP+SFVSEHIETL+EID+EYRE+A E+GI+N+ RVPAL FI LA V+++L Sbjct: 264 LLVVPISFVSEHIETLQEIDIEYREIAEEAGIDNFQRVPALNTHPVFIDALAQMVMDSL 322
>HEMH_PROMM (Q7V6C6) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 391 Score = 138 bits (347), Expect = 1e-32 Identities = 68/120 (56%), Positives = 91/120 (75%), Gaps = 1/120 (0%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSR-GTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVK 444 GDPY+ ++E C LIM EL++ G N H+LAYQSRVGP +W++PYTD+V+ +LG+ G + Sbjct: 207 GDPYQKEIEACTTLIMAELENLLGYGNPHSLAYQSRVGPEEWIQPYTDQVIEQLGEAGTR 266 Query: 443 SLLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVEAL 264 L+ VP+SFVSEHIETL E+D+EYRELA E+GI ++ RVPAL +FI LAD V +L Sbjct: 267 DLVVVPISFVSEHIETLAELDIEYRELATEAGIVHFRRVPALDTYPTFIEGLADLVGSSL 326
>HEMH_AQUAE (O67083) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 309 Score = 111 bits (277), Expect = 2e-24 Identities = 61/115 (53%), Positives = 76/115 (66%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS 441 GDPY++Q E + LIME ++TLAYQS+VG +WL+P TDEV+ L +K VK Sbjct: 195 GDPYQEQTEKTVKLIMENFPEV----EYTLAYQSKVGFGKWLEPSTDEVIRNLIKKEVKK 250 Query: 440 LLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAV 276 LL +P+SFVSEH ETL E+D +YRELA E G E + RVP L FIS L D V Sbjct: 251 LLVIPISFVSEHSETLYELDKQYRELAQELGYEEFVRVPTLRTNPYFISALEDLV 305
>HEMH_GEOSL (Q747F5) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 317 Score = 108 bits (270), Expect = 1e-23 Identities = 57/115 (49%), Positives = 76/115 (66%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS 441 GDPY D + + + L+ME + H LA+QSR GPV+WL+P TDE+L L VK+ Sbjct: 202 GDPYLDHIRETVRLVMERFEGV----THHLAFQSRAGPVKWLEPSTDEMLEHLAAHQVKN 257 Query: 440 LLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAV 276 LL VP+SFVS+HIETL EID+EY + A + G + R P+L + +FIS LAD V Sbjct: 258 LLIVPLSFVSDHIETLHEIDIEYAQEAHKLGYSRFRRSPSLNTSPTFISCLADLV 312
>HEMH_RICTY (Q68VM9) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 342 Score = 96.3 bits (238), Expect = 7e-20 Identities = 50/116 (43%), Positives = 78/116 (67%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS 441 GDPY Q+++ + I++EL + D+ + YQSRVGP++WLKP T E +EL K K Sbjct: 198 GDPYSFQIKETVNKIVKELNIKDL--DYKITYQSRVGPIEWLKPST-EYEIELAGKLKKD 254 Query: 440 LLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVV 273 ++ VP+SFVSEH+ETL E+D+EY+ +A + I+ + R+P LG FI+ L + ++ Sbjct: 255 IIIVPISFVSEHVETLVELDIEYKFIADKYNIQ-YTRIPTLGTNKIFINSLTNILI 309
>HEMH_XENLA (O57478) Ferrochelatase, mitochondrial precursor (EC 4.99.1.1)| (Protoheme ferro-lyase) (Heme synthetase) Length = 411 Score = 95.9 bits (237), Expect = 8e-20 Identities = 53/123 (43%), Positives = 76/123 (61%), Gaps = 1/123 (0%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS 441 GDPY ++ + +ME L G N + L +QS+VGP+ WL P TDE + L Q+G K+ Sbjct: 260 GDPYPQEVGATVQKVMERL---GFSNPYRLVWQSKVGPMAWLGPQTDESIKGLCQRGKKN 316 Query: 440 LLAVPVSFVSEHIETLEEIDMEYRE-LALESGIENWGRVPALGCTSSFISDLADAVVEAL 264 +L VP++F S+HIETL E+D+EY + LA E G+EN R +L F LAD V+ + Sbjct: 317 ILLVPIAFTSDHIETLYELDIEYAQVLAKECGVENIRRSESLNGNPLFSKALADLVLSHM 376 Query: 263 PSA 255 S+ Sbjct: 377 KSS 379
>HEMH_RICPR (Q9ZC84) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 342 Score = 95.1 bits (235), Expect = 1e-19 Identities = 49/116 (42%), Positives = 79/116 (68%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS 441 GDPY Q+++ + I++EL + D+ + YQSRVGP++WLKP T++ +EL K K Sbjct: 198 GDPYSFQIKETVNKIVKELNIKDL--DYKITYQSRVGPIEWLKPNTEDE-IELAGKLKKD 254 Query: 440 LLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVV 273 ++ VP+SFVSEH+ETL E+D+EY+ +A + I+ + R+P LG FI+ L + ++ Sbjct: 255 IIIVPISFVSEHVETLVELDIEYKLIADKYKIQ-YTRIPTLGTNKIFINSLTNILL 309
>HEMH_RICCN (Q92FV4) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 342 Score = 95.1 bits (235), Expect = 1e-19 Identities = 49/116 (42%), Positives = 79/116 (68%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS 441 GDPY Q+++ + I++EL + D+ + YQSRVGP++WLKP T++ +EL K K Sbjct: 198 GDPYSFQIKETVQAIVKELNIKDL--DYKITYQSRVGPIEWLKPNTEDE-IELAGKLKKD 254 Query: 440 LLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVV 273 ++ VP+SFVSEH+ETL E+D+EY+ +A + I+ + R+P LG FI+ L + ++ Sbjct: 255 IIIVPISFVSEHVETLVELDIEYKLIADKYEIQ-YIRIPTLGTNKIFINSLTNILL 309
>HEMH_BOVIN (P22600) Ferrochelatase, mitochondrial precursor (EC 4.99.1.1)| (Protoheme ferro-lyase) (Heme synthetase) Length = 416 Score = 94.7 bits (234), Expect = 2e-19 Identities = 53/129 (41%), Positives = 78/129 (60%), Gaps = 1/129 (0%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS 441 GDPY ++ + +M++L G N + L +QS+VGP+ WL P TDE + L ++G K+ Sbjct: 266 GDPYPQEVGATVQRVMDKL---GYSNPYRLVWQSKVGPMPWLGPQTDEAIKGLCKRGRKN 322 Query: 440 LLAVPVSFVSEHIETLEEIDMEYRE-LALESGIENWGRVPALGCTSSFISDLADAVVEAL 264 +L VP++F S+HIETL E+D+EY + LA E G+EN R +L F LAD V L Sbjct: 323 ILLVPIAFTSDHIETLYELDIEYSQVLASECGLENIRRAESLNGNPLFSKALADLVHSHL 382 Query: 263 PSASAMATR 237 S +T+ Sbjct: 383 QSKERCSTQ 391
>HEMH_CHICK (O42479) Ferrochelatase, mitochondrial precursor (EC 4.99.1.1)| (Protoheme ferro-lyase) (Heme synthetase) Length = 402 Score = 94.7 bits (234), Expect = 2e-19 Identities = 52/122 (42%), Positives = 74/122 (60%), Gaps = 1/122 (0%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS 441 GDPY ++ + +ME+L N + L +QS+VGP+ WL P TDE + L Q+G K+ Sbjct: 252 GDPYPQEVGATVQRVMEKLNHS---NPYRLVWQSKVGPMPWLVPQTDETIKGLCQRGKKN 308 Query: 440 LLAVPVSFVSEHIETLEEIDMEYRE-LALESGIENWGRVPALGCTSSFISDLADAVVEAL 264 +L VP++F S+HIETL E+D+EY + LA E G+EN R +L F LAD V + Sbjct: 309 MLLVPIAFTSDHIETLYELDIEYAQVLANECGVENIRRAESLNGNPLFSKALADLVCSHI 368 Query: 263 PS 258 S Sbjct: 369 QS 370
>HEMH_DESPS (Q6APB0) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 320 Score = 92.8 bits (229), Expect = 7e-19 Identities = 50/118 (42%), Positives = 74/118 (62%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS 441 GDPY + + I I E RG L +QS+ GPV+WL+P T +VL++L Q+GVK+ Sbjct: 204 GDPYVEHTKQSIGAIEEITGKRGRL-----CFQSKSGPVEWLEPSTPDVLIQLAQEGVKN 258 Query: 440 LLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVEA 267 +L VP+SFVS+H+ETL EID+ Y++ A + G+ P+L FI+ L V+E+ Sbjct: 259 ILMVPISFVSDHVETLYEIDILYKKQAKKLGM-RLTSCPSLNTQEQFITGLRQLVLES 315
>HEMH_MOUSE (P22315) Ferrochelatase, mitochondrial precursor (EC 4.99.1.1)| (Protoheme ferro-lyase) (Heme synthetase) Length = 420 Score = 92.8 bits (229), Expect = 7e-19 Identities = 53/129 (41%), Positives = 77/129 (59%), Gaps = 1/129 (0%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS 441 GDPY ++ + +ME+L G N + L +QS+VGPV WL P TDE + L ++G K+ Sbjct: 270 GDPYPQEVGATVHKVMEKL---GYPNPYRLVWQSKVGPVPWLGPQTDEAIKGLCERGRKN 326 Query: 440 LLAVPVSFVSEHIETLEEIDMEYRE-LALESGIENWGRVPALGCTSSFISDLADAVVEAL 264 +L VP++F S+HIETL E+D+EY + LA + G EN R +L F LAD V + Sbjct: 327 ILLVPIAFTSDHIETLYELDIEYSQVLAQKCGAENIRRAESLNGNPLFSKALADLVHSHI 386 Query: 263 PSASAMATR 237 S +T+ Sbjct: 387 QSNKLCSTQ 395
>HEMH_CAUCR (P57777) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 347 Score = 92.4 bits (228), Expect = 9e-19 Identities = 52/122 (42%), Positives = 74/122 (60%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS 441 GDPY+ Q+E A + L + + T+ YQSRVGP++W+ P TD+ + G + K Sbjct: 203 GDPYQKQVEATAAAVAAHLPPQ---IEWTVCYQSRVGPLKWIGPSTDDEIRRAGGED-KG 258 Query: 440 LLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVEALP 261 ++ P++FVSEH+ETL E+D EY ELA E G + RV ALG FI LA AV +++ Sbjct: 259 VMITPIAFVSEHVETLVELDHEYAELAEEVGAAPYLRVSALGTAPEFIDGLAKAVRDSVG 318 Query: 260 SA 255 A Sbjct: 319 KA 320
>HEMH_PANTR (Q3YA36) Ferrochelatase, mitochondrial precursor (EC 4.99.1.1)| (Protoheme ferro-lyase) (Heme synthetase) Length = 423 Score = 92.4 bits (228), Expect = 9e-19 Identities = 50/116 (43%), Positives = 72/116 (62%), Gaps = 1/116 (0%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS 441 GDPY ++ + +ME L+ N + L +QS+VGP+ WL P TDE + L ++G K+ Sbjct: 273 GDPYPQEVSATVQKVMERLEY---CNPYRLVWQSKVGPMPWLGPQTDESIKGLCERGRKN 329 Query: 440 LLAVPVSFVSEHIETLEEIDMEYRE-LALESGIENWGRVPALGCTSSFISDLADAV 276 +L VP++F S+HIETL E+D+EY + LA E G+EN R +L F LAD V Sbjct: 330 ILLVPIAFTSDHIETLYELDIEYSQVLAKECGVENIRRAESLNGNPLFSKALADLV 385
>HEMH_HUMAN (P22830) Ferrochelatase, mitochondrial precursor (EC 4.99.1.1)| (Protoheme ferro-lyase) (Heme synthetase) Length = 423 Score = 92.4 bits (228), Expect = 9e-19 Identities = 50/116 (43%), Positives = 72/116 (62%), Gaps = 1/116 (0%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS 441 GDPY ++ + +ME L+ N + L +QS+VGP+ WL P TDE + L ++G K+ Sbjct: 273 GDPYPQEVSATVQKVMERLEY---CNPYRLVWQSKVGPMPWLGPQTDESIKGLCERGRKN 329 Query: 440 LLAVPVSFVSEHIETLEEIDMEYRE-LALESGIENWGRVPALGCTSSFISDLADAV 276 +L VP++F S+HIETL E+D+EY + LA E G+EN R +L F LAD V Sbjct: 330 ILLVPIAFTSDHIETLYELDIEYSQVLAKECGVENIRRAESLNGNPLFSKALADLV 385
>HEMH_DROME (Q9V9S8) Ferrochelatase, mitochondrial precursor (EC 4.99.1.1)| (Protoheme ferro-lyase) (Heme synthetase) Length = 384 Score = 92.0 bits (227), Expect = 1e-18 Identities = 50/126 (39%), Positives = 77/126 (61%), Gaps = 1/126 (0%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS 441 GD Y ++ + ++M+EL G N ++LA+QS+VGP+ WL P TD+ + ++G+K+ Sbjct: 233 GDAYPSEIGASVHMVMQEL---GQTNPYSLAWQSKVGPLPWLAPATDDAIKGYVKQGLKN 289 Query: 440 LLAVPVSFVSEHIETLEEIDMEY-RELALESGIENWGRVPALGCTSSFISDLADAVVEAL 264 + VP++FV+EHIETL E+D+EY ELA E G+E R FI L + V + L Sbjct: 290 FILVPIAFVNEHIETLHELDIEYCDELAKEVGVEEIRRAATPNDHPLFIDALTNVVADHL 349 Query: 263 PSASAM 246 S A+ Sbjct: 350 KSQQAV 355
>HEMH_LEPBI (Q8GCV0) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 362 Score = 90.9 bits (224), Expect = 3e-18 Identities = 47/118 (39%), Positives = 76/118 (64%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS 441 GD Y +++E + I +EL G ++YQS+VGP +W +P T +++ L ++G K Sbjct: 222 GDRYMEEVELSVKGIADELSKFGFNGGVHISYQSKVGPAKWTEPSTIQMISSLAKQG-KH 280 Query: 440 LLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVEA 267 + P+SFVS+HIETLEEI ++++L E G +++ R+PALG SFI LA+ V+ + Sbjct: 281 IAVYPISFVSDHIETLEEIGEQFKDLTWEMGGKSFVRIPALGIYPSFIQFLAEKVMHS 338
>HEMH_WOLPM (Q73FY6) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 315 Score = 85.1 bits (209), Expect = 1e-16 Identities = 48/116 (41%), Positives = 70/116 (60%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS 441 GDPY Q+E + LI+E+L D ++ YQS++GPV+WL+P T+ L+ GV Sbjct: 203 GDPYASQVERSVELIVEKLAINNL--DWSICYQSKIGPVKWLEPSTESELLRAKADGVPV 260 Query: 440 LLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVV 273 +L+ P+SFVSEH ETL E+D+EY+ + + + RVP L FI LAD + Sbjct: 261 VLS-PISFVSEHSETLVELDIEYKAIIKDG---YYFRVPTLSTDPLFIKCLADLCI 312
>HEMH_SCHPO (O59786) Ferrochelatase, mitochondrial precursor (EC 4.99.1.1)| (Protoheme ferro-lyase) (Heme synthetase) Length = 384 Score = 83.2 bits (204), Expect = 6e-16 Identities = 45/119 (37%), Positives = 73/119 (61%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS 441 GDPY ++ +M+ L + N A+QS+VGP+ W+ P TD V+ +LG +G K+ Sbjct: 238 GDPYVYEIAATSQAVMKRLNYK---NKFVNAWQSKVGPLPWMSPATDFVIEQLGNRGQKN 294 Query: 440 LLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVEAL 264 ++ VP++F S+HIETL+E++ +Y E A + GI RV ++ + + I +AD V E L Sbjct: 295 MILVPIAFTSDHIETLKELE-DYIEDAKQKGITGVKRVSSINGSMTAIQGMADLVAEHL 352
>HEMH_BRUSU (P0A3D7) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 352 Score = 80.9 bits (198), Expect = 3e-15 Identities = 45/102 (44%), Positives = 62/102 (60%), Gaps = 1/102 (0%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLA-YQSRVGPVQWLKPYTDEVLVELGQKGVK 444 GDPYR Q + L+ E L G D A +QSR GP +WL+PYTDE + EL + GVK Sbjct: 232 GDPYRQQCLETTRLLRERL---GLGEDEMRATFQSRFGPEEWLQPYTDETVKELAKNGVK 288 Query: 443 SLLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPAL 318 S+ + FV++ +ET++EI E E LE+G EN+ +P L Sbjct: 289 SVAVLNPGFVADCLETVDEIGNEAAEEFLENGGENFSHIPCL 330
>HEMH_BRUME (P0A3D6) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 352 Score = 80.9 bits (198), Expect = 3e-15 Identities = 45/102 (44%), Positives = 62/102 (60%), Gaps = 1/102 (0%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLA-YQSRVGPVQWLKPYTDEVLVELGQKGVK 444 GDPYR Q + L+ E L G D A +QSR GP +WL+PYTDE + EL + GVK Sbjct: 232 GDPYRQQCLETTRLLRERL---GLGEDEMRATFQSRFGPEEWLQPYTDETVKELAKNGVK 288 Query: 443 SLLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPAL 318 S+ + FV++ +ET++EI E E LE+G EN+ +P L Sbjct: 289 SVAVLNPGFVADCLETVDEIGNEAAEEFLENGGENFSHIPCL 330
>HEMH_BRUAB (P0A3D8) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 352 Score = 78.6 bits (192), Expect = 1e-14 Identities = 44/102 (43%), Positives = 61/102 (59%), Gaps = 1/102 (0%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLA-YQSRVGPVQWLKPYTDEVLVELGQKGVK 444 GDPYR Q + L+ E L G D A +QSR GP +WL+PYTDE + EL + GVK Sbjct: 232 GDPYRQQCLETTRLLRERL---GLGEDEMRATFQSRFGPEEWLQPYTDETVKELAKNGVK 288 Query: 443 SLLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPAL 318 + + FV++ +ET++EI E E LE+G EN+ +P L Sbjct: 289 LVAVLNPGFVADCLETVDEIGNEAAEEFLENGGENFSHIPCL 330
>HEMH_BURPS (Q63R43) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 367 Score = 77.4 bits (189), Expect = 3e-14 Identities = 47/133 (35%), Positives = 70/133 (52%), Gaps = 3/133 (2%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS 441 GDPY DQ + AL+M L T + + +QSR G +WL+PYT L ELG GV+ Sbjct: 236 GDPYHDQCQQTAALLMSALGL--TTFECRVTFQSRFGKAEWLQPYTAPTLKELGAAGVRR 293 Query: 440 LLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVEAL- 264 F ++ +ET+EEI +E R+ + G + + R+P L + ++I+ L + E L Sbjct: 294 ADVFCPGFTADCLETIEEIGIEVRDEFVHGGGKEFHRIPCLNASPAWIAALGEIAAENLQ 353 Query: 263 --PSASAMATRKV 231 P AMA V Sbjct: 354 GWPVRVAMAPEAV 366
>HEMH_BURMA (Q62HD1) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 367 Score = 77.4 bits (189), Expect = 3e-14 Identities = 47/133 (35%), Positives = 70/133 (52%), Gaps = 3/133 (2%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS 441 GDPY DQ + AL+M L T + + +QSR G +WL+PYT L ELG GV+ Sbjct: 236 GDPYHDQCQQTAALLMSALGL--TTFECRVTFQSRFGKAEWLQPYTAPTLKELGAAGVRR 293 Query: 440 LLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVEAL- 264 F ++ +ET+EEI +E R+ + G + + R+P L + ++I+ L + E L Sbjct: 294 ADVFCPGFTADCLETIEEIGIEVRDEFVHGGGKEFHRIPCLNASPAWIAALGEIAAENLQ 353 Query: 263 --PSASAMATRKV 231 P AMA V Sbjct: 354 GWPVRVAMAPEAV 366
>HEMH_ACIAD (Q6F7N0) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 340 Score = 77.4 bits (189), Expect = 3e-14 Identities = 38/101 (37%), Positives = 65/101 (64%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS 441 GDPY D+ + L+ ++L T +D +++QSR G +W+KPYTDE+L G+KS Sbjct: 212 GDPYADRCRETARLVAKQLGL--TPDDWAISFQSRFGKQEWVKPYTDELLTTWAANGIKS 269 Query: 440 LLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPAL 318 + + +F ++ +ETLEE++++ EL LE+G ++ +PAL Sbjct: 270 VQILSPAFSADCLETLEELEIQNAELFLEAGGTSYQYIPAL 310
>HEMH_RHOPA (Q6NBF3) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 345 Score = 74.3 bits (181), Expect = 3e-13 Identities = 43/120 (35%), Positives = 66/120 (55%), Gaps = 1/120 (0%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTL-AYQSRVGPVQWLKPYTDEVLVELGQKGVK 444 GDPY+ Q C+A + + G +D L +QSR G QWL+PYTD+ + L +KGV+ Sbjct: 225 GDPYQAQ---CVATVEALRERMGVADDKLLLTFQSRFGFDQWLQPYTDKTIEALARKGVR 281 Query: 443 SLLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVEAL 264 L V F ++ +ETLEEI E E+ +E G E + +P L + + + + V+ L Sbjct: 282 KLAVVMPGFSADCLETLEEIAQENAEIFMEHGGEEFTAIPCLNDSDAGVQVIRQLVLREL 341
>HEMH_STRMU (Q8CWW4) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 319 Score = 73.6 bits (179), Expect = 5e-13 Identities = 35/90 (38%), Positives = 58/90 (64%) Frame = -1 Query: 533 LAYQSRVGPVQWLKPYTDEVLVELGQKGVKSLLAVPVSFVSEHIETLEEIDMEYRELALE 354 ++YQSR GP +W +PYTDE L++L ++G K L + F ++ +ETLEEID+ R+ + Sbjct: 230 VSYQSRFGPEEWTRPYTDETLIQLPKQGKKKLAVICPGFAADCLETLEEIDITNRKHFMA 289 Query: 353 SGIENWGRVPALGCTSSFISDLADAVVEAL 264 +G + + +PAL + + I LA+ + E L Sbjct: 290 AGGQAYRYIPALNASPAHIQLLAELISERL 319
>HEMH_BORPE (Q7VVX8) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 362 Score = 72.4 bits (176), Expect = 1e-12 Identities = 43/119 (36%), Positives = 63/119 (52%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS 441 GDPY D L+ E L R ++ + +QSR G +WL+PYT+ L EL ++GV Sbjct: 238 GDPYYRDCLDTARLLRERLGLRE--DEVEVTFQSRFGSARWLEPYTEPTLAELARQGVTE 295 Query: 440 LLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVEAL 264 + V FV++ +ETLEEI E R+ + +G + +PAL +I L D V L Sbjct: 296 VDVVCPGFVADCLETLEEISQECRDAFVAAGGRQFRYIPALNDCPPWIEGLTDLVERQL 354
>HEMH_BORPA (Q7W515) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 362 Score = 72.4 bits (176), Expect = 1e-12 Identities = 43/119 (36%), Positives = 63/119 (52%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS 441 GDPY D L+ E L R ++ + +QSR G +WL+PYT+ L EL ++GV Sbjct: 238 GDPYYRDCLDTARLLRERLGLRE--DEVEVTFQSRFGSARWLEPYTEPTLAELARQGVTE 295 Query: 440 LLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVEAL 264 + V FV++ +ETLEEI E R+ + +G + +PAL +I L D V L Sbjct: 296 VDVVCPGFVADCLETLEEISQECRDAFVAAGGRQFRYIPALNDCPPWIEGLTDLVERQL 354
>HEMH_BORBR (Q7WGI0) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 362 Score = 72.4 bits (176), Expect = 1e-12 Identities = 43/119 (36%), Positives = 63/119 (52%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS 441 GDPY D L+ E L R ++ + +QSR G +WL+PYT+ L EL ++GV Sbjct: 238 GDPYYRDCLDTARLLRERLGLRE--DEVEVTFQSRFGSARWLEPYTEPTLAELARQGVTE 295 Query: 440 LLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVEAL 264 + V FV++ +ETLEEI E R+ + +G + +PAL +I L D V L Sbjct: 296 VDVVCPGFVADCLETLEEISQECRDAFVAAGGRQFRYIPALNDCPPWIEGLTDLVERQL 354
>HEMH_CHRVO (Q7NV65) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 364 Score = 72.0 bits (175), Expect = 1e-12 Identities = 44/115 (38%), Positives = 62/115 (53%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS 441 GDPY + + L+ E L+ R + + +++QSR G +WLKPYT EVL LG+ Sbjct: 223 GDPYHCECQKTGRLLAEALQLRP--DQYVISFQSRFGRTEWLKPYTSEVLEALGKAKTAR 280 Query: 440 LLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAV 276 + V FV + +ETLEEI ME +E L G + +P L +IS LA V Sbjct: 281 VDVVCPGFVGDCLETLEEIAMEGKETFLSHGGGEFRYIPCLNEDPQWISSLAGIV 335
>HEMH_AGRT5 (Q8U9F7) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 344 Score = 72.0 bits (175), Expect = 1e-12 Identities = 40/115 (34%), Positives = 64/115 (55%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS 441 GDPY + L+ E L T + + +QSR GP +WL+PYTD+ + +L +G+K Sbjct: 224 GDPYYCHCQKTARLLREALGR--TEKNFMITFQSRFGPEEWLQPYTDKTVEKLASEGIKR 281 Query: 440 LLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAV 276 + + FVS+ +ETLEEI E E+ L +G E + +P L ++ ++ L V Sbjct: 282 IAVMNPGFVSDCLETLEEIAGEAGEIFLHNGGEKFTHIPCLNDSTEGMNVLEKVV 336
>HEMH_PASMU (P57874) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 326 Score = 71.6 bits (174), Expect = 2e-12 Identities = 37/123 (30%), Positives = 68/123 (55%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS 441 GD YR+ + + +++ L T N L++QSR G +WL+PYTD+ L + + ++ Sbjct: 205 GDYYREHCKQTVLAVIDRLGL--TENQWGLSFQSRFGKEEWLQPYTDQFLAQAPSQNIQK 262 Query: 440 LLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVEALP 261 + + F ++ +ETLEEI+ E +E+ L +G ++ +PAL I +A+ ++ L Sbjct: 263 MAVICPGFAADCLETLEEIEEENKEIFLANGGISYRYIPALNARPEHIQMMANLILNKLN 322 Query: 260 SAS 252 S Sbjct: 323 QTS 325
>HEMH_CHLCV (Q824K8) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 318 Score = 70.9 bits (172), Expect = 3e-12 Identities = 45/120 (37%), Positives = 66/120 (55%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS 441 GDPY Q E I E L + T L YQS+ GP +WL P T ++ L + K Sbjct: 196 GDPYNMQCEKSFRAISERLPNIET----HLCYQSKFGPGKWLSPSTKDLCATL-KTDKKH 250 Query: 440 LLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVEALP 261 +L VP F S+HIETL EI+ EY + ++ G + RVPA+ +S ++ LA ++++ P Sbjct: 251 VLIVPFGFTSDHIETLYEIEKEYIAVLIDKGYQAL-RVPAIYQSSQWVESLA-TIIQSTP 308
>HEMH_CHLTR (O84492) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 314 Score = 70.5 bits (171), Expect = 4e-12 Identities = 45/125 (36%), Positives = 69/125 (55%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS 441 GDPY Q + + EL+ + +A+QS+ G +WL P T EV L K + Sbjct: 194 GDPYAQQCQASFEALRGELEGK-------IAFQSKFGIGKWLDPSTQEVCQSLRTKK-RY 245 Query: 440 LLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVEALP 261 ++ VP FVS+HIETL EID Y + L+ G R+PA+ +S ++S LA A+V + P Sbjct: 246 IVIVPFGFVSDHIETLHEIDHLYVPILLQKGY-RVVRIPAINASSRWVSSLA-AIVRSSP 303 Query: 260 SASAM 246 +++ Sbjct: 304 QETSL 308
>HEMH_VIBPA (Q87RH3) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 320 Score = 70.1 bits (170), Expect = 5e-12 Identities = 44/116 (37%), Positives = 64/116 (55%), Gaps = 1/116 (0%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHT-LAYQSRVGPVQWLKPYTDEVLVELGQKGVK 444 GD Y E L+ E L G +D +AYQSR G +WL+PYTD+ L + KGVK Sbjct: 204 GDIYPQHCEATTRLLGEAL---GLSSDQIGMAYQSRFGREEWLQPYTDKTLETITSKGVK 260 Query: 443 SLLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAV 276 + + +F S+ +ETLEEI E +E+ +E+G E + +P L I +A+ V Sbjct: 261 KIDIMTPAFSSDCLETLEEIAGENKEIFMEAGGEQFHYIPCLNDDDMHIDMMAELV 316
>HEMH_PSEAE (Q9HVD7) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 340 Score = 69.7 bits (169), Expect = 7e-12 Identities = 36/85 (42%), Positives = 57/85 (67%) Frame = -1 Query: 536 TLAYQSRVGPVQWLKPYTDEVLVELGQKGVKSLLAVPVSFVSEHIETLEEIDMEYRELAL 357 ++++QSR+G +W++PYTD L EL Q+GVK LL + +FV++ IETLEEI M RE + Sbjct: 247 SVSFQSRLGRAKWIEPYTDAKLDELVQRGVKRLLVMCPAFVADCIETLEEIGMRGREQFI 306 Query: 356 ESGIENWGRVPALGCTSSFISDLAD 282 +G E+ +P L +++ LA+ Sbjct: 307 SAGGEDLVLIPCLNDHPAWVGALAE 331
>HEMH_LEGPL (Q5WZB4) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 331 Score = 69.3 bits (168), Expect = 9e-12 Identities = 42/114 (36%), Positives = 65/114 (57%) Frame = -1 Query: 611 YRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKSLLA 432 YR Q L+ +EL+ GT + +T A+QSR+G W+KPYTDE+ EL KG+K+++ Sbjct: 218 YRAQCYQTSLLLAKELQL-GT-HQYTTAFQSRLGKTPWIKPYTDEIFAELISKGIKNIVV 275 Query: 431 VPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVE 270 SFV++ +ETLEEI + +E + G E + P + +I + V E Sbjct: 276 SCPSFVADCLETLEEIGIRAKEQWEKLGGEQFILTPCMNDHPEWIKAIQSIVNE 329
>HEMH_LEGPH (Q5ZYE7) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 331 Score = 69.3 bits (168), Expect = 9e-12 Identities = 42/114 (36%), Positives = 65/114 (57%) Frame = -1 Query: 611 YRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKSLLA 432 YR Q L+ +EL+ GT + +T A+QSR+G W+KPYTDE+ EL KG+K+++ Sbjct: 218 YRAQCYQTSLLLAKELQL-GT-HQYTTAFQSRLGKTPWIKPYTDEIFAELISKGIKNIVV 275 Query: 431 VPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVE 270 SFV++ +ETLEEI + +E + G E + P + +I + V E Sbjct: 276 SCPSFVADCLETLEEIGIRAKEQWEKLGGEQFILTPCMNDHPEWIKAIQSIVNE 329
>HEMH_LEGPA (Q5X7W3) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 331 Score = 69.3 bits (168), Expect = 9e-12 Identities = 42/116 (36%), Positives = 66/116 (56%) Frame = -1 Query: 611 YRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKSLLA 432 YR Q L+ +EL+ GT + +T A+QSR+G W+KPYTDE+ EL KG+K+++ Sbjct: 218 YRAQCYQTSLLLAKELQL-GT-HQYTTAFQSRLGKTPWIKPYTDEIFAELISKGIKNIVV 275 Query: 431 VPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVEAL 264 SFV++ +ETLEEI + +E + G E + P + +I + V E + Sbjct: 276 SCPSFVADCLETLEEIGIRAKEQWEKLGGEQFILTPCMNDHPEWIKAIHSIVNEQI 331
>HEMH_IDILO (Q5QVZ8) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 364 Score = 68.9 bits (167), Expect = 1e-11 Identities = 45/116 (38%), Positives = 60/116 (51%), Gaps = 1/116 (0%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLA-YQSRVGPVQWLKPYTDEVLVELGQKGVK 444 GDPY + L+ E L G D L +QSR G +WL+PYTD + L KGVK Sbjct: 220 GDPYHCECYKTSRLLAERL---GLGKDEYLTTFQSRFGREEWLQPYTDMTMKALPGKGVK 276 Query: 443 SLLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAV 276 S+ F S+ +ET+EEI E RE +ESG E + + AL S I L+ + Sbjct: 277 SVQVFCPGFSSDCLETVEEIGEENREYFMESGGERYEYISALNAESGHIDALSQLI 332
>HEMH_RHIME (Q92M52) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 339 Score = 68.2 bits (165), Expect = 2e-11 Identities = 39/102 (38%), Positives = 57/102 (55%), Gaps = 1/102 (0%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHT-LAYQSRVGPVQWLKPYTDEVLVELGQKGVK 444 GDPY Q + L+ E+L G D + +QSR GP +WL+PYTD + L ++GVK Sbjct: 219 GDPYYCQCQKTARLLREKL---GWPQDRLQVTFQSRFGPEEWLQPYTDATVERLAKEGVK 275 Query: 443 SLLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPAL 318 + + FVS+ +ETLEEI + E +G E + +P L Sbjct: 276 RIAVINPGFVSDCLETLEEIAGQAAESFHHNGGEKFAHIPCL 317
>HEMH_RHOCA (Q59735) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 351 Score = 67.8 bits (164), Expect = 2e-11 Identities = 44/119 (36%), Positives = 64/119 (53%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS 441 GDPY Q + L+ E L D T +QS G +WL+PYT E +V+L + G K+ Sbjct: 230 GDPYHCQCQKTSRLLRERLGWGPDSIDTT--FQSVFGTEEWLRPYTVEHVVQLAEAGKKN 287 Query: 440 LLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVEAL 264 + + +F ++ IETLEEI+ E RE +G E++ VP L I+ L + V E L Sbjct: 288 IAVISPAFSADCIETLEEINGEIREAFEHAGGESFTYVPCLNDDDLHIAALLEVVEENL 346
>HEMH_ENTFA (Q833G5) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 313 Score = 67.4 bits (163), Expect = 3e-11 Identities = 38/93 (40%), Positives = 56/93 (60%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS 441 GD Y + LIM++L G + + YQS+ GP +WLKP TD+ L +L KG+K+ Sbjct: 201 GDNYPKECTKTTKLIMDKL---GDIRYYQ-TYQSKFGPSEWLKPATDDTLKKLPSKGIKN 256 Query: 440 LLAVPVSFVSEHIETLEEIDMEYRELALESGIE 342 +L V FV + +ET+EE++ E R LE+G E Sbjct: 257 ILIVAPGFVVDCLETIEELEHENRNYFLENGGE 289
>HEMH_DEIRA (Q9RV98) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 316 Score = 67.4 bits (163), Expect = 3e-11 Identities = 41/116 (35%), Positives = 64/116 (55%), Gaps = 1/116 (0%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRV-GPVQWLKPYTDEVLVELGQKGVK 444 GDPY DQ+ + L+ + T + +YQS P WL P DE L +L ++G+K Sbjct: 196 GDPYADQLHETARLVAAQAGL--TDEQWSWSYQSAGRSPEPWLGPQLDEHLRDLNEQGIK 253 Query: 443 SLLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAV 276 ++++ + FVS+H+E L +ID+ +E+A E G+ R PAL FI LA + Sbjct: 254 KVVSIAIGFVSDHVEILFDIDIAAQEVAHELGM-TLVRPPALNTDPLFIGTLASVI 308
>HEMH_LEIXX (Q6AHF2) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 389 Score = 67.0 bits (162), Expect = 4e-11 Identities = 40/108 (37%), Positives = 65/108 (60%), Gaps = 2/108 (1%) Frame = -1 Query: 587 IALIMEELKSRGTLNDHTLAYQSRVGP--VQWLKPYTDEVLVELGQKGVKSLLAVPVSFV 414 +A I+ + GT+ L YQSR GP + WL+P ++ + EL + GVK+++ VP+ FV Sbjct: 240 VAEIVSHEATGGTIG-WDLVYQSRSGPPSMPWLEPDINDRIAELPELGVKAIIIVPLGFV 298 Query: 413 SEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVE 270 S+H+E L ++D E E + E+G+ RVP G + ++ L D V+E Sbjct: 299 SDHMEVLWDLDTEAMESSEENGLLA-VRVPTPGTHAKYVKGLVDLVLE 345 Score = 30.8 bits (68), Expect = 3.4 Identities = 29/94 (30%), Positives = 40/94 (42%), Gaps = 3/94 (3%) Frame = -1 Query: 614 PYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKSLL 435 P DQ A + EL SRG D + + +R W PY + L E Q+G L+ Sbjct: 71 PINDQNRALKAALEAELASRGI--DLPVLWGNR----NW-DPYLADALTEADQRGFTKLI 123 Query: 434 AVPVSFVSEHI---ETLEEIDMEYRELALESGIE 342 AV S S + + E+ RE LE I+ Sbjct: 124 AVATSAYSSYSSCRQYREDFARALRETGLEGRIQ 157
>HEMH_PROFR (P72183) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 352 Score = 67.0 bits (162), Expect = 4e-11 Identities = 41/121 (33%), Positives = 65/121 (53%), Gaps = 2/121 (1%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQ--WLKPYTDEVLVELGQKGV 447 G+ Y Q I +M EL + G LAYQSR G + WL+P ++V+ L +GV Sbjct: 192 GNAYIPQHLALIDAVMAELAALGLRPSWELAYQSRSGSPRTPWLEPDINDVITRLAGEGV 251 Query: 446 KSLLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVEA 267 + ++ P+ F+++H+E + ++D E A E + + RV +G FI LAD +V A Sbjct: 252 RDVICSPIGFLTDHMEVVWDLDTEAAATAAEHSMA-FTRVATVGTLPVFIEGLADLIVAA 310 Query: 266 L 264 L Sbjct: 311 L 311
>HEMH1_SHEON (Q8EFF4) Ferrochelatase 1 (EC 4.99.1.1) (Protoheme ferro-lyase 1)| (Heme synthetase 1) Length = 348 Score = 67.0 bits (162), Expect = 4e-11 Identities = 37/101 (36%), Positives = 58/101 (57%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS 441 GDPY +Q L+ + L T + +QSR G +WL PY DE+L +L ++GVKS Sbjct: 225 GDPYPEQCRTTAKLLAQALGL--TDGQWQVCFQSRFGKEEWLTPYADELLADLPRQGVKS 282 Query: 440 LLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPAL 318 + + +F ++ +ETLEEI + +E L +G E + +P L Sbjct: 283 VDVICPAFATDCLETLEEISIGAKETFLHAGGEAYHFIPCL 323
>HEMH_SHIFL (Q83SE5) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 320 Score = 66.2 bits (160), Expect = 7e-11 Identities = 35/86 (40%), Positives = 51/86 (59%) Frame = -1 Query: 533 LAYQSRVGPVQWLKPYTDEVLVELGQKGVKSLLAVPVSFVSEHIETLEEIDMEYRELALE 354 + +QSR G WL PYTDE L LG+KGV + + F ++ +ETLEEI + RE+ L Sbjct: 231 MTFQSRFGREPWLMPYTDETLKMLGEKGVGHIQVMCPGFAADCLETLEEIAEQNREVFLG 290 Query: 353 SGIENWGRVPALGCTSSFISDLADAV 276 +G + + +PAL T I +A+ V Sbjct: 291 AGGKKYEYIPALNATPEHIEMMANLV 316
>HEMH_ECOLI (P23871) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 320 Score = 66.2 bits (160), Expect = 7e-11 Identities = 35/86 (40%), Positives = 51/86 (59%) Frame = -1 Query: 533 LAYQSRVGPVQWLKPYTDEVLVELGQKGVKSLLAVPVSFVSEHIETLEEIDMEYRELALE 354 + +QSR G WL PYTDE L LG+KGV + + F ++ +ETLEEI + RE+ L Sbjct: 231 MTFQSRFGREPWLMPYTDETLKMLGEKGVGHIQVMCPGFAADCLETLEEIAEQNREVFLG 290 Query: 353 SGIENWGRVPALGCTSSFISDLADAV 276 +G + + +PAL T I +A+ V Sbjct: 291 AGGKKYEYIPALNATPEHIEMMANLV 316
>HEMH_ECOL6 (Q8FK83) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 320 Score = 66.2 bits (160), Expect = 7e-11 Identities = 35/86 (40%), Positives = 51/86 (59%) Frame = -1 Query: 533 LAYQSRVGPVQWLKPYTDEVLVELGQKGVKSLLAVPVSFVSEHIETLEEIDMEYRELALE 354 + +QSR G WL PYTDE L LG+KGV + + F ++ +ETLEEI + RE+ L Sbjct: 231 MTFQSRFGREPWLMPYTDETLKMLGEKGVGHIQVMCPGFAADCLETLEEIAEQNREVFLG 290 Query: 353 SGIENWGRVPALGCTSSFISDLADAV 276 +G + + +PAL T I +A+ V Sbjct: 291 AGGKKYEYIPALNATPEHIEMMANLV 316
>HEMH_ECO57 (Q8XD39) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 320 Score = 66.2 bits (160), Expect = 7e-11 Identities = 35/86 (40%), Positives = 51/86 (59%) Frame = -1 Query: 533 LAYQSRVGPVQWLKPYTDEVLVELGQKGVKSLLAVPVSFVSEHIETLEEIDMEYRELALE 354 + +QSR G WL PYTDE L LG+KGV + + F ++ +ETLEEI + RE+ L Sbjct: 231 MTFQSRFGREPWLMPYTDETLKMLGEKGVGHIQVMCPGFAADCLETLEEIAEQNREVFLG 290 Query: 353 SGIENWGRVPALGCTSSFISDLADAV 276 +G + + +PAL T I +A+ V Sbjct: 291 AGGKKYEYIPALNATPEHIEMMANLV 316
>HEMH_MANSM (Q65SV7) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 323 Score = 66.2 bits (160), Expect = 7e-11 Identities = 38/119 (31%), Positives = 64/119 (53%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS 441 GD YR Q E ++++L + L +QSR G WL+PYTD+ L Q+G+ Sbjct: 205 GDFYRPQCEQTAQAVVQKLGLKK--EQWRLCFQSRFGSEPWLQPYTDKFLETAAQQGITK 262 Query: 440 LLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVEAL 264 L + F ++ +ETLEEI E + + L G E++ +PAL + I+ L + +++ + Sbjct: 263 LAVICPGFSADCLETLEEIKEENKRIFLAYGGESYHYIPALNDSPEHIACLGNLLLKRM 321
>HEMH_HAEIN (P43868) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 323 Score = 66.2 bits (160), Expect = 7e-11 Identities = 36/119 (30%), Positives = 63/119 (52%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS 441 GD YR+ + ++ +L T N + +QSR G +WL+PYTD+ L + ++ Sbjct: 206 GDYYREHCKQTTIAVVNKLGL--TENQWRMTFQSRFGREEWLQPYTDKFLESAAAQNIQK 263 Query: 440 LLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVEAL 264 + + F + +ET+EEID E RE L +G +++ +PAL + I + ++E L Sbjct: 264 IAVICPGFSVDCLETIEEIDEENRENFLNNGGQSYQYIPALNVEHAHIEMMGKLILEKL 322
>HEMH_YEAST (P16622) Ferrochelatase, mitochondrial precursor (EC 4.99.1.1)| (Protoheme ferro-lyase) (Heme synthetase) Length = 393 Score = 66.2 bits (160), Expect = 7e-11 Identities = 45/127 (35%), Positives = 67/127 (52%), Gaps = 6/127 (4%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS 441 GD Y ++ + IM++LK + N + L +QS+VGP WL T E+ LG K V Sbjct: 245 GDAYPAEVAATVYNIMQKLKFK---NPYRLVWQSQVGPKPWLGAQTAEIAEFLGPK-VDG 300 Query: 440 LLAVPVSFVSEHIETLEEIDM------EYRELALESGIENWGRVPALGCTSSFISDLADA 279 L+ +P++F S+HIETL EID+ EY+ + + R +L +FI +AD Sbjct: 301 LMFIPIAFTSDHIETLHEIDLGVIGESEYK--------DKFKRCESLNGNQTFIEGMADL 352 Query: 278 VVEALPS 258 V L S Sbjct: 353 VKSHLQS 359
>HEMH_SALTY (P37408) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 320 Score = 65.9 bits (159), Expect = 9e-11 Identities = 33/79 (41%), Positives = 47/79 (59%) Frame = -1 Query: 533 LAYQSRVGPVQWLKPYTDEVLVELGQKGVKSLLAVPVSFVSEHIETLEEIDMEYRELALE 354 + +QSR G WL PYTDE L LG+KG + + F ++ +ETLEEI + RE+ LE Sbjct: 231 MTFQSRFGREPWLTPYTDETLKMLGEKGTGHIQVMCPGFAADCLETLEEIAEQNREIFLE 290 Query: 353 SGIENWGRVPALGCTSSFI 297 +G + + +PAL T I Sbjct: 291 AGGKKYAYIPALNATPEHI 309
>HEMH_LACPL (Q88XC3) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 324 Score = 65.9 bits (159), Expect = 9e-11 Identities = 40/131 (30%), Positives = 68/131 (51%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS 441 GDPY+ + E ++ E + + AYQS+ GP+ WLKPY L++L + G ++ Sbjct: 194 GDPYQRECEATTKAVLAE-RPELPADKVITAYQSKFGPMPWLKPYLKNELMQLVELGKRN 252 Query: 440 LLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVEALP 261 +L V SFV + +ETLEE ++ + SG + + VP + + F LAD ++ Sbjct: 253 VLVVTPSFVVDCLETLEEDYVQNYQTFRASGGDRFDLVPPMNKDTGFSQFLADLAIQKQE 312 Query: 260 SASAMATRKVK 228 +++ T K Sbjct: 313 ASNHAITSSSK 323
>HEMH_HELPY (P56107) Probable ferrochelatase (EC 4.99.1.1) (Protoheme| ferro-lyase) (Heme synthetase) Length = 334 Score = 65.9 bits (159), Expect = 9e-11 Identities = 36/116 (31%), Positives = 69/116 (59%), Gaps = 1/116 (0%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGT-LNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVK 444 GD Y+ + E ++L+ E ++ + T + L+YQS++GP++WL+P T+E L+E +K Sbjct: 217 GDTYQQECEHHVSLLKELMQQKNTPFKEVLLSYQSKLGPMKWLEPSTEE-LIEKHRK--S 273 Query: 443 SLLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAV 276 ++ P++F ++ ETL E+DM+YR +A ++ + P L + F + + V Sbjct: 274 HIIIYPLAFTIDNSETLYELDMQYRLMAERLAVKEYLVCPCLNDSIEFAQFIIERV 329
>HEMH_VIBVY (Q7MMR4) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 319 Score = 65.5 bits (158), Expect = 1e-10 Identities = 36/86 (41%), Positives = 50/86 (58%) Frame = -1 Query: 527 YQSRVGPVQWLKPYTDEVLVELGQKGVKSLLAVPVSFVSEHIETLEEIDMEYRELALESG 348 YQSR G +WL+PYTD+ L L KG+KSL + +F + +ETLEEI + +E L +G Sbjct: 233 YQSRFGREEWLQPYTDKTLESLPAKGIKSLDVITPAFSVDCLETLEEISEQGQESFLHAG 292 Query: 347 IENWGRVPALGCTSSFISDLADAVVE 270 E + +P L S I +A V E Sbjct: 293 GEQYRFIPCLNDAPSHIEMMARLVTE 318
>HEMH_VIBVU (Q8DFM2) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 319 Score = 65.5 bits (158), Expect = 1e-10 Identities = 36/86 (41%), Positives = 50/86 (58%) Frame = -1 Query: 527 YQSRVGPVQWLKPYTDEVLVELGQKGVKSLLAVPVSFVSEHIETLEEIDMEYRELALESG 348 YQSR G +WL+PYTD+ L L KG+KSL + +F + +ETLEEI + +E L +G Sbjct: 233 YQSRFGREEWLQPYTDKTLESLPAKGIKSLDVITPAFSVDCLETLEEISEQGQESFLHAG 292 Query: 347 IENWGRVPALGCTSSFISDLADAVVE 270 E + +P L S I +A V E Sbjct: 293 GEQYRFIPCLNDAPSHIEMMARLVTE 318
>HEMH_BRAJA (P28602) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 345 Score = 65.5 bits (158), Expect = 1e-10 Identities = 39/103 (37%), Positives = 59/103 (57%), Gaps = 2/103 (1%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTL--AYQSRVGPVQWLKPYTDEVLVELGQKGV 447 GDPY+ E CIA E L+ R ++ L +QSR G +WL+PYTD+ + L ++GV Sbjct: 225 GDPYQ---EHCIATT-EALRRRLGVDASKLLLTFQSRFGNDEWLQPYTDKTMERLAKEGV 280 Query: 446 KSLLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPAL 318 + + V F ++ +ETLEEI E E+ +G E + +P L Sbjct: 281 RRIAVVTPGFAADCLETLEEIAQENAEIFKHNGGEQFSAIPCL 323
>HEMH_COXBU (Q83FA4) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 343 Score = 65.5 bits (158), Expect = 1e-10 Identities = 38/116 (32%), Positives = 65/116 (56%) Frame = -1 Query: 611 YRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKSLLA 432 YR Q + LI ++L T + +A+QSR+G +W++PYTD+ L+EL +KG+K L+ Sbjct: 227 YRAQCFETSRLIAKKLNL--TDQQYGVAFQSRLGRAKWIEPYTDKYLIELSKKGIKKLMV 284 Query: 431 VPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVEAL 264 V SF + +ETLEEI + + E +P+L +++ +A ++L Sbjct: 285 VCPSFPVDCLETLEEIGIRAQSQWQRLDGETLKLIPSLNAHPQWVNAIAKMAKKSL 340
>HEMH_CAMJE (Q9PI08) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 303 Score = 65.1 bits (157), Expect = 2e-10 Identities = 34/87 (39%), Positives = 52/87 (59%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS 441 GD Y + D + ++ E+LK ++ LAYQS++GPV+WL+P T +VL L K Sbjct: 195 GDLYEKHVNDHVEILKEKLKDH--FDEFILAYQSKLGPVKWLEPNTSDVLANLNDKA--- 249 Query: 440 LLAVPVSFVSEHIETLEEIDMEYRELA 360 L P+SF + ET+ E+ MEY+ L+ Sbjct: 250 -LIYPISFCIDCSETIFELGMEYKHLS 275
>HEMH_PSEPK (Q88PV4) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 338 Score = 65.1 bits (157), Expect = 2e-10 Identities = 43/116 (37%), Positives = 66/116 (56%), Gaps = 1/116 (0%) Frame = -1 Query: 611 YRDQMEDCIALIMEELKSRGTLNDH-TLAYQSRVGPVQWLKPYTDEVLVELGQKGVKSLL 435 YR Q C+A +S G + ++++QSR+G +W++PYT+ L EL + GVK LL Sbjct: 226 YRGQ---CLATAKAFAQSMGIPDGKWSVSFQSRLGRDKWIEPYTETRLDELAKAGVKKLL 282 Query: 434 AVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVEA 267 + +FV++ IETLEEI M E +E+G + VP L ++ LAD +A Sbjct: 283 VMCPAFVADCIETLEEIGMRGSEQFVEAGGQELVLVPCLNDHPEWVRVLADMCEKA 338
>HEMH_YEREN (P43413) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 322 Score = 65.1 bits (157), Expect = 2e-10 Identities = 41/116 (35%), Positives = 59/116 (50%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS 441 GD Y + ED + E+ + YQSR G WL PYTDE L L +GVK Sbjct: 204 GDDYPQRCEDTSRALRAEIALPA--EQIMMTYQSRFGREPWLTPYTDETLKSLPSQGVKH 261 Query: 440 LLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVV 273 + + F ++ +ETLEEI + RE+ + +G E + +PAL I DL + +V Sbjct: 262 IQLICPGFSADCLETLEEIKEQNREVFIHAGGEKFEYIPALNDDKGHI-DLLEQLV 316
>HEMH_CHLMU (Q9PJQ6) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 317 Score = 64.7 bits (156), Expect = 2e-10 Identities = 42/115 (36%), Positives = 62/115 (53%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS 441 GDPY Q +D ++ E ++ L++QS+ G +WL P T E+ L K + Sbjct: 194 GDPYAKQCQDSFNALIGE-------SEGVLSFQSKFGIGEWLVPSTKEICQSLCTKK-RY 245 Query: 440 LLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAV 276 ++ VP FVS+HIETL EID Y + L+ G RVPA+ + ++S LA V Sbjct: 246 IVVVPFGFVSDHIETLYEIDHLYVPMLLQRGY-RVVRVPAINTSDRWVSALASIV 299
>HEMH_HELPJ (Q9ZKD4) Probable ferrochelatase (EC 4.99.1.1) (Protoheme| ferro-lyase) (Heme synthetase) Length = 335 Score = 64.3 bits (155), Expect = 3e-10 Identities = 35/116 (30%), Positives = 69/116 (59%), Gaps = 1/116 (0%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGT-LNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVK 444 GD Y+ + E ++L+ E ++ + + L+YQS++GP++WL+P T+E L+E +K Sbjct: 217 GDTYQQECEHHVSLLKELMQQKNIPFKEVLLSYQSKLGPMKWLEPSTEE-LIEKHRK--S 273 Query: 443 SLLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAV 276 +++ P++F ++ ETL E+DM+YR +A ++ + P L + F + + V Sbjct: 274 NIIIYPLAFTIDNSETLYELDMQYRLMAERLAVKEYLVCPCLNDSIEFAKFIIELV 329
>HEMH_FRATT (Q5NFT3) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 333 Score = 64.3 bits (155), Expect = 3e-10 Identities = 36/119 (30%), Positives = 65/119 (54%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS 441 GDPY L+ EEL++ D L++QSR GP +WL+PYT L E ++ KS Sbjct: 212 GDPYYCHCYKTYRLVKEELQNEYPNIDFELSFQSRFGPKKWLEPYTTVKLEEFTKQN-KS 270 Query: 440 LLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVEAL 264 ++ + F ++ +ETLEE+ + +E ++ G + + +P L ++ + L + + E + Sbjct: 271 VVVIAPGFSADCLETLEELAISEKENFIKKGGKEFSLIPCLNDSNQHVDMLYNIIDEEI 329
>HEMH_LACLA (Q9CFB4) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 314 Score = 64.3 bits (155), Expect = 3e-10 Identities = 36/114 (31%), Positives = 66/114 (57%) Frame = -1 Query: 617 DPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKSL 438 D Y +Q ++ L++ +L R +HT YQS+ GP +WL+P T + + EL ++ K + Sbjct: 198 DAYEEQCKETTRLVVSKLGLREEEYEHT--YQSKFGPEKWLEPATIDRVAELPKENAKKV 255 Query: 437 LAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAV 276 L +FV++ +ETL E+++E +E+ +E+G E + V + F L++ V Sbjct: 256 LICSPAFVADCLETLFELEIENKEVFVENGGETFDFVHPFNDSLDFTRVLSEVV 309
>HEMH_WOLSU (Q7M7P9) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 316 Score = 63.9 bits (154), Expect = 4e-10 Identities = 40/108 (37%), Positives = 63/108 (58%), Gaps = 1/108 (0%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRG-TLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVK 444 GDPY ++ I + + L+ RG T T AYQS+VGP++WL+P DEVL +L K + Sbjct: 198 GDPYEKEVHANIQALTKLLEERGITFKKITHAYQSKVGPMKWLEPSLDEVL-KLHAK--E 254 Query: 443 SLLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSF 300 +L P++F ++ ET E+ +EY+E A GI ++ L ++ F Sbjct: 255 KILLYPIAFTLDNSETDFELRIEYQEKATHLGITDYRVASCLNDSTRF 302
>HEMH_SYMTH (Q67T48) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 320 Score = 63.9 bits (154), Expect = 4e-10 Identities = 40/120 (33%), Positives = 60/120 (50%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS 441 GD Y Q E + + + + YQS+ G WL+P TDEVL EL + G + Sbjct: 204 GDDYAAQCESTTDAVRDRFPDLKIV----MGYQSKFGNDPWLEPATDEVLRELVRTGHRH 259 Query: 440 LLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVEALP 261 + + F ++ IETL E+++EY E +++G E + +PA FI L D V LP Sbjct: 260 VAVMAPGFAADCIETLHELEVEYAEEFVKAGGERYDYLPAANDHPLFIDCLEDLVRRHLP 319
>HEMH_NITEU (Q82UK8) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 364 Score = 63.9 bits (154), Expect = 4e-10 Identities = 37/101 (36%), Positives = 58/101 (57%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS 441 GDPY + + L+ E L+ + + + +QSR G QWL PYT E+L ELG++ Sbjct: 221 GDPYHCECQKTGRLLAEALELAD--DRYQICFQSRFGFAQWLGPYTAEILAELGKQKTGR 278 Query: 440 LLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPAL 318 + V FVS+ +ETLEEI +E + + E+G + +P+L Sbjct: 279 VDVVCPGFVSDCLETLEEIALEGKAIFTEAGGGEFHYIPSL 319
>HEMH_RHILO (Q98H61) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 353 Score = 63.9 bits (154), Expect = 4e-10 Identities = 38/103 (36%), Positives = 58/103 (56%), Gaps = 2/103 (1%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTL--AYQSRVGPVQWLKPYTDEVLVELGQKGV 447 GDPY+ + L+ E+L ++ L +QSR G +WL+PYTD+ + +LG+ GV Sbjct: 233 GDPYQAHCLETTRLLREKLG----WDEKKLITTFQSRFGAQEWLQPYTDKTVEKLGKDGV 288 Query: 446 KSLLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPAL 318 KS+ V F + IETL+EI E E +G +N+ +P L Sbjct: 289 KSIAIVNPGFSVDCIETLDEIGREAAETFHHAGGKNFAHIPCL 331
>HEMH_PHOLL (Q7N0P6) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 325 Score = 63.9 bits (154), Expect = 4e-10 Identities = 39/115 (33%), Positives = 60/115 (52%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS 441 GD Y +Q + L+ + + +AYQSR G QWL PY D+ + L +G+K Sbjct: 204 GDIYAEQCKLTTRLLKQAINY--PTEQVMMAYQSRFGREQWLTPYVDQTMKTLPNQGIKH 261 Query: 440 LLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAV 276 + + F S+ +ETLEEI +E+ L +G E + +PAL +S I L + V Sbjct: 262 IQVLCPGFSSDCLETLEEIKQLNKEMFLNAGGEKFEYIPALNDNASHILLLEELV 316
>HEMH_SALTI (Q8Z8T2) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 320 Score = 62.8 bits (151), Expect = 8e-10 Identities = 32/79 (40%), Positives = 46/79 (58%) Frame = -1 Query: 533 LAYQSRVGPVQWLKPYTDEVLVELGQKGVKSLLAVPVSFVSEHIETLEEIDMEYRELALE 354 + +QSR G WL PYTDE L LG+KG + + F ++ +ETLEEI + RE+ LE Sbjct: 231 MTFQSRFGREPWLTPYTDETLKMLGEKGTGHIQVMCPGFAADCLETLEEIAEQNREIFLE 290 Query: 353 SGIENWGRVPALGCTSSFI 297 +G + + + AL T I Sbjct: 291 AGGKKYAYIQALNATPEHI 309
>HEMH_CHLPN (Q9Z7V1) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 327 Score = 62.8 bits (151), Expect = 8e-10 Identities = 37/117 (31%), Positives = 61/117 (52%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS 441 GDPY Q + + I K +++ L +QS+ GP +WL P T ++ + + Sbjct: 197 GDPYSKQCYESFSAITTNFKQ----SENFLCFQSKFGPGKWLSPSTAQLCQNI-DTDKPN 251 Query: 440 LLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVE 270 ++ VP F+S+H+ETL EI+ +Y L G R+PA+ + ++S L D V E Sbjct: 252 VIVVPFGFISDHLETLYEIERDYLPLLRSRGYRAL-RIPAIYSSPLWVSTLVDIVKE 307
>HEMH_YERPS (Q05338) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 320 Score = 62.4 bits (150), Expect = 1e-09 Identities = 34/86 (39%), Positives = 47/86 (54%) Frame = -1 Query: 533 LAYQSRVGPVQWLKPYTDEVLVELGQKGVKSLLAVPVSFVSEHIETLEEIDMEYRELALE 354 + YQSR G WL PYTDE L L +GVK + + F ++ +ETLEEI + RE L Sbjct: 231 MTYQSRFGREPWLTPYTDETLKSLPSQGVKHIQLICPGFSADCLETLEEIKEQNREFFLH 290 Query: 353 SGIENWGRVPALGCTSSFISDLADAV 276 +G E + +PAL I+ L + Sbjct: 291 AGGEKFEYIPALNDDEGHIALLEQLI 316
>HEMH_YERPE (Q8ZC98) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 320 Score = 62.4 bits (150), Expect = 1e-09 Identities = 34/86 (39%), Positives = 47/86 (54%) Frame = -1 Query: 533 LAYQSRVGPVQWLKPYTDEVLVELGQKGVKSLLAVPVSFVSEHIETLEEIDMEYRELALE 354 + YQSR G WL PYTDE L L +GVK + + F ++ +ETLEEI + RE L Sbjct: 231 MTYQSRFGREPWLTPYTDETLKSLPSQGVKHIQLICPGFSADCLETLEEIKEQNREFFLH 290 Query: 353 SGIENWGRVPALGCTSSFISDLADAV 276 +G E + +PAL I+ L + Sbjct: 291 AGGEKFEYIPALNDDEGHIALLEQLI 316
>HEMH2_SHEON (Q8EBZ7) Ferrochelatase 2 (EC 4.99.1.1) (Protoheme ferro-lyase 2)| (Heme synthetase 2) Length = 327 Score = 62.4 bits (150), Expect = 1e-09 Identities = 37/115 (32%), Positives = 61/115 (53%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS 441 GDPY L+ E+L + ++ + +QSR G +WL+PYTD + L +GV+ Sbjct: 211 GDPYYCFCMKTTRLVAEQLGL--SKDEFAITFQSRFGKAKWLQPYTDATMAALPSQGVRD 268 Query: 440 LLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAV 276 + V +F ++ +ETLEEI E + +G E + +PAL I+ +A+ V Sbjct: 269 VAIVCPAFSADCLETLEEIVGENGHIFTHAGGEKFRYIPALNDNDDHIAMMANLV 323
>HEMH_BDEBA (Q6MHT3) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 335 Score = 61.6 bits (148), Expect = 2e-09 Identities = 40/113 (35%), Positives = 59/113 (52%), Gaps = 1/113 (0%) Frame = -1 Query: 611 YRDQMEDCIALIMEELKSRGTLNDH-TLAYQSRVGPVQWLKPYTDEVLVELGQKGVKSLL 435 YR Q C A +S H ++A+QSR+G +WLKP TD L L + G K++ Sbjct: 223 YRAQ---CFATATAIAESLNLAPSHWSVAFQSRLGRAEWLKPATDHSLEVLAKTGKKNIA 279 Query: 434 AVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAV 276 + SFV++ IETLEEI + +E E G + + VP + ++ AD V Sbjct: 280 VICPSFVADCIETLEEIGIGGQETFHEHGGDQYYLVPCVNDNPKWVQGFADLV 332
>HEMH_VIBCH (Q9KTB6) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 320 Score = 61.2 bits (147), Expect = 2e-09 Identities = 33/86 (38%), Positives = 52/86 (60%) Frame = -1 Query: 533 LAYQSRVGPVQWLKPYTDEVLVELGQKGVKSLLAVPVSFVSEHIETLEEIDMEYRELALE 354 + YQS+ G +WL+PYTD+ + L ++G+K L + +F + +ETLEEI + +E+ L Sbjct: 231 MTYQSQFGKEEWLQPYTDKTMEALPRQGIKKLDVICPAFSVDCLETLEEIAEQNQEIFLH 290 Query: 353 SGIENWGRVPALGCTSSFISDLADAV 276 SG E + VP L + S I +A V Sbjct: 291 SGGEAFHYVPCLNDSQSHIELMAALV 316
>HEMH_PSEFL (P57778) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 340 Score = 60.8 bits (146), Expect = 3e-09 Identities = 39/99 (39%), Positives = 57/99 (57%), Gaps = 1/99 (1%) Frame = -1 Query: 611 YRDQMEDCIALIMEELKSRGTLNDH-TLAYQSRVGPVQWLKPYTDEVLVELGQKGVKSLL 435 YR Q C ++ + G +D ++A+QSR+G +W++PYT+ L L Q+GVK LL Sbjct: 224 YRGQ---CFSVARDFAARMGLPDDKWSVAFQSRLGRAKWIEPYTEARLEALAQQGVKKLL 280 Query: 434 AVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPAL 318 + +FV++ IETLEEI E E+G E VP L Sbjct: 281 VMCPAFVADCIETLEEIGDRGLEQFREAGGEELVLVPCL 319
>HEMH_CORGL (Q8NQA1) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 370 Score = 60.5 bits (145), Expect = 4e-09 Identities = 40/120 (33%), Positives = 65/120 (54%), Gaps = 2/120 (1%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGP--VQWLKPYTDEVLVELGQKGV 447 G Y Q+++ ALI E + ++D + +QSR G WL+P + VEL +KG Sbjct: 205 GSLYSTQVKEASALIAEAVG----VSDFDVVWQSRSGSPHTPWLEPDIVDHAVELNEKGQ 260 Query: 446 KSLLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVEA 267 K+L+ PV F+S+H+E + ++D E E A + + RV +G T F + + D + EA Sbjct: 261 KALVVCPVGFISDHMEVIWDLDSELMEEAEKRNMV-VERVATVGPTDEFAALVVDLIEEA 319
>HEMH_NEIMB (Q9K097) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 336 Score = 59.7 bits (143), Expect = 7e-09 Identities = 36/121 (29%), Positives = 64/121 (52%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS 441 GDPY D+ L+ E L+ T + + +++QS+ G +W+ P T ++ +L ++GV Sbjct: 216 GDPYPDECRHTAKLLAEALEL--TEDQYVVSFQSQFGRAKWVTPSTQDLFGKLPKQGVTE 273 Query: 440 LLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVEALP 261 L F+++ +ET+EEI + RE E+G +++ +P L +I L E L Sbjct: 274 LDVFCPGFLADCLETMEEIALMGREQFYEAGGKSYRYIPCLNDNPDWIDALVALAEENLG 333 Query: 260 S 258 S Sbjct: 334 S 334
>HEMH_METCA (Q607T4) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 325 Score = 59.3 bits (142), Expect = 9e-09 Identities = 36/104 (34%), Positives = 55/104 (52%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS 441 GDPY Q + I L+ ++ L YQSR G +WL+PY + L EL +G++ Sbjct: 205 GDPYASQCQATAQGIARLLELSD--DEWLLTYQSRFGRAEWLRPYCIDTLRELPSQGIRH 262 Query: 440 LLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCT 309 + V F + +ETLEEI + R L +G +N+ +PAL + Sbjct: 263 VDVVCPGFAVDCLETLEEIAIANRNEFLGAGGKNYRYIPALNAS 306
>HEMH_PSESM (Q888A2) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 340 Score = 59.3 bits (142), Expect = 9e-09 Identities = 33/83 (39%), Positives = 51/83 (61%) Frame = -1 Query: 536 TLAYQSRVGPVQWLKPYTDEVLVELGQKGVKSLLAVPVSFVSEHIETLEEIDMEYRELAL 357 ++++QSR+G +W++PYT+ L EL +GVK LL + +FV++ IETLEEI E Sbjct: 247 SVSFQSRLGRAKWIEPYTEARLDELAAQGVKKLLVMCPAFVADCIETLEEIGDRGAEQFK 306 Query: 356 ESGIENWGRVPALGCTSSFISDL 288 E+G E VP L ++ +L Sbjct: 307 EAGGEELILVPCLNDDPNWAKEL 329
>HEMH_NEIMA (Q9JVA5) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 336 Score = 58.9 bits (141), Expect = 1e-08 Identities = 35/119 (29%), Positives = 63/119 (52%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS 441 GDPY D+ L+ E L+ T + + +++QS+ G +W+ P T ++ +L ++GV Sbjct: 216 GDPYPDECRHTAKLLAEALEL--TEDQYVVSFQSQFGRAKWVTPSTQDLFGKLPKQGVTE 273 Query: 440 LLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVEAL 264 L F+++ +ET+EEI + RE E+G +++ +P L +I L E L Sbjct: 274 LDVFCPGFLADCLETMEEIALMGREQFYEAGGKSYRYIPCLNDNPDWIDALVALAEENL 332
>HEMH_ERWCT (Q6D7Z4) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 320 Score = 58.5 bits (140), Expect = 2e-08 Identities = 29/72 (40%), Positives = 44/72 (61%) Frame = -1 Query: 533 LAYQSRVGPVQWLKPYTDEVLVELGQKGVKSLLAVPVSFVSEHIETLEEIDMEYRELALE 354 + +QSR G WL PYTDE + L +G+K + + F ++ +ETLEEI + RE+ L Sbjct: 231 MTFQSRFGREPWLTPYTDETMQGLPAQGIKHIQIMCPGFAADCLETLEEIQEQNREIFLH 290 Query: 353 SGIENWGRVPAL 318 +G E + +PAL Sbjct: 291 AGGEAFHYIPAL 302
>HEMH_WIGBR (Q8D226) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 321 Score = 58.5 bits (140), Expect = 2e-08 Identities = 34/116 (29%), Positives = 66/116 (56%), Gaps = 1/116 (0%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELK-SRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVK 444 GD Y + L++ +L SR + +++QS+ G + W+ P T EV+ L +KG+K Sbjct: 204 GDDYLKRCNVTKKLVLSKLNFSRKKV---IMSFQSKFGNIPWITPITSEVISFLPKKGIK 260 Query: 443 SLLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAV 276 ++ + F S+ +ETLEEI ++ +++ ++G + + +PAL + I LA+ + Sbjct: 261 NIQVICPGFSSDCLETLEEIKIQNKKIFKDNGGKKFHYIPALNYSKIHIECLANII 316
>HEMH_TROWT (Q83FJ2) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 391 Score = 58.5 bits (140), Expect = 2e-08 Identities = 41/132 (31%), Positives = 68/132 (51%), Gaps = 3/132 (2%) Frame = -1 Query: 611 YRDQMEDCIALIMEELK-SRGTLNDHTLAYQSRVGP--VQWLKPYTDEVLVELGQKGVKS 441 Y Q + + +IM L+ + L ++ L YQSR G WL+P ++ + L +G ++ Sbjct: 234 YVSQHKAVVEVIMSRLRVTDPDLQNYQLVYQSRSGDPSTPWLEPDINDAIRVL--RGCEA 291 Query: 440 LLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVEALP 261 +L VP+ F+S+H+E L ++D E + A E G+ R P G +IS + D +VE L Sbjct: 292 VLIVPLGFISDHMEVLWDLDNESMQTARECGLFAI-RTPTPGTHPLYISGMVDLIVERLE 350 Query: 260 SASAMATRKVKD 225 A + D Sbjct: 351 GVPRSARPAMTD 362
>HEMH_TROW8 (Q83H94) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 391 Score = 58.5 bits (140), Expect = 2e-08 Identities = 41/132 (31%), Positives = 68/132 (51%), Gaps = 3/132 (2%) Frame = -1 Query: 611 YRDQMEDCIALIMEELK-SRGTLNDHTLAYQSRVGP--VQWLKPYTDEVLVELGQKGVKS 441 Y Q + + +IM L+ + L ++ L YQSR G WL+P ++ + L +G ++ Sbjct: 234 YVSQHKAVVEVIMSRLRVTDPDLQNYQLVYQSRSGDPSTPWLEPDINDAIRVL--RGCEA 291 Query: 440 LLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVEALP 261 +L VP+ F+S+H+E L ++D E + A E G+ R P G +IS + D +VE L Sbjct: 292 VLIVPLGFISDHMEVLWDLDNESMQTARECGLFAI-RTPTPGTHPLYISGMVDLIVERLE 350 Query: 260 SASAMATRKVKD 225 A + D Sbjct: 351 GVPRSARPAMTD 362
>HEMH_XANAC (Q8PEX0) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 318 Score = 57.4 bits (137), Expect = 3e-08 Identities = 36/112 (32%), Positives = 55/112 (49%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS 441 GDPY Q E I+ L ++ + YQSR G +WL+PY + L +L + GV+S Sbjct: 204 GDPYPQQCERSAQAIVAALGLGA--DEWQMGYQSRFGAERWLQPYAEPTLWKLAEGGVRS 261 Query: 440 LLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLA 285 V F ++ +ETLEE+ + + E E G +P L + + LA Sbjct: 262 FDLVCPGFATDCLETLEEVALGFSETLAERG-ATLSYIPCLNASDAHAHALA 312
>HEMH_PHOPR (Q6LTE0) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 322 Score = 57.0 bits (136), Expect = 4e-08 Identities = 34/117 (29%), Positives = 59/117 (50%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS 441 GDPY + E L +++YQS G +WL+PYT+ + L QKG+K Sbjct: 203 GDPYPQHCHATTEKLAERLAM--PREKMSMSYQSIFGREEWLQPYTEVTIEALAQKGIKR 260 Query: 440 LLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVE 270 L + +F + +ETLEEI + +E +++G + + +P L + I + + V + Sbjct: 261 LDVMCPAFSVDCLETLEEIAEQCKETFIKAGGDVFNLIPCLNDNEAHIRMMKNLVTQ 317
>HEMH_RALSO (Q8XW32) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 371 Score = 56.6 bits (135), Expect = 6e-08 Identities = 37/113 (32%), Positives = 58/113 (51%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS 441 GDPY L+ E L + + + +QSR G +WL+PYT L ELG+ G Sbjct: 228 GDPYHCACLKTGRLLGEALGLQP--GQYLVTFQSRFGRAEWLQPYTAPTLEELGRVGTGR 285 Query: 440 LLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLAD 282 + F ++ +ETLEEI ME + +G +++ +P L + +I+ LAD Sbjct: 286 VDVFCPGFPADCLETLEEIAMEGQSTFRVAGGKDFHYIPCLNDSEPWIAGLAD 338
>HEMH_NOCFA (Q5YU18) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 352 Score = 56.6 bits (135), Expect = 6e-08 Identities = 28/68 (41%), Positives = 44/68 (64%), Gaps = 2/68 (2%) Frame = -1 Query: 542 DHTLAYQSRVGPVQ--WLKPYTDEVLVELGQKGVKSLLAVPVSFVSEHIETLEEIDMEYR 369 DH L +QSR GP Q WL+P + L +L +GV +++ PV FVS+H+E + ++D E + Sbjct: 220 DHDLVWQSRSGPPQVPWLEPDIVDHLEDLAGRGVDAVVVCPVGFVSDHLEVIWDLDNEAK 279 Query: 368 ELALESGI 345 + A E G+ Sbjct: 280 DKAAELGM 287
>HEMH_RHOBA (Q7UFZ7) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 351 Score = 56.2 bits (134), Expect = 7e-08 Identities = 35/96 (36%), Positives = 52/96 (54%), Gaps = 3/96 (3%) Frame = -1 Query: 542 DHTLAYQSRVGPVQ--WLKPYTDEVLVELGQ-KGVKSLLAVPVSFVSEHIETLEEIDMEY 372 D L YQSR GP WL+P + + E+ K ++SL+ +P+ FVS+H+E L ++D E Sbjct: 215 DWDLVYQSRSGPPSQPWLEPDVLDAIAEMDDAKKLESLVILPIGFVSDHMEVLFDLDEEA 274 Query: 371 RELALESGIENWGRVPALGCTSSFISDLADAVVEAL 264 +L E GI+ R A G F+ + V E L Sbjct: 275 AQLCRERGIK-MARASAAGTHPDFVEMICGLVQERL 309
>HEMH_STRR6 (Q8DQ04) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 364 Score = 56.2 bits (134), Expect = 7e-08 Identities = 40/115 (34%), Positives = 59/115 (51%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS 441 GDPY DQ+ + L+ E+L +T +S +G + W+KP E L E + Sbjct: 179 GDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIG-IPWIKPDVLEYLREQTEHP-DH 236 Query: 440 LLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAV 276 + VP+SF+SEHIE L + D+E +L E G+ N+ R P S I L + V Sbjct: 237 YIFVPISFISEHIEVLFDNDVECYDLCQEFGV-NYHRPPMPNTDSRLIDALVNTV 290
>HEMH_STRPN (Q97R30) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 364 Score = 56.2 bits (134), Expect = 7e-08 Identities = 40/115 (34%), Positives = 59/115 (51%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS 441 GDPY DQ+ + L+ E+L +T +S +G + W+KP E L E + Sbjct: 179 GDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIG-IPWIKPDVLEYLREQTEHP-DH 236 Query: 440 LLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAV 276 + VP+SF+SEHIE L + D+E +L E G+ N+ R P S I L + V Sbjct: 237 YIFVPISFISEHIEVLFDNDVECYDLCQEFGV-NYHRPPMPNTDSRLIDALVNTV 290
>HEMH_XYLFT (Q87B82) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 320 Score = 55.1 bits (131), Expect = 2e-07 Identities = 36/120 (30%), Positives = 55/120 (45%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS 441 GDPY + + +LI L + + L YQSR G +WL+PY + L L + G++ Sbjct: 204 GDPYPQRCQVSASLIAAALNLNES--EWVLGYQSRFGAERWLQPYAEPTLWALAESGIRR 261 Query: 440 LLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVEALP 261 V F + +ETLEE+ + + E G +P L + + LA ALP Sbjct: 262 FDLVCPGFSVDCLETLEEVALGFSETLAARG-ATMRYIPCLNDDPAHVQALAGLAQRALP 320
>HEMH_COREF (Q8FTB1) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 377 Score = 55.1 bits (131), Expect = 2e-07 Identities = 39/120 (32%), Positives = 63/120 (52%), Gaps = 3/120 (2%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGP--VQWLKPYTDEVLVELGQK-G 450 G Y Q+E+ ALI E ++D + +QSR G V WL+P + VEL + G Sbjct: 210 GSIYSRQVEESSALIARE----AGIDDFDVVWQSRSGSPHVPWLEPDIVDHAVELNENNG 265 Query: 449 VKSLLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVE 270 K+L+ PV F+S+H+E + ++D E + A G+ RV +G + F + + D + E Sbjct: 266 QKALVVCPVGFISDHMEVIWDLDSELMDEATRRGMV-IERVATVGPSDEFATMVVDLIDE 324
>HEMH_XANCP (Q8P3H6) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 318 Score = 54.7 bits (130), Expect = 2e-07 Identities = 43/129 (33%), Positives = 61/129 (47%), Gaps = 1/129 (0%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDH-TLAYQSRVGPVQWLKPYTDEVLVELGQKGVK 444 GDPY Q E I+ L G D + YQSR G +WL+PY + L L + GV+ Sbjct: 204 GDPYPQQCERSAQAIVTAL---GLGPDAWQMGYQSRFGAERWLQPYAEPTLWALAEGGVR 260 Query: 443 SLLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVEAL 264 S V F ++ +ETLEE+ + + E E G T S+I L D+ A Sbjct: 261 SFDLVCPGFATDCLETLEEVALGFAETLAER-----------GATLSYIPCLNDSTTHA- 308 Query: 263 PSASAMATR 237 + +A+A R Sbjct: 309 QALAAVARR 317
>HEMH_OCEIH (Q8ERX9) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 312 Score = 54.3 bits (129), Expect = 3e-07 Identities = 38/123 (30%), Positives = 64/123 (52%), Gaps = 2/123 (1%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVG-PVQWLKPYTDEVLVELGQ-KGV 447 GDPY+ Q+E+ LI+EE + ++ + +QS P WL P ++ EL + +G Sbjct: 192 GDPYKHQLEETAKLIVEE----ADVKNYAVGWQSEGNTPDPWLGPDVQDLTRELYESEGY 247 Query: 446 KSLLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVEA 267 K+ + PV FV++H+E L + D E + + E G ++ R FI LA+ V++ Sbjct: 248 KAFIYTPVGFVADHLEVLYDNDYECKVVCDEIG-ASYYRPDMPNVHPEFIETLANVVMKK 306 Query: 266 LPS 258 S Sbjct: 307 AKS 309
>HEMH_HELHP (Q7VHH1) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 311 Score = 54.3 bits (129), Expect = 3e-07 Identities = 34/120 (28%), Positives = 59/120 (49%), Gaps = 1/120 (0%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTL-NDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVK 444 GDPY+ Q E+ +I + L+S G + LAYQS+VG ++W+ P T E + + + Sbjct: 189 GDPYQKQCEENKEVIQKALESEGIVFKKIALAYQSKVGRMKWIGPSTKETITKYKK---H 245 Query: 443 SLLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVEAL 264 ++ P+SF ++ ET E+ + Y LA E + + F + + + E L Sbjct: 246 KMIIFPLSFTLDNSETEYELKILYASLAKELNVPQYRVCSCFNDNERFAKSIMNILEEHL 305
>HEMH_STRAW (Q82KJ6) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 375 Score = 54.3 bits (129), Expect = 3e-07 Identities = 40/121 (33%), Positives = 62/121 (51%), Gaps = 4/121 (3%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHT--LAYQSRVGP--VQWLKPYTDEVLVELGQK 453 G Y Q D LI + ++ + DH L YQSR G + WL+P + L EL Sbjct: 210 GGAYVKQHLDVARLIADAVREETGI-DHPWQLVYQSRSGAPHIPWLEPDICDHLQELHGA 268 Query: 452 GVKSLLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVV 273 GV +++ P+ FVS+H+E L ++D E + A E G+ R +G + F + + + VV Sbjct: 269 GVPAVVMAPIGFVSDHMEVLYDLDTEAKAKAEELGLP-VRRSATVGADARFAAAVRELVV 327 Query: 272 E 270 E Sbjct: 328 E 328
>HEMH_MYCLE (Q9CBM2) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 336 Score = 53.9 bits (128), Expect = 4e-07 Identities = 26/68 (38%), Positives = 41/68 (60%), Gaps = 2/68 (2%) Frame = -1 Query: 542 DHTLAYQSRVGP--VQWLKPYTDEVLVELGQKGVKSLLAVPVSFVSEHIETLEEIDMEYR 369 D+ L +QSR GP V WL P + L+ L G K+++ P+ FV++HIE + ++D E R Sbjct: 210 DYDLTWQSRSGPPYVPWLAPDVGDQLMTLASAGTKAVIVCPIGFVADHIEVVWDLDHELR 269 Query: 368 ELALESGI 345 A +G+ Sbjct: 270 SQADAAGV 277
>HEMH_MYCPA (Q740Y1) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 336 Score = 53.5 bits (127), Expect = 5e-07 Identities = 25/68 (36%), Positives = 43/68 (63%), Gaps = 2/68 (2%) Frame = -1 Query: 542 DHTLAYQSRVGP--VQWLKPYTDEVLVELGQKGVKSLLAVPVSFVSEHIETLEEIDMEYR 369 +H L +QSR GP V+WL+P + L L + G ++++ P+ FV++HIE + ++D E R Sbjct: 206 EHDLVWQSRSGPPQVRWLEPDVADHLRALAESGTRAVIVCPIGFVADHIEVVWDLDEELR 265 Query: 368 ELALESGI 345 A +G+ Sbjct: 266 AQAESAGM 273
>HEMH_MYCAV (O07401) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 335 Score = 53.5 bits (127), Expect = 5e-07 Identities = 25/68 (36%), Positives = 43/68 (63%), Gaps = 2/68 (2%) Frame = -1 Query: 542 DHTLAYQSRVGP--VQWLKPYTDEVLVELGQKGVKSLLAVPVSFVSEHIETLEEIDMEYR 369 +H L +QSR GP V+WL+P + L L + G ++++ P+ FV++HIE + ++D E R Sbjct: 205 EHDLVWQSRSGPPQVRWLEPDVADHLRALAESGTRAVIVCPIGFVADHIEVVWDLDEELR 264 Query: 368 ELALESGI 345 A +G+ Sbjct: 265 AQAESAGM 272
>HEMH_BACSK (Q5WHT1) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 312 Score = 53.1 bits (126), Expect = 6e-07 Identities = 36/120 (30%), Positives = 61/120 (50%), Gaps = 2/120 (1%) Frame = -1 Query: 617 DPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVG-PVQWLKPYTDEVLVEL-GQKGVK 444 DPY +Q+ + L+ + + ++ + +QS P WL P ++ EL +KG K Sbjct: 192 DPYPEQLRETADLLAD----MANVPNYEIGWQSEGNTPEPWLGPDVQDLTRELYAKKGYK 247 Query: 443 SLLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVEAL 264 + + PV FV+EH+E L + D E + + E G+ + R P + F+ LAD V + L Sbjct: 248 TFMYCPVGFVAEHLEVLYDNDYECKLVTDELGV-RYLRPPMPNADTRFLKALADVVTKRL 306
>HEMH_PARUW (Q6MAW8) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 347 Score = 53.1 bits (126), Expect = 6e-07 Identities = 32/109 (29%), Positives = 53/109 (48%) Frame = -1 Query: 563 KSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKSLLAVPVSFVSEHIETLEEI 384 K R L +T+ +QSR+G W++PYT ++L + K K +L +FV + +ET E+ Sbjct: 239 KLRIKLEQYTVCFQSRLGKETWIQPYTSDLLKDCLAKNRKKILVFCPAFVCDCLETTCEV 298 Query: 383 DMEYRELALESGIENWGRVPALGCTSSFISDLADAVVEALPSASAMATR 237 +EY E G + V L +I + + E LP + +R Sbjct: 299 SIEYAEEFKHLGGDTLHLVEGLNSHPVWIEAIKTIIQEHLPHPHSQFSR 347
>HEMH_STRCO (O50533) Probable ferrochelatase (EC 4.99.1.1) (Protoheme| ferro-lyase) (Heme synthetase) Length = 375 Score = 52.8 bits (125), Expect = 8e-07 Identities = 39/120 (32%), Positives = 59/120 (49%), Gaps = 3/120 (2%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSR-GTLNDHTLAYQSRVGP--VQWLKPYTDEVLVELGQKG 450 G Y Q D LI + ++ R G + L YQSR G + WL+P + L E G Sbjct: 210 GGAYVRQHLDVARLIADAVRERTGVDHPWQLVYQSRSGAPHIPWLEPDICDHLEERQAAG 269 Query: 449 VKSLLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVE 270 V +++ P+ FVS+H+E L ++D E A E G+ R +G F + + D V+E Sbjct: 270 VPAVVMAPIGFVSDHMEVLYDLDTEATAKAEELGLP-VRRSATVGADPRFAAAVRDLVLE 328
>HEMH_ZYMMO (P57779) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 334 Score = 52.4 bits (124), Expect = 1e-06 Identities = 30/82 (36%), Positives = 45/82 (54%) Frame = -1 Query: 530 AYQSRVGPVQWLKPYTDEVLVELGQKGVKSLLAVPVSFVSEHIETLEEIDMEYRELALES 351 ++QSR G +W P TD L EL K +++L F ++ +ETLEEI ++ + LE+ Sbjct: 238 SFQSRFGSQKWFTPATDMTLKELPSKNIRNLAVAMPGFSADCLETLEEIALQGKSTFLEA 297 Query: 350 GIENWGRVPALGCTSSFISDLA 285 G EN+ AL C + LA Sbjct: 298 GGENFA---ALRCLNDSEESLA 316
>HEMH_MYCTU (P0A576) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 344 Score = 52.4 bits (124), Expect = 1e-06 Identities = 27/68 (39%), Positives = 41/68 (60%), Gaps = 2/68 (2%) Frame = -1 Query: 542 DHTLAYQSRVGPVQ--WLKPYTDEVLVELGQKGVKSLLAVPVSFVSEHIETLEEIDMEYR 369 D LA+QSR GP Q WL+P + L L G+ +++ P+ FV++HIE + ++D E R Sbjct: 206 DFDLAWQSRSGPPQVPWLEPDVTDQLTGLAGAGINAVIVCPIGFVADHIEVVWDLDHELR 265 Query: 368 ELALESGI 345 A +GI Sbjct: 266 LQAEAAGI 273
>HEMH_MYCBO (P0A577) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 344 Score = 52.4 bits (124), Expect = 1e-06 Identities = 27/68 (39%), Positives = 41/68 (60%), Gaps = 2/68 (2%) Frame = -1 Query: 542 DHTLAYQSRVGPVQ--WLKPYTDEVLVELGQKGVKSLLAVPVSFVSEHIETLEEIDMEYR 369 D LA+QSR GP Q WL+P + L L G+ +++ P+ FV++HIE + ++D E R Sbjct: 206 DFDLAWQSRSGPPQVPWLEPDVTDQLTGLAGAGINAVIVCPIGFVADHIEVVWDLDHELR 265 Query: 368 ELALESGI 345 A +GI Sbjct: 266 LQAEAAGI 273
>HEMH_XYLFA (Q9PFU1) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 320 Score = 52.0 bits (123), Expect = 1e-06 Identities = 35/119 (29%), Positives = 54/119 (45%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS 441 GDPY + + +LI L + + L YQSR G +WL+PY + L L + G++ Sbjct: 204 GDPYPQRCQVSASLIAAALDLNES--EWVLGYQSRFGAERWLQPYAEPTLWALAESGIRR 261 Query: 440 LLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVEAL 264 V F + +ETLEE+ + + E G +P L + + LA AL Sbjct: 262 FDLVCPGFSVDCLETLEEVALGFSETLAARG-ATMRYIPCLNDDPAHVQALAGLAQRAL 319
>HEMH_THET2 (Q72L32) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 317 Score = 52.0 bits (123), Expect = 1e-06 Identities = 39/121 (32%), Positives = 59/121 (48%), Gaps = 1/121 (0%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVG-PVQWLKPYTDEVLVELGQKGVK 444 GDPY Q+E LI ++L L +AYQS P WL P +E+L L ++G + Sbjct: 201 GDPYPRQVEKTAELIAKKL----ALPRFHVAYQSAGRTPEPWLGPDINELLRTLKEEGYE 256 Query: 443 SLLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVEAL 264 + V F ++H+E ++D+E + A E G+ R +L +I L D V A Sbjct: 257 EVAVQAVGFPADHLEVFYDLDLEAQATARELGLRLL-RARSLNADLDYIQVLKDLVEAAW 315 Query: 263 P 261 P Sbjct: 316 P 316
>HEMH_BACSU (P32396) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 310 Score = 51.2 bits (121), Expect = 2e-06 Identities = 37/121 (30%), Positives = 62/121 (51%), Gaps = 2/121 (1%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVG-PVQWLKPYTDEVLVEL-GQKGV 447 GDPY DQ+ + LI E ++++ + +QS P WL P ++ +L QKG Sbjct: 193 GDPYPDQLHESAKLIAEG----AGVSEYAVGWQSEGNTPDPWLGPDVQDLTRDLFEQKGY 248 Query: 446 KSLLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVEA 267 ++ + VPV FV++H+E L + D E + + + G ++ R FI LA V++ Sbjct: 249 QAFVYVPVGFVADHLEVLYDNDYECKVVTDDIG-ASYYRPEMPNAKPEFIDALATVVLKK 307 Query: 266 L 264 L Sbjct: 308 L 308
>HEMH_CORDI (Q6NH66) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 369 Score = 51.2 bits (121), Expect = 2e-06 Identities = 32/119 (26%), Positives = 59/119 (49%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKS 441 G Y Q+ + +L+ + L D S G + WL+P + +GV Sbjct: 213 GPLYSRQVYEAASLVAKHLGISQERYDVVWQSASGNGQIPWLEPDILDYAKCQHDEGVSE 272 Query: 440 LLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVEAL 264 L+ P+ F+S+H+E + ++D E ++LA + G+ + R +G T SF + + + V E+L Sbjct: 273 LVVAPIGFISDHMEVVWDLDHELQDLASDLGM-SISRAATVGHTDSFATMIVELVEESL 330
>HEMH_PORGI (Q7MXP4) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 345 Score = 49.7 bits (117), Expect = 7e-06 Identities = 36/115 (31%), Positives = 58/115 (50%), Gaps = 1/115 (0%) Frame = -1 Query: 611 YRDQMEDCIALIMEELKSRGTLNDHT-LAYQSRVGPVQWLKPYTDEVLVELGQKGVKSLL 435 YR Q ALI E L G + +QSRVG +WL+PY E L Q+ K +L Sbjct: 234 YRYQTYRTTALIREAL---GLAEEQVEQVFQSRVGHTEWLRPYLIERLSAWPQEETKRIL 290 Query: 434 AVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVE 270 SFV + +E+LEE+ + + ++G ++ +P L +++I L + + E Sbjct: 291 IACPSFVCDCLESLEEVADHGQSIFKKAGGADFTYIPCLNSGANWIDALRNILEE 345
>HEMH_BACHD (Q9KDK9) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 310 Score = 46.2 bits (108), Expect = 8e-05 Identities = 37/121 (30%), Positives = 59/121 (48%), Gaps = 2/121 (1%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVG-PVQWLKPYTDEVLVELGQK-GV 447 GDPY Q+++ LI K G N + + +QS P WL P ++ +L + G Sbjct: 191 GDPYPQQLKETADLIA---KGAGITN-YAVGWQSEGNTPEPWLGPDVQDLTRDLYETHGY 246 Query: 446 KSLLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVEA 267 S++ PV FV++H+E L + D E + + E GI+ + R FI LA + + Sbjct: 247 TSMIYCPVGFVADHLEVLYDNDYECKVVTDELGIDYY-RPEMPNAKPEFIDCLATVIQKK 305 Query: 266 L 264 L Sbjct: 306 L 306
>HEMH_GEOKA (Q5L283) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 316 Score = 46.2 bits (108), Expect = 8e-05 Identities = 34/119 (28%), Positives = 58/119 (48%), Gaps = 2/119 (1%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSR-VGPVQWLKPYTDEVLVEL-GQKGV 447 GDPY Q+ED I ++ + + + +QS P WL P ++ +L ++G Sbjct: 193 GDPYPTQLEDTAKRIADQ----AGVAHYAVGWQSAGQTPEPWLGPDVQDLTRQLYEERGY 248 Query: 446 KSLLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVE 270 S + PV FV++H+E L + D+E +++ E G + R FI LA V++ Sbjct: 249 TSFVYAPVGFVADHLEVLYDNDIECKQVTEEIGARYY-RPEMPNTNPLFIDALASVVLK 306
>HEMH_LISIN (Q929G2) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 309 Score = 45.8 bits (107), Expect = 1e-04 Identities = 36/120 (30%), Positives = 59/120 (49%), Gaps = 3/120 (2%) Frame = -1 Query: 617 DPYRDQMEDCIALIMEELKSRGTLNDHTLAYQS--RVGPVQWLKPYTDEVLVEL-GQKGV 447 DPY DQ+++ LI +++ + + L +QS + G WL P ++ EL G++ Sbjct: 193 DPYPDQLQETADLIFDKV----AVPHYALGWQSEGKTGE-PWLGPDVQDLTRELYGREKY 247 Query: 446 KSLLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVEA 267 K + PV FV+EH+E L + D E + + E G + R P F+ L V +A Sbjct: 248 KHFIYTPVGFVAEHLEVLYDNDYECKVVTDEVGAA-YHRPPMPNADPEFLEVLRTVVWDA 306
>HEMH_LISMF (Q71XF4) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 309 Score = 45.1 bits (105), Expect = 2e-04 Identities = 36/119 (30%), Positives = 57/119 (47%), Gaps = 3/119 (2%) Frame = -1 Query: 617 DPYRDQMEDCIALIMEELKSRGTLNDHTLAYQS--RVGPVQWLKPYTDEVLVEL-GQKGV 447 DPY DQ+++ I E++ + + L +QS + G WL P ++ EL G++ Sbjct: 193 DPYPDQLQETADFIFEKV----VVPHYALGWQSEGKTGE-PWLGPDVQDLTRELYGREKY 247 Query: 446 KSLLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVE 270 K + PV FV+EH+E L + D E + + E G + R P F+ L V E Sbjct: 248 KHFIYTPVGFVAEHLEVLYDNDYECKVVTDEVG-ATYHRPPMPNSDPEFLEVLRTVVWE 305
>HEMH_THEVO (Q978U9) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 304 Score = 40.0 bits (92), Expect = 0.006 Identities = 22/65 (33%), Positives = 39/65 (60%) Frame = -1 Query: 446 KSLLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVEA 267 K ++AVP+SF+ +H+E L ++D E+R+ E G ++ RVP ++ FI+ L V + Sbjct: 226 KKIIAVPISFLYDHLEILYDLDYEFRKKIEEDGY-SYERVPMPNDSAIFITLLERIVSSS 284 Query: 266 LPSAS 252 + S Sbjct: 285 ITHLS 289
>HEMH_THEAC (Q9HLB8) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme| synthetase) Length = 308 Score = 35.4 bits (80), Expect = 0.14 Identities = 25/106 (23%), Positives = 53/106 (50%), Gaps = 7/106 (6%) Frame = -1 Query: 512 GPVQWLKPYTDEVLVELGQKGVKSLLAVPVSFVSEHIETLEEIDMEYRELALESGIENWG 333 G + WL P +VL + + +P+SF+ +H+E L ++D E+R+ A+E+ ++ Sbjct: 205 GHLGWLGPSIYDVLNRID---ASKITVIPISFLYDHLEILYDLDYEFRK-AVEAKGMHYR 260 Query: 332 RVPALGCTSSFISDLADAVVEALP-------SASAMATRKVKDTDS 216 RV ++ ++ + A A+ + S + ++ DTD+ Sbjct: 261 RVRMPNDSAMMVNMIERAARSAITHLSGEKINGSIIGQPRIADTDN 306
>EFG_HELHP (Q7VJ85) Elongation factor G (EF-G)| Length = 692 Score = 33.9 bits (76), Expect = 0.40 Identities = 30/108 (27%), Positives = 52/108 (48%), Gaps = 9/108 (8%) Frame = -1 Query: 392 EEIDMEYRELALESGIENWGRVPALGCTSSF----ISDLADAVVEALPSASAMATRKVKD 225 EE+ +E + ++ G N +P L C SSF + L DAVV+ LP+ + +A K D Sbjct: 234 EELSIEDIKKGIKIGCLNMSLIPML-CGSSFKNKGVQTLLDAVVDYLPAPTEVAEIKGID 292 Query: 224 TDSDMDMMHYLTKMFLGSVLAFFLLLSP-----RLVSAFRNTLQ*AAY 96 ++ ++ + + LAF ++ P V A+R L+ +Y Sbjct: 293 PKNESELSVESSDDGAFAGLAFKIMTDPFVGQLTFVRAYRGKLESGSY 340
>Y1816_METTH (O27844) UPF0286 protein MTH1816| Length = 253 Score = 32.3 bits (72), Expect = 1.2 Identities = 25/74 (33%), Positives = 40/74 (54%) Frame = -1 Query: 584 ALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKSLLAVPVSFVSEH 405 +L++ ELKSR ++ V V+ LK Y DE + + GV+ +L P S + Sbjct: 175 SLMIIELKSR----------KAGVSAVKQLKRYVDEFRED--RVGVRGVLVAP-SITHDA 221 Query: 404 IETLEEIDMEYREL 363 +E LEE +E+RE+ Sbjct: 222 MEMLEEEGLEFREI 235
>MTMRD_HUMAN (Q86WG5) Myotubularin-related protein 13 (SET-binding factor 2)| Length = 1849 Score = 31.6 bits (70), Expect = 2.0 Identities = 19/50 (38%), Positives = 28/50 (56%), Gaps = 2/50 (4%) Frame = -1 Query: 506 VQWLKPYTDEVLVELG--QKGVKSLLAVPVSFVSEHIETLEEIDMEYREL 363 V+++ + D+V E G Q +KSL + V+ HIETLE + E R L Sbjct: 816 VRFITRFIDKVCTESGVTQDHIKSLHCMIPGIVAMHIETLEAVHRESRRL 865
>CLPX_FRATT (Q5NH46) ATP-dependent Clp protease ATP-binding subunit clpX| Length = 417 Score = 31.6 bits (70), Expect = 2.0 Identities = 15/57 (26%), Positives = 34/57 (59%) Frame = -1 Query: 593 DCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKSLLAVPV 423 +C++ E+++S G+ + ++++ PV+ +K Y D+ ++ GQ K +L+V V Sbjct: 31 ECVSKCAEKIRSTGSTSAEDISFEKLPKPVE-IKKYLDDYII--GQDNAKKVLSVAV 84
>MTMRD_XENLA (Q6NTN5) Myotubularin-related protein 13 (SET-binding factor 2)| Length = 1873 Score = 31.6 bits (70), Expect = 2.0 Identities = 19/50 (38%), Positives = 28/50 (56%), Gaps = 2/50 (4%) Frame = -1 Query: 506 VQWLKPYTDEVLVELG--QKGVKSLLAVPVSFVSEHIETLEEIDMEYREL 363 V+++ + D+V E G Q +KSL + V+ HIETLE + E R L Sbjct: 814 VRFITRFIDKVCTESGVTQDHIKSLHCMIPGIVAMHIETLEAVHRESRRL 863
>HAPIP_HUMAN (O60229) Huntingtin-associated protein-interacting protein (Protein| Duo) Length = 1663 Score = 31.2 bits (69), Expect = 2.6 Identities = 29/122 (23%), Positives = 57/122 (46%), Gaps = 8/122 (6%) Frame = -1 Query: 548 LNDHTLAYQSRVGPVQWLKPYTD-EVLVELGQKGVKSLLAVPVSFVSE-HIETLE----- 390 L+ HT ++ + LK Y + V + ++ VK L+ + SFV + HI E Sbjct: 1154 LSTHTSTGETTEETQELLKEYGEFRVPAKQTKEKVKLLIQLADSFVEKGHIHATEIRKWV 1213 Query: 389 -EIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVEALPSASAMATRKVKDTDSD 213 +D YR+ +L G + ALG + D D ++ +P++ + K++D + + Sbjct: 1214 TTVDKHYRDFSLRMGKYRYSLEKALGVNT---EDNKDLELDIIPASLSDREVKLRDANHE 1270 Query: 212 MD 207 ++ Sbjct: 1271 VN 1272
>EFG_RHILO (Q98N59) Elongation factor G (EF-G)| Length = 696 Score = 31.2 bits (69), Expect = 2.6 Identities = 31/113 (27%), Positives = 51/113 (45%), Gaps = 23/113 (20%) Frame = -1 Query: 410 EHIETLEEIDMEYRELALESGIENWGRVPA-------------------LGCTSSF---- 300 E+ E + E +E E ALE+ +E G++P+ + C S+F Sbjct: 215 EYREKMIEAAVEMDETALENYLE--GKMPSNDEIRSLIRKGTIAVKFFPMFCGSAFKNKG 272 Query: 299 ISDLADAVVEALPSASAMATRKVKDTDSDMDMMHYLTKMFLGSVLAFFLLLSP 141 + L DAVVE LPS + + K D +D ++ + S+LAF ++ P Sbjct: 273 VQPLLDAVVEYLPSPADVPAIKGVDAKTDAEIERHAVDDEPLSMLAFKIMNDP 325
>DPO3_MYCPU (P47729) DNA polymerase III polC-type (EC 2.7.7.7) (PolIII)| Length = 1435 Score = 31.2 bits (69), Expect = 2.6 Identities = 16/50 (32%), Positives = 30/50 (60%), Gaps = 1/50 (2%) Frame = -1 Query: 482 DEVLVELGQKGVKSLLAVPVSF-VSEHIETLEEIDMEYRELALESGIENW 336 D+++V+L +KGV + +SF + E + + + +E + +E GIENW Sbjct: 1198 DDIMVDLIKKGVP----IDLSFTIMEQVRKGKGLSLEQKRKLIEHGIENW 1243
>TARSH_HUMAN (Q7Z7G0) Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding| protein) (NeshBP) (ABI gene family member 3-binding protein) Length = 1075 Score = 30.8 bits (68), Expect = 3.4 Identities = 16/52 (30%), Positives = 21/52 (40%), Gaps = 2/52 (3%) Frame = -2 Query: 310 PHPSSRTSL--TLSSKPFPLPPRWRPERSRXXXXXXXXXXX*PRCSWARSWP 161 P P TS+ T +P P PPR +PER+ P +W P Sbjct: 458 PAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKISKSPEPTWTTPAP 509
>HAPIP_RAT (P97924) Huntingtin-associated protein-interacting protein (Protein| Duo) (Kalirin) (PAM COOH-terminal interactor protein 10) (P-CIP10) Length = 1919 Score = 30.4 bits (67), Expect = 4.4 Identities = 29/122 (23%), Positives = 57/122 (46%), Gaps = 8/122 (6%) Frame = -1 Query: 548 LNDHTLAYQSRVGPVQWLKPYTD-EVLVELGQKGVKSLLAVPVSFVSE-HIETLE----- 390 L+ HT ++ + LK Y + V + ++ VK L+ + SFV + HI E Sbjct: 1147 LSTHTSTGETTEETQELLKEYGEFRVPAKQTKEKVKLLIQLADSFVEKGHIHATEIRKWV 1206 Query: 389 -EIDMEYRELALESGIENWGRVPALGCTSSFISDLADAVVEALPSASAMATRKVKDTDSD 213 +D YR+ +L G + ALG + D D ++ +P++ + K++D + + Sbjct: 1207 TTVDKHYRDFSLRMGKYRYTLEKALGVNT---EDNKDLELDIIPASLSDREVKLRDANHE 1263 Query: 212 MD 207 ++ Sbjct: 1264 VN 1265
>PRIM_STAAU (O05338) DNA primase (EC 2.7.7.-)| Length = 605 Score = 30.4 bits (67), Expect = 4.4 Identities = 13/52 (25%), Positives = 30/52 (57%) Frame = -1 Query: 620 GDPYRDQMEDCIALIMEELKSRGTLNDHTLAYQSRVGPVQWLKPYTDEVLVE 465 G+PY ++++D + +I E+ + +H L +R+G V+ K Y +++ + Sbjct: 549 GEPYENEIDDYVNVINEKGQETIESLNHKLREATRIGDVELQKYYLQQIVAK 600
>EFG_CLOAB (Q97EH4) Elongation factor G (EF-G)| Length = 687 Score = 30.4 bits (67), Expect = 4.4 Identities = 25/85 (29%), Positives = 43/85 (50%), Gaps = 4/85 (4%) Frame = -1 Query: 449 VKSLLAVPVSFVSEHIETLEEIDMEYRELALESGIENWGRVPALGCTSSF----ISDLAD 282 +++++ + +++++E EEI +E AL G+ VP C SS+ + + D Sbjct: 215 IEAIVELDEELMNKYLEG-EEISVEEINAALRKGVIANEIVPVT-CGSSYKNKGVQQMLD 272 Query: 281 AVVEALPSASAMATRKVKDTDSDMD 207 AVVE LPS + K D D + D Sbjct: 273 AVVEYLPSPLDIPPVKGVDEDGNDD 297
>QUEA_BACHK (Q6HDA8) S-adenosylmethionine:tRNA ribosyltransferase-isomerase (EC| 5.-.-.-) (Queuosine biosynthesis protein queA) Length = 350 Score = 29.6 bits (65), Expect = 7.5 Identities = 24/80 (30%), Positives = 42/80 (52%), Gaps = 18/80 (22%) Frame = -1 Query: 488 YTDEVLVELGQKGVKSLLAVPVSFVSEHI----------ETLEEIDM--EYRELALESGI 345 +T+E+L +L QKGV+ ++F++ H+ +T+EE M EY ++ E+ Sbjct: 184 FTEELLEKLKQKGVE------LAFITLHVGLGTFRPVSADTIEEHHMHAEYYHMSEETAA 237 Query: 344 ------ENWGRVPALGCTSS 303 EN GR+ +G TS+ Sbjct: 238 LLNRVKENGGRIITVGTTST 257
>QUEA_BACCZ (Q634C6) S-adenosylmethionine:tRNA ribosyltransferase-isomerase (EC| 5.-.-.-) (Queuosine biosynthesis protein queA) Length = 350 Score = 29.6 bits (65), Expect = 7.5 Identities = 24/80 (30%), Positives = 42/80 (52%), Gaps = 18/80 (22%) Frame = -1 Query: 488 YTDEVLVELGQKGVKSLLAVPVSFVSEHI----------ETLEEIDM--EYRELALESGI 345 +T+E+L +L QKGV+ ++F++ H+ +T+EE M EY ++ E+ Sbjct: 184 FTEELLEKLKQKGVE------LAFITLHVGLGTFRPVSADTIEEHHMHAEYYHMSEETAA 237 Query: 344 ------ENWGRVPALGCTSS 303 EN GR+ +G TS+ Sbjct: 238 LLNRVKENGGRIITVGTTST 257
>QUEA_BACC1 (Q730B3) S-adenosylmethionine:tRNA ribosyltransferase-isomerase (EC| 5.-.-.-) (Queuosine biosynthesis protein queA) Length = 350 Score = 29.6 bits (65), Expect = 7.5 Identities = 24/80 (30%), Positives = 42/80 (52%), Gaps = 18/80 (22%) Frame = -1 Query: 488 YTDEVLVELGQKGVKSLLAVPVSFVSEHI----------ETLEEIDM--EYRELALESGI 345 +T+E+L +L QKGV+ ++F++ H+ +T+EE M EY ++ E+ Sbjct: 184 FTEELLEKLKQKGVE------LAFITLHVGLGTFRPVSADTIEEHHMHAEYYHMSEETAA 237 Query: 344 ------ENWGRVPALGCTSS 303 EN GR+ +G TS+ Sbjct: 238 LLNRVKENGGRIITVGTTST 257
>QUEA_BACAN (Q81LH1) S-adenosylmethionine:tRNA ribosyltransferase-isomerase (EC| 5.-.-.-) (Queuosine biosynthesis protein queA) Length = 350 Score = 29.6 bits (65), Expect = 7.5 Identities = 24/80 (30%), Positives = 42/80 (52%), Gaps = 18/80 (22%) Frame = -1 Query: 488 YTDEVLVELGQKGVKSLLAVPVSFVSEHI----------ETLEEIDM--EYRELALESGI 345 +T+E+L +L QKGV+ ++F++ H+ +T+EE M EY ++ E+ Sbjct: 184 FTEELLEKLKQKGVE------LAFITLHVGLGTFRPVSADTIEEHHMHAEYYHMSEETAA 237 Query: 344 ------ENWGRVPALGCTSS 303 EN GR+ +G TS+ Sbjct: 238 LLNRVKENGGRIITVGTTST 257
>P53_MARMO (O36006) Cellular tumor antigen p53 (Tumor suppressor p53)| Length = 391 Score = 29.6 bits (65), Expect = 7.5 Identities = 19/62 (30%), Positives = 32/62 (51%) Frame = +2 Query: 44 MVSSYNHQNG*PRCIDKNKQLTEECSGKQKLASAITAGRRPGPSPRTSWSDNASCPCQSQ 223 ++SS + +N + D+ Q++ + K +A T PSP TSW ++S P Q+ Sbjct: 44 LLSSEDVENWFDKGPDEALQMSAAPAPKAPTPAASTLA---APSPATSWPLSSSVPSQNT 100 Query: 224 YP 229 YP Sbjct: 101 YP 102
>NXF1_CAEEL (Q9XVS7) Nuclear RNA export factor 1| Length = 628 Score = 29.3 bits (64), Expect = 9.8 Identities = 13/33 (39%), Positives = 18/33 (54%) Frame = +3 Query: 207 VHVRVSILDLSGRHRGGRGKGFDDSVSEVRDEG 305 V VR S+ S R RGG +GF S + + + G Sbjct: 60 VPVRASLTSASSRGRGGSSRGFGQSAASIANTG 92 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 89,733,046 Number of Sequences: 219361 Number of extensions: 1803656 Number of successful extensions: 5477 Number of sequences better than 10.0: 154 Number of HSP's better than 10.0 without gapping: 5254 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5426 length of database: 80,573,946 effective HSP length: 107 effective length of database: 57,102,319 effective search space used: 5653129581 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
