ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | FLbaf124d14 |
|---|---|
| Clone Library Name | barley_pub |
>Q3UXZ9:JAD1A_MOUSE Histone demethylase JARID1A - Mus musculus (Mouse)| Length = 1690 Score = 328 bits (842), Expect = 9e-89 Identities = 182/430 (42%), Positives = 239/430 (55%), Gaps = 5/430 (1%) Frame = +2 Query: 1082 FGFEPGP-ELTLQKFQKYADYFSEQYFKKDASMNSLPSVEDIEGEYWRIVESPTEEIEVI 1258 FGFE E TLQ F + AD F YF M +P+ E +E E+WR+V S E++ V Sbjct: 352 FGFEQAVREYTLQSFGEMADNFKSDYFNMPVHM--VPT-ELVEKEFWRLVSSIEEDVIVE 408 Query: 1259 YGADLETGSFGSGFPKLPPETKS-DIEDKYAHSGWNLNNLPRLQGSVLSFEGGDISGVLV 1435 YGAD+ + FGSGFPK + K E++YA SGWNLNN+P L+ SVL+ DISG+ V Sbjct: 409 YGADISSKDFGSGFPKKDGQRKMLPEEEEYALSGWNLNNMPVLEQSVLAHINVDISGMKV 468 Query: 1436 PWVYVGMCFSSFCWHVEDHHLYSLNYLHWGAPKMWYGVPGKDAVNLESAMRKHLPDLFEE 1615 PW+YVGMCFSSFCWH+EDH YS+NYLHWG PK WYGVP A LE MR+ P+LFE Sbjct: 469 PWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPSHAAEQLEEVMRELAPELFES 528 Query: 1616 QPDLLHNLVTQFSPSLLKSEGVQAYRCVQREGEFVLTFPRAYHAGFNCGFNCAEAVNVAP 1795 QPDLLH LVT +P++L GV YR Q GEFV+TFPRAYH+GFN G+N AEAVN Sbjct: 529 QPDLLHQLVTIMNPNVLMEHGVPVYRTNQCAGEFVVTFPRAYHSGFNQGYNFAEAVNFCT 588 Query: 1796 IDWLPVGQNAVELYREQARKITVSHDKLLLGAAREAIRAQWDILFLKRNTADNLRWKSVC 1975 DWLP+G+ V YR R SH++L+ A + Sbjct: 589 ADWLPIGRQCVNHYRRLRRHCVFSHEELIFKMAADPECLD-------------------V 629 Query: 1976 GPDSTICKSLKARIETELAQRQNLCSPSQSRKMDAEFD---SADRECAFCYYDLHLSASG 2146 G + +CK L E E R+++ + F+ +R+C+ C LSA Sbjct: 630 GLAAMVCKELTLMTEEETRLRESVVQMGVVMSEEEVFELVPDDERQCSACRTTCFLSALT 689 Query: 2147 CPCCPEKYACLLHAKQLCSCDWDKRFFLFRYDVNELNILADALGGKLSAVHRWGVSDLGL 2326 C C PE+ CL H LCSC + +RY + +L L + + + W V+ + Sbjct: 690 CSCNPERLVCLYHPTDLCSCPMQNKCLRYRYPLEDLPSLLYGVKVRAQSYDTW-VNRVTE 748 Query: 2327 SLSSCVKREK 2356 +LS+ +K Sbjct: 749 ALSASFNHKK 758 Score = 63.2 bits (152), Expect = 1e-08 Identities = 32/71 (45%), Positives = 44/71 (61%) Frame = +2 Query: 791 EAPVFHPTEEEFKDTLKYIESIRPTAEPYGICRIVPPPSWKPPCLLKEKSTWENSTFSTR 970 E PVF P+ EEF D L +I IRP AE GIC+I PP W+PP + K+ F+ R Sbjct: 18 ECPVFEPSWEEFTDPLSFIGRIRPFAEKTGICKIRPPKDWQPPFACEVKT----FRFTPR 73 Query: 971 VQKVDKLQNRT 1003 VQ++++L+ T Sbjct: 74 VQRLNELEAMT 84
>P29375:JAD1A_HUMAN Histone demethylase JARID1A - Homo sapiens (Human)| Length = 1722 Score = 328 bits (841), Expect = 1e-88 Identities = 198/499 (39%), Positives = 261/499 (52%), Gaps = 21/499 (4%) Frame = +2 Query: 1055 SEPEENSKRFGFEPGP-ELTLQKFQKYADYFSEQYFKKDASMNSLPSVEDIEGEYWRIVE 1231 S+P E FGFE E TLQ F + AD F YF M +P+ E +E E+WR+V Sbjct: 346 SKPRE---AFGFEQAVREYTLQSFGEMADNFKSDYFNMPVHM--VPT-ELVEKEFWRLVS 399 Query: 1232 SPTEEIEVIYGADLETGSFGSGFP------KLPPETKSDIEDKYAHSGWNLNNLPRLQGS 1393 S E++ V YGAD+ + FGSGFP K+ PE E++YA SGWNLNN+P L+ S Sbjct: 400 SIEEDVIVEYGADISSKDFGSGFPVKDGRRKILPE-----EEEYALSGWNLNNMPVLEQS 454 Query: 1394 VLSFEGGDISGVLVPWVYVGMCFSSFCWHVEDHHLYSLNYLHWGAPKMWYGVPGKDAVNL 1573 VL+ DISG+ VPW+YVGMCFSSFCWH+EDH YS+NYLHWG PK WYGVP A L Sbjct: 455 VLAHINVDISGMKVPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPSHAAEQL 514 Query: 1574 ESAMRKHLPDLFEEQPDLLHNLVTQFSPSLLKSEGVQAYRCVQREGEFVLTFPRAYHAGF 1753 E MR+ P+LFE QPDLLH LVT +P++L GV YR Q GEFV+TFPRAYH+GF Sbjct: 515 EEVMRELAPELFESQPDLLHQLVTIMNPNVLMEHGVPVYRTNQCAGEFVVTFPRAYHSGF 574 Query: 1754 NCGFNCAEAVNVAPIDWLPVGQNAVELYREQARKITVSHDKLLLGAAREAIRAQWDILFL 1933 N G+N AEAVN DWLP+G+ V YR R SH++L+ A + Sbjct: 575 NQGYNFAEAVNFCTADWLPIGRQCVNHYRRLRRHCVFSHEELIFKMAADPECLD------ 628 Query: 1934 KRNTADNLRWKSVCGPDSTICKSLKARIETELAQRQNLCSPSQSRKMDAEFD---SADRE 2104 G + +CK L E E R+++ + F+ +R+ Sbjct: 629 -------------VGLAAMVCKELTLMTEEETRLRESVVQMGVLMSEEEVFELVPDDERQ 675 Query: 2105 CAFCYYDLHLSASGCPCCPEKYACLLHAKQLCSCDWDKRFFLFRYDVNELNILADALGGK 2284 C+ C LSA C C PE+ CL H LC C K+ +RY + +L L + + Sbjct: 676 CSACRTTCFLSALTCSCNPERLVCLYHPTDLCPCPMQKKCLRYRYPLEDLPSLLYGVKVR 735 Query: 2285 LSAVHRWGVSDLGLSLSS-----------CVKREKVQDSKTVRRSTDGPRRSYMSQASTV 2431 + W VS + +LS+ V E +D K R + +A T Sbjct: 736 AQSYDTW-VSRVTEALSANFNHKKDLIELRVMLEDAEDRKYPENDLFRKLRDAVKEAETC 794 Query: 2432 SLVPSLACNEQKDKENKMP 2488 + V L + +K K + P Sbjct: 795 ASVAQLLLS-KKQKHRQSP 812 Score = 64.7 bits (156), Expect = 3e-09 Identities = 33/71 (46%), Positives = 44/71 (61%) Frame = +2 Query: 791 EAPVFHPTEEEFKDTLKYIESIRPTAEPYGICRIVPPPSWKPPCLLKEKSTWENSTFSTR 970 E PVF P+ EEF D L +I IRP AE GIC+I PP W+PP + KS F+ R Sbjct: 18 ECPVFEPSWEEFTDPLSFIGRIRPLAEKTGICKIRPPKDWQPPFACEVKS----FRFTPR 73 Query: 971 VQKVDKLQNRT 1003 VQ++++L+ T Sbjct: 74 VQRLNELEAMT 84
>Q9UGL1:JAD1B_HUMAN Histone demethylase JARID1B - Homo sapiens (Human)| Length = 1544 Score = 326 bits (836), Expect = 5e-88 Identities = 185/433 (42%), Positives = 250/433 (57%), Gaps = 10/433 (2%) Frame = +2 Query: 1046 RKLSEPEENSKRFGFEPGP-ELTLQKFQKYADYFSEQYFKKDASMNSLPSVEDIEGEYWR 1222 ++ S+P+E FGFE + TL+ F + AD F YF M +P+ E +E E+WR Sbjct: 359 QECSKPQE---AFGFEQAARDYTLRTFGEMADAFKSDYFNMPVHM--VPT-ELVEKEFWR 412 Query: 1223 IVESPTEEIEVIYGADLETGSFGSGFP------KLPPETKSDIEDKYAHSGWNLNNLPRL 1384 +V + E++ V YGAD+ + FGSGFP KL PE E++Y SGWNLNN+P + Sbjct: 413 LVSTIEEDVTVEYGADIASKEFGSGFPVRDGKIKLSPE-----EEEYLDSGWNLNNMPVM 467 Query: 1385 QGSVLSFEGGDISGVLVPWVYVGMCFSSFCWHVEDHHLYSLNYLHWGAPKMWYGVPGKDA 1564 + SVL+ DI G+ +PW+YVGMCFSSFCWH+EDH YS+NYLHWG PK WYGVPG A Sbjct: 468 EQSVLAHITADICGMKLPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPGYAA 527 Query: 1565 VNLESAMRKHLPDLFEEQPDLLHNLVTQFSPSLLKSEGVQAYRCVQREGEFVLTFPRAYH 1744 LE+ M+K P+LF QPDLLH LVT +P+ L + V YR Q GEFV+TFPRAYH Sbjct: 528 EQLENVMKKLAPELFVSQPDLLHQLVTIMNPNTLMTHEVPVYRTNQCAGEFVITFPRAYH 587 Query: 1745 AGFNCGFNCAEAVNVAPIDWLPVGQNAVELYREQARKITVSHDKLLLGAAREAIRAQWDI 1924 +GFN GFN AEAVN +DWLP+G+ VE YR R SHD+++ A +A D+ Sbjct: 588 SGFNQGFNFAEAVNFCTVDWLPLGRQCVEHYRLLHRYCVFSHDEMICKMASKA-----DV 642 Query: 1925 LFLKRNTADNLRWKSVCGPDSTICKSLKARIETELAQRQNL--CSPSQSRKMDAE-FDSA 2095 L + ST+ K + IE E A R+ + S +MD E Sbjct: 643 LDVV--------------VASTVQKDMAIMIEDEKALRETVRKLGVIDSERMDFELLPDD 688 Query: 2096 DRECAFCYYDLHLSASGCPCCPEKYACLLHAKQLCSCDWDKRFFLFRYDVNELNILADAL 2275 +R+C C +SA C C P CL H K+LCSC K +RY +++L + +AL Sbjct: 689 ERQCVKCKTTCFMSAISCSCKPGLLVCLHHVKELCSCPPYKYKLRYRYTLDDLYPMMNAL 748 Query: 2276 GGKLSAVHRWGVS 2314 + + + W ++ Sbjct: 749 KLRAESYNEWALN 761 Score = 63.9 bits (154), Expect = 6e-09 Identities = 30/74 (40%), Positives = 44/74 (59%) Frame = +2 Query: 791 EAPVFHPTEEEFKDTLKYIESIRPTAEPYGICRIVPPPSWKPPCLLKEKSTWENSTFSTR 970 E PVF P+ EEF D +I IRP AE GIC++ PPP W+PP + F+ R Sbjct: 31 ECPVFEPSWEEFADPFAFIHKIRPIAEQTGICKVRPPPDWQPPFACDV----DKLHFTPR 86 Query: 971 VQKVDKLQNRTSSK 1012 +Q++++L+ +T K Sbjct: 87 IQRLNELEAQTRVK 100
>Q80Y84:JAD1B_MOUSE Histone demethylase JARID1B - Mus musculus (Mouse)| Length = 1544 Score = 324 bits (831), Expect = 2e-87 Identities = 182/428 (42%), Positives = 249/428 (58%), Gaps = 5/428 (1%) Frame = +2 Query: 1046 RKLSEPEENSKRFGFEPGP-ELTLQKFQKYADYFSEQYFKKDASMNSLPSVEDIEGEYWR 1222 ++ ++P+E FGFE + TL+ F + AD F YF M +P+ E +E E+WR Sbjct: 359 QECNKPQE---AFGFEQAARDYTLRTFGEMADAFKSDYFNMPVHM--VPT-ELVEKEFWR 412 Query: 1223 IVESPTEEIEVIYGADLETGSFGSGFPKLPPETK-SDIEDKYAHSGWNLNNLPRLQGSVL 1399 +V + E++ V YGAD+ + FGSGFP + K S E++Y SGWNLNN+P ++ SVL Sbjct: 413 LVSTIEEDVTVEYGADIASKEFGSGFPVRDGKIKISPEEEEYLDSGWNLNNMPVMEQSVL 472 Query: 1400 SFEGGDISGVLVPWVYVGMCFSSFCWHVEDHHLYSLNYLHWGAPKMWYGVPGKDAVNLES 1579 + DI G+ +PW+YVGMCFSSFCWH+EDH YS+NYLHWG PK WYGVPG A LE+ Sbjct: 473 AHITADICGMKLPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPGYAAEQLEN 532 Query: 1580 AMRKHLPDLFEEQPDLLHNLVTQFSPSLLKSEGVQAYRCVQREGEFVLTFPRAYHAGFNC 1759 M+K P+LF QPDLLH LVT +P+ L + V YR Q GEFV+TFPRAYH+GFN Sbjct: 533 VMKKLAPELFVSQPDLLHQLVTIMNPNTLMTHEVPVYRTNQCAGEFVITFPRAYHSGFNQ 592 Query: 1760 GFNCAEAVNVAPIDWLPVGQNAVELYREQARKITVSHDKLLLGAAREAIRAQWDILFLKR 1939 GFN AEAVN +DWLP+G+ VE YR R SHD+++ A +A D+L + Sbjct: 593 GFNFAEAVNFCTVDWLPLGRQCVEHYRLLHRYCVFSHDEMICKMASKA-----DVLDVV- 646 Query: 1940 NTADNLRWKSVCGPDSTICKSLKARIETELAQRQNL--CSPSQSRKMDAE-FDSADRECA 2110 ST+ K + IE E A R+ + S +MD E +R+C Sbjct: 647 -------------VASTVQKDMAIMIEDEKALRETVRKLGVIDSERMDFELLPDDERQCI 693 Query: 2111 FCYYDLHLSASGCPCCPEKYACLLHAKQLCSCDWDKRFFLFRYDVNELNILADALGGKLS 2290 C +SA C C P CL H K+LCSC K +RY +++L + +AL + Sbjct: 694 KCKTTCFMSAISCSCKPGLLVCLHHVKELCSCPPYKYNLRYRYTLDDLYPMMNALKLRAE 753 Query: 2291 AVHRWGVS 2314 + + W ++ Sbjct: 754 SYNEWALN 761 Score = 63.9 bits (154), Expect = 6e-09 Identities = 30/74 (40%), Positives = 44/74 (59%) Frame = +2 Query: 791 EAPVFHPTEEEFKDTLKYIESIRPTAEPYGICRIVPPPSWKPPCLLKEKSTWENSTFSTR 970 E PVF P+ EEF D +I IRP AE GIC++ PPP W+PP + F+ R Sbjct: 31 ECPVFEPSWEEFADPFAFIHKIRPIAEQTGICKVRPPPDWQPPFACDV----DKLHFTPR 86 Query: 971 VQKVDKLQNRTSSK 1012 +Q++++L+ +T K Sbjct: 87 IQRLNELEAQTRVK 100
>Q5F3R2:JAD1B_CHICK Histone demethylase JARID1B - Gallus gallus (Chicken)| Length = 1522 Score = 323 bits (827), Expect = 5e-87 Identities = 182/430 (42%), Positives = 244/430 (56%), Gaps = 10/430 (2%) Frame = +2 Query: 1046 RKLSEPEENSKRFGFEPGP-ELTLQKFQKYADYFSEQYFKKDASMNSLPSVEDIEGEYWR 1222 ++ ++P+E FGFE + TL+ F + AD F YF M +P+ E +E E+WR Sbjct: 334 QECNKPQE---AFGFEQAARDYTLRTFGEMADAFKSDYFNMPVHM--VPT-ELVEKEFWR 387 Query: 1223 IVESPTEEIEVIYGADLETGSFGSGFP------KLPPETKSDIEDKYAHSGWNLNNLPRL 1384 +V + E++ V YGAD+ + FGSGFP K+ PE E++Y SGWNLNN+P + Sbjct: 388 LVSTIEEDVTVEYGADIASKEFGSGFPVRDGKFKVRPE-----EEEYLDSGWNLNNMPVM 442 Query: 1385 QGSVLSFEGGDISGVLVPWVYVGMCFSSFCWHVEDHHLYSLNYLHWGAPKMWYGVPGKDA 1564 + SVL+ DI G+ +PW+YVGMCFSSFCWH+EDH YS+NYLHWG PK WYG PG A Sbjct: 443 EQSVLAHITADICGMKLPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGAPGYAA 502 Query: 1565 VNLESAMRKHLPDLFEEQPDLLHNLVTQFSPSLLKSEGVQAYRCVQREGEFVLTFPRAYH 1744 LE M+K P+LFE QPDLLH LVT +P+ L + GV YR Q GEFV+TFPRAYH Sbjct: 503 EQLEDVMKKLAPELFESQPDLLHQLVTIMNPNTLMAHGVPVYRTNQCAGEFVITFPRAYH 562 Query: 1745 AGFNCGFNCAEAVNVAPIDWLPVGQNAVELYREQARKITVSHDKLLLGAAREAIRAQWDI 1924 +GFN GFN AEAVN +DWLP+G+ +E YR +R SHD+++ A +A DI Sbjct: 563 SGFNQGFNFAEAVNFCTVDWLPLGRQCIEHYRLLSRYCVFSHDEMICKMASKA-----DI 617 Query: 1925 LFLKRNTADNLRWKSVCGPDSTICKSLKARIETELAQR---QNLCSPSQSRKMDAEFDSA 2095 L + ST+ K + I+ E R Q L R F Sbjct: 618 LDVV--------------VASTVQKDMAIMIDDEKMLREKVQKLGVTDSERVAFELFPDD 663 Query: 2096 DRECAFCYYDLHLSASGCPCCPEKYACLLHAKQLCSCDWDKRFFLFRYDVNELNILADAL 2275 +R+C C +SA CPC P CL H + LCSC + +RY + EL + +AL Sbjct: 664 ERQCYKCKTTCFMSAVYCPCKPGLLVCLYHVEDLCSCPTYQYKLGYRYTLEELYPMMNAL 723 Query: 2276 GGKLSAVHRW 2305 + + + W Sbjct: 724 KMRAESYNEW 733 Score = 63.9 bits (154), Expect = 6e-09 Identities = 30/74 (40%), Positives = 44/74 (59%) Frame = +2 Query: 791 EAPVFHPTEEEFKDTLKYIESIRPTAEPYGICRIVPPPSWKPPCLLKEKSTWENSTFSTR 970 E PVF P+ EEF D +I IRP AE GIC++ PPP W+PP + F+ R Sbjct: 9 ECPVFEPSWEEFADPFAFIHKIRPIAEQTGICKVRPPPDWQPPFACDV----DKLHFTPR 64 Query: 971 VQKVDKLQNRTSSK 1012 +Q++++L+ +T K Sbjct: 65 IQRLNELEAQTRVK 78
>Q9VMJ7:JAD1_DROME Histone demethylase lid - Drosophila melanogaster (Fruit fly)| Length = 1838 Score = 321 bits (823), Expect = 1e-86 Identities = 179/429 (41%), Positives = 237/429 (55%), Gaps = 10/429 (2%) Frame = +2 Query: 1049 KLSEPEENSKRFGFEPGP-ELTLQKFQKYADYFSEQYFKKDASMNSLPSVEDIEGEYWRI 1225 ++S+P+E FGFE E TLQ+F + AD F ++YF+K L E +E E+WRI Sbjct: 499 EVSKPQE---AFGFEQAEREYTLQQFGQMADQFKQEYFRKPVH---LVPTEMVEREFWRI 552 Query: 1226 VESPTEEIEVIYGADLETGSFGSGFPKLPPETKSDI-----EDKYAHSGWNLNNLPRLQG 1390 V S E++ V YGADL T GSGFP TKS + + +YA S WNLNNLP L+ Sbjct: 553 VSSIDEDVTVEYGADLHTMDHGSGFP-----TKSSLYLLPGDQEYAESSWNLNNLPLLED 607 Query: 1391 SVLSFEGGDISGVLVPWVYVGMCFSSFCWHVEDHHLYSLNYLHWGAPKMWYGVPGKDAVN 1570 S+L DISG+ PW+YVGMCF++FCWH EDH YS+NYLHWG PK WYGVPG A Sbjct: 608 SILGHINADISGMNAPWMYVGMCFAAFCWHNEDHWSYSINYLHWGEPKTWYGVPGSCAEQ 667 Query: 1571 LESAMRKHLPDLFEEQPDLLHNLVTQFSPSLLKSEGVQAYRCVQREGEFVLTFPRAYHAG 1750 E M++ P+LF QPDLLH LVT +P++L + V +R Q GEFV+TFPRAYHAG Sbjct: 668 FEETMKQAAPELFSSQPDLLHQLVTIMNPNILMNNRVPVFRTDQHAGEFVITFPRAYHAG 727 Query: 1751 FNCGFNCAEAVNVAPIDWLPVGQNAVELYREQARKITVSHDKLLLGAAREAIRAQWDILF 1930 FN G+N AEAVN AP DWL +G+ V Y R SHD+L+ A E + + I Sbjct: 728 FNQGYNFAEAVNFAPADWLKMGRECVNHYSMLRRFCVFSHDELVCKMALEPAKLTFGI-- 785 Query: 1931 LKRNTADNLRWKSVCGPDSTICK-SLKARIETELAQRQNLCSPSQSRKMDAEFD---SAD 2098 +T C + ++TE R++L +R F+ + Sbjct: 786 ------------------ATACYIDMAEMVDTEKKLRKSLLEWGVTRAERRAFELVNDDE 827 Query: 2099 RECAFCYYDLHLSASGCPCCPEKYACLLHAKQLCSCDWDKRFFLFRYDVNELNILADALG 2278 R C C LSA C C + CL H LC C +K ++RY ++E+ ++ L Sbjct: 828 RHCQECNTTCFLSAVACECNDKLIVCLRHYTVLCGCAPEKHTLIYRYTLDEMPLMLQKLK 887 Query: 2279 GKLSAVHRW 2305 K + RW Sbjct: 888 VKAHSFERW 896 Score = 62.8 bits (151), Expect = 1e-08 Identities = 32/74 (43%), Positives = 44/74 (59%) Frame = +2 Query: 791 EAPVFHPTEEEFKDTLKYIESIRPTAEPYGICRIVPPPSWKPPCLLKEKSTWENSTFSTR 970 E PVF PT EEFK+ L YI IR AE GI +I+PP +W PP + + F R Sbjct: 160 ECPVFRPTTEEFKNPLAYISKIRSIAEKCGIAKILPPATWSPPFAVDV----DKLRFVPR 215 Query: 971 VQKVDKLQNRTSSK 1012 VQ++++L+ +T K Sbjct: 216 VQRLNELEAKTRVK 229
>P41230:JAD1C_MOUSE Histone demethylase JARID1C - Mus musculus (Mouse)| Length = 1554 Score = 310 bits (794), Expect = 3e-83 Identities = 176/428 (41%), Positives = 235/428 (54%), Gaps = 10/428 (2%) Frame = +2 Query: 1052 LSEPEENSKRFGFEPGP-ELTLQKFQKYADYFSEQYFKKDASMNSLPSVEDIEGEYWRIV 1228 ++E + + FGFE E TLQ F + AD F YF M +P+ E +E E+WR+V Sbjct: 373 MAECKRPPEAFGFEQATREYTLQSFGEMADSFKADYFNMPVHM--VPT-ELVEKEFWRLV 429 Query: 1229 ESPTEEIEVIYGADLETGSFGSGFP------KLPPETKSDIEDKYAHSGWNLNNLPRLQG 1390 S E++ V YGAD+ + FGSGFP L PE E++YA SGWNLN +P L+ Sbjct: 430 NSIEEDVTVEYGADIHSKEFGSGFPVSDSKRHLTPE-----EEEYATSGWNLNVMPVLEQ 484 Query: 1391 SVLSFEGGDISGVLVPWVYVGMCFSSFCWHVEDHHLYSLNYLHWGAPKMWYGVPGKDAVN 1570 SVL DISG+ VPW+YVGM FS+FCWH+EDH YS+NYLHWG PK WYGVP A + Sbjct: 485 SVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSLAAEH 544 Query: 1571 LESAMRKHLPDLFEEQPDLLHNLVTQFSPSLLKSEGVQAYRCVQREGEFVLTFPRAYHAG 1750 LE M+K P+LF+ QPDLLH LVT +P+ L S GV R Q GEFV+TFPRAYH+G Sbjct: 545 LEEVMKKLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEFVITFPRAYHSG 604 Query: 1751 FNCGFNCAEAVNVAPIDWLPVGQNAVELYREQARKITVSHDKLLLGAAREAIRAQWDILF 1930 FN G+N AEAVN DWLP G+ +E YR R SH++L+ A A + D+ Sbjct: 605 FNQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRYCVFSHEELICKMA--ACPEKLDL-- 660 Query: 1931 LKRNTADNLRWKSVCGPDSTICKSLKARIETELAQRQNLCSPSQSRKMDAEFD---SADR 2101 N A + + K + ++ E R+ L + F+ +R Sbjct: 661 ---NLA------------AAVHKEMFIMVQEERRLRKALLEKGITEAEREAFELLPDDER 705 Query: 2102 ECAFCYYDLHLSASGCPCCPEKYACLLHAKQLCSCDWDKRFFLFRYDVNELNILADALGG 2281 +C C LSA C CP+ CL H LC C +++ +RY ++EL + L Sbjct: 706 QCIKCKTTCFLSALACYDCPDGLVCLSHINDLCKCSSSRQYLRYRYTLDELPAMLHKLKV 765 Query: 2282 KLSAVHRW 2305 + + W Sbjct: 766 RAESFDTW 773 Score = 66.6 bits (161), Expect = 9e-10 Identities = 32/74 (43%), Positives = 47/74 (63%) Frame = +2 Query: 791 EAPVFHPTEEEFKDTLKYIESIRPTAEPYGICRIVPPPSWKPPCLLKEKSTWENSTFSTR 970 E PVF P+ EF+D L YI IRP AE GIC+I PP W+PP ++ +N F+ R Sbjct: 13 ECPVFEPSWAEFRDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEV----DNFRFTPR 68 Query: 971 VQKVDKLQNRTSSK 1012 +Q++++L+ +T K Sbjct: 69 IQRLNELEAQTRVK 82
>P41229:JAD1C_HUMAN Histone demethylase JARID1C - Homo sapiens (Human)| Length = 1560 Score = 310 bits (794), Expect = 3e-83 Identities = 176/428 (41%), Positives = 235/428 (54%), Gaps = 10/428 (2%) Frame = +2 Query: 1052 LSEPEENSKRFGFEPGP-ELTLQKFQKYADYFSEQYFKKDASMNSLPSVEDIEGEYWRIV 1228 ++E + + FGFE E TLQ F + AD F YF M +P+ E +E E+WR+V Sbjct: 373 MAECKRPPEAFGFEQATREYTLQSFGEMADSFKADYFNMPVHM--VPT-ELVEKEFWRLV 429 Query: 1229 ESPTEEIEVIYGADLETGSFGSGFP------KLPPETKSDIEDKYAHSGWNLNNLPRLQG 1390 S E++ V YGAD+ + FGSGFP L PE E++YA SGWNLN +P L+ Sbjct: 430 NSIEEDVTVEYGADIHSKEFGSGFPVSDSKRHLTPE-----EEEYATSGWNLNVMPVLEQ 484 Query: 1391 SVLSFEGGDISGVLVPWVYVGMCFSSFCWHVEDHHLYSLNYLHWGAPKMWYGVPGKDAVN 1570 SVL DISG+ VPW+YVGM FS+FCWH+EDH YS+NYLHWG PK WYGVP A + Sbjct: 485 SVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSLAAEH 544 Query: 1571 LESAMRKHLPDLFEEQPDLLHNLVTQFSPSLLKSEGVQAYRCVQREGEFVLTFPRAYHAG 1750 LE M+K P+LF+ QPDLLH LVT +P+ L S GV R Q GEFV+TFPRAYH+G Sbjct: 545 LEEVMKKLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEFVITFPRAYHSG 604 Query: 1751 FNCGFNCAEAVNVAPIDWLPVGQNAVELYREQARKITVSHDKLLLGAAREAIRAQWDILF 1930 FN G+N AEAVN DWLP G+ +E YR R SH++L+ A A + D+ Sbjct: 605 FNQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRYCVFSHEELICKMA--ACPEKLDL-- 660 Query: 1931 LKRNTADNLRWKSVCGPDSTICKSLKARIETELAQRQNLCSPSQSRKMDAEFD---SADR 2101 N A + + K + ++ E R+ L + F+ +R Sbjct: 661 ---NLA------------AAVHKEMFIMVQEERRLRKALLEKGITEAEREAFELLPDDER 705 Query: 2102 ECAFCYYDLHLSASGCPCCPEKYACLLHAKQLCSCDWDKRFFLFRYDVNELNILADALGG 2281 +C C LSA C CP+ CL H LC C +++ +RY ++EL + L Sbjct: 706 QCIKCKTTCFLSALACYDCPDGLVCLSHINDLCKCSSSRQYLRYRYTLDELPAMLHKLKV 765 Query: 2282 KLSAVHRW 2305 + + W Sbjct: 766 RAESFDTW 773 Score = 66.6 bits (161), Expect = 9e-10 Identities = 32/74 (43%), Positives = 47/74 (63%) Frame = +2 Query: 791 EAPVFHPTEEEFKDTLKYIESIRPTAEPYGICRIVPPPSWKPPCLLKEKSTWENSTFSTR 970 E PVF P+ EF+D L YI IRP AE GIC+I PP W+PP ++ +N F+ R Sbjct: 13 ECPVFEPSWAEFRDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEV----DNFRFTPR 68 Query: 971 VQKVDKLQNRTSSK 1012 +Q++++L+ +T K Sbjct: 69 IQRLNELEAQTRVK 82
>Q38JA7:JAD1C_CANFA Histone demethylase JARID1C - Canis familiaris (Dog)| Length = 1556 Score = 310 bits (794), Expect = 3e-83 Identities = 176/428 (41%), Positives = 235/428 (54%), Gaps = 10/428 (2%) Frame = +2 Query: 1052 LSEPEENSKRFGFEPGP-ELTLQKFQKYADYFSEQYFKKDASMNSLPSVEDIEGEYWRIV 1228 ++E + + FGFE E TLQ F + AD F YF M +P+ E +E E+WR+V Sbjct: 373 MAECKRPPEAFGFEQATREYTLQSFGEMADSFKADYFNMPVHM--VPT-ELVEKEFWRLV 429 Query: 1229 ESPTEEIEVIYGADLETGSFGSGFP------KLPPETKSDIEDKYAHSGWNLNNLPRLQG 1390 S E++ V YGAD+ + FGSGFP L PE E++YA SGWNLN +P L+ Sbjct: 430 NSIEEDVTVEYGADIHSKEFGSGFPVSDNKRHLTPE-----EEEYATSGWNLNVMPVLEQ 484 Query: 1391 SVLSFEGGDISGVLVPWVYVGMCFSSFCWHVEDHHLYSLNYLHWGAPKMWYGVPGKDAVN 1570 SVL DISG+ VPW+YVGM FS+FCWH+EDH YS+NYLHWG PK WYGVP A + Sbjct: 485 SVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSLAAEH 544 Query: 1571 LESAMRKHLPDLFEEQPDLLHNLVTQFSPSLLKSEGVQAYRCVQREGEFVLTFPRAYHAG 1750 LE M+K P+LF+ QPDLLH LVT +P+ L S GV R Q GEFV+TFPRAYH+G Sbjct: 545 LEEVMKKLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEFVITFPRAYHSG 604 Query: 1751 FNCGFNCAEAVNVAPIDWLPVGQNAVELYREQARKITVSHDKLLLGAAREAIRAQWDILF 1930 FN G+N AEAVN DWLP G+ +E YR R SH++L+ A A + D+ Sbjct: 605 FNQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRYCVFSHEELICKMA--ACPEKLDL-- 660 Query: 1931 LKRNTADNLRWKSVCGPDSTICKSLKARIETELAQRQNLCSPSQSRKMDAEFD---SADR 2101 N A + + K + ++ E R+ L + F+ +R Sbjct: 661 ---NLA------------AAVHKEMFIMVQEERRLRKALLEKGITEAEREAFELLPDDER 705 Query: 2102 ECAFCYYDLHLSASGCPCCPEKYACLLHAKQLCSCDWDKRFFLFRYDVNELNILADALGG 2281 +C C LSA C CP+ CL H LC C +++ +RY ++EL + L Sbjct: 706 QCIKCKTTCFLSALACYDCPDGLVCLSHINDLCKCSSSRQYLRYRYTLDELPAMLHKLKV 765 Query: 2282 KLSAVHRW 2305 + + W Sbjct: 766 RAESFDTW 773 Score = 66.6 bits (161), Expect = 9e-10 Identities = 32/74 (43%), Positives = 47/74 (63%) Frame = +2 Query: 791 EAPVFHPTEEEFKDTLKYIESIRPTAEPYGICRIVPPPSWKPPCLLKEKSTWENSTFSTR 970 E PVF P+ EF+D L YI IRP AE GIC+I PP W+PP ++ +N F+ R Sbjct: 13 ECPVFEPSWAEFRDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEV----DNFRFTPR 68 Query: 971 VQKVDKLQNRTSSK 1012 +Q++++L+ +T K Sbjct: 69 IQRLNELEAQTRVK 82
>Q62240:JAD1D_MOUSE Histone demethylase JARID1D - Mus musculus (Mouse)| Length = 1548 Score = 309 bits (792), Expect = 6e-83 Identities = 176/428 (41%), Positives = 233/428 (54%), Gaps = 10/428 (2%) Frame = +2 Query: 1052 LSEPEENSKRFGFEPGP-ELTLQKFQKYADYFSEQYFKKDASMNSLPSVEDIEGEYWRIV 1228 L+E + + FGFE E TLQ F + AD F YF M +P+ E +E E+WR+V Sbjct: 372 LAECKSPPEAFGFEQATQEYTLQSFGEMADSFKADYFNMPVHM--VPT-EVVEKEFWRLV 428 Query: 1229 ESPTEEIEVIYGADLETGSFGSGFP------KLPPETKSDIEDKYAHSGWNLNNLPRLQG 1390 S E++ V YGAD+ + FGSGFP L PE K +YA GWNLN +P L Sbjct: 429 SSIEEDVTVEYGADIHSKEFGSGFPVNNSKWDLSPEEK-----EYAACGWNLNVMPVLDQ 483 Query: 1391 SVLSFEGGDISGVLVPWVYVGMCFSSFCWHVEDHHLYSLNYLHWGAPKMWYGVPGKDAVN 1570 SVL DISG+ VPW+YVGM FS+FCWH+EDH YS+NYLHWG PK WYGVP A + Sbjct: 484 SVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSLAAEH 543 Query: 1571 LESAMRKHLPDLFEEQPDLLHNLVTQFSPSLLKSEGVQAYRCVQREGEFVLTFPRAYHAG 1750 LE M++ P+LF+ QPDLLH LVT +P+ L S GV R Q GEFV+TFPRAYH+G Sbjct: 544 LEDVMKRLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEFVITFPRAYHSG 603 Query: 1751 FNCGFNCAEAVNVAPIDWLPVGQNAVELYREQARKITVSHDKLLLGAAREAIRAQWDILF 1930 FN G+N AEAVN DWLPVG+ +E YR R SH++L+ A A + D+ Sbjct: 604 FNQGYNFAEAVNFCTADWLPVGRQCIEHYRRLRRYCVFSHEELICKMA--AFPEKLDL-- 659 Query: 1931 LKRNTADNLRWKSVCGPDSTICKSLKARIETELAQRQNLCSPSQSRKMDAEFD---SADR 2101 N A + K + ++ E R+ L + F+ +R Sbjct: 660 ---NLA------------VAVHKEMFIMVQEERRLRKTLLEKGITEAEREAFELLPDDER 704 Query: 2102 ECAFCYYDLHLSASGCPCCPEKYACLLHAKQLCSCDWDKRFFLFRYDVNELNILADALGG 2281 +C C LSA C CP+ CL H LC C ++++ +RY ++EL + L Sbjct: 705 QCIKCKTTCFLSALACYDCPDSLVCLSHINDLCKCSRNRQYLRYRYTLDELPAMLQKLKI 764 Query: 2282 KLSAVHRW 2305 + + W Sbjct: 765 RAESFDNW 772 Score = 66.6 bits (161), Expect = 9e-10 Identities = 32/74 (43%), Positives = 47/74 (63%) Frame = +2 Query: 791 EAPVFHPTEEEFKDTLKYIESIRPTAEPYGICRIVPPPSWKPPCLLKEKSTWENSTFSTR 970 E PVF P+ EF+D L YI IRP AE GIC+I PP W+PP ++ +N F+ R Sbjct: 13 ECPVFEPSWAEFRDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEV----DNFRFTPR 68 Query: 971 VQKVDKLQNRTSSK 1012 +Q++++L+ +T K Sbjct: 69 IQRLNELEAQTRVK 82
>A1YVX4:JAD1C_PIG Histone demethylase JARID1C - Sus scrofa (Pig)| Length = 1516 Score = 307 bits (786), Expect = 3e-82 Identities = 175/428 (40%), Positives = 234/428 (54%), Gaps = 10/428 (2%) Frame = +2 Query: 1052 LSEPEENSKRFGFEPGP-ELTLQKFQKYADYFSEQYFKKDASMNSLPSVEDIEGEYWRIV 1228 ++E + + FGFE E TLQ F + AD F Y M +P+ E +E E+WR+V Sbjct: 332 MAECKRPPEAFGFEQATREYTLQSFGEMADSFKADYSNMPVHM--VPT-ELVEKEFWRLV 388 Query: 1229 ESPTEEIEVIYGADLETGSFGSGFP------KLPPETKSDIEDKYAHSGWNLNNLPRLQG 1390 S E++ V YGAD+ + FGSGFP L PE E++YA SGWNLN +P L+ Sbjct: 389 NSIEEDVTVEYGADIHSKEFGSGFPVSDSKRHLTPE-----EEEYATSGWNLNVMPVLEQ 443 Query: 1391 SVLSFEGGDISGVLVPWVYVGMCFSSFCWHVEDHHLYSLNYLHWGAPKMWYGVPGKDAVN 1570 SVL DISG+ VPW+YVGM FS+FCWH+EDH YS+NYLHWG PK WYGVP A + Sbjct: 444 SVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSLAAEH 503 Query: 1571 LESAMRKHLPDLFEEQPDLLHNLVTQFSPSLLKSEGVQAYRCVQREGEFVLTFPRAYHAG 1750 LE M+K P+LF+ QPDLLH LVT +P+ L S GV R Q GEFV+TFPRAYH+G Sbjct: 504 LEEVMKKLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEFVITFPRAYHSG 563 Query: 1751 FNCGFNCAEAVNVAPIDWLPVGQNAVELYREQARKITVSHDKLLLGAAREAIRAQWDILF 1930 FN G+N AEAVN DWLP G+ +E YR R SH++L+ A A + D+ Sbjct: 564 FNQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRYCVFSHEELICKMA--ACPEKLDL-- 619 Query: 1931 LKRNTADNLRWKSVCGPDSTICKSLKARIETELAQRQNLCSPSQSRKMDAEFD---SADR 2101 N A + + K + ++ E R+ L + F+ +R Sbjct: 620 ---NLA------------AAVHKEMFIMVQEERRLRKALLEKGITEAEREAFELLPDDER 664 Query: 2102 ECAFCYYDLHLSASGCPCCPEKYACLLHAKQLCSCDWDKRFFLFRYDVNELNILADALGG 2281 +C C LSA C CP+ CL H LC C +++ +RY ++EL + L Sbjct: 665 QCIKCKTTCFLSALACYDCPDGLVCLSHINDLCKCSSSRQYLRYRYTLDELPAMLHKLKV 724 Query: 2282 KLSAVHRW 2305 + + W Sbjct: 725 RAESFDTW 732 Score = 64.3 bits (155), Expect = 4e-09 Identities = 30/68 (44%), Positives = 44/68 (64%) Frame = +2 Query: 791 EAPVFHPTEEEFKDTLKYIESIRPTAEPYGICRIVPPPSWKPPCLLKEKSTWENSTFSTR 970 E PVF P+ EF+D L YI IRP AE GIC+I PP W+PP ++ +N F+ R Sbjct: 13 ECPVFEPSWAEFRDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEV----DNFRFTPR 68 Query: 971 VQKVDKLQ 994 +Q++++L+ Sbjct: 69 IQRLNELE 76
>Q9BY66:JAD1D_HUMAN Histone demethylase JARID1D - Homo sapiens (Human)| Length = 1539 Score = 306 bits (785), Expect = 4e-82 Identities = 173/420 (41%), Positives = 230/420 (54%), Gaps = 2/420 (0%) Frame = +2 Query: 1052 LSEPEENSKRFGFEPGP-ELTLQKFQKYADYFSEQYFKKDASMNSLPSVEDIEGEYWRIV 1228 L+E ++ + FGFE E +LQ F + AD F YF M +P+ E +E E+WR+V Sbjct: 363 LAECKQPPEAFGFEQATQEYSLQSFGEMADSFKSDYFNMPVHM--VPT-ELVEKEFWRLV 419 Query: 1229 ESPTEEIEVIYGADLETGSFGSGFPKLPPETKSDIEDK-YAHSGWNLNNLPRLQGSVLSF 1405 S E++ V YGAD+ + FGSGFP + E+K YA SGWNLN +P L SVL Sbjct: 420 SSIEEDVTVEYGADIHSKEFGSGFPVSNSKQNLSPEEKEYATSGWNLNVMPVLDQSVLCH 479 Query: 1406 EGGDISGVLVPWVYVGMCFSSFCWHVEDHHLYSLNYLHWGAPKMWYGVPGKDAVNLESAM 1585 DISG+ VPW+YVGM FS+FCWH+EDH YS+NYLHWG PK WYGVP A +LE M Sbjct: 480 INADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSLAAEHLEEVM 539 Query: 1586 RKHLPDLFEEQPDLLHNLVTQFSPSLLKSEGVQAYRCVQREGEFVLTFPRAYHAGFNCGF 1765 + P+LF+ QPDLLH LVT +P+ L S GV R Q GEFV+TFPRAYH+GFN G+ Sbjct: 540 KMLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEFVITFPRAYHSGFNQGY 599 Query: 1766 NCAEAVNVAPIDWLPVGQNAVELYREQARKITVSHDKLLLGAAREAIRAQWDILFLKRNT 1945 N AEAVN DWLP G+ +E YR R SH++L+ A A + L L Sbjct: 600 NFAEAVNFCTADWLPAGRQCIEHYRRLRRYCVFSHEELICKMA-----AFPETLDLNLAV 654 Query: 1946 ADNLRWKSVCGPDSTICKSLKARIETELAQRQNLCSPSQSRKMDAEFDSADRECAFCYYD 2125 A + + + + K+L + TE + P +R+C C Sbjct: 655 AVHKEMFIMVQEERRLRKALLEKGVTEAEREAFELLPDD-----------ERQCIKCKTT 703 Query: 2126 LHLSASGCPCCPEKYACLLHAKQLCSCDWDKRFFLFRYDVNELNILADALGGKLSAVHRW 2305 LSA C CP+ CL H LC C +++ +RY ++EL + L + + W Sbjct: 704 CFLSALACYDCPDGLVCLSHINDLCKCSSSRQYLRYRYTLDELPTMLHKLKIRAESFDTW 763 Score = 66.6 bits (161), Expect = 9e-10 Identities = 33/74 (44%), Positives = 47/74 (63%) Frame = +2 Query: 791 EAPVFHPTEEEFKDTLKYIESIRPTAEPYGICRIVPPPSWKPPCLLKEKSTWENSTFSTR 970 E PVF P+ EF+D L YI IRP AE GIC+I PP W+PP ++ +N F+ R Sbjct: 13 ECPVFEPSWAEFQDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEV----DNFRFTPR 68 Query: 971 VQKVDKLQNRTSSK 1012 VQ++++L+ +T K Sbjct: 69 VQRLNELEAQTRVK 82
>Q30DN6:JAD1D_CANFA Histone demethylase JARID1D - Canis familiaris (Dog)| Length = 1545 Score = 306 bits (785), Expect = 4e-82 Identities = 173/423 (40%), Positives = 231/423 (54%), Gaps = 5/423 (1%) Frame = +2 Query: 1052 LSEPEENSKRFGFEPGP-ELTLQKFQKYADYFSEQYFKKDASMNSLPSVEDIEGEYWRIV 1228 ++E + + FGFE E TLQ F + AD F YF M +P+ E +E E+WR+V Sbjct: 366 MAECKRPPEAFGFEQATQEYTLQSFGEMADSFKADYFSMPVHM--VPT-ELVEKEFWRLV 422 Query: 1229 ESPTEEIEVIYGADLETGSFGSGFPKLPPET-KSDIEDKYAHSGWNLNNLPRLQGSVLSF 1405 S E++ V YGAD+ + FGSGFP + S E++YA SGWNLN +P L SVL Sbjct: 423 SSIEEDVTVEYGADIHSKEFGSGFPVSSSQRILSPEEEEYATSGWNLNVMPVLDQSVLCH 482 Query: 1406 EGGDISGVLVPWVYVGMCFSSFCWHVEDHHLYSLNYLHWGAPKMWYGVPGKDAVNLESAM 1585 DISG+ VPW+YVGM FS+FCWH+EDH YS+NYLHWG PK WYGVP A LE M Sbjct: 483 INADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSLAAEQLEEVM 542 Query: 1586 RKHLPDLFEEQPDLLHNLVTQFSPSLLKSEGVQAYRCVQREGEFVLTFPRAYHAGFNCGF 1765 ++ P+LF+ QPDLLH LVT +P+ L S GV R Q GEFV+TFPRAYH+GFN G+ Sbjct: 543 KRLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEFVITFPRAYHSGFNQGY 602 Query: 1766 NCAEAVNVAPIDWLPVGQNAVELYREQARKITVSHDKLLLGAAREAIRAQWDILFLKRNT 1945 N AEAVN DWLP G+ +E YR R SH++L+ A A + D+ N Sbjct: 603 NFAEAVNFCTADWLPAGRQCIEHYRRLRRYCVFSHEELICKMA--AFPEKLDL-----NL 655 Query: 1946 ADNLRWKSVCGPDSTICKSLKARIETELAQRQNLCSPSQSRKMDAEFD---SADRECAFC 2116 A + K + ++ E R+ L + F+ +R+C C Sbjct: 656 A------------VAVHKEMFIMVQEERRLRKALLEKGITEAEREAFELLPDDERQCIKC 703 Query: 2117 YYDLHLSASGCPCCPEKYACLLHAKQLCSCDWDKRFFLFRYDVNELNILADALGGKLSAV 2296 LSA C CP+ CL H LC C +++ +RY ++EL + L + + Sbjct: 704 KTTCFLSALACYDCPDGLVCLSHINDLCKCSSSRQYLRYRYTLDELPAMLHKLKIRAESF 763 Query: 2297 HRW 2305 W Sbjct: 764 DTW 766 Score = 68.6 bits (166), Expect = 2e-10 Identities = 33/74 (44%), Positives = 47/74 (63%) Frame = +2 Query: 791 EAPVFHPTEEEFKDTLKYIESIRPTAEPYGICRIVPPPSWKPPCLLKEKSTWENSTFSTR 970 E PVF PT EF+D L YI IRP AE GIC+I PP W+PP ++ +N F+ R Sbjct: 13 ECPVFEPTWAEFRDPLDYITKIRPIAEKSGICKIRPPADWQPPFAVEV----DNFRFTPR 68 Query: 971 VQKVDKLQNRTSSK 1012 +Q++++L+ +T K Sbjct: 69 IQRLNELEAQTRVK 82
>Q5XUN4:JAD1D_PANTR Histone demethylase JARID1D - Pan troglodytes (Chimpanzee)| Length = 1535 Score = 306 bits (784), Expect = 5e-82 Identities = 174/420 (41%), Positives = 229/420 (54%), Gaps = 2/420 (0%) Frame = +2 Query: 1052 LSEPEENSKRFGFEPGP-ELTLQKFQKYADYFSEQYFKKDASMNSLPSVEDIEGEYWRIV 1228 L+E ++ + FGFE E TLQ F + AD F YF M +P+ E +E E+WR+V Sbjct: 363 LAECKQPPEAFGFEQATQEYTLQSFGEMADSFKSDYFNMPVHM--VPT-ELLEKEFWRLV 419 Query: 1229 ESPTEEIEVIYGADLETGSFGSGFPKLPPETKSDIEDK-YAHSGWNLNNLPRLQGSVLSF 1405 S E++ V YGAD+ FGSGFP + E+K YA SGWNLN +P L SVL Sbjct: 420 SSIEEDVTVEYGADIHYKEFGSGFPVSNSKQNLSPEEKEYATSGWNLNVMPVLAQSVLCH 479 Query: 1406 EGGDISGVLVPWVYVGMCFSSFCWHVEDHHLYSLNYLHWGAPKMWYGVPGKDAVNLESAM 1585 DISG+ VPW+YVGM FS+FCWH+EDH YS+NYLHWG PK WYGVP A +LE M Sbjct: 480 INADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSLAAEHLEEVM 539 Query: 1586 RKHLPDLFEEQPDLLHNLVTQFSPSLLKSEGVQAYRCVQREGEFVLTFPRAYHAGFNCGF 1765 + P+LF+ QPDLLH LVT +P+ L S GV R Q GEFV+TFPRAYH+GFN G+ Sbjct: 540 KMLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEFVITFPRAYHSGFNQGY 599 Query: 1766 NCAEAVNVAPIDWLPVGQNAVELYREQARKITVSHDKLLLGAAREAIRAQWDILFLKRNT 1945 N AEAVN DWLP G+ +E YR R SH++L+ A A + L L Sbjct: 600 NFAEAVNFCTADWLPAGRQCIEHYRRLRRYCVFSHEELICKMA-----AFPETLDLNLAV 654 Query: 1946 ADNLRWKSVCGPDSTICKSLKARIETELAQRQNLCSPSQSRKMDAEFDSADRECAFCYYD 2125 A + + + + K+L + TE + P +R+C C Sbjct: 655 AVHKEMFIMVQEERRLRKALLEKGVTEAEREAFELLPDD-----------ERQCIKCKTT 703 Query: 2126 LHLSASGCPCCPEKYACLLHAKQLCSCDWDKRFFLFRYDVNELNILADALGGKLSAVHRW 2305 LSA C CP+ CL H LC C +++ +RY ++EL + L + + W Sbjct: 704 CFLSALACYDCPDGLVCLSHINDLCKCSSSRQYLRYRYTLDELPTMLHKLKIRAESFDTW 763 Score = 66.2 bits (160), Expect = 1e-09 Identities = 32/74 (43%), Positives = 47/74 (63%) Frame = +2 Query: 791 EAPVFHPTEEEFKDTLKYIESIRPTAEPYGICRIVPPPSWKPPCLLKEKSTWENSTFSTR 970 E PVF P+ EF+D L YI IRP AE GIC+I PP W+PP ++ +N F+ R Sbjct: 13 ECPVFEPSWAEFQDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEV----DNFRFTPR 68 Query: 971 VQKVDKLQNRTSSK 1012 +Q++++L+ +T K Sbjct: 69 IQRLNELEAQTRVK 82
>Q6IQX0:JAD1B_DANRE Histone demethylase JARID1B - Danio rerio (Zebrafish) (Brachydanio| rerio) Length = 1503 Score = 305 bits (782), Expect = 8e-82 Identities = 166/418 (39%), Positives = 234/418 (55%), Gaps = 10/418 (2%) Frame = +2 Query: 1082 FGFEPGP-ELTLQKFQKYADYFSEQYFKKDASMNSLPSVEDIEGEYWRIVESPTEEIEVI 1258 FGFE + TL+ F + AD F YF M +P+ E +E E+WR+V + E++ V Sbjct: 354 FGFEQAHRDYTLKAFGEMADSFKSDYFNMPVHM--VPT-ELVEKEFWRLVGTIQEDVTVE 410 Query: 1259 YGADLETGSFGSGFP------KLPPETKSDIEDKYAHSGWNLNNLPRLQGSVLSFEGGDI 1420 YGAD+ + FGSGFP K+ P ++KY GWNLNN+ + SVL+ DI Sbjct: 411 YGADIASKEFGSGFPIKGGRFKIAPH-----DEKYLQCGWNLNNMAMMTPSVLTHVTADI 465 Query: 1421 SGVLVPWVYVGMCFSSFCWHVEDHHLYSLNYLHWGAPKMWYGVPGKDAVNLESAMRKHLP 1600 G+ +PW+YVGMCFSSFCWH+EDH YS+NYLHWG PK WYG PG A LE+ M+K P Sbjct: 466 CGMTLPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGAPGFAAEQLEAVMKKLAP 525 Query: 1601 DLFEEQPDLLHNLVTQFSPSLLKSEGVQAYRCVQREGEFVLTFPRAYHAGFNCGFNCAEA 1780 +LF+ QPDLLH LVT +P+ L + GV YR Q GEFV+TFPR+YH+GFN GFN AEA Sbjct: 526 ELFDSQPDLLHQLVTIMNPNTLMAHGVPIYRTNQCAGEFVITFPRSYHSGFNQGFNFAEA 585 Query: 1781 VNVAPIDWLPVGQNAVELYREQARKITVSHDKLLLGAAREAIRAQWDILFLKRNTADNLR 1960 VN +DW+P+G+ V+ YR+ R SHD+++ A +A D++ Sbjct: 586 VNFCTVDWMPLGRQCVDHYRQLHRYCVFSHDEMVCNMAMKA--DCLDVVLA--------- 634 Query: 1961 WKSVCGPDSTICKSLKARIETELAQRQNLCSPSQSRKMDAEFD---SADRECAFCYYDLH 2131 S + K ++ I+ E R+ + ++ ++D +R+C C + Sbjct: 635 --------SAVQKDMQLMIKEERELREKVRKMGVAQCELFQYDLLADDERQCVKCRTTCY 686 Query: 2132 LSASGCPCCPEKYACLLHAKQLCSCDWDKRFFLFRYDVNELNILADALGGKLSAVHRW 2305 LSA CPC P CL H LCSC +R+ +++L + +A+ + W Sbjct: 687 LSALTCPCRPGVQVCLYHTHDLCSCPISNYTLNYRFTLDDLYPMMNAVRQRAEYYDDW 744 Score = 66.2 bits (160), Expect = 1e-09 Identities = 31/74 (41%), Positives = 45/74 (60%) Frame = +2 Query: 791 EAPVFHPTEEEFKDTLKYIESIRPTAEPYGICRIVPPPSWKPPCLLKEKSTWENSTFSTR 970 E PVF P+ EEFKD +I IRP AE GIC++ PPP W+PP + F+ R Sbjct: 14 ECPVFEPSWEEFKDPFAFINKIRPIAEKTGICKVRPPPDWQPPFACDV----DRLHFTPR 69 Query: 971 VQKVDKLQNRTSSK 1012 +Q++++L+ +T K Sbjct: 70 IQRLNELEAQTRVK 83
>Q23541:JAD1_CAEEL Histone demethylase rbr-2 - Caenorhabditis elegans| Length = 1477 Score = 270 bits (691), Expect = 3e-71 Identities = 171/456 (37%), Positives = 239/456 (52%), Gaps = 8/456 (1%) Frame = +2 Query: 1088 FEPGPELTLQKFQKYADYFSEQYFK-KDASMNSLPSVEDIEGEYWRIVESPTEEIEVIYG 1264 ++ E L F ++A+ + YF KD S S +VE +W+ V S + V YG Sbjct: 383 YDADTEYNLNSFTEFANKWKCDYFGVKDVSQVSCDAVER---SFWKNVISHENPVSVKYG 439 Query: 1265 ADLETGSFGSGFPKLP-----PETKSDIEDKYAHSGWNLNNLPRLQGSVLSFEGGDISGV 1429 ADL T GSGFP+ P+ K ++ +YA WNLNN+P L+ SVLS ISG+ Sbjct: 440 ADLITSRVGSGFPRKEDKHTGPDLK--LKQQYASHAWNLNNMPVLRESVLSHFNTGISGM 497 Query: 1430 LVPWVYVGMCFSSFCWHVEDHHLYSLNYLHWGAPKMWYGVPGKDAVNLESAMRKHLPDLF 1609 +VPWVYVGMCFS+FCWH EDH YS+NY H+G K+WYGV G+DA E A++K P L Sbjct: 498 MVPWVYVGMCFSTFCWHTEDHWTYSVNYNHFGERKIWYGVGGEDAEKFEDALKKIAPGLT 557 Query: 1610 EEQPDLLHNLVTQFSPSLLKSEGVQAYRCVQREGEFVLTFPRAYHAGFNCGFNCAEAVNV 1789 Q DL H++ T +P LL+S GV + Q GEFV+TFPRAYHAGFN G N AEAVN Sbjct: 558 GRQRDLFHHMTTAANPHLLRSLGVPIHSVHQNAGEFVITFPRAYHAGFNEGLNFAEAVNF 617 Query: 1790 APIDWLPVGQNAVELYREQARKITVSHDKLLLGAAREAIRAQWDILFLKRNTADNLRWKS 1969 APIDWL G+ VE Y R + SHD+LL EA+ D L + + A + Sbjct: 618 APIDWLSKGRECVESYSNVRRYLVFSHDELLFKMV-EAM----DKLGISMSLATH----- 667 Query: 1970 VCGPDSTICKSLKARIETELAQRQNLCSPSQSRKMDAEFDSADRECAFCYYDLHLSASGC 2149 + I K ++ EL R + + + M + R C FC L + A C Sbjct: 668 ----EELIRIYEKQKMLRELLARLGVSNRQMQQVMFEKIPDEQRSCRFCKTTLFMCALVC 723 Query: 2150 PCCPEKYACLLHAKQLC-SCDWDKRFFLFRYDVNELNILADALGGKLSAVHRW-GVSDLG 2323 +K C+ H LC SC + +R+++++LN + D LG + + W SD Sbjct: 724 N-KHKKMTCVEHHDHLCNSCTTKDYRYQYRFELDQLNNMCDELGKRTVNYNGWKEESDEM 782 Query: 2324 LSLSSCVKREKVQDSKTVRRSTDGPRRSYMSQASTV 2431 L K E++++ + P+ + + T+ Sbjct: 783 LEEEGKPKLERIEEFIDSAKQNKYPQTDQVHKLITI 818 Score = 63.5 bits (153), Expect = 7e-09 Identities = 28/67 (41%), Positives = 46/67 (68%) Frame = +2 Query: 794 APVFHPTEEEFKDTLKYIESIRPTAEPYGICRIVPPPSWKPPCLLKEKSTWENSTFSTRV 973 AP+++PTEEEF D ++Y+ IR AE +G+ +IVPP ++KPP + + E TF R Sbjct: 56 APIYYPTEEEFSDPIEYVAKIRHEAEKFGVVKIVPPANFKPPFAIDK----EAFTFRPRT 111 Query: 974 QKVDKLQ 994 QK+++++ Sbjct: 112 QKLNEVE 118
>Q61T02:JAD1_CAEBR Histone demethylase rbr-2 - Caenorhabditis briggsae| Length = 1436 Score = 265 bits (677), Expect = 1e-69 Identities = 164/421 (38%), Positives = 221/421 (52%), Gaps = 11/421 (2%) Frame = +2 Query: 1088 FEPGPELTLQKFQKYADYFSEQYFKKDASMNSLPSVEDIEGEYWRIVESPTEEIEVIYGA 1267 ++ E L F ++A+ + YF D S S + +E E+W+ V S + V YGA Sbjct: 340 YDAETEYNLNTFTEFANKWKCDYFGVDNV--SKVSCDALEKEFWKNVVSHDNPVAVKYGA 397 Query: 1268 DLETGSFGSGFPKLPPE---TKSDIEDKYAHSGWNLNNLPRLQGSVLSFEGGDISGVLVP 1438 DL T GSGFP+ + S ++ +YA+ WNLNN+P L SVLS+ ISG++VP Sbjct: 398 DLITSRVGSGFPRKEDKHTGPDSKLKQQYANHAWNLNNMPVLSESVLSYFNTGISGMMVP 457 Query: 1439 WVYVGMCFSSFCWHVEDHHLYSLNYLHWGAPKMWYGVPGKDAVNLESAMRKHLPDLFEEQ 1618 WVYVGMCFS+FCWH EDH YS+NY H+G K+WYGV G DA E A+++ P L Q Sbjct: 458 WVYVGMCFSTFCWHTEDHWTYSVNYNHFGERKIWYGVGGDDAEKFEEALKRLAPGLTGRQ 517 Query: 1619 PDLLHNLVTQFSPSLLKSEGVQAYRCVQREGEFVLTFPRAYHAGFNCGFNCAEAVNVAPI 1798 DL H++ T +PSLL+S GV Y Q GEFV+TFPRAYHAG+N G N AEAVN API Sbjct: 518 RDLFHHMTTAANPSLLRSLGVPIYSVHQNAGEFVITFPRAYHAGYNEGLNFAEAVNFAPI 577 Query: 1799 DWLPVGQNAVELYREQARKITVSHDKLLLGAAREAIRAQWDILFLKRNTADNLRWKSVCG 1978 DWL G+ V+ Y R + SHD+L LF D L G Sbjct: 578 DWLAKGRECVQSYSNVRRYLVFSHDEL---------------LFKMIEAMDRL------G 616 Query: 1979 PDSTIC--KSLKARIETELAQRQ---NLCSPSQSRKMDA--EFDSADRECAFCYYDLHLS 2137 +T+ LK IE + RQ L P+++ + A + R C FC L + Sbjct: 617 LSTTLAAYDELKRVIEKQKRLRQFIAQLGVPARNVEQVAFEKIPDEQRSCRFCKTTLFMC 676 Query: 2138 ASGCPCCPEKYACLLHAKQLCSCDWDKRF-FLFRYDVNELNILADALGGKLSAVHRWGVS 2314 A C ++ C+ H LC K + + +RY+++ L L D LG + W Sbjct: 677 ALICN-KHKRMTCVEHHDHLCKTCTPKDYKYQYRYEIDNLTHLFDELGKRTVDTAGWQED 735 Query: 2315 D 2317 D Sbjct: 736 D 736 Score = 66.6 bits (161), Expect = 9e-10 Identities = 30/67 (44%), Positives = 45/67 (67%) Frame = +2 Query: 794 APVFHPTEEEFKDTLKYIESIRPTAEPYGICRIVPPPSWKPPCLLKEKSTWENSTFSTRV 973 APV++PT EEF D ++Y+ IRP AE YG+ +IVPP +KPP + + E TF R Sbjct: 61 APVYYPTSEEFADPIEYVAKIRPDAERYGVVKIVPPSDFKPPFAIDK----EKFTFRPRT 116 Query: 974 QKVDKLQ 994 QK+++++ Sbjct: 117 QKLNEVE 123
>Q9US53:JMJ2_SCHPO Jumonji/ARID domain-containing protein 2 - Schizosaccharomyces pombe| (Fission yeast) Length = 715 Score = 249 bits (636), Expect = 7e-65 Identities = 150/416 (36%), Positives = 201/416 (48%), Gaps = 18/416 (4%) Frame = +2 Query: 1070 NSKRFGFEPGPELTLQKFQKYADYFSEQYFKKDASMNSLPSVEDIEGEYWRIVESPTEEI 1249 N FGFE G TL F+KY D F + YF K + +E EYW++V+ + Sbjct: 338 NPYEFGFETGNYYTLSNFEKYCDNFKKNYFSKFKDSEITEDI--VEKEYWKLVKDNNTSL 395 Query: 1250 EVIYGADLETGSFGSGFPKLPPETKSDIEDKYAHSGWNLNNLPRLQGSVLSFEGGDISGV 1429 EV YGADL T GS FP L K+ + + Y+ WNLN + GS+LS+ +SG+ Sbjct: 396 EVEYGADLSTLDQGSAFPSL---AKNPV-NPYSKDTWNLNVIASTNGSLLSYIDNPVSGI 451 Query: 1430 LVPWVYVGMCFSSFCWHVEDHHLYSLNYLHWGAPKMWYGVPGKDAVNLESAMRKHLPDLF 1609 PW+YVGMCFS+FCWHVED++ YS+NY H+G K+WYG+PG A E A PDL Sbjct: 452 TCPWLYVGMCFSTFCWHVEDNYTYSVNYQHYGDTKLWYGIPGDQAERFERAALDIAPDLV 511 Query: 1610 EEQPDLLHNLVTQFSPSLLKSEGVQAYRCVQREGEFVLTFPRAYHAGFNCGFNCAEAVNV 1789 ++Q DLL+ L T +P L+ GV Y Q EFV+TFP+++HAG N GFN EAVN Sbjct: 512 KKQKDLLYQLATMINPDELQKRGVDVYFIDQGPNEFVITFPKSFHAGINHGFNINEAVNF 571 Query: 1790 APIDWLPVG--QNAVELYREQARKITVSHDKLLLGAA----------------REAIRAQ 1915 AP DWL G N V Y+ + +SHD L+ A EA++ + Sbjct: 572 APKDWLLNGFSLNGVLKYQSLLKPPVLSHDMLVYNLATNPASEISVSELRPWVHEAVKRE 631 Query: 1916 WDILFLKRNTADNLRWKSVCGPDSTICKSLKARIETELAQRQNLCSPSQSRKMDAEFDSA 2095 I + R D LK + EL + D+ Sbjct: 632 LGIRIMIRGRYD-----------------LKEILYRELME-----------------DAE 657 Query: 2096 DRECAFCYYDLHLSASGCPCCPEKYACLLHAKQLCSCDWDKRFFLFRYDVNELNIL 2263 + +C C + S C C C LH + LC CD + + D NEL L Sbjct: 658 NWQCQHCKAFSYFSQVAC-SCKSITVCPLHIEYLCKCDLSNKTLRLKVDDNELQKL 712 Score = 61.2 bits (147), Expect = 4e-08 Identities = 30/67 (44%), Positives = 40/67 (59%) Frame = +2 Query: 785 LDEAPVFHPTEEEFKDTLKYIESIRPTAEPYGICRIVPPPSWKPPCLLKEKSTWENSTFS 964 L APVF+P +EEF+D++ YI I P E YGI +IVPP W PP L + + FS Sbjct: 57 LPVAPVFYPDKEEFQDSIGYINKIAPIGEKYGIIKIVPPAGWNPPMQL------DMNKFS 110 Query: 965 TRVQKVD 985 R ++ D Sbjct: 111 FRTRRQD 117
>P47156:JAD1_YEAST Histone demethylase YJR119C - Saccharomyces cerevisiae (Baker's| yeast) Length = 728 Score = 174 bits (440), Expect = 4e-42 Identities = 99/262 (37%), Positives = 137/262 (52%), Gaps = 16/262 (6%) Frame = +2 Query: 1103 ELTLQKFQKYADYFSEQYFKKDASMNSLP----SVEDIEGEYWRIVESPTEE--IEVIYG 1264 + +L +FQ+Y K + LP S++++E +W +V V YG Sbjct: 297 DYSLPEFQEYC---------KRQNSRLLPARKLSIDELEEMFWSLVTKNRRSSLTTVKYG 347 Query: 1265 ADLETGSFG--SGFPK---LPPETKSD-IED--KYAHSGWNLNNLPRLQGSVLSFEGGDI 1420 AD+ G +GFP +P D + D KY NL NLP S+L +I Sbjct: 348 ADIHNELPGQITGFPTREFIPKNINGDELIDYLKYCDHPMNLTNLPMAHNSLLPLFKRNI 407 Query: 1421 SGVLVPWVYVGMCFSSFCWHVEDHHLYSLNYLHWGAPKMWYGVPGKDAVNLESAMRKHLP 1600 SG+ +PW+Y+G FS+FCWH+ED + S NY H G PK+WY +P + P Sbjct: 408 SGMTIPWIYIGSLFSTFCWHMEDQYTLSANYQHEGDPKVWYSIPESGCTKFNDLLNDMSP 467 Query: 1601 DLFEEQPDLLHNLVTQFSP--SLLKSEGVQAYRCVQREGEFVLTFPRAYHAGFNCGFNCA 1774 DLF +QPDLLH LVT SP K G+ Y+ VQ+ E+++TFP+ YHAGFN G+N Sbjct: 468 DLFIKQPDLLHQLVTLISPYDPNFKKSGIPVYKAVQKPNEYIITFPKCYHAGFNTGYNFN 527 Query: 1775 EAVNVAPIDWLPVGQNAVELYR 1840 EAVN WLP G A+ Y+ Sbjct: 528 EAVNFTIDFWLPYGFGAITDYK 549 Score = 50.4 bits (119), Expect = 6e-05 Identities = 26/97 (26%), Positives = 50/97 (51%), Gaps = 2/97 (2%) Frame = +2 Query: 785 LDEAPVFHPTEEEFKDTLKYIES--IRPTAEPYGICRIVPPPSWKPPCLLKEKSTWENST 958 ++E P +PTE+EFK+ + Y+ + I+ YG+ ++VPP + PP + EN T Sbjct: 1 MEEIPALYPTEQEFKNPIDYLSNPHIKRLGVRYGMVKVVPPNGFCPPLSI----DMENFT 56 Query: 959 FSTRVQKVDKLQNRTSSKKSTRGGMMKKRRKLSEPEE 1069 F R+Q ++ L + + + +R + +P + Sbjct: 57 FQPRIQNLENLDLKNRCRLFFMKQLNNFKRSVKDPSK 93
>Q6B0I6:JHD3D_HUMAN JmjC domain-containing histone demethylation protein 3D - Homo| sapiens (Human) Length = 520 Score = 168 bits (425), Expect = 2e-40 Identities = 123/365 (33%), Positives = 166/365 (45%), Gaps = 7/365 (1%) Frame = +2 Query: 800 VFHPTEEEFKDTLKYIESIRPT-AEPYGICRIVPPPSWKPPCLLKEKSTWENSTFSTRVQ 976 +FHPT+EEF D KYI + A G+ +I+PP W K + T++N + + Sbjct: 17 IFHPTKEEFNDFDKYIAYMESQGAHRAGLAKIIPPKEW------KARETYDN---ISEIL 67 Query: 977 KVDKLQNRTSSKKSTRGGMMKKRRKLSEPE----ENSKRFGFEPGPELTLQKFQKYADYF 1144 LQ S + KK++ ++ E NSK++ P Q F Sbjct: 68 IATPLQQVASGRAGVFTQYHKKKKAMTVGEYRHLANSKKYQTPPH-----QNF------- 115 Query: 1145 SEQYFKKDASMNSLPSVEDIEGEYW--RIVESPTEEIEVIYGADLETGSFGSGFPKLPPE 1318 ED+E +YW RI SP IYGAD+ F Sbjct: 116 -----------------EDLERKYWKNRIYNSP------IYGADISGSLFDE-------N 145 Query: 1319 TKSDIEDKYAHSGWNLNNLPRLQGSVLSFEGGDISGVLVPWVYVGMCFSSFCWHVEDHHL 1498 TK WNL +L +Q + G I GV P++Y GM ++F WH ED L Sbjct: 146 TKQ----------WNLGHLGTIQDLLEKECGVVIEGVNTPYLYFGMWKTTFAWHTEDMDL 195 Query: 1499 YSLNYLHWGAPKMWYGVPGKDAVNLESAMRKHLPDLFEEQPDLLHNLVTQFSPSLLKSEG 1678 YS+NYLH G PK WY VP + LE R+ P L + V SP++LK G Sbjct: 196 YSINYLHLGEPKTWYVVPPEHGQRLERLARELFPGSSRGCGAFLRHKVALISPTVLKENG 255 Query: 1679 VQAYRCVQREGEFVLTFPRAYHAGFNCGFNCAEAVNVAPIDWLPVGQNAVELYREQARKI 1858 + R Q GEF++TFP YHAGFN GFNCAEA+N A W+ G+ A + +AR + Sbjct: 256 IPFNRITQEAGEFMVTFPYGYHAGFNHGFNCAEAINFATPRWIDYGKMASQCSCGEAR-V 314 Query: 1859 TVSHD 1873 T S D Sbjct: 315 TFSMD 319
>P39956:RPH1_YEAST DNA damage-responsive transcriptional repressor RPH1 - Saccharomyces| cerevisiae (Baker's yeast) Length = 796 Score = 166 bits (419), Expect = 1e-39 Identities = 108/373 (28%), Positives = 175/373 (46%), Gaps = 25/373 (6%) Frame = +2 Query: 782 VLDEAPVFHPTEEEFKDTLKYIESIRPTAEPYGICRIVPPPSWKPPCLL----------K 931 ++ PVF PT E+F+D Y ++I G+ +++PP WK L K Sbjct: 10 IVGGVPVFKPTYEQFEDFYAYCKAINKYGMKSGVVKVIPPKEWKDKLDLPYSAETLQKIK 69 Query: 932 EKSTWENSTFSTR----VQKVDK------LQNRTSSKKSTRGGMMKKRRKLSEPEENSKR 1081 KS + + VQ V+K +Q + SK K RR NS++ Sbjct: 70 IKSPIQQHISGNKGLFMVQNVEKNKTYNIIQWKDLSKDYVPPEDPKARR-------NSRK 122 Query: 1082 FGFEPGPELTLQKFQKYADYFSEQYFKKDASMN-----SLPSVEDIEGEYWRIVESPTEE 1246 +L L+ F+ + + F+ + +++ + ++ +E YW+ + T Sbjct: 123 GSVSKSTKLKLKNFESSFNIDDFEQFRTEYTIDLSDFQNTERLKFLEEYYWKTLNFTTP- 181 Query: 1247 IEVIYGADLETGSFGSGFPKLPPETKSDIEDKYAHSGWNLNNLPRLQGSVLSFEGGDISG 1426 +YGAD F G + WN+ LP ++L + G Sbjct: 182 ---MYGADTPGSIFPEGL-----------------NVWNVAKLP----NILDHMETKVPG 217 Query: 1427 VLVPWVYVGMCFSSFCWHVEDHHLYSLNYLHWGAPKMWYGVPGKDAVNLESAMRKHLPDL 1606 V ++Y G+ +SF WH+ED LYS+NY+H+GAPK WY +P +D M++ P+ Sbjct: 218 VNDSYLYAGLWKASFSWHLEDQDLYSINYIHFGAPKQWYSIPQEDRFKFYKFMQEQFPEE 277 Query: 1607 FEEQPDLLHNLVTQFSPSLLKSEGVQAYRCVQREGEFVLTFPRAYHAGFNCGFNCAEAVN 1786 + P+ L + + SP LL+ G++ V EGEF++T+P YHAGFN G+N AE+VN Sbjct: 278 AKNCPEFLRHKMFLASPKLLQENGIRCNEIVHHEGEFMITYPYGYHAGFNYGYNLAESVN 337 Query: 1787 VAPIDWLPVGQNA 1825 A +WLP+G+ A Sbjct: 338 FALEEWLPIGKKA 350
>Q3U2K5:JHD3D_MOUSE JmjC domain-containing histone demethylation protein 3D - Mus| musculus (Mouse) Length = 510 Score = 164 bits (414), Expect = 4e-39 Identities = 118/356 (33%), Positives = 170/356 (47%), Gaps = 5/356 (1%) Frame = +2 Query: 800 VFHPTEEEFKDTLKYIESIRPT-AEPYGICRIVPPPSWKPPCLLKEKSTWENSTFSTRVQ 976 +F PT+EEF D KYI + A G+ +++PP W+ + N +T +Q Sbjct: 17 IFRPTKEEFNDFDKYIAYMESQGAHRAGLAKVIPPKEWR---ARQSYDNISNILIATPLQ 73 Query: 977 KVDKLQNR--TSSKKSTRGGMMKKRRKLSEPEENSKRFGFEPGPELTLQKFQKYADYFSE 1150 +V Q T K +G + + R+L+ NSK++ P + D+ Sbjct: 74 QVVSGQAGVFTQYHKKKKGMTVGEYRELA----NSKKYQTPP-----------HLDF--- 115 Query: 1151 QYFKKDASMNSLPSVEDIEGEYW--RIVESPTEEIEVIYGADLETGSFGSGFPKLPPETK 1324 ED+E +YW R+ ESP IYGAD+ +GS G +T+ Sbjct: 116 ---------------EDLERKYWKNRLYESP------IYGADV-SGSLFDG------KTQ 147 Query: 1325 SDIEDKYAHSGWNLNNLPRLQGSVLSFEGGDISGVLVPWVYVGMCFSSFCWHVEDHHLYS 1504 WN+ +L +Q + G I GV P++Y GM ++F WH ED LYS Sbjct: 148 Q----------WNVGHLGTIQDLLEQECGIVIEGVNTPYLYFGMWKTTFAWHTEDMDLYS 197 Query: 1505 LNYLHWGAPKMWYGVPGKDAVNLESAMRKHLPDLFEEQPDLLHNLVTQFSPSLLKSEGVQ 1684 +NYLH+G PK WY VP + LE R+ P + L + V SP++LK G+ Sbjct: 198 INYLHFGQPKTWYAVPPEHGRRLERLARELFPGSSQGCQAFLRHKVALISPTVLKENGIP 257 Query: 1685 AYRCVQREGEFVLTFPRAYHAGFNCGFNCAEAVNVAPIDWLPVGQNAVELYREQAR 1852 R Q GEF++TFP YHAGFN GFNCAEA+N A W+ G+ A + +AR Sbjct: 258 FGRITQEAGEFMVTFPYGYHAGFNHGFNCAEAINFATPRWIDYGKVASQCSCGEAR 313
>O94953:JHD3B_HUMAN JmjC domain-containing histone demethylation protein 3B - Homo| sapiens (Human) Length = 1096 Score = 157 bits (396), Expect = 5e-37 Identities = 126/444 (28%), Positives = 199/444 (44%), Gaps = 4/444 (0%) Frame = +2 Query: 767 GARRPVLDEAPVFHPTEEEFKDTLKYIESIRPT-AEPYGICRIVPPPSWKPPCLLKEKST 943 GA+ P + F PT EEFKD KY+ I A G+ +I+PP WKP + Sbjct: 7 GAQNPSC-KIMTFRPTMEEFKDFNKYVAYIESQGAHRAGLAKIIPPKEWKPR---QTYDD 62 Query: 944 WENSTFSTRVQKVDKLQNRTSSKKSTRGGMMKKRRKLSEPEENSKRFGFEPGPELTLQKF 1123 ++ +Q+V Q S T+ + KK +T+ ++ Sbjct: 63 IDDVVIPAPIQQVVTGQ----SGLFTQYNIQKKA--------------------MTVGEY 98 Query: 1124 QKYADYFSEQYFKKDASMNSLPSVEDIEGEYWRIVESPTEEIEVIYGADLETGSFGSGFP 1303 ++ A+ SE+Y +D+E +YW+ + + IYGAD+ + Sbjct: 99 RRLAN--SEKYCTPRHQ-----DFDDLERKYWKNLTF----VSPIYGADISGSLY----- 142 Query: 1304 KLPPETKSDIEDKYAHSGWNLNNLPRLQGSVLSFEGGDISGVLVPWVYVGMCFSSFCWHV 1483 +D A WN+ +L + V G I GV P++Y GM ++F WH Sbjct: 143 ----------DDDVAQ--WNIGSLRTILDMVERECGTIIEGVNTPYLYFGMWKTTFAWHT 190 Query: 1484 EDHHLYSLNYLHWGAPKMWYGVPGKDAVNLESAMRKHLPDLFEEQPDLLHNLVTQFSPSL 1663 ED LYS+NYLH+G PK WY +P + LE P + L + +T SP + Sbjct: 191 EDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAIGFFPGSSQGCDAFLRHKMTLISPII 250 Query: 1664 LKSEGVQAYRCVQREGEFVLTFPRAYHAGFNCGFNCAEAVNVAPIDWLPVGQNAVE-LYR 1840 LK G+ R Q GEF++TFP YHAGFN GFNCAE+ N A + W+ G+ A + R Sbjct: 251 LKKYGIPFSRITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATLRWIDYGKVATQCTCR 310 Query: 1841 EQARKITVSHDKLLLGAAREAIRAQWDILFLKRNTADNLRWKSVCGPDSTICKSLKARIE 2020 + KI++ +L R + Q L D+ R ++ P+ + + +A ++ Sbjct: 311 KDMVKISMDVFVRILQPERYELWKQGKDL----TVLDHTRPTALTSPELSSWSASRASLK 366 Query: 2021 TELAQR--QNLCSPSQSRKMDAEF 2086 +L +R + P + + D +F Sbjct: 367 AKLLRRSHRKRSQPKKPKPEDPKF 390
>Q5RD88:JHD3A_PONPY JmjC domain-containing histone demethylation protein 3A - Pongo| pygmaeus (Orangutan) Length = 1064 Score = 157 bits (396), Expect = 5e-37 Identities = 117/399 (29%), Positives = 179/399 (44%), Gaps = 2/399 (0%) Frame = +2 Query: 803 FHPTEEEFKDTLKYIESIRPT-AEPYGICRIVPPPSWKPPCLLKEKSTWENSTFSTRVQK 979 F+PT EEF++ +YI I A G+ ++VPP WKP ++++++ Sbjct: 17 FYPTMEEFRNFSRYIAYIESQGAHRAGLAKVVPPKEWKP------RASYDDIDDLVIPAP 70 Query: 980 VDKLQNRTSSKKSTRGGMMKKRRKLSEPEENSKRFGFEPGPELTLQKFQKYADYFSEQYF 1159 + +L S T+ + KK +T+++F+K A+ S++Y Sbjct: 71 IQQLVTGQSGL-FTQYNIQKKA--------------------MTVREFRKIAN--SDKYC 107 Query: 1160 KKDASMNSLPSVEDIEGEYWR-IVESPTEEIEVIYGADLETGSFGSGFPKLPPETKSDIE 1336 S E++E +YW+ + +P IYGAD+ G+ + K E Sbjct: 108 TPRYS-----EFEELERKYWKNLTFNPP-----IYGADVN----GTLYEKHVDE------ 147 Query: 1337 DKYAHSGWNLNNLPRLQGSVLSFEGGDISGVLVPWVYVGMCFSSFCWHVEDHHLYSLNYL 1516 WN+ L + V G I GV P++Y GM +SF WH ED LYS+NYL Sbjct: 148 -------WNIGRLRTILDLVEKESGITIEGVNTPYLYFGMWKTSFAWHTEDMDLYSINYL 200 Query: 1517 HWGAPKMWYGVPGKDAVNLESAMRKHLPDLFEEQPDLLHNLVTQFSPSLLKSEGVQAYRC 1696 H+G PK WY VP + LE + P + L + +T SP +LK G+ + Sbjct: 201 HFGEPKSWYSVPPEHGKRLERLAKGFFPGSAQSCEAFLRHKMTLISPLMLKKYGIPFDKV 260 Query: 1697 VQREGEFVLTFPRAYHAGFNCGFNCAEAVNVAPIDWLPVGQNAVELYREQARKITVSHDK 1876 Q GEF++TFP YHAGFN GFNCAE+ N A W+ G+ AV Sbjct: 261 TQEAGEFMITFPYGYHAGFNHGFNCAESTNFATRRWIEYGKQAV---------------- 304 Query: 1877 LLLGAAREAIRAQWDILFLKRNTADNLRWKSVCGPDSTI 1993 L ++ ++ D+ K WK+ G D+T+ Sbjct: 305 -LCSCRKDMVKISMDVFVRKFQPERYKLWKA--GKDNTV 340
>O75164:JHD3A_HUMAN JmjC domain-containing histone demethylation protein 3A - Homo| sapiens (Human) Length = 1064 Score = 157 bits (396), Expect = 5e-37 Identities = 117/399 (29%), Positives = 179/399 (44%), Gaps = 2/399 (0%) Frame = +2 Query: 803 FHPTEEEFKDTLKYIESIRPT-AEPYGICRIVPPPSWKPPCLLKEKSTWENSTFSTRVQK 979 F+PT EEF++ +YI I A G+ ++VPP WKP ++++++ Sbjct: 17 FYPTMEEFRNFSRYIAYIESQGAHRAGLAKVVPPKEWKP------RASYDDIDDLVIPAP 70 Query: 980 VDKLQNRTSSKKSTRGGMMKKRRKLSEPEENSKRFGFEPGPELTLQKFQKYADYFSEQYF 1159 + +L S T+ + KK +T+++F+K A+ S++Y Sbjct: 71 IQQLVTGQSGL-FTQYNIQKKA--------------------MTVREFRKIAN--SDKYC 107 Query: 1160 KKDASMNSLPSVEDIEGEYWR-IVESPTEEIEVIYGADLETGSFGSGFPKLPPETKSDIE 1336 S E++E +YW+ + +P IYGAD+ G+ + K E Sbjct: 108 TPRYS-----EFEELERKYWKNLTFNPP-----IYGADVN----GTLYEKHVDE------ 147 Query: 1337 DKYAHSGWNLNNLPRLQGSVLSFEGGDISGVLVPWVYVGMCFSSFCWHVEDHHLYSLNYL 1516 WN+ L + V G I GV P++Y GM +SF WH ED LYS+NYL Sbjct: 148 -------WNIGRLRTILDLVEKESGITIEGVNTPYLYFGMWKTSFAWHTEDMDLYSINYL 200 Query: 1517 HWGAPKMWYGVPGKDAVNLESAMRKHLPDLFEEQPDLLHNLVTQFSPSLLKSEGVQAYRC 1696 H+G PK WY VP + LE + P + L + +T SP +LK G+ + Sbjct: 201 HFGEPKSWYSVPPEHGKRLERLAKGFFPGSAQSCEAFLRHKMTLISPLMLKKYGIPFDKV 260 Query: 1697 VQREGEFVLTFPRAYHAGFNCGFNCAEAVNVAPIDWLPVGQNAVELYREQARKITVSHDK 1876 Q GEF++TFP YHAGFN GFNCAE+ N A W+ G+ AV Sbjct: 261 TQEAGEFMITFPYGYHAGFNHGFNCAESTNFATRRWIEYGKQAV---------------- 304 Query: 1877 LLLGAAREAIRAQWDILFLKRNTADNLRWKSVCGPDSTI 1993 L ++ ++ D+ K WK+ G D+T+ Sbjct: 305 -LCSCRKDMVKISMDVFVRKFQPERYKLWKA--GKDNTV 340
>Q8BW72:JHD3A_MOUSE JmjC domain-containing histone demethylation protein 3A - Mus| musculus (Mouse) Length = 1064 Score = 156 bits (395), Expect = 6e-37 Identities = 118/400 (29%), Positives = 184/400 (46%), Gaps = 3/400 (0%) Frame = +2 Query: 803 FHPTEEEFKDTLKYIESIRPT-AEPYGICRIVPPPSWKPPCLLKEKSTWENSTFSTRVQK 979 F+PT EEF++ +YI I A G+ ++VPP WKP ++++++ Sbjct: 17 FYPTMEEFRNFSRYIAYIESQGAHRAGLAKVVPPKEWKP------RTSYDDIDDLVIPAP 70 Query: 980 VDKLQNRTSSKKSTRGGMMKKRRKLSEPEENSKRFGFEPGPELTLQKFQKYADYFSEQYF 1159 + +L S T+ + KK +T+++F+K A+ S++Y Sbjct: 71 IQQLVTGQSGL-FTQYNIQKKA--------------------MTVREFRKIAN--SDKYC 107 Query: 1160 KKDASMNSLPSVEDIEGEYWR-IVESPTEEIEVIYGADLETGSFGSGFPKLPPETKSDIE 1336 S E++E +YW+ + +P IYGAD+ G+ + + E Sbjct: 108 TPRYS-----EFEELERKYWKNLTFNPP-----IYGADVN----GTLYEQHVDE------ 147 Query: 1337 DKYAHSGWNLNNLPRLQGSVLSFEGGDISGVLVPWVYVGMCFSSFCWHVEDHHLYSLNYL 1516 WN+ L + V G I GV P++Y GM +SF WH ED LYS+NYL Sbjct: 148 -------WNIGRLKTILDLVEKESGITIEGVNTPYLYFGMWKTSFAWHTEDMDLYSINYL 200 Query: 1517 HWGAPKMWYGVPGKDAVNLESAMRKHLPDLFEEQPDLLHNLVTQFSPSLLKSEGVQAYRC 1696 H+G PK WY VP + LE + P + L + +T SP +LK G+ + Sbjct: 201 HFGEPKSWYSVPPEHGKRLERLAKGFFPGSAQSCEAFLRHKMTLISPLMLKKYGIPFDKV 260 Query: 1697 VQREGEFVLTFPRAYHAGFNCGFNCAEAVNVAPIDWLPVGQNAVELYREQARKITVSHDK 1876 Q GEF++TFP YHAGFN GFNCAE+ N A W+ G+ AV Sbjct: 261 TQEAGEFMITFPYGYHAGFNHGFNCAESTNFATRRWIEYGKQAV---------------- 304 Query: 1877 LLLGAAREAIRAQWDILFLKRNTADNLR-WKSVCGPDSTI 1993 L ++ ++ D+ F++R + + WK+ G DST+ Sbjct: 305 -LCSCRKDMVKISMDV-FVRRFQPERYKLWKA--GKDSTV 340
>Q9V6L0:JHD3B_DROME Probable JmjC domain-containing histone demethylation protein 3B -| Drosophila melanogaster (Fruit fly) Length = 452 Score = 155 bits (393), Expect = 1e-36 Identities = 110/352 (31%), Positives = 163/352 (46%), Gaps = 8/352 (2%) Frame = +2 Query: 800 VFHPTEEEFKDTLKYIESIRPT-AEPYGICRIVPPPSWKPPCLLKEKSTWENSTFSTRVQ 976 VF PT EEFKD KY+ + A G+ ++VPPP W P N T + Sbjct: 11 VFRPTWEEFKDFPKYVAYMESQGAHKAGLAKVVPPPEWVPRRSGYADLDALNVTIPAPIC 70 Query: 977 KVDKLQNRTSSKKSTRGGMMKKRRKLSEPEENSKRFGFEPGPELTLQKFQKYAD---YFS 1147 +V ++ + ++ + P LT+++F + A Y + Sbjct: 71 QV-----------------------VTGKQGYYQQINIQKKP-LTVKQFSELASTERYAT 106 Query: 1148 EQYFKKDASMNSLPSVEDIEGEYWRIVESPTEEIEVIYGADLETGSFGSGFPKLPPETKS 1327 ++F ED+E +YW+ + + IYGAD+ +GS T + Sbjct: 107 PKHF----------DFEDLERKYWKNITY----VAPIYGADV-SGSI----------TDT 141 Query: 1328 DIEDKYAHSGWNLNNLPRLQGSVLSFEGGD----ISGVLVPWVYVGMCFSSFCWHVEDHH 1495 D WN+N L G++L + D I GV ++Y GM ++F WH ED Sbjct: 142 D------QDSWNINRL----GTILDYVNKDYNIQIDGVNTAYLYFGMWKTTFAWHTEDMD 191 Query: 1496 LYSLNYLHWGAPKMWYGVPGKDAVNLESAMRKHLPDLFEEQPDLLHNLVTQFSPSLLKSE 1675 LYS+NYLH+GAPK WY VP + LE ++ P ++ L + +T SP +LK Sbjct: 192 LYSINYLHFGAPKTWYVVPPECGRKLEKVANQYFPASYKNCNAYLRHKMTLISPQILKQH 251 Query: 1676 GVQAYRCVQREGEFVLTFPRAYHAGFNCGFNCAEAVNVAPIDWLPVGQNAVE 1831 V + Q GE ++TFP YHAGFN GFNCAE+ N A W+ G+ AV+ Sbjct: 252 DVPVSKITQEAGEIMITFPFGYHAGFNHGFNCAESTNFAMERWIEYGKRAVQ 303
>Q91VY5:JHD3B_MOUSE JmjC domain-containing histone demethylation protein 3B - Mus| musculus (Mouse) Length = 1086 Score = 154 bits (388), Expect = 4e-36 Identities = 120/416 (28%), Positives = 189/416 (45%), Gaps = 3/416 (0%) Frame = +2 Query: 803 FHPTEEEFKDTLKYIESIRPT-AEPYGICRIVPPPSWKPPCLLKEKSTWENSTFSTRVQK 979 F PT +EF+D +Y+ I A G+ +I+PP WKP + ++ +Q+ Sbjct: 18 FRPTMDEFRDFNRYVAYIESQGAHRAGLAKIIPPKEWKPR---QTYDDIDDVVIPAPIQQ 74 Query: 980 VDKLQNRTSSKKSTRGGMMKKRRKLSEPEENSKRFGFEPGPELTLQKFQKYADYFSEQYF 1159 V Q S T+ + KK +T+ ++++ A+ SE+Y Sbjct: 75 VVTGQ----SGLFTQYNIQKKA--------------------MTVGEYRRLAN--SEKYC 108 Query: 1160 KKDASMNSLPSVEDIEGEYWRIVESPTEEIEVIYGADLETGSFGSGFPKLPPETKSDIED 1339 +D+E +YW+ + + IYGAD+ + +D Sbjct: 109 TPRHQ-----DFDDLERKYWKNLTF----VSPIYGADISGSLY---------------DD 144 Query: 1340 KYAHSGWNLNNLPRLQGSVLSFEGGDISGVLVPWVYVGMCFSSFCWHVEDHHLYSLNYLH 1519 A WN+ NL + V G I GV P++Y GM ++F WH ED LYS+NYLH Sbjct: 145 DVAQ--WNIGNLRTILDMVERECGTIIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLH 202 Query: 1520 WGAPKMWYGVPGKDAVNLESAMRKHLPDLFEEQPDLLHNLVTQFSPSLLKSEGVQAYRCV 1699 +G PK WY +P + LE P + L + +T SP +LK G+ R Sbjct: 203 FGEPKSWYAIPPEHGKRLERLAIGFFPGSSQGCDAFLRHKMTLISPIILKKYGIPFSRIT 262 Query: 1700 QREGEFVLTFPRAYHAGFNCGFNCAEAVNVAPIDWLPVGQNAVE-LYREQARKITVSHDK 1876 Q GEF++TFP YHAGFN GFNCAE+ N A + W+ G+ A + R+ KI++ Sbjct: 263 QEAGEFMITFPYGYHAGFNHGFNCAESTNFATLRWIDYGKVATQCTCRKDMVKISMDVFV 322 Query: 1877 LLLGAAR-EAIRAQWDILFLKRNTADNLRWKSVCGPDSTICKSLKARIETELAQRQ 2041 +L R E + D+ L D+ R ++ P+ + + + I+ +L +RQ Sbjct: 323 RILQPERYEQWKQGRDLTVL-----DHTRPTALSSPELSSWSASRTSIKAKLLRRQ 373
>Q8VCD7:JHD3C_MOUSE JmjC domain-containing histone demethylation protein 3C - Mus| musculus (Mouse) Length = 1054 Score = 152 bits (383), Expect = 2e-35 Identities = 103/344 (29%), Positives = 155/344 (45%), Gaps = 3/344 (0%) Frame = +2 Query: 803 FHPTEEEFKDTLKYIESIRPT-AEPYGICRIVPPPSWKPPCLLKEKSTWENSTFSTRVQK 979 F P+ EEF++ KY+ + A G+ +++PP WKP + +N +Q+ Sbjct: 19 FRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKPRQCYDDI---DNLLIPAPIQQ 75 Query: 980 VDKLQNRTSSKKSTRGGMMKKRRKLSEPEE--NSKRFGFEPGPELTLQKFQKYADYFSEQ 1153 + Q S T+ + KK + E + NS ++ +Y DY Sbjct: 76 MVTGQ----SGLFTQYNIQKKAMTVKEFRQLANSSKYCTP-----------RYLDY---- 116 Query: 1154 YFKKDASMNSLPSVEDIEGEYWRIVESPTEEIEVIYGADLETGSFGSGFPKLPPETKSDI 1333 ED+E +YW+ + + IYGAD+ + G + Sbjct: 117 --------------EDLERKYWKNLTF----VAPIYGADINGSIYDEGVDE--------- 149 Query: 1334 EDKYAHSGWNLNNLPRLQGSVLSFEGGDISGVLVPWVYVGMCFSSFCWHVEDHHLYSLNY 1513 WN+ L + V G I GV P++Y GM ++F WH ED LYS+NY Sbjct: 150 --------WNIARLNTVLDVVEEECGISIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINY 201 Query: 1514 LHWGAPKMWYGVPGKDAVNLESAMRKHLPDLFEEQPDLLHNLVTQFSPSLLKSEGVQAYR 1693 LH+G PK WY +P + LE + P + L + +T SPS+LK G+ + Sbjct: 202 LHFGEPKSWYAIPPEHGKRLERLAQGFFPSSSQGCDAFLRHKMTLISPSVLKKYGIPFDK 261 Query: 1694 CVQREGEFVLTFPRAYHAGFNCGFNCAEAVNVAPIDWLPVGQNA 1825 Q GEF++TFP YHAGFN GFNCAE+ N A + W+ G+ A Sbjct: 262 ITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATVRWIDYGKVA 305
>Q9H3R0:JHD3C_HUMAN JmjC domain-containing histone demethylation protein 3C - Homo| sapiens (Human) Length = 1056 Score = 152 bits (383), Expect = 2e-35 Identities = 102/345 (29%), Positives = 158/345 (45%), Gaps = 4/345 (1%) Frame = +2 Query: 803 FHPTEEEFKDTLKYIESIRPT-AEPYGICRIVPPPSWKPPCLLKEKSTWENSTFSTRVQK 979 F P+ EEF++ KY+ + A G+ +++PP WKP + +N +Q+ Sbjct: 19 FRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKPRQCYDDI---DNLLIPAPIQQ 75 Query: 980 VDKLQNRTSSKKSTRGGMMKKRRKLSEPEENSKRFGFEPGPELTLQKFQKYAD---YFSE 1150 + Q S T+ + KK +T+++F++ A+ Y + Sbjct: 76 MVTGQ----SGLFTQYNIQKKA--------------------MTVKEFRQLANSGKYCTP 111 Query: 1151 QYFKKDASMNSLPSVEDIEGEYWRIVESPTEEIEVIYGADLETGSFGSGFPKLPPETKSD 1330 +Y ED+E +YW+ + + IYGAD+ + G + Sbjct: 112 RYL----------DYEDLERKYWKNLTF----VAPIYGADINGSIYDEGVDE-------- 149 Query: 1331 IEDKYAHSGWNLNNLPRLQGSVLSFEGGDISGVLVPWVYVGMCFSSFCWHVEDHHLYSLN 1510 WN+ L + V G I GV P++Y GM ++F WH ED LYS+N Sbjct: 150 ---------WNIARLNTVLDVVEEECGISIEGVNTPYLYFGMWKTTFAWHTEDMDLYSIN 200 Query: 1511 YLHWGAPKMWYGVPGKDAVNLESAMRKHLPDLFEEQPDLLHNLVTQFSPSLLKSEGVQAY 1690 YLH+G PK WY +P + LE + P + L + +T SPS+LK G+ Sbjct: 201 YLHFGEPKSWYAIPPEHGKRLERLAQGFFPSSSQGCDAFLRHKMTLISPSVLKKYGIPFD 260 Query: 1691 RCVQREGEFVLTFPRAYHAGFNCGFNCAEAVNVAPIDWLPVGQNA 1825 + Q GEF++TFP YHAGFN GFNCAE+ N A + W+ G+ A Sbjct: 261 KITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATVRWIDYGKVA 305
>Q92833:JARD2_HUMAN Protein Jumonji - Homo sapiens (Human)| Length = 1246 Score = 149 bits (377), Expect = 8e-35 Identities = 136/524 (25%), Positives = 229/524 (43%), Gaps = 32/524 (6%) Frame = +2 Query: 959 FSTRVQKVDKLQNRTSSKKSTRGGMMKKRRKLSEPEE-----NSKRFGFEPGPELTLQKF 1123 F +++++V + Q +T ++ +++ + E EE N G ++L F Sbjct: 770 FRSKLKEVGQAQLKTGRRRL----FAQEKEVVKEEEEDKGVLNDFHKCIYKGRSVSLTTF 825 Query: 1124 QKYADYFSEQYFKKDASMNSLPSVEDIEGEYWRIVESPTEEIEVIYGADLETGSFGSGFP 1303 + A F K+ P+ +IE EYWR+VE + V G ++T + GSGFP Sbjct: 826 YRTARNIMSMCFSKE------PAPAEIEQEYWRLVEEKDCHVAVHCGK-VDTNTHGSGFP 878 Query: 1304 KLPPETKSDIEDKYAHSGWNLNNLPRLQGSVLSFEGGDISGVLVPWVYVGMCFSSFCWHV 1483 E ++ GWNL LP GS+L G + GV +PW+ +GM FS+ CW Sbjct: 879 VGKSEP-------FSRHGWNLTVLPNNTGSILRHLGA-VPGVTIPWLNIGMVFSTSCWSR 930 Query: 1484 EDHHLYSLNYLHWGAPKMWYGVPGKDAVNLESAMRKHLPDLFEEQPDLLHNLVTQFSPSL 1663 + +HL ++YLH GA +WY +P ++ LE + L +L + V SP + Sbjct: 931 DQNHLPYIDYLHTGADCIWYCIPAEEENKLEDVVHTLLQANGTPGLQMLESNV-MISPEV 989 Query: 1664 LKSEGVQAYRCVQREGEFVLTFPRAYHAGFNCGFNCAEAVNVAPIDWLPVG-QNAVELYR 1840 L EG++ +R VQ+ G+FV+ FP ++ + CG++ +E V+ A W +G + A E+ R Sbjct: 990 LCKEGIKVHRTVQQSGQFVVCFPGSFVSKVCCGYSVSETVHFATTQWTSMGFETAKEMKR 1049 Query: 1841 EQARKITVSHDKLLLGAAREAIRAQWDILFLKRNTADNLRWKSVCGPD-STICKSLKARI 2017 K S +KLL A+ + K N GP STI L Sbjct: 1050 RHIAK-PFSMEKLLYQIAQAEAK--------KEN-----------GPTLSTISALLDELR 1089 Query: 2018 ETELAQRQNL--------------------CSPSQSRKMDAEFDSADRECAFCYYDLHLS 2137 +TEL QR+ L + + + ++++R C C + +LS Sbjct: 1090 DTELRQRRQLFEAGLHSSARYGSHDGSSTVADGKKKPRKWLQLETSERRCQICQHLCYLS 1149 Query: 2138 A-----SGCPCCPEKYACLLHAKQLCSCDWDKRFFLFRYDVNELNILADALGGKLSAVHR 2302 C E L H ++ SC K ++RYD ++ L + + GK+S + Sbjct: 1150 MVVQENENVVFCLE--CALRHVEKQKSCRGLK--LMYRYDEEQIISLVNQICGKVSGKNG 1205 Query: 2303 WGVSDLGLSLSSCVKREKVQDSKTVRRSTDGPRRSYMSQASTVS 2434 S+ +C+ + + R + D P + +S+ S Sbjct: 1206 --------SIENCLSKPTPKRGPRKRATVDVPPSRLSASSSSKS 1241 Score = 71.6 bits (174), Expect = 3e-11 Identities = 31/72 (43%), Positives = 45/72 (62%) Frame = +2 Query: 785 LDEAPVFHPTEEEFKDTLKYIESIRPTAEPYGICRIVPPPSWKPPCLLKEKSTWENSTFS 964 +DE PV P+ +EF D L YIES+R E +G+CR++PPP W+P C L ++ F Sbjct: 554 MDEIPVLRPSAKEFHDPLIYIESVRAQVEKFGMCRVIPPPDWRPECKLNDE-----MRFV 608 Query: 965 TRVQKVDKLQNR 1000 T++Q + KL R Sbjct: 609 TQIQHIHKLGRR 620
>Q62315:JARD2_MOUSE Protein Jumonji - Mus musculus (Mouse)| Length = 1234 Score = 148 bits (374), Expect = 2e-34 Identities = 124/428 (28%), Positives = 194/428 (45%), Gaps = 27/428 (6%) Frame = +2 Query: 1097 GPELTLQKFQKYADYFSEQYFKKDASMNSLPSVEDIEGEYWRIVESPTEEIEVIYGADLE 1276 G ++L F + A F K+ P+ +IE EYWR+VE + V G ++ Sbjct: 815 GRSVSLTTFYRTARNIMNMCFSKE------PAPAEIEQEYWRLVEEKDCHVAVHCGK-VD 867 Query: 1277 TGSFGSGFPKLPPETKSDIEDKYAHSGWNLNNLPRLQGSVLSFEGGDISGVLVPWVYVGM 1456 T + GSGFP E ++ GWNL LP GS+L G + GV +PW+ +GM Sbjct: 868 TNTHGSGFPVGKSEP-------FSRHGWNLTVLPNNTGSILRHLGA-VPGVTIPWLNIGM 919 Query: 1457 CFSSFCWHVEDHHLYSLNYLHWGAPKMWYGVPGKDAVNLESAMRKHLPDLFEEQPDLLHN 1636 FS+ CW + +HL ++YLH GA +WY +P ++ LE + L +L + Sbjct: 920 VFSTSCWSRDQNHLPYIDYLHTGADCIWYCIPAEEENKLEDVVHTLLQGNGTPGLQMLES 979 Query: 1637 LVTQFSPSLLKSEGVQAYRCVQREGEFVLTFPRAYHAGFNCGFNCAEAVNVAPIDWLPVG 1816 V SP +L +G++ +R VQ+ G+FV+ FP ++ + CG+N +E V+ A W +G Sbjct: 980 NV-MISPEVLCKKGIKVHRTVQQSGQFVVCFPGSFVSKVCCGYNVSETVHFATTQWTSMG 1038 Query: 1817 -QNAVELYREQARKITVSHDKLLLGAAREAIRAQWDILFLKRNTADNLRWKSVCGPD-ST 1990 + A E+ R K S +KLL A+ + K N GP ST Sbjct: 1039 FETAKEMKRRHIAK-PFSMEKLLYQIAQAEAK--------KEN-----------GPTLST 1078 Query: 1991 ICKSLKARIETELAQRQ-----NLCSPSQSRKMDA---------------EFDSADRECA 2110 I L +TEL QR+ L S ++ D + ++++R C Sbjct: 1079 ISALLDELRDTELRQRRLLFEAGLHSSARYGSHDGNSTVADGKKKPRKWLQLETSERRCQ 1138 Query: 2111 FCYYDLHLSA-----SGCPCCPEKYACLLHAKQLCSCDWDKRFFLFRYDVNELNILADAL 2275 C + +LS C E L H ++ SC K ++RYD ++ L + + Sbjct: 1139 ICQHLCYLSMVVQENENVVFCLE--CALRHVEKQKSCRGLK--LMYRYDEEQIISLVNQI 1194 Query: 2276 GGKLSAVH 2299 GK+S H Sbjct: 1195 CGKVSGKH 1202 Score = 73.2 bits (178), Expect = 9e-12 Identities = 32/72 (44%), Positives = 45/72 (62%) Frame = +2 Query: 785 LDEAPVFHPTEEEFKDTLKYIESIRPTAEPYGICRIVPPPSWKPPCLLKEKSTWENSTFS 964 +DE PV P+ +EF D L YIES+R E YG+CR++PPP W+P C L ++ F Sbjct: 552 MDEIPVLRPSAKEFHDPLIYIESVRAQVEKYGMCRVIPPPDWRPECKLNDE-----MRFV 606 Query: 965 TRVQKVDKLQNR 1000 T++Q + KL R Sbjct: 607 TQIQHIHKLGRR 618
>Q9U297:JHD2_CAEEL JmjC domain-containing histone demethylation protein 2 -| Caenorhabditis elegans Length = 894 Score = 134 bits (337), Expect = 3e-30 Identities = 108/359 (30%), Positives = 158/359 (44%), Gaps = 13/359 (3%) Frame = +2 Query: 791 EAPVFHPTEEEFKDTLKYIESIRPTAEPY--GICRIVPPPSWKPPCLLKEKSTWENSTFS 964 E F+PT EFK+ +YI+ I GI +IV P W P K+ S ++ Sbjct: 86 EVLTFYPTMREFKNFSQYIKKIEQNGGHLKAGIAKIVAPEGWTPRPTRKDFSDVDD---- 141 Query: 965 TRVQKVDKLQNRTSSKKSTRGGMMKK----RRKLSEPE----ENSKRFGFEPGPELTLQK 1120 ++ + T G K+ RRK+ E NS ++ P P+L + Sbjct: 142 ---YEITQPARETIEATEKPGAYFKRNVTCRRKMPVREFRTLANSAQYR-NPRPDLKGSE 197 Query: 1121 FQKYADYFSEQYFKKDASMNSLPSVEDIEGEYWRIVESPTEEIEVIYGADLETGSFGSGF 1300 +K+ YF D ++ P IYGAD E GSF Sbjct: 198 IEKH-------YF--DNILHGEP----------------------IYGADTE-GSFYD-- 223 Query: 1301 PKLPPETKSDIEDKYAHSGWNLNNLPRLQGSVLSFEGGDISGVLVPWVYVGMCFSSFCWH 1480 + +E+ WN+N L G++L +I GV ++Y GM ++F WH Sbjct: 224 --------AQVEE------WNMNRL----GTILEDTNYEIKGVNTVYLYFGMYKTTFPWH 265 Query: 1481 VEDHHLYSLNYLHWGAPKMWYGVPGKDAVNLESAMRKHLPDLFEEQPD---LLHNLVTQF 1651 ED LYS+N+LH+GAPK W+ + + A E M + E P L + Sbjct: 266 AEDMDLYSINFLHFGAPKYWFAISSEHADRFERFMSQQFSYQNEYAPQCKAFLRHKTYLV 325 Query: 1652 SPSLLKSEGVQAYRCVQREGEFVLTFPRAYHAGFNCGFNCAEAVNVAPIDWLPVGQNAV 1828 +P LL+ G+ VQR EF++TFPR YH GFN G+N AE+ N A W+ G++AV Sbjct: 326 TPELLRQAGIPYATMVQRPNEFIITFPRGYHMGFNLGYNLAESTNFASQRWIDYGKDAV 384
>Q9V333:JHD3A_DROME Probable JmjC domain-containing histone demethylation protein 3A -| Drosophila melanogaster (Fruit fly) Length = 495 Score = 133 bits (334), Expect = 7e-30 Identities = 99/345 (28%), Positives = 155/345 (44%), Gaps = 4/345 (1%) Frame = +2 Query: 803 FHPTEEEFKDTLKYIESIRPT-AEPYGICRIVPPPSWKPPCLLKEKSTWENSTFSTRVQK 979 F P+ EEF++ YIE I A G+ +I PP W P KS ++ + + Sbjct: 21 FRPSYEEFQNFSAYIEYIESRGAHLAGLAKIQPPAEWVP-----RKSGYDIDNINMTIP- 74 Query: 980 VDKLQNRTSSKKSTRGGMMKKRRKLSEPEENSKRFGFEPGPELTLQKFQKYADYFSEQYF 1159 Q T + + +++RR ++TL++F + Sbjct: 75 APICQVVTGAHGVYQQINIQQRR------------------QMTLRQFME---------- 106 Query: 1160 KKDASMNSLP---SVEDIEGEYWRIVESPTEEIEVIYGADLETGSFGSGFPKLPPETKSD 1330 K ++ ++ P +D+E +YW+ + I +Y AD++ GS D Sbjct: 107 KANSELHQTPRHFDYDDLERKYWKNITY----ISPLYAADVK-GSLSD----------ED 151 Query: 1331 IEDKYAHSGWNLNNLPRLQGSVLSFEGGDISGVLVPWVYVGMCFSSFCWHVEDHHLYSLN 1510 ++ WN+ L + V + I GV ++Y GM SSF WH ED LYS+N Sbjct: 152 LDV------WNIGRLDTILNLVNTDYNIIIDGVNTAYLYFGMWKSSFAWHTEDMDLYSIN 205 Query: 1511 YLHWGAPKMWYGVPGKDAVNLESAMRKHLPDLFEEQPDLLHNLVTQFSPSLLKSEGVQAY 1690 YLH+GAPK WY +P LE + + ++E L + +T SP +L+ + Sbjct: 206 YLHFGAPKTWYAIPPAYGRRLEKLANETFSENYQECNAYLRHKMTMISPKVLRQHNIPYN 265 Query: 1691 RCVQREGEFVLTFPRAYHAGFNCGFNCAEAVNVAPIDWLPVGQNA 1825 + Q GE ++TFP YHAGFN GFN AE+ N A W+ G+ A Sbjct: 266 KITQEAGEIMITFPFGYHAGFNHGFNGAESTNFASKRWIEYGKRA 310
>Q03833:GIS1_YEAST Transcriptional activator/repressor GIS1 - Saccharomyces cerevisiae| (Baker's yeast) Length = 894 Score = 99.0 bits (245), Expect = 2e-19 Identities = 83/347 (23%), Positives = 144/347 (41%), Gaps = 13/347 (3%) Frame = +2 Query: 782 VLDEAPVFHPTEEEFKDTLKYIESIRPTAEPYGICRIVPPPSW------KPPCLLKEKST 943 V+D PVF P+ EF + +I+ I GI +++PP W PP K+ Sbjct: 8 VIDGVPVFKPSMMEFANFQYFIDEITKFGIENGIVKVIPPKEWLELLEGSPPAE-SLKTI 66 Query: 944 WENSTFSTRVQKVDKLQNRTSSKKSTRGGMMKKRRKLSEPEENSKRFGFEPGPELTLQKF 1123 +S + ++ DK +N S E E ++K + L Sbjct: 67 QLDSPIQQQAKRWDKHENGVFS---------------IENEYDNKSYNLTQWKNLAESLD 111 Query: 1124 QKYADY-FSEQYFKKDASMNS------LPSVEDIEGEYWRIVESPTEEIEVIYGADLETG 1282 + + F+++ K++ ++S L ++ +E ++W+ + + Y D + Sbjct: 112 SRISQGDFNDKTLKENCRVDSQQDCYDLAQLQILESDFWKTIAFS----KPFYAVDENSS 167 Query: 1283 SFGSGFPKLPPETKSDIEDKYAHSGWNLNNLPRLQGSVLSFEGGDISGVLVPWVYVGMCF 1462 F Y + WNLNNLP S+ S ++G C Sbjct: 168 IF-----------------PYDLTLWNLNNLP---DSINSSNRRLLTGQ-------SKCI 200 Query: 1463 SSFCWHVEDHHLYSLNYLHWGAPKMWYGVPGKDAVNLESAMRKHLPDLFEEQPDLLHNLV 1642 F WH+++ + S+NYLH+GAPK WY +P + + K E P + + Sbjct: 201 --FPWHLDEQNKCSINYLHFGAPKQWYSIPSANTDQFLKILSKEPSSNKENCPAFIRHQN 258 Query: 1643 TQFSPSLLKSEGVQAYRCVQREGEFVLTFPRAYHAGFNCGFNCAEAV 1783 SP L+ ++ R VQ + EF++TFP ++GFN G+N E++ Sbjct: 259 IITSPDFLRKNNIKFNRVVQFQHEFIITFPYCMYSGFNYGYNFGESI 305
>Q9HDV4:LID2_SCHPO Lid2 complex component lid2 - Schizosaccharomyces pombe (Fission| yeast) Length = 1513 Score = 96.3 bits (238), Expect = 1e-18 Identities = 86/396 (21%), Positives = 160/396 (40%), Gaps = 2/396 (0%) Frame = +2 Query: 1124 QKYADYFSEQYFKKDASMNSLPSVEDIEGEYWRIVESPTEEIEVIYGADLETGSFGSGFP 1303 ++ A+ F+ + +S + + +DIE YW + + L + Sbjct: 337 ERSAEIFNTLGERNSSSKLTNLTEDDIELFYWSSLAESNSGFAPLELEGLSQAYTSTIQS 396 Query: 1304 KLPPETKSDIEDKYAHSGWNLNNLPRLQGSVLSFEGGDISGVLVPWVYVGMCFSSFCWHV 1483 LP + +E KY+ WNL+NLP + ++ D+S + + + +GM F + W Sbjct: 397 SLPSKEVFPLE-KYSSEPWNLHNLPFENPCLFNYSFSDLSSLTITRLSIGMVFYTHGWTK 455 Query: 1484 EDHHLYSLNYLHWGAPKMWYGVPGKDAVNLESAMRKHLPDLFEEQPDLLHNLVTQFSPSL 1663 L++ +G WY +P ++ E + P E + + L SPS Sbjct: 456 SSLSTGLLHHHRFGDTVTWYVLPPDESDAFERYLISSYPQYTMEDLNRSNGLPVIVSPSS 515 Query: 1664 LKSEGVQAYRCVQREGEFVLTFPRAYHAGFNCGFNCAEAVNVAPIDWLPVG--QNAVELY 1837 L G R EF++ P +YH GF+ GF+ E+VN A ++W+ G +++ + Sbjct: 516 LIENGFHPIAIDLRPNEFLVVSPNSYHMGFHQGFSSFESVNFATVNWIKDGLLNSSISVL 575 Query: 1838 REQARKITVSHDKLLLGAAREAIRAQWDILFLKRNTADNLRWKSVCGPDSTICKSLKARI 2017 + +VS++ +++ + L +N + W C D +S Sbjct: 576 KSMRIPSSVSYEAVIIS------------MVLSKNPCFSSEWLIKCFEDMIANESASKN- 622 Query: 2018 ETELAQRQNLCSPSQSRKMDAEFDSADRECAFCYYDLHLSASGCPCCPEKYACLLHAKQL 2197 + L Q+ K+++ R C+ C LS C P+K+ CL + Sbjct: 623 -----EIMKLVPNIQALKLESSVPLEIR-CSNCKQPCFLSFMQCH-EPKKFICLGDCVKE 675 Query: 2198 CSCDWDKRFFLFRYDVNELNILADALGGKLSAVHRW 2305 S + +R+DV+EL+ LA+ + W Sbjct: 676 VSLNATSWMLFYRWDVHELSNLAERFVSLIRGPEEW 711
>Q9UT79:MSC1_SCHPO Multicopy suppressor of chk1 protein 1 - Schizosaccharomyces pombe| (Fission yeast) Length = 1588 Score = 89.7 bits (221), Expect = 9e-17 Identities = 84/317 (26%), Positives = 130/317 (41%), Gaps = 10/317 (3%) Frame = +2 Query: 1334 EDKYAHSGWNLNNLPRLQGSVLSFEGGDISGVLVPWVYVGMCFSSFCWHVEDHHLYSLNY 1513 ++ Y + WNL + + S L F G+L + +G + W + L+ ++Y Sbjct: 480 QNAYYNDPWNLYFIHFSKLSPLRFTP---PGILTSTISLGQPLTCQGWQRDSMSLFGMHY 536 Query: 1514 LHWGAPKMWYGVPGKDAVNLESAMRKHLPDLFEEQPDLLHNLVTQFSPSLLKSEGVQAYR 1693 H+GA ++WY +P D E + P +E+P+ L S+L S G+Q Sbjct: 537 HHYGAQRIWYVIPEVDGPKYEKLLNDLSPSFIQEKPETLIKSKILLPISMLISNGIQVLT 596 Query: 1694 CVQREGEFVLTFPRAYHAGFNCGFNCAEAVNVAPIDWLP--VGQNAVELYREQARKITVS 1867 VQ EFV+T P Y+ + GF+ +E+V A +W+ +N+ +Y+ S Sbjct: 597 FVQNSNEFVITSPNTYYTVLDTGFSLSESVPFATKEWIQDMHAENSFNMYKNLHISAPFS 656 Query: 1868 HDKLLLGAAREAIRAQWDILFLKRNTADNLRWKSVCGPDSTICKSLKARIETELAQRQNL 2047 D +LL A T + W C LK R++ EL R Sbjct: 657 LDHILLANA------------TLDKTVHSAYWLMTC---------LKDRVDRELTLR--- 692 Query: 2048 CSPSQSRK-------MDAEFDSADRECAFCYYDLHLSASGCPCCPEKYACLLHAKQLCSC 2206 ++ RK + +S+ CAFC +L AS K ACL H K C Sbjct: 693 ---NEFRKRHPLLTWIPTPLESSVMACAFCKTFAYL-ASIEEKNGTKTACLSH-KDECFP 747 Query: 2207 DWDKRF-FLFRYDVNEL 2254 + D L RYD N L Sbjct: 748 NTDSDLTVLVRYDDNAL 764
>Q03214:ECM5_YEAST Protein ECM5 - Saccharomyces cerevisiae (Baker's yeast)| Length = 1411 Score = 64.3 bits (155), Expect = 4e-09 Identities = 66/300 (22%), Positives = 106/300 (35%), Gaps = 57/300 (19%) Frame = +2 Query: 1103 ELTLQKFQKYADYFSEQYFKKDASMNSLPSVEDIEGEYWRIVESPTEEIEVIYGADLETG 1282 E +L F F Y A +LP E E Y+ ++ + E+ G L Sbjct: 402 EKSLAVFTAIVAKFGSSYPDLFAKHTTLPQKE-FERLYFHLLSEHFIDFEIDTGLGLPCS 460 Query: 1283 SFGSGFPKLPPETKSDIEDKYAHSG----WNLNNLPRLQGSVLSFEGGDISGVLVPWVYV 1450 G + +K+A WNL+N+P + S+L D++ + Sbjct: 461 MRSPG--------NNSSNEKFAIKNILDQWNLDNIPLNELSLLQHLDLDMANFTRTTYDI 512 Query: 1451 GMCFSSFCWHVEDHHLYSLNYLHWGAPKMWYGVPGKDAVNLES--AMRKHLPDLFEEQP- 1621 GM FS W V DH L S+++ H G+ K+ Y + KD E+ A K D + +P Sbjct: 513 GMLFSCQGWSVSDHFLPSIDFNHLGSTKLVYSIAPKDMEKFEALIARGKSEWDTIQSRPR 572 Query: 1622 ------DLLHNLVTQFSPSLLKSE------------------------------------ 1675 +L + T F S L +E Sbjct: 573 YSTSDDELKSFIETDFYKSFLDAEQSADYSNTGDNSKNSFPEDKIAGNTLHDGSQSDFIF 632 Query: 1676 --------GVQAYRCVQREGEFVLTFPRAYHAGFNCGFNCAEAVNVAPIDWLPVGQNAVE 1831 G++ Y+ Q +G ++ FP+A+ GF ++ AP WL A + Sbjct: 633 EPNFILANGIKLYKTTQEQGSYIFKFPKAFTCSIGSGFYLSQNAKFAPSSWLRFSSEAAK 692
>Q9C5X4:ATX1_ARATH Histone-lysine N-methyltransferase, H3 lysine-4 specific ATX1 -| Arabidopsis thaliana (Mouse-ear cress) Length = 1062 Score = 60.8 bits (146), Expect = 5e-08 Identities = 40/128 (31%), Positives = 69/128 (53%), Gaps = 2/128 (1%) Frame = +2 Query: 3551 VLSGRMWSSGQTIFPKGFKSRVKYWSIVDPVQMAYYFSEIL-DAGLQG-PLFMVTVENCP 3724 V + + I+P+G+ + K+ S+ D A Y E+L DA + PLF+VT ++ Sbjct: 458 VTDSQFFKDENHIWPEGYTAMRKFTSLTDHSASALYKMEVLRDAETKTHPLFIVTADS-- 515 Query: 3725 GEIFINVSPTKCWNMVRERLNMEIRRQLSMGRPNVPTPQPPGSIDGLEMFGLSSPEIVRA 3904 GE F +P+ CWN + R I++ + PN+ + GS G +MFGLS+PE+++ Sbjct: 516 GEQFKGPTPSACWNKIYNR----IKKVQNSDSPNILGEELNGS--GTDMFGLSNPEVIKL 569 Query: 3905 IEVRDRDR 3928 ++ + R Sbjct: 570 VQDLSKSR 577
>O94691:JMJ3_SCHPO Lid2 complex component jmj3 - Schizosaccharomyces pombe (Fission| yeast) Length = 752 Score = 52.0 bits (123), Expect = 2e-05 Identities = 68/327 (20%), Positives = 114/327 (34%), Gaps = 2/327 (0%) Frame = +2 Query: 788 DEAPVFHPTEEEFKDTLKYIESIRPTAEPYGICRIVPPPSWKPPCLLKEKSTWENSTFST 967 D PV P EF D +I + + YG ++V P S P W T Sbjct: 32 DGIPVVEPKISEFVDMESFIRRVERLGKKYGAIKVVRPSSVLNP--------WNEDTMKP 83 Query: 968 RVQKVDKLQNRTSSKKSTRGGMMKKRRKLSEPEENSKRFGFEPGPELTLQKFQKYADYFS 1147 K+D R M++++ + E + + P +K D Sbjct: 84 SDVKMDLWLER----------MVRRKGEYFEIQSDIDHGSAGP---------KKPTDMNV 124 Query: 1148 EQYFKKDA-SMNSLPS-VEDIEGEYWRIVESPTEEIEVIYGADLETGSFGSGFPKLPPET 1321 + F +A S N + V YWR + + + YG T F +P + Sbjct: 125 DDRFPSNAGSSNDFENNVAKAIAYYWRSLTHDS----LWYGY---TNRPSIPFYFIPSIS 177 Query: 1322 KSDIEDKYAHSGWNLNNLPRLQGSVLSFEGGDISGVLVPWVYVGMCFSSFCWHVEDHHLY 1501 + + + S +N P V ++ G ++ W VE L+ Sbjct: 178 AAQKDRVHLRSNTLINTWPN-----------------VGHLFAGKWKTTLPWRVESPELH 220 Query: 1502 SLNYLHWGAPKMWYGVPGKDAVNLESAMRKHLPDLFEEQPDLLHNLVTQFSPSLLKSEGV 1681 ++ G+ WY +P + + + K D D L + F PS L G+ Sbjct: 221 AVQVHLGGSSLQWYVIPSAHSESFKKLAGKLAQDEHWRCSDFLLHQNILFPPSTLVQNGI 280 Query: 1682 QAYRCVQREGEFVLTFPRAYHAGFNCG 1762 Y V ++ E ++TFP +H+ F G Sbjct: 281 VTYSTVLKQDELLITFPGTHHSAFCLG 307
>Q9MA43:ATX2_ARATH Histone-lysine N-methyltransferase ATX2 - Arabidopsis thaliana| (Mouse-ear cress) Length = 1193 Score = 51.2 bits (121), Expect = 4e-05 Identities = 40/146 (27%), Positives = 74/146 (50%), Gaps = 3/146 (2%) Frame = +2 Query: 3482 RGPRIANVVHRFKCSVEPLEIGTVLS-GRMWSSGQTIFPKGFKSRVKYWSIVDPVQMAYY 3658 R + + +HR ++ + +G +++ + + +P+G+ + K+ S+ DP A Y Sbjct: 413 RPTELGDCLHRIG-DLQIINLGRIVTDSEFFKDSKHTWPEGYTATRKFISLKDPNASAMY 471 Query: 3659 FSEIL-DA-GLQGPLFMVTVENCPGEIFINVSPTKCWNMVRERLNMEIRRQLSMGRPNVP 3832 E+L DA P+F VT + GE F +P+ CWN + R+ + Q++ P+V Sbjct: 472 KMEVLRDAESKTRPVFRVTTNS--GEQFKGDTPSACWNKIYNRIK---KIQIASDNPDVL 526 Query: 3833 TPQPPGSIDGLEMFGLSSPEIVRAIE 3910 S G +MFG S+PE+ + I+ Sbjct: 527 GEGLHES--GTDMFGFSNPEVDKLIQ 550
>Q8IRW8:TRR_DROME Histone-lysine N-methyltransferase trr - Drosophila melanogaster| (Fruit fly) Length = 2431 Score = 45.4 bits (106), Expect = 0.002 Identities = 36/144 (25%), Positives = 64/144 (44%), Gaps = 8/144 (5%) Frame = +2 Query: 3536 LEIGTVLSGRM--WSSGQTIFPKGFKSRVKYWSIVDPVQMAYYFSEILDAGLQGPLFMVT 3709 L +G +L ++ + + I+P G+K YW + P + Y I +AG + P F + Sbjct: 2072 LNVGQLLPHQLEAFHTPHYIYPIGYKVSRYYWCVRRPNRRCRYICSIAEAGCK-PEFRIQ 2130 Query: 3710 VENC----PGEIFINVSPTKCWNMVRERLNM--EIRRQLSMGRPNVPTPQPPGSIDGLEM 3871 V++ P F SP+ W + + + ++ + L + P I G ++ Sbjct: 2131 VQDAGDKEPEREFRGSSPSAVWQQILQPITRLRKVHKWLQLF---------PQHISGEDL 2181 Query: 3872 FGLSSPEIVRAIEVRDRDRICTEY 3943 FGL+ P IVR +E T+Y Sbjct: 2182 FGLTEPAIVRILESLPGIETLTDY 2205
>Q66IH2:TBRG1_XENTR Transforming growth factor beta regulated gene 1 - Xenopus tropicalis| (Western clawed frog) (Silurana tropicalis) Length = 409 Score = 45.1 bits (105), Expect = 0.003 Identities = 36/153 (23%), Positives = 67/153 (43%), Gaps = 1/153 (0%) Frame = +2 Query: 3542 IGTVLSGRM-WSSGQTIFPKGFKSRVKYWSIVDPVQMAYYFSEILDAGLQGPLFMVTVEN 3718 +G ++S R + I+P GF S Y + +P Q Y +I D G GP F + ++ Sbjct: 192 LGEIISDRAGFHEKVAIYPVGFCSTRVYVGMKNPDQKCLYTCQIKDGG-TGPQFEIVPDD 250 Query: 3719 CPGEIFINVSPTKCWNMVRERLNMEIRRQLSMGRPNVPTPQPPGSIDGLEMFGLSSPEIV 3898 P + S +C +++ ++++ + ++ S TP + G FG + P I Sbjct: 251 DPQNSIVASSADECHSILLQKISTPLGKRFS-------TP----DLAGAYFFGFTHPTIQ 299 Query: 3899 RAIEVRDRDRICTEYWRYRPHVATGNQHTLPQN 3997 I+ R CT Y + V + +P++ Sbjct: 300 NLIQSCPGARKCTGYQWVKFEVCRAGEEQVPRD 332
>P27546:MAP4_MOUSE Microtubule-associated protein 4 - Mus musculus (Mouse)| Length = 1125 Score = 41.2 bits (95), Expect = 0.039 Identities = 67/286 (23%), Positives = 108/286 (37%), Gaps = 8/286 (2%) Frame = +2 Query: 2312 SDLGLSLSSCVKREKVQDSKTVRRSTDGPRRSYMSQASTVSLVPSLACNEQKDKENKMPS 2491 SDL L L + V ++D TV+ + + PR LA + K + P Sbjct: 548 SDLALPLETKVATVPIKDKGTVQ-TEEKPRED-----------SQLASMQHKGQSTVPPC 595 Query: 2492 LASPEANNACPSVEQRKLGNVSPSKQPSMKDGPSCPTNNDTNRLQYNGGLGDQKSSAPVL 2671 ASPE A + + SP + K+ P + + G+ Q+ + + Sbjct: 596 TASPEPVKAAEQMSTLPIDAPSPLENLEQKETPGSQPSEPCS------GVSRQEEAKAAV 649 Query: 2672 PVXXXXXXXXDVVTTPFNASSEST--KSVHGLAVLKAGRESSLQAGEYRSSLVEHHTRSP 2845 V +TTP N + K LA + + S+ +A +SL + +P Sbjct: 650 GVTGND------ITTPPNKEPPPSPEKKAKPLATTQPAKTSTSKAKTQPTSLPKQP--AP 701 Query: 2846 TMIHDGTNMKPLDSSNTS------HRLIASDSNATLCHSDNHHALITPETKATIMLEKGN 3007 T G N KP+ ++ S R A+ + A P T+A + EK Sbjct: 702 TT-SGGLNKKPMSLASGSVPAAPHKRPAAATATARPSTLPARDVKPKPITEAKVA-EKRT 759 Query: 3008 SQLRTVSSQQFNQNVSWTPSVSQEASSSVFVPIDPSSVKNPHVSFP 3145 S + S+ TP+VS+ S S V PSS ++P + P Sbjct: 760 SPSKPSSAPALKPGPKTTPTVSKATSPSTLVSTGPSS-RSPATTLP 804
>Q3YBR2:TBRG1_HUMAN Transforming growth factor beta regulator 1 - Homo sapiens (Human)| Length = 411 Score = 40.8 bits (94), Expect = 0.051 Identities = 42/157 (26%), Positives = 66/157 (42%), Gaps = 3/157 (1%) Frame = +2 Query: 3542 IGTVLSGRM-WSSGQTIFPKGFKSRVKYWSIVDPVQMAYYFSEILDAGLQGPLFMVTVEN 3718 +G +++ R + I+P G+ S Y S+ P Q Y +I D G+Q P F + E+ Sbjct: 195 LGEIITDRPGFHDESAIYPVGYCSTRIYASMKCPDQKCLYTCQIKDGGVQ-PQFEIVPED 253 Query: 3719 CPGEIFINVSPTKCWNMVRERLNMEIRRQLS--MGRPNVPTPQPPGSIDGLEMFGLSSPE 3892 P ++ S C + E+ R +S MG+ +P P G+ + FG S P Sbjct: 254 DPQNAIVSSSADAC--------HAELLRTISTTMGK-LMPNLLPAGA----DFFGFSHPA 300 Query: 3893 IVRAIEVRDRDRICTEYWRYRPHVATGNQHTLPQNPP 4003 I I+ R C Y + V LP+ P Sbjct: 301 IHNLIQSCPGARKCINYQWVKFDVCKPGDGQLPEGLP 337
>Q5PQK8:TBRG1_RAT Transforming growth factor beta regulated gene 1 - Rattus norvegicus| (Rat) Length = 406 Score = 39.3 bits (90), Expect = 0.15 Identities = 35/135 (25%), Positives = 55/135 (40%), Gaps = 1/135 (0%) Frame = +2 Query: 3542 IGTVLSGRM-WSSGQTIFPKGFKSRVKYWSIVDPVQMAYYFSEILDAGLQGPLFMVTVEN 3718 +G +++ R + I+P G+ S Y S+ P Q Y +I D G+Q P F + E+ Sbjct: 190 LGEIITNRPGFHDENAIYPVGYCSTRVYASMKCPDQKCLYTCQIKDGGVQ-PQFEIVPED 248 Query: 3719 CPGEIFINVSPTKCWNMVRERLNMEIRRQLSMGRPNVPTPQPPGSIDGLEMFGLSSPEIV 3898 P + S C+ E+ R +S + P P G + FG S P I Sbjct: 249 DPRNTIVGSSADACYE--------ELLRAISAATGKL-MPNPLSC--GADFFGFSHPTIH 297 Query: 3899 RAIEVRDRDRICTEY 3943 I+ + C Y Sbjct: 298 NLIQSCPEAQNCVNY 312
>Q3UB74:TBRG1_MOUSE Transforming growth factor beta regulator 1 - Mus musculus (Mouse)| Length = 406 Score = 38.5 bits (88), Expect = 0.25 Identities = 35/135 (25%), Positives = 55/135 (40%), Gaps = 1/135 (0%) Frame = +2 Query: 3542 IGTVLSGRM-WSSGQTIFPKGFKSRVKYWSIVDPVQMAYYFSEILDAGLQGPLFMVTVEN 3718 +G +++ R + I+P G+ S Y S+ P Q Y +I D G+Q P F + E+ Sbjct: 190 LGEIITNRPGFHDENAIYPVGYCSTRVYASMKCPDQKCLYTCQIKDGGVQ-PQFEIVPED 248 Query: 3719 CPGEIFINVSPTKCWNMVRERLNMEIRRQLSMGRPNVPTPQPPGSIDGLEMFGLSSPEIV 3898 P + S C+ E+ R +S + P P G + FG S P I Sbjct: 249 DPQNTIVGSSADACYE--------ELLRAISATTGKL-MPNPLSC--GADFFGFSHPTIH 297 Query: 3899 RAIEVRDRDRICTEY 3943 I+ + C Y Sbjct: 298 NLIQSCPEAQNCVNY 312
>P08640:MUC1_YEAST Mucin-like protein 1 precursor - Saccharomyces cerevisiae (Baker's| yeast) Length = 1367 Score = 37.7 bits (86), Expect = 0.43 Identities = 68/300 (22%), Positives = 114/300 (38%), Gaps = 12/300 (4%) Frame = +2 Query: 2366 SKTVRRSTDGPRRSYMSQASTVSL-VPSLACNEQKDKENKMPSLASPEANNACPSVEQRK 2542 S + S+ P S +++S+ + PS + E PS ++ E+++A Sbjct: 558 SSSTTESSSTPVTSSTTESSSAPVPTPSSSTTESSSAPVPTPSSSTTESSSA-------- 609 Query: 2543 LGNVSPSKQPSMKDGPSCPTNNDTNR-----LQYNGGLGDQKSSAPV-LPVXXXXXXXXD 2704 +P+ S + S P + T + + SSAPV P Sbjct: 610 ---PAPTPSSSTTESSSAPVTSSTTESSSAPVPTPSSSTTESSSAPVPTPSSSTTESSSA 666 Query: 2705 VVTTPFNASSESTKSVHGLAVLKAGRESS---LQAGEYRSSLVEHHTRSPTMIHDGTNMK 2875 V TP ++++ES+ + V + ESS + + SS T S + + Sbjct: 667 PVPTPSSSTTESSSA----PVTSSTTESSSAPVTSSTTESSSAPVPTPSSSTTESSSAPV 722 Query: 2876 PLDSSNTSHRLIASDSNATLCHSDNHHALITPETKATIMLEKGNSQLRTVSSQQFNQNVS 3055 P SS+T+ A + +++ A +T T E ++ + T SS + + Sbjct: 723 PTPSSSTTESSSAPVPTPSSSTTESSSAPVTSSTT-----ESSSAPVPTPSSSTTESSSA 777 Query: 3056 W--TPSVSQEASSSVFVPIDPSSVKNPHVSFPSASVHHGNLTSNQQPNDGWFQRKPESQS 3229 TPS S SSS VP SS V+ N+TS+ P+ F ES S Sbjct: 778 PVPTPSSSTTESSSAPVPTPSSSTTESSVAPVPTPSSSSNITSS-APSSTPFSSSTESSS 836
>P53882:YNR6_YEAST Uncharacterized protein YNL176C - Saccharomyces cerevisiae (Baker's| yeast) Length = 636 Score = 37.4 bits (85), Expect = 0.56 Identities = 60/291 (20%), Positives = 110/291 (37%), Gaps = 9/291 (3%) Frame = +2 Query: 2324 LSLSSCVKREKVQDSKTVRRSTDGPRRSYMSQASTVSLVPSLACNEQKDKENKMPSLASP 2503 ++ +S + R + +S T+ S P S S+++ V + Q+ +P P Sbjct: 1 MNSNSTIGRTTLGESDTISLSFSEPSSSLNSRSTDVVFASTSTLVPQQGSLTSLP----P 56 Query: 2504 EANNACPSVEQRKLG---------NVSPSKQPSMKDGPSCPTNNDTNRLQYNGGLGDQKS 2656 ++ A P+ L +VS + S + DT QY+ Sbjct: 57 VSSTATPTYYSTSLTYDETLHTSIDVSSTSTLVSSTDSSSSSEQDTYSSQYDPATSSYSI 116 Query: 2657 SAPVLPVXXXXXXXXDVVTTPFNASSESTKSVHGLAVLKAGRESSLQAGEYRSSLVEHHT 2836 P + + T+P ++SS T L SS A SS + Sbjct: 117 ITPSMSIFSS--------TSPMSSSSSITSEWSSLTSTTPTLSSS--ATSLSSSWSSLSS 166 Query: 2837 RSPTMIHDGTNMKPLDSSNTSHRLIASDSNATLCHSDNHHALITPETKATIMLEKGNSQL 3016 S ++ ++ L SS + +L + DS +++ S + +I+P + + Q+ Sbjct: 167 PSSLLVSSSLSLS-LSSSYSDTKLFSFDSRSSI-FSPSTPTVISPSYTYLSSISATSFQI 224 Query: 3017 RTVSSQQFNQNVSWTPSVSQEASSSVFVPIDPSSVKNPHVSFPSASVHHGN 3169 T S + SW ++S ++ S PSS +N SF S+S+ N Sbjct: 225 STTSEL----SSSWFSTISSPSTISNKDTTCPSSSRNTSTSFYSSSLSSTN 271
>Q8VQ99:SRAP_STAAU Serine-rich adhesin for platelets precursor - Staphylococcus aureus| Length = 2283 Score = 37.4 bits (85), Expect = 0.56 Identities = 66/315 (20%), Positives = 129/315 (40%), Gaps = 5/315 (1%) Frame = +2 Query: 2309 VSDLG-LSLSSCVKR-EKVQDSKTVRRSTDGPRRSYMSQASTVSLVPSLACNE---QKDK 2473 VSD G LS+S+ +++ E V +S ++ S S +S++S+ SL +E + D Sbjct: 1735 VSDSGSLSVSTSLRKSESVSESSSLSGSQSMSDSVSTSDSSSLSVSMSLRSSESVSESDS 1794 Query: 2474 ENKMPSLASPEANNACPSVEQRKLGNVSPSKQPSMKDGPSCPTNNDTNRLQYNGGLGDQK 2653 + S + + + S+ G+ S S+ S+ D S + T+ G Sbjct: 1795 LSDSKSTSGSTSTSTSGSLSTSLSGSESVSESTSLSDSISMSDSTSTSDSDSLSG-SISL 1853 Query: 2654 SSAPVLPVXXXXXXXXDVVTTPFNASSESTKSVHGLAVLKAGRESSLQAGEYRSSLVEHH 2833 S + L + ++ + SEST + + + SS ++ S + Sbjct: 1854 SGSTSLSTSDSLSDSKSLSSSQSMSGSESTSTS-----VSDSQSSSASNSQFDSMSISAS 1908 Query: 2834 TRSPTMIHDGTNMKPLDSSNTSHRLIASDSNATLCHSDNHHALITPETKATIMLEKGNSQ 3013 D +++ +S++TS L SDS + +L + +I + +S Sbjct: 1909 ESDSVSTSDSSSISGSNSTSTS--LSTSDSMSGSVSVSTSTSL-SDSISGSISVSDSSS- 1964 Query: 3014 LRTVSSQQFNQNVSWTPSVSQEASSSVFVPIDPSSVKNPHVSFPSASVHHGNLTSNQQPN 3193 T +S+ + +++ + S S AS S+ I S + S ++ +L+++ + Sbjct: 1965 --TSTSESLSDSMAQSQSTSTSASGSLSTSISTSMSMSASTSTSQSTSVSTSLSTSDSIS 2022 Query: 3194 DGWFQRKPESQSAVE 3238 D SQSAVE Sbjct: 2023 DSTSISISGSQSAVE 2037
>O14686:MLL2_HUMAN Myeloid/lymphoid or mixed-lineage leukemia protein 2 - Homo sapiens| (Human) Length = 5262 Score = 37.0 bits (84), Expect = 0.73 Identities = 43/167 (25%), Positives = 73/167 (43%), Gaps = 6/167 (3%) Frame = +2 Query: 3479 QRGPRIANVVHRFKCSVEPLE-IGTVLSGRM--WSSGQTIFPKGFKSRVKYWSIVDPVQM 3649 QRG R+ H F+ IG +L +M + S ++P G+++ YWS+ + Sbjct: 4895 QRGERL----HMFRVGGLVFHAIGQLLPHQMADFHSATALYPVGYEATRIYWSLRTNNRR 4950 Query: 3650 AYYFSEILDAGLQGPLFMVTV--ENCPGEIFINVSPTKCWNMVRERLNMEIRRQLSMGRP 3823 Y I + + P F++ V + +F + SP WN + E + +R++ M R Sbjct: 4951 CCYRCSIGENNGR-PEFVIKVIEQGLEDLVFTDASPQAVWNRIIEPV-AAMRKEADMLR- 5007 Query: 3824 NVPTPQPPGSIDGLEMFGLSSPEIVRAIEVRDRDRICTEY-WRYRPH 3961 P + G E+FGL+ ++R E C Y +RY H Sbjct: 5008 -----LFPEYLKGEELFGLTVHAVLRIAESLPGVESCQNYLFRYGRH 5049
>P34239:YKR6_YEAST Uncharacterized protein YKL176C - Saccharomyces cerevisiae (Baker's| yeast) Length = 828 Score = 36.2 bits (82), Expect = 1.2 Identities = 34/131 (25%), Positives = 55/131 (41%), Gaps = 28/131 (21%) Frame = +2 Query: 2909 IASDSNATLCHSDNHHALITPETKATIMLEKGNSQLRTVSSQQFNQNVS----------- 3055 I SDS+A + N++ + PET+ + + N RT ++ N N S Sbjct: 389 IRSDSSAVSRNKSNNNFVDKPETELSTLTSTDNLLSRTENNSNHNYNNSNVSSNSIGSPN 448 Query: 3056 -------W--------TPSVSQEASSSVFVPIDPSSVKNPHVSFPSASVHHGNLTSNQQP 3190 W SVS +S S+ I PSS K+ S+S+H+ + + + QP Sbjct: 449 FHSLRKGWQIPNRRNSNTSVSVSSSESLAEVIQPSSFKS-----GSSSLHYLSSSISSQP 503 Query: 3191 ND--GWFQRKP 3217 WF ++P Sbjct: 504 GSYGSWFNKRP 514
>Q64511:TOP2B_MOUSE DNA topoisomerase 2-beta - Mus musculus (Mouse)| Length = 1612 Score = 35.0 bits (79), Expect = 2.8 Identities = 38/147 (25%), Positives = 61/147 (41%), Gaps = 9/147 (6%) Frame = +2 Query: 965 TRVQKVDKLQNRTSSKKSTRGGMMKKRRKLSEPEENSKRFGFEPGPEL---------TLQ 1117 TRV+K +T++KK +KKR S+ E S+ E P + Sbjct: 1300 TRVRKTPTSTGKTNAKK------VKKRNPWSDDESKSESDLEEAEPVVIPRDSLLRRAAA 1353 Query: 1118 KFQKYADYFSEQYFKKDASMNSLPSVEDIEGEYWRIVESPTEEIEVIYGADLETGSFGSG 1297 + KY FSE+ A+ + +E+++ + I +E G D + +F SG Sbjct: 1354 ERPKYTFDFSEEEDDDAAAADDSNDLEELKVKASPITNDGEDEFVPSDGLDKDEYAFSSG 1413 Query: 1298 FPKLPPETKSDIEDKYAHSGWNLNNLP 1378 K PE S+ DK + NL + P Sbjct: 1414 KSKATPEKSSN--DKKSQDFGNLFSFP 1438
>Q9ESU6:BRD4_MOUSE Bromodomain-containing protein 4 - Mus musculus (Mouse)| Length = 1400 Score = 34.7 bits (78), Expect = 3.6 Identities = 15/27 (55%), Positives = 19/27 (70%), Gaps = 3/27 (11%) Frame = +3 Query: 3255 IHLPQHNMPIHLPQ---HNMPIHLSQH 3326 +HLPQ +P HLPQ H+ P HL+QH Sbjct: 830 LHLPQPELPPHLPQPPEHSTPPHLNQH 856
>O60885:BRD4_HUMAN Bromodomain-containing protein 4 - Homo sapiens (Human)| Length = 1362 Score = 34.7 bits (78), Expect = 3.6 Identities = 15/27 (55%), Positives = 19/27 (70%), Gaps = 3/27 (11%) Frame = +3 Query: 3255 IHLPQHNMPIHLPQ---HNMPIHLSQH 3326 +HLPQ +P HLPQ H+ P HL+QH Sbjct: 828 LHLPQPELPPHLPQPPEHSTPPHLNQH 854
>P22605:RARB_MOUSE Retinoic acid receptor beta - Mus musculus (Mouse)| Length = 482 Score = 34.3 bits (77), Expect = 4.7 Identities = 26/82 (31%), Positives = 36/82 (43%), Gaps = 12/82 (14%) Frame = +2 Query: 3002 GNSQLRTVSSQQFNQNVSWTPSV-----SQEASSSVFVPIDPSSVKNPHVSFP------- 3145 G + RT QF + WTPS+ +Q SS VP PS + P V P Sbjct: 62 GQACQRTTGGSQFAASTKWTPSLNAAIETQSTSSEELVPSPPSPLPPPRVYKPCFVCQDK 121 Query: 3146 SASVHHGNLTSNQQPNDGWFQR 3211 S+ H+G S + G+F+R Sbjct: 122 SSGYHYG--VSACEGCKGFFRR 141
>P52960:PIP2_YEAST Peroxisome proliferation transcriptional regulator - Saccharomyces| cerevisiae (Baker's yeast) Length = 996 Score = 34.3 bits (77), Expect = 4.7 Identities = 29/103 (28%), Positives = 47/103 (45%) Frame = +2 Query: 2324 LSLSSCVKREKVQDSKTVRRSTDGPRRSYMSQASTVSLVPSLACNEQKDKENKMPSLASP 2503 L L+S V+ E V + T+ + AST SL +++ Q ++EN PS+ S Sbjct: 872 LLLNSSVENESVPPYSSSNDPTN------VGNASTYSLAHNIS--NQNNEENMPPSIGSS 923 Query: 2504 EANNACPSVEQRKLGNVSPSKQPSMKDGPSCPTNNDTNRLQYN 2632 E+N A P++ + N + + S NND +L N Sbjct: 924 ESNRAAPNLNFMPINN-------NYNNSGSNINNNDNVKLPSN 959
>P06600:PRP33_DAUCA Proline-rich 33 kDa extensin-related protein precursor - Daucus| carota (Carrot) Length = 211 Score = 33.9 bits (76), Expect = 6.2 Identities = 19/53 (35%), Positives = 26/53 (49%), Gaps = 7/53 (13%) Frame = +3 Query: 3264 PQHNMPIHLPQ-HNMPIH----LSQHNMPIHLL*HNMPIHLPQ--HNIPIHLP 3401 P+H P+H P H P+H ++ + P H PIH PQ H P+H P Sbjct: 96 PEHKPPVHKPPIHKPPVHNTPSVTDDHYPAH------PIHKPQPIHRPPVHKP 142
>Q6BI82:VID21_DEBHA Chromatin modification-related protein VID21 - Debaryomyces hansenii| (Yeast) (Torulaspora hansenii) Length = 1193 Score = 33.9 bits (76), Expect = 6.2 Identities = 64/292 (21%), Positives = 112/292 (38%), Gaps = 16/292 (5%) Frame = +2 Query: 2399 RRSYMSQASTVSLVPSLACNEQKDKENKMPSLASPEANNACPSVEQRKLGNVSPSK-QPS 2575 + +Y++Q +T S + + +QK ++N ++ P + P+V G P + Q Sbjct: 773 QEAYLNQQATRSRMIAAVAQQQKQQQNNQGNIPRPPSQGPGPNV-----GVPPPQRGQIG 827 Query: 2576 MKDGPSCPTNNDTNRLQYNGGLGDQKSSAPVL--PVXXXXXXXXDVVTTPFNASSESTKS 2749 ++ G PTN T G LG+Q P L P+ TTP + + + Sbjct: 828 VQGG---PTNTPT------GSLGNQ---VPPLQQPLQAAQGGMTKRPTTPNGTAYTAEQI 875 Query: 2750 VHGLAVLKAGRESSLQAGEYRSSLVEHHTRSPTMIHDGTNMKPLDSSNTSHRLIASDSNA 2929 L + K R Q ++ + +P ++ + PL S+ T+ SN Sbjct: 876 QQLLQIQKQRRLMQQQNQPGKTGISPSQPNTPALMQN----MPLSSNKTT----VGGSNM 927 Query: 2930 TLCHSDNHHALITPETKATIMLEK---GNSQLRTVSSQQFNQNVSWTPSVSQEASSSVFV 3100 L N +T + +K G SQ + V Q +Q + V S F Sbjct: 928 PLSGMPN----LTQQVSLLQQGQKQQLGPSQRQQVPVSQPSQGQGSSTGVPANKSRIHFA 983 Query: 3101 PIDPSSV------KNPHVSFPS----ASVHHGNLTSNQQPNDGWFQRKPESQ 3226 P S++ KNP+++ A+ + N+ QQ Q++P Q Sbjct: 984 PAQVSAIINSIQTKNPNLTKEQVTKLAATYLANIQQQQQNRANQQQQQPPLQ 1035
>Q4FR69:PYRG_PSYAR CTP synthase - Psychrobacter arcticum| Length = 544 Score = 33.9 bits (76), Expect = 6.2 Identities = 24/83 (28%), Positives = 40/83 (48%), Gaps = 1/83 (1%) Frame = +2 Query: 2750 VHGLAVLKAGRESSLQAGEYRSSLVEHHTRSPTMIHDG-TNMKPLDSSNTSHRLIASDSN 2926 + L ++A R+ ++ G +R+ L+ H T P + G T KP S R I + Sbjct: 148 IESLPFMEAVRQMQVELGRHRAMLM-HLTLVPYIASAGETKTKPTQHSVKELRSIGLQPD 206 Query: 2927 ATLCHSDNHHALITPETKATIML 2995 +C SD+H I+P+ + I L Sbjct: 207 ILICRSDHH---ISPDNRRKIAL 226
>P41624:PSBB_PINTH Photosystem II P680 chlorophyll A apoprotein - Pinus thunbergii| (Green pine) (Japanese black pine) Length = 508 Score = 33.9 bits (76), Expect = 6.2 Identities = 17/58 (29%), Positives = 31/58 (53%) Frame = +2 Query: 1307 LPPETKSDIEDKYAHSGWNLNNLPRLQGSVLSFEGGDISGVLVPWVYVGMCFSSFCWH 1480 +P T+ I+D + SGWN+ + + S+EG ++ + V+ G+CF + WH Sbjct: 63 IPFMTRLGIKDSW--SGWNITGETVINPGIWSYEGVAVAHI----VFSGLCFLAAIWH 114
>Q08427:EGR2_XENLA Early growth response protein 2 - Xenopus laevis (African clawed| frog) Length = 421 Score = 33.5 bits (75), Expect = 8.1 Identities = 33/128 (25%), Positives = 47/128 (36%), Gaps = 6/128 (4%) Frame = -3 Query: 1589 SSLQIPDSQHPFLELHTTSLGHPNAS-SLASINDDLQHA-SRMMKSTCQHRPKAPEHQKC 1416 S L +P S S G PN S S++ DL+H S S+C + P C Sbjct: 118 SLLGVPPSSCSSTSSSNASSGSPNLSCSMSHPQSDLEHIYSPPPYSSCNEIYQDPLRFPC 177 Query: 1415 HHPQKKELSPVVEASCLDSNQNVHTYPQY----LILSQEVTLESHCQKIPSPNQRHRSPL 1248 P L P + +P + + + H + P P RH SPL Sbjct: 178 GSPTAASLPPPPSYPSPKGASDGGMFPMIPDYSALFPPQCQRDLHSDRKPFPCPRHPSPL 237 Query: 1247 SLLWDFPL 1224 S + +F L Sbjct: 238 STIRNFTL 245
>Q00993:UFO_MOUSE Tyrosine-protein kinase receptor UFO precursor - Mus musculus (Mouse)| Length = 888 Score = 33.5 bits (75), Expect = 8.1 Identities = 20/77 (25%), Positives = 31/77 (40%), Gaps = 3/77 (3%) Frame = +2 Query: 2852 IHDGTNMKPLDSSNTSHRLIASDSNATL---CHSDNHHALITPETKATIMLEKGNSQLRT 3022 + D + P+ ++ H L N T C + N + T T +L + L Sbjct: 168 LQDAVPLAPVTGHSSQHSLQTPGLNKTSSFSCEAHNAKGVTTSRTATITVLPQRPHHLHV 227 Query: 3023 VSSQQFNQNVSWTPSVS 3073 VS Q V+WTP +S Sbjct: 228 VSRQPTELEVAWTPGLS 244
>Q63ZM9:CCD16_XENLA Coiled-coil domain-containing protein 16 - Xenopus laevis (African| clawed frog) Length = 356 Score = 33.5 bits (75), Expect = 8.1 Identities = 36/146 (24%), Positives = 63/146 (43%), Gaps = 10/146 (6%) Frame = +2 Query: 923 LLKEKSTWE----NSTFSTRVQKVDKLQNRTSSKKSTRGGMMKKRRKLSEPE--ENSKRF 1084 L+K + W +V ++ + TSS +T +RK SEPE E+ + Sbjct: 53 LIKSELLWPAHILGKQHKEKVAELKGTKATTSSPSNTIEYPRITKRKGSEPEKQESKRTK 112 Query: 1085 GFEPGPELTLQKFQKYADYFSEQYFKKD--ASMNSLPSVEDIEGEYWRIVESPTEEIEVI 1258 G E P + K E++F+K+ +S + PS++ + G+Y + + EE E Sbjct: 113 GSEDHPSASTTKLP-------EEFFEKEKTSSAGNAPSLKLLAGDYEDVDDDDAEEGEEY 165 Query: 1259 YGADLETGSF--GSGFPKLPPETKSD 1330 A + S + P PP + +D Sbjct: 166 ENAKEASSSLLKPAEIPLPPPTSSAD 191 Database: uniprot_sprot.fasta.out Posted date: Jul 19, 2007 5:58 PM Number of letters in database: 100,686,439 Number of sequences in database: 274,295 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 274295 Number of Hits to DB: 823,720,745 Number of extensions: 19241456 Number of successful extensions: 52533 Number of sequences better than 10.0: 64 Number of HSP's gapped: 52355 Number of HSP's successfully gapped: 96 Length of query: 1460 Length of database: 100,686,439 Length adjustment: 126 Effective length of query: 1334 Effective length of database: 66,125,269 Effective search space: 88211108846 Effective search space used: 88211108846 Neighboring words threshold: 12 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
