ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | FLbaf163a20 |
|---|---|
| Clone Library Name | barley_pub |
>P92937:CPK15_ARATH CBL-interacting serine/threonine-protein kinase 15 - Arabidopsis| thaliana (Mouse-ear cress) Length = 421 Score = 516 bits (1328), Expect = e-145 Identities = 256/438 (58%), Positives = 327/438 (74%), Gaps = 1/438 (0%) Frame = +2 Query: 614 EQKGNILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREI 793 E+KG++LM +YE+GK LGQGTFAKVYHAR+++T SVAIKV DKE++LK G+T+QIKREI Sbjct: 2 EKKGSVLMLRYEVGKFLGQGTFAKVYHARHLKTGDSVAIKVIDKERILKVGMTEQIKREI 61 Query: 794 SVMKLVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQRGRLKEDAARKYFQQLICA 973 S M+L++HPNIV+++EVMATK+KIYFV+EHVKGGELFNKV G+L+ED ARKYFQQL+ A Sbjct: 62 SAMRLLRHPNIVELHEVMATKSKIYFVMEHVKGGELFNKVSTGKLREDVARKYFQQLVRA 121 Query: 974 VDFCHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPE 1153 VDFCHSRGV HRDLKPENLLLDE+ NLK+SDFGLS +S+ RR DGLLHT+CGTPAYVAPE Sbjct: 122 VDFCHSRGVCHRDLKPENLLLDEHGNLKISDFGLSALSDSRRQDGLLHTTCGTPAYVAPE 181 Query: 1154 VINRKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXX 1333 VI+R GYDG KAD+WSCGVILFVL+AGYLPF+D NLM +YKKIGKAE K P+W + Sbjct: 182 VISRNGYDGFKADVWSCGVILFVLLAGYLPFRDSNLMELYKKIGKAEVKFPNWLAPGAKR 241 Query: 1334 XXXXXXDPNPSTRISIEKIMEHPWFRKGLDAKLLRYNLQAKDAVPXXXXXXXXXXXXXXX 1513 DPNP+TR+S EKIM+ WFRKGL + ++ +++ + V Sbjct: 242 LLKRILDPNPNTRVSTEKIMKSSWFRKGLQEE-VKESVEEETEVDAEAEGN--------- 291 Query: 1514 XXIEGKEQETKKLSNMNAFDIISLSTGLDLSGMFEDNDKKRESKFTSTNSASTIVSKIED 1693 E+E K+ N+NAF+IISLSTG DLSG+FE ++K E +FTS AS I K+ + Sbjct: 292 ---ASAEKEKKRCINLNAFEIISLSTGFDLSGLFEKGEEKEEMRFTSNREASEITEKLVE 348 Query: 1694 IAKGMQLKLVKKD-GGMLKMEGSKPGRKGVMSIDAEIFEVTPDFHLVELKKTNGDTLEYQ 1870 I K +++K+ KK+ +KM ++AE+FE+ P +H+V LKK+ GDT EY+ Sbjct: 349 IGKDLKMKVRKKEHEWRVKMSAE------ATVVEAEVFEIAPSYHMVVLKKSGGDTAEYK 402 Query: 1871 RVFNQEMRPALKDIVWAW 1924 RV + +RPAL D V AW Sbjct: 403 RVMKESIRPALIDFVLAW 420
>Q6X4A2:CIPK1_ORYSJ CIPK-like protein 1 - Oryza sativa subsp. japonica (Rice)| Length = 449 Score = 438 bits (1126), Expect = e-122 Identities = 226/430 (52%), Positives = 299/430 (69%), Gaps = 4/430 (0%) Frame = +2 Query: 641 KYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHP 820 KYE+G+ +G+GTFAKV A+N E + VAIK+ DKEKV K L +QI+REI MKLVKHP Sbjct: 19 KYELGRTIGEGTFAKVRFAKNTENDEPVAIKILDKEKVQKHRLVEQIRREICTMKLVKHP 78 Query: 821 NIVQMYEVMATKTKIYFVLEHVKGGELFNKVQ-RGRLKEDAARKYFQQLICAVDFCHSRG 997 N+V+++EVM +K +I+ VLE+V GGELF + GRLKE+ ARKYFQQLI AVD+CHSRG Sbjct: 79 NVVRLFEVMGSKARIFIVLEYVTGGELFEIIATNGRLKEEEARKYFQQLINAVDYCHSRG 138 Query: 998 VYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKGYD 1177 VYHRDLK ENLLLD + NLKVSDFGLS ++E + DGLLHT+CGTP YVAPEVI +GYD Sbjct: 139 VYHRDLKLENLLLDASGNLKVSDFGLSALTEQVKADGLLHTTCGTPNYVAPEVIEDRGYD 198 Query: 1178 GAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXXXDP 1357 GA ADIWSCGVIL+VL+AG+LPF+D N++ +YKKI +A+F CPSWFS+ DP Sbjct: 199 GAAADIWSCGVILYVLLAGFLPFEDDNIIALYKKISEAQFTCPSWFSTGAKKLITRILDP 258 Query: 1358 NPSTRISIEKIMEHPWFRKGLDAKLL--RYNLQAKDAVPXXXXXXXXXXXXXXXXXIEGK 1531 NP+TRI+I +I+E PWF+KG + +Y D K Sbjct: 259 NPTTRITISQILEDPWFKKGYKPPVFDEKYETSFDDVDAAFGDSEDRHV----------K 308 Query: 1532 EQETKKLSNMNAFDIISLSTGLDLSGMFE-DNDKKRESKFTSTNSASTIVSKIEDIAKGM 1708 E+ + ++MNAF++ISL+ L+L +FE + KRE++FTS I++KIE+ AK + Sbjct: 309 EETEDQPTSMNAFELISLNQALNLDNLFEAKKEYKRETRFTSQCPPKEIITKIEEAAKPL 368 Query: 1709 QLKLVKKDGGMLKMEGSKPGRKGVMSIDAEIFEVTPDFHLVELKKTNGDTLEYQRVFNQE 1888 + KK+ M +ME K GRKG +++ E+F+V P H+VELKK GDTLE+Q+ F + Sbjct: 369 GFDIQKKNYKM-RMENLKAGRKGNLNVATEVFQVAPSLHVVELKKAKGDTLEFQK-FYRT 426 Query: 1889 MRPALKDIVW 1918 + LKD+VW Sbjct: 427 LSTQLKDVVW 436
>O22932:CPK11_ARATH CBL-interacting serine/threonine-protein kinase 11 - Arabidopsis| thaliana (Mouse-ear cress) Length = 435 Score = 389 bits (999), Expect = e-107 Identities = 203/428 (47%), Positives = 281/428 (65%), Gaps = 4/428 (0%) Frame = +2 Query: 632 LMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKG-GLTDQIKREISVMKL 808 L KYE+GK+LG G FAKV+HAR+ T QSVA+K+ +K+K+L L + IKREIS+M+ Sbjct: 17 LFGKYELGKLLGCGAFAKVFHARDRRTGQSVAVKILNKKKLLTNPALANNIKREISIMRR 76 Query: 809 VKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQR-GRLKEDAARKYFQQLICAVDFC 985 + HPNIV+++EVMATK+KI+F +E VKGGELFNK+ + GRL ED +R+YFQQLI AV +C Sbjct: 77 LSHPNIVKLHEVMATKSKIFFAMEFVKGGELFNKISKHGRLSEDLSRRYFQQLISAVGYC 136 Query: 986 HSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINR 1165 H+RGVYHRDLKPENLL+DEN NLKVSDFGLS +++ R DGLLHT CGTPAYVAPE++++ Sbjct: 137 HARGVYHRDLKPENLLIDENGNLKVSDFGLSALTDQIRPDGLLHTLCGTPAYVAPEILSK 196 Query: 1166 KGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXX 1345 KGY+GAK D+WSCG++LFVL+AGYLPF D N+MNMYKKI K E++ P W S D Sbjct: 197 KGYEGAKVDVWSCGIVLFVLVAGYLPFNDPNVMNMYKKIYKGEYRFPRWMSPDLKRFVSR 256 Query: 1346 XXDPNPSTRISIEKIMEHPWFRKGLDAKLLRYNLQAKDAVPXXXXXXXXXXXXXXXXXIE 1525 D NP TRI+I++I++ PWF +G ++ ++ + +D + Sbjct: 257 LLDINPETRITIDEILKDPWFVRGGFKQIKFHDDEIED---------------------Q 295 Query: 1526 GKEQETKKLSNMNAFDIISLSTGLDLSGMFE--DNDKKRESKFTSTNSASTIVSKIEDIA 1699 E + + ++NAFD+IS S+GLDLSG+F N +F S S + ++E A Sbjct: 296 KVESSLEAVKSLNAFDLISYSSGLDLSGLFAGCSNSSGESERFLSEKSPEMLAEEVEGFA 355 Query: 1700 KGMQLKLVKKDGGMLKMEGSKPGRKGVMSIDAEIFEVTPDFHLVELKKTNGDTLEYQRVF 1879 + L++ KK E G+ G I I + +VE ++ GD Y+ ++ Sbjct: 356 REENLRMKKKKEEEYGFE--MEGQNGKFGIGICISRLNDLLVVVEARRRGGDGDCYKEMW 413 Query: 1880 NQEMRPAL 1903 N ++R L Sbjct: 414 NGKLRVQL 421
>Q9LDI3:CPK24_ARATH CBL-interacting serine/threonine-protein kinase 24 - Arabidopsis| thaliana (Mouse-ear cress) Length = 446 Score = 380 bits (977), Expect = e-104 Identities = 204/433 (47%), Positives = 286/433 (66%), Gaps = 7/433 (1%) Frame = +2 Query: 641 KYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHP 820 KYE+G+ +G+GTFAKV ARN +T +VAIK+ K +LK + DQIKREIS+MK+V+HP Sbjct: 10 KYEVGRTIGEGTFAKVKFARNTDTGDNVAIKIMAKSTILKNRMVDQIKREISIMKIVRHP 69 Query: 821 NIVQMYEVMATKTKIYFVLEHVKGGELFNK-VQRGRLKEDAARKYFQQLICAVDFCHSRG 997 NIV++YEV+A+ +KIY VLE V GGELF++ V +GRL+E +RKYFQQL+ AV CH +G Sbjct: 70 NIVRLYEVLASPSKIYIVLEFVTGGELFDRIVHKGRLEESESRKYFQQLVDAVAHCHCKG 129 Query: 998 VYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDG--LLHTSCGTPAYVAPEVINRKG 1171 VYHRDLKPENLLLD N NLKVSDFGLS + + +G LL T+CGTP YVAPEV++ +G Sbjct: 130 VYHRDLKPENLLLDTNGNLKVSDFGLSALPQ----EGVELLRTTCGTPNYVAPEVLSGQG 185 Query: 1172 YDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXXX 1351 YDG+ ADIWSCGVILFV++AGYLPF + +L +Y+KI AEF CP WFS++ Sbjct: 186 YDGSAADIWSCGVILFVILAGYLPFSETDLPGLYRKINAAEFSCPPWFSAEVKFLIHRIL 245 Query: 1352 DPNPSTRISIEKIMEHPWFRKGLDAKLLRY-NLQAKDAVPXXXXXXXXXXXXXXXXXI-E 1525 DPNP TRI I+ I + PWFR L Y ++A++ + E Sbjct: 246 DPNPKTRIQIQGIKKDPWFR-------LNYVPIRAREEEEVNLDDIRAVFDGIEGSYVAE 298 Query: 1526 GKEQETKKLSNMNAFDIISLSTGLDLSGMFEDNDK--KRESKFTSTNSASTIVSKIEDIA 1699 E+ + MNAF++I+LS GL+LS +F+ KR+++F S S I++ IE +A Sbjct: 299 NVERNDEGPLMMNAFEMITLSQGLNLSALFDRRQDFVKRQTRFVSRREPSEIIANIEAVA 358 Query: 1700 KGMQLKLVKKDGGMLKMEGSKPGRKGVMSIDAEIFEVTPDFHLVELKKTNGDTLEYQRVF 1879 M K ++ ++EG + G +++ EI+EV P +V+++K G+TLEY + F Sbjct: 359 NSMGFKSHTRNF-KTRLEGLSSIKAGQLAVVIEIYEVAPSLFMVDVRKAAGETLEYHK-F 416 Query: 1880 NQEMRPALKDIVW 1918 +++ L++I+W Sbjct: 417 YKKLCSKLENIIW 429
>Q8RWC9:CIPK1_ARATH CBL-interacting serine/threonine-protein kinase 1 - Arabidopsis| thaliana (Mouse-ear cress) Length = 444 Score = 326 bits (835), Expect = 3e-88 Identities = 179/431 (41%), Positives = 265/431 (61%), Gaps = 7/431 (1%) Frame = +2 Query: 641 KYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHP 820 KYE+G+ LG+G F KV A++ + S A+K+ DK ++ + QIKREI +K++KHP Sbjct: 19 KYELGRTLGEGNFGKVKFAKDTVSGHSFAVKIIDKSRIADLNFSLQIKREIRTLKMLKHP 78 Query: 821 NIVQMYEVMATKTKIYFVLEHVKGGELFNK-VQRGRLKEDAARKYFQQLICAVDFCHSRG 997 +IV+++EV+A+KTKI V+E V GGELF++ V G+L E RK FQQLI + +CHS+G Sbjct: 79 HIVRLHEVLASKTKINMVMELVTGGELFDRIVSNGKLTETDGRKMFQQLIDGISYCHSKG 138 Query: 998 VYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKGYD 1177 V+HRDLK EN+LLD ++K++DFGLS + + R DGLLHT+CG+P YVAPEV+ +GYD Sbjct: 139 VFHRDLKLENVLLDAKGHIKITDFGLSALPQHFRDDGLLHTTCGSPNYVAPEVLANRGYD 198 Query: 1178 GAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXXXDP 1357 GA +DIWSCGVIL+V++ G LPF D+NL +Y+KI K + P W S DP Sbjct: 199 GAASDIWSCGVILYVILTGCLPFDDRNLAVLYQKICKGDPPIPRWLSPGARTMIKRMLDP 258 Query: 1358 NPSTRISIEKIMEHPWFRKGLDAKLLRYNLQAKDAVPXXXXXXXXXXXXXXXXXIEGKEQ 1537 NP TRI++ I WF+ L+ ++P E + Sbjct: 259 NPVTRITVVGIKASEWFK-----------LEYIPSIPDDDDEEEVDTDDDAFSIQELGSE 307 Query: 1538 ETKKLSN---MNAFDIISLSTGLDLSGMFE-DNDKKRESKFTSTNSASTIVSKIEDIAKG 1705 E K + +NAF +I +S+ LDLSG FE +N +R +FTS +SA ++ KIE Sbjct: 308 EGKGSDSPTIINAFQLIGMSSFLDLSGFFEQENVSERRIRFTSNSSAKDLLEKIETAVTE 367 Query: 1706 MQLKLVKKDGGMLKMEGSKPGRKGV--MSIDAEIFEVTPDFHLVELKKTNGDTLEYQRVF 1879 M + KK L+++ + +KG +S+ AE+FE+ P ++VEL+K+ GD+ Y++++ Sbjct: 368 MGFSVQKKH-AKLRVKQEERNQKGQVGLSVTAEVFEIKPSLNVVELRKSYGDSCLYRQLY 426 Query: 1880 NQEMRPALKDI 1912 + LKD+ Sbjct: 427 ER----LLKDV 433
>P92958:KIN11_ARATH SNF1-related protein kinase catalytic subunit alpha KIN11 -| Arabidopsis thaliana (Mouse-ear cress) Length = 512 Score = 244 bits (623), Expect = 1e-63 Identities = 121/265 (45%), Positives = 176/265 (66%), Gaps = 2/265 (0%) Frame = +2 Query: 632 LMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLV 811 ++ Y++GK LG G+F KV A ++ T VAIK+ ++ K+ + ++++REI +++L Sbjct: 16 ILPNYKLGKTLGIGSFGKVKIAEHVVTGHKVAIKILNRRKIKNMEMEEKVRREIKILRLF 75 Query: 812 KHPNIVQMYEVMATKTKIYFVLEHVKGGELFNK-VQRGRLKEDAARKYFQQLICAVDFCH 988 HP+I++ YEV+ T + IY V+E+VK GELF+ V++GRL+ED AR +FQQ+I V++CH Sbjct: 76 MHPHIIRQYEVIETTSDIYVVMEYVKSGELFDYIVEKGRLQEDEARNFFQQIISGVEYCH 135 Query: 989 SRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDG-LLHTSCGTPAYVAPEVINR 1165 V HRDLKPENLLLD N+K++DFGLS + DG L TSCG+P Y APEVI+ Sbjct: 136 RNMVVHRDLKPENLLLDSRCNIKIADFGLSNVMR----DGHFLKTSCGSPNYAAPEVISG 191 Query: 1166 KGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXX 1345 K Y G + D+WSCGVIL+ L+ G LPF D+N+ N++KKI + PS SS+ Sbjct: 192 KLYAGPEVDVWSCGVILYALLCGTLPFDDENIPNLFKKIKGGIYTLPSHLSSEARDLIPR 251 Query: 1346 XXDPNPSTRISIEKIMEHPWFRKGL 1420 +P RI+I +I +H WF+ L Sbjct: 252 MLIVDPVKRITIPEIRQHRWFQTHL 276
>Q38997:KIN10_ARATH SNF1-related protein kinase catalytic subunit alpha KIN10 -| Arabidopsis thaliana (Mouse-ear cress) Length = 535 Score = 241 bits (615), Expect = 9e-63 Identities = 119/265 (44%), Positives = 174/265 (65%), Gaps = 2/265 (0%) Frame = +2 Query: 632 LMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLV 811 ++ Y++G+ LG G+F +V A + T VAIK+ ++ K+ + ++++REI +++L Sbjct: 38 ILPNYKLGRTLGIGSFGRVKIAEHALTGHKVAIKILNRRKIKNMEMEEKVRREIKILRLF 97 Query: 812 KHPNIVQMYEVMATKTKIYFVLEHVKGGELFNK-VQRGRLKEDAARKYFQQLICAVDFCH 988 HP+I+++YEV+ T T IY V+E+V GELF+ V++GRL+ED AR +FQQ+I V++CH Sbjct: 98 MHPHIIRLYEVIETPTDIYLVMEYVNSGELFDYIVEKGRLQEDEARNFFQQIISGVEYCH 157 Query: 989 SRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDG-LLHTSCGTPAYVAPEVINR 1165 V HRDLKPENLLLD N+K++DFGLS I DG L TSCG+P Y APEVI+ Sbjct: 158 RNMVVHRDLKPENLLLDSKCNVKIADFGLSNIMR----DGHFLKTSCGSPNYAAPEVISG 213 Query: 1166 KGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXX 1345 K Y G + D+WSCGVIL+ L+ G LPF D+N+ N++KKI + PS S Sbjct: 214 KLYAGPEVDVWSCGVILYALLCGTLPFDDENIPNLFKKIKGGIYTLPSHLSPGARDLIPR 273 Query: 1346 XXDPNPSTRISIEKIMEHPWFRKGL 1420 +P R++I +I +HPWF+ L Sbjct: 274 MLVVDPMKRVTIPEIRQHPWFQAHL 298
>Q8TDC3:BRSK1_HUMAN BR serine/threonine-protein kinase 1 - Homo sapiens (Human)| Length = 794 Score = 237 bits (604), Expect = 2e-61 Identities = 114/259 (44%), Positives = 172/259 (66%), Gaps = 1/259 (0%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 Y + K LG+G V + T Q VAIK+ ++EK+ + L +++REI+++KL++HP+ Sbjct: 50 YRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNREKLSESVLM-KVEREIAILKLIEHPH 108 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNK-VQRGRLKEDAARKYFQQLICAVDFCHSRGV 1000 ++++++V K +Y VLEHV GGELF+ V++GRL ARK+F+Q++ A+DFCHS + Sbjct: 109 VLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCHSYSI 168 Query: 1001 YHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKGYDG 1180 HRDLKPENLLLDE +N++++DFG++++ D LL TSCG+P Y PEVI + YDG Sbjct: 169 CHRDLKPENLLLDEKNNIRIADFGMASLQVG---DSLLETSCGSPHYACPEVIKGEKYDG 225 Query: 1181 AKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXXXDPN 1360 +AD+WSCGVILF L+ G LPF D NL + +K+ + F P + D + Sbjct: 226 RRADMWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVE 285 Query: 1361 PSTRISIEKIMEHPWFRKG 1417 P R+S+E+I +HPW+ G Sbjct: 286 PEKRLSLEQIQKHPWYLGG 304
>Q5RJI5:BRSK1_MOUSE BR serine/threonine-protein kinase 1 - Mus musculus (Mouse)| Length = 778 Score = 236 bits (603), Expect = 2e-61 Identities = 113/259 (43%), Positives = 172/259 (66%), Gaps = 1/259 (0%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 Y + K LG+G V + T Q VA+K+ ++EK+ + L +++REI+++KL++HP+ Sbjct: 34 YRLEKTLGKGQTGLVKLGVHCITGQKVAVKIVNREKLSESVLM-KVEREIAILKLIEHPH 92 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNK-VQRGRLKEDAARKYFQQLICAVDFCHSRGV 1000 ++++++V K +Y VLEHV GGELF+ V++GRL ARK+F+Q++ A+DFCHS + Sbjct: 93 VLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCHSYSI 152 Query: 1001 YHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKGYDG 1180 HRDLKPENLLLDE +N++++DFG++++ D LL TSCG+P Y PEVI + YDG Sbjct: 153 CHRDLKPENLLLDEKNNIRIADFGMASLQVG---DSLLETSCGSPHYACPEVIKGEKYDG 209 Query: 1181 AKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXXXDPN 1360 +AD+WSCGVILF L+ G LPF D NL + +K+ + F P + D + Sbjct: 210 RRADMWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVE 269 Query: 1361 PSTRISIEKIMEHPWFRKG 1417 P R+S+E+I +HPW+ G Sbjct: 270 PEKRLSLEQIQKHPWYLGG 288
>Q69Z98:BRSK2_MOUSE BR serine/threonine-protein kinase 2 - Mus musculus (Mouse)| Length = 735 Score = 231 bits (590), Expect = 7e-60 Identities = 113/259 (43%), Positives = 171/259 (66%), Gaps = 1/259 (0%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 Y + K LG+G V + T Q VAIK+ ++EK+ + L +++REI+++KL++HP+ Sbjct: 20 YRLEKTLGKGQTGLVKLGIHCVTCQKVAIKIVNREKLSESVLM-KVEREIAILKLIEHPH 78 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNK-VQRGRLKEDAARKYFQQLICAVDFCHSRGV 1000 ++++++V K +Y VLEHV GGELF+ V++GRL ARK+F+Q+I A+DFCHS + Sbjct: 79 VLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSI 138 Query: 1001 YHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKGYDG 1180 HRDLKPENLLLDE +N++++DFG++++ D LL TSCG+P Y PEVI + YDG Sbjct: 139 CHRDLKPENLLLDERNNIRIADFGMASLQVG---DSLLETSCGSPHYACPEVIRGEKYDG 195 Query: 1181 AKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXXXDPN 1360 KAD+WSCGVILF L+ G LPF D NL + +K+ + F P + D + + Sbjct: 196 RKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVD 255 Query: 1361 PSTRISIEKIMEHPWFRKG 1417 + R+++E I +H W+ G Sbjct: 256 AARRLTLEHIQKHIWYIGG 274
>Q8IWQ3:BRSK2_HUMAN BR serine/threonine-protein kinase 2 - Homo sapiens (Human)| Length = 736 Score = 231 bits (590), Expect = 7e-60 Identities = 113/259 (43%), Positives = 171/259 (66%), Gaps = 1/259 (0%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 Y + K LG+G V + T Q VAIK+ ++EK+ + L +++REI+++KL++HP+ Sbjct: 19 YRLEKTLGKGQTGLVKLGVHCVTCQKVAIKIVNREKLSESVLM-KVEREIAILKLIEHPH 77 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNK-VQRGRLKEDAARKYFQQLICAVDFCHSRGV 1000 ++++++V K +Y VLEHV GGELF+ V++GRL ARK+F+Q+I A+DFCHS + Sbjct: 78 VLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSI 137 Query: 1001 YHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKGYDG 1180 HRDLKPENLLLDE +N++++DFG++++ D LL TSCG+P Y PEVI + YDG Sbjct: 138 CHRDLKPENLLLDEKNNIRIADFGMASLQVG---DSLLETSCGSPHYACPEVIRGEKYDG 194 Query: 1181 AKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXXXDPN 1360 KAD+WSCGVILF L+ G LPF D NL + +K+ + F P + D + + Sbjct: 195 RKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVD 254 Query: 1361 PSTRISIEKIMEHPWFRKG 1417 + R+++E I +H W+ G Sbjct: 255 AARRLTLEHIQKHIWYIGG 273
>O74536:SNF1_SCHPO SNF1-like protein kinase ssp2 - Schizosaccharomyces pombe (Fission| yeast) Length = 576 Score = 231 bits (588), Expect = 1e-59 Identities = 113/261 (43%), Positives = 172/261 (65%), Gaps = 2/261 (0%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 Y + + LG+G+F KV A + +T Q VA+K ++ + K + +++REIS +KL++HP+ Sbjct: 34 YIIRETLGEGSFGKVKLATHYKTQQKVALKFISRQLLKKSDMHMRVEREISYLKLLRHPH 93 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNK-VQRGRLKEDAARKYFQQLICAVDFCHSRGV 1000 I+++Y+V+ T T I V+E+ GGELF+ V++ R+ ED R++FQQ+ICA+++CH + Sbjct: 94 IIKLYDVITTPTDIVMVIEYA-GGELFDYIVEKKRMTEDEGRRFFQQIICAIEYCHRHKI 152 Query: 1001 YHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDG-LLHTSCGTPAYVAPEVINRKGYD 1177 HRDLKPENLLLD+N N+K++DFGLS I DG L TSCG+P Y APEVIN K Y Sbjct: 153 VHRDLKPENLLLDDNLNVKIADFGLSNI----MTDGNFLKTSCGSPNYAAPEVINGKLYA 208 Query: 1178 GAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXXXDP 1357 G + D+WSCG++L+V++ G LPF D+ + N++KK+ + P + S Sbjct: 209 GPEVDVWSCGIVLYVMLVGRLPFDDEFIPNLFKKVNSCVYVMPDFLSPGAQSLIRRMIVA 268 Query: 1358 NPSTRISIEKIMEHPWFRKGL 1420 +P RI+I++I PWF L Sbjct: 269 DPMQRITIQEIRRDPWFNVNL 289
>O94168:SNF1_CANTR Carbon catabolite derepressing protein kinase - Candida tropicalis| (Yeast) Length = 619 Score = 230 bits (586), Expect = 2e-59 Identities = 116/267 (43%), Positives = 179/267 (67%), Gaps = 2/267 (0%) Frame = +2 Query: 641 KYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHP 820 +Y++ K LG+G+F KV A+++ T Q VA+K+ +++ + K + +++REIS ++L++HP Sbjct: 51 RYQIIKTLGEGSFGKVKLAQHVGTGQKVALKIINRKTLAKSDMQGRVEREISYLRLLRHP 110 Query: 821 NIVQMYEVMATKTKIYFVLEHVKGGELFNK-VQRGRLKEDAARKYFQQLICAVDFCHSRG 997 +I+++Y+V+ +K +I V+E G ELF+ VQRG++ ED AR++FQQ+I AV++CH Sbjct: 111 HIIKLYDVIKSKDEIIMVIEFA-GKELFDYIVQRGKMPEDEARRFFQQIIAAVEYCHRHK 169 Query: 998 VYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDG-LLHTSCGTPAYVAPEVINRKGY 1174 + HRDLKPENLLLD+ N+K++DFGLS I DG L TSCG+P Y APEVI+ K Y Sbjct: 170 IVHRDLKPENLLLDDQLNVKIADFGLSNI----MTDGNFLKTSCGSPNYAAPEVISGKLY 225 Query: 1175 DGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXXXD 1354 G + D+WS GVIL+V++ G LPF D+ + ++KKI + P++ S Sbjct: 226 AGPEVDVWSSGVILYVMLCGRLPFDDEFIPALFKKISNGVYTLPNYLSPGAKHLLTRMLV 285 Query: 1355 PNPSTRISIEKIMEHPWFRKGLDAKLL 1435 NP RI+I +IME WF++ + LL Sbjct: 286 VNPLNRITIHEIMEDEWFKQDMPDYLL 312
>Q95ZQ4:AAPK2_CAEEL 5'-AMP-activated protein kinase catalytic subunit alpha-2 -| Caenorhabditis elegans Length = 626 Score = 229 bits (584), Expect = 4e-59 Identities = 116/271 (42%), Positives = 172/271 (63%), Gaps = 2/271 (0%) Frame = +2 Query: 614 EQKGNILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREI 793 E K I + Y + + LG GTF KV + T VA+K+ +++K+ + +I+REI Sbjct: 77 ELKAQIKIGHYILKETLGVGTFGKVKVGIHETTQYKVAVKILNRQKIKSLDVVGKIRREI 136 Query: 794 SVMKLVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNK-VQRGRLKEDAARKYFQQLIC 970 + L +HP+I+++Y+V++T + I+ ++EHV GGELF+ V+ GRLK AR++FQQ+I Sbjct: 137 QNLSLFRHPHIIRLYQVISTPSDIFMIMEHVSGGELFDYIVKHGRLKTAEARRFFQQIIS 196 Query: 971 AVDFCHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDG-LLHTSCGTPAYVA 1147 VD+CH V HRDLKPENLLLDE +N+K++DFGLS I DG L TSCG+P Y A Sbjct: 197 GVDYCHRHMVVHRDLKPENLLLDEQNNVKIADFGLSNI----MTDGDFLRTSCGSPNYAA 252 Query: 1148 PEVINRKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDX 1327 PEVI+ K Y G + D+WSCGVIL+ L+ G LPF D+++ ++++KI F P + Sbjct: 253 PEVISGKLYAGPEVDVWSCGVILYALLCGTLPFDDEHVPSLFRKIKSGVFPTPDFLERPI 312 Query: 1328 XXXXXXXXDPNPSTRISIEKIMEHPWFRKGL 1420 +P R +I+ ++ H WF+K L Sbjct: 313 VNLLHHMLCVDPMKRATIKDVIAHEWFQKDL 343
>Q00372:SNF1_CANGA Carbon catabolite derepressing protein kinase - Candida glabrata| (Yeast) (Torulopsis glabrata) Length = 612 Score = 229 bits (583), Expect = 5e-59 Identities = 120/285 (42%), Positives = 184/285 (64%), Gaps = 2/285 (0%) Frame = +2 Query: 611 GEQKGNILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKRE 790 G + GN Y++ K LG+G+F KV A ++ T Q VA+K+ +K+ + K + +I+RE Sbjct: 33 GSRVGN-----YQIVKTLGEGSFGKVKLAYHVTTGQKVALKIINKKVLAKSDMQGRIERE 87 Query: 791 ISVMKLVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNK-VQRGRLKEDAARKYFQQLI 967 IS ++L++HP+I+++Y+V+ +K +I V+E+ G ELF+ VQR ++ E AR++FQQ+I Sbjct: 88 ISYLRLLRHPHIIKLYDVIKSKDEIIMVIEYA-GNELFDYIVQRNKMSEQEARRFFQQII 146 Query: 968 CAVDFCHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDG-LLHTSCGTPAYV 1144 AV++CH + HRDLKPENLLLDE+ N+K++DFGLS I DG L TSCG+P Y Sbjct: 147 SAVEYCHRHKIVHRDLKPENLLLDEHLNVKIADFGLSNI----MTDGNFLKTSCGSPNYA 202 Query: 1145 APEVINRKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSD 1324 APEVI+ K Y G + D+WSCGVIL+V++ LPF D+++ ++K I + P + S Sbjct: 203 APEVISGKLYAGPEVDVWSCGVILYVMLCRRLPFDDESIPVLFKNISNGVYTLPKFLSPG 262 Query: 1325 XXXXXXXXXDPNPSTRISIEKIMEHPWFRKGLDAKLLRYNLQAKD 1459 NP RISI +IM+ WF+ L L+ +L+ ++ Sbjct: 263 ASDLIKRMLIVNPLNRISIHEIMQDEWFKVDLAEYLVPQDLKQQE 307
>Q5RD00:AAPK2_PONPY 5'-AMP-activated protein kinase catalytic subunit alpha-2 - Pongo| pygmaeus (Orangutan) Length = 552 Score = 229 bits (583), Expect = 5e-59 Identities = 116/272 (42%), Positives = 172/272 (63%), Gaps = 2/272 (0%) Frame = +2 Query: 623 GNILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVM 802 G + + Y +G LG GTF KV + T VA+K+ +++K+ + +IKREI + Sbjct: 9 GRVKIGHYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNL 68 Query: 803 KLVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKV-QRGRLKEDAARKYFQQLICAVD 979 KL +HP+I+++Y+V++T T + V+E+V GGELF+ + + GR++E AR+ FQQ++ AVD Sbjct: 69 KLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVD 128 Query: 980 FCHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDG-LLHTSCGTPAYVAPEV 1156 +CH V HRDLKPEN+LLD + N K++DFGLS I DG L TSCG+P Y APEV Sbjct: 129 YCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNIMS----DGEFLRTSCGSPNYAAPEV 184 Query: 1157 INRKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXX 1336 I+ + Y G + DIWSCGVIL+ L+ G LPF D+++ ++KKI F P + + Sbjct: 185 ISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVATL 244 Query: 1337 XXXXXDPNPSTRISIEKIMEHPWFRKGLDAKL 1432 +P R +I+ I EH WF++ L + L Sbjct: 245 LMHMLQVDPLKRATIKDIREHEWFKQDLPSYL 276
>P54646:AAPK2_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-2 - Homo| sapiens (Human) Length = 552 Score = 228 bits (580), Expect = 1e-58 Identities = 115/272 (42%), Positives = 172/272 (63%), Gaps = 2/272 (0%) Frame = +2 Query: 623 GNILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVM 802 G + + Y +G LG GTF KV + T VA+K+ +++K+ + +IKREI + Sbjct: 9 GRVKIGHYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNL 68 Query: 803 KLVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKV-QRGRLKEDAARKYFQQLICAVD 979 KL +HP+I+++Y+V++T T + V+E+V GGELF+ + + GR++E AR+ FQQ++ AVD Sbjct: 69 KLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVD 128 Query: 980 FCHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDG-LLHTSCGTPAYVAPEV 1156 +CH V HRDLKPEN+LLD + N K++DFGLS + DG L TSCG+P Y APEV Sbjct: 129 YCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMS----DGEFLRTSCGSPNYAAPEV 184 Query: 1157 INRKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXX 1336 I+ + Y G + DIWSCGVIL+ L+ G LPF D+++ ++KKI F P + + Sbjct: 185 ISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVATL 244 Query: 1337 XXXXXDPNPSTRISIEKIMEHPWFRKGLDAKL 1432 +P R +I+ I EH WF++ L + L Sbjct: 245 LMHMLQVDPLKRATIKDIREHEWFKQDLPSYL 276
>Q09137:AAPK2_RAT 5'-AMP-activated protein kinase catalytic subunit alpha-2 - Rattus| norvegicus (Rat) Length = 552 Score = 227 bits (579), Expect = 1e-58 Identities = 115/272 (42%), Positives = 171/272 (62%), Gaps = 2/272 (0%) Frame = +2 Query: 623 GNILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVM 802 G + + Y +G LG GTF KV + T VA+K+ +++K+ + +IKREI + Sbjct: 9 GRVKIGHYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNL 68 Query: 803 KLVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKV-QRGRLKEDAARKYFQQLICAVD 979 KL +HP+I+++Y+V++T T + V+E+V GGELF+ + + GR++E AR+ FQQ++ AVD Sbjct: 69 KLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEVEARRLFQQILSAVD 128 Query: 980 FCHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDG-LLHTSCGTPAYVAPEV 1156 +CH V HRDLKPEN+LLD N K++DFGLS + DG L TSCG+P Y APEV Sbjct: 129 YCHRHMVVHRDLKPENVLLDAQMNAKIADFGLSNMMS----DGEFLRTSCGSPNYAAPEV 184 Query: 1157 INRKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXX 1336 I+ + Y G + DIWSCGVIL+ L+ G LPF D+++ ++KKI F P + + Sbjct: 185 ISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSIATL 244 Query: 1337 XXXXXDPNPSTRISIEKIMEHPWFRKGLDAKL 1432 +P R +I+ I EH WF++ L + L Sbjct: 245 LMHMLQVDPLKRATIKDIREHEWFKQDLPSYL 276
>Q28948:AAPK2_PIG 5'-AMP-activated protein kinase catalytic subunit alpha-2 - Sus| scrofa (Pig) Length = 552 Score = 227 bits (579), Expect = 1e-58 Identities = 115/272 (42%), Positives = 171/272 (62%), Gaps = 2/272 (0%) Frame = +2 Query: 623 GNILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVM 802 G + + Y +G LG GTF KV + T VA+K+ +++K+ + +IKREI + Sbjct: 9 GRVKIGHYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNL 68 Query: 803 KLVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKV-QRGRLKEDAARKYFQQLICAVD 979 KL +HP+I+++Y+V++T T + V+E+V GGELF+ + + GR++E AR+ FQQ++ AVD Sbjct: 69 KLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVD 128 Query: 980 FCHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDG-LLHTSCGTPAYVAPEV 1156 +CH V HRDLKPEN+LLD N K++DFGLS + DG L TSCG+P Y APEV Sbjct: 129 YCHRHMVVHRDLKPENVLLDAQMNAKIADFGLSNMMS----DGEFLRTSCGSPNYAAPEV 184 Query: 1157 INRKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXX 1336 I+ + Y G + DIWSCGVIL+ L+ G LPF D+++ ++KKI F P + + Sbjct: 185 ISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVATL 244 Query: 1337 XXXXXDPNPSTRISIEKIMEHPWFRKGLDAKL 1432 +P R +I+ I EH WF++ L + L Sbjct: 245 LMHMLQVDPLKRATIKDIREHEWFKQDLPSYL 276
>Q8BRK8:AAPK2_MOUSE 5'-AMP-activated protein kinase catalytic subunit alpha-2 - Mus| musculus (Mouse) Length = 552 Score = 227 bits (579), Expect = 1e-58 Identities = 115/272 (42%), Positives = 171/272 (62%), Gaps = 2/272 (0%) Frame = +2 Query: 623 GNILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVM 802 G + + Y +G LG GTF KV + T VA+K+ +++K+ + +IKREI + Sbjct: 9 GRVKIGHYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNL 68 Query: 803 KLVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKV-QRGRLKEDAARKYFQQLICAVD 979 KL +HP+I+++Y+V++T T + V+E+V GGELF+ + + GR++E AR+ FQQ++ AVD Sbjct: 69 KLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEVEARRLFQQILSAVD 128 Query: 980 FCHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDG-LLHTSCGTPAYVAPEV 1156 +CH V HRDLKPEN+LLD N K++DFGLS + DG L TSCG+P Y APEV Sbjct: 129 YCHRHMVVHRDLKPENVLLDAQMNAKIADFGLSNMMS----DGEFLRTSCGSPNYAAPEV 184 Query: 1157 INRKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXX 1336 I+ + Y G + DIWSCGVIL+ L+ G LPF D+++ ++KKI F P + + Sbjct: 185 ISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPDYLNRSVATL 244 Query: 1337 XXXXXDPNPSTRISIEKIMEHPWFRKGLDAKL 1432 +P R +I+ I EH WF++ L + L Sbjct: 245 LMHMLQVDPLKRATIKDIREHEWFKQDLPSYL 276
>P06782:SNF1_YEAST Carbon catabolite derepressing protein kinase - Saccharomyces| cerevisiae (Baker's yeast) Length = 633 Score = 226 bits (577), Expect = 2e-58 Identities = 118/271 (43%), Positives = 177/271 (65%), Gaps = 2/271 (0%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 Y++ K LG+G+F KV A + T Q VA+K+ +K+ + K + +I+REIS ++L++HP+ Sbjct: 55 YQIVKTLGEGSFGKVKLAYHTTTGQKVALKIINKKVLAKSDMQGRIEREISYLRLLRHPH 114 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNK-VQRGRLKEDAARKYFQQLICAVDFCHSRGV 1000 I+++Y+V+ +K +I V+E+ G ELF+ VQR ++ E AR++FQQ+I AV++CH + Sbjct: 115 IIKLYDVIKSKDEIIMVIEYA-GNELFDYIVQRDKMSEQEARRFFQQIISAVEYCHRHKI 173 Query: 1001 YHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDG-LLHTSCGTPAYVAPEVINRKGYD 1177 HRDLKPENLLLDE+ N+K++DFGLS I DG L TSCG+P Y APEVI+ K Y Sbjct: 174 VHRDLKPENLLLDEHLNVKIADFGLSNI----MTDGNFLKTSCGSPNYAAPEVISGKLYA 229 Query: 1178 GAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXXXDP 1357 G + D+WSCGVIL+V++ LPF D+++ ++K I + P + S Sbjct: 230 GPEVDVWSCGVILYVMLCRRLPFDDESIPVLFKNISNGVYTLPKFLSPGAAGLIKRMLIV 289 Query: 1358 NPSTRISIEKIMEHPWFRKGLDAKLLRYNLQ 1450 NP RISI +IM+ WF+ L LL +L+ Sbjct: 290 NPLNRISIHEIMQDDWFKVDLPEYLLPPDLK 320
>P52497:SNF1_CANAL Carbon catabolite derepressing protein kinase - Candida albicans| (Yeast) Length = 620 Score = 226 bits (577), Expect = 2e-58 Identities = 116/268 (43%), Positives = 181/268 (67%), Gaps = 3/268 (1%) Frame = +2 Query: 641 KYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHP 820 +Y++ K LG+G+F KV A+++ T Q VA+K+ +++ + K + +++REIS ++L++HP Sbjct: 52 RYQILKTLGEGSFGKVKLAQHLGTGQKVALKIINRKTLAKSDMQGRVEREISYLRLLRHP 111 Query: 821 NIVQMYEVMATKTKIYFVLEHVKGGELFNK-VQRGRLKEDAARKYFQQLICAVDFCHSRG 997 +I+++Y+V+ +K +I V+E G ELF+ VQRG++ ED AR++FQQ+I AV++CH Sbjct: 112 HIIKLYDVIKSKDEIIMVIEFA-GKELFDYIVQRGKMPEDEARRFFQQIIAAVEYCHRHK 170 Query: 998 VYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDG-LLHTSCGTPAYV-APEVINRKG 1171 + HRDLKPENLLLD+ N+K++DFGLS I DG L TSCG+P Y+ APEVI+ K Sbjct: 171 IVHRDLKPENLLLDDQLNVKIADFGLSNI----MTDGNFLKTSCGSPNYMPAPEVISGKL 226 Query: 1172 YDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXXX 1351 Y G + D+WS GVIL+V++ G LPF D+ + ++KKI + P++ S+ Sbjct: 227 YAGPEVDVWSAGVILYVMLCGRLPFDDEFIPALFKKISNGVYTLPNYLSAGAKHLLTRML 286 Query: 1352 DPNPSTRISIEKIMEHPWFRKGLDAKLL 1435 NP RI+I +IME WF++ + LL Sbjct: 287 VVNPLNRITIHEIMEDDWFKQDMPDYLL 314
>Q61846:MELK_MOUSE Maternal embryonic leucine zipper kinase - Mus musculus (Mouse)| Length = 643 Score = 221 bits (563), Expect = 1e-56 Identities = 113/259 (43%), Positives = 163/259 (62%), Gaps = 1/259 (0%) Frame = +2 Query: 632 LMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLV 811 L+ YE+ + +G G FAKV A ++ T + VAIK+ DK + G ++K EI +K + Sbjct: 7 LLKYYELYETIGTGGFAKVKLACHVLTGEMVAIKIMDKNAL--GSDLPRVKTEIDALKSL 64 Query: 812 KHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKV-QRGRLKEDAARKYFQQLICAVDFCH 988 +H +I Q+Y V+ TK KI+ VLE+ GGELF+ + + RL E+ R F+Q++ AV + H Sbjct: 65 RHQHICQLYHVLETKNKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQILSAVAYVH 124 Query: 989 SRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRK 1168 S+G HRDLKPENLL DEN LK+ DFGL + + D L T CG+ AY APE+I K Sbjct: 125 SQGYAHRDLKPENLLFDENHKLKLIDFGLCAKPKGNK-DYHLQTCCGSLAYAAPELIQGK 183 Query: 1169 GYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXX 1348 Y G++AD+WS G++L+VLM G+LPF D N+M +YKKI + +++ P W S Sbjct: 184 SYLGSEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYEVPKWLSPSSILLLQQM 243 Query: 1349 XDPNPSTRISIEKIMEHPW 1405 +P RIS+ ++ HPW Sbjct: 244 LQVDPKKRISMRNLLNHPW 262
>P54645:AAPK1_RAT 5'-AMP-activated protein kinase catalytic subunit alpha-1 - Rattus| norvegicus (Rat) Length = 548 Score = 220 bits (560), Expect = 2e-56 Identities = 111/268 (41%), Positives = 168/268 (62%), Gaps = 2/268 (0%) Frame = +2 Query: 623 GNILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVM 802 G + + Y +G LG GTF KV ++ T VA+K+ +++K+ + +I+REI + Sbjct: 9 GRVKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNL 68 Query: 803 KLVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKV-QRGRLKEDAARKYFQQLICAVD 979 KL +HP+I+++Y+V++T + I+ V+E+V GGELF+ + + GRL E +R+ FQQ++ VD Sbjct: 69 KLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVD 128 Query: 980 FCHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDG-LLHTSCGTPAYVAPEV 1156 +CH V HRDLKPEN+LLD + N K++DFGLS + DG L TSCG+P Y APEV Sbjct: 129 YCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMS----DGEFLRTSCGSPNYAAPEV 184 Query: 1157 INRKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXX 1336 I+ + Y G + DIWS GVIL+ L+ G LPF D ++ ++KKI F P + + Sbjct: 185 ISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISL 244 Query: 1337 XXXXXDPNPSTRISIEKIMEHPWFRKGL 1420 +P R +I+ I EH WF++ L Sbjct: 245 LKHMLQVDPMKRATIKDIREHEWFKQDL 272
>Q5RDH5:AAPK1_PONPY 5'-AMP-activated protein kinase catalytic subunit alpha-1 - Pongo| pygmaeus (Orangutan) Length = 550 Score = 220 bits (560), Expect = 2e-56 Identities = 111/268 (41%), Positives = 168/268 (62%), Gaps = 2/268 (0%) Frame = +2 Query: 623 GNILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVM 802 G + + Y +G LG GTF KV ++ T VA+K+ +++K+ + +I+REI + Sbjct: 11 GRVRIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNL 70 Query: 803 KLVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKV-QRGRLKEDAARKYFQQLICAVD 979 KL +HP+I+++Y+V++T + I+ V+E+V GGELF+ + + GRL E +R+ FQQ++ VD Sbjct: 71 KLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVD 130 Query: 980 FCHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDG-LLHTSCGTPAYVAPEV 1156 +CH V HRDLKPEN+LLD + N K++DFGLS + DG L TSCG+P Y APEV Sbjct: 131 YCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMS----DGEFLRTSCGSPNYAAPEV 186 Query: 1157 INRKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXX 1336 I+ + Y G + DIWS GVIL+ L+ G LPF D ++ ++KKI F P + + Sbjct: 187 ISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISL 246 Query: 1337 XXXXXDPNPSTRISIEKIMEHPWFRKGL 1420 +P R +I+ I EH WF++ L Sbjct: 247 LKHMLQVDPMKRATIKDIREHEWFKQDL 274
>Q5EG47:AAPK1_MOUSE 5'-AMP-activated protein kinase catalytic subunit alpha-1 - Mus| musculus (Mouse) Length = 548 Score = 220 bits (560), Expect = 2e-56 Identities = 111/268 (41%), Positives = 168/268 (62%), Gaps = 2/268 (0%) Frame = +2 Query: 623 GNILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVM 802 G + + Y +G LG GTF KV ++ T VA+K+ +++K+ + +I+REI + Sbjct: 9 GRVKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNL 68 Query: 803 KLVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKV-QRGRLKEDAARKYFQQLICAVD 979 KL +HP+I+++Y+V++T + I+ V+E+V GGELF+ + + GRL E +R+ FQQ++ VD Sbjct: 69 KLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVD 128 Query: 980 FCHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDG-LLHTSCGTPAYVAPEV 1156 +CH V HRDLKPEN+LLD + N K++DFGLS + DG L TSCG+P Y APEV Sbjct: 129 YCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMS----DGEFLRTSCGSPNYAAPEV 184 Query: 1157 INRKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXX 1336 I+ + Y G + DIWS GVIL+ L+ G LPF D ++ ++KKI F P + + Sbjct: 185 ISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISL 244 Query: 1337 XXXXXDPNPSTRISIEKIMEHPWFRKGL 1420 +P R +I+ I EH WF++ L Sbjct: 245 LKHMLQVDPMKRAAIKDIREHEWFKQDL 272
>Q13131:AAPK1_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-1 - Homo| sapiens (Human) Length = 550 Score = 220 bits (560), Expect = 2e-56 Identities = 111/268 (41%), Positives = 168/268 (62%), Gaps = 2/268 (0%) Frame = +2 Query: 623 GNILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVM 802 G + + Y +G LG GTF KV ++ T VA+K+ +++K+ + +I+REI + Sbjct: 11 GRVKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNL 70 Query: 803 KLVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKV-QRGRLKEDAARKYFQQLICAVD 979 KL +HP+I+++Y+V++T + I+ V+E+V GGELF+ + + GRL E +R+ FQQ++ VD Sbjct: 71 KLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVD 130 Query: 980 FCHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDG-LLHTSCGTPAYVAPEV 1156 +CH V HRDLKPEN+LLD + N K++DFGLS + DG L TSCG+P Y APEV Sbjct: 131 YCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMS----DGEFLRTSCGSPNYAAPEV 186 Query: 1157 INRKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXX 1336 I+ + Y G + DIWS GVIL+ L+ G LPF D ++ ++KKI F P + + Sbjct: 187 ISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISL 246 Query: 1337 XXXXXDPNPSTRISIEKIMEHPWFRKGL 1420 +P R +I+ I EH WF++ L Sbjct: 247 LKHMLQVDPMKRATIKDIREHEWFKQDL 274
>Q6NSM8:QSK_DANRE Serine/threonine-protein kinase QSK homolog - Danio rerio (Zebrafish)| (Brachydanio rerio) Length = 1187 Score = 219 bits (559), Expect = 3e-56 Identities = 112/259 (43%), Positives = 164/259 (63%), Gaps = 1/259 (0%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 YEM + +G+G FA V A ++ T VAIK+ DK ++ L +I RE+ +MK+++HP+ Sbjct: 59 YEMERTIGKGNFAVVKLATHMITKAKVAIKIVDKTQLDDENLK-KIFREVQIMKMLRHPH 117 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNK-VQRGRLKEDAARKYFQQLICAVDFCHSRGV 1000 I+++Y+VM T+ IY V E+ GGE+F+ V GR+ E AR+ F+Q++ AV FCH R + Sbjct: 118 IIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKDARRKFKQIVAAVYFCHCRSI 177 Query: 1001 YHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKGYDG 1180 HRDLK ENLLLD N N+K++DFG S + +L L T CG+P Y APE+ K YDG Sbjct: 178 VHRDLKAENLLLDHNLNIKIADFGFSNLFSRGQL---LKTWCGSPPYAAPELFEGKEYDG 234 Query: 1181 AKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXXXDPN 1360 K DIWS GV+L+VL+ G LPF L N+ ++ +F+ P + S+D Sbjct: 235 PKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFRIPFFMSTDCEYLIRHMLILE 294 Query: 1361 PSTRISIEKIMEHPWFRKG 1417 PS R+S+E+I ++ W R+G Sbjct: 295 PSRRLSMEQICKNKWMRQG 313
>Q14680:MELK_HUMAN Maternal embryonic leucine zipper kinase - Homo sapiens (Human)| Length = 651 Score = 216 bits (551), Expect = 2e-55 Identities = 113/259 (43%), Positives = 161/259 (62%), Gaps = 1/259 (0%) Frame = +2 Query: 632 LMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLV 811 L+ YE+ + +G G FAKV A +I T + VAIK+ DK + G +IK EI +K + Sbjct: 7 LLKYYELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTL--GSDLPRIKTEIEALKNL 64 Query: 812 KHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKV-QRGRLKEDAARKYFQQLICAVDFCH 988 +H +I Q+Y V+ T KI+ VLE+ GGELF+ + + RL E+ R F+Q++ AV + H Sbjct: 65 RHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVH 124 Query: 989 SRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRK 1168 S+G HRDLKPENLL DE LK+ DFGL + + D L T CG+ AY APE+I K Sbjct: 125 SQGYAHRDLKPENLLFDEYHKLKLIDFGLCAKPKGNK-DYHLQTCCGSLAYAAPELIQGK 183 Query: 1169 GYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXX 1348 Y G++AD+WS G++L+VLM G+LPF D N+M +YKKI + ++ P W S Sbjct: 184 SYLGSEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPKWLSPSSILLLQQM 243 Query: 1349 XDPNPSTRISIEKIMEHPW 1405 +P RIS++ ++ HPW Sbjct: 244 LQVDPKKRISMKNLLNHPW 262
>Q6P4S6:QSK_MOUSE Serine/threonine-protein kinase QSK - Mus musculus (Mouse)| Length = 1311 Score = 216 bits (550), Expect = 3e-55 Identities = 109/259 (42%), Positives = 163/259 (62%), Gaps = 1/259 (0%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 YE+ + +G+G FA V A ++ T VAIK+ DK ++ + L +I RE+ +MK++ HP+ Sbjct: 8 YEIDRTIGKGNFAVVKRATHLVTKAKVAIKIIDKSQLDEENLK-KIFREVQIMKMLCHPH 66 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNK-VQRGRLKEDAARKYFQQLICAVDFCHSRGV 1000 I+++Y+VM T+ IY V E+ GGE+F+ V GR+ E AR+ F+Q++ AV FCH R + Sbjct: 67 IIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVTAVYFCHCRNI 126 Query: 1001 YHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKGYDG 1180 HRDLK ENLLLD N N+K++DFG S + +L L T CG+P Y APE+ K YDG Sbjct: 127 VHRDLKAENLLLDANLNIKIADFGFSNLFTPGQL---LKTWCGSPPYAAPELFEGKEYDG 183 Query: 1181 AKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXXXDPN 1360 K DIWS GV+L+VL+ G LPF L N+ ++ +F+ P + S++ + Sbjct: 184 PKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFRIPFFMSTECEHLIRHMLVLD 243 Query: 1361 PSTRISIEKIMEHPWFRKG 1417 P+ R+S+E+I H W + G Sbjct: 244 PNKRLSMEQICRHKWMKLG 262
>Q9Y2K2:QSK_HUMAN Serine/threonine-protein kinase QSK - Homo sapiens (Human)| Length = 1263 Score = 216 bits (550), Expect = 3e-55 Identities = 109/259 (42%), Positives = 164/259 (63%), Gaps = 1/259 (0%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 YE+ + +G+G FA V A ++ T VAIK+ DK ++ + L +I RE+ +MK++ HP+ Sbjct: 8 YEIDRTIGKGNFAVVKRATHLVTKAKVAIKIIDKTQLDEENLK-KIFREVQIMKMLCHPH 66 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNK-VQRGRLKEDAARKYFQQLICAVDFCHSRGV 1000 I+++Y+VM T+ IY V E+ GGE+F+ V GR+ E AR+ F+Q++ AV FCH R + Sbjct: 67 IIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVTAVYFCHCRNI 126 Query: 1001 YHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKGYDG 1180 HRDLK ENLLLD N N+K++DFG S + +L L T CG+P Y APE+ K YDG Sbjct: 127 VHRDLKAENLLLDANLNIKIADFGFSNLFTPGQL---LKTWCGSPPYAAPELFEGKEYDG 183 Query: 1181 AKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXXXDPN 1360 K DIWS GV+L+VL+ G LPF L N+ ++ +F+ P + S++ + Sbjct: 184 PKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFRIPFFMSTECEHLIRHMLVLD 243 Query: 1361 PSTRISIEKIMEHPWFRKG 1417 P+ R+S+E+I +H W + G Sbjct: 244 PNKRLSMEQICKHKWMKLG 262
>Q02723:RKIN1_SECCE Carbon catabolite derepressing protein kinase - Secale cereale (Rye)| Length = 502 Score = 214 bits (546), Expect = 9e-55 Identities = 114/267 (42%), Positives = 169/267 (63%), Gaps = 5/267 (1%) Frame = +2 Query: 635 MHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKL-- 808 + Y +GK+LG GTFAKV A + T VAIKV ++ ++ + ++ KREI +++L Sbjct: 11 LKNYYLGKILGVGTFAKVIIAEHKHTRHKVAIKVLNRRQMRAPEMEEKAKREIKILRLFI 70 Query: 809 -VKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKV-QRGRLKEDAARKYFQQLICAVDF 982 + HP+I+++YEV+ T I+ V+E+ + G+L + + ++ RL+ED AR+ FQQ+I AV++ Sbjct: 71 DLIHPHIIRVYEVIVTPKDIFVVMEYCQNGDLLDYILEKRRLQEDEARRTFQQIISAVEY 130 Query: 983 CHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDG-LLHTSCGTPAYVAPEVI 1159 CH V HRDLKPENLLLD N+K++DFGLS + DG L TSCG+ Y APEVI Sbjct: 131 CHRNKVVHRDLKPENLLLDSKYNVKLADFGLSNVMH----DGHFLKTSCGSLNYAAPEVI 186 Query: 1160 NRKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXX 1339 + K Y G + D+WSCGVIL+ L+ G +PF D N+ N++KKI + P + S Sbjct: 187 SGKLYAGPEIDVWSCGVILYALLCGAVPFDDDNIPNLFKKIKGGTYILPIYLSDLVRDLI 246 Query: 1340 XXXXDPNPSTRISIEKIMEHPWFRKGL 1420 +P RI+I +I +H WF+ L Sbjct: 247 SRMLIVDPMKRITIGEIRKHSWFQNRL 273
>O08678:MARK1_RAT Serine/threonine-protein kinase MARK1 - Rattus norvegicus (Rat)| Length = 793 Score = 214 bits (544), Expect = 2e-54 Identities = 109/286 (38%), Positives = 174/286 (60%), Gaps = 1/286 (0%) Frame = +2 Query: 584 LPACLPAIMGEQKGNILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKG 763 +P C +I + Y + K +G+G FAKV AR++ T + VA+K+ DK ++ Sbjct: 40 IPRCRNSITSATDEQPHIGNYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPT 99 Query: 764 GLTDQIKREISVMKLVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNK-VQRGRLKEDA 940 L ++ RE+ +MK++ HPNIV+++EV+ T+ +Y V+E+ GGE+F+ V GR+KE Sbjct: 100 SL-QKLFREVRIMKILNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKE 158 Query: 941 ARKYFQQLICAVDFCHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHT 1120 AR F+Q++ AV +CH + + HRDLK ENLLLD + N+K++DFG S + L T Sbjct: 159 ARAKFRQIVSAVQYCHQKCIVHRDLKAENLLLDADMNIKIADFGFSNEFT---VGNKLDT 215 Query: 1121 SCGTPAYVAPEVINRKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFK 1300 CG+P Y APE+ K YDG + D+WS GVIL+ L++G LPF +NL + +++ + +++ Sbjct: 216 FCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYR 275 Query: 1301 CPSWFSSDXXXXXXXXXDPNPSTRISIEKIMEHPWFRKGLDAKLLR 1438 P + S+D NP R S+E+IM+ W G + + L+ Sbjct: 276 VPFYMSTDCENLLKKLLVLNPIKRGSLEQIMKDRWMNVGHEEEELK 321
>Q8VHJ5:MARK1_MOUSE Serine/threonine-protein kinase MARK1 - Mus musculus (Mouse)| Length = 795 Score = 214 bits (544), Expect = 2e-54 Identities = 109/286 (38%), Positives = 174/286 (60%), Gaps = 1/286 (0%) Frame = +2 Query: 584 LPACLPAIMGEQKGNILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKG 763 +P C +I + Y + K +G+G FAKV AR++ T + VA+K+ DK ++ Sbjct: 40 IPRCRNSITSATDEQPHIGNYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPT 99 Query: 764 GLTDQIKREISVMKLVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNK-VQRGRLKEDA 940 L ++ RE+ +MK++ HPNIV+++EV+ T+ +Y V+E+ GGE+F+ V GR+KE Sbjct: 100 SL-QKLFREVRIMKILNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKE 158 Query: 941 ARKYFQQLICAVDFCHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHT 1120 AR F+Q++ AV +CH + + HRDLK ENLLLD + N+K++DFG S + L T Sbjct: 159 ARAKFRQIVSAVQYCHQKCIVHRDLKAENLLLDADMNIKIADFGFSNEFT---VGNKLDT 215 Query: 1121 SCGTPAYVAPEVINRKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFK 1300 CG+P Y APE+ K YDG + D+WS GVIL+ L++G LPF +NL + +++ + +++ Sbjct: 216 FCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYR 275 Query: 1301 CPSWFSSDXXXXXXXXXDPNPSTRISIEKIMEHPWFRKGLDAKLLR 1438 P + S+D NP R S+E+IM+ W G + + L+ Sbjct: 276 VPFYMSTDCENLLKKLLVLNPIKRGSLEQIMKDRWMNVGHEEEELK 321
>Q9P0L2:MARK1_HUMAN Serine/threonine-protein kinase MARK1 - Homo sapiens (Human)| Length = 795 Score = 213 bits (543), Expect = 2e-54 Identities = 109/286 (38%), Positives = 174/286 (60%), Gaps = 1/286 (0%) Frame = +2 Query: 584 LPACLPAIMGEQKGNILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKG 763 +P C +I + Y + K +G+G FAKV AR++ T + VA+K+ DK ++ Sbjct: 40 IPRCRNSITSATDEQPHIGNYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPT 99 Query: 764 GLTDQIKREISVMKLVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNK-VQRGRLKEDA 940 L ++ RE+ +MK++ HPNIV+++EV+ T+ +Y V+E+ GGE+F+ V GR+KE Sbjct: 100 SL-QKLFREVRIMKILNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKE 158 Query: 941 ARKYFQQLICAVDFCHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHT 1120 AR F+Q++ AV +CH + + HRDLK ENLLLD + N+K++DFG S + L T Sbjct: 159 ARAKFRQIVSAVQYCHQKYIVHRDLKAENLLLDGDMNIKIADFGFSNEFT---VGNKLDT 215 Query: 1121 SCGTPAYVAPEVINRKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFK 1300 CG+P Y APE+ K YDG + D+WS GVIL+ L++G LPF +NL + +++ + +++ Sbjct: 216 FCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYR 275 Query: 1301 CPSWFSSDXXXXXXXXXDPNPSTRISIEKIMEHPWFRKGLDAKLLR 1438 P + S+D NP R S+E+IM+ W G + + L+ Sbjct: 276 IPFYMSTDCENLLKKLLVLNPIKRGSLEQIMKDRWMNVGHEEEELK 321
>O08679:MARK2_RAT Serine/threonine-protein kinase MARK2 - Rattus norvegicus (Rat)| Length = 722 Score = 212 bits (540), Expect = 4e-54 Identities = 106/259 (40%), Positives = 164/259 (63%), Gaps = 1/259 (0%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 Y + K +G+G FAKV AR+I T + VA+K+ DK ++ L ++ RE+ +MK++ HPN Sbjct: 53 YRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSL-QKLFREVRIMKVLNHPN 111 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNK-VQRGRLKEDAARKYFQQLICAVDFCHSRGV 1000 IV+++EV+ T+ +Y V+E+ GGE+F+ V GR+KE AR F+Q++ AV +CH + + Sbjct: 112 IVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFI 171 Query: 1001 YHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKGYDG 1180 HRDLK ENLLLD + N+K++DFG S L T CG+P Y APE+ K YDG Sbjct: 172 VHRDLKAENLLLDADMNIKIADFGFSNEFT---FGNKLDTFCGSPPYAAPELFQGKKYDG 228 Query: 1181 AKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXXXDPN 1360 + D+WS GVIL+ L++G LPF +NL + +++ + +++ P + S+D N Sbjct: 229 PEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILN 288 Query: 1361 PSTRISIEKIMEHPWFRKG 1417 PS R ++E+IM+ W G Sbjct: 289 PSKRGTLEQIMKDRWMNVG 307
>Q7KZI7:MARK2_HUMAN Serine/threonine-protein kinase MARK2 - Homo sapiens (Human)| Length = 788 Score = 212 bits (540), Expect = 4e-54 Identities = 106/259 (40%), Positives = 164/259 (63%), Gaps = 1/259 (0%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 Y + K +G+G FAKV AR+I T + VA+K+ DK ++ L ++ RE+ +MK++ HPN Sbjct: 53 YRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSL-QKLFREVRIMKVLNHPN 111 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNK-VQRGRLKEDAARKYFQQLICAVDFCHSRGV 1000 IV+++EV+ T+ +Y V+E+ GGE+F+ V GR+KE AR F+Q++ AV +CH + + Sbjct: 112 IVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFI 171 Query: 1001 YHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKGYDG 1180 HRDLK ENLLLD + N+K++DFG S L T CG+P Y APE+ K YDG Sbjct: 172 VHRDLKAENLLLDADMNIKIADFGFSNEFT---FGNKLDTFCGSPPYAAPELFQGKKYDG 228 Query: 1181 AKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXXXDPN 1360 + D+WS GVIL+ L++G LPF +NL + +++ + +++ P + S+D N Sbjct: 229 PEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILN 288 Query: 1361 PSTRISIEKIMEHPWFRKG 1417 PS R ++E+IM+ W G Sbjct: 289 PSKRGTLEQIMKDRWMNVG 307
>Q8CIP4:MARK4_MOUSE MAP/microtubule affinity-regulating kinase 4 - Mus musculus (Mouse)| Length = 752 Score = 211 bits (538), Expect = 8e-54 Identities = 107/266 (40%), Positives = 166/266 (62%), Gaps = 1/266 (0%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 Y + + +G+G FAKV AR+I T + VAIK+ DK ++ L ++ RE+ +MK + HPN Sbjct: 59 YRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPSSL-QKLFREVRIMKGLNHPN 117 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNK-VQRGRLKEDAARKYFQQLICAVDFCHSRGV 1000 IV+++EV+ T+ +Y V+E+ GE+F+ V GR+KE AR F+Q++ AV +CH + + Sbjct: 118 IVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNI 177 Query: 1001 YHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKGYDG 1180 HRDLK ENLLLD +N+K++DFG S L L T CG+P Y APE+ K YDG Sbjct: 178 VHRDLKAENLLLDAEANIKIADFGFSNEFT---LGSKLDTFCGSPPYAAPELFQGKKYDG 234 Query: 1181 AKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXXXDPN 1360 + DIWS GVIL+ L++G LPF NL + +++ + +++ P + S+D N Sbjct: 235 PEVDIWSLGVILYTLVSGSLPFDGHNLKELRERVLRGKYRVPFYMSTDCESILRRFLVLN 294 Query: 1361 PSTRISIEKIMEHPWFRKGLDAKLLR 1438 P+ R ++E+IM+ W G + + L+ Sbjct: 295 PAKRCTLEQIMKDKWINIGYEGEELK 320
>Q96L34:MARK4_HUMAN MAP/microtubule affinity-regulating kinase 4 - Homo sapiens (Human)| Length = 752 Score = 211 bits (538), Expect = 8e-54 Identities = 107/266 (40%), Positives = 166/266 (62%), Gaps = 1/266 (0%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 Y + + +G+G FAKV AR+I T + VAIK+ DK ++ L ++ RE+ +MK + HPN Sbjct: 59 YRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPSSL-QKLFREVRIMKGLNHPN 117 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNK-VQRGRLKEDAARKYFQQLICAVDFCHSRGV 1000 IV+++EV+ T+ +Y V+E+ GE+F+ V GR+KE AR F+Q++ AV +CH + + Sbjct: 118 IVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNI 177 Query: 1001 YHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKGYDG 1180 HRDLK ENLLLD +N+K++DFG S L L T CG+P Y APE+ K YDG Sbjct: 178 VHRDLKAENLLLDAEANIKIADFGFSNEFT---LGSKLDTFCGSPPYAAPELFQGKKYDG 234 Query: 1181 AKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXXXDPN 1360 + DIWS GVIL+ L++G LPF NL + +++ + +++ P + S+D N Sbjct: 235 PEVDIWSLGVILYTLVSGSLPFDGHNLKELRERVLRGKYRVPFYMSTDCESILRRFLVLN 294 Query: 1361 PSTRISIEKIMEHPWFRKGLDAKLLR 1438 P+ R ++E+IM+ W G + + L+ Sbjct: 295 PAKRCTLEQIMKDKWINIGYEGEELK 320
>Q8VHF0:MARK3_RAT MAP/microtubule affinity-regulating kinase 3 - Rattus norvegicus| (Rat) Length = 797 Score = 211 bits (537), Expect = 1e-53 Identities = 106/266 (39%), Positives = 168/266 (63%), Gaps = 1/266 (0%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 Y + K +G+G FAKV AR+I T + VAIK+ DK ++ L ++ RE+ +MK++ HPN Sbjct: 56 YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSL-QKLFREVRIMKILNHPN 114 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNK-VQRGRLKEDAARKYFQQLICAVDFCHSRGV 1000 IV+++EV+ T+ +Y ++E+ GGE+F+ V GR+KE AR F+Q++ AV +CH + + Sbjct: 115 IVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKRI 174 Query: 1001 YHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKGYDG 1180 HRDLK ENLLLD + N+K++DFG S + L T CG+P Y APE+ K YDG Sbjct: 175 VHRDLKAENLLLDADMNIKITDFGFSNEFT---VGSKLDTFCGSPPYAAPELFQGKKYDG 231 Query: 1181 AKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXXXDPN 1360 + D+WS GVIL+ L++G LPF +NL + +++ + +++ P + S+D N Sbjct: 232 PEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLN 291 Query: 1361 PSTRISIEKIMEHPWFRKGLDAKLLR 1438 P R ++E+IM+ W G + + L+ Sbjct: 292 PVKRGTLEQIMKDRWINAGHEEEELK 317
>Q8CFH6:SN1L2_MOUSE Serine/threonine-protein kinase SNF1-like kinase 2 - Mus musculus| (Mouse) Length = 931 Score = 211 bits (536), Expect = 1e-53 Identities = 110/264 (41%), Positives = 162/264 (61%), Gaps = 1/264 (0%) Frame = +2 Query: 617 QKGNILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREIS 796 Q+G + + Y++ LG+G FA V R+ T VAIK+ DK ++ L ++I RE+ Sbjct: 11 QRGPVRVGFYDIEGTLGKGNFAVVKLGRHRTTKTEVAIKIIDKSQLDAVNL-EKIYREVQ 69 Query: 797 VMKLVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKV-QRGRLKEDAARKYFQQLICA 973 +MK++ HP+I+++Y+VM TK+ +Y V E+ K GE+F+ + GRL E AR+ F Q++ A Sbjct: 70 IMKMLDHPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSA 129 Query: 974 VDFCHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPE 1153 VD+CH R V HRDLK ENLLLD N N+K++DFG + L L T CG+P Y APE Sbjct: 130 VDYCHGRKVVHRDLKAENLLLDNNMNIKIADFGFGNFFKTGEL---LATWCGSPPYAAPE 186 Query: 1154 VINRKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXX 1333 V + Y+G + DIWS GV+L+VL+ G LPF L + +++ + F+ P + S D Sbjct: 187 VFEGQQYEGPQLDIWSMGVVLYVLVCGALPFDGPTLPILRQRVLEGRFRIPYFMSEDCEH 246 Query: 1334 XXXXXXDPNPSTRISIEKIMEHPW 1405 +PS R+SI +I EH W Sbjct: 247 LIRRMLVLDPSKRLSIAQIKEHKW 270
>Q03141:MARK3_MOUSE MAP/microtubule affinity-regulating kinase 3 - Mus musculus (Mouse)| Length = 753 Score = 210 bits (535), Expect = 2e-53 Identities = 105/259 (40%), Positives = 164/259 (63%), Gaps = 1/259 (0%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 Y + K +G+G FAKV AR+I T + VAIK+ DK ++ L ++ RE+ +MK++ HPN Sbjct: 56 YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSL-QKLFREVRIMKILNHPN 114 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNK-VQRGRLKEDAARKYFQQLICAVDFCHSRGV 1000 IV+++EV+ T+ +Y ++E+ GGE+F+ V GR+KE AR F+Q++ AV +CH + + Sbjct: 115 IVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKRI 174 Query: 1001 YHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKGYDG 1180 HRDLK ENLLLD + N+K++DFG S + L T CG+P Y APE+ K YDG Sbjct: 175 VHRDLKAENLLLDADMNIKIADFGFSNEFT---VGSKLDTFCGSPPYAAPELFQGKKYDG 231 Query: 1181 AKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXXXDPN 1360 + D+WS GVIL+ L++G LPF +NL + +++ + +++ P + S+D N Sbjct: 232 PEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLN 291 Query: 1361 PSTRISIEKIMEHPWFRKG 1417 P R ++E+IM+ W G Sbjct: 292 PVKRGTLEQIMKDRWINAG 310
>Q9IA88:SN1L2_CHICK Serine/threonine-protein kinase SNF1-like kinase 2 - Gallus gallus| (Chicken) Length = 798 Score = 209 bits (533), Expect = 3e-53 Identities = 111/275 (40%), Positives = 163/275 (59%), Gaps = 1/275 (0%) Frame = +2 Query: 590 ACLPAIMGEQKGNILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGL 769 A +PA Q + + Y++ + LG+G FA V AR+ T VAIK+ DK ++ L Sbjct: 8 ASVPAPSAAQPRPLRVGFYDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRLDPSNL 67 Query: 770 TDQIKREISVMKLVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKV-QRGRLKEDAAR 946 ++I RE+ +MKL+ HP+I+++Y+VM TK +Y V E K GE+F+ + G L E AR Sbjct: 68 -EKIYREVQIMKLLNHPHIIKLYQVMETKDMLYIVTEFAKNGEMFDHLTSNGHLSESEAR 126 Query: 947 KYFQQLICAVDFCHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSC 1126 K F Q++ AV++CHS + HRDLK ENLLLD N N+K++DFG + L T C Sbjct: 127 KKFWQILSAVEYCHSHHIVHRDLKTENLLLDANMNIKLADFGFGNFYKSGEP---LSTWC 183 Query: 1127 GTPAYVAPEVINRKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCP 1306 G+P Y APEV K Y+G DIWS GV+L+VL+ G LPF NL + +++ + F+ P Sbjct: 184 GSPPYAAPEVFEGKEYEGPHLDIWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIP 243 Query: 1307 SWFSSDXXXXXXXXXDPNPSTRISIEKIMEHPWFR 1411 + S D +P+ RI+I +I +H W + Sbjct: 244 YFMSEDCETLIRRMLVVDPTKRITISQIKQHKWMQ 278
>Q05512:MARK2_MOUSE Serine/threonine-protein kinase MARK2 - Mus musculus (Mouse)| Length = 776 Score = 209 bits (532), Expect = 4e-53 Identities = 105/259 (40%), Positives = 163/259 (62%), Gaps = 1/259 (0%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 Y + K +G+G FAKV AR+I T + VA+K+ DK ++ L ++ RE+ +MK++ HPN Sbjct: 53 YRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSL-QKLFREVRIMKVLNHPN 111 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNK-VQRGRLKEDAARKYFQQLICAVDFCHSRGV 1000 IV+++EV+ T+ +Y V+E+ GGE+F+ V GR+KE AR F+Q++ AV +CH + + Sbjct: 112 IVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFI 171 Query: 1001 YHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKGYDG 1180 HRDLK ENLLLD + N+K++DFG S L T CG+P Y APE+ K DG Sbjct: 172 VHRDLKAENLLLDADMNIKIADFGFSNEFT---FGNKLDTFCGSPPYAAPELFQGKKIDG 228 Query: 1181 AKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXXXDPN 1360 + D+WS GVIL+ L++G LPF +NL + +++ + +++ P + S+D N Sbjct: 229 PEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILN 288 Query: 1361 PSTRISIEKIMEHPWFRKG 1417 PS R ++E+IM+ W G Sbjct: 289 PSKRGTLEQIMKDRWMNVG 307
>Q9H0K1:SN1L2_HUMAN Serine/threonine-protein kinase SNF1-like kinase 2 - Homo sapiens| (Human) Length = 926 Score = 208 bits (530), Expect = 6e-53 Identities = 108/264 (40%), Positives = 162/264 (61%), Gaps = 1/264 (0%) Frame = +2 Query: 617 QKGNILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREIS 796 Q+G + + Y++ LG+G FA V R+ T VAIK+ DK ++ L ++I RE+ Sbjct: 11 QRGPVRVGFYDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDAVNL-EKIYREVQ 69 Query: 797 VMKLVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKV-QRGRLKEDAARKYFQQLICA 973 +MK++ HP+I+++Y+VM TK+ +Y V E+ K GE+F+ + GRL E AR+ F Q++ A Sbjct: 70 IMKMLDHPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSA 129 Query: 974 VDFCHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPE 1153 VD+CH R + HRDLK ENLLLD N N+K++DFG + L L T CG+P Y APE Sbjct: 130 VDYCHGRKIVHRDLKAENLLLDNNMNIKIADFGFGNFFKSGEL---LATWCGSPPYAAPE 186 Query: 1154 VINRKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXX 1333 V + Y+G + DIWS GV+L+VL+ G LPF L + +++ + F+ P + S D Sbjct: 187 VFEGQQYEGPQLDIWSMGVVLYVLVCGALPFDGPTLPILRQRVLEGRFRIPYFMSEDCEH 246 Query: 1334 XXXXXXDPNPSTRISIEKIMEHPW 1405 +PS R++I +I EH W Sbjct: 247 LIRRMLVLDPSKRLTIAQIKEHKW 270
>Q12263:GIN4_YEAST Serine/threonine-protein kinase GIN4 - Saccharomyces cerevisiae| (Baker's yeast) Length = 1142 Score = 206 bits (525), Expect = 2e-52 Identities = 112/276 (40%), Positives = 163/276 (59%), Gaps = 19/276 (6%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQ--------------I 781 +++G+ LG G+ KV ARN T Q A+KV K G ++ I Sbjct: 19 WKLGETLGLGSTGKVQLARNGSTGQEAAVKVISKAVFNTGNVSGTSIVGSTTPDALPYGI 78 Query: 782 KREISVMKLVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNK-VQRGRLKEDAARKYFQ 958 +REI +MKL+ HPN++++Y+V T T +Y VLE+ + GELFN V+RG L E A ++F+ Sbjct: 79 EREIIIMKLLNHPNVLRLYDVWETNTDLYLVLEYAEKGELFNLLVERGPLPEHEAIRFFR 138 Query: 959 QLICAVDFCHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPA 1138 Q+I V +CH+ G+ HRDLKPENLLLD N+K++DFG++ + + LL TSCG+P Sbjct: 139 QIIIGVSYCHALGIVHRDLKPENLLLDHKYNIKIADFGMAALETEGK---LLETSCGSPH 195 Query: 1139 YVAPEVINRKGYDGAKADIWSCGVILFVLMAGYLPF--QDKNLMNMYKKIGKAEFKCPS- 1309 Y APE+++ Y G +D+WSCGVILF L+ G LPF +D N+ + K+ K EF+ PS Sbjct: 196 YAAPEIVSGIPYQGFASDVWSCGVILFALLTGRLPFDEEDGNIRTLLLKVQKGEFEMPSD 255 Query: 1310 -WFSSDXXXXXXXXXDPNPSTRISIEKIMEHPWFRK 1414 S + +P RI I++HP +K Sbjct: 256 DEISREAQDLIRKILTVDPERRIKTRDILKHPLLQK 291
>P57059:SN1L1_HUMAN Serine/threonine-protein kinase SNF1-like kinase 1 - Homo sapiens| (Human) Length = 783 Score = 205 bits (521), Expect = 7e-52 Identities = 110/273 (40%), Positives = 165/273 (60%), Gaps = 2/273 (0%) Frame = +2 Query: 599 PAIMGE-QKGNILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTD 775 PA G+ Q+ + + Y++ + LG+G FA V AR+ T VAIK+ DK ++ L + Sbjct: 11 PAGQGQGQQKPLRVGFYDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRLDSSNL-E 69 Query: 776 QIKREISVMKLVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKV-QRGRLKEDAARKY 952 +I RE+ +MKL+ HP+I+++Y+VM TK +Y V E K GE+F+ + G L E+ ARK Sbjct: 70 KIYREVQLMKLLNHPHIIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKK 129 Query: 953 FQQLICAVDFCHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGT 1132 F Q++ AV++CH + HRDLK ENLLLD N ++K++DFG + L T CG+ Sbjct: 130 FWQILSAVEYCHDHHIVHRDLKTENLLLDGNMDIKLADFGFGNFYKSGEP---LSTWCGS 186 Query: 1133 PAYVAPEVINRKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSW 1312 P Y APEV K Y+G + DIWS GV+L+VL+ G LPF NL + +++ + F+ P + Sbjct: 187 PPYAAPEVFEGKEYEGPQLDIWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPFF 246 Query: 1313 FSSDXXXXXXXXXDPNPSTRISIEKIMEHPWFR 1411 S D +P+ RI+I +I +H W R Sbjct: 247 MSQDCESLIRRMLVVDPARRITIAQIRQHRWMR 279
>Q9R1U5:SN1L1_RAT Serine/threonine-protein kinase SNF1-like kinase 1 - Rattus| norvegicus (Rat) Length = 776 Score = 204 bits (520), Expect = 9e-52 Identities = 106/257 (41%), Positives = 158/257 (61%), Gaps = 1/257 (0%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 Y++ + LG+G FA V AR+ T VAIK+ DK ++ L ++I RE+ +MKL+ HPN Sbjct: 27 YDVERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRLDSSNL-EKIYREVQLMKLLNHPN 85 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNKV-QRGRLKEDAARKYFQQLICAVDFCHSRGV 1000 I+++Y+VM TK +Y V E K GE+F+ + G L E+ ARK F Q++ AV++CH+ + Sbjct: 86 IIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILSAVEYCHNHHI 145 Query: 1001 YHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKGYDG 1180 HRDLK ENLLLD N ++K++DFG + L T CG+P Y APEV K Y+G Sbjct: 146 VHRDLKTENLLLDGNMDIKLADFGFGNFYKPGEP---LSTWCGSPPYAAPEVFEGKEYEG 202 Query: 1181 AKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXXXDPN 1360 + DIWS GV+L+VL+ G LPF NL + +++ + F+ P + S D + Sbjct: 203 PQLDIWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPFFMSQDCETLIRRMLVVD 262 Query: 1361 PSTRISIEKIMEHPWFR 1411 P+ RI+I +I +H W + Sbjct: 263 PAKRITIAQIRQHRWMQ 279
>P45894:AAPK1_CAEEL 5'-AMP-activated protein kinase catalytic subunit alpha-1 -| Caenorhabditis elegans Length = 589 Score = 203 bits (516), Expect = 3e-51 Identities = 100/265 (37%), Positives = 160/265 (60%), Gaps = 2/265 (0%) Frame = +2 Query: 623 GNILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVM 802 G++ + + + + +G+G F V +I+T VAIK+ ++ ++ G ++ + EI + Sbjct: 17 GHLKIGNFVIKETIGKGAFGAVKRGTHIQTGYDVAIKILNRGRMKGLGTVNKTRNEIDNL 76 Query: 803 KLVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQR-GRLKEDAARKYFQQLICAVD 979 + + HP+I +++ V++T + I+ V+E V GGELF+ + R G L +R+YFQQ+I V Sbjct: 77 QKLTHPHITRLFRVISTPSDIFLVMELVSGGELFSYITRKGALPIRESRRYFQQIISGVS 136 Query: 980 FCHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDG-LLHTSCGTPAYVAPEV 1156 +CH+ + HRDLKPENLLLD N N+K++DFGLS DG LL T+CG+P Y APE+ Sbjct: 137 YCHNHMIVHRDLKPENLLLDANKNIKIADFGLSNYMT----DGDLLSTACGSPNYAAPEL 192 Query: 1157 INRKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXX 1336 I+ K Y G + D+WSCGVIL+ ++ G LPF D+N+ ++ KI + P Sbjct: 193 ISNKLYVGPEVDLWSCGVILYAMLCGTLPFDDQNVPTLFAKIKSGRYTVPYSMEKQAADL 252 Query: 1337 XXXXXDPNPSTRISIEKIMEHPWFR 1411 +P R +++I+ H WFR Sbjct: 253 ISTMLQVDPVKRADVKRIVNHSWFR 277
>Q5REX1:SN1L2_PONPY Serine/threonine-protein kinase SNF1-like kinase 2 - Pongo pygmaeus| (Orangutan) Length = 925 Score = 201 bits (512), Expect = 8e-51 Identities = 106/264 (40%), Positives = 160/264 (60%), Gaps = 1/264 (0%) Frame = +2 Query: 617 QKGNILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREIS 796 Q+G + + Y++ LG+G FA V R+ T VAIK+ DK ++ L ++I RE+ Sbjct: 11 QRGPVRVGFYDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDAVNL-EKIYREVQ 69 Query: 797 VMKLVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKV-QRGRLKEDAARKYFQQLICA 973 +MK++ HP+I+++Y+VM TK+ +Y V E+ K GE+F+ + GRL E AR+ F Q++ A Sbjct: 70 IMKMLDHPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSA 129 Query: 974 VDFCHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPE 1153 VD+CH R + HRDLK ENLLLD N N+K++DF + L L T G+P Y APE Sbjct: 130 VDYCHGRKIVHRDLKAENLLLDNNMNIKIADFSFGNFFKSGEL---LATWRGSPPYAAPE 186 Query: 1154 VINRKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXX 1333 V + Y+G + DIWS GV+L+VL+ G LPF L + +++ + F+ P + S D Sbjct: 187 VFEGQQYEGPQLDIWSMGVVLYVLVCGALPFDGPTLPILRQRVLEGRFRIPYFMSEDCEH 246 Query: 1334 XXXXXXDPNPSTRISIEKIMEHPW 1405 +PS R++I +I EH W Sbjct: 247 LIRRMLVLDPSKRLTIAQIKEHKW 270
>P34244:HSL1_YEAST Probable serine/threonine-protein kinase HSL1 - Saccharomyces| cerevisiae (Baker's yeast) Length = 1518 Score = 201 bits (511), Expect = 1e-50 Identities = 107/304 (35%), Positives = 174/304 (57%), Gaps = 37/304 (12%) Frame = +2 Query: 614 EQKGNILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVL-----KGGLTDQ 778 ++K + +++GK LG+G+ +V A+N+ET Q AIK+ K+K G + + Sbjct: 71 KRKSRDTVGPWKLGKTLGKGSSGRVRLAKNMETGQLAAIKIVPKKKAFVHCSNNGTVPNS 130 Query: 779 ------------------------------IKREISVMKLVKHPNIVQMYEVMATKTKIY 868 I+REI +MKL+ H N++ ++EV K+++Y Sbjct: 131 YSSSMVTSNVSSPSIASREHSNHSQTNPYGIEREIVIMKLISHTNVMALFEVWENKSELY 190 Query: 869 FVLEHVKGGELFNK-VQRGRLKEDAARKYFQQLICAVDFCHSRGVYHRDLKPENLLLDE- 1042 VLE+V GGELF+ V +G+L E A YF+Q++ V +CHS + HRDLKPENLLLD+ Sbjct: 191 LVLEYVDGGELFDYLVSKGKLPEREAIHYFKQIVEGVSYCHSFNICHRDLKPENLLLDKK 250 Query: 1043 NSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKGYDGAKADIWSCGVILFV 1222 N +K++DFG++ + +L L TSCG+P Y +PE++ + Y G +D+WSCG++LF Sbjct: 251 NRRIKIADFGMAALELPNKL---LKTSCGSPHYASPEIVMGRPYHGGPSDVWSCGIVLFA 307 Query: 1223 LMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXXXDPNPSTRISIEKIMEHP 1402 L+ G+LPF D N+ + K+ +++ PS SS+ +P RI+ ++I++HP Sbjct: 308 LLTGHLPFNDDNIKKLLLKVQSGKYQMPSNLSSEARDLISKILVIDPEKRITTQEILKHP 367 Query: 1403 WFRK 1414 +K Sbjct: 368 LIKK 371
>Q60670:SN1L1_MOUSE Serine/threonine-protein kinase SNF1-like kinase 1 - Mus musculus| (Mouse) Length = 779 Score = 201 bits (510), Expect = 1e-50 Identities = 108/273 (39%), Positives = 164/273 (60%), Gaps = 1/273 (0%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 Y++ + LG+G FA V AR+ T VAIK+ DK ++ L ++I RE+ +MKL+ HPN Sbjct: 27 YDVERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRLDSSNL-EKIYREVQLMKLLNHPN 85 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNKV-QRGRLKEDAARKYFQQLICAVDFCHSRGV 1000 I+++Y+VM TK +Y V E K GE+F+ + G L E+ AR+ F Q++ AV++CH+ + Sbjct: 86 IIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARQKFWQILSAVEYCHNHHI 145 Query: 1001 YHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKGYDG 1180 HRDLK ENLLLD N ++K++DFG + L T G+P Y APEV K Y+G Sbjct: 146 VHRDLKTENLLLDSNMDIKLADFGFGNFYKPGEP---LSTCVGSPPYAAPEVFEGKEYEG 202 Query: 1181 AKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXXXDPN 1360 + D+WS GV+L+VL+ G LPF NL + +++ + F+ P + S D + Sbjct: 203 PQLDVWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPFFMSQDCETLIRRMLVVD 262 Query: 1361 PSTRISIEKIMEHPWFRKGLDAKLLRYNLQAKD 1459 P+ RI+I +I +H W + D LL+ + A D Sbjct: 263 PAKRITIAQIRQHRWMQ--ADPTLLQQDDPAFD 293
>P27448:MARK3_HUMAN MAP/microtubule affinity-regulating kinase 3 - Homo sapiens (Human)| Length = 776 Score = 200 bits (508), Expect = 2e-50 Identities = 106/282 (37%), Positives = 165/282 (58%), Gaps = 24/282 (8%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 Y + K +G+G FAKV AR+I T + VAIK+ DK ++ L ++ RE+ +MK++ HPN Sbjct: 56 YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSL-QKLFREVRIMKILNHPN 114 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNK-VQRGRLKEDAARKYFQQ------------- 961 IV+++EV+ T+ +Y ++E+ GGE+F+ V GR+KE AR F+Q Sbjct: 115 IVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQGCQAGQTIKVQVS 174 Query: 962 ----------LICAVDFCHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGL 1111 ++ AV +CH + + HRDLK ENLLLD + N+K++DFG S + G Sbjct: 175 FDLLSLMFTFIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFT---VGGK 231 Query: 1112 LHTSCGTPAYVAPEVINRKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKA 1291 L T CG+P Y APE+ K YDG + D+WS GVIL+ L++G LPF +NL + +++ + Sbjct: 232 LDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRG 291 Query: 1292 EFKCPSWFSSDXXXXXXXXXDPNPSTRISIEKIMEHPWFRKG 1417 +++ P + S+D NP R ++E+IM+ W G Sbjct: 292 KYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQIMKDRWINAG 333
>O60285:NUAK1_HUMAN NUAK family SNF1-like kinase 1 - Homo sapiens (Human)| Length = 661 Score = 199 bits (505), Expect = 5e-50 Identities = 110/302 (36%), Positives = 166/302 (54%), Gaps = 5/302 (1%) Frame = +2 Query: 527 RPQVPLQAPGIAAAFFCVRLPACLP----AIMGEQKGNILMHKYEMGKMLGQGTFAKVYH 694 RP + L APG A P + + L H+YE+ + LG+GT+ KV Sbjct: 12 RPDLGLGAPGSPREAVAGATAALEPRKPHGVKRHHHKHNLKHRYELQETLGKGTYGKVKR 71 Query: 695 ARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPNIVQMYEVMATKTKIYFV 874 A + + VAIK K+K+ I+REI +M + HP+I+ +YEV K KI + Sbjct: 72 ATERFSGRVVAIKSIRKDKIKDEQDMVHIRREIEIMSSLNHPHIISIYEVFENKDKIVII 131 Query: 875 LEHVKGGELFNKV-QRGRLKEDAARKYFQQLICAVDFCHSRGVYHRDLKPENLLLDENSN 1051 +E+ GEL++ + +R RL E R +F+Q++ AV +CH GV HRDLK EN+LLD+N N Sbjct: 132 MEYASKGELYDYISERRRLSERETRHFFRQIVSAVHYCHKNGVVHRDLKLENILLDDNCN 191 Query: 1052 LKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKGYDGAKADIWSCGVILFVLMA 1231 +K++DFGLS + + D L T CG+P Y +PE++N + Y G + D W+ GV+L+ L+ Sbjct: 192 IKIADFGLSNLYQ---KDKFLQTFCGSPLYASPEIVNGRPYRGPEVDSWALGVLLYTLVY 248 Query: 1232 GYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXXXDPNPSTRISIEKIMEHPWFR 1411 G +PF + N+ ++I E++ P+ SD NP R +IE I H W Sbjct: 249 GTMPFDGFDHKNLIRQISSGEYREPTQ-PSDARGLIRWMLMVNPDRRATIEDIANHWWVN 307 Query: 1412 KG 1417 G Sbjct: 308 WG 309
>Q6ZI44:SAPK6_ORYSJ Serine/threonine-protein kinase SAPK6 - Oryza sativa subsp. japonica| (Rice) Length = 365 Score = 197 bits (500), Expect = 2e-49 Identities = 115/279 (41%), Positives = 160/279 (57%), Gaps = 13/279 (4%) Frame = +2 Query: 635 MHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVK 814 M KYE+ K +G G F RN ET + VA+K + LK + + + REI + ++ Sbjct: 1 MEKYELLKDIGSGNFGVARLMRNRETKELVAMKYIPRG--LK--IDENVAREIINHRSLR 56 Query: 815 HPNIVQMYEVMATKTKIYFVLEHVKGGELFNKV-QRGRLKEDAARKYFQQLICAVDFCHS 991 HPNI++ EV+ T T + V+E+ GGELF+++ GR ED +R +FQQLIC V +CH Sbjct: 57 HPNIIRFKEVVLTPTHLAIVMEYAAGGELFDRICSAGRFSEDESRYFFQQLICGVSYCHF 116 Query: 992 RGVYHRDLKPENLLLDENS--NLKVSDFGLSTISECRRLDGLLHT----SCGTPAYVAPE 1153 + HRDLK EN LLD + LK+ DFG S S LLH+ + GTPAY+APE Sbjct: 117 MQICHRDLKLENTLLDGSPAPRLKICDFGYSKSS-------LLHSKPKSTVGTPAYIAPE 169 Query: 1154 VINRKGYDGAKADIWSCGVILFVLMAGYLPFQD----KNLMNMYKKIGKAEFKCPSW--F 1315 V++R+ YDG AD+WSCGV L+V++ G PF+D KN +I ++K P + Sbjct: 170 VLSRREYDGKMADVWSCGVTLYVMLVGAYPFEDPDDPKNFRKTIGRIVSIQYKIPEYVHI 229 Query: 1316 SSDXXXXXXXXXDPNPSTRISIEKIMEHPWFRKGLDAKL 1432 S D NP+ RI+I +I HPWF K L +L Sbjct: 230 SQDCRQLLSRIFVANPAKRITIREIRNHPWFMKNLPREL 268
>Q5N942:SAPK4_ORYSJ Serine/threonine-protein kinase SAPK4 - Oryza sativa subsp. japonica| (Rice) Length = 360 Score = 197 bits (500), Expect = 2e-49 Identities = 110/275 (40%), Positives = 160/275 (58%), Gaps = 9/275 (3%) Frame = +2 Query: 635 MHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVK 814 M KYE + +G G F RN ET + VA+K ++ + + + REI + ++ Sbjct: 1 MEKYEAVRDIGSGNFGVARLMRNRETRELVAVKCIERGH----RIDENVYREIINHRSLR 56 Query: 815 HPNIVQMYEVMATKTKIYFVLEHVKGGELFNKV-QRGRLKEDAARKYFQQLICAVDFCHS 991 HPNI++ EV+ T T + V+E GGELF+++ RGR ED AR +FQQLIC V +CH Sbjct: 57 HPNIIRFKEVILTPTHLMIVMEFAAGGELFDRICDRGRFSEDEARYFFQQLICGVSYCHH 116 Query: 992 RGVYHRDLKPENLLLDENS--NLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINR 1165 + HRDLK EN+LLD + LK+ DFG S S L ++ GTPAY+APEV++R Sbjct: 117 MQICHRDLKLENVLLDGSPAPRLKICDFGYSKSSV---LHSRPKSAVGTPAYIAPEVLSR 173 Query: 1166 KGYDGAKADIWSCGVILFVLMAGYLPFQD----KNLMNMYKKIGKAEFKCPSW--FSSDX 1327 + YDG AD+WSCGV L+V++ G PF+D KN+ ++I ++K P + S++ Sbjct: 174 REYDGKLADVWSCGVTLYVMLVGAYPFEDQDDPKNIRKTIQRIMSVQYKIPDYVHISAEC 233 Query: 1328 XXXXXXXXDPNPSTRISIEKIMEHPWFRKGLDAKL 1432 NP RI++++I HPWF K L +L Sbjct: 234 KQLIARIFVNNPLRRITMKEIKSHPWFLKNLPREL 268
>Q641K5:NUAK1_MOUSE NUAK family SNF1-like kinase 1 - Mus musculus (Mouse)| Length = 658 Score = 197 bits (500), Expect = 2e-49 Identities = 102/263 (38%), Positives = 155/263 (58%), Gaps = 1/263 (0%) Frame = +2 Query: 632 LMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLV 811 L H+YE+ + LG+GT+ KV A + + VAIK K+K+ I+REI +M + Sbjct: 52 LKHRYELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDELDMVHIRREIEIMSSL 111 Query: 812 KHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKV-QRGRLKEDAARKYFQQLICAVDFCH 988 HP+I+ +YEV K KI ++E+ GEL++ + +R RL E R +F+Q++ AV +CH Sbjct: 112 NHPHIISIYEVFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHYCH 171 Query: 989 SRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRK 1168 GV HRDLK EN+LLD+N N+K++DFGLS + + D L T CG+P Y +PE++N + Sbjct: 172 KNGVVHRDLKLENILLDDNCNIKIADFGLSNLYQ---KDKFLQTFCGSPLYASPEIVNGR 228 Query: 1169 GYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXX 1348 Y G + D W+ GV+L+ L+ G +PF + N+ ++I E++ P+ SD Sbjct: 229 PYRGPEVDSWALGVLLYTLIYGTMPFDGFDHKNLIRQISSGEYREPTQ-PSDARGLIRWM 287 Query: 1349 XDPNPSTRISIEKIMEHPWFRKG 1417 NP R +IE I H W G Sbjct: 288 LMVNPDRRATIEDIANHWWVNWG 310
>Q9NRH2:SNRK_HUMAN SNF-related serine/threonine-protein kinase - Homo sapiens (Human)| Length = 765 Score = 196 bits (498), Expect = 3e-49 Identities = 110/271 (40%), Positives = 159/271 (58%), Gaps = 3/271 (1%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 Y++ K LG+G FA V AR++ T + VA+KV DK K L T + +E+ MKLV+HPN Sbjct: 16 YDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTK-LDTLATGHLFQEVRCMKLVQHPN 74 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNKVQRGR--LKEDAARKYFQQLICAVDFCHSRG 997 IV++YEV+ T+TK+Y +LE GG++F+ + + L ED A+KYF Q++ A+ +CH Sbjct: 75 IVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISYCHKLH 134 Query: 998 VYHRDLKPENLLLDENSNL-KVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKGY 1174 V HRDLKPEN++ E L K++DFG S + + L TSCG+ AY APE++ Y Sbjct: 135 VVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKK---LTTSCGSLAYSAPEILLGDEY 191 Query: 1175 DGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXXXD 1354 D DIWS GVILF+L+ G PFQ+ N I ++ PS S + Sbjct: 192 DAPAVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMDCKYTVPSHVSKECKDLITRMLQ 251 Query: 1355 PNPSTRISIEKIMEHPWFRKGLDAKLLRYNL 1447 +P R S+E+I HPW + + +YN+ Sbjct: 252 RDPKRRASLEEIENHPWLQGVDPSPATKYNI 282
>Q7XQP4:SAPK7_ORYSJ Serine/threonine-protein kinase SAPK7 - Oryza sativa subsp. japonica| (Rice) Length = 359 Score = 196 bits (498), Expect = 3e-49 Identities = 115/279 (41%), Positives = 160/279 (57%), Gaps = 13/279 (4%) Frame = +2 Query: 635 MHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVK 814 M +YE+ K +G G F RN ET + VA+K + LK + + + REI + ++ Sbjct: 1 MERYELLKDIGAGNFGVARLMRNKETKELVAMKYIPRG--LK--IDENVAREIINHRSLR 56 Query: 815 HPNIVQMYEVMATKTKIYFVLEHVKGGELFNKV-QRGRLKEDAARKYFQQLICAVDFCHS 991 HPNI++ EV+ T T + V+E+ GGELF+++ GR ED AR +FQQLIC V +CH Sbjct: 57 HPNIIRFKEVVVTPTHLAIVMEYAAGGELFDRICNAGRFSEDEARYFFQQLICGVSYCHF 116 Query: 992 RGVYHRDLKPENLLLDENS--NLKVSDFGLSTISECRRLDGLLHT----SCGTPAYVAPE 1153 + HRDLK EN LLD + LK+ DFG S S LLH+ + GTPAY+APE Sbjct: 117 MQICHRDLKLENTLLDGSPAPRLKICDFGYSKSS-------LLHSKPKSTVGTPAYIAPE 169 Query: 1154 VINRKGYDGAKADIWSCGVILFVLMAGYLPFQD----KNLMNMYKKIGKAEFKCPSW--F 1315 V++R+ YDG AD+WSCGV L+V++ G PF+D KN +I ++K P + Sbjct: 170 VLSRREYDGKTADVWSCGVTLYVMLVGAYPFEDPDDPKNFRKTIGRIMSIQYKIPEYVHV 229 Query: 1316 SSDXXXXXXXXXDPNPSTRISIEKIMEHPWFRKGLDAKL 1432 S D NP+ RI+I +I HPWF K L +L Sbjct: 230 SQDCRQLLSRIFVANPAKRITIREIRNHPWFLKNLPREL 268
>O13945:PPK9_SCHPO Protein kinase domain-containing protein ppk9 - Schizosaccharomyces| pombe (Fission yeast) Length = 532 Score = 194 bits (494), Expect = 1e-48 Identities = 97/278 (34%), Positives = 162/278 (58%), Gaps = 1/278 (0%) Frame = +2 Query: 578 VRLPACLPAIMGEQKGNILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVL 757 ++ P+ A + GN + + +G+ LGQG AKV ++ +T++ VA+K+ +++ Sbjct: 1 MQTPSSASAESEKDSGNTYVGPWLLGRTLGQGNLAKVKLGKHFQTNEKVALKMVYNDELE 60 Query: 758 KGGLTDQIKREISVMKLVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQRGRLKED 937 +++RE+++++ + HPNI+ +Y+V LE++ V+ RL E Sbjct: 61 DKDTWKRLQREVTILRQLHHPNIITLYQVFRVPKYTVLALEYMDTDLHSMVVKHNRLDEC 120 Query: 938 AARKYFQQLICAVDFCHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDG-LL 1114 RK F+Q++ A+D+CH V HRDLK EN+LL+++ +K++DFGLS LDG L Sbjct: 121 TTRKIFRQIVHAIDYCHLHRVAHRDLKLENILLNKDLVVKLTDFGLSNFM----LDGSFL 176 Query: 1115 HTSCGTPAYVAPEVINRKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAE 1294 TSCGTP Y APEVI + YDG D+W CG++L++++ G PF+D + N+ ++ K Sbjct: 177 STSCGTPHYAAPEVIQGRYYDGCDVDVWGCGILLYLMLVGEFPFEDVTISNVLSRVCKGI 236 Query: 1295 FKCPSWFSSDXXXXXXXXXDPNPSTRISIEKIMEHPWF 1408 + PS+ SS P++RI + +IM+HPWF Sbjct: 237 YTIPSFVSSSASDLIRQMLMVLPTSRIKVAEIMQHPWF 274
>P25389:KCC4_YEAST Probable serine/threonine-protein kinase KCC4 - Saccharomyces| cerevisiae (Baker's yeast) Length = 1037 Score = 193 bits (491), Expect = 2e-48 Identities = 105/270 (38%), Positives = 156/270 (57%), Gaps = 13/270 (4%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGG--------LTDQIKREISV 799 +++G+ LG G+ KV A++ T A+KV K G L I+REI + Sbjct: 21 WKLGETLGFGSTGKVQLAQHERTGHRTAVKVISKSIFNNNGNHSNDDSVLPYNIEREIVI 80 Query: 800 MKLVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNK-VQRGRLKEDAARKYFQQLICAV 976 MKL+ HPN++ +Y+V T +Y +LE+ + GELFN V G L E A F+Q+I + Sbjct: 81 MKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPEREAINCFRQIIIGI 140 Query: 977 DFCHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEV 1156 +CH+ G+ HRDLKPENLLLD N+K++DFG++ + LL TSCG+P Y APE+ Sbjct: 141 SYCHALGIVHRDLKPENLLLDSFYNIKIADFGMAALQTDA---DLLETSCGSPHYAAPEI 197 Query: 1157 INRKGYDGAKADIWSCGVILFVLMAGYLPFQDK--NLMNMYKKIGKAEFKCP--SWFSSD 1324 ++ Y+G +D+WSCGVILF L+ G LPF ++ N+ ++ K+ K +F+ P + S D Sbjct: 198 VSGLPYEGFASDVWSCGVILFALLTGRLPFDEENGNVRDLLLKVQKGQFEMPNDTEISRD 257 Query: 1325 XXXXXXXXXDPNPSTRISIEKIMEHPWFRK 1414 +P RI I I+ HP +K Sbjct: 258 AQDLIGKILVVDPRQRIKIRDILSHPLLKK 287
>Q63553:SNRK_RAT SNF-related serine/threonine-protein kinase - Rattus norvegicus (Rat)| Length = 746 Score = 193 bits (490), Expect = 3e-48 Identities = 109/271 (40%), Positives = 158/271 (58%), Gaps = 3/271 (1%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 Y++ K LG+G FA V AR++ T + VA+KV DK K L T + +E+ MKLV+HPN Sbjct: 16 YDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTK-LDTLATGHLFQEVRCMKLVQHPN 74 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNKVQRGR--LKEDAARKYFQQLICAVDFCHSRG 997 IV++YEV+ T+TK+Y +LE GG++F+ + + L ED A+KYF Q++ A+ +CH Sbjct: 75 IVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISYCHKLH 134 Query: 998 VYHRDLKPENLLLDENSNL-KVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKGY 1174 V HRDLKPEN++ E L K++DFG S + + L TSCG+ AY APE++ Y Sbjct: 135 VVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKK---LTTSCGSLAYSAPEILLGDEY 191 Query: 1175 DGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXXXD 1354 D DIWS GVILF+L+ G PFQ+ N I ++ P S+ Sbjct: 192 DAPAVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMDCKYTVPPRVSAGCRDLITRMLQ 251 Query: 1355 PNPSTRISIEKIMEHPWFRKGLDAKLLRYNL 1447 +P R S+E+I HPW + + +YN+ Sbjct: 252 RDPKRRASLEEIESHPWLQGVDPSPATKYNI 282
>Q8VDU5:SNRK_MOUSE SNF-related serine/threonine-protein kinase - Mus musculus (Mouse)| Length = 748 Score = 193 bits (490), Expect = 3e-48 Identities = 109/271 (40%), Positives = 158/271 (58%), Gaps = 3/271 (1%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 Y++ K LG+G FA V AR++ T + VA+KV DK K L T + +E+ MKLV+HPN Sbjct: 16 YDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTK-LDTLATGHLFQEVRCMKLVQHPN 74 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNKVQRGR--LKEDAARKYFQQLICAVDFCHSRG 997 IV++YEV+ T+TK+Y +LE GG++F+ + + L ED A+KYF Q++ A+ +CH Sbjct: 75 IVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISYCHKLH 134 Query: 998 VYHRDLKPENLLLDENSNL-KVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKGY 1174 V HRDLKPEN++ E L K++DFG S + + L TSCG+ AY APE++ Y Sbjct: 135 VVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKK---LTTSCGSLAYSAPEILLGDEY 191 Query: 1175 DGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXXXD 1354 D DIWS GVILF+L+ G PFQ+ N I ++ P S+ Sbjct: 192 DAPAVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMDCKYTVPPRVSAGCRDLITRMLQ 251 Query: 1355 PNPSTRISIEKIMEHPWFRKGLDAKLLRYNL 1447 +P R S+E+I HPW + + +YN+ Sbjct: 252 RDPKRRASLEEIESHPWLQGVDPSPATKYNI 282
>P87050:CDR2_SCHPO Mitosis inducer protein kinase cdr2 - Schizosaccharomyces pombe| (Fission yeast) Length = 775 Score = 193 bits (490), Expect = 3e-48 Identities = 92/255 (36%), Positives = 158/255 (61%), Gaps = 1/255 (0%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 +E+G LG G A++ ET Q +K L +I+ E+ +++L++HPN Sbjct: 10 WELGLSLGSGGPNSSRLAKHRETGQLAVVKPIVGWSELTSSQQARIEGELVLLRLIEHPN 69 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFN-KVQRGRLKEDAARKYFQQLICAVDFCHSRGV 1000 ++Q+ +V++ + +++ V+E++ GGELF+ +++G E K+ Q++C +++CH + Sbjct: 70 VLQLIDVISAQEQLFVVVEYMPGGELFDCMLRKGSFTEQDTAKFLWQILCGLEYCHKLHI 129 Query: 1001 YHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKGYDG 1180 HRDLKPENL LD + ++K+ +FG+++I + +L L TSCG+P Y +PE+I + YDG Sbjct: 130 CHRDLKPENLYLDAHGSIKIGEFGMASIQQPGKL---LQTSCGSPHYASPEIIMGRSYDG 186 Query: 1181 AKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXXXDPN 1360 +DIWSCG+I F L+ G LPF D N+ ++ K+ + +F+ PS S D + Sbjct: 187 CASDIWSCGIIFFALLTGKLPFDDDNIRSLLLKVCQGQFEMPSNISPQAQHLLYRMLDVD 246 Query: 1361 PSTRISIEKIMEHPW 1405 STRI++E+I EHP+ Sbjct: 247 SSTRITMEQIREHPF 261
>P43292:ASK2_ARATH Serine/threonine-protein kinase ASK2 - Arabidopsis thaliana| (Mouse-ear cress) Length = 353 Score = 192 bits (489), Expect = 4e-48 Identities = 110/280 (39%), Positives = 163/280 (58%), Gaps = 13/280 (4%) Frame = +2 Query: 635 MHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVK 814 M KY++ K LG G F R+ +T + VA+K ++ + + + + REI + +K Sbjct: 1 MDKYDVVKDLGAGNFGVARLLRHKDTKELVAMKYIERGRKID----ENVAREIINHRSLK 56 Query: 815 HPNIVQMYEVMATKTKIYFVLEHVKGGELFNKV-QRGRLKEDAARKYFQQLICAVDFCHS 991 HPNI++ EV+ T T + V+E+ GGELF+++ GR E AR +FQQLIC VD+CHS Sbjct: 57 HPNIIRFKEVILTPTHLAIVMEYASGGELFDRICTAGRFSEAEARYFFQQLICGVDYCHS 116 Query: 992 RGVYHRDLKPENLLLDENSN--LKVSDFGLSTISECRRLDGLLHT----SCGTPAYVAPE 1153 + HRDLK EN LLD + LK+ DFG S S +LH+ + GTPAY+APE Sbjct: 117 LQICHRDLKLENTLLDGSPAPLLKICDFGYSKSS-------ILHSRPKSTVGTPAYIAPE 169 Query: 1154 VINRKGYDGAKADIWSCGVILFVLMAGYLPFQD----KNLMNMYKKIGKAEFKCPSW--F 1315 V++R+ YDG AD+WSCGV L+V++ G PF+D KN ++I ++K P + Sbjct: 170 VLSRREYDGKHADVWSCGVTLYVMLVGAYPFEDPNDPKNFRKTIQRIMAVQYKIPDYVHI 229 Query: 1316 SSDXXXXXXXXXDPNPSTRISIEKIMEHPWFRKGLDAKLL 1435 S + N + RI++++I HPW+ K L +LL Sbjct: 230 SQECKHLLSRIFVTNSAKRITLKEIKNHPWYLKNLPKELL 269
>Q75V57:SAPK9_ORYSJ Serine/threonine-protein kinase SAPK9 - Oryza sativa subsp. japonica| (Rice) Length = 361 Score = 190 bits (483), Expect = 2e-47 Identities = 112/281 (39%), Positives = 161/281 (57%), Gaps = 13/281 (4%) Frame = +2 Query: 632 LMH---KYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDK-EKVLKGGLTDQIKREISV 799 +MH +YE+ K +G G F RN + VA+K D+ EK+ + ++REI Sbjct: 15 IMHDGDRYELVKEIGSGNFGVARLMRNRASGDLVAVKYIDRGEKI-----DENVQREIIN 69 Query: 800 MKLVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKV-QRGRLKEDAARKYFQQLICAV 976 + ++HPNI++ EV+ T T + V+E+ GGELF ++ GR ED AR +FQQLI V Sbjct: 70 HRSLRHPNIIRFKEVILTPTHLAIVMEYASGGELFERICSAGRFSEDEARFFFQQLISGV 129 Query: 977 DFCHSRGVYHRDLKPENLLLDENS--NLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAP 1150 +CHS V HRDLK EN LLD ++ LK+ DFG S S L ++ GTPAY+AP Sbjct: 130 SYCHSMQVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSV---LHSQPKSTVGTPAYIAP 186 Query: 1151 EVINRKGYDGAKADIWSCGVILFVLMAGYLPFQD----KNLMNMYKKIGKAEFKCPSW-- 1312 EV+ +K YDG AD+WSCGV L+V++ G PF+D KN +KI ++ P + Sbjct: 187 EVLLKKEYDGKIADVWSCGVTLYVMLVGAYPFEDPEDPKNFRKTIQKILGVQYSIPDYVH 246 Query: 1313 FSSDXXXXXXXXXDPNPSTRISIEKIMEHPWFRKGLDAKLL 1435 S + NP++RI++ +I HPWF K + A L+ Sbjct: 247 ISPECRDLITRIFVGNPASRITMPEIKNHPWFMKNIPADLM 287
>Q7XKA8:SAPK5_ORYSJ Serine/threonine-protein kinase SAPK5 - Oryza sativa subsp. japonica| (Rice) Length = 370 Score = 190 bits (483), Expect = 2e-47 Identities = 113/294 (38%), Positives = 162/294 (55%), Gaps = 19/294 (6%) Frame = +2 Query: 635 MHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVK 814 M KYE + +G G F RN ET + VA+K ++ + + + REI + ++ Sbjct: 1 MEKYEPVREIGAGNFGVAKLMRNKETRELVAMKFIERGN----RIDENVFREIVNHRSLR 56 Query: 815 HPNIVQMYEVMATKTKIYFVLEHVKGGELFNKV-QRGRLKEDAARKYFQQLICAVDFCHS 991 HPNI++ EV+ T + V+E+ GGELF ++ + GR ED AR +FQQL+C V +CH+ Sbjct: 57 HPNIIRFKEVVVTGRHLAIVMEYAAGGELFERICEAGRFHEDEARYFFQQLVCGVSYCHA 116 Query: 992 RGVYHRDLKPENLLLDENS--NLKVSDFGLSTISECRRLDGLLHT----SCGTPAYVAPE 1153 + HRDLK EN LLD + LK+ DFG S S LLH+ + GTPAY+APE Sbjct: 117 MQICHRDLKLENTLLDGSPAPRLKICDFGYSKSS-------LLHSRPKSTVGTPAYIAPE 169 Query: 1154 VINRKGYDGAKADIWSCGVILFVLMAGYLPFQD----KNLMNMYKKIGKAEFKCPSW--F 1315 V++R+ YDG AD+WSCGV L+V++ G PF+D KN +I ++K P + Sbjct: 170 VLSRREYDGKLADVWSCGVTLYVMLVGAYPFEDPKDPKNFRKTISRIMSVQYKIPEYVHV 229 Query: 1316 SSDXXXXXXXXXDPNPSTRISIEKIMEHPWFRKGL------DAKLLRYNLQAKD 1459 S NP RIS+ +I HPWF K L +A+ + YN + D Sbjct: 230 SQPCRHLLSRIFVANPYKRISMGEIKSHPWFLKNLPRELKEEAQAVYYNRRGAD 283
>Q75LR7:SAPK1_ORYSJ Serine/threonine-protein kinase SAPK1 - Oryza sativa subsp. japonica| (Rice) Length = 342 Score = 190 bits (482), Expect = 2e-47 Identities = 110/275 (40%), Positives = 157/275 (57%), Gaps = 9/275 (3%) Frame = +2 Query: 635 MHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVK 814 M +YE+ + +G G F R++ T+ A+K E+ LK + + ++REI + +K Sbjct: 1 MERYEVMRDIGSGNFGVAKLVRDVATNHLFAVKFI--ERGLK--IDEHVQREIMNHRSLK 56 Query: 815 HPNIVQMYEVMATKTKIYFVLEHVKGGELFNKV-QRGRLKEDAARKYFQQLICAVDFCHS 991 HPNI++ EV+ T T + V+E+ GGELF ++ GR ED AR +FQQLI V +CHS Sbjct: 57 HPNIIRFKEVVLTPTHLAIVMEYAAGGELFERICNAGRFSEDEARFFFQQLISGVSYCHS 116 Query: 992 RGVYHRDLKPENLLLDEN--SNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINR 1165 V HRDLK EN LLD + LK+ DFG S S L ++ GTPAY+APEV++R Sbjct: 117 MQVCHRDLKLENTLLDGSVTPRLKICDFGYSKSSV---LHSQPKSTVGTPAYIAPEVLSR 173 Query: 1166 KGYDGAKADIWSCGVILFVLMAGYLPFQD----KNLMNMYKKIGKAEFKCPSW--FSSDX 1327 K YDG AD+WSCGV L+V++ G PF+D +N +I ++ P + S+D Sbjct: 174 KEYDGKVADVWSCGVTLYVMLVGAYPFEDPDDPRNFRKTITRILSVQYSIPDYVRVSADC 233 Query: 1328 XXXXXXXXDPNPSTRISIEKIMEHPWFRKGLDAKL 1432 NP RI+I +I HPWF K L ++ Sbjct: 234 RHLLSRIFVGNPEQRITIPEIKNHPWFLKNLPIEM 268
>O88866:HUNK_MOUSE Hormonally up-regulated neu tumor-associated kinase - Mus musculus| (Mouse) Length = 714 Score = 190 bits (482), Expect = 2e-47 Identities = 109/293 (37%), Positives = 172/293 (58%), Gaps = 10/293 (3%) Frame = +2 Query: 584 LPACLPAIMGEQKGNILMHK----YEMG-KMLGQGTFAKVYHARNIETSQSVAIKVTDKE 748 LPA + + E+ + HK Y +G + LG+G+FAKV ++ T + VAIKV DK+ Sbjct: 37 LPAWVSGVSRERLRDFQHHKRVGNYLIGSRKLGEGSFAKVREGLHVLTGEKVAIKVIDKK 96 Query: 749 KVLKGG-LTDQIKREISVMKLVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKV-QRG 922 + K +T ++RE + ++++HPNI Q+ +++ T+ Y V+E GG L +K+ ++ Sbjct: 97 RAKKDTYVTKNLRREGQIQQMIRHPNITQLLDILETENSYYLVMELCPGGNLMHKIYEKK 156 Query: 923 RLKEDAARKYFQQLICAVDFCHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRL 1102 RL E AR+Y +QLI AV+ H GV HRDLK ENLLLDE++N+K+ DFGLS + Sbjct: 157 RLDEAEARRYIRQLISAVEHLHRAGVVHRDLKIENLLLDEDNNIKLIDFGLSNCAGILGY 216 Query: 1103 DGLLHTSCGTPAYVAPEVINRKGYDGAKADIWSCGVILFVLMAGYLPF--QDKNLMNMYK 1276 T CG+PAY APE++ RK Y G K D+WS GV ++ ++ G LPF + +L +Y+ Sbjct: 217 SDPFSTQCGSPAYAAPELLARKKY-GPKIDVWSIGVNMYAMLTGTLPFTVEPFSLRALYQ 275 Query: 1277 K-IGKAEFKCPSWFSSDXXXXXXXXXDPNPSTRISIEKIMEHPWFRKGLDAKL 1432 K + KA P+ S+ +P+P R +I++ + + W + K+ Sbjct: 276 KMVDKAMNPLPTQLSTGAVNFLRSLLEPDPVKRPNIQQALANRWLNENYTGKV 328
>Q68UT7:HUNK_PANTR Hormonally up-regulated neu tumor-associated kinase - Pan troglodytes| (Chimpanzee) Length = 714 Score = 189 bits (481), Expect = 3e-47 Identities = 108/293 (36%), Positives = 172/293 (58%), Gaps = 10/293 (3%) Frame = +2 Query: 584 LPACLPAIMGEQKGNILMHK----YEMG-KMLGQGTFAKVYHARNIETSQSVAIKVTDKE 748 LPA + + E+ + HK Y +G + LG+G+FAKV ++ T + VAIKV DK+ Sbjct: 37 LPAWVSGVPRERLRDFQHHKRVGNYLIGSRKLGEGSFAKVREGLHVLTGEKVAIKVIDKK 96 Query: 749 KVLKGG-LTDQIKREISVMKLVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKV-QRG 922 + K +T ++RE + ++++HPNI Q+ +++ T+ Y V+E GG L +K+ ++ Sbjct: 97 RAKKDTYVTKNLRREGQIQQMIRHPNITQLLDILETENSYYLVMELCPGGNLMHKIYEKK 156 Query: 923 RLKEDAARKYFQQLICAVDFCHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRL 1102 RL+E AR+Y +QLI AV+ H GV HRDLK ENLLLDE++N+K+ DFGLS + Sbjct: 157 RLEESEARRYIRQLISAVEHLHRAGVVHRDLKIENLLLDEDNNIKLIDFGLSNCAGILGY 216 Query: 1103 DGLLHTSCGTPAYVAPEVINRKGYDGAKADIWSCGVILFVLMAGYLPF--QDKNLMNMYK 1276 T CG+PAY APE++ RK Y G K D+WS GV ++ ++ G LPF + +L +Y+ Sbjct: 217 SDPFSTQCGSPAYAAPELLARKKY-GPKIDVWSIGVNMYAMLTGTLPFTVEPFSLRALYQ 275 Query: 1277 KIGKAEFK-CPSWFSSDXXXXXXXXXDPNPSTRISIEKIMEHPWFRKGLDAKL 1432 K+ E P+ S+ +P+P R +I++ + + W + K+ Sbjct: 276 KMVDKEMNPLPTQLSTGAISFLRSLLEPDPVKRPNIQQALANRWLNENYTGKV 328
>P57058:HUNK_HUMAN Hormonally up-regulated neu tumor-associated kinase - Homo sapiens| (Human) Length = 714 Score = 189 bits (481), Expect = 3e-47 Identities = 108/293 (36%), Positives = 172/293 (58%), Gaps = 10/293 (3%) Frame = +2 Query: 584 LPACLPAIMGEQKGNILMHK----YEMG-KMLGQGTFAKVYHARNIETSQSVAIKVTDKE 748 LPA + + E+ + HK Y +G + LG+G+FAKV ++ T + VAIKV DK+ Sbjct: 37 LPAWVSGVPRERLRDFQHHKRVGNYLIGSRKLGEGSFAKVREGLHVLTGEKVAIKVIDKK 96 Query: 749 KVLKGG-LTDQIKREISVMKLVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKV-QRG 922 + K +T ++RE + ++++HPNI Q+ +++ T+ Y V+E GG L +K+ ++ Sbjct: 97 RAKKDTYVTKNLRREGQIQQMIRHPNITQLLDILETENSYYLVMELCPGGNLMHKIYEKK 156 Query: 923 RLKEDAARKYFQQLICAVDFCHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRL 1102 RL+E AR+Y +QLI AV+ H GV HRDLK ENLLLDE++N+K+ DFGLS + Sbjct: 157 RLEESEARRYIRQLISAVEHLHRAGVVHRDLKIENLLLDEDNNIKLIDFGLSNCAGILGY 216 Query: 1103 DGLLHTSCGTPAYVAPEVINRKGYDGAKADIWSCGVILFVLMAGYLPF--QDKNLMNMYK 1276 T CG+PAY APE++ RK Y G K D+WS GV ++ ++ G LPF + +L +Y+ Sbjct: 217 SDPFSTQCGSPAYAAPELLARKKY-GPKIDVWSIGVNMYAMLTGTLPFTVEPFSLRALYQ 275 Query: 1277 KIGKAEFK-CPSWFSSDXXXXXXXXXDPNPSTRISIEKIMEHPWFRKGLDAKL 1432 K+ E P+ S+ +P+P R +I++ + + W + K+ Sbjct: 276 KMVDKEMNPLPTQLSTGAISFLRSLLEPDPVKRPNIQQALANRWLNENYTGKV 328
>Q75H77:SAPKA_ORYSJ Serine/threonine-protein kinase SAPK10 - Oryza sativa subsp. japonica| (Rice) Length = 362 Score = 189 bits (479), Expect = 5e-47 Identities = 111/280 (39%), Positives = 159/280 (56%), Gaps = 12/280 (4%) Frame = +2 Query: 632 LMH---KYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVM 802 +MH +YE+ + +G G F R+ Q VA+K ++ + + ++REI Sbjct: 16 IMHDGDRYELVRDIGSGNFGVARLMRSRADGQLVAVKYIERGDKID----ENVQREIINH 71 Query: 803 KLVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKV-QRGRLKEDAARKYFQQLICAVD 979 + ++HPNI++ EV+ T T + V+E+ GGELF ++ GR ED AR +FQQLI V Sbjct: 72 RSLRHPNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLISGVS 131 Query: 980 FCHSRGVYHRDLKPENLLLDENS--NLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPE 1153 +CHS V HRDLK EN LLD ++ LK+ DFG S S L ++ GTPAY+APE Sbjct: 132 YCHSMQVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSV---LHSQPKSTVGTPAYIAPE 188 Query: 1154 VINRKGYDGAKADIWSCGVILFVLMAGYLPFQD----KNLMNMYKKIGKAEFKCPSW--F 1315 V+ +K YDG AD+WSCGV L+V++ G PF+D KN ++I ++ P + Sbjct: 189 VLLKKEYDGKIADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILGVQYSIPDYVHI 248 Query: 1316 SSDXXXXXXXXXDPNPSTRISIEKIMEHPWFRKGLDAKLL 1435 S + NP+TRISI +I HPWF K L A L+ Sbjct: 249 SPECRDLIARIFVANPATRISIPEIRNHPWFLKNLPADLM 288
>Q84TC6:SAPK2_ORYSA Serine/threonine-protein kinase SAPK2 - Oryza sativa (Rice)| Length = 339 Score = 187 bits (475), Expect = 2e-46 Identities = 108/279 (38%), Positives = 156/279 (55%), Gaps = 13/279 (4%) Frame = +2 Query: 635 MHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVK 814 M +YE+ K +G G F R++ T + A+K ++ + + + ++REI + ++ Sbjct: 1 MERYEVIKDIGSGNFGVAKLVRDVRTKELFAVKFIERGQKID----ENVQREIMNHRSLR 56 Query: 815 HPNIVQMYEVMATKTKIYFVLEHVKGGELFNKV-QRGRLKEDAARKYFQQLICAVDFCHS 991 HPNIV+ EV+ T T + V+E+ GGELF ++ GR ED AR +FQQLI V +CHS Sbjct: 57 HPNIVRFKEVVLTPTHLAIVMEYAAGGELFERICSAGRFSEDEARFFFQQLISGVSYCHS 116 Query: 992 RGVYHRDLKPENLLLDEN--SNLKVSDFGLSTISECRRLDGLLHT----SCGTPAYVAPE 1153 + HRDLK EN LLD + LK+ DFG S S LLH+ + GTPAY+APE Sbjct: 117 MQICHRDLKLENTLLDGSIAPRLKICDFGYSKSS-------LLHSQPKSTVGTPAYIAPE 169 Query: 1154 VINRKGYDGAKADIWSCGVILFVLMAGYLPFQD----KNLMNMYKKIGKAEFKCPSW--F 1315 V+ RK YDG AD+WSCGV L+V++ G PF+D +N +I ++ P + Sbjct: 170 VLARKEYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPRNFRKTITRILSVQYMVPDYVRV 229 Query: 1316 SSDXXXXXXXXXDPNPSTRISIEKIMEHPWFRKGLDAKL 1432 S + NP RI+I +I HPWF K L ++ Sbjct: 230 SMECRHLLSRIFVANPEQRITIPEIKNHPWFLKNLPIEM 268
>Q01919:KIN4_YEAST Serine/threonine-protein kinase KIN4 - Saccharomyces cerevisiae| (Baker's yeast) Length = 800 Score = 187 bits (474), Expect = 2e-46 Identities = 109/287 (37%), Positives = 163/287 (56%), Gaps = 15/287 (5%) Frame = +2 Query: 596 LPAIMGEQKGNILMHKYEMGKMLGQGTFAKVY-----HARNIETSQSVAIKVTDKEKVLK 760 L I Q+ + Y +G LG+G F KV + + E + VAIK+ ++ + K Sbjct: 30 LHPIHKNQRKHATFGPYIIGSTLGEGEFGKVKLGWTKASSSNEVPKQVAIKLIRRDTIKK 89 Query: 761 GGLTD-QIKREISVMKLVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQRGR-LKE 934 + +I REI+ +K + HPNI+ + EV+ I VLE V GGE + +QR R LKE Sbjct: 90 DADKEIKIYREINALKHLTHPNIIYLEEVLQNSKYIGIVLEFVSGGEFYKYIQRKRRLKE 149 Query: 935 DAARKYFQQLICAVDFCHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLL 1114 +A + F QLI V++ H +G+ HRDLK ENLLLD++ NL ++DFG ++E + L+ Sbjct: 150 SSACRLFAQLISGVNYMHYKGLVHRDLKLENLLLDKHENLVITDFGF--VNEFFEDNELM 207 Query: 1115 HTSCGTPAYVAPE-VINRKGYDGAKADIWSCGVILFVLMAGYLPFQD-------KNLMNM 1270 TSCG+P Y APE V++ K Y+ KAD+WSCGVIL+ ++AGYLP+ D ++ + Sbjct: 208 KTSCGSPCYAAPELVVSTKAYEARKADVWSCGVILYAMLAGYLPWDDDHENPTGDDIARL 267 Query: 1271 YKKIGKAEFKCPSWFSSDXXXXXXXXXDPNPSTRISIEKIMEHPWFR 1411 YK I + K P + + PNP RI+++ I H W + Sbjct: 268 YKYITQTPLKFPEYITPIPRDLLRRILVPNPRRRINLQTIKRHVWLK 314
>Q91819:STK6L_XENLA Serine/threonine-protein kinase Eg2-like - Xenopus laevis (African| clawed frog) Length = 408 Score = 185 bits (470), Expect = 6e-46 Identities = 93/261 (35%), Positives = 152/261 (58%), Gaps = 1/261 (0%) Frame = +2 Query: 635 MHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVK 814 + +E+G+ LG+G F VY AR E+ +A+KV K ++ K G+ Q++RE+ + ++ Sbjct: 137 LEDFEIGRPLGKGKFGNVYLARERESKFILALKVLFKSQLEKAGVEHQLRREVEIQSHLR 196 Query: 815 HPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQR-GRLKEDAARKYFQQLICAVDFCHS 991 HPNI+++Y +++Y +L++ GGELF ++Q+ R + + Y +QL A+ +CHS Sbjct: 197 HPNILRLYGYFHDASRVYLILDYAPGGELFRELQKCTRFDDQRSALYIKQLAEALLYCHS 256 Query: 992 RGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKG 1171 + V HRD+KPENLLL N LK++DFG S + R T CGT Y+ PE+I + Sbjct: 257 KKVIHRDIKPENLLLGSNGELKIADFGWSVHAPSSRRT----TLCGTLDYLPPEMIEGRM 312 Query: 1172 YDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXXX 1351 +D K D+WS GV+ + + G PF+ Y++I K EF+ P + S + Sbjct: 313 HD-EKVDLWSLGVLCYEFLVGKPPFETDTHQETYRRISKVEFQYPPYVSEEAKDLVSKLL 371 Query: 1352 DPNPSTRISIEKIMEHPWFRK 1414 NP+ R+ ++ ++EHPW K Sbjct: 372 KHNPNHRLPLKGVLEHPWIVK 392
>Q66HE5:NUAK2_RAT NUAK family SNF1-like kinase 2 - Rattus norvegicus (Rat)| Length = 630 Score = 184 bits (468), Expect = 1e-45 Identities = 97/268 (36%), Positives = 155/268 (57%), Gaps = 1/268 (0%) Frame = +2 Query: 632 LMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLV 811 L H+YE + LG+GT+ KV AR + + VAIK K+K+ I+REI +M + Sbjct: 53 LRHRYEFLETLGKGTYGKVKKARE-SSGRLVAIKSIRKDKIKDEQDLLHIRREIEIMSSL 111 Query: 812 KHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKV-QRGRLKEDAARKYFQQLICAVDFCH 988 HP+I+ ++EV +KI V+E+ G+L++ + +R RL E AR +F+Q++ A+ +CH Sbjct: 112 NHPHIIAIHEVFENSSKIVIVMEYASRGDLYDYISERPRLNERDARHFFRQIVSALHYCH 171 Query: 989 SRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRK 1168 G+ HRDLK EN+LLD + N+K++DFGLS + + L T CG+P Y +PE++N K Sbjct: 172 QNGIVHRDLKLENILLDASGNIKIADFGLSNLYHKGK---FLQTFCGSPLYASPEIVNGK 228 Query: 1169 GYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXX 1348 Y G + D WS GV+L++L+ G +PF ++ + K+I ++ P SD Sbjct: 229 PYVGPEVDSWSLGVLLYILVHGTMPFDGQDHKTLVKQISSGAYREPC-KPSDACGLIRWL 287 Query: 1349 XDPNPSTRISIEKIMEHPWFRKGLDAKL 1432 NP R ++E + H W G ++ Sbjct: 288 LMVNPIRRATLEDVASHWWVNWGYSTRI 315
>Q91820:STK6_XENLA Serine/threonine-protein kinase 6 - Xenopus laevis (African clawed| frog) Length = 407 Score = 184 bits (467), Expect = 1e-45 Identities = 93/266 (34%), Positives = 152/266 (57%), Gaps = 1/266 (0%) Frame = +2 Query: 635 MHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVK 814 + +E+G+ LG+G F VY AR E+ +A+KV K ++ K G+ Q++RE+ + ++ Sbjct: 137 LEDFEIGRPLGKGKFGNVYLARERESKFILALKVLFKSQLEKAGVEHQLRREVEIQSHLR 196 Query: 815 HPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQR-GRLKEDAARKYFQQLICAVDFCHS 991 HPNI+++Y +++Y +L++ GGELF ++Q+ R + + Y +QL A+ +CHS Sbjct: 197 HPNILRLYGYFHDASRVYLILDYAPGGELFRELQKCTRFDDQRSAMYIKQLAEALLYCHS 256 Query: 992 RGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKG 1171 + V HRD+KPENLLL N LK++DFG S + R T CGT Y+ PE+I + Sbjct: 257 KKVIHRDIKPENLLLGSNGELKIADFGWSVHAPSSRRT----TLCGTLDYLPPEMIEGRM 312 Query: 1172 YDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXXX 1351 +D D+WS GV+ + + G PF+ Y++I K EF+ P + S + Sbjct: 313 HD-ETVDLWSLGVLCYEFLVGKPPFETDTHQETYRRISKVEFQYPPYVSEEARDLVSKLL 371 Query: 1352 DPNPSTRISIEKIMEHPWFRKGLDAK 1429 NP+ R+ ++ ++EHPW K K Sbjct: 372 KHNPNHRLPLKGVLEHPWIIKNSQLK 397
>Q5R7G9:NUAK2_PONPY NUAK family SNF1-like kinase 2 - Pongo pygmaeus (Orangutan)| Length = 628 Score = 183 bits (464), Expect = 3e-45 Identities = 98/263 (37%), Positives = 152/263 (57%), Gaps = 1/263 (0%) Frame = +2 Query: 632 LMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLV 811 L H+YE + LG+GT+ KV AR + + VAIK K+K+ I+REI +M + Sbjct: 49 LRHRYEFLETLGKGTYGKVKKARE-SSGRLVAIKSIRKDKIKDEQDLMHIRREIEIMSSL 107 Query: 812 KHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKV-QRGRLKEDAARKYFQQLICAVDFCH 988 HP+I+ ++EV +KI V+E+ G+L++ + +R +L E AR +F+Q++ AV +CH Sbjct: 108 NHPHIIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCH 167 Query: 989 SRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRK 1168 V HRDLK EN+LLD N N+K++DFGLS + + L T CG+P Y +PE++N K Sbjct: 168 QNRVVHRDLKLENILLDANGNIKIADFGLSNLYHQGK---FLQTFCGSPLYASPEIVNGK 224 Query: 1169 GYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXX 1348 Y G + D WS GV+L++L+ G +PF + + K+I ++ P SD Sbjct: 225 PYTGPEVDSWSLGVLLYILVHGTMPFDGHDHKILVKQISNGAYREPP-KPSDACGLIRWL 283 Query: 1349 XDPNPSTRISIEKIMEHPWFRKG 1417 NP+ R ++E + H W G Sbjct: 284 LMVNPTRRATLEDVASHWWVNWG 306
>Q9H093:NUAK2_HUMAN NUAK family SNF1-like kinase 2 - Homo sapiens (Human)| Length = 628 Score = 183 bits (464), Expect = 3e-45 Identities = 98/263 (37%), Positives = 152/263 (57%), Gaps = 1/263 (0%) Frame = +2 Query: 632 LMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLV 811 L H+YE + LG+GT+ KV AR + + VAIK K+K+ I+REI +M + Sbjct: 49 LRHRYEFLETLGKGTYGKVKKARE-SSGRLVAIKSIRKDKIKDEQDLMHIRREIEIMSSL 107 Query: 812 KHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKV-QRGRLKEDAARKYFQQLICAVDFCH 988 HP+I+ ++EV +KI V+E+ G+L++ + +R +L E AR +F+Q++ AV +CH Sbjct: 108 NHPHIIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCH 167 Query: 989 SRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRK 1168 V HRDLK EN+LLD N N+K++DFGLS + + L T CG+P Y +PE++N K Sbjct: 168 QNRVVHRDLKLENILLDANGNIKIADFGLSNLYHQGK---FLQTFCGSPLYASPEIVNGK 224 Query: 1169 GYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXX 1348 Y G + D WS GV+L++L+ G +PF + + K+I ++ P SD Sbjct: 225 PYTGPEVDSWSLGVLLYILVHGTMPFDGHDHKILVKQISNGAYREPP-KPSDACGLIRWL 283 Query: 1349 XDPNPSTRISIEKIMEHPWFRKG 1417 NP+ R ++E + H W G Sbjct: 284 LMVNPTRRATLEDVASHWWVNWG 306
>Q75V63:SAPK3_ORYSA Serine/threonine-protein kinase SAPK3 - Oryza sativa (Rice)| Length = 334 Score = 182 bits (462), Expect = 5e-45 Identities = 107/277 (38%), Positives = 155/277 (55%), Gaps = 13/277 (4%) Frame = +2 Query: 641 KYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHP 820 +YE K LG G F R+ + + VA+K ++ K + + ++REI + ++HP Sbjct: 4 RYEALKELGAGNFGVARLVRDKRSKELVAVKYIERGKKID----ENVQREIINHRSLRHP 59 Query: 821 NIVQMYEVMATKTKIYFVLEHVKGGELFNKV-QRGRLKEDAARKYFQQLICAVDFCHSRG 997 NI++ EV T T + V+E+ GGELF ++ GR ED AR +FQQLI V +CHS Sbjct: 60 NIIRFKEVCLTPTHLAIVMEYAAGGELFEQICTAGRFSEDEARYFFQQLISGVSYCHSLE 119 Query: 998 VYHRDLKPENLLLDENSN--LKVSDFGLSTISECRRLDGLLHT----SCGTPAYVAPEVI 1159 + HRDLK EN LLD + +K+ DFG S LLH+ + GTPAY+APEV+ Sbjct: 120 ICHRDLKLENTLLDGSPTPRVKICDFGYSK-------SALLHSKPKSTVGTPAYIAPEVL 172 Query: 1160 NRKGYDGAKADIWSCGVILFVLMAGYLPFQD----KNLMNMYKKIGKAEFKCPSW--FSS 1321 +RK YDG AD+WSCGV L+V++ G PF+D +N +I ++ P + SS Sbjct: 173 SRKEYDGKVADVWSCGVTLYVMLVGSYPFEDPGDPRNFRKTISRILGVQYSIPDYVRVSS 232 Query: 1322 DXXXXXXXXXDPNPSTRISIEKIMEHPWFRKGLDAKL 1432 D +PS RI+I +I +H WF K L ++ Sbjct: 233 DCRRLLSQIFVADPSKRITIPEIKKHTWFLKNLPKEI 269
>Q7Y0B9:SAPK8_ORYSJ Serine/threonine-protein kinase SAPK8 - Oryza sativa subsp. japonica| (Rice) Length = 371 Score = 182 bits (461), Expect = 7e-45 Identities = 111/281 (39%), Positives = 158/281 (56%), Gaps = 13/281 (4%) Frame = +2 Query: 632 LMH---KYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDK-EKVLKGGLTDQIKREISV 799 +MH +YE+ + +G G F R+ T + VA+K ++ EK+ D ++REI Sbjct: 26 IMHDSDRYELVRDIGSGNFGVARLMRDRRTMELVAVKYIERGEKI-----DDNVQREIIN 80 Query: 800 MKLVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQRG-RLKEDAARKYFQQLICAV 976 + +KHPNI++ EV+ T T + V+E+ GGELF ++ + R ED AR +FQQLI V Sbjct: 81 HRSLKHPNIIRFKEVILTPTHLAIVMEYASGGELFERICKNVRFSEDEARYFFQQLISGV 140 Query: 977 DFCHSRGVYHRDLKPENLLLDENS--NLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAP 1150 +CHS V HRDLK EN LLD + LK+ DFG S S L ++ GTPAY+AP Sbjct: 141 SYCHSMQVCHRDLKLENTLLDGSPAPRLKICDFGYSKSSV---LHSQPKSTVGTPAYIAP 197 Query: 1151 EVINRKGYDGAKADIWSCGVILFVLMAGYLPFQD----KNLMNMYKKIGKAEFKCPS--W 1312 EV+ +K YDG AD+WSCGV L+V++ G PF+D KN ++I ++ P Sbjct: 198 EVLLKKEYDGKTADVWSCGVTLYVMVVGAYPFEDPEEPKNFRKTIQRILNVQYSIPENVD 257 Query: 1313 FSSDXXXXXXXXXDPNPSTRISIEKIMEHPWFRKGLDAKLL 1435 S + +PS RI+I +I H WF K L A L+ Sbjct: 258 ISPECRHLISRIFVGDPSLRITIPEIRSHGWFLKNLPADLM 298
>P43291:ASK1_ARATH Serine/threonine-protein kinase ASK1 - Arabidopsis thaliana| (Mouse-ear cress) Length = 363 Score = 180 bits (457), Expect = 2e-44 Identities = 107/279 (38%), Positives = 154/279 (55%), Gaps = 13/279 (4%) Frame = +2 Query: 635 MHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVK 814 M KYE+ K +G G F + + + VA+K ++ + + + REI + ++ Sbjct: 1 MDKYELVKDIGAGNFGVARLMKVKNSKELVAMKYIERGPKID----ENVAREIINHRSLR 56 Query: 815 HPNIVQMYEVMATKTKIYFVLEHVKGGELFNKV-QRGRLKEDAARKYFQQLICAVDFCHS 991 HPNI++ EV+ T T + +E+ GGELF ++ GR ED AR +FQQLI V +CH+ Sbjct: 57 HPNIIRFKEVVLTPTHLAIAMEYAAGGELFERICSAGRFSEDEARYFFQQLISGVSYCHA 116 Query: 992 RGVYHRDLKPENLLLDENS--NLKVSDFGLSTISECRRLDGLLHT----SCGTPAYVAPE 1153 + HRDLK EN LLD + LK+ DFG S S LLH+ + GTPAY+APE Sbjct: 117 MQICHRDLKLENTLLDGSPAPRLKICDFGYSKSS-------LLHSRPKSTVGTPAYIAPE 169 Query: 1154 VINRKGYDGAKADIWSCGVILFVLMAGYLPFQD----KNLMNMYKKIGKAEFKCPSW--F 1315 V++R+ YDG AD+WSCGV L+V++ G PF+D KN +KI ++K P + Sbjct: 170 VLSRREYDGKMADVWSCGVTLYVMLVGAYPFEDQEDPKNFRKTIQKIMAVQYKIPDYVHI 229 Query: 1316 SSDXXXXXXXXXDPNPSTRISIEKIMEHPWFRKGLDAKL 1432 S D N RI+I +I +H WF K L +L Sbjct: 230 SQDCKNLLSRIFVANSLKRITIAEIKKHSWFLKNLPREL 268
>Q8BZN4:NUAK2_MOUSE NUAK family SNF1-like kinase 2 - Mus musculus (Mouse)| Length = 639 Score = 180 bits (456), Expect = 2e-44 Identities = 109/323 (33%), Positives = 175/323 (54%), Gaps = 21/323 (6%) Frame = +2 Query: 512 VEAIQRPQVPLQAPGIAA---------AFFCVRLPACL---PAIMGEQKGNILMHKYEMG 655 +E++ Q P QAP +A A ++ P L A+ + L H+YE Sbjct: 1 MESVALLQRPSQAPSASALASESARPLADGLIKSPKPLMKKQAVKRHHHKHNLRHRYEFL 60 Query: 656 KMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPNIVQM 835 + LG+GT+ KV AR + + VAIK K+K+ I+REI +M + HP+I+ + Sbjct: 61 ETLGKGTYGKVKKARE-SSGRLVAIKSIRKDKIKDEQDLLHIRREIEIMSSLNHPHIIAI 119 Query: 836 YEVMATK--------TKIYFVLEHVKGGELFNKV-QRGRLKEDAARKYFQQLICAVDFCH 988 +EV ++ +KI V+E+ G+L++ + +R RL E AR +F+Q++ A+ +CH Sbjct: 120 HEVGRSRLVTVFENSSKIVIVMEYASRGDLYDYISERPRLSERDARHFFRQIVSALHYCH 179 Query: 989 SRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRK 1168 G+ HRDLK EN+LLD N N+K++DFGLS + + L T CG+P Y +PE++N K Sbjct: 180 QNGIVHRDLKLENILLDANGNIKIADFGLSNLYHKGK---FLQTFCGSPLYASPEIVNGK 236 Query: 1169 GYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXX 1348 Y G + D WS GV+L++L+ G +PF ++ + K+I ++ P SD Sbjct: 237 PYVGPEVDSWSLGVLLYILVHGTMPFDGQDHKTLVKQISNGAYREPP-KPSDACGLIRWL 295 Query: 1349 XDPNPSTRISIEKIMEHPWFRKG 1417 NP+ R ++E + H W G Sbjct: 296 LMVNPTRRATLEDVASHWWVNWG 318
>Q02066:AAIP_WHEAT Abscisic acid-inducible protein kinase - Triticum aestivum (Wheat)| Length = 332 Score = 179 bits (455), Expect = 3e-44 Identities = 102/265 (38%), Positives = 146/265 (55%), Gaps = 9/265 (3%) Frame = +2 Query: 665 GQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPNIVQMYEV 844 G G F R++ T + A+K ++ + + ++REI + +KHPNI++ EV Sbjct: 1 GSGNFGVAKLVRDVRTKEHFAVKFIERGHKID----EHVQREIMNHRSLKHPNIIRFKEV 56 Query: 845 MATKTKIYFVLEHVKGGELFNKV-QRGRLKEDAARKYFQQLICAVDFCHSRGVYHRDLKP 1021 + T T + V+E+ GGELF ++ GR ED R +FQQLI V +CHS V HRDLK Sbjct: 57 VLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFFQQLISGVSYCHSMQVCHRDLKL 116 Query: 1022 ENLLLDEN--SNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKGYDGAKADI 1195 EN LLD + LK+ DFG S S L ++ GTPAY+APEV++R+ YDG AD+ Sbjct: 117 ENTLLDGSVAPRLKICDFGYSKSSV---LHSQPKSTVGTPAYIAPEVLSRREYDGKVADV 173 Query: 1196 WSCGVILFVLMAGYLPFQD----KNLMNMYKKIGKAEFKCPSW--FSSDXXXXXXXXXDP 1357 WSCGV L+V++ G PF+D +N +I ++ P + S D Sbjct: 174 WSCGVTLYVMLVGAYPFEDPDEPRNFRKTITRILSVQYSVPDYVRVSMDCIHLLSRIFVG 233 Query: 1358 NPSTRISIEKIMEHPWFRKGLDAKL 1432 NP RI+I +I HPWF K L ++ Sbjct: 234 NPQQRITIPEIKNHPWFLKRLPVEM 258
>O64629:AUR3_ARATH Serine/threonine-protein kinase Aurora-3 - Arabidopsis thaliana| (Mouse-ear cress) Length = 288 Score = 179 bits (454), Expect = 4e-44 Identities = 97/265 (36%), Positives = 152/265 (57%), Gaps = 3/265 (1%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 +E+G+ LG+G F +VY AR ++ VA+KV KE++ K + Q++RE+ + ++HPN Sbjct: 22 FEIGRPLGKGKFGRVYLAREAKSKYIVALKVIFKEQIEKYKIHHQLRREMEIQTSLRHPN 81 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNKV-QRGRLKEDAARKYFQQLICAVDFCHSRGV 1000 I++++ +I+ +LE+ GGEL+ + Q G L E A Y L A+ +CH + V Sbjct: 82 ILRLFGWFHDNERIFLILEYAHGGELYGVLKQNGHLTEQQAATYIASLSQALAYCHGKCV 141 Query: 1001 YHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKGYDG 1180 HRD+KPENLLLD LK++DFG S S +R T CGT Y+APE++ + +D Sbjct: 142 IHRDIKPENLLLDHEGRLKIADFGWSVQSSNKR-----KTMCGTLDYLAPEMVENRDHDY 196 Query: 1181 AKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSW--FSSDXXXXXXXXXD 1354 A D W+ G++ + + G PF+ ++ + +K+I K + P S + Sbjct: 197 A-VDNWTLGILCYEFLYGNPPFEAESQKDTFKRILKIDLSFPLTPNVSEEAKNLISQLLV 255 Query: 1355 PNPSTRISIEKIMEHPWFRKGLDAK 1429 +PS R+SIEKIM+HPW K D K Sbjct: 256 KDPSKRLSIEKIMQHPWIVKNADPK 280
>O00444:PLK4_HUMAN Serine/threonine-protein kinase PLK4 - Homo sapiens (Human)| Length = 970 Score = 179 bits (453), Expect = 6e-44 Identities = 88/265 (33%), Positives = 153/265 (57%), Gaps = 3/265 (1%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 +++G +LG+G+FA VY A +I T VAIK+ DK+ + K G+ +++ E+ + +KHP+ Sbjct: 12 FKVGNLLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQRVQNEVKIHCQLKHPS 71 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNKVQRGRLK---EDAARKYFQQLICAVDFCHSR 994 I+++Y +Y VLE GE+ N+ + R+K E+ AR + Q+I + + HS Sbjct: 72 ILELYNYFEDSNYVYLVLEMCHNGEM-NRYLKNRVKPFSENEARHFMHQIITGMLYLHSH 130 Query: 995 GVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKGY 1174 G+ HRDL NLLL N N+K++DFGL+T + + +T CGTP Y++PE+ R + Sbjct: 131 GILHRDLTLSNLLLTRNMNIKIADFGLAT--QLKMPHEKHYTLCGTPNYISPEIATRSAH 188 Query: 1175 DGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXXXD 1354 G ++D+WS G + + L+ G PF + N K+ A+++ P++ S + Sbjct: 189 -GLESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVVLADYEMPTFLSIEAKDLIHQLLR 247 Query: 1355 PNPSTRISIEKIMEHPWFRKGLDAK 1429 NP+ R+S+ +++HP+ + K Sbjct: 248 RNPADRLSLSSVLDHPFMSRNSSTK 272
>Q8N568:DCLK2_HUMAN Serine/threonine-protein kinase DCLK2 - Homo sapiens (Human)| Length = 766 Score = 178 bits (452), Expect = 7e-44 Identities = 100/273 (36%), Positives = 155/273 (56%), Gaps = 11/273 (4%) Frame = +2 Query: 620 KGNILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISV 799 + + L+ KY++GK++G G FA V + T + A+K+ DK K G I+ E+S+ Sbjct: 386 ESSTLLEKYKIGKVIGDGNFAVVKECIDRSTGKEFALKIIDKAKCC--GKEHLIENEVSI 443 Query: 800 MKLVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQRG-RLKEDAARKYFQQLICAV 976 ++ VKHPNI+ + E M T T+++ V+E VKGG+LF+ + + E L A+ Sbjct: 444 LRRVKHPNIIMLVEEMETATELFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLANAL 503 Query: 977 DFCHSRGVYHRDLKPENLLL----DENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYV 1144 + H + HRD+KPENLL+ D +LK+ DFGL+T+ ++G L+T CGTP YV Sbjct: 504 RYLHGLSIVHRDIKPENLLVCEYPDGTKSLKLGDFGLATV-----VEGPLYTVCGTPTYV 558 Query: 1145 APEVINRKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLM--NMYKKI--GKAEFKCPSW 1312 APE+I GY G K DIW+ GVI ++L+ G+ PF+ +N + +++ +I GK EF P W Sbjct: 559 APEIIAETGY-GLKVDIWAAGVITYILLCGFPPFRSENNLQEDLFDQILAGKLEFPAPYW 617 Query: 1313 --FSSDXXXXXXXXXDPNPSTRISIEKIMEHPW 1405 + N R + +I+ HPW Sbjct: 618 DNITDSAKELISQMLQVNVEARCTAGQILSHPW 650
>O88445:AURKC_MOUSE Serine/threonine-protein kinase 13 - Mus musculus (Mouse)| Length = 282 Score = 178 bits (452), Expect = 7e-44 Identities = 94/261 (36%), Positives = 151/261 (57%), Gaps = 1/261 (0%) Frame = +2 Query: 635 MHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVK 814 ++ +E+G+ LG+G F +VY AR E VA+KV K ++ K GL Q++RE+ + ++ Sbjct: 13 INDFEIGRPLGRGKFGRVYLARLKENHFIVALKVLFKSEIEKEGLEHQLRREVEIQAHLQ 72 Query: 815 HPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQR-GRLKEDAARKYFQQLICAVDFCHS 991 H NI+++Y T+IY +LE+ GGEL+ ++QR +L + Q+L A+ +CH Sbjct: 73 HRNILRLYNYFYDDTRIYLILEYAPGGELYKELQRHQKLDQQRTATIIQELSDALTYCHE 132 Query: 992 RGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKG 1171 + V HRD+KPENLLL N +K+SDFG S + R T CGT Y+ PE+I +K Sbjct: 133 KKVIHRDIKPENLLLGLNGEVKISDFGWSVHTPSLR----RKTMCGTLDYLPPEMIAQKP 188 Query: 1172 YDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXXX 1351 Y+ D+W GV+ + L+ G PF+ Y++I + +FK PS + Sbjct: 189 YN-EMVDLWCIGVLCYELLVGKPPFESSTSSETYRRIRQVDFKFPSSVPAGAQDLISKLL 247 Query: 1352 DPNPSTRISIEKIMEHPWFRK 1414 +PS R+S+ ++++HPW R+ Sbjct: 248 RYHPSERLSLAQVLKHPWVRE 268
>Q6PGN3:DCLK2_MOUSE Serine/threonine-protein kinase DCLK2 - Mus musculus (Mouse)| Length = 756 Score = 177 bits (449), Expect = 2e-43 Identities = 100/269 (37%), Positives = 152/269 (56%), Gaps = 11/269 (4%) Frame = +2 Query: 632 LMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLV 811 L+ KY +GK++G G FA V + T + A+K+ DK K G I+ E+S+++ V Sbjct: 389 LLEKYRIGKVIGDGNFAVVKECVDRYTGKEFALKIIDKAKCC--GKEHLIENEVSILRRV 446 Query: 812 KHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQRG-RLKEDAARKYFQQLICAVDFCH 988 KHPNI+ + E M T T ++ V+E VKGG+LF+ + + E L A+ + H Sbjct: 447 KHPNIIMLVEEMETATDLFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLH 506 Query: 989 SRGVYHRDLKPENLLL----DENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEV 1156 S + HRD+KPENLL+ D +LK+ DFGL+T+ ++G L+T CGTP YVAPE+ Sbjct: 507 SLSIVHRDIKPENLLVCEYPDGTKSLKLGDFGLATV-----VEGPLYTVCGTPTYVAPEI 561 Query: 1157 INRKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLM--NMYKKI--GKAEFKCPSW--FS 1318 I GY G K D+W+ GVI ++L+ G+ PF+ +N + +++ +I GK EF P W + Sbjct: 562 IAETGY-GLKVDVWAAGVITYILLCGFPPFRSENNLQEDLFDQILAGKLEFPAPYWDNIT 620 Query: 1319 SDXXXXXXXXXDPNPSTRISIEKIMEHPW 1405 N R + +I+ HPW Sbjct: 621 DSAKELISQMLQVNVEARCTAGEILSHPW 649
>Q14012:KCC1A_HUMAN Calcium/calmodulin-dependent protein kinase type 1 - Homo sapiens| (Human) Length = 370 Score = 177 bits (448), Expect = 2e-43 Identities = 102/262 (38%), Positives = 154/262 (58%), Gaps = 8/262 (3%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 Y+ +LG G F++V A + T + VAIK KE + G ++ EI+V+ +KHPN Sbjct: 20 YDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKEAL--EGKEGSMENEIAVLHKIKHPN 77 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNK-VQRGRLKEDAARKYFQQLICAVDFCHSRGV 1000 IV + ++ + +Y +++ V GGELF++ V++G E A + Q++ AV + H G+ Sbjct: 78 IVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGI 137 Query: 1001 YHRDLKPENLL---LDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKG 1171 HRDLKPENLL LDE+S + +SDFGLS + + +L T+CGTP YVAPEV+ +K Sbjct: 138 VHRDLKPENLLYYSLDEDSKIMISDFGLSKMEDP---GSVLSTACGTPGYVAPEVLAQKP 194 Query: 1172 YDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKA--EFKCPSW--FSSDXXXXX 1339 Y A D WS GVI ++L+ GY PF D+N ++++I KA EF P W S Sbjct: 195 YSKA-VDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFI 253 Query: 1340 XXXXDPNPSTRISIEKIMEHPW 1405 + +P R + E+ ++HPW Sbjct: 254 RHLMEKDPEKRFTCEQALQHPW 275
>Q64702:PLK4_MOUSE Serine/threonine-protein kinase PLK4 - Mus musculus (Mouse)| Length = 925 Score = 176 bits (447), Expect = 3e-43 Identities = 90/281 (32%), Positives = 158/281 (56%), Gaps = 3/281 (1%) Frame = +2 Query: 596 LPAIMGEQKGNILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTD 775 + A +GE+ + +++G +LG+G+FA VY A +I T VAIK+ DK+ + K G+ Sbjct: 1 MAACIGER-----IEDFKVGNLLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQ 55 Query: 776 QIKREISVMKLVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQRGRLK---EDAAR 946 +++ E+ + +KHP+++++Y +Y VLE GE+ N+ + R+K E AR Sbjct: 56 RVQNEVKIHCQLKHPSVLELYNYFEDNNYVYLVLEMCHNGEM-NRYLKNRMKPFSEREAR 114 Query: 947 KYFQQLICAVDFCHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSC 1126 + Q+I + + HS G+ HRDL N+LL N N+K++DFGL+T + +T C Sbjct: 115 HFMHQIITGMLYLHSHGILHRDLTLSNILLTRNMNIKIADFGLAT--QLNMPHEKHYTLC 172 Query: 1127 GTPAYVAPEVINRKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCP 1306 GTP Y++PE+ R + G ++DIWS G + + L+ G PF + N K+ A+++ P Sbjct: 173 GTPNYISPEIATRSAH-GLESDIWSLGCMFYTLLIGRPPFDTDTVKNTLNKVVLADYEMP 231 Query: 1307 SWFSSDXXXXXXXXXDPNPSTRISIEKIMEHPWFRKGLDAK 1429 ++ S + NP+ R+S+ +++HP+ + K Sbjct: 232 AFLSREAQDLIHQLLRRNPADRLSLSSVLDHPFMSRNPSPK 272
>O59790:ARK1_SCHPO Serine/threonine-protein kinase ark1 - Schizosaccharomyces pombe| (Fission yeast) Length = 355 Score = 176 bits (447), Expect = 3e-43 Identities = 97/281 (34%), Positives = 156/281 (55%), Gaps = 2/281 (0%) Frame = +2 Query: 590 ACLPAIMGEQKGNILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGL 769 A +P+ G Q + +E+GK LG+G F +VY A+ +T VA+K K ++++ + Sbjct: 71 AGVPSSAGPQWREFHIGMFEIGKPLGKGKFGRVYLAKEKKTGFIVALKTLHKSELVQSKI 130 Query: 770 TDQIKREISVMKLVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQRG-RLKEDAAR 946 Q++REI + ++H NI+++Y + +IY +LE GEL+ ++R R E+ A Sbjct: 131 EKQVRREIEIQSNLRHKNILRLYGHFHDEKRIYLILEFAGRGELYQHLRRAKRFSEEVAS 190 Query: 947 KYFQQLICAVDFCHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSC 1126 KY Q+ A+ + H + V HRD+KPEN+LL + +K+SDFG S + R T C Sbjct: 191 KYIFQMANALSYLHKKHVIHRDIKPENILLGIDGEIKLSDFGWSVHAPSNRRT----TLC 246 Query: 1127 GTPAYVAPEVINRKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMN-MYKKIGKAEFKC 1303 GT Y+ PE++ K + K D+WS GV+ + + G PF+D + + YK+I K + K Sbjct: 247 GTLDYLPPEMVEGKEHT-EKVDLWSLGVLTYEFLVGAPPFEDMSGHSATYKRIAKVDLKI 305 Query: 1304 PSWFSSDXXXXXXXXXDPNPSTRISIEKIMEHPWFRKGLDA 1426 PS+ D NP R+S+E++M HPW K D+ Sbjct: 306 PSFVPPDARDLISRLLQHNPEKRMSLEQVMRHPWIVKYKDS 346
>Q03002:YP141_YEAST Putative serine/threonine-protein kinase YPL141C - Saccharomyces| cerevisiae (Baker's yeast) Length = 865 Score = 176 bits (446), Expect = 4e-43 Identities = 105/286 (36%), Positives = 160/286 (55%), Gaps = 20/286 (6%) Frame = +2 Query: 614 EQKGNILMHKYEMGKMLGQGTFAKVYHA--RNIETSQS--------VAIKVTDKEKVLKG 763 +++ ++ Y +G LG+G F KV +N S + VAIK+ ++ + Sbjct: 31 QRRKHVTFGPYILGSTLGEGEFGKVKLGWPKNFSNSSNSTFDFPKQVAIKLIKRDSISND 90 Query: 764 GLTD-QIKREISVMKLVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQRGR-LKED 937 + +I REI+ +K + HPNIV++ EV+ I VLE+ GGE + +Q+ R LKE Sbjct: 91 YRKEVKIYREINALKHLSHPNIVKLEEVLQNSRYIGIVLEYACGGEFYKYIQKKRRLKEM 150 Query: 938 AARKYFQQLICAVDFCHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLH 1117 A + F QLI V + HS+G+ HRDLK ENLLLD+N NL ++DFG ++E + L+ Sbjct: 151 NACRLFSQLISGVHYIHSKGLVHRDLKLENLLLDKNENLVITDFGF--VNEFCSRNELMK 208 Query: 1118 TSCGTPAYVAPE-VINRKGYDGAKADIWSCGVILFVLMAGYLPFQD-------KNLMNMY 1273 TSCG+P Y APE VI+ + Y+ KADIWSCGVIL+ ++AGYLP+ D ++ +Y Sbjct: 209 TSCGSPCYAAPELVISAEPYEARKADIWSCGVILYAILAGYLPWDDDPNNPEGSDIGRLY 268 Query: 1274 KKIGKAEFKCPSWFSSDXXXXXXXXXDPNPSTRISIEKIMEHPWFR 1411 I K P + +P RI++++I +H W + Sbjct: 269 NYINSTPLKFPDYILPIPRDLLRRMLVSDPKKRINLKQIKKHEWLK 314
>Q7TNJ7:KCC1G_RAT Calcium/calmodulin-dependent protein kinase type 1G - Rattus| norvegicus (Rat) Length = 476 Score = 176 bits (445), Expect = 5e-43 Identities = 96/258 (37%), Positives = 150/258 (58%), Gaps = 8/258 (3%) Frame = +2 Query: 656 KMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPNIVQM 835 ++LG G F++V+ + T + A+K K + ++ EI+V+K +KH NIV + Sbjct: 27 EVLGSGAFSEVFLVKQRVTGKLFALKCIKKSPAFRDS---SLENEIAVLKRIKHENIVTL 83 Query: 836 YEVMATKTKIYFVLEHVKGGELFNKV-QRGRLKEDAARKYFQQLICAVDFCHSRGVYHRD 1012 ++ + T Y V++ V GGELF+++ +RG E A QQ++ AV + H G+ HRD Sbjct: 84 EDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYLHENGIVHRD 143 Query: 1013 LKPENLLL---DENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKGYDGA 1183 LKPENLL +ENS + ++DFGLS + + +G++ T+CGTP YVAPEV+ +K Y A Sbjct: 144 LKPENLLYLTPEENSKIMITDFGLSKMEQ----NGVMSTACGTPGYVAPEVLAQKPYSKA 199 Query: 1184 KADIWSCGVILFVLMAGYLPFQDKNLMNMYKKI--GKAEFKCPSW--FSSDXXXXXXXXX 1351 D WS GVI ++L+ GY PF ++ +++KI G EF+ P W S Sbjct: 200 -VDCWSIGVITYILLCGYPPFYEETESKLFEKIKEGYYEFESPFWDDISESAKDFICHLL 258 Query: 1352 DPNPSTRISIEKIMEHPW 1405 + +P+ R + EK + HPW Sbjct: 259 EKDPNERYTCEKALRHPW 276
>Q91VB2:KCC1G_MOUSE Calcium/calmodulin-dependent protein kinase type 1G - Mus musculus| (Mouse) Length = 477 Score = 176 bits (445), Expect = 5e-43 Identities = 96/258 (37%), Positives = 150/258 (58%), Gaps = 8/258 (3%) Frame = +2 Query: 656 KMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPNIVQM 835 ++LG G F++V+ + T + A+K K + ++ EI+V+K +KH NIV + Sbjct: 27 EVLGSGAFSEVFLVKQRVTGKLFALKCIKKSPAFRDS---SLENEIAVLKRIKHENIVTL 83 Query: 836 YEVMATKTKIYFVLEHVKGGELFNKV-QRGRLKEDAARKYFQQLICAVDFCHSRGVYHRD 1012 ++ + T Y V++ V GGELF+++ +RG E A QQ++ AV + H G+ HRD Sbjct: 84 EDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYLHENGIVHRD 143 Query: 1013 LKPENLLL---DENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKGYDGA 1183 LKPENLL +ENS + ++DFGLS + + +G++ T+CGTP YVAPEV+ +K Y A Sbjct: 144 LKPENLLYLTPEENSKIMITDFGLSKMEQ----NGVMSTACGTPGYVAPEVLAQKPYSKA 199 Query: 1184 KADIWSCGVILFVLMAGYLPFQDKNLMNMYKKI--GKAEFKCPSW--FSSDXXXXXXXXX 1351 D WS GVI ++L+ GY PF ++ +++KI G EF+ P W S Sbjct: 200 -VDCWSIGVITYILLCGYPPFYEETESKLFEKIKEGYYEFESPFWDDISESAKDFICHLL 258 Query: 1352 DPNPSTRISIEKIMEHPW 1405 + +P+ R + EK + HPW Sbjct: 259 EKDPNERYTCEKALRHPW 276
>Q96NX5:KCC1G_HUMAN Calcium/calmodulin-dependent protein kinase type 1G - Homo sapiens| (Human) Length = 476 Score = 176 bits (445), Expect = 5e-43 Identities = 96/258 (37%), Positives = 150/258 (58%), Gaps = 8/258 (3%) Frame = +2 Query: 656 KMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPNIVQM 835 ++LG G F++V+ + T + A+K K + ++ EI+V+K +KH NIV + Sbjct: 27 EVLGSGAFSEVFLVKQRLTGKLFALKCIKKSPAFRDS---SLENEIAVLKKIKHENIVTL 83 Query: 836 YEVMATKTKIYFVLEHVKGGELFNKV-QRGRLKEDAARKYFQQLICAVDFCHSRGVYHRD 1012 ++ + T Y V++ V GGELF+++ +RG E A QQ++ AV + H G+ HRD Sbjct: 84 EDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYLHENGIVHRD 143 Query: 1013 LKPENLLL---DENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKGYDGA 1183 LKPENLL +ENS + ++DFGLS + + +G++ T+CGTP YVAPEV+ +K Y A Sbjct: 144 LKPENLLYLTPEENSKIMITDFGLSKMEQ----NGIMSTACGTPGYVAPEVLAQKPYSKA 199 Query: 1184 KADIWSCGVILFVLMAGYLPFQDKNLMNMYKKI--GKAEFKCPSW--FSSDXXXXXXXXX 1351 D WS GVI ++L+ GY PF ++ +++KI G EF+ P W S Sbjct: 200 -VDCWSIGVITYILLCGYPPFYEETESKLFEKIKEGYYEFESPFWDDISESAKDFICHLL 258 Query: 1352 DPNPSTRISIEKIMEHPW 1405 + +P+ R + EK + HPW Sbjct: 259 EKDPNERYTCEKALSHPW 276
>Q63450:KCC1A_RAT Calcium/calmodulin-dependent protein kinase type 1 - Rattus| norvegicus (Rat) Length = 374 Score = 175 bits (444), Expect = 6e-43 Identities = 101/262 (38%), Positives = 154/262 (58%), Gaps = 8/262 (3%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 Y+ +LG G F++V A + T + VAIK K+ + G ++ EI+V+ +KHPN Sbjct: 20 YDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKKAL--EGKEGSMENEIAVLHKIKHPN 77 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNK-VQRGRLKEDAARKYFQQLICAVDFCHSRGV 1000 IV + ++ + +Y +++ V GGELF++ V++G E A + Q++ AV + H G+ Sbjct: 78 IVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGI 137 Query: 1001 YHRDLKPENLL---LDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKG 1171 HRDLKPENLL LDE+S + +SDFGLS + + +L T+CGTP YVAPEV+ +K Sbjct: 138 VHRDLKPENLLYYSLDEDSKIMISDFGLSKMEDP---GSVLSTACGTPGYVAPEVLAQKP 194 Query: 1172 YDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKA--EFKCPSW--FSSDXXXXX 1339 Y A D WS GVI ++L+ GY PF D+N ++++I KA EF P W S Sbjct: 195 YSKA-VDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFI 253 Query: 1340 XXXXDPNPSTRISIEKIMEHPW 1405 + +P R + E+ ++HPW Sbjct: 254 RHLMEKDPEKRFTCEQALQHPW 275
>Q91YS8:KCC1A_MOUSE Calcium/calmodulin-dependent protein kinase type 1 - Mus musculus| (Mouse) Length = 374 Score = 175 bits (444), Expect = 6e-43 Identities = 101/262 (38%), Positives = 154/262 (58%), Gaps = 8/262 (3%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 Y+ +LG G F++V A + T + VAIK K+ + G ++ EI+V+ +KHPN Sbjct: 20 YDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKKAL--EGKEGSMENEIAVLHKIKHPN 77 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNK-VQRGRLKEDAARKYFQQLICAVDFCHSRGV 1000 IV + ++ + +Y +++ V GGELF++ V++G E A + Q++ AV + H G+ Sbjct: 78 IVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGI 137 Query: 1001 YHRDLKPENLL---LDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKG 1171 HRDLKPENLL LDE+S + +SDFGLS + + +L T+CGTP YVAPEV+ +K Sbjct: 138 VHRDLKPENLLYYSLDEDSKIMISDFGLSKMEDP---GSVLSTACGTPGYVAPEVLAQKP 194 Query: 1172 YDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKA--EFKCPSW--FSSDXXXXX 1339 Y A D WS GVI ++L+ GY PF D+N ++++I KA EF P W S Sbjct: 195 YSKA-VDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFI 253 Query: 1340 XXXXDPNPSTRISIEKIMEHPW 1405 + +P R + E+ ++HPW Sbjct: 254 RHLMEKDPEKRFTCEQALQHPW 275
>P06244:KAPA_YEAST cAMP-dependent protein kinase type 1 - Saccharomyces cerevisiae| (Baker's yeast) Length = 397 Score = 175 bits (444), Expect = 6e-43 Identities = 88/282 (31%), Positives = 164/282 (58%), Gaps = 6/282 (2%) Frame = +2 Query: 623 GNILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVM 802 G + +++ + LG G+F +V+ R+ + A+KV KE V++ + E ++ Sbjct: 80 GKYSLQDFQILRTLGTGSFGRVHLIRSRHNGRYYAMKVLKKEIVVRLKQVEHTNDERLML 139 Query: 803 KLVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQRGRLKEDAARKYFQQLIC-AVD 979 +V HP I++M+ +I+ ++++++GGELF+ +++ + + K++ +C A++ Sbjct: 140 SIVTHPFIIRMWGTFQDAQQIFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALE 199 Query: 980 FCHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVI 1159 + HS+ + +RDLKPEN+LLD+N ++K++DFG + + + + +T CGTP Y+APEV+ Sbjct: 200 YLHSKDIIYRDLKPENILLDKNGHIKITDFGFA-----KYVPDVTYTLCGTPDYIAPEVV 254 Query: 1160 NRKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXX 1339 + K Y+ D WS G++++ ++AGY PF D N M Y+KI AE + P +F+ D Sbjct: 255 STKPYN-KSIDWWSFGILIYEMLAGYTPFYDSNTMKTYEKILNAELRFPPFFNEDVKDLL 313 Query: 1340 XXXXDPNPSTRI-----SIEKIMEHPWFRKGLDAKLLRYNLQ 1450 + S R+ E + HPWF++ + KLL N++ Sbjct: 314 SRLITRDLSQRLGNLQNGTEDVKNHPWFKEVVWEKLLSRNIE 355
>P06245:KAPB_YEAST cAMP-dependent protein kinase type 2 - Saccharomyces cerevisiae| (Baker's yeast) Length = 380 Score = 175 bits (443), Expect = 8e-43 Identities = 94/295 (31%), Positives = 164/295 (55%), Gaps = 6/295 (2%) Frame = +2 Query: 584 LPACLPAIMGEQKGNILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKG 763 L + LP KG +H +++ + LG G+F +V+ R++ + AIKV K++V+K Sbjct: 50 LTSQLPQKSLVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKQQVVKM 109 Query: 764 GLTDQIKREISVMKLVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQRG-RLKEDA 940 + E ++KLV+HP +++M+ I+ V+++++GGELF+ +++ R Sbjct: 110 KQVEHTNDERRMLKLVEHPFLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPV 169 Query: 941 ARKYFQQLICAVDFCHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHT 1120 A+ Y ++I A+++ H+ + +RDLKPEN+LLD N ++K++DFG + + + + T Sbjct: 170 AKFYAAEVILALEYLHAHNIIYRDLKPENILLDRNGHIKITDFGFA-----KEVQTVTWT 224 Query: 1121 SCGTPAYVAPEVINRKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFK 1300 CGTP Y+APEVI K Y+ D WS GV+++ ++AGY PF D M Y+KI + + Sbjct: 225 LCGTPDYIAPEVITTKPYN-KSVDWWSLGVLIYEMLAGYTPFYDTTPMKTYEKILQGKVV 283 Query: 1301 CPSWFSSDXXXXXXXXXDPNPSTRI-----SIEKIMEHPWFRKGLDAKLLRYNLQ 1450 P +F D + + RI I HPWF + + +LL +++ Sbjct: 284 YPPYFHPDVVDLLSKLITADLTRRIGNLQSGSRDIKAHPWFSEVVWERLLAKDIE 338
>Q9C098:DCLK3_HUMAN Serine/threonine-protein kinase DCLK3 - Homo sapiens (Human)| Length = 648 Score = 174 bits (442), Expect = 1e-42 Identities = 100/280 (35%), Positives = 162/280 (57%), Gaps = 11/280 (3%) Frame = +2 Query: 599 PAIMGEQKGNILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQ 778 P MG N+ H YE G+++G G FA V R+ ET Q+ A+K+ DK ++ G D Sbjct: 342 PRPMGIIAANVEKH-YETGRVIGDGNFAVVKECRHRETRQAYAMKIIDKSRLK--GKEDM 398 Query: 779 IKREISVMKLVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNK-VQRGRLKEDAARKYF 955 + EI +++ + HPNIV+++EV T +IY +LE+V+GG+LF+ ++ + E A Sbjct: 399 VDSEILIIQSLSHPNIVKLHEVYETDMEIYLILEYVQGGDLFDAIIESVKFPEPDAALMI 458 Query: 956 QQLICAVDFCHSRGVYHRDLKPENLLL----DENSNLKVSDFGLSTISECRRLDGLLHTS 1123 L A+ H + + HRDLKPENLL+ D+++ LK++DFGL+ + + + T Sbjct: 459 MDLCKALVHMHDKSIVHRDLKPENLLVQRNEDKSTTLKLADFGLA-----KHVVRPIFTV 513 Query: 1124 CGTPAYVAPEVINRKGYDGAKADIWSCGVILFVLMAGYLPF----QDKNLMNMYKKIGKA 1291 CGTP YVAPE+++ KGY G + D+W+ GVIL++L+ G+ PF +D++ + ++G Sbjct: 514 CGTPTYVAPEILSEKGY-GLEVDMWAAGVILYILLCGFPPFRSPERDQDELFNIIQLGHF 572 Query: 1292 EFKCPSW--FSSDXXXXXXXXXDPNPSTRISIEKIMEHPW 1405 EF P W S +P R + ++++HPW Sbjct: 573 EFLPPYWDNISDAAKDLVSRLLVVDPKKRYTAHQVLQHPW 612
>O08875:DCLK1_RAT Serine/threonine-protein kinase DCLK1 - Rattus norvegicus (Rat)| Length = 433 Score = 174 bits (442), Expect = 1e-42 Identities = 100/269 (37%), Positives = 150/269 (55%), Gaps = 11/269 (4%) Frame = +2 Query: 632 LMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLV 811 + +Y++G+ +G G FA V T++ A+K+ K K G I+ E+S+++ V Sbjct: 79 ITERYKVGRTIGDGNFAVVKECIERSTAREYALKIIKKSKCR--GKEHMIQNEVSILRRV 136 Query: 812 KHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKV-QRGRLKEDAARKYFQQLICAVDFCH 988 KHPNIV + E M T++Y V+E VKGG+LF+ + + E A L A+ + H Sbjct: 137 KHPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTSKYTERDASGMLYNLASAIKYLH 196 Query: 989 SRGVYHRDLKPENLLL----DENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEV 1156 S + HRD+KPENLL+ D + +LK+ DFGL+TI +DG L+T CGTP YVAPE+ Sbjct: 197 SLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATI-----VDGPLYTVCGTPTYVAPEI 251 Query: 1157 INRKGYDGAKADIWSCGVILFVLMAGYLPFQ----DKNLMNMYKKIGKAEFKCPSW--FS 1318 I GY G K DIW+ GVI ++L+ G+ PF+ D+ ++ +G+ +F P W S Sbjct: 252 IAETGY-GLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVS 310 Query: 1319 SDXXXXXXXXXDPNPSTRISIEKIMEHPW 1405 N R S +++EHPW Sbjct: 311 DSAKELINMMLLVNVDQRFSAVQVLEHPW 339
>Q9JLM8:DCLK1_MOUSE Serine/threonine-protein kinase DCLK1 - Mus musculus (Mouse)| Length = 756 Score = 174 bits (442), Expect = 1e-42 Identities = 100/269 (37%), Positives = 150/269 (55%), Gaps = 11/269 (4%) Frame = +2 Query: 632 LMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLV 811 + +Y++G+ +G G FA V T++ A+K+ K K G I+ E+S+++ V Sbjct: 402 ITERYKVGRTIGDGNFAVVKECIERSTAREYALKIIKKSKCR--GKEHMIQNEVSILRRV 459 Query: 812 KHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKV-QRGRLKEDAARKYFQQLICAVDFCH 988 KHPNIV + E M T++Y V+E VKGG+LF+ + + E A L A+ + H Sbjct: 460 KHPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTSKYTERDASGMLYNLASAIKYLH 519 Query: 989 SRGVYHRDLKPENLLL----DENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEV 1156 S + HRD+KPENLL+ D + +LK+ DFGL+TI +DG L+T CGTP YVAPE+ Sbjct: 520 SLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATI-----VDGPLYTVCGTPTYVAPEI 574 Query: 1157 INRKGYDGAKADIWSCGVILFVLMAGYLPFQ----DKNLMNMYKKIGKAEFKCPSW--FS 1318 I GY G K DIW+ GVI ++L+ G+ PF+ D+ ++ +G+ +F P W S Sbjct: 575 IAETGY-GLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVS 633 Query: 1319 SDXXXXXXXXXDPNPSTRISIEKIMEHPW 1405 N R S +++EHPW Sbjct: 634 DSAKELINMMLLVNVDQRFSAVQVLEHPW 662
>Q6NW76:AURKB_DANRE Serine/threonine-protein kinase 12 - Danio rerio (Zebrafish)| (Brachydanio rerio) Length = 320 Score = 174 bits (441), Expect = 1e-42 Identities = 87/257 (33%), Positives = 143/257 (55%), Gaps = 1/257 (0%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 +++G+ LG+G F VY AR + +A+KV K +++K G+ Q++REI + ++HPN Sbjct: 53 FDIGRPLGKGKFGNVYLARERKLKVVIALKVLFKSQMVKEGVEHQLRREIEIQSHLRHPN 112 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNKVQR-GRLKEDAARKYFQQLICAVDFCHSRGV 1000 I++ Y T+++ +LE+ GE++ ++QR GR + Y +++ A+ +CH + V Sbjct: 113 ILRFYNYFHDDTRVFLILEYAPRGEMYKELQRYGRFDDQRTATYMEEVSDALQYCHEKKV 172 Query: 1001 YHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKGYDG 1180 HRD+KPENLLL LK++DFG S + R T CGT Y+ PE+I +D Sbjct: 173 IHRDIKPENLLLGYRGELKIADFGWSVHAPSLR----RRTMCGTLDYLPPEMIEGHSHD- 227 Query: 1181 AKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXXXDPN 1360 K D+WS GV+ + + G PF+ + YK+I K + + P S + Sbjct: 228 EKVDLWSIGVLCYECLVGNPPFETASHAETYKRITKVDLQFPKLVSEGARDLISKLLRHS 287 Query: 1361 PSTRISIEKIMEHPWFR 1411 PS R+ + +MEHPW + Sbjct: 288 PSMRLPLRSVMEHPWVK 304
>Q6DE87:CHK1_XENLA Serine/threonine-protein kinase Chk1 - Xenopus laevis (African clawed| frog) Length = 474 Score = 173 bits (439), Expect = 2e-42 Identities = 96/267 (35%), Positives = 150/267 (56%), Gaps = 8/267 (2%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 +++ + LG+G + +V A N +T ++VA+K+ D + + IK+EI + +++ H N Sbjct: 9 WDLVQTLGEGAYGEVQLAVNRKTEEAVAVKIVDMTRA--ADCPENIKKEICINRMLSHTN 66 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNKVQRG-RLKEDAARKYFQQLICAVDFCHSRGV 1000 IV+ Y Y LE+ +GGELF++++ + E A+K+FQQLI V++ HS G+ Sbjct: 67 IVRFYGHRREGNIQYLFLEYCRGGELFDRIEPDVGMPEQDAQKFFQQLIAGVEYLHSIGI 126 Query: 1001 YHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKGYDG 1180 HRD+KPENLLLDE LK+SDFGL+T+ + LL+ CGT YVAPE+I + + Sbjct: 127 THRDIKPENLLLDERDQLKISDFGLATVFRHNGKERLLNKMCGTLPYVAPELIKSRAFHA 186 Query: 1181 AKADIWSCGVILFVLMAGYLPFQDKN-LMNMYKKIGKAEFKCPSW--FSSDXXXXXXXXX 1351 D+WSCG++L ++AG LP+ N + Y + W S+ Sbjct: 187 DPVDVWSCGIVLTAMLAGELPWDQPNEVCQEYCDWKEKNHYLTPWKKISATPLALLCKML 246 Query: 1352 DPNPSTRISIEKIMEHPWF----RKGL 1420 NP +RI+I I + WF +KGL Sbjct: 247 TENPQSRITIPDIKKDRWFTEIIKKGL 273
>O14965:STK6_HUMAN Serine/threonine-protein kinase 6 - Homo sapiens (Human)| Length = 403 Score = 173 bits (438), Expect = 3e-42 Identities = 87/258 (33%), Positives = 143/258 (55%), Gaps = 1/258 (0%) Frame = +2 Query: 635 MHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVK 814 + +E+G+ LG+G F VY AR ++ +A+KV K ++ K G+ Q++RE+ + ++ Sbjct: 130 LEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR 189 Query: 815 HPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQR-GRLKEDAARKYFQQLICAVDFCHS 991 HPNI+++Y T++Y +LE+ G ++ ++Q+ + E Y +L A+ +CHS Sbjct: 190 HPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHS 249 Query: 992 RGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKG 1171 + V HRD+KPENLLL LK++DFG S + R T CGT Y+ PE+I + Sbjct: 250 KRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRT----TLCGTLDYLPPEMIEGRM 305 Query: 1172 YDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXXX 1351 +D K D+WS GV+ + + G PF+ YK+I + EF P + + Sbjct: 306 HD-EKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLL 364 Query: 1352 DPNPSTRISIEKIMEHPW 1405 NPS R + +++EHPW Sbjct: 365 KHNPSQRPMLREVLEHPW 382
>P25323:MYLK_DICDI Myosin light chain kinase - Dictyostelium discoideum (Slime mold)| Length = 295 Score = 173 bits (438), Expect = 3e-42 Identities = 98/264 (37%), Positives = 151/264 (57%), Gaps = 8/264 (3%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 YE + LG+G F+ VY N +T Q AIKV +K ++ K +K E+ ++K V HPN Sbjct: 8 YEFKEELGRGAFSIVYLGENKQTKQRYAIKVINKSELGKD-YEKNLKMEVDILKKVNHPN 66 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNK-VQRGRLKEDAARKYFQQLICAVDFCHSRGV 1000 I+ + E+ T K+Y V+E V GGELF+K V++G E A ++++ AV + H + Sbjct: 67 IIALKELFDTPEKLYLVMELVTGGELFDKIVEKGSYSEADAANLVKKIVSAVGYLHGLNI 126 Query: 1001 YHRDLKPENLLLDENSN---LKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKG 1171 HRDLKPENLLL N + ++DFGLS I ++ T+CGTP+YVAPEV+N G Sbjct: 127 VHRDLKPENLLLKSKENHLEVAIADFGLSKIIGQTL---VMQTACGTPSYVAPEVLNATG 183 Query: 1172 YDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPS--W--FSSDXXXXX 1339 YD + D+WS GVI ++L+ G+ PF + ++++I +A ++ P W S + Sbjct: 184 YD-KEVDMWSIGVITYILLCGFPPFYGDTVPEIFEQIMEANYEFPEEYWGGISKEAKDFI 242 Query: 1340 XXXXDPNPSTRISIEKIMEHPWFR 1411 + S R++ + HPW + Sbjct: 243 GKLLVVDVSKRLNATNALNHPWLK 266
>O15075:DCLK1_HUMAN Serine/threonine-protein kinase DCLK1 - Homo sapiens (Human)| Length = 740 Score = 172 bits (437), Expect = 4e-42 Identities = 99/269 (36%), Positives = 150/269 (55%), Gaps = 11/269 (4%) Frame = +2 Query: 632 LMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLV 811 + +Y++G+ +G G FA V T++ A+K+ K K G I+ E+S+++ V Sbjct: 386 ITERYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCR--GKEHMIQNEVSILRRV 443 Query: 812 KHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKV-QRGRLKEDAARKYFQQLICAVDFCH 988 KHPNIV + E M T++Y V+E VKGG+LF+ + + E A L A+ + H Sbjct: 444 KHPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLH 503 Query: 989 SRGVYHRDLKPENLLL----DENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEV 1156 S + HRD+KPENLL+ D + +LK+ DFGL+TI +DG L+T CGTP YVAPE+ Sbjct: 504 SLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATI-----VDGPLYTVCGTPTYVAPEI 558 Query: 1157 INRKGYDGAKADIWSCGVILFVLMAGYLPFQ----DKNLMNMYKKIGKAEFKCPSW--FS 1318 I GY G K DIW+ GVI ++L+ G+ PF+ D+ ++ +G+ +F P W S Sbjct: 559 IAETGY-GLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVS 617 Query: 1319 SDXXXXXXXXXDPNPSTRISIEKIMEHPW 1405 + R S +++EHPW Sbjct: 618 DSAKELITMMLLVDVDQRFSAVQVLEHPW 646
>P59241:STK6_RAT Serine/threonine-protein kinase 6 - Rattus norvegicus (Rat)| Length = 397 Score = 172 bits (436), Expect = 5e-42 Identities = 85/260 (32%), Positives = 145/260 (55%), Gaps = 1/260 (0%) Frame = +2 Query: 635 MHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVK 814 + +++G+ LG+G F VY AR ++ +A+KV K ++ K G+ Q++RE+ + ++ Sbjct: 123 LEDFDIGRPLGKGKFGNVYLAREKQSKFILALKVLFKVQLEKAGVEHQLRREVEIQSHLR 182 Query: 815 HPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQR-GRLKEDAARKYFQQLICAVDFCHS 991 HPNI+++Y T++Y +LE+ G ++ ++Q+ + E Y +L A+ +CHS Sbjct: 183 HPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHS 242 Query: 992 RGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKG 1171 + V HRD+KPENLLL N LK++DFG S + R T CGT Y PE+I + Sbjct: 243 KRVIHRDIKPENLLLGSNGELKIADFGWSVHAPSSRRT----TLCGTLDYQPPEMIEGRM 298 Query: 1172 YDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXXX 1351 +D K D+WS GV+ + + G PF+ Y++I + EF P + + Sbjct: 299 HD-EKVDLWSLGVLCYEFLVGMPPFEAHTYQETYRRISRVEFTFPDFVTEGARDLISRLL 357 Query: 1352 DPNPSTRISIEKIMEHPWFR 1411 N S R+++ +++EHPW + Sbjct: 358 KHNSSQRLTLAEVLEHPWIK 377
>Q8BWQ5:DCLK3_MOUSE Serine/threonine-protein kinase DCLK3 - Mus musculus (Mouse)| Length = 619 Score = 172 bits (436), Expect = 5e-42 Identities = 94/265 (35%), Positives = 158/265 (59%), Gaps = 11/265 (4%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 Y++G ++G G FA V R+ ET Q+ A+K+ DK ++ G D + EI +++ + HPN Sbjct: 343 YDIGGVIGDGNFATVKECRHRETKQAYAMKMIDKSQLK--GKEDIVDSEILIIQSLSHPN 400 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNK-VQRGRLKEDAARKYFQQLICAVDFCHSRGV 1000 IV+++EV T+ +IY ++E+V+GG+LF+ V+ + E A L A+ H + + Sbjct: 401 IVKLHEVYETEAEIYLIMEYVQGGDLFDAIVENVKFPEPEAAVMITDLCKALVHMHDKNI 460 Query: 1001 YHRDLKPENLLLDENSN----LKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRK 1168 HRD+KPENLL+ N + LK++DFGL+ + + + T CGTP YVAPE+++ K Sbjct: 461 VHRDVKPENLLVQRNEDKSITLKLADFGLA-----KYVVRPIFTVCGTPTYVAPEILSEK 515 Query: 1169 GYDGAKADIWSCGVILFVLMAGYLPF----QDKNLMNMYKKIGKAEFKCPSW--FSSDXX 1330 GY G + D+W+ GVIL++L+ G+ PF +D++ + ++G+ EF P W S Sbjct: 516 GY-GLEVDMWAAGVILYILLCGFPPFRSPERDQDELFNIIQVGQFEFLSPYWDNISDAAK 574 Query: 1331 XXXXXXXDPNPSTRISIEKIMEHPW 1405 + +P R + E++++HPW Sbjct: 575 DLVRNLLEVDPKKRYTAEQVLQHPW 599
>Q91ZN7:CHK1_RAT Serine/threonine-protein kinase Chk1 - Rattus norvegicus (Rat)| Length = 476 Score = 172 bits (436), Expect = 5e-42 Identities = 95/275 (34%), Positives = 150/275 (54%), Gaps = 15/275 (5%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 +++ + LG+G + +V A N T ++VA+K+ D ++ + + IK+EI + K++ H N Sbjct: 9 WDLVQTLGEGAYGEVQLAVNRITEEAVAVKIVDMKRAID--CPENIKKEICINKMLNHEN 66 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNKVQRG-RLKEDAARKYFQQLICAVDFCHSRGV 1000 +V+ Y Y LE+ GGELF++++ + E A+++F QL+ V + H G+ Sbjct: 67 VVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEQDAQRFFHQLMAGVVYLHGIGI 126 Query: 1001 YHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKGYDG 1180 HRD+KPENLLLDE NLK+SDFGL+T+ + LL+ CGT YVAPE++ RK + Sbjct: 127 THRDIKPENLLLDERDNLKISDFGLATVFRHNNRERLLNKMCGTLPYVAPELLKRKEFHA 186 Query: 1181 AKADIWSCGVILFVLMAGYLPF--------------QDKNLMNMYKKIGKAEFKCPSWFS 1318 D+WSCG++L ++AG LP+ + K +N +KKI A Sbjct: 187 EPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPL------- 239 Query: 1319 SDXXXXXXXXXDPNPSTRISIEKIMEHPWFRKGLD 1423 NPS RI+I I + W+ K L+ Sbjct: 240 ----ALLHKILVENPSARITIPDIKKDRWYNKPLN 270
>Q8AYC9:CHK1_CHICK Serine/threonine-protein kinase Chk1 - Gallus gallus (Chicken)| Length = 476 Score = 172 bits (436), Expect = 5e-42 Identities = 94/263 (35%), Positives = 148/263 (56%), Gaps = 4/263 (1%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 +++ + LG+G + +V A N T ++VA+K+ D ++ + IK+EI + K++ H N Sbjct: 9 WDLVQTLGEGAYGEVQLAVNRRTEEAVAVKIVDMKRA--ADCPENIKKEICINKMLNHEN 66 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNKVQRG-RLKEDAARKYFQQLICAVDFCHSRGV 1000 +V+ Y Y LE+ GGELF++++ + E A+++FQQLI V + HS G+ Sbjct: 67 VVKFYGHRREGATQYLFLEYCSGGELFDRIEPDIGMPEPEAQRFFQQLIAGVVYLHSMGI 126 Query: 1001 YHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKGYDG 1180 HRDLKPENLLLDE NLK+SDFGL+T+ + + LL+ CGT YVAPE++ R + Sbjct: 127 THRDLKPENLLLDERDNLKISDFGLATVFKHNGRERLLNKMCGTLPYVAPELLRRPEFRA 186 Query: 1181 AKADIWSCGVILFVLMAGYLPF-QDKNLMNMYKKIGKAEFKCPSW--FSSDXXXXXXXXX 1351 D+W+CGV+L ++AG LP+ Q + Y + + W S Sbjct: 187 EPVDVWACGVVLTAMLAGELPWDQPSDSCQEYSDWKERKTYLAPWRKIDSAPLALLHKIL 246 Query: 1352 DPNPSTRISIEKIMEHPWFRKGL 1420 NP+ RI+I I + W+ + L Sbjct: 247 TENPTARITIPDIKKDRWYCRPL 269
>Q6DE08:AUKBA_XENLA Serine/threonine-protein kinase 12-A - Xenopus laevis (African clawed| frog) Length = 361 Score = 172 bits (436), Expect = 5e-42 Identities = 94/295 (31%), Positives = 153/295 (51%), Gaps = 1/295 (0%) Frame = +2 Query: 530 PQVPLQAPGIAAAFFCVRLPACLPAIMGEQKGNILMHKYEMGKMLGQGTFAKVYHARNIE 709 P PG A +P+ A+ K + +++G+ LG+G F VY AR + Sbjct: 57 PSASSSVPGRVAV--STEMPSQNTALAEMPKRKFTIDDFDIGRPLGKGKFGNVYLAREKQ 114 Query: 710 TSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPNIVQMYEVMATKTKIYFVLEHVK 889 +A+KV K ++ K G+ Q++REI + ++HPNI++MY + +IY +LE Sbjct: 115 NKFIMALKVLFKSQLEKEGVEHQLRREIEIQSHLRHPNILRMYNYFHDRKRIYLMLEFAP 174 Query: 890 GGELFNKVQR-GRLKEDAARKYFQQLICAVDFCHSRGVYHRDLKPENLLLDENSNLKVSD 1066 GEL+ ++Q+ GR E + + ++L A+ +CH R V HRD+KPENLL+ LK++D Sbjct: 175 RGELYKELQKHGRFDEQRSATFMEELADALHYCHERKVIHRDIKPENLLMGYKGELKIAD 234 Query: 1067 FGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKGYDGAKADIWSCGVILFVLMAGYLPF 1246 FG S + R T CGT Y+ PE+I K +D K D+W GV+ + + G PF Sbjct: 235 FGWSVHAPSLR----RRTMCGTLDYLPPEMIEGKTHD-EKVDLWCAGVLCYEFLVGMPPF 289 Query: 1247 QDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXXXDPNPSTRISIEKIMEHPWFR 1411 + +++I + K P + S +P R+ ++ +MEHPW + Sbjct: 290 DSPSHTETHRRIVNVDLKFPPFLSDGSKDLISKLLRYHPPQRLPLKGVMEHPWVK 344
>O01427:AIR2_CAEEL Aurora/Ipl1-related protein kinase 2 - Caenorhabditis elegans| Length = 305 Score = 172 bits (436), Expect = 5e-42 Identities = 90/274 (32%), Positives = 145/274 (52%), Gaps = 1/274 (0%) Frame = +2 Query: 614 EQKGNILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREI 793 ++ G ++ +E+G+ LG+G F VY AR VAIKV K +++ GG+ Q++REI Sbjct: 20 QKGGKFTINDFEIGRPLGKGKFGSVYLARTKTGHFHVAIKVLFKSQLISGGVEHQLEREI 79 Query: 794 SVMKLVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQ-RGRLKEDAARKYFQQLIC 970 + + HPNI+++Y KIY VLE+ GGE++ ++ R E A KY ++ Sbjct: 80 EIQSHLNHPNIIKLYTYFWDAKKIYLVLEYAPGGEMYKQLTVSKRFSEPTAAKYMYEIAD 139 Query: 971 AVDFCHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAP 1150 A+ +CH + V HRD+KPENLL+ LK+ DFG S + + T CGT Y+ P Sbjct: 140 ALSYCHRKNVIHRDIKPENLLIGSQGELKIGDFGWSVHAPSNK----RQTMCGTMDYLPP 195 Query: 1151 EVINRKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXX 1330 E++N + A D+W+ GV+ + + G PF+ ++ Y I A F P Sbjct: 196 EMVNGADHSDA-VDLWAIGVLCYEFLVGKPPFEHEDQSKTYAAIKAARFTYPDSVKKGAR 254 Query: 1331 XXXXXXXDPNPSTRISIEKIMEHPWFRKGLDAKL 1432 +P R ++E++ EH W + ++AK+ Sbjct: 255 DLIGRLLVVDPKARCTLEQVKEHYWIQGMMEAKI 288
>Q61241:TSSK1_MOUSE Testis-specific serine/threonine-protein kinase 1 - Mus musculus| (Mouse) Length = 364 Score = 172 bits (435), Expect = 7e-42 Identities = 99/261 (37%), Positives = 148/261 (56%), Gaps = 7/261 (2%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 Y MG LG+G++AKV A + +VA+K+ D++K L + REI ++ ++ H + Sbjct: 12 YIMGINLGEGSYAKVKSAYSERLKFNVAVKIIDRKKAPSDFLEKFLPREIEILAMLNHRS 71 Query: 824 IVQMYEVMATKT-KIYFVLEHVKGGELFNKVQ-RGRLKEDAARKYFQQLICAVDFCHSRG 997 IV+ YE+ AT K+Y V+E G+L ++ RG L+ED ARK F QL A+ +CH Sbjct: 72 IVKTYEIFATSDGKVYIVMELGVQGDLLEFIKTRGALQEDDARKKFHQLSSAIKYCHDLD 131 Query: 998 VYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDG----LLHTSCGTPAYVAPEVINR 1165 V HRDLK ENLLLD++ N+K+SDFG S C R D L T CG+ AY APEV+ Sbjct: 132 VVHRDLKSENLLLDKDFNIKLSDFGFS--KRCLRDDSGRLILSKTFCGSAAYAAPEVLQG 189 Query: 1166 KGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNM-YKKIGKAEFKCPSWFSSDXXXXXX 1342 Y DIWS GVIL++++ G +P+ D N+ + +K + F + + Sbjct: 190 IPYQPKVYDIWSLGVILYIMVCGSMPYDDSNIKKLRIQKEHRVNFPRSKHLTGECKDLIY 249 Query: 1343 XXXDPNPSTRISIEKIMEHPW 1405 P+ + R+ I++I+ H W Sbjct: 250 RMLQPDVNRRLHIDEILNHCW 270
>P97477:STK6_MOUSE Serine/threonine-protein kinase 6 - Mus musculus (Mouse)| Length = 395 Score = 172 bits (435), Expect = 7e-42 Identities = 84/260 (32%), Positives = 145/260 (55%), Gaps = 1/260 (0%) Frame = +2 Query: 635 MHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVK 814 + +++G+ LG+G F VY AR ++ +A+KV K ++ K + Q++RE+ + ++ Sbjct: 121 LEDFDIGRPLGKGKFGNVYLARERQSKFILALKVLFKTQLEKANVEHQLRREVEIQSHLR 180 Query: 815 HPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQR-GRLKEDAARKYFQQLICAVDFCHS 991 HPNI+++Y T++Y +LE+ G ++ ++Q+ + E Y +L A+ +CHS Sbjct: 181 HPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHS 240 Query: 992 RGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKG 1171 + V HRD+KPENLLL N LK++DFG S + R T CGT Y+ PE+I + Sbjct: 241 KRVIHRDIKPENLLLGSNGELKIADFGWSVHAPSSRRT----TMCGTLDYLPPEMIEGRM 296 Query: 1172 YDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXXX 1351 +D K D+WS GV+ + + G PF+ Y++I + EF P + + Sbjct: 297 HD-EKVDLWSLGVLCYEFLVGMPPFEAHTYQETYRRISRVEFTFPDFVTEGARDLISRLL 355 Query: 1352 DPNPSTRISIEKIMEHPWFR 1411 N S R+++ +++EHPW + Sbjct: 356 KHNASQRLTLAEVLEHPWIK 375
>P07334:CDR1_SCHPO Mitosis inducer protein kinase cdr1 - Schizosaccharomyces pombe| (Fission yeast) Length = 593 Score = 172 bits (435), Expect = 7e-42 Identities = 97/256 (37%), Positives = 145/256 (56%), Gaps = 2/256 (0%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 + +GK LG G+ + V A++ +T AIK+ I EI +M+L++HPN Sbjct: 12 WRLGKTLGTGSTSCVRLAKHAKTGDLAAIKIIPIRYA-------SIGMEILMMRLLRHPN 64 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNKVQR-GRLKEDAARKYFQQLICAVDFCHSRGV 1000 I+++Y+V +Y LE+V GELF+ +++ G L E A Y Q++ AV CH Sbjct: 65 ILRLYDVWTDHQHMYLALEYVPDGELFHYIRKHGPLSEREAAHYLSQILDAVAHCHRFRF 124 Query: 1001 YHRDLKPENLLLDENSN-LKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKGYD 1177 HRDLK EN+L+ N +K++DFG++T+ D L CG+ Y+APE+++ K Y Sbjct: 125 RHRDLKLENILIKVNEQQIKIADFGMATVEPN---DSCLENYCGSLHYLAPEIVSHKPYR 181 Query: 1178 GAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXXXDP 1357 GA AD+WSCGVIL+ L++ LPF +N +Y KI + PS SS D Sbjct: 182 GAPADVWSCGVILYSLLSNKLPFGGQNTDVIYNKIRHGAYDLPSSISSAAQDLLHRMLDV 241 Query: 1358 NPSTRISIEKIMEHPW 1405 NPSTRI+I ++ HP+ Sbjct: 242 NPSTRITIPEVFSHPF 257
>Q755C4:IPL1_ASHGO Spindle assembly checkpoint kinase - Ashbya gossypii (Yeast)| (Eremothecium gossypii) Length = 367 Score = 171 bits (433), Expect = 1e-41 Identities = 81/264 (30%), Positives = 152/264 (57%), Gaps = 1/264 (0%) Frame = +2 Query: 626 NILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMK 805 N+ + +E+GK+LG+G F +VY R+IE+ A+K +K+ +++ + Q +RE+ + Sbjct: 103 NLKLADFEIGKVLGKGKFGRVYCVRHIESGFVCALKAMEKKDIIQYNIEKQFRREVEIQS 162 Query: 806 LVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQ-RGRLKEDAARKYFQQLICAVDF 982 ++HPN+ Q+Y + ++Y ++E++ GEL+ ++ R + A Y Q+ A+D+ Sbjct: 163 SLRHPNLTQLYGYFHDEKRVYLLMEYLVNGELYKHLKGRSHFNDVVASYYVYQMADALDY 222 Query: 983 CHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVIN 1162 H R + HRD+KPEN+++ N+ +K++DFG S I+ T CGT Y++PE+I Sbjct: 223 MHERNILHRDIKPENIIIGFNNTIKLTDFGWSVITP---KGSKRKTLCGTVDYLSPELIR 279 Query: 1163 RKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXX 1342 + Y+ K D+W+ GV+ + L+ G PF++++ YK+I K P ++ Sbjct: 280 SREYN-EKVDVWALGVLTYELLVGSPPFEEESKELTYKRILKRNLIFPDHVDTEARHLIS 338 Query: 1343 XXXDPNPSTRISIEKIMEHPWFRK 1414 + +P RI ++++ +HPW K Sbjct: 339 RLLEYDPGDRIPLKEVKKHPWIEK 362
>Q6GPL3:AUKBB_XENLA Serine/threonine-protein kinase 12-B - Xenopus laevis (African clawed| frog) Length = 368 Score = 171 bits (433), Expect = 1e-41 Identities = 89/271 (32%), Positives = 147/271 (54%), Gaps = 1/271 (0%) Frame = +2 Query: 602 AIMGEQKGNILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQI 781 A+ K + +++G+ LG+G F VY AR + +A+KV K ++ K G+ Q+ Sbjct: 86 ALAEAPKRKFTIDDFDIGRPLGKGKFGNVYLAREKQNKFIMALKVLFKSQLEKEGVEHQL 145 Query: 782 KREISVMKLVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQR-GRLKEDAARKYFQ 958 +REI + ++HPNI++MY + +IY +LE GEL+ ++Q+ GR E + + + Sbjct: 146 RREIEIQSHLRHPNILRMYNYFHDRKRIYLMLEFAPRGELYKELQKHGRFDEQRSATFME 205 Query: 959 QLICAVDFCHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPA 1138 +L A+ +CH R V HRD+KPENLL+ LK++DFG S + R T CGT Sbjct: 206 ELADALQYCHERKVIHRDIKPENLLMGYKGELKIADFGWSVHAPSLR----RRTMCGTLD 261 Query: 1139 YVAPEVINRKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFS 1318 Y+ PE+I K +D K D+W GV+ + + G PF + +++I + K P + S Sbjct: 262 YLPPEMIEGKTHD-EKVDLWCAGVLCYEFLVGMPPFDSPSHSETHRRIVNVDLKFPPFLS 320 Query: 1319 SDXXXXXXXXXDPNPSTRISIEKIMEHPWFR 1411 +P+ R+ ++ +MEHPW + Sbjct: 321 EGSKDLISKLLRYHPAQRLPLKGVMEHPWVK 351
>Q2TA06:STK6_BOVIN Serine/threonine-protein kinase 6 - Bos taurus (Bovine)| Length = 402 Score = 171 bits (432), Expect = 2e-41 Identities = 86/258 (33%), Positives = 143/258 (55%), Gaps = 1/258 (0%) Frame = +2 Query: 635 MHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVK 814 + +E+G+ LG+G F VY AR ++ +A+KV K ++ K G+ Q++RE+ + ++ Sbjct: 130 LEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR 189 Query: 815 HPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQR-GRLKEDAARKYFQQLICAVDFCHS 991 HPNI+++Y T++Y +LE+ G ++ ++Q+ + E Y +L A+ +CHS Sbjct: 190 HPNILRLYGYFHDATRVYLILEYAPLGAVYRELQKLSKFDEQRTATYITELANALSYCHS 249 Query: 992 RGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKG 1171 + V HRD+KPENLLL LK++DFG S + R T CGT Y+ PE+I + Sbjct: 250 KRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRT----TLCGTLDYLPPEMIEGRM 305 Query: 1172 YDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXXX 1351 +D K D+WS GV+ + + G PF+ Y++I + EF P Sbjct: 306 HD-EKVDLWSLGVLCYEFLVGKPPFEADTYQETYRRISRVEFTFPDCVPEGARDLISRLL 364 Query: 1352 DPNPSTRISIEKIMEHPW 1405 NPS R ++++++EHPW Sbjct: 365 KHNPSQRPTLKEVLEHPW 382
>O14757:CHK1_HUMAN Serine/threonine-protein kinase Chk1 - Homo sapiens (Human)| Length = 476 Score = 171 bits (432), Expect = 2e-41 Identities = 94/274 (34%), Positives = 149/274 (54%), Gaps = 15/274 (5%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 +++ + LG+G + +V A N T ++VA+K+ D ++ + + IK+EI + K++ H N Sbjct: 9 WDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVD--CPENIKKEICINKMLNHEN 66 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNKVQRG-RLKEDAARKYFQQLICAVDFCHSRGV 1000 +V+ Y Y LE+ GGELF++++ + E A+++F QL+ V + H G+ Sbjct: 67 VVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGI 126 Query: 1001 YHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKGYDG 1180 HRD+KPENLLLDE NLK+SDFGL+T+ + LL+ CGT YVAPE++ R+ + Sbjct: 127 THRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRREFHA 186 Query: 1181 AKADIWSCGVILFVLMAGYLPF--------------QDKNLMNMYKKIGKAEFKCPSWFS 1318 D+WSCG++L ++AG LP+ + K +N +KKI A Sbjct: 187 EPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPL------- 239 Query: 1319 SDXXXXXXXXXDPNPSTRISIEKIMEHPWFRKGL 1420 NPS RI+I I + W+ K L Sbjct: 240 ----ALLHKILVENPSARITIPDIKKDRWYNKPL 269
>O55099:AURKB_RAT Serine/threonine-protein kinase 12 - Rattus norvegicus (Rat)| Length = 343 Score = 171 bits (432), Expect = 2e-41 Identities = 94/272 (34%), Positives = 147/272 (54%), Gaps = 2/272 (0%) Frame = +2 Query: 602 AIMGEQKGN-ILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQ 778 A+ G Q + +E+G+ LG+G F VY AR ++ VA+K+ K ++ K G+ Q Sbjct: 65 ALQGSQSRQPFTIDNFEIGRPLGKGKFGNVYLAREKKSRFIVALKILFKSQIEKEGVEHQ 124 Query: 779 IKREISVMKLVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQR-GRLKEDAARKYF 955 ++REI + +KHPNI+Q+Y + +IY +LE+ GEL+ ++Q+ G E Sbjct: 125 LRREIEIQAHLKHPNILQLYNYFYDQQRIYLILEYAPRGELYKELQKSGTFDEQRTATIM 184 Query: 956 QQLICAVDFCHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTP 1135 ++L A+ +CH + V HRD+KPENLLL LK++DFG S + R T CGT Sbjct: 185 EELSDALMYCHKKKVIHRDIKPENLLLGLQGELKIADFGWSVHAPSLR----RKTMCGTL 240 Query: 1136 AYVAPEVINRKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWF 1315 Y+ PE+I + ++ D+W GV+ + LM G PF+ + Y++I K + K PS Sbjct: 241 DYLPPEMIEGRMHN-EMVDLWCIGVLCYELMVGNPPFESPSHSETYRRIVKVDLKFPSSM 299 Query: 1316 SSDXXXXXXXXXDPNPSTRISIEKIMEHPWFR 1411 NPS R+ +E++ HPW R Sbjct: 300 PLGAKDLISKLLKHNPSQRLPLEQVSAHPWVR 331
>Q9HFF4:PPK1_SCHPO Serine/threonine-protein kinase ppk1 - Schizosaccharomyces pombe| (Fission yeast) Length = 1023 Score = 170 bits (431), Expect = 2e-41 Identities = 106/292 (36%), Positives = 154/292 (52%), Gaps = 30/292 (10%) Frame = +2 Query: 626 NILMHKYEMGKMLGQGTFAKVYHARNIETSQS--------VAIKVTDKEKVLKGGLTDQI 781 N Y +G+ +G G F KV + + S V IK+ K + T ++ Sbjct: 486 NYTFGSYILGRTIGTGEFGKVKLGWPLPKANSTIHRSTPQVVIKIVLSTK--QNCQTSRL 543 Query: 782 KREISVMKLV--KHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKV-QRGRLKEDAARKY 952 RE++++K + HP+IV+ + + TK VL++V GGELF+ + R RL++ A + Sbjct: 544 MREVAILKGLGNNHPHIVKYLDFVKTKHHFGIVLDYVNGGELFDYILARRRLEDSVACRL 603 Query: 953 FQQLICAVDFCHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTI----------SECRRL 1102 F QLI V + HSRGV HRDLK EN+LLD N N+ ++DFG +T S Sbjct: 604 FAQLISGVAYLHSRGVVHRDLKLENILLDTNRNIVIADFGFATTFGHFNTLSEHSLPTEK 663 Query: 1103 DGLLHTSCGTPAYVAPEVINRKG--YDGAKADIWSCGVILFVLMAGYLPFQD-------K 1255 L TSCG+P Y APE++N K Y G +ADIWSCGVIL+ ++AGYLPF D + Sbjct: 664 PDLFSTSCGSPCYAAPELVNCKSGMYAGTQADIWSCGVILYAMLAGYLPFDDDPHNPNGE 723 Query: 1256 NLMNMYKKIGKAEFKCPSWFSSDXXXXXXXXXDPNPSTRISIEKIMEHPWFR 1411 N+ +Y+ I P +F S P+P+ R+ + IM H + R Sbjct: 724 NVPRLYRYICSTPLIFPEFFKSKARDILKKILVPDPAKRVRMSAIMNHAYLR 775
>P42818:KPK1_ARATH Serine/threonine-protein kinase AtPK1/AtPK6 - Arabidopsis thaliana| (Mouse-ear cress) Length = 465 Score = 170 bits (431), Expect = 2e-41 Identities = 97/288 (33%), Positives = 163/288 (56%), Gaps = 6/288 (2%) Frame = +2 Query: 623 GNILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVM 802 G + + +E+ K++G+G F KVY R ETS+ A+KV K+ +++ + +K E ++ Sbjct: 127 GVVGIDDFEVMKVVGKGAFGKVYQVRKKETSEIYAMKVMRKDHIMEKNHAEYMKAERDIL 186 Query: 803 KLVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKV-QRGRLKEDAARKYFQQLICAVD 979 + HP IVQ+ TK ++Y VL+ + GG LF ++ +G +ED AR Y +++ AV Sbjct: 187 TKIDHPFIVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSAVS 246 Query: 980 FCHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVI 1159 H +G+ HRDLKPEN+L+D + ++ ++DFGL+ E ++ CGT Y+APE++ Sbjct: 247 HLHEKGIMHRDLKPENILMDTDGHVMLTDFGLAKEFEENTRS---NSMCGTTEYMAPEIV 303 Query: 1160 NRKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXX 1339 KG+D A AD WS G++L+ ++ G PF + +KI K + K P + S++ Sbjct: 304 RGKGHDKA-ADWWSVGILLYEMLTGKPPFLGSK-GKIQQKIVKDKIKLPQFLSNEAHAIL 361 Query: 1340 XXXXDPNPSTRI-----SIEKIMEHPWFRKGLDAKLLRYNLQAKDAVP 1468 P R+ E+I +H WF KG++ K L+A++ +P Sbjct: 362 KGLLQKEPERRLGSGLSGAEEIKQHKWF-KGINWK----KLEAREVMP 404
>P28178:PK2_DICDI Protein kinase 2 - Dictyostelium discoideum (Slime mold)| Length = 479 Score = 170 bits (430), Expect = 3e-41 Identities = 94/292 (32%), Positives = 157/292 (53%), Gaps = 8/292 (2%) Frame = +2 Query: 605 IMGEQKGNILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIK 784 I + K + +E+ ++G+G+F KV + + A+KV K+ ++ + K Sbjct: 140 IFSKNKQSATKDDFELLNVIGKGSFGKVMQVKKKGEDKIFAMKVLRKDAIIARKQVNHTK 199 Query: 785 REISVMKLVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQR-GRLKEDAARKYFQQ 961 E ++++ + HP IV ++ TK K+Y VL+ V GGELF ++R GR E + Y + Sbjct: 200 SEKTILQCISHPFIVNLHYAFQTKDKLYMVLDFVNGGELFFHLKREGRFSEPRVKIYAAE 259 Query: 962 LICAVDFCHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAY 1141 ++ A+D H + + +RDLKPEN+LLD ++ ++DFGLS + DG T CGTP Y Sbjct: 260 IVSALDHLHKQDIVYRDLKPENILLDSEGHICITDFGLS--KKIETTDGTF-TFCGTPEY 316 Query: 1142 VAPEVINRKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSS 1321 +APEV+N G+ G D WS G +L+ ++ G PF +N+ MY+KI E K P++ S Sbjct: 317 LAPEVLNGHGH-GCAVDWWSLGTLLYEMLTGLPPFYSQNVSTMYQKILNGELKIPTYISP 375 Query: 1322 DXXXXXXXXXDPNPSTRISIE---KIMEHPWFR----KGLDAKLLRYNLQAK 1456 + R+ + ++ +HPWF+ + LD K + + + K Sbjct: 376 EAKSLLEGLLTREVDKRLGTKGGGEVKQHPWFKNIDWEKLDRKEVEVHFKPK 427
>Q8BHI9:NIM1_MOUSE Serine/threonine-protein kinase NIM1 - Mus musculus (Mouse)| Length = 436 Score = 170 bits (430), Expect = 3e-41 Identities = 92/257 (35%), Positives = 141/257 (54%), Gaps = 1/257 (0%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 Y + +G G F++V + T + VAIK+ DK K L + REIS M+ + HPN Sbjct: 74 YRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTK-LDQKTQRLLSREISSMEKLHHPN 132 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNKVQ-RGRLKEDAARKYFQQLICAVDFCHSRGV 1000 IV++YEV+ T +K++ V+E+ GGELF K+ G+L E ++ F Q++ AV H + Sbjct: 133 IVRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQILSAVKHMHENQI 192 Query: 1001 YHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKGYDG 1180 HRDLK EN+ + +KV DFG ST+S + +L+T CG+P Y APE+ + Y G Sbjct: 193 IHRDLKAENVFYTSRTCVKVGDFGFSTVS---KKGEMLNTFCGSPPYAAPELFRDQHYVG 249 Query: 1181 AKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXXXDPN 1360 DIW+ GV+L+ ++ G +PF+ + + + K I + + P S P Sbjct: 250 VYVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYTIPQHVSEPCHRLIRGVLQPT 309 Query: 1361 PSTRISIEKIMEHPWFR 1411 P+ R I IM + W R Sbjct: 310 PTERYGINYIMSNEWMR 326
>P22987:KIN1_SCHPO Protein kinase kin1 - Schizosaccharomyces pombe (Fission yeast)| Length = 891 Score = 170 bits (430), Expect = 3e-41 Identities = 90/273 (32%), Positives = 151/273 (55%), Gaps = 19/273 (6%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDK-------------EKVLKGGLTDQIK 784 Y +GK +G G+ KV A +++T + AIK+ + + K +++ K Sbjct: 125 YVLGKTIGAGSMGKVKVAHHLKTGEQFAIKIVTRLHPDITKAKAAASAEATKAAQSEKNK 184 Query: 785 -----REISVMKLVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKV-QRGRLKEDAAR 946 RE ++ L++HP I + +V T + Y V E V GG++ + + G+LKE AR Sbjct: 185 EIRTVREAALSTLLRHPYICEARDVYITNSHYYMVFEFVDGGQMLDYIISHGKLKEKQAR 244 Query: 947 KYFQQLICAVDFCHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSC 1126 K+ +Q+ A+ + H V HRDLK EN+L+ + ++K+ DFGLS + R L T C Sbjct: 245 KFVRQIGSALSYLHQNSVVHRDLKIENILISKTGDIKIIDFGLSNLY---RRQSRLRTFC 301 Query: 1127 GTPAYVAPEVINRKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCP 1306 G+ + APE++N + Y G + D+WS G++L+VL+ G +PF D+N+ ++ KI K + P Sbjct: 302 GSLYFAAPELLNAQPYIGPEVDVWSFGIVLYVLVCGKVPFDDQNMSALHAKIKKGTVEYP 361 Query: 1307 SWFSSDXXXXXXXXXDPNPSTRISIEKIMEHPW 1405 S+ SSD +P R ++E+++ HPW Sbjct: 362 SYLSSDCKGLLSRMLVTDPLKRATLEEVLNHPW 394
>Q3SZW1:TSSK1_BOVIN Testis-specific serine/threonine-protein kinase 1 - Bos taurus| (Bovine) Length = 367 Score = 169 bits (429), Expect = 3e-41 Identities = 98/262 (37%), Positives = 147/262 (56%), Gaps = 8/262 (3%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 Y MG LG+G++AKV A + +VA+K+ D++K L + REI ++ ++ H + Sbjct: 12 YIMGINLGEGSYAKVKSAYSERLKFNVAVKIIDRKKAPTDFLEKFLPREIEILAMLNHRS 71 Query: 824 IVQMYEVMATKT-KIYFVLEHVKGGELFNKVQ-RGRLKEDAARKYFQQLICAVDFCHSRG 997 I++ YE+ T K+Y V+E G+L ++ RG L+ED ARK F QL A+ +CH Sbjct: 72 IIKTYEIFETSDGKVYIVMELGVQGDLLEFIKTRGALQEDDARKKFHQLSSAIKYCHDLD 131 Query: 998 VYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDG----LLHTSCGTPAYVAPEVINR 1165 V HRDLK ENLLLD++ N+K+SDFG S C R D L T CG+ AY APEV+ Sbjct: 132 VVHRDLKCENLLLDKDFNIKLSDFGFS--KRCLRDDSGRLTLSKTFCGSAAYAAPEVLQG 189 Query: 1166 KGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYK--KIGKAEFKCPSWFSSDXXXXX 1339 Y DIWS GVIL++++ G +P+ D N+ M + K + F + + Sbjct: 190 IPYQPKVYDIWSLGVILYIMVCGSMPYDDSNIKKMLRIQKEHRVNFPRSKHLTGECKDLI 249 Query: 1340 XXXXDPNPSTRISIEKIMEHPW 1405 P+ + R+ I++I+ H W Sbjct: 250 YRMLQPDVTRRLHIDEILSHCW 271
>Q39030:KPK19_ARATH Serine/threonine-protein kinase AtPK19 - Arabidopsis thaliana| (Mouse-ear cress) Length = 471 Score = 169 bits (429), Expect = 3e-41 Identities = 93/272 (34%), Positives = 154/272 (56%), Gaps = 6/272 (2%) Frame = +2 Query: 614 EQKGNILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREI 793 E G + + +E+ K++GQG F KVY R +TS+ A+KV K+K+++ + +K E Sbjct: 130 EVSGVVGIEDFEVLKVVGQGAFGKVYQVRKKDTSEIYAMKVMRKDKIVEKNHAEYMKAER 189 Query: 794 SVMKLVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKV-QRGRLKEDAARKYFQQLIC 970 ++ + HP IVQ+ TK ++Y VL+ + GG LF ++ +G +ED AR Y +++ Sbjct: 190 DILTKIDHPFIVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVS 249 Query: 971 AVDFCHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAP 1150 AV H +G+ HRDLKPEN+L+D + ++ ++DFGL+ E ++ CGT Y+AP Sbjct: 250 AVSHLHEKGIMHRDLKPENILMDVDGHVMLTDFGLAKEFEENTRS---NSMCGTTEYMAP 306 Query: 1151 EVINRKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXX 1330 E++ KG+D A AD WS G++L+ ++ G PF + +KI K + K P + S++ Sbjct: 307 EIVRGKGHDKA-ADWWSVGILLYEMLTGKPPFLGSK-GKIQQKIVKDKIKLPQFLSNEAH 364 Query: 1331 XXXXXXXDPNPSTRI-----SIEKIMEHPWFR 1411 P R+ E+I +H WF+ Sbjct: 365 ALLKGLLQKEPERRLGSGPSGAEEIKKHKWFK 396
>Q9BXA7:TSSK1_HUMAN Testis-specific serine/threonine-protein kinase 1 - Homo sapiens| (Human) Length = 367 Score = 169 bits (428), Expect = 4e-41 Identities = 97/264 (36%), Positives = 147/264 (55%), Gaps = 8/264 (3%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 Y +G LG+G++AKV A + +VAIK+ D++K L + REI ++ ++ H + Sbjct: 12 YLLGINLGEGSYAKVKSAYSERLKFNVAIKIIDRKKAPADFLEKFLPREIEILAMLNHCS 71 Query: 824 IVQMYEVMATKT-KIYFVLEHVKGGELFNKVQ-RGRLKEDAARKYFQQLICAVDFCHSRG 997 I++ YE+ T K+Y V+E G+L ++ RG L ED ARK F QL A+ +CH Sbjct: 72 IIKTYEIFETSHGKVYIVMELAVQGDLLELIKTRGALHEDEARKKFHQLSLAIKYCHDLD 131 Query: 998 VYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLD----GLLHTSCGTPAYVAPEVINR 1165 V HRDLK +NLLLD++ N+K+SDF S C R D L T CG+PAY APEV+ Sbjct: 132 VVHRDLKCDNLLLDKDFNIKLSDFSFS--KRCLRDDSGRMALSKTFCGSPAYAAPEVLQG 189 Query: 1166 KGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYK--KIGKAEFKCPSWFSSDXXXXX 1339 Y DIWS GVIL++++ G +P+ D N+ M + K + F + + Sbjct: 190 IPYQPKVYDIWSLGVILYIMVCGSMPYDDSNIKKMLRIQKEHRVNFPRSKHLTGECKDLI 249 Query: 1340 XXXXDPNPSTRISIEKIMEHPWFR 1411 P+ + R+ I++I+ H W + Sbjct: 250 YHMLQPDVNRRLHIDEILSHCWMQ 273
>Q8BW96:KCC1D_MOUSE Calcium/calmodulin-dependent protein kinase type 1D - Mus musculus| (Mouse) Length = 385 Score = 169 bits (428), Expect = 4e-41 Identities = 102/265 (38%), Positives = 152/265 (57%), Gaps = 11/265 (4%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 +E + LG G F++V A T + A+K K K LKG I+ EI+V++ +KH N Sbjct: 23 FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPK-KALKGK-ESSIENEIAVLRKIKHEN 80 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNK-VQRGRLKEDAARKYFQQLICAVDFCHSRGV 1000 IV + ++ + +Y V++ V GGELF++ V++G E A +Q++ AV + H G+ Sbjct: 81 IVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGI 140 Query: 1001 YHRDLKPENLLL---DENSNLKVSDFGLSTISECRRLDG---LLHTSCGTPAYVAPEVIN 1162 HRDLKPENLL DE S + +SDFGLS +++G ++ T+CGTP YVAPEV+ Sbjct: 141 VHRDLKPENLLYYSQDEESKIMISDFGLS------KMEGKGDVMSTACGTPGYVAPEVLA 194 Query: 1163 RKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKA--EFKCPSW--FSSDXX 1330 +K Y A D WS GVI ++L+ GY PF D+N ++++I KA EF P W S Sbjct: 195 QKPYSKA-VDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAK 253 Query: 1331 XXXXXXXDPNPSTRISIEKIMEHPW 1405 + +P+ R + E+ HPW Sbjct: 254 DFIRNLMEKDPNKRYTCEQAARHPW 278
>Q8IU85:KCC1D_HUMAN Calcium/calmodulin-dependent protein kinase type 1D - Homo sapiens| (Human) Length = 385 Score = 169 bits (428), Expect = 4e-41 Identities = 102/265 (38%), Positives = 152/265 (57%), Gaps = 11/265 (4%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 +E + LG G F++V A T + A+K K K LKG I+ EI+V++ +KH N Sbjct: 23 FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPK-KALKGK-ESSIENEIAVLRKIKHEN 80 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNK-VQRGRLKEDAARKYFQQLICAVDFCHSRGV 1000 IV + ++ + +Y V++ V GGELF++ V++G E A +Q++ AV + H G+ Sbjct: 81 IVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGI 140 Query: 1001 YHRDLKPENLLL---DENSNLKVSDFGLSTISECRRLDG---LLHTSCGTPAYVAPEVIN 1162 HRDLKPENLL DE S + +SDFGLS +++G ++ T+CGTP YVAPEV+ Sbjct: 141 VHRDLKPENLLYYSQDEESKIMISDFGLS------KMEGKGDVMSTACGTPGYVAPEVLA 194 Query: 1163 RKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKA--EFKCPSW--FSSDXX 1330 +K Y A D WS GVI ++L+ GY PF D+N ++++I KA EF P W S Sbjct: 195 QKPYSKA-VDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAK 253 Query: 1331 XXXXXXXDPNPSTRISIEKIMEHPW 1405 + +P+ R + E+ HPW Sbjct: 254 DFIRNLMEKDPNKRYTCEQAARHPW 278
>O35280:CHK1_MOUSE Serine/threonine-protein kinase Chk1 - Mus musculus (Mouse)| Length = 476 Score = 169 bits (428), Expect = 4e-41 Identities = 94/275 (34%), Positives = 149/275 (54%), Gaps = 15/275 (5%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 +++ + LG+G + +V A N T ++VA+K+ D ++ + + IK+EI + K++ H N Sbjct: 9 WDLVQTLGEGAYGEVQLAVNRITEEAVAVKIVDMKRAID--CPENIKKEICINKMLSHEN 66 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNKVQRG-RLKEDAARKYFQQLICAVDFCHSRGV 1000 +V+ Y Y LE+ GGELF++++ + E A+++F QL+ V + H G+ Sbjct: 67 VVKFYGHRREGHIQYLFLEYCSGGELFDRIEPDIGMPEQDAQRFFHQLMAGVVYLHGIGI 126 Query: 1001 YHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKGYDG 1180 HRD+KPENLLLDE NLK+SDFGL+T+ + LL+ CGT YVAPE++ RK + Sbjct: 127 THRDIKPENLLLDERDNLKISDFGLATVFRHNNRERLLNKMCGTLPYVAPELLKRKEFHA 186 Query: 1181 AKADIWSCGVILFVLMAGYLPF--------------QDKNLMNMYKKIGKAEFKCPSWFS 1318 D+WSCG++L ++AG LP+ + K +N +KKI A Sbjct: 187 EPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPL------- 239 Query: 1319 SDXXXXXXXXXDPNPSTRISIEKIMEHPWFRKGLD 1423 PS RI+I I + W+ K L+ Sbjct: 240 ----ALLHKILVETPSARITIPDIKKDRWYNKPLN 270
>Q61XD3:AIR2_CAEBR Aurora/Ipl1-related protein kinase 2 - Caenorhabditis briggsae| Length = 302 Score = 169 bits (428), Expect = 4e-41 Identities = 87/269 (32%), Positives = 143/269 (53%), Gaps = 1/269 (0%) Frame = +2 Query: 623 GNILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVM 802 G + ++ +E+G+ LG+G F VY AR AIKV K +++ GG+ Q++REI + Sbjct: 20 GKLSINDFEIGRPLGKGKFGSVYLARTKTGHFHCAIKVLFKSQLISGGVEHQLEREIEIQ 79 Query: 803 KLVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKV-QRGRLKEDAARKYFQQLICAVD 979 ++HPNI+++Y KIY +LE+ GGE++ ++ + R E A KY ++ A+ Sbjct: 80 SHLQHPNIIRLYNYFWDAKKIYLILEYAPGGEMYKQLTTQKRFTEAMAGKYMYEIADALS 139 Query: 980 FCHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVI 1159 +CH + V HRD+KPENLL+ LK+ DFG S + + T CGT Y+ PE++ Sbjct: 140 YCHRKNVIHRDIKPENLLIGAQGELKIGDFGWSVHAPSNK----RQTMCGTMDYLPPEMV 195 Query: 1160 NRKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXX 1339 N + A D+W+ GV+ + + G PF+ +N + Y I F P + Sbjct: 196 NGNSHSDA-VDLWAIGVLCYEFLVGKPPFEHENQADTYSAIKAGRFTYPDFVKKGARDLI 254 Query: 1340 XXXXDPNPSTRISIEKIMEHPWFRKGLDA 1426 +P R S++++ +H W LD+ Sbjct: 255 GKLLVVDPRRRCSLQEVKDHYWVTSMLDS 283
>P05986:KAPC_YEAST cAMP-dependent protein kinase type 3 - Saccharomyces cerevisiae| (Baker's yeast) Length = 398 Score = 168 bits (426), Expect = 7e-41 Identities = 85/280 (30%), Positives = 157/280 (56%), Gaps = 6/280 (2%) Frame = +2 Query: 614 EQKGNILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREI 793 + G + +++ + LG G+F +V+ R+ + A+K K ++K + E Sbjct: 78 DTSGKYSLSDFQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDER 137 Query: 794 SVMKLVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQRGRLKEDAARKYFQQLIC- 970 ++ +V HP I++M+ +++ V+++++GGELF+ +++ + + K++ +C Sbjct: 138 RMLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCL 197 Query: 971 AVDFCHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAP 1150 A+++ HS+ + +RDLKPEN+LLD+N ++K++DFG + + + + +T CGTP Y+AP Sbjct: 198 ALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFA-----KYVPDVTYTLCGTPDYIAP 252 Query: 1151 EVINRKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXX 1330 EV++ K Y+ D WS GV+++ ++AGY PF + N M Y+ I AE K P +F D Sbjct: 253 EVVSTKPYN-KSVDWWSFGVLIYEMLAGYTPFYNSNTMKTYENILNAELKFPPFFHPDAQ 311 Query: 1331 XXXXXXXDPNPSTRI-----SIEKIMEHPWFRKGLDAKLL 1435 + S R+ E + HPWF + + KLL Sbjct: 312 DLLKKLITRDLSERLGNLQNGSEDVKNHPWFNEVIWEKLL 351
>O70126:AURKB_MOUSE Serine/threonine-protein kinase 12 - Mus musculus (Mouse)| Length = 345 Score = 168 bits (426), Expect = 7e-41 Identities = 91/267 (34%), Positives = 144/267 (53%), Gaps = 1/267 (0%) Frame = +2 Query: 614 EQKGNILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREI 793 + K + +E+G+ LG+G F VY AR ++ VA+K+ K ++ K G+ Q++REI Sbjct: 72 QNKQPFTIDNFEIGRPLGKGKFGNVYLAREKKSRFIVALKILFKSQIEKEGVEHQLRREI 131 Query: 794 SVMKLVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQRGR-LKEDAARKYFQQLIC 970 + +KHPNI+Q+Y + +IY +LE+ GEL+ ++Q+ R E ++L Sbjct: 132 EIQAHLKHPNILQLYNYFYDQQRIYLILEYAPRGELYKELQKSRTFDEQRTATIMEELSD 191 Query: 971 AVDFCHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAP 1150 A+ +CH + V HRD+KPENLLL LK++DFG S + R T CGT Y+ P Sbjct: 192 ALTYCHKKKVIHRDIKPENLLLGLQGELKIADFGWSVHAPSLR----RKTMCGTLDYLPP 247 Query: 1151 EVINRKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXX 1330 E+I + ++ D+W GV+ + LM G PF+ + Y++I K + K PS S Sbjct: 248 EMIEGRMHN-EMVDLWCIGVLCYELMVGNPPFESPSHSETYRRIVKVDLKFPSSVPSGAQ 306 Query: 1331 XXXXXXXDPNPSTRISIEKIMEHPWFR 1411 NP R+ + ++ HPW R Sbjct: 307 DLISKLLKHNPWQRLPLAEVAAHPWVR 333
>Q9N0X0:AURKB_PIG Serine/threonine-protein kinase 12 - Sus scrofa (Pig)| Length = 344 Score = 168 bits (425), Expect = 1e-40 Identities = 89/257 (34%), Positives = 143/257 (55%), Gaps = 1/257 (0%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 +E+G+ LG+G F VY AR ++ VA+KV K ++ K G+ Q++REI + ++HPN Sbjct: 77 FEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLQHPN 136 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNKVQRGR-LKEDAARKYFQQLICAVDFCHSRGV 1000 I+++Y + +IY +LE+ GEL+ ++Q+ R E ++L A+ +CH + V Sbjct: 137 ILRLYNYFYDRRRIYLILEYAPRGELYKELQKCRTFDEQRTATIMEELADALIYCHGKKV 196 Query: 1001 YHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKGYDG 1180 HRD+KPENLLL LK++DFG S + R T CGT Y+ PE+I + ++ Sbjct: 197 IHRDIKPENLLLGLQGELKIADFGWSVHAPSLR----RKTMCGTLDYLPPEMIEGRTHN- 251 Query: 1181 AKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXXXDPN 1360 K D+W GV+ + L+ G PF+ + Y++IGK + K P + N Sbjct: 252 EKVDLWCIGVLCYELLVGNPPFESASHNETYRRIGKVDLKFPPSVPAGAQDLISKLLKHN 311 Query: 1361 PSTRISIEKIMEHPWFR 1411 PS R+ + ++ HPW R Sbjct: 312 PSDRLPLAQVSAHPWVR 328
>Q924X7:STK33_MOUSE Serine/threonine-protein kinase 33 - Mus musculus (Mouse)| Length = 491 Score = 167 bits (423), Expect = 2e-40 Identities = 97/268 (36%), Positives = 153/268 (57%), Gaps = 14/268 (5%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 Y G++LGQG+F V+ A + ET AIK +KEK + ++RE+S++K V H + Sbjct: 111 YTFGRILGQGSFGMVFEAIDKETGAKWAIKKVNKEKAGSSAMK-LLEREVSILKTVNHQH 169 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNKV-QRGRLKEDAARKYFQQLICAVDFCHSRGV 1000 I+ + +V + K+Y V+E + GEL + QRG E+ R Q L A+ + H++ + Sbjct: 170 IIHLEQVFESPQKMYLVMELCEDGELKAVMDQRGHFSENETRLIIQSLASAIAYLHNKDI 229 Query: 1001 YHRDLKPENLL-----LDENS----NLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPE 1153 HRDLK EN++ +D+N+ N+KV+DFGLS R +G++ T+CGTP Y+APE Sbjct: 230 VHRDLKLENIMVKSSFIDDNNEMNLNIKVTDFGLSVQKHGSRSEGMMQTTCGTPIYMAPE 289 Query: 1154 VINRKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAE--FKCPSW--FSS 1321 VIN Y + DIWS GVI+F+L+ G PF + +Y+ I K E F+ P W S Sbjct: 290 VINAHDY-SQQCDIWSIGVIMFILLCGEPPFLANSEEKLYELIKKGELRFENPVWESVSD 348 Query: 1322 DXXXXXXXXXDPNPSTRISIEKIMEHPW 1405 +P+ RI+ ++++++ W Sbjct: 349 SAKNTLKQLMKVDPAHRITAKELLDNQW 376
>Q9D2E1:TSSK3_MOUSE Testis-specific serine/threonine-protein kinase 3 - Mus musculus| (Mouse) Length = 268 Score = 167 bits (422), Expect = 2e-40 Identities = 94/262 (35%), Positives = 155/262 (59%), Gaps = 3/262 (1%) Frame = +2 Query: 629 ILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKL 808 +L + Y++GK +G+GT++KV A + + + VAIK+ DK + + + RE+ +++ Sbjct: 5 LLSNGYQLGKTIGEGTYSKVKEAFSKKHQRKVAIKIIDKMGGPEEFIQRFLPRELQIVRT 64 Query: 809 VKHPNIVQMYEVMATKT-KIYFVLEHVKGGELFNKVQRGR-LKEDAARKYFQQLICAVDF 982 + H NI+Q+YE++ + KIY V+E +GG++F+ V G L E A+ F+Q++ A+ + Sbjct: 65 LDHKNIIQVYEMLESADGKIYLVMELAEGGDVFDCVLNGGPLPESRAKALFRQMVEAIRY 124 Query: 983 CHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVIN 1162 CH GV HRDLK EN LL + NLK++DFG + + R + L T CG+ AY APEV+ Sbjct: 125 CHGCGVAHRDLKCENALL-QGFNLKLTDFGFAKVLPKSRRE-LSQTFCGSTAYAAPEVLQ 182 Query: 1163 RKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNM-YKKIGKAEFKCPSWFSSDXXXXX 1339 +D K D+WS GV+L+V++ LPF D ++ M +++ F S++ Sbjct: 183 GIPHDSKKGDVWSMGVVLYVMLCASLPFDDTDIPKMLWQQQKGVSFPTHLGISTECQDLL 242 Query: 1340 XXXXDPNPSTRISIEKIMEHPW 1405 +P+ R SIE++ HPW Sbjct: 243 KRLLEPDMILRPSIEEVSWHPW 264
>P38991:IPL1_YEAST Spindle assembly checkpoint kinase - Saccharomyces cerevisiae| (Baker's yeast) Length = 367 Score = 167 bits (422), Expect = 2e-40 Identities = 86/263 (32%), Positives = 146/263 (55%), Gaps = 3/263 (1%) Frame = +2 Query: 626 NILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMK 805 ++ + +E+GK LG+G F KVY R+ T A+KV +KE+++K L Q +RE+ + Sbjct: 98 SLSLDDFELGKKLGKGKFGKVYCVRHRSTGYICALKVMEKEEIIKYNLQKQFRREVEIQT 157 Query: 806 LVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQ-RGRLKEDAARKYFQQLICAVDF 982 + HPN+ + Y + ++Y ++E++ GE++ ++ G + A Y Q+ A+D+ Sbjct: 158 SLNHPNLTKSYGYFHDEKRVYLLMEYLVNGEMYKLLRLHGPFNDILASDYIYQIANALDY 217 Query: 983 CHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTIS--ECRRLDGLLHTSCGTPAYVAPEV 1156 H + + HRD+KPEN+L+ N+ +K++DFG S I+ E RR T CGT Y++PE+ Sbjct: 218 MHKKNIIHRDIKPENILIGFNNVIKLTDFGWSIINPPENRR-----KTVCGTIDYLSPEM 272 Query: 1157 INRKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXX 1336 + + YD D W+ GV+ F L+ G PF+++ YK+I + K PS S D Sbjct: 273 VESREYDHT-IDAWALGVLAFELLTGAPPFEEEMKDTTYKRIAALDIKMPSNISQDAQDL 331 Query: 1337 XXXXXDPNPSTRISIEKIMEHPW 1405 +P R+ + + HPW Sbjct: 332 ILKLLKYDPKDRMRLGDVKMHPW 354
>Q9WTK7:STK11_MOUSE Serine/threonine-protein kinase 11 - Mus musculus (Mouse)| Length = 436 Score = 166 bits (421), Expect = 3e-40 Identities = 92/268 (34%), Positives = 150/268 (55%), Gaps = 7/268 (2%) Frame = +2 Query: 632 LMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKV--LKGGLTDQIKREISVMK 805 L+ KY MG +LG+G++ KV + ET A+K+ K+K+ + G + +K+EI +++ Sbjct: 45 LIGKYLMGDLLGEGSYGKVKEVLDSETLCRRAVKILKKKKLRRIPNGEAN-VKKEIQLLR 103 Query: 806 LVKHPNIVQMYEVMAT--KTKIYFVLEHVKGG--ELFNKVQRGRLKEDAARKYFQQLICA 973 ++H N++Q+ +V+ K K+Y V+E+ G E+ + V R A YF+QLI Sbjct: 104 RLRHRNVIQLVDVLYNEEKQKMYMVMEYCVCGMQEMLDSVPEKRFPVCQAHGYFRQLIDG 163 Query: 974 VDFCHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPE 1153 +++ HS+G+ H+D+KP NLLL N LK+SD G++ +D TS G+PA+ PE Sbjct: 164 LEYLHSQGIVHKDIKPGNLLLTTNGTLKISDLGVAEALHPFAVDDTCRTSQGSPAFQPPE 223 Query: 1154 VIN-RKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXX 1330 + N + G K DIWS GV L+ + G PF+ N+ +++ IG+ +F P Sbjct: 224 IANGLDTFSGFKVDIWSAGVTLYNITTGLYPFEGDNIYKLFENIGRGDFTIPCDCGPPLS 283 Query: 1331 XXXXXXXDPNPSTRISIEKIMEHPWFRK 1414 + P+ R SI +I +H WFRK Sbjct: 284 DLLRGMLEYEPAKRFSIRQIRQHSWFRK 311
>Q7YRC6:AURKB_BOVIN Serine/threonine-protein kinase 12 - Bos taurus (Bovine)| Length = 344 Score = 166 bits (421), Expect = 3e-40 Identities = 89/265 (33%), Positives = 145/265 (54%), Gaps = 1/265 (0%) Frame = +2 Query: 620 KGNILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISV 799 K + + +E+G+ LG+G F VY AR ++ VA+KV K ++ K G+ Q++REI + Sbjct: 69 KRSFTIDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEI 128 Query: 800 MKLVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQRGR-LKEDAARKYFQQLICAV 976 ++HPNI+++Y + +IY +LE+ GEL+ ++Q+ R E ++L A+ Sbjct: 129 QAHLQHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSRTFDEQRTATIMEELADAL 188 Query: 977 DFCHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEV 1156 +CH++ V HRD+KPENLLL LK++DFG S + R T CGT Y+ PE+ Sbjct: 189 TYCHAKKVIHRDIKPENLLLGLRGELKIADFGWSVHAPSLR----RKTMCGTLDYLPPEM 244 Query: 1157 INRKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXX 1336 I + ++ K D+W GV+ + L+ G PF+ + Y++I K + K P Sbjct: 245 IEGRTHN-EKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPPSVPLGAQDF 303 Query: 1337 XXXXXDPNPSTRISIEKIMEHPWFR 1411 NPS R+ + ++ HPW R Sbjct: 304 IYKLLKHNPSERLPLAQVSAHPWVR 328
>Q0GGW5:STK11_CHICK Serine/threonine protein kinase 11 - Gallus gallus (Chicken)| Length = 440 Score = 166 bits (419), Expect = 5e-40 Identities = 93/268 (34%), Positives = 150/268 (55%), Gaps = 7/268 (2%) Frame = +2 Query: 632 LMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKV--LKGGLTDQIKREISVMK 805 L+ KY MG +LG+G++ KV + ET A+K+ K+K+ + G + +K+EI +++ Sbjct: 45 LIGKYLMGDLLGEGSYGKVKEMLDSETLCRRAVKILKKKKLRRIPNGEAN-VKKEIQLLR 103 Query: 806 LVKHPNIVQMYEVMAT--KTKIYFVLEHVKGG--ELFNKVQRGRLKEDAARKYFQQLICA 973 ++H N++Q+ +V+ K K+Y V+E+ G E+ + V R A YF QLI Sbjct: 104 RLRHKNVIQLVDVLYNEEKQKMYMVMEYCVCGMQEMLDSVPEKRFPVFQAHGYFCQLIDG 163 Query: 974 VDFCHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPE 1153 +++ HS+G+ H+D+KP NLLL N LK+SD G++ D TS G+PA+ PE Sbjct: 164 LEYLHSQGIVHKDIKPGNLLLTTNGTLKISDLGVAEALHPFAEDDTCRTSQGSPAFQPPE 223 Query: 1154 VIN-RKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXX 1330 + N + G K DIWS GV L+ + G PF+ N+ +++ IGK +F P Sbjct: 224 IANGLDTFSGFKVDIWSAGVTLYNITTGLYPFEGDNIYKLFENIGKGDFTIPEDCGPPLS 283 Query: 1331 XXXXXXXDPNPSTRISIEKIMEHPWFRK 1414 + +P+ R SI++I +H WFRK Sbjct: 284 DLLRGMLEYDPAKRFSIQQIRQHNWFRK 311
>Q8IY84:NIM1_HUMAN Serine/threonine-protein kinase NIM1 - Homo sapiens (Human)| Length = 436 Score = 166 bits (419), Expect = 5e-40 Identities = 90/257 (35%), Positives = 141/257 (54%), Gaps = 1/257 (0%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 Y + +G G F++V + T + VAIK+ DK K L + REIS M+ + HPN Sbjct: 74 YRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTK-LDQKTQRLLSREISSMEKLHHPN 132 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNKVQ-RGRLKEDAARKYFQQLICAVDFCHSRGV 1000 I+++YEV+ T +K++ V+E+ GGELF K+ G+L E ++ F Q++ AV H + Sbjct: 133 IIRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQIVSAVKHMHENQI 192 Query: 1001 YHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKGYDG 1180 HRDLK EN+ N+ +KV DFG ST+S + +L+T CG+P Y APE+ + Y G Sbjct: 193 IHRDLKAENVFYTSNTCVKVGDFGFSTVS---KKGEMLNTFCGSPPYAAPELFRDEHYIG 249 Query: 1181 AKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXXXDPN 1360 DIW+ GV+L+ ++ G +PF+ + + + K I + + P S Sbjct: 250 IYVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYSVPPHVSEPCHRLIRGVLQQI 309 Query: 1361 PSTRISIEKIMEHPWFR 1411 P+ R I+ IM W + Sbjct: 310 PTERYGIDCIMNDEWMQ 326
>O70150:KCC1B_RAT Calcium/calmodulin-dependent protein kinase type 1B - Rattus| norvegicus (Rat) Length = 343 Score = 166 bits (419), Expect = 5e-40 Identities = 98/262 (37%), Positives = 153/262 (58%), Gaps = 8/262 (3%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 YE+ + LG G F++V A+ ++ VA+K K K L+G ++ EI+V++ + HPN Sbjct: 15 YEIREKLGSGAFSEVMLAQERGSAHLVALKCIPK-KALRGKEA-LVENEIAVLRRISHPN 72 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNKV-QRGRLKEDAARKYFQQLICAVDFCHSRGV 1000 IV + +V + + +Y +E V GGELF+++ +RG E A Q++ AV + HS G+ Sbjct: 73 IVALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLHSLGI 132 Query: 1001 YHRDLKPENLLLD---ENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKG 1171 HRDLKPENLL E+S + VSDFGLS I + +L T+CGTP YVAPE++ +K Sbjct: 133 VHRDLKPENLLYATPFEDSKIMVSDFGLSKI----QAGNMLGTACGTPGYVAPELLEQKP 188 Query: 1172 YDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKA--EFKCPSW--FSSDXXXXX 1339 Y G D+W+ GVI ++L+ GY PF D++ ++ +I +A EF P W S Sbjct: 189 Y-GKAVDVWALGVISYILLCGYPPFYDESDPELFSQILRASYEFDSPFWDDISESAKDFI 247 Query: 1340 XXXXDPNPSTRISIEKIMEHPW 1405 + +P R + ++ ++H W Sbjct: 248 RHLLERDPQKRFTCQQALQHLW 269
>Q9QYK9:KCC1B_MOUSE Calcium/calmodulin-dependent protein kinase type 1B - Mus musculus| (Mouse) Length = 343 Score = 166 bits (419), Expect = 5e-40 Identities = 98/262 (37%), Positives = 153/262 (58%), Gaps = 8/262 (3%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 YE+ + LG G F++V A+ ++ VA+K K K L+G ++ EI+V++ + HPN Sbjct: 15 YEIREKLGSGAFSEVMLAQERGSAHLVALKCIPK-KALRGKEA-LVENEIAVLRRISHPN 72 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNKV-QRGRLKEDAARKYFQQLICAVDFCHSRGV 1000 IV + +V + + +Y +E V GGELF+++ +RG E A Q++ AV + HS G+ Sbjct: 73 IVALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLHSLGI 132 Query: 1001 YHRDLKPENLLLD---ENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKG 1171 HRDLKPENLL E+S + VSDFGLS I + +L T+CGTP YVAPE++ +K Sbjct: 133 VHRDLKPENLLYATPFEDSKIMVSDFGLSKI----QAGNMLGTACGTPGYVAPELLEQKP 188 Query: 1172 YDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKA--EFKCPSW--FSSDXXXXX 1339 Y G D+W+ GVI ++L+ GY PF D++ ++ +I +A EF P W S Sbjct: 189 Y-GKAVDVWALGVISYILLCGYPPFYDESDPELFSQILRASYEFDSPFWDDISESAKDFI 247 Query: 1340 XXXXDPNPSTRISIEKIMEHPW 1405 + +P R + ++ ++H W Sbjct: 248 RHLLERDPQKRFTCQQALQHLW 269
>Q9UQB9:AURKC_HUMAN Serine/threonine-protein kinase 13 - Homo sapiens (Human)| Length = 309 Score = 166 bits (419), Expect = 5e-40 Identities = 88/255 (34%), Positives = 141/255 (55%), Gaps = 1/255 (0%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 +E+G+ LG+G F VY AR E+ VA+KV K ++ K GL Q++REI + ++HPN Sbjct: 43 FEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHPN 102 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNKVQRG-RLKEDAARKYFQQLICAVDFCHSRGV 1000 I+++Y ++Y +LE+ GEL+ ++Q+ +L E ++L A+ +CH + V Sbjct: 103 ILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHDKKV 162 Query: 1001 YHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKGYDG 1180 HRD+KPENLLL +K++DFG S + R T CGT Y+ PE+I + YD Sbjct: 163 IHRDIKPENLLLGFRGEVKIADFGWSVHTPSLR----RKTMCGTLDYLPPEMIEGRTYD- 217 Query: 1181 AKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXXXDPN 1360 K D+W GV+ + L+ GY PF+ + Y++I K + + P Sbjct: 218 EKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGARDLISRLLRYQ 277 Query: 1361 PSTRISIEKIMEHPW 1405 P R+ + +I++HPW Sbjct: 278 PLERLPLAQILKHPW 292
>Q501V0:KPSH1_DANRE Serine/threonine-protein kinase H1 homolog - Danio rerio (Zebrafish)| (Brachydanio rerio) Length = 422 Score = 165 bits (418), Expect = 6e-40 Identities = 92/263 (34%), Positives = 157/263 (59%), Gaps = 8/263 (3%) Frame = +2 Query: 641 KYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHP 820 KY++ ++G+G+F++V + T Q AIK+ + + +G + + E+ V++ V+H Sbjct: 95 KYDIKALIGRGSFSRVVRVEHRSTRQPYAIKMIET-RYREG--REVCESELCVLRRVRHT 151 Query: 821 NIVQMYEVMATKTKIYFVLEHVKGGELFNK-VQRGRLKEDAARKYFQQLICAVDFCHSRG 997 NI+Q+ EV T ++Y V+E GGELF++ + RG E A + Q ++ V + H+ G Sbjct: 152 NIIQLMEVFETAERVYMVMELATGGELFDRIITRGSFTERDATRVLQMVLDGVKYLHTLG 211 Query: 998 VYHRDLKPENLLL---DENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRK 1168 + HRDLKPENLL +S + ++DFGL++ + + + L+ T+CGTP Y+APE++ RK Sbjct: 212 ITHRDLKPENLLYYHPGADSKIMITDFGLASTRK-KGDECLMKTTCGTPEYIAPEILVRK 270 Query: 1169 GYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKI--GKAEFKCPSW--FSSDXXXX 1336 Y A D+W+ GVI ++L++G +PF+D N M +Y++I GK F W S+ Sbjct: 271 PYTNA-VDMWALGVISYILLSGTMPFEDDNRMRLYRQILKGKYSFSGEPWPSVSNLAKDF 329 Query: 1337 XXXXXDPNPSTRISIEKIMEHPW 1405 +P+ R+S + ++HPW Sbjct: 330 IDRVLTVDPNERLSAGQALKHPW 352
>O61661:CHK1_DROME Serine/threonine-protein kinase grp - Drosophila melanogaster (Fruit| fly) Length = 512 Score = 165 bits (418), Expect = 6e-40 Identities = 87/261 (33%), Positives = 153/261 (58%), Gaps = 7/261 (2%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 + + + LG+G + +V N +T ++VA+K+ D +K + +++E+ + K+++ + Sbjct: 22 WTLAQTLGEGAYGEVKLLINRQTGEAVAMKMVDLKK--HPDAANSVRKEVCIQKMLQDKH 79 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNKVQRG-RLKEDAARKYFQQLICAVDFCHSRGV 1000 I++ + + + Y LE+ GGELF++++ + + A++YF QL+ +++ H RG+ Sbjct: 80 ILRFFGKRSQGSVEYIFLEYAAGGELFDRIEPDVGMPQHEAQRYFTQLLSGLNYLHQRGI 139 Query: 1001 YHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKGYDG 1180 HRDLKPENLLLDE+ N+K+SDFG++T+ C+ + LL CGT YVAPEV+ +K Y Sbjct: 140 AHRDLKPENLLLDEHDNVKISDFGMATMFRCKGKERLLDKRCGTLPYVAPEVL-QKAYHA 198 Query: 1181 AKADIWSCGVILFVLMAGYLPFQDKNL----MNMYKKIGKAEFKCPSWFSSD--XXXXXX 1342 AD+WSCGVIL ++AG LP+ + ++ + + P W D Sbjct: 199 QPADLWSCGVILVTMLAGELPWDQPSTNCTEFTNWRDNDHWQLQTP-WSKLDTLAISLLR 257 Query: 1343 XXXDPNPSTRISIEKIMEHPW 1405 +P TR+++EK ++H W Sbjct: 258 KLLATSPGTRLTLEKTLDHKW 278
>Q6P2M8:KCC1B_HUMAN Calcium/calmodulin-dependent protein kinase type 1B - Homo sapiens| (Human) Length = 343 Score = 165 bits (417), Expect = 8e-40 Identities = 98/262 (37%), Positives = 152/262 (58%), Gaps = 8/262 (3%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 YE+ + LG G F++V A+ ++ VA+K K K L+G ++ EI+V++ + HPN Sbjct: 15 YEIRERLGSGAFSEVVLAQERGSAHLVALKCIPK-KALRGKEA-LVENEIAVLRRISHPN 72 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNKV-QRGRLKEDAARKYFQQLICAVDFCHSRGV 1000 IV + +V + + +Y +E V GGELF+++ +RG E A Q++ AV + HS G+ Sbjct: 73 IVALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLHSLGI 132 Query: 1001 YHRDLKPENLLLD---ENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKG 1171 HRDLKPENLL E+S + VSDFGLS I + +L T+CGTP YVAPE++ +K Sbjct: 133 VHRDLKPENLLYATPFEDSKIMVSDFGLSKI----QAGNMLGTACGTPGYVAPELLEQKP 188 Query: 1172 YDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKA--EFKCPSW--FSSDXXXXX 1339 Y G D+W+ GVI ++L+ GY PF D++ ++ +I +A EF P W S Sbjct: 189 Y-GKAVDVWALGVISYILLCGYPPFYDESDPELFSQILRASYEFDSPFWDDISESAKDFI 247 Query: 1340 XXXXDPNPSTRISIEKIMEHPW 1405 + +P R + ++ + H W Sbjct: 248 RHLLERDPQKRFTCQQALRHLW 269
>P00517:KAPCA_BOVIN cAMP-dependent protein kinase, alpha-catalytic subunit - Bos taurus| (Bovine) Length = 351 Score = 164 bits (416), Expect = 1e-39 Identities = 91/264 (34%), Positives = 148/264 (56%), Gaps = 6/264 (2%) Frame = +2 Query: 635 MHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVK 814 + ++E K LG G+F +V +++ET A+K+ DK+KV+K + E +++ V Sbjct: 41 LDQFERIKTLGTGSFGRVMLVKHMETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVN 100 Query: 815 HPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQR-GRLKEDAARKYFQQLICAVDFCHS 991 P +V++ + +Y V+E+V GGE+F+ ++R GR E AR Y Q++ ++ HS Sbjct: 101 FPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHS 160 Query: 992 RGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKG 1171 + +RDLKPENLL+D+ ++V+DFG + +R+ G T CGTP Y+APE+I KG Sbjct: 161 LDLIYRDLKPENLLIDQQGYIQVTDFGFA-----KRVKGRTWTLCGTPEYLAPEIILSKG 215 Query: 1172 YDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXXX 1351 Y+ A D W+ GV+++ + AGY PF + +Y+KI + + PS FSSD Sbjct: 216 YNKA-VDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLL 274 Query: 1352 DPNPSTRI-----SIEKIMEHPWF 1408 + + R + I H WF Sbjct: 275 QVDLTKRFGNLKNGVNDIKNHKWF 298
>Q6CWQ4:IPL1_KLULA Spindle assembly checkpoint kinase - Kluyveromyces lactis (Yeast)| (Candida sphaerica) Length = 361 Score = 164 bits (415), Expect = 1e-39 Identities = 85/262 (32%), Positives = 148/262 (56%), Gaps = 2/262 (0%) Frame = +2 Query: 626 NILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMK 805 N+ + +E+GK+LG+G F KVY ++ ET A+K +K+++++ + Q +RE+ + Sbjct: 94 NMTLQDFEIGKILGKGKFGKVYCVKHRETGLICALKAMEKKEIVQYTIQKQFRREVEIQG 153 Query: 806 LVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQ-RGRLKEDAARKYFQQLICAVDF 982 KH N+ Q+Y + ++Y ++E+V GEL+ ++ G L E A + Q+ A+D+ Sbjct: 154 SFKHKNLTQLYGFFYDEKRVYLLMEYVYYGELYKFLKNNGPLNETLASYFVYQMANALDY 213 Query: 983 CHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLH-TSCGTPAYVAPEVI 1159 HS+ + HRD+KPEN+L+ N+ +K++DFG S +E DG T CGT Y++PE+I Sbjct: 214 MHSKNILHRDIKPENILIGFNNTIKLTDFGWSVYNE----DGQKRKTLCGTIDYLSPELI 269 Query: 1160 NRKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXX 1339 + Y+ K D+W+ GV+ + L+ G PF++ Y++I + + K P S Sbjct: 270 KSREYNN-KVDVWALGVLTYELLVGSPPFEEDTKEMTYRRILRCDLKFPLNVSPQARDLI 328 Query: 1340 XXXXDPNPSTRISIEKIMEHPW 1405 PS RI + ++ H W Sbjct: 329 VRLLQFEPSKRIPLSEVKSHAW 350
>Q9MZD9:KAPCA_SHEEP cAMP-dependent protein kinase, alpha-catalytic subunit - Ovis aries| (Sheep) Length = 351 Score = 164 bits (414), Expect = 2e-39 Identities = 91/264 (34%), Positives = 147/264 (55%), Gaps = 6/264 (2%) Frame = +2 Query: 635 MHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVK 814 + ++E K LG G+F +V ++ ET A+K+ DK+KV+K + E +++ V Sbjct: 41 LDQFERIKTLGTGSFGRVMLVKHTETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVN 100 Query: 815 HPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQR-GRLKEDAARKYFQQLICAVDFCHS 991 P +V++ + +Y V+E+V GGE+F+ ++R GR E AR Y Q++ ++ HS Sbjct: 101 FPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHS 160 Query: 992 RGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKG 1171 + +RDLKPENLL+D+ ++V+DFG + +R+ G T CGTP Y+APE+I KG Sbjct: 161 LDLIYRDLKPENLLIDQQGYIQVTDFGFA-----KRVKGRTWTLCGTPEYLAPEIILSKG 215 Query: 1172 YDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXXX 1351 Y+ A D W+ GV+++ + AGY PF + +Y+KI + + PS FSSD Sbjct: 216 YNKA-VDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLL 274 Query: 1352 DPNPSTRI-----SIEKIMEHPWF 1408 + + R + I H WF Sbjct: 275 QVDLTKRFGNLKNGVNDIKNHKWF 298
>Q15349:KS6A2_HUMAN Ribosomal protein S6 kinase alpha-2 - Homo sapiens (Human)| Length = 733 Score = 163 bits (413), Expect = 2e-39 Identities = 96/265 (36%), Positives = 153/265 (57%), Gaps = 9/265 (3%) Frame = +2 Query: 641 KYEMGKMLGQGTFAKVYHARNIETS---QSVAIKVTDKEKVLKGGLTDQIKREISVMKLV 811 ++E+ K+LGQG++ KV+ R ++ S Q A+KV K+ LK + K E ++ V Sbjct: 58 QFELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVL-KKATLKVRDRVRSKMERDILAEV 116 Query: 812 KHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQRGRL-KEDAARKYFQQLICAVDFCH 988 HP IV+++ T+ K+Y +L+ ++GG+LF ++ + + E+ + Y +L A+D H Sbjct: 117 NHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLH 176 Query: 989 SRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRK 1168 S G+ +RDLKPEN+LLDE ++K++DFGLS E D ++ CGT Y+APEV+NR+ Sbjct: 177 SLGIIYRDLKPENILLDEEGHIKITDFGLS--KEAIDHDKRAYSFCGTIEYMAPEVVNRR 234 Query: 1169 GYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXX 1348 G+ AD WS GV++F ++ G LPFQ K+ I KA+ P + S + Sbjct: 235 GHT-QSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLGMPQFLSGEAQSLLRAL 293 Query: 1349 XDPNPSTRI-----SIEKIMEHPWF 1408 NP R+ +E+I HP+F Sbjct: 294 FKRNPCNRLGAGIDGVEEIKRHPFF 318 Score = 131 bits (330), Expect = 1e-29 Identities = 82/266 (30%), Positives = 139/266 (52%), Gaps = 12/266 (4%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 YE+ + +G G+++ + T A+K+ DK K D + +++ +HPN Sbjct: 415 YEIKEDIGVGSYSVCKRCVHKATDTEYAVKIIDKSK------RDPSEEIEILLRYGQHPN 468 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNKVQRGR-LKEDAARKYFQQLICAVDFCHSRGV 1000 I+ + +V +Y V+E ++GGEL +++ R R E A + +D+ HS+GV Sbjct: 469 IITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQGV 528 Query: 1001 YHRDLKPENLLLDENS----NLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRK 1168 HRDLKP N+L + S +++V DFG + + R +GLL T C T +VAPEV+ R+ Sbjct: 529 VHRDLKPSNILYRDESGSPESIRVCDFGFA--KQLRAGNGLLMTPCYTANFVAPEVLKRQ 586 Query: 1169 GYDGAKADIWSCGVILFVLMAGYLPF---QDKNLMNMYKKIGKAEFKCP--SW--FSSDX 1327 GYD A DIWS G++L+ ++AG+ PF D + +IG ++ +W S Sbjct: 587 GYDAA-CDIWSLGILLYTMLAGFTPFANGPDDTPEEILARIGSGKYALSGGNWDSISDAA 645 Query: 1328 XXXXXXXXDPNPSTRISIEKIMEHPW 1405 +P R++ ++++HPW Sbjct: 646 KDVVSKMLHVDPHQRLTAMQVLKHPW 671
>P22694:KAPCB_HUMAN cAMP-dependent protein kinase, beta-catalytic subunit - Homo sapiens| (Human) Length = 351 Score = 163 bits (413), Expect = 2e-39 Identities = 92/269 (34%), Positives = 147/269 (54%), Gaps = 6/269 (2%) Frame = +2 Query: 620 KGNILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISV 799 + N + +E K LG G+F +V ++ T Q A+K+ DK+KV+K + E + Sbjct: 36 QNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRI 95 Query: 800 MKLVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQR-GRLKEDAARKYFQQLICAV 976 ++ V P +V++ + +Y V+E+V GGE+F+ ++R GR E AR Y Q++ Sbjct: 96 LQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTF 155 Query: 977 DFCHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEV 1156 ++ HS + +RDLKPENLL+D ++V+DFG + +R+ G T CGTP Y+APE+ Sbjct: 156 EYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFA-----KRVKGRTWTLCGTPEYLAPEI 210 Query: 1157 INRKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXX 1336 I KGY+ A D W+ GV+++ + AGY PF + +Y+KI + + PS FSSD Sbjct: 211 ILSKGYNKA-VDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDL 269 Query: 1337 XXXXXDPNPSTRI-----SIEKIMEHPWF 1408 + + R + I H WF Sbjct: 270 LRNLLQVDLTKRFGNLKNGVSDIKTHKWF 298
>P36887:KAPCA_PIG cAMP-dependent protein kinase, alpha-catalytic subunit - Sus scrofa| (Pig) Length = 351 Score = 163 bits (413), Expect = 2e-39 Identities = 91/264 (34%), Positives = 147/264 (55%), Gaps = 6/264 (2%) Frame = +2 Query: 635 MHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVK 814 + ++E K LG G+F +V ++ ET A+K+ DK+KV+K + E +++ V Sbjct: 41 LDQFERIKTLGTGSFGRVMLVKHKETGNHFAMKILDKQKVVKLKQIEHTLNEKRILQAVN 100 Query: 815 HPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQR-GRLKEDAARKYFQQLICAVDFCHS 991 P +V++ + +Y V+E+V GGE+F+ ++R GR E AR Y Q++ ++ HS Sbjct: 101 FPFLVKLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHS 160 Query: 992 RGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKG 1171 + +RDLKPENLL+D+ ++V+DFG + +R+ G T CGTP Y+APE+I KG Sbjct: 161 LDLIYRDLKPENLLIDQQGYIQVTDFGFA-----KRVKGRTWTLCGTPEYLAPEIILSKG 215 Query: 1172 YDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXXX 1351 Y+ A D W+ GV+++ + AGY PF + +Y+KI + + PS FSSD Sbjct: 216 YNKA-VDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLL 274 Query: 1352 DPNPSTRI-----SIEKIMEHPWF 1408 + + R + I H WF Sbjct: 275 QVDLTKRFGNLKNGVNDIKNHKWF 298
>Q6C3J2:IPL1_YARLI Spindle assembly checkpoint kinase - Yarrowia lipolytica (Candida| lipolytica) Length = 371 Score = 163 bits (413), Expect = 2e-39 Identities = 84/275 (30%), Positives = 153/275 (55%), Gaps = 2/275 (0%) Frame = +2 Query: 587 PACLPAIMGEQKGNILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGG 766 P+ L I G + N + +E+GK LG+G F KVY ++ +T A+K +K+++++G Sbjct: 82 PSPLTGITGFR--NYSLDDFEIGKALGKGKFGKVYLVKDKKTGFVSALKCMEKKELVEGN 139 Query: 767 LTDQIKREISVMKLVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQ-RGRLKEDAA 943 + Q +RE+ + ++H N+++++ K ++Y +LE+V GEL+ ++ + R E A Sbjct: 140 VEKQFRREVEIQSNLRHTNVLRLFGHFHDKDRVYLILEYVVHGELYKLLRNQKRFTESTA 199 Query: 944 RKYFQQLICAVDFCHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTS 1123 Y Q+ A+ + H + + HRD+KPEN+LL N +K+SDFG S + R T Sbjct: 200 SSYIYQMSEALLYLHGKNIIHRDIKPENILLHFNDTIKISDFGWSVHAPSNRRS----TL 255 Query: 1124 CGTPAYVAPEVINRKGYDGAKADIWSCGVILFVLMAGYLPFQDK-NLMNMYKKIGKAEFK 1300 CGT Y+ PE++ + YD D+WS G++++ + G PF++ Y++I K + + Sbjct: 256 CGTMDYLPPEIVQSRPYD-KNVDVWSLGILMYEFLCGAPPFEEPGGAQATYRRIVKLDLR 314 Query: 1301 CPSWFSSDXXXXXXXXXDPNPSTRISIEKIMEHPW 1405 P + S+D +P+ R ++ + +HPW Sbjct: 315 IPPYVSADAADLIKRMLTLDPAKRFKLKDMHKHPW 349
>Q96PN8:TSSK3_HUMAN Testis-specific serine/threonine-protein kinase 3 - Homo sapiens| (Human) Length = 268 Score = 163 bits (412), Expect = 3e-39 Identities = 94/262 (35%), Positives = 153/262 (58%), Gaps = 3/262 (1%) Frame = +2 Query: 629 ILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKL 808 +L + Y++GK +G+GT++KV A + + + VAIKV DK + + + RE+ +++ Sbjct: 5 LLSNGYQLGKTIGEGTYSKVKEAFSKKHQRKVAIKVIDKMGGPEEFIQRFLPRELQIVRT 64 Query: 809 VKHPNIVQMYEVMATKT-KIYFVLEHVKGGELFNKVQRGR-LKEDAARKYFQQLICAVDF 982 + H NI+Q+YE++ + KI V+E +GG++F+ V G L E A+ F+Q++ A+ + Sbjct: 65 LDHKNIIQVYEMLESADGKICLVMELAEGGDVFDCVLNGGPLPESRAKALFRQMVEAIRY 124 Query: 983 CHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVIN 1162 CH GV HRDLK EN LL + NLK++DFG + + + L T CG+ AY APEV+ Sbjct: 125 CHGCGVAHRDLKCENALL-QGFNLKLTDFGFAKVLPKSHRE-LSQTFCGSTAYAAPEVLQ 182 Query: 1163 RKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNM-YKKIGKAEFKCPSWFSSDXXXXX 1339 +D K D+WS GV+L+V++ LPF D ++ M +++ F S+D Sbjct: 183 GIPHDSKKGDVWSMGVVLYVMLCASLPFDDTDIPKMLWQQQKGVSFPTHLSISADCQDLL 242 Query: 1340 XXXXDPNPSTRISIEKIMEHPW 1405 +P+ R SIE++ HPW Sbjct: 243 KRLLEPDMILRPSIEEVSWHPW 264
>O61267:LOK_DROME Ovarian-specific serine/threonine-protein kinase Lok - Drosophila| melanogaster (Fruit fly) Length = 476 Score = 163 bits (412), Expect = 3e-39 Identities = 102/282 (36%), Positives = 153/282 (54%), Gaps = 17/282 (6%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLT-------DQIKREISVM 802 Y + + LG G + V + T Q A+K+ K+ +L G D++ E +M Sbjct: 174 YYVNRKLGSGAYGLVRLVYDTRTCQQFAMKIV-KKNMLSGARPSTNFSDPDRVLNEAKIM 232 Query: 803 KLVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQRGRL-KEDAARKYFQQLICAVD 979 K + HP +V+M++++ +Y VLE ++GG+L N++ +L ED ++ YF Q+ AV Sbjct: 233 KNLSHPCVVRMHDIVDKPDSVYMVLEFMRGGDLLNRIISNKLLSEDISKLYFYQMCHAVK 292 Query: 980 FCHSRGVYHRDLKPENLLL---DENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAP 1150 + H RG+ HRDLKP+N+LL DE + LKVSDFGLS + D ++ T CGTP YVAP Sbjct: 293 YLHDRGITHRDLKPDNVLLETNDEETLLKVSDFGLSKFVQ---KDSVMRTLCGTPLYVAP 349 Query: 1151 EVINRKGYDG--AKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKC--PSW-- 1312 EV+ G + K DIWS GV+LF ++G LPF D+ ++I K F PSW Sbjct: 350 EVLITGGREAYTKKVDIWSLGVVLFTCLSGTLPFSDEYGTPAAQQIKKGRFAYGHPSWKS 409 Query: 1313 FSSDXXXXXXXXXDPNPSTRISIEKIMEHPWFRKGLDAKLLR 1438 S +P R SI+ +++ W R DA +L+ Sbjct: 410 VSQRAKLLINQMLIVDPERRPSIDDVLQSSWLR---DAPMLQ 448
>Q4KTY1:KPSH1_PINFU Serine/threonine-protein kinase H1 homolog - Pinctada fucata (Pearl| oyster) Length = 415 Score = 163 bits (412), Expect = 3e-39 Identities = 92/263 (34%), Positives = 149/263 (56%), Gaps = 8/263 (3%) Frame = +2 Query: 641 KYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHP 820 KY++ ++G+G F+KV + T Q AIK+ D+ ++G + + E++V++ VKH Sbjct: 79 KYDIKALIGRGNFSKVVRVEHRVTKQPYAIKMIDR---VQG--KEVFESEVAVLRRVKHS 133 Query: 821 NIVQMYEVMATKTKIYFVLEHVKGGELFNK-VQRGRLKEDAARKYFQQLICAVDFCHSRG 997 I+Q+ EV TK K+Y V+E GGELF++ + +G E A + ++ V + H G Sbjct: 134 YIIQLIEVFETKDKVYMVMELATGGELFDRIIAKGSFTERDATRVLNMVLDGVKYLHGLG 193 Query: 998 VYHRDLKPENLLL---DENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRK 1168 + HRDLKPENLL +S + ++DFGLS S + + + T+CGTP Y+APE+I RK Sbjct: 194 ITHRDLKPENLLYYHPGHDSKIMITDFGLS--STRKGPENFMRTTCGTPEYIAPEIIARK 251 Query: 1169 GYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXX 1348 Y + D+W+ GVI ++L++G +PF D+N +Y+ I KA++ D Sbjct: 252 PY-MCQVDMWAVGVITYILLSGTMPFDDENKTRLYRLILKAKYSYAGEHWKDVSAQAKDF 310 Query: 1349 XDP----NPSTRISIEKIMEHPW 1405 D +P R+S ++H W Sbjct: 311 IDKLLVVSPGDRLSAADALKHQW 333
>P17612:KAPCA_HUMAN cAMP-dependent protein kinase, alpha-catalytic subunit - Homo sapiens| (Human) Length = 351 Score = 163 bits (412), Expect = 3e-39 Identities = 91/264 (34%), Positives = 147/264 (55%), Gaps = 6/264 (2%) Frame = +2 Query: 635 MHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVK 814 + ++E K LG G+F +V ++ ET A+K+ DK+KV+K + E +++ V Sbjct: 41 LDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVN 100 Query: 815 HPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQR-GRLKEDAARKYFQQLICAVDFCHS 991 P +V++ + +Y V+E+V GGE+F+ ++R GR E AR Y Q++ ++ HS Sbjct: 101 FPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHS 160 Query: 992 RGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKG 1171 + +RDLKPENLL+D+ ++V+DFG + +R+ G T CGTP Y+APE+I KG Sbjct: 161 LDLIYRDLKPENLLIDQQGYIQVTDFGFA-----KRVKGRTWTLCGTPEYLAPEIILSKG 215 Query: 1172 YDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXXX 1351 Y+ A D W+ GV+++ + AGY PF + +Y+KI + + PS FSSD Sbjct: 216 YNKA-VDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLL 274 Query: 1352 DPNPSTRI-----SIEKIMEHPWF 1408 + + R + I H WF Sbjct: 275 QVDLTKRFGNLKNGVNDIKNHKWF 298
>Q8MJ44:KAPCA_CANFA cAMP-dependent protein kinase, alpha-catalytic subunit - Canis| familiaris (Dog) Length = 350 Score = 163 bits (412), Expect = 3e-39 Identities = 91/264 (34%), Positives = 147/264 (55%), Gaps = 6/264 (2%) Frame = +2 Query: 635 MHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVK 814 + ++E K LG G+F +V ++ ET A+K+ DK+KV+K + E +++ V Sbjct: 40 LDQFERIKTLGTGSFGRVMLVKHKETGNHFAMKILDKQKVVKLKQIEHTLNEKRILQAVN 99 Query: 815 HPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQR-GRLKEDAARKYFQQLICAVDFCHS 991 P +V++ + +Y V+E+V GGE+F+ ++R GR E AR Y Q++ ++ HS Sbjct: 100 FPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHS 159 Query: 992 RGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKG 1171 + +RDLKPENLL+D+ ++V+DFG + +R+ G T CGTP Y+APE+I KG Sbjct: 160 LDLIYRDLKPENLLIDQQGYIQVTDFGFA-----KRVKGRTWTLCGTPEYLAPEIILSKG 214 Query: 1172 YDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXXX 1351 Y+ A D W+ GV+++ + AGY PF + +Y+KI + + PS FSSD Sbjct: 215 YNKA-VDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLL 273 Query: 1352 DPNPSTRI-----SIEKIMEHPWF 1408 + + R + I H WF Sbjct: 274 QVDLTKRFGNLKNGVNDIKNHKWF 297
>P24256:KAPB2_BOVIN cAMP-dependent protein kinase, beta-2-catalytic subunit - Bos taurus| (Bovine) Length = 397 Score = 163 bits (412), Expect = 3e-39 Identities = 92/267 (34%), Positives = 146/267 (54%), Gaps = 6/267 (2%) Frame = +2 Query: 626 NILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMK 805 N + +E K LG G+F +V ++ T Q A+K+ DK+KV+K + E +++ Sbjct: 84 NAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQ 143 Query: 806 LVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQR-GRLKEDAARKYFQQLICAVDF 982 V P +V++ + +Y V+E+V GGE+F+ ++R GR E AR Y Q++ ++ Sbjct: 144 AVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEY 203 Query: 983 CHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVIN 1162 HS + +RDLKPENLL+D ++V+DFG + +R+ G T CGTP Y+APE+I Sbjct: 204 LHSLDLIYRDLKPENLLIDHQGYIQVTDFGFA-----KRVKGRTWTLCGTPEYLAPEIIL 258 Query: 1163 RKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXX 1342 KGY+ A D W+ GV+++ + AGY PF + +Y+KI + + PS FSSD Sbjct: 259 SKGYNKA-VDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLR 317 Query: 1343 XXXDPNPSTRI-----SIEKIMEHPWF 1408 + + R + I H WF Sbjct: 318 NLLQVDLTKRFGNLKNGVSDIKTHKWF 344
>P05131:KAPB1_BOVIN cAMP-dependent protein kinase, beta-1-catalytic subunit - Bos taurus| (Bovine) Length = 351 Score = 163 bits (412), Expect = 3e-39 Identities = 92/267 (34%), Positives = 146/267 (54%), Gaps = 6/267 (2%) Frame = +2 Query: 626 NILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMK 805 N + +E K LG G+F +V ++ T Q A+K+ DK+KV+K + E +++ Sbjct: 38 NAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQ 97 Query: 806 LVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQR-GRLKEDAARKYFQQLICAVDF 982 V P +V++ + +Y V+E+V GGE+F+ ++R GR E AR Y Q++ ++ Sbjct: 98 AVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEY 157 Query: 983 CHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVIN 1162 HS + +RDLKPENLL+D ++V+DFG + +R+ G T CGTP Y+APE+I Sbjct: 158 LHSLDLIYRDLKPENLLIDHQGYIQVTDFGFA-----KRVKGRTWTLCGTPEYLAPEIIL 212 Query: 1163 RKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXX 1342 KGY+ A D W+ GV+++ + AGY PF + +Y+KI + + PS FSSD Sbjct: 213 SKGYNKA-VDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLR 271 Query: 1343 XXXDPNPSTRI-----SIEKIMEHPWF 1408 + + R + I H WF Sbjct: 272 NLLQVDLTKRFGNLKNGVSDIKTHKWF 298
>Q9WUT3:KS6A2_MOUSE Ribosomal protein S6 kinase alpha-2 - Mus musculus (Mouse)| Length = 733 Score = 162 bits (411), Expect = 4e-39 Identities = 94/265 (35%), Positives = 152/265 (57%), Gaps = 9/265 (3%) Frame = +2 Query: 641 KYEMGKMLGQGTFAKVYHARNI---ETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLV 811 ++E+ K+LGQG++ KV+ R + + Q A+KV K+ LK + K E ++ V Sbjct: 58 QFELLKVLGQGSYGKVFLVRKVTGSDAGQLYAMKVL-KKATLKVRDRVRSKMERDILAEV 116 Query: 812 KHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQRGRL-KEDAARKYFQQLICAVDFCH 988 HP IV+++ T+ K+Y +L+ ++GG+LF ++ + + E+ + Y +L A+D H Sbjct: 117 NHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLH 176 Query: 989 SRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRK 1168 G+ +RDLKPEN+LLDE ++K++DFGLS E D ++ CGT Y+APEV+NR+ Sbjct: 177 GLGIIYRDLKPENILLDEEGHIKITDFGLS--KEATDHDKRAYSFCGTIEYMAPEVVNRR 234 Query: 1169 GYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXX 1348 G+ AD WS GV++F ++ G LPFQ K+ I KA+ P + S++ Sbjct: 235 GHT-QSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLGMPQFLSAEAQSLLRAL 293 Query: 1349 XDPNPSTRI-----SIEKIMEHPWF 1408 NP R+ +E+I HP+F Sbjct: 294 FKRNPCNRLGAGVDGVEEIKRHPFF 318 Score = 134 bits (338), Expect = 1e-30 Identities = 82/266 (30%), Positives = 141/266 (53%), Gaps = 12/266 (4%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 YE+ + +G G+++ + T A+K+ DK K D + +++ +HPN Sbjct: 415 YEIKEDIGVGSYSVCKRCVHKATDAEYAVKIIDKSK------RDPSEEIEILLRYGQHPN 468 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNKVQRGR-LKEDAARKYFQQLICAVDFCHSRGV 1000 I+ + +V +Y V+E ++GGEL +++ R R E A + +D+ HS+GV Sbjct: 469 IITLKDVYDDGKYVYLVMELMRGGELLDRILRQRCFSEREASDVLYTIARTMDYLHSQGV 528 Query: 1001 YHRDLKPENLL-LDENSN---LKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRK 1168 HRDLKP N+L +DE+ N +++ DFG + + R +GLL T C T +VAPEV+ R+ Sbjct: 529 VHRDLKPSNILYMDESGNPESIRICDFGFA--KQLRAENGLLMTPCYTANFVAPEVLKRQ 586 Query: 1169 GYDGAKADIWSCGVILFVLMAGYLPF---QDKNLMNMYKKIGKAEFKCP--SW--FSSDX 1327 GYD A D+WS G++L+ ++AG+ PF D + +IG ++ +W S Sbjct: 587 GYDAA-CDVWSLGILLYTMLAGFTPFANGPDDTPEEILARIGSGKYALSGGNWDSISDAA 645 Query: 1328 XXXXXXXXDPNPSTRISIEKIMEHPW 1405 +P R++ ++++HPW Sbjct: 646 KDVVSKMLHVDPQQRLTAVQVLKHPW 671
>P68182:KAPCB_RAT cAMP-dependent protein kinase, beta-catalytic subunit - Rattus| norvegicus (Rat) Length = 351 Score = 162 bits (411), Expect = 4e-39 Identities = 92/267 (34%), Positives = 147/267 (55%), Gaps = 6/267 (2%) Frame = +2 Query: 626 NILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMK 805 N + +E K LG G+F +V ++ T Q A+K+ DK+KV+K + E +++ Sbjct: 38 NAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQ 97 Query: 806 LVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQR-GRLKEDAARKYFQQLICAVDF 982 V+ P +V++ + +Y V+E+V GGE+F+ ++R GR E AR Y Q++ ++ Sbjct: 98 AVEFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEY 157 Query: 983 CHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVIN 1162 HS + +RDLKPENLL+D ++V+DFG + +R+ G T CGTP Y+APE+I Sbjct: 158 LHSLDLIYRDLKPENLLIDHQGYIQVTDFGFA-----KRVKGRTWTLCGTPEYLAPEIIL 212 Query: 1163 RKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXX 1342 KGY+ A D W+ GV+++ + AGY PF + +Y+KI + + PS FSSD Sbjct: 213 SKGYNKA-VDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLR 271 Query: 1343 XXXDPNPSTRI-----SIEKIMEHPWF 1408 + + R + I H WF Sbjct: 272 NLLQVDLTKRFGNLKNGVSDIKTHKWF 298
>P68181:KAPCB_MOUSE cAMP-dependent protein kinase, beta-catalytic subunit - Mus musculus| (Mouse) Length = 351 Score = 162 bits (411), Expect = 4e-39 Identities = 92/267 (34%), Positives = 147/267 (55%), Gaps = 6/267 (2%) Frame = +2 Query: 626 NILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMK 805 N + +E K LG G+F +V ++ T Q A+K+ DK+KV+K + E +++ Sbjct: 38 NAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQ 97 Query: 806 LVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQR-GRLKEDAARKYFQQLICAVDF 982 V+ P +V++ + +Y V+E+V GGE+F+ ++R GR E AR Y Q++ ++ Sbjct: 98 AVEFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEY 157 Query: 983 CHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVIN 1162 HS + +RDLKPENLL+D ++V+DFG + +R+ G T CGTP Y+APE+I Sbjct: 158 LHSLDLIYRDLKPENLLIDHQGYIQVTDFGFA-----KRVKGRTWTLCGTPEYLAPEIIL 212 Query: 1163 RKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXX 1342 KGY+ A D W+ GV+++ + AGY PF + +Y+KI + + PS FSSD Sbjct: 213 SKGYNKA-VDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLR 271 Query: 1343 XXXDPNPSTRI-----SIEKIMEHPWF 1408 + + R + I H WF Sbjct: 272 NLLQVDLTKRFGNLKNGVSDIKTHKWF 298
>P68180:KAPCB_CRIGR cAMP-dependent protein kinase, beta-catalytic subunit - Cricetulus| griseus (Chinese hamster) Length = 351 Score = 162 bits (411), Expect = 4e-39 Identities = 92/267 (34%), Positives = 147/267 (55%), Gaps = 6/267 (2%) Frame = +2 Query: 626 NILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMK 805 N + +E K LG G+F +V ++ T Q A+K+ DK+KV+K + E +++ Sbjct: 38 NAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQ 97 Query: 806 LVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQR-GRLKEDAARKYFQQLICAVDF 982 V+ P +V++ + +Y V+E+V GGE+F+ ++R GR E AR Y Q++ ++ Sbjct: 98 AVEFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEY 157 Query: 983 CHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVIN 1162 HS + +RDLKPENLL+D ++V+DFG + +R+ G T CGTP Y+APE+I Sbjct: 158 LHSLDLIYRDLKPENLLIDHQGYIQVTDFGFA-----KRVKGRTWTLCGTPEYLAPEIIL 212 Query: 1163 RKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXX 1342 KGY+ A D W+ GV+++ + AGY PF + +Y+KI + + PS FSSD Sbjct: 213 SKGYNKA-VDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLR 271 Query: 1343 XXXDPNPSTRI-----SIEKIMEHPWF 1408 + + R + I H WF Sbjct: 272 NLLQVDLTKRFGNLKNGVSDIKTHKWF 298
>Q96GD4:AURKB_HUMAN Serine/threonine-protein kinase 12 - Homo sapiens (Human)| Length = 344 Score = 162 bits (411), Expect = 4e-39 Identities = 87/257 (33%), Positives = 141/257 (54%), Gaps = 1/257 (0%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 +E+G+ LG+G F VY AR ++ VA+KV K ++ K G+ Q++REI + + HPN Sbjct: 77 FEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPN 136 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNKVQRG-RLKEDAARKYFQQLICAVDFCHSRGV 1000 I+++Y + +IY +LE+ GEL+ ++Q+ E ++L A+ +CH + V Sbjct: 137 ILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHGKKV 196 Query: 1001 YHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKGYDG 1180 HRD+KPENLLL LK++DFG S + R T CGT Y+ PE+I + ++ Sbjct: 197 IHRDIKPENLLLGLKGELKIADFGWSVHAPSLR----RKTMCGTLDYLPPEMIEGRMHN- 251 Query: 1181 AKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXXXDPN 1360 K D+W GV+ + L+ G PF+ + Y++I K + K P+ + N Sbjct: 252 EKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPTGAQDLISKLLRHN 311 Query: 1361 PSTRISIEKIMEHPWFR 1411 PS R+ + ++ HPW R Sbjct: 312 PSERLPLAQVSAHPWVR 328
>Q9URY1:PPK16_SCHPO Serine/threonine-protein kinase ppk16 - Schizosaccharomyces pombe| (Fission yeast) Length = 672 Score = 162 bits (410), Expect = 5e-39 Identities = 90/258 (34%), Positives = 146/258 (56%), Gaps = 1/258 (0%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 Y + ++G+G+F KVY A ++ T+ V +K + +++ + + REI + + HPN Sbjct: 31 YRIESVVGEGSFGKVYLAAHLLTNTKVVLKSSCRKQAII------LAREIHHHRRLLHPN 84 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNKVQRG-RLKEDAARKYFQQLICAVDFCHSRGV 1000 I ++YEV+ T+ +IY +E+ GEL++ V R RL E + QL CA+ + H +G Sbjct: 85 ITRLYEVVCTEDRIYLAMEYCPNGELYDWVAREKRLDEKTTCRIMWQLCCAIQYLHRQGC 144 Query: 1001 YHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKGYDG 1180 HRDLK EN+ LD+ N+K+ DFG S S+C R ++T CGT AY APE++ Y G Sbjct: 145 VHRDLKLENIFLDKAYNVKLGDFGFSRDSDCSRRT-FMNTRCGTVAYCAPELVQGHKYIG 203 Query: 1181 AKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXXXDPN 1360 DIWS G+I++ L+ G LPF + ++ +KI + P S + + Sbjct: 204 ECVDIWSLGIIMYALLIGRLPFDEDDVSLTEQKIINECPQYPETLSKNSSSLLKSLLCKD 263 Query: 1361 PSTRISIEKIMEHPWFRK 1414 R SI++I+ HP+F++ Sbjct: 264 YRLRPSIDQIISHPYFKE 281
>Q9D411:TSSK4_MOUSE Testis-specific serine/threonine-protein kinase 4 - Mus musculus| (Mouse) Length = 328 Score = 162 bits (409), Expect = 7e-39 Identities = 92/272 (33%), Positives = 147/272 (54%), Gaps = 15/272 (5%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 YE+GK++G G++ VY A + VA+K+ K+K + L + REI VMK+++H Sbjct: 25 YEVGKIIGHGSYGTVYEAYYTKQKVMVAVKIISKKKASEDYLNKFLPREIQVMKVLRHKY 84 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNKVQR-GRLKEDAARKYFQQLICAVDFCHSRGV 1000 ++ Y+ + T +++Y +LE +GG++ +QR G E A K+F Q+ + + HS+G+ Sbjct: 85 LINFYQAIETTSRVYIILELAQGGDVLEWIQRYGACAETLAGKWFSQMALGIAYLHSKGI 144 Query: 1001 YHRDLKPENLLLDENSNLKVSDFGLSTI----------SECRRLDGLLH---TSCGTPAY 1141 HRDLK ENLLLD+ N+K+SDFG + + R+++ L H T CG+ AY Sbjct: 145 VHRDLKLENLLLDKRENVKISDFGFAKMVPSSQPVHSSPSYRQMNSLSHLSQTYCGSFAY 204 Query: 1142 VAPEVINRKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSS 1321 PE++ Y+ +D WS GVIL+ L+ LPF D NL + ++ K E P+ + Sbjct: 205 ACPEILLGLPYNPFLSDTWSMGVILYTLVVARLPFDDTNLKKLLRETQK-EVTFPANLTI 263 Query: 1322 DXXXXXXXXXDPNPST-RISIEKIMEHPWFRK 1414 ST R +I ++ PW K Sbjct: 264 SQECKNLILQLLRQSTKRATILDVLRDPWMLK 295
>Q15831:STK11_HUMAN Serine/threonine-protein kinase 11 - Homo sapiens (Human)| Length = 433 Score = 162 bits (409), Expect = 7e-39 Identities = 91/268 (33%), Positives = 146/268 (54%), Gaps = 7/268 (2%) Frame = +2 Query: 632 LMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKV--LKGGLTDQIKREISVMK 805 L+ KY MG +LG+G++ KV + ET A+K+ K+K+ + G + +K+EI +++ Sbjct: 45 LIGKYLMGDLLGEGSYGKVKEVLDSETLCRRAVKILKKKKLRRIPNGEAN-VKKEIQLLR 103 Query: 806 LVKHPNIVQMYEVMAT--KTKIYFVLEHVKGG--ELFNKVQRGRLKEDAARKYFQQLICA 973 ++H N++Q+ +V+ K K+Y V+E+ G E+ + V R A YF QLI Sbjct: 104 RLRHKNVIQLVDVLYNEEKQKMYMVMEYCVCGMQEMLDSVPEKRFPVCQAHGYFCQLIDG 163 Query: 974 VDFCHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPE 1153 +++ HS+G+ H+D+KP NLLL LK+SD G++ D TS G+PA+ PE Sbjct: 164 LEYLHSQGIVHKDIKPGNLLLTTGGTLKISDLGVAEALHPFAADDTCRTSQGSPAFQPPE 223 Query: 1154 VIN-RKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXX 1330 + N + G K DIWS GV L+ + G PF+ N+ +++ IGK + P Sbjct: 224 IANGLDTFSGFKVDIWSAGVTLYNITTGLYPFEGDNIYKLFENIGKGSYAIPGDCGPPLS 283 Query: 1331 XXXXXXXDPNPSTRISIEKIMEHPWFRK 1414 + P+ R SI +I +H WFRK Sbjct: 284 DLLKGMLEYEPAKRFSIRQIRQHSWFRK 311
>Q21734:KS6A1_CAEEL Putative ribosomal protein S6 kinase alpha-1 - Caenorhabditis elegans| Length = 784 Score = 162 bits (409), Expect = 7e-39 Identities = 96/274 (35%), Positives = 158/274 (57%), Gaps = 9/274 (3%) Frame = +2 Query: 641 KYEMGKMLGQGTFAKVYHARNIETSQS---VAIKVTDKEKVLKGGLTDQIKREISVMKLV 811 ++E+ K+LGQG+F KV+ R + S A+KV K+ LK + K E +++ + Sbjct: 103 QFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVL-KKATLKVRDRQRTKLERNILAHI 161 Query: 812 KHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQRGRL-KEDAARKYFQQLICAVDFCH 988 HP IV+++ T+ K+Y +L+ ++GG+LF ++ + + ED + Y +L A++ H Sbjct: 162 SHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEDDVKFYLAELTLALEHLH 221 Query: 989 SRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRK 1168 S G+ +RDLKPEN+LLD + ++KV+DFGLS E + ++ CGT Y+APEVINR+ Sbjct: 222 SLGIVYRDLKPENILLDADGHIKVTDFGLS--KEAIDSEKKTYSFCGTVEYMAPEVINRR 279 Query: 1169 GYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXX 1348 G+ A AD WS GV++F ++ G+LPFQ ++ + +I KA+ P + + + Sbjct: 280 GHSMA-ADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILKAKLSMPHFLTQEAQSLLRAL 338 Query: 1349 XDPNPSTRI-----SIEKIMEHPWFRKGLDAKLL 1435 N R+ +E+I H +F K KLL Sbjct: 339 FKRNSQNRLGAGPDGVEEIKRHAFFAKIDFVKLL 372 Score = 113 bits (283), Expect = 3e-24 Identities = 82/279 (29%), Positives = 135/279 (48%), Gaps = 17/279 (6%) Frame = +2 Query: 620 KGNILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISV 799 K N YE+ + +G G + V+ + T + A+K+ K + D + + Sbjct: 446 KTNPFTDDYEILEKIGNGAHSVVHKCQMKATRRKYAVKIVKK------AVFDATEEVDIL 499 Query: 800 MKLVKHPNIVQMYEVMATKTKIYFVLEHVKGGELF----NKVQRGRLKEDAARKYFQQLI 967 ++ H +V++++V +T IY + E +GGEL NK G KE AA L+ Sbjct: 500 LRHSHHQFVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAA--IMANLL 557 Query: 968 CAVDFCHSRGVYHRDLKPENLLL----DENSNLKVSDFGLSTISECRRLDGLLHTSCGTP 1135 AV + HS+ V HRDL N+L + S+L++ DFG + + R +G+L T C T Sbjct: 558 NAVQYLHSQQVAHRDLTAANILFALKDGDPSSLRIVDFGFA--KQSRAENGMLMTPCYTA 615 Query: 1136 AYVAPEVINRKGYDGAKADIWSCGVILFVLMAGYLPF-------QDKNLMNMYKKIGKAE 1294 +VAPEV+ ++GYD D+WS GV+L ++ G PF D+ L + GK Sbjct: 616 QFVAPEVLRKQGYD-RSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGD--GKIS 672 Query: 1295 FKCPSW--FSSDXXXXXXXXXDPNPSTRISIEKIMEHPW 1405 P W S + D +P+ R++ ++ ++H W Sbjct: 673 MTHPVWDTISDEAKDLVRKMLDVDPNRRVTAKQALQHKW 711
>Q9P7I2:KCC1_SCHPO Calcium/calmodulin-dependent protein kinase type I -| Schizosaccharomyces pombe (Fission yeast) Length = 335 Score = 162 bits (409), Expect = 7e-39 Identities = 101/279 (36%), Positives = 155/279 (55%), Gaps = 10/279 (3%) Frame = +2 Query: 599 PAIMGEQKGNILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQ 778 P +QK +L KY +G++LG GT+A V A +IET++ A K+ +K+ + K D Sbjct: 17 PKATVDQK-QLLPCKYRVGRVLGGGTYATVREAVHIETNKMYAAKIMNKKMMEK--KQDF 73 Query: 779 IKREISVMKLV--KHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKV-QRGRLKEDAARK 949 +K EI+++K V +HPNI+ + + T +Y + E GGELF+++ +G E A Sbjct: 74 VKNEIAILKRVSYEHPNILHLVDFFETVNNLYLITELATGGELFDRICAKGSFYEADAAA 133 Query: 950 YFQQLICAVDFCHSRGVYHRDLKPENLLL---DENSNLKVSDFGLSTISECRRLDGLLHT 1120 + AV + H G+ HRDLKPENLL D NS+L ++DFGLS E + +L T Sbjct: 134 LMRTTTSAVKYLHDNGIVHRDLKPENLLYRSKDPNSDLLIADFGLSHFYEDSQY-YMLMT 192 Query: 1121 SCGTPAYVAPEVINRKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEF- 1297 +CGTP Y+APEV R GY G D+W+ GVI + L++GY PF + + + + I E+ Sbjct: 193 ACGTPEYMAPEVFRRTGY-GKPVDMWAIGVITYFLLSGYTPFARPSQVEVIEAILANEYT 251 Query: 1298 ---KCPSWFSSDXXXXXXXXXDPNPSTRISIEKIMEHPW 1405 C S S + +PS R++ ++HP+ Sbjct: 252 FNDPCWSGISETAKDFIKKCLENDPSKRLTAADALKHPF 290
>P05383:KAPCB_PIG cAMP-dependent protein kinase, beta-catalytic subunit - Sus scrofa| (Pig) Length = 351 Score = 162 bits (409), Expect = 7e-39 Identities = 92/267 (34%), Positives = 146/267 (54%), Gaps = 6/267 (2%) Frame = +2 Query: 626 NILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMK 805 N + +E K LG G+F +V ++ T Q A+K+ DK+KV+K + E +++ Sbjct: 38 NAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQ 97 Query: 806 LVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQR-GRLKEDAARKYFQQLICAVDF 982 V P +V++ + +Y V+E+V GGE+F+ ++R GR E AR Y Q++ ++ Sbjct: 98 AVNFPFLVRLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEY 157 Query: 983 CHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVIN 1162 HS + +RDLKPENLL+D ++V+DFG + +R+ G T CGTP Y+APE+I Sbjct: 158 LHSLDLIYRDLKPENLLIDHQGYIQVTDFGFA-----KRVKGRTWTLCGTPEYLAPEIIL 212 Query: 1163 RKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXX 1342 KGY+ A D W+ GV+++ + AGY PF + +Y+KI + + PS FSSD Sbjct: 213 SKGYNKA-VDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLR 271 Query: 1343 XXXDPNPSTRI-----SIEKIMEHPWF 1408 + + R + I H WF Sbjct: 272 NLLQVDLTKRFGNLKNGVSDIKTHKWF 298
>Q96PF2:TSSK2_HUMAN Testis-specific serine/threonine-protein kinase 2 - Homo sapiens| (Human) Length = 358 Score = 161 bits (407), Expect = 1e-38 Identities = 93/264 (35%), Positives = 147/264 (55%), Gaps = 8/264 (3%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 Y +G LG+G++AKV A + +VA+K+ D++K + + RE+ ++ V H + Sbjct: 12 YIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLPREMDILATVNHGS 71 Query: 824 IVQMYEVMATKT-KIYFVLEHVKGGELFNKVQ-RGRLKEDAARKYFQQLICAVDFCHSRG 997 I++ YE+ T +IY ++E G+L ++ +G L ED ARK F+QL AV +CH Sbjct: 72 IIKTYEIFETSDGRIYIIMELGVQGDLLEFIKCQGALHEDVARKMFRQLSSAVKYCHDLD 131 Query: 998 VYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDG----LLHTSCGTPAYVAPEVINR 1165 + HRDLK ENLLLD++ N+K+SDFG S C R L T CG+ AY APEV+ Sbjct: 132 IVHRDLKCENLLLDKDFNIKLSDFGFS--KRCLRDSNGRIILSKTFCGSAAYAAPEVLQS 189 Query: 1166 KGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYK--KIGKAEFKCPSWFSSDXXXXX 1339 Y DIWS GVIL++++ G +P+ D ++ M + K + +F + + Sbjct: 190 IPYQPKVYDIWSLGVILYIMVCGSMPYDDSDIRKMLRIQKEHRVDFPRSKNLTCECKDLI 249 Query: 1340 XXXXDPNPSTRISIEKIMEHPWFR 1411 P+ S R+ I++I+ H W + Sbjct: 250 YRMLQPDVSQRLHIDEILSHSWLQ 273
>O59697:PPK25_SCHPO Serine/threonine-protein kinase ppk25 - Schizosaccharomyces pombe| (Fission yeast) Length = 423 Score = 161 bits (407), Expect = 1e-38 Identities = 93/270 (34%), Positives = 150/270 (55%), Gaps = 2/270 (0%) Frame = +2 Query: 611 GEQKGNILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKRE 790 G Q GN ++ K +G G+ KV NI T + A+K+ T +++RE Sbjct: 47 GRQVGNWIIKK-----TIGAGSMGKVKLVVNILTGEKAALKMIPFTPN-NTSQTVRVQRE 100 Query: 791 ISVMKLVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKV-QRGRLKEDAARKYFQQLI 967 + +L++HPNI ++ + + T Y + E+V GG+L + RG+L ED AR + QLI Sbjct: 101 ALLGRLLRHPNICRVIDCIRTPACTYILFEYVPGGQLLEYILARGKLDEDLARSFAMQLI 160 Query: 968 CAVDFCHSRGVYHRDLKPENLLLDENSN-LKVSDFGLSTISECRRLDGLLHTSCGTPAYV 1144 A+ + H + HRDLK EN+LL ++S +K+ DFGLS D LL T CG+ + Sbjct: 161 NALVYLHKNFIVHRDLKIENVLLTQDSRQVKLIDFGLSNFYS---KDDLLRTYCGSLYFA 217 Query: 1145 APEVINRKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSD 1324 APE+++ K Y G + D+WS GV+++V++ G +PF D ++ ++ KI + + PS+ S D Sbjct: 218 APELLDAKPYIGPEVDVWSLGVVIYVMVCGRVPFDDVSVPMLHSKIKSGKLEFPSYISED 277 Query: 1325 XXXXXXXXXDPNPSTRISIEKIMEHPWFRK 1414 + NP R S+E+ + PW +K Sbjct: 278 CCSLIAAMLNVNPRKRCSLEQAAKFPWLKK 307
>P25321:KAPCA_CRIGR cAMP-dependent protein kinase, alpha-catalytic subunit - Cricetulus| griseus (Chinese hamster) Length = 351 Score = 161 bits (407), Expect = 1e-38 Identities = 90/257 (35%), Positives = 143/257 (55%), Gaps = 6/257 (2%) Frame = +2 Query: 656 KMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPNIVQM 835 K LG G+F +V ++ ET A+K+ DK+KV+K + E +++ V P +V++ Sbjct: 48 KTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKL 107 Query: 836 YEVMATKTKIYFVLEHVKGGELFNKVQR-GRLKEDAARKYFQQLICAVDFCHSRGVYHRD 1012 + +Y V+E+V GGE+F+ ++R GR E AR Y Q++ ++ HS + +RD Sbjct: 108 EFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRD 167 Query: 1013 LKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKGYDGAKAD 1192 LKPENLL+D+ ++V+DFG + +R+ G T CGTP Y+APE+I KGY+ A D Sbjct: 168 LKPENLLIDQQGYIQVTDFGFA-----KRVKGRTWTLCGTPEYLAPEIILSKGYNKA-VD 221 Query: 1193 IWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXXXDPNPSTR 1372 W+ GV+++ + AGY PF + +Y+KI + + PS FSSD + + R Sbjct: 222 WWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKR 281 Query: 1373 I-----SIEKIMEHPWF 1408 + I H WF Sbjct: 282 FGNLKNGVNDIKNHKWF 298
>Q6BVA0:IPL1_DEBHA Spindle assembly checkpoint kinase - Debaryomyces hansenii (Yeast)| (Torulaspora hansenii) Length = 412 Score = 161 bits (407), Expect = 1e-38 Identities = 89/266 (33%), Positives = 147/266 (55%), Gaps = 6/266 (2%) Frame = +2 Query: 626 NILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMK 805 ++ + +E+GK+LG+G KVY ++ + A+KV K+ ++ L +REI + Sbjct: 142 HMTLDDFEIGKVLGKGKLGKVYCVKHKTSGYIAALKVMAKKDLIDLKLEKNFRREIEIQS 201 Query: 806 LVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFN--KVQRGRLKEDAARKYFQQLICAVD 979 + HP I ++Y +Y +LE+ GEL++ KVQR R + A Y Q+ A+D Sbjct: 202 NLIHPKISRLYGFFYDHKNVYLILEYSIHGELYHHLKVQR-RFNDATASHYIYQVALALD 260 Query: 980 FCHSRGVYHRDLKPENLLLDENSNLKVSDFGLST----ISECRRLDGLLHTSCGTPAYVA 1147 + H++ + HRD+KPEN+LL ++ +K+SDFG S S +RL T CGT Y+ Sbjct: 261 YLHTKHIIHRDIKPENILLSTDNCIKLSDFGWSVKSLPSSSTKRL-----TICGTLDYLP 315 Query: 1148 PEVINRKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDX 1327 PE+I +D DIWS G++ + + G PF++ + + YK+I K + K PS+ SS+ Sbjct: 316 PEMIESNEHDYT-VDIWSLGILCYEFLVGKPPFEEIDKNSTYKRIAKVDLKIPSFLSSEA 374 Query: 1328 XXXXXXXXDPNPSTRISIEKIMEHPW 1405 +P RI++ ++M HPW Sbjct: 375 TDLILRLLQKSPKKRITLAEVMNHPW 400
>P54644:KRAC_DICDI RAC-family serine/threonine-protein kinase homolog - Dictyostelium| discoideum (Slime mold) Length = 444 Score = 160 bits (406), Expect = 2e-38 Identities = 88/264 (33%), Positives = 151/264 (57%), Gaps = 8/264 (3%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 +E+ ++G+G+F KV R +T + A+KV K+ +++ + E ++++ + HP Sbjct: 120 FELLNLVGKGSFGKVIQVRKKDTGEVYAMKVLSKKHIVEHNEVEHTLSERNILQKINHPF 179 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNKVQRG-RLKEDAARKYFQQLICAVDFCHSRGV 1000 +V + T+ K+YF+L++V GGELF +Q+ + ED R Y +++ A++ H GV Sbjct: 180 LVNLNYSFQTEDKLYFILDYVNGGELFYHLQKDKKFTEDRVRYYGAEIVLALEHLHLSGV 239 Query: 1001 YHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLL------HTSCGTPAYVAPEVIN 1162 +RDLKPENLLL ++ ++DFGL C+ +GLL T CGTP Y+APEV+ Sbjct: 240 IYRDLKPENLLLTNEGHICMTDFGL-----CK--EGLLTPTDKTGTFCGTPEYLAPEVLQ 292 Query: 1163 RKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXX 1342 GY G + D WS G +L+ ++ G PF ++++ MY+KI + P + S D Sbjct: 293 GNGY-GKQVDWWSFGSLLYEMLTGLPPFYNQDVQEMYRKIMMEKLSFPHFISPDARSLLE 351 Query: 1343 XXXDPNPSTRISIEKIME-HPWFR 1411 + +P R++ +++ HP+FR Sbjct: 352 QLLERDPEKRLADPNLIKRHPFFR 375
>P34099:KAPC_DICDI cAMP-dependent protein kinase catalytic subunit - Dictyostelium| discoideum (Slime mold) Length = 648 Score = 160 bits (406), Expect = 2e-38 Identities = 91/312 (29%), Positives = 162/312 (51%), Gaps = 6/312 (1%) Frame = +2 Query: 491 ITTSEGTVEAIQRPQVPLQAPGIAAAFFCVRLPACLPAIMGEQKGNILMHKYEMGKMLGQ 670 I + + + +Q+ Q+ P +FF LP P + ++ + +++ ++LG Sbjct: 295 IRQQQQSQQQLQQQQLQQIPPPTVNSFF---LP---PPVNARER----LKEFKQIRVLGT 344 Query: 671 GTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPNIVQMYEVMA 850 GTF KVY +N + A+K +K V++ + + E S++ + HP IV +Y+ Sbjct: 345 GTFGKVYLIQNTKDGCYYAMKCLNKAYVVQLKQVEHLNSEKSILSSIHHPFIVNLYQAFQ 404 Query: 851 TKTKIYFVLEHVKGGELFNKVQRG-RLKEDAARKYFQQLICAVDFCHSRGVYHRDLKPEN 1027 + K+Y + E+V GGE+F +++ + A+ Y +++ A++F H + + +RDLKPEN Sbjct: 405 DEKKLYLLFEYVAGGEVFTHLRKSMKFSNSTAKFYAAEIVLALEFLHKQNIVYRDLKPEN 464 Query: 1028 LLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKGYDGAKADIWSCG 1207 LL+D ++K++DFG + +R++ T CGTP Y+APE+I KG+ G D W+ G Sbjct: 465 LLIDNQGHIKITDFGFA-----KRVEDRTFTLCGTPEYLAPEIIQSKGH-GKAVDWWALG 518 Query: 1208 VILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXXXDPNPSTRISIEK 1387 +++F ++AGY PF D + +Y KI P F D + + R+ K Sbjct: 519 ILIFEMLAGYPPFYDDDTFAIYNKILAGRITFPLGFDVDAKDLIKRLLTADRTRRLGALK 578 Query: 1388 -----IMEHPWF 1408 + H WF Sbjct: 579 DGALDVKNHRWF 590
>P22612:KAPCG_HUMAN cAMP-dependent protein kinase, gamma-catalytic subunit - Homo sapiens| (Human) Length = 351 Score = 160 bits (406), Expect = 2e-38 Identities = 91/262 (34%), Positives = 145/262 (55%), Gaps = 6/262 (2%) Frame = +2 Query: 641 KYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHP 820 ++E + LG G+F +V R+ ET A+K+ +K+KV+K + I E +++ + P Sbjct: 43 QFERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAIDFP 102 Query: 821 NIVQMYEVMATKTKIYFVLEHVKGGELFNKVQR-GRLKEDAARKYFQQLICAVDFCHSRG 997 +V++ + +Y V+E+V GGE+F+++QR GR E A Y Q++ AV + HS Sbjct: 103 FLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSLD 162 Query: 998 VYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKGYD 1177 + HRDLKPENLL+D+ L+V+DFG + +R+ G T CGTP Y+APE+I KGY+ Sbjct: 163 LIHRDLKPENLLIDQQGYLQVTDFGFA-----KRVKGRTWTLCGTPEYLAPEIILSKGYN 217 Query: 1178 GAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXXXDP 1357 A D W+ GV+++ + G+ PF + +Y+KI + PS SSD Sbjct: 218 KA-VDWWALGVLIYEMAVGFPPFYADQPIQIYEKIVSGRVRFPSKLSSDLKHLLRSLLQV 276 Query: 1358 NPSTRI-----SIEKIMEHPWF 1408 + + R + I H WF Sbjct: 277 DLTKRFGNLRNGVGDIKNHKWF 298
>P05132:KAPCA_MOUSE cAMP-dependent protein kinase, alpha-catalytic subunit - Mus musculus| (Mouse) Length = 351 Score = 160 bits (405), Expect = 2e-38 Identities = 89/264 (33%), Positives = 147/264 (55%), Gaps = 6/264 (2%) Frame = +2 Query: 635 MHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVK 814 + +++ K LG G+F +V ++ E+ A+K+ DK+KV+K + E +++ V Sbjct: 41 LDQFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVN 100 Query: 815 HPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQR-GRLKEDAARKYFQQLICAVDFCHS 991 P +V++ + +Y V+E+V GGE+F+ ++R GR E AR Y Q++ ++ HS Sbjct: 101 FPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHS 160 Query: 992 RGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKG 1171 + +RDLKPENLL+D+ ++V+DFG + +R+ G T CGTP Y+APE+I KG Sbjct: 161 LDLIYRDLKPENLLIDQQGYIQVTDFGFA-----KRVKGRTWTLCGTPEYLAPEIILSKG 215 Query: 1172 YDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXXX 1351 Y+ A D W+ GV+++ + AGY PF + +Y+KI + + PS FSSD Sbjct: 216 YNKA-VDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLL 274 Query: 1352 DPNPSTRI-----SIEKIMEHPWF 1408 + + R + I H WF Sbjct: 275 QVDLTKRFGNLKNGVNDIKNHKWF 298
>Q6PFQ0:KS6A6_DANRE Ribosomal protein S6 kinase alpha-6 - Danio rerio (Zebrafish)| (Brachydanio rerio) Length = 740 Score = 160 bits (404), Expect = 3e-38 Identities = 99/279 (35%), Positives = 156/279 (55%), Gaps = 9/279 (3%) Frame = +2 Query: 641 KYEMGKMLGQGTFAKVYHARNI---ETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLV 811 ++E+ K+LGQG+F KV+ R + + Q A+KV K LK + K E ++ V Sbjct: 66 QFELLKVLGQGSFGKVFLVRKLMGPDAGQLYAMKVLKKAS-LKVRDRVRTKMERDILVEV 124 Query: 812 KHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQRGRL-KEDAARKYFQQLICAVDFCH 988 HP IV+++ T+ K+Y +L+ ++GG++F ++ + + E+ + Y +L A+D H Sbjct: 125 NHPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVMFTEEDVKFYLAELALALDHLH 184 Query: 989 SRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRK 1168 + G+ +RDLKPEN+LLDE ++K++DFGLS E D ++ CGT Y+APEV+NR+ Sbjct: 185 NLGIVYRDLKPENILLDEAGHIKLTDFGLS--KESVDQDKKAYSFCGTVEYMAPEVVNRR 242 Query: 1169 GYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXX 1348 G+ AD WS GV++F ++ G LPFQ K+ I KA+ P + S + Sbjct: 243 GHT-QSADWWSLGVLMFEMLTGTLPFQGKDRNETMNMILKAKLGMPQFLSLEAQGLLRML 301 Query: 1349 XDPNPSTRI-----SIEKIMEHPWFRKGLDAKLLRYNLQ 1450 NPS R+ +E+I H +F KL R LQ Sbjct: 302 FKRNPSNRLGAGPDGVEEIKRHTFFSTIDWNKLYRRELQ 340 Score = 131 bits (330), Expect = 1e-29 Identities = 86/266 (32%), Positives = 139/266 (52%), Gaps = 12/266 (4%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 YE+ + +G G+++ + T+ A+K+ DK K D + +M+ +HPN Sbjct: 420 YELKEDIGVGSYSICKRCIHRVTAMEFAVKIIDKSK------RDPSEEIEILMRYGQHPN 473 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNKVQRGR-LKEDAARKYFQQLICAVDFCHSRGV 1000 I+ + +V +Y V E +KGGEL +K+ R + E A + VD+ H +GV Sbjct: 474 IITLKDVYDEGRFVYLVTELMKGGELLDKILRQKFFSEREASAVLYTITKTVDYLHCQGV 533 Query: 1001 YHRDLKPENLL-LDENSN---LKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRK 1168 HRDLKP N+L +D++ N +++ DFG + + R +GLL T C T +VAPEV+ R+ Sbjct: 534 VHRDLKPSNILYMDDSGNPDSIRICDFGFA--KQLRGDNGLLLTPCYTANFVAPEVLMRQ 591 Query: 1169 GYDGAKADIWSCGVILFVLMAGYLPF---QDKNLMNMYKKIGKAEFKCP--SW--FSSDX 1327 GYD A DIWS GV+L+ ++AGY PF + + +IG +F +W S Sbjct: 592 GYDAA-CDIWSLGVLLYTMLAGYTPFANGPNDTPEEILLRIGSGKFSLSGGNWDSVSDSS 650 Query: 1328 XXXXXXXXDPNPSTRISIEKIMEHPW 1405 +P R + E++++H W Sbjct: 651 KDLLSHMLHVDPHHRYTAEQVLKHSW 676
>P11801:KPSH1_HUMAN Serine/threonine-protein kinase H1 - Homo sapiens (Human)| Length = 424 Score = 160 bits (404), Expect = 3e-38 Identities = 90/263 (34%), Positives = 155/263 (58%), Gaps = 8/263 (3%) Frame = +2 Query: 641 KYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHP 820 KY++ ++G+G+F++V + T Q AIK+ + K +G + + E+ V++ V+H Sbjct: 97 KYDIKALIGRGSFSRVVRVEHRATRQPYAIKMIET-KYREG--REVCESELRVLRRVRHA 153 Query: 821 NIVQMYEVMATKTKIYFVLEHVKGGELFNK-VQRGRLKEDAARKYFQQLICAVDFCHSRG 997 NI+Q+ EV T+ ++Y V+E GGELF++ + +G E A + Q ++ V + H+ G Sbjct: 154 NIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRYLHALG 213 Query: 998 VYHRDLKPENLLL---DENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRK 1168 + HRDLKPENLL +S + ++DFGL++ + + D L+ T+CGTP Y+APEV+ RK Sbjct: 214 ITHRDLKPENLLYYHPGTDSKIIITDFGLASARK-KGDDCLMKTTCGTPEYIAPEVLVRK 272 Query: 1169 GYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKI--GKAEFKCPSW--FSSDXXXX 1336 Y + D+W+ GVI ++L++G +PF+D N +Y++I GK + W S+ Sbjct: 273 PYTNS-VDMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYSYSGEPWPSVSNLAKDF 331 Query: 1337 XXXXXDPNPSTRISIEKIMEHPW 1405 +P R++ + + HPW Sbjct: 332 IDRLLTVDPGARMTALQALRHPW 354
>Q0V7M1:KPSH1_BOVIN Serine/threonine-protein kinase H1 - Bos taurus (Bovine)| Length = 424 Score = 160 bits (404), Expect = 3e-38 Identities = 90/263 (34%), Positives = 155/263 (58%), Gaps = 8/263 (3%) Frame = +2 Query: 641 KYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHP 820 KY++ ++G+G+F++V + T Q AIK+ + K +G + + E+ V++ V+H Sbjct: 97 KYDIKALIGRGSFSRVVRVEHRATRQPYAIKMIET-KYREG--REVCESELRVLRRVRHA 153 Query: 821 NIVQMYEVMATKTKIYFVLEHVKGGELFNK-VQRGRLKEDAARKYFQQLICAVDFCHSRG 997 NI+Q+ EV T+ ++Y V+E GGELF++ + +G E A + Q ++ V + H+ G Sbjct: 154 NIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRYLHALG 213 Query: 998 VYHRDLKPENLLL---DENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRK 1168 + HRDLKPENLL +S + ++DFGL++ + + D L+ T+CGTP Y+APEV+ RK Sbjct: 214 ITHRDLKPENLLYYHPGTDSKIIITDFGLASARK-KGDDCLMKTTCGTPEYIAPEVLVRK 272 Query: 1169 GYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKI--GKAEFKCPSW--FSSDXXXX 1336 Y + D+W+ GVI ++L++G +PF+D N +Y++I GK + W S+ Sbjct: 273 PYTNS-VDMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYSYSGEPWPSVSNLAKDF 331 Query: 1337 XXXXXDPNPSTRISIEKIMEHPW 1405 +P R++ + + HPW Sbjct: 332 IDRLLTVDPGARMTALQALRHPW 354
>P13186:KIN2_YEAST Serine/threonine-protein kinase KIN2 - Saccharomyces cerevisiae| (Baker's yeast) Length = 1147 Score = 160 bits (404), Expect = 3e-38 Identities = 77/220 (35%), Positives = 130/220 (59%), Gaps = 1/220 (0%) Frame = +2 Query: 785 REISVMKLVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKV-QRGRLKEDAARKYFQQ 961 RE S+ +++ HP+I +++E+ Y + E+V GG+L + + Q G LKE ARK+ + Sbjct: 172 REASLGQILYHPHICRLFEMCTMSNHFYMLFEYVSGGQLLDYIIQHGSLKEHHARKFARG 231 Query: 962 LICAVDFCHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAY 1141 + A+ + H+ + HRDLK EN+++ + +K+ DFGLS I + R+ LHT CG+ + Sbjct: 232 IASALQYLHANNIVHRDLKIENIMISSSGEIKIIDFGLSNIFDYRKQ---LHTFCGSLYF 288 Query: 1142 VAPEVINRKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSS 1321 APE++ + Y G + DIWS G++L+VL+ G +PF D+N +++KI K + PS S Sbjct: 289 AAPELLKAQPYTGPEVDIWSFGIVLYVLVCGKVPFDDENSSILHEKIKKGKVDYPSHLSI 348 Query: 1322 DXXXXXXXXXDPNPSTRISIEKIMEHPWFRKGLDAKLLRY 1441 + +P R +++ ++EHPW +G D K Y Sbjct: 349 EVISLLTRMIVVDPLRRATLKNVVEHPWMNRGYDFKAPSY 388
>P27791:KAPCA_RAT cAMP-dependent protein kinase, alpha-catalytic subunit - Rattus| norvegicus (Rat) Length = 351 Score = 159 bits (403), Expect = 3e-38 Identities = 89/257 (34%), Positives = 143/257 (55%), Gaps = 6/257 (2%) Frame = +2 Query: 656 KMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPNIVQM 835 K LG G+F +V ++ E+ A+K+ DK+KV+K + E +++ V P +V++ Sbjct: 48 KTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKL 107 Query: 836 YEVMATKTKIYFVLEHVKGGELFNKVQR-GRLKEDAARKYFQQLICAVDFCHSRGVYHRD 1012 + +Y V+E+V GGE+F+ ++R GR E AR Y Q++ ++ HS + +RD Sbjct: 108 EFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRD 167 Query: 1013 LKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKGYDGAKAD 1192 LKPENLL+D+ ++V+DFG + +R+ G T CGTP Y+APE+I KGY+ A D Sbjct: 168 LKPENLLIDQQGYIQVTDFGFA-----KRVKGRTWTLCGTPEYLAPEIILSKGYNKA-VD 221 Query: 1193 IWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXXXDPNPSTR 1372 W+ GV+++ + AGY PF + +Y+KI + + PS FSSD + + R Sbjct: 222 WWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKR 281 Query: 1373 I-----SIEKIMEHPWF 1408 + I H WF Sbjct: 282 FGNLKNGVNDIKNHKWF 298
>Q683C9:AUR2_ARATH Serine/threonine-protein kinase Aurora-2 - Arabidopsis thaliana| (Mouse-ear cress) Length = 282 Score = 159 bits (403), Expect = 3e-38 Identities = 86/263 (32%), Positives = 143/263 (54%), Gaps = 3/263 (1%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 +++GK LG+G F VY AR + VA+KV K ++ + + Q++RE+ + ++HPN Sbjct: 19 FDIGKPLGRGKFGHVYLAREKRSDHIVALKVLFKAQLQQSQVEHQLRREVEIQSHLRHPN 78 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNKVQRGR-LKEDAARKYFQQLICAVDFCHSRGV 1000 I+++Y + ++Y +LE+ GEL+ ++Q+ + E A Y L A+ +CH + V Sbjct: 79 ILRLYGYFYDQKRVYLILEYAVRGELYKELQKCKYFSERRAATYVASLARALIYCHGKHV 138 Query: 1001 YHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKGYDG 1180 HRD+KPENLL+ LK++DFG S + RR T CGT Y+ PE++ +D Sbjct: 139 IHRDIKPENLLIGAQGELKIADFGWSVHTFNRR-----RTMCGTLDYLPPEMVESVEHD- 192 Query: 1181 AKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCP--SWFSSDXXXXXXXXXD 1354 A DIWS G++ + + G PF+ + YK+I + + K P SS Sbjct: 193 ASVDIWSLGILCYEFLYGVPPFEAREHSETYKRIVQVDLKFPPKPIVSSSAKDLISQMLV 252 Query: 1355 PNPSTRISIEKIMEHPWFRKGLD 1423 + R+++ K++EHPW + D Sbjct: 253 KESTQRLALHKLLEHPWIVQNAD 275
>Q91YA2:KPSH1_MOUSE Serine/threonine-protein kinase H1 - Mus musculus (Mouse)| Length = 424 Score = 159 bits (402), Expect = 5e-38 Identities = 90/263 (34%), Positives = 155/263 (58%), Gaps = 8/263 (3%) Frame = +2 Query: 641 KYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHP 820 KY++ ++G+G+F++V + T Q AIK+ + K +G + + E+ V++ V+H Sbjct: 97 KYDIKALIGRGSFSRVVRVEHRATRQPYAIKMIET-KYREG--REVCESELRVLRRVRHA 153 Query: 821 NIVQMYEVMATKTKIYFVLEHVKGGELFNK-VQRGRLKEDAARKYFQQLICAVDFCHSRG 997 NI+Q+ EV T+ ++Y V+E GGELF++ + +G E A + Q ++ V + H+ G Sbjct: 154 NIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRYLHALG 213 Query: 998 VYHRDLKPENLLL---DENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRK 1168 + HRDLKPENLL +S + ++DFGL++ + + D L+ T+CGTP Y+APEV+ RK Sbjct: 214 ITHRDLKPENLLYYHPGTDSKIIITDFGLASARK-KGDDCLMKTTCGTPEYIAPEVLVRK 272 Query: 1169 GYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKI--GKAEFKCPSW--FSSDXXXX 1336 Y + D+W+ GVI ++L++G +PF+D N +Y++I GK + W S+ Sbjct: 273 PYTNS-VDMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYSYLGEPWPSVSNLAKDF 331 Query: 1337 XXXXXDPNPSTRISIEKIMEHPW 1405 +P R++ + + HPW Sbjct: 332 IDRLLTVDPGARMTALQALRHPW 354
>P18654:KS6A3_MOUSE Ribosomal protein S6 kinase alpha-3 - Mus musculus (Mouse)| Length = 740 Score = 159 bits (401), Expect = 6e-38 Identities = 95/265 (35%), Positives = 152/265 (57%), Gaps = 9/265 (3%) Frame = +2 Query: 641 KYEMGKMLGQGTFAKVYHARNIETS---QSVAIKVTDKEKVLKGGLTDQIKREISVMKLV 811 ++E+ K+LGQG+F KV+ + I S Q A+KV K+ LK + K E ++ V Sbjct: 67 QFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVL-KKATLKVRDRVRTKMERDILVEV 125 Query: 812 KHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQRGRL-KEDAARKYFQQLICAVDFCH 988 HP IV+++ T+ K+Y +L+ ++GG+LF ++ + + E+ + Y +L A+D H Sbjct: 126 NHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLH 185 Query: 989 SRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRK 1168 S G+ +RDLKPEN+LLDE ++K++DFGLS E + ++ CGT Y+APEV+NR+ Sbjct: 186 SLGIIYRDLKPENILLDEEGHIKLTDFGLS--KESIDHEKKAYSFCGTVEYMAPEVVNRR 243 Query: 1169 GYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXX 1348 G+ AD WS GV++F ++ G LPFQ K+ I KA+ P + S + Sbjct: 244 GHT-QSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQSLLRML 302 Query: 1349 XDPNPSTRI-----SIEKIMEHPWF 1408 NP+ R+ +E+I H +F Sbjct: 303 FKRNPANRLGAGPDGVEEIKRHSFF 327 Score = 135 bits (339), Expect = 9e-31 Identities = 89/285 (31%), Positives = 145/285 (50%), Gaps = 12/285 (4%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 YE+ + +G G+++ + T+ A+K+ DK K D + +++ +HPN Sbjct: 422 YEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKSK------RDPTEEIEILLRYGQHPN 475 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNKVQRGRL-KEDAARKYFQQLICAVDFCHSRGV 1000 I+ + +V +Y V E +KGGEL +K+ R + E A + V++ H++GV Sbjct: 476 IITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGV 535 Query: 1001 YHRDLKPENLL-LDENSN---LKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRK 1168 HRDLKP N+L +DE+ N +++ DFG + + R +GLL T C T +VAPEV+ R+ Sbjct: 536 VHRDLKPSNILYVDESGNPESIRICDFGFA--KQLRAENGLLMTPCYTANFVAPEVLKRQ 593 Query: 1169 GYDGAKADIWSCGVILFVLMAGYLPF---QDKNLMNMYKKIGKAEFKCPSWF----SSDX 1327 GYD A DIWS GV+L+ ++ GY PF D + +IG +F + S Sbjct: 594 GYDAA-CDIWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTA 652 Query: 1328 XXXXXXXXDPNPSTRISIEKIMEHPWFRKGLDAKLLRYNLQAKDA 1462 +P R++ ++ HPW +L +Y L +DA Sbjct: 653 KDLVSKMLHVDPHQRLTAALVLRHPWIVHW--DQLPQYQLNRQDA 695
>P51812:KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 - Homo sapiens (Human)| Length = 740 Score = 159 bits (401), Expect = 6e-38 Identities = 95/265 (35%), Positives = 152/265 (57%), Gaps = 9/265 (3%) Frame = +2 Query: 641 KYEMGKMLGQGTFAKVYHARNIETS---QSVAIKVTDKEKVLKGGLTDQIKREISVMKLV 811 ++E+ K+LGQG+F KV+ + I S Q A+KV K+ LK + K E ++ V Sbjct: 67 QFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVL-KKATLKVRDRVRTKMERDILVEV 125 Query: 812 KHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQRGRL-KEDAARKYFQQLICAVDFCH 988 HP IV+++ T+ K+Y +L+ ++GG+LF ++ + + E+ + Y +L A+D H Sbjct: 126 NHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLH 185 Query: 989 SRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRK 1168 S G+ +RDLKPEN+LLDE ++K++DFGLS E + ++ CGT Y+APEV+NR+ Sbjct: 186 SLGIIYRDLKPENILLDEEGHIKLTDFGLS--KESIDHEKKAYSFCGTVEYMAPEVVNRR 243 Query: 1169 GYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXX 1348 G+ AD WS GV++F ++ G LPFQ K+ I KA+ P + S + Sbjct: 244 GHT-QSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQSLLRML 302 Query: 1349 XDPNPSTRI-----SIEKIMEHPWF 1408 NP+ R+ +E+I H +F Sbjct: 303 FKRNPANRLGAGPDGVEEIKRHSFF 327 Score = 135 bits (339), Expect = 9e-31 Identities = 89/285 (31%), Positives = 145/285 (50%), Gaps = 12/285 (4%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 YE+ + +G G+++ + T+ A+K+ DK K D + +++ +HPN Sbjct: 422 YEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKSK------RDPTEEIEILLRYGQHPN 475 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNKVQRGRL-KEDAARKYFQQLICAVDFCHSRGV 1000 I+ + +V +Y V E +KGGEL +K+ R + E A + V++ H++GV Sbjct: 476 IITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGV 535 Query: 1001 YHRDLKPENLL-LDENSN---LKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRK 1168 HRDLKP N+L +DE+ N +++ DFG + + R +GLL T C T +VAPEV+ R+ Sbjct: 536 VHRDLKPSNILYVDESGNPESIRICDFGFA--KQLRAENGLLMTPCYTANFVAPEVLKRQ 593 Query: 1169 GYDGAKADIWSCGVILFVLMAGYLPF---QDKNLMNMYKKIGKAEFKCPSWF----SSDX 1327 GYD A DIWS GV+L+ ++ GY PF D + +IG +F + S Sbjct: 594 GYDAA-CDIWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTA 652 Query: 1328 XXXXXXXXDPNPSTRISIEKIMEHPWFRKGLDAKLLRYNLQAKDA 1462 +P R++ ++ HPW +L +Y L +DA Sbjct: 653 KDLVSKMLHVDPHQRLTAALVLRHPWIVHW--DQLPQYQLNRQDA 695
>Q09170:CDS1_SCHPO Serine/threonine-protein kinase cds1 - Schizosaccharomyces pombe| (Fission yeast) Length = 460 Score = 159 bits (401), Expect = 6e-38 Identities = 90/270 (33%), Positives = 146/270 (54%), Gaps = 15/270 (5%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVL----KGGLTDQIKREISVMKLV 811 YE+ + LG GTFA V A + + + AIK+ +K K+L + T+ +REI ++K + Sbjct: 167 YEIIRTLGSGTFAVVKLAVEVNSGKWYAIKIINKRKILLTSSEKRATEMFQREIDILKSL 226 Query: 812 KHPNIVQMYEVMATKTKIYFVLEHVKGGELFN-KVQRGRLKEDAARKYFQQLICAVDFCH 988 HP +VQ +E+ +++ V+E+V+GG+L + + G + E + +QL+ + H Sbjct: 227 HHPGVVQCHEIFENDDELFIVMEYVEGGDLMDFLIANGSIDEQDCKPLLKQLLETLLHLH 286 Query: 989 SRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRK 1168 +GV HRD+KPEN+L+ + +LK+SDFGL+ + L T CGT Y+APEV+ K Sbjct: 287 KQGVTHRDIKPENILITNDFHLKISDFGLAKV--IHGTGTFLETFCGTMGYLAPEVLKSK 344 Query: 1169 ------GYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFK----CPSWFS 1318 GYD K DIWS G +L+V++ +PF + + I K + + S Sbjct: 345 NVNLDGGYDD-KVDIWSLGCVLYVMLTASIPFASSSQAKCIELISKGAYPIEPLLENEIS 403 Query: 1319 SDXXXXXXXXXDPNPSTRISIEKIMEHPWF 1408 + + NP RIS + ++HPWF Sbjct: 404 EEGIDLINRMLEINPEKRISESEALQHPWF 433
>Q5ZKI0:KCC2D_CHICK Calcium/calmodulin-dependent protein kinase type II delta chain -| Gallus gallus (Chicken) Length = 479 Score = 158 bits (400), Expect = 8e-38 Identities = 93/263 (35%), Positives = 148/263 (56%), Gaps = 8/263 (3%) Frame = +2 Query: 641 KYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHP 820 +Y++ + LG+G F+ V I T Q A K+ + +K L +++RE + +L+KHP Sbjct: 13 EYQLFEELGKGAFSVVRRCMKITTGQEYAAKIINTKK-LSARDHQKLEREARICRLLKHP 71 Query: 821 NIVQMYEVMATKTKIYFVLEHVKGGELFNK-VQRGRLKEDAARKYFQQLICAVDFCHSRG 997 NIV++++ ++ + Y V + V GGELF V R E A QQ++ +V+ CH G Sbjct: 72 NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNG 131 Query: 998 VYHRDLKPENLLLDENSN---LKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRK 1168 + HRDLKPENLLL S +K++DFGL+ E + GTP Y++PEV+ + Sbjct: 132 IVHRDLKPENLLLASKSKGAAVKLADFGLAI--EVQGEQQAWFGFAGTPGYLSPEVLRKD 189 Query: 1169 GYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKI--GKAEFKCPSW--FSSDXXXX 1336 Y G D+W+CGVIL++L+ GY PF D++ +Y++I G +F P W + + Sbjct: 190 PY-GKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDL 248 Query: 1337 XXXXXDPNPSTRISIEKIMEHPW 1405 NP+ RI+ + ++HPW Sbjct: 249 INKMLTINPAKRITASEALKHPW 271
>P15791:KCC2D_RAT Calcium/calmodulin-dependent protein kinase type II delta chain -| Rattus norvegicus (Rat) Length = 533 Score = 158 bits (399), Expect = 1e-37 Identities = 93/263 (35%), Positives = 148/263 (56%), Gaps = 8/263 (3%) Frame = +2 Query: 641 KYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHP 820 +Y++ + LG+G F+ V I T Q A K+ + +K L +++RE + +L+KHP Sbjct: 13 EYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKK-LSARDHQKLEREARICRLLKHP 71 Query: 821 NIVQMYEVMATKTKIYFVLEHVKGGELFNK-VQRGRLKEDAARKYFQQLICAVDFCHSRG 997 NIV++++ ++ + Y V + V GGELF V R E A QQ++ +V+ CH G Sbjct: 72 NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNG 131 Query: 998 VYHRDLKPENLLLDENSN---LKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRK 1168 + HRDLKPENLLL S +K++DFGL+ E + GTP Y++PEV+ + Sbjct: 132 IVHRDLKPENLLLASKSKGAAVKLADFGLAI--EVQGDQQAWFGFAGTPGYLSPEVLRKD 189 Query: 1169 GYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKI--GKAEFKCPSW--FSSDXXXX 1336 Y G D+W+CGVIL++L+ GY PF D++ +Y++I G +F P W + + Sbjct: 190 PY-GKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDL 248 Query: 1337 XXXXXDPNPSTRISIEKIMEHPW 1405 NP+ RI+ + ++HPW Sbjct: 249 INKMLTINPAKRITASEALKHPW 271
>O77708:KCC2D_RABIT Calcium/calmodulin-dependent protein kinase type II delta chain -| Oryctolagus cuniculus (Rabbit) Length = 533 Score = 158 bits (399), Expect = 1e-37 Identities = 93/263 (35%), Positives = 148/263 (56%), Gaps = 8/263 (3%) Frame = +2 Query: 641 KYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHP 820 +Y++ + LG+G F+ V I T Q A K+ + +K L +++RE + +L+KHP Sbjct: 13 EYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKK-LSARDHQKLEREARICRLLKHP 71 Query: 821 NIVQMYEVMATKTKIYFVLEHVKGGELFNK-VQRGRLKEDAARKYFQQLICAVDFCHSRG 997 NIV++++ ++ + Y V + V GGELF V R E A QQ++ +V+ CH G Sbjct: 72 NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNG 131 Query: 998 VYHRDLKPENLLLDENSN---LKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRK 1168 + HRDLKPENLLL S +K++DFGL+ E + GTP Y++PEV+ + Sbjct: 132 IVHRDLKPENLLLASKSKGAAVKLADFGLAI--EVQGDQQAWFGFAGTPGYLSPEVLRKD 189 Query: 1169 GYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKI--GKAEFKCPSW--FSSDXXXX 1336 Y G D+W+CGVIL++L+ GY PF D++ +Y++I G +F P W + + Sbjct: 190 PY-GKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDL 248 Query: 1337 XXXXXDPNPSTRISIEKIMEHPW 1405 NP+ RI+ + ++HPW Sbjct: 249 INKMLTINPAKRITASEALKHPW 271
>Q95266:KCC2D_PIG Calcium/calmodulin-dependent protein kinase type II delta chain - Sus| scrofa (Pig) Length = 499 Score = 158 bits (399), Expect = 1e-37 Identities = 93/263 (35%), Positives = 148/263 (56%), Gaps = 8/263 (3%) Frame = +2 Query: 641 KYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHP 820 +Y++ + LG+G F+ V I T Q A K+ + +K L +++RE + +L+KHP Sbjct: 13 EYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKK-LSARDHQKLEREARICRLLKHP 71 Query: 821 NIVQMYEVMATKTKIYFVLEHVKGGELFNK-VQRGRLKEDAARKYFQQLICAVDFCHSRG 997 NIV++++ ++ + Y V + V GGELF V R E A QQ++ +V+ CH G Sbjct: 72 NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNG 131 Query: 998 VYHRDLKPENLLLDENSN---LKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRK 1168 + HRDLKPENLLL S +K++DFGL+ E + GTP Y++PEV+ + Sbjct: 132 IVHRDLKPENLLLASKSKGAAVKLADFGLAI--EVQGDQQAWFGFAGTPGYLSPEVLRKD 189 Query: 1169 GYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKI--GKAEFKCPSW--FSSDXXXX 1336 Y G D+W+CGVIL++L+ GY PF D++ +Y++I G +F P W + + Sbjct: 190 PY-GKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDL 248 Query: 1337 XXXXXDPNPSTRISIEKIMEHPW 1405 NP+ RI+ + ++HPW Sbjct: 249 INKMLTINPAKRITASEALKHPW 271
>Q6PHZ2:KCC2D_MOUSE Calcium/calmodulin-dependent protein kinase type II delta chain - Mus| musculus (Mouse) Length = 499 Score = 158 bits (399), Expect = 1e-37 Identities = 93/263 (35%), Positives = 148/263 (56%), Gaps = 8/263 (3%) Frame = +2 Query: 641 KYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHP 820 +Y++ + LG+G F+ V I T Q A K+ + +K L +++RE + +L+KHP Sbjct: 13 EYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKK-LSARDHQKLEREARICRLLKHP 71 Query: 821 NIVQMYEVMATKTKIYFVLEHVKGGELFNK-VQRGRLKEDAARKYFQQLICAVDFCHSRG 997 NIV++++ ++ + Y V + V GGELF V R E A QQ++ +V+ CH G Sbjct: 72 NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNG 131 Query: 998 VYHRDLKPENLLLDENSN---LKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRK 1168 + HRDLKPENLLL S +K++DFGL+ E + GTP Y++PEV+ + Sbjct: 132 IVHRDLKPENLLLASKSKGAAVKLADFGLAI--EVQGDQQAWFGFAGTPGYLSPEVLRKD 189 Query: 1169 GYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKI--GKAEFKCPSW--FSSDXXXX 1336 Y G D+W+CGVIL++L+ GY PF D++ +Y++I G +F P W + + Sbjct: 190 PY-GKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDL 248 Query: 1337 XXXXXDPNPSTRISIEKIMEHPW 1405 NP+ RI+ + ++HPW Sbjct: 249 INKMLTINPAKRITASEALKHPW 271
>Q13557:KCC2D_HUMAN Calcium/calmodulin-dependent protein kinase type II delta chain -| Homo sapiens (Human) Length = 499 Score = 158 bits (399), Expect = 1e-37 Identities = 93/263 (35%), Positives = 148/263 (56%), Gaps = 8/263 (3%) Frame = +2 Query: 641 KYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHP 820 +Y++ + LG+G F+ V I T Q A K+ + +K L +++RE + +L+KHP Sbjct: 13 EYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKK-LSARDHQKLEREARICRLLKHP 71 Query: 821 NIVQMYEVMATKTKIYFVLEHVKGGELFNK-VQRGRLKEDAARKYFQQLICAVDFCHSRG 997 NIV++++ ++ + Y V + V GGELF V R E A QQ++ +V+ CH G Sbjct: 72 NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNG 131 Query: 998 VYHRDLKPENLLLDENSN---LKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRK 1168 + HRDLKPENLLL S +K++DFGL+ E + GTP Y++PEV+ + Sbjct: 132 IVHRDLKPENLLLASKSKGAAVKLADFGLAI--EVQGDQQAWFGFAGTPGYLSPEVLRKD 189 Query: 1169 GYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKI--GKAEFKCPSW--FSSDXXXX 1336 Y G D+W+CGVIL++L+ GY PF D++ +Y++I G +F P W + + Sbjct: 190 PY-GKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDL 248 Query: 1337 XXXXXDPNPSTRISIEKIMEHPW 1405 NP+ RI+ + ++HPW Sbjct: 249 INKMLTINPAKRITASEALKHPW 271
>Q2HJF7:KCC2D_BOVIN Calcium/calmodulin-dependent protein kinase type II delta chain - Bos| taurus (Bovine) Length = 488 Score = 158 bits (399), Expect = 1e-37 Identities = 93/263 (35%), Positives = 148/263 (56%), Gaps = 8/263 (3%) Frame = +2 Query: 641 KYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHP 820 +Y++ + LG+G F+ V I T Q A K+ + +K L +++RE + +L+KHP Sbjct: 13 EYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKK-LSARDHQKLEREARICRLLKHP 71 Query: 821 NIVQMYEVMATKTKIYFVLEHVKGGELFNK-VQRGRLKEDAARKYFQQLICAVDFCHSRG 997 NIV++++ ++ + Y V + V GGELF V R E A QQ++ +V+ CH G Sbjct: 72 NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNG 131 Query: 998 VYHRDLKPENLLLDENSN---LKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRK 1168 + HRDLKPENLLL S +K++DFGL+ E + GTP Y++PEV+ + Sbjct: 132 IVHRDLKPENLLLASKSKGAAVKLADFGLAI--EVQGDQQAWFGFAGTPGYLSPEVLRKD 189 Query: 1169 GYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKI--GKAEFKCPSW--FSSDXXXX 1336 Y G D+W+CGVIL++L+ GY PF D++ +Y++I G +F P W + + Sbjct: 190 PY-GKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDL 248 Query: 1337 XXXXXDPNPSTRISIEKIMEHPW 1405 NP+ RI+ + ++HPW Sbjct: 249 INKMLTINPAKRITASEALKHPW 271
>Q91604:STK11_XENLA Serine/threonine-protein kinase 11 - Xenopus laevis (African clawed| frog) Length = 432 Score = 157 bits (398), Expect = 1e-37 Identities = 89/268 (33%), Positives = 149/268 (55%), Gaps = 7/268 (2%) Frame = +2 Query: 632 LMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKV--LKGGLTDQIKREISVMK 805 L+ KY MG +LG+G++ KV + +T A+K+ K+K+ + G + +K+EI +++ Sbjct: 48 LVGKYLMGDLLGEGSYGKVKEMLDSDTLCRRAVKILKKKKLRRIPNGEAN-VKKEIQLLR 106 Query: 806 LVKHPNIVQMYEVMAT--KTKIYFVLEHVKGG--ELFNKVQRGRLKEDAARKYFQQLICA 973 ++H N++Q+ +V+ K K+Y V+E+ G E+ + VQ A YF QLI Sbjct: 107 RLRHRNVIQLVDVLYNEEKQKMYMVMEYCVCGMQEMLDSVQDKHFPVFQAHGYFCQLIDG 166 Query: 974 VDFCHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPE 1153 +++ HS+G+ H+D+KP NLLL + LK+SD G++ TS G+PA+ PE Sbjct: 167 LEYLHSQGIVHKDIKPGNLLLTTDGTLKISDLGVAEALHPFAEGDTCRTSQGSPAFQPPE 226 Query: 1154 VIN-RKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXX 1330 + N + G K DIWS GV L+ + G PF+ N+ +++ IGK ++ P Sbjct: 227 IANGLDTFSGFKVDIWSAGVTLYNITTGLYPFEGDNIYKLFENIGKGDYSIPEECGPLLS 286 Query: 1331 XXXXXXXDPNPSTRISIEKIMEHPWFRK 1414 + +P+ R SI++I +H WFRK Sbjct: 287 DLLRGMLEYDPAKRFSIQQIRQHNWFRK 314
>Q9M077:AUR1_ARATH Serine/threonine-protein kinase Aurora-1 - Arabidopsis thaliana| (Mouse-ear cress) Length = 294 Score = 157 bits (398), Expect = 1e-37 Identities = 85/263 (32%), Positives = 142/263 (53%), Gaps = 3/263 (1%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 +++GK LG+G F VY AR ++ VA+KV K ++ + + Q++RE+ + ++HPN Sbjct: 31 FDIGKPLGRGKFGHVYLAREKRSNHVVALKVLFKSQLQQSQVEHQLRREVEIQSHLRHPN 90 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNKVQRGR-LKEDAARKYFQQLICAVDFCHSRGV 1000 I+++Y + ++Y +LE+ GEL+ +Q+ + E A Y L A+ +CH + V Sbjct: 91 ILRLYGYFYDQKRVYLILEYAARGELYKDLQKCKYFSERRAATYVASLARALIYCHGKHV 150 Query: 1001 YHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKGYDG 1180 HRD+KPENLL+ LK++DFG S + RR T CGT Y+ PE++ +D Sbjct: 151 IHRDIKPENLLIGAQGELKIADFGWSVHTFNRR-----RTMCGTLDYLPPEMVESVEHD- 204 Query: 1181 AKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCP--SWFSSDXXXXXXXXXD 1354 A DIWS G++ + + G PF+ + Y++I + + K P S+ Sbjct: 205 ASVDIWSLGILCYEFLYGVPPFEAMEHSDTYRRIVQVDLKFPPKPIISASAKDLISQMLV 264 Query: 1355 PNPSTRISIEKIMEHPWFRKGLD 1423 S R+ + K++EHPW + D Sbjct: 265 KESSQRLPLHKLLEHPWIVQNAD 287
>P18652:KS6AA_CHICK Ribosomal protein S6 kinase 2 alpha - Gallus gallus (Chicken)| Length = 752 Score = 157 bits (397), Expect = 2e-37 Identities = 92/265 (34%), Positives = 154/265 (58%), Gaps = 9/265 (3%) Frame = +2 Query: 641 KYEMGKMLGQGTFAKVYHARNI---ETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLV 811 ++E+ K+LGQG+F KV+ R I +++ A+KV K+ LK + K E ++ V Sbjct: 79 QFELLKVLGQGSFGKVFLVRKITPPDSNHLYAMKVL-KKATLKVRDRVRTKIERDILADV 137 Query: 812 KHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQRGRL-KEDAARKYFQQLICAVDFCH 988 HP +V+++ T+ K+Y +L+ ++GG+LF ++ + + E+ + Y +L +D H Sbjct: 138 NHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLH 197 Query: 989 SRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRK 1168 S G+ +RDLKPEN+LLDE ++K++DFGLS E + ++ CGT Y+APEV+NR+ Sbjct: 198 SLGIIYRDLKPENILLDEEGHIKLTDFGLS--KEAIDHEKKAYSFCGTVEYMAPEVVNRQ 255 Query: 1169 GYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXX 1348 G+ + AD WS GV++F ++ G LPFQ K+ I KA+ P + S++ Sbjct: 256 GHSHS-ADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSAEAQSLLRAL 314 Query: 1349 XDPNPSTRI-----SIEKIMEHPWF 1408 NP+ R+ E+I HP++ Sbjct: 315 FKRNPANRLGSGPDGAEEIKRHPFY 339 Score = 129 bits (324), Expect = 5e-29 Identities = 83/266 (31%), Positives = 139/266 (52%), Gaps = 12/266 (4%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 Y + + +G G+++ + T+ A+KV DK K D + +++ +HPN Sbjct: 435 YVVKEAIGVGSYSVCKRCIHKTTNMEYAVKVIDKSK------RDPSEEIEILLRYGQHPN 488 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNKVQRGRLKEDAARKYFQQLIC-AVDFCHSRGV 1000 I+ + +V +Y V E ++GGEL +K+ R + + IC V++ HS+GV Sbjct: 489 IITLKDVYDDGKYVYLVTELMRGGELLDKILRQKFFSEREASSVLHTICKTVEYLHSQGV 548 Query: 1001 YHRDLKPENLL-LDENSN---LKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRK 1168 HRDLKP N+L +DE+ N +++ DFG + + R +GLL T C T +VAPEV+ R+ Sbjct: 549 VHRDLKPSNILYVDESGNPESIRICDFGFA--KQLRAENGLLMTPCYTANFVAPEVLKRQ 606 Query: 1169 GYDGAKADIWSCGVILFVLMAGYLPFQD---KNLMNMYKKIGKAEFKC--PSW--FSSDX 1327 GYD DIWS GV+L+ ++AG PF + + +IG +F +W S Sbjct: 607 GYDEG-CDIWSLGVLLYTMLAGCTPFANGPSDTPEEILTRIGGGKFSVNGGNWDTISDVA 665 Query: 1328 XXXXXXXXDPNPSTRISIEKIMEHPW 1405 +P R++ +++++HPW Sbjct: 666 KDLVSKMLHVDPHQRLTAKQVLQHPW 691
>P21137:KAPC_CAEEL cAMP-dependent protein kinase catalytic subunit - Caenorhabditis| elegans Length = 404 Score = 157 bits (397), Expect = 2e-37 Identities = 88/257 (34%), Positives = 141/257 (54%), Gaps = 6/257 (2%) Frame = +2 Query: 656 KMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPNIVQM 835 K LG G+F +V ++ ++ A+K+ DK+KV+K + E +++ + P +V M Sbjct: 85 KTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAIDFPFLVNM 144 Query: 836 YEVMATKTKIYFVLEHVKGGELFNKVQR-GRLKEDAARKYFQQLICAVDFCHSRGVYHRD 1012 + +Y VLE + GGE+F+ ++R GR E +R Y Q++ A ++ HS + +RD Sbjct: 145 TFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRD 204 Query: 1013 LKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKGYDGAKAD 1192 LKPENLL+D LK++DFG + +R+ G T CGTP Y+APE+I KGY+ A D Sbjct: 205 LKPENLLIDSTGYLKITDFGFA-----KRVKGRTWTLCGTPEYLAPEIILSKGYNKA-VD 258 Query: 1193 IWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXXXDPNPSTR 1372 W+ GV+++ + AGY PF + +Y+KI + K PS FS++ + + R Sbjct: 259 WWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVKFPSHFSNELKDLLKNLLQVDLTKR 318 Query: 1373 I-----SIEKIMEHPWF 1408 + I H WF Sbjct: 319 YGNLKNGVADIKNHKWF 335
>P28582:CDPK_DAUCA Calcium-dependent protein kinase - Daucus carota (Carrot)| Length = 532 Score = 157 bits (397), Expect = 2e-37 Identities = 100/272 (36%), Positives = 151/272 (55%), Gaps = 10/272 (3%) Frame = +2 Query: 641 KYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMK-LVKH 817 KY +GK LG+G F VY + Q A K K K++ + IKREI +++ L Sbjct: 80 KYTLGKELGRGQFGCVYQCTENSSGQLYACKSILKRKLVSKNDKEDIKREIQILQHLSGQ 139 Query: 818 PNIVQMYEVMATKTKIYFVLEHVKGGELFNKV-QRGRLKEDAARKYFQQLICAVDFCHSR 994 PNIV+ V + ++ V+E GGELF+++ +G E AA +Q++ V CH Sbjct: 140 PNIVEFKGVFEDRQSVHLVMELCAGGELFDRIIAQGHYSERAAATICRQIVNVVHVCHFM 199 Query: 995 GVYHRDLKPENLLL---DENSNLKVSDFGLSTISECRRLDGLLHTS-CGTPAYVAPEVIN 1162 GV HRDLKPEN LL D+++ LK +DFGLS E +G ++ + G+ YVAPEV+ Sbjct: 200 GVMHRDLKPENFLLSSKDKDAMLKATDFGLSVFIE----EGKVYRNIVGSAYYVAPEVL- 254 Query: 1163 RKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKI--GKAEFKCPSW--FSSDXX 1330 R+ Y G + DIWS GVIL++L++G PF +N ++ I G +F+ W S+ Sbjct: 255 RRSY-GKEIDIWSAGVILYILLSGVPPFWAENEKGIFDAILEGVIDFESEPWPSVSNSAK 313 Query: 1331 XXXXXXXDPNPSTRISIEKIMEHPWFRKGLDA 1426 +P RI+ ++++HPW R+G +A Sbjct: 314 DLVRKMLTQDPRRRITSAQVLDHPWMREGGEA 345
>O15865:CDPK2_PLAFK Calcium-dependent protein kinase 2 - Plasmodium falciparum (isolate| K1 / Thailand) Length = 513 Score = 157 bits (397), Expect = 2e-37 Identities = 105/279 (37%), Positives = 148/279 (53%), Gaps = 15/279 (5%) Frame = +2 Query: 614 EQKGNILMH------KYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTD 775 E+K IL H KY + + LGQGT+ VY + T+Q AIK K+++ + Sbjct: 56 ERKNLILCHSGKLEDKYIIDEKLGQGTYGCVYKGIDKVTNQLYAIKEEKKDRLKN---IN 112 Query: 776 QIKREISVMKLVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNK-VQRGRLKEDAARKY 952 + +EI +MK + HPNIV++YE IY ++E G ELF+ ++ G E A Sbjct: 113 RFFQEIEIMKKLDHPNIVKLYETYENDNYIYLIMELCSGRELFDSIIENGSFTEKNAATI 172 Query: 953 FQQLICAVDFCHSRGVYHRDLKPENLLL---DENSNLKVSDFGLSTISECRRLDGLLHTS 1123 +Q+ A+ + HS + HRDLKPEN L +++S LK+ DFGL S+ T Sbjct: 173 MKQIFSAIFYLHSLNIVHRDLKPENFLFQSENKDSLLKIIDFGL---SKNLGTGEFTTTK 229 Query: 1124 CGTPAYVAPEVINRKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKC 1303 GTP YVAP+V++ K YD K DIWS GVI++ L+ GY PF + KK+ K EF C Sbjct: 230 AGTPYYVAPQVLDGK-YD-KKCDIWSSGVIMYTLLCGYPPFYGDTDNEVLKKVKKGEF-C 286 Query: 1304 ---PSW--FSSDXXXXXXXXXDPNPSTRISIEKIMEHPW 1405 W SSD NP+ R +IE+ + HPW Sbjct: 287 FYENDWGSISSDAKNLITKLLTYNPNERCTIEEALNHPW 325
>Q8ICR0:CDPK2_PLAF7 Calcium-dependent protein kinase 2 - Plasmodium falciparum (isolate| 3D7) Length = 509 Score = 157 bits (397), Expect = 2e-37 Identities = 105/279 (37%), Positives = 148/279 (53%), Gaps = 15/279 (5%) Frame = +2 Query: 614 EQKGNILMH------KYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTD 775 E+K IL H KY + + LGQGT+ VY + T+Q AIK K+++ + Sbjct: 56 ERKNLILCHSGKLEDKYIIDEKLGQGTYGCVYKGIDKVTNQLYAIKEEKKDRLKN---IN 112 Query: 776 QIKREISVMKLVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNK-VQRGRLKEDAARKY 952 + +EI +MK + HPNIV++YE IY ++E G ELF+ ++ G E A Sbjct: 113 RFFQEIEIMKKLDHPNIVKLYETYENDNYIYLIMELCSGRELFDSIIENGSFTEKNAATI 172 Query: 953 FQQLICAVDFCHSRGVYHRDLKPENLLL---DENSNLKVSDFGLSTISECRRLDGLLHTS 1123 +Q+ A+ + HS + HRDLKPEN L +++S LK+ DFGL S+ T Sbjct: 173 MKQIFSAIFYLHSLNIVHRDLKPENFLFQSENKDSLLKIIDFGL---SKNLGTGEFTTTK 229 Query: 1124 CGTPAYVAPEVINRKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKC 1303 GTP YVAP+V++ K YD K DIWS GVI++ L+ GY PF + KK+ K EF C Sbjct: 230 AGTPYYVAPQVLDGK-YD-KKCDIWSSGVIMYTLLCGYPPFYGDTDNEVLKKVKKGEF-C 286 Query: 1304 ---PSW--FSSDXXXXXXXXXDPNPSTRISIEKIMEHPW 1405 W SSD NP+ R +IE+ + HPW Sbjct: 287 FYENDWGSISSDAKNLITKLLTYNPNERCTIEEALNHPW 325
>P38147:CHK1_YEAST Serine/threonine-protein kinase CHK1 - Saccharomyces cerevisiae| (Baker's yeast) Length = 527 Score = 157 bits (396), Expect = 2e-37 Identities = 96/266 (36%), Positives = 155/266 (58%), Gaps = 14/266 (5%) Frame = +2 Query: 650 MGKMLGQGTFAKVYHAR-NIETSQSVAIKVTDKEKVLKGGLTDQ-IKREISVM-KLVKHP 820 +G +GQG FA V +A ++ S +A+K K GL+D+ I +E+ + K KHP Sbjct: 17 LGDTVGQGAFACVKNAHLQMDPSIILAVKFIHVPTCKKMGLSDKDITKEVVLQSKCSKHP 76 Query: 821 NIVQMYEVMATKTKIYFVLEHVKGGELFNKVQRG-RLKEDAARKYFQQLICAVDFCHSR- 994 N++++ + +K ++ +LE GG+LF+K++ + D A+ YFQQL+ A+++ H Sbjct: 77 NVLRLIDCNVSKEYMWIILEMADGGDLFDKIEPDVGVDSDVAQFYFQQLVSAINYLHVEC 136 Query: 995 GVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSC---GTPAYVAPEVI-N 1162 GV HRD+KPEN+LLD+N NLK++DFGL+ S+ RR DG L S G+P Y+APEV+ + Sbjct: 137 GVAHRDIKPENILLDKNGNLKLADFGLA--SQFRRKDGTLRVSMDQRGSPPYMAPEVLYS 194 Query: 1163 RKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMN-----MYKKIGKAEFKCPSWFSSDX 1327 +GY + DIWS G++LFVL+ G P++ +L N + G + S Sbjct: 195 EEGYYADRTDIWSIGILLFVLLTGQTPWELPSLENEDFVFFIENDGNLNWGPWSKIEFTH 254 Query: 1328 XXXXXXXXDPNPSTRISIEKIMEHPW 1405 P+P+ R++++ + HPW Sbjct: 255 LNLLRKILQPDPNKRVTLKALKLHPW 280
>P28583:CDPK_SOYBN Calcium-dependent protein kinase SK5 - Glycine max (Soybean)| Length = 508 Score = 157 bits (396), Expect = 2e-37 Identities = 96/272 (35%), Positives = 148/272 (54%), Gaps = 9/272 (3%) Frame = +2 Query: 617 QKGNILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREIS 796 Q+ + YE+G+ LGQG F + + A K K K+L + + REI Sbjct: 25 QRTQNIREVYEVGRKLGQGQFGTTFECTRRASGGKFACKSIPKRKLLCKEDYEDVWREIQ 84 Query: 797 VMK-LVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNK-VQRGRLKEDAARKYFQQLIC 970 +M L +H N+V++ T ++ V+E +GGELF++ VQ+G E A + + ++ Sbjct: 85 IMHHLSEHANVVRIEGTYEDSTAVHLVMELCEGGELFDRIVQKGHYSERQAARLIKTIVE 144 Query: 971 AVDFCHSRGVYHRDLKPENLL---LDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAY 1141 V+ CHS GV HRDLKPEN L +DE++ LK +DFGLS + G+P Y Sbjct: 145 VVEACHSLGVMHRDLKPENFLFDTIDEDAKLKATDFGLSVF---YKPGESFCDVVGSPYY 201 Query: 1142 VAPEVINRKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKI--GKAEFKCPSW- 1312 VAPEV+ RK Y G ++D+WS GVIL++L++G PF ++ ++++I GK +F W Sbjct: 202 VAPEVL-RKLY-GPESDVWSAGVILYILLSGVPPFWAESEPGIFRQILLGKLDFHSEPWP 259 Query: 1313 -FSSDXXXXXXXXXDPNPSTRISIEKIMEHPW 1405 S D NP TR++ +++ HPW Sbjct: 260 SISDSAKDLIRKMLDQNPKTRLTAHEVLRHPW 291
>Q9VKN7:AURKB_DROME Serine/threonine-protein kinase Ial - Drosophila melanogaster (Fruit| fly) Length = 329 Score = 157 bits (396), Expect = 2e-37 Identities = 92/270 (34%), Positives = 142/270 (52%), Gaps = 5/270 (1%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 +EMG LG+G F +VY AR + VA+KV KE++ KG + Q+ REI + +KHP+ Sbjct: 53 FEMGAHLGRGKFGRVYLARERHSHYLVAMKVMFKEELRKGCVQRQVLREIEIQSRLKHPH 112 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNKVQ---RGRLKEDAARKYFQQLICAVDFCHSR 994 I+++ +++IY LE GELF ++ R E + KY Q+ A+++CH Sbjct: 113 ILRLLTWFHDESRIYLALEIASEGELFKHLRGAPNHRFDEPRSAKYTYQVANALNYCHLN 172 Query: 995 GVYHRDLKPENLLLDENSNLKVSDFGLS--TISECRRLDGLLHTSCGTPAYVAPEVINRK 1168 V HRDLKPEN+LL +LK++DFG S T + RR T CGT Y+ PE+++ Sbjct: 173 NVIHRDLKPENILLTSTDDLKLADFGWSAHTPNNKRR------TLCGTLDYLPPEMVDGN 226 Query: 1169 GYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXX 1348 YD + D W G++ + + G PF+ + + Y KI + E PS S Sbjct: 227 SYDDS-VDQWCLGILCYEFVVGCPPFESNSTESTYSKIRRMEISYPSHLSKGCKELIGGL 285 Query: 1349 XDPNPSTRISIEKIMEHPWFRKGLDAKLLR 1438 RI++ +M H W + G+ + L+ Sbjct: 286 LRKESKGRITLVDVMTHYWVKAGMAERELQ 315
>P53351:PLK2_MOUSE Serine/threonine-protein kinase PLK2 - Mus musculus (Mouse)| Length = 682 Score = 156 bits (395), Expect = 3e-37 Identities = 86/263 (32%), Positives = 144/263 (54%), Gaps = 4/263 (1%) Frame = +2 Query: 641 KYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHP 820 +Y GK+LG+G FAK Y ++ ++ A K+ +V K ++I +EI + +L+ H Sbjct: 78 RYCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQREKIDKEIELHRLLHHK 137 Query: 821 NIVQMYEVMATKTKIYFVLEHVKGGELFNKVQ-RGRLKEDAARKYFQQLICAVDFCHSRG 997 ++VQ Y K IY +LE+ + + ++ R L E R Y +Q++ + + H + Sbjct: 138 HVVQFYHYFEDKENIYILLEYCSRRSMAHILKARKVLTEPEVRYYLRQIVSGLKYLHEQE 197 Query: 998 VYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLH---TSCGTPAYVAPEVINRK 1168 + HRDLK N ++E LKV DFGL+ RL+ L H T CGTP Y++PEV+N++ Sbjct: 198 ILHRDLKLGNFFINEAMELKVGDFGLAA-----RLEPLEHRRRTICGTPNYLSPEVLNKQ 252 Query: 1169 GYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXX 1348 G+ G ++DIW+ G +++ ++ G PF+ NL Y+ I +A + PS + Sbjct: 253 GH-GCESDIWALGCVMYTMLLGRPPFETTNLKETYRCIREARYTMPSSLLAPAKHLIASM 311 Query: 1349 XDPNPSTRISIEKIMEHPWFRKG 1417 NP R S++ I+ H +F +G Sbjct: 312 LSKNPEDRPSLDDIIRHDFFLQG 334
>P39009:DUN1_YEAST DNA damage response protein kinase DUN1 - Saccharomyces cerevisiae| (Baker's yeast) Length = 513 Score = 156 bits (395), Expect = 3e-37 Identities = 108/361 (29%), Positives = 178/361 (49%), Gaps = 41/361 (11%) Frame = +2 Query: 449 CTMGFDVASQPSS*ITTSEGTV-----------EAIQRPQVPLQAPGIAAAFFCVRLPAC 595 C+ F AS S+ I + V E ++PQ+ + A +R Sbjct: 131 CSFLFKYASSSSTDIENDDEKVSSESRSYKNDDEVFKKPQISATSSQNATTSAAIRK--- 187 Query: 596 LPAIMGEQKGNILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTD 775 + + + KY +GK LG G +A V A+N +T Q VA+K+ ++ Sbjct: 188 ----LNKTRPVSFFDKYLLGKELGAGHYALVKEAKNKKTGQQVAVKIFHAQQNDDQKKNK 243 Query: 776 QIKREISVMKLVKHPNIVQMYE-----VMATKTKIYFVLEHVKGGELFNKVQRGR-LKED 937 Q + E +++ V+HPNIV + + + ++ + Y VLE + GELF ++ R L++D Sbjct: 244 QFREETNILMRVQHPNIVNLLDSFVEPISKSQIQKYLVLEKIDDGELFERIVRKTCLRQD 303 Query: 938 AARKYFQQLICAVDFCHSRGVYHRDLKPENLLL----------------DENS---NLKV 1060 ++ F+QL+ + + H + + HRD+KPEN+LL DE+ +K+ Sbjct: 304 ESKALFKQLLTGLKYLHEQNIIHRDIKPENILLNITRRENPSQVQLGPWDEDEIDIQVKI 363 Query: 1061 SDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKGYDGAKADIWSCGVILFVLMAGYL 1240 +DFGL+ + + +T CGTP+YVAPEV+ +KGY +K D+WS GVIL+V + G+ Sbjct: 364 ADFGLAKFTGEMQ---FTNTLCGTPSYVAPEVLTKKGYT-SKVDLWSAGVILYVCLCGFP 419 Query: 1241 PFQDK-NLMNMYKKI--GKAEFKCPSWFSSD--XXXXXXXXXDPNPSTRISIEKIMEHPW 1405 PF D+ ++ ++I K F P W D NP R +I++ + HPW Sbjct: 420 PFSDQLGPPSLKEQILQAKYAFYSPYWDKIDDSVLHLISNLLVLNPDERYNIDEALNHPW 479 Query: 1406 F 1408 F Sbjct: 480 F 480
>Q12152:YP150_YEAST Putative serine/threonine-protein kinase YPL150W - Saccharomyces| cerevisiae (Baker's yeast) Length = 901 Score = 156 bits (394), Expect = 4e-37 Identities = 95/258 (36%), Positives = 139/258 (53%), Gaps = 2/258 (0%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 Y++ K +G+G+F KVY A + T + V +K +DK I RE+ + P Sbjct: 41 YKILKQIGEGSFGKVYLALHRPTHRKVCLKTSDKND-------PNIVREVFYHRQFDFPY 93 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNKV-QRGRLKEDAARKYFQQLICAVDFCHSRGV 1000 I ++YEV+ T++K++ LE+ G EL++ + R+ + F Q+ AV + HS Sbjct: 94 ITKLYEVIVTESKVWMALEYCPGKELYDHLLSLRRISLLECGELFAQISGAVYYAHSMHC 153 Query: 1001 YHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKGYDG 1180 HRDLK EN+LLD+N N K++DFG + EC L T CGT Y+APE+I R+ YDG Sbjct: 154 VHRDLKLENILLDKNGNAKLTDFGFTR--ECMTKT-TLETVCGTTVYMAPELIERRTYDG 210 Query: 1181 AKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPS-WFSSDXXXXXXXXXDP 1357 K DIWS GVIL+ L+ GYLPF D + KI E K + D Sbjct: 211 FKIDIWSLGVILYTLITGYLPFDDDDEAKTKWKIVNEEPKYDAKVIPDDARDLISRLLAK 270 Query: 1358 NPSTRISIEKIMEHPWFR 1411 NP R S+ +++ HP+ + Sbjct: 271 NPGERPSLSQVLRHPFLQ 288
>Q9Z265:CHK2_MOUSE Serine/threonine-protein kinase Chk2 - Mus musculus (Mouse)| Length = 546 Score = 156 bits (394), Expect = 4e-37 Identities = 100/276 (36%), Positives = 149/276 (53%), Gaps = 16/276 (5%) Frame = +2 Query: 632 LMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTD-----QIKREIS 796 L +Y M K LG G +V A +T Q VAIK+ K + G + ++ EI Sbjct: 220 LRDEYIMSKTLGSGACGEVKMAFERKTCQKVAIKIISKRRFALGSSREADTAPSVETEIE 279 Query: 797 VMKLVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQRG-RLKEDAARKYFQQLICA 973 ++K + HP I+++ +V + Y VLE ++GGELF++V RLKE + YF Q++ A Sbjct: 280 ILKKLNHPCIIKIKDVFDAED-YYIVLELMEGGELFDRVVGNKRLKEATCKLYFYQMLVA 338 Query: 974 VDFCHSRGVYHRDLKPENLLL---DENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYV 1144 V + H G+ HRDLKPEN+LL +E+ +K++DFG S I L+ T CGTP Y+ Sbjct: 339 VQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGQSKI---LGETSLMRTLCGTPTYL 395 Query: 1145 APEVINRKGYDG--AKADIWSCGVILFVLMAGYLPFQD-KNLMNMYKKI--GKAEFKCPS 1309 APEV+ G G D WS GVILF+ ++GY PF + K +++ +I GK F Sbjct: 396 APEVLVSNGTAGYSRAVDCWSLGVILFICLSGYPPFSEHKTQVSLKDQITSGKYNFIPEV 455 Query: 1310 W--FSSDXXXXXXXXXDPNPSTRISIEKIMEHPWFR 1411 W S + +P R++ E+ + HPW + Sbjct: 456 WTDVSEEALDLVKKLLVVDPKARLTTEEALNHPWLQ 491
>Q9R012:PLK2_RAT Serine/threonine-protein kinase PLK2 - Rattus norvegicus (Rat)| Length = 682 Score = 155 bits (393), Expect = 5e-37 Identities = 85/263 (32%), Positives = 144/263 (54%), Gaps = 4/263 (1%) Frame = +2 Query: 641 KYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHP 820 +Y GK+LG+G FAK Y ++ ++ A K+ +V K ++I +EI + +++ H Sbjct: 78 RYCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQREKIDKEIELHRILHHK 137 Query: 821 NIVQMYEVMATKTKIYFVLEHVKGGELFNKVQ-RGRLKEDAARKYFQQLICAVDFCHSRG 997 ++VQ Y K IY +LE+ + + ++ R L E R Y +Q++ + + H + Sbjct: 138 HVVQFYHYFEDKENIYILLEYCSRRSMAHILKARKVLTEPEVRYYLRQIVSGLKYLHEQE 197 Query: 998 VYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLH---TSCGTPAYVAPEVINRK 1168 + HRDLK N ++E LKV DFGL+ RL+ L H T CGTP Y++PEV+N++ Sbjct: 198 ILHRDLKLGNFFINEAMELKVGDFGLAA-----RLEPLEHRRRTICGTPNYLSPEVLNKQ 252 Query: 1169 GYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXX 1348 G+ G ++DIW+ G +++ ++ G PF+ NL Y+ I +A + PS + Sbjct: 253 GH-GCESDIWALGCVMYTMLLGRPPFETTNLKETYRCIREARYTMPSSLLAPAKHLIASM 311 Query: 1349 XDPNPSTRISIEKIMEHPWFRKG 1417 NP R S++ I+ H +F +G Sbjct: 312 LSKNPEDRPSLDDIIRHDFFLQG 334
>Q5R4L1:PLK2_PONPY Serine/threonine-protein kinase PLK2 - Pongo pygmaeus (Orangutan)| Length = 685 Score = 155 bits (393), Expect = 5e-37 Identities = 85/263 (32%), Positives = 144/263 (54%), Gaps = 4/263 (1%) Frame = +2 Query: 641 KYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHP 820 +Y GK+LG+G FAK Y ++ ++ A K+ +V K ++I +EI + +++ H Sbjct: 81 RYCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQREKIDKEIELHRILHHK 140 Query: 821 NIVQMYEVMATKTKIYFVLEHVKGGELFNKVQ-RGRLKEDAARKYFQQLICAVDFCHSRG 997 ++VQ Y K IY +LE+ + + ++ R L E R Y +Q++ + + H + Sbjct: 141 HVVQFYHYFEDKENIYILLEYCSRRSMAHILKARKVLTEPEVRYYLRQIVSGLKYLHEQE 200 Query: 998 VYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLH---TSCGTPAYVAPEVINRK 1168 + HRDLK N ++E LKV DFGL+ RL+ L H T CGTP Y++PEV+N++ Sbjct: 201 ILHRDLKLGNFFINEAMELKVGDFGLAA-----RLEPLEHRRRTICGTPNYLSPEVLNKQ 255 Query: 1169 GYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXX 1348 G+ G ++DIW+ G +++ ++ G PF+ NL Y+ I +A + PS + Sbjct: 256 GH-GCESDIWALGCVMYTMLLGRPPFETTNLKETYRCIREARYTMPSSLLAPAKHLIASM 314 Query: 1349 XDPNPSTRISIEKIMEHPWFRKG 1417 NP R S++ I+ H +F +G Sbjct: 315 LSKNPEDRPSLDDIIRHDFFLQG 337
>Q9NYY3:PLK2_HUMAN Serine/threonine-protein kinase PLK2 - Homo sapiens (Human)| Length = 685 Score = 155 bits (393), Expect = 5e-37 Identities = 85/263 (32%), Positives = 144/263 (54%), Gaps = 4/263 (1%) Frame = +2 Query: 641 KYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHP 820 +Y GK+LG+G FAK Y ++ ++ A K+ +V K ++I +EI + +++ H Sbjct: 81 RYCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQREKIDKEIELHRILHHK 140 Query: 821 NIVQMYEVMATKTKIYFVLEHVKGGELFNKVQ-RGRLKEDAARKYFQQLICAVDFCHSRG 997 ++VQ Y K IY +LE+ + + ++ R L E R Y +Q++ + + H + Sbjct: 141 HVVQFYHYFEDKENIYILLEYCSRRSMAHILKARKVLTEPEVRYYLRQIVSGLKYLHEQE 200 Query: 998 VYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLH---TSCGTPAYVAPEVINRK 1168 + HRDLK N ++E LKV DFGL+ RL+ L H T CGTP Y++PEV+N++ Sbjct: 201 ILHRDLKLGNFFINEAMELKVGDFGLAA-----RLEPLEHRRRTICGTPNYLSPEVLNKQ 255 Query: 1169 GYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXX 1348 G+ G ++DIW+ G +++ ++ G PF+ NL Y+ I +A + PS + Sbjct: 256 GH-GCESDIWALGCVMYTMLLGRPPFETTNLKETYRCIREARYTMPSSLLAPAKHLIASM 314 Query: 1349 XDPNPSTRISIEKIMEHPWFRKG 1417 NP R S++ I+ H +F +G Sbjct: 315 LSKNPEDRPSLDDIIRHDFFLQG 337
>Q16975:KPC2_APLCA Calcium-independent protein kinase C - Aplysia californica| (California sea hare) Length = 743 Score = 155 bits (393), Expect = 5e-37 Identities = 90/278 (32%), Positives = 149/278 (53%), Gaps = 9/278 (3%) Frame = +2 Query: 629 ILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKL 808 I +H + K+LG+G+F KV A T + AIKV K+ +++ + E ++ L Sbjct: 398 ISLHDFNFIKVLGKGSFGKVMLAEKKGTDEVYAIKVLKKDVIIQDDDVECTMTEKRILAL 457 Query: 809 -VKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQRGR-LKEDAARKYFQQLICAVDF 982 KHP + ++ TK +++FV+E+V GG+L ++QR R E AR Y ++ A+ F Sbjct: 458 SAKHPFLTALHSSFQTKERLFFVMEYVNGGDLMFQIQRARKFDEPRARFYAAEVTLALMF 517 Query: 983 CHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVIN 1162 H G+ +RDLK +N+LLD + K++DFG+ E + L T CGTP Y+APE++ Sbjct: 518 LHRHGIIYRDLKLDNILLDAEGHCKIADFGM--CKEGMTENKLTQTFCGTPDYIAPEILQ 575 Query: 1163 RKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXX 1342 YD A D W+ GV+++ +MAG PF+ N ++++ I + P W S + Sbjct: 576 ELKYD-ASVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDDVLYPVWLSKEAVSILK 634 Query: 1343 XXXDPNPSTRISI-------EKIMEHPWFRKGLDAKLL 1435 NP+ R+ + I+ HP+F + +D + L Sbjct: 635 GFMTKNPAKRLGCVTTQGCEKAILVHPFFHEKIDWEAL 672
>P34208:CHK1_SCHPO Serine/threonine-protein kinase chk1 - Schizosaccharomyces pombe| (Fission yeast) Length = 496 Score = 155 bits (393), Expect = 5e-37 Identities = 93/266 (34%), Positives = 146/266 (54%), Gaps = 12/266 (4%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLK----GGLTDQIKREISVMKLV 811 Y +G+ +G G FA V + + ++ A+K +K+ G ++ EI + KL Sbjct: 10 YHIGREIGTGAFASVRLCYD-DNAKIYAVKFVNKKHATSCMNAGVWARRMASEIQLHKLC 68 Query: 812 K-HPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQRG-RLKEDAARKYFQQLICAVDFC 985 H NI+ Y + VLE +GG+LF+K++ + ED A+ YF QL+ + F Sbjct: 69 NGHKNIIHFYNTAENPQWRWVVLEFAQGGDLFDKIEPDVGIDEDVAQFYFAQLMEGISFM 128 Query: 986 HSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINR 1165 HS+GV HRDLKPEN+LLD N NLK+SDFG +++ + LL++ G+P Y APE+ + Sbjct: 129 HSKGVAHRDLKPENILLDYNGNLKISDFGFASLFSYKGKSRLLNSPVGSPPYAAPEITQQ 188 Query: 1166 KGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMN-----MYKK-IGKAEFKCPSWFSSDX 1327 YDG+K D+WSCG+ILF L+ G P+ D+ + N +YKK + + + S Sbjct: 189 --YDGSKVDVWSCGIILFALLLGNTPW-DEAISNTGDYLLYKKQCERPSYHPWNLLSPGA 245 Query: 1328 XXXXXXXXDPNPSTRISIEKIMEHPW 1405 +P R S++ +++HPW Sbjct: 246 YSIITGMLRSDPFKRYSVKHVVQHPW 271
>Q0VD22:STK33_BOVIN Serine/threonine-protein kinase 33 - Bos taurus (Bovine)| Length = 486 Score = 155 bits (392), Expect = 7e-37 Identities = 95/276 (34%), Positives = 152/276 (55%), Gaps = 15/276 (5%) Frame = +2 Query: 623 GNILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVM 802 G L Y G++LGQG+F V A + E AIK +KEK + ++RE+ ++ Sbjct: 109 GAALQEIYTFGRILGQGSFGMVIEAIDKERETKWAIKKVNKEKAGSSAVK-LLEREVDIL 167 Query: 803 KLVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQR-GRLKEDAARKYFQQLICAVD 979 K VKH +I+ + +V T K+Y V+E + GEL ++R G E+ R Q L A+ Sbjct: 168 KSVKHEHIIHLEQVFETPKKMYLVMELCEDGELKEILERKGHFSENETRWIIQSLASAIA 227 Query: 980 FCHSRGVYHRDLKPENLLL---------DENSNLKVSDFGLSTISECRRLDGLLHTSCGT 1132 + H++ + HRDLK EN+++ + N N+KV+DFGL+ + + R + +L T+CGT Sbjct: 228 YLHNKDIVHRDLKLENIMVKSSFIDANNEMNLNIKVTDFGLA-VKKHGRSEVMLQTTCGT 286 Query: 1133 PAYVAPEVINRKGYDGAKADIWSCGVILFVLMAGYLPF---QDKNLMNMYKKIGKAEFKC 1303 P Y+APEVIN Y + DIWS GVI+++L+ G PF ++ L + KK G+ FK Sbjct: 287 PIYMAPEVINAHDY-SQQCDIWSIGVIMYILLCGKAPFMASSEEKLFELIKK-GELHFKN 344 Query: 1304 PSW--FSSDXXXXXXXXXDPNPSTRISIEKIMEHPW 1405 W S +P+ RI+ ++++++ W Sbjct: 345 SIWNSISDCAKSVLKQLMKVDPAHRITAKELLDNQW 380
>Q6SA08:TSSK4_HUMAN Testis-specific serine/threonine-protein kinase 4 - Homo sapiens| (Human) Length = 328 Score = 155 bits (391), Expect = 9e-37 Identities = 81/229 (35%), Positives = 127/229 (55%), Gaps = 14/229 (6%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 YE+GK +G G++ VY A + VA+K+ K+K L + REI VMK+++H Sbjct: 25 YEVGKAIGHGSYGSVYEAFYTKQKVMVAVKIISKKKASDDYLNKFLPREIQVMKVLRHKY 84 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNKVQR-GRLKEDAARKYFQQLICAVDFCHSRGV 1000 ++ Y + + +++Y +LE +GG++ +QR G E A K+F QL + + HS+ + Sbjct: 85 LINFYRAIESTSRVYIILELAQGGDVLEWIQRYGACSEPLAGKWFSQLTLGIAYLHSKSI 144 Query: 1001 YHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDG-------------LLHTSCGTPAY 1141 HRDLK ENLLLD+ N+K+SDFG + + + G L T CG+ AY Sbjct: 145 VHRDLKLENLLLDKWENVKISDFGFAKMVPSNQPVGCSPSYRQVNCFSHLSQTYCGSFAY 204 Query: 1142 VAPEVINRKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGK 1288 PE++ Y+ +D WS GVIL+ L+ +LPF D NL + ++ K Sbjct: 205 ACPEILRGLPYNPFLSDTWSMGVILYTLVVAHLPFDDTNLKKLLRETQK 253
>Q9UK32:KS6A6_HUMAN Ribosomal protein S6 kinase alpha-6 - Homo sapiens (Human)| Length = 745 Score = 155 bits (391), Expect = 9e-37 Identities = 93/263 (35%), Positives = 150/263 (57%), Gaps = 7/263 (2%) Frame = +2 Query: 641 KYEMGKMLGQGTFAKVYHARNI---ETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLV 811 ++E+ K+LGQG+F KV+ R + Q A+KV K LK + K E ++ V Sbjct: 72 QFELLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKAS-LKVRDRVRTKMERDILVEV 130 Query: 812 KHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQRGRL-KEDAARKYFQQLICAVDFCH 988 HP IV+++ T+ K+Y +L+ ++GG++F ++ + L E+ + Y +L A+D H Sbjct: 131 NHPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVLFTEEDVKFYLAELALALDHLH 190 Query: 989 SRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRK 1168 G+ +RDLKPEN+LLDE ++K++DFGLS E + ++ CGT Y+APEV+NR+ Sbjct: 191 QLGIVYRDLKPENILLDEIGHIKLTDFGLS--KESVDQEKKAYSFCGTVEYMAPEVVNRR 248 Query: 1169 GYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXX 1348 G+ AD WS GV++F ++ G LPFQ K+ I KA+ P + S++ Sbjct: 249 GH-SQSADWWSYGVLMFEMLTGTLPFQGKDRNETMNMILKAKLGMPQFLSAEAQSLLRML 307 Query: 1349 XDPNPSTRI---SIEKIMEHPWF 1408 NP+ R+ +E+I H +F Sbjct: 308 FKRNPANRLGSEGVEEIKRHLFF 330 Score = 127 bits (319), Expect = 2e-28 Identities = 82/266 (30%), Positives = 139/266 (52%), Gaps = 12/266 (4%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 YE+ + +G G+++ + T+ A+K+ DK K D + +M+ +HPN Sbjct: 426 YELKEDIGVGSYSVCKRCIHATTNMEFAVKIIDKSK------RDPSEEIEILMRYGQHPN 479 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNKVQRGR-LKEDAARKYFQQLICAVDFCHSRGV 1000 I+ + +V +Y V + +KGGEL +++ + + E A + VD+ H +GV Sbjct: 480 IITLKDVFDDGRYVYLVTDLMKGGELLDRILKQKCFSEREASDILYVISKTVDYLHCQGV 539 Query: 1001 YHRDLKPENLL-LDENS---NLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRK 1168 HRDLKP N+L +DE++ ++++ DFG + + R +GLL T C T +VAPEV+ ++ Sbjct: 540 VHRDLKPSNILYMDESASADSIRICDFGFA--KQLRGENGLLLTPCYTANFVAPEVLMQQ 597 Query: 1169 GYDGAKADIWSCGVILFVLMAGYLPF---QDKNLMNMYKKIGKAEFKCP--SW--FSSDX 1327 GYD A DIWS GV+ + ++AGY PF + + +IG +F +W S Sbjct: 598 GYDAA-CDIWSLGVLFYTMLAGYTPFANGPNDTPEEILLRIGNGKFSLSGGNWDNISDGA 656 Query: 1328 XXXXXXXXDPNPSTRISIEKIMEHPW 1405 +P R + E+I++H W Sbjct: 657 KDLLSHMLHMDPHQRYTAEQILKHSW 682
>Q6FV07:IPL1_CANGA Spindle assembly checkpoint kinase - Candida glabrata (Yeast)| (Torulopsis glabrata) Length = 358 Score = 155 bits (391), Expect = 9e-37 Identities = 80/258 (31%), Positives = 143/258 (55%), Gaps = 1/258 (0%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 +E+G+ LG+G F KVY R+ ++ A+K +K ++L+ L Q+KRE+ + + HPN Sbjct: 100 FEVGRKLGKGKFGKVYCVRHKKSGFICALKAIEKNEILQFNLLKQLKREVDIQLGMDHPN 159 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNKVQ-RGRLKEDAARKYFQQLICAVDFCHSRGV 1000 I+++Y + ++Y ++EH GEL+ ++ G + A Y Q+ A+ + H + + Sbjct: 160 IIKLYAHFHDEKRVYLLMEHSINGELYKSLKNNGPFNDVLASHYIYQIADALHYMHKKRI 219 Query: 1001 YHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKGYDG 1180 HRD+KPEN+L+ ++ +K++DFG S ++ T CGT Y++PE+I + YD Sbjct: 220 IHRDVKPENVLIGFDNVVKLADFGWSILNP---EGSKRKTLCGTIDYLSPEMITPREYD- 275 Query: 1181 AKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXXXDPN 1360 + D+W+ GV+ + L+ G PF++ + YK+I K + P S D + Sbjct: 276 EQVDVWALGVLAYELVVGVPPFEENSKELTYKRILKCDLNFPESISKDAKDLISKLLVTD 335 Query: 1361 PSTRISIEKIMEHPWFRK 1414 + R+S+ + HPW K Sbjct: 336 TTQRLSLTGVKTHPWILK 353
>P10665:KS6AA_XENLA Ribosomal protein S6 kinase 2 alpha - Xenopus laevis (African clawed| frog) Length = 733 Score = 154 bits (390), Expect = 1e-36 Identities = 92/260 (35%), Positives = 149/260 (57%), Gaps = 9/260 (3%) Frame = +2 Query: 656 KMLGQGTFAKVYHARNI---ETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPNI 826 K+LGQG+F KV+ R I + +Q A+KV K+ LK + K E ++ V HP + Sbjct: 66 KVLGQGSFGKVFLVRKITPPDANQLYAMKVL-KKATLKVRDRVRTKMERDILADVHHPFV 124 Query: 827 VQMYEVMATKTKIYFVLEHVKGGELFNKVQRGRL-KEDAARKYFQQLICAVDFCHSRGVY 1003 V+++ T+ K+Y +L+ ++GG+LF ++ + + E+ + Y +L +D HS G+ Sbjct: 125 VRLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHSLGII 184 Query: 1004 HRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKGYDGA 1183 +RDLKPEN+LLDE ++K++DFGLS E + ++ CGT Y+APEV+NR+G+ + Sbjct: 185 YRDLKPENILLDEEGHIKLTDFGLS--KEAIDHEKKAYSFCGTVEYMAPEVVNRQGHSHS 242 Query: 1184 KADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXXXDPNP 1363 AD WS GV++F ++ G LPFQ K+ I KA+ P + S++ NP Sbjct: 243 -ADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSNEAQSLLRALFKRNP 301 Query: 1364 STRI-----SIEKIMEHPWF 1408 + R+ E+I P+F Sbjct: 302 TNRLGSAMEGAEEIKRQPFF 321 Score = 128 bits (322), Expect = 9e-29 Identities = 85/289 (29%), Positives = 144/289 (49%), Gaps = 13/289 (4%) Frame = +2 Query: 587 PACLPAIMGEQKGNILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGG 766 P L K + M Y + + +G G+++ + T+ A+KV DK K Sbjct: 397 PPVLSVPKTHSKNILFMDVYTVRETIGVGSYSVCKRCVHKGTNMEYAVKVIDKTK----- 451 Query: 767 LTDQIKREISVMKLV-KHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQRGRLKEDAA 943 EI +++ +HPNI+ + +V IY V E ++GGEL +++ R + + Sbjct: 452 --RDPSEEIEILRRYGQHPNIIALKDVYKEGNSIYVVTELMRGGELLDRILRQKFFSERE 509 Query: 944 RKYFQQLIC-AVDFCHSRGVYHRDLKPENLLLDENS----NLKVSDFGLSTISECRRLDG 1108 +C V+ HS+GV HRDLKP N+L + S ++++ DFG + + R +G Sbjct: 510 ASSVLFTVCKTVENLHSQGVVHRDLKPSNILYVDESGDPESIRICDFGFA--KQLRADNG 567 Query: 1109 LLHTSCGTPAYVAPEVINRKGYDGAKADIWSCGVILFVLMAGYLPFQD---KNLMNMYKK 1279 LL T C T +VAPEV+ R+GYD DIWS G++L+ ++AGY PF + + + Sbjct: 568 LLMTPCYTANFVAPEVLKRQGYDEG-CDIWSLGILLYTMLAGYTPFANGLGDTPEEILAR 626 Query: 1280 IGKAEF--KCPSW--FSSDXXXXXXXXXDPNPSTRISIEKIMEHPWFRK 1414 IG +F + +W S+ +P R++ +++++H W K Sbjct: 627 IGSGKFTLRGGNWNTVSAAAKDLVSRMLHVDPHKRLTAKQVLQHEWITK 675
>Q96RR4:KKCC2_HUMAN Calcium/calmodulin-dependent protein kinase kinase 2 - Homo sapiens| (Human) Length = 588 Score = 154 bits (390), Expect = 1e-36 Identities = 99/340 (29%), Positives = 167/340 (49%), Gaps = 29/340 (8%) Frame = +2 Query: 473 SQPSS*ITTSEGTVEAIQRPQVPLQAPGIAAAFFCVRLPACLPAIMGEQKGNILMHKYEM 652 S P S +++ + + +RP V I CV+L ++Y + Sbjct: 125 SLPYSPVSSPQSSPRLPRRPTVESHHVSITGMQDCVQL-----------------NQYTL 167 Query: 653 GKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKG----------------------- 763 +G+G++ V A N + A+KV K+K+++ Sbjct: 168 KDEIGKGSYGVVKLAYNENDNTYYAMKVLSKKKLIRQAGFPRRPPPRGTRPAPGGCIQPR 227 Query: 764 GLTDQIKREISVMKLVKHPNIVQMYEVM--ATKTKIYFVLEHVKGGELFNKVQRGRLKED 937 G +Q+ +EI+++K + HPN+V++ EV+ + +Y V E V G + L ED Sbjct: 228 GPIEQVYQEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGPVMEVPTLKPLSED 287 Query: 938 AARKYFQQLICAVDFCHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLH 1117 AR YFQ LI +++ H + + HRD+KP NLL+ E+ ++K++DFG+S +E + D LL Sbjct: 288 QARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVS--NEFKGSDALLS 345 Query: 1118 TSCGTPAYVAPEVIN--RKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKA 1291 + GTPA++APE ++ RK + G D+W+ GV L+ + G PF D+ +M ++ KI Sbjct: 346 NTVGTPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIKSQ 405 Query: 1292 EFKCPSW--FSSDXXXXXXXXXDPNPSTRISIEKIMEHPW 1405 + P + D D NP +RI + +I HPW Sbjct: 406 ALEFPDQPDIAEDLKDLITRMLDKNPESRIVVPEIKLHPW 445
>P13185:KIN1_YEAST Protein kinase KIN1 - Saccharomyces cerevisiae (Baker's yeast)| Length = 1064 Score = 154 bits (390), Expect = 1e-36 Identities = 84/287 (29%), Positives = 156/287 (54%), Gaps = 27/287 (9%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTD--------KEKVLKGGLTDQ------- 778 +E + +G G+ KV A++ T++ A+K+ + KE++L +Q Sbjct: 120 WEFVETVGAGSMGKVKLAKHRYTNEVCAVKIVNRATKAFLHKEQMLPPPKNEQDVLERQK 179 Query: 779 -----------IKREISVMKLVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKV-QRG 922 RE S+ +++ HP+I +++E+ Y + E+V GG+L + + Q G Sbjct: 180 KLEKEISRDKRTIREASLGQILYHPHICRLFEMCTLSNHFYMLFEYVSGGQLLDYIIQHG 239 Query: 923 RLKEDAARKYFQQLICAVDFCHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRL 1102 ++E ARK+ + + A+ + H+ + HRDLK EN+++ ++S +K+ DFGLS I + R+ Sbjct: 240 SIREHQARKFARGIASALIYLHANNIVHRDLKIENIMISDSSEIKIIDFGLSNIYDSRKQ 299 Query: 1103 DGLLHTSCGTPAYVAPEVINRKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKI 1282 LHT CG+ + APE++ Y G + D+WS GV+LFVL+ G +PF D+N +++KI Sbjct: 300 ---LHTFCGSLYFAAPELLKANPYTGPEVDVWSFGVVLFVLVCGKVPFDDENSSVLHEKI 356 Query: 1283 GKAEFKCPSWFSSDXXXXXXXXXDPNPSTRISIEKIMEHPWFRKGLD 1423 + + + P S + +P R ++++++EH W +G + Sbjct: 357 KQGKVEYPQHLSIEVISLLSKMLVVDPKRRATLKQVVEHHWMVRGFN 403
>P12370:KAPC_DROME cAMP-dependent protein kinase catalytic subunit - Drosophila| melanogaster (Fruit fly) Length = 353 Score = 154 bits (390), Expect = 1e-36 Identities = 84/228 (36%), Positives = 134/228 (58%), Gaps = 1/228 (0%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 +E K LG G+F +V ++ T A+K+ DK+KV+K + E +++ ++ P Sbjct: 46 FERIKTLGTGSFGRVMIVQHKPTKDYYAMKILDKQKVVKLKQVEHTLNEKRILQAIQFPF 105 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNKVQR-GRLKEDAARKYFQQLICAVDFCHSRGV 1000 +V + + +Y VLE+V GGE+F+ +++ GR E +R Y Q++ A ++ H + Sbjct: 106 LVSLRYHFKDNSNLYMVLEYVPGGEMFSHLRKVGRFSEPHSRFYAAQIVLAFEYLHYLDL 165 Query: 1001 YHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKGYDG 1180 +RDLKPENLL+D LKV+DFG + +R+ G T CGTP Y+APE+I KGY+ Sbjct: 166 IYRDLKPENLLIDSQGYLKVTDFGFA-----KRVKGRTWTLCGTPEYLAPEIILSKGYNK 220 Query: 1181 AKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSD 1324 A D W+ GV+++ + AGY PF + +Y+KI + + PS F SD Sbjct: 221 A-VDWWALGVLVYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFGSD 267
>O54863:TSSK2_MOUSE Testis-specific serine/threonine-protein kinase 2 - Mus musculus| (Mouse) Length = 357 Score = 154 bits (389), Expect = 1e-36 Identities = 93/264 (35%), Positives = 146/264 (55%), Gaps = 8/264 (3%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 Y +G LG+G++AKV A + +VA+K+ D++K + + RE+ ++ V H + Sbjct: 12 YIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLPREMDILATVNHRS 71 Query: 824 IVQMYEVMATKT-KIYFVLEHVKGGELFNKVQ-RGRLKEDAARKYFQQLICAVDFCHSRG 997 I++ YE+ T +IY V+E G+L ++ RG L ED K F+Q+ AV +CH Sbjct: 72 IIKTYEIFETSDGRIYIVMELGVQGDLLTFIKCRGALHEDVGGKMFRQVSSAVKYCHDLD 131 Query: 998 VYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDG-----LLHTSCGTPAYVAPEVIN 1162 V HRDLK ENLLLD++ N+K+SDFG S C R DG L T CG+ AY APEV Sbjct: 132 VVHRDLKCENLLLDKDFNIKLSDFGFS--KGCLR-DGSGRIVLSKTFCGSAAYAAPEVRQ 188 Query: 1163 RKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNM-YKKIGKAEFKCPSWFSSDXXXXX 1339 Y DIWS GVIL++++ G +P+ D ++ + +K + +F + + Sbjct: 189 GIPYQPKVYDIWSLGVILYIMVCGSMPYDDSDIKKLRIQKEHRVDFPRSKNLTGECKDLI 248 Query: 1340 XXXXDPNPSTRISIEKIMEHPWFR 1411 P+ + R+ I++I+ H W + Sbjct: 249 YRILQPDVNRRLHIDEILSHSWLQ 272
>O88831:KKCC2_RAT Calcium/calmodulin-dependent protein kinase kinase 2 - Rattus| norvegicus (Rat) Length = 587 Score = 154 bits (389), Expect = 1e-36 Identities = 89/288 (30%), Positives = 152/288 (52%), Gaps = 29/288 (10%) Frame = +2 Query: 629 ILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKG--------------- 763 + +++Y + +G+G++ V A N + A+KV K+K+++ Sbjct: 159 VQLNQYTLKDEIGKGSYGVVKLAYNENDNTYYAMKVLSKKKLIRQAGFPRRPPPRGTRPA 218 Query: 764 --------GLTDQIKREISVMKLVKHPNIVQMYEVM--ATKTKIYFVLEHVKGGELFNKV 913 G +Q+ +EI+++K + HPN+V++ EV+ + +Y V E V G + Sbjct: 219 PGGCIQPRGPIEQVYQEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGPVMEVP 278 Query: 914 QRGRLKEDAARKYFQQLICAVDFCHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISEC 1093 L ED AR YFQ LI +++ H + + HRD+KP NLL+ E+ ++K++DFG+S +E Sbjct: 279 TLKPLSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVS--NEF 336 Query: 1094 RRLDGLLHTSCGTPAYVAPEVIN--RKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMN 1267 + D LL + GTPA++APE ++ RK + G D+W+ GV L+ + G PF D+ +M Sbjct: 337 KGSDALLSNTVGTPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMC 396 Query: 1268 MYKKIGKAEFKCPSW--FSSDXXXXXXXXXDPNPSTRISIEKIMEHPW 1405 ++ KI + P + D D NP +RI + +I HPW Sbjct: 397 LHSKIKSQALEFPDQPDIAEDLKDLITRMLDKNPESRIVVPEIKLHPW 444
>Q8C078:KKCC2_MOUSE Calcium/calmodulin-dependent protein kinase kinase 2 - Mus musculus| (Mouse) Length = 588 Score = 154 bits (389), Expect = 1e-36 Identities = 89/288 (30%), Positives = 152/288 (52%), Gaps = 29/288 (10%) Frame = +2 Query: 629 ILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKG--------------- 763 + +++Y + +G+G++ V A N + A+KV K+K+++ Sbjct: 160 VQLNQYTLKDEIGKGSYGVVKLAYNENDNTYYAMKVLSKKKLIRQAGFPRRPPPRGARPA 219 Query: 764 --------GLTDQIKREISVMKLVKHPNIVQMYEVM--ATKTKIYFVLEHVKGGELFNKV 913 G +Q+ +EI+++K + HPN+V++ EV+ + +Y V E V G + Sbjct: 220 PGGCIQPRGPIEQVYQEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGPVMEVP 279 Query: 914 QRGRLKEDAARKYFQQLICAVDFCHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISEC 1093 L ED AR YFQ LI +++ H + + HRD+KP NLL+ E+ ++K++DFG+S +E Sbjct: 280 TLKPLSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVS--NEF 337 Query: 1094 RRLDGLLHTSCGTPAYVAPEVIN--RKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMN 1267 + D LL + GTPA++APE ++ RK + G D+W+ GV L+ + G PF D+ +M Sbjct: 338 KGSDALLSNTVGTPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMC 397 Query: 1268 MYKKIGKAEFKCPSW--FSSDXXXXXXXXXDPNPSTRISIEKIMEHPW 1405 ++ KI + P + D D NP +RI + +I HPW Sbjct: 398 LHSKIKSQALEFPDQPDIAEDLKDLITRMLDKNPESRIVVPEIKLHPW 445
>P11275:KCC2A_RAT Calcium/calmodulin-dependent protein kinase type II alpha chain -| Rattus norvegicus (Rat) Length = 478 Score = 154 bits (389), Expect = 1e-36 Identities = 92/263 (34%), Positives = 146/263 (55%), Gaps = 8/263 (3%) Frame = +2 Query: 641 KYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHP 820 +Y++ + LG+G F+ V + Q A K+ + +K L +++RE + +L+KHP Sbjct: 12 EYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKK-LSARDHQKLEREARICRLLKHP 70 Query: 821 NIVQMYEVMATKTKIYFVLEHVKGGELFNK-VQRGRLKEDAARKYFQQLICAVDFCHSRG 997 NIV++++ ++ + Y + + V GGELF V R E A QQ++ AV CH G Sbjct: 71 NIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMG 130 Query: 998 VYHRDLKPENLLLD---ENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRK 1168 V HRDLKPENLLL + + +K++DFGL+ E GTP Y++PEV+ + Sbjct: 131 VVHRDLKPENLLLASKLKGAAVKLADFGLAI--EVEGEQQAWFGFAGTPGYLSPEVLRKD 188 Query: 1169 GYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKI--GKAEFKCPSW--FSSDXXXX 1336 Y G D+W+CGVIL++L+ GY PF D++ +Y++I G +F P W + + Sbjct: 189 PY-GKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDL 247 Query: 1337 XXXXXDPNPSTRISIEKIMEHPW 1405 NPS RI+ + ++HPW Sbjct: 248 INKMLTINPSKRITAAEALKHPW 270
>Q5RCC4:KCC2A_PONPY Calcium/calmodulin-dependent protein kinase type II alpha chain -| Pongo pygmaeus (Orangutan) Length = 478 Score = 154 bits (389), Expect = 1e-36 Identities = 92/263 (34%), Positives = 146/263 (55%), Gaps = 8/263 (3%) Frame = +2 Query: 641 KYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHP 820 +Y++ + LG+G F+ V + Q A K+ + +K L +++RE + +L+KHP Sbjct: 12 EYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKK-LSARDHQKLEREARICRLLKHP 70 Query: 821 NIVQMYEVMATKTKIYFVLEHVKGGELFNK-VQRGRLKEDAARKYFQQLICAVDFCHSRG 997 NIV++++ ++ + Y + + V GGELF V R E A QQ++ AV CH G Sbjct: 71 NIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMG 130 Query: 998 VYHRDLKPENLLLD---ENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRK 1168 V HRDLKPENLLL + + +K++DFGL+ E GTP Y++PEV+ + Sbjct: 131 VVHRDLKPENLLLASKLKGAAVKLADFGLAI--EVEGEQQAWFGFAGTPGYLSPEVLRKD 188 Query: 1169 GYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKI--GKAEFKCPSW--FSSDXXXX 1336 Y G D+W+CGVIL++L+ GY PF D++ +Y++I G +F P W + + Sbjct: 189 PY-GKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDL 247 Query: 1337 XXXXXDPNPSTRISIEKIMEHPW 1405 NPS RI+ + ++HPW Sbjct: 248 INKMLTINPSKRITAAEALKHPW 270
>P11798:KCC2A_MOUSE Calcium/calmodulin-dependent protein kinase type II alpha chain - Mus| musculus (Mouse) Length = 478 Score = 154 bits (389), Expect = 1e-36 Identities = 92/263 (34%), Positives = 146/263 (55%), Gaps = 8/263 (3%) Frame = +2 Query: 641 KYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHP 820 +Y++ + LG+G F+ V + Q A K+ + +K L +++RE + +L+KHP Sbjct: 12 EYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKK-LSARDHQKLEREARICRLLKHP 70 Query: 821 NIVQMYEVMATKTKIYFVLEHVKGGELFNK-VQRGRLKEDAARKYFQQLICAVDFCHSRG 997 NIV++++ ++ + Y + + V GGELF V R E A QQ++ AV CH G Sbjct: 71 NIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMG 130 Query: 998 VYHRDLKPENLLLD---ENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRK 1168 V HRDLKPENLLL + + +K++DFGL+ E GTP Y++PEV+ + Sbjct: 131 VVHRDLKPENLLLASKLKGAAVKLADFGLAI--EVEGEQQAWFGFAGTPGYLSPEVLRKD 188 Query: 1169 GYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKI--GKAEFKCPSW--FSSDXXXX 1336 Y G D+W+CGVIL++L+ GY PF D++ +Y++I G +F P W + + Sbjct: 189 PY-GKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDL 247 Query: 1337 XXXXXDPNPSTRISIEKIMEHPW 1405 NPS RI+ + ++HPW Sbjct: 248 INKMLTINPSKRITAAEALKHPW 270
>Q9UQM7:KCC2A_HUMAN Calcium/calmodulin-dependent protein kinase type II alpha chain -| Homo sapiens (Human) Length = 478 Score = 154 bits (389), Expect = 1e-36 Identities = 92/263 (34%), Positives = 146/263 (55%), Gaps = 8/263 (3%) Frame = +2 Query: 641 KYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHP 820 +Y++ + LG+G F+ V + Q A K+ + +K L +++RE + +L+KHP Sbjct: 12 EYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKK-LSARDHQKLEREARICRLLKHP 70 Query: 821 NIVQMYEVMATKTKIYFVLEHVKGGELFNK-VQRGRLKEDAARKYFQQLICAVDFCHSRG 997 NIV++++ ++ + Y + + V GGELF V R E A QQ++ AV CH G Sbjct: 71 NIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMG 130 Query: 998 VYHRDLKPENLLLD---ENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRK 1168 V HRDLKPENLLL + + +K++DFGL+ E GTP Y++PEV+ + Sbjct: 131 VVHRDLKPENLLLASKLKGAAVKLADFGLAI--EVEGEQQAWFGFAGTPGYLSPEVLRKD 188 Query: 1169 GYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKI--GKAEFKCPSW--FSSDXXXX 1336 Y G D+W+CGVIL++L+ GY PF D++ +Y++I G +F P W + + Sbjct: 189 PY-GKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDL 247 Query: 1337 XXXXXDPNPSTRISIEKIMEHPW 1405 NPS RI+ + ++HPW Sbjct: 248 INKMLTINPSKRITAAEALKHPW 270
>P27466:KCC1_YEAST Calcium/calmodulin-dependent protein kinase I - Saccharomyces| cerevisiae (Baker's yeast) Length = 446 Score = 154 bits (388), Expect = 2e-36 Identities = 93/267 (34%), Positives = 147/267 (55%), Gaps = 12/267 (4%) Frame = +2 Query: 641 KYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLT--DQIKREISVMKLVK 814 KY GK LG GTF V A+N ET + VA+K+ K K LKG + + E+ +++ + Sbjct: 36 KYVFGKTLGAGTFGVVRQAKNTETGEDVAVKILIK-KALKGNKVQLEALYDELDILQRLH 94 Query: 815 HPNIVQMYEVMATKTKIYFVLEHVKGGELFNKV-QRGRLKEDAARKYFQQLICAVDFCHS 991 HPNIV + +K K Y + + KGGELF+++ ++G+ E+ A + +++ AV + HS Sbjct: 95 HPNIVAFKDWFESKDKFYIITQLAKGGELFDRILKKGKFTEEDAVRILVEILSAVKYMHS 154 Query: 992 RGVYHRDLKPENLLL---DENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVIN 1162 + + HRDLKPENLL + S L V+DFG++ + + LL+ G+ YVAPEV+ Sbjct: 155 QNIVHRDLKPENLLYIDKSDESPLVVADFGIA--KRLKSDEELLYKPAGSLGYVAPEVLT 212 Query: 1163 RKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAE----FKCPSW--FSSD 1324 + G+ G DIWS GVI + L+ GY F+ + + + + E F P W S+ Sbjct: 213 QDGH-GKPCDIWSIGVITYTLLCGYSAFRAERVQDFLDECTTGEYPVKFHRPYWDSVSNK 271 Query: 1325 XXXXXXXXXDPNPSTRISIEKIMEHPW 1405 + +PS R + +++E PW Sbjct: 272 AKQFILKALNLDPSKRPTAAELLEDPW 298
>P10666:KS6AB_XENLA Ribosomal protein S6 kinase 2 beta - Xenopus laevis (African clawed| frog) Length = 629 Score = 153 bits (387), Expect = 2e-36 Identities = 91/260 (35%), Positives = 148/260 (56%), Gaps = 9/260 (3%) Frame = +2 Query: 656 KMLGQGTFAKVYHARNI---ETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPNI 826 K+LGQG+F KV+ R I + +Q A+KV K+ LK + K E ++ V HP + Sbjct: 66 KVLGQGSFGKVFLVRKITPPDANQLYAMKVL-KKATLKVRDRVRTKMERDILADVHHPFV 124 Query: 827 VQMYEVMATKTKIYFVLEHVKGGELFNKVQRGRL-KEDAARKYFQQLICAVDFCHSRGVY 1003 V+++ T+ K+Y +L+ ++GG+LF ++ + + E+ + Y +L +D HS G+ Sbjct: 125 VRLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHSLGII 184 Query: 1004 HRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKGYDGA 1183 +RDLKPEN+LLDE ++K++DFGLS E + ++ CGT Y+APEV+NR+G+ Sbjct: 185 YRDLKPENILLDEEGHIKLTDFGLS--KEAIDHEKKAYSFCGTVEYMAPEVVNRQGHSHG 242 Query: 1184 KADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXXXDPNP 1363 AD WS GV++F ++ G LPFQ K+ I KA+ P + S++ N Sbjct: 243 -ADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSNEAQSLLRALFKRNA 301 Query: 1364 STRI-----SIEKIMEHPWF 1408 + R+ E++ HP+F Sbjct: 302 TNRLGSGVEGAEELKRHPFF 321 Score = 123 bits (309), Expect = 3e-27 Identities = 75/226 (33%), Positives = 119/226 (52%), Gaps = 6/226 (2%) Frame = +2 Query: 587 PACLPAIMGEQKGNILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGG 766 P L K + Y + + +G G+++ + T+ A+KV DK K Sbjct: 397 PPVLSVPKTHSKNVLFTDVYTVRETIGVGSYSVCKRCVHKGTNMEYAVKVIDKSK----- 451 Query: 767 LTDQIKREISVMKLV-KHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQRGRLKEDAA 943 EI +++ +HPNI+ + +V IY V E ++GGEL +++ R + + Sbjct: 452 --RDPSEEIEILRRYGQHPNIITLKDVYEECNSIYLVTELMRGGELLDRILRQKFFSERE 509 Query: 944 RKYFQQLIC-AVDFCHSRGVYHRDLKPENLLLDENS----NLKVSDFGLSTISECRRLDG 1108 +C V++ HS+GV HRDLKP N+L + S ++++ DFG S + R +G Sbjct: 510 ACSVLFTVCKTVEYLHSQGVVHRDLKPSNILYVDESGDPESIRICDFGFS--KQLRAENG 567 Query: 1109 LLHTSCGTPAYVAPEVINRKGYDGAKADIWSCGVILFVLMAGYLPF 1246 LL T C T +VAPEV+ R+GYD DIWS G++L+ ++AGY PF Sbjct: 568 LLMTPCYTANFVAPEVLKRQGYDEG-CDIWSLGILLYTMLAGYTPF 612
>Q15418:KS6A1_HUMAN Ribosomal protein S6 kinase alpha-1 - Homo sapiens (Human)| Length = 735 Score = 153 bits (387), Expect = 2e-36 Identities = 91/264 (34%), Positives = 150/264 (56%), Gaps = 9/264 (3%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQS---VAIKVTDKEKVLKGGLTDQIKREISVMKLVK 814 +E+ K+LGQG+F KV+ R + S A+KV K+ LK + K E ++ V Sbjct: 62 FELLKVLGQGSFGKVFLVRKVTRPDSGHLYAMKVL-KKATLKVRDRVRTKMERDILADVN 120 Query: 815 HPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQRGRL-KEDAARKYFQQLICAVDFCHS 991 HP +V+++ T+ K+Y +L+ ++GG+LF ++ + + E+ + Y +L +D HS Sbjct: 121 HPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHS 180 Query: 992 RGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKG 1171 G+ +RDLKPEN+LLDE ++K++DFGLS E + ++ CGT Y+APEV+NR+G Sbjct: 181 LGIIYRDLKPENILLDEEGHIKLTDFGLS--KEAIDHEKKAYSFCGTVEYMAPEVVNRQG 238 Query: 1172 YDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXXX 1351 + + AD WS GV++F ++ G LPFQ K+ I KA+ P + S++ Sbjct: 239 HSHS-ADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSTEAQSLLRALF 297 Query: 1352 DPNPSTRI-----SIEKIMEHPWF 1408 NP+ R+ E+I H ++ Sbjct: 298 KRNPANRLGSGPDGAEEIKRHVFY 321 Score = 133 bits (335), Expect = 3e-30 Identities = 84/274 (30%), Positives = 143/274 (52%), Gaps = 12/274 (4%) Frame = +2 Query: 620 KGNILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISV 799 K + Y + + +G G++++ + T+ A+KV DK K D + + Sbjct: 410 KNLVFSDGYVVKETIGVGSYSECKRCVHKATNMEYAVKVIDKSK------RDPSEEIEIL 463 Query: 800 MKLVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQRGRLKEDAARKYFQQLIC-AV 976 ++ +HPNI+ + +V +Y V E ++GGEL +K+ R + + + I V Sbjct: 464 LRYGQHPNIITLKDVYDDGKHVYLVTELMRGGELLDKILRQKFFSEREASFVLHTIGKTV 523 Query: 977 DFCHSRGVYHRDLKPENLL-LDENSN---LKVSDFGLSTISECRRLDGLLHTSCGTPAYV 1144 ++ HS+GV HRDLKP N+L +DE+ N L++ DFG + + R +GLL T C T +V Sbjct: 524 EYLHSQGVVHRDLKPSNILYVDESGNPECLRICDFGFA--KQLRAENGLLMTPCYTANFV 581 Query: 1145 APEVINRKGYDGAKADIWSCGVILFVLMAGYLPFQD---KNLMNMYKKIGKAEFKCP--S 1309 APEV+ R+GYD DIWS G++L+ ++AGY PF + + +IG +F + Sbjct: 582 APEVLKRQGYDEG-CDIWSLGILLYTMLAGYTPFANGPSDTPEEILTRIGSGKFTLSGGN 640 Query: 1310 W--FSSDXXXXXXXXXDPNPSTRISIEKIMEHPW 1405 W S +P R++ +++++HPW Sbjct: 641 WNTVSETAKDLVSKMLHVDPHQRLTAKQVLQHPW 674
>Q9DG02:KCC2D_XENLA Calcium/calmodulin-dependent protein kinase type II delta chain -| Xenopus laevis (African clawed frog) Length = 475 Score = 153 bits (387), Expect = 2e-36 Identities = 91/263 (34%), Positives = 147/263 (55%), Gaps = 8/263 (3%) Frame = +2 Query: 641 KYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHP 820 +Y++ + LG+G F+ V I Q A K+ + +K L +++RE + +L+KHP Sbjct: 12 EYQLFEELGKGAFSVVRRCIKINIGQEYAAKIINTKK-LSARDHQKLEREAKICRLLKHP 70 Query: 821 NIVQMYEVMATKTKIYFVLEHVKGGELFNK-VQRGRLKEDAARKYFQQLICAVDFCHSRG 997 NIV++++ ++ + Y V + V GGELF V R E A QQ++ +V+ CH G Sbjct: 71 NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNG 130 Query: 998 VYHRDLKPENLLLD---ENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRK 1168 + HRDLKPENLLL + + +K++DFGL+ E + GTP Y++PEV+ + Sbjct: 131 IVHRDLKPENLLLASKLKGAAVKLADFGLAI--EVQGDQQAWFGFAGTPGYLSPEVLRKD 188 Query: 1169 GYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKI--GKAEFKCPSW--FSSDXXXX 1336 Y G D+W+CGVIL++L+ GY PF D++ +Y++I G +F P W + + Sbjct: 189 PY-GKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDL 247 Query: 1337 XXXXXDPNPSTRISIEKIMEHPW 1405 NP+ RI+ + + HPW Sbjct: 248 INKMLTINPAKRINATEALRHPW 270
>P52304:POLO_DROME Serine/threonine-protein kinase polo - Drosophila melanogaster (Fruit| fly) Length = 576 Score = 153 bits (386), Expect = 3e-36 Identities = 83/257 (32%), Positives = 136/257 (52%), Gaps = 1/257 (0%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 Y+ + G+G FAK Y ++ET A K+ K+ ++K ++ +EI++ + + HPN Sbjct: 25 YKRMRFFGKGGFAKCYEIIDVETDDVFAGKIVSKKLMIKHNQKEKTAQEITIHRSLNHPN 84 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNKVQRGR-LKEDAARKYFQQLICAVDFCHSRGV 1000 IV+ + IY VLE K + +R + + E R Y Q+I V + H + Sbjct: 85 IVKFHNYFEDSQNIYIVLELCKKRSMMELHKRRKSITEFECRYYIYQIIQGVKYLHDNRI 144 Query: 1001 YHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKGYDG 1180 HRDLK NL L++ ++K+ DFGL+T E T CGTP Y+APE++ +KG+ Sbjct: 145 IHRDLKLGNLFLNDLLHVKIGDFGLATRIEYE--GERKKTLCGTPNYIAPEILTKKGHS- 201 Query: 1181 AKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXXXDPN 1360 + DIWS G +++ L+ G PF+ K L + Y KI K E++ PS+ PN Sbjct: 202 FEVDIWSIGCVMYTLLVGQPPFETKTLKDTYSKIKKCEYRVPSYLRKPAADMVIAMLQPN 261 Query: 1361 PSTRISIEKIMEHPWFR 1411 P +R +I +++ + + Sbjct: 262 PESRPAIGQLLNFEFLK 278
>Q64617:KPCL_RAT Protein kinase C eta type - Rattus norvegicus (Rat)| Length = 683 Score = 153 bits (386), Expect = 3e-36 Identities = 85/265 (32%), Positives = 147/265 (55%), Gaps = 8/265 (3%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVK-HP 820 +E ++LG+G+F KV AR ET + A+KV K+ +L+ + E ++ L + HP Sbjct: 355 FEFIRVLGKGSFGKVMLARIKETGELYAVKVLKKDVILQDDDVECTMTEKRILSLARNHP 414 Query: 821 NIVQMYEVMATKTKIYFVLEHVKGGELFNKVQRGRLKEDA-ARKYFQQLICAVDFCHSRG 997 + Q++ T +++FV+E V GG+L +Q+ R ++A AR Y ++I A+ F H +G Sbjct: 415 FLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISALMFLHEKG 474 Query: 998 VYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKGYD 1177 + +RDLK +N+LLD + K++DFG+ C + T CGTP Y+APE++ Y Sbjct: 475 IIYRDLKLDNVLLDHEGHCKLADFGMCKEGICNGV--TTATFCGTPDYIAPEILQEMLY- 531 Query: 1178 GAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXXXDP 1357 G D W+ GV+L+ ++ G+ PF+ +N ++++ I E P+W D Sbjct: 532 GPAVDWWAMGVLLYEMLCGHAPFEAENEDDLFEAILNDEVVYPTWLHEDATGILKSFMTK 591 Query: 1358 NPSTRISI------EKIMEHPWFRK 1414 NP+ R+ +I+ HP+F++ Sbjct: 592 NPTMRLGSLTQGGEHEILRHPFFKE 616
>P23298:KPCL_MOUSE Protein kinase C eta type - Mus musculus (Mouse)| Length = 683 Score = 153 bits (386), Expect = 3e-36 Identities = 85/265 (32%), Positives = 147/265 (55%), Gaps = 8/265 (3%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVK-HP 820 +E ++LG+G+F KV AR ET + A+KV K+ +L+ + E ++ L + HP Sbjct: 355 FEFIRVLGKGSFGKVMLARIKETGELYAVKVLKKDVILQDDDVECTMTEKRILSLARNHP 414 Query: 821 NIVQMYEVMATKTKIYFVLEHVKGGELFNKVQRGRLKEDA-ARKYFQQLICAVDFCHSRG 997 + Q++ T +++FV+E V GG+L +Q+ R ++A AR Y ++I A+ F H +G Sbjct: 415 FLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISALMFLHEKG 474 Query: 998 VYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKGYD 1177 + +RDLK +N+LLD + K++DFG+ C + T CGTP Y+APE++ Y Sbjct: 475 IIYRDLKLDNVLLDHEGHCKLADFGMCKEGICNGV--TTATFCGTPDYIAPEILQEMLY- 531 Query: 1178 GAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXXXDP 1357 G D W+ GV+L+ ++ G+ PF+ +N ++++ I E P+W D Sbjct: 532 GPAVDWWAMGVLLYEMLCGHAPFEAENEDDLFEAILNDEVVYPTWLHEDARGILKSFMTK 591 Query: 1358 NPSTRISI------EKIMEHPWFRK 1414 NP+ R+ +I+ HP+F++ Sbjct: 592 NPTMRLGSLTQGGEHEILRHPFFKE 616
>Q6DGS3:KCC2D_DANRE Calcium/calmodulin-dependent protein kinase type II delta chain -| Danio rerio (Zebrafish) (Brachydanio rerio) Length = 493 Score = 153 bits (386), Expect = 3e-36 Identities = 92/263 (34%), Positives = 147/263 (55%), Gaps = 8/263 (3%) Frame = +2 Query: 641 KYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHP 820 +Y++ + LG+G F+ V I + Q A K+ + +K L +++RE + +L+KHP Sbjct: 12 EYQLFEELGKGAFSVVRRCVKISSGQEYAAKIINTKK-LSARDHQKLEREARICRLLKHP 70 Query: 821 NIVQMYEVMATKTKIYFVLEHVKGGELFNK-VQRGRLKEDAARKYFQQLICAVDFCHSRG 997 NIV++++ ++ + Y V + V GGELF V R E A QQ++ +V CH G Sbjct: 71 NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVHHCHVNG 130 Query: 998 VYHRDLKPENLLLD---ENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRK 1168 + HRDLKPENLLL + + +K++DFGL+ E + GTP Y++PEV+ + Sbjct: 131 IVHRDLKPENLLLASKMKGAAVKLADFGLAI--EVQGDQQAWFGFAGTPGYLSPEVLRKD 188 Query: 1169 GYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKI--GKAEFKCPSW--FSSDXXXX 1336 Y G D+W+CGVIL++L+ GY PF D++ +Y++I G +F P W + + Sbjct: 189 PY-GKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDL 247 Query: 1337 XXXXXDPNPSTRISIEKIMEHPW 1405 NPS RI+ + +HPW Sbjct: 248 INKMLTINPSKRITAAEAPKHPW 270
>Q9Z2A0:PDPK1_MOUSE 3-phosphoinositide-dependent protein kinase 1 - Mus musculus (Mouse)| Length = 559 Score = 152 bits (385), Expect = 4e-36 Identities = 79/240 (32%), Positives = 135/240 (56%), Gaps = 1/240 (0%) Frame = +2 Query: 599 PAIMGEQKGNILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQ 778 PA + Q ++ GK+LG+G+F+ V AR + TS+ AIK+ +K ++K Sbjct: 70 PAQLPPQPRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPY 129 Query: 779 IKREISVMKLVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQR-GRLKEDAARKYF 955 + RE VM + HP V++Y K+YF L + K GEL +++ G E R Y Sbjct: 130 VTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYT 189 Query: 956 QQLICAVDFCHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTP 1135 +++ A+++ H +G+ HRDLKPEN+LL+E+ +++++DFG + + ++ GT Sbjct: 190 AEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTA 249 Query: 1136 AYVAPEVINRKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWF 1315 YV+PE++ K +D+W+ G I++ L+AG PF+ N +++KI K E+ P F Sbjct: 250 QYVSPELLTEKS-ACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYHFPEKF 308
>P22517:KCC2_YEAST Calcium/calmodulin-dependent protein kinase II - Saccharomyces| cerevisiae (Baker's yeast) Length = 447 Score = 152 bits (385), Expect = 4e-36 Identities = 93/279 (33%), Positives = 152/279 (54%), Gaps = 12/279 (4%) Frame = +2 Query: 605 IMGEQKGNILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTD--Q 778 + G+ + + Y G+ LG G+F V AR + T++ VAIK+ K K L+G Sbjct: 34 LSGQPESYVNRTNYIFGRTLGAGSFGVVRQARKLSTNEDVAIKILLK-KALQGNNVQLQM 92 Query: 779 IKREISVMKLVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKV-QRGRLKEDAARKYF 955 + E+S+++ + HPNIV + +K K Y V + GGELF+++ RG+ E A + Sbjct: 93 LYEELSILQKLSHPNIVSFKDWFESKDKFYIVTQLATGGELFDRILSRGKFTEVDAVEII 152 Query: 956 QQLICAVDFCHSRGVYHRDLKPENLLL---DENSNLKVSDFGLSTISECRRLDGLLHTSC 1126 Q++ AV++ HS+ V HRDLKPEN+L ENS L ++DFG++ + + + L++ + Sbjct: 153 VQILGAVEYMHSKNVVHRDLKPENVLYVDKSENSPLVIADFGIA--KQLKGEEDLIYKAA 210 Query: 1127 GTPAYVAPEVINRKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAE---- 1294 G+ YVAPEV+ + G+ G DIWS GVI + L+ GY PF +++ ++ + Sbjct: 211 GSLGYVAPEVLTQDGH-GKPCDIWSIGVITYTLLCGYSPFIAESVEGFMEECTASRYPVT 269 Query: 1295 FKCPSW--FSSDXXXXXXXXXDPNPSTRISIEKIMEHPW 1405 F P W S D NP+ R + ++++ PW Sbjct: 270 FHMPYWDNISIDVKRFILKALRLNPADRPTATELLDDPW 308
>P53682:CDPK1_ORYSJ Calcium-dependent protein kinase, isoform 1 - Oryza sativa subsp.| japonica (Rice) Length = 534 Score = 152 bits (385), Expect = 4e-36 Identities = 95/276 (34%), Positives = 143/276 (51%), Gaps = 9/276 (3%) Frame = +2 Query: 605 IMGEQKGNILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIK 784 ++G + N+ Y +G+ LGQG F K Y I T A K K + + ++ Sbjct: 61 VLGYKTPNV-RELYTLGRELGQGQFGKTYLCTEISTGCQYACKTILKSNLRCVSDIEDVR 119 Query: 785 REISVMK-LVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQ-RGRLKEDAARKYFQ 958 REI +M L NIV + + + ++ V+E GGELF+K+Q RG E A + + Sbjct: 120 REIQIMHHLSGQKNIVTIKDTYEDEQAVHIVMELCAGGELFSKIQKRGHYSERKAAELIK 179 Query: 959 QLICAVDFCHSRGVYHRDLKPENLLL---DENSNLKVSDFGLSTISECRRLDGLLHTSCG 1129 ++ ++ CHS GV HRDLKPEN LL D+ ++K DFGLS R + G Sbjct: 180 IIVGIIETCHSHGVMHRDLKPENFLLLDADDEFSVKAIDFGLSVFF---RPGQVFREVVG 236 Query: 1130 TPAYVAPEVINRKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKI--GKAEFKC 1303 +P Y+APEV+ ++ G +ADIW+ GVIL+VL+ G PF +Y+K+ G+ +FK Sbjct: 237 SPYYIAPEVLEKR--YGPEADIWTAGVILYVLLTGVPPFWADTQSGIYEKVLDGRIDFKS 294 Query: 1304 PSW--FSSDXXXXXXXXXDPNPSTRISIEKIMEHPW 1405 W S P PS R+ ++++HPW Sbjct: 295 NRWPRISDSAKDLIKKMLCPYPSERLKAHEVLKHPW 330
>O15530:PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 - Homo sapiens (Human)| Length = 556 Score = 152 bits (384), Expect = 6e-36 Identities = 76/225 (33%), Positives = 131/225 (58%), Gaps = 1/225 (0%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVKHPN 823 ++ GK+LG+G+F+ V AR + TS+ AIK+ +K ++K + RE VM + HP Sbjct: 82 FKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPF 141 Query: 824 IVQMYEVMATKTKIYFVLEHVKGGELFNKVQR-GRLKEDAARKYFQQLICAVDFCHSRGV 1000 V++Y K+YF L + K GEL +++ G E R Y +++ A+++ H +G+ Sbjct: 142 FVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGI 201 Query: 1001 YHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKGYDG 1180 HRDLKPEN+LL+E+ +++++DFG + + ++ GT YV+PE++ K Sbjct: 202 IHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEKS-AC 260 Query: 1181 AKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWF 1315 +D+W+ G I++ L+AG PF+ N +++KI K E+ P F Sbjct: 261 KSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKF 305
>Q63531:KS6A1_RAT Ribosomal protein S6 kinase alpha-1 - Rattus norvegicus (Rat)| Length = 735 Score = 152 bits (384), Expect = 6e-36 Identities = 90/264 (34%), Positives = 150/264 (56%), Gaps = 9/264 (3%) Frame = +2 Query: 644 YEMGKMLGQGTFAKVYHARNI---ETSQSVAIKVTDKEKVLKGGLTDQIKREISVMKLVK 814 +E+ K+LGQG+F KV+ R + + A+KV K+ LK + K E ++ V Sbjct: 62 FELLKVLGQGSFGKVFLVRKVTRPDNGHLYAMKVL-KKATLKVRDRVRTKMERDILADVN 120 Query: 815 HPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQRGRL-KEDAARKYFQQLICAVDFCHS 991 HP +V+++ T+ K+Y +L+ ++GG+LF ++ + + E+ + Y +L +D HS Sbjct: 121 HPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHS 180 Query: 992 RGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVINRKG 1171 G+ +RDLKPEN+LLDE ++K++DFGLS E + ++ CGT Y+APEV+NR+G Sbjct: 181 LGIIYRDLKPENILLDEEGHIKLTDFGLS--KEAIDHEKKAYSFCGTVEYMAPEVVNRQG 238 Query: 1172 YDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXXXXX 1351 + + AD WS GV++F ++ G LPFQ K+ I KA+ P + S++ Sbjct: 239 HTHS-ADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSTEAQSLLRALF 297 Query: 1352 DPNPSTRI-----SIEKIMEHPWF 1408 NP+ R+ E+I H ++ Sbjct: 298 KRNPANRLGSGPDGAEEIKRHIFY 321 Score = 131 bits (330), Expect = 1e-29 Identities = 84/275 (30%), Positives = 141/275 (51%), Gaps = 13/275 (4%) Frame = +2 Query: 620 KGNILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISV 799 K + Y + + +G G+++ + T+ A+KV DK K D + + Sbjct: 410 KNLVFSDGYIVKETIGVGSYSVCKRCVHKATNMEYAVKVIDKSK------RDPSEEIEIL 463 Query: 800 MKLVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQRGRLKEDAARKYFQQLIC-AV 976 ++ +HPNI+ + +V +Y V E ++GGEL +K+ R + + + I V Sbjct: 464 LRYGQHPNIITLKDVYDDSKHVYLVTELMRGGELLDKILRQKFFSEREASFVLYTISKTV 523 Query: 977 DFCHSRGVYHRDLKPENLL-LDENSN---LKVSDFGLSTISECRRLDGLLHTSCGTPAYV 1144 ++ HS+GV HRDLKP N+L +DE+ N L++ DFG + + R +GLL T C T +V Sbjct: 524 EYLHSQGVVHRDLKPSNILYVDESGNPECLRICDFGFA--KQLRAENGLLMTPCYTANFV 581 Query: 1145 APEVINRKGYDGAKADIWSCGVILFVLMAGYLPFQD------KNLMNMYKKIGKAEFKCP 1306 APEV+ R+GYD DIWS GV+L+ ++AGY PF + + ++ GK Sbjct: 582 APEVLKRQGYDEG-CDIWSLGVLLYTMLAGYTPFANGPSDTPEEILTRISS-GKFTLSGG 639 Query: 1307 SW--FSSDXXXXXXXXXDPNPSTRISIEKIMEHPW 1405 +W S +P R++ +++++HPW Sbjct: 640 NWNTVSETAKDLVSKMLHVDPHQRLTAKQVLQHPW 674
>O55173:PDPK1_RAT 3-phosphoinositide-dependent protein kinase 1 - Rattus norvegicus| (Rat) Length = 559 Score = 152 bits (383), Expect = 7e-36 Identities = 79/240 (32%), Positives = 135/240 (56%), Gaps = 1/240 (0%) Frame = +2 Query: 599 PAIMGEQKGNILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQ 778 PA + Q ++ GK+LG+G+F+ V AR + TS+ AIK+ +K ++K Sbjct: 70 PAQLPPQPRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPY 129 Query: 779 IKREISVMKLVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQR-GRLKEDAARKYF 955 + RE VM + HP V++Y K+YF L + K GEL +++ G E R Y Sbjct: 130 VTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYT 189 Query: 956 QQLICAVDFCHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTP 1135 +++ A+++ H +G+ HRDLKPEN+LL+E+ +++++DFG + + ++ GT Sbjct: 190 AEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPDSKQARANSFVGTA 249 Query: 1136 AYVAPEVINRKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWF 1315 YV+PE++ K +D+W+ G I++ L+AG PF+ N +++KI K E+ P F Sbjct: 250 QYVSPELLTEKS-ACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKF 308
>Q9UBS0:KS6B2_HUMAN Ribosomal protein S6 kinase beta-2 - Homo sapiens (Human)| Length = 482 Score = 151 bits (382), Expect = 9e-36 Identities = 88/268 (32%), Positives = 145/268 (54%), Gaps = 10/268 (3%) Frame = +2 Query: 638 HKYEMGKMLGQGTFAKVYHARNIETS---QSVAIKVTDKEKVLKGGL-TDQIKREISVMK 805 H +E+ ++LG+G + KV+ R ++ + + A+KV K K+++ T + E ++++ Sbjct: 65 HCFELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILE 124 Query: 806 LVKHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQR-GRLKEDAARKYFQQLICAVDF 982 VKHP IV++ T K+Y +LE + GGELF ++R G ED A Y ++ A+ Sbjct: 125 SVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLALGH 184 Query: 983 CHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEVIN 1162 HS+G+ +RDLKPEN++L ++K++DFGL E + HT CGT Y+APE++ Sbjct: 185 LHSQGIIYRDLKPENIMLSSQGHIKLTDFGL--CKESIHEGAVTHTFCGTIEYMAPEILV 242 Query: 1163 RKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXXXX 1342 R G++ A D WS G +++ ++ G PF +N KI + + P + + D Sbjct: 243 RSGHNRA-VDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYLTPDARDLVK 301 Query: 1343 XXXDPNPSTRI-----SIEKIMEHPWFR 1411 NPS RI + HP+FR Sbjct: 302 KFLKRNPSQRIGGGPGDAADVQRHPFFR 329
>P34885:KPC1B_CAEEL Protein kinase C-like 1B - Caenorhabditis elegans| Length = 707 Score = 151 bits (382), Expect = 9e-36 Identities = 86/273 (31%), Positives = 142/273 (52%), Gaps = 9/273 (3%) Frame = +2 Query: 623 GNILMHKYEMGKMLGQGTFAKVYHARNIETSQSVAIKVTDKEKVLKGGLTDQIKREISVM 802 G + +H + K+LG+G+F KV A T + AIK+ K+ +++ + E ++ Sbjct: 371 GTLSIHDFTFMKVLGKGSFGKVMLAERKGTDEVYAIKILKKDVIVQDDDVECTMCEKRIL 430 Query: 803 KLV-KHPNIVQMYEVMATKTKIYFVLEHVKGGELFNKVQRGR-LKEDAARKYFQQLICAV 976 L KHP + ++ T +++FV+E+V GG+L ++QR R E AR Y ++ CA+ Sbjct: 431 SLAAKHPFLTALHSSFQTSDRLFFVMEYVNGGDLMFQIQRARKFDESRARFYAAEVTCAL 490 Query: 977 DFCHSRGVYHRDLKPENLLLDENSNLKVSDFGLSTISECRRLDGLLHTSCGTPAYVAPEV 1156 F H V +RDLK +N+LLD + +++DFG+ E D L T CGTP Y+APE+ Sbjct: 491 QFLHRNDVIYRDLKLDNILLDAEGHCRLADFGM--CKEGINKDNLTSTFCGTPDYIAPEI 548 Query: 1157 INRKGYDGAKADIWSCGVILFVLMAGYLPFQDKNLMNMYKKIGKAEFKCPSWFSSDXXXX 1336 + Y G D W+ GV+++ +MAG PF+ N ++++ I + P W S + Sbjct: 549 LQEMEY-GVSVDWWALGVLMYEMMAGQPPFEADNEDDLFEAILNDDVLYPVWLSKEAVNI 607 Query: 1337 XXXXXDPNPSTRISI-------EKIMEHPWFRK 1414 N R+ + I HP+FR+ Sbjct: 608 LKAFMTKNAGKRLGCVVSQGGEDAIRAHPFFRE 640 Database: uniprot_sprot.fasta.out Posted date: Jul 19, 2007 5:58 PM Number of letters in database: 100,686,439 Number of sequences in database: 274,295 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 274295 Number of Hits to DB: 364,653,994 Number of extensions: 8004733 Number of successful extensions: 31300 Number of sequences better than 10.0: 2607 Number of HSP's gapped: 26033 Number of HSP's successfully gapped: 2755 Length of query: 726 Length of database: 100,686,439 Length adjustment: 121 Effective length of query: 605 Effective length of database: 67,496,744 Effective search space: 40835530120 Effective search space used: 40835530120 Neighboring words threshold: 12 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
