ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | FLbaf149g19 |
|---|---|
| Clone Library Name | barley_pub |
>Q05047:C72A1_CATRO Cytochrome P450 72A1 - Catharanthus roseus (Rosy periwinkle)| (Madagascar periwinkle) Length = 524 Score = 230 bits (587), Expect = 1e-59 Identities = 150/506 (29%), Positives = 238/506 (47%), Gaps = 24/506 (4%) Frame = +2 Query: 170 WVVPQRLLAGFRRQGIGGPRPSFPYGNMADXXXXXXXXXXXXXXXXXXXIVHDYRPAVLP 349 W P+R+ R+QG G F G++ + +D P ++P Sbjct: 32 WFTPKRIEKRLRQQGFRGNPYRFLVGDVKESGKMHQEALSKPMEFN-----NDIVPRLMP 86 Query: 350 FYEKWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKA--THEPLFG- 520 +G MG + +HV P++++++ S Y K H PL Sbjct: 87 HINHTINTYGRNSFTWMGRIPRIHVMEPELIKEVLT------HSSKYQKNFDVHNPLVKF 140 Query: 521 --RGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDI 694 G+ G W+ R+II+P F L+K+K M+ +L WE +K G ++ Sbjct: 141 LLTGVGSFEGAKWSKHRRIISPAFTLEKLKSMLPAFAICYHDMLTKWEKIAEKQGSH-EV 199 Query: 695 KIDDDIRAYSADVISRTCFGSSYVKGKKIFLKLRELQKAVSKPNVLAEMTGLRFFPTKKN 874 I ++DVIS+ FGS+Y +G KIF L+EL + G + PTK+N Sbjct: 200 DIFPTFDVLTSDVISKVAFGSTYEEGGKIFRLLKELMDLTIDCMRDVYIPGWSYLPTKRN 259 Query: 875 RQAWGLHKQVHRLILEIVK---------ESGEDKNLLRAILHS------ASSSKVGLGEA 1009 ++ ++K++ ++ I+ E GED +LL +L S +K G + Sbjct: 260 KRMKEINKEITDMLRFIINKRMKALKAGEPGED-DLLGVLLESNIQEIQKQGNKKDGGMS 318 Query: 1010 ENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGRPLDSQSLQK 1189 N +++ CK YFAG E+T V W +LL HPEWQ+R R+EVL+ G + + L Sbjct: 319 INDVIEECKLFYFAGQETTGVLLTWTTILLSKHPEWQERAREEVLQAFGKNKPEFERLNH 378 Query: 1190 MKNLTMVIQETLRLYPAGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWGPDA 1369 +K ++M++ E LRLYP ++++ ++ KLG IP G + +P +H + +WG DA Sbjct: 379 LKYVSMILYEVLRLYPPVIDLTKIVHKDTKLGSYTIPAGTQVMLPTVMLHREKSIWGEDA 438 Query: 1370 KEFNPARFSD----ARPQLHSYLPFGAGARTCLGQGFATAEXXXXXXXXXXXFALRLSPL 1537 EFNP RF D A +YLPF G R CLGQ FA + F ++P Sbjct: 439 MEFNPMRFVDGVANATKNNVTYLPFSWGPRVCLGQNFALLQAKLGLAMILQRFKFDVAPS 498 Query: 1538 YQHSPALKLIVEPEFGVDITLTKVQT 1615 Y H+P L V+P+FG + K+++ Sbjct: 499 YVHAPFTILTVQPQFGSHVIYKKLES 524
>Q29496:CP3AO_SHEEP Cytochrome P450 3A24 - Ovis aries (Sheep)| Length = 503 Score = 152 bits (383), Expect = 6e-36 Identities = 126/453 (27%), Positives = 214/453 (47%), Gaps = 29/453 (6%) Frame = +2 Query: 200 FRRQGIGGPRPSFPYGNMADXXXXXXXXXXXXXXXXXXXIVHDYRPAVLPFYEKWRKEHG 379 F++ G+ GPRP +GN V YR V F E+ K++G Sbjct: 33 FKKLGVSGPRPLPYFGN-----------------------VLSYRKGVCEFDEECFKKYG 69 Query: 380 PVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFG-RGILKS-----N 541 ++ G L ++ PDV++ + L K Y T+ +FG GI+K+ Sbjct: 70 KMWGVFEGKQPLLVITDPDVIKTV-------LVKECYSVFTNRRVFGPMGIMKNAVSVAE 122 Query: 542 GEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAY 721 E W R +++P F K+K M ++ L+ +K G +V++K D AY Sbjct: 123 DEQWKRIRTLLSPTFTSGKLKDMFPIIGKYGDVLVRNLRKEAEK-GKSVNMK--DIFGAY 179 Query: 722 SADVISRTCFGSS----------YVKGKKIFLKLRELQ----KAVSKPNVLA--EMTGLR 853 S DVI+ T FG + +V+ K L+ L V P ++ E+ + Sbjct: 180 SMDVITSTSFGVNIDSLGNPQDPFVENAKKLLRFNILDPFLLSVVLFPFLVPIFEVLNIT 239 Query: 854 FFPTKKNRQAWGLHKQVHRLILEIVKESGEDK-NLLRAILHSASSSKVGLGEA--ENFIV 1024 FP L K V R+ +K++ + + + L+ +++S +S + +A + ++ Sbjct: 240 MFPKSA---VDFLTKSVKRIKESRLKDNQKPRVDFLQLMINSQNSKETDNHKALSDQELM 296 Query: 1025 DNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGR-PLDSQSLQKMKNL 1201 FAGYE+T+ T ++ L +L HP+ Q ++++E+ + P L +M+ L Sbjct: 297 AQSVIFIFAGYETTSNTLSFLLYILATHPDVQQKLQEEIDATFPNKAPPTYDVLAQMEYL 356 Query: 1202 TMVIQETLRLYPAGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFN 1381 MV+ ETLR++P + R+ +++++ GV IPKG + +P+ +H DP+LW P+ +EF Sbjct: 357 DMVVNETLRMFPIAVRLDRLCKKDVEIHGVSIPKGTAVTVPIFVLHRDPQLW-PEPEEFR 415 Query: 1382 PARFSDARPQL---HSYLPFGAGARTCLGQGFA 1471 P RFS + YLPFG G R C+G FA Sbjct: 416 PERFSKKNKDSINPYVYLPFGTGPRNCIGMRFA 448
>P79102:CP3AS_BOVIN Cytochrome P450 3A28 - Bos taurus (Bovine)| Length = 507 Score = 140 bits (352), Expect = 2e-32 Identities = 121/462 (26%), Positives = 210/462 (45%), Gaps = 38/462 (8%) Frame = +2 Query: 200 FRRQGIGGPRPSFPYGNMADXXXXXXXXXXXXXXXXXXXIVHDYRPAVLPFYEKWRKEHG 379 F++ GI GPRP +G+ Y + F + K++G Sbjct: 33 FKKLGIPGPRPVPYFGSTMA-----------------------YHKGIPEFDNQCFKKYG 69 Query: 380 PVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFG-RGILK-----SN 541 ++ + G L ++ PD+++ + L K Y T+ +FG GI+K + Sbjct: 70 KMWGFYEGRQPMLAITDPDIIKTV-------LVKECYSVFTNRRIFGPMGIMKYAISLAW 122 Query: 542 GEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAY 721 E W R +++P F K+K M ++ L+ +K G V++K D AY Sbjct: 123 DEQWKRIRTLLSPAFTSGKLKEMFPIIGQYGDMLVRNLRKEAEK-GNPVNMK--DMFGAY 179 Query: 722 SADVISRTCFGSS----------YVKGKKIFLKLRELQKAVSKP------NVLAEMTGLR 853 S DVI+ T FG + +V+ K L+ R + N + E+ + Sbjct: 180 SMDVITGTAFGVNIDSLNNPHDPFVEHSKNLLRFRPFDPFILSIILFPFLNPVFEILNIT 239 Query: 854 FFP----------TKKNRQAWGLHKQVHRLILEIVKESGEDKNLLRAILHSASSSKVGLG 1003 FP KK +++ KQ++R+ +LL+ +++S +S ++ Sbjct: 240 LFPKSTVDFFTKSVKKIKESRLTDKQMNRV------------DLLQLMINSQNSKEIDNH 287 Query: 1004 EAENFI--VDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGR-PLDS 1174 +A + I V F GYE+T+ T ++ + L HP Q ++++E+ + P Sbjct: 288 KALSDIELVAQSTIFIFGGYETTSSTLSFIIYELTTHPHVQQKLQEEIDATFPNKAPPTY 347 Query: 1175 QSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKL 1354 +L +M+ L MV+ ETLR++P + R+ +++++ GV IPKG + +P+ +H +P+L Sbjct: 348 DALVQMEYLDMVVNETLRMFPIAGRLERVCKKDVEIHGVTIPKGTTVLVPLFVLHNNPEL 407 Query: 1355 WGPDAKEFNPARFSDARPQL---HSYLPFGAGARTCLGQGFA 1471 W P+ +EF P RFS + YLPFG G R CLG FA Sbjct: 408 W-PEPEEFRPERFSKNNKDSINPYVYLPFGTGPRNCLGMRFA 448
>P11707:CP3A6_RABIT Cytochrome P450 3A6 - Oryctolagus cuniculus (Rabbit)| Length = 501 Score = 140 bits (352), Expect = 2e-32 Identities = 118/408 (28%), Positives = 201/408 (49%), Gaps = 26/408 (6%) Frame = +2 Query: 326 DYRPAVLPFYEKWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATH 505 +YR + F + RK++G ++ G + ++ PD+++ + L K Y T+ Sbjct: 50 EYRKGIWDFDIECRKKYGKMWGLFDGRQPLMVITDPDMIKTV-------LVKECYSVFTN 102 Query: 506 EPLFGR-GILK-----SNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARV 667 FG G +K S E W R +++P F K+K M+ ++ L++ Sbjct: 103 RRSFGPVGFMKKAVSISEDEDWKRVRTLLSPTFTSGKLKEMLPIIAQYGDVLVKNLRQEA 162 Query: 668 DKSGGTVDIKIDDDIRAYSADVISRTCFG---SSYVKGKKIFLK-LRELQKAVSKPNVLA 835 +K G VD+K + AYS DVI+ T FG S + F+K +R L K +L Sbjct: 163 EK-GKPVDLK--EIFGAYSMDVITGTSFGVNIDSLRNPQDPFVKNVRRLLKFSFFDPLLL 219 Query: 836 EMTGLRFF-PTKKNRQAWGLHKQVHRLILEIVKESGEDK---------NLLRAILHSASS 985 +T F P + K V + V++ +D+ + L+ +++S +S Sbjct: 220 SITLFPFLTPIFEALHISMFPKDVMDFLKTSVEKIKDDRLKDKQKRRVDFLQLMINSQNS 279 Query: 986 SKVGLGEAENFIVDNCKSIY--FAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGG 1159 ++ +A + I +SI FAGYE+T+ T ++ + LL HP+ Q ++++E+ + Sbjct: 280 KEIDSHKALDDIEVVAQSIIILFAGYETTSSTLSFIMHLLATHPDVQQKLQEEIDTLLPN 339 Query: 1160 RPLDS-QSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKLGGVHIPKGVNIYIPVSTM 1336 + L + +L KM+ L MV+ ETLRLYP + R+ +++ + G IPKG + +P + Sbjct: 340 KELATYDTLVKMEYLDMVVNETLRLYPIAGRLERVCKKDVDINGTFIPKGTIVMMPTYAL 399 Query: 1337 HLDPKLWGPDAKEFNPARFSDA-RPQLHSYL--PFGAGARTCLGQGFA 1471 H DP+ W + EF P RFS + ++ Y+ PFGAG R CLG FA Sbjct: 400 HRDPQHW-TEPDEFRPERFSKKNKDNINPYIYHPFGAGPRNCLGMRFA 446
>P24463:CP3AC_CANFA Cytochrome P450 3A12 - Canis familiaris (Dog)| Length = 503 Score = 139 bits (349), Expect = 5e-32 Identities = 124/453 (27%), Positives = 212/453 (46%), Gaps = 36/453 (7%) Frame = +2 Query: 329 YRPAVLPFYEKWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINL--CVSL-----DLGKSS 487 YR F K ++G ++ + G L ++ PD+++ + + C S+ LG Sbjct: 53 YRNGFYVFDMKCFSKYGRMWGFYDGRQPVLAITDPDMIKTVLVKECYSVFTNRRTLGPVG 112 Query: 488 YLKATHEPLFGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARV 667 ++K+ I S E W R +++P F K+K M ++ L+ Sbjct: 113 FMKSA--------ISLSEDEEWKRMRTLLSPTFTTGKLKEMFPIIGQYGDVLVNNLRKEA 164 Query: 668 DKSGGTVDIKIDDDIRAYSADVISRTCFGSS----------YVKGKKIFLKLRELQKAVS 817 +K G +++K D AYS DVI+ T FG + +V+ K LK L Sbjct: 165 EK-GKAINLK--DVFGAYSMDVITSTSFGVNIDSLNHPQDPFVENTKKLLKFDFLDPFFF 221 Query: 818 KPNVLAEMTGLRFFPTKKNRQAWGLHKQV---HRLILEIVKESG-EDK-----NLLRAIL 970 + +T P + W K+V R +E +KES +DK + L+ ++ Sbjct: 222 SILLFPFLT-----PVFEILNIWLFPKKVTDFFRKSVERMKESRLKDKQKHRVDFLQLMI 276 Query: 971 HSASSSKVGLGEAENFIVDNCKSIYF--AGYESTAVTAAWCLMLLGLHPEWQDRVRQEVL 1144 +S +S ++ +A + + +SI F AGYE+T+ + ++ + L HP+ Q ++++E+ Sbjct: 277 NSQNSKEMDTHKALSDLELVAQSIIFIFAGYETTSTSLSFLMYELATHPDVQQKLQEEID 336 Query: 1145 EVCGGRPLDS-QSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKLGGVHIPKGVNIYI 1321 + L + +L +M+ L MV+ ETLRLYP + R+ +++++ GV IPKG + + Sbjct: 337 ATFPNKALPTYDALVQMEYLDMVLNETLRLYPIAGRLERVCKKDVEISGVFIPKGTVVMV 396 Query: 1322 PVSTMHLDPKLWGPDAKEFNPARFSDARPQL---HSYLPFGAGARTCLGQGFATAEXXXX 1492 P T+H D LW P+ +EF P RFS ++YLPFG G R C+G FA Sbjct: 397 PTFTLHRDQSLW-PEPEEFRPERFSRKNKDSINPYTYLPFGTGPRNCIGMRFAIMNMKLA 455 Query: 1493 XXXXXXXFALRLSPLYQHSPALKL----IVEPE 1579 F+ + P + LKL I++PE Sbjct: 456 LVRVLQNFSFK--PCKETQIPLKLNAQGIIQPE 486
>P20815:CP3A5_HUMAN Cytochrome P450 3A5 - Homo sapiens (Human)| Length = 502 Score = 139 bits (349), Expect = 5e-32 Identities = 131/469 (27%), Positives = 208/469 (44%), Gaps = 28/469 (5%) Frame = +2 Query: 149 LYLYYTVWVVPQRLLAGFRRQGIGGPRPSFPYGNMADXXXXXXXXXXXXXXXXXXXIVHD 328 LYLY T R F+R GI GP P GN V Sbjct: 22 LYLYGT------RTHGLFKRLGIPGPTPLPLLGN-----------------------VLS 52 Query: 329 YRPAVLPFYEKWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHE 508 YR + F + K++G ++ G + L ++ PDV+R + L K Y T+ Sbjct: 53 YRQGLWKFDTECYKKYGKMWGTYEGQLPVLAITDPDVIRTV-------LVKECYSVFTNR 105 Query: 509 PLFGR-GILKS-----NGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVD 670 G G +KS E W R +++P F K+K M ++ L+ + Sbjct: 106 RSLGPVGFMKSAISLAEDEEWKRIRSLLSPTFTSGKLKEMFPIIAQYGDVLVRNLRREAE 165 Query: 671 KSGGTVDIKIDDDIRAYSADVISRTCFGSS----------YVKGKKIFLKLRELQKAVSK 820 K G V +K D AYS DVI+ T FG + +V+ K FLK L Sbjct: 166 K-GKPVTLK--DIFGAYSMDVITGTSFGVNIDSLNNPQDPFVESTKKFLKFGFLDPLFLS 222 Query: 821 PNVLAEMT------GLRFFPTKKNRQAWGLHKQVHRLILEIVKESGEDK-NLLRAILHSA 979 + +T + FP L K V+R+ + + + + + L+ ++ S Sbjct: 223 IILFPFLTPVFEALNVSLFPKDTINF---LSKSVNRMKKSRLNDKQKHRLDFLQLMIDSQ 279 Query: 980 SSSKVGLGEAENFIVDNCKSIYF--AGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVC 1153 +S + +A + + +SI F AGYE+T+ ++ L L HP+ Q ++++E+ V Sbjct: 280 NSKETESHKALSDLELAAQSIIFIFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVL 339 Query: 1154 GGR-PLDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKLGGVHIPKGVNIYIPVS 1330 + P ++ +M+ L MV+ ETLRL+P + R +++++ GV IPKG + IP Sbjct: 340 PNKAPPTYDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTY 399 Query: 1331 TMHLDPKLWGPDAKEFNPARFSDARPQLHSYL--PFGAGARTCLGQGFA 1471 +H DPK W + +EF P RFS + + Y+ PFG G R C+G FA Sbjct: 400 ALHHDPKYW-TEPEEFRPERFSKKKDSIDPYIYTPFGTGPRNCIGMRFA 447
>Q9HCS2:CP4FC_HUMAN Cytochrome P450 4F12 - Homo sapiens (Human)| Length = 524 Score = 138 bits (348), Expect = 6e-32 Identities = 107/395 (27%), Positives = 183/395 (46%), Gaps = 30/395 (7%) Frame = +2 Query: 386 FTYSMGNVV-FLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRGILKSNGEAWAHQ 562 FT +G ++ F+ + PD +R I + K + +P G GIL S G+ W+ Sbjct: 88 FTVWLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKPWLGEGILLSGGDKWSRH 147 Query: 563 RKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAYSADVISR 742 R+++ P F + +K + + SA +L+ W+ + +D+ + I + D + + Sbjct: 148 RRMLTPAFHFNILKSYITIFNKSANIMLDKWQHLASEGSSRLDMF--EHISLMTLDSLQK 205 Query: 743 TCFGSS---YVKGKKIFLKLRELQKAVSK--PNVLAEMTGLRFFPTKKNRQAWGLHKQVH 907 F + + + EL V K ++L M L ++ + R+ + VH Sbjct: 206 CIFSFDSHCQERPSEYIATILELSALVEKRSQHILQHMDFL-YYLSHDGRRFHRACRLVH 264 Query: 908 RL----------------ILEIVKESGEDKNLLRAILHSASSSKVGLGEAENFIVDNCKS 1039 I + K+ + K L + S + G ++ I + Sbjct: 265 DFTDAVIRERRRTLPTQGIDDFFKDKAKSKTLDFIDVLLLSKDEDGKALSDEDIRAEADT 324 Query: 1040 IYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGR---PLDSQSLQKMKNLTMV 1210 F G+++TA +W L L HPE+Q+R RQEV E+ R ++ L ++ LTM Sbjct: 325 FMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELLKDRDPKEIEWDDLAQLPFLTMC 384 Query: 1211 IQETLRLYPAGAFVSRMALQELKL-GGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPA 1387 ++E+LRL+P F+SR Q++ L G IPKG+ I + +H +P +W PD + ++P Sbjct: 385 VKESLRLHPPAPFISRCCTQDIVLPDGRVIPKGITCLIDIIGVHHNPTVW-PDPEVYDPF 443 Query: 1388 RF----SDARPQLHSYLPFGAGARTCLGQGFATAE 1480 RF S R L +++PF AG R C+GQ FA AE Sbjct: 444 RFDPENSKGRSPL-AFIPFSAGPRNCIGQAFAMAE 477
>P29981:CP4C1_BLADI Cytochrome P450 4C1 - Blaberus discoidalis (Tropical cockroach)| Length = 511 Score = 137 bits (344), Expect = 2e-31 Identities = 121/472 (25%), Positives = 209/472 (44%), Gaps = 49/472 (10%) Frame = +2 Query: 332 RPAVLPFYEKWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEP 511 R + +++ K +GP++ G + + ++RP+ V ++ L + + KS + + P Sbjct: 56 RNKLFQVFDRRAKLYGPLYRIWAGPIAQVGLTRPEHV-ELILRDTKHIDKS-LVYSFIRP 113 Query: 512 LFGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVD 691 G G+L G W RK+I P F + VD+ V+ ++ L++ +++V G D Sbjct: 114 WLGEGLLTGTGAKWHSHRKMITPTFHFKILDIFVDVFVEKSEILVKKLQSKV----GGKD 169 Query: 692 IKIDDDIRAYSADVISRTCFG----------SSYVK------------------------ 769 I I + D+I T G S YVK Sbjct: 170 FDIYPFITHCALDIICETAMGIQMNAQEESESEYVKAVYEISELTMQRSVRPWLHPKVIF 229 Query: 770 -----GKKIFLKLREL----QKAVSKPNVLAEMTGLRFFPTKKNRQAWGLHKQVHRLILE 922 GK+ LR L K + + L +MTG++ PT N + L K+ L+ Sbjct: 230 DLTTMGKRYAECLRILHGFTNKVIQERKSLRQMTGMK--PTISNEEDELLGKKKRLAFLD 287 Query: 923 IVKESGEDKNLLRAILHSASSSKVGLGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLG 1102 ++ E+ E+ G ++ I + + F G+++T+ W L LLG Sbjct: 288 LLLEASEN----------------GTKMSDTDIREEVDTFMFEGHDTTSAGICWALFLLG 331 Query: 1103 LHPEWQDRVRQEVLEVCGG--RPLDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQEL 1276 HPE QD+V +E+ + G R + L MK L VI+E+LRL+P+ F+ R+ ++ Sbjct: 332 SHPEIQDKVYEELDHIFQGSDRSTTMRDLADMKYLERVIKESLRLFPSVPFIGRVLKEDT 391 Query: 1277 KLGGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARFSD---ARPQLHSYLPFGAGAR 1447 K+G +P G + + + +H + + P+ + FNP F A+ ++Y+PF AG R Sbjct: 392 KIGDYLVPAGCMMNLQIYHVHRNQDQY-PNPEAFNPDNFLPERVAKRHPYAYVPFSAGPR 450 Query: 1448 TCLGQGFATAEXXXXXXXXXXXFALRLSPLYQHSPAL-KLIVEPEFGVDITL 1600 C+GQ FAT E F +R + + +LI+ PE G+ + L Sbjct: 451 NCIGQKFATLEEKTVLSSILRNFKVRSIEKREDLTLMNELILRPESGIKVEL 502
>P24464:CP4AC_RAT Cytochrome P450 4A12 - Rattus norvegicus (Rat)| Length = 508 Score = 136 bits (342), Expect = 3e-31 Identities = 113/428 (26%), Positives = 188/428 (43%), Gaps = 24/428 (5%) Frame = +2 Query: 401 GNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRGILKSNGEAWAHQRKIIAP 580 G+ V + V PD ++ L + KS + P G G+L NG+ W R+++ P Sbjct: 90 GSNVRIQVYDPDYMK---LILGRSDPKSHHSYRFLAPWIGYGLLLLNGQTWFQHRRMLTP 146 Query: 581 EFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAYSADVISRTCFGSS 760 F D +K V +M DS + +L+ WE V G ++I I + D I + F S Sbjct: 147 AFHYDTLKPYVGIMADSVRIMLDKWEQIV---GQDSTLEIFQHITLMTLDTIMKCAF--S 201 Query: 761 YVKGKKIFLKLRELQKAVSKPNVLAEMTGLRFFPT-----------KKNRQAWGLHKQVH 907 ++ K + KAV N L+ F +K R AW L + Sbjct: 202 QEGSVQLDRKYKSYIKAVEDLNNLSFFRIRNIFHQNDIIYSLSSNGRKARSAWQLAHEHT 261 Query: 908 RLILEIVKESGEDKNLLRAILHSA----------SSSKVGLGEAENFIVDNCKSIYFAGY 1057 +++ K +D+ L+ + + + G ++ + + F G+ Sbjct: 262 DQVIKSRKAQLQDEEELQKVKQKRRLDFLDILLFARIENGSSLSDKDLRAEVDTFMFEGH 321 Query: 1058 ESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCG-GRPLDSQSLQKMKNLTMVIQETLRLY 1234 ++TA +W L +PE Q R+E+ + G G + L KM TM I+E LR+Y Sbjct: 322 DTTASGISWIFYALATNPEHQQGCRKEIQSLLGDGASITWDDLDKMPYTTMCIKEALRIY 381 Query: 1235 PAGAFVSRMALQELKL-GGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARFS-DARP 1408 P VSRM + G +PKG+ + + +H +P +W P+ + F+P RF+ ++ Sbjct: 382 PPVTAVSRMLSTPVTFPDGRSLPKGITVMLSFYGLHHNPTVW-PNPEVFDPYRFAPESSR 440 Query: 1409 QLHSYLPFGAGARTCLGQGFATAEXXXXXXXXXXXFALRLSPLYQHSPALKLIVEPEFGV 1588 HS+LPF GAR C+G+ FA E F L P P +L+++ + G+ Sbjct: 441 HSHSFLPFSGGARNCIGKQFAMNELKVAVALTLLRFELLPDPTRIPIPIPRLVLKSKNGI 500 Query: 1589 DITLTKVQ 1612 + L K+Q Sbjct: 501 YLRLKKLQ 508
>P14579:CP4A5_RABIT Cytochrome P450 4A5 precursor - Oryctolagus cuniculus (Rabbit)| Length = 511 Score = 135 bits (339), Expect = 7e-31 Identities = 114/437 (26%), Positives = 193/437 (44%), Gaps = 33/437 (7%) Frame = +2 Query: 401 GNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRGILKSNGEAWAHQRKIIAP 580 GN V + + PD ++ I L S + SY P G G+L NG+ W R+++ P Sbjct: 92 GNKVRVQLYDPDYMKVI-LGRSDPKSRGSYTFVA--PWIGYGLLLLNGQPWFQHRRMLTP 148 Query: 581 EFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAYSADVISRTCFG-- 754 F D +K V LMVDS Q +L+ WE V + +++ DI + D I + F Sbjct: 149 AFHYDILKPYVGLMVDSVQIMLDKWEQLVSQDSS---LEVFQDISLMTLDTIMKCAFSYQ 205 Query: 755 ----------SSYVKG-----KKIFLKLRELQKAVSKPNVLAEMTGLRFFPTKK--NRQA 883 SY++ +F ++R + T R P + +R Sbjct: 206 GSVQLDSRNSQSYIQAVGDLNNLVFARVRNIFHQSD--------TIYRLSPEGRLSHRAC 257 Query: 884 WGLHKQVHRLILEI---VKESGEDKNLLR--------AILHSASSSKVGLGEAENFIVDN 1030 H+ R+I + +++ GE + + R +L + + L + + + Sbjct: 258 QLAHEHTDRVIQQRKAQLQQEGELEKVRRKRRLDFLDVLLFAKMENGSSLSDQD--LRAE 315 Query: 1031 CKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCG-GRPLDSQSLQKMKNLTM 1207 + F G+++TA +W L HPE Q R R+E+ + G G + + L +M TM Sbjct: 316 VDTFMFEGHDTTASGVSWIFYALATHPEHQHRCREEIQGLLGDGASITWEHLDQMPYTTM 375 Query: 1208 VIQETLRLYPAGAFVSRMALQELKL-GGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNP 1384 I+E +RLYP +SR + G +PKG + + + +H +P +W P+ + F+P Sbjct: 376 CIKEAMRLYPPVPAISRDLSSPVTFPDGRSLPKGFTVTLSIYGLHHNPNVW-PNPEVFDP 434 Query: 1385 ARFSDARPQ-LHSYLPFGAGARTCLGQGFATAEXXXXXXXXXXXFALRLSPLYQHSPALK 1561 RF+ + H++LPF GAR C+G+ FA E F L P P + Sbjct: 435 GRFTPGSARHSHAFLPFSGGARNCIGKQFAMNELKVAVALTLVRFELLPDPTRIPKPTAR 494 Query: 1562 LIVEPEFGVDITLTKVQ 1612 L+++ G+ + L K+Q Sbjct: 495 LVLKSNNGIHLRLRKLQ 511
>P79401:CP3AT_PIG Cytochrome P450 3A29 - Sus scrofa (Pig)| Length = 503 Score = 135 bits (339), Expect = 7e-31 Identities = 122/454 (26%), Positives = 204/454 (44%), Gaps = 30/454 (6%) Frame = +2 Query: 200 FRRQGIGGPRPSFPYGNMADXXXXXXXXXXXXXXXXXXXIVHDYRPAVLPFYEKWRKEHG 379 F++ GI GPRP +GN+ YR V F +K +++G Sbjct: 33 FKKLGIPGPRPLPYFGNILG-----------------------YRKGVDHFDKKCFQQYG 69 Query: 380 PVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFG------RGILKSN 541 ++ G L V+ P++++ + L K Y T+ FG + + Sbjct: 70 KMWGVYDGRQPLLAVTDPNMIKSV-------LVKECYSVFTNRRSFGPLGAMRNALSLAE 122 Query: 542 GEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAY 721 E W R +++P F K+K M ++ L+ +K G V +K D AY Sbjct: 123 DEEWKRIRTLLSPTFTSGKLKEMFPIISHYGDLLVSNLRKEAEK-GKPVTMK--DIFGAY 179 Query: 722 SADVISRTCFGSS----------YVKGKKIFLKLRE----LQKAVSKPNV--LAEMTGLR 853 S DVI+ T FG + +V+ K LK L + P + + E+ + Sbjct: 180 SMDVITSTAFGVNIDSLNNPQDPFVENSKKLLKFSFFDPFLLSLIFFPFLTPIFEVLNIT 239 Query: 854 FFPTKKNRQAWGLHKQVHRLILEIVKESGEDK-NLLRAILHSASSSKVGLGEA---ENFI 1021 FP K V R+ + + + + +LL+ +++S +S ++ ++ E + Sbjct: 240 LFPKSSVNF---FTKSVKRMKESRLTDQQKRRVDLLQLMINSQNSKEMDPHKSLSNEELV 296 Query: 1022 VDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGR-PLDSQSLQKMKN 1198 I FAGYE+T+ + L HP+ Q ++++E+ + P +L +M+ Sbjct: 297 AQGIIFI-FAGYETTSSALSLLAYELATHPDVQQKLQEEIEATFPNKAPPTYDALAQMEY 355 Query: 1199 LTMVIQETLRLYPAGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEF 1378 L MV+ ETLRLYP A + R +++++ GV +PKG + +PV +H DP LW P+ +EF Sbjct: 356 LDMVVNETLRLYPIAARLERACKKDVEIHGVFVPKGTVVVVPVFVLHRDPDLW-PEPEEF 414 Query: 1379 NPARFSDARPQL---HSYLPFGAGARTCLGQGFA 1471 P RFS ++YLPFG G R C+G FA Sbjct: 415 RPERFSKKHKDTINPYTYLPFGTGPRNCIGMRFA 448
>Q64581:CP3AI_RAT Cytochrome P450 3A18 - Rattus norvegicus (Rat)| Length = 497 Score = 135 bits (339), Expect = 7e-31 Identities = 120/456 (26%), Positives = 208/456 (45%), Gaps = 32/456 (7%) Frame = +2 Query: 200 FRRQGIGGPRPSFPYGNMADXXXXXXXXXXXXXXXXXXXIVHDYRPAVLPFYEKWRKEHG 379 F++ GI GP+P +G + +Y + F + K++G Sbjct: 33 FKKLGIPGPKPVPLFGT-----------------------IFNYGDGMWKFDDDCYKKYG 69 Query: 380 PVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFG------RGILKSN 541 ++ + G FL + P++++ + L K Y T+ FG + I S Sbjct: 70 KIWGFYEGPQPFLAIMDPEIIKMV-------LVKECYSVFTNRRCFGPMGFMKKAITMSE 122 Query: 542 GEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAY 721 E W R I++P F K+K M LM TLL+ R + G +++K D AY Sbjct: 123 DEEWKRLRTILSPTFTSGKLKEMFPLMRQYGDTLLKNLR-REEAKGEPINMK--DIFGAY 179 Query: 722 SADVISRTCFGSS----------YVKGKKIFLKLRE----LQKAVSKPNV--LAEMTGLR 853 S DVI+ T FG + +V+ K LK + L V P + + EM Sbjct: 180 SMDVITGTSFGVNVDSLNNPQDPFVQKAKKILKFQIFDPFLLSVVLFPFLTPIYEMLNFS 239 Query: 854 FFPTKKNRQAWGLHKQVHRLILEIVKESGEDKNL--LRAILHSASS----SKVGLGEAEN 1015 FP RQ+ K+ + + + +S + + L+ ++++ +S S+ L + E Sbjct: 240 IFP----RQSMNFFKKFVKTMKKNRLDSNQKNRVDFLQLMMNTQNSKGQESQKALSDLE- 294 Query: 1016 FIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGR-PLDSQSLQKM 1192 + F GY++T+ + ++ + L P Q +++ E+ + P+ +L +M Sbjct: 295 -MAAQAIIFIFGGYDATSTSISFIMYELATRPNVQKKLQNEIDRALPNKAPVTYDALMEM 353 Query: 1193 KNLTMVIQETLRLYPAGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWGPDAK 1372 + L MV+ E+LRLYP + R++ +++++ GV IPKG + IP+ +H +P+ W + + Sbjct: 354 EYLDMVVNESLRLYPIATRLDRVSKKDVEINGVFIPKGTVVTIPIYPLHRNPEYW-LEPE 412 Query: 1373 EFNPARFSDARP---QLHSYLPFGAGARTCLGQGFA 1471 EFNP RFS + YLPFG G R C+G FA Sbjct: 413 EFNPERFSKENKGSIDPYVYLPFGNGPRNCIGMRFA 448
>Q9DBW0:CP4V3_MOUSE Cytochrome P450 4V3 - Mus musculus (Mouse)| Length = 525 Score = 134 bits (336), Expect = 2e-30 Identities = 114/400 (28%), Positives = 189/400 (47%), Gaps = 31/400 (7%) Frame = +2 Query: 374 HGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRGILKSNGEAW 553 H P+ +G V + + + + V ++ L S + KS +L +P G G+L S G W Sbjct: 86 HLPIIKLWIGPVPLVALYKAENV-EVILTSSKQIDKS-FLYKFLQPWLGLGLLTSTGSKW 143 Query: 554 AHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAYSADV 733 +RK++ P F ++ +D+M + A L+ E V++ I + D+ Sbjct: 144 RTRRKMLTPTFHFTILENFLDVMNEQANILVNKLEKHVNQEAFNCFFYIT----LCALDI 199 Query: 734 ISRTCFG----------SSYVKGKKIFLKLRELQKAVSKPNVLAEMTGLRFFPTKKNRQA 883 I T G S YV+ ++ + + + P + ++ L F + +++ Sbjct: 200 ICETAMGKNIGAQSNNDSEYVR--TVYRMSDMIYRRMKMPWLWFDLWYLVFKEGRDHKRG 257 Query: 884 WG-LHKQVHRLILEIVKE--SGED-----------KNLLRAILHSASS--SKVGLGEAEN 1015 LH + +I E VKE + ED KN +A L S + G ++ Sbjct: 258 LKCLHTFTNNVIAERVKERKAEEDWTGAGRGPIPSKNKRKAFLDLLLSVTDEEGNRLSQE 317 Query: 1016 FIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGG--RPLDSQSLQK 1189 I + + F G+++TA W L LLG +PE Q +V QE+ EV G RP+ + L+K Sbjct: 318 DIREEVDTFMFEGHDTTAAAINWSLYLLGTNPEVQRKVDQELDEVFGRSHRPVTLEDLKK 377 Query: 1190 MKNLTMVIQETLRLYPAGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWGPDA 1369 +K L VI+ETLR++P+ +R ++ ++GG + KG I +H DP+ + PD Sbjct: 378 LKYLDCVIKETLRVFPSVPLFARSLSEDCEVGGYKVTKGTEAIIIPYALHRDPRYF-PDP 436 Query: 1370 KEFNPARFSDARPQ---LHSYLPFGAGARTCLGQGFATAE 1480 +EF P RF Q ++Y+PF AG R C+GQ FA E Sbjct: 437 EEFRPERFFPENSQGRHPYAYVPFSAGPRNCIGQKFAVME 476
>O18993:CP3AL_CALJA Cytochrome P450 3A21 - Callithrix jacchus (Common marmoset)| Length = 503 Score = 134 bits (336), Expect = 2e-30 Identities = 121/460 (26%), Positives = 207/460 (45%), Gaps = 41/460 (8%) Frame = +2 Query: 329 YRPAVLPFYEKWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHE 508 YR F + K++G ++ G L ++ P++++ + L K Y T+ Sbjct: 53 YRQGFWKFDMECYKKYGKMWGIYDGRQPVLAITDPNIIKTV-------LVKECYSVFTNR 105 Query: 509 PLFGR-GILKS-----NGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVD 670 FG G +KS + W R +++P F K+K MV ++ + L+ + Sbjct: 106 RPFGPVGFMKSAISIAQDDEWKRIRSLLSPTFTSGKLKEMVPIIAQYGEVLVRNLRREAE 165 Query: 671 KSGGTVDIKIDDDIRAYSADVISRTCFGSS----------YVKGKKIFLKLRELQKAVSK 820 K G +++K D AYS DVI+ T FG + +V+ K L+ L Sbjct: 166 K-GKPINMK--DIFGAYSMDVITGTSFGVNIDSLNNPQDPFVESTKKLLRFDFLDPFFLS 222 Query: 821 PNV------LAEMTGLRFFPTKKNRQAWGLHKQVHRLILEIVKESGEDK-NLLRAILHSA 979 + + E + FP L K + R+ +K++ + + + L+ ++ S Sbjct: 223 ITIFPFLTPILEALNISMFPRDSTSF---LRKSIKRIKESRLKDTHKHRVDFLQLMIDSQ 279 Query: 980 SSSKVGLGEAENFIVDNCKSIYF--AGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVC 1153 +S + +A + + +SI F AGYE+T+ T ++ + L HP+ Q ++++E+ V Sbjct: 280 NSKETESDKALSDLELVAQSIIFIFAGYETTSSTLSFIMYELATHPDVQQKLQEEIDAVL 339 Query: 1154 GGR-PLDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKLGGVHIPKGVNIYIPVS 1330 + P ++ +M+ L MV+ ETLRL+P + R+ +++++ GV IPKGV + IP Sbjct: 340 PNKAPATYDTVLQMEYLDMVVNETLRLFPLAMRLERVCKKDVEINGVFIPKGVVVMIPSY 399 Query: 1331 TMHLDPKLWGPDAKEFNPARFSDARP---QLHSYLPFGAGARTCLGQGFATAEXXXXXXX 1501 +H DPK W + ++F P RFS + Y PFG G R C+G FA Sbjct: 400 ALHYDPKYW-TEPEKFLPERFSKNNKDNIDPYIYTPFGTGPRNCIGMRFALMNMKLALIR 458 Query: 1502 XXXXFA------------LRLSPLYQHSPALKLIVEPEFG 1585 F+ LRL L Q + L VEP G Sbjct: 459 VLQNFSFKPCKETQIPLKLRLGGLLQTEKPIVLKVEPRDG 498
>Q64464:CP3AD_MOUSE Cytochrome P450 3A13 - Mus musculus (Mouse)| Length = 503 Score = 133 bits (335), Expect = 2e-30 Identities = 109/402 (27%), Positives = 177/402 (44%), Gaps = 34/402 (8%) Frame = +2 Query: 368 KEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGR-GILK--- 535 K++G ++ G L ++ PD+++ + L K Y T+ FG GILK Sbjct: 66 KKYGKMWGLYDGRQPVLAITDPDIIKTV-------LVKECYSTFTNRRRFGPVGILKKAI 118 Query: 536 --SNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDD 709 S E W R +++P F ++K M ++ L+ + + T + D Sbjct: 119 SISENEEWKRIRALLSPTFTSGRLKEMFPIINQFTDVLVRNMRQGLGEGKPT---SMKDI 175 Query: 710 IRAYSADVISRTCFGSS----------YVKGKKIFLKLRELQKAVSKPNVLAEMTG---- 847 AYS DVI+ T FG + +V+ K LK + +T Sbjct: 176 FGAYSMDVITATSFGVNIDSLNNPQDPFVEKIKKLLKFDIFDPLFLSVTLFPFLTPVFDA 235 Query: 848 ----------LRFFPTKKNRQAWGLHKQVHRLILEIVKESGEDKNLLRAILHSASSSKVG 997 + FF T R K+ + ++ ++ +N H A S Sbjct: 236 LNVSLFPRDVISFFTTSVERMKENRMKEKEKQRVDFLQLMINSQNYKTKESHKALSDVEI 295 Query: 998 LGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGR-PLDS 1174 + ++ FI FAGYE+T+ ++ L LL +HP+ Q +++ E+ + P Sbjct: 296 VAQSVIFI--------FAGYETTSSALSFALYLLAIHPDVQKKLQDEIDAALPNKAPATY 347 Query: 1175 QSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKL 1354 +L +M+ L MV+ ETLRLYP + R+ ++++ G+ IPKG + IP +H DPK Sbjct: 348 DTLLQMEYLDMVVNETLRLYPIAGRLERVCKTDVEINGLFIPKGTVVMIPTFALHKDPKY 407 Query: 1355 WGPDAKEFNPARFSDARPQL---HSYLPFGAGARTCLGQGFA 1471 W P+ +EF P RFS + YLPFG+G R C+G FA Sbjct: 408 W-PEPEEFRPERFSKKNQDSINPYMYLPFGSGPRNCIGMRFA 448
>Q8K4D6:CP4X1_RAT Cytochrome P450 4X1 - Rattus norvegicus (Rat)| Length = 507 Score = 133 bits (334), Expect = 3e-30 Identities = 107/425 (25%), Positives = 191/425 (44%), Gaps = 26/425 (6%) Frame = +2 Query: 413 FLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRGILKSNGEAWAHQRKIIAPEFFL 592 F ++ PD + + +S K+ YL P GRG+L +G W R ++ P F Sbjct: 90 FFYIYDPDYAK---IFLSRTDPKTQYLHQLMTPFLGRGLLNLDGPRWFQHRCLLTPAFHQ 146 Query: 593 DKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAYSADVISRTCFGS----- 757 D +K VD+M S +L+ WE T+++ + I + D+I + FG Sbjct: 147 DILKPCVDMMAHSVNMMLDKWEKTWTTQETTIEVF--EHINLMTLDIIMKCAFGQETNCQ 204 Query: 758 ---SYVKGKKIFLKLRELQKAVSKPNVLAEMTGLRFFPTKKNRQAWGLHKQVHRLILEIV 928 +Y K +L E+ S+ + F + K L K +H+ +I+ Sbjct: 205 INGTYESYVKATFELGEIIS--SRLYNFWHHHDIIFKLSPKGHCFQELGKVIHQCTEKII 262 Query: 929 KESGE-------------DKNLLRAILHSASSSKVGLGEAENFIVDNCKSIYFAGYESTA 1069 ++ + +N L +L + + + +A+ + + +AG++++A Sbjct: 263 QDRKKTLKDQVNQDDTQTSQNFLDIVLSAQAGDEKAFSDAD--LRSEVNTFMWAGHDASA 320 Query: 1070 VTAAWCLMLLGLHPEWQDRVRQEVLEVCG-GRPLDSQSLQKMKNLTMVIQETLRLYPAGA 1246 + +W L L L+PE QDR R E+ + G G + + L ++ TM I+ETLRL P Sbjct: 321 ASISWLLYCLALNPEHQDRCRTEIRSILGDGSSITWEQLDEIPYTTMCIKETLRLIPPIP 380 Query: 1247 FVSRMALQELKLGGVH-IPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARFS-DARPQLH- 1417 +SR + L L H +P G+ + + + +H +P +W D K F+P RF+ + Q H Sbjct: 381 SISRELSKPLTLPDGHSLPAGMTVVLSIWGLHHNPAVW-KDPKVFDPLRFTKENSEQRHP 439 Query: 1418 -SYLPFGAGARTCLGQGFATAEXXXXXXXXXXXFALRLSPLYQHSPALKLIVEPEFGVDI 1594 ++LPF +G R C+GQ FA E F + + + ++ P+ G+ + Sbjct: 440 CAFLPFSSGPRNCIGQQFAMLELKVAIALTLLRFRVAADLTRPPAFSSHTVLRPKHGIYL 499 Query: 1595 TLTKV 1609 L K+ Sbjct: 500 HLKKL 504
>Q9HB55:CP343_HUMAN Cytochrome P450 3A43 - Homo sapiens (Human)| Length = 503 Score = 133 bits (334), Expect = 3e-30 Identities = 119/450 (26%), Positives = 205/450 (45%), Gaps = 40/450 (8%) Frame = +2 Query: 350 FYEKWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHE-PLFGRG 526 F + +++G ++ G L + PD+++ + L K Y T++ PL G Sbjct: 60 FDRECNEKYGEMWGLYEGQQPMLVIMDPDMIKTV-------LVKECYSVFTNQMPLGPMG 112 Query: 527 ILKS-----NGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVD 691 LKS E W R +++P F K K MV ++ L+ + S Sbjct: 113 FLKSALSFAEDEEWKRIRTLLSPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKS--- 169 Query: 692 IKIDDDIRAYSADVISRTCFGSS----------YVKGKKIFLKLRELQKAVSKPNVLAEM 841 I + D AY+ DVI+ T FG + ++K K LKL L + ++ + Sbjct: 170 INLKDFFGAYTMDVITGTLFGVNLDSLNNPQDPFLKNMKKLLKLDFLDPFLLLISLFPFL 229 Query: 842 T------GLRFFPT----------KKNRQAWGLHKQVHRLILEIVKESGEDKNLLRAILH 973 T + FP ++ +++ KQ HR+ + ++ + +N H Sbjct: 230 TPVFEALNIGLFPKDVTHFLKNSIERMKESRLKDKQKHRV--DFFQQMIDSQNSKETKSH 287 Query: 974 SASSSKVGLGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVC 1153 A L + E +V I FA Y++T+ T + + L HP+ Q ++++E+ V Sbjct: 288 KA------LSDLE--LVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVL 339 Query: 1154 GGR-PLDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKLGGVHIPKGVNIYIPVS 1330 + P+ +L +M+ L MV+ ETLRL+P + V+R+ +++++ GV IPKG+ + +P+ Sbjct: 340 PNKAPVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIY 399 Query: 1331 TMHLDPKLWGPDAKEFNPARFSDARP---QLHSYLPFGAGARTCLGQGFATAEXXXXXXX 1501 +H DPK W + ++F P RFS L+ Y+PFGAG R C+G FA Sbjct: 400 ALHHDPKYW-TEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIR 458 Query: 1502 XXXXFALRLSPLYQHSPALKL----IVEPE 1579 F+ + P + LKL I++PE Sbjct: 459 ALQNFSFK--PCKETQIPLKLDNLPILQPE 486
>Q27514:C13A5_CAEEL Putative cytochrome P450 CYP13A5 - Caenorhabditis elegans| Length = 520 Score = 133 bits (334), Expect = 3e-30 Identities = 128/503 (25%), Positives = 220/503 (43%), Gaps = 53/503 (10%) Frame = +2 Query: 131 GACSLALYLYYTVWVVPQRLLAGFRRQGIGGPRPSFPYGNMADXXXXXXXXXXXXXXXXX 310 GA + L YY +W+ + + R+G+ GPR FP+ Sbjct: 9 GASFIGLLTYY-IWI-----WSFWIRKGVKGPR-GFPF---------------------- 39 Query: 311 XXIVHDYR----PAVLPFYEKWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLG 478 ++H+++ P +L E W KE+GP++ + G L VS P+ V + V + Sbjct: 40 FGVIHEFQDYENPGLLKLGE-WTKEYGPIYGITEGVEKTLIVSNPEFVHE----VFVKQF 94 Query: 479 KSSYLKATHEPLFG-------RGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQ 637 + Y + T+ P+ G ++ + G W R + +P F K + +M + Sbjct: 95 DNFYGRKTN-PIQGDPNKNKRAHLVSAQGHRWKRLRTLSSPTF---SNKNLRKIMSTVEE 150 Query: 638 TLLEPWEARVDKSGGTVDIKIDDDIRAYSADVISRTCFGSS---------YVKGKKIFLK 790 T++E D S + + D + ++ D+I R G + K K IF Sbjct: 151 TVVELMRHLDDASAKGKAVDLLDYYQEFTLDIIGRIAMGQTESLMFRNPMLPKVKGIFKD 210 Query: 791 LRELQKAVSKPNVLAEMTGLRFFPTKKNRQ-AWGLHKQVHRLILEIVKE----------- 934 R+L VS +A FF + Q A+ + V + + + +++ Sbjct: 211 GRKLPFLVSGIFPIAGTMFREFFMRFPSIQPAFDIMSTVEKALNKRLEQRAADEKAGIEP 270 Query: 935 SGEDKNLLRAILHSASS-----SKVGLGEAENFIVDNCKSIYF------------AGYES 1063 SGE ++ + L + ++ + LG A+ I K + F AGY++ Sbjct: 271 SGEPQDFIDLFLDARANVDFFEEESALGFAKTEIAKVDKQLTFDEIIGQLFVFLLAGYDT 330 Query: 1064 TAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGRPLDSQSLQKMKNLTMVIQETLRLYPAG 1243 TA++ ++ LL HPE Q ++++EV C + + K+K + V++E LR+YP Sbjct: 331 TALSLSYSSYLLARHPEIQKKLQEEVDRECPNPEVTFDQISKLKYMECVVKEALRMYPLA 390 Query: 1244 AFV-SRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARFSDARPQLHS 1420 + V +R ++E + GV I KG N+ + T+H DPK+WG DA EF P R+ ++ Sbjct: 391 SIVHNRKCMKETNVLGVQIEKGTNVQVDTWTLHYDPKVWGEDANEFRPERWESGDELFYA 450 Query: 1421 ---YLPFGAGARTCLGQGFATAE 1480 YLPFG G R C+G A E Sbjct: 451 KGGYLPFGMGPRICIGMRLAMME 473
>Q6NT55:CP4FN_HUMAN Cytochrome P450 4F22 - Homo sapiens (Human)| Length = 531 Score = 132 bits (333), Expect = 4e-30 Identities = 109/431 (25%), Positives = 186/431 (43%), Gaps = 34/431 (7%) Frame = +2 Query: 398 MGNVV-FLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRGILKSNGEAWAHQRKII 574 MG V+ L + PD ++ + + K +P G G+L S G+ W+ R+++ Sbjct: 100 MGPVLPLLVLVHPDYIKPLLGASAAIAPKDDLFYGFLKPWLGDGLLLSKGDKWSRHRRLL 159 Query: 575 APEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAYSADVISRTCFG 754 P F D +K + + SA + W + G V + + + I + D + + F Sbjct: 160 TPAFHFDILKPYMKIFNQSADIMHAKWRHLAE--GSAVSLDMFEHISLMTLDSLQKCVFS 217 Query: 755 ---------SSYVKGKKIFLKLRELQKAVSKPNVLAEMTGLRFFPTKKNRQAWGLHKQVH 907 S Y+ ++L L +V + L ++ + R+ VH Sbjct: 218 YNSNCQEKMSDYISA---IIELSAL--SVRRQYRLHHYLDFIYYRSADGRRFRQACDMVH 272 Query: 908 RLILEIVKE-----------------SGEDKNLLRAILHSASSSKVGLGEAENFIVDNCK 1036 E+++E G+ + + +L + L + + I Sbjct: 273 HFTTEVIQERRRALRQQGAEAWLKAKQGKTLDFIDVLLLARDEDGKELSDED--IRAEAD 330 Query: 1037 SIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGRPLDS---QSLQKMKNLTM 1207 + F G+++T+ +W L L +PE+Q++ R+E+ EV GR L+ L ++ TM Sbjct: 331 TFMFEGHDTTSSGISWMLFNLAKYPEYQEKCREEIQEVMKGRELEELEWDDLTQLPFTTM 390 Query: 1208 VIQETLRLYPAGAFVSRMALQELKL-GGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNP 1384 I+E+LR YP VSR +++KL G IPKG+ + + H +P +W PD+K +NP Sbjct: 391 CIKESLRQYPPVTLVSRQCTEDIKLPDGRIIPKGIICLVSIYGTHHNPTVW-PDSKVYNP 449 Query: 1385 ARFSDARPQLHS---YLPFGAGARTCLGQGFATAEXXXXXXXXXXXFALRLSPLYQHSPA 1555 RF PQ S Y+PF AG R C+GQ FA AE F L + + Sbjct: 450 YRFDPDNPQQRSPLAYVPFSAGPRNCIGQSFAMAELRVVVALTLLRFRLSVDRTRKVRRK 509 Query: 1556 LKLIVEPEFGV 1588 +LI+ E G+ Sbjct: 510 PELILRTENGL 520
>O35728:CP4AE_MOUSE Cytochrome P450 4A14 precursor - Mus musculus (Mouse)| Length = 507 Score = 132 bits (333), Expect = 4e-30 Identities = 114/416 (27%), Positives = 185/416 (44%), Gaps = 38/416 (9%) Frame = +2 Query: 479 KSSYLKATHEPLFGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWE 658 K+S + P G G+L NG+ W R+++ P F D +K V +M DS +L+ WE Sbjct: 112 KASGIYQFFAPWIGYGLLLLNGKKWFQHRRMLTPAFHYDILKPYVKIMADSVNIMLDKWE 171 Query: 659 ARVDKSGGTVDIKIDDDIRAYSADVISRTCF---GSSYV-KGKKIFLKLRE--------- 799 ++D G ++I + + D + + F GS + + K++ K E Sbjct: 172 -KLD--GQDHPLEIFHCVSLMTLDTVMKCAFSYQGSVQLDENSKLYTKAVEDLNNLTFFR 228 Query: 800 LQKAVSKPNVLAEMTG---------------------LRFFPTKKNRQAWGLHKQVHRLI 916 L+ A K N++ M+ +R + + K+ H Sbjct: 229 LRNAFYKYNIIYNMSSDGRLSHHACQIAHEHTDGVIKMRKSQLQNEEELQKARKKRHLDF 288 Query: 917 LEIVKESG-EDKNLLRAILHSASSSKVGLGEAENFIVDNCKSIYFAGYESTAVTAAWCLM 1093 L+I+ + ED+N L S + E + F+ F G+++TA +W Sbjct: 289 LDILLFARMEDRNSL--------SDEDLRAEVDTFM--------FEGHDTTASGISWIFY 332 Query: 1094 LLGLHPEWQDRVRQEVLEVCG-GRPLDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQ 1270 L HPE Q R R+EV + G G + L +M TM I+E LRLYP VSR Sbjct: 333 ALATHPEHQQRCREEVQSILGDGTSVTWDHLGQMPYTTMCIKEALRLYPPVISVSRELSS 392 Query: 1271 ELKL-GGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARFS-DARPQLHSYLPFGAGA 1444 + G IPKG+ I + +H +P+ W P+ K F+P+RF+ D+ H+YLPF G+ Sbjct: 393 PVTFPDGRSIPKGITATISIYGLHHNPRFW-PNPKVFDPSRFAPDSSHHSHAYLPFSGGS 451 Query: 1445 RTCLGQGFATAEXXXXXXXXXXXFALRLSPLYQHSPALKLIVEPEFGVDITLTKVQ 1612 R C+G+ FA E F L P P +L+++ + G+ + L K++ Sbjct: 452 RNCIGKQFAMNELKVAVALTLLRFELLPDPTRIPVPIARLVLKSKNGIHLCLKKLR 507
>P10611:CP4A4_RABIT Cytochrome P450 4A4 precursor - Oryctolagus cuniculus (Rabbit)| Length = 510 Score = 132 bits (333), Expect = 4e-30 Identities = 117/451 (25%), Positives = 200/451 (44%), Gaps = 33/451 (7%) Frame = +2 Query: 356 EKW-RKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKS------SYLKATHEPL 514 +KW K G + GN L V PD ++ I LG+S +Y T P Sbjct: 76 QKWVEKFPGACPWWLSGNKARLLVYDPDYLKVI-------LGRSDPKAPRNYKLMT--PW 126 Query: 515 FGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDI 694 G G+L +G+ W R+++ P F D +K V LMVDS Q +L+ WE + + + Sbjct: 127 IGYGLLLLDGQTWFQHRRMLTPAFHYDILKPYVGLMVDSVQIMLDRWEQLISQDSS---L 183 Query: 695 KIDDDIRAYSADVISRTCFGSSYVKGKKIFLKLRELQKAVSKPNVLAEMTGLRFFPTKK- 871 +I + + D I + F SY ++ +A++ N L F Sbjct: 184 EIFQHVSLMTLDTIMKCAF--SYQGSVQLDRNSHSYIQAINDLNNLVFYRARNVFHQSDF 241 Query: 872 -----------NRQAWGLHKQVHRLILEI---VKESGEDKNLLR--------AILHSASS 985 +R H+ R+I + +++ GE + + R +L + Sbjct: 242 LYRLSPEGRLFHRACQLAHEHTDRVIQQRKAQLQQEGELEKVRRKRRLDFLDVLLFAKME 301 Query: 986 SKVGLGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCG-GR 1162 + L + + + + F G+++TA +W L HPE Q R R+E+ + G G Sbjct: 302 NGSSLSDQD--LRAEVDTFMFEGHDTTASGVSWIFYALATHPEHQHRCREEIQGLLGDGA 359 Query: 1163 PLDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKL-GGVHIPKGVNIYIPVSTMH 1339 + + L +M TM I+E LRLYP V+R + + G +PKGV +++ + +H Sbjct: 360 SITWEHLDQMPYTTMCIKEALRLYPPVPSVTRQLSKPVTFPDGRSLPKGVILFLSIYGLH 419 Query: 1340 LDPKLWGPDAKEFNPARFS-DARPQLHSYLPFGAGARTCLGQGFATAEXXXXXXXXXXXF 1516 +PK+W + + F+P RF+ D+ H++LPF GAR C+G+ FA E F Sbjct: 420 YNPKVW-QNPEVFDPFRFAPDSAYHSHAFLPFSGGARNCIGKQFAMRELKVAVALTLVRF 478 Query: 1517 ALRLSPLYQHSPALKLIVEPEFGVDITLTKV 1609 L P P +++++ + G+ + L K+ Sbjct: 479 ELLPDPTRIPIPIARVVLKSKNGIHLRLRKL 509
>P33268:CP3A8_MACFA Cytochrome P450 3A8 - Macaca fascicularis (Crab eating macaque)| (Cynomolgus monkey) Length = 503 Score = 132 bits (332), Expect = 5e-30 Identities = 119/453 (26%), Positives = 209/453 (46%), Gaps = 29/453 (6%) Frame = +2 Query: 200 FRRQGIGGPRPSFPYGNMADXXXXXXXXXXXXXXXXXXXIVHDYRPAVLPFYEKWRKEHG 379 F++ GI GP P GN+ YR F + K++G Sbjct: 33 FKKLGIPGPTPLPLLGNILS-----------------------YRKGFWTFDMECYKKYG 69 Query: 380 PVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGR-GILKS-----N 541 V+ + G L ++ P++++ + L K Y T+ FG G +K+ Sbjct: 70 KVWGFYDGRQPVLAITDPNMIKTV-------LVKECYSVFTNRRPFGPVGFMKNAISIAE 122 Query: 542 GEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAY 721 E W R +++P F K+K MV ++ L+ R ++G V +K D AY Sbjct: 123 DEEWKRIRSLLSPTFTSGKLKEMVPIIAKYGDVLVRNLR-REAETGKPVTLK--DVFGAY 179 Query: 722 SADVISRTCFGSS----------YVKGKKIFLKLRELQKAVSKPNV------LAEMTGLR 853 S DVI+ T FG + +V+ K L+ L + + E+ + Sbjct: 180 SMDVITSTSFGVNIDSLNNPQDPFVENTKKLLRFDFLDPFFLSITIFPFIIPILEVLNIS 239 Query: 854 FFPTKKNRQAWGLHKQVHRLILEIVKESGEDK-NLLRAILHSASSSKVGLGEAENFIVDN 1030 FP + L K V R+ +K++ + + + L+ ++ S +S + +A + + Sbjct: 240 IFPREVTSF---LRKSVKRIKESRLKDTQKHRVDFLQLMIDSQNSKETESHKALSDLELV 296 Query: 1031 CKSIYF--AGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGR-PLDSQSLQKMKNL 1201 +SI F AGYE+T+ ++ + L HP+ Q ++++E+ V + P ++ +M+ L Sbjct: 297 AQSIIFIFAGYETTSSVLSFIIYELATHPDVQQKLQEEIDTVLPNKAPPTYDTVLQMEYL 356 Query: 1202 TMVIQETLRLYPAGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFN 1381 MV+ ETLR++P + R+ +++++ G+ IPKGV + IP +H DPK W P+ ++F Sbjct: 357 DMVVNETLRIFPIAMRLERVCKKDVEINGIFIPKGVVVMIPSYALHHDPKYW-PEPEKFL 415 Query: 1382 PARFS---DARPQLHSYLPFGAGARTCLGQGFA 1471 P RFS + + Y PFG+G R C+G FA Sbjct: 416 PERFSKKNNDNIDPYIYTPFGSGPRNCIGMRFA 448
>O88833:CP4AA_MOUSE Cytochrome P450 4A10 - Mus musculus (Mouse)| Length = 509 Score = 132 bits (331), Expect = 6e-30 Identities = 106/394 (26%), Positives = 174/394 (44%), Gaps = 27/394 (6%) Frame = +2 Query: 509 PLFGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTV 688 P G G+L NG+ W R+++ P F D +K V M DS + +L+ WE D+ Sbjct: 124 PWIGYGLLLLNGQPWFQHRRMLTPAFHYDILKPYVKNMADSIRLMLDKWERLADQDSS-- 181 Query: 689 DIKIDDDIRAYSADVISRTCF---GSSYVKGKKIFLKLRELQKAVSKPNVLAEMTGLRFF 859 I+I I + D + + F GS V G R +A+ N L F Sbjct: 182 -IEIFQHISLMTLDTVMKCAFSHKGSVQVDGN-----YRTYLQAIGDLNNLFHSRVRNIF 235 Query: 860 PTK----KNRQAWGLHKQVHRL-------ILEIVKESGEDKNLLRAILHSA--------- 979 K L KQ +L ++++ K+ +D+ L I Sbjct: 236 HQNDTIYKLSSNGRLAKQACQLAHDHTDGVIKLRKDQLQDEGELEKIKKKRRLDFLDILL 295 Query: 980 -SSSKVGLGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCG 1156 + + G ++ + + F G+++TA +W L HP+ Q R R+EV + G Sbjct: 296 FARMENGDSMSDKDLRAEVDTFMFEGHDTTASGVSWIFYALATHPDHQQRCREEVQSLLG 355 Query: 1157 -GRPLDSQSLQKMKNLTMVIQETLRLYP-AGAFVSRMALQELKLGGVHIPKGVNIYIPVS 1330 G + L ++ TM I+E LRLYP V ++ G +PKGV + + + Sbjct: 356 DGSSITWDHLDQIPYTTMCIKEALRLYPPVPGIVRELSTSVTFPDGRSLPKGVQVTLSIY 415 Query: 1331 TMHLDPKLWGPDAKEFNPARFSDARPQ-LHSYLPFGAGARTCLGQGFATAEXXXXXXXXX 1507 +H +PK+W P+ + F+P+RF+ P+ HS+LPF GAR C+G+ FA +E Sbjct: 416 GLHHNPKVW-PNPEVFDPSRFAPDSPRHSHSFLPFSGGARNCIGKQFAMSELKVIVALTL 474 Query: 1508 XXFALRLSPLYQHSPALKLIVEPEFGVDITLTKV 1609 F L P P +L+++ + G+ + L K+ Sbjct: 475 LRFELLPDPTRVPMPLARLVLKSKNGIYLHLKKL 508
>P51538:CP3A9_RAT Cytochrome P450 3A9 - Rattus norvegicus (Rat)| Length = 503 Score = 131 bits (330), Expect = 8e-30 Identities = 117/413 (28%), Positives = 183/413 (44%), Gaps = 32/413 (7%) Frame = +2 Query: 329 YRPAVLPFYEKWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHE 508 YR F + K++G ++ G L ++ PD+++ + L K Y T+ Sbjct: 53 YRKGFWEFDKYCHKKYGKLWGLYDGRQPVLAITDPDIIKTV-------LVKECYSTFTNR 105 Query: 509 PLFGR-GILK-----SNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVD 670 FG GILK S E W R +++P F K+K M ++ L+ + Sbjct: 106 RNFGPVGILKKAISISEDEEWKRIRALLSPTFTSGKLKEMFPIINQYTDMLVRNMRQGSE 165 Query: 671 KSGGTVDIKIDDDIRAYSADVISRTCFGSS----------YVKGKKIFLKLRELQKAVSK 820 + T + D AYS DVI+ T FG + +V+ K LK Sbjct: 166 EGKPT---SMKDIFGAYSMDVITATSFGVNVDSLNNPQDPFVEKVKKLLKFDIFDPLFLS 222 Query: 821 PNV------LAEMTGLRFFPTKKNRQAWGLHK-QVHRLILEIVKESGEDKNLLRAILHSA 979 + L E + FP R K V R+ +KE + + ++ ++ Sbjct: 223 VTLFPFLTPLFEALNVSMFP----RDVIDFFKTSVERMKENRMKEKEKQRMDFLQLMINS 278 Query: 980 SSSKV-----GLGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVL 1144 +SKV L + E IV FAGYE+T+ ++ L LL +HP+ Q +++ E+ Sbjct: 279 QNSKVKDSHKALSDVE--IVAQSVIFIFAGYETTSSALSFVLYLLAIHPDIQKKLQDEID 336 Query: 1145 EVCGGRPLDS-QSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKLGGVHIPKGVNIYI 1321 + + +L +M+ L MV+ ETLRLYP + R+ ++++ GV IPKG + I Sbjct: 337 AALPNKAHATYDTLLQMEYLDMVVNETLRLYPIAGRLERVCKTDVEINGVFIPKGTVVMI 396 Query: 1322 PVSTMHLDPKLWGPDAKEFNPARFSDARP---QLHSYLPFGAGARTCLGQGFA 1471 P +H DP W P+ +EF P RFS + YLPFG G R C+G FA Sbjct: 397 PTFALHKDPHYW-PEPEEFRPERFSKKNQDNINPYMYLPFGNGPRNCIGMRFA 448
>Q8SPK1:CP4AO_PIG Cytochrome P450 4A24 - Sus scrofa (Pig)| Length = 504 Score = 130 bits (327), Expect(2) = 9e-30 Identities = 106/390 (27%), Positives = 180/390 (46%), Gaps = 23/390 (5%) Frame = +2 Query: 509 PLFGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTV 688 P G G+L NG+ W +R+++ P F D +K V LM S Q +L+ WE V + Sbjct: 119 PWIGCGLLLLNGQTWFQRRRMLTPAFHYDILKPYVGLMAKSVQVMLDKWEQLVAQD---P 175 Query: 689 DIKIDDDIRAYSADVISRTCF---GSSYVKGK-----KIFLKLRELQKAVSKPNVLAEMT 844 ++I + + D I + F GS+ G + L+ L +K L Sbjct: 176 RLEIVGPVSLMTLDTIMKCAFSHQGSAQTDGDSHSYIQAIWDLKNLFSIRTKSAFLQNDI 235 Query: 845 GLRFFP--TKKNRQAWGLHKQVHRLI---LEIVKESGEDKNLLRA-------ILHSASSS 988 R P K +R A H+ R+I +++ GE +N+ + IL A Sbjct: 236 IYRLSPEGRKNHRAARIAHQHTDRVIQLRKAQLQKQGEMENVRKKRHLDFLDILLLARME 295 Query: 989 KVGLGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCG-GRP 1165 K G ++ + + F G+++TA +W L L HPE Q R R+E+ + G G Sbjct: 296 K-GNSLSDTDLRAEVDTFMFEGHDTTASGISWILYALASHPEHQQRCREEIQGLLGDGTS 354 Query: 1166 LDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKL-GGVHIPKGVNIYIPVSTMHL 1342 + L +M TM I+E LRLYP VSR + + G +P G+ + + + +H Sbjct: 355 ITWDHLDQMPYTTMCIKEALRLYPPVPGVSRELSKPITFPDGRSLPAGITLSLSIYGLHH 414 Query: 1343 DPKLWGPDAKEFNPARFSDARPQ-LHSYLPFGAGARTCLGQGFATAEXXXXXXXXXXXFA 1519 +P++W P+ +EF+P+RF+ + H+++PF G+R C+G+ FA E F Sbjct: 415 NPQVW-PNPEEFDPSRFAPGSARHSHAFMPFSGGSRNCIGKQFAMNEMKVAVALTLLRFE 473 Query: 1520 LRLSPLYQHSPALKLIVEPEFGVDITLTKV 1609 L P + ++++ + G+ + L K+ Sbjct: 474 LAPDPSRKPIATPEVVLNSKNGIHLKLRKL 503 Score = 21.9 bits (45), Expect(2) = 9e-30 Identities = 9/20 (45%), Positives = 11/20 (55%) Frame = +3 Query: 348 PSTRNGEKSMVQCSLTRWGT 407 P + EK C+L RWGT Sbjct: 68 PLLKRVEKYPSACALWRWGT 87
>Q8SPK0:CP4AP_PIG Cytochrome P450 4A25 - Sus scrofa (Pig)| Length = 504 Score = 131 bits (329), Expect = 1e-29 Identities = 107/390 (27%), Positives = 182/390 (46%), Gaps = 23/390 (5%) Frame = +2 Query: 509 PLFGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTV 688 P G G+L NG+ W +R+++ P F D +K V LM S Q +L+ WE V + Sbjct: 119 PWIGCGLLLLNGQTWFQRRRMLTPAFHYDILKPYVGLMAKSVQVMLDKWEQLVAQD---P 175 Query: 689 DIKIDDDIRAYSADVISRTCF---GSSYVKGK-----KIFLKLRELQKAVSKPNVLAEMT 844 ++I + + D I + F GS+ G + L+ L +K L Sbjct: 176 RLEIVGPVSLMTLDTIMKCAFSHQGSAQTDGDSHSYIQAIWDLKNLFSIRTKSAFLQNDI 235 Query: 845 GLRFFP--TKKNRQAWGLHKQVHRLI---LEIVKESGEDKNLLRA-------ILHSASSS 988 R P K +R A H+ R+I +++ GE +N+ + IL A Sbjct: 236 IYRLSPEGRKNHRAARIAHQHTDRVIQLRKAQLQKQGEMENVRKKRHLDFLDILLLARME 295 Query: 989 KVGLGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCG-GRP 1165 K G ++ + + F G+++TA +W L L HPE Q R R+E+ + G G Sbjct: 296 K-GNSLSDTDLRAEVDTFMFEGHDTTASGISWILYALASHPEHQQRCREEIQGLLGDGTS 354 Query: 1166 LDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKL-GGVHIPKGVNIYIPVSTMHL 1342 + L +M TM I+E LRLYP VSR + + G +P G+ + + V ++H Sbjct: 355 ITWDHLDQMPYTTMCIKEALRLYPPVPGVSRELSKPITFPDGRSLPAGIILSLSVYSLHH 414 Query: 1343 DPKLWGPDAKEFNPARFSDARPQ-LHSYLPFGAGARTCLGQGFATAEXXXXXXXXXXXFA 1519 +P++W P+ +EF+P+RF+ + H+++PF G+R C+G+ FA E F Sbjct: 415 NPQVW-PNPEEFDPSRFAPGSARHSHAFMPFSGGSRNCIGKQFAMNEMKVAVALTLLRFE 473 Query: 1520 LRLSPLYQHSPALKLIVEPEFGVDITLTKV 1609 L P + + ++++ + G+ + L K+ Sbjct: 474 LAPDPSRKPTVIPEVVLHSKNGIHLKLRKL 503
>O70537:CP3AV_MESAU Cytochrome P450 3A31 - Mesocricetus auratus (Golden hamster)| Length = 501 Score = 131 bits (329), Expect = 1e-29 Identities = 121/450 (26%), Positives = 202/450 (44%), Gaps = 26/450 (5%) Frame = +2 Query: 200 FRRQGIGGPRPSFPYGNMADXXXXXXXXXXXXXXXXXXXIVHDYRPAVLPFYEKWRKEHG 379 F++QGI GP+P GN V +Y + F + K++G Sbjct: 33 FKKQGIPGPKPLPFLGN-----------------------VLNYYKGIWTFDIECHKKYG 69 Query: 380 PVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFG------RGILKSN 541 ++ G V+ ++++++ L K Y T+ FG + + S Sbjct: 70 KIWGLFEGQRPLFTVTDTEMIKNV-------LVKECYSIFTNRRDFGPVGIMSKAVSISK 122 Query: 542 GEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAY 721 E W R +++P F K+K M ++ L++ +K G V K + AY Sbjct: 123 DEEWKRIRALLSPTFTSGKLKEMFPIIEQYGDILVKFLRREAEK-GNPVTTK--EVFGAY 179 Query: 722 SADVISRTCFG---SSYVKGKKIFLKLRELQKA-VSKPNVLAEMTGLRFFPTKKNRQAWG 889 S DVI+ T FG S K + K R+L + P L+ + P + Sbjct: 180 SMDVITSTAFGVSVDSLNNPKDLLWKGRKLLRFDFFDPLFLSVVLFPFLIPIYEKLNVSM 239 Query: 890 LHKQ---VHRLILEIVKESGEDKN------LLRAILHSASSSK---VGLGEAENFIVDNC 1033 K R ++ KE+ D N L+ +++S +SK L + E I+ Sbjct: 240 FPKDSISFFRKFVDKTKENRLDYNQKHRVDFLQLMMNSHDNSKDSHKALSDME--IIAQS 297 Query: 1034 KSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGRPLDS-QSLQKMKNLTMV 1210 FAGY++T+ T ++ L LL HP+ Q ++++E+ + S + +M+ L MV Sbjct: 298 IIFIFAGYDTTSSTLSFALYLLATHPDVQKKLQEEIDIALPNKARPSYDKVMEMEYLDMV 357 Query: 1211 IQETLRLYPAGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPAR 1390 + ETLRLYP G+ + R+ Q++++ GV +PKG + +PV +H DP+ W P+ ++F P R Sbjct: 358 LNETLRLYPIGSRLERVCKQDVEMDGVFVPKGSIVMVPVFALHYDPQYW-PEPEKFRPER 416 Query: 1391 FSDARP---QLHSYLPFGAGARTCLGQGFA 1471 FS + +LPFG G R C+G FA Sbjct: 417 FSKENKGSIDPYIFLPFGNGPRNCIGMRFA 446
>Q8N118:CP4X1_HUMAN Cytochrome P450 4X1 - Homo sapiens (Human)| Length = 509 Score = 130 bits (328), Expect = 1e-29 Identities = 105/404 (25%), Positives = 185/404 (45%), Gaps = 27/404 (6%) Frame = +2 Query: 479 KSSYLKATHEPLFGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWE 658 KS YL+ PL G+G+ +G W R+++ P F + +K +++M S + +L+ WE Sbjct: 109 KSQYLQKFSPPLLGKGLAALDGPKWFQHRRLLTPGFHFNILKAYIEVMAHSVKMMLDKWE 168 Query: 659 ARVDKSGGTVDIKIDDDIRAYSADVISRTCFGSS-----------YVK-----GKKIFLK 790 +V++ + I + S D+I + F Y K K IF + Sbjct: 169 KICSTQDTSVEVY--EHINSMSLDIIMKCAFSKETNCQTNSTHDPYAKAIFELSKIIFHR 226 Query: 791 LRELQKAVSKPNVLAEMT--GLRFFPTKK--NRQAWGLHKQVHRLILEIVKESGEDKNLL 958 L L + +++ +++ G RF + N+ + ++ + + VK+ K Sbjct: 227 LYSL---LYHSDIIFKLSPQGYRFQKLSRVLNQYTDTIIQERKKSLQAGVKQDNTPKRKY 283 Query: 959 RAILHSASSSK--VGLGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVR 1132 + L S+K G ++ + + AG+++ A + +W L L L+PE Q+R R Sbjct: 284 QDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAASISWILYCLALNPEHQERCR 343 Query: 1133 QEVLEVCG-GRPLDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKL-GGVHIPKG 1306 +EV + G G + L +M TM I+ET RL PA +SR + L G +P G Sbjct: 344 EEVRGILGDGSSITWDQLGEMSYTTMCIKETCRLIPAVPSISRDLSKPLTFPDGCTLPAG 403 Query: 1307 VNIYIPVSTMHLDPKLWGPDAKEFNPARFSDARPQL---HSYLPFGAGARTCLGQGFATA 1477 + + + + +H +P +W + K F+P RFS ++YLPF AG+R C+GQ FA Sbjct: 404 ITVVLSIWGLHHNPAVW-KNPKVFDPLRFSQENSDQRHPYAYLPFSAGSRNCIGQEFAMI 462 Query: 1478 EXXXXXXXXXXXFALRLSPLYQHSPALKLIVEPEFGVDITLTKV 1609 E F + P + I++P+ G+ + L K+ Sbjct: 463 ELKVTIALILLHFRVTPDPTRPLTFPNHFILKPKNGMYLHLKKL 506
>Q9VXY0:CP4S3_DROME Probable cytochrome P450 4s3 - Drosophila melanogaster (Fruit fly)| Length = 495 Score = 130 bits (328), Expect = 1e-29 Identities = 117/467 (25%), Positives = 207/467 (44%), Gaps = 38/467 (8%) Frame = +2 Query: 341 VLPFYEKWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATH----- 505 +L + ++ R++HGPVF G + + + P+ ++ + LG + L + Sbjct: 52 ILNWLKELREKHGPVFRIWFGKDLMVMFTDPEDIKQL-------LGNNQLLTKSRNYELL 104 Query: 506 EPLFGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGT 685 EP G+G+L + GE+W +RK++ P F + + M ++ + L+ R +G + Sbjct: 105 EPWLGKGLLTNGGESWHRRRKLLTPGFHFRILSEFKEPMEENCRILVR--RLRTKANGES 162 Query: 686 VDIKIDDDIRAYSADVISRTCFG----------SSYVKGKKIFLKLRELQKAV--SKPNV 829 DI I ++ D I T G S YV+ + ++ Q + NV Sbjct: 163 FDIY--PYITLFALDAICETAMGIKKHAQLQSDSEYVQAVQSICRVMHKQSFSFWQRLNV 220 Query: 830 LAEMTGLRFFPTKKNRQAWG-LHKQVHRLIL----EIVKESGEDKN-------------- 952 + T P K+ A LH + +R+I ++++E E K Sbjct: 221 FFKHTK----PGKEREAALKVLHDETNRVIRLRREQLIQERNEWKPEAEQDDVGAKRRLA 276 Query: 953 LLRAILHSASSSKVGLGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVR 1132 L +L + L + + I + + F G+++T+ A+ L LL +P+ Q R Sbjct: 277 FLDMLLLTQMEGGAELSDTD--IREEVDTFMFEGHDTTSSAIAFALSLLSKNPDVQQRAF 334 Query: 1133 QEVLEVCGGRPLDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKLGGVHIPKGVN 1312 +E E L+ + + M L VI+ETLR+YP+ F SR L++L++G + +PKG + Sbjct: 335 EEASE------LEGREKESMPYLEAVIKETLRIYPSVPFFSRKVLEDLEVGKLTVPKGAS 388 Query: 1313 IYIPVSTMHLDPKLWGPDAKEFNPARFSDARPQLH--SYLPFGAGARTCLGQGFATAEXX 1486 I + +H DPK + PD + F+P RF Q+H ++ F AG R C+GQ FA E Sbjct: 389 ISCLIYMLHRDPKNF-PDPERFDPDRFLVNEKQMHPFAFAAFSAGPRNCIGQKFAMLELK 447 Query: 1487 XXXXXXXXXFALRLSPLYQHSPALKLIVEPEFGVDITLTKVQTASTT 1627 + +Q P +L+ + G+ + + TT Sbjct: 448 TSLAMLLRSYRFLPDKDHQPKPLAELVTKSGNGIRLRILPRDENGTT 494
>P51871:CP4F6_RAT Cytochrome P450 4F6 - Rattus norvegicus (Rat)| Length = 537 Score = 130 bits (328), Expect = 1e-29 Identities = 106/395 (26%), Positives = 172/395 (43%), Gaps = 27/395 (6%) Frame = +2 Query: 377 GPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRGILKSNGEAWA 556 GPV+ L + P+V+ + + K L +P G G+L S GE W Sbjct: 93 GPVYP-------ILRLVHPNVIAPLLQASAAVAPKEMTLYGFLKPWLGDGLLMSAGEKWN 145 Query: 557 HQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAYSADVI 736 H R+++ P F D +K V + S T+ W+ K +D+ + I + D + Sbjct: 146 HHRRLLTPAFHFDILKSYVKIFNKSVNTMHAKWQRLTAKGSARLDMF--EHISLMTLDSL 203 Query: 737 SRTCFG---SSYVKGKKIFLKLRELQKAVSKPNVLAEM-TGLRFFPTKKNRQAWGLHKQV 904 + F + + + EL + K + ++ T R+ V Sbjct: 204 QKCIFSFDSNCQESNSEYIAAILELSSLIVKRQRQPFLYLDFLYYLTADGRRFRKACDVV 263 Query: 905 HRLILEIVKESGEDKNL--LRAILHSASSSKV--------------GLGEAENFIVDNCK 1036 H +++E N + L + + +K G G ++ I Sbjct: 264 HNFTDAVIRERRSTLNTQGVDEFLKARAKTKTLDFIDVLLLAKDEHGKGLSDVDIRAEAD 323 Query: 1037 SIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGR---PLDSQSLQKMKNLTM 1207 + F G+++TA +W L L HPE+Q+R RQEV E+ R ++ L ++ LTM Sbjct: 324 TFMFGGHDTTASALSWILYNLARHPEYQERCRQEVRELLRDREPEEIEWDDLAQLPFLTM 383 Query: 1208 VIQETLRLYPAGAFVSRMALQELKL-GGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNP 1384 I+E+LRL+P +SR Q++ L G IPKG I + +H +P +W PD + +NP Sbjct: 384 CIKESLRLHPPVLLISRCCSQDIVLPDGRVIPKGNICVISIFGVHHNPSVW-PDPEVYNP 442 Query: 1385 ARFSDARPQLHS---YLPFGAGARTCLGQGFATAE 1480 RF PQ S ++PF AG R C+GQ FA +E Sbjct: 443 FRFDPENPQKRSPLAFIPFSAGPRNCIGQTFAMSE 477
>Q5RCN6:CP4V2_PONPY Cytochrome P450 4V2 - Pongo pygmaeus (Orangutan)| Length = 525 Score = 130 bits (327), Expect = 2e-29 Identities = 112/411 (27%), Positives = 187/411 (45%), Gaps = 31/411 (7%) Frame = +2 Query: 341 VLPFYEKWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFG 520 ++ + E++R H P+ +G V + + + V ++ L S + KSS K EP G Sbjct: 77 IIEYTEEYR--HMPLLKLWVGPVPMVALYNAENV-EVILTSSRQIDKSSMYKFL-EPWLG 132 Query: 521 RGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKI 700 G+L S G W +RK++ P F ++ +D+M + A L++ E V++ I Sbjct: 133 LGLLTSTGNKWRSRRKMLTPTFHFTILEDFLDIMNEQANILVKKLEKHVNQEAFNCFFYI 192 Query: 701 DDDIRAYSADVISRTCFG----------SSYVKGKKIFLKLRELQKAVSKPNVLAEMTGL 850 + D+I T G S YV+ ++ + + + + P + ++ L Sbjct: 193 T----LCALDIICETAMGKNIGAQSNDDSEYVRA--VYRMSQMIFQRIKMPWLWLDLWYL 246 Query: 851 RFFPTKKNRQAWG-LHKQVHRLILEIVKESGED-------------KNLLRAILHSASSS 988 F ++ + LH + +I E E D KN RA L S Sbjct: 247 MFKEGWEHEKGLKILHTFTNNVIAERANEMNADEDCRGVGRGSAPSKNKRRAFLDLLLSV 306 Query: 989 KVGLGE--AENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCG-- 1156 G + I + + F G+++TA W L LLG +PE Q +V E+ +V G Sbjct: 307 TDDEGNRLSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGCNPEVQQKVDHELDDVFGKS 366 Query: 1157 GRPLDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKLGGVHIPKGVNIYIPVSTM 1336 RP + L+K++ L VI+ETLRL+P+ +R ++ ++ G + KG I + Sbjct: 367 DRPATVEDLKKLRYLECVIKETLRLFPSVPLFARSVSEDCEVAGYRVLKGTEAVIIPYAL 426 Query: 1337 HLDPKLWGPDAKEFNPARFSDARPQ---LHSYLPFGAGARTCLGQGFATAE 1480 H DP+ + P+ +EF P RF Q ++Y+PF AG R C+GQ FA E Sbjct: 427 HRDPRYF-PNPEEFQPERFFPENAQGRHPYAYVPFSAGPRNCIGQKFAVME 476
>Q64417:CP3AE_CAVPO Cytochrome P450 3A14 - Cavia porcellus (Guinea pig)| Length = 503 Score = 130 bits (327), Expect = 2e-29 Identities = 118/448 (26%), Positives = 198/448 (44%), Gaps = 24/448 (5%) Frame = +2 Query: 200 FRRQGIGGPRPSFPYGNMADXXXXXXXXXXXXXXXXXXXIVHDYRPAVLPFYEKWRKEHG 379 F++ GI GP+P +GN V YR + F + RK++G Sbjct: 33 FKKLGIPGPKPLPLFGN-----------------------VLSYRKGMWSFDIECRKKYG 69 Query: 380 PVFTYSMGNVVFLHVSRPDVVRDINL--CVSLDLGKSSYLKATHEPLFGRGILKSNGEAW 553 ++ G L ++ PD+++ + + C S+ + S + + + S E W Sbjct: 70 NMWGLYDGPQPVLAITEPDMIKAVLVKECYSVFTNRRSLVPVG---FMKKAVSLSEDEEW 126 Query: 554 AHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAYSADV 733 R ++P F K+K M ++ L++ +K G V +K + AYS D+ Sbjct: 127 KRIRTQLSPNFTSGKLKEMFPIIKQYGDVLVKNLRQEAEK-GKPVQLK--EIFGAYSMDI 183 Query: 734 ISRTCFGSSY-----------VKGKKIF---LKLRELQKAVSKPNV--LAEMTGLRFFPT 865 I T FG + K +K+F L V P + L EM + FP Sbjct: 184 IVATAFGVNVDSLNNPHDPFVSKARKLFRFDFLSPFLLSIVMFPFLTQLYEMLSISIFPR 243 Query: 866 KKNRQAWGLHKQVHRLILEIVKESGEDKNLLRAILHSASSSKVGLGEAENFIVDNCKSIY 1045 + K+ LE K+ D L+ +L+S + +A + + +SI Sbjct: 244 DSLKFFTKFVKKTKENHLESNKKQRVD--FLQMMLNSQNFKDTESHKALSDVEILAQSII 301 Query: 1046 F--AGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGRPLDSQS-LQKMKNLTMVIQ 1216 F AGYE+T+ T ++ + L HP+ Q +++QE+ + + + + +M+ L MV+ Sbjct: 302 FIFAGYETTSSTLSFIMYSLATHPDVQKKLQQEIDKTLPNKAFPTYDVMMEMEYLDMVVN 361 Query: 1217 ETLRLYPAGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARFS 1396 ETLRLYP + RM+ ++ ++ G+ PKG + IP +H D K W P+ EF P RFS Sbjct: 362 ETLRLYPVTNRIERMSKKDFEINGMSFPKGTGVMIPSFALHRDSKYW-PEPDEFRPERFS 420 Query: 1397 DARPQ---LHSYLPFGAGARTCLGQGFA 1471 + + Y+PFG G R C+G A Sbjct: 421 KKNKENIDPYIYMPFGNGPRNCIGMRMA 448
>P08684:CP3A4_HUMAN Cytochrome P450 3A4 - Homo sapiens (Human)| Length = 503 Score = 130 bits (327), Expect = 2e-29 Identities = 120/453 (26%), Positives = 206/453 (45%), Gaps = 29/453 (6%) Frame = +2 Query: 200 FRRQGIGGPRPSFPYGNMADXXXXXXXXXXXXXXXXXXXIVHDYRPAVLPFYEKWRKEHG 379 F++ GI GP P GN+ Y F + K++G Sbjct: 33 FKKLGIPGPTPLPFLGNILS-----------------------YHKGFCMFDMECHKKYG 69 Query: 380 PVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGR-GILKS-----N 541 V+ + G L ++ PD+++ + L K Y T+ FG G +KS Sbjct: 70 KVWGFYDGQQPVLAITDPDMIKTV-------LVKECYSVFTNRRPFGPVGFMKSAISIAE 122 Query: 542 GEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAY 721 E W R +++P F K+K MV ++ L+ R ++G V +K D AY Sbjct: 123 DEEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLR-REAETGKPVTLK--DVFGAY 179 Query: 722 SADVISRTCFGSS----------YVKGKKIFLKLRELQKAVSKPNV------LAEMTGLR 853 S DVI+ T FG + +V+ K L+ L V + E+ + Sbjct: 180 SMDVITSTSFGVNIDSLNNPQDPFVENTKKLLRFDFLDPFFLSITVFPFLIPILEVLNIC 239 Query: 854 FFPTKKNRQAWGLHKQVHRLILEIVKESGEDK-NLLRAILHSASSSKVGLGEAENFIVDN 1030 FP + L K V R+ ++++ + + + L+ ++ S +S + +A + + Sbjct: 240 VFPREVTNF---LRKSVKRMKESRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDLELV 296 Query: 1031 CKSIYF--AGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGR-PLDSQSLQKMKNL 1201 +SI F AGYE+T+ ++ + L HP+ Q ++++E+ V + P ++ +M+ L Sbjct: 297 AQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYL 356 Query: 1202 TMVIQETLRLYPAGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFN 1381 MV+ ETLRL+P + R+ +++++ G+ IPKGV + IP +H DPK W + ++F Sbjct: 357 DMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYW-TEPEKFL 415 Query: 1382 PARFSDARP---QLHSYLPFGAGARTCLGQGFA 1471 P RFS + Y PFG+G R C+G FA Sbjct: 416 PERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFA 448
>Q6ZWL3:CP4V2_HUMAN Cytochrome P450 4V2 - Homo sapiens (Human)| Length = 525 Score = 129 bits (325), Expect = 3e-29 Identities = 111/411 (27%), Positives = 188/411 (45%), Gaps = 31/411 (7%) Frame = +2 Query: 341 VLPFYEKWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFG 520 ++ + E++R H P+ +G V + + + V ++ L S + KSS K EP G Sbjct: 77 IIEYTEEYR--HMPLLKLWVGPVPMVALYNAENV-EVILTSSKQIDKSSMYKFL-EPWLG 132 Query: 521 RGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKI 700 G+L S G W +RK++ P F ++ +D+M + A L++ E +++ I Sbjct: 133 LGLLTSTGNKWRSRRKMLTPTFHFTILEDFLDIMNEQANILVKKLEKHINQEAFNCFFYI 192 Query: 701 DDDIRAYSADVISRTCFG----------SSYVKGKKIFLKLRELQKAVSKPNVLAEMTGL 850 + D+I T G S YV+ ++ + + + P + ++ L Sbjct: 193 T----LCALDIICETAMGKNIGAQSNDDSEYVRA--VYRMSEMIFRRIKMPWLWLDLWYL 246 Query: 851 RFFPTKKNRQAWG-LHKQVHRLILEIVKE-------------SGEDKNLLRAILHSASSS 988 F +++++ LH + +I E E S KN RA L S Sbjct: 247 MFKEGWEHKKSLKILHTFTNSVIAERANEMNANEDCRGDGRGSAPSKNKRRAFLDLLLSV 306 Query: 989 KVGLGE--AENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCG-- 1156 G + I + + F G+++TA W L LLG +PE Q +V E+ +V G Sbjct: 307 TDDEGNRLSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPEVQKKVDHELDDVFGKS 366 Query: 1157 GRPLDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKLGGVHIPKGVNIYIPVSTM 1336 RP + L+K++ L VI+ETLRL+P+ +R ++ ++ G + KG I + Sbjct: 367 DRPATVEDLKKLRYLECVIKETLRLFPSVPLFARSVSEDCEVAGYRVLKGTEAVIIPYAL 426 Query: 1337 HLDPKLWGPDAKEFNPARFSDARPQ---LHSYLPFGAGARTCLGQGFATAE 1480 H DP+ + P+ +EF P RF Q ++Y+PF AG R C+GQ FA E Sbjct: 427 HRDPRYF-PNPEEFQPERFFPENAQGRHPYAYVPFSAGPRNCIGQKFAVME 476
>Q02928:CP4AB_HUMAN Cytochrome P450 4A11 precursor - Homo sapiens (Human)| Length = 519 Score = 129 bits (325), Expect = 3e-29 Identities = 100/390 (25%), Positives = 178/390 (45%), Gaps = 23/390 (5%) Frame = +2 Query: 509 PLFGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTV 688 P G G+L NG+ W R+++ P F D +K V LM DS + +L+ WE + G Sbjct: 125 PWIGYGLLLLNGQTWFQHRRMLTPAFHYDILKPYVGLMADSVRVMLDKWEELL---GQDS 181 Query: 689 DIKIDDDIRAYSADVISRTCFG-----------SSYVKGKKIF--LKLRELQKAVSKPNV 829 +++ + + D I + F SY++ L ++ A + + Sbjct: 182 PLEVFQHVSLMTLDTIMKCAFSHQGSIQVDRNSQSYIQAISDLNNLVFSRVRNAFHQNDT 241 Query: 830 LAEMTGLRFFPTKKNRQAWGLHKQVHRLILEIVKESGEDKNLLRAILHSASSSKVGLGEA 1009 + +T + + + A QV +L +++ GE + + R H + L + Sbjct: 242 IYSLTSAGRWTHRACQLAHQHTDQVIQLRKAQLQKEGELEKIKRK-RHLDFLDILLLAKM 300 Query: 1010 ENFIVDNCKSI-------YFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCG-GRP 1165 EN + + K + F G+++TA +W L L HP+ Q+R R+E+ + G G Sbjct: 301 ENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLLGDGAS 360 Query: 1166 LDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKL-GGVHIPKGVNIYIPVSTMHL 1342 + L +M TM I+E LRLYP + R + G +PKG+ + + + +H Sbjct: 361 ITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLSIYGLHH 420 Query: 1343 DPKLWGPDAKEFNPARFSDARPQ-LHSYLPFGAGARTCLGQGFATAEXXXXXXXXXXXFA 1519 +PK+W P+ + F+P RF+ Q H++LPF G+R C+G+ FA E F Sbjct: 421 NPKVW-PNPEVFDPFRFAPGSAQHSHAFLPFSGGSRNCIGKQFAMNELKVATALTLLRFE 479 Query: 1520 LRLSPLYQHSPALKLIVEPEFGVDITLTKV 1609 L P P +L+++ + G+ + L ++ Sbjct: 480 LLPDPTRIPIPIARLVLKSKNGIHLRLRRL 509
>Q9PVE8:C330_FUNHE Cytochrome P450 3A30 - Fundulus heteroclitus (Killifish) (Mummichog)| Length = 496 Score = 129 bits (325), Expect = 3e-29 Identities = 124/482 (25%), Positives = 213/482 (44%), Gaps = 39/482 (8%) Frame = +2 Query: 143 LALYLYYTVWVVPQRLLAGFRRQGIGGPRPSFPYGNMADXXXXXXXXXXXXXXXXXXXIV 322 + L L Y W F+R GI GP+P +G M Sbjct: 18 VTLLLVYAYWPY-----GTFKRLGISGPKPVPFFGTMLH--------------------- 51 Query: 323 HDYRPAVLPFYEKWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINL--CVSLDLGKSSYLK 496 YR F E+ +K++G V+ G L V+ P++++ + + C+S + ++ Sbjct: 52 --YRRGFFTFDEECKKKYGKVWGIYDGRQPVLCVTDPEIIKAVLVKECLSFFTNRRNF-- 107 Query: 497 ATHEPLFGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKS 676 + PL+ + + + W R +++P F ++K M ++M + + L+ + + DK Sbjct: 108 RLNGPLYD-AVSIAEDDQWKRIRSVLSPSFTSGRLKEMFEIMKNHSANLIRSMKKKADKD 166 Query: 677 GGTVDIKIDDDIRAYSADVISRTCFG----------SSYVKGKKIFLK---LRELQKAVS 817 +D+K + +YS DV++ T F +V K LK L L AV+ Sbjct: 167 E-PLDLK--EFFGSYSMDVVTSTAFSVDIDSLNNPSDPFVTNIKKMLKFDFLNPLFLAVA 223 Query: 818 KPNVLA---EMTGLRFFPT-------------KKNRQAWGLHKQVH--RLILEIVKESG- 940 L E L FFP K NR+A +V +L+++ K SG Sbjct: 224 FFPFLGPILEKFELSFFPKSVTDFFYASLEKIKSNREASQQKSRVDFLQLMIDSQKNSGA 283 Query: 941 -EDKNLLRAILHSASSSKVGLGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEW 1117 +DK+L ++ I+ FAGYE+++ + + L +PE Sbjct: 284 QQDKSL-----------------TDHEILSQSMIFIFAGYETSSSSLTFLAYNLATNPEV 326 Query: 1118 QDRVRQEVLEVCGGR-PLDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKLGGVH 1294 ++++E+ + P+ Q L +M+ L VI E+LRL+P A + R+A +++ GV Sbjct: 327 MKKLQEEIDATFPNKAPVHYQPLMEMEYLDCVINESLRLFPIAARLERVAKAAVEINGVV 386 Query: 1295 IPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARFSDARP---QLHSYLPFGAGARTCLGQG 1465 IPK + + IP +H DP++W P+ + F P RFS + Y+PFG+G R C+G Sbjct: 387 IPKDMVVMIPTWPLHRDPEIW-PEPEAFKPERFSKKNKDNIDPYIYMPFGSGPRNCIGMR 445 Query: 1466 FA 1471 FA Sbjct: 446 FA 447
>P20816:CP4A2_RAT Cytochrome P450 4A2 precursor - Rattus norvegicus (Rat)| Length = 504 Score = 129 bits (324), Expect = 4e-29 Identities = 108/399 (27%), Positives = 176/399 (44%), Gaps = 31/399 (7%) Frame = +2 Query: 509 PLFGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTV 688 P G G+L NG+ W R+++ P F D +K V +M DS +L+ WE D+ Sbjct: 119 PWIGYGLLLLNGKKWFQHRRMLTPAFHYDILKPYVKIMADSVSIMLDKWEKLDDQDH--- 175 Query: 689 DIKIDDDIRAYSADVISRTCFGSSYVKGKKIFLKLRELQKAVSKPNVLAEMTGLRFFPTK 868 ++I + + D + + F S+ ++ + R KAV ++ L FF + Sbjct: 176 PLEIFHYVSLMTLDTVMKCAF--SHQGSVQLDVNSRSYTKAVE------DLNNLIFFRVR 227 Query: 869 K-----------------NRQAWGL-HKQVHRLILEIVKESGEDKNLLRA---------- 964 +R+A + H+ +I + ++ L +A Sbjct: 228 SAFYGNSIIYNMSSDGRLSRRACQIAHEHTDGVIKTRKAQLQNEEELQKARKKRHLDFLD 287 Query: 965 ILHSASSSKVGLGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVL 1144 IL A G ++ + + F G+++TA +W L HPE Q+R R+EV Sbjct: 288 ILLFAKMED-GKSLSDEDLRAEVDTFMFEGHDTTASGISWVFYALATHPEHQERCREEVQ 346 Query: 1145 EVCG-GRPLDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKL-GGVHIPKGVNIY 1318 + G G + L +M TM I+E LRLY VSR + G IPKG+ + Sbjct: 347 SILGDGTSVTWDHLDQMPYTTMCIKEALRLYSPVPSVSRELSSPVTFPDGRSIPKGIRVT 406 Query: 1319 IPVSTMHLDPKLWGPDAKEFNPARFSDARPQ-LHSYLPFGAGARTCLGQGFATAEXXXXX 1495 I + +H +P W P+ K F+P+RFS P+ H+YLPF GAR C+G+ FA E Sbjct: 407 ILIYGLHHNPSYW-PNPKVFDPSRFSPDSPRHSHAYLPFSGGARNCIGKQFAMNELKVAV 465 Query: 1496 XXXXXXFALRLSPLYQHSPALKLIVEPEFGVDITLTKVQ 1612 F L P P +L+++ + G+ + L K++ Sbjct: 466 ALTLLRFELLPDPTRIPVPMPRLVLKSKNGIHLRLKKLR 504
>Q64148:CP3AA_MESAU Cytochrome P450 3A10 - Mesocricetus auratus (Golden hamster)| Length = 503 Score = 129 bits (324), Expect = 4e-29 Identities = 124/494 (25%), Positives = 214/494 (43%), Gaps = 34/494 (6%) Frame = +2 Query: 200 FRRQGIGGPRPSFPYGNMADXXXXXXXXXXXXXXXXXXXIVHDYRPAVLPFYEKWRKEHG 379 F++ GI GP+P +G + Y F E K++G Sbjct: 33 FKKLGIPGPKPLPFFGTILG-----------------------YHDGTWKFDETCYKKYG 69 Query: 380 PVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFG------RGILKSN 541 ++ + G V L ++ P++++ + L K Y T+ FG + I S Sbjct: 70 KIWGFYDGRVPVLAIADPEIIKTV-------LVKECYSNFTNRRSFGPVGFMKKSITISK 122 Query: 542 GEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAY 721 E W R +++P F K+K M ++ TL++ R ++ G V++K + + AY Sbjct: 123 DEEWKRLRTLLSPAFTSGKLKEMFPIIGQYGDTLVKNLR-REEEKGKPVNMK--EILGAY 179 Query: 722 SADVISRTCFGSS----------YVKGKKIFLKLRELQKAVSKPNVLAEMTG----LRF- 856 S DVI+ T FG + +V+ + LK + + +T LRF Sbjct: 180 SMDVITGTSFGVNVDSLNNPEDPFVQKARKILKFNFFDPFILSIILFPFLTTIYDLLRFS 239 Query: 857 -FPTKKNRQAWGLHKQVHRLILEIVKESGEDKNL--LRAILHSASS----SKVGLGEAEN 1015 FP RQ+ K+ + + S + + + ++++ +S S+ L + E Sbjct: 240 IFP----RQSTNFFKKFITTMKKNRLHSNQKTRMDFFQLMMNTQNSKGKESQKALSDLE- 294 Query: 1016 FIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGR-PLDSQSLQKM 1192 + FAGYEST+ + L L HP+ Q ++ E+ + P+ L M Sbjct: 295 -MAAQAIIFIFAGYESTSTSICLVLYELATHPDVQKKLHDEIDSALPNKAPVTYDVLMGM 353 Query: 1193 KNLTMVIQETLRLYPAGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWGPDAK 1372 + L MVI E LRLYP + R++ + +++ G+ IPKG+ + +P +H DP+ W P+ + Sbjct: 354 EYLDMVINEGLRLYPIANRLERISKKAVEINGLFIPKGITVMVPTYPLHRDPEYW-PEPE 412 Query: 1373 EFNPARFSDARP---QLHSYLPFGAGARTCLGQGFATAEXXXXXXXXXXXFALRLSPLYQ 1543 EF P RFS + Y+PFG G R C+G FA F L+ + Sbjct: 413 EFRPERFSKENKGSIDPYVYMPFGNGPRNCIGMRFALLSMKLAVVSVLQNFTLQTCEQTE 472 Query: 1544 H--SPALKLIVEPE 1579 + A ++I++PE Sbjct: 473 NHLKFARQIILQPE 486
>O09158:CP3AP_MOUSE Cytochrome P450 3A25 - Mus musculus (Mouse)| Length = 503 Score = 129 bits (323), Expect = 5e-29 Identities = 116/453 (25%), Positives = 207/453 (45%), Gaps = 32/453 (7%) Frame = +2 Query: 320 VHDYRPAVLPFYEKWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKA 499 + +Y + F E K++G ++ + G L + P++++ + L K Y Sbjct: 50 IFNYYDGMWKFDEDCYKKYGKIWGFYEGPQPILAIMDPEIIKIV-------LVKECYSVF 102 Query: 500 THEPLFG------RGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEA 661 T+ FG + I S E W R +++P F K+K M +M L+ Sbjct: 103 TNRRFFGPVGFMKKAITISEDEEWKRLRTLLSPTFTSGKLKEMFPIMRQYGDILVRNLR- 161 Query: 662 RVDKSGGTVDIKIDDDIRAYSADVISRTCFGSS----------YVKGKKIFLKLRE---- 799 R ++ G + +K D AYS DVI+ T FG + +V+ K LK + Sbjct: 162 REEEKGEPISMK--DIFGAYSMDVITGTSFGVNVDSLNNPQDPFVQKAKKILKFKIFDPF 219 Query: 800 LQKAVSKPNV--LAEMTGLRFFPTKKNRQAWGLHKQ-VHRLILEIVKESGEDK-NLLRAI 967 L + P + + EM FP R + K+ V R+ E + + +++ + L+ + Sbjct: 220 LLSIILFPFLTPIYEMLNFSIFP----RDSMNFFKKFVKRMKKERLASNQKNRVDFLQLM 275 Query: 968 LHSASS----SKVGLGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQ 1135 +++ +S S+ L + E + F GY++T+ + + + L HP+ Q +++ Sbjct: 276 MNTQNSKGQESQKALSDLE--MAAQAVIFIFGGYDATSTSISLIMYELATHPDVQKKLQD 333 Query: 1136 EVLEVCGGR-PLDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKLGGVHIPKGVN 1312 E+ + P+ +L M+ L MV+ E+LRLYP + R++ +++++ GV IPKG Sbjct: 334 EIDRTLPNKAPVTYDALMDMEYLDMVVNESLRLYPIAIRLERVSKKDVEINGVFIPKGTV 393 Query: 1313 IYIPVSTMHLDPKLWGPDAKEFNPARFSDARP---QLHSYLPFGAGARTCLGQGFATAEX 1483 + IP+ +H +P+ W P+ +EF P RFS + Y+PFG G R C+G FA Sbjct: 394 VMIPIYPLHRNPEYW-PEPQEFCPERFSKENKGNIDPYIYMPFGNGPRNCIGMRFALISI 452 Query: 1484 XXXXXXXXXXFALRLSPLYQHSPALKLIVEPEF 1582 F ++ P + LK+ EP F Sbjct: 453 KLAVIGVLQNFTVQ--PCEETQIPLKISREPIF 483
>Q8AXY5:C356_FUNHE Cytochrome P450 3A56 - Fundulus heteroclitus (Killifish) (Mummichog)| Length = 496 Score = 129 bits (323), Expect = 5e-29 Identities = 123/482 (25%), Positives = 213/482 (44%), Gaps = 39/482 (8%) Frame = +2 Query: 143 LALYLYYTVWVVPQRLLAGFRRQGIGGPRPSFPYGNMADXXXXXXXXXXXXXXXXXXXIV 322 + L L Y W F+R GI GP+P +G M Sbjct: 18 VTLLLIYAYWPY-----GTFKRLGISGPKPVPFFGTMLH--------------------- 51 Query: 323 HDYRPAVLPFYEKWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINL--CVSLDLGKSSYLK 496 YR F E+ +K++G V+ G L V+ P++++ + + C+S + ++ Sbjct: 52 --YRRGFFTFDEECKKKYGKVWGIYDGRQPVLCVTDPEIIKAVLVKECLSFFTNRRNF-- 107 Query: 497 ATHEPLFGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKS 676 + PL+ + + + W R +++P F ++K M ++M + + L+ + + DK Sbjct: 108 HLNGPLYD-ALSVAEDDQWKRIRSVLSPSFTSGRLKEMFEIMKNHSANLIRSMKKKADKD 166 Query: 677 GGTVDIKIDDDIRAYSADVISRTCFG----------SSYVKGKKIFLK---LRELQKAVS 817 +D+K + +YS DV++ T F +V K LK L L AV+ Sbjct: 167 E-PLDLK--EFFGSYSMDVVTSTAFSVDIDSLNNPSDPFVTNIKKMLKFDFLNPLFLAVA 223 Query: 818 KPNVLA---EMTGLRFFPT-------------KKNRQAWGLHKQVH--RLILEIVKESG- 940 L E L FFP K NR+A +V +L+++ K SG Sbjct: 224 FFPFLGPILEKFELSFFPKSVTDFFYASLEKIKSNREASQQKSRVDFLQLMIDSQKNSGA 283 Query: 941 -EDKNLLRAILHSASSSKVGLGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEW 1117 +DK+L ++ I+ FAGYE+++ + + L +PE Sbjct: 284 QQDKSL-----------------TDHEILSQSMIFIFAGYETSSSSLTFLAYNLATNPEV 326 Query: 1118 QDRVRQEVLEVCGGR-PLDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKLGGVH 1294 ++++E+ + P+ Q L +M+ L VI E+LRL+P A + R+A +++ G+ Sbjct: 327 MKKLQEEIDATFPNKAPVHYQPLMEMEYLDCVINESLRLFPIAARLERVAKAAVEINGIV 386 Query: 1295 IPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARFSDARP---QLHSYLPFGAGARTCLGQG 1465 IPK + + IP +H DP++W P+ + F P RFS + Y+PFG+G R C+G Sbjct: 387 IPKDMVVMIPTWPLHRDPEIW-PEPEAFKPERFSKKNKDNIDPYIYMPFGSGPRNCIGMR 445 Query: 1466 FA 1471 FA Sbjct: 446 FA 447
>P08516:CP4AA_RAT Cytochrome P450 4A10 - Rattus norvegicus (Rat)| Length = 509 Score = 128 bits (322), Expect = 7e-29 Identities = 120/434 (27%), Positives = 195/434 (44%), Gaps = 31/434 (7%) Frame = +2 Query: 401 GNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRGILKSNGEAWAHQRKIIAP 580 G+ +L V PD ++ I + K++ + P G G+L NG+ W R+++ P Sbjct: 91 GSKAYLIVYDPDYMKVI---LGRSDPKANGVYRLLAPWIGYGLLLLNGQPWFQHRRMLTP 147 Query: 581 EFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAYSADVISRTCF--- 751 F D +K V M DS + +L+ WE +G I+I I + D + + F Sbjct: 148 AFHYDILKPYVKNMADSIRLMLDKWE---QLAGQDSSIEIFQHISLMTLDTVMKCAFSHN 204 Query: 752 GSSYVKGK-KIFLK----LRELQKAVSKPNVLAEMTGLRFFPTKK---NRQAWGLHKQVH 907 GS V G K +++ L +L + + N+ + + F + NR H Sbjct: 205 GSVQVDGNYKSYIQAIGNLNDLFHSRVR-NIFHQNDTIYNFSSNGHLFNRACQLAHDHTD 263 Query: 908 RLI------------LEIVKESGE----DKNLLRAILHSASSSKVGL-GEAENFIVDNCK 1036 +I LE VK+ D LL + + S S L E + F+ Sbjct: 264 GVIKLRKDQLQNAGELEKVKKKRRLDFLDILLLARMENGDSLSDKDLRAEVDTFM----- 318 Query: 1037 SIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCG-GRPLDSQSLQKMKNLTMVI 1213 F G+++TA +W L HPE Q R R+EV V G G + L ++ TM I Sbjct: 319 ---FEGHDTTASGVSWIFYALATHPEHQQRCREEVQSVLGDGSSITWDHLDQIPYTTMCI 375 Query: 1214 QETLRLYP-AGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPAR 1390 +E LRLYP V ++ G +PKG+ + + + +H +PK+W P+ + F+P+R Sbjct: 376 KEALRLYPPVPGIVRELSTSVTFPDGRSLPKGIQVTLSIYGLHHNPKVW-PNPEVFDPSR 434 Query: 1391 FSDARPQ-LHSYLPFGAGARTCLGQGFATAEXXXXXXXXXXXFALRLSPLYQHSPALKLI 1567 F+ P+ HS+LPF GAR C+G+ FA +E F L P P +L+ Sbjct: 435 FAPDSPRHSHSFLPFSGGARNCIGKQFAMSEMKVIVALTLLRFELLPDPTKVPIPLPRLV 494 Query: 1568 VEPEFGVDITLTKV 1609 ++ + G+ + L K+ Sbjct: 495 LKSKNGIYLYLKKL 508
>Q9JMA7:CP341_MOUSE Cytochrome P450 3A41 - Mus musculus (Mouse)| Length = 504 Score = 128 bits (321), Expect = 9e-29 Identities = 122/464 (26%), Positives = 202/464 (43%), Gaps = 40/464 (8%) Frame = +2 Query: 200 FRRQGIGGPRPSFPYGNMADXXXXXXXXXXXXXXXXXXXIVHDYRPAVLPFYEKWRKEHG 379 F++QGI GP P P+ V +Y + F + +++G Sbjct: 33 FKKQGIPGPTP-LPF----------------------LGTVLNYYKGLWKFDMECYEKYG 69 Query: 380 PVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFG------RGILKSN 541 + G + ++ P++++++ L K + T+ FG + I S Sbjct: 70 KTWGLFDGQMPLFVITDPEMIKNV-------LVKECFSVFTNRREFGPVGIMSKAISISK 122 Query: 542 GEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAY 721 E W R +++P F K+K M ++ L++ +K G V +K D + AY Sbjct: 123 DEEWKRYRALLSPTFTSGKLKEMFPVIEQYGDILVKYLMQEAEK-GKPVTMK--DVLGAY 179 Query: 722 SADVISRTCFGSS----------YVKGKKIFLKLRELQKAVSKPNVLAEMT--------- 844 S DVI+ T FG + +V+ K L++ V + +T Sbjct: 180 SIDVITSTSFGVNVDSLNNPEDPFVEKAKGILRVDFFDPLVFSVVLFPFLTPVYEMLNIC 239 Query: 845 -----GLRFFPTKKNRQAWGL--HKQVHRL----ILEIVKESGEDKNLLRAILHSASSSK 991 + FF NR KQ HR+ ++ + +DK+ H A S Sbjct: 240 MFPKDSIEFFKKFVNRMKESRLDSKQKHRVDFLQLMMNAHNNSKDKDS-----HKALSDM 294 Query: 992 VGLGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGR-PL 1168 ++ FI FAGYE+T+ T ++ L L HP+ Q ++++E+ E + P Sbjct: 295 EITAQSIVFI--------FAGYETTSSTLSFTLYCLATHPDIQKKLQEEIDETLPNKAPP 346 Query: 1169 DSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDP 1348 ++ +M+ L MV+ ETLRLYP G + R ++++L GV+IPKG + IP +H DP Sbjct: 347 TYDTVMEMEYLDMVLNETLRLYPIGNRLERFCKKDVELNGVYIPKGSTVMIPSYALHHDP 406 Query: 1349 KLWGPDAKEFNPARFSDARP---QLHSYLPFGAGARTCLGQGFA 1471 + W P+ +EF P RFS + Y+PFG G R C+G FA Sbjct: 407 QHW-PEPEEFQPERFSKENKGSIDPYLYMPFGIGPRNCIGMRFA 449
>P20817:CP4AE_RAT Cytochrome P450 4A14 precursor - Rattus norvegicus (Rat)| Length = 507 Score = 127 bits (320), Expect = 1e-28 Identities = 107/399 (26%), Positives = 175/399 (43%), Gaps = 31/399 (7%) Frame = +2 Query: 509 PLFGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTV 688 P G G+L NG+ W R+++ P F +K V +M DS +L+ WE D+ Sbjct: 122 PWIGYGLLLLNGKKWFQHRRMLTPAFHYGILKPYVKIMADSVNIMLDKWEKLDDQDH--- 178 Query: 689 DIKIDDDIRAYSADVISRTCFGSSYVKGKKIFLKLRELQKAVSKPNVLAEMTGLRFFPTK 868 ++I + + D + + F S+ ++ + R KAV ++ L FF + Sbjct: 179 PLEIFHYVSLMTLDTVMKCAF--SHQGSVQLDVNSRSYTKAVE------DLNNLTFFRVR 230 Query: 869 K-----------------NRQAWGL-HKQVHRLILEIVKESGEDKNLLRA---------- 964 +R+A + H+ +I + ++ L +A Sbjct: 231 SAFYGNSIIYNMSSDGRLSRRACQIAHEHTDGVIKMRKAQLQNEEELQKARKKRHLDFLD 290 Query: 965 ILHSASSSKVGLGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVL 1144 IL A G ++ + + F G+++TA +W L HPE Q+R R+EV Sbjct: 291 ILLFAKMED-GKSLSDEDLRAEVDTFMFEGHDTTASGISWVFYALATHPEHQERCREEVQ 349 Query: 1145 EVCG-GRPLDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKL-GGVHIPKGVNIY 1318 + G G + L ++ TM I+E LRLYP VSR + G IPKG+ Sbjct: 350 SILGDGTSVTWDHLDQIPYTTMCIKEALRLYPPVPSVSRELSSPVTFPDGRSIPKGITTT 409 Query: 1319 IPVSTMHLDPKLWGPDAKEFNPARFSDARPQ-LHSYLPFGAGARTCLGQGFATAEXXXXX 1495 I + +H +P W P+ K F+P+RFS P+ H+YLPF GAR C+G+ FA E Sbjct: 410 ILIYGLHHNPSYW-PNPKVFDPSRFSPDSPRHSHAYLPFSGGARNCIGKQFAMNELKVAV 468 Query: 1496 XXXXXXFALRLSPLYQHSPALKLIVEPEFGVDITLTKVQ 1612 F L P P +L+++ + G+ + L K++ Sbjct: 469 ALTLLRFELLPDPTRIPVPMARLVLKSKNGIHLRLKKLR 507
>Q64459:CP3AB_MOUSE Cytochrome P450 3A11 - Mus musculus (Mouse)| Length = 504 Score = 127 bits (320), Expect = 1e-28 Identities = 123/457 (26%), Positives = 204/457 (44%), Gaps = 33/457 (7%) Frame = +2 Query: 200 FRRQGIGGPRPSFPYGNMADXXXXXXXXXXXXXXXXXXXIVHDYRPAVLPFYEKWRKEHG 379 F++QGI GP+P P+ V +Y + F + K++G Sbjct: 33 FKKQGIPGPKP-LPF----------------------LGTVLNYYKGLWKFDMECYKKYG 69 Query: 380 PVFTYSMGNVVFLHVSRPDVVRDINL--CVSLDLGKSSYLKATHEPLFGRGILKSNGEAW 553 + G L V+ P+ ++++ + C S+ + + + + I S + W Sbjct: 70 KTWGLFDGQTPLLAVTDPETIKNVLVKECFSVFTNRRDFGPVG---IMSKAISISKDDEW 126 Query: 554 AHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAYSADV 733 R +++P F K+K M ++ L++ + K G V +K D + AYS DV Sbjct: 127 KRYRALLSPTFTSGKLKEMFPVIEQYGDILVKYLRQKA-KKGKPVTMK--DVLGAYSMDV 183 Query: 734 ISRTCFGSS----------YVKGKKIFLKLRE----LQKAVSKPNV--LAEMTGLRFFP- 862 I+ T FG + +V+ K L+ L V P + + EM + FP Sbjct: 184 ITSTSFGVNVDSLNNPEDPFVEKAKKLLRFDFFDPLLFSVVLFPFLTPVYEMLNICMFPK 243 Query: 863 ---------TKKNRQAWGLHKQVHRL-ILEIVKESGEDKNLLRAILHSASSSKVGLGEAE 1012 + +++ KQ HR+ L+++ S N + H A S ++ Sbjct: 244 DSIEFFKKFVDRMKESRLDSKQKHRVDFLQLMMNS--HNNSKDKVSHKALSDMEITAQSI 301 Query: 1013 NFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGR-PLDSQSLQK 1189 FI FAGYE+T+ T ++ L L HP+ Q +++ E+ E + P ++ + Sbjct: 302 IFI--------FAGYETTSSTLSFTLHSLATHPDIQKKLQDEIDEALPNKAPPTYDTVME 353 Query: 1190 MKNLTMVIQETLRLYPAGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWGPDA 1369 M+ L MV+ ETLRLYP + R+ ++++L GV+IPKG + IP +H DP+ W + Sbjct: 354 MEYLDMVLNETLRLYPIANRLERVCKKDVELNGVYIPKGSTVMIPSYALHHDPQHWS-EP 412 Query: 1370 KEFNPARFSDARP---QLHSYLPFGAGARTCLGQGFA 1471 +EF P RFS + YLPFG G R CLG FA Sbjct: 413 EEFQPERFSKENKGSIDPYVYLPFGNGPRNCLGMRFA 449
>Q98T91:C340_ORYLA Cytochrome P450 3A40 - Oryzias latipes (Medaka fish) (Japanese| ricefish) Length = 502 Score = 127 bits (320), Expect = 1e-28 Identities = 116/471 (24%), Positives = 211/471 (44%), Gaps = 28/471 (5%) Frame = +2 Query: 143 LALYLYYTVWVVPQRLLAGFRRQGIGGPRPSFPYGNMADXXXXXXXXXXXXXXXXXXXIV 322 + L L Y W F+R GI GP+P +G M Sbjct: 19 ITLLLVYAYWPY-----GTFKRLGIPGPKPVPFFGTMLA--------------------- 52 Query: 323 HDYRPAVLPFYEKWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINL--CVSLDLGKSSYLK 496 YR F ++ RK++G + G L ++ P ++ + + C SL + ++ Sbjct: 53 --YRKGFFNFDDECRKKYGKTWGIYDGRQPVLCITDPATIKAVLVKECYSLFTNRRNF-- 108 Query: 497 ATHEPLFGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKS 676 + PL+ + + + W R +++P F ++K M D+M + L++ + +VDK Sbjct: 109 RLNGPLYD-AVSIAEDDQWKRIRSVLSPSFTSGRLKEMFDIMKHHSANLIQSMKKKVDKD 167 Query: 677 GGTVDIKIDDDIRAYSADVISRTCFG----------SSYVKGKKIFLK---LRELQKAVS 817 +++ + YS DV++ T F +V K LK L L AV+ Sbjct: 168 E---PLEMKEYFGPYSMDVVTSTAFSVDIDSLNNPSDPFVTNIKKMLKFDFLNPLFLAVA 224 Query: 818 KPNVLA---EMTGLRFFPTKKNRQAWGLHKQVHRLILEIVKESGEDKN---LLRAILHSA 979 L E FP+ + +++ + E+ + K+ L+ ++ S Sbjct: 225 FFPFLGPILEKFEFSLFPSSVMDFFFAALRKI-----KANHENNKQKSRIDFLQLMIDSQ 279 Query: 980 SSSKVGL---GEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEV 1150 +++ GL G +++ I+ FAGYE+T+ + + L +PE ++++E+ Sbjct: 280 KNNQNGLQDKGLSDHEILSQAMIFIFAGYETTSSSLTFLAYNLATNPEVMKKLQKEIDAT 339 Query: 1151 CGGR-PLDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKLGGVHIPKGVNIYIPV 1327 + P+ L +M+ L V+ E+LRLYP A + R+A +++ G+ IPK + + +P Sbjct: 340 FPNKAPVQYVPLMEMEYLDCVVNESLRLYPIAARLERVAKATVEVNGLVIPKDMVVMVPT 399 Query: 1328 STMHLDPKLWGPDAKEFNPARFSDARPQL---HSYLPFGAGARTCLGQGFA 1471 +H DP+LW P+ ++F P RFS ++Y+PFGAG R C+G FA Sbjct: 400 WPLHRDPELW-PEPEKFKPERFSKENKDTFDPYTYMPFGAGPRNCIGMRFA 449
>Q27516:C13A8_CAEEL Putative cytochrome P450 CYP13A8 - Caenorhabditis elegans| Length = 509 Score = 127 bits (319), Expect = 1e-28 Identities = 107/420 (25%), Positives = 183/420 (43%), Gaps = 45/420 (10%) Frame = +2 Query: 356 EKWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRG--- 526 +KW KE+G ++ ++ G + +S PD+V++I L ++ H P+ G Sbjct: 53 QKWTKEYGKIYGFTEGMQKVMVISDPDLVQEI-----LVKQYDNFYGRKHNPVQGDPDKD 107 Query: 527 ----ILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDI 694 I+ + G W R I AP F +K ++ M DS Q L++ ++G V++ Sbjct: 108 KDIHIVGAQGFRWKRLRTITAPAFSNGSIKKVLTTMEDSTQELMKKLREE-SENGKAVNM 166 Query: 695 KIDDDIRAYSADVISRTCFG--------SSYVKGKKIFLKLRELQKAVSKPNVLAEMTGL 850 + + Y+ DVISR G + +K K F + Q + ++ L Sbjct: 167 HLF--YQEYTFDVISRVAMGQPDSQMFKNPLLKDVKGFFEHNRWQIWMFSGGFPFAVSFL 224 Query: 851 RFFPTKKNRQAWGLHKQVHRLILEIVK--------------ESGEDKNLLRAILHSA--- 979 ++ K + G V + + + V E GE + + L++ Sbjct: 225 KWLFIKVGKFGAGPFIVVQKSVTDAVMSRIAQREADKKHGVEPGEAADYIDMFLNARAEV 284 Query: 980 ------------SSSKVGLGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQD 1123 SSS I+ C AG+++TA++ ++ L L+P+ Q Sbjct: 285 EHFGESNDEFHKSSSYNNRQLTTQEIISQCFVFLVAGFDTTAISLSYVTYFLALNPKIQS 344 Query: 1124 RVRQEVLEVCGGRPLDSQSLQKMKNLTMVIQETLRLYPAGAFV-SRMALQELKLGGVHIP 1300 +++ EV + C + L K+K + VI+E+LRL+P +F SR ++ +G + Sbjct: 345 KLQDEVDKECPNDEITFDQLSKLKYMDNVIKESLRLFPFASFANSRRCMRNTVIGEQIVE 404 Query: 1301 KGVNIYIPVSTMHLDPKLWGPDAKEFNPARFSDARPQLHSYLPFGAGARTCLGQGFATAE 1480 GV++ I T+H D +WG D +EF P R+ +YL FGAG R CLG FA E Sbjct: 405 AGVDVMIDTWTLHHDKNVWGNDVEEFKPERWDSPLTPQQAYLSFGAGPRVCLGMRFALLE 464
>Q27520:C13A1_CAEEL Putative cytochrome P450 CYP13A1 - Caenorhabditis elegans| Length = 519 Score = 127 bits (319), Expect = 1e-28 Identities = 107/424 (25%), Positives = 182/424 (42%), Gaps = 50/424 (11%) Frame = +2 Query: 359 KWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDL--GKSSYLKATHEPLFGRGIL 532 +W K+ G ++ ++ G + L +S P++V ++ + + K + ++ E + Sbjct: 60 EWTKKFGKIYGFTEGTLKTLVISDPELVHEVFVTQYDNFYGRKRNPIQGDSEKEKRTNLF 119 Query: 533 KSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDI 712 + G W R I +P F ++ + + DSA LL E + S G I + Sbjct: 120 AAQGFRWKRLRAISSPTFSNSSLRKLYQTVEDSALELLRHIEKQ---SAGGKQIDMLKFY 176 Query: 713 RAYSADVISRTCFG---SSYVKGKKIFLKLRELQKAVSKPNVLAEMTGLRFFPT------ 865 + ++ DVI R G S K + + + Q +K ++ + FPT Sbjct: 177 QEFTLDVIGRIAMGQTDSQMFKNPIMPIVSKLFQGNFAKLFLIGGI-----FPTFLVEII 231 Query: 866 ----KKNRQAWGLHKQVHRLILEIVK--------------ESGEDKNLLRAILHSASSSK 991 KN + G ++++ + L+ + E GE + + L + + Sbjct: 232 RQILLKNLKV-GSFRKINEITLDAIHNRIKQREEDQKNGIEIGEPADFIDLFLDAKAEDV 290 Query: 992 VGLGE----------------AENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQD 1123 GE IV C AG+++TA++ ++ LL HPE Q Sbjct: 291 EHFGENNGDFSKSTTYTNRQLTTEEIVGQCTVFLIAGFDTTALSLSYATYLLATHPEIQK 350 Query: 1124 RVRQEVLEVCGGRPLDSQSLQKMKNLTMVIQETLRLYPAGAFV-SRMALQELKLGGVHIP 1300 ++++EV C + L K+K + V +E LRLYP GAF SR ++ KLG + + Sbjct: 351 KLQEEVNRECPNPEVTIDQLSKLKYMECVFKEALRLYPLGAFANSRRCMRNTKLGNMKVE 410 Query: 1301 KGVNIYIPVSTMHLDPKLWGPDAKEFNPARF----SDARPQLHSYLPFGAGARTCLGQGF 1468 G I + T+H DP +WG DA++F P R+ SD Q Y+PFG G R C+G Sbjct: 411 VGTMIQVDTWTLHTDPNIWGDDAEDFKPERWQTPNSDQIYQKSGYIPFGLGPRQCIGMRL 470 Query: 1469 ATAE 1480 A E Sbjct: 471 AYME 474
>Q964T1:CP4CU_BLAGE Cytochrome P450 4c21 - Blattella germanica (German cockroach)| Length = 501 Score = 127 bits (318), Expect = 2e-28 Identities = 105/411 (25%), Positives = 191/411 (46%), Gaps = 32/411 (7%) Frame = +2 Query: 344 LPFYEKWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGR 523 + + E+ +++ P+ + GN F+++S P+++ + + L ++L G Sbjct: 58 MTWIEEILEKYKPLILWYFGNRPFVNISSPELIEVV--LRNTQLIDKAFLYDLFHSWLGT 115 Query: 524 GILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKID 703 G+L S+G W RKII P F ++G + + + ++ L+ ++ K G I Sbjct: 116 GLLTSSGAKWHQHRKIITPTFHFSILEGFITIFAEKSEILVR----KLQKEVGRGPFFIR 171 Query: 704 DDIRAYSADVISRTCFGSSYVKGKKIFLKLRELQKAVSK-PNVLAE-MTGLRFFPT---K 868 + + D+I T G+S + F E A++K +VL++ M +P K Sbjct: 172 QYVSNCALDIICETAMGTSVNAQDEGF---SEYVTAINKMTDVLSDRMANPLLYPEFIFK 228 Query: 869 KNRQAWGLHKQ----VHRLILEIVKESGEDKNLLRAILHSASSSKVGLGEAENF------ 1018 W HK+ ++ + +I++E E++ + + ++ + +G + F Sbjct: 229 LTPYYW-THKKCLKVLNGFVNKIIQERKEERKKSK-VTQTSEDADIGKKKRVPFLDTLLD 286 Query: 1019 ------------IVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGG- 1159 I++ + F G+++ + W L LG HPE Q+ +EV ++ G Sbjct: 287 ASEDDNKLTDTDILEEVHTFMFEGHDTVSAAMTWLLFELGHHPEIQEEAYKEVQDIFQGS 346 Query: 1160 -RPLDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKLGGVHIPKGVNIYIPVSTM 1336 R L M L VI+E+LRL+P+ + R A Q+ +LGG IP G NI V + Sbjct: 347 DRVPTMADLNNMNYLERVIKESLRLHPSVIYFVREAHQDFELGGYTIPAGTNIDFSVPFI 406 Query: 1337 HLDPKLWGPDAKEFNPARFSDAR---PQLHSYLPFGAGARTCLGQGFATAE 1480 H +P+++ P+ + FNP F R ++Y+PF AG R C+GQ FA E Sbjct: 407 HRNPEIF-PNPRCFNPDNFLPDRVVNRHPYAYIPFSAGPRNCIGQRFALLE 456
>Q91WL5:CP4AC_MOUSE Cytochrome P450 4A12 - Mus musculus (Mouse)| Length = 508 Score = 127 bits (318), Expect = 2e-28 Identities = 102/394 (25%), Positives = 175/394 (44%), Gaps = 26/394 (6%) Frame = +2 Query: 509 PLFGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTV 688 P GRG+L +G+ W R+++ P F D +K ++M DS + +L+ WE V G Sbjct: 123 PWIGRGLLLLDGQTWFQHRRMLTPAFHYDILKPYTEIMADSVRVMLDKWEQIV---GQDS 179 Query: 689 DIKIDDDIRAYSADVISRTCFGSSYVKGKKIFLKLRELQKAVSKPNVLAEMTGLRFFPT- 865 ++I I + D I + F S+ ++ K + +AV N L F Sbjct: 180 TLEIFRHITLMTLDTIMKCAF--SHEGSVQLDRKYKSYIQAVEDLNDLVFSRVRNIFHQN 237 Query: 866 -----------KKNRQAWGLHKQVHRLI----LEIVKESGEDK-------NLLRAILHSA 979 K N H ++I +++ E +K + L +L + Sbjct: 238 DIIYRVSSNGCKANSACKLAHDHTDQVIKSRRIQLQDEEELEKLKKKRRLDFLDILLFAR 297 Query: 980 SSSKVGLGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCG- 1156 + L + + + + F G+++TA +W L +PE Q R R+E+ + G Sbjct: 298 MENGKSLSDKD--LRAEVDTFMFEGHDTTASGISWIFYALATNPEHQQRCRKEIQSLLGD 355 Query: 1157 GRPLDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKL-GGVHIPKGVNIYIPVST 1333 G + L KM TM I+E LR+YP VSR + G +PKG+++ + Sbjct: 356 GTSITWNDLDKMPYTTMCIKEALRIYPPVPSVSRELSSPVTFPDGRSLPKGIHVMLSFYG 415 Query: 1334 MHLDPKLWGPDAKEFNPARFSDARPQ-LHSYLPFGAGARTCLGQGFATAEXXXXXXXXXX 1510 +H +P +W P+ + F+P+RF+ + HS+LPF GAR C+G+ FA E Sbjct: 416 LHHNPTVW-PNPEVFDPSRFAPGSSRHSHSFLPFSGGARNCIGKQFAMNELKVAVALTLL 474 Query: 1511 XFALRLSPLYQHSPALKLIVEPEFGVDITLTKVQ 1612 F L P P +++++ + G+ + L K+Q Sbjct: 475 RFELLPDPTRVPIPIPRIVLKSKNGIHLHLKKLQ 508
>Q64409:CP3AH_CAVPO Cytochrome P450 3A17 - Cavia porcellus (Guinea pig)| Length = 503 Score = 127 bits (318), Expect = 2e-28 Identities = 121/454 (26%), Positives = 197/454 (43%), Gaps = 30/454 (6%) Frame = +2 Query: 200 FRRQGIGGPRPSFPYGNMADXXXXXXXXXXXXXXXXXXXIVHDYRPAVLPFYEKWRKEHG 379 F++ GI GP+P +GN V YR + F + K++G Sbjct: 33 FKKLGIPGPKPLPLFGN-----------------------VLSYRKGIWNFDIECHKKYG 69 Query: 380 PVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHE-PLFGRGILK-----SN 541 ++ G L ++ PD+++ + L K Y T+ +F G +K S Sbjct: 70 NMWGLYDGPRPVLSITEPDMIKAV-------LVKECYSVFTNRRSIFPAGFMKKALSISK 122 Query: 542 GEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAY 721 E W R ++ F K+K M ++ L++ +K G V +K + AY Sbjct: 123 DEEWKRIRTQLSQNFTSGKLKEMFPIIKQYGDVLVKNLRQEAEK-GKPVQLK--EIFGAY 179 Query: 722 SADVISRTCFGSSY-----------VKGKKIF---LKLRELQKAVSKPNV--LAEMTGLR 853 S D+I T FG + K K+F L V P + L EM + Sbjct: 180 SMDIIIATAFGVNVDSLNNPHDPFVSKASKLFRFDFLSPFLLSVVIFPFLTQLYEMLNIS 239 Query: 854 FFPTKKNRQAWGLHKQVHRLILEIVKESGEDK--NLLRAILHSASSSKVGLGEAENFIVD 1027 FP R + + + E ES E + N L+ +L S + +A + + Sbjct: 240 IFP----RDSLNFFTKFVKRTKENHLESNEKQRVNFLQMMLKSQNFKDTESHKALSDVEI 295 Query: 1028 NCKSIYF--AGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGRPLDSQS-LQKMKN 1198 +SI+F AGYE+T+ T + + L HP+ Q +++QE+ + + + + +M+ Sbjct: 296 LAQSIFFIVAGYETTSSTLCFIMYSLATHPDVQKKLQQEIDKTLPNKAFPTYDVMMEMEY 355 Query: 1199 LTMVIQETLRLYPAGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEF 1378 L MV+ ETLRLYP + RM+ ++ ++ G+ PKG + IP +H D K W P+ EF Sbjct: 356 LDMVVNETLRLYPVTNRIERMSKKDFEINGMSFPKGTGVMIPSFALHRDSKYW-PEPDEF 414 Query: 1379 NPARFSDARPQ---LHSYLPFGAGARTCLGQGFA 1471 P RFS + + Y+PFG G R C+G A Sbjct: 415 RPERFSKKNKENIDPYIYMPFGNGPRNCIGMRMA 448
>P14581:CP4A7_RABIT Cytochrome P450 4A7 precursor - Oryctolagus cuniculus (Rabbit)| Length = 511 Score = 126 bits (317), Expect = 3e-28 Identities = 116/428 (27%), Positives = 198/428 (46%), Gaps = 25/428 (5%) Frame = +2 Query: 401 GNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRGILKSNGEAWAHQRKIIAP 580 G+ +FL PD ++ I L S + SY + P G G+L G+ W R+++ P Sbjct: 92 GSELFLICYDPDYMKTI-LGRSDPKARVSY--SFLAPWIGYGLLLLEGQTWFQHRRMLTP 148 Query: 581 EFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAYSADVISRTCF--- 751 F D +K V LMVDS Q +L+ E K ++I + + + + I + F Sbjct: 149 AFHYDILKPYVGLMVDSVQVMLDKLEKLARKDA---PLEIYEHVSLMTLETIMKCAFSHQ 205 Query: 752 GSSYVKG---KKIFLKLRELQKAVSKP--NVLAEMTGL-RFFPTKK--NRQAWGLHKQVH 907 GS ++ K +REL + NV + L R P + +R H+ Sbjct: 206 GSVQLESRTSKSYIQAVRELSDLALQRVRNVFHQSDFLYRLSPEGRLSHRACQLAHEHTD 265 Query: 908 RLILEI---VKESGEDKNLLR--------AILHSASSSKVGLGEAENFIVDNCKSIYFAG 1054 R+I + +++ GE + + R +L + + L + + + + F G Sbjct: 266 RVIQQRKAQLQQEGELEKVRRKRRLDFLDVLLFAKMENGSSLSDQD--LRAEVDTFMFEG 323 Query: 1055 YESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCG-GRPLDSQSLQKMKNLTMVIQETLRL 1231 +++TA +W L HPE Q R R+E+ + G G + + L KM TM I+E LRL Sbjct: 324 HDTTASGISWIFYALATHPEHQHRCREEIQGLLGDGASITWEHLDKMPYTTMCIKEALRL 383 Query: 1232 YPAGAFV-SRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARFSDARP 1408 YP V S+++ G +PKG+ I + + +H +PK+W P+ + F+P+RF+ Sbjct: 384 YPPVPGVGSKLSSPVTFPDGRSLPKGIIITLSIYGLHHNPKVW-PNPEVFDPSRFAPGSA 442 Query: 1409 Q-LHSYLPFGAGARTCLGQGFATAEXXXXXXXXXXXFALRLSPLYQHSPALKLIVEPEFG 1585 + H++LPF G+R C+G+ FA E F L P P +L+++ + G Sbjct: 443 RHSHAFLPFSGGSRNCIGKQFAMNELKVAVALTLVRFELLPDPTRVPIPITRLVLKSKNG 502 Query: 1586 VDITLTKV 1609 + + L K+ Sbjct: 503 IHLRLRKL 510
>Q27589:CP4D2_DROME Cytochrome P450 4d2 - Drosophila melanogaster (Fruit fly)| Length = 501 Score = 126 bits (316), Expect = 3e-28 Identities = 122/461 (26%), Positives = 208/461 (45%), Gaps = 41/461 (8%) Frame = +2 Query: 341 VLPFYEKWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLD--LGKSSYLKATHEPL 514 ++ F +K ++++G ++ + + + + + P RDI +S + K++ K + L Sbjct: 54 IMDFVKKNQRKYGRLYRVWILHQLAVFSTDP---RDIEFVLSSQQHITKNNLYKLLNCWL 110 Query: 515 FGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDI 694 G G+L S G W +RKII P F ++ V++ + ++E ++R D G I Sbjct: 111 -GDGLLMSTGRKWHGRRKIITPTFHFKILEQFVEIFDQQSAVMVEQLQSRAD---GKTPI 166 Query: 695 KIDDDIRAYSADVISRTCFGSSYVKGKKIFLKLRELQKAVSKPNVLAEMTGLRFF----- 859 I I + D+I+ T G+ K L +Q N+L + RF Sbjct: 167 NIFPVICLTALDIIAETAMGTKINAQKNP--NLPYVQAVNDVTNILIK----RFIHAWQR 220 Query: 860 ---------PTKKNRQAWGLHKQVHRLILEIVKESGE-------------DKNLL----- 958 PT+ RQ + K +H I++E E + N L Sbjct: 221 VDWIFRLTQPTEAKRQDKAI-KVMHDFTENIIRERRETLVNNSKETTPEEEVNFLGQKRR 279 Query: 959 RAILHSASSSKV-GLGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQ 1135 A+L S + G ++ I + + F G+++T ++CL + HPE Q R++Q Sbjct: 280 MALLDVLLQSTIDGAPLSDEDIREEVDTFMFEGHDTTTSAISFCLYEISRHPEVQQRLQQ 339 Query: 1136 EVLEVCGG---RPLDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKLGGVHIPKG 1306 E+ +V G P+ + L ++K + VI+E+LRL+P + R +++++ G HIP G Sbjct: 340 EIRDVLGEDRKSPVTLRDLGELKFMENVIKESLRLHPPVPMIGRWFAEDVEIRGKHIPAG 399 Query: 1307 VNIYIPVSTMHLDPKLW-GPDAKEFNPARFSDARPQLH--SYLPFGAGARTCLGQGFATA 1477 N + + + DP+ + PD EF P RF PQ+H +Y+PF AG R C+GQ FA Sbjct: 400 TNFTMGIFVLLRDPEYFESPD--EFRPERFDADVPQIHPYAYIPFSAGPRNCIGQKFAML 457 Query: 1478 EXXXXXXXXXXXFALRLSPLYQHSPALKLIVEPEFGVDITL 1600 E +S L +H L L EP ++I L Sbjct: 458 E-----------MKSTVSKLLRHFELLPLGPEPRHSMNIVL 487
>Q64406:CP3AF_CAVPO Cytochrome P450 3A15 - Cavia porcellus (Guinea pig)| Length = 503 Score = 126 bits (316), Expect = 3e-28 Identities = 116/448 (25%), Positives = 196/448 (43%), Gaps = 24/448 (5%) Frame = +2 Query: 200 FRRQGIGGPRPSFPYGNMADXXXXXXXXXXXXXXXXXXXIVHDYRPAVLPFYEKWRKEHG 379 F++ GI GP+P +GN V YR + F + RK++G Sbjct: 33 FKKLGIPGPKPLPLFGN-----------------------VLSYRKGMWSFDIECRKKYG 69 Query: 380 PVFTYSMGNVVFLHVSRPDVVRDINL--CVSLDLGKSSYLKATHEPLFGRGILKSNGEAW 553 ++ G L ++ PD+++ + + C S+ + S + + + S E W Sbjct: 70 NMWGLYDGPQPVLAITEPDMIKAVLVKECYSVFTNRRSLVPVG---FMKKSVSLSEDEEW 126 Query: 554 AHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAYSADV 733 R ++P F K+K M ++ L++ +K G V +K + AY D+ Sbjct: 127 KRIRTQLSPNFTSGKLKEMFPIIKQYGDVLVKNLRQEAEK-GKPVQLK--EIFGAYGMDI 183 Query: 734 ISRTCFGSSY-----------VKGKKIF---LKLRELQKAVSKPNV--LAEMTGLRFFPT 865 I T FG + K K+F L V P + L EM + FP Sbjct: 184 IIATAFGVNVDSLNNPHDPFVSKANKLFRFDFLSPFLLSTVMFPFLTQLYEMLSISIFPR 243 Query: 866 KKNRQAWGLHKQVHRLILEIVKESGEDKNLLRAILHSASSSKVGLGEAENFIVDNCKSIY 1045 + K+ LE K+ + N L+ +L+S + +A + + +SI Sbjct: 244 DSLKFFTKFVKKTKENHLESNKK--QRVNFLQMMLNSQNFKDTESHKALSDVEILAQSII 301 Query: 1046 F--AGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGRPLDSQS-LQKMKNLTMVIQ 1216 F AGYE+++ T + + L HP+ Q ++ QE+ + + + + +M+ L MV+ Sbjct: 302 FIFAGYETSSSTLSCIMYSLATHPDVQKKLHQEIDKTLPNKAFPTYDVMMEMEYLDMVVN 361 Query: 1217 ETLRLYPAGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARFS 1396 ETLRLYP + RM+ ++ ++ G+ PKG + IP +H D K W P+ EF P RFS Sbjct: 362 ETLRLYPVANRIERMSKKDFEINGMSFPKGTLVMIPSFALHRDSKYW-PEPDEFRPERFS 420 Query: 1397 DARPQ---LHSYLPFGAGARTCLGQGFA 1471 + + Y+PFG G R C+G+ A Sbjct: 421 KKNKENIDPYIYMPFGNGPRNCIGRRMA 448
>Q27515:C13A6_CAEEL Putative cytochrome P450 CYP13A6 - Caenorhabditis elegans| Length = 518 Score = 126 bits (316), Expect = 3e-28 Identities = 127/525 (24%), Positives = 219/525 (41%), Gaps = 52/525 (9%) Frame = +2 Query: 161 YTVWVVPQRLLAGFRRQGIGGPRPSFPYGNMADXXXXXXXXXXXXXXXXXXXIVHDYRPA 340 Y+VW+ + F R+GI GPR FP M I H+ P Sbjct: 16 YSVWI-----WSYFIRKGIKGPR-GFPGIGML-----------------IQTIDHENPPF 52 Query: 341 VLPFYEKWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFG 520 + Y W K++GPV+ ++ G + +S P++V +I ++ P+ G Sbjct: 53 LK--YRDWTKQYGPVYGFTEGPQQTMIISEPEMVNEI-----FKKQFDNFYGRKLRPIIG 105 Query: 521 R-------GILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSG 679 I + G+ W R + +P F + ++ + + + + +L E +V K+ Sbjct: 106 DPEKDKRVNIFSTQGKRWKRLRTLSSPSFSNNSLRKVRNSVQECGTEILWNIEQKVRKNE 165 Query: 680 GTVDIKIDDDIRAYSADVISRTCFGSSYVKGKK----------------IFLKLRELQKA 811 DI + + Y+ VISR G S K +FL Sbjct: 166 ---DIDMLIVYQEYTLGVISRIALGQSESNMFKNPLLPKVQAIFNGSWHVFLITGIFPPL 222 Query: 812 VSKPNVLAEMTGLRFFPTKK--NRQAWGLHKQVHRLILEIVK--ESGEDKNLLRAILHS- 976 +++M F P K + + ++ + + +K E GE ++ + L + Sbjct: 223 AGVFRKMSKMLPASFIPAFKIFDLIEVAVQARIDQRAKDEIKGVEPGEPQDFIDLFLDAR 282 Query: 977 ---------------ASSSKVGLGEAENF--IVDNCKSIYFAGYESTAVTAAWCLMLLGL 1105 A SS V + + F I+ C AG+++TA++ ++ LL Sbjct: 283 VPDVKILSGEANEDFAKSSVVKINKELTFDEIIAQCFVFLAAGFDTTALSLSYATYLLAT 342 Query: 1106 HPEWQDRVRQEVLEVCGGRPLDSQSLQKMKNLTMVIQETLRLYPAGAFV-SRMALQELKL 1282 HPE Q ++++EV C + L K+K L V++ETLRLYP G +R ++E + Sbjct: 343 HPEIQTKLQEEVDRECPDPEIFFDHLSKLKYLECVMKETLRLYPLGTTANTRKCMRETTI 402 Query: 1283 GGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARFSDAR----PQLHSYLPFGAGART 1450 GV+ +G+NI + T+H +P++WG D ++F P R+ + SY+PFG+G R Sbjct: 403 NGVNFDEGMNIQVDTWTLHHNPRIWGEDVEDFKPERWENGACEHLEHNGSYIPFGSGPRQ 462 Query: 1451 CLGQGFATAEXXXXXXXXXXXFALRLSPLYQHSPAL--KLIVEPE 1579 C+G A E ++ R + Q L KL + PE Sbjct: 463 CIGMRLAQMEQKILLAQILKEYSFRTTKNTQIPVKLVGKLTLSPE 507
>Q9EP75:CP4FE_MOUSE Cytochrome P450 4F14 - Mus musculus (Mouse)| Length = 524 Score = 125 bits (315), Expect = 4e-28 Identities = 107/402 (26%), Positives = 187/402 (46%), Gaps = 36/402 (8%) Frame = +2 Query: 383 VFTYSMGNVVFLHVSRP-------DVVRDINLCVSLDLGKSSYLKATHEPLFGRGILKSN 541 V TY G ++++ P D+VR I + K + +P G G+L S Sbjct: 81 VGTYPQGFLMWIGPMVPVITLCHSDIVRSILNASAAVALKDVIFYSILKPWLGDGLLVSA 140 Query: 542 GEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAY 721 G+ W+ R+++ P F + +K V + DS + W+ + S G+ + + + + Sbjct: 141 GDKWSRHRRMLTPAFHFNILKPYVKIFNDSTNIMHAKWQRLI--SDGSARLDMFEHVSLM 198 Query: 722 SADVISRTCFG---SSYVKGKKIFLKLRELQKAVSKPN--------VLAEMT--GLRFFP 862 + D + + F + K + + EL V+K + +L +T G+RF Sbjct: 199 TLDSLQKCVFSFDSNCQEKSSEYIAAILELSALVAKRHQQPLMFMDLLYNLTPDGMRFRK 258 Query: 863 TKKNRQAW--GLHKQVHRLILE-----IVKESGEDKNLLRAILHSASSSKVGLGEAENFI 1021 + + ++ HR + + +K + K L + S + G ++ I Sbjct: 259 ACNVVHEFTDAVIRERHRTLPDQGLDDFLKSKAKSKTLDFIDVLLLSKDEDGKELSDEDI 318 Query: 1022 VDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGR---PLDSQSLQKM 1192 + F G+++TA +W L L HPE+Q+R RQEV E+ GR ++ L ++ Sbjct: 319 RAEADTFMFEGHDTTASGLSWILYNLARHPEYQERCRQEVQELLRGREPEEIEWDDLAQL 378 Query: 1193 KNLTMVIQETLRLYPAGAFVSRMALQELKL-GGVHIPKGVNIYIPVSTMHLDPKLWGPDA 1369 LTM I+E+LRL+P +SR Q++ L G IPKG+ I + +H +P +W PD Sbjct: 379 PFLTMCIKESLRLHPPVTVISRCCTQDILLPDGRTIPKGIICLISIFGIHHNPSVW-PDP 437 Query: 1370 KEFNPARF-----SDARPQLHSYLPFGAGARTCLGQGFATAE 1480 + ++P RF D+ P +++PF AG R C+GQ FA +E Sbjct: 438 EVYDPFRFDPENIKDSSPL--AFIPFSAGPRNCIGQTFAMSE 477
>Q86W10:CP4Z1_HUMAN Cytochrome P450 4Z1 - Homo sapiens (Human)| Length = 505 Score = 125 bits (313), Expect = 7e-28 Identities = 106/427 (24%), Positives = 192/427 (44%), Gaps = 27/427 (6%) Frame = +2 Query: 410 VFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRGILKSNGEAWAHQRKIIAPEFF 589 +F V PD + + + KS+ E GRG++ +G W R+I+ P F Sbjct: 89 MFFSVHDPDYAK---ILLKRQDPKSAVSHKILESWVGRGLVTLDGSKWKKHRQIVKPGFN 145 Query: 590 LDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAYSADVISRTCFGSSYVK 769 + +K + +M +S + +L WE + ++ +++ + + D I + F S+ Sbjct: 146 ISILKIFITMMSESVRMMLNKWEEHIAQNSR---LELFQHVSLMTLDSIMKCAF--SHQG 200 Query: 770 GKKIFLKLRELQKAV--------SKPNVLAEMTGLRFFPTKKNRQAWGLHKQVHRLILEI 925 ++ L KAV + N L F + + + ++++H+ ++ Sbjct: 201 SIQLDSTLDSYLKAVFNLSKISNQRMNNFLHHNDLVFKFSSQGQIFSKFNQELHQFTEKV 260 Query: 926 V---KESGEDK-----------NLLRAILHSASSSKVGLGEAENFIVDNCKSIYFAGYES 1063 + KES +DK + L +L + S + EA+ + K+ FAG+++ Sbjct: 261 IQDRKESLKDKLKQDTTQKRRWDFLDILLSAKSENTKDFSEAD--LQAEVKTFMFAGHDT 318 Query: 1064 TAVTAAWCLMLLGLHPEWQDRVRQEVLEVCG-GRPLDSQSLQKMKNLTMVIQETLRLYPA 1240 T+ +W L L +PE Q R R E+ E+ G G + + L +M TM I+E LRLY Sbjct: 319 TSSAISWILYCLAKYPEHQQRCRDEIRELLGDGSSITWEHLSQMPYTTMCIKECLRLYAP 378 Query: 1241 GAFVSRMALQELKL-GGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARFS-DARPQL 1414 +SR+ + + G +P G+ ++I + +H +P W D + FNP RFS + ++ Sbjct: 379 VVNISRLLDKPITFPDGRSLPAGITVFINIWALHHNPYFW-EDPQVFNPLRFSRENSEKI 437 Query: 1415 HSY--LPFGAGARTCLGQGFATAEXXXXXXXXXXXFALRLSPLYQHSPALKLIVEPEFGV 1588 H Y +PF AG R C+GQ FA E F L P +++++ + G+ Sbjct: 438 HPYAFIPFSAGLRNCIGQHFAIIECKVAVALTLLRFKLAPDHSRPPQPVRQVVLKSKNGI 497 Query: 1589 DITLTKV 1609 + KV Sbjct: 498 HVFAKKV 504
>P14580:CP4A6_RABIT Cytochrome P450 4A6 precursor - Oryctolagus cuniculus (Rabbit)| Length = 510 Score = 125 bits (313), Expect = 7e-28 Identities = 103/394 (26%), Positives = 175/394 (44%), Gaps = 26/394 (6%) Frame = +2 Query: 509 PLFGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTV 688 P G G+L NG+ W R+++ P F D +K V LM DS Q +L+ WE V + Sbjct: 125 PWIGYGLLLLNGQTWFQHRRMLTPAFHYDILKPYVGLMADSVQIMLDKWEQLVSQDSS-- 182 Query: 689 DIKIDDDIRAYSADVISRTCFGSSYVKGKKIFLKLRELQKAVSKPNVL----------AE 838 +++ DI + D I + F S+ ++ + +AV N L Sbjct: 183 -LEVFQDISLMTLDTIMKCAF--SHQGSVQLDRNSQSYIQAVGDLNNLFFSRVRNVFHQS 239 Query: 839 MTGLRFFPTKK--NRQAWGLHKQVHRLILEI---VKESGEDKNLLR--------AILHSA 979 T R P + +R H+ R+I + +++ GE + + R +L + Sbjct: 240 DTIYRLSPEGRLSHRACQLAHEHTDRVIQQRKAQLQQEGELEKVRRKRRLDFLDVLLFAK 299 Query: 980 SSSKVGLGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCG- 1156 + L + + + + F G+++TA +W L HPE Q R R+E+ + G Sbjct: 300 MENGSSLSDQD--LRAEVDTFMFEGHDTTASGISWIFYALATHPEHQHRCREEIQGLLGD 357 Query: 1157 GRPLDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKL-GGVHIPKGVNIYIPVST 1333 G + + L +M TM I+E LRLYP V R + G +PKGV + + + Sbjct: 358 GASITWEHLDQMPYTTMCIKEALRLYPPVPGVGRQLSSPVTFPDGRSLPKGVIVTLSIYA 417 Query: 1334 MHLDPKLWGPDAKEFNPARFSDARPQ-LHSYLPFGAGARTCLGQGFATAEXXXXXXXXXX 1510 +H +PK+W P+ + F+P F+ + H++LPF G R C+G+ FA E Sbjct: 418 LHHNPKVW-PNPEVFDPFPFAPGSARHSHAFLPFSGGPRNCIGKQFAMNELKVAVALTLV 476 Query: 1511 XFALRLSPLYQHSPALKLIVEPEFGVDITLTKVQ 1612 F L P +L+++ G+ + L K++ Sbjct: 477 RFELLPDPKRVPDQKPRLVLKSSNGIHLRLRKLR 510
>P98187:CP4F8_HUMAN Cytochrome P450 4F8 - Homo sapiens (Human)| Length = 520 Score = 124 bits (311), Expect = 1e-27 Identities = 108/400 (27%), Positives = 174/400 (43%), Gaps = 34/400 (8%) Frame = +2 Query: 383 VFTYSMGNVVFL-------HVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRGILKSN 541 V TY G V +L ++ PD+VR + K T +P G G+L S Sbjct: 81 VATYPQGFVRWLGPITPIINLCHPDIVRSVINTSDAITDKDIVFYKTLKPWLGDGLLLSV 140 Query: 542 GEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAY 721 G+ W H R+++ P F + +K + + SA + W+ R+ G T + + + I Sbjct: 141 GDKWRHHRRLLTPAFHFNILKPYIKIFSKSANIMHAKWQ-RLAMEGSTC-LDVFEHISLM 198 Query: 722 SADVISRTCFG---SSYVKGKKIFLKLRELQKAVSKPN-VLAEMTGLRFFPTKKNRQAWG 889 + D + + F + K + + EL V K N +F T R+ Sbjct: 199 TLDSLQKCIFSFDSNCQEKPSEYITAIMELSALVVKRNNQFFRYKDFLYFLTPCGRRFHR 258 Query: 890 LHKQVHRLILEIVKE----------------SGEDKNLLRAILHSASSSKVGLGEAENFI 1021 + VH +++E + K L + S K G ++ I Sbjct: 259 ACRLVHDFTDAVIQERRRTLTSQGVDDFLQAKAKSKTLDFIDVLLLSEDKNGKELSDEDI 318 Query: 1022 VDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGR---PLDSQSLQKM 1192 + F G+++TA +W L L HPE+Q+R RQEV E+ R ++ L ++ Sbjct: 319 RAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELLKDREPKEIEWDDLAQL 378 Query: 1193 KNLTMVIQETLRLYPAGAFVSRMALQELKLGGVH-IPKGVNIYIPVSTMHLDPKLWGPDA 1369 LTM ++E+LRL+P +R Q++ L IPKG I + +H +P +W PD Sbjct: 379 PFLTMCLKESLRLHPPIPTFARGCTQDVVLPDSRVIPKGNVCNINIFAIHHNPSVW-PDP 437 Query: 1370 KEFNPARFSDARPQLHS---YLPFGAGARTCLGQGFATAE 1480 + ++P RF Q S ++PF AG R C+GQ FA AE Sbjct: 438 EVYDPFRFDPENAQKRSPMAFIPFSAGPRNCIGQKFAMAE 477
>P51869:CP4F4_RAT Cytochrome P450 4F4 - Rattus norvegicus (Rat)| Length = 522 Score = 124 bits (310), Expect = 2e-27 Identities = 108/400 (27%), Positives = 180/400 (45%), Gaps = 34/400 (8%) Frame = +2 Query: 383 VFTYSMGNVVFLH-------VSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRGILKSN 541 V TY G + +L + PDV+R + + K + +P G G+L S+ Sbjct: 81 VATYPQGFMTWLGPILPIITLCHPDVIRSVLSASASVALKEVIFYSFLKPWLGDGLLLSD 140 Query: 542 GEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAY 721 G+ W+ R+++ P F + +K V + DS + W+ SGG+ + + +I Sbjct: 141 GDKWSCHRRMLTPAFHFNILKPYVKIFNDSTNIMHAKWQDLA--SGGSARLDMFKNISLM 198 Query: 722 SADVISRTCFG---SSYVKGKKIFLKLRELQKAVSKP-NVLAEMTGLRFFPTKKNRQAWG 889 + D + + F + K + + EL V+K L T + T R+ Sbjct: 199 TLDSLQKCVFSFDSNCQEKPSEYISAILELSALVAKRYQQLLLHTDSLYQLTHNGRRFHK 258 Query: 890 LHKQVHRLILEIVK------ESGEDKNLLRAILHSASSSKV----------GLGEAENFI 1021 K VH +++ S + ++L+A S + + G ++ I Sbjct: 259 ACKLVHNFTDAVIQGRRRALPSQHEDDILKAKARSKTLDFIDVLLLTKDEDGKELSDEDI 318 Query: 1022 VDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGR---PLDSQSLQKM 1192 + F G+++TA +W L L HPE+Q+R RQEV E+ R ++ L ++ Sbjct: 319 RAEADTFMFEGHDTTASGLSWILYNLARHPEYQERCRQEVRELLRDRESTEIEWDDLAQL 378 Query: 1193 KNLTMVIQETLRLYPAGAFVSRMALQELKL-GGVHIPKGVNIYIPVSTMHLDPKLWGPDA 1369 LTM I+E+LRL+P +SR Q++ L G IPKGV I + H +P +W PD Sbjct: 379 PFLTMCIKESLRLHPPVTVISRRCTQDIVLPDGRVIPKGVICIINIFATHHNPTVW-PDP 437 Query: 1370 KEFNPARFSDARPQLHS---YLPFGAGARTCLGQGFATAE 1480 + ++P RF + S ++PF AG R C+GQ FA E Sbjct: 438 EVYDPFRFDPENIKDRSPLAFIPFSAGPRNCIGQTFAMNE 477
>P24462:CP3A7_HUMAN Cytochrome P450 3A7 - Homo sapiens (Human)| Length = 503 Score = 123 bits (309), Expect = 2e-27 Identities = 129/472 (27%), Positives = 210/472 (44%), Gaps = 29/472 (6%) Frame = +2 Query: 143 LALYLYYTVWVVPQRLLAGFRRQGIGGPRPSFPYGNMADXXXXXXXXXXXXXXXXXXXIV 322 + LYLY T R F++ GI GP P GN Sbjct: 20 ILLYLYGT------RTHGLFKKLGIPGPTPLPFLGNALSFRKG----------------- 56 Query: 323 HDYRPAVLPFYEKWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKAT 502 Y + Y+K+RK G Y + L ++ PD+++ + L K Y T Sbjct: 57 --YWTFDMECYKKYRKVWG---IYDCQQPM-LAITDPDMIKTV-------LVKECYSVFT 103 Query: 503 HEPLFGR-GILKS-----NGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEAR 664 + FG G +K+ E W R +++P F K+K MV ++ L+ R Sbjct: 104 NRRPFGPVGFMKNAISIAEDEEWKRIRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLR-R 162 Query: 665 VDKSGGTVDIKIDDDIRAYSADVISRTCFGSS----------YVKGKKIFLKLRELQKAV 814 ++G V +K AYS DVI+ T FG S +V+ K L+ L V Sbjct: 163 EAETGKPVTLK--HVFGAYSMDVITSTSFGVSIDSLNNPQDPFVENTKKLLRFNPLDPFV 220 Query: 815 SKPNV------LAEMTGLRFFPTKKNRQAWGLHKQVHRLILEIVKESGEDK-NLLRAILH 973 V + E + FP K L K V ++ +KE+ + + + L+ ++ Sbjct: 221 LSIKVFPFLTPILEALNITVFPRKVISF---LTKSVKQIKEGRLKETQKHRVDFLQLMID 277 Query: 974 SASSSKVGLGEAENFIVDNCKSIYF--AGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLE 1147 S +S +A + + +SI F AGYE+T+ ++ + L HP+ Q +V++E+ Sbjct: 278 SQNSKDSETHKALSDLELMAQSIIFIFAGYETTSSVLSFIIYELATHPDVQQKVQKEIDT 337 Query: 1148 VCGGR-PLDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKLGGVHIPKGVNIYIP 1324 V + P ++ +++ L MV+ ETLRL+P + R+ +++++ G+ IPKGV + IP Sbjct: 338 VLPNKAPPTYDTVLQLEYLDMVVNETLRLFPVAMRLERVCKKDVEINGMFIPKGVVVMIP 397 Query: 1325 VSTMHLDPKLWGPDAKEFNPARFSDARP---QLHSYLPFGAGARTCLGQGFA 1471 +H DPK W + ++F P RFS + Y PFG+G R C+G FA Sbjct: 398 SYVLHHDPKYW-REPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFA 448
>Q27513:C13A4_CAEEL Putative cytochrome P450 CYP13A4 - Caenorhabditis elegans| Length = 520 Score = 123 bits (309), Expect = 2e-27 Identities = 116/492 (23%), Positives = 217/492 (44%), Gaps = 49/492 (9%) Frame = +2 Query: 152 YLYYTVWVVPQRLLAGFRRQGIGGPRPSFPYGNMADXXXXXXXXXXXXXXXXXXXIVHDY 331 +L Y +W+ + + R+G+ GPR FP+ + HDY Sbjct: 15 FLTYYIWI-----WSFWIRKGVKGPR-GFPFFGVI-------------------LKFHDY 49 Query: 332 RPAVLPFYEKWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEP 511 L +W K++G ++ + G L VS P+ V + V + + Y + T+ P Sbjct: 50 ENPGLLKLGEWTKKYGSIYGITEGVEKTLVVSNPEFVHE----VFVKQFDNFYGRKTN-P 104 Query: 512 LFG-------RGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVD 670 + G ++ + G W R + +P F ++ ++ + ++ L+ + Sbjct: 105 IQGDPNKNKRAHLVLAQGHRWKRLRTLASPTFSNKSLRKIMSTVEETVVELMRHLDEASA 164 Query: 671 KSGGTVDIKIDDDIRAYSADVISRTCFGS--SYVKGKKIFLKLRELQKAVSK-PNVLAEM 841 K G VD+ D + ++ D+I R G S + + K++E+ K K P ++A + Sbjct: 165 K-GKAVDLL--DYYQEFTLDIIGRIAMGQTESLMFRNPMLPKVKEIFKKGGKMPFLIAGV 221 Query: 842 TGLR-------FFPTKKNRQAWGLHKQVHRLILEIVKE-----------SGEDKNLLRAI 967 + F K A+G+ + + + + +++ SGE ++ + Sbjct: 222 FPIAGTLMRQLFMKFPKFSPAFGIMNTMEKALNKRLEQRAADKKAGIEPSGEPQDFIDLF 281 Query: 968 LHSASS-------SKVGLGEAENFIVDNCKSI----------YFAGYESTAVTAAWCLML 1096 L + ++ S +G ++E VD + AGY++TA++ ++ L Sbjct: 282 LDARANVDFIEEESTLGFAKSEVLKVDKHLTFDEIIGQLFVFLLAGYDTTALSLSYSSYL 341 Query: 1097 LGLHPEWQDRVRQEVLEVCGGRPLDSQSLQKMKNLTMVIQETLRLYPAGAFV-SRMALQE 1273 L HPE Q ++++EV C + + K+K + V++E LR+YP + V +R +++ Sbjct: 342 LATHPEIQKKLQEEVDRECPDPEVTFDQISKLKYMECVVKEALRMYPLASLVHNRKCMKK 401 Query: 1274 LKLGGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARFSDARPQLHS---YLPFGAGA 1444 + GV I +G N+ + T+H DPK+WG DA EF P R+ ++ YLPFG G Sbjct: 402 TNVLGVEIDEGTNVQVDTWTLHYDPKVWGDDASEFKPERWETGDELFYAKGGYLPFGMGP 461 Query: 1445 RTCLGQGFATAE 1480 R C+G A E Sbjct: 462 RICIGMRLAMME 473
>O08336:CYPE_BACSU Probable bifunctional P-450:NADPH-P450 reductase 2 [Includes:| Cytochrome P450 102 - Bacillus subtilis Length = 1054 Score = 123 bits (308), Expect = 3e-27 Identities = 123/453 (27%), Positives = 199/453 (43%), Gaps = 27/453 (5%) Frame = +2 Query: 344 LPFYEK-------WR--KEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLK 496 LP EK WR E GP+F + V + VS ++V ++ D L+ Sbjct: 19 LPHLEKEQLSQSLWRIADELGPIFRFDFPGVSSVFVSGHNLVAEVCDEKRFDKNLGKGLQ 78 Query: 497 ATHEPLFGRGILKS--NGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVD 670 E G G+ S + W +I+ P F +KG +M+D A L++ W Sbjct: 79 KVRE-FGGDGLFTSWTHEPNWQKAHRILLPSFSQKAMKGYHSMMLDIATQLIQKWS---- 133 Query: 671 KSGGTVDIKIDDDIRAYSADVISRTC-----FGSSYVKGKKIFLK--LRELQKAVSKPNV 829 + +I + DD+ + D I C F S Y + F+ LR L++A+++ Sbjct: 134 RLNPNEEIDVADDMTRLTLDTIG-LCGFNYRFNSFYRDSQHPFITSMLRALKEAMNQSKR 192 Query: 830 LAEM------TGLRFFPTKKNRQAWGLHKQVHRLILEIVKESGED-KNLLRAILHSASSS 988 L T L+F + ++ V R+I E E+ K+LL +L++ Sbjct: 193 LGLQDKMMVKTKLQF-----QKDIEVMNSLVDRMIAERKANPDENIKDLLSLMLYAKDPV 247 Query: 989 KVGLGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGRPL 1168 + EN I + AG+E+T+ ++ + L HPE + ++E V Sbjct: 248 TGETLDDEN-IRYQIITFLIAGHETTSGLLSFAIYCLLTHPEKLKKAQEEADRVLTDDTP 306 Query: 1169 DSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKLGGVH-IPKGVNIYIPVSTMHLD 1345 + + +Q++K + MV+ ETLRLYP S A ++ LGG + I KG + + + +H D Sbjct: 307 EYKQIQQLKYIRMVLNETLRLYPTAPAFSLYAKEDTVLGGEYPISKGQPVTVLIPKLHRD 366 Query: 1346 PKLWGPDAKEFNPARFSD-ARPQLHSYLPFGAGARTCLGQGFATAEXXXXXXXXXXXFAL 1522 WGPDA++F P RF D + H+Y PFG G R C+G FA E F L Sbjct: 367 QNAWGPDAEDFRPERFEDPSSIPHHAYKPFGNGQRACIGMQFALQEATMVLGLVLKHFEL 426 Query: 1523 RLSPLYQHSPALKLIVEPEFGVDITLTKVQTAS 1621 Y+ L ++P+ IT+ +TA+ Sbjct: 427 INHTGYELKIKEALTIKPD-DFKITVKPRKTAA 458
>Q9HBI6:CP4FB_HUMAN Cytochrome P450 4F11 - Homo sapiens (Human)| Length = 524 Score = 123 bits (308), Expect = 3e-27 Identities = 101/382 (26%), Positives = 169/382 (44%), Gaps = 27/382 (7%) Frame = +2 Query: 416 LHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRGILKSNGEAWAHQRKIIAPEFFLD 595 L + PD++R I + K +P G G+L S G+ W+ R+++ P F + Sbjct: 99 LILCHPDIIRPITSASAAVAPKDMIFYGFLKPWLGDGLLLSGGDKWSRHRRMLTPAFHFN 158 Query: 596 KVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAYSADVISRTCF---GSSYV 766 +K + + S + + W+ S G+ + + + I + D + + F + Sbjct: 159 ILKPYMKIFNKSVNIMHDKWQRLA--SEGSARLDMFEHISLMTLDSLQKCVFSFESNCQE 216 Query: 767 KGKKIFLKLRELQKAVSKPN--VLAEMTGLRFFPTKKNRQAWGLHK---------QVHRL 913 K + + EL V K N +L L + R H Q R Sbjct: 217 KPSEYIAAILELSAFVEKRNQQILLHTDFLYYLTPDGQRFRRACHLVHDFTDAVIQERRR 276 Query: 914 IL------EIVKESGEDKNLLRAILHSASSSKVGLGEAENFIVDNCKSIYFAGYESTAVT 1075 L + +K + K L + S + G ++ I + F G+++TA Sbjct: 277 TLPTQGIDDFLKNKAKSKTLDFIDVLLLSKDEDGKELSDEDIRAEADTFMFEGHDTTASG 336 Query: 1076 AAWCLMLLGLHPEWQDRVRQEVLEVCGGR---PLDSQSLQKMKNLTMVIQETLRLYPAGA 1246 +W L L HPE+Q++ RQEV E+ R ++ L ++ LTM I+E+LRL+P Sbjct: 337 LSWVLYHLAKHPEYQEQCRQEVQELLKDREPIEIEWDDLAQLPFLTMCIKESLRLHPPVP 396 Query: 1247 FVSRMALQELKL-GGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARFSDARPQLHS- 1420 +SR Q+ L G IPKG+ I + +H +P +W PD + ++P RF+ + S Sbjct: 397 VISRCCTQDFVLPDGRVIPKGIVCLINIIGIHYNPTVW-PDPEVYDPFRFNQENIKERSP 455 Query: 1421 --YLPFGAGARTCLGQGFATAE 1480 ++PF AG R C+GQ FA AE Sbjct: 456 LAFIPFSAGPRNCIGQAFAMAE 477
>P05184:CP3A3_HUMAN Cytochrome P450 3A3 - Homo sapiens (Human)| Length = 504 Score = 123 bits (308), Expect = 3e-27 Identities = 120/456 (26%), Positives = 202/456 (44%), Gaps = 32/456 (7%) Frame = +2 Query: 200 FRRQGIGGPRPSFPYGNMADXXXXXXXXXXXXXXXXXXXIVHDYRPAVLPFYEKWRKEHG 379 F++ GI GP P GN+ Y F + K++G Sbjct: 33 FKKLGIPGPTPLPFLGNILS-----------------------YHKGFCMFDMECHKKYG 69 Query: 380 PVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGR-GILKS-----N 541 V+ + G L ++ PD+++ L L K Y T+ FG G +KS Sbjct: 70 KVWGFYDGQQPVLAITDPDMIK-------LVLVKECYSVFTNREPFGPVGFMKSAISIAE 122 Query: 542 GEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAY 721 E W R +++P F K+K MV ++ L+ R ++G V +K D AY Sbjct: 123 DEEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLR-RERETGKPVTLK--DVFGAY 179 Query: 722 SADVISRTCFGSSY----------VKGKKIFLKLRELQKAVSKPNV------LAEMTGLR 853 S DVI+ + FG + V+ K L+ L V + E+ + Sbjct: 180 SMDVITSSSFGVNVDSLNNPQDPLVENTKKLLRFDFLDPFFLSITVFPFLIPILEVLNIC 239 Query: 854 FFPTKKNRQAWGLHKQVHRLILEIVKESGEDK-NLLRAILHSASSSKV-----GLGEAEN 1015 FP + L K V R+ ++++ + + + L+ ++ S +SK L + E Sbjct: 240 VFPREVTNF---LRKAVKRMKESRLEDTQKHRVDFLQLMIDSHKNSKETESHKALSDLE- 295 Query: 1016 FIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGR-PLDSQSLQKM 1192 +V FAGYE+T+ ++ + L HP+ Q ++++E+ V + P ++ +M Sbjct: 296 -LVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQM 354 Query: 1193 KNLTMVIQETLRLYPAGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWGPDAK 1372 + L MV+ ETLRL+P + R+ +++++ G+ IPKG + IP +H DPK W + + Sbjct: 355 EYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGWVVMIPSYALHRDPKYW-TEPE 413 Query: 1373 EFNPARFSDARP---QLHSYLPFGAGARTCLGQGFA 1471 +F P RFS + Y PFG+G R C+G FA Sbjct: 414 KFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFA 449
>Q9GJX5:CP4AL_PIG Cytochrome P450 4A21 - Sus scrofa (Pig)| Length = 504 Score = 122 bits (306), Expect = 5e-27 Identities = 101/391 (25%), Positives = 178/391 (45%), Gaps = 24/391 (6%) Frame = +2 Query: 509 PLFGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTV 688 P G G+L NG+ W +R+++ P F D +K V LM S Q +L+ WE V + Sbjct: 119 PWIGCGLLLLNGQMWFQRRRMLTPAFHYDILKPYVGLMAKSVQVMLDKWEQLVAQDPR-- 176 Query: 689 DIKIDDDIRAYSADVISRTCF---GSSYVKGK-----KIFLKLRELQKAVSKPNVLAEMT 844 ++I + + D I + F GS+ G + L+ L + + L Sbjct: 177 -LEIVGPVSLMTLDTIMKCAFSHQGSAQTDGDSQSYIQAIWDLKNLIFSRLRSAFLQNDI 235 Query: 845 GLRFFPTKKN--RQAWGLHKQVHRLIL---EIVKESGEDKNL--------LRAILHSASS 985 R P + R +H+ R+I +++ GE +N+ L +L + Sbjct: 236 IYRLSPEGRQCQRACQKVHQHTDRVIQLRKTHLQKEGEMENVKKKRHLDFLDILLFARME 295 Query: 986 SKVGLGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCG-GR 1162 + L + + + + AG++STA +W L L +PE Q R R+E+ + G G Sbjct: 296 NGNSLSDTD--VRAEVDTFMAAGHDSTASGISWVLYALASNPEHQQRCREEIQGLLGDGT 353 Query: 1163 PLDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKL-GGVHIPKGVNIYIPVSTMH 1339 + L +M TM I+E LRLYP V R + + G +P G+ + + + +H Sbjct: 354 SITWDHLDQMPYTTMCIKEALRLYPPVPSVGRELSKPITFPDGRSLPAGIILSLSIYGLH 413 Query: 1340 LDPKLWGPDAKEFNPARFSDARPQ-LHSYLPFGAGARTCLGQGFATAEXXXXXXXXXXXF 1516 +P++W P+ +EF+P+RF+ + H+++PF G+R C+G+ FA E F Sbjct: 414 HNPQVW-PNPEEFDPSRFAPGSARHSHAFMPFSGGSRNCIGKQFAMNEMKVVVALTLLRF 472 Query: 1517 ALRLSPLYQHSPALKLIVEPEFGVDITLTKV 1609 L P P ++++ + G+ + L K+ Sbjct: 473 ELAPDPSRIPVPIQGIVLKSKNGIHLNLRKI 503
>P05183:CP3A2_RAT Cytochrome P450 3A2 - Rattus norvegicus (Rat)| Length = 504 Score = 122 bits (305), Expect = 6e-27 Identities = 128/497 (25%), Positives = 221/497 (44%), Gaps = 37/497 (7%) Frame = +2 Query: 200 FRRQGIGGPRPSFPYGNMADXXXXXXXXXXXXXXXXXXXIVHDYRPAVLPFYEKWRKEHG 379 F++QGI GP+P P+ V +Y + F + K++G Sbjct: 33 FKKQGIPGPKP-LPF----------------------LGTVLNYYKGLGRFDMECYKKYG 69 Query: 380 PVFTYSMGNVVFLHVSRPDVVRDINL--CVSLDLGKSSYLKATHEPLFGRGILKSNGEAW 553 ++ G + ++++++ + C S+ + + + G+ + + E W Sbjct: 70 KIWGLFDGQTPVFAIMDTEMIKNVLVKECFSVFTNRRDFGPVG---IMGKAVSVAKDEEW 126 Query: 554 AHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAYSADV 733 R +++P F ++K M ++ L++ + + +G V +K AYS DV Sbjct: 127 KRYRALLSPTFTSGRLKEMFPIIEQYGDILVKYLKQEAE-TGKPVTMK--KVFGAYSMDV 183 Query: 734 ISRTCFGSS----------YVKGKKIFLKLRELQ----KAVSKPNV--LAEMTGLRFFPT 865 I+ T FG + +V+ K L+ V P + + EM + FP Sbjct: 184 ITSTSFGVNVDSLNNPKDPFVEKTKKLLRFDFFDPLFLSVVLFPFLTPIYEMLNICMFP- 242 Query: 866 KKNRQAWGLHKQVHRLILEIVKESGEDK------NLLRAILHSASSSK-----VGLGEAE 1012 K+ A+ K VHR +KE+ D + L+ +L++ ++SK L + E Sbjct: 243 -KDSIAF-FQKFVHR-----IKETRLDSKHKHRVDFLQLMLNAHNNSKDEVSHKALSDVE 295 Query: 1013 NFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGR-PLDSQSLQK 1189 I+ FAGYE+T+ T ++ L L HP+ Q ++++E+ + P + + Sbjct: 296 --IIAQSVIFIFAGYETTSSTLSFVLYFLATHPDIQKKLQEEIDGALPSKAPPTYDIVME 353 Query: 1190 MKNLTMVIQETLRLYPAGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWGPDA 1369 M+ L MV+ ETLRLYP G + R+ ++++L G+ IPKG + IP +H DP+ W P Sbjct: 354 MEYLDMVLNETLRLYPIGNRLERVCKKDIELDGLFIPKGSVVTIPTYALHHDPQHW-PKP 412 Query: 1370 KEFNPARFSDARP---QLHSYLPFGAGARTCLGQGFATAEXXXXXXXXXXXFALRLSPLY 1540 +EF+P RFS + YLPFG G R C+G FA F+ + P Sbjct: 413 EEFHPERFSKENKGSIDPYVYLPFGNGPRNCIGMRFALMNMKLALTKVLQNFSFQ--PCK 470 Query: 1541 QHSPALKL----IVEPE 1579 + LKL I+EPE Sbjct: 471 ETQIPLKLSRQAILEPE 487
>P04800:CP3A1_RAT Cytochrome P450 3A1 - Rattus norvegicus (Rat)| Length = 504 Score = 122 bits (305), Expect = 6e-27 Identities = 110/447 (24%), Positives = 198/447 (44%), Gaps = 23/447 (5%) Frame = +2 Query: 200 FRRQGIGGPRPSFPYGNMADXXXXXXXXXXXXXXXXXXXIVHDYRPAVLPFYEKWRKEHG 379 F++QGI GP+P +G V +Y + F + K++G Sbjct: 33 FKKQGIPGPKPLPFFGT-----------------------VLNYYMGLWKFDVECHKKYG 69 Query: 380 PVFTYSMGNVVFLHVSRPDVVRDINL--CVSLDLGKSSYLKATHEPLFGRGILKSNGEAW 553 ++ G + ++ ++++++ + C S+ + + + G+ + + E W Sbjct: 70 KIWGLFDGQMPLFAITDTEMIKNVLVKECFSVFTNRRDFGPVG---IMGKAVSVAKDEEW 126 Query: 554 AHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAYSADV 733 R +++P F ++K M ++ L++ + + +G V +K AYS DV Sbjct: 127 KRYRALLSPTFTSGRLKEMFPIIEQYGDILVKYLKQEAE-TGKPVTMK--KVFGAYSMDV 183 Query: 734 ISRTCFGSS----------YVKGKKIFLKLRELQ----KAVSKPNV--LAEMTGLRFFPT 865 I+ T FG + +V+ K L+ V P + + EM + FP Sbjct: 184 ITSTSFGVNVDSLNNPKDPFVEKTKKLLRFDFFDPLFLSVVLFPFLTPIYEMLNICMFPK 243 Query: 866 KKNRQAWGLHKQVHRLILEIVKESGEDKNLLRAILHSASSSKVGLGEAENFIVDNCKSIY 1045 ++ L+ V++ D L H+ S K + + I+ Sbjct: 244 DSIEFFKKFVYRMKETRLDSVQKHRVDFLQLMMNAHNDSKDKESHTALSDMEITAQSIIF 303 Query: 1046 -FAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGR-PLDSQSLQKMKNLTMVIQE 1219 FAGYE T+ T ++ L L HP+ Q ++++E+ + P ++ +M+ L MV+ E Sbjct: 304 IFAGYEPTSSTLSFVLHSLATHPDTQKKLQEEIDRALPNKAPPTYDTVMEMEYLDMVLNE 363 Query: 1220 TLRLYPAGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARFSD 1399 TLRLYP G + R+ +++++ GV +PKG + IP +H DP+ W P+ +EF P RFS Sbjct: 364 TLRLYPIGNRLERVCKKDVEINGVFMPKGSVVMIPSYALHRDPQHW-PEPEEFRPERFSK 422 Query: 1400 ARP---QLHSYLPFGAGARTCLGQGFA 1471 + YLPFG G R C+G FA Sbjct: 423 ENKGSIDPYVYLPFGNGPRNCIGMRFA 449
>Q99N16:CP4F3_MOUSE Cytochrome P450 4F3 - Mus musculus (Mouse)| Length = 524 Score = 121 bits (303), Expect = 1e-26 Identities = 100/382 (26%), Positives = 174/382 (45%), Gaps = 27/382 (7%) Frame = +2 Query: 416 LHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRGILKSNGEAWAHQRKIIAPEFFLD 595 + + P ++ + L +L K + +P G G+L S G+ W+ R+++ P F + Sbjct: 99 IRIFHPAFIKPVVLAPALVAPKDTVFYRFLKPWLGDGLLMSTGDKWSRHRRMLTPAFHFN 158 Query: 596 KVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAYSADVISRTCF---GSSYV 766 +K V + DS + W+ K G+ + + + I + D + + F + Sbjct: 159 ILKPYVKVFNDSTNIMHAKWQRLASK--GSAYLNMFEHISLMTLDSLQKCVFSFDSNCQE 216 Query: 767 KGKKIFLKLRELQKAVSKPNV-LAEMTGLRFFPTKKNRQAWGLHKQVH-----------R 910 K + + EL V++ + L L ++ T + + VH R Sbjct: 217 KPSEYITAILELSALVARRHQRLLLHVDLFYYLTHDGMRFRKACRLVHDFTDAVIRERRR 276 Query: 911 LIL-----EIVKESGEDKNLLRAILHSASSSKVGLGEAENFIVDNCKSIYFAGYESTAVT 1075 +L +++K + K L + S + G ++ I + F G+++TA Sbjct: 277 TLLDQGGDDVLKAKAKAKTLDFIDVLLLSKDEHGKALSDEDIRAEADTFMFGGHDTTASG 336 Query: 1076 AAWCLMLLGLHPEWQDRVRQEVLEVCGGR---PLDSQSLQKMKNLTMVIQETLRLYPAGA 1246 +W L L HPE+Q+R RQEV E+ R ++ L ++ LTM I+E+LRL+P Sbjct: 337 LSWILYNLARHPEYQERCRQEVRELLRDREPEEIEWDDLAQLPFLTMCIKESLRLHPPVT 396 Query: 1247 FVSRMALQELKL-GGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARFSDARPQLHS- 1420 +SR Q++ L G IPKGV I + H +P +W PD + ++P RF + S Sbjct: 397 AISRCCTQDIVLPDGRVIPKGVISRISIFGTHHNPAVW-PDPEVYDPFRFDADNVKGRSP 455 Query: 1421 --YLPFGAGARTCLGQGFATAE 1480 ++PF AG R C+GQ FA +E Sbjct: 456 LAFIPFSAGPRNCIGQTFAMSE 477
>P78329:CP4F2_HUMAN Cytochrome P450 4F2 - Homo sapiens (Human)| Length = 520 Score = 121 bits (303), Expect = 1e-26 Identities = 104/401 (25%), Positives = 178/401 (44%), Gaps = 35/401 (8%) Frame = +2 Query: 383 VFTYSMGNVVF-------LHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRGILKSN 541 V TY G V+ L + PD++R + + K + + EP G G+L S Sbjct: 81 VATYPQGFKVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLSA 140 Query: 542 GEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAY 721 G+ W+ R+++ P F + +K + + +S + W+ + +D+ + I Sbjct: 141 GDKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMF--EHISLM 198 Query: 722 SADVISRTCFGSS---YVKGKKIFLKLRELQKAVSKPN--VLAEMTGLRFFPTKKNRQAW 886 + D + + F K + + EL VSK + +L + L ++ T ++ Sbjct: 199 TLDSLQKCVFSFDSHCQEKPSEYIAAILELSALVSKRHHEILLHIDFL-YYLTPDGQRFR 257 Query: 887 GLHKQVHRLILEIVKE----------------SGEDKNLLRAILHSASSSKVGLGEAENF 1018 + VH +++E + K L + S + G ++ Sbjct: 258 RACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDED 317 Query: 1019 IVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGR---PLDSQSLQK 1189 I + F G+++TA +W L L HPE+Q+R RQEV E+ R ++ L Sbjct: 318 IRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAH 377 Query: 1190 MKNLTMVIQETLRLYPAGAFVSRMALQELKL-GGVHIPKGVNIYIPVSTMHLDPKLWGPD 1366 + LTM ++E+LRL+P +SR Q++ L G IPKG+ I V H +P +W PD Sbjct: 378 LPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIICLISVFGTHHNPAVW-PD 436 Query: 1367 AKEFNPARFSDARPQLHS---YLPFGAGARTCLGQGFATAE 1480 + ++P RF + S ++PF AG R C+GQ FA AE Sbjct: 437 PEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAE 477
>Q9Y6A2:CP46A_HUMAN Cytochrome P450 46A1 - Homo sapiens (Human)| Length = 500 Score = 120 bits (302), Expect = 1e-26 Identities = 108/410 (26%), Positives = 192/410 (46%), Gaps = 19/410 (4%) Frame = +2 Query: 362 WRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATH---EPLFGRGIL 532 W K++GPV ++ + + V+ P+ V+ + + Y E LFG+G++ Sbjct: 67 WAKKYGPVVRVNVFHKTSVIVTSPESVKKFLMSTKYNKDSKMYRALQTVFGERLFGQGLV 126 Query: 533 KS-NGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDD 709 N E W QR++I F + +++ + A+ L+E EA+ D G + + D Sbjct: 127 SECNYERWHKQRRVIDLAFSRSSLVSLMETFNEKAEQLVEILEAKAD---GQTPVSMQDM 183 Query: 710 IRAYSADVISRTCFG--SSYVKGKKIFLKLRELQKAVSKPNVLAEMTGLRFFPTKKN--- 874 + + D++++ FG +S + G + L + K + + + T +F P K+ Sbjct: 184 LTYTAMDILAKAAFGMETSMLLGAQ--KPLSQAVKLMLEGITASRNTLAKFLPGKRKQLR 241 Query: 875 --RQAWGLHKQVHRLILEIVKES---GED--KNLLRAILHSASSSKVGLGEAENFIVDNC 1033 R++ +QV R ++ +E+ GE+ ++L IL + ++ G +NF+ Sbjct: 242 EVRESIRFLRQVGRDWVQRRREALKRGEEVPADILTQILKAEEGAQDDEGLLDNFV---- 297 Query: 1034 KSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGG-RPLDSQSLQKMKNLTMV 1210 + + AG+E++A A+ +M L PE R++ EV EV G R LD + L +++ L+ V Sbjct: 298 -TFFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVIGSKRYLDFEDLGRLQYLSQV 356 Query: 1211 IQETLRLYPAGAFVSRMALQELKLGGVHIPKGVNIYIPVSTM-HLDPKLWGPDAKEFNPA 1387 ++E+LRLYP R+ +E + GV +P + M +D + D FNP Sbjct: 357 LKESLRLYPPAWGTFRLLEEETLIDGVRVPGNTPLLFSTYVMGRMD--TYFEDPLTFNPD 414 Query: 1388 RFSDARPQ-LHSYLPFGAGARTCLGQGFATAEXXXXXXXXXXXFALRLSP 1534 RF P+ +Y PF G R+C+GQ FA E RL P Sbjct: 415 RFGPGAPKPRFTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQRLEFRLVP 464
>Q9VGB3:CP133_DROME Probable cytochrome P450 313a3 - Drosophila melanogaster (Fruit fly)| Length = 492 Score = 120 bits (302), Expect = 1e-26 Identities = 109/389 (28%), Positives = 164/389 (42%), Gaps = 22/389 (5%) Frame = +2 Query: 359 KWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRGILKS 538 K+ +G +G F+ P + +I L L +SS G G+L Sbjct: 60 KYMDIYGSTCLVWVGPTPFVITRDPKIAEEIFLSPEC-LNRSSIFSKPVNSCTGDGLLSL 118 Query: 539 NGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRA 718 W +RK + P F + + + + A+TL+ A +D G + K+ DDI Sbjct: 119 EASKWVDRRKNLNPAFKQNVLLSFLPIFNSEAKTLV----AFLDSLVGQGEKKVRDDIVR 174 Query: 719 YSADVISRTCFGSSYVKGKKI----FLKLRELQKAVSKPNVLAEMTGLRFFPT------K 868 +S + ++T G+ K LK E + NVL T + F T + Sbjct: 175 WSFRIATQTTVGTDVKKDASFKNDSVLKSYETFMKIIVMNVLLPFTHNKIFSTLGGFETQ 234 Query: 869 KNRQAWGLHKQVHRLI---LEIVKESGEDKNLLRAILHSASSSKVGLGEAENFIVDNCKS 1039 K ++K + ++ L ESG + I + + G E + C S Sbjct: 235 KALAKSNVNKMIGTIVDKKLMTKPESGSQPEITSVINKAIELHRNGEMSREE-VQSECCS 293 Query: 1040 IYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLE---VCGGRPLDSQSLQKMKNLTMV 1210 A +E+T T L+LL + PE QD V QE+ E V G + LQ+M L V Sbjct: 294 FVVAAFETTGDTVYHALILLAMFPEHQDTVYQELKELFPVAGDFEVTYDDLQRMVFLERV 353 Query: 1211 IQETLRLYPAGAFVSRMALQELKLG-GVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPA 1387 + ETLRL P+ F R +++ +L GV IPKGV I I + H + WG D FNP Sbjct: 354 VNETLRLIPSVPFTPRETIRDFRLSSGVVIPKGVGIGIDIFATHRNRDHWGTDPSSFNPD 413 Query: 1388 RF-----SDARPQLHSYLPFGAGARTCLG 1459 F D P ++Y+PF G R C+G Sbjct: 414 HFLPDNVRDRHP--YAYIPFSKGRRNCIG 440
>Q3MID2:CP4F3_RAT Cytochrome P450 4F3 - Rattus norvegicus (Rat)| Length = 524 Score = 120 bits (301), Expect = 2e-26 Identities = 102/382 (26%), Positives = 171/382 (44%), Gaps = 27/382 (7%) Frame = +2 Query: 416 LHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRGILKSNGEAWAHQRKIIAPEFFLD 595 + + P ++ + L + K P G G+L S G+ W+ R+++ P F + Sbjct: 99 IRIFHPAFIKPVILAPASVAPKDRVFYRFLRPWLGDGLLLSTGDKWSRHRRMLTPAFHFN 158 Query: 596 KVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAYSADVISRTCF---GSSYV 766 +K V + DS + W+ S G+ + + + I + D + + F + Sbjct: 159 ILKPYVKIFNDSTNIMHAKWQRLA--SQGSARLDMFEHISLMTLDSLQKCVFSFDSNCQE 216 Query: 767 KGKKIFLKLRELQKAVSKPN-VLAEMTGLRFFPTKKNRQAWGLHKQVHRLILEIVKE--- 934 K + + EL V++ + L L + T+ + + VH +++E Sbjct: 217 KPSEYITAILELSALVARRHQSLLLHVDLFYHLTRDGMRFRKACRLVHDFTDAVIRERRC 276 Query: 935 -----SGEDKNLLRA------ILHSASSSKVGLGEA--ENFIVDNCKSIYFAGYESTAVT 1075 G+D +A + SK GEA + I + F G+++TA Sbjct: 277 TLPDQGGDDALKAKAKAKTLDFIDVLLLSKDEHGEALSDEDIRAEADTFMFGGHDTTASG 336 Query: 1076 AAWCLMLLGLHPEWQDRVRQEVLEVCGGR---PLDSQSLQKMKNLTMVIQETLRLYPAGA 1246 +W L L HPE+Q+R RQEV E+ R ++ L ++ LTM I+E+LRL+P Sbjct: 337 LSWILYNLAKHPEYQERCRQEVRELLRDREPEEIEWDDLAQLPFLTMCIKESLRLHPPAT 396 Query: 1247 FVSRMALQELKL-GGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARFSDARPQLHS- 1420 +SR Q++ L G IPKGV I + H +P +W PD + +NP RF + S Sbjct: 397 AISRCCTQDIMLPDGRVIPKGVICRISIFGTHHNPAVW-PDPEVYNPFRFDADNGKGRSP 455 Query: 1421 --YLPFGAGARTCLGQGFATAE 1480 ++PF AG R C+GQ FA +E Sbjct: 456 LAFIPFSAGPRNCIGQTFAMSE 477
>Q27519:C13A7_CAEEL Putative cytochrome P450 CYP13A7 - Caenorhabditis elegans| Length = 518 Score = 120 bits (301), Expect = 2e-26 Identities = 103/436 (23%), Positives = 191/436 (43%), Gaps = 48/436 (11%) Frame = +2 Query: 317 IVHDY----RPAVLPFYEKWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKS 484 ++H + P L F E W K++GPV+ + G L +S P+ V ++ + + Sbjct: 42 VIHKFTNYENPGALKFSE-WTKKYGPVYGITEGVEKTLVISDPEFVHEVFVKQFDNFYGR 100 Query: 485 SYLKATHEPLFGRGI--LKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWE 658 +P + + + + G W R + +P F ++ ++ + +S L+ E Sbjct: 101 KLTAIQGDPNKNKRVPLVAAQGHRWKRLRTLASPTFSNKSLRKIMGTVEESVTELVRSLE 160 Query: 659 ARVDKSGGTVDIKIDDDIRAYSADVISRTCFG--SSYVKGKKIFLKLRELQK-------- 808 + G T+D+ + + ++ D+I + G S + + K++ + K Sbjct: 161 -KASAEGKTLDML--EYYQEFTMDIIGKMAMGQEKSLMFRNPMLDKVKTIFKEGRNNVFM 217 Query: 809 --------AVSKPNVLAEMTGLRFFPTKKNRQAWGLHKQVHRLILEI---VKESGEDKNL 955 ++ N+ A+ L+ ++ L+K++ + + ++ SGE ++ Sbjct: 218 ISGIFPFVGIALRNIFAKFPSLQMATDIQSILEKALNKRLEQREADEKAGIEPSGEPQDF 277 Query: 956 LRAILHSASSSKVGLGEAE-----------------NFIVDNCKSIYFAGYESTAVTAAW 1084 + L + S+ GEAE + I+ AGY++TA++ ++ Sbjct: 278 IDLFLDARSTVDFFEGEAEQDFAKSEVLKVDKHLTFDEIIGQLFVFLLAGYDTTALSLSY 337 Query: 1085 CLMLLGLHPEWQDRVRQEVLEVCGGRPLDSQSLQKMKNLTMVIQETLRLYPAGAFV-SRM 1261 LL HPE Q ++++EV C + L K+K L V++E LRLYP + V +R Sbjct: 338 SSYLLATHPEIQKKLQEEVDRECPDPEVTFDQLSKLKYLECVVKEALRLYPLASLVHNRK 397 Query: 1262 ALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARFSDARPQLHS---YLPF 1432 L+ + G+ I G NI + ++H DPK+WG D EF P R+ + YLPF Sbjct: 398 CLKTTNVLGMEIEAGTNINVDTWSLHHDPKVWGDDVNEFKPERWESGDELFFAKGGYLPF 457 Query: 1433 GAGARTCLGQGFATAE 1480 G G R C+G A E Sbjct: 458 GMGPRICIGMRLAMME 473
>Q27518:C13A2_CAEEL Putative cytochrome P450 CYP13A2 - Caenorhabditis elegans| Length = 515 Score = 118 bits (296), Expect = 7e-26 Identities = 113/412 (27%), Positives = 184/412 (44%), Gaps = 38/412 (9%) Frame = +2 Query: 359 KWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDL--GKSSYLKATHEPLFGRGIL 532 +W K++G V+ Y+ G L V+ P +V +I + + K + ++ E +L Sbjct: 61 EWTKKYGKVYGYTDGTQRTLVVADPAMVHEIFVKQFDNFYGRKLNPIQGNPEKEQRVHLL 120 Query: 533 KSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDI 712 + G W R I + F +K M + DSA LL E + + G I + Sbjct: 121 AAQGYRWKRLRTISSQSFSNASLKKMKRTVEDSALELLRHIEKQ---TAGGEQIDMLRFY 177 Query: 713 RAYSADVISRTCFGS--SYVKGKKIFLKLRELQKAVSK---------PNVLAEMTGLRF- 856 + Y+ DVI R G S + I +RE+ K P + + L F Sbjct: 178 QEYTMDVIGRFAMGQTDSMMFKNPIVNVVREIFCGSRKNLMLICQVFPPIGQFIRDLTFK 237 Query: 857 FPTKKNRQAWGLHKQVHRLIL-----EIVKESGEDKNLLRAILHSASSSKVGLGEA-ENF 1018 FP + + + + V + E ESGE ++ + L + S EA E+F Sbjct: 238 FPRIPAFKLYSIMQDVVAARIAQREREKGAESGEPQDFIDLFLDARSDDVDFSAEAREDF 297 Query: 1019 ---------------IVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVC 1153 +V C G+++TA++ ++ LL ++P+ Q++V +E+ Sbjct: 298 SKRNLKITKELSADEVVGQCFLFLIGGFDTTALSLSYVTYLLAVNPKIQEKVIEEIAREF 357 Query: 1154 GGRPLDSQSLQKMKNLTMVIQETLRLYP-AGAFVSRMALQELKLGGVHIPKGVNIYIPVS 1330 G ++ + L ++K + VI+E LRLYP A SR ++ + GV I GV + + Sbjct: 358 GTSEVEFEKLGRLKYMDCVIKEALRLYPLASISNSRKCMKTTTVNGVKIEAGVYVQMDTW 417 Query: 1331 TMHLDPKLWGPDAKEFNPARFSDARPQLH--SYLPFGAGARTCLGQGFATAE 1480 ++H DP+LWG D KEF P R+S P H +YLPFG G R C+G A E Sbjct: 418 SLHYDPELWGEDVKEFKPERWSTDEPLEHKGAYLPFGLGPRQCIGMRLAIME 469
>P33274:CP4F1_RAT Cytochrome P450 4F1 - Rattus norvegicus (Rat)| Length = 524 Score = 118 bits (295), Expect = 9e-26 Identities = 107/406 (26%), Positives = 179/406 (44%), Gaps = 40/406 (9%) Frame = +2 Query: 383 VFTYSMGNVVFLHVSRP-------DVVRDINLCVSLDLGKSSYLKATHEPLFGRGILKSN 541 V TY G ++++ P D+VR I + K +P G G+L S Sbjct: 81 VGTYPQGFLMWIGPMVPVITLCHSDIVRSILNASAAVALKDVIFYTILKPWLGDGLLVSA 140 Query: 542 GEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAY 721 G+ W+ R+++ P F + +K V + DS + W+ + + +D+ + + Sbjct: 141 GDKWSRHRRMLTPAFHFNILKPYVKIFNDSTNIMHAKWKRLISEGSSRLDMF--EHVSLM 198 Query: 722 SADVISRTCFG---SSYVKGKKIFLKLRELQKAVSKPNVLAEMTGLRFFPTKKNRQAWGL 892 + D + + F + K + + EL V+K + L F N G+ Sbjct: 199 TLDSLQKCVFSFDSNCQEKSSEYIAAILELSALVAKRH----QQPLLFMDLLYNLTPDGM 254 Query: 893 --HKQ---VHRLILEIVKESGE---DKNLLRAILHSASSSKV-------------GLGEA 1009 HK VH +++E D+ L + A S + G + Sbjct: 255 RFHKACNLVHEFTDAVIRERRRTLPDQGLDEFLKSKAKSKTLDFIDVLLLTKDEDGKELS 314 Query: 1010 ENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGR---PLDSQS 1180 + I + F G+++TA +W L L PE+Q+R RQEV E+ R ++ Sbjct: 315 DEDIRAEADTFMFEGHDTTASGLSWILYNLANDPEYQERCRQEVQELLRDRDPEEIEWDD 374 Query: 1181 LQKMKNLTMVIQETLRLYPAGAFVSRMALQELKL-GGVHIPKGVNIYIPVSTMHLDPKLW 1357 L ++ LTM I+E+LRL+P +SR Q++ L G IPKG+ I + +H +P +W Sbjct: 375 LAQLPFLTMCIKESLRLHPPVTVISRCCTQDILLPDGRTIPKGIICLISIFGIHHNPSVW 434 Query: 1358 GPDAKEFNPARF-----SDARPQLHSYLPFGAGARTCLGQGFATAE 1480 PD + +NP RF D+ P +++PF AG R C+GQ FA +E Sbjct: 435 -PDPEVYNPFRFDPENIKDSSPL--AFIPFSAGPRNCIGQTFAMSE 477
>Q64481:CP3AG_MOUSE Cytochrome P450 3A16 - Mus musculus (Mouse)| Length = 504 Score = 118 bits (295), Expect = 9e-26 Identities = 117/464 (25%), Positives = 202/464 (43%), Gaps = 40/464 (8%) Frame = +2 Query: 200 FRRQGIGGPRPSFPYGNMADXXXXXXXXXXXXXXXXXXXIVHDYRPAVLPFYEKWRKEHG 379 F++QGI GP+P P+ V +Y + F + +++G Sbjct: 33 FKKQGIPGPKP-LPF----------------------LGTVLNYYKGLWKFDMECYEKYG 69 Query: 380 PVFTYSMGNVVFLHVSRPDVVRDINL--CVSLDLGKSSYLKATHEPLFGRGILKSNGEAW 553 + G + ++ P+ ++++ + C S+ + + + + I + E W Sbjct: 70 KTWGLFDGQIPLFVITDPETIKNVLVKECFSVFTNRQDFFPVG---IMSKSISLAKDEEW 126 Query: 554 AHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAYSADV 733 R +++P F +K M ++ L++ +K G V +K D + AYS DV Sbjct: 127 KRYRALLSPTFTSGNLKEMFPVIEQYGDILVKYLRQEAEK-GKPVAVK--DVLGAYSMDV 183 Query: 734 ISRTCFGSS----------YVKGKKIFLKLR---ELQKAVSKPNVLA---EMTGLRFFPT 865 I T FG + +V+ K L+ L +V+ L EM + FP Sbjct: 184 IISTTFGVNIDSLNNPEDPFVENAKKVLRFDYFDPLSLSVALFPFLTPIYEMLNICMFPK 243 Query: 866 K-------------KNRQAWGLHKQVHR-----LILEIVKESGEDKNLLRAILHSASSSK 991 +NR KQ HR L++E +S +DK+ +A+ Sbjct: 244 DSIEFFKKFVDRMTENRLD---SKQKHRVDFIYLMMEAYNKS-KDKDSHKAL-------- 291 Query: 992 VGLGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGR-PL 1168 +E I FAGYE+T+ ++ + L HP+ Q ++++E+ E + P Sbjct: 292 -----SEIEITAQSIIFIFAGYETTSSILSFTVYSLATHPDIQKKLQEEIDEALPNKAPP 346 Query: 1169 DSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDP 1348 ++ M+ L MV+ ETLRLYP + R+ +++++ G++IPKG + IP +H DP Sbjct: 347 TYDTVMAMEYLDMVLNETLRLYPITNRLQRVCKKDVEINGIYIPKGSTVIIPSYVLHHDP 406 Query: 1349 KLWGPDAKEFNPARFSDARP---QLHSYLPFGAGARTCLGQGFA 1471 + W P+ +EF P RFS + YLPFG G R C+G FA Sbjct: 407 QHW-PEPEEFQPERFSKENKGSIDPYVYLPFGNGPRNCIGMRFA 449
>Q9VG40:CP134_DROME Probable cytochrome P450 313a4 - Drosophila melanogaster (Fruit fly)| Length = 478 Score = 118 bits (295), Expect = 9e-26 Identities = 109/406 (26%), Positives = 180/406 (44%), Gaps = 26/406 (6%) Frame = +2 Query: 332 RPAVLPFYEKWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINL---CVSLDLGKSSYLKAT 502 R +L + + +HGP +G + F+ VS P VV+DI CV+ K KA Sbjct: 50 REDILNAFGCFLDKHGPTIFSWLGPIPFMIVSDPQVVQDIFTSPHCVN----KGIIYKAV 105 Query: 503 HEPLFGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGG 682 + G G+ W+ RK++ P F + + + LL+ E D Sbjct: 106 DDGA-GVGLFSLKDPRWSIHRKLLNPAFGHKVLLSFLPIFNRETALLLDQLEPLQDDG-- 162 Query: 683 TVDIKIDDDIRAYSADVISRTCFGSSYVKGKKIFLKLREL---------QKAVSKPNVLA 835 + + +++++ + ++T GS VK ++ F L Q A + + Sbjct: 163 --EKDLIPLLQSFTLGIATQTTMGSD-VKDEESFRSNSLLGRYQCRFCRQLAGKESHYYQ 219 Query: 836 EMTGLRFFPTKKNRQAWGLHKQVHRLILE-----IVKESGEDKNLLRAILHSASSSKVGL 1000 T +R F + K + R + E + DKNL ++ + G+ Sbjct: 220 AKTEIRQF----------IRKIIERKLAEDEMGALPSIQSNDKNLFLNLV--TDLMRRGV 267 Query: 1001 GEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEV---CGGRPLD 1171 +N + D I F +E+TA + LMLL + PE+Q+R +E+ + G + Sbjct: 268 FTLKN-VEDESNIIVFGAFETTANAVYYTLMLLAMFPEYQERAFEEIKTIFPNTGDFDVS 326 Query: 1172 SQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKLG-GVHIPKGVNIYIPVSTMHLDP 1348 Q+M L +++ E++R+ P VSR Q+LKL G+ +PKGV I I + MH Sbjct: 327 YADTQQMVYLDLILNESMRVIPPVPVVSRQTSQDLKLSNGIVVPKGVQIAIDIYHMHRSK 386 Query: 1349 KLWGPDAKEFNPARF-----SDARPQLHSYLPFGAGARTCLGQGFA 1471 K+WGPDA+ FNP F D P ++Y+PF G R C+G +A Sbjct: 387 KIWGPDAETFNPDHFLPHNIQDKHP--YAYIPFTKGIRNCIGWRYA 430
>Q09653:C13AA_CAEEL Putative cytochrome P450 CYP13A10 - Caenorhabditis elegans| Length = 519 Score = 117 bits (294), Expect = 1e-25 Identities = 109/423 (25%), Positives = 180/423 (42%), Gaps = 50/423 (11%) Frame = +2 Query: 362 WRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDL--GKSSYLKATHEPLFGRGILK 535 W K +GP++ Y+ G + L VS D+VR I + + K + ++ E + Sbjct: 60 WTKLYGPIYGYTEGTIKTLIVSDIDIVRQIFVEQYDNFYGRKLNPIQGDPEKDERTNLFS 119 Query: 536 SNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIR 715 + G W R I +P F + ++ + + DSA LL E + + G +D+ + Sbjct: 120 AQGFRWKRLRAISSPTFSNNSLRKINVTVEDSAMELLRHIEEQTSE-GQQIDML--QFYQ 176 Query: 716 AYSADVISRTCFGSSYVKGKKIFLK-LRELQKAVSKPN------------VLAEMTGLRF 856 ++ D I R G + ++F L + +A+ N LA++ RF Sbjct: 177 EFTMDTIGRIAMGQT---DSQMFKNPLLKFVRAIFGDNRKHIPLIGGVFPTLAQV--FRF 231 Query: 857 FPTKKNRQAWGLHKQVHRLILEIVK--------------ESGEDKNLLRAILH------- 973 F K V++ ++ V+ E GE ++ + L Sbjct: 232 FMLKFPLLGAANFIHVNKTVVTAVQNRIDQRENDRKNGIEIGEPQDFIDLFLEARADDVE 291 Query: 974 ---------SASSSKVGLGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDR 1126 S +SS IV C AG+++TA++ ++ LL HPE Q + Sbjct: 292 HFQENNGDFSKTSSYGNRQLTTQEIVGQCLVFLIAGFDTTALSLSYTTFLLATHPEVQKK 351 Query: 1127 VRQEVLEVCGGRPLDSQSLQKMKNLTMVIQETLRLYPAGAFV-SRMALQELKLGGVHIPK 1303 +++E+ C + L K+K + +I+ETLRLYP G SR ++ KLG V + Sbjct: 352 LQEEIERECIEPSISFDHLSKLKYMDCIIKETLRLYPLGTMANSRRCMRATKLGNVEVEV 411 Query: 1304 GVNIYIPVSTMHLDPKLWGPDAKEFNPARFSDARP----QLHSYLPFGAGARTCLGQGFA 1471 G + + ++H D K+WG DAKEF P R+ D Q Y+ FG G R C+G A Sbjct: 412 GTMVQVDTWSLHTDTKIWGDDAKEFKPERWLDPNCDQVFQKGGYISFGLGPRQCVGMRLA 471 Query: 1472 TAE 1480 E Sbjct: 472 YME 474
>Q9WVK8:CP46A_MOUSE Cytochrome P450 46A1 - Mus musculus (Mouse)| Length = 500 Score = 117 bits (293), Expect = 2e-25 Identities = 106/410 (25%), Positives = 191/410 (46%), Gaps = 19/410 (4%) Frame = +2 Query: 362 WRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATH---EPLFGRGIL 532 W K++GPV ++ + V+ P+ V+ + + Y E LFG+G++ Sbjct: 67 WAKKYGPVVRVNVFYKTSVIVTSPESVKKFLMSTKYNKDSKMYRALQTVFGERLFGQGLV 126 Query: 533 KS-NGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDD 709 + W QRK++ F + +++ + A+ L+E EA+ D G + + D Sbjct: 127 SECDYGRWYKQRKVMDLAFSRSSLVSLMETFNEKAEQLVEILEAKAD---GQTPVSMQDM 183 Query: 710 IRAYSADVISRTCFG--SSYVKGKKIFLKLRELQKAVSKPNVLAEMTGLRFFPTKKN--- 874 + + D++++ FG +S + G + L + K + + + T +F P K+ Sbjct: 184 LTCATIDILAKAAFGMETSMLLGAQ--KPLSQAVKVMLEGISASRNTLAKFMPGKRKQLR 241 Query: 875 --RQAWGLHKQVHRLILEIVKES---GEDK--NLLRAILHSASSSKVGLGEAENFIVDNC 1033 R++ L +QV + ++ +E+ GED ++L IL + + + + ++DN Sbjct: 242 EIRESIRLLRQVGKDWVQRRREALKRGEDMPADILTQILKAEEGA-----QDDEVLLDNF 296 Query: 1034 KSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGG-RPLDSQSLQKMKNLTMV 1210 + + AG+E++A A+ +M L PE R++ EV EV G R LD + L +++ L+ V Sbjct: 297 VTFFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVVGSKRHLDYEDLGRLQYLSQV 356 Query: 1211 IQETLRLYPAGAFVSRMALQELKLGGVHIPKGVNIYIPVSTM-HLDPKLWGPDAKEFNPA 1387 ++E+LRLYP R+ +E + GV +P + M +D + D FNP Sbjct: 357 LKESLRLYPPAWGTFRLLEEETLIDGVRVPGNTPLLFSTYVMGRMD--TYFEDPLTFNPD 414 Query: 1388 RFSDARPQ-LHSYLPFGAGARTCLGQGFATAEXXXXXXXXXXXFALRLSP 1534 RF P+ +Y PF G R+C+GQ FA E RL P Sbjct: 415 RFGPGAPKPRFTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQRIEFRLVP 464
>O42563:CP3AR_ONCMY Cytochrome P450 3A27 - Oncorhynchus mykiss (Rainbow trout) (Salmo| gairdneri) Length = 518 Score = 117 bits (293), Expect = 2e-25 Identities = 94/343 (27%), Positives = 154/343 (44%), Gaps = 34/343 (9%) Frame = +2 Query: 545 EAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAYS 724 + W R +++P F ++K M +M + TLL + + DK T+++K + YS Sbjct: 125 DTWRRIRSVLSPSFTSGRLKEMFGIMKQHSSTLLSGMKKQADKDQ-TIEVK--EFFGPYS 181 Query: 725 ADVISRTCFG----------SSYVKGKKIFLKLRELQKAVSKPNVLAEMTG-------LR 853 DV++ T F +V K LK +L + L TG Sbjct: 182 MDVVTSTAFSVDIDSLNNPSDPFVSNVKKMLKF-DLFNPLFLLVALFPFTGPILEKMKFS 240 Query: 854 FFPT-------------KKNRQAWGLHKQVHRLILEIVKESGEDKNLLRAILHSASSSKV 994 FFPT K R +V L L I + G D + Sbjct: 241 FFPTAVTDFFYASLAKIKSGRDTGNSTNRVDFLQLMIDSQKGSDTK-------TGEEQTK 293 Query: 995 GLGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGR-PLD 1171 GL + E I+ FAGYE+++ T ++ L + ++++E+ V + P+ Sbjct: 294 GLTDHE--ILSQAMIFIFAGYETSSSTMSFLAYNLATNHHVMTKLQEEIDTVFPNKAPIQ 351 Query: 1172 SQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPK 1351 ++L +M L V+ E+LRLYP + R+A + +++ G+ IPK + +P T+H DP+ Sbjct: 352 YEALMQMDYLDCVLNESLRLYPIAPRLERVAKKTVEINGIVIPKDCIVLVPTWTLHRDPE 411 Query: 1352 LWGPDAKEFNPARFSDARPQL---HSYLPFGAGARTCLGQGFA 1471 +W D +EF P RFS + ++Y+PFGAG R C+G FA Sbjct: 412 IWS-DPEEFKPERFSKENKESIDPYTYMPFGAGPRNCIGMRFA 453
>Q27517:C13A3_CAEEL Putative cytochrome P450 CYP13A3 - Caenorhabditis elegans| Length = 520 Score = 117 bits (292), Expect = 2e-25 Identities = 110/428 (25%), Positives = 189/428 (44%), Gaps = 55/428 (12%) Frame = +2 Query: 362 WRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRG----- 526 W KE+GP++ ++ G L VS P+ V ++ D ++ PL G Sbjct: 60 WTKEYGPMYGFTDGVEKTLVVSDPEFVHEV-FVKQFD----NFYARKQNPLQGDPDKDPR 114 Query: 527 --ILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKI 700 ++ S G W R + +P F ++ + + +S ++ E + G T+DI Sbjct: 115 IHLVTSQGHRWKRLRTLASPTFSNKSLRKIFSTVEESVAEMMRHLE-KGTAGGKTIDIL- 172 Query: 701 DDDIRAYSADVISRTCFGSSYVKGKKIFL-----KLRELQKAVSKPNVLAEMTGL----- 850 + + ++ D+I + G S G +F K+R + ++ N++ + G+ Sbjct: 173 -EYYQEFTMDIIGKIAMGQS---GSMMFENPWLDKIRAIFN--TRGNIIFIICGIVPFTG 226 Query: 851 ---RFFPTKKNRQAWGLHKQVHRLILEIVKE--------------SGEDKNLLRAILHSA 979 R+F +K A + +H L + + K SGE ++ + L Sbjct: 227 SIFRWFFSKVPT-AQTVTSLMHTLEIALTKRVEQRAADEKAGIESSGEPQDFIDLFLDVQ 285 Query: 980 SSS-----KVGLGEAENFIVDNCKSIYF------------AGYESTAVTAAWCLMLLGLH 1108 + + + G A + IV K + F AGY++TA++ ++ LL H Sbjct: 286 ADTDFLEDETKNGFARSQIVKVDKHLTFDEIIGQLFVFLLAGYDTTALSLSYSSYLLARH 345 Query: 1109 PEWQDRVRQEVLEVCGGRPLDSQSLQKMKNLTMVIQETLRLYPAGAFV-SRMALQELKLG 1285 PE Q ++++EV C + L K+K + VI+ETLRLYP + V +R ++ + Sbjct: 346 PEIQKKLQEEVDRECPDPEVTFDQLSKLKYMECVIKETLRLYPLASIVHNRKCMKSTTVL 405 Query: 1286 GVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARFSDARPQL---HSYLPFGAGARTCL 1456 G+ I +G N+ T+H DPK WG +A EF P R+ Q +YLPFG G R C+ Sbjct: 406 GMKIEEGTNVQADTWTLHYDPKFWGENANEFKPERWESGDEQAVAKGAYLPFGLGPRICI 465 Query: 1457 GQGFATAE 1480 G A E Sbjct: 466 GMRLAYME 473
>P15128:CP4B1_RABIT Cytochrome P450 4B1 - Oryctolagus cuniculus (Rabbit)| Length = 506 Score = 116 bits (291), Expect = 3e-25 Identities = 104/391 (26%), Positives = 171/391 (43%), Gaps = 30/391 (7%) Frame = +2 Query: 518 GRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIK 697 G+G+L +G W RK++ P F D +K V + DS + +LE WE + + G + DI Sbjct: 118 GKGLLVLDGPKWFQHRKLLTPGFHYDVLKPYVAIFADSTRIMLEKWEKKACE-GKSFDIF 176 Query: 698 IDDDIRAYSADVISRTCFG-----------SSYVKGKKIFLKLRELQKAVSKPNVLAEMT 844 D+ + D + + FG S YV ++ L +++ + N Sbjct: 177 --SDVGHMALDTLMKCTFGKGDSGLNHRDSSYYVAVSELTLLMQQRIDSFQYHNDFIYWL 234 Query: 845 ---GLRFFPTKKNRQAWGLHKQVHRLI------LEIVKESGEDKN-----LLRAILHSAS 982 G RF R H R+I L+ KE + +N L +L Sbjct: 235 TPHGRRFL-----RACRAAHDHTDRVIRQRKAALQDEKEREKIQNRRHLDFLDILLDVRG 289 Query: 983 SSKVGLGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGR 1162 S V L + + + + F G+++T +W L + L+PE Q R R+EV E+ G + Sbjct: 290 ESGVQLSDTD--LRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQQRCREEVREILGDQ 347 Query: 1163 -PLDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELK-LGGVHIPKGVNIYIPVSTM 1336 + L KM LTM ++E RLYP V R + + + G +P G I + + + Sbjct: 348 DSFQWEDLAKMTYLTMCMKECFRLYPPVPQVYRQLSKPVSFVDGRSLPAGSLISLHIYAL 407 Query: 1337 HLDPKLWGPDAKEFNPARFS---DARPQLHSYLPFGAGARTCLGQGFATAEXXXXXXXXX 1507 H + +W PD + F+P RFS + ++++PF AG R C+GQ FA E Sbjct: 408 HRNSDVW-PDPEVFDPLRFSPENSSGRHPYAFIPFSAGPRNCIGQQFAMNEMKVVTALCL 466 Query: 1508 XXFALRLSPLYQHSPALKLIVEPEFGVDITL 1600 F + PL +L++ + G+ + L Sbjct: 467 LRFEFSVDPLRLPIKLPQLVLRSKNGIHLYL 497
>Q08477:CP4F3_HUMAN Cytochrome P450 4F3 - Homo sapiens (Human)| Length = 520 Score = 116 bits (290), Expect = 3e-25 Identities = 98/383 (25%), Positives = 172/383 (44%), Gaps = 28/383 (7%) Frame = +2 Query: 416 LHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRGILKSNGEAWAHQRKIIAPEFFLD 595 + + P ++ + + + K + +P G G+L S GE W+ R+++ P F + Sbjct: 99 VRIFHPTYIKPVLFAPAAIVPKDKVFYSFLKPWLGDGLLLSAGEKWSRHRRMLTPAFHFN 158 Query: 596 KVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAYSADVISRTCFGSS---YV 766 +K + + +S + W+ S G+ + + + I + D + + F Sbjct: 159 ILKPYMKIFNESVNIMHAKWQLLA--SEGSARLDMFEHISLMTLDSLQKCVFSFDSHCQE 216 Query: 767 KGKKIFLKLRELQKAVSKPN--VLAEMTGLRFFPTKKNRQAWGLHKQVHRLILEIVKE-- 934 K + + EL V+K + +L + L ++ T ++ + VH +++E Sbjct: 217 KPSEYIAAILELSALVTKRHQQILLYIDFL-YYLTPDGQRFRRACRLVHDFTDAVIQERR 275 Query: 935 --------------SGEDKNLLRAILHSASSSKVGLGEAENFIVDNCKSIYFAGYESTAV 1072 + K L + S + G ++ I + F G+++TA Sbjct: 276 RTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTAS 335 Query: 1073 TAAWCLMLLGLHPEWQDRVRQEVLEVCGGR---PLDSQSLQKMKNLTMVIQETLRLYPAG 1243 +W L L HPE+Q+R RQEV E+ R ++ L ++ LTM I+E+LRL+P Sbjct: 336 GLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPV 395 Query: 1244 AFVSRMALQELKL-GGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARFSDARPQLHS 1420 VSR Q++ L G IPKG+ I V H +P +W PD + ++P RF + S Sbjct: 396 PAVSRCCTQDIVLPDGRVIPKGIICLISVFGTHHNPAVW-PDPEVYDPFRFDPKNIKERS 454 Query: 1421 ---YLPFGAGARTCLGQGFATAE 1480 ++PF AG R C+GQ FA AE Sbjct: 455 PLAFIPFSAGPRNCIGQAFAMAE 477
>P58048:C71B8_ARATH Cytochrome P450 71B8 - Arabidopsis thaliana (Mouse-ear cress)| Length = 506 Score = 115 bits (288), Expect = 6e-25 Identities = 102/400 (25%), Positives = 180/400 (45%), Gaps = 31/400 (7%) Frame = +2 Query: 353 YEKWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRGI- 529 + K EHGPV G V + +S + + + S DL S K LF R Sbjct: 54 FHKLSLEHGPVMLLRFGVVPMVVISSKEAAKQV--LKSRDLETCSRPKLVANGLFTRNFK 111 Query: 530 ---LKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKI 700 GE W +K++ E F K + + LL ++ ++ VD++ Sbjct: 112 DIAFAQYGEDWREMKKLVGLELFNPKKHKFFRYIREEEGDLLVKKLSKSSQTQTLVDLR- 170 Query: 701 DDDIRAYSADVISRTCFGSSYVKGKKIFLKLRELQKAV--SKPNVLAEMTGLRFFPTKKN 874 +++A +I R FG ++ + F+ + L++ V S+ NV + FFPT Sbjct: 171 -KAFFSFTAGIIFRVSFGQNFRECD--FIDMDRLEELVQESETNVFS-FAFTDFFPTGLG 226 Query: 875 ---RQAWGLHKQVHRLILEIVK-------------ESGEDKNLLRAILHSAS-SSKVGLG 1003 + G H ++ + ++ K +S + NL+ ++L + S++ G Sbjct: 227 WLVDRISGQHSRIEKAFSKLTKFFQHVIDEELKIGQSQDHSNLVSSMLDMINRSTEYGSF 286 Query: 1004 E-AENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGRP--LDS 1174 + + ++ I G + +T W + L HP ++R+E+ G + Sbjct: 287 KITSDHLIAMMTDIVLGGVNAGTITMIWTMTELTRHPRVMKKLREEIRATLGPNKERITE 346 Query: 1175 QSLQKMKNLTMVIQETLRLYPAGAFV-SRMALQELKLGGVHIPKGVNIYIPVSTMHLDPK 1351 + L+K++ L +VI+ET RL+P G F+ R + ++++ G HIPK +I I + DPK Sbjct: 347 EDLEKVEYLKLVIKETFRLHPPGPFLLPRQVMSDIEIQGYHIPKNAHIKISTYAIGRDPK 406 Query: 1352 LWGPDAKEFNPARFSDA----RPQLHSYLPFGAGARTCLG 1459 W + +EFNP RF++ + Q + LPFGAG R+C G Sbjct: 407 CW-TNPEEFNPERFANTSINYKGQHYELLPFGAGRRSCPG 445
>Q9VFJ0:CP131_DROME Probable cytochrome P450 313a1 - Drosophila melanogaster (Fruit fly)| Length = 492 Score = 115 bits (287), Expect = 8e-25 Identities = 117/437 (26%), Positives = 182/437 (41%), Gaps = 37/437 (8%) Frame = +2 Query: 344 LPFYEKWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGR 523 L F K+ ++G MG V F+ P VV DI KS ++ G Sbjct: 55 LSFRTKYLNKYGSTILTWMGPVPFIVTRDPKVVEDIFSSPDCH-NKSQHIVNAITSCMGN 113 Query: 524 GILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKID 703 G+L W +RK P F D + + + L+ + VDK +I + Sbjct: 114 GLLGKQDPHWLDRRKHFNPSFKQDLLLSFFHIFDAETKVLMNLLDTYVDKG----EIDVV 169 Query: 704 DDIRAYSADVISRTCFGSSYVKGKKIFLKLRELQKAVSKPNVLAEMTGLRFFPTKKNRQA 883 ++ +S + ++T GS VK + F + S ++++ T P +NR Sbjct: 170 PEMLRWSFKIAAQTTMGSE-VKHDEHF---KNGSLVESFESLISHSTLNILMPLVQNRM- 224 Query: 884 WGLHKQVHRLILEIVKESGEDK------NLLRAILHSASSSKVGL-----GEAENFIVDN 1030 I K G DK + ++ +L + + KV + E+ IV N Sbjct: 225 -------------ISKICGYDKLRADNFSRIQKMLDNVVNKKVNPLPKTDSDPESNIVIN 271 Query: 1031 -------------------CKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEV- 1150 C + AGY+++A+T L LL HPE Q+ V +E+ V Sbjct: 272 RAMELYRKGDITYMDVKSECCIMIAAGYDTSALTVYHALFLLANHPEHQEAVFEELNGVF 331 Query: 1151 --CGGRPLDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKLG-GVHIPKGVNIYI 1321 G + +QK+ L VI+ETLRL PA +R +++L GV IPKGV I I Sbjct: 332 PDAGHFGITYPDMQKLDYLERVIKETLRLIPAIPITARETKNDVRLSNGVLIPKGVVIGI 391 Query: 1322 PVSTMHLDPKLWGPDAKEFNPARF-SDARPQLH--SYLPFGAGARTCLGQGFATAEXXXX 1492 + H +P++WGPDA FNP F ++ Q H +Y+PF G R C+G +A Sbjct: 392 DMFHTHRNPEVWGPDADNFNPDNFLAENMEQKHPYAYIPFARGKRNCIGSKYAMMSSKFA 451 Query: 1493 XXXXXXXFALRLSPLYQ 1543 + + S LY+ Sbjct: 452 LCRILRNYKISTSTLYK 468
>P51870:CP4F5_RAT Cytochrome P450 4F5 - Rattus norvegicus (Rat)| Length = 526 Score = 114 bits (285), Expect = 1e-24 Identities = 97/362 (26%), Positives = 161/362 (44%), Gaps = 37/362 (10%) Frame = +2 Query: 506 EPLFGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGT 685 +P G G+ S+G+ W+ R+++ P F D +K V + S + W+ + G+ Sbjct: 129 KPWLGDGLFLSSGDKWSRHRRLLTPAFHFDILKPYVKIFNQSVNIMHAKWKHLCLE--GS 186 Query: 686 VDIKIDDDIRAYSADVISRTCFG---------SSYVKGKKIFLKLRELQKAVSKPNVLAE 838 +++ ++I + D + + FG S Y+ L+L L + + L Sbjct: 187 ARLEMFENISLMTLDSLQKCLFGFDSNCQESPSEYISA---ILELSSL--IIKRSQQLFL 241 Query: 839 MTGLRFFPTKKNRQAWGLHKQVHRLILEIVKESGEDKNLLRA-----ILHSASSSKV--- 994 ++ T R+ VH +++E + LL + L S + SK Sbjct: 242 YLDFLYYRTADGRRFRKACDLVHNFTDAVIRER---RRLLSSQGTDEFLESKTKSKSKTL 298 Query: 995 -------------GLGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQ 1135 G ++ I + F G+++TA +W L L HPE+Q+R RQ Sbjct: 299 DFIDVLLLAKDEHGKELSDEDIRAEADTFMFGGHDTTASALSWILYNLARHPEYQERCRQ 358 Query: 1136 EVLEVCGGR---PLDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKL-GGVHIPK 1303 EV E+ R ++ L ++ LTM I+E+LRL+P + R Q++ L G IPK Sbjct: 359 EVWELLRDREPEEIEWDDLAQLPFLTMCIKESLRLHPPAIDLLRRCTQDIVLPDGRVIPK 418 Query: 1304 GVNIYIPVSTMHLDPKLWGPDAKEFNPARFSDARPQLH---SYLPFGAGARTCLGQGFAT 1474 G I + +H +P +W PD + F+P RF Q S++PF AG R C+GQ FA Sbjct: 419 GNICVISIFGIHHNPSVW-PDPEVFDPFRFDSENRQKRSPLSFIPFSAGPRNCIGQTFAM 477 Query: 1475 AE 1480 E Sbjct: 478 NE 479
>Q964T2:CP9E2_BLAGE Cytochrome P450 9e2 - Blattella germanica (German cockroach)| Length = 533 Score = 114 bits (284), Expect = 2e-24 Identities = 91/370 (24%), Positives = 167/370 (45%), Gaps = 45/370 (12%) Frame = +2 Query: 506 EPLFGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLE------------ 649 EP+FG+ + G W R ++P F K+K M L+ + + L E Sbjct: 117 EPMFGKNLFNLRGHRWKEMRSTLSPAFTSSKMKNMFVLVSECGKQLGEFLMECSRDKNKK 176 Query: 650 PWEARVDKSGGTVDIKIDDDIRAYSADVISRTCFGSSYVKGKKIFLKLRELQKAVSKPNV 829 ++++ G + +++ D Y+ DVI+ + FG K + ++ K V+ Sbjct: 177 TEGCKIEREGDLLTVELKDLYTRYTNDVIATSAFGIGCDSLKNPKNEFFQMGKDVTNFGG 236 Query: 830 LAEMTGLRFFPTKKNRQAWGLH------KQVHRLILEIVKESGEDKNLLRA-ILHSASSS 988 + + L + + + + L + R ++ ++ + K ++R ++H + Sbjct: 237 IRQFIFLGYLFSPRLMKYLNLKFLSSKATEFFRFLVHNTMDTRKTKGIIRPDMIHLLMQA 296 Query: 989 KVGL------GEAENFIVDNCK-----------SIYFAGYESTAVTAAWCLMLLGLHPEW 1117 K G GE I K +FAG+++ + + LL +P+ Sbjct: 297 KEGTLKSEENGETNGKIASKPKWDDDDLTAQAVLFFFAGFDTASTLLCFMSHLLATNPDV 356 Query: 1118 QDRVRQEV---LEVCGGRPLDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKL-- 1282 Q+R++ E+ LE G+ L +++ MK L MV+ E+LRLYP F R ++ +L Sbjct: 357 QNRLQDEIDQSLEENDGK-LTYEAIHSMKYLDMVVSESLRLYPPAIFTDRKCVKNYRLPM 415 Query: 1283 -GGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARFSDARP---QLHSYLPFGAGART 1450 + G ++IP+ +H DPK + P+ ++F+P RFSD + +YLPFG+G R Sbjct: 416 EPSYTLEPGDAVWIPIYAIHHDPKYY-PNPEKFDPERFSDENKDNIKPFTYLPFGSGPRN 474 Query: 1451 CLGQGFATAE 1480 C+G FA E Sbjct: 475 CIGNRFALME 484
>Q9V4T5:CP4E1_DROME Probable cytochrome P450 4e1 - Drosophila melanogaster (Fruit fly)| Length = 531 Score = 113 bits (283), Expect = 2e-24 Identities = 98/406 (24%), Positives = 173/406 (42%), Gaps = 29/406 (7%) Frame = +2 Query: 350 FYEKWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRGI 529 F+ W + F Y +G + V+ P + I +L + KS TH P G G+ Sbjct: 59 FFGWWHEYGKDNFRYWIGYYSNIMVTNPKYMEFILSSQTL-ISKSDVYDLTH-PWLGLGL 116 Query: 530 LKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDD 709 L S G W RK+I P F + ++ ++M +++ ++ + D GG + ++ Sbjct: 117 LTSTGSKWHKHRKMITPAFHFNILQDFHEVMNENSTKFIDQLKKVAD--GGNI-FDFQEE 173 Query: 710 IRAYSADVISRTCFGSSYVKGKKIFLKLRELQKAVSKPNVLAEMTGLRFFPTKKNRQAWG 889 + DVI T G S ++ R + ++ + F P K+N+ + Sbjct: 174 AHYLTLDVICDTAMGVSINA-----MENRSSSVVQAFKDITYTIKMRAFSPWKRNKYLFH 228 Query: 890 LHKQ------------------------VHRLILEIVKESGEDKNLLRAILHSASSSKV- 994 + V + LE+ ++ E A L + SSKV Sbjct: 229 FAPEYPEYSKTLKTLQDFTNEIIAKRIEVRKSGLEVGIKADEFSRKKMAFLDTLLSSKVD 288 Query: 995 GLGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCG----GR 1162 G + + + F G+++T + + LL HP+ Q+++ E +V G GR Sbjct: 289 GRPLTSQELYEEVSTFMFEGHDTTTSGVGFAVYLLSRHPDEQEKLFNEQCDVMGASGLGR 348 Query: 1163 PLDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHL 1342 Q + MK+L + I+E RLYP+ F+ R ++ + G +PKG + + + + Sbjct: 349 DATFQEISTMKHLDLFIKEAQRLYPSVPFIGRFTEKDYVIDGDIVPKGTTLNLGLLMLGY 408 Query: 1343 DPKLWGPDAKEFNPARFSDARPQLHSYLPFGAGARTCLGQGFATAE 1480 + +++ D +F P RF +P Y+PF AG R C+GQ FA E Sbjct: 409 NDRVF-KDPHKFQPERFDREKPGPFEYVPFSAGPRNCIGQKFALLE 453
>O17624:C13B1_CAEEL Putative cytochrome P450 cyp-13B1 - Caenorhabditis elegans| Length = 527 Score = 112 bits (281), Expect = 4e-24 Identities = 124/505 (24%), Positives = 202/505 (40%), Gaps = 54/505 (10%) Frame = +2 Query: 128 VGACSLALYLYYTVWVVPQRLLAGFRRQGIGGPRPSFPYGNMADXXXXXXXXXXXXXXXX 307 +GA + + L+ T+ + + +RR+GI GP GN D Sbjct: 1 MGAIIVLVVLFATIAGYFKWIHTYWRRRGISGPEGLPFIGNYYDLADVNKPRGY------ 54 Query: 308 XXXIVHDYRPAVLPFYEKWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSS 487 ++H KW ++ G VF Y G V L VS D+++++ L + Sbjct: 55 ---LIH-----------KWTQKFGKVFGYYEGAVPVLVVSDMDMLQEL----FLKKFDNF 96 Query: 488 YLKATHEPLFGR----------GILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQ 637 Y + + + G + S G W R + +P F + +K + D+M DSA Sbjct: 97 YARKSTNHIHGNLECSKSEPRINLFTSRGARWKRLRALASPGFSVKALKQVHDVMEDSAI 156 Query: 638 TLLEPWEARVDKSGGTVDIKIDDDIRAYSADVISRTCFG---------SSYVKGKKIFLK 790 +++ D I + ++ DVISR G S K IF++ Sbjct: 157 NMVDLMAKHEDGK----PFNIHAYFQEFTYDVISRLAMGQPNSELFNNSGVEIVKSIFMR 212 Query: 791 LRELQK---AVSKPNVLAEMTGLRFFPTKKNRQAWGLHKQVHRLILEIVKESGEDKNLLR 961 + V P E R F Q + K +L I K++ E + Sbjct: 213 THRVLPWYFTVLFPQF--EHLVKRMFYNHAAVQGGDIEK-----LLLICKKTVESR---- 261 Query: 962 AILHSASSSKVGLGEAENFIVDNCKSIY------------------------------FA 1051 I ++K+G AEN +D + Y A Sbjct: 262 -IQEREENAKLGFENAENDFIDMFLNYYSEQVEDIEFGSTVEKKVTAEDVIGACFVFLLA 320 Query: 1052 GYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGRPLDSQSLQKMKNLTMVIQETLRL 1231 G+++TA + A+ LL HPE ++EV V G + + K+K L V++E+LRL Sbjct: 321 GFDTTANSLAYASYLLAKHPEKMKLAQEEVDTVVGSENVSYDDMTKLKYLDAVVRESLRL 380 Query: 1232 YPAGAFV-SRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARFSD-AR 1405 YP F SR ++ LG ++I KGV I V ++H ++WG +A +F P R+ + + Sbjct: 381 YPVAWFACSRECVKPTTLGDIYIDKGVKIEADVMSLHRSKEIWGENADDFVPERWLEPSS 440 Query: 1406 PQLHSYLPFGAGARTCLGQGFATAE 1480 S++PFGAG R C+G +E Sbjct: 441 RHTMSWIPFGAGPRQCVGMRLGLSE 465
>Q9V9L1:CP6W1_DROME Probable cytochrome P450 6w1 - Drosophila melanogaster (Fruit fly)| Length = 514 Score = 112 bits (280), Expect = 5e-24 Identities = 100/419 (23%), Positives = 185/419 (44%), Gaps = 41/419 (9%) Frame = +2 Query: 326 DYRPAVLPFYEKWRKEH-GPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKAT 502 ++ A +PF+E+ +K H P F V++ V+RD+ L ++ + K Y Sbjct: 44 EFLTAKVPFFEQIQKFHEAPGFENEPFVGVYMTHRPALVIRDLELIKTVMIKKFQYFNNR 103 Query: 503 ------HEPLFG-RGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEA 661 H G + + + W R I+P F K+K M LMV + L + E Sbjct: 104 VLQTDPHNDALGYKNLFFARSPGWRELRTKISPVFTSGKIKQMYPLMVKIGKNLQDSAE- 162 Query: 662 RVDKSGGTVDIKIDDDIRAYSADVISRTCFG----------SSYVKGKKIFLKLRELQKA 811 + G ++++ D ++ D+I+ FG S + + L L + Sbjct: 163 ---RLGSGTEVQVKDLCSRFTTDLIATIAFGVEANALQDAKSEFFYHNRAIFSLT-LSRG 218 Query: 812 VSKPNV-----LAEMTGLRFFPTKKNRQAWGLHKQVHRLILEIVKESGEDKNLLRAIL-- 970 + + LA + ++ F +R+ + +L+ + +GE +N L IL Sbjct: 219 IDFAIIFMIPALASLARVKLF----SRETTKFIRSSVNYVLKERERTGEKRNDLIDILLA 274 Query: 971 ----HSASSSKVGLGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQE 1138 +A+ K+ +++V AG+E++A T L L + QDR+RQE Sbjct: 275 LKREAAANPGKMSKEVDLDYLVAQAAVFQTAGFETSASTMTMTLYELAKNEALQDRLRQE 334 Query: 1139 VLEVCGGRP-LDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELK--------LGGV 1291 +++ G + + +Q+M L+ V+ ETLR YP ++ R Q + + Sbjct: 335 IVDFFGDEDHISYERIQEMPYLSQVVNETLRKYPIVGYIERECSQPAEGERFTLEPFHNM 394 Query: 1292 HIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARFSDARP---QLHSYLPFGAGARTCLG 1459 +P G++IY+ +H DP+ W PD ++++P RF+ + + +Y+PFG G R C+G Sbjct: 395 ELPHGMSIYMSTVAVHRDPQYW-PDPEKYDPERFNSSNRDNLNMDAYMPFGVGPRNCIG 452
>P77900:CP132_MYCTU Putative cytochrome P450 132 - Mycobacterium tuberculosis| Length = 461 Score = 111 bits (278), Expect = 8e-24 Identities = 103/416 (24%), Positives = 178/416 (42%), Gaps = 22/416 (5%) Frame = +2 Query: 413 FLHVSRPDVVRDINLCVSLDLGKSSYLKATH----EPLFGRGILKSNGEAWAHQRKIIAP 580 F+ +S PD V + L + Y+K+ G +L G++WA R + Sbjct: 56 FVSISHPDYVDHV-----LHEARLKYVKSDEYGPIRATAGLNLLTDEGDSWARHRGALNS 110 Query: 581 EFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAYSADVISRTCFGSS 760 F ++G+V LM+D + + ARV + + + + A+ + FG Sbjct: 111 TFARRHLRGLVGLMIDP---IADVTAARVPGAQFDMHQSMVETTLRVVANALFSQDFGPL 167 Query: 761 Y-------VKGKKIFLKLREL------QKAVSKPNVLAEMTGLRFFPTKKNRQ--AWGLH 895 +G + KL L + V + +G+ P + Q L Sbjct: 168 VQSMHDLATRGLRRAEKLERLGLWGLMPRTVYDTLIWCIYSGVHLPPPLREMQEITLTLD 227 Query: 896 KQVHRLILEIVKESGEDKNLLRAILHSASSSKVGLGEAENFIVDNCKSIYFAGYESTAVT 1075 + ++ +I + E +LL +L S+ G+ + + D + AG+E+TA Sbjct: 228 RAINSVIDRRLAEPTNSADLLNVLL----SADGGIWPRQR-VRDEALTFMLAGHETTANA 282 Query: 1076 AAWCLMLLGLHPEWQDRVRQEVLEVCGGRPLDSQSLQKMKNLTMVIQETLRLYPAGAFVS 1255 +W L+ L+P+ +D + E+ +V G R + L K+ T +QE+ R + + ++ Sbjct: 283 MSWFWYLMALNPQARDHMLTELDDVLGMRRPTADDLGKLAWTTACLQESQRYFSSVWIIA 342 Query: 1256 RMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARF---SDARPQLHSYL 1426 R A+ + + G I +G + IP+ +H DP+ W PD F+P RF RP+ +YL Sbjct: 343 REAVDDDIIDGHRIRRGTTVVIPIHHIHHDPR-WWPDPDRFDPGRFLRCPTDRPRC-AYL 400 Query: 1427 PFGAGARTCLGQGFATAEXXXXXXXXXXXFALRLSPLYQHSPALKLIVEPEFGVDI 1594 PFG G R C+GQ FA E F L+P Y L + P+ GV + Sbjct: 401 PFGGGRRICIGQSFALMEMVLMAAIMSQHFTFDLAPGYHVELEATLTLRPKHGVHV 456
>O23365:C97B3_ARATH Cytochrome P450 97B3 - Arabidopsis thaliana (Mouse-ear cress)| Length = 580 Score = 111 bits (278), Expect = 8e-24 Identities = 102/447 (22%), Positives = 187/447 (41%), Gaps = 64/447 (14%) Frame = +2 Query: 332 RPAVLPFYEKWRKEHGPVFTYSMGNVVFLHVSRPDVVRDI--NLCVSLDLGKSSYLKATH 505 +P L Y+ W EHG ++ + G F+ +S P + R + S D G L Sbjct: 97 KPLFLSLYD-WFLEHGGIYKLAFGPKAFVVISDPIIARHVLRENAFSYDKG---VLAEIL 152 Query: 506 EPLFGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARV---DKS 676 EP+ G+G++ ++ + W +R+ I P F ++ MV + D ++ ++ E + + S Sbjct: 153 EPIMGKGLIPADLDTWKLRRRAITPAFHKLYLEAMVKVFSDCSEKMILKSEKLIREKETS 212 Query: 677 GG--TVDIKIDDDIRAYSADVISRTCFGSSYVKGKKIFLKLRELQKAVSKPNVLAEMTGL 850 G T+++ ++ + + + D+I + F + K + KAV AE Sbjct: 213 SGEDTIELDLEAEFSSLALDIIGLSVFNYDFGS----VTKESPVIKAVYGTLFEAEHRST 268 Query: 851 RFFP----------TKKNRQAWGLHKQVHRLILEIVKESGEDK--------------NLL 958 +FP + R+ K ++ + +++ + E + NL Sbjct: 269 FYFPYWNFPPARWIVPRQRKFQSDLKIINDCLDGLIQNAKETRQETDVEKLQERDYTNLK 328 Query: 959 RAILHSASSSKVGLGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQE 1138 A L G+ + + D+ ++ AG+E+TA W + LL +PE + + E Sbjct: 329 DASLLRFLVDMRGVDIDDRQLRDDLMTMLIAGHETTAAVLTWAVFLLSQNPEKIRKAQAE 388 Query: 1139 VLEVCGGRPLDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKLGGVH-------- 1294 + V G P +S++K++ + +++ E LRL+P + R L+ L G H Sbjct: 389 IDAVLGQGPPTYESMKKLEYIRLIVVEVLRLFPQPPLLIRRTLKPETLPGGHKGEKEGHK 448 Query: 1295 IPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARFSDARPQL-------------------- 1414 +PKG +I+I V +H P W + +F P RF + Sbjct: 449 VPKGTDIFISVYNLHRSPYFWD-NPHDFEPERFLRTKESNGIEGWAGFDPSRSPGALYPN 507 Query: 1415 -----HSYLPFGAGARTCLGQGFATAE 1480 ++LPFG G R C+G FA E Sbjct: 508 EIIADFAFLPFGGGPRKCIGDQFALME 534
>Q9VA27:CP4C3_DROME Cytochrome P450 4c3 - Drosophila melanogaster (Fruit fly)| Length = 535 Score = 110 bits (274), Expect = 2e-23 Identities = 97/422 (22%), Positives = 180/422 (42%), Gaps = 45/422 (10%) Frame = +2 Query: 473 LGKSSYLKATHE-----PLFGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQ 637 L ++ +H+ P G G+L S W +RKI+ P F + +D+ + + Sbjct: 120 LNSQKFVNKSHDYDYLHPWLGEGLLTSTDRKWHSRRKILTPAFHFKILDDFIDVFNEQSA 179 Query: 638 TLLEPWEARVDKSGGTVDIKIDDDIRAYSADVISRTCFG----------SSYVK---GKK 778 L V G+ + + + D++ T G S YVK G Sbjct: 180 VLARKLAVEV----GSEAFNLFPYVTLCTLDIVCETAMGRRIYAQSNSESEYVKAVYGIG 235 Query: 779 IFLKLRELQKAVSKPNVLAEMTGLRFFPTKKNRQAWGLHKQVHRLILE------IVKESG 940 ++ R+ + + + + + + N LH + +I E I++E+ Sbjct: 236 SIVQSRQAKIWLQSDFIFSLTAEYKLHQSYINT----LHGFSNMVIRERKAELAILQENN 291 Query: 941 EDKN--------------LLRAILHSASSSKVGLGEAENFIVDNCKSIYFAGYESTAVTA 1078 + N L + +SK G + I + + F G+++T+ Sbjct: 292 NNNNNNAPDAYDDVGKKKRLAFLDLLIDASKEGTVLSNEDIREEVDTFMFEGHDTTSAAI 351 Query: 1079 AWCLMLLGLHPEWQDRVRQEVLEVCGG---RPLDSQSLQKMKNLTMVIQETLRLYPAGAF 1249 +W L LLG HPE+Q+RV +E+ + G P ++L M+ L I+++LRL+P+ Sbjct: 352 SWTLFLLGCHPEYQERVVEELDSIFGDDKETPATMKNLMDMRYLECCIKDSLRLFPSVPM 411 Query: 1250 VSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARF---SDARPQLHS 1420 ++RM +++ +GG +P G I +H +P+++ P ++FNP F + A + Sbjct: 412 MARMVGEDVNIGGKIVPAGTQAIIMTYALHRNPRVF-PKPEQFNPDNFLPENCAGRHPFA 470 Query: 1421 YLPFGAGARTCLGQGFATAEXXXXXXXXXXXFALRLSPLYQHSPAL-KLIVEPEFGVDIT 1597 Y+PF AG R C+GQ FA E + + + L +LI+ P+ G+ + Sbjct: 471 YIPFSAGPRNCIGQKFAILEEKAVISTVLRKYKIEAVDRREDLTLLGELILRPKDGLRVK 530 Query: 1598 LT 1603 +T Sbjct: 531 IT 532
>Q9V3S0:CP4G1_DROME Cytochrome P450 4g1 - Drosophila melanogaster (Fruit fly)| Length = 556 Score = 109 bits (273), Expect = 3e-23 Identities = 110/429 (25%), Positives = 175/429 (40%), Gaps = 62/429 (14%) Frame = +2 Query: 371 EHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATH----EPLFGRGILKS 538 ++G +GNV+ + ++ P DI L +S G KA +P FG G+L S Sbjct: 90 KYGETMKAWLGNVLLVFLTNPS---DIELILS---GHQHLTKAEEYRYFKPWFGDGLLIS 143 Query: 539 NGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRA 718 NG W H RK+IAP F +K V VD ++ ++ KS + D + Sbjct: 144 NGHHWRHHRKMIAPTFHQSILKSFVPTFVDHSKAVVARMGLEAGKS-----FDVHDYMSQ 198 Query: 719 YSADVISRTCFGSSYV-KGKKIF------------------------------LKLRELQ 805 + D++ T G + +G K F KLRE Sbjct: 199 TTVDILLSTAMGVKKLPEGNKSFEYAQAVVDMCDIIHKRQVKLLYRLDSIYKFTKLRE-- 256 Query: 806 KAVSKPNVLAEMTGLRFFPTKKNRQAWGLHKQVHRLILEIVKESGEDKNLLRAILHSASS 985 K N++ MT K+N Q V + + K LR L Sbjct: 257 KGDRMMNIILGMTSKVVKDRKENFQEES-RAIVEEISTPVASTPASKKEGLRDDLDDIDE 315 Query: 986 SKVGLGEA-------------------ENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLH 1108 + VG E I+D +I F G+++T+ +++ L ++G+H Sbjct: 316 NDVGAKRRLALLDAMVEMAKNPDIEWNEKDIMDEVNTIMFEGHDTTSAGSSFALCMMGIH 375 Query: 1109 PEWQDRVRQEVLEVCGGRPLDSQSL---QKMKNLTMVIQETLRLYPAGAFVSRMALQELK 1279 + Q +V E + G L + +MK L VI ETLRLYP ++R +LK Sbjct: 376 KDIQAKVFAEQKAIFGDNMLRDCTFADTMEMKYLERVILETLRLYPPVPLIARRLDYDLK 435 Query: 1280 L--GGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARFSD---ARPQLHSYLPFGAGA 1444 L G +PKG + + +H P ++ P+ +F+P F A +S++PF AG Sbjct: 436 LASGPYTVPKGTTVIVLQYCVHRRPDIY-PNPTKFDPDNFLPERMANRHYYSFIPFSAGP 494 Query: 1445 RTCLGQGFA 1471 R+C+G+ +A Sbjct: 495 RSCVGRKYA 503
>P59954:CP132_MYCBO Putative cytochrome P450 132 - Mycobacterium bovis| Length = 461 Score = 109 bits (273), Expect = 3e-23 Identities = 104/423 (24%), Positives = 177/423 (41%), Gaps = 29/423 (6%) Frame = +2 Query: 413 FLHVSRPDVVRDINLCVSLDLGKSSYLKATH----EPLFGRGILKSNGEAWAHQRKIIAP 580 F+ +S PD V + L + Y+K+ G +L G++WA R + Sbjct: 56 FVSISHPDYVDHV-----LHEARLKYVKSDEYGPIRATAGLNLLTDEGDSWARHRGALNS 110 Query: 581 EFFLDKVKGMVDLMVD---SAQTLLEPWEARVDKSGGTVDIKIDDDIRAYSADVISRTCF 751 F ++G+V LM+D L P A+ D V+ + V++ F Sbjct: 111 TFARRHLRGLVGLMIDPIADVTAALVPG-AQFDMHQSMVETTLR---------VVANALF 160 Query: 752 GSSY-----------VKGKKIFLKLREL------QKAVSKPNVLAEMTGLRFFPTKKNRQ 880 + +G + KL L + V + +G+ P + Q Sbjct: 161 SQDFGPLVQSMHDLATRGLRRAEKLERLGLWGLMPRTVYDTLIWCIYSGVHLPPPLREMQ 220 Query: 881 --AWGLHKQVHRLILEIVKESGEDKNLLRAILHSASSSKVGLGEAENFIVDNCKSIYFAG 1054 L + ++ +I + E +LL +L S+ G+ + + D + AG Sbjct: 221 EITLTLDRAINSVIDRRLAEPTNSADLLNVLL----SADGGIWPRQR-VRDEALTFMLAG 275 Query: 1055 YESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGRPLDSQSLQKMKNLTMVIQETLRLY 1234 +E+TA +W L+ L+P+ +D + E+ +V G R + L K+ T +QE+ R + Sbjct: 276 HETTANAMSWFWYLMALNPQARDHMLTELDDVLGMRRPTADDLGKLAWTTACLQESQRYF 335 Query: 1235 PAGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARF---SDAR 1405 + ++R A+ + + G I +G + IP+ +H DP+ W PD F+P RF R Sbjct: 336 SSVWIIAREAVDDDIIDGHRIRRGTTVVIPIHHIHHDPR-WWPDPDRFDPGRFLRCPTDR 394 Query: 1406 PQLHSYLPFGAGARTCLGQGFATAEXXXXXXXXXXXFALRLSPLYQHSPALKLIVEPEFG 1585 P+ +YLPFG G R C+GQ FA E F L+P Y L + P+ G Sbjct: 395 PRC-AYLPFGGGRRICIGQSFALMEMVLMAAIMSQHFTFDLAPGYHVELEATLTLRPKHG 453 Query: 1586 VDI 1594 V + Sbjct: 454 VHV 456
>Q9V559:CP4P3_DROME Probable cytochrome P450 4p3 - Drosophila melanogaster (Fruit fly)| Length = 515 Score = 109 bits (272), Expect = 4e-23 Identities = 102/400 (25%), Positives = 177/400 (44%), Gaps = 37/400 (9%) Frame = +2 Query: 392 YSMGNVVFLHV---SRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRGILKSNGEAWAHQ 562 Y+MG ++ + S V+ D NL + K + H P G+L S G+ W + Sbjct: 87 YAMGTAIYNVIDADSAERVLNDPNL-----INKGTIYDFLH-PFLRTGLLTSTGKKWHAR 140 Query: 563 RKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAYSADVISR 742 RK+++P F + + ++ + + LE + K I +++ I ++ + I Sbjct: 141 RKMLSPTFHFNILNQFQEIFITESLKFLEQF-----KGNDEAIISLNEVIPRFTLNSICE 195 Query: 743 TCFG----SSYVKGKKIFLKLRELQ----KAVSKPNVLAEMTGLRFFPTKKNRQAWGLHK 898 T G KG + R+++ + +S P +L T + F K A + Sbjct: 196 TAMGVKLDEMAEKGDRYRENFRQIEECFIRRMSNP-LLWSDTLFKMFAEKDYASALDV-- 252 Query: 899 QVHRLILEIVKESGEDKN---------------LLRAILHSASSSKVGLGEAENF----- 1018 VH EI+ + + N L + A + L E + Sbjct: 253 -VHGFSSEIIAKRRDQLNDEIDSRGNTQTAEDELFTSKKRFAMLDTLILAEKDGLIDHIG 311 Query: 1019 IVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGG--RPLDSQSLQKM 1192 I + ++ F GY++T++ + LM + L+PE Q++ QE+ L+ L K+ Sbjct: 312 ICEEVDTLMFEGYDTTSIGLMFGLMNMSLYPEEQEKCYQEIQANIDDELNILNIGQLNKL 371 Query: 1193 KNLTMVIQETLRLYPAGAFVSRMALQELKL-GGVHIPKGVNIYIPVSTMHLDPKLWGPDA 1369 KNL I+ET+RL+P+ + R +E +L G+ +PKG I++ V +H +P+ W Sbjct: 372 KNLEYFIKETMRLFPSVPAMGRETTRETELSNGLILPKGSQIFVHVFDIHRNPEYW-DSP 430 Query: 1370 KEFNPARFSDARPQ---LHSYLPFGAGARTCLGQGFATAE 1480 +EF P RF Q ++Y+PF AG R C+GQ FA E Sbjct: 431 EEFRPERFLPENSQNRHTYAYIPFSAGQRNCIGQKFAMQE 470
>Q05JG2:ABAH1_ORYSJ Abscisic acid 8'-hydroxylase 1 - Oryza sativa subsp. japonica (Rice)| Length = 471 Score = 109 bits (272), Expect = 4e-23 Identities = 94/386 (24%), Positives = 172/386 (44%), Gaps = 9/386 (2%) Frame = +2 Query: 350 FYEKWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRGI 529 F+ K R ++GP+F + + VS P+ R + L L K ++ + L + I Sbjct: 64 FFNKKRNKYGPIFKTHILGCPCVMVSSPEAARFV-LVTQAHLFKPTFPASKERMLGPQAI 122 Query: 530 LKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDD 709 G+ AH R+I++ F + ++ V + A L W+ + + + Sbjct: 123 FFQQGDYHAHLRRIVSRAFSPESIRASVPAIEAIALRSLHSWDGQF--------VNTFQE 174 Query: 710 IRAYSADVISRTCFGSSYVKG----KKIFLKLRELQKAVSKPNVLAEMTGLRFFPTKKNR 877 ++ Y+ +V + FG ++ K+ +L L + ++ + G F K R Sbjct: 175 MKTYALNVALLSIFGEEEMRYIEELKQCYLTLEKGYNSMP-----VNLPGTLFHKAMKAR 229 Query: 878 QAWGLHKQVHRLILEIVKESGEDKNLLRAILHSASSSKVGLGEAENFIVDNCKSIYFAGY 1057 + G H + ++ G D +L S + L +A+ I DN + FA Sbjct: 230 KRLGAIV-AHIISARRERQRGND------LLGSFVDGREALTDAQ--IADNVIGVIFAAR 280 Query: 1058 ESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVC-----GGRPLDSQSLQKMKNLTMVIQET 1222 ++TA W + LG HP V +E L++ G PL ++MK + VIQET Sbjct: 281 DTTASVLTWMVKFLGDHPAVLKAVTEEQLQIAKEKEASGEPLSWADTRRMKMTSRVIQET 340 Query: 1223 LRLYPAGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARFSDA 1402 +R+ +F R A+++++ G IPKG + +H +P + P ++F+P+RF + Sbjct: 341 MRVASILSFTFREAVEDVEYQGYLIPKGWKVLPLFRNIHHNPDHF-PCPEKFDPSRF-EV 398 Query: 1403 RPQLHSYLPFGAGARTCLGQGFATAE 1480 P+ ++++PFG G +C G A E Sbjct: 399 APKPNTFMPFGNGTHSCPGNELAKLE 424
>Q09J79:ABAH1_ORYSI Abscisic acid 8'-hydroxylase 1 - Oryza sativa subsp. indica (Rice)| Length = 471 Score = 109 bits (272), Expect = 4e-23 Identities = 94/386 (24%), Positives = 172/386 (44%), Gaps = 9/386 (2%) Frame = +2 Query: 350 FYEKWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRGI 529 F+ K R ++GP+F + + VS P+ R + L L K ++ + L + I Sbjct: 64 FFNKKRNKYGPIFKTHILGCPCVMVSSPEAARFV-LVTQAHLFKPTFPASKERMLGPQAI 122 Query: 530 LKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDD 709 G+ AH R+I++ F + ++ V + A L W+ + + + Sbjct: 123 FFQQGDYHAHLRRIVSRAFSPESIRASVPAIEAIALRSLHSWDGQF--------VNTFQE 174 Query: 710 IRAYSADVISRTCFGSSYVKG----KKIFLKLRELQKAVSKPNVLAEMTGLRFFPTKKNR 877 ++ Y+ +V + FG ++ K+ +L L + ++ + G F K R Sbjct: 175 MKTYALNVALLSIFGEEEMRYIEELKQCYLTLEKGYNSMP-----VNLPGTLFHKAMKAR 229 Query: 878 QAWGLHKQVHRLILEIVKESGEDKNLLRAILHSASSSKVGLGEAENFIVDNCKSIYFAGY 1057 + G H + ++ G D +L S + L +A+ I DN + FA Sbjct: 230 KRLGAIV-AHIISARRERQRGND------LLGSFVDGREALTDAQ--IADNVIGVIFAAR 280 Query: 1058 ESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVC-----GGRPLDSQSLQKMKNLTMVIQET 1222 ++TA W + LG HP V +E L++ G PL ++MK + VIQET Sbjct: 281 DTTASVLTWMVKFLGDHPAVLKAVTEEQLQIAKEKEASGEPLSWADTRRMKMTSRVIQET 340 Query: 1223 LRLYPAGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARFSDA 1402 +R+ +F R A+++++ G IPKG + +H +P + P ++F+P+RF + Sbjct: 341 MRVASILSFTFREAVEDVEYQGYLIPKGWKVLPLFRNIHHNPDHF-PCPEKFDPSRF-EV 398 Query: 1403 RPQLHSYLPFGAGARTCLGQGFATAE 1480 P+ ++++PFG G +C G A E Sbjct: 399 APKPNTFMPFGNGTHSCPGNELAKLE 424
>Q964R1:CP6J1_BLAGE Cytochrome P450 6j1 - Blattella germanica (German cockroach)| Length = 501 Score = 108 bits (271), Expect = 5e-23 Identities = 95/341 (27%), Positives = 156/341 (45%), Gaps = 17/341 (4%) Frame = +2 Query: 509 PLFGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTV 688 PL I G+ W H R + P F K+K M L VD L + + K+ V Sbjct: 119 PLNANAIFALRGQKWKHVRTSLTPTFTTGKMKNMFYL-VDKCGQQLVLFIEKFAKAENPV 177 Query: 689 DIKIDDDIRAYSADVISRTCFG---SSYVKGKKIFLKLRELQKAVSKPNVLAEMTGLRFF 859 +K D + ++ DV + FG +S K F L +S + +A + F Sbjct: 178 AVK--DAVERFTMDVTAMCAFGIECNSLQDPKAEFSNLLHRIFQLSFTSAVANLATF-FA 234 Query: 860 PTKKNRQAWGL-HKQVHRLILEIV-------KESGEDKNLLRAILHSASSSKVGLGEAEN 1015 P +N L ++ I +IV +++GE +N L L +S+ + ++ Sbjct: 235 PWVQNFFRLKLMDSEIEDRIRDIVWRAVHLREKTGEKRNDLLDYLMELRTSETSKLDGDD 294 Query: 1016 FIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGG--RPLDSQSLQK 1189 F+ AG+ ++++T + L L +H + Q R E+ +V + + S++ Sbjct: 295 FVAQ-AFGFLVAGFHTSSMTLTFALYELSVHQDIQTTARTEIKDVLEHHKKKVTYYSIKD 353 Query: 1190 MKNLTMVIQETLRLYPAGAFVSRMALQELKL-GGVHIPKGVNIYIPVSTMHLDPKLWGPD 1366 MK L MV+ ETLR YPA F+ R ++ L + +P G +YIPV +H D K + P Sbjct: 354 MKYLDMVVNETLRKYPAIPFLDRRCQEDYPLTQDLMLPAGTGVYIPVYALHHDSKYF-PS 412 Query: 1367 AKEFNPARFSDARPQ---LHSYLPFGAGARTCLGQGFATAE 1480 +F+P RFS+ Q +Y+PFG G R C+G F + + Sbjct: 413 PAKFDPERFSEKNKQNIPHFAYMPFGEGPRNCIGMRFGSMQ 453
>O46051:C4D14_DROME Probable cytochrome P450 4d14 - Drosophila melanogaster (Fruit fly)| Length = 507 Score = 108 bits (271), Expect = 5e-23 Identities = 107/396 (27%), Positives = 170/396 (42%), Gaps = 35/396 (8%) Frame = +2 Query: 518 GRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIK 697 G G+L S G+ W +RKII P F ++ V++ + T++ + D++ G I Sbjct: 113 GDGLLISQGKKWFRRRKIITPAFHFKILEDFVEVFDQQSATMV---QKLYDRADGKTVIN 169 Query: 698 IDDDIRAYSADVISRTCFG--------SSYVKGKKIFLKLRELQKAVSKPNVLAEMTGLR 853 + + D+I+ T G + + + L + P + T Sbjct: 170 MFPVACLCAMDIIAETAMGVKINAQLQPQFTYVQSVTTASAMLAERFMNPLQRLDFTMKL 229 Query: 854 FFP---TKKNRQAWGLHKQVHRLILE-------IVKESGE-DKNLLR--------AILHS 976 F+P K N +H + +I E + + G+ D LL A+L Sbjct: 230 FYPKLLDKLNDAVKNMHDFTNSVITERRELLQKAIADGGDADAALLNDVGQKRRMALLDV 289 Query: 977 ASSSKV-GLGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVC 1153 S + G + + I + + F G+++T + A+ LL HPE Q RV QEV +V Sbjct: 290 LLKSTIDGAPLSNDDIREEVDTFMFEGHDTTTSSIAFTCYLLARHPEVQARVFQEVRDVI 349 Query: 1154 G---GRPLDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKLGGVHIPKGVNIYIP 1324 G P+ + L ++K L VI+E+LRL+P+ + R Q+ L G IP N+ I Sbjct: 350 GDDKSAPVTMKLLGELKYLECVIKESLRLFPSVPIIGRYISQDTVLDGKLIPADSNVIIL 409 Query: 1325 VSTMHLDPKLWGPDAKEFNPARFSDARP---QLHSYLPFGAGARTCLGQGFATAEXXXXX 1495 + DP + PD ++F P RFS R +Y PF AG R C+GQ FA E Sbjct: 410 IYHAQRDPDYF-PDPEKFIPDRFSMERKGEISPFAYTPFSAGPRNCIGQKFAMLEMKSTI 468 Query: 1496 XXXXXXFALRLSPLYQH-SPALKLIVEPEFGVDITL 1600 F L PL + P L +I+ G++ L Sbjct: 469 SKMVRHF--ELLPLGEEVQPVLNVILRSTTGINCGL 502
>Q2KIG5:THAS_BOVIN Thromboxane-A synthase - Bos taurus (Bovine)| Length = 533 Score = 108 bits (270), Expect = 7e-23 Identities = 103/419 (24%), Positives = 187/419 (44%), Gaps = 54/419 (12%) Frame = +2 Query: 365 RKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRGILKSNG 544 RK++GP+ Y +G ++F+ +S PD++ + + + +P+ +L Sbjct: 71 RKQYGPLSGYYLGRLMFIVISEPDMIEQVLVEKFSNFTNRMATGLEPKPV-ADSVLFLRD 129 Query: 545 EAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAYS 724 + W R ++ F +K+ M L+ + LL E R +SG DI+ Y+ Sbjct: 130 KRWEEVRSVLTVAFSPEKLSEMTPLISRACDVLLAHLE-RHAQSGEAFDIQ--RTYCCYT 186 Query: 725 ADVISRTCFGSS----------YVKGKKIF----LKLRELQKAVSKPNVLAEMTGLRFFP 862 DV++ FG+ +V+ + F + L +S P+++ + R P Sbjct: 187 TDVVASVAFGTEVNSQEAPEHPFVEHCRRFFASSIPKPLLVLLLSFPSIMVPLA--RILP 244 Query: 863 TKKNRQAWGLHKQVHRLILEIVKESGEDKN------LLRAILHSASSSKVGLGEA--ENF 1018 K + G ++ R ++ + + ++ +++ + HSA++ V + + F Sbjct: 245 NKNRDELNGFFNKLIRNVIALRDQQAAEERRRDFLQMVQDVRHSAATVGVEKFDIVRQVF 304 Query: 1019 IVDNCKS--------------------------IYFAGYESTAVTAAWCLMLLGLHPEWQ 1120 C + AGYE T ++ LL +PE Q Sbjct: 305 SATKCPANPPRRHSPRPLSKPLSVDEVVGQAFIFLIAGYEIVTNTLSFATYLLATNPECQ 364 Query: 1121 DRVRQEVLEVCGGRPLDSQ--SLQK-MKNLTMVIQETLRLYPAGAFVSRMALQELKLGGV 1291 +++ +EV + L + SLQ+ + L MVI+ETLR+YP +R+A Q+ ++ G Sbjct: 365 EKLLEEV-DCFSKEHLAPEYCSLQEGLPYLDMVIKETLRMYPPAFRFTRVAAQDCEVLGQ 423 Query: 1292 HIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARF---SDARPQLHSYLPFGAGARTCLG 1459 IP G + V +H DP+ W P+ + FNP RF + R + ++YLPFGAG R+CLG Sbjct: 424 RIPAGAVLETAVGALHYDPEHW-PNPENFNPERFTAEAQQRRRPYTYLPFGAGPRSCLG 481
>Q64462:CP4B1_MOUSE Cytochrome P450 4B1 - Mus musculus (Mouse)| Length = 511 Score = 108 bits (270), Expect = 7e-23 Identities = 104/428 (24%), Positives = 178/428 (41%), Gaps = 30/428 (7%) Frame = +2 Query: 407 VVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRGILKSNGEAWAHQRKIIAPEF 586 +VFL++ PD + + S K++Y+ G+G+L G W RK++ P F Sbjct: 89 IVFLNIYEPDYAKAV---YSRGDPKAAYVYDFFLQWIGKGLLVLEGPKWFQHRKLLTPGF 145 Query: 587 FLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAYSADVISRTCFG---- 754 D +K V + +S + +L+ WE + ++ I D+ + D + + FG Sbjct: 146 HYDVLKPYVAIFAESTRVMLDKWEKKASENKS---FDIFCDVGHMALDTLMKCTFGKGDS 202 Query: 755 -------SSYVKGKKIFLKLRELQKAVSKPNVLAEMT---GLRFFPTKKNRQAWGLHKQV 904 S Y+ + L +++ + N G RF R H Sbjct: 203 GLSHSDNSYYLAVSDLTLLMQQRIDSFQYHNDFIYWLTPHGRRFL-----RACQIAHDHT 257 Query: 905 HRLILE---IVKESGEDKNL--------LRAILHSASSSKVGLGEAENFIVDNCKSIYFA 1051 +I + +++ E K L L +L + S + L +A+ + + F Sbjct: 258 DHVIRQRKAALQDEKEQKKLQERRHLDFLDILLGARDESGIKLSDAD--LRAEVDTFMFE 315 Query: 1052 GYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGR-PLDSQSLQKMKNLTMVIQETLR 1228 G+++T +W L + L+P Q R R+EV E+ G R L +M LTM ++E R Sbjct: 316 GHDTTTSGISWFLYCMALYPMHQQRCREEVREILGDRDSFQWDDLAQMTYLTMCMKECFR 375 Query: 1229 LYPAGAFVSRMALQELK-LGGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARFSDAR 1405 LYP V R + + + G +P G I + + +H + +W PD + F+P RFS Sbjct: 376 LYPPVPQVYRQLSKPVTFVDGRSLPAGSLISLHIYALHRNSAVW-PDPEVFDPLRFSPEN 434 Query: 1406 ---PQLHSYLPFGAGARTCLGQGFATAEXXXXXXXXXXXFALRLSPLYQHSPALKLIVEP 1576 +++PF AG R C+GQ FA E F P +LI+ Sbjct: 435 MTGRHPFAFMPFSAGPRNCIGQQFAMNEMKVVTALCLLRFEFSPDPSKIPIKVPQLILRS 494 Query: 1577 EFGVDITL 1600 + G+ + L Sbjct: 495 KNGIHLYL 502
>O48921:C97B2_SOYBN Cytochrome P450 97B2 - Glycine max (Soybean)| Length = 576 Score = 108 bits (269), Expect = 9e-23 Identities = 112/448 (25%), Positives = 190/448 (42%), Gaps = 65/448 (14%) Frame = +2 Query: 332 RPAVLPFYEKWRKEHGPVFTYSMGNVVFLHVSRPDVVRDI--NLCVSLDLGKSSYLKATH 505 RP Y+ W EHG V+ + G F+ VS P V R I S D G L Sbjct: 92 RPLFFSLYD-WFLEHGAVYKLAFGPKAFVVVSDPIVARHILRENAFSYDKG---VLADIL 147 Query: 506 EPLFGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSG-- 679 EP+ G+G++ ++ + W +R++IAP F ++ MV + ++ + + ++ G Sbjct: 148 EPIMGKGLIPADLDTWKQRRRVIAPAFHNSYLEAMVKIFTTCSERTILKFNKLLEGEGYD 207 Query: 680 --GTVDIKIDDDIRAYSADVISRTCFGSSYVKGKKIFLKLRELQKAVSKPNVLAEMTGLR 853 ++++ ++ + + + D+I F + K + KAV AE Sbjct: 208 GPDSIELDLEAEFSSLALDIIGLGVFNYDFGS----VTKESPVIKAVYGTLFEAEHRSTF 263 Query: 854 FFPTKKNRQA-WGLHKQ----------------VHRLILEIVKESGEDKNLLRAILHSAS 982 + P K A W + +Q + R E +E+ +K R L+ Sbjct: 264 YIPYWKIPLARWIVPRQRKFQDDLKVINTCLDGLIRNAKESRQETDVEKLQQRDYLNLKD 323 Query: 983 SSKV-------GLGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEV 1141 +S + G + + D+ ++ AG+E+TA W + LL +P + + EV Sbjct: 324 ASLLRFLVDMRGADVDDRQLRDDLMTMLIAGHETTAAVLTWAVFLLAQNPSKMKKAQAEV 383 Query: 1142 LEVCG-GRPLDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKLGGVH-------- 1294 V G GRP +SL++++ + +++ E LRLYP + R +L+ L G H Sbjct: 384 DLVLGTGRPT-FESLKELQYIRLIVVEALRLYPQPPLLIRRSLKSDVLPGGHKGEKDGYA 442 Query: 1295 IPKGVNIYIPVSTMHLDPKLWG-PDAKEFNPARF-----------------SDARPQLH- 1417 IP G +++I V +H P W PD +F P RF S + L+ Sbjct: 443 IPAGTDVFISVYNLHRSPYFWDRPD--DFEPERFLVQNKNEEIEGWAGLDPSRSPGALYP 500 Query: 1418 -------SYLPFGAGARTCLGQGFATAE 1480 ++LPFG G R C+G FA E Sbjct: 501 NEVISDFAFLPFGGGPRKCVGDQFALME 528
>Q27698:CP6D1_MUSDO Cytochrome P450 6d1 - Musca domestica (House fly)| Length = 516 Score = 107 bits (267), Expect = 2e-22 Identities = 119/488 (24%), Positives = 200/488 (40%), Gaps = 48/488 (9%) Frame = +2 Query: 143 LALYLYYTVWVVPQRLLAGFRRQGIGGPRPSFPYGNMADXXXXXXXXXXXXXXXXXXXIV 322 L L + T+++ + + R G + + P G+MA + Sbjct: 5 LLLIVVTTLYIFAKLHYTKWERLGFESDKATIPLGSMAK-------------------VF 45 Query: 323 HDYRPAVLPFYEKWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLC---VSLDLG----K 481 H RP L + + K H V ++L +VRD L ++ D + Sbjct: 46 HKERPFGLVMSDIYDKCHEKVVG------IYLFFKPALLVRDAELARQILTTDFNSFHDR 99 Query: 482 SSYLKATHEPLFGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEA 661 Y+ ++P+ + G++W R +AP F K+KGM + + D A LL Sbjct: 100 GLYVDEKNDPM-SANLFVMEGQSWRTLRMKLAPSFSSGKLKGMFETVDDVAAKLLNHLNE 158 Query: 662 RVDKSGGTVDIKIDDDIRAYSADVISRTCFG---SSYVKGKKIFLKLRELQKAVSKPNVL 832 R+ K G + ++I + Y+ D+I FG S+ F L + K +L Sbjct: 159 RL-KDGQSHVLEIKSILTTYAVDIIGSVIFGLEIDSFTHPDNEFRVLSDRLFNPKKSTML 217 Query: 833 AEMTGLRFF---PTKKNRQAWGLHKQVHRLILEIVKESGE--------DKNLLRAILHSA 979 L F P K G + + +IVK + E K+LL+ + Sbjct: 218 QRFRNLSNFICPPLAKLLSRLGAKDPITYRLRDIVKRTIEFREEKGVVRKDLLQLFIQLR 277 Query: 980 SSSKVG----------LGEAEN-------FIVDNCKSIYFAGYESTAVTAAWCLMLLGLH 1108 ++ K+ AEN I N Y AG E+TA T ++ + L ++ Sbjct: 278 NTGKISDDNDKLWHDVESTAENLKAMSIDMIASNSFLFYIAGSETTAATTSFTIYELAMY 337 Query: 1109 PEWQDRVRQEV---LEVCGGRP---LDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQ 1270 PE + + EV L+ G +P L +++Q MK L + + ET R YP F++R Q Sbjct: 338 PEILKKAQSEVDECLQRHGLKPQGRLTYEAIQDMKYLDLCVMETTRKYPGLPFLNRKCTQ 397 Query: 1271 ELKLGG--VHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARFSDARPQLH--SYLPFGA 1438 + ++ + IPK I I + +H DP+ + P +++ P RF+D +Y+PFG Sbjct: 398 DFQVPDTKLTIPKETGIIISLLGIHRDPQYF-PQPEDYRPERFADESKDYDPAAYMPFGE 456 Query: 1439 GARTCLGQ 1462 G R C+ Q Sbjct: 457 GPRHCIAQ 464
>Q9VCW1:CP6D4_DROME Probable cytochrome P450 6d4 - Drosophila melanogaster (Fruit fly)| Length = 515 Score = 107 bits (266), Expect = 2e-22 Identities = 95/362 (26%), Positives = 167/362 (46%), Gaps = 37/362 (10%) Frame = +2 Query: 488 YLKATHEPLFGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARV 667 Y+ +PL I G++W R +++P F K+K M D ++ + + Sbjct: 105 YVDEERDPL-SANIFSLRGQSWRSMRHMLSPCFTSGKLKSMFSTSEDIGDKMVAHLQKEL 163 Query: 668 DKSGGTVDIKIDDDIRAYSADVISRTCFG---SSYVKGKKIFLKLRELQKAVSKPNVLAE 838 + G ++ I ++ Y+ D+I+ T FG +S+ F KL L +A ++ N Sbjct: 164 PEEGFK-EVDIKKVMQNYAIDIIASTIFGLDVNSFENPDNKFRKLVSLARANNRFNA--- 219 Query: 839 MTGLRFFPTKKNRQAW---GLHKQVHRLILEIVKESGE--------DKNLLRAILHSASS 985 M G+ F Q G V +L+IVKE+ E K+LL+ ++ ++ Sbjct: 220 MFGMMIFLVPSIAQFLFRIGFKNPVGLAMLQIVKETVEYREKHGIVRKDLLQLLIQLRNT 279 Query: 986 SKVGLGEAENFIVD-----NCKSI------------YFAGYESTAVTAAWCLMLLGLHPE 1114 K+ + ++F + + K+I Y AG E+T TAA+ + L +PE Sbjct: 280 GKIDENDEKSFSIQKTPDGHIKTISLEAITAQAFIFYIAGQETTGSTAAFTIYELAQYPE 339 Query: 1115 WQDRVRQEVLEVCGGR--PLDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKLGG 1288 R++ EV E + SL KM+ L + +QET+R YP ++R Q+ + Sbjct: 340 LLKRLQDEVDETLAKNDGKITYDSLNKMEFLDLCVQETIRKYPGLPILNRECTQDYTVPD 399 Query: 1289 VH--IPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARFSDARPQLH--SYLPFGAGARTCL 1456 + IPKG + I + +H D + + PD + ++P RFS+ + +++PFG G R C+ Sbjct: 400 TNHVIPKGTPVVISLYGIHHDAEYF-PDPETYDPERFSEESRNYNPTAFMPFGEGPRICI 458 Query: 1457 GQ 1462 Q Sbjct: 459 AQ 460
>P13527:CP6A1_MUSDO Cytochrome P450 6A1 - Musca domestica (House fly)| Length = 509 Score = 106 bits (264), Expect = 4e-22 Identities = 100/354 (28%), Positives = 166/354 (46%), Gaps = 27/354 (7%) Frame = +2 Query: 488 YLKATHEPLFGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARV 667 Y +PL G ++ GE W R ++P F K+K M + +++ Q LLE ++ Sbjct: 108 YYNEKDDPLTGH-LVMVEGEKWRSLRTKLSPTFTAGKMKYMYNTVLEVGQRLLEVMYEKL 166 Query: 668 DKSGGTVDIKIDDDIRAYSADVISRTCFG---SSYVKGKKIFLKLRELQKAVSKPNVLAE 838 + S ++ + D + ++ DVI FG +S FL + V + N L Sbjct: 167 EVSS---ELDMRDILARFNTDVIGSVAFGIECNSLRNPHDRFLAMGRKSIEVPRHNALI- 222 Query: 839 MTGLRFFPTKKNRQAWG-LHKQVHRLILEIVKESGE--DKNLLRA------IL----HSA 979 M + FP + L + VH+ + +KE+ + +KN +R +L + Sbjct: 223 MAFIDSFPELSRKLGMRVLPEDVHQFFMSSIKETVDYREKNNIRRNDFLDLVLDLKNNPE 282 Query: 980 SSSKVGLGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGG 1159 S SK+G G N + + G+E+++ T + L L + + QDR+R+EV EV Sbjct: 283 SISKLG-GLTFNELAAQVFVFFLGGFETSSSTMGFALYELAQNQQLQDRLREEVNEVFDQ 341 Query: 1160 RPLDSQSLQKMKN---LTMVIQETLRLYP--AGAFVSRMALQELKL---GGVHIPKGVNI 1315 D+ S + N L V+ ETLR YP G+ ++R L + + +PKG + Sbjct: 342 FKEDNISYDALMNIPYLDQVLNETLRKYPVGVGSALTRQTLNDYVVPHNPKYVLPKGTLV 401 Query: 1316 YIPVSTMHLDPKLWGPDAKEFNPARFSDARPQLH---SYLPFGAGARTCLGQGF 1468 +IPV +H DP+L+ P+ +EF+P RFS + +L FG G R C+G F Sbjct: 402 FIPVLGIHYDPELY-PNPEEFDPERFSPEMVKQRDSVDWLGFGDGPRNCIGMRF 454
>P13584:CP4B1_HUMAN Cytochrome P450 4B1 - Homo sapiens (Human)| Length = 511 Score = 106 bits (264), Expect = 4e-22 Identities = 89/364 (24%), Positives = 159/364 (43%), Gaps = 25/364 (6%) Frame = +2 Query: 518 GRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIK 697 GRG+L G W RK++ P F D +K V + +S + +L+ WE + + G + DI Sbjct: 123 GRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKA-REGKSFDIF 181 Query: 698 IDDDIRAYSADVISRTCFGSSYV----KGKKIFLKLRELQKAVSKPNVLAEM-TGLRFFP 862 D + + + + + FG + +L + +L + + V + ++ Sbjct: 182 CD--VGHMALNTLMKCTFGRGDTGLGHRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWL 239 Query: 863 TKKNRQAWGLHKQVHRLILEIVKE---------------SGEDKNLLRAILHSASSSKVG 997 T R+ + H ++++E + + L +L + + Sbjct: 240 TPHGRRFLRACQVAHDHTDQVIRERKAALQDEKVRKKIQNRRHLDFLDILLGARDEDDIK 299 Query: 998 LGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGRP-LDS 1174 L +A+ + + F G+++T +W L + L+PE Q R R+EV E+ G + Sbjct: 300 LSDAD--LRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQW 357 Query: 1175 QSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELK-LGGVHIPKGVNIYIPVSTMHLDPK 1351 L KM LTM I+E+ RLYP V R + + + G +P G I + + +H + Sbjct: 358 DDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMHIYALHRNSA 417 Query: 1352 LWGPDAKEFNPARFSD---ARPQLHSYLPFGAGARTCLGQGFATAEXXXXXXXXXXXFAL 1522 +W PD + F+ RFS ++ +++PF AG R C+GQ FA +E F Sbjct: 418 VW-PDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEF 476 Query: 1523 RLSP 1534 L P Sbjct: 477 SLDP 480
>Q92113:CP17A_SQUAC Cytochrome P450 17A1 - Squalus acanthias (Spiny dogfish)| Length = 509 Score = 106 bits (264), Expect = 4e-22 Identities = 117/456 (25%), Positives = 198/456 (43%), Gaps = 38/456 (8%) Frame = +2 Query: 353 YEKWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVS-LDLGKSSYLKATHEPLFGRGI 529 ++K +K +G +F+ MG + ++ +++ L + G+ S + G+ I Sbjct: 58 FQKLQKTYGNLFSLMMGPHYAVVINNHQHAKEVLLKKGKIFAGRPSMVTTDLLSRGGKDI 117 Query: 530 LKSN-GEAWAHQRKII--APEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKI 700 G AW RK++ A F D G+ ++ A ++ +E + + Sbjct: 118 AFGKYGPAWKFHRKLVLSALHLFGDGSAGIEKMICQEATSMCSTFE----RLNNAAHDMM 173 Query: 701 DDDIRAYSADVISRTCFGSSYVKGKKIFLKLRELQKA----VSKPNVLAEMTGLRFFPTK 868 D RA + +VI CF S+Y K F +R+ + V+K +++ L+FFP + Sbjct: 174 PDVTRAVT-NVICLLCFNSTYEKEDPEFQTMRKYSQGIVNTVAKDSLIDIFPWLQFFPNE 232 Query: 869 KNRQAWGLH--KQVHRLILEIVKESGEDKN--------------LLRAILHSAS--SSKV 994 LH KQ I+++ ED LL+A +++ + SS Sbjct: 233 N------LHTLKQCIATRDSILQKKFEDHKANYSSDSANDLFNILLKAKMNAENNNSSVH 286 Query: 995 GLGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGRPLDS 1174 G ++ +V I+ AG E+++ AW ++ L HPE Q ++++E+ G Sbjct: 287 EAGLTDDHMVMTVADIFGAGVETSSTAFAWMIIYLIHHPEVQKKIQEEIDSNIGFERTPK 346 Query: 1175 QSLQ-KMKNLTMVIQETLRLYPAGAF-VSRMALQELKLGGVHIPKGVNIYIPVSTMHLDP 1348 S + M L I E LR+ P + +AL + +G IPKG + I + +H D Sbjct: 347 MSDKGNMNFLNATIHEILRIQPVSPLLIPHVALADSSIGDYTIPKGTRVIINLWAIHHDE 406 Query: 1349 KLW-GPDAKEFNPARFSDARPQL-----HSYLPFGAGARTCLGQGFATAEXXXXXXXXXX 1510 K W PDA F+P RF D + SYLPFGAG R CLG+ A E Sbjct: 407 KEWKNPDA--FDPGRFLDEDGKYVCSSSESYLPFGAGTRVCLGEMLARMELFLFTSWILQ 464 Query: 1511 XFALRLSPLY---QHSPALKLIVEP-EFGVDITLTK 1606 F +++ P Y ++++P +F V + L K Sbjct: 465 RFTVQVPPGYPPPDKEGKFGIVLQPLKFKVQLKLRK 500
>Q9V4U9:C6A13_DROME Probable cytochrome P450 6a13 - Drosophila melanogaster (Fruit fly)| Length = 493 Score = 106 bits (264), Expect = 4e-22 Identities = 107/444 (24%), Positives = 203/444 (45%), Gaps = 23/444 (5%) Frame = +2 Query: 206 RQGIGGPRPSFPYGNMADXXXXXXXXXXXXXXXXXXXIVHDYRPAVLPFYEKWR--KEHG 379 R+G+ G RP + GNM+ + L Y K+R + + Sbjct: 28 RRGVAGERPVYFRGNMSGLGRDLH-----------------WTDINLRIYRKFRGVERYC 70 Query: 380 PVFTYSMGNVVFLHVSRPDVVRDINLC-VSLDLGKSSYLKATHEPLFGRGILKSNGEAWA 556 FT+ ++ + + +++RDI + S + + +PL G +L +G W Sbjct: 71 GYFTFMTKSLFIMDL---ELIRDIMIRDFSSFADRGLFHNVRDDPLTGN-LLFLDGPEWR 126 Query: 557 HQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAYSADVI 736 R+ + F K+K M MV+ + L + +V +I+ D ++ DVI Sbjct: 127 WLRQNLTQVFTSGKMKFMFPNMVEVGEKLTQACRLQVG------EIEAKDLCARFTTDVI 180 Query: 737 SRTCFGSSYVKGKKIFLKLRELQKAVSKPNVLAEMTGLRFF--PTKKNRQAWGLHK-QVH 907 FG + + R + ++V++ + + + F P + + L + +V Sbjct: 181 GSCAFGLECNSLQDPESQFRRMGRSVTQEPLHSVLVQAFMFAQPELARKLRFRLFRPEVS 240 Query: 908 RLILEIVKESGEDK--------NLLRAILHSASSSKVGLGEAENF--IVDNCKSIYFAGY 1057 L+ V+++ + + +L++ ++ G+ +A +F I + AG+ Sbjct: 241 EFFLDTVRQTLDYRRRENIHRNDLIQLLMELGEE---GVKDALSFEQIAAQALVFFLAGF 297 Query: 1058 ESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVC--GGRPLDSQSLQKMKNLTMVIQETLRL 1231 ++++ T ++CL L L+P+ Q+R+R EVL V + L S+Q+M L V+ ETLR Sbjct: 298 DTSSTTMSFCLYELALNPDVQERLRVEVLAVLKRNNQKLTYDSVQEMPYLDQVVAETLRK 357 Query: 1232 YPAGAFVSRMALQELKL--GGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARFSDAR 1405 YP + R + +E ++ + + G I IPV ++H DP+L+ PD ++F+P+RF Sbjct: 358 YPILPHLLRRSTKEYQIPNSNLILEPGSKIIIPVHSIHHDPELY-PDPEKFDPSRFEPEE 416 Query: 1406 PQLH---SYLPFGAGARTCLGQGF 1468 + +YLPFG G R C+G+ F Sbjct: 417 IKARHPFAYLPFGEGPRNCIGERF 440
>P47787:THAS_PIG Thromboxane-A synthase - Sus scrofa (Pig)| Length = 534 Score = 105 bits (263), Expect = 5e-22 Identities = 116/473 (24%), Positives = 191/473 (40%), Gaps = 61/473 (12%) Frame = +2 Query: 365 RKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRGILKSNG 544 RK++GP+ Y +G + + +S PD+++ + L + IL Sbjct: 71 RKQYGPLSGYYLGRRMIVVISDPDMIKQV-LAEKFSNFTNRMATGLESKPVADSILFLRD 129 Query: 545 EAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAYS 724 + W R ++ F K+ + L+ + LL E R +SG DI+ Y+ Sbjct: 130 KRWEEVRSVLTSAFSPKKLNKLTPLISQACDLLLAHLE-RYAESGDAFDIQ--RCYCCYT 186 Query: 725 ADVISRTCFGSS----------YVKGKKIFLKLRE----LQKAVSKPNVLAEMTGLRFFP 862 DV++ FG+ +VK + F L +S P+++ + R P Sbjct: 187 TDVVASVAFGTQVNSSEEPEHPFVKHCRRFFAFSVPRLILVLILSFPSIMVPLA--RILP 244 Query: 863 TKKNRQAWGLHKQVHRLILEIVKESGEDK---NLLRAIL---HSASSSKVGLGEAENF-- 1018 KK + G ++ R ++ + + ++ + L+ +L HSA S V ENF Sbjct: 245 NKKRDEVNGFFNKLIRNVIALRDQQAAEERRQDFLQMVLDLRHSAPSVGV-----ENFDI 299 Query: 1019 --------------------------------IVDNCKSIYFAGYESTAVTAAWCLMLLG 1102 +V AGYE T ++ LL Sbjct: 300 VRQAFSSAKGCPADPSQPHLPRPLSKPLTVDEVVGQAFLFLIAGYEIITNTLSFVTYLLA 359 Query: 1103 LHPEWQDRVRQEVLEVCGGRPLDSQ-SLQK-MKNLTMVIQETLRLYPAGAFVSRMALQEL 1276 +P+ Q+++ +EV + P SLQ+ + L MV+ ETLR+YP +R A ++ Sbjct: 360 TNPDCQEKLLREVDDFSKKHPSPEHCSLQQGLPYLDMVLSETLRMYPPAFRFTREAARDC 419 Query: 1277 KLGGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARFSDARPQLH---SYLPFGAGAR 1447 ++ G IP G + + V +H DPK W P + F+P RF+ +L +YLPFGAG R Sbjct: 420 EVLGQRIPAGTVLEVAVGALHHDPKHW-PHPETFDPERFTAEAQRLQQPFTYLPFGAGPR 478 Query: 1448 TCLGQGFATAEXXXXXXXXXXXFALRLSPLYQHSPAL--KLIVEPEFGVDITL 1600 +CLG E F P Q L K + P+ GV I + Sbjct: 479 SCLGVQLGLLEIKLTLLHILRKFRFEACPETQVPLQLESKSALSPKNGVYIRI 531
>Q9VGB5:CP135_DROME Probable cytochrome P450 313a5 - Drosophila melanogaster (Fruit fly)| Length = 487 Score = 105 bits (263), Expect = 5e-22 Identities = 104/383 (27%), Positives = 172/383 (44%), Gaps = 19/383 (4%) Frame = +2 Query: 368 KEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRGILKSNGE 547 K +G +G L P ++ DI + +SS + G G+L Sbjct: 62 KIYGKTVLTWIGLTPVLVTCEPKILEDIFTSPNCS-NRSSVVDKAISSCLGLGLLTLKNN 120 Query: 548 AWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAYSA 727 W +RK++ P F + V V ++ + A L+ VD GG DI + ++ +S Sbjct: 121 HWNERRKLLLPSFKNNAVLSFVPVLNNEANFLVTLLAEFVD--GG--DINLLPELNKWSF 176 Query: 728 DVISRTCFG------SSYVKGKKI--FLKLRELQK-AVSKPNVLAEMTGLRFFPTKKNRQ 880 + ++ G ++Y G + + L L V P + + G F K+ + Sbjct: 177 KIAAQITMGDEVRNQANYQNGNLLESYKALNNLIPIGVVMPWLRNKYLGKLFSYEKRRLE 236 Query: 881 AWGLHKQVHRLILEIV-KESGEDKNLLRAILHSASSSKVGLGEAE-NFIVDNCKSIYFAG 1054 A Q + I +I+ K+ N L + V +GE + ++ +I FA Sbjct: 237 A---ATQSNAFIKDIIDKKLSSTDNSSEPALIDRILNLVRIGELSYDDVMGEFSNIIFAA 293 Query: 1055 YESTAVTAAWCLMLLGLHPEWQDRVRQEVLEV--CGGRPLDSQS-LQKMKNLTMVIQETL 1225 ++ ++T L+L+ + P++QD V +E+ EV GG S + L+K+ L V+ ET+ Sbjct: 294 SDTLSITVNNVLILMAMFPKYQDNVFEELAEVFPSGGEFEASHADLEKLVKLDRVLHETM 353 Query: 1226 RLYPAGAFVSRMALQELKLG-GVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARF--- 1393 RL PA + R ++L G +IP+GV + I + H + +WGP A FNP F Sbjct: 354 RLIPAVPLLIRQTSHSIQLSNGFYIPEGVTLMIDIFHTHRNKDIWGPQANAFNPDNFLPE 413 Query: 1394 -SDARPQLHSYLPFGAGARTCLG 1459 ARP +SYLPF G +TCLG Sbjct: 414 NKRARPP-YSYLPFSKGKKTCLG 435
>Q43078:C97B1_PEA Cytochrome P450 97B1 - Pisum sativum (Garden pea)| Length = 552 Score = 105 bits (262), Expect = 6e-22 Identities = 111/446 (24%), Positives = 184/446 (41%), Gaps = 63/446 (14%) Frame = +2 Query: 332 RPAVLPFYEKWRKEHGPVFTYSMGNVVFLHVSRPDVVRDI--NLCVSLDLGKSSYLKATH 505 RP Y+ W EHG V+ + G F+ VS P V R I S D G L Sbjct: 101 RPLFFSLYD-WFLEHGSVYKLAFGPKAFVVVSDPIVARHILRENAFSYDKG---VLADIL 156 Query: 506 EPLFGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVD-SAQTLL---EPWEARVDK 673 EP+ G+G++ ++ E W +R++IAP F ++ MV L S +T+L E E Sbjct: 157 EPIMGKGLIPADLETWKQRRRVIAPGFHTSYLEAMVQLFTSCSERTVLKVNELLEGEGRD 216 Query: 674 SGGTVDIKIDDDIRAYSADVISRTCFGSSYVKGKKIFLKLRELQKAVSKPNVLAEMTGLR 853 +V++ ++ + + ++I F + + KAV AE Sbjct: 217 GQKSVELDLEAEFSNLALEIIGLGVFNYDFGS----VTNESPVIKAVYGTLFEAEHRSTF 272 Query: 854 FFPTKKNRQA-WGLHKQ---------VHRLILEIVKESGEDK--------------NLLR 961 + P K A W + +Q ++ + +++ + E + NL Sbjct: 273 YIPYWKFPLARWIVPRQRKFQDDLKVINTCLDGLIRNAKESRQETDVEKLQQRDYSNLKD 332 Query: 962 AILHSASSSKVGLGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEV 1141 A L G+ + + D+ ++ AG+E+TA W + LL +P+ + + EV Sbjct: 333 ASLLRFLVDMRGVDVDDRQLRDDLMTMLIAGHETTAAVLTWAVFLLAQNPDKMKKAQAEV 392 Query: 1142 LEVCGGRPLDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKLGGVH--------I 1297 V G + L+K++ + +++ ETLRLYP + R +L+ L G H I Sbjct: 393 DLVLGMGKPTFELLKKLEYIRLIVVETLRLYPQPPLLIRRSLKPDVLPGGHKGDKDGYTI 452 Query: 1298 PKGVNIYIPVSTMHLDPKLWGPDAKEFNPARF-----------------SDARPQLH--- 1417 P G +++I V +H P W +F P RF S + L+ Sbjct: 453 PAGTDVFISVYNLHRSPYFW-DRPNDFEPERFLVQNNNEEVEGWAGFDPSRSPGALYPNE 511 Query: 1418 -----SYLPFGAGARTCLGQGFATAE 1480 ++LPFG G R C+G FA E Sbjct: 512 IISDFAFLPFGGGPRKCVGDQFALME 537
>Q9VVN6:CP312_DROME Probable cytochrome P450 312a1 - Drosophila melanogaster (Fruit fly)| Length = 510 Score = 105 bits (261), Expect = 8e-22 Identities = 101/392 (25%), Positives = 178/392 (45%), Gaps = 34/392 (8%) Frame = +2 Query: 398 MGNVVFLHVSRPDVVRDIN-LCVSLDLGKSSYLKATHEPLFGRGILKSNGEAWAHQRKII 574 MG ++L P +DI LC + L + + E G+ S E W+H+RKI+ Sbjct: 78 MGTKLYLVDCNP---KDIQALCSAQQLLQKTNDYRVFENWLCEGLFTSGFEKWSHRRKIV 134 Query: 575 APEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAYSADVISRTCFG 754 P F +K V + ++ LL A+ +SG +D I ++ D I T G Sbjct: 135 MPAFNYTMIKQFVAVFEKQSRILLTN-VAKFAESGDQIDFL--QLISCFTLDTICETALG 191 Query: 755 ----------SSYVKGKKIFLKL--RELQKAVSKPNVLAEMTGLRFFPTKKNRQAWGLHK 898 S Y+ K L + + L+ + + + + T + + G + Sbjct: 192 VSVGSQSSAKSEYLDAVKSILVIIDKRLKNIFYRNSFIFKRTSHYKREQELIKTLHGFTE 251 Query: 899 QVHRLILEIVKESGEDKNLLRA------------ILHSASSSKVGLGEAENF--IVDNCK 1036 + + ++ + + E++N + L + SK G+ I + Sbjct: 252 GIIQKRIDEINQDAENRNYQSSDAELDGVKRTLCFLDTLLLSKGPDGKPLTVKDIREEVD 311 Query: 1037 SIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCG---GRPLDSQSLQKMKNLTM 1207 +I F G++ TA T + + + LHPE Q R R+EV VCG P+ + +++++ L Sbjct: 312 TIIFGGFDLTATTLNFFMYNMTLHPEHQQRCREEVWSVCGKDKSEPISIEQVRQLEFLEA 371 Query: 1208 VIQETLRLYPAGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDP-KLWGPDAKEFNP 1384 I+ETLR+YP+G +R A + IPKG ++ I S +++ K + PD F P Sbjct: 372 CIKETLRMYPSGPLTARKATANCTINDFFIPKGSDVII--SPIYMGRCKDFFPDPMVFKP 429 Query: 1385 ARFS-DARPQLH--SYLPFGAGARTCLGQGFA 1471 R++ A P++ +++PF AGAR+C+GQ +A Sbjct: 430 DRWAIGAEPKIEATTFIPFMAGARSCMGQRYA 461
>Q9LTM1:C71BM_ARATH Cytochrome P450 71B22 - Arabidopsis thaliana (Mouse-ear cress)| Length = 500 Score = 105 bits (261), Expect = 8e-22 Identities = 101/402 (25%), Positives = 176/402 (43%), Gaps = 33/402 (8%) Frame = +2 Query: 353 YEKWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRGI- 529 + K + +GPV G V + VS + ++ + DL + K T LF Sbjct: 52 FHKLSQNYGPVMFLHFGVVPVVVVSTREAAEEV--LKTHDLETCTRPKLTATKLFSYNYK 109 Query: 530 ---LKSNGEAWAHQRKIIAPEFFLDK-VKGMVDLMVDSAQTLLEPWEARVDKSGGT---V 688 G+ W RK+ E F K +K + + ++ L+ ++ KS T V Sbjct: 110 DIGFAQYGDDWREMRKLAMLELFSSKKLKAFRYIREEESEVLVN----KLSKSAETRTMV 165 Query: 689 DIKIDDDIRAYSADVISRTCFGSSYVKGKKIFLKLRELQKAVSKPNVLAEMTGLRFFPTK 868 D++ + +Y+A ++ R FG ++ + + + E S+ N L FFP Sbjct: 166 DLR--KALFSYTASIVCRLAFGQNFHECDFVDMDKVEDLVLESETN-LGSFAFTDFFPAG 222 Query: 869 KN---RQAWGLHKQVHRLILEIVK-------------ESGEDKNLLRAILHSASS-SKVG 997 + G H ++H+ + +S + +++ +L + SKVG Sbjct: 223 LGWVIDRISGQHSELHKAFARLSNFFQHVIDDHLKPGQSQDHSDIIGVMLDMINKESKVG 282 Query: 998 LGEAE-NFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGG--RPL 1168 + + + ++ AG + A+T W + L HP +++QE+ E+ G + Sbjct: 283 SFQVTYDHLKGVMSDVFLAGVNAGAITMIWAMTELARHPRVMKKLQQEIREILGDNKEKI 342 Query: 1169 DSQSLQKMKNLTMVIQETLRLY-PAGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLD 1345 Q L+K+ L +VI+ET RL+ PA + R + +LK+ G +IPK I I ++ D Sbjct: 343 TEQDLEKVHYLKLVIEETFRLHPPAPLLLPRETMSDLKIQGYNIPKNTMIEINTYSIGRD 402 Query: 1346 PKLWGPDAKEFNPARFSDA----RPQLHSYLPFGAGARTCLG 1459 P W + +FNP RF D+ + Q + LPFGAG R C G Sbjct: 403 PNCW-ENPNDFNPERFIDSPVEYKGQHYELLPFGAGRRICPG 443
>Q9VL92:CP4E3_DROME Cytochrome P450 4e3 - Drosophila melanogaster (Fruit fly)| Length = 526 Score = 104 bits (260), Expect = 1e-21 Identities = 95/405 (23%), Positives = 172/405 (42%), Gaps = 28/405 (6%) Frame = +2 Query: 350 FYEKWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRGI 529 F++ W F + +G + ++ P + I L + KS+ H P G G+ Sbjct: 59 FFDWWYDYGKDNFLFWIGYSSHIVMTNPKQLEYILNSQQL-IQKSTIYDLLH-PWLGHGL 116 Query: 530 LKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDD 709 L S G W RK+I P F + ++ ++M +++ + + S G I + Sbjct: 117 LTSFGSKWHKHRKMITPSFHFNILQDFHEVMNENSAKFMTQLKKA---SAGDTIIDFQEH 173 Query: 710 IRAYSADVISRTCFGSSYVKGKKIFLKLRELQKAVSKPNVLAEMTGLRFFPTKKNRQAWG 889 + DVI T G ++ R+ + ++ + F P K++ + + Sbjct: 174 ANYLTLDVICDTAMGVPINA-----MEQRDSSIVQAFRDMCYNINMRAFHPFKRSNRVFS 228 Query: 890 LH----------KQVHRLILEIVKE-----------SGEDKNLLR---AILHSASSSKV- 994 L K + +I+++ D +L R A L + SS + Sbjct: 229 LTPEFSAYQKTLKTLQDFTYDIIEKRVYALQNGGSKEDHDPSLPRKKMAFLDTLLSSTID 288 Query: 995 GLGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCG---GRP 1165 G I + + F G+++T ++ + LL HP+ Q ++ +E EV G R Sbjct: 289 GRPLTRQEIYEEVSTFMFEGHDTTTSGVSFSVYLLSRHPDVQRKLYREQCEVMGHDMNRS 348 Query: 1166 LDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLD 1345 + Q + KMK L + I+E R+YP+ F+ R ++ + G +PKG + + + + + Sbjct: 349 VSFQEIAKMKYLDLFIKEAQRVYPSVPFIGRYCDKDYDINGSIVPKGTTLNLALILLGYN 408 Query: 1346 PKLWGPDAKEFNPARFSDARPQLHSYLPFGAGARTCLGQGFATAE 1480 +++ D F P RF + +P YLPF AG R C+GQ FA E Sbjct: 409 DRIF-KDPHHFRPERFEEEKPAPFEYLPFSAGPRNCIGQKFALLE 452
>P15129:CP4B1_RAT Cytochrome P450 4B1 - Rattus norvegicus (Rat)| Length = 511 Score = 104 bits (260), Expect = 1e-21 Identities = 95/393 (24%), Positives = 166/393 (42%), Gaps = 25/393 (6%) Frame = +2 Query: 518 GRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIK 697 G+G+L +G W RK++ P F D +K V + +S + +L+ WE + ++ Sbjct: 123 GKGLLVLDGPKWFQHRKLLTPGFHYDVLKPYVAIFAESTRMMLDKWEKKASENKS---FD 179 Query: 698 IDDDIRAYSADVISRTCFGSSYV----KGKKIFLKLRELQKAVSKP-NVLAEMTGLRFFP 862 I D+ + D + + FG + +L + +L + + + ++ Sbjct: 180 IFCDVGHMALDTLMKCTFGKGDSGLGHRDNSYYLAVSDLTLLMQQRIDSFQYHNDFIYWL 239 Query: 863 TKKNRQAWGLHKQVHRLILEIVKE-------SGEDKNL--------LRAILHSASSSKVG 997 T R+ K H E++++ E K + L +L S + Sbjct: 240 TPHGRRFLRACKIAHDHTDEVIRQRKAALQDEKERKKIQQRRHLDFLDILLGVRDESGIK 299 Query: 998 LGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGRP-LDS 1174 L +AE + + F G+++T +W L + L+PE Q R+EV + G + Sbjct: 300 LSDAE--LRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQQLCREEVRGILGDQDSFQW 357 Query: 1175 QSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELK-LGGVHIPKGVNIYIPVSTMHLDPK 1351 L KM LTM ++E RLYP V R + + + G +P G I + + +H + Sbjct: 358 DDLAKMTYLTMCMKECFRLYPPVPQVYRQLNKPVTFVDGRSLPAGSLISLHIYALHRNST 417 Query: 1352 LWGPDAKEFNPARFSD---ARPQLHSYLPFGAGARTCLGQGFATAEXXXXXXXXXXXFAL 1522 +W PD + F+P RFS A +++PF AG R C+GQ FA E F Sbjct: 418 VW-PDPEVFDPLRFSPENAAGRHPFAFMPFSAGPRNCIGQQFAMNEMKVVTALCLLRFEF 476 Query: 1523 RLSPLYQHSPALKLIVEPEFGVDITLTKVQTAS 1621 L P +LI+ + G+ + L + + S Sbjct: 477 SLDPSKMPIKVPQLILRSKNGIHLYLKPLASRS 509
>Q9V771:C6A23_DROME Probable cytochrome P450 6a23 - Drosophila melanogaster (Fruit fly)| Length = 502 Score = 104 bits (260), Expect = 1e-21 Identities = 113/448 (25%), Positives = 191/448 (42%), Gaps = 25/448 (5%) Frame = +2 Query: 200 FRRQGIGGPRPSFPYGNMADXXXXXXXXXXXXXXXXXXXIVHDYRPAVLPFYEKWRKEHG 379 ++R+GI P YGNM D Y+ +V PF G Sbjct: 26 WQRRGIPHDVPHPIYGNMKDWPKKRHIAMIFRDYYTK------YKRSVYPFA-------G 72 Query: 380 PVFTYSMGNVVF-LHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRGILKSNGEAWA 556 F ++ V+ L + + +++D N + + + +PL + G+ W Sbjct: 73 FYFFFTRSAVITDLELVKRVLIKDFNHFEN----RGIFYNEIDDPLSAT-LFSIEGQKWR 127 Query: 557 HQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAYSADVI 736 H R + P F K+K M ++V + + + + A+ G V ++I D + Y+ADVI Sbjct: 128 HLRHKLTPTFTSGKMKNMFPIIVKVGEEMEKIFSAKTTTGEGQV-LEIVDLVARYTADVI 186 Query: 737 SRTCFG---SSYVKGKKIFLKLRELQKAVSKPNVLAEMTGLRF-FPTKKNRQAWGLHKQ- 901 FG +S F+ + + +A+ + + L F FP R L+ Q Sbjct: 187 GNCAFGLNCNSLQNPNAEFVTIGK--RAIIERRYGGLLDFLIFGFPKLSRRLRLKLNVQD 244 Query: 902 VHRLILEIVKESGEDKNLLRAILHSASSSKVGLGEAE-----------NFIVDNCKSIYF 1048 V IV+ + + + H S + + E E N I+ + Sbjct: 245 VEDFYTSIVRNTIDYRLRTNEKRHDFMDSLIEMYEKEQAGNTEDGLSFNEILAQAFIFFV 304 Query: 1049 AGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCG--GRPLDSQSLQKMKNLTMVIQET 1222 AG+E+++ T + L L L + QD++R E+ V + +++MK L V+ ET Sbjct: 305 AGFETSSTTMGFALYELALDQDIQDQLRAEINNVLSKHNNEFTYEGIKEMKYLEQVVMET 364 Query: 1223 LRLYPAGAFVSRMALQELKLGG--VHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARFS 1396 LR YP A ++RM + I KG + IP +H DP+++ P+ ++F P RF+ Sbjct: 365 LRKYPVLAHLTRMTQTDFSPEDPKYFIAKGTTVVIPALGIHYDPEIY-PEPEKFKPERFT 423 Query: 1397 D----ARPQLHSYLPFGAGARTCLGQGF 1468 D ARP ++LPFG G R C+G F Sbjct: 424 DEAIAARPSC-TWLPFGEGPRNCIGLRF 450
>Q9V674:CP6G1_DROME Cytochrome P450 6g1 - Drosophila melanogaster (Fruit fly)| Length = 524 Score = 104 bits (259), Expect = 1e-21 Identities = 100/382 (26%), Positives = 171/382 (44%), Gaps = 41/382 (10%) Frame = +2 Query: 437 VVRDINLCVSL---DLGK--SSYLKATH--EPLFGRGILKSNGEAWAHQRKIIAPEFFLD 595 ++RDI L S+ D + + Y + +PL + W R + P F Sbjct: 85 IIRDIELIKSILIKDFNRFHNRYARCDPHGDPLGYNNLFFVRDAHWKGIRTKLTPVFTSG 144 Query: 596 KVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAYSADVISRTCFGSSYVK-- 769 KVK M LM + + L + R +K+ G+ +I + +S D I+ FG Sbjct: 145 KVKQMYTLMQEIGKDLELALQRRGEKNSGSFITEIKEICAQFSTDSIATIAFGIRANSLE 204 Query: 770 ---------GKKIFL----KLRELQKAVSKPNVLAEMTGLRFFPTKKNRQAWGLHKQVHR 910 G+K+F + ++ A P +++ M ++FF + + Sbjct: 205 NPNAEFRNYGRKMFTFTVARAKDFFVAFFLPKLVSLMR-IQFFTADFSH----FMRSTIG 259 Query: 911 LILEIVKESGEDKNLLRAILHS------ASSSKVGLGEAENFIVDNCKSIYFAGYESTAV 1072 ++E + SG +N L +L S A SK + ++F+V + AG+E+++ Sbjct: 260 HVMEERERSGLLRNDLIDVLVSLRKEAAAEPSKPHYAKNQDFLVAQAGVFFTAGFETSSS 319 Query: 1073 TAAWCLMLLGLHPEWQDRVRQEVLE--VCGGRPLDSQSLQKMKNLTMVIQETLRLYPAGA 1246 T ++ L + HPE Q R+R E+ E V GG L + +Q ++ L MV+ E LR+YP Sbjct: 320 TMSFALYEMAKHPEMQKRLRDEINEALVEGGGSLSYEKIQSLEYLAMVVDEVLRMYPVLP 379 Query: 1247 FVSR-----MALQELKLGGVH---IPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARFSDA 1402 F+ R +L L + + G ++IP+ +H DPK W + +F+P RFS A Sbjct: 380 FLDREYESVEGQPDLSLKPFYDYTLENGTPVFIPIYALHHDPKYW-TNPSQFDPERFSPA 438 Query: 1403 RPQ---LHSYLPFGAGARTCLG 1459 + +Y PFG+G C+G Sbjct: 439 NRKNIVAMAYQPFGSGPHNCIG 460
>Q27664:CP6B2_HELAM Cytochrome P450 6B2 - Helicoverpa armigera (Cotton bollworm)| (Heliothis armigera) Length = 504 Score = 104 bits (259), Expect = 1e-21 Identities = 121/474 (25%), Positives = 201/474 (42%), Gaps = 32/474 (6%) Frame = +2 Query: 143 LALYLYYTVWVVPQRLLAGFRRQGIGGPRPSFPYGNMADXXXXXXXXXXXXXXXXXXXIV 322 + LY Y+T R ++++ + GP P +GN+ D +V Sbjct: 15 VTLYFYFT------RTFNYWKKRNVRGPEPVVFFGNLKDSALRKKNMG----------VV 58 Query: 323 HDYRPAVLPFYEKWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKAT 502 + + P E + Y M + L V +V++ I + ++ L+ + Sbjct: 59 MEELYNMFP-------EEKVIGIYRMTSPCLL-VRDLEVIKHI-MIKDFEVFSDRGLEFS 109 Query: 503 HEPLFGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGG 682 E L G+ + ++G+ W R P F K+K M LM + A ++ +K Sbjct: 110 KEGL-GQNLFHADGDTWRTLRNRFTPIFTSGKLKNMFYLMNEGADNFIDHVSKECEKHQ- 167 Query: 683 TVDIKIDDDIRAYSADVISRTCFGSSYVKGKKIFLKLRELQKAVSKPNVLAEMT------ 844 + +I ++ Y+ IS FG SY L + K +S+P+ E+ Sbjct: 168 --EFEIHTLLQTYTMSTISSCAFGVSYDTISDKLDTLAIVDKIISEPSYAIELDMMYPGL 225 Query: 845 ----GLRFFPTKKNRQAWGLHKQVHRLILEIV-----KESGEDKNLLRAILH-----SAS 982 L FP+ +HK L+ IV K SG + + + IL + Sbjct: 226 LPKLNLSIFPSV-------VHKFFKNLVNTIVTQRNGKPSGRN-DFMDLILELRQMGEIT 277 Query: 983 SSKVG-----LGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLE 1147 S+K G L E+ + Y AGYE++A T A+ L L+P+ Q+++ E+ E Sbjct: 278 SNKYGNNMSTLEITESVMCAQAFVFYIAGYETSATTMAYLTYQLALNPDIQNKLIAEIDE 337 Query: 1148 V--CGGRPLDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKLGG--VHIPKGVNI 1315 G + +++ MK L V ETLR+Y + R A+++ KL G V I K + Sbjct: 338 AIKANGGKVTYDTVKDMKYLNKVFDETLRMYSIVEPLQRKAIRDYKLPGTDVVIEKDTVV 397 Query: 1316 YIPVSTMHLDPKLWGPDAKEFNPAR-FSDARPQLH--SYLPFGAGARTCLGQGF 1468 I +H DPK + + K+FNP R F++ + H +YLPFG G R C+G F Sbjct: 398 LISPRGIHYDPKYY-DNPKQFNPERFFAEEVGKRHPCAYLPFGLGQRNCIGMRF 450
>Q9VGB4:CP132_DROME Probable cytochrome P450 313a2 - Drosophila melanogaster (Fruit fly)| Length = 493 Score = 103 bits (258), Expect = 2e-21 Identities = 94/391 (24%), Positives = 177/391 (45%), Gaps = 28/391 (7%) Frame = +2 Query: 371 EHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRGILKSNGEA 550 +HG + +G + P + + L + +SS G G+L G Sbjct: 64 KHGSTYMAWIGTTPIVITRDPKIAEKV-LTSPFCINRSSQTTNALALSMGYGLLTLQGSK 122 Query: 551 WAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAYSAD 730 W +RK + P F + + + L+ +++ V + G D+ D+ +S Sbjct: 123 WMARRKHMNPAFKHSVLLSFLPIFNAETDLLVSVFDSFVGQ--GEKDVL--SDLIRWSFA 178 Query: 731 VISRTCFGSSYVKGKKI-----------FLKLRELQKAVS--KPNVLAEMTGLRFFPTKK 871 + ++T G+ K L+L + V + +++++ GL + + Sbjct: 179 IATQTTLGTDVTKDDNFENDAILKTYQSMLRLTIINIFVPFVQNKIVSKLFGLEWL---R 235 Query: 872 NRQAWGLHKQVHRLILEIVKESGED--KNLLRAILHSA----SSSKVGLGEAENFIVDNC 1033 R A ++K ++ ++ + + + E+ ++ L+ ++H A + ++ L E + C Sbjct: 236 RRDASAINKMINNILDKKLNSNPENYCESELKTVIHRAIELFRNDEMSLME----LGAEC 291 Query: 1034 KSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLE---VCGGRPLDSQSLQKMKNLT 1204 S+ A +E++A T + L+LL + PE Q+ V E+ E + G + LQ++ L Sbjct: 292 SSMVLAAFETSAHTVYYALVLLAMFPEHQEMVFNEIKEHFPLAKGIEVTHTDLQQLVYLD 351 Query: 1205 MVIQETLRLYPAGAFVSRMALQELKLG-GVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFN 1381 V+ ETLRL P+ F SR L++L+L GV IPKG+ I I + + WG +A +FN Sbjct: 352 RVLNETLRLMPSVPFSSRETLEDLRLSNGVVIPKGMTISIDIFNTQRNTDYWGSEAAQFN 411 Query: 1382 PARF-----SDARPQLHSYLPFGAGARTCLG 1459 P F D P ++++PF G R C+G Sbjct: 412 PENFLPEKIHDRHP--YAFIPFSKGKRNCIG 440
>P49430:THAS_RAT Thromboxane-A synthase - Rattus norvegicus (Rat)| Length = 533 Score = 103 bits (257), Expect = 2e-21 Identities = 112/421 (26%), Positives = 189/421 (44%), Gaps = 56/421 (13%) Frame = +2 Query: 365 RKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEP-LFGRGILKSN 541 R+ +GP+ Y +G +++ +S PD+++++ V S+ + + EP L +L Sbjct: 71 RERYGPLCGYYLGRRMYIVISDPDMIKEV--LVENFSNFSNRMASGLEPKLIADSVLMLR 128 Query: 542 GEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAY 721 W R + F +K+ M L+ + + LL + SG DI+ R Y Sbjct: 129 DRRWEEVRGALMSAFSPEKLNEMTPLISQACELLLSHLKHSA-ASGDAFDIQ-----RCY 182 Query: 722 ---SADVISRTCFG---SSYVKGKKIFLKLRELQKAVSKPNVLAEMTG---------LRF 856 + +V++ FG +S + F++ + A S P L + R Sbjct: 183 CCFTTNVVASVAFGIEVNSQDAPEDPFVQHCQRVFAFSTPRPLLALILSFPSIMVPLARI 242 Query: 857 FPTKKNRQAWGLHKQVHRLILEIV-KESGEDK--NLLRAILHSASS-SKVGLGEAENFIV 1024 P K + G + R ++ + K++ E++ + L+ +L + S S VG+ EA + + Sbjct: 243 LPNKNRDELNGFFNTLIRNVIALRDKQTAEERRGDFLQMVLDAQRSMSSVGV-EAFDMVT 301 Query: 1025 DNCKS-------------------------------IYFAGYESTAVTAAWCLMLLGLHP 1111 + S AG+E T T ++ LL HP Sbjct: 302 EALSSAECMGDPPQRCHPTSTAKPLTVDEIAGQAFLFLIAGHEITTNTLSFITYLLATHP 361 Query: 1112 EWQDRVRQEVLEVCGGRPLDSQ-SLQK-MKNLTMVIQETLRLYPAGAFVSRMALQELKLG 1285 E Q+R+ +EV P +LQ+ + L MV+ ETLR+YP +R A Q+ ++ Sbjct: 362 ECQERLLKEVDLFMEKHPAPEYCNLQEGLPYLDMVVAETLRMYPPAFRFTREAAQDCEVL 421 Query: 1286 GVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARF-SDARPQL--HSYLPFGAGARTCL 1456 G HIP G + I V +H DP+ W P+ + F+P RF ++AR Q +YLPFGAG R+CL Sbjct: 422 GQHIPAGSVLEIAVGALHHDPEHW-PNPETFDPERFTAEARLQQKPFTYLPFGAGPRSCL 480 Query: 1457 G 1459 G Sbjct: 481 G 481
>P24557:THAS_HUMAN Thromboxane-A synthase - Homo sapiens (Human)| Length = 533 Score = 103 bits (256), Expect = 3e-21 Identities = 106/419 (25%), Positives = 185/419 (44%), Gaps = 54/419 (12%) Frame = +2 Query: 365 RKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRGILKSNG 544 RK +GP+ Y +G +F+ +S PD+++ + L + + +L Sbjct: 71 RKLYGPLCGYYLGRRMFIVISEPDMIKQV-LVENFSNFTNRMASGLEFKSVADSVLFLRD 129 Query: 545 EAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAYS 724 + W R + F +K+ MV L+ + LL + R +SG DI+ Y+ Sbjct: 130 KRWEEVRGALMSAFSPEKLNEMVPLISQACDLLLAHLK-RYAESGDAFDIQ--RCYCNYT 186 Query: 725 ADVISRTCFGSS----------YVKGKKIFLKL----RELQKAVSKPNVLAEMTGLRFFP 862 DV++ FG+ +VK K F + L +S P+++ + R P Sbjct: 187 TDVVASVPFGTPVDSWQAPEDPFVKHCKRFFEFCIPRPILVLLLSFPSIMVPLA--RILP 244 Query: 863 TKKNRQAWGLHKQVHRLILEIVKESGED---KNLLRAILHSA-SSSKVGLGE----AENF 1018 K + G ++ R ++ + + + ++ L+ +L + S+S +G+ + + F Sbjct: 245 NKNRDELNGFFNKLIRNVIALRDQQAAEERRRDFLQMVLDARHSASPMGVQDFDIVRDVF 304 Query: 1019 IVDNCKS--------------------------IYFAGYESTAVTAAWCLMLLGLHPEWQ 1120 CK AGYE T ++ LL +P+ Q Sbjct: 305 SSTGCKPNPSRQHQPSPMARPLTVDEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQ 364 Query: 1121 DRVRQEVLEVCGGRPLDSQ--SLQK-MKNLTMVIQETLRLYPAGAFVSRMALQELKLGGV 1291 +++ +EV +V + + + SL++ + L MVI ETLR+YP +R A Q+ ++ G Sbjct: 365 EKLLREV-DVFKEKHMAPEFCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQ 423 Query: 1292 HIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARFSDARPQLH---SYLPFGAGARTCLG 1459 IP G + + V +H DP+ W P + FNP RF+ Q H +YLPFGAG R+CLG Sbjct: 424 RIPAGAVLEMAVGALHHDPEHW-PSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLG 481
>Q59990:CP120_SYNY3 Putative cytochrome P450 120 - Synechocystis sp. (strain PCC 6803)| Length = 444 Score = 103 bits (256), Expect = 3e-21 Identities = 106/424 (25%), Positives = 184/424 (43%), Gaps = 15/424 (3%) Frame = +2 Query: 350 FYEKWRKEHGPVFTYSM--GNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGR 523 F +K +++ GP+F + NV+F+ + + + ++++ +T L Sbjct: 35 FGKKRQQQFGPIFKTRLFGKNVIFISGA---LANRFLFTKEQETFQATWPLSTRILLGPN 91 Query: 524 GILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKID 703 + GE +RKI+ F + + M Q LE W G ++ Sbjct: 92 ALATQMGEIHRSRRKILYQAFLPRTLDSYLPKMDGIVQGYLEQW-------GKANEVIWY 144 Query: 704 DDIRAYSADVISRTCFGSSYVKGKKIFLKLRELQKAVSKPNVLAEMTGLRFFPTKKNRQA 883 +R + DV + G + ++F P + GL P Sbjct: 145 PQLRRMTFDVAATLFMGEKVSQNPQLF------------PWFETYIQGLFSLPIPLPNTL 192 Query: 884 WGLHKQVHRLIL----EIVK----ESGEDKNLLRAILHSASSSKVGLGEAENFIVDNCKS 1039 +G ++ L+L +I+K + +++ L +L + + L E + D Sbjct: 193 FGKSQRARALLLAELEKIIKARQQQPPSEEDALGILLAARDDNNQPLSLPE--LKDQILL 250 Query: 1040 IYFAGYES-TAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGRPLDSQSLQKMKNLTMVIQ 1216 + FAG+E+ T+ +++CL LLG H + ++RVRQE ++ + L +++L+KM L V+Q Sbjct: 251 LLFAGHETLTSALSSFCL-LLGQHSDIRERVRQEQNKLQLSQELTAETLKKMPYLDQVLQ 309 Query: 1217 ETLRLYPAGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARFS 1396 E LRL P R +Q+ + G H PKG + +S H DP L+ PD ++F+P RF+ Sbjct: 310 EVLRLIPPVGGGFRELIQDCQFQGFHFPKGWLVSYQISQTHADPDLY-PDPEKFDPERFT 368 Query: 1397 DARPQLH----SYLPFGAGARTCLGQGFATAEXXXXXXXXXXXFALRLSPLYQHSPALKL 1564 H +++PFG G R CLG+ FA E F L P L+L Sbjct: 369 PDGSATHNPPFAHVPFGGGLRECLGKEFARLEMKLFATRLIQQFDWTLLP----GQNLEL 424 Query: 1565 IVEP 1576 +V P Sbjct: 425 VVTP 428
>P14779:CPXB_BACME Bifunctional P-450:NADPH-P450 reductase - Bacillus megaterium| Length = 1049 Score = 102 bits (255), Expect = 4e-21 Identities = 98/384 (25%), Positives = 171/384 (44%), Gaps = 14/384 (3%) Frame = +2 Query: 371 EHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRGILKS--NG 544 E G +F + V ++S ++++ D S LK + G G+ S + Sbjct: 36 ELGEIFKFEAPGRVTRYLSSQRLIKEACDESRFDKNLSQALKFVRD-FAGDGLFTSWTHE 94 Query: 545 EAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAYS 724 + W I+ P F +KG +MVD A L++ WE + I++ +D+ + Sbjct: 95 KNWKKAHNILLPSFSQQAMKGYHAMMVDIAVQLVQKWE----RLNADEHIEVPEDMTRLT 150 Query: 725 ADVISRTCFG---SSYVKGKK---IFLKLRELQKAVSKPNVLAEMTGLRFFPTKKNRQAW 886 D I F +S+ + + I +R L +A++K L + RQ Sbjct: 151 LDTIGLCGFNYRFNSFYRDQPHPFITSMVRALDEAMNK---LQRANPDDPAYDENKRQFQ 207 Query: 887 GLHKQVHRLILEIV---KESGEDKNLLRAILHSASSSKVGLGEAENFIVDNCKSIYFAGY 1057 K ++ L+ +I+ K SGE + L + + + G + I + AG+ Sbjct: 208 EDIKVMNDLVDKIIADRKASGEQSDDLLTHMLNGKDPETGEPLDDENIRYQIITFLIAGH 267 Query: 1058 ESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGRPLDSQSLQKMKNLTMVIQETLRLYP 1237 E+T+ ++ L L +P + +E V + ++++K + MV+ E LRL+P Sbjct: 268 ETTSGLLSFALYFLVKNPHVLQKAAEEAARVLVDPVPSYKQVKQLKYVGMVLNEALRLWP 327 Query: 1238 AGAFVSRMALQELKLGGVH-IPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARFSD--ARP 1408 S A ++ LGG + + KG + + + +H D +WG D +EF P RF + A P Sbjct: 328 TAPAFSLYAKEDTVLGGEYPLEKGDELMVLIPQLHRDKTIWGDDVEEFRPERFENPSAIP 387 Query: 1409 QLHSYLPFGAGARTCLGQGFATAE 1480 Q H++ PFG G R C+GQ FA E Sbjct: 388 Q-HAFKPFGNGQRACIGQQFALHE 410
>Q9GQM9:CP6L1_BLAGE Cytochrome P450 6l1 - Blattella germanica (German cockroach)| Length = 503 Score = 102 bits (255), Expect = 4e-21 Identities = 58/158 (36%), Positives = 94/158 (59%), Gaps = 7/158 (4%) Frame = +2 Query: 1007 AENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEV--CGGRPLDSQS 1180 +E+ ++ + AG+E+T+ A+ + L LHPE QDR+R E+ EV C G + + Sbjct: 284 SEHEVLGQAMLFFAAGFETTSSAMAFAMYELALHPEIQDRLRTEIQEVTACHGGQVTYEG 343 Query: 1181 LQKMKNLTMVIQETLRLYPAGAFVSRMALQELKLGG--VHIPKGVNIYIPVSTMHLDPKL 1354 ++KM L MV+ E LR YP +F+ R+ L + + G V I KG I++ + +H D + Sbjct: 344 VKKMSYLDMVVSEVLRKYPPMSFIDRVCLHDYHIPGTDVVIEKGTPIFVSLLGLHRD-SI 402 Query: 1355 WGPDAKEFNPARFS-DARPQLH--SYLPFGAGARTCLG 1459 + PD ++FNP RF+ + + +H SY+PFG G R C+G Sbjct: 403 FYPDPEDFNPERFNKEKKSGVHPFSYIPFGDGPRNCIG 440
>O49858:C82A3_SOYBN Cytochrome P450 82A3 - Glycine max (Soybean)| Length = 527 Score = 102 bits (255), Expect = 4e-21 Identities = 99/398 (24%), Positives = 176/398 (44%), Gaps = 35/398 (8%) Frame = +2 Query: 371 EHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRGI--LKSNG 544 ++GP+FT +G L +S ++ +++ L + L A + + L G Sbjct: 70 KYGPLFTIKLGMKPALVLSNWEMSKELFTTNDLAVSSRPKLVAVEVMSYNQAFVGLAPYG 129 Query: 545 EAWAHQRKIIAPEFFLDK-VKGMVDLMVDSAQT----LLEPWE-ARVDKSGGT-VDIKID 703 W RKI+ EF ++ ++ + V +T L + W ++S T VDIK Sbjct: 130 PYWRELRKIVTFEFLSNRRIEQRNHIRVSEVRTSIKELFDIWSNGNKNESRYTLVDIKQW 189 Query: 704 DDIRAYSADV---ISRTCFGSSYVKGK----KIFLKLRELQKAVSKPNVLAEMTGLRFFP 862 ++ V + + FG +V+GK + +RE + V + LR+ Sbjct: 190 LAYLTFNMVVRMVVGKRYFGVMHVEGKDKAQRFMKNIREFMNLMGTFTVADGVPCLRWLD 249 Query: 863 TKKNRQAWGLH-KQVHRLILEIVKESGE----------DKNLLRAILHSASSSKVGLGEA 1009 + +A + K+V +L+ E ++E + D++ + ++ + + +++G +A Sbjct: 250 LGGHEKAMKANAKEVDKLLSEWLEEHRQKKLLGENVESDRDFMDVMISALNGAQIGAFDA 309 Query: 1010 ENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEV-LEVCGGRPLDSQSLQ 1186 + + G +STAVT W L LL +P + ++E+ +++ + + Sbjct: 310 DTICKATSLELILGGTDSTAVTLTWALSLLLRNPLALGKAKEEIDMQIGKDEYIRESDIS 369 Query: 1187 KMKNLTMVIQETLRLYPAGAFVS-RMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWGP 1363 K+ L +++ETLRLYP F S R + LGG HI KG + + +H DP +W Sbjct: 370 KLVYLQAIVKETLRLYPPAPFSSPREFTENCILGGYHIKKGTRLIHNLWKIHRDPSVWS- 428 Query: 1364 DAKEFNPARF------SDARPQLHSYLPFGAGARTCLG 1459 D EF P RF D R LPFG+G R C G Sbjct: 429 DPLEFKPERFLTTHKDVDLRGHNFELLPFGSGRRVCAG 466
>Q9V7G5:C4AA1_DROME Probable cytochrome P450 4aa1 - Drosophila melanogaster (Fruit fly)| Length = 514 Score = 102 bits (255), Expect = 4e-21 Identities = 88/340 (25%), Positives = 156/340 (45%), Gaps = 19/340 (5%) Frame = +2 Query: 518 GRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIK 697 G G++ S+G W++ R++I P F + ++ +D VD++Q+L E +A ++ GT +I Sbjct: 130 GDGLITSSGSKWSNHRRLIQPAFHHNLLEKFIDTFVDASQSLYENLDA---EAVGT-EIN 185 Query: 698 IDDDIRAYSADVISRTCFGSSYVKGKKIFLKLRELQKAVSKPNVLAEMT-------GLRF 856 I + D+++ G K + + + K + A T G+ Sbjct: 186 IAKYVNNCVLDILNEAVLGVPIKKRGQDVAMMEDSPFRQGKIMMPARFTQPWLLLDGIYH 245 Query: 857 FPTKKNRQAWGLHKQVHRLILEIVK-----ESGEDKNLLRAIL--HSASSSKVGLGEAEN 1015 + TK K+++ ++++ ++ + N R L H S+ E Sbjct: 246 W-TKMANDELNQKKRLNDFTRKMIQRRRQIQNNNNGNSERKCLLDHMIEISESNRDFTEE 304 Query: 1016 FIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVC--GGRPLDSQSLQK 1189 IV+ + AG +S A+ L LL +PE QDR E+ + R L + Sbjct: 305 DIVNEACTFMLAGQDSVGAAVAFTLFLLTQNPECQDRCVLELATIFEDSNRAPTMTDLHE 364 Query: 1190 MKNLTMVIQETLRLYPAGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWGPDA 1369 M+ + M I+E LRLYP+ ++R +E++L +P G N++I H ++ PD Sbjct: 365 MRYMEMCIKEALRLYPSVPLIARKLGEEVRLAKHTLPAGSNVFICPYATHRLAHIY-PDP 423 Query: 1370 KEFNPARFSDARPQ---LHSYLPFGAGARTCLGQGFATAE 1480 ++F P RFS + +++LPF AG R C+G FA E Sbjct: 424 EKFQPERFSPENSENRHPYAFLPFSAGPRYCIGNRFAIME 463
>Q9VG82:CP9F2_DROME Probable cytochrome P450 9f2 - Drosophila melanogaster (Fruit fly)| Length = 516 Score = 102 bits (254), Expect = 5e-21 Identities = 98/360 (27%), Positives = 157/360 (43%), Gaps = 37/360 (10%) Frame = +2 Query: 512 LFGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLM---VDSAQTLLEPWEARVDKSGG 682 LFG + W R ++P F K++ M LM A L+ ++RV ++ Sbjct: 121 LFGSSLFSMRDARWKDMRSTLSPAFTGSKMRQMFQLMNQVAKEAVDCLKQDDSRVQEN-- 178 Query: 683 TVDIKIDDDIRAYSADVISRTCFGSSYVKGKKIFLKLRELQKAVSKPNVLAEMTGLRFFP 862 ++ + D ++ DVI+ T FG K ++ K ++ L M + FF Sbjct: 179 --ELDMKDYCTRFTNDVIASTAFGLQVNSFKDRENTFYQMGKKLTTFTFLQSMKFMLFFA 236 Query: 863 TKKNRQAWGLHKQVH-------------RLILEIVKESGEDK-------NLL---RAILH 973 K GL+K + RL+L+ +K E N+L R I+ Sbjct: 237 LK------GLNKILKVELFDRKSTQYFVRLVLDAMKYRQEHNIVRPDMINMLMEARGIIQ 290 Query: 974 SASSSKVGLGE-AENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEV 1150 + + + E ++ IV C +FAG+E++AV + L + + Q R+ +EV +V Sbjct: 291 TEKTKASAVREWSDRDIVAQCFVFFFAGFETSAVLMCFTAHELMENQDVQQRLYEEVQQV 350 Query: 1151 ---CGGRPLDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKLG----GVHIPKGV 1309 G+ L +++ MK L V+ E LR +PA V R +++ V + KG Sbjct: 351 DQDLEGKELTYEAIMGMKYLDQVVNEVLRKWPAAIAVDRECNKDITFDVDGQKVEVKKGD 410 Query: 1310 NIYIPVSTMHLDPKLWGPDAKEFNPARFSDARP---QLHSYLPFGAGARTCLGQGFATAE 1480 I++P H DPK + K F+P RFSD Q +Y PFG G R C+G FA E Sbjct: 411 VIWLPTCGFHRDPKYFENPMK-FDPERFSDENKESIQPFTYFPFGLGQRNCIGSRFALLE 469
>P33270:CP6A2_DROME Cytochrome P450 6a2 - Drosophila melanogaster (Fruit fly)| Length = 506 Score = 102 bits (254), Expect = 5e-21 Identities = 117/488 (23%), Positives = 199/488 (40%), Gaps = 41/488 (8%) Frame = +2 Query: 128 VGACSLALYLYYTVWVVPQRLLAGFRRQGIGGPRPSFPYGNMADXXXXXXXXXXXXXXXX 307 + SL YLY+ R + R+G+ P YGNM Sbjct: 9 IAISSLLAYLYH-------RNFNYWNRRGVPHDAPHPLYGNMVGFRKNR----------- 50 Query: 308 XXXIVHDYRPAVLPFYEKWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDL---- 475 ++HD+ +Y K+RK P + FLH +V D L ++ + Sbjct: 51 ---VMHDF---FYDYYNKYRKSGFPFVGF-----YFLHKPAAFIV-DTQLAKNILIKDFS 98 Query: 476 ---GKSSYLKATHEPLFGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLL 646 + + +PL + + +G+ W R+ + P F K+K M ++ ++ + Sbjct: 99 NFADRGQFHNGRDDPLT-QHLFNLDGKKWKDMRQRLTPTFTSGKMKFMFPTVIKVSEEFV 157 Query: 647 EPWEARVDKSGGTVDIKIDDDIRAYSADVISRTCFGSSY-----------VKGKKIFLKL 793 + +V + ++I + + ++ DVI FG G+K+F + Sbjct: 158 KVITEQVPAAQNGAVLEIKELMARFTTDVIGTCAFGIECNTLRTPVSDFRTMGQKVFTDM 217 Query: 794 RE---LQKAVSKPNVLAEMTGLRFFPTKKNRQAWGLHKQVHRLILEIV----KESGEDKN 952 R L V LA +R P +H+ RL+ + + +E+ + + Sbjct: 218 RHGKLLTMFVFSFPKLASRLRMRMMPED-------VHQFFMRLVNDTIALRERENFKRND 270 Query: 953 LLRAILHSASSSKVGLGEAENF-------IVDNCKSIYFAGYESTAVTAAWCLMLLGLHP 1111 + ++ +V L E + Y AG+E+++ T ++CL L + Sbjct: 271 FMNLLIELKQKGRVTLDNGEVIEGMDIGELAAQVFVFYVAGFETSSSTMSYCLYELAQNQ 330 Query: 1112 EWQDRVRQE---VLEVCGGRPLDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKL 1282 + QDR+R E VLE G+ L +S++ M L VI ETLRLY + R AL + + Sbjct: 331 DIQDRLRNEIQTVLEEQEGQ-LTYESIKAMTYLNQVISETLRLYTLVPHLERKALNDYVV 389 Query: 1283 GG---VHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARFSD---ARPQLHSYLPFGAGA 1444 G + I KG + IP H D L+ P+ + F+P RFS A + +LPFG G Sbjct: 390 PGHEKLVIEKGTQVIIPACAYHRDEDLY-PNPETFDPERFSPEKVAARESVEWLPFGDGP 448 Query: 1445 RTCLGQGF 1468 R C+G F Sbjct: 449 RNCIGMRF 456
>P12394:CP17A_CHICK Cytochrome P450 17A1 - Gallus gallus (Chicken)| Length = 508 Score = 102 bits (254), Expect = 5e-21 Identities = 107/400 (26%), Positives = 175/400 (43%), Gaps = 25/400 (6%) Frame = +2 Query: 536 SNGEAWAHQRKII--APEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDD 709 S G W QRK++ A F + + ++ A +L E A D + + + + Sbjct: 121 SYGPLWKFQRKLVHAALSMFGEGSVALEKIICREAASLCETLGAAQDMA-----LDMAPE 175 Query: 710 IRAYSADVISRTCFGSSYVKGKKIFLKLRELQKA----VSKPNVLAEMTGLRFFPTKKNR 877 + +V+ CF SSY +G F + E + V+K +++ L+ FP + Sbjct: 176 LTRAVTNVVCSLCFNSSYRRGDPEFEAMLEYSQGIVDTVAKESLVDIFPWLQIFPNRDLA 235 Query: 878 QAWGLHKQVHRLILEIVKESGED------KNLLRAILH------SASSSKVGLGEAENFI 1021 K +L+ + E E ++L+ A+L + S + GL ++ + Sbjct: 236 LLKRCLKVRDQLLQQKFTEHKEAFCGDTVRDLMDALLQVRLNAENNSPLEPGLELTDDHL 295 Query: 1022 VDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCG-GRPLDSQSLQKMKN 1198 + I+ AG E+T W ++ L +PE Q ++++E+ + G R + Sbjct: 296 LMTVGDIFGAGVETTTTVLKWAVLYLLHYPEVQKKIQEEMDQKIGLARHPHLSDRPLLPY 355 Query: 1199 LTMVIQETLRLYPAGAF-VSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWGPDAKE 1375 L I E LR+ P + ++L + +G IPKG + I + ++H D K W +E Sbjct: 356 LEATISEGLRIRPVSPLLIPHVSLADTSIGEYSIPKGARVVINLWSVHHDEKEWDKP-EE 414 Query: 1376 FNPARFSDARPQ-LHS----YLPFGAGARTCLGQGFATAEXXXXXXXXXXXFALRLSPLY 1540 FNP RF D + Q +HS YLPFGAG R CLG+ A E F L P Sbjct: 415 FNPGRFLDEQGQHIHSPSPSYLPFGAGIRVCLGEVLAKMELFLFLAWVLQRFTLE-CPQD 473 Query: 1541 QHSPALKLIVEPEFGVDITLTKVQTASTTTY*LREAMWSG 1660 Q P+L E +FGV + + K + + LREA W G Sbjct: 474 QPLPSL----EGKFGVVLQVQKFRVKAR----LREA-WRG 504
>Q9V770:C6A17_DROME Probable cytochrome P450 6a17 - Drosophila melanogaster (Fruit fly)| Length = 501 Score = 102 bits (254), Expect = 5e-21 Identities = 92/383 (24%), Positives = 175/383 (45%), Gaps = 27/383 (7%) Frame = +2 Query: 542 GEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAY 721 G+ W H R + P F K+K M ++V + + + + ++ G V +++ D + Y Sbjct: 122 GQKWRHLRHKLTPTFTSGKMKNMFPIVVKVGEEMDKVFRSKTAADRGQV-LEVVDLVARY 180 Query: 722 SADVISRTCFG---SSYVKGKKIFLKLRELQKAVSKPNVLAEMTGLRF-FPTKKNR---- 877 +ADVI FG +S K F+ + + +A+++ + F FP R Sbjct: 181 TADVIGNCAFGLNCNSLYDPKAEFVSIGK--RAITEHRYGNMLDIFLFGFPKLSRRLRLK 238 Query: 878 ----QAWGLHKQVHRLILEIVKESGEDKN-LLRAILHSASSSKVGLGE---AENFIVDNC 1033 +A + ++ R ++ + E +N + +++ + + G E N ++ Sbjct: 239 LNIQEAEDFYTKIVRETIDYRLRTKEKRNDFMDSLIEMYKNEQSGNSEDGLTFNELLAQA 298 Query: 1034 KSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCG--GRPLDSQSLQKMKNLTM 1207 + AG+E+++ T + L L + + QD++R+E+ V G + + +++MK L Sbjct: 299 FIFFVAGFETSSTTMGFALYELARNQDVQDKLREEIGNVFGKHNKEFTYEGIKEMKYLEQ 358 Query: 1208 VIQETLRLYPAGAFVSRMALQELKLGG--VHIPKGVNIYIPVSTMHLDPKLWGPDAKEFN 1381 V+ ETLR YP A ++RM + I KG + IP +H DP ++ P+ + F Sbjct: 359 VVMETLRKYPVLAHLTRMTDTDFSPEDPKYFIAKGTIVVIPALGIHYDPDIY-PEPEIFK 417 Query: 1382 PARFSD----ARPQLHSYLPFGAGARTCLGQGFATAEXXXXXXXXXXXFALRLSPLYQHS 1549 P RF+D ARP ++LPFG G R C+G F + + +SP Q Sbjct: 418 PERFTDEEIAARPSC-TWLPFGEGPRNCIGLRFGMMQTCVGLAYLIRGYKFSVSPETQIP 476 Query: 1550 PAL---KLIVEPEFGVDITLTKV 1609 + +++ E G+ + + K+ Sbjct: 477 MKIVVKNILISAENGIHLKVEKL 499
>Q9V558:CP4P1_DROME Cytochrome P450 4p1 - Drosophila melanogaster (Fruit fly)| Length = 513 Score = 102 bits (253), Expect = 7e-21 Identities = 91/355 (25%), Positives = 157/355 (44%), Gaps = 31/355 (8%) Frame = +2 Query: 509 PLFGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTV 688 P G+L S G+ W +RK++ P F + + ++ +Q L +E + + V Sbjct: 123 PFLRTGLLTSTGKKWHARRKMLTPTFHFNILNQFQEIFKTESQKFLLQFEGQDE-----V 177 Query: 689 DIKIDDDIRAYSADVISRTCFG----SSYVKGKKIFLKLRELQKAVSKPNVLAEMTGLRF 856 I + D I ++ + I T G KG + ++++ + + G + Sbjct: 178 TITLHDVIPRFTLNSICETAMGVKLDEMAEKGDRYRENFSQIEECFIRRLSNPLLWGDKL 237 Query: 857 FPTKKNRQAWGLHKQVHRLILEIVKESGEDKNLLRAILHSASSS--KVGLGEAENF---- 1018 F + VHR EI+ + ++LL+ L +SS+ G + F Sbjct: 238 FEMFAAKDFASALDVVHRFSSEII---AKRRDLLKDELDKSSSTADDDGFVSKKRFAMLD 294 Query: 1019 ---------------IVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVC 1153 I + ++ F GY++T++ + LM + L+P+ Q+ QE+ E Sbjct: 295 TLIYAEKDGLIDHIGICEEVDTLMFEGYDTTSIGLIFGLMNMSLNPDKQELCYQEIQEHI 354 Query: 1154 GG--RPLDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKL-GGVHIPKGVNIYIP 1324 LD L K+K L ++ET RL+P+ + R A+QE +L G+ +PKG I I Sbjct: 355 DDDLSNLDVGQLNKLKYLEYFMKETTRLFPSVPIMGREAVQETELANGLILPKGAQITIH 414 Query: 1325 VSTMHLDPKLWGPDAKEFNPARFSDARPQ---LHSYLPFGAGARTCLGQGFATAE 1480 V +H + K W +EF P RF Q ++Y+PF AG R C+G+ +A E Sbjct: 415 VFDIHRNAKYW-DSPEEFRPERFLPENVQDRHTYAYVPFSAGQRNCIGKKYAMQE 468
>O22307:C71DB_LOTJA Cytochrome P450 71D11 - Lotus japonicus| Length = 490 Score = 102 bits (253), Expect = 7e-21 Identities = 91/396 (22%), Positives = 173/396 (43%), Gaps = 26/396 (6%) Frame = +2 Query: 368 KEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRGILKSN-- 541 K++GP+ +G V+F+ VS + +++ + T +G + + Sbjct: 49 KKYGPLMHLQLGEVIFIIVSSAEYAKEVMKTHDVTFASRPRSLFTDIVFYGSTDIGFSPY 108 Query: 542 GEAWAHQRKIIAPEFF-LDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRA 718 G+ W RKI E + +V+ + + + + L++ R+ G+V + + I + Sbjct: 109 GDYWRQVRKICNVELLSMKRVQSLWPIREEEVKNLIQ----RIASEEGSV-VNLSQAIDS 163 Query: 719 YSADVISRTCFGSSYVKGKKIFLKLRELQKAVSKPNVLAEMTGLRFFP--TKKNRQAWGL 892 + SR+ FG Y++ ++ +RE+ K N+ ++ T+ + L Sbjct: 164 LIFTITSRSAFGKRYMEQEEFISCVREVMKLAGGFNIADLFPSAKWLENLTRMRSKFEYL 223 Query: 893 HKQVHRLILEIVKE------------SGEDKNLLRAILHSASSSKVGLGEAENFIVDNCK 1036 H+++ R++ I+ + G +++L+ +L +SS + + + N K Sbjct: 224 HQKMDRILETIIDDHKANSRTKEGQVEGGEEDLIDVLLKYENSST---DQDFHLTIRNIK 280 Query: 1037 SIYF----AGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGR-PLDSQSLQKMKNL 1201 +I F AG E++A T W + + P + + EV E+ R +D + ++K L Sbjct: 281 AILFDIFIAGSETSATTINWTMAEMMKDPILLKKAQDEVREIFQRRGKVDETCIYELKYL 340 Query: 1202 TMVIQETLRLYPAGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFN 1381 I E LRL+P G V R Q ++ G HIP + + + D K W + + F Sbjct: 341 KAFINEVLRLHPPGPLVFRECRQACEINGYHIPAKSTVLVNTFAIGTDSKYWA-EPERFC 399 Query: 1382 PARFSDA----RPQLHSYLPFGAGARTCLGQGFATA 1477 P RF D+ + +LPFGAG R C G + A Sbjct: 400 PERFIDSSIDYKGTNFEHLPFGAGRRICPGINYGMA 435
>P36423:THAS_MOUSE Thromboxane-A synthase - Mus musculus (Mouse)| Length = 533 Score = 101 bits (252), Expect = 9e-21 Identities = 106/420 (25%), Positives = 184/420 (43%), Gaps = 55/420 (13%) Frame = +2 Query: 365 RKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEP-LFGRGILKSN 541 R+ +GP+ Y +G + + +S PD+++ + V S+ + + EP + +L Sbjct: 71 RERYGPLCGYYLGRRMHVVISEPDMIKQV--LVENFSNFSNRMASGLEPKMVADSVLLLR 128 Query: 542 GEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVD-IKIDDDIRA 718 W R + F +K+ M L+ + + L+ A + + + D I Sbjct: 129 DRRWEEVRGALMSSFSPEKLDEMTPLISQACELLV----AHLKRYAASRDAFNIQRCYCC 184 Query: 719 YSADVISRTCFGSS-------------YVKGKKIFLKLRELQKAV-SKPNVLAEMTGLRF 856 Y+ DV++ FG+ + + F R L + S P+++ + R Sbjct: 185 YTIDVVASVAFGTQVDSQNSPEDPFVQHCRRASTFCIPRPLLVLILSFPSIMVPLA--RI 242 Query: 857 FPTKKNRQAWGLHKQVHRLILEIVKESGED---KNLLRAILHSASS-SKVGL-------- 1000 P K + G + R ++ + + + ++ L+ +L + S + VG+ Sbjct: 243 LPNKNRDELNGFFNTLIRNVIALRDQQAAEERRRDFLQMVLDAQHSMNSVGVEGFDMVPE 302 Query: 1001 ------------------GEAENFIVDNCKSIYF----AGYESTAVTAAWCLMLLGLHPE 1114 ++ F VD F AG+E T ++ LL HP+ Sbjct: 303 SLSSSECTKEPPQRCHPTSTSKPFTVDEIVGQAFLFLIAGHEVITNTLSFITYLLATHPD 362 Query: 1115 WQDRVRQEVLEVCGGRPL-DSQSLQK-MKNLTMVIQETLRLYPAGAFVSRMALQELKLGG 1288 Q+R+ +EV G P + SLQ+ + L MVI ETLR+YP +R A Q+ ++ G Sbjct: 363 CQERLLKEVDLFMGKHPAPEYHSLQEGLPYLDMVISETLRMYPPAFRFTREAAQDCEVLG 422 Query: 1289 VHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARF-SDARPQLH--SYLPFGAGARTCLG 1459 IP G + I V +H DP+ W P+ + F+P RF ++AR Q +YLPFGAG R+CLG Sbjct: 423 QRIPAGTVLEIAVGALHHDPEHW-PNPETFDPERFTAEARLQRRPFTYLPFGAGPRSCLG 481
>P29980:CPXN_ANASP Probable cytochrome P450 110 - Anabaena sp. (strain PCC 7120)| Length = 459 Score = 101 bits (252), Expect = 9e-21 Identities = 91/392 (23%), Positives = 175/392 (44%), Gaps = 15/392 (3%) Frame = +2 Query: 350 FYEKWRKEHGPVFTYSMGNV-VFLHVSRPDVVRDINLCVS-LDLGKSSYLKATHEPLFGR 523 F +K+ K++G +F+ + + F+ + P +++I S D+G+ + L EPL GR Sbjct: 27 FQKKYSKKYGNIFSMQLAGIGSFVILGEPQALQEIFTQDSRFDVGRGNTLA---EPLIGR 83 Query: 524 -GILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKI 700 ++ +G+ +RK++ P F ++++ + + W+ + K+ Sbjct: 84 TSLMLMDGDRHRRERKLLMPPFHGERLQAYAQQICLITNQIASEWQIGQPFVARSAMQKL 143 Query: 701 DDDIRAYSADVISRTCFGSS----YVKGKKIFLKLRELQKAVSKPNVLAEMTGLRFFPTK 868 S +VI + FG + Y + K +F + + + ++L + + + T Sbjct: 144 -------SLEVIIQIVFGLADGERYQQIKPLFTDWLNMTDSPLRSSMLFLKSLQKDWGTW 196 Query: 869 KNRQAWGLHKQVHRLILEIVKESGEDKNLLR-------AILHSASSSKVGLGEAENFIVD 1027 WG K R I ++++ E+K L A+ + G + + D Sbjct: 197 T---PWGQMKHKQRSIYDLLQAEIEEKRTKENEQRGDVLSLMMAARDENGQAMTDEELKD 253 Query: 1028 NCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGRPLDSQSLQKMKNLTM 1207 +I FAG+E+TA T AW + + Q++++QE L+ G P + + ++ LT Sbjct: 254 ELLTILFAGHETTATTIAWAFYQILKNVNVQEKLQQE-LDRLGANP-NPMEIAQLPYLTA 311 Query: 1208 VIQETLRLYPA-GAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNP 1384 V QETLR+YP R+ + + G + + + +H L+ P+ ++F P Sbjct: 312 VSQETLRMYPVLPTLFPRITKSSINIAGYQLEPDTTLMASIYLIHYREDLY-PNPQQFRP 370 Query: 1385 ARFSDARPQLHSYLPFGAGARTCLGQGFATAE 1480 RF + + Y+PFG G+R CLG A E Sbjct: 371 ERFIERQYSPSEYIPFGGGSRRCLGYALALLE 402
>P24465:C71A1_PERAE Cytochrome P450 71A1 - Persea americana (Avocado)| Length = 471 Score = 101 bits (252), Expect = 9e-21 Identities = 97/395 (24%), Positives = 173/395 (43%), Gaps = 29/395 (7%) Frame = +2 Query: 371 EHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRGILKSN--G 544 E GP+ +G++ L VS ++ +I L A + + + G Sbjct: 61 ELGPLILLHLGHIPTLIVSTAEIAEEILKTHDLIFASRPSTTAARRIFYDCTDVAFSPYG 120 Query: 545 EAWAHQRKIIAPEFF-LDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVD-IKIDDDIRA 718 E W RKI E + +V + + ++E R+ +S T + + + + + Sbjct: 121 EYWRQVRKICVLELLSIKRVNSYRSIREEEVGLMME----RISQSCSTGEAVNLSELLLL 176 Query: 719 YSADVISRTCFGSSYVKGKKIFLKLRELQKAVSKPNVLAEMTGLRFFP--------TKKN 874 S+ I+R FG Y ++ K +L A ++ +FP T + Sbjct: 177 LSSGTITRVAFGKKYEGEEERKNKFADL--ATELTTLMGAFFVGDYFPSFAWVDVLTGMD 234 Query: 875 RQAWGLHKQVHRLILEIV-------KESGED----KNLLRAILHSASSSKVGLGEAENFI 1021 + H ++ + ++ K +G D K+L+ +LH S +G+ N + Sbjct: 235 ARLKRNHGELDAFVDHVIDDHLLSRKANGSDGVEQKDLVDVLLHLQKDSSLGVHLNRNNL 294 Query: 1022 VDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGR-PLDSQSLQKMKN 1198 ++ G ++TAVT W + L HP+ ++ +QEV V G + ++ + L ++ Sbjct: 295 KAVILDMFSGGTDTTAVTLEWAMAELIKHPDVMEKAQQEVRRVVGKKAKVEEEDLHQLHY 354 Query: 1199 LTMVIQETLRLYP-AGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWGPDAKE 1375 L ++I+ETLRL+P A V R + +++ + G HIP ++I + DPK W +A+E Sbjct: 355 LKLIIKETLRLHPVAPLLVPRESTRDVVIRGYHIPAKTRVFINAWAIGRDPKSW-ENAEE 413 Query: 1376 FNPARF----SDARPQLHSYLPFGAGARTCLGQGF 1468 F P RF D + Q +PFGAG R C G F Sbjct: 414 FLPERFVNNSVDFKGQDFQLIPFGAGRRGCPGIAF 448
>Q9W011:C4D20_DROME Probable cytochrome P450 4d20 - Drosophila melanogaster (Fruit fly)| Length = 510 Score = 101 bits (252), Expect = 9e-21 Identities = 100/405 (24%), Positives = 170/405 (41%), Gaps = 41/405 (10%) Frame = +2 Query: 509 PLFGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTV 688 P G+L S G W +RKI F ++ V++M + +++ D G Sbjct: 110 PFLNDGLLVSTGRKWHARRKIFTHAFHFKVLEHYVEIMDRHSSVMVDNLRKVAD---GKT 166 Query: 689 DIKIDDDIRAYSADVISRTCFGSS----------YVKGKKIFLKLRE------------- 799 + + + + DVI+ G Y+K K + ++ Sbjct: 167 AVDMLKYVSLAALDVITEAAMGVQVNAQNDPDFPYIKALKSVVYIQPDRMFRFSRRYNWL 226 Query: 800 --LQKAVSKPNVLAEMTGLRFFPTK---------KNRQAWGLHKQVHRLILEIVKESGED 946 L + +L+++ + F K + +A G ++ + EI +S Sbjct: 227 FPLAAPLLHRQLLSDIRVMHDFTDKVISERRETVRRAKADGTYRPLSLGDAEIGSKS--- 283 Query: 947 KNLLRAILHSASSSKVGLGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDR 1126 + L IL +S + L +A+ I + + F G ++T+ + L + HPE Q R Sbjct: 284 QMALLDILLQSSINNQPLSDAD--IREEVDTFMFEGDDTTSSGVSHALYAIARHPEVQQR 341 Query: 1127 VRQEVLEVCG---GRPLDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKLGGVHI 1297 + +E+ V G P+ LQ +K L VI+ET+RLYP + R A +EL++G I Sbjct: 342 IFEELQRVLGPDASAPVTQAQLQDLKYLDCVIKETMRLYPPVPAIGRHAQKELEIGDKTI 401 Query: 1298 PKGVNIYIPVSTMHLDPKLWGPDAKEFNPARFSDARPQLH---SYLPFGAGARTCLGQGF 1468 P +IY+ + H D + PD F P RF + + Q H +Y+PF AG + C+GQ F Sbjct: 402 PANTSIYLVLYYAHRDANYF-PDPLSFRPERFLEDQEQGHNTFAYVPFSAGPKNCIGQKF 460 Query: 1469 ATAEXXXXXXXXXXXFALRLSPLYQH-SPALKLIVEPEFGVDITL 1600 A E + L PL + P L I+ G+++ L Sbjct: 461 AVLEMKVLISKVLRFY--ELLPLGEELKPMLNFILRSASGINVGL 503
>P79152:CP3AJ_CAPAE Cytochrome P450 3A19 - Capra aegagrus (Wild goat)| Length = 218 Score = 101 bits (251), Expect = 1e-20 Identities = 50/146 (34%), Positives = 86/146 (58%), Gaps = 4/146 (2%) Frame = +2 Query: 1046 FAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGR-PLDSQSLQKMKNLTMVIQET 1222 F GYE+T+ + ++ + L HP+ Q ++++E+ + P +L +M+ L MV+ ET Sbjct: 15 FGGYETTSTSLSFIIYELATHPDVQQKLQEEIDATFPNKAPPTYDALVQMEYLDMVVNET 74 Query: 1223 LRLYPAGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARFSDA 1402 LR++P + R+ +++++ GV IPKG + +P+ +H +P+ W P+ +EF P RFS Sbjct: 75 LRMFPIAGRLERLCKKDVEIHGVSIPKGTTVMVPLFVLHNNPEFW-PEPEEFRPERFSKK 133 Query: 1403 RP---QLHSYLPFGAGARTCLGQGFA 1471 + YLPFG G R C+G FA Sbjct: 134 NKDGINPYVYLPFGTGPRNCVGMRFA 159
>Q9LTL8:C71BO_ARATH Cytochrome P450 71B24 - Arabidopsis thaliana (Mouse-ear cress)| Length = 498 Score = 101 bits (251), Expect = 1e-20 Identities = 103/407 (25%), Positives = 176/407 (43%), Gaps = 37/407 (9%) Frame = +2 Query: 368 KEHGPVFTYSMGNVVFLHVSRPDV------VRDINLCVSLDLGKSSYLKATHEPLFGRGI 529 K+HGPV +G + + +S + V D+ C +S L + + Sbjct: 55 KKHGPVLLLRLGFLDMVVISSTEAAEEALKVHDLECCTRPITNVTSKLWRDGQDIG---- 110 Query: 530 LKSNGEAWAHQRKIIAPEFF-LDKVKGMVDLMVDSAQTLLEPW-EARVDKSGGTVDIKID 703 L GE+ RK+ +FF KV+ + + +++ EA + KS + + Sbjct: 111 LAPYGESLRELRKLSFLKFFSTTKVRSFRYIREEENDLMVKKLKEAALKKSS----VDLS 166 Query: 704 DDIRAYSADVISRTCFGSSYVKGKKIFL-KLRELQKAVSKPNVLAEMT----GLRFFPTK 868 + +I R+ FG + +G + K+ +L V K L+ GL +F Sbjct: 167 QTLFGLVGSIIFRSAFGQRFDEGNHVNAEKIEDLMFEVQKLGALSNSDLFPGGLGWFVDF 226 Query: 869 KNRQAWGLHK---QVHRLILEIVKESGEDKNLLRAILHSASS---------SKVGLGEAE 1012 + LHK +V L+ I+ + KN + I H K G++ Sbjct: 227 VSGHNKKLHKVFVEVDTLLNHIIDD--HLKNSIEEITHDRPDIIDSLLDMIRKQEQGDSF 284 Query: 1013 NFIVDNCKSI----YFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCG---GRPLD 1171 +DN K I Y AG +++A+T W + L +P +V+ E+ G ++ Sbjct: 285 KLTIDNLKGIIQDIYLAGVDTSAITMIWAMAELVKNPRVMKKVQDEIRTCIGIKQNEKIE 344 Query: 1172 SQSLQKMKNLTMVIQETLRLYPAG-AFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDP 1348 + K++ L +V++ETLRL+PA + R + ++K+ G +IP + + V ++ DP Sbjct: 345 EDDVDKLQYLKLVVKETLRLHPAAPLLLPRETMSQIKIQGYNIPSKTILLVNVWSIGRDP 404 Query: 1349 KLWGPDAKEFNPARFSDA----RPQLHSYLPFGAGARTCLGQGFATA 1477 K W + +EFNP RF D + LPFG+G R C G FA A Sbjct: 405 KHW-KNPEEFNPERFIDCPIDYKGNSFEMLPFGSGRRICPGIAFAIA 450
>Q9V6H1:CP9H1_DROME Probable cytochrome P450 9h1 - Drosophila melanogaster (Fruit fly)| Length = 518 Score = 100 bits (250), Expect = 1e-20 Identities = 101/419 (24%), Positives = 189/419 (45%), Gaps = 37/419 (8%) Frame = +2 Query: 335 PAVLPFYEKWRKEHG-PVF-TYSMGNVVFLHVSRPDVVRDINLCVSLD--LGKSSYLKAT 502 P + E K G PV+ Y++ + VF V P++++ I + D + +S Sbjct: 56 PVLKKMIELHTKHTGSPVYGIYALRDAVFF-VRDPELIKLIGI-KEFDHFVNHNSMHNNI 113 Query: 503 HEPLFGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKS-G 679 E + + ++ W R I+ P F K++ M DL+ ++ + + +++ S Sbjct: 114 QESILSKSLISLRDGRWKEMRNILTPAFTGSKMRIMYDLIQSCSEEGVIHIQEQLELSQD 173 Query: 680 GTVDIKIDDDIRAYSADVISRTCFG---SSYVKGKKIFLKLRELQKAVSKPNV------- 829 ++++++ D ++ DVI+ FG +S+ + F ++ + +S +V Sbjct: 174 ASIELEMKDYFTRFANDVIATVAFGISINSFRRKDNEFFRIGQAMSRISAWSVVKAMLYA 233 Query: 830 ----LAEMTGLRFFPTKKNRQAWGL------HKQVHRLIL-EIVKESGEDKNLLRAILHS 976 L ++ ++ TK L ++Q H+++ +++ E K A L Sbjct: 234 LFPRLMKVLRIQVLDTKNIDYFSSLVTAAMRYRQEHKVVRPDMIHLLMEAKQQRLADLSD 293 Query: 977 ASSSKVGLGE-AENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEV- 1150 S ++ E + ++ C +FAG+E + + + L L+P QDR+ +E++ V Sbjct: 294 KSKDELYYSEFTADDLLAQCLLFFFAGFEIISSSLCFLTHELCLNPTVQDRLYEEIISVH 353 Query: 1151 --CGGRPLDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKLGGVH------IPKG 1306 G+PL L KMK L MV+ E LR +P R Q++ L + KG Sbjct: 354 EELKGQPLTYDKLTKMKYLDMVVLEALRKWPPSISTDRECRQDIDLFDENGQKLFSARKG 413 Query: 1307 VNIYIPVSTMHLDPKLWGPDAKEFNPARFSDARP-QLHSYLPFGAGARTCLGQGFATAE 1480 + IP+ ++H DP+ + D + FNP RF+D + Y+PFG G R C+G A E Sbjct: 414 DVLQIPIFSLHHDPENF-EDPEFFNPERFADGHALESRVYMPFGVGPRNCIGNRMALME 471
>Q27594:CP6A9_DROME Cytochrome P450 6a9 - Drosophila melanogaster (Fruit fly)| Length = 504 Score = 100 bits (250), Expect = 1e-20 Identities = 101/358 (28%), Positives = 161/358 (44%), Gaps = 31/358 (8%) Frame = +2 Query: 488 YLKATHEPLFGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARV 667 Y +PL G+ L +G+ W R ++ F K+K M +V +E + + Sbjct: 108 YHNTEDDPLSGQLFLL-DGQKWKSMRSKLSYTFTSGKMKYMFPTVVKVGHEFIEVFGQAM 166 Query: 668 DKSGGTVDIKIDDDIRAYSADVISRTCFGSSYVKGKKIFLKLRELQKAVSKPNVLAEMT- 844 +KS +++ D + ++ DVI FG LK E + V + E Sbjct: 167 EKSP---IVEVRDILARFTTDVIGTCAFGIECSS-----LKDPEAEFRVMGRRAIFEQRH 218 Query: 845 ---GLRFFPTKKNRQAWGLHKQV-----HRLILEIVKESG--EDKNLLRAI--------L 970 G+ F + +N A LH ++ L IV+E+ +KN +R L Sbjct: 219 GPIGIAFINSFQNL-ARRLHMKITLEEAEHFFLRIVRETVAFREKNNIRRNDFMDQLIDL 277 Query: 971 HSASSSKVGLGEAENFIVDNCKSIYF----AGYESTAVTAAWCLMLLGLHPEWQDRVRQE 1138 ++ +K GE+ N ++ + F AG+E+++ T + L L H + QDRVR+E Sbjct: 278 KNSPLTKSESGESVNLTIEEMAAQAFVFFGAGFETSSTTMGFALYELAQHQDIQDRVRKE 337 Query: 1139 VLEVCG--GRPLDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKLGG---VHIPK 1303 EV G + +S++ M L VI ETLRLY ++R L++ ++ G I K Sbjct: 338 CQEVIGKYNGEITYESMKDMVYLDQVISETLRLYTVLPVLNRECLEDYEVPGHPKYVIKK 397 Query: 1304 GVNIYIPVSTMHLDPKLWGPDAKEFNPARFSDARPQLH---SYLPFGAGARTCLGQGF 1468 G+ + IP MH D KL+ + FNP FS R + +LPFG G R C+G F Sbjct: 398 GMPVLIPCGAMHRDEKLYA-NPNTFNPDNFSPERVKERDSVEWLPFGDGPRNCIGMRF 454
>O44221:CP4E5_DROMT Cytochrome P450 4e5, mitochondrial precursor - Drosophila mettleri| (Fruit fly) Length = 522 Score = 100 bits (250), Expect = 1e-20 Identities = 97/408 (23%), Positives = 166/408 (40%), Gaps = 31/408 (7%) Frame = +2 Query: 350 FYEKWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRGI 529 F+E W K + F +G + VS P + I +L + K H P G G+ Sbjct: 58 FFEFWHKYNKDNFRIWIGYYANILVSNPKHLEVIMNSTTL-IEKLDIYDMLH-PWLGEGL 115 Query: 530 LKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDD 709 L S G W RK+I P F + ++ +M +++ ++ + + S G I D+ Sbjct: 116 LTSKGSKWHKHRKMITPTFHFNILQDFHQVMNENSAKFIKRLK---EVSAGDNIIDFQDE 172 Query: 710 IRAYSADVISRTCFGSSYVKGKKIFLKLRELQKAVSKPNVLAEMTGLRFF-PTKKNRQAW 886 + D I T G + +K R+ V + + +R F P +++ + Sbjct: 173 THYLTLDAICDTAMGVTINAIEK-----RDTVDVVKAFKDMCHIINMRAFRPLQRSDFLY 227 Query: 887 GLHKQ------------------------VHRLILEIVKESGED---KNLLRAILHSASS 985 + VHR + G + K +L L SA+ Sbjct: 228 RFSPEYATYAKTLKTLKDFTNDIIAKRIKVHRTAAAKTNQEGSEFSRKKMLPDTLLSATI 287 Query: 986 SKVGLGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGG-- 1159 L + E I + + F G+++T A+ +L PE Q ++ +E V G Sbjct: 288 DGRPLNQQE--IYEEVSTFMFEGHDTTTSGVAFAGYILSRFPEEQRKLYEEQQAVMGNEL 345 Query: 1160 -RPLDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKLGGVHIPKGVNIYIPVSTM 1336 R Q + MK L + I+E R+YP+ F+ R ++ + G +PKG + + + + Sbjct: 346 NRDATFQEISAMKYLDLFIKEAQRVYPSVPFIGRYTDKDYNIHGTIMPKGTTLNLGIIVL 405 Query: 1337 HLDPKLWGPDAKEFNPARFSDARPQLHSYLPFGAGARTCLGQGFATAE 1480 D +++ + F P RF +P Y+PF AG R C+GQ FA E Sbjct: 406 GYDDRVF-EEPHRFYPERFEKQKPGPFEYVPFSAGPRNCIGQKFALLE 452
>O18596:C4D10_DROMT Cytochrome P450 4d10 - Drosophila mettleri (Fruit fly)| Length = 513 Score = 100 bits (250), Expect = 1e-20 Identities = 108/439 (24%), Positives = 176/439 (40%), Gaps = 42/439 (9%) Frame = +2 Query: 368 KEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRG-----IL 532 K++ F MG+ L + +P RDI + LG S L E F RG +L Sbjct: 75 KKYDGTFKLKMGSNFSLMMFQP---RDIEVV----LGSSQLLDKAVEYSFLRGWLNDGLL 127 Query: 533 KSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDI 712 S G W +RKII P F ++ ++ + L+ W+ + S + D+ Sbjct: 128 LSGGRKWHRRRKIITPAFHFRILESYDEIFDRQTRLLIHKWQQTLGHS-----FDLGHDV 182 Query: 713 RAYSADVISRTCFG----------SSYVKGKKIFLKLRELQKAVSKPNVLAEMTGLRFFP 862 ++ DVI T G S YV+ K + L K + ++T + Sbjct: 183 HLFTLDVICETAMGVSTNAQTNADSDYVRAVKTISTV--LHKRMFNIFYRFDLTYMLTPL 240 Query: 863 TKKNRQAWG-LHKQVHRLILEIVKESGEDKNLLRA-ILHSASSSKVGLGEAENF------ 1018 R+A LHK ++I++ +E LLR + + + VG F Sbjct: 241 AWAERRALNVLHKFTEKIIVQRREE------LLRGGVTQTTDGADVGAKSKMVFLDILLQ 294 Query: 1019 ------------IVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGG- 1159 I + + F G+++T+ + + L+PE Q + +E++ V G Sbjct: 295 SNIDDKPLTNLDIREEVDTFMFEGHDTTSSGITFFFYNIALYPECQRKCVEEIVSVLGKD 354 Query: 1160 --RPLDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKLGGVHIPKGVNIYIPVST 1333 P+ L + + + I+ETLR+YP+ + R LQE ++ G IP G NI I Sbjct: 355 TETPVTYDLLNNLNYMDLCIKETLRMYPSVPLLGRKVLQECEINGKIIPAGTNIGISPLF 414 Query: 1334 MHLDPKLWGPDAKEFNPARF----SDARPQLHSYLPFGAGARTCLGQGFATAEXXXXXXX 1501 + + + F P RF S + H+Y+PF AG R C+GQ FA E Sbjct: 415 LGRSEDI-SSEPNTFKPERFDVVTSAEKLNPHAYIPFSAGPRNCIGQKFAMLEIKAIAAN 473 Query: 1502 XXXXFALRLSPLYQHSPAL 1558 + + + SP L Sbjct: 474 VLRHYEIEFVGNAEESPVL 492
>Q9VRI9:CP6T1_DROME Probable cytochrome P450 6t1 - Drosophila melanogaster (Fruit fly)| Length = 529 Score = 100 bits (249), Expect = 2e-20 Identities = 89/346 (25%), Positives = 153/346 (44%), Gaps = 26/346 (7%) Frame = +2 Query: 500 THEPLFGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSG 679 T + + + + S E W KI AP F KV+ M L+ + Q L E E ++ Sbjct: 131 TCDTMGSQNLFFSKYETWRETHKIFAPFFAAGKVRNMYGLLENIGQKLEEHMEQKLS-GR 189 Query: 680 GTVDIKIDDDIRAYSADVISRTCFGSSYVKGKKIFLKLRELQKAVS--KPNVLAEMTGLR 853 ++++++ ++ D+I+ FG + + R + V+ +P L + + Sbjct: 190 DSMELEVKQLCALFTTDIIASLAFGIEAHSLQNPEAEFRRMCIEVNDPRPKRLLHLFTMF 249 Query: 854 FFPTKKNRQAWGLHKQVHR--------LILEIVKESGEDKNLLRAILHSASSSKVG--LG 1003 FFP +R L+ + + +L ESGE+++ L I ++ + Sbjct: 250 FFPRLSHRVGTHLYSEEYERFMRKSMDYVLSQRAESGENRHDLIDIFLQLKRTEPAESII 309 Query: 1004 EAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEV---LEVCGGRPLDS 1174 +F + AG+++++ T + L L + QDR+R E+ L+ R L Sbjct: 310 HRPDFFAAQAAFLLLAGFDTSSSTITFALYELAKNTTIQDRLRTELRAALQSSQDRQLSC 369 Query: 1175 QSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKL------GG--VHIPKGVNIYIPVS 1330 ++ + L V+ E LRLYP AF+ R GG + G +YI V Sbjct: 370 DTVTGLVYLRQVVDEVLRLYPPTAFLDRCCNSRTGYDLSPWNGGSPFKLRAGTPVYISVL 429 Query: 1331 TMHLDPKLWGPDAKEFNPARFSDARPQLH---SYLPFGAGARTCLG 1459 +H D + W P+ + F+P RFS + Q H +YLPFGAG R C+G Sbjct: 430 GIHRDAQYW-PNPEVFDPERFSAEQRQQHHPMTYLPFGAGPRGCIG 474
>Q9STL2:C71AL_ARATH Cytochrome P450 71A21 - Arabidopsis thaliana (Mouse-ear cress)| Length = 490 Score = 100 bits (249), Expect = 2e-20 Identities = 95/381 (24%), Positives = 160/381 (41%), Gaps = 15/381 (3%) Frame = +2 Query: 374 HGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLF--GRGI-LKSNG 544 +GP+ +G V L VS DV RDI L + S E LF GR + G Sbjct: 63 YGPLMLLHLGRVPVLVVSSADVARDI-LKTHDRVFASRPRSKLFEKLFYDGRDVAFAPYG 121 Query: 545 EAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAYS 724 E W + + +K MV + Q + ++ KS ++ + + + + + + Sbjct: 122 EYWRQIKSVCVLRLLSNK---MVTSFRNVRQEEISLMMEKIQKSS-SLQVNVSELLGSLT 177 Query: 725 ADVISRTCFGSSY---VKGKKIFLKLRELQKAVSKPNV---LAEMTGLRFFPTKKNRQAW 886 DVISR G Y K++ +L L S L + + + N+ Sbjct: 178 NDVISRIALGRKYSGETDSKELMKRLMMLMGEFSVGTYVPWLGWIDWISGLDGQLNKTGN 237 Query: 887 GLHKQVHRLILEIVKESGEDKNLLRAILHSASSSKVGLGEAENFIVDNCKSIYFAGYEST 1066 L + + +++ + V G+ + + +L +G I + AG +S+ Sbjct: 238 DLDEFLEKVVQDHVDGDGQRTDFVDVLLRIQREKSIGFEIDRLCIKAIVLDVLVAGTDSS 297 Query: 1067 AVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGR-PLDSQSLQKMKNLTMVIQETLRLYPAG 1243 W + L HPE +++EV +C G + + +Q M L VI+ET RL+P Sbjct: 298 YALMDWAMTELLRHPECLRTLQEEVRTICKGNLSVSEEDIQNMSYLKAVIKETTRLHPPL 357 Query: 1244 AFVS-RMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARFSDARPQLHS 1420 ++ ++Q++ LG HIP G + I + + WGPDA++F P R D+ Sbjct: 358 PLLAPHESIQDVILGDYHIPAGTQVMINAWAIGREAATWGPDAEKFRPERHLDSSVDFRG 417 Query: 1421 Y----LPFGAGARTCLGQGFA 1471 + +PFGAG R C FA Sbjct: 418 HNFELVPFGAGRRICPAISFA 438
>Q964R0:CP6K1_BLAGE Cytochrome P450 6k1 - Blattella germanica (German cockroach)| Length = 524 Score = 100 bits (248), Expect = 3e-20 Identities = 118/483 (24%), Positives = 206/483 (42%), Gaps = 41/483 (8%) Frame = +2 Query: 143 LALYLYYTVWVVPQRLLAGFRRQGIGGPRPSFPYGNMADXXXXXXXXXXXXXXXXXXXIV 322 +A YLYY V ++R+G+ P+P +GN I+ Sbjct: 21 VAAYLYYAV------RFTYWKRKGVVNPKPLPVFGNFLPSVLQKRSPGQ---------IL 65 Query: 323 HD-YRPAVLPFYEKWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKA 499 D Y+ A PF V Y L + P++++ + L + + A Sbjct: 66 WDIYKAAEAPF----------VGFYIFARPAIL-IKDPNIIKHV-LVKDFNAFSDRHASA 113 Query: 500 THEPLFG-RGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKS 676 G + + NG W + R ++P F ++K M L+ A+ L + + ++ Sbjct: 114 AESDTLGSQNLFTLNGAPWKYLRVKLSPTFTSGRMKKMYPLVESCAKQLQD----YLKEN 169 Query: 677 GGTVDIKIDDDIRAYSADVISRTCFG--SSYVK---------GKKIFLKLR----ELQKA 811 T I++ + Y+ DVIS FG S+ +K G+KIF R E+ Sbjct: 170 CNTKAIEVKETTAKYATDVISTCAFGIESNSLKDPNAEFREFGRKIFEFTRYRTFEVMAL 229 Query: 812 VSKPNVLAEMTG----------LR--FFPTKKNRQAWGLHKQVHRLILEIVKESG----E 943 P ++ + G LR F+ T R++ + + +L +K G E Sbjct: 230 FFSPGLVKFLNGNFFTKETTEFLRKVFWDTINFRESNKISRDDFMDLLIQLKNKGTIDNE 289 Query: 944 DKNLLRAILHSASSSKVGLGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQD 1123 D + + S + +N +V + AG+E+ A T ++ L L L P+ Q+ Sbjct: 290 DGEVTEKVDKIDKDSHLFEFTGDN-LVSQPALFFTAGFETNATTLSFTLYELSLQPDLQN 348 Query: 1124 RVRQE---VLEVCGGRPLDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKLGGVH 1294 R+R E V++ G+P + + M L MV+ ETLR YP + R+ LQ+ K+ G Sbjct: 349 RLRSEIAGVMKTSNGKPT-YEDVFGMPYLHMVVSETLRKYPPLPLLDRVCLQDYKVPGTD 407 Query: 1295 --IPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARFSD---ARPQLHSYLPFGAGARTCLG 1459 I + ++I + +H DP+ + P+ + ++P RFS+ + + ++YLPFG G C+G Sbjct: 408 LIIERDTPVFIALLGLHRDPQYY-PNPERYDPERFSEENKRQRKAYTYLPFGEGPHNCIG 466 Query: 1460 QGF 1468 F Sbjct: 467 LRF 469
>Q9W223:CP6D2_DROME Probable cytochrome P450 6d2 - Drosophila melanogaster (Fruit fly)| Length = 512 Score = 99.8 bits (247), Expect = 3e-20 Identities = 86/361 (23%), Positives = 166/361 (45%), Gaps = 38/361 (10%) Frame = +2 Query: 488 YLKATHEPLFGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARV 667 Y+ +PL + G +W + R+ + P F K+KGM + D L++ E + Sbjct: 103 YVDEDKDPL-SANLFNLRGASWRNLRQKLTPSFSSGKIKGMFGTIDDVGDKLVQHLEGAL 161 Query: 668 DKSGGTVDIKIDDDIRAYSADVISRTCFGSSYVKGKKIFLKLRELQKAVSK-PNVLAEMT 844 D+S +++I D + Y+ D+I FG + + RE+ + S+ ++L ++ Sbjct: 162 DQSD---EVEIKDVMTTYAVDIIGSVIFGLEIDSFRNPKNEFREISSSTSRDESLLLKIH 218 Query: 845 GLRFF---PTKKNRQAWGLHKQVHRLILEIVKESGE--------DKNLLRAILHSASSSK 991 + F P K G ++ + +++K + E K++L+ ++ ++ K Sbjct: 219 NMSMFICPPIAKLMNRLGYESRILTSLRDMMKRTIEFREEHNVVRKDMLQLLIRLRNTGK 278 Query: 992 VGLGEAENFIVDNCKS----------------IYFAGYESTAVTAAWCLMLLGLHPEWQD 1123 +G + + + ++ + Y AG ESTA +A+ L L ++PE Sbjct: 279 IGEDDDQVWDMETAQEQLKSMSIEKIAAQAFLFYVAGSESTAAASAFTLYELSMYPELLK 338 Query: 1124 RVRQEVLEVC---GGRPLDS---QSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKLG 1285 ++EV V +P D +++Q +K L + I ET+R YP F++R ++ + Sbjct: 339 EAQEEVDAVLMKHNLKPKDRFTYEAVQDLKFLDICIMETIRKYPGLPFLNRECTEDYPVP 398 Query: 1286 GVH--IPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARF--SDARPQLHSYLPFGAGARTC 1453 G + I KG I I + M DP ++ P+ ++P RF ++ +Y+PFG G R C Sbjct: 399 GTNHIIAKGTPILISLFGMQRDP-VYFPNPNGYDPHRFDSNNMNYDQAAYMPFGEGPRHC 457 Query: 1454 L 1456 + Sbjct: 458 I 458
>Q9VS79:CP4D8_DROME Cytochrome P450 4d8 - Drosophila melanogaster (Fruit fly)| Length = 463 Score = 99.8 bits (247), Expect = 3e-20 Identities = 97/360 (26%), Positives = 165/360 (45%), Gaps = 39/360 (10%) Frame = +2 Query: 518 GRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIK 697 G G+L S+G+ W +RKII P F ++ V++ + ++ + + G T D+ Sbjct: 69 GNGLLLSDGKVWHQRRKIITPTFHFSILEQFVEVFDQQSNICVQRLAQKAN--GNTFDVY 126 Query: 698 IDDDIRAYSADVISRTCFGSS-YVKGKK---------------------IFLKLRELQKA 811 I A + D+I+ T G+ Y + + ++L++ EL Sbjct: 127 --RSICAAALDIIAETAMGTKIYAQANESTPYAEAVNECTALLSWRFMSVYLQV-ELLFT 183 Query: 812 VSKPNVLAEMTGL----RFFPTK---KNRQAWGLHKQVHRLILEIVKESGEDKNLLRAIL 970 ++ P++ T L + F K K RQA L Q +L+ ++ G + + A+L Sbjct: 184 LTHPHLKWRQTQLIRTMQEFTIKVIEKRRQA--LEDQQSKLMDTADEDVGSKRRM--ALL 239 Query: 971 HSASSSKV-GLGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLE 1147 S V G + I + + F G+++T ++CL L HPE Q ++ +E+++ Sbjct: 240 DVLLMSTVDGRPLTNDEIREEVDTFMFEGHDTTTSALSFCLHELSRHPEVQAKMLEEIVQ 299 Query: 1148 VCG---GRPLDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKL-----GGVHIPK 1303 V G RP+ + L ++K + VI+E+LR+YP V R + K G IP Sbjct: 300 VLGTDRSRPVSIRDLGELKYMECVIKESLRMYPPVPIVGRKLQTDFKYTHSVHGDGVIPA 359 Query: 1304 GVNIYIPVSTMHLDPKLWGPDAKEFNPARFSD-ARPQLHSYLPFGAGARTCLGQGFATAE 1480 G I I + +H P+ + P+ EF P R + +R +PF AG R C+GQ FA E Sbjct: 360 GSEIIIGIFGVHRQPETF-PNPDEFIPERHENGSRVAPFKMIPFSAGPRNCIGQKFAQLE 418
>Q9STK9:C71AO_ARATH Cytochrome P450 71A24 - Arabidopsis thaliana (Mouse-ear cress)| Length = 486 Score = 99.8 bits (247), Expect = 3e-20 Identities = 99/382 (25%), Positives = 163/382 (42%), Gaps = 16/382 (4%) Frame = +2 Query: 374 HGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLF-GRGI-LKSNGE 547 +GP+ G+V L VS D +D+ K + + GR + L GE Sbjct: 62 YGPLMLLHFGSVPVLVVSSADAAKDVLKTHDRVFASRPRSKIFDKIFYNGRDVALAPYGE 121 Query: 548 AWAHQRKIIAPEFFLDK-VKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAYS 724 W + + F +K V+ D+ + ++E + R+ S + I + + + + Sbjct: 122 YWRQMKSVCVLHLFSNKMVRSFRDVRQEEISLMIE--KIRISSS---LRINLSEILVNLT 176 Query: 725 ADVISRTCFGSSYVKGKKIFLKL-RELQKAVSKPNV------LAEMTGLRFFPTKKNRQA 883 +VI R G Y GK F L + L + + + +V LA + +R + + + Sbjct: 177 NNVICRVALGRKY-GGKTDFKDLMKRLTRLLGEFSVGSYVSWLAWIDWIRGLDGQLIKIS 235 Query: 884 WGLHKQVHRLILEIVKESGEDKNLLRAILHSASSSKVGLGEAENFIVDNCKSIYFAGYES 1063 L + + R++ + V G + + +L VG I ++ ++ Sbjct: 236 NDLDEFLERVVQDHVDGDGHKNDFVDFLLTIEREKSVGFEIDRLSIKAIILDVFVGDMDT 295 Query: 1064 TAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGRP-LDSQSLQKMKNLTMVIQETLRLYPA 1240 T W + L H E DR+++EV VC + + LQ MK L VI+ETLRL+P Sbjct: 296 TYTLLEWAMTELLCHHECLDRLQEEVRMVCKDKSGVSEDDLQDMKYLKAVIKETLRLHPP 355 Query: 1241 -GAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPAR----FSDAR 1405 V + ++KL HIP G ++ I + + WGPDA+EF P R + D R Sbjct: 356 LPLMVPHESTHDVKLRDYHIPAGTHVMINAWAIGREAATWGPDAEEFRPERHLNSYVDYR 415 Query: 1406 PQLHSYLPFGAGARTCLGQGFA 1471 Q +PFGAG R C FA Sbjct: 416 GQDTELVPFGAGRRICPAISFA 437
>Q9V4I1:CP9B2_DROME Cytochrome P450 9b2 - Drosophila melanogaster (Fruit fly)| Length = 505 Score = 99.4 bits (246), Expect = 4e-20 Identities = 100/429 (23%), Positives = 186/429 (43%), Gaps = 34/429 (7%) Frame = +2 Query: 350 FYEKWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRGI 529 FYE+ R +H V ++M + ++ P++++ + + +++ LF + Sbjct: 62 FYERTR-QHKLVGFFNM-RTPMITLNDPELIKKVCVKDFDHFPNHQPFITSNDRLFNDML 119 Query: 530 LKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDD 709 + W H R + P F K++ M LM +S L+ ++ G ++D Sbjct: 120 SVMRDQRWKHMRNTLTPVFTAAKMRNMFTLMNESFAECLQHLDSSSKTLPGRKGFEVDMK 179 Query: 710 IRA--YSADVISRTCFG---SSYVKGKKIFLKLRELQKAVSKPNVLAEMTGLRFFPTKKN 874 + S D+I+ T FG +SY K F ++ + L GL+FF + Sbjct: 180 VMCNKLSNDIIATTAFGLKVNSYDNPKNEFYEIGQS---------LVFSRGLQFFKFMLS 230 Query: 875 RQAWGLHKQVH-------------RLILEIV----KESGEDKNLLRAILHSASSSKVGLG 1003 L + RL++E + K + ++++ ++ + + S+ Sbjct: 231 TLVPKLFSLLKLTIFDSAKVDYFARLVVEAMQYREKHNITRPDMIQLLMEAKNESEDKWT 290 Query: 1004 EAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEV---CGGRPLDS 1174 + E IV C +FA +E+ + L +P+ Q+R+ +E++E G PL Sbjct: 291 DDE--IVAQCFIFFFAAFENNSNLICTTTYELLYNPDVQERLYEEIVETKKALNGAPLTY 348 Query: 1175 QSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKLGGVHIPK------GVNIYIPVSTM 1336 ++QKM + MVI E+LR + A R+ ++ L K G I IP+S + Sbjct: 349 DAVQKMTYMDMVISESLRKWTLAAATDRLCSKDYTLTDDDGTKLFDFKVGDRINIPISGL 408 Query: 1337 HLDPKLWGPDAKEFNPARFSDARP---QLHSYLPFGAGARTCLGQGFATAEXXXXXXXXX 1507 HLD + + P+ ++F+P RFS+ R ++YLPFG G R C+G +A + Sbjct: 409 HLDDRYF-PEPRKFDPDRFSEERKGDMVPYTYLPFGVGPRNCIGNRYALMQVKGMLFNLL 467 Query: 1508 XXFALRLSP 1534 + + SP Sbjct: 468 LHYKIEASP 476
>Q95031:CP6B6_HELAM Cytochrome P450 6B6 - Helicoverpa armigera (Cotton bollworm)| (Heliothis armigera) Length = 504 Score = 99.4 bits (246), Expect = 4e-20 Identities = 117/468 (25%), Positives = 196/468 (41%), Gaps = 26/468 (5%) Frame = +2 Query: 143 LALYLYYTVWVVPQRLLAGFRRQGIGGPRPSFPYGNMADXXXXXXXXXXXXXXXXXXXIV 322 ++LY Y+T R ++++ + GP P+ +GN+ D +V Sbjct: 15 VSLYFYFT------RTFNYWKKRNVRGPEPTVFFGNLKDSALPRKNMG----------VV 58 Query: 323 HDYRPAVLPFYEKWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKAT 502 + + P E + Y M + L V +V++ I + ++ ++ + Sbjct: 59 MEELYNMFP-------EEKVIGIYRMTSPCLL-VRDLEVIKHI-MIKDFEVFSDRGVEFS 109 Query: 503 HEPLFGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGG 682 E L G + ++GE W R P F K K M LM + A ++ A +K+ Sbjct: 110 KEGL-GSNLFHADGETWRALRNRFTPIFTSGKPKNMFYLMHEGADNFIDHVSAECEKNQ- 167 Query: 683 TVDIKIDDDIRAYSADVISRTCFGSSYVKGKKIFLKLRELQKAVSKPNVLAEMT------ 844 + ++ ++ Y+ I+ FG SY L + K +S+P+ E+ Sbjct: 168 --EFEVHSLLQTYTMSTIAACAFGISYDSIGDKVKALDIVDKIISEPSYAIELDMMYPGL 225 Query: 845 ----GLRFFPTKKNRQAWGLHKQVHRLILEIVKESGE----DKNLLRAILHSASSSKVGL 1000 L FPT L + + K SG D L L +S+K G Sbjct: 226 LSKLNLSIFPTAVKNFFKSLVDNI--VAQRNGKPSGRNDFMDLILELRQLGEVTSNKYGS 283 Query: 1001 GEAENFIVDN--CKS---IYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGRP 1165 + I D C Y AGYE++A T A+ + L L P+ Q+++ EV EV Sbjct: 284 SASSLEITDEVICAQAFVFYIAGYETSATTMAYMIYQLALSPDIQNKLIAEVDEVLKAND 343 Query: 1166 --LDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKLGG--VHIPKGVNIYIPVST 1333 + ++++MK + ETLR+Y + R A ++ K+ G V I K + I Sbjct: 344 GKVTYDTVKEMKYMNKAFDETLRMYSIVEPLQRKATRDYKIPGTDVVIEKDTIVLISPRG 403 Query: 1334 MHLDPKLWGPDAKEFNPARF-SDARPQLH--SYLPFGAGARTCLGQGF 1468 +H DPK + + K+FNP RF ++ + H +YLPFG G R C+G F Sbjct: 404 IHYDPKYYD-NPKQFNPDRFDAEEVGKRHPCAYLPFGLGQRNCIGMRF 450
>Q9V4U7:C6A14_DROME Probable cytochrome P450 6a14 - Drosophila melanogaster (Fruit fly)| Length = 509 Score = 99.4 bits (246), Expect = 4e-20 Identities = 95/371 (25%), Positives = 166/371 (44%), Gaps = 41/371 (11%) Frame = +2 Query: 479 KSSYLKATHEPLFGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWE 658 + ++ +PL G + GE W R + P F K+K M ++VD L + + Sbjct: 102 RGAFTNPRDDPLTGH-LFALEGEEWRAMRHKLTPVFTSGKIKQMSKVIVDVGLRLGDAMD 160 Query: 659 ARVDKSG---GTVDIKIDDDIRAYSADVISRTCFGSSY-----------VKGKKIFLKLR 796 V ++ G V+IK D ++ DVI FG KG++IF + R Sbjct: 161 KAVKEAKVEEGNVEIK--DLCARFTTDVIGSCAFGLECNSLQDPSAEFRQKGREIFTRRR 218 Query: 797 E---LQKAVSKPNVLAEMTGLRFFP---------TKKNRQAWGLHKQVHR--LILEIVKE 934 +Q + LA ++ P T KN + L + R I ++++ Sbjct: 219 HSTLVQSFIFTNARLARKLRIKVLPDDLTQFFMSTVKNTVDYRLKNGIKRNDFIEQMIEL 278 Query: 935 SGEDKNLLRA-----ILHSASSSKVGLGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLL 1099 ED+ + + H + ++ A+ F+ + AG+E+++ T + CL L Sbjct: 279 RAEDQEAAKKGQGIDLSHGLTLEQMA---AQAFV------FFVAGFETSSSTMSLCLYEL 329 Query: 1100 GLHPEWQDRVRQEVLEVCG---GRPLDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQ 1270 L P+ Q R+R+E+ V G L+ L +M L V+ ETLR +P + R + Sbjct: 330 ALQPDIQQRLREEIESVLANVDGGELNYDVLAQMTYLDQVLSETLRKHPLLPHLIRETTK 389 Query: 1271 ELKL--GGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARFSDARPQLH---SYLPFG 1435 + ++ + + KG+ IPV +H DP+++ P+ ++F+P+RF + +YLPFG Sbjct: 390 DYQIPNSDIVLDKGILALIPVHNIHHDPEIY-PEPEKFDPSRFDPEEVKNRHPMAYLPFG 448 Query: 1436 AGARTCLGQGF 1468 G R C+G F Sbjct: 449 DGPRNCIGLRF 459
>Q9STK7:C71AQ_ARATH Cytochrome P450 71A26 - Arabidopsis thaliana (Mouse-ear cress)| Length = 489 Score = 99.0 bits (245), Expect = 6e-20 Identities = 93/402 (23%), Positives = 167/402 (41%), Gaps = 16/402 (3%) Frame = +2 Query: 374 HGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRGILKSN--GE 547 +GP+ G V L VS ++ RD+ K + L+ + + S GE Sbjct: 62 YGPLMLLHFGRVPVLVVSSAELARDVLKTHDRVFASRPRSKIFEKLLYDKHDVASAPYGE 121 Query: 548 AWAHQRKIIAPEFFLDK-VKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAYS 724 W + + F +K V+ ++ + ++E + ++ + + + + + Sbjct: 122 YWRQMKSVCVLHLFSNKMVRSFREVREEEISLMMEKIRKSI-----SLPVNLSKILVSLT 176 Query: 725 ADVISRTCFGSSYVKGKKIFLKLRE-LQKAVSKPNV------LAEMTGLRFFPTKKNRQA 883 DVI + G Y G+ F +L E L K + +V LA + +R + + A Sbjct: 177 NDVICKVALGRKY-GGETDFKELMERLNKLLGTFSVGSYVPWLAWIDWIRGLDCQLEKTA 235 Query: 884 WGLHKQVHRLILEIVKESGEDKNLLRAILHSASSSKVGLGEAENFIVDNCKSIYFAGYES 1063 + K R++ + V + + + + +L VG I +++ G ++ Sbjct: 236 NDVDKFFERVVQDHVDGNRDMTDFVDVLLAIQRDKTVGFEINRVSIKAIVMNVFVGGTDT 295 Query: 1064 TAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGRP-LDSQSLQKMKNLTMVIQETLRLYPA 1240 ++ W + L HP+ R+++EV +C + + + +Q M L VI+E LRL+P Sbjct: 296 SSTLMEWAMTELLRHPKCLKRLQEEVRTICKDKSSVSEEEIQNMSYLKAVIKEALRLHPP 355 Query: 1241 -GAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARFSDA----R 1405 V + Q+++LG HIP G + I + + WGPD +EF P R D+ R Sbjct: 356 LPLMVPHESTQDVRLGDHHIPAGTQVLINAWAIGREAATWGPDVEEFRPERHLDSSVDYR 415 Query: 1406 PQLHSYLPFGAGARTCLGQGFATAEXXXXXXXXXXXFALRLS 1531 Q +PFG+G R C FA F RLS Sbjct: 416 GQAFELIPFGSGRRICPAISFAVVLNEVVLANLVHRFDWRLS 457
>Q9AXM6:T10H_TAXCU Taxane 10-beta-hydroxylase - Taxus cuspidata (Japanese yew)| Length = 497 Score = 98.6 bits (244), Expect = 7e-20 Identities = 64/223 (28%), Positives = 111/223 (49%), Gaps = 15/223 (6%) Frame = +2 Query: 857 FPTKKNRQAWGLHKQVHRLILEIVKE---------SGEDKNLLRAILHSASSSKVGLGEA 1009 FP + R+ ++ ++ ++K + +D++LL +L + G Sbjct: 233 FPGTRYRKGLQARLKLDEILSSLIKRRRRDLRSGIASDDQDLLSVLL--TFRDEKGNSLT 290 Query: 1010 ENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCG----GRPLDSQ 1177 + I+DN +++ A Y++T A LL +PE+ ++V QE LE+ G G + + Sbjct: 291 DQGILDNFSAMFHASYDTTVAPMALIFKLLYSNPEYHEKVFQEQLEIIGNKKEGEEISWK 350 Query: 1178 SLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLW 1357 L+ MK +QE+LR+YP + R A+ ++ G IPKG + T HL + + Sbjct: 351 DLKSMKYTWQAVQESLRMYPPVFGIFRKAITDIHYDGYTIPKGWRVLCSPYTTHLREEYF 410 Query: 1358 GPDAKEFNPARFSDARPQL--HSYLPFGAGARTCLGQGFATAE 1480 P+ +EF P+RF D + ++Y+PFG G RTC G F+ E Sbjct: 411 -PEPEEFRPSRFEDEGRHVTPYTYVPFGGGLRTCPGWEFSKIE 452
>P70085:CP17A_ORYLA Cytochrome P450 17A1 - Oryzias latipes (Medaka fish) (Japanese| ricefish) Length = 517 Score = 98.6 bits (244), Expect = 7e-20 Identities = 103/388 (26%), Positives = 164/388 (42%), Gaps = 30/388 (7%) Frame = +2 Query: 551 WAHQRKII--APEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAYS 724 W RKI+ A F + + ++ AQ+L + + + + + ++ Sbjct: 126 WRFHRKIVHGALCMFGEGSASLQRIICTEAQSLCSTLS---EAAATGLALDLSPELTRAV 182 Query: 725 ADVISRTCFGSSYVKGKKIFLKLRELQKA----VSKPNVLAEMTGLRFFPTKKNR---QA 883 +VI CF SSY +G F + + V+K +++ L+ FP K R Q Sbjct: 183 TNVICSLCFNSSYSRGDPEFEAMLRYSQGIVDTVAKDSLVDIFPWLQIFPNKDLRLLKQC 242 Query: 884 WGLHKQVHRLILEIVKESGED---KNLLRAILHSASS----------SKVGLGEAENFIV 1024 + Q+ + E K D ++LL A+L + S S +G +++ ++ Sbjct: 243 VAVRDQLLQKKFEEHKSDYSDHVQRDLLDALLRAKRSAENNNTAAEFSAEAVGLSDDHLL 302 Query: 1025 DNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCG-GRPLDSQSLQKMKNL 1201 I+ AG E+T W + L +PE Q ++++E+ G RP + L Sbjct: 303 MTVGDIFGAGVETTTTVLKWAITYLIHYPEVQKQIQEELDRKVGVDRPPQLSDRGSLPFL 362 Query: 1202 TMVIQETLRLYP-AGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLW-GPDAKE 1375 I+E LR+ P A + +AL + LG + KG + I + ++H D K W PD Sbjct: 363 EATIREVLRIRPVAPLLIPHVALSDTSLGDFTVRKGTRVVINLWSLHHDEKEWTNPDL-- 420 Query: 1376 FNPARFSDARPQL-----HSYLPFGAGARTCLGQGFATAEXXXXXXXXXXXFALRLSPLY 1540 FNP RF A SYLPFGAG R CLG+ A E F L + P Sbjct: 421 FNPGRFLSADGSSLTLPSSSYLPFGAGLRVCLGEALAKMELFLFLSWILQRFTLSVPP-S 479 Query: 1541 QHSPALKLIVEPEFGVDITLTKVQTAST 1624 Q P+L E +FGV + K +T Sbjct: 480 QSLPSL----EGKFGVVLQPVKYAVKAT 503
>Q9LTM2:C71BL_ARATH Cytochrome P450 71B21 - Arabidopsis thaliana (Mouse-ear cress)| Length = 499 Score = 98.2 bits (243), Expect = 1e-19 Identities = 99/401 (24%), Positives = 174/401 (43%), Gaps = 32/401 (7%) Frame = +2 Query: 353 YEKWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRGI- 529 + K +E+GPV G V + S + ++ L+ L AT LF Sbjct: 52 FYKLSQEYGPVMFLRFGVVPVVVFSTKEAAEEVLKTHDLETCTRPKLSATG--LFTYNFK 109 Query: 530 ---LKSNGEAWAHQRKIIAPEFFLDK-VKGMVDLMVDSAQTLLEPWEARVDKSGGTVD-I 694 GE W RK+ E F K +K + + ++ L++ +V +S T + Sbjct: 110 DIGFAQYGEDWREMRKLAMLELFSSKKLKAFRYIREEESELLVK----KVTESAQTQTLV 165 Query: 695 KIDDDIRAYSADVISRTCFGSSYVKGKKIFLKLRELQKAVSKPNV-LAEMTGLRFFPTKK 871 + + +Y+A ++ R FG ++ + F+ + ++++ V + L + FFP Sbjct: 166 DLRKALFSYTASIVCRLAFGQNFHECD--FVDMDKVEELVLESETNLGSFAFIDFFPAGL 223 Query: 872 N---RQAWGLHKQVHRLILEIVK-------------ESGEDKNLLRAILHSASS-SKVGL 1000 + G H ++H+ + +S + +++ +L + SKVG Sbjct: 224 GWAIDRISGQHSRLHKAFARLSNFFQHVIDDHLKPWQSEDHSDIVGVMLDMINKESKVGS 283 Query: 1001 GEAE-NFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGG--RPLD 1171 + + + ++ AG + A+T W L L HP +++QE+ E+ G + Sbjct: 284 FKVTYDHLKGVMSDVFLAGVNAGAITMIWALTELTRHPRVMKKLQQEIRELLGDNKEKIT 343 Query: 1172 SQSLQKMKNLTMVIQETLRLY-PAGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDP 1348 Q L+K+ L +VIQET RL+ PA + R + ++K+ G +IPK I I + DP Sbjct: 344 EQDLEKVHYLKLVIQETFRLHPPAPLLLPRETMSDVKIQGYNIPKNTMIEINTYAIGRDP 403 Query: 1349 KLWGPDAKEFNPARFSDA----RPQLHSYLPFGAGARTCLG 1459 W + EF P RF D+ + Q LPFG G R C G Sbjct: 404 NCW-TNPNEFIPERFVDSPIDYKGQHFELLPFGGGRRICPG 443
>Q9STK8:C71AP_ARATH Cytochrome P450 71A25 - Arabidopsis thaliana (Mouse-ear cress)| Length = 490 Score = 98.2 bits (243), Expect = 1e-19 Identities = 95/385 (24%), Positives = 164/385 (42%), Gaps = 17/385 (4%) Frame = +2 Query: 368 KEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRGILKSN-- 541 + +GP+ +G V L VS D+ ++I K + + L+ + S Sbjct: 59 RRYGPLMLLHLGRVPVLIVSSADMAQEILKTHDQAFANRPRSKLSQKLLYNNRDVASAPY 118 Query: 542 GEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAY 721 GE W + + +K MV D + + A++ KS ++ + + Sbjct: 119 GEYWRQMKSVCVIHLLSNK---MVRSFRDVREEEITLMMAKIRKSS-SLPFNVSKVLECL 174 Query: 722 SADVISRTCFGSSY---VKGKKIFLKLRELQKAVSKPNV---LAEMTGLRFFPTKKNRQA 883 + DVI R G Y KK+ +L EL S + LA + +R + + ++ Sbjct: 175 TNDVICRVALGRKYGGETDFKKLTDRLSELLGTFSIGSFVPWLAWVDWIRGWDAQLDKMG 234 Query: 884 WGLHKQVHRLILEIVKESGEDKN---LLRAILHSASSSKVGLGEAENFIVDNCKSIYFAG 1054 L +++ + E G+ ++ L+ A+L G I ++ G Sbjct: 235 KDLDDFFEKVVQD--HEDGDRRDGTDLIDALLRVKREKSPGFEIERVSIKAITLDVFVGG 292 Query: 1055 YESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGRPLDSQS-LQKMKNLTMVIQETLRL 1231 +++ W + L HP+ +R+++EV +C G+ S+ +Q MK L VI+E LRL Sbjct: 293 SDTSFTLLEWAMTELLRHPKSLNRLQEEVRTICKGKSRVSEDDIQGMKYLKAVIKEALRL 352 Query: 1232 YPAGAFVS-RMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARFSDA-- 1402 +P ++ + +++KL HIP G + + + + WGPDA+EF P R D Sbjct: 353 HPPFPMMAPHESTEDVKLRDYHIPAGTQVMMNAWAIGREVATWGPDAEEFKPERHLDTSV 412 Query: 1403 --RPQLHSYLPFGAGARTCLGQGFA 1471 R Q LPFGAG R C FA Sbjct: 413 DFRGQNFELLPFGAGRRICPAVSFA 437
>O49342:C71AD_ARATH Cytochrome P450 71A13 - Arabidopsis thaliana (Mouse-ear cress)| Length = 497 Score = 98.2 bits (243), Expect = 1e-19 Identities = 83/385 (21%), Positives = 158/385 (41%), Gaps = 19/385 (4%) Frame = +2 Query: 374 HGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRG--ILKSNGE 547 +GP+ G V L VS + +++ KA H + G + GE Sbjct: 64 YGPLMLLHFGRVPILVVSSGEAAQEVLKTHDHKFANRPRSKAVHGLMNGGRDVVFAPYGE 123 Query: 548 AWAHQRKIIAPEFFLDK-VKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAYS 724 W + + +K V+ + D ++E E S + + Sbjct: 124 YWRQMKSVCILNLLTNKMVESFEKVREDEVNAMIEKLEKASSSSSSE---NLSELFITLP 180 Query: 725 ADVISRTCFGSSYVK---GKKIFLKLRELQKAVSK------PNVLAEMTGLRFFPTKKNR 877 +DV SR G + + + + ++R++ + + + +LA + G+R F K Sbjct: 181 SDVTSRVALGRKHSEDETARDLKKRVRQIMELLGEFPIGEYVPILAWIDGIRGFNNKIKE 240 Query: 878 QAWGLHKQVHRLILEIVKESGEDKNLLRAILHSASSSKVGLGEAENFIVDNCKSIYFAGY 1057 + G + +++ E ++ S + + + +L G N I ++ G Sbjct: 241 VSRGFSDLMDKVVQEHLEASNDKADFVDILLSIEKDKNSGFQVQRNDIKFMILDMFIGGT 300 Query: 1058 ESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCG--GRPLDSQSLQKMKNLTMVIQETLRL 1231 +T+ W + L P+ +++ E+ G + + ++ MK L VI+E LRL Sbjct: 301 STTSTLLEWTMTELIRSPKSMKKLQDEIRSTIRPHGSYIKEKEVENMKYLKAVIKEVLRL 360 Query: 1232 YPAGAFV-SRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARFSDARP 1408 +P+ + R+ +++K+ G +I G + I + D +WGPDA+EF P R D+ Sbjct: 361 HPSLPMILPRLLSEDVKVKGYNIAAGTEVIINAWAIQRDTAIWGPDAEEFKPERHLDSGL 420 Query: 1409 QLH----SYLPFGAGARTCLGQGFA 1471 H +Y+PFG+G R C G A Sbjct: 421 DYHGKNLNYIPFGSGRRICPGINLA 445
>P43083:CP52V_CANAP Cytochrome P450 52E1 - Candida apicola (Yeast)| Length = 519 Score = 97.8 bits (242), Expect = 1e-19 Identities = 87/354 (24%), Positives = 152/354 (42%), Gaps = 31/354 (8%) Frame = +2 Query: 512 LFGRGILKSNGEAWAHQRKIIAPEF------FLDKVKGMVDLMVDSAQTLLEPWEARVDK 673 L G GI +G+ W H R ++ P+F L+ ++ ++LM+++ + +A+ Sbjct: 125 LLGNGIFTLSGDGWKHSRALLRPQFSREQVSHLESMRTHINLMINNHFKGGQVVDAQALY 184 Query: 674 SGGTVDIKID----DDIRAYSADVISRTCFGSSYVKGKKIFLKLRELQKAVSKPNVLAEM 841 T+D + + D+ + G + + F + + V+ Sbjct: 185 HNLTIDTATEFLFGESTNTLDPDLAQQGLPGPKGLVTGEQFAEAFTSALEILSVRVIVGA 244 Query: 842 TGLRFFPTKKNRQAWGLHKQVHRLILEIV-----KESGEDKNL-LRAILHSASSSKVGLG 1003 + K R H + + + + K+ D+ + +R + S +V Sbjct: 245 AWFLIWTPKFWRSCKVCHNFIDYFVYKALATPMEKDQEADRYVFIRELTKETSDPRV--- 301 Query: 1004 EAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGRPLDSQSL 1183 I D +I AG ++TA ++ LG +PE +R+ VL G +++ + Sbjct: 302 -----IRDQALNILLAGRDTTAGLLSFITYYLGAYPEVYAELREAVLSEFGSTDVETPTF 356 Query: 1184 QKMKN---LTMVIQETLRLYPAGAFVSRMALQELKL---GG------VHIPKGVNIYIPV 1327 +++K L VI+E LRL+P R A+ + KL GG V +PKG N++ Sbjct: 357 EQLKQCKVLQNVIREVLRLHPNVPLNFRQAIVDTKLPTGGGPNGDQPVFVPKGQNVFYST 416 Query: 1328 STMHLDPKLWGPDAKEFNPARFSDARPQLHS---YLPFGAGARTCLGQGFATAE 1480 +M +WGPDA F P R+++ R L S Y+PF G R CLGQ FA E Sbjct: 417 YSMQRRTDIWGPDATTFRPDRWNEPREALASGWDYIPFNGGPRICLGQQFALTE 470
>Q9VLZ7:C4D21_DROME Probable cytochrome P450 4d21 - Drosophila melanogaster (Fruit fly)| Length = 511 Score = 97.8 bits (242), Expect = 1e-19 Identities = 92/380 (24%), Positives = 165/380 (43%), Gaps = 44/380 (11%) Frame = +2 Query: 473 LGKSSYLKATH-----EPLFGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQ 637 L S+ LK H G G+L S G W +RK++AP F ++ V++M ++ Sbjct: 93 LSSSTLLKKAHLYRFLRDFLGDGLLLSTGNKWTSRRKVLAPAFHFKCLENFVEIMDRNSG 152 Query: 638 TLLEPWEARVDKSGGTVDIKIDDDIRAYSADVISRTCFGSS----------YVKGKK--I 781 ++E + D G + + + + DV + T G Y K K + Sbjct: 153 IMVEKLKNYAD---GKTCVDLFKFVSLEALDVTTETAMGVQVNAQNEPNFPYTKALKSVV 209 Query: 782 FLKLRELQKAVSKPNVLAEMTG-------------LRFFPTKKNRQAWGLHKQVHR---- 910 +++ + L + N L + ++ F K R+ + ++ Sbjct: 210 YIESKRLASVSMRYNWLFPLAAPLVYRRLQKDIAIMQDFTDKVIRERRAILERARADGTY 269 Query: 911 --LILEIVKESGEDKNLLRAILHSASSSKVGLGEAENFIVDNCKSIYFAGYESTAVTAAW 1084 LI+ G+ K L IL A+ L + + I + FAG ++T + Sbjct: 270 KPLIMGDDDIGGKAKMTLLDILLQATIDNKPLSDVD--IREEVDVFIFAGDDTTTSGVSH 327 Query: 1085 CLMLLGLHPEWQDRVRQEVLEVCGGRP---LDSQSLQKMKNLTMVIQETLRLYPAGAFVS 1255 L + HP+ Q+ + +E++ V G P + L ++K L VI+ET+RL+P + Sbjct: 328 ALHAISRHPKVQECIYEELVSVLGPDPDASVTQTKLLELKYLDCVIKETMRLHPPVPILG 387 Query: 1256 RMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARFSDAR-----PQLHS 1420 R ++LK+G + IP +I + ++ DP+ + PD F P R+ D + P L + Sbjct: 388 RYIPEDLKIGEITIPGNTSILLMPYYVYRDPEYF-PDPLVFKPERWMDMKTTSNTPPL-A 445 Query: 1421 YLPFGAGARTCLGQGFATAE 1480 Y+PF +G + C+GQ FA + Sbjct: 446 YIPFSSGPKNCIGQKFANLQ 465
>Q9LTM3:C71BK_ARATH Cytochrome P450 71B20 - Arabidopsis thaliana (Mouse-ear cress)| Length = 502 Score = 97.4 bits (241), Expect = 2e-19 Identities = 104/415 (25%), Positives = 179/415 (43%), Gaps = 44/415 (10%) Frame = +2 Query: 368 KEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRGILKSN-- 541 + +GPV G V VS + ++ LD + L G +L N Sbjct: 59 ERYGPVMLLHFGFVPVTVVSSREAAEEVLRTHDLDC-------CSRPKLVGTRLLSRNFK 111 Query: 542 -------GEAWAHQRKIIAPEFF-LDKVKGMVDLMVDSAQTLLEPW-EARVDKSGGTVDI 694 G W +RK E F L KV+ + + L++ E+ V++S + Sbjct: 112 DVCFTPYGNEWKARRKFALRELFCLKKVQSFRHIREEECNFLVKQLSESAVNRS----PV 167 Query: 695 KIDDDIRAYSADVISRTCFGSSYVKGKKIFLKLRELQKAVSKPNV-LAEMTGLRFFPTKK 871 + + +A + R G ++ + F+ ++++ V + LA T FFP Sbjct: 168 DLSKSLFWLTASIFFRVALGQNFHESN--FIDKEKIEELVFEAETALASFTCSDFFPVAG 225 Query: 872 NRQAW------GLHKQVHRLILEIVK-------------ESGEDKNLLRAILHSASSSKV 994 W G HK+++ + ++ S E ++++ ++L + K Sbjct: 226 --LGWLVDWFSGQHKRLNDVFYKLDALFQHVIDDHLNPGRSKEHEDIIDSMLDAIH--KE 281 Query: 995 GLGEAENFIVDNCK----SIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGR 1162 G + I+D+ K +I+ AG ++ A+T W + L +P+ +V+ E+ E G Sbjct: 282 GKDSSLELIIDHIKGFLANIFLAGIDTGALTMIWAMTELVKNPKLIKKVQGEIREQLGSN 341 Query: 1163 P--LDSQSLQKMKNLTMVIQETLRLYPAGAFV-SRMALQELKLGGVHIPKGVNIYIPVST 1333 + + + K+ L MVI+ET RL+PA + R + +K+ G IP I + VS Sbjct: 342 KARITEEDIDKVPYLKMVIKETFRLHPAAPLILPRETMAHIKVQGYDIPPKRRILVNVSA 401 Query: 1334 MHLDPKLWGPDAKEFNPARFSDA----RPQLHSYLPFGAGARTCLG--QGFATAE 1480 + DPKLW + +EF+P RF D+ R Q + LPFG+G R C G G A E Sbjct: 402 IGRDPKLW-TNPEEFDPERFMDSSVDYRGQHYELLPFGSGRRICPGMPMGIAAVE 455
>Q9LTM4:C71BJ_ARATH Cytochrome P450 71B19 - Arabidopsis thaliana (Mouse-ear cress)| Length = 502 Score = 97.4 bits (241), Expect = 2e-19 Identities = 104/410 (25%), Positives = 177/410 (43%), Gaps = 39/410 (9%) Frame = +2 Query: 368 KEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRGI----LK 535 + +GPV G V VS + ++ LD L T L R Sbjct: 59 ERYGPVMLLHFGFVPITVVSSREAAEEVLRTHDLDCCSRPKLVGTR--LLSRDFKDIGFT 116 Query: 536 SNGEAWAHQRKIIAPEFF-LDKVKGMVDLMVDSAQTLLEPW-EARVDKSGGTVDIKIDDD 709 G W +RK E F L KV+ + + L++ E+ VD+S + + Sbjct: 117 PYGNEWKARRKFALRELFCLKKVQSFRHIREEECNFLVKQLSESAVDRS----PVDLSKS 172 Query: 710 IRAYSADVISRTCFGSSYVKGKKIFLKLRELQKAVSKPNV-LAEMTGLRFFPTKKNRQAW 886 + +A ++ R G ++ + F+ ++++ V + LA T FFP W Sbjct: 173 LFWLTASILFRVALGQNFHESD--FIDKEKIEELVFEAETALASFTCSDFFPVAG--LGW 228 Query: 887 ------GLHKQVHRLILEIVK-------------ESGEDKNLLRAILHSASSSKVGLGEA 1009 G HK+++ + ++ S E ++++ ++L K G + Sbjct: 229 LVDWFSGQHKRLNDVFYKLDALFQHVIDDHLNPGRSKEHEDIIDSMLDVIH--KQGEDSS 286 Query: 1010 ENFIVDNCK----SIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGRP--LD 1171 +D+ K +I+ AG ++ A+T W + L +P+ +V+ ++ E G + Sbjct: 287 LELTIDHIKGFLANIFLAGIDTGAITMIWAVTELVKNPKLIKKVQGDIREQLGSNKERIT 346 Query: 1172 SQSLQKMKNLTMVIQETLRLYPAGAFV-SRMALQELKLGGVHIPKGVNIYIPVSTMHLDP 1348 + ++K+ L MVI+ET RL+PA + R + +K+ G IP I + VS + DP Sbjct: 347 EEDIEKVPYLKMVIKETFRLHPAAPLILPRETMAHIKVQGYDIPPKRRILVNVSAIGRDP 406 Query: 1349 KLWGPDAKEFNPARFSDA----RPQLHSYLPFGAGARTCLG--QGFATAE 1480 KLW + KEF+P RF D+ R Q + LPFG+G R C G G A E Sbjct: 407 KLW-TNPKEFDPERFMDSFVDYRGQHYELLPFGSGRRICPGMPMGIAAVE 455
>Q949P1:ABAH1_ARATH Abscisic acid 8'-hydroxylase 1 - Arabidopsis thaliana (Mouse-ear| cress) Length = 467 Score = 97.4 bits (241), Expect = 2e-19 Identities = 93/382 (24%), Positives = 171/382 (44%), Gaps = 5/382 (1%) Frame = +2 Query: 350 FYEKWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRGI 529 F++ +K +G VF + + +S P+ + + L L K ++ + L + I Sbjct: 60 FFQSKQKRYGSVFKTHVLGCPCVMISSPEAAKFV-LVTKSHLFKPTFPASKERMLGKQAI 118 Query: 530 LKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDD 709 G+ A RK++ F + ++ MV + AQ L WE GT+ I + Sbjct: 119 FFHQGDYHAKLRKLVLRAFMPESIRNMVPDIESIAQDSLRSWE-------GTM-INTYQE 170 Query: 710 IRAYSADVISRTCFGSSYVKGKKIFLKLRE-LQKAVSKPNVLAEMTGLRFFPTKKNRQAW 886 ++ Y+ +V + FG V ++ + L+K + V + G F + K R Sbjct: 171 MKTYTFNVALLSIFGKDEVLYREDLKRCYYILEKGYNSMPV--NLPGTLFHKSMKAR--- 225 Query: 887 GLHKQVHRLILEIVKESGEDKNLLRAILHSASSSKVGLGEAENFIVDNCKSIYFAGYEST 1066 K++ +++ I+ E ++ + +L S K L + + I DN + FA ++T Sbjct: 226 ---KELSQILARILSERRQNGSSHNDLLGSFMGDKEELTDEQ--IADNIIGVIFAARDTT 280 Query: 1067 AVTAAWCLMLLGLHPEWQDRVRQEVLEVCG----GRPLDSQSLQKMKNLTMVIQETLRLY 1234 A +W L L +P + V +E + + G L +KM + VIQETLR+ Sbjct: 281 ASVMSWILKYLAENPNVLEAVTEEQMAIRKDKEEGESLTWGDTKKMPLTSRVIQETLRVA 340 Query: 1235 PAGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARFSDARPQL 1414 +F R A+++++ G IPKG + +H ++ K F+P+RF + P+ Sbjct: 341 SILSFTFREAVEDVEYEGYLIPKGWKVLPLFRNIHHSADIFSNPGK-FDPSRF-EVAPKP 398 Query: 1415 HSYLPFGAGARTCLGQGFATAE 1480 ++++PFG G +C G A E Sbjct: 399 NTFMPFGNGTHSCPGNELAKLE 420
>Q964Q7:CP6D3_MUSDO Cytochrome P450 6d3 - Musca domestica (House fly)| Length = 520 Score = 97.1 bits (240), Expect = 2e-19 Identities = 110/488 (22%), Positives = 198/488 (40%), Gaps = 48/488 (9%) Frame = +2 Query: 143 LALYLYYTVWVVPQRLLAGFRRQGIGGPRPSFPYGNMADXXXXXXXXXXXXXXXXXXXIV 322 L + L +++ +R ++R G+ P+G++A + Sbjct: 5 LLITLLSAIFIFAKRHYTQWQRLGLVSDEAVIPFGSLAK-------------------VF 45 Query: 323 HDYRPAVLPFYEKWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLC---VSLDLG----K 481 RP L Y+ + K V ++L ++RD L ++ D + Sbjct: 46 RKERPFGLVMYDLYEKFQEQVVG------IYLFFKPALLIRDAELARQILTSDFNSFHDR 99 Query: 482 SSYLKATHEPLFGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEA 661 Y+ ++P+ + G++W R + P F K+KGM + + D LLE Sbjct: 100 GIYVDEKNDPM-SANLFALEGQSWRTLRMKLTPSFSSGKLKGMFETVDDVGNKLLEYLNN 158 Query: 662 RVDKSGGTVDIKIDDDIRAYSADVISRTCFG---SSYVKGKKIFLKLRELQKAVSKPNVL 832 ++ K G T + I + Y+ D+I FG S+ F L + + L Sbjct: 159 QL-KDGQTHVLDIKSILTTYAIDIIGSVIFGLEIDSFTNPDNEFRVLSDRSFDNESRSFL 217 Query: 833 AEMTGLRFF---PTKKNRQAWGLHKQVHRLILEIVKESGE--------DKNLLRAILHSA 979 +++ L F P K G + V + +IVK + E K+LL ++ Sbjct: 218 SKLQNLTNFVCPPIAKLLTRLGTKEPVVYRLRDIVKRTIEFREENNVVRKDLLHLLIQLR 277 Query: 980 SSSKVG-----------------LGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLH 1108 ++ K+ + + I N Y AG E+TA + ++ + L ++ Sbjct: 278 NTGKISDDNDNLWNKVESTATNLKAMSIDMIASNSFLFYIAGSETTASSTSFTIYELAMN 337 Query: 1109 PEWQDRVRQEV---LEVCGGRP---LDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQ 1270 PE + + EV L+ G +P + +++Q MK L + ++ET R YP F++R Q Sbjct: 338 PEALKKAQNEVDECLKKHGIKPDGRITYEAIQDMKYLDLCVKETTRKYPGLPFLNRQCTQ 397 Query: 1271 ELKL--GGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARFSDARPQLH--SYLPFGA 1438 + K+ I K N+ I + +H D K + P+ + P RF+D +Y+PFG Sbjct: 398 DFKVPNSKFTIKKDTNVIISLLGLHRDAKYF-PEPLAYKPERFADETKDYDAAAYMPFGE 456 Query: 1439 GARTCLGQ 1462 G R C+ Q Sbjct: 457 GPRHCIAQ 464
>O65786:C71B4_ARATH Cytochrome P450 71B4 - Arabidopsis thaliana (Mouse-ear cress)| Length = 504 Score = 97.1 bits (240), Expect = 2e-19 Identities = 97/404 (24%), Positives = 183/404 (45%), Gaps = 34/404 (8%) Frame = +2 Query: 368 KEHGPVFTYSMGNVVFLHVSRPDVVRDINL-----CVSLDLGKSSYLKATHEPLFGRGIL 532 K+HGPV +G + +S + + C S + +S + + + G G+ Sbjct: 61 KKHGPVMHLRLGFAPMVVISSSEAAEEALKTHDLECCSRPITMASRVFSRNGKDIGFGVY 120 Query: 533 KSNGEAWAHQRKIIAPEFF-LDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDD 709 G+ W RK+ EFF + KV+ + + +++ + K + + Sbjct: 121 ---GDEWRELRKLSVREFFSVKKVQSFKYIREEENDLMIKKLKELASKQS---PVDLSKI 174 Query: 710 IRAYSADVISRTCFGSSYVKGKKIF------LKLRELQKAVSKPNVLAEMTGLRFF---P 862 + +A +I RT FG S+ K + L L + + GL++F Sbjct: 175 LFGLTASIIFRTAFGQSFFDNKHVDQESIKELMFESLSNMTFRFSDFFPTAGLKWFIGFV 234 Query: 863 TKKNRQAWGLHKQVHRLILEIV-----KESGEDK-NLLRAILHSASSSKVGLGEAENFIV 1024 + ++++ + + +V IV K++ +D+ +++ AIL + + + V Sbjct: 235 SGQHKRLYNVFNRVDTFFNHIVDDHHSKKATQDRPDMVDAILDMIDNEQQYA--SFKLTV 292 Query: 1025 DNCK----SIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCG----GRPLDSQS 1180 D+ K +IY AG +++A+T W + L +P + + E+ G GR ++ + Sbjct: 293 DHLKGVLSNIYHAGIDTSAITLIWAMAELVRNPRVMKKAQDEIRTCIGIKQEGRIME-ED 351 Query: 1181 LQKMKNLTMVIQETLRLYPAG-AFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLW 1357 L K++ L +V++ETLRL+PA + R + ++K+ G IP+ + + ++ DP+ W Sbjct: 352 LDKLQYLKLVVKETLRLHPAAPLLLPRETMADIKIQGYDIPQKRALLVNAWSIGRDPESW 411 Query: 1358 GPDAKEFNPARFSDARPQL--HSY--LPFGAGARTCLGQGFATA 1477 + +EFNP RF D HS+ LPFG+G R C G A A Sbjct: 412 -KNPEEFNPERFIDCPVDYKGHSFELLPFGSGRRICPGIAMAIA 454
>P30437:CP17A_ONCMY Cytochrome P450 17A1 - Oncorhynchus mykiss (Rainbow trout) (Salmo| gairdneri) Length = 514 Score = 96.7 bits (239), Expect = 3e-19 Identities = 87/344 (25%), Positives = 151/344 (43%), Gaps = 26/344 (7%) Frame = +2 Query: 671 KSGGTVDIKIDDDIRAYSADVISRTCFGSSYVKGKKIFLKLRELQKA----VSKPNVLAE 838 + G+ + + ++ +V+ CF SSY +G F + + + V+K +++ Sbjct: 164 RESGSASLDLSPELTRAVTNVVCSLCFSSSYCRGDPEFEAMLQFSQGIVDTVAKDSLVDI 223 Query: 839 MTGLRFFPTKKNRQAWGLHKQVHRLILEIVKESGED------KNLLRAILHSASSSKVG- 997 L+ FP R +L+ + +E D ++LL A+L + S++ Sbjct: 224 FPWLQVFPNADLRLLKQCVSIRDKLLQKKYEEHKSDYSDHEQRDLLDALLRAKRSAENNN 283 Query: 998 --------LGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVC 1153 +G +E+ ++ I+ AG E+T+ W + L HP+ Q R+++E+ V Sbjct: 284 TAEITMETVGLSEDHLLMTVGDIFGAGVETTSTVLKWAIAYLIHHPQVQQRIQEELDSVV 343 Query: 1154 GG-RPLDSQSLQKMKNLTMVIQETLRLYP-AGAFVSRMALQELKLGGVHIPKGVNIYIPV 1327 GG R + L I+E LR+ P A + +A + +G + KG I I + Sbjct: 344 GGDRTPQLSDRGSLPYLEATIREVLRIRPVAPLLIPHVAQTDTSIGKFTVRKGARIIINL 403 Query: 1328 STMHLDPKLWGPDAKEFNPARFSDARP-----QLHSYLPFGAGARTCLGQGFATAEXXXX 1492 ++H D K W + + F+P RF + SYLPFGAG R CLG+ A E Sbjct: 404 WSLHHDEKEW-KNPEMFDPGRFLNEEGTGLCIPSPSYLPFGAGVRVCLGEALAKMEIFLF 462 Query: 1493 XXXXXXXFALRLSPLYQHSPALKLIVEPEFGVDITLTKVQTAST 1624 + +SP Q P+L E +FGV + K + +T Sbjct: 463 LSWILQRLTMTVSP-GQPLPSL----EGKFGVVLQPVKYKVNAT 501
>P37121:C76A1_SOLME Cytochrome P450 76A1 - Solanum melongena (Eggplant) (Aubergine)| Length = 467 Score = 96.7 bits (239), Expect = 3e-19 Identities = 87/345 (25%), Positives = 152/345 (44%), Gaps = 26/345 (7%) Frame = +2 Query: 503 HEPLFGRGILKSNGEAWAHQRKIIAPEFFLDK-VKGMVDLMVDSAQTLLEPWEARVDKSG 679 H G L G W R+I E F+ K + ++ +S +L E + SG Sbjct: 69 HNYYKGSMALAPYGNYWRFSRRICTVEMFVHKRINETTNIRQESVDKMLRLDEEKASSSG 128 Query: 680 GTVD-IKIDDDIRAYSADVISRTCFGSSYV------KGKKIFLKLRELQKAVSKPNVLAE 838 G + I++ + S +++ F V +G + F + + + PN+ Sbjct: 129 GGGEGIEVTRYMFLASFNMVGNMIFSKDLVTDPESKQGSEFFNAMIGIMEWAGVPNISDI 188 Query: 839 MTGLRFFPT----KKNRQAWGLHKQVHRLILEI---VKESGED----KNLLRAILHSASS 985 L+ F KK + G K++ + +E ++ GE K+LL ++ S Sbjct: 189 FPCLKMFDVQGLRKKMERDMGKGKEITKKFIEERIEERKKGEKNRSIKDLLDVLIDFEGS 248 Query: 986 SKVGLGE-AENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCG-G 1159 K + +E+ I ++ AG E+T+ + W L L HP+ +V+ E+L+V G Sbjct: 249 GKDEPDKLSEDEITVIILEMFLAGTETTSSSVEWALTELLRHPQAMAKVKLEILQVIGPN 308 Query: 1160 RPLDSQSLQKMKNLTMVIQETLRLY-PAGAFVSRMALQELKLGGVHIPKGVNIYIPVSTM 1336 + + + + + V++E LRL+ P + R A+Q+ K G IPKG + + + Sbjct: 309 KKFEECDIDSLPYMQAVLKEQLRLHPPLPLLIPRKAIQDTKFMGYDIPKGTQVLVNAWAI 368 Query: 1337 HLDPKLWGPDAKEFNPARF----SDARPQLHSYLPFGAGARTCLG 1459 DP+ W + EF P RF D + Q + +PFGAG R C+G Sbjct: 369 GRDPEYW-DNPFEFKPERFLESKVDVKGQNYELIPFGAGRRMCVG 412
>Q9V675:CP6G2_DROME Probable cytochrome P450 6g2 - Drosophila melanogaster (Fruit fly)| Length = 519 Score = 96.3 bits (238), Expect = 4e-19 Identities = 109/482 (22%), Positives = 206/482 (42%), Gaps = 35/482 (7%) Frame = +2 Query: 128 VGACSLALYLYYTVWVVPQRLLAGFRRQGIGGPRPSFPYGNMADXXXXXXXXXXXXXXXX 307 +G LAL +Y+ W RR G+ RP + GN+ Sbjct: 13 IGIAFLALQQHYSYW----------RRMGVREIRPKWIVGNLMGLLNMRMSPAEF----- 57 Query: 308 XXXIVHDYRPAVLPFYEKWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSS 487 + Y E+ P + + L + P++VR N+ V G S+ Sbjct: 58 -----------ISQLYNHPDAENEPFVGIHVFHKPALLLRDPEMVR--NILVKDFAGFSN 104 Query: 488 YLKATH---EPLFGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWE 658 ++ +PL + I AW R ++P F +++K M L+ + +L Sbjct: 105 RYSSSDPKGDPLGSQNIFFLKNPAWKEVRLKLSPFFTGNRLKQMFPLIEEVGASLDAHLR 164 Query: 659 ARV--DKSGGTVDIKIDDDIRAYSADVISRTCFGSSYVKGKKIFLKLRELQKAVSKPNVL 832 + ++ D++ + Y+ DVI+ +G S + R ++V + N+L Sbjct: 165 QQPLHNERMRCFDLEAKELCALYTTDVIATVAYGVSANSFTDPKCEFRRHGRSVFEFNLL 224 Query: 833 --AEMTGLRFFP---------TKKNRQAWGLHKQVHRLILEIVKESGEDKNLLRAILHSA 979 AE T + F P L K ++ ++ E K + +L+ ++ Sbjct: 225 RAAEFTLVFFLPHLVPFVRFKVVPAEATRFLRKTINYVMSEREKSGQKRNDLIDILIEFR 284 Query: 980 SSSKVGL--GEAENFIVDN----CKSIYF--AGYESTAVTAAWCLMLLGLHPEWQDRVRQ 1135 S+++ G + F+ + +++ F AG+ES++ T A+ + L + Q R+R+ Sbjct: 285 RSTQLAKASGIKDQFVFEGDILVAQAVLFFTAGFESSSSTMAFAMYELAKDTDVQQRLRE 344 Query: 1136 EVLE--VCGGRPLDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMAL--QELKLGGVH--- 1294 E+ + V G + + ++ ++ + M++ E LR+YP F+ R ++ L H Sbjct: 345 EIKDALVESGGQVTLKMIESLEFMQMILLEVLRMYPPLPFLDRECTSGRDYSLAPFHKKF 404 Query: 1295 -IPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARFSDARPQLH---SYLPFGAGARTCLGQ 1462 +PKG+ +YIP +H+DP+ + P ++F P RFS +LH +Y+PFG G C+G+ Sbjct: 405 VVPKGMPVYIPCYALHMDPQYF-PQPRKFLPERFSPENRKLHTPYTYMPFGLGPHGCIGE 463 Query: 1463 GF 1468 F Sbjct: 464 RF 465
>Q9LTL2:C71BP_ARATH Cytochrome P450 71B25 - Arabidopsis thaliana (Mouse-ear cress)| Length = 501 Score = 96.3 bits (238), Expect = 4e-19 Identities = 95/406 (23%), Positives = 177/406 (43%), Gaps = 36/406 (8%) Frame = +2 Query: 368 KEHGPVFTYSMGNVVFLHVSRPDVVR------DINLCVSLDLGKSSYLKATHEPLFGRGI 529 K+HGPV +G V + +S + DI C + + ++ + Sbjct: 61 KKHGPVMHLQLGFVPLVLISSSEAAEEALKTHDIECCTRPNTNAARVFSRNNKNIG---- 116 Query: 530 LKSNGEAWAHQRKIIAPEFF-LDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDD 706 L + + W RK+ E+F + KV+ + + +++ K + + Sbjct: 117 LGAYSDEWRELRKVAVREYFSVKKVQSFRYVREEENHLMVKKLRDLALKQS---PVDLSK 173 Query: 707 DIRAYSADVISRTCFGSSYVKGK-----KIFLKLRELQKAVS-KPNVLAEMTGLRFFPTK 868 + +A + R FG S+ K KI + E QK+++ K + L + GL +F Sbjct: 174 TLFCLAASTVFRPVFGQSFSDNKHFSEEKIEELVFEAQKSLTFKFSDLFPIPGLGWFIGF 233 Query: 869 KNRQAWGLHK---QVHRLILEIVKESGEDKN---------LLRAILHSASSSKVGLGEAE 1012 + Q GLHK +V + ++ + + L ++H+ K + Sbjct: 234 VSGQHKGLHKVFIEVDNFLNHMIDDHQKQNQPQDRSDIVGSLLDMIHNQEQDK-----SF 288 Query: 1013 NFIVDNCKSI----YFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGRP--LDS 1174 +D+ K I + AG +++A+T W + L +P +V+ E+ G + ++ Sbjct: 289 KLTIDHLKGITQDIFLAGIDTSAITMIWAMAELVNNPRVMKKVQDEIRSCIGIKKERIEE 348 Query: 1175 QSLQKMKNLTMVIQETLRLYPAG-AFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPK 1351 + + K++ L +VI+ETLRL+PA + R + ++K+ G IP+ + + ++ DPK Sbjct: 349 EDVGKLQYLKLVIKETLRLHPAAPLLLPRETMADIKIQGYDIPRKTLLLVSAWSLGRDPK 408 Query: 1352 LWGPDAKEFNPARFSDA----RPQLHSYLPFGAGARTCLGQGFATA 1477 W + +EFNP RF D + +LPFG+G R C G A A Sbjct: 409 YW-KNPEEFNPERFIDCPVDYKGHSFEFLPFGSGRRFCPGMASAIA 453
>O69653:CP137_MYCTU Putative cytochrome P450 137 - Mycobacterium tuberculosis| Length = 476 Score = 95.9 bits (237), Expect = 5e-19 Identities = 81/319 (25%), Positives = 143/319 (44%), Gaps = 12/319 (3%) Frame = +2 Query: 560 QRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAYSADVIS 739 +RK++ P + V ++ +S + + W VD+ + + R+ DVI Sbjct: 140 RRKLLTPPLHGAALDRYVPIIENSTRAAMHTWP--VDRPFAMLTVA-----RSLMLDVIV 192 Query: 740 RTCFG----SSYVKGKKIFLKLREL--QKAVSKPNVLAEMTGLRFFPTKKNRQAWGLHKQ 901 + FG + + F +L L + ++ L + LR +P + + Sbjct: 193 KVIFGVDDPEEVRRLGRPFERLLNLGVSEQLTVRYALRRLGALRVWPARARANT-----E 247 Query: 902 VHRLILEIVKES------GEDKNLLRAILHSASSSKVGLGEAENFIVDNCKSIYFAGYES 1063 + +++ ++ + GE ++L ++ + S L ++E I D+ ++ AG+E+ Sbjct: 248 IDDVVMALIAQRRADPRLGERHDVLSLLVSARGESGEQLSDSE--IRDDLITLVLAGHET 305 Query: 1064 TAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGRPLDSQSLQKMKNLTMVIQETLRLYPAG 1243 TA T AW LL HP+ RVR E V GG T VI ETLR+ P Sbjct: 306 TATTLAWAFDLLLHHPDALRRVRAEA--VGGGEAFT----------TAVINETLRVRPPA 353 Query: 1244 AFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARFSDARPQLHSY 1423 +R+A Q L +GG + G I + + ++ +++ EF P RF RPQ +++ Sbjct: 354 PLTARVAAQPLTIGGYRVEAGTRIVVHIIAINRSAEVY-EHPHEFRPERFLGTRPQTYAW 412 Query: 1424 LPFGAGARTCLGQGFATAE 1480 +PFG G + CLG F+ E Sbjct: 413 VPFGGGVKRCLGANFSMRE 431
>P93530:C71D6_SOLCH Cytochrome P450 71D6 - Solanum chacoense (Chaco potato)| Length = 501 Score = 95.9 bits (237), Expect = 5e-19 Identities = 91/395 (23%), Positives = 170/395 (43%), Gaps = 25/395 (6%) Frame = +2 Query: 368 KEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRGILKSN-- 541 K++GP+ +G V + V+ PD+ +++ + L A + R + + Sbjct: 61 KKYGPLMHLQLGEVSAVVVTSPDMAKEVLKTHDIAFASRPKLLAMDIICYDRCDIAFSPY 120 Query: 542 GEAWAHQRKIIAPEFFLDK-VKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRA 718 GE W RKI E K V+ + D L++ ++ SG V+ K + + Sbjct: 121 GEYWKQMRKICVTEVLSAKSVRSFSSIRCDEVVRLIDSIQSS-SSSGELVNFK--ERVIW 177 Query: 719 YSADVISRTCFGSSYVKGKKIFLKL-RELQKAVSKPNVLAEMTGLRFFPT--KKNRQAWG 889 +++ + R+ FG K + +F+KL RE+ + +V +F + R+ Sbjct: 178 FTSSMTCRSAFGQ-LPKEQDMFIKLIREVIRLAEGFDVADIFPSYKFLHVFGRAKRKLLN 236 Query: 890 LHKQVHRLILEIVKESGED-------------KNLLRAILHSASSSKVGLGEAENFIVDN 1030 +H++V ++ +++ E ++ +NL+ +L + + + I Sbjct: 237 VHRKVDAIVEDVINEHKKNFATRKNDDHALGGENLIDVLLKLMNDKSLQFPINNDNIKAI 296 Query: 1031 CKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGR-PLDSQSLQKMKNLTM 1207 ++ AG E+++ T W ++ + +P + + EV E + D ++ +K L + Sbjct: 297 IIDMFAAGTETSSTTTVWAMVEMLKNPRVLAKAQAEVREAFRNKVTFDENDVEDLKYLKL 356 Query: 1208 VIQETLRLY-PAGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNP 1384 VI+ET+RL+ P V R +E ++ G IP + + V + DPK W D + F P Sbjct: 357 VIKETMRLHAPIPLLVPRECRKETEINGYTIPVKTKVMVNVWALGRDPKYWD-DVECFKP 415 Query: 1385 ARFSDARPQL----HSYLPFGAGARTCLGQGFATA 1477 RF YLPFG G R C G F A Sbjct: 416 ERFEQCSIDFIGNNFEYLPFGGGRRICPGTSFGLA 450
>Q27606:CP4E2_DROME Cytochrome P450 4e2 - Drosophila melanogaster (Fruit fly)| Length = 526 Score = 95.5 bits (236), Expect = 6e-19 Identities = 84/363 (23%), Positives = 149/363 (41%), Gaps = 29/363 (7%) Frame = +2 Query: 479 KSSYLKATHEPLFGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWE 658 KS + TH P G G+L S G W RK+I P F + ++ ++M +++ ++ + Sbjct: 101 KSDIYQLTH-PWLGLGLLTSTGSKWHKHRKMITPAFHFNILQDFHEVMNENSTKFIKHLK 159 Query: 659 ARVDKSGGTVDIKIDDDIRAYSADVISRTCFGSSYVKGKKIFLKLRELQKAVSKPNVLAE 838 + G + + DVI T G S ++ R + ++ Sbjct: 160 T---VAAGDNIFDFQEQAHYLTLDVICDTAMGVSINA-----MENRSSSIVQAFKDMCYN 211 Query: 839 MTGLRFFPTKKNRQAWGLHKQVHRLILEIVKESGEDKNLLRAILHSASSSKVGLGEAENF 1018 + F P K+N + L + ++ + + S V + F Sbjct: 212 INMRAFHPLKRNELLYRLAPDYPAYSRTLKTLQDFTNEIIAKRIEAHKSGAVSTNAGDEF 271 Query: 1019 I--------------VD----NCKSIY-------FAGYESTAVTAAWCLMLLGLHPEWQD 1123 +D N K +Y F G+++T ++ + LL H + Q Sbjct: 272 TRKKMAFLDTLLSSTIDGRPLNSKELYEEVSTFMFEGHDTTTSGVSFAVYLLSRHQDEQR 331 Query: 1124 RVRQEVLEVCG----GRPLDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKLGGV 1291 ++ +E EV G GR Q + +MK L + I+E R+YP+ F+ R ++ + G Sbjct: 332 KLFKEQREVMGNSELGRDATFQEISQMKYLDLFIKEAQRVYPSVPFIGRFTEKDYVIDGD 391 Query: 1292 HIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARFSDARPQLHSYLPFGAGARTCLGQGFA 1471 +PKG + + + + + K++ D +F P RF +P Y+PF AG R C+GQ FA Sbjct: 392 LVPKGTTLNLGLVMLGYNEKVF-KDPHKFRPERFELEKPGPFEYVPFSAGPRNCIGQKFA 450 Query: 1472 TAE 1480 E Sbjct: 451 LLE 453
>Q9SCN2:C71BU_ARATH Cytochrome P450 71B31 - Arabidopsis thaliana (Mouse-ear cress)| Length = 498 Score = 95.5 bits (236), Expect = 6e-19 Identities = 95/393 (24%), Positives = 170/393 (43%), Gaps = 30/393 (7%) Frame = +2 Query: 371 EHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRGI----LKS 538 EHGPV G V S + +++ + DL + K LF G Sbjct: 58 EHGPVMLVRWGVVPMAVFSSNEAAKEV--LKTHDLETCNRPKLVANGLFTHGYKDIGFTQ 115 Query: 539 NGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRA 718 GE W +K + E F K + + LL + ++ VD++ + + Sbjct: 116 YGEEWREMKKFVGLELFSPKKHKSFRYIREEEGDLLVKKISNYAQTQTLVDLR--KSLFS 173 Query: 719 YSADVISRTCFGSSYVKGKKIFL-KLRELQKAVSKPNVLAEMTGLRFFPTKKN---RQAW 886 Y+A +I R FG ++ + I + KL EL + ++ NV + + FFP + Sbjct: 174 YTASIIFREAFGQNFRECDYINMDKLEELVQE-TETNVCS-LAFTDFFPRGLGWLVDRIS 231 Query: 887 GLHKQVHRLILEIV-------------KESGEDKNLLRAILHSASSSKV--GLGEAENFI 1021 G H +++ ++ K+ + +L+ A+L + + L + + Sbjct: 232 GQHSRMNIAFSKLTTFFEDVIDELLKTKQLDDHSDLVTAMLDVINRPRKFGSLKITYDHL 291 Query: 1022 VDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGRP--LDSQSLQKMK 1195 + + AG + VT W + L HP ++++E+ G + + L+K++ Sbjct: 292 IAMMSDVVLAGVNAGTVTMIWTMTELTRHPRVMKKLQEEIRATLGPNKERITEEDLEKVE 351 Query: 1196 NLTMVIQETLRLYP-AGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWGPDAK 1372 L +VI+E+ RL+P A + R + ++++ G HIPK ++ I + DPK W + + Sbjct: 352 YLNLVIKESFRLHPPAPLLLPRETMSDIEIQGYHIPKNAHVKINTYAIGRDPKRW-TNPE 410 Query: 1373 EFNPARFSDA----RPQLHSYLPFGAGARTCLG 1459 EFNP RF + + Q + LPFGAG R C G Sbjct: 411 EFNPERFLNTSINYKGQHYELLPFGAGRRNCPG 443
>O65784:C71B5_ARATH Cytochrome P450 71B5 - Arabidopsis thaliana (Mouse-ear cress)| Length = 498 Score = 95.5 bits (236), Expect = 6e-19 Identities = 103/405 (25%), Positives = 170/405 (41%), Gaps = 38/405 (9%) Frame = +2 Query: 359 KWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRGI--- 529 K +E+GPV G V + VS + ++ + DL S K LF Sbjct: 54 KISQEYGPVMLLHFGVVPVIIVSSKEGAEEV--LKTHDLETCSRPKTVGSGLFTYNFKDI 111 Query: 530 -LKSNGEAWAHQRKIIAPEFFLDK-VKGMVDLMVDSAQTLLEPWEARVDKSG---GTVDI 694 GE W RKI E F K +K + D +Q L+ +V KS T + Sbjct: 112 GFAPYGENWREMRKIAVSELFSQKKLKSFRYIREDESQLLVR----KVSKSALETPTSSV 167 Query: 695 KIDDDIRAYSADVISRTCFGSSYVKGKKIFLKLRELQKAVSKPNV-LAEMTGLRFFPTKK 871 + I ++A +I R FG ++ F+ + +++ V + L + F P Sbjct: 168 NLRKVIFTFAASIICRLSFGQNFCD----FVDMETVEELVLESETNLGSLAFADFLPA-- 221 Query: 872 NRQAW------GLHKQVHR----------LILEIVKESG--EDKNLLRAILHSASSSKVG 997 W G H V + L+++ +SG ED + + +++ + Sbjct: 222 ---GWIIDRISGQHSTVMKAFSKLTNFFELVIDDHLKSGKIEDHSDIISVMLDMINKPTE 278 Query: 998 LGE---AENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGRP- 1165 +G ++ + ++ AG + ++T W + L HP ++++E+ G Sbjct: 279 VGSYKVTDDHLKGLMSDVFLAGVNAGSITMIWTMTELSRHPRVMRKLQEEIRAALGPNKE 338 Query: 1166 -LDSQSLQKMKNLTMVIQETLRLYP-AGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMH 1339 + + L+K++ L MVI+E RL+P A + R+ + ++ + G IPK I I T+ Sbjct: 339 KITEEDLEKVEYLKMVIEEAFRLHPPAPLLLPRLTMSDINIQGYSIPKNTMIQINTYTIG 398 Query: 1340 LDPKLW-GPDAKEFNPARFSD----ARPQLHSYLPFGAGARTCLG 1459 DPK W PD EF P RF D + Q LPFGAG R C G Sbjct: 399 RDPKNWTKPD--EFIPERFVDNPIEYKGQHFELLPFGAGRRVCPG 441
>Q12573:CP52W_CANAP Cytochrome P450 52E2 - Candida apicola (Yeast)| Length = 519 Score = 95.1 bits (235), Expect = 8e-19 Identities = 94/362 (25%), Positives = 149/362 (41%), Gaps = 39/362 (10%) Frame = +2 Query: 512 LFGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVD 691 L G GI +G+ W + R ++ P+F ++V + +S +T + K G VD Sbjct: 125 LLGNGIFTLSGDGWKNSRALLRPQFSREQVSHL-----ESMRTHINMMINNHFKGGQVVD 179 Query: 692 IKIDDDIRAYSADVISRTCFGSSY-----------VKGKKIFLKLRELQKAVSKPNVLAE 838 ++ + D + FG S + G K + + +A + L Sbjct: 180 AQVL--YHNLTIDTATEFLFGESTNTLDPALAQQGLPGPKGLVTGEQFAEAFTSALELLS 237 Query: 839 ---MTGLRFFPTKKNRQAWGLHKQVHRLI-------LEIVKESGEDKN---LLRAILHSA 979 M G +F + W K H I L E G+D + +R + Sbjct: 238 VRVMAGAAWFLVWTPK-FWRSCKVCHNFIDYFVYKALATPMEKGQDADRYVFIRELTKET 296 Query: 980 SSSKVGLGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGG 1159 S +V I D +I AG ++TA ++ LG +PE D +R+ V+ G Sbjct: 297 SDPRV--------IRDQALNILLAGRDTTAALLSFTTYYLGAYPEVYDELREAVIADFGS 348 Query: 1160 ---RPLDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKL---GG------VHIPK 1303 P + L++ K L VI+E LRL+P R A+ + GG + +PK Sbjct: 349 ADAEPPTFEQLKQCKVLQNVIREVLRLHPNVPLNFREAIADTTFPTGGGPNGDQPIFVPK 408 Query: 1304 GVNIYIPVSTMHLDPKLWGPDAKEFNPARFSDARPQLHS---YLPFGAGARTCLGQGFAT 1474 G ++ M + +WGPD+ F P R+++ R L S Y+PF G R CLGQ FA Sbjct: 409 GQKVFYATYVMQRNAGIWGPDSTSFRPDRWNEPREALASGWDYIPFNGGPRICLGQQFAL 468 Query: 1475 AE 1480 E Sbjct: 469 TE 470
>P63719:CP139_MYCTU Putative cytochrome P450 139 - Mycobacterium tuberculosis| Length = 430 Score = 95.1 bits (235), Expect = 8e-19 Identities = 84/328 (25%), Positives = 141/328 (42%), Gaps = 10/328 (3%) Frame = +2 Query: 527 ILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDD 706 ++ S+G +R ++AP V+ V MV + T+++ W+ G +DI Sbjct: 66 LIVSDGADHRRRRSVVAPGLRHHHVQRYVATMVSNIDTVIDGWQP-----GQRLDIY--Q 118 Query: 707 DIRAYSADVISRTCFGSSY-VKGKKIFLKLRELQKAVSKPNVLAEMTGLRFFPTKKNRQA 883 ++R+ + + FG V + +L+ L +P + + P R+A Sbjct: 119 ELRSAVRRSTAESLFGQRLAVHSDFLGEQLQPLLDLTRRPPQVMRLQQRVNSPGW--RRA 176 Query: 884 WGLHKQVHRLILEIVKESGE----DKNLLRAILHSASSSKVGLGEAENFIVDNCKSIYFA 1051 K++ LI + ++ D ++L ++ S L ++N I D+ S+ A Sbjct: 177 MAARKRIDDLIDAQIADARTAPRPDDHMLTTLISGCSEEGTTL--SDNEIRDSIVSLITA 234 Query: 1052 GYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGRPLDSQSLQKMKNLTMVIQETLRL 1231 GYE+T+ AW + L P + EV V GGR + L + L V+ ETLRL Sbjct: 235 GYETTSGALAWAIYALLTVPGTWESAASEVARVLGGRVPAADDLSALTYLNGVVHETLRL 294 Query: 1232 YPAGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARFSD---- 1399 Y G +R L++L G I G + H P++W P+ EF P R+ Sbjct: 295 YSPGVISARRVLRDLWFDGHRIRAGRLLIFSAYVTHRLPEIW-PEPTEFRPLRWDPNAAD 353 Query: 1400 -ARPQLHSYLPFGAGARTCLGQGFATAE 1480 +P H ++PF G C+G AT E Sbjct: 354 YRKPAPHEFIPFSGGLHRCIGAVMATTE 381
>P63720:CP139_MYCBO Putative cytochrome P450 139 - Mycobacterium bovis| Length = 430 Score = 95.1 bits (235), Expect = 8e-19 Identities = 84/328 (25%), Positives = 141/328 (42%), Gaps = 10/328 (3%) Frame = +2 Query: 527 ILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDD 706 ++ S+G +R ++AP V+ V MV + T+++ W+ G +DI Sbjct: 66 LIVSDGADHRRRRSVVAPGLRHHHVQRYVATMVSNIDTVIDGWQP-----GQRLDIY--Q 118 Query: 707 DIRAYSADVISRTCFGSSY-VKGKKIFLKLRELQKAVSKPNVLAEMTGLRFFPTKKNRQA 883 ++R+ + + FG V + +L+ L +P + + P R+A Sbjct: 119 ELRSAVRRSTAESLFGQRLAVHSDFLGEQLQPLLDLTRRPPQVMRLQQRVNSPGW--RRA 176 Query: 884 WGLHKQVHRLILEIVKESGE----DKNLLRAILHSASSSKVGLGEAENFIVDNCKSIYFA 1051 K++ LI + ++ D ++L ++ S L ++N I D+ S+ A Sbjct: 177 MAARKRIDDLIDAQIADARTAPRPDDHMLTTLISGCSEEGTTL--SDNEIRDSIVSLITA 234 Query: 1052 GYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGRPLDSQSLQKMKNLTMVIQETLRL 1231 GYE+T+ AW + L P + EV V GGR + L + L V+ ETLRL Sbjct: 235 GYETTSGALAWAIYALLTVPGTWESAASEVARVLGGRVPAADDLSALTYLNGVVHETLRL 294 Query: 1232 YPAGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARFSD---- 1399 Y G +R L++L G I G + H P++W P+ EF P R+ Sbjct: 295 YSPGVISARRVLRDLWFDGHRIRAGRLLIFSAYVTHRLPEIW-PEPTEFRPLRWDPNAAD 353 Query: 1400 -ARPQLHSYLPFGAGARTCLGQGFATAE 1480 +P H ++PF G C+G AT E Sbjct: 354 YRKPAPHEFIPFSGGLHRCIGAVMATTE 381
>P58045:C71AE_ARATH Cytochrome P450 71A14 - Arabidopsis thaliana (Mouse-ear cress)| Length = 497 Score = 95.1 bits (235), Expect = 8e-19 Identities = 98/394 (24%), Positives = 168/394 (42%), Gaps = 26/394 (6%) Frame = +2 Query: 374 HGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRG---ILKSNG 544 +GP+ G V L VS DV D+ L + LK E +F G + G Sbjct: 64 YGPLMLLHFGRVPVLVVSSSDVAHDLMKTHDLKVANRPQLKVV-EKIFNGGREMVFSPYG 122 Query: 545 EAWAHQRKIIAPEFF-LDKVKGMVDLMVDSAQTLLEPWEARVDK-SGGTVDIKIDDDIRA 718 E W + + KV+ + + ++E RV+K S + + + + + Sbjct: 123 EYWRQIKSVCIVNLLNKKKVQSFEKVREEEISEMME----RVEKASSDSSPLNLSELLLT 178 Query: 719 YSADVISRTCFGSSYVKGKKIF---LKLRELQKAVSKPNVLAEMTGLRFFPTKK--NRQA 883 ++DV SR G Y K + + +++R++ + V V + L + + + +A Sbjct: 179 LTSDVTSRVSLGRKYSKEESMSDFKIQMRKITELVGGFPVGEYIPCLAWIDKLRGVDEKA 238 Query: 884 WGLHKQVHRLILEIVKE--SGEDKN-------LLRAILHSASSSKVGLGEAENFIVDNCK 1036 + K L+ ++++E DK LL H + ++ + + I+D Sbjct: 239 EEVSKAFGDLMEKVLQEHLDATDKPTLDFVDVLLSLERHERNGVQIRRSDIKFLILD--- 295 Query: 1037 SIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGRPL--DSQSLQKMKNLTMV 1210 ++ AG E+T W + L HPE +++ E+ L + ++ MK L V Sbjct: 296 -MFLAGTETTYALLEWIMTELIRHPECMKKLQDEIRAKATKLILYISEEDVEDMKYLKAV 354 Query: 1211 IQETLRLYPA-GAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPA 1387 ++E LRL+P V R +++KL G I G + I + D WG DA+EF P Sbjct: 355 VKEVLRLHPPLPLLVPRELSEDIKLKGYDIAAGTQVIINAWAIQRDTMTWGIDAEEFRPE 414 Query: 1388 RFSDA----RPQLHSYLPFGAGARTCLGQGFATA 1477 R D+ R ++PFG+G R C G GFA A Sbjct: 415 RHLDSLVDFRGTNFEFIPFGSGRRICPGIGFAMA 448
>Q9V774:C6A21_DROME Probable cytochrome P450 6a21 - Drosophila melanogaster (Fruit fly)| Length = 504 Score = 95.1 bits (235), Expect = 8e-19 Identities = 96/350 (27%), Positives = 157/350 (44%), Gaps = 29/350 (8%) Frame = +2 Query: 506 EPLFGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGT 685 +PL G+ L +G+ W R ++ F K+K M +V A + + V KS Sbjct: 114 DPLSGQLFLL-DGQKWRTMRNKLSSTFTSGKMKYMFPTVVKVANEFTDVFGQNVAKSPV- 171 Query: 686 VDIKIDDDIRAYSADVISRTCFGSSYVKGKKIFLKLRELQKAVSKPNVLAEMTGLRF--- 856 +++ + + ++ DVI FG K + RE+ + L + G+ F Sbjct: 172 --VEVRELLARFTTDVIGTCAFGIECSSLKDPDAEFREMGRRSLTEQRLGPV-GIGFVNS 228 Query: 857 FPTKKNRQAWGLHKQ-VHRLILEIVKES---GEDKNLLR-------------AILHSASS 985 FP R + + + R + IV+E+ E N+ R ++ S S Sbjct: 229 FPNLARRLHMKMTAEPIERFFMRIVRETVAFREQNNIRRNDFMDQLIDLKNKPLMVSQSG 288 Query: 986 SKVGLGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQ---EVLEVCG 1156 V L E I + AG+E+++ T + L L + + Q+RVR+ EV+E C Sbjct: 289 ESVNLTIEE--IAAQAFVFFAAGFETSSTTMGFALYELAQNQDIQNRVRKECQEVIEKCN 346 Query: 1157 GRPLDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKLGG---VHIPKGVNIYIPV 1327 G L+ +S++ + L V+ ETLRLY ++R L++ ++ G I KG+ + IP Sbjct: 347 GE-LNYESMKDLVYLDQVVSETLRLYTVLPVLNRECLEDYEVPGHPKYVIKKGMPVLIPC 405 Query: 1328 STMHLDPKLWGPDAKEFNPARFSDARPQLH---SYLPFGAGARTCLGQGF 1468 MH D KL+ + FNP FS R + +LPFG G R C+G F Sbjct: 406 GAMHRDEKLYA-NPNTFNPDNFSPERVKERDSVEWLPFGDGPRNCIGMRF 454
>O81077:ABAH2_ARATH Abscisic acid 8'-hydroxylase 2 - Arabidopsis thaliana (Mouse-ear| cress) Length = 482 Score = 95.1 bits (235), Expect = 8e-19 Identities = 88/382 (23%), Positives = 166/382 (43%), Gaps = 5/382 (1%) Frame = +2 Query: 350 FYEKWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRGI 529 F+ + ++G +F + + +S P+ R + L L K +Y + + + Sbjct: 73 FFATRQNKYGDIFKTHILGCPCVMISSPEAARMV-LVSKAHLFKPTYPPSKERMIGPEAL 131 Query: 530 LKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDD 709 G + ++++ F ++ V + L W ++ KS T++ Sbjct: 132 FFHQGPYHSTLKRLVQSSFMPSALRPTVSHIELLVLQTLSSWTSQ--KSINTLEY----- 184 Query: 710 IRAYSADVISRTCFGSSYVKGKKIFLKLRELQKAVSKPNVLAEMTGLRFFPTKKNRQAWG 889 ++ Y+ DV + FG +KL + ++ ++ G F + K R Sbjct: 185 MKRYAFDVAIMSAFGDKEEPTTIDVIKLLYQRLERGYNSMPLDLPGTLFHKSMKARIE-- 242 Query: 890 LHKQVHRLILEIVKESGEDKNLLRAILHSASSSKVGLGEAENFIVDNCKSIYFAGYESTA 1069 L +++ ++I + + E+ LL +L + + GL +++ I DN + FA ++TA Sbjct: 243 LSEELRKVIEKRRENGREEGGLLGVLLGAKDQKRNGLSDSQ--IADNIIGVIFAATDTTA 300 Query: 1070 VTAAWCLMLLGLHPEWQDRVRQEVLEVCG-----GRPLDSQSLQKMKNLTMVIQETLRLY 1234 W L L HP V +E + R + + +KM T VIQETLR Sbjct: 301 SVLTWLLKYLHDHPNLLQEVSREQFSIRQKIKKENRRISWEDTRKMPLTTRVIQETLRAA 360 Query: 1235 PAGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARFSDARPQL 1414 +F R A+Q+++ G IPKG + +H + + PD ++F+P+RF + P+ Sbjct: 361 SVLSFTFREAVQDVEYDGYLIPKGWKVLPLFRRIHHSSEFF-PDPEKFDPSRF-EVAPKP 418 Query: 1415 HSYLPFGAGARTCLGQGFATAE 1480 ++Y+PFG G +C G A E Sbjct: 419 YTYMPFGNGVHSCPGSELAKLE 440
>O61387:CP6B7_HELAM Cytochrome P450 6B7 - Helicoverpa armigera (Cotton bollworm)| (Heliothis armigera) Length = 504 Score = 94.7 bits (234), Expect = 1e-18 Identities = 115/478 (24%), Positives = 201/478 (42%), Gaps = 36/478 (7%) Frame = +2 Query: 143 LALYLYYTVWVVPQRLLAGFRRQGIGGPRPSFPYGNMADXXXXXXXXXXXXXXXXXXXIV 322 + LYLY+T R ++++ + GP P+ +GN+ D + Sbjct: 15 VTLYLYFT------RTFNYWKKRNVRGPEPTVFFGNLKDSTLRKKNIGIVMEE------I 62 Query: 323 HDYRPAVLPFYEKWRKEHGPVFTYSMGNVVFL----HVSRPDVVRDINLCVSLDLGKSSY 490 ++ P YEK V Y M L HV + +++D + + Sbjct: 63 YNQFP-----YEK------VVGMYRMTTPCLLVRDFHVIKHIMIKDF------EAFRDRG 105 Query: 491 LKATHEPLFGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVD 670 ++ + E L G+ + ++GE W R P F K+K M LM + A ++ + Sbjct: 106 VEFSKEGL-GQNLFHADGETWRALRNRFTPIFTSGKLKNMFYLMHEGADNFIDHVSKECE 164 Query: 671 KSGGTVDIKIDDDIRAYSADVISRTCFGSSYVKGKKIFLKLRELQKAVSKPNVLAEMT-- 844 K + ++ ++ Y+ IS FG SY L + K +S+P+ E+ Sbjct: 165 KKQ---EFEVHSLLQTYTMSTISSCAFGVSYNSISDKVQTLEIVDKIISEPSYAIELDYM 221 Query: 845 --------GLRFFPT---------------KKNRQAWGLHKQVHRLILEIVKESGEDKNL 955 L PT ++N + G + + LILE+ ++ GE + Sbjct: 222 YPKLLAKLNLSIIPTPVQHFFKSLVDNIISQRNGKPAGRNDFMD-LILEL-RQMGEVTS- 278 Query: 956 LRAILHSASSSKVGLGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQ 1135 L +S ++ + I Y AGYE++A T ++ + L L+ + Q+++ Sbjct: 279 -NKYLDGVTSLEI----TDEVICAQAFVFYVAGYETSATTMSYLIYQLSLNQDVQNKLIA 333 Query: 1136 EVLEV--CGGRPLDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKLGG--VHIPK 1303 EV E + ++++MK L V ETLR+Y + R A ++ ++ G V I K Sbjct: 334 EVDEAIKASDGKVTYDTVKEMKYLNKVFDETLRMYSIVEPLQRKATRDYQIPGTDVVIEK 393 Query: 1304 GVNIYIPVSTMHLDPKLWGPDAKEFNPARF-SDARPQLH--SYLPFGAGARTCLGQGF 1468 + I +H DPK + + K+FNP RF ++ + H +YLPFG G R C+G F Sbjct: 394 DTMVLISPRGIHYDPKYYD-NPKQFNPDRFDAEEVGKRHPCAYLPFGLGQRNCIGMRF 450
>Q04552:CP6B1_PAPPO Cytochrome P450 6B1 - Papilio polyxenes (Black swallowtail butterfly)| Length = 498 Score = 94.7 bits (234), Expect = 1e-18 Identities = 93/351 (26%), Positives = 150/351 (42%), Gaps = 33/351 (9%) Frame = +2 Query: 518 GRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIK 697 G I ++G+ W R P F K+K M+ LM + + + S + Sbjct: 112 GANIFHADGDRWRSLRNRFTPLFTSGKLKSMLPLMSQVGDRFINSID---EVSQTQPEQS 168 Query: 698 IDDDIRAYSADVISRTCFGSSYVKG---------KKIFLKLRELQKAVSKPNVLAEMTGL 850 I + ++ ++ I+ FG + +G K IF + + P +L ++ G Sbjct: 169 IHNLVQKFTMTNIAACVFGLNLDEGMLKTLEDLDKHIFTVNYSAELDMMYPGILKKLNG- 227 Query: 851 RFFPTKKNRQAWGLHKQVHRL----------ILEIVKESGEDKNLLRAILHSASSSKV-- 994 FP ++ L K V + ++++++E E K L + H K Sbjct: 228 SLFPKVVSKFFDNLTKNVLEMRKGTPSYQKDMIDLIQELREKKTLELSRKHENEDVKALE 287 Query: 995 ---GLGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGRP 1165 G+ A+ FI Y AGYE++A T + L +P+ QD++ E+ EV Sbjct: 288 LTDGVISAQMFI------FYMAGYETSATTMTYLFYELAKNPDIQDKLIAEIDEVLSRHD 341 Query: 1166 --LDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKLGG--VHIPKGVNIYIPVST 1333 + + L +M L+ V ETLR YP F R A + G + I KG I + Sbjct: 342 GNITYECLSEMTYLSKVFDETLRKYPVADFTQRNAKTDYVFPGTDITIKKGQTIIVSTWG 401 Query: 1334 MHLDPKLWGPDAKEFNPARFS-----DARPQLHSYLPFGAGARTCLGQGFA 1471 + DPK + P+ ++F+P RF+ D P +YLPF AG R CLG FA Sbjct: 402 IQNDPKYY-PNPEKFDPERFNPENVKDRHP--CAYLPFSAGPRNCLGMRFA 449
>Q9V776:CP317_DROME Probable cytochrome P450 317a1 - Drosophila melanogaster (Fruit fly)| Length = 518 Score = 94.7 bits (234), Expect = 1e-18 Identities = 102/401 (25%), Positives = 172/401 (42%), Gaps = 30/401 (7%) Frame = +2 Query: 488 YLKATHEPLFGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARV 667 Y +PL G + GE+W R+ + P D++ + D + + A+ LL + + Sbjct: 114 YCNQKSDPLSG-DLYALRGESWKEMRQKLDPSLEGDRMSLLYDCLYEEAEQLLLTVNSTL 172 Query: 668 DKSGGTVDIKIDDDIRAYSADVISRTCFGSSYVKGKKI----FLKLRELQKAVSKPNVLA 835 + + I +R Y +++ FG + + K F ++ EL K L Sbjct: 173 MSQPHST-VHIQKIMRRYVLSSLAKCVFGLNAEQRKTYPLEDFEQMTELALNSHKHGYLM 231 Query: 836 EMTGLRFFPTKKNRQAWGLHKQVH----RLILEIVKE---SGE----------DKNLLRA 964 + +RF + + KQ +L+ IV++ SG+ D L Sbjct: 232 NLMMIRFPNFCRMLRMRRTPKQAEEYFIKLLTSIVEQRETSGKPQKDYLQLLIDVKALEF 291 Query: 965 ILHSASSSKVGLGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEV- 1141 I + + K +N + + AGYE TA T ++ L L LHPE Q RVR+EV Sbjct: 292 ITYQYEADKELGAHLQNELAAHADVFLKAGYEQTANTLSYVLYELALHPELQVRVREEVK 351 Query: 1142 --LEVCGGRPLDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKLGG---VHIPKG 1306 +E G + + ++ + + VI ETLR++P ++ R L + + + K Sbjct: 352 KAIERHDGH-ITHEGIKSLSFMGQVINETLRMHPITPYILRRTLNDYAVPDHPKYILVKE 410 Query: 1307 VNIYIPVSTMHLDPKLWGPDAKEFNPARFSDARPQLH---SYLPFGAGARTCLGQGFATA 1477 + + IP +H DP ++ PD +EF P R+S R L ++ FG GAR+C+G FA Sbjct: 411 LFLIIPTHAIHHDPDIY-PDPEEFKPDRWSGPRDSLQEQGTWFGFGVGARSCIGIQFAQL 469 Query: 1478 EXXXXXXXXXXXFALRLSPLYQHSPALKLIVEPEFGVDITL 1600 + AL LS K ++ E G+ +TL Sbjct: 470 Q-------LRLALALLLSEYEFSLNTRKPLINLEDGIALTL 503
>Q9VYQ7:CP311_DROME Probable cytochrome P450 311a1 - Drosophila melanogaster (Fruit fly)| Length = 483 Score = 94.4 bits (233), Expect = 1e-18 Identities = 91/390 (23%), Positives = 162/390 (41%), Gaps = 23/390 (5%) Frame = +2 Query: 506 EPLFGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGT 685 EPL G G+L S+G W QR+++ P F ++ + + L+ R+ + G Sbjct: 104 EPLIGNGLLISHGAHWTRQRRLLTPAFQPQLLRSFAPAIGGHVERLV----GRLGATRGA 159 Query: 686 VDIKIDDDIRAYSADVISRTCFGSSY----VKGKKIFLKLRELQKAVSKPNVLAEMTGLR 853 +++ + + A D I T G+ V I K + K + ++ Sbjct: 160 F-LEVTEPLFACLLDAIVDTSMGAQLDTQSVDHSPIIQAFHLSSKLLFKRMINPLLSSDW 218 Query: 854 FFPTKK-----NRQAWGLHKQVHRLILEIVKE-------SGEDKNLLRAILHSASSSKVG 997 F + + Q +H Q+ +I + KE +G NLL +L + G Sbjct: 219 IFQRTQLWRDLDEQLQVIHSQMESVIEKRAKELLDMGEPAGRAHNLLDTLLLAKFE---G 275 Query: 998 LGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGRPLDSQ 1177 + I D + FAG ++T ++ L L PE Q R+R+E+ +V D Sbjct: 276 QSLSRREIRDEINTFVFAGVDTTTAAMSFVLYALAKFPETQTRLRKELQDVALDETTDLD 335 Query: 1178 SLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLW 1357 +L + L +I+E LRLY R Q ++GG GV ++I + + D K + Sbjct: 336 ALNGLPYLEALIKEVLRLYTIVPTTGRQTTQSTEIGGRTYCAGVTLWINMYGLAHD-KEY 394 Query: 1358 GPDAKEFNPARF----SDARPQLHSYLPFGAGARTCLGQGFATAEXXXXXXXXXXXFALR 1525 PD F P R+ P SY+PF G C+G+ ++ F + Sbjct: 395 YPDPYAFKPERWLPEDGAVAPPAFSYIPFSGGPHVCIGRRYSLLLMKLLTARLVREFQME 454 Query: 1526 LSPLYQHSP---ALKLIVEPEFGVDITLTK 1606 LSP + +P +++++ + G++++ K Sbjct: 455 LSP--EQAPLRLEAQMVLKAQQGINVSFLK 482
>Q07217:CP11A_ONCMY Cytochrome P450 11A1, mitochondrial precursor - Oncorhynchus mykiss| (Rainbow trout) (Salmo gairdneri) Length = 514 Score = 94.4 bits (233), Expect = 1e-18 Identities = 90/391 (23%), Positives = 167/391 (42%), Gaps = 27/391 (6%) Frame = +2 Query: 524 GILKSNGEAWAHQRKIIAPEFFLDKVKG-MVDLMVDSAQTLLEPWEARVDKSGG---TVD 691 G+L NGE W R I+ E KV G V L+ + Q + ++++SG T D Sbjct: 136 GVLLKNGEDWRSNRVILNREVISPKVLGNFVPLLDEVGQDFVARVHKKIERSGQDKWTTD 195 Query: 692 IKIDDDIRAYSADVISRTCFGS------SYVKGKK------IFLKLRELQKAVSKPNVLA 835 + ++ Y+ + + +G Y+ + I L + + P + Sbjct: 196 LS--QELFKYALESVGSVLYGERLGLMLDYINPEAQHFIDCISLMFKTTSPMLYIPPAML 253 Query: 836 EMTGLRFFPTKKNRQAW-GLHKQVHRLILEIVKESGEDKN-------LLRAILHSASSSK 991 G + + + + +AW G+ Q R I I + +D N +L ++L K Sbjct: 254 RRVGAKIW--RDHVEAWDGIFNQADRCIQNIYRTMRQDTNTHGKYPGVLASLL---MLDK 308 Query: 992 VGLGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGRPLD 1171 + + + + + + + G ++T++T W L L HP+ Q+ +R EV + Sbjct: 309 LSIEDIKASVTE----LMAGGVDTTSITLLWTLYELARHPDLQEELRAEV--AVARQSTQ 362 Query: 1172 SQSLQKMKNLTMV---IQETLRLYPAGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHL 1342 LQ +K + +V ++ETLRL+P + R +E+ + HIP G + + + M Sbjct: 363 GDMLQMLKMIPLVKGALKETLRLHPVAVSLQRYITEEIVIQNYHIPCGTLVQLGLYAMGR 422 Query: 1343 DPKLWGPDAKEFNPARFSDARPQLHSYLPFGAGARTCLGQGFATAEXXXXXXXXXXXFAL 1522 DP ++ P +++ P+R+ Q L FG G R CLG+ A E F + Sbjct: 423 DPDVF-PRPEKYLPSRWLRTENQYFRSLGFGFGPRQCLGRRIAETEMQLFLIHMLENFRV 481 Query: 1523 RLSPLYQHSPALKLIVEPEFGVDITLTKVQT 1615 + +LI+ PE + +TL +++ Sbjct: 482 DKQRQVEVHSTFELILLPEKPILLTLKPLKS 512
>Q9STL0:C71AN_ARATH Cytochrome P450 71A23 - Arabidopsis thaliana (Mouse-ear cress)| Length = 483 Score = 94.4 bits (233), Expect = 1e-18 Identities = 84/386 (21%), Positives = 153/386 (39%), Gaps = 20/386 (5%) Frame = +2 Query: 374 HGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRGILKSN---- 541 +GP+ G+V + S + RD+ L + +F + + KS Sbjct: 60 YGPLMLLHFGSVPVIVASTAEAARDV-----LKTHDRVFASRPRSKIFEKLLYKSRNMAS 114 Query: 542 ---GEAWAHQRKIIAPEFFLDK-VKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDD 709 GE W + + +K V+ D+ + ++E + + + + Sbjct: 115 APYGEYWRQMKSVSVLHLLSNKMVRSFQDVRQEEITLMME-----TIRKSSSKPVNLSKI 169 Query: 710 IRAYSADVISRTCFGSSYVKGKKIFLKLRELQKAVSKPNV------LAEMTGLRFFPTKK 871 + + + DVI R G Y G + L + + + LA + + Sbjct: 170 LSSLTNDVICRVALGRKYGVGTDFKELIDRLMRQLGTFTIGSYVPWLAWTDWVSGLEARL 229 Query: 872 NRQAWGLHKQVHRLILEIVKESGEDKNLLRAILHSASSSKVGLGEAENFIVDNCKSIYFA 1051 + A K + R++ + G+ + + +L + G I + Sbjct: 230 EKTANDFDKLLERIVQDHEDGDGDKTDFVDVLLAAQRDKSFGFDIDRLSIKAIVLDAFVG 289 Query: 1052 GYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGRPLDSQS-LQKMKNLTMVIQETLR 1228 G ++++ W + L HP ++++EV +C G+ S+ +Q M+ L V++E LR Sbjct: 290 GTDTSSTLVEWEMTELLRHPTCLKKLQEEVRTICKGKSSVSEDDIQGMEYLKAVVKEALR 349 Query: 1229 LYP-AGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARF---- 1393 L+P V + Q+++L HIP G + + + + + WGPDA EF P R Sbjct: 350 LHPPVPLMVPHQSTQDVRLRDNHIPAGTQVIVNLWAVGREAATWGPDANEFRPERHLESP 409 Query: 1394 SDARPQLHSYLPFGAGARTCLGQGFA 1471 SD R Q +PFGAG R C G FA Sbjct: 410 SDFRGQDFELIPFGAGRRMCPGISFA 435
>Q95036:CP6B5_PAPGL Cytochrome P450 6B5 - Papilio glaucus (Tiger swallowtail butterfly)| Length = 476 Score = 94.0 bits (232), Expect = 2e-18 Identities = 117/469 (24%), Positives = 194/469 (41%), Gaps = 29/469 (6%) Frame = +2 Query: 149 LYLYYTVWVVPQRLLAGFRRQGIGGPRPSFPYGNMADXXXXXXXXXXXXXXXXXXXIVHD 328 LYLY+T R ++ + + GP P+ +GN+ + ++ Sbjct: 15 LYLYFT------RNFNYWKDRNVVGPEPTVFFGNIMESVIRRKH------------LIMI 56 Query: 329 YRPAVLPFYEKWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHE 508 Y+ YE + KE V Y M L + DV++ + + DL ++ + E Sbjct: 57 YKD----IYEAFPKEK-VVGIYRMTTPCLL-LRDLDVIKHV-MIKDFDLFNDRGVEFSEE 109 Query: 509 PLFGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTV 688 L G I ++G+ W R+ P F K+K M++LM D ++ E DK Sbjct: 110 GL-GLNIFHADGDRWRVLRQCFTPLFTSGKLKNMLNLMSDRGDKFIKMVEKICDKEPEQQ 168 Query: 689 DIKID-----------------DDIRAYSADVISRTCFGSSYVKGKKIFLKLRELQKAVS 817 I + D+ + D + F +SY G +I + + K ++ Sbjct: 169 IIPLVRKFTMASITTCAFGMELDEEMIETLDKLDSLIFTTSY--GNEIDMMYPGILKKLN 226 Query: 818 KPNVLAEMTGLRFFPTKKN--RQAWGL---HKQVHRLILEIVKESGEDKNLLRAILHSAS 982 ++ ++M F K Q G K + LILE+ K + + + Sbjct: 227 S-SLFSKMIAPFFDNLTKTIIEQRGGKPTNRKDLMDLILEL-----RQKKAIEPMKKTHD 280 Query: 983 SSKVGLGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGR 1162 L ++ I Y AGYE++A T ++ L L +P+ Q++V EV E Sbjct: 281 EQVTTLELTDSVIAAQTFIFYAAGYETSASTMSFLLFELAENPDIQEKVIAEVDETLKRH 340 Query: 1163 --PLDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKLGGVHIP--KGVNIYIPVS 1330 + +L +M LT V ETLR YP + R A + + G ++ KG + + Sbjct: 341 NGEITYDTLSEMTYLTQVFHETLRKYPVADILLRNAKADYAVPGTNVTLKKGQTVVVSGF 400 Query: 1331 TMHLDPKLWGPDAKEFNPARFSDARPQLH---SYLPFGAGARTCLGQGF 1468 +H DPK + PD ++F+P RFS + +Y+PFGAG R CLG F Sbjct: 401 GIHYDPKYY-PDPEKFDPERFSPENVRNRHPCAYIPFGAGQRKCLGMRF 448
>Q9GMC8:CP17A_FELCA Cytochrome P450 17A1 - Felis silvestris catus (Cat)| Length = 508 Score = 94.0 bits (232), Expect = 2e-18 Identities = 106/441 (24%), Positives = 193/441 (43%), Gaps = 35/441 (7%) Frame = +2 Query: 359 KWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFG--RGI- 529 K +K++GP++++ +G + V + +++ + + ++ T + L +GI Sbjct: 55 KLQKKYGPIYSFRLGTKTTVMVGDHQLAKEVLVKKGKEFSGRPHV-VTLDILSDNQKGIA 113 Query: 530 LKSNGEAWAHQRKIIAPEFFLDKVKGM-VDLMVDSAQTLLEPWEARVDKSGGTVDIKIDD 706 +G +W RK+ F L K ++ ++ +LL A D G ++D+ + Sbjct: 114 FADHGASWQMHRKLALATFALFKDGDQRLEKIICREISLLCDNLAMQD--GQSIDLYLPL 171 Query: 707 DIRAYSADVISRTCFGSSYVKGK---KIFLKLRE-LQKAVSKPNVLAEMTGLRFFPTKKN 874 + ++I CF SS+ G KI E + K + K N++ L+ FP K Sbjct: 172 FLAV--TNIICLICFNSSFKNGDPALKIIQNYNEGILKTLGKDNLVDIFPVLKIFPNKTL 229 Query: 875 RQAWGLHKQVHRLILEIVKESGED------KNLLRAILHS--------ASSSKVGLGEAE 1012 + K L+ EI+++ E+ N+L ++ + A+S + ++ Sbjct: 230 EKMKNYVKNRDELLREILEKHKENFSNDSITNMLDVLIQARMNSDNNGAASDQDSKLLSD 289 Query: 1013 NFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCG-GRPLDSQSLQK 1189 I+ I+ AG E+T W + L HP+ ++++E+ + G R + Sbjct: 290 KHILTTIGDIFGAGVETTTSVVRWTVAFLLHHPQLYKKLQEEIDQNIGFSRTPTMSDRNQ 349 Query: 1190 MKNLTMVIQETLRLYP-AGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLW-GP 1363 + L I+E LR+ P A + A+ + +G + KG N+ I + +H + K W P Sbjct: 350 LILLEATIREVLRIRPVAPTLIPHKAIMDSSIGEFAVDKGTNVIINLWALHHNEKEWYRP 409 Query: 1364 DAKEFNPARFSD-ARPQLHS----YLPFGAGARTCLGQGFATAEXXXXXXXXXXXFALRL 1528 D +F P RF D R QL S YLPFGAG R+CLG+ A E F L + Sbjct: 410 D--QFMPERFLDPTRSQLISPSLSYLPFGAGPRSCLGESLARQEVFLFMAWLLQRFDLEV 467 Query: 1529 S-----PLYQHSPALKLIVEP 1576 P + +P + ++ P Sbjct: 468 PDDGQLPHLEGNPTVVFLIAP 488
>O65790:C81F1_ARATH Cytochrome P450 81F1 - Arabidopsis thaliana (Mouse-ear cress)| Length = 500 Score = 94.0 bits (232), Expect = 2e-18 Identities = 94/407 (23%), Positives = 179/407 (43%), Gaps = 25/407 (6%) Frame = +2 Query: 320 VHDYRPAVLPFYEKWRKEHGPVFTYSMGNVVFLHVSRPDVVR-------DINLCVSLDLG 478 +H +P + +++ ++GP+F+ G+ + ++ P + + DI L S L Sbjct: 41 LHLMKPPIHRLLQRYSNQYGPIFSLRFGSRRVVVITSPSLAQESFTGQNDIVLS-SRPLQ 99 Query: 479 KSSYLKATHEPLFGRGILKSNGEAWAHQRKIIAPEFFLD-KVKGMVDLMVDSAQ---TLL 646 ++ A + G G+ W + R+I + E ++ + D T L Sbjct: 100 LTAKYVAYNHTTVGTA---PYGDHWRNLRRICSQEILSSHRLINFQHIRKDEILRMLTRL 156 Query: 647 EPWEARVDKSGGTVDIKIDDDIRAYSADVISRTCFGSSY----VKGKK---IFLKLRELQ 805 + ++S I+++ + + + I R G Y V K+ +F KL Sbjct: 157 SRYTQTSNESNDFTHIELEPLLSDLTFNNIVRMVTGKRYYGDDVNNKEEAELFKKLVYDI 216 Query: 806 KAVSKPNVLAE-MTGLRFFPTKKNRQAWGLHKQVHRLILEIVKESGEDKNLLRAILHSAS 982 S N A+ + L+ F K ++ + K + ++ ++ E DK + H S Sbjct: 217 AMYSGANHSADYLPILKLFGNKFEKEVKAIGKSMDDILQRLLDECRRDKEGNTMVNHLIS 276 Query: 983 SSKVGLGEAENFIVDNCK-SIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCG- 1156 + + I+ S+ AG E++AVT W + L +PE ++ R E+ E G Sbjct: 277 LQQQQPEYYTDVIIKGLMMSMMLAGTETSAVTLEWAMANLLRNPEVLEKARSEIDEKIGK 336 Query: 1157 GRPLDSQSLQKMKNLTMVIQETLRLYPAGAF-VSRMALQELKLGGVHIPKGVNIYIPVST 1333 R +D + + L V+ ET RL+P F + R ++K+GG +P+ + + Sbjct: 337 DRLIDESDIAVLPYLQNVVSETFRLFPVAPFLIPRSPTDDMKIGGYDVPRDTIVMVNAWA 396 Query: 1334 MHLDPKLWGPDAKEFNPARFSD---ARPQLHSYLPFGAGARTCLGQG 1465 +H DP++W + ++FNP R++D + ++ +PFG G RTC G G Sbjct: 397 IHRDPEIW-EEPEKFNPDRYNDGCGSDYYVYKLMPFGNGRRTCPGAG 442
>Q9LXM3:C71BZ_ARATH Cytochrome P450 71B38 - Arabidopsis thaliana (Mouse-ear cress)| Length = 500 Score = 94.0 bits (232), Expect = 2e-18 Identities = 100/419 (23%), Positives = 179/419 (42%), Gaps = 39/419 (9%) Frame = +2 Query: 320 VHDYRPAVLPFYEKWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKA 499 +H + + K +E+GPV +G V + VS + ++ + DL + K Sbjct: 41 LHQLGKLLYKSFHKISQEYGPVVLLRLGVVPVIVVSSKEGAEEV--LKTHDLETCTRPKT 98 Query: 500 THEPLFGRGILKSN----GEAWAHQRKIIAPEFF-LDKVKGMVDLMVDSAQTLLEPWEAR 664 LF G+ W RKI E F + K+K + + ++ L++ Sbjct: 99 AATGLFTYNFKDIGFAPFGDDWREMRKITTLELFSVKKLKSFRYIREEESELLVKKISKS 158 Query: 665 VDKS-GGTVDIKIDDDIRAYSADVISRTCFGSSYVKGKKIFLKLRELQKAVSKPNV-LAE 838 VD++ +VD++ + +++A +I R FG ++ + F+ + ++++ V + L Sbjct: 159 VDETQNSSVDLR--KVLFSFTASIICRLAFGQNFHQCD--FVDMEKVEELVLESEANLGT 214 Query: 839 MTGLRFFPTKKNRQAW------GLHKQVHRLILEIVK-------------ESGEDKNLLR 961 FFP W G H +V++ ++ + + +++ Sbjct: 215 FAFADFFPG-----GWLIDRISGQHSRVNKAFYKLTNFYKHVIDDHLKTGQPQDHSDIVS 269 Query: 962 AILH------SASSSKVGLGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQD 1123 +L A S KV + + D I+ AG A T W L L HP Sbjct: 270 VMLDMINKPTKADSFKVTYDHLKGVMSD----IFLAGVNGGANTMIWTLTELSRHPRVMK 325 Query: 1124 RVRQEVLEVCGGRP--LDSQSLQKMKNLTMVIQETLRLYP-AGAFVSRMALQELKLGGVH 1294 ++++E+ + G + + L+K++ L +V+ ET RL+P A + R+ + ++K+ G + Sbjct: 326 KLQEEIRAMLGPNKERITEEDLEKVEYLKLVMVETFRLHPPAPLLLPRLTMSDIKIQGYN 385 Query: 1295 IPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARFSDA----RPQLHSYLPFGAGARTCLG 1459 IPK I I + DPK W EF P RF D+ + Q LPFGAG R C G Sbjct: 386 IPKNTMIQINTYAIGRDPKYW-KQPGEFIPERFLDSPIDYKGQHFELLPFGAGRRICPG 443
>O16805:CP4D1_DROSI Cytochrome P450 4d1 - Drosophila simulans (Fruit fly)| Length = 512 Score = 93.6 bits (231), Expect = 2e-18 Identities = 89/358 (24%), Positives = 152/358 (42%), Gaps = 33/358 (9%) Frame = +2 Query: 506 EPLFGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGT 685 EP G+L S G W +RKII P F + VD+ ++ LL E K G + Sbjct: 112 EPWLKEGLLVSRGRKWHKRRKIITPAFHFKILDQFVDVFEKGSRDLLRNMEQDRLKHGDS 171 Query: 686 VDIKIDDDIRAYSADVISRTCFG----------SSYVKGKKIFLKLRELQKAVSKPNVLA 835 + D I + D I T G S YV+ K + L K + Sbjct: 172 -GFSLYDWINLCTMDTICETAMGVSINAQSNADSEYVQAVKTISMV--LHKRMFNILYRF 228 Query: 836 EMTGLRFFPTKKNRQAWG-LHKQVHRLIL----EIVKESGEDKNLL----------RAIL 970 ++T + + ++A LH+ ++I+ E+++E ++ A L Sbjct: 229 DLTYMLTPLARAEKKALNVLHQFTEKIIVQRREELIREGSSQESSKDDADVGAKRKMAFL 288 Query: 971 HSASSSKVGLGEAENF-IVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLE 1147 S V N I + + F G+++T+ + + HPE Q + +E+ Sbjct: 289 DILLQSTVDERPLSNLDIREEVDTFMFEGHDTTSSALMFFFYNIATHPEAQKKCFEEIRS 348 Query: 1148 VCGG---RPLDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKLGGVHIPKGVNIY 1318 V G P+ + L ++ + + ++ETLR+YP+ + R L++ ++ G IP G NI Sbjct: 349 VVGNDKSTPVSYELLNQLHYVDLCVKETLRMYPSVPLLGRKVLEDCEINGKLIPAGTNIG 408 Query: 1319 IPVSTMHLDPKLWGPDAKEFNPARF----SDARPQLHSYLPFGAGARTCLGQGFATAE 1480 I + +L+ + F P RF + + ++Y+PF AG R C+GQ FA E Sbjct: 409 ISPLYLGRREELFS-EPNSFKPERFDVVTTAEKLNPYAYIPFSAGPRNCIGQKFAMLE 465
>Q9LIP5:C71BW_ARATH Cytochrome P450 71B35 - Arabidopsis thaliana (Mouse-ear cress)| Length = 500 Score = 93.6 bits (231), Expect = 2e-18 Identities = 97/402 (24%), Positives = 168/402 (41%), Gaps = 32/402 (7%) Frame = +2 Query: 344 LPFYEKWR--KEHGPVFTYSMGNVVFLHVSRPDVVR------DINLCVSLDLGKSSYLKA 499 LP W+ K++GPV +G V + VS D R D++ C L L Sbjct: 49 LPHQTLWKLSKKYGPVMHLMLGRVPTVVVSSSDTARQVLRVHDLHCCTRPSLSGPRELSY 108 Query: 500 THEPLFGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSG 679 + + + W RK+ E F K + + D + + + ++ + + Sbjct: 109 NYLDI----AFSPYDDYWKEVRKLCVQELFSTKQVHSIQPIKD--EEVKKMIDSIAESAS 162 Query: 680 GTVDIKIDDDIRAYSADVISRTCFGSSYV-------KGKKIFLKLRELQKAVSKPN---- 826 + +++ + V+ RT FG S+ + KI + E+ + S + Sbjct: 163 QKNPVNLNNKCLELTVSVVCRTAFGVSFEGTVLNSDRFNKIVREALEMLGSFSAADFIPY 222 Query: 827 ---VLAEMTGLRFFPTKKNRQAWGLHKQVHRLILEIVKESGED--KNLLRAILHSA--SS 985 ++ +TGL+ + R +Q+ L E KE ED LLR A + Sbjct: 223 VGWIIDVLTGLQGRRERSKRDLNAFFEQMFDLHKEGKKEGNEDFVDLLLRLEKEEAVLGN 282 Query: 986 SKVGLGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGRP 1165 K+ + ++D + AG +++A+T W + L +P +V+ E+ G R Sbjct: 283 DKLTRNHIKAILLD----VLLAGIDTSAITMTWAMTELARNPRVMKKVQSEIRTQMGNRS 338 Query: 1166 LDS-QSLQKMKNLTMVIQETLRLYP-AGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMH 1339 + S + + +++ L MVI+ET RL+P + R A+ E + G IP +++ V + Sbjct: 339 MISFEDMDQLEYLKMVIKETWRLHPTTPLLLPREAMSEFDINGYTIPVKTRLHVNVWAIG 398 Query: 1340 LDPKLWGPDAKEFNPARFS----DARPQLHSYLPFGAGARTC 1453 DP W D + F P RF DA+ Q LPFG G R C Sbjct: 399 RDPDTW-KDPEVFLPERFMDNNIDAKGQHFELLPFGGGRRIC 439
>Q9STL1:C71AM_ARATH Cytochrome P450 71A22 - Arabidopsis thaliana (Mouse-ear cress)| Length = 490 Score = 93.6 bits (231), Expect = 2e-18 Identities = 99/391 (25%), Positives = 159/391 (40%), Gaps = 25/391 (6%) Frame = +2 Query: 374 HGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLF-GRGI-LKSNGE 547 +GP+ G V L VS DV RDI K + + R + L GE Sbjct: 63 YGPLMLLRFGLVPVLVVSSADVARDILKTYDRVFASRPRSKIFEKIFYEARDVALAPYGE 122 Query: 548 AWAHQRKIIAPEFFLDK-VKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAYS 724 W + + +K V+ ++ + ++E ++ KS ++ + + + + + + Sbjct: 123 YWRQMKSVCVLHLLTNKMVRSFRNVRQEEISLMME----KIQKSS-SLQVNLSELLGSLT 177 Query: 725 ADVISRTCFGSSYVKGKKIFLKLRELQKAVSKPNVLAEMTGLRFFPTKKNRQAW-----G 889 DVISR G Y +EL K ++K +L E + P AW G Sbjct: 178 NDVISRVALGRKYSDETDF----KELMKRLTK--LLGEFCVGTYVPWL----AWIDWISG 227 Query: 890 LHKQVHRL------ILEIVKESGEDKNLLRA-----ILHSASSSKVGLGEAENFIVDNCK 1036 L Q+ + LE V + ED + R +L VG I Sbjct: 228 LDGQLKKTGNDLDEFLEKVVQDHEDGDAQRTDFVDVLLRIQREKSVGFEIDRLSIKAIIL 287 Query: 1037 SIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVC-GGRPLDSQSLQKMKNLTMVI 1213 + G +++ W + L PE +R+++EV +C G + ++ M L VI Sbjct: 288 DVVVGGTDTSYALMEWAMTELLHRPECLNRLQEEVRTICKGNSSVSEDDIKDMNYLKAVI 347 Query: 1214 QETLRLYPA-GAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPAR 1390 +ET+RL+P V + Q+++LG HIP G + I + + WGPDA++F P R Sbjct: 348 KETMRLHPPLPLMVPHESTQDVRLGDYHIPAGTQVMINAWAIGREAATWGPDAEKFRPER 407 Query: 1391 F----SDARPQLHSYLPFGAGARTCLGQGFA 1471 D R +PFGAG R C FA Sbjct: 408 HLNSSVDFRGHNFELIPFGAGRRICPAISFA 438
>O46054:C4AE1_DROME Cytochrome P450 4ae1 - Drosophila melanogaster (Fruit fly)| Length = 496 Score = 93.6 bits (231), Expect = 2e-18 Identities = 94/383 (24%), Positives = 174/383 (45%), Gaps = 22/383 (5%) Frame = +2 Query: 518 GRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIK 697 G G+L S G+ W RKII P F ++ V++ + L+E S G + Sbjct: 114 GDGLLLSRGKEWHTMRKIITPTFHFSILEQFVEVFDRQSSILVERLRTL---SYGNEVVN 170 Query: 698 IDDDIRAYSADVISRTCFG---SSYVKGKKIFLKLRELQKAVS----KPNVLAEMTGLRF 856 I + + D+I+ T G + ++ +++L ++ +P++L Sbjct: 171 IYPLVGLAALDIITETAMGVNVDAQGADSEVVHAVKDLTNILATRFMRPHLLFPHLFRLC 230 Query: 857 FPTKKNRQAWG---LHKQVHRLILE----IVKESGEDKNLL-RAILHSASSSKV-GLGEA 1009 +P+ +Q G LH+ + +I + + +E+ +DK A+L + + V G Sbjct: 231 WPSGFRKQQAGVICLHEFTNGIIEQRRRLLAREANQDKPTKPHALLDTLLRATVDGQPLT 290 Query: 1010 ENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGG---RPLDSQS 1180 + I D + F G+++T ++CL LL H Q ++ +E+ G R + Sbjct: 291 DKQIRDEVNTFIFEGHDTTTSAVSFCLYLLSRHEAVQQKLFEELRMHYGQDLFRGVILSD 350 Query: 1181 LQKMKNLTMVIQETLRLYPAGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWG 1360 + L+ V++E+LRLYP V+R ++L + +IP G N+ + + + D ++ Sbjct: 351 FATLPYLSCVVKESLRLYPPIPAVARCLEKDLVIDEGYIPVGTNVVVLLWQLLRDEAIF- 409 Query: 1361 PDAKEFNPAR-FSDARPQL--HSYLPFGAGARTCLGQGFATAEXXXXXXXXXXXFALRLS 1531 D F P R + P+L +SY+PF AG R C+GQ FA E + L L Sbjct: 410 TDPLVFQPERHLGEEAPRLSPYSYIPFSAGPRNCIGQKFALLEMKTMVTKVIRHYQL-LP 468 Query: 1532 PLYQHSPALKLIVEPEFGVDITL 1600 P++K+++ + GV++ L Sbjct: 469 MGADVEPSIKIVLRSKSGVNVGL 491
>Q27902:CP6B4_PAPGL Cytochrome P450 6B4 - Papilio glaucus (Tiger swallowtail butterfly)| Length = 500 Score = 93.2 bits (230), Expect = 3e-18 Identities = 116/469 (24%), Positives = 193/469 (41%), Gaps = 29/469 (6%) Frame = +2 Query: 149 LYLYYTVWVVPQRLLAGFRRQGIGGPRPSFPYGNMADXXXXXXXXXXXXXXXXXXXIVHD 328 LY Y+T R ++ + + GP P+ +GN+ + ++ Sbjct: 15 LYFYFT------RNFNYWKDRNVVGPEPTVFFGNIMESVIRRKH------------LIMI 56 Query: 329 YRPAVLPFYEKWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHE 508 Y+ YE + KE V Y M L + DV++ + + DL ++ + E Sbjct: 57 YKD----IYEAFPKEK-VVGIYRMTTPCLL-LRDLDVIKHV-MIKDFDLFNDRGVEFSEE 109 Query: 509 PLFGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTV 688 L G I ++G+ W R+ P F K+K M++LM D ++ E DK Sbjct: 110 GL-GLNIFHADGDRWRVLRQCFTPLFTSGKLKNMLNLMSDRGDKFIKMVEKFCDKEPEQQ 168 Query: 689 DIKID-----------------DDIRAYSADVISRTCFGSSYVKGKKIFLKLRELQKAVS 817 I + D+ + D + F +SY G +I + + K ++ Sbjct: 169 IIPLVRKFTMASITTCAFGMELDEEMIETLDKLDSLIFTTSY--GNEIDMMYPGILKKLN 226 Query: 818 KPNVLAEMTGLRFFPTKKN--RQAWGL---HKQVHRLILEIVKESGEDKNLLRAILHSAS 982 ++ ++M F K Q G K + LILE+ K + + + Sbjct: 227 S-SIFSKMIAPFFDNLTKTIIEQRGGKPTNRKDLMDLILEL-----RQKKAIEPMKKTHD 280 Query: 983 SSKVGLGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGR 1162 L ++ I Y AGYE++A T ++ L L +P+ Q++V EV E Sbjct: 281 EQVTTLELTDSVIAAQTFIFYAAGYETSASTMSFLLFELAENPDIQEKVIAEVDETLKRH 340 Query: 1163 --PLDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKLGGVHIP--KGVNIYIPVS 1330 + +L +M LT V ETLR YP + R A + + G ++ KG + + Sbjct: 341 NGEITYDTLSEMTYLTQVFHETLRKYPVADILLRNAKADYAVPGTNVTLKKGQTVVVSGF 400 Query: 1331 TMHLDPKLWGPDAKEFNPARFSDARPQLH---SYLPFGAGARTCLGQGF 1468 +H DPK + PD ++F+P RFS + +Y+PFGAG R CLG F Sbjct: 401 GIHYDPKYY-PDPEKFDPERFSPENVRNRHPCAYIPFGAGQRKCLGMRF 448
>Q12589:CP52K_CANMA Cytochrome P450 52A11 - Candida maltosa (Yeast)| Length = 519 Score = 93.2 bits (230), Expect = 3e-18 Identities = 105/381 (27%), Positives = 161/381 (42%), Gaps = 32/381 (8%) Frame = +2 Query: 509 PLFGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTV 688 PL G+GI +GE W H R ++ P+F D+V G V ++ Q L + + K+ G+ Sbjct: 127 PLLGKGIFTLDGEGWKHSRAMLRPQFSRDQV-GHVKMLEPHFQLL----KKHIIKNKGSF 181 Query: 689 DIKIDDDIRAYSADVISRTCFGSSY--VKGKKIFLKLRELQKAVSKPNVLAEMTGLRFFP 862 I + ++ D + FG S +K + I E+ A K A + Sbjct: 182 -FDIQELFFRFTVDSATEFLFGESVSSLKDESIGYDQEEIDFAGRKDFAEAFNKSQVYLS 240 Query: 863 TKKNRQA--WGLHKQVHRLILEIVKESGED--KNLLRAILHSAS--SSKVGLGEAEN--- 1015 T+ Q W ++ + +IV + + K L A SS + L E Sbjct: 241 TRSLLQLLYWLVNSSDFKRCNKIVHKFSDYYIKKALTATPEELEKHSSYIFLYELAKQTR 300 Query: 1016 ---FIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGRP------L 1168 + D +I AG ++TA ++ + LG +PE ++R+E+ + G P + Sbjct: 301 DPIVLRDQSLNILLAGRDTTAGLLSFAVFELGRNPEVWSKLREEIGDKFGLDPDSRIEDI 360 Query: 1169 DSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKL---GG------VHIPKGVNIYI 1321 + L+ + L VI ETLRLYP+ R A L GG + + KG + Sbjct: 361 SFELLKLCEYLKAVINETLRLYPSVPRNGRFAAANTTLPHGGGPDGMSPILVRKGQTVMY 420 Query: 1322 PVSTMHLDPKLWGPDAKEFNPARF--SDARPQLHSYLPFGAGARTCLGQGFATAEXXXXX 1495 V + D K +G DA EF P R+ + R ++LPF G R CLGQ FA E Sbjct: 421 SVYALQRDEKYYGKDANEFRPERWFEPEVRKLGWAFLPFNGGPRICLGQQFALTEASYVL 480 Query: 1496 XXXXXXF-ALRLSPLYQHSPA 1555 F L LSP + PA Sbjct: 481 VRLIQSFETLELSPDAPYPPA 501
>P20813:CP2B6_HUMAN Cytochrome P450 2B6 - Homo sapiens (Human)| Length = 491 Score = 93.2 bits (230), Expect = 3e-18 Identities = 112/417 (26%), Positives = 186/417 (44%), Gaps = 34/417 (8%) Frame = +2 Query: 332 RPAVLPFYEKWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEP 511 R +L + ++R+++G VFT +G + + + +R+ L + A +P Sbjct: 48 RRGLLKSFLRFREKYGDVFTVHLGPRPVVMLCGVEAIREA-LVDKAEAFSGRGKIAMVDP 106 Query: 512 LF-GRGILKSNGEAWAHQRKIIAP---EFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSG 679 F G G++ +NG W R+ +F + K + + + + + AQ L+E E R K G Sbjct: 107 FFRGYGVIFANGNRWKVLRRFSVTTMRDFGMGK-RSVEERIQEEAQCLIE--ELRKSK-G 162 Query: 680 GTVDIKIDDDIRAYSADVISRTCFGSSYVKGKKIFLKLREL--QKAVSKPNVLAEMTGL- 850 +D ++ +A++I FG + + FLK+ L Q +V ++ L Sbjct: 163 ALMDPTFL--FQSITANIICSIVFGKRFHYQDQEFLKMLNLFYQTFSLISSVFGQLFELF 220 Query: 851 ----RFFPTKKNRQAWGLHKQVHRLILEIVKESGED-------------KNLLRA-ILHS 976 ++FP G H+QV++ + EI G K+L+ +LH Sbjct: 221 SGFLKYFP--------GAHRQVYKNLQEINAYIGHSVEKHRETLDPSAPKDLIDTYLLHM 272 Query: 977 ASSSKVGLGEAENFIVD-NCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVC 1153 E + ++ N S++FAG E+T+ T + +L+ +P +RV +E+ +V Sbjct: 273 EKEKSNAHSEFSHQNLNLNTLSLFFAGTETTSTTLRYGFLLMLKYPHVAERVYREIEQVI 332 Query: 1154 GG-RPLDSQSLQKMKNLTMVIQETLR---LYPAGAFVSRMALQELKLGGVHIPKGVNIYI 1321 G RP + KM VI E R L P G V + Q G IPK +++ Sbjct: 333 GPHRPPELHDRAKMPYTEAVIYEIQRFSDLLPMG--VPHIVTQHTSFRGYIIPKDTEVFL 390 Query: 1322 PVSTMHLDPKLWG-PDAKEFNPARFSDARPQL---HSYLPFGAGARTCLGQGFATAE 1480 +ST DP + PDA FNP F DA L +++PF G R CLG+G A AE Sbjct: 391 ILSTALHDPHYFEKPDA--FNPDHFLDANGALKKTEAFIPFSLGKRICLGEGIARAE 445
>O65788:C71B2_ARATH Cytochrome P450 71B2 - Arabidopsis thaliana (Mouse-ear cress)| Length = 502 Score = 93.2 bits (230), Expect = 3e-18 Identities = 97/415 (23%), Positives = 173/415 (41%), Gaps = 40/415 (9%) Frame = +2 Query: 353 YEKWRKEHGPVFTYSMGNVVFLHVSRPDVVR------DINLCV---SLDLGKSSY--LKA 499 + K ++GP+ +G+V + +S + D+ C ++ GK SY Sbjct: 55 FHKLSIKYGPLVFLRLGSVPVVVISSSEAAEAVLKTNDLECCSRPKTVGSGKLSYGFKDI 114 Query: 500 THEPLFGRGILKSNGEAWAHQRKIIAPEFFLDK-VKGMVDLMVDSAQTLLEPWEARVDKS 676 T P GE W RK+ E F K V+ + + +++ K Sbjct: 115 TFAPY---------GEYWREVRKLAVIELFSSKKVQSFRYIREEEVDFVVKKVSESALKQ 165 Query: 677 GGTVDIKIDDDIRAYSADVISRTCFGSSYVKGKKIFLKLRELQKAVSKPNVLAEMTGLRF 856 + + + +A +I R G ++ + + + R + L T F Sbjct: 166 S---PVDLSKTFFSLTASIICRVALGQNFNESGFVIDQDRIEELVTESAEALGTFTFSDF 222 Query: 857 FPTKKNRQAWGL---HKQVHRLILEI------------VKESGEDKNLLRAIL------H 973 FP R L HK+++++ E+ E ++++++ IL Sbjct: 223 FPGGLGRFVDWLFQRHKKINKVFKELDAFYQHVIDDHLKPEGRKNQDIVTLILDMIDKQE 282 Query: 974 SASSSKVGLGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVC 1153 + S K+ + + ++D ++ AG +++AVT W + L +P + ++ + Sbjct: 283 DSDSFKLNMDNLKAIVMD----VFLAGIDTSAVTMIWAMTELIRNPRVMKKAQESIRTTL 338 Query: 1154 GGRP--LDSQSLQKMKNLTMVIQETLRLYPAGAFV-SRMALQELKLGGVHIPKGVNIYIP 1324 G + + + L K++ L +++ET RL+PA FV R + +K+ G IP I + Sbjct: 339 GLKKERITEEDLGKVEYLNHILKETFRLHPALPFVVPRETMSHIKIQGYDIPPKTQIQLN 398 Query: 1325 VSTMHLDPKLWGPDAKEFNPARFS----DARPQLHSYLPFGAGARTCLGQGFATA 1477 V T+ DPK W D +EFNP RF+ D R Q LPFG+G R C G A A Sbjct: 399 VWTIGRDPKRWN-DPEEFNPERFANSSVDFRGQHFDLLPFGSGRRICPGMPMAIA 452
>Q9W130:CP9C1_DROME Cytochrome P450 9c1 - Drosophila melanogaster (Fruit fly)| Length = 522 Score = 92.8 bits (229), Expect = 4e-18 Identities = 92/413 (22%), Positives = 183/413 (44%), Gaps = 42/413 (10%) Frame = +2 Query: 368 KEHGPVFTYSMGNVVFLHVSRPDVVRDI---NLCVSLDLGKSSYLKATHEPLFGRGILKS 538 K+H +++ + ++ ++S P+++R + N + K + + +L Sbjct: 68 KQHKVYGVFNLRDPLY-YLSDPELIRQVGIKNFDTFTNHRKGITEGFNDTSVISKSLLSL 126 Query: 539 NGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRA 718 W R + P F K++ M +L+ ++ + ++D GT ++++ D Sbjct: 127 RDRRWKQMRSTLTPTFTSLKIRQMFELIHFCNVEAVDFVQRQLD--AGTSELELKDFFTR 184 Query: 719 YSADVISRTCFGSS-----------YVKGKKI-------------FLKLRELQKAVSKPN 826 Y+ DVI+ FG + G++I ++ + +L KA+ P Sbjct: 185 YTNDVIATAAFGIQVNSFKDPNNEFFSIGQRISEFTFWGGLKVMLYILMPKLMKALRVP- 243 Query: 827 VLAEMTGLRFFPTKKNRQAWGLHKQVHRLILEIVKESGEDKNLLRAILHSASSSKVGLGE 1006 + +M + +F K A K+ + +++ E + +A ++ S + Sbjct: 244 -VMDMNNVDYFK-KLVFGAMKYRKEQSIVRPDMIHLLMEAQRQFKAEQEGSAESAAQQDK 301 Query: 1007 AE---NFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEV---CGGRPL 1168 AE + ++ C + AG+E+ A ++ L ++PE Q+++ E+L V G +PL Sbjct: 302 AEFNDDDLLAQCLLFFSAGFETVATCLSFTSYELMMNPEVQEKLLAEILAVKEQLGEKPL 361 Query: 1169 DSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKLGG------VHIPKGVNIYIPVS 1330 D +L MK L V+ E+LR +P V RM + +L V++ + ++I V Sbjct: 362 DYDTLMGMKYLNCVVSESLRKWPPAFIVDRMCGSDFQLKDEEGEVVVNLREDDLVHINVG 421 Query: 1331 TMHLDPKLWGPDAKEFNPARFSDARP---QLHSYLPFGAGARTCLGQGFATAE 1480 +H DP + P+ ++F P RF + + +YLPFG G R+C+G A E Sbjct: 422 ALHHDPDNF-PEPEQFRPERFDEEHKHEIRQFTYLPFGVGQRSCIGNRLALME 473
>Q12588:CP52J_CANMA Cytochrome P450 52A10 - Candida maltosa (Yeast)| Length = 519 Score = 92.4 bits (228), Expect = 5e-18 Identities = 107/384 (27%), Positives = 162/384 (42%), Gaps = 35/384 (9%) Frame = +2 Query: 509 PLFGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTV 688 PL G+GI +G W H R ++ P+F D++ G V ++ Q L + + K+ GT Sbjct: 127 PLLGKGIFTLDGNGWKHSRAMLRPQFSRDQI-GHVKMLEPHFQLL----KKHIIKNKGTF 181 Query: 689 DIKIDDDIRAYSADVISRTCFGSSY--VKGKKIFLKLRELQKAVSKPNVLAEMTGLRFFP 862 I + ++ D + FG S +K + I E+ A K A + Sbjct: 182 -FDIQELFFRFTVDSATEFLFGESVSSLKDESIGYDQEEIDFAGRKDFAEAFNKSQVYLS 240 Query: 863 TKKNRQA--WGLHKQVHRLILEIVKESGED--KNLLRAILHSAS--SSKVGLGEAEN--- 1015 T+ Q W ++ + +IV + + K L A SS + L E Sbjct: 241 TRTLLQLLYWLVNSADFKRCNKIVHKFSDYYIKKALTATPEELEKHSSYIFLYELAKQTR 300 Query: 1016 ---FIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGRPLDSQS-- 1180 + D +I AG ++TA ++ + LG +PE ++RQE+ G LDS S Sbjct: 301 DPIVLRDQSLNILLAGRDTTAGLLSFAVFELGRNPEVWSKLRQEIGHKFG---LDSYSRV 357 Query: 1181 -------LQKMKNLTMVIQETLRLYPAGAFVSRMALQELKL---GG------VHIPKGVN 1312 L+ + L V+ ETLRLYP+ +R A + L GG + + KG Sbjct: 358 EDISFELLKLCEYLKAVLNETLRLYPSVPRNARFAAKNTTLPHGGGPDGMSPILVRKGQT 417 Query: 1313 IYIPVSTMHLDPKLWGPDAKEFNPARF--SDARPQLHSYLPFGAGARTCLGQGFATAEXX 1486 + V + D K +G DA EF P R+ + R ++LPF G R CLGQ FA E Sbjct: 418 VMYSVYALQRDEKYYGKDANEFRPERWFEPEVRKLGWAFLPFNGGPRICLGQQFALTEAS 477 Query: 1487 XXXXXXXXXF-ALRLSPLYQHSPA 1555 F L LSP + PA Sbjct: 478 YVLARLIQSFETLELSPEAAYPPA 501
>P33269:CP4D1_DROME Cytochrome P450 4d1 - Drosophila melanogaster (Fruit fly)| Length = 512 Score = 92.4 bits (228), Expect = 5e-18 Identities = 90/358 (25%), Positives = 155/358 (43%), Gaps = 33/358 (9%) Frame = +2 Query: 506 EPLFGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGT 685 EP G+L S G W +RKII P F + V++ ++ LL E K G + Sbjct: 112 EPWLKEGLLVSRGRKWHKRRKIITPAFHFKILDQFVEVFEKGSRDLLRNMEQDRLKHGES 171 Query: 686 VDIKIDDDIRAYSADVISRTCFG----------SSYVKGKKIFLKLRELQKAVSKPNVLA 835 + D I + D I T G S YV+ K + L K + Sbjct: 172 -GFSLYDWINLCTMDTICETAMGVSINAQSNADSEYVQAVKTISMV--LHKRMFNILYRF 228 Query: 836 EMTGLRFFPTKKNRQAWG-LHKQVHRLIL----EIVKE------SGEDKNL----LRAIL 970 ++T + + ++A LH+ ++I+ E+++E S +D ++ A L Sbjct: 229 DLTYMLTPLARAEKKALNVLHQFTEKIIVQRREELIREGSSQESSNDDADVGAKRKMAFL 288 Query: 971 HSASSSKVGLGEAENF-IVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLE 1147 S V N I + + F G+++T+ + + HPE Q + +E+ Sbjct: 289 DILLQSTVDERPLSNLDIREEVDTFMFEGHDTTSSALMFFFYNIATHPEAQKKCFEEIRS 348 Query: 1148 VCGG---RPLDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKLGGVHIPKGVNIY 1318 V G P+ + L ++ + + ++ETLR+YP+ + R L++ ++ G IP G NI Sbjct: 349 VVGNDKSTPVSYELLNQLHYVDLCVKETLRMYPSVPLLGRKVLEDCEINGKLIPAGTNIG 408 Query: 1319 IPVSTMHLDPKLWGPDAKEFNPARF----SDARPQLHSYLPFGAGARTCLGQGFATAE 1480 I + +L+ + F P RF + + ++Y+PF AG R C+GQ FA E Sbjct: 409 ISPLYLGRREELFS-EPNSFKPERFDVVTTAEKLNPYAYIPFSAGPRNCIGQKFAMLE 465
>P95099:CP136_MYCTU Putative cytochrome P450 136 - Mycobacterium tuberculosis| Length = 492 Score = 92.4 bits (228), Expect = 5e-18 Identities = 86/371 (23%), Positives = 161/371 (43%), Gaps = 7/371 (1%) Frame = +2 Query: 509 PLFGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDS-AQTLLEPWEARVDKSGGT 685 P F RG++ + E R+I+ F ++ G ++ M ++ + + W + Sbjct: 131 PFFHRGLMLLDFEEHMFHRRIMQEAFVRSRLAGYLEQMDRVVSRVVADDWVVNDAR---- 186 Query: 686 VDIKIDDDIRAYSADVISRTCFGSSYVKGKKIFLKLRELQKAVSKPNVLAEMTGLRFFPT 865 + ++A + D+ S G ++ K+ + ++ T + F Sbjct: 187 --FLVYPAMKALTLDIASMVFMGHEPGTDHELVTKVNKAFTITTRAGNAVIRTSVPPFTW 244 Query: 866 KKNRQAWGLHKQVHRLILEIVKE-SGEDKNLLRAILHSASSSKVGLGEAENFIVDNCKSI 1042 + +A L + ++ +E SG D LL + + +A+ IV++ + Sbjct: 245 WRGLRARELLENYFTARVKERREASGND--LLTVLCQTEDDDGNRFSDAD--IVNHMIFL 300 Query: 1043 YFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGRPLDSQSLQKMKNLTMVIQET 1222 A ++++ TA L HPEWQ R R E + G PLD +SL+++++L +V+ E+ Sbjct: 301 MMAAHDTSTSTATTMAYQLAAHPEWQQRCRDES-DRHGDGPLDIESLEQLESLDLVMNES 359 Query: 1223 LRLYPAGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARFSDA 1402 +RL + R +++ +L G ++PKG N+ H P++W D F+P RF++ Sbjct: 360 IRLVTPVQWAMRQTVRDTELLGYYLPKGTNVIAYPGMNHRLPEIW-TDPLTFDPERFTEP 418 Query: 1403 RPQ----LHSYLPFGAGARTCLGQGFATAEXXXXXXXXXXXFALRLS-PLYQHSPALKLI 1567 R + +++ PFG G C+G F E + L LS P YQ + Sbjct: 419 RNEHKRHRYAFTPFGGGVHKCIGMVFDQLEIKTILHRLLRRYRLELSRPDYQPRWDYSAM 478 Query: 1568 VEPEFGVDITL 1600 P G+ I L Sbjct: 479 PIPMDGMPIVL 489
>Q12586:CP52I_CANMA Cytochrome P450 52A9 - Candida maltosa (Yeast)| Length = 521 Score = 92.0 bits (227), Expect = 7e-18 Identities = 99/376 (26%), Positives = 157/376 (41%), Gaps = 51/376 (13%) Frame = +2 Query: 506 EPLFGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLM--------------------- 622 +PL G GI +GE W H R ++ P+F ++V G V L+ Sbjct: 128 KPLLGYGIFTLDGEGWKHSRAMLRPQFAREQV-GHVKLIEPHFQSLKKHIIKNKGQFFDI 186 Query: 623 --------VDSAQTLL--EPWEARVDKSGGTVDIKIDDDIRAYSADVISRTCFGSSYVKG 772 VDSA L E E+ D+S G D D R A+ ++ Y+ Sbjct: 187 QELFFRFTVDSATEFLFGESVESLKDESIGYDQQDFDFDGRKNFAEAFNKA---QEYLGT 243 Query: 773 KKIFLKLRELQKAVSKPNVLAEMTGLRFFPTKKNRQAWGLHKQVHR---LILEIVKESGE 943 + I L +AE+ + +K A + H + E+V+++ Sbjct: 244 RAILQLFYWLVNGADFKKSVAEVHKFTDYYVQKALDATPEELEKHSGYIFLYELVQQT-R 302 Query: 944 DKNLLRAILHSASSSKVGLGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQD 1123 D +LR D +I AG ++TA ++ L L +PE Sbjct: 303 DPKVLR---------------------DQSLNILLAGRDTTAGLLSFALFELARNPEVWS 341 Query: 1124 RVRQEVLEVCGG------RPLDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKL- 1282 R+R+E+ + G + +SL++ + L V+ E LR+YP+ R+A + L Sbjct: 342 RLREEIGDKFGLDEDATIEGISFESLKQCEYLKAVVNECLRMYPSVPRNFRIATKHTTLP 401 Query: 1283 --GG------VHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARFS--DARPQLHSYLPF 1432 GG + I KG + +++ HLDP +GPDA+ FNP R+S + + ++LPF Sbjct: 402 RGGGPDGKDPIFIKKGAVVSYGINSTHLDPMYYGPDARLFNPDRWSKPETKKLGWAFLPF 461 Query: 1433 GAGARTCLGQGFATAE 1480 G R CLGQ FA E Sbjct: 462 NGGPRICLGQQFALTE 477
>P51589:CP2J2_HUMAN Cytochrome P450 2J2 - Homo sapiens (Human)| Length = 502 Score = 92.0 bits (227), Expect = 7e-18 Identities = 94/398 (23%), Positives = 172/398 (43%), Gaps = 27/398 (6%) Frame = +2 Query: 368 KEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRGILKSNGE 547 K++G +F+ +G++ + ++ ++++ + + + G G++ S+G+ Sbjct: 73 KKYGNLFSLELGDISAVLITGLPLIKEALIHMDQNFGNRPVTPMREHIFKKNGLIMSSGQ 132 Query: 548 AWAHQRKIIAP---EFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVD--IKIDDDI 712 AW QR+ F L K K + + + + AQ L E A +++G D KI++ + Sbjct: 133 AWKEQRRFTLTALRNFGLGK-KSLEERIQEEAQHLTE---AIKEENGQPFDPHFKINNAV 188 Query: 713 RAYSADVISRTCFGSSYVKGKKIFLKLRELQKAVSKPNVLAEMTGLRFFP------TKKN 874 +++I FG + F +L +L V+ FP + Sbjct: 189 ----SNIICSITFGERFEYQDSWFQQLLKLLDEVTYLEASKTCQLYNVFPWIMKFLPGPH 244 Query: 875 RQAWGLHKQVHRLILEIVKESGEDKN------LLRAILHSASS---SKVGLGEAENFIVD 1027 + + K++ + ++ + +D N + A L S + EN I Sbjct: 245 QTLFSNWKKLKLFVSHMIDKHRKDWNPAETRDFIDAYLKEMSKHTGNPTSSFHEENLICS 304 Query: 1028 NCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCG-GRPLDSQSLQKMKNLT 1204 ++FAG E+T+ T W L+ + L+PE Q++V+ E+ V G G+ + + + M Sbjct: 305 TL-DLFFAGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQGQQPSTAARESMPYTN 363 Query: 1205 MVIQETLR---LYPAGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWG-PDAK 1372 VI E R + P V R + L G H+PKG I ++ +H DP W PD Sbjct: 364 AVIHEVQRMGNIIPLN--VPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWATPDT- 420 Query: 1373 EFNPARF--SDARPQLHSYLPFGAGARTCLGQGFATAE 1480 FNP F + + +++PF G R CLG+ A E Sbjct: 421 -FNPDHFLENGQFKKREAFMPFSIGKRACLGEQLARTE 457
>Q43068:C82A1_PEA Cytochrome P450 82A1 - Pisum sativum (Garden pea)| Length = 544 Score = 92.0 bits (227), Expect = 7e-18 Identities = 96/418 (22%), Positives = 174/418 (41%), Gaps = 55/418 (13%) Frame = +2 Query: 371 EHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRGIL--KSNG 544 ++GP+FT +G L +S ++ ++ + + A + + + G Sbjct: 67 KYGPIFTIKLGATNALVLSNWELAKECFTKNDIVVSSRPKPVAVELMSYNQAFIGWAPYG 126 Query: 545 EAWAHQRKIIAPEFFLDK-VKGMVDLMVDSAQT----LLEPWEARVDKSGGTVDIK---- 697 W RKI+ E ++ ++ + + V QT L+ W ++ G +D Sbjct: 127 AYWRQLRKIVTLEILSNRRIELLSHIRVSEVQTSIKELVNVWSNQISSQYGLLDDTKSSS 186 Query: 698 ----------IDDDIRAYSAD---------VISRTCFGSSYVKGK---KIFLK-LRELQK 808 + +++ + A V+ + CFG V+ K K FL+ +R+ + Sbjct: 187 TNDEPSTTDYVSVELKKWFAQLTLNMVLRMVVGKRCFGDVDVENKEEAKRFLENIRDFMR 246 Query: 809 AVSKPNVLAEMTGLRFFPTKKN-RQAWGLHKQVHRLILEIVKESGEDKNL---------- 955 + V + L++ + ++ K+ ++ E ++E E K L Sbjct: 247 LIGTFTVGDGVPFLKWLDLGGHEKEMKKCAKKFDVMLNEWLEEHREKKGLGSEDKVVGER 306 Query: 956 --LRAILHSASSSKVGLGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRV 1129 + A+L + + + I + G ++TA T W + LL HP +++ Sbjct: 307 DFMDAMLLVLKDKPIEGFDVDTIIKATTLELILGGSDTTAGTLTWAMCLLLKHPHVLEKL 366 Query: 1130 RQEVLEVCGG-RPLDSQSLQKMKNLTMVIQETLRLYPAGAFVS-RMALQELKLGGVHIPK 1303 ++E+ G R ++ + K+ L +I+ETLRLYP F S R ++ +GG HI K Sbjct: 367 KEELNTYIGKERCVNESDINKLVYLHAIIKETLRLYPPAPFSSPREFTEDCTIGGYHIKK 426 Query: 1304 GVNIYIPVSTMHLDPKLWGPDAKEFNPARF------SDARPQLHSYLPFGAGARTCLG 1459 G + + +H DP +W PD EF P RF D R Q LPFG+G R C G Sbjct: 427 GTRLMPNLWKIHRDPSVW-PDPLEFKPERFLSTHKDVDVRGQNFELLPFGSGRRMCAG 483
>P58049:C71BB_ARATH Cytochrome P450 71B11 - Arabidopsis thaliana (Mouse-ear cress)| Length = 496 Score = 92.0 bits (227), Expect = 7e-18 Identities = 96/412 (23%), Positives = 177/412 (42%), Gaps = 39/412 (9%) Frame = +2 Query: 359 KWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRGILKS 538 K +++GP+ G+V + S P+ V+++ + Y+ + LK Sbjct: 55 KLSEKYGPLMALRFGSVSTVVASTPETVKEVLKTFDAECCSRPYMTYPARLTYN---LKD 111 Query: 539 NG-----EAWAHQRKIIAPEFFLDK------------VKGMVDLMVDSAQTLLEPWEARV 667 G + W RK+ E + K V +VD + +A +L +P Sbjct: 112 IGFCPYTKYWREVRKMTVVELYTAKRVQSFQHTRKEEVASLVDFITQAA-SLEKP----- 165 Query: 668 DKSGGTVDIKIDDDIRAYSADVISRTCFGSSYVKGKKIFLKLRELQKAVSKPNVLAEMTG 847 + ++ + S VI R FG + +KG K+ E+ + + V+ Sbjct: 166 --------VNLNTKLMKLSGSVICRVVFGIN-LKGSKLENLYEEVIQGTME--VVGSFAA 214 Query: 848 LRFFPT--KKNRQAWGLHKQVHRLILEI-------VKESGEDKNL---LRAILHSASSSK 991 +FP + + GLH + ++ + +K ED+++ + +L + Sbjct: 215 ADYFPIIGRIIDRITGLHSKCEKIFKAMDAFFDQSIKHHLEDESIKDDIIDLLLKMERGE 274 Query: 992 VGLGEAENFIVDNCKSIYF----AGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGG 1159 + LGE + DN K I F AG +++A W + L +P + + EV EV Sbjct: 275 IELGEFQ-LTRDNTKGILFNILNAGIDTSAQVMTWVMTYLISNPRVMKKAQAEVREVIKN 333 Query: 1160 RP-LDSQSLQKMKNLTMVIQETLRLYP-AGAFVSRMALQELKLGGVHIPKGVNIYIPVST 1333 + + + +++++ L MV++ET R+ P + R A +++K+GG IPK I++ + Sbjct: 334 KDDIIEEDIERLEYLKMVVKETFRVLPLVPLLIPREASKDVKIGGYDIPKKTWIHVNIWA 393 Query: 1334 MHLDPKLWGPDAKEFNPARFSDARPQL----HSYLPFGAGARTCLGQGFATA 1477 +H +P +W D + F P RF D + +LPFG+G R C G G A Sbjct: 394 IHRNPNVW-KDPEAFIPERFMDNQIDYKGLNFEFLPFGSGRRMCPGIGMGMA 444
>Q9VB31:C6A18_DROME Probable cytochrome P450 6a18 - Drosophila melanogaster (Fruit fly)| Length = 507 Score = 92.0 bits (227), Expect = 7e-18 Identities = 117/480 (24%), Positives = 201/480 (41%), Gaps = 38/480 (7%) Frame = +2 Query: 143 LALYLYYTVWVVPQRLLAGFRRQGIGGPRPSFPYGNMADXXXXXXXXXXXXXXXXXXXIV 322 +A+ L V + R L F+R+GI +P GNM V Sbjct: 10 VAVALLAIVTYILHRKLTYFKRRGIPYDKPHPLRGNMEGYKKTRT--------------V 55 Query: 323 HDYRPAVLPFYEKWRKEHGP-----VFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSS 487 H+ +Y K+R P +F V+ L +++ ++++ + K Sbjct: 56 HEIHQE---YYNKYRNSKAPFVGFYLFQKPAAFVIDLELAKQILIKNFSNFTD----KGI 108 Query: 488 YLKATHEPLFGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARV 667 Y +P+ + +G W R ++ F K+K M +V A+ + +V Sbjct: 109 YYNEKDDPMSAH-LFNLDGPQWRLLRSKLSSTFTSGKMKFMYPTVVSVAEEFMAVMHEKV 167 Query: 668 DKSGGTVDIKIDDDIRAYSADVISRTCFG---SSYVKGKKIFLKLRELQKAVSKPNVLAE 838 ++ +D++ D + ++ DVI FG +S K FL S+ L Sbjct: 168 SENS-ILDVR--DLVARFTVDVIGTCAFGIKCNSLRDEKAEFLHFGRRALLDSRHGNL-- 222 Query: 839 MTGL-RFFPTKKNRQAWGLHK---QVHRLILEIVKES---GEDKNLLRAILHSASSSKVG 997 ++GL R +P R GL + Q+ IVKE+ E +N+ R + +G Sbjct: 223 VSGLMRSYPNLARRL--GLCRNTAQIQEFYQRIVKETVTLREKENIKR---NDFMDMLIG 277 Query: 998 LGEAENFIVDNCKSI---------------YFAGYESTAVTAAWCLMLLGLHPEWQDRVR 1132 L +N ++N + + + AG+++++ T + L L +P QD+VR Sbjct: 278 LKNQKNMTLENGEVVKGLTMDEIVAQAFVFFIAGFDTSSSTMGFALYELAKNPSIQDKVR 337 Query: 1133 QEVLEVC--GGRPLDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKLGG---VHI 1297 E+ +V + + ++ +K L VI ETLR Y V R+A + + G I Sbjct: 338 AELGQVLEQHDQKFTYECIKDLKYLDQVINETLRHYTIVPNVDRVAAKRFVVPGNPKFVI 397 Query: 1298 PKGVNIYIPVSTMHLDPKLWGPDAKEFNPARFS---DARPQLHSYLPFGAGARTCLGQGF 1468 G ++ IP S +H DP ++ P+ EF P RFS A+ ++LPFG G R C+G F Sbjct: 398 EAGQSVIIPSSAIHHDPSIY-PEPNEFRPERFSPEESAKRPSVAWLPFGEGPRNCIGLRF 456
>Q9SAB6:C71AI_ARATH Cytochrome P450 71A18 - Arabidopsis thaliana (Mouse-ear cress)| Length = 497 Score = 91.7 bits (226), Expect = 9e-18 Identities = 88/387 (22%), Positives = 154/387 (39%), Gaps = 21/387 (5%) Frame = +2 Query: 374 HGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRG--ILKSNGE 547 +GP+ G V L VS + +I L KA H + G + GE Sbjct: 64 YGPLMLLHFGRVPILVVSSSEAAHEILKTHDLKFANRPKSKAVHGLMNGGRDVVFGPYGE 123 Query: 548 AWAHQRKIIAPEFFLDK-VKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAYS 724 W + + +K V + + ++E E S + + + Sbjct: 124 YWRQMKSVCILNLLTNKMVASFEKVREEEVNAMMEKLEKASCSSSAE---NLSELFVTLT 180 Query: 725 ADVISRTCFGSSYVKG----------KKIFLKLRELQKAVSKPNVLAEMTGLRFFPTKKN 874 +DV SR G Y + ++I LRE P LA + + F +K Sbjct: 181 SDVTSRVSLGKKYWEDETAGGLKKRVRQIMELLREFPIGDYVP-ALAWIDRINGFNSKIV 239 Query: 875 RQAWGLHKQVHRLILEIVKESGEDK-NLLRAILHSASSSKVGLGEAENFIVDNCKSIYFA 1051 + + +++ E + E+GE K + + +L G N I ++ Sbjct: 240 EVSRAYSDLMEKVVQEHL-EAGEHKADFVNILLSIEKEKNNGFKVQRNDIKFMILDMFIG 298 Query: 1052 GYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCG--GRPLDSQSLQKMKNLTMVIQETL 1225 G +++ W + L +PE +++ E+ G + + ++ M+ L VI+E Sbjct: 299 GISTSSTLLEWIMTELIRNPECMKKLQNEIRSTIRPHGSYIKEKEVENMRYLKAVIKEVF 358 Query: 1226 RLYPAGAFV-SRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARFSDA 1402 R++P + R+ +++K+ G I G + I ++H DP +WGPDA+EF P R D+ Sbjct: 359 RVHPPLPLILPRLLTEDVKVKGYDIAAGTEVLINAWSIHRDPAIWGPDAEEFKPERHLDS 418 Query: 1403 RPQLH----SYLPFGAGARTCLGQGFA 1471 H Y+PFG+G R C G A Sbjct: 419 TLDYHGQDLKYIPFGSGRRICPGINLA 445
>Q9VMS9:C4AC1_DROME Probable cytochrome P450 4ac1 - Drosophila melanogaster (Fruit fly)| Length = 509 Score = 91.7 bits (226), Expect = 9e-18 Identities = 82/349 (23%), Positives = 151/349 (43%), Gaps = 25/349 (7%) Frame = +2 Query: 509 PLFGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTV 688 P G G+L S W +RK + P F + ++ + + + + L E +D Sbjct: 125 PFLGDGLLISTDHKWHSRRKALTPAFHFNVLQSFLGIFKEECKKFLNVLEKNLD-----A 179 Query: 689 DIKIDDDIRAYSADVISRTCFG------SSYVKGKKIFLKLRE-LQKAVSKPNVLAEMTG 847 +++++ I ++ + I T G S + +K + E L + V P + Sbjct: 180 ELELNQVIPPFTLNNICETALGVKLDDMSEGNEYRKAIHAIEEVLIQRVCNPLMYYNWYF 239 Query: 848 LRFFPTKKNRQAWGLHKQVHRLILEIVKESGEDKNLLR----------AILHSASSSKVG 997 + +K+ Q + I+E ++ + K L A+L + +++ Sbjct: 240 FVYGDYRKHLQNLRIVHDFSSRIIERKRQQFQQKQLGEVDEFGRKQRYAMLDTLLAAEAD 299 Query: 998 LGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGRPLDSQ 1177 I D + F GY++T+ + L++L LH + Q + +EV + P DS Sbjct: 300 GQIDHQGICDEVNTFMFEGYDTTSTCLIFTLLMLALHEDVQKKCYEEVENL----PEDSD 355 Query: 1178 SLQ-----KMKNLTMVIQETLRLYPAGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHL 1342 + K+ L VI+E+LR++P+ F+ R ++E + G+ +PK I I + + Sbjct: 356 DISMFQFNKLVYLECVIKESLRMFPSVPFIGRQCVEETVVNGMVMPKDTQISIHIYDIMR 415 Query: 1343 DPKLWGPDAKEFNPARF---SDARPQLHSYLPFGAGARTCLGQGFATAE 1480 DP+ + P F P RF + +Y+PF AG R C+GQ FA E Sbjct: 416 DPRHF-PKPDLFQPDRFLPENTVNRHPFAYVPFSAGQRNCIGQKFAILE 463
>Q9FH76:ABAH3_ARATH Abscisic acid 8'-hydroxylase 3 - Arabidopsis thaliana (Mouse-ear| cress) Length = 463 Score = 91.7 bits (226), Expect = 9e-18 Identities = 86/382 (22%), Positives = 167/382 (43%), Gaps = 5/382 (1%) Frame = +2 Query: 350 FYEKWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRGI 529 F+ ++ +G VF + + +S P+ + + L L K ++ + L + I Sbjct: 60 FFAAKQRRYGSVFKTHVLGCPCVMISSPEAAKFV-LVTKSHLFKPTFPASKERMLGKQAI 118 Query: 530 LKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDD 709 G+ + RK++ F D ++ MV + AQ L W+ + + Sbjct: 119 FFHQGDYHSKLRKLVLRAFMPDAIRNMVPHIESIAQESLNSWDG--------TQLNTYQE 170 Query: 710 IRAYSADVISRTCFGSSYVKGKKIFLKLRE-LQKAVSKPNVLAEMTGLRFFPTKKNRQAW 886 ++ Y+ +V + G V ++ + L+K + + + G F K R Sbjct: 171 MKTYTFNVALISILGKDEVYYREDLKRCYYILEKGYNSMPI--NLPGTLFHKAMKAR--- 225 Query: 887 GLHKQVHRLILEIVKESGEDKNLLRAILHSASSSKVGLGEAENFIVDNCKSIYFAGYEST 1066 K++ +++ I+ + ++ + +L S K GL + + I DN + FA ++T Sbjct: 226 ---KELAQILANILSKRRQNPSSHTDLLGSFMEDKAGLTDEQ--IADNIIGVIFAARDTT 280 Query: 1067 AVTAAWCLMLLGLHPEWQDRVRQEVLEVCG----GRPLDSQSLQKMKNLTMVIQETLRLY 1234 A W L L +P + V +E + + G L + +KM VIQETLR Sbjct: 281 ASVLTWILKYLADNPTVLEAVTEEQMAIRKDKKEGESLTWEDTKKMPLTYRVIQETLRAA 340 Query: 1235 PAGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARFSDARPQL 1414 +F R A+++++ G IPKG + +H + ++ D +F+P+RF + P+ Sbjct: 341 TILSFTFREAVEDVEYEGYLIPKGWKVLPLFRNIHHNADIFS-DPGKFDPSRF-EVAPKP 398 Query: 1415 HSYLPFGAGARTCLGQGFATAE 1480 ++++PFG+G +C G A E Sbjct: 399 NTFMPFGSGIHSCPGNELAKLE 420
>Q96423:TCMO_GLYEC Trans-cinnamate 4-monooxygenase - Glycyrrhiza echinata (Licorice)| Length = 505 Score = 91.3 bits (225), Expect = 1e-17 Identities = 104/394 (26%), Positives = 168/394 (42%), Gaps = 30/394 (7%) Frame = +2 Query: 368 KEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRG---ILKS 538 K G +F MG + VS P++ +++ ++ G S + G+G + Sbjct: 63 KRFGDIFLLRMGQRNLVVVSSPELAKEVLHTQGVEFG-SRTRNVVFDIFTGKGQDMVFTV 121 Query: 539 NGEAWAHQRKIIAPEFFLDKVKGMVDLMVDS-AQTLLEPWEARVDKSGGTVDIKIDDDIR 715 GE W R+I+ FF +KV +S A ++++ D + G + ++ + Sbjct: 122 YGEHWRKMRRIMTVPFFTNKVVQQYRFGWESEAASVVDDVRRNPDAAAGGIVLRRRLQLM 181 Query: 716 AYSADVISRTCFGSSYVKGKK-IFLKLRELQKAVSKPNVLAEMTGLRFFPTKKN--RQAW 886 Y+ + R F + + +F+KL+ L S+ E F P + + Sbjct: 182 MYNN--MYRIMFDRRFESEEDPLFVKLKALNGERSRLAQSFEYNYGDFIPILRPFLKGYL 239 Query: 887 GLHKQVHRLILEIVKE-------------SGEDKNLLRAILHSASSSKVGLGEAEN--FI 1021 + K+V L++ K+ S ++ L AI H + K G +N +I Sbjct: 240 KICKEVKERRLKLFKDYFVDERMKLESTKSTSNEGLKCAIDHILDAQKKGEINEDNVLYI 299 Query: 1022 VDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCG-GRPLDSQSLQKMKN 1198 V+N I A E+T + W + L HPE Q +VR E+ V G G + +QK+ Sbjct: 300 VEN---INVAAIETTLWSIEWGIAELVNHPEIQKKVRDEIDRVLGPGHQVTEPDMQKLPY 356 Query: 1199 LTMVIQETLRLYPA-GAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWGPDAKE 1375 L VI+ETLRL A V M L + KLGG IP I + + +P W +E Sbjct: 357 LQAVIKETLRLRMAIPLLVPHMNLHDAKLGGYDIPAESKILVNAWWLANNPANW-KRPEE 415 Query: 1376 FNPARFSDARPQLHS------YLPFGAGARTCLG 1459 F P RF + + + YLPFG G R+C G Sbjct: 416 FRPERFLEEESHVEANGNDFRYLPFGVGRRSCPG 449
>O73853:CP17A_ICTPU Cytochrome P450 17A1 - Ictalurus punctatus (Channel catfish)| Length = 514 Score = 91.3 bits (225), Expect = 1e-17 Identities = 99/442 (22%), Positives = 193/442 (43%), Gaps = 32/442 (7%) Frame = +2 Query: 350 FYEKWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVS-LDLGKSSYLKATHEPLFGRG 526 F+++ +K++G +++ MG+ + V+ +++ L + G+ + G+ Sbjct: 57 FFQQLQKKYGDIYSLDMGSNRVIIVNNHHHAKEVLLRKGKIFAGRPRTVTTDILTRDGKD 116 Query: 527 ILKSNGEA-WAHQRKII--APEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIK 697 I + A W RKI+ A F + + ++ A ++ E + D+ Sbjct: 117 IAFGDYSATWKFHRKIVHGALCMFGEGTASIEKIICREASSMCE---ILTNLQSSAADLA 173 Query: 698 IDDDIRAYSADVISRTCFGSSYVKGKKIFLKLRELQKA----VSKPNVLAEMTGLRFFPT 865 ++ +V+ CF SSY +G F + + + V+K +++ L+ FP Sbjct: 174 --PELTRAVTNVVCTLCFSSSYKRGDPEFEAMLKYSQGIVDTVAKDSLVDIFPWLQLFPN 231 Query: 866 KKNRQAWGLHKQVHRLILEIVKESGED------KNLLRAILHSASSSKVG------LGEA 1009 + R +L+ + +E D ++L A+L + +SS+ +G Sbjct: 232 EDLRILRRCVSIRDKLLQKKYEEHKADFSDNIQRDLFDALLRAKNSSENNNTSTQDVGLT 291 Query: 1010 ENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGRPLDSQSLQK 1189 ++ ++ I+ AG E+T W ++ L HP+ Q ++++E L+ GR Q + Sbjct: 292 DDHLLMTVGDIFGAGVETTTTVLKWSILYLIHHPQVQRKIQEE-LDAKIGRDRHPQVNDR 350 Query: 1190 --MKNLTMVIQETLRLYPAGAF-VSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWG 1360 + L I+E LR+ P + +AL + +G + KG + + + ++H D K W Sbjct: 351 GNLPYLEATIREVLRIRPVSPLLIPHVALSDANIGEYTVQKGTRVIVNLWSLHHDEKEW- 409 Query: 1361 PDAKEFNPARFSDAR------PQLHSYLPFGAGARTCLGQGFATAEXXXXXXXXXXXFAL 1522 + + FNP RF + P L SYLPFGAG R CLG+ A E F L Sbjct: 410 KNPELFNPERFLNEEGNSLCCPSL-SYLPFGAGVRVCLGEALAKLELFLFLSWILQRFTL 468 Query: 1523 RL---SPLYQHSPALKLIVEPE 1579 + PL + +++++P+ Sbjct: 469 EVPGGQPLPELQGKFRVVLQPQ 490
>P15393:C11B1_RAT Cytochrome P450 11B1, mitochondrial precursor - Rattus norvegicus| (Rat) Length = 499 Score = 91.3 bits (225), Expect = 1e-17 Identities = 98/394 (24%), Positives = 172/394 (43%), Gaps = 23/394 (5%) Frame = +2 Query: 368 KEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLK--ATHEPLFG--RGILK 535 +E GP+F +S G + V P+ ++ S+ L L+ H L G RG+ Sbjct: 73 QELGPIFRHSAGGAQIVSVMLPEDAEKLHQVESI-LPHRMPLEPWVAHRELRGLRRGVFL 131 Query: 536 SNGEAWAHQRKIIAPEFFLDK-VKGMVDLMVDSAQTLLEPWEARV-DKSGGTVDIKIDDD 709 NG W R + P K ++ V + A+ +E + R+ + G++ I I + Sbjct: 132 LNGADWRFNRLQLNPNMLSPKAIQSFVPFVDVVARDFVENLKKRMLENVHGSMSINIQSN 191 Query: 710 IRAYSADVISRTCFGSSYVKGKKIFLKLRELQ-KAVSKPNVLAEM----TGLRFFPTKKN 874 + Y+ + + G+++ L +L+ ++V+ + L M T L F P Sbjct: 192 MFNYTMEA------SHFVISGERLGLTGHDLKPESVTFTHALHSMFKSTTQLMFLPKSLT 245 Query: 875 R----QAWGLHKQVHRLILEIVKESGEDKNLLRAILHSASSSKVGLGE-------AENFI 1021 R + W H +I E V + KN+ R + S + E + + I Sbjct: 246 RWTSTRVWKEHFDSWDIISEYVTKC--IKNVYRELAEGRQQSWSVISEMVAQSTLSMDAI 303 Query: 1022 VDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGRPLDSQ-SLQKMKN 1198 N + ++TA++ L L +P+ Q +RQE L + Q ++ + Sbjct: 304 HANSMELIAGSVDTTAISLVMTLFELARNPDVQQALRQESLAAEASIVANPQKAMSDLPL 363 Query: 1199 LTMVIQETLRLYPAGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEF 1378 L ++ETLRLYP G+FV R+ +L L H+P G + I + +M +P ++ P + + Sbjct: 364 LRAALKETLRLYPVGSFVERIVHSDLVLQNYHVPAGTFVIIYLYSMGRNPAVF-PRPERY 422 Query: 1379 NPARFSDARPQLHSYLPFGAGARTCLGQGFATAE 1480 P R+ + R + +L FG G R CLG+ A E Sbjct: 423 MPQRWLE-RKRSFQHLAFGFGVRQCLGRRLAEVE 455
>P51590:CP2J3_RAT Cytochrome P450 2J3 - Rattus norvegicus (Rat)| Length = 502 Score = 90.9 bits (224), Expect = 2e-17 Identities = 106/443 (23%), Positives = 199/443 (44%), Gaps = 25/443 (5%) Frame = +2 Query: 356 EKWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLD-LGKSSYLKATHEPLFGR-GI 529 +++ K++G V + N+ + V+ ++++I + + L + L H LF + G+ Sbjct: 69 QQFVKKYGNVLSLDFANIPSVVVTGMPLIKEIFTQMEHNFLNRPVTLLRKH--LFNKNGL 126 Query: 530 LKSNGEAWAHQRK---IIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKI 700 + S+G+ W QR+ + F L K K + + + A L+E A D+ G D Sbjct: 127 IFSSGQTWKEQRRFALMTLRNFGLGK-KSLEQRIQEEAYHLVE---AIKDEGGLPFDPHF 182 Query: 701 DDDIRAYSADVISRTCFGSSYVKGKKIFLK-LRELQKAVS-KPNVLAEMTG-----LRFF 859 + I +++I FG + F + LR L +A+ + +++ ++ L++ Sbjct: 183 N--INKAVSNIICSVTFGERFEYHDSQFQEMLRLLDEAMCLESSMMCQLYNIFPRILQYL 240 Query: 860 PTKKNRQAWGLHKQVHRLILEIVK------ESGEDKNLLRAILHSASS--SKVGLGEAEN 1015 P ++ + +++ I +I+K + E ++ + A L + K E Sbjct: 241 PGS-HQTLFSNWRKLKLFISDIIKNHRRDWDPDEPRDFIDAFLKEMAKYPDKTTTSFNEE 299 Query: 1016 FIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCG-GRPLDSQSLQKM 1192 ++ + ++FAG E+T+ T W L+ + L+PE Q++++ E+ V G GR + M Sbjct: 300 NLICSTLDLFFAGTETTSTTLRWALLCMALYPEVQEKMQAEIDRVIGQGRQPNLADRDSM 359 Query: 1193 KNLTMVIQETLRLYPAGAF-VSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWG-PD 1366 VI E R+ F V R + L G ++PKG I ++ +H DPK W PD Sbjct: 360 PYTNAVIHEVQRIGNIIPFNVPREVAVDTYLAGFNLPKGTMILTNLTALHRDPKEWATPD 419 Query: 1367 AKEFNPARF--SDARPQLHSYLPFGAGARTCLGQGFATAEXXXXXXXXXXXFALRLSPLY 1540 FNP F + + S+LPF G R CLG+ A +E F L + Sbjct: 420 T--FNPEHFLENGQFKKRESFLPFSMGKRACLGEQLARSE--------LFIFITSLIQKF 469 Query: 1541 QHSPALKLIVEPEFGVDITLTKV 1609 P + + +F + +T++ V Sbjct: 470 TFKPPVNEKLSLQFRMSVTISPV 492
>Q95328:CP17A_HORSE Cytochrome P450 17A1 - Equus caballus (Horse)| Length = 508 Score = 90.9 bits (224), Expect = 2e-17 Identities = 99/405 (24%), Positives = 175/405 (43%), Gaps = 31/405 (7%) Frame = +2 Query: 359 KWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFG--RGI- 529 K +K++GP+++ MG + V + +++ + + + AT L +G+ Sbjct: 55 KLQKKYGPIYSLRMGTKTTVMVGHYQLAKEVLIKKGKEFSGRPQV-ATLNILSDNQKGVA 113 Query: 530 LKSNGEAWAHQRKIIAPEFFLDKVKGM-VDLMVDSAQTLLEPWEARVDKSGGTVDIKIDD 706 +G W RK++ F L K ++ ++ +LL + ++G T+D+ Sbjct: 114 FADHGAPWQLHRKLVRAAFALFKDGNQKLEKIICHETSLL--CDLLATQNGQTIDLS--S 169 Query: 707 DIRAYSADVISRTCFGSSYVKGKKIFLKLRELQKAV----SKPNVLAEMTGLRFFPTK-- 868 + +VI CF SSY+KG ++ K + K NV+ L+ FP K Sbjct: 170 PLFLAVTNVICWICFNSSYMKGDPALETMQNYHKGILETLEKDNVVDIFPALKIFPNKSL 229 Query: 869 -KNRQAWGLHKQVHRLILEIVKESGEDKN------LLRAILHSASSSKVGLGE-----AE 1012 K R + ++ I E KE+ + LL ++ ++ G + ++ Sbjct: 230 EKMRHCVNIRNELLSKIFEKHKENFNSDSITSMLDLLIQAKKNSDNNNTGPDQDSKLLSD 289 Query: 1013 NFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCG-GRPLDSQSLQK 1189 I+ I+ AG E+T W + L P+ + ++++E+ + G R + Sbjct: 290 KHILATIGDIFGAGVETTTSVVKWIVAFLLHDPQLKKKIQEEIDQNVGFSRTPTLSDRNR 349 Query: 1190 MKNLTMVIQETLRLYP-AGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWG-P 1363 + L I+E LR+ P A + AL + +G + G N+ I + +H + K W P Sbjct: 350 LLLLEATIREVLRIRPVAPMLIPHKALVDSSIGEFAVDDGTNVIINLWALHHNEKEWHQP 409 Query: 1364 DAKEFNPARFSDAR------PQLHSYLPFGAGARTCLGQGFATAE 1480 D F P RF D P L SYLPFGAG R+C+G+ A E Sbjct: 410 D--RFMPERFLDPTGSQLISPSL-SYLPFGAGPRSCIGELLARQE 451
>P58051:C71BE_ARATH Cytochrome P450 71B14 - Arabidopsis thaliana (Mouse-ear cress)| Length = 496 Score = 90.9 bits (224), Expect = 2e-17 Identities = 95/399 (23%), Positives = 174/399 (43%), Gaps = 26/399 (6%) Frame = +2 Query: 359 KWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRGILKS 538 K +++G + + GNV + S P+ V+D+ + Y+ + L Sbjct: 55 KLSEKYGSLMSLKFGNVSAVVASTPETVKDVLKTFDAECCSRPYMTYPARVTYNFNDLAF 114 Query: 539 N--GEAWAHQRKIIAPEFFLDK-VKGMVDLMVDSAQTLLE--PWEARVDKSGGTVDIKID 703 + + W RK+ E + K VK ++ + + ++ A ++K TV++K Sbjct: 115 SPYSKYWREVRKMTVIELYTAKRVKSFQNVRQEEVASFVDFIKQHASLEK---TVNMK-- 169 Query: 704 DDIRAYSADVISRTCFGSSYVKGKKIFLKLRELQKAVSKPNVLAEMTGLRFFPT--KKNR 877 + S VI + FG S ++ K+ E+ + + V+ +FP + Sbjct: 170 QKLVKLSGSVICKVGFGIS-LEWSKLANTYEEVIQGTME--VVGRFAAADYFPIIGRIID 226 Query: 878 QAWGLHKQVHRLILEI-------VKESGEDKNL---LRAILHSASSSKVGLGEAE---NF 1018 + GLH + ++ E+ +K ED N+ + +L + GLGE + N Sbjct: 227 RITGLHSKCEKVFKEMDSFFDQSIKHHLEDTNIKDDIIGLLLKMEKGETGLGEFQLTRNH 286 Query: 1019 IVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGRP-LDSQSLQKMK 1195 ++ AG +++ T W + L +P + + EV EV + + + +++++ Sbjct: 287 TKGILLNVLIAGVDTSGHTVTWVMTHLIKNPRVMKKAQAEVREVIKNKDDITEEDIERLE 346 Query: 1196 NLTMVIQETLRLYP-AGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWGPDAK 1372 L MVI+ETLR+ P + R A + +K+GG IPK IY+ + + +P +W D + Sbjct: 347 YLKMVIKETLRINPLVPLLIPREASKYIKIGGYDIPKKTWIYVNIWAVQRNPNVW-KDPE 405 Query: 1373 EFNPARFS----DARPQLHSYLPFGAGARTCLGQGFATA 1477 F P RF D + LPFG+G R C G G A Sbjct: 406 VFIPERFMHSEIDYKGVDFELLPFGSGRRMCPGMGLGMA 444
>O65785:C71B3_ARATH Cytochrome P450 71B3 - Arabidopsis thaliana (Mouse-ear cress)| Length = 501 Score = 90.9 bits (224), Expect = 2e-17 Identities = 96/410 (23%), Positives = 179/410 (43%), Gaps = 40/410 (9%) Frame = +2 Query: 368 KEHGPVFTYSMGNVVFLHVSRPDV------VRDINLCVSLDLGKSSYLKATHEPLFGRGI 529 K+HGPV +G + + +S + V D+ C SS + + Sbjct: 58 KKHGPVLLLRLGFIDMVVISSKEAAEEVLKVHDLECCTRPKTNASSKFSRDGKDI----A 113 Query: 530 LKSNGEAWAHQRKIIAPEFF-LDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDD 706 GE RK+ FF KV+ + + +++ + K TVD+ Sbjct: 114 FAPYGEVSRELRKLSLINFFSTQKVRSFRYIREEENDLMVKKLKESAKKKN-TVDLS--Q 170 Query: 707 DIRAYSADVISRTCFG-----SSYVKGKKIFLKLRELQKAVSKPNVLAEMTGLRFFPTKK 871 + +I R FG + +V +KI + E+QK S + G+ +F Sbjct: 171 TLFYLVGSIIFRATFGQRLDQNKHVNKEKIEELMFEVQKVGSLSSSDIFPAGVGWFMDFV 230 Query: 872 NRQAWGLHKQVHRLILEIVK----------ESGEDK------NLLRAILHSASSSKVGLG 1003 + G HK +H++ +E+ ++ EDK +++ +IL + + Sbjct: 231 S----GRHKTLHKVFVEVDTLLNHVIDGHLKNPEDKTNQDRPDIIDSILETIYKQEQD-- 284 Query: 1004 EAENFIVDNCK----SIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGRP-- 1165 E+ +D+ K +IY AG +++A+T W + L +P + ++E+ G + Sbjct: 285 ESFKLTIDHLKGIIQNIYLAGVDTSAITMIWAMAELVKNPRVMKKAQEEIRTCIGIKQKE 344 Query: 1166 -LDSQSLQKMKNLTMVIQETLRLY-PAGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMH 1339 ++ + + K++ L +VI+ETLRL+ PA + R + ++K+ G IP+ + + ++ Sbjct: 345 RIEEEDVDKLQYLKLVIKETLRLHPPAPLLLPRETMADIKIQGYDIPRKTILLVNAWSIG 404 Query: 1340 LDPKLWGPDAKEFNPARFSDA----RPQLHSYLPFGAGARTCLGQGFATA 1477 +P+LW + +EFNP RF D + LPFG+G + C G F A Sbjct: 405 RNPELW-ENPEEFNPERFIDCPMDYKGNSFEMLPFGSGRKICPGIAFGIA 453
>Q9T0K2:C71AK_ARATH Cytochrome P450 71A20 - Arabidopsis thaliana (Mouse-ear cress)| Length = 495 Score = 90.9 bits (224), Expect = 2e-17 Identities = 95/393 (24%), Positives = 159/393 (40%), Gaps = 25/393 (6%) Frame = +2 Query: 374 HGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFG-RGI-LKSNGE 547 +GP+ G L VS DV D+ L K + L G R + GE Sbjct: 61 YGPLMLLHFGRTPVLIVSSADVAHDVMKTHDLVCANRPKTKVVDKILSGGRDVAFAPYGE 120 Query: 548 AWAHQRKIIAPEFFLDK-VKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAYS 724 W + I +K V+ + + + ++E E + S + + + + Sbjct: 121 YWRQMKSICIQNLLNNKMVRSYEKIREEEIKRMIEKLE-KASCSSSPSPVNLSQILMTLT 179 Query: 725 ADVISRTCFGSSYVKGKKIFLKLRELQKAVSKPNVLAEMTGLRFFPTKK--------NRQ 880 D+I R G Y GKK + + + + + +L E + P+ + + Sbjct: 180 NDIICRVALGRKY-SGKKDGIDVENIVRTFAA--LLGEFPVGEYIPSLSWIDRIRGLDHK 236 Query: 881 AWGLHKQVHRLILEIVKESGEDKNLLRAILH----SASSSKVGLGEAENFIVDNCK-SIY 1045 + K+ + +VKE E R+ L + S K G E E + ++ Sbjct: 237 MEVVDKRFDEFLERVVKEHEEADKETRSDLVDKLLTIQSDKTGQFELEKSALKLIIWDMF 296 Query: 1046 FAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGRPLD----SQSLQKMKNLTMVI 1213 AG +T W + L +P+ ++++E+ P D + +KM L VI Sbjct: 297 LAGTATTLSFLEWAMTELMRNPKVMKKLQEEIRS---SSPQDLFVTEKEAEKMNYLQAVI 353 Query: 1214 QETLRLYP-AGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPAR 1390 +E LRL P A V R+ +++KL G +IP G + + + D WG DA+EF P R Sbjct: 354 KEALRLRPPAPLLVPRVLSEDVKLKGYNIPAGTQVIVNAWAIQRDTTTWGTDAEEFKPER 413 Query: 1391 FSDA----RPQLHSYLPFGAGARTCLGQGFATA 1477 D + Q ++PFG+G R C G GF +A Sbjct: 414 HLDTNLDFQGQDFKFIPFGSGKRICPGIGFTSA 446
>Q6V0L0:CP26C_HUMAN Cytochrome P450 26C1 - Homo sapiens (Human)| Length = 522 Score = 90.5 bits (223), Expect = 2e-17 Identities = 104/409 (25%), Positives = 183/409 (44%), Gaps = 33/409 (8%) Frame = +2 Query: 350 FYEKWRKEHGPVF-TYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRG 526 F+ R+ +G VF T+ +G V + VS + VR I L L +S + ++ H L Sbjct: 72 FHSSRRERYGTVFKTHLLGRPV-IRVSGAENVRTI-LLGEHRLVRSQWPQSAHILLGSHT 129 Query: 527 ILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDD 706 +L + GE +RK++A F ++ V + + + + W A +GG V + D Sbjct: 130 LLGAVGEPHRRRRKVLARVFSRAALERYVPRLQGALRHEVRSWCA----AGGPVSVY--D 183 Query: 707 DIRAYSADVISRTCFGSSYVKGKKIFLKLRELQKAVSKPNVLAEMTGLRFFPTKKNRQAW 886 +A + + +R G + + L R ++ V N+ + + F +K +A Sbjct: 184 ASKALTFRMAARILLGLRLDEAQCATLA-RTFEQLVE--NLFSLPLDVPFSGLRKGIRAR 240 Query: 887 G-LHKQVHRLILEIVKE--SGEDKNLLRAILHSASSSKVGLGEAENFIVDNCKSIYFAGY 1057 LH+ + I E + E + E + L I+HSA ++G + + ++ + FA + Sbjct: 241 DQLHRHLEGAISEKLHEDKAAEPGDALDLIIHSAR--ELGHEPSMQELKESAVELLFAAF 298 Query: 1058 ESTAVTAAWCLMLLGLHPEWQDRVRQEVL-----EVCGGRP------------------L 1168 +TA + ++LL HP ++R+E++ CG P L Sbjct: 299 FTTASASTSLVLLLLQHPAAIAKIREELVAQGLGRACGCAPGAAGGSEGPPPDCGCEPDL 358 Query: 1169 DSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDP 1348 +L +++ + V++E LRL P + R AL+ +L G IPKG ++ + H Sbjct: 359 SLAALGRLRYVDCVVKEVLRLLPPVSGGYRTALRTFELDGYQIPKGWSVMYSIRDTHETA 418 Query: 1349 KLWGPDAKEFNPARFSDARPQLHS------YLPFGAGARTCLGQGFATA 1477 ++ + F+P RF AR Y+PFG GAR+CLGQ A A Sbjct: 419 AVYRSPPEGFDPERFGAAREDSRGASSRFHYIPFGGGARSCLGQELAQA 467
>Q27593:CP6A8_DROME Cytochrome P450 6a8 - Drosophila melanogaster (Fruit fly)| Length = 506 Score = 90.1 bits (222), Expect = 3e-17 Identities = 117/480 (24%), Positives = 195/480 (40%), Gaps = 33/480 (6%) Frame = +2 Query: 128 VGACSLALYLYYTVWVVPQRLLAGFRRQGIGGPRPSFPYGNMADXXXXXXXXXXXXXXXX 307 V LA+ YY R L F+R+GI P GNM + Sbjct: 10 VAVALLAILTYYI-----HRKLTYFKRRGIPFVAPHLIRGNMEELQKTKNIHE------- 57 Query: 308 XXXIVHDYRPAVLPFYEKWRKEHGPV-----FTYSMGNVVFLHVSRPDVVRDINLCVSLD 472 I D+ Y K+R+ P F V+ L +++ +++D S Sbjct: 58 ---IFQDH-------YNKFRESKAPFVGFFFFQSPAAFVIDLELAKQILIKDF----SNF 103 Query: 473 LGKSSYLKATHEPLFGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEP 652 K + +P+ + +G W R ++ F K+K M +V A + Sbjct: 104 SNKGIFYNEKDDPISAH-LFNLDGAQWRLLRNKLSSTFTSGKMKLMYPTVVSVANEFMTV 162 Query: 653 WEARVDKSGGTVDIKIDDDIRAYSADVISRTCFG---SSYVKGKKIFLKLRELQKAVSKP 823 +V K+ ++I D + ++ DVI FG +S K FL + + V K Sbjct: 163 MHEKVPKNSV---LEIRDLVARFTVDVIGTCAFGIQCNSLRDEKAEFLYFGK-RSLVDKR 218 Query: 824 NVLAEMTGLRFFPTKKN-----RQAWGLHKQVHRLILEIV----KESGEDKNLLRAILHS 976 + +R +P R A + + R++ E V KE + + + ++ Sbjct: 219 HGTLLNGFMRSYPKLARKLGMVRTAPHIQEFYSRIVTETVAVREKEHIKRNDFMDMLIEL 278 Query: 977 ASSSKVGL-------GEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQ 1135 + ++ L G ++ + AG+E+++ T + L L +P+ QD+VR Sbjct: 279 KNQKEMTLENGDVVRGLTMEEVLAQAFVFFIAGFETSSSTMGFALYELAKNPDIQDKVRA 338 Query: 1136 EVLEVC--GGRPLDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKLGG---VHIP 1300 EV EV + + + +K L V+ ETLRLY + RMA + + G I Sbjct: 339 EVEEVIEQHDQNFTYECTKDLKYLNQVLDETLRLYTIVPNLDRMAAKRYVVPGHPNFVIE 398 Query: 1301 KGVNIYIPVSTMHLDPKLWGPDAKEFNPARFSD----ARPQLHSYLPFGAGARTCLGQGF 1468 G ++ IP S +H DP ++ P+ EF P RFS RP + ++LPFG G R C+G F Sbjct: 399 AGQSVIIPSSAIHHDPSIY-PEPFEFRPERFSPEESAGRPSV-AWLPFGDGPRNCIGLRF 456
>Q9LTM7:C71BG_ARATH Cytochrome P450 71B16 - Arabidopsis thaliana (Mouse-ear cress)| Length = 502 Score = 90.1 bits (222), Expect = 3e-17 Identities = 88/350 (25%), Positives = 144/350 (41%), Gaps = 42/350 (12%) Frame = +2 Query: 542 GEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAY 721 GE W +RK + E F K +V+ LL + + + G + + + Sbjct: 119 GEEWRERRKFLVRELFCFKKVQYFGYIVEEECNLLV--KKLTESAVGRPPVDLSKSLFWL 176 Query: 722 SADVISRTCFGSSYVKGKKIFLKLRELQKAVSKPNVL-AEMTGLRFFP-----------T 865 +A ++ R FG S+ K F+ ++ + + + A T FFP + Sbjct: 177 AASILFRIAFGQSFHDNK--FIDEDKIDELIFETETAQASFTCSDFFPIAGLGWLADWIS 234 Query: 866 KKNRQA-----------------------WGLHKQVHRLILEIVKESGEDKNLLRAILHS 976 K+R W HK + ++L+++ + G+D +L I H Sbjct: 235 GKHRWLNNVFFKLDALFQRVIDDHSDPGRWKDHKDIVDVMLDVMHKQGKDDSLRLTIDH- 293 Query: 977 ASSSKVGLGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCG 1156 + F+ + I AG ++ A+T W + L +PE V+ E+ + G Sbjct: 294 ----------IKGFLTN----IIIAGIDTGALTMIWAMTELARNPELMKNVQGEIRDSFG 339 Query: 1157 GRP--LDSQSLQKMKNLTMVIQETLRLYP-AGAFVSRMALQELKLGGVHIPKGVNIYIPV 1327 + + L K+ L MVI+ET RL+P A + R + +K+ G IP I + Sbjct: 340 NNKERITKEDLNKVPFLNMVIKETFRLHPVAPLLLPRETMTHIKVQGYDIPPKRRILVNT 399 Query: 1328 STMHLDPKLWGPDAKEFNPARFS----DARPQLHSYLPFGAGARTCLGQG 1465 + DP LW + +EFNP RF D R Q LPFG+G R C G G Sbjct: 400 WAIGRDPTLW-INPEEFNPERFINNPVDYRGQHFELLPFGSGRRICPGMG 448
>P58050:C71BD_ARATH Cytochrome P450 71B13 - Arabidopsis thaliana (Mouse-ear cress)| Length = 496 Score = 90.1 bits (222), Expect = 3e-17 Identities = 94/400 (23%), Positives = 175/400 (43%), Gaps = 27/400 (6%) Frame = +2 Query: 359 KWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRGILK- 535 K +++GP+ +G V + S P+ V+D+ D ++L + L Sbjct: 55 KLSEKYGPLVYLKLGKVPSVVASTPETVKDVLKTFDKDCCSRAFLTYPARISYNLKDLAF 114 Query: 536 -SNGEAWAHQRKIIAPEFFLDK-VKGMVDLMVDSAQTLLEPWEARVDKSGGTVD--IKID 703 + W RK+ E + K VK ++ + + +E K +++ + ++ Sbjct: 115 APYSKYWKAVRKMTVVELYTAKRVKSFRNIREEEVASFVE-----FIKHSASLEEIVNLN 169 Query: 704 DDIRAYSADVISRTCFGSSYVKGKKIFLKLRELQKAVSKPNVLAEMTGLRFFPTKKN--R 877 + S VI R FG + ++G K+ E+ + VL +FP Sbjct: 170 QTLVKLSGSVICRVGFGIN-LEGSKLENTYEEVIHGTME--VLGSFAASDYFPVIGGIID 226 Query: 878 QAWGLHKQVHRLI----------LEIVKESGEDKNLLRAILHSASSSKVGLGEAENFIVD 1027 + GLH + ++ ++ E G K+ + +L ++GLGE + F + Sbjct: 227 RITGLHNKCEKVFKGTDSFFDHCIKHHLEDGGSKDDIVDLLLKVERGEIGLGEFQ-FTRN 285 Query: 1028 NCKSIYF----AGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGRP-LDSQSLQKM 1192 + K I AG +++ T W + L +P + + EV EV + + + ++ + Sbjct: 286 HTKGILLDILLAGVDTSGHTITWVMTHLIKNPRVMKKAQAEVREVIKNKDNITEEDIEGL 345 Query: 1193 KNLTMVIQETLRLYPAGAFVS-RMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWGPDA 1369 + L MV++ETLR+ P ++ R A +++K+GG +IPK I++ + +H +P +W D Sbjct: 346 EYLKMVVKETLRINPLVPLLTPREASKDVKIGGYNIPKKTWIHVNIWAIHRNPNVW-KDP 404 Query: 1370 KEFNPARFSDARPQL----HSYLPFGAGARTCLGQGFATA 1477 + F P RF D + LPFG+G R C G G A Sbjct: 405 EAFIPERFMDNQIDYKGLNFELLPFGSGRRICPGIGMGMA 444
>Q9Y8G7:C505_FUSOX Bifunctional P-450:NADPH-P450 reductase - Fusarium oxysporum| Length = 1066 Score = 90.1 bits (222), Expect = 3e-17 Identities = 102/434 (23%), Positives = 178/434 (41%), Gaps = 25/434 (5%) Frame = +2 Query: 374 HGPVFTYSMGNVVFLHVSRPDVVRDI----NLCVSLDLGKSSYLKATHEPLFGRGILKSN 541 +GP+F +G + VS ++ ++ +L S + H+ LF + N Sbjct: 37 YGPIFRLRLGAKAPIFVSSNSLINEVCDEKRFKKTLKSVLSQVREGVHDGLFTAFEDEPN 96 Query: 542 GEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAY 721 W +I+ P F ++GM M D A L + + G I D+ Sbjct: 97 ---WGKAHRILVPAFGPLSIRGMFPEMHDIATQLC----MKFARHGPRTPIDTSDNFTRL 149 Query: 722 SADVISRTCFGSSYVKGKKIFLKLRELQKAVSKPNVLAEMTGLR---------FFPTKKN 874 + D ++ + K EL + +G R F N Sbjct: 150 ALDTLALCAMDFRFYSYYK-----EELHPFIEAMGDFLTESGNRNRRPPFAPNFLYRAAN 204 Query: 875 RQAWG---LHKQVHRLILEIVKESGEDKNLLRAILHSASSSKVGLGEAENFIVDNCKSIY 1045 + +G L K V ++ K S D+ L A + + + G ++ I + + Sbjct: 205 EKFYGDIALMKSVADEVVAARKASPSDRKDLLAAMLNGVDPQTGEKLSDENITNQLITFL 264 Query: 1046 FAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGRPLDSQSLQKMKNLTMVIQETL 1225 AG+E+T+ T ++ + L +PE +V++EV EV G P+ + L K+ ++ V++ETL Sbjct: 265 IAGHETTSGTLSFAMYQLLKNPEAYSKVQKEVDEVVGRGPVLVEHLTKLPYISAVLRETL 324 Query: 1226 RLYPAGAFVSRMALQELKLGGVH-IPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARFSD- 1399 RL A+ + LGG + + KG + +S H+DP ++G DA +F P R D Sbjct: 325 RLNSPITAFGLEAIDDTFLGGKYLVKKGEIVTALLSRGHVDPVVYGNDADKFIPERMLDD 384 Query: 1400 -----ARPQLHSYLPFGAGARTCLGQGFATAEXXXXXXXXXXXFALRLS-PLYQHSPALK 1561 + + + PFG G R C+G+ FA E F ++ P Y Sbjct: 385 EFARLNKEYPNCWKPFGNGKRACIGRPFAWQESLLAMVVLFQNFNFTMTDPNYALEIKQT 444 Query: 1562 LIVEPE-FGVDITL 1600 L ++P+ F ++ TL Sbjct: 445 LTIKPDHFYINATL 458
>Q9VRB3:CP6V1_DROME Probable cytochrome P450 6v1 - Drosophila melanogaster (Fruit fly)| Length = 520 Score = 89.7 bits (221), Expect = 3e-17 Identities = 89/339 (26%), Positives = 142/339 (41%), Gaps = 36/339 (10%) Frame = +2 Query: 551 WAHQRKIIAPEFFLDKVKGMVDLMVDSAQTL------LEPWEARVDKSGGTVDIKIDDDI 712 W R +AP F K+K M LM + L L R D G + + I D Sbjct: 131 WREIRTRLAPAFAGAKLKQMFSLMEEIGCDLEWYLKRLTRDLRRGDAERGAI-VSIKDVC 189 Query: 713 RAYSADVISRTCFGSSYVKGKKIFLKLRELQKAVSKPNVLAEMTGLRFF------PTKKN 874 Y+ D+I+ FG + ++ + + +PNV + F P + Sbjct: 190 DLYNTDMIASIAFGLRSYSLRNTQSEIGSHCQDLFRPNVRRIIDLFVIFYLPKLVPLLRP 249 Query: 875 RQAWGLHKQVHRLILEIV---KESGED--KNLLRAILH-----SASSSKVGLGEAENFIV 1024 + H + R ++++V +E G D +L+ +L K +F+ Sbjct: 250 KLFTEPHAEFLRRVIQLVIEERERGGDLRNDLIEMLLTLKKEADLQQDKSHFTHHRDFLA 309 Query: 1025 DNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGRP---LDSQSLQKMK 1195 S AG E+ + + ++ L L P Q R+R+E+ E P L +++ +M+ Sbjct: 310 AQAASFEVAGIETCSASMSFALYELAKQPLMQSRLRREIREAFASNPNGRLTYEAVARME 369 Query: 1196 NLTMVIQETLRLYPAGAFVSRMALQELKL--------GGVHIPKGVNIYIPVSTMHLDPK 1351 L MV++ETLR YP + R K + +G+ ++I +H DPK Sbjct: 370 FLDMVVEETLRKYPIVPLLERECTPINKKRFYSLRPHAECYTRRGMPVFISNLAIHHDPK 429 Query: 1352 LWGPDAKEFNPARFSDARPQLH---SYLPFGAGARTCLG 1459 W PD F+P RFS A L SY+PFGAG R C+G Sbjct: 430 YW-PDPDRFDPERFSAANKALQAPMSYMPFGAGPRNCIG 467
>P00178:CP2B4_RABIT Cytochrome P450 2B4 - Oryctolagus cuniculus (Rabbit)| Length = 491 Score = 89.7 bits (221), Expect = 3e-17 Identities = 106/417 (25%), Positives = 183/417 (43%), Gaps = 34/417 (8%) Frame = +2 Query: 332 RPAVLPFYEKWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEP 511 R +L + + R+++G VFT +G+ + + D +R+ L + A +P Sbjct: 48 RKGLLRSFLRLREKYGDVFTVYLGSRPVVVLCGTDAIREA-LVDQAEAFSGRGKIAVVDP 106 Query: 512 LF-GRGILKSNGEAWAHQRKIIAP---EFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSG 679 +F G G++ +NGE W R+ +F + K + + + + + A+ L+E + KS Sbjct: 107 IFQGYGVIFANGERWRALRRFSLATMRDFGMGK-RSVEERIQEEARCLVE----ELRKSK 161 Query: 680 GTVDIKIDDDIRAYS--ADVISRTCFGSSYVKGKKIFLKLRELQ----KAVSK--PNVLA 835 G + +D+ + +S +++I FG + +FL+L +L +S V Sbjct: 162 GAL---LDNTLLFHSITSNIICSIVFGKRFDYKDPVFLRLLDLFFQSFSLISSFSSQVFE 218 Query: 836 EMTG-LRFFPTKKNRQAWGLHKQVHRLILEIVKESGEDKNLLRAILHSAS---------- 982 G L+ FP G H+Q++R + EI G+ RA L ++ Sbjct: 219 LFPGFLKHFP--------GTHRQIYRNLQEINTFIGQSVEKHRATLDPSNPRDFIDVYLL 270 Query: 983 ------SSKVGLGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVL 1144 S +N I+ S++FAG E+T+ T + +L+ +P +RV++E+ Sbjct: 271 RMEKDKSDPSSEFHHQNLIL-TVLSLFFAGTETTSTTLRYGFLLMLKYPHVTERVQKEIE 329 Query: 1145 EVCGG-RPLDSQSLQKMKNLTMVIQETLRLYPAGAF-VSRMALQELKLGGVHIPKGVNIY 1318 +V G RP KM VI E RL F V ++ + G IPK ++ Sbjct: 330 QVIGSHRPPALDDRAKMPYTDAVIHEIQRLGDLIPFGVPHTVTKDTQFRGYVIPKNTEVF 389 Query: 1319 IPVSTMHLDPKLWGPDAKEFNPARFSDARPQL---HSYLPFGAGARTCLGQGFATAE 1480 +S+ DP+ + FNP F DA L ++PF G R CLG+G A E Sbjct: 390 PVLSSALHDPRYF-ETPNTFNPGHFLDANGALKRNEGFMPFSLGKRICLGEGIARTE 445
>P11711:CP2A1_RAT Cytochrome P450 2A1 - Rattus norvegicus (Rat)| Length = 492 Score = 89.7 bits (221), Expect = 3e-17 Identities = 101/398 (25%), Positives = 182/398 (45%), Gaps = 27/398 (6%) Frame = +2 Query: 368 KEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLF-GRGILKSNG 544 + +GPVFT +G + + D V++ + + + +AT+ LF G G+ S+G Sbjct: 62 ERYGPVFTIHLGPRRVVVLYGYDAVKEALVDQAEEFSGRGE-QATYNTLFKGYGVAFSSG 120 Query: 545 EAWAHQRKIIAP---EFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIR 715 E R++ +F + K +G+ + +++ A L++ + GT ID I Sbjct: 121 ERAKQLRRLSIATLRDFGVGK-RGVEERILEEAGYLIKMLQ-------GTCGAPIDPTIY 172 Query: 716 AYS--ADVISRTCFGSSYVKGKKIFLKLRELQK-----AVSKPNVLAEM--TGLRFFPTK 868 ++VIS FG + FL L ++ A S L +M + +++ P Sbjct: 173 LSKTVSNVISSIVFGERFDYEDTEFLSLLQMMGQMNRFAASPTGQLYDMFHSVMKYLPGP 232 Query: 869 KNRQAWGLHKQVHRLILEIVKES------GEDKNLLRAILHSASSSKVGLGEAE-NFIVD 1027 + +Q + +++ ++E V+++ +N + + L K G E +V Sbjct: 233 Q-QQIIKVTQKLEDFMIEKVRQNHSTLDPNSPRNFIDSFLIRMQEEKNGNSEFHMKNLVM 291 Query: 1028 NCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCG-GRPLDSQSLQKMKNLT 1204 S++FAG E+ + T + +LL HP+ + +V +E+ +V G R + KM Sbjct: 292 TTLSLFFAGSETVSSTLRYGFLLLMKHPDVEAKVHEEIEQVIGRNRQPQYEDHMKMPYTQ 351 Query: 1205 MVIQETLR---LYPAGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWGPDAKE 1375 VI E R L P G + R ++ G +PKG +++ + ++ DPK + P K+ Sbjct: 352 AVINEIQRFSNLAPLG--IPRRIIKNTTFRGFFLPKGTDVFPILGSLMTDPKFF-PSPKD 408 Query: 1376 FNPARFSDARPQLH---SYLPFGAGARTCLGQGFATAE 1480 F+P F D + QL ++LPF G R CLG G A E Sbjct: 409 FDPQNFLDDKGQLKKNAAFLPFSTGKRFCLGDGLAKME 446
>Q9PUB4:CP26A_CHICK Cytochrome P450 26A1 - Gallus gallus (Chicken)| Length = 492 Score = 89.7 bits (221), Expect = 3e-17 Identities = 70/239 (29%), Positives = 115/239 (48%), Gaps = 10/239 (4%) Frame = +2 Query: 785 LKLRELQKAVSKPNVLAEMTGLRFFPTKKNRQAWGLHKQVHRLILEIVKESGEDKNLLRA 964 L+ R + A + N+ A+M ++ G +K +L++E + +GE N+ Sbjct: 235 LRARNIIHAKIEENIRAKMA---------RKEPEGGYKDALQLLMEHTQGNGEQLNMQE- 284 Query: 965 ILHSASSSKVGLGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVL 1144 + ++ + F G+E+TA A + LGLH + +VR+E L Sbjct: 285 ------------------LKESATELLFGGHETTASAATSLIAFLGLHHDVLQKVRKE-L 325 Query: 1145 EVCG-------GRPLDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKLGGVHIPK 1303 ++ G + L+ + L+++K VI+ETLRL P R+AL+ L+L G IPK Sbjct: 326 QLKGLLSGPNQEKQLNMEFLEQLKYTGCVIKETLRLSPPVPGGFRIALKTLELNGYQIPK 385 Query: 1304 GVNIYIPVSTMHLDPKLWGPDAKEFNPARFSDARPQ---LHSYLPFGAGARTCLGQGFA 1471 G N+ + H L+ D EFNP RF P+ S++PFG G R+C+G+ FA Sbjct: 386 GWNVIYSICDTHDVADLF-TDKDEFNPDRFMSPSPEDSSRFSFIPFGGGLRSCVGKEFA 443
>Q9LIP3:C71BY_ARATH Cytochrome P450 71B37 - Arabidopsis thaliana (Mouse-ear cress)| Length = 500 Score = 89.7 bits (221), Expect = 3e-17 Identities = 96/401 (23%), Positives = 166/401 (41%), Gaps = 31/401 (7%) Frame = +2 Query: 344 LPFYEKWR--KEHGPVFTYSMGNVVFLHVSRPDV------VRDINLCVSLDLGKSSYLKA 499 LP W K++GPV G++ + VS + + D+N C L L Sbjct: 50 LPHQSLWSLSKKYGPVMLLKFGSIPTVVVSSSETAKQALKIHDLNCCSRPSLAGPRALSY 109 Query: 500 THEPLFGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVD-LMVDSAQTLLEPWEARVDKS 676 + + + + W R++ E F K ++ + + + L+ + + + Sbjct: 110 NYLDI----VFSPFNDYWKELRRMCVQELFSPKQVHLIQPIREEEVKKLMNSFS---ESA 162 Query: 677 GGTVDIKIDDDIRAYSADVISRTCFGSSYVKGKKI------------FLKLRELQKAVSK 820 + + + + + + VI + FG S+ +G + FL L + Sbjct: 163 AQKTPVNLSEKLASLTVGVICKAAFGVSF-QGTVLNSDNFDKLIHDAFLFLGSFSASDYF 221 Query: 821 PNV---LAEMTGLRFFPTKKNRQAWGLHKQVHRLILEIVKESGEDKNLLRAILHSASSSK 991 PNV + +TGL+ + R ++Q+ L + KE ED L L + Sbjct: 222 PNVGWIIDWLTGLQGQRERSVRGLDAFYEQMFDLHKQGNKEGVEDFVDLLLKLEK-EETV 280 Query: 992 VGLGE-AENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGRPL 1168 +G G+ N I ++ G ++A+T W + L +P +V+ E+ GG+ + Sbjct: 281 LGYGKLTRNHIKAVLMNVLLGGIGTSAITMTWAMTELMRNPRVMKKVQSEIRNQIGGKSM 340 Query: 1169 DS-QSLQKMKNLTMVIQETLRLYP-AGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHL 1342 + ++ L MVI ET RL+P A V R + E ++ G IP +Y+ V + Sbjct: 341 ICLDDIDQLHYLKMVINETWRLHPPAPLLVPREVMSEFEINGYTIPAKTRLYVNVWGIGR 400 Query: 1343 DPKLWGPDAKEFNPARF----SDARPQLHSYLPFGAGARTC 1453 DP W D +EF P RF DA+ Q LPFG+G R C Sbjct: 401 DPDTW-KDPEEFLPERFVNSNIDAKGQNFELLPFGSGRRMC 440
>O65438:C71AR_ARATH Cytochrome P450 71A27 - Arabidopsis thaliana (Mouse-ear cress)| Length = 499 Score = 89.7 bits (221), Expect = 3e-17 Identities = 94/415 (22%), Positives = 164/415 (39%), Gaps = 31/415 (7%) Frame = +2 Query: 320 VHDYRPAVLPFYEKWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKA 499 +H P + +GP+ G V L VS PDV DI L KA Sbjct: 46 LHQLGPNPHRYLHSLSLRYGPLMLLHFGRVPVLVVSCPDVTNDIMKTHDLKFANRPKSKA 105 Query: 500 THEPLFGRG----ILKSNGEAWAHQRKIIAPEFFLDK-VKGMVDLMVDSAQTLLEPWEAR 664 + +F G I GE W + + +K V+ +L + + + E E Sbjct: 106 IN--IFMEGGRDIIFGPYGEDWKSMKSLGVVHLLNNKMVRSFENLREEEIKVMTEKLE-- 161 Query: 665 VDKSGGTVDIKIDDDIRAYSADVISRTCFGSSYVKGKKIFLKLRELQKAVSKPNVL---A 835 + S + + + + + D+I R G Y E + + N++ + Sbjct: 162 -EASSSSSSVNLSKLLMTLTNDIICRITLGRKY----------NEEEGGIDIKNLVMTSS 210 Query: 836 EMTGLRFFPTKKNRQAW------------GLHKQVHRLILEIVKES-----GEDKNLLRA 964 E G FF AW ++ ++ + +V+E E + + Sbjct: 211 EFFGKFFFGDFIPSLAWIDWISGIDDKMKDINNKLDCFLDSMVQEHVDADHKEPSDFIDM 270 Query: 965 ILHSASSSKVGLGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVL 1144 +L + ++ K ++F+G +TA W + L HPE +++ E+ Sbjct: 271 LLLIQKDKTKRFKFDRSDLILILKDMFFSGTATTASQLEWTMTELMRHPECMKKLQDEIN 330 Query: 1145 EVCGGR-PLDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKLGGVHIPKGVNIYI 1321 + + ++KM L VI+E LRL+P+G + R+ ++++L G I G ++ I Sbjct: 331 SFSTHNLNVTEKEVEKMNYLHCVIKEGLRLHPSGPLLFRLPSEDVQLKGYDISAGTHVII 390 Query: 1322 PVSTMHLDPKLWGPDAKEFNPAR-----FSDARPQLHSYLPFGAGARTCLGQGFA 1471 + +P +WG DA E+ P R F R ++PFGAG R C G GF+ Sbjct: 391 NAWALQRNPAIWGLDANEYRPERHFWYEFGFQRTD-SKFVPFGAGRRLCPGIGFS 444
>Q9V769:C6A22_DROME Cytochrome P450 6a22 - Drosophila melanogaster (Fruit fly)| Length = 499 Score = 89.7 bits (221), Expect = 3e-17 Identities = 114/474 (24%), Positives = 198/474 (41%), Gaps = 32/474 (6%) Frame = +2 Query: 143 LALYLYYTVWVVPQRLLAGFRRQGIGGPRPSFPYGNMADXXXXXXXXXXXXXXXXXXXIV 322 L + L W V R + + R+GIG FP GNM Sbjct: 8 LLIALAVGFWFVRTRY-SYWTRRGIGSEPARFPVGNMEGFRKNKH--------------- 51 Query: 323 HDYRPAVLPFYEKWRKEHGPVFTYSMGNVVFLHVSRPDV-VRDINLCVSLDL-------G 478 + V P YEK++ P + M + RP V V D+ L + + Sbjct: 52 --FIDIVTPIYEKFKGNGAPFAGFFM-------MLRPVVLVTDLELAKQILIQDFANFED 102 Query: 479 KSSYLKATHEPLFGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWE 658 + Y +PL G + + +G W R+ ++P F K+K M + + + L + Sbjct: 103 RGMYHNERDDPLTGH-LFRIDGPKWRPLRQKMSPTFTSAKMKYMFPTVCEVGEELTQVCG 161 Query: 659 ARVDKSGGTVDIKIDDDIRAYSADVISRTCFGSSY-----------VKGKKIFLKLRELQ 805 D + + ++I D + Y++DVI R FG + G++ F + R + Sbjct: 162 ELADNAMCGI-LEIGDLMARYTSDVIGRCAFGVECNGLRNPEAEFAIMGRRAFSERRHCK 220 Query: 806 KAVSKPNVLAEMTGLRFFPTKKNRQAWGLHKQVHRLILEIVKES---GEDKNLLRAILHS 976 E+ RF ++ +H+ + + IV+E+ E++ ++R+ + Sbjct: 221 LVDGFIESFPEVA--RFLRMRQ------IHQDITDFYVGIVRETVKQREEQGIVRSDFMN 272 Query: 977 ASSSKVGLGEAENFIVDNCKSIYFA-GYESTAVTAAWCLMLLGLHPEWQDRVRQEV---L 1144 GE + I+FA G++++A T + L L P Q ++R+E+ L Sbjct: 273 LLIEMKQRGELTIEEMAAQAFIFFAAGFDTSASTLGFALYELAKQPALQAKLREEIDQAL 332 Query: 1145 EVCGGRPLDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKLGG---VHIPKGVNI 1315 + G S+Q+++ + +VI ETLR YP ++R++ G +I G + Sbjct: 333 RLHNGE-FTYDSMQELRYMELVIAETLRKYPILPQLTRISRHLYAAKGDRHFYIEPGQML 391 Query: 1316 YIPVSTMHLDPKLWGPDAKEFNPARF---SDARPQLHSYLPFGAGARTCLGQGF 1468 IPV +H DP L+ P+ +F P RF A+ ++LPFG G R C+G F Sbjct: 392 LIPVYGIHHDPALY-PEPHKFIPERFLADQLAQRPTAAWLPFGDGPRNCIGMRF 444
>Q9VYY4:C4G15_DROME Cytochrome P450 4g15 - Drosophila melanogaster (Fruit fly)| Length = 574 Score = 89.7 bits (221), Expect = 3e-17 Identities = 60/187 (32%), Positives = 100/187 (53%), Gaps = 9/187 (4%) Frame = +2 Query: 938 GEDKNL--LRAILHSASSSKVGLGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHP 1111 GE K L L +L SA + G + I + +I F G+++TA +++ L L+G+H Sbjct: 343 GEKKRLAFLDLMLESAQN---GALITDTEIKEQVDTIMFEGHDTTAAGSSFFLSLMGIHQ 399 Query: 1112 EWQDRVRQEVLEVCGG--RPLDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKL- 1282 + QDRV E+ + G RP Q +MK L + ETLR+YP ++R ++LKL Sbjct: 400 DIQDRVLAELDSIFGDSQRPATFQDTLEMKYLERCLMETLRMYPPVPLIARELQEDLKLN 459 Query: 1283 -GGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARF---SDARPQLHSYLPFGAGART 1450 G IP+G + + +H +PK++ + F+P F A ++++PF AG R+ Sbjct: 460 SGNYVIPRGATVTVATVLLHRNPKVYA-NPNVFDPDNFLPERQANRHYYAFVPFSAGPRS 518 Query: 1451 CLGQGFA 1471 C+G+ +A Sbjct: 519 CVGRKYA 525 Score = 44.3 bits (103), Expect = 0.002 Identities = 31/108 (28%), Positives = 56/108 (51%), Gaps = 2/108 (1%) Frame = +2 Query: 443 RDINLCVS--LDLGKSSYLKATHEPLFGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVD 616 RD+ L +S + + K+S K +P G G+L S G+ W RK+IAP F L+ +K ++ Sbjct: 99 RDVELLLSSHVYIDKASEYKF-FKPWLGDGLLISTGQKWRSHRKLIAPTFHLNVLKSFIE 157 Query: 617 LMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAYSADVISRTCFGSS 760 L ++++ ++ A + G T D D + + +++ T G S Sbjct: 158 LFNENSRNVVRKLRA---EDGRTFD--CHDYMSEATVEILLETAMGVS 200
>Q9VHP4:CP313_DROME Probable cytochrome P450 313b1 - Drosophila melanogaster (Fruit fly)| Length = 502 Score = 89.4 bits (220), Expect = 4e-17 Identities = 94/394 (23%), Positives = 166/394 (42%), Gaps = 36/394 (9%) Frame = +2 Query: 398 MGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRGILKSNGEAWAHQRKIIA 577 MG FL+++ P V I L + K + + + G G+ S+ W R++I Sbjct: 72 MGTSCFLYINDPHSVEQI-LNSTHCTNKGDFYRFMSSAI-GDGLFTSSSPRWHKHRRLIN 129 Query: 578 PEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAYSADVISRTCFGS 757 P F + + + A+ LL+ E + G ++I + V+ C Sbjct: 130 PAFGRQILSNFLPIFNAEAEVLLQKLELEGVQHGKRLEI-----YQILKKIVLEAAC--- 181 Query: 758 SYVKGKK----------IFLKLRELQKAVSK--------PNVLAEMTGLRFFPTKKNRQA 883 GKK IF L + K P+++ +GL K Sbjct: 182 QTTMGKKMNFQHDGSLCIFKAYNGLTEVCVKRMLSPWLYPDLIYRRSGLFRLQQKVVGIL 241 Query: 884 WGLHKQVHRLILEIVKESG---------EDKNLLRAILHSASSSKVGLGEAE-NFIVDNC 1033 +G +Q+ I+ +V + E + +AI V G+ + D Sbjct: 242 FGFIEQLLEPIVSVVAANSNPDQQRSEMEMRGKSKAIFIEQVREHVERGQLSWQDVRDEA 301 Query: 1034 KSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQE-VLEVCGGRPLDSQSLQKMKNLTMV 1210 A +E+T+ + ++ L +HP +Q+++ +E V E+ ++ + LQ+++ MV Sbjct: 302 NVTIAATFETTSTALYFTILCLAMHPCYQEKLHKELVTELPPSGDINLEQLQRLEYTEMV 361 Query: 1211 IQETLRLYPAGAFVSRMALQELKL----GGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEF 1378 I E +RL+ V R A Q+++L G IP+G I I + M D ++WGP ++ + Sbjct: 362 INEAMRLFAPVPMVLRSADQDIQLKRGDGEFLIPRGTQIGIDIYNMQRDERVWGPLSRTY 421 Query: 1379 NP-ARFSDARPQLH--SYLPFGAGARTCLGQGFA 1471 NP A F PQ H +++PF G R C+G +A Sbjct: 422 NPDAHFGLDSPQRHAFAFVPFTKGLRMCIGYRYA 455
>Q01361:CP2DE_BOVIN Cytochrome P450 2D14 - Bos taurus (Bovine)| Length = 500 Score = 89.4 bits (220), Expect = 4e-17 Identities = 94/354 (26%), Positives = 153/354 (43%), Gaps = 36/354 (10%) Frame = +2 Query: 527 ILKSNGEAWAHQRKIIAP---EFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIK 697 IL G+AW QR+ F L K K + + + A L + + + +D+ Sbjct: 123 ILARYGDAWREQRRFSLTTLRNFGLGK-KSLEQWVTEEASCLCAAFADQAGRPFSPMDL- 180 Query: 698 IDDDIRAYSADVISRTCFGSSYVKGKKIFLKLREL------------QKAVSKPNVLAEM 841 + ++VI+ FG + +KL +L +K V VL + Sbjct: 181 ----LNKAVSNVIASLTFGCRFEYNDPRIIKLLDLTEDGLKEEFNLVRKVVEAVPVLLSI 236 Query: 842 TGL--RFFPTKKNRQAWGLHKQVHRLILEIVKE-------SGEDKNLLRAILHSASSSKV 994 GL R FP +K A LI E++ E + ++L A L +K Sbjct: 237 PGLAARVFPAQKAFMA---------LIDELIAEQKMTRDPTQPPRHLTDAFLDEVKEAK- 286 Query: 995 GLGEAENFIVDN-----CKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGG 1159 G E+ D ++ AG +T+ T AW L+L+ LHP+ Q RV+QE+ EV G Sbjct: 287 --GNPESSFNDENLRLVVADLFSAGMVTTSTTLAWALLLMILHPDVQRRVQQEIDEVIGQ 344 Query: 1160 RPLDSQSLQKMKNLTM-VIQETLR---LYPAGAFVSRMALQELKLGGVHIPKGVNIYIPV 1327 Q + T+ V+ E R + P G + M +++++ G HIPKG + + Sbjct: 345 VRRPEMGDQALMPFTVAVVHEVQRFADIVPLG--LPHMTSRDIEVQGFHIPKGTTLITNL 402 Query: 1328 STMHLDPKLWGPDAKEFNPARFSDARPQL---HSYLPFGAGARTCLGQGFATAE 1480 S++ D +W + F+P F DA+ + +++PF AG R CLG+ A E Sbjct: 403 SSVLKDETVWEKPFR-FHPEHFLDAQGRFVKQEAFIPFSAGRRACLGEPLARME 455
>Q29497:CP17A_SHEEP Cytochrome P450 17A1 - Ovis aries (Sheep)| Length = 509 Score = 89.4 bits (220), Expect = 4e-17 Identities = 100/442 (22%), Positives = 194/442 (43%), Gaps = 36/442 (8%) Frame = +2 Query: 359 KWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFG--RGI- 529 K ++++GP++++ +G+ + + + R++ L + + AT + L +GI Sbjct: 55 KLQEKYGPIYSFRLGSKTTVMIGHHQLAREVLLKKGKEFSGRPKV-ATLDILSDNQKGIA 113 Query: 530 LKSNGEAWAHQRKIIAPEFFLDKVKGM-VDLMVDSAQTLLEPWEARVDKSGGTVDIKIDD 706 +G W RK++ F L K + ++ +++ +L + A + G ++D+ + Sbjct: 114 FADHGAHWQLHRKLVLNAFALFKDGNLKLEKIINQEANVLCDFLAT--QHGQSIDLS--E 169 Query: 707 DIRAYSADVISRTCFGSSYVKGKKIFLKLRELQKAV----SKPNVLAEMTGLRFFPTKKN 874 + ++IS CF S+ ++ + + K +L L+ FP+K Sbjct: 170 PLSLAVTNIISFICFNFSFKNEDPALKAIQNVNDGILEVLGKEVLLDIFPALKIFPSKAM 229 Query: 875 RQAWGLHKQVHRLILEIVKESGED--KNLLRAILHSASSSKVGLG------EAENFIVDN 1030 + G + + L+ EI+++ E+ + + +LH +KV E ++ ++ N Sbjct: 230 EKMKGCVETRNELLSEILEKCQENFTSDSITNLLHILMQAKVNADNNNTGPEQDSKLLSN 289 Query: 1031 ------CKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCG-GRPLDSQSLQK 1189 I+ AG E+T W + L HP + R++ + + G R + Sbjct: 290 RHMLATIADIFGAGVETTTSVIKWIVAYLLHHPSLKKRIQDSIDQNIGFNRTPTISDRNR 349 Query: 1190 MKNLTMVIQETLRLYP-AGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWG-P 1363 + L I+E LR+ P A + A+ + +G + I KG ++ + + +H + K W P Sbjct: 350 LVLLEATIREVLRIRPVAPMLIPHKAIIDSSIGDLTIDKGTDVVVNLWALHHNEKEWQQP 409 Query: 1364 DAKEFNPARFSDAR------PQLHSYLPFGAGARTCLGQGFATAEXXXXXXXXXXXFALR 1525 D F P RF D P L SYLPFGAG R+C+G+ A E F L Sbjct: 410 DL--FMPERFLDPTGTQLISPSL-SYLPFGAGPRSCVGEMLARQELFLFMSRLLQRFNLE 466 Query: 1526 LS-----PLYQHSPALKLIVEP 1576 + P + +P+L L ++P Sbjct: 467 IPDDGKLPSLEGNPSLVLQIKP 488
>Q9LTM6:C71BH_ARATH Cytochrome P450 71B17 - Arabidopsis thaliana (Mouse-ear cress)| Length = 502 Score = 89.4 bits (220), Expect = 4e-17 Identities = 102/415 (24%), Positives = 175/415 (42%), Gaps = 39/415 (9%) Frame = +2 Query: 353 YEKWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRGIL 532 + + + G V +G V +S + ++ LD L + L RG Sbjct: 54 FRRLAERTGHVMLLHLGFVPVTVISSREAAEEVLRTHDLDCCSRPNLVGSR--LISRGFK 111 Query: 533 KSN----GEAWAHQRKIIAPEFFLDK-VKGMVDLMVDSAQTLLEPW-EARVDKSGGTVDI 694 N GE W +R+ + E F K ++ + + L++ E+ VD+S + Sbjct: 112 DLNFTPYGEEWKERRRFLVGELFCSKKLQSFIYIKEVECNFLVKKLSESAVDQS----PV 167 Query: 695 KIDDDIRAYSADVISRTCFGSSYVKGKKIFLKLRELQKAVSKPNVL-AEMTGLRFFPTKK 871 + + +A ++ R FG S+ + + F ++ + V + T FFP Sbjct: 168 DLSKTLFWLAASILFRVAFGQSFHESE--FTDTDKIDELVFETETAQGSFTCSDFFPIAG 225 Query: 872 NRQAW------GLHKQVHRLILEIVK-------------ESGEDKNLLRAILHSASSSKV 994 W G HK+++ + L++ S + K+++ +L K Sbjct: 226 --LGWLVDWISGQHKRLNDVFLKLDALLQHVIDDHSNPGRSKDHKDIVDVMLDVMH--KQ 281 Query: 995 GLGEAENFIVDNCK----SIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGG- 1159 G ++ +D+ K +I AG ++ A+T W + L +PE +V+ E+ + G Sbjct: 282 GKDDSLRLTIDHIKGLLTNIIIAGIDTGALTMIWTMTELARNPEIMKKVQGEIRDRLGNN 341 Query: 1160 -RPLDSQSLQKMKNLTMVIQETLRLYP-AGAFVSRMALQELKLGGVHIPKGVNIYIPVST 1333 + + L K+ L +VI+ET RL+P A + R + +K+ G IP I + Sbjct: 342 RERITKEDLDKVPFLNLVIKETFRLHPVAPLLLPRETMAHVKVQGYDIPPKRRILVNAWA 401 Query: 1334 MHLDPKLWGPDAKEFNPARFSDA----RPQLHSYLPFGAGARTCLG--QGFATAE 1480 + DPKLW D +EF P RF D+ R Q LPFG+G R C G G AT E Sbjct: 402 IGRDPKLW-TDPEEFKPERFIDSPVDYRGQHFELLPFGSGRRICPGMAMGMATLE 455
>Q9LVD2:C71BA_ARATH Cytochrome P450 71B10 - Arabidopsis thaliana (Mouse-ear cress)| Length = 502 Score = 89.4 bits (220), Expect = 4e-17 Identities = 95/407 (23%), Positives = 169/407 (41%), Gaps = 33/407 (8%) Frame = +2 Query: 359 KWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRGILKS 538 K K++GPV +G V + VS P+ + + L L+ T + + + Sbjct: 56 KLSKKYGPVMLLKLGRVPTVIVSTPETAKQVLKDYDLHCCSRPSLEGTRKLSYNYLDIAF 115 Query: 539 N--GEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEP-WEARVDKSGGTVD----IK 697 + + W RK+ E F +K ++S Q + E E +D + + Sbjct: 116 SRFDDYWKELRKLCVEELFCNK-------RINSIQPIKEAEMEKLIDSIAESASQKTLVN 168 Query: 698 IDDDIRAYSADVISRTCFGSSYV-------KGKKIFLKLRELQKAVSKPN-------VLA 835 + D + + +VI + FG ++ K + + + E+ + S + ++ Sbjct: 169 LSDTFLSLNVNVICKAVFGVNFQGTVLNNDKFQDLVHEALEMLGSFSASDFFPYVGWIVD 228 Query: 836 EMTGLRFFPTKKNRQAWGLHKQVHRLILEIVKESGEDKNLLRAILHSASSSKVGLGE-AE 1012 TGL + R ++Q+ L L+ +E ED + + + +G G+ Sbjct: 229 WFTGLHARRERSVRDLDAFYEQMIDLHLQKNREESEDDFVDLLLRLEKEEAVLGYGKLTR 288 Query: 1013 NFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGG----RPLDSQS 1180 N I +I G ++A+T W + L +P +V+ E+ G R + Sbjct: 289 NHIKAILMNILLGGINTSAITMTWAMAELIRNPRVMKKVQSEIRAQIGKNNKTRIISLDE 348 Query: 1181 LQKMKNLTMVIQETLRLYP-AGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLW 1357 + + L MVI+ET RL+P A V R + E K+ G I +++ V + DP++W Sbjct: 349 INHLSYLNMVIKETCRLHPVAPLLVPREVISEFKINGYTIQPKTRLHVNVWAIGRDPEIW 408 Query: 1358 GPDAKEFNPARFS----DARPQLHSYLPFGAGARTC--LGQGFATAE 1480 D +EF P RF D + Q + LPFG+G R C + G T E Sbjct: 409 -KDPEEFLPERFMDCDIDVKGQDYELLPFGSGRRICPAVYMGITTVE 454
>P30608:CP52F_CANTR Cytochrome P450 52A6 - Candida tropicalis (Yeast)| Length = 524 Score = 89.0 bits (219), Expect = 6e-17 Identities = 99/365 (27%), Positives = 159/365 (43%), Gaps = 41/365 (11%) Frame = +2 Query: 509 PLFGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTV 688 PL G GI +GE W H R ++ P+F D++ G V + Q L + + +++K G T Sbjct: 132 PLLGDGIFTLDGEGWKHSRAMLRPQFARDQI-GHVKALEPHIQILAK--QIKLNK-GKTF 187 Query: 689 DIKIDDDIRAYSADVISRTCFGSSYVKGKKIFLKLRELQKAVSKPN-VLAEMTGLRFFPT 865 DI+ + ++ D + FG S L + + + N A T + T Sbjct: 188 DIQ--ELFFRFTVDTATEFLFGESVHSLYDEKLGIPTPNEIPGRDNFATAFNTSQHYLAT 245 Query: 866 KKNRQAW----------GLHKQVHRLI-------LEIVKESGEDKN-----LLRAILHSA 979 + Q + + +VH L L E E+K+ L ++ Sbjct: 246 RTYSQTFYFLTNPKEFRDCNAKVHYLAKYFVNKALNFTPEEIEEKSKSGYVFLYELVKQT 305 Query: 980 SSSKVGLGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGG 1159 KV + D +I AG ++TA ++ + L HPE ++R+E+ EV G Sbjct: 306 RDPKV--------LQDQLLNIMVAGRDTTAGLLSFAMFELARHPEIWSKLREEI-EVNFG 356 Query: 1160 RPLDS-------QSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKL---GG------V 1291 +S +SL++ + L ++ ETLR+YP+ SR A ++ L GG + Sbjct: 357 VGEESRVEEITFESLKRCEYLKAILNETLRMYPSVPVNSRTATRDTTLPRGGGPNGTDPI 416 Query: 1292 HIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPAR-FSDARPQLH-SYLPFGAGARTCLGQG 1465 IPKG + V H + +G DA +F P R F + +L +Y+PF G R CLGQ Sbjct: 417 FIPKGSTVAYIVYKTHRLEEYYGKDADDFRPERWFEPSTKKLGWAYVPFNGGPRICLGQQ 476 Query: 1466 FATAE 1480 FA E Sbjct: 477 FALTE 481
>Q759W0:CP51_ASHGO Cytochrome P450 51 - Ashbya gossypii (Yeast) (Eremothecium gossypii)| Length = 529 Score = 89.0 bits (219), Expect = 6e-17 Identities = 104/461 (22%), Positives = 205/461 (44%), Gaps = 37/461 (8%) Frame = +2 Query: 329 YRPAVLPFYEKWRKEHGPVFTYSM-GNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATH 505 Y A F+ K ++++G VF + + G V+ +++ +N ++ + +Y K T Sbjct: 70 YGRAPYEFFGKCQQKYGDVFAFMLLGRVMTVYLGTKGHEFILNAKLAEVSAEEAYTKLT- 128 Query: 506 EPLFGRGILKS-NGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARV--DKS 676 P+FG G++ Q+K + + V +++D + L + + ++S Sbjct: 129 TPVFGEGVVYDCPNHRLMEQKKFCKNALSTEAFRRYVPMVMDEVRKYLRTSKHFMMNERS 188 Query: 677 GGTVDI-KIDDDIRAYSADVISRTCFGS---SYVKGKKIFLKLRELQKAVSKPNVLAEMT 844 G V++ + ++ ++A SR+ G+ S + +L +L K + N + Sbjct: 189 SGVVNVMETQPEMTIFTA---SRSLLGAEMHSMLDADFAYL-YADLDKGFTPLNFV---- 240 Query: 845 GLRFFPTKKNRQAWGLHKQVHRLILEIVKESG-----EDKNLLRAILHSASSSKVGLGEA 1009 R P R+ + + +++++ +D++L+ A++ SA K G+ Sbjct: 241 -FRDLPLDNYRRRDNAQRTISSTYMKVIERRRKNNDVQDRDLIDALMTSAQY-KDGVKMT 298 Query: 1010 ENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVC--GGRPLDSQSL 1183 + I + + G ++A T+AW L+ L P+ Q+ + +E + V G + L + L Sbjct: 299 DQQIANLLIGVLMGGQHTSAATSAWVLLHLAERPDIQEELYEEQMRVLDGGAKELTYELL 358 Query: 1184 QKMKNLTMVIQETLRLYPAGAFVSRMALQELKLGGVH--IPKGVNIYIPVSTMHLDPKLW 1357 Q+M L VI+ETLR++ + R +++ + IPK + HL + + Sbjct: 359 QEMPLLNQVIKETLRMHHPLHSLFRKVTRDMPVPNTSYVIPKDHYVLASPGFCHLSEEYF 418 Query: 1358 GPDAKEFNPARF-SDARPQLHS------------------YLPFGAGARTCLGQGFATAE 1480 P+AKEFNP R+ +DA + + YLPFG G C+G+GFA + Sbjct: 419 -PNAKEFNPHRWDNDAASSVSTGEKVDYGFGAISKGVSSPYLPFGGGRHRCIGEGFAYMQ 477 Query: 1481 XXXXXXXXXXXFALRLSPLYQHSPA-LKLIVEPEFGVDITL 1600 F++ + + H PA +K + P+F +TL Sbjct: 478 -------LGTIFSVVVRSMKWHFPADMKGVPNPDFTSMVTL 511
>O54750:CP2J6_MOUSE Cytochrome P450 2J6 - Mus musculus (Mouse)| Length = 501 Score = 89.0 bits (219), Expect = 6e-17 Identities = 101/440 (22%), Positives = 186/440 (42%), Gaps = 26/440 (5%) Frame = +2 Query: 368 KEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGR-GILKSNG 544 K++G +F+ ++G++ + ++ ++++ + ++ + L E + + G++ S+G Sbjct: 73 KKYGNIFSLNLGDITSVVITGLPLIKEALTQMEQNI-MNRPLSVMQERISNKNGLIFSSG 131 Query: 545 EAWAHQRK---IIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIR 715 + W QR+ + F L K K + + M + A L+E K I++ + Sbjct: 132 QIWKEQRRFALMTLRNFGLGK-KSLEERMQEEASHLVEAIREEEGKPFNP-HFSINNAV- 188 Query: 716 AYSADVISRTCFGSSYVKGKKIFLKLRELQKAVSKPNVLAEMTGLRFFPTKKNRQAWGLH 895 +++I FG + F ++ L V FP + G H Sbjct: 189 ---SNIICSVTFGERFDYHDSRFQEMLRLLDEVMYLETTMISQLYNIFPWIM-KYIPGSH 244 Query: 896 KQVHR-----------LILEIVKESGED--KNLLRAILHSASS--SKVGLGEAENFIVDN 1030 ++V R +I + K+ D ++ + A L + K EN I Sbjct: 245 QKVFRNWEKLKLFVSCMIDDHRKDWNPDEPRDFIDAFLKEMTKYPEKTTSFNEENLICST 304 Query: 1031 CKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCG----GRPLDSQSLQKMKN 1198 ++FAG E+T+ T W L+ + L+PE Q++V+ E+ V G R D +S+ Sbjct: 305 L-DLFFAGTETTSTTLRWALLYMALYPEVQEKVQAEIDRVIGQKRAARLADRESMPYTNA 363 Query: 1199 LTMVIQETLRLYPAGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWG-PDAKE 1375 + ++ + P V R + L G H+PKG + ++ +H DPK W PD Sbjct: 364 VIHEVRRMGNIIPLN--VPREVAMDTNLNGFHLPKGTMVLTNLTALHRDPKEWATPDV-- 419 Query: 1376 FNPARF--SDARPQLHSYLPFGAGARTCLGQGFATAEXXXXXXXXXXXFALRLSPLYQHS 1549 FNP F + + S+LPF G R CLG+ A +E F L + + Sbjct: 420 FNPEHFLENGQFKKRESFLPFSMGKRACLGEQLARSE--------LFIFFTSLMQKFTFN 471 Query: 1550 PALKLIVEPEFGVDITLTKV 1609 P + + P+F +TL+ V Sbjct: 472 PPINEKLSPKFRNGLTLSPV 491
>Q9V773:C6A20_DROME Probable cytochrome P450 6a20 - Drosophila melanogaster (Fruit fly)| Length = 501 Score = 89.0 bits (219), Expect = 6e-17 Identities = 106/468 (22%), Positives = 195/468 (41%), Gaps = 32/468 (6%) Frame = +2 Query: 161 YTVWVVPQRLLAGFRRQGIGGPRPSFPYGNMADXXXXXXXXXXXXXXXXXXXIVHDYRPA 340 + W V Q ++R+GI P PYGN ++ VH + Sbjct: 14 FVAWYVHQHFNY-WKRRGIPHDEPKIPYGNTSELMKT----------------VH-FADI 55 Query: 341 VLPFYEKWR-KEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDL-------GKSSYLK 496 Y K R K GP + +++ R VV DI+ ++ + + + Sbjct: 56 FKRTYNKLRNKTDGPFVGF------YMYFKRMVVVTDIDFAKTVLIREFDKFHDRGVFHN 109 Query: 497 ATHEPLFGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKS 676 +PL ++ +G+ W R+ + P F K+K M ++ L+ + S Sbjct: 110 ERDDPL-SANLVNIDGQKWKTLRQKLTPTFTSGKMKTMFPTILTVGDELIRVFGETA--S 166 Query: 677 GGTVDIKIDDDIRAYSADVISRTCFGS-----SYVKGKKIFLKLRELQKAVSKPNVLAEM 841 + ++I + + ++ADVI FG S K K + + + + ++ + Sbjct: 167 ADSDSMEITNVVARFTADVIGSCAFGLDCHSLSDPKAKFVQMGTTAITERRHGKSMDLLL 226 Query: 842 TGLRFFPTKKNRQAWGLHKQVHRLILEIVKESGEDKNLLRAILHSASSSKVGL------G 1003 G K +A ++V + I++++ + + H + + G Sbjct: 227 FGAPELAAKLRMKA--TVQEVEDFYMNIIRDTVDYRVKNNVKRHDFVDMLIEMKLKFDNG 284 Query: 1004 EAENFIVDN-----CKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQE---VLEVCGG 1159 + EN + N + AG+E+++ T + L L H + QD++R E VL+ G Sbjct: 285 DKENGLTFNEIAAQAFIFFLAGFETSSTTMGFALYELACHQDIQDKLRTEINTVLKQHNG 344 Query: 1160 RPLDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKLGG--VHIPKGVNIYIPVST 1333 + LD S+++M L VI ET+R P + R+A Q + +I KG + +P Sbjct: 345 K-LDYDSMREMTYLEKVIDETMRKRPVVGHLIRVATQHYQHTNPKYNIEKGTGVIVPTLA 403 Query: 1334 MHLDPKLWGPDAKEFNPARFSDARPQLH---SYLPFGAGARTCLGQGF 1468 +H DP+ + P+ ++F P RF + + Q ++LPFG G R C+G F Sbjct: 404 IHHDPEFY-PEPEKFIPERFDEDQVQQRPACTFLPFGDGPRNCIGLRF 450
>P15539:C11B2_MOUSE Cytochrome P450 11B2, mitochondrial precursor - Mus musculus (Mouse)| Length = 500 Score = 89.0 bits (219), Expect = 6e-17 Identities = 95/397 (23%), Positives = 174/397 (43%), Gaps = 26/397 (6%) Frame = +2 Query: 368 KEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLK--ATHEPLFG--RGILK 535 +E GP+F +S+G + V P+ ++ S+ L + +L+ H L G RG+ Sbjct: 73 RELGPIFRHSVGKTQIVSVMLPEDAEKLHQVESM-LPRRMHLEPWVAHRELRGLRRGVFL 131 Query: 536 SNGEAWAHQR-----KIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARV-DKSGGTVDIK 697 NG W R +++P+ + K MVD++ A+ LE + +V + G++ + Sbjct: 132 LNGPEWRLNRLRLNRNVLSPKA-VQKFVPMVDMV---ARDFLETLKEKVLQNARGSLTMD 187 Query: 698 IDDDIRAYSADVISRTCFGSSY--------VKGKKIFLKLRELQKAVSK----PNVLAEM 841 + + Y+ + + FG K L + K+ S+ P L Sbjct: 188 VQQSLFNYTIEASNFALFGERLGLLGHDLSPGSLKFIHALHSMFKSTSQLLFLPKSLTRW 247 Query: 842 TGLRFFPTKKNRQAWG-LHKQVHRLILEIVKES--GEDKNLLRAILHSASSSKVGLGEAE 1012 T R + K++ AW + + +R I ++ +E G + + S + L Sbjct: 248 TSTRVW--KEHFDAWDVISEYANRCIWKVHQELRLGSSQTYSGIVAELISQGSLPL---- 301 Query: 1013 NFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGRPLDSQ-SLQK 1189 + I N + ++TA+ L L +P+ Q +RQE L + Q ++ Sbjct: 302 DAIKANSMELTAGSVDTTAIPLVMTLFELARNPDVQKALRQESLAAEASIAANPQKAMSD 361 Query: 1190 MKNLTMVIQETLRLYPAGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWGPDA 1369 + L ++ETLRLYP G F+ R+ +L L H+P G + + + +M +P ++ P Sbjct: 362 LPLLKAALKETLRLYPVGGFLGRILSSDLVLQNYHVPAGTLVLLYLYSMGRNPAVF-PRP 420 Query: 1370 KEFNPARFSDARPQLHSYLPFGAGARTCLGQGFATAE 1480 + + P R+ + R + +L FG G R CLG+ A E Sbjct: 421 ERYMPQRWLE-RKRSFQHLAFGFGVRQCLGRRLAEVE 456
>A2Z212:ABAH3_ORYSI Abscisic acid 8'-hydroxylase 3 - Oryza sativa subsp. indica (Rice)| Length = 500 Score = 89.0 bits (219), Expect = 6e-17 Identities = 89/389 (22%), Positives = 164/389 (42%), Gaps = 12/389 (3%) Frame = +2 Query: 350 FYEKWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRGI 529 F+ +K +G +F + + ++ P+ R + L L K +Y ++ + + Sbjct: 68 FFASKQKRYGEIFKTHILGCPCVMLASPEAARFV-LVTQAHLFKPTYPRSKERMIGPSAL 126 Query: 530 LKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDD 709 + G+ RK++ D ++ +V + + ++ L W+ V + + Sbjct: 127 FFNQGDYHLRLRKLVQGPLGPDALRALVPDVEAAVRSTLASWDGNVSSTFHAM------- 179 Query: 710 IRAYSADVISRTCFGSSYVKGKKIFLKLRELQKAVSKPNVLAEMTGLRFFPTK----KNR 877 + S DV T FG +L E +KA + N G FP Sbjct: 180 -KRLSFDVGIVTIFGG----------RLDERRKAELRQNYAIVEKGYNSFPNSFPGTLYY 228 Query: 878 QAWGLHKQVHRLILEIVKES---GEDKNLLRAILHSASSSKVGLGEAENFIVDNCKSIYF 1048 +A +++H ++ +I++E GE + L L + + G + + DN + F Sbjct: 229 KAIQARRRLHGVLSDIMRERRARGEPGSDLLGCLMQSRAGDDGALLTDEQVADNIIGVLF 288 Query: 1049 AGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEV----CGGR-PLDSQSLQKMKNLTMVI 1213 A ++TA W + L HP+ + VR E + GGR PL + M VI Sbjct: 289 AAQDTTASVLTWIVKYLHDHPKLLEAVRAEQAAIRAANDGGRLPLTWAQTRSMALTHKVI 348 Query: 1214 QETLRLYPAGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARF 1393 E+LR+ +F R A+ +++ G IPKG + +H +P + D ++F+P+RF Sbjct: 349 LESLRMASIISFTFREAVADVEYKGFLIPKGWKVMPLFRNIHHNPDYF-QDPQKFDPSRF 407 Query: 1394 SDARPQLHSYLPFGAGARTCLGQGFATAE 1480 P+ ++++PFG G C G A E Sbjct: 408 K-VSPRPNTFMPFGNGVHACPGNELAKLE 435
>Q9Y758:CP52M_DEBHA Cytochrome P450 52A13 - Debaryomyces hansenii (Yeast) (Torulaspora| hansenii) Length = 519 Score = 88.6 bits (218), Expect = 8e-17 Identities = 94/369 (25%), Positives = 147/369 (39%), Gaps = 41/369 (11%) Frame = +2 Query: 497 ATHEPLFGRGILKSNGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKS 676 A +PL G GI +G W R ++ P+F ++V + LEP R+ K Sbjct: 124 AHFKPLLGDGIFTLDGNGWKQSRSMLRPQFSREQVAHV---------QALEPHLQRLAKH 174 Query: 677 GGTVD---IKIDDDIRAYSADVISRTCFGSSYVKGKKIFLKLRELQKAVSKP------NV 829 D I I D + D + FG S K + + + N Sbjct: 175 IRLADGETINIQDLFFKLTVDTATEFLFGQSVYSLKDAAINDPPTEDFDGRSSFANSFNT 234 Query: 830 LAEMTGLR-----FFPTKKNRQAWGLHKQVHRLI-------LEIVKESGEDKN-----LL 958 G R F+ N KQVH L++ E E K+ L Sbjct: 235 AQTYLGTRAYLQMFYFIVNNSDFRKCCKQVHDFTRFYVQKGLDMTPEELEKKSENGYVFL 294 Query: 959 RAILHSASSSKVGLGEAENFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQE 1138 ++ KV + D +I AG ++TA ++ L HP +++++E Sbjct: 295 YELVKQTRDPKV--------LQDQLLNILLAGRDTTAGLLSFTFFELARHPRVFNKLKEE 346 Query: 1139 VLEVCGG------RPLDSQSLQKMKNLTMVIQETLRLYPAGAFVSRMALQELKL---GG- 1288 + E G + +SL+K + L V+ E LRLYP+ R+A + L GG Sbjct: 347 IYEAFGKGDDARVSEITFESLKKCEYLKWVMNEMLRLYPSVPVNFRVATKRTTLPRGGGP 406 Query: 1289 -----VHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPARFSDARPQLHSYLPFGAGARTC 1453 +++ KG + V + H + +G DA EF P R++++R +Y+PF G R C Sbjct: 407 DGNSPIYVGKGTTVAYSVYSTHRMEEYYGKDADEFKPERWAESRKLGWAYVPFNGGPRIC 466 Query: 1454 LGQGFATAE 1480 LGQ FA E Sbjct: 467 LGQQFALTE 475
>P11715:CP17A_RAT Cytochrome P450 17A1 - Rattus norvegicus (Rat)| Length = 507 Score = 88.6 bits (218), Expect = 8e-17 Identities = 100/448 (22%), Positives = 189/448 (42%), Gaps = 34/448 (7%) Frame = +2 Query: 359 KWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDL-GKSSYLKATHEPLFGRGILK 535 K ++++GP+++ +G + + + R++ + + G+ + + G+G+ Sbjct: 55 KLQEKYGPIYSLRLGTTTTVIIGHYQLAREVLIKKGKEFSGRPQMVTQSLLSDQGKGVAF 114 Query: 536 SN-GEAWAHQRKIIAPEFFLDKVKGMVD-LMVDSAQTLLEPWEARVDKSGGTVDIKIDDD 709 ++ G +W RK++ F L K ++ L+ A++L + A +S I + Sbjct: 115 ADAGSSWHLHRKLVFSTFSLFKDGQKLEKLICQEAKSLCDMMLAHDKES-----IDLSTP 169 Query: 710 IRAYSADVISRTCFGSSYVKGKKIFLKLRELQK----AVSKPNVLAEMTGLRFFPTKKNR 877 I ++I CF SY K ++ + A N++ L FP K Sbjct: 170 IFMSVTNIICAICFNISYEKNDPKLTAIKTFTEGIVDATGDRNLVDIFPWLTIFPNKGLE 229 Query: 878 QAWGLHKQVHRLILEIVKESGEDKN----------LLRAILHSASSSKVGLGEAENF--- 1018 G K + ++ I ++ E + L++A ++S +++ + + F Sbjct: 230 VIKGYAKVRNEVLTGIFEKCREKFDSQSISSLTDILIQAKMNSDNNNSCEGRDPDVFSDR 289 Query: 1019 -IVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCG-GRPLDSQSLQKM 1192 I+ I+ AG E+T W L L +PE + ++++E+ + G R + Sbjct: 290 HILATVGDIFGAGIETTTTVLKWILAFLVHNPEVKKKIQKEIDQYVGFSRTPTFNDRSHL 349 Query: 1193 KNLTMVIQETLRLYP-AGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWG-PD 1366 L I+E LR+ P A + A + +G +PK ++ + + +H D W PD Sbjct: 350 LMLEATIREVLRIRPVAPMLIPHKANVDSSIGEFTVPKDTHVVVNLWALHHDENEWDQPD 409 Query: 1367 AKEFNPARFSDARPQ-----LHSYLPFGAGARTCLGQGFATAEXXXXXXXXXXXFALRLS 1531 +F P RF D SYLPFGAG R+C+G+ A E F L +S Sbjct: 410 --QFMPERFLDPTGSHLITPTQSYLPFGAGPRSCIGEALARQELFVFTALLLQRFDLDVS 467 Query: 1532 -----PLYQHSPALKLIVEPEFGVDITL 1600 P + P + +++P F V IT+ Sbjct: 468 DDKQLPRLEGDPKVVFLIDP-FKVKITV 494
>O81974:C71D8_SOYBN Cytochrome P450 71D8 - Glycine max (Soybean)| Length = 504 Score = 88.6 bits (218), Expect = 8e-17 Identities = 83/399 (20%), Positives = 171/399 (42%), Gaps = 25/399 (6%) Frame = +2 Query: 356 EKWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRGILK 535 +K +++GP+ +G + L VS P + ++ + + L A ++G + Sbjct: 61 QKLVRKYGPLMHLQLGEISTLVVSSPKMAMEMMKTHDVHFVQRPQLLAPQFMVYGATDIA 120 Query: 536 --SNGEAWAHQRKIIAPEFFLDK-VKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDD 706 G+ W RKI E K V+ + D + L++ + S G+ I + Sbjct: 121 FAPYGDYWRQIRKICTLELLSAKRVQSFSHIRQDENKKLIQS----IHSSAGS-PIDLSG 175 Query: 707 DIRAYSADVISRTCFGSSYVKGKKIFLKLRE---LQKAVSKPNVLAEMTGLRFFPTKKNR 877 + + +SR FG + +R+ + ++ + L T++ Sbjct: 176 KLFSLLGTTVSRAAFGKENDDQDEFMSLVRKAITMTGGFEVDDMFPSLKPLHLL-TRQKA 234 Query: 878 QAWGLHKQVHRLILEIVKE--------------SGEDKNLLRAILHSASSSKVGLGEAEN 1015 + +H++ +++ +I+++ E ++L+ +L S + + Sbjct: 235 KVEHVHQRADKILEDILRKHMEKRTRVKEGNGSEAEQEDLVDVLLRLKESGSLEVPMTME 294 Query: 1016 FIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGRPLDSQS-LQKM 1192 I +I+ AG +++A T W + + +P+ +++ + E+ ++ G+ + ++ L+++ Sbjct: 295 NIKAVIWNIFAAGTDTSASTLEWAMSEMMKNPKVKEKAQAELRQIFKGKEIIRETDLEEL 354 Query: 1193 KNLTMVIQETLRLYPAGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWGPDAK 1372 L VI+ETLRL+P + R + + G IP + I + DP+ W DA Sbjct: 355 SYLKSVIKETLRLHPPSQLIPRECIISTNIDGYEIPIKTKVMINTWAIGRDPQYWS-DAD 413 Query: 1373 EFNPARFSDA----RPQLHSYLPFGAGARTCLGQGFATA 1477 F P RF+D+ + Y+PFGAG R C G F A Sbjct: 414 RFIPERFNDSSIDFKGNSFEYIPFGAGRRMCPGMTFGLA 452
>P30100:C11B3_RAT Cytochrome P450 11B3, mitochondrial precursor - Rattus norvegicus| (Rat) Length = 500 Score = 88.6 bits (218), Expect = 8e-17 Identities = 91/391 (23%), Positives = 173/391 (44%), Gaps = 20/391 (5%) Frame = +2 Query: 368 KEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLK--ATHEPLFG--RGILK 535 +E GP+F +S G + V P+ ++ S+ L + +L+ H L G RG+ Sbjct: 73 QELGPIFRHSAGGAQIVSVMLPEDAEKLHQVESI-LPRRMHLEPWVAHRELRGLRRGVFL 131 Query: 536 SNGEAWAHQRKIIAPEFFLDK-VKGMVDLMVDSAQTLLEPWEARVDKSG-GTVDIKIDDD 709 NG W R + P K V+ V ++ + A+ LE + +V ++ G++ + + Sbjct: 132 LNGAEWRFNRLKLNPNVLSPKAVQNFVPMVDEVARDFLEALKKKVRQNARGSLTMDVQQS 191 Query: 710 IRAYSADVISRTCFGSSY--------VKGKKIFLKLRELQKAVSK----PNVLAEMTGLR 853 + Y+ + + FG K L + K+ ++ P L T + Sbjct: 192 LFNYTIEASNFALFGERLGLLGHDLNPGSLKFIHALHSMFKSTTQLLFLPRSLTRWTSTQ 251 Query: 854 FFPTKKNRQAWG-LHKQVHRLILEIVKESGEDKNLLRAILHSASSSKVGLGEAENFIVDN 1030 + K++ AW + + +R I ++ +E + + + +A ++ L + I N Sbjct: 252 VW--KEHFDAWDVISEYANRCIWKVHQELRLGSSQTYSGIVAALITQGAL--PLDAIKAN 307 Query: 1031 CKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGRPLDSQ-SLQKMKNLTM 1207 + ++TA+ L L +P+ Q +RQE L + Q ++ + L Sbjct: 308 SMKLTAGSVDTTAIPLVMTLFELARNPDVQQALRQETLAAEASIAANPQKAMSDLPLLRA 367 Query: 1208 VIQETLRLYPAGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPA 1387 ++ETLRLYP G F+ R+ +L L H+P G + + + +M +P ++ P + + P Sbjct: 368 ALKETLRLYPVGGFLERILNSDLVLQNYHVPAGTLVLLYLYSMGRNPAVF-PRPERYMPQ 426 Query: 1388 RFSDARPQLHSYLPFGAGARTCLGQGFATAE 1480 R+ + R + +L FG G R CLG+ A E Sbjct: 427 RWLE-RKRSFQHLAFGFGVRQCLGRRLAEVE 456
>P30099:C11B2_RAT Cytochrome P450 11B2, mitochondrial precursor - Rattus norvegicus| (Rat) Length = 510 Score = 88.6 bits (218), Expect = 8e-17 Identities = 91/391 (23%), Positives = 173/391 (44%), Gaps = 20/391 (5%) Frame = +2 Query: 368 KEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLK--ATHEPLFG--RGILK 535 +E GP+F +S G + V P+ ++ S+ L + +L+ H L G RG+ Sbjct: 83 QELGPIFRHSAGGAQIVSVMLPEDAEKLHQVESI-LPRRMHLEPWVAHRELRGLRRGVFL 141 Query: 536 SNGEAWAHQRKIIAPEFFLDK-VKGMVDLMVDSAQTLLEPWEARVDKSG-GTVDIKIDDD 709 NG W R + P K V+ V ++ + A+ LE + +V ++ G++ + + Sbjct: 142 LNGAEWRFNRLKLNPNVLSPKAVQNFVPMVDEVARDFLEALKKKVRQNARGSLTMDVQQS 201 Query: 710 IRAYSADVISRTCFGSSY--------VKGKKIFLKLRELQKAVSK----PNVLAEMTGLR 853 + Y+ + + FG K L + K+ ++ P L T + Sbjct: 202 LFNYTIEASNFALFGERLGLLGHDLNPGSLKFIHALHSMFKSTTQLLFLPRSLTRWTSTQ 261 Query: 854 FFPTKKNRQAWG-LHKQVHRLILEIVKESGEDKNLLRAILHSASSSKVGLGEAENFIVDN 1030 + K++ AW + + +R I ++ +E + + + +A ++ L + I N Sbjct: 262 VW--KEHFDAWDVISEYANRCIWKVHQELRLGSSQTYSGIVAALITQGAL--PLDAIKAN 317 Query: 1031 CKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGRPLDSQ-SLQKMKNLTM 1207 + ++TA+ L L +P+ Q +RQE L + Q ++ + L Sbjct: 318 SMELTAGSVDTTAIPLVMTLFELARNPDVQQALRQETLAAEASIAANPQKAMSDLPLLRA 377 Query: 1208 VIQETLRLYPAGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWGPDAKEFNPA 1387 ++ETLRLYP G F+ R+ +L L H+P G + + + +M +P ++ P + + P Sbjct: 378 ALKETLRLYPVGGFLERILNSDLVLQNYHVPAGTLVLLYLYSMGRNPAVF-PRPERYMPQ 436 Query: 1388 RFSDARPQLHSYLPFGAGARTCLGQGFATAE 1480 R+ + R + +L FG G R CLG+ A E Sbjct: 437 RWLE-RKRSFQHLAFGFGVRQCLGRRLAEVE 466
>P37115:TCMO_PHAAU Trans-cinnamate 4-monooxygenase - Phaseolus aureus (Mung bean) (Vigna| radiata) Length = 505 Score = 88.2 bits (217), Expect = 1e-16 Identities = 109/405 (26%), Positives = 161/405 (39%), Gaps = 41/405 (10%) Frame = +2 Query: 368 KEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLGKSSYLKATHEPLFGRG---ILKS 538 K G +F MG + VS PD+ +++ ++ G S + G G + Sbjct: 63 KRFGDIFLLRMGQRNLVVVSSPDLAKEVLHTQGVEFG-SRTRNVVFDIFTGEGQDMVFTV 121 Query: 539 NGEAWAHQRKIIAPEFFLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRA 718 GE W R+I+ FF +KV Q WEA ++ VD + A Sbjct: 122 YGEHWRKMRRIMTVPFFTNKV----------VQQYRHGWEA---EAAAVVDDVRKNPDAA 168 Query: 719 YSADVISRTCFGSSYVKGKKI-------------FLKLRELQKAVSKPNVLAEMTGLRFF 859 S VI R Y +I F +L+ L S+ E F Sbjct: 169 VSGLVIRRRLQLMMYNNMYRIMFDRRFESEEDPLFQRLKALNGERSRLAQSFEYNYGDFI 228 Query: 860 PTKKN--RQAWGLHKQVHRLILEIVKE-------------SGEDKNLLRAILHSASSSKV 994 P + + + K+V L++ K+ S ++ L AI H + K Sbjct: 229 PILRPFLKGYLKICKEVKETRLKLFKDYFVDERKNIGSTKSTNNEGLKCAIDHILDAEKK 288 Query: 995 GLGEAEN--FIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCG-GRP 1165 G +N +IV+N I A E+T + W + L HPE Q +VR E+ V G G Sbjct: 289 GEINEDNVLYIVEN---INVAAIETTLWSIEWGIAELVNHPEIQQKVRDEIDRVLGVGHQ 345 Query: 1166 LDSQSLQKMKNLTMVIQETLRLYPA-GAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHL 1342 + +QK+ L V++ETLRL A V M L + KLGG IP I + + Sbjct: 346 VTEPDIQKLPYLQAVVKETLRLRMAIPLLVPHMNLHDAKLGGYDIPAESKILVNAWWLAN 405 Query: 1343 DPKLWGPDAKEFNPARFSDARPQLHS------YLPFGAGARTCLG 1459 +P W +EF P RF + + + YLPFG G R+C G Sbjct: 406 NPAHW-KKPEEFRPERFFEEESHVEANGNDFRYLPFGVGRRSCPG 449
>P05093:CP17A_HUMAN Cytochrome P450 17A1 - Homo sapiens (Human)| Length = 508 Score = 88.2 bits (217), Expect = 1e-16 Identities = 108/448 (24%), Positives = 189/448 (42%), Gaps = 30/448 (6%) Frame = +2 Query: 359 KWRKEHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDL-GKSSYLKATHEPLFGRGI-L 532 K +K++GP+++ MG + V + +++ + D G+ +GI Sbjct: 55 KLQKKYGPIYSVRMGTKTTVIVGHHQLAKEVLIKKGKDFSGRPQMATLDIASNNRKGIAF 114 Query: 533 KSNGEAWAHQRKIIAPEF--FLDKVKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDD 706 +G W R++ F F D + + ++ TL + +G ++DI Sbjct: 115 ADSGAHWQLHRRLAMATFALFKDGDQKLEKIICQEISTLCDMLATH---NGQSIDISFPV 171 Query: 707 DIRAYSADVISRTCFGSSYVKGKKIFLKLRELQKAV----SKPNVLAEMTGLRFFPTK-- 868 + +VIS CF +SY G ++ + + SK +++ + L+ FP K Sbjct: 172 FVAV--TNVISLICFNTSYKNGDPELNVIQNYNEGIIDNLSKDSLVDLVPWLKIFPNKTL 229 Query: 869 -KNRQAWGLHKQVHRLILEIVKE---SGEDKNLLRAILHSASSSKVGLGE--------AE 1012 K + + + ILE KE S N+L ++ + +S G ++ Sbjct: 230 EKLKSHVKIRNDLLNKILENYKEKFRSDSITNMLDTLMQAKMNSDNGNAGPDQDSELLSD 289 Query: 1013 NFIVDNCKSIYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCG-GRPLDSQSLQK 1189 N I+ I+ AG E+T W L L +P+ + ++ +E+ + G R + Sbjct: 290 NHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTPTISDRNR 349 Query: 1190 MKNLTMVIQETLRLYP-AGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWG-P 1363 + L I+E LRL P A + A + +G + KG + I + +H + K W P Sbjct: 350 LLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQP 409 Query: 1364 DAKEFNPARF-SDARPQLHS----YLPFGAGARTCLGQGFATAEXXXXXXXXXXXFALRL 1528 D +F P RF + A QL S YLPFGAG R+C+G+ A E F L + Sbjct: 410 D--QFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRFDLEV 467 Query: 1529 SPLYQHSPALKLIVEPEFGVDITLTKVQ 1612 P P+L+ I + F +D K++ Sbjct: 468 -PDDGQLPSLEGIPKVVFLIDSFKVKIK 494
>O48923:C71DA_SOYBN Cytochrome P450 71D10 - Glycine max (Soybean)| Length = 510 Score = 88.2 bits (217), Expect = 1e-16 Identities = 92/397 (23%), Positives = 176/397 (44%), Gaps = 30/397 (7%) Frame = +2 Query: 371 EHGPVFTYSMGNVVFLHVSRPDVVRDINLCVSLDLG-KSSYLKATHEPLFGRGILKS-NG 544 ++GP+ +G V + V+ P++ ++I L+ + ++ + G GI+ S +G Sbjct: 75 KYGPLMHLKLGEVSNIIVTSPEMAQEIMKTHDLNFSDRPDFVLSRIVSYNGSGIVFSQHG 134 Query: 545 EAWAHQRKIIAPEFFLDK-VKGMVDLMVDSAQTLLEPWEARVDKSGGTVDIKIDDDIRAY 721 + W RKI E K V+ + + L++ A + GG++ + I + Sbjct: 135 DYWRQLRKICTVELLTAKRVQSFRSIREEEVAELVKKIAATASEEGGSI-FNLTQSIYSM 193 Query: 722 SADVISRTCFGSSYVKGKKIFLKLRELQKAVSKPNVLAEMTGLRFFPTKKNRQAWG---- 889 + + +R FG + +++F+ Q + +A++ +P+ + Q G Sbjct: 194 TFGIAARAAFGKKS-RYQQVFISNMHKQLMLLGGFSVADL-----YPSSRVFQMMGATGK 247 Query: 890 ---LHKQVHRLILEIVKE------SGEDK----NLLRAILHSASSSKVGLGEAENFIVDN 1030 +H+ R++ +I+ E S E++ +L+ +L S+ L + DN Sbjct: 248 LEKVHRVTDRVLQDIIDEHKNRNRSSEEREAVEDLVDVLLKFQKESEFRLTD------DN 301 Query: 1031 CKS----IYFAGYESTAVTAAWCLMLLGLHPEWQDRVRQEVLEVCGGRP-LDSQSLQKMK 1195 K+ I+ G E+++ W + L +P + + EV V + +D L ++ Sbjct: 302 IKAVIQDIFIGGGETSSSVVEWGMSELIRNPRVMEEAQAEVRRVYDSKGYVDETELHQLI 361 Query: 1196 NLTMVIQETLRLYP-AGAFVSRMALQELKLGGVHIPKGVNIYIPVSTMHLDPKLWGPDAK 1372 L +I+ET+RL+P V R++ + ++ G IP I I + +PK WG + + Sbjct: 362 YLKSIIKETMRLHPPVPLLVPRVSRERCQINGYEIPSKTRIIINAWAIGRNPKYWG-ETE 420 Query: 1373 EFNPARF----SDARPQLHSYLPFGAGARTCLGQGFA 1471 F P RF D R ++PFGAG R C G FA Sbjct: 421 SFKPERFLNSSIDFRGTDFEFIPFGAGRRICPGITFA 457 Database: uniprot_sprot.fasta.out Posted date: Jul 19, 2007 5:58 PM Number of letters in database: 100,686,439 Number of sequences in database: 274,295 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 274295 Number of Hits to DB: 277,258,399 Number of extensions: 5753061 Number of successful extensions: 19734 Number of sequences better than 10.0: 763 Number of HSP's gapped: 18468 Number of HSP's successfully gapped: 859 Length of query: 588 Length of database: 100,686,439 Length adjustment: 119 Effective length of query: 469 Effective length of database: 68,045,334 Effective search space: 31913261646 Effective search space used: 31913261646 Neighboring words threshold: 12 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
