>Q9BV94:EDEM2_HUMAN ER degradation-enhancing alpha-mannosidase-like 2 precursor - Homo|
            sapiens (Human)
          Length = 578
 Score =  402 bits (1034), Expect = e-111
 Identities = 210/460 (45%), Positives = 289/460 (62%), Gaps = 20/460 (4%)
 Frame = +3

Query: 168  DGVTPTEALRLRDEVKDMFYHAFDGYMQHAFPLDELRPLSCQGEDSLGGYALTLIDSLDT 347
            DG  P  A   R+ VK MFYHA+D Y+++AFP DELRPL+C G D+ G ++LTLID+LDT
Sbjct: 26   DGSAPDPA-HYRERVKAMFYHAYDSYLENAFPFDELRPLTCDGHDTWGSFSLTLIDALDT 84

Query: 348  LALLGDKERFAAGVEWVGKNVRFDINKTVSVFETNIRILGGLLSAHLIASDYATGMKIES 527
            L +LG+   F   VE +  +V FDI+   SVFETNIR++GGLLSAHL++     G+++E+
Sbjct: 85   LLILGNVSEFQRVVEVLQDSVDFDIDVNASVFETNIRVVGGLLSAHLLSKK--AGVEVEA 142

Query: 528  ---YXXXXXXXXXXXXXXXXPAFDTPTGIPFGSVNLLYGVDDDESKITSTAGGGTLTLEF 698
                                PAF TPTG+P+G+VNLL+GV+  E+ +T TAG GT  +EF
Sbjct: 143  GWPCSGPLLRMAEEAARKLLPAFQTPTGMPYGTVNLLHGVNPGETPVTCTAGIGTFIVEF 202

Query: 699  GVLSRLTNNTVFEQVTKNSVRGIWARRSKLNLVGAHINVFTGEWTQKDAGIGTSIDSFYE 878
              LS LT + VFE V + ++  +W  RS + LVG HI+V TG+W  +DAGIG  +DS++E
Sbjct: 203  ATLSSLTGDPVFEDVARVALMRLWESRSDIGLVGNHIDVLTGKWVAQDAGIGAGVDSYFE 262

Query: 879  YLLKAYLLFGDEEYLYVFEEAYKAAMHYLHHDPWYIEVNMNSGATVWPLFNSLQAFWPGL 1058
            YL+K  +L  D++ + +F E  KA  +Y   D WY+ V M  G    P+F SL+A+WPGL
Sbjct: 263  YLVKGAILLQDKKLMAMFLEYNKAIRNYTRFDDWYLWVQMYKGTVSMPVFQSLEAYWPGL 322

Query: 1059 QVLAGDVDPAIRTHAAFFSVWKKYGFTPEGFNLATSTVQNGQRSYPLRPELIESTYWLFK 1238
            Q L GD+D A+RT   +++VWK++G  PE +N+        +  YPLRPELIES  +L++
Sbjct: 323  QSLIGDIDNAMRTFLNYYTVWKQFGGLPEFYNIPQGYTVEKREGYPLRPELIESAMYLYR 382

Query: 1239 ATRDFRYLDVGRDILASLQYAAKCPCGYCHISDVETHKQDDHMESFFLAETVKYLWLLFD 1418
            AT D   L++GRD + S++  +K  CG+  I D+  HK D+ MESFFLAETVKYL+LLFD
Sbjct: 383  ATGDPTLLELGRDAVESIEKISKVECGFATIKDLRDHKLDNRMESFFLAETVKYLYLLFD 442

Query: 1419 LAVGPDNIVENG---------PY--------KYIFSTEGH 1487
                P N + N          PY         YIF+TE H
Sbjct: 443  ----PTNFIHNNGSTFDAVITPYGECILGAGGYIFNTEAH 478

>Q92611:EDEM1_HUMAN ER degradation-enhancing alpha-mannosidase-like 1 - Homo sapiens|
            (Human)
          Length = 657

 Score =  365 bits (938), Expect = e-100
 Identities = 209/479 (43%), Positives = 278/479 (58%), Gaps = 29/479 (6%)
 Frame = +3

Query: 180  PTEALRLRDEVKDMFYHAFDGYMQHAFPLDELRPLSCQGE-------------DSLGGYA 320
            P    ++RD  + MF   +D YM HAFP DEL P+ C+G              D LG Y+
Sbjct: 124  PQLRAQMRDLARGMFVFGYDNYMAHAFPQDELNPIHCRGRGPDRGDPSNLNINDVLGNYS 183

Query: 321  LTLIDSLDTLALLGDKERFAAGVEWVGKNVRFDINKTVSVFETNIRILGGLLSAHLIASD 500
            LTL+D+LDTLA++G+   F   V+ V   V FD + TV VFE  IR+LG LLSAH I +D
Sbjct: 184  LTLVDALDTLAIMGNSSEFQKAVKLVINTVSFDKDSTVQVFEATIRVLGSLLSAHRIITD 243

Query: 501  YAT---GMKIESYXXXXXXXXXXXXXXXXPAFD-TPTGIPFGSVNLLYGVDDDESKITST 668
                   M I+ Y                PAF+ T TGIP+  VNL  GV  D +  T T
Sbjct: 244  SKQPFGDMTIKDYDNELLYMAHDLAVRLLPAFENTKTGIPYPRVNLKTGVPPDTNNETCT 303

Query: 669  AGGGTLTLEFGVLSRLTNNTVFEQVTKNSVRGIWARRSK-LNLVGAHINVFTGEWTQKDA 845
            AG G+L +EFG+LSRL  ++ FE V + +V+ +W  RS    L+G  +N+ TG W  K +
Sbjct: 304  AGAGSLLVEFGILSRLLGDSTFEWVARRAVKALWNLRSNDTGLLGNVVNIQTGHWVGKQS 363

Query: 846  GIGTSIDSFYEYLLKAYLLFGDEEYLYVFEEAYKAAMHYLHHD-----------PWYIEV 992
            G+G  +DSFYEYLLK+Y+LFG++E L +F  AY++  +YL              P Y+ V
Sbjct: 364  GLGAGLDSFYEYLLKSYILFGEKEDLEMFNAAYQSIQNYLRRGREACNEGEGDPPLYVNV 423

Query: 993  NMNSGATVWPLFNSLQAFWPGLQVLAGDVDPAIRTHAAFFSVWKKYGFTPEGFNLATSTV 1172
            NM SG  +    +SLQAF+PGLQVL GDV+ AI  HA ++++WK+YG  PE +N      
Sbjct: 424  NMFSGQLMNTWIDSLQAFFPGLQVLIGDVEDAICLHAFYYAIWKRYGALPERYNWQLQAP 483

Query: 1173 QNGQRSYPLRPELIESTYWLFKATRDFRYLDVGRDILASLQYAAKCPCGYCHISDVETHK 1352
                  YPLRPEL+ESTY L++AT++  YL VG DIL SL+   K  CGY  +  V    
Sbjct: 484  D--VLFYPLRPELVESTYLLYQATKNPFYLHVGMDILQSLEKYTKVKCGYATLHHVIDKS 541

Query: 1353 QDDHMESFFLAETVKYLWLLFDLAVGPDNIVENGPYKYIFSTEGHLLPATPEISLVDEH 1529
             +D MESFFL+ET KYL+LLFD     DN V     +Y+F+TEGH++        VDEH
Sbjct: 542  TEDRMESFFLSETCKYLYLLFD----EDNPVHKSGTRYMFTTEGHIVS-------VDEH 589

>Q925U4:EDEM1_MOUSE ER degradation-enhancing alpha-mannosidase-like 1 - Mus musculus|
            (Mouse)
          Length = 652

 Score =  364 bits (935), Expect = e-100
 Identities = 205/467 (43%), Positives = 274/467 (58%), Gaps = 29/467 (6%)
 Frame = +3

Query: 180  PTEALRLRDEVKDMFYHAFDGYMQHAFPLDELRPLSCQGE-------------DSLGGYA 320
            P    ++RD  + MF   +D YM HAFP DEL P+ C+G              D LG Y+
Sbjct: 119  PQLRAQMRDLARGMFVFGYDNYMAHAFPQDELNPIYCRGRGPDRGDPSNLNINDVLGNYS 178

Query: 321  LTLIDSLDTLALLGDKERFAAGVEWVGKNVRFDINKTVSVFETNIRILGGLLSAHLIASD 500
            LTL+D+LDTLA++G+   F   V+ V   V FD + TV VFE  IR+LG LLSAH I +D
Sbjct: 179  LTLVDALDTLAIMGNSSEFQKAVKLVINTVSFDKDSTVQVFEATIRVLGSLLSAHRIITD 238

Query: 501  YAT---GMKIESYXXXXXXXXXXXXXXXXPAFD-TPTGIPFGSVNLLYGVDDDESKITST 668
                   M IE Y                PAF+ T TGIP+  VNL  GV  D +  T T
Sbjct: 239  SKQPFGDMTIEDYDNELLYMAHDLAVRLLPAFENTKTGIPYPRVNLKTGVPPDSNNETCT 298

Query: 669  AGGGTLTLEFGVLSRLTNNTVFEQVTKNSVRGIWARRSK-LNLVGAHINVFTGEWTQKDA 845
            AG G+L +EFG+LSRL  ++ FE V + +V+ +W  RS    L+G  +N+ TG W  K +
Sbjct: 299  AGAGSLLVEFGILSRLLGDSTFEWVARRAVKALWNLRSNDTGLLGNVVNIQTGHWVGKQS 358

Query: 846  GIGTSIDSFYEYLLKAYLLFGDEEYLYVFEEAYKAAMHYLHHD-----------PWYIEV 992
            G+G  +DSFYEYLLK+Y+LFG++E L +F  AY++   YL              P Y+ V
Sbjct: 359  GLGAGLDSFYEYLLKSYILFGEKEDLEMFNAAYQSIQSYLRRGREACNEGEGDPPLYVNV 418

Query: 993  NMNSGATVWPLFNSLQAFWPGLQVLAGDVDPAIRTHAAFFSVWKKYGFTPEGFNLATSTV 1172
            NM SG  +    +SLQAF+PGLQVL GDV+ AI  HA ++++WK+YG  PE +N      
Sbjct: 419  NMFSGQLMNTWIDSLQAFFPGLQVLIGDVEDAICLHAFYYAIWKRYGALPERYNWQLQAP 478

Query: 1173 QNGQRSYPLRPELIESTYWLFKATRDFRYLDVGRDILASLQYAAKCPCGYCHISDVETHK 1352
                  YPLRPEL+ESTY L++AT++  YL VG DIL SL+   K  CGY  +  V    
Sbjct: 479  D--VLFYPLRPELVESTYLLYQATKNPFYLHVGMDILQSLEKYTKVKCGYATLHHVIDKS 536

Query: 1353 QDDHMESFFLAETVKYLWLLFDLAVGPDNIVENGPYKYIFSTEGHLL 1493
            ++D MESFFL+ET KYL+LLFD     +N V     +Y+F+TEGH++
Sbjct: 537  KEDRMESFFLSETCKYLYLLFD----EENPVHKSGTRYMFTTEGHII 579

>Q9BZQ6:EDEM3_HUMAN ER degradation-enhancing alpha-mannosidase-like 3 - Homo sapiens|
            (Human)
          Length = 889

 Score =  347 bits (890), Expect = 1e-94
 Identities = 197/459 (42%), Positives = 275/459 (59%), Gaps = 22/459 (4%)
 Frame = +3

Query: 186  EALRLRDEVKDMFYHAFDGYMQHAFPLDELRPLSCQG------------EDSLGGYALTL 329
            E  +L ++V +MF HA+  YM+HA+P DEL PL+C+G            +D+LG ++LTL
Sbjct: 5    EKQKLGNQVLEMFDHAYGNYMEHAYPADELMPLTCRGRVRGQEPSRGDVDDALGKFSLTL 64

Query: 330  IDSLDTLALLGDKERFAAGVEWVGKNVRFDINKTVSVFETNIRILGGLLSAHLIASDYAT 509
            IDSLDTL +L   + F   V  V ++V  D +  VSVFETNIR+LGGLL  H +A     
Sbjct: 65   IDSLDTLVVLNKTKEFEDAVRKVLRDVNLDNDVVVSVFETNIRVLGGLLGGHSLAIMLKE 124

Query: 510  -GMKIESYXXXXXXXXXXXXXXXXPAFDTPTGIPFGSVNLLYGVDDDESKI-----TSTA 671
             G  ++ Y                PAF+T +G+P+  +NL +G+   E++      T TA
Sbjct: 125  KGEYMQWYNDELLQMAKQLGYKLLPAFNTTSGLPYPRINLKFGIRKPEARTGTETDTCTA 184

Query: 672  GGGTLTLEFGVLSRLTNNTVFEQVTKNSVRGIWARRSKL-NLVGAHINVFTGEWTQKDAG 848
              GTL LEF  LSR T  T+FE+  + ++  +W +R +  NLVG  IN+ TG+W +KD+G
Sbjct: 185  CAGTLILEFAALSRFTGATIFEEYARKALDFLWEKRQRSSNLVGVTINIHTGDWVRKDSG 244

Query: 849  IGTSIDSFYEYLLKAYLLFGDEEYLYVFEEAYKAAMHYLHHDPWYIEVNMNS---GATVW 1019
            +G  IDS+YEYLLKAY+L GD+ +L  F   Y A M Y+   P  ++V+++     A  W
Sbjct: 245  VGAGIDSYYEYLLKAYVLLGDDSFLERFNTHYDAIMRYISQPPLLLDVHIHKPMLNARTW 304

Query: 1020 PLFNSLQAFWPGLQVLAGDVDPAIRTHAAFFSVWKKYGFTPEGFNLATSTVQNGQRSYPL 1199
               ++L AF+PGLQVL GD+ PAI TH   + V KK+ F PE F   T+  +     +PL
Sbjct: 305  --MDALLAFFPGLQVLKGDIRPAIETHEMLYQVIKKHNFLPEAF---TTDFRVHWAQHPL 359

Query: 1200 RPELIESTYWLFKATRDFRYLDVGRDILASLQYAAKCPCGYCHISDVETHKQDDHMESFF 1379
            RPE  ESTY+L+KAT D  YL+VG+ ++ +L   A+ PCG+  + DV T   +D M+SFF
Sbjct: 360  RPEFAESTYFLYKATGDPYYLEVGKTLIENLNKYARVPCGFAAMKDVRTGSHEDRMDSFF 419

Query: 1380 LAETVKYLWLLFDLAVGPDNIVENGPYKYIFSTEGHLLP 1496
            LAE  KYL+LLF  A   D I +     YIF+TE HLLP
Sbjct: 420  LAEMFKYLYLLF--ADKEDIIFD--IEDYIFTTEAHLLP 454

>P38888:YH04_YEAST Uncharacterized glycosyl hydrolase YHR204W precursor - Saccharomyces|
            cerevisiae (Baker's yeast)
          Length = 796

 Score =  264 bits (675), Expect = 1e-69
 Identities = 169/475 (35%), Positives = 246/475 (51%), Gaps = 38/475 (8%)
 Frame = +3

Query: 177  TPTEALRLRDEVKDMFYHAFDGYMQHAFPLDELRPLSC------------QG-EDSLGGY 317
            T  E    + EVK++FY  FD Y++H +P DE++P+SC            QG  D LG +
Sbjct: 28   TSKELKAYKQEVKELFYFGFDNYLEHGYPYDEVKPISCVPKKRNFEDPTDQGTNDILGNF 87

Query: 318  ALTLIDSLDTLALLGDKERFAAGVEWVGKNV---RFDINKTVSVFETNIRILGGLLSAHL 488
             +TLIDSL T+A+L D+ +F   V  V +      FDI+ T+ VFE  IR++G LLS+HL
Sbjct: 88   TITLIDSLTTIAILEDRPQFLKAVRLVERTFPDGNFDIDSTIQVFEITIRVIGSLLSSHL 147

Query: 489  IASDYATGMKI-ESYXXXXXXXXXXXXXXXXPAFDTPTGIPFGSVNLLYGVDDDE----- 650
             A+D    + + + Y                PA+ T TG+P    N+    D  E     
Sbjct: 148  YATDPTKAVYLGDDYDGSLLRLAQNMADRLLPAYLTSTGLPMPRRNIKRKWDVSEFPEFL 207

Query: 651  SKITSTAGGGTLTLEFGVLSRLTNNTVFEQVTKNSVRGIWARRSKLNLVGAHINVFTGEW 830
                + A   +   EF +LS LT +  +E+VT+ +    W+ R+ L+L+    +      
Sbjct: 208  ETENNVAAMASPMFEFTILSYLTGDPKYEKVTRYAFDKTWSLRTGLDLLPMSFHPEKLTP 267

Query: 831  TQKDAGIGTSIDSFYEYLLKAYLLFGDEEYLYVFEEAYKAAMHYLHHDPWYIEVNMNSGA 1010
                 GIG SIDS +EY LK  +LF D E + V+  AY+A      +D ++  V  ++G 
Sbjct: 268  YTPMTGIGASIDSLFEYALKGAILFDDSELMEVWNVAYEALKTNCKNDWFFANVMADTGH 327

Query: 1011 TVWPLFNSLQAFWPGLQVLAGDVDPAIRTHAAFFSVWKKYGFTPEGFNLAT---STVQNG 1181
               P  +SL AF+ GLQVLAGD+D AI  H  F  +W  +G  PE +N +      +   
Sbjct: 328  LFVPWIDSLSAFFSGLQVLAGDLDDAIANHLMFLKMWNTFGGIPERWNFSPPEFPPLSPL 387

Query: 1182 QRS-------------YPLRPELIESTYWLFKATRDFRYLDVGRDILASLQYAAKCPCGY 1322
            +RS             YPLRPE  ESTY+L++AT+D  YL++G  +L  L+   K  CG+
Sbjct: 388  ERSGAVALDNILPLEWYPLRPEFFESTYFLYRATKDPFYLNIGVHLLKDLKQRFKSNCGF 447

Query: 1323 CHISDVETHKQDDHMESFFLAETVKYLWLLFDLAVGPDNIVENGPYKYIFSTEGH 1487
                +V T +  D ME+F L+ET+KYL+LLFD     +N + N     IFSTE H
Sbjct: 448  AGFQNVITGELQDRMETFVLSETLKYLYLLFD----EENELHNSASDVIFSTEAH 498

>P39098:MA1A2_MOUSE Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB - Mus musculus|
            (Mouse)
          Length = 641

 Score =  183 bits (464), Expect = 3e-45
 Identities = 147/478 (30%), Positives = 231/478 (48%), Gaps = 41/478 (8%)
 Frame = +3

Query: 186  EALRLRDEVKDMFYHAFDGYMQHAFPLDELRPLSCQGEDS----LGGYALTLIDSLDTLA 353
            E  + RD++K+M  HA+D Y  + +  +ELRP++ +G  +          T++D+LDTL 
Sbjct: 176  EIKKKRDKIKEMMKHAWDNYRTYGWGHNELRPIARKGHSTNIFGSSQMGATIVDALDTLY 235

Query: 354  LLGDKERFAAGVEWVGKNVRFDINKTVSVFETNIRILGGLLSAHLIASDYATGMKIESYX 533
            ++G  + F  G  W+ +N+ F +N  VSVFE NIR +GGLL+A+     Y +G +I    
Sbjct: 236  IMGLHDEFMDGQRWIEENLDFSVNSEVSVFEVNIRFIGGLLAAY-----YLSGEEI---- 286

Query: 534  XXXXXXXXXXXXXXXPAFDTPTGIPFGSVNLLYGVDDD----ESKITSTAGGGTLTLEFG 701
                           PAF+TPTGIP+  VNL  GV  +     +  +  A  GTL +EF 
Sbjct: 287  --FKTKAVQLAEKLLPAFNTPTGIPWAMVNLKSGVGRNWGWASAGSSILAEFGTLHMEFV 344

Query: 702  VLSRLTNNTVFEQVTKNSVRGIWARRSKLN-LVGAHINVFTGEWTQKDAGIGTSIDSFYE 878
             LS LT +  +     + +R +  +  + N L   ++N  TG W Q    +G   DSFYE
Sbjct: 345  HLSYLTGDLTYYNKVMH-IRKLLQKMERPNGLYPNYLNPRTGRWGQYHTSVGGLGDSFYE 403

Query: 879  YLLKAYLLFG--DEEYLYVFEEAYKAAMHYLHHDPWYIEVNMNSGATVW----------P 1022
            YLLKA+L+    D E   ++++A +A   +L        +  + G  V+           
Sbjct: 404  YLLKAWLMSDKTDHEARRMYDDAVEAIEKHL--------IKKSRGGLVFIGEWKNGHLER 455

Query: 1023 LFNSLQAFWPGLQVLAGD--------------VDPAIRTHAAFFSVWKKYGFTPEGFN-- 1154
                L  F  G+  L  D               + A   H ++     K G  PE F   
Sbjct: 456  KMGHLACFAGGMFALGADGSRKDKAGHYLELGAEIARTCHESYDRTALKLG--PESFKFD 513

Query: 1155 --LATSTVQNGQRSYPLRPELIESTYWLFKATRDFRYLDVGRDILASLQYAAKCPCGYCH 1328
              +    V+  ++ Y LRPE+IE+ ++L++ T D RY   G +   +++ + +   G+  
Sbjct: 514  GAVEAVAVRQAEKYYILRPEVIETYWYLWRFTHDPRYRQWGWEAALAIEKSCRVSGGFSG 573

Query: 1329 ISDV--ETHKQDDHMESFFLAETVKYLWLLFDLAVGPDNIVENGPYKYIFSTEGHLLP 1496
            + DV   T   DD  +SFFLAET+KYL+LLF    G D +  +    ++F+TE H LP
Sbjct: 574  VKDVYAPTPVHDDVQQSFFLAETLKYLYLLFS---GDDLLPLD---HWVFNTEAHPLP 625

>P45701:MA1A1_RABIT Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA - Oryctolagus|
            cuniculus (Rabbit)
          Length = 469

 Score =  183 bits (464), Expect = 3e-45
 Identities = 148/468 (31%), Positives = 234/468 (50%), Gaps = 33/468 (7%)
 Frame = +3

Query: 201  RDEVKDMFYHAFDGYMQHAFPLDELRPLSCQGEDS-LGGY--ALTLIDSLDTLALLGDKE 371
            R ++K+M  HA++ Y ++A+ L+EL+P++ +G  S L G     T++D+LDTL ++G + 
Sbjct: 12   RAKIKEMMEHAWNSYKRYAWGLNELKPITKEGHSSSLFGTIKGATIVDALDTLFIMGMES 71

Query: 372  RFAAGVEWVGKNVRFDINKTVSVFETNIRILGGLLSAHLIASDYATGMKIESYXXXXXXX 551
             F     W+ +N+ F++N  +SVFE NIR +GGLLSA+     Y +G +I          
Sbjct: 72   EFQEAKSWIAENLDFNVNAEISVFEVNIRFVGGLLSAY-----YLSGEEI------FRKK 120

Query: 552  XXXXXXXXXPAFDTPTGIPFGSVNLLYGVDDD----ESKITSTAGGGTLTLEFGVLSRLT 719
                     PAF TP+GIP+  +N+  G+  +        +  A  GTL LEF  LS L+
Sbjct: 121  AVELGIKLLPAFHTPSGIPWALLNIKSGIGRNWPWASGGSSILAEFGTLHLEFMHLSHLS 180

Query: 720  NNTVFEQVTKNSVRGIWARRSKLNLVGAHINVFTGEWTQKDAGIGTSIDSFYEYLLKAYL 899
             N +F +   N  + +        L   ++N  +G+W Q    IG   DSFYEYLLKA+L
Sbjct: 181  GNPIFAEKVMNIRKVLNKLEKPEGLYPNYLNPSSGQWGQHHVSIGGLGDSFYEYLLKAWL 240

Query: 900  LF--GDEEYLYVFEEAYKAAMHYL--HHDPWYIEVNMNSGATVWPLFNSLQAFWPGLQVL 1067
            +    D E   ++ +A +A   +L          +    G  +      L  F  G+  L
Sbjct: 241  MSEKTDLEAKKMYFDAVQAIETHLIRKSSGGLTYIAEWKGGLLEHKMGHLTCFAGGMFAL 300

Query: 1068 AGDVDPAIRT--------------HAAFFSVWKKYGFTPEGFNL-----ATSTVQNGQRS 1190
              D  P  R               H ++   + K G  PE F       A +T QN ++ 
Sbjct: 301  GADGAPEGRAQHYLELGAEIARTCHESYNRTFMKLG--PEAFRFDGGVEAIATRQN-EKY 357

Query: 1191 YPLRPELIESTYWLFKATRDFRYLDVGRDILASLQYAAKCPCGYCHISDVE-TH-KQDDH 1364
            Y LRPE++E+  ++++ T D +Y     + + +L+   +   GY  + DV  TH K D+ 
Sbjct: 358  YILRPEVVETYMYMWRLTHDPKYRKWAWEAVEALESHCRVNGGYSGLRDVYFTHEKYDNV 417

Query: 1365 MESFFLAETVKYLWLLFDLAVGPDNIVENGPYK-YIFSTEGHLLPATP 1505
             +SFFLAET+KYL+L+F      D+++   P + +IF+TE HLLP  P
Sbjct: 418  QQSFFLAETLKYLYLIF----SDDDLL---PLEHWIFNTEAHLLPILP 458

>O60476:MA1A2_HUMAN Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB - Homo sapiens|
            (Human)
          Length = 641

 Score =  178 bits (452), Expect = 8e-44
 Identities = 142/473 (30%), Positives = 226/473 (47%), Gaps = 41/473 (8%)
 Frame = +3

Query: 201  RDEVKDMFYHAFDGYMQHAFPLDELRPLSCQGED----SLGGYALTLIDSLDTLALLGDK 368
            R+++K+M  HA+D Y  + +  +ELRP++ +G             T++D+LDTL ++G  
Sbjct: 181  REKIKEMMKHAWDNYRTYGWGHNELRPIARKGHSPNIFGSSQMGATIVDALDTLYIMGLH 240

Query: 369  ERFAAGVEWVGKNVRFDINKTVSVFETNIRILGGLLSAHLIASDYATGMKIESYXXXXXX 548
            + F  G  W+  N+ F +N  VSVFE NIR +GGLL+A+ ++ +    +K          
Sbjct: 241  DEFLDGQRWIEDNLDFSVNSEVSVFEVNIRFIGGLLAAYYLSGEEIFKIK---------- 290

Query: 549  XXXXXXXXXXPAFDTPTGIPFGSVNLLYGVDDD----ESKITSTAGGGTLTLEFGVLSRL 716
                      PAF+TPTGIP+  VNL  GV  +     +  +  A  GTL +EF  LS L
Sbjct: 291  -AVQLAEKLLPAFNTPTGIPWAMVNLKSGVGRNWGWASAGSSILAEFGTLHMEFIHLSYL 349

Query: 717  TNNTVFEQVTKNSVRGIWARRSKLN-LVGAHINVFTGEWTQKDAGIGTSIDSFYEYLLKA 893
            T +  + +   + +R +  +  + N L   ++N  TG W Q    +G   DSFYEYLLKA
Sbjct: 350  TGDLTYYKKVMH-IRKLLQKMDRPNGLYPNYLNPRTGRWGQYHTSVGGLGDSFYEYLLKA 408

Query: 894  YLLFG--DEEYLYVFEEAYKAAMHYLHHDPWYIEVNMNSGATVW----------PLFNSL 1037
            +L+    D E   ++++A +A   +L        +  + G   +               L
Sbjct: 409  WLMSDKTDHEARKMYDDAIEAIEKHL--------IKKSRGGLTFIGEWKNGHLEKKMGHL 460

Query: 1038 QAFWPGLQVLAGD--------------VDPAIRTHAAFFSVWKKYGFTPEGFN----LAT 1163
              F  G+  L  D               + A   H ++     K G  PE F     +  
Sbjct: 461  ACFAGGMFALGADGSRADKAGHYLELGAEIARTCHESYDRTALKLG--PESFKFDGAVEA 518

Query: 1164 STVQNGQRSYPLRPELIESTYWLFKATRDFRYLDVGRDILASLQYAAKCPCGYCHISDV- 1340
              V+  ++ Y LRPE+IE+ ++L++ T D RY   G +   +++   +   G+  + DV 
Sbjct: 519  VAVRQAEKYYILRPEVIETYWYLWRFTHDPRYRQWGWEAALAIEKYCRVNGGFSGVKDVY 578

Query: 1341 -ETHKQDDHMESFFLAETVKYLWLLFDLAVGPDNIVENGPYKYIFSTEGHLLP 1496
              T   DD  +SFFLAET+KYL+LLF    G D +  +    ++F+TE H LP
Sbjct: 579  SSTPTHDDVQQSFFLAETLKYLYLLFS---GDDLLPLD---HWVFNTEAHPLP 625

>P33908:MA1A1_HUMAN Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA - Homo sapiens|
            (Human)
          Length = 653

 Score =  177 bits (449), Expect = 2e-43
 Identities = 147/470 (31%), Positives = 231/470 (49%), Gaps = 34/470 (7%)
 Frame = +3

Query: 201  RDEVKDMFYHAFDGYMQHAFPLDELRPLSCQGEDS--LGGY-ALTLIDSLDTLALLGDKE 371
            R ++K+M  HA++ Y  +A+ L+EL+P+S  G  S   G     T++D+LDTL ++  K 
Sbjct: 196  RAKIKEMMKHAWNNYKGYAWGLNELKPISKGGHSSSLFGNIKGATIVDALDTLFIMEMKH 255

Query: 372  RFAAGVEWVGKNVRFDINKTVSVFETNIRILGGLLSAHLIASDYATGMKIESYXXXXXXX 551
             F     WV +N+ F++N  +SVFE NIR +GGLLSA+     Y +G +I          
Sbjct: 256  EFEEAKSWVEENLDFNVNAEISVFEVNIRFVGGLLSAY-----YLSGEEI------FRKK 304

Query: 552  XXXXXXXXXPAFDTPTGIPFGSVNLLYGVDDD----ESKITSTAGGGTLTLEFGVLSRLT 719
                     PAF TP+GIP+  +N+  G+  +        +  A  GTL LEF  LS L+
Sbjct: 305  AVELGVKLLPAFHTPSGIPWALLNMKSGIGRNWPWASGGSSILAEFGTLHLEFMHLSHLS 364

Query: 720  NNTVFEQVTKNSVRGIWARRSK-LNLVGAHINVFTGEWTQKDAGIGTSIDSFYEYLLKAY 896
             N +F +   N +R +  +  K   L   ++N  +G+W Q    +G   DSFYEYLLKA+
Sbjct: 365  GNPIFAEKVMN-IRTVLNKLEKPQGLYPNYLNPSSGQWGQHHVSVGGLGDSFYEYLLKAW 423

Query: 897  LLFG--DEEYLYVFEEAYKAAMHYL--HHDPWYIEVNMNSGATVWPLFNSLQAFWPGLQV 1064
            L+    D E   ++ +A +A   +L          +    G  +      L  F  G+  
Sbjct: 424  LMSDKTDLEAKKMYFDAVQAIETHLIRKSSSGLTYIAEWKGGLLEHKMGHLTCFAGGMFA 483

Query: 1065 LAGDVDP--------------AIRTHAAFFSVWKKYGFTPEGFNL-----ATSTVQNGQR 1187
            L  D  P              A   H ++   + K G  PE F       A +T QN ++
Sbjct: 484  LGADAAPEGMAQHYLELGAEIARTCHESYNRTFMKLG--PEAFRFDGGVEAIATRQN-EK 540

Query: 1188 SYPLRPELIESTYWLFKATRDFRYLDVGRDILASLQYAAKCPCGYCHISDVET--HKQDD 1361
             Y LRPE++E+  ++++ T D +Y     + + +L+   +   GY  + DV       DD
Sbjct: 541  YYILRPEVMETYMYMWRLTHDPKYRKWAWEAVEALENHCRVNGGYSGLRDVYLLHESYDD 600

Query: 1362 HMESFFLAETVKYLWLLFDLAVGPDNIVENGPYK-YIFSTEGHLLPATPE 1508
              +SFFLAET+KYL+L+F      D+++   P + +IF++E HLLP  P+
Sbjct: 601  VQQSFFLAETLKYLYLIF----SDDDLL---PLEHWIFNSEAHLLPILPK 643

>P45700:MA1A1_MOUSE Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA - Mus musculus|
            (Mouse)
          Length = 655

 Score =  176 bits (445), Expect = 5e-43
 Identities = 150/471 (31%), Positives = 234/471 (49%), Gaps = 35/471 (7%)
 Frame = +3

Query: 201  RDEVKDMFYHAFDGYMQHAFPLDELRPLSCQGEDS--LGGY-ALTLIDSLDTLALLGDKE 371
            R ++K+M  HA++ Y ++A+ L+EL+P+S +G  S   G     T++D+LDTL ++G K 
Sbjct: 198  RAKIKEMMTHAWNNYKRYAWGLNELKPISKEGHSSSLFGNIKGATIVDALDTLFIMGMKT 257

Query: 372  RFAAGVEWVGKNVRFDINKTVSVFETNIRILGGLLSAHLIASDYATGMKIESYXXXXXXX 551
             F     W+ K + F++N  VSVFE NIR +GGLLSA+     Y +G +I          
Sbjct: 258  EFQEAKSWIKKYLDFNVNAEVSVFEVNIRFVGGLLSAY-----YLSGEEI------FRKK 306

Query: 552  XXXXXXXXXPAFDTPTGIPFGSVNLLYGVDDD----ESKITSTAGGGTLTLEFGVLSRLT 719
                     PAF TP+GIP+  +N+  G+  +        +  A  GTL LEF  LS L+
Sbjct: 307  AVELGVKLLPAFHTPSGIPWALLNMKSGIGRNWPWASGGSSILAEFGTLHLEFMHLSHLS 366

Query: 720  NNTVF-EQVTKNSVRGIWARRSK-LNLVGAHINVFTGEWTQKDAGIGTSIDSFYEYLLKA 893
             + VF E+V K  +R +  +  K   L   ++N  +G+W Q    +G   DSFYEYLLKA
Sbjct: 367  GDPVFAEKVMK--IRTVLNKLDKPEGLYPNYLNPSSGQWGQHHVSVGGLGDSFYEYLLKA 424

Query: 894  YLLFG--DEEYLYVFEEAYKAAMHYL--HHDPWYIEVNMNSGATVWPLFNSLQAFWPGLQ 1061
            +L+    D E   ++ +A +A   +L          +    G  +      L  F  G+ 
Sbjct: 425  WLMSDKTDLEAKKMYFDAVQAIETHLIRKSSGGLTYIAEWKGGLLEHKMGHLTCFAGGMF 484

Query: 1062 VLAGDVDPAIRT--------------HAAFFSVWKKYGFTPEGFNL-----ATSTVQNGQ 1184
             L  D  P  R               H ++   + K G  PE F       A +T QN +
Sbjct: 485  ALGADGAPEARAQHYLELGAEIARTCHESYNRTYVKLG--PEAFRFDGGVEAIATRQN-E 541

Query: 1185 RSYPLRPELIESTYWLFKATRDFRYLDVGRDILASLQYAAKCPCGYCHISDVETHKQ--D 1358
            + Y LRPE+IE+  ++++ T D +Y     + + +L+   +   GY  + DV   ++  D
Sbjct: 542  KYYILRPEVIETYMYMWRLTHDPKYRTWAWEAVEALESHCRVNGGYSGLRDVYIARESYD 601

Query: 1359 DHMESFFLAETVKYLWLLFDLAVGPDNIVENGPYK-YIFSTEGHLLPATPE 1508
            D  +SFFLAET+KYL+L+F      D+++   P + +IF+TE H  P   E
Sbjct: 602  DVQQSFFLAETLKYLYLIF----SDDDLL---PLEHWIFNTEAHPFPILRE 645

>Q9UKM7:MA1B1_HUMAN Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase|
            - Homo sapiens (Human)
          Length = 699

 Score =  175 bits (444), Expect = 7e-43
 Identities = 154/476 (32%), Positives = 232/476 (48%), Gaps = 36/476 (7%)
 Frame = +3

Query: 177  TPTEALRLRDEVKDMFYHAFDGYMQHAFPLDELRPLSCQGEDSLGGYALTLIDSLDTLAL 356
            TP      +  V D+F HA+ GY + A+  DEL+P+S    +  G   LTLID+LDT+ +
Sbjct: 242  TPVHLNYRQKGVIDVFLHAWKGYRKFAWGHDELKPVSRSFSEWFG-LGLTLIDALDTMWI 300

Query: 357  LGDKERFAAGVEWVGKNVRFDINKTVSVFETNIRILGGLLSAHLIASDYATGMKIESYXX 536
            LG ++ F    +WV K + F+ +  V++FE+ IRILGGLLSA+ ++ D     K E +  
Sbjct: 301  LGLRKEFEEARKWVSKKLHFEKDVDVNLFESTIRILGGLLSAYHLSGDSLFLRKAEDF-- 358

Query: 537  XXXXXXXXXXXXXXPAFDTPTGIPFGSVNLLYGV--------DDDESKITSTAGGGTLTL 692
                          PAF TP+ IP+  VN+  GV        D   +++TS      + L
Sbjct: 359  ---------GNRLMPAFRTPSKIPYSDVNIGTGVAHPPRWTSDSTVAEVTS------IQL 403

Query: 693  EFGVLSRLTNNTVFEQVTKNSVRGIWARRSKLN-LVGAHINVFTGEWTQKDA-GIGTSID 866
            EF  LSRLT +  F++  +   + I     K + LV   IN  +G +T      +G   D
Sbjct: 404  EFRELSRLTGDKKFQEAVEKVTQHIHGLSGKKDGLVPMFINTHSGLFTHLGVFTLGARAD 463

Query: 867  SFYEYLLKAYLLFGDEE--YLYVFEEAYKAAMHYL--HHDPWYIE-VNMNSGATVWPLFN 1031
            S+YEYLLK ++  G +E   L  + EA +    +L  H +P  +  V   +        +
Sbjct: 464  SYYEYLLKQWIQGGKQETQLLEDYVEAIEGVRTHLLRHSEPSKLTFVGELAHGRFSAKMD 523

Query: 1032 SLQAFWPGLQVL-------AGDVDPAIRTHAAFFSVWKKY--GFTPE--GFNLATS---- 1166
             L  F PG   L       A  ++ A       + + ++   G +PE   FNL       
Sbjct: 524  HLVCFLPGTLALGVYHGLPASHMELAQELMETCYQMNRQMETGLSPEIVHFNLYPQPGRR 583

Query: 1167 --TVQNGQRSYPLRPELIESTYWLFKATRDFRYLDVGRDILASLQYAAKCPC-GYCHISD 1337
               V+   R   LRPE +ES ++L++ T D +Y D G +IL S     + P  GY  I++
Sbjct: 584  DVEVKPADRHNLLRPETVESLFYLYRVTGDRKYQDWGWEILQSFSRFTRVPSGGYSSINN 643

Query: 1338 VETHKQD---DHMESFFLAETVKYLWLLFDLAVGPDNIVENGPYKYIFSTEGHLLP 1496
            V+  ++    D MESFFL ET+KYL+LLF       N++      Y+F+TE H LP
Sbjct: 644  VQDPQKPEPRDKMESFFLGETLKYLFLLFS---DDPNLLSLD--AYVFNTEAHPLP 694

>P53624:MA121_DROME Mannosyl-oligosaccharide alpha-1,2-mannosidase isoform 1 - Drosophila|
            melanogaster (Fruit fly)
          Length = 667

 Score =  175 bits (443), Expect = 9e-43
 Identities = 150/478 (31%), Positives = 225/478 (47%), Gaps = 46/478 (9%)
 Frame = +3

Query: 201  RDEVKDMFYHAFDGYMQHAFPLDELRPLSCQGEDS--LGGYAL--TLIDSLDTLALLGDK 368
            R +VK+M  HA+  Y  +A+  +ELRPLS +   +   G Y L  T++D LDTL ++G +
Sbjct: 201  RQKVKEMMEHAWHNYKLYAWGKNELRPLSQRPHSASIFGSYDLGATIVDGLDTLYIMGLE 260

Query: 369  ERFAAGVEWVGKNVRFD-INKTVSVFETNIRILGGLLSAHLIASDYATGMKIESYXXXXX 545
            + +  G +W+ +    D I+  +SVFETNIR +GG+L+ +    D     K +       
Sbjct: 261  KEYREGRDWIERKFSLDNISAELSVFETNIRFVGGMLTLYAFTGDPLYKEKAQHVADKLL 320

Query: 546  XXXXXXXXXXXPAFDTPTGIPFGSVNLLYGVDDDESKITSTAGGG--------TLTLEFG 701
                       PAF TPTGIP+  VN   GV    +K    A GG        TL LEF 
Sbjct: 321  -----------PAFQTPTGIPYALVNTKTGV----AKNYGWASGGSSILSEFGTLHLEFA 365

Query: 702  VLSRLTNNTVFEQVTKNSVRGIWARRSKLNLVGAHINVFTGEWTQKDAGIGTSIDSFYEY 881
             LS +T N ++ +  +   + +        L    +N  TG+W Q    +G   DS+YEY
Sbjct: 366  YLSDITGNPLYRERVQTIRQVLKEIEKPKGLYPNFLNPKTGKWGQLHMSLGALGDSYYEY 425

Query: 882  LLKAYLLFG--DEEYLYVFEEAYKAAMHYLHHDPWYIEVNMNSGATVW----------PL 1025
            LLKA+L  G  DEE   +F+EA  A +  +        V  + G   +            
Sbjct: 426  LLKAWLQSGQTDEEAREMFDEAMLAILDKM--------VRTSPGGLTYVSDLKFDRLEHK 477

Query: 1026 FNSLQAFWPGLQVLAG------------DVDPAIRT--HAAFFSVWKKYGFTPEGFNLAT 1163
             + L  F  GL  L              +V   I    H ++     + G  PE F  + 
Sbjct: 478  MDHLACFSGGLFALGAATRQNDYTDKYMEVGKGITNTCHESYIRAPTQLG--PEAFRFSE 535

Query: 1164 STVQNGQRS----YPLRPELIESTYWLFKATRDFRYLDVGRDILASLQYAAKCPCGYCHI 1331
            +      RS    Y LRPE  ES + L++ T D +Y D G + + +L+   +   GYC +
Sbjct: 536  AVEARALRSQEKYYILRPETFESYFVLWRLTHDQKYRDWGWEAVLALEKHCRTAHGYCGL 595

Query: 1332 SDV--ETHKQDDHMESFFLAETVKYLWLLF-DLAVGPDNIVENGPYKYIFSTEGHLLP 1496
             +V  +  ++DD  +SFFLAET+KYL+LLF D +V P +       +++F+TE H LP
Sbjct: 596  RNVYQQEPQKDDVQQSFFLAETLKYLYLLFSDDSVLPLD-------EWVFNTEAHPLP 646

>P53625:MA122_DROME Mannosyl-oligosaccharide alpha-1,2-mannosidase isoform 2 - Drosophila|
            melanogaster (Fruit fly)
          Length = 643

 Score =  172 bits (435), Expect = 7e-42
 Identities = 149/478 (31%), Positives = 224/478 (46%), Gaps = 46/478 (9%)
 Frame = +3

Query: 201  RDEVKDMFYHAFDGYMQHAFPLDELRPLSCQGEDS--LGGYAL--TLIDSLDTLALLGDK 368
            R++V  M  HA+  Y  +A+  +ELRPLS +   +   G Y L  T++D LDTL ++G +
Sbjct: 177  RNQVVKMMEHAWHNYKLYAWGKNELRPLSQRPHSASIFGSYDLGATIVDGLDTLYIMGLE 236

Query: 369  ERFAAGVEWVGKNVRFD-INKTVSVFETNIRILGGLLSAHLIASDYATGMKIESYXXXXX 545
            + +  G +W+ +    D I+  +SVFETNIR +GG+L+ +    D     K +       
Sbjct: 237  KEYREGRDWIERKFSLDNISAELSVFETNIRFVGGMLTLYAFTGDPLYKEKAQHVADKLL 296

Query: 546  XXXXXXXXXXXPAFDTPTGIPFGSVNLLYGVDDDESKITSTAGGG--------TLTLEFG 701
                       PAF TPTGIP+  VN   GV    +K    A GG        TL LEF 
Sbjct: 297  -----------PAFQTPTGIPYALVNTKTGV----AKNYGWASGGSSILSEFGTLHLEFA 341

Query: 702  VLSRLTNNTVFEQVTKNSVRGIWARRSKLNLVGAHINVFTGEWTQKDAGIGTSIDSFYEY 881
             LS +T N ++ +  +   + +        L    +N  TG+W Q    +G   DS+YEY
Sbjct: 342  YLSDITGNPLYRERVQTIRQVLKEIEKPKGLYPNFLNPKTGKWGQLHMSLGALGDSYYEY 401

Query: 882  LLKAYLLFG--DEEYLYVFEEAYKAAMHYLHHDPWYIEVNMNSGATVW----------PL 1025
            LLKA+L  G  DEE   +F+EA  A +  +        V  + G   +            
Sbjct: 402  LLKAWLQSGQTDEEAREMFDEAMLAILDKM--------VRTSPGGLTYVSDLKFDRLEHK 453

Query: 1026 FNSLQAFWPGLQVLAG------------DVDPAIRT--HAAFFSVWKKYGFTPEGFNLAT 1163
             + L  F  GL  L              +V   I    H ++     + G  PE F  + 
Sbjct: 454  MDHLACFSGGLFALGAATRQNDYTDKYMEVGKGITNTCHESYIRAPTQLG--PEAFRFSE 511

Query: 1164 STVQNGQRS----YPLRPELIESTYWLFKATRDFRYLDVGRDILASLQYAAKCPCGYCHI 1331
            +      RS    Y LRPE  ES + L++ T D +Y D G + + +L+   +   GYC +
Sbjct: 512  AVEARALRSQEKYYILRPETFESYFVLWRLTHDQKYRDWGWEAVLALEKHCRTAHGYCGL 571

Query: 1332 SDV--ETHKQDDHMESFFLAETVKYLWLLF-DLAVGPDNIVENGPYKYIFSTEGHLLP 1496
             +V  +  ++DD  +SFFLAET+KYL+LLF D +V P +       +++F+TE H LP
Sbjct: 572  RNVYQQEPQKDDVQQSFFLAETLKYLYLLFSDDSVLPLD-------EWVFNTEAHPLP 622

>Q9NR34:MA1C1_HUMAN Mannosyl-oligosaccharide 1,2-alpha-mannosidase IC - Homo sapiens|
            (Human)
          Length = 630

 Score =  169 bits (427), Expect = 6e-41
 Identities = 145/467 (31%), Positives = 222/467 (47%), Gaps = 35/467 (7%)
 Frame = +3

Query: 201  RDEVKDMFYHAFDGYMQHAFPLDELRPLSCQGEDS--LGGYA-LTLIDSLDTLALLGDKE 371
            R+++K+M   A+  Y ++A   +ELRPL+  G +    GG +  T+IDSLDTL L+  KE
Sbjct: 175  REKIKEMMQFAWQSYKRYAMGKNELRPLTKDGYEGNMFGGLSGATVIDSLDTLYLMELKE 234

Query: 372  RFAAGVEWVGKNVRFDINKTVSVFETNIRILGGLLSAHLIASDYATGMKIESYXXXXXXX 551
             F     WVG++   +++   S+FE NIR +GGLLSA      Y TG ++          
Sbjct: 235  EFQEAKAWVGESFHLNVSGEASLFEVNIRYIGGLLSAF-----YLTGEEV------FRIK 283

Query: 552  XXXXXXXXXPAFDTPTGIPFGSVNLLYGVDDDESKITST--AGGGTLTLEFGVLSRLTNN 725
                     PAF+TPTGIP G V+   G     +  +S+  A  G+L LEF  L+ L+ N
Sbjct: 284  AIRLGEKLLPAFNTPTGIPKGVVSFKSGNWGWATAGSSSILAEFGSLHLEFLHLTELSGN 343

Query: 726  TVFEQVTKNSVRGIWARRSKLNLVGAHINVFTGEWTQKDAGIGTSIDSFYEYLLKAYLLF 905
             VF +  +N  + +        L    ++  +G W Q    +G   DSFYEYL+K++L+ 
Sbjct: 344  QVFAEKVRNIRKVLRKIEKPFGLYPNFLSPVSGNWVQHHVSVGGLGDSFYEYLIKSWLMS 403

Query: 906  G--DEEYLYVFEEAYKAAMHYLHHDPWYIEVNMNSGATVW----------PLFNSLQAFW 1049
            G  D E   ++ EA +A   YL        +N++ G   +               L  F 
Sbjct: 404  GKTDMEAKNMYYEALEAIETYL--------LNVSPGGLTYIAEWRGGILDHKMGHLACFS 455

Query: 1050 PGLQVL-AGDVDPAIRT-------------HAAFFSVWKKYGFTPEGFNLATSTV--QNG 1181
             G+  L A D     R              H ++     K G     FN     V  Q  
Sbjct: 456  GGMIALGAEDAKEEKRAHYRELAAQITKTCHESYARSDTKLGPEAFWFNSGREAVATQLS 515

Query: 1182 QRSYPLRPELIESTYWLFKATRDFRYLDVGRDILASLQYAAKCPCGYCHISDV--ETHKQ 1355
            +  Y LRPE++ES  +L++ T +  Y + G +++ +L+   +   G+  I DV   T   
Sbjct: 516  ESYYILRPEVVESYMYLWRQTHNPIYREWGWEVVLALEKYCRTEAGFSGIQDVYSSTPNH 575

Query: 1356 DDHMESFFLAETVKYLWLLFDLAVGPDNIVENGPYKYIFSTEGHLLP 1496
            D+  +SFFLAET+KYL+LLF      D+++      ++F+TE H LP
Sbjct: 576  DNKQQSFFLAETLKYLYLLF----SEDDLL--SLEDWVFNTEAHPLP 616

>O02773:MA1A1_PIG Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA - Sus scrofa (Pig)|
          Length = 659

 Score =  168 bits (426), Expect = 8e-41
 Identities = 146/471 (30%), Positives = 226/471 (47%), Gaps = 39/471 (8%)
 Frame = +3

Query: 201  RDEVKDMFYHAFDGYMQHAFPLDELRPLSCQGEDS--LGGY-ALTLIDSLDTLALLGDKE 371
            R ++K+M  HA++ Y  +A+  +EL+P+S  G  S   G     T++D+LDTL ++  K 
Sbjct: 202  RAKIKEMMKHAWNNYKLYAWGKNELKPVSKGGHSSSLFGNIKGATIVDALDTLFIMKMKN 261

Query: 372  RFAAGVEWVGKNVRFDINKTVSVFETNIRILGGLLSAHLIASDYATGMKIESYXXXXXXX 551
             F     WV +++ F++N  VSVFE NIR +GGL+SA+     Y +G +I          
Sbjct: 262  EFEEAKAWVEEHLNFNVNAEVSVFEVNIRFIGGLISAY-----YLSGEEI------FRKK 310

Query: 552  XXXXXXXXXPAFDTPTGIPFGSVNLLYGVDDD----ESKITSTAGGGTLTLEFGVLSRLT 719
                     PAF TP+GIP+  +N+  G+  +        +  A  GTL LEF  LS L+
Sbjct: 311  AVELGVKLLPAFYTPSGIPWALLNIKSGIGRNWPWASGGSSILAEFGTLHLEFIHLSYLS 370

Query: 720  NNTVFEQVTKNSVRGIWARRSKLNLVGAHINVFTGEWTQKDAGIGTSIDSFYEYLLKAYL 899
             N  F +   N  + +        L   ++N  +G+W Q    +G   DSFYEYLLKA+L
Sbjct: 371  GNPFFAEKVMNIRKVLNNLEKPQGLYPNYLNPNSGQWGQYHVSVGGLGDSFYEYLLKAWL 430

Query: 900  LFG--DEEYLYVFEEAYKAAMHYLHHDPWYIEVNMN--------SGATVWPLFNSLQAFW 1049
            +    D E   ++ +A KA   +L      I  + N         G  +      L  F 
Sbjct: 431  MSDKTDLEAKKMYFDAIKAIETHL------IRKSRNGLTYIAEWKGGLLEHKMGHLTCFA 484

Query: 1050 PGLQVLAGDVDP--------------AIRTHAAFFSVWKKYGFTPEGFNL-----ATSTV 1172
             G+  L  D  P              A   H ++   + K G  PE F       A +T 
Sbjct: 485  GGMFALGADDAPDGLTQHYLQLGAEIARTCHESYSRTFVKLG--PEAFRFDGGVEAIATR 542

Query: 1173 QNGQRSYPLRPELIESTYWLFKATRDFRYLDVGRDILASLQYAAKCPCGYCHISDVETHK 1352
            QN ++ Y LRPE++E+  ++++ T D +Y     + + +L+   +   GY  + DV    
Sbjct: 543  QN-EKYYILRPEVVETYLYMWRLTHDPKYRKWAWEAVEALEKHCRVNGGYSGLRDVYVSA 601

Query: 1353 Q--DDHMESFFLAETVKYLWLLFDLAVGPDNIVENGPYK-YIFSTEGHLLP 1496
            Q  DD  +SFFLAET+KYL+L+F      D+++   P + +IF+TE H LP
Sbjct: 602  QTYDDVQQSFFLAETLKYLYLIF----SDDDLL---PLEHWIFNTEAHPLP 645

>Q18788:MAN12_CAEEL Mannosyl-oligosaccharide 1,2-alpha-mannosidase C52E4.5 -|
            Caenorhabditis elegans
          Length = 590

 Score =  147 bits (370), Expect = 3e-34
 Identities = 136/475 (28%), Positives = 228/475 (48%), Gaps = 43/475 (9%)
 Frame = +3

Query: 201  RDEVKDMFYHAFDGYMQHAFPLDELRPLSCQ--GEDSLGGYAL--TLIDSLDTLALLGDK 368
            R +VK+M  HA++GY  +++  +ELRP+S +   ++  GG  +  T++D+ DTL ++  K
Sbjct: 140  RQKVKEMMIHAWEGYKNYSWGANELRPMSKKPNSQNIFGGSQMPATIVDAADTLFIMDLK 199

Query: 369  ERFAAGVEWVGKNVRF-DINKTVSVFETNIRILGGLLSAHLIASDYATGMKIESYXXXXX 545
            +++    +++  N        T+SVFET IR LGGLLS + +  +      IE       
Sbjct: 200  DKYKEARDYIENNFSMAKSTSTLSVFETTIRFLGGLLSLYALTQE---SFYIEK------ 250

Query: 546  XXXXXXXXXXXPAFDTPTGIPFGSVNLL------YGVDDDESKITSTAGGGTLTLEFGVL 707
                       PAF+TP+GIP  ++++       YG  +    I S  G  +L LEF  L
Sbjct: 251  --AREVGEALLPAFNTPSGIPKSNLDVASKHASNYGWANGGQSILSEIG--SLHLEFLYL 306

Query: 708  SRLTNNTVFEQVTKNSVRGIWARRSKLN-LVGAHINVFTGEWTQKDAGIGTSIDSFYEYL 884
            SR++N  +FE+  K  VR    +  K N L   +IN  TG++T     +G   DSFYEYL
Sbjct: 307  SRISNAPIFEKKVKK-VRDALEKAEKPNGLYSNYINPDTGKFTGSHMSLGALGDSFYEYL 365

Query: 885  LKAYLL--FGDEEYLYVFEEAYKAAMHYLHHDPWYIEVNMNSGATVWPLFNSLQA----- 1043
            +K+Y+   + D +   ++ +   A   ++      I+V+  S  T     N+ QA     
Sbjct: 366  IKSYVQSNYTDTQAKNMYWDVSDAIQKHM------IKVSKQSNLTYTVELNNGQAQHKMG 419

Query: 1044 ----FWPG---LQVLAGDVDP------------AIRTHAAFFSVWKKYGFTPEGF---NL 1157
                F PG   LQ +  D +             A   H ++       G  PE F     
Sbjct: 420  HLACFVPGMFALQAINEDTEEEKLRIMTLAEELAKTCHESYIRSETHIG--PEMFYFNER 477

Query: 1158 ATSTVQNGQRSYPLRPELIESTYWLFKATRDFRYLDVGRDILASLQYAAKCPCGYCHISD 1337
              +T ++ +  Y  RPE+IE  ++L++ T    Y D   D + +++   +   G+  + +
Sbjct: 478  DEATSKHSENGYIQRPEVIEGWFYLWRLTGKTMYRDWVWDAVQAIEKYCRVDSGFTGLQN 537

Query: 1338 VETHK--QDDHMESFFLAETVKYLWLLFDLAVGPDNIVENGPYKYIFSTEGHLLP 1496
            V   K  ++D M+SFFLAE +KY +L F      ++++     K++F+TE H +P
Sbjct: 538  VYNPKAGREDVMQSFFLAEFLKYAYLTF----ADESLISLD--KWVFNTEAHPVP 586

>Q8J0Q0:MNS1_CANAL Mannosyl-oligosaccharide 1,2-alpha-mannosidase - Candida albicans|
            (Yeast)
          Length = 565

 Score =  142 bits (357), Expect = 8e-33
 Identities = 129/489 (26%), Positives = 230/489 (47%), Gaps = 55/489 (11%)
 Frame = +3

Query: 195  RLRDEVKDMFYHAFDGYMQHAFPLDELRPLSCQGEDSLGGYAL--TLIDSLDTLALLGDK 368
            R + EV+     ++  Y ++ +  D   P+  +GE+ +G   L   ++DSLDTL ++   
Sbjct: 37   RAQSEVRQAILDSWHTYEKYGWGYDVYHPIKQEGEN-MGPKPLGWMIVDSLDTLMIMDCP 95

Query: 369  ERFAAGVEWVGKNVRFDINKTVSVFETNIRILGGLLSAHLIASDYATGMKIESYXXXXXX 548
            E  +   +W+  ++ +  +  V+ FET IR+LGGLLSA+  ++D     K          
Sbjct: 96   EEVSRARDWIKNDLDYTFDYNVNTFETTIRMLGGLLSAYHFSNDDVYLDKAVQLANALHG 155

Query: 549  XXXXXXXXXXPAFDTPTGIPFGSVNLLYGV---DDDESKITSTAGGGTLTLEFGVLSRLT 719
                       A+D+P+GIP+ SVNL  G    +  ++  +STA   T+ LE   LS+LT
Sbjct: 156  -----------AYDSPSGIPYSSVNLKSGKGIKNHVDNGASSTAEAATVQLEMKYLSKLT 204

Query: 720  NNTVFEQVTKNSVRGIWARRSKLNLVGAHINVFTGEWTQKDAGIGTSIDSFYEYLLKAYL 899
               ++  + +  ++ + + + +  LV  ++N  TG++      +G+  DS+YEYLLK YL
Sbjct: 205  GEILWWNLAEKVMQVLESNKPQDGLVPIYVNPDTGKYQGHLIRLGSRGDSYYEYLLKQYL 264

Query: 900  LFGDEEYLY--VFEEAYKAAMHYLHHDPW-----YI-EVNMNSGATVWPLFNSLQAFWPG 1055
                +E +Y  ++ E+ +    +L  D +     +I E++   G  +    + L  F+ G
Sbjct: 265  QTNKQELVYWDMYRESVEGVKKHLVSDSYPSGLTFIGELDNGIGGKLSTKMDHLVCFYGG 324

Query: 1056 LQVLAGDVDPAIRTHAAF------------------FSVWKKY------GFTPE--GFNL 1157
            L  L       +    +                   ++ +K Y      G +PE   FN 
Sbjct: 325  LLALGATGGLTLNEAQSLKSWNEEREADFKLGEELTYTCYKMYHDVSPTGLSPEIVVFNE 384

Query: 1158 ATS-----TVQNGQRSYPLRPELIESTYWLFKATRDFRYLDVGRDILAS-LQYA----AK 1307
             TS      ++   R    RPE +ES ++L++ T D +Y ++G +I  + ++Y     ++
Sbjct: 385  DTSKSKDFIIKPLDRHNLQRPETVESLFYLYRLTGDVKYREMGYEIFQNFIKYTKVVNSE 444

Query: 1308 CPCGYCHISDVETH------KQDDHMESFFLAETVKYLWLLFDLAVGPDNIVENGPYKYI 1469
                +  +SDV +       K  D+ ESF+ AET+KYL+LLF      D+  +     Y+
Sbjct: 445  GEVSFSSLSDVTSFDSNGLPKFKDNTESFWWAETLKYLYLLF------DDTNKIPLTDYV 498

Query: 1470 FSTEGHLLP 1496
            F+TE H  P
Sbjct: 499  FNTEAHPFP 507

>P32906:MNS1_YEAST Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase|
            - Saccharomyces cerevisiae (Baker's yeast)
          Length = 549

 Score =  133 bits (335), Expect = 3e-30
 Identities = 139/512 (27%), Positives = 213/512 (41%), Gaps = 75/512 (14%)
 Frame = +3

Query: 198  LRDEVKDMFYHAFDGYMQHAFPLDELRPLSCQGEDSLGG---YALTLIDSLDTLALLGD- 365
            +RD ++ MF  ++  Y +H +  D   P+     +   G       ++DS+DTL L+ + 
Sbjct: 38   MRDRIESMFLESWRDYSKHGWGYDVYGPIEHTSHNMPRGNQPLGWIIVDSVDTLMLMYNS 97

Query: 366  ----KERFAAGVE----WVGKNVRFDINKTVSVFETNIRILGGLLSAHLIASDYATGMKI 521
                K  F A ++    W+   + FDI+  V+VFET IR+LGGLLSA+ ++     G K 
Sbjct: 98   STLYKSEFEAEIQRSEHWINDVLDFDIDAEVNVFETTIRMLGGLLSAYHLSDVLEVGNK- 156

Query: 522  ESYXXXXXXXXXXXXXXXXPAFDTPTGIPFGSVNLLYG---VDDDESKITSTAGGGTLTL 692
                                   T TGIP+ S+NL  G    +  +   +STA   TL +
Sbjct: 157  ---TVYLNKAIDLGDRLALAFLSTQTGIPYSSINLHSGQAVKNHADGGASSTAEFTTLQM 213

Query: 693  EFGVLSRLTNNTVFEQVTKNSVRGIWARRSKLNLVGAHINVF----TGEWTQKDAGIGTS 860
            EF  L+ LT N  + ++ +     ++     LN     + ++    TG++       G+ 
Sbjct: 214  EFKYLAYLTGNRTYWELVERVYEPLYKNNDLLNTYDGLVPIYTFPDTGKFGASTIRFGSR 273

Query: 861  IDSFYEYLLKAYLLFGDEEYLYVFEEAYKAAMHYL-----HHDPWYI-EVNMNSGATVWP 1022
             DSFYEYLLK YLL  +  Y  ++ ++ +    +L         WYI E        + P
Sbjct: 274  GDSFYEYLLKQYLLTHETLYYDLYRKSMEGMKKHLLAQSKPSSLWYIGEREQGLHGQLSP 333

Query: 1023 LFNSLQAFWPGLQVLAGDVDPAIRTHAA----FFSV-------W---------------- 1121
              + L  F  GL  LA      +  H A    FFS+       W                
Sbjct: 334  KMDHLVCFMGGL--LASGSTEGLSIHEARRRPFFSLSLERKSDWDLAKGITDTCYQMYKQ 391

Query: 1122 KKYGFTPE--GFNLATSTVQNGQRS-------YPL------RPELIESTYWLFKATRDFR 1256
               G  PE   FN          RS        PL      RPE +ES  +++  + D +
Sbjct: 392  SSSGLAPEIVVFNDGNIKQDGWWRSSVGDFFVKPLDRHNLQRPETVESIMFMYHLSHDHK 451

Query: 1257 YLDVGRDILASLQYAAKCPCG------YCHISDVET--HKQDDHMESFFLAETVKYLWLL 1412
            Y + G +I  S        C       +  +SD  T   K+ ++MESF+LAET+KYL++L
Sbjct: 452  YREWGAEIATSFFENTCVDCNDPKLRRFTSLSDCITLPTKKSNNMESFWLAETLKYLYIL 511

Query: 1413 FDLAVGPDNIVENGPYKYIFSTEGHLLPATPE 1508
            F        + E    K +F+TE H  P   E
Sbjct: 512  F--------LDEFDLTKVVFNTEAHPFPVLDE 535

>P31723:MAN12_PENCI Mannosyl-oligosaccharide alpha-1,2-mannosidase precursor -|
            Penicillium citrinum
          Length = 511

 Score =  132 bits (331), Expect = 8e-30
 Identities = 121/467 (25%), Positives = 199/467 (42%), Gaps = 39/467 (8%)
 Frame = +3

Query: 204  DEVKDMFYHAFDGYMQHAFPLDELRPLSCQGEDSLGGYALTLIDSLDTLALLGDKERFAA 383
            D VK+ F HA++GYM++AFP DEL P+S    DS  G+  + +D+L T  ++G  +   A
Sbjct: 42   DAVKEAFQHAWNGYMKYAFPHDELTPVSNGHADSRNGWGASAVDALSTAVIMGKADVVNA 101

Query: 384  GVEWVGKNVRFDINKTVSVFETNIRILGGLLSAH-LIASDYATGMKIESYXXXXXXXXXX 560
             +E V        + TVS+FET IR L G+LS + L+       +  +            
Sbjct: 102  ILEHVADIDFSKTSDTVSLFETTIRYLAGMLSGYDLLQGPAKNLVDNQDLIDGLLDQSRN 161

Query: 561  XXXXXXPAFDTPTGIPFGSVNLLYGVDDDESKITSTAGGGTLTLEFGVLSRLTNNTVFEQ 740
                   AFDTP+G+P+ ++N+     +D +     A  GTL LE+  LS LT +  + +
Sbjct: 162  LADVLKFAFDTPSGVPYNNINIT-SHGNDGATTNGLAVTGTLVLEWTRLSDLTGDEEYAK 220

Query: 741  VTKNSVRGIWARRSKLN-----LVGAHINVFTGEWTQKDAGIGTSIDSFYEYLLKAYLL- 902
            +++ +   +   +   +     LVG+ IN+  G++           DSFYEYL+K Y+  
Sbjct: 221  LSQKAESYLLKPQPSSSEPFPGLVGSSININDGQFADSRVSWNGGDDSFYEYLIKMYVYD 280

Query: 903  -----FGDEEYLYVFEEAYKAAMHYLHHDPWYIEVNMNSGATVWPLFNSLQAFWPGLQVL 1067
                    + ++   E   K    +    P    ++  S          L  F  G  +L
Sbjct: 281  PKRFETYKDRWVLAAESTIKHLKSHPKSRPDLTFLSSYSNRNYDLSSQHLTCFDGGSFLL 340

Query: 1068 AGDV-----------DPAIRTHAAFFSVWKKYGFTPEGFNLATSTVQNGQR--------- 1187
             G V           +      A + S   K G  P+ +      V + Q+         
Sbjct: 341  GGTVLDRQDFIDFGLELVDGCEATYNSTLTKIG--PDSWGWDPKKVPSDQKEFYEKAGFY 398

Query: 1188 ----SYPLRPELIESTYWLFKATRDFRYLDVGRDILASLQYAAKCPCGYCHISDVET--- 1346
                SY LRPE+IES Y+  + T    Y D   +   ++    +   G+  +SDV     
Sbjct: 399  ISSGSYVLRPEVIESFYYAHRVTGKEIYRDWVWNAFVAINSTCRTDSGFAAVSDVNKANG 458

Query: 1347 HKQDDHMESFFLAETVKYLWLLFDLAVGPDNIVENGPYKYIFSTEGH 1487
              + D+ ESF  AE +KY +L          + + G   ++++TE H
Sbjct: 459  GSKYDNQESFLFAEVMKYSYLAHS-EDAAWQVQKGGKNTFVYNTEAH 504

>Q9P7C3:YKU1_SCHPO Putative mannosyl-oligosaccharide 1,2-alpha-mannosidase -|
            Schizosaccharomyces pombe (Fission yeast)
          Length = 521

 Score =  125 bits (313), Expect = 1e-27
 Identities = 133/481 (27%), Positives = 205/481 (42%), Gaps = 52/481 (10%)
 Frame = +3

Query: 210  VKDMFYHAFDGYMQHAFPLDELRPLSCQGEDSLG-GYALTLIDSLDTLALLGDKERFAAG 386
            +K  F  ++  Y  + +  DE  P+  +G + L  G    +IDSLDT+ ++G  E+    
Sbjct: 50   IKKTFIESWTDYETYGWGKDEYYPIIKRGRNYLRKGMGWMIIDSLDTMMIMGLDEQVLRA 109

Query: 387  VEWVGKNVRFDIN-KTVSVFETNIRILGGLLSAHLIASDYATGMKIESYXXXXXXXXXXX 563
             EWV  ++ ++ + + VSVFET IRILGGLLS++ ++ D                     
Sbjct: 110  REWVNNSLTWNQDDEEVSVFETTIRILGGLLSSYHLSQD-----------KLYLDRAVDL 158

Query: 564  XXXXXPAFDTPTGIPFGSVNLLYGVDDDESK----ITSTAGGGTLTLEFGVLSRLTNNTV 731
                  A++T TG+P  +VNL  G      +      STA  GT+ +E   LS LT +  
Sbjct: 159  ADRLLAAYNTSTGLPRSNVNL--GTRKSRKRTREYFVSTAESGTVQMELRYLSYLTGDPK 216

Query: 732  FEQVTKNSVRGIW--ARRSKLNLVGAHINVFTGEWTQKDAGIGTSIDSFYEYLLK--AYL 899
            +      ++  +   A  S   LV   +N+ TG +  ++  +G+  DS+YEYLLK    L
Sbjct: 217  YWITADKTMEVLLGDATWSHTGLVPITVNLITGAYVGRNIRLGSHGDSYYEYLLKQDLQL 276

Query: 900  LFGDEEYLYVFEEAYKAAMHYL------HHDPWYIEVNMNSGATVWPLFNSLQAFWPGLQ 1061
                  Y   F+ +    + YL      +H  +  E+         P  + L  F PG  
Sbjct: 277  FSSGTVYRKAFDLSVDGIIEYLLNYTTPNHFAYIAELPGGLEHAQLPKMDHLVCFLPGTL 336

Query: 1062 VLA---GDVDPAIRT---------------HAAFFSVWKKYGFTPEGFNLATSTV----- 1172
            +     G    A RT                    + ++ Y  T  G  LA   V     
Sbjct: 337  MWGATNGTSLEAARTSKNWGTRQERDVKLAQELMRTCYEMYNMTATG--LAPEIVFFDVD 394

Query: 1173 QNGQRSYP--------LRPELIESTYWLFKATRDFRYLDVGRDILASLQYAAKCP--CGY 1322
            Q     Y         +RPE +ES + L++ TRD  Y + G +I  S    ++ P    +
Sbjct: 395  QTKNEIYSKRRDQHNLMRPETVESLFILYRITRDEIYREWGWNIFVSFLRYSRLPGRDAF 454

Query: 1323 CHISDVETHK---QDDHMESFFLAETVKYLWLLFDLAVGPDNIVENGPYKYIFSTEGHLL 1493
              +  VE+ K   Q D  ESF+ AET+KYL+LLF+     D+        Y F+TE H  
Sbjct: 455  TCLDSVESKKVKDQRDKTESFWFAETLKYLYLLFE-----DDFSILPLTNYTFNTEAHPF 509

Query: 1494 P 1496
            P
Sbjct: 510  P 510

>Q8K4Z5:SF3A1_MOUSE Splicing factor 3 subunit 1 - Mus musculus (Mouse)|
          Length = 791

 Score = 34.7 bits (78), Expect = 1.8
 Identities = 27/85 (31%), Positives = 37/85 (43%)
 Frame = +3

Query: 1872 PPDEPLETGSRTQYLENIVVTGDSEPVEVSGSSQGNTENLAEDTTLGISEQIEVTAAEEV 2051
            PP  P E G+R    E     G+SE VE+   S    +  AE+T   + +  +V   +E 
Sbjct: 297  PPTTPEELGARILIQERYEKFGESEEVEMEVESDEEDQEKAEETPSQLDQDTQVQDMDE- 355

Query: 2052 GSQDIHIEDGTS*PME*APIFPPNL 2126
            GS D   E+G   P       PP L
Sbjct: 356  GSDD--EEEGQKVPPPPETPMPPPL 378

>Q8YRV2:CRCB_ANASP Protein crcB homolog - Anabaena sp. (strain PCC 7120)|
          Length = 157

 Score = 33.9 bits (76), Expect = 3.1
 Identities = 15/35 (42%), Positives = 19/35 (54%)
 Frame = +3

Query: 306 LGGYALTLIDSLDTLALLGDKERFAAGVEWVGKNV 410
           LG Y      +LDT  LLGD+   AAG  W G ++
Sbjct: 106 LGAYTTFSTYALDTFTLLGDRNLLAAGFYWAGSSI 140

>Q12205:YL057_YEAST Uncharacterized glycosyl hydrolase YLR057W - Saccharomyces|
           cerevisiae (Baker's yeast)
          Length = 849

 Score = 33.5 bits (75), Expect = 4.1
 Identities = 43/155 (27%), Positives = 63/155 (40%), Gaps = 10/155 (6%)
 Frame = +3

Query: 315 YALTLIDSLDTLALLGDKERFAAGVEWVGKNVRFDIN------KTVSVFETNIRILGGLL 476
           + + LIDSLDTL L G+ + F   V  +     FD        + + + +   R+L GLL
Sbjct: 193 WPIDLIDSLDTLYLCGETKLFQDSVNIIED---FDFRVPPLAMEVIDIPDITTRVLEGLL 249

Query: 477 SAHLIASDYATGMKIESYXXXXXXXXXXXXXXXXPAFDTPTGIPFGSVNLLYGVDDDESK 656
           SA+ ++ D     K +                   +FDTP  IP   +   +  D     
Sbjct: 250 SAYELSMDKRLLNKAKHVADFILR-----------SFDTPNRIPI--LKYFWKSDLRNRF 296

Query: 657 ITSTAGGGTLT---LEFGVLSRLTN-NTVFEQVTK 749
              T   G LT   L F  LS+LT  N  F+ V +
Sbjct: 297 PDRTVPSGQLTTMALAFIRLSQLTRLNKYFDAVER 331

>Q3M6Y1:CRCB_ANAVT Protein crcB homolog - Anabaena variabilis (strain ATCC 29413 / PCC|
           7937)
          Length = 137

 Score = 33.1 bits (74), Expect = 5.3
 Identities = 15/35 (42%), Positives = 18/35 (51%)
 Frame = +3

Query: 306 LGGYALTLIDSLDTLALLGDKERFAAGVEWVGKNV 410
           LG Y      +LDT  LLGD+   AAG  W G  +
Sbjct: 81  LGAYTTFSTYALDTFTLLGDRNLVAAGFYWAGSTI 115

>P53185:MTC2_YEAST Protein MTC2 - Saccharomyces cerevisiae (Baker's yeast)|
          Length = 909

 Score = 32.3 bits (72), Expect = 9.1
 Identities = 21/68 (30%), Positives = 34/68 (50%)
 Frame = +3

Query: 639 DDDESKITSTAGGGTLTLEFGVLSRLTNNTVFEQVTKNSVRGIWARRSKLNLVGAHINVF 818
           D+DE   T+T G    ++ FGVLS L+    FE++T N    +     KL L    + ++
Sbjct: 131 DNDEETATTTDGD---SMNFGVLSLLSIVQNFEEITPNLFEFL-----KLGLRSTLLKIW 182

Query: 819 TGEWTQKD 842
             +W + D
Sbjct: 183 VAQWQRYD 190


  Database: uniprot_sprot.fasta.out
    Posted date:  Jul 19, 2007  5:58 PM
  Number of letters in database: 100,686,439
  Number of sequences in database:  274,295
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 274295
Number of Hits to DB: 418,952,265
Number of extensions: 9378437
Number of successful extensions: 22962
Number of sequences better than 10.0: 25
Number of HSP's gapped: 22862
Number of HSP's successfully gapped: 35
Length of query: 781
Length of database: 100,686,439
Length adjustment: 121
Effective length of query: 660
Effective length of database: 67,496,744
Effective search space: 44547851040
Effective search space used: 44547851040
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)