>P49020:TMED2_CRIGR Transmembrane emp24 domain-containing protein 2 precursor -|
           Cricetulus griseus (Chinese hamster)
          Length = 196
 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 51/197 (25%), Positives = 94/197 (47%), Gaps = 5/197 (2%)
 Frame = +2

Query: 221 VLCIMPFLHPAAAIRFV-IDR--EECFSHNVEYEGDTVHVSFVVIKADTPWHYSEDGVDL 391
           VL ++  L   A+  FV ID   EECF   V   G  + + F V +      + +  V++
Sbjct: 2   VLVLLAALLATASGYFVSIDAHAEECFFERVT-SGTKMGLIFEVAEGG----FLDIDVEI 56

Query: 392 VVKDSNGAQVRDSRDKTSDKFEFIVQKRGVHRFCFTNK--SPYHETIDFDVHVGHYSYFD 565
              D+ G    D   ++S K+ F     G ++FCF+N+  +   + + F + +G      
Sbjct: 57  TGPDNKGIYKGDR--ESSGKYTFAAHMDGTYKFCFSNRMSTMTPKIVMFTIDIGEAPKGQ 114

Query: 566 QHAKDEHFSPLFEQIAKLDEALYNIQFEQHWLEAQTDRQAILNENMSRRAIHKALFESAA 745
               + H + L E I +L  A+  ++ EQ ++E +      +N+N + R +  + FE+  
Sbjct: 115 DMETEAHQNKLEEMINELAVAMTAVKHEQEYMEVRERIHRAINDNTNSRVVLWSFFEALV 174

Query: 746 LITASVIQVYLLRRLFE 796
           L+  ++ Q+Y L+R FE
Sbjct: 175 LVAMTLGQIYYLKRFFE 191

>Q63524:TMED2_RAT Transmembrane emp24 domain-containing protein 2 precursor - Rattus|
           norvegicus (Rat)
          Length = 201

 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 43/174 (24%), Positives = 83/174 (47%), Gaps = 2/174 (1%)
 Frame = +2

Query: 281 EECFSHNVEYEGDTVHVSFVVIKADTPWHYSEDGVDLVVKDSNGAQVRDSRDKTSDKFEF 460
           EECF   V   G  + + F V +      + +  V++   D+ G    D   ++S K+ F
Sbjct: 30  EECFFERVT-SGTKMGLIFEVAEGG----FLDIDVEITGPDNKGIYKGDR--ESSGKYTF 82

Query: 461 IVQKRGVHRFCFTNK--SPYHETIDFDVHVGHYSYFDQHAKDEHFSPLFEQIAKLDEALY 634
                G ++FCF+N+  +   + + F + +G          + H + L E I +L  A+ 
Sbjct: 83  AAHMDGTYKFCFSNRMSTMTPKIVMFTIDIGEAPKGQDMETEAHQNKLEEMINELAVAMT 142

Query: 635 NIQFEQHWLEAQTDRQAILNENMSRRAIHKALFESAALITASVIQVYLLRRLFE 796
            ++ EQ ++E +      +N+N + R +  + FE+  L+  ++ Q+Y L+R FE
Sbjct: 143 AVKHEQEYMEVRERIHRAINDNTNSRVVLWSFFEALVLVAMTLGQIYYLKRFFE 196

>Q9R0Q3:TMED2_MOUSE Transmembrane emp24 domain-containing protein 2 precursor - Mus|
           musculus (Mouse)
          Length = 201

 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 43/174 (24%), Positives = 83/174 (47%), Gaps = 2/174 (1%)
 Frame = +2

Query: 281 EECFSHNVEYEGDTVHVSFVVIKADTPWHYSEDGVDLVVKDSNGAQVRDSRDKTSDKFEF 460
           EECF   V   G  + + F V +      + +  V++   D+ G    D   ++S K+ F
Sbjct: 30  EECFFERVT-SGTKMGLIFEVAEGG----FLDIDVEITGPDNKGIYKGDR--ESSGKYTF 82

Query: 461 IVQKRGVHRFCFTNK--SPYHETIDFDVHVGHYSYFDQHAKDEHFSPLFEQIAKLDEALY 634
                G ++FCF+N+  +   + + F + +G          + H + L E I +L  A+ 
Sbjct: 83  AAHMDGTYKFCFSNRMSTMTPKIVMFTIDIGEAPKGQDMETEAHQNKLEEMINELAVAMT 142

Query: 635 NIQFEQHWLEAQTDRQAILNENMSRRAIHKALFESAALITASVIQVYLLRRLFE 796
            ++ EQ ++E +      +N+N + R +  + FE+  L+  ++ Q+Y L+R FE
Sbjct: 143 AVKHEQEYMEVRERIHRAINDNTNSRVVLWSFFEALVLVAMTLGQIYYLKRFFE 196

>Q15363:TMED2_HUMAN Transmembrane emp24 domain-containing protein 2 precursor - Homo|
           sapiens (Human)
          Length = 201

 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 43/174 (24%), Positives = 83/174 (47%), Gaps = 2/174 (1%)
 Frame = +2

Query: 281 EECFSHNVEYEGDTVHVSFVVIKADTPWHYSEDGVDLVVKDSNGAQVRDSRDKTSDKFEF 460
           EECF   V   G  + + F V +      + +  V++   D+ G    D   ++S K+ F
Sbjct: 30  EECFFERVT-SGTKMGLIFEVAEGG----FLDIDVEITGPDNKGIYKGDR--ESSGKYTF 82

Query: 461 IVQKRGVHRFCFTNK--SPYHETIDFDVHVGHYSYFDQHAKDEHFSPLFEQIAKLDEALY 634
                G ++FCF+N+  +   + + F + +G          + H + L E I +L  A+ 
Sbjct: 83  AAHMDGTYKFCFSNRMSTMTPKIVMFTIDIGEAPKGQDMETEAHQNKLEEMINELAVAMT 142

Query: 635 NIQFEQHWLEAQTDRQAILNENMSRRAIHKALFESAALITASVIQVYLLRRLFE 796
            ++ EQ ++E +      +N+N + R +  + FE+  L+  ++ Q+Y L+R FE
Sbjct: 143 AVKHEQEYMEVRERIHRAINDNTNSRVVLWSFFEALVLVAMTLGQIYYLKRFFE 196

>Q9Y3B3:TMED7_HUMAN Transmembrane emp24 domain-containing protein 7 precursor - Homo|
           sapiens (Human)
          Length = 224

 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 58/216 (26%), Positives = 106/216 (49%), Gaps = 9/216 (4%)
 Frame = +2

Query: 200 WTRACVLVLCIMPFLHPAAAIRFVI--DREECFSHNVEYEGDTVHVSFVVIKADTPWHYS 373
           W    + +L ++P    A+ I F +  + ++CF  ++  +G    + F VI   T  HY 
Sbjct: 17  WGCRLLALLLLVPGPGGASEITFELPDNAKQCFYEDIA-QGTKCTLEFQVI---TGGHYD 72

Query: 374 EDGVDLVVKDSNGAQVRDSRDKTSDKFEFIVQKRGVHRFCFTNK--SPYHETIDFDVHVG 547
              VD  ++D +G  +     K  D F F   K G ++FCF+N+  +  H+T+ FD  VG
Sbjct: 73  ---VDCRLEDPDGKVLYKEMKKQYDSFTFTASKNGTYKFCFSNEFSTFTHKTVYFDFQVG 129

Query: 548 H-YSYFDQHAKDEHFSPLFEQIAKLDEALYN-IQFEQHW--LEAQTDRQAILNENMSRRA 715
                F    +    + +      + EAL + I ++ H+   EAQ   +A   E+++ R 
Sbjct: 130 EDPPLFPSENRVSALTQMESACVSIHEALKSVIDYQTHFRLREAQGRSRA---EDLNTRV 186

Query: 716 IHKALFESAALITASVIQVYLLRRLF-ERKLGTSRV 820
            + ++ E+  L+  S+ QV+LL+  F +++  T+RV
Sbjct: 187 AYWSVGEALILLVVSIGQVFLLKSFFSDKRTTTTRV 222

>O17528:SEL9_CAEEL Suppressor/enhancer of lin-12 protein 9 precursor - Caenorhabditis|
           elegans
          Length = 203

 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 55/217 (25%), Positives = 98/217 (45%), Gaps = 13/217 (5%)
 Frame = +2

Query: 185 MEGLSWTRACVLVLCIMPFLHPAAAIRFVID--REECFSHNVEYEGDTVHVSFVVIKADT 358
           M  L+W  A +       F+ PAA+    +D   E+CF   +   G  + + F V     
Sbjct: 1   MNSLTWILAVL-------FVTPAASYFIHVDANEEQCFFDRLT-SGTKMGLMFEV----- 47

Query: 359 PWHYSEDG---VDLVVKDSNGAQVRDSRDKTSDKFEFIVQKRGVHRFCFTNK----SPYH 517
               +E G   +D+ +   +  ++     ++S KF F     GV+ +CF NK    +P  
Sbjct: 48  ----AEGGFLDIDVKITGPDNKEIYKGERESSGKFTFAAHMDGVYTYCFGNKMSTMTPKA 103

Query: 518 ETIDFDVHVGHY----SYFDQHAKDEHFSPLFEQIAKLDEALYNIQFEQHWLEAQTDRQA 685
                ++   H     +  +Q A D   + L E + +L  AL +++ EQ ++E +     
Sbjct: 104 VMFTVEITEPHQQAPGAAANQDAADN--AKLEEMVRELSSALMSVKHEQEYMEVRERVHR 161

Query: 686 ILNENMSRRAIHKALFESAALITASVIQVYLLRRLFE 796
            +NEN + R +  A FE+  L+  +V Q++ L+R FE
Sbjct: 162 NINENTNSRVVMWAAFEAFVLVGMTVGQIFYLKRFFE 198

>Q78IS1:TMED3_MOUSE Transmembrane emp24 domain-containing protein 3 precursor - Mus|
           musculus (Mouse)
          Length = 221

 Score = 57.4 bits (137), Expect = 9e-08
 Identities = 49/183 (26%), Positives = 81/183 (44%), Gaps = 4/183 (2%)
 Frame = +2

Query: 281 EECFSHNVEYEGDTVHVSFVVIKADTPWHYSEDGVDLVVKDSNGAQVRDSRDKTSDKFEF 460
           ++CF   VE +G    + + VI   T  HY    VD  V+D  G  +     K  D F +
Sbjct: 42  KQCFHEEVE-QGVKFSLDYQVI---TGGHYD---VDCYVEDPRGNVIYRETKKQYDSFTY 94

Query: 461 IVQKRGVHRFCFTNK--SPYHETIDFDVHVGHYSYF--DQHAKDEHFSPLFEQIAKLDEA 628
             + +GV+RFCF+N+  +  H+T+ FD  VG       D   +    + +      + EA
Sbjct: 95  KTEAKGVYRFCFSNEFSTFSHKTVYFDFQVGDEPPILPDMGNRVTALTQMESACVTIHEA 154

Query: 629 LYNIQFEQHWLEAQTDRQAILNENMSRRAIHKALFESAALITASVIQVYLLRRLFERKLG 808
           L  +   Q     +  +     E+++ R  + ++ E+ AL   S  QV LL+  F  K  
Sbjct: 155 LKTVIDSQTHYRLREAQDRARAEDLNSRVSYWSVGETIALFVVSFSQVLLLKSFFTEKRP 214

Query: 809 TSR 817
            +R
Sbjct: 215 VNR 217

>Q9Y3Q3:TMED3_HUMAN Transmembrane emp24 domain-containing protein 3 precursor - Homo|
           sapiens (Human)
          Length = 217

 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 49/183 (26%), Positives = 81/183 (44%), Gaps = 4/183 (2%)
 Frame = +2

Query: 281 EECFSHNVEYEGDTVHVSFVVIKADTPWHYSEDGVDLVVKDSNGAQVRDSRDKTSDKFEF 460
           ++CF   VE +G    + + VI   T  HY    VD  V+D  G  +     K  D F +
Sbjct: 38  KQCFHEEVE-QGVKFSLDYQVI---TGGHYD---VDCYVEDPQGNTIYRETKKQYDSFTY 90

Query: 461 IVQKRGVHRFCFTNK--SPYHETIDFDVHVGHYSYF--DQHAKDEHFSPLFEQIAKLDEA 628
             + +GV++FCF+N+  +  H+T+ FD  VG       D   +    + +      + EA
Sbjct: 91  RAEVKGVYQFCFSNEFSTFSHKTVYFDFQVGDEPPILPDMGNRVTALTQMESACVTIHEA 150

Query: 629 LYNIQFEQHWLEAQTDRQAILNENMSRRAIHKALFESAALITASVIQVYLLRRLFERKLG 808
           L  +   Q     +  +     E+++ R  + ++ E+ AL   S  QV LL+  F  K  
Sbjct: 151 LKTVIDSQTHYRLREAQDRARAEDLNSRVSYWSVGETIALFVVSFSQVLLLKSFFTEKRP 210

Query: 809 TSR 817
            SR
Sbjct: 211 ISR 213

>Q6AY25:TMED3_RAT Transmembrane emp24 domain-containing protein 3 precursor - Rattus|
           norvegicus (Rat)
          Length = 221

 Score = 55.5 bits (132), Expect = 3e-07
 Identities = 49/183 (26%), Positives = 81/183 (44%), Gaps = 4/183 (2%)
 Frame = +2

Query: 281 EECFSHNVEYEGDTVHVSFVVIKADTPWHYSEDGVDLVVKDSNGAQVRDSRDKTSDKFEF 460
           ++CF   VE +G    + + VI   T  HY    VD  V+D  G  +     K  D F +
Sbjct: 42  KQCFHEEVE-QGVKFSLDYQVI---TGGHYD---VDCYVEDPMGNIIYRETKKQYDSFTY 94

Query: 461 IVQKRGVHRFCFTNK--SPYHETIDFDVHVGHYSYF--DQHAKDEHFSPLFEQIAKLDEA 628
             + +GV+RFCF+N+  +  H+T+ FD  VG       D   +    + +      + EA
Sbjct: 95  KTEVKGVYRFCFSNEFSTFSHKTVYFDFQVGDEPPILPDMGNRVTALTQMESACVTIHEA 154

Query: 629 LYNIQFEQHWLEAQTDRQAILNENMSRRAIHKALFESAALITASVIQVYLLRRLFERKLG 808
           L  +   Q     +  +     E+++ R  + ++ E+ AL   S  QV LL+  F  K  
Sbjct: 155 LKTVIDSQTHYRLREAQDRARAEDLNSRVSYWSVGETIALFVVSFSQVLLLKSFFTEKRP 214

Query: 809 TSR 817
            +R
Sbjct: 215 INR 217

>Q90515:TMEDA_FUGRU Transmembrane emp24 domain-containing protein 10 precursor - Fugu|
           rubripes (Japanese pufferfish) (Takifugu rubripes)
          Length = 213

 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 39/165 (23%), Positives = 74/165 (44%), Gaps = 4/165 (2%)
 Frame = +2

Query: 320 TVHVSFVVIKADTPWHYSEDGVDLVVKDSNGAQVRDSRDKTSDKFEFIVQKRGVHRFCFT 499
           TVH S  V+          DG    + DS+   +    D T  KF F  +   +   CF 
Sbjct: 54  TVHTSSTVVG---------DGSIFKITDSSSHTLYSKEDATKGKFAFTTEDYDMFEVCFE 104

Query: 500 NKSPYH---ETIDFDVHVG-HYSYFDQHAKDEHFSPLFEQIAKLDEALYNIQFEQHWLEA 667
           +K       + ++ D+  G     +++ AK E   PL  ++ +L++   +I  +  +++ 
Sbjct: 105 SKCTGRVPDQLVNLDMKHGVEAKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKK 164

Query: 668 QTDRQAILNENMSRRAIHKALFESAALITASVIQVYLLRRLFERK 802
           + +     NE+ + R ++ ++F    LI  +  QV+ LRR F+ K
Sbjct: 165 REEEMRDTNESTNTRVLYFSIFSMFCLIGLATWQVFYLRRFFKAK 209

>Q5RE32:TMEDA_PONPY Transmembrane emp24 domain-containing protein 10 precursor - Pongo|
           pygmaeus (Orangutan)
          Length = 219

 Score = 51.2 bits (121), Expect = 6e-06
 Identities = 35/142 (24%), Positives = 66/142 (46%), Gaps = 4/142 (2%)
 Frame = +2

Query: 389 LVVKDSNGAQVRDSRDKTSDKFEFIVQKRGVHRFCFTNKSPYH---ETIDFDVHVG-HYS 556
           L + DS G  +    D T  KF F  +   +   CF +K       + +  D+  G    
Sbjct: 74  LKITDSAGHILYSKEDATKGKFAFTTEDYDMFEVCFESKGTGRIPDQLVILDMKHGVEAK 133

Query: 557 YFDQHAKDEHFSPLFEQIAKLDEALYNIQFEQHWLEAQTDRQAILNENMSRRAIHKALFE 736
            +++ AK E   PL  ++ +L++   +I  +  ++E + +     NE+ + R ++ ++F 
Sbjct: 134 NYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMEKREEEMRDTNESTNTRVLYFSIFS 193

Query: 737 SAALITASVIQVYLLRRLFERK 802
              LI  +  QV+ LRR F+ K
Sbjct: 194 MFCLIGLATWQVFYLRRFFKAK 215

>P49755:TMEDA_HUMAN Transmembrane emp24 domain-containing protein 10 precursor - Homo|
           sapiens (Human)
          Length = 219

 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 34/142 (23%), Positives = 66/142 (46%), Gaps = 4/142 (2%)
 Frame = +2

Query: 389 LVVKDSNGAQVRDSRDKTSDKFEFIVQKRGVHRFCFTNKSPYH---ETIDFDVHVG-HYS 556
           L + DS G  +    D T  KF F  +   +   CF +K       + +  D+  G    
Sbjct: 74  LKITDSAGHILYSKEDATKGKFAFTTEDYDMFEVCFESKGTGRIPDQLVILDMKHGVEAK 133

Query: 557 YFDQHAKDEHFSPLFEQIAKLDEALYNIQFEQHWLEAQTDRQAILNENMSRRAIHKALFE 736
            +++ AK E   PL  ++ +L++   +I  +  +++ + +     NE+ + R ++ ++F 
Sbjct: 134 NYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSIFS 193

Query: 737 SAALITASVIQVYLLRRLFERK 802
              LI  +  QV+ LRR F+ K
Sbjct: 194 MFCLIGLATWQVFYLRRFFKAK 215

>Q5E971:TMEDA_BOVIN Transmembrane emp24 domain-containing protein 10 precursor - Bos|
           taurus (Bovine)
          Length = 219

 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 34/142 (23%), Positives = 66/142 (46%), Gaps = 4/142 (2%)
 Frame = +2

Query: 389 LVVKDSNGAQVRDSRDKTSDKFEFIVQKRGVHRFCFTNKSPYH---ETIDFDVHVG-HYS 556
           L + DS G  +    D T  KF F  +   +   CF +K       + +  D+  G    
Sbjct: 74  LKITDSAGHILYSKEDATKGKFAFTTEDYDMFEVCFESKGTGRIPDQLVILDMKHGVEAK 133

Query: 557 YFDQHAKDEHFSPLFEQIAKLDEALYNIQFEQHWLEAQTDRQAILNENMSRRAIHKALFE 736
            +++ AK E   PL  ++ +L++   +I  +  +++ + +     NE+ + R ++ ++F 
Sbjct: 134 NYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSIFS 193

Query: 737 SAALITASVIQVYLLRRLFERK 802
              LI  +  QV+ LRR F+ K
Sbjct: 194 MFCLIGLATWQVFYLRRFFKAK 215

>Q6C503:ERV25_YARLI Endoplasmic reticulum vesicle protein 25 precursor - Yarrowia|
           lipolytica (Candida lipolytica)
          Length = 211

 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 46/207 (22%), Positives = 92/207 (44%), Gaps = 8/207 (3%)
 Frame = +2

Query: 206 RACVLVLCIMPFLHPAAAIRFVIDREECFSHNVEYEGDTVHVSFVVIKADTPWHYSEDGV 385
           ++ V VL ++  ++  AA+RFV+  ++             +   VV+  ++P +     +
Sbjct: 2   KSIVSVLTLLLLINAVAALRFVLPAKDKNELPFCVRDFVKNGELVVVTVESPKYADGQQL 61

Query: 386 DLVVKDSNGAQVRDSRDKTSDKFE-FIVQKRGVHRFCFTNKSPYHET------IDFDVHV 544
            +VV+D++G +    ++    +   F   +      CF N +  H+       ID  V +
Sbjct: 62  SVVVRDAHGNEYTRIKNVLGREITTFSSHQDTALDVCFHNVANSHQDLGKTKEIDLSVAI 121

Query: 545 GHYSY-FDQHAKDEHFSPLFEQIAKLDEALYNIQFEQHWLEAQTDRQAILNENMSRRAIH 721
           G  +  ++Q    E   P   Q+ K++E +  +  E ++L+ +  R    NE+ +RR   
Sbjct: 122 GANARDWEQIQASEKLKPAEVQLRKIEEIVDEVDKEMNYLKMREIRLRDTNESTNRRVKF 181

Query: 722 KALFESAALITASVIQVYLLRRLFERK 802
            ++  + ALI   V Q+  LR  F  K
Sbjct: 182 FSVGITLALIALGVWQIIYLRSYFRSK 208

>O35587:TMEDA_MESAU Transmembrane protein Tmp21 precursor - Mesocricetus auratus|
           (Golden hamster)
          Length = 219

 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 34/142 (23%), Positives = 66/142 (46%), Gaps = 4/142 (2%)
 Frame = +2

Query: 389 LVVKDSNGAQVRDSRDKTSDKFEFIVQKRGVHRFCFTNKSPYH---ETIDFDVHVG-HYS 556
           L + DS G  +    D T  KF F  +   +   CF +K       + +  D+  G    
Sbjct: 74  LKITDSAGHILYAKEDATKGKFAFTTEDYDMFEVCFESKGTGRIPDQLVILDMKHGVEAK 133

Query: 557 YFDQHAKDEHFSPLFEQIAKLDEALYNIQFEQHWLEAQTDRQAILNENMSRRAIHKALFE 736
            +++ AK E   PL  ++ +L++   +I  +  +++ + +     NE+ + R ++ ++F 
Sbjct: 134 NYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSIFS 193

Query: 737 SAALITASVIQVYLLRRLFERK 802
              LI  +  QV+ LRR F+ K
Sbjct: 194 MLCLIGLATWQVFYLRRFFKAK 215

>Q63584:TMEDA_RAT Transmembrane emp24 domain-containing protein 10 precursor - Rattus|
           norvegicus (Rat)
          Length = 219

 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 34/142 (23%), Positives = 66/142 (46%), Gaps = 4/142 (2%)
 Frame = +2

Query: 389 LVVKDSNGAQVRDSRDKTSDKFEFIVQKRGVHRFCFTNKSPYH---ETIDFDVHVG-HYS 556
           L + DS G  +    D T  KF F  +   +   CF +K       + +  D+  G    
Sbjct: 74  LKITDSAGHILYAKEDATKGKFAFTTEDYDMFEVCFESKGTGRIPDQLVILDMKHGVEAK 133

Query: 557 YFDQHAKDEHFSPLFEQIAKLDEALYNIQFEQHWLEAQTDRQAILNENMSRRAIHKALFE 736
            +++ AK E   PL  ++ +L++   +I  +  +++ + +     NE+ + R ++ ++F 
Sbjct: 134 NYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSIFS 193

Query: 737 SAALITASVIQVYLLRRLFERK 802
              LI  +  QV+ LRR F+ K
Sbjct: 194 MFCLIGLATWQVFYLRRFFKAK 215

>Q9D1D4:TMEDA_MOUSE Transmembrane emp24 domain-containing protein 10 precursor - Mus|
           musculus (Mouse)
          Length = 219

 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 34/142 (23%), Positives = 66/142 (46%), Gaps = 4/142 (2%)
 Frame = +2

Query: 389 LVVKDSNGAQVRDSRDKTSDKFEFIVQKRGVHRFCFTNKSPYH---ETIDFDVHVG-HYS 556
           L + DS G  +    D T  KF F  +   +   CF +K       + +  D+  G    
Sbjct: 74  LKITDSAGHILYAKEDATKGKFAFTTEDYDMFEVCFESKGTGRIPDQLVILDMKHGVEAK 133

Query: 557 YFDQHAKDEHFSPLFEQIAKLDEALYNIQFEQHWLEAQTDRQAILNENMSRRAIHKALFE 736
            +++ AK E   PL  ++ +L++   +I  +  +++ + +     NE+ + R ++ ++F 
Sbjct: 134 NYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSIFS 193

Query: 737 SAALITASVIQVYLLRRLFERK 802
              LI  +  QV+ LRR F+ K
Sbjct: 194 MFCLIGLATWQVFYLRRFFKAK 215

>Q6CWW7:ERV25_KLULA Endoplasmic reticulum vesicle protein 25 precursor - Kluyveromyces|
           lactis (Yeast) (Candida sphaerica)
          Length = 212

 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 49/210 (23%), Positives = 93/210 (44%), Gaps = 12/210 (5%)
 Frame = +2

Query: 209 ACVLVLCIMPFLHPAAAIRFVIDR----EECFSHNVEYEGDTVHVSFVVIKADTPWHYSE 376
           ACVL+LC + F     A+RF I      E+    +   EG       V+I  +T     +
Sbjct: 6   ACVLLLCAL-FFEQVFAVRFDIPASTKPEQVCIRDFVSEGQ-----LVLIDIETDGSVGD 59

Query: 377 -DGVDLVVKDSNGAQVRDSRDKTSD-KFEFIVQKRGVHRFCFTNKSPYH-----ETIDFD 535
              ++L V+DSNG + R +RD   + +  F   +      CF N +  +      +I+ D
Sbjct: 60  GQQLNLYVRDSNGNEYRRNRDIAGEVRVVFTAPQSTSFDVCFENVAQVNGRSLSRSIELD 119

Query: 536 VHVGHYSY-FDQHAKDEHFSPLFEQIAKLDEALYNIQFEQHWLEAQTDRQAILNENMSRR 712
           +  G  +  +++    E   P+  ++ +++E    I  E ++L+ + +R    NE+ +RR
Sbjct: 120 IESGSEARDWNKIQASEKLKPVEVELRRIEELTDEIVDEFNYLKGREERLRDTNESTNRR 179

Query: 713 AIHKALFESAALITASVIQVYLLRRLFERK 802
             + ++     L+     QV  ++  F  K
Sbjct: 180 VRNFSIAVIVVLVALGAWQVNYMKNFFRAK 209

>Q28735:TMEDA_RABIT Transmembrane emp24 domain-containing protein 10 precursor -|
           Oryctolagus cuniculus (Rabbit)
          Length = 219

 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 33/142 (23%), Positives = 66/142 (46%), Gaps = 4/142 (2%)
 Frame = +2

Query: 389 LVVKDSNGAQVRDSRDKTSDKFEFIVQKRGVHRFCFTNKSPYH---ETIDFDVHVG-HYS 556
           L + DS G  +    D +  KF F  +   +   CF +K       + +  D+  G    
Sbjct: 74  LKITDSAGHILYSKEDASKGKFAFTTEDYDMFEVCFESKGTGRIPDQLVILDMKHGVEAK 133

Query: 557 YFDQHAKDEHFSPLFEQIAKLDEALYNIQFEQHWLEAQTDRQAILNENMSRRAIHKALFE 736
            +++ AK E   PL  ++ +L++   +I  +  +++ + +     NE+ + R ++ ++F 
Sbjct: 134 NYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSIFS 193

Query: 737 SAALITASVIQVYLLRRLFERK 802
              LI  +  QV+ LRR F+ K
Sbjct: 194 MFCLIGLATWQVFYLRRFFKAK 215

>P32803:EMP24_YEAST Endosomal protein P24B precursor - Saccharomyces cerevisiae|
           (Baker's yeast)
          Length = 203

 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 39/193 (20%), Positives = 79/193 (40%)
 Frame = +2

Query: 218 LVLCIMPFLHPAAAIRFVIDREECFSHNVEYEGDTVHVSFVVIKADTPWHYSEDGVDLVV 397
           ++ C + F   A  +        CF  ++  +GD + +SF     +        G  ++ 
Sbjct: 9   VIACFLFFSASAHNVLLPAYGRRCFFEDLS-KGDELSISFQFGDRNPQSSSQLTGDFIIY 67

Query: 398 KDSNGAQVRDSRDKTSDKFEFIVQKRGVHRFCFTNKSPYHETIDFDVHVGHYSYFDQHAK 577
                  ++  RD +  +       +G  ++CF N++   ET D   ++    Y D    
Sbjct: 68  GPERHEVLKTVRDTSHGEITLSAPYKGHFQYCFLNENTGIETKDVTFNIHGVVYVD--LD 125

Query: 578 DEHFSPLFEQIAKLDEALYNIQFEQHWLEAQTDRQAILNENMSRRAIHKALFESAALITA 757
           D + + L   + KL +    ++ EQ ++  +        E+ + R    ++F+   +I  
Sbjct: 126 DPNTNTLDSAVRKLSKLTREVKDEQSYIVIRERTHRNTAESTNDRVKWWSIFQLGVVIAN 185

Query: 758 SVIQVYLLRRLFE 796
           S+ Q+Y LRR FE
Sbjct: 186 SLFQIYYLRRFFE 198

>Q4P958:ERV25_USTMA Endoplasmic reticulum vesicle protein 25 precursor - Ustilago|
           maydis (Smut fungus)
          Length = 224

 Score = 45.1 bits (105), Expect = 5e-04
 Identities = 44/173 (25%), Positives = 69/173 (39%), Gaps = 11/173 (6%)
 Frame = +2

Query: 317 DTVHVSFVVIKADTPWHYSEDGVDLVVKDS---NGAQVRDSRDKTSDKFEFIVQKRGVHR 487
           D++ +    + A  P+ +S   VD+ V D    N   +     K   +            
Sbjct: 48  DSLVIVTASVVAKEPFDFSHQRVDIEVVDGSQHNNVYLSKKAIKGETRLAINTHSHADLG 107

Query: 488 FCFTNKSPYHE-------TIDFDVHVGHYSY-FDQHAKDEHFSPLFEQIAKLDEALYNIQ 643
            CF N             TID DV +G  +  ++  A  E  S L  ++ KL+     I 
Sbjct: 108 VCFKNTLTSKSGNQIPVVTIDLDVDIGADAVDYNAIANQESLSGLETEMRKLEAVANEIV 167

Query: 644 FEQHWLEAQTDRQAILNENMSRRAIHKALFESAALITASVIQVYLLRRLFERK 802
            E  +L+ +  R A  N + + R  + A+    ALI   V QV+ LR  F+RK
Sbjct: 168 NEMEYLKKRELRMADTNLSTNMRVTNFAILTLIALIALGVWQVFHLRGFFKRK 220

>O13770:YE98_SCHPO Uncharacterized protein C17A5.08 precursor - Schizosaccharomyces|
           pombe (Fission yeast)
          Length = 210

 Score = 42.0 bits (97), Expect = 0.004
 Identities = 38/202 (18%), Positives = 86/202 (42%), Gaps = 8/202 (3%)
 Frame = +2

Query: 218 LVLCIMPFLHPAAAIRFVIDREE--CFSHNVEYEGDTVHVSFVVIKADTPWHYSEDGVDL 391
           + L ++  L  A  + F ++ +E  C+  +  + G+  H ++ V    +        VD 
Sbjct: 9   ITLFLLASLASAIELTFKLENQEKQCYYLDSFHTGEKTHFTYAVQSGGS------FDVDY 62

Query: 392 VVKDSNGAQVRDSRDKTSDKFEFIVQKRGVHRFCFTNK-SPYHETI-----DFDVHVGHY 553
           ++K  +   V   + +      F ++++G + FCF N  S + + I       +  +   
Sbjct: 63  MIKAPSQKTVALGKKRRQADVFFTLEEKGEYEFCFDNHMSTFTDKIVTMEITMENELSLP 122

Query: 554 SYFDQHAKDEHFSPLFEQIAKLDEALYNIQFEQHWLEAQTDRQAILNENMSRRAIHKALF 733
           +     AKD     +   + ++  AL  I   Q++ + +  R     ++   R    +L 
Sbjct: 123 ALTRDEAKDYKKDSMQSTVLEISTALSEIDRVQNYFKTREHRNYSTVKSTQARIFWFSLA 182

Query: 734 ESAALITASVIQVYLLRRLFER 799
           ES  ++  S +QV++++  F+R
Sbjct: 183 ESIMVVALSALQVFIVKTFFKR 204

>P56474:UVRA_HELPY UvrABC system protein A - Helicobacter pylori (Campylobacter|
           pylori)
          Length = 935

 Score = 37.0 bits (84), Expect = 0.12
 Identities = 21/56 (37%), Positives = 33/56 (58%), Gaps = 2/56 (3%)
 Frame = +2

Query: 608 IAKLDEALYNIQFEQHWLEAQTDRQAILNENMSR--RAIHKALFESAALITASVIQ 769
           + +LDE ++  + ++H +EA  DR  + NEN SR   AI KAL ES   +   ++Q
Sbjct: 183 MVRLDEEIHLHKTKKHTIEAVVDRVVVNNENASRIASAIEKALKESYGELEVEILQ 238

>P38819:ERP5_YEAST Protein ERP5 precursor - Saccharomyces cerevisiae (Baker's yeast)|
          Length = 212

 Score = 35.4 bits (80), Expect = 0.36
 Identities = 27/135 (20%), Positives = 60/135 (44%), Gaps = 3/135 (2%)
 Frame = +2

Query: 407 NGAQVRDSRDKTSDKFEFIVQKRGVHRFCFT---NKSPYHETIDFDVHVGHYSYFDQHAK 577
           N  +V + ++  +    F     G HRFCFT   +K      +  ++ +G+    D   K
Sbjct: 76  NDHRVLNQKNSHTGDVTFTALDTGEHRFCFTPFYSKKSATLRVFIELEIGNVEALDS-KK 134

Query: 578 DEHFSPLFEQIAKLDEALYNIQFEQHWLEAQTDRQAILNENMSRRAIHKALFESAALITA 757
            E  + L  ++ +L + L +I+ EQ  +  +       +E+ + + +  ++F+   L+  
Sbjct: 135 KEDMNSLKGRVGQLTQRLSSIRKEQDAIREKEAEFRNQSESANSKIMTWSVFQLLILLGT 194

Query: 758 SVIQVYLLRRLFERK 802
              Q+  L+  F ++
Sbjct: 195 CAFQLRYLKNFFVKQ 209

>Q9ZLD6:UVRA_HELPJ UvrABC system protein A - Helicobacter pylori J99 (Campylobacter|
           pylori J99)
          Length = 941

 Score = 35.0 bits (79), Expect = 0.47
 Identities = 20/56 (35%), Positives = 33/56 (58%), Gaps = 2/56 (3%)
 Frame = +2

Query: 608 IAKLDEALYNIQFEQHWLEAQTDRQAILNENMSR--RAIHKALFESAALITASVIQ 769
           + +LDE ++  + ++H +EA  DR  I +EN SR   A+ KAL ES   +   ++Q
Sbjct: 189 MVRLDEEIHLHKTKKHTIEAVVDRVVINSENASRIASAVEKALKESYGELEVEILQ 244

>Q28BQ6:TMED1_XENTR Transmembrane emp24 domain-containing protein 1 precursor - Xenopus|
           tropicalis (Western clawed frog) (Silurana tropicalis)
          Length = 220

 Score = 32.7 bits (73), Expect = 2.3
 Identities = 48/208 (23%), Positives = 81/208 (38%), Gaps = 18/208 (8%)
 Frame = +2

Query: 233 MPFLHPAAAIRFVIDREECFSHNVEYEGDTVHVSFVVIKADTPWHYSEDGVDLVVKDSNG 412
           + FL PA        R+ECF     Y G ++ + + VI        +   VD  V   +G
Sbjct: 27  LTFLLPAG-------RQECFYQTTLYNG-SMEIEYQVIGG------AGLDVDFSVTTPSG 72

Query: 413 AQVRDSRDKTSDKFEFIVQKRGVHRFCFTNK-SPYHETIDFDVHVGHYSYFDQHAKDEHF 589
             +   R ++         + G +  CF N  S   E + F   +     FD    DE  
Sbjct: 73  ILLIMERRRSDGVHTVEPTEAGDYMICFDNSFSTISEKLVFFELI-----FDNQQGDEEP 127

Query: 590 SPLFEQIA-------KLDEALYNIQFEQHWLEAQTDRQAIL------NENMSRRAIHKAL 730
               + +        KL++   +I+  +  LE     Q +L      + N+    + +  
Sbjct: 128 DSWADVVEPDELLDIKLEDIKESIESVKSRLERSIQMQTVLRAFEARDRNLQDSNLERVN 187

Query: 731 FESA----ALITASVIQVYLLRRLFERK 802
           F SA     L+T + +QVY+L+ LF+ K
Sbjct: 188 FWSAINVGVLVTVAFLQVYMLKSLFDDK 215

>Q13319:CD5R2_HUMAN Cyclin-dependent kinase 5 activator 2 precursor - Homo sapiens|
           (Human)
          Length = 367

 Score = 32.3 bits (72), Expect = 3.1
 Identities = 21/73 (28%), Positives = 28/73 (38%), Gaps = 4/73 (5%)
 Frame = -3

Query: 267 KRIAAAGCRNGIMQRTKTQALVQLSPSMIYQQRSNSRSYRASQLPPAGGRRRNRCWRPAP 88
           KR+ AA  +     +  T       P  + QQR+     R  + PP GG        P P
Sbjct: 67  KRLVAASAKKKKGSKKVTPKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKPLAVPVP 126

Query: 87  VLPGGA----PPS 61
            +P  A    PPS
Sbjct: 127 TVPAAAATCEPPS 139

>Q08977:YP260_YEAST Uncharacterized protein YPL260W - Saccharomyces cerevisiae (Baker's|
           yeast)
          Length = 551

 Score = 32.0 bits (71), Expect = 4.0
 Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
 Frame = +2

Query: 578 DEHFSPLFEQIAKLDEALYNIQFEQHWLEAQTD---RQAILNENMSRRAIHKALFESAAL 748
           D +  P++EQ+  +   L N+   + W   +TD    Q  LNE  ++R   K   +S   
Sbjct: 342 DPYLQPIYEQLIDIKTTLENLMITRRWTLRETDLFSYQKKLNEIDNKRINGKFPTKSQDS 401

Query: 749 ITASVIQVYLLRRLF 793
              S++ +YLLRR +
Sbjct: 402 KGQSIL-LYLLRRCY 415

>Q9HNS3:GLPB_HALSA Probable anaerobic glycerol-3-phosphate dehydrogenase subunit B -|
           Halobacterium salinarium (Halobacterium halobium)
          Length = 427

 Score = 31.6 bits (70), Expect = 5.2
 Identities = 27/100 (27%), Positives = 48/100 (48%), Gaps = 5/100 (5%)
 Frame = +2

Query: 302 VEYEGDTVHVSFVVIKADTPWHYSEDGVDLVVKDSNGAQVRDSRDKTSDKFEFIVQKRG- 478
           +E  G  +     V+ ADT    +  GV+ V  + NGA++ +S D      E+++   G 
Sbjct: 272 LEAAGVRIETGNPVVDADT----TAGGVETVYVEKNGARIPNSAD------EYVLATGGL 321

Query: 479 VHRFCFTNKSPYHETIDFDVHVGH----YSYFDQHAKDEH 586
           V +   +++   +E I FD  + H    Y++FD  A  +H
Sbjct: 322 VGKGIDSDRDAVYEPI-FDCRIAHSDDRYAWFDDDAFGDH 360

>Q8WXH0:SYNE2_HUMAN Nesprin-2 - Homo sapiens (Human)|
          Length = 6885

 Score = 31.2 bits (69), Expect = 6.8
 Identities = 23/84 (27%), Positives = 38/84 (45%), Gaps = 6/84 (7%)
 Frame = +2

Query: 503  KSPYHETIDFDVHVG------HYSYFDQHAKDEHFSPLFEQIAKLDEALYNIQFEQHWLE 664
            +S  +E  +F  H+G      H  +   + K +H   L E I + +     IQ   +WLE
Sbjct: 5131 ESKRYERTEFAEHLGEMNRQWHRVHGMLNRKIQHLEQLLESITESEN---KIQILNNWLE 5187

Query: 665  AQTDRQAILNENMSRRAIHKALFE 736
            AQ +R   L +  S  ++ K L +
Sbjct: 5188 AQEERLKTLQKPESVISVQKLLLD 5211

>Q2KJ84:TMED5_BOVIN Transmembrane emp24 domain-containing protein 5 precursor - Bos|
           taurus (Bovine)
          Length = 226

 Score = 30.8 bits (68), Expect = 8.9
 Identities = 31/136 (22%), Positives = 52/136 (38%), Gaps = 14/136 (10%)
 Frame = +2

Query: 437 KTSDKFEFIVQKRGVHRFCFTN--KSPYHETIDFDVHVGHYSYFDQHAKD---------- 580
           + SD    I  + G + FCF N   +   + I F++ + +    +Q  +D          
Sbjct: 86  RKSDGVHTIETEVGDYMFCFDNTFSTISEKVIFFELILDNMGEQEQEQEDWKKYITGTDM 145

Query: 581 --EHFSPLFEQIAKLDEALYNIQFEQHWLEAQTDRQAILNENMSRRAIHKALFESAALIT 754
                  + E I  +   L      Q  L A   R   + E+   R    ++     ++ 
Sbjct: 146 LDMKLEDILESINSIKSRLSKSGHIQTLLRAFEARDRNIQESNFDRVNFWSMVNLVVMVV 205

Query: 755 ASVIQVYLLRRLFERK 802
            S IQVY+L+ LFE K
Sbjct: 206 VSAIQVYMLKSLFEDK 221

>P07003:POXB_ECOLI Pyruvate dehydrogenase [cytochrome] - Escherichia coli|
          Length = 572

 Score = 30.8 bits (68), Expect = 8.9
 Identities = 20/50 (40%), Positives = 26/50 (52%)
 Frame = +1

Query: 655 LARGPNRPASNIEREHEQEGHPQGTFRVGCAHYSQRHSSLSATPTLRAQA 804
           LA   + P+S I   + QE HPQ  FR  C+HY +  SS    P + A A
Sbjct: 96  LAIAAHIPSSEIGSGYFQETHPQELFR-ECSHYCELVSSPEQIPQVLAIA 144

>P11708:MDHC_PIG Malate dehydrogenase, cytoplasmic - Sus scrofa (Pig)|
          Length = 334

 Score = 30.8 bits (68), Expect = 8.9
 Identities = 18/59 (30%), Positives = 28/59 (47%), Gaps = 2/59 (3%)
 Frame = -1

Query: 620 LTLQFVQTKVKNVHLW--HADQNTNNVQHARRSLWFRDMGIYW*SRSDGHLSSEL*TQI 450
           L L      VKNV +W  H+     +V HA+  L  +++G+Y   + D  L  E  T +
Sbjct: 169 LKLGVTSDDVKNVIIWGNHSSTQYPDVNHAKVKLQAKEVGVYEAVKDDSWLKGEFITTV 227


  Database: uniprot_sprot.fasta.out
    Posted date:  Jul 19, 2007  5:58 PM
  Number of letters in database: 100,686,439
  Number of sequences in database:  274,295
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 274295
Number of Hits to DB: 180,079,540
Number of extensions: 4080959
Number of successful extensions: 11082
Number of sequences better than 10.0: 33
Number of HSP's gapped: 11073
Number of HSP's successfully gapped: 33
Length of query: 330
Length of database: 100,686,439
Length adjustment: 114
Effective length of query: 216
Effective length of database: 69,416,809
Effective search space: 14994030744
Effective search space used: 14994030744
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)