ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | FLbaf128p14 |
|---|---|
| Clone Library Name | barley_pub |
>P42158:KC1D_ARATH Casein kinase I isoform delta-like - Arabidopsis thaliana (Mouse-ear| cress) Length = 450 Score = 633 bits (1632), Expect = 0.0 Identities = 324/460 (70%), Positives = 375/460 (81%), Gaps = 3/460 (0%) Frame = +3 Query: 168 MEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQ 347 MEPRVGNK+RLGRK+GSGSFGEIYLGTN+ TNEE+AIKLENVKTKHPQLLYESKLYR+LQ Sbjct: 1 MEPRVGNKFRLGRKIGSGSFGEIYLGTNIHTNEELAIKLENVKTKHPQLLYESKLYRILQ 60 Query: 348 GGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIH 527 GGTG+ NVKWFGVEGDYNVLVMD+LGPSLEDLF+FC+RKLSLK+VLMLADQMINRVEF H Sbjct: 61 GGTGVPNVKWFGVEGDYNVLVMDLLGPSLEDLFNFCSRKLSLKSVLMLADQMINRVEFFH 120 Query: 528 SKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYA 707 SKSFLHRD+KPDNFLMGLG+RANQVY+IDFGLAKKYRD++THQHIPYRENKNLTGTARYA Sbjct: 121 SKSFLHRDLKPDNFLMGLGRRANQVYIIDFGLAKKYRDSTTHQHIPYRENKNLTGTARYA 180 Query: 708 SVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKISERKIATSIEAL 887 S++THLGIEQSRRDD+ESLGY+LMYFL+GSLPWQGLKAGTKKQKYE+ISE+K++TSIEAL Sbjct: 181 SMNTHLGIEQSRRDDLESLGYILMYFLKGSLPWQGLKAGTKKQKYERISEKKVSTSIEAL 240 Query: 888 CRGYPSEFQSFFHYCRSLRFEDSPDYQYLKRLFRDLFIREGFQFDYVFDWTILKYQQSQM 1067 CRGYPSEF S+FHYCRSLRF+D PDY YLKR+FRDLFIREGFQFDYVFDWTILKYQQSQ+ Sbjct: 241 CRGYPSEFASYFHYCRSLRFDDKPDYAYLKRIFRDLFIREGFQFDYVFDWTILKYQQSQL 300 Query: 1068 TSVPPRAIAAAAGQSSGMAPIASN-NRLSATEEGRISGWSADPTRSQVPPTGINAGSLSK 1244 T+ P RA+ A G S+ + P SN +R + EEGR + +R +V N+G++S Sbjct: 301 TAPPSRALNPAVGTSAALPPGISNIDRYTGEEEGRP---HMESSRRRVSGALDNSGNISN 357 Query: 1245 QKSPVRPDLSAPKEAVLSSSTFLGRSGVFSRR-PAVSSSRD-LPSSEAEPSRSRAPDVSP 1418 Q P S+ +++++ SS+ +S SRR AVS SRD P SE RSR DVS Sbjct: 358 Q-----PTSSSARDSMIPSSSLFAQSAGSSRRVTAVSGSRDNFPGSEELLQRSRTGDVSR 412 Query: 1419 GTFQRNSAPRRASHTLDYSDPRHKSISNNYESTIRGIQGL 1538 G RNS P A KS +YES ++GI L Sbjct: 413 GVIPRNS-PGEAG----------KSTRRHYESVVKGIDNL 441
>Q9JMK2:KC1E_MOUSE Casein kinase I isoform epsilon - Mus musculus (Mouse)| Length = 416 Score = 488 bits (1257), Expect = e-137 Identities = 238/366 (65%), Positives = 286/366 (78%), Gaps = 2/366 (0%) Frame = +3 Query: 168 MEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQ 347 ME RVGNKYRLGRK+GSGSFG+IYLG N+ + EEVAIKLE VKTKHPQL ESK Y+++Q Sbjct: 1 MELRVGNKYRLGRKIGSGSFGDIYLGANIASGEEVAIKLECVKTKHPQLHIESKFYKMMQ 60 Query: 348 GGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIH 527 GG GI ++KW G EGDYNV+VM++LGPSLEDLF+FC+RK SLKTVL+LADQMI+R+E+IH Sbjct: 61 GGVGIPSIKWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIH 120 Query: 528 SKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYA 707 SK+F+HRD+KPDNFLMGLGK+ N VY+IDFGLAKKYRD THQHIPYRENKNLTGTARYA Sbjct: 121 SKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA 180 Query: 708 SVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKISERKIATSIEAL 887 S++THLGIEQSRRDD+ESLGYVLMYF GSLPWQGLKA TK+QKYE+ISE+K++T IE L Sbjct: 181 SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL 240 Query: 888 CRGYPSEFQSFFHYCRSLRFEDSPDYQYLKRLFRDLFIREGFQFDYVFDWTILKYQQSQM 1067 C+GYPSEF ++ ++CRSLRF+D PDY YL++LFR+LF R+GF +DYVFDW +LK+ Sbjct: 241 CKGYPSEFSTYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKF----- 295 Query: 1068 TSVPPRAIAAAAGQSSGMAPIASNNRLSATEE--GRISGWSADPTRSQVPPTGINAGSLS 1241 G + + R EE G++ G SA PPTG A L Sbjct: 296 ------------GAARNPEDVDRERREHEREERMGQLRG-SATRALPPGPPTGATANRLR 342 Query: 1242 KQKSPV 1259 PV Sbjct: 343 SAAEPV 348
>P49674:KC1E_HUMAN Casein kinase I isoform epsilon - Homo sapiens (Human)| Length = 416 Score = 488 bits (1257), Expect = e-137 Identities = 238/366 (65%), Positives = 286/366 (78%), Gaps = 2/366 (0%) Frame = +3 Query: 168 MEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQ 347 ME RVGNKYRLGRK+GSGSFG+IYLG N+ + EEVAIKLE VKTKHPQL ESK Y+++Q Sbjct: 1 MELRVGNKYRLGRKIGSGSFGDIYLGANIASGEEVAIKLECVKTKHPQLHIESKFYKMMQ 60 Query: 348 GGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIH 527 GG GI ++KW G EGDYNV+VM++LGPSLEDLF+FC+RK SLKTVL+LADQMI+R+E+IH Sbjct: 61 GGVGIPSIKWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIH 120 Query: 528 SKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYA 707 SK+F+HRD+KPDNFLMGLGK+ N VY+IDFGLAKKYRD THQHIPYRENKNLTGTARYA Sbjct: 121 SKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA 180 Query: 708 SVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKISERKIATSIEAL 887 S++THLGIEQSRRDD+ESLGYVLMYF GSLPWQGLKA TK+QKYE+ISE+K++T IE L Sbjct: 181 SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL 240 Query: 888 CRGYPSEFQSFFHYCRSLRFEDSPDYQYLKRLFRDLFIREGFQFDYVFDWTILKYQQSQM 1067 C+GYPSEF ++ ++CRSLRF+D PDY YL++LFR+LF R+GF +DYVFDW +LK+ Sbjct: 241 CKGYPSEFSTYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKF----- 295 Query: 1068 TSVPPRAIAAAAGQSSGMAPIASNNRLSATEE--GRISGWSADPTRSQVPPTGINAGSLS 1241 G + + R EE G++ G SA PPTG A L Sbjct: 296 ------------GAARNPEDVDRERREHEREERMGQLRG-SATRALPPGPPTGATANRLR 342 Query: 1242 KQKSPV 1259 PV Sbjct: 343 SAAEPV 348
>Q06486:KC1D_RAT Casein kinase I isoform delta - Rattus norvegicus (Rat)| Length = 415 Score = 488 bits (1257), Expect = e-137 Identities = 239/377 (63%), Positives = 295/377 (78%) Frame = +3 Query: 168 MEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQ 347 ME RVGN+YRLGRK+GSGSFG+IYLGT++ EEVAIKLE VKTKHPQL ESK+Y+++Q Sbjct: 1 MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQ 60 Query: 348 GGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIH 527 GG GI ++W G EGDYNV+VM++LGPSLEDLF+FC+RK SLKTVL+LADQMI+R+E+IH Sbjct: 61 GGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIH 120 Query: 528 SKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYA 707 SK+F+HRD+KPDNFLMGLGK+ N VY+IDFGLAKKYRD THQHIPYRENKNLTGTARYA Sbjct: 121 SKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA 180 Query: 708 SVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKISERKIATSIEAL 887 S++THLGIEQSRRDD+ESLGYVLMYF GSLPWQGLKA TK+QKYE+ISE+K++T IE L Sbjct: 181 SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL 240 Query: 888 CRGYPSEFQSFFHYCRSLRFEDSPDYQYLKRLFRDLFIREGFQFDYVFDWTILKYQQSQM 1067 C+GYPSEF ++ ++CRSLRF+D PDY YL++LFR+LF R+GF +DYVFDW +LK+ S+ Sbjct: 241 CKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRA 300 Query: 1068 TSVPPRAIAAAAGQSSGMAPIASNNRLSATEEGRISGWSADPTRSQVPPTGINAGSLSKQ 1247 R + A+ L +T GR+ G T+ PPT + S + Sbjct: 301 ADDAERERRDREERLRHSRNPATRG-LPSTASGRLRG-----TQEVAPPTPLTPTSHTAN 354 Query: 1248 KSPVRPDLSAPKEAVLS 1298 SP RP +E +S Sbjct: 355 TSP-RPVSGMERERKVS 370
>Q9DC28:KC1D_MOUSE Casein kinase I isoform delta - Mus musculus (Mouse)| Length = 415 Score = 488 bits (1257), Expect = e-137 Identities = 239/377 (63%), Positives = 295/377 (78%) Frame = +3 Query: 168 MEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQ 347 ME RVGN+YRLGRK+GSGSFG+IYLGT++ EEVAIKLE VKTKHPQL ESK+Y+++Q Sbjct: 1 MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQ 60 Query: 348 GGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIH 527 GG GI ++W G EGDYNV+VM++LGPSLEDLF+FC+RK SLKTVL+LADQMI+R+E+IH Sbjct: 61 GGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIH 120 Query: 528 SKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYA 707 SK+F+HRD+KPDNFLMGLGK+ N VY+IDFGLAKKYRD THQHIPYRENKNLTGTARYA Sbjct: 121 SKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA 180 Query: 708 SVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKISERKIATSIEAL 887 S++THLGIEQSRRDD+ESLGYVLMYF GSLPWQGLKA TK+QKYE+ISE+K++T IE L Sbjct: 181 SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL 240 Query: 888 CRGYPSEFQSFFHYCRSLRFEDSPDYQYLKRLFRDLFIREGFQFDYVFDWTILKYQQSQM 1067 C+GYPSEF ++ ++CRSLRF+D PDY YL++LFR+LF R+GF +DYVFDW +LK+ S+ Sbjct: 241 CKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRA 300 Query: 1068 TSVPPRAIAAAAGQSSGMAPIASNNRLSATEEGRISGWSADPTRSQVPPTGINAGSLSKQ 1247 R + A+ L +T GR+ G T+ PPT + S + Sbjct: 301 ADDAERERRDREERLRHSRNPATRG-LPSTASGRLRG-----TQEVAPPTPLTPTSHTAN 354 Query: 1248 KSPVRPDLSAPKEAVLS 1298 SP RP +E +S Sbjct: 355 TSP-RPVSGMERERKVS 370
>P48730:KC1D_HUMAN Casein kinase I isoform delta - Homo sapiens (Human)| Length = 415 Score = 488 bits (1257), Expect = e-137 Identities = 239/377 (63%), Positives = 295/377 (78%) Frame = +3 Query: 168 MEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQ 347 ME RVGN+YRLGRK+GSGSFG+IYLGT++ EEVAIKLE VKTKHPQL ESK+Y+++Q Sbjct: 1 MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQ 60 Query: 348 GGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIH 527 GG GI ++W G EGDYNV+VM++LGPSLEDLF+FC+RK SLKTVL+LADQMI+R+E+IH Sbjct: 61 GGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIH 120 Query: 528 SKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYA 707 SK+F+HRD+KPDNFLMGLGK+ N VY+IDFGLAKKYRD THQHIPYRENKNLTGTARYA Sbjct: 121 SKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA 180 Query: 708 SVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKISERKIATSIEAL 887 S++THLGIEQSRRDD+ESLGYVLMYF GSLPWQGLKA TK+QKYE+ISE+K++T IE L Sbjct: 181 SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL 240 Query: 888 CRGYPSEFQSFFHYCRSLRFEDSPDYQYLKRLFRDLFIREGFQFDYVFDWTILKYQQSQM 1067 C+GYPSEF ++ ++CRSLRF+D PDY YL++LFR+LF R+GF +DYVFDW +LK+ S+ Sbjct: 241 CKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRA 300 Query: 1068 TSVPPRAIAAAAGQSSGMAPIASNNRLSATEEGRISGWSADPTRSQVPPTGINAGSLSKQ 1247 R + A+ L +T GR+ G T+ PPT + S + Sbjct: 301 ADDAERERRDREERLRHSRNPATRG-LPSTASGRLRG-----TQEVAPPTPLTPTSHTAN 354 Query: 1248 KSPVRPDLSAPKEAVLS 1298 SP RP +E +S Sbjct: 355 TSP-RPVSGMERERKVS 370
>P35508:KC1D_BOVIN Casein kinase I isoform delta - Bos taurus (Bovine)| Length = 415 Score = 488 bits (1257), Expect = e-137 Identities = 239/377 (63%), Positives = 295/377 (78%) Frame = +3 Query: 168 MEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQ 347 ME RVGN+YRLGRK+GSGSFG+IYLGT++ EEVAIKLE VKTKHPQL ESK+Y+++Q Sbjct: 1 MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQ 60 Query: 348 GGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIH 527 GG GI ++W G EGDYNV+VM++LGPSLEDLF+FC+RK SLKTVL+LADQMI+R+E+IH Sbjct: 61 GGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIH 120 Query: 528 SKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYA 707 SK+F+HRD+KPDNFLMGLGK+ N VY+IDFGLAKKYRD THQHIPYRENKNLTGTARYA Sbjct: 121 SKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA 180 Query: 708 SVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKISERKIATSIEAL 887 S++THLGIEQSRRDD+ESLGYVLMYF GSLPWQGLKA TK+QKYE+ISE+K++T IE L Sbjct: 181 SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL 240 Query: 888 CRGYPSEFQSFFHYCRSLRFEDSPDYQYLKRLFRDLFIREGFQFDYVFDWTILKYQQSQM 1067 C+GYPSEF ++ ++CRSLRF+D PDY YL++LFR+LF R+GF +DYVFDW +LK+ S+ Sbjct: 241 CKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRA 300 Query: 1068 TSVPPRAIAAAAGQSSGMAPIASNNRLSATEEGRISGWSADPTRSQVPPTGINAGSLSKQ 1247 R + A+ L +T GR+ G T+ PPT + S + Sbjct: 301 ADDAERERRDREERLRHSRNPATRG-LPSTASGRLRG-----TQEVAPPTPLTPTSHTAN 354 Query: 1248 KSPVRPDLSAPKEAVLS 1298 SP RP +E +S Sbjct: 355 TSP-RPVSGMERERKVS 370
>Q5ZLL1:KC1E_CHICK Casein kinase I isoform epsilon - Gallus gallus (Chicken)| Length = 416 Score = 487 bits (1253), Expect = e-137 Identities = 223/295 (75%), Positives = 266/295 (90%) Frame = +3 Query: 168 MEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQ 347 ME RVGNKYRLGRK+GSGSFG+IYLG N+ T EEVAIKLE VKTKHPQL ESK Y+++Q Sbjct: 1 MELRVGNKYRLGRKIGSGSFGDIYLGANIATGEEVAIKLECVKTKHPQLHIESKFYKMMQ 60 Query: 348 GGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIH 527 GG GI ++KW G EGDYNV+VM++LGPSLEDLF+FC+RK SLKTVL+LADQMI+R+E+IH Sbjct: 61 GGVGIPSIKWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIH 120 Query: 528 SKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYA 707 SK+F+HRD+KPDNFLMGLGK+ N VY+IDFGLAKKYRD THQHIPYRENKNLTGTARYA Sbjct: 121 SKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA 180 Query: 708 SVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKISERKIATSIEAL 887 S++THLGIEQSRRDD+ESLGYVLMYF GSLPWQGLKA TK+QKYE+ISE+K++T IE L Sbjct: 181 SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL 240 Query: 888 CRGYPSEFQSFFHYCRSLRFEDSPDYQYLKRLFRDLFIREGFQFDYVFDWTILKY 1052 C+GYPSEF ++ ++CRSLRF+D PDY YL++LFR+LF R+GF +DYVFDW +LK+ Sbjct: 241 CKGYPSEFSTYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKF 295
>P40235:HHP1_SCHPO Casein kinase I homolog hhp1 - Schizosaccharomyces pombe (Fission| yeast) Length = 365 Score = 477 bits (1227), Expect = e-134 Identities = 227/325 (69%), Positives = 269/325 (82%), Gaps = 9/325 (2%) Frame = +3 Query: 168 MEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQ 347 ++ R+GNKYR+GRK+GSGSFG+IYLGTNV + EEVAIKLE+ + KHPQL YE ++YR+L Sbjct: 3 LDLRIGNKYRIGRKIGSGSFGDIYLGTNVVSGEEVAIKLESTRAKHPQLEYEYRVYRILS 62 Query: 348 GGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIH 527 GG GI V+WFGVE DYN +VMD+LGPSLEDLF+FCNRK SLKTVL+LADQ+I+R+EFIH Sbjct: 63 GGVGIPFVRWFGVECDYNAMVMDLLGPSLEDLFNFCNRKFSLKTVLLLADQLISRIEFIH 122 Query: 528 SKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYA 707 SKSFLHRDIKPDNFLMG+GKR NQV +IDFGLAKKYRD TH HIPYRENKNLTGTARYA Sbjct: 123 SKSFLHRDIKPDNFLMGIGKRGNQVNIIDFGLAKKYRDHKTHLHIPYRENKNLTGTARYA 182 Query: 708 SVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKISERKIATSIEAL 887 S++THLGIEQSRRDD+ESLGYVL+YF RGSLPWQGLKA TKKQKYEKI E+KI+T E L Sbjct: 183 SINTHLGIEQSRRDDLESLGYVLVYFCRGSLPWQGLKATTKKQKYEKIMEKKISTPTEVL 242 Query: 888 CRGYPSEFQSFFHYCRSLRFEDSPDYQYLKRLFRDLFIREGFQFDYVFDWTILK------ 1049 CRG+P EF + +Y RSLRF+D PDY YL++LFRDLF R+ ++FDY+FDWT+ + Sbjct: 243 CRGFPQEFSIYLNYTRSLRFDDKPDYAYLRKLFRDLFCRQSYEFDYMFDWTLKRKTQQDQ 302 Query: 1050 ---YQQSQMTSVPPRAIAAAAGQSS 1115 Q Q S P+AI +SS Sbjct: 303 QHQQQLQQQLSATPQAINPPPERSS 327
>Q6QNM1:KC1_TOXGO Casein kinase I - Toxoplasma gondii| Length = 324 Score = 475 bits (1223), Expect = e-133 Identities = 217/299 (72%), Positives = 264/299 (88%) Frame = +3 Query: 168 MEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQ 347 ME RVG KYRLGRK+GSGSFG+IY+G N+ T +EVAIKLE++K+KHPQLLYESKLY++L Sbjct: 1 MEVRVGGKYRLGRKIGSGSFGDIYIGANILTGDEVAIKLESIKSKHPQLLYESKLYKLLA 60 Query: 348 GGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIH 527 GG GI V W+G+EGDYNV+V+D+LGPSLEDLFS CNRKLSLKTVLMLADQM+NR+EF+H Sbjct: 61 GGIGIPMVHWYGIEGDYNVMVIDLLGPSLEDLFSICNRKLSLKTVLMLADQMLNRIEFVH 120 Query: 528 SKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYA 707 SK+F+HRDIKPDNFL+G GK+ + VY+IDFGLAKKYRD T QHIPYRE KNLTGTARYA Sbjct: 121 SKNFIHRDIKPDNFLIGRGKKMSVVYIIDFGLAKKYRDPKTQQHIPYREGKNLTGTARYA 180 Query: 708 SVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKISERKIATSIEAL 887 S++THLGIEQSRRDD+E+LGYVLMYF RGSLPWQGLKA TKK KY+KI E+K++T IE L Sbjct: 181 SINTHLGIEQSRRDDLEALGYVLMYFNRGSLPWQGLKATTKKDKYDKIMEKKMSTPIEIL 240 Query: 888 CRGYPSEFQSFFHYCRSLRFEDSPDYQYLKRLFRDLFIREGFQFDYVFDWTILKYQQSQ 1064 C+ +P EF ++ +YCRSLRFED PDY YL+RLF+DLF REG+Q+D++FDWT + ++ + Sbjct: 241 CKHFPFEFITYLNYCRSLRFEDRPDYAYLRRLFKDLFFREGYQYDFIFDWTFINTEKDR 299
>Q6QNL9:KC1_EIMTE Casein kinase I - Eimeria tenella| Length = 335 Score = 468 bits (1203), Expect = e-131 Identities = 212/299 (70%), Positives = 262/299 (87%) Frame = +3 Query: 168 MEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQ 347 M+ RVG KYRLGRK+GSGSFG+IYLGTN+ T +EVAIKLE+V+++HPQL+YESKLY++L Sbjct: 1 MDVRVGGKYRLGRKIGSGSFGDIYLGTNISTGDEVAIKLESVRSRHPQLIYESKLYKILT 60 Query: 348 GGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIH 527 GG GI + W+G+EGDYNV+++++LGPSLEDLFS CNRKLSLKTVLMLADQM+NR+EF+H Sbjct: 61 GGIGIPTLYWYGIEGDYNVMIIELLGPSLEDLFSICNRKLSLKTVLMLADQMLNRIEFVH 120 Query: 528 SKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYA 707 S+ F+HRDIKPDNFL+G GK+ + V+ IDFGLAKKYRD T HIPYRE KNLTGTARYA Sbjct: 121 SRHFIHRDIKPDNFLIGRGKKMSIVFAIDFGLAKKYRDPRTQSHIPYREGKNLTGTARYA 180 Query: 708 SVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKISERKIATSIEAL 887 SV+THLGIEQSRRDD+E+LGYVLMYF RGSLPWQGLKA TKK KY+KI E+K++T IE L Sbjct: 181 SVNTHLGIEQSRRDDLEALGYVLMYFNRGSLPWQGLKATTKKDKYDKIMEKKMSTPIEVL 240 Query: 888 CRGYPSEFQSFFHYCRSLRFEDSPDYQYLKRLFRDLFIREGFQFDYVFDWTILKYQQSQ 1064 C+ +P EF ++ +YCRSLRFED PDY YL+RLF+DLF REG+Q+D++FDWT L ++ + Sbjct: 241 CKQFPFEFITYLNYCRSLRFEDRPDYSYLRRLFKDLFFREGYQYDFIFDWTFLHAERER 299
>P67963:KC1A_XENLA Casein kinase I isoform alpha - Xenopus laevis (African clawed frog)| Length = 337 Score = 452 bits (1163), Expect = e-126 Identities = 204/298 (68%), Positives = 257/298 (86%) Frame = +3 Query: 180 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTG 359 VG KY+L RK+GSGSFG+IYL N+ EEVA+KLE+ K +HPQLLYESKLY++LQGG G Sbjct: 13 VGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQGGVG 72 Query: 360 ISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSF 539 I +++W+G E DYNVLVMD+LGPSLEDLF+FC+R+ ++KTVLMLADQMI+R+E++H+K+F Sbjct: 73 IPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNF 132 Query: 540 LHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVST 719 +HRDIKPDNFLMG+G+ N++++IDFGLAKKYRD T QHIPYRE+KNLTGTARYAS++ Sbjct: 133 IHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASINA 192 Query: 720 HLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKISERKIATSIEALCRGY 899 HLGIEQSRRDDMESLGYVLMYF R SLPWQGLKA TKKQKYEKISE+K++T +E LC+G+ Sbjct: 193 HLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGF 252 Query: 900 PSEFQSFFHYCRSLRFEDSPDYQYLKRLFRDLFIREGFQFDYVFDWTILKYQQSQMTS 1073 P+EF + +YCR LRFE++PDY YL++LFR LF Q+DY FDWT+LK + +Q + Sbjct: 253 PAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQKAAQQAA 310
>P67829:KC1A_SHEEP Casein kinase I isoform alpha - Ovis aries (Sheep)| Length = 325 Score = 452 bits (1163), Expect = e-126 Identities = 204/298 (68%), Positives = 257/298 (86%) Frame = +3 Query: 180 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTG 359 VG KY+L RK+GSGSFG+IYL N+ EEVA+KLE+ K +HPQLLYESKLY++LQGG G Sbjct: 13 VGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQGGVG 72 Query: 360 ISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSF 539 I +++W+G E DYNVLVMD+LGPSLEDLF+FC+R+ ++KTVLMLADQMI+R+E++H+K+F Sbjct: 73 IPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNF 132 Query: 540 LHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVST 719 +HRDIKPDNFLMG+G+ N++++IDFGLAKKYRD T QHIPYRE+KNLTGTARYAS++ Sbjct: 133 IHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASINA 192 Query: 720 HLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKISERKIATSIEALCRGY 899 HLGIEQSRRDDMESLGYVLMYF R SLPWQGLKA TKKQKYEKISE+K++T +E LC+G+ Sbjct: 193 HLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGF 252 Query: 900 PSEFQSFFHYCRSLRFEDSPDYQYLKRLFRDLFIREGFQFDYVFDWTILKYQQSQMTS 1073 P+EF + +YCR LRFE++PDY YL++LFR LF Q+DY FDWT+LK + +Q + Sbjct: 253 PAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQKAAQQAA 310
>P67828:KC1A_RABIT Casein kinase I isoform alpha - Oryctolagus cuniculus (Rabbit)| Length = 325 Score = 452 bits (1163), Expect = e-126 Identities = 204/298 (68%), Positives = 257/298 (86%) Frame = +3 Query: 180 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTG 359 VG KY+L RK+GSGSFG+IYL N+ EEVA+KLE+ K +HPQLLYESKLY++LQGG G Sbjct: 13 VGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQGGVG 72 Query: 360 ISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSF 539 I +++W+G E DYNVLVMD+LGPSLEDLF+FC+R+ ++KTVLMLADQMI+R+E++H+K+F Sbjct: 73 IPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNF 132 Query: 540 LHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVST 719 +HRDIKPDNFLMG+G+ N++++IDFGLAKKYRD T QHIPYRE+KNLTGTARYAS++ Sbjct: 133 IHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASINA 192 Query: 720 HLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKISERKIATSIEALCRGY 899 HLGIEQSRRDDMESLGYVLMYF R SLPWQGLKA TKKQKYEKISE+K++T +E LC+G+ Sbjct: 193 HLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGF 252 Query: 900 PSEFQSFFHYCRSLRFEDSPDYQYLKRLFRDLFIREGFQFDYVFDWTILKYQQSQMTS 1073 P+EF + +YCR LRFE++PDY YL++LFR LF Q+DY FDWT+LK + +Q + Sbjct: 253 PAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQKAAQQAA 310
>Q8BK63:KC1A_MOUSE Casein kinase I isoform alpha - Mus musculus (Mouse)| Length = 337 Score = 452 bits (1163), Expect = e-126 Identities = 204/298 (68%), Positives = 257/298 (86%) Frame = +3 Query: 180 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTG 359 VG KY+L RK+GSGSFG+IYL N+ EEVA+KLE+ K +HPQLLYESKLY++LQGG G Sbjct: 13 VGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQGGVG 72 Query: 360 ISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSF 539 I +++W+G E DYNVLVMD+LGPSLEDLF+FC+R+ ++KTVLMLADQMI+R+E++H+K+F Sbjct: 73 IPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNF 132 Query: 540 LHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVST 719 +HRDIKPDNFLMG+G+ N++++IDFGLAKKYRD T QHIPYRE+KNLTGTARYAS++ Sbjct: 133 IHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASINA 192 Query: 720 HLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKISERKIATSIEALCRGY 899 HLGIEQSRRDDMESLGYVLMYF R SLPWQGLKA TKKQKYEKISE+K++T +E LC+G+ Sbjct: 193 HLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGF 252 Query: 900 PSEFQSFFHYCRSLRFEDSPDYQYLKRLFRDLFIREGFQFDYVFDWTILKYQQSQMTS 1073 P+EF + +YCR LRFE++PDY YL++LFR LF Q+DY FDWT+LK + +Q + Sbjct: 253 PAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQKAAQQAA 310
>P48729:KC1A_HUMAN Casein kinase I isoform alpha - Homo sapiens (Human)| Length = 337 Score = 452 bits (1163), Expect = e-126 Identities = 204/298 (68%), Positives = 257/298 (86%) Frame = +3 Query: 180 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTG 359 VG KY+L RK+GSGSFG+IYL N+ EEVA+KLE+ K +HPQLLYESKLY++LQGG G Sbjct: 13 VGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQGGVG 72 Query: 360 ISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSF 539 I +++W+G E DYNVLVMD+LGPSLEDLF+FC+R+ ++KTVLMLADQMI+R+E++H+K+F Sbjct: 73 IPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNF 132 Query: 540 LHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVST 719 +HRDIKPDNFLMG+G+ N++++IDFGLAKKYRD T QHIPYRE+KNLTGTARYAS++ Sbjct: 133 IHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASINA 192 Query: 720 HLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKISERKIATSIEALCRGY 899 HLGIEQSRRDDMESLGYVLMYF R SLPWQGLKA TKKQKYEKISE+K++T +E LC+G+ Sbjct: 193 HLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGF 252 Query: 900 PSEFQSFFHYCRSLRFEDSPDYQYLKRLFRDLFIREGFQFDYVFDWTILKYQQSQMTS 1073 P+EF + +YCR LRFE++PDY YL++LFR LF Q+DY FDWT+LK + +Q + Sbjct: 253 PAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQKAAQQAA 310
>P67962:KC1A_CHICK Casein kinase I isoform alpha - Gallus gallus (Chicken)| Length = 337 Score = 452 bits (1163), Expect = e-126 Identities = 204/298 (68%), Positives = 257/298 (86%) Frame = +3 Query: 180 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTG 359 VG KY+L RK+GSGSFG+IYL N+ EEVA+KLE+ K +HPQLLYESKLY++LQGG G Sbjct: 13 VGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQGGVG 72 Query: 360 ISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSF 539 I +++W+G E DYNVLVMD+LGPSLEDLF+FC+R+ ++KTVLMLADQMI+R+E++H+K+F Sbjct: 73 IPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNF 132 Query: 540 LHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVST 719 +HRDIKPDNFLMG+G+ N++++IDFGLAKKYRD T QHIPYRE+KNLTGTARYAS++ Sbjct: 133 IHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASINA 192 Query: 720 HLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKISERKIATSIEALCRGY 899 HLGIEQSRRDDMESLGYVLMYF R SLPWQGLKA TKKQKYEKISE+K++T +E LC+G+ Sbjct: 193 HLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGF 252 Query: 900 PSEFQSFFHYCRSLRFEDSPDYQYLKRLFRDLFIREGFQFDYVFDWTILKYQQSQMTS 1073 P+EF + +YCR LRFE++PDY YL++LFR LF Q+DY FDWT+LK + +Q + Sbjct: 253 PAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQKAAQQAA 310
>P67827:KC1A_BOVIN Casein kinase I isoform alpha - Bos taurus (Bovine)| Length = 325 Score = 452 bits (1163), Expect = e-126 Identities = 204/298 (68%), Positives = 257/298 (86%) Frame = +3 Query: 180 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTG 359 VG KY+L RK+GSGSFG+IYL N+ EEVA+KLE+ K +HPQLLYESKLY++LQGG G Sbjct: 13 VGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQGGVG 72 Query: 360 ISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSF 539 I +++W+G E DYNVLVMD+LGPSLEDLF+FC+R+ ++KTVLMLADQMI+R+E++H+K+F Sbjct: 73 IPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNF 132 Query: 540 LHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVST 719 +HRDIKPDNFLMG+G+ N++++IDFGLAKKYRD T QHIPYRE+KNLTGTARYAS++ Sbjct: 133 IHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASINA 192 Query: 720 HLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKISERKIATSIEALCRGY 899 HLGIEQSRRDDMESLGYVLMYF R SLPWQGLKA TKKQKYEKISE+K++T +E LC+G+ Sbjct: 193 HLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGF 252 Query: 900 PSEFQSFFHYCRSLRFEDSPDYQYLKRLFRDLFIREGFQFDYVFDWTILKYQQSQMTS 1073 P+EF + +YCR LRFE++PDY YL++LFR LF Q+DY FDWT+LK + +Q + Sbjct: 253 PAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQKAAQQAA 310
>O76324:DCO_DROME Discs overgrown protein kinase - Drosophila melanogaster (Fruit fly)| Length = 440 Score = 452 bits (1163), Expect = e-126 Identities = 212/319 (66%), Positives = 265/319 (83%) Frame = +3 Query: 168 MEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQ 347 ME RVGNKYRLGRK+GSGSFG+IYLGT + T EEVAIKLE ++TKHPQL ESK Y+ +Q Sbjct: 1 MELRVGNKYRLGRKIGSGSFGDIYLGTTINTGEEVAIKLECIRTKHPQLHIESKFYKTMQ 60 Query: 348 GGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIH 527 GG GI + W G EGDYNV+VM++LGPSLEDLF+FC+R+ SLKTVL+LADQMI+R+++IH Sbjct: 61 GGIGIPRIIWCGSEGDYNVMVMELLGPSLEDLFNFCSRRFSLKTVLLLADQMISRIDYIH 120 Query: 528 SKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYA 707 S+ F+HRDIKPDNFLMGLGK+ N VY+IDFGLAKK+RD + +HIPYRENKNLTGTARYA Sbjct: 121 SRDFIHRDIKPDNFLMGLGKKGNLVYIIDFGLAKKFRDARSLKHIPYRENKNLTGTARYA 180 Query: 708 SVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKISERKIATSIEAL 887 S++THLGIEQSRRDD+ESLGYVLMYF G+LPWQGLKA K+QKYE+ISE+K++TSI L Sbjct: 181 SINTHLGIEQSRRDDLESLGYVLMYFNLGALPWQGLKAANKRQKYERISEKKLSTSIVVL 240 Query: 888 CRGYPSEFQSFFHYCRSLRFEDSPDYQYLKRLFRDLFIREGFQFDYVFDWTILKYQQSQM 1067 C+G+PSEF ++ ++CR + F+ PDY +L++LFR+LF R GF +DYVFDW +LK+ + Sbjct: 241 CKGFPSEFVNYLNFCRQMHFDQRPDYCHLRKLFRNLFHRLGFTYDYVFDWNLLKFGGPR- 299 Query: 1068 TSVPPRAIAAAAGQSSGMA 1124 P+AI A + G A Sbjct: 300 ---NPQAIQQAQDGADGQA 315
>Q20471:KIN20_CAEEL Casein kinase I isoform delta - Caenorhabditis elegans| Length = 497 Score = 451 bits (1159), Expect = e-126 Identities = 222/340 (65%), Positives = 266/340 (78%), Gaps = 2/340 (0%) Frame = +3 Query: 54 AQTLATNLRNSSLA--QVPP*LDALNLGGGSVACVRARPPMEPRVGNKYRLGRKLGSGSF 227 A TL L + LA Q+PP L V + ME RVGN++RLGRK+GSGSF Sbjct: 152 ALTLDPTLLSHFLATQQIPPVPQPL---------VHKKAEMELRVGNRFRLGRKIGSGSF 202 Query: 228 GEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTGISNVKWFGVEGDYNVL 407 G+IYLG N+QTNEEVA+KLE VK+KHPQL ES+LYR++ GG GI ++W G EGDYNV+ Sbjct: 203 GDIYLGQNIQTNEEVAVKLECVKSKHPQLHIESRLYRIMLGGIGIPEIRWCGQEGDYNVM 262 Query: 408 VMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFLHRDIKPDNFLMGLGK 587 VM++LGPSLEDLF+FC RK SLKTVL+LADQM++RVEFIH + ++HRDIKPDNFLMGLGK Sbjct: 263 VMELLGPSLEDLFNFCQRKFSLKTVLLLADQMLSRVEFIHCRDYIHRDIKPDNFLMGLGK 322 Query: 588 RANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVSTHLGIEQSRRDDMESLG 767 R N VY+IDFGLAK+YRD S HQHI YRENKNLTGTARYAS++TH GIEQSRRDD+ESLG Sbjct: 323 RGNLVYIIDFGLAKRYRD-SKHQHIAYRENKNLTGTARYASINTHRGIEQSRRDDIESLG 381 Query: 768 YVLMYFLRGSLPWQGLKAGTKKQKYEKISERKIATSIEALCRGYPSEFQSFFHYCRSLRF 947 YV MYF RG+LPWQGLKA TK+QKYE ISE+KI+T ++ LC GYP F + +YCRSL F Sbjct: 382 YVFMYFNRGTLPWQGLKAVTKRQKYELISEKKISTRVDDLCAGYPEAFAQYLNYCRSLGF 441 Query: 948 EDSPDYQYLKRLFRDLFIREGFQFDYVFDWTILKYQQSQM 1067 E+ PDY YL+ LFR LF R+ F +DYVFDW K+ + Sbjct: 442 EEQPDYGYLRNLFRTLFHRQQFCYDYVFDWNTYKFYNESL 481
>P97633:KC1A_RAT Casein kinase I isoform alpha - Rattus norvegicus (Rat)| Length = 325 Score = 449 bits (1156), Expect = e-125 Identities = 203/298 (68%), Positives = 256/298 (85%) Frame = +3 Query: 180 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTG 359 VG KY+L RK+GSGSFG+IYL N+ EEVA+KLE+ K +HPQLLYESKLY++LQGG G Sbjct: 13 VGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQGGVG 72 Query: 360 ISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSF 539 I +++W+G DYNVLVMD+LGPSLEDLF+FC+R+ ++KTVLMLADQMI+R+E++H+K+F Sbjct: 73 IPHIRWYGQGKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNF 132 Query: 540 LHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVST 719 +HRDIKPDNFLMG+G+ N++++IDFGLAKKYRD T QHIPYRE+KNLTGTARYAS++ Sbjct: 133 IHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASINA 192 Query: 720 HLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKISERKIATSIEALCRGY 899 HLGIEQSRRDDMESLGYVLMYF R SLPWQGLKA TKKQKYEKISE+K++T +E LC+G+ Sbjct: 193 HLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGF 252 Query: 900 PSEFQSFFHYCRSLRFEDSPDYQYLKRLFRDLFIREGFQFDYVFDWTILKYQQSQMTS 1073 P+EF + +YCR LRFE++PDY YL++LFR LF Q+DY FDWT+LK + +Q + Sbjct: 253 PAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQKAAQQAA 310
>P42168:KC1A_CAEEL Casein kinase I isoform alpha - Caenorhabditis elegans| Length = 341 Score = 449 bits (1154), Expect = e-125 Identities = 212/324 (65%), Positives = 265/324 (81%), Gaps = 8/324 (2%) Frame = +3 Query: 180 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTG 359 V KY+L RK+GSGSFG+IY+ NV EEVAIKLE+ + +HPQLLYESK+YR+LQGG G Sbjct: 12 VATKYKLIRKIGSGSFGDIYVSINVTNGEEVAIKLESNRARHPQLLYESKVYRILQGGVG 71 Query: 360 ISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSF 539 I +++W+G E +YNVLVMD+LGPSLEDLF+FC+R+ ++KTVLMLADQMI R+E++H K+F Sbjct: 72 IPHIRWYGTEREYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMIGRIEYVHVKNF 131 Query: 540 LHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVST 719 +HRDIKPDNFLMG+G+ N++++IDFGLAKKYRD+ T HIPYRE+KNLTGTARYAS++ Sbjct: 132 IHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDSRTRTHIPYREDKNLTGTARYASINA 191 Query: 720 HLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKISERKIATSIEALCRGY 899 HLGIEQSRRDDMESLGYVLMYF RG+LPWQGLKA TKKQKYEKISE+K+ TS+E LC+G+ Sbjct: 192 HLGIEQSRRDDMESLGYVLMYFNRGTLPWQGLKAATKKQKYEKISEKKMTTSVEHLCKGF 251 Query: 900 PSEFQSFFHYCRSLRFEDSPDYQYLKRLFRDLFIREGFQFDYVFDWTILKY--QQSQMTS 1073 P+EF + Y R LRF++SPDY YL++LFR LF Q+DY FDWT+LK QQSQ + Sbjct: 252 PAEFPMYLSYTRGLRFDESPDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQKAQQSQSSG 311 Query: 1074 VP------PRAIAAAAGQSSGMAP 1127 VP A +AG +G+AP Sbjct: 312 VPGTNTTTQGATVPSAGVPAGVAP 335
>Q7RBX5:KC1_PLAYO Casein kinase I - Plasmodium yoelii yoelii| Length = 323 Score = 446 bits (1147), Expect = e-124 Identities = 201/291 (69%), Positives = 252/291 (86%) Frame = +3 Query: 168 MEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQ 347 ME RV NKY LG+KLGSGSFG+IY+ ++ T EE A+KLE+ ++KHPQLLYESKLY++L Sbjct: 1 MEIRVANKYALGKKLGSGSFGDIYVAKDIVTMEEFAVKLESTRSKHPQLLYESKLYKILG 60 Query: 348 GGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIH 527 GG G+ V W+G+EGD+ ++V+D+LGPSLEDLF+ CNRK SLKTVLM ADQM+NR+E++H Sbjct: 61 GGIGVPKVYWYGIEGDFTIMVLDLLGPSLEDLFTLCNRKFSLKTVLMTADQMLNRIEYVH 120 Query: 528 SKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYA 707 SK+F+HRDIKPDNFL+G GK+ +++IDFGLAKKYRD+ +H HIPY+E KNLTGTARYA Sbjct: 121 SKNFIHRDIKPDNFLIGRGKKVTLIHIIDFGLAKKYRDSRSHTHIPYKEGKNLTGTARYA 180 Query: 708 SVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKISERKIATSIEAL 887 S++THLGIEQSRRDD+E+LGYVLMYFLRGSLPWQGLKA +KK KY+KI E+KI+TS+E L Sbjct: 181 SINTHLGIEQSRRDDIEALGYVLMYFLRGSLPWQGLKAISKKDKYDKIMEKKISTSVEVL 240 Query: 888 CRGYPSEFQSFFHYCRSLRFEDSPDYQYLKRLFRDLFIREGFQFDYVFDWT 1040 CR EF ++ +YCRSLRFED PDY YL+RL +DLFIREGF +D++FDWT Sbjct: 241 CRNTSFEFVTYLNYCRSLRFEDRPDYTYLRRLLKDLFIREGFTYDFLFDWT 291
>Q8IHZ9:KC1_PLAF7 Casein kinase I - Plasmodium falciparum (isolate 3D7)| Length = 323 Score = 446 bits (1147), Expect = e-124 Identities = 201/291 (69%), Positives = 252/291 (86%) Frame = +3 Query: 168 MEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQ 347 ME RV NKY LG+KLGSGSFG+IY+ ++ T EE A+KLE+ ++KHPQLLYESKLY++L Sbjct: 1 MEIRVANKYALGKKLGSGSFGDIYVAKDIVTMEEFAVKLESTRSKHPQLLYESKLYKILG 60 Query: 348 GGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIH 527 GG G+ V W+G+EGD+ ++V+D+LGPSLEDLF+ CNRK SLKTVLM ADQM+NR+E++H Sbjct: 61 GGIGVPKVYWYGIEGDFTIMVLDLLGPSLEDLFTLCNRKFSLKTVLMTADQMLNRIEYVH 120 Query: 528 SKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYA 707 SK+F+HRDIKPDNFL+G GK+ +++IDFGLAKKYRD+ +H HIPY+E KNLTGTARYA Sbjct: 121 SKNFIHRDIKPDNFLIGRGKKVTLIHIIDFGLAKKYRDSRSHTHIPYKEGKNLTGTARYA 180 Query: 708 SVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKISERKIATSIEAL 887 S++THLGIEQSRRDD+E+LGYVLMYFLRGSLPWQGLKA +KK KY+KI E+KI+TS+E L Sbjct: 181 SINTHLGIEQSRRDDIEALGYVLMYFLRGSLPWQGLKAISKKDKYDKIMEKKISTSVEVL 240 Query: 888 CRGYPSEFQSFFHYCRSLRFEDSPDYQYLKRLFRDLFIREGFQFDYVFDWT 1040 CR EF ++ +YCRSLRFED PDY YL+RL +DLFIREGF +D++FDWT Sbjct: 241 CRNASFEFVTYLNYCRSLRFEDRPDYTYLRRLLKDLFIREGFTYDFLFDWT 291
>O15726:KC1_PLAF4 Casein kinase I - Plasmodium falciparum (isolate Dd2)| Length = 324 Score = 438 bits (1127), Expect = e-122 Identities = 198/291 (68%), Positives = 249/291 (85%) Frame = +3 Query: 168 MEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQ 347 ME RV NKY LG+KLGSGSFG+IY+ ++ T EE A+KLE+ ++KHPQLLYESKLY++L Sbjct: 1 MEIRVANKYALGKKLGSGSFGDIYVAKDIVTMEEFAVKLESTRSKHPQLLYESKLYKILG 60 Query: 348 GGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIH 527 GG G+ V W+G+EGD+ ++V+D+LGPSLEDLF+ CNRK SLKTV M ADQM+NR+E++H Sbjct: 61 GGIGVPKVYWYGIEGDFTIMVLDLLGPSLEDLFTLCNRKFSLKTVRMTADQMLNRIEYVH 120 Query: 528 SKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYA 707 SK+F+HRDIKPDNFL+G GK+ +++IDFGLAKKYRD+ +H PY+E KNLTGTARYA Sbjct: 121 SKNFIHRDIKPDNFLIGRGKKVTLIHIIDFGLAKKYRDSRSHTSYPYKEGKNLTGTARYA 180 Query: 708 SVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKISERKIATSIEAL 887 S++THLGIEQSRRDD+E+LGYVLMYFLRGSLPWQGLKA +KK KY+KI E+KI+TS+E L Sbjct: 181 SINTHLGIEQSRRDDIEALGYVLMYFLRGSLPWQGLKAISKKDKYDKIMEKKISTSVEVL 240 Query: 888 CRGYPSEFQSFFHYCRSLRFEDSPDYQYLKRLFRDLFIREGFQFDYVFDWT 1040 CR EF ++ +YCRSLRFED PDY YL+RL +DLFIREGF +D++FDWT Sbjct: 241 CRNASFEFVTYLNYCRSLRFEDRPDYTYLRRLLKDLFIREGFTYDFLFDWT 291
>Q8N752:KC1AL_HUMAN Casein kinase I isoform alpha-like - Homo sapiens (Human)| Length = 337 Score = 436 bits (1121), Expect = e-121 Identities = 207/330 (62%), Positives = 256/330 (77%) Frame = +3 Query: 180 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTG 359 VG KY+L RK+GSGSFG++YLG EEVA+KLE+ K KHPQLLYESKLY +LQGG G Sbjct: 13 VGGKYKLVRKIGSGSFGDVYLGITTTNGEEVAVKLESQKVKHPQLLYESKLYTILQGGVG 72 Query: 360 ISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSF 539 I ++ W+G E D NVLVMD+LGPSLEDLF+FC+R+ ++KTVLMLADQMI+R+E++H+K+F Sbjct: 73 IPHMHWYGQEKDNNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNF 132 Query: 540 LHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVST 719 LHRDIKPDNFLMG G+ N++++IDFGLAKKYRD T QHIPYRE+K+L GT RYAS++ Sbjct: 133 LHRDIKPDNFLMGTGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKHLIGTVRYASINA 192 Query: 720 HLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKISERKIATSIEALCRGY 899 HLGIEQSRRDDMESLGYV MYF R SLPWQGLKA TKKQKYEKISE+K++T +E LC+G+ Sbjct: 193 HLGIEQSRRDDMESLGYVFMYFNRTSLPWQGLKAMTKKQKYEKISEKKMSTPVEVLCKGF 252 Query: 900 PSEFQSFFHYCRSLRFEDSPDYQYLKRLFRDLFIREGFQFDYVFDWTILKYQQSQMTSVP 1079 P+EF + +YCR LRFE+ PDY YL++LFR LF Q+DY FDWT+LK + +Q Sbjct: 253 PAEFAMYLNYCRGLRFEEVPDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQKAAQQ---- 308 Query: 1080 PRAIAAAAGQSSGMAPIASNNRLSATEEGR 1169 A SSG A TE+ + Sbjct: 309 -------AASSSGQGQQAQTQTGKQTEKNK 331
>P40236:HHP2_SCHPO Casein kinase I homolog hhp2 - Schizosaccharomyces pombe (Fission| yeast) Length = 400 Score = 429 bits (1104), Expect = e-119 Identities = 200/327 (61%), Positives = 255/327 (77%), Gaps = 6/327 (1%) Frame = +3 Query: 177 RVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGT 356 ++GNKYR+GRK+GSGSFG+IYLG N E+VA+KLE +K +H QL YE ++Y +L+G Sbjct: 7 KIGNKYRIGRKIGSGSFGQIYLGLNTVNGEQVAVKLEPLKARHHQLEYEFRVYNILKGNI 66 Query: 357 GISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKS 536 GI ++WFGV YN +VMD+LGPSLEDLF +C RK +LKTVL+LADQ+I+R+E++HSKS Sbjct: 67 GIPTIRWFGVTNSYNAMVMDLLGPSLEDLFCYCGRKFTLKTVLLLADQLISRIEYVHSKS 126 Query: 537 FLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVS 716 FLHRDIKPDNFLM K +N V MIDFGLAKKYRD TH HIPYR+NKNLTGTARYAS++ Sbjct: 127 FLHRDIKPDNFLMK--KHSNVVTMIDFGLAKKYRDFKTHVHIPYRDNKNLTGTARYASIN 184 Query: 717 THLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKISERKIATSIEALCRG 896 TH+GIEQSRRDD+ESLGYVL+YF RGSLPWQGL+A TK+QKY++I + KI T +E LC+G Sbjct: 185 THIGIEQSRRDDLESLGYVLLYFCRGSLPWQGLQADTKEQKYQRIRDTKIGTPLEVLCKG 244 Query: 897 YPSEFQSFFHYCRSLRFEDSPDYQYLKRLFRDLFIREGFQFDYVFDWTILKYQQ------ 1058 P EF ++ Y R L F + P+Y YL++LFRDL IR+G+Q+DYVFDW ILKYQ+ Sbjct: 245 LPEEFITYMCYTRQLSFTEKPNYAYLRKLFRDLLIRKGYQYDYVFDWMILKYQKRAAAAA 304 Query: 1059 SQMTSVPPRAIAAAAGQSSGMAPIASN 1139 + + PP+ + Q+ + PI N Sbjct: 305 AASATAPPQVTSPMVSQTQPVNPITPN 331
>P29295:HRR25_YEAST Casein kinase I homolog HRR25 - Saccharomyces cerevisiae (Baker's| yeast) Length = 494 Score = 428 bits (1100), Expect = e-119 Identities = 197/331 (59%), Positives = 267/331 (80%) Frame = +3 Query: 168 MEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQ 347 M+ RVG K+R+GRK+GSGSFG+IY GTN+ + EEVAIKLE+++++HPQL YES++YR L Sbjct: 1 MDLRVGRKFRIGRKIGSGSFGDIYHGTNLISGEEVAIKLESIRSRHPQLDYESRVYRYLS 60 Query: 348 GGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIH 527 GG GI ++WFG EG+YN +V+D+LGPSLEDLF++C+R+ S KTV+MLA QM R+++IH Sbjct: 61 GGVGIPFIRWFGREGEYNAMVIDLLGPSLEDLFNYCHRRFSFKTVIMLALQMFCRIQYIH 120 Query: 528 SKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYA 707 +SF+HRDIKPDNFLMG+G+R + V++IDFGL+KKYRD +TH+HIPYRENK+LTGTARYA Sbjct: 121 GRSFIHRDIKPDNFLMGVGRRGSTVHVIDFGLSKKYRDFNTHRHIPYRENKSLTGTARYA 180 Query: 708 SVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKISERKIATSIEAL 887 SV+THLGIEQSRRDD+ESLGYVL+YF +GSLPWQGLKA TKKQKY++I E+K+ S+E L Sbjct: 181 SVNTHLGIEQSRRDDLESLGYVLIYFCKGSLPWQGLKATTKKQKYDRIMEKKLNVSVETL 240 Query: 888 CRGYPSEFQSFFHYCRSLRFEDSPDYQYLKRLFRDLFIREGFQFDYVFDWTILKYQQSQM 1067 C G P EFQ + YC++L+F++ PDY +L RLF+DL I+ + D++FDWT+L+Y ++ + Sbjct: 241 CSGLPLEFQEYMAYCKNLKFDEKPDYLFLARLFKDLSIKLEYHNDHLFDWTMLRYTKAMV 300 Query: 1068 TSVPPRAIAAAAGQSSGMAPIASNNRLSATE 1160 I ++ A ASN+ + +E Sbjct: 301 EKQRDLLIEKGDLNANSNAASASNSTDNKSE 331
>P54367:KC1A_DROME Casein kinase I isoform alpha - Drosophila melanogaster (Fruit fly)| Length = 337 Score = 421 bits (1082), Expect = e-117 Identities = 193/295 (65%), Positives = 243/295 (82%) Frame = +3 Query: 180 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTG 359 VG KYR+ RK+GSGSFG+IYLG ++Q+ EEVAIK+E+ +HPQLLYE+KLYR+L GG G Sbjct: 16 VGGKYRVIRKIGSGSFGDIYLGMSIQSGEEVAIKMESAHARHPQLLYEAKLYRILSGGVG 75 Query: 360 ISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSF 539 ++ G E ++N LVMD+LGPSLEDLF+FC R ++KTVLML DQMI R+E+IH K F Sbjct: 76 FPRIRHHGKEKNFNTLVMDLLGPSLEDLFNFCTRHFTIKTVLMLVDQMIGRLEYIHLKCF 135 Query: 540 LHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVST 719 +HRDIKPDNFLMG+G+ N++++IDFGLAKK+RD T HI YRE+KNLTGTARYAS++ Sbjct: 136 IHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKFRDPHTRHHIVYREDKNLTGTARYASINA 195 Query: 720 HLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKISERKIATSIEALCRGY 899 HLGIEQSRRDDMESLGYV+MYF RG LPWQG+KA TK+QKYEKISE+K++T IE LC+G Sbjct: 196 HLGIEQSRRDDMESLGYVMMYFNRGVLPWQGMKANTKQQKYEKISEKKMSTPIEVLCKGS 255 Query: 900 PSEFQSFFHYCRSLRFEDSPDYQYLKRLFRDLFIREGFQFDYVFDWTILKYQQSQ 1064 P+EF + +YCRSLRFE+ PDY YL++LFR LF Q+DY++DWT+LK + Q Sbjct: 256 PAEFSMYLNYCRSLRFEEQPDYMYLRQLFRILFRTLNHQYDYIYDWTMLKQKTHQ 310
>P35507:KC1B_BOVIN Casein kinase I isoform beta - Bos taurus (Bovine)| Length = 336 Score = 395 bits (1015), Expect = e-109 Identities = 181/306 (59%), Positives = 238/306 (77%) Frame = +3 Query: 156 ARPPMEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLY 335 +RP + VG +Y+L R++G GSFG +YL ++ +E+VA+KLE+ T+ P+LL+E +LY Sbjct: 5 SRPKTDVLVGGRYKLVREIGFGSFGHVYLAIDLTNHEQVAVKLESENTRQPRLLHEKELY 64 Query: 336 RVLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRV 515 LQGG GI ++W+G E DYNVLVMD+LGPSLEDLF+FC+R+ S+KTVLMLADQMI+R+ Sbjct: 65 NFLQGGVGIPQIRWYGQETDYNVLVMDLLGPSLEDLFNFCSRRFSMKTVLMLADQMISRI 124 Query: 516 EFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGT 695 E++HS++ +HRDIKPDNFLMG G + +++++DFGLAKKYRD T QHIP+R K+ GT Sbjct: 125 EYVHSRNLIHRDIKPDNFLMGTGPQWKKLFLVDFGLAKKYRDNRTGQHIPHRSGKSFIGT 184 Query: 696 ARYASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKISERKIATS 875 AS+S HLGIEQSRRDDMES+GYVLMYF RGSLPWQGLKA T KQK EKISE K+ T Sbjct: 185 PFCASISAHLGIEQSRRDDMESIGYVLMYFNRGSLPWQGLKAATLKQKCEKISEMKMTTP 244 Query: 876 IEALCRGYPSEFQSFFHYCRSLRFEDSPDYQYLKRLFRDLFIREGFQFDYVFDWTILKYQ 1055 ++ LC+G+P EF + YC L FE++PDY+YL++LFR LF + +Q DY FDW +LK + Sbjct: 245 VDVLCKGFPIEFAMYLKYCLRLSFEEAPDYRYLRQLFRLLFRKLSYQHDYAFDWIVLKQK 304 Query: 1056 QSQMTS 1073 Q S Sbjct: 305 AEQQAS 310
>P40233:CKI1_SCHPO Casein kinase I homolog 1 - Schizosaccharomyces pombe (Fission yeast)| Length = 446 Score = 353 bits (905), Expect = 2e-96 Identities = 195/419 (46%), Positives = 258/419 (61%), Gaps = 4/419 (0%) Frame = +3 Query: 180 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTG 359 VG Y++GR++G GSFG I+ GTN+ N++VAIK E ++ PQL E + Y++L G TG Sbjct: 8 VGVHYKVGRRIGEGSFGVIFEGTNLLNNQQVAIKFEPRRSDAPQLRDEYRTYKLLAGCTG 67 Query: 360 ISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSF 539 I NV +FG EG +N+LV+D+LGPSLEDL C RK S+KTV M A QM+ RV+ IH KS Sbjct: 68 IPNVYYFGQEGLHNILVIDLLGPSLEDLLDLCGRKFSVKTVAMAAKQMLARVQSIHEKSL 127 Query: 540 LHRDIKPDNFLMGL--GKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASV 713 ++RDIKPDNFL+G K AN +Y++DFG+ K YRD T QHIPYRE KNL+GTARY S+ Sbjct: 128 VYRDIKPDNFLIGRPNSKNANMIYVVDFGMVKFYRDPVTKQHIPYREKKNLSGTARYMSI 187 Query: 714 STHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKISERKIATSIEALCR 893 +THLG EQSRRDD+E+LG+V MYFLRGSLPWQGLKA T KQKYE+I E+K +T + LC Sbjct: 188 NTHLGREQSRRDDLEALGHVFMYFLRGSLPWQGLKAATNKQKYERIGEKKQSTPLRELCA 247 Query: 894 GYPSEFQSFFHYCRSLRFEDSPDYQYLKRLFRDLFIREGFQFDYVFDWTILKYQQSQMTS 1073 G+P EF + HY R+L F+ +PDY YL+ LF + R D FDW +L + S Sbjct: 248 GFPEEFYKYMHYARNLAFDATPDYDYLQGLFSKVLERLNTTEDENFDWNLLNNGKG-WQS 306 Query: 1074 VPPRAIAAAAGQSSGMAPIASNNRLSATEEGRISGWSADPTRS--QVPPTGINAGSLSKQ 1247 + R A Q S P S + S + RS + P + S S Sbjct: 307 LKSRN-AETENQRSSKPPAPKLESKSPALQNHASTQNVVSKRSDYEKPFAEPHLNSASDS 365 Query: 1248 KSPVRPDLSAPKEAVLSSSTFLGRSGVFSRRPAVSSSRDLPSSEAEPSRSRAPDVSPGT 1424 P + L P +++T RSG+ + +PA D SSE +R + + + T Sbjct: 366 AEPNQNSLPNPPTETKATTTVPDRSGLATNQPAPVDVHD--SSEERVTREQVQNATKET 422
>Q62763:KC1G3_RAT Casein kinase I isoform gamma-3 - Rattus norvegicus (Rat)| Length = 448 Score = 349 bits (896), Expect = 2e-95 Identities = 166/288 (57%), Positives = 222/288 (77%), Gaps = 2/288 (0%) Frame = +3 Query: 180 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTG 359 VG +R+G+K+G G+FGE+ LG N+ TNE VAIKLE +K++ PQL E + Y+ L G G Sbjct: 39 VGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSGDG 98 Query: 360 ISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSF 539 I V +FG G YN +V+++LGPSLEDLF C+R SLKTVLM+A Q+I+R+E++HSK+ Sbjct: 99 IPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNL 158 Query: 540 LHRDIKPDNFLMGL-GKRANQV-YMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASV 713 ++RD+KP+NFL+G G +A QV ++IDFGLAK+Y D T +HIPYRE+K+LTGTARY S+ Sbjct: 159 IYRDVKPENFLIGRPGNKAQQVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSI 218 Query: 714 STHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKISERKIATSIEALCR 893 +THLG EQSRRDD+E+LG++ MYFLRGSLPWQGLKA T K++Y+KI + K AT IE LC Sbjct: 219 NTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCE 278 Query: 894 GYPSEFQSFFHYCRSLRFEDSPDYQYLKRLFRDLFIREGFQFDYVFDW 1037 +P E ++ Y R L F + PDY YL++LF DLF R+G+ FDY +DW Sbjct: 279 NFPEEMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRKGYMFDYEYDW 326
>P40234:CKI2_SCHPO Casein kinase I homolog 2 - Schizosaccharomyces pombe (Fission yeast)| Length = 435 Score = 348 bits (892), Expect = 6e-95 Identities = 169/291 (58%), Positives = 216/291 (74%), Gaps = 2/291 (0%) Frame = +3 Query: 180 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTG 359 VG YR+GRK+G GSFG I+ G N+ N+ +AIK E K++ PQL E + Y++L G G Sbjct: 8 VGVHYRVGRKIGEGSFGVIFDGMNLLNNQLIAIKFEPKKSEAPQLRDEYRTYKLLVGNAG 67 Query: 360 ISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSF 539 I NV +FG EG +N+LV+D+LGPSLEDLF +C R+ S+KTV M A QM++RV+ IH K+ Sbjct: 68 IPNVYYFGQEGLHNILVIDLLGPSLEDLFEWCGRRFSVKTVAMTAKQMLSRVQTIHEKNL 127 Query: 540 LHRDIKPDNFLMGL--GKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASV 713 ++RDIKPDNFL+G + AN VYM+DFG+AK YRD T QHIPY E K+L+GTARY S+ Sbjct: 128 VYRDIKPDNFLIGRPSSRNANMVYMVDFGMAKYYRDPKTKQHIPYSERKSLSGTARYMSI 187 Query: 714 STHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKISERKIATSIEALCR 893 +THLG EQSRRDD+ESLG+V MYFLRGSLPWQGLKA K KYEKISE+K +TSI LC Sbjct: 188 NTHLGREQSRRDDLESLGHVFMYFLRGSLPWQGLKAANNKHKYEKISEKKQSTSISELCA 247 Query: 894 GYPSEFQSFFHYCRSLRFEDSPDYQYLKRLFRDLFIREGFQFDYVFDWTIL 1046 G+P+EF + Y RSL F++ PDY +L+ LF D+ G D V+DW +L Sbjct: 248 GFPNEFSKYMTYVRSLEFDEEPDYAFLQELFDDVLRANGDTNDGVYDWMLL 298
>P78368:KC1G2_HUMAN Casein kinase I isoform gamma-2 - Homo sapiens (Human)| Length = 415 Score = 346 bits (887), Expect = 2e-94 Identities = 162/288 (56%), Positives = 218/288 (75%), Gaps = 2/288 (0%) Frame = +3 Query: 180 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTG 359 VG +R+G+K+G G+FGE+ LG N+ TNE VAIKLE +K++ PQL E + Y+ L G Sbjct: 42 VGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLSATEG 101 Query: 360 ISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSF 539 + V +FG G YN +V+++LGPSLEDLF C+R +LKTVLM+A Q+I R+E++H+KS Sbjct: 102 VPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLITRMEYVHTKSL 161 Query: 540 LHRDIKPDNFLMGLG--KRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASV 713 ++RD+KP+NFL+G KR + +++IDFGLAK+Y D T +HIPYRE+K+LTGTARY S+ Sbjct: 162 IYRDVKPENFLVGRPGTKRQHAIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSI 221 Query: 714 STHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKISERKIATSIEALCR 893 +THLG EQSRRDD+E+LG++ MYFLRGSLPWQGLKA T K++Y+KI + K AT IE LC Sbjct: 222 NTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCE 281 Query: 894 GYPSEFQSFFHYCRSLRFEDSPDYQYLKRLFRDLFIREGFQFDYVFDW 1037 +P E ++ Y R L F + PDY YL++LF DLF R GF FDY +DW Sbjct: 282 NFPEEMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRSGFVFDYEYDW 329
>O74135:CKI3_SCHPO Casein kinase I homolog 3 - Schizosaccharomyces pombe (Fission yeast)| Length = 439 Score = 345 bits (886), Expect = 3e-94 Identities = 184/395 (46%), Positives = 251/395 (63%), Gaps = 27/395 (6%) Frame = +3 Query: 180 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTG 359 VG YR+G+K+G GSFG ++ G N+ N+ +A+K E+ K++ PQL E Y++L G G Sbjct: 11 VGVHYRVGKKIGEGSFGMLFQGVNLINNQPIALKFESRKSEVPQLRDEYLTYKLLMGLPG 70 Query: 360 ISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSF 539 I +V ++G EG YN+LVMD+LGPSLEDLF +C R+ S KTV M+A QMI R++ +H + F Sbjct: 71 IPSVYYYGQEGMYNLLVMDLLGPSLEDLFDYCGRRFSPKTVAMIAKQMITRIQSVHERHF 130 Query: 540 LHRDIKPDNFLMGL--GKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASV 713 ++RDIKPDNFL+G K N +Y +DFG+AK+YRD TH H PY E+K+L+GTARY S+ Sbjct: 131 IYRDIKPDNFLIGFPGSKTENVIYAVDFGMAKQYRDPKTHVHRPYNEHKSLSGTARYMSI 190 Query: 714 STHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKISERKIATSIEALCR 893 +THLG EQSRRDD+ES+G+V MYFLRGSLPWQGLKA T KQKYEKI E+K T ++ LC Sbjct: 191 NTHLGREQSRRDDLESMGHVFMYFLRGSLPWQGLKAATNKQKYEKIGEKKQVTPLKELCE 250 Query: 894 GYPSEFQSFFHYCRSLRFEDSPDYQYLKRLFRDLFIREGFQFDYVFDWTILK----YQQS 1061 GYP EF + Y R+L +E++PDY YL+ LF L +R D +DWT+L +Q S Sbjct: 251 GYPKEFLQYMIYARNLGYEEAPDYDYLRSLFDSLLLRINETDDGKYDWTLLNNGKGWQYS 310 Query: 1062 ------------------QMTSVPPRAIAAAAGQSSGMAPIASNNRLS---ATEEGRISG 1178 + +++PP A SS NN + AT++ I G Sbjct: 311 AAKQHVVQRRHTQGTNNRRQSTIPPYARTRQNLLSSPSKQTPVNNVVDASVATQKDGIPG 370 Query: 1179 WSADPTRSQVPPTGINAGSLSKQKSPVRPDLSAPK 1283 +A P Q T S ++Q+ P R + AP+ Sbjct: 371 KAASPQVQQQQQT-----SSAQQQQPQRVEQPAPQ 400
>Q62762:KC1G2_RAT Casein kinase I isoform gamma-2 - Rattus norvegicus (Rat)| Length = 415 Score = 345 bits (885), Expect = 4e-94 Identities = 161/288 (55%), Positives = 218/288 (75%), Gaps = 2/288 (0%) Frame = +3 Query: 180 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTG 359 VG +R+G+K+G G+FGE+ LG N+ TNE VAIKLE +K++ PQL E + Y+ L G Sbjct: 42 VGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLSTTEG 101 Query: 360 ISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSF 539 + V +FG G YN +V+++LGPSLEDLF C+R +LKTVLM+A Q+I R+E++H+KS Sbjct: 102 VPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLITRMEYVHTKSL 161 Query: 540 LHRDIKPDNFLMGL--GKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASV 713 ++RD+KP+NFL+G KR + +++IDFGLAK+Y D T +HIPYRE+K+LTGTARY S+ Sbjct: 162 IYRDVKPENFLVGRPGSKRQHSIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSI 221 Query: 714 STHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKISERKIATSIEALCR 893 +THLG EQSRRDD+E+LG++ MYFLRGSLPWQGLKA T K++Y+KI + K AT IE LC Sbjct: 222 NTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCE 281 Query: 894 GYPSEFQSFFHYCRSLRFEDSPDYQYLKRLFRDLFIREGFQFDYVFDW 1037 +P E ++ Y R L F + PDY YL++LF DLF R G+ FDY +DW Sbjct: 282 SFPEEMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRSGYVFDYEYDW 329
>Q8BVP5:KC1G2_MOUSE Casein kinase I isoform gamma-2 - Mus musculus (Mouse)| Length = 415 Score = 345 bits (885), Expect = 4e-94 Identities = 161/288 (55%), Positives = 218/288 (75%), Gaps = 2/288 (0%) Frame = +3 Query: 180 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTG 359 VG +R+G+K+G G+FGE+ LG N+ TNE VAIKLE +K++ PQL E + Y+ L G Sbjct: 42 VGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLSTTEG 101 Query: 360 ISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSF 539 + V +FG G YN +V+++LGPSLEDLF C+R +LKTVLM+A Q+I R+E++H+KS Sbjct: 102 VPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLITRMEYVHTKSL 161 Query: 540 LHRDIKPDNFLMGL--GKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASV 713 ++RD+KP+NFL+G KR + +++IDFGLAK+Y D T +HIPYRE+K+LTGTARY S+ Sbjct: 162 IYRDVKPENFLVGRPGSKRQHSIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSI 221 Query: 714 STHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKISERKIATSIEALCR 893 +THLG EQSRRDD+E+LG++ MYFLRGSLPWQGLKA T K++Y+KI + K AT IE LC Sbjct: 222 NTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCE 281 Query: 894 GYPSEFQSFFHYCRSLRFEDSPDYQYLKRLFRDLFIREGFQFDYVFDW 1037 +P E ++ Y R L F + PDY YL++LF DLF R G+ FDY +DW Sbjct: 282 SFPEEMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRSGYVFDYEYDW 329
>Q62761:KC1G1_RAT Casein kinase I isoform gamma-1 - Rattus norvegicus (Rat)| Length = 390 Score = 344 bits (882), Expect = 8e-94 Identities = 160/289 (55%), Positives = 222/289 (76%), Gaps = 3/289 (1%) Frame = +3 Query: 180 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVL-QGGT 356 VG +R+G+K+G G+FGE+ LG N+ TNE VAIKLE +K++ PQL E + Y+ L G Sbjct: 40 VGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLGSAGE 99 Query: 357 GISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKS 536 G+ V +FG G YN +V+++LGPSLEDLF C+R +LKTVLM+A Q+++R+E++HSK+ Sbjct: 100 GLPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLLSRMEYVHSKN 159 Query: 537 FLHRDIKPDNFLMGL--GKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYAS 710 ++RD+KP+NFL+G K+ + +++IDFGLAK+Y D T +HIPYRE+K+LTGTARY S Sbjct: 160 LIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMS 219 Query: 711 VSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKISERKIATSIEALC 890 ++THLG EQSRRDD+E+LG++ MYFLRGSLPWQGLKA T K++Y+KI + K +T IEALC Sbjct: 220 INTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRSTPIEALC 279 Query: 891 RGYPSEFQSFFHYCRSLRFEDSPDYQYLKRLFRDLFIREGFQFDYVFDW 1037 +P E ++ Y R L F + PDY+YL+ LF DLF R+G+ FDY +DW Sbjct: 280 ENFPEEMMTYLRYVRRLDFFEKPDYEYLRNLFTDLFERKGYTFDYAYDW 328
>Q9Y6M4:KC1G3_HUMAN Casein kinase I isoform gamma-3 - Homo sapiens (Human)| Length = 447 Score = 343 bits (880), Expect = 1e-93 Identities = 165/288 (57%), Positives = 221/288 (76%), Gaps = 2/288 (0%) Frame = +3 Query: 180 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTG 359 VG +R+G+K+G G+FGE+ LG N+ TNE VAIKLE +K++ PQL E + Y+ L G G Sbjct: 39 VGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSGDG 98 Query: 360 ISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSF 539 I V +FG G YN +V+++LGPSLEDLF C+R SLKTVLM+A Q+I+R+E++HSK+ Sbjct: 99 IPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNL 158 Query: 540 LHRDIKPDNFLMGL-GKRANQV-YMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASV 713 ++RD+KP+NFL+G G + QV ++IDFGLAK+Y D T +HIPYRE+K+LTGTARY S+ Sbjct: 159 IYRDVKPENFLIGRPGNKTQQVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSI 218 Query: 714 STHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKISERKIATSIEALCR 893 +THLG EQSRRDD+E+LG++ MYFLRGSLPWQGLKA T K++Y+KI + K AT IE LC Sbjct: 219 NTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCE 278 Query: 894 GYPSEFQSFFHYCRSLRFEDSPDYQYLKRLFRDLFIREGFQFDYVFDW 1037 +P E ++ Y R L F + PDY YL++LF DLF R+G+ FDY +DW Sbjct: 279 NFP-EMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRKGYMFDYEYDW 325
>Q8BTH8:KC1G1_MOUSE Casein kinase I isoform gamma-1 - Mus musculus (Mouse)| Length = 459 Score = 342 bits (877), Expect = 3e-93 Identities = 160/289 (55%), Positives = 221/289 (76%), Gaps = 3/289 (1%) Frame = +3 Query: 180 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVL-QGGT 356 VG +R+G+K+G G+FGE+ LG N+ TNE VAIKLE +K++ PQL E + Y+ L G Sbjct: 40 VGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLGSAGE 99 Query: 357 GISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKS 536 G+ V +FG G YN +V+++LGPSLEDLF C+R +LKTVLM+A Q+++R+E++HSK+ Sbjct: 100 GLPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLLSRMEYVHSKN 159 Query: 537 FLHRDIKPDNFLMGL--GKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYAS 710 ++RD+KP+NFL+G K+ + +++IDFGLAK+Y D T +HIPYRE+K+LTGTARY S Sbjct: 160 LIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEYVDPETKKHIPYREHKSLTGTARYMS 219 Query: 711 VSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKISERKIATSIEALC 890 ++THLG EQSRRDD+E+LG++ MYFLRGSLPWQGLKA T K++Y+KI + K T IEALC Sbjct: 220 INTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRNTPIEALC 279 Query: 891 RGYPSEFQSFFHYCRSLRFEDSPDYQYLKRLFRDLFIREGFQFDYVFDW 1037 +P E ++ Y R L F + PDY+YL+ LF DLF R+G+ FDY +DW Sbjct: 280 ENFPEEMATYLRYVRRLDFFEKPDYEYLRTLFTDLFERKGYTFDYAYDW 328
>Q9HCP0:KC1G1_HUMAN Casein kinase I isoform gamma-1 - Homo sapiens (Human)| Length = 422 Score = 341 bits (874), Expect = 7e-93 Identities = 159/289 (55%), Positives = 221/289 (76%), Gaps = 3/289 (1%) Frame = +3 Query: 180 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVL-QGGT 356 VG +R+G+K+G G+FGE+ LG N+ TNE VAIKLE +K++ PQL E + Y+ L G Sbjct: 40 VGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLGSAGE 99 Query: 357 GISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKS 536 G+ V +FG G YN +V+++LGPSLEDLF C+R +LKTVLM+A Q+++R+E++HSK+ Sbjct: 100 GLPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLLSRMEYVHSKN 159 Query: 537 FLHRDIKPDNFLMGL--GKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYAS 710 ++RD+KP+NFL+G K+ + +++IDFGLAK+Y D T +HIPYRE+K+LTGTARY S Sbjct: 160 LIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMS 219 Query: 711 VSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKISERKIATSIEALC 890 ++THLG EQSRRDD+E+LG++ MYFLRGSLPWQGLKA T K++Y+KI + K T IEALC Sbjct: 220 INTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRNTPIEALC 279 Query: 891 RGYPSEFQSFFHYCRSLRFEDSPDYQYLKRLFRDLFIREGFQFDYVFDW 1037 +P E ++ Y R L F + PDY+YL+ LF DLF ++G+ FDY +DW Sbjct: 280 ENFPEEMATYLRYVRRLDFFEKPDYEYLRTLFTDLFEKKGYTFDYAYDW 328
>P40230:RAG8_KLULA Casein kinase I homolog RAG8 - Kluyveromyces lactis (Yeast) (Candida| sphaerica) Length = 536 Score = 306 bits (783), Expect = 3e-82 Identities = 150/288 (52%), Positives = 201/288 (69%), Gaps = 2/288 (0%) Frame = +3 Query: 180 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTG 359 VG Y++G+K+G GSFG ++ G N+ N VAIK E KT PQL E + Y++L G G Sbjct: 73 VGLHYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSEG 132 Query: 360 ISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSF 539 I +FG EG +N+LV+D+LGPSLEDLF +C R+ S+KTV+ +A QMI +E +H Sbjct: 133 IPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHDL 192 Query: 540 LHRDIKPDNFLMGLGKR--ANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASV 713 ++RDIKPDNFL+G + AN V++IDFG+AK YRD T QHIPYRE K+L+GTARY S+ Sbjct: 193 IYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMSI 252 Query: 714 STHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKISERKIATSIEALCR 893 +THLG EQSRRDDME+LG+V YFLRG LPWQGLKA K KYEKI E+K +T++ L + Sbjct: 253 NTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVYDLSQ 312 Query: 894 GYPSEFQSFFHYCRSLRFEDSPDYQYLKRLFRDLFIREGFQFDYVFDW 1037 G P +F + R+L FE++PDY+ ++L + G + D +DW Sbjct: 313 GLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDW 360
>P23291:KC11_YEAST Casein kinase I homolog 1 - Saccharomyces cerevisiae (Baker's yeast)| Length = 538 Score = 306 bits (783), Expect = 3e-82 Identities = 152/288 (52%), Positives = 202/288 (70%), Gaps = 2/288 (0%) Frame = +3 Query: 180 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTG 359 VG Y++G+K+G GSFG ++ GTN+ VAIK E KT+ PQL E K Y++L G Sbjct: 65 VGLHYKIGKKIGEGSFGVLFEGTNMINGVPVAIKFEPRKTEAPQLRDEYKTYKILNGTPN 124 Query: 360 ISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSF 539 I +FG EG +N+LV+D+LGPSLEDLF +C RK S+KTV+ +A QMI +E +H+ Sbjct: 125 IPYAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRKFSVKTVVQVAVQMITLIEDLHAHDL 184 Query: 540 LHRDIKPDNFLMGLGKR--ANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASV 713 ++RDIKPDNFL+G + AN +++IDFG+AK+YRD T QHIPYRE K+L+GTARY S+ Sbjct: 185 IYRDIKPDNFLIGRPGQPDANNIHLIDFGMAKQYRDPKTKQHIPYREKKSLSGTARYMSI 244 Query: 714 STHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKISERKIATSIEALCR 893 +THLG EQSRRDDME+LG+V YFLRG LPWQGLKA KQKYEKI E+K +T++ L + Sbjct: 245 NTHLGREQSRRDDMEALGHVFFYFLRGHLPWQGLKAPNNKQKYEKIGEKKRSTNVYDLAQ 304 Query: 894 GYPSEFQSFFHYCRSLRFEDSPDYQYLKRLFRDLFIREGFQFDYVFDW 1037 G P +F + RSL FE+ PDY+ ++L + G D +DW Sbjct: 305 GLPVQFGRYLEIVRSLSFEECPDYEGYRKLLLSVLDDLGETADGQYDW 352
>P23292:KC12_YEAST Casein kinase I homolog 2 - Saccharomyces cerevisiae (Baker's yeast)| Length = 546 Score = 303 bits (776), Expect = 2e-81 Identities = 150/288 (52%), Positives = 203/288 (70%), Gaps = 2/288 (0%) Frame = +3 Query: 180 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTG 359 VG Y++G+K+G GSFG ++ GTN+ VAIK E KT+ PQL E + Y++L G G Sbjct: 72 VGLHYKIGKKIGEGSFGVLFEGTNMINGLPVAIKFEPRKTEAPQLKDEYRTYKILAGTPG 131 Query: 360 ISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSF 539 I +FG EG +N+LV+D+LGPSLEDLF +C R+ S+KTV+ +A QMI +E +H+ Sbjct: 132 IPQEYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSVKTVVQVAVQMITLIEDLHAHDL 191 Query: 540 LHRDIKPDNFLMGLGKR--ANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASV 713 ++RDIKPDNFL+G + AN+V++IDFG+AK+YRD T QHIPYRE K+L+GTARY S+ Sbjct: 192 IYRDIKPDNFLIGRPGQPDANKVHLIDFGMAKQYRDPKTKQHIPYREKKSLSGTARYMSI 251 Query: 714 STHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKISERKIATSIEALCR 893 +THLG EQSRRDDME++G+V YFLRG LPWQGLKA KQKYEKI E+K T++ L + Sbjct: 252 NTHLGREQSRRDDMEAMGHVFFYFLRGQLPWQGLKAPNNKQKYEKIGEKKRLTNVYDLAQ 311 Query: 894 GYPSEFQSFFHYCRSLRFEDSPDYQYLKRLFRDLFIREGFQFDYVFDW 1037 G P +F + R+L FE++PDY+ + L + G D +DW Sbjct: 312 GLPIQFGRYLEIVRNLSFEETPDYEGYRMLLLSVLDDLGETADGQYDW 359
>P35509:KC1G3_BOVIN Casein kinase I isoform gamma-3 - Bos taurus (Bovine)| Length = 276 Score = 297 bits (761), Expect = 9e-80 Identities = 145/252 (57%), Positives = 195/252 (77%), Gaps = 2/252 (0%) Frame = +3 Query: 180 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTG 359 VG +R+G+K+G G+FGE+ LG N+ TNE VAIKLE +K++ PQL E + Y+ L G G Sbjct: 25 VGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSGDG 84 Query: 360 ISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSF 539 I V +FG G YN +V+++LGPSLEDLF C+R SLKTVLM+A Q+I+R+E++HSK+ Sbjct: 85 IPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNL 144 Query: 540 LHRDIKPDNFLMGL-GKRANQV-YMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASV 713 ++RD+KP+NFL+G G + QV ++IDFGLAK+Y D T +HIPYRE+K+LTGTARY S+ Sbjct: 145 IYRDVKPENFLIGRPGNKTQQVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSI 204 Query: 714 STHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKISERKIATSIEALCR 893 +THLG EQSRRDD+E+LG++ MYFLRGSLPWQGLKA T K++Y+KI + K AT IE LC Sbjct: 205 NTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCE 264 Query: 894 GYPSEFQSFFHY 929 +P E ++ Y Sbjct: 265 NFP-EMATYLRY 275
>P39962:KC13_YEAST Casein kinase I homolog 3 - Saccharomyces cerevisiae (Baker's yeast)| Length = 524 Score = 283 bits (724), Expect = 2e-75 Identities = 152/323 (47%), Positives = 196/323 (60%), Gaps = 37/323 (11%) Frame = +3 Query: 180 VGNKYRLGRKLGSGSFGEIYLGTNV-----------------QTNEEVAIKLENVKTKHP 308 VG Y +G K+G GSFG I+ G N+ NE VAIK E + P Sbjct: 10 VGIHYAVGPKIGEGSFGVIFEGENILHSCQAQTGSKRDSSIIMANEPVAIKFEPRHSDAP 69 Query: 309 QLLYESKLYRVLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLM 488 QL E + YR+L G GI + +FG EG +N+L++D+LGPSLEDLF +C RK S+KT M Sbjct: 70 QLRDEFRAYRILNGCVGIPHAYYFGQEGMHNILIIDLLGPSLEDLFEWCGRKFSVKTTCM 129 Query: 489 LADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRA------------------NQVYMID 614 +A QMI+RV IH ++RDIKPDNFL+ +R N +YM+D Sbjct: 130 VAKQMIDRVRAIHDHDLIYRDIKPDNFLISQYQRISPEGKVIKSCASSSNNDPNLIYMVD 189 Query: 615 FGLAKKYRDTSTHQHIPYRENKNLTGTARYASVSTHLGIEQSRRDDMESLGYVLMYFLRG 794 FG+AK+YRD T QHIPYRE K+L+GTARY S++TH G EQSRRDD+ESLG+V YFLRG Sbjct: 190 FGMAKQYRDPRTKQHIPYRERKSLSGTARYMSINTHFGREQSRRDDLESLGHVFFYFLRG 249 Query: 795 SLPWQGLKAGTKKQKYEKI--SERKIATSIEALCRGYPSEFQSFFHYCRSLRFEDSPDYQ 968 SLPWQGLKA K KYEKI +++K+ L P +F ++ Y RSL+F++ PDY Sbjct: 250 SLPWQGLKAPNNKLKYEKIGMTKQKLNPDDLLLNNAIPYQFATYLKYARSLKFDEDPDYD 309 Query: 969 YLKRLFRDLFIREGFQFDYVFDW 1037 YL L D + D +DW Sbjct: 310 YLISLMDDALRLNDLKDDGHYDW 332
>O19175:KC1A_PIG Casein kinase I isoform alpha - Sus scrofa (Pig)| Length = 125 Score = 201 bits (511), Expect = 9e-51 Identities = 87/124 (70%), Positives = 115/124 (92%) Frame = +3 Query: 264 EEVAIKLENVKTKHPQLLYESKLYRVLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDL 443 EEVA+KLE+ K +HPQLLYESKLY++LQGG GI +++W+G E DYNVLVMD+LGPSLEDL Sbjct: 2 EEVAVKLESQKARHPQLLYESKLYKILQGGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDL 61 Query: 444 FSFCNRKLSLKTVLMLADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 623 F+FC+R+ ++KTVLMLADQMI+R+E++H+K+F+HRDIKPDNFLMG+G+ N++++IDFGL Sbjct: 62 FNFCSRRFTMKTVLMLADQMISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGL 121 Query: 624 AKKY 635 AKKY Sbjct: 122 AKKY 125
>Q6PCN3:TTBK1_MOUSE Tau-tubulin kinase 1 - Mus musculus (Mouse)| Length = 1308 Score = 172 bits (437), Expect = 3e-42 Identities = 151/467 (32%), Positives = 211/467 (45%), Gaps = 24/467 (5%) Frame = +3 Query: 129 GGGSVACVRARPPMEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHP 308 GGG A + P V +++++ +K+G G FGEIY ++ T E VA+K+E+ + Sbjct: 16 GGGEQADIL---PANYVVKDRWKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQQPKQ 72 Query: 309 QLLYESKLYRVLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNR-KLSLKTVL 485 L E + + LQG + G +N +VM + G +L DL R +L T L Sbjct: 73 VLKMEVAVLKKLQGKDHVCRFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFTLSTTL 132 Query: 486 MLADQMINRVEFIHSKSFLHRDIKPDNFLMG-LGKRANQVYMIDFGLAKKYRDTSTHQHI 662 L Q++ +E IHS FLHRDIKP NF MG L + YM+DFGLA++Y +T T Sbjct: 133 RLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYTNT-TGDVR 191 Query: 663 PYRENKNLTGTARYASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLK----AGTK 830 P R GT RYASV+ H E R DD+ SL Y+L+ F G LPW+ +K G Sbjct: 192 PPRNVAGFRGTVRYASVNAHKNREMGRHDDLWSLFYMLVEFAVGQLPWRKIKDKEQVGMI 251 Query: 831 KQKYEKISERKIATSIEALCRGYPSEFQSFFHYCRSLRFEDSPDYQYLKRLFRDLFIREG 1010 K+KYE L + PSEF F + SL + PDYQ + +F + G Sbjct: 252 KEKYEH----------RMLLKHMPSEFHLFLDHIASLDYFTKPDYQLIMSVFENSMKERG 301 Query: 1011 FQFDYVFDWTILKYQQ--SQMTSVPP----RAIAAAAGQSSGMAPIASNNRLSATE---- 1160 + FDW S TS PP R AA G + + P+ + TE Sbjct: 302 IAENEAFDWEKAGTDALLSTSTSTPPQQNTRQTAAMFGVVN-VTPVPGDLLRENTEDVLQ 360 Query: 1161 -EGRISGWSADPTRSQVPPTGINAGSLSKQKSPVRPDLSAPKEAVLSSSTFLGRSGV--- 1328 E +A P PP G+ G + P P EA + T + R+ + Sbjct: 361 GEHLSDQENAPPILPGRPPEGLGPG------PHLVPHPGGP-EAEVWEETDVNRNKLRIN 413 Query: 1329 FSRRPAVSSSRD----LPSSEAEPSRSRAPDVSPGTFQRNSAPRRAS 1457 + P V + +PSS RAP SP T R+ RR + Sbjct: 414 IGKTPCVEEEQSRGVGVPSSPV-----RAPPDSPTTPVRSLCYRRVN 455
>Q5TCY1:TTBK1_HUMAN Tau-tubulin kinase 1 - Homo sapiens (Human)| Length = 1321 Score = 171 bits (432), Expect = 1e-41 Identities = 117/327 (35%), Positives = 162/327 (49%), Gaps = 8/327 (2%) Frame = +3 Query: 129 GGGSVACVRARPPMEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHP 308 GGG A + P V +++++ +K+G G FGEIY ++ T E VA+K+E+ + Sbjct: 16 GGGEQADIL---PANYVVKDRWKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQQPKQ 72 Query: 309 QLLYESKLYRVLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNR-KLSLKTVL 485 L E + + LQG + G +N +VM + G +L DL R +L T L Sbjct: 73 VLKMEVAVLKKLQGKDHVCRFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFTLSTTL 132 Query: 486 MLADQMINRVEFIHSKSFLHRDIKPDNFLMG-LGKRANQVYMIDFGLAKKYRDTSTHQHI 662 L Q++ +E IHS FLHRDIKP NF MG L + YM+DFGLA++Y +T T Sbjct: 133 RLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYTNT-TGDVR 191 Query: 663 PYRENKNLTGTARYASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLK----AGTK 830 P R GT RYASV+ H E R DD+ SL Y+L+ F G LPW+ +K G Sbjct: 192 PPRNVAGFRGTVRYASVNAHKNREMGRHDDLWSLFYMLVEFAVGQLPWRKIKDKEQVGMI 251 Query: 831 KQKYEKISERKIATSIEALCRGYPSEFQSFFHYCRSLRFEDSPDYQYLKRLFRDLFIREG 1010 K+KYE L + PSEF F + SL + PDYQ + +F + G Sbjct: 252 KEKYEH----------RMLLKHMPSEFHLFLDHIASLDYFTKPDYQLIMSVFENSMKERG 301 Query: 1011 FQFDYVFDWTILKYQQ--SQMTSVPPR 1085 + FDW S TS PP+ Sbjct: 302 IAENEAFDWEKAGTDALLSTSTSTPPQ 328
>Q3UVR3:TTBK2_MOUSE Tau-tubulin kinase 2 - Mus musculus (Mouse)| Length = 1243 Score = 155 bits (391), Expect = 7e-37 Identities = 100/288 (34%), Positives = 148/288 (51%), Gaps = 2/288 (0%) Frame = +3 Query: 180 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTG 359 V ++++ RK+G G FGEIY ++ T E VA+K+E+ + L E + + LQG Sbjct: 17 VKERWKVLRKIGGGGFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDH 76 Query: 360 ISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNR-KLSLKTVLMLADQMINRVEFIHSKS 536 + G +N +VM + G +L DL +R ++ T L L Q++ +E IHS Sbjct: 77 VCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGKQILESIESIHSVG 136 Query: 537 FLHRDIKPDNFLMG-LGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASV 713 FLHRDIKP NF MG + +M+DFGLA+++ + S P R GT RYAS+ Sbjct: 137 FLHRDIKPSNFAMGRFPSTCRKCFMLDFGLARQFTN-SCGDVRPPRAVAGFRGTVRYASI 195 Query: 714 STHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKISERKIATSIEALCR 893 + H E R DD+ SL Y+L+ F+ G LPW+ +K K++ I ER + + Sbjct: 196 NAHRNREMGRHDDLWSLFYMLVEFVVGQLPWRKIK---DKEQVGSIKER---YDHRLMLK 249 Query: 894 GYPSEFQSFFHYCRSLRFEDSPDYQYLKRLFRDLFIREGFQFDYVFDW 1037 P EF +F + SL + PDYQ L +F + G FDW Sbjct: 250 HLPPEFSTFLDHISSLDYFTKPDYQLLTSVFDNSIKTFGVIESDPFDW 297
>Q6IQ55:TTBK2_HUMAN Tau-tubulin kinase 2 - Homo sapiens (Human)| Length = 1244 Score = 155 bits (391), Expect = 7e-37 Identities = 101/288 (35%), Positives = 147/288 (51%), Gaps = 2/288 (0%) Frame = +3 Query: 180 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTG 359 V ++++ RK+G G FGEIY ++ T E VA+K+E+ + L E + + LQG Sbjct: 17 VKERWKVLRKIGGGGFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDH 76 Query: 360 ISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNR-KLSLKTVLMLADQMINRVEFIHSKS 536 + G +N +VM + G +L DL +R ++ T L L Q++ +E IHS Sbjct: 77 VCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVG 136 Query: 537 FLHRDIKPDNFLMG-LGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASV 713 FLHRDIKP NF MG + YM+DFGLA+++ + S P R GT RYAS+ Sbjct: 137 FLHRDIKPSNFAMGRFPSTCRKCYMLDFGLARQFTN-SCGDVRPPRAVAGFRGTVRYASI 195 Query: 714 STHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKISERKIATSIEALCR 893 + H E R DD+ SL Y+L+ F+ G LPW+ +K K++ I ER + + Sbjct: 196 NAHRNREMGRHDDLWSLFYMLVEFVVGQLPWRKIK---DKEQVGSIKER---YDHRLMLK 249 Query: 894 GYPSEFQSFFHYCRSLRFEDSPDYQYLKRLFRDLFIREGFQFDYVFDW 1037 P EF F + SL + PDYQ L +F + G FDW Sbjct: 250 HLPPEFSIFLDHISSLDYFTKPDYQLLTSVFDNSIKTFGVIESDPFDW 297
>P81123:KC1D_RABIT Casein kinase I isoform delta - Oryctolagus cuniculus (Rabbit)| Length = 81 Score = 145 bits (367), Expect = 4e-34 Identities = 68/78 (87%), Positives = 73/78 (93%) Frame = +3 Query: 552 IKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVSTHLGI 731 I PDNFLMGLGK+ N VY+IDFGLAKKYRD THQHIPYRENKNLTGTARYAS++THLGI Sbjct: 2 IFPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGI 61 Query: 732 EQSRRDDMESLGYVLMYF 785 EQSRRDD+ESLGYVLMYF Sbjct: 62 EQSRRDDLESLGYVLMYF 79
>Q86Y07:VRK2_HUMAN Serine/threonine-protein kinase VRK2 - Homo sapiens (Human)| Length = 508 Score = 121 bits (303), Expect = 1e-26 Identities = 93/298 (31%), Positives = 140/298 (46%), Gaps = 31/298 (10%) Frame = +3 Query: 183 GNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVK-TKHPQLLYESKLYR------- 338 GN++ LG+K+GSG FG IYL E+ A + V+ ++ L E K Y+ Sbjct: 26 GNQWVLGKKIGSGGFGLIYLAFPTNKPEKDARHVVKVEYQENGPLFSELKFYQRVAKKDC 85 Query: 339 ---------------VLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSL 473 L G+G++ K Y +VM+ LG L+ + S N Sbjct: 86 IKKWIERKQLDYLGIPLFYGSGLTEFKG----RSYRFMVMERLGIDLQKI-SGQNGTFKK 140 Query: 474 KTVLMLADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTH 653 TVL L +M++ +E+IH ++H DIK N L+G K +QVY+ D+GL+ +Y H Sbjct: 141 STVLQLGIRMLDVLEYIHENEYVHGDIKAANLLLGY-KNPDQVYLADYGLSYRYCPNGNH 199 Query: 654 QHIPYRENKNLTGTARYASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPW-QGLK--AG 824 + K GT + S+ H G+ SRR D+E LGY ++ +L G LPW Q LK Sbjct: 200 KQYQENPRKGHNGTIEFTSLDAHKGVALSRRSDVEILGYCMLRWLCGKLPWEQNLKDPVA 259 Query: 825 TKKQKYEKISE-----RKIATSIEALCRGYPSEFQSFFHYCRSLRFEDSPDYQYLKRL 983 + K + E K A S + C E F SL +++ P+YQ LK++ Sbjct: 260 VQTAKTNLLDELPQSVLKWAPSGSSCC-----EIAQFLVCAHSLAYDEKPNYQALKKI 312
>Q32PI1:VRK1_BOVIN Serine/threonine-protein kinase VRK1 - Bos taurus (Bovine)| Length = 396 Score = 121 bits (303), Expect = 1e-26 Identities = 84/313 (26%), Positives = 145/313 (46%), Gaps = 26/313 (8%) Frame = +3 Query: 189 KYRLGRKLGSGSFGEIYLGT-----NVQTNEEVAIKLENVKTKHPQLLYESKLYR----- 338 +++LG +G G FG IYL +V + +K+E + + L E K Y+ Sbjct: 36 EWKLGSPIGQGGFGCIYLADMNSSKSVGNDAPCVVKVE--PSDNGPLFTELKFYQRAAKP 93 Query: 339 -VLQGGTGISNVKWFGVEG------------DYNVLVMDVLGPSLEDLFSFCNRKLSLKT 479 +Q +K+ GV Y +++D G L+ ++ ++ S KT Sbjct: 94 EQIQKWIRTHKLKYLGVPKYWGSGLHDKNGKSYRFMIIDRFGSDLQKIYEANAKRFSRKT 153 Query: 480 VLMLADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQH 659 VL L+ ++++ +E+IH ++H DIK N L+ K +QVY++D+GLA +Y TH+ Sbjct: 154 VLQLSLRILDILEYIHEHEYVHGDIKASNLLLSY-KNPDQVYLVDYGLAYRYCPEGTHKE 212 Query: 660 IPYRENKNLTGTARYASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQK 839 + GT + S+ H G+ SRR D+E LGY ++ +L G LPW+ + Sbjct: 213 YKEDPKRCHDGTVEFTSIDAHNGVAPSRRGDLEILGYCMIQWLSGHLPWEDNLKDPNYVR 272 Query: 840 YEKISERKIATSIEALC---RGYPSEFQSFFHYCRSLRFEDSPDYQYLKRLFRDLFIREG 1010 KI R+ S+ C + P E + + L + + P YQ L+ + G Sbjct: 273 DSKIRYRENIASLMDKCFPEKNKPDEIAKYMETVKLLDYVEKPLYQKLRDILLQGLKAIG 332 Query: 1011 FQFDYVFDWTILK 1049 + D D T+++ Sbjct: 333 SKDDGKLDLTVVE 345
>Q9J523:V212_FOWPV Probable serine/threonine-protein kinase FPV212 - Fowlpox virus| (FPV) Length = 303 Score = 121 bits (303), Expect = 1e-26 Identities = 86/298 (28%), Positives = 141/298 (47%), Gaps = 25/298 (8%) Frame = +3 Query: 168 MEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLY-RVL 344 +E NK+ LG++LGSG FG +Y + + K+E ++ L E Y RV+ Sbjct: 17 LEDITKNKWILGKQLGSGGFGLVYQVSCKSKEIDCVAKIELKESGG--LFCEINFYNRVM 74 Query: 345 QGGT--------------GISNVKWFGV----EGDYNVLVMDVLGPSLEDLFSFCNRKLS 470 + T GI + FG+ +Y ++ LG LE++ S K + Sbjct: 75 KNKTSLDTWMKEQKIDYIGIPSFHGFGITIYKNVEYRFAIIQRLGRDLENILSE-KEKFN 133 Query: 471 LKTVLMLADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTST 650 + + LA ++++ ++FIHSK F H DIK N L G K ++VY++D+GLA KY Sbjct: 134 ITVIKKLAIKILDILKFIHSKEFSHGDIKAGNILFG--KDDDKVYLVDYGLATKYSSNGK 191 Query: 651 HQHIPYRENKNLTGTARYASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLK---- 818 H+ GT + S+ H G+ SRR D+ESLG+ ++ + G LPW+ + Sbjct: 192 HKEYTINPKNRHNGTMAFTSIDAHKGVTVSRRGDLESLGFCMLKWYSGKLPWEKYEKEPE 251 Query: 819 --AGTKKQKYEKISERKIATSIEALCRGYPSEFQSFFHYCRSLRFEDSPDYQYLKRLF 986 G K+ IS++ I + Y L +E++P+Y+ LK++F Sbjct: 252 NVQGMKEAFVNNISKKTIPFKNAGIIYNY-------IKVVTKLEYEEAPNYESLKQMF 302
>Q99986:VRK1_HUMAN Serine/threonine-protein kinase VRK1 - Homo sapiens (Human)| Length = 396 Score = 119 bits (298), Expect = 4e-26 Identities = 80/288 (27%), Positives = 135/288 (46%), Gaps = 25/288 (8%) Frame = +3 Query: 189 KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQ----LLYESKLYR------ 338 ++++G +G G FG IYL ++ ++E V V P L E K Y+ Sbjct: 36 EWKVGLPIGQGGFGCIYLA-DMNSSESVGSDAPCVVKVEPSDNGPLFTELKFYQRAAKPE 94 Query: 339 VLQGGTGISNVKWFGVEG------------DYNVLVMDVLGPSLEDLFSFCNRKLSLKTV 482 +Q +K+ GV Y ++MD G L+ ++ ++ S KTV Sbjct: 95 QIQKWIRTRKLKYLGVPKYWGSGLHDKNGKSYRFMIMDRFGSDLQKIYEANAKRFSRKTV 154 Query: 483 LMLADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHI 662 L L+ ++++ +E+IH ++H DIK N L+ K +QVY++D+GLA +Y H+ Sbjct: 155 LQLSLRILDILEYIHEHEYVHGDIKASNLLLNY-KNPDQVYLVDYGLAYRYCPEGVHKEY 213 Query: 663 PYRENKNLTGTARYASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKY 842 + GT + S+ H G+ SRR D+E LGY ++ +L G LPW+ K + Sbjct: 214 KEDPKRCHDGTIEFTSIDAHNGVAPSRRGDLEILGYCMIQWLTGHLPWEDNLKDPKYVRD 273 Query: 843 EKISERKIATSIEALC---RGYPSEFQSFFHYCRSLRFEDSPDYQYLK 977 KI R+ S+ C + P E + + L + + P Y+ L+ Sbjct: 274 SKIRYRENIASLMDKCFPEKNKPGEIAKYMETVKLLDYTEKPLYENLR 321
>Q80X41:VRK1_MOUSE Serine/threonine-protein kinase VRK1 - Mus musculus (Mouse)| Length = 440 Score = 119 bits (297), Expect = 6e-26 Identities = 81/289 (28%), Positives = 136/289 (47%), Gaps = 26/289 (8%) Frame = +3 Query: 189 KYRLGRKLGSGSFGEIYLG-TN----VQTNEEVAIKLENVKTKHPQLLYESKLYR----- 338 +++LG +G G FG IYL TN V ++ +K+E + + L E K Y+ Sbjct: 36 EWKLGLPIGQGGFGCIYLADTNSSKPVGSDAPCVVKVE--PSDNGPLFTELKFYQRAAKP 93 Query: 339 -VLQGGTGISNVKWFGVEG------------DYNVLVMDVLGPSLEDLFSFCNRKLSLKT 479 +Q +K+ GV Y ++MD G L+ ++ ++ S KT Sbjct: 94 EQIQKWIRTHKLKYLGVPKYWGSGLHDKNGKSYRFMIMDRFGSDLQKIYEANAKRFSRKT 153 Query: 480 VLMLADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQH 659 VL L+ ++++ +E+IH ++H DIK N L+ K +QVY++D+GLA +Y H+ Sbjct: 154 VLQLSLRILDILEYIHEHEYVHGDIKASNLLLS-HKNPDQVYLVDYGLAYRYCPDGVHKE 212 Query: 660 IPYRENKNLTGTARYASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQK 839 + GT + S+ H G+ SRR D+E LGY ++ +L G LPW+ + Sbjct: 213 YKEDPKRCHDGTLEFTSIDAHKGVAPSRRGDLEILGYCMIQWLSGCLPWEDNLKDPNYVR 272 Query: 840 YEKISERKIATSIEALC---RGYPSEFQSFFHYCRSLRFEDSPDYQYLK 977 KI R ++ C + P E + + L + + P YQ L+ Sbjct: 273 DSKIRYRDNVAALMEKCFPEKNKPGEIAKYMESVKLLEYTEKPLYQNLR 321
>Q7ZUS1:VRK1_DANRE Serine/threonine-protein kinase VRK1 - Danio rerio (Zebrafish)| (Brachydanio rerio) Length = 425 Score = 117 bits (294), Expect = 1e-25 Identities = 102/427 (23%), Positives = 176/427 (41%), Gaps = 29/427 (6%) Frame = +3 Query: 189 KYRLGRKLGSGSFGEIYLGTN-----VQTNEEVAIKLENVKTKHPQLLYESKLYR----- 338 K++LG +G G FG +YL V + IK+E + + L E K Y Sbjct: 37 KWKLGSAVGQGGFGLLYLANEDSSGPVTADAPYVIKVE--PSDNGPLFSELKFYMRAAKP 94 Query: 339 -VLQGGTGISNVKWFGVEG------------DYNVLVMDVLGPSLEDLFSFCNRKLSLKT 479 ++ +++ GV Y +VMD G L+ LF +K S K Sbjct: 95 DLIGAWMKSKKMEYLGVPKYWGSGFHEKNGKRYRFMVMDRFGTDLQKLFEGNGKKFSRKL 154 Query: 480 VLMLADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQH 659 VL L ++++ +E+IH ++H DIK N L+ NQV+++D+GLA +Y + Sbjct: 155 VLQLGLRLLDILEYIHDHEYVHADIKASNLLLSY-TNPNQVFLVDYGLAYRYAPEGVPKE 213 Query: 660 IPYRENKNLTGTARYASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQK 839 + GT + S+ H G+ SRR D+E +GY ++ +L LPW+ + Sbjct: 214 YKEDPKRCHDGTIEFTSIDAHKGVSPSRRADLEIMGYCMIQWLCSRLPWED---KLQDPL 270 Query: 840 YEKISERKIATSIEALCR------GYPSEFQSFFHYCRSLRFEDSPDYQYLKRLFRDLFI 1001 Y + S+ + +I+ + P+E F + L + D PDY L+ + + Sbjct: 271 YVRDSKLRCRDNIDEFLKSCFASGNIPAEMGKFMQEVKVLGYTDRPDYDKLRGILQQGLK 330 Query: 1002 REGFQFDYVFDWTILKYQQSQMTSVPPRAIAAAAGQSSGMAPIASNNRLSATEEGRISGW 1181 G D D+ + A S+ + + + R A E+G+ Sbjct: 331 SIGSTDDKKLDFGV-------------------ATNSTSLPSVKTPKRKKAEEKGQ---- 367 Query: 1182 SADPTRSQVPPTGINAGSLSKQKSPVRPDLSAPKEAVLSSSTFLGRSGVFSRRPAVSSSR 1361 SAD T S K+++P + +++ K+ + + + S PAV SR Sbjct: 368 SADETDST---------PAKKRRAPQKKEVNGAKKTASPAKRPVKKETQASSEPAVKKSR 418 Query: 1362 DLPSSEA 1382 P + Sbjct: 419 GRPKKNS 425
>Q8BN21:VRK2_MOUSE Serine/threonine-protein kinase VRK2 - Mus musculus (Mouse)| Length = 503 Score = 117 bits (292), Expect = 2e-25 Identities = 89/293 (30%), Positives = 134/293 (45%), Gaps = 26/293 (8%) Frame = +3 Query: 183 GNKYRLGRKLGSGSFGEIYLG--TNVQTNE-EVAIKLENVKTKHPQLLYESKLYRVLQGG 353 GN++ LG+ +GSG FG IYL TN + IKLE ++ L E K Y+ Sbjct: 26 GNRWALGKMIGSGGFGLIYLAFPTNKPNKDARHVIKLEY--QENGPLFSELKFYQRAAKR 83 Query: 354 TGISNVKW----------------FGVEG----DYNVLVMDVLGPSLEDLFSFCNRKLSL 473 I KW FG+ Y +VM+ LG L+ L N Sbjct: 84 ECIQ--KWIQQRKLDYLGIPVFYGFGLTDFKGRSYRFMVMERLGIDLQKLLDQ-NGGFKK 140 Query: 474 KTVLMLADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTH 653 TVL L +M++ +E+IH ++H DIK N L+ ++VY+ D+GL+ +Y H Sbjct: 141 LTVLQLGIRMLDVLEYIHENEYVHGDIKAANLLLDF-TNPDRVYLADYGLSYRYCPNGNH 199 Query: 654 QHIPYRENKNLTGTARYASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGL---KAG 824 + K GT + S+ H G+ SRR D+E LGY ++++L G LPW+ Sbjct: 200 KQYQEDPRKGHNGTIEFTSLDAHKGVAPSRRSDVEILGYCMLHWLFGKLPWEAKLDDPVA 259 Query: 825 TKKQKYEKISERKIATSIEALCRGYPSEFQSFFHYCRSLRFEDSPDYQYLKRL 983 + K + E + A SE + Y +L ++D PDYQ LK++ Sbjct: 260 VQTAKTNLLDELPESVLKWAPSGSSCSELVKYLMYVHNLAYDDKPDYQKLKKI 312
>P42169:YKL2_CAEEL Putative casein kinase I C03C10.2 - Caenorhabditis elegans| Length = 363 Score = 112 bits (279), Expect = 7e-24 Identities = 70/221 (31%), Positives = 123/221 (55%), Gaps = 10/221 (4%) Frame = +3 Query: 186 NKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLE-----NVKTKHPQLLYESKLYRVLQG 350 N++ + +G+G +G+I++ +V+ N+E A+K+E V TK +++ E ++ +QG Sbjct: 70 NRWSIEGVIGNGGYGQIFMVMDVKKNDERAMKIEPKLRAEVITK--RMIMEQQVLMKMQG 127 Query: 351 GTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNR----KLSLKTVLMLADQMINRVE 518 T I + G +N ++M +L ++ D F R +LS +TV +A Q +N ++ Sbjct: 128 KTHIPTMYASGFNDQFNFIIMQLLSMNVGD---FRKRSPLGRLSKETVGRIAYQTLNALK 184 Query: 519 FIHSKSFLHRDIKPDNFLMGLGKRANQV-YMIDFGLAKKYRDTSTHQHIPYRENKNLTGT 695 IH ++HRD+KP N G+ + + Y++DFGL ++++ T + IP+R N GT Sbjct: 185 DIHDMGYVHRDVKPANICFGVHAQNRHILYLLDFGLVRRFK-TESGVCIPWRINAGFKGT 243 Query: 696 ARYASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLK 818 RY SV H +EQ+ DD S+ Y + G LPW+ L+ Sbjct: 244 ERYVSVRVHEKLEQTPWDDAFSVLYTAYELVVGELPWRYLE 284
>P16913:VPK1_VACCV Serine/threonine-protein kinase 1 - Vaccinia virus (strain Western| Reserve / WR) (VACV) Length = 300 Score = 111 bits (277), Expect = 1e-23 Identities = 79/293 (26%), Positives = 140/293 (47%), Gaps = 27/293 (9%) Frame = +3 Query: 186 NKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLY-RVLQGGT-- 356 N++ +G +G G FG IY TN + +K+E + L E Y RVL+ Sbjct: 14 NQWVVGPLIGKGGFGSIYT-TN---DNNYVVKIE--PKANGSLFTEQAFYTRVLKPSVIE 67 Query: 357 -----------GISNVKWFG----VEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLML 491 G+ K FG + +Y LV++ LG L+ + N +L ++V+++ Sbjct: 68 EWKKSHNIKHVGLITCKAFGLYKSINVEYRFLVINRLGADLDAVIRANNNRLPKRSVMLI 127 Query: 492 ADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYR 671 +++N ++F+H + + H DIK N ++ + N++Y++D+GL K+ S +H+P+ Sbjct: 128 GIEILNTIQFMHEQGYSHGDIKASNIVLDQIDK-NKLYLVDYGLVSKFM--SNGEHVPFI 184 Query: 672 ENKNL--TGTARYASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLK-------AG 824 N N GT + + +H G SRR D+E+LGY ++ +L G LPW + Sbjct: 185 RNPNKMDNGTLEFTPIDSHKGYVVSRRGDLETLGYCMIRWLGGILPWTKISETKNCALVS 244 Query: 825 TKKQKYEKISERKIATSIEALCRGYPSEFQSFFHYCRSLRFEDSPDYQYLKRL 983 KQKY + + TS++ P E + SL + + P+Y + + Sbjct: 245 ATKQKYVNNTATLLMTSLQYA----PRELLQYITMVNSLTYFEEPNYDEFRHI 293
>O57252:VPK1_VACCA Serine/threonine-protein kinase 1 - Vaccinia virus (strain Ankara)| (VACV) Length = 300 Score = 111 bits (277), Expect = 1e-23 Identities = 79/293 (26%), Positives = 140/293 (47%), Gaps = 27/293 (9%) Frame = +3 Query: 186 NKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLY-RVLQGGT-- 356 N++ +G +G G FG IY TN + +K+E + L E Y RVL+ Sbjct: 14 NQWVVGPLIGKGGFGSIYT-TN---DNNYVVKIE--PKANGSLFTEQAFYTRVLKPSVIE 67 Query: 357 -----------GISNVKWFG----VEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLML 491 G+ K FG + +Y LV++ LG L+ + N +L ++V+++ Sbjct: 68 EWKKSHNIKHVGLITCKAFGLYKSINVEYRFLVINRLGADLDAVIRANNNRLPKRSVMLI 127 Query: 492 ADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYR 671 +++N ++F+H + + H DIK N ++ + N++Y++D+GL K+ S +H+P+ Sbjct: 128 GIEILNTIQFMHEQGYSHGDIKASNIVLDQIDK-NKLYLVDYGLVSKFM--SNGEHVPFI 184 Query: 672 ENKNL--TGTARYASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLK-------AG 824 N N GT + + +H G SRR D+E+LGY ++ +L G LPW + Sbjct: 185 RNPNKMDNGTLEFTPIDSHKGYVVSRRGDLETLGYCMIRWLGGILPWTKISETKNCALVS 244 Query: 825 TKKQKYEKISERKIATSIEALCRGYPSEFQSFFHYCRSLRFEDSPDYQYLKRL 983 KQKY + + TS++ P E + SL + + P+Y + + Sbjct: 245 ATKQKYVNNTATLLMTSLQYA----PRELLQYITMVNSLTYFEEPNYDKFRHI 293
>P20505:VPK1_VACCC Serine/threonine-protein kinase 1 - Vaccinia virus (strain| Copenhagen) (VACV) Length = 300 Score = 110 bits (276), Expect = 2e-23 Identities = 79/293 (26%), Positives = 140/293 (47%), Gaps = 27/293 (9%) Frame = +3 Query: 186 NKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLY-RVLQGGT-- 356 N++ +G +G G FG IY TN + +K+E + L E Y RVL+ Sbjct: 14 NQWVVGPLIGKGGFGSIYT-TN---DNNYVVKIE--PKANGSLFTEQAFYTRVLKPSVIE 67 Query: 357 -----------GISNVKWFG----VEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLML 491 G+ K FG + +Y LV++ LG L+ + N +L ++V+++ Sbjct: 68 EWKKSHNIKHVGLITCKAFGLYKSINVEYRFLVINRLGVDLDAVIRANNNRLPKRSVMLI 127 Query: 492 ADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYR 671 +++N ++F+H + + H DIK N ++ + N++Y++D+GL K+ S +H+P+ Sbjct: 128 GIEILNTIQFMHEQGYSHGDIKASNIVLDQIDK-NKLYLVDYGLVSKFM--SNGEHVPFI 184 Query: 672 ENKNL--TGTARYASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLK-------AG 824 N N GT + + +H G SRR D+E+LGY ++ +L G LPW + Sbjct: 185 RNPNKMDNGTLEFTPIDSHKGYVVSRRGDLETLGYCMIRWLGGILPWTKISETKNCALVS 244 Query: 825 TKKQKYEKISERKIATSIEALCRGYPSEFQSFFHYCRSLRFEDSPDYQYLKRL 983 KQKY + + TS++ P E + SL + + P+Y + + Sbjct: 245 ATKQKYVNNTATLLMTSLQYA----PRELLQYITMVNSLTYFEEPNYDEFRHI 293
>P33800:VPK1_VARV Serine/threonine-protein kinase 1 - Variola virus| Length = 300 Score = 109 bits (273), Expect = 4e-23 Identities = 81/294 (27%), Positives = 143/294 (48%), Gaps = 28/294 (9%) Frame = +3 Query: 186 NKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLY-RVLQGGT-- 356 N++ +G +G G FG IY TN + +K+E + L E Y RVL+ Sbjct: 14 NQWVVGPLIGKGGFGSIYT-TN---DNNYVVKIE--PKANGSLFTEQAFYTRVLKPSVIE 67 Query: 357 -----------GISNVKWFG----VEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLML 491 G+ K FG + +Y LV++ LG L+ + N +L ++V+++ Sbjct: 68 EWKKSHHISHVGVITCKAFGLYKSINTEYRFLVINRLGVDLDAVIRANNNRLPKRSVMLV 127 Query: 492 ADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYR 671 +++N ++F+H + + H +IK N ++ + N++Y++D+GL K+ S +H+P+ Sbjct: 128 GIEILNTIQFMHEQGYSHGNIKASNIVLDQMDK-NKLYLVDYGLVSKFM--SNGEHVPFI 184 Query: 672 ENKNL--TGTARYASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTK----- 830 N N GT + + +H G SRR D+E+LGY ++ +L G LPW + A TK Sbjct: 185 RNPNKMDNGTLEFTPIDSHKGYVVSRRGDLETLGYCMIRWLGGILPWTKI-AETKNCALV 243 Query: 831 ---KQKYEKISERKIATSIEALCRGYPSEFQSFFHYCRSLRFEDSPDYQYLKRL 983 KQKY + + TS++ P E + SL + + P+Y + + Sbjct: 244 SATKQKYVNNTTTLLMTSLQYA----PRELLQYITMVNSLTYFEEPNYDKFRHI 293
>P34516:YMX8_CAEEL Putative serine/threonine-protein kinase K06H7.1 - Caenorhabditis| elegans Length = 346 Score = 106 bits (265), Expect = 3e-22 Identities = 86/293 (29%), Positives = 138/293 (47%), Gaps = 7/293 (2%) Frame = +3 Query: 180 VGNKYRLGRKLGSGSFGEIY-LGTNVQTNEEVAIKLENVKTKHPQLL-YESKLYRVLQGG 353 VG +Y++ +KLG G G ++ + + + A+K+E +L E ++ L Sbjct: 16 VGKRYKVVQKLGEGGCGSVFKVEDTSEKGQHYALKVEFKSQDAGNILKMEVQILSQLISK 75 Query: 354 TGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSK 533 ++ G + Y+ +VM +LG SL+ L L++ T + + ++ ++ +H Sbjct: 76 KHVAKCVASGKKERYSYMVMTLLGESLDSLLKKHGPFLNVSTQVRIGICILFGIKQVHDI 135 Query: 534 SFLHRDIKPDNFLMGLGKRANQVY--MIDFGLAKKY---RDTSTHQHIPYRENKNLTGTA 698 +LHRD+KP N MG A++ Y ++DFGLA++Y D P RE GTA Sbjct: 136 GYLHRDLKPANVAMGCKGSADERYFLVLDFGLARQYIADEDDGLKMRRP-REKTYFRGTA 194 Query: 699 RYASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKISERKIATSI 878 RY SV+ H EQ R DD+ +L Y+L +R L W + K E I E K Sbjct: 195 RYCSVAMHDRYEQGRVDDLWALVYILAE-MRCRLAWHDV-----DDKVE-IGEMKRKIHD 247 Query: 879 EALCRGYPSEFQSFFHYCRSLRFEDSPDYQYLKRLFRDLFIREGFQFDYVFDW 1037 E L P + SF RS F PDY+ L +L D+ +++ + W Sbjct: 248 EVLFAKSPVQMLSFVKTVRSTLFYHRPDYEKLFKLLEDVMKCANYKWSDPYHW 300
>Q7KRY6:NHK1_DROME Nucleosomal histone kinase 1 - Drosophila melanogaster (Fruit fly)| Length = 599 Score = 104 bits (260), Expect = 1e-21 Identities = 115/455 (25%), Positives = 182/455 (40%), Gaps = 33/455 (7%) Frame = +3 Query: 189 KYRLGRKLGSGSFGEIYLGTNV-QTNEEVAIKLE----------------NVKTKH-PQL 314 ++R+G +G G FGEIY V + N + +K E N K + Q Sbjct: 46 QWRIGPSIGVGGFGEIYAACKVGEKNYDAVVKCEPHGNGPLFVEMHFYLRNAKLEDIKQF 105 Query: 315 LYESKL------YRVLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLK 476 + + L Y + G ++ K + +VM G L ++L Sbjct: 106 MQKHGLKSLGMPYILANGSVEVNGEK-------HRFIVMPRYGSDLTKFLEQNGKRLPEG 158 Query: 477 TVLMLADQMINRVEFIHSKSFLHRDIKPDNFLMGLGK-RANQVYMIDFGLAKKYRDTSTH 653 TV LA QM++ +++HS ++H D+K N L+GL K A Q Y++DFGLA + T Sbjct: 159 TVYRLAIQMLDVYQYMHSNGYVHADLKAANILLGLEKGGAAQAYLVDFGLASHF-VTGDF 217 Query: 654 QHIPYRENKNLTGTARYASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKK 833 + P K GT Y S HLG+ +RR D+E LGY L+ +L LPW K Sbjct: 218 KPDP---KKMHNGTIEYTSRDAHLGV-PTRRADLEILGYNLIEWLGAELPWVTQKLLAVP 273 Query: 834 QKYEKISER---KIATSIEALC-RGYPSEFQSFFHYCRSLRFEDSPDYQYLKRLF----R 989 K +K E I S++ L +G P F Y L PDY + F + Sbjct: 274 PKVQKAKEAFMDNIGESLKTLFPKGVPPPIGDFMKYVSKLTHNQEPDYDKCRSWFSSALK 333 Query: 990 DLFIREGFQFDYVFDWTILKYQQSQMTSVPPRAIAAAAGQSSGMAPIASNNRLSATEEGR 1169 L I D+ +K Q S ++ P + AA ++ A + L+++ + + Sbjct: 334 QLKIPNNGDLDFK-----MKPQTSSNNNLSPPGTSKAA--TARKAKKIDSPVLNSSLDEK 386 Query: 1170 ISGWSADPTRSQVPPTGINAGSLSKQKSPVRPDLSAPKEAVLSSSTFLGRSGVFSRRPAV 1349 IS D + S +K + + + A +S + S S++ Sbjct: 387 ISASEDDEEEEE----------KSHRKKTAKKVTPSARNAKVSPLKRVADSSPPSQKRVK 436 Query: 1350 SSSRDLPSSEAEPSRSRAPDVSPGTFQRNSAPRRA 1454 + + P A P S P +P + P A Sbjct: 437 TEPKSTPRERATPKASPKPRSTPKASPKPQTPTAA 471
>P34633:YOO1_CAEEL Putative serine/threonine-protein kinase ZK507.1 - Caenorhabditis| elegans Length = 331 Score = 94.0 bits (232), Expect = 2e-18 Identities = 58/162 (35%), Positives = 86/162 (53%), Gaps = 2/162 (1%) Frame = +3 Query: 378 FGVEGDYNVLVMDVLGPSLEDL-FSFCNRKLSLKTVLMLADQMINRVEFIHSKSFLHRDI 554 FG + +VM ++GPSLE+L + + T+L Q + + H FLHRDI Sbjct: 58 FGQSPVWKWIVMTIVGPSLEELKMKYKPSDIPPSTILQCGLQTMKAIHDFHQIGFLHRDI 117 Query: 555 KPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVSTHLGIE 734 KP N+ +G G ++ +Y++DFGLA+KYR Q P R + GT RY S ++H E Sbjct: 118 KPANYCIGYGSKSETIYVLDFGLARKYR-LPNGQVRPPRPKTKMIGTPRYCSRASHRCEE 176 Query: 735 QSRRDDMESLGYVLMYFLRGSL-PWQGLKAGTKKQKYEKISE 857 RRDD ES ++ + + +L W+GL T+ Y K E Sbjct: 177 LGRRDDYESWFFMFIDLVDTTLIDWKGL---TRPDAYAKKQE 215
>P21098:KRB2_VACCC Probable serine/threonine-protein kinase B12 - Vaccinia virus| (strain Copenhagen) (VACV) Length = 283 Score = 92.4 bits (228), Expect = 6e-18 Identities = 80/279 (28%), Positives = 126/279 (45%), Gaps = 11/279 (3%) Frame = +3 Query: 183 GNKYRLGRKLGSGSFGEIYLGTNVQTN-EEVAIKLENVKTKHPQLLYESKLYRVLQGGTG 359 G K+ +G L SG+ + N ++ +K+++ H LL E + Y + Sbjct: 12 GKKWIIGNTLYSGNSILYKVRKNFTSSFYNYVMKIDH--KSHKPLLSEIRFYISVLDPLT 69 Query: 360 ISNVKWFGVEGDYNVLVMDVLG-PSLEDLFSFCNRKLS-------LKTVLMLADQMINRV 515 I N W G + + D+ G +D F + L ++V MIN + Sbjct: 70 IDN--WTRERGIKYLAIPDLYGIGETDDYMFFVIKNLGRVFAPKDTESVFEACVTMINTL 127 Query: 516 EFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGT 695 EFIHS+ F H I+P N L+ R ++ +ID+ K S + HI Y E+ +G Sbjct: 128 EFIHSRGFTHGKIEPRNILI----RNKRLSLIDYSRTNKLYK-SGNSHIDYNEDMITSGN 182 Query: 696 ARYASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKISERKIATS 875 Y V HLG SRR D+E LGY ++ + G LPW+ ++ K K +K ++ IAT Sbjct: 183 INYMCVDNHLGATVSRRGDLEMLGYCMIEWFGGKLPWKN-ESSIKVIKQKKEYKKFIATF 241 Query: 876 IEALC--RGYPSEFQSFFHYCRSLRFEDSPDYQYLKRLF 986 E P E + +L + +P+Y L+RLF Sbjct: 242 FEDCFPEGNEPLELVRYIELVYTLDYSQTPNYDRLRRLF 280
>O57259:KRB2_VACCA Probable serine/threonine-protein kinase B12 - Vaccinia virus| (strain Ankara) (VACV) Length = 283 Score = 91.3 bits (225), Expect = 1e-17 Identities = 79/279 (28%), Positives = 126/279 (45%), Gaps = 11/279 (3%) Frame = +3 Query: 183 GNKYRLGRKLGSGSFGEIYLGTNVQTN-EEVAIKLENVKTKHPQLLYESKLYRVLQGGTG 359 G K+ +G L SG+ + N ++ +K+++ H LL E + Y + Sbjct: 12 GKKWIIGNTLYSGNSILYKVRKNFTSSFYNYVMKIDH--KSHKPLLSEIRFYISVLDPLT 69 Query: 360 ISNVKWFGVEGDYNVLVMDVLG-PSLEDLFSFCNRKLS-------LKTVLMLADQMINRV 515 I N W G + + D+ G +D F + L ++V MIN + Sbjct: 70 IDN--WTRERGIKYLAIPDLYGIGETDDYMFFVIKNLGRVFAPKDTESVFEACVTMINTL 127 Query: 516 EFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGT 695 EFIHS+ F H I+P N L+ R ++ +ID+ K S + HI Y E+ +G Sbjct: 128 EFIHSRGFTHGKIEPRNILI----RNKRLSLIDYSRTNKLYK-SGNSHIDYNEDMITSGN 182 Query: 696 ARYASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKISERKIATS 875 Y V HLG S+R D+E LGY ++ + G LPW+ ++ K K +K ++ IAT Sbjct: 183 INYMCVDNHLGATVSKRGDLEMLGYCMIEWFGGKLPWKN-ESSIKVIKQKKEYKKFIATF 241 Query: 876 IEALC--RGYPSEFQSFFHYCRSLRFEDSPDYQYLKRLF 986 E P E + +L + +P+Y L+RLF Sbjct: 242 FEDCFPEGNEPLELVRYIELVYTLDYSQTPNYDRLRRLF 280
>P24362:KRB2_VACCV Probable serine/threonine-protein kinase B12 - Vaccinia virus| (strain Western Reserve / WR) (VACV) Length = 283 Score = 90.9 bits (224), Expect = 2e-17 Identities = 79/279 (28%), Positives = 126/279 (45%), Gaps = 11/279 (3%) Frame = +3 Query: 183 GNKYRLGRKLGSGSFGEIYLGTNVQTN-EEVAIKLENVKTKHPQLLYESKLYRVLQGGTG 359 G K+ +G L SG+ + N ++ +K+++ H LL E + Y + Sbjct: 12 GKKWIIGNTLYSGNSILYKVRKNFTSSFYNYVMKIDH--KSHKPLLSEIRFYISVLDPLT 69 Query: 360 ISNVKWFGVEGDYNVLVMDVLG-PSLEDLFSFCNRKLS-------LKTVLMLADQMINRV 515 I N W G + + D+ G +D F + L ++V MIN + Sbjct: 70 IDN--WTRERGIKYLAIPDLYGIGETDDYMFFVIKNLGRVFAPKDTESVFEACVTMINTL 127 Query: 516 EFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGT 695 EFIHS+ F H I+P N L+ R ++ +ID+ K S + HI Y E+ +G Sbjct: 128 EFIHSQGFTHGKIEPRNILI----RNKRLSLIDYSRTNKLYK-SGNSHIDYNEDMITSGN 182 Query: 696 ARYASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKISERKIATS 875 Y V HLG SRR D+E LGY ++ + G LPW+ ++ K K +K ++ IAT Sbjct: 183 INYMCVDNHLGATVSRRGDLEMLGYCMIEWFGGKLPWKN-ESSIKVIKQKKEYKKFIATF 241 Query: 876 IEALC--RGYPSEFQSFFHYCRSLRFEDSPDYQYLKRLF 986 E P E + +L + +P+Y L++LF Sbjct: 242 FEDCFPEGNEPLELVRYIELVYTLDYSQTPNYDRLRKLF 280
>Q09503:YQI1_CAEEL Uncharacterized protein C45G9.1 - Caenorhabditis elegans| Length = 290 Score = 87.8 bits (216), Expect = 1e-16 Identities = 71/272 (26%), Positives = 123/272 (45%), Gaps = 12/272 (4%) Frame = +3 Query: 360 ISNVKWFGVEGDYNVLVMDVLGPSLEDLFS---FCNRKLSLKTVLMLADQMINRVEFIHS 530 I N+ +G + +++ +VM +LG +L+DL S N+ S T + Q + ++++H Sbjct: 18 IPNLNLYGKKMNFSYMVMTLLGRNLQDLESTNFVVNKGFSRGTWSRVGIQWVYALKYVHY 77 Query: 531 KSFLHRDIKPDNFLMGLGK---RANQVYMIDFGLAKKY-----RDTSTHQHIPYRENKNL 686 F+HR++ N +G K RA ++++DFGL + + R+ I R + Sbjct: 78 NGFIHRNVNTQNLFLGNEKDSERAKIIHILDFGLGRPFARYHARENKWIVRIA-RHSAEF 136 Query: 687 TGTARYASVSTHLGIEQSRRDDMESLGYVLMYFLRG-SLPWQGLKAGTKKQKYEKISERK 863 G+ RYAS + HL EQ R DD+ SL YV++ G +LPWQ + ++ + K Sbjct: 137 RGSFRYASPNVHLRKEQGRVDDVWSLPYVIIELNGGKALPWQ------TDYRRGRVEQMK 190 Query: 864 IATSIEALCRGYPSEFQSFFHYCRSLRFEDSPDYQYLKRLFRDLFIREGFQFDYVFDWTI 1043 + + + + P+ + SL + PD + + F + E FDW Sbjct: 191 LNLTPKDVMSDMPACMDKLMPHLASLNYYQRPDDHMIFKCFWQVMENEKITPSSKFDWE- 249 Query: 1044 LKYQQSQMTSVPPRAIAAAAGQSSGMAPIASN 1139 + SVPP A G+ P+ N Sbjct: 250 ---NEEPDMSVPPAAWENPDGRYFQSNPLEIN 278
>P54736:PKN2_MYXXA Serine/threonine-protein kinase pkn2 - Myxococcus xanthus| Length = 830 Score = 85.1 bits (209), Expect = 9e-16 Identities = 65/215 (30%), Positives = 100/215 (46%), Gaps = 7/215 (3%) Frame = +3 Query: 189 KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQ------LLYESKLYRVLQG 350 ++R+ R LGSG GE+YLG V +VAIK+ + H Q E++L ++ Sbjct: 12 RFRVLRPLGSGGMGEVYLGEQVSLGRKVAIKVLH-HDLHAQAGMAERFKREARLLSAVEH 70 Query: 351 GTGISNVKWFGVEGDYNVLVMD-VLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIH 527 + V FG GD+ LVM+ V G SL D+ + + L L Q+ + IH Sbjct: 71 PAVVRIVD-FGESGDHACLVMEFVEGESLYDVLT--PGPMPPGRALPLLQQLAEGLAAIH 127 Query: 528 SKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYA 707 K +HRD+KP+N + R Q ++DFG+A+ + + + GT Y Sbjct: 128 DKGIIHRDLKPENVFISKSARGEQARLLDFGIARLVEPDAASS---VSQIGVVLGTPEYL 184 Query: 708 SVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQG 812 S +G + R D+ S G + L G LP+ G Sbjct: 185 SPEQAVGAKVDTRSDLYSFGVLTYRVLSGRLPFDG 219
>P33973:PKN1_MYXXA Serine/threonine-protein kinase pkn1 - Myxococcus xanthus| Length = 693 Score = 82.8 bits (203), Expect = 5e-15 Identities = 73/252 (28%), Positives = 119/252 (47%), Gaps = 13/252 (5%) Frame = +3 Query: 105 P*LDALNLGGGSVACVRARPPME---PRVG---NKYRLGRKLGSGSFGEIYLGTNVQTNE 266 P L ++ G A R P +E P VG +RL R+LG G G +YLG +V Sbjct: 24 PTLVRADVRAGGTAHPRCAPVVEAQDPLVGVRCGSFRLVRRLGRGGMGAVYLGEHVSIGS 83 Query: 267 EVAIKLENVK-TKHPQLL--YESKLYRV-LQGGTGISNVKWFGVEGDYNVLVMDVLGPSL 434 VA+K+ + T +P+L+ + ++ V L G I ++ L+M+ L + Sbjct: 84 RVAVKVLHAHLTMYPELVQRFHAEARAVNLIGHENIVSIFDMDATPPRPYLIMEFLDGA- 142 Query: 435 EDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFLHRDIKPDN-FLMGLGKRANQVYMI 611 L ++ L+ V+ + Q+ + ++ H++ +HRD+KPDN FL+ A V ++ Sbjct: 143 -PLSAWVGTPLAAGAVVSVLSQVCDALQAAHARGIVHRDLKPDNIFLVRRNGNAPFVKVL 201 Query: 612 DFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVSTHLGIEQSRRDDMESLGYVLMYFLR 791 DFG+AK H+P + GT Y + LG R D+ +LG + L Sbjct: 202 DFGIAK-----LADAHMPQTHAGIIVGTPEYMAPEQSLGRGVDGRADLYALGVIAYQLLT 256 Query: 792 GSLPW--QGLKA 821 G LP+ +GL A Sbjct: 257 GRLPFNDEGLAA 268
>P34635:YOO3_CAEEL Putative serine/threonine-protein kinase ZK507.3 - Caenorhabditis| elegans Length = 374 Score = 82.0 bits (201), Expect = 8e-15 Identities = 75/299 (25%), Positives = 131/299 (43%), Gaps = 21/299 (7%) Frame = +3 Query: 378 FGVEGDYNVLVMDVLGPSLEDL-FSFCNRKLSLKTVLMLADQMINRVEFIHSKSFLHRDI 554 FG + +VM ++GPSLE+L + + T+L Q + + H FLHRDI Sbjct: 100 FGQSPVWKWIVMTIVGPSLEELKMKYKPSDIPPSTILQCGLQTMKAIHDFHQIGFLHRDI 159 Query: 555 KPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVSTHLGIE 734 KP N+ +G G ++ +Y++DFGLA+KYR +P Y S ++H E Sbjct: 160 KPANYCIGYGSKSETIYVLDFGLARKYR-------LP----------EWYCSRASHRCEE 202 Query: 735 QSRRDDMESLGYVLMYFLRGSL-PWQGLKAGTKKQKYEKISERKIATSIEALCRGYPSE- 908 RRDD ES ++ + + +L W+GL T+ Y K ++++ T ++ Y E Sbjct: 203 LGRRDDYESWFFMFIDLVDTTLIDWKGL---TRPDAYAK--KQELFTKLKT----YEKEP 253 Query: 909 -FQSFFHYCRSLRFEDSPDYQYLKRLFRDLFIREGFQFDYVFDWTILKYQQSQMTSVPPR 1085 F+ Y +L ++ + +L+ D W + ++ S P Sbjct: 254 MFKVISIYLDTLVYDSDVKFGFLRDAITDYARSCKLTLKEPLVW-FKERNDNESGSTPTT 312 Query: 1086 AIAAAA-------GQSSGMAPIASN----------NRLSATEEGRISGWSADPTRSQVP 1211 + A + G +G++ IASN N ++ + + W + TR++ P Sbjct: 313 SATACSPSSSTGTGTGTGVSKIASNIDQKSIASDRNEENSLDGSKTGTWKSTKTRNKKP 371
>Q8K3G5:VRK3_MOUSE Serine/threonine-protein kinase VRK3 - Mus musculus (Mouse)| Length = 453 Score = 81.3 bits (199), Expect = 1e-14 Identities = 59/212 (27%), Positives = 103/212 (48%), Gaps = 12/212 (5%) Frame = +3 Query: 378 FGVEGD-YNVLVMDVLGPSLED-LFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFLHRD 551 FG+ D Y LV LG SL+ L +S + VL +A ++++ +E++H ++H + Sbjct: 226 FGIHQDKYRFLVFPSLGRSLQSALDDNPKHVVSERCVLQVACRLLDALEYLHENEYVHGN 285 Query: 552 IKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLT--GTARYASVSTHL 725 + +N + + +QV ++ +G YR +H+ Y+E G + S+ H Sbjct: 286 LTAENVFVN-PEDLSQVTLVGYGFT--YRYCPGGKHVAYKEGSRSPHDGDLEFISMDLHK 342 Query: 726 GIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGT-----KKQKYEKISERKIATSIEALC 890 G SRR D+++LGY ++ +L GSLPW T +KQKY ER + LC Sbjct: 343 GCGPSRRSDLQTLGYCMLKWLYGSLPWTNCLPNTEKITRQKQKYLDSPERLV-----GLC 397 Query: 891 RGYPSEFQSFFHYCR---SLRFEDSPDYQYLK 977 + ++ Y + +L +E+ P Y L+ Sbjct: 398 GRWNKASETLREYLKVVMALNYEEKPPYATLR 429
>Q9J509:V226_FOWPV Probable serine/threonine-protein kinase FPV226 - Fowlpox virus| (FPV) Length = 292 Score = 80.1 bits (196), Expect = 3e-14 Identities = 69/294 (23%), Positives = 124/294 (42%), Gaps = 17/294 (5%) Frame = +3 Query: 165 PMEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVK--TKHPQLLYESKLY- 335 P+ G ++++ + +G G FG +Y + IK+E++ T ++L + +Y Sbjct: 5 PLIDIYGKQWKIDKLIGCGGFGCVYSTQCASNTRQAVIKVESLNNTTMVSEVLVYNNIYD 64 Query: 336 -RVLQGGTGISNVKWFGVE-----GD-------YNVLVMDVLGPSLEDLFSFCNRKLSLK 476 + N+ G+ G Y ++++ L + ++L + L Sbjct: 65 KNRIALWKNYKNIDHLGIPMYYGCGSFKRNTMYYRFILLERLVENTKELLKRVKKPKPLI 124 Query: 477 TVLMLADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQ 656 +M M+ +E+IH H DIKP+N ++ R+ Y+ID+G+ + H Sbjct: 125 KNIM--KDMLYTLEYIHEHGISHGDIKPENIMVDGRYRS---YLIDYGIVSYFIVNGKHV 179 Query: 657 HIPYRENKNL-TGTARYASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKK 833 Y+E+KN GT YAS+ H G +RR D+ESLGY ++ + LPW+ Sbjct: 180 KY-YKESKNWHRGTLYYASLDAHNGTCVTRRGDLESLGYCMLKWAGIPLPWKVFGNNGNM 238 Query: 834 QKYEKISERKIATSIEALCRGYPSEFQSFFHYCRSLRFEDSPDYQYLKRLFRDL 995 K K + + + L +E+ PDY L++L L Sbjct: 239 VHVAKCDFIKRVHKNKVNIKSANKGIYDYIKCVTKLSYEEKPDYDLLRQLVNSL 292
>O34507:PRKC_BACSU Serine/threonine-protein kinase prkC - Bacillus subtilis| Length = 648 Score = 79.3 bits (194), Expect = 5e-14 Identities = 80/346 (23%), Positives = 143/346 (41%), Gaps = 11/346 (3%) Frame = +3 Query: 177 RVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGT 356 R+ +Y++ R +G G +YL ++ + EVAIK+ + + R Q + Sbjct: 6 RISGRYQILRVIGGGGMANVYLAEDIILDREVAIKILRFDYANDNEFIR-RFRREAQSAS 64 Query: 357 GISN-----VKWFGVEGDYNVLVMD-VLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVE 518 + + + G E D +VM+ V G +L++ + N L K L + +Q+++ + Sbjct: 65 SLDHPNIVSIYDLGEEDDIYYIVMEYVEGMTLKEYIT-ANGPLHPKEALNIMEQIVSAIA 123 Query: 519 FIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTS-THQHIPYRENKNLTGT 695 H +HRDIKP N L+ + + DFG+A T+ TH ++ G+ Sbjct: 124 HAHQNQIVHRDIKPHNILI---DHMGNIKVTDFGIATALSSTTITH-------TNSVLGS 173 Query: 696 ARYASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKISERKIATS 875 Y S G +++ D+ +LG VL L G +P+ G A I+ + + Sbjct: 174 VHYLSPEQARGGLATKKSDIYALGIVLFELLTGRIPFDGESA-------VSIALKHLQAE 226 Query: 876 IEALCRGYPSEFQSFFHYCRSLRFEDSPDYQYLKRLFRDLFIREGFQFDYVFDWTILKYQ 1055 + R PS QS + +D P ++Y + I+ F D + + + Sbjct: 227 TPSAKRWNPSVPQSVENIILKATAKD-PFHRYETAEDMEADIKTAFDADRLNEKRFTIQE 285 Query: 1056 QSQMTSVPP----RAIAAAAGQSSGMAPIASNNRLSATEEGRISGW 1181 +MT P +A AAG+ A N+ + G+ W Sbjct: 286 DEEMTKAIPIIKDEELAKAAGEKEAEVTTAQENK--TKKNGKRKKW 329
>Q8IV63:VRK3_HUMAN Serine/threonine-protein kinase VRK3 - Homo sapiens (Human)| Length = 474 Score = 79.0 bits (193), Expect = 7e-14 Identities = 60/210 (28%), Positives = 103/210 (49%), Gaps = 10/210 (4%) Frame = +3 Query: 378 FGVEGD-YNVLVMDVLGPSLEDLFSFCNRK-LSLKTVLMLADQMINRVEFIHSKSFLHRD 551 FGV D Y LV+ LG SL+ + LS ++VL +A ++++ +EF+H ++H + Sbjct: 247 FGVHQDKYRFLVLPSLGRSLQSALDVSPKHVLSERSVLQVACRLLDALEFLHENEYVHGN 306 Query: 552 IKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLT--GTARYASVSTHL 725 + +N + + +QV + +G A +Y + +H+ Y E G + S+ H Sbjct: 307 VTAENIFVD-PEDQSQVTLAGYGFAFRYCPSG--KHVAYVEGSRSPHEGDLEFISMDLHK 363 Query: 726 GIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTK---KQKYEKISERKIATSIEALCRG 896 G SRR D++SLGY ++ +L G LPW T+ KQK + + + C Sbjct: 364 GCGPSRRSDLQSLGYCMLKWLYGFLPWTNCLPNTEDIMKQKQKFVDK---PGPFVGPCGH 420 Query: 897 Y--PSE-FQSFFHYCRSLRFEDSPDYQYLK 977 + PSE Q + +L +E+ P Y L+ Sbjct: 421 WIRPSETLQKYLKVVMALTYEEKPPYAMLR 450
>Q8R9T6:PKN1_THETN Probable serine/threonine-protein kinase Sps1 - Thermoanaerobacter| tengcongensis Length = 625 Score = 79.0 bits (193), Expect = 7e-14 Identities = 63/217 (29%), Positives = 100/217 (46%), Gaps = 6/217 (2%) Frame = +3 Query: 180 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTG 359 +GN+Y + K+G G ++Y N VAIK+ + + + K R Q Sbjct: 6 LGNRYEILEKIGEGGMAKVYKAKCHLLNRIVAIKILRPEFAADEN-FVKKFKRESQAAAS 64 Query: 360 ISNVKWFGV-----EGDYNVLVMD-VLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEF 521 +S+ G+ EGD +VM+ V G +L++L L +K + +A Q+ ++ Sbjct: 65 LSHPNIVGIYDVGQEGDIYYIVMEYVKGRTLKELIRENGGPLEVKRAVEIASQVCRALDH 124 Query: 522 IHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTAR 701 H +HRDIKP N L+ + V + DFG+A+ + I Y ++ GTA Sbjct: 125 AHKNKIIHRDIKPQNILV---TDEDVVKVTDFGIARAANGAT----ITY--TGDVIGTAY 175 Query: 702 YASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQG 812 Y S G R D+ SLG VL L G +P++G Sbjct: 176 YFSPEQAKGSIVDERTDIYSLGIVLFEMLTGKVPFEG 212
>O84303:PKND_CHLTR Serine/threonine-protein kinase pknD - Chlamydia trachomatis| Length = 934 Score = 77.8 bits (190), Expect = 1e-13 Identities = 71/264 (26%), Positives = 119/264 (45%), Gaps = 38/264 (14%) Frame = +3 Query: 189 KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK-----LENVKTKHPQLLYESKL------- 332 +Y L R +G G GE+YL + + VA+K L + L E+K+ Sbjct: 3 RYELIRLIGKGGMGEVYLAHDKACSRRVALKRIREDLSGNALLRQRFLREAKIAADLIHP 62 Query: 333 -----YRVLQGGTGI----SNVKWFGVEGDY-NVLVMDVLGPSLEDLFSFCNRKLSLKTV 482 Y + G + ++ F ++ +V +VL LE+ K S+K+ Sbjct: 63 GIVPVYSICSDGEAVYYTMPYIEGFSLKSLLKSVWQKEVLSKELEE-------KTSVKSF 115 Query: 483 LMLADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLA--KKYRDTSTHQ 656 L + D++ VE+IHSK LHRD+KPDN L+GL +V +ID+G A K ++ Q Sbjct: 116 LPIFDKICATVEYIHSKGVLHRDLKPDNILLGL---FGEVVIIDWGAAIFKHAKELKLEQ 172 Query: 657 H----IPYRENK----------NLTGTARYASVSTHLGIEQSRRDDMESLGYVLMYFLRG 794 + + E + GT Y + + LG+E S + D+ +LG +L L Sbjct: 173 DDEAAVSFDERNICYSSMTIPGKIVGTPDYMAPESLLGVEASEKTDIYALGLILYQMLTL 232 Query: 795 SLPWQGLKAGTKKQKYEKISERKI 866 + P+ +++K K+S R + Sbjct: 233 AFPY-------RRKKGRKLSYRDV 249
>Q3KM61:PKND_CHLTA Serine/threonine-protein kinase pknD - Chlamydia trachomatis| (strain A/HAR-13 / ATCC VR-571B) Length = 934 Score = 77.8 bits (190), Expect = 1e-13 Identities = 71/264 (26%), Positives = 119/264 (45%), Gaps = 38/264 (14%) Frame = +3 Query: 189 KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK-----LENVKTKHPQLLYESKL------- 332 +Y L R +G G GE+YL + + VA+K L + L E+K+ Sbjct: 3 RYELIRLIGKGGMGEVYLAHDKACSRRVALKRIREDLSGNALLRQRFLREAKIAADLIHP 62 Query: 333 -----YRVLQGGTGI----SNVKWFGVEGDY-NVLVMDVLGPSLEDLFSFCNRKLSLKTV 482 Y + G + ++ F ++ +V +VL LE+ K S+K+ Sbjct: 63 GIVPVYSICSDGEAVYYTMPYIEGFSLKSLLKSVWQKEVLSKELEE-------KTSVKSF 115 Query: 483 LMLADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLA--KKYRDTSTHQ 656 L + D++ VE+IHSK LHRD+KPDN L+GL +V +ID+G A K ++ Q Sbjct: 116 LPIFDKICATVEYIHSKGVLHRDLKPDNILLGL---FGEVVIIDWGAAIFKHAKELKLEQ 172 Query: 657 H----IPYRENK----------NLTGTARYASVSTHLGIEQSRRDDMESLGYVLMYFLRG 794 + + E + GT Y + + LG+E S + D+ +LG +L L Sbjct: 173 DDEAAVSFDERNICYSSMTIPGKIVGTPDYMAPESLLGVEASEKTDIYALGLILYQMLTL 232 Query: 795 SLPWQGLKAGTKKQKYEKISERKI 866 + P+ +++K K+S R + Sbjct: 233 AFPY-------RRKKGRKLSYRDV 249
>Q9PK92:PKND_CHLMU Serine/threonine-protein kinase pknD - Chlamydia muridarum| Length = 934 Score = 77.0 bits (188), Expect = 3e-13 Identities = 71/258 (27%), Positives = 113/258 (43%), Gaps = 39/258 (15%) Frame = +3 Query: 189 KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK-----LENVKTKHPQLLYESKL------- 332 +Y L R +G G GE+YL + + VA+K L + + L E+K+ Sbjct: 3 RYELIRLIGRGGMGEVYLAHDKACSRRVALKKIREDLSDNPLLRKRFLREAKIAADLIHP 62 Query: 333 -----YRVLQGGTGISNVKWFGVEGDY------NVLVMDVLGPSLEDLFSFCNRKLSLKT 479 Y + G + + +EG +V ++L LE+ K S+K Sbjct: 63 GIVPVYSICSDGESVYYTMPY-IEGFSLKHLLKSVWQKEILSKELEE-------KTSVKA 114 Query: 480 VLMLADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL-----AKKYRDT 644 L + D++ VE+IHSK LHRD+KPDN L+GL +V ++D+G AK+ + Sbjct: 115 FLPIFDKICATVEYIHSKGVLHRDLKPDNILLGL---FGEVVIVDWGAAIFKHAKELQQE 171 Query: 645 STHQHIPYRENKN-----------LTGTARYASVSTHLGIEQSRRDDMESLGYVLMYFLR 791 + KN + GT Y + + LG E S + D+ +LG +L L Sbjct: 172 KDEEGFSSYGQKNICYSSMTVPGKIVGTPDYMAPESLLGAEASEKTDIYALGLILYQMLT 231 Query: 792 GSLPWQGLKAGTKKQKYE 845 S P++ K +K YE Sbjct: 232 LSFPYRRKKG--RKLPYE 247
>Q8CIP4:MARK4_MOUSE MAP/microtubule affinity-regulating kinase 4 - Mus musculus (Mouse)| Length = 752 Score = 75.1 bits (183), Expect = 1e-12 Identities = 66/236 (27%), Positives = 115/236 (48%), Gaps = 6/236 (2%) Frame = +3 Query: 123 NLGGGSVACVRARPPMEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTK 302 +LG + + P +P VGN YRL R +G G+F ++ L ++ T EVAIK+ + Sbjct: 37 SLGARCRNSIASCPEEQPHVGN-YRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQL 95 Query: 303 HPQLLYESKLYRVLQGGTGISN---VKWFGVEGDYNVLVMDVLGPSLEDLFSF--CNRKL 467 +P L KL+R ++ G+++ VK F V L + + S ++F + + ++ Sbjct: 96 NPSSL--QKLFREVRIMKGLNHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRM 153 Query: 468 SLKTVLMLADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTS 647 K Q+++ V + H K+ +HRD+K +N L L AN + + DFG + ++ S Sbjct: 154 KEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLL--LDAEAN-IKIADFGFSNEFTLGS 210 Query: 648 THQHIPYRENKNLTGTARYASVSTHLGIEQSRRD-DMESLGYVLMYFLRGSLPWQG 812 + G+ YA+ G + + D+ SLG +L + GSLP+ G Sbjct: 211 --------KLDTFCGSPPYAAPELFQGKKYDGPEVDIWSLGVILYTLVSGSLPFDG 258
>Q96L34:MARK4_HUMAN MAP/microtubule affinity-regulating kinase 4 - Homo sapiens (Human)| Length = 752 Score = 75.1 bits (183), Expect = 1e-12 Identities = 66/236 (27%), Positives = 115/236 (48%), Gaps = 6/236 (2%) Frame = +3 Query: 123 NLGGGSVACVRARPPMEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTK 302 +LG + + P +P VGN YRL R +G G+F ++ L ++ T EVAIK+ + Sbjct: 37 SLGARCRNSIASCPEEQPHVGN-YRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQL 95 Query: 303 HPQLLYESKLYRVLQGGTGISN---VKWFGVEGDYNVLVMDVLGPSLEDLFSF--CNRKL 467 +P L KL+R ++ G+++ VK F V L + + S ++F + + ++ Sbjct: 96 NPSSL--QKLFREVRIMKGLNHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRM 153 Query: 468 SLKTVLMLADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTS 647 K Q+++ V + H K+ +HRD+K +N L L AN + + DFG + ++ S Sbjct: 154 KEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLL--LDAEAN-IKIADFGFSNEFTLGS 210 Query: 648 THQHIPYRENKNLTGTARYASVSTHLGIEQSRRD-DMESLGYVLMYFLRGSLPWQG 812 + G+ YA+ G + + D+ SLG +L + GSLP+ G Sbjct: 211 --------KLDTFCGSPPYAAPELFQGKKYDGPEVDIWSLGVILYTLVSGSLPFDG 258
>P65726:PKNA_MYCTU Probable serine/threonine-protein kinase pknA - Mycobacterium| tuberculosis Length = 431 Score = 74.7 bits (182), Expect = 1e-12 Identities = 69/242 (28%), Positives = 112/242 (46%), Gaps = 15/242 (6%) Frame = +3 Query: 168 MEPRVG----NKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK-LENVKTKHPQLLYESKL 332 M PRVG +YRL R + +G G+++ + + VA+K L++ + P+ + + Sbjct: 1 MSPRVGVTLSGRYRLQRLIATGGMGQVWEAVDNRLGRRVAVKVLKSEFSSDPEFIERFRA 60 Query: 333 YR---VLQGGTGISNVKWFGV-----EGDYNVLVMDVLGPSLEDLFSFCNR--KLSLKTV 482 + GI++V +G EG LVM+++ E L S R +LSL+ Sbjct: 61 EARTTAMLNHPGIASVHDYGESQMNGEGRTAYLVMELVNG--EPLNSVLKRTGRLSLRHA 118 Query: 483 LMLADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHI 662 L + +Q ++ H+ +HRD+KP N L+ QV + DFG+AK Sbjct: 119 LDMLEQTGRALQIAHAAGLVHRDVKPGNILI---TPTGQVKITDFGIAKAV------DAA 169 Query: 663 PYRENKNLTGTARYASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKY 842 P + + GTA+Y + LG + S D+ SLG V + G P+ G A T K+ Sbjct: 170 PVTQTGMVMGTAQYIAPEQALGHDASPASDVYSLGVVGYEAVSGKRPFAGDGALTVAMKH 229 Query: 843 EK 848 K Sbjct: 230 IK 231
>P65727:PKNA_MYCBO Probable serine/threonine-protein kinase pknA - Mycobacterium bovis| Length = 431 Score = 74.7 bits (182), Expect = 1e-12 Identities = 69/242 (28%), Positives = 112/242 (46%), Gaps = 15/242 (6%) Frame = +3 Query: 168 MEPRVG----NKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK-LENVKTKHPQLLYESKL 332 M PRVG +YRL R + +G G+++ + + VA+K L++ + P+ + + Sbjct: 1 MSPRVGVTLSGRYRLQRLIATGGMGQVWEAVDNRLGRRVAVKVLKSEFSSDPEFIERFRA 60 Query: 333 YR---VLQGGTGISNVKWFGV-----EGDYNVLVMDVLGPSLEDLFSFCNR--KLSLKTV 482 + GI++V +G EG LVM+++ E L S R +LSL+ Sbjct: 61 EARTTAMLNHPGIASVHDYGESQMNGEGRTAYLVMELVNG--EPLNSVLKRTGRLSLRHA 118 Query: 483 LMLADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHI 662 L + +Q ++ H+ +HRD+KP N L+ QV + DFG+AK Sbjct: 119 LDMLEQTGRALQIAHAAGLVHRDVKPGNILI---TPTGQVKITDFGIAKAV------DAA 169 Query: 663 PYRENKNLTGTARYASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKY 842 P + + GTA+Y + LG + S D+ SLG V + G P+ G A T K+ Sbjct: 170 PVTQTGMVMGTAQYIAPEQALGHDASPASDVYSLGVVGYEAVSGKRPFAGDGALTVAMKH 229 Query: 843 EK 848 K Sbjct: 230 IK 231
>Q97IC2:PKN2_CLOAB Probable serine/threonine protein kinase CA_C1728 - Clostridium| acetobutylicum Length = 657 Score = 74.7 bits (182), Expect = 1e-12 Identities = 55/214 (25%), Positives = 98/214 (45%), Gaps = 5/214 (2%) Frame = +3 Query: 180 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK-LENVKTKHPQLLYESKLYRVLQG-- 350 + N+Y++ ++G G +Y + N VA+K L++ T+ + +++ K Sbjct: 6 LSNRYKIEEEIGVGGTAVVYKAMDTLLNRHVAVKVLKHEFTEDEEFVFKFKREASAAARI 65 Query: 351 -GTGISNVKWFGVEGDYNVLVMD-VLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFI 524 I N+ G +G+ N +VM+ V G +L+ L N K+ ++ A Q+ + F Sbjct: 66 ANANIVNIYDVGADGNVNYIVMEYVAGKTLKKLIKE-NGKIEFNKIIDYATQIAKALNFA 124 Query: 525 HSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARY 704 H +HRDIKP N ++ + + + DFG+AK +++ + G+A Y Sbjct: 125 HKNGIVHRDIKPHNIMV---TDDDIIKVTDFGIAKASNEST------ITTTNKVVGSAHY 175 Query: 705 ASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPW 806 S GI R D+ S G VL G +P+ Sbjct: 176 LSPEQAQGIPVDCRTDIYSFGIVLYEMATGKVPY 209
>Q8G6P9:PKNB_BIFLO Probable serine/threonine-protein kinase pknB - Bifidobacterium| longum Length = 690 Score = 74.3 bits (181), Expect = 2e-12 Identities = 68/259 (26%), Positives = 116/259 (44%), Gaps = 14/259 (5%) Frame = +3 Query: 183 GNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLL---YESKLYRVLQ-G 350 G +Y+LG+ +G G E+++ + + VA+K+ + + + + + V Q Sbjct: 11 GGRYQLGQLIGRGGMAEVHVALDTRLGRTVAVKIMRADLANDDIFLARFRREAHAVAQMN 70 Query: 351 GTGISNVKWFGVE------GDYN---VLVMD-VLGPSLEDLFSFCNRKLSLKTVLMLADQ 500 I N+ G E GD +VM+ V G +L D+ N LS + + Sbjct: 71 NPNIVNIYDSGEELVSSESGDAERLPYIVMEYVKGQTLRDIIK-VNGALSQRDCEQVMLG 129 Query: 501 MINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENK 680 ++N +++ H +HRDIKP N ++ V ++DFG+A+ D++ +++ Sbjct: 130 VLNALDYSHRMGIIHRDIKPGNIMI---SEQGVVKVMDFGIARALDDSAA----TMTQSQ 182 Query: 681 NLTGTARYASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKISER 860 + GTA+Y S G R D+ S G VL L G P+ G A Y+ +SE Sbjct: 183 GVVGTAQYLSPEQARGETVDMRSDLYSAGCVLYEMLTGRPPFTGDSA--VAIAYQHVSE- 239 Query: 861 KIATSIEALCRGYPSEFQS 917 +AT A G P + S Sbjct: 240 -VATPPSAAVPGLPKMWDS 257
>O59790:ARK1_SCHPO Serine/threonine-protein kinase ark1 - Schizosaccharomyces pombe| (Fission yeast) Length = 355 Score = 73.6 bits (179), Expect = 3e-12 Identities = 60/227 (26%), Positives = 101/227 (44%), Gaps = 11/227 (4%) Frame = +3 Query: 192 YRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTGI-SN 368 + +G+ LG G FG +YL +T VA+K T H L +SK+ + ++ I SN Sbjct: 89 FEIGKPLGKGKFGRVYLAKEKKTGFIVALK-----TLHKSELVQSKIEKQVRREIEIQSN 143 Query: 369 VKWFGVEGDYN--------VLVMDVLGPSLEDLFSFCNR--KLSLKTVLMLADQMINRVE 518 ++ + Y L+++ G +L+ R + S + QM N + Sbjct: 144 LRHKNILRLYGHFHDEKRIYLILEFAGRG--ELYQHLRRAKRFSEEVASKYIFQMANALS 201 Query: 519 FIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTA 698 ++H K +HRDIKP+N L+G+ ++ + DFG + H P L GT Sbjct: 202 YLHKKHVIHRDIKPENILLGID---GEIKLSDFGWS---------VHAPSNRRTTLCGTL 249 Query: 699 RYASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQK 839 Y G E + + D+ SLG + FL G+ P++ + + K Sbjct: 250 DYLPPEMVEGKEHTEKVDLWSLGVLTYEFLVGAPPFEDMSGHSATYK 296
>P54743:PKNA_MYCLE Probable serine/threonine-protein kinase pknA - Mycobacterium| leprae Length = 437 Score = 73.2 bits (178), Expect = 4e-12 Identities = 66/242 (27%), Positives = 111/242 (45%), Gaps = 15/242 (6%) Frame = +3 Query: 168 MEPRVG----NKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK-LENVKTKHPQLLYESKL 332 M PR+G +YRL R + +G G+++ + + VA+K L+ + P+ + + Sbjct: 1 MSPRIGVMLSGRYRLHRLIATGGMGQVWEAVDSRLGRRVAVKVLKGEFSSDPEFIERFRA 60 Query: 333 YR---VLQGGTGISNVKWFGV-----EGDYNVLVMDVLGPSLEDLFSFCNR--KLSLKTV 482 + GI++V +G EG LVM+++ E L S R +LSL+ Sbjct: 61 EARTTAMLNHPGIASVHDYGESHMDGEGRTAYLVMELVNG--EPLNSVLKRTGRLSLRHA 118 Query: 483 LMLADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHI 662 L + +Q ++ H+ +HRD+KP N L+ QV + DFG+AK Sbjct: 119 LDMLEQTGRALQIAHAAGLVHRDVKPGNILI---TPTGQVKITDFGIAKAV------DAA 169 Query: 663 PYRENKNLTGTARYASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKY 842 P + + GTA+Y + LG + + D+ SLG + + G P+ G A T K+ Sbjct: 170 PVTQTGMVMGTAQYIAPEQALGHDATPASDVYSLGVIGYEVVSGKRPFTGDGALTVAMKH 229 Query: 843 EK 848 K Sbjct: 230 IK 231
>Q8XJL8:PKN2_CLOPE Probable serine/threonine protein kinase CPE1738 - Clostridium| perfringens Length = 685 Score = 72.4 bits (176), Expect = 6e-12 Identities = 58/216 (26%), Positives = 100/216 (46%), Gaps = 5/216 (2%) Frame = +3 Query: 180 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLL---YESKLYRVLQ- 347 +GN+Y L + +G G +Y + N VA+K+ + K+ + + ++ + + Sbjct: 6 LGNRYELLQCVGEGGMSFVYKARCRKLNRFVAVKILKDEFKNNEEIVRRFKKEATAIANL 65 Query: 348 GGTGISNVKWFGVEGDYNVLVMD-VLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFI 524 + NV G + D N +VM+ V G +L+D+ L + + + ++ +E Sbjct: 66 SNPNVVNVLDVGTQDDINYIVMEYVEGKTLKDIIKE-KGALPYEVAISIGIKVAKALECA 124 Query: 525 HSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARY 704 H +HRD+KP N L+ V + DFG+AK D+ST H ++ G+A Y Sbjct: 125 HKSGIIHRDVKPQNILV---TEEGVVKVTDFGIAKS-MDSSTIAH-----TNSVMGSAHY 175 Query: 705 ASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQG 812 S G R D+ SLG VL + G +P+ G Sbjct: 176 FSPEQAKGTYTDYRTDLYSLGIVLYEMVTGVVPFNG 211
>Q17850:PAK1_CAEEL Serine/threonine-protein kinase pak-1 - Caenorhabditis elegans| Length = 572 Score = 72.0 bits (175), Expect = 8e-12 Identities = 55/214 (25%), Positives = 101/214 (47%), Gaps = 5/214 (2%) Frame = +3 Query: 180 VGN---KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKT--KHPQLLYESKLYRVL 344 +GN KYR K+GSG+ G +Y + T EVAIK N+K K ++ E + R Sbjct: 288 IGNPDRKYRKVDKIGSGASGSVYTAIEISTEAEVAIKQMNLKDQPKKELIINEILVMREN 347 Query: 345 QGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFI 524 + ++ + + V + V++ + G SL D+ + C + + + + +++ +EF+ Sbjct: 348 KHANIVNYLDSYLVCDELWVVMEYLAGGSLTDVVTECQMEDGI--IAAVCREVLQALEFL 405 Query: 525 HSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARY 704 HS+ +HRDIK DN L+G+ V + DFG + R+ + GT + Sbjct: 406 HSRHVIHRDIKSDNILLGMD---GSVKLTDFGFCAQLSPEQ-------RKRTTMVGTPYW 455 Query: 705 ASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPW 806 + + + D+ SLG + + + G P+ Sbjct: 456 MAPEVVTRKQYGPKVDVWSLGIMAIEMVEGEPPY 489
>Q6FN53:STE20_CANGA Serine/threonine-protein kinase STE20 - Candida glabrata (Yeast)| (Torulopsis glabrata) Length = 915 Score = 71.6 bits (174), Expect = 1e-11 Identities = 54/216 (25%), Positives = 105/216 (48%), Gaps = 2/216 (0%) Frame = +3 Query: 165 PMEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKT--KHPQLLYESKLYR 338 P +P+ +KYR K+G G+ G +Y+ + ++ + VAIK N++ K +L E + R Sbjct: 613 PGDPK--SKYRDLIKIGQGASGGVYIAHDTESEDSVAIKQMNLEKQPKKELILNEILVMR 670 Query: 339 VLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVE 518 + ++ + + +GD +++ + G SL D+ + C LS + + + + ++ Sbjct: 671 ESKHSNIVNFIDSYLAKGDLWIVMEYMEGGSLTDVVTHC--LLSEGQIGAVCRETLKGLQ 728 Query: 519 FIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTA 698 F+HSK LHRDIK DN L+ L + + DFG + + + + + GT Sbjct: 729 FLHSKGVLHRDIKSDNILLSL---KGNIKLTDFGFCAQINENNL-------KRTTMVGTP 778 Query: 699 RYASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPW 806 + + E + D+ SLG +++ + G P+ Sbjct: 779 YWMAPEVVSRKEYGPKVDIWSLGIMIIEMIEGEPPY 814
>P54744:PKNB_MYCLE Probable serine/threonine-protein kinase pknB - Mycobacterium| leprae Length = 622 Score = 71.6 bits (174), Expect = 1e-11 Identities = 64/270 (23%), Positives = 115/270 (42%), Gaps = 22/270 (8%) Frame = +3 Query: 174 PRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGG 353 P + ++Y LG LG G E++L +++ + +VA+K+ Y + R Q Sbjct: 5 PHLSDRYELGDILGFGGMSEVHLARDIRLHRDVAVKVLRADLARDPSFY-LRFRREAQNA 63 Query: 354 TGISNVKWFGV---------EGDYNVLVMDVL-GPSLEDLFSFCNRKLSLKTVLMLADQM 503 +++ V G +VM+ + G +L D+ + + ++AD Sbjct: 64 AALNHPSIVAVYDTGEAETSAGPLPYIVMEYVDGATLRDIVHTDGPMPPQQAIEIVADAC 123 Query: 504 INRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKN 683 + F H +HRD+KP N ++ N V ++DFG+A+ D+++ + Sbjct: 124 -QALNFSHQNGIIHRDVKPANIMISA---TNAVKVMDFGIARAIADSTS-----VTQTAA 174 Query: 684 LTGTARYASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGT------------ 827 + GTA+Y S G R D+ SLG VL L G P+ G + Sbjct: 175 VIGTAQYLSPEQARGDSVDARSDVYSLGCVLYEILTGEPPFIGDSPVSVAYQHVREDPIP 234 Query: 828 KKQKYEKISERKIATSIEALCRGYPSEFQS 917 Q++E IS A ++AL + + +Q+ Sbjct: 235 PSQRHEGISVDLDAVVLKALAKNPENRYQT 264
>Q9XA16:PKNX_STRCO Probable serine/threonine-protein kinase SCO3848 - Streptomyces| coelicolor Length = 673 Score = 71.2 bits (173), Expect = 1e-11 Identities = 63/223 (28%), Positives = 105/223 (47%), Gaps = 11/223 (4%) Frame = +3 Query: 177 RVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK-LENVKTKHPQLLYESKLYRVLQGG 353 R+G +Y LG LG G E+Y + + +VA+K L + P ++++ R Q Sbjct: 6 RLGGRYELGPVLGRGGMAEVYHAHDTRLGRQVAVKTLRADLARDPS--FQARFRREAQSA 63 Query: 354 TGISN---VKWFGVEGDY--NV----LVMD-VLGPSLEDLFSFCNRKLSLKTVLMLADQM 503 +++ V + DY NV +VM+ V G +L +L RKL + L + + Sbjct: 64 ASLNHPAIVAVYDTGEDYIDNVSIPYIVMEYVDGSTLRELL-HSGRKLLPERTLEMTIGI 122 Query: 504 INRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKN 683 + +E+ H +HRDIKP N ++ R QV ++DFG+A+ D+ + + Sbjct: 123 LQALEYSHRAGIVHRDIKPANVML---TRNGQVKVMDFGIARAMGDSG----MTMTQTAA 175 Query: 684 LTGTARYASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQG 812 + GTA+Y S G + R D+ S G +L L P+ G Sbjct: 176 VIGTAQYLSPEQAKGEQVDARSDLYSTGCLLYELLTVRPPFVG 218
>O14965:STK6_HUMAN Serine/threonine-protein kinase 6 - Homo sapiens (Human)| Length = 403 Score = 70.5 bits (171), Expect = 2e-11 Identities = 75/292 (25%), Positives = 121/292 (41%), Gaps = 9/292 (3%) Frame = +3 Query: 6 PPHNEKEYPQSHTSIPAQTLATNLRNSSLAQVPP*LDALNLGGGSVACVRARPPMEPRVG 185 P N+K+ TS+P ++ L N+ ++ P N +A + + R Sbjct: 70 PVQNQKQKQLQATSVP-HPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKNEESKKRQW 128 Query: 186 --NKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK------LENVKTKHPQLLYESKLYRV 341 + +GR LG G FG +YL Q+ +A+K LE +H QL E ++ Sbjct: 129 ALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEH-QLRREVEIQSH 187 Query: 342 LQGGTGISNVKWF-GVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVE 518 L+ + +F Y +L LG +L K + ++ N + Sbjct: 188 LRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLS--KFDEQRTATYITELANALS 245 Query: 519 FIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTA 698 + HSK +HRDIKP+N L+G A ++ + DFG + H P L GT Sbjct: 246 YCHSKRVIHRDIKPENLLLG---SAGELKIADFGWS---------VHAPSSRRTTLCGTL 293 Query: 699 RYASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKIS 854 Y G + D+ SLG + FL G P++ A T ++ Y++IS Sbjct: 294 DYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFE---ANTYQETYKRIS 342
>P22517:KCC2_YEAST Calcium/calmodulin-dependent protein kinase II - Saccharomyces| cerevisiae (Baker's yeast) Length = 447 Score = 70.5 bits (171), Expect = 2e-11 Identities = 47/155 (30%), Positives = 78/155 (50%), Gaps = 6/155 (3%) Frame = +3 Query: 192 YRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHP-----QLLYES-KLYRVLQGG 353 Y GR LG+GSFG + + TNE+VAIK+ K Q+LYE + + L Sbjct: 47 YIFGRTLGAGSFGVVRQARKLSTNEDVAIKILLKKALQGNNVQLQMLYEELSILQKLSHP 106 Query: 354 TGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSK 533 +S WF + + ++ G L D + + V ++ Q++ VE++HSK Sbjct: 107 NIVSFKDWFESKDKFYIVTQLATGGELFDRILSRGKFTEVDAVEIIV-QILGAVEYMHSK 165 Query: 534 SFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYR 638 + +HRD+KP+N L + + + DFG+AK+ + Sbjct: 166 NVVHRDLKPENVLYVDKSENSPLVIADFGIAKQLK 200
>Q5RJI5:BRSK1_MOUSE BR serine/threonine-protein kinase 1 - Mus musculus (Mouse)| Length = 778 Score = 70.5 bits (171), Expect = 2e-11 Identities = 66/234 (28%), Positives = 103/234 (44%), Gaps = 8/234 (3%) Frame = +3 Query: 129 GGGSVAC----VRARPPMEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLEN-V 293 GGGS A PP + YRL + LG G G + LG + T ++VA+K+ N Sbjct: 9 GGGSPAYHLPHPHPHPPQHAQYVGPYRLEKTLGKGQTGLVKLGVHCITGQKVAVKIVNRE 68 Query: 294 KTKHPQLLYESKLYRVLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRK--L 467 K L+ + +L+ +K V + L + + S +LF + +K L Sbjct: 69 KLSESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRL 128 Query: 468 SLKTVLMLADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTS 647 + K Q+++ ++F HS S HRD+KP+N L+ N + + DFG+A S Sbjct: 129 TPKEARKFFRQIVSALDFCHSYSICHRDLKPENLLL---DEKNNIRIADFGMASLQVGDS 185 Query: 648 THQHIPYRENKNLTGTARYASVSTHLGIE-QSRRDDMESLGYVLMYFLRGSLPW 806 + G+ YA G + RR DM S G +L L G+LP+ Sbjct: 186 LLE--------TSCGSPHYACPEVIKGEKYDGRRADMWSCGVILFALLVGALPF 231
>O14299:WIS4_SCHPO MAP kinase kinase kinase wis4 - Schizosaccharomyces pombe (Fission| yeast) Length = 1401 Score = 70.1 bits (170), Expect = 3e-11 Identities = 63/219 (28%), Positives = 106/219 (48%), Gaps = 13/219 (5%) Frame = +3 Query: 189 KYRLGRKLGSGSFGEIYLGTNVQTNEEVA---IKLENVKTKHPQLLYESKLYRVLQGGTG 359 +++ G + SG FG++Y G N++T + +A IKL++ +T + VL+ Sbjct: 1036 RWQQGHFVRSGMFGDVYTGVNMETGDLLAVKEIKLQDSRTFRSTVDQIHNEMTVLERLNH 1095 Query: 360 ISNVKWFGVEGDYN---VLVMDVLGPSLEDLFSFCNRKLSLKTVLML-ADQMINRVEFIH 527 + V ++GVE + + G SL DL + + ++ + VL + Q++ + +IH Sbjct: 1096 PNVVTYYGVEVHREKVYIFMEFCQGGSLADLLA--HGRIEDENVLKVYVVQLLEGLAYIH 1153 Query: 528 SKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYR----ENKNLTGT 695 S+ LHRDIKP N L+ + DFG A Y T + Y E ++L GT Sbjct: 1154 SQHILHRDIKPANILL---DHRGMIKYSDFGSA-LYVSPPTDPEVRYEDIQPELQHLAGT 1209 Query: 696 ARYASVSTHLGIEQSRRDDME--SLGYVLMYFLRGSLPW 806 Y + LG ++ M+ SLG V++ + GS PW Sbjct: 1210 PMYMAPEIILGTKKGDFGAMDIWSLGCVILEMMTGSTPW 1248
>Q7RJG2:CDPK4_PLAYO Calcium-dependent protein kinase 4 - Plasmodium yoelii yoelii| Length = 528 Score = 69.7 bits (169), Expect = 4e-11 Identities = 61/216 (28%), Positives = 103/216 (47%), Gaps = 8/216 (3%) Frame = +3 Query: 189 KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVK-----TKHPQLLYESKLYRVLQGG 353 +Y+ + LG GSFGE+ L + T E AIK+ + K T LL E +L ++L Sbjct: 69 QYKGIKILGKGSFGEVILSKDKHTGHEYAIKVISKKHVKRKTDKQSLLREVELLKMLDH- 127 Query: 354 TGISNVKWFGVEGDYNVLVMDVL--GPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIH 527 I + F + +Y LV DV G +++ S ++ + Q+++ + ++H Sbjct: 128 INIMKLYEFFEDNNYYYLVSDVYSGGELFDEIIS--RKRFYEVDAARIIKQVLSGITYMH 185 Query: 528 SKSFLHRDIKPDNFLMGLGKRANQVY-MIDFGLAKKYRDTSTHQHIPYRENKNLTGTARY 704 + +HRD+KP+N L+ + + + +IDFGL STH ++ K+ GTA Y Sbjct: 186 KNNVVHRDLKPENILLETKNKEDMIIKIIDFGL-------STHFEYS-KKMKDKIGTAYY 237 Query: 705 ASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQG 812 + G + D+ S G +L L G P+ G Sbjct: 238 IAPDVLHG-TYDEKCDIWSCGVILYILLSGCPPFNG 272
>P62345:CDPK4_PLABA Calcium-dependent protein kinase 4 - Plasmodium berghei (strain| Anka) Length = 528 Score = 69.7 bits (169), Expect = 4e-11 Identities = 61/216 (28%), Positives = 103/216 (47%), Gaps = 8/216 (3%) Frame = +3 Query: 189 KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVK-----TKHPQLLYESKLYRVLQGG 353 +Y+ + LG GSFGE+ L + T E AIK+ + K T LL E +L ++L Sbjct: 69 QYKGIKILGKGSFGEVILSKDKHTGHEYAIKVISKKHVKRKTDKQSLLREVELLKMLDH- 127 Query: 354 TGISNVKWFGVEGDYNVLVMDVL--GPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIH 527 I + F + +Y LV DV G +++ S ++ + Q+++ + ++H Sbjct: 128 INIMKLYEFFEDNNYYYLVSDVYSGGELFDEIIS--RKRFYEVDAARIIKQVLSGITYMH 185 Query: 528 SKSFLHRDIKPDNFLMGLGKRANQVY-MIDFGLAKKYRDTSTHQHIPYRENKNLTGTARY 704 + +HRD+KP+N L+ + + + +IDFGL STH ++ K+ GTA Y Sbjct: 186 KNNVVHRDLKPENILLETKNKEDMIIKIIDFGL-------STHFEYS-KKMKDKIGTAYY 237 Query: 705 ASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQG 812 + G + D+ S G +L L G P+ G Sbjct: 238 IAPDVLHG-TYDEKCDIWSCGVILYILLSGCPPFNG 272
>Q01389:BCK1_YEAST Serine/threonine-protein kinase BCK1/SLK1/SSP31 - Saccharomyces| cerevisiae (Baker's yeast) Length = 1478 Score = 69.7 bits (169), Expect = 4e-11 Identities = 62/222 (27%), Positives = 105/222 (47%), Gaps = 16/222 (7%) Frame = +3 Query: 201 GRKLGSGSFGEIYLGTNVQTNEEVAIKLENV---KTKHPQLLYESKLYR----VLQGGTG 359 G +G GSFG +YL NV T E +A+K V +++ +L + R L+ Sbjct: 1178 GEMIGKGSFGAVYLCLNVTTGEMMAVKQVEVPKYSSQNEAILSTVEALRSEVSTLKDLDH 1237 Query: 360 ISNVKWFGVEGD---YNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHS 530 ++ V++ G E Y++ + V G S+ L R + L Q++ + ++HS Sbjct: 1238 LNIVQYLGFENKNNIYSLFLEYVAGGSVGSLIRMYGR-FDEPLIKHLTTQVLKGLAYLHS 1296 Query: 531 KSFLHRDIKPDNFLM---GLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTAR 701 K LHRD+K DN L+ G+ K + DFG+++K +D ++ + R GT Sbjct: 1297 KGILHRDMKADNLLLDQDGICK------ISDFGISRKSKDIYSNSDMTMR------GTVF 1344 Query: 702 YAS---VSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLK 818 + + V T G S + D+ SLG +++ G PW L+ Sbjct: 1345 WMAPEMVDTKQG--YSAKVDIWSLGCIVLEMFAGKRPWSNLE 1384
>Q90ZY4:SBK1_DANRE Serine/threonine-protein kinase SBK1 - Danio rerio (Zebrafish)| (Brachydanio rerio) Length = 385 Score = 69.3 bits (168), Expect = 5e-11 Identities = 84/367 (22%), Positives = 153/367 (41%), Gaps = 21/367 (5%) Frame = +3 Query: 180 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK-LENVKTKHPQLLYESKLYRVLQGGT 356 V Y + R+LG G++G++ L + ++A+K L+ TK L E + L Sbjct: 28 VNKYYEVIRELGKGTYGKVDLVIHKIRGSKMALKFLKKKSTKLKSFLREYSISLYLSPCP 87 Query: 357 GISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLM--LADQMINRVEFIHS 530 I N+ E D + PS DLF ++ L + Q+ +E++HS Sbjct: 88 FIINMFGIAFETDEYYVFAQEYAPS-GDLFDIIPPQVGLPEPVAKRCVHQVAIALEYLHS 146 Query: 531 KSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYAS 710 K +HRDIKP+N L+ K +V + DFG+ ++ K ++GT Y + Sbjct: 147 KKLVHRDIKPENILI-FDKECRKVKLSDFGMTRRAGSPV----------KRVSGTIPYTA 195 Query: 711 -----VSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQ-GLKAGTKKQKYEKISERKIAT 872 S H G D+ + G +L L G+ PW+ + + T +++ + +R+ Sbjct: 196 PELCDTSKHDGFCVDYSTDVWAFGVLLFCMLTGNFPWEKAMPSDTFYEEFVRWQKRRTG- 254 Query: 873 SIEALCRGYPSEFQSFFHYCRSLRFEDSPDYQYLKRLFRDLFIREGFQFDYVFDWTILKY 1052 ++ + R + E F +L E +K +F L R ++ D T + Sbjct: 255 AVPSQWRRFTDESLRMFRKLLALEQERRCS---VKEVFAHLGHR------WMLDGTSGNH 305 Query: 1053 QQSQMTS-----------VPPRAIAAAAGQSSGMAPIASNNRLSATEEGRISGW-SADPT 1196 QS + S + + ++ A S+ + P ++N+ S + +S S + + Sbjct: 306 HQSVLNSSSEEDELLVDRMKQQTLSPTANTSNAIEPGSANHFTSMSTNSSVSSTNSYERS 365 Query: 1197 RSQVPPT 1217 PPT Sbjct: 366 ARDSPPT 372
>Q9FZ36:M3K2_ARATH Mitogen-activated protein kinase kinase kinase 2 - Arabidopsis| thaliana (Mouse-ear cress) Length = 651 Score = 69.3 bits (168), Expect = 5e-11 Identities = 66/293 (22%), Positives = 129/293 (44%), Gaps = 13/293 (4%) Frame = +3 Query: 15 NEKEYPQSHTSIPAQTLATNLRNSSL---AQVPP*LDALNLGGGSVACVRARPPMEPRVG 185 N++ +P S+ A + + +R S + +Q PP + + V+ +PP+ Sbjct: 22 NQENHPPPFPSLLADKITSCIRKSMVFAKSQSPP----------NNSTVQIKPPI----- 66 Query: 186 NKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK----------LENVKTKHPQLLYESKLY 335 ++R G+ +G G+FG +Y+G N+ + E +A+K E + +L E KL Sbjct: 67 -RWRKGQLIGRGAFGTVYMGMNLDSGELLAVKQVLITSNCASKEKTQAHIQELEEEVKLL 125 Query: 336 RVLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRV 515 + L + + + N+L+ V G S+ L V +Q++ + Sbjct: 126 KNLSHPNIVRYLGTVREDETLNILLEFVPGGSISSLLEKFG-AFPESVVRTYTNQLLLGL 184 Query: 516 EFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGT 695 E++H+ + +HRDIK N L+ + + DFG +K+ + +T K++ GT Sbjct: 185 EYLHNHAIMHRDIKGANILV---DNQGCIKLADFGASKQVAELAT-----ISGAKSMKGT 236 Query: 696 ARYASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKIS 854 + + L S D+ S+G ++ + G PW Q+Y++I+ Sbjct: 237 PYWMAPEVILQTGHSFSADIWSVGCTVIEMVTGKAPW--------SQQYKEIA 281
>Q8IBS5:CDPK4_PLAF7 Calcium-dependent protein kinase 4 - Plasmodium falciparum (isolate| 3D7) Length = 528 Score = 69.3 bits (168), Expect = 5e-11 Identities = 61/216 (28%), Positives = 103/216 (47%), Gaps = 8/216 (3%) Frame = +3 Query: 189 KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVK-----TKHPQLLYESKLYRVLQGG 353 +Y+ + LG GSFGE+ L + T E AIK+ + K T LL E +L ++L Sbjct: 69 QYKGIKILGKGSFGEVILSRDKHTGHEYAIKVISKKHVKRKTDKESLLREVELLKMLDH- 127 Query: 354 TGISNVKWFGVEGDYNVLVMDVL--GPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIH 527 I + F + +Y LV DV G +++ S ++ + Q+++ + ++H Sbjct: 128 INIMKLYEFFEDNNYYYLVSDVYTGGELFDEIIS--RKRFYEIDAARIIKQILSGITYMH 185 Query: 528 SKSFLHRDIKPDNFLMGLGKRANQVY-MIDFGLAKKYRDTSTHQHIPYRENKNLTGTARY 704 + +HRD+KP+N L+ + + + +IDFGL STH ++ K+ GTA Y Sbjct: 186 KNNVVHRDLKPENILLETKNKEDMIIKIIDFGL-------STHFEYS-KKMKDKIGTAYY 237 Query: 705 ASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQG 812 + G + D+ S G +L L G P+ G Sbjct: 238 IAPDVLHG-TYDEKCDIWSCGVILYILLSGCPPFNG 272
>Q2TA06:STK6_BOVIN Serine/threonine-protein kinase 6 - Bos taurus (Bovine)| Length = 402 Score = 68.9 bits (167), Expect = 7e-11 Identities = 63/228 (27%), Positives = 97/228 (42%), Gaps = 7/228 (3%) Frame = +3 Query: 192 YRLGRKLGSGSFGEIYLGTNVQTNEEVAIK------LENVKTKHPQLLYESKLYRVLQGG 353 + +GR LG G FG +YL Q+ +A+K LE +H QL E ++ L+ Sbjct: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEH-QLRREVEIQSHLRHP 191 Query: 354 TGISNVKWF-GVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHS 530 + +F Y +L LG +L K + ++ N + + HS Sbjct: 192 NILRLYGYFHDATRVYLILEYAPLGAVYRELQKLS--KFDEQRTATYITELANALSYCHS 249 Query: 531 KSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYAS 710 K +HRDIKP+N L+G A ++ + DFG + H P L GT Y Sbjct: 250 KRVIHRDIKPENLLLG---SAGELKIADFGWS---------VHAPSSRRTTLCGTLDYLP 297 Query: 711 VSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKIS 854 G + D+ SLG + FL G P++ A T ++ Y +IS Sbjct: 298 PEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFE---ADTYQETYRRIS 342
>Q9YHZ5:PIM1_DANRE Serine/threonine-protein kinase Pim-1 - Danio rerio (Zebrafish)| (Brachydanio rerio) Length = 310 Score = 68.9 bits (167), Expect = 7e-11 Identities = 53/171 (30%), Positives = 82/171 (47%), Gaps = 19/171 (11%) Frame = +3 Query: 189 KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK---LENVK--TKHP----QLLYESKLYRV 341 +Y +G LGSG FG +Y G + ++VAIK + ++ +K P + E L + Sbjct: 29 QYTMGNLLGSGGFGSVYSGHRISDGQKVAIKQISRDRIQQWSKMPGEVNPVPNEIALLQS 88 Query: 342 LQGGTG--------ISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVL--ML 491 L GG+G I + WF + G ++V + +DLF F + L L Sbjct: 89 LGGGSGSVPGHRGIIRMLDWFEIPGQEYLIVFE-KPQHCQDLFDFITERGRLDESLARRF 147 Query: 492 ADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDT 644 Q+I V+F HSK +HRDIK +N L + R + +IDFG +D+ Sbjct: 148 LKQVIEAVQFCHSKGIVHRDIKDENIL--VDTRTGDIKVIDFGSGATLKDS 196
>Q5XIS9:KPCD2_RAT Serine/threonine-protein kinase D2 - Rattus norvegicus (Rat)| Length = 875 Score = 68.9 bits (167), Expect = 7e-11 Identities = 58/205 (28%), Positives = 99/205 (48%), Gaps = 6/205 (2%) Frame = +3 Query: 210 LGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHP-----QLLYESKLYRVLQGGTGISNVK 374 LGSG FG +Y G + +T +VA+K+ + K + P QL E + + L+ GI N++ Sbjct: 558 LGSGQFGVVYGGKHRKTGRDVAVKVID-KLRFPTKQESQLRNEVAILQSLRH-PGIVNLE 615 Query: 375 WFGVEGDYNVLVMDVL-GPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFLHRD 551 + +VM+ L G LE + S +L + L Q++ + +H K+ +H D Sbjct: 616 CMFETPEKVFVVMEKLHGDMLEMILSSEKGRLPERLTKFLITQILVALRHLHFKNIVHCD 675 Query: 552 IKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVSTHLGI 731 +KP+N L+ QV + DFG A+ + S +++ GT Y + L Sbjct: 676 LKPENVLLASADPFPQVKLCDFGFARIIGEKSF--------RRSVVGTPAYLAPEVLLNQ 727 Query: 732 EQSRRDDMESLGYVLMYFLRGSLPW 806 +R DM S+G ++ L G+ P+ Sbjct: 728 GYNRSLDMWSVGVIMYVSLSGTFPF 752
>Q8BZ03:KPCD2_MOUSE Serine/threonine-protein kinase D2 - Mus musculus (Mouse)| Length = 875 Score = 68.9 bits (167), Expect = 7e-11 Identities = 58/205 (28%), Positives = 99/205 (48%), Gaps = 6/205 (2%) Frame = +3 Query: 210 LGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHP-----QLLYESKLYRVLQGGTGISNVK 374 LGSG FG +Y G + +T +VA+K+ + K + P QL E + + L+ GI N++ Sbjct: 558 LGSGQFGVVYGGKHRKTGRDVAVKVID-KLRFPTKQESQLRNEVAILQSLRH-PGIVNLE 615 Query: 375 WFGVEGDYNVLVMDVL-GPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFLHRD 551 + +VM+ L G LE + S +L + L Q++ + +H K+ +H D Sbjct: 616 CMFETPEKVFVVMEKLHGDMLEMILSSEKGRLPERLTKFLITQILVALRHLHFKNIVHCD 675 Query: 552 IKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVSTHLGI 731 +KP+N L+ QV + DFG A+ + S +++ GT Y + L Sbjct: 676 LKPENVLLASADPFPQVKLCDFGFARIIGEKSF--------RRSVVGTPAYLAPEVLLNQ 727 Query: 732 EQSRRDDMESLGYVLMYFLRGSLPW 806 +R DM S+G ++ L G+ P+ Sbjct: 728 GYNRSLDMWSVGVIMYVSLSGTFPF 752
>Q9BZL6:KPCD2_HUMAN Serine/threonine-protein kinase D2 - Homo sapiens (Human)| Length = 878 Score = 68.9 bits (167), Expect = 7e-11 Identities = 58/205 (28%), Positives = 99/205 (48%), Gaps = 6/205 (2%) Frame = +3 Query: 210 LGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHP-----QLLYESKLYRVLQGGTGISNVK 374 LGSG FG +Y G + +T +VA+K+ + K + P QL E + + L+ GI N++ Sbjct: 557 LGSGQFGVVYGGKHRKTGRDVAVKVID-KLRFPTKQESQLRNEVAILQSLRH-PGIVNLE 614 Query: 375 WFGVEGDYNVLVMDVL-GPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFLHRD 551 + +VM+ L G LE + S +L + L Q++ + +H K+ +H D Sbjct: 615 CMFETPEKVFVVMEKLHGDMLEMILSSEKGRLPERLTKFLITQILVALRHLHFKNIVHCD 674 Query: 552 IKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVSTHLGI 731 +KP+N L+ QV + DFG A+ + S +++ GT Y + L Sbjct: 675 LKPENVLLASADPFPQVKLCDFGFARIIGEKSF--------RRSVVGTPAYLAPEVLLNQ 726 Query: 732 EQSRRDDMESLGYVLMYFLRGSLPW 806 +R DM S+G ++ L G+ P+ Sbjct: 727 GYNRSLDMWSVGVIMYVSLSGTFPF 751
>Q12236:KOK0_YEAST Probable serine/threonine-protein kinase YOL100W - Saccharomyces| cerevisiae (Baker's yeast) Length = 1081 Score = 68.9 bits (167), Expect = 7e-11 Identities = 98/454 (21%), Positives = 176/454 (38%), Gaps = 37/454 (8%) Frame = +3 Query: 192 YRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVK--TKHPQLLYESKLYRVLQG-GTGI 362 ++ G +G G++ + L T++ T + A K+ N + + ++ Y S LQ Sbjct: 179 FKFGSVIGDGAYSTVMLATSIDTKKRYAAKVLNKEYLIRQKKVKYVSIEKTALQKLNNSP 238 Query: 363 SNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLM--LADQMINRVEFIHSKS 536 S V+ F D + L + D S + SL A Q+I+ ++++HS Sbjct: 239 SVVRLFSTFQDESSLYFLLEYAPNGDFLSLMKKYGSLDETCARYYAAQIIDAIDYLHSNG 298 Query: 537 FLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRE----NKNLTGTARY 704 +HRDIKP+N L+ ++ + DFG AK T+ P + +K+ GTA Y Sbjct: 299 IIHRDIKPENILL---DGEMKIKLTDFGTAKLLNPTNNSVSKPEYDLSTRSKSFVGTAEY 355 Query: 705 ASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKISERKIATSIEA 884 S R D+ + G +L + G P+ K E ++ +K+ A Sbjct: 356 VSPELLNDSFTDYRCDIWAFGCILFQMIAGKPPF--------KATNEYLTFQKVMKVQYA 407 Query: 885 LCRGYPSEFQSFFHYCRSLRFEDSPDYQYLK--RLFRDLFIREGFQFD----YVFDWTIL 1046 G+P + + +K F+DL ++G + + + I Sbjct: 408 FTPGFPLIIRDLVKKILVKNLDRRLTISQIKEHHFFKDLNFKDGSVWSKTPPEIKPYKIN 467 Query: 1047 KYQQSQMTSVPPRAIAAAAGQSSGMAPIAS------------------NNRLSATEEGRI 1172 M S R + + + G + + + NN A+ E I Sbjct: 468 AKSMQAMPSGSDRKLVKKSVNTLGKSHLVTQRSASSPSVEETTHSTLYNNNTHASTESEI 527 Query: 1173 SGWSADPTRSQVPPTGINA--GSLSKQKSPVRPDLSAPKEAVLSSSTFLGRSGVFSRRPA 1346 S PT + NA G +++ P + S A L++S L + Sbjct: 528 S-IKKRPTDERTAQILENARKGINNRKNQPGKRTPSGAASAALAASAALTK--------- 577 Query: 1347 VSSSRDLPSSEAEPSRSRAPDVS--PGTFQRNSA 1442 + + P+S ++ SRS +P + PGT++R S+ Sbjct: 578 -KTMQSYPTSSSKSSRSSSPATTSRPGTYKRTSS 610
>P0A5S4:PKNB_MYCTU Probable serine/threonine-protein kinase pknB - Mycobacterium| tuberculosis Length = 626 Score = 68.6 bits (166), Expect = 9e-11 Identities = 55/221 (24%), Positives = 95/221 (42%), Gaps = 10/221 (4%) Frame = +3 Query: 180 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTG 359 + ++Y LG LG G E++L +++ + +VA+K+ Y + R Q Sbjct: 7 LSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFY-LRFRREAQNAAA 65 Query: 360 ISNVKWFGV---------EGDYNVLVMDVL-GPSLEDLFSFCNRKLSLKTVLMLADQMIN 509 +++ V G +VM+ + G +L D+ + + ++AD Sbjct: 66 LNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIADAC-Q 124 Query: 510 RVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLT 689 + F H +HRD+KP N ++ N V ++DFG+A+ D+ + + Sbjct: 125 ALNFSHQNGIIHRDVKPANIMISA---TNAVKVMDFGIARAIADSGNS----VTQTAAVI 177 Query: 690 GTARYASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQG 812 GTA+Y S G R D+ SLG VL L G P+ G Sbjct: 178 GTAQYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTG 218
>P0A5S5:PKNB_MYCBO Probable serine/threonine-protein kinase pknB - Mycobacterium bovis| Length = 626 Score = 68.6 bits (166), Expect = 9e-11 Identities = 55/221 (24%), Positives = 95/221 (42%), Gaps = 10/221 (4%) Frame = +3 Query: 180 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTG 359 + ++Y LG LG G E++L +++ + +VA+K+ Y + R Q Sbjct: 7 LSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFY-LRFRREAQNAAA 65 Query: 360 ISNVKWFGV---------EGDYNVLVMDVL-GPSLEDLFSFCNRKLSLKTVLMLADQMIN 509 +++ V G +VM+ + G +L D+ + + ++AD Sbjct: 66 LNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIADAC-Q 124 Query: 510 RVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLT 689 + F H +HRD+KP N ++ N V ++DFG+A+ D+ + + Sbjct: 125 ALNFSHQNGIIHRDVKPANIMISA---TNAVKVMDFGIARAIADSGNS----VTQTAAVI 177 Query: 690 GTARYASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQG 812 GTA+Y S G R D+ SLG VL L G P+ G Sbjct: 178 GTAQYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTG 218
>Q75DK7:STE20_ASHGO Serine/threonine-protein kinase STE20 - Ashbya gossypii (Yeast)| (Eremothecium gossypii) Length = 971 Score = 68.2 bits (165), Expect = 1e-10 Identities = 52/208 (25%), Positives = 101/208 (48%), Gaps = 3/208 (1%) Frame = +3 Query: 192 YRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTGISNV 371 YR K+G G+ G +Y + TN VAIK N++ + + L +++ V++G + V Sbjct: 683 YRNLVKIGQGASGGVYTAYEIGTNASVAIKQMNLEKQPKKELIINEIL-VMKGSRHNNIV 741 Query: 372 KWFG---VEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFL 542 + ++GD V++ + G SL D+ + C L+ + ++ + + + F+HSK + Sbjct: 742 NFIDSYLLKGDLWVIMEYMEGGSLTDVVTHCI--LTEGQIAAVSRETLRGLHFLHSKGVI 799 Query: 543 HRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVSTH 722 HRDIK DN L+ + + + DFG + +T+ + + GT + + Sbjct: 800 HRDIKSDNILLSMD---GNIKLTDFGFCAQINETNL-------KRTTMVGTPYWMAPEVV 849 Query: 723 LGIEQSRRDDMESLGYVLMYFLRGSLPW 806 E + D+ SLG +++ + G P+ Sbjct: 850 SRKEYGPKVDIWSLGIMIIEMIEGEPPY 877
>O00311:CDC7_HUMAN Cell division cycle 7-related protein kinase - Homo sapiens (Human)| Length = 574 Score = 68.2 bits (165), Expect = 1e-10 Identities = 48/161 (29%), Positives = 79/161 (49%), Gaps = 4/161 (2%) Frame = +3 Query: 174 PRVGNKYRLGRKLGSGSFGEIYLGT---NVQTNEEVAIKLENVKTKHP-QLLYESKLYRV 341 P++ N +++ K+G G+F +YL T V E++A+K + T HP ++ E + V Sbjct: 52 PQLSNVFKIEDKIGEGTFSSVYLATAQLQVGPEEKIALK-HLIPTSHPIRIAAELQCLTV 110 Query: 342 LQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEF 521 G + VK+ + D+ V+ M L E N LS + V + ++ Sbjct: 111 AGGQDNVMGVKYCFRKNDHVVIAMPYL--EHESFLDILN-SLSFQEVREYMLNLFKALKR 167 Query: 522 IHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDT 644 IH +HRD+KP NFL +R + ++DFGLA+ DT Sbjct: 168 IHQFGIVHRDVKPSNFL--YNRRLKKYALVDFGLAQGTHDT 206
>Q8TDC3:BRSK1_HUMAN BR serine/threonine-protein kinase 1 - Homo sapiens (Human)| Length = 794 Score = 68.2 bits (165), Expect = 1e-10 Identities = 69/240 (28%), Positives = 105/240 (43%), Gaps = 4/240 (1%) Frame = +3 Query: 99 VPP*LDALNLGGGSVACVRARPPMEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAI 278 VP D + GGG R VG YRL + LG G G + LG + T ++VAI Sbjct: 20 VPERKDEVAGGGGEEEEAEERGRHAQYVG-PYRLEKTLGKGQTGLVKLGVHCITGQKVAI 78 Query: 279 KLEN-VKTKHPQLLYESKLYRVLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFC 455 K+ N K L+ + +L+ +K V + L + + S +LF + Sbjct: 79 KIVNREKLSESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYL 138 Query: 456 NRK--LSLKTVLMLADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAK 629 +K L+ K Q+++ ++F HS S HRD+KP+N L+ N + + DFG+A Sbjct: 139 VKKGRLTPKEARKFFRQIVSALDFCHSYSICHRDLKPENLLL---DEKNNIRIADFGMAS 195 Query: 630 KYRDTSTHQHIPYRENKNLTGTARYASVSTHLGIE-QSRRDDMESLGYVLMYFLRGSLPW 806 S + G+ YA G + RR DM S G +L L G+LP+ Sbjct: 196 LQVGDSLLE--------TSCGSPHYACPEVIKGEKYDGRRADMWSCGVILFALLVGALPF 247
>P26794:PIM1_RAT Proto-oncogene serine/threonine-protein kinase Pim-1 - Rattus| norvegicus (Rat) Length = 313 Score = 67.8 bits (164), Expect = 2e-10 Identities = 78/300 (26%), Positives = 130/300 (43%), Gaps = 15/300 (5%) Frame = +3 Query: 123 NLGGGSVACVRARPPMEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK------- 281 +L +A + + P+E ++Y++G LGSG FG +Y G V N VAIK Sbjct: 19 DLHANKLAPGKEKEPLE----SQYQVGPLLGSGGFGSVYSGIRVADNLPVAIKHVEKDRI 74 Query: 282 -----LENVKTKHPQLLYESKLYRVLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLF 446 L N T+ P + L +V G +G+ + + D VL+++ P ++DLF Sbjct: 75 SDWGELPN-GTRVPMEVV--LLKKVSSGFSGVIRLLDWFERPDSFVLILERPEP-VQDLF 130 Query: 447 SFCNRKLSLKTVLMLAD--QMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFG 620 F + +L+ L + Q++ V H+ LHRDIK +N L+ L + ++ +IDFG Sbjct: 131 DFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNR--GELKLIDFG 188 Query: 621 LAKKYRDTSTHQHIPYRENKNLTGTARYASVS-THLGIEQSRRDDMESLGYVLMYFLRGS 797 +DT + GT Y+ R + SLG +L + G Sbjct: 189 SGALLKDT---------VYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGD 239 Query: 798 LPWQGLKAGTKKQKYEKISERKIATSIEALCRGYPSEFQSFFHYCRSLRFEDSPDYQYLK 977 +P++ + K Q Y + + SE Q +C SLR D P ++ ++ Sbjct: 240 IPFEHDEEIVKGQVYFR--------------QRVSSECQHLIRWCLSLRPSDRPSFEEIQ 285
>Q03497:STE20_YEAST Serine/threonine-protein kinase STE20 - Saccharomyces cerevisiae| (Baker's yeast) Length = 939 Score = 67.0 bits (162), Expect = 3e-10 Identities = 53/209 (25%), Positives = 102/209 (48%), Gaps = 3/209 (1%) Frame = +3 Query: 189 KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTGISN 368 KY K+G G+ G +Y + TN VAIK N++ + + L +++ V++G + Sbjct: 619 KYANLVKIGQGASGGVYTAYEIGTNVSVAIKQMNLEKQPKKELIINEIL-VMKGSKHPNI 677 Query: 369 VKW---FGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSF 539 V + + ++GD V++ + G SL D+ + C L+ + + + ++ +EF+HSK Sbjct: 678 VNFIDSYVLKGDLWVIMEYMEGGSLTDVVTHCI--LTEGQIGAVCRETLSGLEFLHSKGV 735 Query: 540 LHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVST 719 LHRDIK DN L+ + + + DFG + + + + + GT + + Sbjct: 736 LHRDIKSDNILLSM---EGDIKLTDFGFCAQINELNL-------KRTTMVGTPYWMAPEV 785 Query: 720 HLGIEQSRRDDMESLGYVLMYFLRGSLPW 806 E + D+ SLG +++ + G P+ Sbjct: 786 VSRKEYGPKVDIWSLGIMIIEMIEGEPPY 814
>Q822K5:PKND_CHLCV Serine/threonine-protein kinase pknD - Chlamydophila caviae| Length = 930 Score = 67.0 bits (162), Expect = 3e-10 Identities = 69/251 (27%), Positives = 117/251 (46%), Gaps = 27/251 (10%) Frame = +3 Query: 189 KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK-----LENVKTKHPQLLYESKLYRVLQGG 353 +Y + R +G G GE+YL + + +VA+K L + + + L E+K+ L Sbjct: 3 RYDIIRMIGKGGMGEVYLAYDPVCSRKVALKRIREDLSDNELLKKRFLREAKIAADLVH- 61 Query: 354 TGISNVKWFGVEGDYNVLVMDVL-GPSLEDLFSF---CN-------RKLSLKTVLMLADQ 500 G+ V + D M + G +L+ L C+ + S+ T L + + Sbjct: 62 PGVVPVFTICSDSDPVYYTMPYIEGYTLKSLLKSVWQCDSLPKDLAEQTSVATFLSIFHK 121 Query: 501 MINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFG--LAKKYRD---TSTHQHIP 665 + + VE++HS+ LHRD+KPDN L+GL ++V ++D+G L+K+ + + IP Sbjct: 122 ICSTVEYVHSRGILHRDLKPDNILLGL---FSEVVILDWGAALSKEMEEDFLSDIDVRIP 178 Query: 666 YRENKNLT------GTARYASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGT 827 N+T GT Y + G S D+ +LG +L L S P+ Sbjct: 179 GSLFSNMTIPGKIVGTPDYMAPERLRGTPASESTDIYALGVILYQMLTLSFPY------- 231 Query: 828 KKQKYEKISER 860 +K+K +KIS R Sbjct: 232 RKKKGQKISLR 242
>Q6CWQ4:IPL1_KLULA Spindle assembly checkpoint kinase - Kluyveromyces lactis (Yeast)| (Candida sphaerica) Length = 361 Score = 67.0 bits (162), Expect = 3e-10 Identities = 61/225 (27%), Positives = 102/225 (45%), Gaps = 5/225 (2%) Frame = +3 Query: 192 YRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRV--LQGGTGIS 365 + +G+ LG G FG++Y + +T A+K K + Q + + R +QG Sbjct: 100 FEIGKILGKGKFGKVYCVKHRETGLICALKAME-KKEIVQYTIQKQFRREVEIQGSFKHK 158 Query: 366 NV-KWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLM--LADQMINRVEFIHSKS 536 N+ + +G D + + + +L+ F L L QM N ++++HSK+ Sbjct: 159 NLTQLYGFFYDEKRVYLLMEYVYYGELYKFLKNNGPLNETLASYFVYQMANALDYMHSKN 218 Query: 537 FLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVS 716 LHRDIKP+N L+G N + + DFG + D ++ K L GT Y S Sbjct: 219 ILHRDIKPENILIGFN---NTIKLTDFGWSVYNEDG--------QKRKTLCGTIDYLSPE 267 Query: 717 THLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKI 851 E + + D+ +LG + L GS P++ TK+ Y +I Sbjct: 268 LIKSREYNNKVDVWALGVLTYELLVGSPPFE---EDTKEMTYRRI 309
>P38692:KIC1_YEAST Serine/threonine-protein kinase KIC1 - Saccharomyces cerevisiae| (Baker's yeast) Length = 1080 Score = 66.6 bits (161), Expect = 3e-10 Identities = 89/382 (23%), Positives = 163/382 (42%), Gaps = 21/382 (5%) Frame = +3 Query: 171 EPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQG 350 E V + ++ +G G FG +Y G NV+T AIK+ N+ + ++ + + L Sbjct: 16 EMDVSSLFKRTEVIGRGKFGVVYKGYNVKTGRVYAIKVLNLDSDSDEVEDVQREIQFLAS 75 Query: 351 GTGISNV-KWFG---VEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVE 518 ISN+ +++G + +++ G SL L K+ K + ++ +++ ++ Sbjct: 76 LKQISNITRYYGSYLKDTSLWIIMEHCAGGSLRSLLR--PGKIDEKYIGVIMRELLVALK 133 Query: 519 FIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTA 698 IH + +HRDIK N L+ V + DFG+A + TS + + + GT Sbjct: 134 CIHKDNVIHRDIKAANVLI---TNEGNVKLCDFGVAAQVNQTSLRR-------QTMAGTP 183 Query: 699 RYASVSTHL-GIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTK-----KQKYEKISER 860 + + + G+ + D+ SLG G+ P+ ++A K K ++ +R Sbjct: 184 YWMAPEVIMEGVYYDTKVDIWSLGITTYEIATGNPPYCDVEALRAMQLIIKSKPPRLEDR 243 Query: 861 KIATSIE---ALCRGY-PSEFQSFFHYCRS--LRFEDSPDYQYLKRLF-RDLFIREGFQF 1019 +TS++ ALC P E S +S +R + LK L R L R+ + Sbjct: 244 SYSTSLKEFIALCLDEDPKERLSADDLLKSKFIRAHKATPTSILKELISRYLLFRDKNKN 303 Query: 1020 DYVFDWTILKYQQSQMTSVPPRAIAAAAGQSSGMAPIASN-NRLSATEEGRIS-GWSADP 1193 Y + +I + + S+ + P + G IASN N + EG + W D Sbjct: 304 KYKIEGSIPENEPSKPSEAPKP--SQNGGGDEAQKSIASNDNEIKRVNEGDVEMKWDFDS 361 Query: 1194 TRSQ--VPPTGINAGSLSKQKS 1253 S + IN +L++ + Sbjct: 362 LSSSDYIIENNINLDALAEDNN 383
>P29620:KC47_ORYSJ CDC2+/CDC28-related protein kinase R2 - Oryza sativa subsp.| japonica (Rice) Length = 424 Score = 66.6 bits (161), Expect = 3e-10 Identities = 58/187 (31%), Positives = 87/187 (46%), Gaps = 9/187 (4%) Frame = +3 Query: 177 RVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENV-KTKHP---QLLYESKLYRVL 344 RV ++Y LG G++G ++ + +T VAIK + K K L E KL + L Sbjct: 14 RVADRYLKREVLGEGTYGVVFKAVDTKTGNTVAIKKIRLGKYKEGVNFTALREIKLLKEL 73 Query: 345 QGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFI 524 + I + F +G+ + LV + + LE + N LS M+ + F Sbjct: 74 KDSNIIELIDAFPYKGNLH-LVFEFMETDLEAVIRDRNIVLSPADTKSYIQMMLKGLAFC 132 Query: 525 HSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTS---THQHIP--YRENKNLT 689 H K LHRD+KP+N L+G Q+ + DFGLA+ + THQ YR + L Sbjct: 133 HKKWVLHRDMKPNNLLIGAD---GQLKLADFGLARIFGSPERNFTHQVFARWYRAPELLF 189 Query: 690 GTARYAS 710 GT +Y S Sbjct: 190 GTKQYGS 196
>P18334:CSK2A_CAEEL Casein kinase II subunit alpha - Caenorhabditis elegans| Length = 360 Score = 66.2 bits (160), Expect = 4e-10 Identities = 59/207 (28%), Positives = 101/207 (48%), Gaps = 12/207 (5%) Frame = +3 Query: 192 YRLGRKLGSGSFGEIYLGTNVQTNEEVAIK-LENVKTKHPQLLYESKLYRVLQGGTGISN 368 Y+L RKLG G + E++ G + T+E+V +K L+ VK K ++ E K+ L+GGT I Sbjct: 38 YQLVRKLGRGKYSEVFEGFKMSTDEKVVVKILKPVKKK--KIKREIKILENLRGGTNIIT 95 Query: 369 VKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLAD--------QMINRVEFI 524 + +V D + + +F N + L+D +++ ++F Sbjct: 96 LL---------DVVKDPISRTPALIFEHVNNSDFKQLYQTLSDYDIRYYLYELLKALDFC 146 Query: 525 HSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARY 704 HS+ +HRD+KP N ++ KR ++ +ID+GLA+ Y R++ N+ +RY Sbjct: 147 HSQGIMHRDVKPHNVMIDAEKR--ELRLIDWGLAEFYHP---------RQDYNVRVASRY 195 Query: 705 ASVSTHLGIEQSRRD---DMESLGYVL 776 L ++ D DM SLG +L Sbjct: 196 FK-GPELLVDYQCYDYSLDMWSLGCML 221
>O08678:MARK1_RAT Serine/threonine-protein kinase MARK1 - Rattus norvegicus (Rat)| Length = 793 Score = 65.9 bits (159), Expect = 6e-10 Identities = 65/278 (23%), Positives = 128/278 (46%), Gaps = 9/278 (3%) Frame = +3 Query: 6 PPHNEKEYPQSHTSIPA--QTLATNLRNSSLAQVPP*LDALNLGGGSVACVRARPPMEPR 179 P NE++ ++HTS+ +T ++SS +P +++ + +P Sbjct: 8 PTVNERD-TENHTSVDGYTETHIPPTKSSSRQNIPRCRNSIT----------SATDEQPH 56 Query: 180 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHP----QLLYESKLYRVLQ 347 +GN YRL + +G G+F ++ L +V T EVA+K+ + +P +L E ++ ++L Sbjct: 57 IGN-YRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKILN 115 Query: 348 GGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSF--CNRKLSLKTVLMLADQMINRVEF 521 + VK F V L + + S ++F + + ++ K Q+++ V++ Sbjct: 116 HP---NIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQY 172 Query: 522 IHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTAR 701 H K +HRD+K +N L+ + + DFG + ++ + + G+ Sbjct: 173 CHQKCIVHRDLKAENLLLDADM---NIKIADFGFSNEFTVGN--------KLDTFCGSPP 221 Query: 702 YASVSTHLGIEQSRRD-DMESLGYVLMYFLRGSLPWQG 812 YA+ G + + D+ SLG +L + GSLP+ G Sbjct: 222 YAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDG 259
>Q8VHJ5:MARK1_MOUSE Serine/threonine-protein kinase MARK1 - Mus musculus (Mouse)| Length = 795 Score = 65.9 bits (159), Expect = 6e-10 Identities = 65/278 (23%), Positives = 128/278 (46%), Gaps = 9/278 (3%) Frame = +3 Query: 6 PPHNEKEYPQSHTSIPA--QTLATNLRNSSLAQVPP*LDALNLGGGSVACVRARPPMEPR 179 P NE++ ++HTS+ +T ++SS +P +++ + +P Sbjct: 8 PTVNERD-TENHTSVDGYTETHIPPTKSSSRQNIPRCRNSIT----------SATDEQPH 56 Query: 180 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHP----QLLYESKLYRVLQ 347 +GN YRL + +G G+F ++ L +V T EVA+K+ + +P +L E ++ ++L Sbjct: 57 IGN-YRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKILN 115 Query: 348 GGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSF--CNRKLSLKTVLMLADQMINRVEF 521 + VK F V L + + S ++F + + ++ K Q+++ V++ Sbjct: 116 HP---NIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQY 172 Query: 522 IHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTAR 701 H K +HRD+K +N L+ + + DFG + ++ + + G+ Sbjct: 173 CHQKCIVHRDLKAENLLLDADM---NIKIADFGFSNEFTVGN--------KLDTFCGSPP 221 Query: 702 YASVSTHLGIEQSRRD-DMESLGYVLMYFLRGSLPWQG 812 YA+ G + + D+ SLG +L + GSLP+ G Sbjct: 222 YAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDG 259
>O94806:KPCD3_HUMAN Serine/threonine-protein kinase D3 - Homo sapiens (Human)| Length = 890 Score = 65.9 bits (159), Expect = 6e-10 Identities = 57/205 (27%), Positives = 98/205 (47%), Gaps = 6/205 (2%) Frame = +3 Query: 210 LGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHP-----QLLYESKLYRVLQGGTGISNVK 374 LGSG FG +Y G + +T +VAIK+ + K + P QL E + + L GI N++ Sbjct: 582 LGSGQFGIVYGGKHRKTGRDVAIKVID-KMRFPTKQESQLRNEVAILQNLHH-PGIVNLE 639 Query: 375 WFGVEGDYNVLVMDVL-GPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFLHRD 551 + +VM+ L G LE + S +L + + Q++ + +H K+ +H D Sbjct: 640 CMFETPERVFVVMEKLHGDMLEMILSSEKSRLPERITKFMVTQILVALRNLHFKNIVHCD 699 Query: 552 IKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVSTHLGI 731 +KP+N L+ + QV + DFG A+ + S +++ GT Y + Sbjct: 700 LKPENVLLASAEPFPQVKLCDFGFARIIGEKSF--------RRSVVGTPAYLAPEVLRSK 751 Query: 732 EQSRRDDMESLGYVLMYFLRGSLPW 806 +R DM S+G ++ L G+ P+ Sbjct: 752 GYNRSLDMWSVGVIIYVSLSGTFPF 776
>Q02720:CSK2A_DICDI Casein kinase II subunit alpha - Dictyostelium discoideum (Slime| mold) Length = 337 Score = 65.9 bits (159), Expect = 6e-10 Identities = 45/150 (30%), Positives = 81/150 (54%), Gaps = 2/150 (1%) Frame = +3 Query: 192 YRLGRKLGSGSFGEIYLGTNVQTNEEVAIK-LENVKTKHPQLLYESKLYRVLQGGTGISN 368 Y + RK+G G + E++ G N++ NE+ IK L+ VK K ++ E K+ + L GG I Sbjct: 47 YEIIRKIGRGKYSEVFEGANIKNNEKCVIKVLKPVKKK--KIKREIKILQNLCGGPNI-- 102 Query: 369 VKWFGVEGDYNVLVMDVLGPSLEDL-FSFCNRKLSLKTVLMLADQMINRVEFIHSKSFLH 545 + + V D ++ + + F + L+ V ++++ ++F HS +H Sbjct: 103 ITLYDVVRDPQSKTPSLIFEYINNTDFKHLSPTLTDFDVRYYIRELLHALDFCHSNGIMH 162 Query: 546 RDIKPDNFLMGLGKRANQVYMIDFGLAKKY 635 RD+KP N ++ KR ++Y+ID+GLA+ Y Sbjct: 163 RDVKPSNVMIDHQKR--KLYLIDWGLAEFY 190
>P59241:STK6_RAT Serine/threonine-protein kinase 6 - Rattus norvegicus (Rat)| Length = 397 Score = 65.5 bits (158), Expect = 8e-10 Identities = 62/228 (27%), Positives = 96/228 (42%), Gaps = 7/228 (3%) Frame = +3 Query: 192 YRLGRKLGSGSFGEIYLGTNVQTNEEVAIK------LENVKTKHPQLLYESKLYRVLQGG 353 + +GR LG G FG +YL Q+ +A+K LE +H QL E ++ L+ Sbjct: 126 FDIGRPLGKGKFGNVYLAREKQSKFILALKVLFKVQLEKAGVEH-QLRREVEIQSHLRHP 184 Query: 354 TGISNVKWF-GVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHS 530 + +F Y +L LG +L K + ++ N + + HS Sbjct: 185 NILRLYGYFHDATRVYLILEYAPLGTVYRELQKLS--KFDEQRTATYITELANALSYCHS 242 Query: 531 KSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYAS 710 K +HRDIKP+N L+G ++ + DFG + H P L GT Y Sbjct: 243 KRVIHRDIKPENLLLGSN---GELKIADFGWS---------VHAPSSRRTTLCGTLDYQP 290 Query: 711 VSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKIS 854 G + D+ SLG + FL G P++ A T ++ Y +IS Sbjct: 291 PEMIEGRMHDEKVDLWSLGVLCYEFLVGMPPFE---AHTYQETYRRIS 335
>P97477:STK6_MOUSE Serine/threonine-protein kinase 6 - Mus musculus (Mouse)| Length = 395 Score = 65.5 bits (158), Expect = 8e-10 Identities = 60/228 (26%), Positives = 101/228 (44%), Gaps = 7/228 (3%) Frame = +3 Query: 192 YRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTGISN- 368 + +GR LG G FG +YL Q+ +A+K+ KT+ + E +L R ++ + + + Sbjct: 124 FDIGRPLGKGKFGNVYLARERQSKFILALKVL-FKTQLEKANVEHQLRREVEIQSHLRHP 182 Query: 369 --VKWFGVEGD----YNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHS 530 ++ +G D Y +L LG +L K + ++ N + + HS Sbjct: 183 NILRLYGYFHDATRVYLILEYAPLGTVYRELQKLS--KFDEQRTATYITELANALSYCHS 240 Query: 531 KSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYAS 710 K +HRDIKP+N L+G ++ + DFG + H P + GT Y Sbjct: 241 KRVIHRDIKPENLLLGSN---GELKIADFGWS---------VHAPSSRRTTMCGTLDYLP 288 Query: 711 VSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKIS 854 G + D+ SLG + FL G P++ A T ++ Y +IS Sbjct: 289 PEMIEGRMHDEKVDLWSLGVLCYEFLVGMPPFE---AHTYQETYRRIS 333
>Q8VHF0:MARK3_RAT MAP/microtubule affinity-regulating kinase 3 - Rattus norvegicus| (Rat) Length = 797 Score = 65.5 bits (158), Expect = 8e-10 Identities = 56/221 (25%), Positives = 105/221 (47%), Gaps = 7/221 (3%) Frame = +3 Query: 171 EPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHP----QLLYESKLYR 338 +P +GN YRL + +G G+F ++ L ++ T EVAIK+ + +P +L E ++ + Sbjct: 50 QPHIGN-YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMK 108 Query: 339 VLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSF--CNRKLSLKTVLMLADQMINR 512 +L + VK F V L + + S ++F + + ++ K Q+++ Sbjct: 109 ILNHP---NIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSA 165 Query: 513 VEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTG 692 V++ H K +HRD+K +N L+ + + DFG + ++ S + G Sbjct: 166 VQYCHQKRIVHRDLKAENLLLDADM---NIKITDFGFSNEFTVGS--------KLDTFCG 214 Query: 693 TARYASVSTHLGIEQSRRD-DMESLGYVLMYFLRGSLPWQG 812 + YA+ G + + D+ SLG +L + GSLP+ G Sbjct: 215 SPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDG 255
>Q03141:MARK3_MOUSE MAP/microtubule affinity-regulating kinase 3 - Mus musculus (Mouse)| Length = 753 Score = 65.5 bits (158), Expect = 8e-10 Identities = 56/221 (25%), Positives = 105/221 (47%), Gaps = 7/221 (3%) Frame = +3 Query: 171 EPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHP----QLLYESKLYR 338 +P +GN YRL + +G G+F ++ L ++ T EVAIK+ + +P +L E ++ + Sbjct: 50 QPHIGN-YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMK 108 Query: 339 VLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSF--CNRKLSLKTVLMLADQMINR 512 +L + VK F V L + + S ++F + + ++ K Q+++ Sbjct: 109 ILNHP---NIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSA 165 Query: 513 VEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTG 692 V++ H K +HRD+K +N L+ + + DFG + ++ S + G Sbjct: 166 VQYCHQKRIVHRDLKAENLLLDADM---NIKIADFGFSNEFTVGS--------KLDTFCG 214 Query: 693 TARYASVSTHLGIEQSRRD-DMESLGYVLMYFLRGSLPWQG 812 + YA+ G + + D+ SLG +L + GSLP+ G Sbjct: 215 SPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDG 255
>Q07174:M3K8_MOUSE Mitogen-activated protein kinase kinase kinase 8 - Mus musculus| (Mouse) Length = 467 Score = 65.5 bits (158), Expect = 8e-10 Identities = 55/207 (26%), Positives = 95/207 (45%), Gaps = 6/207 (2%) Frame = +3 Query: 204 RKLGSG-----SFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTGISN 368 R +GSG +FG++YL +++T + +A KL + P + +R Sbjct: 137 RNIGSGFVPRGAFGKVYLAQDMKTKKRMACKLIPIDQFKPSDVEIQACFRHENIAELYGA 196 Query: 369 VKWFGVEGDYNVLVMDV-LGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFLH 545 V W GD L M+ G S+ + C + ++ + ++ ++F+HSK +H Sbjct: 197 VLW----GDTVHLFMEAGEGGSVLEKLESCGPMREFE-IIWVTKHILKGLDFLHSKKVIH 251 Query: 546 RDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVSTHL 725 DIKP N + + + ++DFGL+ K + ++P K+L GT Y S L Sbjct: 252 HDIKPSNIVF----MSTKAVLVDFGLSVKMTE---DVYLP----KDLRGTEIYMSPEVIL 300 Query: 726 GIEQSRRDDMESLGYVLMYFLRGSLPW 806 S + D+ SLG L++ G+ PW Sbjct: 301 CRGHSTKADIYSLGATLIHMQTGTPPW 327
>Q61083:M3K2_MOUSE Mitogen-activated protein kinase kinase kinase 2 - Mus musculus| (Mouse) Length = 619 Score = 65.5 bits (158), Expect = 8e-10 Identities = 56/229 (24%), Positives = 96/229 (41%), Gaps = 9/229 (3%) Frame = +3 Query: 162 PPMEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKL--- 332 P PR +RLG+ LG G+FG +YL +V T E+A+K + P+ E Sbjct: 346 PSRSPRAPTNWRLGKLLGQGAFGRVYLCYDVDTGRELAVKQVQFNPESPETSKEVNALEC 405 Query: 333 -YRVLQGGTGISNVKWFGVEGDYNVLVMDVL-----GPSLEDLFSFCNRKLSLKTVLMLA 494 ++L+ V+++G D + + G S++D L+ Sbjct: 406 EIQLLKNLLHERIVQYYGCLRDPQEKTLSIFMELSPGGSIKDQLK-AYGALTENVTRKYT 464 Query: 495 DQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRE 674 Q++ V ++HS +HRDIK N L + + DFG +K+ + + Sbjct: 465 RQILEGVHYLHSNMIVHRDIKGANILR---DSTGNIKLGDFGASKRLQTIC----LSGTG 517 Query: 675 NKNLTGTARYASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKA 821 K++TGT + S G R+ D+ S+ ++ L PW +A Sbjct: 518 MKSVTGTPYWMSPEVISGEGYGRKADIWSVACTVVEMLTEKPPWAEFEA 566
>Q8K1Y2:KPCD3_MOUSE Serine/threonine-protein kinase D3 - Mus musculus (Mouse)| Length = 889 Score = 65.5 bits (158), Expect = 8e-10 Identities = 57/205 (27%), Positives = 98/205 (47%), Gaps = 6/205 (2%) Frame = +3 Query: 210 LGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHP-----QLLYESKLYRVLQGGTGISNVK 374 LGSG FG +Y G + +T +VAIK+ + K + P QL E + + L GI N++ Sbjct: 581 LGSGQFGIVYGGKHRKTGRDVAIKVID-KMRFPTKQESQLRNEVAILQNLHH-PGIVNLE 638 Query: 375 WFGVEGDYNVLVMDVL-GPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFLHRD 551 + +VM+ L G LE + S +L + + Q++ + +H K+ +H D Sbjct: 639 CMFETPERVFVVMEKLHGDMLEMILSSEKSRLPERITKFMVTQILVALRNLHFKNIVHCD 698 Query: 552 IKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVSTHLGI 731 +KP+N L+ + QV + DFG A+ + S +++ GT Y + Sbjct: 699 LKPENVLLASAEPFPQVKLCDFGFARIIGEKSF--------RRSVVGTPAYLAPEVLRSK 750 Query: 732 EQSRRDDMESLGYVLMYFLRGSLPW 806 +R DM S+G ++ L G+ P+ Sbjct: 751 GYNRSLDMWSVGVIVYVSLSGTFPF 775
>Q9N3Z3:CHK1_CAEEL Serine/threonine-protein kinase chk-1 - Caenorhabditis elegans| Length = 503 Score = 65.5 bits (158), Expect = 8e-10 Identities = 66/243 (27%), Positives = 103/243 (42%), Gaps = 8/243 (3%) Frame = +3 Query: 138 SVACVRARPPMEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNE-EVAIKLENVKTKHPQL 314 S A P +P + YR+ + LG G+FGE+ L N + E A+K N+ K Sbjct: 8 STPAAAAVAPQQPE--SLYRVVQTLGEGAFGEVLLIVNTKNPEVAAAMKKINIANKSKDF 65 Query: 315 LYESKLYRVLQ---GGTGISNV-KWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTV 482 + + +LQ G NV + G+ D + + +LF + V Sbjct: 66 IDNIRKEYLLQKRVSAVGHDNVIRMIGMRNDPQFYYLFLEYADGGELFDKIEPDCGMSPV 125 Query: 483 L--MLADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQ 656 Q+I ++FIH +HRDIKP+N L+ + + + DFG+A YR+ + Sbjct: 126 FAQFYFKQLICGLKFIHDNDVVHRDIKPENLLL---TGTHVLKISDFGMATLYRNKGEER 182 Query: 657 HIPYRENKNLTGTARYASVSTHLGIE-QSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKK 833 + GT YA+ G + + D+ S G VL+ L G LPW +A Sbjct: 183 LLDLS-----CGTIPYAAPELCAGKKYRGPPVDVWSSGIVLIAMLTGELPWD--RASDAS 235 Query: 834 QKY 842 Q Y Sbjct: 236 QSY 238
>Q6MAN0:PKND_PARUW Serine/threonine-protein kinase pknD - Protochlamydia amoebophila| (strain UWE25) Length = 982 Score = 65.1 bits (157), Expect = 1e-09 Identities = 77/302 (25%), Positives = 133/302 (44%), Gaps = 34/302 (11%) Frame = +3 Query: 192 YRLGRKLGSGSFGEIYLGTNVQTNEEVAIK-LENVKTKHPQL----LYESKLYRVLQGGT 356 Y++ + +G G GE++L + ++AIK + + +HPQ+ L E+ + L T Sbjct: 51 YQIIKSIGKGGMGEVFLAYDPCYERQIAIKKIRSDLLEHPQIKKRFLKEAHMTSQL---T 107 Query: 357 GISNVKWFGVEGDYNVLVMDVLGPSLE-DLFSFCNRKLSLK------------TVLMLAD 497 + + + + D + + P +E D RK L+ ++L L Sbjct: 108 HPAIIPIYTIRSDADTAYYTM--PFVEGDTLKQIIRKTKLQEKNGETLDYLGGSILALMR 165 Query: 498 QMIN---RVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPY 668 I V + HSK LHRD+KP+N ++G + +V ++D+GLA K+ D S + + Sbjct: 166 VFITICQAVAYAHSKGVLHRDLKPENIIIG---KYGEVLILDWGLA-KFIDQSPEEELLA 221 Query: 669 RENKNLT------------GTARYASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQG 812 ++LT GT Y + LG + + D+ SLG +L L P+ Sbjct: 222 SFPESLTKQKDITKIGKVVGTVAYMAPERALGQPATIQTDIYSLGVILYQLLTLKSPF-- 279 Query: 813 LKAGTKKQKYEKISERKIATSIEAL-CRGYPSEFQSFFHYCRSLRFEDSPDYQYLKRLFR 989 K GT + + +S + + A R P SF C SL ++ YQ ++ L R Sbjct: 280 -KRGTLDEFRKNMSREEWQDPVTAAPYREVPRMLASFTEKCLSLDLQNR--YQSVEELIR 336 Query: 990 DL 995 D+ Sbjct: 337 DI 338
>Q8NU97:PKN2_CORGL Serine/threonine protein kinases pknA - Corynebacterium glutamicum| (Brevibacterium flavum) Length = 469 Score = 65.1 bits (157), Expect = 1e-09 Identities = 71/272 (26%), Positives = 112/272 (41%), Gaps = 24/272 (8%) Frame = +3 Query: 150 VRARPPMEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKL--------------- 284 + + ++ +G YRL +G G ++L +V + EVAIK+ Sbjct: 6 ITGKDRLQELIGADYRLQWIIGHGGMSTVWLADDVVNDREVAIKVLRPEFSDNQEFLNRF 65 Query: 285 -------ENVKTKHPQLLYESKLYRVLQGGTGISNVKWFGVEGDYNVLVMD-VLGPSLED 440 EN+ ++H Y+ YR + G + + +VM+ V G SL D Sbjct: 66 RNEAQAAENIDSEHVVATYD---YREVPDPAGHT----------FCFIVMEFVRGESLAD 112 Query: 441 LFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMI-DF 617 L R L L + +Q + + IH +HRDIKP N L+ AN + I DF Sbjct: 113 LLEREGR-LPEDLALDVMEQAAHGLSVIHRMDMVHRDIKPGNMLI----TANGIVKITDF 167 Query: 618 GLAKKYRDTSTHQHIPYRENKNLTGTARYASVSTHLGIEQSRRDDMESLGYVLMYFLRGS 797 G+AK +P + GTA+Y S G E + D+ SLG V + G Sbjct: 168 GIAK------AAAAVPLTRTGMVVGTAQYVSPEQAQGKEVTAASDIYSLGVVGYEMMAGR 221 Query: 798 LPWQGLKAGTKKQKYEKISERKIATSIEALCR 893 P+ G + + + + ++ TSI A R Sbjct: 222 RPFTGDSSVSVAIAHINQAPPQMPTSISAQTR 253
>Q02595:KPK2_PLAFK Probable serine/threonine-protein kinase 2 - Plasmodium falciparum| (isolate K1 / Thailand) Length = 510 Score = 65.1 bits (157), Expect = 1e-09 Identities = 57/219 (26%), Positives = 96/219 (43%), Gaps = 10/219 (4%) Frame = +3 Query: 186 NKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK-LENVKTKHPQLLYESKLYRVLQGGTGI 362 N Y L +K+G GSF Y+GTN+ V +K ++ K K + E ++ R + I Sbjct: 109 NVYVLNKKIGKGSFSTAYIGTNILYGNRVVVKEVDKSKVKESNVYTEIEVLRKVMHKYII 168 Query: 363 SNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNR---------KLSLKTVLMLADQMINRV 515 + + EG + LV++ L +LF + N K ++K VL+ + Sbjct: 169 KLISAYEQEG-FVYLVLEYLKGG--ELFEYLNNNGPYTEQVAKKAMKRVLI-------AL 218 Query: 516 EFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGT 695 E +HS +HRD+K +N ++ + + +IDFGLA S + G+ Sbjct: 219 EALHSNGVVHRDLKMENLMLENPNDPSSLKIIDFGLASFLNSPSMNMR---------CGS 269 Query: 696 ARYASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQG 812 Y + + D+ SLG +L L G P++G Sbjct: 270 PGYVAPEILKCASYGTKVDIFSLGVILFNILCGYPPFRG 308
>O54833:CSK22_MOUSE Casein kinase II subunit alpha' - Mus musculus (Mouse)| Length = 350 Score = 65.1 bits (157), Expect = 1e-09 Identities = 49/165 (29%), Positives = 84/165 (50%), Gaps = 11/165 (6%) Frame = +3 Query: 174 PRVGNK--YRLGRKLGSGSFGEIYLGTNVQTNEEVAIK-LENVKTKHPQLLYESKLYRVL 344 P GN+ Y+L RKLG G + E++ N+ NE V +K L+ VK K ++ E K+ L Sbjct: 32 PSWGNQDDYQLVRKLGRGKYSEVFEAINITNNERVVVKILKPVKKK--KIKREVKILENL 89 Query: 345 QGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLAD--------Q 500 +GGT I +K V D + + +F + N + +L D + Sbjct: 90 RGGTNI--IKLIDT-------VKDPVSKTPALVFEYINNTDFKQLYQILTDFDIRFYMYE 140 Query: 501 MINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKY 635 ++ +++ HSK +HRD+KP N + + + ++ +ID+GLA+ Y Sbjct: 141 LLKALDYCHSKGIMHRDVKPHNVM--IDHQQKKLRLIDWGLAEFY 183
>P19784:CSK22_HUMAN Casein kinase II subunit alpha' - Homo sapiens (Human)| Length = 350 Score = 65.1 bits (157), Expect = 1e-09 Identities = 49/165 (29%), Positives = 84/165 (50%), Gaps = 11/165 (6%) Frame = +3 Query: 174 PRVGNK--YRLGRKLGSGSFGEIYLGTNVQTNEEVAIK-LENVKTKHPQLLYESKLYRVL 344 P GN+ Y+L RKLG G + E++ N+ NE V +K L+ VK K ++ E K+ L Sbjct: 32 PSWGNQDDYQLVRKLGRGKYSEVFEAINITNNERVVVKILKPVKKK--KIKREVKILENL 89 Query: 345 QGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLAD--------Q 500 +GGT I +K V D + + +F + N + +L D + Sbjct: 90 RGGTNI--IKLIDT-------VKDPVSKTPALVFEYINNTDFKQLYQILTDFDIRFYMYE 140 Query: 501 MINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKY 635 ++ +++ HSK +HRD+KP N + + + ++ +ID+GLA+ Y Sbjct: 141 LLKALDYCHSKGIMHRDVKPHNVM--IDHQQKKLRLIDWGLAEFY 183
>P20427:CSK22_BOVIN Casein kinase II subunit alpha' - Bos taurus (Bovine)| Length = 350 Score = 65.1 bits (157), Expect = 1e-09 Identities = 49/165 (29%), Positives = 84/165 (50%), Gaps = 11/165 (6%) Frame = +3 Query: 174 PRVGNK--YRLGRKLGSGSFGEIYLGTNVQTNEEVAIK-LENVKTKHPQLLYESKLYRVL 344 P GN+ Y+L RKLG G + E++ N+ NE V +K L+ VK K ++ E K+ L Sbjct: 32 PSWGNQDDYQLVRKLGRGKYSEVFEAINITNNERVVVKILKPVKKK--KIKREVKILENL 89 Query: 345 QGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLAD--------Q 500 +GGT I +K V D + + +F + N + +L D + Sbjct: 90 RGGTNI--IKLIDT-------VKDPVSKTPALVFEYINNTDFKQLYQILTDFDIRFYMYE 140 Query: 501 MINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKY 635 ++ +++ HSK +HRD+KP N + + + ++ +ID+GLA+ Y Sbjct: 141 LLKALDYCHSKGIMHRDVKPHNVM--IDHQQKKLRLIDWGLAEFY 183
>Q9Z0H0:CDC7_MOUSE Cell division cycle 7-related protein kinase - Mus musculus (Mouse)| Length = 564 Score = 65.1 bits (157), Expect = 1e-09 Identities = 48/160 (30%), Positives = 79/160 (49%), Gaps = 3/160 (1%) Frame = +3 Query: 174 PRVGNKYRLGRKLGSGSFGEIYLGT-NVQTNEEVAIKLEN-VKTKHP-QLLYESKLYRVL 344 P++ N ++ K+G G+F +YL T +Q E I L++ + T HP ++ E + V Sbjct: 46 PQLVNVSKIKDKIGEGTFSSVYLATAQLQEGHEEKIALKHLIPTSHPMRIAAELQCLTVA 105 Query: 345 QGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFI 524 G + +K+ + D+ V+ M L E N LS + V + ++ I Sbjct: 106 GGQDNVMGLKYCFRKNDHVVIAMPYL--EHESFLDILN-SLSFQEVREYMYNLFVALKRI 162 Query: 525 HSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDT 644 H +HRD+KP NFL +R + ++DFGLA+ RDT Sbjct: 163 HQFGIVHRDVKPSNFL--YNRRLKKYALVDFGLAQGTRDT 200
>O74304:WIN1_SCHPO MAP kinase kinase kinase win1 - Schizosaccharomyces pombe (Fission| yeast) Length = 1436 Score = 64.7 bits (156), Expect = 1e-09 Identities = 61/237 (25%), Positives = 98/237 (41%), Gaps = 28/237 (11%) Frame = +3 Query: 189 KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK---LENVKTKHPQLLYESKLYRVLQGGTG 359 +++ G +GSGSFG +Y N+ T + +A+K L + P + VL+ Sbjct: 1119 RWQQGGLIGSGSFGTVYRAVNLDTGDLMAVKEVALHKPRISRPMIKRIKGEMLVLELFDH 1178 Query: 360 ISNVKWFGVE---GDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHS 530 + V ++G+E N+ + G SL + + + L + + Q++ + +IHS Sbjct: 1179 PNVVSYYGIEVHREKVNIFMELCQGSSLFEFLRYGRIEDEL-VIQVYVLQLLEGLAYIHS 1237 Query: 531 KSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTH------------------- 653 H+D+KP+N L + DFG AK ST Sbjct: 1238 CGVSHQDVKPENILF---DHNGIMKFTDFGSAKMSGSASTKIFEQLTQQEEEEFEKDSEF 1294 Query: 654 -QHIPYRENKNLTGTARYASVSTHLGIEQSRRDDME--SLGYVLMYFLRGSLPWQGL 815 QH+ +LTGT Y + LG R M+ SLG V++ GS PW L Sbjct: 1295 LQHLDQNRGYSLTGTPTYMAPELILGNPSERVGAMDIWSLGCVIVEMATGSPPWPRL 1351
>O55047:TLK2_MOUSE Serine/threonine-protein kinase tousled-like 2 - Mus musculus (Mouse)| Length = 718 Score = 64.7 bits (156), Expect = 1e-09 Identities = 62/285 (21%), Positives = 118/285 (41%), Gaps = 18/285 (6%) Frame = +3 Query: 174 PRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKL---------ENVKTKHPQLLYES 326 P + ++Y L LG G F E+Y ++ VA+K+ E + H E Sbjct: 402 PTLNDRYLLLHLLGRGGFSEVYKAFDLTEQRYVAVKIHQLNKNWRDEKKENYHKHACREY 461 Query: 327 KLYRVLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMI 506 ++++ L + +F ++ D V++ + D + ++ +S K + Q++ Sbjct: 462 RIHKELDHPRIVKLYDYFSLDTDSFCTVLEYCEGNDLDFYLKQHKLMSEKEARSIIMQIV 521 Query: 507 NRVEFIHS--KSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENK 680 N +++++ +H D+KP N L+ G ++ + DFGL+K D S + Sbjct: 522 NALKYLNEIKPPIIHYDLKPGNILLVNGTACGEIKITDFGLSKIMDDDSYNSVDGMELTS 581 Query: 681 NLTGTARYASVSTHLGIEQ----SRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEK 848 GT Y + ++ S + D+ S+G + L G P+ G + + + Sbjct: 582 QGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFYQCLYGRKPF-----GHNQSQQDI 636 Query: 849 ISERKIATSIEALCRGYP---SEFQSFFHYCRSLRFEDSPDYQYL 974 + E I + E P E ++F C + R ED D Q L Sbjct: 637 LQENTILKATEVQFPPKPVVTPEAKAFIRRCLAYRKEDRIDVQQL 681
>Q86UE8:TLK2_HUMAN Serine/threonine-protein kinase tousled-like 2 - Homo sapiens (Human)| Length = 772 Score = 64.7 bits (156), Expect = 1e-09 Identities = 62/285 (21%), Positives = 118/285 (41%), Gaps = 18/285 (6%) Frame = +3 Query: 174 PRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKL---------ENVKTKHPQLLYES 326 P + ++Y L LG G F E+Y ++ VA+K+ E + H E Sbjct: 456 PTLNDRYLLLHLLGRGGFSEVYKAFDLTEQRYVAVKIHQLNKNWRDEKKENYHKHACREY 515 Query: 327 KLYRVLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMI 506 ++++ L + +F ++ D V++ + D + ++ +S K + Q++ Sbjct: 516 RIHKELDHPRIVKLYDYFSLDTDSFCTVLEYCEGNDLDFYLKQHKLMSEKEARSIIMQIV 575 Query: 507 NRVEFIHS--KSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENK 680 N +++++ +H D+KP N L+ G ++ + DFGL+K D S + Sbjct: 576 NALKYLNEIKPPIIHYDLKPGNILLVNGTACGEIKITDFGLSKIMDDDSYNSVDGMELTS 635 Query: 681 NLTGTARYASVSTHLGIEQ----SRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEK 848 GT Y + ++ S + D+ S+G + L G P+ G + + + Sbjct: 636 QGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFYQCLYGRKPF-----GHNQSQQDI 690 Query: 849 ISERKIATSIEALCRGYP---SEFQSFFHYCRSLRFEDSPDYQYL 974 + E I + E P E ++F C + R ED D Q L Sbjct: 691 LQENTILKATEVQFPPKPVVTPEAKAFIRRCLAYRKEDRIDVQQL 735
>Q03407:PKH1_YEAST Serine/threonine-protein kinase PKH1 - Saccharomyces cerevisiae| (Baker's yeast) Length = 766 Score = 64.7 bits (156), Expect = 1e-09 Identities = 74/295 (25%), Positives = 126/295 (42%), Gaps = 14/295 (4%) Frame = +3 Query: 192 YRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLEN----VKTKHPQLLYESKL-YRVLQGGT 356 ++ G +LG GS+ + L T + ++ A+K+ + ++ K + + KL + L G Sbjct: 125 FKFGEQLGDGSYSSVVLATARDSGKKYAVKVLSKEYLIRQKKVKYVTVEKLALQKLNGTK 184 Query: 357 GISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLM--LADQMINRVEFIHS 530 GI + +F + + ++ + P D + SL A Q+I+ V+ +H+ Sbjct: 185 GIFKL-FFTFQDEASLYFLLEYAPH-GDFLGLIKKYGSLNETCARYYASQIIDAVDSLHN 242 Query: 531 KSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAK--KYRDTSTHQHIP----YRENKNLTG 692 +HRDIKP+N L+ + +V + DFG AK ++T P Y ++K+ G Sbjct: 243 IGIIHRDIKPENILL---DKNMKVKLTDFGTAKILPEEPSNTADGKPYFDLYAKSKSFVG 299 Query: 693 TARYASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKISERKIAT 872 TA Y S R D+ + G +L L G P++ QK KI Sbjct: 300 TAEYVSPELLNDNYTDSRCDIWAFGCILYQMLAGKPPFKAANEYLTFQKVMKIQ------ 353 Query: 873 SIEALCRGYPSEFQSFFHYCRSLRFEDSPDYQYLKRLFRDLFIRE-GFQFDYVFD 1034 A G+P Q + L D D +K++ LF E F+ V+D Sbjct: 354 --YAFTAGFP---QIVKDLVKKLLVRDPNDRLTIKQIKAHLFFHEVNFEDGSVWD 403
>Q9Y2U5:M3K2_HUMAN Mitogen-activated protein kinase kinase kinase 2 - Homo sapiens| (Human) Length = 619 Score = 64.7 bits (156), Expect = 1e-09 Identities = 57/229 (24%), Positives = 97/229 (42%), Gaps = 9/229 (3%) Frame = +3 Query: 162 PPMEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKL--- 332 P PR +RLG+ LG G+FG +YL +V T E+A+K P+ E Sbjct: 346 PSRSPRAPTNWRLGKLLGQGAFGRVYLCYDVDTGRELAVKQVQFDPDSPETSKEVNALEC 405 Query: 333 -YRVLQGGTGISNVKWFGV-----EGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLA 494 ++L+ V+++G E ++ + + G S++D L+ Sbjct: 406 EIQLLKNLLHERIVQYYGCLRDPQEKTLSIFMEYMPGGSIKDQLK-AYGALTENVTRKYT 464 Query: 495 DQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRE 674 Q++ V ++HS +HRDIK N L V + DFG +K+ + + Sbjct: 465 RQILEGVHYLHSNMIVHRDIKGANILR---DSTGNVKLGDFGASKRLQTIC----LSGTG 517 Query: 675 NKNLTGTARYASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKA 821 K++TGT + S G R+ D+ S+ ++ L PW +A Sbjct: 518 MKSVTGTPYWMSPEVISGEGYGRKADIWSVACTVVEMLTEKPPWAEFEA 566
>Q15139:KPCD1_HUMAN Serine/threonine-protein kinase D1 - Homo sapiens (Human)| Length = 912 Score = 64.7 bits (156), Expect = 1e-09 Identities = 57/205 (27%), Positives = 96/205 (46%), Gaps = 6/205 (2%) Frame = +3 Query: 210 LGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHP-----QLLYESKLYRVLQGGTGISNVK 374 LGSG FG +Y G + +T +VAIK+ + K + P QL E + + L G+ N++ Sbjct: 589 LGSGQFGIVYGGKHRKTGRDVAIKIID-KLRFPTKQESQLRNEVAILQNLHH-PGVVNLE 646 Query: 375 WFGVEGDYNVLVMDVL-GPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFLHRD 551 + +VM+ L G LE + S +L L Q++ + +H K+ +H D Sbjct: 647 CMFETPERVFVVMEKLHGDMLEMILSSEKGRLPEHITKFLITQILVALRHLHFKNIVHCD 706 Query: 552 IKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVSTHLGI 731 +KP+N L+ QV + DFG A+ + S +++ GT Y + Sbjct: 707 LKPENVLLASADPFPQVKLCDFGFARIIGEKSF--------RRSVVGTPAYLAPEVLRNK 758 Query: 732 EQSRRDDMESLGYVLMYFLRGSLPW 806 +R DM S+G ++ L G+ P+ Sbjct: 759 GYNRSLDMWSVGVIIYVSLSGTFPF 783
>P27466:KCC1_YEAST Calcium/calmodulin-dependent protein kinase I - Saccharomyces| cerevisiae (Baker's yeast) Length = 446 Score = 64.7 bits (156), Expect = 1e-09 Identities = 40/156 (25%), Positives = 79/156 (50%), Gaps = 6/156 (3%) Frame = +3 Query: 189 KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK------LENVKTKHPQLLYESKLYRVLQG 350 KY G+ LG+G+FG + N +T E+VA+K L+ K + L E + + L Sbjct: 36 KYVFGKTLGAGTFGVVRQAKNTETGEDVAVKILIKKALKGNKVQLEALYDELDILQRLHH 95 Query: 351 GTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHS 530 ++ WF + + ++ G L D K + + + + ++++ V+++HS Sbjct: 96 PNIVAFKDWFESKDKFYIITQLAKGGELFDRI-LKKGKFTEEDAVRILVEILSAVKYMHS 154 Query: 531 KSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYR 638 ++ +HRD+KP+N L + + + DFG+AK+ + Sbjct: 155 QNIVHRDLKPENLLYIDKSDESPLVVADFGIAKRLK 190
>Q09437:YP62_CAEEL Putative serine/threonine-protein kinase B0495.2 - Caenorhabditis| elegans Length = 719 Score = 64.3 bits (155), Expect = 2e-09 Identities = 79/291 (27%), Positives = 130/291 (44%), Gaps = 14/291 (4%) Frame = +3 Query: 186 NKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK---LENVKTKHPQLLYESKLYRVLQGGT 356 ++Y ++ G+FG +Y G + +T+E VA+K +E K P + ++ +L+ G Sbjct: 354 DEYECVNRVDEGTFGVVYRGKDKRTDEIVALKRLKMEKEKEGFP-ITALREINMLLKAGN 412 Query: 357 --GISNVK--WFGVEGDYNVLVMDVLG---PSLEDLFSFCNRKLSLKTVLMLADQMINRV 515 I NVK G D + M+ + SL D S N++ S+ L Q+++ + Sbjct: 413 HPNIVNVKEILLGSNMDKIYMAMEFVEHDMKSLLDTMSRRNKRFSIGEQKTLLQQLLSGI 472 Query: 516 EFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGT 695 E +H LHRD+K N LM + + DFGLA++Y D P ++ ++ T Sbjct: 473 EHMHKLWILHRDLKTSNLLM---SHKGILKIADFGLAREYGD-------PLKKFTSIVVT 522 Query: 696 ARYASVSTHLGIE-QSRRDDMESLGYVLMYF--LRGSLPWQGLKAGTKKQKYEKISERKI 866 Y S LG S DM S+G ++ F L+ P +G KK E + Sbjct: 523 LWYRSPELLLGTRLYSTPVDMWSVGCIMAEFILLKPLFPGRGELEQIKKIFME------M 576 Query: 867 ATSIEALCRGYPSEFQSFFHYCRSLRFEDSPDYQYLKRLFRDLFIRE-GFQ 1016 T E++ G +E + ++L FE P Q KR + + GF+ Sbjct: 577 GTPTESIWPGV-TELDGW----KALTFEKYPYNQLRKRFLAGRLLNDTGFK 622
>Q91819:STK6L_XENLA Serine/threonine-protein kinase Eg2-like - Xenopus laevis (African| clawed frog) Length = 408 Score = 64.3 bits (155), Expect = 2e-09 Identities = 59/228 (25%), Positives = 97/228 (42%), Gaps = 6/228 (2%) Frame = +3 Query: 192 YRLGRKLGSGSFGEIYLGTNVQTNEEVAIK------LENVKTKHPQLLYESKLYRVLQGG 353 + +GR LG G FG +YL ++ +A+K LE +H QL E ++ L+ Sbjct: 140 FEIGRPLGKGKFGNVYLARERESKFILALKVLFKSQLEKAGVEH-QLRREVEIQSHLRHP 198 Query: 354 TGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSK 533 + +F +++ G L C R ++ L + Q+ + + HSK Sbjct: 199 NILRLYGYFHDASRVYLILDYAPGGELFRELQKCTRFDDQRSALYIK-QLAEALLYCHSK 257 Query: 534 SFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASV 713 +HRDIKP+N L+G ++ + DFG + H P L GT Y Sbjct: 258 KVIHRDIKPENLLLGSN---GELKIADFGWS---------VHAPSSRRTTLCGTLDYLPP 305 Query: 714 STHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKISE 857 G + D+ SLG + FL G P++ T ++ Y +IS+ Sbjct: 306 EMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFE---TDTHQETYRRISK 350
>Q00372:SNF1_CANGA Carbon catabolite derepressing protein kinase - Candida glabrata| (Yeast) (Torulopsis glabrata) Length = 612 Score = 64.3 bits (155), Expect = 2e-09 Identities = 64/231 (27%), Positives = 102/231 (44%), Gaps = 21/231 (9%) Frame = +3 Query: 177 RVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKT------------------- 299 RVGN Y++ + LG GSFG++ L +V T ++VA+K+ N K Sbjct: 35 RVGN-YQIVKTLGEGSFGKVKLAYHVTTGQKVALKIINKKVLAKSDMQGRIEREISYLRL 93 Query: 300 -KHPQLLYESKLYRVLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLK 476 +HP ++ KLY V++ D ++V++ G L D + K+S + Sbjct: 94 LRHPHII---KLYDVIK-------------SKDEIIMVIEYAGNELFD-YIVQRNKMSEQ 136 Query: 477 TVLMLADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQ 656 Q+I+ VE+ H +HRD+KP+N L L + N V + DFGL+ D + Sbjct: 137 EARRFFQQIISAVEYCHRHKIVHRDLKPENLL--LDEHLN-VKIADFGLSNIMTDGNF-- 191 Query: 657 HIPYRENKNLTGTARYASVSTHLG-IEQSRRDDMESLGYVLMYFLRGSLPW 806 K G+ YA+ G + D+ S G +L L LP+ Sbjct: 192 ------LKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYVMLCRRLPF 236
>Q63562:M3K8_RAT Mitogen-activated protein kinase kinase kinase 8 - Rattus| norvegicus (Rat) Length = 467 Score = 64.3 bits (155), Expect = 2e-09 Identities = 55/207 (26%), Positives = 95/207 (45%), Gaps = 6/207 (2%) Frame = +3 Query: 204 RKLGSG-----SFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTGISN 368 R +GSG +FG++YL +++T + +A KL V P + +R Sbjct: 137 RSIGSGFVPRGAFGKVYLAQDMKTKKRMACKLIPVDQFKPSDVEIQACFRHENIAELYGA 196 Query: 369 VKWFGVEGDYNVLVMDV-LGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFLH 545 V W GD L M+ G S+ + C + ++ + ++ ++F+HSK +H Sbjct: 197 VLW----GDTVHLFMEAGEGGSVLEKLESCGPMREFE-IIWVTKHVLKGLDFLHSKKVIH 251 Query: 546 RDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVSTHL 725 DIKP N + + + ++DFGL+ + + ++P K+L GT Y S L Sbjct: 252 HDIKPSNIVF----MSTKAVLVDFGLSVQMTE---DVYLP----KDLRGTEIYMSPEVIL 300 Query: 726 GIEQSRRDDMESLGYVLMYFLRGSLPW 806 S + D+ SLG L++ G+ PW Sbjct: 301 CRGHSTKADIYSLGATLIHMQTGTPPW 327
>P21869:CSK22_CHICK Casein kinase II subunit alpha' - Gallus gallus (Chicken)| Length = 350 Score = 64.3 bits (155), Expect = 2e-09 Identities = 48/165 (29%), Positives = 83/165 (50%), Gaps = 11/165 (6%) Frame = +3 Query: 174 PRVGNK--YRLGRKLGSGSFGEIYLGTNVQTNEEVAIK-LENVKTKHPQLLYESKLYRVL 344 P GN+ Y+L RKLG G + E++ N+ NE V +K L+ VK K ++ E K+ L Sbjct: 32 PSWGNQDDYQLVRKLGRGKYSEVFEAINITNNERVVVKILKPVKKK--KIKREVKILENL 89 Query: 345 QGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLAD--------Q 500 +GGT I N+ V D + + +F + N + +L D + Sbjct: 90 RGGTNIINL---------IDTVKDPVSKTPALVFEYINNTDFKQLYQILTDFDIRFYMYE 140 Query: 501 MINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKY 635 ++ +++ HS +HRD+KP N + + + ++ +ID+GLA+ Y Sbjct: 141 LLKALDYCHSMGIMHRDVKPHNVM--IDHQQKKLRLIDWGLAEFY 183
>O96017:CHK2_HUMAN Serine/threonine-protein kinase Chk2 - Homo sapiens (Human)| Length = 543 Score = 64.3 bits (155), Expect = 2e-09 Identities = 66/253 (26%), Positives = 110/253 (43%), Gaps = 19/253 (7%) Frame = +3 Query: 186 NKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKL--------ENVKTKHPQLLYESKL--Y 335 ++Y + + LGSG+ GE+ L +T ++VAIK+ + + P L E+++ Sbjct: 218 DEYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIEIL 277 Query: 336 RVLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRV 515 + L I +F E Y VL + G + + N++L T + QM+ V Sbjct: 278 KKLNHPCIIKIKNFFDAEDYYIVLELMEGGELFDKVVG--NKRLKEATCKLYFYQMLLAV 335 Query: 516 EFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGT 695 +++H +HRD+KP+N L+ + + + DFG +K +TS + L GT Sbjct: 336 QYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSL--------MRTLCGT 387 Query: 696 ARYASVSTHLGI---EQSRRDDMESLGYVLMYFLRGSLPWQ------GLKAGTKKQKYEK 848 Y + + + +R D SLG +L L G P+ LK KY Sbjct: 388 PTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNF 447 Query: 849 ISERKIATSIEAL 887 I E S +AL Sbjct: 448 IPEVWAEVSEKAL 460
>P53682:CDPK1_ORYSJ Calcium-dependent protein kinase, isoform 1 - Oryza sativa subsp.| japonica (Rice) Length = 534 Score = 64.3 bits (155), Expect = 2e-09 Identities = 64/238 (26%), Positives = 105/238 (44%), Gaps = 7/238 (2%) Frame = +3 Query: 174 PRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKL---ENVK--TKHPQLLYESKLYR 338 P V Y LGR+LG G FG+ YL T + T + A K N++ + + E ++ Sbjct: 67 PNVRELYTLGRELGQGQFGKTYLCTEISTGCQYACKTILKSNLRCVSDIEDVRREIQIMH 126 Query: 339 VLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRK--LSLKTVLMLADQMINR 512 L G I +K + +VM++ +LFS ++ S + L ++ Sbjct: 127 HLSGQKNIVTIKDTYEDEQAVHIVMELCAGG--ELFSKIQKRGHYSERKAAELIKIIVGI 184 Query: 513 VEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTG 692 +E HS +HRD+KP+NFL+ V IDFGL+ +R P + + + G Sbjct: 185 IETCHSHGVMHRDLKPENFLLLDADDEFSVKAIDFGLSVFFR--------PGQVFREVVG 236 Query: 693 TARYASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKISERKI 866 + Y + L D+ + G +L L G P+ A T+ YEK+ + +I Sbjct: 237 SPYYIAPEV-LEKRYGPEADIWTAGVILYVLLTGVPPFW---ADTQSGIYEKVLDGRI 290
>Q8MYQ1:Y31E_CAEEL Putative serine/threonine-protein kinase F31E3.2 - Caenorhabditis| elegans Length = 441 Score = 63.9 bits (154), Expect = 2e-09 Identities = 56/216 (25%), Positives = 98/216 (45%), Gaps = 8/216 (3%) Frame = +3 Query: 198 LGRKLGSGSFGEIYLGTNVQTNE-EVAIKLENV-----KTKHPQLLYESKLYRVLQGGTG 359 L R+LG GSFG +Y + + +E + AIK++ K Q+ E+ + R+L Sbjct: 128 LERQLGRGSFGVVYCASAIHDSERKFAIKMQEKREIISKRAVLQVKREASIQRLLPSHPF 187 Query: 360 ISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLK--TVLMLADQMINRVEFIHSK 533 I+ + ++ S DLFS ++ SL + ++ ++ + ++F+H Sbjct: 188 IARTYSTWQTRTHLYSLLQYPTGSTGDLFSVWRQRGSLSEAAIRLIGAELASAIDFLHQN 247 Query: 534 SFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASV 713 ++RD+K +N ++ + +IDFGLAKK + S+ + GT +Y S Sbjct: 248 DVIYRDVKLENVVL---DQWGHALLIDFGLAKKLKQGSS--------TGTICGTLQYMSP 296 Query: 714 STHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKA 821 G S D SLG +L L G P+ +A Sbjct: 297 DVASGGTYSHYVDWWSLGVLLHILLTGIYPYPNSEA 332
>O94168:SNF1_CANTR Carbon catabolite derepressing protein kinase - Candida tropicalis| (Yeast) Length = 619 Score = 63.9 bits (154), Expect = 2e-09 Identities = 66/240 (27%), Positives = 102/240 (42%), Gaps = 26/240 (10%) Frame = +3 Query: 165 PMEPRVGNKYRLGR-----KLGSGSFGEIYLGTNVQTNEEVAIKLENVKT---------- 299 P++P V R+GR LG GSFG++ L +V T ++VA+K+ N KT Sbjct: 38 PIDPNVNPANRIGRYQIIKTLGEGSFGKVKLAQHVGTGQKVALKIINRKTLAKSDMQGRV 97 Query: 300 ----------KHPQLLYESKLYRVLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFS 449 +HP ++ KLY V++ D ++V++ G L D + Sbjct: 98 EREISYLRLLRHPHII---KLYDVIK-------------SKDEIIMVIEFAGKELFD-YI 140 Query: 450 FCNRKLSLKTVLMLADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAK 629 K+ Q+I VE+ H +HRD+KP+N L L + N V + DFGL+ Sbjct: 141 VQRGKMPEDEARRFFQQIIAAVEYCHRHKIVHRDLKPENLL--LDDQLN-VKIADFGLSN 197 Query: 630 KYRDTSTHQHIPYRENKNLTGTARYASVSTHLG-IEQSRRDDMESLGYVLMYFLRGSLPW 806 D + K G+ YA+ G + D+ S G +L L G LP+ Sbjct: 198 IMTDGNF--------LKTSCGSPNYAAPEVISGKLYAGPEVDVWSSGVILYVMLCGRLPF 249
>Q255D2:PKND_CHLFF Serine/threonine-protein kinase pknD - Chlamydophila felis (strain| Fe/C-56) Length = 933 Score = 63.9 bits (154), Expect = 2e-09 Identities = 66/254 (25%), Positives = 115/254 (45%), Gaps = 27/254 (10%) Frame = +3 Query: 189 KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK-----LENVKTKHPQLLYESKLYRVLQGG 353 +Y + R +G G GE+YL + + +VA+K L + + + L E+K+ L Sbjct: 3 RYDIIRMIGKGGMGEVYLAYDPVCSRKVALKRIREDLSDNELLKKRFLREAKIAADLVH- 61 Query: 354 TGISNVKWFGVEGDYNVLVMDVL-GPSLEDLFSF---CN-------RKLSLKTVLMLADQ 500 G+ V + D M + G +L+ L C+ + S+ T L + + Sbjct: 62 PGVVPVFTICSDSDPVYYTMPYIEGYTLKSLLKSVWQCDSLPKDLAEQTSVGTFLSIFHK 121 Query: 501 MINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLA---KKYRDTSTHQHIPYR 671 + + VE++HS+ LHRD+KPDN L+GL ++V ++D+G A + + IP Sbjct: 122 ICSTVEYVHSRGILHRDLKPDNILLGL---FSEVVILDWGAALSKEMQEEVLLDIDIPVT 178 Query: 672 EN--KNLT------GTARYASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGT 827 + N+T GT Y + G S D+ +LG +L L S P++ K Sbjct: 179 GSMFSNMTIPGKIVGTPDYMAPERLRGTPASESTDIYALGVILYQMLTLSFPYRNKKGKK 238 Query: 828 KKQKYEKISERKIA 869 +++ S +IA Sbjct: 239 ISFRHQISSPEEIA 252
>O22042:M3K3_ARATH Mitogen-activated protein kinase kinase kinase 3 - Arabidopsis| thaliana (Mouse-ear cress) Length = 651 Score = 63.9 bits (154), Expect = 2e-09 Identities = 59/227 (25%), Positives = 103/227 (45%), Gaps = 12/227 (5%) Frame = +3 Query: 162 PPMEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK--------LENVKTK-HPQL 314 P E ++R G +G G+FG +Y+G N+ + E +AIK KT+ H + Sbjct: 58 PRKEEAPSIRWRKGELIGCGAFGRVYMGMNLDSGELLAIKQVLIAPSSASKEKTQGHIRE 117 Query: 315 LYESKLYRVLQGGTGISNVKWFGV--EGD-YNVLVMDVLGPSLEDLFSFCNRKLSLKTVL 485 L E ++L+ + + V++ G E D N+L+ V G S+ L ++ Sbjct: 118 LEEE--VQLLKNLSHPNIVRYLGTVRESDSLNILMEFVPGGSISSLLEKFG-SFPEPVII 174 Query: 486 MLADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIP 665 M Q++ +E++H+ +HRDIK N L+ + + DFG +KK + +T Sbjct: 175 MYTKQLLLGLEYLHNNGIMHRDIKGANILV---DNKGCIRLADFGASKKVVELAT----- 226 Query: 666 YRENKNLTGTARYASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPW 806 K++ GT + + L S D+ S+G ++ G PW Sbjct: 227 VNGAKSMKGTPYWMAPEVILQTGHSFSADIWSVGCTVIEMATGKPPW 273
>Q01919:KIN4_YEAST Serine/threonine-protein kinase KIN4 - Saccharomyces cerevisiae| (Baker's yeast) Length = 800 Score = 63.9 bits (154), Expect = 2e-09 Identities = 59/219 (26%), Positives = 102/219 (46%), Gaps = 14/219 (6%) Frame = +3 Query: 192 YRLGRKLGSGSFGEIYLG-----TNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGT 356 Y +G LG G FG++ LG ++ + ++VAIKL T E K+YR + Sbjct: 46 YIIGSTLGEGEFGKVKLGWTKASSSNEVPKQVAIKLIRRDTIKKDADKEIKIYREINALK 105 Query: 357 GISNVKWFGVE-----GDYNVLVMDVLGPSLEDLFSFCNRKLSLK--TVLMLADQMINRV 515 +++ +E Y +V++ + + + + RK LK + L Q+I+ V Sbjct: 106 HLTHPNIIYLEEVLQNSKYIGIVLEFVSGG--EFYKYIQRKRRLKESSACRLFAQLISGV 163 Query: 516 EFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGT 695 ++H K +HRD+K +N L L K N V + DFG ++ + + K G+ Sbjct: 164 NYMHYKGLVHRDLKLENLL--LDKHENLV-ITDFGFVNEFFEDNELM-------KTSCGS 213 Query: 696 ARYASVSTHLGIE--QSRRDDMESLGYVLMYFLRGSLPW 806 YA+ + + ++R+ D+ S G +L L G LPW Sbjct: 214 PCYAAPELVVSTKAYEARKADVWSCGVILYAMLAGYLPW 252
>P92958:KIN11_ARATH SNF1-related protein kinase catalytic subunit alpha KIN11 -| Arabidopsis thaliana (Mouse-ear cress) Length = 512 Score = 63.9 bits (154), Expect = 2e-09 Identities = 60/211 (28%), Positives = 94/211 (44%), Gaps = 6/211 (2%) Frame = +3 Query: 192 YRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVK-----TKHPQLLYESKLYRVLQGGT 356 Y+LG+ LG GSFG++ + +V T +VAIK+ N + ++ E K+ R+ Sbjct: 20 YKLGKTLGIGSFGKVKIAEHVVTGHKVAIKILNRRKIKNMEMEEKVRREIKILRLFMHPH 79 Query: 357 GISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKS 536 I + D V++ V L D + +L Q+I+ VE+ H Sbjct: 80 IIRQYEVIETTSDIYVVMEYVKSGELFD-YIVEKGRLQEDEARNFFQQIISGVEYCHRNM 138 Query: 537 FLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVS 716 +HRD+KP+N L L R N + + DFGL+ RD K G+ YA+ Sbjct: 139 VVHRDLKPENLL--LDSRCN-IKIADFGLSNVMRDG--------HFLKTSCGSPNYAAPE 187 Query: 717 THLG-IEQSRRDDMESLGYVLMYFLRGSLPW 806 G + D+ S G +L L G+LP+ Sbjct: 188 VISGKLYAGPEVDVWSCGVILYALLCGTLPF 218
>Q00771:KCC1_EMENI Calcium/calmodulin-dependent protein kinase - Emericella nidulans| (Aspergillus nidulans) Length = 414 Score = 63.9 bits (154), Expect = 2e-09 Identities = 53/210 (25%), Positives = 95/210 (45%), Gaps = 4/210 (1%) Frame = +3 Query: 192 YRLGRKLGSGSFGEIYLGTNVQTNEEVAIKL---ENVKTKHPQLLYESKLYRVLQGGTGI 362 YR GR LG+G++G + ++ +VA+K+ NV+ + E L + L + Sbjct: 23 YRFGRTLGAGTYGIVREADC--SSGKVAVKIILKRNVRGNERMVYDELDLLQKLNHPHIV 80 Query: 363 SNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNR-KLSLKTVLMLADQMINRVEFIHSKSF 539 V WF + + ++ G L D C K + K Q+++ V ++H ++ Sbjct: 81 HFVDWFESKDKFYIVTQLATGGELFD--RICEYGKFTEKDASQTIRQVLDAVNYLHQRNI 138 Query: 540 LHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVST 719 +HRD+KP+N L +Q+ + DFG+AK + P ++ G+ YA+ Sbjct: 139 VHRDLKPENLLYLTRDLDSQLVLADFGIAKMLDN-------PAEVLTSMAGSFGYAAPEV 191 Query: 720 HLGIEQSRRDDMESLGYVLMYFLRGSLPWQ 809 L + D+ SLG + L G P++ Sbjct: 192 MLKQGHGKAVDIWSLGVITYTLLCGYSPFR 221
>P83101:GSK3H_DROME Putative glycogen synthase kinase-3 homolog - Drosophila| melanogaster (Fruit fly) Length = 501 Score = 63.9 bits (154), Expect = 2e-09 Identities = 65/219 (29%), Positives = 100/219 (45%), Gaps = 12/219 (5%) Frame = +3 Query: 192 YRLGRKLGSGSFGEIYLGTNVQTNEEVAIK--LENVKTKHPQLLYESKLYRVLQGGTGIS 365 Y + +G+GSFG ++ V +NE VAIK L++ + K+ +L KL I Sbjct: 33 YTDAKVVGNGSFGVVFQAKMVPSNEMVAIKKVLQDRRFKNRELQIMRKLRH-----DNII 87 Query: 366 NVKWF----GVEGD--YNVLVMDVLGPSL---EDLFSFCNRKLSLKTVLMLADQMINRVE 518 +KWF G + D Y LVM+ L +L E ++ + L + V + Q++ + Sbjct: 88 TLKWFFFSSGEKRDEVYLNLVMEFLPETLYKVERQYARAKQTLPVNFVRLYMYQLLRSMG 147 Query: 519 FIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTA 698 ++HS F HRDIKP N L L + + DFG AK Q I N + + Sbjct: 148 YLHSLGFCHRDIKPQNML--LDSETGVLKLCDFGSAK--------QLISGEPNVSYICSR 197 Query: 699 RYASVSTHLG-IEQSRRDDMESLGYVLMYFLRGSLPWQG 812 Y + G + + + DM S G V+ L G L + G Sbjct: 198 YYRAPELIFGSTDYTTKIDMWSAGCVMSELLLGQLIFPG 236
>P39688:FYN_MOUSE Proto-oncogene tyrosine-protein kinase Fyn - Mus musculus (Mouse)| Length = 537 Score = 63.9 bits (154), Expect = 2e-09 Identities = 67/278 (24%), Positives = 118/278 (42%), Gaps = 10/278 (3%) Frame = +3 Query: 195 RLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQ-LLYESKLYRVLQGGTGISNV 371 +L ++LG+G FGE++LGT N +VAIK T P+ L E+++ + L+ + Sbjct: 272 QLIKRLGNGQFGEVWLGT-WNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLY 330 Query: 372 KWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFLHRD 551 E Y V G L+ L R L L ++ +A Q+ + +I +++HRD Sbjct: 331 AVVSEEPIYIVTEYMSKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRD 390 Query: 552 IKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVSTHLGI 731 ++ N L+G G + DFGLA+ D Y + ++ + L Sbjct: 391 LRSANILVGNGLICK---IADFGLARLIEDNE------YTARQGAKFPIKWTAPEAALYG 441 Query: 732 EQSRRDDMESLGYVLMYFL-RGSLPWQGLKAGTKKQKYEKISERKIATSIEALCRGY--- 899 + + D+ S G +L + +G +P+ G+ + R++ +E RGY Sbjct: 442 RFTIKSDVWSFGILLTELVTKGRVPYPGM------------NNREVLEQVE---RGYRMP 486 Query: 900 -----PSEFQSFFHYCRSLRFEDSPDYQYLKRLFRDLF 998 P +C E+ P ++YL+ D F Sbjct: 487 CPQDCPISLHELMIHCWKKDPEERPTFEYLQGFLEDYF 524
>O75385:ULK1_HUMAN Serine/threonine-protein kinase ULK1 - Homo sapiens (Human)| Length = 1050 Score = 63.5 bits (153), Expect = 3e-09 Identities = 64/244 (26%), Positives = 105/244 (43%), Gaps = 17/244 (6%) Frame = +3 Query: 168 MEPRVGN-----KYRLGRK--LGSGSFGEIYLGTNVQTNE-EVAIKLENVKTKHPQLLYE 323 MEP G K+ RK +G G+F ++ G + + ++ EVA+K N K Sbjct: 1 MEPGRGGTETVGKFEFSRKDLIGHGAFAVVFKGRHREKHDLEVAVKCINKKNLAKSQTLL 60 Query: 324 SKLYRVLQGGTGISNVKWFGVEGDYN--VLVMDVL-GPSLEDLFSFCNRKLSLKTVLMLA 494 K ++L+ + V + + N LVM+ G L D + R LS T+ + Sbjct: 61 GKEIKILKELKHENIVALYDFQEMANSVYLVMEYCNGGDLAD-YLHAMRTLSEDTIRLFL 119 Query: 495 DQMINRVEFIHSKSFLHRDIKPDNFLMG--LGKRAN----QVYMIDFGLAKKYRDTSTHQ 656 Q+ + +HSK +HRD+KP N L+ G+RAN +V + DFG A+ + Sbjct: 120 QQIAGAMRLLHSKGIIHRDLKPQNILLSNPAGRRANPNSIRVKIADFGFARYLQSNMM-- 177 Query: 657 HIPYRENKNLTGTARYASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQ 836 L G+ Y + + + D+ S+G ++ L G P+Q + Sbjct: 178 ------AATLCGSPMYMAPEVIMSQHYDGKADLWSIGTIVYQCLTGKAPFQASSPQDLRL 231 Query: 837 KYEK 848 YEK Sbjct: 232 FYEK 235
>Q6CVA2:STE20_KLULA Serine/threonine-protein kinase STE20 - Kluyveromyces lactis (Yeast)| (Candida sphaerica) Length = 989 Score = 63.5 bits (153), Expect = 3e-09 Identities = 49/203 (24%), Positives = 97/203 (47%), Gaps = 3/203 (1%) Frame = +3 Query: 207 KLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTGISNVKWFG- 383 K+G G+ G +Y + TN VAIK N++ + + L +++ V++G + V + Sbjct: 703 KIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVNEIL-VMKGSKHNNIVNFIDS 761 Query: 384 --VEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFLHRDIK 557 GD V++ + G SL D+ + C L+ + ++ + + ++F+HSK +HRDIK Sbjct: 762 YLFRGDLWVVMEYMEGGSLTDVVTHCI--LTEGQIGAVSRETLKGLQFLHSKGVIHRDIK 819 Query: 558 PDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVSTHLGIEQ 737 DN L+ + + + DFG + + + + + GT + + E Sbjct: 820 SDNILLSMN---GDIKLTDFGFCAQINEVNL-------KRTTMVGTPYWMAPEVVSRKEY 869 Query: 738 SRRDDMESLGYVLMYFLRGSLPW 806 + D+ SLG +++ + G P+ Sbjct: 870 GPKVDIWSLGIMIIEMIEGEPPY 892
>P65732:PKNJ_MYCTU Probable serine/threonine-protein kinase pknJ - Mycobacterium| tuberculosis Length = 589 Score = 63.5 bits (153), Expect = 3e-09 Identities = 52/212 (24%), Positives = 88/212 (41%), Gaps = 7/212 (3%) Frame = +3 Query: 192 YRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTGISNV 371 YR+ R LG+G G +YL N A+K+ + L + ++ R G+ + Sbjct: 14 YRIERMLGAGGMGTVYLARNPDLPRSEALKVLAAELSR-DLDFRARFVREADVAAGLDHP 72 Query: 372 KWFGV------EGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSK 533 V EG + + V G + ED ++ + + ++ +++ H + Sbjct: 73 NIVAVHQRGQFEGRLWIAMQFVDGGNAEDALRAAT--MTTARAVYVIGEVAKALDYAHQQ 130 Query: 534 SFLHRDIKPDNFLMGLGKRANQ-VYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYAS 710 +HRDIKP NFL+ ++ V + DFG+A+ DT ++ T YA+ Sbjct: 131 GVIHRDIKPANFLLSRAAGGDERVLLSDFGIARALGDTG------LTSTGSVLATLAYAA 184 Query: 711 VSTHLGIEQSRRDDMESLGYVLMYFLRGSLPW 806 G R D+ SLG L L G P+ Sbjct: 185 PEVLAGQGFDGRADLYSLGCALFRLLTGEAPF 216
>P65733:PKNJ_MYCBO Probable serine/threonine-protein kinase pknJ - Mycobacterium bovis| Length = 589 Score = 63.5 bits (153), Expect = 3e-09 Identities = 52/212 (24%), Positives = 88/212 (41%), Gaps = 7/212 (3%) Frame = +3 Query: 192 YRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTGISNV 371 YR+ R LG+G G +YL N A+K+ + L + ++ R G+ + Sbjct: 14 YRIERMLGAGGMGTVYLARNPDLPRSEALKVLAAELSR-DLDFRARFVREADVAAGLDHP 72 Query: 372 KWFGV------EGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSK 533 V EG + + V G + ED ++ + + ++ +++ H + Sbjct: 73 NIVAVHQRGQFEGRLWIAMQFVDGGNAEDALRAAT--MTTARAVYVIGEVAKALDYAHQQ 130 Query: 534 SFLHRDIKPDNFLMGLGKRANQ-VYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYAS 710 +HRDIKP NFL+ ++ V + DFG+A+ DT ++ T YA+ Sbjct: 131 GVIHRDIKPANFLLSRAAGGDERVLLSDFGIARALGDTG------LTSTGSVLATLAYAA 184 Query: 711 VSTHLGIEQSRRDDMESLGYVLMYFLRGSLPW 806 G R D+ SLG L L G P+ Sbjct: 185 PEVLAGQGFDGRADLYSLGCALFRLLTGEAPF 216
>O08679:MARK2_RAT Serine/threonine-protein kinase MARK2 - Rattus norvegicus (Rat)| Length = 722 Score = 63.5 bits (153), Expect = 3e-09 Identities = 104/493 (21%), Positives = 197/493 (39%), Gaps = 44/493 (8%) Frame = +3 Query: 171 EPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK-LENVKTKHPQLLYESKLYRVLQ 347 +P +GN YRL + +G G+F ++ L ++ T +EVA+K ++ + L + R+++ Sbjct: 47 QPHIGN-YRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMK 105 Query: 348 GGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSF--CNRKLSLKTVLMLADQMINRVEF 521 + VK F V L + + S ++F + + ++ K Q+++ V++ Sbjct: 106 VLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQY 165 Query: 522 IHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTAR 701 H K +HRD+K +N L+ + + DFG + ++ + + G+ Sbjct: 166 CHQKFIVHRDLKAENLLLDADM---NIKIADFGFSNEFTFGN--------KLDTFCGSPP 214 Query: 702 YASVSTHLGIEQSRRD-DMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKISERK----- 863 YA+ G + + D+ SLG +L + GSLP+ G K+ E++ K Sbjct: 215 YAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNL---KELRERVLRGKYRIPF 271 Query: 864 -IATSIEALCRGY----PSE-----------FQSFFHYCRSLR--FEDSPDYQYLKRLFR 989 ++T E L + + PS+ + + H L+ E PDY+ +R Sbjct: 272 YMSTDCENLLKKFLILNPSKRGTLEQIMKDRWMNVGHEDDELKPYVEPLPDYKDPRR--T 329 Query: 990 DLFIREGFQFDYVFD-------------WTILKYQQSQM----TSVPPRAIAAAAGQSSG 1118 +L + G+ + + D + +L Y+ S++ ++ PR A S+ Sbjct: 330 ELMVSMGYTREEIQDSLVGQRYNEVMATYLLLGYKSSELEGDTITLKPRPSADLTNSSAP 389 Query: 1119 MAPIASNNRLSATEEGRISGWSADPTRSQVPPTGINAGSLSKQKSPVRPDLSAPKEAVLS 1298 +SA + R S Q P + S SK+ + P+E Sbjct: 390 SPSHKVQRSVSANPKQRRSS-------DQAVPAIPTSNSYSKKTQSNNAENKRPEEET-- 440 Query: 1299 SSTFLGRSGVFSRRPAVSSSRDLPSSEAEPSRSRAPDVSPGTFQRNSAPRRASHTLDYSD 1478 GR + + S L + P+ S +S T + ++P LD + Sbjct: 441 -----GRKASSTAKVPASPLPGLDRKKTTPTPSTNSVLSTSTNRSRNSP-----LLDRAS 490 Query: 1479 PRHKSISNNYEST 1517 SI N +ST Sbjct: 491 LGQASIQNGKDST 503
>Q9P0L2:MARK1_HUMAN Serine/threonine-protein kinase MARK1 - Homo sapiens (Human)| Length = 795 Score = 63.5 bits (153), Expect = 3e-09 Identities = 55/221 (24%), Positives = 105/221 (47%), Gaps = 7/221 (3%) Frame = +3 Query: 171 EPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHP----QLLYESKLYR 338 +P +GN YRL + +G G+F ++ L +V T EVA+K+ + +P +L E ++ + Sbjct: 54 QPHIGN-YRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMK 112 Query: 339 VLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSF--CNRKLSLKTVLMLADQMINR 512 +L + VK F V L + + S ++F + + ++ K Q+++ Sbjct: 113 ILNHP---NIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSA 169 Query: 513 VEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTG 692 V++ H K +HRD+K +N L+ + + DFG + ++ + + G Sbjct: 170 VQYCHQKYIVHRDLKAENLLL---DGDMNIKIADFGFSNEFTVGN--------KLDTFCG 218 Query: 693 TARYASVSTHLGIEQSRRD-DMESLGYVLMYFLRGSLPWQG 812 + YA+ G + + D+ SLG +L + GSLP+ G Sbjct: 219 SPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDG 259
>Q6X4A2:CIPK1_ORYSJ CIPK-like protein 1 - Oryza sativa subsp. japonica (Rice)| Length = 449 Score = 63.5 bits (153), Expect = 3e-09 Identities = 65/242 (26%), Positives = 109/242 (45%), Gaps = 10/242 (4%) Frame = +3 Query: 162 PPMEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKL---ENVKTKH---PQLLYE 323 P ++ RVG KY LGR +G G+F ++ N + +E VAIK+ E V+ KH Q+ E Sbjct: 11 PKVKRRVG-KYELGRTIGEGTFAKVRFAKNTENDEPVAIKILDKEKVQ-KHRLVEQIRRE 68 Query: 324 SKLYRVLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQM 503 ++++ + + G + +++ V G L ++ + N +L + Q+ Sbjct: 69 ICTMKLVKHPNVVRLFEVMGSKARIFIVLEYVTGGELFEIIA-TNGRLKEEEARKYFQQL 127 Query: 504 INRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKN 683 IN V++ HS+ HRD+K +N L+ + + + DFGL+ + Sbjct: 128 INAVDYCHSRGVYHRDLKLENLLL---DASGNLKVSDFGLSALTEQVKADGLL-----HT 179 Query: 684 LTGTARYASVSTHLGIEQSRRD----DMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKI 851 GT Y + IE D D+ S G +L L G LP++ Y+KI Sbjct: 180 TCGTPNYVAPEV---IEDRGYDGAAADIWSCGVILYVLLAGFLPFED---DNIIALYKKI 233 Query: 852 SE 857 SE Sbjct: 234 SE 235
>Q03002:YP141_YEAST Putative serine/threonine-protein kinase YPL141C - Saccharomyces| cerevisiae (Baker's yeast) Length = 865 Score = 63.2 bits (152), Expect = 4e-09 Identities = 65/225 (28%), Positives = 100/225 (44%), Gaps = 20/225 (8%) Frame = +3 Query: 192 YRLGRKLGSGSFGEIYLG----------TNVQTNEEVAIKLENVKTKHPQLLYESKLYRV 341 Y LG LG G FG++ LG + ++VAIKL + E K+YR Sbjct: 41 YILGSTLGEGEFGKVKLGWPKNFSNSSNSTFDFPKQVAIKLIKRDSISNDYRKEVKIYRE 100 Query: 342 LQGGTGISNVKWFGVEGDYNVLVMD-VLGPSLE-----DLFSFCNRKLSLKTV--LMLAD 497 + +S+ +E VL +G LE + + + +K LK + L Sbjct: 101 INALKHLSHPNIVKLE---EVLQNSRYIGIVLEYACGGEFYKYIQKKRRLKEMNACRLFS 157 Query: 498 QMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYREN 677 Q+I+ V +IHSK +HRD+K +N L L K N V + DFG ++ + Sbjct: 158 QLISGVHYIHSKGLVHRDLKLENLL--LDKNENLV-ITDFGFVNEFCSRNELM------- 207 Query: 678 KNLTGTARYASVSTHLGIE--QSRRDDMESLGYVLMYFLRGSLPW 806 K G+ YA+ + E ++R+ D+ S G +L L G LPW Sbjct: 208 KTSCGSPCYAAPELVISAEPYEARKADIWSCGVILYAILAGYLPW 252
>Q9H4B4:PLK3_HUMAN Serine/threonine-protein kinase PLK3 - Homo sapiens (Human)| Length = 646 Score = 63.2 bits (152), Expect = 4e-09 Identities = 57/218 (26%), Positives = 93/218 (42%), Gaps = 5/218 (2%) Frame = +3 Query: 171 EPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKL---ENVKTKH--PQLLYESKLY 335 +PR G Y GR LG G F Y T+ +T A+K+ V H ++L E +L+ Sbjct: 55 DPRSGRTYLKGRLLGKGGFARCYEATDTETGSAYAVKVIPQSRVAKPHQREKILNEIELH 114 Query: 336 RVLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRV 515 R LQ + F + + + SL ++ L V Q+++ + Sbjct: 115 RDLQHRHIVRFSHHFEDADNIYIFLELCSRKSLAHIWK-ARHTLLEPEVRYYLRQILSGL 173 Query: 516 EFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGT 695 +++H + LHRD+K NF + ++ + DFGLA + P + K + GT Sbjct: 174 KYLHQRGILHRDLKLGNFFI---TENMELKVGDFGLAARLEP-------PEQRKKTICGT 223 Query: 696 ARYASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQ 809 Y + L D+ SLG V+ L GS P++ Sbjct: 224 PNYVAPEVLLRQGHGPEADVWSLGCVMYTLLCGSPPFE 261
>Q9CEF5:PKNB_LACLA Probable serine/threonine-protein kinase pknB - Lactococcus lactis| subsp. lactis (Streptococcus lactis) Length = 627 Score = 63.2 bits (152), Expect = 4e-09 Identities = 50/217 (23%), Positives = 102/217 (47%), Gaps = 8/217 (3%) Frame = +3 Query: 186 NKYRLGRKLGSGSFGEIYLGTNVQTNEE-VAIKLENVKTKHPQLL---YESKLYRVLQGG 353 ++YR+ +++G G +Y G + + VAIK+ ++ + ++ + + + + Sbjct: 10 DRYRIIKEIGRGGMANVYQGEDTFLGDRLVAIKVLRSNFENDDIAIARFQREAFAMAELS 69 Query: 354 ----TGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEF 521 GIS+V F E +++ V G +L+ + N L+ + + ++++ ++ Sbjct: 70 HPNIVGISDVGEF--ESQQYIVMEFVDGMTLKQYINQ-NAPLANDEAIEIITEILSAMDM 126 Query: 522 IHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTAR 701 HS +HRD+KP N L+ + V + DFG+AK +TS Q + G+ Sbjct: 127 AHSHGIIHRDLKPQNVLV---SSSGTVKVTDFGIAKALSETSLTQ------TNTMFGSVH 177 Query: 702 YASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQG 812 Y S G + + D+ ++G +L L G +P+ G Sbjct: 178 YLSPEQARGSNATVQSDIYAIGIILFELLTGQIPFDG 214
>P06803:PIM1_MOUSE Proto-oncogene serine/threonine-protein kinase Pim-1 - Mus musculus| (Mouse) Length = 397 Score = 63.2 bits (152), Expect = 4e-09 Identities = 74/290 (25%), Positives = 122/290 (42%), Gaps = 15/290 (5%) Frame = +3 Query: 153 RARPPMEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK------------LENVK 296 + + P+E ++Y++G LGSG FG +Y G V N VAIK L N Sbjct: 113 KEKEPLE----SQYQVGPLLGSGGFGSVYSGIRVADNLPVAIKHVEKDRISDWGELPNGT 168 Query: 297 TKHPQLLYESKLYRVLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLK 476 +++ K+ G I + WF D VL+++ P ++DLF F + +L+ Sbjct: 169 RVPMEVVLLKKVSSDFSG--VIRLLDWF-ERPDSFVLILERPEP-VQDLFDFITERGALQ 224 Query: 477 TVLMLAD--QMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTST 650 L Q++ V H+ LHRDIK +N L+ L + ++ +IDFG +DT Sbjct: 225 EDLARGFFWQVLEAVRHCHNCGVLHRDIKDENILIDLSR--GEIKLIDFGSGALLKDT-- 280 Query: 651 HQHIPYRENKNLTGTARYASVS-THLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGT 827 + GT Y+ R + SLG +L + G +P++ + Sbjct: 281 -------VYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDEEII 333 Query: 828 KKQKYEKISERKIATSIEALCRGYPSEFQSFFHYCRSLRFEDSPDYQYLK 977 K Q + + + SE Q +C SLR D P ++ ++ Sbjct: 334 KGQVFFR--------------QTVSSECQHLIKWCLSLRPSDRPSFEEIR 369
>P06241:FYN_HUMAN Proto-oncogene tyrosine-protein kinase Fyn - Homo sapiens (Human)| Length = 537 Score = 63.2 bits (152), Expect = 4e-09 Identities = 66/278 (23%), Positives = 118/278 (42%), Gaps = 10/278 (3%) Frame = +3 Query: 195 RLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQ-LLYESKLYRVLQGGTGISNV 371 +L ++LG+G FGE+++GT N +VAIK T P+ L E+++ + L+ + Sbjct: 272 QLIKRLGNGQFGEVWMGT-WNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLY 330 Query: 372 KWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFLHRD 551 E Y V G L+ L R L L ++ +A Q+ + +I +++HRD Sbjct: 331 AVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRD 390 Query: 552 IKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVSTHLGI 731 ++ N L+G G + DFGLA+ D Y + ++ + L Sbjct: 391 LRSANILVGNGLICK---IADFGLARLIEDNE------YTARQGAKFPIKWTAPEAALYG 441 Query: 732 EQSRRDDMESLGYVLMYFL-RGSLPWQGLKAGTKKQKYEKISERKIATSIEALCRGY--- 899 + + D+ S G +L + +G +P+ G+ + R++ +E RGY Sbjct: 442 RFTIKSDVWSFGILLTELVTKGRVPYPGM------------NNREVLEQVE---RGYRMP 486 Query: 900 -----PSEFQSFFHYCRSLRFEDSPDYQYLKRLFRDLF 998 P +C E+ P ++YL+ D F Sbjct: 487 CPQDCPISLHELMIHCWKKDPEERPTFEYLQSFLEDYF 524
>P28547:CSK2A_THEPA Casein kinase II subunit alpha - Theileria parva| Length = 348 Score = 63.2 bits (152), Expect = 4e-09 Identities = 45/154 (29%), Positives = 80/154 (51%), Gaps = 2/154 (1%) Frame = +3 Query: 180 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK-LENVKTKHPQLLYESKLYRVLQGGT 356 V + Y + RK+G G F E++ G N T ++ IK L+ VK K ++ E K+ + L+GG Sbjct: 51 VPDSYEIVRKIGRGKFSEVFEGINTVTKDKCVIKILKPVKKK--KIKREIKILQNLRGGP 108 Query: 357 GISNVKWFGVEGDYNVLVMDVLGPSLEDL-FSFCNRKLSLKTVLMLADQMINRVEFIHSK 533 I +K + D ++ + + F LS++ + Q++ + + HS+ Sbjct: 109 NI--IKLLDIVKDPQSRTPSLIFEHVNNTDFKTLYPTLSIQDIKYYIYQLLKAMNYCHSQ 166 Query: 534 SFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKY 635 +HRDIKP N ++ K+ + +ID+GLA+ Y Sbjct: 167 GIMHRDIKPHNVMIDHEKKI--LRLIDWGLAEFY 198
>Q9Z265:CHK2_MOUSE Serine/threonine-protein kinase Chk2 - Mus musculus (Mouse)| Length = 546 Score = 63.2 bits (152), Expect = 4e-09 Identities = 66/253 (26%), Positives = 107/253 (42%), Gaps = 19/253 (7%) Frame = +3 Query: 186 NKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKT----------KHPQLLYESKLY 335 ++Y + + LGSG+ GE+ + +T ++VAIK+ + + P + E ++ Sbjct: 222 DEYIMSKTLGSGACGEVKMAFERKTCQKVAIKIISKRRFALGSSREADTAPSVETEIEIL 281 Query: 336 RVLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRV 515 + L I F E Y VL + G + + N++L T + QM+ V Sbjct: 282 KKLNHPCIIKIKDVFDAEDYYIVLELMEGGELFDRVVG--NKRLKEATCKLYFYQMLVAV 339 Query: 516 EFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGT 695 +++H +HRD+KP+N L+ + + + DFG +K +TS + L GT Sbjct: 340 QYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGQSKILGETSL--------MRTLCGT 391 Query: 696 ARYASVSTHLG---IEQSRRDDMESLGYVLMYFLRGSLPWQ------GLKAGTKKQKYEK 848 Y + + SR D SLG +L L G P+ LK KY Sbjct: 392 PTYLAPEVLVSNGTAGYSRAVDCWSLGVILFICLSGYPPFSEHKTQVSLKDQITSGKYNF 451 Query: 849 ISERKIATSIEAL 887 I E S EAL Sbjct: 452 IPEVWTDVSEEAL 464
>O15865:CDPK2_PLAFK Calcium-dependent protein kinase 2 - Plasmodium falciparum (isolate| K1 / Thailand) Length = 513 Score = 63.2 bits (152), Expect = 4e-09 Identities = 51/186 (27%), Positives = 87/186 (46%), Gaps = 22/186 (11%) Frame = +3 Query: 177 RVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK------LENV-----------KTKH 305 ++ +KY + KLG G++G +Y G + TN+ AIK L+N+ K H Sbjct: 67 KLEDKYIIDEKLGQGTYGCVYKGIDKVTNQLYAIKEEKKDRLKNINRFFQEIEIMKKLDH 126 Query: 306 PQLLYESKLYRVLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFC--NRKLSLKT 479 P ++ KLY + +Y L+M++ S +LF N + K Sbjct: 127 PNIV---KLYETYEND-------------NYIYLIMELC--SGRELFDSIIENGSFTEKN 168 Query: 480 VLMLADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKY---RDTST 650 + Q+ + + ++HS + +HRD+KP+NFL + + + +IDFGL+K T+T Sbjct: 169 AATIMKQIFSAIFYLHSLNIVHRDLKPENFLFQSENKDSLLKIIDFGLSKNLGTGEFTTT 228 Query: 651 HQHIPY 668 PY Sbjct: 229 KAGTPY 234
>Q8ICR0:CDPK2_PLAF7 Calcium-dependent protein kinase 2 - Plasmodium falciparum (isolate| 3D7) Length = 509 Score = 63.2 bits (152), Expect = 4e-09 Identities = 51/186 (27%), Positives = 87/186 (46%), Gaps = 22/186 (11%) Frame = +3 Query: 177 RVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK------LENV-----------KTKH 305 ++ +KY + KLG G++G +Y G + TN+ AIK L+N+ K H Sbjct: 67 KLEDKYIIDEKLGQGTYGCVYKGIDKVTNQLYAIKEEKKDRLKNINRFFQEIEIMKKLDH 126 Query: 306 PQLLYESKLYRVLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFC--NRKLSLKT 479 P ++ KLY + +Y L+M++ S +LF N + K Sbjct: 127 PNIV---KLYETYEND-------------NYIYLIMELC--SGRELFDSIIENGSFTEKN 168 Query: 480 VLMLADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKY---RDTST 650 + Q+ + + ++HS + +HRD+KP+NFL + + + +IDFGL+K T+T Sbjct: 169 AATIMKQIFSAIFYLHSLNIVHRDLKPENFLFQSENKDSLLKIIDFGLSKNLGTGEFTTT 228 Query: 651 HQHIPY 668 PY Sbjct: 229 KAGTPY 234
>Q8IWQ3:BRSK2_HUMAN BR serine/threonine-protein kinase 2 - Homo sapiens (Human)| Length = 736 Score = 63.2 bits (152), Expect = 4e-09 Identities = 59/209 (28%), Positives = 95/209 (45%), Gaps = 4/209 (1%) Frame = +3 Query: 192 YRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLEN-VKTKHPQLLYESKLYRVLQGGTGISN 368 YRL + LG G G + LG + T ++VAIK+ N K L+ + +L+ Sbjct: 19 YRLEKTLGKGQTGLVKLGVHCVTCQKVAIKIVNREKLSESVLMKVEREIAILKLIEHPHV 78 Query: 369 VKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRK--LSLKTVLMLADQMINRVEFIHSKSFL 542 +K V + L + + S +LF + +K L+ K Q+I+ ++F HS S Sbjct: 79 LKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSIC 138 Query: 543 HRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVSTH 722 HRD+KP+N L+ N + + DFG+A S + G+ YA Sbjct: 139 HRDLKPENLLL---DEKNNIRIADFGMASLQVGDSLLE--------TSCGSPHYACPEVI 187 Query: 723 LGIE-QSRRDDMESLGYVLMYFLRGSLPW 806 G + R+ D+ S G +L L G+LP+ Sbjct: 188 RGEKYDGRKADVWSCGVILFALLVGALPF 216
>O70405:ULK1_MOUSE Serine/threonine-protein kinase ULK1 - Mus musculus (Mouse)| Length = 1051 Score = 62.8 bits (151), Expect = 5e-09 Identities = 65/244 (26%), Positives = 105/244 (43%), Gaps = 17/244 (6%) Frame = +3 Query: 168 MEPRVGN-----KYRLGRK--LGSGSFGEIYLGTNVQTNE-EVAIKLENVKTKHPQLLYE 323 MEP G K+ RK +G G+F ++ G + + ++ EVA+K N K Sbjct: 1 MEPGRGGVETVGKFEFSRKDLIGHGAFAVVFKGRHREKHDLEVAVKCINKKNLAKSQTLL 60 Query: 324 SKLYRVLQGGTGISNVKWFGVEGDYN--VLVMDVL-GPSLEDLFSFCNRKLSLKTVLMLA 494 K ++L+ + V + + N LVM+ G L D + R LS TV + Sbjct: 61 GKEIKILKELKHENIVALYDFQEMANSVYLVMEYCNGGDLAD-YLHTMRTLSEDTVRLFL 119 Query: 495 DQMINRVEFIHSKSFLHRDIKPDNFLMGL--GKRAN----QVYMIDFGLAKKYRDTSTHQ 656 Q+ + +HSK +HRD+KP N L+ G+RAN +V + DFG A+ + Sbjct: 120 QQIAGAMRLLHSKGIIHRDLKPQNILLSNPGGRRANPSNIRVKIADFGFARYLQSNMM-- 177 Query: 657 HIPYRENKNLTGTARYASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQ 836 L G+ Y + + + D+ S+G ++ L G P+Q + Sbjct: 178 ------AATLCGSPMYMAPEVIMSQHYDGKADLWSIGTIVYQCLTGKAPFQASSPQDLRL 231 Query: 837 KYEK 848 YEK Sbjct: 232 FYEK 235
>Q9UEE5:ST17A_HUMAN Serine/threonine-protein kinase 17A - Homo sapiens (Human)| Length = 414 Score = 62.8 bits (151), Expect = 5e-09 Identities = 68/297 (22%), Positives = 118/297 (39%), Gaps = 11/297 (3%) Frame = +3 Query: 24 EYPQSHTSIPAQTLATNLRNSSLA---QVPP*LDALNLGGGSVACVRARPPMEPRVGNKY 194 E P S S P T + L+ + PP A L A VR P + G Sbjct: 5 EKPGSGGSSPGATSGSGRAGRGLSGPCRPPPPPQARGLLTEIRAVVRTEPFQD---GYSL 61 Query: 195 RLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTK----HPQLLYESKLYRVLQGGTGI 362 GR+LG G F + + +E A K + K ++++E + + Q + Sbjct: 62 CPGRELGRGKFAVVRKCIKKDSGKEFAAKFMRKRRKGQDCRMEIIHEIAVLELAQDNPWV 121 Query: 363 SNVKWFGVEGDYNVLVMDVLGPSLEDLFSFC----NRKLSLKTVLMLADQMINRVEFIHS 530 N+ +LV++ ++F C K V L Q++ V F+H+ Sbjct: 122 INLHEVYETASEMILVLEYAAGG--EIFDQCVADREEAFKEKDVQRLMRQILEGVHFLHT 179 Query: 531 KSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYAS 710 + +H D+KP N L+ + ++DFGL++ +++ E + + GT Y + Sbjct: 180 RDVVHLDLKPQNILLTSESPLGDIKIVDFGLSRILKNS--------EELREIMGTPEYVA 231 Query: 711 VSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKISERKIATSIE 881 S DM S+G + L G P+ G K++ + IS+ ++ S E Sbjct: 232 PEILSYDPISMATDMWSIGVLTYVMLTGISPFLG---NDKQETFLNISQMNLSYSEE 285
>Q9Z335:SBK1_RAT Serine/threonine-protein kinase SBK1 - Rattus norvegicus (Rat)| Length = 417 Score = 62.8 bits (151), Expect = 5e-09 Identities = 57/215 (26%), Positives = 94/215 (43%), Gaps = 5/215 (2%) Frame = +3 Query: 180 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENV-KTKHPQLLYESKLYRVLQGGT 356 V Y L R+LG G++G++ L T ++A+K N KTK L E + L Sbjct: 49 VTKHYELVRELGKGTYGKVDLVAYKGTGTKMALKFVNKSKTKLKNFLREVSITNSLSSSP 108 Query: 357 GISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLK--TVLMLADQMINRVEFIHS 530 I V E + + P+ DLF ++ L TV Q+ ++F+HS Sbjct: 109 FIIKVFDVVFETEECYVFAQEYAPA-GDLFDIIPPQVGLPEDTVKRCVQQLGLALDFMHS 167 Query: 531 KSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKY--RDTSTHQHIPYRENKNLTGTARY 704 + +HRDIKP+N L+ + +V + DFG+ ++ R IPY + R Sbjct: 168 RQLVHRDIKPENVLL-FDRECRRVKLADFGMTRRVGCRVKRVSGTIPYTA-PEVCQAGRA 225 Query: 705 ASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQ 809 + G+ D+ + G ++ L G+ PW+ Sbjct: 226 DGFAVDTGV------DVWAFGVLIFCVLTGNFPWE 254
>Q8QZX0:SBK1_MOUSE Serine/threonine-protein kinase SBK1 - Mus musculus (Mouse)| Length = 417 Score = 62.8 bits (151), Expect = 5e-09 Identities = 57/215 (26%), Positives = 94/215 (43%), Gaps = 5/215 (2%) Frame = +3 Query: 180 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENV-KTKHPQLLYESKLYRVLQGGT 356 V Y L R+LG G++G++ L T ++A+K N KTK L E + L Sbjct: 49 VTKHYELVRELGKGTYGKVDLVAYKGTGTKMALKFVNKSKTKLKNFLREVSITNSLSSSP 108 Query: 357 GISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLK--TVLMLADQMINRVEFIHS 530 I V E + + P+ DLF ++ L TV Q+ ++F+HS Sbjct: 109 FIIKVFDVVFETEECYVFAQEYAPA-GDLFDIIPPQVGLPEDTVKRCVQQLGLALDFMHS 167 Query: 531 KSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKY--RDTSTHQHIPYRENKNLTGTARY 704 + +HRDIKP+N L+ + +V + DFG+ ++ R IPY + R Sbjct: 168 RQLVHRDIKPENVLL-FDRECRRVKLADFGMTRRVGCRVKRVSGTIPYTA-PEVCQAGRA 225 Query: 705 ASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQ 809 + G+ D+ + G ++ L G+ PW+ Sbjct: 226 DGFAVDTGV------DVWAFGVLIFCVLTGNFPWE 254
>Q5L5J7:PKND_CHLAB Serine/threonine-protein kinase pknD - Chlamydophila abortus| Length = 933 Score = 62.8 bits (151), Expect = 5e-09 Identities = 63/236 (26%), Positives = 107/236 (45%), Gaps = 27/236 (11%) Frame = +3 Query: 192 YRLGRKLGSGSFGEIYLGTNVQTNEEVAIK-----LENVKTKHPQLLYESKLYRVLQGGT 356 Y + R +G G GE+YL + + +VA+K L + + + L E+K+ L Sbjct: 4 YDIIRMIGKGGMGEVYLAYDPICSRKVALKRIREDLSDNELLKKRFLREAKIAADLVH-P 62 Query: 357 GISNVKWFGVEGDYNVLVMDVL-GPSLEDLFSF---CN-------RKLSLKTVLMLADQM 503 G+ V + D M + G +L+ L C+ + S+ T L + ++ Sbjct: 63 GVVPVFTICSDSDLVYYTMPYIEGYTLKSLLKSVWQCDSLPKDLAEQTSVGTFLSIFHKI 122 Query: 504 INRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLA---KKYRDTSTHQHIPYRE 674 + +E++HS+ LHRD+KPDN L+GL ++V ++D+G A + D IP Sbjct: 123 CSTIEYVHSRGILHRDLKPDNILLGL---FSEVVILDWGAALSKEMKEDVLLDLDIPMPG 179 Query: 675 N--KNLT------GTARYASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLK 818 + N+T GT Y + G S D+ +LG +L L S P++ K Sbjct: 180 SMFSNMTVPGKIVGTPDYMAPERLRGAPASESTDIYALGVILYQMLTLSFPYRNKK 235
>P11309:PIM1_HUMAN Proto-oncogene serine/threonine-protein kinase Pim-1 - Homo sapiens| (Human) Length = 404 Score = 62.8 bits (151), Expect = 5e-09 Identities = 73/290 (25%), Positives = 124/290 (42%), Gaps = 15/290 (5%) Frame = +3 Query: 153 RARPPMEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK------------LENVK 296 + + P+E ++Y++G LGSG FG +Y G V N VAIK L N Sbjct: 120 KEKEPLE----SQYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISDWGELPN-G 174 Query: 297 TKHPQLLYESKLYRVLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLK 476 T+ P + L +V G +G+ + + D VL+++ P ++DLF F + +L+ Sbjct: 175 TRVPMEVV--LLKKVSSGFSGVIRLLDWFERPDSFVLILERPEP-VQDLFDFITERGALQ 231 Query: 477 TVLMLAD--QMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTST 650 L + Q++ V H+ LHRDIK +N L+ L + ++ +IDFG +DT Sbjct: 232 EELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNR--GELKLIDFGSGALLKDT-- 287 Query: 651 HQHIPYRENKNLTGTARYASVS-THLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGT 827 + GT Y+ R + SLG +L + G +P++ Sbjct: 288 -------VYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFE------ 334 Query: 828 KKQKYEKISERKIATSIEALCRGYPSEFQSFFHYCRSLRFEDSPDYQYLK 977 + +I + SE Q +C +LR D P ++ ++ Sbjct: 335 --------HDEEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQ 376
>Q95LJ0:PIM1_FELCA Proto-oncogene serine/threonine-protein kinase pim-1 - Felis| silvestris catus (Cat) Length = 313 Score = 62.8 bits (151), Expect = 5e-09 Identities = 73/290 (25%), Positives = 124/290 (42%), Gaps = 15/290 (5%) Frame = +3 Query: 153 RARPPMEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK------------LENVK 296 + + P+E ++Y++G LGSG FG +Y G V N VAIK L N Sbjct: 29 KEKEPLE----SQYQVGPLLGSGGFGSVYSGIRVADNLPVAIKHVEKDRISDWGELPN-G 83 Query: 297 TKHPQLLYESKLYRVLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLK 476 T+ P + L +V G +G+ + + D VL+++ P ++DLF F + +L+ Sbjct: 84 TRVPMEVV--LLKKVSSGFSGVIRLLDWFERPDSFVLILERPEP-VQDLFDFITERGALQ 140 Query: 477 TVLMLAD--QMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTST 650 L + Q++ V H+ LHRDIK +N L+ L + ++ +IDFG +DT Sbjct: 141 EELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNR--GELKLIDFGSGALLKDT-- 196 Query: 651 HQHIPYRENKNLTGTARYASVS-THLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGT 827 + GT Y+ R + SLG +L + G +P++ Sbjct: 197 -------VYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFE------ 243 Query: 828 KKQKYEKISERKIATSIEALCRGYPSEFQSFFHYCRSLRFEDSPDYQYLK 977 + +I + SE Q +C +LR D P ++ ++ Sbjct: 244 --------HDEEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRPSFEEIQ 285
>P25323:MYLK_DICDI Myosin light chain kinase - Dictyostelium discoideum (Slime mold)| Length = 295 Score = 62.8 bits (151), Expect = 5e-09 Identities = 58/226 (25%), Positives = 94/226 (41%), Gaps = 4/226 (1%) Frame = +3 Query: 192 YRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENV----KTKHPQLLYESKLYRVLQGGTG 359 Y +LG G+F +YLG N QT + AIK+ N K L E + + + Sbjct: 8 YEFKEELGRGAFSIVYLGENKQTKQRYAIKVINKSELGKDYEKNLKMEVDILKKVNHPNI 67 Query: 360 ISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSF 539 I+ + F +++ V G L D S L ++++ V ++H + Sbjct: 68 IALKELFDTPEKLYLVMELVTGGELFDKIVE-KGSYSEADAANLVKKIVSAVGYLHGLNI 126 Query: 540 LHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVST 719 +HRD+KP+N L+ + +V + DFGL+K T Q GT Y + Sbjct: 127 VHRDLKPENLLLKSKENHLEVAIADFGLSKIIGQTLVMQ--------TACGTPSYVAPEV 178 Query: 720 HLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKISE 857 + DM S+G + L G P+ G T + +E+I E Sbjct: 179 LNATGYDKEVDMWSIGVITYILLCGFPPFYG---DTVPEIFEQIME 221
>P41279:M3K8_HUMAN Mitogen-activated protein kinase kinase kinase 8 - Homo sapiens| (Human) Length = 467 Score = 62.8 bits (151), Expect = 5e-09 Identities = 54/207 (26%), Positives = 94/207 (45%), Gaps = 6/207 (2%) Frame = +3 Query: 204 RKLGS-----GSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTGISN 368 R +GS G+FG++YL +++T + +A KL V P + +R Sbjct: 137 RNIGSDFIPRGAFGKVYLAQDIKTKKRMACKLIPVDQFKPSDVEIQACFRHENIAELYGA 196 Query: 369 VKWFGVEGDYNVLVMDV-LGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFLH 545 V W G+ L M+ G S+ + C + ++ + ++ ++F+HSK +H Sbjct: 197 VLW----GETVHLFMEAGEGGSVLEKLESCGPMREFE-IIWVTKHVLKGLDFLHSKKVIH 251 Query: 546 RDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVSTHL 725 DIKP N + + + ++DFGL+ + + + P K+L GT Y S L Sbjct: 252 HDIKPSNIVF----MSTKAVLVDFGLSVQMTE---DVYFP----KDLRGTEIYMSPEVIL 300 Query: 726 GIEQSRRDDMESLGYVLMYFLRGSLPW 806 S + D+ SLG L++ G+ PW Sbjct: 301 CRGHSTKADIYSLGATLIHMQTGTPPW 327
>Q62101:KPCD1_MOUSE Serine/threonine-protein kinase D1 - Mus musculus (Mouse)| Length = 918 Score = 62.8 bits (151), Expect = 5e-09 Identities = 57/205 (27%), Positives = 95/205 (46%), Gaps = 6/205 (2%) Frame = +3 Query: 210 LGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHP-----QLLYESKLYRVLQGGTGISNVK 374 LGSG FG +Y G + +T +VAIK+ + K + P QL E + + L G+ N++ Sbjct: 595 LGSGQFGIVYGGKHRKTGRDVAIKIID-KLRFPTKQESQLRNEVAILQNLHH-PGVVNLE 652 Query: 375 WFGVEGDYNVLVMDVL-GPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFLHRD 551 + +VM+ L G LE + S L L Q++ + +H K+ +H D Sbjct: 653 CMFETPERVFVVMEKLHGDMLEMILSSEKGWLPEHITKFLITQILVALRHLHFKNIVHCD 712 Query: 552 IKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVSTHLGI 731 +KP+N L+ QV + DFG A+ + S +++ GT Y + Sbjct: 713 LKPENVLLASADPFPQVKLCDFGFARIIGEKSF--------RRSVVGTPAYLAPEVLRNK 764 Query: 732 EQSRRDDMESLGYVLMYFLRGSLPW 806 +R DM S+G ++ L G+ P+ Sbjct: 765 GYNRSLDMWSVGVIIYVSLSGTFPF 789
>Q62844:FYN_RAT Proto-oncogene tyrosine-protein kinase Fyn - Rattus norvegicus (Rat)| Length = 537 Score = 62.8 bits (151), Expect = 5e-09 Identities = 66/278 (23%), Positives = 118/278 (42%), Gaps = 10/278 (3%) Frame = +3 Query: 195 RLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQ-LLYESKLYRVLQGGTGISNV 371 +L ++LG+G FGE+++GT N +VAIK T P+ L E+++ + L+ + Sbjct: 272 QLIKRLGNGQFGEVWMGT-WNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLY 330 Query: 372 KWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFLHRD 551 E Y V G L+ L R L L ++ +A Q+ + +I +++HRD Sbjct: 331 AVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRD 390 Query: 552 IKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVSTHLGI 731 ++ N L+G G + DFGLA+ D Y + ++ + L Sbjct: 391 LRSANILVGNGLICK---IADFGLARLIEDNE------YTARQGAKFPIKWTAPEAALYG 441 Query: 732 EQSRRDDMESLGYVLMYFL-RGSLPWQGLKAGTKKQKYEKISERKIATSIEALCRGY--- 899 + + D+ S G +L + +G +P+ G+ + R++ +E RGY Sbjct: 442 RFTIKSDVWSFGILLTELVTKGRVPYPGM------------NNREVLEQVE---RGYRMP 486 Query: 900 -----PSEFQSFFHYCRSLRFEDSPDYQYLKRLFRDLF 998 P +C E+ P ++YL+ D F Sbjct: 487 CPQDCPISLHELMIHCWKKDPEERPTFEYLQGFLEDYF 524
>A1Y2K1:FYN_PIG Proto-oncogene tyrosine-protein kinase Fyn - Sus scrofa (Pig)| Length = 537 Score = 62.8 bits (151), Expect = 5e-09 Identities = 66/278 (23%), Positives = 118/278 (42%), Gaps = 10/278 (3%) Frame = +3 Query: 195 RLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQ-LLYESKLYRVLQGGTGISNV 371 +L ++LG+G FGE+++GT N +VAIK T P+ L E+++ + L+ + Sbjct: 272 QLIKRLGNGQFGEVWMGT-WNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLY 330 Query: 372 KWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFLHRD 551 E Y V G L+ L R L L ++ +A Q+ + +I +++HRD Sbjct: 331 AVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRD 390 Query: 552 IKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVSTHLGI 731 ++ N L+G G + DFGLA+ D Y + ++ + L Sbjct: 391 LRSANILVGNGLICK---IADFGLARLIEDNE------YTARQGAKFPIKWTAPEAALYG 441 Query: 732 EQSRRDDMESLGYVLMYFL-RGSLPWQGLKAGTKKQKYEKISERKIATSIEALCRGY--- 899 + + D+ S G +L + +G +P+ G+ + R++ +E RGY Sbjct: 442 RFTIKSDVWSFGILLTELVTKGRVPYPGM------------NNREVLEQVE---RGYRMP 486 Query: 900 -----PSEFQSFFHYCRSLRFEDSPDYQYLKRLFRDLF 998 P +C E+ P ++YL+ D F Sbjct: 487 CPQDCPISLHELMIHCWKKDPEERPTFEYLQGFLEDYF 524
>A0JNB0:FYN_BOVIN Proto-oncogene tyrosine-protein kinase Fyn - Bos taurus (Bovine)| Length = 537 Score = 62.8 bits (151), Expect = 5e-09 Identities = 66/278 (23%), Positives = 118/278 (42%), Gaps = 10/278 (3%) Frame = +3 Query: 195 RLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQ-LLYESKLYRVLQGGTGISNV 371 +L ++LG+G FGE+++GT N +VAIK T P+ L E+++ + L+ + Sbjct: 272 QLIKRLGNGQFGEVWMGT-WNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLY 330 Query: 372 KWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFLHRD 551 E Y V G L+ L R L L ++ +A Q+ + +I +++HRD Sbjct: 331 AVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRD 390 Query: 552 IKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVSTHLGI 731 ++ N L+G G + DFGLA+ D Y + ++ + L Sbjct: 391 LRSANILVGNGLICK---IADFGLARLIEDNE------YTARQGAKFPIKWTAPEAALYG 441 Query: 732 EQSRRDDMESLGYVLMYFL-RGSLPWQGLKAGTKKQKYEKISERKIATSIEALCRGY--- 899 + + D+ S G +L + +G +P+ G+ + R++ +E RGY Sbjct: 442 RFTIKSDVWSFGILLTELVTKGRVPYPGM------------NNREVLEQVE---RGYRMP 486 Query: 900 -----PSEFQSFFHYCRSLRFEDSPDYQYLKRLFRDLF 998 P +C E+ P ++YL+ D F Sbjct: 487 CPQDCPISLHELMIHCWKKDPEERPTFEYLQGFLEDYF 524
>Q69Z98:BRSK2_MOUSE BR serine/threonine-protein kinase 2 - Mus musculus (Mouse)| Length = 735 Score = 62.8 bits (151), Expect = 5e-09 Identities = 59/209 (28%), Positives = 95/209 (45%), Gaps = 4/209 (1%) Frame = +3 Query: 192 YRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLEN-VKTKHPQLLYESKLYRVLQGGTGISN 368 YRL + LG G G + LG + T ++VAIK+ N K L+ + +L+ Sbjct: 20 YRLEKTLGKGQTGLVKLGIHCVTCQKVAIKIVNREKLSESVLMKVEREIAILKLIEHPHV 79 Query: 369 VKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRK--LSLKTVLMLADQMINRVEFIHSKSFL 542 +K V + L + + S +LF + +K L+ K Q+I+ ++F HS S Sbjct: 80 LKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSIC 139 Query: 543 HRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVSTH 722 HRD+KP+N L+ N + + DFG+A S + G+ YA Sbjct: 140 HRDLKPENLLL---DERNNIRIADFGMASLQVGDSLLE--------TSCGSPHYACPEVI 188 Query: 723 LGIE-QSRRDDMESLGYVLMYFLRGSLPW 806 G + R+ D+ S G +L L G+LP+ Sbjct: 189 RGEKYDGRKADVWSCGVILFALLVGALPF 217
>P45894:AAPK1_CAEEL 5'-AMP-activated protein kinase catalytic subunit alpha-1 -| Caenorhabditis elegans Length = 589 Score = 62.8 bits (151), Expect = 5e-09 Identities = 61/235 (25%), Positives = 104/235 (44%), Gaps = 25/235 (10%) Frame = +3 Query: 177 RVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLEN--------------------VK 296 ++GN + + +G G+FG + GT++QT +VAIK+ N K Sbjct: 20 KIGN-FVIKETIGKGAFGAVKRGTHIQTGYDVAIKILNRGRMKGLGTVNKTRNEIDNLQK 78 Query: 297 TKHPQLLYESKLYRVLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRK--LS 470 HP + ++L+RV+ + I LVM+++ +LFS+ RK L Sbjct: 79 LTHPHI---TRLFRVISTPSDI-------------FLVMELVSGG--ELFSYITRKGALP 120 Query: 471 LKTVLMLADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTST 650 ++ Q+I+ V + H+ +HRD+KP+N L+ K + + DFGL+ D Sbjct: 121 IRESRRYFQQIISGVSYCHNHMIVHRDLKPENLLLDANK---NIKIADFGLSNYMTDGDL 177 Query: 651 HQHIPYRENKNLTGTARYAS---VSTHLGIEQSRRDDMESLGYVLMYFLRGSLPW 806 G+ YA+ +S L + D+ S G +L L G+LP+ Sbjct: 178 --------LSTACGSPNYAAPELISNKLYV--GPEVDLWSCGVILYAMLCGTLPF 222
>Q91820:STK6_XENLA Serine/threonine-protein kinase 6 - Xenopus laevis (African clawed| frog) Length = 407 Score = 62.4 bits (150), Expect = 6e-09 Identities = 58/228 (25%), Positives = 96/228 (42%), Gaps = 6/228 (2%) Frame = +3 Query: 192 YRLGRKLGSGSFGEIYLGTNVQTNEEVAIK------LENVKTKHPQLLYESKLYRVLQGG 353 + +GR LG G FG +YL ++ +A+K LE +H QL E ++ L+ Sbjct: 140 FEIGRPLGKGKFGNVYLARERESKFILALKVLFKSQLEKAGVEH-QLRREVEIQSHLRHP 198 Query: 354 TGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSK 533 + +F +++ G L C R ++ + + Q+ + + HSK Sbjct: 199 NILRLYGYFHDASRVYLILDYAPGGELFRELQKCTRFDDQRSAMYIK-QLAEALLYCHSK 257 Query: 534 SFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASV 713 +HRDIKP+N L+G ++ + DFG + H P L GT Y Sbjct: 258 KVIHRDIKPENLLLGSN---GELKIADFGWS---------VHAPSSRRTTLCGTLDYLPP 305 Query: 714 STHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKISE 857 G D+ SLG + FL G P++ T ++ Y +IS+ Sbjct: 306 EMIEGRMHDETVDLWSLGVLCYEFLVGKPPFE---TDTHQETYRRISK 350
>Q9N0P9:PIM1_BOVIN Proto-oncogene serine/threonine-protein kinase pim-1 - Bos taurus| (Bovine) Length = 313 Score = 62.4 bits (150), Expect = 6e-09 Identities = 73/290 (25%), Positives = 123/290 (42%), Gaps = 15/290 (5%) Frame = +3 Query: 153 RARPPMEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK------------LENVK 296 + + P+E ++Y++G LGSG FG +Y G V N VAIK L N Sbjct: 29 KEKEPLE----SQYQVGPLLGSGGFGSVYSGIRVADNLPVAIKHVEKDRISDWGELPN-G 83 Query: 297 TKHPQLLYESKLYRVLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLK 476 T+ P + L +V G +G+ + + D VL+++ P ++DLF F + +L+ Sbjct: 84 TRVPMEVV--LLKKVSSGFSGVIRLLDWFERPDSFVLILERPEP-VQDLFDFITERGALQ 140 Query: 477 TVLMLAD--QMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTST 650 L + Q++ V H LHRDIK +N L+ L + ++ +IDFG +DT Sbjct: 141 EELARSFFWQVLEAVRHCHDCGVLHRDIKDENILIDLNR--GELKLIDFGSGALLKDT-- 196 Query: 651 HQHIPYRENKNLTGTARYASVS-THLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGT 827 + GT Y+ R + SLG +L + G +P++ Sbjct: 197 -------VYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFE------ 243 Query: 828 KKQKYEKISERKIATSIEALCRGYPSEFQSFFHYCRSLRFEDSPDYQYLK 977 + +I + SE Q +C +LR D P ++ ++ Sbjct: 244 --------HDEEIVRGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQ 285
>P35465:PAK1_RAT Serine/threonine-protein kinase PAK 1 - Rattus norvegicus (Rat)| Length = 544 Score = 62.4 bits (150), Expect = 6e-09 Identities = 52/208 (25%), Positives = 94/208 (45%), Gaps = 2/208 (0%) Frame = +3 Query: 189 KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQG-GTGIS 365 KY K+G G+ G +Y +V T +EVAIK N++ + + L +++ + + I Sbjct: 268 KYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIV 327 Query: 366 NVKWFGVEGDYNVLVMDVL-GPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFL 542 N + GD +VM+ L G SL D+ + + + + + + +EF+HS + Sbjct: 328 NYLDSYLVGDELWVVMEYLAGGSLTDVVT--ETCMDEGQIAAVCRECLQALEFLHSNQVI 385 Query: 543 HRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVSTH 722 HRDIK DN L+G+ V + DFG + + + + GT + + Sbjct: 386 HRDIKSDNILLGMD---GSVKLTDFGFCAQITPEQS-------KRSTMVGTPYWMAPEVV 435 Query: 723 LGIEQSRRDDMESLGYVLMYFLRGSLPW 806 + D+ SLG + + + G P+ Sbjct: 436 TRKAYGPKVDIWSLGIMAIEMIEGEPPY 463
>Q13153:PAK1_HUMAN Serine/threonine-protein kinase PAK 1 - Homo sapiens (Human)| Length = 545 Score = 62.4 bits (150), Expect = 6e-09 Identities = 52/208 (25%), Positives = 94/208 (45%), Gaps = 2/208 (0%) Frame = +3 Query: 189 KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQG-GTGIS 365 KY K+G G+ G +Y +V T +EVAIK N++ + + L +++ + + I Sbjct: 269 KYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIV 328 Query: 366 NVKWFGVEGDYNVLVMDVL-GPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFL 542 N + GD +VM+ L G SL D+ + + + + + + +EF+HS + Sbjct: 329 NYLDSYLVGDELWVVMEYLAGGSLTDVVT--ETCMDEGQIAAVCRECLQALEFLHSNQVI 386 Query: 543 HRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVSTH 722 HRDIK DN L+G+ V + DFG + + + + GT + + Sbjct: 387 HRDIKSDNILLGMD---GSVKLTDFGFCAQITPEQS-------KRSTMVGTPYWMAPEVV 436 Query: 723 LGIEQSRRDDMESLGYVLMYFLRGSLPW 806 + D+ SLG + + + G P+ Sbjct: 437 TRKAYGPKVDIWSLGIMAIEMIEGEPPY 464
>Q08E52:PAK1_BOVIN Serine/threonine-protein kinase PAK 1 - Bos taurus (Bovine)| Length = 544 Score = 62.4 bits (150), Expect = 6e-09 Identities = 52/208 (25%), Positives = 94/208 (45%), Gaps = 2/208 (0%) Frame = +3 Query: 189 KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQG-GTGIS 365 KY K+G G+ G +Y +V T +EVAIK N++ + + L +++ + + I Sbjct: 268 KYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIV 327 Query: 366 NVKWFGVEGDYNVLVMDVL-GPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFL 542 N + GD +VM+ L G SL D+ + + + + + + +EF+HS + Sbjct: 328 NYLDSYLVGDELWVVMEYLAGGSLTDVVT--ETCMDEGQIAAVCRECLQALEFLHSNQVI 385 Query: 543 HRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVSTH 722 HRDIK DN L+G+ V + DFG + + + + GT + + Sbjct: 386 HRDIKSDNILLGMD---GSVKLTDFGFCAQITPEQS-------KRSTMVGTPYWMAPEVV 435 Query: 723 LGIEQSRRDDMESLGYVLMYFLRGSLPW 806 + D+ SLG + + + G P+ Sbjct: 436 TRKAYGPKVDIWSLGIMAIEMIEGEPPY 463
>P13406:FYN_XENLA Proto-oncogene tyrosine-protein kinase Fyn - Xenopus laevis (African| clawed frog) Length = 537 Score = 62.4 bits (150), Expect = 6e-09 Identities = 66/278 (23%), Positives = 117/278 (42%), Gaps = 10/278 (3%) Frame = +3 Query: 195 RLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQ-LLYESKLYRVLQGGTGISNV 371 +L ++LG+G FGE+++GT N +VAIK T P+ L E+++ + L+ + Sbjct: 272 QLIKRLGNGQFGEVWMGT-WNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLY 330 Query: 372 KWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFLHRD 551 E Y V G L+ L R L L ++ +A Q+ + +I +++HRD Sbjct: 331 AVVSEEPIYIVTEYMSKGSLLDFLKDGEGRALKLPNLVDMAAQVARGMAYIERMNYIHRD 390 Query: 552 IKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVSTHLGI 731 ++ N L+G G + DFGLA+ D Y + ++ + L Sbjct: 391 LRSANILVGNGLICK---IADFGLARLIEDNE------YTARQGAKFPIKWTAPEAALYG 441 Query: 732 EQSRRDDMESLGYVLMYFL-RGSLPWQGLKAGTKKQKYEKISERKIATSIEALCRGY--- 899 + + D+ S G +L + +G +P+ G+ + R++ +E RGY Sbjct: 442 RFTIKSDVWSFGILLTELVTKGRVPYPGM------------NNREVLEQVE---RGYRMP 486 Query: 900 -----PSEFQSFFHYCRSLRFEDSPDYQYLKRLFRDLF 998 P C E+ P ++YL+ D F Sbjct: 487 CPQDCPISLHELMLNCWKKDPEERPTFEYLQGFLEDYF 524
>Q6DE87:CHK1_XENLA Serine/threonine-protein kinase Chk1 - Xenopus laevis (African| clawed frog) Length = 474 Score = 62.4 bits (150), Expect = 6e-09 Identities = 57/212 (26%), Positives = 97/212 (45%), Gaps = 9/212 (4%) Frame = +3 Query: 198 LGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKH--PQLLYESKLYRVLQGGTGISNV 371 L + LG G++GE+ L N +T E VA+K+ ++ P+ + + + T I V Sbjct: 11 LVQTLGEGAYGEVQLAVNRKTEEAVAVKIVDMTRAADCPENIKKEICINRMLSHTNI--V 68 Query: 372 KWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSL--KTVLMLADQMINRVEFIHSKSFLH 545 +++G + N+ + + +LF + + + Q+I VE++HS H Sbjct: 69 RFYGHRREGNIQYLFLEYCRGGELFDRIEPDVGMPEQDAQKFFQQLIAGVEYLHSIGITH 128 Query: 546 RDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVSTHL 725 RDIKP+N L+ +Q+ + DFGLA +R + + + GT Y + Sbjct: 129 RDIKPENLLL---DERDQLKISDFGLATVFRHNGKERLL-----NKMCGTLPYVAPE--- 177 Query: 726 GIEQSRR-----DDMESLGYVLMYFLRGSLPW 806 + +SR D+ S G VL L G LPW Sbjct: 178 -LIKSRAFHADPVDVWSCGIVLTAMLAGELPW 208
>Q925K9:TSSK6_MOUSE Testis-specific serine/threonine-protein kinase 6 - Mus musculus| (Mouse) Length = 273 Score = 62.0 bits (149), Expect = 8e-09 Identities = 57/213 (26%), Positives = 97/213 (45%), Gaps = 8/213 (3%) Frame = +3 Query: 192 YRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLL--YESKLYRVLQGGTGIS 365 Y+LGR +G GS+ ++ + T+ + VAIK+ + + P + + + +L+G Sbjct: 12 YKLGRTIGEGSYSKVKVATSKKYKGTVAIKVVDRRRAPPDFVNKFLPRELSILRGVRHPH 71 Query: 366 NVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNR--KLSLKTVLMLADQMINRVEFIHSKSF 539 V F N + V+ + DL R ++ L Q+ V ++H Sbjct: 72 IVHVFEFIEVCNGKLYIVMEAAATDLLQAVQRNGRIPGSQARELFSQIAGAVRYLHDHHL 131 Query: 540 LHRDIKPDNFLMGLGKRANQVYMIDFGLAKK---YRDTSTHQHIPYRENKNLTGTARYAS 710 +HRD+K +N L+ +R +V + DFG ++ Y D ST G+A YAS Sbjct: 132 VHRDLKCENVLLSPDER--RVKITDFGFGRQAHGYPDLST----------TYCGSAAYAS 179 Query: 711 VSTHLGIE-QSRRDDMESLGYVLMYFLRGSLPW 806 LGI ++ D+ SLG VL + G +P+ Sbjct: 180 PEVLLGIPYDPKKYDVWSLGVVLYVMVTGCMPF 212
>O88643:PAK1_MOUSE Serine/threonine-protein kinase PAK 1 - Mus musculus (Mouse)| Length = 545 Score = 62.0 bits (149), Expect = 8e-09 Identities = 52/208 (25%), Positives = 94/208 (45%), Gaps = 2/208 (0%) Frame = +3 Query: 189 KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQG-GTGIS 365 KY K+G G+ G +Y +V T +EVAIK N++ + + L +++ + + I Sbjct: 269 KYTPFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIV 328 Query: 366 NVKWFGVEGDYNVLVMDVL-GPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFL 542 N + GD +VM+ L G SL D+ + + + + + + +EF+HS + Sbjct: 329 NYLDSYLVGDELWVVMEYLAGGSLTDVVT--ETCMDEGQIAAVCRECLQALEFLHSNQVI 386 Query: 543 HRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVSTH 722 HRDIK DN L+G+ V + DFG + + + + GT + + Sbjct: 387 HRDIKSDNILLGMD---GSVKLTDFGFCAQITPEQS-------KRSTMVGTPYWMAPEVV 436 Query: 723 LGIEQSRRDDMESLGYVLMYFLRGSLPW 806 + D+ SLG + + + G P+ Sbjct: 437 TRKAYGPKVDIWSLGIMAIEMIEGEPPY 464
>Q7KZI7:MARK2_HUMAN Serine/threonine-protein kinase MARK2 - Homo sapiens (Human)| Length = 788 Score = 62.0 bits (149), Expect = 8e-09 Identities = 52/218 (23%), Positives = 103/218 (47%), Gaps = 4/218 (1%) Frame = +3 Query: 171 EPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK-LENVKTKHPQLLYESKLYRVLQ 347 +P +GN YRL + +G G+F ++ L ++ T +EVA+K ++ + L + R+++ Sbjct: 47 QPHIGN-YRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMK 105 Query: 348 GGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSF--CNRKLSLKTVLMLADQMINRVEF 521 + VK F V L + + S ++F + + ++ K Q+++ V++ Sbjct: 106 VLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQY 165 Query: 522 IHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTAR 701 H K +HRD+K +N L+ + + DFG + ++ + + G+ Sbjct: 166 CHQKFIVHRDLKAENLLLDADM---NIKIADFGFSNEFTFGN--------KLDTFCGSPP 214 Query: 702 YASVSTHLGIEQSRRD-DMESLGYVLMYFLRGSLPWQG 812 YA+ G + + D+ SLG +L + GSLP+ G Sbjct: 215 YAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDG 252
>Q38997:KIN10_ARATH SNF1-related protein kinase catalytic subunit alpha KIN10 -| Arabidopsis thaliana (Mouse-ear cress) Length = 535 Score = 62.0 bits (149), Expect = 8e-09 Identities = 64/228 (28%), Positives = 96/228 (42%), Gaps = 23/228 (10%) Frame = +3 Query: 192 YRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKT--------------------KHPQ 311 Y+LGR LG GSFG + + + T +VAIK+ N + HP Sbjct: 42 YKLGRTLGIGSFGRVKIAEHALTGHKVAIKILNRRKIKNMEMEEKVRREIKILRLFMHPH 101 Query: 312 LLYESKLYRVLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRK--LSLKTVL 485 ++ +LY V++ T I LVM+ + +LF + K L Sbjct: 102 II---RLYEVIETPTDI-------------YLVMEYVNSG--ELFDYIVEKGRLQEDEAR 143 Query: 486 MLADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIP 665 Q+I+ VE+ H +HRD+KP+N L L + N V + DFGL+ RD Sbjct: 144 NFFQQIISGVEYCHRNMVVHRDLKPENLL--LDSKCN-VKIADFGLSNIMRDG------- 193 Query: 666 YRENKNLTGTARYASVSTHLG-IEQSRRDDMESLGYVLMYFLRGSLPW 806 K G+ YA+ G + D+ S G +L L G+LP+ Sbjct: 194 -HFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYALLCGTLPF 240
>Q9UPZ9:ICK_HUMAN Serine/threonine-protein kinase ICK - Homo sapiens (Human)| Length = 632 Score = 62.0 bits (149), Expect = 8e-09 Identities = 45/155 (29%), Positives = 75/155 (48%), Gaps = 4/155 (2%) Frame = +3 Query: 186 NKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKT---KHPQLLYESKLYRVLQGGT 356 N+Y R+LG G++G + LG ++++ E +AIK K + L E K + L Sbjct: 2 NRYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLKKLNHAN 61 Query: 357 GISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKS 536 + +K E D+ + + + +L L N+ + + Q++ + FIH Sbjct: 62 -VVKLKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHG 120 Query: 537 FLHRDIKPDNFL-MGLGKRANQVYMIDFGLAKKYR 638 F HRD+KP+N L MG V + DFGLA++ R Sbjct: 121 FFHRDLKPENLLCMG----PELVKIADFGLAREIR 151
>Q4U925:CSK2A_THEAN Casein kinase II subunit alpha - Theileria annulata| Length = 348 Score = 62.0 bits (149), Expect = 8e-09 Identities = 44/154 (28%), Positives = 80/154 (51%), Gaps = 2/154 (1%) Frame = +3 Query: 180 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK-LENVKTKHPQLLYESKLYRVLQGGT 356 V + Y + RK+G G F E++ G N T ++ IK L+ VK K ++ E K+ + L+GG Sbjct: 51 VPDSYEIVRKIGRGKFSEVFEGLNTVTKDKCVIKILKPVKKK--KIKREIKILQNLRGGP 108 Query: 357 GISNVKWFGVEGDYNVLVMDVLGPSLEDL-FSFCNRKLSLKTVLMLADQMINRVEFIHSK 533 I +K + D ++ + + F L+++ + Q++ + + HS+ Sbjct: 109 NI--IKLLDIVKDPQSRTPSLIFEHVNNTDFKTLYPTLTIQDIKYYIYQLLKAMNYCHSQ 166 Query: 534 SFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKY 635 +HRDIKP N ++ K+ + +ID+GLA+ Y Sbjct: 167 GIMHRDIKPHNVMIDHEKKI--LRLIDWGLAEFY 198
>O64817:CSK23_ARATH Probable casein kinase II subunit alpha - Arabidopsis thaliana| (Mouse-ear cress) Length = 333 Score = 62.0 bits (149), Expect = 8e-09 Identities = 44/150 (29%), Positives = 79/150 (52%), Gaps = 2/150 (1%) Frame = +3 Query: 192 YRLGRKLGSGSFGEIYLGTNVQTNEEVAIK-LENVKTKHPQLLYESKLYRVLQGGTGISN 368 Y + RK+G G + E++ G NV TNE IK L+ VK K ++ E K+ + L GG I Sbjct: 34 YEVVRKVGRGKYSEVFEGKNVNTNERCVIKILKPVKKK--KIKREIKILQNLCGGPNI-- 89 Query: 369 VKWFGVEGDYNVLVMDVLGPSLEDL-FSFCNRKLSLKTVLMLADQMINRVEFIHSKSFLH 545 VK + + D + ++ + + F L+ + +++ ++F HS+ +H Sbjct: 90 VKLYDIVRDEHSKTPSLVFEFVNSVDFKVLYPTLTDYDIRYYIYELLKALDFCHSQGIMH 149 Query: 546 RDIKPDNFLMGLGKRANQVYMIDFGLAKKY 635 RD+KP N + + + ++ +ID+GLA+ Y Sbjct: 150 RDVKPHNVM--IDHQLRKLRLIDWGLAEFY 177
>Q61RA2:CHK1_CAEBR Serine/threonine-protein kinase chk-1 - Caenorhabditis briggsae| Length = 493 Score = 62.0 bits (149), Expect = 8e-09 Identities = 60/226 (26%), Positives = 99/226 (43%), Gaps = 12/226 (5%) Frame = +3 Query: 165 PMEPRVGNK-YRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLE--------NVKTKHPQLL 317 P P N+ YR+ R LG G+FGE+ L N N ++A+ ++ N + L Sbjct: 16 PTAPGESNECYRVIRTLGEGAFGEVLLIVN-NKNPDMAVAMKKMQITTQANTNNIRKEFL 74 Query: 318 YESKLYRVLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVL--ML 491 + KL +V G E ++ L ++ +LF + T + Sbjct: 75 IQQKLSKV--GHDNFIRAIGMRTENGFHFLFLEYADGG--ELFDKIEPDHGMPTAIAQFY 130 Query: 492 ADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYR 671 Q+I +++IH +HRDIKP+N L+ ++ + + DFG+A YR+ + + Sbjct: 131 FRQLIEGLKYIHDCDIVHRDIKPENLLL---TTSHVLKISDFGMATLYRNEGKERLLDLS 187 Query: 672 ENKNLTGTARYASVSTHLGIE-QSRRDDMESLGYVLMYFLRGSLPW 806 GT YA+ G + + D+ S G VL+ L G LPW Sbjct: 188 -----CGTIPYAAPEVCAGGKYRGPPIDVWSSGIVLIAMLTGELPW 228
>Q5ZKN1:CDK9_CHICK Cell division protein kinase 9 - Gallus gallus (Chicken)| Length = 372 Score = 62.0 bits (149), Expect = 8e-09 Identities = 47/161 (29%), Positives = 80/161 (49%), Gaps = 11/161 (6%) Frame = +3 Query: 186 NKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK---LENVKTKHP-QLLYESKLYRVLQGG 353 +KY K+G G+FGE++ + QT ++VA+K +EN K P L E K+ ++L+ Sbjct: 17 SKYEKLAKIGQGTFGEVFKAKHRQTGKKVALKKVLMENEKEGFPITALREIKILQLLKHE 76 Query: 354 TGISNVKWFGVEGD-YN------VLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINR 512 ++ ++ + YN LV D L L S + K +L + + ++N Sbjct: 77 NVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNTHVKFTLSEIKKVMQMLLNG 136 Query: 513 VEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKY 635 + +IH LHRD+K N L+ R + + DFGLA+ + Sbjct: 137 LYYIHRNKILHRDMKAANVLI---TRDGVLKLADFGLARAF 174
>Q52WX2:SBK1_HUMAN Serine/threonine-protein kinase SBK1 - Homo sapiens (Human)| Length = 424 Score = 61.6 bits (148), Expect = 1e-08 Identities = 56/215 (26%), Positives = 94/215 (43%), Gaps = 5/215 (2%) Frame = +3 Query: 180 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENV-KTKHPQLLYESKLYRVLQGGT 356 V Y L R+LG G++G++ L T ++A+K N KTK L E + L Sbjct: 49 VTKHYELVRELGKGTYGKVDLVVYKGTGTKMALKFVNKSKTKLKNFLREVSITNSLSSSP 108 Query: 357 GISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLK--TVLMLADQMINRVEFIHS 530 I V E + + P+ DLF ++ L TV Q+ ++F+H Sbjct: 109 FIIKVFDVVFETEDCYVFAQEYAPA-GDLFDIIPPQVGLPEDTVKRCVQQLGLALDFMHG 167 Query: 531 KSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKY--RDTSTHQHIPYRENKNLTGTARY 704 + +HRDIKP+N L+ + +V + DFG+ ++ R IPY + R Sbjct: 168 RQLVHRDIKPENVLL-FDRECRRVKLADFGMTRRVGCRVKRVSGTIPYTA-PEVCQAGRA 225 Query: 705 ASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQ 809 ++ G+ D+ + G ++ L G+ PW+ Sbjct: 226 DGLAVDTGV------DVWAFGVLIFCVLTGNFPWE 254
>Q9Y6R4:M3K4_HUMAN Mitogen-activated protein kinase kinase kinase 4 - Homo sapiens| (Human) Length = 1607 Score = 61.6 bits (148), Expect = 1e-08 Identities = 52/214 (24%), Positives = 97/214 (45%), Gaps = 4/214 (1%) Frame = +3 Query: 177 RVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK-LENVKTKHPQLLYESKLYRVLQGG 353 +V K++ G K+G G +G++Y +V T E +A+K + H + + ++ +G Sbjct: 1337 KVTFKWQRGNKIGEGQYGKVYTCISVDTGELMAMKEIRFQPNDHKTIKETADELKIFEGI 1396 Query: 354 TGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSK 533 + V++FGVE + + + L L + + + Q+ + +H Sbjct: 1397 KHPNLVRYFGVELHREEMYIFMEYCDEGTLEEVSRLGLQEHVIRLYSKQITIAINVLHEH 1456 Query: 534 SFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYAS- 710 +HRDIK N + + + + DFG + K ++ + Q +P N L GTA Y + Sbjct: 1457 GIVHRDIKGANIFL---TSSGLIKLGDFGCSVKLKNNA--QTMPGEVNSTL-GTAAYMAP 1510 Query: 711 --VSTHLGIEQSRRDDMESLGYVLMYFLRGSLPW 806 ++ G R D+ SLG V++ + G PW Sbjct: 1511 EVITRAKGEGHGRAADIWSLGCVVIEMVTGKRPW 1544
>O61267:LOK_DROME Ovarian-specific serine/threonine-protein kinase Lok - Drosophila| melanogaster (Fruit fly) Length = 476 Score = 61.6 bits (148), Expect = 1e-08 Identities = 77/297 (25%), Positives = 127/297 (42%), Gaps = 27/297 (9%) Frame = +3 Query: 180 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKL--ENVKTKHPQLLYESKLYRVLQGG 353 + Y + RKLGSG++G + L + +T ++ A+K+ +N+ + S RVL Sbjct: 170 INKTYYVNRKLGSGAYGLVRLVYDTRTCQQFAMKIVKKNMLSGARPSTNFSDPDRVLNEA 229 Query: 354 TGISNVKWFGV----------EGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQM 503 + N+ V + Y VL G L + S N+ LS + QM Sbjct: 230 KIMKNLSHPCVVRMHDIVDKPDSVYMVLEFMRGGDLLNRIIS--NKLLSEDISKLYFYQM 287 Query: 504 INRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKN 683 + V+++H + HRD+KPDN L+ + + DFGL+K + S + Sbjct: 288 CHAVKYLHDRGITHRDLKPDNVLLETNDEETLLKVSDFGLSKFVQKDSV--------MRT 339 Query: 684 LTGTARYASVSTHL--GIE-QSRRDDMESLGYVLMYFLRGSLPWQ---GLKAGTKKQK-- 839 L GT Y + + G E +++ D+ SLG VL L G+LP+ G A + +K Sbjct: 340 LCGTPLYVAPEVLITGGREAYTKKVDIWSLGVVLFTCLSGTLPFSDEYGTPAAQQIKKGR 399 Query: 840 -------YEKISERKIATSIEALCRGYPSEFQSFFHYCRSLRFEDSPDYQYLKRLFR 989 ++ +S+R I + P S +S D+P Q KRL + Sbjct: 400 FAYGHPSWKSVSQR-AKLLINQMLIVDPERRPSIDDVLQSSWLRDAPMLQKAKRLMK 455
>Q18846:KS6A2_CAEEL Putative ribosomal protein S6 kinase alpha-2 - Caenorhabditis elegans| Length = 772 Score = 61.6 bits (148), Expect = 1e-08 Identities = 62/239 (25%), Positives = 115/239 (48%), Gaps = 15/239 (6%) Frame = +3 Query: 189 KYRLGRK----LGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGT 356 KY+L + LG G+F + V + A+K+ + K Q E+++ ++QG Sbjct: 377 KYKLDKSDAGLLGKGAFSVVRRCERVVDGAQFAVKIVSQKFAS-QAQREARILEMVQGHP 435 Query: 357 GISNVKWFGVEGDYNVLVMDVL-GPSLEDLFSFCNRKLSLKTVLMLAD---QMINRVEFI 524 I + + + LVM++L G L + RKL T AD Q+++ V+++ Sbjct: 436 NIVQLHDVHSDPLHFYLVMEILTGNELLERI----RKLERFTESEAADIMRQLVSAVKYL 491 Query: 525 HSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTG--TA 698 H K +HRD+KP+N L + ++ ++DFG A+ ++ Q + + +T T Sbjct: 492 HDKRIVHRDLKPENILFESIDSSARLRLVDFGFARLLPNSMEQQLKSVQVLRKMTPCFTL 551 Query: 699 RYASVSTHLGI-----EQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKISER 860 +YA+ L + E + + D+ SLG VL L G +P+ A ++++ +I +R Sbjct: 552 QYAAPEV-LDVGDSQPEYNEQCDLWSLGVVLFTMLSGQVPFH---ARSRQESATEIMQR 606
>Q6GLD8:CDK9_XENTR Cell division protein kinase 9 - Xenopus tropicalis (Western clawed| frog) (Silurana tropicalis) Length = 376 Score = 61.6 bits (148), Expect = 1e-08 Identities = 48/165 (29%), Positives = 79/165 (47%), Gaps = 15/165 (9%) Frame = +3 Query: 186 NKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK---LENVKTKHP-QLLYESKLYRVLQGG 353 +KY K+G G+FGE++ + QT ++VA+K +EN K P L E K+ ++L+ Sbjct: 17 SKYERLAKIGQGTFGEVFKAKHRQTGKKVALKKVLMENEKEGFPITALREIKILQLLKHE 76 Query: 354 TGISNV-----KWFGVEGDYN------VLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQ 500 ++ + K YN LV D L L S + K +L + + Sbjct: 77 NVVNLIEICRTKISPTANQYNRCKGTIFLVFDFCEHDLAGLLSNAHVKFTLSEIKKVMQM 136 Query: 501 MINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKY 635 ++N + +IH LHRD+K N L+ R + + DFGLA+ + Sbjct: 137 LLNGLYYIHRNKILHRDMKAANVLI---TRDGVLKLADFGLARAF 178
>Q4V862:CDK9A_XENLA Cell division protein kinase 9-A - Xenopus laevis (African clawed| frog) Length = 376 Score = 61.6 bits (148), Expect = 1e-08 Identities = 48/165 (29%), Positives = 79/165 (47%), Gaps = 15/165 (9%) Frame = +3 Query: 186 NKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK---LENVKTKHP-QLLYESKLYRVLQGG 353 +KY K+G G+FGE++ + QT ++VA+K +EN K P L E K+ ++L+ Sbjct: 17 SKYERLAKIGQGTFGEVFKAKHRQTGKKVALKKVLMENEKEGFPITALREIKILQLLKHE 76 Query: 354 TGISNV-----KWFGVEGDYN------VLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQ 500 ++ + K YN LV D L L S + K +L + + Sbjct: 77 NVVNLIEICRTKVSPTANQYNRCKGTIFLVFDFCEHDLAGLLSNAHVKFTLSEIKKVMQM 136 Query: 501 MINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKY 635 ++N + +IH LHRD+K N L+ R + + DFGLA+ + Sbjct: 137 LLNGLYYIHRNKILHRDMKAANVLI---TRDGVLKLADFGLARAF 178
>O88445:AURKC_MOUSE Serine/threonine-protein kinase 13 - Mus musculus (Mouse)| Length = 282 Score = 61.6 bits (148), Expect = 1e-08 Identities = 66/259 (25%), Positives = 109/259 (42%), Gaps = 18/259 (6%) Frame = +3 Query: 186 NKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK------LENVKTKHPQLLYESKLYRVLQ 347 N + +GR LG G FG +YL + + VA+K +E +H QL E ++ LQ Sbjct: 14 NDFEIGRPLGRGKFGRVYLARLKENHFIVALKVLFKSEIEKEGLEH-QLRREVEIQAHLQ 72 Query: 348 GGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNR--KLSLKTVLMLADQMINRVEF 521 + +F D + ++ P E L+ R KL + + ++ + + + Sbjct: 73 HRNILRLYNYF--YDDTRIYLILEYAPGGE-LYKELQRHQKLDQQRTATIIQELSDALTY 129 Query: 522 IHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTAR 701 H K +HRDIKP+N L+GL +V + DFG + H P K + GT Sbjct: 130 CHEKKVIHRDIKPENLLLGLN---GEVKISDFGWS---------VHTPSLRRKTMCGTLD 177 Query: 702 YASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKIS--ERKIATS 875 Y + D+ +G + L G P++ + T + Y +I + K +S Sbjct: 178 YLPPEMIAQKPYNEMVDLWCIGVLCYELLVGKPPFE---SSTSSETYRRIRQVDFKFPSS 234 Query: 876 IEA--------LCRGYPSE 908 + A L R +PSE Sbjct: 235 VPAGAQDLISKLLRYHPSE 253
>Q9UQB9:AURKC_HUMAN Serine/threonine-protein kinase 13 - Homo sapiens (Human)| Length = 309 Score = 61.6 bits (148), Expect = 1e-08 Identities = 57/240 (23%), Positives = 99/240 (41%), Gaps = 7/240 (2%) Frame = +3 Query: 162 PPMEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK------LENVKTKHPQLLYE 323 P M + + +GR LG G FG +YL +++ VA+K +E +H QL E Sbjct: 33 PAMRRLTVDDFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEH-QLRRE 91 Query: 324 SKLYRVLQGGTGISNVKWF-GVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQ 500 ++ LQ + +F Y +L G ++L + KL + + ++ Sbjct: 92 IEIQAHLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQK--SEKLDEQRTATIIEE 149 Query: 501 MINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENK 680 + + + + H K +HRDIKP+N L+G +V + DFG + H P K Sbjct: 150 LADALTYCHDKKVIHRDIKPENLLLGF---RGEVKIADFGWS---------VHTPSLRRK 197 Query: 681 NLTGTARYASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKISER 860 + GT Y G + D+ +G + L G P++ ++ K+ R Sbjct: 198 TMCGTLDYLPPEMIEGRTYDEKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVR 257
>Q7T6Y1:YR436_MIMIV Putative serine/threonine-protein kinase R436 - Mimivirus| Length = 276 Score = 61.2 bits (147), Expect = 1e-08 Identities = 62/252 (24%), Positives = 115/252 (45%), Gaps = 13/252 (5%) Frame = +3 Query: 186 NKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTGIS 365 + Y L + + + I++GT+ T ++V IK+ + K K + + + I Sbjct: 4 SNYSLDKLIQNRKSKRIFIGTDTITLQKVVIKIYDDKNKSKESILRDIHIPSILNHPNII 63 Query: 366 NVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLS---------LKTVLMLADQMINRVE 518 +K + + D N M V+ P +++ S N + L ++ + Q+++ + Sbjct: 64 KIKDYVEDLDSNK--MYVIYPYIDNTISLRNLPVDKFDVTDLFKLYYIIDILIQVVDAIS 121 Query: 519 FIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTA 698 ++H + +HRDIKPDN L+ ++V++IDF L+ D + P R K GT Sbjct: 122 YMHDNNIVHRDIKPDNILLN-----DKVHLIDFDLS----DQLDNPKFPVR--KGTIGTP 170 Query: 699 RYASVSTHLGIEQ--SRRDDMESLGYVLMYFL-RGSLPWQGLKAGTKKQKYEKISERKIA 869 + + I Q ++ D+ SLG + Y L + LP+ K +KY ++ E +IA Sbjct: 171 NFMAPEIWWKINQVDYKKTDIYSLGITMYYLLNKRKLPY-------KAKKYSEL-EYQIA 222 Query: 870 TSIEALCR-GYP 902 + GYP Sbjct: 223 NHKPKISNSGYP 234
>P10936:YES_XENLA Tyrosine-protein kinase Yes - Xenopus laevis (African clawed frog)| Length = 537 Score = 61.2 bits (147), Expect = 1e-08 Identities = 66/271 (24%), Positives = 117/271 (43%), Gaps = 3/271 (1%) Frame = +3 Query: 195 RLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQ-LLYESKLYRVLQGGTGISNV 371 RL KLG G FGE+++GT T + VAIK T P+ L E+++ + L+ + Sbjct: 272 RLDVKLGQGCFGEVWIGTWNGTTK-VAIKTLKPGTMMPEAFLQEAQIMKKLRHDKLVPLY 330 Query: 372 KWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFLHRD 551 E Y V + G L+ L + L L ++ +A Q+ + + +I +++HRD Sbjct: 331 AVVSEEPIYIVTEYMIKGSLLDFLKEGNGKYLKLPQLVDMAAQIADGMAYIERMNYIHRD 390 Query: 552 IKPDNFLMGLGKRANQVYMI-DFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVSTHLG 728 ++ N L+G N V I DFGLA+ D Y + ++ + L Sbjct: 391 LRAANILVG----DNLVCKIADFGLARLIEDNE------YTARQGAKFPIKWTAPEAALY 440 Query: 729 IEQSRRDDMESLGYVLMYFL-RGSLPWQGLKAGTKKQKYEKISERKIATSIEALCRGYPS 905 + + D+ S G +L + +G +P+ G+ ++ E++ ER C P Sbjct: 441 GRFTIKSDVWSFGILLTELVAKGRVPYPGM---VNREVLEQV-ERGYRMPCPQRC---PE 493 Query: 906 EFQSFFHYCRSLRFEDSPDYQYLKRLFRDLF 998 C ++ P ++Y++ D F Sbjct: 494 SLHELMKLCWKKDPDERPTFEYIQSFLEDYF 524
>Q9BXA6:TSSK6_HUMAN Testis-specific serine/threonine-protein kinase 6 - Homo sapiens| (Human) Length = 273 Score = 61.2 bits (147), Expect = 1e-08 Identities = 57/213 (26%), Positives = 97/213 (45%), Gaps = 8/213 (3%) Frame = +3 Query: 192 YRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLL--YESKLYRVLQGGTGIS 365 Y+LGR +G GS+ ++ + T+ + VAIK+ + + P + + + +L+G Sbjct: 12 YKLGRTIGEGSYSKVKVATSKKYKGTVAIKVVDRRRAPPDFVNKFLPRELSILRGVRHPH 71 Query: 366 NVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLM--LADQMINRVEFIHSKSF 539 V F N + V+ + DL R + V L Q+ V ++H Sbjct: 72 IVHVFEFIEVCNGKLYIVMEAAATDLLQAVQRNGRIPGVQARDLFAQIAGAVRYLHDHHL 131 Query: 540 LHRDIKPDNFLMGLGKRANQVYMIDFGLAKK---YRDTSTHQHIPYRENKNLTGTARYAS 710 +HRD+K +N L+ +R +V + DFG ++ Y D ST G+A YAS Sbjct: 132 VHRDLKCENVLLSPDER--RVKLTDFGFGRQAHGYPDLST----------TYCGSAAYAS 179 Query: 711 VSTHLGIE-QSRRDDMESLGYVLMYFLRGSLPW 806 LGI ++ D+ S+G VL + G +P+ Sbjct: 180 PEVLLGIPYDPKKYDVWSMGVVLYVMVTGCMPF 212
>Q5R4L1:PLK2_PONPY Serine/threonine-protein kinase PLK2 - Pongo pygmaeus (Orangutan)| Length = 685 Score = 61.2 bits (147), Expect = 1e-08 Identities = 86/397 (21%), Positives = 155/397 (39%), Gaps = 10/397 (2%) Frame = +3 Query: 3 PPPHNEKEYPQSHTSIPAQTLATNLRNSSLAQVPP*LDALNLGGGSVACVRARPPMEPRV 182 P P E + PQS +P + +S G ++ R ++P Sbjct: 36 PQPPEESQPPQSQAQVPPAAAHHHHHHSH-------------SGPEIS----RIIVDPTT 78 Query: 183 GNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKL---ENVKTKHPQ--LLYESKLYRVLQ 347 G +Y G+ LG G F + Y T++ N+ A K+ V H + + E +L+R+L Sbjct: 79 GKRYCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQREKIDKEIELHRILH 138 Query: 348 GGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIH 527 + +F + + +L+ S+ + + L+ V Q+++ ++++H Sbjct: 139 HKHVVQFYHYFEDKENIYILLEYCSRRSMAHILK-ARKVLTEPEVRYYLRQIVSGLKYLH 197 Query: 528 SKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYA 707 + LHRD+K NF + A ++ + DFGLA + + + GT Y Sbjct: 198 EQEILHRDLKLGNFFI---NEAMELKVGDFGLAARLEPLE-------HRRRTICGTPNYL 247 Query: 708 SVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKISERKIATSIEAL 887 S D+ +LG V+ L G P++ K+ Y I E + L Sbjct: 248 SPEVLNKQGHGCESDIWALGCVMYTMLLGRPPFE---TTNLKETYRCIREARYTMPSSLL 304 Query: 888 CRGYPSEFQSFFHYCRSLRFEDSPDYQYLKRLFRDLFIREGFQFDYVFD---WTILKYQQ 1058 P++ H S+ ++ D L + R F +GF D + T+ + Sbjct: 305 A---PAK-----HLIASMLSKNPEDRPSLDDIIRHDFFLQGFTPDRLSSSCCHTVPDFHL 356 Query: 1059 SQMTSVPPRAIAAA--AGQSSGMAPIASNNRLSATEE 1163 S + AAA G+ I ++NR+S +E Sbjct: 357 SSPAKNFFKKAAAALFGGKKDKARYIDTHNRVSKEDE 393
>Q11053:PKNH_MYCTU Probable serine/threonine-protein kinase pknH - Mycobacterium| tuberculosis Length = 626 Score = 61.2 bits (147), Expect = 1e-08 Identities = 59/227 (25%), Positives = 101/227 (44%), Gaps = 8/227 (3%) Frame = +3 Query: 171 EPRVGNK---YRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVK-TKHP----QLLYES 326 + RVG+ Y L R LG G GE+Y + VA+KL + +K P ++ E+ Sbjct: 6 DSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRERMKREA 65 Query: 327 KLYRVLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMI 506 ++ LQ + + V+G + + V G L+ + + V ++ Q+ Sbjct: 66 RIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAIIT-QIA 124 Query: 507 NRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNL 686 + ++ H+ +HRD+KP N L+ R + Y++DFG+A D Q Sbjct: 125 SALDAAHADGVMHRDVKPQNILI---TRDDFAYLVDFGIASATTDEKLTQ------LGTA 175 Query: 687 TGTARYASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGT 827 GT +Y + E + R D+ +L VL L G+ P++ AGT Sbjct: 176 VGTWKYMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGT 222
>Q7U095:PKNH_MYCBO Probable serine/threonine-protein kinase pknH - Mycobacterium bovis| Length = 596 Score = 61.2 bits (147), Expect = 1e-08 Identities = 59/227 (25%), Positives = 101/227 (44%), Gaps = 8/227 (3%) Frame = +3 Query: 171 EPRVGNK---YRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVK-TKHP----QLLYES 326 + RVG+ Y L R LG G GE+Y + VA+KL + +K P ++ E+ Sbjct: 6 DSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRERMKREA 65 Query: 327 KLYRVLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMI 506 ++ LQ + + V+G + + V G L+ + + V ++ Q+ Sbjct: 66 RIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAIIT-QIA 124 Query: 507 NRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNL 686 + ++ H+ +HRD+KP N L+ R + Y++DFG+A D Q Sbjct: 125 SALDAAHADGVMHRDVKPQNILI---TRDDFAYLVDFGIASATTDEKLTQ------LGTA 175 Query: 687 TGTARYASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGT 827 GT +Y + E + R D+ +L VL L G+ P++ AGT Sbjct: 176 VGTWKYMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGT 222
>Q9Z986:PKND_CHLPN Serine/threonine-protein kinase pknD - Chlamydia pneumoniae| (Chlamydophila pneumoniae) Length = 932 Score = 61.2 bits (147), Expect = 1e-08 Identities = 66/241 (27%), Positives = 105/241 (43%), Gaps = 31/241 (12%) Frame = +3 Query: 189 KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK------LENVKTKHPQLLYESKLYRVLQG 350 +Y + R +G G GE+YL + + +VA+K EN K + L E+++ L Sbjct: 3 RYDIVRIIGKGGMGEVYLAYDPVCSRKVALKKIREDLAENPLLKR-RFLREARIAADLIH 61 Query: 351 GTGISNVKWFGVEGDYNVLVMDVL-GPSLEDLFSFCNRKLSLK----------TVLMLAD 497 G+ V E D M + G +L+ L +K SL L + Sbjct: 62 -PGVVPVYTIYSEKDPVYYTMPYIEGYTLKTLLKSVWQKESLSKELAEKTSVGAFLSIFH 120 Query: 498 QMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLA--------------KKY 635 ++ +E++HS+ LHRD+KPDN L+GL ++ ++D+G A K Sbjct: 121 KICCTIEYVHSRGILHRDLKPDNILLGL---FSEAVILDWGAAVACGEEEDLLDIDVSKE 177 Query: 636 RDTSTHQHIPYRENKNLTGTARYASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGL 815 S+ IP R + GT Y + LG S+ D+ +LG VL L S P++ Sbjct: 178 EVLSSRMTIPGR----IVGTPDYMAPERLLGHPASKSTDIYALGVVLYQMLTLSFPYRRK 233 Query: 816 K 818 K Sbjct: 234 K 234
>Q05512:MARK2_MOUSE Serine/threonine-protein kinase MARK2 - Mus musculus (Mouse)| Length = 776 Score = 61.2 bits (147), Expect = 1e-08 Identities = 52/218 (23%), Positives = 102/218 (46%), Gaps = 4/218 (1%) Frame = +3 Query: 171 EPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK-LENVKTKHPQLLYESKLYRVLQ 347 +P +GN YRL + +G G+F ++ L ++ T +EVA+K ++ + L + R+++ Sbjct: 47 QPHIGN-YRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMK 105 Query: 348 GGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSF--CNRKLSLKTVLMLADQMINRVEF 521 + VK F V L + + S ++F + + ++ K Q+++ V++ Sbjct: 106 VLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQY 165 Query: 522 IHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTAR 701 H K +HRD+K +N L+ + + DFG + ++ + + G+ Sbjct: 166 CHQKFIVHRDLKAENLLLDADM---NIKIADFGFSNEFTFGN--------KLDTFCGSPP 214 Query: 702 YASVSTHLGIE-QSRRDDMESLGYVLMYFLRGSLPWQG 812 YA+ G + D+ SLG +L + GSLP+ G Sbjct: 215 YAAPELFQGKKIDGPEVDVWSLGVILYTLVSGSLPFDG 252
>O08648:M3K4_MOUSE Mitogen-activated protein kinase kinase kinase 4 - Mus musculus| (Mouse) Length = 1597 Score = 61.2 bits (147), Expect = 1e-08 Identities = 52/214 (24%), Positives = 96/214 (44%), Gaps = 4/214 (1%) Frame = +3 Query: 177 RVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK-LENVKTKHPQLLYESKLYRVLQGG 353 +V K++ G K+G G +G++Y +V T E +A+K + H + + ++ +G Sbjct: 1327 KVTFKWQRGNKIGEGQYGKVYTCISVDTGELMAMKEIRFQPNDHKTIKETADELKIFEGI 1386 Query: 354 TGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSK 533 + V++FGVE + + + L L + + Q+ + +H Sbjct: 1387 KHPNLVRYFGVELHREEMYIFMEYCDEGTLEEVSRLGLQEHVIRLYTKQITVAINVLHEH 1446 Query: 534 SFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYAS- 710 +HRDIK N + + + + DFG + K ++ + Q +P N L GTA Y + Sbjct: 1447 GIVHRDIKGANIFL---TSSGLIKLGDFGCSVKLKNNA--QTMPGEVNSTL-GTAAYMAP 1500 Query: 711 --VSTHLGIEQSRRDDMESLGYVLMYFLRGSLPW 806 ++ G R D+ SLG V++ + G PW Sbjct: 1501 EVITRAKGEGHGRAADIWSLGCVVIEMVTGKRPW 1534
>Q62726:ICK_RAT Serine/threonine-protein kinase ICK - Rattus norvegicus (Rat)| Length = 629 Score = 61.2 bits (147), Expect = 1e-08 Identities = 45/155 (29%), Positives = 75/155 (48%), Gaps = 4/155 (2%) Frame = +3 Query: 186 NKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKT---KHPQLLYESKLYRVLQGGT 356 N+Y ++LG G++G + LG ++++ E +AIK K + L E K + L Sbjct: 2 NRYTTIKQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLKKLNHAN 61 Query: 357 GISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKS 536 I +K E D+ + + + +L L N+ + + Q++ + FIH Sbjct: 62 -IVKLKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHG 120 Query: 537 FLHRDIKPDNFL-MGLGKRANQVYMIDFGLAKKYR 638 F HRD+KP+N L MG V + DFGLA++ R Sbjct: 121 FFHRDLKPENLLCMG----PELVKIADFGLAREIR 151
>Q9JKV2:ICK_MOUSE Serine/threonine-protein kinase ICK - Mus musculus (Mouse)| Length = 629 Score = 61.2 bits (147), Expect = 1e-08 Identities = 45/155 (29%), Positives = 75/155 (48%), Gaps = 4/155 (2%) Frame = +3 Query: 186 NKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKT---KHPQLLYESKLYRVLQGGT 356 N+Y ++LG G++G + LG ++++ E +AIK K + L E K + L Sbjct: 2 NRYTTIKQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLKKLNHAN 61 Query: 357 GISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKS 536 I +K E D+ + + + +L L N+ + + Q++ + FIH Sbjct: 62 -IVKLKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHG 120 Query: 537 FLHRDIKPDNFL-MGLGKRANQVYMIDFGLAKKYR 638 F HRD+KP+N L MG V + DFGLA++ R Sbjct: 121 FFHRDLKPENLLCMG----PELVKIADFGLAREIR 151
>O22040:ANP1_ARATH Mitogen-activated protein kinase kinase kinase ANP1 - Arabidopsis| thaliana (Mouse-ear cress) Length = 666 Score = 61.2 bits (147), Expect = 1e-08 Identities = 51/215 (23%), Positives = 94/215 (43%), Gaps = 10/215 (4%) Frame = +3 Query: 192 YRLGRKLGSGSFGEIYLGTNVQTNEEVAIK----------LENVKTKHPQLLYESKLYRV 341 +R G+ +G G+FG +Y+G N+ + E +A+K E + +L E KL + Sbjct: 69 WRKGQLIGRGAFGTVYMGMNLDSGELLAVKQVLIAANFASKEKTQAHIQELEEEVKLLKN 128 Query: 342 LQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEF 521 L + + + N+L+ V G S+ L V Q++ +E+ Sbjct: 129 LSHPNIVRYLGTVREDDTLNILLEFVPGGSISSLLEKFG-PFPESVVRTYTRQLLLGLEY 187 Query: 522 IHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTAR 701 +H+ + +HRDIK N L+ + + DFG +K+ + +T K++ GT Sbjct: 188 LHNHAIMHRDIKGANILV---DNKGCIKLADFGASKQVAELAT-----MTGAKSMKGTPY 239 Query: 702 YASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPW 806 + + L S D+ S+G ++ + G PW Sbjct: 240 WMAPEVILQTGHSFSADIWSVGCTVIEMVTGKAPW 274
>Q02977:YRK_CHICK Proto-oncogene tyrosine-protein kinase Yrk - Gallus gallus (Chicken)| Length = 536 Score = 60.8 bits (146), Expect = 2e-08 Identities = 67/276 (24%), Positives = 118/276 (42%), Gaps = 8/276 (2%) Frame = +3 Query: 195 RLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQ-LLYESKLYRVLQGGTGISNV 371 +L +KLG+G FGE+++GT T + VA+K T P+ L E+++ + L+ + Sbjct: 271 QLLQKLGNGQFGEVWMGTWNGTTK-VAVKTLKPGTMSPEAFLEEAQIMKRLRHDKLVQLY 329 Query: 372 KWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFLHRD 551 E Y V G L+ L R L L ++ +A Q+ + +I +++HRD Sbjct: 330 AVVSEEPIYIVTEFMSQGSLLDFLKDGDGRYLKLPQLVDMAAQIAAGMAYIERMNYIHRD 389 Query: 552 IKPDNFLMGLGKRANQVYMI-DFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVSTHLG 728 ++ N L+G N V I DFGLA+ D Y + ++ + L Sbjct: 390 LRAANILVG----DNLVCKIADFGLARLIEDNE------YTARQGAKFPIKWTAPEAALF 439 Query: 729 IEQSRRDDMESLGYVLMYFL-RGSLPWQGLKAGTKKQKYEKISERKIATSIEALCR---- 893 + + + D+ S G +L + +G +P+ G+ + R++ +E R Sbjct: 440 GKFTIKSDVWSFGILLTELVTKGRVPYPGM------------NNREVLEQVERGYRMQCP 487 Query: 894 -GYPSEFQSFFHYCRSLRFEDSPDYQYLKRLFRDLF 998 G P C E+ P ++YL+ D F Sbjct: 488 GGCPPSLHDVMVQCWKREPEERPTFEYLQSFLEDYF 523
>Q90ZY6:TLK1_DANRE Serine/threonine-protein kinase tousled-like 1 - Danio rerio| (Zebrafish) (Brachydanio rerio) Length = 756 Score = 60.8 bits (146), Expect = 2e-08 Identities = 63/289 (21%), Positives = 119/289 (41%), Gaps = 22/289 (7%) Frame = +3 Query: 174 PRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKL---------ENVKTKHPQLLYES 326 P + +Y L LG G F E+Y ++ A+K+ E + H E Sbjct: 444 PTLNERYLLLHLLGRGGFSEVYKAFDLFEQRYAAVKIHQLNKNWREEKKENYHKHACREY 503 Query: 327 KLYRVLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMI 506 ++++ L + +F ++ D V++ + D + ++ +S K + Q++ Sbjct: 504 RIHKQLDHPRIVKLYDYFSLDTDTFCTVLEFCEGNDLDFYLKQHKLMSEKEARSIVMQIV 563 Query: 507 NRVEFIHS--KSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENK 680 N + +++ S +H D+KP N L+ G ++ + DFGL+K D S + Sbjct: 564 NALRYLNEIKPSIIHYDLKPGNILLVDGTACGEIKITDFGLSKIMDDDSYGV-----DGM 618 Query: 681 NLT----GTARYASVSTHLGIEQ----SRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQ 836 +LT GT Y + ++ S + D+ S+G + L G P+ G + Sbjct: 619 DLTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFFQCLYGRKPF-----GHNQS 673 Query: 837 KYEKISERKIATSIEALCRGYP---SEFQSFFHYCRSLRFEDSPDYQYL 974 + + + E I + E P +E ++F C + R ED D L Sbjct: 674 QQDILQENTILKATEVQFPAKPVASNEAKAFIRRCLAYRKEDRSDVHQL 722
>Q5R4F3:TAOK3_PONPY Serine/threonine-protein kinase TAO3 - Pongo pygmaeus (Orangutan)| Length = 898 Score = 60.8 bits (146), Expect = 2e-08 Identities = 47/159 (29%), Positives = 70/159 (44%), Gaps = 5/159 (3%) Frame = +3 Query: 207 KLGSGSFGEIYLGTNVQTNEEVAIKL-----ENVKTKHPQLLYESKLYRVLQGGTGISNV 371 ++G GSFG +Y TN TNE VAIK + K +L E K R L+ I Sbjct: 29 EIGHGSFGAVYFATNAHTNEVVAIKKMSYSGKQTHEKWQDILKEVKFLRQLKHPNTI-EY 87 Query: 372 KWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFLHRD 551 K ++ LVM+ S DL + L + + ++ + ++HS + +HRD Sbjct: 88 KGCYLKEHTAWLVMEYCLGSASDLLEVHKKPLQEVEIAAITHGALHGLAYLHSHALIHRD 147 Query: 552 IKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPY 668 IK N L+ QV + DFG A ++ PY Sbjct: 148 IKAGNILL---TEPGQVKLADFGSASVASPANSFVGTPY 183
>Q10407:MKH1_SCHPO MAP kinase kinase kinase mkh1 - Schizosaccharomyces pombe (Fission| yeast) Length = 1116 Score = 60.8 bits (146), Expect = 2e-08 Identities = 65/261 (24%), Positives = 115/261 (44%), Gaps = 28/261 (10%) Frame = +3 Query: 189 KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKL----ENVKTKHPQLLYE-----SKLYRV 341 K+ G +G+G++G+++L N+ T E +A+K + + +H QL + + + Sbjct: 824 KWMKGELIGNGTYGKVFLAMNINTGELIAVKQVEIPQTINGRHDQLRKDIVDSINAEISM 883 Query: 342 LQGGTGISNVKWFG---VEGDYNVLVMDVLGPSLEDLFSFCNRK---LSLKTVLMLADQM 503 + ++ V++ G E D ++ + V G S+ C R + V ++ Q+ Sbjct: 884 IADLDHLNIVQYLGFEKTETDISIFLEYVSGGSI----GRCLRNYGPFEEQLVRFVSRQV 939 Query: 504 INRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKN 683 + + ++HSK +HRD+K DN L+ + DFG++K H Y + N Sbjct: 940 LYGLSYLHSKGIIHRDLKADNLLIDFD---GVCKISDFGISK-------HSDNVYDNDAN 989 Query: 684 LT------GTARYASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQG-------LKAG 824 L+ A + H G S + D+ SLG V++ L G PW K G Sbjct: 990 LSMQGSIFWMAPEVIHNDHQG--YSAKVDVWSLGCVVLEMLAGRRPWSTDEAIQAMFKLG 1047 Query: 825 TKKQKYEKISERKIATSIEAL 887 T+K+ SE S EA+ Sbjct: 1048 TEKKAPPIPSELVSQVSPEAI 1068
>O43077:MDE3_SCHPO Sporulation protein kinase mde3 - Schizosaccharomyces pombe| (Fission yeast) Length = 559 Score = 60.8 bits (146), Expect = 2e-08 Identities = 57/163 (34%), Positives = 85/163 (52%), Gaps = 15/163 (9%) Frame = +3 Query: 186 NKYRLGRKLGSGSFGEIYLGTNVQTN---EEVAIK-LENV---KTKHPQL-LYESKLYRV 341 ++Y + +KLG GSFG +YL + N E VA+K L+N K KH L L ES R Sbjct: 19 DRYLVKQKLGDGSFGTVYLAQRKEKNGLYETVAVKKLKNSSKPKPKHELLKLRESLALRK 78 Query: 342 LQGGTGISNVKWFGVEGDYNV-LVMDVLGPSLEDLFSFCNRKLSLK-TVLMLADQMINRV 515 + + ++ ++ N+ LVM+ + +L LF +L K T + Q+I+ + Sbjct: 79 ISKHPCLIDLLETFMDPYRNIFLVMEFMDCNLFQLFKRRQGRLFTKETAFNILLQIISGI 138 Query: 516 EFIHSKSFLHRDIKPDNFLMG--LGKRANQVYMI---DFGLAK 629 E IH F+HRDIKP+N L+ K + Y I DFGLA+ Sbjct: 139 EHIHKHGFMHRDIKPENILVKRISPKPISSRYSIKLGDFGLAR 181
>O76484:CSK2A_SPOFR Casein kinase II subunit alpha - Spodoptera frugiperda (Fall| armyworm) Length = 353 Score = 60.8 bits (146), Expect = 2e-08 Identities = 44/157 (28%), Positives = 79/157 (50%), Gaps = 9/157 (5%) Frame = +3 Query: 192 YRLGRKLGSGSFGEIYLGTNVQTNEEVAIK-LENVKTKHPQLLYESKLYRVLQGGTGISN 368 Y+L RKLG G + E++ N+ NE+ +K L+ VK K ++ E K+ L+GGT I Sbjct: 39 YQLVRKLGRGKYSEVFEAINITNNEKCVVKILKPVKKK--KIKREIKILENLRGGTNIIT 96 Query: 369 VKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLAD--------QMINRVEFI 524 ++ +V D + + +F N + L+D +++ +++ Sbjct: 97 LQ---------AVVKDPVSRTPALIFEHVNNTDFKQLYQTLSDYDIRYYLYELLKALDYC 147 Query: 525 HSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKY 635 HS +HRD+KP N ++ R ++ +ID+GLA+ Y Sbjct: 148 HSMGIMHRDVKPHNVMIDHDHR--KLRLIDWGLAEFY 182
>Q5SUV5:SGK85_MOUSE Uncharacterized serine/threonine-protein kinase SgK085 - Mus| musculus (Mouse) Length = 386 Score = 60.5 bits (145), Expect = 2e-08 Identities = 59/217 (27%), Positives = 96/217 (44%), Gaps = 6/217 (2%) Frame = +3 Query: 180 VGNKYRLGRK--LGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQ----LLYESKLYRV 341 V N Y + + LG G FG+++ T ++A K+ +KT+ + + E + Sbjct: 101 VDNLYTVSKSEILGGGRFGQVHKCEEKATGLKLAAKI--IKTRGAKDKEDVKNEISVMNQ 158 Query: 342 LQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEF 521 L I F + D +LVMDV G L D N L+ ++ Q+ + + Sbjct: 159 LDHVNLIQLYDAFESKHDI-ILVMDVEGGELFDRIIDENCNLTELDTILFMKQICEGIRY 217 Query: 522 IHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTAR 701 +H LH D+KP+N L + + A Q+ +IDFGLA++Y+ P + K GT Sbjct: 218 MHQMYILHLDLKPENILC-VNRDAKQIKIIDFGLARRYK--------PREKLKVNFGTPE 268 Query: 702 YASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQG 812 + + S DM S+G + L G P+ G Sbjct: 269 FLAPEVVNYDFVSFSTDMWSVGVITYMLLSGLSPFLG 305
>Q9R011:PLK3_RAT Serine/threonine-protein kinase PLK3 - Rattus norvegicus (Rat)| Length = 615 Score = 60.5 bits (145), Expect = 2e-08 Identities = 56/218 (25%), Positives = 94/218 (43%), Gaps = 5/218 (2%) Frame = +3 Query: 171 EPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKL---ENVKTKH--PQLLYESKLY 335 +PR G Y GR LG G F Y T+ +T+ A+K+ V H +++ E +L+ Sbjct: 24 DPRSGRTYIKGRLLGKGGFARCYEATDTETSIAYAVKVIPQSRVAKPHQREKIINEIELH 83 Query: 336 RVLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRV 515 R LQ + F + + + SL ++ L V Q+++ + Sbjct: 84 RDLQHRHIVRFSHHFEDADNIYIFLELCSRKSLAHIWK-ARHTLLEPEVRYYLRQILSGL 142 Query: 516 EFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGT 695 +++H + LHRD+K NF + ++ + DFGLA + P + K + GT Sbjct: 143 KYLHQRGILHRDLKLGNFFI---TDNMELKVGDFGLAARLEP-------PEQRKKTICGT 192 Query: 696 ARYASVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQ 809 Y + L D+ SLG V+ L GS P++ Sbjct: 193 PNYVAPEVLLRQGHGPEADVWSLGCVMYTLLCGSPPFE 230
>Q9NYY3:PLK2_HUMAN Serine/threonine-protein kinase PLK2 - Homo sapiens (Human)| Length = 685 Score = 60.5 bits (145), Expect = 2e-08 Identities = 86/397 (21%), Positives = 155/397 (39%), Gaps = 10/397 (2%) Frame = +3 Query: 3 PPPHNEKEYPQSHTSIPAQTLATNLRNSSLAQVPP*LDALNLGGGSVACVRARPPMEPRV 182 P P E + PQS +P + +S G ++ R ++P Sbjct: 36 PQPPEESQPPQSQAQVPPAAPHHHHHHSH-------------SGPEIS----RIIVDPTT 78 Query: 183 GNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKL---ENVKTKHPQ--LLYESKLYRVLQ 347 G +Y G+ LG G F + Y T++ N+ A K+ V H + + E +L+R+L Sbjct: 79 GKRYCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQREKIDKEIELHRILH 138 Query: 348 GGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIH 527 + +F + + +L+ S+ + + L+ V Q+++ ++++H Sbjct: 139 HKHVVQFYHYFEDKENIYILLEYCSRRSMAHILK-ARKVLTEPEVRYYLRQIVSGLKYLH 197 Query: 528 SKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYA 707 + LHRD+K NF + A ++ + DFGLA + + + GT Y Sbjct: 198 EQEILHRDLKLGNFFI---NEAMELKVGDFGLAARLEPLE-------HRRRTICGTPNYL 247 Query: 708 SVSTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKISERKIATSIEAL 887 S D+ +LG V+ L G P++ K+ Y I E + L Sbjct: 248 SPEVLNKQGHGCESDIWALGCVMYTMLLGRPPFE---TTNLKETYRCIREARYTMPSSLL 304 Query: 888 CRGYPSEFQSFFHYCRSLRFEDSPDYQYLKRLFRDLFIREGFQFDYVFD---WTILKYQQ 1058 P++ H S+ ++ D L + R F +GF D + T+ + Sbjct: 305 A---PAK-----HLIASMLSKNPEDRPSLDDIIRHDFFLQGFTPDRLSSSCCHTVPDFHL 356 Query: 1059 SQMTSVPPRAIAAA--AGQSSGMAPIASNNRLSATEE 1163 S + AAA G+ I ++NR+S +E Sbjct: 357 SSPAKNFFKKAAAALFGGKKDKARYIDTHNRVSKEDE 393
>Q62829:PAK3_RAT Serine/threonine-protein kinase PAK 3 - Rattus norvegicus (Rat)| Length = 544 Score = 60.5 bits (145), Expect = 2e-08 Identities = 50/208 (24%), Positives = 94/208 (45%), Gaps = 2/208 (0%) Frame = +3 Query: 189 KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQG-GTGIS 365 KY K+G G+ G +Y ++ T +EVAIK N++ + + L +++ + + I Sbjct: 267 KYTRFEKIGQGASGTVYTALDIATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIV 326 Query: 366 NVKWFGVEGDYNVLVMDVL-GPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFL 542 N + GD +VM+ L G SL D+ + + + + + + ++F+HS + Sbjct: 327 NYLDSYLVGDELWVVMEYLAGGSLTDVVT--ETCMDEGQIAAVCRECLQALDFLHSNQVI 384 Query: 543 HRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVSTH 722 HRDIK DN L+G+ V + DFG + + + + GT + + Sbjct: 385 HRDIKSDNILLGMD---GSVKLTDFGFCAQITPEQS-------KRSTMVGTPYWMAPEVV 434 Query: 723 LGIEQSRRDDMESLGYVLMYFLRGSLPW 806 + D+ SLG + + + G P+ Sbjct: 435 TRKAYGPKVDIWSLGIMAIEMVEGEPPY 462
>Q7YQL3:PAK3_PONPY Serine/threonine-protein kinase PAK 3 - Pongo pygmaeus (Orangutan)| Length = 559 Score = 60.5 bits (145), Expect = 2e-08 Identities = 50/208 (24%), Positives = 94/208 (45%), Gaps = 2/208 (0%) Frame = +3 Query: 189 KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQG-GTGIS 365 KY K+G G+ G +Y ++ T +EVAIK N++ + + L +++ + + I Sbjct: 282 KYTRFEKIGQGASGTVYTALDIATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIV 341 Query: 366 NVKWFGVEGDYNVLVMDVL-GPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFL 542 N + GD +VM+ L G SL D+ + + + + + + ++F+HS + Sbjct: 342 NYLDSYLVGDELWVVMEYLAGGSLTDVVT--ETCMDEGQIAAVCRECLQALDFLHSNQVI 399 Query: 543 HRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVSTH 722 HRDIK DN L+G+ V + DFG + + + + GT + + Sbjct: 400 HRDIKSDNILLGMD---GSVKLTDFGFCAQITPEQS-------KRSTMVGTPYWMAPEVV 449 Query: 723 LGIEQSRRDDMESLGYVLMYFLRGSLPW 806 + D+ SLG + + + G P+ Sbjct: 450 TRKAYGPKVDIWSLGIMAIEMVEGEPPY 477
>Q7YQL4:PAK3_PANTR Serine/threonine-protein kinase PAK 3 - Pan troglodytes| (Chimpanzee) Length = 559 Score = 60.5 bits (145), Expect = 2e-08 Identities = 50/208 (24%), Positives = 94/208 (45%), Gaps = 2/208 (0%) Frame = +3 Query: 189 KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQG-GTGIS 365 KY K+G G+ G +Y ++ T +EVAIK N++ + + L +++ + + I Sbjct: 282 KYTRFEKIGQGASGTVYTALDIATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIV 341 Query: 366 NVKWFGVEGDYNVLVMDVL-GPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFL 542 N + GD +VM+ L G SL D+ + + + + + + ++F+HS + Sbjct: 342 NYLDSYLVGDELWVVMEYLAGGSLTDVVT--ETCMDEGQIAAVCRECLQALDFLHSNQVI 399 Query: 543 HRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVSTH 722 HRDIK DN L+G+ V + DFG + + + + GT + + Sbjct: 400 HRDIKSDNILLGMD---GSVKLTDFGFCAQITPEQS-------KRSTMVGTPYWMAPEVV 449 Query: 723 LGIEQSRRDDMESLGYVLMYFLRGSLPW 806 + D+ SLG + + + G P+ Sbjct: 450 TRKAYGPKVDIWSLGIMAIEMVEGEPPY 477
>Q61036:PAK3_MOUSE Serine/threonine-protein kinase PAK 3 - Mus musculus (Mouse)| Length = 559 Score = 60.5 bits (145), Expect = 2e-08 Identities = 50/208 (24%), Positives = 94/208 (45%), Gaps = 2/208 (0%) Frame = +3 Query: 189 KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQG-GTGIS 365 KY K+G G+ G +Y ++ T +EVAIK N++ + + L +++ + + I Sbjct: 282 KYTRFEKIGQGASGTVYTALDIATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIV 341 Query: 366 NVKWFGVEGDYNVLVMDVL-GPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFL 542 N + GD +VM+ L G SL D+ + + + + + + ++F+HS + Sbjct: 342 NYLDSYLVGDELWVVMEYLAGGSLTDVVT--ETCMDEGQIAAVCRECLQALDFLHSNQVI 399 Query: 543 HRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVSTH 722 HRDIK DN L+G+ V + DFG + + + + GT + + Sbjct: 400 HRDIKSDNILLGMD---GSVKLTDFGFCAQITPEQS-------KRSTMVGTPYWMAPEVV 449 Query: 723 LGIEQSRRDDMESLGYVLMYFLRGSLPW 806 + D+ SLG + + + G P+ Sbjct: 450 TRKAYGPKVDIWSLGIMAIEMVEGEPPY 477
>O75914:PAK3_HUMAN Serine/threonine-protein kinase PAK 3 - Homo sapiens (Human)| Length = 559 Score = 60.5 bits (145), Expect = 2e-08 Identities = 50/208 (24%), Positives = 94/208 (45%), Gaps = 2/208 (0%) Frame = +3 Query: 189 KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQG-GTGIS 365 KY K+G G+ G +Y ++ T +EVAIK N++ + + L +++ + + I Sbjct: 282 KYTRFEKIGQGASGTVYTALDIATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIV 341 Query: 366 NVKWFGVEGDYNVLVMDVL-GPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFL 542 N + GD +VM+ L G SL D+ + + + + + + ++F+HS + Sbjct: 342 NYLDSYLVGDELWVVMEYLAGGSLTDVVT--ETCMDEGQIAAVCRECLQALDFLHSNQVI 399 Query: 543 HRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVSTH 722 HRDIK DN L+G+ V + DFG + + + + GT + + Sbjct: 400 HRDIKSDNILLGMD---GSVKLTDFGFCAQITPEQS-------KRSTMVGTPYWMAPEVV 449 Query: 723 LGIEQSRRDDMESLGYVLMYFLRGSLPW 806 + D+ SLG + + + G P+ Sbjct: 450 TRKAYGPKVDIWSLGIMAIEMVEGEPPY 477
>Q6P431:MKNK2_XENLA MAP kinase-interacting serine/threonine-protein kinase 2 - Xenopus| laevis (African clawed frog) Length = 467 Score = 60.5 bits (145), Expect = 2e-08 Identities = 55/230 (23%), Positives = 99/230 (43%), Gaps = 10/230 (4%) Frame = +3 Query: 153 RARPPMEPRVGNKYRLGRK-LGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQ--LLYE 323 RA R + Y+L ++ LG G++ ++ N+ TN+E A+K+ + H + + E Sbjct: 69 RATDSFTGRFDDMYQLQQEILGEGAYAKVQSCINLITNKEYAVKIIEKRPGHSRSRVFRE 128 Query: 324 SKLYRVLQGGTGISNVKWFGVEGDYNVLVMDVL--GPSLEDLFSFCNRKLSLKTVLMLAD 497 ++ QG + + + F E D LV + + G L + R + + + Sbjct: 129 VEMLYQCQGHSNVLELIEFFEEEDKFYLVFEKMCGGSILNHIHR--RRHFNEREASFVVR 186 Query: 498 QMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYREN 677 + + ++H+K HRD+KP+N L + + V + DF L + S I E Sbjct: 187 DIAEALNYLHNKGIAHRDLKPENILCESPHQVSPVKICDFDLGSGIKLNSDCSPISTPEL 246 Query: 678 KNLTGTARYASVSTHLGIEQ-----SRRDDMESLGYVLMYFLRGSLPWQG 812 G+A Y + + +R D+ SLG +L L G P+ G Sbjct: 247 LTPCGSAEYMAPEVVEAFNEEASIYDKRCDLWSLGVILYIMLSGYPPFVG 296
>Q95M30:HCK_MACFA Tyrosine-protein kinase HCK - Macaca fascicularis (Crab eating| macaque) (Cynomolgus monkey) Length = 504 Score = 60.5 bits (145), Expect = 2e-08 Identities = 76/313 (24%), Positives = 131/313 (41%), Gaps = 19/313 (6%) Frame = +3 Query: 138 SVACVRARP--PME------PRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENV 293 SV CV ++P P E PR +L +KLG+G FGE+++ T + +VA+K Sbjct: 216 SVPCVSSKPQKPWEKDAWEIPR--ESLKLEKKLGAGQFGEVWMAT-YNKHTKVAVKTMKP 272 Query: 294 KTKHPQ-LLYESKLYRVLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLS 470 + + L E+ L + LQ + E Y + G L+ L S K Sbjct: 273 GSMSVEAFLAEANLMKTLQHDKLVKLHAVVTKEPIYIITEFMAKGSLLDFLKSDEGSKQP 332 Query: 471 LKTVLMLADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMI-DFGLAKKYRDTS 647 L ++ + Q+ + FI ++++HRD++ N L+ A+ V I DFGLA+ D Sbjct: 333 LPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVS----ASLVCKIADFGLARIIEDNE 388 Query: 648 THQHIPYRENKNLTGTARYASVSTHLGIEQSRRDDMESLGYVLMYFLR-GSLPWQGLKAG 824 Y + ++ + + + D+ S G +LM + G +P+ G+ Sbjct: 389 ------YTAREGAKFPIKWTAPEAINFGSSTIKSDVWSFGILLMEIVTYGRIPYPGM--- 439 Query: 825 TKKQKYEKISERKIATSIEALCRGY--------PSEFQSFFHYCRSLRFEDSPDYQYLKR 980 S ++ I AL RGY P E + C R E+ P ++Y++ Sbjct: 440 ---------SNPEV---IRALERGYRMPRPENCPEELYNIMMRCWKNRPEERPTFEYIQS 487 Query: 981 LFRDLFIREGFQF 1019 + D + Q+ Sbjct: 488 VLDDFYTATESQY 500
>P19139:CSK21_RAT Casein kinase II subunit alpha - Rattus norvegicus (Rat)| Length = 391 Score = 60.5 bits (145), Expect = 2e-08 Identities = 93/379 (24%), Positives = 156/379 (41%), Gaps = 31/379 (8%) Frame = +3 Query: 192 YRLGRKLGSGSFGEIYLGTNVQTNEEVAIK-LENVKTKHPQLLYESKLYRVLQGGTGISN 368 Y+L RKLG G + E++ N+ NE+V +K L+ VK K ++ E K+ L+GG I Sbjct: 39 YQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKK--KIKREIKILENLRGGPNIIT 96 Query: 369 VKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLAD--------QMINRVEFI 524 + +V D + + +F N + L D +++ +++ Sbjct: 97 LA---------DIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYC 147 Query: 525 HSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGLAKKYRDTSTHQHIPYRENKNLTGTARY 704 HS +HRD+KP N ++ R ++ +ID+GLA+ Y + N+ +RY Sbjct: 148 HSMGIMHRDVKPHNVMIDHEHR--KLRLIDWGLAEFYHPGQEY---------NVRVASRY 196 Query: 705 ASVSTHLGIEQSRRD---DMESLGYVLMYFLRGSLPW-----------QGLKAGTKKQKY 842 L ++ D DM SLG +L + P+ + K + Y Sbjct: 197 FK-GPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLY 255 Query: 843 EKISERKIATS---IEALCRGYPSEFQSFFHYCRSLRFEDSPDYQYLKRLFR-----DLF 998 + I + I + L R ++ F H + +L +L R L Sbjct: 256 DYIDKYNIELDPRFNDILGRHSRKRWERFVH-SENQHLVSPEALDFLDKLLRYDHQSRLT 314 Query: 999 IREGFQFDYVFDWTILKYQQSQMTSVPPRAIAAAAGQSSGMAPIASNNRLSATEEGRISG 1178 RE + Y + T++K Q++M+S AG + G P++S N + SG Sbjct: 315 AREAMEHPYFY--TVVK-DQARMSS---------AGMAGGSTPVSSANMM--------SG 354 Query: 1179 WSADPTRSQVPPTGINAGS 1235 S+ PT S P G AGS Sbjct: 355 ISSVPTPS---PLGPLAGS 370 Database: uniprot_sprot.fasta.out Posted date: Jul 19, 2007 5:58 PM Number of letters in database: 100,686,439 Number of sequences in database: 274,295 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 274295 Number of Hits to DB: 354,644,050 Number of extensions: 8119031 Number of successful extensions: 27454 Number of sequences better than 10.0: 2209 Number of HSP's gapped: 25980 Number of HSP's successfully gapped: 2259 Length of query: 636 Length of database: 100,686,439 Length adjustment: 120 Effective length of query: 516 Effective length of database: 67,771,039 Effective search space: 34969856124 Effective search space used: 34969856124 Neighboring words threshold: 12 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
