ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | FLbaf126d01 |
|---|---|
| Clone Library Name | barley_pub |
>Q2MHE4:HT1_ARATH Serine/threonine-protein kinase HT1 - Arabidopsis thaliana (Mouse-ear| cress) Length = 390 Score = 216 bits (549), Expect = 4e-55 Identities = 118/335 (35%), Positives = 187/335 (55%), Gaps = 1/335 (0%) Frame = +1 Query: 727 RTGSLGSSDYVRADKID-LTSLDIQLEQQLNKKWSKSNIKSLGPKADWEIDLAKLEIRHV 903 +T ++ + + D + S + LE + + W S G + +W DL++L I + Sbjct: 36 KTNRYAEAETMEKKRFDSMESWSMILESENVETWEASK----GEREEWTADLSQLFIGNK 91 Query: 904 IAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFATEAETTALRTSFKQEVAVWHKLSHPNVT 1083 A G + +YRG Y + VAVK++ T A+ L FK EVA+ +L HPN+ Sbjct: 92 FASGAHSRIYRGIYKQRAVAVKMVRIPTHKEETRAK---LEQQFKSEVALLSRLFHPNIV 148 Query: 1084 KFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYLIKNRRRKLAYKVVV 1263 +F+ A K PV C++ EY++ G L+ YL K L+ + V+ Sbjct: 149 QFIAACK-----KPPVY-------------CIITEYMSQGNLRMYLNKKEPYSLSIETVL 190 Query: 1264 QLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGVARVEAQNPKDMTGATGT 1443 +LALD+SRG+ YLHS+ ++HRD+K+ N+LL+ + +K+ADFG + +E Q ++ G GT Sbjct: 191 RLALDISRGMEYLHSQGVIHRDLKSNNLLLNDEMRVKVADFGTSCLETQC-REAKGNMGT 249 Query: 1444 LGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDMPYPDLSFADVSSAVVHQNLRPDIPR 1623 +MAPE++ KPY RK DVYSFGI LWE+ +P+ ++ + AV +N RP +P Sbjct: 250 YRWMAPEMIKEKPYTRKVDVYSFGIVLWELTTALLPFQGMTPVQAAFAVAEKNERPPLPA 309 Query: 1624 CCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALD 1728 C A A+++++CW NP KRPD +V ++E D Sbjct: 310 SCQPALAHLIKRCWSENPSKRPDFSNIVAVLEKYD 344
>Q7T6X2:YR826_MIMIV Putative serine/threonine-protein kinase/receptor R826 precursor -| Mimivirus Length = 1657 Score = 173 bits (438), Expect = 3e-42 Identities = 96/283 (33%), Positives = 155/283 (54%), Gaps = 2/283 (0%) Frame = +1 Query: 865 WEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFATEAETTALRTSFKQE 1044 W I+ ++++ I G+YG VYRG + VA+K F + ++E Sbjct: 1392 WVINYDEIKMGEQIGLGSYGVVYRGKWKNVDVAIKK-------FIKQKIDENHLLGIREE 1444 Query: 1045 VAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYLI 1224 +A KL HPN+ VGAS+ ++ C+V EY+A G L+ + Sbjct: 1445 IAFLKKLHHPNIITMVGASLKKPNI------------------CIVTEYMAKGNLRDAM- 1485 Query: 1225 KNRRRKLAYKVVVQLALDLSRGLSYLHS--RKIVHRDVKTENMLLDTQRNLKIADFGVAR 1398 + KL + +++ +++++G+SYLHS I+HRD+K N+L+D N+KIADFG AR Sbjct: 1486 RTCTPKLEWHQKIKILVNIAKGISYLHSFDPPIIHRDIKPSNILIDENWNVKIADFGFAR 1545 Query: 1399 VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDMPYPDLSFADV 1578 ++ +N + GT + APE++ Y+ K DV+SFGI +WEV C P+ +F + Sbjct: 1546 IKEENA--IMTRCGTPCWTAPEIIRNDIYDEKVDVFSFGIVMWEVLTCKEPFIGANFMKI 1603 Query: 1579 SSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVV 1707 + ++ +++RP IP+ CP FA +MRKCW KRP MD+V+ Sbjct: 1604 TMDIL-EDVRPKIPQDCPEEFAKLMRKCWHAKSTKRPTMDDVI 1645 Score = 152 bits (384), Expect = 6e-36 Identities = 99/307 (32%), Positives = 156/307 (50%), Gaps = 10/307 (3%) Frame = +1 Query: 850 GPKADWEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFATEAETTALRT 1029 G DWEID +LE+ + G +G V++GT+ G +VAVK++ + T + Sbjct: 774 GISDDWEIDFHELELGEQLGTGAFGEVHKGTWRGTEVAVKMIS------PDKTITKDIER 827 Query: 1030 SFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTL 1209 +FK EV V L HPNV F+ AS + C+V+E++A G+L Sbjct: 828 NFKDEVRVMTTLRHPNVVLFMAASTKPPKM------------------CIVMEFMALGSL 869 Query: 1210 KQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFG 1389 L + + + V++A S+G+ +LHS I HRD+K+ N+LLD + N+K++DFG Sbjct: 870 HDLLKNELIPDIPFALKVKIAYQASKGMHFLHSSGITHRDLKSLNLLLDIKWNVKVSDFG 929 Query: 1390 VAR----VEAQNPKDMTGATGTLGYMAPEVL--DGKPYNRKCDVYSFGICLWEVYCCDMP 1551 + + V++ NP+ GT+ + APE+L D + DVYSFGI +WE+ D P Sbjct: 930 LTKFKSDVKSINPEKF---AGTIQWTAPEILSEDREVDYILSDVYSFGIIMWELITRDQP 986 Query: 1552 YPDLSFADVSSAVVHQNLRPDIPRCCPSAFA----NIMRKCWDGNPDKRPDMDEVVQLME 1719 Y +S A ++ +V+ N RP I S A ++ CW +P RP E++ + Sbjct: 987 YFGMSPAAIAVSVIRDNYRPVISDQLRSEVAPEYIELLTSCWHFDPTIRPTFLEIMTRLS 1046 Query: 1720 ALDTSKG 1740 L G Sbjct: 1047 NLMGDSG 1053
>Q05609:CTR1_ARATH Serine/threonine-protein kinase CTR1 - Arabidopsis thaliana| (Mouse-ear cress) Length = 821 Score = 167 bits (424), Expect = 1e-40 Identities = 106/291 (36%), Positives = 157/291 (53%), Gaps = 3/291 (1%) Frame = +1 Query: 862 DWEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFATEAETTALRTSFKQ 1041 D +I L I+ I G++GTV+R + G VAVK+L E F E LR Sbjct: 543 DMDIPWCDLNIKEKIGAGSFGTVHRAEWHGSDVAVKILM--EQDFHAERVNEFLR----- 595 Query: 1042 EVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYL 1221 EVA+ +L HPN+ F+GA +L I V EYL+ G+L + L Sbjct: 596 EVAIMKRLRHPNIVLFMGAVTQPPNLSI------------------VTEYLSRGSLYRLL 637 Query: 1222 IKN-RRRKLAYKVVVQLALDLSRGLSYLHSRK--IVHRDVKTENMLLDTQRNLKIADFGV 1392 K+ R +L + + +A D+++G++YLH+R IVHRD+K+ N+L+D + +K+ DFG+ Sbjct: 638 HKSGAREQLDERRRLSMAYDVAKGMNYLHNRNPPIVHRDLKSPNLLVDKKYTVKVCDFGL 697 Query: 1393 ARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDMPYPDLSFA 1572 +R++A A GT +MAPEVL +P N K DVYSFG+ LWE+ P+ +L+ A Sbjct: 698 SRLKASTFLSSKSAAGTPEWMAPEVLRDEPSNEKSDVYSFGVILWELATLQQPWGNLNPA 757 Query: 1573 DVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 V +AV + R +IPR A I+ CW P KRP ++ L+ L Sbjct: 758 QVVAAVGFKCKRLEIPRNLNPQVAAIIEGCWTNEPWKRPSFATIMDLLRPL 808
>P18160:KYK1_DICDI Non-receptor tyrosine kinase spore lysis A - Dictyostelium discoideum| (Slime mold) Length = 1584 Score = 162 bits (410), Expect = 5e-39 Identities = 94/308 (30%), Positives = 165/308 (53%), Gaps = 17/308 (5%) Frame = +1 Query: 856 KADWEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFATEAETTALRTSF 1035 ++++EID +LE I +G +G V RG + VA+K++ + + +T + F Sbjct: 1279 RSEYEIDFNELEFGQTIGKGFFGEVKRGYWRETDVAIKII------YRDQFKTKSSLVMF 1332 Query: 1036 KQEVAVWHKLSHPNVTKFVGA-SMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLK 1212 + EV + KL HPNV +F+GA + G D C+V E++ GG+L+ Sbjct: 1333 QNEVGILSKLRHPNVVQFLGACTAGGEDHH-----------------CIVTEWMGGGSLR 1375 Query: 1213 QYLIKN-RRRKLAYKVVVQLALDLSRGLSYLH--SRKIVHRDVKTENMLLDTQRN----- 1368 Q+L + + + ++LALD+++G++YLH + I+HRD+ + N+LLD + Sbjct: 1376 QFLTDHFNLLEQNPHIRLKLALDIAKGMNYLHGWTPPILHRDLSSRNILLDHNIDPKNPV 1435 Query: 1369 --------LKIADFGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICL 1524 KI+DFG++R++ + MT + G + YMAPEV G + K DVYS+G+ L Sbjct: 1436 VSSRQDIKCKISDFGLSRLKKEQASQMTQSVGCIPYMAPEVFKGDSNSEKSDVYSYGMVL 1495 Query: 1525 WEVYCCDMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEV 1704 +E+ D P D+ ++ +++ RP IP S + I+ +CWD NPD RP ++ Sbjct: 1496 FELLTSDEPQQDMKPMKMAHLAAYESYRPPIPLTTSSKWKEILTQCWDSNPDSRPTFKQI 1555 Query: 1705 VQLMEALD 1728 + ++ ++ Sbjct: 1556 IVHLKEME 1563
>Q5UQG7:YR818_MIMIV Putative serine/threonine-protein kinase/receptor R818 precursor -| Mimivirus Length = 1651 Score = 162 bits (409), Expect = 7e-39 Identities = 92/283 (32%), Positives = 147/283 (51%), Gaps = 2/283 (0%) Frame = +1 Query: 865 WEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFATEAETTALRTSFKQE 1044 W I+ ++I I G+YG V G + VAVK F + F+ E Sbjct: 1387 WIINYDDIQIGKQIGVGSYGIVNMGKWKNINVAVKK-------FVKQKIDEKQMLEFRAE 1439 Query: 1045 VAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYLI 1224 +A +L HP++ +GA + R N+ C+V E++ G+L+ + Sbjct: 1440 IAFLSQLRHPHIILMIGACL-------------KRPNI-----CIVTEFMGNGSLRNVI- 1480 Query: 1225 KNRRRKLAYKVVVQLALDLSRGLSYLHSRK--IVHRDVKTENMLLDTQRNLKIADFGVAR 1398 + K +K+ +++ + G+ YLH+ I+HRD+K N+L+D N+KIADFG AR Sbjct: 1481 --KTTKPEWKLKIKMLYQTALGIGYLHNSDPIIIHRDIKPSNILVDDSMNVKIADFGFAR 1538 Query: 1399 VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDMPYPDLSFADV 1578 ++ +N + GT + APE++ G+ Y K DV+SFGI +WEV C P+ +F V Sbjct: 1539 IKEEN--SVMTRCGTPCWTAPEIIRGEKYTEKVDVFSFGIVMWEVLTCKEPFSGCNFMKV 1596 Query: 1579 SSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVV 1707 S ++ + RP IP CP F +M++CW PDKRP M++V+ Sbjct: 1597 SMDIL-EGARPQIPSDCPIDFTKLMKQCWHAKPDKRPSMEDVI 1638 Score = 137 bits (345), Expect = 2e-31 Identities = 96/312 (30%), Positives = 157/312 (50%), Gaps = 9/312 (2%) Frame = +1 Query: 862 DWEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFATEAETTALRTSFKQ 1041 +WE+D +L+ + G G V++ + G +VAVK L +AE +FKQ Sbjct: 785 EWEVDFHELDFMESLGSGGSGEVFKAMWKGTEVAVKKLV--NSNITKDAER-----NFKQ 837 Query: 1042 EVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYL 1221 E+ L HPNV F+ AS ++ C+V+E+++ G+L L Sbjct: 838 EIHRMTSLRHPNVVLFMAASTRPPNM------------------CIVMEFMSLGSLYDLL 879 Query: 1222 IKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGVARV 1401 ++ + +++A ++G+ +LHS IVHRD+K+ N+LLD++ N+K++DFG+ ++ Sbjct: 880 GNELVTEIPPVLRIRIAYQAAKGMHFLHSSDIVHRDLKSLNLLLDSKWNVKVSDFGLTKI 939 Query: 1402 EAQNP-KDMT--GATGTLGYMAPEVLDGKP--YNRKCDVYSFGICLWEVYCCDMPYPDLS 1566 + N K T + ++ + APEVL K DVYSFGI +WE+ PY LS Sbjct: 940 KDNNKGKSSTKEDSVCSIQWTAPEVLSEKQDIDYILADVYSFGIIMWELMTRLRPYIGLS 999 Query: 1567 FADVSSAVVHQNLRPDIP----RCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDTS 1734 A ++ AV+ NLRP+I S + ++ CW + RP +++M L T Sbjct: 1000 PAAIAVAVIRDNLRPEIQEEDINLMSSDYVELVNICWHKDTMIRPSF---LEIMTKLSTL 1056 Query: 1735 KGGGMIPDGQSS 1770 GG I G S+ Sbjct: 1057 IGGSGITTGTST 1068
>Q7T6Y2:YR831_MIMIV Putative serine/threonine-protein kinase/receptor R831 precursor -| Mimivirus Length = 1624 Score = 161 bits (407), Expect = 1e-38 Identities = 101/284 (35%), Positives = 147/284 (51%), Gaps = 2/284 (0%) Frame = +1 Query: 865 WEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFATEAETTALRTSFKQE 1044 W I+ ++ I I G+YG V+ G + G VAVK F + + F+ E Sbjct: 1357 WIINYDEISIGKQIGLGSYGIVFNGKWKGVDVAVKK-------FVKQKLSETQLLEFRAE 1409 Query: 1045 VAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYLI 1224 +A +L H N+ F+GA + ++ C+V EY+ G L+ L Sbjct: 1410 MAFLSELKHSNIVTFIGACIKKPNI------------------CIVTEYMRMGNLRDVL- 1450 Query: 1225 KNRRRKLAYKVVVQLALDLSRGLSYLHSRK--IVHRDVKTENMLLDTQRNLKIADFGVAR 1398 KN K+ + ++L + G+ YLHS IVHRD+K N+L+D N+KIADFG AR Sbjct: 1451 KNPDIKITFANKLKLLYGAAMGIDYLHSSNPMIVHRDIKPANILVDEHFNVKIADFGFAR 1510 Query: 1399 VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDMPYPDLSFADV 1578 ++ N MT GT + APEV+ G+ Y K DV+SFG+ +WEV P+ + +F V Sbjct: 1511 IKEDNTT-MTRC-GTPCWTAPEVIRGEKYCEKADVFSFGVVMWEVLTGKEPFAECNFMKV 1568 Query: 1579 SSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQ 1710 S ++ + RP IP CP FA +++KCW KRP M EVVQ Sbjct: 1569 SLDIL-EGGRPIIPSDCPHEFAKLIKKCWHAKAHKRPTMTEVVQ 1611 Score = 157 bits (396), Expect = 2e-37 Identities = 91/290 (31%), Positives = 161/290 (55%), Gaps = 8/290 (2%) Frame = +1 Query: 862 DWEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFATEAETTALRTSFKQ 1041 DWEID ++LEI + G YG VY+ + G +VAVKL+ +++ + + SF + Sbjct: 778 DWEIDFSELEIGETLGTGGYGEVYKSIWKGTEVAVKLI-------SSKHVSKDMERSFFE 830 Query: 1042 EVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYL 1221 EV + L HPNV F+ AS + ++ C+V+E+++ G+L L Sbjct: 831 EVKIMTSLRHPNVVLFMAASTKSPNM------------------CIVMEFMSLGSLYDLL 872 Query: 1222 IKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGVARV 1401 ++ Y + +++A S+G+ +LHS IVHRD+K+ N+LLD++ N+K++DFG+ +V Sbjct: 873 GNELIPEIPYALKIKMAYQASKGMHFLHSSGIVHRDLKSLNLLLDSKWNVKVSDFGLTKV 932 Query: 1402 EAQNPKDMT--GATGTLGYMAPEVLDGKPY--NRKCDVYSFGICLWEVYCCDMPYPDLSF 1569 +++ K T GT+ ++APE+L+ DVYSFGI LWE+ + PY ++ Sbjct: 933 KSELDKKKTNDNIIGTIHWIAPEILNDSTEVDYILADVYSFGIILWELLTREQPYKGMTP 992 Query: 1570 ADVSSAVVHQNLRPDIPRCCPSA----FANIMRKCWDGNPDKRPDMDEVV 1707 A ++ +V+ +RP I +A + +++++CW + RP E++ Sbjct: 993 AAIAVSVIRDGMRPPISDEAVTAHSIEYIDLIKQCWHSDTIIRPTFLEIM 1042
>Q95UN8:M3KSL_DROME Mitogen-activated protein kinase kinase kinase - Drosophila| melanogaster (Fruit fly) Length = 1161 Score = 159 bits (401), Expect = 6e-38 Identities = 99/310 (31%), Positives = 160/310 (51%), Gaps = 12/310 (3%) Frame = +1 Query: 844 SLGPKADWEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLL-DWGEDGFATEAETTA 1020 ++G EI+ +L+I+ VI G + V+RG YDG++VA+K+ GED + Sbjct: 128 AIGDIQPHEIEYNELDIKEVIGSGGFCKVHRGYYDGEEVAIKIAHQTGED------DMQR 181 Query: 1021 LRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAG 1200 +R + QE ++ L H N+ G + T C+V+EY G Sbjct: 182 MRDNVLQEAKLFWALKHENIAALRGVCLNTK-------------------LCLVMEYARG 222 Query: 1201 GTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSR---KIVHRDVKTENMLLDT---- 1359 G+L + L K+ V+V A+ ++RG++YLH+ I+HRD+K+ N+L+ Sbjct: 223 GSLNRILAG----KIPPDVLVNWAIQIARGMNYLHNEAPMSIIHRDLKSSNVLIYEAIEG 278 Query: 1360 ----QRNLKIADFGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLW 1527 Q+ LKI DFG+AR E N + M+ A GT +M PEV+ Y++ DV+S+G+ LW Sbjct: 279 NHLQQKTLKITDFGLAR-EMYNTQRMSAA-GTYAWMPPEVISVSTYSKFSDVWSYGVLLW 336 Query: 1528 EVYCCDMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVV 1707 E+ + PY V+ V L IP+ CP + +M+ CW +P KRP E++ Sbjct: 337 ELITGETPYKGFDPLSVAYGVAVNTLTLPIPKTCPETWGALMKSCWQTDPHKRPGFKEIL 396 Query: 1708 QLMEALDTSK 1737 + +E++ SK Sbjct: 397 KQLESIACSK 406
>Q66L42:M3K10_MOUSE Mitogen-activated protein kinase kinase kinase 10 - Mus musculus| (Mouse) Length = 940 Score = 152 bits (384), Expect = 6e-36 Identities = 98/302 (32%), Positives = 155/302 (51%), Gaps = 13/302 (4%) Frame = +1 Query: 868 EIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKL--LDWGEDGFATEAETTALRTSFKQ 1041 EI +L++ +I G +G VYR + G++VAVK LD D T + +Q Sbjct: 92 EIPFHELQLEEIIGVGGFGKVYRAVWRGEEVAVKAARLDPERDPAVTAEQV-------RQ 144 Query: 1042 EVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYL 1221 E ++ L HPN+ GA + +L C+V+EY GG L + L Sbjct: 145 EARLFGALQHPNIIALRGACLSPPNL------------------CLVMEYARGGALSRVL 186 Query: 1222 IKNRRRKLAYKVVVQLALDLSRGLSYLHSRK---IVHRDVKTENML-LDTQRN------- 1368 R++ V+V A+ ++RG++YLH+ I+HRD+K+ N+L L+ N Sbjct: 187 AG---RRVPPHVLVNWAVQVARGMNYLHNDAPVPIIHRDLKSINILILEAIENHNLADTV 243 Query: 1369 LKIADFGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDM 1548 LKI DFG+AR + K A GT +MAPEV+ +++ DV+SFG+ LWE+ ++ Sbjct: 244 LKITDFGLAREWHKTTK--MSAAGTYAWMAPEVIRLSLFSKSSDVWSFGVLLWELLTGEV 301 Query: 1549 PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALD 1728 PY ++ V+ V L IP CP FA ++ +CWD +P RPD +++ +E ++ Sbjct: 302 PYREIDALAVAYGVAMNKLTLPIPSTCPEPFARLLEECWDPDPHGRPDFGSILKQLEVIE 361 Query: 1729 TS 1734 S Sbjct: 362 QS 363
>Q66HA1:M3K11_RAT Mitogen-activated protein kinase kinase kinase 11 - Rattus norvegicus| (Rat) Length = 850 Score = 152 bits (383), Expect = 7e-36 Identities = 99/304 (32%), Positives = 150/304 (49%), Gaps = 11/304 (3%) Frame = +1 Query: 850 GPKADWEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFATEAETTALRT 1029 GP +L + VI G +G VYRG++ G+ VAVK D + + Sbjct: 106 GPPPCEVASFQELRLEEVIGIGGFGKVYRGSWRGELVAVKAARQDPD-----EDISVTAE 160 Query: 1030 SFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTL 1209 S +QE ++ L+HPN+ + +L C+V+EY AGG L Sbjct: 161 SVRQEARLFAMLAHPNIIALKAVCLEEPNL------------------CLVMEYAAGGPL 202 Query: 1210 KQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIV---HRDVKTENMLL--------D 1356 + L R++ V+V A+ ++RG+ YLH +V HRD+K+ N+LL Sbjct: 203 SRALAG---RRVPPHVLVNWAVQIARGMHYLHCEALVPVIHRDLKSNNILLLQPIEGDDM 259 Query: 1357 TQRNLKIADFGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVY 1536 + LKI DFG+AR E M+ A GT +MAPEV+ +++ DV+SFG+ LWE+ Sbjct: 260 EHKTLKITDFGLAR-EWHKTTQMSAA-GTYAWMAPEVIKASTFSKGSDVWSFGVLLWELL 317 Query: 1537 CCDMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLM 1716 ++PY + V+ V L IP CP FA +M CW +P +RPD ++Q + Sbjct: 318 TGEVPYRGIDCLAVAYGVAVNKLTLPIPSTCPEPFAQLMADCWAQDPHRRPDFASILQQL 377 Query: 1717 EALD 1728 EAL+ Sbjct: 378 EALE 381
>Q80XI6:M3K11_MOUSE Mitogen-activated protein kinase kinase kinase 11 - Mus musculus| (Mouse) Length = 850 Score = 152 bits (383), Expect = 7e-36 Identities = 99/304 (32%), Positives = 150/304 (49%), Gaps = 11/304 (3%) Frame = +1 Query: 850 GPKADWEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFATEAETTALRT 1029 GP +L + VI G +G VYRG++ G+ VAVK D + + Sbjct: 106 GPPPCEVASFQELRLEEVIGIGGFGKVYRGSWRGELVAVKAARQDPD-----EDISVTAE 160 Query: 1030 SFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTL 1209 S +QE ++ L+HPN+ + +L C+V+EY AGG L Sbjct: 161 SVRQEARLFAMLAHPNIIALKAVCLEEPNL------------------CLVMEYAAGGPL 202 Query: 1210 KQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIV---HRDVKTENMLL--------D 1356 + L R++ V+V A+ ++RG+ YLH +V HRD+K+ N+LL Sbjct: 203 SRALAG---RRVPPHVLVNWAVQIARGMHYLHCEALVPVIHRDLKSNNILLLQPIEGDDM 259 Query: 1357 TQRNLKIADFGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVY 1536 + LKI DFG+AR E M+ A GT +MAPEV+ +++ DV+SFG+ LWE+ Sbjct: 260 EHKTLKITDFGLAR-EWHKTTQMSAA-GTYAWMAPEVIKASTFSKGSDVWSFGVLLWELL 317 Query: 1537 CCDMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLM 1716 ++PY + V+ V L IP CP FA +M CW +P +RPD ++Q + Sbjct: 318 TGEVPYRGIDCLAVAYGVAVNKLTLPIPSTCPEPFAQLMADCWAQDPHRRPDFASILQQL 377 Query: 1717 EALD 1728 EAL+ Sbjct: 378 EALE 381
>Q16584:M3K11_HUMAN Mitogen-activated protein kinase kinase kinase 11 - Homo sapiens| (Human) Length = 847 Score = 152 bits (383), Expect = 7e-36 Identities = 99/304 (32%), Positives = 150/304 (49%), Gaps = 11/304 (3%) Frame = +1 Query: 850 GPKADWEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFATEAETTALRT 1029 GP +L + VI G +G VYRG++ G+ VAVK D + + Sbjct: 105 GPPPCEVASFQELRLEEVIGIGGFGKVYRGSWRGELVAVKAARQDPD-----EDISVTAE 159 Query: 1030 SFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTL 1209 S +QE ++ L+HPN+ + +L C+V+EY AGG L Sbjct: 160 SVRQEARLFAMLAHPNIIALKAVCLEEPNL------------------CLVMEYAAGGPL 201 Query: 1210 KQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIV---HRDVKTENMLL--------D 1356 + L R++ V+V A+ ++RG+ YLH +V HRD+K+ N+LL Sbjct: 202 SRALAG---RRVPPHVLVNWAVQIARGMHYLHCEALVPVIHRDLKSNNILLLQPIESDDM 258 Query: 1357 TQRNLKIADFGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVY 1536 + LKI DFG+AR E M+ A GT +MAPEV+ +++ DV+SFG+ LWE+ Sbjct: 259 EHKTLKITDFGLAR-EWHKTTQMSAA-GTYAWMAPEVIKASTFSKGSDVWSFGVLLWELL 316 Query: 1537 CCDMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLM 1716 ++PY + V+ V L IP CP FA +M CW +P +RPD ++Q + Sbjct: 317 TGEVPYRGIDCLAVAYGVAVNKLTLPIPSTCPEPFAQLMADCWAQDPHRRPDFASILQQL 376 Query: 1717 EALD 1728 EAL+ Sbjct: 377 EALE 380
>Q02779:M3K10_HUMAN Mitogen-activated protein kinase kinase kinase 10 - Homo sapiens| (Human) Length = 954 Score = 150 bits (379), Expect = 2e-35 Identities = 98/302 (32%), Positives = 154/302 (50%), Gaps = 13/302 (4%) Frame = +1 Query: 868 EIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKL--LDWGEDGFATEAETTALRTSFKQ 1041 EI +L++ +I G +G VYR + G++VAVK LD +D T + Q Sbjct: 92 EIPFHELQLEEIIGVGGFGKVYRALWRGEEVAVKAARLDPEKDPAVTAEQVC-------Q 144 Query: 1042 EVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYL 1221 E ++ L HPN+ GA + L C+V+EY GG L + L Sbjct: 145 EARLFGALQHPNIIALRGACLNPPHL------------------CLVMEYARGGALSRVL 186 Query: 1222 IKNRRRKLAYKVVVQLALDLSRGLSYLHSRK---IVHRDVKTENML-LDTQRN------- 1368 R++ V+V A+ ++RG++YLH+ I+HRD+K+ N+L L+ N Sbjct: 187 AG---RRVPPHVLVNWAVQVARGMNYLHNDAPVPIIHRDLKSINILILEAIENHNLADTV 243 Query: 1369 LKIADFGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDM 1548 LKI DFG+AR + K A GT +MAPEV+ +++ DV+SFG+ LWE+ ++ Sbjct: 244 LKITDFGLAREWHKTTK--MSAAGTYAWMAPEVIRLSLFSKSSDVWSFGVLLWELLTGEV 301 Query: 1549 PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALD 1728 PY ++ V+ V L IP CP FA ++ +CWD +P RPD +++ +E ++ Sbjct: 302 PYREIDALAVAYGVAMNKLTLPIPSTCPEPFARLLEECWDPDPHGRPDFGSILKRLEVIE 361 Query: 1729 TS 1734 S Sbjct: 362 QS 363
>P41243:MATK_RAT Megakaryocyte-associated tyrosine-protein kinase - Rattus norvegicus| (Rat) Length = 467 Score = 149 bits (377), Expect = 4e-35 Identities = 102/344 (29%), Positives = 169/344 (49%), Gaps = 1/344 (0%) Frame = +1 Query: 775 DLTSLDIQLEQQLNKKWSKSNIKSLGPKADWEIDLAKLEIRHVIAQGTYGTVYRGTYDGQ 954 D ++ +L + K+ +KS + L KA W +DL L + I +G +G V +G Y GQ Sbjct: 158 DKGAICTKLVKPKRKQGAKSAEEELA-KAGWLLDLQHLTLGAQIGEGEFGAVLQGEYLGQ 216 Query: 955 QVAVKLLDWGEDGFATEAETTALRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVN 1134 +VAVK + + + TA +F E AV KL H N+ + +G + Sbjct: 217 KVAVKNI---------KCDVTA--QAFLDETAVMTKLQHRNLVRLLGVILH--------- 256 Query: 1135 DNGARANLPARACCVVVEYLAGGTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRK 1314 +V+E+++ G L +L R ++ ++Q AL ++ G+ YL S+K Sbjct: 257 ----------HGLYIVMEHVSKGNLVNFLRTRGRALVSTSQLLQFALHVAEGMEYLESKK 306 Query: 1315 IVHRDVKTENMLLDTQRNLKIADFGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRK 1494 +VHRD+ N+L+ K++DFG+A+ E + K + + + + APE L ++ K Sbjct: 307 LVHRDLAARNILVSEDLVAKVSDFGLAKAELR--KGLDSSRLPVKWTAPEALKNGRFSSK 364 Query: 1495 CDVYSFGICLWEVYCCD-MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDG 1671 DV+SFG+ LWEV+ PYP +S +VS A V + R + P CP +M CW+ Sbjct: 365 SDVWSFGVLLWEVFSYGRAPYPKMSLKEVSEA-VEKGYRMEPPDSCPGPVHTLMGSCWEA 423 Query: 1672 NPDKRPDMDEVVQLMEALDTSKGGGMIPDGQSSGCLCFTRARGP 1803 P +RP ++V+ + S G GQ + TR++ P Sbjct: 424 EPSRRPPFRKIVEKLGRELRSVGVAAPAGGQEAEGSAPTRSQDP 467
>P83104:M3LK7_DROME Putative mitogen-activated protein kinase kinase kinase 7-like -| Drosophila melanogaster (Fruit fly) Length = 393 Score = 148 bits (374), Expect = 8e-35 Identities = 99/294 (33%), Positives = 151/294 (51%), Gaps = 11/294 (3%) Frame = +1 Query: 868 EIDLAKLEIRH-VIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFATEAETTALRTSFKQE 1044 ++D A++++ + G+ G V + T+ Q++AVK+ D+ E+ AE +E Sbjct: 4 QVDFAEVKLSEKFLGAGSGGAVRKATFQNQEIAVKIFDFLEETIKKNAE---------RE 54 Query: 1045 VAVWHKLSHPNVTKFVG-ASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYL 1221 + ++ H NV + +G AS G D +++EYL G+L YL Sbjct: 55 ITHLSEIDHENVIRVIGRASNGKKDY-------------------LLMEYLEEGSLHNYL 95 Query: 1222 IKNRRRKLAYKVVVQLALDLSRGLSYLHS--RKIVHRDVKTENMLLDTQR-NLKIADFGV 1392 + + + + V+ AL ++ L+YLHS R IVHRD+K +NMLL Q +LKI DFG+ Sbjct: 96 YGDDKWEYTVEQAVRWALQCAKALAYLHSLDRPIVHRDIKPQNMLLYNQHEDLKICDFGL 155 Query: 1393 ARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDMPY-----P 1557 A + N DM G TL YMAPE + Y KCDVYSFGI LWE+ +PY P Sbjct: 156 ATDMSNNKTDMQG---TLRYMAPEAIKHLKYTAKCDVYSFGIMLWELMTRQLPYSHLENP 212 Query: 1558 DLSFADVSSAVVHQNLRPDIPRC-CPSAFANIMRKCWDGNPDKRPDMDEVVQLM 1716 + +A + + + L + R CP +M C D NP+KRP M E+ + + Sbjct: 213 NSQYAIMKAISSGEKLPMEAVRSDCPEGIKQLMECCMDINPEKRPSMKEIEKFL 266
>P41242:MATK_MOUSE Megakaryocyte-associated tyrosine-protein kinase - Mus musculus| (Mouse) Length = 505 Score = 148 bits (373), Expect = 1e-34 Identities = 102/344 (29%), Positives = 169/344 (49%), Gaps = 1/344 (0%) Frame = +1 Query: 775 DLTSLDIQLEQQLNKKWSKSNIKSLGPKADWEIDLAKLEIRHVIAQGTYGTVYRGTYDGQ 954 D ++ +L + K+ +KS + L KA W +DL L + I +G +G V +G Y GQ Sbjct: 197 DKGAICTKLVKPRRKQGAKSAEEELA-KAGWLLDLQHLTLGAQIGEGEFGAVLQGEYLGQ 255 Query: 955 QVAVKLLDWGEDGFATEAETTALRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVN 1134 +VAVK + + + TA +F E AV KL H N+ + +G + Sbjct: 256 KVAVKNI---------KCDVTA--QAFLDETAVMTKLQHRNLVRLLGVILH--------- 295 Query: 1135 DNGARANLPARACCVVVEYLAGGTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRK 1314 +V+E+++ G L +L R ++ ++Q AL ++ G+ YL S+K Sbjct: 296 ----------HGLYIVMEHVSKGNLVNFLRTRGRALVSTSQLLQFALHVAEGMEYLESKK 345 Query: 1315 IVHRDVKTENMLLDTQRNLKIADFGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRK 1494 +VHRD+ N+L+ K++DFG+A+ E K + + + + APE L ++ K Sbjct: 346 LVHRDLAARNILVSEDLVAKVSDFGLAKAER---KGLDSSRLPVKWTAPEALKNGRFSSK 402 Query: 1495 CDVYSFGICLWEVYCCD-MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDG 1671 DV+SFG+ LWEV+ PYP +S +VS A V + R + P CP + +M CW+ Sbjct: 403 SDVWSFGVLLWEVFSYGRAPYPKMSLKEVSEA-VEKGYRMEPPDGCPGSVHTLMGSCWEA 461 Query: 1672 NPDKRPDMDEVVQLMEALDTSKGGGMIPDGQSSGCLCFTRARGP 1803 P +RP ++V+ + S G GQ + TR++ P Sbjct: 462 EPARRPPFRKIVEKLGRELRSVGVSAPAGGQEAEGSAPTRSQDP 505
>Q5TCX8:M3KL4_HUMAN Mitogen-activated protein kinase kinase kinase - Homo sapiens (Human)| Length = 1036 Score = 145 bits (365), Expect = 9e-34 Identities = 92/315 (29%), Positives = 152/315 (48%), Gaps = 23/315 (7%) Frame = +1 Query: 853 PKADWEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFATEAETTALRTS 1032 P + + +LE++ +I G +G VYR T+ GQ+VAVK E + A S Sbjct: 113 PSSPVHVAFERLELKELIGAGGFGQVYRATWQGQEVAVKAARQDP-----EQDAAAAAES 167 Query: 1033 FKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLK 1212 ++E ++ L HPN+ + G + L C+V+E+ GG L Sbjct: 168 VRREARLFAMLRHPNIIELRGVCLQQPHL------------------CLVLEFARGGALN 209 Query: 1213 QYLIK------------NRRRKLAYKVVVQLALDLSRGLSYLHSRK---IVHRDVKTENM 1347 + L R R++ V+V A+ ++RG+ YLH I+HRD+K+ N+ Sbjct: 210 RALAAANAAPDPRAPGPRRARRIPPHVLVNWAVQIARGMLYLHEEAFVPILHRDLKSSNI 269 Query: 1348 LLDTQ--------RNLKIADFGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDV 1503 LL + + LKI DFG+AR + K T GT +MAPEV+ +++ D+ Sbjct: 270 LLLEKIEHDDICNKTLKITDFGLAREWHRTTKMSTA--GTYAWMAPEVIKSSLFSKGSDI 327 Query: 1504 YSFGICLWEVYCCDMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDK 1683 +S+G+ LWE+ ++PY + V+ V L IP CP FA +M++CW +P Sbjct: 328 WSYGVLLWELLTGEVPYRGIDGLAVAYGVAVNKLTLPIPSTCPEPFAKLMKECWQQDPHI 387 Query: 1684 RPDMDEVVQLMEALD 1728 RP +++ + A++ Sbjct: 388 RPSFALILEQLTAIE 402
>P18161:KYK2_DICDI Tyrosine-protein kinase 2 - Dictyostelium discoideum (Slime mold)| Length = 410 Score = 145 bits (365), Expect = 9e-34 Identities = 91/339 (26%), Positives = 163/339 (48%), Gaps = 8/339 (2%) Frame = +1 Query: 766 DKIDLTSLDIQLEQQLNKKWSKSNIKSLGPKADWEIDLAKLEIRHVIAQGTYGTVYRGTY 945 +K L + +E + KK +KS+ + ++ ID+ ++ + +G + V+ G + Sbjct: 68 NKESLNDIQRAIESEKIKKTKFEELKSILGEREYIIDINDIQFIQKVGEGAFSEVWEGWW 127 Query: 946 DGQQVAVKLLDWGEDGFATEAETTALRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKI 1125 G VA+K L + + F +EV K +H N+ F+GA Sbjct: 128 KGIHVAIKKLK-------IIGDEEQFKERFIREVQNLKKGNHQNIVMFIGACY------- 173 Query: 1126 PVNDNGARANLPARACCVVVEYLAGGTLKQYL----IKNRRRKLAYKVVVQLALDLSRGL 1293 + C++ EY+AGG+L L + K ++ +V+++A D++ GL Sbjct: 174 -------------KPACIITEYMAGGSLYNILHNPNSSTPKVKYSFPLVLKMATDMALGL 220 Query: 1294 SYLHSRKIVHRDVKTENMLLDTQRNLKIADFGVARVEAQNPKDMTGATGTL---GYMAPE 1464 +LHS IVHRD+ ++N+LLD N+KI+DFG++ E MT G + + PE Sbjct: 221 LHLHSITIVHRDLTSQNILLDELGNIKISDFGLS-AEKSREGSMTMTNGGICNPRWRPPE 279 Query: 1465 VLDGKP-YNRKCDVYSFGICLWEVYCCDMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAF 1641 + Y+ K DVY F + +WE+ ++P+ DL + S+ V + LRP IP C Sbjct: 280 LTKNLGHYSEKVDVYCFSLVVWEILTGEIPFSDLDGSQRSAQVAYAGLRPPIPEYCDPEL 339 Query: 1642 ANIMRKCWDGNPDKRPDMDEVVQLMEALDTSKGGGMIPD 1758 ++ +CW+ +P+ RP +V ++ + + G + D Sbjct: 340 KLLLTQCWEADPNDRPPFTYIVNKLKEISWNNPIGFVSD 378
>Q9ESL4:MLTK_MOUSE Mitogen-activated protein kinase kinase kinase MLT - Mus musculus| (Mouse) Length = 802 Score = 143 bits (360), Expect = 3e-33 Identities = 82/276 (29%), Positives = 138/276 (50%), Gaps = 5/276 (1%) Frame = +1 Query: 913 GTYGTVYRGTYDGQ--QVAVKLLDWGEDGFATEAETTALRTSFKQEVAVWHKLSHPNVTK 1086 G++G+VYR + Q +VAVK L ++E + LSH N+ + Sbjct: 25 GSFGSVYRAKWISQDKEVAVKKL-----------------LKIEKEAEILSVLSHRNIIQ 67 Query: 1087 FVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYLIKNRRRKLAYKVVVQ 1266 F G + + I V EY + G+L Y+ NR ++ + ++ Sbjct: 68 FYGVILEPPNYGI------------------VTEYASLGSLYDYINSNRSEEMDMEHIMT 109 Query: 1267 LALDLSRGLSYLHSR---KIVHRDVKTENMLLDTQRNLKIADFGVARVEAQNPKDMTGAT 1437 A D+++G+ YLH K++HRD+K+ N+++ LKI DFG +R N Sbjct: 110 WATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASRFH--NHTTHMSLV 167 Query: 1438 GTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDMPYPDLSFADVSSAVVHQNLRPDI 1617 GT +MAPEV+ P + CD YS+G+ LWE+ ++P+ L V+ VV +N R I Sbjct: 168 GTFPWMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAWLVVEKNERLTI 227 Query: 1618 PRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 P CP +FA ++ +CW+ + KRP +++ ++E++ Sbjct: 228 PSSCPRSFAELLHQCWEADAKKRPSFKQIISILESM 263
>Q9NYL2:MLTK_HUMAN Mitogen-activated protein kinase kinase kinase MLT - Homo sapiens| (Human) Length = 800 Score = 143 bits (360), Expect = 3e-33 Identities = 85/281 (30%), Positives = 140/281 (49%), Gaps = 7/281 (2%) Frame = +1 Query: 913 GTYGTVYRGTYDGQ--QVAVKLLDWGEDGFATEAETTALRTSFKQEVAVWHKLSHPNVTK 1086 G++G+VYR + Q +VAVK L ++E + LSH N+ + Sbjct: 25 GSFGSVYRAKWISQDKEVAVKKL-----------------LKIEKEAEILSVLSHRNIIQ 67 Query: 1087 FVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYLIKNRRRKLAYKVVVQ 1266 F G + + I V EY + G+L Y+ NR ++ ++ Sbjct: 68 FYGVILEPPNYGI------------------VTEYASLGSLYDYINSNRSEEMDMDHIMT 109 Query: 1267 LALDLSRGLSYLHSR---KIVHRDVKTENMLLDTQRNLKIADFGVARVEAQNPKDMTGAT 1437 A D+++G+ YLH K++HRD+K+ N+++ LKI DFG +R N Sbjct: 110 WATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASRFH--NHTTHMSLV 167 Query: 1438 GTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDMPYPDLSFADVSSAVVHQNLRPDI 1617 GT +MAPEV+ P + CD YS+G+ LWE+ ++P+ L V+ VV +N R I Sbjct: 168 GTFPWMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAWLVVEKNERLTI 227 Query: 1618 PRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL--DTS 1734 P CP +FA ++ +CW+ + KRP +++ ++E++ DTS Sbjct: 228 PSSCPRSFAELLHQCWEADAKKRPSFKQIISILESMSNDTS 268
>Q62073:M3K7_MOUSE Mitogen-activated protein kinase kinase kinase 7 - Mus musculus| (Mouse) Length = 579 Score = 142 bits (358), Expect = 6e-33 Identities = 93/294 (31%), Positives = 146/294 (49%), Gaps = 8/294 (2%) Frame = +1 Query: 868 EIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFATEAETTALRTSFKQEV 1047 EID ++E+ V+ +G +G V + + + VA+K + E+ + R +F E+ Sbjct: 30 EIDYKEIEVEEVVGRGAFGVVCKAKWRAKDVAIK-----------QIESESERKAFIVEL 78 Query: 1048 AVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYLIK 1227 +++HPN+ K GA + PV C+V+EY GG+L Y + Sbjct: 79 RQLSRVNHPNIVKLYGACLN------PV--------------CLVMEYAEGGSL--YNVL 116 Query: 1228 NRRRKLAYKVVVQL---ALDLSRGLSYLHS---RKIVHRDVKTENMLLDTQRN-LKIADF 1386 + L Y L S+G++YLHS + ++HRD+K N+LL LKI DF Sbjct: 117 HGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLKICDF 176 Query: 1387 GVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDMPYPDLS 1566 G A MT G+ +MAPEV +G Y+ KCDV+S+GI LWEV P+ ++ Sbjct: 177 GTA---CDIQTHMTNNKGSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPFDEIG 233 Query: 1567 F-ADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 A VH RP + + P ++M +CW +P +RP M+E+V++M L Sbjct: 234 GPAFRIMWAVHNGTRPPLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHL 287
>O43318:M3K7_HUMAN Mitogen-activated protein kinase kinase kinase 7 - Homo sapiens| (Human) Length = 606 Score = 142 bits (358), Expect = 6e-33 Identities = 93/294 (31%), Positives = 146/294 (49%), Gaps = 8/294 (2%) Frame = +1 Query: 868 EIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFATEAETTALRTSFKQEV 1047 EID ++E+ V+ +G +G V + + + VA+K + E+ + R +F E+ Sbjct: 30 EIDYKEIEVEEVVGRGAFGVVCKAKWRAKDVAIK-----------QIESESERKAFIVEL 78 Query: 1048 AVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYLIK 1227 +++HPN+ K GA + PV C+V+EY GG+L Y + Sbjct: 79 RQLSRVNHPNIVKLYGACLN------PV--------------CLVMEYAEGGSL--YNVL 116 Query: 1228 NRRRKLAYKVVVQL---ALDLSRGLSYLHS---RKIVHRDVKTENMLLDTQRN-LKIADF 1386 + L Y L S+G++YLHS + ++HRD+K N+LL LKI DF Sbjct: 117 HGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLKICDF 176 Query: 1387 GVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDMPYPDLS 1566 G A MT G+ +MAPEV +G Y+ KCDV+S+GI LWEV P+ ++ Sbjct: 177 GTA---CDIQTHMTNNKGSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPFDEIG 233 Query: 1567 F-ADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 A VH RP + + P ++M +CW +P +RP M+E+V++M L Sbjct: 234 GPAFRIMWAVHNGTRPPLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHL 287
>Q60700:M3K12_MOUSE Mitogen-activated protein kinase kinase kinase 12 - Mus musculus| (Mouse) Length = 888 Score = 142 bits (357), Expect = 7e-33 Identities = 79/281 (28%), Positives = 139/281 (49%) Frame = +1 Query: 865 WEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFATEAETTALRTSFKQE 1044 WE+ ++ + G G V+ G + G++VAVK +R + + Sbjct: 151 WEVPFEEILDLQWVGSGAQGAVFLGRFHGEEVAVK----------------KVRDLKETD 194 Query: 1045 VAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYLI 1224 + KL HPN+ F G A C+++E+ A G L Y + Sbjct: 195 IKHLRKLKHPNIITFKGVCT------------------QAPCYCILMEFCAQGQL--YEV 234 Query: 1225 KNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGVARVE 1404 R + ++V ++ ++ G++YLH KI+HRD+K+ NML+ +KI+DFG ++ Sbjct: 235 LRAGRPVTPSLLVDWSMGIAGGMNYLHLHKIIHRDLKSPNMLITYDDVVKISDFGTSKEL 294 Query: 1405 AQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDMPYPDLSFADVSS 1584 + M+ A GT+ +MAPEV+ +P + K D++SFG+ LWE+ ++PY D+ + + Sbjct: 295 SDKSTKMSFA-GTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSAIIW 353 Query: 1585 AVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVV 1707 V +L +P CP F ++R+CW+ P RP +++ Sbjct: 354 GVGSNSLHLPVPSSCPDGFKILLRQCWNSKPRNRPSFRQIL 394
>Q12852:M3K12_HUMAN Mitogen-activated protein kinase kinase kinase 12 - Homo sapiens| (Human) Length = 859 Score = 142 bits (357), Expect = 7e-33 Identities = 79/281 (28%), Positives = 139/281 (49%) Frame = +1 Query: 865 WEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFATEAETTALRTSFKQE 1044 WE+ ++ + G G V+ G + G++VAVK +R + + Sbjct: 118 WEVPFEEILDLQWVGSGAQGAVFLGRFHGEEVAVK----------------KVRDLKETD 161 Query: 1045 VAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYLI 1224 + KL HPN+ F G A C+++E+ A G L Y + Sbjct: 162 IKHLRKLKHPNIITFKGVCT------------------QAPCYCILMEFCAQGQL--YEV 201 Query: 1225 KNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGVARVE 1404 R + ++V ++ ++ G++YLH KI+HRD+K+ NML+ +KI+DFG ++ Sbjct: 202 LRAGRPVTPSLLVDWSMGIAGGMNYLHLHKIIHRDLKSPNMLITYDDVVKISDFGTSKEL 261 Query: 1405 AQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDMPYPDLSFADVSS 1584 + M+ A GT+ +MAPEV+ +P + K D++SFG+ LWE+ ++PY D+ + + Sbjct: 262 SDKSTKMSFA-GTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSAIIW 320 Query: 1585 AVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVV 1707 V +L +P CP F ++R+CW+ P RP +++ Sbjct: 321 GVGSNSLHLPVPSSCPDGFKILLRQCWNSKPRNRPSFRQIL 361
>P80192:M3K9_HUMAN Mitogen-activated protein kinase kinase kinase 9 - Homo sapiens| (Human) Length = 1104 Score = 141 bits (355), Expect = 1e-32 Identities = 89/300 (29%), Positives = 146/300 (48%), Gaps = 11/300 (3%) Frame = +1 Query: 868 EIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFATEAETTALRTSFKQEV 1047 EID A+L + +I G +G VYR + G +VAVK D + + + +QE Sbjct: 138 EIDFAELTLEEIIGIGGFGKVYRAFWIGDEVAVKAARHDPD-----EDISQTIENVRQEA 192 Query: 1048 AVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYLIK 1227 ++ L HPN+ G + +L C+V+E+ GG L + L Sbjct: 193 KLFAMLKHPNIIALRGVCLKEPNL------------------CLVMEFARGGPLNRVLSG 234 Query: 1228 NRRRKLAYKVVVQLALDLSRGLSYLHSRKIV---HRDVKTENMLLD--------TQRNLK 1374 R + ++V A+ ++RG++YLH IV HRD+K+ N+L+ + + LK Sbjct: 235 KR---IPPDILVNWAVQIARGMNYLHDEAIVPIIHRDLKSSNILILQKVENGDLSNKILK 291 Query: 1375 IADFGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDMPY 1554 I DFG+AR + K A GT +MAPEV+ +++ DV+S+G+ LWE+ ++P+ Sbjct: 292 ITDFGLAREWHRTTK--MSAAGTYAWMAPEVIRASMFSKGSDVWSYGVLLWELLTGEVPF 349 Query: 1555 PDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDTS 1734 + V+ V L IP CP FA +M CW+ +P RP ++ + ++ S Sbjct: 350 RGIDGLAVAYGVAMNKLALPIPSTCPEPFAKLMEDCWNPDPHSRPSFTNILDQLTTIEES 409
>Q63796:M3K12_RAT Mitogen-activated protein kinase kinase kinase 12 - Rattus norvegicus| (Rat) Length = 888 Score = 141 bits (355), Expect = 1e-32 Identities = 79/281 (28%), Positives = 139/281 (49%) Frame = +1 Query: 865 WEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFATEAETTALRTSFKQE 1044 WE+ ++ + G G V+ G + G++VAVK +R + + Sbjct: 151 WEVPFEEILDLQWVGSGAQGAVFLGRFHGEEVAVK----------------KVRDLKETD 194 Query: 1045 VAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYLI 1224 + KL HPN+ F G A C+++E+ A G L Y + Sbjct: 195 IKHLRKLKHPNIITFKGVCT------------------QAPCYCILMEFCAQGQL--YEV 234 Query: 1225 KNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGVARVE 1404 R + ++V ++ ++ G++YLH KI+HRD+K+ NML+ +KI+DFG ++ Sbjct: 235 LRAGRPVTPSLLVDWSMGIAGGMNYLHLHKIIHRDLKSPNMLITYDDVVKISDFGTSKEL 294 Query: 1405 AQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDMPYPDLSFADVSS 1584 + M+ A GT+ +MAPEV+ +P + K D++SFG+ LWE+ ++PY D+ + + Sbjct: 295 SDKSTKMSFA-GTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSAIIW 353 Query: 1585 AVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVV 1707 V +L +P CP F ++R+CW+ P RP +++ Sbjct: 354 GVGSNSLHLPVPSSCPDGFKILLRQCWNRKPRNRPSFRQIL 394
>Q59H18:TNI3K_HUMAN Serine/threonine-protein kinase TNNI3K - Homo sapiens (Human)| Length = 936 Score = 140 bits (353), Expect = 2e-32 Identities = 92/332 (27%), Positives = 174/332 (52%), Gaps = 14/332 (4%) Frame = +1 Query: 850 GPKADWEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFATEAETTALRT 1029 G + + + L+++E +I G++G VY+G + VA+K + + + ++++ Sbjct: 552 GLPSHFHLQLSEIEFHEIIGSGSFGKVYKGRCRNKIVAIKR--YRANTYCSKSDVDM--- 606 Query: 1030 SFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTL 1209 F +EV++ +L+HP V +FVGA + ND A +V +Y++GG+L Sbjct: 607 -FCREVSILCQLNHPCVIQFVGACL---------NDPSQFA--------IVTQYISGGSL 648 Query: 1210 KQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHS--RKIVHRDVKTENMLLDTQRNLKIAD 1383 L+ ++R L + + +A+D+++G+ YLH+ + I+HRD+ + N+LL + +AD Sbjct: 649 FS-LLHEQKRILDLQSKLIIAVDVAKGMEYLHNLTQPIIHRDLNSHNILLYEDGHAVVAD 707 Query: 1384 FGVAR-VEAQNPKDMTGATGTLGYMAPEVLDG-KPYNRKCDVYSFGICLWEVYCCDMPYP 1557 FG +R +++ + +MT G L +MAPEV Y K DV+S+ +CLWE+ ++P+ Sbjct: 708 FGESRFLQSLDEDNMTKQPGNLRWMAPEVFTQCTRYTIKADVFSYALCLWEILTGEIPFA 767 Query: 1558 DLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVV---------- 1707 L A ++ + + ++RP I P ++++ + W+ P+ RP+ EVV Sbjct: 768 HLKPAAAAADMAYHHIRPPIGYSIPKPISSLLIRGWNACPEGRPEFSEVVMKLEECLCNI 827 Query: 1708 QLMEALDTSKGGGMIPDGQSSGCLCFTRARGP 1803 +LM ++ G + P S C GP Sbjct: 828 ELMSPASSNSSGSLSPSSSSD---CLVNRGGP 856
>Q3U1V8:M3K9_MOUSE Mitogen-activated protein kinase kinase kinase 9 - Mus musculus| (Mouse) Length = 1077 Score = 140 bits (352), Expect = 3e-32 Identities = 88/300 (29%), Positives = 146/300 (48%), Gaps = 11/300 (3%) Frame = +1 Query: 868 EIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFATEAETTALRTSFKQEV 1047 EID A+L + +I G +G VYR + G +VAVK D + + + +QE Sbjct: 131 EIDFAELTLEEIIGIGGFGKVYRAFWAGDEVAVKAARHDPD-----EDISQTIENVRQEA 185 Query: 1048 AVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYLIK 1227 ++ L HPN+ G + +L C+V+E+ GG L + L Sbjct: 186 KLFAMLKHPNIIALRGVCLKEPNL------------------CLVMEFARGGPLNRVLSG 227 Query: 1228 NRRRKLAYKVVVQLALDLSRGLSYLHSRKIV---HRDVKTENMLLD--------TQRNLK 1374 R + ++V A+ ++RG++YLH IV HRD+K+ N+L+ + + L+ Sbjct: 228 KR---IPPDILVNWAVQIARGMNYLHDEAIVPIIHRDLKSSNILILQKVENGDLSNKILE 284 Query: 1375 IADFGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDMPY 1554 I DFG+AR + K A GT +MAPEV+ +++ DV+S+G+ LWE+ ++P+ Sbjct: 285 ITDFGLAREWHRTTK--MSAAGTYAWMAPEVIRASMFSKGSDVWSYGVLLWELLTGEVPF 342 Query: 1555 PDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDTS 1734 + V+ V L IP CP FA +M CW+ +P RP ++ + ++ S Sbjct: 343 RGIDGLAVAYGVAMNKLALPIPSTCPEPFAKLMEDCWNPDPHSRPSFTSILDQLTTIEES 402
>Q7T2V3:M3K10_XENLA Mitogen-activated protein kinase kinase kinase 10 - Xenopus laevis| (African clawed frog) Length = 1005 Score = 140 bits (352), Expect = 3e-32 Identities = 89/300 (29%), Positives = 148/300 (49%), Gaps = 11/300 (3%) Frame = +1 Query: 868 EIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFATEAETTALRTSFKQEV 1047 EI+ +L + +I G +G VY+G + ++VAVK + D + + +QE Sbjct: 112 EIEFDELNLDEIIGVGGFGKVYKGLWRDEEVAVKAVRHDPD-----EDINVTAENVRQEA 166 Query: 1048 AVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYLIK 1227 ++ L HPN+ G + L C+V+EY GG L + L Sbjct: 167 KIFCMLCHPNIIALTGVCLKPPHL------------------CLVMEYARGGPLHRALAG 208 Query: 1228 NRRRKLAYKVVVQLALDLSRGLSYLHSRKIV---HRDVKTENMLLDTQ--------RNLK 1374 +K+ V+V A+ +++G++YLH+ IV HRD+ + N+L+ + + L Sbjct: 209 ---KKVPAHVLVNWAVQIAKGMTYLHNEAIVPIIHRDLGSSNILILEKAENDDLFNKTLN 265 Query: 1375 IADFGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDMPY 1554 I DFG+AR E Q M+ A GT +MAPEV+ +++ DV+SFG+ LWE+ ++PY Sbjct: 266 ITDFGLAR-EWQKTTKMSAA-GTYAWMAPEVIRLSLFSKSSDVWSFGVLLWELLTGEVPY 323 Query: 1555 PDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDTS 1734 ++ V+ V L IP CP F I+ CWD +P RP +++ + ++ S Sbjct: 324 REIDALAVAYGVAMNKLTLPIPSTCPEPFVRILEACWDPDPHSRPTFSCILEQLTTIEQS 383
>Q5GIG6:TNI3K_MOUSE Serine/threonine-protein kinase TNNI3K - Mus musculus (Mouse)| Length = 834 Score = 139 bits (350), Expect = 5e-32 Identities = 88/318 (27%), Positives = 169/318 (53%), Gaps = 13/318 (4%) Frame = +1 Query: 865 WEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFATEAETTALRTSFKQE 1044 + + L+++E +I G++G VY+G + VA+K + + + ++++ F +E Sbjct: 455 FHLQLSEIEFHEIIGSGSFGKVYKGRCRNKIVAIKR--YRANTYCSKSDVDM----FCRE 508 Query: 1045 VAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYLI 1224 V++ +L+HP V +FVGA + +V +Y++GG+L L+ Sbjct: 509 VSILCQLNHPCVVQFVGACLDDPS-----------------QFAIVTQYISGGSLFS-LL 550 Query: 1225 KNRRRKLAYKVVVQLALDLSRGLSYLHS--RKIVHRDVKTENMLLDTQRNLKIADFGVAR 1398 ++R L + + +A+D+++G+ YLHS + I+HRD+ + N+LL + +ADFG +R Sbjct: 551 HEQKRILDLQSKLIIAVDVAKGMEYLHSLTQPIIHRDLNSHNILLYEDGHAVVADFGESR 610 Query: 1399 -VEAQNPKDMTGATGTLGYMAPEVLDG-KPYNRKCDVYSFGICLWEVYCCDMPYPDLSFA 1572 +++ + +MT G L +MAPEV Y K DV+S+ +CLWE+ ++P+ L A Sbjct: 611 FLQSLDEDNMTKQPGNLRWMAPEVFTQCTRYTIKADVFSYALCLWELLIGEIPFAHLKPA 670 Query: 1573 DVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME---------AL 1725 ++ + + ++RP I P ++++ + W+ P+ RP+ EVV+ +E + Sbjct: 671 AAAADMAYHHIRPPIGYSIPKPISSLLMRGWNACPEGRPEFSEVVRKLEECLCNVELMSP 730 Query: 1726 DTSKGGGMIPDGQSSGCL 1779 +S G + SS CL Sbjct: 731 ASSNSSGSLSPSSSSDCL 748
>Q1HKZ5:M3K13_MOUSE Mitogen-activated protein kinase kinase kinase 13 - Mus musculus| (Mouse) Length = 959 Score = 138 bits (348), Expect = 8e-32 Identities = 77/285 (27%), Positives = 138/285 (48%) Frame = +1 Query: 865 WEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFATEAETTALRTSFKQE 1044 WE+ ++ + G G V+ G + ++VA+K +R + + Sbjct: 160 WEVPFEEISELQWLGSGAQGAVFLGKFRAEEVAIK----------------KVREQNETD 203 Query: 1045 VAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYLI 1224 + KL HPN+ F G A C+++EY A G L Y + Sbjct: 204 IKHLRKLKHPNIIAFKGVCT------------------QAPCYCIIMEYCAHGQL--YEV 243 Query: 1225 KNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGVARVE 1404 RK+ +++V + ++ G++YLH KI+HRD+K+ N+L+ +KI+DFG ++ Sbjct: 244 LRAGRKITPRLLVDWSTGIASGMNYLHLHKIIHRDLKSPNVLVTHTDAVKISDFGTSKEL 303 Query: 1405 AQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDMPYPDLSFADVSS 1584 + M+ A GT+ +MAPEV+ +P + K D++SFG+ LWE+ ++PY D+ + + Sbjct: 304 SDKSTKMSFA-GTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSAIIW 362 Query: 1585 AVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 1719 V +L +P CP F +M++ W P RP + + ++ Sbjct: 363 GVGSNSLHLPVPSTCPDGFKILMKQTWQSKPRNRPSFRQTLMHLD 407
>O43283:M3K13_HUMAN Mitogen-activated protein kinase kinase kinase 13 - Homo sapiens| (Human) Length = 966 Score = 138 bits (348), Expect = 8e-32 Identities = 77/285 (27%), Positives = 138/285 (48%) Frame = +1 Query: 865 WEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFATEAETTALRTSFKQE 1044 WE+ ++ + G G V+ G + ++VA+K +R + + Sbjct: 161 WEVPFEEISELQWLGSGAQGAVFLGKFRAEEVAIK----------------KVREQNETD 204 Query: 1045 VAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYLI 1224 + KL HPN+ F G A C+++EY A G L Y + Sbjct: 205 IKHLRKLKHPNIIAFKGVCT------------------QAPCYCIIMEYCAHGQL--YEV 244 Query: 1225 KNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGVARVE 1404 RK+ +++V + ++ G++YLH KI+HRD+K+ N+L+ +KI+DFG ++ Sbjct: 245 LRAGRKITPRLLVDWSTGIASGMNYLHLHKIIHRDLKSPNVLVTHTDAVKISDFGTSKEL 304 Query: 1405 AQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDMPYPDLSFADVSS 1584 + M+ A GT+ +MAPEV+ +P + K D++SFG+ LWE+ ++PY D+ + + Sbjct: 305 SDKSTKMSFA-GTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSAIIW 363 Query: 1585 AVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 1719 V +L +P CP F +M++ W P RP + + ++ Sbjct: 364 GVGSNSLHLPVPSTCPDGFKILMKQTWQSKPRNRPSFRQTLMHLD 408
>Q7TQP6:TNI3K_RAT Serine/threonine-protein kinase TNNI3K - Rattus norvegicus (Rat)| Length = 835 Score = 138 bits (347), Expect = 1e-31 Identities = 88/318 (27%), Positives = 168/318 (52%), Gaps = 13/318 (4%) Frame = +1 Query: 865 WEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFATEAETTALRTSFKQE 1044 + + L+++E +I G++G VY+G + VA+K + + + ++++ F +E Sbjct: 456 FHLQLSEIEFHEIIGSGSFGKVYKGRCRNKIVAIKR--YRANTYCSKSDVDM----FCRE 509 Query: 1045 VAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYLI 1224 V++ +L+HP V +FVGA + +V +Y++GG+L L+ Sbjct: 510 VSILCQLNHPCVVQFVGACLDDPS-----------------QFAIVTQYISGGSLFS-LL 551 Query: 1225 KNRRRKLAYKVVVQLALDLSRGLSYLHS--RKIVHRDVKTENMLLDTQRNLKIADFGVAR 1398 ++R L + + +A+D+++G+ YLHS + I+HRD+ + N+LL + +ADFG +R Sbjct: 552 HEQKRILDLQSKLIIAVDVAKGMEYLHSLTQPIIHRDLNSHNILLYEDGHAVVADFGESR 611 Query: 1399 -VEAQNPKDMTGATGTLGYMAPEVLDG-KPYNRKCDVYSFGICLWEVYCCDMPYPDLSFA 1572 +++ + +MT G L +MAPEV Y K DV+S+ +CLWE+ ++P+ L A Sbjct: 612 FLQSLDEDNMTKQPGNLRWMAPEVFTQCTRYTIKADVFSYSLCLWELLTGEIPFAHLKPA 671 Query: 1573 DVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME---------AL 1725 ++ + + ++RP I P ++++ + W+ P+ RP+ EVV +E + Sbjct: 672 AAAADMAYHHIRPPIGYSIPKPISSLLIRGWNACPEGRPEFSEVVSKLEECLCNVELMSP 731 Query: 1726 DTSKGGGMIPDGQSSGCL 1779 +S G + SS CL Sbjct: 732 ASSNSSGSLSPSSSSDCL 749
>P42679:MATK_HUMAN Megakaryocyte-associated tyrosine-protein kinase - Homo sapiens| (Human) Length = 507 Score = 137 bits (346), Expect = 1e-31 Identities = 98/352 (27%), Positives = 166/352 (47%), Gaps = 1/352 (0%) Frame = +1 Query: 751 DYVRADKIDLTSLDIQLEQQLNKKWSKSNIKSLGPKADWEIDLAKLEIRHVIAQGTYGTV 930 D V D ++ +L + K +KS + L +A W ++L L + I +G +G V Sbjct: 191 DMVEHYSKDKGAICTKLVRPKRKHGTKSAEEELA-RAGWLLNLQHLTLGAQIGEGEFGAV 249 Query: 931 YRGTYDGQQVAVKLLDWGEDGFATEAETTALRTSFKQEVAVWHKLSHPNVTKFVGASMGT 1110 +G Y GQ+VAVK + + + TA +F E AV K+ H N+ + +G + Sbjct: 250 LQGEYLGQKVAVKNI---------KCDVTA--QAFLDETAVMTKMQHENLVRLLGVILH- 297 Query: 1111 TDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYLIKNRRRKLAYKVVVQLALDLSRG 1290 + +V+E+++ G L +L R + ++Q +L ++ G Sbjct: 298 ------------------QGLYIVMEHVSKGNLVNFLRTRGRALVNTAQLLQFSLHVAEG 339 Query: 1291 LSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGVARVEAQNPKDMTGATGTLGYMAPEVL 1470 + YL S+K+VHRD+ N+L+ K++DFG+A+ E K + + + + APE L Sbjct: 340 MEYLESKKLVHRDLAARNILVSEDLVAKVSDFGLAKAER---KGLDSSRLPVKWTAPEAL 396 Query: 1471 DGKPYNRKCDVYSFGICLWEVYCCD-MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFAN 1647 + K DV+SFG+ LWEV+ PYP +S +VS A V + R + P CP Sbjct: 397 KHGKFTSKSDVWSFGVLLWEVFSYGRAPYPKMSLKEVSEA-VEKGYRMEPPEGCPGPVHV 455 Query: 1648 IMRKCWDGNPDKRPDMDEVVQLMEALDTSKGGGMIPDGQSSGCLCFTRARGP 1803 +M CW+ P +RP ++ + + S G GQ + R++ P Sbjct: 456 LMSSCWEAEPARRPPFRKLAEKLARELRSAGAPASVSGQDADGSTSPRSQEP 507
>Q5R8X7:M3K13_PONPY Mitogen-activated protein kinase kinase kinase 13 - Pongo pygmaeus| (Orangutan) Length = 966 Score = 137 bits (345), Expect = 2e-31 Identities = 76/285 (26%), Positives = 138/285 (48%) Frame = +1 Query: 865 WEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFATEAETTALRTSFKQE 1044 WE+ ++ + G G V+ G + ++VA+K +R + + Sbjct: 161 WEVPFEEISELQWLGSGAQGAVFLGKFRAEEVAIK----------------KVREQNETD 204 Query: 1045 VAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYLI 1224 + KL HPN+ F G A C+++EY A G L Y + Sbjct: 205 IKHLRKLKHPNIIAFKGVCT------------------QAPCYCIIMEYCAHGQL--YEV 244 Query: 1225 KNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGVARVE 1404 RK+ +++V + ++ G++YLH KI+HRD+K+ N+L+ +KI+DFG ++ Sbjct: 245 LRAGRKITPRLLVDWSTGIASGMNYLHLHKIIHRDLKSPNVLVTHTDAVKISDFGTSKEL 304 Query: 1405 AQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDMPYPDLSFADVSS 1584 + M+ A GT+ ++APEV+ +P + K D++SFG+ LWE+ ++PY D+ + + Sbjct: 305 SDKSTKMSFA-GTVAWLAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSAIIW 363 Query: 1585 AVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 1719 V +L +P CP F +M++ W P RP + + ++ Sbjct: 364 GVGSNSLHLPVPSTCPDGFKILMKQTWQSKPRNRPSFRQTLMHLD 408
>P03949:ABL1_CAEEL Tyrosine-protein kinase abl-1 - Caenorhabditis elegans| Length = 1224 Score = 136 bits (343), Expect = 3e-31 Identities = 96/345 (27%), Positives = 157/345 (45%), Gaps = 4/345 (1%) Frame = +1 Query: 712 EVKFKRTGSLGSSDYVRADKIDLTSLDIQLEQQLNKKWSKSNIKSLGPKA--DWEIDLAK 885 EVKF+ G L V AD L L +KK + SL P A +WE+D ++ Sbjct: 256 EVKFRTLGELVHHHSVHAD-----GLICLLMYPASKKDKGRGLFSLSPNAPDEWELDRSE 310 Query: 886 LEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFATEAETTALRTSFKQEVAVWHKL 1065 + + + + G YG VY G + + + ED F E A+ L Sbjct: 311 IIMHNKLGGGQYGDVYEGYWKRHDCTIAVKALKEDAMPLH--------EFLAEAAIMKDL 362 Query: 1066 SHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYLIKNRRRKL 1245 H N+ + +G I + E++ G L +YL + + L Sbjct: 363 HHKNLVRLLGVCTHEAPFYI------------------ITEFMCNGNLLEYLRRTDKSLL 404 Query: 1246 AYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGVARVEAQNPKDM 1425 ++VQ+A ++ G+SYL +R +HRD+ N L+ +KIADFG+AR ++ Sbjct: 405 PPIILVQMASQIASGMSYLEARHFIHRDLAARNCLVSEHNIVKIADFGLARFMKEDTYTA 464 Query: 1426 -TGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDM-PYPDLSFADVSSAVVHQ 1599 GA + + APE L ++ K DV++FG+ LWE+ M PYP + ++V ++ Sbjct: 465 HAGAKFPIKWTAPEGLAFNTFSSKSDVWAFGVLLWEIATYGMAPYPGVELSNV-YGLLEN 523 Query: 1600 NLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDTS 1734 R D P+ CP + +M +CW+ +P RP ++ +E L +S Sbjct: 524 GFRMDGPQGCPPSVYRLMLQCWNWSPSDRPRFRDIHFNLENLISS 568
>P00521:ABL_MLVAB Tyrosine-protein kinase transforming protein Abl - Abelson murine| leukemia virus Length = 746 Score = 135 bits (340), Expect = 7e-31 Identities = 83/305 (27%), Positives = 141/305 (46%), Gaps = 3/305 (0%) Frame = +1 Query: 820 KWSKSNIKSLGPKAD-WEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGF 996 K +K I + P D WE++ + ++H + G YG VY G + + V + ED Sbjct: 105 KRNKPTIYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTM 164 Query: 997 ATEAETTALRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACC 1176 E F +E AV ++ HPN+ + +G I Sbjct: 165 EVE--------EFLKEAAVMKEIKHPNLVQLLGVCTREPPFYI----------------- 199 Query: 1177 VVVEYLAGGTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLD 1356 + E++ G L YL + R++++ V++ +A +S + YL + +HRD+ N L+ Sbjct: 200 -ITEFMTYGNLLDYLRECNRQEVSAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVG 258 Query: 1357 TQRNLKIADFGVARVEAQNPKDM-TGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEV 1533 +K+ADFG++R+ + GA + + APE L ++ K DV++FG+ LWE+ Sbjct: 259 ENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEI 318 Query: 1534 YCCDM-PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQ 1710 M PYP + + V ++ ++ R + P CP +MR CW NP RP E+ Q Sbjct: 319 ATYGMSPYPGIDLSQVYE-LLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQ 377 Query: 1711 LMEAL 1725 E + Sbjct: 378 AFETM 382
>P00520:ABL1_MOUSE Proto-oncogene tyrosine-protein kinase ABL1 - Mus musculus (Mouse)| Length = 1123 Score = 135 bits (340), Expect = 7e-31 Identities = 83/305 (27%), Positives = 141/305 (46%), Gaps = 3/305 (0%) Frame = +1 Query: 820 KWSKSNIKSLGPKAD-WEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGF 996 K +K I + P D WE++ + ++H + G YG VY G + + V + ED Sbjct: 219 KRNKPTIYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTM 278 Query: 997 ATEAETTALRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACC 1176 E F +E AV ++ HPN+ + +G I Sbjct: 279 EVE--------EFLKEAAVMKEIKHPNLVQLLGVCTREPPFYI----------------- 313 Query: 1177 VVVEYLAGGTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLD 1356 + E++ G L YL + R++++ V++ +A +S + YL + +HRD+ N L+ Sbjct: 314 -ITEFMTYGNLLDYLRECNRQEVSAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVG 372 Query: 1357 TQRNLKIADFGVARVEAQNPKDM-TGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEV 1533 +K+ADFG++R+ + GA + + APE L ++ K DV++FG+ LWE+ Sbjct: 373 ENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEI 432 Query: 1534 YCCDM-PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQ 1710 M PYP + + V ++ ++ R + P CP +MR CW NP RP E+ Q Sbjct: 433 ATYGMSPYPGIDLSQVYE-LLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQ 491 Query: 1711 LMEAL 1725 E + Sbjct: 492 AFETM 496
>P42687:SPK1_DUGTI Tyrosine-protein kinase SPK-1 - Dugesia tigrina (Planarian)| Length = 497 Score = 134 bits (337), Expect = 2e-30 Identities = 87/297 (29%), Positives = 140/297 (47%), Gaps = 9/297 (3%) Frame = +1 Query: 862 DWEIDLAKLEIRHVIAQGTYGTVYRGTYD-GQQVAVKLLDWGEDGFATEAETTALRTSFK 1038 D EI+ +EI + I +G +G+V+R + +VA K+L + A R F Sbjct: 212 DIEINRENIEILNEIGRGFFGSVHRAKWGRSYEVAAKMLQ----------SSKAEREKFV 261 Query: 1039 QEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQY 1218 E + HKL H + + +G D+ + ++VEY+ G+LK+Y Sbjct: 262 LEAKIMHKLRHRKIVELLGVCTEPQDMPM----------------LIIVEYMKNGSLKEY 305 Query: 1219 LIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGVAR 1398 L +K +V + ++S G++YL S K+VHRD++ +N+L+ K+ADFG+ Sbjct: 306 LKTPDGKKTNLNQMVHMMAEISEGMAYLESEKVVHRDLRADNILVANDLTRKVADFGLTE 365 Query: 1399 VEAQNPKDMTGATGTLGY--MAPEVLDGKPYNRKCDVYSFGICLWEVYC-CDMPYPDLSF 1569 + + D T Y APE K + K DV+S+GI ++E+ PYPD+ Sbjct: 366 LTDGSLGDQEKKTLRFPYKWTAPEAAKSKVFTSKSDVWSYGIVMFEILTWASSPYPDIPA 425 Query: 1570 ADVSSAVVHQNLRPDIPR-----CCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 +V V P+ + CCP IM CWD NP+KRP + + M+ L Sbjct: 426 KEVIEKVSKGYRMPNPEKFITGVCCPDEIYKIMIWCWDANPEKRPTFLVLQEKMDLL 482
>P00519:ABL1_HUMAN Proto-oncogene tyrosine-protein kinase ABL1 - Homo sapiens (Human)| Length = 1130 Score = 134 bits (336), Expect = 2e-30 Identities = 82/305 (26%), Positives = 140/305 (45%), Gaps = 3/305 (0%) Frame = +1 Query: 820 KWSKSNIKSLGPKAD-WEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGF 996 K +K + + P D WE++ + ++H + G YG VY G + + V + ED Sbjct: 219 KRNKPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTM 278 Query: 997 ATEAETTALRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACC 1176 E F +E AV ++ HPN+ + +G I Sbjct: 279 EVE--------EFLKEAAVMKEIKHPNLVQLLGVCTREPPFYI----------------- 313 Query: 1177 VVVEYLAGGTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLD 1356 + E++ G L YL + R+++ V++ +A +S + YL + +HRD+ N L+ Sbjct: 314 -ITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVG 372 Query: 1357 TQRNLKIADFGVARVEAQNPKDM-TGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEV 1533 +K+ADFG++R+ + GA + + APE L ++ K DV++FG+ LWE+ Sbjct: 373 ENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEI 432 Query: 1534 YCCDM-PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQ 1710 M PYP + + V ++ ++ R + P CP +MR CW NP RP E+ Q Sbjct: 433 ATYGMSPYPGIDLSQVYE-LLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQ 491 Query: 1711 LMEAL 1725 E + Sbjct: 492 AFETM 496
>P28028:BRAF1_MOUSE B-Raf proto-oncogene serine/threonine-protein kinase - Mus musculus| (Mouse) Length = 804 Score = 132 bits (332), Expect = 6e-30 Identities = 95/314 (30%), Positives = 158/314 (50%), Gaps = 12/314 (3%) Frame = +1 Query: 829 KSNIKSLGPKA---DWEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFA 999 +S +K+LG + DWEI ++ + I G++GTVY+G + G VAVK+L+ Sbjct: 472 RSRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHGD-VAVKMLN------- 523 Query: 1000 TEAETTALRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCV 1179 A T +FK EV V K H N+ F+G S P A + Sbjct: 524 VTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYS-----------------TKPQLA--I 564 Query: 1180 VVEYLAGGTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDT 1359 V ++ G +L +L K ++ +A ++G+ YLH++ I+HRD+K+ N+ L Sbjct: 565 VTQWCEGSSLYHHL-HIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHE 623 Query: 1360 QRNLKIADFGVARVEAQ--NPKDMTGATGTLGYMAPEVL---DGKPYNRKCDVYSFGICL 1524 +KI DFG+A V+++ +G++ +MAPEV+ D PY+ + DVY+FGI L Sbjct: 624 DLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVL 683 Query: 1525 WEVYCCDMPYPDLSFADVSSAVVHQN-LRPDIPRC---CPSAFANIMRKCWDGNPDKRPD 1692 +E+ +PY +++ D +V + L PD+ + CP A +M +C D+RP Sbjct: 684 YELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPL 743 Query: 1693 MDEVVQLMEALDTS 1734 +++ +E L S Sbjct: 744 FPQILASIELLARS 757
>P41240:CSK_HUMAN Tyrosine-protein kinase CSK - Homo sapiens (Human)| Length = 450 Score = 132 bits (331), Expect = 8e-30 Identities = 87/295 (29%), Positives = 143/295 (48%), Gaps = 3/295 (1%) Frame = +1 Query: 856 KADWEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFATEAETTALRTSF 1035 ++ W +++ +L++ I +G +G V G Y G +VAVK + + A +F Sbjct: 185 RSGWALNMKELKLLQTIGKGEFGDVMLGDYRGNKVAVKCI-----------KNDATAQAF 233 Query: 1036 KQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQ 1215 E +V +L H N+ + +G + V + G +V EY+A G+L Sbjct: 234 LAEASVMTQLRHSNLVQLLG---------VIVEEKGG--------LYIVTEYMAKGSLVD 276 Query: 1216 YLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGVA 1395 YL R L +++ +LD+ + YL VHRD+ N+L+ K++DFG+ Sbjct: 277 YLRSRGRSVLGGDCLLKFSLDVCEAMEYLEGNNFVHRDLAARNVLVSEDNVAKVSDFGLT 336 Query: 1396 RVEAQNPKDMTGATGTL--GYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCD-MPYPDLS 1566 + EA + +D TG L + APE L K ++ K DV+SFGI LWE+Y +PYP + Sbjct: 337 K-EASSTQD----TGKLPVKWTAPEALREKKFSTKSDVWSFGILLWEIYSFGRVPYPRIP 391 Query: 1567 FADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDT 1731 DV V + + D P CP A +M+ CW + RP ++ + +E + T Sbjct: 392 LKDVVPR-VEKGYKMDAPDGCPPAVYEVMKNCWHLDAAMRPSFLQLREQLEHIKT 445
>P41239:CSK_CHICK Tyrosine-protein kinase CSK - Gallus gallus (Chicken)| Length = 450 Score = 132 bits (331), Expect = 8e-30 Identities = 84/286 (29%), Positives = 138/286 (48%), Gaps = 3/286 (1%) Frame = +1 Query: 856 KADWEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFATEAETTALRTSF 1035 ++ W +++ L++ +I +G +G V G Y G +VAVK + + A +F Sbjct: 185 RSGWALNMKDLKLLQIIGKGEFGDVMLGDYRGNKVAVKCI-----------KNDATAQAF 233 Query: 1036 KQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQ 1215 E +V +L H N+ + +G + +V EY+A G+L Sbjct: 234 LAEASVMTQLRHSNLVQLLGVIVEEKS-----------------GLYIVTEYMAKGSLVD 276 Query: 1216 YLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGVA 1395 YL R L +++ +LD+ + YL + VHRD+ N+L+ K++DFG+ Sbjct: 277 YLRSRGRSVLGGDCLLKFSLDVCEAMEYLEANNFVHRDLAARNVLVSEDNIAKVSDFGLT 336 Query: 1396 RVEAQNPKDMTGATGTL--GYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCD-MPYPDLS 1566 + EA + +D TG L + APE L K ++ K DV+SFGI LWE+Y +PYP + Sbjct: 337 K-EASSTQD----TGKLPVKWTAPEALREKKFSTKSDVWSFGILLWEIYSFGRVPYPRIP 391 Query: 1567 FADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEV 1704 DV V + + D P CP+ +M+KCW +P RP ++ Sbjct: 392 LKDVVPR-VEKGYKMDPPDGCPAIVYEVMKKCWTLDPGHRPSFHQL 436
>P32577:CSK_RAT Tyrosine-protein kinase CSK - Rattus norvegicus (Rat)| Length = 450 Score = 131 bits (330), Expect = 1e-29 Identities = 87/295 (29%), Positives = 144/295 (48%), Gaps = 3/295 (1%) Frame = +1 Query: 856 KADWEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFATEAETTALRTSF 1035 ++ W +++ +L++ I +G +G V G Y G +VAVK + + A +F Sbjct: 185 RSGWALNMKELKLLQTIGKGEFGDVMLGDYRGNKVAVKCI-----------KNDATAQAF 233 Query: 1036 KQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQ 1215 E +V +L H N+ + +G + V + G +V EY+A G+L Sbjct: 234 LAEASVMTQLRHSNLVQLLG---------VIVEEKGG--------LYIVTEYMAKGSLVD 276 Query: 1216 YLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGVA 1395 YL R L +++ +LD+ + YL VHRD+ N+L+ K++DFG+ Sbjct: 277 YLRSRGRSVLGGDCLLKFSLDVCEAMEYLEGNNFVHRDLAARNVLVSEDNVAKVSDFGLT 336 Query: 1396 RVEAQNPKDMTGATGTL--GYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCD-MPYPDLS 1566 + EA + +D TG L + APE L K ++ K DV+SFGI LWE+Y +PYP + Sbjct: 337 K-EASSTQD----TGKLPVKWTAPEALREKKFSTKSDVWSFGILLWEIYSFGRVPYPRIP 391 Query: 1567 FADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDT 1731 DV V + + D P CP A ++M+ CW + RP ++ + +E + T Sbjct: 392 LKDVVPR-VEKGYKMDAPDGCPPAVYDVMKNCWHLDAATRPTFLQLREQLEHIRT 445
>P10533:RMIL_AVII1 Serine/threonine-protein kinase-transforming protein Rmil - Avian| retrovirus IC10 Length = 367 Score = 131 bits (329), Expect = 1e-29 Identities = 94/314 (29%), Positives = 158/314 (50%), Gaps = 12/314 (3%) Frame = +1 Query: 829 KSNIKSLGPKA---DWEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFA 999 ++ +K+LG + DWEI ++ + I G++GTVY+G + G VAVK+L+ Sbjct: 45 RNRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHGD-VAVKMLN------- 96 Query: 1000 TEAETTALRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCV 1179 A T +FK EV V K H N+ F+G S P A + Sbjct: 97 VTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYS-----------------TKPQLA--I 137 Query: 1180 VVEYLAGGTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDT 1359 V ++ G +L +L K ++ +A ++G+ YLH++ I+HRD+K+ N+ L Sbjct: 138 VTQWCEGSSLYHHL-HIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHE 196 Query: 1360 QRNLKIADFGVARVEAQ--NPKDMTGATGTLGYMAPEVL---DGKPYNRKCDVYSFGICL 1524 +KI DFG+A V+++ +G++ +MAPEV+ D PY+ + DVY+FGI L Sbjct: 197 DLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVL 256 Query: 1525 WEVYCCDMPYPDLSFADVSSAVVHQN-LRPDIPRC---CPSAFANIMRKCWDGNPDKRPD 1692 +E+ +PY +++ D +V + L PD+ + CP A +M +C D+RP Sbjct: 257 YELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPL 316 Query: 1693 MDEVVQLMEALDTS 1734 +++ +E L S Sbjct: 317 FPQILASIELLARS 330
>P27966:RMIL_AVEVR Serine/threonine-protein kinase-transforming protein Rmil - Avian| rous-associated virus type 1 Length = 450 Score = 131 bits (329), Expect = 1e-29 Identities = 94/314 (29%), Positives = 158/314 (50%), Gaps = 12/314 (3%) Frame = +1 Query: 829 KSNIKSLGPKA---DWEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFA 999 ++ +K+LG + DWEI ++ + I G++GTVY+G + G VAVK+L+ Sbjct: 61 RNRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHGD-VAVKMLN------- 112 Query: 1000 TEAETTALRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCV 1179 A T +FK EV V K H N+ F+G S P A + Sbjct: 113 VTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYS-----------------TKPQLA--I 153 Query: 1180 VVEYLAGGTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDT 1359 V ++ G +L +L K ++ +A ++G+ YLH++ I+HRD+K+ N+ L Sbjct: 154 VTQWCEGSSLYHHL-HIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHE 212 Query: 1360 QRNLKIADFGVARVEAQ--NPKDMTGATGTLGYMAPEVL---DGKPYNRKCDVYSFGICL 1524 +KI DFG+A V+++ +G++ +MAPEV+ D PY+ + DVY+FGI L Sbjct: 213 DLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVL 272 Query: 1525 WEVYCCDMPYPDLSFADVSSAVVHQN-LRPDIPRC---CPSAFANIMRKCWDGNPDKRPD 1692 +E+ +PY +++ D +V + L PD+ + CP A +M +C D+RP Sbjct: 273 YELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPL 332 Query: 1693 MDEVVQLMEALDTS 1734 +++ +E L S Sbjct: 333 FPQILASIELLARS 346
>Q9V3Q6:M3K7_DROME Mitogen-activated protein kinase kinase kinase 7 - Drosophila| melanogaster (Fruit fly) Length = 678 Score = 131 bits (329), Expect = 1e-29 Identities = 82/289 (28%), Positives = 135/289 (46%), Gaps = 4/289 (1%) Frame = +1 Query: 871 IDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFATEAETTALRTSFKQEVA 1050 +D +++ +R + G+YG V + + + VAVK E +A + ++EV Sbjct: 14 VDFSEITLREKVGHGSYGVVCKAVWRDKLVAVK-----------EFFASAEQKDIEKEVK 62 Query: 1051 VWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYLIKN 1230 ++ HPN+ G S +A +++E+ GG+L +L Sbjct: 63 QLSRVKHPNIIALHGISSYQ------------------QATYLIMEFAEGGSLHNFLHGK 104 Query: 1231 RRRKLAYKVVVQLALDLSRGLSYLHS---RKIVHRDVKTENMLLDTQ-RNLKIADFGVAR 1398 + + + A + GL+YLH+ + ++HRDVK N+LL + RNLKI DFG Sbjct: 105 VKPAYSLAHAMSWARQCAEGLAYLHAMTPKPLIHRDVKPLNLLLTNKGRNLKICDFGTV- 163 Query: 1399 VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDMPYPDLSFADV 1578 A MT G+ +MAPEV +G Y KCD++S+ I LWEV P+ + A Sbjct: 164 --ADKSTMMTNNRGSAAWMAPEVFEGSKYTEKCDIFSWAIVLWEVLSRKQPFKGIDNAYT 221 Query: 1579 SSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 +++ RP + CP ++M CW P+ RP M +V +M + Sbjct: 222 IQWKIYKGERPPLLTTCPKRIEDLMTACWKTVPEDRPSMQYIVGVMHEI 270
>P15056:BRAF1_HUMAN B-Raf proto-oncogene serine/threonine-protein kinase - Homo sapiens| (Human) Length = 766 Score = 131 bits (329), Expect = 1e-29 Identities = 94/314 (29%), Positives = 158/314 (50%), Gaps = 12/314 (3%) Frame = +1 Query: 829 KSNIKSLGPKA---DWEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFA 999 ++ +K+LG + DWEI ++ + I G++GTVY+G + G VAVK+L+ Sbjct: 435 RNRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHGD-VAVKMLN------- 486 Query: 1000 TEAETTALRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCV 1179 A T +FK EV V K H N+ F+G S P A + Sbjct: 487 VTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYS-----------------TKPQLA--I 527 Query: 1180 VVEYLAGGTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDT 1359 V ++ G +L +L K ++ +A ++G+ YLH++ I+HRD+K+ N+ L Sbjct: 528 VTQWCEGSSLYHHL-HIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHE 586 Query: 1360 QRNLKIADFGVARVEAQ--NPKDMTGATGTLGYMAPEVL---DGKPYNRKCDVYSFGICL 1524 +KI DFG+A V+++ +G++ +MAPEV+ D PY+ + DVY+FGI L Sbjct: 587 DLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVL 646 Query: 1525 WEVYCCDMPYPDLSFADVSSAVVHQN-LRPDIPRC---CPSAFANIMRKCWDGNPDKRPD 1692 +E+ +PY +++ D +V + L PD+ + CP A +M +C D+RP Sbjct: 647 YELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPL 706 Query: 1693 MDEVVQLMEALDTS 1734 +++ +E L S Sbjct: 707 FPQILASIELLARS 720
>P34908:BRAF1_COTJA B-Raf proto-oncogene serine/threonine-protein kinase - Coturnix| coturnix japonica (Japanese quail) Length = 807 Score = 131 bits (329), Expect = 1e-29 Identities = 94/314 (29%), Positives = 158/314 (50%), Gaps = 12/314 (3%) Frame = +1 Query: 829 KSNIKSLGPKA---DWEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFA 999 ++ +K+LG + DWEI ++ + I G++GTVY+G + G VAVK+L+ Sbjct: 475 RNRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHGD-VAVKMLN------- 526 Query: 1000 TEAETTALRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCV 1179 A T +FK EV V K H N+ F+G S P A + Sbjct: 527 VTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYS-----------------TKPQLA--I 567 Query: 1180 VVEYLAGGTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDT 1359 V ++ G +L +L K ++ +A ++G+ YLH++ I+HRD+K+ N+ L Sbjct: 568 VTQWCEGSSLYHHL-HIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHE 626 Query: 1360 QRNLKIADFGVARVEAQ--NPKDMTGATGTLGYMAPEVL---DGKPYNRKCDVYSFGICL 1524 +KI DFG+A V+++ +G++ +MAPEV+ D PY+ + DVY+FGI L Sbjct: 627 DLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVL 686 Query: 1525 WEVYCCDMPYPDLSFADVSSAVVHQN-LRPDIPRC---CPSAFANIMRKCWDGNPDKRPD 1692 +E+ +PY +++ D +V + L PD+ + CP A +M +C D+RP Sbjct: 687 YELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPL 746 Query: 1693 MDEVVQLMEALDTS 1734 +++ +E L S Sbjct: 747 FPQILASIELLARS 760
>Q04982:BRAF1_CHICK B-Raf proto-oncogene serine/threonine-protein kinase - Gallus gallus| (Chicken) Length = 806 Score = 131 bits (329), Expect = 1e-29 Identities = 94/314 (29%), Positives = 158/314 (50%), Gaps = 12/314 (3%) Frame = +1 Query: 829 KSNIKSLGPKA---DWEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFA 999 ++ +K+LG + DWEI ++ + I G++GTVY+G + G VAVK+L+ Sbjct: 475 RNRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHGD-VAVKMLN------- 526 Query: 1000 TEAETTALRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCV 1179 A T +FK EV V K H N+ F+G S P A + Sbjct: 527 VTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYS-----------------TKPQLA--I 567 Query: 1180 VVEYLAGGTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDT 1359 V ++ G +L +L K ++ +A ++G+ YLH++ I+HRD+K+ N+ L Sbjct: 568 VTQWCEGSSLYHHL-HIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHE 626 Query: 1360 QRNLKIADFGVARVEAQ--NPKDMTGATGTLGYMAPEVL---DGKPYNRKCDVYSFGICL 1524 +KI DFG+A V+++ +G++ +MAPEV+ D PY+ + DVY+FGI L Sbjct: 627 DLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVL 686 Query: 1525 WEVYCCDMPYPDLSFADVSSAVVHQN-LRPDIPRC---CPSAFANIMRKCWDGNPDKRPD 1692 +E+ +PY +++ D +V + L PD+ + CP A +M +C D+RP Sbjct: 687 YELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPL 746 Query: 1693 MDEVVQLMEALDTS 1734 +++ +E L S Sbjct: 747 FPQILASIELLARS 760
>P00522:ABL_DROME Tyrosine-protein kinase Abl - Drosophila melanogaster (Fruit fly)| Length = 1620 Score = 130 bits (327), Expect = 2e-29 Identities = 87/305 (28%), Positives = 143/305 (46%), Gaps = 5/305 (1%) Frame = +1 Query: 820 KWSKSNIKSLGPKAD-WEIDLAKLEIRHVIAQGTYGTVYRGTYD--GQQVAVKLLDWGED 990 K +K + L P+ D WEI + ++H + G YG VY + G VAVK L Sbjct: 348 KQNKPTVFPLSPEPDEWEICRTDIMMKHKLGGGQYGEVYEAVWKRYGNTVAVKTL----- 402 Query: 991 GFATEAETTALRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARA 1170 + +T AL+ F +E A+ ++ HPN+ + +G I Sbjct: 403 ----KEDTMALK-DFLEEAAIMKEMKHPNLVQLIGVCTREPPFYI--------------- 442 Query: 1171 CCVVVEYLAGGTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENML 1350 + E+++ G L +L R L ++ +A ++ G+SYL SR +HRD+ N L Sbjct: 443 ---ITEFMSHGNLLDFLRSAGRETLDAVALLYMATQIASGMSYLESRNYIHRDLAARNCL 499 Query: 1351 LDTQRNLKIADFGVARVEAQNPKDM-TGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLW 1527 + + +K+ADFG+AR+ + GA + + APE L ++ K DV++FG+ LW Sbjct: 500 VGDNKLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAYNKFSTKSDVWAFGVLLW 559 Query: 1528 EVYCCDM-PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEV 1704 E+ M PYP + DV + + R + P CP ++MR+CW + RP + Sbjct: 560 EIATYGMSPYPAIDLTDVYHK-LDKGYRMERPPGCPPEVYDLMRQCWQWDATDRPTFKSI 618 Query: 1705 VQLME 1719 +E Sbjct: 619 HHALE 623
>Q4JIM5:ABL2_MOUSE Tyrosine-protein kinase ABL2 - Mus musculus (Mouse)| Length = 1182 Score = 130 bits (327), Expect = 2e-29 Identities = 84/305 (27%), Positives = 141/305 (46%), Gaps = 3/305 (0%) Frame = +1 Query: 820 KWSKSNIKSLGPKAD-WEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGF 996 K +K + + P D WE++ + ++H + G YG VY G + + V + + ED Sbjct: 265 KCNKPTVYGVSPIHDKWEMERTDITMKHKLGGGQYGEVYVGVWKKYSLTVAVKTFKEDTM 324 Query: 997 ATEAETTALRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACC 1176 E F +E AV ++ HPN+ + +G L+ P Sbjct: 325 EVE--------EFLKEAAVMKEIKHPNLVQL----LGVCTLEPPFY-------------- 358 Query: 1177 VVVEYLAGGTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLD 1356 +V EY+ G L YL + R ++ V++ +A +S + YL + +HRD+ N L+ Sbjct: 359 IVTEYMPYGNLLDYLRECSREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVG 418 Query: 1357 TQRNLKIADFGVARVEAQNPKDM-TGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEV 1533 +K+ADFG++R+ + GA + + APE L ++ K DV++FG+ LWE+ Sbjct: 419 ENHVVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEI 478 Query: 1534 YCCDM-PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQ 1710 M PYP + + V ++ + R + P CP +MR CW +P RP E Q Sbjct: 479 ATYGMSPYPGIDLSQVYD-LLEKGYRMEQPEGCPPKVYELMRACWKWSPADRPSFAETHQ 537 Query: 1711 LMEAL 1725 E + Sbjct: 538 AFETM 542
>P10447:ABL_FSVHY Tyrosine-protein kinase transforming protein Abl - Feline sarcoma| virus (strain Hardy-Zuckerman 2) Length = 439 Score = 129 bits (325), Expect = 4e-29 Identities = 83/305 (27%), Positives = 139/305 (45%), Gaps = 10/305 (3%) Frame = +1 Query: 820 KWSKSNIKSLGPKAD-WEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGF 996 K +K + + P D WE++ + ++H + G YG VY G + + V + ED Sbjct: 168 KRNKPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTM 227 Query: 997 ATEAETTALRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACC 1176 E F +E AV ++ HPN+ + +G I Sbjct: 228 EVE--------EFLKEAAVMKEIKHPNLVQLLGVCTREPPFYI----------------- 262 Query: 1177 VVVEYLAGGTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLD 1356 + E++ G L YL + R+++ V++ +A +S + YL + +HRD+ N L+ Sbjct: 263 -ITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVG 321 Query: 1357 TQRNLKIADFGVARVEAQNPKDMTGATGT--------LGYMAPEVLDGKPYNRKCDVYSF 1512 +K+ADFG++R+ MTG T T + + APE L ++ K DV++F Sbjct: 322 ENHLVKVADFGLSRL-------MTGDTYTAHAGTKFPIKWTAPESLAYNKFSIKSDVWAF 374 Query: 1513 GICLWEVYCCDM-PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRP 1689 G+ LWE+ M PYP + + V ++ ++ R + P CP +MR CW NP RP Sbjct: 375 GVLLWEIATYGMSPYPGIDLSQVYE-LLEKDYRMERPEGCPEKVYELMRACWQWNPSDRP 433 Query: 1690 DMDEV 1704 E+ Sbjct: 434 AFAEI 438
>P42684:ABL2_HUMAN Tyrosine-protein kinase ABL2 - Homo sapiens (Human)| Length = 1182 Score = 129 bits (325), Expect = 4e-29 Identities = 84/305 (27%), Positives = 140/305 (45%), Gaps = 3/305 (0%) Frame = +1 Query: 820 KWSKSNIKSLGPKAD-WEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGF 996 K +K + + P D WE++ + ++H + G YG VY G + + V + ED Sbjct: 265 KCNKPTVYGVSPIHDKWEMERTDITMKHKLGGGQYGEVYVGVWKKYSLTVAVKTLKEDTM 324 Query: 997 ATEAETTALRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACC 1176 E F +E AV ++ HPN+ + +G L+ P Sbjct: 325 EVE--------EFLKEAAVMKEIKHPNLVQL----LGVCTLEPPFY-------------- 358 Query: 1177 VVVEYLAGGTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLD 1356 +V EY+ G L YL + R ++ V++ +A +S + YL + +HRD+ N L+ Sbjct: 359 IVTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVG 418 Query: 1357 TQRNLKIADFGVARVEAQNPKDM-TGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEV 1533 +K+ADFG++R+ + GA + + APE L ++ K DV++FG+ LWE+ Sbjct: 419 ENHVVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEI 478 Query: 1534 YCCDM-PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQ 1710 M PYP + + V ++ + R + P CP +MR CW +P RP E Q Sbjct: 479 ATYGMSPYPGIDLSQVYD-LLEKGYRMEQPEGCPPKVYELMRACWKWSPADRPSFAETHQ 537 Query: 1711 LMEAL 1725 E + Sbjct: 538 AFETM 542
>P09760:FER_RAT Proto-oncogene tyrosine-protein kinase FER - Rattus norvegicus (Rat)| Length = 323 Score = 129 bits (324), Expect = 5e-29 Identities = 86/311 (27%), Positives = 143/311 (45%), Gaps = 3/311 (0%) Frame = +1 Query: 802 EQQLNKKWSKSNIKSLGPKADWEIDLAKLEIRHVIAQGTYGTVYRGTY-DGQQVAVKLLD 978 +Q + KK + + W ++ + + ++ +G +G VY+GT D VAVK Sbjct: 36 KQVITKKSGVVLLNPIPKDKKWVLNHEDVSLGELLGKGNFGEVYKGTLKDKTPVAVKT-- 93 Query: 979 WGEDGFATEAETTALRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANL 1158 E L+ F QE + + HPN+ K +G + I Sbjct: 94 ------CKEDLPQELKIKFLQEAKILKQYDHPNIVKLIGVCTQRQPVYI----------- 136 Query: 1159 PARACCVVVEYLAGGTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKT 1338 ++E + GG +L K R+ +L K +V+ +LD++ G+ YL + +HRD+ Sbjct: 137 -------IMELVPGGDFLSFLRK-RKDELKLKQLVRFSLDVAAGMLYLEGKNCIHRDLAA 188 Query: 1339 ENMLLDTQRNLKIADFGVARVEAQNPKDMTGATG-TLGYMAPEVLDGKPYNRKCDVYSFG 1515 N L+ LKI+DFG++R E +G + + APE L+ Y+ + DV+SFG Sbjct: 189 RNCLVGENNTLKISDFGMSRQEDGGVYSSSGLKQIPIKWTAPEALNYGRYSSESDVWSFG 248 Query: 1516 ICLWEVYCCDM-PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPD 1692 I LWE + + PYP ++ V + R P+ CP IM KCWD P+ RP Sbjct: 249 ILLWETFSLGVCPYPGMTNQQAREQ-VERGYRMSAPQNCPEEIFTIMMKCWDYKPENRPK 307 Query: 1693 MDEVVQLMEAL 1725 ++ + + A+ Sbjct: 308 FSDLHKELTAI 318
>P70451:FER_MOUSE Proto-oncogene tyrosine-protein kinase FER - Mus musculus (Mouse)| Length = 823 Score = 129 bits (324), Expect = 5e-29 Identities = 85/304 (27%), Positives = 141/304 (46%), Gaps = 3/304 (0%) Frame = +1 Query: 802 EQQLNKKWSKSNIKSLGPKADWEIDLAKLEIRHVIAQGTYGTVYRGTY-DGQQVAVKLLD 978 +Q + KK + + W ++ + + ++ +G +G VY+GT D VA+K Sbjct: 536 KQVITKKSGVVLLNPIPKDKKWVLNHEDVSLGELLGKGNFGEVYKGTLKDKTPVAIKT-- 593 Query: 979 WGEDGFATEAETTALRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANL 1158 E L+ F QE + + HPN+ K +G + I Sbjct: 594 ------CKEDLPQELKIKFLQEAKILKQYDHPNIVKLIGVCTQRQPVYI----------- 636 Query: 1159 PARACCVVVEYLAGGTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKT 1338 ++E + GG +L K R+ +L K +V+ +LD++ G+ YL S+ +HRD+ Sbjct: 637 -------IMELVPGGDFLTFLRK-RKDELKLKQLVRFSLDVAAGMLYLESKNCIHRDLAA 688 Query: 1339 ENMLLDTQRNLKIADFGVARVEAQNPKDMTGATG-TLGYMAPEVLDGKPYNRKCDVYSFG 1515 N L+ LKI+DFG++R E +G + + APE L+ Y+ + DV+SFG Sbjct: 689 RNCLVGENNTLKISDFGMSRQEDGGVYSSSGLKQIPIKWTAPEALNYGRYSSESDVWSFG 748 Query: 1516 ICLWEVYCCDM-PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPD 1692 I LWE + + PYP ++ V + R P+ CP IM KCWD P+ RP Sbjct: 749 ILLWETFSLGVCPYPGMTNQQAREQ-VERGYRMSAPQNCPEEVFTIMMKCWDYKPENRPK 807 Query: 1693 MDEV 1704 +++ Sbjct: 808 FNDL 811
>Q0VBZ0:CSK_BOVIN Tyrosine-protein kinase CSK - Bos taurus (Bovine)| Length = 450 Score = 129 bits (324), Expect = 5e-29 Identities = 85/295 (28%), Positives = 139/295 (47%), Gaps = 3/295 (1%) Frame = +1 Query: 856 KADWEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFATEAETTALRTSF 1035 ++ W +++ L++ I +G +G V G Y G +VAVK + + A +F Sbjct: 185 RSGWALNMKDLKLLQTIGKGEFGDVMLGDYRGNKVAVKCI-----------KNDATAQAF 233 Query: 1036 KQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQ 1215 E +V +L H N+ + +G + +V EY+A G+L Sbjct: 234 LAEASVMTQLRHSNLVQLLGVIVEEKS-----------------GLYIVTEYMAKGSLVD 276 Query: 1216 YLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGVA 1395 YL R L +++ +LD+ + YL VHRD+ N+L+ K++DFG+ Sbjct: 277 YLRSRGRSVLGGDCLLKFSLDVCEAMEYLEGNNFVHRDLAARNVLVSEDNVAKVSDFGLT 336 Query: 1396 RVEAQNPKDMTGATGTL--GYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCD-MPYPDLS 1566 + EA + +D TG L + APE L K ++ K DV+SFGI LWE+Y +PYP + Sbjct: 337 K-EASSTQD----TGKLPVKWTAPEALREKKFSTKSDVWSFGILLWEIYSFGRVPYPRIP 391 Query: 1567 FADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDT 1731 DV V + + D P CP A +M+ CW + RP ++ + +E + T Sbjct: 392 LKDVVPR-VEKGYKMDAPDGCPPAVYEVMKNCWHLDAATRPSFLQLREQLERIKT 445
>P42689:SRK3_SPOLA Tyrosine-protein kinase SRK3 - Spongilla lacustris (Freshwater| sponge) Length = 334 Score = 127 bits (320), Expect = 1e-28 Identities = 91/324 (28%), Positives = 152/324 (46%), Gaps = 8/324 (2%) Frame = +1 Query: 799 LEQQLNKKWSKSNI---KSLGPKADWEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQ-VAV 966 L Q+L++ S++NI L K +WEID ++++ + QG +G V+ G ++G VAV Sbjct: 34 LAQRLSRPCSRANIPITSGLSYKDEWEIDRTTIQLQRKLGQGNFGEVWAGVWNGTTAVAV 93 Query: 967 KLLDWGEDGFATEAETTALRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGA 1146 K L + +T ++ F QE V K+ HPN+ + + P+ Sbjct: 94 KTL---------KPDTMEVK-DFVQEAQVMKKIHHPNLLQLYAVCT----IGEPIY---- 135 Query: 1147 RANLPARACCVVVEYLAGGTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHR 1326 +V E + G++ +YL + + +V ++ ++ G++YL + +HR Sbjct: 136 ----------IVTELMKYGSMLEYLKHGEGKNITLHQMVDMSAQIASGMTYLEAHSYIHR 185 Query: 1327 DVKTENMLLDTQRNLKIADFGVARV---EAQNPKDMTGATGTLGYMAPEVLDGKPYNRKC 1497 D+ N+L+ K+ADFG+ARV + NP++ G + + APE + K Sbjct: 186 DLAARNILVGEGNVCKVADFGLARVIKEDIYNPRE--GTKFPIKWTAPEAALYNRFTIKS 243 Query: 1498 DVYSFGICLWEVYCCD-MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGN 1674 DV+SFG+ + E+ MPYP ++ V A V + R P CP IM CW Sbjct: 244 DVWSFGVLISEIVTHGRMPYPGMTNRQVLEA-VDRGYRMPCPEGCPDPLYKIMLSCWKHE 302 Query: 1675 PDKRPDMDEVVQLMEALDTSKGGG 1746 PD RP + + L+E S G Sbjct: 303 PDDRPTFESLKNLLEDYYVSAAEG 326
>P16591:FER_HUMAN Proto-oncogene tyrosine-protein kinase FER - Homo sapiens (Human)| Length = 822 Score = 127 bits (320), Expect = 1e-28 Identities = 85/304 (27%), Positives = 140/304 (46%), Gaps = 3/304 (0%) Frame = +1 Query: 802 EQQLNKKWSKSNIKSLGPKADWEIDLAKLEIRHVIAQGTYGTVYRGTY-DGQQVAVKLLD 978 +Q + KK + + W + + + ++ +G +G VY+GT D VAVK Sbjct: 535 KQVITKKSGVVLLNPIPKDKKWILSHEDVILGELLGKGNFGEVYKGTLKDKTSVAVKT-- 592 Query: 979 WGEDGFATEAETTALRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANL 1158 E L+ F QE + + HPN+ K +G + I Sbjct: 593 ------CKEDLPQELKIKFLQEAKILKQYDHPNIVKLIGVCTQRQPVYI----------- 635 Query: 1159 PARACCVVVEYLAGGTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKT 1338 ++E ++GG +L + ++ +L K +V+ +LD + G+ YL S+ +HRD+ Sbjct: 636 -------IMELVSGGDFLTFL-RRKKDELKLKQLVKFSLDAAAGMLYLESKNCIHRDLAA 687 Query: 1339 ENMLLDTQRNLKIADFGVARVEAQNPKDMTGATG-TLGYMAPEVLDGKPYNRKCDVYSFG 1515 N L+ LKI+DFG++R E +G + + APE L+ Y+ + DV+SFG Sbjct: 688 RNCLVGENNVLKISDFGMSRQEDGGVYSSSGLKQIPIKWTAPEALNYGRYSSESDVWSFG 747 Query: 1516 ICLWEVYCCDM-PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPD 1692 I LWE + + PYP ++ V + R P+ CP + IM KCWD P+ RP Sbjct: 748 ILLWETFSLGVCPYPGMTNQQAREQ-VERGYRMSAPQHCPEDISKIMMKCWDYKPENRPK 806 Query: 1693 MDEV 1704 E+ Sbjct: 807 FSEL 810
>Q9TTY2:FER_CANFA Proto-oncogene tyrosine-protein kinase FER - Canis familiaris (Dog)| Length = 823 Score = 127 bits (319), Expect = 2e-28 Identities = 85/304 (27%), Positives = 140/304 (46%), Gaps = 3/304 (0%) Frame = +1 Query: 802 EQQLNKKWSKSNIKSLGPKADWEIDLAKLEIRHVIAQGTYGTVYRGTY-DGQQVAVKLLD 978 +Q + KK + + W ++ + + ++ +G +G VY+G D VAVK Sbjct: 535 KQVITKKSGVVLLNPIPKDKKWVLNHEDVTLGELLGKGNFGEVYKGILKDKTAVAVKT-- 592 Query: 979 WGEDGFATEAETTALRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANL 1158 E L+ F QE + + HPN+ K +G + I Sbjct: 593 ------CKEDLPQELKIKFLQEAKILKQYDHPNIVKLIGVCTQRQPIYI----------- 635 Query: 1159 PARACCVVVEYLAGGTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKT 1338 ++E + GG +L K ++ ++ K +V+ +LD + G+SYL S+ +HRD+ Sbjct: 636 -------IMELVPGGDFLSFLRK-KKDEIKLKQLVKFSLDAASGMSYLESKNCIHRDLAA 687 Query: 1339 ENMLLDTQRNLKIADFGVARVEAQNPKDMTGATG-TLGYMAPEVLDGKPYNRKCDVYSFG 1515 N L+ LKI+DFG++R E +G + + APE L+ Y+ + DV+SFG Sbjct: 688 RNCLVGENNVLKISDFGMSRQEDGGVYSSSGLKQIPIKWTAPEALNYGRYSSESDVWSFG 747 Query: 1516 ICLWEVYCCDM-PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPD 1692 I LWE + + PYP ++ + V + R P+ CP IM KCWD P+ RP Sbjct: 748 ILLWETFSLGVCPYPGMTNQQATEQ-VERGYRISAPQHCPEDIFKIMMKCWDYKPENRPK 806 Query: 1693 MDEV 1704 E+ Sbjct: 807 FSEL 810
>Q07292:KRAF1_CAEEL Raf homolog serine/threonine-protein kinase - Caenorhabditis elegans| Length = 813 Score = 127 bits (318), Expect = 2e-28 Identities = 89/296 (30%), Positives = 151/296 (51%), Gaps = 13/296 (4%) Frame = +1 Query: 862 DWEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFATEAETTALRTSFKQ 1041 DWEI + I++ + G++GTVYRG + G VA+K L+ + T + +FK Sbjct: 473 DWEILPNEFIIQYKVGSGSFGTVYRGEFFGT-VAIKKLNVVDP-------TPSQMAAFKN 524 Query: 1042 EVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYL 1221 EVAV K H NV F+G + ++ ++ G +L +++ Sbjct: 525 EVAVLKKTRHLNVLLFMGW-------------------VREPEIAIITQWCEGSSLYRHI 565 Query: 1222 -IKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENM-LLDTQRNLKIADFGVA 1395 ++ R + ++ + +S G++YLHS+ I+HRD+KT N+ L+D +KI DFG+A Sbjct: 566 HVQEPRVEFEMGAIIDILKQVSLGMNYLHSKNIIHRDLKTNNIFLMDDMSTVKIGDFGLA 625 Query: 1396 RVEAQ----NPKDMTGATGTLGYMAPEVL---DGKPYNRKCDVYSFGICLWEVYCCDMPY 1554 V+ + + TG++ +MAPEV+ D PY + DVYSFGIC++E+ +PY Sbjct: 626 TVKTKWTVNGGQQQQQPTGSILWMAPEVIRMQDDNPYTPQSDVYSFGICMYEILSSHLPY 685 Query: 1555 PDLSFADVSSAVVHQN-LRPD---IPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQ 1710 +++ D +V + LRPD I P + + C + ++RP EV++ Sbjct: 686 SNINNRDQILFMVGRGYLRPDRSKIRHDTPKSMLKLYDNCIMFDRNERPVFGEVLE 741
>Q61UC4:KRAF1_CAEBR Raf homolog serine/threonine-protein kinase - Caenorhabditis briggsae| Length = 811 Score = 126 bits (316), Expect = 4e-28 Identities = 88/296 (29%), Positives = 150/296 (50%), Gaps = 13/296 (4%) Frame = +1 Query: 862 DWEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFATEAETTALRTSFKQ 1041 DWEI + I + + G++GTVYRG + G VA+K L+ + T + +FK Sbjct: 471 DWEILPNEFVIHYKVGSGSFGTVYRGEFFGT-VAIKKLNVVDP-------TPSQMAAFKN 522 Query: 1042 EVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYL 1221 EVAV K H NV F+G + ++ ++ G +L +++ Sbjct: 523 EVAVLKKTRHLNVLLFMGW-------------------VREPEIAIITQWCEGSSLYRHI 563 Query: 1222 -IKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENM-LLDTQRNLKIADFGVA 1395 ++ R + V+ + +S G++YLHS+ I+HRD+KT N+ L+D +KI DFG+A Sbjct: 564 HVQEPRVEFEMSAVIDILKQVSLGMNYLHSKNIIHRDLKTNNIFLMDDMSTVKIGDFGLA 623 Query: 1396 RVEAQ----NPKDMTGATGTLGYMAPEVL---DGKPYNRKCDVYSFGICLWEVYCCDMPY 1554 V+ + + TG++ +MAPEV+ D PY + DVYSFG+C++E+ +PY Sbjct: 624 TVKTKWTVNGGQQQQQPTGSILWMAPEVIRMQDDNPYTPQSDVYSFGVCMYEILSSHLPY 683 Query: 1555 PDLSFADVSSAVVHQN-LRPD---IPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQ 1710 +++ D +V + L+PD I P + + C + ++RP EV++ Sbjct: 684 SNINNRDQILFMVGRGYLKPDRSKIRTDTPKSLMKLYDNCIMFDRNERPVFGEVLE 739
>P41241:CSK_MOUSE Tyrosine-protein kinase CSK - Mus musculus (Mouse)| Length = 450 Score = 126 bits (316), Expect = 4e-28 Identities = 86/295 (29%), Positives = 143/295 (48%), Gaps = 3/295 (1%) Frame = +1 Query: 856 KADWEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFATEAETTALRTSF 1035 ++ W +++ +L++ I +G +G V G Y G +VAVK + + A +F Sbjct: 185 RSGWALNMKELKLLQTIGKGEFGDVMLGDYRGNKVAVKCI-----------KNDATAQAF 233 Query: 1036 KQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQ 1215 E +V +L H N+ + +G + V + G +V EY+A G+L Sbjct: 234 LAEASVMTQLRHSNLVQLLG---------VIVEEKGG--------LYIVTEYMAKGSLVD 276 Query: 1216 YLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGVA 1395 YL R L +++ +LD+ + YL VHRD+ N+L+ K++DFG+ Sbjct: 277 YLRSRGRSVLGGDCLLKFSLDVLEAMEYLEGNNFVHRDLAARNVLVSEDNVAKVSDFGLT 336 Query: 1396 RVEAQNPKDMTGATGTL--GYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCD-MPYPDLS 1566 + EA + +D TG L + APE L K ++ K DV+SFGI LWE+Y +PYP + Sbjct: 337 K-EASSTQD----TGKLPVKWTAPEALREKKFSTKSDVWSFGILLWEIYSFGRVPYPRIP 391 Query: 1567 FADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDT 1731 DV V + + D P CP A ++M+ C + RP ++ + +E + T Sbjct: 392 LKDVVPR-VEKGYKMDAPDGCPPAVYDVMKNCSHLDAATRPTFLQLREQLEHIKT 445
>P16056:MET_MOUSE Hepatocyte growth factor receptor precursor - Mus musculus (Mouse)| Length = 1379 Score = 125 bits (315), Expect = 6e-28 Identities = 101/360 (28%), Positives = 165/360 (45%), Gaps = 21/360 (5%) Frame = +1 Query: 709 PEVKFKRTGSLGSSDYVRADKIDL----TSLDIQLEQQLNKKWSKSNIKSLGPKADWEID 876 PE +F + G+ V+ DL TS D + L + ++ +L P+ + Sbjct: 1006 PEDQFPNSSQNGACRQVQYPLTDLSPILTSGDSDISSPLLQNTVHIDLSALNPELVQAVQ 1065 Query: 877 LAKL-------EIRHVIAQGTYGTVYRGTY---DGQQV--AVKLLDWGEDGFATEAETTA 1020 + VI +G +G VY GT DG+++ AVK L+ T+ E + Sbjct: 1066 HVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNR-----ITDIEEVS 1120 Query: 1021 LRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAG 1200 F E + SHPNV +G + + + VV+ Y+ Sbjct: 1121 ---QFLTEGIIMKDFSHPNVLSLLGICLRSEGSPL-----------------VVLPYMKH 1160 Query: 1201 GTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIA 1380 G L+ + I+N K ++ L +++G+ YL S+K VHRD+ N +LD + +K+A Sbjct: 1161 GDLRNF-IRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVA 1219 Query: 1381 DFGVAR----VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDM 1548 DFG+AR E + + TGA + +MA E L + + K DV+SFG+ LWE+ Sbjct: 1220 DFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGA 1279 Query: 1549 -PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 PYPD++ D++ ++ Q R P CP A +M KCW + RP E+V + ++ Sbjct: 1280 PPYPDVNTFDITIYLL-QGRRLLQPEYCPDALYEVMLKCWHPKAEMRPSFSELVSRISSI 1338
>Q09YH7:MET_SAIBB Hepatocyte growth factor receptor precursor - Saimiri boliviensis| boliviensis (Bolivian squirrel monkey) Length = 1381 Score = 124 bits (312), Expect = 1e-27 Identities = 101/360 (28%), Positives = 162/360 (45%), Gaps = 21/360 (5%) Frame = +1 Query: 709 PEVKFKRTGSLGSSDYVRADKID----LTSLDIQLEQQLNKKWSKSNIKSLGPKADWEID 876 PE +F + GS V+ D LTS D + L + ++ +L P+ + Sbjct: 1008 PEDQFPNSSQNGSCRQVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNPELVQAVQ 1067 Query: 877 LAKL-------EIRHVIAQGTYGTVYRGTY---DGQQV--AVKLLDWGEDGFATEAETTA 1020 + VI +G +G VY GT DG+++ AVK L+ D Sbjct: 1068 HVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITD--------IG 1119 Query: 1021 LRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAG 1200 + F E + SHPNV +G + + + VV+ Y+ Sbjct: 1120 EVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPL-----------------VVLPYMKH 1162 Query: 1201 GTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIA 1380 G L+ + I+N K ++ L +++G+ YL S+K VHRD+ N +LD + +K+A Sbjct: 1163 GDLRNF-IRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVA 1221 Query: 1381 DFGVAR----VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDM 1548 DFG+AR E + + TGA + +MA E L + + K DV+SFG+ LWE+ Sbjct: 1222 DFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGA 1281 Query: 1549 -PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 PYPD++ D++ ++ Q R P CP +M KCW + RP E+V + A+ Sbjct: 1282 PPYPDVNTFDITVYLL-QGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAI 1340
>Q09YN5:MET_RABIT Hepatocyte growth factor receptor precursor - Oryctolagus cuniculus| (Rabbit) Length = 1382 Score = 124 bits (312), Expect = 1e-27 Identities = 101/360 (28%), Positives = 162/360 (45%), Gaps = 21/360 (5%) Frame = +1 Query: 709 PEVKFKRTGSLGSSDYVRADKIDL----TSLDIQLEQQLNKKWSKSNIKSLGPKADWEID 876 PE +F + GS V+ DL TS D + L + ++ +L P+ + Sbjct: 1009 PEDQFPNSSQNGSCRQVQYPLTDLSPILTSGDSDISSPLLQNTVHIDLSALNPELVQAVQ 1068 Query: 877 LAKL-------EIRHVIAQGTYGTVYRGTY---DGQQV--AVKLLDWGEDGFATEAETTA 1020 + VI +G +G VY GT DG+++ AVK L+ D Sbjct: 1069 HVVIGPSSLIVHFSEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITD--------IG 1120 Query: 1021 LRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAG 1200 + F E + SHPNV +G + + + VV+ Y+ Sbjct: 1121 EVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPL-----------------VVLPYMKH 1163 Query: 1201 GTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIA 1380 G L+ + I+N K ++ L +++G+ YL S+K VHRD+ N +LD + +K+A Sbjct: 1164 GDLRNF-IRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVA 1222 Query: 1381 DFGVAR----VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDM 1548 DFG+AR E + + TGA + +MA E L + + K DV+SFG+ LWE+ Sbjct: 1223 DFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGA 1282 Query: 1549 -PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 PYPD++ D++ ++ Q R P CP A +M KCW + RP E+V + + Sbjct: 1283 PPYPDVNTFDITVYLL-QGRRLLQPEYCPDALYEVMLKCWHPKAEMRPSFSELVSRISTI 1341
>Q2IBD8:MET_PONPY Hepatocyte growth factor receptor precursor - Pongo pygmaeus| (Orangutan) Length = 1390 Score = 124 bits (312), Expect = 1e-27 Identities = 101/360 (28%), Positives = 162/360 (45%), Gaps = 21/360 (5%) Frame = +1 Query: 709 PEVKFKRTGSLGSSDYVRADKID----LTSLDIQLEQQLNKKWSKSNIKSLGPKADWEID 876 PE +F + GS V+ D LTS D + L + ++ +L P+ + Sbjct: 1008 PEDQFPNSSQNGSCRQVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNPELVQAVQ 1067 Query: 877 LAKL-------EIRHVIAQGTYGTVYRGTY---DGQQV--AVKLLDWGEDGFATEAETTA 1020 + VI +G +G VY GT DG+++ AVK L+ D Sbjct: 1068 HVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITD--------IG 1119 Query: 1021 LRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAG 1200 + F E + SHPNV +G + + + VV+ Y+ Sbjct: 1120 EVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPL-----------------VVLPYMKH 1162 Query: 1201 GTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIA 1380 G L+ + I+N K ++ L +++G+ YL S+K VHRD+ N +LD + +K+A Sbjct: 1163 GDLRNF-IRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVA 1221 Query: 1381 DFGVAR----VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDM 1548 DFG+AR E + + TGA + +MA E L + + K DV+SFG+ LWE+ Sbjct: 1222 DFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGA 1281 Query: 1549 -PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 PYPD++ D++ ++ Q R P CP +M KCW + RP E+V + A+ Sbjct: 1282 PPYPDVNTFDITVYLL-QGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAI 1340
>A0M8R7:MET_PAPAN Hepatocyte growth factor receptor precursor - Papio anubis (Olive| baboon) Length = 1381 Score = 124 bits (312), Expect = 1e-27 Identities = 101/360 (28%), Positives = 162/360 (45%), Gaps = 21/360 (5%) Frame = +1 Query: 709 PEVKFKRTGSLGSSDYVRADKID----LTSLDIQLEQQLNKKWSKSNIKSLGPKADWEID 876 PE +F + GS V+ D LTS D + L + ++ +L P+ + Sbjct: 1008 PEDQFPNSSQNGSCRQVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNPELVQAVQ 1067 Query: 877 LAKL-------EIRHVIAQGTYGTVYRGTY---DGQQV--AVKLLDWGEDGFATEAETTA 1020 + VI +G +G VY GT DG+++ AVK L+ D Sbjct: 1068 HVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITD--------IG 1119 Query: 1021 LRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAG 1200 + F E + SHPNV +G + + + VV+ Y+ Sbjct: 1120 EVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPL-----------------VVLPYMKH 1162 Query: 1201 GTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIA 1380 G L+ + I+N K ++ L +++G+ YL S+K VHRD+ N +LD + +K+A Sbjct: 1163 GDLRNF-IRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVA 1221 Query: 1381 DFGVAR----VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDM 1548 DFG+AR E + + TGA + +MA E L + + K DV+SFG+ LWE+ Sbjct: 1222 DFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGA 1281 Query: 1549 -PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 PYPD++ D++ ++ Q R P CP +M KCW + RP E+V + A+ Sbjct: 1282 PPYPDVNTFDITVYLL-QGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAI 1340
>Q2QLF1:MET_PANTR Hepatocyte growth factor receptor precursor - Pan troglodytes| (Chimpanzee) Length = 1390 Score = 124 bits (312), Expect = 1e-27 Identities = 101/360 (28%), Positives = 162/360 (45%), Gaps = 21/360 (5%) Frame = +1 Query: 709 PEVKFKRTGSLGSSDYVRADKID----LTSLDIQLEQQLNKKWSKSNIKSLGPKADWEID 876 PE +F + GS V+ D LTS D + L + ++ +L P+ + Sbjct: 1008 PEDQFPNSSQNGSCRQVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNPELVQAVQ 1067 Query: 877 LAKL-------EIRHVIAQGTYGTVYRGTY---DGQQV--AVKLLDWGEDGFATEAETTA 1020 + VI +G +G VY GT DG+++ AVK L+ D Sbjct: 1068 HVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITD--------IG 1119 Query: 1021 LRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAG 1200 + F E + SHPNV +G + + + VV+ Y+ Sbjct: 1120 EVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPL-----------------VVLPYMKH 1162 Query: 1201 GTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIA 1380 G L+ + I+N K ++ L +++G+ YL S+K VHRD+ N +LD + +K+A Sbjct: 1163 GDLRNF-IRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVA 1221 Query: 1381 DFGVAR----VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDM 1548 DFG+AR E + + TGA + +MA E L + + K DV+SFG+ LWE+ Sbjct: 1222 DFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGA 1281 Query: 1549 -PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 PYPD++ D++ ++ Q R P CP +M KCW + RP E+V + A+ Sbjct: 1282 PPYPDVNTFDITVYLL-QGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAI 1340
>Q2QL89:MET_MICMU Hepatocyte growth factor receptor precursor - Microcebus murinus| (Lesser mouse lemur) Length = 1382 Score = 124 bits (312), Expect = 1e-27 Identities = 101/360 (28%), Positives = 162/360 (45%), Gaps = 21/360 (5%) Frame = +1 Query: 709 PEVKFKRTGSLGSSDYVRADKIDL----TSLDIQLEQQLNKKWSKSNIKSLGPKADWEID 876 PE +F + GS V+ DL TS D + L + ++ +L P+ + Sbjct: 1009 PEDQFPNSSQNGSCRQVQYPLTDLSPILTSGDSDISSPLLQNTVHIDLSALNPELVQAVQ 1068 Query: 877 LAKL-------EIRHVIAQGTYGTVYRGTY---DGQQV--AVKLLDWGEDGFATEAETTA 1020 + VI +G +G VY GT DG+++ AVK L+ D Sbjct: 1069 HVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITD--------IG 1120 Query: 1021 LRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAG 1200 + F E + SHPNV +G + + + VV+ Y+ Sbjct: 1121 EVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPL-----------------VVLPYMKH 1163 Query: 1201 GTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIA 1380 G L+ + I+N K ++ L +++G+ YL S+K VHRD+ N +LD + +K+A Sbjct: 1164 GDLRNF-IRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVA 1222 Query: 1381 DFGVAR----VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDM 1548 DFG+AR E + + TGA + +MA E L + + K DV+SFG+ LWE+ Sbjct: 1223 DFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGA 1282 Query: 1549 -PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 PYPD++ D++ ++ Q R P CP +M KCW + RP E+V + A+ Sbjct: 1283 PPYPDVNTFDITVYLL-QGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAI 1341
>Q07DY1:MET_HYLLE Hepatocyte growth factor receptor precursor - Hylobates leucogenys| (White-cheeked gibbon) Length = 1390 Score = 124 bits (312), Expect = 1e-27 Identities = 101/360 (28%), Positives = 162/360 (45%), Gaps = 21/360 (5%) Frame = +1 Query: 709 PEVKFKRTGSLGSSDYVRADKID----LTSLDIQLEQQLNKKWSKSNIKSLGPKADWEID 876 PE +F + GS V+ D LTS D + L + ++ +L P+ + Sbjct: 1008 PEDQFPNSSQNGSCRQVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNPELVQAVQ 1067 Query: 877 LAKL-------EIRHVIAQGTYGTVYRGTY---DGQQV--AVKLLDWGEDGFATEAETTA 1020 + VI +G +G VY GT DG+++ AVK L+ D Sbjct: 1068 HVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITD--------IG 1119 Query: 1021 LRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAG 1200 + F E + SHPNV +G + + + VV+ Y+ Sbjct: 1120 EVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPL-----------------VVLPYMKH 1162 Query: 1201 GTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIA 1380 G L+ + I+N K ++ L +++G+ YL S+K VHRD+ N +LD + +K+A Sbjct: 1163 GDLRNF-IRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVA 1221 Query: 1381 DFGVAR----VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDM 1548 DFG+AR E + + TGA + +MA E L + + K DV+SFG+ LWE+ Sbjct: 1222 DFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGA 1281 Query: 1549 -PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 PYPD++ D++ ++ Q R P CP +M KCW + RP E+V + A+ Sbjct: 1282 PPYPDVNTFDITVYLL-QGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAI 1340
>P08581:MET_HUMAN Hepatocyte growth factor receptor precursor - Homo sapiens (Human)| Length = 1390 Score = 124 bits (312), Expect = 1e-27 Identities = 101/360 (28%), Positives = 162/360 (45%), Gaps = 21/360 (5%) Frame = +1 Query: 709 PEVKFKRTGSLGSSDYVRADKID----LTSLDIQLEQQLNKKWSKSNIKSLGPKADWEID 876 PE +F + GS V+ D LTS D + L + ++ +L P+ + Sbjct: 1008 PEDQFPNSSQNGSCRQVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNPELVQAVQ 1067 Query: 877 LAKL-------EIRHVIAQGTYGTVYRGTY---DGQQV--AVKLLDWGEDGFATEAETTA 1020 + VI +G +G VY GT DG+++ AVK L+ D Sbjct: 1068 HVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITD--------IG 1119 Query: 1021 LRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAG 1200 + F E + SHPNV +G + + + VV+ Y+ Sbjct: 1120 EVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPL-----------------VVLPYMKH 1162 Query: 1201 GTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIA 1380 G L+ + I+N K ++ L +++G+ YL S+K VHRD+ N +LD + +K+A Sbjct: 1163 GDLRNF-IRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVA 1221 Query: 1381 DFGVAR----VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDM 1548 DFG+AR E + + TGA + +MA E L + + K DV+SFG+ LWE+ Sbjct: 1222 DFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVVLWELMTRGA 1281 Query: 1549 -PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 PYPD++ D++ ++ Q R P CP +M KCW + RP E+V + A+ Sbjct: 1282 PPYPDVNTFDITVYLL-QGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAI 1340
>Q2IBF2:MET_GORGO Hepatocyte growth factor receptor precursor - Gorilla gorilla gorilla| (Lowland gorilla) Length = 1390 Score = 124 bits (312), Expect = 1e-27 Identities = 101/360 (28%), Positives = 162/360 (45%), Gaps = 21/360 (5%) Frame = +1 Query: 709 PEVKFKRTGSLGSSDYVRADKID----LTSLDIQLEQQLNKKWSKSNIKSLGPKADWEID 876 PE +F + GS V+ D LTS D + L + ++ +L P+ + Sbjct: 1008 PEDQFPNSSQNGSCRQVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNPELVQAVQ 1067 Query: 877 LAKL-------EIRHVIAQGTYGTVYRGTY---DGQQV--AVKLLDWGEDGFATEAETTA 1020 + VI +G +G VY GT DG+++ AVK L+ D Sbjct: 1068 HVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITD--------IG 1119 Query: 1021 LRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAG 1200 + F E + SHPNV +G + + + VV+ Y+ Sbjct: 1120 EVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPL-----------------VVLPYMKH 1162 Query: 1201 GTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIA 1380 G L+ + I+N K ++ L +++G+ YL S+K VHRD+ N +LD + +K+A Sbjct: 1163 GDLRNF-IRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVA 1221 Query: 1381 DFGVAR----VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDM 1548 DFG+AR E + + TGA + +MA E L + + K DV+SFG+ LWE+ Sbjct: 1222 DFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGA 1281 Query: 1549 -PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 PYPD++ D++ ++ Q R P CP +M KCW + RP E+V + A+ Sbjct: 1282 PPYPDVNTFDITVYLL-QGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAI 1340
>Q2IBG7:MET_EULMM Hepatocyte growth factor receptor precursor - Eulemur macaco macaco| (Black lemur) Length = 1382 Score = 124 bits (312), Expect = 1e-27 Identities = 101/360 (28%), Positives = 162/360 (45%), Gaps = 21/360 (5%) Frame = +1 Query: 709 PEVKFKRTGSLGSSDYVRADKIDL----TSLDIQLEQQLNKKWSKSNIKSLGPKADWEID 876 PE +F + GS V+ DL TS D + L + ++ +L P+ + Sbjct: 1009 PEDQFPNSSQNGSCRQVQYPLTDLSPILTSGDSDISSPLLQNTVHIDLSALNPELVQAVQ 1068 Query: 877 LAKL-------EIRHVIAQGTYGTVYRGTY---DGQQV--AVKLLDWGEDGFATEAETTA 1020 + VI +G +G VY GT DG+++ AVK L+ D Sbjct: 1069 HVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITD--------IG 1120 Query: 1021 LRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAG 1200 + F E + SHPNV +G + + + VV+ Y+ Sbjct: 1121 EVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPL-----------------VVLPYMKH 1163 Query: 1201 GTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIA 1380 G L+ + I+N K ++ L +++G+ YL S+K VHRD+ N +LD + +K+A Sbjct: 1164 GDLRNF-IRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVA 1222 Query: 1381 DFGVAR----VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDM 1548 DFG+AR E + + TGA + +MA E L + + K DV+SFG+ LWE+ Sbjct: 1223 DFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGA 1282 Query: 1549 -PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 PYPD++ D++ ++ Q R P CP +M KCW + RP E+V + A+ Sbjct: 1283 PPYPDVNTFDITVYLL-QGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAI 1341
>Q07E48:MET_DASNO Hepatocyte growth factor receptor precursor - Dasypus novemcinctus| (Nine-banded armadillo) Length = 1381 Score = 124 bits (312), Expect = 1e-27 Identities = 101/360 (28%), Positives = 163/360 (45%), Gaps = 21/360 (5%) Frame = +1 Query: 709 PEVKFKRTGSLGSSDYVRADKIDL----TSLDIQLEQQLNKKWSKSNIKSLGPKADWEID 876 PE +F + GS V+ +DL TS D + L + ++ +L P+ E+ Sbjct: 1009 PEDQFPNSSQNGSCRQVQYPLMDLSPILTSGDSDISSPLLQNVVHIDLSALNPELVQEVQ 1068 Query: 877 LAKL-------EIRHVIAQGTYGTVYRGTY---DGQQV--AVKLLDWGEDGFATEAETTA 1020 + VI +G +G VY GT D +++ AVK L+ D Sbjct: 1069 HVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDSDDKKIHCAVKSLNRITD--------IG 1120 Query: 1021 LRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAG 1200 + F E + SHPNV +G + + + VV+ Y+ Sbjct: 1121 EVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPL-----------------VVLPYMKH 1163 Query: 1201 GTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIA 1380 G L+ + I+N K ++ L +++G+ YL S+K VHRD+ N +LD + +K+A Sbjct: 1164 GDLRNF-IRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVA 1222 Query: 1381 DFGVAR----VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDM 1548 DFG+AR E + + TGA + +MA E L + + K DV+SFG+ LWE+ Sbjct: 1223 DFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGA 1282 Query: 1549 -PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 PYPD++ D++ ++ Q R P CP +M KCW + RP E+V + A+ Sbjct: 1283 PPYPDVNTFDITVYLL-QGRRLLQPEYCPDRLYEVMLKCWHPKAEMRPSFSELVSRISAI 1341
>Q07DZ1:MET_COLGU Hepatocyte growth factor receptor precursor - Colobus guereza| (Black-and-white colobus monkey) Length = 1381 Score = 124 bits (312), Expect = 1e-27 Identities = 101/360 (28%), Positives = 162/360 (45%), Gaps = 21/360 (5%) Frame = +1 Query: 709 PEVKFKRTGSLGSSDYVRADKID----LTSLDIQLEQQLNKKWSKSNIKSLGPKADWEID 876 PE +F + GS V+ D LTS D + L + ++ +L P+ + Sbjct: 1008 PEDQFPNSSQNGSCRQVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNPELVQAVQ 1067 Query: 877 LAKL-------EIRHVIAQGTYGTVYRGTY---DGQQV--AVKLLDWGEDGFATEAETTA 1020 + VI +G +G VY GT DG+++ AVK L+ D Sbjct: 1068 HVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITD--------IG 1119 Query: 1021 LRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAG 1200 + F E + SHPNV +G + + + VV+ Y+ Sbjct: 1120 EVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPL-----------------VVLPYMKH 1162 Query: 1201 GTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIA 1380 G L+ + I+N K ++ L +++G+ YL S+K VHRD+ N +LD + +K+A Sbjct: 1163 GDLRNF-IRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVA 1221 Query: 1381 DFGVAR----VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDM 1548 DFG+AR E + + TGA + +MA E L + + K DV+SFG+ LWE+ Sbjct: 1222 DFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGA 1281 Query: 1549 -PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 PYPD++ D++ ++ Q R P CP +M KCW + RP E+V + A+ Sbjct: 1282 PPYPDVNTFDITVYLL-QGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAI 1340
>Q2QLG5:MET_CALJA Hepatocyte growth factor receptor precursor - Callithrix jacchus| (Common marmoset) Length = 1381 Score = 124 bits (312), Expect = 1e-27 Identities = 101/360 (28%), Positives = 162/360 (45%), Gaps = 21/360 (5%) Frame = +1 Query: 709 PEVKFKRTGSLGSSDYVRADKID----LTSLDIQLEQQLNKKWSKSNIKSLGPKADWEID 876 PE +F + GS V+ D LTS D + L + ++ +L P+ + Sbjct: 1008 PEDQFPNSSQNGSCRQVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNPELVQAVQ 1067 Query: 877 LAKL-------EIRHVIAQGTYGTVYRGTY---DGQQV--AVKLLDWGEDGFATEAETTA 1020 + VI +G +G VY GT DG+++ AVK L+ D Sbjct: 1068 HVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITD--------IG 1119 Query: 1021 LRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAG 1200 + F E + SHPNV +G + + + VV+ Y+ Sbjct: 1120 EVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPL-----------------VVLPYMKH 1162 Query: 1201 GTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIA 1380 G L+ + I+N K ++ L +++G+ YL S+K VHRD+ N +LD + +K+A Sbjct: 1163 GDLRNF-IRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVA 1221 Query: 1381 DFGVAR----VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDM 1548 DFG+AR E + + TGA + +MA E L + + K DV+SFG+ LWE+ Sbjct: 1222 DFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGA 1281 Query: 1549 -PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 PYPD++ D++ ++ Q R P CP +M KCW + RP E+V + A+ Sbjct: 1282 PPYPDVNTFDITVYLL-QGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAI 1340
>Q09YL1:MET_ATEGE Hepatocyte growth factor receptor precursor - Ateles geoffroyi| (Black-handed spider monkey) Length = 1381 Score = 124 bits (312), Expect = 1e-27 Identities = 101/360 (28%), Positives = 162/360 (45%), Gaps = 21/360 (5%) Frame = +1 Query: 709 PEVKFKRTGSLGSSDYVRADKID----LTSLDIQLEQQLNKKWSKSNIKSLGPKADWEID 876 PE +F + GS V+ D LTS D + L + ++ +L P+ + Sbjct: 1008 PEDQFPNSSQNGSCRQVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNPELVQAVQ 1067 Query: 877 LAKL-------EIRHVIAQGTYGTVYRGTY---DGQQV--AVKLLDWGEDGFATEAETTA 1020 + VI +G +G VY GT DG+++ AVK L+ D Sbjct: 1068 HVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITD--------IG 1119 Query: 1021 LRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAG 1200 + F E + SHPNV +G + + + VV+ Y+ Sbjct: 1120 EVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPL-----------------VVLPYMKH 1162 Query: 1201 GTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIA 1380 G L+ + I+N K ++ L +++G+ YL S+K VHRD+ N +LD + +K+A Sbjct: 1163 GDLRNF-IRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVA 1221 Query: 1381 DFGVAR----VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDM 1548 DFG+AR E + + TGA + +MA E L + + K DV+SFG+ LWE+ Sbjct: 1222 DFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGA 1281 Query: 1549 -PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 PYPD++ D++ ++ Q R P CP +M KCW + RP E+V + A+ Sbjct: 1282 PPYPDVNTFDITVYLL-QGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAI 1340
>Q07DV8:MET_AOTNA Hepatocyte growth factor receptor precursor - Aotus nancymaae (Ma's| night monkey) Length = 1381 Score = 124 bits (312), Expect = 1e-27 Identities = 101/360 (28%), Positives = 162/360 (45%), Gaps = 21/360 (5%) Frame = +1 Query: 709 PEVKFKRTGSLGSSDYVRADKID----LTSLDIQLEQQLNKKWSKSNIKSLGPKADWEID 876 PE +F + GS V+ D LTS D + L + ++ +L P+ + Sbjct: 1008 PEDQFPNSSQNGSCRQVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNPELVQAVQ 1067 Query: 877 LAKL-------EIRHVIAQGTYGTVYRGTY---DGQQV--AVKLLDWGEDGFATEAETTA 1020 + VI +G +G VY GT DG+++ AVK L+ D Sbjct: 1068 HVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITD--------IG 1119 Query: 1021 LRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAG 1200 + F E + SHPNV +G + + + VV+ Y+ Sbjct: 1120 EVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPL-----------------VVLPYMKH 1162 Query: 1201 GTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIA 1380 G L+ + I+N K ++ L +++G+ YL S+K VHRD+ N +LD + +K+A Sbjct: 1163 GDLRNF-IRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVA 1221 Query: 1381 DFGVAR----VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDM 1548 DFG+AR E + + TGA + +MA E L + + K DV+SFG+ LWE+ Sbjct: 1222 DFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGA 1281 Query: 1549 -PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 PYPD++ D++ ++ Q R P CP +M KCW + RP E+V + A+ Sbjct: 1282 PPYPDVNTFDITVYLL-QGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAI 1340
>P07332:FES_HUMAN Proto-oncogene tyrosine-protein kinase Fes/Fps - Homo sapiens (Human)| Length = 822 Score = 124 bits (312), Expect = 1e-27 Identities = 91/316 (28%), Positives = 145/316 (45%), Gaps = 5/316 (1%) Frame = +1 Query: 793 IQLEQQLNKKWSKSNIKSLGPKADWEIDLAKLEIRHVIAQGTYGTVYRGTY--DGQQVAV 966 + +Q L KK S + PK W ++ L + I +G +G V+ G D VAV Sbjct: 531 LSTQQPLTKK-SGVVLHRAVPKDKWVLNHEDLVLGEQIGRGNFGEVFSGRLRADNTLVAV 589 Query: 967 KLLDWGEDGFATEAETTALRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGA 1146 K E L+ F QE + + SHPN+ + +G K P+ Sbjct: 590 KS--------CRETLPPDLKAKFLQEARILKQYSHPNIVRLIGVCTQ----KQPIY---- 633 Query: 1147 RANLPARACCVVVEYLAGGTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHR 1326 +V+E + GG +L + +L K ++Q+ D + G+ YL S+ +HR Sbjct: 634 ----------IVMELVQGGDFLTFL-RTEGARLRVKTLLQMVGDAAAGMEYLESKCCIHR 682 Query: 1327 DVKTENMLLDTQRNLKIADFGVARVEAQNPKDMTGATG--TLGYMAPEVLDGKPYNRKCD 1500 D+ N L+ + LKI+DFG++R EA +G + + APE L+ Y+ + D Sbjct: 683 DLAARNCLVTEKNVLKISDFGMSREEADGVYAASGGLRQVPVKWTAPEALNYGRYSSESD 742 Query: 1501 VYSFGICLWEVYCCD-MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNP 1677 V+SFGI LWE + PYP+LS + V + R P CP A +M +CW P Sbjct: 743 VWSFGILLWETFSLGASPYPNLS-NQQTREFVEKGGRLPCPELCPDAVFRLMEQCWAYEP 801 Query: 1678 DKRPDMDEVVQLMEAL 1725 +RP + Q ++++ Sbjct: 802 GQRPSFSTIYQELQSI 817
>P97523:MET_RAT Hepatocyte growth factor receptor precursor - Rattus norvegicus (Rat)| Length = 1382 Score = 124 bits (311), Expect = 2e-27 Identities = 101/360 (28%), Positives = 166/360 (46%), Gaps = 21/360 (5%) Frame = +1 Query: 709 PEVKFKRTGSLGSSDYVRADKIDL----TSLDIQLEQQLNKKWSKSNIKSLGPKADWEID 876 PE +F + G+ V+ DL TS D + L + ++ +L P+ + Sbjct: 1009 PEDQFPNSSQNGACRQVQYLLTDLSPILTSGDSDISSPLLQNTVHIDLSALNPELVQAVP 1068 Query: 877 LAKL-------EIRHVIAQGTYGTVYRGTY---DGQQV--AVKLLDWGEDGFATEAETTA 1020 + VI +G +G VY GT DG+++ AVK L+ T+ E + Sbjct: 1069 HVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDSDGKKIHCAVKSLNR-----ITDIEEVS 1123 Query: 1021 LRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAG 1200 F E + SHPNV +G + + + VV+ Y+ Sbjct: 1124 ---QFLTEGIIMKDFSHPNVLSLLGICLRSEGSPL-----------------VVLPYMKH 1163 Query: 1201 GTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIA 1380 G L+ + I+N K ++ L +++G+ YL S+K VHRD+ N +LD + +K+A Sbjct: 1164 GDLRNF-IRNETHNPTVKDLIGFGLQVAKGMKYLVSKKFVHRDLAARNCMLDEKFTVKVA 1222 Query: 1381 DFGVAR----VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDM 1548 DFG+AR E + + TGA + +MA E L + + K DV+SFG+ LWE+ Sbjct: 1223 DFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGA 1282 Query: 1549 -PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 PYPD++ D++ ++ Q R P CP A +M KCW + RP + E+V + ++ Sbjct: 1283 PPYPDVNTFDITIYLL-QGRRLLQPEYCPDALYEVMLKCWHPKAEMRPSVSELVSRISSI 1341
>Q2QLH6:MET_OTOGA Hepatocyte growth factor receptor precursor - Otolemur garnettii| (Small-eared galago) (Garnett's greater bushbaby) Length = 1382 Score = 124 bits (311), Expect = 2e-27 Identities = 101/360 (28%), Positives = 161/360 (44%), Gaps = 21/360 (5%) Frame = +1 Query: 709 PEVKFKRTGSLGSSDYVRADKIDL----TSLDIQLEQQLNKKWSKSNIKSLGPKADWEID 876 PE +F + GS V+ DL TS D + L + ++ +L P+ + Sbjct: 1009 PEDQFPNSSQNGSCRQVQYPLTDLSPILTSGDSDISSPLLQNTVHIDLSALNPELVQAVQ 1068 Query: 877 LAKL-------EIRHVIAQGTYGTVYRGTY---DGQQV--AVKLLDWGEDGFATEAETTA 1020 + VI +G +G VY GT DG+++ AVK L+ D Sbjct: 1069 HVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITD--------IG 1120 Query: 1021 LRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAG 1200 + F E + SHPNV +G + + + VV+ Y+ Sbjct: 1121 EVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPL-----------------VVLPYMKH 1163 Query: 1201 GTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIA 1380 G L+ + I+N K ++ L +++G+ YL S+K VHRD+ N +LD +K+A Sbjct: 1164 GDLRNF-IRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDENFTVKVA 1222 Query: 1381 DFGVAR----VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDM 1548 DFG+AR E + + TGA + +MA E L + + K DV+SFG+ LWE+ Sbjct: 1223 DFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGA 1282 Query: 1549 -PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 PYPD++ D++ ++ Q R P CP +M KCW + RP E+V + A+ Sbjct: 1283 PPYPDVNTFDITVYLL-QGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAI 1341
>Q2QLC0:MET_CALMO Hepatocyte growth factor receptor precursor - Callicebus moloch| (Dusky titi monkey) Length = 1381 Score = 124 bits (310), Expect = 2e-27 Identities = 101/360 (28%), Positives = 162/360 (45%), Gaps = 21/360 (5%) Frame = +1 Query: 709 PEVKFKRTGSLGSSDYVRADKID----LTSLDIQLEQQLNKKWSKSNIKSLGPKADWEID 876 PE +F + GS V+ D LTS D + L + ++ +L P+ + Sbjct: 1008 PEDQFPNSSQNGSCRQVQYPLPDMSPILTSGDSDISSPLLQNTVHIDLSALNPELVQAVQ 1067 Query: 877 LAKL-------EIRHVIAQGTYGTVYRGTY---DGQQV--AVKLLDWGEDGFATEAETTA 1020 + VI +G +G VY GT DG+++ AVK L+ D Sbjct: 1068 HVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITD--------IG 1119 Query: 1021 LRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAG 1200 + F E + SHPNV +G + + + VV+ Y+ Sbjct: 1120 EVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPL-----------------VVLPYMKH 1162 Query: 1201 GTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIA 1380 G L+ + I+N K ++ L +++G+ YL S+K VHRD+ N +LD + +K+A Sbjct: 1163 GDLRNF-IRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVA 1221 Query: 1381 DFGVAR----VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDM 1548 DFG+AR E + + TGA + +MA E L + + K DV+SFG+ LWE+ Sbjct: 1222 DFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGA 1281 Query: 1549 -PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 PYPD++ D++ ++ Q R P CP +M KCW + RP E+V + A+ Sbjct: 1282 PPYPDVNTFDITVYLL-QGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAI 1340
>P14238:FES_FELCA Proto-oncogene tyrosine-protein kinase Fes/Fps - Felis silvestris| catus (Cat) Length = 820 Score = 124 bits (310), Expect = 2e-27 Identities = 90/316 (28%), Positives = 146/316 (46%), Gaps = 5/316 (1%) Frame = +1 Query: 793 IQLEQQLNKKWSKSNIKSLGPKADWEIDLAKLEIRHVIAQGTYGTVYRGTY--DGQQVAV 966 ++ +Q L KK S + PK W ++ L + I +G +G V+ G D VAV Sbjct: 529 LRSQQPLTKK-SGIVLNRAVPKDKWVLNHEDLVLGEQIGRGNFGEVFSGRLRADNTLVAV 587 Query: 967 KLLDWGEDGFATEAETTALRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGA 1146 K E ++ F QE + + SHPN+ + +G K P+ Sbjct: 588 KS--------CRETLPPDIKAKFLQEAKILKQYSHPNIVRLIGVCTQ----KQPIY---- 631 Query: 1147 RANLPARACCVVVEYLAGGTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHR 1326 +V+E + GG +L + +L K ++Q+ D + G+ YL S+ +HR Sbjct: 632 ----------IVMELVQGGDFLTFL-RTEGARLRMKTLLQMVGDAAAGMEYLESKCCIHR 680 Query: 1327 DVKTENMLLDTQRNLKIADFGVARVEAQNPKDMTGATG--TLGYMAPEVLDGKPYNRKCD 1500 D+ N L+ + LKI+DFG++R EA +G + + APE L+ Y+ + D Sbjct: 681 DLAARNCLVTEKNVLKISDFGMSREEADGIYAASGGLRQVPVKWTAPEALNYGRYSSESD 740 Query: 1501 VYSFGICLWEVYCCD-MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNP 1677 V+SFGI LWE + PYP+LS + V + R P CP A +M +CW P Sbjct: 741 VWSFGILLWETFSLGASPYPNLS-NQQTREFVEKGGRLPCPELCPDAVFRLMEQCWAYEP 799 Query: 1678 DKRPDMDEVVQLMEAL 1725 +RP + Q ++++ Sbjct: 800 GQRPSFSAIYQELQSI 815
>P11345:RAF1_RAT RAF proto-oncogene serine/threonine-protein kinase - Rattus| norvegicus (Rat) Length = 648 Score = 123 bits (309), Expect = 3e-27 Identities = 86/299 (28%), Positives = 154/299 (51%), Gaps = 9/299 (3%) Frame = +1 Query: 865 WEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFATEAETTALRTSFKQE 1044 WEI+ +++ + I G++GTVY+G + G VAVK+L + T +F+ E Sbjct: 342 WEIEASEVMLSTRIGSGSFGTVYKGKWHGD-VAVKILKVVDP-------TPEQLQAFRNE 393 Query: 1045 VAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYLI 1224 VAV K H N+ F+G DN A +V ++ G +L ++L Sbjct: 394 VAVLRKTRHVNILLFMGYM---------TKDNLA----------IVTQWCEGSSLYKHLH 434 Query: 1225 KNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGVARVE 1404 + ++++ +A ++G+ YLH++ I+HRD+K+ N+ L +KI DFG+A V+ Sbjct: 435 VQETKFQMFQLI-DIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGLATVK 493 Query: 1405 AQ--NPKDMTGATGTLGYMAPEVL---DGKPYNRKCDVYSFGICLWEVYCCDMPYPDLSF 1569 ++ + + TG++ +MAPEV+ D P++ + DVYS+GI L+E+ ++PY ++ Sbjct: 494 SRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSFQSDVYSYGIVLYELMTGELPYSHINN 553 Query: 1570 ADVSSAVVHQN-LRPDIPRC---CPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDTS 1734 D +V + PD+ R CP A ++ C ++RP +++ +E L S Sbjct: 554 RDQIIFMVGRGYASPDLSRLYKNCPKAMKRLVADCVKKVKEERPLFPQILSSIELLQHS 612
>Q99N57:RAF1_MOUSE RAF proto-oncogene serine/threonine-protein kinase - Mus musculus| (Mouse) Length = 648 Score = 123 bits (309), Expect = 3e-27 Identities = 86/299 (28%), Positives = 154/299 (51%), Gaps = 9/299 (3%) Frame = +1 Query: 865 WEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFATEAETTALRTSFKQE 1044 WEI+ +++ + I G++GTVY+G + G VAVK+L + T +F+ E Sbjct: 342 WEIEASEVMLSTRIGSGSFGTVYKGKWHGD-VAVKILKVVDP-------TPEQLQAFRNE 393 Query: 1045 VAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYLI 1224 VAV K H N+ F+G DN A +V ++ G +L ++L Sbjct: 394 VAVLRKTRHVNILLFMGYM---------TKDNLA----------IVTQWCEGSSLYKHLH 434 Query: 1225 KNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGVARVE 1404 + ++++ +A ++G+ YLH++ I+HRD+K+ N+ L +KI DFG+A V+ Sbjct: 435 VQETKFQMFQLI-DIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGLATVK 493 Query: 1405 AQ--NPKDMTGATGTLGYMAPEVL---DGKPYNRKCDVYSFGICLWEVYCCDMPYPDLSF 1569 ++ + + TG++ +MAPEV+ D P++ + DVYS+GI L+E+ ++PY ++ Sbjct: 494 SRWSGSQQVEQPTGSVLWMAPEVIRMQDDNPFSFQSDVYSYGIVLYELMAGELPYAHINN 553 Query: 1570 ADVSSAVVHQN-LRPDIPRC---CPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDTS 1734 D +V + PD+ R CP A ++ C ++RP +++ +E L S Sbjct: 554 RDQIIFMVGRGYASPDLSRLYKNCPKAMKRLVADCVKKVKEERPLFPQILSSIELLQHS 612
>Q2IBA6:MET_CERAE Hepatocyte growth factor receptor precursor - Cercopithecus aethiops| (Green monkey) (Grivet) Length = 1381 Score = 123 bits (309), Expect = 3e-27 Identities = 101/360 (28%), Positives = 161/360 (44%), Gaps = 21/360 (5%) Frame = +1 Query: 709 PEVKFKRTGSLGSSDYVRADKID----LTSLDIQLEQQLNKKWSKSNIKSLGPKADWEID 876 PE +F + GS V+ D LTS D + L + ++ L P+ + Sbjct: 1008 PEDQFPNSSQNGSCRQVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSVLNPELVQAVQ 1067 Query: 877 LAKL-------EIRHVIAQGTYGTVYRGTY---DGQQV--AVKLLDWGEDGFATEAETTA 1020 + VI +G +G VY GT DG+++ AVK L+ D Sbjct: 1068 HVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITD--------IG 1119 Query: 1021 LRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAG 1200 + F E + SHPNV +G + + + VV+ Y+ Sbjct: 1120 EVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPL-----------------VVLPYMKH 1162 Query: 1201 GTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIA 1380 G L+ + I+N K ++ L +++G+ YL S+K VHRD+ N +LD + +K+A Sbjct: 1163 GDLRNF-IRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVA 1221 Query: 1381 DFGVAR----VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDM 1548 DFG+AR E + + TGA + +MA E L + + K DV+SFG+ LWE+ Sbjct: 1222 DFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGA 1281 Query: 1549 -PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 PYPD++ D++ ++ Q R P CP +M KCW + RP E+V + A+ Sbjct: 1282 PPYPDVNTFDITVYLL-QGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAI 1340
>Q2IBC0:MET_RHIFE Hepatocyte growth factor receptor precursor - Rhinolophus| ferrumequinum (Greater horseshoe bat) Length = 1381 Score = 122 bits (307), Expect = 5e-27 Identities = 98/360 (27%), Positives = 163/360 (45%), Gaps = 21/360 (5%) Frame = +1 Query: 709 PEVKFKRTGSLGSSDYVRADKIDLTSL----DIQLEQQLNKKWSKSNIKSLGPKADWEID 876 PE +F + GS V+ +DL+ + D + L + + ++ +L P+ + Sbjct: 1008 PEDQFANSSQNGSCRQVQCPLMDLSPILPGGDSDISSPLLQNTVRIDLSALNPELVQAVQ 1067 Query: 877 LAKL-------EIRHVIAQGTYGTVYRGTY---DGQQV--AVKLLDWGEDGFATEAETTA 1020 + VI +G +G VY GT D +++ AVK L+ D Sbjct: 1068 HVVIGPSRLIVHFNEVIGRGHFGCVYHGTLLDNDDKKIHCAVKSLNRITD--------IG 1119 Query: 1021 LRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAG 1200 + F E + SHPNV +G + + + VV+ Y+ Sbjct: 1120 EVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPL-----------------VVLPYMKH 1162 Query: 1201 GTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIA 1380 G L+ + I+N K ++ L +++G+ YL S+K VHRD+ N +LD +K+A Sbjct: 1163 GDLRNF-IRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDENFTVKVA 1221 Query: 1381 DFGVAR----VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDM 1548 DFG+AR E + + TGA + +MA E L + + K DV+SFG+ LWE+ Sbjct: 1222 DFGLARDVYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGA 1281 Query: 1549 -PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 PYPD++ D++ ++ Q R P CP +M KCW ++RP E+V + A+ Sbjct: 1282 PPYPDVNTFDITVYLL-QGRRLLQPEYCPDHLYEVMLKCWHPKAEQRPSFAELVSRISAI 1340
>Q09YK0:MET_MUNMU Hepatocyte growth factor receptor precursor - Muntiacus muntjak| (Barking deer) (Indian muntjac) Length = 1382 Score = 122 bits (307), Expect = 5e-27 Identities = 101/360 (28%), Positives = 161/360 (44%), Gaps = 21/360 (5%) Frame = +1 Query: 709 PEVKFKRTGSLGSSDYVRADKIDL----TSLDIQLEQQLNKKWSKSNIKSLGPKADWEID 876 PE +F GS V+ DL TS D + L + ++ +L P+ + Sbjct: 1009 PEDQFPNASQNGSCRQVQYPLTDLSPILTSGDSDVSSPLLQNTVHIDLSALNPELVQAVQ 1068 Query: 877 LAKL-------EIRHVIAQGTYGTVYRGTY---DGQQV--AVKLLDWGEDGFATEAETTA 1020 + VI +G +G VY GT D +++ AVK L+ D Sbjct: 1069 HVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDDKKIHCAVKSLNRITD--------IG 1120 Query: 1021 LRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAG 1200 + F E + SHPNV +G + + + VV+ Y+ Sbjct: 1121 EVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPL-----------------VVLPYMKH 1163 Query: 1201 GTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIA 1380 G L+ + I+N K ++ L +++G+ YL S+K VHRD+ N +LD + +K+A Sbjct: 1164 GDLRNF-IRNETHNPTVKDLIGFGLQVAKGMEYLASKKFVHRDLAARNCMLDEKFTVKVA 1222 Query: 1381 DFGVAR----VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDM 1548 DFG+AR E + + TGA + +MA E L + + K DV+SFG+ LWE+ Sbjct: 1223 DFGLARDVYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGA 1282 Query: 1549 -PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 PYPD++ D++ ++ Q R P CP A +M KCW + RP E+V + A+ Sbjct: 1283 PPYPDVNTFDITVYLL-QGRRLLQPEYCPDALYEVMLKCWHPKAELRPSFSELVSRISAI 1341
>P00543:FES_FSVST Tyrosine-protein kinase transforming protein Fes - Feline sarcoma| virus (strain Snyder-Theilen) Length = 477 Score = 122 bits (307), Expect = 5e-27 Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 5/316 (1%) Frame = +1 Query: 793 IQLEQQLNKKWSKSNIKSLGPKADWEIDLAKLEIRHVIAQGTYGTVYRGTY--DGQQVAV 966 ++ +Q L KK S + PK W ++ L + I +G +G V+ G D VAV Sbjct: 186 LRSQQPLTKK-SGIVLNRAVPKDKWVLNHEDLVLGEQIGRGNFGEVFSGRLRADNTLVAV 244 Query: 967 KLLDWGEDGFATEAETTALRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGA 1146 K E ++ F QE + + SHPN+ + +G K P+ Sbjct: 245 KS--------CRETLPPDIKAKFLQEAKILKQYSHPNIVRLIGVCTQ----KQPIY---- 288 Query: 1147 RANLPARACCVVVEYLAGGTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHR 1326 +V+E + GG +L + +L K ++Q+ D + G+ YL S+ +HR Sbjct: 289 ----------IVMELVQGGDFLTFL-RTEGARLRMKTLLQMVGDAAAGMEYLESKCCIHR 337 Query: 1327 DVKTENMLLDTQRNLKIADFGVARVEAQNPKDMTGATG--TLGYMAPEVLDGKPYNRKCD 1500 D+ N L+ + LKI+DFG++R EA +G + + APE L+ Y+ + D Sbjct: 338 DLAARNCLVTEKNVLKISDFGMSREEADGVYAASGGLRLVPVKWTAPEALNYGRYSSESD 397 Query: 1501 VYSFGICLWEVYCCD-MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNP 1677 V+SFGI LWE + PYP+LS + V + R P CP A +M +CW P Sbjct: 398 VWSFGILLWETFSLGASPYPNLS-NQQTREFVEKGGRLPCPELCPDAVFRLMEQCWAYEP 456 Query: 1678 DKRPDMDEVVQLMEAL 1725 +RP Q ++++ Sbjct: 457 GQRPSFSAFYQELQSI 472
>P05625:RAF1_CHICK RAF proto-oncogene serine/threonine-protein kinase - Gallus gallus| (Chicken) Length = 647 Score = 122 bits (306), Expect = 6e-27 Identities = 85/299 (28%), Positives = 154/299 (51%), Gaps = 9/299 (3%) Frame = +1 Query: 865 WEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFATEAETTALRTSFKQE 1044 WEI+ +++ + I G++GTVY+G + G VAVK+L + T +F+ E Sbjct: 342 WEIEASEVMLSTRIGSGSFGTVYKGKWHGD-VAVKILKVVDP-------TPEQFQAFRNE 393 Query: 1045 VAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYLI 1224 VAV K H N+ F+G DN A +V ++ G +L ++L Sbjct: 394 VAVLRKTRHVNILLFMGYM---------TKDNLA----------IVTQWCEGSSLYKHLH 434 Query: 1225 KNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGVARVE 1404 + ++++ +A ++G+ YLH++ I+HRD+K+ N+ L +KI DFG+A V+ Sbjct: 435 VQETKFQMFQLI-DIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGLATVK 493 Query: 1405 AQ--NPKDMTGATGTLGYMAPEVL---DGKPYNRKCDVYSFGICLWEVYCCDMPYPDLSF 1569 ++ + + TG++ +MAPEV+ D P++ + DVYS+GI L+E+ ++PY ++ Sbjct: 494 SRWSGSQQVEQPTGSILWMAPEVIRMQDSNPFSFQSDVYSYGIVLYELMTGELPYSHINN 553 Query: 1570 ADVSSAVVHQN-LRPDIPRC---CPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDTS 1734 D +V + PD+ + CP A ++ C ++RP +++ +E L S Sbjct: 554 RDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCLKKVREERPLFPQILSSIELLQHS 612
>Q2QLE0:MET_PIG Hepatocyte growth factor receptor precursor - Sus scrofa (Pig)| Length = 1381 Score = 122 bits (306), Expect = 6e-27 Identities = 104/377 (27%), Positives = 166/377 (44%), Gaps = 26/377 (6%) Frame = +1 Query: 673 PRAKMASSA-----GDLPEVKFKRTGSLGSSDYVRADKIDL----TSLDIQLEQQLNKKW 825 P +M SS PE +F + GS V+ DL TS D + L + Sbjct: 991 PTTEMVSSEPVDYRATFPEDQFPNSSQNGSCRQVQYPLTDLSPILTSGDSDISSPLLQNT 1050 Query: 826 SKSNIKSLGPKADWEIDLAKL-------EIRHVIAQGTYGTVYRGTY---DGQQV--AVK 969 ++ +L P+ + + VI +G +G VY GT D +++ AVK Sbjct: 1051 VHIDLSALNPELVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDDKKIHCAVK 1110 Query: 970 LLDWGEDGFATEAETTALRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGAR 1149 L+ D + F E + SHPNV +G + + + Sbjct: 1111 SLNRITD--------IGEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPL-------- 1154 Query: 1150 ANLPARACCVVVEYLAGGTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRD 1329 VV+ Y+ G L+ + I+N K ++ L +++G+ YL S+K VHRD Sbjct: 1155 ---------VVLPYMKHGDLRNF-IRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRD 1204 Query: 1330 VKTENMLLDTQRNLKIADFGVAR----VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKC 1497 + N +LD + +K+ADFG+AR E + + TGA + +MA E L + + K Sbjct: 1205 LAARNCMLDEKFTVKVADFGLARDVYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKS 1264 Query: 1498 DVYSFGICLWEVYCCDM-PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGN 1674 DV+SFG+ LWE+ PYPD++ D++ ++ Q R P CP +M KCW Sbjct: 1265 DVWSFGVLLWELMTRGAPPYPDVNTFDITVYLL-QGRRLLQPEYCPDPLYEVMLKCWHPR 1323 Query: 1675 PDKRPDMDEVVQLMEAL 1725 + RP E+V + A+ Sbjct: 1324 AELRPSFSELVSRISAI 1340
>Q5R5M7:RAF1_PONPY RAF proto-oncogene serine/threonine-protein kinase - Pongo pygmaeus| (Orangutan) Length = 648 Score = 122 bits (305), Expect = 8e-27 Identities = 85/299 (28%), Positives = 154/299 (51%), Gaps = 9/299 (3%) Frame = +1 Query: 865 WEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFATEAETTALRTSFKQE 1044 WEI+ +++ + I G++GTVY+G + G VAVK+L + T +F+ E Sbjct: 342 WEIEASEVMLSTRIGSGSFGTVYKGKWHGD-VAVKILKVVDP-------TPEQFQAFRNE 393 Query: 1045 VAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYLI 1224 VAV K H N+ F+G DN A +V ++ G +L ++L Sbjct: 394 VAVLRKTRHVNILLFMGYM---------TKDNLA----------IVTQWCEGSSLYKHLH 434 Query: 1225 KNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGVARVE 1404 + ++++ +A ++G+ YLH++ I+HRD+K+ N+ L +KI DFG+A V+ Sbjct: 435 VQETKFQMFQLI-DIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGLATVK 493 Query: 1405 AQ--NPKDMTGATGTLGYMAPEVL---DGKPYNRKCDVYSFGICLWEVYCCDMPYPDLSF 1569 ++ + + TG++ +MAPEV+ D P++ + DVYS+GI L+E+ ++PY ++ Sbjct: 494 SRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSFQSDVYSYGIVLYELMTGELPYSHINN 553 Query: 1570 ADVSSAVVHQN-LRPDIPRC---CPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDTS 1734 D +V + PD+ + CP A ++ C ++RP +++ +E L S Sbjct: 554 RDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCVKKVKEERPLFPQILSSIELLQHS 612
>P04049:RAF1_HUMAN RAF proto-oncogene serine/threonine-protein kinase - Homo sapiens| (Human) Length = 648 Score = 122 bits (305), Expect = 8e-27 Identities = 85/299 (28%), Positives = 154/299 (51%), Gaps = 9/299 (3%) Frame = +1 Query: 865 WEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFATEAETTALRTSFKQE 1044 WEI+ +++ + I G++GTVY+G + G VAVK+L + T +F+ E Sbjct: 342 WEIEASEVMLSTRIGSGSFGTVYKGKWHGD-VAVKILKVVDP-------TPEQFQAFRNE 393 Query: 1045 VAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYLI 1224 VAV K H N+ F+G DN A +V ++ G +L ++L Sbjct: 394 VAVLRKTRHVNILLFMGYM---------TKDNLA----------IVTQWCEGSSLYKHLH 434 Query: 1225 KNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGVARVE 1404 + ++++ +A ++G+ YLH++ I+HRD+K+ N+ L +KI DFG+A V+ Sbjct: 435 VQETKFQMFQLI-DIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGLATVK 493 Query: 1405 AQ--NPKDMTGATGTLGYMAPEVL---DGKPYNRKCDVYSFGICLWEVYCCDMPYPDLSF 1569 ++ + + TG++ +MAPEV+ D P++ + DVYS+GI L+E+ ++PY ++ Sbjct: 494 SRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSFQSDVYSYGIVLYELMTGELPYSHINN 553 Query: 1570 ADVSSAVVHQN-LRPDIPRC---CPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDTS 1734 D +V + PD+ + CP A ++ C ++RP +++ +E L S Sbjct: 554 RDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCVKKVKEERPLFPQILSSIELLQHS 612
>Q07407:FGFR1_DROME Fibroblast growth factor receptor homolog 1 precursor - Drosophila| melanogaster (Fruit fly) Length = 729 Score = 122 bits (305), Expect = 8e-27 Identities = 90/314 (28%), Positives = 139/314 (44%), Gaps = 21/314 (6%) Frame = +1 Query: 859 ADWEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFATEAETTALRTSFK 1038 ++WE+ + L + + +G +G V + VAVK++ G T+ + +L Sbjct: 407 SNWELPRSHLVLGATLGEGAFGRVVMAEVNNAIVAVKMVKEGH----TDDDIASL----- 457 Query: 1039 QEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQY 1218 + V K +G + +L + NG V+VEY G LK + Sbjct: 458 --------VREMEVMKIIGRHINIINLLGCCSQNGP--------LYVIVEYAPHGNLKDF 501 Query: 1219 LIKNR------------------RRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTEN 1344 L KNR + K +++ A ++RG+ YL SR+ +HRD+ N Sbjct: 502 LYKNRPFGRDQDRDSSQPPPSPPAHVITEKDLIKFAHQIARGMDYLASRRCIHRDLAARN 561 Query: 1345 MLLDTQRNLKIADFGVARVEAQNPKDMTGATGTL--GYMAPEVLDGKPYNRKCDVYSFGI 1518 +L+ LKIADFG+AR G L +MAPE L K Y+ K DV+S+GI Sbjct: 562 VLVSDDYVLKIADFGLARDIQSTDYYRKNTNGRLPIKWMAPESLQEKFYDSKSDVWSYGI 621 Query: 1519 CLWEVYCC-DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDM 1695 LWE+ PYP + A+ + R + P C +MR+CW N D RP Sbjct: 622 LLWEIMTYGQQPYPTIMSAEELYTYLMSGQRMEKPAKCSMNIYILMRQCWHFNADDRPPF 681 Query: 1696 DEVVQLMEALDTSK 1737 E+V+ M+ L +K Sbjct: 682 TEIVEYMDKLLQTK 695
>Q07E01:MET_ORNAN Hepatocyte growth factor receptor precursor - Ornithorhynchus| anatinus (Duckbill platypus) Length = 1382 Score = 121 bits (304), Expect = 1e-26 Identities = 105/371 (28%), Positives = 165/371 (44%), Gaps = 26/371 (7%) Frame = +1 Query: 673 PRAKMASSAG-----DLPEVKFKRTGSLGSSDYVRADKIDLTSLDIQLEQQLNKKWSKSN 837 P A+M S+ PE +F + GS DL+ + + + +SN Sbjct: 992 PTAEMVSNESVDYRATFPEDQFPNSSQNGSCRQAHYPLADLSPILSSGDSNPSSPLLQSN 1051 Query: 838 ----IKSLGPKADWEI-------DLAKLEIRHVIAQGTYGTVYRGTY---DGQQV--AVK 969 I +L P + D + +I +G +G VY GT D +++ AVK Sbjct: 1052 VHIDISALNPDLVQAVQHVVIGPDSLMVHFTEIIGRGHFGCVYHGTLLDNDDKKIHCAVK 1111 Query: 970 LLDWGEDGFATEAETTALRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGAR 1149 L+ T+ E + F E + SHPNV +G + R Sbjct: 1112 SLNR-----ITDIEEVS---QFLTEGIIMKDFSHPNVLSLLGICL-------------RR 1150 Query: 1150 ANLPARACCVVVEYLAGGTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRD 1329 P VV+ Y+ G L+ + I+N K ++ L +++G+ YL S+K VHRD Sbjct: 1151 EGSPL----VVLPYMKHGDLRNF-IRNESHNPTVKDLIGFGLQVAKGMKYLASKKFVHRD 1205 Query: 1330 VKTENMLLDTQRNLKIADFGVAR----VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKC 1497 + N +LD + +K+ADFG+AR E + + TGA + +MA E L + + K Sbjct: 1206 LAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTSKS 1265 Query: 1498 DVYSFGICLWEVYCCDM-PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGN 1674 DV+SFG+ LWE+ PYPD++ D++ ++ Q R P CP +M KCW N Sbjct: 1266 DVWSFGVLLWELMTRGAPPYPDVNTFDITVYLL-QGRRLLQPEYCPDPLFEVMLKCWHPN 1324 Query: 1675 PDKRPDMDEVV 1707 + RP E+V Sbjct: 1325 AEMRPSFSELV 1335
>Q07E24:MET_MUSPF Hepatocyte growth factor receptor precursor - Mustela putorius furo| (European domestic ferret) (Mustela furo) Length = 1382 Score = 121 bits (304), Expect = 1e-26 Identities = 100/360 (27%), Positives = 161/360 (44%), Gaps = 21/360 (5%) Frame = +1 Query: 709 PEVKFKRTGSLGSSDYVRADKIDL----TSLDIQLEQQLNKKWSKSNIKSLGPKADWEID 876 PE +F + GS V+ DL TS D + L + ++ +L P+ + Sbjct: 1009 PEDQFPNSSQNGSCRQVQYPLTDLSPMLTSGDSDISSPLLQNTVHIDLSALNPELVQAVQ 1068 Query: 877 LAKL-------EIRHVIAQGTYGTVYRGTY---DGQQV--AVKLLDWGEDGFATEAETTA 1020 + VI +G +G VY GT D +++ AVK L+ D Sbjct: 1069 HVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDDKKIHCAVKSLNRITD--------IG 1120 Query: 1021 LRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAG 1200 + F E + SHPNV +G + + + VV+ Y+ Sbjct: 1121 EVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPL-----------------VVLPYMKH 1163 Query: 1201 GTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIA 1380 G L+ + I+N K ++ L +++G+ YL S+K VHRD+ N +LD + +K+A Sbjct: 1164 GDLRNF-IRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVA 1222 Query: 1381 DFGVAR----VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDM 1548 DFG+AR E + + TGA + +MA E L + + K DV+SFG+ LWE+ Sbjct: 1223 DFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGA 1282 Query: 1549 -PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 PYPD++ D++ ++ Q R P CP +M KCW + RP E+V + A+ Sbjct: 1283 PPYPDVNTFDITVYLL-QGRRLLQPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRISAI 1341
>Q2QLA9:MET_HORSE Hepatocyte growth factor receptor precursor - Equus caballus (Horse)| Length = 1381 Score = 121 bits (304), Expect = 1e-26 Identities = 100/360 (27%), Positives = 161/360 (44%), Gaps = 21/360 (5%) Frame = +1 Query: 709 PEVKFKRTGSLGSSDYVRADKIDL----TSLDIQLEQQLNKKWSKSNIKSLGPKADWEID 876 PE +F + GS V+ DL TS D + L + ++ +L P+ + Sbjct: 1008 PEDQFPNSSQNGSCRQVQYPLTDLSPILTSGDSDISSPLLQNTVHIDLSALNPELVQAVQ 1067 Query: 877 LAKL-------EIRHVIAQGTYGTVYRGTY---DGQQV--AVKLLDWGEDGFATEAETTA 1020 + VI +G +G VY GT D +++ AVK L+ D Sbjct: 1068 HVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDDKKIHCAVKSLNRITD--------IG 1119 Query: 1021 LRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAG 1200 + F E + SHPNV +G + + + VV+ Y+ Sbjct: 1120 EVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPL-----------------VVLPYMKH 1162 Query: 1201 GTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIA 1380 G L+ + I+N K ++ L +++G+ YL S+K VHRD+ N +LD + +K+A Sbjct: 1163 GDLRNF-IRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVA 1221 Query: 1381 DFGVAR----VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDM 1548 DFG+AR E + + TGA + +MA E L + + K DV+SFG+ LWE+ Sbjct: 1222 DFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGA 1281 Query: 1549 -PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 PYPD++ D++ ++ Q R P CP +M KCW + RP E+V + A+ Sbjct: 1282 PPYPDVNTFDITVYLL-QGRRLLQPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRISAI 1340
>Q75ZY9:MET_CANFA Hepatocyte growth factor receptor precursor - Canis familiaris (Dog)| Length = 1382 Score = 121 bits (304), Expect = 1e-26 Identities = 100/360 (27%), Positives = 161/360 (44%), Gaps = 21/360 (5%) Frame = +1 Query: 709 PEVKFKRTGSLGSSDYVRADKIDL----TSLDIQLEQQLNKKWSKSNIKSLGPKADWEID 876 PE +F + GS V+ DL TS D + L + ++ +L P+ + Sbjct: 1009 PEDQFPNSSQNGSCRQVQYPLTDLSPMLTSGDSDISSPLLQNTVHIDLSALNPELVQAVQ 1068 Query: 877 LAKL-------EIRHVIAQGTYGTVYRGTY---DGQQV--AVKLLDWGEDGFATEAETTA 1020 + VI +G +G VY GT D +++ AVK L+ D Sbjct: 1069 HVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDDKKIHCAVKSLNRITD--------IG 1120 Query: 1021 LRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAG 1200 + F E + SHPNV +G + + + VV+ Y+ Sbjct: 1121 EVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPL-----------------VVLPYMKH 1163 Query: 1201 GTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIA 1380 G L+ + I+N K ++ L +++G+ YL S+K VHRD+ N +LD + +K+A Sbjct: 1164 GDLRNF-IRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVA 1222 Query: 1381 DFGVAR----VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDM 1548 DFG+AR E + + TGA + +MA E L + + K DV+SFG+ LWE+ Sbjct: 1223 DFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGA 1282 Query: 1549 -PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 PYPD++ D++ ++ Q R P CP +M KCW + RP E+V + A+ Sbjct: 1283 PPYPDVNTFDITVYLL-QGRRLLQPEYCPDPLYEVMLKCWHPRAELRPSFSELVSRISAI 1341
>P00542:FES_FSVGA Tyrosine-protein kinase transforming protein Fes - Feline sarcoma| virus (strain Gardner-Arnstein) (Ga-FeSV) (Gardner-Arnstein feline leukemia oncovirus B) Length = 609 Score = 121 bits (304), Expect = 1e-26 Identities = 89/316 (28%), Positives = 145/316 (45%), Gaps = 5/316 (1%) Frame = +1 Query: 793 IQLEQQLNKKWSKSNIKSLGPKADWEIDLAKLEIRHVIAQGTYGTVYRGTY--DGQQVAV 966 ++ +Q L KK S + PK W ++ L + I +G +G V+ G D VAV Sbjct: 318 LRSQQPLTKK-SGIVLNRAVPKDKWVLNHEDLVLGEQIGRGNFGEVFSGRLRADNTLVAV 376 Query: 967 KLLDWGEDGFATEAETTALRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGA 1146 K E ++ F QE + + SHPN+ + +G K P+ Sbjct: 377 KS--------CRETLPPDIKAKFLQEAKILKQYSHPNIVRLIGVCTQ----KQPIY---- 420 Query: 1147 RANLPARACCVVVEYLAGGTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHR 1326 +V+E + GG +L + +L K ++Q+ D + G+ YL S+ +HR Sbjct: 421 ----------IVMELVQGGDFLTFL-RTEGARLRMKTLLQMVGDAAAGMEYLESKCCIHR 469 Query: 1327 DVKTENMLLDTQRNLKIADFGVARVEAQNPKDMTGATG--TLGYMAPEVLDGKPYNRKCD 1500 D+ N L+ + LKI+DFG++R A +G + + APE L+ Y+ + D Sbjct: 470 DLAARNCLVTEKNVLKISDFGMSREAADGIYAASGGLRQVPVKWTAPEALNYGRYSSESD 529 Query: 1501 VYSFGICLWEVYCCD-MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNP 1677 V+SFGI LWE + PYP+LS + V + R P CP A +M +CW P Sbjct: 530 VWSFGILLWETFSLGASPYPNLS-NQQTREFVEKGGRLPCPELCPDAVFRLMEQCWAYEP 588 Query: 1678 DKRPDMDEVVQLMEAL 1725 +RP + Q ++++ Sbjct: 589 GQRPSFSAIYQELQSI 604
>P08630:BTKL_DROME Tyrosine-protein kinase Btk29A - Drosophila melanogaster (Fruit fly)| Length = 786 Score = 121 bits (304), Expect = 1e-26 Identities = 78/295 (26%), Positives = 140/295 (47%), Gaps = 8/295 (2%) Frame = +1 Query: 865 WEIDLAKLEIRHVIAQGTYGTVYRGTYDGQ-QVAVKLLDWGEDGFATEAETTALRTSFKQ 1041 WEI +L + + G +G V RG + G AVK++ G T F + Sbjct: 519 WEIHPMELMLMEELGSGQFGVVRRGKWRGSIDTAVKMMKEG----------TMSEDDFIE 568 Query: 1042 EVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYL 1221 E V KL HPN+ + G R +V EY+ G+L YL Sbjct: 569 EAKVMTKLQHPNLVQLYGVCS------------------KHRPIYIVTEYMKHGSLLNYL 610 Query: 1222 IKNRRRKLAYK-VVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGVAR 1398 ++ + + +++ + + +S+G++YL +HRD+ N L+ ++ +K+ADFG+AR Sbjct: 611 RRHEKTLIGNMGLLLDMCIQVSKGMTYLERHNYIHRDLAARNCLVGSENVVKVADFGLAR 670 Query: 1399 VEAQNPKDMTGATG-TLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCC-DMPYPDLSFA 1572 + +G T + + PEVL+ ++ K DV+++G+ +WE++ C MPY L Sbjct: 671 YVLDDQYTSSGGTKFPIKWAPPEVLNYTRFSSKSDVWAYGVLMWEIFTCGKMPYGRLKNT 730 Query: 1573 DVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPD----MDEVVQLMEAL 1725 +V V + + + P+ C ++M+ CW P++RP MD++ + + L Sbjct: 731 EVVER-VQRGIILEKPKSCAKEIYDVMKLCWSHGPEERPAFRVLMDQLALVAQTL 784
>Q09YI9:MET_SHEEP Hepatocyte growth factor receptor precursor - Ovis aries (Sheep)| Length = 1384 Score = 121 bits (303), Expect = 1e-26 Identities = 100/360 (27%), Positives = 161/360 (44%), Gaps = 21/360 (5%) Frame = +1 Query: 709 PEVKFKRTGSLGSSDYVRADKIDL----TSLDIQLEQQLNKKWSKSNIKSLGPKADWEID 876 PE +F + GS V+ DL TS D + L + ++ +L P+ + Sbjct: 1009 PEDQFPNSSQNGSCRQVQYPLTDLSPILTSGDSDISSPLLQNTVHIDLSALNPELVQAVQ 1068 Query: 877 LAKL-------EIRHVIAQGTYGTVYRGTY---DGQQV--AVKLLDWGEDGFATEAETTA 1020 + VI +G +G VY GT D +++ AVK L+ D Sbjct: 1069 HVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDDKKIHCAVKSLNRITD--------IG 1120 Query: 1021 LRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAG 1200 + F E + SHPNV +G + + + VV+ Y+ Sbjct: 1121 EVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPL-----------------VVLPYMKH 1163 Query: 1201 GTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIA 1380 G L+ + I+N K ++ L +++G+ YL S+K VHRD+ N +LD + +K+A Sbjct: 1164 GDLRNF-IRNETHNPTVKDLIGFGLQVAKGMEYLASKKFVHRDLAARNCMLDEKFTVKVA 1222 Query: 1381 DFGVAR----VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDM 1548 DFG+AR E + + TGA + +MA E L + + K DV+SFG+ LWE+ Sbjct: 1223 DFGLARDVYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGA 1282 Query: 1549 -PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 PYPD++ D++ ++ Q R P CP +M KCW + RP E+V + A+ Sbjct: 1283 PPYPDVNTFDITVYLL-QGRRLLQPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRIAAI 1341
>Q00PJ8:MET_ATEAB Hepatocyte growth factor receptor precursor - Atelerix albiventris| (Middle-African hedgehog) Length = 1382 Score = 121 bits (303), Expect = 1e-26 Identities = 100/360 (27%), Positives = 160/360 (44%), Gaps = 21/360 (5%) Frame = +1 Query: 709 PEVKFKRTGSLGSSDYVRADKIDL----TSLDIQLEQQLNKKWSKSNIKSLGPKADWEID 876 PE +F + GS V+ DL TS D + L + ++ +L P+ + Sbjct: 1009 PEDQFPNSSQNGSCRQVQYPLTDLSPILTSGDSDISSPLLQNTVHIDLSALNPELVQAVQ 1068 Query: 877 LAKL-------EIRHVIAQGTYGTVYRGTY---DGQQV--AVKLLDWGEDGFATEAETTA 1020 + VI +G +G VY GT D +++ AVK L+ D Sbjct: 1069 HVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDDKKIHCAVKSLNRITD--------IG 1120 Query: 1021 LRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAG 1200 + F E + SHPNV +G + + + VV+ Y+ Sbjct: 1121 EVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPL-----------------VVLPYMKH 1163 Query: 1201 GTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIA 1380 G L+ + I+N K ++ L +++G+ YL S+K VHRD+ N +LD +K+A Sbjct: 1164 GDLRNF-IRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDENFTVKVA 1222 Query: 1381 DFGVAR----VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDM 1548 DFG+AR E + + TGA + +MA E L + + K DV+SFG+ LWE+ Sbjct: 1223 DFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGA 1282 Query: 1549 -PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 PYPD++ D++ ++ Q R P CP +M KCW + RP E+V + A+ Sbjct: 1283 PPYPDVNTFDITVYLL-QGRRLLQPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRISAI 1341
>P00532:RAF_MSV36 Serine/threonine-protein kinase-transforming protein raf - Murine| sarcoma virus 3611 Length = 323 Score = 120 bits (302), Expect = 2e-26 Identities = 84/299 (28%), Positives = 154/299 (51%), Gaps = 9/299 (3%) Frame = +1 Query: 865 WEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFATEAETTALRTSFKQE 1044 W+++ +++ + I G++GTVY+G + G VAVK+L + T +F+ E Sbjct: 17 WKMEASEVMLSTRIGSGSFGTVYKGKWHGD-VAVKILKVVDP-------TPEQLQAFRNE 68 Query: 1045 VAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYLI 1224 VAV K H N+ F+G DN A +V ++ G +L ++L Sbjct: 69 VAVLRKTRHVNILLFMGYM---------TKDNLA----------IVTQWCEGSSLYKHLH 109 Query: 1225 KNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGVARVE 1404 + ++++ +A ++G+ YLH++ I+HRD+K+ N+ L +KI DFG+A V+ Sbjct: 110 VQETKFQMFQLI-DIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGLATVK 168 Query: 1405 AQ--NPKDMTGATGTLGYMAPEVL---DGKPYNRKCDVYSFGICLWEVYCCDMPYPDLSF 1569 ++ + + TG++ +MAPEV+ D P++ + DVYS+GI L+E+ ++PY ++ Sbjct: 169 SRWSGSQQVEQPTGSVLWMAPEVIRMQDDNPFSFQSDVYSYGIVLYELMAGELPYAHINN 228 Query: 1570 ADVSSAVVHQN-LRPDIPRC---CPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDTS 1734 D +V + PD+ R CP A ++ C ++RP +++ +E L S Sbjct: 229 RDQIIFMVGRGYASPDLSRLYKNCPKAIKRLVADCVKKVKEERPLFPQILSSIELLQHS 287
>Q07E37:MET_NEONE Hepatocyte growth factor receptor precursor - Neofelis nebulosa| (Clouded leopard) Length = 1382 Score = 120 bits (301), Expect = 2e-26 Identities = 98/360 (27%), Positives = 161/360 (44%), Gaps = 21/360 (5%) Frame = +1 Query: 709 PEVKFKRTGSLGSSDYVRADKIDLTSL----DIQLEQQLNKKWSKSNIKSLGPKADWEID 876 PE +F + GS V+ DL+ + D + L + ++ +L P+ + Sbjct: 1009 PEDQFPNSSQNGSCRQVQYPLTDLSPMLNSGDSDISSPLLQNTVHIDLSALNPELVQAVQ 1068 Query: 877 LAKL-------EIRHVIAQGTYGTVYRGTY---DGQQV--AVKLLDWGEDGFATEAETTA 1020 + VI +G +G VY GT D +++ AVK L+ D Sbjct: 1069 HVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDSDDKKIHCAVKSLNRITD--------IG 1120 Query: 1021 LRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAG 1200 + F E + SHPNV +G + + + VV+ Y+ Sbjct: 1121 EVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPL-----------------VVLPYMKH 1163 Query: 1201 GTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIA 1380 G L+ + I+N K ++ L +++G+ YL S+K VHRD+ N +LD + +K+A Sbjct: 1164 GDLRNF-IRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVA 1222 Query: 1381 DFGVAR----VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDM 1548 DFG+AR E + + TGA + +MA E L + + K DV+SFG+ LWE+ Sbjct: 1223 DFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGA 1282 Query: 1549 -PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 PYPD++ D++ ++ Q R P CP +M KCW + RP E+V + A+ Sbjct: 1283 PPYPDVNTFDITVYLL-QGRRLLQPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRISAI 1341
>A0M8S8:MET_FELCA Hepatocyte growth factor receptor precursor - Felis silvestris catus| (Cat) Length = 1382 Score = 120 bits (301), Expect = 2e-26 Identities = 98/360 (27%), Positives = 161/360 (44%), Gaps = 21/360 (5%) Frame = +1 Query: 709 PEVKFKRTGSLGSSDYVRADKIDLTSL----DIQLEQQLNKKWSKSNIKSLGPKADWEID 876 PE +F + GS V+ DL+ + D + L + ++ +L P+ + Sbjct: 1009 PEDQFPNSSQNGSCRQVQYPLTDLSPMLNSGDSDISSPLLQNTVHIDLSALNPELVQAVQ 1068 Query: 877 LAKL-------EIRHVIAQGTYGTVYRGTY---DGQQV--AVKLLDWGEDGFATEAETTA 1020 + VI +G +G VY GT D +++ AVK L+ D Sbjct: 1069 HVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDSDDKKIHCAVKSLNRITD--------IG 1120 Query: 1021 LRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAG 1200 + F E + SHPNV +G + + + VV+ Y+ Sbjct: 1121 EVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPL-----------------VVLPYMKH 1163 Query: 1201 GTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIA 1380 G L+ + I+N K ++ L +++G+ YL S+K VHRD+ N +LD + +K+A Sbjct: 1164 GDLRNF-IRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVA 1222 Query: 1381 DFGVAR----VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDM 1548 DFG+AR E + + TGA + +MA E L + + K DV+SFG+ LWE+ Sbjct: 1223 DFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGA 1282 Query: 1549 -PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 PYPD++ D++ ++ Q R P CP +M KCW + RP E+V + A+ Sbjct: 1283 PPYPDVNTFDITVYLL-QGRRLLQPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRISAI 1341
>A1X150:MET_ECHTE Hepatocyte growth factor receptor precursor - Echinops telfairi| (Lesser hedgehog tenrec) Length = 1380 Score = 120 bits (301), Expect = 2e-26 Identities = 100/360 (27%), Positives = 161/360 (44%), Gaps = 21/360 (5%) Frame = +1 Query: 709 PEVKFKRTGSLGSSDYVRADKIDL----TSLDIQLEQQLNKKWSKSNIKSLGPKADWEID 876 PE +F + GS V+ DL TS D + L + ++ +L P+ + Sbjct: 1007 PEDQFPNSSQNGSCRQVQYPLPDLSPILTSGDSDISSPLLQNTVHIDLSALNPELVQAVQ 1066 Query: 877 LAKL-------EIRHVIAQGTYGTVYRGTY---DGQQV--AVKLLDWGEDGFATEAETTA 1020 + VI +G +G VY GT D +++ AVK L+ D Sbjct: 1067 HVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDDRKIHCAVKSLNRITD--------IG 1118 Query: 1021 LRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAG 1200 + F E + SHPNV +G + + + VV+ Y+ Sbjct: 1119 EVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPL-----------------VVLPYMKH 1161 Query: 1201 GTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIA 1380 G L+ + I+N K ++ L +++G+ YL S+K VHRD+ N +LD + +K+A Sbjct: 1162 GDLRNF-IRNETHSPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDGKFTVKVA 1220 Query: 1381 DFGVAR----VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDM 1548 DFG+AR E + + TGA + +MA E L + + K DV+SFG+ LWE+ Sbjct: 1221 DFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGA 1280 Query: 1549 -PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 PYPD++ D++ ++ Q R P CP +M KCW + RP E+V + A+ Sbjct: 1281 PPYPDVNTFDITVYLL-QGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFTELVSRISAI 1339
>Q108U6:MET_LOXAF Hepatocyte growth factor receptor precursor - Loxodonta africana| (African elephant) Length = 1382 Score = 119 bits (299), Expect = 4e-26 Identities = 85/291 (29%), Positives = 134/291 (46%), Gaps = 11/291 (3%) Frame = +1 Query: 886 LEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFATEAETTALRTS------FKQEV 1047 + VI +G +G VY GT LLD G+ ++ T F E Sbjct: 1079 VHFNEVIGRGHFGCVYHGT---------LLDNGDKKIHCAVKSLNRITDIGEVSQFLTEG 1129 Query: 1048 AVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYLIK 1227 + SHPNV +G + + + VV+ Y+ G L+ + I+ Sbjct: 1130 IIMKDFSHPNVLSLLGICLRSEGSPL-----------------VVLPYMKHGDLRNF-IR 1171 Query: 1228 NRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGVAR--- 1398 N K ++ L +++G+ YL S+K VHRD+ N +LD + +K+ADFG+AR Sbjct: 1172 NETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDVY 1231 Query: 1399 -VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDM-PYPDLSFA 1572 E + + TGA + +MA E L + + K DV+SFG+ LWE+ PYPD++ Sbjct: 1232 DKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTF 1291 Query: 1573 DVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 D++ ++ Q R P CP +M KCW + RP E+V + A+ Sbjct: 1292 DITVYLL-QGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAI 1341
>Q769I5:MET_BOVIN Hepatocyte growth factor receptor precursor - Bos taurus (Bovine)| Length = 1384 Score = 119 bits (299), Expect = 4e-26 Identities = 99/360 (27%), Positives = 159/360 (44%), Gaps = 21/360 (5%) Frame = +1 Query: 709 PEVKFKRTGSLGSSDYVRADKIDL----TSLDIQLEQQLNKKWSKSNIKSLGPKADWEID 876 PE +F GS V+ DL TS D + L + ++ +L P+ + Sbjct: 1009 PEDQFPNASQNGSCRQVQYPLTDLSPILTSGDSDISSPLLQNTIHIDLSALNPELVQAVQ 1068 Query: 877 LAKL-------EIRHVIAQGTYGTVYRGTY---DGQQV--AVKLLDWGEDGFATEAETTA 1020 + VI +G +G VY GT D +++ AVK L+ D Sbjct: 1069 HVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDDKKIHCAVKSLNRITD--------IG 1120 Query: 1021 LRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAG 1200 + F E + SHPNV +G + + + VV+ Y+ Sbjct: 1121 EVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPL-----------------VVLPYMKH 1163 Query: 1201 GTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIA 1380 G L+ + I+N K ++ L +++G+ YL S+K VHRD+ N +LD + +K+A Sbjct: 1164 GDLRNF-IRNETHNPTVKDLIGFGLQVAKGMEYLASKKFVHRDLAARNCMLDEKFTVKVA 1222 Query: 1381 DFGVAR----VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDM 1548 DFG+AR E + + TGA + +MA E L + + K DV+SFG+ LWE+ Sbjct: 1223 DFGLARDVYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGA 1282 Query: 1549 -PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 PYPD++ D++ ++ Q R P CP +M KCW + RP E+V + + Sbjct: 1283 PPYPDVNTFDITVYLL-QGRRLLQPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRISVI 1341
>P00531:MIL_AVIMH Serine/threonine-protein kinase-transforming protein mil - Avian| retrovirus MH2 Length = 380 Score = 119 bits (298), Expect = 5e-26 Identities = 84/299 (28%), Positives = 153/299 (51%), Gaps = 9/299 (3%) Frame = +1 Query: 865 WEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFATEAETTALRTSFKQE 1044 WEI+ +++ + I G++GTVY+G + G VAVK+L + T +F+ E Sbjct: 75 WEIEASEVLLSTRIGSGSFGTVYKGKWHGD-VAVKILKVVDP-------TPEQFQAFRNE 126 Query: 1045 VAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYLI 1224 VAV K H N+ F+G DN A +V ++ G +L ++L Sbjct: 127 VAVLRKTRHVNILLFMGYM---------TKDNLA----------IVTQWCEGSSLYKHLH 167 Query: 1225 KNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGVARVE 1404 + ++++ +A ++G+ YLH++ I+HRD+K+ N+ L +KI DFG+A V+ Sbjct: 168 VQETKFQMFQLI-DIARQTAQGMDYLHAKNIIHRDMKSNNIFLHGGLTVKIGDFGLATVK 226 Query: 1405 AQ--NPKDMTGATGTLGYMAPEVL---DGKPYNRKCDVYSFGICLWEVYCCDMPYPDLSF 1569 ++ + + TG++ +MAPEV+ D P++ + DVYS+GI L+E+ ++PY ++ Sbjct: 227 SRWSGSQQVEQPTGSILWMAPEVIRMQDSNPFSFQSDVYSYGIVLYELMTGELPYSHINN 286 Query: 1570 ADVSSAVVHQN-LRPDIPRC---CPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDTS 1734 D +V + PD+ + CP A ++ C ++RP +++ + L S Sbjct: 287 RDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCLKKVREERPLFPQILSSIALLQHS 345
>P97504:BMX_MOUSE Cytoplasmic tyrosine-protein kinase BMX - Mus musculus (Mouse)| Length = 651 Score = 119 bits (298), Expect = 5e-26 Identities = 84/289 (29%), Positives = 133/289 (46%), Gaps = 2/289 (0%) Frame = +1 Query: 865 WEIDLAKLEIRHVIAQGTYGTVYRGTYDGQ-QVAVKLLDWGEDGFATEAETTALRTSFKQ 1041 WE+ ++ + + G +G V G + GQ VAVK++ ++G +E E F Q Sbjct: 386 WELKREEITLLKELGNGQFGVVQLGQWKGQYDVAVKMI---KEGAMSEDE-------FFQ 435 Query: 1042 EVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYL 1221 E KLSHP + KF G K P+ +V EY+ G L YL Sbjct: 436 EAQTMMKLSHPKLVKFYGVC----SKKYPIY--------------IVTEYITNGCLLNYL 477 Query: 1222 IKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGVAR- 1398 K+ + L ++++ D+ G+++L S + +HRD+ N L+D+ ++K++DFG+ R Sbjct: 478 -KSHGKGLESCQLLEMCYDVCEGMAFLESHQFIHRDLAARNCLVDSDLSVKVSDFGMTRY 536 Query: 1399 VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDMPYPDLSFADV 1578 V G + + APEV Y+ K DV++FGI +WEV+ DL Sbjct: 537 VLDDQYVSSVGTKFPVKWSAPEVFHYFKYSSKSDVWAFGILMWEVFSLGKQPYDLYDNSE 596 Query: 1579 SSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 V Q R P+ IM CW P+KRP +++ +E L Sbjct: 597 VVVKVSQGHRLYRPQLASDTIYQIMYSCWHELPEKRPTFQQLLSAIEPL 645
>P00530:FPS_FUJSV Tyrosine-protein kinase transforming protein FPS - Fujinami sarcoma| virus Length = 873 Score = 119 bits (297), Expect = 7e-26 Identities = 82/295 (27%), Positives = 140/295 (47%), Gaps = 5/295 (1%) Frame = +1 Query: 856 KADWEIDLAKLEIRHVIAQGTYGTVYRGTY--DGQQVAVKLLDWGEDGFATEAETTALRT 1029 K W ++ + + I +G +G V+ G D VAVK E L+ Sbjct: 602 KDKWVLNHEDVLLGERIGRGNFGEVFSGRLRADNTPVAVKS--------CRETLPPELKA 653 Query: 1030 SFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTL 1209 F QE + + +HPN+ + +G K P+ +V+E + GG Sbjct: 654 KFLQEARILKQCNHPNIVRLIGVCTQ----KQPIY--------------IVMELVQGGDF 695 Query: 1210 KQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFG 1389 +L +++ +L K ++++ + + G+ YL S+ +HRD+ N L+ + LKI+DFG Sbjct: 696 LSFL-RSKGPRLKMKKLIKMMENAAAGMEYLESKHCIHRDLAARNCLVTEKNTLKISDFG 754 Query: 1390 VARVEAQNPKDMTGATGTL--GYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCD-MPYPD 1560 ++R E TG + + APE L+ Y+ + DV+SFGI LWE + +PY + Sbjct: 755 MSRQEEDGVYASTGGMKQIPVKWTAPEALNYGWYSSESDVWSFGILLWEAFSLGAVPYAN 814 Query: 1561 LSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 LS A + Q +R + P CP +M++CW+ +P +RP V Q + A+ Sbjct: 815 LSNQQTREA-IEQGVRLEPPEQCPEDVYRLMQRCWEYDPHRRPSFGAVHQDLIAI 868
>P00541:FPS_AVISP Tyrosine-protein kinase transforming protein Fps - Avian sarcoma| virus (strain PRCII) Length = 533 Score = 118 bits (295), Expect = 1e-25 Identities = 82/295 (27%), Positives = 139/295 (47%), Gaps = 5/295 (1%) Frame = +1 Query: 856 KADWEIDLAKLEIRHVIAQGTYGTVYRGTY--DGQQVAVKLLDWGEDGFATEAETTALRT 1029 K W ++ + + I +G +G V+ G D VAVK E L+ Sbjct: 262 KDKWVLNHEDVLLGERIGRGNFGEVFSGRLRADNTPVAVKS--------CRETLPPELKA 313 Query: 1030 SFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTL 1209 F QE + + +HPN+ + +G K P+ +V+E + GG Sbjct: 314 KFLQEARILKQYNHPNIVRLIGVCTQ----KQPIY--------------IVMELVQGGDF 355 Query: 1210 KQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFG 1389 +L +++ L K ++++ + + G+ YL S+ +HRD+ N L+ + LKI+DFG Sbjct: 356 LSFL-RSKGPHLKMKELIKMMENAAAGMEYLESKHCIHRDLAARNCLVTEKNTLKISDFG 414 Query: 1390 VARVEAQNPKDMTGATGTL--GYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCD-MPYPD 1560 ++R E TG + + APE L+ Y+ + DV+SFGI LWE + +PY + Sbjct: 415 MSRQEEDGVYASTGGMKQIPVKWTAPEALNYGRYSSESDVWSFGILLWEAFSLGAVPYAN 474 Query: 1561 LSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 LS A + Q +R + P CP +M++CW+ +P +RP V Q + A+ Sbjct: 475 LSNQQTREA-IEQGVRLEPPEQCPEDVYRLMQRCWEYDPRRRPSFGAVHQDLIAI 528
>P09560:RAF1_XENLA RAF proto-oncogene serine/threonine-protein kinase - Xenopus laevis| (African clawed frog) Length = 638 Score = 117 bits (294), Expect = 2e-25 Identities = 90/314 (28%), Positives = 156/314 (49%), Gaps = 12/314 (3%) Frame = +1 Query: 829 KSNIKSLGPKAD---WEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFA 999 K+ I++ G + WEI +++ + I G++GTVY+G + G VAVK+L Sbjct: 318 KNKIRARGQRDSSYYWEIIASEVMLSSRIGSGSFGTVYKGKWHGD-VAVKILK------V 370 Query: 1000 TEAETTALRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCV 1179 T+ L+ +F+ EVAV K H N+ F+G DN A + Sbjct: 371 TDPTPEQLQ-AFRNEVAVLRKTRHVNILLFMGYM---------TKDNLA----------I 410 Query: 1180 VVEYLAGGTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDT 1359 V ++ G +L Y + K ++ +A ++G+ YLH++ I+HRD+K+ N+ L Sbjct: 411 VTQWCEGSSL-YYHLHVLDTKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHE 469 Query: 1360 QRNLKIADFGVARVEAQ--NPKDMTGATGTLGYMAPEVL---DGKPYNRKCDVYSFGICL 1524 +KI DFG+A V+ + + + TG++ +MAPEV+ D P++ + DVYS+GI L Sbjct: 470 GLTVKIGDFGLATVKTRWSGSQQVEQLTGSILWMAPEVIRMQDNNPFSFQSDVYSYGIVL 529 Query: 1525 WEVYCCDMPYPDLSFAD-VSSAVVHQNLRPDIPRC---CPSAFANIMRKCWDGNPDKRPD 1692 +E+ ++PY + D + V + PD+ + CP A ++ D+RP Sbjct: 530 YELMTGELPYSHIRDRDQIIFLVGRGGVVPDLSKLYKNCPKAMKRLVADSIKKLRDERPL 589 Query: 1693 MDEVVQLMEALDTS 1734 +++ +E L S Sbjct: 590 FPQILSSIELLQHS 603
>P53668:LIMK1_MOUSE LIM domain kinase 1 - Mus musculus (Mouse)| Length = 647 Score = 117 bits (293), Expect = 2e-25 Identities = 90/292 (30%), Positives = 138/292 (47%), Gaps = 17/292 (5%) Frame = +1 Query: 901 VIAQGTYGTVYRGTY--DGQQVAVKLLDWGEDGFATEAETTALRTSFKQEVAVWHKLSHP 1074 V+ +G +G + T+ G+ + +K L F E + T F +EV V L HP Sbjct: 344 VLGKGCFGQAIKVTHRETGEVMVMKELI----RFDEETQRT-----FLKEVKVMRCLEHP 394 Query: 1075 NVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYLIKNRRRKLAYK 1254 NV KF+G L + EY+ GGTL+ +IKN + + Sbjct: 395 NVLKFIGVLYKDKRLNF------------------ITEYIKGGTLRG-IIKNMDSQYPWS 435 Query: 1255 VVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGVARV---EAQNPKDM 1425 V A D++ G++YLHS I+HRD+ + N L+ RN+ +ADFG+AR+ E +D+ Sbjct: 436 QRVSFAKDIASGMAYLHSMNIIHRDLNSHNCLVRENRNVVVADFGLARLMIDEKNQSEDL 495 Query: 1426 TG-----------ATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDMPYPDLSFA 1572 G +MAPE+++G+ Y+ K DV+SFGI L E+ PD Sbjct: 496 RSLKKPDRKKRYTVVGNPYWMAPEMINGRSYDEKVDVFSFGIVLCEIIGRVNADPDYLPR 555 Query: 1573 DVSSAV-VHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 + + V L P CP +F I +C D +P+KRP ++ Q +E L Sbjct: 556 TMDFGLNVRGFLDRYCPPNCPPSFFPITVRCCDLDPEKRPSFVKLEQWLETL 607
>P12965:MOS_XENLA Serine/threonine-protein kinase mos - Xenopus laevis (African clawed| frog) Length = 359 Score = 117 bits (292), Expect = 3e-25 Identities = 91/309 (29%), Positives = 146/309 (47%), Gaps = 18/309 (5%) Frame = +1 Query: 847 LGPKADW-EIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFATEAETTAL 1023 L P+ W ID ++ + + G +G+VYR TY G+ VA+K + + + A Sbjct: 49 LPPRLAWCSIDWEQVLLLEPLGSGGFGSVYRATYRGETVALKKVK------RSTKNSLAS 102 Query: 1024 RTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACC---VVVEYL 1194 R SF E+ +L HP+V + V AS A+ P C +++EY Sbjct: 103 RQSFWAELNA-ARLRHPHVVRVVAAS----------------ASCPGDPGCPGTIIMEYT 145 Query: 1195 AGGTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLK 1374 GTL Q I R L ++ ++ A ++ GL +LH +VH D+K N+LL K Sbjct: 146 GTGTLHQR-IYGRSPPLGAEICMRYARHVADGLRFLHRDGVVHLDLKPANVLLAPGDLCK 204 Query: 1375 IADFGVARVEAQNPKDMTGAT---------GTLGYMAPEVLDGKPYNRKCDVYSFGICLW 1527 I DFG ++ + + G GT + APE+L G+P K D+YSF I LW Sbjct: 205 IGDFGCSQRLREGDEAAGGEPCCTQLRHVGGTYTHRAPELLKGEPVTAKADIYSFAITLW 264 Query: 1528 EVYCCDMPYPDLSFADVSSAVVHQNLRPDIPRCCP-----SAFANIMRKCWDGNPDKRPD 1692 ++ ++PY V AVV +LRP++ A I++ CW P +RP+ Sbjct: 265 QMVSRELPYTG-DRQCVLYAVVAYDLRPEMGPLFSHTEEGRAARTIVQSCWAARPQERPN 323 Query: 1693 MDEVVQLME 1719 +++++ +E Sbjct: 324 AEQLLERLE 332
>P16879:FES_MOUSE Proto-oncogene tyrosine-protein kinase Fes/Fps - Mus musculus (Mouse)| Length = 820 Score = 117 bits (292), Expect = 3e-25 Identities = 88/315 (27%), Positives = 143/315 (45%), Gaps = 7/315 (2%) Frame = +1 Query: 802 EQQLNKKWSKSNIKSLGPKADWEIDLAKLEIRHVIAQGTYGTVYRGTY--DGQQVAVKLL 975 +Q L KK +++ PK W + L + I +G +G V+ G D VAVK Sbjct: 532 QQPLTKKSGVVLFRAV-PKDKWVLKHEDLVLGEQIGRGNFGEVFSGRLRADNTPVAVKS- 589 Query: 976 DWGEDGFATEAETTALRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARAN 1155 E L+ F QE + + +HPN+ + +G K P+ Sbjct: 590 -------CRETLPPDLKAKFLQEARILKQYNHPNIVRLIGVCTQ----KQPIY------- 631 Query: 1156 LPARACCVVVEYLAGGTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVK 1335 +V+E + GG +L + +L K ++Q+ D + G+ YL S+ +HRD+ Sbjct: 632 -------IVMELVQGGDFLTFL-RTEGARLRVKTLLQMMGDAAAGMEYLESKCCIHRDLA 683 Query: 1336 TENMLLDTQRNLKIADFGVARVEAQNPKDMTGATG----TLGYMAPEVLDGKPYNRKCDV 1503 N L+ + LKI+DFG++R EA +G + + APE L+ Y+ + DV Sbjct: 684 ARNCLVTEKNVLKISDFGMSREEADG--IYAACSGLRQVPVKWTAPEALNYGRYSSESDV 741 Query: 1504 YSFGICLWEVYCCD-MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPD 1680 +SFGI LWE + PYP+L+ + V + R P CP A +M +CW P Sbjct: 742 WSFGILLWETFSLGASPYPNLT-NQQTREFVEKGHRLPCPELCPDAVFRLMEQCWAYEPG 800 Query: 1681 KRPDMDEVVQLMEAL 1725 +RP + Q + ++ Sbjct: 801 QRPSFSIICQELHSI 815
>P14056:ARAF_RAT A-Raf proto-oncogene serine/threonine-protein kinase - Rattus| norvegicus (Rat) Length = 604 Score = 116 bits (290), Expect = 4e-25 Identities = 82/315 (26%), Positives = 155/315 (49%), Gaps = 13/315 (4%) Frame = +1 Query: 829 KSNIKSLGPKAD---WEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFA 999 K +K+LG + WE+ +++++ I G++GTV+RG + G VAVK+L + Sbjct: 286 KKKVKNLGYRDSGYYWEVPPSEVQLLKRIGTGSFGTVFRGRWHGD-VAVKVLKVAQP--- 341 Query: 1000 TEAETTALRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCV 1179 T +FK E+ V K H N+ F+G + + Sbjct: 342 ----TAEQAQAFKNEMQVLRKTRHVNILLFMGF-------------------MTRPGFAI 378 Query: 1180 VVEYLAGGTLKQYL-IKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLD 1356 + ++ G +L +L + + R + ++ +A ++G+ YLH++ I+HRD+K+ N+ L Sbjct: 379 ITQWCEGSSLYHHLHVADTRFDMVQ--LIDVARQTAQGMDYLHAKNIIHRDLKSNNIFLH 436 Query: 1357 TQRNLKIADFGVARVEAQ--NPKDMTGATGTLGYMAPEVL---DGKPYNRKCDVYSFGIC 1521 +KI DFG+A V+ + + + +G++ +MA EV+ D PY+ + DVY++G+ Sbjct: 437 EGLTVKIGDFGLATVKTRWSGAQPLEQPSGSVLWMAAEVIRMQDPNPYSFQSDVYAYGVV 496 Query: 1522 LWEVYCCDMPYPDLSFADVSSAVVHQN-LRPDIPRC---CPSAFANIMRKCWDGNPDKRP 1689 L+E+ +PY + D +V + L PD+ + CP A ++ C ++RP Sbjct: 497 LYELMTGSLPYSHIGSRDQIIFMVGRGYLSPDLSKIFSNCPKAMRRLLTDCLKFQREERP 556 Query: 1690 DMDEVVQLMEALDTS 1734 +++ +E L S Sbjct: 557 LFPQILATIELLQRS 571
>O19004:ARAF_PIG A-Raf proto-oncogene serine/threonine-protein kinase - Sus scrofa| (Pig) Length = 606 Score = 116 bits (290), Expect = 4e-25 Identities = 82/315 (26%), Positives = 155/315 (49%), Gaps = 13/315 (4%) Frame = +1 Query: 829 KSNIKSLGPKAD---WEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFA 999 K +K+LG + WE+ +++++ I G++GTV+RG + G VAVK+L + Sbjct: 288 KKKVKNLGYRDSGYYWEVPPSEVQLLKRIGTGSFGTVFRGRWHGD-VAVKVLKVAQP--- 343 Query: 1000 TEAETTALRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCV 1179 T +FK E+ V K H N+ F+G + + Sbjct: 344 ----TAEQAQAFKNEMQVLRKTRHVNILLFMGF-------------------MTRPGFAI 380 Query: 1180 VVEYLAGGTLKQYL-IKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLD 1356 + ++ G +L +L + + R + ++ +A ++G+ YLH++ I+HRD+K+ N+ L Sbjct: 381 ITQWCEGSSLYHHLHVADTRFDMVQ--LIDVARQTAQGMDYLHAKNIIHRDLKSNNIFLH 438 Query: 1357 TQRNLKIADFGVARVEAQ--NPKDMTGATGTLGYMAPEVL---DGKPYNRKCDVYSFGIC 1521 +KI DFG+A V+ + + + +G++ +MA EV+ D PY+ + DVY++G+ Sbjct: 439 EGLTVKIGDFGLATVKTRWSGAQPLEQPSGSVLWMAAEVIRMQDPNPYSFQSDVYAYGVV 498 Query: 1522 LWEVYCCDMPYPDLSFADVSSAVVHQN-LRPDIPRC---CPSAFANIMRKCWDGNPDKRP 1689 L+E+ +PY + D +V + L PD+ + CP A ++ C ++RP Sbjct: 499 LYELMTGSLPYSHIGSRDQIIFMVGRGYLSPDLSKISSNCPKAMRRLLSDCLKFQREERP 558 Query: 1690 DMDEVVQLMEALDTS 1734 +++ +E L S Sbjct: 559 LFPQILATIELLQRS 573
>P04627:ARAF_MOUSE A-Raf proto-oncogene serine/threonine-protein kinase - Mus musculus| (Mouse) Length = 604 Score = 116 bits (290), Expect = 4e-25 Identities = 82/315 (26%), Positives = 155/315 (49%), Gaps = 13/315 (4%) Frame = +1 Query: 829 KSNIKSLGPKAD---WEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFA 999 K +K+LG + WE+ +++++ I G++GTV+RG + G VAVK+L + Sbjct: 286 KKKVKNLGYRDSGYYWEVPPSEVQLLKRIGTGSFGTVFRGRWHGD-VAVKVLKVAQP--- 341 Query: 1000 TEAETTALRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCV 1179 T +FK E+ V K H N+ F+G + + Sbjct: 342 ----TAEQAQAFKNEMQVLRKTRHVNILLFMGF-------------------MTRPGFAI 378 Query: 1180 VVEYLAGGTLKQYL-IKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLD 1356 + ++ G +L +L + + R + ++ +A ++G+ YLH++ I+HRD+K+ N+ L Sbjct: 379 ITQWCEGSSLYHHLHVADTRFDMVQ--LIDVARQTAQGMDYLHAKNIIHRDLKSNNIFLH 436 Query: 1357 TQRNLKIADFGVARVEAQ--NPKDMTGATGTLGYMAPEVL---DGKPYNRKCDVYSFGIC 1521 +KI DFG+A V+ + + + +G++ +MA EV+ D PY+ + DVY++G+ Sbjct: 437 EGLTVKIGDFGLATVKTRWSGAQPLEQPSGSVLWMAAEVIRMQDPNPYSFQSDVYAYGVV 496 Query: 1522 LWEVYCCDMPYPDLSFADVSSAVVHQN-LRPDIPRC---CPSAFANIMRKCWDGNPDKRP 1689 L+E+ +PY + D +V + L PD+ + CP A ++ C ++RP Sbjct: 497 LYELMTGSLPYSHIGSRDQIIFMVGRGYLSPDLSKIFSNCPKAMRRLLTDCLKFQREERP 556 Query: 1690 DMDEVVQLMEALDTS 1734 +++ +E L S Sbjct: 557 LFPQILATIELLQRS 571
>P10398:ARAF_HUMAN A-Raf proto-oncogene serine/threonine-protein kinase - Homo sapiens| (Human) Length = 606 Score = 116 bits (290), Expect = 4e-25 Identities = 82/315 (26%), Positives = 155/315 (49%), Gaps = 13/315 (4%) Frame = +1 Query: 829 KSNIKSLGPKAD---WEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFA 999 K +K+LG + WE+ +++++ I G++GTV+RG + G VAVK+L + Sbjct: 288 KKKVKNLGYRDSGYYWEVPPSEVQLLKRIGTGSFGTVFRGRWHGD-VAVKVLKVSQP--- 343 Query: 1000 TEAETTALRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCV 1179 T +FK E+ V K H N+ F+G + + Sbjct: 344 ----TAEQAQAFKNEMQVLRKTRHVNILLFMGF-------------------MTRPGFAI 380 Query: 1180 VVEYLAGGTLKQYL-IKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLD 1356 + ++ G +L +L + + R + ++ +A ++G+ YLH++ I+HRD+K+ N+ L Sbjct: 381 ITQWCEGSSLYHHLHVADTRFDMVQ--LIDVARQTAQGMDYLHAKNIIHRDLKSNNIFLH 438 Query: 1357 TQRNLKIADFGVARVEAQ--NPKDMTGATGTLGYMAPEVL---DGKPYNRKCDVYSFGIC 1521 +KI DFG+A V+ + + + +G++ +MA EV+ D PY+ + DVY++G+ Sbjct: 439 EGLTVKIGDFGLATVKTRWSGAQPLEQPSGSVLWMAAEVIRMQDPNPYSFQSDVYAYGVV 498 Query: 1522 LWEVYCCDMPYPDLSFADVSSAVVHQN-LRPDIPRC---CPSAFANIMRKCWDGNPDKRP 1689 L+E+ +PY + D +V + L PD+ + CP A ++ C ++RP Sbjct: 499 LYELMTGSLPYSHIGCRDQIIFMVGRGYLSPDLSKISSNCPKAMRRLLSDCLKFQREERP 558 Query: 1690 DMDEVVQLMEALDTS 1734 +++ +E L S Sbjct: 559 LFPQILATIELLQRS 573
>P42686:SRK1_SPOLA Tyrosine-protein kinase isoform SRK1 - Spongilla lacustris| (Freshwater sponge) Length = 505 Score = 115 bits (289), Expect = 6e-25 Identities = 83/296 (28%), Positives = 137/296 (46%), Gaps = 3/296 (1%) Frame = +1 Query: 862 DWEIDLAKLEIRHVIAQGTYGTVYRGTYDGQ-QVAVKLLDWGEDGFATEAETTALRTSFK 1038 +WEI+ ++++ + G +G V+ G ++G VAVK L G T F Sbjct: 232 EWEIEKTQIKLLRRLGAGQFGEVWEGLWNGTTSVAVKTLKPG----------TMSVEEFL 281 Query: 1039 QEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQY 1218 QE ++ +L HP + + + I V E + G+L +Y Sbjct: 282 QEASIMKRLRHPKLIQLYAVCTKEEPIYI------------------VTELMKYGSLLEY 323 Query: 1219 LIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGVAR 1398 L + L + +V +A ++ G+SYL + +HRD+ N+L+ K+ADFG+AR Sbjct: 324 L-RGEDGVLKIEQLVDVAAQVASGMSYLEQQNYIHRDLAARNILVGEHGICKVADFGLAR 382 Query: 1399 V-EAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCD-MPYPDLSFA 1572 V + + + TGA + + APE + K DV+SFG+ L+E+ PYP ++ Sbjct: 383 VIDEEIYEAHTGAKFPIKWTAPEAAMYNRFTIKSDVWSFGVVLYEIITYGRFPYPGMTNP 442 Query: 1573 DVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDTSKG 1740 +V + QN R P CP F +IM CW +P RP + + +E S+G Sbjct: 443 EVLEK-IQQNYRMPCPANCPKQFHDIMLDCWREDPASRPTFETLQWQLEEFFNSEG 497
>P42685:FRK_HUMAN Tyrosine-protein kinase FRK - Homo sapiens (Human)| Length = 505 Score = 115 bits (288), Expect = 7e-25 Identities = 80/284 (28%), Positives = 133/284 (46%), Gaps = 6/284 (2%) Frame = +1 Query: 865 WEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQ-VAVKLLDWGEDGFATEAETTALRTSFKQ 1041 WEID +++ + G +G V+ G ++ VAVK L G F + Sbjct: 227 WEIDRNSIQLLKRLGSGQFGEVWEGLWNNTTPVAVKTLKPGSMD----------PNDFLR 276 Query: 1042 EVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYL 1221 E + L HP + + L+ P+ ++ E + G+L++YL Sbjct: 277 EAQIMKNLRHPKLIQLYAVCT----LEDPIY--------------IITELMRHGSLQEYL 318 Query: 1222 IKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGVARV 1401 + K+ V +A ++ G++YL SR +HRD+ N+L+ K+ADFG+ARV Sbjct: 319 QNDTGSKIHLTQQVDMAAQVASGMAYLESRNYIHRDLAARNVLVGEHNIYKVADFGLARV 378 Query: 1402 EAQNPKDMTGATGTL----GYMAPEVLDGKPYNRKCDVYSFGICLWEVYCC-DMPYPDLS 1566 + +D+ + + + APE + ++ K DV+SFGI L+E+ MPY ++ Sbjct: 379 FKVDNEDIYESRHEIKLPVKWTAPEAIRSNKFSIKSDVWSFGILLYEIITYGKMPYSGMT 438 Query: 1567 FADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMD 1698 A V ++ QN R P CP F NIM +CW+ P +RP + Sbjct: 439 GAQVIQ-MLAQNYRLPQPSNCPQQFYNIMLECWNAEPKERPTFE 481
>P53669:LIMK1_RAT LIM domain kinase 1 - Rattus norvegicus (Rat)| Length = 647 Score = 114 bits (286), Expect = 1e-24 Identities = 89/292 (30%), Positives = 138/292 (47%), Gaps = 17/292 (5%) Frame = +1 Query: 901 VIAQGTYGTVYRGTY--DGQQVAVKLLDWGEDGFATEAETTALRTSFKQEVAVWHKLSHP 1074 V+ +G +G + T+ G+ + +K L F E + T F +EV V L HP Sbjct: 344 VLGKGCFGQAIKVTHRETGEVMVMKELI----RFDEETQRT-----FLKEVKVMRCLEHP 394 Query: 1075 NVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYLIKNRRRKLAYK 1254 NV KF+G L + EY+ GGTL+ +IK+ + + Sbjct: 395 NVLKFIGVLYKDKRLNF------------------ITEYIKGGTLRG-IIKSMDSQYPWS 435 Query: 1255 VVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGVARV---EAQNPKDM 1425 V A D++ G++YLHS I+HRD+ + N L+ RN+ +ADFG+AR+ E +D+ Sbjct: 436 QRVSFAKDIASGMAYLHSMNIIHRDLNSHNCLVRENRNVVVADFGLARLMIDEKGQSEDL 495 Query: 1426 TG-----------ATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDMPYPDLSFA 1572 G +MAPE+++G+ Y+ K DV+SFGI L E+ PD Sbjct: 496 RSLKKPDRKKRYTVVGNPYWMAPEMINGRSYDEKVDVFSFGIVLCEIIGRVNADPDYLPR 555 Query: 1573 DVSSAV-VHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 + + V L P CP +F I +C D +P+KRP ++ Q +E L Sbjct: 556 TMDFGLNVRGFLDRYCPPNCPPSFFPITVRCCDLDPEKRPSFVKLEQWLETL 607
>Q8QFP8:LIMK1_CHICK LIM domain kinase 1 - Gallus gallus (Chicken)| Length = 662 Score = 114 bits (285), Expect = 2e-24 Identities = 88/292 (30%), Positives = 135/292 (46%), Gaps = 17/292 (5%) Frame = +1 Query: 901 VIAQGTYGTVYRGTY--DGQQVAVKLLDWGEDGFATEAETTALRTSFKQEVAVWHKLSHP 1074 V+ +G +G + T+ G+ + +K L F E + T F +EV V L HP Sbjct: 351 VLGKGCFGQAIKVTHRETGEVMVMKELI----RFDEETQRT-----FLKEVKVMRCLEHP 401 Query: 1075 NVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYLIKNRRRKLAYK 1254 NV KF+G L + EY+ GGTL+ LIK+ + Sbjct: 402 NVLKFIGVLYKEKRLNF------------------ITEYIKGGTLRG-LIKSMDSHYPWS 442 Query: 1255 VVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGVARV---EAQNPKDM 1425 V A D++ G++YLHS I+HRD+ + N L+ +++ +ADFG+AR+ E P+ + Sbjct: 443 QRVSFAKDIAAGMAYLHSMNIIHRDLNSHNCLVRENKSVVVADFGLARLMVDEKNQPEHL 502 Query: 1426 TG-----------ATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDMPYPD-LSF 1569 G +MAPE+++G+ Y+ K D++SFGI L E+ PD L Sbjct: 503 QNLKKPDRKKRYTVVGNPYWMAPEMINGRSYDEKVDIFSFGIVLCEIIGRVSADPDYLPR 562 Query: 1570 ADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 V L P CP +F I C D +P+KRP ++ Q +E L Sbjct: 563 TTDFGLNVRGFLERYCPPACPPSFFPIAACCCDLDPEKRPSFSKLEQWLETL 614
>P08103:HCK_MOUSE Tyrosine-protein kinase HCK - Mus musculus (Mouse)| Length = 524 Score = 114 bits (285), Expect = 2e-24 Identities = 81/296 (27%), Positives = 133/296 (44%), Gaps = 3/296 (1%) Frame = +1 Query: 856 KADWEIDLAKLEIRHVIAQGTYGTVYRGTYDGQ-QVAVKLLDWGEDGFATEAETTALRTS 1032 K WEI L++ + G +G V+ TY+ +VAVK + G + EA Sbjct: 250 KDAWEIPRESLQMEKKLGAGQFGEVWMATYNKHTKVAVKTMKPGS--MSVEA-------- 299 Query: 1033 FKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLK 1212 F E + L H + K A + +V E++A G+L Sbjct: 300 FLAEANLMKSLQHDKLVKL-------------------HAVVSQEPIFIVTEFMAKGSLL 340 Query: 1213 QYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGV 1392 +L K ++ + +S G++++ R +HRD++ N+L+ KIADFG+ Sbjct: 341 DFLKSEEGSKQPLPKLIDFSAQISEGMAFIEQRNYIHRDLRAANILVSASLVCKIADFGL 400 Query: 1393 ARVEAQNP-KDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCD-MPYPDLS 1566 AR+ N GA + + APE ++ + K DV+SFGI L E+ +PYP +S Sbjct: 401 ARIIEDNEYTAREGAKFPIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMS 460 Query: 1567 FADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDTS 1734 +V A+ H R P CP NIM +CW P++RP + + +++ T+ Sbjct: 461 NPEVIRALEH-GYRMPRPDNCPEELYNIMIRCWKNRPEERPTFEYIQSVLDDFYTA 515
>P08631:HCK_HUMAN Tyrosine-protein kinase HCK - Homo sapiens (Human)| Length = 526 Score = 114 bits (285), Expect = 2e-24 Identities = 83/313 (26%), Positives = 140/313 (44%), Gaps = 3/313 (0%) Frame = +1 Query: 805 QQLNKKWSKSNIKSLGPKADWEIDLAKLEIRHVIAQGTYGTVYRGTYDGQ-QVAVKLLDW 981 Q+L+ S + K WEI L++ + G +G V+ TY+ +VAVK + Sbjct: 235 QKLSVPCMSSKPQKPWEKDAWEIPRESLKLEKKLGAGQFGEVWMATYNKHTKVAVKTMKP 294 Query: 982 GEDGFATEAETTALRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLP 1161 G + EA F E V L H + K A + Sbjct: 295 GS--MSVEA--------FLAEANVMKTLQHDKLVKL-------------------HAVVT 325 Query: 1162 ARACCVVVEYLAGGTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTE 1341 ++ E++A G+L +L + K ++ + ++ G++++ R +HRD++ Sbjct: 326 KEPIYIITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAA 385 Query: 1342 NMLLDTQRNLKIADFGVARVEAQNP-KDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGI 1518 N+L+ KIADFG+ARV N GA + + APE ++ + K DV+SFGI Sbjct: 386 NILVSASLVCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGSFTIKSDVWSFGI 445 Query: 1519 CLWEVYCCD-MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDM 1695 L E+ +PYP +S +V A + + R P CP NIM +CW P++RP Sbjct: 446 LLMEIVTYGRIPYPGMSNPEVIRA-LERGYRMPRPENCPEELYNIMMRCWKNRPEERPTF 504 Query: 1696 DEVVQLMEALDTS 1734 + + +++ T+ Sbjct: 505 EYIQSVLDDFYTA 517
>P51813:BMX_HUMAN Cytoplasmic tyrosine-protein kinase BMX - Homo sapiens (Human)| Length = 675 Score = 114 bits (285), Expect = 2e-24 Identities = 82/289 (28%), Positives = 131/289 (45%), Gaps = 2/289 (0%) Frame = +1 Query: 865 WEIDLAKLEIRHVIAQGTYGTVYRGTYDGQ-QVAVKLLDWGEDGFATEAETTALRTSFKQ 1041 WE+ ++ + + G +G V G + GQ VAVK++ ++G +E E F Q Sbjct: 410 WELKREEITLLKELGSGQFGVVQLGKWKGQYDVAVKMI---KEGSMSEDE-------FFQ 459 Query: 1042 EVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYL 1221 E KLSHP + KF G + P+ +V EY++ G L YL Sbjct: 460 EAQTMMKLSHPKLVKFYGVC----SKEYPIY--------------IVTEYISNGCLLNYL 501 Query: 1222 IKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGVAR- 1398 ++ + L ++++ D+ G+++L S + +HRD+ N L+D +K++DFG+ R Sbjct: 502 -RSHGKGLEPSQLLEMCYDVCEGMAFLESHQFIHRDLAARNCLVDRDLCVKVSDFGMTRY 560 Query: 1399 VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDMPYPDLSFADV 1578 V G + + APEV Y+ K DV++FGI +WEV+ DL Sbjct: 561 VLDDQYVSSVGTKFPVKWSAPEVFHYFKYSSKSDVWAFGILMWEVFSLGKQPYDLYDNSQ 620 Query: 1579 SSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 V Q R P IM CW P+KRP +++ +E L Sbjct: 621 VVLKVSQGHRLYRPHLASDTIYQIMYSCWHELPEKRPTFQQLLSSIEPL 669
>P16277:BLK_MOUSE Tyrosine-protein kinase BLK - Mus musculus (Mouse)| Length = 499 Score = 114 bits (285), Expect = 2e-24 Identities = 77/303 (25%), Positives = 137/303 (45%), Gaps = 2/303 (0%) Frame = +1 Query: 841 KSLGPKADWEIDLAKLEIRHVIAQGTYGTVYRGTY-DGQQVAVKLLDWGEDGFATEAETT 1017 K+L + +WEI L++ + G +G V+ G Y + +VA+K L G T Sbjct: 220 KNLWAQDEWEIPRQSLKLVRKLGSGQFGEVWMGYYKNNMKVAIKTLKEG----------T 269 Query: 1018 ALRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLA 1197 +F E V L H + + A + +V EY+A Sbjct: 270 MSPEAFLGEANVMKTLQHERLVRLY-------------------AVVTREPIYIVTEYMA 310 Query: 1198 GGTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKI 1377 G L +L + +L+ ++ ++ ++ G++Y+ +HRD++ N+L+ KI Sbjct: 311 RGCLLDFLKTDEGSRLSLPRLIDMSAQVAEGMAYIERMNSIHRDLRAANILVSETLCCKI 370 Query: 1378 ADFGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCD-MPY 1554 ADFG+AR+ GA + + APE + + K DV+SFG+ L + +PY Sbjct: 371 ADFGLARIIDSEYTAQEGAKFPIKWTAPEAIHFGVFTIKADVWSFGVLLMVIVTYGRVPY 430 Query: 1555 PDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDTS 1734 P +S +V ++ H P C P + +I+ +CW G P++RP + + ++E T+ Sbjct: 431 PGMSNPEVIRSLEHGYRMPCPETCPPELYNDIITECWRGRPEERPTFEFLQSVLEDFYTA 490 Query: 1735 KGG 1743 G Sbjct: 491 TEG 493
>P00527:YES_AVISY Tyrosine-protein kinase transforming protein YES - Avian sarcoma| virus (strain Y73) Length = 528 Score = 114 bits (284), Expect = 2e-24 Identities = 82/291 (28%), Positives = 135/291 (46%), Gaps = 3/291 (1%) Frame = +1 Query: 856 KADWEIDLAKLEIRHVIAQGTYGTVYRGTYDGQ-QVAVKLLDWGEDGFATEAETTALRTS 1032 K WEI L + + QG +G V+ GT++G +VA+K L G T + + Sbjct: 257 KDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTKVAIKTLKLG----------TMMPEA 306 Query: 1033 FKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLK 1212 F QE + KL H D +P+ A + +V E++ G+L Sbjct: 307 FLQEAQIMKKLRH--------------DKLVPLY-----AVVSEEPIYIVTEFMTKGSLL 347 Query: 1213 QYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGV 1392 +L + + L +V +A ++ G++Y+ +HRD++ N+L+ KIADFG+ Sbjct: 348 DFLKEGEGKFLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGDNLVCKIADFGL 407 Query: 1393 AR-VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCD-MPYPDLS 1566 AR +E GA + + APE + K DV+SFGI L E+ +PYP + Sbjct: 408 ARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMV 467 Query: 1567 FADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 1719 +V V + R P+ CP + +M+ CW +PD+RP + + +E Sbjct: 468 NREVLEQ-VERGYRMPCPQGCPESLHELMKLCWKKDPDERPTFEYIQSFLE 517
>P11346:KRAF1_DROME Raf homolog serine/threonine-protein kinase dRAF-1 - Drosophila| melanogaster (Fruit fly) Length = 739 Score = 114 bits (284), Expect = 2e-24 Identities = 83/295 (28%), Positives = 145/295 (49%), Gaps = 9/295 (3%) Frame = +1 Query: 862 DWEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFATEAETTALRTSFKQ 1041 +W I ++ I I G++GTVYR + G VAVK L+ + + A +FK Sbjct: 421 NWNILAEEILIGPRIGSGSFGTVYRAHWHGP-VAVKTLN-------VKTPSPAQLQAFKN 472 Query: 1042 EVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYL 1221 EVA+ K H N+ F+G + P+ A +V ++ G +L ++ Sbjct: 473 EVAMLKKTRHCNILLFMGC-----------------VSKPSLA--IVTQWCEGSSLYKH- 512 Query: 1222 IKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGVARV 1401 + K ++ + +++G+ YLH++ I+HRD+K+ N+ L ++KI DFG+A Sbjct: 513 VHVSETKFKLNTLIDIGRQVAQGMDYLHAKNIIHRDLKSNNIFLHEDLSVKIGDFGLATA 572 Query: 1402 EAQ--NPKDMTGATGTLGYMAPEVL---DGKPYNRKCDVYSFGICLWEVYCCDMPYPDLS 1566 + + K TG++ +MAPEV+ + PY+ + DVY+FGI ++E+ +PY +S Sbjct: 573 KTRWSGEKQANQPTGSILWMAPEVIRMQELNPYSFQSDVYAFGIVMYELLAECLPYGHIS 632 Query: 1567 FADVSSAVVHQN-LRPDIPRC---CPSAFANIMRKCWDGNPDKRPDMDEVVQLME 1719 D +V + LRPD+ + P A + C P RP ++ ++E Sbjct: 633 NKDQILFMVGRGLLRPDMSQVRSDAPQALKRLAEDCIKYTPKDRPLFRPLLNMLE 687
>P06213:INSR_HUMAN Insulin receptor precursor - Homo sapiens (Human)| Length = 1382 Score = 114 bits (284), Expect = 2e-24 Identities = 88/305 (28%), Positives = 139/305 (45%), Gaps = 19/305 (6%) Frame = +1 Query: 862 DWEIDLAKLEIRHVIAQGTYGTVYRGT----YDGQ---QVAVKLLDWGEDGFATEAETTA 1020 +WE+ K+ + + QG++G VY G G+ +VAVK ++ E+ + Sbjct: 1015 EWEVSREKITLLRELGQGSFGMVYEGNARDIIKGEAETRVAVKTVN--------ESASLR 1066 Query: 1021 LRTSFKQEVAVWHKLSHPNVTKFVGA-SMGTTDLKIPVNDNGARANLPARACCVVVEYLA 1197 R F E +V + +V + +G S G L VV+E +A Sbjct: 1067 ERIEFLNEASVMKGFTCHHVVRLLGVVSKGQPTL-------------------VVMELMA 1107 Query: 1198 GGTLKQYLIKNR--------RRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLL 1353 G LK YL R R + ++Q+A +++ G++YL+++K VHRD+ N ++ Sbjct: 1108 HGDLKSYLRSLRPEAENNPGRPPPTLQEMIQMAAEIADGMAYLNAKKFVHRDLAARNCMV 1167 Query: 1354 DTQRNLKIADFGVARVEAQNPKDMTGATGTL--GYMAPEVLDGKPYNRKCDVYSFGICLW 1527 +KI DFG+ R + G G L +MAPE L + D++SFG+ LW Sbjct: 1168 AHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMAPESLKDGVFTTSSDMWSFGVVLW 1227 Query: 1528 EV-YCCDMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEV 1704 E+ + PY LS V V+ D P CP ++MR CW NP RP E+ Sbjct: 1228 EITSLAEQPYQGLSNEQVLKFVMDGGYL-DQPDNCPERVTDLMRMCWQFNPKMRPTFLEI 1286 Query: 1705 VQLME 1719 V L++ Sbjct: 1287 VNLLK 1291
>Q498D6:FGFR4_RAT Fibroblast growth factor receptor 4 precursor - Rattus norvegicus| (Rat) Length = 800 Score = 114 bits (284), Expect = 2e-24 Identities = 70/201 (34%), Positives = 105/201 (52%), Gaps = 17/201 (8%) Frame = +1 Query: 1177 VVVEYLAGGTLKQYLIKNR--------------RRKLAYKVVVQLALDLSRGLSYLHSRK 1314 V+VEY A G L+++L R L++ +V A ++RG+ YL SRK Sbjct: 546 VIVEYAAKGNLREFLRARRPPGPDLSPDGPRSSEGPLSFPALVSCAYQVARGMQYLESRK 605 Query: 1315 IVHRDVKTENMLLDTQRNLKIADFGVAR--VEAQNPKDMTGATGTLGYMAPEVLDGKPYN 1488 +HRD+ N+L+ +KIADFG+AR K + + +MAPE L + Y Sbjct: 606 CIHRDLAARNVLVTEDDVMKIADFGLARGVHHIDYYKKTSNGRLPVKWMAPEALFDRVYT 665 Query: 1489 RKCDVYSFGICLWEVYCC-DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCW 1665 + DV+SFGI LWE++ PYP + ++ S ++ + R + P CPS +MR+CW Sbjct: 666 HQSDVWSFGILLWEIFTLGGSPYPGIPVEELFS-LLREGHRMERPPNCPSELYGLMRECW 724 Query: 1666 DGNPDKRPDMDEVVQLMEALD 1728 P +RP QL+EALD Sbjct: 725 HAAPSQRPTFK---QLVEALD 742
>P22455:FGFR4_HUMAN Fibroblast growth factor receptor 4 precursor - Homo sapiens (Human)| Length = 802 Score = 114 bits (284), Expect = 2e-24 Identities = 89/305 (29%), Positives = 136/305 (44%), Gaps = 17/305 (5%) Frame = +1 Query: 865 WEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFATEAETTALRTSFKQE 1044 WE +L + + +G +G V R G A D +T A + ++ Sbjct: 460 WEFPRDRLVLGKPLGEGCFGQVVRAEAFGMDPA------RPDQASTVAVKMLKDNASDKD 513 Query: 1045 VAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYLI 1224 +A +S V K +G +L G V+VE A G L+++L Sbjct: 514 LA--DLVSEMEVMKLIGRHKNIINLLGVCTQEGP--------LYVIVECAAKGNLREFLR 563 Query: 1225 KNR--------------RRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQ 1362 R L++ V+V A ++RG+ YL SRK +HRD+ N+L+ Sbjct: 564 ARRPPGPDLSPDGPRSSEGPLSFPVLVSCAYQVARGMQYLESRKCIHRDLAARNVLVTED 623 Query: 1363 RNLKIADFGVAR--VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVY 1536 +KIADFG+AR K + + +MAPE L + Y + DV+SFGI LWE++ Sbjct: 624 NVMKIADFGLARGVHHIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIF 683 Query: 1537 CC-DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQL 1713 PYP + ++ S ++ + R D P CP +MR+CW P +RP QL Sbjct: 684 TLGGSPYPGIPVEELFS-LLREGHRMDRPPHCPPELYGLMRECWHAAPSQRPTFK---QL 739 Query: 1714 MEALD 1728 +EALD Sbjct: 740 VEALD 744
>P10936:YES_XENLA Tyrosine-protein kinase Yes - Xenopus laevis (African clawed frog)| Length = 537 Score = 113 bits (283), Expect = 3e-24 Identities = 83/291 (28%), Positives = 135/291 (46%), Gaps = 3/291 (1%) Frame = +1 Query: 856 KADWEIDLAKLEIRHVIAQGTYGTVYRGTYDGQ-QVAVKLLDWGEDGFATEAETTALRTS 1032 K WEI L + + QG +G V+ GT++G +VA+K L G T + + Sbjct: 261 KDAWEIPRESLRLDVKLGQGCFGEVWIGTWNGTTKVAIKTLKPG----------TMMPEA 310 Query: 1033 FKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLK 1212 F QE + KL H D +P+ A + +V EY+ G+L Sbjct: 311 FLQEAQIMKKLRH--------------DKLVPLY-----AVVSEEPIYIVTEYMIKGSLL 351 Query: 1213 QYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGV 1392 +L + + L +V +A ++ G++Y+ +HRD++ N+L+ KIADFG+ Sbjct: 352 DFLKEGNGKYLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGDNLVCKIADFGL 411 Query: 1393 AR-VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCD-MPYPDLS 1566 AR +E GA + + APE + K DV+SFGI L E+ +PYP + Sbjct: 412 ARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVAKGRVPYPGMV 471 Query: 1567 FADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 1719 +V V + R P+ CP + +M+ CW +PD+RP + + +E Sbjct: 472 NREVLEQ-VERGYRMPCPQRCPESLHELMKLCWKKDPDERPTFEYIQSFLE 521
>Q9PVZ4:INSR_XENLA Insulin receptor precursor - Xenopus laevis (African clawed frog)| Length = 1362 Score = 113 bits (283), Expect = 3e-24 Identities = 87/305 (28%), Positives = 142/305 (46%), Gaps = 19/305 (6%) Frame = +1 Query: 862 DWEIDLAKLEIRHVIAQGTYGTVYRGT----YDGQ---QVAVKLLDWGEDGFATEAETTA 1020 +WE+ K+ + + QG++G VY G G+ +VAVK ++ E+ + Sbjct: 1004 EWEVPRDKINLLRELGQGSFGMVYEGIAKDIIKGEPEVRVAVKTVN--------ESASLR 1055 Query: 1021 LRTSFKQEVAVWHKLSHPNVTKFVGA-SMGTTDLKIPVNDNGARANLPARACCVVVEYLA 1197 R F E +V + +V + +G S G L V++E +A Sbjct: 1056 ERIEFLNEASVMKAFNCHHVVRLLGVVSKGQPTL-------------------VIMELMA 1096 Query: 1198 GGTLKQYL------IKNRRRKLA--YKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLL 1353 G LK YL +N +LA K ++Q+A ++S G++YL+++K VHRD+ N ++ Sbjct: 1097 HGDLKSYLRSLRPDAENNPGRLAPTLKEIIQMAAEISDGMAYLNAKKFVHRDLAARNCMV 1156 Query: 1354 DTQRNLKIADFGVARVEAQNPKDMTGATGTL--GYMAPEVLDGKPYNRKCDVYSFGICLW 1527 +KI DFG+ R + G G L +M+PE L + DV+SFG+ LW Sbjct: 1157 ADDYAVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTAFSDVWSFGVVLW 1216 Query: 1528 EV-YCCDMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEV 1704 E+ + PY LS V V+ D P CP ++M+ CW NP RP E+ Sbjct: 1217 EITSLAEQPYQGLSNEQVLKFVMDGG-SLDHPENCPPRLHSLMQMCWQYNPKMRPTFLEI 1275 Query: 1705 VQLME 1719 + +++ Sbjct: 1276 IDMLK 1280
>P22607:FGFR3_HUMAN Fibroblast growth factor receptor 3 precursor - Homo sapiens (Human)| Length = 806 Score = 113 bits (283), Expect = 3e-24 Identities = 99/360 (27%), Positives = 157/360 (43%), Gaps = 46/360 (12%) Frame = +1 Query: 832 SNIKSLGPKAD--WEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQ---------VAVKLLD 978 +N+ L AD WE+ A+L + + +G +G V G VAVK+L Sbjct: 452 ANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLK 511 Query: 979 WGEDGFATEAETTALRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANL 1158 +D AT+ + + L + + + H N+ +GA L Sbjct: 512 --DD--ATDKDLSDLVSEMEMMKMIG---KHKNIINLLGACTQGGPLY------------ 552 Query: 1159 PARACCVVVEYLAGGTLKQYLIKNR--------------RRKLAYKVVVQLALDLSRGLS 1296 V+VEY A G L+++L R +L +K +V A ++RG+ Sbjct: 553 ------VLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGME 606 Query: 1297 YLHSRKIVHRDVKTENMLLDTQRNLKIADFGVARVEAQN---PKDMTGATGTLGYMAPEV 1467 YL S+K +HRD+ N+L+ +KIADFG+AR + N K T + +MAPE Sbjct: 607 YLASQKCIHRDLAARNVLVTEDNVMKIADFGLAR-DVHNLDYYKKTTNGRLPVKWMAPEA 665 Query: 1468 LDGKPYNRKCDVYSFGICLWEVYCC-DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFA 1644 L + Y + DV+SFG+ LWE++ PYP + ++ ++ + R D P C Sbjct: 666 LFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFK-LLKEGHRMDKPANCTHDLY 724 Query: 1645 NIMRKCWDGNPDKRPDMDEVVQLMEALDT-----------------SKGGGMIPDGQSSG 1773 IMR+CW P +RP ++V+ ++ + T S GG P SSG Sbjct: 725 MIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSG 784
>P09759:EPHB1_RAT Ephrin type-B receptor 1 precursor - Rattus norvegicus (Rat)| Length = 984 Score = 113 bits (283), Expect = 3e-24 Identities = 82/298 (27%), Positives = 141/298 (47%), Gaps = 12/298 (4%) Frame = +1 Query: 868 EIDLAKLEIRHVIAQGTYGTVYRGTYD--GQQ---VAVKLLDWGEDGFATEAETTALRTS 1032 EID++ ++I VI G +G VY+G G++ VA+K L G + R Sbjct: 613 EIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGY--------SEKQRRD 664 Query: 1033 FKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLK 1212 F E ++ + HPN+ + G +R ++ E++ G L Sbjct: 665 FLSEASIMGQFDHPNIIRLEGVVT------------------KSRPVMIITEFMENGALD 706 Query: 1213 QYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGV 1392 +L +N + ++V L ++ G+ YL VHRD+ N+L+++ K++DFG+ Sbjct: 707 SFLRQNDGQFTVIQLVGMLR-GIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGL 765 Query: 1393 ARVEAQNPKDMTGATGTLG------YMAPEVLDGKPYNRKCDVYSFGICLWEVYCC-DMP 1551 +R + D T T +LG + APE + + + DV+S+GI +WEV + P Sbjct: 766 SRYLQDDTSDPT-YTSSLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGERP 824 Query: 1552 YPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 Y D+S DV +A + Q+ R P CP+A +M CW + + RP E+V ++ + Sbjct: 825 YWDMSNQDVINA-IEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKM 881
>Q8CBF3:EPHB1_MOUSE Ephrin type-B receptor 1 precursor - Mus musculus (Mouse)| Length = 984 Score = 113 bits (283), Expect = 3e-24 Identities = 82/298 (27%), Positives = 141/298 (47%), Gaps = 12/298 (4%) Frame = +1 Query: 868 EIDLAKLEIRHVIAQGTYGTVYRGTYD--GQQ---VAVKLLDWGEDGFATEAETTALRTS 1032 EID++ ++I VI G +G VY+G G++ VA+K L G + R Sbjct: 613 EIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGY--------SEKQRRD 664 Query: 1033 FKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLK 1212 F E ++ + HPN+ + G +R ++ E++ G L Sbjct: 665 FLSEASIMGQFDHPNIIRLEGVVT------------------KSRPVMIITEFMENGALD 706 Query: 1213 QYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGV 1392 +L +N + ++V L ++ G+ YL VHRD+ N+L+++ K++DFG+ Sbjct: 707 SFLRQNDGQFTVIQLVGMLR-GIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGL 765 Query: 1393 ARVEAQNPKDMTGATGTLG------YMAPEVLDGKPYNRKCDVYSFGICLWEVYCC-DMP 1551 +R + D T T +LG + APE + + + DV+S+GI +WEV + P Sbjct: 766 SRYLQDDTSDPT-YTSSLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGERP 824 Query: 1552 YPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 Y D+S DV +A + Q+ R P CP+A +M CW + + RP E+V ++ + Sbjct: 825 YWDMSNQDVINA-IEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKM 881
>Q07494:EPHB1_CHICK Ephrin type-B receptor 1 - Gallus gallus (Chicken)| Length = 984 Score = 113 bits (283), Expect = 3e-24 Identities = 82/298 (27%), Positives = 142/298 (47%), Gaps = 12/298 (4%) Frame = +1 Query: 868 EIDLAKLEIRHVIAQGTYGTVYRGTYD--GQQ---VAVKLLDWGEDGFATEAETTALRTS 1032 EID++ ++I VI G +G VY+G G++ VA+K L G + R Sbjct: 613 EIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGY--------SEKQRRD 664 Query: 1033 FKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLK 1212 F E ++ + HPN+ + G +R ++ E++ G L Sbjct: 665 FLSEASIMGQFDHPNIIRLEGVVT------------------KSRPVMIITEFMENGALD 706 Query: 1213 QYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGV 1392 +L +N + ++V L ++ G+ YL VHRD+ N+L+++ K++DFG+ Sbjct: 707 SFLRQNDGQFTVIQLVGMLR-GIAAGMKYLAEMNYVHRDLAARNILVNSNLVCKVSDFGL 765 Query: 1393 ARVEAQNPKDMTGATGTLG------YMAPEVLDGKPYNRKCDVYSFGICLWEVYCC-DMP 1551 +R + D T T +LG + APE + + + DV+S+GI +WEV + P Sbjct: 766 SRYLQDDTSDPT-YTSSLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGERP 824 Query: 1552 YPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 Y D+S DV +A + Q+ R P CP+A +M CW + + RP + E+V ++ + Sbjct: 825 YWDMSNQDVINA-IEQDYRLPPPMDCPAALHQLMLDCWQKDRNTRPRLAEIVNTLDKM 881
>P09324:YES_CHICK Tyrosine-protein kinase Yes - Gallus gallus (Chicken)| Length = 541 Score = 113 bits (282), Expect = 4e-24 Identities = 82/291 (28%), Positives = 135/291 (46%), Gaps = 3/291 (1%) Frame = +1 Query: 856 KADWEIDLAKLEIRHVIAQGTYGTVYRGTYDGQ-QVAVKLLDWGEDGFATEAETTALRTS 1032 K WEI L + + QG +G V+ GT++G +VA+K L G T + + Sbjct: 265 KDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTKVAIKTLKPG----------TMMPEA 314 Query: 1033 FKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLK 1212 F QE + KL H D +P+ A + +V E++ G+L Sbjct: 315 FLQEAQIMKKLRH--------------DKLVPLY-----AVVSEEPIYIVTEFMTKGSLL 355 Query: 1213 QYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGV 1392 +L + + L +V +A ++ G++Y+ +HRD++ N+L+ KIADFG+ Sbjct: 356 DFLKEGEGKFLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGDNLVCKIADFGL 415 Query: 1393 AR-VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCD-MPYPDLS 1566 AR +E GA + + APE + K DV+SFGI L E+ +PYP + Sbjct: 416 ARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMV 475 Query: 1567 FADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 1719 +V V + R P+ CP + +M+ CW +PD+RP + + +E Sbjct: 476 NREVLEQ-VERGYRMPCPQGCPESLHELMKLCWKKDPDERPTFEYIQSFLE 525
>Q9V9J3:SRC42_DROME Tyrosine-protein kinase Src42A - Drosophila melanogaster (Fruit fly)| Length = 517 Score = 113 bits (282), Expect = 4e-24 Identities = 82/295 (27%), Positives = 138/295 (46%), Gaps = 5/295 (1%) Frame = +1 Query: 865 WEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQ-VAVKLLDWGEDGFATEAETTALRTSFKQ 1041 WEID L+ + G +G V+ G ++ VA+K L G T F Sbjct: 241 WEIDRTSLKFVRKLGSGQFGDVWEGLWNNTTPVAIKTLKSG----------TMDPKDFLA 290 Query: 1042 EVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYL 1221 E + KL H + + ++ P+ ++ E + G+L +YL Sbjct: 291 EAQIMKKLRHTKLIQLYAVCT----VEEPIY--------------IITELMKHGSLLEYL 332 Query: 1222 --IKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGVA 1395 I + R L + ++ +A ++ G++YL S+ +HRD+ N+L+ +KIADFG+A Sbjct: 333 QAIAGKGRSLKMQTLIDMAAQIAAGMAYLESQNYIHRDLAARNVLVGDGNIVKIADFGLA 392 Query: 1396 R-VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCD-MPYPDLSF 1569 R ++ + GA + + APE + ++ K DV+SFGI L E+ +PYP ++ Sbjct: 393 RLIKEDEYEARVGARFPIKWTAPEAANYSKFSIKSDVWSFGILLTELVTYGRIPYPGMTN 452 Query: 1570 ADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDTS 1734 A+V + V H P P C P + IM +CW +P +RP + + +E TS Sbjct: 453 AEVLTQVEHGYRMPQPPNCEPRLY-EIMLECWHKDPMRRPTFETLQWKLEDFYTS 506
>Q78DX7:ROS_MOUSE Proto-oncogene tyrosine-protein kinase ROS precursor - Mus musculus| (Mouse) Length = 2340 Score = 113 bits (282), Expect = 4e-24 Identities = 92/295 (31%), Positives = 134/295 (45%), Gaps = 21/295 (7%) Frame = +1 Query: 883 KLEIRHVIAQGTYGTVYRGTY-------DGQ-QVAVKLLDWGEDGFATEAETTALRTSFK 1038 KL +R ++ G +G VY GT G+ +VAVK L G +T+ E + F Sbjct: 1937 KLSLRLLLGSGAFGEVYEGTAIDILGVGSGEIKVAVKTLKKG----STDQE----KIEFL 1988 Query: 1039 QEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQY 1218 +E + K +HPN+ K +G L +++E + GG L Y Sbjct: 1989 KEAHLMSKFNHPNILKQLGVC------------------LLGEPQYIILELMEGGDLLSY 2030 Query: 1219 LIKNRRR-----KLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQ-----RN 1368 L K R L +V+L +D+S+G YL +HRD+ N L+ + R Sbjct: 2031 LRKARGTTFHGPSLTLLDLVELCVDISKGCVYLEQMHFIHRDLAARNCLVSVKDYTSPRV 2090 Query: 1369 LKIADFGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEVYCC 1542 +KI DFG+AR +N G L +MAPE L + + DV+SFGI +WE+ Sbjct: 2091 VKIGDFGLAREIYKNDYYRKRGEGLLPVRWMAPENLMDGIFTSQSDVWSFGILVWEILTL 2150 Query: 1543 D-MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEV 1704 PYP S DV + V R + PR CP N+M +CW PD+RP + Sbjct: 2151 GHQPYPAHSNLDVLN-YVQAGGRLEPPRNCPDDLWNLMSQCWAQEPDQRPTFHNI 2204
>P00537:MOS_MSVMM Serine/threonine-protein kinase-transforming protein mos - Moloney| murine sarcoma virus (strain m1) Length = 376 Score = 113 bits (282), Expect = 4e-24 Identities = 87/302 (28%), Positives = 146/302 (48%), Gaps = 12/302 (3%) Frame = +1 Query: 865 WEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFATEAETTALRTSFKQE 1044 + ID ++ + H + G +G+VY+ TY G VA+K ++ + A + SF E Sbjct: 87 FSIDWEQVCLMHRLGSGGFGSVYKATYHGVPVAIKQVN------KCTKDLRASQRSFWAE 140 Query: 1045 VAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYLI 1224 + + +L H N+ + V AS T P + N + V + + G + Sbjct: 141 LNI-ARLRHDNIVRVVAASTRT-----PEDSNSLGTIIMEFGGNVTLHQVIYGATRSPEP 194 Query: 1225 KNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGVA--- 1395 + R +L+ ++ +LD+ GL +LHS+ I+H D+K N+L+ Q KI+DFG + Sbjct: 195 LSCREQLSLGKCLKYSLDVVNGLLFLHSQSILHLDLKPANILISEQDVCKISDFGCSQKL 254 Query: 1396 ---RVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDMPYPDLS 1566 R +P + GT + APE+L G+ K D+YSFGI LW++ ++PY Sbjct: 255 QDLRCRQASPHHI---GGTYTHQAPEILKGEIATPKADIYSFGITLWQMTTREVPYSG-E 310 Query: 1567 FADVSSAVVHQNLRPDIPRCCPSA------FANIMRKCWDGNPDKRPDMDEVVQLMEALD 1728 V AVV NLRP + +A NI++ CW+ +RP + + + ++AL Sbjct: 311 PQYVQYAVVAYNLRPSLAGAVFTASLTGKTLQNIIQSCWEARALQRPGAELLQRDLKALA 370 Query: 1729 TS 1734 S Sbjct: 371 DS 372
>P18106:FPS_DROME Tyrosine-protein kinase Fps85D - Drosophila melanogaster (Fruit fly)| Length = 1325 Score = 113 bits (282), Expect = 4e-24 Identities = 77/290 (26%), Positives = 132/290 (45%), Gaps = 3/290 (1%) Frame = +1 Query: 865 WEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQ--VAVKLLDWGEDGFATEAETTALRTSFK 1038 WE+ + + I +G +G VY+ + VAVK + F Sbjct: 1056 WELSNDDVVLLERIGRGNFGDVYKAKLKSTKLDVAVKT--------CRMTLPDEQKRKFL 1107 Query: 1039 QEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQY 1218 QE + + HPN+ K +G + K P+ +V+E + GG+L Y Sbjct: 1108 QEGRILKQYDHPNIVKLIGICVQ----KQPI--------------MIVMELVLGGSLLTY 1149 Query: 1219 LIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGVAR 1398 L KN L + + + D + G+ YL S+ +HRD+ N L+D + ++KI+DFG++R Sbjct: 1150 LRKNSNG-LTTRQQMGMCRDAAAGMRYLESKNCIHRDLAARNCLVDLEHSVKISDFGMSR 1208 Query: 1399 VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYC-CDMPYPDLSFAD 1575 E + + + APE L+ Y CDV+S+GI +WE++ D PY ++ + Sbjct: 1209 EEEEYIVSDGMKQIPVKWTAPEALNFGKYTSLCDVWSYGILMWEIFSKGDTPYSGMTNSR 1268 Query: 1576 VSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 + R P+ P +M +CW + + RP DE+ +++AL Sbjct: 1269 ARER-IDTGYRMPTPKSTPEEMYRLMLQCWAADAESRPHFDEIYNVVDAL 1317
>Q91287:FGFR3_PLEWA Fibroblast growth factor receptor 3 precursor - Pleurodeles waltlii| (Iberian ribbed newt) Length = 796 Score = 113 bits (282), Expect = 4e-24 Identities = 91/329 (27%), Positives = 151/329 (45%), Gaps = 29/329 (8%) Frame = +1 Query: 832 SNIKSLGPKAD--WEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQ---------VAVKLLD 978 +N+ L AD WE+ ++L + + +G +G V G + VAVK+L Sbjct: 437 ANVSELELPADPKWELSRSRLTLGKPLGEGCFGQVVMADAVGIEKDKPNKATSVAVKMLK 496 Query: 979 WGEDGFATEAETTALRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANL 1158 +D AT+ + + L + + + H N+ +GA L Sbjct: 497 --DD--ATDKDLSDLVSEMEMMKMIG---KHKNIINLLGACTQDGPLY------------ 537 Query: 1159 PARACCVVVEYLAGGTLKQYLIKNR--------------RRKLAYKVVVQLALDLSRGLS 1296 V+VEY + G L++YL R +L +K +V A ++RG+ Sbjct: 538 ------VLVEYASKGNLREYLRARRPPGMDYSFDTCKLPEEQLTFKDLVSCAYQVARGME 591 Query: 1297 YLHSRKIVHRDVKTENMLLDTQRNLKIADFGVARVEAQN---PKDMTGATGTLGYMAPEV 1467 YL S+K +HRD+ N+L+ +KIADFG+AR + N K T + +MAPE Sbjct: 592 YLASQKCIHRDLAARNVLVTDDNVMKIADFGLAR-DVHNIDYYKKTTNGRLPVKWMAPEA 650 Query: 1468 LDGKPYNRKCDVYSFGICLWEVYCC-DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFA 1644 L + Y + DV+SFG+ LWE++ PYP + ++ ++ + R D P C Sbjct: 651 LFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFK-LLKEGHRMDKPANCTHELY 709 Query: 1645 NIMRKCWDGNPDKRPDMDEVVQLMEALDT 1731 IMR+CW P +RP ++V+ ++ + T Sbjct: 710 MIMRECWHAVPSQRPTFKQLVEDLDRVLT 738
>P54762:EPHB1_HUMAN Ephrin type-B receptor 1 precursor - Homo sapiens (Human)| Length = 984 Score = 113 bits (282), Expect = 4e-24 Identities = 82/298 (27%), Positives = 141/298 (47%), Gaps = 12/298 (4%) Frame = +1 Query: 868 EIDLAKLEIRHVIAQGTYGTVYRGTYD--GQQ---VAVKLLDWGEDGFATEAETTALRTS 1032 EID++ ++I VI G +G VY+G G++ VA+K L G + R Sbjct: 613 EIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGY--------SEKQRRD 664 Query: 1033 FKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLK 1212 F E ++ + HPN+ + G +R ++ E++ G L Sbjct: 665 FLSEASIMGQFDHPNIIRLEGVVT------------------KSRPVMIITEFMENGALD 706 Query: 1213 QYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGV 1392 +L +N + ++V L ++ G+ YL VHRD+ N+L+++ K++DFG+ Sbjct: 707 SFLRQNDGQFTVIQLVGMLR-GIAAGMKYLAEMNYVHRDLAARNILVNSNLVCKVSDFGL 765 Query: 1393 ARVEAQNPKDMTGATGTLG------YMAPEVLDGKPYNRKCDVYSFGICLWEVYCC-DMP 1551 +R + D T T +LG + APE + + + DV+S+GI +WEV + P Sbjct: 766 SRYLQDDTSDPT-YTSSLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGERP 824 Query: 1552 YPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 Y D+S DV +A + Q+ R P CP+A +M CW + + RP E+V ++ + Sbjct: 825 YWDMSNQDVINA-IEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKM 881
>Q91736:EPB1B_XENLA Ephrin type-B receptor 1-B - Xenopus laevis (African clawed frog)| Length = 902 Score = 113 bits (282), Expect = 4e-24 Identities = 81/298 (27%), Positives = 138/298 (46%), Gaps = 12/298 (4%) Frame = +1 Query: 868 EIDLAKLEIRHVIAQGTYGTVYRGTYDGQQ-----VAVKLLDWGEDGFATEAETTALRTS 1032 EID++ ++I VI G +G VY+G VA+K L G + R Sbjct: 531 EIDVSFVKIEEVIGAGEFGEVYKGRLKLPSKREISVAIKTLKAGY--------SEKQRRD 582 Query: 1033 FKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLK 1212 F E ++ + HPN+ + G +R ++ E++ G L Sbjct: 583 FLSEASIMGQFDHPNIIRLEGVVT------------------KSRPVMIITEFMENGALD 624 Query: 1213 QYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGV 1392 +L +N + ++V L ++ G+ YL VHRD+ N+L+++ K++DFG+ Sbjct: 625 SFLRQNDGQFTVIQLVGMLR-GIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGL 683 Query: 1393 ARVEAQNPKDMTGATGTLG------YMAPEVLDGKPYNRKCDVYSFGICLWEVYCC-DMP 1551 +R + D T T +LG + APE + + + DV+S+GI +WEV + P Sbjct: 684 SRYLQDDTSDPT-YTSSLGGKIPVRWTAPEAIRYRKFTSASDVWSYGIVMWEVMSYGERP 742 Query: 1552 YPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 Y D+S DV +A + Q+ R P CP+A +M CW + + RP E+V ++ + Sbjct: 743 YWDMSNQDVINA-IEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFGEIVNTLDKM 799
>P53667:LIMK1_HUMAN LIM domain kinase 1 - Homo sapiens (Human)| Length = 647 Score = 112 bits (281), Expect = 5e-24 Identities = 94/320 (29%), Positives = 142/320 (44%), Gaps = 26/320 (8%) Frame = +1 Query: 844 SLGPKADWEIDLAKLEIRHVIAQG---------TYGTVYRGTYDGQQVAVKLLDWGEDGF 996 SLG A DL + E V+ + +G V GQ + V + GE Sbjct: 307 SLGSPASQRKDLGRSESLRVVCRPHRIFRPSDLIHGEVLGKGCFGQAIKVTHRETGEVMV 366 Query: 997 ATEAETTALRT--SFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARA 1170 E T +F +EV V L HPNV KF+G L Sbjct: 367 MKELIRFDEETQRTFLKEVKVMRCLEHPNVLKFIGVLYKDKRLNF--------------- 411 Query: 1171 CCVVVEYLAGGTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENML 1350 + EY+ GGTL+ +IK+ + + V A D++ G++YLHS I+HRD+ + N L Sbjct: 412 ---ITEYIKGGTLRG-IIKSMDSQYPWSQRVSFAKDIASGMAYLHSMNIIHRDLNSHNCL 467 Query: 1351 LDTQRNLKIADFGVARV---EAQNPKDMTG-----------ATGTLGYMAPEVLDGKPYN 1488 + +N+ +ADFG+AR+ E P+ + G +MAPE+++G+ Y+ Sbjct: 468 VRENKNVVVADFGLARLMVDEKTQPEGLRSLKKPDRKKRYTVVGNPYWMAPEMINGRSYD 527 Query: 1489 RKCDVYSFGICLWEVYCCDMPYPDLSFADVSSAV-VHQNLRPDIPRCCPSAFANIMRKCW 1665 K DV+SFGI L E+ PD + + V L P CP +F I +C Sbjct: 528 EKVDVFSFGIVLCEIIGRVNADPDYLPRTMDFGLNVRGFLDRYCPPNCPPSFFPITVRCC 587 Query: 1666 DGNPDKRPDMDEVVQLMEAL 1725 D +P+KRP ++ +E L Sbjct: 588 DLDPEKRPSFVKLEHWLETL 607
>Q93105:INSR_AEDAE Insulin-like receptor precursor - Aedes aegypti (Yellowfever| mosquito) Length = 1390 Score = 112 bits (281), Expect = 5e-24 Identities = 81/302 (26%), Positives = 137/302 (45%), Gaps = 20/302 (6%) Frame = +1 Query: 862 DWEIDLAKLEIRHVIAQGTYGTVYRGTYD-------GQQVAVKLLDWGEDGFATEAETTA 1020 DWE++ + + QG++G VY+G Q A+K ++ E+ T Sbjct: 1017 DWEVERNHIIQLEELGQGSFGMVYKGILTQLRGEKCNQPCAIKTVN--------ESATAR 1068 Query: 1021 LRTSFKQEVAVWHKLSHPNVTKFVGA-SMGTTDLKIPVNDNGARANLPARACCVVVEYLA 1197 + SF E +V + + +V + +G S G L V++E +A Sbjct: 1069 EKDSFLLEASVMKQFNTHHVVRLLGVVSQGDPTL-------------------VIMELMA 1109 Query: 1198 GGTLKQYLIKNR---------RRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENML 1350 G LK YL ++R R+ + ++Q+A++++ G+ L ++K VHRD+ N + Sbjct: 1110 NGDLKSYLRRHRPDYEMRRSIRQPPTLRQIIQMAIEIADGIGVLSAKKFVHRDLAARNCM 1169 Query: 1351 LDTQRNLKIADFGVARVEAQNPKDMTGATGTL--GYMAPEVLDGKPYNRKCDVYSFGICL 1524 + +KI DFG+ R + G G L +MAPE L ++ DV+S+G+ L Sbjct: 1170 VADDMTVKIGDFGMTRDIYETDYYRKGTKGFLPVRWMAPESLKDGIFSSSSDVFSYGVVL 1229 Query: 1525 WEV-YCCDMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDE 1701 WE+ PY L+ V V+ + + P CP N+MR+CW P RP E Sbjct: 1230 WEMATLASQPYQGLTNDQVLRYVIDGGVM-ERPENCPDNLYNLMRRCWQHRPTARPTFME 1288 Query: 1702 VV 1707 ++ Sbjct: 1289 II 1290
>O35346:FAK1_RAT Focal adhesion kinase 1 - Rattus norvegicus (Rat)| Length = 1055 Score = 112 bits (281), Expect = 5e-24 Identities = 76/300 (25%), Positives = 139/300 (46%), Gaps = 8/300 (2%) Frame = +1 Query: 862 DWEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQ-----VAVKLLDWGEDGFATEAETTALR 1026 D+EI ++E+ I +G +G V++G Y + VA+K + ++R Sbjct: 414 DYEIQRERIELGRCIGEGQFGDVHQGVYLSPENPALAVAIKT--------CKNCTSDSVR 465 Query: 1027 TSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGT 1206 F QE + HP++ K +G + +++E G Sbjct: 466 EKFLQEALTMRQFDHPHIVKLIGV-------------------ITENPVWIIMELCTLGE 506 Query: 1207 LKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADF 1386 L+ +L + R+ L ++ A LS L+YL S++ VHRD+ N+L+ + +K+ DF Sbjct: 507 LRSFL-QVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDF 565 Query: 1387 GVAR-VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDM-PYPD 1560 G++R +E + + +MAPE ++ + + DV+ FG+C+WE+ + P+ Sbjct: 566 GLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQG 625 Query: 1561 LSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEV-VQLMEALDTSK 1737 + DV + + P P C P+ + ++M KCW +P +RP E+ QL L+ K Sbjct: 626 VKNNDVIGRIENGERLPMPPNCPPTLY-SLMTKCWAYDPSRRPRFTELKAQLSTILEEEK 684
>P34152:FAK1_MOUSE Focal adhesion kinase 1 - Mus musculus (Mouse)| Length = 1090 Score = 112 bits (281), Expect = 5e-24 Identities = 76/300 (25%), Positives = 139/300 (46%), Gaps = 8/300 (2%) Frame = +1 Query: 862 DWEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQ-----VAVKLLDWGEDGFATEAETTALR 1026 D+EI ++E+ I +G +G V++G Y + VA+K + ++R Sbjct: 452 DYEIQRERIELGRCIGEGQFGDVHQGVYLSPENPALAVAIKT--------CKNCTSDSVR 503 Query: 1027 TSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGT 1206 F QE + HP++ K +G + +++E G Sbjct: 504 EKFLQEALTMRQFDHPHIVKLIGV-------------------ITENPVWIIMELCTLGE 544 Query: 1207 LKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADF 1386 L+ +L + R+ L ++ A LS L+YL S++ VHRD+ N+L+ + +K+ DF Sbjct: 545 LRSFL-QVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDF 603 Query: 1387 GVAR-VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDM-PYPD 1560 G++R +E + + +MAPE ++ + + DV+ FG+C+WE+ + P+ Sbjct: 604 GLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQG 663 Query: 1561 LSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEV-VQLMEALDTSK 1737 + DV + + P P C P+ + ++M KCW +P +RP E+ QL L+ K Sbjct: 664 VKNNDVIGRIENGERLPMPPNCPPTLY-SLMTKCWAYDPSRRPRFTELKAQLSTILEEEK 722
>Q05397:FAK1_HUMAN Focal adhesion kinase 1 - Homo sapiens (Human)| Length = 1052 Score = 112 bits (281), Expect = 5e-24 Identities = 76/300 (25%), Positives = 139/300 (46%), Gaps = 8/300 (2%) Frame = +1 Query: 862 DWEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQ-----VAVKLLDWGEDGFATEAETTALR 1026 D+EI ++E+ I +G +G V++G Y + VA+K + ++R Sbjct: 414 DYEIQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKT--------CKNCTSDSVR 465 Query: 1027 TSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGT 1206 F QE + HP++ K +G + +++E G Sbjct: 466 EKFLQEALTMRQFDHPHIVKLIGV-------------------ITENPVWIIMELCTLGE 506 Query: 1207 LKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADF 1386 L+ +L + R+ L ++ A LS L+YL S++ VHRD+ N+L+ + +K+ DF Sbjct: 507 LRSFL-QVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDF 565 Query: 1387 GVAR-VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDM-PYPD 1560 G++R +E + + +MAPE ++ + + DV+ FG+C+WE+ + P+ Sbjct: 566 GLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQG 625 Query: 1561 LSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEV-VQLMEALDTSK 1737 + DV + + P P C P+ + ++M KCW +P +RP E+ QL L+ K Sbjct: 626 VKNNDVIGRIENGERLPMPPNCPPTLY-SLMTKCWAYDPSRRPRFTELKAQLSTILEEEK 684
>P17713:STK_HYDAT Tyrosine-protein kinase STK - Hydra attenuata (Hydra) (Hydra| vulgaris) Length = 509 Score = 112 bits (280), Expect = 6e-24 Identities = 83/291 (28%), Positives = 131/291 (45%), Gaps = 3/291 (1%) Frame = +1 Query: 856 KADWEIDLAKLEIRHVIAQGTYGTVYRGTYDGQ-QVAVKLLDWGEDGFATEAETTALRTS 1032 K WEI L + + G +G V+ G ++ QVAVK L G T S Sbjct: 230 KDAWEIPRESLRLNRKLGAGQFGEVWAGVWNNTTQVAVKTLKPG----------TMSPAS 279 Query: 1033 FKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLK 1212 F E V KL H ++ + + I V EY++GG+L Sbjct: 280 FLDEAGVMKKLRHKHLVQLYAICSDREPIYI------------------VTEYMSGGSLL 321 Query: 1213 QYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGV 1392 YL K L ++ +A ++ G+++L ++ +HRD+ N+L+ K+ADFG+ Sbjct: 322 DYLSKGEGVNLQLPTLIDMAAQVASGMAFLEAQGYIHRDLAARNILVGENYICKVADFGL 381 Query: 1393 AR-VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCD-MPYPDLS 1566 AR +E GA + + APE + K DV+SFGI + E+ +PYP ++ Sbjct: 382 ARLIEDDEYTAHEGAKFPIKWTAPEAALYNRFTIKSDVWSFGILMAEIVTKGRIPYPGMT 441 Query: 1567 FADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 1719 A + A V + R I CP NIM + W+ +P+ RP D + ++E Sbjct: 442 NAQ-TIAEVEKGYRMPIMPGCPEPLYNIMLQTWNKDPENRPTFDYLQGVLE 491
>P08922:ROS_HUMAN Proto-oncogene tyrosine-protein kinase ROS precursor - Homo sapiens| (Human) Length = 2347 Score = 112 bits (280), Expect = 6e-24 Identities = 93/295 (31%), Positives = 135/295 (45%), Gaps = 21/295 (7%) Frame = +1 Query: 883 KLEIRHVIAQGTYGTVYRGTY-------DGQ-QVAVKLLDWGEDGFATEAETTALRTSFK 1038 KL +R ++ G +G VY GT G+ +VAVK L G +T+ E + F Sbjct: 1944 KLTLRLLLGSGAFGEVYEGTAVDILGVGSGEIKVAVKTLKKG----STDQE----KIEFL 1995 Query: 1039 QEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQY 1218 +E + K +HPN+ K +G + N P +++E + GG L Y Sbjct: 1996 KEAHLMSKFNHPNILKQLGVCL---------------LNEPQY---IILELMEGGDLLTY 2037 Query: 1219 LIKNRRRK-----LAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQ-----RN 1368 L K R L +V L +D+S+G YL +HRD+ N L+ + R Sbjct: 2038 LRKARMATFYGPLLTLVDLVDLCVDISKGCVYLERMHFIHRDLAARNCLVSVKDYTSPRI 2097 Query: 1369 LKIADFGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEVYCC 1542 +KI DFG+AR +N G L +MAPE L + + DV+SFGI +WE+ Sbjct: 2098 VKIGDFGLARDIYKNDYYRKRGEGLLPVRWMAPESLMDGIFTTQSDVWSFGILIWEILTL 2157 Query: 1543 D-MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEV 1704 PYP S DV + V R + PR CP N+M +CW PD+RP + Sbjct: 2158 GHQPYPAHSNLDVLN-YVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRI 2211
>P25848:PHY1_CERPU Light-sensor Protein kinase [Includes: Phytochrome; Protein kinase -| Ceratodon purpureus (Moss) Length = 1307 Score = 112 bits (280), Expect = 6e-24 Identities = 95/359 (26%), Positives = 161/359 (44%), Gaps = 42/359 (11%) Frame = +1 Query: 775 DLTSLDIQLEQQLNKKWSKSNIKSLGPKADW----------EIDLAKLEIRHVIAQGTYG 924 D L I L Q+L + +K + S + W E ++I + G+ Sbjct: 959 DQNDLAIYLLQRLKR--AKPILPSFSSRPSWWNFYDDWSFSEKFFQWIQITGSLGSGSSA 1016 Query: 925 TVYRGTYDGQQVAVKLLDWGEDGFATEAETTALRTSFKQEVAVWHKLSHPNVTKFVGASM 1104 TV + + G VA K +G + FK+EV + +L HPN+T + Sbjct: 1017 TVEKAVWLGTPVAKKTF-YGRNN-----------EDFKREVEILAELCHPNITSMFCSP- 1063 Query: 1105 GTTDLKIPVNDNGARANLPARACCVVVEYLAGGTL---KQYLIKNRRRK---LAYKVVVQ 1266 L R C +++E + G L ++ L +N + VV Sbjct: 1064 -----------------LYRRKCSIIMELMDGDLLALMQRRLDRNEDHDSPPFSILEVVD 1106 Query: 1267 LALDLSRGLSYLHSRKIVHRDVKTENMLLDTQR---------NLKIADFGVARVEAQNPK 1419 + L S G++YLH + I+HRD+K+ N+L+ + + ++K+ADFG+++ + + + Sbjct: 1107 IILQTSEGMNYLHEKGIIHRDLKSMNILVKSVKVTKSEIGYVHVKVADFGLSKTKDSSTR 1166 Query: 1420 --DMTGATGTLGYMAPEVL-------------DGK--PYNRKCDVYSFGICLWEVYCCDM 1548 + T GT +MAPEV+ DGK Y K DVYSFG+ +EV D+ Sbjct: 1167 YSNQTWNRGTNRWMAPEVINLGYESTEGEISFDGKVPKYPLKSDVYSFGMVCYEVLTGDV 1226 Query: 1549 PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 P+P+ + +V + +RPD+P CP ++ CW+ +P KRP + Q ++ L Sbjct: 1227 PFPEEKNPNNVKRMVLEGVRPDLPAHCPIELKALITDCWNQDPLKRPSFAVICQKLKYL 1285
>P00538:MOS_MSVMO Serine/threonine-protein kinase-transforming protein mos - Moloney| murine sarcoma virus (MoMLV) Length = 374 Score = 112 bits (280), Expect = 6e-24 Identities = 91/313 (29%), Positives = 151/313 (48%), Gaps = 21/313 (6%) Frame = +1 Query: 865 WEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFATEAETTALRTSFKQE 1044 + ID ++ + H + G +G+VY+ TY G VA+K ++ TE + A + SF E Sbjct: 87 FSIDWEQVCLMHRLGSGGFGSVYKATYHGVPVAIKQVNK-----CTE-DLRASQRSFWAE 140 Query: 1045 VAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYLI 1224 + + L H N+ + V AS T P + N +++E+ TL Q + Sbjct: 141 LNI-AGLRHDNIVRVVAASTRT-----PEDSNSLGT--------IIMEFGGNVTLHQVIY 186 Query: 1225 K--------NRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIA 1380 + R++L+ ++ +LD+ GL +LHS+ I+H D+K N+L+ Q KI+ Sbjct: 187 DATRSPEPLSCRKQLSLGKCLKYSLDVVNGLLFLHSQSILHLDLKPANILISEQDVCKIS 246 Query: 1381 DFGVARVEAQNPKDMTGAT-------GTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYC 1539 DFG +Q +D+ G GT + APE+L G+ K D+YSFGI LW++ Sbjct: 247 DFGC----SQKLQDLRGRQASPPHIGGTYTHQAPEILKGEIATPKADIYSFGITLWQMTT 302 Query: 1540 CDMPYPDLSFADVSSAVVHQNLRPDI------PRCCPSAFANIMRKCWDGNPDKRPDMDE 1701 ++PY V AVV NLRP + A NI++ CW+ +RP + Sbjct: 303 REVPYSG-EPQYVQYAVVAYNLRPSLAGAVFTASLTGKALQNIIQSCWEARGLQRPSAEL 361 Query: 1702 VVQLMEALDTSKG 1740 + + ++A + G Sbjct: 362 LQRDLKAFRGTLG 374
>P00536:MOS_MOUSE Proto-oncogene serine/threonine-protein kinase mos - Mus musculus| (Mouse) Length = 390 Score = 112 bits (280), Expect = 6e-24 Identities = 85/287 (29%), Positives = 138/287 (48%), Gaps = 12/287 (4%) Frame = +1 Query: 865 WEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFATEAETTALRTSFKQE 1044 + ID ++ + H + G +G+VY+ TY G VA+K ++ + A + SF E Sbjct: 103 FSIDWEQVCLMHRLGSGGFGSVYKATYHGVPVAIKQVN------KCTKDLRASQRSFWAE 156 Query: 1045 VAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYLI 1224 + + +L H N+ + V AS T P + N + V + + G + Sbjct: 157 LNI-ARLRHDNIVRVVAASTRT-----PEDSNSLGTIIMEFGGNVTLHQVIYGATRSPEP 210 Query: 1225 KNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFG----- 1389 + R +L+ ++ +LD+ GL +LHS+ I+H D+K N+L+ Q KI+DFG Sbjct: 211 LSCREQLSLGKCLKYSLDVVNGLLFLHSQSILHLDLKPANILISEQDVCKISDFGCSQKL 270 Query: 1390 -VARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDMPYPDLS 1566 V R +P + GT + APE+L G+ K D+YSFGI LW++ ++PY Sbjct: 271 QVLRCRQASPHHI---GGTYTHQAPEILKGEIATPKADIYSFGITLWQMTTREVPYSG-E 326 Query: 1567 FADVSSAVVHQNLRPDIPRCCPSA------FANIMRKCWDGNPDKRP 1689 V AVV NLRP + +A NI++ CW+ +RP Sbjct: 327 PQYVQYAVVAYNLRPSLAGAVFTASLTGKTLQNIIQSCWEARALQRP 373
>O73798:IGF1R_XENLA Insulin-like growth factor 1 receptor precursor - Xenopus laevis| (African clawed frog) Length = 1358 Score = 112 bits (280), Expect = 6e-24 Identities = 84/300 (28%), Positives = 134/300 (44%), Gaps = 19/300 (6%) Frame = +1 Query: 865 WEIDLAKLEIRHVIAQGTYGTVYRGTYDG-------QQVAVKLLDWGEDGFATEAETTAL 1023 WE+ K+ + + QG++G VY G G +VA+K ++ EA + Sbjct: 988 WEVPREKITMNRELGQGSFGMVYEGIAKGVVKDEAETKVAIKTVN--------EAASMRE 1039 Query: 1024 RTSFKQEVAVWHKLSHPNVTKFVGA-SMGTTDLKIPVNDNGARANLPARACCVVVEYLAG 1200 R F E +V + + +V + +G S G L V++E + Sbjct: 1040 RIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTL-------------------VIMELMTR 1080 Query: 1201 GTLKQYLIKNR--------RRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLD 1356 G LK YL R + + K ++Q+A +++ G+SYL++ K VHRD+ N ++ Sbjct: 1081 GDLKSYLRSLRPDTESNSGQPTPSLKKMIQMAGEIADGMSYLNANKFVHRDLAARNCMVT 1140 Query: 1357 TQRNLKIADFGVARVEAQNPKDMTGATGTL--GYMAPEVLDGKPYNRKCDVYSFGICLWE 1530 +KI DFG+ R + G G L +M+PE L + DV+SFG+ LWE Sbjct: 1141 EDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTNSDVWSFGVVLWE 1200 Query: 1531 V-YCCDMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVV 1707 + + PY +S V V+ L + P CP +MR CW NP RP E++ Sbjct: 1201 IATLAEQPYQGMSNEQVLRFVMEGGLL-EKPDNCPDMLFELMRMCWQFNPKMRPSFLEII 1259
>P24062:IGF1R_RAT Insulin-like growth factor 1 receptor precursor - Rattus norvegicus| (Rat) Length = 1370 Score = 112 bits (280), Expect = 6e-24 Identities = 85/302 (28%), Positives = 137/302 (45%), Gaps = 20/302 (6%) Frame = +1 Query: 862 DWEIDLAKLEIRHVIAQGTYGTVYRGTYDG-------QQVAVKLLDWGEDGFATEAETTA 1020 +WE+ K+ + + QG++G VY G G +VA+K ++ EA + Sbjct: 992 EWEVAREKITMNRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVN--------EAASMR 1043 Query: 1021 LRTSFKQEVAVWHKLSHPNVTKFVGA-SMGTTDLKIPVNDNGARANLPARACCVVVEYLA 1197 R F E +V + + +V + +G S G L V++E + Sbjct: 1044 ERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTL-------------------VIMELMT 1084 Query: 1198 GGTLKQYLIKNRRRKLAYKVV---------VQLALDLSRGLSYLHSRKIVHRDVKTENML 1350 G LK YL ++ R ++ +V +Q+A +++ G++YL++ K VHRD+ N + Sbjct: 1085 RGDLKSYL-RSLRPEVENNLVLIPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCM 1143 Query: 1351 LDTQRNLKIADFGVARVEAQNPKDMTGATGTL--GYMAPEVLDGKPYNRKCDVYSFGICL 1524 + +KI DFG+ R + G G L +M+PE L + DV+SFG+ L Sbjct: 1144 VAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGVVL 1203 Query: 1525 WEV-YCCDMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDE 1701 WE+ + PY LS V V+ L D P CP +MR CW NP RP E Sbjct: 1204 WEIATLAEQPYQGLSNEQVLRFVMEGGLL-DKPDNCPDMLFELMRMCWQYNPKMRPSFLE 1262 Query: 1702 VV 1707 ++ Sbjct: 1263 II 1264
>P13406:FYN_XENLA Proto-oncogene tyrosine-protein kinase Fyn - Xenopus laevis (African| clawed frog) Length = 537 Score = 112 bits (280), Expect = 6e-24 Identities = 82/295 (27%), Positives = 136/295 (46%), Gaps = 3/295 (1%) Frame = +1 Query: 844 SLGPKADWEIDLAKLEIRHVIAQGTYGTVYRGTYDGQ-QVAVKLLDWGEDGFATEAETTA 1020 S+ K WEI L++ + G +G V+ GT++G +VA+K L G T Sbjct: 257 SVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNGNTKVAIKTLKPG----------TM 306 Query: 1021 LRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAG 1200 SF +E + KL H + + A + +V EY++ Sbjct: 307 SPESFLEEAQIMKKLKHDKLVQLY-------------------AVVSEEPIYIVTEYMSK 347 Query: 1201 GTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIA 1380 G+L +L R L +V +A ++RG++Y+ +HRD+++ N+L+ KIA Sbjct: 348 GSLLDFLKDGEGRALKLPNLVDMAAQVARGMAYIERMNYIHRDLRSANILVGNGLICKIA 407 Query: 1381 DFGVAR-VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCD-MPY 1554 DFG+AR +E GA + + APE + K DV+SFGI L E+ +PY Sbjct: 408 DFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPY 467 Query: 1555 PDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 1719 P ++ +V V + R P+ CP + +M CW +P++RP + + +E Sbjct: 468 PGMNNREVLEQ-VERGYRMPCPQDCPISLHELMLNCWKKDPEERPTFEYLQGFLE 521
>Q91738:FAK1_XENLA Focal adhesion kinase 1 - Xenopus laevis (African clawed frog)| Length = 1068 Score = 112 bits (280), Expect = 6e-24 Identities = 76/305 (24%), Positives = 140/305 (45%), Gaps = 8/305 (2%) Frame = +1 Query: 847 LGPKADWEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQ-----VAVKLLDWGEDGFATEAE 1011 L D+EI ++E+ I +G +G V++G Y + VA+K Sbjct: 422 LDEAGDYEIQRDRIELGRCIGEGQFGDVHQGVYMSPENPAMAVAIKT--------CKNCT 473 Query: 1012 TTALRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEY 1191 + ++R F QE + HP++ K +G + +++E Sbjct: 474 SDSVREKFLQEALTMRQFDHPHIVKLIGV-------------------ITENPVWIIMEL 514 Query: 1192 LAGGTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNL 1371 G L+ +L + R+ L ++ + LS L+YL S++ VHRD+ N+L+ + + Sbjct: 515 CTLGELRSFL-QVRKYSLDLASLILYSYQLSTALAYLESKRFVHRDIAARNVLVSSSDCV 573 Query: 1372 KIADFGVAR-VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDM 1548 K+ DFG++R +E + + +MAPE ++ + + DV+ FG+C+WE+ + Sbjct: 574 KLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMYGV 633 Query: 1549 -PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEV-VQLMEA 1722 P+ + DV + + P P C P+ + ++M KCW +P +RP E+ QL Sbjct: 634 KPFQGVKNNDVIGRIENGERLPMPPNCPPTLY-SLMTKCWAYDPSRRPRFTELKAQLSTI 692 Query: 1723 LDTSK 1737 L+ K Sbjct: 693 LEEEK 697
>O13147:EPHB3_DANRE Ephrin type-B receptor 3 - Danio rerio (Zebrafish) (Brachydanio| rerio) Length = 500 Score = 112 bits (280), Expect = 6e-24 Identities = 91/319 (28%), Positives = 143/319 (44%), Gaps = 14/319 (4%) Frame = +1 Query: 868 EIDLAKLEIRHVIAQGTYGTVYRGTYD--GQQ---VAVKLLDWGEDGFATEAETTALRTS 1032 EID++ ++I VI G +G V RG G++ VA+K L G T R Sbjct: 181 EIDISCVKIEEVIGAGEFGEVCRGRLKQAGRKETTVAIKTLKAGY--------TEHQRRD 232 Query: 1033 FKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARAC--CVVVEYLAGGT 1206 F E ++ + HPNV G R+C +V E++ G Sbjct: 233 FLSEASIMGQFDHPNVIHLEGVL--------------------TRSCPVLIVTEFMENGA 272 Query: 1207 LKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADF 1386 L +L N R ++V L ++ G+ YL VHRD+ N+L+++ K++DF Sbjct: 273 LDSFLRLNDGRFTVTQLVGMLR-GIAAGMKYLSDMNYVHRDLAARNVLVNSNLVCKVSDF 331 Query: 1387 GVARVEAQNPKDMTGATGTLG------YMAPEVLDGKPYNRKCDVYSFGICLWEVYCC-D 1545 G++R N D T T +LG + APE + + + DV+S+GI +WEV + Sbjct: 332 GLSRFLDDNSSDPT-YTSSLGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVMSFGE 390 Query: 1546 MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 PY D+S DV +A V Q+ R P CP+ +M +CW + RP ++V ++ Sbjct: 391 RPYWDMSNQDVMNA-VEQDYRLPPPMDCPAVLHQLMLECWVKERNMRPRFGQIVSTLDKF 449 Query: 1726 DTSKGGGMIPDGQSSGCLC 1782 + + SG LC Sbjct: 450 LRNAASLKVLTSTHSGDLC 468
>Q63132:ROS_RAT Proto-oncogene tyrosine-protein kinase ROS precursor - Rattus| norvegicus (Rat) Length = 2338 Score = 112 bits (279), Expect = 8e-24 Identities = 91/290 (31%), Positives = 136/290 (46%), Gaps = 21/290 (7%) Frame = +1 Query: 883 KLEIRHVIAQGTYGTVYRGTY-------DGQ-QVAVKLLDWGEDGFATEAETTALRTSFK 1038 KL +R ++ G +G VY GT G+ +VAVK L G +T+ E + F Sbjct: 1936 KLSLRLLLGSGAFGEVYEGTAVDILGRGSGEIKVAVKTLKKG----STDQE----KIEFL 1987 Query: 1039 QEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQY 1218 +E + K +HPN+ K +G L + +++E + GG L Y Sbjct: 1988 KEAHLMSKFNHPNILKQLGVC------------------LLSEPQYIILELMEGGDLLSY 2029 Query: 1219 LIKNRRRKLAYKVV-----VQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQ-----RN 1368 L K R L+ ++ V+L +D+S+G YL +HRD+ N L+ + R Sbjct: 2030 LRKARGTTLSGPLLTLADLVELCVDISKGCVYLEQMHFIHRDLAARNCLVSVKDYTSPRV 2089 Query: 1369 LKIADFGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEVYCC 1542 +KI DFG+AR ++ G L +MAPE L + + DV+SFGI +WE+ Sbjct: 2090 VKIGDFGLAREIYKHDYYRKRGEGLLPVRWMAPENLMDGIFTSQSDVWSFGILVWEILTL 2149 Query: 1543 D-MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRP 1689 PYP S DV + V R + PR CP N+M +CW PD+RP Sbjct: 2150 GHQPYPAHSNLDVLN-YVQAGGRLEPPRNCPDDLWNLMFRCWAQEPDQRP 2198
>Q08881:ITK_HUMAN Tyrosine-protein kinase ITK/TSK - Homo sapiens (Human)| Length = 620 Score = 112 bits (279), Expect = 8e-24 Identities = 81/295 (27%), Positives = 140/295 (47%), Gaps = 6/295 (2%) Frame = +1 Query: 865 WEIDLAKLEIRHVIAQGTYGTVYRGTY-DGQQVAVKLLDWGEDGFATEAETTALRTSFKQ 1041 W ID ++L I G +G V+ G + + +VA+K + +G +E + F + Sbjct: 356 WVIDPSELTFVQEIGSGQFGLVHLGYWLNKDKVAIKTI---REGAMSEED-------FIE 405 Query: 1042 EVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYL 1221 E V KLSHP + + G + + C+V E++ G L YL Sbjct: 406 EAEVMMKLSHPKLVQLYGVCLEQAPI------------------CLVFEFMEHGCLSDYL 447 Query: 1222 IKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGVARV 1401 + +R A + ++ + LD+ G++YL ++HRD+ N L+ + +K++DFG+ R Sbjct: 448 -RTQRGLFAAETLLGMCLDVCEGMAYLEEACVIHRDLAARNCLVGENQVIKVSDFGMTRF 506 Query: 1402 EAQNPKDMTGATGT---LGYMAPEVLDGKPYNRKCDVYSFGICLWEVYC-CDMPYPDLSF 1569 + T +TGT + + +PEV Y+ K DV+SFG+ +WEV+ +PY + S Sbjct: 507 VLDD--QYTSSTGTKFPVKWASPEVFSFSRYSSKSDVWSFGVLMWEVFSEGKIPYENRSN 564 Query: 1570 ADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVV-QLMEALDT 1731 ++V + R PR + IM CW P+ RP ++ QL E ++ Sbjct: 565 SEVVED-ISTGFRLYKPRLASTHVYQIMNHCWKERPEDRPAFSRLLRQLAEIAES 618
>P50545:HCK_RAT Tyrosine-protein kinase HCK - Rattus norvegicus (Rat)| Length = 524 Score = 112 bits (279), Expect = 8e-24 Identities = 80/296 (27%), Positives = 133/296 (44%), Gaps = 3/296 (1%) Frame = +1 Query: 856 KADWEIDLAKLEIRHVIAQGTYGTVYRGTYDGQ-QVAVKLLDWGEDGFATEAETTALRTS 1032 K WEI L++ + G +G V+ TY+ +VAVK + G + EA Sbjct: 250 KDAWEIPRESLQMEKKLGAGQFGEVWMATYNKHTKVAVKTMKPGS--MSVEA-------- 299 Query: 1033 FKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLK 1212 F E + L H + K A + +V E++A G+L Sbjct: 300 FLAEANLMKTLQHDKLVKL-------------------HAVVSQEPIFIVTEFMAKGSLL 340 Query: 1213 QYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGV 1392 +L K ++ + +S G++++ R +HRD++ N+L+ KIADFG+ Sbjct: 341 DFLKSEEGSKQPLPKLIDFSAQISEGMAFIEQRNYIHRDLRAANILVSASLVCKIADFGL 400 Query: 1393 ARVEAQNP-KDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCD-MPYPDLS 1566 AR+ N GA + + APE ++ + K DV+SFGI L E+ +PYP +S Sbjct: 401 ARIIEDNEYTAREGAKFPIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMS 460 Query: 1567 FADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDTS 1734 +V A+ H R P CP +IM +CW P++RP + + +++ T+ Sbjct: 461 NPEVIRALEH-GYRMPRPDNCPEELYSIMIRCWKNRPEERPTFEYIQSVLDDFYTA 515
>P27446:FYN_XIPHE Proto-oncogene tyrosine-protein kinase FYN - Xiphophorus helleri| Length = 537 Score = 112 bits (279), Expect = 8e-24 Identities = 82/295 (27%), Positives = 137/295 (46%), Gaps = 3/295 (1%) Frame = +1 Query: 844 SLGPKADWEIDLAKLEIRHVIAQGTYGTVYRGTYDGQ-QVAVKLLDWGEDGFATEAETTA 1020 S+ K WEI L++ + G +G V+ GT++G +VAVK L G T Sbjct: 257 SVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNGTTKVAVKTLKPG----------TM 306 Query: 1021 LRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAG 1200 SF +E + KL H + + A + +V EY++ Sbjct: 307 SPESFLEEAQIMKKLRHDKLVQLY-------------------AVVSEEPIYIVTEYMSK 347 Query: 1201 GTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIA 1380 G+L +L R L +V +A ++ G++Y+ +HRD+++ N+L+ KIA Sbjct: 348 GSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGDNLVCKIA 407 Query: 1381 DFGVAR-VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCD-MPY 1554 DFG+AR +E GA + + APE + K DV+SFGI L E+ +PY Sbjct: 408 DFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPY 467 Query: 1555 PDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 1719 P ++ +V V + R P+ CP++ +M +CW +P++RP + + +E Sbjct: 468 PGMNNREVLEQ-VERGYRMPCPQDCPASLHELMLQCWKKDPEERPTFEYLQAFLE 521
>P07331:MOS_MSVMH Serine/threonine-protein kinase-transforming protein mos - Moloney| murine sarcoma virus (strain HT-1) Length = 374 Score = 111 bits (278), Expect = 1e-23 Identities = 86/304 (28%), Positives = 146/304 (48%), Gaps = 12/304 (3%) Frame = +1 Query: 865 WEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFATEAETTALRTSFKQE 1044 + ID ++ + H + G +G+VY+ TY G VA+K ++ + A + SF E Sbjct: 87 FSIDWEQVCLMHRLGSGGFGSVYKATYHGVPVAIKQVN------KCTKDLRASQRSFWAE 140 Query: 1045 VAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYLI 1224 + + +L H N+ + V AS T P + N + V + + G + Sbjct: 141 LNI-ARLRHDNIVRVVAASTRT-----PEDSNSLGTIIMEFGGNVTLHQVIYGATRSPEP 194 Query: 1225 KNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGVA--- 1395 + R +L+ ++ +LD+ GL +LHS+ I+H D+K N+L+ Q KI+DFG + Sbjct: 195 LSCREQLSLGKCLKYSLDVVNGLLFLHSQSILHLDLKPANILISEQDVCKISDFGCSQKL 254 Query: 1396 ---RVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDMPYPDLS 1566 R +P + GT + APE+L G+ K D+YSFGI LW++ ++PY Sbjct: 255 QDLRCRQASPHHI---GGTYTHQAPEILKGEIATPKADIYSFGITLWQMTTREVPYSG-E 310 Query: 1567 FADVSSAVVHQNLRPDIPRCCPSA------FANIMRKCWDGNPDKRPDMDEVVQLMEALD 1728 V AVV NLRP + +A NI++ CW+ +RP + + + ++A Sbjct: 311 PQYVQYAVVAYNLRPSLAGAVFTASLTGKTLQNIIQSCWEARALQRPGAELLQRDLKAFR 370 Query: 1729 TSKG 1740 + G Sbjct: 371 GALG 374
>Q60751:IGF1R_MOUSE Insulin-like growth factor 1 receptor precursor - Mus musculus| (Mouse) Length = 1373 Score = 111 bits (278), Expect = 1e-23 Identities = 85/302 (28%), Positives = 133/302 (44%), Gaps = 20/302 (6%) Frame = +1 Query: 862 DWEIDLAKLEIRHVIAQGTYGTVYRGTYDG-------QQVAVKLLDWGEDGFATEAETTA 1020 +WE+ K+ + + QG++G VY G G +VA+K ++ EA + Sbjct: 992 EWEVAREKITMNRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVN--------EAASMR 1043 Query: 1021 LRTSFKQEVAVWHKLSHPNVTKFVGA-SMGTTDLKIPVNDNGARANLPARACCVVVEYLA 1197 R F E +V + + +V + +G S G L V++E + Sbjct: 1044 ERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTL-------------------VIMELMT 1084 Query: 1198 GGTLKQYLIKNRRRKLAYKVV---------VQLALDLSRGLSYLHSRKIVHRDVKTENML 1350 G LK YL R +V +Q+A +++ G++YL++ K VHRD+ N + Sbjct: 1085 RGDLKSYLRSLRPEVEQNNLVLIPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCM 1144 Query: 1351 LDTQRNLKIADFGVARVEAQNPKDMTGATGTL--GYMAPEVLDGKPYNRKCDVYSFGICL 1524 + +KI DFG+ R + G G L +M+PE L + DV+SFG+ L Sbjct: 1145 VAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGVVL 1204 Query: 1525 WEV-YCCDMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDE 1701 WE+ + PY LS V V+ L D P CP +MR CW NP RP E Sbjct: 1205 WEIATLAEQPYQGLSNEQVLRFVMEGGLL-DKPDNCPDMLFELMRMCWQYNPKMRPSFLE 1263 Query: 1702 VV 1707 ++ Sbjct: 1264 II 1265
>P18460:FGFR3_CHICK Fibroblast growth factor receptor 3 precursor - Gallus gallus| (Chicken) Length = 806 Score = 111 bits (278), Expect = 1e-23 Identities = 89/322 (27%), Positives = 146/322 (45%), Gaps = 27/322 (8%) Frame = +1 Query: 847 LGPKADWEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQ---------VAVKLLDWGEDGFA 999 L P WE+ ++L + + +G +G V G VAVK+L +D A Sbjct: 453 LPPDPKWELARSRLTLGKPLGEGCFGQVVMAEAIGIDKDKPNKAITVAVKMLK--DD--A 508 Query: 1000 TEAETTALRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCV 1179 T+ + + L + + + H N+ +GA L V Sbjct: 509 TDKDLSDLVSEMEMMKMIG---KHKNIINLLGACTQDGPLY------------------V 547 Query: 1180 VVEYLAGGTLKQYLIKNR--------------RRKLAYKVVVQLALDLSRGLSYLHSRKI 1317 +VEY + G L++YL R +L +K +V A ++RG+ YL S+K Sbjct: 548 LVEYASKGNLREYLRARRPPGMDYSFDTCKLPEEQLTFKDLVSCAYQVARGMEYLASQKC 607 Query: 1318 VHRDVKTENMLLDTQRNLKIADFGVARVEAQN---PKDMTGATGTLGYMAPEVLDGKPYN 1488 +HRD+ N+L+ +KIADFG+AR + N K T + +MAPE L + Y Sbjct: 608 IHRDLAARNVLVTEDNVMKIADFGLAR-DVHNIDYYKKTTNGRLPVKWMAPEALFDRVYT 666 Query: 1489 RKCDVYSFGICLWEVYCC-DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCW 1665 + DV+SFG+ LWE++ PYP + ++ ++ + R D P C IMR+CW Sbjct: 667 HQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFK-LLKEGHRMDKPANCTHDLYMIMRECW 725 Query: 1666 DGNPDKRPDMDEVVQLMEALDT 1731 P +RP ++V+ ++ + T Sbjct: 726 HAVPSQRPTFKQLVEDLDRVLT 747
>Q00944:FAK1_CHICK Focal adhesion kinase 1 - Gallus gallus (Chicken)| Length = 1053 Score = 111 bits (278), Expect = 1e-23 Identities = 76/300 (25%), Positives = 138/300 (46%), Gaps = 8/300 (2%) Frame = +1 Query: 862 DWEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQ-----VAVKLLDWGEDGFATEAETTALR 1026 D+EI ++E+ I +G +G V++G Y + VA+K + ++R Sbjct: 414 DYEIQRERIELGRCIGEGQFGDVHQGIYMSPENPAMAVAIKT--------CKNCTSDSVR 465 Query: 1027 TSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGT 1206 F QE + HP++ K +G + +++E G Sbjct: 466 EKFLQEALTMRQFDHPHIVKLIGV-------------------ITENPVWIIMELCTLGE 506 Query: 1207 LKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADF 1386 L+ +L + R+ L ++ A LS L+YL S++ VHRD+ N+L+ +K+ DF Sbjct: 507 LRSFL-QVRKFSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSATDCVKLGDF 565 Query: 1387 GVAR-VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDM-PYPD 1560 G++R +E + + +MAPE ++ + + DV+ FG+C+WE+ + P+ Sbjct: 566 GLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQG 625 Query: 1561 LSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEV-VQLMEALDTSK 1737 + DV + + P P C P+ + ++M KCW +P +RP E+ QL L+ K Sbjct: 626 VKNNDVIGRIENGERLPMPPNCPPTLY-SLMTKCWAYDPSRRPRFTELKAQLSTILEEEK 684
>P54755:EPHA5_CHICK Ephrin type-A receptor 5 precursor - Gallus gallus (Chicken)| Length = 1013 Score = 111 bits (278), Expect = 1e-23 Identities = 81/295 (27%), Positives = 134/295 (45%), Gaps = 9/295 (3%) Frame = +1 Query: 868 EIDLAKLEIRHVIAQGTYGTVYRGTYDGQ-----QVAVKLLDWGEDGFATEAETTALRTS 1032 EI+ + + I VI G +G V G Q VA+K L G T R Sbjct: 645 EIEASCITIERVIGAGEFGEVCSGRLKLQGKREFPVAIKTLKVGY--------TEKQRRD 696 Query: 1033 FKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLK 1212 F E ++ + HPN+ G ++ +V EY+ G+L Sbjct: 697 FLGEASIMGQFDHPNIIHLEGVVT------------------KSKPVMIVTEYMENGSLD 738 Query: 1213 QYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGV 1392 +L KN + ++V L ++ G+ YL VHRD+ N+L+++ K++DFG+ Sbjct: 739 TFLKKNDGQFTVIQLVGMLR-GIASGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGL 797 Query: 1393 ARVEAQNPK---DMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCC-DMPYPD 1560 +RV +P+ G + + APE + + + DV+S+GI +WEV + PY + Sbjct: 798 SRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVMSYGERPYWE 857 Query: 1561 LSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 ++ DV A V + R P CP+A +M CW + + RP DE+V +++ L Sbjct: 858 MTNQDVIKA-VEEGYRLPSPMDCPAALYQLMLDCWQKDRNSRPKFDEIVSMLDKL 911
>P42682:TXK_MOUSE Tyrosine-protein kinase TXK - Mus musculus (Mouse)| Length = 527 Score = 111 bits (277), Expect = 1e-23 Identities = 81/287 (28%), Positives = 133/287 (46%), Gaps = 3/287 (1%) Frame = +1 Query: 865 WEIDLAKLEIRHVIAQGTYGTVYRGTYDGQ-QVAVKLLDWGEDGFATEAETTALRTSFKQ 1041 WEID ++L I G +G V+ G + VA+K ++ +G +E + F + Sbjct: 264 WEIDPSELAFVKEIGSGQFGVVHLGEWRAHIPVAIKAIN---EGSMSEED-------FIE 313 Query: 1042 EVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYL 1221 E V KLSH + + G + L I V E++ G L YL Sbjct: 314 EAKVMMKLSHSRLVQLYGVCIQQKPLYI------------------VTEFMENGCLLDYL 355 Query: 1222 IKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGVARV 1401 + R+ +L +++ + D+ G++YL +HRD+ N L+ + +KI+DFG+AR Sbjct: 356 -RERKGQLQKALLLSMCQDICEGMAYLERSCYIHRDLAARNCLVSSACVVKISDFGMARY 414 Query: 1402 EAQNPK-DMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYC-CDMPYPDLSFAD 1575 + +GA + + PEV Y+ K DV+SFG+ +WEV+ MP+ + S Sbjct: 415 VLDDEYISSSGAKFPVKWCPPEVFHFNKYSSKSDVWSFGVLMWEVFTEGKMPFENKSNLQ 474 Query: 1576 VSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLM 1716 V A + Q R P P +M CW +P RP E++Q++ Sbjct: 475 VVEA-ISQGFRLYRPHLAPMTIYRVMYSCWHESPKGRPTFAELLQVL 520
>P10421:MOS_MSVTS Serine/threonine-protein kinase-transforming protein mos -| Myeloproliferative sarcoma virus (isolate ts159) Length = 342 Score = 111 bits (277), Expect = 1e-23 Identities = 84/300 (28%), Positives = 146/300 (48%), Gaps = 8/300 (2%) Frame = +1 Query: 865 WEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFATEAETTALRTSFKQE 1044 + ID ++ + H + G +G+VY+ TY G VA+K ++ + A + SF E Sbjct: 56 FSIDWEQVCLMHRLGSGGFGSVYKATYHGVPVAIKQVN------KCTKDLRASQRSFWAE 109 Query: 1045 VAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYLI 1224 + + +L H N+ + V AS T P + N + V + + G + Sbjct: 110 LNI-ARLRHDNIVRVVAASTRT-----PEDSNSLGTIIMEFGGNVTLHQVIYGATRSPEP 163 Query: 1225 KNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGVAR-- 1398 + R +L+ ++ +LD+ GL +LHS+ I+H D+K N+L+ Q KI+DFG ++ Sbjct: 164 LSCREQLSLGKCLKYSLDVVNGLLFLHSQSILHLDLKPANILISEQDVCKISDFGCSQKL 223 Query: 1399 VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDMPYPDLSFADV 1578 + + + GT + APE+L G+ K D+YSFGI LW++ ++PY V Sbjct: 224 QDLRCRQSPHHIGGTYTHQAPEILKGEIATPKADIYSFGITLWQMTTREVPYSG-EPQYV 282 Query: 1579 SSAVVHQNLRPDIPRCCPSA------FANIMRKCWDGNPDKRPDMDEVVQLMEALDTSKG 1740 AVV NLRP + +A NI++ CW+ +RP + + + ++A + G Sbjct: 283 QYAVVAYNLRPSLTGAVFTASLTRKTLQNIIQNCWEARALQRPGAELLQRDLKAFRGALG 342
>P29376:LTK_HUMAN Leukocyte tyrosine kinase receptor precursor - Homo sapiens (Human)| Length = 864 Score = 111 bits (277), Expect = 1e-23 Identities = 89/316 (28%), Positives = 133/316 (42%), Gaps = 25/316 (7%) Frame = +1 Query: 847 LGPKADW-------EIDLAKLEIRHVIAQGTYGTVYRGTYDGQ-------QVAVKLLDWG 984 LGP W E+ A + + + G +G VY G G QVA+K L Sbjct: 490 LGPAQSWPLPPGVTEVSPANVTLLRALGHGAFGEVYEGLVIGLPGDSSPLQVAIKTLP-- 547 Query: 985 EDGFATEAETTALRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPA 1164 E + F E + K H N+ + VG S+ T I Sbjct: 548 ------ELCSPQDELDFLMEALIISKFRHQNIVRCVGLSLRATPRLI------------- 588 Query: 1165 RACCVVVEYLAGGTLKQYLIKNRRR-----KLAYKVVVQLALDLSRGLSYLHSRKIVHRD 1329 ++E ++GG +K +L +R L + ++QLA D+++G YL +HRD Sbjct: 589 -----LLELMSGGDMKSFLRHSRPHLGQPSPLVMRDLLQLAQDIAQGCHYLEENHFIHRD 643 Query: 1330 VKTENMLLD---TQRNLKIADFGVAR--VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRK 1494 + N LL R KI DFG+AR A + A + +M PE + K Sbjct: 644 IAARNCLLSCAGPSRVAKIGDFGMARDIYRASYYRRGDRALLPVKWMPPEAFLEGIFTSK 703 Query: 1495 CDVYSFGICLWEVYCCD-MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDG 1671 D +SFG+ LWE++ MPYP + +V VV R D PR CP IM +CW Sbjct: 704 TDSWSFGVLLWEIFSLGYMPYPGRTNQEVLDFVVGGG-RMDPPRGCPGPVYRIMTQCWQH 762 Query: 1672 NPDKRPDMDEVVQLME 1719 P+ RP +++ ++ Sbjct: 763 EPELRPSFASILERLQ 778
>Q05688:IGF1R_BOVIN Insulin-like growth factor 1 receptor precursor - Bos taurus (Bovine)| Length = 640 Score = 111 bits (277), Expect = 1e-23 Identities = 85/301 (28%), Positives = 133/301 (44%), Gaps = 19/301 (6%) Frame = +1 Query: 862 DWEIDLAKLEIRHVIAQGTYGTVYRGTYDG-------QQVAVKLLDWGEDGFATEAETTA 1020 +WE+ K+ + + QG++G VY G G +VA+K ++ EA + Sbjct: 264 EWEVAREKITMSRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVN--------EAASMR 315 Query: 1021 LRTSFKQEVAVWHKLSHPNVTKFVGA-SMGTTDLKIPVNDNGARANLPARACCVVVEYLA 1197 R F E +V + + +V + +G S G L V++E + Sbjct: 316 ERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTL-------------------VIMELMT 356 Query: 1198 GGTLKQYLIKNRRRKLAYKVV--------VQLALDLSRGLSYLHSRKIVHRDVKTENMLL 1353 G LK YL R V+ +Q+A +++ G++YL++ K VHRD+ N ++ Sbjct: 357 RGDLKSYLRSLRPEMENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMV 416 Query: 1354 DTQRNLKIADFGVARVEAQNPKDMTGATGTL--GYMAPEVLDGKPYNRKCDVYSFGICLW 1527 +KI DFG+ R + G G L +M+PE L + DV+SFG+ LW Sbjct: 417 AEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGVVLW 476 Query: 1528 EV-YCCDMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEV 1704 E+ + PY LS V V+ L D P CP +MR CW NP RP E+ Sbjct: 477 EIATLAEQPYQGLSNEQVLRFVMEGGLL-DKPDNCPDMLFELMRMCWQYNPKMRPSFLEI 535 Query: 1705 V 1707 + Sbjct: 536 I 536
>Q91285:FGFR1_PLEWA Fibroblast growth factor receptor 1 precursor - Pleurodeles waltlii| (Iberian ribbed newt) Length = 816 Score = 111 bits (277), Expect = 1e-23 Identities = 96/344 (27%), Positives = 150/344 (43%), Gaps = 40/344 (11%) Frame = +1 Query: 865 WEIDLAKLEIRHVIAQGTYGTVYRGTYDG---------QQVAVKLLDWGEDGFATEAETT 1017 WE +L + + +G +G V G G +VAVK+L ATE + + Sbjct: 467 WEFSRDRLILGKPLGEGCFGQVVMGEAIGLDKEKPNRVTKVAVKMLK----SDATEKDLS 522 Query: 1018 ALRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLA 1197 L + + + H N+ +GA L V+VEY + Sbjct: 523 DLISEMEMMKMIG---KHKNIINLLGACTQDGPLY------------------VIVEYAS 561 Query: 1198 GGTLKQYLIKNR--------------RRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVK 1335 G L++YL R + L++K +V A ++RG+ YL S+K +HRD+ Sbjct: 562 KGNLREYLRARRPPGMEYCYNPIHVSKDMLSFKDLVSCAYQVARGMEYLASKKCIHRDLA 621 Query: 1336 TENMLLDTQRNLKIADFGVAR--VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYS 1509 N+L+ +KIADFG+AR K T + +MAPE L + Y + DV+S Sbjct: 622 ARNVLVTEDSVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWS 681 Query: 1510 FGICLWEVYCC-DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKR 1686 FG+ LWE++ PYP + ++ ++ + R D P C + +MR CW P +R Sbjct: 682 FGVLLWEIFTLGGSPYPGVPVEELFK-LLKEGHRMDKPGNCTNELYMMMRDCWHAVPSQR 740 Query: 1687 P-------DMDEVVQL---MEALDTS----KGGGMIPDGQSSGC 1776 P D+D +V + E LD S + PD +SS C Sbjct: 741 PTFKQLVEDLDRIVAMTSNQEYLDLSMPVDQYSPGFPDTRSSTC 784
>P54756:EPHA5_HUMAN Ephrin type-A receptor 5 precursor - Homo sapiens (Human)| Length = 1037 Score = 111 bits (277), Expect = 1e-23 Identities = 82/295 (27%), Positives = 135/295 (45%), Gaps = 9/295 (3%) Frame = +1 Query: 868 EIDLAKLEIRHVIAQGTYGTVYRGTYD--GQQ---VAVKLLDWGEDGFATEAETTALRTS 1032 EI+ + + I VI G +G V G G++ VA+K L G T R Sbjct: 669 EIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGY--------TEKQRRD 720 Query: 1033 FKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLK 1212 F E ++ + HPN+ G ++ +V EY+ G+L Sbjct: 721 FLGEASIMGQFDHPNIIHLEGVVT------------------KSKPVMIVTEYMENGSLD 762 Query: 1213 QYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGV 1392 +L KN + ++V L +S G+ YL VHRD+ N+L+++ K++DFG+ Sbjct: 763 TFLKKNDGQFTVIQLVGMLR-GISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGL 821 Query: 1393 ARVEAQNPK---DMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCC-DMPYPD 1560 +RV +P+ G + + APE + + + DV+S+GI +WEV + PY + Sbjct: 822 SRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWE 881 Query: 1561 LSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 ++ DV A V + R P CP+A +M CW + RP DE+V +++ L Sbjct: 882 MTNQDVIKA-VEEGYRLPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKL 935
>Q9SYS3:CRK40_ARATH Cysteine-rich receptor-like protein kinase 40 precursor - Arabidopsis| thaliana (Mouse-ear cress) Length = 654 Score = 111 bits (277), Expect = 1e-23 Identities = 75/220 (34%), Positives = 117/220 (53%), Gaps = 8/220 (3%) Frame = +1 Query: 898 HVIAQGTYGTVYRGTY-DGQQVAVKLLDWGEDGFATEAETTALRTSFKQEVAVWHKLSHP 1074 + + QG +GTVY+GT+ +GQ+VAVK L G E FK EV++ +L H Sbjct: 352 NTLGQGGFGTVYKGTFPNGQEVAVKRLTKGSGQGDME---------FKNEVSLLTRLQHK 402 Query: 1075 NVTKFVG-ASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYLI-KNRRRKLA 1248 N+ K +G + G ++ +V E++ +L ++ +++R L Sbjct: 403 NLVKLLGFCNEGDEEI-------------------LVYEFVPNSSLDHFIFDEDKRSLLT 443 Query: 1249 YKVVVQLALDLSRGLSYLHSR---KIVHRDVKTENMLLDTQRNLKIADFGVARV--EAQN 1413 ++V ++ ++RGL YLH KI+HRD+K N+LLD + N K+ADFG AR+ + Sbjct: 444 WEVRFRIIEGIARGLLYLHEDSQLKIIHRDLKASNILLDAEMNPKVADFGTARLFDSDET 503 Query: 1414 PKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEV 1533 + GT GYMAPE L+ + K DVYSFG+ L E+ Sbjct: 504 RAETKRIAGTRGYMAPEYLNHGQISAKSDVYSFGVMLLEM 543
>Q9LMT9:WAKLL_ARATH Putative wall-associated receptor kinase-like 13 precursor -| Arabidopsis thaliana (Mouse-ear cress) Length = 764 Score = 110 bits (276), Expect = 2e-23 Identities = 97/331 (29%), Positives = 149/331 (45%), Gaps = 22/331 (6%) Frame = +1 Query: 799 LEQQLNKKWSKSNIKSLGPKADWEIDLAKLEIRHVIAQGTYGTVYRGTY-DGQQVAVKLL 975 L+QQLN + L + E VI QG GTVY+G DG+ VAVK Sbjct: 425 LQQQLNTTQGRVEKTKLFSSRELEKATDNFNDNRVIGQGGQGTVYKGMLVDGRSVAVKKS 484 Query: 976 DWGEDGFATEAETTALRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARAN 1155 + ++ E F EV + +++H +V K +G + T ++P+ Sbjct: 485 NVVDEDKLQE---------FINEVIILSQINHRHVVKLLGCCLET---EVPI-------- 524 Query: 1156 LPARACCVVVEYLAGGTLKQYLIKNRRRKLA-YKVVVQLALDLSRGLSYLHSRK---IVH 1323 +V E++ G L Q+L + A + V +++A+D+S SYLH+ I H Sbjct: 525 -------LVYEFIPNGNLFQHLHEEFDDYTALWGVRMRIAVDISGAFSYLHTAACSPIYH 577 Query: 1324 RDVKTENMLLDTQRNLKIADFGVAR-VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCD 1500 RD+K+ N+LLD + K++DFG +R V + T +GT+GY+ PE + K D Sbjct: 578 RDIKSTNILLDEKYRAKVSDFGTSRSVSIDHTHWTTVISGTVGYVDPEYYGSSHFTEKSD 637 Query: 1501 VYSFGICLWEVYCCDMPYPDLS-------FADVSSAVVHQN---------LRPDIPRCCP 1632 VYSFG+ L E+ + P LS AD + +N +R D Sbjct: 638 VYSFGVVLVELITGEKPVITLSETQEITGLADYFRLAMRENRLFEIIDARIRNDCKLEQV 697 Query: 1633 SAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 A AN+ +C RPDM EV +E + Sbjct: 698 IAVANLALRCLKKTGKTRPDMREVSTALERI 728
>P32593:MOS_MSVMT Serine/threonine-protein kinase-transforming protein mos - Moloney| murine sarcoma virus (strain ts110) Length = 354 Score = 110 bits (276), Expect = 2e-23 Identities = 91/312 (29%), Positives = 150/312 (48%), Gaps = 20/312 (6%) Frame = +1 Query: 865 WEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFATEAETTALRTSFKQE 1044 + ID ++ + H + G +G+VY+ TY G VA+K ++ TE + A + SF E Sbjct: 67 FSIDWEQVCLMHRLGSGGFGSVYKATYHGVPVAIKQVNK-----CTE-DLRASQRSFWAE 120 Query: 1045 VAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYLI 1224 + + L H N+ + V AS T P + N +++E+ TL Q + Sbjct: 121 LNI-AGLRHDNIVRVVAASTRT-----PEDSNSLGT--------IIMEFGGNVTLHQVIY 166 Query: 1225 K--------NRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIA 1380 + R++L+ ++ +LD+ GL +LHS+ I+H D+K N+L+ Q KI+ Sbjct: 167 DATRSPEPLSCRKQLSLGKCLKYSLDVVNGLLFLHSQSILHLDLKPANILISEQDVCKIS 226 Query: 1381 DFG------VARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCC 1542 DFG V R +P + GT + APE+L G+ K D+YSFGI LW++ Sbjct: 227 DFGCSQKLQVLRGRQASPPHI---GGTYTHQAPEILKGEIATPKADIYSFGITLWQMTTR 283 Query: 1543 DMPYPDLSFADVSSAVVHQNLRPDI------PRCCPSAFANIMRKCWDGNPDKRPDMDEV 1704 ++PY V AVV NLRP + A NI++ CW+ +RP + + Sbjct: 284 EVPYSG-EPQYVQYAVVAYNLRPSLAGAVFTASLTGKALQNIIQSCWEARGLQRPSAELL 342 Query: 1705 VQLMEALDTSKG 1740 + ++A + G Sbjct: 343 QRDLKAFRGTLG 354
>Q13233:M3K1_HUMAN Mitogen-activated protein kinase kinase kinase 1 - Homo sapiens| (Human) Length = 1514 Score = 110 bits (276), Expect = 2e-23 Identities = 81/282 (28%), Positives = 135/282 (47%), Gaps = 13/282 (4%) Frame = +1 Query: 904 IAQGTYGTVYRG--TYDGQQVAVKLLDWGEDGFATEAETTALRTSFKQEVAVWHKLSHPN 1077 I G + + Y+ G +AVK + + + T +E + + ++E+ + L+HPN Sbjct: 1251 IGLGAFSSCYQAQDVGTGTLMAVKQVTYVRN---TSSEQEEVVEALREEIRMMSHLNHPN 1307 Query: 1078 VTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYLIKNRRRKLAYKV 1257 + + +GA+ ++ + +E++AGG++ L K K + V Sbjct: 1308 IIRMLGATCEKSNYNL------------------FIEWMAGGSVAHLLSKYGAFKES--V 1347 Query: 1258 VVQLALDLSRGLSYLHSRKIVHRDVKTENMLLD-TQRNLKIADFGVARVEAQNPKDMTGA 1434 V+ L RGLSYLH +I+HRDVK N+L+D T + L+IADFG A A+ TGA Sbjct: 1348 VINYTEQLLRGLSYLHENQIIHRDVKGANLLIDSTGQRLRIADFGAA---ARLASKGTGA 1404 Query: 1435 -------TGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDMPYPDLSFAD---VSS 1584 GT+ +MAPEVL G+ Y R CDV+S G + E+ C P+ ++ + Sbjct: 1405 GEFQGQLLGTIAFMAPEVLRGQQYGRSCDVWSVGCAIIEMACAKPPWNAEKHSNHLALIF 1464 Query: 1585 AVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQ 1710 + P IP ++ +C + P RP E+++ Sbjct: 1465 KIASATTAPSIPSHLSPGLRDVALRCLELQPQDRPPSRELLK 1506
>P08923:LTK_MOUSE Leukocyte tyrosine kinase receptor precursor - Mus musculus (Mouse)| Length = 888 Score = 110 bits (276), Expect = 2e-23 Identities = 89/316 (28%), Positives = 132/316 (41%), Gaps = 25/316 (7%) Frame = +1 Query: 847 LGPKADW-------EIDLAKLEIRHVIAQGTYGTVYRGTYDGQQ-------VAVKLLDWG 984 L P W E+ A + + + G +G VY G G VA+K L Sbjct: 486 LSPAQPWPLPPGLTEVSPANVTLLRALGHGAFGEVYEGLVTGLPGDSSPLPVAIKTLP-- 543 Query: 985 EDGFATEAETTALRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPA 1164 E + F E + K SH N+ + VG S + I Sbjct: 544 ------ELCSHQDELDFLMEALIISKFSHQNIVRCVGLSFRSAPRLI------------- 584 Query: 1165 RACCVVVEYLAGGTLKQYLIKNRRRK-----LAYKVVVQLALDLSRGLSYLHSRKIVHRD 1329 ++E ++GG +K +L +R L + ++QLA D+++G YL +HRD Sbjct: 585 -----LLELMSGGDMKSFLRHSRPHPGQLAPLTMQDLLQLAQDIAQGCHYLEENHFIHRD 639 Query: 1330 VKTENMLLD---TQRNLKIADFGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRK 1494 + N LL R KI DFG+AR Q G L +M PE L + K Sbjct: 640 IAARNCLLSCSGASRVAKIGDFGMARDIYQASYYRKGGRTLLPVKWMPPEALLEGLFTSK 699 Query: 1495 CDVYSFGICLWEVYCCD-MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDG 1671 D +SFG+ LWE++ MPYP + +V + N R D PR CP IM +CW Sbjct: 700 TDSWSFGVLLWEIFSLGYMPYPGHTNQEVLDFIATGN-RMDPPRNCPGPVYRIMTQCWQH 758 Query: 1672 NPDKRPDMDEVVQLME 1719 P+ RPD +++ ++ Sbjct: 759 QPELRPDFGSILERIQ 774
>Q03526:ITK_MOUSE Tyrosine-protein kinase ITK/TSK - Mus musculus (Mouse)| Length = 625 Score = 110 bits (276), Expect = 2e-23 Identities = 80/291 (27%), Positives = 139/291 (47%), Gaps = 6/291 (2%) Frame = +1 Query: 865 WEIDLAKLEIRHVIAQGTYGTVYRGTY-DGQQVAVKLLDWGEDGFATEAETTALRTSFKQ 1041 W I ++L I G +G V+ G + + +VA+K + ++G +E + F + Sbjct: 361 WVIQPSELTFVQEIGSGQFGLVHLGYWLNKDKVAIKTI---QEGAMSEED-------FIE 410 Query: 1042 EVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYL 1221 E V KLSHP + + G + + C+V E++ G L YL Sbjct: 411 EAEVMMKLSHPKLVQLYGVCLEQAPI------------------CLVFEFMEHGCLSDYL 452 Query: 1222 IKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGVARV 1401 +++R A + ++ + LD+ G++YL ++HRD+ N L+ + +K++DFG+ R Sbjct: 453 -RSQRGLFAAETLLGMCLDVCEGMAYLEKACVIHRDLAARNCLVGENQVIKVSDFGMTRF 511 Query: 1402 EAQNPKDMTGATGT---LGYMAPEVLDGKPYNRKCDVYSFGICLWEVYC-CDMPYPDLSF 1569 + T +TGT + + +PEV Y+ K DV+SFG+ +WEV+ +PY + S Sbjct: 512 VLDD--QYTSSTGTKFPVKWASPEVFSFSRYSSKSDVWSFGVLMWEVFSEGKIPYENRSN 569 Query: 1570 ADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVV-QLME 1719 ++V + R PR IM CW P+ RP +++ QL E Sbjct: 570 SEVVED-ISTGFRLYKPRLASCHVYQIMNHCWKEKPEDRPPFSQLLSQLAE 619
>P08069:IGF1R_HUMAN Insulin-like growth factor 1 receptor precursor - Homo sapiens| (Human) Length = 1367 Score = 110 bits (276), Expect = 2e-23 Identities = 85/301 (28%), Positives = 133/301 (44%), Gaps = 19/301 (6%) Frame = +1 Query: 862 DWEIDLAKLEIRHVIAQGTYGTVYRGTYDG-------QQVAVKLLDWGEDGFATEAETTA 1020 +WE+ K+ + + QG++G VY G G +VA+K ++ EA + Sbjct: 991 EWEVAREKITMSRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVN--------EAASMR 1042 Query: 1021 LRTSFKQEVAVWHKLSHPNVTKFVGA-SMGTTDLKIPVNDNGARANLPARACCVVVEYLA 1197 R F E +V + + +V + +G S G L V++E + Sbjct: 1043 ERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTL-------------------VIMELMT 1083 Query: 1198 GGTLKQYLIKNRRRKLAYKVV--------VQLALDLSRGLSYLHSRKIVHRDVKTENMLL 1353 G LK YL R V+ +Q+A +++ G++YL++ K VHRD+ N ++ Sbjct: 1084 RGDLKSYLRSLRPEMENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMV 1143 Query: 1354 DTQRNLKIADFGVARVEAQNPKDMTGATGTL--GYMAPEVLDGKPYNRKCDVYSFGICLW 1527 +KI DFG+ R + G G L +M+PE L + DV+SFG+ LW Sbjct: 1144 AEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTYSDVWSFGVVLW 1203 Query: 1528 EV-YCCDMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEV 1704 E+ + PY LS V V+ L D P CP +MR CW NP RP E+ Sbjct: 1204 EIATLAEQPYQGLSNEQVLRFVMEGGLL-DKPDNCPDMLFELMRMCWQYNPKMRPSFLEI 1262 Query: 1705 V 1707 + Sbjct: 1263 I 1263
>Q86PM4:FGFR_HYDAT Fibroblast growth factor receptor precursor - Hydra attenuata (Hydra)| (Hydra vulgaris) Length = 816 Score = 110 bits (276), Expect = 2e-23 Identities = 92/329 (27%), Positives = 146/329 (44%), Gaps = 20/329 (6%) Frame = +1 Query: 799 LEQQLNKKWSKSNIKSLGPKADWEIDLAKLEIRHVIAQGTYGTVYRGT------YDG-QQ 957 L L K N+K + P WEI L +LE ++ +G +G V+R T + G Q Sbjct: 446 LNNNLINDKQKLNLK-IAPDPAWEIKLEQLETDCLLGEGAFGRVFRATARDLPNHTGVQT 504 Query: 958 VAVKLLDWGEDGFATEAETTALRTSFKQEVAVWHKLS-HPNVTKFVGASMGTTDLKIPVN 1134 VAVK+L ED + + F E+ V + H N+ + S L I Sbjct: 505 VAVKMLK--EDCCEQDLK------DFISEIEVMKSIGKHINILNLLAVSSQQGKLYI--- 553 Query: 1135 DNGARANLPARACCVVVEYLAGGTLKQYLIKNR---------RRKLAYKVVVQLALDLSR 1287 VVEY G L+ +L NR +K+ + L ++R Sbjct: 554 ---------------VVEYCRHGNLRSFLKDNRPVMQANSVITKKITLYDLTSFCLQVAR 598 Query: 1288 GLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGVAR--VEAQNPKDMTGATGTLGYMAP 1461 G+++L S+K +HRD+ N+L+ +KIADFG+AR E + T + +MA Sbjct: 599 GMNFLASKKCIHRDIAARNVLVGEGYLMKIADFGLARDIHEQDYYRKCTDGRLPVKWMAI 658 Query: 1462 EVLDGKPYNRKCDVYSFGICLWEVYCC-DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSA 1638 E L + Y + D++SFGI WE+ PYP ++ + ++ Q R + P C Sbjct: 659 EALFDRVYTTQSDIWSFGILAWEIVTFGGSPYPGIALEKLFD-LLKQGYRMERPLNCTDD 717 Query: 1639 FANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 +M CW P KRP ++++ +E + Sbjct: 718 MYTLMLNCWKEIPSKRPTFSQLIEDLERM 746
>Q8MY85:FGFR2_DUGJA Fibroblast growth factor receptor 2 precursor - Dugesia japonica| (Planarian) Length = 887 Score = 110 bits (276), Expect = 2e-23 Identities = 85/351 (24%), Positives = 149/351 (42%), Gaps = 16/351 (4%) Frame = +1 Query: 739 LGSSDYVRADKIDLTSLDIQLEQQLNKKWSKSNIKSLGPK-ADWEIDLAKLEIRHVIAQG 915 LG +K+ SL ++ ++ + +N K + P W L I I +G Sbjct: 535 LGVISNTETNKLTSNSLTVETQRPQLILQNDANTKYILPSNIGWIFSRDSLIIGSKIGEG 594 Query: 916 TYGTVYRGTYDGQQVAVKLLDWGEDGFATEAETTALRTSFKQEVAVWHKLSHPNVTKFVG 1095 +G VY + + + E+ + E L TSF + + + + + K +G Sbjct: 595 AFGIVY---------SALVKSFSENSASVEVAIKTLHTSFGDQDVI-NLIQELEMMKIIG 644 Query: 1096 ASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYLIKNRRR------------ 1239 L DNG +V+E G L+ +L R + Sbjct: 645 RHRHIISLYGACIDNGHPY--------MVIELAKHGNLRDFLRAQRSQSKVGEIQNSGGL 696 Query: 1240 --KLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGVARVEAQN 1413 +L ++ +++++ G+ YL SRKI+HRD+ N+L+D +KIADFG+ R+ Sbjct: 697 VTRLTVTDFLRFSIEIAEGMEYLSSRKIIHRDLAARNVLVDQYVEMKIADFGLTRIVENY 756 Query: 1414 PKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCC-DMPYPDLSFADVSSAV 1590 + T + +MAPE L + Y K DV+S+GI LWE++ PYP + +D Sbjct: 757 YRKTTDGRLPIKWMAPECLLDRVYTVKSDVWSYGIVLWEIFTMGQTPYPTIQ-SDGMHQA 815 Query: 1591 VHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDTSKGG 1743 + +R + P +M W+ +P +R E++ + + S GG Sbjct: 816 LRNGIRNEKPALASDEMYRLMLTIWNDDPLERHTFSEIIDKLTHIQLSNGG 866
>Q28923:YES_CANFA Proto-oncogene tyrosine-protein kinase Yes - Canis familiaris (Dog)| Length = 539 Score = 110 bits (275), Expect = 2e-23 Identities = 81/291 (27%), Positives = 134/291 (46%), Gaps = 3/291 (1%) Frame = +1 Query: 856 KADWEIDLAKLEIRHVIAQGTYGTVYRGTYDGQ-QVAVKLLDWGEDGFATEAETTALRTS 1032 K WEI L + + QG +G V+ GT++G +VA+K L G T + + Sbjct: 263 KDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTKVAIKTLKLG----------TMMPEA 312 Query: 1033 FKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLK 1212 F QE + KL H D +P+ A + +V E+++ G+L Sbjct: 313 FLQEAQIMKKLRH--------------DKLVPLY-----AVVSEEPIYIVTEFMSKGSLL 353 Query: 1213 QYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGV 1392 +L + + L +V +A ++ G++Y+ +HRD++ N+L+ KIADFG+ Sbjct: 354 DFLKEGDGKYLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGENLVCKIADFGL 413 Query: 1393 AR-VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCD-MPYPDLS 1566 AR +E GA + + APE + K DV+SFGI E+ +PYP + Sbjct: 414 ARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILQTELTTKGRVPYPGMV 473 Query: 1567 FADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 1719 +V V + R P+ CP + +M CW +PD+RP + + +E Sbjct: 474 NREVLEQ-VERGYRMPCPQGCPESLHELMNLCWKKDPDERPTFEYIQSFLE 523
>P42683:LCK_CHICK Proto-oncogene tyrosine-protein kinase LCK - Gallus gallus (Chicken)| Length = 508 Score = 110 bits (275), Expect = 2e-23 Identities = 75/297 (25%), Positives = 139/297 (46%), Gaps = 3/297 (1%) Frame = +1 Query: 862 DWEIDLAKLEIRHVIAQGTYGTVYRGTYDGQ-QVAVKLLDWGEDGFATEAETTALRTSFK 1038 +WE+ L++ + G +G V+ G Y+G +VA+K L G + ++F Sbjct: 236 EWEVPRESLKLVEKLGAGQFGEVWMGFYNGHTKVAIKNLKQG----------SMSPSAFL 285 Query: 1039 QEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQY 1218 E + L HP + + K P+ ++ EY+ G+L + Sbjct: 286 AEANLMKNLQHPRLVRLYAVVT-----KEPIY--------------IITEYMEKGSLVDF 326 Query: 1219 LIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGVAR 1398 L + KL+ ++ +A ++ G++++ ++ +HRD++ N+L+ KIADFG+AR Sbjct: 327 LKTSEGIKLSINKLLDMAAQIAEGMAFIEAKNYIHRDLRAANILVSEALCCKIADFGLAR 386 Query: 1399 -VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCD-MPYPDLSFA 1572 +E GA + + APE ++ + K DV+SFGI L E+ +PYP ++ Sbjct: 387 LIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTYGRIPYPGMTNP 446 Query: 1573 DVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDTSKGG 1743 +V + + R P CP +M +CW P++RP + + ++E T+ G Sbjct: 447 EVIQN-LERGYRMPQPDNCPQELYELMMQCWKEQPEERPTFEYMKSVLEDFFTATEG 502
>Q95M30:HCK_MACFA Tyrosine-protein kinase HCK - Macaca fascicularis (Crab eating| macaque) (Cynomolgus monkey) Length = 504 Score = 110 bits (275), Expect = 2e-23 Identities = 78/296 (26%), Positives = 133/296 (44%), Gaps = 3/296 (1%) Frame = +1 Query: 856 KADWEIDLAKLEIRHVIAQGTYGTVYRGTYDGQ-QVAVKLLDWGEDGFATEAETTALRTS 1032 K WEI L++ + G +G V+ TY+ +VAVK + G + EA Sbjct: 230 KDAWEIPRESLKLEKKLGAGQFGEVWMATYNKHTKVAVKTMKPGS--MSVEA-------- 279 Query: 1033 FKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLK 1212 F E + L H + K A + ++ E++A G+L Sbjct: 280 FLAEANLMKTLQHDKLVKL-------------------HAVVTKEPIYIITEFMAKGSLL 320 Query: 1213 QYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGV 1392 +L + K ++ + ++ G++++ R +HRD++ N+L+ KIADFG+ Sbjct: 321 DFLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVSASLVCKIADFGL 380 Query: 1393 ARVEAQNP-KDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCD-MPYPDLS 1566 AR+ N GA + + APE ++ K DV+SFGI L E+ +PYP +S Sbjct: 381 ARIIEDNEYTAREGAKFPIKWTAPEAINFGSSTIKSDVWSFGILLMEIVTYGRIPYPGMS 440 Query: 1567 FADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDTS 1734 +V A + + R P CP NIM +CW P++RP + + +++ T+ Sbjct: 441 NPEVIRA-LERGYRMPRPENCPEELYNIMMRCWKNRPEERPTFEYIQSVLDDFYTA 495
>Q05876:FYN_CHICK Proto-oncogene tyrosine-protein kinase Fyn - Gallus gallus (Chicken)| Length = 534 Score = 110 bits (275), Expect = 2e-23 Identities = 81/291 (27%), Positives = 134/291 (46%), Gaps = 3/291 (1%) Frame = +1 Query: 856 KADWEIDLAKLEIRHVIAQGTYGTVYRGTYDGQ-QVAVKLLDWGEDGFATEAETTALRTS 1032 K WE+ L + + QG + V+RGT++G +VA+K L G T S Sbjct: 258 KDAWEVARDSLFLEQKLGQGCFAEVWRGTWNGNTKVAIKTLKPG----------TMSPES 307 Query: 1033 FKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLK 1212 F +E + KL H + + A + R +V EY++ G+L Sbjct: 308 FLEEAQIMKKLKHDKLVQLY-------------------AVVSRRPIYIVTEYMSKGSLL 348 Query: 1213 QYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGV 1392 +L R L +V +A ++ G++Y+ +HRD+++ N+L+ KIADFG+ Sbjct: 349 IFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGL 408 Query: 1393 AR-VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCD-MPYPDLS 1566 AR +E GA + + APE + K DV+SFGI L E+ +PYP ++ Sbjct: 409 ARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMN 468 Query: 1567 FADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 1719 +V V + R P+ CP + +M CW +P++RP + + +E Sbjct: 469 NREVLEQ-VERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQGFLE 518
>P16092:FGFR1_MOUSE Basic fibroblast growth factor receptor 1 precursor - Mus musculus| (Mouse) Length = 822 Score = 110 bits (275), Expect = 2e-23 Identities = 97/344 (28%), Positives = 148/344 (43%), Gaps = 40/344 (11%) Frame = +1 Query: 865 WEIDLAKLEIRHVIAQGTYGTVYRGTYDG---------QQVAVKLLDWGEDGFATEAETT 1017 WE+ +L + + +G +G V G +VAVK+L ATE + + Sbjct: 471 WELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLK----SDATEKDLS 526 Query: 1018 ALRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLA 1197 L + + + H N+ +GA L V+VEY + Sbjct: 527 DLISEMEMMKMIG---KHKNIINLLGACTQDGPLY------------------VIVEYAS 565 Query: 1198 GGTLKQYLIKNRRRKLAY--------------KVVVQLALDLSRGLSYLHSRKIVHRDVK 1335 G L++YL R L Y K +V A ++RG+ YL S+K +HRD+ Sbjct: 566 KGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLA 625 Query: 1336 TENMLLDTQRNLKIADFGVAR--VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYS 1509 N+L+ +KIADFG+AR K T + +MAPE L + Y + DV+S Sbjct: 626 ARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWS 685 Query: 1510 FGICLWEVYCC-DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKR 1686 FG+ LWE++ PYP + ++ ++ + R D P C + +MR CW P +R Sbjct: 686 FGVLLWEIFTLGGSPYPGVPVEELFK-LLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQR 744 Query: 1687 P-------DMDEVVQL---MEALDTS----KGGGMIPDGQSSGC 1776 P D+D +V L E LD S + PD +SS C Sbjct: 745 PTFKQLVEDLDRIVALTSNQEYLDLSIPLDQYSPSFPDTRSSTC 788
>P11362:FGFR1_HUMAN Basic fibroblast growth factor receptor 1 precursor - Homo sapiens| (Human) Length = 822 Score = 110 bits (275), Expect = 2e-23 Identities = 97/344 (28%), Positives = 148/344 (43%), Gaps = 40/344 (11%) Frame = +1 Query: 865 WEIDLAKLEIRHVIAQGTYGTVYRGTYDG---------QQVAVKLLDWGEDGFATEAETT 1017 WE+ +L + + +G +G V G +VAVK+L ATE + + Sbjct: 471 WELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLK----SDATEKDLS 526 Query: 1018 ALRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLA 1197 L + + + H N+ +GA L V+VEY + Sbjct: 527 DLISEMEMMKMIG---KHKNIINLLGACTQDGPLY------------------VIVEYAS 565 Query: 1198 GGTLKQYLIKNRRRKLAY--------------KVVVQLALDLSRGLSYLHSRKIVHRDVK 1335 G L++YL R L Y K +V A ++RG+ YL S+K +HRD+ Sbjct: 566 KGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLA 625 Query: 1336 TENMLLDTQRNLKIADFGVAR--VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYS 1509 N+L+ +KIADFG+AR K T + +MAPE L + Y + DV+S Sbjct: 626 ARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWS 685 Query: 1510 FGICLWEVYCC-DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKR 1686 FG+ LWE++ PYP + ++ ++ + R D P C + +MR CW P +R Sbjct: 686 FGVLLWEIFTLGGSPYPGVPVEELFK-LLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQR 744 Query: 1687 P-------DMDEVVQL---MEALDTS----KGGGMIPDGQSSGC 1776 P D+D +V L E LD S + PD +SS C Sbjct: 745 PTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTC 788
>Q07497:EPHB5_CHICK Ephrin type-B receptor 5 precursor - Gallus gallus (Chicken)| Length = 1002 Score = 110 bits (275), Expect = 2e-23 Identities = 82/298 (27%), Positives = 144/298 (48%), Gaps = 12/298 (4%) Frame = +1 Query: 868 EIDLAKLEIRHVIAQGTYGTVYRGT--YDGQQ---VAVKLLDWGEDGFATEAETTALRTS 1032 EID++ ++I VI G +G V G + G++ VA+K L + G+ E R Sbjct: 631 EIDVSFIKIEEVIGSGEFGEVCFGRLKHPGKREYTVAIKTL---KSGYTDEQ-----RRE 682 Query: 1033 FKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLK 1212 F E ++ + HPNV G +R +V E++ G+L Sbjct: 683 FLSEASIMGQFEHPNVIHLEGVVT------------------KSRPVMIVTEFMENGSLD 724 Query: 1213 QYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGV 1392 +L + + + + +V + ++ G+ YL VHRD+ N+L+++ K++DFG+ Sbjct: 725 SFL-RQKEGQFSVLQLVGMLRGIAAGMRYLSDMNYVHRDLAARNILVNSNLVCKVSDFGL 783 Query: 1393 ARV---EAQNPKDMTGATG---TLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCC-DMP 1551 +R +A NP TGA G + + APE + + + DV+S+GI +WEV + P Sbjct: 784 SRFLEDDASNP-TYTGALGCKIPIRWTAPEAVQYRKFTSSSDVWSYGIVMWEVMSYGERP 842 Query: 1552 YPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 Y D+S DV +A + Q+ R P CP+ +M CW + +RP +++V ++ + Sbjct: 843 YWDMSNQDVINA-IDQDYRLPPPPDCPTVLHLLMLDCWQKDRVQRPKFEQIVSALDKM 899
>P54761:EPHB4_MOUSE Ephrin type-B receptor 4 precursor - Mus musculus (Mouse)| Length = 987 Score = 110 bits (275), Expect = 2e-23 Identities = 80/297 (26%), Positives = 137/297 (46%), Gaps = 11/297 (3%) Frame = +1 Query: 868 EIDLAKLEIRHVIAQGTYGTVYRGTYDGQQ-----VAVKLLDWGEDGFATEAETTALRTS 1032 EID++ ++I VI G +G V RG VA+K L G T R Sbjct: 609 EIDVSYVKIEEVIGAGEFGEVCRGRLKAPGKKESCVAIKTLKGGY--------TERQRRE 660 Query: 1033 FKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLK 1212 F E ++ + HPN+ + G + +PV ++ E++ G L Sbjct: 661 FLSEASIMGQFEHPNIIRLEGVVTNS----VPV--------------MILTEFMENGALD 702 Query: 1213 QYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGV 1392 +L N + ++V L ++ G+ YL VHRD+ N+L+++ K++DFG+ Sbjct: 703 SFLRLNDGQFTVIQLVGMLR-GIASGMRYLAEMSYVHRDLAARNILVNSNLVCKVSDFGL 761 Query: 1393 ARVEAQNPKDMT-----GATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCC-DMPY 1554 +R +N D T G ++ + APE + + + D +S+GI +WEV + PY Sbjct: 762 SRFLEENSSDPTYTSSLGGKISIRWTAPEAIAFRKFTSASDAWSYGIVMWEVMSFGERPY 821 Query: 1555 PDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 D+S DV +A + Q+ R P CP++ +M CW + + RP +VV ++ + Sbjct: 822 WDMSNQDVINA-IEQDYRLPPPPDCPTSLHQLMLDCWQKDRNARPRFPQVVSALDKM 877
>P54763:EPHB2_MOUSE Ephrin type-B receptor 2 precursor - Mus musculus (Mouse)| Length = 994 Score = 110 bits (275), Expect = 2e-23 Identities = 81/297 (27%), Positives = 138/297 (46%), Gaps = 11/297 (3%) Frame = +1 Query: 868 EIDLAKLEIRHVIAQGTYGTVYRG--TYDGQQ---VAVKLLDWGEDGFATEAETTALRTS 1032 EID++ ++I VI G +G V G G++ VA+K L G T R Sbjct: 623 EIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGY--------TEKQRRD 674 Query: 1033 FKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLK 1212 F E ++ + HPNV G +T + I + E++ G+L Sbjct: 675 FLSEASIMGQFDHPNVIHLEGVVTKSTPVMI------------------ITEFMENGSLD 716 Query: 1213 QYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGV 1392 +L +N + ++V L ++ G+ YL VHRD+ N+L+++ K++DFG+ Sbjct: 717 SFLRQNDGQFTVIQLVGMLR-GIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGL 775 Query: 1393 ARVEAQNPKDMT-----GATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCC-DMPY 1554 +R + D T G + + APE + + + DV+S+GI +WEV + PY Sbjct: 776 SRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPY 835 Query: 1555 PDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 D++ DV +A + Q+ R P CPSA +M CW + + RP ++V ++ + Sbjct: 836 WDMTNQDVINA-IEQDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKM 891
>P29323:EPHB2_HUMAN Ephrin type-B receptor 2 precursor - Homo sapiens (Human)| Length = 1055 Score = 110 bits (275), Expect = 2e-23 Identities = 81/297 (27%), Positives = 138/297 (46%), Gaps = 11/297 (3%) Frame = +1 Query: 868 EIDLAKLEIRHVIAQGTYGTVYRG--TYDGQQ---VAVKLLDWGEDGFATEAETTALRTS 1032 EID++ ++I VI G +G V G G++ VA+K L G T R Sbjct: 615 EIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGY--------TEKQRRD 666 Query: 1033 FKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLK 1212 F E ++ + HPNV G +T + I + E++ G+L Sbjct: 667 FLSEASIMGQFDHPNVIHLEGVVTKSTPVMI------------------ITEFMENGSLD 708 Query: 1213 QYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGV 1392 +L +N + ++V L ++ G+ YL VHRD+ N+L+++ K++DFG+ Sbjct: 709 SFLRQNDGQFTVIQLVGMLR-GIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGL 767 Query: 1393 ARVEAQNPKDMT-----GATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCC-DMPY 1554 +R + D T G + + APE + + + DV+S+GI +WEV + PY Sbjct: 768 SRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPY 827 Query: 1555 PDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 D++ DV +A + Q+ R P CPSA +M CW + + RP ++V ++ + Sbjct: 828 WDMTNQDVINA-IEQDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKM 883
>Q60629:EPHA5_MOUSE Ephrin type-A receptor 5 precursor - Mus musculus (Mouse)| Length = 877 Score = 110 bits (275), Expect = 2e-23 Identities = 81/295 (27%), Positives = 136/295 (46%), Gaps = 9/295 (3%) Frame = +1 Query: 868 EIDLAKLEIRHVIAQGTYGTVYRGTYD--GQQ---VAVKLLDWGEDGFATEAETTALRTS 1032 EI+ + + I VI G +G V G G++ VA+K L G T R Sbjct: 508 EIEASCITIERVIGAGEFGEVCSGCLKLPGKRELPVAIKTLKVGY--------TEKQRRD 559 Query: 1033 FKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLK 1212 F E ++ + HPN+ G ++ +V EY+ G+L Sbjct: 560 FLGEASIMGQFDHPNIIHLEGVVT------------------KSKPVMIVTEYMENGSLD 601 Query: 1213 QYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGV 1392 +L KN + ++V L ++ G+ YL VHRD+ N+L+++ K++DFG+ Sbjct: 602 TFLKKNDGQFTVIQLVGMLR-GIAAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGL 660 Query: 1393 ARVEAQNPK---DMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCC-DMPYPD 1560 +RV +P+ G + + APE + + + DV+S+GI +WEV + PY + Sbjct: 661 SRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWE 720 Query: 1561 LSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 ++ DV A V + R P CP+A +M CW + + RP DE+V +++ L Sbjct: 721 MTNQDVIKA-VEEGYRLPSPMDCPAALYQLMLDCWQKDRNSRPKFDEIVNMLDKL 774
>Q04736:YES_MOUSE Proto-oncogene tyrosine-protein kinase Yes - Mus musculus (Mouse)| Length = 541 Score = 110 bits (274), Expect = 3e-23 Identities = 81/291 (27%), Positives = 134/291 (46%), Gaps = 3/291 (1%) Frame = +1 Query: 856 KADWEIDLAKLEIRHVIAQGTYGTVYRGTYDGQ-QVAVKLLDWGEDGFATEAETTALRTS 1032 K WEI L + + QG +G V+ GT++G +VA+K L G T + + Sbjct: 265 KDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTKVAIKTLKPG----------TMMPEA 314 Query: 1033 FKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLK 1212 F QE + KL H D +P+ A + +V E+++ G+L Sbjct: 315 FLQEAQIMKKLRH--------------DKLVPLY-----AVVSEEPIYIVTEFMSKGSLL 355 Query: 1213 QYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGV 1392 +L + + L +V +A ++ G++Y+ +HRD++ N+L+ KIADFG+ Sbjct: 356 DFLKEGDGKYLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGENLICKIADFGL 415 Query: 1393 AR-VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCD-MPYPDLS 1566 AR +E GA + + APE + K DV+SFGI E+ +PYP + Sbjct: 416 ARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILQTELVTKGRVPYPGMV 475 Query: 1567 FADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 1719 +V V + R P+ CP + +M CW +PD+RP + + +E Sbjct: 476 NREVLEQ-VERGYRMPCPQGCPESLHELMNLCWKKDPDERPTFEYIQSFLE 525
>P07947:YES_HUMAN Proto-oncogene tyrosine-protein kinase Yes - Homo sapiens (Human)| Length = 543 Score = 110 bits (274), Expect = 3e-23 Identities = 81/291 (27%), Positives = 134/291 (46%), Gaps = 3/291 (1%) Frame = +1 Query: 856 KADWEIDLAKLEIRHVIAQGTYGTVYRGTYDGQ-QVAVKLLDWGEDGFATEAETTALRTS 1032 K WEI L + + QG +G V+ GT++G +VA+K L G T + + Sbjct: 267 KDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTKVAIKTLKPG----------TMMPEA 316 Query: 1033 FKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLK 1212 F QE + KL H D +P+ A + +V E+++ G+L Sbjct: 317 FLQEAQIMKKLRH--------------DKLVPLY-----AVVSEEPIYIVTEFMSKGSLL 357 Query: 1213 QYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGV 1392 +L + + L +V +A ++ G++Y+ +HRD++ N+L+ KIADFG+ Sbjct: 358 DFLKEGDGKYLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGENLVCKIADFGL 417 Query: 1393 AR-VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCD-MPYPDLS 1566 AR +E GA + + APE + K DV+SFGI E+ +PYP + Sbjct: 418 ARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILQTELVTKGRVPYPGMV 477 Query: 1567 FADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 1719 +V V + R P+ CP + +M CW +PD+RP + + +E Sbjct: 478 NREVLEQ-VERGYRMPCPQGCPESLHELMNLCWKKDPDERPTFEYIQSFLE 527
>P63185:SRC_RSVSE Tyrosine-protein kinase transforming protein Src - Rous sarcoma virus| (strain Schmidt-Ruppin E) (RSV-SR-E) Length = 526 Score = 110 bits (274), Expect = 3e-23 Identities = 86/303 (28%), Positives = 139/303 (45%), Gaps = 4/303 (1%) Frame = +1 Query: 826 SKSNIKSLGPKADWEIDLAKLEIRHVIAQGTYGTVYRGTYDGQ-QVAVKLLDWGEDGFAT 1002 SK + L A WEI L + + QG +G V+ GT++G +VA+K L G Sbjct: 248 SKPQTQGLAKDA-WEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPG------ 300 Query: 1003 EAETTALRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVV 1182 T +F QE V KL H + + A + +V Sbjct: 301 ----TMSPEAFLQEAQVMKKLRHKKLVQLY-------------------AVVSEEPIYIV 337 Query: 1183 VEYLAGGTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQ 1362 +EY++ G+L +L + L +V +A ++ G++Y+ VHRD++ N+L+ Sbjct: 338 IEYMSKGSLLDFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGEN 397 Query: 1363 RNLKIADFGVAR-VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYC 1539 K+ADFG+AR +E GA + + APE + K DV+SFGI L E+ Sbjct: 398 LVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTT 457 Query: 1540 CD-MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEV-VQL 1713 +PYP + +V V + R P CP + ++M +CW +P++RP + + QL Sbjct: 458 KGRVPYPGMGNGEVLDR-VERGYRMPCPPECPESLHDLMSQCWRRDPEERPTFEYLQAQL 516 Query: 1714 MEA 1722 + A Sbjct: 517 LPA 519
>P53349:M3K1_MOUSE Mitogen-activated protein kinase kinase kinase 1 - Mus musculus| (Mouse) Length = 1493 Score = 110 bits (274), Expect = 3e-23 Identities = 81/282 (28%), Positives = 135/282 (47%), Gaps = 13/282 (4%) Frame = +1 Query: 904 IAQGTYGTVYRG--TYDGQQVAVKLLDWGEDGFATEAETTALRTSFKQEVAVWHKLSHPN 1077 I G + + Y+ G +AVK + + + T +E + + ++E+ + L+HPN Sbjct: 1230 IGLGAFSSCYQAQDVGTGTLMAVKQVTYVRN---TSSEQEEVVEALREEIRMMGHLNHPN 1286 Query: 1078 VTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYLIKNRRRKLAYKV 1257 + + +GA+ ++ + +E++AGG++ L K K + V Sbjct: 1287 IIRMLGATCEKSNYNL------------------FIEWMAGGSVAHLLSKYGAFKES--V 1326 Query: 1258 VVQLALDLSRGLSYLHSRKIVHRDVKTENMLLD-TQRNLKIADFGVARVEAQNPKDMTGA 1434 V+ L RGLSYLH +I+HRDVK N+L+D T + L+IADFG A A+ TGA Sbjct: 1327 VINYTEQLLRGLSYLHENQIIHRDVKGANLLIDSTGQRLRIADFGAA---ARLASKGTGA 1383 Query: 1435 -------TGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDMPYPDLSFAD---VSS 1584 GT+ +MAPEVL G+ Y R CDV+S G + E+ C P+ ++ + Sbjct: 1384 GEFQGQLLGTIAFMAPEVLRGQQYGRSCDVWSVGCAIIEMACAKPPWNAEKHSNHLALIF 1443 Query: 1585 AVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQ 1710 + P IP ++ +C + P RP E+++ Sbjct: 1444 KIASATTAPSIPSHLSPGLRDVAVRCLELQPQDRPPSRELLK 1485
>Q62662:FRK_RAT Tyrosine-protein kinase FRK - Rattus norvegicus (Rat)| Length = 506 Score = 110 bits (274), Expect = 3e-23 Identities = 78/284 (27%), Positives = 133/284 (46%), Gaps = 6/284 (2%) Frame = +1 Query: 865 WEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQ-VAVKLLDWGEDGFATEAETTALRTSFKQ 1041 WEID +++ + G +G V+ G ++ VAVK L G F + Sbjct: 228 WEIDRNSIQLLKRLGSGQFGEVWEGLWNNTTPVAVKTLKPGSMD----------PNDFLR 277 Query: 1042 EVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYL 1221 E + L HP + + L+ P+ ++ E + G+L++YL Sbjct: 278 EAQIMKSLRHPKLIQLYAVCT----LEDPIY--------------IITELMRHGSLQEYL 319 Query: 1222 IKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGVARV 1401 + K+ V +A ++ G++YL S+ +HRD+ N+L+ K+ADFG+ARV Sbjct: 320 QNDGGSKIRLTQQVDMAAQVASGMAYLESQNYIHRDLAARNVLVGEHNIYKVADFGLARV 379 Query: 1402 EAQNPKDMTGATGTL----GYMAPEVLDGKPYNRKCDVYSFGICLWEVYCC-DMPYPDLS 1566 + +D+ + + + APE + ++ K DV+SFGI L+E+ MPY ++ Sbjct: 380 FKVDNEDIYESKHEIKLPVKWTAPEAIRTNKFSIKSDVWSFGILLYEIITYGKMPYSGMT 439 Query: 1567 FADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMD 1698 A V ++ QN R P CP F +IM +CW+ P +RP + Sbjct: 440 GAQVIH-MLGQNYRLPQPSNCPEQFYSIMMECWNVEPKQRPTFE 482
>P29322:EPHA8_HUMAN Ephrin type-A receptor 8 precursor - Homo sapiens (Human)| Length = 1005 Score = 110 bits (274), Expect = 3e-23 Identities = 80/295 (27%), Positives = 134/295 (45%), Gaps = 9/295 (3%) Frame = +1 Query: 868 EIDLAKLEIRHVIAQGTYGTVYRGTY--DGQQ---VAVKLLDWGEDGFATEAETTALRTS 1032 EI+ +++ I +I G G V G GQ+ VA+K L G T R Sbjct: 629 EIEASRIHIEKIIGSGDSGEVCYGRLRVPGQRDVPVAIKALKAGY--------TERQRRD 680 Query: 1033 FKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLK 1212 F E ++ + HPN+ + G R +V EY+ G+L Sbjct: 681 FLSEASIMGQFDHPNIIRLEGVVTR------------------GRLAMIVTEYMENGSLD 722 Query: 1213 QYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGV 1392 +L + + +V + + G+ YL VHRD+ N+L+D+ K++DFG+ Sbjct: 723 TFL-RTHDGQFTIMQLVGMLRGVGAGMRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGL 781 Query: 1393 ARVEAQNPK---DMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCC-DMPYPD 1560 +RV +P TG + + APE + + ++ DV+SFG+ +WEV + PY + Sbjct: 782 SRVLEDDPDAAYTTTGGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWN 841 Query: 1561 LSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 ++ DV S+ V + R P CP A +M CW + +RP ++V +++AL Sbjct: 842 MTNRDVISS-VEEGYRLPAPMGCPHALHQLMLDCWHKDRAQRPRFSQIVSVLDAL 895
>P29318:EPHA3_CHICK Ephrin type-A receptor 3 precursor - Gallus gallus (Chicken)| Length = 983 Score = 110 bits (274), Expect = 3e-23 Identities = 77/295 (26%), Positives = 135/295 (45%), Gaps = 9/295 (3%) Frame = +1 Query: 868 EIDLAKLEIRHVIAQGTYGTVYRG-----TYDGQQVAVKLLDWGEDGFATEAETTALRTS 1032 E+D + + I V+ G +G V G + VA+K L G T R Sbjct: 615 ELDASNISIDKVVGAGEFGEVCSGRLKLPSKKEISVAIKTLKAGY--------TEKQRRD 666 Query: 1033 FKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLK 1212 F E ++ + HPN+ + G ++ +V EY+ G+L Sbjct: 667 FLGEASIMGQFDHPNIIRLEGVVT------------------KSKPVMIVTEYMENGSLD 708 Query: 1213 QYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGV 1392 +L K+ + ++V L ++ G+ YL VHRD+ N+L+++ K++DFG+ Sbjct: 709 SFLRKHDAQFTVIQLVGMLR-GIASGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGL 767 Query: 1393 ARVEAQNPK---DMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCC-DMPYPD 1560 +RV +P+ G + + +PE + + + D +S+GI LWEV + PY + Sbjct: 768 SRVLEDDPEAAYTTRGGKIPIRWTSPEAIAYRKFTSASDAWSYGIVLWEVMSYGERPYWE 827 Query: 1561 LSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 +SF DV A V + R P CP+A +M CW + + RP +++V +++ L Sbjct: 828 MSFQDVIKA-VDEGYRLPPPMDCPAALYQLMLDCWQKDRNNRPKFEQIVSILDKL 881
>Q91694:EPA4B_XENLA Ephrin type-A receptor 4-B precursor - Xenopus laevis (African clawed| frog) Length = 985 Score = 110 bits (274), Expect = 3e-23 Identities = 85/295 (28%), Positives = 135/295 (45%), Gaps = 9/295 (3%) Frame = +1 Query: 868 EIDLAKLEIRHVIAQGTYGTVYRGTYD--GQQ---VAVKLLDWGEDGFATEAETTALRTS 1032 EID + ++I VI G +G V G G++ VA+K L G T R Sbjct: 614 EIDASCIKIEKVIGVGEFGEVCSGRLKVPGKREIYVAIKTLKAGY--------TDKQRRD 665 Query: 1033 FKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLK 1212 F E ++ + HPN+ G T K PV ++ EY+ G+L Sbjct: 666 FLSEASIMGQFDHPNIIHLEGV---VTKCK-PV--------------MIITEYMENGSLD 707 Query: 1213 QYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGV 1392 +L KN R ++V L + G+ YL VHRD+ N+L+++ K++DFG+ Sbjct: 708 AFLRKNDGRFTVIQLVGMLR-GIGSGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGM 766 Query: 1393 ARVEAQNPK---DMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCC-DMPYPD 1560 +RV +P+ G + + APE + + + DV+S+GI +WEV + PY D Sbjct: 767 SRVLEDDPEAAYTTRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWD 826 Query: 1561 LSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 +S DV A + + R P CP A +M CW + RP ++V +++ L Sbjct: 827 MSNQDVIKA-IEEGYRLPPPMDCPIALHQLMLDCWQKDRSDRPKFGQIVSMLDKL 880
>Q9S9M3:WAKLC_ARATH Wall-associated receptor kinase-like 3 precursor - Arabidopsis| thaliana (Mouse-ear cress) Length = 730 Score = 109 bits (273), Expect = 4e-23 Identities = 97/345 (28%), Positives = 155/345 (44%), Gaps = 19/345 (5%) Frame = +1 Query: 757 VRADKIDLTSLDIQLEQQLNKKWSKSNIKSLGPKADWEIDLAKLEIRHVIAQGTYGTVY- 933 +R+ K + + L+QQL K + + + E I V+ QG GTVY Sbjct: 385 IRSMKFFKRNGGLLLKQQLTTKDGSVEMSKIFSSRELEKATDNFSIDRVLGQGGQGTVYK 444 Query: 934 RGTYDGQQVAVKLLDWGEDGFATEAETTALRTSFKQEVAVWHKLSHPNVTKFVGASMGTT 1113 R DG VAVK ++ E F E+ + +++H N+ K +G + T Sbjct: 445 RMLVDGSIVAVKRSKVVDEDKMEE---------FINEIVLLSQINHRNIVKLLGCCLET- 494 Query: 1114 DLKIPVNDNGARANLPARACCVVVEYLAGGTL-KQYLIKNRRRKLAYKVVVQLALDLSRG 1290 ++P+ +V EY+ G L K+ + + ++V +++A++++ Sbjct: 495 --EVPI---------------LVYEYIPNGDLFKRLHDEYDDYMMTWEVRLRIAVEIAGA 537 Query: 1291 LSYLHSRK---IVHRDVKTENMLLDTQRNLKIADFGVARVEAQNPKDMTG-ATGTLGYMA 1458 LSY+HS I HRD+KT N+LLD + KI+DFG +R A + +T GT GYM Sbjct: 538 LSYMHSAASFPIFHRDIKTTNILLDEKYRAKISDFGTSRSVATDQTHLTTLVAGTFGYMD 597 Query: 1459 PEVLDGKPYNRKCDVYSFGICLWEVYCCDMPY------PDLSFADVSSAVVHQNLRPDI- 1617 PE Y K DVYSFG+ L E+ + P + A + +N DI Sbjct: 598 PEYFLSSQYTHKSDVYSFGVVLVELITGEKPMSRVRSEEGIGLATYFLEAMKENRAVDII 657 Query: 1618 ------PRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDTS 1734 A A + R+C + +KRP+M EV +E + +S Sbjct: 658 DIRIKDESKQVMAVAKLARRCLNRKGNKRPNMREVSIKLERIRSS 702
>Q04912:RON_HUMAN Macrophage-stimulating protein receptor precursor - Homo sapiens| (Human) Length = 1400 Score = 109 bits (273), Expect = 4e-23 Identities = 87/289 (30%), Positives = 136/289 (47%), Gaps = 14/289 (4%) Frame = +1 Query: 901 VIAQGTYGTVYRGTYDGQ-----QVAVKLLDWGEDGFATEAETTALRTSFKQEVAVWHKL 1065 VI +G +G VY G Y Q Q A+K L + EA F +E + L Sbjct: 1087 VIGKGHFGVVYHGEYIDQAQNRIQCAIKSLSRITEMQQVEA--------FLREGLLMRGL 1138 Query: 1066 SHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYLIKNRRRKL 1245 +HPNV +G + +P P V++ Y+ G L Q+ I++ +R Sbjct: 1139 NHPNVLALIG-------IMLP----------PEGLPHVLLPYMCHGDLLQF-IRSPQRNP 1180 Query: 1246 AYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGVAR----VEAQN 1413 K ++ L ++RG+ YL +K VHRD+ N +LD +K+ADFG+AR E + Sbjct: 1181 TVKDLISFGLQVARGMEYLAEQKFVHRDLAARNCMLDESFTVKVADFGLARDILDREYYS 1240 Query: 1414 PKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDM-PYPDLSFADVSSAV 1590 + A + +MA E L + K DV+SFG+ LWE+ PY + D++ + Sbjct: 1241 VQQHRHARLPVKWMALESLQTYRFTTKSDVWSFGVLLWELLTRGAPPYRHIDPFDLTHFL 1300 Query: 1591 VHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPD----MDEVVQLMEAL 1725 Q R P CP + +M++CW+ +P RP + EV Q++ AL Sbjct: 1301 A-QGRRLPQPEYCPDSLYQVMQQCWEADPAVRPTFRVLVGEVEQIVSAL 1348
>P06239:LCK_HUMAN Proto-oncogene tyrosine-protein kinase LCK - Homo sapiens (Human)| Length = 509 Score = 109 bits (273), Expect = 4e-23 Identities = 81/306 (26%), Positives = 138/306 (45%), Gaps = 8/306 (2%) Frame = +1 Query: 862 DWEIDLAKLEIRHVIAQGTYGTVYRGTYDGQ-QVAVKLLDWGE---DGFATEAETTALRT 1029 +WE+ L++ + G +G V+ G Y+G +VAVK L G D F EA Sbjct: 237 EWEVPRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEAN------ 290 Query: 1030 SFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTL 1209 + +L H + + A + ++ EY+ G+L Sbjct: 291 -------LMKQLQHQRLVRLY-------------------AVVTQEPIYIITEYMENGSL 324 Query: 1210 KQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFG 1389 +L KL ++ +A ++ G++++ R +HRD++ N+L+ + KIADFG Sbjct: 325 VDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFG 384 Query: 1390 VAR-VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCD-MPYPDL 1563 +AR +E GA + + APE ++ + K DV+SFGI L E+ +PYP + Sbjct: 385 LARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGM 444 Query: 1564 SFADVSSAVV--HQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDTSK 1737 + +V + ++ +RPD CP +MR CW P+ RP D + ++E T+ Sbjct: 445 TNPEVIQNLERGYRMVRPD---NCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDFFTAT 501 Query: 1738 GGGMIP 1755 G P Sbjct: 502 EGQYQP 507
>Q61851:FGFR3_MOUSE Fibroblast growth factor receptor 3 precursor - Mus musculus (Mouse)| Length = 801 Score = 109 bits (273), Expect = 4e-23 Identities = 98/361 (27%), Positives = 155/361 (42%), Gaps = 47/361 (13%) Frame = +1 Query: 832 SNIKSLGPKAD--WEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQ---------VAVKLLD 978 +N+ L AD WE+ +L + + +G +G V G VAVK+L Sbjct: 446 ANVSELELPADPKWELSRTRLTLGKPLGEGCFGQVVMAEAIGIDKDRTAKPVTVAVKMLK 505 Query: 979 WGEDGFATEAETTALRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANL 1158 +D AT+ + + L + + + H N+ +GA L Sbjct: 506 --DD--ATDKDLSDLVSEMEMMKMIG---KHKNIINLLGACTQGGPLY------------ 546 Query: 1159 PARACCVVVEYLAGGTLKQYLIKNR--------------RRKLAYKVVVQLALDLSRGLS 1296 V+VEY A G L+++L R +L K +V A ++RG+ Sbjct: 547 ------VLVEYAAKGNLREFLRARRPPGMDYSFDACRLPEEQLTCKDLVSCAYQVARGME 600 Query: 1297 YLHSRKIVHRDVKTENMLLDTQRNLKIADFGVARVEAQN---PKDMTGATGTLGYMAPEV 1467 YL S+K +HRD+ N+L+ +KIADFG+AR + N K T + +MAPE Sbjct: 601 YLASQKCIHRDLAARNVLVTEDNVMKIADFGLAR-DVHNLDYYKKTTNGRLPVKWMAPEA 659 Query: 1468 LDGKPYNRKCDVYSFGICLWEVYC--CDMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAF 1641 L + Y + DV+SFG+ LWE++ PYP + ++ ++ + R D P C Sbjct: 660 LFDRVYTHQSDVWSFGVLLWEIFTPGGPSPYPGIPVEELFK-LLKEGHRMDKPASCTHDL 718 Query: 1642 ANIMRKCWDGNPDKRPDMDEVVQLMEALDT-----------------SKGGGMIPDGQSS 1770 IMR+CW P +RP ++V+ ++ + T S GG P SS Sbjct: 719 YMIMRECWHAVPSQRPTFKQLVEDLDRILTVTSTDEYLDLSVPFEQYSPGGQDTPSSSSS 778 Query: 1771 G 1773 G Sbjct: 779 G 779
>Q91735:EPHB3_XENLA Ephrin type-B receptor 3 precursor - Xenopus laevis (African clawed| frog) Length = 974 Score = 109 bits (273), Expect = 4e-23 Identities = 82/297 (27%), Positives = 135/297 (45%), Gaps = 11/297 (3%) Frame = +1 Query: 868 EIDLAKLEIRHVIAQGTYGTVYRGTYDG-----QQVAVKLLDWGEDGFATEAETTALRTS 1032 EID++ ++I VI G +G V RG Q VA+K L G T R Sbjct: 603 EIDISCVKIEEVIGAGEFGEVCRGKLKQAGRREQFVAIKTLKAGY--------TEQQRRD 654 Query: 1033 FKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLK 1212 F E ++ + HPN+ + G + R ++ E++ G L Sbjct: 655 FLGEASIMGQFDHPNIIRLEGVVTRS------------------RPVMILTEFMENGALD 696 Query: 1213 QYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGV 1392 +L N + ++V L ++ G+ YL VHRD+ N+L+++ K++DFG+ Sbjct: 697 SFLRMNDGQFTVIQLVGILR-GIASGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGL 755 Query: 1393 ARVEAQNPKDMT-----GATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCC-DMPY 1554 +R + D T G + + APE + + + DV+S+GI +WEV + PY Sbjct: 756 SRFLENSRSDPTYTSALGGKIPIRWTAPEAISYRKFTSASDVWSYGIVMWEVMSYGERPY 815 Query: 1555 PDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 D+S DV +A + Q+ R P CPSA +M CW + + RP ++V ++ L Sbjct: 816 WDMSNQDVINA-IEQDYRLPPPMDCPSALHQLMLDCWLRDRNLRPKFSQIVSSLDKL 871
>P54754:EPHB3_MOUSE Ephrin type-B receptor 3 precursor - Mus musculus (Mouse)| Length = 993 Score = 109 bits (273), Expect = 4e-23 Identities = 84/298 (28%), Positives = 139/298 (46%), Gaps = 12/298 (4%) Frame = +1 Query: 868 EIDLAKLEIRHVIAQGTYGTVYRGTYD--GQQ---VAVKLLDWGEDGFATEAETTALRTS 1032 EID++ ++I VI G +G V RG G++ VA+K L G T R Sbjct: 622 EIDVSCVKIEEVIGAGEFGEVCRGRLKLPGRREVFVAIKTLKVGY--------TERQRRD 673 Query: 1033 FKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLK 1212 F E ++ + HPN+ + G +R ++ E++ L Sbjct: 674 FLSEASIMGQFDHPNIIRLEGVVT------------------KSRPVMILTEFMENCALD 715 Query: 1213 QYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGV 1392 +L N + ++V L ++ G+ YL VHRD+ N+L+++ K++DFG+ Sbjct: 716 SFLRLNDGQFTVIQLVGMLR-GIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGL 774 Query: 1393 ARVEAQNPKDMTGATGTLG------YMAPEVLDGKPYNRKCDVYSFGICLWEVYCC-DMP 1551 +R +P D T T +LG + APE + + + DV+S+GI +WEV + P Sbjct: 775 SRFLEDDPSDPT-YTSSLGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERP 833 Query: 1552 YPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 Y D+S DV +A V Q+ R P CP+A +M CW + + RP ++V ++ L Sbjct: 834 YWDMSNQDVINA-VEQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFSQIVNTLDKL 890
>P54753:EPHB3_HUMAN Ephrin type-B receptor 3 precursor - Homo sapiens (Human)| Length = 998 Score = 109 bits (273), Expect = 4e-23 Identities = 84/298 (28%), Positives = 139/298 (46%), Gaps = 12/298 (4%) Frame = +1 Query: 868 EIDLAKLEIRHVIAQGTYGTVYRGTYD--GQQ---VAVKLLDWGEDGFATEAETTALRTS 1032 EID++ ++I VI G +G V RG G++ VA+K L G T R Sbjct: 627 EIDVSCVKIEEVIGAGEFGEVCRGRLKQPGRREVFVAIKTLKVGY--------TERQRRD 678 Query: 1033 FKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLK 1212 F E ++ + HPN+ + G +R ++ E++ L Sbjct: 679 FLSEASIMGQFDHPNIIRLEGVVT------------------KSRPVMILTEFMENCALD 720 Query: 1213 QYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGV 1392 +L N + ++V L ++ G+ YL VHRD+ N+L+++ K++DFG+ Sbjct: 721 SFLRLNDGQFTVIQLVGMLR-GIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGL 779 Query: 1393 ARVEAQNPKDMTGATGTLG------YMAPEVLDGKPYNRKCDVYSFGICLWEVYCC-DMP 1551 +R +P D T T +LG + APE + + + DV+S+GI +WEV + P Sbjct: 780 SRFLEDDPSDPT-YTSSLGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERP 838 Query: 1552 YPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 Y D+S DV +A V Q+ R P CP+A +M CW + + RP ++V ++ L Sbjct: 839 YWDMSNQDVINA-VEQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFSQIVNTLDKL 895
>Q03137:EPHA4_MOUSE Ephrin type-A receptor 4 precursor - Mus musculus (Mouse)| Length = 986 Score = 109 bits (273), Expect = 4e-23 Identities = 85/295 (28%), Positives = 134/295 (45%), Gaps = 9/295 (3%) Frame = +1 Query: 868 EIDLAKLEIRHVIAQGTYGTVYRGTYD--GQQ---VAVKLLDWGEDGFATEAETTALRTS 1032 EID + ++I VI G +G V G G++ VA+K L G T R Sbjct: 615 EIDASCIKIEKVIGVGEFGEVCSGRLKVPGKREICVAIKTLKAGY--------TDKQRRD 666 Query: 1033 FKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLK 1212 F E ++ + HPN+ G T K PV ++ EY+ G+L Sbjct: 667 FLSEASIMGQFDHPNIIHLEGV---VTKCK-PV--------------MIITEYMENGSLD 708 Query: 1213 QYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGV 1392 +L KN R ++V L + G+ YL VHRD+ N+L+++ K++DFG+ Sbjct: 709 AFLRKNDGRFTVIQLVGMLR-GIGSGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGM 767 Query: 1393 ARVEAQNPK---DMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCC-DMPYPD 1560 +RV +P+ G + + APE + + + DV+S+GI +WEV + PY D Sbjct: 768 SRVLEDDPEAAYTTRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWD 827 Query: 1561 LSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 +S DV A + + R P CP A +M CW RP ++V +++ L Sbjct: 828 MSNQDVIKA-IEEGYRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNMLDKL 881
>P54764:EPHA4_HUMAN Ephrin type-A receptor 4 precursor - Homo sapiens (Human)| Length = 986 Score = 109 bits (273), Expect = 4e-23 Identities = 85/295 (28%), Positives = 134/295 (45%), Gaps = 9/295 (3%) Frame = +1 Query: 868 EIDLAKLEIRHVIAQGTYGTVYRGTYD--GQQ---VAVKLLDWGEDGFATEAETTALRTS 1032 EID + ++I VI G +G V G G++ VA+K L G T R Sbjct: 615 EIDASCIKIEKVIGVGEFGEVCSGRLKVPGKREICVAIKTLKAGY--------TDKQRRD 666 Query: 1033 FKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLK 1212 F E ++ + HPN+ G T K PV ++ EY+ G+L Sbjct: 667 FLSEASIMGQFDHPNIIHLEGV---VTKCK-PV--------------MIITEYMENGSLD 708 Query: 1213 QYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGV 1392 +L KN R ++V L + G+ YL VHRD+ N+L+++ K++DFG+ Sbjct: 709 AFLRKNDGRFTVIQLVGMLR-GIGSGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGM 767 Query: 1393 ARVEAQNPK---DMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCC-DMPYPD 1560 +RV +P+ G + + APE + + + DV+S+GI +WEV + PY D Sbjct: 768 SRVLEDDPEAAYTTRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWD 827 Query: 1561 LSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 +S DV A + + R P CP A +M CW RP ++V +++ L Sbjct: 828 MSNQDVIKA-IEEGYRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNMLDKL 881
>Q07496:EPHA4_CHICK Ephrin type-A receptor 4 precursor - Gallus gallus (Chicken)| Length = 986 Score = 109 bits (273), Expect = 4e-23 Identities = 85/295 (28%), Positives = 134/295 (45%), Gaps = 9/295 (3%) Frame = +1 Query: 868 EIDLAKLEIRHVIAQGTYGTVYRGTYD--GQQ---VAVKLLDWGEDGFATEAETTALRTS 1032 EID + ++I VI G +G V G G++ VA+K L G T R Sbjct: 615 EIDASCIKIEKVIGVGEFGEVCSGRLKVPGKREICVAIKTLKAGY--------TDKQRRD 666 Query: 1033 FKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLK 1212 F E ++ + HPN+ G T K PV ++ EY+ G+L Sbjct: 667 FLSEASIMGQFDHPNIIHLEGV---VTKCK-PV--------------MIITEYMENGSLD 708 Query: 1213 QYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGV 1392 +L KN R ++V L + G+ YL VHRD+ N+L+++ K++DFG+ Sbjct: 709 AFLRKNDGRFTVIQLVGMLR-GIGSGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGM 767 Query: 1393 ARVEAQNPK---DMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCC-DMPYPD 1560 +RV +P+ G + + APE + + + DV+S+GI +WEV + PY D Sbjct: 768 SRVLEDDPEAAYTTRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWD 827 Query: 1561 LSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 +S DV A + + R P CP A +M CW RP ++V +++ L Sbjct: 828 MSNQDVIKA-IEEGYRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNMLDKL 881
>Q9FNE1:CRK42_ARATH Cysteine-rich receptor-like protein kinase 42 precursor - Arabidopsis| thaliana (Mouse-ear cress) Length = 651 Score = 109 bits (273), Expect = 4e-23 Identities = 90/307 (29%), Positives = 134/307 (43%), Gaps = 29/307 (9%) Frame = +1 Query: 895 RHVIAQGTYGTVYRGTY-DGQQVAVKLL-----DWGEDGFATEAETTALRTSFKQEVAVW 1056 + ++ QG GTV+ G +G+ VAVK L DW E+ F EV + Sbjct: 318 KKMLGQGGNGTVFLGILPNGKNVAVKRLVFNTRDWVEEFF--------------NEVNLI 363 Query: 1057 HKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYLIKNRR 1236 + H N+ K +G S+ + +V EY+ +L Q+L + Sbjct: 364 SGIQHKNLVKLLGCSIEGPE------------------SLLVYEYVPNKSLDQFLFDESQ 405 Query: 1237 RK-LAYKVVVQLALDLSRGLSYLHSR---KIVHRDVKTENMLLDTQRNLKIADFGVARVE 1404 K L + + + L + GL+YLH +I+HRD+KT N+LLD Q N KIADFG+AR Sbjct: 406 SKVLNWSQRLNIILGTAEGLAYLHGGSPVRIIHRDIKTSNVLLDDQLNPKIADFGLARCF 465 Query: 1405 AQNPKDM-TGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYC-----CDMPYPDLS 1566 + + TG GTLGYMAPE + K DVYSFG+ + E+ C +P Sbjct: 466 GLDKTHLSTGIAGTLGYMAPEYVVRGQLTEKADVYSFGVLVLEIACGTRINAFVPETGHL 525 Query: 1567 FADVSSAVVHQNLRPDIPRCCPSAFANIMRK-------------CWDGNPDKRPDMDEVV 1707 V + L + C F + C +P RP M+EV+ Sbjct: 526 LQRVWNLYTLNRLVEALDPCLKDEFLQVQGSEAEACKVLRVGLLCTQASPSLRPSMEEVI 585 Query: 1708 QLMEALD 1728 +++ D Sbjct: 586 RMLTERD 592
>Q7X8C5:WAKLB_ARATH Wall-associated receptor kinase-like 2 precursor - Arabidopsis| thaliana (Mouse-ear cress) Length = 748 Score = 109 bits (272), Expect = 5e-23 Identities = 91/333 (27%), Positives = 148/333 (44%), Gaps = 21/333 (6%) Frame = +1 Query: 799 LEQQLNKKWSKSNIKSLGPKADWEIDLAKLEIRHVIAQGTYGTVYRGTY-DGQQVAVKLL 975 L+QQL +K + + + E V+ QG GTVY+G DG+ VAVK Sbjct: 387 LKQQLARKEGNVEMSRIFSSHELEKATDNFNKNRVLGQGGQGTVYKGMLVDGRIVAVKRS 446 Query: 976 DWGEDGFATEAETTALRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARAN 1155 ++ E F EV V +++H N+ K +G + T ++PV Sbjct: 447 KAVDEDRVEE---------FINEVVVLAQINHRNIVKLLGCCLET---EVPV-------- 486 Query: 1156 LPARACCVVVEYLAGGTL-KQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRK---IVH 1323 +V E++ G L K+ ++ + ++V + +A++++ LSYLHS I H Sbjct: 487 -------LVYEFVPNGDLCKRLHDESDDYTMTWEVRLHIAIEIAGALSYLHSAASFPIYH 539 Query: 1324 RDVKTENMLLDTQRNLKIADFGVAR-VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCD 1500 RD+KT N+LLD + K++DFG +R V T GT GY+ PE + K D Sbjct: 540 RDIKTTNILLDERNRAKVSDFGTSRSVTIDQTHLTTQVAGTFGYVDPEYFQSSKFTEKSD 599 Query: 1501 VYSFGICLWEVYCCDMPYPDLSFADVSSAVVH---------------QNLRPDIPRCCPS 1635 VYSFG+ L E+ + P + + H ++ + Sbjct: 600 VYSFGVVLVELLTGEKPSSRVRSEENRGLAAHFVEAVKENRVLDIVDDRIKDECNMDQVM 659 Query: 1636 AFANIMRKCWDGNPDKRPDMDEVVQLMEALDTS 1734 + AN+ R+C + KRP+M EV +E + +S Sbjct: 660 SVANLARRCLNRKGKKRPNMREVSIELEMIRSS 692
>P14084:SRC_AVISS Tyrosine-protein kinase transforming protein Src - Avian sarcoma| virus (strain S1) Length = 568 Score = 109 bits (272), Expect = 5e-23 Identities = 86/306 (28%), Positives = 138/306 (45%), Gaps = 3/306 (0%) Frame = +1 Query: 826 SKSNIKSLGPKADWEIDLAKLEIRHVIAQGTYGTVYRGTYDGQ-QVAVKLLDWGEDGFAT 1002 SK + L A WEI L + + QG +G V+ GT++G +VA+K L G Sbjct: 248 SKPQTQGLAKDA-WEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPG------ 300 Query: 1003 EAETTALRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVV 1182 T +F QE V KL H + + A + +V Sbjct: 301 ----TMSPEAFLQEAQVMKKLRHEKLVRLY-------------------AVVSEEPIYIV 337 Query: 1183 VEYLAGGTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQ 1362 EY++ G+L +L + L +V +A ++ G++Y+ VHRD++ N+L+ Sbjct: 338 TEYMSKGSLLDFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGEN 397 Query: 1363 RNLKIADFGVAR-VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYC 1539 K+ADFG+AR +E GA + + APE + K DV+SFGI L E+ Sbjct: 398 LVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTT 457 Query: 1540 CD-MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLM 1716 +PYP + +V V + R P CP + ++M +CW +P++RP + + + Sbjct: 458 KGRVPYPGMVNREVLDQ-VERGYRMPCPPECPESLHDLMCQCWRKDPEERPTFEYLQAFL 516 Query: 1717 EALDTS 1734 E TS Sbjct: 517 EDYFTS 522
>Q25410:MIPR_LYMST Putative molluscan insulin-related peptide(s) receptor precursor -| Lymnaea stagnalis (Great pond snail) Length = 1607 Score = 109 bits (272), Expect = 5e-23 Identities = 90/333 (27%), Positives = 148/333 (44%), Gaps = 27/333 (8%) Frame = +1 Query: 862 DWEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQ--------VAVKLLDWGEDGFATEAETT 1017 +WE+D K+++ + QG++G VY G G + VAVK ++ + + Sbjct: 1029 EWEVDRDKIKLIKELGQGSFGMVYEGVAKGIRDDPNEEIPVAVKTVN--------DRASF 1080 Query: 1018 ALRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLA 1197 + R F +E + +V K +G PA V++E +A Sbjct: 1081 SDRREFLKEATTMKEFHCHHVVKLLGV---------------VSTGQPA---LVIMELMA 1122 Query: 1198 GGTLKQYLIKNRRRKLAYKV-------VVQLALDLSRGLSYLHSRKIVHRDVKTENMLLD 1356 G LK YL +R + V ++Q+A +++ G++YL +K VHRD+ N ++ Sbjct: 1123 LGDLKNYLRGHRPDEDHPGVMPPHLLDILQMAGEIADGMAYLADKKFVHRDLAARNCMVS 1182 Query: 1357 TQRNLKIADFGVARVEAQNPKDMTGATGTL--GYMAPEVLDGKPYNRKCDVYSFGICLWE 1530 +R +KI DFG+ R + G G L +MAPE L + DV+S+G+ +WE Sbjct: 1183 EERTVKIGDFGMTRDIYETDYYRKGGKGMLPVRWMAPESLKDGVFTSLSDVWSYGVVMWE 1242 Query: 1531 -VYCCDMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVV 1707 V PY LS +V + ++P CP+ A +M+ CW P++RP ++ Sbjct: 1243 MVTLAAQPYQGLSNEEVVK-FISDGYIMELPENCPNEMAYLMQHCWAKKPNQRPTFKAII 1301 Query: 1708 Q-LMEALDTS--------KGGGMIPDGQSSGCL 1779 + L+ L S GG DG G L Sbjct: 1302 EYLLPKLKPSFEKVSYFFTSGGGHTDGAGEGTL 1334
>Q07014:LYN_RAT Tyrosine-protein kinase Lyn - Rattus norvegicus (Rat)| Length = 512 Score = 109 bits (272), Expect = 5e-23 Identities = 78/299 (26%), Positives = 136/299 (45%), Gaps = 3/299 (1%) Frame = +1 Query: 856 KADWEIDLAKLEIRHVIAQGTYGTVYRGTYDGQ-QVAVKLLDWGEDGFATEAETTALRTS 1032 K WEI +++ + G +G V+ G Y+ +VAVK L G T + Sbjct: 237 KDAWEIPRESIKLVKKLGAGQFGEVWMGYYNNSTKVAVKTLKPG----------TMSAQA 286 Query: 1033 FKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLK 1212 F +E + L H + + + I + E++A G+L Sbjct: 287 FLEEANLMKTLQHDKLVRLYAVVTKEEPIYI------------------ITEFMAKGSLL 328 Query: 1213 QYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGV 1392 +L + K+ ++ + ++ G++Y+ + +HRD++ N+L+ KIADFG+ Sbjct: 329 DFLKSDEGSKVLLPKLIDFSAQIAEGMAYIERKNYIHRDLRAANVLVSESLMCKIADFGL 388 Query: 1393 ARVEAQNP-KDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCC-DMPYPDLS 1566 ARV N GA + + APE ++ + K DV+SFGI L+E+ +PYP + Sbjct: 389 ARVIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLYEIVTYGKIPYPGRT 448 Query: 1567 FADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDTSKGG 1743 ADV +A + Q R CP +IM+ CW + ++RP D + +++ T+ G Sbjct: 449 NADVMTA-LSQGYRMPRMENCPDELYDIMKMCWKESAEERPTFDYLQSVLDDFYTATEG 506
>P07948:LYN_HUMAN Tyrosine-protein kinase Lyn - Homo sapiens (Human)| Length = 512 Score = 109 bits (272), Expect = 5e-23 Identities = 78/299 (26%), Positives = 135/299 (45%), Gaps = 3/299 (1%) Frame = +1 Query: 856 KADWEIDLAKLEIRHVIAQGTYGTVYRGTYDGQ-QVAVKLLDWGEDGFATEAETTALRTS 1032 K WEI +++ + G +G V+ G Y+ +VAVK L G T + Sbjct: 237 KDAWEIPRESIKLVKRLGAGQFGEVWMGYYNNSTKVAVKTLKPG----------TMSVQA 286 Query: 1033 FKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLK 1212 F +E + L H + + + I + EY+A G+L Sbjct: 287 FLEEANLMKTLQHDKLVRLYAVVTREEPIYI------------------ITEYMAKGSLL 328 Query: 1213 QYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGV 1392 +L + K+ ++ + ++ G++Y+ + +HRD++ N+L+ KIADFG+ Sbjct: 329 DFLKSDEGGKVLLPKLIDFSAQIAEGMAYIERKNYIHRDLRAANVLVSESLMCKIADFGL 388 Query: 1393 ARVEAQNP-KDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCC-DMPYPDLS 1566 ARV N GA + + APE ++ + K DV+SFGI L+E+ +PYP + Sbjct: 389 ARVIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLYEIVTYGKIPYPGRT 448 Query: 1567 FADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDTSKGG 1743 ADV +A+ P + CP +IM+ CW ++RP D + +++ T+ G Sbjct: 449 NADVMTALSQGYRMPRVEN-CPDELYDIMKMCWKEKAEERPTFDYLQSVLDDFYTATEG 506
>P15127:INSR_RAT Insulin receptor precursor - Rattus norvegicus (Rat)| Length = 1383 Score = 109 bits (272), Expect = 5e-23 Identities = 84/305 (27%), Positives = 136/305 (44%), Gaps = 19/305 (6%) Frame = +1 Query: 862 DWEIDLAKLEIRHVIAQGTYGTVYRGTYDG-------QQVAVKLLDWGEDGFATEAETTA 1020 +WE+ K+ + + QG++G VY G +VAVK ++ E+ + Sbjct: 1016 EWEVPREKITLLRELGQGSFGMVYEGNAKDIIKGEVETRVAVKTVN--------ESASLR 1067 Query: 1021 LRTSFKQEVAVWHKLSHPNVTKFVGA-SMGTTDLKIPVNDNGARANLPARACCVVVEYLA 1197 R F E +V + +V + +G S G L VV+E +A Sbjct: 1068 ERIEFLNEASVMKGFTCHHVVRLLGVVSKGQPTL-------------------VVMELMA 1108 Query: 1198 GGTLKQYLIKNR--------RRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLL 1353 G LK +L R R + ++Q+ +++ G++YL+++K VHRD+ N ++ Sbjct: 1109 HGDLKSHLRSLRPDAENNPGRPPPTLQEMIQMTAEIADGMAYLNAKKFVHRDLAARNCMV 1168 Query: 1354 DTQRNLKIADFGVARVEAQNPKDMTGATGTL--GYMAPEVLDGKPYNRKCDVYSFGICLW 1527 +KI DFG+ R + G G L +M+PE L + D++SFG+ LW Sbjct: 1169 AHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTASSDMWSFGVVLW 1228 Query: 1528 EV-YCCDMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEV 1704 E+ + PY LS V V+ D P CP ++MR CW NP RP E+ Sbjct: 1229 EITSLAEQPYQGLSNEQVLKFVMDGGYL-DPPDNCPERLTDLMRMCWQFNPKMRPTFLEI 1287 Query: 1705 VQLME 1719 V L++ Sbjct: 1288 VNLLK 1292
>Q922K9:FRK_MOUSE Tyrosine-protein kinase FRK - Mus musculus (Mouse)| Length = 512 Score = 109 bits (272), Expect = 5e-23 Identities = 78/284 (27%), Positives = 133/284 (46%), Gaps = 6/284 (2%) Frame = +1 Query: 865 WEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQ-VAVKLLDWGEDGFATEAETTALRTSFKQ 1041 WEID +++ + G +G V+ G ++ VAVK L G F + Sbjct: 234 WEIDRNSIQLLKRLGSGQFGEVWEGLWNNTTPVAVKTLKPGSMD----------PNDFLR 283 Query: 1042 EVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYL 1221 E + L HP + + L+ P+ ++ E + G+L++YL Sbjct: 284 EAQIMKSLRHPKLIQLYAVCT----LEDPIY--------------IITELMRHGSLQEYL 325 Query: 1222 IKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGVARV 1401 + K+ V +A ++ G++YL S+ +HRD+ N+L+ K+ADFG+ARV Sbjct: 326 QNDGGSKIHLIQQVDMAAQVASGMAYLESQNYIHRDLAARNVLVGEHNIYKVADFGLARV 385 Query: 1402 EAQNPKDMTGATGTL----GYMAPEVLDGKPYNRKCDVYSFGICLWEVYCC-DMPYPDLS 1566 + +D+ + + + APE + ++ K DV+SFGI L+E+ MPY ++ Sbjct: 386 FKVDNEDIYESKHEIKLPVKWTAPEAIRTNKFSIKSDVWSFGILLYEIITYGKMPYSGMT 445 Query: 1567 FADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMD 1698 A V ++ QN R P CP F +IM +CW+ P +RP + Sbjct: 446 GAQVIQ-MLSQNYRLPQPSNCPQQFYSIMLECWNVEPKQRPTFE 488
>O42127:FGFR3_XENLA Fibroblast growth factor receptor 3 precursor - Xenopus laevis| (African clawed frog) Length = 802 Score = 109 bits (272), Expect = 5e-23 Identities = 89/328 (27%), Positives = 148/328 (45%), Gaps = 28/328 (8%) Frame = +1 Query: 832 SNIKSLGPKAD--WEIDLAKLEIRHVIAQGTYGTVYRGTYDG---------QQVAVKLLD 978 +N+ LG D WE+ ++L + + +G +G V G VAVK+L Sbjct: 442 ANVSELGLPLDPKWELLRSRLTLGKPLGEGCFGQVVMAEAIGIDKERPNKPATVAVKMLK 501 Query: 979 WGEDGFATEAETTALRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANL 1158 +D AT+ + + L + + + H N+ +GA L Sbjct: 502 --DD--ATDKDLSDLVSEMEMMKMIG---KHKNIINLLGACTQDGPLY------------ 542 Query: 1159 PARACCVVVEYLAGGTLKQYLIKNR--------------RRKLAYKVVVQLALDLSRGLS 1296 V+VEY + G+L++YL R +L +K +V A ++RG+ Sbjct: 543 ------VLVEYASKGSLREYLKARRPPGMDYSFDACKIPAEQLTFKDLVSCAYQVARGME 596 Query: 1297 YLHSRKIVHRDVKTENMLLDTQRNLKIADFGVAR--VEAQNPKDMTGATGTLGYMAPEVL 1470 YL S+K +HRD+ N+L+ +KIADFG+AR K T + +MAPE L Sbjct: 597 YLASQKCIHRDLAARNVLVTDDNVMKIADFGLARDIHNIDYYKKTTNGRLPVKWMAPEAL 656 Query: 1471 DGKPYNRKCDVYSFGICLWEVYCC-DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFAN 1647 + Y DV+S+G+ LWE++ PYP + ++ ++ + R D P C Sbjct: 657 FDRIYTHHSDVWSYGVLLWEIFTLGGSPYPGIPVEELFK-LLKEGHRMDKPANCTHELYM 715 Query: 1648 IMRKCWDGNPDKRPDMDEVVQLMEALDT 1731 IMR+CW P +RP ++V+ ++ + T Sbjct: 716 IMRECWHAVPSQRPAFKQLVEDLDRVLT 743
>P21804:FGFR1_CHICK Basic fibroblast growth factor receptor 1 precursor - Gallus gallus| (Chicken) Length = 819 Score = 109 bits (272), Expect = 5e-23 Identities = 84/313 (26%), Positives = 140/313 (44%), Gaps = 26/313 (8%) Frame = +1 Query: 865 WEIDLAKLEIRHVIAQGTYGTVYRGTYDG---------QQVAVKLLDWGEDGFATEAETT 1017 WE+ +L + + +G +G V G +VAVK+L ATE + + Sbjct: 469 WELPRDRLILGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLK----SDATEKDLS 524 Query: 1018 ALRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLA 1197 L + + + H N+ +GA L V+VEY + Sbjct: 525 DLISEMEMMKMIG---KHKNIINLLGACTQDGPLY------------------VIVEYAS 563 Query: 1198 GGTLKQYLIKNR--------------RRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVK 1335 G L++YL R +L++K +V A ++RG+ YL S+K +HRD+ Sbjct: 564 KGNLREYLQARRPPGMEYCYNPTRIPEEQLSFKDLVSCAYQVARGMEYLASKKCIHRDLA 623 Query: 1336 TENMLLDTQRNLKIADFGVAR--VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYS 1509 N+L+ +KIADFG+AR K T + +MAPE L + Y + DV+S Sbjct: 624 ARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWS 683 Query: 1510 FGICLWEVYCC-DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKR 1686 FG+ LWE++ PYP + ++ ++ + R D P C + +MR CW P +R Sbjct: 684 FGVLLWEIFTLGGSPYPGVPVEELFK-LLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQR 742 Query: 1687 PDMDEVVQLMEAL 1725 P ++V+ ++ + Sbjct: 743 PTFKQLVEDLDRI 755
>P54760:EPHB4_HUMAN Ephrin type-B receptor 4 precursor - Homo sapiens (Human)| Length = 987 Score = 109 bits (272), Expect = 5e-23 Identities = 82/298 (27%), Positives = 138/298 (46%), Gaps = 12/298 (4%) Frame = +1 Query: 868 EIDLAKLEIRHVIAQGTYGTVYRGTYDGQQ-----VAVKLLDWGEDGFATEAETTALRTS 1032 EID++ ++I VI G +G V RG VA+K L G T R Sbjct: 609 EIDVSYVKIEEVIGAGEFGEVCRGRLKAPGKKESCVAIKTLKGGY--------TERQRRE 660 Query: 1033 FKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLK 1212 F E ++ + HPN+ + G + +PV ++ E++ G L Sbjct: 661 FLSEASIMGQFEHPNIIRLEGVVTNS----MPV--------------MILTEFMENGALD 702 Query: 1213 QYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGV 1392 +L N + ++V L ++ G+ YL VHRD+ N+L+++ K++DFG+ Sbjct: 703 SFLRLNDGQFTVIQLVGMLR-GIASGMRYLAEMSYVHRDLAARNILVNSNLVCKVSDFGL 761 Query: 1393 ARVEAQNPKDMTGATGTLG------YMAPEVLDGKPYNRKCDVYSFGICLWEVYCC-DMP 1551 +R +N D T T +LG + APE + + + D +S+GI +WEV + P Sbjct: 762 SRFLEENSSDPT-YTSSLGGKIPIRWTAPEAIAFRKFTSASDAWSYGIVMWEVMSFGERP 820 Query: 1552 YPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 Y D+S DV +A + Q+ R P CP++ +M CW + + RP +VV ++ + Sbjct: 821 YWDMSNQDVINA-IEQDYRLPPPPDCPTSLHQLMLDCWQKDRNARPRFPQVVSALDKM 877
>Q61772:EPHA7_MOUSE Ephrin type-A receptor 7 precursor - Mus musculus (Mouse)| Length = 998 Score = 109 bits (272), Expect = 5e-23 Identities = 82/310 (26%), Positives = 141/310 (45%), Gaps = 9/310 (2%) Frame = +1 Query: 868 EIDLAKLEIRHVIAQGTYGTVYRGTYD--GQQ---VAVKLLDWGEDGFATEAETTALRTS 1032 E+D + ++I VI G +G V G GQ+ VA+K L G T R Sbjct: 627 ELDASCIKIERVIGAGEFGEVCSGRLKLPGQRDVAVAIKTLKVGY--------TEKQRRD 678 Query: 1033 FKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLK 1212 F E ++ + HPNV G + +V+E++ G L Sbjct: 679 FLCEASIMGQFDHPNVVHLEGVVTR------------------GKPVMIVIEFMENGALD 720 Query: 1213 QYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGV 1392 +L K+ + ++V L ++ G+ YL VHRD+ N+L+++ K++DFG+ Sbjct: 721 AFLRKHDGQFTVIQLVGMLR-GIAAGMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGL 779 Query: 1393 ARVEAQNPKDMTGATG---TLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCC-DMPYPD 1560 +RV +P+ + TG + + APE + + + DV+S+GI +WEV + PY D Sbjct: 780 SRVIEDDPEAVYTTTGGKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWD 839 Query: 1561 LSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDTSKG 1740 +S DV A + + R P CP+ +M CW + +RP +++V +++ + + Sbjct: 840 MSNQDVIKA-IEEGYRLPAPMDCPAGLHQLMLDCWQKDRAERPKFEQIVGILDKMIRNPS 898 Query: 1741 GGMIPDGQSS 1770 P G S Sbjct: 899 SLKTPLGTCS 908
>O42422:EPHA7_CHICK Ephrin type-A receptor 7 precursor - Gallus gallus (Chicken)| Length = 993 Score = 109 bits (272), Expect = 5e-23 Identities = 82/310 (26%), Positives = 140/310 (45%), Gaps = 9/310 (2%) Frame = +1 Query: 868 EIDLAKLEIRHVIAQGTYGTVYRGTYD--GQQ---VAVKLLDWGEDGFATEAETTALRTS 1032 E+D + ++I VI G +G V G G++ VA+K L G T R Sbjct: 622 ELDASCIKIERVIGAGEFGEVCSGRLKLPGKRDVAVAIKTLKVGY--------TEKQRRD 673 Query: 1033 FKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLK 1212 F E ++ + HPNV G + +V+EY+ G L Sbjct: 674 FLCEASIMGQFDHPNVVHLEGVVTR------------------GKPVMIVIEYMENGALD 715 Query: 1213 QYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGV 1392 +L K+ + ++V L ++ G+ YL VHRD+ N+L+++ K++DFG+ Sbjct: 716 AFLRKHDGQFTVIQLVGMLR-GIAAGMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGL 774 Query: 1393 ARVEAQNPKDMTGATG---TLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCC-DMPYPD 1560 +RV +P+ + TG + + APE + + + DV+S+GI +WEV + PY D Sbjct: 775 SRVIEDDPEAVYTTTGGKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWD 834 Query: 1561 LSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDTSKG 1740 +S DV A + + R P CP+ +M CW +RP +++V +++ + + Sbjct: 835 MSNQDVIKA-IEEGYRLPAPMDCPAGLHQLMLDCWQKERGERPKFEQIVGILDKMIRNPN 893 Query: 1741 GGMIPDGQSS 1770 P G S Sbjct: 894 SLKTPLGTCS 903
>Q9LMN6:WAK4_ARATH Wall-associated receptor kinase 4 precursor - Arabidopsis thaliana| (Mouse-ear cress) Length = 738 Score = 108 bits (271), Expect = 7e-23 Identities = 88/305 (28%), Positives = 145/305 (47%), Gaps = 26/305 (8%) Frame = +1 Query: 901 VIAQGTYGTVYRGTY-DGQQVAVKLLDWGEDGFATEAETTALRTSFKQEVAVWHKLSHPN 1077 ++ QG GTVY+G D VA+K G++ + F EV V +++H N Sbjct: 415 ILGQGGQGTVYKGILPDNSIVAIKKARLGDNSQVEQ---------FINEVLVLSQINHRN 465 Query: 1078 VTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYLIKNR-RRKLAYK 1254 V K +G + T ++P+ +V E+++ GTL +L + L ++ Sbjct: 466 VVKLLGCCLET---EVPL---------------LVYEFISSGTLFDHLHGSMFDSSLTWE 507 Query: 1255 VVVQLALDLSRGLSYLHSRK---IVHRDVKTENMLLDTQRNLKIADFGVARVEAQNPKDM 1425 +++A++++ L+YLHS I+HRD+KT N+LLD K+ADFG +R+ + +D+ Sbjct: 508 HRLRMAVEIAGTLAYLHSSASIPIIHRDIKTANILLDENLTAKVADFGASRLIPMDKEDL 567 Query: 1426 -TGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEV------YCCDMPYPDLSFAD--- 1575 T GTLGY+ PE + N K DVYSFG+ L E+ C + P Sbjct: 568 ATMVQGTLGYLDPEYYNTGLLNEKSDVYSFGVVLMELLSGQKALCFERPQTSKHIVSYFA 627 Query: 1576 -----------VSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEA 1722 + V+++N + +I + A I +C ++RP M EV +EA Sbjct: 628 SATKENRLHEIIDGQVMNENNQREIQKA-----ARIAVECTRLTGEERPGMKEVAAELEA 682 Query: 1723 LDTSK 1737 L +K Sbjct: 683 LRVTK 687
>P31693:SRC_RSVPA Tyrosine-protein kinase transforming protein Src - Rous sarcoma virus| (strain PA101T) Length = 523 Score = 108 bits (271), Expect = 7e-23 Identities = 86/303 (28%), Positives = 140/303 (46%), Gaps = 4/303 (1%) Frame = +1 Query: 826 SKSNIKSLGPKADWEIDLAKLEIRHVIAQGTYGTVYRGTYDGQ-QVAVKLLDWGEDGFAT 1002 SK + L A WEI L + + QG +G V+ GT++G +VA+K L G Sbjct: 245 SKPQTQGLAKDA-WEIPRESLRLEVKLGQGYFGEVWMGTWNGTTRVAIKTLKPG------ 297 Query: 1003 EAETTALRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVV 1182 T +F QE V KL H + + A + +V Sbjct: 298 ----TMSPEAFLQEAQVMKKLRHEKLVQLY-------------------AMVSEEPIYIV 334 Query: 1183 VEYLAGGTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQ 1362 +EY++ G+L +L + L +V++A ++ G++Y+ VHRD++ N+L+ Sbjct: 335 IEYMSKGSLLDFLKGEMGKYLRLPQLVEMAAQIASGMAYVERMNYVHRDLRAANILVGEN 394 Query: 1363 RNLKIADFGVAR-VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYC 1539 K+ADFG+AR +E GA + + APE + K DV+SFGI L E+ Sbjct: 395 LVCKVADFGLARLIEDNEYTARPGARFPVKWTAPEAALYGRFTIKSDVWSFGILLTELTT 454 Query: 1540 CD-MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEV-VQL 1713 +PYP + +V V + R P CP + ++M +CW +P++RP + + QL Sbjct: 455 KGRVPYPGMVNGEVLDR-VERGYRMPCPPECPESLHDLMCQCWRKDPEERPTFEYLQAQL 513 Query: 1714 MEA 1722 + A Sbjct: 514 LPA 516
>P00523:SRC_CHICK Proto-oncogene tyrosine-protein kinase Src - Gallus gallus (Chicken)| Length = 533 Score = 108 bits (271), Expect = 7e-23 Identities = 86/306 (28%), Positives = 138/306 (45%), Gaps = 3/306 (0%) Frame = +1 Query: 826 SKSNIKSLGPKADWEIDLAKLEIRHVIAQGTYGTVYRGTYDGQ-QVAVKLLDWGEDGFAT 1002 SK + L A WEI L + + QG +G V+ GT++G +VA+K L G Sbjct: 248 SKPQTQGLAKDA-WEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPG------ 300 Query: 1003 EAETTALRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVV 1182 T +F QE V KL H + + A + +V Sbjct: 301 ----TMSPEAFLQEAQVMKKLRHEKLVQLY-------------------AVVSEEPIYIV 337 Query: 1183 VEYLAGGTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQ 1362 EY++ G+L +L + L +V +A ++ G++Y+ VHRD++ N+L+ Sbjct: 338 TEYMSKGSLLDFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGEN 397 Query: 1363 RNLKIADFGVAR-VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYC 1539 K+ADFG+AR +E GA + + APE + K DV+SFGI L E+ Sbjct: 398 LVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTT 457 Query: 1540 CD-MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLM 1716 +PYP + +V V + R P CP + ++M +CW +P++RP + + + Sbjct: 458 KGRVPYPGMVNREVLDQ-VERGYRMPCPPECPESLHDLMCQCWRKDPEERPTFEYLQAFL 516 Query: 1717 EALDTS 1734 E TS Sbjct: 517 EDYFTS 522
>P15054:SRC_AVIS2 Tyrosine-protein kinase transforming protein Src - Avian sarcoma| virus (strain PR2257) Length = 587 Score = 108 bits (271), Expect = 7e-23 Identities = 86/306 (28%), Positives = 138/306 (45%), Gaps = 3/306 (0%) Frame = +1 Query: 826 SKSNIKSLGPKADWEIDLAKLEIRHVIAQGTYGTVYRGTYDGQ-QVAVKLLDWGEDGFAT 1002 SK + L A WEI L + + QG +G V+ GT++G +VA+K L G Sbjct: 248 SKPQTQGLAKDA-WEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPG------ 300 Query: 1003 EAETTALRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVV 1182 T +F QE V KL H + + A + +V Sbjct: 301 ----TMSPEAFLQEAQVMKKLRHEKLVQLY-------------------AVVSEEPIYIV 337 Query: 1183 VEYLAGGTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQ 1362 EY++ G+L +L + L +V +A ++ G++Y+ VHRD++ N+L+ Sbjct: 338 TEYMSKGSLLDFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGEN 397 Query: 1363 RNLKIADFGVAR-VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYC 1539 K+ADFG+AR +E GA + + APE + K DV+SFGI L E+ Sbjct: 398 LVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTT 457 Query: 1540 CD-MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLM 1716 +PYP + +V V + R P CP + ++M +CW +P++RP + + + Sbjct: 458 KGRVPYPGMVNREVLDQ-VERGYRMPCPPECPESLHDLMCQCWRKDPEERPTFEYLQAFL 516 Query: 1717 EALDTS 1734 E TS Sbjct: 517 EDYFTS 522
>P25911:LYN_MOUSE Tyrosine-protein kinase Lyn - Mus musculus (Mouse)| Length = 512 Score = 108 bits (271), Expect = 7e-23 Identities = 79/299 (26%), Positives = 135/299 (45%), Gaps = 3/299 (1%) Frame = +1 Query: 856 KADWEIDLAKLEIRHVIAQGTYGTVYRGTYDGQ-QVAVKLLDWGEDGFATEAETTALRTS 1032 K WEI +++ + G +G V+ G Y+ +VAVK L G T + Sbjct: 237 KDAWEIPRESIKLVKKLGAGQFGEVWMGYYNNSTKVAVKTLKPG----------TMSVQA 286 Query: 1033 FKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLK 1212 F +E + L H + + + I + E++A G+L Sbjct: 287 FLEEANLMKTLQHDKLVRLYAVVTKEEPIYI------------------ITEFMAKGSLL 328 Query: 1213 QYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGV 1392 +L + K+ ++ + ++ G++Y+ + +HRD++ N+L+ KIADFG+ Sbjct: 329 DFLKSDEGGKVLLPKLIDFSAQIAEGMAYIERKNYIHRDLRAANVLVSESLMCKIADFGL 388 Query: 1393 ARVEAQNP-KDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCC-DMPYPDLS 1566 ARV N GA + + APE ++ + K DV+SFGI L+E+ +PYP + Sbjct: 389 ARVIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLYEIVTYGKIPYPGRT 448 Query: 1567 FADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDTSKGG 1743 ADV SA + Q R CP +IM+ CW ++RP D + +++ T+ G Sbjct: 449 NADVMSA-LSQGYRMPRMENCPDELYDIMKMCWKEKAEERPTFDYLQSVLDDFYTATEG 506
>P39688:FYN_MOUSE Proto-oncogene tyrosine-protein kinase Fyn - Mus musculus (Mouse)| Length = 537 Score = 108 bits (271), Expect = 7e-23 Identities = 81/295 (27%), Positives = 135/295 (45%), Gaps = 3/295 (1%) Frame = +1 Query: 844 SLGPKADWEIDLAKLEIRHVIAQGTYGTVYRGTYDGQ-QVAVKLLDWGEDGFATEAETTA 1020 S+ K WEI L++ + G +G V+ GT++G +VA+K L G T Sbjct: 257 SVKTKDVWEIPRESLQLIKRLGNGQFGEVWLGTWNGNTKVAIKTLKPG----------TM 306 Query: 1021 LRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAG 1200 SF +E + KL H + + A + +V EY++ Sbjct: 307 SPESFLEEAQIMKKLKHDKLVQLY-------------------AVVSEEPIYIVTEYMSK 347 Query: 1201 GTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIA 1380 G+L +L R L +V +A ++ G++Y+ +HRD+++ N+L+ KIA Sbjct: 348 GSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIA 407 Query: 1381 DFGVAR-VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCD-MPY 1554 DFG+AR +E GA + + APE + K DV+SFGI L E+ +PY Sbjct: 408 DFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPY 467 Query: 1555 PDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 1719 P ++ +V V + R P+ CP + +M CW +P++RP + + +E Sbjct: 468 PGMNNREVLEQ-VERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQGFLE 521
>P06241:FYN_HUMAN Proto-oncogene tyrosine-protein kinase Fyn - Homo sapiens (Human)| Length = 537 Score = 108 bits (271), Expect = 7e-23 Identities = 81/295 (27%), Positives = 134/295 (45%), Gaps = 3/295 (1%) Frame = +1 Query: 844 SLGPKADWEIDLAKLEIRHVIAQGTYGTVYRGTYDGQ-QVAVKLLDWGEDGFATEAETTA 1020 S+ K WEI L++ + G +G V+ GT++G +VA+K L G T Sbjct: 257 SVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNGNTKVAIKTLKPG----------TM 306 Query: 1021 LRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAG 1200 SF +E + KL H + + A + +V EY+ Sbjct: 307 SPESFLEEAQIMKKLKHDKLVQLY-------------------AVVSEEPIYIVTEYMNK 347 Query: 1201 GTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIA 1380 G+L +L R L +V +A ++ G++Y+ +HRD+++ N+L+ KIA Sbjct: 348 GSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIA 407 Query: 1381 DFGVAR-VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCD-MPY 1554 DFG+AR +E GA + + APE + K DV+SFGI L E+ +PY Sbjct: 408 DFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPY 467 Query: 1555 PDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 1719 P ++ +V V + R P+ CP + +M CW +P++RP + + +E Sbjct: 468 PGMNNREVLEQ-VERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQSFLE 521
>P22182:FGFR1_XENLA Fibroblast growth factor receptor 1 precursor - Xenopus laevis| (African clawed frog) Length = 812 Score = 108 bits (271), Expect = 7e-23 Identities = 91/337 (27%), Positives = 148/337 (43%), Gaps = 27/337 (8%) Frame = +1 Query: 865 WEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFATEAETTALRTSFKQE 1044 WE+ +L + + +G +G V G LD + T+ L++ E Sbjct: 465 WEVARDRLILGKPLGEGCFGQVVMAEAIG-------LDKEKPNKVTKVAVKMLKSD-ASE 516 Query: 1045 VAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYLI 1224 + +S + K +G +L +G V+VEY + G L++YL Sbjct: 517 KDLSDLISEMEMMKMIGKHKNIINLLGACTQDGP--------LYVIVEYTSKGNLREYLR 568 Query: 1225 KNRR--------------RKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQ 1362 R + L++K +V A ++RG+ YL S+K +HRD+ N+L+ Sbjct: 569 ARRPPAMEYCYNPTCVPDQLLSFKDLVSCAYQVARGMDYLASKKCIHRDLAARNVLVTED 628 Query: 1363 RNLKIADFGVAR--VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVY 1536 +KIADFG+AR K T + +MAPE L + Y + DV+SFG+ LWE++ Sbjct: 629 NIMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIF 688 Query: 1537 CC-DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRP-------D 1692 PYP + ++ ++ + R D P C + +M+ CW P +RP D Sbjct: 689 TLGGSPYPGVPMEELFK-LLKEGHRMDKPTNCTNELYMMMKDCWHAMPSQRPTFNQLVED 747 Query: 1693 MDEVVQL---MEALDTSKGGGMIPDGQSSGCLCFTRA 1794 +D ++ L E LD S +P Q S C TR+ Sbjct: 748 LDRILALSSNQEYLDLS-----MPVNQYSPCFPDTRS 779
>P54757:EPHA5_RAT Ephrin type-A receptor 5 precursor - Rattus norvegicus (Rat)| Length = 1005 Score = 108 bits (271), Expect = 7e-23 Identities = 80/295 (27%), Positives = 135/295 (45%), Gaps = 9/295 (3%) Frame = +1 Query: 868 EIDLAKLEIRHVIAQGTYGTVYRGTYD--GQQ---VAVKLLDWGEDGFATEAETTALRTS 1032 EI+ + + I VI G +G V G G++ VA K L G T R Sbjct: 671 EIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVATKTLKVGY--------TEKQRRD 722 Query: 1033 FKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLK 1212 F E ++ + HPN+ G ++ +V EY+ G+L Sbjct: 723 FLSEASIMGQFDHPNIIHLEGVVT------------------KSKPVMIVTEYMENGSLD 764 Query: 1213 QYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGV 1392 +L KN + ++V L ++ G+ YL VHRD+ N+L+++ K++DFG+ Sbjct: 765 TFLKKNDGQFTVIQLVGMLR-GIAAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGL 823 Query: 1393 ARVEAQNPK---DMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCC-DMPYPD 1560 +RV +P+ G + + APE + + + DV+S+GI +WEV + PY + Sbjct: 824 SRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWE 883 Query: 1561 LSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 ++ DV A V + R P CP+A +M CW + + RP D++V +++ L Sbjct: 884 MTNQDVIKA-VEEGYRLPSPMDCPAALYQLMLDCWQKDRNSRPKFDDIVNMLDKL 937
>Q03145:EPHA2_MOUSE Ephrin type-A receptor 2 precursor - Mus musculus (Mouse)| Length = 977 Score = 108 bits (271), Expect = 7e-23 Identities = 75/285 (26%), Positives = 130/285 (45%), Gaps = 10/285 (3%) Frame = +1 Query: 901 VIAQGTYGTVYRGTYDGQQ------VAVKLLDWGEDGFATEAETTALRTSFKQEVAVWHK 1062 VI G +G VY+GT VA+K L G T R F E ++ + Sbjct: 619 VIGAGEFGEVYKGTLKASSGKKEIPVAIKTLKAGY--------TEKQRVDFLSEASIMGQ 670 Query: 1063 LSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYLIKNRRRK 1242 SH N+ G + I + EY+ G L ++L + + + Sbjct: 671 FSHHNIIPLEGVVSKYKPMMI------------------ITEYMENGALDKFL-REKDGE 711 Query: 1243 LAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGVARVEAQNPK- 1419 + +V + ++ G+ YL + VHRD+ N+L+++ K++DFG++RV +P+ Sbjct: 712 FSVLQLVGMLRGIASGMKYLANMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEA 771 Query: 1420 --DMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCC-DMPYPDLSFADVSSAV 1590 +G + + APE + + + DV+S+GI +WEV + PY +LS +V A Sbjct: 772 TYTTSGGKIPIRWTAPEAISYRKFTSASDVWSYGIVMWEVMTYGERPYWELSNHEVMKA- 830 Query: 1591 VHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 ++ R P CPSA +M +CW +RP ++V +++ L Sbjct: 831 INDGFRLPTPMDCPSAIYQLMMQCWQQERSRRPKFADIVSILDKL 875
>P42681:TXK_HUMAN Tyrosine-protein kinase TXK - Homo sapiens (Human)| Length = 527 Score = 108 bits (270), Expect = 9e-23 Identities = 81/285 (28%), Positives = 131/285 (45%), Gaps = 3/285 (1%) Frame = +1 Query: 865 WEIDLAKLEIRHVIAQGTYGTVYRGTYDGQ-QVAVKLLDWGEDGFATEAETTALRTSFKQ 1041 WEID ++L I G +G V+ G + QVA+K ++ +G +E + F + Sbjct: 264 WEIDPSELAFIKEIGSGQFGVVHLGEWRSHIQVAIKAIN---EGSMSEED-------FIE 313 Query: 1042 EVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYL 1221 E V KLSH + + G + L I V E++ G L YL Sbjct: 314 EAKVMMKLSHSKLVQLYGVCIQRKPLYI------------------VTEFMENGCLLNYL 355 Query: 1222 IKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGVAR- 1398 +N+ KL ++++ + D+ G+ YL +HRD+ N L+ + +KI+DFG+ R Sbjct: 356 RENKG-KLRKEMLLSVCQDICEGMEYLERNGYIHRDLAARNCLVSSTCIVKISDFGMTRY 414 Query: 1399 VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYC-CDMPYPDLSFAD 1575 V GA + + PEV Y+ K DV+SFG+ +WEV+ MP+ + S Sbjct: 415 VLDDEYVSSFGAKFPIKWSPPEVFLFNKYSSKSDVWSFGVLMWEVFTEGKMPFENKSNLQ 474 Query: 1576 VSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQ 1710 V A + + R P P + +M CW P+ RP E+++ Sbjct: 475 VVEA-ISEGFRLYRPHLAPMSIYEVMYSCWHEKPEGRPTFAELLR 518
>P42690:SRK4_SPOLA Tyrosine-protein kinase isoform SRK4 - Spongilla lacustris| (Freshwater sponge) Length = 506 Score = 108 bits (270), Expect = 9e-23 Identities = 84/299 (28%), Positives = 134/299 (44%), Gaps = 4/299 (1%) Frame = +1 Query: 862 DWEIDLAKLEIRHVIAQGTYGTVYRGTYDGQ-QVAVKLLDWGEDGFATEAETTALRTSFK 1038 +WEI+ ++++ + G +G V+ G ++G VAVK L G T F Sbjct: 232 EWEIEKKQIKLLRGLGAGQFGEVWEGLWNGTTSVAVKTLKPG----------TMSIEEFL 281 Query: 1039 QEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQY 1218 +E ++ +L HP + + + I V E + G+L +Y Sbjct: 282 EEASIMKQLRHPKLIQLYAVCTKEEPIYI------------------VTELMKHGSLLEY 323 Query: 1219 LIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGVAR 1398 L + R L +V + ++ G+SYL + +HRD+ N+L+ + K+ADFG+AR Sbjct: 324 L-RGDGRSLKLPDLVDMCSQVASGMSYLEQQNYIHRDLAARNILVGEHKICKVADFGLAR 382 Query: 1399 V-EAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCD-MPYPDLSFA 1572 V + + + GA + + APE + K DV+SFGI L+EV PYP ++ A Sbjct: 383 VIDEEIYEAKLGAKFPIKWTAPEAAMYSRFTIKSDVWSFGIVLYEVITYGRFPYPGMTNA 442 Query: 1573 DVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVV-QLMEALDTSKGGG 1746 V + Q+ R P CP IM CW +P RP + + QL E T G Sbjct: 443 QVLEQ-IQQSYRMPRPMGCPEKLYAIMMDCWREDPASRPTFETLSWQLEEFFTTGDDAG 500
>P12931:SRC_HUMAN Proto-oncogene tyrosine-protein kinase Src - Homo sapiens (Human)| Length = 536 Score = 108 bits (270), Expect = 9e-23 Identities = 86/306 (28%), Positives = 137/306 (44%), Gaps = 3/306 (0%) Frame = +1 Query: 826 SKSNIKSLGPKADWEIDLAKLEIRHVIAQGTYGTVYRGTYDGQ-QVAVKLLDWGEDGFAT 1002 SK + L A WEI L + + QG +G V+ GT++G +VA+K L G Sbjct: 251 SKPQTQGLAKDA-WEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPG------ 303 Query: 1003 EAETTALRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVV 1182 T +F QE V KL H + + A + +V Sbjct: 304 ----TMSPEAFLQEAQVMKKLRHEKLVQLY-------------------AVVSEEPIYIV 340 Query: 1183 VEYLAGGTLKQYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQ 1362 EY++ G+L +L + L +V +A ++ G++Y+ VHRD++ N+L+ Sbjct: 341 TEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGEN 400 Query: 1363 RNLKIADFGVAR-VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYC 1539 K+ADFG+AR +E GA + + APE + K DV+SFGI L E+ Sbjct: 401 LVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTT 460 Query: 1540 CD-MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLM 1716 +PYP + +V V + R P CP + ++M +CW P++RP + + + Sbjct: 461 KGRVPYPGMVNREVLDQ-VERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFL 519 Query: 1717 EALDTS 1734 E TS Sbjct: 520 EDYFTS 525
>P13116:SRC2_XENLA Tyrosine-protein kinase Src-2 - Xenopus laevis (African clawed frog)| Length = 532 Score = 108 bits (270), Expect = 9e-23 Identities = 82/291 (28%), Positives = 132/291 (45%), Gaps = 3/291 (1%) Frame = +1 Query: 856 KADWEIDLAKLEIRHVIAQGTYGTVYRGTYDGQ-QVAVKLLDWGEDGFATEAETTALRTS 1032 K WEI L + + QG +G V+ GT++G +VA+K L G T + Sbjct: 256 KDAWEIPRDSLRLELKLGQGCFGEVWMGTWNGTTRVAIKTLKPG----------TMSPEA 305 Query: 1033 FKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLK 1212 F QE V KL H + + A + +V EY++ G+L Sbjct: 306 FLQEAQVMKKLRHEKLVQLY-------------------AVVSEEPIYIVTEYMSKGSLL 346 Query: 1213 QYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGV 1392 +L R L +V +A ++ G++Y+ VHRD++ N+L+ K+ADFG+ Sbjct: 347 DFLKGEMGRYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGL 406 Query: 1393 AR-VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCD-MPYPDLS 1566 AR +E GA + + APE + K DV+SFGI L E+ +PYP + Sbjct: 407 ARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMV 466 Query: 1567 FADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 1719 +V V + R P CP + ++M +CW +P++RP + + +E Sbjct: 467 NREVLDQ-VERGYRMPCPPDCPESLHDLMFQCWRKDPEERPTFEYLQAFLE 516
>Q62925:M3K1_RAT Mitogen-activated protein kinase kinase kinase 1 - Rattus norvegicus| (Rat) Length = 1493 Score = 108 bits (270), Expect = 9e-23 Identities = 80/282 (28%), Positives = 134/282 (47%), Gaps = 13/282 (4%) Frame = +1 Query: 904 IAQGTYGTVYRG--TYDGQQVAVKLLDWGEDGFATEAETTALRTSFKQEVAVWHKLSHPN 1077 I G + + Y+ G +AVK + + + T +E + + ++E+ + L+HPN Sbjct: 1230 IGLGAFSSCYQAQDVGTGTLMAVKQVTYVRN---TSSEQEEVVEALREEIRMMSHLNHPN 1286 Query: 1078 VTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYLIKNRRRKLAYKV 1257 + + +GA+ ++ + +E++AG ++ L K K + V Sbjct: 1287 IIRMLGATCEKSNYNL------------------FIEWMAGASVAHLLSKYGAFKES--V 1326 Query: 1258 VVQLALDLSRGLSYLHSRKIVHRDVKTENMLLD-TQRNLKIADFGVARVEAQNPKDMTGA 1434 V+ L RGLSYLH +I+HRDVK N+L+D T + L+IADFG A A+ TGA Sbjct: 1327 VINYTEQLLRGLSYLHENQIIHRDVKGANLLIDSTGQRLRIADFGAA---ARLASKGTGA 1383 Query: 1435 -------TGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDMPYPDLSFAD---VSS 1584 GT+ +MAPEVL G+ Y R CDV+S G + E+ C P+ ++ + Sbjct: 1384 GEFQGQLLGTIAFMAPEVLRGQQYGRSCDVWSVGCAIIEMACAKPPWNAEKHSNHLALIF 1443 Query: 1585 AVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQ 1710 + P IP ++ +C + P RP E+++ Sbjct: 1444 KIASATTAPSIPSHLSPGLRDVALRCLELQPQDRPPSRELLK 1485
>Q1RMT8:IRAK4_BOVIN Interleukin-1 receptor-associated kinase 4 - Bos taurus (Bovine)| Length = 461 Score = 108 bits (270), Expect = 9e-23 Identities = 83/293 (28%), Positives = 130/293 (44%), Gaps = 16/293 (5%) Frame = +1 Query: 904 IAQGTYGTVYRGTYDGQQVAVKLLDWGEDGFATEAETTALRTSFKQEVAVWHKLSHPNVT 1083 + +G +G VY+G + + VAVK L + T L+ F QE+ V K H N+ Sbjct: 193 MGEGGFGVVYKGYVNNRTVAVKKL-----AAMVDISTEELKQQFDQEIKVMAKCQHENLV 247 Query: 1084 KFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYL-IKNRRRKLAYKVV 1260 + +G S DL C+V Y+ G+L L + L++ + Sbjct: 248 ELLGFSSDGDDL------------------CLVYVYMPNGSLLDRLSCLDGTPPLSWNMR 289 Query: 1261 VQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGVARVEAQNPKDM--TGA 1434 ++A + GLSYLH +HRD+K+ N+LLD KI+DFG+AR + + + + Sbjct: 290 CKIAQGAANGLSYLHENHHIHRDIKSANILLDEDFTAKISDFGLARASEKFAQTVMTSRI 349 Query: 1435 TGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVY----CCDMPYPDLSFADVSSAVVHQ- 1599 GT YMAPE L G+ K D+YSFG+ L E+ D D+ + + Sbjct: 350 VGTTAYMAPEALRGE-ITPKSDIYSFGVVLLEIITGLPAVDEHREPQLLLDIKEEIEDEE 408 Query: 1600 --------NLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDTS 1734 DI ++ +C +KRPD+ +V QL+E + S Sbjct: 409 KTIEDYVDRKMNDIDSTSIETMYSVASQCLHEKKNKRPDIKKVQQLLEEMTGS 461
>P15208:INSR_MOUSE Insulin receptor precursor - Mus musculus (Mouse)| Length = 1372 Score = 108 bits (270), Expect = 9e-23 Identities = 84/305 (27%), Positives = 136/305 (44%), Gaps = 19/305 (6%) Frame = +1 Query: 862 DWEIDLAKLEIRHVIAQGTYGTVYRGTYDG-------QQVAVKLLDWGEDGFATEAETTA 1020 +WE+ K+ + + QG++G VY G +VAVK ++ E+ + Sbjct: 1005 EWEVPREKITLLRELGQGSFGMVYEGNAKDIIKGEAETRVAVKTVN--------ESASLR 1056 Query: 1021 LRTSFKQEVAVWHKLSHPNVTKFVGA-SMGTTDLKIPVNDNGARANLPARACCVVVEYLA 1197 R F E +V + +V + +G S G L VV+E +A Sbjct: 1057 ERIEFLNEASVMKGFTCHHVVRLLGVVSKGQPML-------------------VVMELMA 1097 Query: 1198 GGTLKQYLIKNR--------RRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLL 1353 G LK +L R R + ++Q+ +++ G++YL+++K VHRD+ N ++ Sbjct: 1098 HGDLKSHLRSLRPDAENNPGRPPPTLQEMIQMTAEIADGMAYLNAKKFVHRDLAARNCMV 1157 Query: 1354 DTQRNLKIADFGVARVEAQNPKDMTGATGTL--GYMAPEVLDGKPYNRKCDVYSFGICLW 1527 +KI DFG+ R + G G L +M+PE L + D++SFG+ LW Sbjct: 1158 AHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTASSDMWSFGVVLW 1217 Query: 1528 EV-YCCDMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEV 1704 E+ + PY LS V V+ D P CP ++MR CW NP RP E+ Sbjct: 1218 EITSLAEQPYQGLSNEQVLKFVMDGGYL-DPPDNCPERLTDLMRMCWQFNPKMRPTFLEI 1276 Query: 1705 VQLME 1719 V L++ Sbjct: 1277 VNLLK 1281
>Q9LJM4:IKU2_ARATH Receptor-like protein kinase HAIKU2 precursor - Arabidopsis thaliana| (Mouse-ear cress) Length = 991 Score = 108 bits (270), Expect = 9e-23 Identities = 105/375 (28%), Positives = 167/375 (44%), Gaps = 37/375 (9%) Frame = +1 Query: 757 VRADKIDLTSLDIQLEQQLNKKWSKSNIKSLGPKADWEIDLAKLEIRHVIAQGTYGTVYR 936 +R DK++ T Q W S+ + L ID K E ++I +G G VY+ Sbjct: 637 IRRDKLNKTV-------QKKNDWQVSSFRLLNFNEMEIIDEIKSE--NIIGRGGQGNVYK 687 Query: 937 GTY-DGQQVAVKLLDWGEDGFATEAETTALRTS---------FKQEVAVWHKLSHPNVTK 1086 + G+ +AVK + E + +TA+ + F+ EVA + H NV K Sbjct: 688 VSLRSGETLAVKHIWCPESSHESFRSSTAMLSDGNNRSNNGEFEAEVATLSNIKHINVVK 747 Query: 1087 FVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLKQYLIKNR-RRKLAYKVVV 1263 S+ D K+ +V EY+ G+L + L + R +++ ++V Sbjct: 748 LF-CSITCEDSKL-----------------LVYEYMPNGSLWEQLHERRGEQEIGWRVRQ 789 Query: 1264 QLALDLSRGLSYLH---SRKIVHRDVKTENMLLDTQRNLKIADFGVARV----EAQNPKD 1422 LAL ++GL YLH R ++HRDVK+ N+LLD + +IADFG+A++ Q Sbjct: 790 ALALGAAKGLEYLHHGLDRPVIHRDVKSSNILLDEEWRPRIADFGLAKIIQADSVQRDFS 849 Query: 1423 MTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCCDMPYPDLSFADVSSAVV--- 1593 GTLGY+APE N K DVYSFG+ L E+ P + F + + V+ Sbjct: 850 APLVKGTLGYIAPEYAYTTKVNEKSDVYSFGVVLMELVTGKKPL-ETDFGENNDIVMWVW 908 Query: 1594 ---HQNLRPDIPRCCPSAFAN-----------IMRKCWDGNPDKRPDMDEVVQLMEALDT 1731 + R + + ++ + I C D +P RP M VV ++E ++ Sbjct: 909 SVSKETNREMMMKLIDTSIEDEYKEDALKVLTIALLCTDKSPQARPFMKSVVSMLEKIEP 968 Query: 1732 S--KGGGMIPDGQSS 1770 S K G G+S+ Sbjct: 969 SYNKNSGEASYGESA 983
>P18461:FGFR2_CHICK Fibroblast growth factor receptor 2 precursor - Gallus gallus| (Chicken) Length = 823 Score = 108 bits (270), Expect = 9e-23 Identities = 85/315 (26%), Positives = 139/315 (44%), Gaps = 26/315 (8%) Frame = +1 Query: 865 WEIDLAKLEIRHVIAQGTYGTVYRGTYDGQQ---------VAVKLLDWGEDGFATEAETT 1017 WE KL + + +G +G V G VAVK+L +D ATE + + Sbjct: 476 WEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDRPKEAVTVAVKMLK--DD--ATEKDLS 531 Query: 1018 ALRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLA 1197 L + + + H N+ +GA L V+VEY + Sbjct: 532 DLVSEMEMMKMIG---KHKNIINLLGACTQDGPLY------------------VIVEYAS 570 Query: 1198 GGTLKQYLIKNR--------------RRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVK 1335 G L++YL R ++ +K +V L+RG+ YL S+K +HRD+ Sbjct: 571 KGNLREYLRARRPPGMEYSFDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLA 630 Query: 1336 TENMLLDTQRNLKIADFGVAR--VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYS 1509 N+L+ +KIADFG+AR K T + +MAPE L + Y + DV+S Sbjct: 631 ARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWS 690 Query: 1510 FGICLWEVYCC-DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKR 1686 FG+ +WE++ PYP + ++ ++ + R D P C + +MR CW P +R Sbjct: 691 FGVLMWEIFTLGGSPYPGIPVEELFK-LLKEGHRMDKPANCTNELYMMMRDCWQAVPSQR 749 Query: 1687 PDMDEVVQLMEALDT 1731 P ++V+ ++ + T Sbjct: 750 PTFKQLVEDLDRILT 764
>Q04589:FGFR1_RAT Basic fibroblast growth factor receptor 1 precursor - Rattus| norvegicus (Rat) Length = 822 Score = 108 bits (270), Expect = 9e-23 Identities = 96/344 (27%), Positives = 148/344 (43%), Gaps = 40/344 (11%) Frame = +1 Query: 865 WEIDLAKLEIRHVIAQGTYGTVYRGTYDG---------QQVAVKLLDWGEDGFATEAETT 1017 WE+ +L + + +G +G V G +VAVK+L ATE + + Sbjct: 471 WELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLK----SDATEKDLS 526 Query: 1018 ALRTSFKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLA 1197 L + + + H N+ +GA L V+VEY + Sbjct: 527 DLISEMEMMKMIG---KHKNIINLLGACTQDGPLY------------------VIVEYAS 565 Query: 1198 GGTLKQYLIKNRRRKLAY--------------KVVVQLALDLSRGLSYLHSRKIVHRDVK 1335 G L++YL R L Y K +V A ++RG+ YL S+K +HRD+ Sbjct: 566 KGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLA 625 Query: 1336 TENMLLDTQRNLKIADFGVAR--VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYS 1509 N+L+ +KIADFG+AR K T + +MAPE L + Y + DV+S Sbjct: 626 ARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWS 685 Query: 1510 FGICLWEVYCC-DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKR 1686 FG+ LWE++ P P + ++ ++ + R D P C + +MR CW+ P +R Sbjct: 686 FGVLLWEIFTLGGSPNPGVPVEELFK-LLKEGHRMDKPSNCTNELYMMMRDCWNAVPSQR 744 Query: 1687 P-------DMDEVVQL---MEALDTS----KGGGMIPDGQSSGC 1776 P D+D +V L E LD S + PD +SS C Sbjct: 745 PTFKQLVEDLDRIVALTSNQEYLDLSMPLDQDSPSFPDTRSSTC 788
>Q07498:EPHB3_CHICK Ephrin type-B receptor 3 - Gallus gallus (Chicken)| Length = 988 Score = 108 bits (270), Expect = 9e-23 Identities = 84/298 (28%), Positives = 138/298 (46%), Gaps = 12/298 (4%) Frame = +1 Query: 868 EIDLAKLEIRHVIAQGTYGTVYRGTYD--GQQ---VAVKLLDWGEDGFATEAETTALRTS 1032 EID++ ++I VI G +G V RG G++ VA+K L G T R Sbjct: 617 EIDISCVKIEEVIGAGEFGEVCRGRLKLPGRREIFVAIKTLKVGY--------TERQRRD 668 Query: 1033 FKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLK 1212 F E ++ + HPN+ G +R ++ E++ L Sbjct: 669 FLSEASIMGQFDHPNIIHLEGVVT------------------KSRPVMIITEFMENCALD 710 Query: 1213 QYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGV 1392 +L N + ++V L ++ G+ YL VHRD+ N+L+++ K++DFG+ Sbjct: 711 SFLRLNDGQFTVIQLVGMLR-GIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGL 769 Query: 1393 ARVEAQNPKDMTGATGTLG------YMAPEVLDGKPYNRKCDVYSFGICLWEVYCC-DMP 1551 +R +P D T T +LG + APE + + + DV+S+GI +WEV + P Sbjct: 770 SRFLEDDPADPT-YTSSLGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERP 828 Query: 1552 YPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 1725 Y D+S DV +A V Q+ R P CP+A +M CW + + RP ++V ++ L Sbjct: 829 YWDMSNQDVINA-VEQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFAQIVNTLDKL 885
>O08680:EPHA3_RAT Ephrin type-A receptor 3 precursor - Rattus norvegicus (Rat)| Length = 984 Score = 108 bits (270), Expect = 9e-23 Identities = 78/300 (26%), Positives = 136/300 (45%), Gaps = 9/300 (3%) Frame = +1 Query: 868 EIDLAKLEIRHVIAQGTYGTVYRG-----TYDGQQVAVKLLDWGEDGFATEAETTALRTS 1032 E+D + I V+ G +G V G + VA+K L G T R Sbjct: 616 ELDATNIAIDKVVGAGEFGEVCSGRLKLPSKKEISVAIKTLKVGY--------TEKQRRD 667 Query: 1033 FKQEVAVWHKLSHPNVTKFVGASMGTTDLKIPVNDNGARANLPARACCVVVEYLAGGTLK 1212 F E ++ + HPN+ + G ++ +V EY+ G+L Sbjct: 668 FLGEASIMGQFDHPNIIRLEGVVT------------------KSKPVMIVTEYMENGSLD 709 Query: 1213 QYLIKNRRRKLAYKVVVQLALDLSRGLSYLHSRKIVHRDVKTENMLLDTQRNLKIADFGV 1392 +L K+ + ++V L ++ G+ YL VHRD+ N+L+++ K++DFG+ Sbjct: 710 SFLRKHDAQFTVIQLVGMLR-GIASGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGL 768 Query: 1393 ARVEAQNPK---DMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEVYCC-DMPYPD 1560 +RV +P+ G + + +PE + + DV+S+GI LWEV + PY + Sbjct: 769 SRVLEDDPEAAYTTRGGKIPVRWTSPEATAYRKFTSASDVWSYGIVLWEVMSYGERPYWE 828 Query: 1561 LSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDTSKG 1740 +S DV A V + R +P CP+A +M CW + + RP +++V +++ L + G Sbjct: 829 MSNQDVIKA-VDEGYRLPLPMDCPAALYQLMLDCWQKDRNNRPKFEQIVSILDKLIRNPG 887 Database: uniprot_sprot.fasta.out Posted date: Jul 19, 2007 5:58 PM Number of letters in database: 100,686,439 Number of sequences in database: 274,295 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 274295 Number of Hits to DB: 380,028,369 Number of extensions: 8654243 Number of successful extensions: 35403 Number of sequences better than 10.0: 2630 Number of HSP's gapped: 31883 Number of HSP's successfully gapped: 2747 Length of query: 724 Length of database: 100,686,439 Length adjustment: 121 Effective length of query: 603 Effective length of database: 67,496,744 Effective search space: 40700536632 Effective search space used: 40700536632 Neighboring words threshold: 12 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
