>P38605:CAS1_ARATH Cycloartenol synthase - Arabidopsis thaliana (Mouse-ear cress)|
          Length = 759
 Score =  607 bits (1566), Expect = e-173
 Identities = 267/490 (54%), Positives = 365/490 (74%), Gaps = 1/490 (0%)
 Frame = +1

Query: 82   MWRLKVSEGGSPWLRSPSSFLGRAVWEFDPELGTPEERAEVERLRRDYTRCRFEKRESQD 261
            MW+LK++EGGSPWLR+ ++ +GR  WEFDP LGTPE+ A VE  R+ ++  RF ++ S D
Sbjct: 1    MWKLKIAEGGSPWLRTTNNHVGRQFWEFDPNLGTPEDLAAVEEARKSFSDNRFVQKHSAD 60

Query: 262  LLMRMQYAKLNPLPAIVPKVHLDDNAEVTEEIISASLRQALNQYCTLQAHDGHWPGDNSG 441
            LLMR+Q+++ N +  ++P+V ++D  +VTEE++  +L++ L+ Y T+QAHDGHWPGD  G
Sbjct: 61   LLMRLQFSRENLISPVLPQVKIEDTDDVTEEMVETTLKRGLDFYSTIQAHDGHWPGDYGG 120

Query: 442  IMFLMPMFIFSLYVTENLHSVISSDHQREICRHIYNHQNEDGGWGTHVIGPSNMLCSCLN 621
             MFL+P  I +L +T  L++V+S  H++E+ R++YNHQNEDGGWG H+ GPS M  S LN
Sbjct: 121  PMFLLPGLIITLSITGALNTVLSEQHKQEMRRYLYNHQNEDGGWGLHIEGPSTMFGSVLN 180

Query: 622  YAALRLLGEMLDCDNGALAKGRAWILSHGSATAVPQWGKIFLSIIGAYDWVGNNPIFPEL 801
            Y  LRLLGE  +  +G + KGR WIL+HG AT +  WGK++LS++GA++W GNNP+ PE+
Sbjct: 181  YVTLRLLGEGPNDGDGDMEKGRDWILNHGGATNITSWGKMWLSVLGAFEWSGNNPLPPEI 240

Query: 802  WMVPYFLPIHPGRFWCFCRMVYMSMAYLYGKKFVGPITPTILALREELYNIPYRNIDWNK 981
            W++PYFLPIHPGR WC CRMVY+ M+YLYGK+FVGPIT T+L+LR+EL+ +PY  ++WN+
Sbjct: 241  WLLPYFLPIHPGRMWCHCRMVYLPMSYLYGKRFVGPITSTVLSLRKELFTVPYHEVNWNE 300

Query: 982  ARQSCAKEDCRCPHSKVQRTIFYCFHKFVEPVISSWPTNKLRERALSKLMEHIHYNDETT 1161
            AR  CAKED   PH  VQ  ++   HK VEPV+  WP   LRE+A+   +EHIHY DE T
Sbjct: 301  ARNLCAKEDLYYPHPLVQDILWASLHKIVEPVLMRWPGANLREKAIRTAIEHIHYEDENT 360

Query: 1162 EYITICPVDKALSMICCWVENPNSYALKQHLPRVYDYMWLAEDGMKAKIADGCQSWEISF 1341
             YI I PV+K L+M+CCWVE+PNS A K HLPR++D++WLAEDGMK +  +G Q W+  F
Sbjct: 361  RYICIGPVNKVLNMLCCWVEDPNSEAFKLHLPRIHDFLWLAEDGMKMQGYNGSQLWDTGF 420

Query: 1342 IIQAFVSTDLIGEFSKTIEKAHDFLKNSQVISNCP-SYQKNYRHRSKGSWTLSTIDIGWG 1518
             IQA ++T+L+ E+   +EKAH F+KNSQV+ +CP      YRH SKG+W  ST D GW 
Sbjct: 421  AIQAILATNLVEEYGPVLEKAHSFVKNSQVLEDCPGDLNYWYRHISKGAWPFSTADHGWP 480

Query: 1519 VSDCTAEAIK 1548
            +SDCTAE +K
Sbjct: 481  ISDCTAEGLK 490



 Score =  189 bits (480), Expect(2) = 2e-60
 Identities = 88/161 (54%), Positives = 120/161 (74%), Gaps = 2/161 (1%)
 Frame = +2

Query: 1571 HERRRTNSWLEDLNPSDSFQNIVIDHPSMECTSSVLEGLILFKEQYPHYRCKEIEKCIKN 1750
            +E  R+  WLE +NP+++F +IVID+P +ECTS+ ++ LI F++ YP +R KE+++CI+ 
Sbjct: 532  YELTRSYPWLELINPAETFGDIVIDYPYVECTSAAIQALISFRKLYPGHRKKEVDECIEK 591

Query: 1751 AATYIENKQRKNGSWYGTWGICFTYGAFFAVKGLAASGRTYDNSDCMRKSCEFLLSKQQS 1930
            A  +IE+ Q  +GSWYG+W +CFTYG +F VKGL A G+T  NS  + K+CEFLLSKQQ 
Sbjct: 592  AVKFIESIQAADGSWYGSWAVCFTYGTWFGVKGLVAVGKTLKNSPHVAKACEFLLSKQQP 651

Query: 1931 TGGWGESYLSIETEEY--VDSGSSHAVATAWAMLALIYAGQ 2047
            +GGWGESYLS + + Y  +D   SH V TAWAMLALI AGQ
Sbjct: 652  SGGWGESYLSCQDKVYSNLDGNRSHVVNTAWAMLALIGAGQ 692



 Score = 66.6 bits (161), Expect(2) = 2e-60
 Identities = 31/59 (52%), Positives = 42/59 (71%)
 Frame = +1

Query: 2050 PLYRAAKLLMNMQLDSGEFPQQEHMGCANSAFFFNYPNYRNIFPIMALGEFRRRLIENQ 2226
            PL+RAA+ L+N Q+++G+FPQQE MG  N      Y  YRNIFPI ALGE+R +++  Q
Sbjct: 699  PLHRAARYLINAQMENGDFPQQEIMGVFNRNCMITYAAYRNIFPIWALGEYRCQVLLQQ 757

>Q8BLN5:ERG7_MOUSE Lanosterol synthase - Mus musculus (Mouse)|
          Length = 733

 Score =  304 bits (779), Expect(3) = e-125
 Identities = 149/389 (38%), Positives = 229/389 (58%), Gaps = 3/389 (0%)
 Frame = +1

Query: 391  YCTLQAHDGHWPGDNSGIMFLMPMFIFSLYVTENLHSVISSDHQREICRHIYNHQNEDGG 570
            Y  LQA DGHW GD  G +FL+P  + + +++   H  + + ++ E+ R++ + Q  DGG
Sbjct: 85   YAKLQAEDGHWAGDYGGPLFLLPGLLITCHIS---HISLPAGYREEMVRYLRSVQLPDGG 141

Query: 571  WGTHVIGPSNMLCSCLNYAALRLLGEMLDCDNGALAKGRAWILSHGSATAVPQWGKIFLS 750
            WG H+   S +  + LNY ALR+LG  +  D+  L + R  +   G A A+P WGK +L+
Sbjct: 142  WGLHIEDKSTVFGTALNYVALRILG--IGPDDPDLVRARNVLHKKGGAVAIPSWGKFWLA 199

Query: 751  IIGAYDWVGNNPIFPELWMVPYFLPIHPGRFWCFCRMVYMSMAYLYGKKFVGPITPTILA 930
            ++  Y W G N +FPE+W+ P ++P HP   WC CR VY+ M+Y Y  +      P + +
Sbjct: 200  VLNVYSWEGLNTLFPEMWLFPEWVPAHPSTLWCHCRQVYLPMSYCYATRLSASEDPLVQS 259

Query: 931  LREELYNIPYRNIDWNKARQSCAKEDCRCPHSKVQRTIFYCFHKFVEPVISSWPTNKLRE 1110
            LR+ELY   Y +IDW   R + + ++   PHS +   ++   + +       + +  LR+
Sbjct: 260  LRQELYVQDYASIDWPAQRNNVSPDEMYTPHSWLLHVVYGLLNLY-----ERFHSTSLRK 314

Query: 1111 RALSKLMEHIHYNDETTEYITICPVDKALSMICCW-VENPNSYALKQHLPRVYDYMWLAE 1287
             A+  L EHI  +D  T+ I+I P+ K ++M+  W V+ P+S A ++H+ R+ DY+WL  
Sbjct: 315  WAVQMLYEHIAADDCFTKCISIGPISKTINMLVRWSVDGPSSPAFQEHVSRIKDYLWLGL 374

Query: 1288 DGMKAKIADGCQSWEISFIIQAFVSTDL--IGEFSKTIEKAHDFLKNSQVISNCPSYQKN 1461
            DGMK +  +G Q W+ SF IQA +        EF   ++KAH+FL+ SQV  NCP YQK 
Sbjct: 375  DGMKMQGTNGSQIWDTSFAIQALLEAGAHHRPEFLPCLQKAHEFLRLSQVPENCPDYQKY 434

Query: 1462 YRHRSKGSWTLSTIDIGWGVSDCTAEAIK 1548
            YRH  KG ++ ST+D GW V+DCTAE +K
Sbjct: 435  YRHMRKGGFSFSTLDCGWIVADCTAEGLK 463



 Score =  143 bits (360), Expect(3) = e-125
 Identities = 66/158 (41%), Positives = 99/158 (62%), Gaps = 3/158 (1%)
 Frame = +2

Query: 1571 HERRRTNSWLEDLNPSDSFQNIVIDHPSMECTSSVLEGLILFKEQYPHYRCKEIEKCIKN 1750
            +E++R    LE LNPS+ F +I+ID+  +ECTS+V++ L  F E +P YR  E+ + +  
Sbjct: 504  YEKKRGGYLLELLNPSEVFGDIMIDYTYVECTSAVMQALKHFHEHFPDYRAAEVRETLNQ 563

Query: 1751 AATYIENKQRKNGSWYGTWGICFTYGAFFAVKGLAASGRTY-DNSDC--MRKSCEFLLSK 1921
               +   KQR +GSW G+WG+CFTYG +F ++  A  G TY D + C  + ++C FLLS+
Sbjct: 564  GLDFCRRKQRADGSWEGSWGVCFTYGTWFGLEAFACMGHTYQDGAACAEVAQACNFLLSQ 623

Query: 1922 QQSTGGWGESYLSIETEEYVDSGSSHAVATAWAMLALI 2035
            Q + GGWGE + S E   YV S  S   +T WA++ L+
Sbjct: 624  QMADGGWGEDFESCEQRRYVQSARSQVHSTCWALMGLM 661



 Score = 47.4 bits (111), Expect(3) = e-125
 Identities = 22/55 (40%), Positives = 32/55 (58%)
 Frame = +1

Query: 2059 RAAKLLMNMQLDSGEFPQQEHMGCANSAFFFNYPNYRNIFPIMALGEFRRRLIEN 2223
            R  + L+  QL +G++PQ+   G  N +   +Y +YRNIFPI ALG F     +N
Sbjct: 673  RGIRCLLGKQLPNGDWPQENISGVFNKSCAISYTSYRNIFPIWALGRFSNLYPDN 727

>P48450:ERG7_RAT Lanosterol synthase - Rattus norvegicus (Rat)|
          Length = 733

 Score =  299 bits (765), Expect(3) = e-123
 Identities = 145/389 (37%), Positives = 227/389 (58%), Gaps = 3/389 (0%)
 Frame = +1

Query: 391  YCTLQAHDGHWPGDNSGIMFLMPMFIFSLYVTENLHSVISSDHQREICRHIYNHQNEDGG 570
            Y  LQA DGHW GD  G +FL+P  + + ++    H  + + ++ E+ R++ + Q  DGG
Sbjct: 85   YAKLQAEDGHWAGDYGGPLFLLPGLLITCHIA---HIPLPAGYREEMVRYLRSVQLPDGG 141

Query: 571  WGTHVIGPSNMLCSCLNYAALRLLGEMLDCDNGALAKGRAWILSHGSATAVPQWGKIFLS 750
            WG H+   S +  + L+Y +LR+LG  +  D+  L + R  +   G A A+P WGK +L+
Sbjct: 142  WGLHIEDKSTVFGTALSYVSLRILG--IGPDDPDLVRARNILHKKGGAVAIPSWGKFWLA 199

Query: 751  IIGAYDWVGNNPIFPELWMVPYFLPIHPGRFWCFCRMVYMSMAYLYGKKFVGPITPTILA 930
            ++  Y W G N +FPE+W++P + P HP   WC CR VY+ M+Y Y  +      P + +
Sbjct: 200  VLNVYSWEGINTLFPEMWLLPEWFPAHPSTLWCHCRQVYLPMSYCYATRLSASEDPLVQS 259

Query: 931  LREELYNIPYRNIDWNKARQSCAKEDCRCPHSKVQRTIFYCFHKFVEPVISSWPTNKLRE 1110
            LR+ELY   Y +IDW   + +   +D   PHS +   ++   + +       + +  LR+
Sbjct: 260  LRQELYVEDYASIDWPAQKNNVCPDDMYTPHSWLLHVVYGLLNLY-----ERFHSTSLRK 314

Query: 1111 RALSKLMEHIHYNDETTEYITICPVDKALSMICCW-VENPNSYALKQHLPRVYDYMWLAE 1287
             A+  L EH+  +D  T+ I+I P+ K ++M+  W V+ P+S A ++H+ R+ DY+WL  
Sbjct: 315  WAIQLLYEHVAADDRFTKCISIGPISKTVNMLIRWSVDGPSSPAFQEHVSRIKDYLWLGL 374

Query: 1288 DGMKAKIADGCQSWEISFIIQAFVSTDL--IGEFSKTIEKAHDFLKNSQVISNCPSYQKN 1461
            DGMK +  +G Q+W+ SF +QA +        EF   ++KAH+FL+ SQV  N P YQK 
Sbjct: 375  DGMKMQGTNGSQTWDTSFAVQALLEAGAHRRPEFLPCLQKAHEFLRLSQVPDNNPDYQKY 434

Query: 1462 YRHRSKGSWTLSTIDIGWGVSDCTAEAIK 1548
            YRH  KG +  ST+D GW V+DCTAEA+K
Sbjct: 435  YRHMHKGGFPFSTLDCGWIVADCTAEALK 463



 Score =  138 bits (348), Expect(3) = e-123
 Identities = 64/158 (40%), Positives = 95/158 (60%), Gaps = 3/158 (1%)
 Frame = +2

Query: 1571 HERRRTNSWLEDLNPSDSFQNIVIDHPSMECTSSVLEGLILFKEQYPHYRCKEIEKCIKN 1750
            +E +R    LE LNPS+ F +I+ID+  +ECTS+V++ L  F+E +P +R  E  + +  
Sbjct: 504  YETKRGGYLLELLNPSEVFGDIMIDYTYVECTSAVMQALRHFREYFPDHRATESRETLNQ 563

Query: 1751 AATYIENKQRKNGSWYGTWGICFTYGAFFAVKGLAASGRTYDNSDC---MRKSCEFLLSK 1921
               +   KQR +GSW G+WG+CFTYG +F ++  A  G  Y N      + ++C FLLS+
Sbjct: 564  GLDFCRKKQRADGSWEGSWGVCFTYGTWFGLEAFACMGHIYQNRTACAEVAQACHFLLSR 623

Query: 1922 QQSTGGWGESYLSIETEEYVDSGSSHAVATAWAMLALI 2035
            Q + GGWGE + S E   YV S  S   +T WA+L L+
Sbjct: 624  QMADGGWGEDFESCEQRRYVQSAGSQVHSTCWALLGLM 661



 Score = 48.9 bits (115), Expect(3) = e-123
 Identities = 22/48 (45%), Positives = 30/48 (62%)
 Frame = +1

Query: 2059 RAAKLLMNMQLDSGEFPQQEHMGCANSAFFFNYPNYRNIFPIMALGEF 2202
            R  + L+  QL +G++PQ+   G  N +   +Y NYRNIFPI ALG F
Sbjct: 673  RGIRCLLGKQLPNGDWPQENISGVFNKSCAISYTNYRNIFPIWALGRF 720

>P84466:ERG7_BOVIN Lanosterol synthase - Bos taurus (Bovine)|
          Length = 732

 Score =  297 bits (761), Expect(3) = e-123
 Identities = 154/399 (38%), Positives = 227/399 (56%), Gaps = 6/399 (1%)
 Frame = +1

Query: 373  RQALNQ---YCTLQAHDGHWPGDNSGIMFLMPMFIFSLYVTENLHSVISSDHQREICRHI 543
            R ALN    Y  LQ  DGHW GD  G +FL+P  + + +V    +  + + ++ EI R++
Sbjct: 75   RGALNGVTFYAALQTEDGHWAGDYGGPLFLLPGLLITCHVA---NIPLPAGYREEIIRYL 131

Query: 544  YNHQNEDGGWGTHVIGPSNMLCSCLNYAALRLLGEMLDCDNGALAKGRAWILSHGSATAV 723
             + Q  DGGWG H+   S +  + LNY +LR+LG  +  D+  L + R  +   G A  +
Sbjct: 132  RSVQLPDGGWGLHIEDKSTVFGTALNYVSLRILG--VGPDDPDLVRARNLLHKKGGAVFI 189

Query: 724  PQWGKIFLSIIGAYDWVGNNPIFPELWMVPYFLPIHPGRFWCFCRMVYMSMAYLYGKKFV 903
            P WGK +L+++  Y W G N +FPE+W+ P ++P HP   WC CR VY+ MAY Y  +  
Sbjct: 190  PSWGKFWLAVLNVYSWEGLNTLFPEMWLFPDWMPAHPSTIWCHCRQVYLPMAYCYSTRLS 249

Query: 904  GPITPTILALREELYNIPYRNIDWNKARQSCAKEDCRCPHSKVQRTIFYCFHKFVEPVIS 1083
                P + +LR+ELY   Y  IDW   R S A +D   PHS +   ++   + +      
Sbjct: 250  AEEGPLVQSLRQELYLEDYSCIDWAAHRNSVAPDDLYTPHSWLLHVVYAILNLY-----E 304

Query: 1084 SWPTNKLRERALSKLMEHIHYNDETTEYITICPVDKALSMICCW-VENPNSYALKQHLPR 1260
               +  LR+ A  KL EHI  +D  T+ I+I P+ K ++M+  W V+ P S   ++H+ R
Sbjct: 305  RHHSTSLRQWATQKLYEHIAADDRFTKCISIGPISKTINMLVRWHVDGPASAVFQEHVSR 364

Query: 1261 VYDYMWLAEDGMKAKIADGCQSWEISFIIQAFVS--TDLIGEFSKTIEKAHDFLKNSQVI 1434
            + DY+WL  DGMK +  +G Q W+ +F IQA +        EF   + KAH++L+ SQV 
Sbjct: 365  IPDYLWLGLDGMKMQGTNGSQIWDTAFAIQALLEARAQHRPEFWSCLRKAHEYLRISQVP 424

Query: 1435 SNCPSYQKNYRHRSKGSWTLSTIDIGWGVSDCTAEAIKN 1551
             N P YQK YRH SKG ++ ST+D GW V+DCTAEA+K+
Sbjct: 425  DNFPDYQKYYRHMSKGGFSFSTLDCGWIVADCTAEALKS 463



 Score =  142 bits (357), Expect(3) = e-123
 Identities = 65/158 (41%), Positives = 99/158 (62%), Gaps = 3/158 (1%)
 Frame = +2

Query: 1571 HERRRTNSWLEDLNPSDSFQNIVIDHPSMECTSSVLEGLILFKEQYPHYRCKEIEKCIKN 1750
            +E +R    LE LNPS+ F +I+ID+  +ECTS+V++ L  F +Q+P +R  EI + ++ 
Sbjct: 503  YETKRGGHLLELLNPSEVFGDIMIDYTYVECTSAVMQALKTFHKQFPDHRAGEIRETLEQ 562

Query: 1751 AATYIENKQRKNGSWYGTWGICFTYGAFFAVKGLAASGRTYDNSDC---MRKSCEFLLSK 1921
               +   KQR +GSW G+WG+CFTYGA+F ++  A  G TY N      + ++C+FLLS+
Sbjct: 563  GLQFCRQKQRPDGSWEGSWGVCFTYGAWFGLEAFACMGHTYHNGVACAEISRACDFLLSR 622

Query: 1922 QQSTGGWGESYLSIETEEYVDSGSSHAVATAWAMLALI 2035
            Q + GGWGE + S +   YV S  S    T WA++ L+
Sbjct: 623  QMADGGWGEDFESCKQRRYVQSAQSQIHNTCWALMGLM 660



 Score = 47.0 bits (110), Expect(3) = e-123
 Identities = 21/52 (40%), Positives = 30/52 (57%)
 Frame = +1

Query: 2053 LYRAAKLLMNMQLDSGEFPQQEHMGCANSAFFFNYPNYRNIFPIMALGEFRR 2208
            L R    L+  QL +G++PQ+   G  N +   +Y +YRN+FPI  LG F R
Sbjct: 670  LERGVSYLLEKQLPNGDWPQENISGVFNKSCAISYTSYRNVFPIWTLGRFSR 721

>Q96WJ0:ERG7_PNECA Lanosterol synthase - Pneumocystis carinii|
          Length = 719

 Score =  301 bits (770), Expect(3) = e-121
 Identities = 169/452 (37%), Positives = 246/452 (54%), Gaps = 5/452 (1%)
 Frame = +1

Query: 208  RLRRDYTRCRFEKRESQDLLMRMQYAKLNPLPAIVPKVHLDDNAEVTEEIISASLRQALN 387
            R R  Y +   E+RE     M   +   N        + L +       I SA  R+  +
Sbjct: 27   RQRWKYLKTEEERRERPQTYMEKYFLGKN--------MDLPEQPAAKTPIESA--RKGFS 76

Query: 388  QYCTLQAHDGHWPGDNSGIMFLMPMFIFSLYVTENLHSVISSDHQR-EICRHIYNHQN-E 561
             Y  LQ  DG+W  +  G+MFL+P  I ++Y+++    +   D  R E+ R++ NH N E
Sbjct: 77   FYKHLQTSDGNWACEYGGVMFLLPGLIIAMYISK----IEFPDEMRIEVIRYLVNHANPE 132

Query: 562  DGGWGTHVIGPSNMLCSCLNYAALRLLGEMLDCDNGALAKGRAWILSHGSATAVPQWGKI 741
            DGGWG H+ G S +  + LNY  LR+LG  L  D+    K R  +   G A   PQWGK 
Sbjct: 133  DGGWGIHIEGKSTVFGTALNYVVLRILG--LGPDHPVTMKARIRLNELGGAIGCPQWGKF 190

Query: 742  FLSIIGAYDWVGNNPIFPELWMVPYFLPIHPGRFWCFCRMVYMSMAYLYGKKFVGPITPT 921
            +L+++  Y W G NPI PE WM+P +LPIHP R+W   R VY+ M Y+YG+KF  P+ P 
Sbjct: 191  WLAVLNCYGWEGINPILPEFWMLPEWLPIHPSRWWVHTRAVYLPMGYIYGEKFTAPVDPL 250

Query: 922  ILALREELYNIPYRNIDWNKARQSCAKEDCRCPHSKVQRTIFYCFHKFVEPVISSWPTNK 1101
            I +LREELY  PY +I+++K R + +  D   PH++  R I      +      SW    
Sbjct: 251  IESLREELYTQPYSSINFSKHRNTTSPVDVYVPHTRFLRVINSILTFYHTIFRFSW---- 306

Query: 1102 LRERALSKLMEHIHYNDETTEYITICPVDKALSMICC-WVENPNSYALKQHLPRVYDYMW 1278
            +++ A     + I Y ++ T+++ I PV+ ++ ++   W E P+SYA K H  R+ D++W
Sbjct: 307  IKDMASKYAYKLIEYENKNTDFLCIGPVNFSIHILAVYWKEGPDSYAFKSHKERMADFLW 366

Query: 1279 LAEDGMKAKIADGCQSWEISFIIQAFVSTDLI--GEFSKTIEKAHDFLKNSQVISNCPSY 1452
            +++ GM     +G Q W+ SF +QA V + L    EF   + KA DFL   Q+  NC   
Sbjct: 367  ISKKGMMMNGTNGVQLWDTSFAVQALVESGLAEDPEFKDHMIKALDFLDKCQIQKNCDDQ 426

Query: 1453 QKNYRHRSKGSWTLSTIDIGWGVSDCTAEAIK 1548
            QK YRHR KG+W  ST   G+ VSDCTAEA+K
Sbjct: 427  QKCYRHRRKGAWPFSTRQQGYTVSDCTAEALK 458



 Score =  136 bits (343), Expect(3) = e-121
 Identities = 66/158 (41%), Positives = 95/158 (60%), Gaps = 1/158 (0%)
 Frame = +2

Query: 1571 HERRRTNSWLEDLNPSDSFQNIVIDHPSMECTSSVLEGLILFKEQYPHYRCKEIEKCIKN 1750
            +E  R  SWLE +NP++ F +I+I+H   ECT++ +  L  F+    HYR  EI K +KN
Sbjct: 498  YELIRGPSWLEFINPAEVFGDIMIEHSYPECTTAAVTALCYFRSLCSHYRGPEINKSVKN 557

Query: 1751 AATYIENKQRKNGSWYGTWGICFTYGAFFAVKGLAASGRTYDNSDCMRKSCEFLLSKQQS 1930
            A  +I+  QR +GSWY +W ICFTY   FA++ L+     Y+NS   R++C+FL++KQ+ 
Sbjct: 558  AIQFIKESQRPDGSWYESWAICFTYATMFALESLSCVKDFYENSFHSRRACDFLVNKQEE 617

Query: 1931 TGGWGESYLSIETEEYV-DSGSSHAVATAWAMLALIYA 2041
             GGW E Y S     +      S  V TAWA + L+YA
Sbjct: 618  DGGWSEGYQSCTDGIWTRHPTGSQVVQTAWACIGLMYA 655



 Score = 42.7 bits (99), Expect(3) = e-121
 Identities = 24/68 (35%), Positives = 35/68 (51%), Gaps = 5/68 (7%)
 Frame = +1

Query: 2023 ACIDLCWP-----VPLYRAAKLLMNMQLDSGEFPQQEHMGCANSAFFFNYPNYRNIFPIM 2187
            ACI L +       P+ R   L+M+ Q  +GE+ Q+   G  N     +YPNY+  F I 
Sbjct: 648  ACIGLMYANYPDETPIKRGINLIMSRQQPNGEWKQEAIEGVFNKNCMISYPNYKFNFTIK 707

Query: 2188 ALGEFRRR 2211
            ALG + +R
Sbjct: 708  ALGMYSKR 715



 Score = 32.3 bits (72), Expect = 9.4
 Identities = 22/73 (30%), Positives = 32/73 (43%), Gaps = 1/73 (1%)
 Frame = +1

Query: 358 ISASLRQALNQYCTLQAHDGHWPGDNSGIMFLMPMFIF-SLYVTENLHSVISSDHQREIC 534
           I+ S++ A+      Q  DG W    +       MF   SL   ++ +   +S H R  C
Sbjct: 551 INKSVKNAIQFIKESQRPDGSWYESWAICFTYATMFALESLSCVKDFYE--NSFHSRRAC 608

Query: 535 RHIYNHQNEDGGW 573
             + N Q EDGGW
Sbjct: 609 DFLVNKQEEDGGW 621

>Q10231:ERG7_SCHPO Lanosterol synthase - Schizosaccharomyces pombe (Fission yeast)|
          Length = 721

 Score =  254 bits (650), Expect(3) = e-112
 Identities = 134/386 (34%), Positives = 214/386 (55%), Gaps = 3/386 (0%)
 Frame = +1

Query: 400  LQAHDGHWPGDNSGIMFLMPMFIFSLYVTENLHSVISSDHQREICRHIYNHQNEDGGWGT 579
            LQ  DGHW     G MFL+   +F+ Y+++   +        EI +++ NH N+DGGWG 
Sbjct: 84   LQLPDGHWASPYEGPMFLICGAVFAFYISQ---TPFPKGWAPEIIQYLINHTNDDGGWGI 140

Query: 580  HVIGPSNMLCSCLNYAALRLLGEMLDCDNGALAKGRAWILSHGSATAVPQWGKIFLSIIG 759
            H  G S +  + +NY  LR+LG  +D  +    + R  +   G A   P WGK +L+ + 
Sbjct: 141  HTEGVSTVFGTSMNYVVLRILG--MDAGHPVATRARNRLHELGGAIGCPHWGKFWLATLN 198

Query: 760  AYDWVGNNPIFPELWMVPYFLPIHPGRFWCFCRMVYMSMAYLYGKKFVGPITPTILALRE 939
             YDW G NPI PELW++P ++P HPG++WC  R+VY+ M Y+YG++   P    I+ LR+
Sbjct: 199  CYDWDGVNPIPPELWLLPDWIPFHPGKWWCHVRLVYLPMGYMYGERLKCPKDSLIMQLRK 258

Query: 940  ELYNIPYRNIDWNKARQSCAKEDCRCPHSKVQRTIFYCFHKFVEPVISSWPTNKLRERAL 1119
            ELY   Y +I++   R + +  D   PH+++   + +   K+   +  SW    L++   
Sbjct: 259  ELYVENYDSINFADHRNTISDVDLYFPHTQILDRLNWILEKYFTYLRPSW----LKKLGT 314

Query: 1120 SKLMEHIHYNDETTEYITICPVDKALSMICCWV-ENPNSYALKQHLPRVYDYMWLAEDGM 1296
             +  E I   D+ T+Y  I PV+ A++ +C +  E P+S A ++H+ R++D+MW+  +GM
Sbjct: 315  RRAYELIKIEDQNTDYSCIGPVNAAMNTVCVYFHEGPSSKAFQKHIQRLHDFMWVQPEGM 374

Query: 1297 KAKIADGCQSWEISFIIQAFVSTDLIGE--FSKTIEKAHDFLKNSQVISNCPSYQKNYRH 1470
              +  +G Q WE SF +QA V + L  +  F   I KA +FL   Q+ +        YR+
Sbjct: 375  LMRGTNGLQVWETSFTLQALVESGLYEKEAFKPDIAKALEFLDRQQIRTQYEG--SGYRY 432

Query: 1471 RSKGSWTLSTIDIGWGVSDCTAEAIK 1548
             S G+W  S I  G+ VSD T+EA++
Sbjct: 433  NSLGAWPFSNITQGYTVSDTTSEALR 458



 Score =  159 bits (401), Expect(3) = e-112
 Identities = 76/157 (48%), Positives = 102/157 (64%)
 Frame = +2

Query: 1571 HERRRTNSWLEDLNPSDSFQNIVIDHPSMECTSSVLEGLILFKEQYPHYRCKEIEKCIKN 1750
            +E  RT  W+E LNP++ F NI++++   ECT+SV+  L  F +  P YR  EIE  I+N
Sbjct: 498  YEPARTGEWMELLNPAEVFGNIMVEYSYPECTTSVILALRAFTKYDPGYRRDEIENTIEN 557

Query: 1751 AATYIENKQRKNGSWYGTWGICFTYGAFFAVKGLAASGRTYDNSDCMRKSCEFLLSKQQS 1930
            A  Y+   QR +GSWYG+W ICFTY A FA   LA++GR Y+N    +K+CEFLLSKQ+ 
Sbjct: 558  ALEYVVKMQRPDGSWYGSWAICFTYAAMFATGSLASAGRYYENCPVQKKACEFLLSKQRP 617

Query: 1931 TGGWGESYLSIETEEYVDSGSSHAVATAWAMLALIYA 2041
             GGW ESY++  T  Y ++ SS    T WA+ ALI A
Sbjct: 618  DGGWSESYMACVTGVYTETESSLVTQTGWALDALINA 654



 Score = 37.0 bits (84), Expect(3) = e-112
 Identities = 18/54 (33%), Positives = 26/54 (48%)
 Frame = +1

Query: 2050 PLYRAAKLLMNMQLDSGEFPQQEHMGCANSAFFFNYPNYRNIFPIMALGEFRRR 2211
            P+ +  K LM  Q   G + Q+   G  N      YPNY+  F I  LG+F ++
Sbjct: 661  PIEKGIKFLMASQKSDGSWQQKSMEGIFNKNVAIAYPNYKLYFSIYTLGKFAKQ 714

>P48449:ERG7_HUMAN Lanosterol synthase - Homo sapiens (Human)|
          Length = 732

 Score =  298 bits (764), Expect(2) = 2e-80
 Identities = 151/389 (38%), Positives = 227/389 (58%), Gaps = 3/389 (0%)
 Frame = +1

Query: 391  YCTLQAHDGHWPGDNSGIMFLMPMFIFSLYVTENLHSVISSDHQREICRHIYNHQNEDGG 570
            Y  LQA DGHW GD  G +FL+P  + + +V       + + ++ EI R++ + Q  DGG
Sbjct: 84   YVGLQAEDGHWTGDYGGPLFLLPGLLITCHVAR---IPLPAGYREEIVRYLRSVQLPDGG 140

Query: 571  WGTHVIGPSNMLCSCLNYAALRLLGEMLDCDNGALAKGRAWILSHGSATAVPQWGKIFLS 750
            WG H+   S +  + LNY +LR+LG  +  D+  L + R  +   G A A+P WGK +L+
Sbjct: 141  WGLHIEDKSTVFGTALNYVSLRILG--VGPDDPDLVRARNILHKKGGAVAIPSWGKFWLA 198

Query: 751  IIGAYDWVGNNPIFPELWMVPYFLPIHPGRFWCFCRMVYMSMAYLYGKKFVGPITPTILA 930
            ++  Y W G N +FPE+W+ P + P HP   WC CR VY+ M+Y Y  +      P + +
Sbjct: 199  VLNVYSWEGLNTLFPEMWLFPDWAPAHPSTLWCHCRQVYLPMSYCYAVRLSAAEDPLVQS 258

Query: 931  LREELYNIPYRNIDWNKARQSCAKEDCRCPHSKVQRTIFYCFHKFVEPVISSWPTNKLRE 1110
            LR+ELY   + +IDW   R + A ++   PHS + R ++   + +         +  LR+
Sbjct: 259  LRQELYVEDFASIDWLAQRNNVAPDELYTPHSWLLRVVYALLNLY-----EHHHSAHLRQ 313

Query: 1111 RALSKLMEHIHYNDETTEYITICPVDKALSMICCW-VENPNSYALKQHLPRVYDYMWLAE 1287
            RA+ KL EHI  +D  T+ I+I P+ K ++M+  W V+ P S A ++H+ R+ DY+W+  
Sbjct: 314  RAVQKLYEHIVADDRFTKSISIGPISKTINMLVRWYVDGPASTAFQEHVSRIPDYLWMGL 373

Query: 1288 DGMKAKIADGCQSWEISFIIQAFVST--DLIGEFSKTIEKAHDFLKNSQVISNCPSYQKN 1461
            DGMK +  +G Q W+ +F IQA +        EFS  ++KAH+FL+ SQV  N P YQK 
Sbjct: 374  DGMKMQGTNGSQIWDTAFAIQALLEAGGHHRPEFSSCLQKAHEFLRLSQVPDNPPDYQKY 433

Query: 1462 YRHRSKGSWTLSTIDIGWGVSDCTAEAIK 1548
            YR   KG ++ ST+D GW VSDCTAEA+K
Sbjct: 434  YRQMRKGGFSFSTLDCGWIVSDCTAEALK 462



 Score = 23.5 bits (49), Expect(2) = 2e-80
 Identities = 7/19 (36%), Positives = 14/19 (73%)
 Frame = +2

Query: 1658 ECTSSVLEGLILFKEQYPH 1714
            +CT+  L+ ++L +E+ PH
Sbjct: 455  DCTAEALKAVLLLQEKCPH 473



 Score =  139 bits (351), Expect(2) = 6e-40
 Identities = 64/158 (40%), Positives = 100/158 (63%), Gaps = 3/158 (1%)
 Frame = +2

Query: 1571 HERRRTNSWLEDLNPSDSFQNIVIDHPSMECTSSVLEGLILFKEQYPHYRCKEIEKCIKN 1750
            +E +R    LE LNPS+ F +I+ID+  +ECTS+V++ L  F +++P +R  EI + +  
Sbjct: 503  YETKRGGHLLELLNPSEVFGDIMIDYTYVECTSAVMQALKYFHKRFPEHRAAEIRETLTQ 562

Query: 1751 AATYIENKQRKNGSWYGTWGICFTYGAFFAVKGLAASGRTY-DNSDC--MRKSCEFLLSK 1921
               +   +QR +GSW G+WG+CFTYG +F ++  A  G+TY D + C  + ++C+FLLS+
Sbjct: 563  GLEFCRRQQRADGSWEGSWGVCFTYGTWFGLEAFACMGQTYRDGTACAEVSRACDFLLSR 622

Query: 1922 QQSTGGWGESYLSIETEEYVDSGSSHAVATAWAMLALI 2035
            Q + GGWGE + S E   Y+ S  S    T WAM+ L+
Sbjct: 623  QMADGGWGEDFESCEERRYLQSAQSQIHNTCWAMMGLM 660



 Score = 47.4 bits (111), Expect(2) = 6e-40
 Identities = 21/48 (43%), Positives = 30/48 (62%)
 Frame = +1

Query: 2059 RAAKLLMNMQLDSGEFPQQEHMGCANSAFFFNYPNYRNIFPIMALGEF 2202
            R  + L+  QL +G++PQ+   G  N +   +Y +YRNIFPI ALG F
Sbjct: 672  RGVRCLLEKQLPNGDWPQENIAGVFNKSCAISYTSYRNIFPIWALGRF 719

>Q04782:ERG7_CANAL Lanosterol synthase - Candida albicans (Yeast)|
          Length = 728

 Score =  210 bits (535), Expect = 2e-53
 Identities = 132/395 (33%), Positives = 198/395 (50%), Gaps = 12/395 (3%)
 Frame = +1

Query: 400  LQAHDGHWPGDNSGIMFLMPMFIFSLYVTENLHSV--ISSDHQREICRHIYNHQNE-DGG 570
            LQ  +G +P    G     PMF+   YVT N +S   I   ++ E+ R+I N  +  DGG
Sbjct: 80   LQLDNGIFPCQYKG-----PMFMTIGYVTANYYSKTEIPEPYRVEMIRYIVNTAHPVDGG 134

Query: 571  WGTHVIGPSNMLCSCLNYAALRLLGEMLDCDNGALAKGRAWILSHGSATAVPQWGKIFLS 750
            WG H +  S    + +NY  LRLLG  ++ D+  L K R  +   G A   P WGK +LS
Sbjct: 135  WGLHSVDKSTCFGTTMNYVCLRLLG--MEKDHPVLVKARKTLHRLGGAIKNPHWGKAWLS 192

Query: 751  IIGAYDWVGNNPIFPELWMVPYFLPIHPGRFWCFCRMVYMSMAYLYGKKFVGPITPTILA 930
            I+  Y+W G NP  PELW +PY+LPIHP ++W   R +Y+ + Y    +    + P +  
Sbjct: 193  ILNLYEWEGVNPAPPELWRLPYWLPIHPAKWWVHTRAIYLPLGYTSANRVQCELDPLLKE 252

Query: 931  LREELY---NIPYRNIDWNKARQSCAKEDCRCPHSKVQRTIFYCFHKFVEPVISSWPTNK 1101
            +R E+Y    +PY +I +   R +    D   PH+K+          F   ++S W   +
Sbjct: 253  IRNEIYVPSQLPYESIKFGNQRNNVCGVDLYYPHTKIL--------DFANSILSKWEAVR 304

Query: 1102 ---LRERALSKLMEHIHYNDETTEYITICPVDKALSM-ICCWVENPNSYALKQHLPRVYD 1269
               L      K+ + I    + TEY+ I PV  A +M + C  E   S   K+   R+ D
Sbjct: 305  PKWLLNWVNKKVYDLIVKEYQNTEYLCIAPVSFAFNMVVTCHYEGSESENFKKLQNRMND 364

Query: 1270 YMWLAEDGMKAKIADGCQSWEISFIIQAFVSTDLIGE--FSKTIEKAHDFLKNSQVISNC 1443
             ++    GM     +G Q W+ +F++Q F  T L+ +  +   I K++ FL  SQ   NC
Sbjct: 365  VLFHGPQGMTVMGTNGVQVWDAAFMVQYFFMTGLVDDPKYHDMIRKSYLFLVRSQFTENC 424

Query: 1444 PSYQKNYRHRSKGSWTLSTIDIGWGVSDCTAEAIK 1548
                 ++R R KG+W  ST + G+ VSDCTAEA+K
Sbjct: 425  --VDGSFRDRRKGAWPFSTKEQGYTVSDCTAEAMK 457



 Score =  142 bits (357), Expect(2) = 1e-39
 Identities = 66/147 (44%), Positives = 96/147 (65%), Gaps = 1/147 (0%)
 Frame = +2

Query: 1598 LEDLNPSDSFQNIVIDHPSMECTSSVLEGLILFKEQYPHYRCKEIEKCIKNAATYIENKQ 1777
            LE LNP++ F NI++++P +ECT S + GL  F + YP Y+ + I+K I +A  YI + Q
Sbjct: 513  LEKLNPAEVFNNIMVEYPYVECTDSSVLGLTYFAKYYPDYKPELIQKTISSAIQYILDSQ 572

Query: 1778 RK-NGSWYGTWGICFTYGAFFAVKGLAASGRTYDNSDCMRKSCEFLLSKQQSTGGWGESY 1954
               +GSWYG WGIC+TY + FA++ L   G  Y++S  ++K C+FL+SKQ   GGW ES 
Sbjct: 573  DNIDGSWYGCWGICYTYASMFALEALHTVGLDYESSSAVKKGCDFLISKQLPDGGWSESM 632

Query: 1955 LSIETEEYVDSGSSHAVATAWAMLALI 2035
               ET  YV+  +S  V +AWA++ LI
Sbjct: 633  KGCETHSYVNGENSLVVQSAWALIGLI 659



 Score = 44.3 bits (103), Expect(2) = 1e-39
 Identities = 20/54 (37%), Positives = 32/54 (59%)
 Frame = +1

Query: 2050 PLYRAAKLLMNMQLDSGEFPQQEHMGCANSAFFFNYPNYRNIFPIMALGEFRRR 2211
            P+ R  + LM  QL +GE+  ++  G  N +    YP+YR +FPI ALG ++ +
Sbjct: 668  PIKRGIQFLMKRQLPTGEWKYEDIEGVFNHSCAIEYPSYRFLFPIKALGLYKNK 721

>P38604:ERG7_YEAST Lanosterol synthase - Saccharomyces cerevisiae (Baker's yeast)|
          Length = 731

 Score =  203 bits (516), Expect = 3e-51
 Identities = 153/480 (31%), Positives = 231/480 (48%), Gaps = 18/480 (3%)
 Frame = +1

Query: 163  FDPELGTPEERAEVERLRRDYTRCRFEKRESQDLLMRMQYAKLNPLPAI--------VPK 318
            +   +G P+    + RLR D        RES + L   Q A   P             P+
Sbjct: 5    YSDTIGLPKTDPRLWRLRTDELG-----RESWEYLTPQQAANDPPSTFTQWLLQDPKFPQ 59

Query: 319  VHLDDNAEVTEEIISASLRQALNQYCTLQAHD-GHWPGDNSGIMFLMPMFIFSLYVTENL 495
             H + N    +     +     + +  LQ  D G +P    G     PMF+   YV  N 
Sbjct: 60   PHPERNKHSPDFSAFDACHNGASFFKLLQEPDSGIFPCQYKG-----PMFMTIGYVAVNY 114

Query: 496  HSVIS-SDHQR-EICRHIYNHQNE-DGGWGTHVIGPSNMLCSCLNYAALRLLGEMLDCDN 666
             + I   +H+R E+ R+I N  +  DGGWG H +  S +  + LNY  LRLLG  L  D+
Sbjct: 115  IAGIEIPEHERIELIRYIVNTAHPVDGGWGLHSVDKSTVFGTVLNYVILRLLG--LPKDH 172

Query: 667  GALAKGRAWILSHGSATAVPQWGKIFLSIIGAYDWVGNNPIFPELWMVPYFLPIHPGRFW 846
               AK R+ +L  G A   P WGKI+LS +  Y W G NP  PE W++PY LP+HPGR+W
Sbjct: 173  PVCAKARSTLLRLGGAIGSPHWGKIWLSALNLYKWEGVNPAPPETWLLPYSLPMHPGRWW 232

Query: 847  CFCRMVYMSMAYLYGKKFVGPITPTILALREELYNIPYRNIDWNKARQSCAKEDCRCPHS 1026
               R VY+ ++YL   KF  P+TP +  LR E+Y  P+  I+++K R +    D   PHS
Sbjct: 233  VHTRGVYIPVSYLSLVKFSCPMTPLLEELRNEIYTKPFDKINFSKNRNTVCGVDLYYPHS 292

Query: 1027 ---KVQRTIFYCFHKFVEPVISSWPTNKLRERALSKLMEHIHYNDETTEYITICPVDKAL 1197
                +  ++   + K++           +   +  K+ + I    + T+ + I PV++A 
Sbjct: 293  TTLNIANSLVVFYEKYLR-------NRFIYSLSKKKVYDLIKTELQNTDSLCIAPVNQAF 345

Query: 1198 -SMICCWVENPNSYALKQHLPRVYDYMWLAEDGMKAKIADGCQSWEISFIIQAFVSTDLI 1374
             +++    E  +S A ++   R  D ++    GM     +G Q+W+ +F IQ F    L 
Sbjct: 346  CALVTLIEEGVDSEAFQRLQYRFKDALFHGPQGMTIMGTNGVQTWDCAFAIQYFFVAGLA 405

Query: 1375 --GEFSKTIEKAHDFLKNSQVISNCPSYQKNYRHRSKGSWTLSTIDIGWGVSDCTAEAIK 1548
               EF  TI  A+ FL ++Q  + C     +YR + KG+W  ST   G+ V+DCTAEAIK
Sbjct: 406  ERPEFYNTIVSAYKFLCHAQFDTEC--VPGSYRDKRKGAWGFSTKTQGYTVADCTAEAIK 463



 Score =  153 bits (387), Expect(2) = 4e-42
 Identities = 74/157 (47%), Positives = 103/157 (65%)
 Frame = +2

Query: 1571 HERRRTNSWLEDLNPSDSFQNIVIDHPSMECTSSVLEGLILFKEQYPHYRCKEIEKCIKN 1750
            +E+ +    +E LNP++ F NI++++P +ECT S + GL  F  +Y  YR +EI   I+ 
Sbjct: 510  YEKIKAPLAMETLNPAEVFGNIMVEYPYVECTDSSVLGLTYF-HKYFDYRKEEIRTRIRI 568

Query: 1751 AATYIENKQRKNGSWYGTWGICFTYGAFFAVKGLAASGRTYDNSDCMRKSCEFLLSKQQS 1930
            A  +I+  Q  +GSWYG+WGICFTY   FA++ L   G TY+NS  +RK C+FL+SKQ  
Sbjct: 569  AIEFIKKSQLPDGSWYGSWGICFTYAGMFALEALHTVGETYENSSTVRKGCDFLVSKQMK 628

Query: 1931 TGGWGESYLSIETEEYVDSGSSHAVATAWAMLALIYA 2041
             GGWGES  S E   YVDS  S  V TAWA++AL++A
Sbjct: 629  DGGWGESMKSSELHSYVDSEKSLVVQTAWALIALLFA 665



 Score = 40.8 bits (94), Expect(2) = 4e-42
 Identities = 21/50 (42%), Positives = 28/50 (56%)
 Frame = +1

Query: 2059 RAAKLLMNMQLDSGEFPQQEHMGCANSAFFFNYPNYRNIFPIMALGEFRR 2208
            R   LL N Q +SGE+  +   G  N +    YP+YR +FPI ALG + R
Sbjct: 675  RGIDLLKNRQEESGEWKFESVEGVFNHSCAIEYPSYRFLFPIKALGMYSR 724

>P33247:SQHC_ALIAC Squalene--hopene cyclase - Alicyclobacillus acidocaldarius (Bacillus|
            acidocaldarius)
          Length = 631

 Score = 79.0 bits (193), Expect(2) = 7e-17
 Identities = 45/137 (32%), Positives = 69/137 (50%)
 Frame = +2

Query: 1637 VIDHPSMECTSSVLEGLILFKEQYPHYRCKEIEKCIKNAATYIENKQRKNGSWYGTWGIC 1816
            V D PS + T+ VLE        +  +   +  K I+ A  Y++ +Q+ +GSW+G WG+ 
Sbjct: 440  VTDPPSEDVTAHVLEC-------FGSFGYDDAWKVIRRAVEYLKREQKPDGSWFGRWGVN 492

Query: 1817 FTYGAFFAVKGLAASGRTYDNSDCMRKSCEFLLSKQQSTGGWGESYLSIETEEYVDSGSS 1996
            + YG    V  L A G        ++K+ +++   Q   GGWGE   S E   Y   G+S
Sbjct: 493  YLYGTGAVVSALKAVG-IDTREPYIQKALDWVEQHQNPDGGWGEDCRSYEDPAYAGKGAS 551

Query: 1997 HAVATAWAMLALIYAGQ 2047
                TAWA++ALI  G+
Sbjct: 552  TPSQTAWALMALIAGGR 568



 Score = 30.8 bits (68), Expect(2) = 7e-17
 Identities = 14/53 (26%), Positives = 27/53 (50%), Gaps = 1/53 (1%)
 Frame = +1

Query: 2059 RAAKLLMNMQLDSGEFPQQEHMGCANSA-FFFNYPNYRNIFPIMALGEFRRRL 2214
            R  + L+  Q   G + +  + G      F+  Y  YR++FP +ALG +++ +
Sbjct: 576  RGVQYLVETQRPDGGWDEPYYTGTGFPGDFYLGYTMYRHVFPTLALGRYKQAI 628



 Score = 59.3 bits (142), Expect = 7e-08
 Identities = 38/195 (19%), Positives = 92/195 (47%), Gaps = 5/195 (2%)
 Frame = +1

Query: 343 VTEEIISA-----SLRQALNQYCTLQAHDGHWPGDNSGIMFLMPMFIFSLYVTENLHSVI 507
           + E+++ A     +L +A+    + Q  +G+W G     + +   ++   ++ +     +
Sbjct: 1   MAEQLVEAPAYARTLDRAVEYLLSCQKDEGYWWGPLLSNVTMEAEYVLLCHILDR----V 56

Query: 508 SSDHQREICRHIYNHQNEDGGWGTHVIGPSNMLCSCLNYAALRLLGEMLDCDNGALAKGR 687
             D   +I R++ + Q EDG W  +  GP ++  +   Y AL+ +G  +  D   + K  
Sbjct: 57  DRDRMEKIRRYLLHEQREDGTWALYPGGPPDLDTTIEAYVALKYIG--MSRDEEPMQKAL 114

Query: 688 AWILSHGSATAVPQWGKIFLSIIGAYDWVGNNPIFPELWMVPYFLPIHPGRFWCFCRMVY 867
            +I S G   +   + +++L+++G Y W     + PE+  +   +P++   F  + R   
Sbjct: 115 RFIQSQGGIESSRVFTRMWLALVGEYPWEKVPMVPPEIMFLGKRMPLNIYEFGSWARATV 174

Query: 868 MSMAYLYGKKFVGPI 912
           ++++ +  ++ V P+
Sbjct: 175 VALSIVMSRQPVFPL 189

>P54924:SQHC_BRAJA Squalene--hopene cyclase - Bradyrhizobium japonicum|
          Length = 660

 Score = 72.8 bits (177), Expect = 6e-12
 Identities = 43/138 (31%), Positives = 71/138 (51%), Gaps = 1/138 (0%)
 Frame = +2

Query: 1637 VIDHPSMECTSSVLEGLILFKEQYPHYRCKEIEKCIKNAATYIENKQRKNGSWYGTWGIC 1816
            ++D P+ + T+  +  L    E        +  K + +   Y+   Q   GSWYG WG+ 
Sbjct: 459  LLDPPTEDVTARCVSMLAQLGET------AKTSKHVADGVAYLRKTQHPEGSWYGRWGMN 512

Query: 1817 FTYGAFFAVKGLAASGRTYDNSDCMRKSCEFLLSKQQSTGGWGESYLSIETE-EYVDSGS 1993
            F YG +  +  L  +G  +D+   +RK+ ++L S Q   GGWGE  +S   + +  ++  
Sbjct: 513  FIYGTWSVLCALNMAGVRHDD-PMIRKAADWLASIQNKDGGWGEDAVSYRLDYKGWEAAP 571

Query: 1994 SHAVATAWAMLALIYAGQ 2047
            S A  TAWA+LAL+ AG+
Sbjct: 572  STASQTAWALLALMAAGE 589

>P55348:SQHC_RHISN Probable squalene--hopene cyclase - Rhizobium sp. (strain NGR234)|
          Length = 647

 Score = 71.2 bits (173), Expect = 2e-11
 Identities = 39/109 (35%), Positives = 58/109 (53%), Gaps = 2/109 (1%)
 Frame = +2

Query: 1736 KCIKNAATYIENKQRKNGSWYGTWGICFTYGAFFAVKGLAASGRTYDNSDCM-RKSCEFL 1912
            K +     Y+   Q   GSWYG WG+ + YG +  +  L A+G   D+ D M RK+ E+L
Sbjct: 480  KAVAEGIAYLRRTQHAEGSWYGRWGLNYIYGTWSVLCALNAAG--IDHQDPMIRKAVEWL 537

Query: 1913 LSKQQSTGGWGESYLSIETE-EYVDSGSSHAVATAWAMLALIYAGQCHY 2056
            +S Q   GGWGE  +S   +    +   S +  TAWA+L L+ AG+  +
Sbjct: 538  VSIQSWDGGWGEDAISYRLDYSGYEQAPSTSSQTAWALLGLMAAGEVEH 586

>P33990:SQHC_ZYMMO Squalene--hopene cyclase - Zymomonas mobilis|
          Length = 658

 Score = 62.8 bits (151), Expect = 7e-09
 Identities = 37/108 (34%), Positives = 61/108 (56%), Gaps = 4/108 (3%)
 Frame = +2

Query: 1742 IKNAATYIENKQRKNGSWYGTWGICFTYGAFFAVKGLAASGRTYDNSDCMRKSCEFLLSK 1921
            +K A  Y+  +Q ++GSW+G WG+ + YG + A+  L  +   +D+   ++K+  +L + 
Sbjct: 486  MKAAVDYLLKEQEEDGSWFGRWGVNYIYGTWSALCALNVAALPHDHL-AIQKAVAWLKTI 544

Query: 1922 QQSTGGWGE---SY-LSIETEEYVDSGSSHAVATAWAMLALIYAGQCH 2053
            Q   GGWGE   SY L     E +DS +S    TAWA+L L+  G+ +
Sbjct: 545  QNEDGGWGENCDSYALDYSGYEPMDSTASQ---TAWALLGLMAVGEAN 589

>Q9X079:Y984_THEMA UPF0192 protein TM_0984 precursor - Thermotoga maritima|
          Length = 1536

 Score = 35.4 bits (80), Expect = 1.1
 Identities = 30/105 (28%), Positives = 46/105 (43%), Gaps = 1/105 (0%)
 Frame = +1

Query: 487  ENLHSVISSDHQREICRHIYNHQNEDGGWGTHVIGPSNMLCSCLNYAALRL-LGEMLDCD 663
            ENL  +I    QR + + +Y++Q+ DGGWG    G S+   +C     L   +    D  
Sbjct: 941  ENLEEII----QRGLFK-LYSYQHNDGGWGWFRFGESDDFMTCYVMEGLYFTMKAGYDVA 995

Query: 664  NGALAKGRAWILSHGSATAVPQWGKIFLSIIGAYDWVGNNPIFPE 798
               L +G  ++  H SA     +G   L + G    V + P  PE
Sbjct: 996  ESVLQRGIEYLRKHPSA-----YGSYVLDLYG----VNHEPFKPE 1031

>Q00204:PALB_EMENI Calpain-like protease palB - Emericella nidulans (Aspergillus|
           nidulans)
          Length = 847

 Score = 33.5 bits (75), Expect = 4.2
 Identities = 19/64 (29%), Positives = 29/64 (45%), Gaps = 4/64 (6%)
 Frame = +1

Query: 769 WVGNNPIFPELWMVPYFLP----IHPGRFWCFCRMVYMSMAYLYGKKFVGPITPTILALR 936
           W G + ++P L+  P   P    + PG FW  C MV  +   LY         P I A +
Sbjct: 388 WAGTDAVYPALFADPGPFPNSPFLSPGTFWMDCEMVLQNFENLYLN-----WNPGIFAYQ 442

Query: 937 EELY 948
           E+++
Sbjct: 443 EDIH 446

>Q1QZ34:OSTA_CHRSD LPS-assembly protein precursor - Chromohalobacter salexigens (strain|
            DSM 3043 / ATCC BAA-138 / NCIMB 13768)
          Length = 821

 Score = 33.5 bits (75), Expect = 4.2
 Identities = 25/86 (29%), Positives = 40/86 (46%), Gaps = 7/86 (8%)
 Frame = +1

Query: 1270 YMWLAE-----DGMKAKIADGCQSWEISFIIQAFVSTDLIGEF--SKTIEKAHDFLKNSQ 1428
            Y W  E     D  + ++    + +++SF  QA  S DLIG F    T ++A + L   Q
Sbjct: 696  YSWQLEGFEPADDAEDRLGYNREDYDVSFAYQATPSLDLIGRFLYDNTNDRAMEQLAGVQ 755

Query: 1429 VISNCPSYQKNYRHRSKGSWTLSTID 1506
                C + Q  +R   + + T +TID
Sbjct: 756  FNDCCSAVQLVWREWIEDNDTANTID 781

>Q8KA87:CLPB2_CHLTE Probable chaperone clpB 2 - Chlorobium tepidum|
          Length = 442

 Score = 33.5 bits (75), Expect = 4.2
 Identities = 18/50 (36%), Positives = 28/50 (56%)
 Frame = +2

Query: 1625 FQNIVIDHPSMECTSSVLEGLILFKEQYPHYRCKEIEKCIKNAATYIENK 1774
            FQ +++D PS+E T S+L GL   KE+Y  +    I+     AA  + N+
Sbjct: 336  FQTVIVDQPSVEDTVSILRGL---KEKYEIHHGVRIKDAALVAAAELSNR 382

>Q73II8:PTH_WOLPM Peptidyl-tRNA hydrolase - Wolbachia pipientis wMel|
          Length = 182

 Score = 33.1 bits (74), Expect = 5.5
 Identities = 21/59 (35%), Positives = 30/59 (50%), Gaps = 4/59 (6%)
 Frame = +1

Query: 76  LEMWRLKVSEGGSP----WLRSPSSFLGRAVWEFDPELGTPEERAEVERLRRDYTRCRF 240
           LE+ R+KV +GGS      L+S  SF+G   W     +G PE+    +R   DY   +F
Sbjct: 95  LELGRIKVKKGGSSAGHNGLKSIDSFIGNDYWRLRFGVGRPED----QRSLADYVLSKF 149

>P19467:MUC13_MOUSE Mucin-13 precursor - Mus musculus (Mouse)|
          Length = 573

 Score = 33.1 bits (74), Expect = 5.5
 Identities = 24/80 (30%), Positives = 33/80 (41%)
 Frame = -1

Query: 298 GGLILHTACA*EDPVTPSSRNGTACSLGATSQPLRVPPAYRAQDQTPTPLYRGSYSGNAA 119
           GG    T    + P + S  + T  S G  S P  V      Q Q+P    + S + +++
Sbjct: 111 GGASPPTTVQSQSPGSSSQASTTTSSSGGASPPTTV------QSQSPGSSSQASTTTSSS 164

Query: 118 TGCRPPTPSASTSPGDQRTV 59
            G  PPT   S SPG    V
Sbjct: 165 GGASPPTTVQSQSPGSSSQV 184



 Score = 32.3 bits (72), Expect = 9.4
 Identities = 23/75 (30%), Positives = 32/75 (42%)
 Frame = -1

Query: 298 GGLILHTACA*EDPVTPSSRNGTACSLGATSQPLRVPPAYRAQDQTPTPLYRGSYSGNAA 119
           GG    T    + P + S  + T  S G  S P  V      Q Q+P    + S + +++
Sbjct: 30  GGTSPPTTVQSQSPGSSSQASTTTSSSGGASPPTTV------QSQSPGSSSQASTTTSSS 83

Query: 118 TGCRPPTPSASTSPG 74
            G  PPT   S SPG
Sbjct: 84  GGASPPTTVQSQSPG 98



 Score = 32.3 bits (72), Expect = 9.4
 Identities = 23/75 (30%), Positives = 32/75 (42%)
 Frame = -1

Query: 298 GGLILHTACA*EDPVTPSSRNGTACSLGATSQPLRVPPAYRAQDQTPTPLYRGSYSGNAA 119
           GG    T    + P + S  + T  S G  S P  V      Q Q+P    + S + +++
Sbjct: 57  GGASPPTTVQSQSPGSSSQASTTTSSSGGASPPTTV------QSQSPGSSSQASTTTSSS 110

Query: 118 TGCRPPTPSASTSPG 74
            G  PPT   S SPG
Sbjct: 111 GGASPPTTVQSQSPG 125



 Score = 32.3 bits (72), Expect = 9.4
 Identities = 23/75 (30%), Positives = 32/75 (42%)
 Frame = -1

Query: 298 GGLILHTACA*EDPVTPSSRNGTACSLGATSQPLRVPPAYRAQDQTPTPLYRGSYSGNAA 119
           GG    T    + P + S  + T  S G  S P  V      Q Q+P    + S + +++
Sbjct: 84  GGASPPTTVQSQSPGSSSQASTTTSSSGGASPPTTV------QSQSPGSSSQASTTTSSS 137

Query: 118 TGCRPPTPSASTSPG 74
            G  PPT   S SPG
Sbjct: 138 GGASPPTTVQSQSPG 152

>O74689:NDE1_EMENI Nuclear distribution protein nudE - Emericella nidulans|
           (Aspergillus nidulans)
          Length = 586

 Score = 32.7 bits (73), Expect = 7.2
 Identities = 25/67 (37%), Positives = 31/67 (46%), Gaps = 3/67 (4%)
 Frame = -1

Query: 250 PSSRNGTACSLGATSQPLRVPPAYR---AQDQTPTPLYRGSYSGNAATGCRPPTPSASTS 80
           PSSR   + SL  ++ P  V P+ R    Q +T TPL  G YS N  T  R P  S S  
Sbjct: 438 PSSRTSFSSSLSHSTHP-SVTPSNRPESRQSRTKTPL--GHYSTNPTTESRRPRSSLSNP 494

Query: 79  PGDQRTV 59
            G    +
Sbjct: 495 AGQSTPI 501

>Q8TAX7:MUC7_HUMAN Mucin-7 precursor - Homo sapiens (Human)|
          Length = 377

 Score = 32.7 bits (73), Expect = 7.2
 Identities = 25/71 (35%), Positives = 29/71 (40%), Gaps = 5/71 (7%)
 Frame = -1

Query: 259 PVTPSSRNGTACSLGATSQPLRVPPAYRAQDQTPTPLYRGSYSGNAATGCRPPTPSAST- 83
           P TPS+      S  A  +   VPP   A    P+     S S    T   PPTPSA+T 
Sbjct: 238 PPTPSATTPAPLSSSAPPETTAVPPTPSATTLDPS-----SASAPPETTAAPPTPSATTP 292

Query: 82  ----SPGDQRT 62
               SP  Q T
Sbjct: 293 APPSSPAPQET 303

>Q21955:MED15_CAEEL RNA polymerase II mediator complex subunit 15 - Caenorhabditis|
           elegans
          Length = 780

 Score = 32.7 bits (73), Expect = 7.2
 Identities = 28/89 (31%), Positives = 35/89 (39%)
 Frame = -1

Query: 322 ALLGQLPEGGLILHTACA*EDPVTPSSRNGTACSLGATSQPLRVPPAYRAQDQTPTPLYR 143
           ALLG  P GG   + A    DP   S++        AT+Q    P A       P P   
Sbjct: 94  ALLGNTPAGGTPGYRAPVPPDPQPTSAQARNPPVTVATTQASTTPSAPNPPGGLPAP-SA 152

Query: 142 GSYSGNAATGCRPPTPSASTSPGDQRTVG 56
            + +  AA     P+P  S  PG Q T G
Sbjct: 153 SATAAVAAAVASFPSPDTSIRPGGQITPG 181

>Q839C1:LDH1_ENTFA L-lactate dehydrogenase 1 - Enterococcus faecalis (Streptococcus|
           faecalis)
          Length = 327

 Score = 32.3 bits (72), Expect = 9.4
 Identities = 19/68 (27%), Positives = 30/68 (44%)
 Frame = +1

Query: 640 LGEMLDCDNGALAKGRAWILSHGSATAVPQWGKIFLSIIGAYDWVGNNPIFPELWMVPYF 819
           + E++D D   +    A+IL     T  P W    ++ +  Y+WV NNP   E  MV  F
Sbjct: 163 IAELVDVDARNV---HAYILGEHGDTEFPVWSHANVAGLQIYEWVKNNPDVDEEAMVNLF 219

Query: 820 LPIHPGRF 843
             +    +
Sbjct: 220 FNVRDAAY 227


  Database: uniprot_sprot.fasta.out
    Posted date:  Jul 19, 2007  5:58 PM
  Number of letters in database: 100,686,439
  Number of sequences in database:  274,295
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 274295
Number of Hits to DB: 442,712,676
Number of extensions: 10247136
Number of successful extensions: 26643
Number of sequences better than 10.0: 23
Number of HSP's gapped: 26573
Number of HSP's successfully gapped: 48
Length of query: 806
Length of database: 100,686,439
Length adjustment: 121
Effective length of query: 685
Effective length of database: 67,496,744
Effective search space: 46235269640
Effective search space used: 46235269640
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)