ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | FLbaf115l11 |
|---|---|
| Clone Library Name | barley_pub |
>Q05609:CTR1_ARATH Serine/threonine-protein kinase CTR1 - Arabidopsis thaliana| (Mouse-ear cress) Length = 821 Score = 164 bits (416), Expect = 9e-40 Identities = 119/337 (35%), Positives = 171/337 (50%), Gaps = 11/337 (3%) Frame = +1 Query: 13 GSSPPSSTCREGPLPSKRYRCAAMQPSAGPGTGAAIHDPF-GVAKGFVGLE-----IPAE 174 GS PPS+ +P + A+ Q A P I P A +GL+ IP Sbjct: 495 GSLPPSAN-----MPPQNMMRASNQIEAAPMNAPPISQPVPNRANRELGLDGDDMDIPWC 549 Query: 175 QLIIEEELSKDKDGEDIGRFGKVFKGRCFGLEVAVKIPKVQELSPEQLEKFKQEVAINSE 354 L I+E++ G FG V + G +VAVKI Q+ E++ +F +EVAI Sbjct: 550 DLNIKEKIGA-------GSFGTVHRAEWHGSDVAVKILMEQDFHAERVNEFLREVAIMKR 602 Query: 355 INHPNVVRFLGACLKPLNFRLVTE--XXXXXXXXXXXSNKARPLSLARRMRIARDIVKGM 528 + HPN+V F+GA +P N +VTE S L RR+ +A D+ KGM Sbjct: 603 LRHPNIVLFMGAVTQPPNLSIVTEYLSRGSLYRLLHKSGAREQLDERRRLSMAYDVAKGM 662 Query: 529 IYIHAAN--LVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHG-GPKGTPLWMAP 699 Y+H N +VH DLK N+L+D T K+ DFGL+ RL + L GTP WMAP Sbjct: 663 NYLHNRNPPIVHRDLKSPNLLVDKKYTVKVCDFGLS--RLKASTFLSSKSAAGTPEWMAP 720 Query: 700 EMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQK 879 E+L +P +EK+D+YSFG+ILW+L T + AV R +P+ N + Sbjct: 721 EVLRDEPSNEKSDVYSFGVILWELAT-LQQPWGNLNPAQVVAAVGFKCKRLEIPRNLNPQ 779 Query: 880 LSYLIHRCWHPQPALRPSFTEIDNAYLQPIIVETAIP 990 ++ +I CW +P RPSF I + L+P+I ++A+P Sbjct: 780 VAAIIEGCWTNEPWKRPSFATIMD-LLRPLI-KSAVP 814
>Q7T6Y2:YR831_MIMIV Putative serine/threonine-protein kinase/receptor R831 precursor -| Mimivirus Length = 1624 Score = 158 bits (399), Expect = 8e-38 Identities = 84/243 (34%), Positives = 136/243 (55%), Gaps = 2/243 (0%) Frame = +1 Query: 223 IGRFGKVFKGRCFGLEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGACLKP 402 +G +G VF G+ G++VAVK Q+LS QL +F+ E+A SE+ H N+V F+GAC+K Sbjct: 1372 LGSYGIVFNGKWKGVDVAVKKFVKQKLSETQLLEFRAEMAFLSELKHSNIVTFIGACIKK 1431 Query: 403 LNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAAN--LVHLDLKPE 576 N +VTE N ++ A ++++ G+ Y+H++N +VH D+KP Sbjct: 1432 PNICIVTEYMRMGNLRDVLKNPDIKITFANKLKLLYGAAMGIDYLHSSNPMIVHRDIKPA 1491 Query: 577 NVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWMAPEMLLGKPFDEKADIYSFGI 756 N+L+D + KIADFG I+ D ++ GTP W APE++ G+ + EKAD++SFG+ Sbjct: 1492 NILVDEHFNVKIADFGFARIKEDNTTMTR---CGTPCWTAPEVIRGEKYCEKADVFSFGV 1548 Query: 757 ILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPALRPSF 936 ++W++LT + + RP +P + + LI +CWH + RP+ Sbjct: 1549 VMWEVLT--GKEPFAECNFMKVSLDILEGGRPIIPSDCPHEFAKLIKKCWHAKAHKRPTM 1606 Query: 937 TEI 945 TE+ Sbjct: 1607 TEV 1609 Score = 134 bits (338), Expect = 1e-30 Identities = 91/264 (34%), Positives = 139/264 (52%), Gaps = 11/264 (4%) Frame = +1 Query: 187 EEELSKDKDGEDIGR--FGKVFKGRCFGLEVAVKIPKVQELSPEQLEKFKQEVAINSEIN 360 E + S+ + GE +G +G+V+K G EVAVK+ + +S + F +EV I + + Sbjct: 780 EIDFSELEIGETLGTGGYGEVYKSIWKGTEVAVKLISSKHVSKDMERSFFEEVKIMTSLR 839 Query: 361 HPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNKARP-LSLARRMRIARDIVKGMIYI 537 HPNVV F+ A K N +V E N+ P + A ++++A KGM ++ Sbjct: 840 HPNVVLFMAASTKSPNMCIVMEFMSLGSLYDLLGNELIPEIPYALKIKMAYQASKGMHFL 899 Query: 538 HAANLVHLDLKPENVLLDFNGTAKIADFGLTVIR--LDRQSLLHGGPKGTPLWMAPEMLL 711 H++ +VH DLK N+LLD K++DFGLT ++ LD++ + GT W+APE+L Sbjct: 900 HSSGIVHRDLKSLNLLLDSKWNVKVSDFGLTKVKSELDKKK-TNDNIIGTIHWIAPEILN 958 Query: 712 GKPFDE--KADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQG--TNQK 879 + AD+YSFGIILW+LLTR + + + RPP+ T Sbjct: 959 DSTEVDYILADVYSFGIILWELLTREQPYKGMTPAAIAVSVIR-DGMRPPISDEAVTAHS 1017 Query: 880 LSY--LIHRCWHPQPALRPSFTEI 945 + Y LI +CWH +RP+F EI Sbjct: 1018 IEYIDLIKQCWHSDTIIRPTFLEI 1041
>Q2MHE4:HT1_ARATH Serine/threonine-protein kinase HT1 - Arabidopsis thaliana| (Mouse-ear cress) Length = 390 Score = 157 bits (397), Expect = 1e-37 Identities = 93/238 (39%), Positives = 134/238 (56%), Gaps = 3/238 (1%) Frame = +1 Query: 241 VFKGRCFGLEVAVKIPKVQELSPEQLEK-FKQEVAINSEINHPNVVRFLGACLKPLNFRL 417 ++K R +++ V+IP +E + +LE+ FK EVA+ S + HPN+V+F+ AC KP + + Sbjct: 104 IYKQRAVAVKM-VRIPTHKEETRAKLEQQFKSEVALLSRLFHPNIVQFIAACKKPPVYCI 162 Query: 418 VTEXXXXXXXXXXXSNKARPLSLARR--MRIARDIVKGMIYIHAANLVHLDLKPENVLLD 591 +TE NK P SL+ +R+A DI +GM Y+H+ ++H DLK N+LL+ Sbjct: 163 ITEYMSQGNLRMYL-NKKEPYSLSIETVLRLALDISRGMEYLHSQGVIHRDLKSNNLLLN 221 Query: 592 FNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWMAPEMLLGKPFDEKADIYSFGIILWQL 771 K+ADFG + L+ Q G GT WMAPEM+ KP+ K D+YSFGI+LW+L Sbjct: 222 DEMRVKVADFGTSC--LETQCREAKGNMGTYRWMAPEMIKEKPYTRKVDVYSFGIVLWEL 279 Query: 772 LTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPALRPSFTEI 945 T AVA N RPP+P L++LI RCW P+ RP F+ I Sbjct: 280 TTALLPFQGMTPVQAAF-AVAEKNERPPLPASCQPALAHLIKRCWSENPSKRPDFSNI 336
>Q7T6X2:YR826_MIMIV Putative serine/threonine-protein kinase/receptor R826 precursor -| Mimivirus Length = 1657 Score = 142 bits (357), Expect = 6e-33 Identities = 77/250 (30%), Positives = 134/250 (53%), Gaps = 4/250 (1%) Frame = +1 Query: 208 KDGEDIG--RFGKVFKGRCFGLEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRF 381 K GE IG +G V++G+ ++VA+K Q++ L ++E+A +++HPN++ Sbjct: 1400 KMGEQIGLGSYGVVYRGKWKNVDVAIKKFIKQKIDENHLLGIREEIAFLKKLHHPNIITM 1459 Query: 382 LGACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAAN--LV 555 +GA LK N +VTE L ++++I +I KG+ Y+H+ + ++ Sbjct: 1460 VGASLKKPNICIVTEYMAKGNLRDAMRTCTPKLEWHQKIKILVNIAKGISYLHSFDPPII 1519 Query: 556 HLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWMAPEMLLGKPFDEKA 735 H D+KP N+L+D N KIADFG I+ + + G TP W APE++ +DEK Sbjct: 1520 HRDIKPSNILIDENWNVKIADFGFARIKEENAIMTRCG---TPCWTAPEIIRNDIYDEKV 1576 Query: 736 DIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQ 915 D++SFGI++W++LT I + + RP +PQ ++ + L+ +CWH + Sbjct: 1577 DVFSFGIVMWEVLT--CKEPFIGANFMKITMDILEDVRPKIPQDCPEEFAKLMRKCWHAK 1634 Query: 916 PALRPSFTEI 945 RP+ ++ Sbjct: 1635 STKRPTMDDV 1644 Score = 138 bits (348), Expect = 7e-32 Identities = 91/270 (33%), Positives = 138/270 (51%), Gaps = 8/270 (2%) Frame = +1 Query: 160 EIPAEQLIIEEELSKDKDGEDIGRFGKVFKGRCFGLEVAVKIPKVQELSPEQLEK-FKQE 336 EI +L + E+L G FG+V KG G EVAVK+ + + +E+ FK E Sbjct: 780 EIDFHELELGEQLGT-------GAFGEVHKGTWRGTEVAVKMISPDKTITKDIERNFKDE 832 Query: 337 VAINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNKARP-LSLARRMRIARD 513 V + + + HPNVV F+ A KP +V E N+ P + A +++IA Sbjct: 833 VRVMTTLRHPNVVLFMAASTKPPKMCIVMEFMALGSLHDLLKNELIPDIPFALKVKIAYQ 892 Query: 514 IVKGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWM 693 KGM ++H++ + H DLK N+LLD K++DFGLT + D +S+ GT W Sbjct: 893 ASKGMHFLHSSGITHRDLKSLNLLLDIKWNVKVSDFGLTKFKSDVKSINPEKFAGTIQWT 952 Query: 694 APEMLL-GKPFDE-KADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQG 867 APE+L + D +D+YSFGII+W+L+TR + + +NYRP + Sbjct: 953 APEILSEDREVDYILSDVYSFGIIMWELITRDQPYFGMSPAAIAVSVIR-DNYRPVISDQ 1011 Query: 868 TNQKLS----YLIHRCWHPQPALRPSFTEI 945 +++ L+ CWH P +RP+F EI Sbjct: 1012 LRSEVAPEYIELLTSCWHFDPTIRPTFLEI 1041
>P00521:ABL_MLVAB Tyrosine-protein kinase transforming protein Abl - Abelson murine| leukemia virus Length = 746 Score = 133 bits (334), Expect = 3e-30 Identities = 84/267 (31%), Positives = 133/267 (49%), Gaps = 3/267 (1%) Frame = +1 Query: 226 GRFGKVFKG--RCFGLEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGACLK 399 G++G+V++G + + L VAVK K + ++E+F +E A+ EI HPN+V+ LG C + Sbjct: 137 GQYGEVYEGVWKKYSLTVAVKTLKEDTM---EVEEFLKEAAVMKEIKHPNLVQLLGVCTR 193 Query: 400 PLNFRLVTEXXXXXXXXXXXSNKARP-LSLARRMRIARDIVKGMIYIHAANLVHLDLKPE 576 F ++TE R +S + +A I M Y+ N +H DL Sbjct: 194 EPPFYIITEFMTYGNLLDYLRECNRQEVSAVVLLYMATQISSAMEYLEKKNFIHRDLAAR 253 Query: 577 NVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWMAPEMLLGKPFDEKADIYSFGI 756 N L+ N K+ADFGL+ + H G K W APE L F K+D+++FG+ Sbjct: 254 NCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGV 313 Query: 757 ILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPALRPSF 936 +LW++ T + + +YR P+G +K+ L+ CW P+ RPSF Sbjct: 314 LLWEIAT-YGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSF 372 Query: 937 TEIDNAYLQPIIVETAIPDEVGRVLWK 1017 EI A+ + + E++I DEV + L K Sbjct: 373 AEIHQAF-ETMFQESSISDEVEKELGK 398
>P00520:ABL1_MOUSE Proto-oncogene tyrosine-protein kinase ABL1 - Mus musculus (Mouse)| Length = 1123 Score = 133 bits (334), Expect = 3e-30 Identities = 84/267 (31%), Positives = 133/267 (49%), Gaps = 3/267 (1%) Frame = +1 Query: 226 GRFGKVFKG--RCFGLEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGACLK 399 G++G+V++G + + L VAVK K + ++E+F +E A+ EI HPN+V+ LG C + Sbjct: 251 GQYGEVYEGVWKKYSLTVAVKTLKEDTM---EVEEFLKEAAVMKEIKHPNLVQLLGVCTR 307 Query: 400 PLNFRLVTEXXXXXXXXXXXSNKARP-LSLARRMRIARDIVKGMIYIHAANLVHLDLKPE 576 F ++TE R +S + +A I M Y+ N +H DL Sbjct: 308 EPPFYIITEFMTYGNLLDYLRECNRQEVSAVVLLYMATQISSAMEYLEKKNFIHRDLAAR 367 Query: 577 NVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWMAPEMLLGKPFDEKADIYSFGI 756 N L+ N K+ADFGL+ + H G K W APE L F K+D+++FG+ Sbjct: 368 NCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGV 427 Query: 757 ILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPALRPSF 936 +LW++ T + + +YR P+G +K+ L+ CW P+ RPSF Sbjct: 428 LLWEIAT-YGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSF 486 Query: 937 TEIDNAYLQPIIVETAIPDEVGRVLWK 1017 EI A+ + + E++I DEV + L K Sbjct: 487 AEIHQAF-ETMFQESSISDEVEKELGK 512
>P00519:ABL1_HUMAN Proto-oncogene tyrosine-protein kinase ABL1 - Homo sapiens (Human)| Length = 1130 Score = 132 bits (331), Expect = 6e-30 Identities = 83/267 (31%), Positives = 133/267 (49%), Gaps = 3/267 (1%) Frame = +1 Query: 226 GRFGKVFKG--RCFGLEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGACLK 399 G++G+V++G + + L VAVK K + ++E+F +E A+ EI HPN+V+ LG C + Sbjct: 251 GQYGEVYEGVWKKYSLTVAVKTLKEDTM---EVEEFLKEAAVMKEIKHPNLVQLLGVCTR 307 Query: 400 PLNFRLVTEXXXXXXXXXXXSNKARP-LSLARRMRIARDIVKGMIYIHAANLVHLDLKPE 576 F ++TE R ++ + +A I M Y+ N +H DL Sbjct: 308 EPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAAR 367 Query: 577 NVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWMAPEMLLGKPFDEKADIYSFGI 756 N L+ N K+ADFGL+ + H G K W APE L F K+D+++FG+ Sbjct: 368 NCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGV 427 Query: 757 ILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPALRPSF 936 +LW++ T + + +YR P+G +K+ L+ CW P+ RPSF Sbjct: 428 LLWEIAT-YGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSF 486 Query: 937 TEIDNAYLQPIIVETAIPDEVGRVLWK 1017 EI A+ + + E++I DEV + L K Sbjct: 487 AEIHQAF-ETMFQESSISDEVEKELGK 512
>Q5UQG7:YR818_MIMIV Putative serine/threonine-protein kinase/receptor R818 precursor -| Mimivirus Length = 1651 Score = 130 bits (328), Expect = 1e-29 Identities = 72/243 (29%), Positives = 126/243 (51%), Gaps = 2/243 (0%) Frame = +1 Query: 223 IGRFGKVFKGRCFGLEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGACLKP 402 +G +G V G+ + VAVK Q++ +Q+ +F+ E+A S++ HP+++ +GACLK Sbjct: 1402 VGSYGIVNMGKWKNINVAVKKFVKQKIDEKQMLEFRAEIAFLSQLRHPHIILMIGACLKR 1461 Query: 403 LNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAAN--LVHLDLKPE 576 N +VTE L ++++ G+ Y+H ++ ++H D+KP Sbjct: 1462 PNICIVTEFMGNGSLRNVIKTTKPEWKL--KIKMLYQTALGIGYLHNSDPIIIHRDIKPS 1519 Query: 577 NVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWMAPEMLLGKPFDEKADIYSFGI 756 N+L+D + KIADFG I+ + + GTP W APE++ G+ + EK D++SFGI Sbjct: 1520 NILVDDSMNVKIADFGFARIKEENSVMTR---CGTPCWTAPEIIRGEKYTEKVDVFSFGI 1576 Query: 757 ILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPALRPSF 936 ++W++LT + + RP +P + L+ +CWH +P RPS Sbjct: 1577 VMWEVLT--CKEPFSGCNFMKVSMDILEGARPQIPSDCPIDFTKLMKQCWHAKPDKRPSM 1634 Query: 937 TEI 945 ++ Sbjct: 1635 EDV 1637 Score = 126 bits (316), Expect = 3e-28 Identities = 86/249 (34%), Positives = 126/249 (50%), Gaps = 9/249 (3%) Frame = +1 Query: 226 GRFGKVFKGRCFGLEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGACLKPL 405 G G+VFK G EVAVK ++ + FKQE+ + + HPNVV F+ A +P Sbjct: 802 GGSGEVFKAMWKGTEVAVKKLVNSNITKDAERNFKQEIHRMTSLRHPNVVLFMAASTRPP 861 Query: 406 NFRLVTEXXXXXXXXXXXSNK-ARPLSLARRMRIARDIVKGMIYIHAANLVHLDLKPENV 582 N +V E N+ + R+RIA KGM ++H++++VH DLK N+ Sbjct: 862 NMCIVMEFMSLGSLYDLLGNELVTEIPPVLRIRIAYQAAKGMHFLHSSDIVHRDLKSLNL 921 Query: 583 LLDFNGTAKIADFGLTVIRLDR--QSLLHGGPKGTPLWMAPEMLLGKPFDE--KADIYSF 750 LLD K++DFGLT I+ + +S + W APE+L K + AD+YSF Sbjct: 922 LLDSKWNVKVSDFGLTKIKDNNKGKSSTKEDSVCSIQWTAPEVLSEKQDIDYILADVYSF 981 Query: 751 GIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLS----YLIHRCWHPQP 918 GII+W+L+TR + AV +N RP + + +S L++ CWH Sbjct: 982 GIIMWELMTRLRPYIGLSPAAIAV-AVIRDNLRPEIQEEDINLMSSDYVELVNICWHKDT 1040 Query: 919 ALRPSFTEI 945 +RPSF EI Sbjct: 1041 MIRPSFLEI 1049
>Q7TQP6:TNI3K_RAT Serine/threonine-protein kinase TNNI3K - Rattus norvegicus (Rat)| Length = 835 Score = 129 bits (323), Expect = 5e-29 Identities = 98/314 (31%), Positives = 153/314 (48%), Gaps = 17/314 (5%) Frame = +1 Query: 55 PSKRYRCAAMQPSAGPGTGAAIHDPFGVAKGFVGLEIPAEQLIIEEEL--------SKDK 210 P + C G G+ ++ P G K + A+ L++ EL S+ + Sbjct: 407 PQEELPCNEYSQPGGDGSYVSVPSPLGKIKSMT--KEKADVLLLRAELPSRFHLQLSEIE 464 Query: 211 DGEDIGR--FGKVFKGRCFGLEVAVKIPKVQEL-SPEQLEKFKQEVAINSEINHPNVVRF 381 E IG FGKV+KGRC VA+K + S ++ F +EV+I ++NHP VV+F Sbjct: 465 FHEIIGSGSFGKVYKGRCRNKIVAIKRYRANTYCSKSDVDMFCREVSILCQLNHPCVVQF 524 Query: 382 LGACL-KPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAAN--L 552 +GACL P F +VT+ + R L L ++ IA D+ KGM Y+H+ + Sbjct: 525 VGACLDDPSQFAIVTQYISGGSLFSLLHEQKRILDLQSKLIIAVDVAKGMEYLHSLTQPI 584 Query: 553 VHLDLKPENVLLDFNGTAKIADFGLT--VIRLDRQSLLHGGPKGTPLWMAPEMLLG-KPF 723 +H DL N+LL +G A +ADFG + + LD ++ G WMAPE+ + Sbjct: 585 IHRDLNSHNILLYEDGHAVVADFGESRFLQSLDEDNMTK--QPGNLRWMAPEVFTQCTRY 642 Query: 724 DEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRC 903 KAD++S+ + LW+LLT +A ++ RPP+ + +S L+ R Sbjct: 643 TIKADVFSYSLCLWELLT-GEIPFAHLKPAAAAADMAYHHIRPPIGYSIPKPISSLLIRG 701 Query: 904 WHPQPALRPSFTEI 945 W+ P RP F+E+ Sbjct: 702 WNACPEGRPEFSEV 715
>Q62073:M3K7_MOUSE Mitogen-activated protein kinase kinase kinase 7 - Mus musculus| (Mouse) Length = 579 Score = 127 bits (318), Expect = 2e-28 Identities = 87/270 (32%), Positives = 130/270 (48%), Gaps = 7/270 (2%) Frame = +1 Query: 157 LEIPAEQLIIEEELSKDKDGEDI---GRFGKVFKGRCFGLEVAVKIPKVQELSPEQLEKF 327 +E P++ L EE K+ + E++ G FG V K + +VA+K Q S + + F Sbjct: 19 IEAPSQVLNFEEIDYKEIEVEEVVGRGAFGVVCKAKWRAKDVAIK----QIESESERKAF 74 Query: 328 KQEVAINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIA 507 E+ S +NHPN+V+ GACL P+ + + + A M Sbjct: 75 IVELRQLSRVNHPNIVKLYGACLNPVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWC 134 Query: 508 RDIVKGMIYIHAAN---LVHLDLKPENVLLDFNGTA-KIADFGLTVIRLDRQSLLHGGPK 675 +G+ Y+H+ L+H DLKP N+LL GT KI DFG D Q+ + K Sbjct: 135 LQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLKICDFGTAC---DIQTHMTNN-K 190 Query: 676 GTPLWMAPEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPP 855 G+ WMAPE+ G + EK D++S+GIILW+++TR I N RPP Sbjct: 191 GSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFRIMWAVHNGTRPP 250 Query: 856 MPQGTNQKLSYLIHRCWHPQPALRPSFTEI 945 + + + + L+ RCW P+ RPS EI Sbjct: 251 LIKNLPKPIESLMTRCWSKDPSQRPSMEEI 280
>O43318:M3K7_HUMAN Mitogen-activated protein kinase kinase kinase 7 - Homo sapiens| (Human) Length = 606 Score = 127 bits (318), Expect = 2e-28 Identities = 87/270 (32%), Positives = 130/270 (48%), Gaps = 7/270 (2%) Frame = +1 Query: 157 LEIPAEQLIIEEELSKDKDGEDI---GRFGKVFKGRCFGLEVAVKIPKVQELSPEQLEKF 327 +E P++ L EE K+ + E++ G FG V K + +VA+K Q S + + F Sbjct: 19 IEAPSQVLNFEEIDYKEIEVEEVVGRGAFGVVCKAKWRAKDVAIK----QIESESERKAF 74 Query: 328 KQEVAINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIA 507 E+ S +NHPN+V+ GACL P+ + + + A M Sbjct: 75 IVELRQLSRVNHPNIVKLYGACLNPVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWC 134 Query: 508 RDIVKGMIYIHAAN---LVHLDLKPENVLLDFNGTA-KIADFGLTVIRLDRQSLLHGGPK 675 +G+ Y+H+ L+H DLKP N+LL GT KI DFG D Q+ + K Sbjct: 135 LQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLKICDFGTAC---DIQTHMTNN-K 190 Query: 676 GTPLWMAPEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPP 855 G+ WMAPE+ G + EK D++S+GIILW+++TR I N RPP Sbjct: 191 GSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFRIMWAVHNGTRPP 250 Query: 856 MPQGTNQKLSYLIHRCWHPQPALRPSFTEI 945 + + + + L+ RCW P+ RPS EI Sbjct: 251 LIKNLPKPIESLMTRCWSKDPSQRPSMEEI 280
>Q9NYL2:MLTK_HUMAN Mitogen-activated protein kinase kinase kinase MLT - Homo sapiens| (Human) Length = 800 Score = 126 bits (317), Expect = 3e-28 Identities = 80/266 (30%), Positives = 131/266 (49%), Gaps = 4/266 (1%) Frame = +1 Query: 226 GRFGKVFKGRCFGLEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGACLKPL 405 G FG V++ + I + +E++ ++L K ++E I S ++H N+++F G L+P Sbjct: 25 GSFGSVYRAKW--------ISQDKEVAVKKLLKIEKEAEILSVLSHRNIIQFYGVILEPP 76 Query: 406 NFRLVTEXXXXXXXXXXX-SNKARPLSLARRMRIARDIVKGMIYIHA---ANLVHLDLKP 573 N+ +VTE SN++ + + M A D+ KGM Y+H ++H DLK Sbjct: 77 NYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVAKGMHYLHMEAPVKVIHRDLKS 136 Query: 574 ENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWMAPEMLLGKPFDEKADIYSFG 753 NV++ +G KI DFG + H GT WMAPE++ P E D YS+G Sbjct: 137 RNVVIAADGVLKICDFGASRFH---NHTTHMSLVGTFPWMAPEVIQSLPVSETCDTYSYG 193 Query: 754 IILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPALRPS 933 ++LW++LTR V N R +P + + L+H+CW RPS Sbjct: 194 VVLWEMLTREVPFKGLEGLQVAWLVVE-KNERLTIPSSCPRSFAELLHQCWEADAKKRPS 252 Query: 934 FTEIDNAYLQPIIVETAIPDEVGRVL 1011 F +I + L+ + +T++PD+ L Sbjct: 253 FKQI-ISILESMSNDTSLPDKCNSFL 277
>Q5GIG6:TNI3K_MOUSE Serine/threonine-protein kinase TNNI3K - Mus musculus (Mouse)| Length = 834 Score = 126 bits (316), Expect = 3e-28 Identities = 97/314 (30%), Positives = 151/314 (48%), Gaps = 17/314 (5%) Frame = +1 Query: 55 PSKRYRCAAMQPSAGPGTGAAIHDPFGVAKGFVGLEIPAEQLIIEEEL--------SKDK 210 P C G G+ ++ P G K + A+ L++ EL S+ + Sbjct: 406 PQDELPCNEYSQPGGDGSYVSVPSPLGKIKSMT--KEKADVLLLRAELPSRFHLQLSEIE 463 Query: 211 DGEDIGR--FGKVFKGRCFGLEVAVKIPKVQEL-SPEQLEKFKQEVAINSEINHPNVVRF 381 E IG FGKV+KGRC VA+K + S ++ F +EV+I ++NHP VV+F Sbjct: 464 FHEIIGSGSFGKVYKGRCRNKIVAIKRYRANTYCSKSDVDMFCREVSILCQLNHPCVVQF 523 Query: 382 LGACL-KPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAAN--L 552 +GACL P F +VT+ + R L L ++ IA D+ KGM Y+H+ + Sbjct: 524 VGACLDDPSQFAIVTQYISGGSLFSLLHEQKRILDLQSKLIIAVDVAKGMEYLHSLTQPI 583 Query: 553 VHLDLKPENVLLDFNGTAKIADFGLT--VIRLDRQSLLHGGPKGTPLWMAPEMLLG-KPF 723 +H DL N+LL +G A +ADFG + + LD ++ G WMAPE+ + Sbjct: 584 IHRDLNSHNILLYEDGHAVVADFGESRFLQSLDEDNMTK--QPGNLRWMAPEVFTQCTRY 641 Query: 724 DEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRC 903 KAD++S+ + LW+LL +A ++ RPP+ + +S L+ R Sbjct: 642 TIKADVFSYALCLWELLI-GEIPFAHLKPAAAAADMAYHHIRPPIGYSIPKPISSLLMRG 700 Query: 904 WHPQPALRPSFTEI 945 W+ P RP F+E+ Sbjct: 701 WNACPEGRPEFSEV 714
>Q9ESL4:MLTK_MOUSE Mitogen-activated protein kinase kinase kinase MLT - Mus musculus| (Mouse) Length = 802 Score = 126 bits (316), Expect = 3e-28 Identities = 80/266 (30%), Positives = 130/266 (48%), Gaps = 4/266 (1%) Frame = +1 Query: 226 GRFGKVFKGRCFGLEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGACLKPL 405 G FG V++ + I + +E++ ++L K ++E I S ++H N+++F G L+P Sbjct: 25 GSFGSVYRAKW--------ISQDKEVAVKKLLKIEKEAEILSVLSHRNIIQFYGVILEPP 76 Query: 406 NFRLVTEXXXXXXXXXXX-SNKARPLSLARRMRIARDIVKGMIYIHA---ANLVHLDLKP 573 N+ +VTE SN++ + + M A D+ KGM Y+H ++H DLK Sbjct: 77 NYGIVTEYASLGSLYDYINSNRSEEMDMEHIMTWATDVAKGMHYLHMEAPVKVIHRDLKS 136 Query: 574 ENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWMAPEMLLGKPFDEKADIYSFG 753 NV++ +G KI DFG + H GT WMAPE++ P E D YS+G Sbjct: 137 RNVVIAADGVLKICDFGASRFH---NHTTHMSLVGTFPWMAPEVIQSLPVSETCDTYSYG 193 Query: 754 IILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPALRPS 933 ++LW++LTR V N R +P + + L+H+CW RPS Sbjct: 194 VVLWEMLTREVPFKGLEGLQVAWLVVE-KNERLTIPSSCPRSFAELLHQCWEADAKKRPS 252 Query: 934 FTEIDNAYLQPIIVETAIPDEVGRVL 1011 F +I + L+ + +T +PD+ L Sbjct: 253 FKQI-ISILESMSNDTNLPDQCNSFL 277
>Q59H18:TNI3K_HUMAN Serine/threonine-protein kinase TNNI3K - Homo sapiens (Human)| Length = 936 Score = 124 bits (312), Expect = 1e-27 Identities = 95/314 (30%), Positives = 151/314 (48%), Gaps = 17/314 (5%) Frame = +1 Query: 55 PSKRYRCAAMQPSAGPGTGAAIHDPFGVAKGFVGLEIPAEQLIIEE--------ELSKDK 210 P C G G+ ++ P G K + A+ L++ +LS+ + Sbjct: 508 PQDELPCNEYSQPGGDGSYVSVPSPLGKIKSMT--KEKADILLLRAGLPSHFHLQLSEIE 565 Query: 211 DGEDIGR--FGKVFKGRCFGLEVAVKIPKVQEL-SPEQLEKFKQEVAINSEINHPNVVRF 381 E IG FGKV+KGRC VA+K + S ++ F +EV+I ++NHP V++F Sbjct: 566 FHEIIGSGSFGKVYKGRCRNKIVAIKRYRANTYCSKSDVDMFCREVSILCQLNHPCVIQF 625 Query: 382 LGACLK-PLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIH--AANL 552 +GACL P F +VT+ + R L L ++ IA D+ KGM Y+H + Sbjct: 626 VGACLNDPSQFAIVTQYISGGSLFSLLHEQKRILDLQSKLIIAVDVAKGMEYLHNLTQPI 685 Query: 553 VHLDLKPENVLLDFNGTAKIADFGLT--VIRLDRQSLLHGGPKGTPLWMAPEMLLG-KPF 723 +H DL N+LL +G A +ADFG + + LD ++ G WMAPE+ + Sbjct: 686 IHRDLNSHNILLYEDGHAVVADFGESRFLQSLDEDNMTK--QPGNLRWMAPEVFTQCTRY 743 Query: 724 DEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRC 903 KAD++S+ + LW++LT +A ++ RPP+ + +S L+ R Sbjct: 744 TIKADVFSYALCLWEILT-GEIPFAHLKPAAAAADMAYHHIRPPIGYSIPKPISSLLIRG 802 Query: 904 WHPQPALRPSFTEI 945 W+ P RP F+E+ Sbjct: 803 WNACPEGRPEFSEV 816
>P11345:RAF1_RAT RAF proto-oncogene serine/threonine-protein kinase - Rattus| norvegicus (Rat) Length = 648 Score = 124 bits (311), Expect = 1e-27 Identities = 84/260 (32%), Positives = 133/260 (51%), Gaps = 7/260 (2%) Frame = +1 Query: 19 SPPSSTCREGPLPSKRYRCAAMQPSAGPGTGAAIHD---PFGVAKGFVGLEIPAEQLIIE 189 SP + + P+P++R R PG+G + P G EI A ++++ Sbjct: 301 SPTGWSQPKTPVPAQRERA--------PGSGTQEKNKIRPRGQRDSSYYWEIEASEVMLS 352 Query: 190 EELSKDKDGEDIGRFGKVFKGRCFGLEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPN 369 + G FG V+KG+ G +VAVKI KV + +PEQL+ F+ EVA+ + H N Sbjct: 353 TRIGS-------GSFGTVYKGKWHG-DVAVKILKVVDPTPEQLQAFRNEVAVLRKTRHVN 404 Query: 370 VVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAAN 549 ++ F+G K N +VT+ + + + + IAR +GM Y+HA N Sbjct: 405 ILLFMGYMTKD-NLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKN 463 Query: 550 LVHLDLKPENVLLDFNGTAKIADFGLTVIRLD-RQSLLHGGPKGTPLWMAPEMLL---GK 717 ++H D+K N+ L T KI DFGL ++ S P G+ LWMAPE++ Sbjct: 464 IIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNN 523 Query: 718 PFDEKADIYSFGIILWQLLT 777 PF ++D+YS+GI+L++L+T Sbjct: 524 PFSFQSDVYSYGIVLYELMT 543
>Q4JIM5:ABL2_MOUSE Tyrosine-protein kinase ABL2 - Mus musculus (Mouse)| Length = 1182 Score = 124 bits (310), Expect = 2e-27 Identities = 81/265 (30%), Positives = 127/265 (47%), Gaps = 3/265 (1%) Frame = +1 Query: 226 GRFGKVFKG--RCFGLEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGACLK 399 G++G+V+ G + + L VAVK K + ++E+F +E A+ EI HPN+V+ LG C Sbjct: 297 GQYGEVYVGVWKKYSLTVAVKTFKEDTM---EVEEFLKEAAVMKEIKHPNLVQLLGVCTL 353 Query: 400 PLNFRLVTEXXXXXXXXXXXSNKARP-LSLARRMRIARDIVKGMIYIHAANLVHLDLKPE 576 F +VTE +R ++ + +A I M Y+ N +H DL Sbjct: 354 EPPFYIVTEYMPYGNLLDYLRECSREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAAR 413 Query: 577 NVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWMAPEMLLGKPFDEKADIYSFGI 756 N L+ N K+ADFGL+ + H G K W APE L F K+D+++FG+ Sbjct: 414 NCLVGENHVVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGV 473 Query: 757 ILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPALRPSF 936 +LW++ T + + YR P+G K+ L+ CW PA RPSF Sbjct: 474 LLWEIAT-YGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWKWSPADRPSF 532 Query: 937 TEIDNAYLQPIIVETAIPDEVGRVL 1011 E A+ + + +++I +EV L Sbjct: 533 AETHQAF-ETMFHDSSISEEVAEEL 556
>Q60700:M3K12_MOUSE Mitogen-activated protein kinase kinase kinase 12 - Mus musculus| (Mouse) Length = 888 Score = 123 bits (309), Expect = 2e-27 Identities = 79/262 (30%), Positives = 127/262 (48%) Frame = +1 Query: 160 EIPAEQLIIEEELSKDKDGEDIGRFGKVFKGRCFGLEVAVKIPKVQELSPEQLEKFKQEV 339 E+P E+++ D G G VF GR G EVAVK KV++L ++ ++ Sbjct: 152 EVPFEEIL-------DLQWVGSGAQGAVFLGRFHGEEVAVK--KVRDLKETDIKHLRK-- 200 Query: 340 AINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIV 519 + HPN++ F G C + + ++ E RP++ + + + I Sbjct: 201 -----LKHPNIITFKGVCTQAPCYCILMEFCAQGQLYEVL-RAGRPVTPSLLVDWSMGIA 254 Query: 520 KGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWMAP 699 GM Y+H ++H DLK N+L+ ++ KI+DFG + D+ + + GT WMAP Sbjct: 255 GGMNYLHLHKIIHRDLKSPNMLITYDDVVKISDFGTSKELSDKSTKMSFA--GTVAWMAP 312 Query: 700 EMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQK 879 E++ +P EK DI+SFG++LW+LLT I V N+ P+P Sbjct: 313 EVIRNEPVSEKVDIWSFGVVLWELLT-GEIPYKDVDSSAIIWGVGSNSLHLPVPSSCPDG 371 Query: 880 LSYLIHRCWHPQPALRPSFTEI 945 L+ +CW+ +P RPSF +I Sbjct: 372 FKILLRQCWNSKPRNRPSFRQI 393
>Q12852:M3K12_HUMAN Mitogen-activated protein kinase kinase kinase 12 - Homo sapiens| (Human) Length = 859 Score = 123 bits (309), Expect = 2e-27 Identities = 79/262 (30%), Positives = 127/262 (48%) Frame = +1 Query: 160 EIPAEQLIIEEELSKDKDGEDIGRFGKVFKGRCFGLEVAVKIPKVQELSPEQLEKFKQEV 339 E+P E+++ D G G VF GR G EVAVK KV++L ++ ++ Sbjct: 119 EVPFEEIL-------DLQWVGSGAQGAVFLGRFHGEEVAVK--KVRDLKETDIKHLRK-- 167 Query: 340 AINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIV 519 + HPN++ F G C + + ++ E RP++ + + + I Sbjct: 168 -----LKHPNIITFKGVCTQAPCYCILMEFCAQGQLYEVL-RAGRPVTPSLLVDWSMGIA 221 Query: 520 KGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWMAP 699 GM Y+H ++H DLK N+L+ ++ KI+DFG + D+ + + GT WMAP Sbjct: 222 GGMNYLHLHKIIHRDLKSPNMLITYDDVVKISDFGTSKELSDKSTKMSFA--GTVAWMAP 279 Query: 700 EMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQK 879 E++ +P EK DI+SFG++LW+LLT I V N+ P+P Sbjct: 280 EVIRNEPVSEKVDIWSFGVVLWELLT-GEIPYKDVDSSAIIWGVGSNSLHLPVPSSCPDG 338 Query: 880 LSYLIHRCWHPQPALRPSFTEI 945 L+ +CW+ +P RPSF +I Sbjct: 339 FKILLRQCWNSKPRNRPSFRQI 360
>Q63796:M3K12_RAT Mitogen-activated protein kinase kinase kinase 12 - Rattus| norvegicus (Rat) Length = 888 Score = 123 bits (308), Expect = 3e-27 Identities = 79/262 (30%), Positives = 127/262 (48%) Frame = +1 Query: 160 EIPAEQLIIEEELSKDKDGEDIGRFGKVFKGRCFGLEVAVKIPKVQELSPEQLEKFKQEV 339 E+P E+++ D G G VF GR G EVAVK KV++L ++ ++ Sbjct: 152 EVPFEEIL-------DLQWVGSGAQGAVFLGRFHGEEVAVK--KVRDLKETDIKHLRK-- 200 Query: 340 AINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIV 519 + HPN++ F G C + + ++ E RP++ + + + I Sbjct: 201 -----LKHPNIITFKGVCTQAPCYCILMEFCAQGQLYEVL-RAGRPVTPSLLVDWSMGIA 254 Query: 520 KGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWMAP 699 GM Y+H ++H DLK N+L+ ++ KI+DFG + D+ + + GT WMAP Sbjct: 255 GGMNYLHLHKIIHRDLKSPNMLITYDDVVKISDFGTSKELSDKSTKMSFA--GTVAWMAP 312 Query: 700 EMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQK 879 E++ +P EK DI+SFG++LW+LLT I V N+ P+P Sbjct: 313 EVIRNEPVSEKVDIWSFGVVLWELLT-GEIPYKDVDSSAIIWGVGSNSLHLPVPSSCPDG 371 Query: 880 LSYLIHRCWHPQPALRPSFTEI 945 L+ +CW+ +P RPSF +I Sbjct: 372 FKILLRQCWNRKPRNRPSFRQI 393
>P42684:ABL2_HUMAN Tyrosine-protein kinase ABL2 - Homo sapiens (Human)| Length = 1182 Score = 123 bits (308), Expect = 3e-27 Identities = 81/265 (30%), Positives = 126/265 (47%), Gaps = 3/265 (1%) Frame = +1 Query: 226 GRFGKVFKG--RCFGLEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGACLK 399 G++G+V+ G + + L VAVK K + ++E+F +E A+ EI HPN+V+ LG C Sbjct: 297 GQYGEVYVGVWKKYSLTVAVKTLKEDTM---EVEEFLKEAAVMKEIKHPNLVQLLGVCTL 353 Query: 400 PLNFRLVTEXXXXXXXXXXXSNKARP-LSLARRMRIARDIVKGMIYIHAANLVHLDLKPE 576 F +VTE R ++ + +A I M Y+ N +H DL Sbjct: 354 EPPFYIVTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAAR 413 Query: 577 NVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWMAPEMLLGKPFDEKADIYSFGI 756 N L+ N K+ADFGL+ + H G K W APE L F K+D+++FG+ Sbjct: 414 NCLVGENHVVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGV 473 Query: 757 ILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPALRPSF 936 +LW++ T + + YR P+G K+ L+ CW PA RPSF Sbjct: 474 LLWEIAT-YGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWKWSPADRPSF 532 Query: 937 TEIDNAYLQPIIVETAIPDEVGRVL 1011 E A+ + + +++I +EV L Sbjct: 533 AETHQAF-ETMFHDSSISEEVAEEL 556
>Q99N57:RAF1_MOUSE RAF proto-oncogene serine/threonine-protein kinase - Mus musculus| (Mouse) Length = 648 Score = 122 bits (305), Expect = 7e-27 Identities = 83/259 (32%), Positives = 132/259 (50%), Gaps = 7/259 (2%) Frame = +1 Query: 19 SPPSSTCREGPLPSKRYRCAAMQPSAGPGTGAAIHD---PFGVAKGFVGLEIPAEQLIIE 189 SP + + P+P++R R PG+G + P G EI A ++++ Sbjct: 301 SPTGWSQPKTPVPAQRERA--------PGSGTQEKNKIRPRGQRDSSYYWEIEASEVMLS 352 Query: 190 EELSKDKDGEDIGRFGKVFKGRCFGLEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPN 369 + G FG V+KG+ G +VAVKI KV + +PEQL+ F+ EVA+ + H N Sbjct: 353 TRIGS-------GSFGTVYKGKWHG-DVAVKILKVVDPTPEQLQAFRNEVAVLRKTRHVN 404 Query: 370 VVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAAN 549 ++ F+G K N +VT+ + + + + IAR +GM Y+HA N Sbjct: 405 ILLFMGYMTKD-NLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKN 463 Query: 550 LVHLDLKPENVLLDFNGTAKIADFGLTVIRLD-RQSLLHGGPKGTPLWMAPEMLL---GK 717 ++H D+K N+ L T KI DFGL ++ S P G+ LWMAPE++ Sbjct: 464 IIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDDN 523 Query: 718 PFDEKADIYSFGIILWQLL 774 PF ++D+YS+GI+L++L+ Sbjct: 524 PFSFQSDVYSYGIVLYELM 542
>P00531:MIL_AVIMH Serine/threonine-protein kinase-transforming protein mil - Avian| retrovirus MH2 Length = 380 Score = 122 bits (305), Expect = 7e-27 Identities = 83/260 (31%), Positives = 131/260 (50%), Gaps = 7/260 (2%) Frame = +1 Query: 19 SPPSSTCREGPLPSKRYRCAAMQPSAGPGTGAAIHD---PFGVAKGFVGLEIPAEQLIIE 189 SP + + P+P++R R PGT + P G EI A ++++ Sbjct: 34 SPTGWSQPKTPVPAQRERA--------PGTNTQEKNKIRPRGQRDSSYYWEIEASEVLLS 85 Query: 190 EELSKDKDGEDIGRFGKVFKGRCFGLEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPN 369 + G FG V+KG+ G +VAVKI KV + +PEQ + F+ EVA+ + H N Sbjct: 86 TRIGS-------GSFGTVYKGKWHG-DVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVN 137 Query: 370 VVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAAN 549 ++ F+G K N +VT+ + + + + IAR +GM Y+HA N Sbjct: 138 ILLFMGYMTKD-NLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKN 196 Query: 550 LVHLDLKPENVLLDFNGTAKIADFGLTVIRLD-RQSLLHGGPKGTPLWMAPEMLL---GK 717 ++H D+K N+ L T KI DFGL ++ S P G+ LWMAPE++ Sbjct: 197 IIHRDMKSNNIFLHGGLTVKIGDFGLATVKSRWSGSQQVEQPTGSILWMAPEVIRMQDSN 256 Query: 718 PFDEKADIYSFGIILWQLLT 777 PF ++D+YS+GI+L++L+T Sbjct: 257 PFSFQSDVYSYGIVLYELMT 276
>Q5R5M7:RAF1_PONPY RAF proto-oncogene serine/threonine-protein kinase - Pongo pygmaeus| (Orangutan) Length = 648 Score = 121 bits (304), Expect = 9e-27 Identities = 83/257 (32%), Positives = 131/257 (50%), Gaps = 4/257 (1%) Frame = +1 Query: 19 SPPSSTCREGPLPSKRYRCAAMQPSAGPGTGAAIHDPFGVAKGFVGLEIPAEQLIIEEEL 198 SP + + P+P++R R P +G I P G EI A ++++ + Sbjct: 301 SPTGWSQPKTPVPAQRERA----PVSGTQEKNKIR-PRGQRDSSYYWEIEASEVMLSTRI 355 Query: 199 SKDKDGEDIGRFGKVFKGRCFGLEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVR 378 G FG V+KG+ G +VAVKI KV + +PEQ + F+ EVA+ + H N++ Sbjct: 356 GS-------GSFGTVYKGKWHG-DVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILL 407 Query: 379 FLGACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVH 558 F+G K N +VT+ + + + + IAR +GM Y+HA N++H Sbjct: 408 FMGYMTKD-NLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIH 466 Query: 559 LDLKPENVLLDFNGTAKIADFGLTVIRLD-RQSLLHGGPKGTPLWMAPEMLL---GKPFD 726 D+K N+ L T KI DFGL ++ S P G+ LWMAPE++ PF Sbjct: 467 RDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFS 526 Query: 727 EKADIYSFGIILWQLLT 777 ++D+YS+GI+L++L+T Sbjct: 527 FQSDVYSYGIVLYELMT 543
>P04049:RAF1_HUMAN RAF proto-oncogene serine/threonine-protein kinase - Homo sapiens| (Human) Length = 648 Score = 121 bits (304), Expect = 9e-27 Identities = 83/257 (32%), Positives = 131/257 (50%), Gaps = 4/257 (1%) Frame = +1 Query: 19 SPPSSTCREGPLPSKRYRCAAMQPSAGPGTGAAIHDPFGVAKGFVGLEIPAEQLIIEEEL 198 SP + + P+P++R R P +G I P G EI A ++++ + Sbjct: 301 SPTGWSQPKTPVPAQRERA----PVSGTQEKNKIR-PRGQRDSSYYWEIEASEVMLSTRI 355 Query: 199 SKDKDGEDIGRFGKVFKGRCFGLEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVR 378 G FG V+KG+ G +VAVKI KV + +PEQ + F+ EVA+ + H N++ Sbjct: 356 GS-------GSFGTVYKGKWHG-DVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILL 407 Query: 379 FLGACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVH 558 F+G K N +VT+ + + + + IAR +GM Y+HA N++H Sbjct: 408 FMGYMTKD-NLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIH 466 Query: 559 LDLKPENVLLDFNGTAKIADFGLTVIRLD-RQSLLHGGPKGTPLWMAPEMLL---GKPFD 726 D+K N+ L T KI DFGL ++ S P G+ LWMAPE++ PF Sbjct: 467 RDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFS 526 Query: 727 EKADIYSFGIILWQLLT 777 ++D+YS+GI+L++L+T Sbjct: 527 FQSDVYSYGIVLYELMT 543
>P05625:RAF1_CHICK RAF proto-oncogene serine/threonine-protein kinase - Gallus gallus| (Chicken) Length = 647 Score = 121 bits (304), Expect = 9e-27 Identities = 83/260 (31%), Positives = 131/260 (50%), Gaps = 7/260 (2%) Frame = +1 Query: 19 SPPSSTCREGPLPSKRYRCAAMQPSAGPGTGAAIHD---PFGVAKGFVGLEIPAEQLIIE 189 SP + + P+P++R R PGT + P G EI A ++++ Sbjct: 301 SPTGWSQPKTPVPAQRERA--------PGTNTQEKNKIRPRGQRDSSYYWEIEASEVMLS 352 Query: 190 EELSKDKDGEDIGRFGKVFKGRCFGLEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPN 369 + G FG V+KG+ G +VAVKI KV + +PEQ + F+ EVA+ + H N Sbjct: 353 TRIGS-------GSFGTVYKGKWHG-DVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVN 404 Query: 370 VVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAAN 549 ++ F+G K N +VT+ + + + + IAR +GM Y+HA N Sbjct: 405 ILLFMGYMTKD-NLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKN 463 Query: 550 LVHLDLKPENVLLDFNGTAKIADFGLTVIRLD-RQSLLHGGPKGTPLWMAPEMLL---GK 717 ++H D+K N+ L T KI DFGL ++ S P G+ LWMAPE++ Sbjct: 464 IIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSILWMAPEVIRMQDSN 523 Query: 718 PFDEKADIYSFGIILWQLLT 777 PF ++D+YS+GI+L++L+T Sbjct: 524 PFSFQSDVYSYGIVLYELMT 543
>P10447:ABL_FSVHY Tyrosine-protein kinase transforming protein Abl - Feline sarcoma| virus (strain Hardy-Zuckerman 2) Length = 439 Score = 121 bits (304), Expect = 9e-27 Identities = 74/243 (30%), Positives = 119/243 (48%), Gaps = 3/243 (1%) Frame = +1 Query: 226 GRFGKVFKG--RCFGLEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGACLK 399 G++G+V++G + + L VAVK K + ++E+F +E A+ EI HPN+V+ LG C + Sbjct: 200 GQYGEVYEGVWKKYSLTVAVKTLKEDTM---EVEEFLKEAAVMKEIKHPNLVQLLGVCTR 256 Query: 400 PLNFRLVTEXXXXXXXXXXXSNKARP-LSLARRMRIARDIVKGMIYIHAANLVHLDLKPE 576 F ++TE R ++ + +A I M Y+ N +H DL Sbjct: 257 EPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAAR 316 Query: 577 NVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWMAPEMLLGKPFDEKADIYSFGI 756 N L+ N K+ADFGL+ + H G K W APE L F K+D+++FG+ Sbjct: 317 NCLVGENHLVKVADFGLSRLMTGDTYTAHAGTKFPIKWTAPESLAYNKFSIKSDVWAFGV 376 Query: 757 ILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPALRPSF 936 +LW++ T + + +YR P+G +K+ L+ CW P+ RP+F Sbjct: 377 LLWEIAT-YGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPAF 435 Query: 937 TEI 945 EI Sbjct: 436 AEI 438
>P80192:M3K9_HUMAN Mitogen-activated protein kinase kinase kinase 9 - Homo sapiens| (Human) Length = 1104 Score = 120 bits (302), Expect = 1e-26 Identities = 88/276 (31%), Positives = 127/276 (46%), Gaps = 13/276 (4%) Frame = +1 Query: 157 LEIPAEQLIIEEELSKDKDGEDIGRFGKVFKGRCFGLEVAVKIPK--VQELSPEQLEKFK 330 LEI +L +EE + IG FGKV++ G EVAVK + E + +E + Sbjct: 137 LEIDFAELTLEEIIG-------IGGFGKVYRAFWIGDEVAVKAARHDPDEDISQTIENVR 189 Query: 331 QEVAINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIAR 510 QE + + + HPN++ G CLK N LV E S K P + + A Sbjct: 190 QEAKLFAMLKHPNIIALRGVCLKEPNLCLVMEFARGGPLNRVLSGKRIPPDIL--VNWAV 247 Query: 511 DIVKGMIYIH---AANLVHLDLKPENVLL-------DF-NGTAKIADFGLTVIRLDRQSL 657 I +GM Y+H ++H DLK N+L+ D N KI DFGL + Sbjct: 248 QIARGMNYLHDEAIVPIIHRDLKSSNILILQKVENGDLSNKILKITDFGLA---REWHRT 304 Query: 658 LHGGPKGTPLWMAPEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAI 837 GT WMAPE++ F + +D++S+G++LW+LLT VA+ Sbjct: 305 TKMSAAGTYAWMAPEVIRASMFSKGSDVWSYGVLLWELLT-GEVPFRGIDGLAVAYGVAM 363 Query: 838 NNYRPPMPQGTNQKLSYLIHRCWHPQPALRPSFTEI 945 N P+P + + L+ CW+P P RPSFT I Sbjct: 364 NKLALPIPSTCPEPFAKLMEDCWNPDPHSRPSFTNI 399
>P18161:KYK2_DICDI Tyrosine-protein kinase 2 - Dictyostelium discoideum (Slime mold)| Length = 410 Score = 120 bits (302), Expect = 1e-26 Identities = 78/248 (31%), Positives = 123/248 (49%), Gaps = 6/248 (2%) Frame = +1 Query: 226 GRFGKVFKGRCFGLEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGACLKPL 405 G F +V++G G+ VA+K K+ + E+F +EV + NH N+V F+GAC KP Sbjct: 117 GAFSEVWEGWWKGIHVAIKKLKIIGDEEQFKERFIREVQNLKKGNHQNIVMFIGACYKPA 176 Query: 406 NFRLVTEXXXXXXXXXXXSNKARP---LSLARRMRIARDIVKGMIYIHAANLVHLDLKPE 576 N + P S +++A D+ G++++H+ +VH DL + Sbjct: 177 CIITEYMAGGSLYNILHNPNSSTPKVKYSFPLVLKMATDMALGLLHLHSITIVHRDLTSQ 236 Query: 577 NVLLDFNGTAKIADFGLTVIRLDRQSL-LHGGPKGTPLWMAPEML--LGKPFDEKADIYS 747 N+LLD G KI+DFGL+ + S+ + G P W PE+ LG + EK D+Y Sbjct: 237 NILLDELGNIKISDFGLSAEKSREGSMTMTNGGICNPRWRPPELTKNLGH-YSEKVDVYC 295 Query: 748 FGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPALR 927 F +++W++LT + VA RPP+P+ + +L L+ +CW P R Sbjct: 296 FSLVVWEILTGEIPFSDLDGSQRSAQ-VAYAGLRPPIPEYCDPELKLLLTQCWEADPNDR 354 Query: 928 PSFTEIDN 951 P FT I N Sbjct: 355 PPFTYIVN 362
>P18106:FPS_DROME Tyrosine-protein kinase Fps85D - Drosophila melanogaster (Fruit fly)| Length = 1325 Score = 120 bits (302), Expect = 1e-26 Identities = 73/245 (29%), Positives = 122/245 (49%), Gaps = 3/245 (1%) Frame = +1 Query: 226 GRFGKVFKGRCFG--LEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGACLK 399 G FG V+K + L+VAVK ++ L EQ KF QE I + +HPN+V+ +G C++ Sbjct: 1072 GNFGDVYKAKLKSTKLDVAVKTCRMT-LPDEQKRKFLQEGRILKQYDHPNIVKLIGICVQ 1130 Query: 400 PLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDLKPEN 579 +V E + L+ ++M + RD GM Y+ + N +H DL N Sbjct: 1131 KQPIMIVMELVLGGSLLTYLRKNSNGLTTRQQMGMCRDAAAGMRYLESKNCIHRDLAARN 1190 Query: 580 VLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPL-WMAPEMLLGKPFDEKADIYSFGI 756 L+D + KI+DFG++ R + + ++ G K P+ W APE L + D++S+GI Sbjct: 1191 CLVDLEHSVKISDFGMS--REEEEYIVSDGMKQIPVKWTAPEALNFGKYTSLCDVWSYGI 1248 Query: 757 ILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPALRPSF 936 ++W++ ++ + + YR P P+ T +++ L+ +CW RP F Sbjct: 1249 LMWEIFSKGDTPYSGMTNSRARERID-TGYRMPTPKSTPEEMYRLMLQCWAADAESRPHF 1307 Query: 937 TEIDN 951 EI N Sbjct: 1308 DEIYN 1312
>P18160:KYK1_DICDI Non-receptor tyrosine kinase spore lysis A - Dictyostelium discoideum| (Slime mold) Length = 1584 Score = 119 bits (299), Expect = 3e-26 Identities = 93/286 (32%), Positives = 142/286 (49%), Gaps = 26/286 (9%) Frame = +1 Query: 166 PAEQLIIEEELSKDKD----GEDIGR--FGKVFKGRCFGLEVAVKIP-KVQELSPEQLEK 324 P QL + E D + G+ IG+ FG+V +G +VA+KI + Q + L Sbjct: 1272 PPPQLPVRSEYEIDFNELEFGQTIGKGFFGEVKRGYWRETDVAIKIIYRDQFKTKSSLVM 1331 Query: 325 FKQEVAINSEINHPNVVRFLGACLK--PLNFRLVTEXXXXXXXXXXXSNKARPLSLAR-- 492 F+ EV I S++ HPNVV+FLGAC + +VTE ++ L Sbjct: 1332 FQNEVGILSKLRHPNVVQFLGACTAGGEDHHCIVTEWMGGGSLRQFLTDHFNLLEQNPHI 1391 Query: 493 RMRIARDIVKGMIYIHAAN--LVHLDLKPENVLLDFNGT-------------AKIADFGL 627 R+++A DI KGM Y+H ++H DL N+LLD N KI+DFGL Sbjct: 1392 RLKLALDIAKGMNYLHGWTPPILHRDLSSRNILLDHNIDPKNPVVSSRQDIKCKISDFGL 1451 Query: 628 TVIRLDRQSLLHGGPKGTPLWMAPEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXX 807 + ++ ++ S + P +MAPE+ G EK+D+YS+G++L++LLT Sbjct: 1452 SRLKKEQASQMTQSVGCIP-YMAPEVFKGDSNSEKSDVYSYGMVLFELLTSDEPQQDMKP 1510 Query: 808 XXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPALRPSFTEI 945 A A +YRPP+P T+ K ++ +CW P RP+F +I Sbjct: 1511 MKMAHLA-AYESYRPPIPLTTSSKWKEILTQCWDSNPDSRPTFKQI 1555
>P00522:ABL_DROME Tyrosine-protein kinase Abl - Drosophila melanogaster (Fruit fly)| Length = 1620 Score = 119 bits (299), Expect = 3e-26 Identities = 79/268 (29%), Positives = 127/268 (47%), Gaps = 3/268 (1%) Frame = +1 Query: 226 GRFGKVFKG--RCFGLEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGACLK 399 G++G+V++ + +G VAVK K ++ L+ F +E AI E+ HPN+V+ +G C + Sbjct: 380 GQYGEVYEAVWKRYGNTVAVKTLKEDTMA---LKDFLEEAAIMKEMKHPNLVQLIGVCTR 436 Query: 400 PLNFRLVTEXXXXXXXXXXXSNKARP-LSLARRMRIARDIVKGMIYIHAANLVHLDLKPE 576 F ++TE + R L + +A I GM Y+ + N +H DL Sbjct: 437 EPPFYIITEFMSHGNLLDFLRSAGRETLDAVALLYMATQIASGMSYLESRNYIHRDLAAR 496 Query: 577 NVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWMAPEMLLGKPFDEKADIYSFGI 756 N L+ N K+ADFGL + D H G K W APE L F K+D+++FG+ Sbjct: 497 NCLVGDNKLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAYNKFSTKSDVWAFGV 556 Query: 757 ILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPALRPSF 936 +LW++ T + YR P G ++ L+ +CW RP+F Sbjct: 557 LLWEIATYGMSPYPAIDLTDVYHKLD-KGYRMERPPGCPPEVYDLMRQCWQWDATDRPTF 615 Query: 937 TEIDNAYLQPIIVETAIPDEVGRVLWKN 1020 I +A L+ + E++I + V + L N Sbjct: 616 KSIHHA-LEHMFQESSITEAVEKQLNAN 642
>P00532:RAF_MSV36 Serine/threonine-protein kinase-transforming protein raf - Murine| sarcoma virus 3611 Length = 323 Score = 118 bits (296), Expect = 7e-26 Identities = 69/187 (36%), Positives = 106/187 (56%), Gaps = 4/187 (2%) Frame = +1 Query: 226 GRFGKVFKGRCFGLEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGACLKPL 405 G FG V+KG+ G +VAVKI KV + +PEQL+ F+ EVA+ + H N++ F+G K Sbjct: 33 GSFGTVYKGKWHG-DVAVKILKVVDPTPEQLQAFRNEVAVLRKTRHVNILLFMGYMTKD- 90 Query: 406 NFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDLKPENVL 585 N +VT+ + + + + IAR +GM Y+HA N++H D+K N+ Sbjct: 91 NLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIF 150 Query: 586 LDFNGTAKIADFGLTVIRLD-RQSLLHGGPKGTPLWMAPEMLL---GKPFDEKADIYSFG 753 L T KI DFGL ++ S P G+ LWMAPE++ PF ++D+YS+G Sbjct: 151 LHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDDNPFSFQSDVYSYG 210 Query: 754 IILWQLL 774 I+L++L+ Sbjct: 211 IVLYELM 217
>Q3U1V8:M3K9_MOUSE Mitogen-activated protein kinase kinase kinase 9 - Mus musculus| (Mouse) Length = 1077 Score = 118 bits (296), Expect = 7e-26 Identities = 87/276 (31%), Positives = 127/276 (46%), Gaps = 13/276 (4%) Frame = +1 Query: 157 LEIPAEQLIIEEELSKDKDGEDIGRFGKVFKGRCFGLEVAVKIPK--VQELSPEQLEKFK 330 LEI +L +EE + IG FGKV++ G EVAVK + E + +E + Sbjct: 130 LEIDFAELTLEEIIG-------IGGFGKVYRAFWAGDEVAVKAARHDPDEDISQTIENVR 182 Query: 331 QEVAINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIAR 510 QE + + + HPN++ G CLK N LV E S K P + + A Sbjct: 183 QEAKLFAMLKHPNIIALRGVCLKEPNLCLVMEFARGGPLNRVLSGKRIPPDIL--VNWAV 240 Query: 511 DIVKGMIYIH---AANLVHLDLKPENVLL-------DF-NGTAKIADFGLTVIRLDRQSL 657 I +GM Y+H ++H DLK N+L+ D N +I DFGL + Sbjct: 241 QIARGMNYLHDEAIVPIIHRDLKSSNILILQKVENGDLSNKILEITDFGLA---REWHRT 297 Query: 658 LHGGPKGTPLWMAPEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAI 837 GT WMAPE++ F + +D++S+G++LW+LLT VA+ Sbjct: 298 TKMSAAGTYAWMAPEVIRASMFSKGSDVWSYGVLLWELLT-GEVPFRGIDGLAVAYGVAM 356 Query: 838 NNYRPPMPQGTNQKLSYLIHRCWHPQPALRPSFTEI 945 N P+P + + L+ CW+P P RPSFT I Sbjct: 357 NKLALPIPSTCPEPFAKLMEDCWNPDPHSRPSFTSI 392
>P03949:ABL1_CAEEL Tyrosine-protein kinase abl-1 - Caenorhabditis elegans| Length = 1224 Score = 118 bits (295), Expect = 9e-26 Identities = 78/276 (28%), Positives = 131/276 (47%), Gaps = 4/276 (1%) Frame = +1 Query: 226 GRFGKVFKGRCFGLEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGACLKPL 405 G++G V++G + + + ++E L +F E AI +++H N+VR LG C Sbjct: 320 GQYGDVYEGYWKRHDCTIAVKALKE-DAMPLHEFLAEAAIMKDLHHKNLVRLLGVCTHEA 378 Query: 406 NFRLVTEXXXXXXXXXXXSNKAR----PLSLARRMRIARDIVKGMIYIHAANLVHLDLKP 573 F ++TE + P+ L +++A I GM Y+ A + +H DL Sbjct: 379 PFYIITEFMCNGNLLEYLRRTDKSLLPPIIL---VQMASQIASGMSYLEARHFIHRDLAA 435 Query: 574 ENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWMAPEMLLGKPFDEKADIYSFG 753 N L+ + KIADFGL + H G K W APE L F K+D+++FG Sbjct: 436 RNCLVSEHNIVKIADFGLARFMKEDTYTAHAGAKFPIKWTAPEGLAFNTFSSKSDVWAFG 495 Query: 754 IILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPALRPS 933 ++LW++ T + + N +R PQG + L+ +CW+ P+ RP Sbjct: 496 VLLWEIAT-YGMAPYPGVELSNVYGLLENGFRMDGPQGCPPSVYRLMLQCWNWSPSDRPR 554 Query: 934 FTEIDNAYLQPIIVETAIPDEVGRVLWKNHFLNLDA 1041 F +I + L+ +I ++ DEV + L KN+ L++ Sbjct: 555 FRDI-HFNLENLISSNSLNDEVQKQLKKNNDKKLES 589
>P97504:BMX_MOUSE Cytoplasmic tyrosine-protein kinase BMX - Mus musculus (Mouse)| Length = 651 Score = 117 bits (294), Expect = 1e-25 Identities = 76/282 (26%), Positives = 138/282 (48%), Gaps = 1/282 (0%) Frame = +1 Query: 127 PFGVAKGFVGLEIPAEQLIIEEELSKDKDGEDIGRFGKVFKGRCFG-LEVAVKIPKVQEL 303 P VA G E+ E++ + +EL G+FG V G+ G +VAVK+ K + Sbjct: 376 PVSVALGSGIWELKREEITLLKELGN-------GQFGVVQLGQWKGQYDVAVKMIKEGAM 428 Query: 304 SPEQLEKFKQEVAINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNKARPLS 483 S ++ F QE +++HP +V+F G C K +VTE + + L Sbjct: 429 SEDE---FFQEAQTMMKLSHPKLVKFYGVCSKKYPIYIVTEYITNGCLLNYLKSHGKGLE 485 Query: 484 LARRMRIARDIVKGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLH 663 + + + D+ +GM ++ + +H DL N L+D + + K++DFG+T LD Q + Sbjct: 486 SCQLLEMCYDVCEGMAFLESHQFIHRDLAARNCLVDSDLSVKVSDFGMTRYVLDDQYVSS 545 Query: 664 GGPKGTPLWMAPEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINN 843 G K W APE+ + K+D+++FGI++W++ + + V+ Sbjct: 546 VGTKFPVKWSAPEVFHYFKYSSKSDVWAFGILMWEVFSLGKQPYDLYDNSEVVVKVS-QG 604 Query: 844 YRPPMPQGTNQKLSYLIHRCWHPQPALRPSFTEIDNAYLQPI 969 +R PQ + + +++ CWH P RP+F ++ +A ++P+ Sbjct: 605 HRLYRPQLASDTIYQIMYSCWHELPEKRPTFQQLLSA-IEPL 645 Score = 35.4 bits (80), Expect = 0.81 Identities = 30/99 (30%), Positives = 48/99 (48%), Gaps = 4/99 (4%) Frame = +1 Query: 1390 ERMANILPRPWFYGDLDKDAAFELLRNK-QPGTFLVRFSSNPEHVG---FVISVVDHKNT 1557 E N+ WF G++ + + +LLR K + G F+VR SS F +V D K T Sbjct: 262 EEEENLHAYDWFAGNISRSQSEQLLRQKGKEGAFMVRNSSQMGMYTVSLFSKAVNDKKGT 321 Query: 1558 VVHIRVKHNAGSERPFMLLGDSTNASYSSLEEVILKNKH 1674 V H V NA ++ L + N + S+ ++I ++H Sbjct: 322 VKHYHVHTNAENK-----LYLAENYCFDSIPKLIHYHQH 355
>P09560:RAF1_XENLA RAF proto-oncogene serine/threonine-protein kinase - Xenopus laevis| (African clawed frog) Length = 638 Score = 116 bits (291), Expect = 3e-25 Identities = 72/205 (35%), Positives = 112/205 (54%), Gaps = 4/205 (1%) Frame = +1 Query: 175 QLIIEEELSKDKDGEDIGRFGKVFKGRCFGLEVAVKIPKVQELSPEQLEKFKQEVAINSE 354 ++I E + + G G FG V+KG+ G +VAVKI KV + +PEQL+ F+ EVA+ + Sbjct: 334 EIIASEVMLSSRIGS--GSFGTVYKGKWHG-DVAVKILKVTDPTPEQLQAFRNEVAVLRK 390 Query: 355 INHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIY 534 H N++ F+G K N +VT+ + + + IAR +GM Y Sbjct: 391 TRHVNILLFMGYMTKD-NLAIVTQWCEGSSLYYHLHVLDTKFQMFQLIDIARQTAQGMDY 449 Query: 535 IHAANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLD-RQSLLHGGPKGTPLWMAPEMLL 711 +HA N++H D+K N+ L T KI DFGL ++ S G+ LWMAPE++ Sbjct: 450 LHAKNIIHRDMKSNNIFLHEGLTVKIGDFGLATVKTRWSGSQQVEQLTGSILWMAPEVIR 509 Query: 712 ---GKPFDEKADIYSFGIILWQLLT 777 PF ++D+YS+GI+L++L+T Sbjct: 510 MQDNNPFSFQSDVYSYGIVLYELMT 534
>P00541:FPS_AVISP Tyrosine-protein kinase transforming protein Fps - Avian sarcoma| virus (strain PRCII) Length = 533 Score = 116 bits (291), Expect = 3e-25 Identities = 75/245 (30%), Positives = 114/245 (46%), Gaps = 4/245 (1%) Frame = +1 Query: 214 GEDIGR--FGKVFKGRCFGLEVAVKIPKVQELSPEQLE-KFKQEVAINSEINHPNVVRFL 384 GE IGR FG+VF GR V + +E P +L+ KF QE I + NHPN+VR + Sbjct: 275 GERIGRGNFGEVFSGRLRADNTPVAVKSCRETLPPELKAKFLQEARILKQYNHPNIVRLI 334 Query: 385 GACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLD 564 G C + +V E +K L + +++ + GM Y+ + + +H D Sbjct: 335 GVCTQKQPIYIVMELVQGGDFLSFLRSKGPHLKMKELIKMMENAAAGMEYLESKHCIHRD 394 Query: 565 LKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPL-WMAPEMLLGKPFDEKADI 741 L N L+ T KI+DFG++ D GG K P+ W APE L + ++D+ Sbjct: 395 LAARNCLVTEKNTLKISDFGMSRQEEDGVYASTGGMKQIPVKWTAPEALNYGRYSSESDV 454 Query: 742 YSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPA 921 +SFGI+LW+ + +A+ R P+ + + L+ RCW P Sbjct: 455 WSFGILLWEAFSLGAVPYANLSNQQTREAIE-QGVRLEPPEQCPEDVYRLMQRCWEYDPR 513 Query: 922 LRPSF 936 RPSF Sbjct: 514 RRPSF 518
>P42690:SRK4_SPOLA Tyrosine-protein kinase isoform SRK4 - Spongilla lacustris| (Freshwater sponge) Length = 506 Score = 116 bits (290), Expect = 4e-25 Identities = 75/256 (29%), Positives = 121/256 (47%), Gaps = 1/256 (0%) Frame = +1 Query: 172 EQLIIEEELSKDKDGEDIGRFGKVFKGRCFGL-EVAVKIPKVQELSPEQLEKFKQEVAIN 348 E+ IE++ K G G+FG+V++G G VAVK K +S +E+F +E +I Sbjct: 231 EEWEIEKKQIKLLRGLGAGQFGEVWEGLWNGTTSVAVKTLKPGTMS---IEEFLEEASIM 287 Query: 349 SEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGM 528 ++ HP +++ C K +VTE R L L + + + GM Sbjct: 288 KQLRHPKLIQLYAVCTKEEPIYIVTELMKHGSLLEYLRGDGRSLKLPDLVDMCSQVASGM 347 Query: 529 IYIHAANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWMAPEML 708 Y+ N +H DL N+L+ + K+ADFGL + + G K W APE Sbjct: 348 SYLEQQNYIHRDLAARNILVGEHKICKVADFGLARVIDEEIYEAKLGAKFPIKWTAPEAA 407 Query: 709 LGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSY 888 + F K+D++SFGI+L++++T ++ + +YR P P G +KL Sbjct: 408 MYSRFTIKSDVWSFGIVLYEVITYGRFPYPGMTNAQVLEQIQ-QSYRMPRPMGCPEKLYA 466 Query: 889 LIHRCWHPQPALRPSF 936 ++ CW PA RP+F Sbjct: 467 IMMDCWREDPASRPTF 482
>P00530:FPS_FUJSV Tyrosine-protein kinase transforming protein FPS - Fujinami sarcoma| virus Length = 873 Score = 116 bits (290), Expect = 4e-25 Identities = 75/245 (30%), Positives = 115/245 (46%), Gaps = 4/245 (1%) Frame = +1 Query: 214 GEDIGR--FGKVFKGRCFGLEVAVKIPKVQELSPEQLE-KFKQEVAINSEINHPNVVRFL 384 GE IGR FG+VF GR V + +E P +L+ KF QE I + NHPN+VR + Sbjct: 615 GERIGRGNFGEVFSGRLRADNTPVAVKSCRETLPPELKAKFLQEARILKQCNHPNIVRLI 674 Query: 385 GACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLD 564 G C + +V E +K L + + +++ + GM Y+ + + +H D Sbjct: 675 GVCTQKQPIYIVMELVQGGDFLSFLRSKGPRLKMKKLIKMMENAAAGMEYLESKHCIHRD 734 Query: 565 LKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPL-WMAPEMLLGKPFDEKADI 741 L N L+ T KI+DFG++ D GG K P+ W APE L + ++D+ Sbjct: 735 LAARNCLVTEKNTLKISDFGMSRQEEDGVYASTGGMKQIPVKWTAPEALNYGWYSSESDV 794 Query: 742 YSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPA 921 +SFGI+LW+ + +A+ R P+ + + L+ RCW P Sbjct: 795 WSFGILLWEAFSLGAVPYANLSNQQTREAIE-QGVRLEPPEQCPEDVYRLMQRCWEYDPH 853 Query: 922 LRPSF 936 RPSF Sbjct: 854 RRPSF 858
>P42686:SRK1_SPOLA Tyrosine-protein kinase isoform SRK1 - Spongilla lacustris| (Freshwater sponge) Length = 505 Score = 115 bits (289), Expect = 5e-25 Identities = 69/238 (28%), Positives = 114/238 (47%), Gaps = 1/238 (0%) Frame = +1 Query: 226 GRFGKVFKGRCFGL-EVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGACLKP 402 G+FG+V++G G VAVK K +S +E+F QE +I + HP +++ C K Sbjct: 249 GQFGEVWEGLWNGTTSVAVKTLKPGTMS---VEEFLQEASIMKRLRHPKLIQLYAVCTKE 305 Query: 403 LNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDLKPENV 582 +VTE + L + + + +A + GM Y+ N +H DL N+ Sbjct: 306 EPIYIVTELMKYGSLLEYLRGEDGVLKIEQLVDVAAQVASGMSYLEQQNYIHRDLAARNI 365 Query: 583 LLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWMAPEMLLGKPFDEKADIYSFGIIL 762 L+ +G K+ADFGL + + H G K W APE + F K+D++SFG++L Sbjct: 366 LVGEHGICKVADFGLARVIDEEIYEAHTGAKFPIKWTAPEAAMYNRFTIKSDVWSFGVVL 425 Query: 763 WQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPALRPSF 936 ++++T ++ + NYR P P ++ ++ CW PA RP+F Sbjct: 426 YEIITYGRFPYPGMTNPEVLEKIQ-QNYRMPCPANCPKQFHDIMLDCWREDPASRPTF 482
>P28028:BRAF1_MOUSE B-Raf proto-oncogene serine/threonine-protein kinase - Mus musculus| (Mouse) Length = 804 Score = 115 bits (287), Expect = 8e-25 Identities = 84/274 (30%), Positives = 132/274 (48%), Gaps = 16/274 (5%) Frame = +1 Query: 4 VLCGSSPPSSTCREGPLPSKRYRCAAMQPSAGP------GTGAAIHD-----PFGVAKGF 150 V GS+ S LP A+Q S GP + ++ D G Sbjct: 425 VFRGSTTGLSATPPASLPGSLTNVKALQKSPGPQRERKSSSSSSSEDRSRMKTLGRRDSS 484 Query: 151 VGLEIPAEQLIIEEELSKDKDGEDIGRFGKVFKGRCFGLEVAVKIPKVQELSPEQLEKFK 330 EIP Q+ + + + G FG V+KG+ G +VAVK+ V +P+QL+ FK Sbjct: 485 DDWEIPDGQITVGQRIGS-------GSFGTVYKGKWHG-DVAVKMLNVTAPTPQQLQAFK 536 Query: 331 QEVAINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIAR 510 EV + + H N++ F+G KP +VT+ + + + IAR Sbjct: 537 NEVGVLRKTRHVNILLFMGYSTKP-QLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIAR 595 Query: 511 DIVKGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPK--GTP 684 +GM Y+HA +++H DLK N+ L + T KI DFGL ++ R S H + G+ Sbjct: 596 QTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVK-SRWSGSHQFEQLSGSI 654 Query: 685 LWMAPEMLL---GKPFDEKADIYSFGIILWQLLT 777 LWMAPE++ P+ ++D+Y+FGI+L++L+T Sbjct: 655 LWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMT 688
>P34908:BRAF1_COTJA B-Raf proto-oncogene serine/threonine-protein kinase - Coturnix| coturnix japonica (Japanese quail) Length = 807 Score = 115 bits (287), Expect = 8e-25 Identities = 84/272 (30%), Positives = 132/272 (48%), Gaps = 14/272 (5%) Frame = +1 Query: 4 VLCGSSPPSSTCREGPLPSKRYRCAAMQPSAGPG----TGAAIHD-----PFGVAKGFVG 156 V GS+ S LP A+Q S GP + ++ D G Sbjct: 430 VFRGSTAGLSATPPASLPGSLTNVKALQKSPGPQRERKSSSSSEDRNRMKTLGRRDSSDD 489 Query: 157 LEIPAEQLIIEEELSKDKDGEDIGRFGKVFKGRCFGLEVAVKIPKVQELSPEQLEKFKQE 336 EIP Q+ + + + G FG V+KG+ G +VAVK+ V +P+QL+ FK E Sbjct: 490 WEIPDGQITVGQRIGS-------GSFGTVYKGKWHG-DVAVKMLNVTAPTPQQLQAFKNE 541 Query: 337 VAINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDI 516 V + + H N++ F+G KP +VT+ + + + IAR Sbjct: 542 VGVLRKTRHVNILLFMGYSTKP-QLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQT 600 Query: 517 VKGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPK--GTPLW 690 +GM Y+HA +++H DLK N+ L + T KI DFGL ++ R S H + G+ LW Sbjct: 601 AQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVK-SRWSGSHQFEQLSGSILW 659 Query: 691 MAPEMLL---GKPFDEKADIYSFGIILWQLLT 777 MAPE++ P+ ++D+Y+FGI+L++L+T Sbjct: 660 MAPEVIRMQDKNPYSFQSDVYAFGIVLYELMT 691
>Q04982:BRAF1_CHICK B-Raf proto-oncogene serine/threonine-protein kinase - Gallus gallus| (Chicken) Length = 806 Score = 115 bits (287), Expect = 8e-25 Identities = 84/272 (30%), Positives = 132/272 (48%), Gaps = 14/272 (5%) Frame = +1 Query: 4 VLCGSSPPSSTCREGPLPSKRYRCAAMQPSAGPG----TGAAIHD-----PFGVAKGFVG 156 V GS+ S LP A+Q S GP + ++ D G Sbjct: 430 VFRGSTAGLSATPPASLPGSLTNVKALQKSPGPQRERKSSSSSEDRNRMKTLGRRDSSDD 489 Query: 157 LEIPAEQLIIEEELSKDKDGEDIGRFGKVFKGRCFGLEVAVKIPKVQELSPEQLEKFKQE 336 EIP Q+ + + + G FG V+KG+ G +VAVK+ V +P+QL+ FK E Sbjct: 490 WEIPDGQITVGQRIGS-------GSFGTVYKGKWHG-DVAVKMLNVTAPTPQQLQAFKNE 541 Query: 337 VAINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDI 516 V + + H N++ F+G KP +VT+ + + + IAR Sbjct: 542 VGVLRKTRHVNILLFMGYSTKP-QLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQT 600 Query: 517 VKGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPK--GTPLW 690 +GM Y+HA +++H DLK N+ L + T KI DFGL ++ R S H + G+ LW Sbjct: 601 AQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVK-SRWSGSHQFEQLSGSILW 659 Query: 691 MAPEMLL---GKPFDEKADIYSFGIILWQLLT 777 MAPE++ P+ ++D+Y+FGI+L++L+T Sbjct: 660 MAPEVIRMQDKNPYSFQSDVYAFGIVLYELMT 691
>P10533:RMIL_AVII1 Serine/threonine-protein kinase-transforming protein Rmil - Avian| retrovirus IC10 Length = 367 Score = 114 bits (286), Expect = 1e-24 Identities = 83/269 (30%), Positives = 131/269 (48%), Gaps = 14/269 (5%) Frame = +1 Query: 13 GSSPPSSTCREGPLPSKRYRCAAMQPSAGPG----TGAAIHD-----PFGVAKGFVGLEI 165 GS+ S LP A+Q S GP + ++ D G EI Sbjct: 3 GSTAGLSATPPASLPGSLTNVKALQKSPGPQRERKSSSSSEDRNRMKTLGRRDSSDDWEI 62 Query: 166 PAEQLIIEEELSKDKDGEDIGRFGKVFKGRCFGLEVAVKIPKVQELSPEQLEKFKQEVAI 345 P Q+ + + + G FG V+KG+ G +VAVK+ V +P+QL+ FK EV + Sbjct: 63 PDGQITVGQRIGS-------GSFGTVYKGKWHG-DVAVKMLNVTAPTPQQLQAFKNEVGV 114 Query: 346 NSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKG 525 + H N++ F+G KP +VT+ + + + IAR +G Sbjct: 115 LRKTRHVNILLFMGYSTKP-QLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQG 173 Query: 526 MIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPK--GTPLWMAP 699 M Y+HA +++H DLK N+ L + T KI DFGL ++ R S H + G+ LWMAP Sbjct: 174 MDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVK-SRWSGSHQFEQLSGSILWMAP 232 Query: 700 EMLL---GKPFDEKADIYSFGIILWQLLT 777 E++ P+ ++D+Y+FGI+L++L+T Sbjct: 233 EVIRMQDKNPYSFQSDVYAFGIVLYELMT 261
>P27966:RMIL_AVEVR Serine/threonine-protein kinase-transforming protein Rmil - Avian| rous-associated virus type 1 Length = 450 Score = 114 bits (286), Expect = 1e-24 Identities = 83/269 (30%), Positives = 131/269 (48%), Gaps = 14/269 (5%) Frame = +1 Query: 13 GSSPPSSTCREGPLPSKRYRCAAMQPSAGPG----TGAAIHD-----PFGVAKGFVGLEI 165 GS+ S LP A+Q S GP + ++ D G EI Sbjct: 19 GSTAGLSATPPASLPGSLTNVKALQKSPGPQRERKSSSSSEDRNRMKTLGRRDSSDDWEI 78 Query: 166 PAEQLIIEEELSKDKDGEDIGRFGKVFKGRCFGLEVAVKIPKVQELSPEQLEKFKQEVAI 345 P Q+ + + + G FG V+KG+ G +VAVK+ V +P+QL+ FK EV + Sbjct: 79 PDGQITVGQRIGS-------GSFGTVYKGKWHG-DVAVKMLNVTAPTPQQLQAFKNEVGV 130 Query: 346 NSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKG 525 + H N++ F+G KP +VT+ + + + IAR +G Sbjct: 131 LRKTRHVNILLFMGYSTKP-QLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQG 189 Query: 526 MIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPK--GTPLWMAP 699 M Y+HA +++H DLK N+ L + T KI DFGL ++ R S H + G+ LWMAP Sbjct: 190 MDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVK-SRWSGSHQFEQLSGSILWMAP 248 Query: 700 EMLL---GKPFDEKADIYSFGIILWQLLT 777 E++ P+ ++D+Y+FGI+L++L+T Sbjct: 249 EVIRMQDKNPYSFQSDVYAFGIVLYELMT 277
>P15056:BRAF1_HUMAN B-Raf proto-oncogene serine/threonine-protein kinase - Homo sapiens| (Human) Length = 766 Score = 114 bits (286), Expect = 1e-24 Identities = 83/269 (30%), Positives = 131/269 (48%), Gaps = 14/269 (5%) Frame = +1 Query: 13 GSSPPSSTCREGPLPSKRYRCAAMQPSAGPG----TGAAIHD-----PFGVAKGFVGLEI 165 GS+ S LP A+Q S GP + ++ D G EI Sbjct: 393 GSTTGLSATPPASLPGSLTNVKALQKSPGPQRERKSSSSSEDRNRMKTLGRRDSSDDWEI 452 Query: 166 PAEQLIIEEELSKDKDGEDIGRFGKVFKGRCFGLEVAVKIPKVQELSPEQLEKFKQEVAI 345 P Q+ + + + G FG V+KG+ G +VAVK+ V +P+QL+ FK EV + Sbjct: 453 PDGQITVGQRIGS-------GSFGTVYKGKWHG-DVAVKMLNVTAPTPQQLQAFKNEVGV 504 Query: 346 NSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKG 525 + H N++ F+G KP +VT+ + + + IAR +G Sbjct: 505 LRKTRHVNILLFMGYSTKP-QLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQG 563 Query: 526 MIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPK--GTPLWMAP 699 M Y+HA +++H DLK N+ L + T KI DFGL ++ R S H + G+ LWMAP Sbjct: 564 MDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVK-SRWSGSHQFEQLSGSILWMAP 622 Query: 700 EMLL---GKPFDEKADIYSFGIILWQLLT 777 E++ P+ ++D+Y+FGI+L++L+T Sbjct: 623 EVIRMQDKNPYSFQSDVYAFGIVLYELMT 651
>Q7T2V3:M3K10_XENLA Mitogen-activated protein kinase kinase kinase 10 - Xenopus laevis| (African clawed frog) Length = 1005 Score = 114 bits (285), Expect = 1e-24 Identities = 85/274 (31%), Positives = 123/274 (44%), Gaps = 13/274 (4%) Frame = +1 Query: 157 LEIPAEQLIIEEELSKDKDGEDIGRFGKVFKGRCFGLEVAVKIPK--VQELSPEQLEKFK 330 LEI ++L ++E + +G FGKV+KG EVAVK + E E + Sbjct: 111 LEIEFDELNLDEIIG-------VGGFGKVYKGLWRDEEVAVKAVRHDPDEDINVTAENVR 163 Query: 331 QEVAINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIAR 510 QE I + HPN++ G CLKP + LV E + K P + + A Sbjct: 164 QEAKIFCMLCHPNIIALTGVCLKPPHLCLVMEYARGGPLHRALAGKKVPAHVL--VNWAV 221 Query: 511 DIVKGMIYIH---AANLVHLDLKPENVLLD--------FNGTAKIADFGLTVIRLDRQSL 657 I KGM Y+H ++H DL N+L+ FN T I DFGL + Q Sbjct: 222 QIAKGMTYLHNEAIVPIIHRDLGSSNILILEKAENDDLFNKTLNITDFGLA---REWQKT 278 Query: 658 LHGGPKGTPLWMAPEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAI 837 GT WMAPE++ F + +D++SFG++LW+LLT VA+ Sbjct: 279 TKMSAAGTYAWMAPEVIRLSLFSKSSDVWSFGVLLWELLT-GEVPYREIDALAVAYGVAM 337 Query: 838 NNYRPPMPQGTNQKLSYLIHRCWHPQPALRPSFT 939 N P+P + ++ CW P P RP+F+ Sbjct: 338 NKLTLPIPSTCPEPFVRILEACWDPDPHSRPTFS 371
>Q3UVC0:KSR2_MOUSE Kinase suppressor of Ras 2 - Mus musculus (Mouse)| Length = 959 Score = 114 bits (284), Expect = 2e-24 Identities = 85/280 (30%), Positives = 138/280 (49%), Gaps = 18/280 (6%) Frame = +1 Query: 160 EIPAEQLIIEEELSKDKDGEDIGRFGKVFKGRCFGLEVAVKIPKVQELSPEQLEKFKQEV 339 +IP EQL I E + K GRFG+V+ GR G EVA+++ ++ + +QL+ FK+EV Sbjct: 670 DIPFEQLEIGELIGK-------GRFGQVYHGRWHG-EVAIRLIDIERDNEDQLKAFKREV 721 Query: 340 AINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIV 519 + H NVV F+GAC+ P + ++T + L + + +IA++IV Sbjct: 722 MAYRQTRHENVVLFMGACMSPPHLAIITSLCKGRTLYSVVRDAKIVLDVNKTRQIAQEIV 781 Query: 520 KGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPL---- 687 KGM Y+HA ++H DLK +NV D NG I DFGL I +L G + L Sbjct: 782 KGMGYLHAKGILHKDLKSKNVFYD-NGKVVITDFGLFSI----SGVLQAGRRDDKLRIQN 836 Query: 688 -W---MAPEMLL---------GKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKA 828 W +APE++ PF + +D+++ G I ++L R + Sbjct: 837 GWLCHLAPEIIRQLSPDTEEDKLPFSKHSDVFALGTIWYELHAREWPFKTQPAEAIIWQM 896 Query: 829 VAINNYRPPMPQ-GTNQKLSYLIHRCWHPQPALRPSFTEI 945 +P + Q G +++S ++ CW + RP+FT++ Sbjct: 897 G--TGMKPNLSQIGMGKEISDILLFCWAFEQEERPTFTKL 934
>Q6VAB6:KSR2_HUMAN Kinase suppressor of Ras 2 - Homo sapiens (Human)| Length = 950 Score = 113 bits (283), Expect = 2e-24 Identities = 85/280 (30%), Positives = 138/280 (49%), Gaps = 18/280 (6%) Frame = +1 Query: 160 EIPAEQLIIEEELSKDKDGEDIGRFGKVFKGRCFGLEVAVKIPKVQELSPEQLEKFKQEV 339 +IP EQL I E + K GRFG+V+ GR G EVA+++ ++ + +QL+ FK+EV Sbjct: 660 DIPFEQLEIGELIGK-------GRFGQVYHGRWHG-EVAIRLIDIERDNEDQLKAFKREV 711 Query: 340 AINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIV 519 + H NVV F+GAC+ P + ++T + L + + +IA++IV Sbjct: 712 MAYRQTRHENVVLFMGACMSPPHLAIITSLCKGRTLYSVVRDAKIVLDVNKTRQIAQEIV 771 Query: 520 KGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPL---- 687 KGM Y+HA ++H DLK +NV D NG I DFGL I +L G + L Sbjct: 772 KGMGYLHAKGILHKDLKSKNVFYD-NGKVVITDFGLFSI----SGVLQAGRREDKLRIQN 826 Query: 688 -W---MAPEMLL---------GKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKA 828 W +APE++ PF + +D+++ G I ++L R + Sbjct: 827 GWLCHLAPEIIRQLSPDTEEDKLPFSKHSDVFALGTIWYELHAREWPFKTQPAEAIIWQM 886 Query: 829 VAINNYRPPMPQ-GTNQKLSYLIHRCWHPQPALRPSFTEI 945 +P + Q G +++S ++ CW + RP+FT++ Sbjct: 887 G--TGMKPNLSQIGMGKEISDILLFCWAFEQEERPTFTKL 924
>P16591:FER_HUMAN Proto-oncogene tyrosine-protein kinase FER - Homo sapiens (Human)| Length = 822 Score = 113 bits (283), Expect = 2e-24 Identities = 75/260 (28%), Positives = 125/260 (48%), Gaps = 2/260 (0%) Frame = +1 Query: 172 EQLIIEEELSKDKDGEDIGRFGKVFKGRCFGLEVAVKIPKVQELSPEQLE-KFKQEVAIN 348 E +I+ E L K G FG+V+KG + +V + +E P++L+ KF QE I Sbjct: 561 EDVILGELLGK-------GNFGEVYKGTLKD-KTSVAVKTCKEDLPQELKIKFLQEAKIL 612 Query: 349 SEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGM 528 + +HPN+V+ +G C + ++ E K L L + ++ + D GM Sbjct: 613 KQYDHPNIVKLIGVCTQRQPVYIIMELVSGGDFLTFLRRKKDELKLKQLVKFSLDAAAGM 672 Query: 529 IYIHAANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPL-WMAPEM 705 +Y+ + N +H DL N L+ N KI+DFG++ + D G K P+ W APE Sbjct: 673 LYLESKNCIHRDLAARNCLVGENNVLKISDFGMS-RQEDGGVYSSSGLKQIPIKWTAPEA 731 Query: 706 LLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLS 885 L + ++D++SFGI+LW+ + + V YR PQ + +S Sbjct: 732 LNYGRYSSESDVWSFGILLWETFSLGVCPYPGMTNQQAREQVE-RGYRMSAPQHCPEDIS 790 Query: 886 YLIHRCWHPQPALRPSFTEI 945 ++ +CW +P RP F+E+ Sbjct: 791 KIMMKCWDYKPENRPKFSEL 810
>Q66L42:M3K10_MOUSE Mitogen-activated protein kinase kinase kinase 10 - Mus musculus| (Mouse) Length = 940 Score = 113 bits (282), Expect = 3e-24 Identities = 84/278 (30%), Positives = 125/278 (44%), Gaps = 16/278 (5%) Frame = +1 Query: 160 EIPAEQLIIEEELSKDKDGEDIGRFGKVFKGRCFGLEVAVKIPKVQELSPEQ-----LEK 324 EIP +L +EE + +G FGKV++ G EVAVK + L PE+ E+ Sbjct: 92 EIPFHELQLEEIIG-------VGGFGKVYRAVWRGEEVAVKAAR---LDPERDPAVTAEQ 141 Query: 325 FKQEVAINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRI 504 +QE + + HPN++ GACL P N LV E + + P + + Sbjct: 142 VRQEARLFGALQHPNIIALRGACLSPPNLCLVMEYARGGALSRVLAGRRVPPHVL--VNW 199 Query: 505 ARDIVKGMIYIH---AANLVHLDLKPENVLLD--------FNGTAKIADFGLTVIRLDRQ 651 A + +GM Y+H ++H DLK N+L+ + KI DFGL + Sbjct: 200 AVQVARGMNYLHNDAPVPIIHRDLKSINILILEAIENHNLADTVLKITDFGLA---REWH 256 Query: 652 SLLHGGPKGTPLWMAPEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAV 831 GT WMAPE++ F + +D++SFG++LW+LLT V Sbjct: 257 KTTKMSAAGTYAWMAPEVIRLSLFSKSSDVWSFGVLLWELLT-GEVPYREIDALAVAYGV 315 Query: 832 AINNYRPPMPQGTNQKLSYLIHRCWHPQPALRPSFTEI 945 A+N P+P + + L+ CW P P RP F I Sbjct: 316 AMNKLTLPIPSTCPEPFARLLEECWDPDPHGRPDFGSI 353
>P09760:FER_RAT Proto-oncogene tyrosine-protein kinase FER - Rattus norvegicus| (Rat) Length = 323 Score = 113 bits (282), Expect = 3e-24 Identities = 72/242 (29%), Positives = 117/242 (48%), Gaps = 2/242 (0%) Frame = +1 Query: 226 GRFGKVFKGRCFG-LEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGACLKP 402 G FG+V+KG VAVK K ++L E KF QE I + +HPN+V+ +G C + Sbjct: 73 GNFGEVYKGTLKDKTPVAVKTCK-EDLPQELKIKFLQEAKILKQYDHPNIVKLIGVCTQR 131 Query: 403 LNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDLKPENV 582 ++ E + L L + +R + D+ GM+Y+ N +H DL N Sbjct: 132 QPVYIIMELVPGGDFLSFLRKRKDELKLKQLVRFSLDVAAGMLYLEGKNCIHRDLAARNC 191 Query: 583 LLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPL-WMAPEMLLGKPFDEKADIYSFGII 759 L+ N T KI+DFG++ + D G K P+ W APE L + ++D++SFGI+ Sbjct: 192 LVGENNTLKISDFGMS-RQEDGGVYSSSGLKQIPIKWTAPEALNYGRYSSESDVWSFGIL 250 Query: 760 LWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPALRPSFT 939 LW+ + + V YR PQ +++ ++ +CW +P RP F+ Sbjct: 251 LWETFSLGVCPYPGMTNQQAREQVE-RGYRMSAPQNCPEEIFTIMMKCWDYKPENRPKFS 309 Query: 940 EI 945 ++ Sbjct: 310 DL 311
>P51813:BMX_HUMAN Cytoplasmic tyrosine-protein kinase BMX - Homo sapiens (Human)| Length = 675 Score = 113 bits (282), Expect = 3e-24 Identities = 75/276 (27%), Positives = 132/276 (47%), Gaps = 3/276 (1%) Frame = +1 Query: 127 PFGVAKGFVGLEIPAEQLIIEEELSKDKDGEDIGRFGKVFKGRCFG-LEVAVKIPKVQEL 303 P V+ G E+ E++ + +EL G+FG V G+ G +VAVK+ K + Sbjct: 400 PDSVSLGNGIWELKREEITLLKELGS-------GQFGVVQLGKWKGQYDVAVKMIKEGSM 452 Query: 304 SPEQLEKFKQEVAINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNKARPLS 483 S ++ F QE +++HP +V+F G C K +VTE + + L Sbjct: 453 SEDE---FFQEAQTMMKLSHPKLVKFYGVCSKEYPIYIVTEYISNGCLLNYLRSHGKGLE 509 Query: 484 LARRMRIARDIVKGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLH 663 ++ + + D+ +GM ++ + +H DL N L+D + K++DFG+T LD Q + Sbjct: 510 PSQLLEMCYDVCEGMAFLESHQFIHRDLAARNCLVDRDLCVKVSDFGMTRYVLDDQYVSS 569 Query: 664 GGPKGTPLWMAPEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINN 843 G K W APE+ + K+D+++FGI++W++ + + V+ + Sbjct: 570 VGTKFPVKWSAPEVFHYFKYSSKSDVWAFGILMWEVFSLGKQPYDLYDNSQVVLKVSQGH 629 Query: 844 --YRPPMPQGTNQKLSYLIHRCWHPQPALRPSFTEI 945 YRP + T ++ Y CWH P RP+F ++ Sbjct: 630 RLYRPHLASDTIYQIMY---SCWHELPEKRPTFQQL 662 Score = 35.8 bits (81), Expect = 0.62 Identities = 31/102 (30%), Positives = 49/102 (48%), Gaps = 7/102 (6%) Frame = +1 Query: 1390 ERMANILPRPWFYGDLDKDAAFELLRNK-QPGTFLVRFSSNPEHVG------FVISVVDH 1548 E N+ WF G++ + + +LLR K + G F+VR N VG F +V D Sbjct: 286 EEEENLDDYDWFAGNISRSQSEQLLRQKGKEGAFMVR---NSSQVGMYTVSLFSKAVNDK 342 Query: 1549 KNTVVHIRVKHNAGSERPFMLLGDSTNASYSSLEEVILKNKH 1674 K TV H V NA ++ L + N + S+ ++I ++H Sbjct: 343 KGTVKHYHVHTNAENK-----LYLAENYCFDSIPKLIHYHQH 379
>P11346:KRAF1_DROME Raf homolog serine/threonine-protein kinase dRAF-1 - Drosophila| melanogaster (Fruit fly) Length = 739 Score = 112 bits (281), Expect = 4e-24 Identities = 83/268 (30%), Positives = 126/268 (47%), Gaps = 10/268 (3%) Frame = +1 Query: 178 LIIEEELSKDKDGEDIGRFGKVFKGRCFGLEVAVKIPKVQELSPEQLEKFKQEVAINSEI 357 ++ EE L + G G FG V++ G VAVK V+ SP QL+ FK EVA+ + Sbjct: 424 ILAEEILIGPRIGS--GSFGTVYRAHWHG-PVAVKTLNVKTPSPAQLQAFKNEVAMLKKT 480 Query: 358 NHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYI 537 H N++ F+G KP + +VT+ L + I R + +GM Y+ Sbjct: 481 RHCNILLFMGCVSKP-SLAIVTQWCEGSSLYKHVHVSETKFKLNTLIDIGRQVAQGMDYL 539 Query: 538 HAANLVHLDLKPENVLLDFNGTAKIADFGLTVIRL----DRQSLLHGGPKGTPLWMAPEM 705 HA N++H DLK N+ L + + KI DFGL + ++Q+ P G+ LWMAPE+ Sbjct: 540 HAKNIIHRDLKSNNIFLHEDLSVKIGDFGLATAKTRWSGEKQA---NQPTGSILWMAPEV 596 Query: 706 LLGK---PFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQ---G 867 + + P+ ++D+Y+FGI++++LL + V RP M Q Sbjct: 597 IRMQELNPYSFQSDVYAFGIVMYELLAECLPYGHISNKDQILFMVGRGLLRPDMSQVRSD 656 Query: 868 TNQKLSYLIHRCWHPQPALRPSFTEIDN 951 Q L L C P RP F + N Sbjct: 657 APQALKRLAEDCIKYTPKDRPLFRPLLN 684
>P70451:FER_MOUSE Proto-oncogene tyrosine-protein kinase FER - Mus musculus (Mouse)| Length = 823 Score = 112 bits (281), Expect = 4e-24 Identities = 70/242 (28%), Positives = 118/242 (48%), Gaps = 2/242 (0%) Frame = +1 Query: 226 GRFGKVFKGRCFGLEVAVKIPKVQELSPEQLE-KFKQEVAINSEINHPNVVRFLGACLKP 402 G FG+V+KG + V I +E P++L+ KF QE I + +HPN+V+ +G C + Sbjct: 573 GNFGEVYKGTLKD-KTPVAIKTCKEDLPQELKIKFLQEAKILKQYDHPNIVKLIGVCTQR 631 Query: 403 LNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDLKPENV 582 ++ E + L L + +R + D+ GM+Y+ + N +H DL N Sbjct: 632 QPVYIIMELVPGGDFLTFLRKRKDELKLKQLVRFSLDVAAGMLYLESKNCIHRDLAARNC 691 Query: 583 LLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPL-WMAPEMLLGKPFDEKADIYSFGII 759 L+ N T KI+DFG++ + D G K P+ W APE L + ++D++SFGI+ Sbjct: 692 LVGENNTLKISDFGMS-RQEDGGVYSSSGLKQIPIKWTAPEALNYGRYSSESDVWSFGIL 750 Query: 760 LWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPALRPSFT 939 LW+ + + V YR PQ +++ ++ +CW +P RP F Sbjct: 751 LWETFSLGVCPYPGMTNQQAREQVE-RGYRMSAPQNCPEEVFTIMMKCWDYKPENRPKFN 809 Query: 940 EI 945 ++ Sbjct: 810 DL 811
>P00527:YES_AVISY Tyrosine-protein kinase transforming protein YES - Avian sarcoma| virus (strain Y73) Length = 528 Score = 112 bits (279), Expect = 7e-24 Identities = 86/266 (32%), Positives = 124/266 (46%), Gaps = 2/266 (0%) Frame = +1 Query: 160 EIPAEQLIIEEELSKDKDGEDIGRFGKVFKGRCFGL-EVAVKIPKVQELSPEQLEKFKQE 336 EIP E L +E +L + G FG+V+ G G +VA+K K+ + PE F QE Sbjct: 261 EIPRESLRLEVKLGQ-------GCFGEVWMGTWNGTTKVAIKTLKLGTMMPEA---FLQE 310 Query: 337 VAINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSN-KARPLSLARRMRIARD 513 I ++ H +V L A + +VTE + + L L + + +A Sbjct: 311 AQIMKKLRHDKLVP-LYAVVSEEPIYIVTEFMTKGSLLDFLKEGEGKFLKLPQLVDMAAQ 369 Query: 514 IVKGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWM 693 I GM YI N +H DL+ N+L+ N KIADFGL + D + G K W Sbjct: 370 IADGMAYIERMNYIHRDLRAANILVGDNLVCKIADFGLARLIEDNEYTARQGAKFPIKWT 429 Query: 694 APEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTN 873 APE L F K+D++SFGI+L +L+T+ ++ V YR P PQG Sbjct: 430 APEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMVNREVLEQVE-RGYRMPCPQGCP 488 Query: 874 QKLSYLIHRCWHPQPALRPSFTEIDN 951 + L L+ CW P RP+F I + Sbjct: 489 ESLHELMKLCWKKDPDERPTFEYIQS 514
>P27446:FYN_XIPHE Proto-oncogene tyrosine-protein kinase FYN - Xiphophorus helleri| Length = 537 Score = 111 bits (278), Expect = 9e-24 Identities = 88/276 (31%), Positives = 127/276 (46%), Gaps = 2/276 (0%) Frame = +1 Query: 160 EIPAEQLIIEEELSKDKDGEDIGRFGKVFKGRCFGL-EVAVKIPKVQELSPEQLEKFKQE 336 EIP E L + + L G+FG+V+ G G +VAVK K +SPE F +E Sbjct: 265 EIPRESLQLIKRLGN-------GQFGEVWMGTWNGTTKVAVKTLKPGTMSPES---FLEE 314 Query: 337 VAINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSN-KARPLSLARRMRIARD 513 I ++ H +V+ L A + +VTE + + R L L + +A Sbjct: 315 AQIMKKLRHDKLVQ-LYAVVSEEPIYIVTEYMSKGSLLDFLKDGEGRALKLPNLVDMAAQ 373 Query: 514 IVKGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWM 693 + GM YI N +H DL+ N+L+ N KIADFGL + D + G K W Sbjct: 374 VAAGMAYIERMNYIHRDLRSANILVGDNLVCKIADFGLARLIEDNEYTARQGAKFPIKWT 433 Query: 694 APEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTN 873 APE L F K+D++SFGI+L +L+T+ ++ V YR P PQ Sbjct: 434 APEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVE-RGYRMPCPQDCP 492 Query: 874 QKLSYLIHRCWHPQPALRPSFTEIDNAYLQPIIVET 981 L L+ +CW P RP+F E A+L+ T Sbjct: 493 ASLHELMLQCWKKDPEERPTF-EYLQAFLEDYFTAT 527
>P13116:SRC2_XENLA Tyrosine-protein kinase Src-2 - Xenopus laevis (African clawed frog)| Length = 532 Score = 111 bits (277), Expect = 1e-23 Identities = 93/307 (30%), Positives = 136/307 (44%), Gaps = 2/307 (0%) Frame = +1 Query: 67 YRCAAMQPSAGPGTGAAIHDPFGVAKGFVGLEIPAEQLIIEEELSKDKDGEDIGRFGKVF 246 +R A+ P+A P T D + EIP + L +E +L + G FG+V+ Sbjct: 238 HRLTAVCPTAKPQTQGLSKDAW---------EIPRDSLRLELKLGQ-------GCFGEVW 281 Query: 247 KGRCFGL-EVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGACLKPLNFRLVT 423 G G VA+K K +SPE F QE + ++ H +V+ L A + +VT Sbjct: 282 MGTWNGTTRVAIKTLKPGTMSPEA---FLQEAQVMKKLRHEKLVQ-LYAVVSEEPIYIVT 337 Query: 424 EXXXXXXXXXXXSNK-ARPLSLARRMRIARDIVKGMIYIHAANLVHLDLKPENVLLDFNG 600 E + R L L + + +A I GM Y+ N VH DL+ N+L+ N Sbjct: 338 EYMSKGSLLDFLKGEMGRYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENL 397 Query: 601 TAKIADFGLTVIRLDRQSLLHGGPKGTPLWMAPEMLLGKPFDEKADIYSFGIILWQLLTR 780 K+ADFGL + D + G K W APE L F K+D++SFGI+L +L T+ Sbjct: 398 VCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTK 457 Query: 781 XXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPALRPSFTEIDNAYL 960 + V YR P P + L L+ +CW P RP+F E A+L Sbjct: 458 GRVPYPGMVNREVLDQVE-RGYRMPCPPDCPESLHDLMFQCWRKDPEERPTF-EYLQAFL 515 Query: 961 QPIIVET 981 + T Sbjct: 516 EDYFTAT 522
>Q8BKG3:PTK7_MOUSE Tyrosine-protein kinase-like 7 precursor - Mus musculus (Mouse)| Length = 1062 Score = 111 bits (277), Expect = 1e-23 Identities = 71/252 (28%), Positives = 114/252 (45%), Gaps = 14/252 (5%) Frame = +1 Query: 232 FGKVFKGRCFGLE-----VAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGACL 396 FG+VF + G+E V + +Q +Q F++EV + ++NH NVVR LG C Sbjct: 799 FGEVFLAKAQGVEEGATETLVLVKSLQSRDEQQQLDFRREVEMFGKLNHANVVRLLGLCR 858 Query: 397 KPLNFRLVTEXXXXXXXXXXX--------SNKARPLSLARRMRIARDIVKGMIYIHAANL 552 + +V E K++PLS +++ + + GM ++ Sbjct: 859 EAEPHYMVLEYVDLGDLKQFLRISKNKDEKLKSQPLSTKQKVALCSQVALGMEHLSNNRF 918 Query: 553 VHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPL-WMAPEMLLGKPFDE 729 VH DL N L+ K++ GL+ + H PL WM+PE +L F Sbjct: 919 VHKDLAARNCLISAQRQVKVSALGLSK-DVYNSEYYHFRQAWVPLRWMSPEAVLEGDFST 977 Query: 730 KADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWH 909 K+D+++FG+++W++ T + + R P P+G KL L+ RCW Sbjct: 978 KSDVWAFGVLMWEVFTHGEMPHGGQADDEVLADLQAGKARLPQPEGCPSKLYRLMQRCWA 1037 Query: 910 PQPALRPSFTEI 945 P P RPSF+EI Sbjct: 1038 PNPKDRPSFSEI 1049
>Q02779:M3K10_HUMAN Mitogen-activated protein kinase kinase kinase 10 - Homo sapiens| (Human) Length = 954 Score = 111 bits (277), Expect = 1e-23 Identities = 96/318 (30%), Positives = 140/318 (44%), Gaps = 18/318 (5%) Frame = +1 Query: 46 GPLPSKRYRCAAMQPS--AGPGTGAAIHDPFGVAKGFVGLEIPAEQLIIEEELSKDKDGE 219 G LPS R + PS PG AA P G+ + EIP +L +EE + Sbjct: 61 GQLPSGR---VGVFPSNYVAPGAPAA---PAGLQ---LPQEIPFHELQLEEIIG------ 105 Query: 220 DIGRFGKVFKGRCFGLEVAVKIPKVQELSPEQ-----LEKFKQEVAINSEINHPNVVRFL 384 +G FGKV++ G EVAVK + L PE+ E+ QE + + HPN++ Sbjct: 106 -VGGFGKVYRALWRGEEVAVKAAR---LDPEKDPAVTAEQVCQEARLFGALQHPNIIALR 161 Query: 385 GACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIH---AANLV 555 GACL P + LV E + + P + + A + +GM Y+H ++ Sbjct: 162 GACLNPPHLCLVMEYARGGALSRVLAGRRVPPHVL--VNWAVQVARGMNYLHNDAPVPII 219 Query: 556 HLDLKPENVLLD--------FNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWMAPEMLL 711 H DLK N+L+ + KI DFGL + GT WMAPE++ Sbjct: 220 HRDLKSINILILEAIENHNLADTVLKITDFGLA---REWHKTTKMSAAGTYAWMAPEVIR 276 Query: 712 GKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYL 891 F + +D++SFG++LW+LLT VA+N P+P + + L Sbjct: 277 LSLFSKSSDVWSFGVLLWELLT-GEVPYREIDALAVAYGVAMNKLTLPIPSTCPEPFARL 335 Query: 892 IHRCWHPQPALRPSFTEI 945 + CW P P RP F I Sbjct: 336 LEECWDPDPHGRPDFGSI 353
>P09324:YES_CHICK Tyrosine-protein kinase Yes - Gallus gallus (Chicken)| Length = 541 Score = 110 bits (276), Expect = 2e-23 Identities = 86/266 (32%), Positives = 123/266 (46%), Gaps = 2/266 (0%) Frame = +1 Query: 160 EIPAEQLIIEEELSKDKDGEDIGRFGKVFKGRCFGL-EVAVKIPKVQELSPEQLEKFKQE 336 EIP E L +E +L + G FG+V+ G G +VA+K K + PE F QE Sbjct: 269 EIPRESLRLEVKLGQ-------GCFGEVWMGTWNGTTKVAIKTLKPGTMMPEA---FLQE 318 Query: 337 VAINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSN-KARPLSLARRMRIARD 513 I ++ H +V L A + +VTE + + L L + + +A Sbjct: 319 AQIMKKLRHDKLVP-LYAVVSEEPIYIVTEFMTKGSLLDFLKEGEGKFLKLPQLVDMAAQ 377 Query: 514 IVKGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWM 693 I GM YI N +H DL+ N+L+ N KIADFGL + D + G K W Sbjct: 378 IADGMAYIERMNYIHRDLRAANILVGDNLVCKIADFGLARLIEDNEYTARQGAKFPIKWT 437 Query: 694 APEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTN 873 APE L F K+D++SFGI+L +L+T+ ++ V YR P PQG Sbjct: 438 APEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMVNREVLEQVE-RGYRMPCPQGCP 496 Query: 874 QKLSYLIHRCWHPQPALRPSFTEIDN 951 + L L+ CW P RP+F I + Sbjct: 497 ESLHELMKLCWKKDPDERPTFEYIQS 522
>Q9Y6E0:STK24_HUMAN Serine/threonine-protein kinase 24 - Homo sapiens (Human)| Length = 443 Score = 110 bits (276), Expect = 2e-23 Identities = 80/259 (30%), Positives = 129/259 (49%), Gaps = 7/259 (2%) Frame = +1 Query: 190 EELSKDKDGEDIGRFGKVFKGRCFGLE--VAVKIPKVQELSPEQLEKFKQEVAINSEINH 363 EEL + G FG+VFKG + VA+KI ++E + +++E +QE+ + S+ + Sbjct: 33 EELFTKLEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEE-AEDEIEDIQQEITVLSQCDS 91 Query: 364 PNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHA 543 P V ++ G+ LK ++ E + PL + I R+I+KG+ Y+H+ Sbjct: 92 PYVTKYYGSYLKDTKLWIIMEYLGGGSALDLL--EPGPLDETQIATILREILKGLDYLHS 149 Query: 544 ANLVHLDLKPENVLLDFNGTAKIADFG----LTVIRLDRQSLLHGGPKGTPLWMAPEMLL 711 +H D+K NVLL +G K+ADFG LT ++ R + + GTP WMAPE++ Sbjct: 150 EKKIHRDIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRNTFV-----GTPFWMAPEVIK 204 Query: 712 GKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQK-LSY 888 +D KADI+S GI + L R + + NN PP +G K L Sbjct: 205 QSAYDSKADIWSLGITAIE-LARGEPPHSELHPMKVLFLIPKNN--PPTLEGNYSKPLKE 261 Query: 889 LIHRCWHPQPALRPSFTEI 945 + C + +P+ RP+ E+ Sbjct: 262 FVEACLNKEPSFRPTAKEL 280
>P10398:ARAF_HUMAN A-Raf proto-oncogene serine/threonine-protein kinase - Homo sapiens| (Human) Length = 606 Score = 110 bits (276), Expect = 2e-23 Identities = 63/190 (33%), Positives = 104/190 (54%), Gaps = 6/190 (3%) Frame = +1 Query: 226 GRFGKVFKGRCFGLEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGACLKPL 405 G FG VF+GR G +VAVK+ KV + + EQ + FK E+ + + H N++ F+G +P Sbjct: 319 GSFGTVFRGRWHG-DVAVKVLKVSQPTAEQAQAFKNEMQVLRKTRHVNILLFMGFMTRP- 376 Query: 406 NFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDLKPENVL 585 F ++T+ + + + +AR +GM Y+HA N++H DLK N+ Sbjct: 377 GFAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDYLHAKNIIHRDLKSNNIF 436 Query: 586 LDFNGTAKIADFGLTVIRL---DRQSLLHGGPKGTPLWMAPEMLL---GKPFDEKADIYS 747 L T KI DFGL ++ Q L P G+ LWMA E++ P+ ++D+Y+ Sbjct: 437 LHEGLTVKIGDFGLATVKTRWSGAQPLEQ--PSGSVLWMAAEVIRMQDPNPYSFQSDVYA 494 Query: 748 FGIILWQLLT 777 +G++L++L+T Sbjct: 495 YGVVLYELMT 504
>P27447:YES_XIPHE Tyrosine-protein kinase Yes - Xiphophorus helleri| Length = 544 Score = 110 bits (275), Expect = 2e-23 Identities = 90/297 (30%), Positives = 134/297 (45%), Gaps = 2/297 (0%) Frame = +1 Query: 67 YRCAAMQPSAGPGTGAAIHDPFGVAKGFVGLEIPAEQLIIEEELSKDKDGEDIGRFGKVF 246 Y+ + P P T G+AK EIP E L ++ L + G FG+V+ Sbjct: 250 YKLTTVCPQVKPQTQ-------GIAKD--AWEIPRESLRLDVRLGQ-------GCFGEVW 293 Query: 247 KGRCFGL-EVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGACLKPLNFRLVT 423 G G +VA+K K +SPE F +E I ++ H +V L A + +VT Sbjct: 294 MGTWNGTTKVAIKTLKPGTMSPEA---FLEEAQIMKKLRHDKLVP-LYAVVSEEPIYIVT 349 Query: 424 EXXXXXXXXXXXSN-KARPLSLARRMRIARDIVKGMIYIHAANLVHLDLKPENVLLDFNG 600 E + L L + + +A I GM +I N +H DL+ N+L+ N Sbjct: 350 EFMGKGSLLDFLKEGDGKHLKLPQLVDMASQIADGMAFIERMNYIHRDLRAANILVADNL 409 Query: 601 TAKIADFGLTVIRLDRQSLLHGGPKGTPLWMAPEMLLGKPFDEKADIYSFGIILWQLLTR 780 KIADFGL + D + G K W APE L F K+D++SFGI+L +L+T+ Sbjct: 410 VCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTK 469 Query: 781 XXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPALRPSFTEIDN 951 ++ V YR P PQG + L ++ +CW +P RP+F I + Sbjct: 470 GRVPYPGMVNREVLEQVD-RGYRMPCPQGCPESLHEMMRQCWKKEPDERPTFEYIQS 525
>P14056:ARAF_RAT A-Raf proto-oncogene serine/threonine-protein kinase - Rattus| norvegicus (Rat) Length = 604 Score = 110 bits (275), Expect = 2e-23 Identities = 63/190 (33%), Positives = 104/190 (54%), Gaps = 6/190 (3%) Frame = +1 Query: 226 GRFGKVFKGRCFGLEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGACLKPL 405 G FG VF+GR G +VAVK+ KV + + EQ + FK E+ + + H N++ F+G +P Sbjct: 317 GSFGTVFRGRWHG-DVAVKVLKVAQPTAEQAQAFKNEMQVLRKTRHVNILLFMGFMTRP- 374 Query: 406 NFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDLKPENVL 585 F ++T+ + + + +AR +GM Y+HA N++H DLK N+ Sbjct: 375 GFAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDYLHAKNIIHRDLKSNNIF 434 Query: 586 LDFNGTAKIADFGLTVIRL---DRQSLLHGGPKGTPLWMAPEMLL---GKPFDEKADIYS 747 L T KI DFGL ++ Q L P G+ LWMA E++ P+ ++D+Y+ Sbjct: 435 LHEGLTVKIGDFGLATVKTRWSGAQPLEQ--PSGSVLWMAAEVIRMQDPNPYSFQSDVYA 492 Query: 748 FGIILWQLLT 777 +G++L++L+T Sbjct: 493 YGVVLYELMT 502
>O19004:ARAF_PIG A-Raf proto-oncogene serine/threonine-protein kinase - Sus scrofa| (Pig) Length = 606 Score = 110 bits (275), Expect = 2e-23 Identities = 63/190 (33%), Positives = 104/190 (54%), Gaps = 6/190 (3%) Frame = +1 Query: 226 GRFGKVFKGRCFGLEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGACLKPL 405 G FG VF+GR G +VAVK+ KV + + EQ + FK E+ + + H N++ F+G +P Sbjct: 319 GSFGTVFRGRWHG-DVAVKVLKVAQPTAEQAQAFKNEMQVLRKTRHVNILLFMGFMTRP- 376 Query: 406 NFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDLKPENVL 585 F ++T+ + + + +AR +GM Y+HA N++H DLK N+ Sbjct: 377 GFAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDYLHAKNIIHRDLKSNNIF 436 Query: 586 LDFNGTAKIADFGLTVIRL---DRQSLLHGGPKGTPLWMAPEMLL---GKPFDEKADIYS 747 L T KI DFGL ++ Q L P G+ LWMA E++ P+ ++D+Y+ Sbjct: 437 LHEGLTVKIGDFGLATVKTRWSGAQPLEQ--PSGSVLWMAAEVIRMQDPNPYSFQSDVYA 494 Query: 748 FGIILWQLLT 777 +G++L++L+T Sbjct: 495 YGVVLYELMT 504
>P04627:ARAF_MOUSE A-Raf proto-oncogene serine/threonine-protein kinase - Mus musculus| (Mouse) Length = 604 Score = 110 bits (275), Expect = 2e-23 Identities = 63/190 (33%), Positives = 104/190 (54%), Gaps = 6/190 (3%) Frame = +1 Query: 226 GRFGKVFKGRCFGLEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGACLKPL 405 G FG VF+GR G +VAVK+ KV + + EQ + FK E+ + + H N++ F+G +P Sbjct: 317 GSFGTVFRGRWHG-DVAVKVLKVAQPTAEQAQAFKNEMQVLRKTRHVNILLFMGFMTRP- 374 Query: 406 NFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDLKPENVL 585 F ++T+ + + + +AR +GM Y+HA N++H DLK N+ Sbjct: 375 GFAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDYLHAKNIIHRDLKSNNIF 434 Query: 586 LDFNGTAKIADFGLTVIRL---DRQSLLHGGPKGTPLWMAPEMLL---GKPFDEKADIYS 747 L T KI DFGL ++ Q L P G+ LWMA E++ P+ ++D+Y+ Sbjct: 435 LHEGLTVKIGDFGLATVKTRWSGAQPLEQ--PSGSVLWMAAEVIRMQDPNPYSFQSDVYA 492 Query: 748 FGIILWQLLT 777 +G++L++L+T Sbjct: 493 YGVVLYELMT 502
>P63185:SRC_RSVSE Tyrosine-protein kinase transforming protein Src - Rous sarcoma virus| (strain Schmidt-Ruppin E) (RSV-SR-E) Length = 526 Score = 110 bits (274), Expect = 3e-23 Identities = 80/276 (28%), Positives = 121/276 (43%), Gaps = 1/276 (0%) Frame = +1 Query: 160 EIPAEQLIIEEELSKDKDGEDIGRFGKVFKGRCFGL-EVAVKIPKVQELSPEQLEKFKQE 336 EIP E L +E +L + G FG+V+ G G VA+K K +SPE F QE Sbjct: 261 EIPRESLRLEVKLGQ-------GCFGEVWMGTWNGTTRVAIKTLKPGTMSPEA---FLQE 310 Query: 337 VAINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDI 516 + ++ H +V+ + + ++ + L L + + +A I Sbjct: 311 AQVMKKLRHKKLVQLYAVVSEEPIYIVIEYMSKGSLLDFLKGEMGKYLRLPQLVDMAAQI 370 Query: 517 VKGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWMA 696 GM Y+ N VH DL+ N+L+ N K+ADFGL + D + G K W A Sbjct: 371 ASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTA 430 Query: 697 PEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQ 876 PE L F K+D++SFGI+L +L T+ + V YR P P + Sbjct: 431 PEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMGNGEVLDRVE-RGYRMPCPPECPE 489 Query: 877 KLSYLIHRCWHPQPALRPSFTEIDNAYLQPIIVETA 984 L L+ +CW P RP+F + L ++E A Sbjct: 490 SLHDLMSQCWRRDPEERPTFEYLQAQLLPACVLEVA 525
>P13115:SRC1_XENLA Tyrosine-protein kinase Src-1 - Xenopus laevis (African clawed frog)| Length = 532 Score = 110 bits (274), Expect = 3e-23 Identities = 92/307 (29%), Positives = 135/307 (43%), Gaps = 2/307 (0%) Frame = +1 Query: 67 YRCAAMQPSAGPGTGAAIHDPFGVAKGFVGLEIPAEQLIIEEELSKDKDGEDIGRFGKVF 246 +R + P+A P T D + EIP + L +E +L + G FG+V+ Sbjct: 238 HRLTTVCPTAKPQTQGLSRDAW---------EIPRDSLRLELKLGQ-------GCFGEVW 281 Query: 247 KGRCFGL-EVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGACLKPLNFRLVT 423 G G VA+K K +SPE F QE + ++ H +V+ L A + +VT Sbjct: 282 MGTWNGTTRVAIKTLKPGTMSPEA---FLQEAQVMKKLRHEKLVQ-LYAVVSEEPIYIVT 337 Query: 424 EXXXXXXXXXXXSNK-ARPLSLARRMRIARDIVKGMIYIHAANLVHLDLKPENVLLDFNG 600 E + R L L + + +A I GM Y+ N VH DL+ N+L+ N Sbjct: 338 EYISKGSLLDFLKGEMGRYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENL 397 Query: 601 TAKIADFGLTVIRLDRQSLLHGGPKGTPLWMAPEMLLGKPFDEKADIYSFGIILWQLLTR 780 K+ADFGL + D + G K W APE L F K+D++SFGI+L +L T+ Sbjct: 398 VCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTK 457 Query: 781 XXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPALRPSFTEIDNAYL 960 + V YR P P + L L+ +CW P RP+F E A+L Sbjct: 458 GRVPYPGMVNREVLDQVE-RGYRMPCPPDCPESLHDLMFQCWRKDPEERPTF-EYLQAFL 515 Query: 961 QPIIVET 981 + T Sbjct: 516 EDYFTAT 522
>P14616:INSRR_HUMAN Insulin receptor-related protein precursor - Homo sapiens (Human)| Length = 1297 Score = 110 bits (274), Expect = 3e-23 Identities = 85/278 (30%), Positives = 125/278 (44%), Gaps = 16/278 (5%) Frame = +1 Query: 160 EIPAEQLIIEEELSKDKDGEDIGRFGKVFKGRCFGLEVA-----VKIPKVQEL-SPEQLE 321 E+P EQ+ I EL + G FG V++G GLE V + V EL SP + Sbjct: 973 EVPREQISIIRELGQ-------GSFGMVYEGLARGLEAGEESTPVALKTVNELASPRECI 1025 Query: 322 KFKQEVAINSEINHPNVVRFLGAC--------LKPLNFRLVTEXXXXXXXXXXXSNKARP 477 +F +E ++ +VVR LG + L R + +N P Sbjct: 1026 EFLKEASVMKAFKCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSHLRSLRPEAENNPGLP 1085 Query: 478 L-SLARRMRIARDIVKGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQS 654 +L +++A +I GM Y+ A VH DL N ++ + T KI DFG+T + Sbjct: 1086 QPALGEMIQMAGEIADGMAYLAANKFVHRDLAARNCMVSQDFTVKIGDFGMTRDVYETDY 1145 Query: 655 LLHGGPKGTPL-WMAPEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAV 831 GG P+ WMAPE L F +D++SFG++LW+++T +K V Sbjct: 1146 YRKGGKGLLPVRWMAPESLKDGIFTTHSDVWSFGVVLWEIVTLAEQPYQGLSNEQVLKFV 1205 Query: 832 AINNYRPPMPQGTNQKLSYLIHRCWHPQPALRPSFTEI 945 + +G +L L+ RCW P P LRPSFT I Sbjct: 1206 MDGGVLEEL-EGCPLQLQELMSRCWQPNPRLRPSFTHI 1242
>P07332:FES_HUMAN Proto-oncogene tyrosine-protein kinase Fes/Fps - Homo sapiens (Human)| Length = 822 Score = 110 bits (274), Expect = 3e-23 Identities = 73/248 (29%), Positives = 112/248 (45%), Gaps = 4/248 (1%) Frame = +1 Query: 214 GEDIGR--FGKVFKGRCFGLEVAVKIPKVQELSPEQLE-KFKQEVAINSEINHPNVVRFL 384 GE IGR FG+VF GR V + +E P L+ KF QE I + +HPN+VR + Sbjct: 564 GEQIGRGNFGEVFSGRLRADNTLVAVKSCRETLPPDLKAKFLQEARILKQYSHPNIVRLI 623 Query: 385 GACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLD 564 G C + +V E + L + +++ D GM Y+ + +H D Sbjct: 624 GVCTQKQPIYIVMELVQGGDFLTFLRTEGARLRVKTLLQMVGDAAAGMEYLESKCCIHRD 683 Query: 565 LKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPL-WMAPEMLLGKPFDEKADI 741 L N L+ KI+DFG++ D GG + P+ W APE L + ++D+ Sbjct: 684 LAARNCLVTEKNVLKISDFGMSREEADGVYAASGGLRQVPVKWTAPEALNYGRYSSESDV 743 Query: 742 YSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPA 921 +SFGI+LW+ + + V R P P+ + L+ +CW +P Sbjct: 744 WSFGILLWETFSLGASPYPNLSNQQTREFVE-KGGRLPCPELCPDAVFRLMEQCWAYEPG 802 Query: 922 LRPSFTEI 945 RPSF+ I Sbjct: 803 QRPSFSTI 810
>Q9TTY2:FER_CANFA Proto-oncogene tyrosine-protein kinase FER - Canis familiaris (Dog)| Length = 823 Score = 109 bits (273), Expect = 3e-23 Identities = 69/242 (28%), Positives = 116/242 (47%), Gaps = 2/242 (0%) Frame = +1 Query: 226 GRFGKVFKGRCFGLEVAVKIPKVQELSPEQLE-KFKQEVAINSEINHPNVVRFLGACLKP 402 G FG+V+KG + AV + +E P++L+ KF QE I + +HPN+V+ +G C + Sbjct: 572 GNFGEVYKG-ILKDKTAVAVKTCKEDLPQELKIKFLQEAKILKQYDHPNIVKLIGVCTQR 630 Query: 403 LNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDLKPENV 582 ++ E K + L + ++ + D GM Y+ + N +H DL N Sbjct: 631 QPIYIIMELVPGGDFLSFLRKKKDEIKLKQLVKFSLDAASGMSYLESKNCIHRDLAARNC 690 Query: 583 LLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPL-WMAPEMLLGKPFDEKADIYSFGII 759 L+ N KI+DFG++ + D G K P+ W APE L + ++D++SFGI+ Sbjct: 691 LVGENNVLKISDFGMS-RQEDGGVYSSSGLKQIPIKWTAPEALNYGRYSSESDVWSFGIL 749 Query: 760 LWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPALRPSFT 939 LW+ + + V YR PQ + + ++ +CW +P RP F+ Sbjct: 750 LWETFSLGVCPYPGMTNQQATEQVE-RGYRISAPQHCPEDIFKIMMKCWDYKPENRPKFS 808 Query: 940 EI 945 E+ Sbjct: 809 EL 810
>Q28923:YES_CANFA Proto-oncogene tyrosine-protein kinase Yes - Canis familiaris (Dog)| Length = 539 Score = 109 bits (272), Expect = 4e-23 Identities = 85/266 (31%), Positives = 122/266 (45%), Gaps = 2/266 (0%) Frame = +1 Query: 160 EIPAEQLIIEEELSKDKDGEDIGRFGKVFKGRCFGL-EVAVKIPKVQELSPEQLEKFKQE 336 EIP E L +E +L + G FG+V+ G G +VA+K K+ + PE F QE Sbjct: 267 EIPRESLRLEVKLGQ-------GCFGEVWMGTWNGTTKVAIKTLKLGTMMPEA---FLQE 316 Query: 337 VAINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSN-KARPLSLARRMRIARD 513 I ++ H +V L A + +VTE + L L + + +A Sbjct: 317 AQIMKKLRHDKLVP-LYAVVSEEPIYIVTEFMSKGSLLDFLKEGDGKYLKLPQLVDMAAQ 375 Query: 514 IVKGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWM 693 I GM YI N +H DL+ N+L+ N KIADFGL + D + G K W Sbjct: 376 IADGMAYIERMNYIHRDLRAANILVGENLVCKIADFGLARLIEDNEYTARQGAKFPIKWT 435 Query: 694 APEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTN 873 APE L F K+D++SFGI+ +L T+ ++ V YR P PQG Sbjct: 436 APEAALYGRFTIKSDVWSFGILQTELTTKGRVPYPGMVNREVLEQVE-RGYRMPCPQGCP 494 Query: 874 QKLSYLIHRCWHPQPALRPSFTEIDN 951 + L L++ CW P RP+F I + Sbjct: 495 ESLHELMNLCWKKDPDERPTFEYIQS 520
>Q99KH8:STK24_MOUSE Serine/threonine-protein kinase 24 - Mus musculus (Mouse)| Length = 431 Score = 109 bits (272), Expect = 4e-23 Identities = 79/259 (30%), Positives = 129/259 (49%), Gaps = 7/259 (2%) Frame = +1 Query: 190 EELSKDKDGEDIGRFGKVFKGRCFGLE--VAVKIPKVQELSPEQLEKFKQEVAINSEINH 363 EEL + G FG+VFKG + VA+KI ++E + +++E +QE+ + S+ + Sbjct: 21 EELFTKLEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEE-AEDEIEDIQQEITVLSQCDS 79 Query: 364 PNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHA 543 P V ++ G+ LK ++ E + PL + I R+I+KG+ Y+H+ Sbjct: 80 PYVTKYYGSYLKDTKLWIIMEYLGGGSALDLL--EPGPLDEIQIATILREILKGLDYLHS 137 Query: 544 ANLVHLDLKPENVLLDFNGTAKIADFG----LTVIRLDRQSLLHGGPKGTPLWMAPEMLL 711 +H D+K NVLL +G K+ADFG LT ++ R + + GTP WMAPE++ Sbjct: 138 EKKIHRDIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRNTFV-----GTPFWMAPEVIK 192 Query: 712 GKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQK-LSY 888 +D KADI+S GI + L + + + NN PP +G K L Sbjct: 193 QSAYDSKADIWSLGITAIE-LAKGEPPHSELHPMKVLFLIPKNN--PPTLEGNYSKPLKE 249 Query: 889 LIHRCWHPQPALRPSFTEI 945 + C + +P+ RP+ E+ Sbjct: 250 FVEACLNKEPSFRPTAKEL 268
>P00524:SRC_RSVSA Tyrosine-protein kinase transforming protein Src - Avian leukosis| virus RSA (RSV-SRA) (Rous sarcoma virus (strain Schmidt-Ruppin A)) Length = 526 Score = 109 bits (272), Expect = 4e-23 Identities = 85/277 (30%), Positives = 125/277 (45%), Gaps = 2/277 (0%) Frame = +1 Query: 160 EIPAEQLIIEEELSKDKDGEDIGRFGKVFKGRCFGL-EVAVKIPKVQELSPEQLEKFKQE 336 EIP E L +E +L + G FG+V+ G G VA+K K +SPE F QE Sbjct: 261 EIPRESLRLEVKLGQ-------GCFGEVWMGTWNGTTRVAIKTLKPGTMSPEA---FLQE 310 Query: 337 VAINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNK-ARPLSLARRMRIARD 513 + ++ H +V+ L A + +VTE + + L L + + +A Sbjct: 311 AQVMKKLRHEKLVQ-LYAVVSEEPIYIVTEYMSKGSLLDFLKGEMGKYLRLPQLVDMAAQ 369 Query: 514 IVKGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWM 693 I GM Y+ N VH DL+ N+L+ N K+ADFGL + D + G K W Sbjct: 370 IASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWT 429 Query: 694 APEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTN 873 APE L F K+D++SFGI+L +L T+ + V YR P P Sbjct: 430 APEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMGNGEVLDRVE-RGYRMPCPPECP 488 Query: 874 QKLSYLIHRCWHPQPALRPSFTEIDNAYLQPIIVETA 984 + L L+ +CW P RP+F + L ++E A Sbjct: 489 ESLHDLMCQCWRRDPEERPTFEYLQAQLLPACVLEVA 525
>P25020:SRC_RSVH1 Tyrosine-protein kinase transforming protein Src - Rous sarcoma virus| (strain H-19) Length = 526 Score = 109 bits (272), Expect = 4e-23 Identities = 80/276 (28%), Positives = 121/276 (43%), Gaps = 1/276 (0%) Frame = +1 Query: 160 EIPAEQLIIEEELSKDKDGEDIGRFGKVFKGRCFGL-EVAVKIPKVQELSPEQLEKFKQE 336 EIP E L +E +L + G FG+V+ G G VA+K K +SPE F QE Sbjct: 261 EIPRESLRLEAKLGQ-------GCFGEVWMGTWNGTTRVAIKTLKPGTMSPEA---FLQE 310 Query: 337 VAINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDI 516 + ++ H +V+ + + ++ + L L + + +A I Sbjct: 311 AQVMKKLRHEKLVQLYAVVSEEPIYIVIEYMSKGSLLDFLKGEMGKYLRLPQLVDMAAQI 370 Query: 517 VKGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWMA 696 GM Y+ N VH DL+ N+L+ N K+ADFGL + D + G K W A Sbjct: 371 ASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTA 430 Query: 697 PEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQ 876 PE L F K+D++SFGI+L +L T+ + V YR P P + Sbjct: 431 PEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVE-RAYRMPCPPECPE 489 Query: 877 KLSYLIHRCWHPQPALRPSFTEIDNAYLQPIIVETA 984 L L+ +CW P RP+F + L ++E A Sbjct: 490 SLHDLMCQCWRKDPEERPTFKYLQAQLLPACVLEVA 525
>P12931:SRC_HUMAN Proto-oncogene tyrosine-protein kinase Src - Homo sapiens (Human)| Length = 536 Score = 109 bits (272), Expect = 4e-23 Identities = 91/307 (29%), Positives = 136/307 (44%), Gaps = 2/307 (0%) Frame = +1 Query: 67 YRCAAMQPSAGPGTGAAIHDPFGVAKGFVGLEIPAEQLIIEEELSKDKDGEDIGRFGKVF 246 +R + P++ P T D + EIP E L +E +L + G FG+V+ Sbjct: 242 HRLTTVCPTSKPQTQGLAKDAW---------EIPRESLRLEVKLGQ-------GCFGEVW 285 Query: 247 KGRCFGL-EVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGACLKPLNFRLVT 423 G G VA+K K +SPE F QE + ++ H +V+ L A + +VT Sbjct: 286 MGTWNGTTRVAIKTLKPGTMSPEA---FLQEAQVMKKLRHEKLVQ-LYAVVSEEPIYIVT 341 Query: 424 EXXXXXXXXXXXSNKA-RPLSLARRMRIARDIVKGMIYIHAANLVHLDLKPENVLLDFNG 600 E + + L L + + +A I GM Y+ N VH DL+ N+L+ N Sbjct: 342 EYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENL 401 Query: 601 TAKIADFGLTVIRLDRQSLLHGGPKGTPLWMAPEMLLGKPFDEKADIYSFGIILWQLLTR 780 K+ADFGL + D + G K W APE L F K+D++SFGI+L +L T+ Sbjct: 402 VCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTK 461 Query: 781 XXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPALRPSFTEIDNAYL 960 + V YR P P + L L+ +CW +P RP+F E A+L Sbjct: 462 GRVPYPGMVNREVLDQVE-RGYRMPCPPECPESLHDLMCQCWRKEPEERPTF-EYLQAFL 519 Query: 961 QPIIVET 981 + T Sbjct: 520 EDYFTST 526
>P14084:SRC_AVISS Tyrosine-protein kinase transforming protein Src - Avian sarcoma| virus (strain S1) Length = 568 Score = 109 bits (272), Expect = 4e-23 Identities = 87/276 (31%), Positives = 125/276 (45%), Gaps = 2/276 (0%) Frame = +1 Query: 160 EIPAEQLIIEEELSKDKDGEDIGRFGKVFKGRCFGL-EVAVKIPKVQELSPEQLEKFKQE 336 EIP E L +E +L + G FG+V+ G G VA+K K +SPE F QE Sbjct: 261 EIPRESLRLEVKLGQ-------GCFGEVWMGTWNGTTRVAIKTLKPGTMSPEA---FLQE 310 Query: 337 VAINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNK-ARPLSLARRMRIARD 513 + ++ H +VR L A + +VTE + + L L + + +A Sbjct: 311 AQVMKKLRHEKLVR-LYAVVSEEPIYIVTEYMSKGSLLDFLKGEMGKYLRLPQLVDMAAQ 369 Query: 514 IVKGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWM 693 I GM Y+ N VH DL+ N+L+ N K+ADFGL + D + G K W Sbjct: 370 IASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWT 429 Query: 694 APEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTN 873 APE L F K+D++SFGI+L +L T+ + V YR P P Sbjct: 430 APEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVE-RGYRMPCPPECP 488 Query: 874 QKLSYLIHRCWHPQPALRPSFTEIDNAYLQPIIVET 981 + L L+ +CW P RP+F E A+L+ T Sbjct: 489 ESLHDLMCQCWRKDPEERPTF-EYLQAFLEDYFTST 523
>P00525:SRC_AVISR Tyrosine-protein kinase transforming protein Src - Avian sarcoma| virus (strain rASV1441) Length = 526 Score = 109 bits (272), Expect = 4e-23 Identities = 85/277 (30%), Positives = 125/277 (45%), Gaps = 2/277 (0%) Frame = +1 Query: 160 EIPAEQLIIEEELSKDKDGEDIGRFGKVFKGRCFGL-EVAVKIPKVQELSPEQLEKFKQE 336 EIP E L +E +L + G FG+V+ G G VA+K K +SPE F QE Sbjct: 261 EIPRESLRLEVKLGQ-------GCFGEVWMGTWNGTTRVAIKTLKPGTMSPEA---FLQE 310 Query: 337 VAINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNK-ARPLSLARRMRIARD 513 + ++ H +V+ L A + +VTE + + L L + + +A Sbjct: 311 AQVMKKLRHEKLVQ-LYAVVSEEPIYIVTEYMSKGSLLDFLKGEMGKYLRLPQLVDMAAQ 369 Query: 514 IVKGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWM 693 I GM Y+ N VH DL+ N+L+ N K+ADFGL + D + G K W Sbjct: 370 IASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWT 429 Query: 694 APEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTN 873 APE L F K+D++SFGI+L +L T+ + V YR P P Sbjct: 430 APEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMGNGEVLDRVE-RGYRMPCPPECP 488 Query: 874 QKLSYLIHRCWHPQPALRPSFTEIDNAYLQPIIVETA 984 + L L+ +CW P RP+F + L ++E A Sbjct: 489 ESLHDLMCQCWRRDPEERPTFEYLQAQLLPACVLEVA 525
>P53668:LIMK1_MOUSE LIM domain kinase 1 - Mus musculus (Mouse)| Length = 647 Score = 109 bits (272), Expect = 4e-23 Identities = 75/263 (28%), Positives = 116/263 (44%), Gaps = 25/263 (9%) Frame = +1 Query: 235 GKVFKGRCFGLEVAV------KIPKVQEL---SPEQLEKFKQEVAINSEINHPNVVRFLG 387 G+V CFG + V ++ ++EL E F +EV + + HPNV++F+G Sbjct: 342 GEVLGKGCFGQAIKVTHRETGEVMVMKELIRFDEETQRTFLKEVKVMRCLEHPNVLKFIG 401 Query: 388 ACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDL 567 K +TE N ++R+ A+DI GM Y+H+ N++H DL Sbjct: 402 VLYKDKRLNFITEYIKGGTLRGIIKNMDSQYPWSQRVSFAKDIASGMAYLHSMNIIHRDL 461 Query: 568 KPENVLLDFNGTAKIADFGLTVIRLDR-------QSLLHGGPK------GTPLWMAPEML 708 N L+ N +ADFGL + +D +SL K G P WMAPEM+ Sbjct: 462 NSHNCLVRENRNVVVADFGLARLMIDEKNQSEDLRSLKKPDRKKRYTVVGNPYWMAPEMI 521 Query: 709 LGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVA---INNYRPPMPQGTNQK 879 G+ +DEK D++SFGI+L +++ R ++ Y PP Sbjct: 522 NGRSYDEKVDVFSFGIVLCEIIGRVNADPDYLPRTMDFGLNVRGFLDRYCPP---NCPPS 578 Query: 880 LSYLIHRCWHPQPALRPSFTEID 948 + RC P RPSF +++ Sbjct: 579 FFPITVRCCDLDPEKRPSFVKLE 601
>P16879:FES_MOUSE Proto-oncogene tyrosine-protein kinase Fes/Fps - Mus musculus (Mouse)| Length = 820 Score = 109 bits (272), Expect = 4e-23 Identities = 73/248 (29%), Positives = 112/248 (45%), Gaps = 4/248 (1%) Frame = +1 Query: 214 GEDIGR--FGKVFKGRCFGLEVAVKIPKVQELSPEQLE-KFKQEVAINSEINHPNVVRFL 384 GE IGR FG+VF GR V + +E P L+ KF QE I + NHPN+VR + Sbjct: 562 GEQIGRGNFGEVFSGRLRADNTPVAVKSCRETLPPDLKAKFLQEARILKQYNHPNIVRLI 621 Query: 385 GACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLD 564 G C + +V E + L + +++ D GM Y+ + +H D Sbjct: 622 GVCTQKQPIYIVMELVQGGDFLTFLRTEGARLRVKTLLQMMGDAAAGMEYLESKCCIHRD 681 Query: 565 LKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPL-WMAPEMLLGKPFDEKADI 741 L N L+ KI+DFG++ D G + P+ W APE L + ++D+ Sbjct: 682 LAARNCLVTEKNVLKISDFGMSREEADGIYAACSGLRQVPVKWTAPEALNYGRYSSESDV 741 Query: 742 YSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPA 921 +SFGI+LW+ + + V +R P P+ + L+ +CW +P Sbjct: 742 WSFGILLWETFSLGASPYPNLTNQQTREFVE-KGHRLPCPELCPDAVFRLMEQCWAYEPG 800 Query: 922 LRPSFTEI 945 RPSF+ I Sbjct: 801 QRPSFSII 808
>P14238:FES_FELCA Proto-oncogene tyrosine-protein kinase Fes/Fps - Felis silvestris| catus (Cat) Length = 820 Score = 109 bits (272), Expect = 4e-23 Identities = 72/248 (29%), Positives = 112/248 (45%), Gaps = 4/248 (1%) Frame = +1 Query: 214 GEDIGR--FGKVFKGRCFGLEVAVKIPKVQELSPEQLE-KFKQEVAINSEINHPNVVRFL 384 GE IGR FG+VF GR V + +E P ++ KF QE I + +HPN+VR + Sbjct: 562 GEQIGRGNFGEVFSGRLRADNTLVAVKSCRETLPPDIKAKFLQEAKILKQYSHPNIVRLI 621 Query: 385 GACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLD 564 G C + +V E + L + +++ D GM Y+ + +H D Sbjct: 622 GVCTQKQPIYIVMELVQGGDFLTFLRTEGARLRMKTLLQMVGDAAAGMEYLESKCCIHRD 681 Query: 565 LKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPL-WMAPEMLLGKPFDEKADI 741 L N L+ KI+DFG++ D GG + P+ W APE L + ++D+ Sbjct: 682 LAARNCLVTEKNVLKISDFGMSREEADGIYAASGGLRQVPVKWTAPEALNYGRYSSESDV 741 Query: 742 YSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPA 921 +SFGI+LW+ + + V R P P+ + L+ +CW +P Sbjct: 742 WSFGILLWETFSLGASPYPNLSNQQTREFVE-KGGRLPCPELCPDAVFRLMEQCWAYEPG 800 Query: 922 LRPSFTEI 945 RPSF+ I Sbjct: 801 QRPSFSAI 808
>P07947:YES_HUMAN Proto-oncogene tyrosine-protein kinase Yes - Homo sapiens (Human)| Length = 543 Score = 108 bits (271), Expect = 6e-23 Identities = 85/266 (31%), Positives = 122/266 (45%), Gaps = 2/266 (0%) Frame = +1 Query: 160 EIPAEQLIIEEELSKDKDGEDIGRFGKVFKGRCFGL-EVAVKIPKVQELSPEQLEKFKQE 336 EIP E L +E +L + G FG+V+ G G +VA+K K + PE F QE Sbjct: 271 EIPRESLRLEVKLGQ-------GCFGEVWMGTWNGTTKVAIKTLKPGTMMPEA---FLQE 320 Query: 337 VAINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSN-KARPLSLARRMRIARD 513 I ++ H +V L A + +VTE + L L + + +A Sbjct: 321 AQIMKKLRHDKLVP-LYAVVSEEPIYIVTEFMSKGSLLDFLKEGDGKYLKLPQLVDMAAQ 379 Query: 514 IVKGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWM 693 I GM YI N +H DL+ N+L+ N KIADFGL + D + G K W Sbjct: 380 IADGMAYIERMNYIHRDLRAANILVGENLVCKIADFGLARLIEDNEYTARQGAKFPIKWT 439 Query: 694 APEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTN 873 APE L F K+D++SFGI+ +L+T+ ++ V YR P PQG Sbjct: 440 APEAALYGRFTIKSDVWSFGILQTELVTKGRVPYPGMVNREVLEQVE-RGYRMPCPQGCP 498 Query: 874 QKLSYLIHRCWHPQPALRPSFTEIDN 951 + L L++ CW P RP+F I + Sbjct: 499 ESLHELMNLCWKKDPDERPTFEYIQS 524
>P00526:SRC_RSVP Tyrosine-protein kinase transforming protein Src - Rous sarcoma virus| (strain Prague C) (RSV-PrC) Length = 526 Score = 108 bits (271), Expect = 6e-23 Identities = 85/307 (27%), Positives = 131/307 (42%), Gaps = 1/307 (0%) Frame = +1 Query: 67 YRCAAMQPSAGPGTGAAIHDPFGVAKGFVGLEIPAEQLIIEEELSKDKDGEDIGRFGKVF 246 +R A + P++ P T D + EIP E L +E +L + G FG+V+ Sbjct: 239 HRLANVCPTSKPQTQGLAKDAW---------EIPRESLRLEAKLGQ-------GCFGEVW 282 Query: 247 KGRCFGL-EVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGACLKPLNFRLVT 423 G VA+K K +SPE F QE + ++ H +V+ + + ++ Sbjct: 283 MGTWNDTTRVAIKTLKPGTMSPEA---FLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVIE 339 Query: 424 EXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDLKPENVLLDFNGT 603 + L L + + +A I GM Y+ N VH DL+ N+L+ N Sbjct: 340 YMSKGSLLDFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLV 399 Query: 604 AKIADFGLTVIRLDRQSLLHGGPKGTPLWMAPEMLLGKPFDEKADIYSFGIILWQLLTRX 783 K+ADFGL + D + G K W APE L F K+D++SFGI+L +L T+ Sbjct: 400 CKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKG 459 Query: 784 XXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPALRPSFTEIDNAYLQ 963 + V YR P P + L L+ +CW P RP+F + L Sbjct: 460 RVPYPGMVNREVLDQVE-RGYRMPCPPECPESLHDLMCQCWRKDPEERPTFKYLQAQLLP 518 Query: 964 PIIVETA 984 ++E A Sbjct: 519 ACVLEVA 525
>P15054:SRC_AVIS2 Tyrosine-protein kinase transforming protein Src - Avian sarcoma| virus (strain PR2257) Length = 587 Score = 108 bits (271), Expect = 6e-23 Identities = 87/279 (31%), Positives = 126/279 (45%), Gaps = 2/279 (0%) Frame = +1 Query: 160 EIPAEQLIIEEELSKDKDGEDIGRFGKVFKGRCFGL-EVAVKIPKVQELSPEQLEKFKQE 336 EIP E L +E +L + G FG+V+ G G VA+K K +SPE F QE Sbjct: 261 EIPRESLRLEVKLGQ-------GCFGEVWMGTWNGTTRVAIKTLKPGTMSPEA---FLQE 310 Query: 337 VAINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNK-ARPLSLARRMRIARD 513 + ++ H +V+ L A + +VTE + + L L + + +A Sbjct: 311 AQVMKKLRHEKLVQ-LYAVVSEEPIYIVTEYMSKGSLLDFLKGEMGKYLRLPQLVDMAAQ 369 Query: 514 IVKGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWM 693 I GM Y+ N VH DL+ N+L+ N K+ADFGL + D + G K W Sbjct: 370 IASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWT 429 Query: 694 APEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTN 873 APE L F K+D++SFGI+L +L T+ + V YR P P Sbjct: 430 APEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVE-RGYRMPCPPECP 488 Query: 874 QKLSYLIHRCWHPQPALRPSFTEIDNAYLQPIIVETAIP 990 + L L+ +CW P RP+F E A+L+ T P Sbjct: 489 ESLHDLMCQCWRKDPEERPTF-EYLQAFLEDYFTSTEPP 526
>Q61097:KSR1_MOUSE Kinase suppressor of Ras 1 - Mus musculus (Mouse)| Length = 873 Score = 108 bits (271), Expect = 6e-23 Identities = 72/220 (32%), Positives = 118/220 (53%), Gaps = 13/220 (5%) Frame = +1 Query: 160 EIPAEQLIIEEELSKDKDGEDIGRFGKVFKGRCFGLEVAVKIPKVQELSPEQLEKFKQEV 339 +IP EQ+ + E + + GR+G+V +GR G EVA+++ ++ + + L+ FK+EV Sbjct: 557 DIPFEQVELGEPIGQ-------GRWGRVHRGRWHG-EVAIRLLEMDGHNQDHLKLFKKEV 608 Query: 340 AINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIV 519 + H NVV F+GAC+ P + ++T + L + + +IA++I+ Sbjct: 609 MNYRQTRHENVVLFMGACMNPPHLAIITSFCKGRTLHSFVRDPKTSLDINKTRQIAQEII 668 Query: 520 KGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFGL----TVIRLDRQSLLHGGPKGTPL 687 KGM Y+HA +VH DLK +NV D NG I DFGL V+R +R+ Sbjct: 669 KGMGYLHAKGIVHKDLKSKNVFYD-NGKVVITDFGLFGISGVVREERRENQLKLSHDWLC 727 Query: 688 WMAP----EMLLGK-----PFDEKADIYSFGIILWQLLTR 780 ++AP EM+ G+ PF + AD+Y+FG + ++L R Sbjct: 728 YLAPEIVREMIPGRDEDQLPFSKAADVYAFGTVWYELQAR 767
>P00542:FES_FSVGA Tyrosine-protein kinase transforming protein Fes - Feline sarcoma| virus (strain Gardner-Arnstein) (Ga-FeSV) (Gardner-Arnstein feline leukemia oncovirus B) Length = 609 Score = 108 bits (271), Expect = 6e-23 Identities = 72/248 (29%), Positives = 112/248 (45%), Gaps = 4/248 (1%) Frame = +1 Query: 214 GEDIGR--FGKVFKGRCFGLEVAVKIPKVQELSPEQLE-KFKQEVAINSEINHPNVVRFL 384 GE IGR FG+VF GR V + +E P ++ KF QE I + +HPN+VR + Sbjct: 351 GEQIGRGNFGEVFSGRLRADNTLVAVKSCRETLPPDIKAKFLQEAKILKQYSHPNIVRLI 410 Query: 385 GACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLD 564 G C + +V E + L + +++ D GM Y+ + +H D Sbjct: 411 GVCTQKQPIYIVMELVQGGDFLTFLRTEGARLRMKTLLQMVGDAAAGMEYLESKCCIHRD 470 Query: 565 LKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPL-WMAPEMLLGKPFDEKADI 741 L N L+ KI+DFG++ D GG + P+ W APE L + ++D+ Sbjct: 471 LAARNCLVTEKNVLKISDFGMSREAADGIYAASGGLRQVPVKWTAPEALNYGRYSSESDV 530 Query: 742 YSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPA 921 +SFGI+LW+ + + V R P P+ + L+ +CW +P Sbjct: 531 WSFGILLWETFSLGASPYPNLSNQQTREFVE-KGGRLPCPELCPDAVFRLMEQCWAYEPG 589 Query: 922 LRPSFTEI 945 RPSF+ I Sbjct: 590 QRPSFSAI 597
>Q04736:YES_MOUSE Proto-oncogene tyrosine-protein kinase Yes - Mus musculus (Mouse)| Length = 541 Score = 108 bits (270), Expect = 7e-23 Identities = 85/266 (31%), Positives = 122/266 (45%), Gaps = 2/266 (0%) Frame = +1 Query: 160 EIPAEQLIIEEELSKDKDGEDIGRFGKVFKGRCFGL-EVAVKIPKVQELSPEQLEKFKQE 336 EIP E L +E +L + G FG+V+ G G +VA+K K + PE F QE Sbjct: 269 EIPRESLRLEVKLGQ-------GCFGEVWMGTWNGTTKVAIKTLKPGTMMPEA---FLQE 318 Query: 337 VAINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSN-KARPLSLARRMRIARD 513 I ++ H +V L A + +VTE + L L + + +A Sbjct: 319 AQIMKKLRHDKLVP-LYAVVSEEPIYIVTEFMSKGSLLDFLKEGDGKYLKLPQLVDMAAQ 377 Query: 514 IVKGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWM 693 I GM YI N +H DL+ N+L+ N KIADFGL + D + G K W Sbjct: 378 IADGMAYIERMNYIHRDLRAANILVGENLICKIADFGLARLIEDNEYTARQGAKFPIKWT 437 Query: 694 APEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTN 873 APE L F K+D++SFGI+ +L+T+ ++ V YR P PQG Sbjct: 438 APEAALYGRFTIKSDVWSFGILQTELVTKGRVPYPGMVNREVLEQVE-RGYRMPCPQGCP 496 Query: 874 QKLSYLIHRCWHPQPALRPSFTEIDN 951 + L L++ CW P RP+F I + Sbjct: 497 ESLHELMNLCWKKDPDERPTFEYIQS 522
>Q13308:PTK7_HUMAN Tyrosine-protein kinase-like 7 precursor - Homo sapiens (Human)| Length = 1070 Score = 108 bits (270), Expect = 7e-23 Identities = 71/255 (27%), Positives = 115/255 (45%), Gaps = 14/255 (5%) Frame = +1 Query: 232 FGKVFKGRCFGLEVAVK-----IPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGACL 396 FG+VF + GLE V + +Q +Q F++E+ + ++NH NVVR LG C Sbjct: 807 FGEVFLAKAQGLEEGVAETLVLVKSLQSKDEQQQLDFRRELEMFGKLNHANVVRLLGLCR 866 Query: 397 KPLNFRLVTEXXXXXXXXXXX--------SNKARPLSLARRMRIARDIVKGMIYIHAANL 552 + +V E K++PLS +++ + + GM ++ Sbjct: 867 EAEPHYMVLEYVDLGDLKQFLRISKSKDEKLKSQPLSTKQKVALCTQVALGMEHLSNNRF 926 Query: 553 VHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPL-WMAPEMLLGKPFDE 729 VH DL N L+ K++ GL+ + H PL WM+PE +L F Sbjct: 927 VHKDLAARNCLVSAQRQVKVSALGLSK-DVYNSEYYHFRQAWVPLRWMSPEAILEGDFST 985 Query: 730 KADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWH 909 K+D+++FG+++W++ T + + R P P+G KL L+ RCW Sbjct: 986 KSDVWAFGVLMWEVFTHGEMPHGGQADDEVLADLQAGKARLPQPEGCPSKLYRLMQRCWA 1045 Query: 910 PQPALRPSFTEIDNA 954 P RPSF+EI +A Sbjct: 1046 LSPKDRPSFSEIASA 1060
>P42683:LCK_CHICK Proto-oncogene tyrosine-protein kinase LCK - Gallus gallus| (Chicken) Length = 508 Score = 108 bits (270), Expect = 7e-23 Identities = 77/260 (29%), Positives = 120/260 (46%), Gaps = 1/260 (0%) Frame = +1 Query: 160 EIPAEQLIIEEELSKDKDGEDIGRFGKVFKGRCFG-LEVAVKIPKVQELSPEQLEKFKQE 336 E+P E L + E+L G+FG+V+ G G +VA+K K +SP F E Sbjct: 238 EVPRESLKLVEKLGA-------GQFGEVWMGFYNGHTKVAIKNLKQGSMSPSA---FLAE 287 Query: 337 VAINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDI 516 + + HP +VR K + + +++ LS+ + + +A I Sbjct: 288 ANLMKNLQHPRLVRLYAVVTKEPIYIITEYMEKGSLVDFLKTSEGIKLSINKLLDMAAQI 347 Query: 517 VKGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWMA 696 +GM +I A N +H DL+ N+L+ KIADFGL + D + G K W A Sbjct: 348 AEGMAFIEAKNYIHRDLRAANILVSEALCCKIADFGLARLIEDNEYTAREGAKFPIKWTA 407 Query: 697 PEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQ 876 PE + F K+D++SFGI+L +++T I+ + YR P P Q Sbjct: 408 PEAINYGTFTIKSDVWSFGILLTEIVTYGRIPYPGMTNPEVIQNLE-RGYRMPQPDNCPQ 466 Query: 877 KLSYLIHRCWHPQPALRPSF 936 +L L+ +CW QP RP+F Sbjct: 467 ELYELMMQCWKEQPEERPTF 486
>O70146:TESK1_MOUSE Dual specificity testis-specific protein kinase 1 - Mus musculus| (Mouse) Length = 627 Score = 108 bits (269), Expect = 1e-22 Identities = 87/306 (28%), Positives = 137/306 (44%), Gaps = 20/306 (6%) Frame = +1 Query: 88 PSAGPGTGAAIHDPFGVAKGFVGLEIPAEQLIIEEELSKDKDGEDI--------GRFGKV 243 P GPG G A + G A G G P+ + +S +D G F +V Sbjct: 7 PLRGPGPGEAPGEGPGGAGGGPGRGRPSSYRALRSAVSSLARVDDFDCAEKIGAGFFSEV 66 Query: 244 FK--GRCFGLEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGACLKPLNFRL 417 +K R G + +K+ K+ P +EV + + + HPN++RF+G C+ Sbjct: 67 YKVRHRQSGQVMVLKMNKL----PSNRSNTLREVQLMNRLRHPNILRFMGVCVHQGQLHA 122 Query: 418 VTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDLKPENVLL--- 588 +TE S+ PLS R+ +A DI +G+ Y+HA + H DL +N L+ Sbjct: 123 LTEYMNGGTLEQLLSSP-EPLSWPVRLHLALDIAQGLRYLHAKGVFHRDLTSKNCLVRRE 181 Query: 589 DFNGTAKIADFGLTVIRLDRQSLLHGGPK-------GTPLWMAPEMLLGKPFDEKADIYS 747 D TA + DFGL ++ + G + G+P WMAPE+L G+ +DEKAD+++ Sbjct: 182 DRGFTAVVGDFGLA----EKIPVYREGTRKEPLAVVGSPYWMAPEVLRGELYDEKADVFA 237 Query: 748 FGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPALR 927 FGI+L +L+ R + + +R + L C +P+ R Sbjct: 238 FGIVLCELIARVPADPDYLPRTEDF-GLDVPAFRTLVGNDCPLPFLLLAIHCCSMEPSTR 296 Query: 928 PSFTEI 945 FTEI Sbjct: 297 APFTEI 302
>P05480:SRC_MOUSE Neuronal proto-oncogene tyrosine-protein kinase Src - Mus musculus| (Mouse) Length = 541 Score = 108 bits (269), Expect = 1e-22 Identities = 90/307 (29%), Positives = 136/307 (44%), Gaps = 2/307 (0%) Frame = +1 Query: 67 YRCAAMQPSAGPGTGAAIHDPFGVAKGFVGLEIPAEQLIIEEELSKDKDGEDIGRFGKVF 246 +R + P++ P T D + EIP E L +E +L + G FG+V+ Sbjct: 247 HRLTTVCPTSKPQTQGLAKDAW---------EIPRESLRLEVKLGQ-------GCFGEVW 290 Query: 247 KGRCFGL-EVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGACLKPLNFRLVT 423 G G VA+K K +SPE F QE + ++ H +V+ L A + +VT Sbjct: 291 MGTWNGTTRVAIKTLKPGTMSPEA---FLQEAQVMKKLRHEKLVQ-LYAVVSEEPIYIVT 346 Query: 424 EXXXXXXXXXXXSNKA-RPLSLARRMRIARDIVKGMIYIHAANLVHLDLKPENVLLDFNG 600 E + + L L + + ++ I GM Y+ N VH DL+ N+L+ N Sbjct: 347 EYMNKGSLLDFLKGETGKYLRLPQLVDMSAQIASGMAYVERMNYVHRDLRAANILVGENL 406 Query: 601 TAKIADFGLTVIRLDRQSLLHGGPKGTPLWMAPEMLLGKPFDEKADIYSFGIILWQLLTR 780 K+ADFGL + D + G K W APE L F K+D++SFGI+L +L T+ Sbjct: 407 VCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTK 466 Query: 781 XXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPALRPSFTEIDNAYL 960 + V YR P P + L L+ +CW +P RP+F E A+L Sbjct: 467 GRVPYPGMVNREVLDQVE-RGYRMPCPPECPESLHDLMCQCWRKEPEERPTF-EYLQAFL 524 Query: 961 QPIIVET 981 + T Sbjct: 525 EDYFTST 531
>P53667:LIMK1_HUMAN LIM domain kinase 1 - Homo sapiens (Human)| Length = 647 Score = 108 bits (269), Expect = 1e-22 Identities = 72/264 (27%), Positives = 116/264 (43%), Gaps = 25/264 (9%) Frame = +1 Query: 235 GKVFKGRCFGLEVAV------KIPKVQEL---SPEQLEKFKQEVAINSEINHPNVVRFLG 387 G+V CFG + V ++ ++EL E F +EV + + HPNV++F+G Sbjct: 342 GEVLGKGCFGQAIKVTHRETGEVMVMKELIRFDEETQRTFLKEVKVMRCLEHPNVLKFIG 401 Query: 388 ACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDL 567 K +TE + ++R+ A+DI GM Y+H+ N++H DL Sbjct: 402 VLYKDKRLNFITEYIKGGTLRGIIKSMDSQYPWSQRVSFAKDIASGMAYLHSMNIIHRDL 461 Query: 568 KPENVLLDFNGTAKIADFGLTVIRLDRQSLLHG-------------GPKGTPLWMAPEML 708 N L+ N +ADFGL + +D ++ G G P WMAPEM+ Sbjct: 462 NSHNCLVRENKNVVVADFGLARLMVDEKTQPEGLRSLKKPDRKKRYTVVGNPYWMAPEMI 521 Query: 709 LGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVA---INNYRPPMPQGTNQK 879 G+ +DEK D++SFGI+L +++ R ++ Y PP Sbjct: 522 NGRSYDEKVDVFSFGIVLCEIIGRVNADPDYLPRTMDFGLNVRGFLDRYCPP---NCPPS 578 Query: 880 LSYLIHRCWHPQPALRPSFTEIDN 951 + RC P RPSF ++++ Sbjct: 579 FFPITVRCCDLDPEKRPSFVKLEH 602
>Q63572:TESK1_RAT Dual specificity testis-specific protein kinase 1 - Rattus norvegicus| (Rat) Length = 628 Score = 107 bits (268), Expect = 1e-22 Identities = 89/327 (27%), Positives = 146/327 (44%), Gaps = 20/327 (6%) Frame = +1 Query: 88 PSAGPGTGAAIHDPFGVAKGFVGLEIPAEQLIIEEELSKDKDGEDI--------GRFGKV 243 P GPG G + G A G G P+ + +S +D G F +V Sbjct: 7 PLRGPGPGETPVEGPGGAGGGPGRGRPSSYRALRSAVSSLARVDDFDCAEKIGAGFFSEV 66 Query: 244 FK--GRCFGLEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGACLKPLNFRL 417 +K R G + +K+ K+ P +EV + + + HPN++RF+G C+ Sbjct: 67 YKVRHRQSGQVMVLKMNKL----PSNRSNTLREVQLMNRLRHPNILRFMGVCVHQGQLHA 122 Query: 418 VTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDLKPENVLL--- 588 +TE S+ PLS R+ +A DI +G+ Y+HA + H DL +N L+ Sbjct: 123 LTEYMNGGTLEQLLSSP-EPLSWPVRLHLALDIAQGLRYLHAKGVFHRDLTSKNCLVRRE 181 Query: 589 DFNGTAKIADFGLTVIRLDRQSLLHGGPK-------GTPLWMAPEMLLGKPFDEKADIYS 747 D TA + DFGL ++ + G + G+P WMAPE+L G+ +DEKAD+++ Sbjct: 182 DGGFTAVVGDFGLA----EKIPVYREGARKEPLAVVGSPYWMAPEVLRGELYDEKADVFA 237 Query: 748 FGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPALR 927 FGI+L +L+ R + + +R + L C +P+ R Sbjct: 238 FGIVLCELIARVPADPDYLPRTEDF-GLDVPAFRTLVGNDCPLPFLLLAIHCCSMEPSAR 296 Query: 928 PSFTEIDNAYLQPIIVETAIPDEVGRV 1008 FTEI +L+ I+ + P + ++ Sbjct: 297 APFTEI-TQHLEQILEQLPEPTPLAKM 322
>P31693:SRC_RSVPA Tyrosine-protein kinase transforming protein Src - Rous sarcoma virus| (strain PA101T) Length = 523 Score = 107 bits (268), Expect = 1e-22 Identities = 78/276 (28%), Positives = 121/276 (43%), Gaps = 1/276 (0%) Frame = +1 Query: 160 EIPAEQLIIEEELSKDKDGEDIGRFGKVFKGRCFGL-EVAVKIPKVQELSPEQLEKFKQE 336 EIP E L +E +L + G FG+V+ G G VA+K K +SPE F QE Sbjct: 258 EIPRESLRLEVKLGQ-------GYFGEVWMGTWNGTTRVAIKTLKPGTMSPEA---FLQE 307 Query: 337 VAINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDI 516 + ++ H +V+ + + ++ + L L + + +A I Sbjct: 308 AQVMKKLRHEKLVQLYAMVSEEPIYIVIEYMSKGSLLDFLKGEMGKYLRLPQLVEMAAQI 367 Query: 517 VKGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWMA 696 GM Y+ N VH DL+ N+L+ N K+ADFGL + D + G + W A Sbjct: 368 ASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARPGARFPVKWTA 427 Query: 697 PEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQ 876 PE L F K+D++SFGI+L +L T+ + V YR P P + Sbjct: 428 PEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNGEVLDRVE-RGYRMPCPPECPE 486 Query: 877 KLSYLIHRCWHPQPALRPSFTEIDNAYLQPIIVETA 984 L L+ +CW P RP+F + L +++ A Sbjct: 487 SLHDLMCQCWRKDPEERPTFEYLQAQLLPACVLKIA 522
>Q9WUD9:SRC_RAT Proto-oncogene tyrosine-protein kinase Src - Rattus norvegicus (Rat)| Length = 536 Score = 107 bits (268), Expect = 1e-22 Identities = 90/307 (29%), Positives = 136/307 (44%), Gaps = 2/307 (0%) Frame = +1 Query: 67 YRCAAMQPSAGPGTGAAIHDPFGVAKGFVGLEIPAEQLIIEEELSKDKDGEDIGRFGKVF 246 +R + P++ P T D + EIP E L +E +L + G FG+V+ Sbjct: 242 HRLTTVCPTSKPQTQGLAKDAW---------EIPRESLRLEVKLGQ-------GCFGEVW 285 Query: 247 KGRCFGL-EVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGACLKPLNFRLVT 423 G G VA+K K +SPE F QE + ++ H +V+ L A + +VT Sbjct: 286 MGTWNGTTRVAIKTLKPGTMSPEA---FLQEAQVMKKLRHEKLVQ-LYAVVSEEPIYIVT 341 Query: 424 EXXXXXXXXXXXSNKA-RPLSLARRMRIARDIVKGMIYIHAANLVHLDLKPENVLLDFNG 600 E + + L L + + ++ I GM Y+ N VH DL+ N+L+ N Sbjct: 342 EYMNKGSLLDFLKGETGKYLRLPQLVDMSAQIASGMAYVDRMNYVHRDLRAANILVGENL 401 Query: 601 TAKIADFGLTVIRLDRQSLLHGGPKGTPLWMAPEMLLGKPFDEKADIYSFGIILWQLLTR 780 K+ADFGL + D + G K W APE L F K+D++SFGI+L +L T+ Sbjct: 402 VCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTK 461 Query: 781 XXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPALRPSFTEIDNAYL 960 + V YR P P + L L+ +CW +P RP+F E A+L Sbjct: 462 GRVPYPGMVNREVLDQVE-RGYRMPCPPECPESLHDLMCQCWRKEPEERPTF-EYLQAFL 519 Query: 961 QPIIVET 981 + T Sbjct: 520 EDYFTST 526
>P00523:SRC_CHICK Proto-oncogene tyrosine-protein kinase Src - Gallus gallus (Chicken)| Length = 533 Score = 107 bits (268), Expect = 1e-22 Identities = 86/276 (31%), Positives = 125/276 (45%), Gaps = 2/276 (0%) Frame = +1 Query: 160 EIPAEQLIIEEELSKDKDGEDIGRFGKVFKGRCFGL-EVAVKIPKVQELSPEQLEKFKQE 336 EIP E L +E +L + G FG+V+ G G VA+K K +SPE F QE Sbjct: 261 EIPRESLRLEVKLGQ-------GCFGEVWMGTWNGTTRVAIKTLKPGTMSPEA---FLQE 310 Query: 337 VAINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNK-ARPLSLARRMRIARD 513 + ++ H +V+ L A + +VTE + + L L + + +A Sbjct: 311 AQVMKKLRHEKLVQ-LYAVVSEEPIYIVTEYMSKGSLLDFLKGEMGKYLRLPQLVDMAAQ 369 Query: 514 IVKGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWM 693 I GM Y+ N VH DL+ N+L+ N K+ADFGL + D + G K W Sbjct: 370 IASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWT 429 Query: 694 APEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTN 873 APE L F K+D++SFGI+L +L T+ + V YR P P Sbjct: 430 APEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVE-RGYRMPCPPECP 488 Query: 874 QKLSYLIHRCWHPQPALRPSFTEIDNAYLQPIIVET 981 + L L+ +CW P RP+F E A+L+ T Sbjct: 489 ESLHDLMCQCWRKDPEERPTF-EYLQAFLEDYFTST 523
>Q91048:PTK7_CHICK Tyrosine-protein kinase-like 7 precursor - Gallus gallus (Chicken)| Length = 1051 Score = 107 bits (268), Expect = 1e-22 Identities = 71/254 (27%), Positives = 115/254 (45%), Gaps = 14/254 (5%) Frame = +1 Query: 226 GRFGKVFKGRCFGLE----VAVKIPKVQELSPEQLE-KFKQEVAINSEINHPNVVRFLGA 390 G FG+VF + G E A+ + K + EQL+ F++E + ++NH NVVR LG Sbjct: 786 GEFGEVFLAKAKGAEDAEGEALVLVKSLQTRDEQLQLDFRREAEMFGKLNHVNVVRLLGL 845 Query: 391 CLKPLNFRLVTEXXXXXXXXXXX--------SNKARPLSLARRMRIARDIVKGMIYIHAA 546 C + +V E S K +PLS ++ + + GM ++ Sbjct: 846 CREAEPHYMVLEYVDLGDLKQFLRISKSKDESLKPQPLSTKHKVSLCTQVALGMEHLSNG 905 Query: 547 NLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPL-WMAPEMLLGKPF 723 VH DL N L+ K++ L+ + H PL WM PE +L F Sbjct: 906 RFVHRDLAARNCLVSAQRQVKVSALSLSK-DVYNSEYYHFRQAWIPLRWMPPEAVLEDEF 964 Query: 724 DEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRC 903 K+D++SFG+++W++ T+ + + + P P+G +L+ L+ RC Sbjct: 965 STKSDVWSFGVLMWEVFTQGEMPYAPLADDEVLAGLKSGKTKLPQPEGCPSRLTKLMQRC 1024 Query: 904 WHPQPALRPSFTEI 945 W P P RPSF+E+ Sbjct: 1025 WAPSPKDRPSFSEL 1038
>Q8IVT5:KSR1_HUMAN Kinase suppressor of Ras 1 - Homo sapiens (Human)| Length = 921 Score = 107 bits (268), Expect = 1e-22 Identities = 73/220 (33%), Positives = 116/220 (52%), Gaps = 13/220 (5%) Frame = +1 Query: 160 EIPAEQLIIEEELSKDKDGEDIGRFGKVFKGRCFGLEVAVKIPKVQELSPEQLEKFKQEV 339 +IP EQ+ + E + + GR+G+V +GR G EVA+++ ++ + + L+ FK+EV Sbjct: 605 DIPFEQVELGEPIGQ-------GRWGRVHRGRWHG-EVAIRLLEMDGHNQDHLKLFKKEV 656 Query: 340 AINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIV 519 + H NVV F+GAC+ P + ++T + L + + +IA++I+ Sbjct: 657 MNYRQTRHENVVLFMGACMNPPHLAIITSFCKGRTLHSFVRDPKTSLDINKTRQIAQEII 716 Query: 520 KGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFGL----TVIRLDRQSLLHGGPKGTPL 687 KGM Y+HA +VH DLK +NV D NG I DFGL V+R R+ Sbjct: 717 KGMGYLHAKGIVHKDLKSKNVFYD-NGKVVITDFGLFGISGVVREGRRENQLKLSHDWLC 775 Query: 688 WMAP----EMLLGK-----PFDEKADIYSFGIILWQLLTR 780 ++AP EM GK PF + AD+Y+FG + ++L R Sbjct: 776 YLAPEIVREMTPGKDEDQLPFSKAADVYAFGTVWYELQAR 815
>P00543:FES_FSVST Tyrosine-protein kinase transforming protein Fes - Feline sarcoma| virus (strain Snyder-Theilen) Length = 477 Score = 107 bits (268), Expect = 1e-22 Identities = 71/246 (28%), Positives = 111/246 (45%), Gaps = 4/246 (1%) Frame = +1 Query: 214 GEDIGR--FGKVFKGRCFGLEVAVKIPKVQELSPEQLE-KFKQEVAINSEINHPNVVRFL 384 GE IGR FG+VF GR V + +E P ++ KF QE I + +HPN+VR + Sbjct: 219 GEQIGRGNFGEVFSGRLRADNTLVAVKSCRETLPPDIKAKFLQEAKILKQYSHPNIVRLI 278 Query: 385 GACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLD 564 G C + +V E + L + +++ D GM Y+ + +H D Sbjct: 279 GVCTQKQPIYIVMELVQGGDFLTFLRTEGARLRMKTLLQMVGDAAAGMEYLESKCCIHRD 338 Query: 565 LKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPL-WMAPEMLLGKPFDEKADI 741 L N L+ KI+DFG++ D GG + P+ W APE L + ++D+ Sbjct: 339 LAARNCLVTEKNVLKISDFGMSREEADGVYAASGGLRLVPVKWTAPEALNYGRYSSESDV 398 Query: 742 YSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPA 921 +SFGI+LW+ + + V R P P+ + L+ +CW +P Sbjct: 399 WSFGILLWETFSLGASPYPNLSNQQTREFVE-KGGRLPCPELCPDAVFRLMEQCWAYEPG 457 Query: 922 LRPSFT 939 RPSF+ Sbjct: 458 QRPSFS 463
>P10936:YES_XENLA Tyrosine-protein kinase Yes - Xenopus laevis (African clawed frog)| Length = 537 Score = 107 bits (267), Expect = 2e-22 Identities = 90/297 (30%), Positives = 129/297 (43%), Gaps = 2/297 (0%) Frame = +1 Query: 67 YRCAAMQPSAGPGTGAAIHDPFGVAKGFVGLEIPAEQLIIEEELSKDKDGEDIGRFGKVF 246 YR + PS P T D + EIP E L ++ +L + G FG+V+ Sbjct: 243 YRLTTVCPSVKPQTQGLAKDAW---------EIPRESLRLDVKLGQ-------GCFGEVW 286 Query: 247 KGRCFGL-EVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGACLKPLNFRLVT 423 G G +VA+K K + PE F QE I ++ H +V L A + +VT Sbjct: 287 IGTWNGTTKVAIKTLKPGTMMPEA---FLQEAQIMKKLRHDKLVP-LYAVVSEEPIYIVT 342 Query: 424 EXXXXXXXXXXXSN-KARPLSLARRMRIARDIVKGMIYIHAANLVHLDLKPENVLLDFNG 600 E + L L + + +A I GM YI N +H DL+ N+L+ N Sbjct: 343 EYMIKGSLLDFLKEGNGKYLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGDNL 402 Query: 601 TAKIADFGLTVIRLDRQSLLHGGPKGTPLWMAPEMLLGKPFDEKADIYSFGIILWQLLTR 780 KIADFGL + D + G K W APE L F K+D++SFGI+L +L+ + Sbjct: 403 VCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVAK 462 Query: 781 XXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPALRPSFTEIDN 951 ++ V YR P PQ + L L+ CW P RP+F I + Sbjct: 463 GRVPYPGMVNREVLEQVE-RGYRMPCPQRCPESLHELMKLCWKKDPDERPTFEYIQS 518
>P53669:LIMK1_RAT LIM domain kinase 1 - Rattus norvegicus (Rat)| Length = 647 Score = 107 bits (267), Expect = 2e-22 Identities = 74/263 (28%), Positives = 116/263 (44%), Gaps = 25/263 (9%) Frame = +1 Query: 235 GKVFKGRCFGLEVAV------KIPKVQEL---SPEQLEKFKQEVAINSEINHPNVVRFLG 387 G+V CFG + V ++ ++EL E F +EV + + HPNV++F+G Sbjct: 342 GEVLGKGCFGQAIKVTHRETGEVMVMKELIRFDEETQRTFLKEVKVMRCLEHPNVLKFIG 401 Query: 388 ACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDL 567 K +TE + ++R+ A+DI GM Y+H+ N++H DL Sbjct: 402 VLYKDKRLNFITEYIKGGTLRGIIKSMDSQYPWSQRVSFAKDIASGMAYLHSMNIIHRDL 461 Query: 568 KPENVLLDFNGTAKIADFGLTVIRLDRQ-------SLLHGGPK------GTPLWMAPEML 708 N L+ N +ADFGL + +D + SL K G P WMAPEM+ Sbjct: 462 NSHNCLVRENRNVVVADFGLARLMIDEKGQSEDLRSLKKPDRKKRYTVVGNPYWMAPEMI 521 Query: 709 LGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVA---INNYRPPMPQGTNQK 879 G+ +DEK D++SFGI+L +++ R ++ Y PP Sbjct: 522 NGRSYDEKVDVFSFGIVLCEIIGRVNADPDYLPRTMDFGLNVRGFLDRYCPP---NCPPS 578 Query: 880 LSYLIHRCWHPQPALRPSFTEID 948 + RC P RPSF +++ Sbjct: 579 FFPITVRCCDLDPEKRPSFVKLE 601
>P13406:FYN_XENLA Proto-oncogene tyrosine-protein kinase Fyn - Xenopus laevis (African| clawed frog) Length = 537 Score = 107 bits (267), Expect = 2e-22 Identities = 82/261 (31%), Positives = 120/261 (45%), Gaps = 2/261 (0%) Frame = +1 Query: 160 EIPAEQLIIEEELSKDKDGEDIGRFGKVFKGRCFG-LEVAVKIPKVQELSPEQLEKFKQE 336 EIP E L + + L G+FG+V+ G G +VA+K K +SPE F +E Sbjct: 265 EIPRESLQLIKRLGN-------GQFGEVWMGTWNGNTKVAIKTLKPGTMSPES---FLEE 314 Query: 337 VAINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSN-KARPLSLARRMRIARD 513 I ++ H +V+ L A + +VTE + + R L L + +A Sbjct: 315 AQIMKKLKHDKLVQ-LYAVVSEEPIYIVTEYMSKGSLLDFLKDGEGRALKLPNLVDMAAQ 373 Query: 514 IVKGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWM 693 + +GM YI N +H DL+ N+L+ KIADFGL + D + G K W Sbjct: 374 VARGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWT 433 Query: 694 APEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTN 873 APE L F K+D++SFGI+L +L+T+ ++ V YR P PQ Sbjct: 434 APEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVE-RGYRMPCPQDCP 492 Query: 874 QKLSYLIHRCWHPQPALRPSF 936 L L+ CW P RP+F Sbjct: 493 ISLHELMLNCWKKDPEERPTF 513
>P14085:SRC_AVIST Tyrosine-protein kinase transforming protein Src - Avian sarcoma| virus (strain S2) Length = 557 Score = 107 bits (266), Expect = 2e-22 Identities = 88/287 (30%), Positives = 128/287 (44%), Gaps = 2/287 (0%) Frame = +1 Query: 160 EIPAEQLIIEEELSKDKDGEDIGRFGKVFKGRCFGL-EVAVKIPKVQELSPEQLEKFKQE 336 EIP E L +E +L + G FG+V+ G G VA+K K +SPE F QE Sbjct: 261 EIPRESLRLEVKLGQ-------GCFGEVWMGTWNGTTRVAIKTLKPGTMSPEA---FLQE 310 Query: 337 VAINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNK-ARPLSLARRMRIARD 513 + ++ H +V+ L A + +VTE + + L L + + +A Sbjct: 311 AQVMKKLRHEKLVQ-LYAVVSEEPIYIVTEYMSKGSLLDFLKGEMGKYLRLPQLVDMAAQ 369 Query: 514 IVKGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWM 693 I GM Y+ N VH DL+ N+L+ N K+ADFGL + D + G K W Sbjct: 370 IASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWT 429 Query: 694 APEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTN 873 APE L F K+D++SFGI+L +L T+ + V YR P P Sbjct: 430 APEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVE-RGYRMPCPPECP 488 Query: 874 QKLSYLIHRCWHPQPALRPSFTEIDNAYLQPIIVETAIPDEVGRVLW 1014 + L L+ +CW P RP+F YLQ + D +G + W Sbjct: 489 ESLHDLMCQCWRKDPEERPTF-----EYLQAF-----LEDYLGILAW 525
>Q9Z2W1:STK25_MOUSE Serine/threonine-protein kinase 25 - Mus musculus (Mouse)| Length = 426 Score = 106 bits (265), Expect = 3e-22 Identities = 79/259 (30%), Positives = 125/259 (48%), Gaps = 7/259 (2%) Frame = +1 Query: 190 EELSKDKDGEDIGRFGKVFKGRCFGLE--VAVKIPKVQELSPEQLEKFKQEVAINSEINH 363 EEL D G FG+V+KG + VA+KI ++E + +++E +QE+ + S+ + Sbjct: 17 EELFTKLDRIGKGSFGEVYKGIDNHTKEVVAIKIIDLEE-AEDEIEDIQQEITVLSQCDS 75 Query: 364 PNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHA 543 P + R+ G+ LK ++ E K PL I R+I+KG+ Y+H+ Sbjct: 76 PYITRYFGSYLKSTKLWIIMEYLGGGSALDLL--KPGPLEETYIATILREILKGLDYLHS 133 Query: 544 ANLVHLDLKPENVLLDFNGTAKIADFG----LTVIRLDRQSLLHGGPKGTPLWMAPEMLL 711 +H D+K NVLL G K+ADFG LT ++ R + + GTP WMAPE++ Sbjct: 134 ERKIHRDIKAANVLLSEQGDVKMADFGVAGQLTDTQIKRNTFV-----GTPFWMAPEVIK 188 Query: 712 GKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQK-LSY 888 +D KADI+S GI + L + + + NN PP +G + K Sbjct: 189 QSAYDFKADIWSLGITAIE-LAKGEPPNSDLHPMRVLFLIPKNN--PPTLEGHHSKPFKE 245 Query: 889 LIHRCWHPQPALRPSFTEI 945 + C + P RP+ E+ Sbjct: 246 FVEACLNKDPRFRPTAKEL 264
>Q1HKZ5:M3K13_MOUSE Mitogen-activated protein kinase kinase kinase 13 - Mus musculus| (Mouse) Length = 959 Score = 106 bits (265), Expect = 3e-22 Identities = 70/239 (29%), Positives = 111/239 (46%) Frame = +1 Query: 226 GRFGKVFKGRCFGLEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGACLKPL 405 G G VF G+ EVA+K KV+E + ++ ++ + HPN++ F G C + Sbjct: 176 GAQGAVFLGKFRAEEVAIK--KVREQNETDIKHLRK-------LKHPNIIAFKGVCTQAP 226 Query: 406 NFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDLKPENVL 585 + ++ E R ++ + + I GM Y+H ++H DLK NVL Sbjct: 227 CYCIIMEYCAHGQLYEVL-RAGRKITPRLLVDWSTGIASGMNYLHLHKIIHRDLKSPNVL 285 Query: 586 LDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWMAPEMLLGKPFDEKADIYSFGIILW 765 + KI+DFG + D+ + + GT WMAPE++ +P EK DI+SFG++LW Sbjct: 286 VTHTDAVKISDFGTSKELSDKSTKMSFA--GTVAWMAPEVIRNEPVSEKVDIWSFGVVLW 343 Query: 766 QLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPALRPSFTE 942 +LLT I V N+ P+P L+ + W +P RPSF + Sbjct: 344 ELLT-GEIPYKDVDSSAIIWGVGSNSLHLPVPSTCPDGFKILMKQTWQSKPRNRPSFRQ 401
>O43283:M3K13_HUMAN Mitogen-activated protein kinase kinase kinase 13 - Homo sapiens| (Human) Length = 966 Score = 106 bits (265), Expect = 3e-22 Identities = 70/239 (29%), Positives = 111/239 (46%) Frame = +1 Query: 226 GRFGKVFKGRCFGLEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGACLKPL 405 G G VF G+ EVA+K KV+E + ++ ++ + HPN++ F G C + Sbjct: 177 GAQGAVFLGKFRAEEVAIK--KVREQNETDIKHLRK-------LKHPNIIAFKGVCTQAP 227 Query: 406 NFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDLKPENVL 585 + ++ E R ++ + + I GM Y+H ++H DLK NVL Sbjct: 228 CYCIIMEYCAHGQLYEVL-RAGRKITPRLLVDWSTGIASGMNYLHLHKIIHRDLKSPNVL 286 Query: 586 LDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWMAPEMLLGKPFDEKADIYSFGIILW 765 + KI+DFG + D+ + + GT WMAPE++ +P EK DI+SFG++LW Sbjct: 287 VTHTDAVKISDFGTSKELSDKSTKMSFA--GTVAWMAPEVIRNEPVSEKVDIWSFGVVLW 344 Query: 766 QLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPALRPSFTE 942 +LLT I V N+ P+P L+ + W +P RPSF + Sbjct: 345 ELLT-GEIPYKDVDSSAIIWGVGSNSLHLPVPSTCPDGFKILMKQTWQSKPRNRPSFRQ 402
>Q8QFP8:LIMK1_CHICK LIM domain kinase 1 - Gallus gallus (Chicken)| Length = 662 Score = 106 bits (265), Expect = 3e-22 Identities = 65/204 (31%), Positives = 101/204 (49%), Gaps = 22/204 (10%) Frame = +1 Query: 235 GKVFKGRCFGLEVAV------KIPKVQEL---SPEQLEKFKQEVAINSEINHPNVVRFLG 387 G+V CFG + V ++ ++EL E F +EV + + HPNV++F+G Sbjct: 349 GEVLGKGCFGQAIKVTHRETGEVMVMKELIRFDEETQRTFLKEVKVMRCLEHPNVLKFIG 408 Query: 388 ACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDL 567 K +TE + ++R+ A+DI GM Y+H+ N++H DL Sbjct: 409 VLYKEKRLNFITEYIKGGTLRGLIKSMDSHYPWSQRVSFAKDIAAGMAYLHSMNIIHRDL 468 Query: 568 KPENVLLDFNGTAKIADFGLTVIRLDR-------QSLLHGGPK------GTPLWMAPEML 708 N L+ N + +ADFGL + +D Q+L K G P WMAPEM+ Sbjct: 469 NSHNCLVRENKSVVVADFGLARLMVDEKNQPEHLQNLKKPDRKKRYTVVGNPYWMAPEMI 528 Query: 709 LGKPFDEKADIYSFGIILWQLLTR 780 G+ +DEK DI+SFGI+L +++ R Sbjct: 529 NGRSYDEKVDIFSFGIVLCEIIGR 552
>P09759:EPHB1_RAT Ephrin type-B receptor 1 precursor - Rattus norvegicus (Rat)| Length = 984 Score = 106 bits (265), Expect = 3e-22 Identities = 77/275 (28%), Positives = 120/275 (43%), Gaps = 18/275 (6%) Frame = +1 Query: 226 GRFGKVFKGRCF-----GLEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGA 390 G FG+V+KGR + VA+K K S +Q F E +I + +HPN++R G Sbjct: 628 GEFGEVYKGRLKLPGKREIYVAIKTLKAG-YSEKQRRDFLSEASIMGQFDHPNIIRLEGV 686 Query: 391 CLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDLK 570 K ++TE ++ + + + R I GM Y+ N VH DL Sbjct: 687 VTKSRPVMIITEFMENGALDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLA 746 Query: 571 PENVLLDFNGTAKIADFGLTVIRLDRQS----LLHGGPKGTPLWMAPEMLLGKPFDEKAD 738 N+L++ N K++DFGL+ D S G K W APE + + F +D Sbjct: 747 ARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVRWTAPEAIAYRKFTSASD 806 Query: 739 IYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQP 918 ++S+GI++W++++ I A+ +YR P P L L+ CW Sbjct: 807 VWSYGIVMWEVMSFGERPYWDMSNQDVINAIE-QDYRLPPPMDCPAALHQLMLDCWQKDR 865 Query: 919 ALRPSFTEIDN---------AYLQPIIVETAIPDE 996 RP F EI N A L+ + TA+P + Sbjct: 866 NSRPRFAEIVNTLDKMIRNPASLKTVATITAVPSQ 900
>Q8CBF3:EPHB1_MOUSE Ephrin type-B receptor 1 precursor - Mus musculus (Mouse)| Length = 984 Score = 106 bits (265), Expect = 3e-22 Identities = 77/275 (28%), Positives = 120/275 (43%), Gaps = 18/275 (6%) Frame = +1 Query: 226 GRFGKVFKGRCF-----GLEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGA 390 G FG+V+KGR + VA+K K S +Q F E +I + +HPN++R G Sbjct: 628 GEFGEVYKGRLKLPGKREIYVAIKTLKAG-YSEKQRRDFLSEASIMGQFDHPNIIRLEGV 686 Query: 391 CLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDLK 570 K ++TE ++ + + + R I GM Y+ N VH DL Sbjct: 687 VTKSRPVMIITEFMENGALDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLA 746 Query: 571 PENVLLDFNGTAKIADFGLTVIRLDRQS----LLHGGPKGTPLWMAPEMLLGKPFDEKAD 738 N+L++ N K++DFGL+ D S G K W APE + + F +D Sbjct: 747 ARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVRWTAPEAIAYRKFTSASD 806 Query: 739 IYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQP 918 ++S+GI++W++++ I A+ +YR P P L L+ CW Sbjct: 807 VWSYGIVMWEVMSFGERPYWDMSNQDVINAIE-QDYRLPPPMDCPAALHQLMLDCWQKDR 865 Query: 919 ALRPSFTEIDN---------AYLQPIIVETAIPDE 996 RP F EI N A L+ + TA+P + Sbjct: 866 NSRPRFAEIVNTLDKMIRNPASLKTVATITAVPSQ 900
>P41242:MATK_MOUSE Megakaryocyte-associated tyrosine-protein kinase - Mus musculus| (Mouse) Length = 505 Score = 106 bits (264), Expect = 4e-22 Identities = 73/241 (30%), Positives = 114/241 (47%), Gaps = 1/241 (0%) Frame = +1 Query: 226 GRFGKVFKGRCFGLEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGACLKPL 405 G FG V +G G +VAVK K + + F E A+ +++ H N+VR LG L Sbjct: 242 GEFGAVLQGEYLGQKVAVKNIKCDVTA----QAFLDETAVMTKLQHRNLVRLLGVILHH- 296 Query: 406 NFRLVTEXXXXXXXXXXXSNKARPL-SLARRMRIARDIVKGMIYIHAANLVHLDLKPENV 582 +V E + R L S ++ ++ A + +GM Y+ + LVH DL N+ Sbjct: 297 GLYIVMEHVSKGNLVNFLRTRGRALVSTSQLLQFALHVAEGMEYLESKKLVHRDLAARNI 356 Query: 583 LLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWMAPEMLLGKPFDEKADIYSFGIIL 762 L+ + AK++DFGL + +R+ L + W APE L F K+D++SFG++L Sbjct: 357 LVSEDLVAKVSDFGLA--KAERKGL--DSSRLPVKWTAPEALKNGRFSSKSDVWSFGVLL 412 Query: 763 WQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPALRPSFTE 942 W++ + +AV YR P G + L+ CW +PA RP F + Sbjct: 413 WEVFSYGRAPYPKMSLKEVSEAVE-KGYRMEPPDGCPGSVHTLMGSCWEAEPARRPPFRK 471 Query: 943 I 945 I Sbjct: 472 I 472 Score = 39.7 bits (91), Expect = 0.043 Identities = 21/58 (36%), Positives = 29/58 (50%) Frame = +1 Query: 1417 PWFYGDLDKDAAFELLRNKQPGTFLVRFSSNPEHVGFVISVVDHKNTVVHIRVKHNAG 1590 PWF+G + A + L+ + G FLVR S+ H G + V V+H RV H G Sbjct: 119 PWFHGKISGQEAIQQLQPPEDGLFLVRESA--RHPGDYVLCVSFGRDVIHYRVLHRDG 174
>Q62844:FYN_RAT Proto-oncogene tyrosine-protein kinase Fyn - Rattus norvegicus (Rat)| Length = 537 Score = 106 bits (264), Expect = 4e-22 Identities = 82/261 (31%), Positives = 119/261 (45%), Gaps = 2/261 (0%) Frame = +1 Query: 160 EIPAEQLIIEEELSKDKDGEDIGRFGKVFKGRCFG-LEVAVKIPKVQELSPEQLEKFKQE 336 EIP E L + + L G+FG+V+ G G +VA+K K +SPE F +E Sbjct: 265 EIPRESLQLIKRLGN-------GQFGEVWMGTWNGNTKVAIKTLKPGTMSPES---FLEE 314 Query: 337 VAINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSN-KARPLSLARRMRIARD 513 I ++ H +V+ L A + +VTE + + R L L + +A Sbjct: 315 AQIMKKLKHDKLVQ-LYAVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQ 373 Query: 514 IVKGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWM 693 + GM YI N +H DL+ N+L+ KIADFGL + D + G K W Sbjct: 374 VAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWT 433 Query: 694 APEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTN 873 APE L F K+D++SFGI+L +L+T+ ++ V YR P PQ Sbjct: 434 APEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVE-RGYRMPCPQDCP 492 Query: 874 QKLSYLIHRCWHPQPALRPSF 936 L L+ CW P RP+F Sbjct: 493 ISLHELMIHCWKKDPEERPTF 513
>A1Y2K1:FYN_PIG Proto-oncogene tyrosine-protein kinase Fyn - Sus scrofa (Pig)| Length = 537 Score = 106 bits (264), Expect = 4e-22 Identities = 82/261 (31%), Positives = 119/261 (45%), Gaps = 2/261 (0%) Frame = +1 Query: 160 EIPAEQLIIEEELSKDKDGEDIGRFGKVFKGRCFG-LEVAVKIPKVQELSPEQLEKFKQE 336 EIP E L + + L G+FG+V+ G G +VA+K K +SPE F +E Sbjct: 265 EIPRESLQLIKRLGN-------GQFGEVWMGTWNGNTKVAIKTLKPGTMSPES---FLEE 314 Query: 337 VAINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSN-KARPLSLARRMRIARD 513 I ++ H +V+ L A + +VTE + + R L L + +A Sbjct: 315 AQIMKKLKHDKLVQ-LYAVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQ 373 Query: 514 IVKGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWM 693 + GM YI N +H DL+ N+L+ KIADFGL + D + G K W Sbjct: 374 VAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWT 433 Query: 694 APEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTN 873 APE L F K+D++SFGI+L +L+T+ ++ V YR P PQ Sbjct: 434 APEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVE-RGYRMPCPQDCP 492 Query: 874 QKLSYLIHRCWHPQPALRPSF 936 L L+ CW P RP+F Sbjct: 493 ISLHELMIHCWKKDPEERPTF 513
>P06241:FYN_HUMAN Proto-oncogene tyrosine-protein kinase Fyn - Homo sapiens (Human)| Length = 537 Score = 106 bits (264), Expect = 4e-22 Identities = 82/261 (31%), Positives = 119/261 (45%), Gaps = 2/261 (0%) Frame = +1 Query: 160 EIPAEQLIIEEELSKDKDGEDIGRFGKVFKGRCFG-LEVAVKIPKVQELSPEQLEKFKQE 336 EIP E L + + L G+FG+V+ G G +VA+K K +SPE F +E Sbjct: 265 EIPRESLQLIKRLGN-------GQFGEVWMGTWNGNTKVAIKTLKPGTMSPES---FLEE 314 Query: 337 VAINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSN-KARPLSLARRMRIARD 513 I ++ H +V+ L A + +VTE + + R L L + +A Sbjct: 315 AQIMKKLKHDKLVQ-LYAVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQ 373 Query: 514 IVKGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWM 693 + GM YI N +H DL+ N+L+ KIADFGL + D + G K W Sbjct: 374 VAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWT 433 Query: 694 APEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTN 873 APE L F K+D++SFGI+L +L+T+ ++ V YR P PQ Sbjct: 434 APEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVE-RGYRMPCPQDCP 492 Query: 874 QKLSYLIHRCWHPQPALRPSF 936 L L+ CW P RP+F Sbjct: 493 ISLHELMIHCWKKDPEERPTF 513
>A0JNB0:FYN_BOVIN Proto-oncogene tyrosine-protein kinase Fyn - Bos taurus (Bovine)| Length = 537 Score = 106 bits (264), Expect = 4e-22 Identities = 82/261 (31%), Positives = 119/261 (45%), Gaps = 2/261 (0%) Frame = +1 Query: 160 EIPAEQLIIEEELSKDKDGEDIGRFGKVFKGRCFG-LEVAVKIPKVQELSPEQLEKFKQE 336 EIP E L + + L G+FG+V+ G G +VA+K K +SPE F +E Sbjct: 265 EIPRESLQLIKRLGN-------GQFGEVWMGTWNGNTKVAIKTLKPGTMSPES---FLEE 314 Query: 337 VAINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSN-KARPLSLARRMRIARD 513 I ++ H +V+ L A + +VTE + + R L L + +A Sbjct: 315 AQIMKKLKHDKLVQ-LYAVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQ 373 Query: 514 IVKGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWM 693 + GM YI N +H DL+ N+L+ KIADFGL + D + G K W Sbjct: 374 VAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWT 433 Query: 694 APEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTN 873 APE L F K+D++SFGI+L +L+T+ ++ V YR P PQ Sbjct: 434 APEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVE-RGYRMPCPQDCP 492 Query: 874 QKLSYLIHRCWHPQPALRPSF 936 L L+ CW P RP+F Sbjct: 493 ISLHELMIHCWKKDPEERPTF 513
>P54762:EPHB1_HUMAN Ephrin type-B receptor 1 precursor - Homo sapiens (Human)| Length = 984 Score = 106 bits (264), Expect = 4e-22 Identities = 77/275 (28%), Positives = 120/275 (43%), Gaps = 18/275 (6%) Frame = +1 Query: 226 GRFGKVFKGRCF-----GLEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGA 390 G FG+V+KGR + VA+K K S +Q F E +I + +HPN++R G Sbjct: 628 GEFGEVYKGRLKLPGKREIYVAIKTLKAG-YSEKQRRDFLSEASIMGQFDHPNIIRLEGV 686 Query: 391 CLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDLK 570 K ++TE ++ + + + R I GM Y+ N VH DL Sbjct: 687 VTKSRPVMIITEFMENGALDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLAEMNYVHRDLA 746 Query: 571 PENVLLDFNGTAKIADFGLTVIRLDRQS----LLHGGPKGTPLWMAPEMLLGKPFDEKAD 738 N+L++ N K++DFGL+ D S G K W APE + + F +D Sbjct: 747 ARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVRWTAPEAIAYRKFTSASD 806 Query: 739 IYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQP 918 ++S+GI++W++++ I A+ +YR P P L L+ CW Sbjct: 807 VWSYGIVMWEVMSFGERPYWDMSNQDVINAIE-QDYRLPPPMDCPAALHQLMLDCWQKDR 865 Query: 919 ALRPSFTEIDN---------AYLQPIIVETAIPDE 996 RP F EI N A L+ + TA+P + Sbjct: 866 NSRPRFAEIVNTLDKMIRNPASLKTVATITAVPSQ 900
>Q02977:YRK_CHICK Proto-oncogene tyrosine-protein kinase Yrk - Gallus gallus (Chicken)| Length = 536 Score = 105 bits (263), Expect = 5e-22 Identities = 83/261 (31%), Positives = 121/261 (46%), Gaps = 2/261 (0%) Frame = +1 Query: 160 EIPAEQLIIEEELSKDKDGEDIGRFGKVFKGRCFGL-EVAVKIPKVQELSPEQLEKFKQE 336 EIP E L + ++L G+FG+V+ G G +VAVK K +SPE F +E Sbjct: 264 EIPRESLQLLQKLGN-------GQFGEVWMGTWNGTTKVAVKTLKPGTMSPEA---FLEE 313 Query: 337 VAINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSN-KARPLSLARRMRIARD 513 I + H +V+ L A + +VTE + R L L + + +A Sbjct: 314 AQIMKRLRHDKLVQ-LYAVVSEEPIYIVTEFMSQGSLLDFLKDGDGRYLKLPQLVDMAAQ 372 Query: 514 IVKGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWM 693 I GM YI N +H DL+ N+L+ N KIADFGL + D + G K W Sbjct: 373 IAAGMAYIERMNYIHRDLRAANILVGDNLVCKIADFGLARLIEDNEYTARQGAKFPIKWT 432 Query: 694 APEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTN 873 APE L F K+D++SFGI+L +L+T+ ++ V YR P G Sbjct: 433 APEAALFGKFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVE-RGYRMQCPGGCP 491 Query: 874 QKLSYLIHRCWHPQPALRPSF 936 L ++ +CW +P RP+F Sbjct: 492 PSLHDVMVQCWKREPEERPTF 512
>Q00PJ8:MET_ATEAB Hepatocyte growth factor receptor precursor - Atelerix albiventris| (Middle-African hedgehog) Length = 1382 Score = 105 bits (263), Expect = 5e-22 Identities = 74/250 (29%), Positives = 115/250 (46%), Gaps = 10/250 (4%) Frame = +1 Query: 226 GRFGKVFKGRCFG-----LEVAVK-IPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLG 387 G FG V+ G + AVK + ++ ++ ++ +F E I + +HPNV+ LG Sbjct: 1088 GHFGCVYHGTLLDNDDKKIHCAVKSLNRITDIG--EVSQFLTEGIIMKDFSHPNVLSLLG 1145 Query: 388 ACLKPLNFRLVT-EXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLD 564 CL+ LV N+ ++ + + KGM Y+ + VH D Sbjct: 1146 ICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRD 1205 Query: 565 LKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPL---WMAPEMLLGKPFDEKA 735 L N +LD N T K+ADFGL D++ G L WMA E L + F K+ Sbjct: 1206 LAARNCMLDENFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKS 1265 Query: 736 DIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQ 915 D++SFG++LW+L+TR I + R P+ L ++ +CWHP+ Sbjct: 1266 DVWSFGVLLWELMTR-GAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPK 1324 Query: 916 PALRPSFTEI 945 LRPSF+E+ Sbjct: 1325 AELRPSFSEL 1334
>P39688:FYN_MOUSE Proto-oncogene tyrosine-protein kinase Fyn - Mus musculus (Mouse)| Length = 537 Score = 105 bits (263), Expect = 5e-22 Identities = 82/261 (31%), Positives = 119/261 (45%), Gaps = 2/261 (0%) Frame = +1 Query: 160 EIPAEQLIIEEELSKDKDGEDIGRFGKVFKGRCFG-LEVAVKIPKVQELSPEQLEKFKQE 336 EIP E L + + L G+FG+V+ G G +VA+K K +SPE F +E Sbjct: 265 EIPRESLQLIKRLGN-------GQFGEVWLGTWNGNTKVAIKTLKPGTMSPES---FLEE 314 Query: 337 VAINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSN-KARPLSLARRMRIARD 513 I ++ H +V+ L A + +VTE + + R L L + +A Sbjct: 315 AQIMKKLKHDKLVQ-LYAVVSEEPIYIVTEYMSKGSLLDFLKDGEGRALKLPNLVDMAAQ 373 Query: 514 IVKGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWM 693 + GM YI N +H DL+ N+L+ KIADFGL + D + G K W Sbjct: 374 VAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWT 433 Query: 694 APEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTN 873 APE L F K+D++SFGI+L +L+T+ ++ V YR P PQ Sbjct: 434 APEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVE-RGYRMPCPQDCP 492 Query: 874 QKLSYLIHRCWHPQPALRPSF 936 L L+ CW P RP+F Sbjct: 493 ISLHELMIHCWKKDPEERPTF 513
>O00506:STK25_HUMAN Serine/threonine-protein kinase 25 - Homo sapiens (Human)| Length = 426 Score = 105 bits (262), Expect = 6e-22 Identities = 78/259 (30%), Positives = 125/259 (48%), Gaps = 7/259 (2%) Frame = +1 Query: 190 EELSKDKDGEDIGRFGKVFKGRCFGLE--VAVKIPKVQELSPEQLEKFKQEVAINSEINH 363 EEL D G FG+V+KG + VA+KI ++E + +++E +QE+ + S+ + Sbjct: 17 EELFTKLDRIGKGSFGEVYKGIDNHTKEVVAIKIIDLEE-AEDEIEDIQQEITVLSQCDS 75 Query: 364 PNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHA 543 P + R+ G+ LK ++ E K PL I R+I+KG+ Y+H+ Sbjct: 76 PYITRYFGSYLKSTKLWIIMEYLGGGSALDLL--KPGPLEETYIATILREILKGLDYLHS 133 Query: 544 ANLVHLDLKPENVLLDFNGTAKIADFG----LTVIRLDRQSLLHGGPKGTPLWMAPEMLL 711 +H D+K NVLL G K+ADFG LT ++ R + + GTP WMAPE++ Sbjct: 134 ERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFV-----GTPFWMAPEVIK 188 Query: 712 GKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQK-LSY 888 +D KADI+S GI + L + + + N+ PP +G + K Sbjct: 189 QSAYDFKADIWSLGITAIE-LAKGEPPNSDLHPMRVLFLIPKNS--PPTLEGQHSKPFKE 245 Query: 889 LIHRCWHPQPALRPSFTEI 945 + C + P RP+ E+ Sbjct: 246 FVEACLNKDPRFRPTAKEL 264
>Q2QLH6:MET_OTOGA Hepatocyte growth factor receptor precursor - Otolemur garnettii| (Small-eared galago) (Garnett's greater bushbaby) Length = 1382 Score = 105 bits (262), Expect = 6e-22 Identities = 71/248 (28%), Positives = 113/248 (45%), Gaps = 8/248 (3%) Frame = +1 Query: 226 GRFGKVFKGRCF---GLEVAVKIPKVQELSP-EQLEKFKQEVAINSEINHPNVVRFLGAC 393 G FG V+ G G ++ + + ++ ++ +F E I + +HPNV+ LG C Sbjct: 1088 GHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGIC 1147 Query: 394 LKPLNFRLVT-EXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDLK 570 L+ LV N+ ++ + + KGM Y+ + VH DL Sbjct: 1148 LRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLA 1207 Query: 571 PENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPL---WMAPEMLLGKPFDEKADI 741 N +LD N T K+ADFGL D++ G L WMA E L + F K+D+ Sbjct: 1208 ARNCMLDENFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDV 1267 Query: 742 YSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPA 921 +SFG++LW+L+TR I + R P+ L ++ +CWHP+ Sbjct: 1268 WSFGVLLWELMTR-GAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAE 1326 Query: 922 LRPSFTEI 945 +RPSF+E+ Sbjct: 1327 MRPSFSEL 1334
>P16056:MET_MOUSE Hepatocyte growth factor receptor precursor - Mus musculus (Mouse)| Length = 1379 Score = 105 bits (262), Expect = 6e-22 Identities = 71/248 (28%), Positives = 113/248 (45%), Gaps = 8/248 (3%) Frame = +1 Query: 226 GRFGKVFKGRCF---GLEVAVKIPKVQELSP-EQLEKFKQEVAINSEINHPNVVRFLGAC 393 G FG V+ G G ++ + + ++ E++ +F E I + +HPNV+ LG C Sbjct: 1085 GHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIEEVSQFLTEGIIMKDFSHPNVLSLLGIC 1144 Query: 394 LKPLNFRLVT-EXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDLK 570 L+ LV N+ ++ + + KGM Y+ + VH DL Sbjct: 1145 LRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLA 1204 Query: 571 PENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPL---WMAPEMLLGKPFDEKADI 741 N +LD T K+ADFGL D++ G L WMA E L + F K+D+ Sbjct: 1205 ARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDV 1264 Query: 742 YSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPA 921 +SFG++LW+L+TR I + R P+ L ++ +CWHP+ Sbjct: 1265 WSFGVLLWELMTR-GAPPYPDVNTFDITIYLLQGRRLLQPEYCPDALYEVMLKCWHPKAE 1323 Query: 922 LRPSFTEI 945 +RPSF+E+ Sbjct: 1324 MRPSFSEL 1331
>Q5R8X7:M3K13_PONPY Mitogen-activated protein kinase kinase kinase 13 - Pongo pygmaeus| (Orangutan) Length = 966 Score = 105 bits (262), Expect = 6e-22 Identities = 69/239 (28%), Positives = 111/239 (46%) Frame = +1 Query: 226 GRFGKVFKGRCFGLEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGACLKPL 405 G G VF G+ EVA+K KV+E + ++ ++ + HPN++ F G C + Sbjct: 177 GAQGAVFLGKFRAEEVAIK--KVREQNETDIKHLRK-------LKHPNIIAFKGVCTQAP 227 Query: 406 NFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDLKPENVL 585 + ++ E R ++ + + I GM Y+H ++H DLK NVL Sbjct: 228 CYCIIMEYCAHGQLYEVL-RAGRKITPRLLVDWSTGIASGMNYLHLHKIIHRDLKSPNVL 286 Query: 586 LDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWMAPEMLLGKPFDEKADIYSFGIILW 765 + KI+DFG + D+ + + GT W+APE++ +P EK DI+SFG++LW Sbjct: 287 VTHTDAVKISDFGTSKELSDKSTKMSFA--GTVAWLAPEVIRNEPVSEKVDIWSFGVVLW 344 Query: 766 QLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPALRPSFTE 942 +LLT I V N+ P+P L+ + W +P RPSF + Sbjct: 345 ELLT-GEIPYKDVDSSAIIWGVGSNSLHLPVPSTCPDGFKILMKQTWQSKPRNRPSFRQ 402
>Q8JH64:BTK_CHICK Tyrosine-protein kinase BTK - Gallus gallus (Chicken)| Length = 657 Score = 105 bits (262), Expect = 6e-22 Identities = 69/274 (25%), Positives = 123/274 (44%), Gaps = 1/274 (0%) Frame = +1 Query: 127 PFGVAKGFVGLEIPAEQLIIEEELSKDKDGEDIGRFGKVFKGRCFG-LEVAVKIPKVQEL 303 P G+ EI + L +EL G+FG V G+ G VA+K+ + + Sbjct: 383 PSTAGLGYGSWEIDPKDLTFLKELGT-------GQFGVVKYGKWRGQYNVAIKMIREGSM 435 Query: 304 SPEQLEKFKQEVAINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNKARPLS 483 S ++ F E + ++H +V+ G C K ++TE R Sbjct: 436 SEDE---FIDEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNFLRETQRRFQ 492 Query: 484 LARRMRIARDIVKGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLH 663 A + + +D+ + M Y+ + +H DL N L++ G K++DFGL+ LD + Sbjct: 493 PAELLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGIVKVSDFGLSRYVLDDEYTSS 552 Query: 664 GGPKGTPLWMAPEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINN 843 G K W PE+LL F K+D++SFG+++W++ + + V I Sbjct: 553 MGSKFPVRWSPPEVLLYSKFSSKSDVWSFGVLMWEVYSLGKMPYERFNNSETTEHV-IQG 611 Query: 844 YRPPMPQGTNQKLSYLIHRCWHPQPALRPSFTEI 945 R PQ ++++ +++ CWH + RP+F+ + Sbjct: 612 LRLYRPQQASERVYAIMYSCWHEKAEERPTFSAL 645
>P42682:TXK_MOUSE Tyrosine-protein kinase TXK - Mus musculus (Mouse)| Length = 527 Score = 105 bits (261), Expect = 8e-22 Identities = 64/242 (26%), Positives = 111/242 (45%), Gaps = 2/242 (0%) Frame = +1 Query: 226 GRFGKVFKGRCFGLEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGACLKPL 405 G+FG V G + + V I + E S + E F +E + +++H +V+ G C++ Sbjct: 280 GQFGVVHLGE-WRAHIPVAIKAINEGSMSE-EDFIEEAKVMMKLSHSRLVQLYGVCIQQK 337 Query: 406 NFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDLKPENVL 585 +VTE + L A + + +DI +GM Y+ + +H DL N L Sbjct: 338 PLYIVTEFMENGCLLDYLRERKGQLQKALLLSMCQDICEGMAYLERSCYIHRDLAARNCL 397 Query: 586 LDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWMAPEMLLGKPFDEKADIYSFGIILW 765 + KI+DFG+ LD + + G K W PE+ + K+D++SFG+++W Sbjct: 398 VSSACVVKISDFGMARYVLDDEYISSSGAKFPVKWCPPEVFHFNKYSSKSDVWSFGVLMW 457 Query: 766 QLLTRXXXXXXXXXXXXXIKAVA--INNYRPPMPQGTNQKLSYLIHRCWHPQPALRPSFT 939 ++ T ++A++ YRP + T ++ Y CWH P RP+F Sbjct: 458 EVFTEGKMPFENKSNLQVVEAISQGFRLYRPHLAPMTIYRVMY---SCWHESPKGRPTFA 514 Query: 940 EI 945 E+ Sbjct: 515 EL 516
>Q3SWY6:STK25_BOVIN Serine/threonine-protein kinase 25 - Bos taurus (Bovine)| Length = 426 Score = 105 bits (261), Expect = 8e-22 Identities = 78/259 (30%), Positives = 125/259 (48%), Gaps = 7/259 (2%) Frame = +1 Query: 190 EELSKDKDGEDIGRFGKVFKGRCFGLE--VAVKIPKVQELSPEQLEKFKQEVAINSEINH 363 EEL D G FG+V+KG + VA+KI ++E + +++E +QE+ + S+ + Sbjct: 17 EELFTKLDRIGKGSFGEVYKGIDNRTKEVVAIKIIDLEE-AEDEIEDIQQEITVLSQCDS 75 Query: 364 PNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHA 543 P + R+ G+ LK ++ E K PL I R+I+KG+ Y+H+ Sbjct: 76 PYITRYFGSYLKSTKLWIIMEYLGGGSALDLL--KPGPLEETYIATILREILKGLDYLHS 133 Query: 544 ANLVHLDLKPENVLLDFNGTAKIADFG----LTVIRLDRQSLLHGGPKGTPLWMAPEMLL 711 +H D+K NVLL G K+ADFG LT ++ R + + GTP WMAPE++ Sbjct: 134 ERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFV-----GTPFWMAPEVIK 188 Query: 712 GKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQK-LSY 888 +D KADI+S GI + L + + + N+ PP +G + K Sbjct: 189 QSAYDFKADIWSLGITAIE-LAKGEPPNSDLHPMRVLFLIPKNS--PPTLEGHHSKPFKE 245 Query: 889 LIHRCWHPQPALRPSFTEI 945 + C + P RP+ E+ Sbjct: 246 FVEACLNKDPRFRPTAKEL 264
>P42679:MATK_HUMAN Megakaryocyte-associated tyrosine-protein kinase - Homo sapiens| (Human) Length = 507 Score = 105 bits (261), Expect = 8e-22 Identities = 71/241 (29%), Positives = 115/241 (47%), Gaps = 1/241 (0%) Frame = +1 Query: 226 GRFGKVFKGRCFGLEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGACLKPL 405 G FG V +G G +VAVK K + + F E A+ +++ H N+VR LG L Sbjct: 244 GEFGAVLQGEYLGQKVAVKNIKCDVTA----QAFLDETAVMTKMQHENLVRLLGVILHQ- 298 Query: 406 NFRLVTEXXXXXXXXXXXSNKARPL-SLARRMRIARDIVKGMIYIHAANLVHLDLKPENV 582 +V E + R L + A+ ++ + + +GM Y+ + LVH DL N+ Sbjct: 299 GLYIVMEHVSKGNLVNFLRTRGRALVNTAQLLQFSLHVAEGMEYLESKKLVHRDLAARNI 358 Query: 583 LLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWMAPEMLLGKPFDEKADIYSFGIIL 762 L+ + AK++DFGL + +R+ L + W APE L F K+D++SFG++L Sbjct: 359 LVSEDLVAKVSDFGLA--KAERKGL--DSSRLPVKWTAPEALKHGKFTSKSDVWSFGVLL 414 Query: 763 WQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPALRPSFTE 942 W++ + +AV YR P+G + L+ CW +PA RP F + Sbjct: 415 WEVFSYGRAPYPKMSLKEVSEAVE-KGYRMEPPEGCPGPVHVLMSSCWEAEPARRPPFRK 473 Query: 943 I 945 + Sbjct: 474 L 474 Score = 39.3 bits (90), Expect = 0.056 Identities = 21/58 (36%), Positives = 29/58 (50%) Frame = +1 Query: 1417 PWFYGDLDKDAAFELLRNKQPGTFLVRFSSNPEHVGFVISVVDHKNTVVHIRVKHNAG 1590 PWF+G + A + L+ + G FLVR S+ H G + V V+H RV H G Sbjct: 121 PWFHGKISGQEAVQQLQPPEDGLFLVRESA--RHPGDYVLCVSFGRDVIHYRVLHRDG 176
>P42685:FRK_HUMAN Tyrosine-protein kinase FRK - Homo sapiens (Human)| Length = 505 Score = 105 bits (261), Expect = 8e-22 Identities = 68/242 (28%), Positives = 113/242 (46%), Gaps = 5/242 (2%) Frame = +1 Query: 226 GRFGKVFKGRCFGLE-VAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGACLKP 402 G+FG+V++G VAVK K + P F +E I + HP +++ C Sbjct: 243 GQFGEVWEGLWNNTTPVAVKTLKPGSMDPND---FLREAQIMKNLRHPKLIQLYAVCTLE 299 Query: 403 LNFRLVTEXXXXXXXXXXXSNKA-RPLSLARRMRIARDIVKGMIYIHAANLVHLDLKPEN 579 ++TE N + L +++ +A + GM Y+ + N +H DL N Sbjct: 300 DPIYIITELMRHGSLQEYLQNDTGSKIHLTQQVDMAAQVASGMAYLESRNYIHRDLAARN 359 Query: 580 VLLDFNGTAKIADFGLT-VIRLDRQSLLHGGP--KGTPLWMAPEMLLGKPFDEKADIYSF 750 VL+ + K+ADFGL V ++D + + K W APE + F K+D++SF Sbjct: 360 VLVGEHNIYKVADFGLARVFKVDNEDIYESRHEIKLPVKWTAPEAIRSNKFSIKSDVWSF 419 Query: 751 GIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPALRP 930 GI+L++++T I+ +A NYR P P Q+ ++ CW+ +P RP Sbjct: 420 GILLYEIITYGKMPYSGMTGAQVIQMLA-QNYRLPQPSNCPQQFYNIMLECWNAEPKERP 478 Query: 931 SF 936 +F Sbjct: 479 TF 480
>O13146:EPHA3_DANRE Ephrin type-A receptor 3 precursor - Danio rerio (Zebrafish)| (Brachydanio rerio) Length = 981 Score = 105 bits (261), Expect = 8e-22 Identities = 85/315 (26%), Positives = 133/315 (42%), Gaps = 21/315 (6%) Frame = +1 Query: 226 GRFGKVFKGRCF-----GLEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGA 390 G FG+V GR ++VA+K K S Q F E +I + +HPN++R G Sbjct: 635 GEFGEVCSGRLRLPSKREIQVAIKSLKAG-YSEHQRRDFLSEASIMGQFDHPNIIRLEGV 693 Query: 391 CLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDLK 570 + +VTE ++ + + + R I GM Y+ N VH DL Sbjct: 694 VTRCKPVMIVTEYMENGSLDTFLKKHDGQFTVIQLLGMLRGIAAGMQYLSEMNYVHRDLA 753 Query: 571 PENVLLDFNGTAKIADFGLTVIRLDRQSLLH--GGPKGTPLWMAPEMLLGKPFDEKADIY 744 N+L++ N K++DFGL+ + D + G K W APE + + F +D++ Sbjct: 754 ARNILVNRNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAITYRKFTSASDVW 813 Query: 745 SFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPAL 924 S+GI++W++++ IKAV YR P P L L+ CW + Sbjct: 814 SYGIVMWEVISYGERPYWEMSNQDVIKAVD-EGYRLPAPMDCPVVLHQLMLDCWEKNRSD 872 Query: 925 RPSFTEIDNAYLQPIIVETAIPDEVGRVLWKNHFLNLDAVN----W----------EQFV 1062 RP F +I N + I +++ +W++ AVN W E F Sbjct: 873 RPKFGQIVNTLDRLIRNPSSLKQLANSAVWEDPVTPEAAVNTVEDWLDLIKMGQYKEHFS 932 Query: 1063 MAFYAILNLTLDVPS 1107 A Y L+ L V S Sbjct: 933 SAGYVTLDSVLYVSS 947
>P42681:TXK_HUMAN Tyrosine-protein kinase TXK - Homo sapiens (Human)| Length = 527 Score = 104 bits (260), Expect = 1e-21 Identities = 66/252 (26%), Positives = 115/252 (45%) Frame = +1 Query: 226 GRFGKVFKGRCFGLEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGACLKPL 405 G+FG V G + + V I + E S + E F +E + +++H +V+ G C++ Sbjct: 280 GQFGVVHLGE-WRSHIQVAIKAINEGSMSE-EDFIEEAKVMMKLSHSKLVQLYGVCIQRK 337 Query: 406 NFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDLKPENVL 585 +VTE L + + +DI +GM Y+ +H DL N L Sbjct: 338 PLYIVTEFMENGCLLNYLRENKGKLRKEMLLSVCQDICEGMEYLERNGYIHRDLAARNCL 397 Query: 586 LDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWMAPEMLLGKPFDEKADIYSFGIILW 765 + KI+DFG+T LD + + G K W PE+ L + K+D++SFG+++W Sbjct: 398 VSSTCIVKISDFGMTRYVLDDEYVSSFGAKFPIKWSPPEVFLFNKYSSKSDVWSFGVLMW 457 Query: 766 QLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPALRPSFTEI 945 ++ T ++A++ +R P + +++ CWH +P RP+F E+ Sbjct: 458 EVFTEGKMPFENKSNLQVVEAIS-EGFRLYRPHLAPMSIYEVMYSCWHEKPEGRPTFAEL 516 Query: 946 DNAYLQPIIVET 981 A + I ET Sbjct: 517 LRAVTE--IAET 526
>Q07E01:MET_ORNAN Hepatocyte growth factor receptor precursor - Ornithorhynchus| anatinus (Duckbill platypus) Length = 1382 Score = 104 bits (260), Expect = 1e-21 Identities = 73/250 (29%), Positives = 115/250 (46%), Gaps = 10/250 (4%) Frame = +1 Query: 226 GRFGKVFKGRCFG-----LEVAVK-IPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLG 387 G FG V+ G + AVK + ++ ++ E++ +F E I + +HPNV+ LG Sbjct: 1088 GHFGCVYHGTLLDNDDKKIHCAVKSLNRITDI--EEVSQFLTEGIIMKDFSHPNVLSLLG 1145 Query: 388 ACLKPLNFRLVT-EXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLD 564 CL+ LV N++ ++ + + KGM Y+ + VH D Sbjct: 1146 ICLRREGSPLVVLPYMKHGDLRNFIRNESHNPTVKDLIGFGLQVAKGMKYLASKKFVHRD 1205 Query: 565 LKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPL---WMAPEMLLGKPFDEKA 735 L N +LD T K+ADFGL D++ G L WMA E L + F K+ Sbjct: 1206 LAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTSKS 1265 Query: 736 DIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQ 915 D++SFG++LW+L+TR I + R P+ L ++ +CWHP Sbjct: 1266 DVWSFGVLLWELMTR-GAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLFEVMLKCWHPN 1324 Query: 916 PALRPSFTEI 945 +RPSF+E+ Sbjct: 1325 AEMRPSFSEL 1334
>A1X150:MET_ECHTE Hepatocyte growth factor receptor precursor - Echinops telfairi| (Lesser hedgehog tenrec) Length = 1380 Score = 104 bits (260), Expect = 1e-21 Identities = 73/250 (29%), Positives = 114/250 (45%), Gaps = 10/250 (4%) Frame = +1 Query: 226 GRFGKVFKGRCFG-----LEVAVK-IPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLG 387 G FG V+ G + AVK + ++ ++ ++ +F E I + +HPNV+ LG Sbjct: 1086 GHFGCVYHGTLLDNDDRKIHCAVKSLNRITDIG--EVSQFLTEGIIMKDFSHPNVLSLLG 1143 Query: 388 ACLKPLNFRLVT-EXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLD 564 CL+ LV N+ ++ + + KGM Y+ + VH D Sbjct: 1144 ICLRSEGSPLVVLPYMKHGDLRNFIRNETHSPTVKDLIGFGLQVAKGMKYLASKKFVHRD 1203 Query: 565 LKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPL---WMAPEMLLGKPFDEKA 735 L N +LD T K+ADFGL D++ G L WMA E L + F K+ Sbjct: 1204 LAARNCMLDGKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKS 1263 Query: 736 DIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQ 915 D++SFG++LW+L+TR I + R P+ L ++ +CWHP+ Sbjct: 1264 DVWSFGVLLWELMTR-GAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPK 1322 Query: 916 PALRPSFTEI 945 +RPSFTE+ Sbjct: 1323 AEMRPSFTEL 1332
>Q8IR79:LIMK1_DROME LIM domain kinase 1 - Drosophila melanogaster (Fruit fly)| Length = 1257 Score = 104 bits (260), Expect = 1e-21 Identities = 73/238 (30%), Positives = 112/238 (47%), Gaps = 34/238 (14%) Frame = +1 Query: 169 AEQLIIEEELSKDKDGEDIGRFGKVFKGRCFGLEVAVKIPKVQELSPEQLEKFKQEVAIN 348 A L+I E+L + G FGKVFK + + ++ E F +EVA+ Sbjct: 398 ATDLVIGEKLGE-------GFFGKVFKVTHRQSGEVMVLKELHRADEEAQRNFIKEVAVL 450 Query: 349 SEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGM 528 ++H +V++F+G K +VTE + A+ L +R+R+ARDI GM Sbjct: 451 RLLDHRHVLKFIGVLYKDKKLHMVTEYVAGGCLKELIHDPAQVLPWPQRVRLARDIACGM 510 Query: 529 IYIHAANLVHLDLKPENVLLDFNGTAKIADFGLT----VIRLDRQSLLHGG--------- 669 Y+H+ N++H DL N L+ + + +ADFGL RL ++ GG Sbjct: 511 SYLHSMNIIHRDLNSMNCLVREDRSVIVADFGLARSVDAPRLPSGNMTPGGYGSGANSDA 570 Query: 670 ---PKGT------------------PLWMAPEMLLGKPFDEKADIYSFGIILWQLLTR 780 P GT P WMAPEM+ G +DEK D++SFGI+L +++ R Sbjct: 571 PMSPSGTLRRSKSRQRRQRYTVVGNPYWMAPEMMKGLKYDEKVDVFSFGIMLCEIIGR 628
>P29322:EPHA8_HUMAN Ephrin type-A receptor 8 precursor - Homo sapiens (Human)| Length = 1005 Score = 104 bits (260), Expect = 1e-21 Identities = 73/264 (27%), Positives = 117/264 (44%), Gaps = 2/264 (0%) Frame = +1 Query: 160 EIPAEQLIIEEELSKDKDGEDIGRFGKVFKGRCFGLEVAVKIPKVQELSPEQLEKFKQEV 339 EI A ++ IE+ + GE +G++ + VA+K K + Q F E Sbjct: 629 EIEASRIHIEKIIGSGDSGEVC--YGRLRVPGQRDVPVAIKALKAG-YTERQRRDFLSEA 685 Query: 340 AINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIV 519 +I + +HPN++R G + +VTE ++ + + + R + Sbjct: 686 SIMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDTFLRTHDGQFTIMQLVGMLRGVG 745 Query: 520 KGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLH--GGPKGTPLWM 693 GM Y+ VH DL NVL+D N K++DFGL+ + D + G K W Sbjct: 746 AGMRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGLSRVLEDDPDAAYTTTGGKIPIRWT 805 Query: 694 APEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTN 873 APE + + F +D++SFG+++W++L I +V YR P P G Sbjct: 806 APEAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNRDVISSVE-EGYRLPAPMGCP 864 Query: 874 QKLSYLIHRCWHPQPALRPSFTEI 945 L L+ CWH A RP F++I Sbjct: 865 HALHQLMLDCWHKDRAQRPRFSQI 888
>Q62838:MUSK_RAT Muscle, skeletal receptor tyrosine protein kinase precursor - Rattus| norvegicus (Rat) Length = 868 Score = 104 bits (259), Expect = 1e-21 Identities = 80/271 (29%), Positives = 120/271 (44%), Gaps = 31/271 (11%) Frame = +1 Query: 226 GRFGKVFKGRCFGL-------EVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFL 384 G FG+VF+ R GL VAVK+ K +E S + F++E A+ +E ++PN+V+ L Sbjct: 583 GAFGRVFQARAPGLLPYEPFTMVAVKMLK-EEASADMQADFQREAALMAEFDNPNIVKLL 641 Query: 385 GACL--KPLNF--------------RLVTEXXXXXXXXXXXSNKAR-------PLSLARR 495 G C KP+ R ++ S +AR PLS A + Sbjct: 642 GVCAVGKPMCLLFEYMAYGDLNEFLRSMSPHTVCSLSHSDLSTRARVSSPGPPPLSCAEQ 701 Query: 496 MRIARDIVKGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPK 675 + IAR + GM Y+ VH DL N L+ N KIADFGL+ G Sbjct: 702 LCIARQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYSADYYKADGND 761 Query: 676 GTPL-WMAPEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRP 852 P+ WM PE + + ++D++++G++LW++ + I V N Sbjct: 762 AIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNIL- 820 Query: 853 PMPQGTNQKLSYLIHRCWHPQPALRPSFTEI 945 P+ +L L+ CW PA RPSF I Sbjct: 821 ACPENCPLELYNLMRLCWSKLPADRPSFCSI 851
>Q66HA1:M3K11_RAT Mitogen-activated protein kinase kinase kinase 11 - Rattus| norvegicus (Rat) Length = 850 Score = 104 bits (259), Expect = 1e-21 Identities = 79/254 (31%), Positives = 112/254 (44%), Gaps = 13/254 (5%) Frame = +1 Query: 223 IGRFGKVFKGRCFGLEVAVKIPKVQ--ELSPEQLEKFKQEVAINSEINHPNVVRFLGACL 396 IG FGKV++G G VAVK + E E +QE + + + HPN++ CL Sbjct: 126 IGGFGKVYRGSWRGELVAVKAARQDPDEDISVTAESVRQEARLFAMLAHPNIIALKAVCL 185 Query: 397 KPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLV---HLDL 567 + N LV E + + P + + A I +GM Y+H LV H DL Sbjct: 186 EEPNLCLVMEYAAGGPLSRALAGRRVPPHVL--VNWAVQIARGMHYLHCEALVPVIHRDL 243 Query: 568 KPENVLL-------DF-NGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWMAPEMLLGKPF 723 K N+LL D + T KI DFGL + GT WMAPE++ F Sbjct: 244 KSNNILLLQPIEGDDMEHKTLKITDFGLA---REWHKTTQMSAAGTYAWMAPEVIKASTF 300 Query: 724 DEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRC 903 + +D++SFG++LW+LLT VA+N P+P + + L+ C Sbjct: 301 SKGSDVWSFGVLLWELLT-GEVPYRGIDCLAVAYGVAVNKLTLPIPSTCPEPFAQLMADC 359 Query: 904 WHPQPALRPSFTEI 945 W P RP F I Sbjct: 360 WAQDPHRRPDFASI 373
>Q80XI6:M3K11_MOUSE Mitogen-activated protein kinase kinase kinase 11 - Mus musculus| (Mouse) Length = 850 Score = 104 bits (259), Expect = 1e-21 Identities = 79/254 (31%), Positives = 112/254 (44%), Gaps = 13/254 (5%) Frame = +1 Query: 223 IGRFGKVFKGRCFGLEVAVKIPKVQ--ELSPEQLEKFKQEVAINSEINHPNVVRFLGACL 396 IG FGKV++G G VAVK + E E +QE + + + HPN++ CL Sbjct: 126 IGGFGKVYRGSWRGELVAVKAARQDPDEDISVTAESVRQEARLFAMLAHPNIIALKAVCL 185 Query: 397 KPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLV---HLDL 567 + N LV E + + P + + A I +GM Y+H LV H DL Sbjct: 186 EEPNLCLVMEYAAGGPLSRALAGRRVPPHVL--VNWAVQIARGMHYLHCEALVPVIHRDL 243 Query: 568 KPENVLL-------DF-NGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWMAPEMLLGKPF 723 K N+LL D + T KI DFGL + GT WMAPE++ F Sbjct: 244 KSNNILLLQPIEGDDMEHKTLKITDFGLA---REWHKTTQMSAAGTYAWMAPEVIKASTF 300 Query: 724 DEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRC 903 + +D++SFG++LW+LLT VA+N P+P + + L+ C Sbjct: 301 SKGSDVWSFGVLLWELLT-GEVPYRGIDCLAVAYGVAVNKLTLPIPSTCPEPFAQLMADC 359 Query: 904 WHPQPALRPSFTEI 945 W P RP F I Sbjct: 360 WAQDPHRRPDFASI 373
>Q16584:M3K11_HUMAN Mitogen-activated protein kinase kinase kinase 11 - Homo sapiens| (Human) Length = 847 Score = 104 bits (259), Expect = 1e-21 Identities = 79/254 (31%), Positives = 112/254 (44%), Gaps = 13/254 (5%) Frame = +1 Query: 223 IGRFGKVFKGRCFGLEVAVKIPKVQ--ELSPEQLEKFKQEVAINSEINHPNVVRFLGACL 396 IG FGKV++G G VAVK + E E +QE + + + HPN++ CL Sbjct: 125 IGGFGKVYRGSWRGELVAVKAARQDPDEDISVTAESVRQEARLFAMLAHPNIIALKAVCL 184 Query: 397 KPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLV---HLDL 567 + N LV E + + P + + A I +GM Y+H LV H DL Sbjct: 185 EEPNLCLVMEYAAGGPLSRALAGRRVPPHVL--VNWAVQIARGMHYLHCEALVPVIHRDL 242 Query: 568 KPENVLL-------DF-NGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWMAPEMLLGKPF 723 K N+LL D + T KI DFGL + GT WMAPE++ F Sbjct: 243 KSNNILLLQPIESDDMEHKTLKITDFGLA---REWHKTTQMSAAGTYAWMAPEVIKASTF 299 Query: 724 DEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRC 903 + +D++SFG++LW+LLT VA+N P+P + + L+ C Sbjct: 300 SKGSDVWSFGVLLWELLT-GEVPYRGIDCLAVAYGVAVNKLTLPIPSTCPEPFAQLMADC 358 Query: 904 WHPQPALRPSFTEI 945 W P RP F I Sbjct: 359 WAQDPHRRPDFASI 372
>Q05876:FYN_CHICK Proto-oncogene tyrosine-protein kinase Fyn - Gallus gallus (Chicken)| Length = 534 Score = 104 bits (259), Expect = 1e-21 Identities = 79/261 (30%), Positives = 120/261 (45%), Gaps = 2/261 (0%) Frame = +1 Query: 160 EIPAEQLIIEEELSKDKDGEDIGRFGKVFKGRCFG-LEVAVKIPKVQELSPEQLEKFKQE 336 E+ + L +E++L + G F +V++G G +VA+K K +SPE F +E Sbjct: 262 EVARDSLFLEQKLGQ-------GCFAEVWRGTWNGNTKVAIKTLKPGTMSPES---FLEE 311 Query: 337 VAINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSN-KARPLSLARRMRIARD 513 I ++ H +V+ L A + +VTE + + R L L + +A Sbjct: 312 AQIMKKLKHDKLVQ-LYAVVSRRPIYIVTEYMSKGSLLIFLKDGEGRALKLPNLVDMAAQ 370 Query: 514 IVKGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWM 693 + GM YI N +H DL+ N+L+ KIADFGL + D + G K W Sbjct: 371 VAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWT 430 Query: 694 APEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTN 873 APE L F K+D++SFGI+L +L+T+ ++ V YR P PQ Sbjct: 431 APEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVE-RGYRMPCPQDCP 489 Query: 874 QKLSYLIHRCWHPQPALRPSF 936 L L+ CW P RP+F Sbjct: 490 ISLHELMIHCWKKDPEERPTF 510
>Q8MY86:FGFR1_DUGJA Fibroblast growth factor receptor 1 precursor - Dugesia japonica| (Planarian) Length = 854 Score = 104 bits (259), Expect = 1e-21 Identities = 82/286 (28%), Positives = 134/286 (46%), Gaps = 24/286 (8%) Frame = +1 Query: 160 EIPAEQLIIEEELSKDKDGEDIGRFGKVFKG-------RCFGLEVAVKIPKVQELSPEQL 318 E P E+L +++ K GE G FG V++G R ++VAVK+ + + S + Sbjct: 544 EFPREKL----KITNKKLGE--GAFGMVYEGIANDIGNRSNPIKVAVKMMR-DDFSDSNV 596 Query: 319 EKFKQEVAINSEIN-HPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARR 495 F +E+ I I HPNV++ LG C + R++ E K + S +++ Sbjct: 597 HDFVKEMEIMKHIGRHPNVIQLLGLCTQKGPLRVIVELAPYGNLRDFVRAKNKKYSKSKK 656 Query: 496 M----------RIARDIVKGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLTVI--- 636 + + I +GM Y+ + ++VH DL N+L+ + KIADFGLT I Sbjct: 657 IIGNFTSSILCTYSLQIARGMTYLASRSVVHRDLSARNILVGEHFEMKIADFGLTRIVDY 716 Query: 637 --RLDRQSLLHGGPKGTPL-WMAPEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXX 807 R +L P+ WMAPE LL K + K+D++S+GI+LW++ T Sbjct: 717 YYRKKTDGIL-------PVKWMAPEALLEKKYTTKSDVWSYGILLWEIFTLGDSPYSAIL 769 Query: 808 XXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPALRPSFTEI 945 + + ++ P P+ N ++ L+ CW RP+F EI Sbjct: 770 PEKVVDLIR-KGFQNPKPELANFEIYRLMQHCWSLSSENRPNFFEI 814
>Q07494:EPHB1_CHICK Ephrin type-B receptor 1 - Gallus gallus (Chicken)| Length = 984 Score = 104 bits (259), Expect = 1e-21 Identities = 76/275 (27%), Positives = 119/275 (43%), Gaps = 18/275 (6%) Frame = +1 Query: 226 GRFGKVFKGRCF-----GLEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGA 390 G FG+V+KGR + VA+K K S +Q F E +I + +HPN++R G Sbjct: 628 GEFGEVYKGRLKLPGKREIYVAIKTLKAG-YSEKQRRDFLSEASIMGQFDHPNIIRLEGV 686 Query: 391 CLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDLK 570 K ++TE ++ + + + R I GM Y+ N VH DL Sbjct: 687 VTKSRPVMIITEFMENGALDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLAEMNYVHRDLA 746 Query: 571 PENVLLDFNGTAKIADFGLTVIRLDRQS----LLHGGPKGTPLWMAPEMLLGKPFDEKAD 738 N+L++ N K++DFGL+ D S G K W APE + + F +D Sbjct: 747 ARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVRWTAPEAIAYRKFTSASD 806 Query: 739 IYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQP 918 ++S+GI++W++++ I A+ +YR P P L L+ CW Sbjct: 807 VWSYGIVMWEVMSFGERPYWDMSNQDVINAIE-QDYRLPPPMDCPAALHQLMLDCWQKDR 865 Query: 919 ALRPSFTEIDN---------AYLQPIIVETAIPDE 996 RP EI N A L+ + TA+P + Sbjct: 866 NTRPRLAEIVNTLDKMIRNPASLKTVATITAVPSQ 900
>Q1KL86:EPHA2_MACFA Ephrin type-A receptor 2 precursor - Macaca fascicularis (Crab eating| macaque) (Cynomolgus monkey) Length = 976 Score = 104 bits (259), Expect = 1e-21 Identities = 68/248 (27%), Positives = 114/248 (45%), Gaps = 8/248 (3%) Frame = +1 Query: 226 GRFGKVFKGRCFG------LEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLG 387 G FG+V+KG + VA+K K ++++ F E I + +H N++R G Sbjct: 622 GEFGEVYKGTLKTSSGKKEVPVAIKTLKAGYTEKQRVD-FLGEAGIMGQFSHHNIIRLEG 680 Query: 388 ACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDL 567 K ++TE K S+ + + + R I GM Y+ N VH DL Sbjct: 681 VISKYKPMMIITEFMENGALDKFLREKDGEFSVLQLVGMLRGIAAGMKYLANMNYVHRDL 740 Query: 568 KPENVLLDFNGTAKIADFGLTVIRLDRQSLLH--GGPKGTPLWMAPEMLLGKPFDEKADI 741 N+L++ N K++DFGL+ + D + G K W APE + + F +D+ Sbjct: 741 AARNILVNSNLVCKVSDFGLSRVLEDDPEATYTTSGGKIPIRWTAPEAISYRKFTSASDV 800 Query: 742 YSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPA 921 +SFGI++W+++T +KA+ + +R P P + L+ +CW + A Sbjct: 801 WSFGIVMWEVMTYGERPYWELSNHEVMKAIN-DGFRLPTPMDCPSAIYQLMMQCWQQERA 859 Query: 922 LRPSFTEI 945 RP F +I Sbjct: 860 RRPKFADI 867
>P29317:EPHA2_HUMAN Ephrin type-A receptor 2 precursor - Homo sapiens (Human)| Length = 976 Score = 104 bits (259), Expect = 1e-21 Identities = 68/248 (27%), Positives = 114/248 (45%), Gaps = 8/248 (3%) Frame = +1 Query: 226 GRFGKVFKGRCFG------LEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLG 387 G FG+V+KG + VA+K K ++++ F E I + +H N++R G Sbjct: 622 GEFGEVYKGMLKTSSGKKEVPVAIKTLKAGYTEKQRVD-FLGEAGIMGQFSHHNIIRLEG 680 Query: 388 ACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDL 567 K ++TE K S+ + + + R I GM Y+ N VH DL Sbjct: 681 VISKYKPMMIITEYMENGALDKFLREKDGEFSVLQLVGMLRGIAAGMKYLANMNYVHRDL 740 Query: 568 KPENVLLDFNGTAKIADFGLTVIRLDRQSLLH--GGPKGTPLWMAPEMLLGKPFDEKADI 741 N+L++ N K++DFGL+ + D + G K W APE + + F +D+ Sbjct: 741 AARNILVNSNLVCKVSDFGLSRVLEDDPEATYTTSGGKIPIRWTAPEAISYRKFTSASDV 800 Query: 742 YSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPA 921 +SFGI++W+++T +KA+ + +R P P + L+ +CW + A Sbjct: 801 WSFGIVMWEVMTYGERPYWELSNHEVMKAIN-DGFRLPTPMDCPSAIYQLMMQCWQQERA 859 Query: 922 LRPSFTEI 945 RP F +I Sbjct: 860 RRPKFADI 867
>Q91736:EPB1B_XENLA Ephrin type-B receptor 1-B - Xenopus laevis (African clawed frog)| Length = 902 Score = 104 bits (259), Expect = 1e-21 Identities = 72/251 (28%), Positives = 111/251 (44%), Gaps = 9/251 (3%) Frame = +1 Query: 226 GRFGKVFKGRCF-----GLEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGA 390 G FG+V+KGR + VA+K K S +Q F E +I + +HPN++R G Sbjct: 546 GEFGEVYKGRLKLPSKREISVAIKTLKAG-YSEKQRRDFLSEASIMGQFDHPNIIRLEGV 604 Query: 391 CLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDLK 570 K ++TE ++ + + + R I GM Y+ N VH DL Sbjct: 605 VTKSRPVMIITEFMENGALDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLA 664 Query: 571 PENVLLDFNGTAKIADFGLTVIRLDRQS----LLHGGPKGTPLWMAPEMLLGKPFDEKAD 738 N+L++ N K++DFGL+ D S G K W APE + + F +D Sbjct: 665 ARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVRWTAPEAIRYRKFTSASD 724 Query: 739 IYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQP 918 ++S+GI++W++++ I A+ +YR P P L L+ CW Sbjct: 725 VWSYGIVMWEVMSYGERPYWDMSNQDVINAIE-QDYRLPPPMDCPAALHQLMLDCWQKDR 783 Query: 919 ALRPSFTEIDN 951 RP F EI N Sbjct: 784 NSRPRFGEIVN 794
>Q07E48:MET_DASNO Hepatocyte growth factor receptor precursor - Dasypus novemcinctus| (Nine-banded armadillo) Length = 1381 Score = 103 bits (258), Expect = 2e-21 Identities = 72/250 (28%), Positives = 115/250 (46%), Gaps = 10/250 (4%) Frame = +1 Query: 226 GRFGKVFKGRCFG-----LEVAVK-IPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLG 387 G FG V+ G + AVK + ++ ++ ++ +F E I + +HPNV+ LG Sbjct: 1088 GHFGCVYHGTLLDSDDKKIHCAVKSLNRITDIG--EVSQFLTEGIIMKDFSHPNVLSLLG 1145 Query: 388 ACLKPLNFRLVT-EXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLD 564 CL+ LV N+ ++ + + KGM Y+ + VH D Sbjct: 1146 ICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRD 1205 Query: 565 LKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPL---WMAPEMLLGKPFDEKA 735 L N +LD T K+ADFGL D++ G L WMA E L + F K+ Sbjct: 1206 LAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKS 1265 Query: 736 DIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQ 915 D++SFG++LW+L+TR I + R P+ +L ++ +CWHP+ Sbjct: 1266 DVWSFGVLLWELMTR-GAPPYPDVNTFDITVYLLQGRRLLQPEYCPDRLYEVMLKCWHPK 1324 Query: 916 PALRPSFTEI 945 +RPSF+E+ Sbjct: 1325 AEMRPSFSEL 1334
>P42688:SRK2_SPOLA Tyrosine-protein kinase SRK2 - Spongilla lacustris (Freshwater| sponge) Length = 362 Score = 103 bits (257), Expect = 2e-21 Identities = 68/238 (28%), Positives = 107/238 (44%), Gaps = 1/238 (0%) Frame = +1 Query: 226 GRFGKVFKGRCFG-LEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGACLKP 402 G+FG+V++G VAVK K + P F E I ++ HP +++ C + Sbjct: 104 GQFGEVYQGLWNNSTPVAVKTLKAGTMQPAA---FLAEAQIMKKLRHPKLIQLYAVCTQG 160 Query: 403 LNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDLKPENV 582 ++TE +A L L + + +A + GM Y+ N +H DL N+ Sbjct: 161 EPVYIITELMSKGSLLDYLQGEAGALKLPQLIDMAAQVAAGMAYLELHNYIHRDLAARNI 220 Query: 583 LLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWMAPEMLLGKPFDEKADIYSFGIIL 762 L+ N K+ADFGL + + G K W APE L F K+D++SFGI++ Sbjct: 221 LVGDNNICKVADFGLARLIVSDDYNATEGAKFPIKWTAPEAALFNRFSIKSDVWSFGILI 280 Query: 763 WQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPALRPSF 936 +L+T ++ + YR P P T + L ++ CW PA RP+F Sbjct: 281 TELVTYGRIPYPGMSNAEVLQNLD-KGYRMPCPVTTPESLYQIMLDCWKRNPADRPTF 337
>Q07E37:MET_NEONE Hepatocyte growth factor receptor precursor - Neofelis nebulosa| (Clouded leopard) Length = 1382 Score = 103 bits (257), Expect = 2e-21 Identities = 73/250 (29%), Positives = 114/250 (45%), Gaps = 10/250 (4%) Frame = +1 Query: 226 GRFGKVFKGRCFG-----LEVAVK-IPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLG 387 G FG V+ G + AVK + ++ ++ ++ +F E I + +HPNV+ LG Sbjct: 1088 GHFGCVYHGTLLDSDDKKIHCAVKSLNRITDIG--EVSQFLTEGIIMKDFSHPNVLSLLG 1145 Query: 388 ACLKPLNFRLVT-EXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLD 564 CL+ LV N+ ++ + + KGM Y+ + VH D Sbjct: 1146 ICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRD 1205 Query: 565 LKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPL---WMAPEMLLGKPFDEKA 735 L N +LD T K+ADFGL D++ G L WMA E L + F K+ Sbjct: 1206 LAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKS 1265 Query: 736 DIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQ 915 D++SFG++LW+L+TR I + R P+ L ++ +CWHP+ Sbjct: 1266 DVWSFGVLLWELMTR-GAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPK 1324 Query: 916 PALRPSFTEI 945 LRPSF+E+ Sbjct: 1325 AELRPSFSEL 1334
>Q07E24:MET_MUSPF Hepatocyte growth factor receptor precursor - Mustela putorius furo| (European domestic ferret) (Mustela furo) Length = 1382 Score = 103 bits (257), Expect = 2e-21 Identities = 73/250 (29%), Positives = 114/250 (45%), Gaps = 10/250 (4%) Frame = +1 Query: 226 GRFGKVFKGRCFG-----LEVAVK-IPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLG 387 G FG V+ G + AVK + ++ ++ ++ +F E I + +HPNV+ LG Sbjct: 1088 GHFGCVYHGTLLDNDDKKIHCAVKSLNRITDIG--EVSQFLTEGIIMKDFSHPNVLSLLG 1145 Query: 388 ACLKPLNFRLVT-EXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLD 564 CL+ LV N+ ++ + + KGM Y+ + VH D Sbjct: 1146 ICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRD 1205 Query: 565 LKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPL---WMAPEMLLGKPFDEKA 735 L N +LD T K+ADFGL D++ G L WMA E L + F K+ Sbjct: 1206 LAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKS 1265 Query: 736 DIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQ 915 D++SFG++LW+L+TR I + R P+ L ++ +CWHP+ Sbjct: 1266 DVWSFGVLLWELMTR-GAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPK 1324 Query: 916 PALRPSFTEI 945 LRPSF+E+ Sbjct: 1325 AELRPSFSEL 1334
>P08581:MET_HUMAN Hepatocyte growth factor receptor precursor - Homo sapiens (Human)| Length = 1390 Score = 103 bits (257), Expect = 2e-21 Identities = 70/248 (28%), Positives = 112/248 (45%), Gaps = 8/248 (3%) Frame = +1 Query: 226 GRFGKVFKGRCF---GLEVAVKIPKVQELSP-EQLEKFKQEVAINSEINHPNVVRFLGAC 393 G FG V+ G G ++ + + ++ ++ +F E I + +HPNV+ LG C Sbjct: 1087 GHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGIC 1146 Query: 394 LKPLNFRLVT-EXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDLK 570 L+ LV N+ ++ + + KGM Y+ + VH DL Sbjct: 1147 LRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLA 1206 Query: 571 PENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPL---WMAPEMLLGKPFDEKADI 741 N +LD T K+ADFGL D++ G L WMA E L + F K+D+ Sbjct: 1207 ARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDV 1266 Query: 742 YSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPA 921 +SFG++LW+L+TR I + R P+ L ++ +CWHP+ Sbjct: 1267 WSFGVVLWELMTR-GAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAE 1325 Query: 922 LRPSFTEI 945 +RPSF+E+ Sbjct: 1326 MRPSFSEL 1333
>Q2QLA9:MET_HORSE Hepatocyte growth factor receptor precursor - Equus caballus (Horse)| Length = 1381 Score = 103 bits (257), Expect = 2e-21 Identities = 73/250 (29%), Positives = 114/250 (45%), Gaps = 10/250 (4%) Frame = +1 Query: 226 GRFGKVFKGRCFG-----LEVAVK-IPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLG 387 G FG V+ G + AVK + ++ ++ ++ +F E I + +HPNV+ LG Sbjct: 1087 GHFGCVYHGTLLDNDDKKIHCAVKSLNRITDIG--EVSQFLTEGIIMKDFSHPNVLSLLG 1144 Query: 388 ACLKPLNFRLVT-EXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLD 564 CL+ LV N+ ++ + + KGM Y+ + VH D Sbjct: 1145 ICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRD 1204 Query: 565 LKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPL---WMAPEMLLGKPFDEKA 735 L N +LD T K+ADFGL D++ G L WMA E L + F K+ Sbjct: 1205 LAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKS 1264 Query: 736 DIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQ 915 D++SFG++LW+L+TR I + R P+ L ++ +CWHP+ Sbjct: 1265 DVWSFGVLLWELMTR-GAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPK 1323 Query: 916 PALRPSFTEI 945 LRPSF+E+ Sbjct: 1324 AELRPSFSEL 1333
>A0M8S8:MET_FELCA Hepatocyte growth factor receptor precursor - Felis silvestris catus| (Cat) Length = 1382 Score = 103 bits (257), Expect = 2e-21 Identities = 73/250 (29%), Positives = 114/250 (45%), Gaps = 10/250 (4%) Frame = +1 Query: 226 GRFGKVFKGRCFG-----LEVAVK-IPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLG 387 G FG V+ G + AVK + ++ ++ ++ +F E I + +HPNV+ LG Sbjct: 1088 GHFGCVYHGTLLDSDDKKIHCAVKSLNRITDIG--EVSQFLTEGIIMKDFSHPNVLSLLG 1145 Query: 388 ACLKPLNFRLVT-EXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLD 564 CL+ LV N+ ++ + + KGM Y+ + VH D Sbjct: 1146 ICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRD 1205 Query: 565 LKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPL---WMAPEMLLGKPFDEKA 735 L N +LD T K+ADFGL D++ G L WMA E L + F K+ Sbjct: 1206 LAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKS 1265 Query: 736 DIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQ 915 D++SFG++LW+L+TR I + R P+ L ++ +CWHP+ Sbjct: 1266 DVWSFGVLLWELMTR-GAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPK 1324 Query: 916 PALRPSFTEI 945 LRPSF+E+ Sbjct: 1325 AELRPSFSEL 1334
>Q75ZY9:MET_CANFA Hepatocyte growth factor receptor precursor - Canis familiaris (Dog)| Length = 1382 Score = 103 bits (257), Expect = 2e-21 Identities = 73/250 (29%), Positives = 114/250 (45%), Gaps = 10/250 (4%) Frame = +1 Query: 226 GRFGKVFKGRCFG-----LEVAVK-IPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLG 387 G FG V+ G + AVK + ++ ++ ++ +F E I + +HPNV+ LG Sbjct: 1088 GHFGCVYHGTLLDNDDKKIHCAVKSLNRITDIG--EVSQFLTEGIIMKDFSHPNVLSLLG 1145 Query: 388 ACLKPLNFRLVT-EXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLD 564 CL+ LV N+ ++ + + KGM Y+ + VH D Sbjct: 1146 ICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRD 1205 Query: 565 LKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPL---WMAPEMLLGKPFDEKA 735 L N +LD T K+ADFGL D++ G L WMA E L + F K+ Sbjct: 1206 LAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKS 1265 Query: 736 DIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQ 915 D++SFG++LW+L+TR I + R P+ L ++ +CWHP+ Sbjct: 1266 DVWSFGVLLWELMTR-GAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPR 1324 Query: 916 PALRPSFTEI 945 LRPSF+E+ Sbjct: 1325 AELRPSFSEL 1334
>Q5TCX8:M3KL4_HUMAN Mitogen-activated protein kinase kinase kinase - Homo sapiens| (Human) Length = 1036 Score = 102 bits (255), Expect(2) = 3e-21 Identities = 82/269 (30%), Positives = 116/269 (43%), Gaps = 29/269 (10%) Frame = +1 Query: 226 GRFGKVFKGRCFGLEVAVKIPKVQELSPEQ-----LEKFKQEVAINSEINHPNVVRFLGA 390 G FG+V++ G EVAVK + PEQ E ++E + + + HPN++ G Sbjct: 133 GGFGQVYRATWQGQEVAVKAARQD---PEQDAAAAAESVRREARLFAMLRHPNIIELRGV 189 Query: 391 CLKPLNFRLVTEXXXXXXXXXXXSN-KARPLSLARRMRIAR------------DIVKGMI 531 CL+ + LV E + A P A R AR I +GM+ Sbjct: 190 CLQQPHLCLVLEFARGGALNRALAAANAAPDPRAPGPRRARRIPPHVLVNWAVQIARGML 249 Query: 532 YIHAANLV---HLDLKPENVLL--------DFNGTAKIADFGLTVIRLDRQSLLHGGPKG 678 Y+H V H DLK N+LL N T KI DFGL + G Sbjct: 250 YLHEEAFVPILHRDLKSSNILLLEKIEHDDICNKTLKITDFGLA---REWHRTTKMSTAG 306 Query: 679 TPLWMAPEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPM 858 T WMAPE++ F + +DI+S+G++LW+LLT VA+N P+ Sbjct: 307 TYAWMAPEVIKSSLFSKGSDIWSYGVLLWELLT-GEVPYRGIDGLAVAYGVAVNKLTLPI 365 Query: 859 PQGTNQKLSYLIHRCWHPQPALRPSFTEI 945 P + + L+ CW P +RPSF I Sbjct: 366 PSTCPEPFAKLMKECWQQDPHIRPSFALI 394 Score = 21.2 bits (43), Expect(2) = 3e-21 Identities = 9/20 (45%), Positives = 11/20 (55%) Frame = +2 Query: 53 CPPSATGAPPCSHLQGPAPV 112 C P+A+ APP S P V Sbjct: 100 CRPAASPAPPPSRPSSPVHV 119
>Q09YH7:MET_SAIBB Hepatocyte growth factor receptor precursor - Saimiri boliviensis| boliviensis (Bolivian squirrel monkey) Length = 1381 Score = 103 bits (256), Expect = 3e-21 Identities = 70/248 (28%), Positives = 112/248 (45%), Gaps = 8/248 (3%) Frame = +1 Query: 226 GRFGKVFKGRCF---GLEVAVKIPKVQELSP-EQLEKFKQEVAINSEINHPNVVRFLGAC 393 G FG V+ G G ++ + + ++ ++ +F E I + +HPNV+ LG C Sbjct: 1087 GHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGIC 1146 Query: 394 LKPLNFRLVT-EXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDLK 570 L+ LV N+ ++ + + KGM Y+ + VH DL Sbjct: 1147 LRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLA 1206 Query: 571 PENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPL---WMAPEMLLGKPFDEKADI 741 N +LD T K+ADFGL D++ G L WMA E L + F K+D+ Sbjct: 1207 ARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDV 1266 Query: 742 YSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPA 921 +SFG++LW+L+TR I + R P+ L ++ +CWHP+ Sbjct: 1267 WSFGVLLWELMTR-GAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAE 1325 Query: 922 LRPSFTEI 945 +RPSF+E+ Sbjct: 1326 MRPSFSEL 1333
>Q09YN5:MET_RABIT Hepatocyte growth factor receptor precursor - Oryctolagus cuniculus| (Rabbit) Length = 1382 Score = 103 bits (256), Expect = 3e-21 Identities = 70/248 (28%), Positives = 112/248 (45%), Gaps = 8/248 (3%) Frame = +1 Query: 226 GRFGKVFKGRCF---GLEVAVKIPKVQELSP-EQLEKFKQEVAINSEINHPNVVRFLGAC 393 G FG V+ G G ++ + + ++ ++ +F E I + +HPNV+ LG C Sbjct: 1088 GHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGIC 1147 Query: 394 LKPLNFRLVT-EXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDLK 570 L+ LV N+ ++ + + KGM Y+ + VH DL Sbjct: 1148 LRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLA 1207 Query: 571 PENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPL---WMAPEMLLGKPFDEKADI 741 N +LD T K+ADFGL D++ G L WMA E L + F K+D+ Sbjct: 1208 ARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDV 1267 Query: 742 YSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPA 921 +SFG++LW+L+TR I + R P+ L ++ +CWHP+ Sbjct: 1268 WSFGVLLWELMTR-GAPPYPDVNTFDITVYLLQGRRLLQPEYCPDALYEVMLKCWHPKAE 1326 Query: 922 LRPSFTEI 945 +RPSF+E+ Sbjct: 1327 MRPSFSEL 1334
>Q2IBD8:MET_PONPY Hepatocyte growth factor receptor precursor - Pongo pygmaeus| (Orangutan) Length = 1390 Score = 103 bits (256), Expect = 3e-21 Identities = 70/248 (28%), Positives = 112/248 (45%), Gaps = 8/248 (3%) Frame = +1 Query: 226 GRFGKVFKGRCF---GLEVAVKIPKVQELSP-EQLEKFKQEVAINSEINHPNVVRFLGAC 393 G FG V+ G G ++ + + ++ ++ +F E I + +HPNV+ LG C Sbjct: 1087 GHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGIC 1146 Query: 394 LKPLNFRLVT-EXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDLK 570 L+ LV N+ ++ + + KGM Y+ + VH DL Sbjct: 1147 LRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLA 1206 Query: 571 PENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPL---WMAPEMLLGKPFDEKADI 741 N +LD T K+ADFGL D++ G L WMA E L + F K+D+ Sbjct: 1207 ARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDV 1266 Query: 742 YSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPA 921 +SFG++LW+L+TR I + R P+ L ++ +CWHP+ Sbjct: 1267 WSFGVLLWELMTR-GAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAE 1325 Query: 922 LRPSFTEI 945 +RPSF+E+ Sbjct: 1326 MRPSFSEL 1333
>A0M8R7:MET_PAPAN Hepatocyte growth factor receptor precursor - Papio anubis (Olive| baboon) Length = 1381 Score = 103 bits (256), Expect = 3e-21 Identities = 70/248 (28%), Positives = 112/248 (45%), Gaps = 8/248 (3%) Frame = +1 Query: 226 GRFGKVFKGRCF---GLEVAVKIPKVQELSP-EQLEKFKQEVAINSEINHPNVVRFLGAC 393 G FG V+ G G ++ + + ++ ++ +F E I + +HPNV+ LG C Sbjct: 1087 GHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGIC 1146 Query: 394 LKPLNFRLVT-EXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDLK 570 L+ LV N+ ++ + + KGM Y+ + VH DL Sbjct: 1147 LRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLA 1206 Query: 571 PENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPL---WMAPEMLLGKPFDEKADI 741 N +LD T K+ADFGL D++ G L WMA E L + F K+D+ Sbjct: 1207 ARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDV 1266 Query: 742 YSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPA 921 +SFG++LW+L+TR I + R P+ L ++ +CWHP+ Sbjct: 1267 WSFGVLLWELMTR-GAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAE 1325 Query: 922 LRPSFTEI 945 +RPSF+E+ Sbjct: 1326 MRPSFSEL 1333
>Q2QLF1:MET_PANTR Hepatocyte growth factor receptor precursor - Pan troglodytes| (Chimpanzee) Length = 1390 Score = 103 bits (256), Expect = 3e-21 Identities = 70/248 (28%), Positives = 112/248 (45%), Gaps = 8/248 (3%) Frame = +1 Query: 226 GRFGKVFKGRCF---GLEVAVKIPKVQELSP-EQLEKFKQEVAINSEINHPNVVRFLGAC 393 G FG V+ G G ++ + + ++ ++ +F E I + +HPNV+ LG C Sbjct: 1087 GHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGIC 1146 Query: 394 LKPLNFRLVT-EXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDLK 570 L+ LV N+ ++ + + KGM Y+ + VH DL Sbjct: 1147 LRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLA 1206 Query: 571 PENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPL---WMAPEMLLGKPFDEKADI 741 N +LD T K+ADFGL D++ G L WMA E L + F K+D+ Sbjct: 1207 ARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDV 1266 Query: 742 YSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPA 921 +SFG++LW+L+TR I + R P+ L ++ +CWHP+ Sbjct: 1267 WSFGVLLWELMTR-GAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAE 1325 Query: 922 LRPSFTEI 945 +RPSF+E+ Sbjct: 1326 MRPSFSEL 1333
>Q2QL89:MET_MICMU Hepatocyte growth factor receptor precursor - Microcebus murinus| (Lesser mouse lemur) Length = 1382 Score = 103 bits (256), Expect = 3e-21 Identities = 70/248 (28%), Positives = 112/248 (45%), Gaps = 8/248 (3%) Frame = +1 Query: 226 GRFGKVFKGRCF---GLEVAVKIPKVQELSP-EQLEKFKQEVAINSEINHPNVVRFLGAC 393 G FG V+ G G ++ + + ++ ++ +F E I + +HPNV+ LG C Sbjct: 1088 GHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGIC 1147 Query: 394 LKPLNFRLVT-EXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDLK 570 L+ LV N+ ++ + + KGM Y+ + VH DL Sbjct: 1148 LRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLA 1207 Query: 571 PENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPL---WMAPEMLLGKPFDEKADI 741 N +LD T K+ADFGL D++ G L WMA E L + F K+D+ Sbjct: 1208 ARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDV 1267 Query: 742 YSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPA 921 +SFG++LW+L+TR I + R P+ L ++ +CWHP+ Sbjct: 1268 WSFGVLLWELMTR-GAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAE 1326 Query: 922 LRPSFTEI 945 +RPSF+E+ Sbjct: 1327 MRPSFSEL 1334
>Q07DY1:MET_HYLLE Hepatocyte growth factor receptor precursor - Hylobates leucogenys| (White-cheeked gibbon) Length = 1390 Score = 103 bits (256), Expect = 3e-21 Identities = 70/248 (28%), Positives = 112/248 (45%), Gaps = 8/248 (3%) Frame = +1 Query: 226 GRFGKVFKGRCF---GLEVAVKIPKVQELSP-EQLEKFKQEVAINSEINHPNVVRFLGAC 393 G FG V+ G G ++ + + ++ ++ +F E I + +HPNV+ LG C Sbjct: 1087 GHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGIC 1146 Query: 394 LKPLNFRLVT-EXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDLK 570 L+ LV N+ ++ + + KGM Y+ + VH DL Sbjct: 1147 LRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLA 1206 Query: 571 PENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPL---WMAPEMLLGKPFDEKADI 741 N +LD T K+ADFGL D++ G L WMA E L + F K+D+ Sbjct: 1207 ARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDV 1266 Query: 742 YSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPA 921 +SFG++LW+L+TR I + R P+ L ++ +CWHP+ Sbjct: 1267 WSFGVLLWELMTR-GAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAE 1325 Query: 922 LRPSFTEI 945 +RPSF+E+ Sbjct: 1326 MRPSFSEL 1333
>Q2IBF2:MET_GORGO Hepatocyte growth factor receptor precursor - Gorilla gorilla gorilla| (Lowland gorilla) Length = 1390 Score = 103 bits (256), Expect = 3e-21 Identities = 70/248 (28%), Positives = 112/248 (45%), Gaps = 8/248 (3%) Frame = +1 Query: 226 GRFGKVFKGRCF---GLEVAVKIPKVQELSP-EQLEKFKQEVAINSEINHPNVVRFLGAC 393 G FG V+ G G ++ + + ++ ++ +F E I + +HPNV+ LG C Sbjct: 1087 GHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGIC 1146 Query: 394 LKPLNFRLVT-EXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDLK 570 L+ LV N+ ++ + + KGM Y+ + VH DL Sbjct: 1147 LRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLA 1206 Query: 571 PENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPL---WMAPEMLLGKPFDEKADI 741 N +LD T K+ADFGL D++ G L WMA E L + F K+D+ Sbjct: 1207 ARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDV 1266 Query: 742 YSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPA 921 +SFG++LW+L+TR I + R P+ L ++ +CWHP+ Sbjct: 1267 WSFGVLLWELMTR-GAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAE 1325 Query: 922 LRPSFTEI 945 +RPSF+E+ Sbjct: 1326 MRPSFSEL 1333
>Q2IBG7:MET_EULMM Hepatocyte growth factor receptor precursor - Eulemur macaco macaco| (Black lemur) Length = 1382 Score = 103 bits (256), Expect = 3e-21 Identities = 70/248 (28%), Positives = 112/248 (45%), Gaps = 8/248 (3%) Frame = +1 Query: 226 GRFGKVFKGRCF---GLEVAVKIPKVQELSP-EQLEKFKQEVAINSEINHPNVVRFLGAC 393 G FG V+ G G ++ + + ++ ++ +F E I + +HPNV+ LG C Sbjct: 1088 GHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGIC 1147 Query: 394 LKPLNFRLVT-EXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDLK 570 L+ LV N+ ++ + + KGM Y+ + VH DL Sbjct: 1148 LRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLA 1207 Query: 571 PENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPL---WMAPEMLLGKPFDEKADI 741 N +LD T K+ADFGL D++ G L WMA E L + F K+D+ Sbjct: 1208 ARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDV 1267 Query: 742 YSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPA 921 +SFG++LW+L+TR I + R P+ L ++ +CWHP+ Sbjct: 1268 WSFGVLLWELMTR-GAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAE 1326 Query: 922 LRPSFTEI 945 +RPSF+E+ Sbjct: 1327 MRPSFSEL 1334
>Q07DZ1:MET_COLGU Hepatocyte growth factor receptor precursor - Colobus guereza| (Black-and-white colobus monkey) Length = 1381 Score = 103 bits (256), Expect = 3e-21 Identities = 70/248 (28%), Positives = 112/248 (45%), Gaps = 8/248 (3%) Frame = +1 Query: 226 GRFGKVFKGRCF---GLEVAVKIPKVQELSP-EQLEKFKQEVAINSEINHPNVVRFLGAC 393 G FG V+ G G ++ + + ++ ++ +F E I + +HPNV+ LG C Sbjct: 1087 GHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGIC 1146 Query: 394 LKPLNFRLVT-EXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDLK 570 L+ LV N+ ++ + + KGM Y+ + VH DL Sbjct: 1147 LRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLA 1206 Query: 571 PENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPL---WMAPEMLLGKPFDEKADI 741 N +LD T K+ADFGL D++ G L WMA E L + F K+D+ Sbjct: 1207 ARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDV 1266 Query: 742 YSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPA 921 +SFG++LW+L+TR I + R P+ L ++ +CWHP+ Sbjct: 1267 WSFGVLLWELMTR-GAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAE 1325 Query: 922 LRPSFTEI 945 +RPSF+E+ Sbjct: 1326 MRPSFSEL 1333
>Q2IBA6:MET_CERAE Hepatocyte growth factor receptor precursor - Cercopithecus aethiops| (Green monkey) (Grivet) Length = 1381 Score = 103 bits (256), Expect = 3e-21 Identities = 70/248 (28%), Positives = 112/248 (45%), Gaps = 8/248 (3%) Frame = +1 Query: 226 GRFGKVFKGRCF---GLEVAVKIPKVQELSP-EQLEKFKQEVAINSEINHPNVVRFLGAC 393 G FG V+ G G ++ + + ++ ++ +F E I + +HPNV+ LG C Sbjct: 1087 GHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGIC 1146 Query: 394 LKPLNFRLVT-EXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDLK 570 L+ LV N+ ++ + + KGM Y+ + VH DL Sbjct: 1147 LRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLA 1206 Query: 571 PENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPL---WMAPEMLLGKPFDEKADI 741 N +LD T K+ADFGL D++ G L WMA E L + F K+D+ Sbjct: 1207 ARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDV 1266 Query: 742 YSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPA 921 +SFG++LW+L+TR I + R P+ L ++ +CWHP+ Sbjct: 1267 WSFGVLLWELMTR-GAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAE 1325 Query: 922 LRPSFTEI 945 +RPSF+E+ Sbjct: 1326 MRPSFSEL 1333
>Q2QLC0:MET_CALMO Hepatocyte growth factor receptor precursor - Callicebus moloch| (Dusky titi monkey) Length = 1381 Score = 103 bits (256), Expect = 3e-21 Identities = 70/248 (28%), Positives = 112/248 (45%), Gaps = 8/248 (3%) Frame = +1 Query: 226 GRFGKVFKGRCF---GLEVAVKIPKVQELSP-EQLEKFKQEVAINSEINHPNVVRFLGAC 393 G FG V+ G G ++ + + ++ ++ +F E I + +HPNV+ LG C Sbjct: 1087 GHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGIC 1146 Query: 394 LKPLNFRLVT-EXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDLK 570 L+ LV N+ ++ + + KGM Y+ + VH DL Sbjct: 1147 LRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLA 1206 Query: 571 PENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPL---WMAPEMLLGKPFDEKADI 741 N +LD T K+ADFGL D++ G L WMA E L + F K+D+ Sbjct: 1207 ARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDV 1266 Query: 742 YSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPA 921 +SFG++LW+L+TR I + R P+ L ++ +CWHP+ Sbjct: 1267 WSFGVLLWELMTR-GAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAE 1325 Query: 922 LRPSFTEI 945 +RPSF+E+ Sbjct: 1326 MRPSFSEL 1333
>Q2QLG5:MET_CALJA Hepatocyte growth factor receptor precursor - Callithrix jacchus| (Common marmoset) Length = 1381 Score = 103 bits (256), Expect = 3e-21 Identities = 70/248 (28%), Positives = 112/248 (45%), Gaps = 8/248 (3%) Frame = +1 Query: 226 GRFGKVFKGRCF---GLEVAVKIPKVQELSP-EQLEKFKQEVAINSEINHPNVVRFLGAC 393 G FG V+ G G ++ + + ++ ++ +F E I + +HPNV+ LG C Sbjct: 1087 GHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGIC 1146 Query: 394 LKPLNFRLVT-EXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDLK 570 L+ LV N+ ++ + + KGM Y+ + VH DL Sbjct: 1147 LRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLA 1206 Query: 571 PENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPL---WMAPEMLLGKPFDEKADI 741 N +LD T K+ADFGL D++ G L WMA E L + F K+D+ Sbjct: 1207 ARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDV 1266 Query: 742 YSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPA 921 +SFG++LW+L+TR I + R P+ L ++ +CWHP+ Sbjct: 1267 WSFGVLLWELMTR-GAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAE 1325 Query: 922 LRPSFTEI 945 +RPSF+E+ Sbjct: 1326 MRPSFSEL 1333
>Q09YL1:MET_ATEGE Hepatocyte growth factor receptor precursor - Ateles geoffroyi| (Black-handed spider monkey) Length = 1381 Score = 103 bits (256), Expect = 3e-21 Identities = 70/248 (28%), Positives = 112/248 (45%), Gaps = 8/248 (3%) Frame = +1 Query: 226 GRFGKVFKGRCF---GLEVAVKIPKVQELSP-EQLEKFKQEVAINSEINHPNVVRFLGAC 393 G FG V+ G G ++ + + ++ ++ +F E I + +HPNV+ LG C Sbjct: 1087 GHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGIC 1146 Query: 394 LKPLNFRLVT-EXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDLK 570 L+ LV N+ ++ + + KGM Y+ + VH DL Sbjct: 1147 LRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLA 1206 Query: 571 PENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPL---WMAPEMLLGKPFDEKADI 741 N +LD T K+ADFGL D++ G L WMA E L + F K+D+ Sbjct: 1207 ARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDV 1266 Query: 742 YSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPA 921 +SFG++LW+L+TR I + R P+ L ++ +CWHP+ Sbjct: 1267 WSFGVLLWELMTR-GAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAE 1325 Query: 922 LRPSFTEI 945 +RPSF+E+ Sbjct: 1326 MRPSFSEL 1333
>Q07DV8:MET_AOTNA Hepatocyte growth factor receptor precursor - Aotus nancymaae (Ma's| night monkey) Length = 1381 Score = 103 bits (256), Expect = 3e-21 Identities = 70/248 (28%), Positives = 112/248 (45%), Gaps = 8/248 (3%) Frame = +1 Query: 226 GRFGKVFKGRCF---GLEVAVKIPKVQELSP-EQLEKFKQEVAINSEINHPNVVRFLGAC 393 G FG V+ G G ++ + + ++ ++ +F E I + +HPNV+ LG C Sbjct: 1087 GHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGIC 1146 Query: 394 LKPLNFRLVT-EXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDLK 570 L+ LV N+ ++ + + KGM Y+ + VH DL Sbjct: 1147 LRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLA 1206 Query: 571 PENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPL---WMAPEMLLGKPFDEKADI 741 N +LD T K+ADFGL D++ G L WMA E L + F K+D+ Sbjct: 1207 ARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDV 1266 Query: 742 YSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPA 921 +SFG++LW+L+TR I + R P+ L ++ +CWHP+ Sbjct: 1267 WSFGVLLWELMTR-GAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAE 1325 Query: 922 LRPSFTEI 945 +RPSF+E+ Sbjct: 1326 MRPSFSEL 1333
>P17713:STK_HYDAT Tyrosine-protein kinase STK - Hydra attenuata (Hydra) (Hydra| vulgaris) Length = 509 Score = 102 bits (255), Expect = 4e-21 Identities = 82/292 (28%), Positives = 129/292 (44%), Gaps = 2/292 (0%) Frame = +1 Query: 133 GVAKGFVGLEIPAEQLIIEEELSKDKDGEDIGRFGKVFKGRCFGL-EVAVKIPKVQELSP 309 G+AK EIP E L + +L G+FG+V+ G +VAVK K +SP Sbjct: 227 GIAKD--AWEIPRESLRLNRKLGA-------GQFGEVWAGVWNNTTQVAVKTLKPGTMSP 277 Query: 310 EQLEKFKQEVAINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSN-KARPLSL 486 F E + ++ H ++V+ C +VTE S + L L Sbjct: 278 AS---FLDEAGVMKKLRHKHLVQLYAICSDREPIYIVTEYMSGGSLLDYLSKGEGVNLQL 334 Query: 487 ARRMRIARDIVKGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHG 666 + +A + GM ++ A +H DL N+L+ N K+ADFGL + D + H Sbjct: 335 PTLIDMAAQVASGMAFLEAQGYIHRDLAARNILVGENYICKVADFGLARLIEDDEYTAHE 394 Query: 667 GPKGTPLWMAPEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNY 846 G K W APE L F K+D++SFGI++ +++T+ I V Y Sbjct: 395 GAKFPIKWTAPEAALYNRFTIKSDVWSFGILMAEIVTKGRIPYPGMTNAQTIAEVE-KGY 453 Query: 847 RPPMPQGTNQKLSYLIHRCWHPQPALRPSFTEIDNAYLQPIIVETAIPDEVG 1002 R P+ G + L ++ + W+ P RP+F YLQ ++ + + E G Sbjct: 454 RMPIMPGCPEPLYNIMLQTWNKDPENRPTFD-----YLQGVLEDYFVSTEQG 500
>Q09YI9:MET_SHEEP Hepatocyte growth factor receptor precursor - Ovis aries (Sheep)| Length = 1384 Score = 102 bits (255), Expect = 4e-21 Identities = 73/250 (29%), Positives = 114/250 (45%), Gaps = 10/250 (4%) Frame = +1 Query: 226 GRFGKVFKGRCFG-----LEVAVK-IPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLG 387 G FG V+ G + AVK + ++ ++ ++ +F E I + +HPNV+ LG Sbjct: 1088 GHFGCVYHGTLLDNDDKKIHCAVKSLNRITDIG--EVSQFLTEGIIMKDFSHPNVLSLLG 1145 Query: 388 ACLKPLNFRLVT-EXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLD 564 CL+ LV N+ ++ + + KGM Y+ + VH D Sbjct: 1146 ICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMEYLASKKFVHRD 1205 Query: 565 LKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPL---WMAPEMLLGKPFDEKA 735 L N +LD T K+ADFGL D++ G L WMA E L + F K+ Sbjct: 1206 LAARNCMLDEKFTVKVADFGLARDVYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKS 1265 Query: 736 DIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQ 915 D++SFG++LW+L+TR I + R P+ L ++ +CWHP+ Sbjct: 1266 DVWSFGVLLWELMTR-GAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPK 1324 Query: 916 PALRPSFTEI 945 LRPSF+E+ Sbjct: 1325 AELRPSFSEL 1334
>Q2QLE0:MET_PIG Hepatocyte growth factor receptor precursor - Sus scrofa (Pig)| Length = 1381 Score = 102 bits (255), Expect = 4e-21 Identities = 73/250 (29%), Positives = 114/250 (45%), Gaps = 10/250 (4%) Frame = +1 Query: 226 GRFGKVFKGRCFG-----LEVAVK-IPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLG 387 G FG V+ G + AVK + ++ ++ ++ +F E I + +HPNV+ LG Sbjct: 1087 GHFGCVYHGTLLDNDDKKIHCAVKSLNRITDIG--EVSQFLTEGIIMKDFSHPNVLSLLG 1144 Query: 388 ACLKPLNFRLVT-EXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLD 564 CL+ LV N+ ++ + + KGM Y+ + VH D Sbjct: 1145 ICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRD 1204 Query: 565 LKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPL---WMAPEMLLGKPFDEKA 735 L N +LD T K+ADFGL D++ G L WMA E L + F K+ Sbjct: 1205 LAARNCMLDEKFTVKVADFGLARDVYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKS 1264 Query: 736 DIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQ 915 D++SFG++LW+L+TR I + R P+ L ++ +CWHP+ Sbjct: 1265 DVWSFGVLLWELMTR-GAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPR 1323 Query: 916 PALRPSFTEI 945 LRPSF+E+ Sbjct: 1324 AELRPSFSEL 1333
>Q09YK0:MET_MUNMU Hepatocyte growth factor receptor precursor - Muntiacus muntjak| (Barking deer) (Indian muntjac) Length = 1382 Score = 102 bits (255), Expect = 4e-21 Identities = 73/250 (29%), Positives = 114/250 (45%), Gaps = 10/250 (4%) Frame = +1 Query: 226 GRFGKVFKGRCFG-----LEVAVK-IPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLG 387 G FG V+ G + AVK + ++ ++ ++ +F E I + +HPNV+ LG Sbjct: 1088 GHFGCVYHGTLLDNDDKKIHCAVKSLNRITDIG--EVSQFLTEGIIMKDFSHPNVLSLLG 1145 Query: 388 ACLKPLNFRLVT-EXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLD 564 CL+ LV N+ ++ + + KGM Y+ + VH D Sbjct: 1146 ICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMEYLASKKFVHRD 1205 Query: 565 LKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPL---WMAPEMLLGKPFDEKA 735 L N +LD T K+ADFGL D++ G L WMA E L + F K+ Sbjct: 1206 LAARNCMLDEKFTVKVADFGLARDVYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKS 1265 Query: 736 DIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQ 915 D++SFG++LW+L+TR I + R P+ L ++ +CWHP+ Sbjct: 1266 DVWSFGVLLWELMTR-GAPPYPDVNTFDITVYLLQGRRLLQPEYCPDALYEVMLKCWHPK 1324 Query: 916 PALRPSFTEI 945 LRPSF+E+ Sbjct: 1325 AELRPSFSEL 1334
>Q769I5:MET_BOVIN Hepatocyte growth factor receptor precursor - Bos taurus (Bovine)| Length = 1384 Score = 102 bits (255), Expect = 4e-21 Identities = 73/250 (29%), Positives = 114/250 (45%), Gaps = 10/250 (4%) Frame = +1 Query: 226 GRFGKVFKGRCFG-----LEVAVK-IPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLG 387 G FG V+ G + AVK + ++ ++ ++ +F E I + +HPNV+ LG Sbjct: 1088 GHFGCVYHGTLLDNDDKKIHCAVKSLNRITDIG--EVSQFLTEGIIMKDFSHPNVLSLLG 1145 Query: 388 ACLKPLNFRLVT-EXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLD 564 CL+ LV N+ ++ + + KGM Y+ + VH D Sbjct: 1146 ICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMEYLASKKFVHRD 1205 Query: 565 LKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPL---WMAPEMLLGKPFDEKA 735 L N +LD T K+ADFGL D++ G L WMA E L + F K+ Sbjct: 1206 LAARNCMLDEKFTVKVADFGLARDVYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKS 1265 Query: 736 DIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQ 915 D++SFG++LW+L+TR I + R P+ L ++ +CWHP+ Sbjct: 1266 DVWSFGVLLWELMTR-GAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPK 1324 Query: 916 PALRPSFTEI 945 LRPSF+E+ Sbjct: 1325 AELRPSFSEL 1334
>Q922K9:FRK_MOUSE Tyrosine-protein kinase FRK - Mus musculus (Mouse)| Length = 512 Score = 102 bits (255), Expect = 4e-21 Identities = 67/242 (27%), Positives = 113/242 (46%), Gaps = 5/242 (2%) Frame = +1 Query: 226 GRFGKVFKGRCFGLE-VAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGACLKP 402 G+FG+V++G VAVK K + P F +E I + HP +++ C Sbjct: 250 GQFGEVWEGLWNNTTPVAVKTLKPGSMDPND---FLREAQIMKSLRHPKLIQLYAVCTLE 306 Query: 403 LNFRLVTEXXXXXXXXXXXSNKA-RPLSLARRMRIARDIVKGMIYIHAANLVHLDLKPEN 579 ++TE N + L +++ +A + GM Y+ + N +H DL N Sbjct: 307 DPIYIITELMRHGSLQEYLQNDGGSKIHLIQQVDMAAQVASGMAYLESQNYIHRDLAARN 366 Query: 580 VLLDFNGTAKIADFGLT-VIRLDRQSLLHGGP--KGTPLWMAPEMLLGKPFDEKADIYSF 750 VL+ + K+ADFGL V ++D + + K W APE + F K+D++SF Sbjct: 367 VLVGEHNIYKVADFGLARVFKVDNEDIYESKHEIKLPVKWTAPEAIRTNKFSIKSDVWSF 426 Query: 751 GIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPALRP 930 GI+L++++T I+ ++ NYR P P Q+ ++ CW+ +P RP Sbjct: 427 GILLYEIITYGKMPYSGMTGAQVIQMLS-QNYRLPQPSNCPQQFYSIMLECWNVEPKQRP 485 Query: 931 SF 936 +F Sbjct: 486 TF 487
>O09127:EPHA8_MOUSE Ephrin type-A receptor 8 precursor - Mus musculus (Mouse)| Length = 1004 Score = 102 bits (255), Expect = 4e-21 Identities = 71/264 (26%), Positives = 116/264 (43%), Gaps = 2/264 (0%) Frame = +1 Query: 160 EIPAEQLIIEEELSKDKDGEDIGRFGKVFKGRCFGLEVAVKIPKVQELSPEQLEKFKQEV 339 EI A ++ IE+ + + GE +G++ + VA+K K + Q + F E Sbjct: 628 EIEASRIHIEKIIGSGESGEVC--YGRLQVPGQRDVPVAIKALKAG-YTERQRQDFLSEA 684 Query: 340 AINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIV 519 AI + +HPN++R G + +VTE ++ + + + R + Sbjct: 685 AIMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDAFLRTHDGQFTIVQLVGMLRGVG 744 Query: 520 KGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLH--GGPKGTPLWM 693 GM Y+ +H DL NVL+D K++DFGL+ D + G K W Sbjct: 745 AGMRYLSDLGYIHRDLAARNVLVDGRLVCKVSDFGLSRALEDDPEAAYTTAGGKIPIRWT 804 Query: 694 APEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTN 873 APE + + F +D++SFG+++W++L I +V YR P P G Sbjct: 805 APEAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNQDVISSVE-EGYRLPAPMGCP 863 Query: 874 QKLSYLIHRCWHPQPALRPSFTEI 945 + L L+ CWH A RP F + Sbjct: 864 RALHQLMLDCWHKDRAQRPRFAHV 887
>Q06187:BTK_HUMAN Tyrosine-protein kinase BTK - Homo sapiens (Human)| Length = 659 Score = 102 bits (255), Expect = 4e-21 Identities = 67/273 (24%), Positives = 124/273 (45%), Gaps = 3/273 (1%) Frame = +1 Query: 127 PFGVAKGFVGLEIPAEQLIIEEELSKDKDGEDIGRFGKVFKGRCFG-LEVAVKIPKVQEL 303 P G+ EI + L +EL G+FG V G+ G +VA+K+ K + Sbjct: 385 PSTAGLGYGSWEIDPKDLTFLKELGT-------GQFGVVKYGKWRGQYDVAIKMIKEGSM 437 Query: 304 SPEQLEKFKQEVAINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNKARPLS 483 S ++ F +E + ++H +V+ G C K ++TE Sbjct: 438 SEDE---FIEEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQ 494 Query: 484 LARRMRIARDIVKGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLH 663 + + + +D+ + M Y+ + +H DL N L++ G K++DFGL+ LD + Sbjct: 495 TQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEYTSS 554 Query: 664 GGPKGTPLWMAPEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVA--I 837 G K W PE+L+ F K+DI++FG+++W++ + + +A + Sbjct: 555 VGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGL 614 Query: 838 NNYRPPMPQGTNQKLSYLIHRCWHPQPALRPSF 936 YRP + ++K+ +++ CWH + RP+F Sbjct: 615 RLYRPHL---ASEKVYTIMYSCWHEKADERPTF 644
>P42689:SRK3_SPOLA Tyrosine-protein kinase SRK3 - Spongilla lacustris (Freshwater| sponge) Length = 334 Score = 102 bits (254), Expect = 5e-21 Identities = 67/245 (27%), Positives = 113/245 (46%), Gaps = 3/245 (1%) Frame = +1 Query: 226 GRFGKVFKGRCFGLEVAVKIPKVQELSPEQLE--KFKQEVAINSEINHPNVVRFLGACLK 399 G FG+V+ G G V+ L P+ +E F QE + +I+HPN+++ C Sbjct: 75 GNFGEVWAGVWNGTTAVA----VKTLKPDTMEVKDFVQEAQVMKKIHHPNLLQLYAVCTI 130 Query: 400 PLNFRLVTEXXXXXXXXXXXSN-KARPLSLARRMRIARDIVKGMIYIHAANLVHLDLKPE 576 +VTE + + + ++L + + ++ I GM Y+ A + +H DL Sbjct: 131 GEPIYIVTELMKYGSMLEYLKHGEGKNITLHQMVDMSAQIASGMTYLEAHSYIHRDLAAR 190 Query: 577 NVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWMAPEMLLGKPFDEKADIYSFGI 756 N+L+ K+ADFGL + + G K W APE L F K+D++SFG+ Sbjct: 191 NILVGEGNVCKVADFGLARVIKEDIYNPREGTKFPIKWTAPEAALYNRFTIKSDVWSFGV 250 Query: 757 ILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPALRPSF 936 ++ +++T ++AV YR P P+G L ++ CW +P RP+F Sbjct: 251 LISEIVTHGRMPYPGMTNRQVLEAVD-RGYRMPCPEGCPDPLYKIMLSCWKHEPDDRPTF 309 Query: 937 TEIDN 951 + N Sbjct: 310 ESLKN 314
>Q2IBC0:MET_RHIFE Hepatocyte growth factor receptor precursor - Rhinolophus| ferrumequinum (Greater horseshoe bat) Length = 1381 Score = 102 bits (254), Expect = 5e-21 Identities = 73/250 (29%), Positives = 113/250 (45%), Gaps = 10/250 (4%) Frame = +1 Query: 226 GRFGKVFKGRCFG-----LEVAVK-IPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLG 387 G FG V+ G + AVK + ++ ++ ++ +F E I + +HPNV+ LG Sbjct: 1087 GHFGCVYHGTLLDNDDKKIHCAVKSLNRITDIG--EVSQFLTEGIIMKDFSHPNVLSLLG 1144 Query: 388 ACLKPLNFRLVT-EXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLD 564 CL+ LV N+ ++ + + KGM Y+ + VH D Sbjct: 1145 ICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRD 1204 Query: 565 LKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPL---WMAPEMLLGKPFDEKA 735 L N +LD N T K+ADFGL D++ G L WMA E L + F K+ Sbjct: 1205 LAARNCMLDENFTVKVADFGLARDVYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKS 1264 Query: 736 DIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQ 915 D++SFG++LW+L+TR I + R P+ L ++ +CWHP+ Sbjct: 1265 DVWSFGVLLWELMTR-GAPPYPDVNTFDITVYLLQGRRLLQPEYCPDHLYEVMLKCWHPK 1323 Query: 916 PALRPSFTEI 945 RPSF E+ Sbjct: 1324 AEQRPSFAEL 1333
>P97523:MET_RAT Hepatocyte growth factor receptor precursor - Rattus norvegicus (Rat)| Length = 1382 Score = 102 bits (254), Expect = 5e-21 Identities = 70/248 (28%), Positives = 112/248 (45%), Gaps = 8/248 (3%) Frame = +1 Query: 226 GRFGKVFKGRCF---GLEVAVKIPKVQELSP-EQLEKFKQEVAINSEINHPNVVRFLGAC 393 G FG V+ G G ++ + + ++ E++ +F E I + +HPNV+ LG C Sbjct: 1088 GHFGCVYHGTLLDSDGKKIHCAVKSLNRITDIEEVSQFLTEGIIMKDFSHPNVLSLLGIC 1147 Query: 394 LKPLNFRLVT-EXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDLK 570 L+ LV N+ ++ + + KGM Y+ + VH DL Sbjct: 1148 LRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLVSKKFVHRDLA 1207 Query: 571 PENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPL---WMAPEMLLGKPFDEKADI 741 N +LD T K+ADFGL D++ G L WMA E L + F K+D+ Sbjct: 1208 ARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDV 1267 Query: 742 YSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPA 921 +SFG++LW+L+TR I + R P+ L ++ +CWHP+ Sbjct: 1268 WSFGVLLWELMTR-GAPPYPDVNTFDITIYLLQGRRLLQPEYCPDALYEVMLKCWHPKAE 1326 Query: 922 LRPSFTEI 945 +RPS +E+ Sbjct: 1327 MRPSVSEL 1334
>P14617:INSRR_CAVPO Insulin receptor-related protein precursor - Cavia porcellus (Guinea| pig) Length = 1300 Score = 102 bits (254), Expect = 5e-21 Identities = 83/281 (29%), Positives = 125/281 (44%), Gaps = 16/281 (5%) Frame = +1 Query: 160 EIPAEQLIIEEELSKDKDGEDIGRFGKVFKGRCFGLEVA-----VKIPKVQEL-SPEQLE 321 E+P EQ+ I EL + G FG V++G GLE V + V EL SP + Sbjct: 973 EVPREQISIIRELGQ-------GSFGMVYEGVAKGLEAGEESTPVALKTVNELASPRERI 1025 Query: 322 KFKQEVAINSEINHPNVVRFLGAC--------LKPLNFRLVTEXXXXXXXXXXXSNKARP 477 +F +E ++ +VVR LG + L R + +N P Sbjct: 1026 EFLKEASVMKAFQCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSHLRSLRPEAENNPGIP 1085 Query: 478 L-SLARRMRIARDIVKGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQS 654 +L +++A +I GM Y+ A VH DL N ++ + T KI DFG+T + Sbjct: 1086 RPALGDMIQMAGEIADGMAYLAANKFVHRDLAARNCMVSQDFTVKIGDFGMTRDVYETDY 1145 Query: 655 LLHGGPKGTPL-WMAPEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAV 831 GG P+ WMAPE L F +D++SFG++LW+++T +K V Sbjct: 1146 YRKGGKGLLPVRWMAPESLKDGIFTTHSDVWSFGVVLWEIVTLAEQPYQGLSNEQVLKFV 1205 Query: 832 AINNYRPPMPQGTNQKLSYLIHRCWHPQPALRPSFTEIDNA 954 + +Q L L+ CW P LRP+FT+I N+ Sbjct: 1206 MDGGVLEELEDCPHQ-LQELMSSCWQQNPRLRPTFTQILNS 1245
>Q07497:EPHB5_CHICK Ephrin type-B receptor 5 precursor - Gallus gallus (Chicken)| Length = 1002 Score = 102 bits (254), Expect = 5e-21 Identities = 73/256 (28%), Positives = 113/256 (44%), Gaps = 13/256 (5%) Frame = +1 Query: 226 GRFGKVFKGRCFG---------LEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVR 378 G FG+V CFG VA+K K + EQ +F E +I + HPNV+ Sbjct: 646 GEFGEV----CFGRLKHPGKREYTVAIKTLK-SGYTDEQRREFLSEASIMGQFEHPNVIH 700 Query: 379 FLGACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVH 558 G K +VTE K S+ + + + R I GM Y+ N VH Sbjct: 701 LEGVVTKSRPVMIVTEFMENGSLDSFLRQKEGQFSVLQLVGMLRGIAAGMRYLSDMNYVH 760 Query: 559 LDLKPENVLLDFNGTAKIADFGLT-VIRLDRQSLLHGGPKGTPL---WMAPEMLLGKPFD 726 DL N+L++ N K++DFGL+ + D + + G G + W APE + + F Sbjct: 761 RDLAARNILVNSNLVCKVSDFGLSRFLEDDASNPTYTGALGCKIPIRWTAPEAVQYRKFT 820 Query: 727 EKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCW 906 +D++S+GI++W++++ I A+ +YR P P L L+ CW Sbjct: 821 SSSDVWSYGIVMWEVMSYGERPYWDMSNQDVINAID-QDYRLPPPPDCPTVLHLLMLDCW 879 Query: 907 HPQPALRPSFTEIDNA 954 RP F +I +A Sbjct: 880 QKDRVQRPKFEQIVSA 895
>Q61006:MUSK_MOUSE Muscle, skeletal receptor tyrosine protein kinase precursor - Mus| musculus (Mouse) Length = 868 Score = 102 bits (253), Expect = 7e-21 Identities = 79/271 (29%), Positives = 119/271 (43%), Gaps = 31/271 (11%) Frame = +1 Query: 226 GRFGKVFKGRCFGL-------EVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFL 384 G FG+VF+ R GL VAVK+ K +E S + F++E A+ +E ++PN+V+ L Sbjct: 583 GAFGRVFQARAPGLLPYEPFTMVAVKMLK-EEASADMQADFQREAALMAEFDNPNIVKLL 641 Query: 385 GACL--KPLNF--------------RLVTEXXXXXXXXXXXSNKAR-------PLSLARR 495 G C KP+ R ++ S +AR PLS A + Sbjct: 642 GVCAVGKPMCLLFEYMAYGDLNEFLRSMSPHTVCSLSHSDLSTRARVSSPGPPPLSCAEQ 701 Query: 496 MRIARDIVKGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPK 675 + IAR + GM Y+ VH DL N L+ KIADFGL+ G Sbjct: 702 LCIARQVAAGMAYLSERKFVHRDLATRNCLVGETMVVKIADFGLSRNIYSADYYKADGND 761 Query: 676 GTPL-WMAPEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRP 852 P+ WM PE + + ++D++++G++LW++ + I V N Sbjct: 762 AIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNIL- 820 Query: 853 PMPQGTNQKLSYLIHRCWHPQPALRPSFTEI 945 P+ +L L+ CW PA RPSF I Sbjct: 821 ACPENCPLELYNLMRLCWSKLPADRPSFCSI 851
>Q108U6:MET_LOXAF Hepatocyte growth factor receptor precursor - Loxodonta africana| (African elephant) Length = 1382 Score = 102 bits (253), Expect = 7e-21 Identities = 72/250 (28%), Positives = 114/250 (45%), Gaps = 10/250 (4%) Frame = +1 Query: 226 GRFGKVFKGRCFG-----LEVAVK-IPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLG 387 G FG V+ G + AVK + ++ ++ ++ +F E I + +HPNV+ LG Sbjct: 1088 GHFGCVYHGTLLDNGDKKIHCAVKSLNRITDIG--EVSQFLTEGIIMKDFSHPNVLSLLG 1145 Query: 388 ACLKPLNFRLVT-EXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLD 564 CL+ LV N+ ++ + + KGM Y+ + VH D Sbjct: 1146 ICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRD 1205 Query: 565 LKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPL---WMAPEMLLGKPFDEKA 735 L N +LD T K+ADFGL D++ G L WMA E L + F K+ Sbjct: 1206 LAARNCMLDEKFTVKVADFGLARDVYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKS 1265 Query: 736 DIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQ 915 D++SFG++LW+L+TR I + R P+ L ++ +CWHP+ Sbjct: 1266 DVWSFGVLLWELMTR-GAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPK 1324 Query: 916 PALRPSFTEI 945 +RPSF+E+ Sbjct: 1325 AEMRPSFSEL 1334
>P41243:MATK_RAT Megakaryocyte-associated tyrosine-protein kinase - Rattus| norvegicus (Rat) Length = 467 Score = 102 bits (253), Expect = 7e-21 Identities = 72/241 (29%), Positives = 112/241 (46%), Gaps = 1/241 (0%) Frame = +1 Query: 226 GRFGKVFKGRCFGLEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGACLKPL 405 G FG V +G G +VAVK K + + F E A+ +++ H N+VR LG L Sbjct: 203 GEFGAVLQGEYLGQKVAVKNIKCDVTA----QAFLDETAVMTKLQHRNLVRLLGVILHH- 257 Query: 406 NFRLVTEXXXXXXXXXXXSNKARPL-SLARRMRIARDIVKGMIYIHAANLVHLDLKPENV 582 +V E + R L S ++ ++ A + +GM Y+ + LVH DL N+ Sbjct: 258 GLYIVMEHVSKGNLVNFLRTRGRALVSTSQLLQFALHVAEGMEYLESKKLVHRDLAARNI 317 Query: 583 LLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWMAPEMLLGKPFDEKADIYSFGIIL 762 L+ + AK++DFGL L R+ L + W APE L F K+D++SFG++L Sbjct: 318 LVSEDLVAKVSDFGLAKAEL-RKGL--DSSRLPVKWTAPEALKNGRFSSKSDVWSFGVLL 374 Query: 763 WQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPALRPSFTE 942 W++ + +AV YR P + L+ CW +P+ RP F + Sbjct: 375 WEVFSYGRAPYPKMSLKEVSEAVE-KGYRMEPPDSCPGPVHTLMGSCWEAEPSRRPPFRK 433 Query: 943 I 945 I Sbjct: 434 I 434 Score = 39.7 bits (91), Expect = 0.043 Identities = 21/58 (36%), Positives = 29/58 (50%) Frame = +1 Query: 1417 PWFYGDLDKDAAFELLRNKQPGTFLVRFSSNPEHVGFVISVVDHKNTVVHIRVKHNAG 1590 PWF+G + A + L+ + G FLVR S+ H G + V V+H RV H G Sbjct: 80 PWFHGKISGQEAIQQLQPPEDGLFLVRESA--RHPGDYVLCVSFGRDVIHYRVLHRDG 135
>P54757:EPHA5_RAT Ephrin type-A receptor 5 precursor - Rattus norvegicus (Rat)| Length = 1005 Score = 102 bits (253), Expect = 7e-21 Identities = 77/273 (28%), Positives = 116/273 (42%), Gaps = 7/273 (2%) Frame = +1 Query: 154 GLEIPAEQLIIEEELSKDKDGEDIGRFGKVFKGRCF-----GLEVAVKIPKVQELSPEQL 318 G EI A + IE + G FG+V GR L VA K KV + +Q Sbjct: 669 GKEIEASCITIERVIGA-------GEFGEVCSGRLKLPGKRELPVATKTLKVG-YTEKQR 720 Query: 319 EKFKQEVAINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRM 498 F E +I + +HPN++ G K +VTE ++ + + Sbjct: 721 RDFLSEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLV 780 Query: 499 RIARDIVKGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLH--GGP 672 + R I GM Y+ VH DL N+L++ N K++DFGL+ + D + G Sbjct: 781 GMLRGIAAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGG 840 Query: 673 KGTPLWMAPEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRP 852 K W APE + + F +D++S+GI++W++++ IKAV YR Sbjct: 841 KIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVE-EGYRL 899 Query: 853 PMPQGTNQKLSYLIHRCWHPQPALRPSFTEIDN 951 P P L L+ CW RP F +I N Sbjct: 900 PSPMDCPAALYQLMLDCWQKDRNSRPKFDDIVN 932
>P54756:EPHA5_HUMAN Ephrin type-A receptor 5 precursor - Homo sapiens (Human)| Length = 1037 Score = 102 bits (253), Expect = 7e-21 Identities = 72/249 (28%), Positives = 110/249 (44%), Gaps = 7/249 (2%) Frame = +1 Query: 226 GRFGKVFKGRCF-----GLEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGA 390 G FG+V GR L VA+K KV + +Q F E +I + +HPN++ G Sbjct: 684 GEFGEVCSGRLKLPGKRELPVAIKTLKVG-YTEKQRRDFLGEASIMGQFDHPNIIHLEGV 742 Query: 391 CLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDLK 570 K +VTE ++ + + + R I GM Y+ VH DL Sbjct: 743 VTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGYVHRDLA 802 Query: 571 PENVLLDFNGTAKIADFGLTVIRLDRQSLLH--GGPKGTPLWMAPEMLLGKPFDEKADIY 744 N+L++ N K++DFGL+ + D + G K W APE + + F +D++ Sbjct: 803 ARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDVW 862 Query: 745 SFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPAL 924 S+GI++W++++ IKAV YR P P L L+ CW + Sbjct: 863 SYGIVMWEVVSYGERPYWEMTNQDVIKAVE-EGYRLPSPMDCPAALYQLMLDCWQKERNS 921 Query: 925 RPSFTEIDN 951 RP F EI N Sbjct: 922 RPKFDEIVN 930
>Q03145:EPHA2_MOUSE Ephrin type-A receptor 2 precursor - Mus musculus (Mouse)| Length = 977 Score = 102 bits (253), Expect = 7e-21 Identities = 65/248 (26%), Positives = 114/248 (45%), Gaps = 8/248 (3%) Frame = +1 Query: 226 GRFGKVFKGRCFG------LEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLG 387 G FG+V+KG + VA+K K ++++ F E +I + +H N++ G Sbjct: 623 GEFGEVYKGTLKASSGKKEIPVAIKTLKAGYTEKQRVD-FLSEASIMGQFSHHNIIPLEG 681 Query: 388 ACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDL 567 K ++TE K S+ + + + R I GM Y+ N VH DL Sbjct: 682 VVSKYKPMMIITEYMENGALDKFLREKDGEFSVLQLVGMLRGIASGMKYLANMNYVHRDL 741 Query: 568 KPENVLLDFNGTAKIADFGLTVIRLDRQSLLH--GGPKGTPLWMAPEMLLGKPFDEKADI 741 N+L++ N K++DFGL+ + D + G K W APE + + F +D+ Sbjct: 742 AARNILVNSNLVCKVSDFGLSRVLEDDPEATYTTSGGKIPIRWTAPEAISYRKFTSASDV 801 Query: 742 YSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPA 921 +S+GI++W+++T +KA+ + +R P P + L+ +CW + + Sbjct: 802 WSYGIVMWEVMTYGERPYWELSNHEVMKAIN-DGFRLPTPMDCPSAIYQLMMQCWQQERS 860 Query: 922 LRPSFTEI 945 RP F +I Sbjct: 861 RRPKFADI 868
>Q91571:EPB1A_XENLA Ephrin type-B receptor 1-A precursor - Xenopus laevis (African clawed| frog) Length = 985 Score = 102 bits (253), Expect = 7e-21 Identities = 73/258 (28%), Positives = 114/258 (44%), Gaps = 9/258 (3%) Frame = +1 Query: 226 GRFGKVFKGRCF-----GLEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGA 390 G FG+V+KGR + VA+K K S +Q F E +I + +HPN++R G Sbjct: 629 GEFGEVYKGRLKLPSKREISVAIKTLKAG-YSEKQRRDFLSEASIMGQFDHPNIIRLEGV 687 Query: 391 CLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDLK 570 K ++TE ++ + + + R I GM Y+ N VH DL Sbjct: 688 VTKSRPVMIITEFMENGALDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLA 747 Query: 571 PENVLLDFNGTAKIADFGLTVIRLDRQS----LLHGGPKGTPLWMAPEMLLGKPFDEKAD 738 N+L++ N K++DFGL+ D S G K W A E + + F +D Sbjct: 748 ARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVRWTAQEAIAYRKFTSASD 807 Query: 739 IYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQP 918 ++S+GI++W++++ I A+ +YR P P L L+ CW Sbjct: 808 VWSYGIVMWEVMSYGERPYWTMSNQDVINAIE-QDYRLPPPMDCPAALHQLMLDCWQKDR 866 Query: 919 ALRPSFTEIDNAYLQPII 972 RP EI N L+P+I Sbjct: 867 NSRPRLAEIVNT-LRPMI 883
>P08630:BTKL_DROME Tyrosine-protein kinase Btk29A - Drosophila melanogaster (Fruit fly)| Length = 786 Score = 102 bits (253), Expect = 7e-21 Identities = 74/282 (26%), Positives = 124/282 (43%), Gaps = 3/282 (1%) Frame = +1 Query: 100 PGTGAAIHDPFGVAKGFVGLEIPAEQLIIEEELSKDKDGEDIGRFGKVFKGRCFG-LEVA 276 P T HD + EI +L++ EEL G+FG V +G+ G ++ A Sbjct: 509 PPTAGLSHDKW---------EIHPMELMLMEELGS-------GQFGVVRRGKWRGSIDTA 552 Query: 277 VKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXX 456 VK+ K +S + F +E + +++ HPN+V+ G C K +VTE Sbjct: 553 VKMMKEGTMSEDD---FIEEAKVMTKLQHPNLVQLYGVCSKHRPIYIVTEYMKHGSLLNY 609 Query: 457 XSNKARPL--SLARRMRIARDIVKGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLT 630 + L ++ + + + KGM Y+ N +H DL N L+ K+ADFGL Sbjct: 610 LRRHEKTLIGNMGLLLDMCIQVSKGMTYLERHNYIHRDLAARNCLVGSENVVKVADFGLA 669 Query: 631 VIRLDRQSLLHGGPKGTPLWMAPEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXX 810 LD Q GG K W PE+L F K+D++++G+++W++ T Sbjct: 670 RYVLDDQYTSSGGTKFPIKWAPPEVLNYTRFSSKSDVWAYGVLMWEIFTCGKMPYGRLKN 729 Query: 811 XXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPALRPSF 936 ++ V P+ +++ ++ CW P RP+F Sbjct: 730 TEVVERVQ-RGIILEKPKSCAKEIYDVMKLCWSHGPEERPAF 770
>Q15569:TESK1_HUMAN Dual specificity testis-specific protein kinase 1 - Homo sapiens| (Human) Length = 626 Score = 101 bits (252), Expect = 9e-21 Identities = 85/308 (27%), Positives = 137/308 (44%), Gaps = 22/308 (7%) Frame = +1 Query: 88 PSAGPGT--GAAIHDPFGVAKGFVGLEIPAEQLIIEEELSKDKDGEDI--------GRFG 237 P GPG G P G G G P+ ++ +S +D G F Sbjct: 11 PGPGPGEVPGEGPPGPGGTGGG-PGRGRPSSYRVLRSAVSSLARVDDFHCAEKIGAGFFS 69 Query: 238 KVFK--GRCFGLEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGACLKPLNF 411 +V+K R G + +K+ K+ P +EV + + + HPN++RF+G C+ Sbjct: 70 EVYKVRHRQSGQVMVLKMNKL----PSNRGNTLREVQLMNRLRHPNILRFMGVCVHQGQL 125 Query: 412 RLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDLKPENVLL- 588 +TE S+ PLS R+ +A DI +G+ Y+H+ + H DL +N L+ Sbjct: 126 HALTEYMNGGTLEQLLSSP-EPLSWPVRLHLALDIARGLRYLHSKGVFHRDLTSKNCLVR 184 Query: 589 --DFNGTAKIADFGLTVIRLDRQSLLHGGPK-------GTPLWMAPEMLLGKPFDEKADI 741 D TA + DFGL ++ + G + G+P WMAPE+L G+ +DEKAD+ Sbjct: 185 REDRGFTAVVGDFGLA----EKIPVYREGARKEPLAVVGSPYWMAPEVLRGELYDEKADV 240 Query: 742 YSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPA 921 ++FGI+L +L+ R + + +R + L C + +P+ Sbjct: 241 FAFGIVLCELIARVPADPDYLPRTEDF-GLDVPAFRTLVGDDCPLPFLLLAIHCCNLEPS 299 Query: 922 LRPSFTEI 945 R FTEI Sbjct: 300 TRAPFTEI 307
>P53670:LIMK2_RAT LIM domain kinase 2 - Rattus norvegicus (Rat)| Length = 638 Score = 101 bits (252), Expect = 9e-21 Identities = 73/282 (25%), Positives = 126/282 (44%), Gaps = 23/282 (8%) Frame = +1 Query: 214 GEDIGR--FGKVFKGRCFGLEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLG 387 GE +G+ FG+ K + + ++ E + F EV + ++HPNV++F+G Sbjct: 334 GEVLGKGFFGQAIKVTHKATGKVMVMKELIRCDEETQKTFLTEVKVMRSLDHPNVLKFIG 393 Query: 388 ACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDL 567 K L+TE N P +++R A+ I GM Y+H+ ++H DL Sbjct: 394 VLYKDKKLNLLTEYIEGGTLKDFLRN-VDPFPWQQKVRFAKGIASGMAYLHSMCIIHRDL 452 Query: 568 KPENVLLDFNGTAKIADFGLTVIRLD-------------RQSLLHGGPK------GTPLW 690 N L+ + T +ADFGL+ + ++ +++L K G P W Sbjct: 453 NSHNCLIKLDKTVVVADFGLSRLIVEERKRPPVEKAATKKRTLRKSDRKKRYTVVGNPYW 512 Query: 691 MAPEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGT 870 MAPEML GK +DE D++SFGI+L +++ + + +P Sbjct: 513 MAPEMLNGKSYDETVDVFSFGIVLCEIIGQVYADPDCLPRTLDFGLNVKLFWEKFVPTDC 572 Query: 871 NQKLSYLIHRCWHPQPALRPSFTEIDNAY--LQPIIVETAIP 990 L C +P RP+F+++++++ L + E AIP Sbjct: 573 PPAFFPLAAICCKLEPESRPAFSKLEDSFEALSLFLGELAIP 614
>Q61UC4:KRAF1_CAEBR Raf homolog serine/threonine-protein kinase - Caenorhabditis briggsae| Length = 811 Score = 101 bits (252), Expect = 9e-21 Identities = 81/298 (27%), Positives = 136/298 (45%), Gaps = 15/298 (5%) Frame = +1 Query: 226 GRFGKVFKGRCFGLEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGACLKPL 405 G FG V++G FG VA+K V + +P Q+ FK EVA+ + H NV+ F+G +P Sbjct: 488 GSFGTVYRGEFFGT-VAIKKLNVVDPTPSQMAAFKNEVAVLKKTRHLNVLLFMGWVREP- 545 Query: 406 NFRLVTE--XXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDLKPEN 579 ++T+ ++ + I + + GM Y+H+ N++H DLK N Sbjct: 546 EIAIITQWCEGSSLYRHIHVQEPRVEFEMSAVIDILKQVSLGMNYLHSKNIIHRDLKTNN 605 Query: 580 V-LLDFNGTAKIADFGLTVIRLDRQSLLHGG-----PKGTPLWMAPEMLL---GKPFDEK 732 + L+D T KI DFGL ++ + ++GG P G+ LWMAPE++ P+ + Sbjct: 606 IFLMDDMSTVKIGDFGLATVK--TKWTVNGGQQQQQPTGSILWMAPEVIRMQDDNPYTPQ 663 Query: 733 ADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQ---GTNQKLSYLIHRC 903 +D+YSFG+ ++++L+ + V +P + T + L L C Sbjct: 664 SDVYSFGVCMYEILSSHLPYSNINNRDQILFMVGRGYLKPDRSKIRTDTPKSLMKLYDNC 723 Query: 904 WHPQPALRPSFTEIDNAYLQPIIVETAIPDEVGRVL-WKNHFLNLDAVNWEQFVMAFY 1074 RP F E+ I+ + VL + + + +DAV Q V + Y Sbjct: 724 IMFDRNERPVFGEVLERLRDIILPKLTRSQSAPNVLHYDSQYSVMDAVMRSQMVSSSY 781
>O08680:EPHA3_RAT Ephrin type-A receptor 3 precursor - Rattus norvegicus (Rat)| Length = 984 Score = 101 bits (252), Expect = 9e-21 Identities = 74/266 (27%), Positives = 116/266 (43%), Gaps = 15/266 (5%) Frame = +1 Query: 193 ELSKDKDGEDI--------GRFGKVFKGRCF-----GLEVAVKIPKVQELSPEQLEKFKQ 333 E +K+ D +I G FG+V GR + VA+K KV + +Q F Sbjct: 612 EFAKELDATNIAIDKVVGAGEFGEVCSGRLKLPSKKEISVAIKTLKVG-YTEKQRRDFLG 670 Query: 334 EVAINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARD 513 E +I + +HPN++R G K +VTE ++ + + + R Sbjct: 671 EASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLRKHDAQFTVIQLVGMLRG 730 Query: 514 IVKGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLH--GGPKGTPL 687 I GM Y+ VH DL N+L++ N K++DFGL+ + D + G K Sbjct: 731 IASGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPVR 790 Query: 688 WMAPEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQG 867 W +PE + F +D++S+GI+LW++++ IKAV YR P+P Sbjct: 791 WTSPEATAYRKFTSASDVWSYGIVLWEVMSYGERPYWEMSNQDVIKAVD-EGYRLPLPMD 849 Query: 868 TNQKLSYLIHRCWHPQPALRPSFTEI 945 L L+ CW RP F +I Sbjct: 850 CPAALYQLMLDCWQKDRNNRPKFEQI 875
>Q9LDQ3:CRK35_ARATH Putative cysteine-rich receptor-like protein kinase 35 precursor -| Arabidopsis thaliana (Mouse-ear cress) Length = 669 Score = 101 bits (252), Expect = 9e-21 Identities = 70/207 (33%), Positives = 110/207 (53%), Gaps = 9/207 (4%) Frame = +1 Query: 184 IEEELSKDKDGEDIGR--FGKVFKGRCF-GLEVAVKIPKVQELSPEQLEKFKQEVAINSE 354 IE K D IGR FG+V++G+ G EVAVK ++ + S + E+FK E + S+ Sbjct: 338 IEAATDKFSDSNMIGRGGFGEVYRGKLSSGPEVAVK--RLSKTSGQGAEEFKNEAVLVSK 395 Query: 355 INHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNKAR--PLSLARRMRIARDIVKGM 528 + H N+VR LG CL+ LV E + A+ L RR I I +G+ Sbjct: 396 LQHKNLVRLLGFCLEGEEKILVYEFVPNKSLDYFLFDPAKQGELDWTRRYNIIGGIARGI 455 Query: 529 IYIH---AANLVHLDLKPENVLLDFNGTAKIADFGLT-VIRLDRQSLLHGGPKGTPLWMA 696 +Y+H ++H DLK N+LLD + KIADFG+ + +D+ GT +M+ Sbjct: 456 LYLHQDSRLTIIHRDLKASNILLDADMNPKIADFGMARIFGVDQSQANTRRIAGTFGYMS 515 Query: 697 PEMLLGKPFDEKADIYSFGIILWQLLT 777 PE + F K+D+YSFG+++ ++++ Sbjct: 516 PEYAMRGHFSMKSDVYSFGVLVLEIIS 542
>P35991:BTK_MOUSE Tyrosine-protein kinase BTK - Mus musculus (Mouse)| Length = 659 Score = 101 bits (252), Expect = 9e-21 Identities = 66/273 (24%), Positives = 124/273 (45%), Gaps = 3/273 (1%) Frame = +1 Query: 127 PFGVAKGFVGLEIPAEQLIIEEELSKDKDGEDIGRFGKVFKGRCFG-LEVAVKIPKVQEL 303 P G+ EI + L +EL G+FG V G+ G +VA+K+ + + Sbjct: 385 PSTAGLGYGSWEIDPKDLTFLKELGT-------GQFGVVKYGKWRGQYDVAIKMIREGSM 437 Query: 304 SPEQLEKFKQEVAINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNKARPLS 483 S ++ F +E + ++H +V+ G C K ++TE Sbjct: 438 SEDE---FIEEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQ 494 Query: 484 LARRMRIARDIVKGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLH 663 + + + +D+ + M Y+ + +H DL N L++ G K++DFGL+ LD + Sbjct: 495 TQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEYTSS 554 Query: 664 GGPKGTPLWMAPEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVA--I 837 G K W PE+L+ F K+DI++FG+++W++ + + +A + Sbjct: 555 VGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGL 614 Query: 838 NNYRPPMPQGTNQKLSYLIHRCWHPQPALRPSF 936 YRP + ++++ +++ CWH + RPSF Sbjct: 615 RLYRPHL---ASERVYTIMYSCWHEKADERPSF 644
>P97793:ALK_MOUSE ALK tyrosine kinase receptor precursor - Mus musculus (Mouse)| Length = 1621 Score = 101 bits (252), Expect = 9e-21 Identities = 83/284 (29%), Positives = 126/284 (44%), Gaps = 22/284 (7%) Frame = +1 Query: 226 GRFGKVFKGRCFG-------LEVAVKIPKVQELSPEQLE-KFKQEVAINSEINHPNVVRF 381 G FG+V++G+ G L+VAVK + E+ EQ E F E I S+ NH N+VR Sbjct: 1129 GAFGEVYEGQVSGMPNDPSPLQVAVKT--LPEVCSEQDELDFLMEALIISKFNHQNIVRC 1186 Query: 382 LGACLKPL-NFRLVTEXXXXXXXXXXXSNKARP-----LSLARRMRIARDIVKGMIYIHA 543 +G L+ L F L+ + RP L++ + +ARDI G Y+ Sbjct: 1187 IGVSLQALPRFILLELMAGGDLKSFLRETRPRPNQPTSLAMLDLLHVARDIACGCQYLEE 1246 Query: 544 ANLVHLDLKPENVLLDFNGT---AKIADFGLTVIRLDRQSLLHGGPKGTPL-WMAPEMLL 711 + +H D+ N LL G AKI DFG+ GG P+ WM PE + Sbjct: 1247 NHFIHRDIAARNCLLTCPGAGRIAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFM 1306 Query: 712 GKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYL 891 F K D +SFG++LW++ + ++ V P P+ + + Sbjct: 1307 EGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDP-PKNCPGPVYRI 1365 Query: 892 IHRCWHPQPALRPSFT----EIDNAYLQPIIVETAIPDEVGRVL 1011 + +CW QP RP+F I+ P ++ TA+P E G V+ Sbjct: 1366 MTQCWQHQPEDRPNFAIILERIEYCTQDPDVINTALPIEYGPVV 1409
>Q62662:FRK_RAT Tyrosine-protein kinase FRK - Rattus norvegicus (Rat)| Length = 506 Score = 101 bits (251), Expect = 1e-20 Identities = 66/242 (27%), Positives = 111/242 (45%), Gaps = 5/242 (2%) Frame = +1 Query: 226 GRFGKVFKGRCFGLE-VAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGACLKP 402 G+FG+V++G VAVK K + P F +E I + HP +++ C Sbjct: 244 GQFGEVWEGLWNNTTPVAVKTLKPGSMDPND---FLREAQIMKSLRHPKLIQLYAVCTLE 300 Query: 403 LNFRLVTEXXXXXXXXXXXSNKA-RPLSLARRMRIARDIVKGMIYIHAANLVHLDLKPEN 579 ++TE N + L +++ +A + GM Y+ + N +H DL N Sbjct: 301 DPIYIITELMRHGSLQEYLQNDGGSKIRLTQQVDMAAQVASGMAYLESQNYIHRDLAARN 360 Query: 580 VLLDFNGTAKIADFGLT-VIRLDRQSLLHGGP--KGTPLWMAPEMLLGKPFDEKADIYSF 750 VL+ + K+ADFGL V ++D + + K W APE + F K+D++SF Sbjct: 361 VLVGEHNIYKVADFGLARVFKVDNEDIYESKHEIKLPVKWTAPEAIRTNKFSIKSDVWSF 420 Query: 751 GIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPALRP 930 GI+L++++T I + NYR P P ++ ++ CW+ +P RP Sbjct: 421 GILLYEIITYGKMPYSGMTGAQVIHMLG-QNYRLPQPSNCPEQFYSIMMECWNVEPKQRP 479 Query: 931 SF 936 +F Sbjct: 480 TF 481
>Q8H199:CRK14_ARATH Cysteine-rich receptor-like protein kinase 14 precursor -| Arabidopsis thaliana (Mouse-ear cress) Length = 658 Score = 101 bits (251), Expect = 1e-20 Identities = 66/205 (32%), Positives = 108/205 (52%), Gaps = 8/205 (3%) Frame = +1 Query: 184 IEEELSKDKDGEDIGR--FGKVFKGRCFGLEVAVKIPKVQELSPEQLEKFKQEVAINSEI 357 IE+ +K + IGR FG+VF G G EVA+K ++ + S + +FK EV + +++ Sbjct: 330 IEDATNKFSESNIIGRGGFGEVFMGVLNGTEVAIK--RLSKASRQGAREFKNEVVVVAKL 387 Query: 358 NHPNVVRFLGACLKPLNFRLVTE--XXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMI 531 +H N+V+ LG CL+ LV E K L +R I R I +G++ Sbjct: 388 HHRNLVKLLGFCLEGEEKILVYEFVPNKSLDYFLFDPTKQGQLDWTKRYNIIRGITRGIL 447 Query: 532 YIH---AANLVHLDLKPENVLLDFNGTAKIADFGLT-VIRLDRQSLLHGGPKGTPLWMAP 699 Y+H ++H DLK N+LLD + KIADFG+ + +D+ GT +M P Sbjct: 448 YLHQDSRLTIIHRDLKASNILLDADMNPKIADFGMARIFGIDQSGANTKKIAGTRGYMPP 507 Query: 700 EMLLGKPFDEKADIYSFGIILWQLL 774 E + F ++D+YSFG+++ +++ Sbjct: 508 EYVRQGQFSTRSDVYSFGVLVLEII 532
>P13388:XMRK_XIPMA Melanoma receptor tyrosine-protein kinase precursor - Xiphophorus| maculatus (Southern platyfish) Length = 1167 Score = 100 bits (250), Expect = 2e-20 Identities = 76/270 (28%), Positives = 123/270 (45%), Gaps = 7/270 (2%) Frame = +1 Query: 175 QLIIEEELSKDKDGEDIGRFGKVFKG------RCFGLEVAVKIPKVQELSPEQLEKFKQE 336 +++ E E KD+ G FG V+KG + VA+K+ + + SP+ ++ E Sbjct: 703 RILKETEFKKDRVLGS-GAFGTVYKGLWNPDGENIRIPVAIKVLR-EATSPKVNQEVLDE 760 Query: 337 VAINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDI 516 + + ++HP+V R LG CL +LVT+ + + I Sbjct: 761 AYVMASVDHPHVCRLLGICLTSA-VQLVTQLMPYGCLLDYVRQHQERICGQWLLNWCVQI 819 Query: 517 VKGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLT-VIRLDRQSLLHGGPKGTPLWM 693 KGM Y+ +LVH DL NVLL KI DFGL+ ++ D + G K WM Sbjct: 820 AKGMNYLEERHLVHRDLAARNVLLKNPNHVKITDFGLSKLLTADEKEYQADGGKVPIKWM 879 Query: 694 APEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTN 873 A E +L + ++D++S+G+ +W+L+T I +V N R P P Sbjct: 880 ALESILQWTYTHQSDVWSYGVTVWELMT-FGSKPYDGIPAKEIASVLENGERLPQPPICT 938 Query: 874 QKLSYLIHRCWHPQPALRPSFTEIDNAYLQ 963 ++ +I +CW P+ RP F E+ + Q Sbjct: 939 IEVYMIILKCWMIDPSSRPRFRELVGEFSQ 968
>Q8RY67:WAKLO_ARATH Wall-associated receptor kinase-like 14 precursor - Arabidopsis| thaliana (Mouse-ear cress) Length = 708 Score = 100 bits (250), Expect = 2e-20 Identities = 60/206 (29%), Positives = 110/206 (53%), Gaps = 10/206 (4%) Frame = +1 Query: 190 EELSKDKDGED------IGRFGKVFKGRCFGLEVAVKIPKVQELSPEQLEKFKQEVAINS 351 +E+ K DG IG +G V++G+ E V I +++ E L++ E+ + S Sbjct: 339 KEIEKATDGFSEKQKLGIGAYGTVYRGKLQNDEW-VAIKRLRHRDSESLDQVMNEIKLLS 397 Query: 352 EINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXS-NKARPLSLARRMRIARDIVKGM 528 ++HPN+VR LG C++ + LV E ++ L R+ +A K + Sbjct: 398 SVSHPNLVRLLGCCIEQGDPVLVYEYMPNGTLSEHLQRDRGSGLPWTLRLTVATQTAKAI 457 Query: 529 IYIHAAN---LVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWMAP 699 Y+H++ + H D+K N+LLD++ +K+ADFGL+ + + S + P+GTP ++ P Sbjct: 458 AYLHSSMNPPIYHRDIKSTNILLDYDFNSKVADFGLSRLGMTESSHISTAPQGTPGYLDP 517 Query: 700 EMLLGKPFDEKADIYSFGIILWQLLT 777 + +K+D+YSFG++L +++T Sbjct: 518 QYHQCFHLSDKSDVYSFGVVLAEIIT 543
>Q04912:RON_HUMAN Macrophage-stimulating protein receptor precursor - Homo sapiens| (Human) Length = 1400 Score = 100 bits (250), Expect = 2e-20 Identities = 78/269 (28%), Positives = 123/269 (45%), Gaps = 11/269 (4%) Frame = +1 Query: 163 IPAEQLIIEEELSKDKDGEDIGRFGKVFKGRCFG-----LEVAVK-IPKVQELSPEQLEK 324 IP E+++ + K G FG V+ G ++ A+K + ++ E+ +Q+E Sbjct: 1075 IPHERVVTHSDRVIGK-----GHFGVVYHGEYIDQAQNRIQCAIKSLSRITEM--QQVEA 1127 Query: 325 FKQEVAINSEINHPNVVRFLGACLKP--LNFRLVTEXXXXXXXXXXXSNKARPLSLARRM 498 F +E + +NHPNV+ +G L P L L+ S + P ++ + Sbjct: 1128 FLREGLLMRGLNHPNVLALIGIMLPPEGLPHVLLPYMCHGDLLQFIRSPQRNP-TVKDLI 1186 Query: 499 RIARDIVKGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSL---LHGG 669 + +GM Y+ VH DL N +LD + T K+ADFGL LDR+ H Sbjct: 1187 SFGLQVARGMEYLAEQKFVHRDLAARNCMLDESFTVKVADFGLARDILDREYYSVQQHRH 1246 Query: 670 PKGTPLWMAPEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYR 849 + WMA E L F K+D++SFG++LW+LLTR +A R Sbjct: 1247 ARLPVKWMALESLQTYRFTTKSDVWSFGVLLWELLTRGAPPYRHIDPFDLTHFLA-QGRR 1305 Query: 850 PPMPQGTNQKLSYLIHRCWHPQPALRPSF 936 P P+ L ++ +CW PA+RP+F Sbjct: 1306 LPQPEYCPDSLYQVMQQCWEADPAVRPTF 1334
>P29320:EPHA3_HUMAN Ephrin type-A receptor 3 precursor - Homo sapiens (Human)| Length = 983 Score = 100 bits (250), Expect = 2e-20 Identities = 74/266 (27%), Positives = 116/266 (43%), Gaps = 15/266 (5%) Frame = +1 Query: 193 ELSKDKDGEDI--------GRFGKVFKGRCF-----GLEVAVKIPKVQELSPEQLEKFKQ 333 E +K+ D +I G FG+V GR + VA+K KV + +Q F Sbjct: 611 EFAKELDATNISIDKVVGAGEFGEVCSGRLKLPSKKEISVAIKTLKVG-YTEKQRRDFLG 669 Query: 334 EVAINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARD 513 E +I + +HPN++R G K +VTE ++ + + + R Sbjct: 670 EASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLRKHDAQFTVIQLVGMLRG 729 Query: 514 IVKGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLH--GGPKGTPL 687 I GM Y+ VH DL N+L++ N K++DFGL+ + D + G K Sbjct: 730 IASGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIR 789 Query: 688 WMAPEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQG 867 W +PE + + F +D++S+GI+LW++++ IKAV YR P P Sbjct: 790 WTSPEAIAYRKFTSASDVWSYGIVLWEVMSYGERPYWEMSNQDVIKAVD-EGYRLPPPMD 848 Query: 868 TNQKLSYLIHRCWHPQPALRPSFTEI 945 L L+ CW RP F +I Sbjct: 849 CPAALYQLMLDCWQKDRNNRPKFEQI 874
>P41240:CSK_HUMAN Tyrosine-protein kinase CSK - Homo sapiens (Human)| Length = 450 Score = 100 bits (250), Expect = 2e-20 Identities = 70/242 (28%), Positives = 110/242 (45%), Gaps = 2/242 (0%) Frame = +1 Query: 226 GRFGKVFKGRCFGLEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGACLKPL 405 G FG V G G +VAVK K + + F E ++ +++ H N+V+ LG ++ Sbjct: 204 GEFGDVMLGDYRGNKVAVKCIK----NDATAQAFLAEASVMTQLRHSNLVQLLGVIVEEK 259 Query: 406 N-FRLVTEXXXXXXXXXXXSNKARP-LSLARRMRIARDIVKGMIYIHAANLVHLDLKPEN 579 +VTE ++ R L ++ + D+ + M Y+ N VH DL N Sbjct: 260 GGLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLEGNNFVHRDLAARN 319 Query: 580 VLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWMAPEMLLGKPFDEKADIYSFGII 759 VL+ + AK++DFGLT S K W APE L K F K+D++SFGI+ Sbjct: 320 VLVSEDNVAKVSDFGLT----KEASSTQDTGKLPVKWTAPEALREKKFSTKSDVWSFGIL 375 Query: 760 LWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPALRPSFT 939 LW++ + + V Y+ P G + ++ CWH A+RPSF Sbjct: 376 LWEIYSFGRVPYPRIPLKDVVPRVE-KGYKMDAPDGCPPAVYEVMKNCWHLDAAMRPSFL 434 Query: 940 EI 945 ++ Sbjct: 435 QL 436 Score = 35.0 bits (79), Expect = 1.1 Identities = 20/57 (35%), Positives = 30/57 (52%) Frame = +1 Query: 1417 PWFYGDLDKDAAFELLRNKQPGTFLVRFSSNPEHVGFVISVVDHKNTVVHIRVKHNA 1587 PWF+G + ++ A LL + G FLVR S+N + G V V H R+ ++A Sbjct: 81 PWFHGKITREQAERLLYPPETGLFLVRESTN--YPGDYTLCVSCDGKVEHYRIMYHA 135
>Q8VCT9:TESK2_MOUSE Dual specificity testis-specific protein kinase 2 - Mus musculus| (Mouse) Length = 570 Score = 100 bits (249), Expect = 2e-20 Identities = 83/280 (29%), Positives = 134/280 (47%), Gaps = 11/280 (3%) Frame = +1 Query: 190 EELSKDKDGEDIGRFGKVFK--GRCFGLEVAVKIPKVQELSPEQLEKFKQEVAINSEINH 363 ++ +++K G G F +VFK R G +A+K+ LS + K E+ + + ++H Sbjct: 57 DDFTREKIGS--GFFSEVFKVRHRASGQVMALKM---NTLSSNRANLLK-EMQLMNRLSH 110 Query: 364 PNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHA 543 PN++RF+G C+ +TE + L R+++A DI G+ Y+H Sbjct: 111 PNILRFMGVCVHQGQLHALTEYINSGNLEQLLDSDLY-LPWTVRVKLAYDIAVGLSYLHF 169 Query: 544 ANLVHLDLKPENVLL--DFNG-TAKIADFGLTV----IRLDRQSLLHGGPKGTPLWMAPE 702 + H DL +N L+ D NG +A +ADFGL + R+ L G+P WMAPE Sbjct: 170 KGIFHRDLTSKNCLIKRDENGYSAVVADFGLAEKIPDASIGREKL---AVVGSPFWMAPE 226 Query: 703 MLLGKPFDEKADIYSFGIILWQLLTR--XXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQ 876 +L +P++EKAD++S+GIIL +++ R + A N P Q Sbjct: 227 VLRDEPYNEKADVFSYGIILCEIIARIQADPDYLPRTENFGLDYDAFQNMVGDCPSDFLQ 286 Query: 877 KLSYLIHRCWHPQPALRPSFTEIDNAYLQPIIVETAIPDE 996 L C + P LRPSF EI + + + +P+E Sbjct: 287 ----LTFNCCNMDPKLRPSFEEIGKTLKE---IMSRLPEE 319
>P32593:MOS_MSVMT Serine/threonine-protein kinase-transforming protein mos - Moloney| murine sarcoma virus (strain ts110) Length = 354 Score = 100 bits (249), Expect = 2e-20 Identities = 81/261 (31%), Positives = 119/261 (45%), Gaps = 25/261 (9%) Frame = +1 Query: 226 GRFGKVFKGRCFGLEVAVK-IPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGACLKP 402 G FG V+K G+ VA+K + K E F E+ I + + H N+VR + A + Sbjct: 83 GGFGSVYKATYHGVPVAIKQVNKCTEDLRASQRSFWAELNI-AGLRHDNIVRVVAASTRT 141 Query: 403 LN-----FRLVTEXXXXXXXXXXXSNKAR---------PLSLARRMRIARDIVKGMIYIH 540 ++ E + R LSL + ++ + D+V G++++H Sbjct: 142 PEDSNSLGTIIMEFGGNVTLHQVIYDATRSPEPLSCRKQLSLGKCLKYSLDVVNGLLFLH 201 Query: 541 AANLVHLDLKPENVLLDFNGTAKIADFG----LTVIRLDRQSLLHGGPKGTPLWMAPEML 708 + +++HLDLKP N+L+ KI+DFG L V+R + S H G GT APE+L Sbjct: 202 SQSILHLDLKPANILISEQDVCKISDFGCSQKLQVLRGRQASPPHIG--GTYTHQAPEIL 259 Query: 709 LGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQG------T 870 G+ KADIYSFGI LWQ+ TR AV N RP + T Sbjct: 260 KGEIATPKADIYSFGITLWQMTTREVPYSGEPQYVQY--AVVAYNLRPSLAGAVFTASLT 317 Query: 871 NQKLSYLIHRCWHPQPALRPS 933 + L +I CW + RPS Sbjct: 318 GKALQNIIQSCWEARGLQRPS 338
>Q62689:JAK2_RAT Tyrosine-protein kinase JAK2 - Rattus norvegicus (Rat)| Length = 1132 Score = 100 bits (249), Expect = 2e-20 Identities = 76/291 (26%), Positives = 120/291 (41%), Gaps = 22/291 (7%) Frame = +1 Query: 139 AKGFVGLEIPAEQLIIEEELSKDKDGEDIGRFGKVFKGRCFGLE----VAVKIPKVQELS 306 A GF G + EE K G FG V R L+ V + K+Q + Sbjct: 829 ALGFSGAFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHST 888 Query: 307 PEQLEKFKQEVAINSEINHPNVVRFLGACLKP--LNFRLVTEXXXXXXXXXXXSNKARPL 480 E L F++E+ I + H N+V++ G C N RL+ E + Sbjct: 889 EEHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYLQKHKERI 948 Query: 481 SLARRMRIARDIVKGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLT-VIRLDRQSL 657 + ++ I KGM Y+ +H DL N+L++ KI DFGLT V+ D++ Sbjct: 949 DHKKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYY 1008 Query: 658 LHGGPKGTPL-WMAPEMLLGKPFDEKADIYSFGIILWQLLT--------------RXXXX 792 P +P+ W APE L F +D++SFG++L++L T Sbjct: 1009 KVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPVEFMRMIGND 1068 Query: 793 XXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPALRPSFTEI 945 + + NN R P P+G ++ ++ CW+ RPSF ++ Sbjct: 1069 KQGQMIVFHLIELLKNNGRLPRPEGCPDEIYVIMTECWNNNVNQRPSFRDL 1119 Score = 54.7 bits (130), Expect = 1e-06 Identities = 60/280 (21%), Positives = 118/280 (42%), Gaps = 18/280 (6%) Frame = +1 Query: 160 EIPAEQLIIEEELSKDKDGEDIGRFGKVFKG---------RCFGLEVAVKIPKVQELSPE 312 +I E LI E L + G F K+FKG + EV +K+ + + Sbjct: 539 KIRNEDLIFNESLGQ-------GTFTKIFKGVRREVGDYGQLHETEVLLKV--LDKAHRN 589 Query: 313 QLEKFKQEVAINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLAR 492 E F + ++ S+++H ++V G C+ LV E +++ Sbjct: 590 YSESFFEAASMMSQLSHKHLVLNYGVCVCGEENILVQEFVKFGSLDTYLKKNKNSINILW 649 Query: 493 RMRIARDIVKGMIYIHAANLVHLDLKPENVLL---DFNGTA-----KIADFGLTVIRLDR 648 ++ +A+ + M ++ +L+H ++ +N+LL + T K++D G+++ L + Sbjct: 650 KLGVAKQLAWAMHFLEEKSLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPK 709 Query: 649 QSLLHGGPKGTPLWMAPEMLLG-KPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIK 825 L P W+ PE + K D +SFG LW++ + ++ Sbjct: 710 DILQERIP-----WVPPECIENPKNLTLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQ 764 Query: 826 AVAINNYRPPMPQGTNQKLSYLIHRCWHPQPALRPSFTEI 945 + ++ P P+ T +L+ LI+ C +P RP+F + Sbjct: 765 FYE-DKHQLPAPKWT--ELANLINTCMDYEPDFRPAFRAV 801
>P08631:HCK_HUMAN Tyrosine-protein kinase HCK - Homo sapiens (Human)| Length = 526 Score = 100 bits (249), Expect = 2e-20 Identities = 73/265 (27%), Positives = 120/265 (45%), Gaps = 1/265 (0%) Frame = +1 Query: 160 EIPAEQLIIEEELSKDKDGEDIGRFGKVFKGRCFG-LEVAVKIPKVQELSPEQLEKFKQE 336 EIP E L +E++L G+FG+V+ +VAVK K +S +E F E Sbjct: 256 EIPRESLKLEKKLGA-------GQFGEVWMATYNKHTKVAVKTMKPGSMS---VEAFLAE 305 Query: 337 VAINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDI 516 + + H +V+ K + + S++ L + + + I Sbjct: 306 ANVMKTLQHDKLVKLHAVVTKEPIYIITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQI 365 Query: 517 VKGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWMA 696 +GM +I N +H DL+ N+L+ + KIADFGL + D + G K W A Sbjct: 366 AEGMAFIEQRNYIHRDLRAANILVSASLVCKIADFGLARVIEDNEYTAREGAKFPIKWTA 425 Query: 697 PEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQ 876 PE + F K+D++SFGI+L +++T I+A+ YR P P+ + Sbjct: 426 PEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRALE-RGYRMPRPENCPE 484 Query: 877 KLSYLIHRCWHPQPALRPSFTEIDN 951 +L ++ RCW +P RP+F I + Sbjct: 485 ELYNIMMRCWKNRPEERPTFEYIQS 509
>Q9UM73:ALK_HUMAN ALK tyrosine kinase receptor precursor - Homo sapiens (Human)| Length = 1620 Score = 100 bits (249), Expect = 2e-20 Identities = 82/281 (29%), Positives = 124/281 (44%), Gaps = 22/281 (7%) Frame = +1 Query: 226 GRFGKVFKGRCFG-------LEVAVKIPKVQELSPEQLE-KFKQEVAINSEINHPNVVRF 381 G FG+V++G+ G L+VAVK + E+ EQ E F E I S+ NH N+VR Sbjct: 1125 GAFGEVYEGQVSGMPNDPSPLQVAVKT--LPEVCSEQDELDFLMEALIISKFNHQNIVRC 1182 Query: 382 LGACLKPL-NFRLVTEXXXXXXXXXXXSNKARP-----LSLARRMRIARDIVKGMIYIHA 543 +G L+ L F L+ + RP L++ + +ARDI G Y+ Sbjct: 1183 IGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLAMLDLLHVARDIACGCQYLEE 1242 Query: 544 ANLVHLDLKPENVLLDFNG---TAKIADFGLTVIRLDRQSLLHGGPKGTPL-WMAPEMLL 711 + +H D+ N LL G AKI DFG+ GG P+ WM PE + Sbjct: 1243 NHFIHRDIAARNCLLTCPGPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFM 1302 Query: 712 GKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYL 891 F K D +SFG++LW++ + ++ V P P+ + + Sbjct: 1303 EGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDP-PKNCPGPVYRI 1361 Query: 892 IHRCWHPQPALRPSFT----EIDNAYLQPIIVETAIPDEVG 1002 + +CW QP RP+F I+ P ++ TA+P E G Sbjct: 1362 MTQCWQHQPEDRPNFAIILERIEYCTQDPDVINTALPIEYG 1402
>Q07292:KRAF1_CAEEL Raf homolog serine/threonine-protein kinase - Caenorhabditis elegans| Length = 813 Score = 100 bits (248), Expect = 3e-20 Identities = 63/195 (32%), Positives = 104/195 (53%), Gaps = 11/195 (5%) Frame = +1 Query: 226 GRFGKVFKGRCFGLEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGACLKPL 405 G FG V++G FG VA+K V + +P Q+ FK EVA+ + H NV+ F+G +P Sbjct: 490 GSFGTVYRGEFFGT-VAIKKLNVVDPTPSQMAAFKNEVAVLKKTRHLNVLLFMGWVREP- 547 Query: 406 NFRLVTE--XXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDLKPEN 579 ++T+ + + I + + GM Y+H+ N++H DLK N Sbjct: 548 EIAIITQWCEGSSLYRHIHVQEPRVEFEMGAIIDILKQVSLGMNYLHSKNIIHRDLKTNN 607 Query: 580 V-LLDFNGTAKIADFGLTVIRLDRQSLLHGG-----PKGTPLWMAPEMLL---GKPFDEK 732 + L+D T KI DFGL ++ + ++GG P G+ LWMAPE++ P+ + Sbjct: 608 IFLMDDMSTVKIGDFGLATVK--TKWTVNGGQQQQQPTGSILWMAPEVIRMQDDNPYTPQ 665 Query: 733 ADIYSFGIILWQLLT 777 +D+YSFGI ++++L+ Sbjct: 666 SDVYSFGICMYEILS 680
>Q60629:EPHA5_MOUSE Ephrin type-A receptor 5 precursor - Mus musculus (Mouse)| Length = 877 Score = 100 bits (248), Expect = 3e-20 Identities = 72/250 (28%), Positives = 109/250 (43%), Gaps = 8/250 (3%) Frame = +1 Query: 226 GRFGKVFKGRCFGLE------VAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLG 387 G FG+V G C L VA+K KV + +Q F E +I + +HPN++ G Sbjct: 523 GEFGEVCSG-CLKLPGKRELPVAIKTLKVG-YTEKQRRDFLGEASIMGQFDHPNIIHLEG 580 Query: 388 ACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDL 567 K +VTE ++ + + + R I GM Y+ VH DL Sbjct: 581 VVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGIAAGMKYLSDMGYVHRDL 640 Query: 568 KPENVLLDFNGTAKIADFGLTVIRLDRQSLLH--GGPKGTPLWMAPEMLLGKPFDEKADI 741 N+L++ N K++DFGL+ + D + G K W APE + + F +D+ Sbjct: 641 AARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDV 700 Query: 742 YSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPA 921 +S+GI++W++++ IKAV YR P P L L+ CW Sbjct: 701 WSYGIVMWEVVSYGERPYWEMTNQDVIKAVE-EGYRLPSPMDCPAALYQLMLDCWQKDRN 759 Query: 922 LRPSFTEIDN 951 RP F EI N Sbjct: 760 SRPKFDEIVN 769
>P54755:EPHA5_CHICK Ephrin type-A receptor 5 precursor - Gallus gallus (Chicken)| Length = 1013 Score = 100 bits (248), Expect = 3e-20 Identities = 70/247 (28%), Positives = 107/247 (43%), Gaps = 7/247 (2%) Frame = +1 Query: 226 GRFGKVFKGRCF-----GLEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGA 390 G FG+V GR VA+K KV + +Q F E +I + +HPN++ G Sbjct: 660 GEFGEVCSGRLKLQGKREFPVAIKTLKVG-YTEKQRRDFLGEASIMGQFDHPNIIHLEGV 718 Query: 391 CLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDLK 570 K +VTE ++ + + + R I GM Y+ VH DL Sbjct: 719 VTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGIASGMKYLSDMGYVHRDLA 778 Query: 571 PENVLLDFNGTAKIADFGLTVIRLDRQSLLH--GGPKGTPLWMAPEMLLGKPFDEKADIY 744 N+L++ N K++DFGL+ + D + G K W APE + + F +D++ Sbjct: 779 ARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDVW 838 Query: 745 SFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPAL 924 S+GI++W++++ IKAV YR P P L L+ CW Sbjct: 839 SYGIVMWEVMSYGERPYWEMTNQDVIKAVE-EGYRLPSPMDCPAALYQLMLDCWQKDRNS 897 Query: 925 RPSFTEI 945 RP F EI Sbjct: 898 RPKFDEI 904
>Q0VBZ0:CSK_BOVIN Tyrosine-protein kinase CSK - Bos taurus (Bovine)| Length = 450 Score = 100 bits (248), Expect = 3e-20 Identities = 70/242 (28%), Positives = 110/242 (45%), Gaps = 2/242 (0%) Frame = +1 Query: 226 GRFGKVFKGRCFGLEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGACLKPL 405 G FG V G G +VAVK K + + F E ++ +++ H N+V+ LG ++ Sbjct: 204 GEFGDVMLGDYRGNKVAVKCIK----NDATAQAFLAEASVMTQLRHSNLVQLLGVIVEEK 259 Query: 406 N-FRLVTEXXXXXXXXXXXSNKARP-LSLARRMRIARDIVKGMIYIHAANLVHLDLKPEN 579 + +VTE ++ R L ++ + D+ + M Y+ N VH DL N Sbjct: 260 SGLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLEGNNFVHRDLAARN 319 Query: 580 VLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWMAPEMLLGKPFDEKADIYSFGII 759 VL+ + AK++DFGLT S K W APE L K F K+D++SFGI+ Sbjct: 320 VLVSEDNVAKVSDFGLT----KEASSTQDTGKLPVKWTAPEALREKKFSTKSDVWSFGIL 375 Query: 760 LWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPALRPSFT 939 LW++ + + V Y+ P G + ++ CWH A RPSF Sbjct: 376 LWEIYSFGRVPYPRIPLKDVVPRVE-KGYKMDAPDGCPPAVYEVMKNCWHLDAATRPSFL 434 Query: 940 EI 945 ++ Sbjct: 435 QL 436 Score = 34.7 bits (78), Expect = 1.4 Identities = 20/57 (35%), Positives = 30/57 (52%) Frame = +1 Query: 1417 PWFYGDLDKDAAFELLRNKQPGTFLVRFSSNPEHVGFVISVVDHKNTVVHIRVKHNA 1587 PWF+G + ++ A LL + G FLVR S+N + G V V H R+ ++A Sbjct: 81 PWFHGKITREQAERLLCPPETGLFLVRESTN--YPGDYTLCVSCDGKVEHYRIMYHA 135
>Q9P289:MST4_HUMAN Serine/threonine-protein kinase MST4 - Homo sapiens (Human)| Length = 416 Score = 99.8 bits (247), Expect = 3e-20 Identities = 79/274 (28%), Positives = 131/274 (47%), Gaps = 9/274 (3%) Frame = +1 Query: 151 VGLEIPAEQLIIE--EELSKDKDGEDIGRFGKVFKGRCFGLE--VAVKIPKVQELSPEQL 318 V +++P Q I EEL + G FG+VFKG + VA+KI ++E + +++ Sbjct: 6 VAVQVPGMQNNIADPEELFTKLERIGKGSFGEVFKGIDNRTQQVVAIKIIDLEE-AEDEI 64 Query: 319 EKFKQEVAINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRM 498 E +QE+ + S+ + V ++ G+ LK ++ E +A P + Sbjct: 65 EDIQQEITVLSQCDSSYVTKYYGSYLKGSKLWIIMEYLGGGSALDLL--RAGPFDEFQIA 122 Query: 499 RIARDIVKGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFG----LTVIRLDRQSLLHG 666 + ++I+KG+ Y+H+ +H D+K NVLL G K+ADFG LT ++ R + + Sbjct: 123 TMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFV-- 180 Query: 667 GPKGTPLWMAPEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNY 846 GTP WMAPE++ +D KADI+S GI + L + + + NN Sbjct: 181 ---GTPFWMAPEVIQQSAYDSKADIWSLGITAIE-LAKGEPPNSDMHPMRVLFLIPKNN- 235 Query: 847 RPPMPQGT-NQKLSYLIHRCWHPQPALRPSFTEI 945 PP G + I C + P+ RP+ E+ Sbjct: 236 -PPTLVGDFTKSFKEFIDACLNKDPSFRPTAKEL 268
>P06240:LCK_MOUSE Proto-oncogene tyrosine-protein kinase LCK - Mus musculus (Mouse)| Length = 509 Score = 99.8 bits (247), Expect = 3e-20 Identities = 72/260 (27%), Positives = 118/260 (45%), Gaps = 1/260 (0%) Frame = +1 Query: 160 EIPAEQLIIEEELSKDKDGEDIGRFGKVFKGRCFG-LEVAVKIPKVQELSPEQLEKFKQE 336 E+P E L + E L G+FG+V+ G G +VAVK K +SP+ F E Sbjct: 239 EVPRETLKLVERLGA-------GQFGEVWMGYYNGHTKVAVKSLKQGSMSPDA---FLAE 288 Query: 337 VAINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDI 516 + ++ HP +VR + + + + L++ + + +A I Sbjct: 289 ANLMKQLQHPRLVRLYAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLNVNKLLDMAAQI 348 Query: 517 VKGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWMA 696 +GM +I N +H DL+ N+L+ + KIADFGL + D + G K W A Sbjct: 349 AEGMAFIEEQNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTA 408 Query: 697 PEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQ 876 PE + F K+D++SFGI+L +++T I+ + YR P + Sbjct: 409 PEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLE-RGYRMVRPDNCPE 467 Query: 877 KLSYLIHRCWHPQPALRPSF 936 +L +L+ CW +P RP+F Sbjct: 468 ELYHLMMLCWKERPEDRPTF 487
>P15208:INSR_MOUSE Insulin receptor precursor - Mus musculus (Mouse)| Length = 1372 Score = 99.8 bits (247), Expect = 3e-20 Identities = 78/281 (27%), Positives = 122/281 (43%), Gaps = 17/281 (6%) Frame = +1 Query: 160 EIPAEQLIIEEELSKDKDGEDIGRFGKVFKGRCFGL-------EVAVKIPKVQELSPEQL 318 E+P E++ + EL + G FG V++G + VAVK E++ Sbjct: 1007 EVPREKITLLRELGQ-------GSFGMVYEGNAKDIIKGEAETRVAVKTVNESASLRERI 1059 Query: 319 EKFKQEVAINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXX--------SNKAR 474 E F E ++ +VVR LG K +V E +N R Sbjct: 1060 E-FLNEASVMKGFTCHHVVRLLGVVSKGQPMLVVMELMAHGDLKSHLRSLRPDAENNPGR 1118 Query: 475 PL-SLARRMRIARDIVKGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQ 651 P +L +++ +I GM Y++A VH DL N ++ + T KI DFG+T + Sbjct: 1119 PPPTLQEMIQMTAEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETD 1178 Query: 652 SLLHGGPKGTPL-WMAPEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKA 828 GG P+ WM+PE L F +D++SFG++LW++ + +K Sbjct: 1179 YYRKGGKGLLPVRWMSPESLKDGVFTASSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKF 1238 Query: 829 VAINNYRPPMPQGTNQKLSYLIHRCWHPQPALRPSFTEIDN 951 V Y P P ++L+ L+ CW P +RP+F EI N Sbjct: 1239 VMDGGYLDP-PDNCPERLTDLMRMCWQFNPKMRPTFLEIVN 1278
>O73798:IGF1R_XENLA Insulin-like growth factor 1 receptor precursor - Xenopus laevis| (African clawed frog) Length = 1358 Score = 99.8 bits (247), Expect = 3e-20 Identities = 81/279 (29%), Positives = 124/279 (44%), Gaps = 17/279 (6%) Frame = +1 Query: 160 EIPAEQLIIEEELSKDKDGEDIGRFGKVFKGRCFGL-----EVAVKIPKVQELSP--EQL 318 E+P E++ + EL + G FG V++G G+ E V I V E + E++ Sbjct: 989 EVPREKITMNRELGQ-------GSFGMVYEGIAKGVVKDEAETKVAIKTVNEAASMRERI 1041 Query: 319 EKFKQEVAINSEINHPNVVRFLGAC--------LKPLNFRLVTEXXXXXXXXXXXSNKAR 474 E F E ++ E N +VVR LG + L R + SN + Sbjct: 1042 E-FLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPDTESNSGQ 1100 Query: 475 PL-SLARRMRIARDIVKGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQ 651 P SL + +++A +I GM Y++A VH DL N ++ + T KI DFG+T + Sbjct: 1101 PTPSLKKMIQMAGEIADGMSYLNANKFVHRDLAARNCMVTEDFTVKIGDFGMTRDIYETD 1160 Query: 652 SLLHGGPKGTPL-WMAPEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKA 828 GG P+ WM+PE L F +D++SFG++LW++ T ++ Sbjct: 1161 YYRKGGKGLLPVRWMSPESLKDGVFTTNSDVWSFGVVLWEIATLAEQPYQGMSNEQVLRF 1220 Query: 829 VAINNYRPPMPQGTNQKLSYLIHRCWHPQPALRPSFTEI 945 V + P L L+ CW P +RPSF EI Sbjct: 1221 V-MEGGLLEKPDNCPDMLFELMRMCWQFNPKMRPSFLEI 1258
>P29319:EPHA3_MOUSE Ephrin type-A receptor 3 precursor - Mus musculus (Mouse)| Length = 983 Score = 99.8 bits (247), Expect = 3e-20 Identities = 74/266 (27%), Positives = 116/266 (43%), Gaps = 15/266 (5%) Frame = +1 Query: 193 ELSKDKDGEDI--------GRFGKVFKGRCF-----GLEVAVKIPKVQELSPEQLEKFKQ 333 E +K+ D +I G FG+V GR + VA+K KV + +Q F Sbjct: 611 EFAKELDATNISIDKVVGAGEFGEVCSGRLKLPSKKEISVAIKTLKVG-YTEKQRRDFLG 669 Query: 334 EVAINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARD 513 E +I + +HPN++R G K +VTE ++ + + + R Sbjct: 670 EASIMGQFDHPNIIRLEGVVTKSKPEMIVTEYMENGSLDSFLRKHDAQFTVIQLVGMLRG 729 Query: 514 IVKGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLH--GGPKGTPL 687 I GM Y+ VH DL N+L++ N K++DFGL+ + D + G K Sbjct: 730 IASGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIR 789 Query: 688 WMAPEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQG 867 W +PE + + F +D++S+GI+LW++++ IKAV YR P P Sbjct: 790 WTSPEAMSYRKFTSASDVWSYGIVLWEVMSYGERPYSQMSNQDVIKAVD-ERYRLPPPMD 848 Query: 868 TNQKLSYLIHRCWHPQPALRPSFTEI 945 L L+ CW RP F +I Sbjct: 849 CPAALYQLMLDCWQKDRNNRPKFEQI 874
>Q99JT2:MST4_MOUSE Serine/threonine-protein kinase MST4 - Mus musculus (Mouse)| Length = 416 Score = 99.4 bits (246), Expect = 5e-20 Identities = 79/274 (28%), Positives = 131/274 (47%), Gaps = 9/274 (3%) Frame = +1 Query: 151 VGLEIPAEQLIIE--EELSKDKDGEDIGRFGKVFKGRCFGLE--VAVKIPKVQELSPEQL 318 V +++P Q I EEL + G FG+VFKG + VA+KI ++E + +++ Sbjct: 6 VAVQVPGMQNNIADPEELFTKLERIGKGSFGEVFKGIDNRTQQVVAIKIIDLEE-AEDEI 64 Query: 319 EKFKQEVAINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRM 498 E +QE+ + S+ + V ++ G+ LK ++ E +A P + Sbjct: 65 EDIQQEITVLSQCDSSYVTKYYGSYLKGSKLWIIMEYLGGGSALDLL--RAGPFDEFQIA 122 Query: 499 RIARDIVKGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFG----LTVIRLDRQSLLHG 666 + ++I+KG+ Y+H+ +H D+K NVLL G K+ADFG LT ++ R + + Sbjct: 123 TMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFV-- 180 Query: 667 GPKGTPLWMAPEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNY 846 GTP WMAPE++ +D KADI+S GI + L + + + NN Sbjct: 181 ---GTPFWMAPEVIQQSAYDSKADIWSLGITAIE-LAKGEPPNSDMHPMRVLFLIPKNN- 235 Query: 847 RPPMPQGT-NQKLSYLIHRCWHPQPALRPSFTEI 945 PP G + I C + P+ RP+ E+ Sbjct: 236 -PPTLIGDFTKSFKEFIDACLNKDPSFRPTAKEL 268
>P00536:MOS_MOUSE Proto-oncogene serine/threonine-protein kinase mos - Mus musculus| (Mouse) Length = 390 Score = 99.4 bits (246), Expect = 5e-20 Identities = 79/260 (30%), Positives = 117/260 (45%), Gaps = 25/260 (9%) Frame = +1 Query: 226 GRFGKVFKGRCFGLEVAVK-IPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGACLKP 402 G FG V+K G+ VA+K + K + F E+ I + + H N+VR + A + Sbjct: 119 GGFGSVYKATYHGVPVAIKQVNKCTKDLRASQRSFWAELNI-ARLRHDNIVRVVAASTRT 177 Query: 403 LN-----FRLVTEXXXXXXXXXXXSNKAR---------PLSLARRMRIARDIVKGMIYIH 540 ++ E R LSL + ++ + D+V G++++H Sbjct: 178 PEDSNSLGTIIMEFGGNVTLHQVIYGATRSPEPLSCREQLSLGKCLKYSLDVVNGLLFLH 237 Query: 541 AANLVHLDLKPENVLLDFNGTAKIADFG----LTVIRLDRQSLLHGGPKGTPLWMAPEML 708 + +++HLDLKP N+L+ KI+DFG L V+R + S H G GT APE+L Sbjct: 238 SQSILHLDLKPANILISEQDVCKISDFGCSQKLQVLRCRQASPHHIG--GTYTHQAPEIL 295 Query: 709 LGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQG------T 870 G+ KADIYSFGI LWQ+ TR AV N RP + T Sbjct: 296 KGEIATPKADIYSFGITLWQMTTREVPYSGEPQYVQY--AVVAYNLRPSLAGAVFTASLT 353 Query: 871 NQKLSYLIHRCWHPQPALRP 930 + L +I CW + RP Sbjct: 354 GKTLQNIIQSCWEARALQRP 373
>P08923:LTK_MOUSE Leukocyte tyrosine kinase receptor precursor - Mus musculus (Mouse)| Length = 888 Score = 99.4 bits (246), Expect = 5e-20 Identities = 77/282 (27%), Positives = 123/282 (43%), Gaps = 20/282 (7%) Frame = +1 Query: 226 GRFGKVFKGRCFGLE-----VAVKIPKVQELSPEQLE-KFKQEVAINSEINHPNVVRFLG 387 G FG+V++G GL + V I + EL Q E F E I S+ +H N+VR +G Sbjct: 515 GAFGEVYEGLVTGLPGDSSPLPVAIKTLPELCSHQDELDFLMEALIISKFSHQNIVRCVG 574 Query: 388 ACLKPLNFRLVTEXXXXXXXXXXXSN------KARPLSLARRMRIARDIVKGMIYIHAAN 549 + ++ E + + PL++ +++A+DI +G Y+ + Sbjct: 575 LSFRSAPRLILLELMSGGDMKSFLRHSRPHPGQLAPLTMQDLLQLAQDIAQGCHYLEENH 634 Query: 550 LVHLDLKPENVLLDFNG---TAKIADFGLTVIRLDRQSLLHGGPKGTPL-WMAPEMLLGK 717 +H D+ N LL +G AKI DFG+ GG P+ WM PE LL Sbjct: 635 FIHRDIAARNCLLSCSGASRVAKIGDFGMARDIYQASYYRKGGRTLLPVKWMPPEALLEG 694 Query: 718 PFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIH 897 F K D +SFG++LW++ + + +A N P P+ + ++ Sbjct: 695 LFTSKTDSWSFGVLLWEIFSLGYMPYPGHTNQEVLDFIATGNRMDP-PRNCPGPVYRIMT 753 Query: 898 RCWHPQPALRPSF----TEIDNAYLQPIIVETAIPDEVGRVL 1011 +CW QP LRP F I P ++ + +P E G +L Sbjct: 754 QCWQHQPELRPDFGSILERIQYCTQDPDVLNSPLPMEPGPIL 795
>Q32L23:LIMK2_BOVIN LIM domain kinase 2 - Bos taurus (Bovine)| Length = 638 Score = 99.4 bits (246), Expect = 5e-20 Identities = 72/282 (25%), Positives = 125/282 (44%), Gaps = 23/282 (8%) Frame = +1 Query: 214 GEDIGR--FGKVFKGRCFGLEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLG 387 GE +G+ FG+ K + + ++ E + F EV + ++HPNV++F+G Sbjct: 334 GEVLGKGFFGQAIKVTHKATGKVMVMNELIRCDEETQKTFLTEVKVMRSLDHPNVLKFIG 393 Query: 388 ACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDL 567 K L+TE N P +++R A+ I GM Y+H+ ++H DL Sbjct: 394 VLYKDKKLNLLTEYIEGGTLKDFLRN-VDPFPWQQKVRFAKGIASGMAYLHSMCIIHRDL 452 Query: 568 KPENVLLDFNGTAKIADFGLTVIRLD-------------RQSLLHGGPK------GTPLW 690 N L+ + T +ADFGL+ + ++ +++L K G P W Sbjct: 453 NSHNCLIKLDKTVVVADFGLSRLIVEERKKPPVEKATTKKRTLRKSDRKKRYTVVGNPYW 512 Query: 691 MAPEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGT 870 MAPEML GK +DE D++SFGI+L +++ + + +P+ Sbjct: 513 MAPEMLNGKSYDETVDVFSFGIVLCEIIGQVYADPDCLPRTLDFGLNVKLFWEKFVPEEC 572 Query: 871 NQKLSYLIHRCWHPQPALRPSFTEIDNAY--LQPIIVETAIP 990 L C +P RP+F+++++ + L + E IP Sbjct: 573 PPAFFPLAAICCRLEPESRPAFSKLEDFFEALSLYLGELGIP 614
>Q62120:JAK2_MOUSE Tyrosine-protein kinase JAK2 - Mus musculus (Mouse)| Length = 1129 Score = 99.4 bits (246), Expect = 5e-20 Identities = 74/297 (24%), Positives = 124/297 (41%), Gaps = 22/297 (7%) Frame = +1 Query: 139 AKGFVGLEIPAEQLIIEEELSKDKDGEDIGRFGKVFKGRCFGLE----VAVKIPKVQELS 306 A GF G + EE K G FG V R L+ V + K+Q + Sbjct: 829 ALGFSGAFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHST 888 Query: 307 PEQLEKFKQEVAINSEINHPNVVRFLGACLKP--LNFRLVTEXXXXXXXXXXXSNKARPL 480 E L F++E+ I + H N+V++ G C N RL+ E + Sbjct: 889 EEHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYLQKHKERI 948 Query: 481 SLARRMRIARDIVKGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLT-VIRLDRQSL 657 + ++ I KGM Y+ +H DL N+L++ KI DFGLT V+ D++ Sbjct: 949 DHKKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYY 1008 Query: 658 LHGGPKGTPL-WMAPEMLLGKPFDEKADIYSFGIILWQLLT--------------RXXXX 792 P +P+ W AP+ L F +D++SFG++L++L T Sbjct: 1009 KVKEPGESPIFWYAPQSLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPVEFMRMIGND 1068 Query: 793 XXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPALRPSFTEIDNAYLQ 963 + + +N R P P+G ++ ++ CW+ + RPSF ++ +++ Sbjct: 1069 KQGQMIVFHLIELLKSNGRLPRPEGCPDEIYVIMTECWNNNVSQRPSFRDLSFGWIK 1125 Score = 55.8 bits (133), Expect = 6e-07 Identities = 60/280 (21%), Positives = 119/280 (42%), Gaps = 18/280 (6%) Frame = +1 Query: 160 EIPAEQLIIEEELSKDKDGEDIGRFGKVFKG---------RCFGLEVAVKIPKVQELSPE 312 +I E LI E L + G F K+FKG + EV +K+ + + Sbjct: 539 KIRNEDLIFNESLGQ-------GTFTKIFKGVRREVGDYGQLHKTEVLLKV--LDKAHRN 589 Query: 313 QLEKFKQEVAINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLAR 492 E F + ++ S+++H ++V G C+ LV E +++ Sbjct: 590 YSESFFEAASMMSQLSHKHLVLNYGVCVCGEENILVQEFVKFGSLDTYLKKNKNSINILW 649 Query: 493 RMRIARDIVKGMIYIHAANLVHLDLKPENVLL---DFNGTA-----KIADFGLTVIRLDR 648 ++ +A+ + M ++ +L+H ++ +N+LL + T K++D G+++ L + Sbjct: 650 KLGVAKQLAWAMHFLEEKSLIHGNVCAKNILLIREEDRRTGNPPFIKLSDPGISITVLPK 709 Query: 649 QSLLHGGPKGTPLWMAPEMLLG-KPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIK 825 L P W+ PE + K + D +SFG LW++ + ++ Sbjct: 710 DILQERIP-----WVPPECIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQ 764 Query: 826 AVAINNYRPPMPQGTNQKLSYLIHRCWHPQPALRPSFTEI 945 + ++ P P+ T +L+ LI+ C +P RP+F + Sbjct: 765 FYE-DKHQLPAPKWT--ELANLINNCMDYEPDFRPAFRAV 801
>P54754:EPHB3_MOUSE Ephrin type-B receptor 3 precursor - Mus musculus (Mouse)| Length = 993 Score = 99.4 bits (246), Expect = 5e-20 Identities = 72/251 (28%), Positives = 112/251 (44%), Gaps = 9/251 (3%) Frame = +1 Query: 226 GRFGKVFKGRCF-----GLEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGA 390 G FG+V +GR + VA+K KV + Q F E +I + +HPN++R G Sbjct: 637 GEFGEVCRGRLKLPGRREVFVAIKTLKVG-YTERQRRDFLSEASIMGQFDHPNIIRLEGV 695 Query: 391 CLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDLK 570 K ++TE ++ + + + R I GM Y+ N VH DL Sbjct: 696 VTKSRPVMILTEFMENCALDSFLRLNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLA 755 Query: 571 PENVLLDFNGTAKIADFGLTVIRLDRQS----LLHGGPKGTPLWMAPEMLLGKPFDEKAD 738 N+L++ N K++DFGL+ D S G K W APE + + F +D Sbjct: 756 ARNILVNSNLVCKVSDFGLSRFLEDDPSDPTYTSSLGGKIPIRWTAPEAIAYRKFTSASD 815 Query: 739 IYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQP 918 ++S+GI++W++++ I AV +YR P P L L+ CW Sbjct: 816 VWSYGIVMWEVMSYGERPYWDMSNQDVINAVE-QDYRLPPPMDCPTALHQLMLDCWVRDR 874 Query: 919 ALRPSFTEIDN 951 LRP F++I N Sbjct: 875 NLRPKFSQIVN 885
>P54753:EPHB3_HUMAN Ephrin type-B receptor 3 precursor - Homo sapiens (Human)| Length = 998 Score = 99.4 bits (246), Expect = 5e-20 Identities = 72/251 (28%), Positives = 112/251 (44%), Gaps = 9/251 (3%) Frame = +1 Query: 226 GRFGKVFKGRCFG-----LEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGA 390 G FG+V +GR + VA+K KV + Q F E +I + +HPN++R G Sbjct: 642 GEFGEVCRGRLKQPGRREVFVAIKTLKVG-YTERQRRDFLSEASIMGQFDHPNIIRLEGV 700 Query: 391 CLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDLK 570 K ++TE ++ + + + R I GM Y+ N VH DL Sbjct: 701 VTKSRPVMILTEFMENCALDSFLRLNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLA 760 Query: 571 PENVLLDFNGTAKIADFGLTVIRLDRQS----LLHGGPKGTPLWMAPEMLLGKPFDEKAD 738 N+L++ N K++DFGL+ D S G K W APE + + F +D Sbjct: 761 ARNILVNSNLVCKVSDFGLSRFLEDDPSDPTYTSSLGGKIPIRWTAPEAIAYRKFTSASD 820 Query: 739 IYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQP 918 ++S+GI++W++++ I AV +YR P P L L+ CW Sbjct: 821 VWSYGIVMWEVMSYGERPYWDMSNQDVINAVE-QDYRLPPPMDCPTALHQLMLDCWVRDR 879 Query: 919 ALRPSFTEIDN 951 LRP F++I N Sbjct: 880 NLRPKFSQIVN 890
>O13148:EPA4A_DANRE Ephrin type-A receptor 4a - Danio rerio (Zebrafish) (Brachydanio| rerio) Length = 292 Score = 99.4 bits (246), Expect = 5e-20 Identities = 70/258 (27%), Positives = 115/258 (44%), Gaps = 15/258 (5%) Frame = +1 Query: 223 IGRFGKVFKGRCF---GLEVAVKIPKVQE-LSPEQLEKFKQEVAINSEINHPNVVRFLGA 390 IG FG+V GR E+ V I ++ + +Q F E +I + +HPN++R G Sbjct: 3 IGEFGEVCSGRLKMPGKREICVAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNIIRLEGV 62 Query: 391 CLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDLK 570 K ++TE ++ + + I R I GM Y+ + VH DL Sbjct: 63 VTKCKPVMIITEYMENGSLDAFLRKNDGRFTVIQLVGILRGIASGMKYLSDMSYVHRDLA 122 Query: 571 PENVLLDFNGTAKIADFGLT-VIRLDRQSLL----------HGGPKGTPLWMAPEMLLGK 717 N+L++ N K++DFG++ V+ D + G K W APE + + Sbjct: 123 ARNILVNSNLVCKVSDFGMSRVLEEDPDAAYTTREITGTYQSQGGKIPIRWTAPEAITYR 182 Query: 718 PFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIH 897 F +D++S+GI++W++++ IKA+ YR P P L L+ Sbjct: 183 KFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIE-EGYRLPPPMDCPVSLHQLML 241 Query: 898 RCWHPQPALRPSFTEIDN 951 CW + A RP F++I N Sbjct: 242 DCWQKERAERPKFSQIVN 259
>Q924U5:TESK2_RAT Dual specificity testis-specific protein kinase 2 - Rattus| norvegicus (Rat) Length = 570 Score = 99.0 bits (245), Expect = 6e-20 Identities = 83/264 (31%), Positives = 132/264 (50%), Gaps = 12/264 (4%) Frame = +1 Query: 190 EELSKDKDGEDIGRFGKVFK--GRCFGLEVAVKIPKVQELSPEQLEKFKQEVAINSEINH 363 ++ +++K G G F +VFK R G +A+K+ LS + K E+ + + ++H Sbjct: 57 DDFTREKIGS--GFFSEVFKVRHRASGQVMALKM---NTLSSNRANLLK-EMQLMNRLSH 110 Query: 364 PNVVRFLGACLKPLNFRLVTEXXXXXXXXXXX-SNKARPLSLARRMRIARDIVKGMIYIH 540 PN++RF+G C+ +TE SN P ++ R+++A DI G+ Y+H Sbjct: 111 PNILRFMGVCVHQGQLHALTEYINSGNLEQLLDSNLYLPWTV--RVKLAYDIAVGLSYLH 168 Query: 541 AANLVHLDLKPENVLL--DFNG-TAKIADFGLTVIRLDRQSLLHGGPK----GTPLWMAP 699 + H DL +N L+ D NG +A +ADFGL ++ S+ G K G+P WMAP Sbjct: 169 FKGIFHRDLTSKNCLIKRDENGYSAVVADFGLAE-KIPDASI--GSEKLAVVGSPFWMAP 225 Query: 700 EMLLGKPFDEKADIYSFGIILWQLLTR--XXXXXXXXXXXXXIKAVAINNYRPPMPQGTN 873 E+L +P++EKAD++S+GIIL +++ R + A + P Sbjct: 226 EVLRDEPYNEKADVFSYGIILCEIIARIQADPDYLPRTENFGLDYDAFQHMVGDCPSDFL 285 Query: 874 QKLSYLIHRCWHPQPALRPSFTEI 945 Q L C + P LRPSF EI Sbjct: 286 Q----LTFNCCNMDPKLRPSFEEI 305
>Q62270:SRMS_MOUSE Tyrosine-protein kinase Srms - Mus musculus (Mouse)| Length = 496 Score = 99.0 bits (245), Expect = 6e-20 Identities = 72/261 (27%), Positives = 118/261 (45%), Gaps = 2/261 (0%) Frame = +1 Query: 160 EIPAEQLIIEEELSKDKDGEDIGRFGKVFKGRCFG-LEVAVKIPKVQELSPEQLEKFKQE 336 E P + ++ +L + G FG+V++G G + VAVK+ K ++ L K E Sbjct: 228 ERPRSEFVLRRKLGE-------GFFGEVWEGLWLGSIPVAVKVIKSADMKLADLTK---E 277 Query: 337 VAINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXX-SNKARPLSLARRMRIARD 513 + + H ++R C +VTE S++ + LSL + A Sbjct: 278 IEALKSLRHERLIRLHAICSLGEPVYIVTELMGKGNLQVYLGSSEGKALSLPHLLGFACQ 337 Query: 514 IVKGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWM 693 + +GM Y+ +VH DL NVL+ + T K+ADFGL + D G K W Sbjct: 338 VAEGMSYLEERRVVHRDLAARNVLVGDDLTCKVADFGLARLLKDDVYSPSSGSKIPVKWT 397 Query: 694 APEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTN 873 APE + F +K+D++SFGI+L+++ T ++ ++ YR P P Sbjct: 398 APEAANYRVFSQKSDVWSFGILLYEVFTYGQCPYEGMTNHETLQQIS-RGYRLPRPAVCP 456 Query: 874 QKLSYLIHRCWHPQPALRPSF 936 ++ L+ CW P RP+F Sbjct: 457 AEVYVLMVECWKGSPEERPTF 477
>Q3UFB7:NTRK1_MOUSE High affinity nerve growth factor receptor precursor - Mus musculus| (Mouse) Length = 799 Score = 99.0 bits (245), Expect = 6e-20 Identities = 77/321 (23%), Positives = 138/321 (42%), Gaps = 23/321 (7%) Frame = +1 Query: 76 AAMQPSAGPGTGAAIH---DPFGVAKGFVGLEIPAEQLIIEEELSKDKDGEDIGRFGKVF 246 +++ P+ G G+G H +P + V I + +I++ EL + G FGKVF Sbjct: 477 SSLSPTEGKGSGLQGHIMENPQYFSDTCVH-HIKRQDIILKWELGE-------GAFGKVF 528 Query: 247 KGRCFGL-----EVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGACLK---- 399 C+ L ++ V + ++E S + F++E + + + H ++VRF G C + Sbjct: 529 LAECYNLLNDQDKMLVAVKALKEASENARQDFQREAELLTMLQHQHIVRFFGVCTEGGPL 588 Query: 400 ----------PLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAAN 549 LN L + PL L + + +A + GM+Y+ + + Sbjct: 589 LMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLASLH 648 Query: 550 LVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPL-WMAPEMLLGKPFD 726 VH DL N L+ KI DFG++ GG P+ WM PE +L + F Sbjct: 649 FVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFS 708 Query: 727 EKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCW 906 ++D++SFG++LW++ T I+ + P+ + ++ CW Sbjct: 709 TESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIECIT-QGRELERPRACPPDVYAIMRGCW 767 Query: 907 HPQPALRPSFTEIDNAYLQPI 969 +P R S ++ +A LQ + Sbjct: 768 QREPQQRLSMKDV-HARLQAL 787
>O54785:LIMK2_MOUSE LIM domain kinase 2 - Mus musculus (Mouse)| Length = 638 Score = 99.0 bits (245), Expect = 6e-20 Identities = 72/282 (25%), Positives = 126/282 (44%), Gaps = 23/282 (8%) Frame = +1 Query: 214 GEDIGR--FGKVFKGRCFGLEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLG 387 GE +G+ FG+ K + + ++ E + F EV + ++HPNV++F+G Sbjct: 334 GEVLGKGFFGQAIKVTHKATGKVMVMKELIRCDEETQKTFLTEVKVMRSLDHPNVLKFIG 393 Query: 388 ACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDL 567 K L+TE + P +++R A+ I GM Y+H+ ++H DL Sbjct: 394 VLYKDKKLNLLTEYIEGGTLKDFLRS-VDPFPWQQKVRFAKGISSGMAYLHSMCIIHRDL 452 Query: 568 KPENVLLDFNGTAKIADFGLTVIRLD-------------RQSLLHGGPK------GTPLW 690 N L+ + T +ADFGL+ + ++ +++L K G P W Sbjct: 453 NSHNCLIKLDKTVVVADFGLSRLIVEERKRPPVEKATTKKRTLRKSDRKKRYTVVGNPYW 512 Query: 691 MAPEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGT 870 MAPEML GK +DE D++SFGI+L +++ + + +P Sbjct: 513 MAPEMLNGKSYDETVDVFSFGIVLCEIIGQVYADPDCLPRTLDFGLNVKLFWEKFVPTDC 572 Query: 871 NQKLSYLIHRCWHPQPALRPSFTEIDNAY--LQPIIVETAIP 990 L C +P RP+F+++++++ L + E AIP Sbjct: 573 PPAFFPLAAICCKLEPESRPAFSKLEDSFEALSLFLGELAIP 614
>P53666:LIMK2_CHICK LIM domain kinase 2 - Gallus gallus (Chicken)| Length = 642 Score = 99.0 bits (245), Expect = 6e-20 Identities = 73/282 (25%), Positives = 125/282 (44%), Gaps = 23/282 (8%) Frame = +1 Query: 214 GEDIGR--FGKVFKGRCFGLEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLG 387 GE +G+ FG+ K + + ++ E + F EV + ++HPNV++F+G Sbjct: 334 GEVLGKGFFGQAIKVTHKATGKVMVMKELIRCDEETQKTFLTEVKVMRSLDHPNVLKFIG 393 Query: 388 ACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDL 567 K L+TE N A P +++ A+ I GM Y+H+ ++H DL Sbjct: 394 VLYKDKKLNLLTEYIEGGTLKDFLRN-ADPFPWQQKVSFAKGIASGMAYLHSMCIIHRDL 452 Query: 568 KPENVLLDFNGTAKIADFGLTVIRLD-------------RQSLLHGGPK------GTPLW 690 N L+ + T +ADFGL+ + ++ +++L K G P W Sbjct: 453 NSHNCLIKLDKTVVVADFGLSRLIVEERKKPTLEKPSAKKRTLRKSDRKKRYTVVGNPYW 512 Query: 691 MAPEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGT 870 MAPEML G+ +DE DI+SFGI+L +++ + + +P Sbjct: 513 MAPEMLNGQSYDETVDIFSFGIVLCEIIGQVYADPDCLPRTLDFGLNVKLFWEKFVPADC 572 Query: 871 NQKLSYLIHRCWHPQPALRPSFTEIDNAY--LQPIIVETAIP 990 L C +P RP F+++++++ L + E AIP Sbjct: 573 PPAFFPLAAICCRLEPESRPPFSKLEDSFEALSLYLGELAIP 614
>P15127:INSR_RAT Insulin receptor precursor - Rattus norvegicus (Rat)| Length = 1383 Score = 99.0 bits (245), Expect = 6e-20 Identities = 78/281 (27%), Positives = 122/281 (43%), Gaps = 17/281 (6%) Frame = +1 Query: 160 EIPAEQLIIEEELSKDKDGEDIGRFGKVFKGRCFGL-------EVAVKIPKVQELSPEQL 318 E+P E++ + EL + G FG V++G + VAVK E++ Sbjct: 1018 EVPREKITLLRELGQ-------GSFGMVYEGNAKDIIKGEVETRVAVKTVNESASLRERI 1070 Query: 319 EKFKQEVAINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXX--------SNKAR 474 E F E ++ +VVR LG K +V E +N R Sbjct: 1071 E-FLNEASVMKGFTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSHLRSLRPDAENNPGR 1129 Query: 475 PL-SLARRMRIARDIVKGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQ 651 P +L +++ +I GM Y++A VH DL N ++ + T KI DFG+T + Sbjct: 1130 PPPTLQEMIQMTAEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETD 1189 Query: 652 SLLHGGPKGTPL-WMAPEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKA 828 GG P+ WM+PE L F +D++SFG++LW++ + +K Sbjct: 1190 YYRKGGKGLLPVRWMSPESLKDGVFTASSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKF 1249 Query: 829 VAINNYRPPMPQGTNQKLSYLIHRCWHPQPALRPSFTEIDN 951 V Y P P ++L+ L+ CW P +RP+F EI N Sbjct: 1250 VMDGGYLDP-PDNCPERLTDLMRMCWQFNPKMRPTFLEIVN 1289
>P29318:EPHA3_CHICK Ephrin type-A receptor 3 precursor - Gallus gallus (Chicken)| Length = 983 Score = 99.0 bits (245), Expect = 6e-20 Identities = 73/272 (26%), Positives = 115/272 (42%), Gaps = 21/272 (7%) Frame = +1 Query: 193 ELSKDKDGEDI--------GRFGKVFKGRCFGLEVAVKIPKVQELS-----------PEQ 315 E +K+ D +I G FG+V GR +K+P +E+S +Q Sbjct: 611 EFAKELDASNISIDKVVGAGEFGEVCSGR-------LKLPSKKEISVAIKTLKAGYTEKQ 663 Query: 316 LEKFKQEVAINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARR 495 F E +I + +HPN++R G K +VTE ++ + Sbjct: 664 RRDFLGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLRKHDAQFTVIQL 723 Query: 496 MRIARDIVKGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLH--GG 669 + + R I GM Y+ VH DL N+L++ N K++DFGL+ + D + G Sbjct: 724 VGMLRGIASGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRG 783 Query: 670 PKGTPLWMAPEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYR 849 K W +PE + + F +D +S+GI+LW++++ IKAV YR Sbjct: 784 GKIPIRWTSPEAIAYRKFTSASDAWSYGIVLWEVMSYGERPYWEMSFQDVIKAVD-EGYR 842 Query: 850 PPMPQGTNQKLSYLIHRCWHPQPALRPSFTEI 945 P P L L+ CW RP F +I Sbjct: 843 LPPPMDCPAALYQLMLDCWQKDRNNRPKFEQI 874
>O65472:CRK12_ARATH Putative cysteine-rich receptor-like protein kinase 12 precursor -| Arabidopsis thaliana (Mouse-ear cress) Length = 690 Score = 99.0 bits (245), Expect = 6e-20 Identities = 70/216 (32%), Positives = 113/216 (52%), Gaps = 7/216 (3%) Frame = +1 Query: 148 FVGLEIPAEQLIIEEELSKDKDGEDIGRFGKVFKGRCF-GLEVAVKIPKVQELSPEQLEK 324 F L+ ++ E +K G+ G FG+V+KG G EVAVK ++ + S + ++ Sbjct: 352 FQQLDFKTIEVATENFAKTNKLGQ--GGFGEVYKGTLVNGTEVAVK--RLSKTSEQGAQE 407 Query: 325 FKQEVAINSEINHPNVVRFLGACLKPLNFRLVTE--XXXXXXXXXXXSNKARPLSLARRM 498 FK EV + +++ H N+V+ LG CL+P LV E K L +R Sbjct: 408 FKNEVVLVAKLQHRNLVKLLGYCLEPEEKILVYEFVPNKSLDYFLFDPTKQGQLDWTKRY 467 Query: 499 RIARDIVKGMIYIH---AANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGG 669 I I +G++Y+H ++H DLK N+LLD + KIADFG+ I QS+ + Sbjct: 468 NIIGGITRGILYLHQDSRLTIIHRDLKASNILLDADMIPKIADFGMARISGIDQSVANTK 527 Query: 670 P-KGTPLWMAPEMLLGKPFDEKADIYSFGIILWQLL 774 GT +M PE ++ F K+D+YSFG+++ +++ Sbjct: 528 RIAGTFGYMPPEYVIHGQFSMKSDVYSFGVLILEII 563
>Q9LDI3:CPK24_ARATH CBL-interacting serine/threonine-protein kinase 24 - Arabidopsis| thaliana (Mouse-ear cress) Length = 446 Score = 99.0 bits (245), Expect = 6e-20 Identities = 75/238 (31%), Positives = 112/238 (47%), Gaps = 4/238 (1%) Frame = +1 Query: 226 GRFGKVFKGRCF--GLEVAVKI-PKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGACL 396 G F KV R G VA+KI K L +++ K+E++I + HPN+VR Sbjct: 20 GTFAKVKFARNTDTGDNVAIKIMAKSTILKNRMVDQIKREISIMKIVRHPNIVRLYEVLA 79 Query: 397 KPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDLKPE 576 P +V E +K R L + + + +V + + H + H DLKPE Sbjct: 80 SPSKIYIVLEFVTGGELFDRIVHKGR-LEESESRKYFQQLVDAVAHCHCKGVYHRDLKPE 138 Query: 577 NVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWMAPEMLLGKPFD-EKADIYSFG 753 N+LLD NG K++DFGL+ + + LL GTP ++APE+L G+ +D ADI+S G Sbjct: 139 NLLLDTNGNLKVSDFGLSALPQEGVELLR-TTCGTPNYVAPEVLSGQGYDGSAADIWSCG 197 Query: 754 IILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPALR 927 +IL+ +L K IN P + ++ +LIHR P P R Sbjct: 198 VILFVILAGYLPFSETDLPGLYRK---INAAEFSCPPWFSAEVKFLIHRILDPNPKTR 252
>Q99ML2:TNK1_MOUSE Non-receptor tyrosine-protein kinase TNK1 - Mus musculus (Mouse)| Length = 666 Score = 98.6 bits (244), Expect = 8e-20 Identities = 74/259 (28%), Positives = 113/259 (43%), Gaps = 19/259 (7%) Frame = +1 Query: 229 RFGKVFKGRCFG--------------LEVAVKIPKVQELSP--EQLEKFKQEVAINSEIN 360 R G++ CFG + VAVK +V P +L F +EV++ ++ Sbjct: 117 RRGELLGSGCFGVVHRGLWTLPSGQSIPVAVKSLRVGPEGPMGTELGDFLREVSVMMKLE 176 Query: 361 HPNVVRFLGACL-KPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYI 537 HP+V+R G L +PL + PL +A R + M Y+ Sbjct: 177 HPHVLRLHGLVLGQPLQMVMELAPLGSLHARLTAPAPTPPLPVALLCLFLRQLAGAMAYL 236 Query: 538 HAANLVHLDLKPENVLLDFNGTAKIADFGLT-VIRLDRQSLLHGGPKGTP-LWMAPEMLL 711 + LVH DL N+LL K+ADFGL + R + GGP+ P W APE L Sbjct: 237 GSCGLVHRDLATRNLLLASPRMIKVADFGLVRPLGGARGRYVMGGPRPIPYAWCAPESLR 296 Query: 712 GKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYL 891 F +D++ FG+ LW++ + ++ + + R P P ++ L L Sbjct: 297 QGAFSSASDVWMFGVTLWEMFSGGEEPWAGVPPYLILQRLEKDRARLPKPPLCSRALYSL 356 Query: 892 IHRCWHPQPALRPSFTEID 948 RCW P PA RPSF+ ++ Sbjct: 357 ALRCWAPHPADRPSFSNLE 375
>P43298:TMK1_ARATH Putative receptor protein kinase TMK1 precursor - Arabidopsis| thaliana (Mouse-ear cress) Length = 942 Score = 98.6 bits (244), Expect = 8e-20 Identities = 60/192 (31%), Positives = 102/192 (53%), Gaps = 8/192 (4%) Frame = +1 Query: 226 GRFGKVFKGRCF-GLEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGACL-- 396 G FG V+KG G ++AVK + ++ + +FK E+A+ +++ H ++V LG CL Sbjct: 597 GGFGVVYKGELHDGTKIAVKRMENGVIAGKGFAEFKSEIAVLTKVRHRHLVTLLGYCLDG 656 Query: 397 --KPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAA---NLVHL 561 K L + + + +PL +R+ +A D+ +G+ Y+H + +H Sbjct: 657 NEKLLVYEYMPQGTLSRHLFEWSEEGLKPLLWKQRLTLALDVARGVEYLHGLAHQSFIHR 716 Query: 562 DLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWMAPEMLLGKPFDEKADI 741 DLKP N+LL + AK+ADFGL + + + + GT ++APE + K D+ Sbjct: 717 DLKPSNILLGDDMRAKVADFGLVRLAPEGKGSIETRIAGTFGYLAPEYAVTGRVTTKVDV 776 Query: 742 YSFGIILWQLLT 777 YSFG+IL +L+T Sbjct: 777 YSFGVILMELIT 788
>Q96S53:TESK2_HUMAN Dual specificity testis-specific protein kinase 2 - Homo sapiens| (Human) Length = 571 Score = 98.6 bits (244), Expect = 8e-20 Identities = 80/251 (31%), Positives = 120/251 (47%), Gaps = 11/251 (4%) Frame = +1 Query: 226 GRFGKVFK--GRCFGLEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGACLK 399 G F +VFK R G +A+K+ LS + K EV + + ++HPN++RF+G C+ Sbjct: 67 GFFSEVFKVRHRASGQVMALKM---NTLSSNRANMLK-EVQLMNRLSHPNILRFMGVCVH 122 Query: 400 PLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDLKPEN 579 +TE + L R+++A DI G+ Y+H + H DL +N Sbjct: 123 QGQLHALTEYINSGNLEQLLDSNLH-LPWTVRVKLAYDIAVGLSYLHFKGIFHRDLTSKN 181 Query: 580 VLL--DFNG-TAKIADFGLTVIRLDRQSLLHGGPK----GTPLWMAPEMLLGKPFDEKAD 738 L+ D NG +A +ADFGL D + G K G+P WMAPE+L +P++EKAD Sbjct: 182 CLIKRDENGYSAVVADFGLAEKIPD---VSMGSEKLAVVGSPFWMAPEVLRDEPYNEKAD 238 Query: 739 IYSFGIILWQLLTR--XXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHP 912 ++S+GIIL +++ R + A + P Q L C + Sbjct: 239 VFSYGIILCEIIARIQADPDYLPRTENFGLDYDAFQHMVGDCPPDFLQ----LTFNCCNM 294 Query: 913 QPALRPSFTEI 945 P LRPSF EI Sbjct: 295 DPKLRPSFVEI 305
>P10421:MOS_MSVTS Serine/threonine-protein kinase-transforming protein mos -| Myeloproliferative sarcoma virus (isolate ts159) Length = 342 Score = 98.6 bits (244), Expect = 8e-20 Identities = 79/259 (30%), Positives = 116/259 (44%), Gaps = 24/259 (9%) Frame = +1 Query: 226 GRFGKVFKGRCFGLEVAVK-IPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGACLKP 402 G FG V+K G+ VA+K + K + F E+ I + + H N+VR + A + Sbjct: 72 GGFGSVYKATYHGVPVAIKQVNKCTKDLRASQRSFWAELNI-ARLRHDNIVRVVAASTRT 130 Query: 403 LN-----FRLVTEXXXXXXXXXXXSNKAR---------PLSLARRMRIARDIVKGMIYIH 540 ++ E R LSL + ++ + D+V G++++H Sbjct: 131 PEDSNSLGTIIMEFGGNVTLHQVIYGATRSPEPLSCREQLSLGKCLKYSLDVVNGLLFLH 190 Query: 541 AANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLD---RQSLLHGGPKGTPLWMAPEMLL 711 + +++HLDLKP N+L+ KI+DFG + D RQS H G GT APE+L Sbjct: 191 SQSILHLDLKPANILISEQDVCKISDFGCSQKLQDLRCRQSPHHIG--GTYTHQAPEILK 248 Query: 712 GKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQG------TN 873 G+ KADIYSFGI LWQ+ TR AV N RP + T Sbjct: 249 GEIATPKADIYSFGITLWQMTTREVPYSGEPQYVQY--AVVAYNLRPSLTGAVFTASLTR 306 Query: 874 QKLSYLIHRCWHPQPALRP 930 + L +I CW + RP Sbjct: 307 KTLQNIIQNCWEARALQRP 325
>O60674:JAK2_HUMAN Tyrosine-protein kinase JAK2 - Homo sapiens (Human)| Length = 1132 Score = 98.6 bits (244), Expect = 8e-20 Identities = 75/291 (25%), Positives = 119/291 (40%), Gaps = 22/291 (7%) Frame = +1 Query: 139 AKGFVGLEIPAEQLIIEEELSKDKDGEDIGRFGKVFKGRCFGLE----VAVKIPKVQELS 306 A GF G + EE K G FG V R L+ V + K+Q + Sbjct: 829 ALGFSGAFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHST 888 Query: 307 PEQLEKFKQEVAINSEINHPNVVRFLGACLKP--LNFRLVTEXXXXXXXXXXXSNKARPL 480 E L F++E+ I + H N+V++ G C N +L+ E + Sbjct: 889 EEHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERI 948 Query: 481 SLARRMRIARDIVKGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLT-VIRLDRQSL 657 + ++ I KGM Y+ +H DL N+L++ KI DFGLT V+ D++ Sbjct: 949 DHIKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYY 1008 Query: 658 LHGGPKGTPL-WMAPEMLLGKPFDEKADIYSFGIILWQLLT--------------RXXXX 792 P +P+ W APE L F +D++SFG++L++L T Sbjct: 1009 KVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGND 1068 Query: 793 XXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPALRPSFTEI 945 + + NN R P P G ++ ++ CW+ RPSF ++ Sbjct: 1069 KQGQMIVFHLIELLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDL 1119 Score = 53.9 bits (128), Expect = 2e-06 Identities = 61/280 (21%), Positives = 117/280 (41%), Gaps = 18/280 (6%) Frame = +1 Query: 160 EIPAEQLIIEEELSKDKDGEDIGRFGKVFKG---------RCFGLEVAVKIPKVQELSPE 312 +I E LI E L + G F K+FKG + EV +K+ + + Sbjct: 539 KIRNEDLIFNESLGQ-------GTFTKIFKGVRREVGDYGQLHETEVLLKV--LDKAHRN 589 Query: 313 QLEKFKQEVAINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLAR 492 E F + ++ S+++H ++V G C+ LV E +++ Sbjct: 590 YSESFFEAASMMSKLSHKHLVLNYGVCVCGDENILVQEFVKFGSLDTYLKKNKNCINILW 649 Query: 493 RMRIARDIVKGMIYIHAANLVHLDLKPENVLL---DFNGTA-----KIADFGLTVIRLDR 648 ++ +A+ + M ++ L+H ++ +N+LL + T K++D G+++ L + Sbjct: 650 KLEVAKQLAWAMHFLEENTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPK 709 Query: 649 QSLLHGGPKGTPLWMAPEMLLG-KPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIK 825 L P W+ PE + K + D +SFG LW++ + ++ Sbjct: 710 DILQERIP-----WVPPECIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQ 764 Query: 826 AVAINNYRPPMPQGTNQKLSYLIHRCWHPQPALRPSFTEI 945 + ++ P P+ +L+ LI+ C +P RPSF I Sbjct: 765 FYE-DRHQLPAPKWA--ELANLINNCMDYEPDFRPSFRAI 801
>P00528:SRC64_DROME Tyrosine-protein kinase Src64B - Drosophila melanogaster (Fruit fly)| Length = 552 Score = 98.2 bits (243), Expect = 1e-19 Identities = 80/283 (28%), Positives = 123/283 (43%), Gaps = 6/283 (2%) Frame = +1 Query: 160 EIPAEQLIIEEELSKDKDGEDIGRFGKVFKGRCFG-LEVAVKIPKVQELSPEQLEKFKQE 336 EIP ++ + +L + G FG+VF G+ ++VAVK + +S F QE Sbjct: 278 EIPRSEIQLLRKLGR-------GNFGEVFYGKWRNSIDVAVKTLREGTMSTAA---FLQE 327 Query: 337 VAINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXX-SNKARPLSLARRMRIARD 513 AI + H +V C + +V E R L + IA Sbjct: 328 AAIMKKFRHNRLVALYAVCSQEEPIYIVQEYMSKGSLLDFLREGDGRYLHFEDLIYIATQ 387 Query: 514 IVKGMIYIHAANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWM 693 + GM Y+ + L+H DL NVL+ N AKI DFGL + D + G + W Sbjct: 388 VASGMEYLESKQLIHRDLAARNVLIGENNVAKICDFGLARVIADDEYCPKQGSRFPVKWT 447 Query: 694 APEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTN 873 APE ++ F K+D++S+GI+L +L T I+ + +R MP+ TN Sbjct: 448 APEAIIYGKFSIKSDVWSYGILLMELFTYGQVPYPGMHSREVIENIE-RGFR--MPKPTN 504 Query: 874 ----QKLSYLIHRCWHPQPALRPSFTEIDNAYLQPIIVETAIP 990 + L+ +CW P RP+F E N Y + V + +P Sbjct: 505 HYFPDNIYQLLLQCWDAVPEKRPTF-EFLNHYFESFSVTSEVP 546
>Q24488:ROR1_DROME Tyrosine-protein kinase transmembrane receptor Ror precursor -| Drosophila melanogaster (Fruit fly) Length = 685 Score = 98.2 bits (243), Expect = 1e-19 Identities = 72/258 (27%), Positives = 117/258 (45%), Gaps = 16/258 (6%) Frame = +1 Query: 226 GRFGKVFKGRCFG-----LEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGA 390 G FGKV+KG+ + VA+K K + S + + FK+E+ + S++ H N+V LG Sbjct: 419 GAFGKVYKGQLLQPNKTTITVAIKALK-ENASVKTQQDFKREIELISDLKHQNIVCILGV 477 Query: 391 CLKP----LNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVH 558 L + F + + + LS ++IA I +GM Y+ A + VH Sbjct: 478 VLNKEPYCMLFEYMANGDLHEFLISNSPTEGKSLSQLEFLQIALQISEGMQYLSAHHYVH 537 Query: 559 LDLKPENVLLDFNGTAKIADFGLT-------VIRLDRQSLLHGGPKGTPLWMAPEMLLGK 717 DL N L++ KI+DFGL+ R+ +SLL WM E +L Sbjct: 538 RDLAARNCLVNEGLVVKISDFGLSRDIYSSDYYRVQSKSLL------PVRWMPSESILYG 591 Query: 718 PFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIH 897 F ++D++SFG++LW++ + I + + P+ + L+ Sbjct: 592 KFTTESDVWSFGVVLWEIYSYGMQPYYGFSNQEVINLIR-SRQLLSAPENCPTAVYSLMI 650 Query: 898 RCWHPQPALRPSFTEIDN 951 CWH Q RP+FT+I N Sbjct: 651 ECWHEQSVKRPTFTDISN 668
>P35739:NTRK1_RAT High affinity nerve growth factor receptor precursor - Rattus| norvegicus (Rat) Length = 799 Score = 98.2 bits (243), Expect = 1e-19 Identities = 77/321 (23%), Positives = 137/321 (42%), Gaps = 23/321 (7%) Frame = +1 Query: 76 AAMQPSAGPGTGAAIH---DPFGVAKGFVGLEIPAEQLIIEEELSKDKDGEDIGRFGKVF 246 +++ P+ G G+G H +P + V I + +I++ EL + G FGKVF Sbjct: 477 SSLSPTEGKGSGLQGHIMENPQYFSDTCVH-HIKRQDIILKWELGE-------GAFGKVF 528 Query: 247 KGRCFGL-----EVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGACLK---- 399 C+ L ++ V + ++E S + F +E + + + H ++VRF G C + Sbjct: 529 LAECYNLLNDQDKMLVAVKALKETSENARQDFHREAELLTMLQHQHIVRFFGVCTEGGPL 588 Query: 400 ----------PLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAAN 549 LN L + PL L + + +A + GM+Y+ + + Sbjct: 589 LMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLASLH 648 Query: 550 LVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPL-WMAPEMLLGKPFD 726 VH DL N L+ KI DFG++ GG P+ WM PE +L + F Sbjct: 649 FVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFS 708 Query: 727 EKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCW 906 ++D++SFG++LW++ T I+ + P+ + ++ CW Sbjct: 709 TESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIECIT-QGRELERPRACPPDVYAIMRGCW 767 Query: 907 HPQPALRPSFTEIDNAYLQPI 969 +P R S ++ +A LQ + Sbjct: 768 QREPQQRLSMKDV-HARLQAL 787
>P57097:MERTK_RAT Proto-oncogene tyrosine-protein kinase MER precursor - Rattus| norvegicus (Rat) Length = 994 Score = 98.2 bits (243), Expect = 1e-19 Identities = 68/254 (26%), Positives = 113/254 (44%), Gaps = 16/254 (6%) Frame = +1 Query: 226 GRFGKVFKGRC-----FGLEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGA 390 G FG V +G +VAVK K+ S ++E+F E A + NHPNV+R LG Sbjct: 591 GEFGSVMEGNLKQEDGTSQKVAVKTMKLDNFSLREIEEFLSEAACMKDFNHPNVIRLLGV 650 Query: 391 CL--------KPLNFRLVTEXXXXXXXXXXXSNKARPLS--LARRMRIARDIVKGMIYIH 540 C+ KP+ + ++ P S L ++ DI +GM Y+ Sbjct: 651 CIELSSQGIPKPMVILPFMKYGDLHTFLLYSRIESVPKSIPLQTLLKFMVDIAQGMEYLS 710 Query: 541 AANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPL-WMAPEMLLGK 717 + N +H DL N +L + T +ADFGL+ G P+ W+A E L + Sbjct: 711 SRNFLHRDLAARNCMLRDDMTVCVADFGLSKKIYSGDYYRQGRIAKMPVKWIAIESLADR 770 Query: 718 PFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIH 897 + K+D+++FG+ +W++ TR + ++ +R P+ L +++ Sbjct: 771 VYTSKSDVWAFGVTMWEIATRGMTPYPGVQNHEMYDYL-LHGHRLKQPEDCLDDLYEIMY 829 Query: 898 RCWHPQPALRPSFT 939 CW P RP+F+ Sbjct: 830 SCWSADPLDRPTFS 843
>Q60805:MERTK_MOUSE Proto-oncogene tyrosine-protein kinase MER precursor - Mus musculus| (Mouse) Length = 994 Score = 98.2 bits (243), Expect = 1e-19 Identities = 67/254 (26%), Positives = 111/254 (43%), Gaps = 16/254 (6%) Frame = +1 Query: 226 GRFGKVFKGRC-----FGLEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGA 390 G FG V +G +VAVK K+ S ++E+F E A + NHPNV+R LG Sbjct: 591 GEFGSVMEGNLKQEDGTSQKVAVKTMKLDNFSQREIEEFLSEAACMKDFNHPNVIRLLGV 650 Query: 391 CL--------KPLNFRLVTEXXXXXXXXXXXSNKARP--LSLARRMRIARDIVKGMIYIH 540 C+ KP+ + P + L ++ DI +GM Y+ Sbjct: 651 CIELSSQGIPKPMVILPFMKYGDLHTFLLYSRLNTGPKYIHLQTLLKFMMDIAQGMEYLS 710 Query: 541 AANLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPL-WMAPEMLLGK 717 N +H DL N +L + T +ADFGL+ G P+ W+A E L + Sbjct: 711 NRNFLHRDLAARNCMLRDDMTVCVADFGLSKKIYSGDYYRQGRIAKMPVKWIAIESLADR 770 Query: 718 PFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIH 897 + K+D+++FG+ +W++ TR + ++ +R P+ +L +++ Sbjct: 771 VYTSKSDVWAFGVTMWEITTRGMTPYPGVQNHEMYDYL-LHGHRLKQPEDCLDELYDIMY 829 Query: 898 RCWHPQPALRPSFT 939 CW P RP+F+ Sbjct: 830 SCWSADPLDRPTFS 843
>P53671:LIMK2_HUMAN LIM domain kinase 2 - Homo sapiens (Human)| Length = 638 Score = 98.2 bits (243), Expect = 1e-19 Identities = 72/282 (25%), Positives = 125/282 (44%), Gaps = 23/282 (8%) Frame = +1 Query: 214 GEDIGR--FGKVFKGRCFGLEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLG 387 GE +G+ FG+ K + + ++ E + F EV + ++HPNV++F+G Sbjct: 334 GEVLGKGFFGQAIKVTHKATGKVMVMKELIRCDEETQKTFLTEVKVMRSLDHPNVLKFIG 393 Query: 388 ACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDL 567 K L+TE + P +++R A+ I GM Y+H+ ++H DL Sbjct: 394 VLYKDKKLNLLTEYIEGGTLKDFLRSMD-PFPWQQKVRFAKGIASGMAYLHSMCIIHRDL 452 Query: 568 KPENVLLDFNGTAKIADFGLTVIRLD-------------RQSLLHGGPK------GTPLW 690 N L+ + T +ADFGL+ + ++ +++L K G P W Sbjct: 453 NSHNCLIKLDKTVVVADFGLSRLIVEERKRAPMEKATTKKRTLRKNDRKKRYTVVGNPYW 512 Query: 691 MAPEMLLGKPFDEKADIYSFGIILWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGT 870 MAPEML GK +DE DI+SFGI+L +++ + + +P Sbjct: 513 MAPEMLNGKSYDETVDIFSFGIVLCEIIGQVYADPDCLPRTLDFGLNVKLFWEKFVPTDC 572 Query: 871 NQKLSYLIHRCWHPQPALRPSFTEIDNAY--LQPIIVETAIP 990 L C +P RP+F+++++++ L + E IP Sbjct: 573 PPAFFPLAAICCRLEPESRPAFSKLEDSFEALSLYLGELGIP 614
>Q03526:ITK_MOUSE Tyrosine-protein kinase ITK/TSK - Mus musculus (Mouse)| Length = 625 Score = 98.2 bits (243), Expect = 1e-19 Identities = 59/240 (24%), Positives = 113/240 (47%) Frame = +1 Query: 226 GRFGKVFKGRCFGLEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGACLKPL 405 G+FG V G + V I +QE + + E F +E + +++HP +V+ G CL+ Sbjct: 377 GQFGLVHLGYWLNKD-KVAIKTIQEGAMSE-EDFIEEAEVMMKLSHPKLVQLYGVCLEQA 434 Query: 406 NFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDLKPENVL 585 LV E ++ + + + D+ +GM Y+ A ++H DL N L Sbjct: 435 PICLVFEFMEHGCLSDYLRSQRGLFAAETLLGMCLDVCEGMAYLEKACVIHRDLAARNCL 494 Query: 586 LDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWMAPEMLLGKPFDEKADIYSFGIILW 765 + N K++DFG+T LD Q G K W +PE+ + K+D++SFG+++W Sbjct: 495 VGENQVIKVSDFGMTRFVLDDQYTSSTGTKFPVKWASPEVFSFSRYSSKSDVWSFGVLMW 554 Query: 766 QLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPALRPSFTEI 945 ++ + ++ ++ +R P+ + + +++ CW +P RP F+++ Sbjct: 555 EVFSEGKIPYENRSNSEVVEDIS-TGFRLYKPRLASCHVYQIMNHCWKEKPEDRPPFSQL 613
>Q08881:ITK_HUMAN Tyrosine-protein kinase ITK/TSK - Homo sapiens (Human)| Length = 620 Score = 98.2 bits (243), Expect = 1e-19 Identities = 59/241 (24%), Positives = 112/241 (46%), Gaps = 1/241 (0%) Frame = +1 Query: 226 GRFGKVFKGRCFGLE-VAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGACLKP 402 G+FG V G + VA+K + +S E F +E + +++HP +V+ G CL+ Sbjct: 372 GQFGLVHLGYWLNKDKVAIKTIREGAMSEED---FIEEAEVMMKLSHPKLVQLYGVCLEQ 428 Query: 403 LNFRLVTEXXXXXXXXXXXSNKARPLSLARRMRIARDIVKGMIYIHAANLVHLDLKPENV 582 LV E + + + + D+ +GM Y+ A ++H DL N Sbjct: 429 APICLVFEFMEHGCLSDYLRTQRGLFAAETLLGMCLDVCEGMAYLEEACVIHRDLAARNC 488 Query: 583 LLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWMAPEMLLGKPFDEKADIYSFGIIL 762 L+ N K++DFG+T LD Q G K W +PE+ + K+D++SFG+++ Sbjct: 489 LVGENQVIKVSDFGMTRFVLDDQYTSSTGTKFPVKWASPEVFSFSRYSSKSDVWSFGVLM 548 Query: 763 WQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPALRPSFTE 942 W++ + ++ ++ +R P+ + + +++ CW +P RP+F+ Sbjct: 549 WEVFSEGKIPYENRSNSEVVEDIS-TGFRLYKPRLASTHVYQIMNHCWKERPEDRPAFSR 607 Query: 943 I 945 + Sbjct: 608 L 608
>P32577:CSK_RAT Tyrosine-protein kinase CSK - Rattus norvegicus (Rat)| Length = 450 Score = 98.2 bits (243), Expect = 1e-19 Identities = 69/242 (28%), Positives = 109/242 (45%), Gaps = 2/242 (0%) Frame = +1 Query: 226 GRFGKVFKGRCFGLEVAVKIPKVQELSPEQLEKFKQEVAINSEINHPNVVRFLGACLKPL 405 G FG V G G +VAVK K + + F E ++ +++ H N+V+ LG ++ Sbjct: 204 GEFGDVMLGDYRGNKVAVKCIK----NDATAQAFLAEASVMTQLRHSNLVQLLGVIVEEK 259 Query: 406 N-FRLVTEXXXXXXXXXXXSNKARP-LSLARRMRIARDIVKGMIYIHAANLVHLDLKPEN 579 +VTE ++ R L ++ + D+ + M Y+ N VH DL N Sbjct: 260 GGLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLEGNNFVHRDLAARN 319 Query: 580 VLLDFNGTAKIADFGLTVIRLDRQSLLHGGPKGTPLWMAPEMLLGKPFDEKADIYSFGII 759 VL+ + AK++DFGLT S K W APE L K F K+D++SFGI+ Sbjct: 320 VLVSEDNVAKVSDFGLT----KEASSTQDTGKLPVKWTAPEALREKKFSTKSDVWSFGIL 375 Query: 760 LWQLLTRXXXXXXXXXXXXXIKAVAINNYRPPMPQGTNQKLSYLIHRCWHPQPALRPSFT 939 LW++ + + V Y+ P G + ++ CWH A RP+F Sbjct: 376 LWEIYSFGRVPYPRIPLKDVVPRVE-KGYKMDAPDGCPPAVYDVMKNCWHLDAATRPTFL 434 Query: 940 EI 945 ++ Sbjct: 435 QL 436 Score = 35.8 bits (81), Expect = 0.62 Identities = 20/57 (35%), Positives = 31/57 (54%) Frame = +1 Query: 1417 PWFYGDLDKDAAFELLRNKQPGTFLVRFSSNPEHVGFVISVVDHKNTVVHIRVKHNA 1587 PWF+G + ++ A LL + G FLVR S+N + G V + V H R+ ++A Sbjct: 81 PWFHGKITREQAERLLYPPETGLFLVRESTN--YPGDYTLCVSCEGKVEHYRIMYHA 135
>Q9S9M1:WAKLE_ARATH Wall-associated receptor kinase-like 5 precursor - Arabidopsis| thaliana (Mouse-ear cress) Length = 731 Score = 97.8 bits (242), Expect = 1e-19 Identities = 71/217 (32%), Positives = 112/217 (51%), Gaps = 12/217 (5%) Frame = +1 Query: 163 IPAEQLIIEEELSKDKDGEDIGRF------GKVFKGRCF-GLEVAVKIPKVQELSPEQLE 321 + +L EEL K D + R G V+KG G +AVK KV + ++LE Sbjct: 414 VDMSRLFSSEELKKATDNFSVKRVLGKGSQGTVYKGMMVDGKIIAVKRSKV--VDEDKLE 471 Query: 322 KFKQEVAINSEINHPNVVRFLGACLKPLNFRLVTEXXXXXXXXXXXSNKARPLSLA--RR 495 KF E+ + S+INH N+V+ +G CL+ LV E +++ ++ R Sbjct: 472 KFINEIILLSQINHRNIVKLIGCCLETEVPILVYEYIPNGDMFKRLHDESDDYAMTWEVR 531 Query: 496 MRIARDIVKGMIYIHAA---NLVHLDLKPENVLLDFNGTAKIADFGLTVIRLDRQSLLHG 666 +RIA +I + Y+H+A + H D+K N+LLD AK++DFG + Q+ L Sbjct: 532 LRIAIEIAGALTYMHSAASFPIYHRDIKTTNILLDEKYGAKVSDFGTSRSVTIDQTHLTT 591 Query: 667 GPKGTPLWMAPEMLLGKPFDEKADIYSFGIILWQLLT 777 GT +M PE L + +K+D+YSFG++L +L+T Sbjct: 592 MVAGTFGYMDPEYFLSSQYTDKSDVYSFGVVLVELIT 628 Database: uniprot_sprot.fasta.out Posted date: Jul 19, 2007 5:58 PM Number of letters in database: 100,686,439 Number of sequences in database: 274,295 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 274295 Number of Hits to DB: 284,386,709 Number of extensions: 6045924 Number of successful extensions: 25884 Number of sequences better than 10.0: 2632 Number of HSP's gapped: 22752 Number of HSP's successfully gapped: 2826 Length of query: 611 Length of database: 100,686,439 Length adjustment: 119 Effective length of query: 492 Effective length of database: 68,045,334 Effective search space: 33478304328 Effective search space used: 33478304328 Neighboring words threshold: 12 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
