ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
Japanese | English
更新日：2016年5月1日

Clone Information

BLAST Search Result

Clone Name FLbaf111n03
Clone Library Name barley_pub
No. Definition Score
(bits)		 E
Value
1Q94A68:Y1669_ARATH Putative oxidoreductase At1g06690, chloroplas... 235 3e-61
2P63485:Y2320_MYCBO Uncharacterized oxidoreductase Mb2320 - Mycob... 119 4e-26
3P63484:Y2298_MYCTU Uncharacterized oxidoreductase Rv2298/MT2355 ... 119 4e-26
4P80874:GS69_BACSU General stress protein 69 - Bacillus subtilis 102 5e-21
5Q27955:KCAB2_BOVIN Voltage-gated potassium channel subunit beta-... 96 3e-19
6P77735:YAJO_ECOLI Uncharacterized oxidoreductase yajO - Escheric... 96 3e-19
7P62483:KCAB2_RAT Voltage-gated potassium channel subunit beta-2 ... 96 4e-19
8P62482:KCAB2_MOUSE Voltage-gated potassium channel subunit beta-... 96 4e-19
9Q13303:KCAB2_HUMAN Voltage-gated potassium channel subunit beta-... 95 6e-19
10Q9PTM5:KCAB2_XENLA Voltage-gated potassium channel subunit beta-... 95 7e-19
11P46905:YCCK_BACSU Uncharacterized oxidoreductase yccK - Bacillus... 94 1e-18
12Q9PTM4:KCAB3_XENLA Voltage-gated potassium channel subunit beta-... 94 1e-18
13O43448:KCAB3_HUMAN Voltage-gated potassium channel subunit beta-... 91 1e-17
14Q09923:YAKC_SCHPO Aldo-keto reductase yakc [NADP+] - Schizosacch... 91 1e-17
15Q9XT31:KCAB1_RABIT Voltage-gated potassium channel subunit beta-... 91 1e-17
16Q14722:KCAB1_HUMAN Voltage-gated potassium channel subunit beta-... 91 1e-17
17Q40648:KCAB_ORYSJ Probable voltage-gated potassium channel subun... 90 2e-17
18P63144:KCAB1_RAT Voltage-gated potassium channel subunit beta-1 ... 90 2e-17
19Q28528:KCAB1_MUSPU Voltage-gated potassium channel subunit beta-... 90 2e-17
20P63143:KCAB1_MOUSE Voltage-gated potassium channel subunit beta-... 90 2e-17
21Q4PJK1:KCAB1_BOVIN Voltage-gated potassium channel subunit beta-... 90 2e-17
22Q9PWR1:KCAB1_CHICK Voltage-gated potassium channel subunit beta-... 89 3e-17
23Q7G764:NADO1_ORYSJ Probable NAD(P)H-dependent oxidoreductase 1 -... 86 3e-16
24Q63494:KCAB3_RAT Voltage-gated potassium channel subunit beta-3 ... 86 4e-16
25Q46851:YGHZ_ECOLI Uncharacterized protein yghZ - Escherichia coli 85 8e-16
26Q7G765:NADO2_ORYSJ Probable NAD(P)H-dependent oxidoreductase 2 -... 85 8e-16
27Q8X529:YGHZ_ECO57 Uncharacterized protein yghZ - Escherichia col... 84 1e-15
28P46336:IOLS_BACSU Protein iolS - Bacillus subtilis 84 1e-15
29O14295:PLR1_SCHPO Pyridoxal reductase - Schizosaccharomyces pomb... 84 2e-15
30P76234:YEAE_ECOLI Uncharacterized protein yeaE - Escherichia coli 82 5e-15
31P0A9T5:TAS_SHIFL Protein tas - Shigella flexneri 82 5e-15
32P0A9T4:TAS_ECOLI Protein tas - Escherichia coli 82 5e-15
33P26690:6DCS_SOYBN NAD(P)H-dependent 6'-deoxychalcone synthase - ... 82 6e-15
34P77256:YDJG_ECOLI Uncharacterized oxidoreductase ydjG - Escheric... 81 1e-14
35P40691:A115_TOBAC Auxin-induced protein PCNT115 - Nicotiana taba... 81 1e-14
36P80276:ALDR_PIG Aldose reductase - Sus scrofa (Pig) 77 1e-13
37P07943:ALDR_RAT Aldose reductase - Rattus norvegicus (Rat) 73 3e-12
38P16116:ALDR_BOVIN Aldose reductase - Bos taurus (Bovine) 73 3e-12
39Q8XBT6:DKGA_ECO57 2,5-diketo-D-gluconic acid reductase A - Esche... 72 7e-12
40P47137:YJ66_YEAST Probable oxidoreductase YJR096W - Saccharomyce... 71 9e-12
41P58744:DKGA_SALTI 2,5-diketo-D-gluconic acid reductase A - Salmo... 71 9e-12
42P28475:S6PD_MALDO NADP-dependent D-sorbitol-6-phosphate dehydrog... 71 1e-11
43P15121:ALDR_HUMAN Aldose reductase - Homo sapiens (Human) 70 1e-11
44Q8VC28:AK1CD_MOUSE Aldo-keto reductase family 1 member C13 - Mus... 70 1e-11
45P50578:AK1A1_PIG Alcohol dehydrogenase [NADP+] - Sus scrofa (Pig) 70 2e-11
46Q09632:YOF5_CAEEL Probable oxidoreductase ZK1290.5 - Caenorhabdi... 69 3e-11
47P51635:AK1A1_RAT Alcohol dehydrogenase [NADP+] - Rattus norvegic... 69 4e-11
48Q46857:DKGA_ECOLI 2,5-diketo-D-gluconic acid reductase A - Esche... 69 6e-11
49P45376:ALDR_MOUSE Aldose reductase - Mus musculus (Mouse) 69 6e-11
50Q8ZM06:DKGA_SALTY 2,5-diketo-D-gluconic acid reductase A - Salmo... 68 7e-11
51P15122:ALDR_RABIT Aldose reductase - Oryctolagus cuniculus (Rabbit) 68 1e-10
52P45377:ALD2_MOUSE Aldose reductase-related protein 2 - Mus muscu... 67 2e-10
53P06632:DKGA_CORSC 2,5-diketo-D-gluconic acid reductase A - Coryn... 67 2e-10
54P23901:ALDR_HORVU Aldose reductase - Hordeum vulgare (Barley) 66 3e-10
55P21300:ALD1_MOUSE Aldose reductase-related protein 1 - Mus muscu... 66 3e-10
56Q9JII6:AK1A1_MOUSE Alcohol dehydrogenase [NADP+] - Mus musculus ... 66 4e-10
57P14550:AK1A1_HUMAN Alcohol dehydrogenase [NADP+] - Homo sapiens ... 66 4e-10
58Q02895:YP088_YEAST Putative aryl-alcohol dehydrogenase YPL088W -... 65 5e-10
59P15339:DKGB_CORSS 2,5-diketo-D-gluconic acid reductase B - Coryn... 65 5e-10
60O08782:ALD2_CRIGR Aldose reductase-related protein 2 - Cricetulu... 65 5e-10
61O60218:AK1BA_HUMAN Aldo-keto reductase family 1 member B10 - Hom... 65 6e-10
62Q3ZCJ2:AK1A1_BOVIN Alcohol dehydrogenase [NADP+] - Bos taurus (B... 65 6e-10
63Q00049:NORA_ASPFL Norsolorinic acid reductase - Aspergillus flavus 65 8e-10
64Q00258:NORA_ASPPA Norsolorinic acid reductase - Aspergillus para... 64 2e-09
65P05980:PGFS1_BOVIN Prostaglandin-F synthase 1 - Bos taurus (Bovine) 63 2e-09
66P52897:PGFS2_BOVIN Prostaglandin-F synthase 2 - Bos taurus (Bovine) 63 3e-09
67P22045:P100_LEIMA Probable reductase - Leishmania major 63 3e-09
68Q96JD6:AKCL2_HUMAN Aldo-keto reductase family 1 member C-like pr... 62 4e-09
69Q9P8R5:XYL1_ASPNG NAD(P)H-dependent D-xylose reductase - Aspergi... 62 5e-09
70Q8ZI40:DKGA_YERPE 2,5-diketo-D-gluconic acid reductase A - Yersi... 61 9e-09
71Q06494:PLR1_YEAST Putative pyridoxal reductase - Saccharomyces c... 61 1e-08
72Q9DCT1:AK1E1_MOUSE Aldo-keto reductase family 1 member E1 - Mus ... 61 1e-08
73P70694:DHB5_MOUSE Estradiol 17 beta-dehydrogenase 5 - Mus muscul... 60 2e-08
74Q8CG45:ARK72_RAT Aflatoxin B1 aldehyde reductase member 2 - Ratt... 60 2e-08
75P52898:DDBX_BOVIN Dihydrodiol dehydrogenase 3 - Bos taurus (Bovine) 60 2e-08
76P49249:IN22_MAIZE IN2-2 protein - Zea mays (Maize) 60 3e-08
77P54569:YQKF_BACSU Uncharacterized oxidoreductase yqkF - Bacillus... 59 3e-08
78P40690:ALKE_BABBO Aldo-keto reductase - Babesia bovis 59 3e-08
79P25906:YDBC_ECOLI Putative oxidoreductase ydbC - Escherichia coli 58 1e-07
80P31867:XYL1_PICST NAD(P)H-dependent D-xylose reductase - Pichia ... 57 1e-07
81Q876L8:XYL1_TRIRE NAD(P)H-dependent D-xylose reductase - Trichod... 55 5e-07
82P87039:XYL2_CANTR NADPH-dependent D-xylose reductase II,III - Ca... 55 6e-07
83Q8CG76:ARK72_MOUSE Aflatoxin B1 aldehyde reductase member 2 - Mu... 55 6e-07
84Q4R802:AKCL2_MACFA Aldo-keto reductase family 1 member C-like pr... 55 6e-07
85P17264:CRO_RANCA Rho crystallin - Rana catesbeiana (Bull frog) 55 8e-07
86P82809:AK1CD_MESAU Aldo-keto reductase family 1 member C13 - Mes... 55 8e-07
87O94735:XYL1_PICGU NADPH-dependent D-xylose reductase - Pichia gu... 54 1e-06
88P80508:PE2R_RABIT Prostaglandin-E(2) 9-reductase - Oryctolagus c... 54 1e-06
89P02532:CRO_RANTE Rho crystallin - Rana temporaria (European comm... 54 1e-06
90O70473:AK1A1_CRIGR Alcohol dehydrogenase [NADP+] - Cricetulus gr... 54 1e-06
91Q8NHP1:ARK74_HUMAN Aflatoxin B1 aldehyde reductase member 4 - Ho... 54 2e-06
92P27800:ALDX_SPOSA Aldehyde reductase 1 - Sporobolomyces salmonic... 54 2e-06
93P51857:AK1D1_HUMAN 3-oxo-5-beta-steroid 4-dehydrogenase - Homo s... 54 2e-06
94P97382:KCAB3_MOUSE Voltage-gated potassium channel subunit beta-... 53 3e-06
95P38918:ARK73_RAT Aflatoxin B1 aldehyde reductase member 3 - Ratt... 52 5e-06
96O43488:ARK72_HUMAN Aflatoxin B1 aldehyde reductase member 2 - Ho... 52 7e-06
97P14065:GCY_YEAST Protein GCY - Saccharomyces cerevisiae (Baker's... 51 9e-06
98P31210:AK1D1_RAT 3-oxo-5-beta-steroid 4-dehydrogenase - Rattus n... 51 9e-06
99O13283:XYL1_CANTR NAD(P)H-dependent D-xylose reductase I,II - Ca... 51 1e-05
100P17516:AK1C4_HUMAN Aldo-keto reductase family 1 member C4 - Homo... 50 2e-05
101Q8VCX1:AK1D1_MOUSE 3-oxo-5-beta-steroid 4-dehydrogenase - Mus mu... 50 3e-05
102Q9TV64:AK1D1_RABIT 3-oxo-5-beta-steroid 4-dehydrogenase - Orycto... 49 6e-05
103Q04828:AK1C1_HUMAN Aldo-keto reductase family 1 member C1 - Homo... 49 6e-05
104P30863:DKGB_ECOLI 2,5-diketo-D-gluconic acid reductase B - Esche... 48 8e-05
105Q95JH5:AK1C4_MACFA Aldo-keto reductase family 1 member C4 - Maca... 48 8e-05
106Q95JH6:AK1C1_MACFU Aldo-keto reductase family 1 member C1 homolo... 48 8e-05
107Q9P430:XYL1_CANSH NAD(P)H-dependent D-xylose reductase - Candida... 48 1e-04
108Q5REQ0:AK1C1_PONPY Aldo-keto reductase family 1 member C1 homolo... 48 1e-04
109Q12458:YPR1_YEAST Putative reductase 1 - Saccharomyces cerevisia... 47 1e-04
110Q6Y0Z3:XYL1_CANPA NADH-dependent D-xylose reductase - Candida pa... 47 1e-04
111P52895:AK1C2_HUMAN Aldo-keto reductase family 1 member C2 - Homo... 47 1e-04
112P49378:XYL1_KLULA NAD(P)H-dependent D-xylose reductase - Kluyver... 47 2e-04
113Q95JH7:AK1C1_MACFA Aldo-keto reductase family 1 member C1 homolo... 47 2e-04
114Q95JH4:AK1C4_MACFU Aldo-keto reductase family 1 member C4 - Maca... 47 2e-04
115Q8X7Z7:DKGB_ECO57 2,5-diketo-D-gluconic acid reductase B - Esche... 46 3e-04
116O95154:ARK73_HUMAN Aflatoxin B1 aldehyde reductase member 3 - Ho... 45 7e-04
117P51652:AKC1H_RAT Aldo-keto reductase family 1 member C18 - Rattu... 45 9e-04
118O74237:XYL1_CANTE NAD(P)H-dependent D-xylose reductase - Candida... 44 0.001
119Q5R7C9:AK1C3_PONPY Aldo-keto reductase family 1 member C3 homolo... 44 0.001
120Q01752:AAD_PHACH Aryl-alcohol dehydrogenase [NADP+] - Phanerocha... 44 0.002
121Q10494:YDG7_SCHPO Probable oxidoreductase C26F1.07 - Schizosacch... 43 0.003
122Q07551:KAR_YEAST NADPH-dependent alpha-keto amide reductase - Sa... 42 0.004
123P42330:AK1C3_HUMAN Aldo-keto reductase family 1 member C3 - Homo... 42 0.006
124P42972:YCSN_BACSU Uncharacterized oxidoreductase ycsN - Bacillus... 42 0.007
125Q01213:DTDH_MUCMU 4-dihydromethyl-trisporate dehydrogenase - Muc... 41 0.013
126Q8ZRM7:DKGB_SALTY 2,5-diketo-D-gluconic acid reductase B - Salmo... 41 0.013
127Q8Z988:DKGB_SALTI 2,5-diketo-D-gluconic acid reductase B - Salmo... 41 0.013
128P23457:DIDH_RAT 3-alpha-hydroxysteroid dehydrogenase - Rattus no... 41 0.013
129Q8K023:AKC1H_MOUSE Aldo-keto reductase family 1 member C18 - Mus... 41 0.013
130P38115:ARA1_YEAST D-arabinose dehydrogenase [NAD(P)+] heavy chai... 39 0.048
131Q01333:YCR4_ESCVU Hypothetical 11.2 kDa protein in crtE 3'region... 37 0.14
132P38715:GRE3_YEAST NADPH-dependent aldose reductase GRE3 - Saccha... 37 0.18
133P78736:XYL1_PACTA NAD(P)H-dependent D-xylose reductase - Pachyso... 36 0.31
134Q5T2L2:AKCL1_HUMAN Aldo-keto reductase family 1 member C-like pr... 34 1.2
135Q76KC2:PLD_MICLT Pyridoxal 4-dehydrogenase - Microbacterium lute... 33 2.6
136Q04212:ARA2_YEAST D-arabinose 1-dehydrogenase - Saccharomyces ce... 33 2.6
137P39016:MPT5_YEAST Suppressor protein MPT5 - Saccharomyces cerevi... 32 7.7
138P43561:FET5_YEAST Iron transport multicopper oxidase FET5 precur... 32 7.7
139Q7N2T7:COBQ_PHOLL Cobyric acid synthase - Photorhabdus luminesce... 32 7.7
140Q8RAZ3:CHEB_THETN Chemotaxis response regulator protein-glutamat... 32 7.7 
>Q94A68:Y1669_ARATH Putative oxidoreductase At1g06690, chloroplast precursor -|
            Arabidopsis thaliana (Mouse-ear cress)
          Length = 377
 Score =  235 bits (600), Expect = 3e-61
 Identities = 135/327 (41%), Positives = 188/327 (57%), Gaps = 13/327 (3%)
 Frame = +2

Query: 197  KVNVGPLSVSPMGFGTWAWGNQLLWGYEESMDSELQEC---FNLALKNGINLFDTADSYG 367
            K+    L V+ +G G W+WG+   W   +  D +L+     F+ +L NGI+ FDTA+ YG
Sbjct: 50   KLGGSDLKVTKLGIGVWSWGDNSYWNDFQWDDRKLKAAKGAFDTSLDNGIDFFDTAEVYG 109

Query: 368  TGKLNG--QSERLLGKFIRECQGPIKSPDDVVIATKFAAYPWRLTSGQFVNACRSSLERL 541
            +    G   SE LLG+FIRE +      + V +ATKFAA PWR      V A + SL RL
Sbjct: 110  SKFSLGAISSETLLGRFIRERKERYPGAE-VSVATKFAALPWRFGRESVVTALKDSLSRL 168

Query: 542  QIDRLGIGQLHWSTANYAPLQERALW------DGLVEMYDKGLVRAVGVSNYGPKQLLKI 703
            ++  + + QLHW            LW      DGL +  ++GLV+AVGVSNY  K+L   
Sbjct: 169  ELSSVDLYQLHWP----------GLWGNEGYLDGLGDAVEQGLVKAVGVSNYSEKRLRDA 218

Query: 704  HSYLASRGVPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGMLTGKYDASN 883
            +  L  RG+PL+S QV +SL+    EQ  +K  CD LGV LIAYSP+  G LTGKY   N
Sbjct: 219  YERLKKRGIPLASNQVNYSLIYRAPEQTGVKAACDELGVTLIAYSPIAQGALTGKYTPEN 278

Query: 884  LPNGPRSVLF-RQILPGLESLLSCLKSIADRKGKTMSQVAINWCICKG-AIPIPGVKTVR 1057
             P+GPR  ++ R+ L  L+ LL+ +K I +   KT +Q+A+NW + +G  IPIPG K   
Sbjct: 279  PPSGPRGRIYTREFLTKLQPLLNRIKQIGENYSKTPTQIALNWLVAQGNVIPIPGAKNAE 338

Query: 1058 HVEDNLGALGWRLSPGEISELEAAAME 1138
              ++  GA+GW L+  E+SEL + A E
Sbjct: 339  QAKEFAGAIGWSLTDNEVSELRSLASE 365
to top
>P63485:Y2320_MYCBO Uncharacterized oxidoreductase Mb2320 - Mycobacterium bovis|
          Length = 323

 Score =  119 bits (297), Expect = 4e-26
 Identities = 102/309 (33%), Positives = 155/309 (50%), Gaps = 5/309 (1%)
 Frame = +2

Query: 221  VSPMGFGTWAWGNQLLWGY-EESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQSER 397
            VS +G GTW +G++  WGY +       ++    A   G+ LFDTA+ YG GK    SER
Sbjct: 12   VSRIGLGTWQFGSRE-WGYGDRYATGAARDIVKRARALGVTLFDTAEIYGLGK----SER 66

Query: 398  LLGKFIRECQGPIKSPDDVVIATKFAAYPWRLTSGQFVNACRSSLERLQIDRLGIGQLHW 577
            +LG+ + + +       +VV+A+K   +P         N  R+S  RLQ++R+ + Q+H 
Sbjct: 67   ILGEALGDDR------TEVVVASK--VFPVAPFPAVIKNRERASARRLQLNRIPLYQIHQ 118

Query: 578  STANYAPLQERALWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSYLASRGVPLSSAQVQF 757
                   + +  +  G+ ++ D G + A GVSNY   +  K  + L   G P+ S QV F
Sbjct: 119  PNP---VVPDSVIMPGMRDLLDSGDIGAAGVSNYSLARWRKADAAL---GRPVVSNQVHF 172

Query: 758  SLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGMLTGKYDASNLPNGPRSV--LF-RQILP 928
            SL +  +   +L    +     +IAYSPL  G+L GKY   N P G R++  LF  + L 
Sbjct: 173  SL-AHPDALEDLVPFAELENRIVIAYSPLAQGLLGGKYGLENRPGGVRALNPLFGTENLR 231

Query: 929  GLESLLSCLKSIADRKGKTMSQVAINWCI-CKGAIPIPGVKTVRHVEDNLGALGWRLSPG 1105
             +E LL+ L++IA       +QVA+ W I   G + IPG  +V  +E N+ A    LS  
Sbjct: 232  RIEPLLATLRAIAVDVDAKPAQVALAWLISLPGVVAIPGASSVEQLEFNVAAADIELSAQ 291

Query: 1106 EISELEAAA 1132
                L  AA
Sbjct: 292  SRDALTDAA 300
to top
>P63484:Y2298_MYCTU Uncharacterized oxidoreductase Rv2298/MT2355 - Mycobacterium|
            tuberculosis
          Length = 323

 Score =  119 bits (297), Expect = 4e-26
 Identities = 102/309 (33%), Positives = 155/309 (50%), Gaps = 5/309 (1%)
 Frame = +2

Query: 221  VSPMGFGTWAWGNQLLWGY-EESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQSER 397
            VS +G GTW +G++  WGY +       ++    A   G+ LFDTA+ YG GK    SER
Sbjct: 12   VSRIGLGTWQFGSRE-WGYGDRYATGAARDIVKRARALGVTLFDTAEIYGLGK----SER 66

Query: 398  LLGKFIRECQGPIKSPDDVVIATKFAAYPWRLTSGQFVNACRSSLERLQIDRLGIGQLHW 577
            +LG+ + + +       +VV+A+K   +P         N  R+S  RLQ++R+ + Q+H 
Sbjct: 67   ILGEALGDDR------TEVVVASK--VFPVAPFPAVIKNRERASARRLQLNRIPLYQIHQ 118

Query: 578  STANYAPLQERALWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSYLASRGVPLSSAQVQF 757
                   + +  +  G+ ++ D G + A GVSNY   +  K  + L   G P+ S QV F
Sbjct: 119  PNP---VVPDSVIMPGMRDLLDSGDIGAAGVSNYSLARWRKADAAL---GRPVVSNQVHF 172

Query: 758  SLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGMLTGKYDASNLPNGPRSV--LF-RQILP 928
            SL +  +   +L    +     +IAYSPL  G+L GKY   N P G R++  LF  + L 
Sbjct: 173  SL-AHPDALEDLVPFAELENRIVIAYSPLAQGLLGGKYGLENRPGGVRALNPLFGTENLR 231

Query: 929  GLESLLSCLKSIADRKGKTMSQVAINWCI-CKGAIPIPGVKTVRHVEDNLGALGWRLSPG 1105
             +E LL+ L++IA       +QVA+ W I   G + IPG  +V  +E N+ A    LS  
Sbjct: 232  RIEPLLATLRAIAVDVDAKPAQVALAWLISLPGVVAIPGASSVEQLEFNVAAADIELSAQ 291

Query: 1106 EISELEAAA 1132
                L  AA
Sbjct: 292  SRDALTDAA 300
to top
>P80874:GS69_BACSU General stress protein 69 - Bacillus subtilis|
          Length = 331

 Score =  102 bits (253), Expect = 5e-21
 Identities = 92/313 (29%), Positives = 146/313 (46%), Gaps = 18/313 (5%)
 Frame = +2

Query: 215  LSVSPMGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQSE 394
            +  S +G GTWA G  +  G +E    E       AL  GI L DTA +YG G    QSE
Sbjct: 11   IEASRIGLGTWAIGGTMWGGTDEKTSIET---IRAALDQGITLIDTAPAYGFG----QSE 63

Query: 395  RLLGKFIRECQGPIKSPDDVVIATKFAAYPWR-------LTSGQFVNACRSSLERLQIDR 553
             ++GK I+E        D V++ATK  A  W+           + V    +SL+RLQ D 
Sbjct: 64   EIVGKAIKE----YGKRDQVILATK-TALDWKNNQLFRHANRARIVEEVENSLKRLQTDY 118

Query: 554  LGIGQLHWSTANYAPLQERALWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSYLASRGVP 733
            + + Q+HW      P++E A  + + E+YD G +RA+GVSN+  +Q+    +       P
Sbjct: 119  IDLYQVHWPDP-LVPIEETA--EVMKELYDAGKIRAIGVSNFSIEQMDTFRAV-----AP 170

Query: 734  LSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGMLTGK------YDASNLPNG 895
            L + Q  ++L     E+  L    D+  +  + Y  L  G+LTGK      ++  +L N 
Sbjct: 171  LHTIQPPYNLFEREMEESVLPYAKDN-KITTLLYGSLCRGLLTGKMTEEYTFEGDDLRNH 229

Query: 896  P---RSVLFRQILPGLESLLSCLKSIADRKGKTMSQVAINWCICK-GA-IPIPGVKTVRH 1060
                +   F++ L  +  L    K+   R GK++  +A+ W + + GA I + G +    
Sbjct: 230  DPKFQKPRFKEYLSAVNQLDKLAKT---RYGKSVIHLAVRWILDQPGADIALWGARKPGQ 286

Query: 1061 VEDNLGALGWRLS 1099
            +E      GW L+
Sbjct: 287  LEALSEITGWTLN 299
to top
>Q27955:KCAB2_BOVIN Voltage-gated potassium channel subunit beta-2 - Bos taurus (Bovine)|
          Length = 367

 Score = 96.3 bits (238), Expect = 3e-19
 Identities = 86/324 (26%), Positives = 157/324 (48%), Gaps = 20/324 (6%)
 Frame = +2

Query: 215  LSVSPMGFGTWA-WGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQS 391
            L VS +G GTW  +G Q+        D   ++   LA  NGINLFDTA+ Y  GK    +
Sbjct: 47   LRVSCLGLGTWVTFGGQIT-------DEMAEQLMTLAYDNGINLFDTAEVYAAGK----A 95

Query: 392  ERLLGKFIRECQGPIKSPDDVVIATKF-----AAYPWRLTSGQFVNACRSSLERLQIDRL 556
            E +LG  I++ +G  +S   +VI TK      A     L+    +   ++SLERLQ++ +
Sbjct: 96   EVVLGNIIKK-KGWRRS--SLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYV 152

Query: 557  GIGQLHWSTANYAPLQERALWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSYLASRG-VP 733
             +   +    N  P++E      +  + ++G+    G S +   ++++ +S       +P
Sbjct: 153  DVVFANRPDPN-TPMEETV--RAMTHVINQGMAMYWGTSRWSSMEIMEAYSVARQFNLIP 209

Query: 734  LSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGMLTGKYDASNLPNGPRSVLF 913
                Q ++ +    + +++L  +   +GV  + +SPL  G+++GKYD+   P    S+  
Sbjct: 210  PICEQAEYHMFQREKVEVQLPELFHKIGVGAMTWSPLACGIVSGKYDSGIPPYSRASLKG 269

Query: 914  RQILPG---------LESLLSCLKSIADRKGKTMSQVAINWCICKGAIP--IPGVKTVRH 1060
             Q L            ++ L  L++IA+R G T+ Q+AI WC+    +   + G  +   
Sbjct: 270  YQWLKDKILSEEGRRQQAKLKELQAIAERLGCTLPQLAIAWCLRNEGVSSVLLGASSADQ 329

Query: 1061 VEDNLGALGW--RLSPGEISELEA 1126
            + +N+GA+    +LS   I E+++
Sbjct: 330  LMENIGAIQVLPKLSSSIIHEIDS 353
to top
>P77735:YAJO_ECOLI Uncharacterized oxidoreductase yajO - Escherichia coli|
          Length = 324

 Score = 95.9 bits (237), Expect = 3e-19
 Identities = 92/318 (28%), Positives = 147/318 (46%), Gaps = 10/318 (3%)
 Frame = +2

Query: 200  VNVGPLSVSPMGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKL 379
            + V  L +  M FG    GN      EES    ++     AL+ GIN FDTA+SY     
Sbjct: 11   LRVSRLCLGCMTFGEPDRGNHAWTLPEESSRPIIKR----ALEGGINFFDTANSYS---- 62

Query: 380  NGQSERLLGKFIRECQGPIKSPDDVVIATK----FAAYPWRLTSGQFVNACRSSLERLQI 547
            +G SE ++G+ +R+        +DVV+ATK        P  L+  Q + +   SL RL +
Sbjct: 63   DGSSEEIVGRALRD----FARREDVVVATKVFHRVGDLPEGLSRAQILRSIDDSLRRLGM 118

Query: 548  DRLGIGQLHWSTANYAPLQERALWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSYLASRG 727
            D + I Q+H    N  P++E    + L ++   G  R +G S+    Q  +        G
Sbjct: 119  DYVDILQIHRWDYN-TPIEETL--EALNDVVKAGKARYIGASSMHASQFAQALELQKQHG 175

Query: 728  -VPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGMLT---GKYDASNLPNG 895
                 S Q  ++L+   EE+ E+  +C   GV +I +SPL  G LT   G+  A  + + 
Sbjct: 176  WAQFVSMQDHYNLI-YREEEREMLPLCYQEGVAVIPWSPLARGRLTRPWGETTARLVSDE 234

Query: 896  PRSVLFRQILPGLESLLSCLKSIADRKGKTMSQVAINWCICKGAI--PIPGVKTVRHVED 1069
                L+++       +   L  +++  G T +QVA+ W + K  I  PI G      +++
Sbjct: 235  VGKNLYKESDENDAQIAERLTGVSEELGATRAQVALAWLLSKPGIAAPIIGTSREEQLDE 294

Query: 1070 NLGALGWRLSPGEISELE 1123
             L A+   L P +I+ELE
Sbjct: 295  LLNAVDITLKPEQIAELE 312
to top
>P62483:KCAB2_RAT Voltage-gated potassium channel subunit beta-2 - Rattus norvegicus|
            (Rat)
          Length = 367

 Score = 95.5 bits (236), Expect = 4e-19
 Identities = 82/308 (26%), Positives = 147/308 (47%), Gaps = 18/308 (5%)
 Frame = +2

Query: 215  LSVSPMGFGTWA-WGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQS 391
            L VS +G GTW  +G Q+        D   +    LA  NGINLFDTA+ Y  GK    +
Sbjct: 47   LRVSCLGLGTWVTFGGQIT-------DEMAEHLMTLAYDNGINLFDTAEVYAAGK----A 95

Query: 392  ERLLGKFIRECQGPIKSPDDVVIATKF-----AAYPWRLTSGQFVNACRSSLERLQIDRL 556
            E +LG  I++ +G  +S   +VI TK      A     L+    +   ++SLERLQ++ +
Sbjct: 96   EVVLGNIIKK-KGWRRS--SLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYV 152

Query: 557  GIGQLHWSTANYAPLQERALWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSYLASRG-VP 733
             +   +    N  P++E      +  + ++G+    G S +   ++++ +S       +P
Sbjct: 153  DVVFANRPDPN-TPMEETVR--AMTHVINQGMAMYWGTSRWSSMEIMEAYSVARQFNLIP 209

Query: 734  LSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGMLTGKYDASNLPNGPRSVLF 913
                Q ++ +    + +++L  +   +GV  + +SPL  G+++GKYD+   P    S+  
Sbjct: 210  PICEQAEYHMFQREKVEVQLPELFHKIGVGAMTWSPLACGIVSGKYDSGIPPYSRASLKG 269

Query: 914  RQILPG---------LESLLSCLKSIADRKGKTMSQVAINWCICKGAIP--IPGVKTVRH 1060
             Q L            ++ L  L++IA+R G T+ Q+AI WC+    +   + G      
Sbjct: 270  YQWLKDKILSEEGRRQQAKLKELQAIAERLGCTLPQLAIAWCLRNEGVSSVLLGASNAEQ 329

Query: 1061 VEDNLGAL 1084
            + +N+GA+
Sbjct: 330  LMENIGAI 337
to top
>P62482:KCAB2_MOUSE Voltage-gated potassium channel subunit beta-2 - Mus musculus (Mouse)|
          Length = 367

 Score = 95.5 bits (236), Expect = 4e-19
 Identities = 82/308 (26%), Positives = 147/308 (47%), Gaps = 18/308 (5%)
 Frame = +2

Query: 215  LSVSPMGFGTWA-WGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQS 391
            L VS +G GTW  +G Q+        D   +    LA  NGINLFDTA+ Y  GK    +
Sbjct: 47   LRVSCLGLGTWVTFGGQIT-------DEMAEHLMTLAYDNGINLFDTAEVYAAGK----A 95

Query: 392  ERLLGKFIRECQGPIKSPDDVVIATKF-----AAYPWRLTSGQFVNACRSSLERLQIDRL 556
            E +LG  I++ +G  +S   +VI TK      A     L+    +   ++SLERLQ++ +
Sbjct: 96   EVVLGNIIKK-KGWRRS--SLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYV 152

Query: 557  GIGQLHWSTANYAPLQERALWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSYLASRG-VP 733
             +   +    N  P++E      +  + ++G+    G S +   ++++ +S       +P
Sbjct: 153  DVVFANRPDPN-TPMEETVR--AMTHVINQGMAMYWGTSRWSSMEIMEAYSVARQFNLIP 209

Query: 734  LSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGMLTGKYDASNLPNGPRSVLF 913
                Q ++ +    + +++L  +   +GV  + +SPL  G+++GKYD+   P    S+  
Sbjct: 210  PICEQAEYHMFQREKVEVQLPELFHKIGVGAMTWSPLACGIVSGKYDSGIPPYSRASLKG 269

Query: 914  RQILPG---------LESLLSCLKSIADRKGKTMSQVAINWCICKGAIP--IPGVKTVRH 1060
             Q L            ++ L  L++IA+R G T+ Q+AI WC+    +   + G      
Sbjct: 270  YQWLKDKILSEEGRRQQAKLKELQAIAERLGCTLPQLAIAWCLRNEGVSSVLLGASNAEQ 329

Query: 1061 VEDNLGAL 1084
            + +N+GA+
Sbjct: 330  LMENIGAI 337
to top
>Q13303:KCAB2_HUMAN Voltage-gated potassium channel subunit beta-2 - Homo sapiens (Human)|
          Length = 367

 Score = 95.1 bits (235), Expect = 6e-19
 Identities = 86/324 (26%), Positives = 156/324 (48%), Gaps = 20/324 (6%)
 Frame = +2

Query: 215  LSVSPMGFGTWA-WGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQS 391
            L VS +G GTW  +G Q+        D   ++   LA  NGINLFDTA+ Y  GK    +
Sbjct: 47   LRVSCLGLGTWVTFGGQIT-------DEMAEQLMTLAYDNGINLFDTAEVYAAGK----A 95

Query: 392  ERLLGKFIRECQGPIKSPDDVVIATKF-----AAYPWRLTSGQFVNACRSSLERLQIDRL 556
            E +LG  I++ +G  +S   +VI TK      A     L+    +   ++SLERLQ++ +
Sbjct: 96   EVVLGNIIKK-KGWRRS--SLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYV 152

Query: 557  GIGQLHWSTANYAPLQERALWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSYLASRGV-P 733
             +   +    N  P++E      +  + ++G+    G S +   ++++ +S      + P
Sbjct: 153  DVVFANRPDPN-TPMEETV--RAMTHVINQGMAMYWGTSRWSSMEIMEAYSVARQFNLTP 209

Query: 734  LSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGMLTGKYDASNLPNGPRSVLF 913
                Q ++ +    + +++L  +   +GV  + +SPL  G+++GKYD+   P    S+  
Sbjct: 210  PICEQAEYHMFQREKVEVQLPELFHKIGVGAMTWSPLACGIVSGKYDSGIPPYSRASLKG 269

Query: 914  RQILPG---------LESLLSCLKSIADRKGKTMSQVAINWCICKGAIP--IPGVKTVRH 1060
             Q L            ++ L  L++IA+R G T+ Q+AI WC+    +   + G      
Sbjct: 270  YQWLKDKILSEEGRRQQAKLKELQAIAERLGCTLPQLAIAWCLRNEGVSSVLLGASNADQ 329

Query: 1061 VEDNLGALGW--RLSPGEISELEA 1126
            + +N+GA+    +LS   I E+++
Sbjct: 330  LMENIGAIQVLPKLSSSIIHEIDS 353
to top
>Q9PTM5:KCAB2_XENLA Voltage-gated potassium channel subunit beta-2 - Xenopus laevis|
            (African clawed frog)
          Length = 367

 Score = 94.7 bits (234), Expect = 7e-19
 Identities = 82/308 (26%), Positives = 146/308 (47%), Gaps = 18/308 (5%)
 Frame = +2

Query: 215  LSVSPMGFGTWA-WGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQS 391
            L VS +G GTW  +G Q+        D   ++   LA  NGINLFDTA+ Y  GK    +
Sbjct: 47   LRVSCLGLGTWVTFGGQIT-------DEMAEQLMTLAYDNGINLFDTAEVYAAGK----A 95

Query: 392  ERLLGKFIRECQGPIKSPDDVVIATKF-----AAYPWRLTSGQFVNACRSSLERLQIDRL 556
            E +LG  I++ +G  +S   +VI TK      A     L+    +   ++SLERLQ+D +
Sbjct: 96   EVVLGNIIKK-KGWRRS--SLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLDYV 152

Query: 557  GIGQLHWSTANYAPLQERALWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSYLASRG-VP 733
             +   +    N  P++E      +  + ++G+    G S +   ++++ +S       +P
Sbjct: 153  DVVFANRPDPN-TPMEETV--RAMTHVINQGMAMYWGTSRWSSMEIMEAYSVARQFNLIP 209

Query: 734  LSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGMLTGKYDASNLPNGPRSVLF 913
                Q ++ +    + +++L  +   +GV  + +SPL  G+++GKYD    P    S+  
Sbjct: 210  PICEQAEYHMFQREKVEVQLPELFHKIGVGAMTWSPLACGIVSGKYDGGIPPYSRASLKG 269

Query: 914  RQILPG---------LESLLSCLKSIADRKGKTMSQVAINWCICKGAIP--IPGVKTVRH 1060
             Q L            ++ L   ++IA+R G T+ Q+AI WC+    +   + G      
Sbjct: 270  YQWLKDKILSEEGRRQQAKLKEFQAIAERLGCTLPQLAIAWCLRNEGVSSVLLGASNADQ 329

Query: 1061 VEDNLGAL 1084
            + +N+GA+
Sbjct: 330  LLENIGAI 337
to top
>P46905:YCCK_BACSU Uncharacterized oxidoreductase yccK - Bacillus subtilis|
          Length = 310

 Score = 94.0 bits (232), Expect = 1e-18
 Identities = 92/316 (29%), Positives = 150/316 (47%), Gaps = 16/316 (5%)
 Frame = +2

Query: 215  LSVSPMGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQSE 394
            L V  +GFG  A G   L  +    D   ++    AL  G+N  DTA  YG G+    SE
Sbjct: 12   LKVKRIGFGANAVGGHNL--FPNLNDETGKDLVRTALDGGVNFIDTAFIYGLGR----SE 65

Query: 395  RLLGKFIRECQGPIKSPDDVVIATKFAAYPWRLT-----SGQFVNA-CRSSLERLQIDRL 556
             L+G+ ++E +G     ++++IATK A      +     S +F+ +    SL+RL+ D +
Sbjct: 66   ELIGEVVQE-RGV---RNELIIATKGAHKEVDGSIELDNSREFLRSEVEKSLKRLKTDYI 121

Query: 557  GIGQLHWSTANYAPLQERALWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSYLASRGVPL 736
             +  +H+      PL E A    L E+ D+G ++A+G SN   +QL   ++        L
Sbjct: 122  DLYYVHFPDGK-TPLAEVA--GTLKELKDEGKIKAIGASNLDYQQLQDFNA-----DGYL 173

Query: 737  SSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGMLTGKYDASNLPNGPRSVLFR 916
               Q ++SL+    E+ EL   C+  G+  I Y PL  G+LTGK+    + +      FR
Sbjct: 174  EVFQAEYSLIQRDAEK-ELLPYCEKQGISFIPYFPLASGLLTGKFTQDTVFDD-----FR 227

Query: 917  QILPGLE--------SLLSCLKSIADRKGKTMSQVAINWCICKGAIP--IPGVKTVRHVE 1066
            +  P  +          +  LK++A+ K    + VA+ W + + AI   IPG K    ++
Sbjct: 228  KDKPQFQGETFIHNLKKVDKLKAVAEEKQADTAHVALAWLLTRPAIDAIIPGAKRPEQLQ 287

Query: 1067 DNLGALGWRLSPGEIS 1114
            DNL  L   L+  E++
Sbjct: 288  DNLKTLNIELTEDEVN 303
to top
>Q9PTM4:KCAB3_XENLA Voltage-gated potassium channel subunit beta-3 - Xenopus laevis|
            (African clawed frog)
          Length = 401

 Score = 94.0 bits (232), Expect = 1e-18
 Identities = 85/324 (26%), Positives = 152/324 (46%), Gaps = 21/324 (6%)
 Frame = +2

Query: 215  LSVSPMGFGTWA-WGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQS 391
            L VS +G GTW  +G+Q+        D   +    +A ++G+NLFDTA+ Y  G+    +
Sbjct: 81   LRVSCLGLGTWVTFGSQI-------SDEVAENLMTVAYEHGVNLFDTAEVYAAGR----A 129

Query: 392  ERLLGKFIRECQGPIKSPDDVVIATKF-----AAYPWRLTSGQFVNACRSSLERLQIDRL 556
            ER LGK +++ +    S    V+ TK      A     L+    +   R SLERLQ+D +
Sbjct: 130  ERTLGKILKKKEWRRSS---YVVTTKIYWGGQAETERGLSRKHIIEGLRGSLERLQLDYV 186

Query: 557  GIGQLHWSTANYAPLQERALWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSYLASRG-VP 733
             I   +    N +P++E  +   +  + ++G+    G S +   ++++ +S       +P
Sbjct: 187  DIVFANRMDPN-SPMEE--IVRAMTFVINQGMAMYWGTSRWSAMEIMEAYSVARQFNLIP 243

Query: 734  LSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGMLTGKYDASNLPNGPRSVL- 910
                Q ++ L    + + +L  +   +GV  + +SPL  G++TGKY    +P   R+   
Sbjct: 244  PVCEQAEYHLFQREKVETQLPELYHKIGVGSMTWSPLACGLITGKY-TDTVPEKSRASFK 302

Query: 911  ---------FRQILPGLESLLSCLKSIADRKGKTMSQVAINWCICKGAIP--IPGVKTVR 1057
                       Q      S +  L  IADR   T++Q+AI WC+    +   + GV  + 
Sbjct: 303  GYHWLKEKAISQEGKKQHSKVKELHPIADRLNCTVTQLAIAWCLRSEGVSSVLLGVSNIE 362

Query: 1058 HVEDNLGALGW--RLSPGEISELE 1123
             + +NLGA+     L+P  ++E++
Sbjct: 363  QLLENLGAIQVLPHLTPQLVTEID 386
to top
>O43448:KCAB3_HUMAN Voltage-gated potassium channel subunit beta-3 - Homo sapiens (Human)|
          Length = 404

 Score = 90.9 bits (224), Expect = 1e-17
 Identities = 86/324 (26%), Positives = 158/324 (48%), Gaps = 21/324 (6%)
 Frame = +2

Query: 215  LSVSPMGFGTWA-WGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQS 391
            L VS +G GTW  +G+Q+        D   ++   +A ++G+NLFDTA+ Y  GK    +
Sbjct: 88   LRVSCLGLGTWVTFGSQI-------SDETAEDVLTVAYEHGVNLFDTAEVYAAGK----A 136

Query: 392  ERLLGKFIRECQGPIKSPDDVVIATKF-----AAYPWRLTSGQFVNACRSSLERLQIDRL 556
            ER LG  ++  +G  +S    VI TK      A     L+    +   R SLERLQ+  +
Sbjct: 137  ERTLGNILKS-KGWRRS--SYVITTKIFWGGQAETERGLSRKHIIEGLRGSLERLQLGYV 193

Query: 557  GIGQLHWSTANYAPLQERALWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSYLASRG-VP 733
             I   + S  N  P++E  +   +  + ++GL    G S +G  ++++ +S       +P
Sbjct: 194  DIVFANRSDPN-CPMEE--IVRAMTYVINQGLALYWGTSRWGAAEIMEAYSMARQFNLIP 250

Query: 734  LSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGMLTGKYDASNLPNGPRSVL- 910
                Q +  L    + +M+L  +   +GV  + + PL  G++T KYD   +P+  R+ + 
Sbjct: 251  PVCEQAEHHLFQREKVEMQLPELYHKIGVGSVTWYPLACGLITSKYD-GRVPDTCRASIK 309

Query: 911  -FRQILPGLES--------LLSCLKSIADRKGKTMSQVAINWCICKGAIP--IPGVKTVR 1057
             ++ +   ++S         +  L  +A + G T++Q+AI WC+    +   + GV +  
Sbjct: 310  GYQWLKDKVQSEDGKKQQAKVMDLLPVAHQLGCTVAQLAIAWCLRSEGVSSVLLGVSSAE 369

Query: 1058 HVEDNLGALG--WRLSPGEISELE 1123
             + ++LGAL    +L+P  + E++
Sbjct: 370  QLIEHLGALQVLSQLTPQTVMEID 393
to top
>Q09923:YAKC_SCHPO Aldo-keto reductase yakc [NADP+] - Schizosaccharomyces pombe (Fission|
            yeast)
          Length = 340

 Score = 90.5 bits (223), Expect = 1e-17
 Identities = 86/330 (26%), Positives = 156/330 (47%), Gaps = 22/330 (6%)
 Frame = +2

Query: 206  VGPLSVSPMGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNG 385
            +G  +V  +GFG    G   ++G   S +   Q     A   G   +D++D YG G    
Sbjct: 8    IGNDTVPAIGFG--CMGLHAMYG--PSSEEANQAVLTHAADLGCTFWDSSDMYGFGA--- 60

Query: 386  QSERLLGKFIRECQGPIKSPDDVVIATKFAAYPWRLTSGQFV---------NACRSSLER 538
             +E  +G++ ++  G  K   ++ +ATKF  Y     +G+            A   SL+R
Sbjct: 61   -NEECIGRWFKQT-GRRK---EIFLATKFG-YEKNPETGELSLNNEPDYIEKALDLSLKR 114

Query: 539  LQIDRLGIGQLHWSTANYAPLQERALWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSYLA 718
            L ID + +  +H  +    P+++  +   L +  + G +R +G+S      + +     A
Sbjct: 115  LGIDCIDLYYVHRFSGE-TPIEK--IMGALKKCVEAGKIRYIGLSECSANTIRR-----A 166

Query: 719  SRGVPLSSAQVQFSLLSMGEEQMELKTV--CDSLGVRLIAYSPLGLGMLTGKYDA-SNLP 889
            +   P+S+ QV++S  S+  E+ E+  +  C    + ++ Y+PLG G LTG Y +  + P
Sbjct: 167  AAVYPVSAVQVEYSPFSLEIERPEIGVMKACRENNITIVCYAPLGRGFLTGAYKSPDDFP 226

Query: 890  NGPRSVLFRQILPGLES--------LLSCLKSIADRKGKTMSQVAINWCICKG--AIPIP 1039
             G     FR+  P  +         L++ ++ IA     T  Q+++ W + +G   +PIP
Sbjct: 227  EGD----FRRKAPRYQKENFYKNLELVTKIEKIATANNITPGQLSLAWLLAQGDDILPIP 282

Query: 1040 GVKTVRHVEDNLGALGWRLSPGEISELEAA 1129
            G K V+++E+N GAL  +LS   + E+  A
Sbjct: 283  GTKRVKYLEENFGALKVKLSDATVKEIREA 312
to top
>Q9XT31:KCAB1_RABIT Voltage-gated potassium channel subunit beta-1 - Oryctolagus|
            cuniculus (Rabbit)
          Length = 419

 Score = 90.5 bits (223), Expect = 1e-17
 Identities = 79/318 (24%), Positives = 153/318 (48%), Gaps = 19/318 (5%)
 Frame = +2

Query: 188  PWEKVNVGPLSVSPMGFGTWA-WGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSY 364
            P   +    L VS +G GTW  +G Q+        D   +    +A ++G+NLFDTA+ Y
Sbjct: 90   PHRNLGKSGLRVSCLGLGTWVTFGGQI-------SDEVAERLMTIAYESGVNLFDTAEVY 142

Query: 365  GTGKLNGQSERLLGKFIRECQGPIKSPDDVVIATKF-----AAYPWRLTSGQFVNACRSS 529
              GK    +E +LG  I++ +G  +S   +VI TK      A     L+    +   + S
Sbjct: 143  AAGK----AEVILGSIIKK-KGWRRS--SLVITTKLYWGGKAETERGLSRKHIIEGLKGS 195

Query: 530  LERLQIDRLGIGQLHWSTANYAPLQERALWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHS 709
            L+RLQ++ + +   +   +N  P++E  +   +  + ++G+    G S +   ++++ +S
Sbjct: 196  LQRLQLEYVDVVFANRPDSN-TPMEE--IVRAMTHVINQGMAMYWGTSRWSAMEIMEAYS 252

Query: 710  YLASRG-VPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGMLTGKYDASNL 886
                   +P    Q ++ L    + +++L  +   +GV  + +SPL  G+++GKY  + +
Sbjct: 253  VARQFNMIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKY-GNGV 311

Query: 887  PNGPRSVL--FRQILPGL--------ESLLSCLKSIADRKGKTMSQVAINWCICKGAIP- 1033
            P   R+ L  ++ +   +        ++ L  L  IA+R G T+ Q+A+ WC+    +  
Sbjct: 312  PESSRASLKCYQWLKERIVSEEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLRNEGVSS 371

Query: 1034 -IPGVKTVRHVEDNLGAL 1084
             + G  T   + +NLGA+
Sbjct: 372  VLLGSSTPEQLIENLGAI 389
to top
>Q14722:KCAB1_HUMAN Voltage-gated potassium channel subunit beta-1 - Homo sapiens (Human)|
          Length = 419

 Score = 90.5 bits (223), Expect = 1e-17
 Identities = 79/318 (24%), Positives = 153/318 (48%), Gaps = 19/318 (5%)
 Frame = +2

Query: 188  PWEKVNVGPLSVSPMGFGTWA-WGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSY 364
            P   +    L VS +G GTW  +G Q+        D   +    +A ++G+NLFDTA+ Y
Sbjct: 90   PHRNLGKSGLRVSCLGLGTWVTFGGQI-------SDEVAERLMTIAYESGVNLFDTAEVY 142

Query: 365  GTGKLNGQSERLLGKFIRECQGPIKSPDDVVIATKF-----AAYPWRLTSGQFVNACRSS 529
              GK    +E +LG  I++ +G  +S   +VI TK      A     L+    +   + S
Sbjct: 143  AAGK----AEVILGSIIKK-KGWRRS--SLVITTKLYWGGKAETERGLSRKHIIEGLKGS 195

Query: 530  LERLQIDRLGIGQLHWSTANYAPLQERALWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHS 709
            L+RLQ++ + +   +   +N  P++E  +   +  + ++G+    G S +   ++++ +S
Sbjct: 196  LQRLQLEYVDVVFANRPDSN-TPMEE--IVRAMTHVINQGMAMYWGTSRWSAMEIMEAYS 252

Query: 710  YLASRG-VPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGMLTGKYDASNL 886
                   +P    Q ++ L    + +++L  +   +GV  + +SPL  G+++GKY  + +
Sbjct: 253  VARQFNMIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKY-GNGV 311

Query: 887  PNGPRSVL--FRQILPGL--------ESLLSCLKSIADRKGKTMSQVAINWCICKGAIP- 1033
            P   R+ L  ++ +   +        ++ L  L  IA+R G T+ Q+A+ WC+    +  
Sbjct: 312  PESSRASLKCYQWLKERIVSEEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLRNEGVSS 371

Query: 1034 -IPGVKTVRHVEDNLGAL 1084
             + G  T   + +NLGA+
Sbjct: 372  VLLGSSTPEQLIENLGAI 389
to top
>Q40648:KCAB_ORYSJ Probable voltage-gated potassium channel subunit beta - Oryza sativa|
            subsp. japonica (Rice)
          Length = 328

 Score = 89.7 bits (221), Expect = 2e-17
 Identities = 95/334 (28%), Positives = 158/334 (47%), Gaps = 22/334 (6%)
 Frame = +2

Query: 215  LSVSPMGFGTWA-WGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQS 391
            L VS + +G W  +GNQL     +++   LQ C +     G+N FD A+ Y     NG++
Sbjct: 11   LRVSQLSYGAWVTFGNQLDVKEAKAL---LQACRDA----GVNFFDNAEVYA----NGRA 59

Query: 392  ERLLGKFIRECQGPIKSPDDVVIATKF-----AAYPWRLTSGQFVNACRSSLERLQIDRL 556
            E ++G+ +R+  G  +S  DVV++TK            L+    V   R SL+RL +D +
Sbjct: 60   EEIMGQAMRDL-GWRRS--DVVVSTKLFWGGQGPNDKGLSRKHIVEGLRGSLKRLDMDYV 116

Query: 557  GIGQLHWSTANYAPLQE--RAL-WDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSYLASRG 727
             +   H   A   P++E  RA+ W     + D G+    G S +  +Q+ +  S +A+R 
Sbjct: 117  DVVYCHRPDAT-TPVEETVRAMNW-----VIDHGMAFYWGTSEWSAQQITEAWS-VANRL 169

Query: 728  --VPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGMLTGKYDASNLPNGPR 901
              V     Q +++L S  + + E   +  + G+ L  +SPL  G+LTGKY   N+P   R
Sbjct: 170  DLVGPIVEQPEYNLFSRHKVESEFLPLYSTYGLGLTTWSPLASGVLTGKYAKGNIPADSR 229

Query: 902  SVL-------FRQILPGLESLLSCLKSIADRKGKTMSQVAINWCICKGAIP--IPGVKTV 1054
              L        R ++      ++ LK IA   G +++Q+AI WC     +   I G    
Sbjct: 230  FALENYKNLANRSLVDDTLRKVNGLKPIASELGVSLAQLAIAWCASNPNVSSVITGATKE 289

Query: 1055 RHVEDNLGALGW--RLSPGEISELEAAAMECPKK 1150
              + +N+ AL     L+P  + ++EA     PK+
Sbjct: 290  NQIVENMKALDVIPLLTPEVVDKIEAVVQSKPKR 323
to top
>P63144:KCAB1_RAT Voltage-gated potassium channel subunit beta-1 - Rattus norvegicus|
            (Rat)
          Length = 401

 Score = 89.7 bits (221), Expect = 2e-17
 Identities = 78/309 (25%), Positives = 151/309 (48%), Gaps = 19/309 (6%)
 Frame = +2

Query: 215  LSVSPMGFGTWA-WGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQS 391
            L VS +G GTW  +G Q+        D   +    +A ++G+NLFDTA+ Y  GK    +
Sbjct: 81   LRVSCLGLGTWVTFGGQI-------SDEVAERLMTIAYESGVNLFDTAEVYAAGK----A 129

Query: 392  ERLLGKFIRECQGPIKSPDDVVIATKF-----AAYPWRLTSGQFVNACRSSLERLQIDRL 556
            E +LG  I++ +G  +S   +VI TK      A     L+    +   + SL+RLQ++ +
Sbjct: 130  EVILGSIIKK-KGWRRS--SLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYV 186

Query: 557  GIGQLHWSTANYAPLQERALWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSYLASRG-VP 733
             +   +   +N  P++E  +   +  + ++G+    G S +   ++++ +S       +P
Sbjct: 187  DVVFANRPDSN-TPMEE--IVRAMTHVINQGMAMYWGTSRWSAMEIMEAYSVARQFNMIP 243

Query: 734  LSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGMLTGKYDASNLPNGPRSVL- 910
                Q ++ L    + +++L  +   +GV  + +SPL  G+++GKY  + +P   R+ L 
Sbjct: 244  PVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKY-GNGVPESSRASLK 302

Query: 911  -FRQILPGL--------ESLLSCLKSIADRKGKTMSQVAINWCICKGAIP--IPGVKTVR 1057
             ++ +   +        ++ L  L  IA+R G T+ Q+A+ WC+    +   + G  T  
Sbjct: 303  CYQWLKERIVSEEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLRNEGVSSVLLGSSTPE 362

Query: 1058 HVEDNLGAL 1084
             + +NLGA+
Sbjct: 363  QLIENLGAI 371
to top
>Q28528:KCAB1_MUSPU Voltage-gated potassium channel subunit beta-1 - Mustela putorius|
            (European polecat)
          Length = 408

 Score = 89.7 bits (221), Expect = 2e-17
 Identities = 78/309 (25%), Positives = 151/309 (48%), Gaps = 19/309 (6%)
 Frame = +2

Query: 215  LSVSPMGFGTWA-WGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQS 391
            L VS +G GTW  +G Q+        D   +    +A ++G+NLFDTA+ Y  GK    +
Sbjct: 88   LRVSCLGLGTWVTFGGQI-------SDEVAERLMTIAYESGVNLFDTAEVYAAGK----A 136

Query: 392  ERLLGKFIRECQGPIKSPDDVVIATKF-----AAYPWRLTSGQFVNACRSSLERLQIDRL 556
            E +LG  I++ +G  +S   +VI TK      A     L+    +   + SL+RLQ++ +
Sbjct: 137  EVILGSIIKK-KGWRRS--SLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYV 193

Query: 557  GIGQLHWSTANYAPLQERALWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSYLASRG-VP 733
             +   +   +N  P++E  +   +  + ++G+    G S +   ++++ +S       +P
Sbjct: 194  DVVFANRPDSN-TPMEE--IVRAMTHVINQGMAMYWGTSRWSAMEIMEAYSVARQFNMIP 250

Query: 734  LSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGMLTGKYDASNLPNGPRSVL- 910
                Q ++ L    + +++L  +   +GV  + +SPL  G+++GKY  + +P   R+ L 
Sbjct: 251  PVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKY-GNGVPESSRASLK 309

Query: 911  -FRQILPGL--------ESLLSCLKSIADRKGKTMSQVAINWCICKGAIP--IPGVKTVR 1057
             ++ +   +        ++ L  L  IA+R G T+ Q+A+ WC+    +   + G  T  
Sbjct: 310  CYQWLKERIVSEEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLRNEGVSSVLLGSSTPE 369

Query: 1058 HVEDNLGAL 1084
             + +NLGA+
Sbjct: 370  QLIENLGAI 378
to top
>P63143:KCAB1_MOUSE Voltage-gated potassium channel subunit beta-1 - Mus musculus (Mouse)|
          Length = 401

 Score = 89.7 bits (221), Expect = 2e-17
 Identities = 78/309 (25%), Positives = 151/309 (48%), Gaps = 19/309 (6%)
 Frame = +2

Query: 215  LSVSPMGFGTWA-WGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQS 391
            L VS +G GTW  +G Q+        D   +    +A ++G+NLFDTA+ Y  GK    +
Sbjct: 81   LRVSCLGLGTWVTFGGQI-------SDEVAERLMTIAYESGVNLFDTAEVYAAGK----A 129

Query: 392  ERLLGKFIRECQGPIKSPDDVVIATKF-----AAYPWRLTSGQFVNACRSSLERLQIDRL 556
            E +LG  I++ +G  +S   +VI TK      A     L+    +   + SL+RLQ++ +
Sbjct: 130  EVILGSIIKK-KGWRRS--SLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYV 186

Query: 557  GIGQLHWSTANYAPLQERALWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSYLASRG-VP 733
             +   +   +N  P++E  +   +  + ++G+    G S +   ++++ +S       +P
Sbjct: 187  DVVFANRPDSN-TPMEE--IVRAMTHVINQGMAMYWGTSRWSAMEIMEAYSVARQFNMIP 243

Query: 734  LSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGMLTGKYDASNLPNGPRSVL- 910
                Q ++ L    + +++L  +   +GV  + +SPL  G+++GKY  + +P   R+ L 
Sbjct: 244  PVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKY-GNGVPESSRASLK 302

Query: 911  -FRQILPGL--------ESLLSCLKSIADRKGKTMSQVAINWCICKGAIP--IPGVKTVR 1057
             ++ +   +        ++ L  L  IA+R G T+ Q+A+ WC+    +   + G  T  
Sbjct: 303  CYQWLKERIVSEEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLRNEGVSSVLLGSSTPE 362

Query: 1058 HVEDNLGAL 1084
             + +NLGA+
Sbjct: 363  QLIENLGAI 371
to top
>Q4PJK1:KCAB1_BOVIN Voltage-gated potassium channel subunit beta-1 - Bos taurus (Bovine)|
          Length = 401

 Score = 89.7 bits (221), Expect = 2e-17
 Identities = 78/309 (25%), Positives = 151/309 (48%), Gaps = 19/309 (6%)
 Frame = +2

Query: 215  LSVSPMGFGTWA-WGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQS 391
            L VS +G GTW  +G Q+        D   +    +A ++G+NLFDTA+ Y  GK    +
Sbjct: 81   LRVSCLGLGTWVTFGGQI-------SDEVAERLMTIAYESGVNLFDTAEVYAAGK----A 129

Query: 392  ERLLGKFIRECQGPIKSPDDVVIATKF-----AAYPWRLTSGQFVNACRSSLERLQIDRL 556
            E +LG  I++ +G  +S   +VI TK      A     L+    +   + SL+RLQ++ +
Sbjct: 130  EVILGSIIKK-KGWRRS--SLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYV 186

Query: 557  GIGQLHWSTANYAPLQERALWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSYLASRG-VP 733
             +   +   +N  P++E  +   +  + ++G+    G S +   ++++ +S       +P
Sbjct: 187  DVVFANRPDSN-TPMEE--IVRAMTHVINQGMAMYWGTSRWSAMEIMEAYSVARQFNMIP 243

Query: 734  LSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGMLTGKYDASNLPNGPRSVL- 910
                Q ++ L    + +++L  +   +GV  + +SPL  G+++GKY  + +P   R+ L 
Sbjct: 244  PVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKY-GNGVPESSRASLK 302

Query: 911  -FRQILPGL--------ESLLSCLKSIADRKGKTMSQVAINWCICKGAIP--IPGVKTVR 1057
             ++ +   +        ++ L  L  IA+R G T+ Q+A+ WC+    +   + G  T  
Sbjct: 303  CYQWLKERIVSEEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLRNEGVSSVLLGSSTPE 362

Query: 1058 HVEDNLGAL 1084
             + +NLGA+
Sbjct: 363  QLIENLGAI 371
to top
>Q9PWR1:KCAB1_CHICK Voltage-gated potassium channel subunit beta-1 - Gallus gallus|
            (Chicken)
          Length = 401

 Score = 89.4 bits (220), Expect = 3e-17
 Identities = 77/309 (24%), Positives = 151/309 (48%), Gaps = 19/309 (6%)
 Frame = +2

Query: 215  LSVSPMGFGTWA-WGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQS 391
            L VS +G GTW  +G Q+        D   ++   +A ++G+NLFDTA+ Y  GK    +
Sbjct: 81   LRVSCLGLGTWVTFGGQI-------SDEVAEQLMTIAYESGVNLFDTAEVYAAGK----A 129

Query: 392  ERLLGKFIRECQGPIKSPDDVVIATKF-----AAYPWRLTSGQFVNACRSSLERLQIDRL 556
            E +LG  +++ +G  +S   +VI TK      A     L+    +   R+SL+RLQ++ +
Sbjct: 130  EVILGNILKK-KGWRRS--SLVITTKLYWGGKAETERGLSRKHIIEGLRASLQRLQLEYV 186

Query: 557  GIGQLHWSTANYAPLQERALWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSYLASRG-VP 733
             +   +    N  P++E  +   +  + ++G+    G S +   ++++ +S       +P
Sbjct: 187  DVVFAN-RPDNNTPMEE--IVRAMTHVINQGMAMYWGTSRWSAMEIMEAYSVARQFNLIP 243

Query: 734  LSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGMLTGKYDASNLPNGPRSVL- 910
                Q ++ L    + +++L  +   +GV  + +SPL  G+++GKY  + +P   R+ L 
Sbjct: 244  PVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKY-GNGVPESSRAALK 302

Query: 911  -FRQILPGL--------ESLLSCLKSIADRKGKTMSQVAINWCICKGAIP--IPGVKTVR 1057
             ++ +   +        ++ L  L  IA+R G T+ Q+A+ WC+    +   + G     
Sbjct: 303  CYQWLKEKIISEEGRKQQTKLKDLSPIAERLGCTLPQLAVAWCLRNEGVSSVLLGSSNPE 362

Query: 1058 HVEDNLGAL 1084
             + +NLGA+
Sbjct: 363  QLIENLGAI 371
to top
>Q7G764:NADO1_ORYSJ Probable NAD(P)H-dependent oxidoreductase 1 - Oryza sativa subsp.|
            japonica (Rice)
          Length = 321

 Score = 85.9 bits (211), Expect = 3e-16
 Identities = 78/279 (27%), Positives = 125/279 (44%), Gaps = 16/279 (5%)
 Frame = +2

Query: 320  ALKNGINLFDTADSYGTGKLNGQSERLLGKFIREC--QGPIKSPDDVVIATKFAAYPWRL 493
            A++ G   FDTA  Y T       E  +G+ + E   +G I S  DV + +K       L
Sbjct: 41   AIELGYRHFDTARIYAT-------EGCVGEAVAEAVRRGLIASRADVFVTSKIWCSD--L 91

Query: 494  TSGQFVNACRSSLERLQIDRLGIGQLHWSTA----NY----------APLQERALWDGLV 631
             +G+ V A R +L  L +D + +  +HW  +    NY                 +W G+ 
Sbjct: 92   HAGRVVPAARETLRNLGMDYVDLLLVHWPVSLTPGNYDFPFPKEVILPSFDMEGVWRGME 151

Query: 632  EMYDKGLVRAVGVSNYGPKQLLKIHSYLASRGVPLSSAQVQFSLLSMGEEQMELKTVCDS 811
            E +  GL RA+GVSN+  K+L ++ S  A R    +  QV+ + +    +Q  L+ VC  
Sbjct: 152  ECHRLGLARAIGVSNFSAKKLEQLLSLAAVRP---AVNQVEVNPMW---QQRTLREVCRR 205

Query: 812  LGVRLIAYSPLGLGMLTGKYDASNLPNGPRSVLFRQILPGLESLLSCLKSIADRKGKTMS 991
             GV+L  YSPLG         A   P G  +V+   +L          + IA  KGKT++
Sbjct: 206  EGVQLCGYSPLG---------AKGTPWGSAAVMDSGVL----------QEIAGAKGKTLA 246

Query: 992  QVAINWCICKGAIPIPGVKTVRHVEDNLGALGWRLSPGE 1108
            Q+ + W   +G + +      + +++NL    W L+  E
Sbjct: 247  QICLRWLYEQGDVLLVKTYNEKRMKENLDIFNWELTDEE 285
to top
>Q63494:KCAB3_RAT Voltage-gated potassium channel subunit beta-3 - Rattus norvegicus|
            (Rat)
          Length = 404

 Score = 85.5 bits (210), Expect = 4e-16
 Identities = 81/325 (24%), Positives = 160/325 (49%), Gaps = 21/325 (6%)
 Frame = +2

Query: 215  LSVSPMGFGTWA-WGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQS 391
            L VS +G GTW  +G+Q+        D   ++   +A ++G+NLFDTA+ Y  GK    +
Sbjct: 88   LRVSCLGLGTWVTFGSQI-------SDETAEDLLTVAYEHGVNLFDTAEVYAAGK----A 136

Query: 392  ERLLGKFIRECQGPIKSPDDVVIATKF-----AAYPWRLTSGQFVNACRSSLERLQIDRL 556
            ER LG  ++  +G  +S    VI TK      A     L+    +   + SL+RLQ++ +
Sbjct: 137  ERTLGNILKS-KGWRRS--SYVITTKIFWGGQAETERGLSRKHIIEGLQGSLDRLQLEYV 193

Query: 557  GIGQLHWSTANYAPLQERALWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSYLASRG-VP 733
             I   + S  + +P++E  +   +  + ++GL    G S +   ++++ +S       +P
Sbjct: 194  DIVFANRSDPS-SPMEE--IVRAMTYVINQGLALYWGTSRWSAAEIMEAYSMARQFNLIP 250

Query: 734  LSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGMLTGKYDASNLPNGPRSVL- 910
                Q +       + +M+L  +   +GV  + +SPL   ++T KYD   +P+  ++ + 
Sbjct: 251  PVCEQAENHFFQREKVEMQLPELYHKIGVGSVTWSPLACSLITSKYD-GQVPDACKATVK 309

Query: 911  -FRQILPGLES--------LLSCLKSIADRKGKTMSQVAINWCICKGAIP--IPGVKTVR 1057
             ++ +   ++S         ++ L  IA + G T++Q+AI WC+    +   + GV +  
Sbjct: 310  GYQWLKEKVQSEDGKKQQARVTDLLPIAHQLGCTVAQLAIAWCLRSEGVSSVLLGVSSAE 369

Query: 1058 HVEDNLGALG--WRLSPGEISELEA 1126
             + ++LG+L    +L+P  + E++A
Sbjct: 370  QLMEHLGSLQVLGQLTPQTVMEIDA 394
to top
>Q46851:YGHZ_ECOLI Uncharacterized protein yghZ - Escherichia coli|
          Length = 346

 Score = 84.7 bits (208), Expect = 8e-16
 Identities = 76/285 (26%), Positives = 137/285 (48%), Gaps = 17/285 (5%)
 Frame = +2

Query: 281  ESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQSERLLGKFIRECQGPIKSPDDVVI 460
            ES  + L++ F+L    GI  FD A++YG     G +E   G+ +RE     +  D+++I
Sbjct: 43   ESQRAILRKAFDL----GITHFDLANNYGPPP--GSAEENFGRLLREDFAAYR--DELII 94

Query: 461  ATK--FAAYPWRLTSG----QFVNACRSSLERLQIDRLGIGQLHWSTANYAPLQERALWD 622
            +TK  +  +P    SG      + +   SL+R+ ++ + I   H    N  P++E A   
Sbjct: 95   STKAGYDMWPGPYGSGGSRKYLLASLDQSLKRMGLEYVDIFYSHRVDEN-TPMEETA--S 151

Query: 623  GLVEMYDKGLVRAVGVSNYGPKQLLKIHSYLASRGVPLSSAQVQFSLLSMGEEQMELKTV 802
             L      G    VG+S+Y P++  K+   L    +PL   Q  ++LL+   ++  L   
Sbjct: 152  ALAHAVQSGKALYVGISSYSPERTQKMVELLREWKIPLLIHQPSYNLLNRWVDKSGLLDT 211

Query: 803  CDSLGVRLIAYSPLGLGMLTGKYDASNLP---------NGPRSVLFRQILPGLESLLSCL 955
              + GV  IA++PL  G+LTGKY  + +P         N  R +  + +     + L  L
Sbjct: 212  LQNNGVGCIAFTPLAQGLLTGKY-LNGIPQDSRMHREGNKVRGLTPKMLTEANLNSLRLL 270

Query: 956  KSIADRKGKTMSQVAINWCICKGAIP--IPGVKTVRHVEDNLGAL 1084
              +A ++G++M+Q+A++W +    +   + G      +E+N+ AL
Sbjct: 271  NEMAQQRGQSMAQMALSWLLKDDRVTSVLIGASRAEQLEENVQAL 315
to top
>Q7G765:NADO2_ORYSJ Probable NAD(P)H-dependent oxidoreductase 2 - Oryza sativa subsp.|
            japonica (Rice)
          Length = 322

 Score = 84.7 bits (208), Expect = 8e-16
 Identities = 77/277 (27%), Positives = 127/277 (45%), Gaps = 14/277 (5%)
 Frame = +2

Query: 320  ALKNGINLFDTADSYGTGKLNGQSERLLGKFIRECQGPIKSPDDVVIATKFAAYPWRLTS 499
            A++ G   FDTA  Y T    G     + + +R  +G + S  DV + +K       L +
Sbjct: 43   AIELGYRHFDTARLYAT---EGCVSEAVAEAVR--RGLVASRADVFVTSKLWCSD--LHA 95

Query: 500  GQFVNACRSSLERLQIDRLGIGQLHW----STANYA---PLQERA-------LWDGLVEM 637
            G+ V A R +L  L +D + +  +HW    +  +Y    P +E A       +W G+ E 
Sbjct: 96   GRVVPAARETLRNLGMDYVDLLLVHWPATVAPGSYDFPFPKEEMAPAFDMEGVWRGMEEC 155

Query: 638  YDKGLVRAVGVSNYGPKQLLKIHSYLASRGVPLSSAQVQFSLLSMGEEQMELKTVCDSLG 817
            +  GL RA+GVSN+  K+L ++ S+   R    ++ QV+ + +    +Q  L+ VC   G
Sbjct: 156  HRLGLARAIGVSNFSAKKLEQLLSFAVVRP---AANQVEMNPM---WQQRTLREVCRREG 209

Query: 818  VRLIAYSPLGLGMLTGKYDASNLPNGPRSVLFRQILPGLESLLSCLKSIADRKGKTMSQV 997
            V+L  YSPLG         A   P G  +V+   +          L  IA  KGKT++Q+
Sbjct: 210  VQLCGYSPLG---------AKGTPWGSAAVMDSGV----------LHDIAQTKGKTLAQI 250

Query: 998  AINWCICKGAIPIPGVKTVRHVEDNLGALGWRLSPGE 1108
             + W   +G + +        +++NL    W L+  E
Sbjct: 251  CLRWMYEQGDVLLVKTYNENRMKENLDIFDWELTEEE 287
to top
>Q8X529:YGHZ_ECO57 Uncharacterized protein yghZ - Escherichia coli O157:H7|
          Length = 346

 Score = 84.3 bits (207), Expect = 1e-15
 Identities = 76/285 (26%), Positives = 137/285 (48%), Gaps = 17/285 (5%)
 Frame = +2

Query: 281  ESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQSERLLGKFIRECQGPIKSPDDVVI 460
            ES  + L++ F+L    GI  FD A++YG     G +E   G+ +RE     +  D+++I
Sbjct: 43   ESQRAILRKAFDL----GITHFDLANNYGPPP--GSAEENFGRLLREDFAAYR--DELII 94

Query: 461  ATK--FAAYPWRLTSG----QFVNACRSSLERLQIDRLGIGQLHWSTANYAPLQERALWD 622
            +TK  +  +P    SG      + +   SL+R+ ++ + I   H    N  P++E A   
Sbjct: 95   STKAGYDMWPGPYGSGGSRKYLLASLDQSLKRMGLEYVDIFYSHRVDEN-TPMEETA--S 151

Query: 623  GLVEMYDKGLVRAVGVSNYGPKQLLKIHSYLASRGVPLSSAQVQFSLLSMGEEQMELKTV 802
             L      G    VG+S+Y P++  K+   L    +PL   Q  ++LL+   ++  L   
Sbjct: 152  ALAHAVQSGKALYVGISSYSPERTQKMVELLHEWKIPLLIHQPSYNLLNRWVDKSGLLDT 211

Query: 803  CDSLGVRLIAYSPLGLGMLTGKYDASNLP---------NGPRSVLFRQILPGLESLLSCL 955
              + GV  IA++PL  G+LTGKY  + +P         N  R +  + +     + L  L
Sbjct: 212  LQNNGVGCIAFTPLAQGLLTGKY-LNGIPEDSRMHREGNKVRGLTPKMLTEANLNSLRLL 270

Query: 956  KSIADRKGKTMSQVAINWCICKGAIP--IPGVKTVRHVEDNLGAL 1084
              +A ++G++M+Q+A++W +    +   + G      +E+N+ AL
Sbjct: 271  NEMAQQRGQSMAQMALSWLLKDERVTSVLVGASRAEQLEENVQAL 315
to top
>P46336:IOLS_BACSU Protein iolS - Bacillus subtilis|
          Length = 310

 Score = 84.0 bits (206), Expect = 1e-15
 Identities = 89/329 (27%), Positives = 146/329 (44%), Gaps = 20/329 (6%)
 Frame = +2

Query: 197  KVNVGPLSVSPMGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGK 376
            K+    L V P+G GT A G   L  Y    +   +E    A++NG+ + DTA  YG G+
Sbjct: 5    KLGKSDLQVFPIGLGTNAVGGHNL--YPNLNEETGKELVREAIRNGVTMLDTAYIYGIGR 62

Query: 377  LNGQSERLLGKFIRECQGPIKSPDDVVIATKFAAYPWRLTSGQFV---------NACRSS 529
                SE L+G+ +RE      + +DVVIATK A    R     FV          +   S
Sbjct: 63   ----SEELIGEVLREF-----NREDVVIATKAA---HRKQGNDFVFDNSPDFLKKSVDES 110

Query: 530  LERLQIDRLGIGQLHWSTANYAPLQERALWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHS 709
            L+RL  D + +  +H+    + P  E    + L EM   G +R++GVSN+  +QL +   
Sbjct: 111  LKRLNTDYIDLFYIHFPD-EHTPKDEAV--NALNEMKKAGKIRSIGVSNFSLEQLKE--- 164

Query: 710  YLASRGVPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGMLTGKY-DASNL 886
              A++   +   Q +++LL+  E +           +  I Y PL  G+L GKY + +  
Sbjct: 165  --ANKDGLVDVLQGEYNLLNR-EAEKTFFPYTKEHNISFIPYFPLVSGLLAGKYTEDTTF 221

Query: 887  PNGP--------RSVLFRQILPGLESLLSCLKSIADRKGKTMSQVAINWCICKGAIP--I 1036
            P G         +   F++ +  +      L  IA++    +  + + W + +  I   I
Sbjct: 222  PEGDLRNEQEHFKGERFKENIRKVNK----LAPIAEKHNVDIPHIVLAWYLARPEIDILI 277

Query: 1037 PGVKTVRHVEDNLGALGWRLSPGEISELE 1123
            PG K    + DN+      LS  +IS ++
Sbjct: 278  PGAKRADQLIDNIKTADVTLSQEDISFID 306
to top
>O14295:PLR1_SCHPO Pyridoxal reductase - Schizosaccharomyces pombe (Fission yeast)|
          Length = 333

 Score = 83.6 bits (205), Expect = 2e-15
 Identities = 80/327 (24%), Positives = 136/327 (41%), Gaps = 14/327 (4%)
 Frame = +2

Query: 206  VGPLSVSPMGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNG 385
            V    V P+GFG       L W  +++ D E  E  N AL  G N +D  + YG      
Sbjct: 4    VSGFKVGPIGFGLMG----LTWKPKQTPDEEAFEVMNYALSQGSNYWDAGEFYGVDPPTS 59

Query: 386  QSERLLGKFIRECQGPIKSPDDVVIATKFAAYPWRLTSGQFVNACRSSLERLQIDRLGIG 565
              + LL ++  +     ++ + V ++ K       L      +    S+E +     G  
Sbjct: 60   NLD-LLARYFEKYP---ENANKVFLSVKGGLDFKTLVPDGNPDFVSKSVENVIAHLRGTK 115

Query: 566  QLH-WSTANYAP-LQERALWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSYLASRGVPLS 739
            +L  +  A   P +        L    D G +  VG+S    + + + H+      VP++
Sbjct: 116  KLDLFQCARVDPNVPIETTMKTLKGFVDSGKISCVGLSEVSAETIKRAHAV-----VPIA 170

Query: 740  SAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGMLTGKY-DASNLPNGPRSVLFR 916
            + +V++SL S   E   +  +C  L + +IAYSP   G+LTG+     +L    +S  F 
Sbjct: 171  AVEVEYSLFSRDIETNGIMDICRKLSIPIIAYSPFCRGLLTGRIKTVEDLKEFAKSFPFL 230

Query: 917  QILPGLE--------SLLSCLKSIADRKGKTMSQVAINWCICKG---AIPIPGVKTVRHV 1063
            + L              L  ++ +A + G TM + ++ + +  G    IPIPG  +V   
Sbjct: 231  EYLDRFSPDVFAKNLPFLQAVEQLAKKFGMTMPEFSLLFIMASGNGLVIPIPGSTSVSRT 290

Query: 1064 EDNLGALGWRLSPGEISELEAAAMECP 1144
            + NL AL   LSP +  E +    + P
Sbjct: 291  KSNLNALNKSLSPEQFKEAKEVLSKYP 317
to top
>P76234:YEAE_ECOLI Uncharacterized protein yeaE - Escherichia coli|
          Length = 284

 Score = 82.0 bits (201), Expect = 5e-15
 Identities = 82/308 (26%), Positives = 136/308 (44%), Gaps = 1/308 (0%)
 Frame = +2

Query: 209  GPLSVSPMGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQ 388
            G +S+  +G GTW  G       + S            ++ G+ L DTA+ Y     +G 
Sbjct: 10   GDVSLPAVGQGTWYMGE------DASQRKTEVAALRAGIELGLTLIDTAEMYA----DGG 59

Query: 389  SERLLGKFIRECQGPIKSPDDVVIATKFAAYPWRLTSGQFVNACRSSLERLQIDRLGIGQ 568
            +E+++G+ +   +      + V + +K   YPW     + +NAC +SL RL  D L +  
Sbjct: 60   AEKVVGEALTGLR------EKVFLVSK--VYPWNAGGQKAINACEASLRRLNTDYLDLYL 111

Query: 569  LHWSTANYAPLQERALWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSYLASRGVPLSSAQ 748
            LHWS  ++A  +  A  + L+    +G +R  GVSN     + ++  +    G   ++ Q
Sbjct: 112  LHWS-GSFAFEETVAAMEKLIA---QGKIRRWGVSNLDYADMQEL--WQLPGGNQCATNQ 165

Query: 749  VQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGMLTGKYDASNLPNGPRSVLFRQILP 928
            V + L S G E  +L   C    + ++AYSPL          A  L NG    L +    
Sbjct: 166  VLYHLGSRGIE-YDLLPWCQQQQMPVMAYSPLA--------QAGRLRNG----LLKN--- 209

Query: 929  GLESLLSCLKSIADRKGKTMSQVAINWCIC-KGAIPIPGVKTVRHVEDNLGALGWRLSPG 1105
                  + +  IA     + +QV + W I  +G + IP   T+ HV+ N   L   LS  
Sbjct: 210  ------AVVNEIAHAHNISAAQVLLAWVISHQGVMAIPKAATIAHVQQNAAVLEVELSSA 263

Query: 1106 EISELEAA 1129
            E++ L+ A
Sbjct: 264  ELAMLDKA 271
to top
>P0A9T5:TAS_SHIFL Protein tas - Shigella flexneri|
          Length = 346

 Score = 82.0 bits (201), Expect = 5e-15
 Identities = 92/347 (26%), Positives = 151/347 (43%), Gaps = 35/347 (10%)
 Frame = +2

Query: 191  WEKVNVGPLSVSPMGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGT 370
            + ++    L VS +G GT  +G       E++ +++     + A+  GINL D A+ Y  
Sbjct: 3    YHRIPHSSLEVSTLGLGTMTFG-------EQNSEADAHAQLDYAVAQGINLIDVAEMYPV 55

Query: 371  G---KLNGQSERLLGKFIRECQGPIKSPDDVVIATKFAAYPWR-----------LTSGQF 508
                +  G +E  +G ++ +      S + ++IA+K +  P R           L     
Sbjct: 56   PPRPETQGLTETYVGNWLAKHG----SREKLIIASKVSG-PSRNNDKGIRPDQALDRKNI 110

Query: 509  VNACRSSLERLQIDRLGIGQLHW-------------STANYAPLQERA-LWDGLVEMYDK 646
              A   SL+RLQ D L + Q+HW             S  + AP        D L E    
Sbjct: 111  REALHDSLKRLQTDYLDLYQVHWPQRPTNCFGKLGYSWTDSAPAVSLLDTLDALAEYQRA 170

Query: 647  GLVRAVGVSNYGPKQLLKIHSYLASRGVP-LSSAQVQFSLLSMGEEQMELKTVCDSLGVR 823
            G +R +GVSN     +++         +P + + Q  +SLL+   E + L  V    GV 
Sbjct: 171  GKIRYIGVSNETAFGVMRYLHLADKHDLPRIVTIQNPYSLLNRSFE-VGLAEVSQYEGVE 229

Query: 824  LIAYSPLGLGMLTGKYDASNLPNGPRSVLFRQIL----PGLESLLSCLKSIADRKGKTMS 991
            L+AYS LG G LTGKY     P G R+ LF +         +  ++    IA R G   +
Sbjct: 230  LLAYSCLGFGTLTGKYLNGAKPAGARNTLFSRFTRYSGEQTQKAVAAYVDIARRHGLDPA 289

Query: 992  QVAINWCICKG--AIPIPGVKTVRHVEDNLGALGWRLSPGEISELEA 1126
            Q+A+ +   +   A  + G  T+  ++ N+ +L   LS   ++E+EA
Sbjct: 290  QMALAFVRRQPFVASTLLGATTMDQLKTNIESLHLELSEDVLAEIEA 336
to top
>P0A9T4:TAS_ECOLI Protein tas - Escherichia coli|
          Length = 346

 Score = 82.0 bits (201), Expect = 5e-15
 Identities = 92/347 (26%), Positives = 151/347 (43%), Gaps = 35/347 (10%)
 Frame = +2

Query: 191  WEKVNVGPLSVSPMGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGT 370
            + ++    L VS +G GT  +G       E++ +++     + A+  GINL D A+ Y  
Sbjct: 3    YHRIPHSSLEVSTLGLGTMTFG-------EQNSEADAHAQLDYAVAQGINLIDVAEMYPV 55

Query: 371  G---KLNGQSERLLGKFIRECQGPIKSPDDVVIATKFAAYPWR-----------LTSGQF 508
                +  G +E  +G ++ +      S + ++IA+K +  P R           L     
Sbjct: 56   PPRPETQGLTETYVGNWLAKHG----SREKLIIASKVSG-PSRNNDKGIRPDQALDRKNI 110

Query: 509  VNACRSSLERLQIDRLGIGQLHW-------------STANYAPLQERA-LWDGLVEMYDK 646
              A   SL+RLQ D L + Q+HW             S  + AP        D L E    
Sbjct: 111  REALHDSLKRLQTDYLDLYQVHWPQRPTNCFGKLGYSWTDSAPAVSLLDTLDALAEYQRA 170

Query: 647  GLVRAVGVSNYGPKQLLKIHSYLASRGVP-LSSAQVQFSLLSMGEEQMELKTVCDSLGVR 823
            G +R +GVSN     +++         +P + + Q  +SLL+   E + L  V    GV 
Sbjct: 171  GKIRYIGVSNETAFGVMRYLHLADKHDLPRIVTIQNPYSLLNRSFE-VGLAEVSQYEGVE 229

Query: 824  LIAYSPLGLGMLTGKYDASNLPNGPRSVLFRQIL----PGLESLLSCLKSIADRKGKTMS 991
            L+AYS LG G LTGKY     P G R+ LF +         +  ++    IA R G   +
Sbjct: 230  LLAYSCLGFGTLTGKYLNGAKPAGARNTLFSRFTRYSGEQTQKAVAAYVDIARRHGLDPA 289

Query: 992  QVAINWCICKG--AIPIPGVKTVRHVEDNLGALGWRLSPGEISELEA 1126
            Q+A+ +   +   A  + G  T+  ++ N+ +L   LS   ++E+EA
Sbjct: 290  QMALAFVRRQPFVASTLLGATTMDQLKTNIESLHLELSEDVLAEIEA 336
to top
>P26690:6DCS_SOYBN NAD(P)H-dependent 6'-deoxychalcone synthase - Glycine max (Soybean)|
          Length = 315

 Score = 81.6 bits (200), Expect = 6e-15
 Identities = 71/284 (25%), Positives = 122/284 (42%), Gaps = 16/284 (5%)
 Frame = +2

Query: 296  ELQECFNLALKNGINLFDTADSYGTGKLNGQSERLLGKFIREC-QGPIKSPDDVVIATKF 472
            + +E    A+K G   FDTA +YG       SE+ LG+ ++E     + S  D+ + +K 
Sbjct: 37   DTKEAIIEAVKQGYRHFDTAAAYG-------SEQALGEALKEAIHLGLVSRQDLFVTSKL 89

Query: 473  AAYPWRLTSGQFV--NACRSSLERLQIDRLGIGQLHWSTANYA-------------PLQE 607
                W   +   +   A R SL+ LQ++ L +  +HW  ++               P   
Sbjct: 90   ----WVTENHPHLVLPALRKSLKTLQLEYLDLYLIHWPLSSQPGKFSFPIEVEDLLPFDV 145

Query: 608  RALWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSYLASRGVPLSSAQVQFSLLSMGEEQM 787
            + +W+ + E    GL +A+GVSN+  K+L  + S    R V      V    +++  +Q 
Sbjct: 146  KGVWESMEECQKLGLTKAIGVSNFSVKKLQNLLSVATIRPV------VDQVEMNLAWQQK 199

Query: 788  ELKTVCDSLGVRLIAYSPLGLGMLTGKYDASNLPNGPRSVLFRQILPGLESLLSCLKSIA 967
            +L+  C   G+ + A+SPL  G             GP  V+   +          LK IA
Sbjct: 200  KLREFCKENGIIVTAFSPLRKG----------ASRGPNEVMENDV----------LKEIA 239

Query: 968  DRKGKTMSQVAINWCICKGAIPIPGVKTVRHVEDNLGALGWRLS 1099
            +  GK+++QV++ W   +G   +P       +  NL    W L+
Sbjct: 240  EAHGKSIAQVSLRWLYEQGVTFVPKSYDKERMNQNLHIFDWALT 283
to top
>P77256:YDJG_ECOLI Uncharacterized oxidoreductase ydjG - Escherichia coli|
          Length = 326

 Score = 80.9 bits (198), Expect = 1e-14
 Identities = 85/333 (25%), Positives = 139/333 (41%), Gaps = 27/333 (8%)
 Frame = +2

Query: 215  LSVSPMGFGTWAWGNQLLWGYEESMDSELQECFNLALKN---GINLFDTADSYGTGKLNG 385
            +++S MG GTWA G    W    + D + Q C +  L+    GINL DTA  Y  G    
Sbjct: 11   ITLSRMGLGTWAIGGGPAW----NGDLDRQICIDTILEAHRCGINLIDTAPGYNFGN--- 63

Query: 386  QSERLLGKFIRECQGPIKSPDDVVIATKFAAYPWRLTSGQFVNA---------------- 517
             SE ++G+ ++      K P + V+        W      F                   
Sbjct: 64   -SEVIVGQALK------KLPREQVVVETKCGIVWERKGSLFNKVGDRQLYKNLSPESIRE 116

Query: 518  -CRSSLERLQIDRLGIGQLHWSTAN--YAPLQERALWDGLVEMYDKGLVRAVGVSNYGPK 688
               +SL+RL ID + I   HW +    + P+ E      L E+  +G +RA+G +N    
Sbjct: 117  EVAASLQRLGIDYIDIYMTHWQSVPPFFTPIAETVAV--LNELKSEGKIRAIGAANVDAD 174

Query: 689  QLLKIHSYLASRGVPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGMLTGK 868
             + +   Y       L   Q ++S+L    E  EL  +C   G+ +  YSPL  G+LTG 
Sbjct: 175  HIREYLQY-----GELDIIQAKYSILDRAMEN-ELLPLCRDNGIVVQVYSPLEQGLLTGT 228

Query: 869  YDASNLPNGPRS--VLF-RQILPGLESLLSCLKSIADRKGKTMSQVAINWCICKGAI--P 1033
                 +P G R+  V F R+ +  +  +L   + +  R   T+  +A+ W + +  +   
Sbjct: 229  ITRDYVPGGARANKVWFQRENMLKVIDMLEQWQPLCARYQCTIPTLALAWILKQSDLISI 288

Query: 1034 IPGVKTVRHVEDNLGALGWRLSPGEISELEAAA 1132
            + G      V +N+ AL   LS  + + +   A
Sbjct: 289  LSGATAPEQVRENVAALNINLSDADATLMREMA 321
to top
>P40691:A115_TOBAC Auxin-induced protein PCNT115 - Nicotiana tabacum (Common tobacco)|
          Length = 307

 Score = 80.9 bits (198), Expect = 1e-14
 Identities = 86/317 (27%), Positives = 147/317 (46%), Gaps = 21/317 (6%)
 Frame = +2

Query: 188  PWEKVNVGPLSVSPMGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYG 367
            P  K+    L VS  G G    G    +G  +  + ++ +  + A+ +GI L DT+D YG
Sbjct: 9    PRIKLGSQGLEVSAQGLG--CMGMSAFYGPPKP-EPDMIQLIHHAINSGITLLDTSDVYG 65

Query: 368  TGKLNGQSERLLGKFIRECQGPIKSPDDVVIATKFA--------AYPWRLTSGQ--FVNA 517
                   +E LLGK ++       + + VV+ATKF         A   R   G   +V A
Sbjct: 66   PHT----NEILLGKALKG-----GTRERVVLATKFGIVLGDEKKAEGKRAVHGDPAYVRA 116

Query: 518  -CRSSLERLQIDRLGIGQLHWSTANYAPLQERALWDGLVEMYDKGLVRAVGVSNYGPKQL 694
             C +SL+RL ID + +   H       P++       L ++ ++G ++ +G+S      +
Sbjct: 117  ACEASLKRLDIDCIDLYYQH-RVDTRVPIEITV--GELKKLVEEGKLKYIGLSEASASTI 173

Query: 695  LKIHSYLASRGVPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGMLTGKYD 874
             + H+       P+++ Q+++SL S   E+ E+   C  LG+ ++AYSPLG G L+    
Sbjct: 174  RRAHAVH-----PITAVQLEWSLWSRDVEE-EIIPTCRELGIGIVAYSPLGRGFLS---S 224

Query: 875  ASNLPNGPRSVLFRQILPGLE--------SLLSCLKSIADRKGKTMSQVAINWCICKG-- 1024
               L     +  +R+ LP  +        +L   +  +A RKG T SQ+A+ W   +G  
Sbjct: 225  GPKLLEDMSNEDYRKYLPRFQAENLENNKNLYERICEMAVRKGCTPSQLALAWVHHQGND 284

Query: 1025 AIPIPGVKTVRHVEDNL 1075
              PIPG   + ++  N+
Sbjct: 285  VCPIPGTTKIENLNQNM 301
to top
>P80276:ALDR_PIG Aldose reductase - Sus scrofa (Pig)|
          Length = 316

 Score = 77.4 bits (189), Expect = 1e-13
 Identities = 83/317 (26%), Positives = 135/317 (42%), Gaps = 20/317 (6%)
 Frame = +2

Query: 230  MGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQSERLLGK 409
            +G GTW           +S   ++ E   +A+  G    D A  Y       Q+E  +G 
Sbjct: 16   LGLGTW-----------KSPPGKVTEAVKVAIDLGYRHIDCAHVY-------QNENEVGL 57

Query: 410  FIRE-CQGPIKSPDDVVIATKF--AAYPWRLTSGQFVNACRSSLERLQIDRLGIGQLHWS 580
             ++E  QG +   +D+ I +K     +   L  G    AC+++L  L++D L +  +HW 
Sbjct: 58   GLQEKLQGQVVKREDLFIVSKLWCTDHEKNLVKG----ACQTTLRDLKLDYLDLYLIHWP 113

Query: 581  TA--------------NYAPLQERAL--WDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSY 712
            T               N  P +   +  W+ + E+ D+GLV+A+GVSN+   Q+ KI   
Sbjct: 114  TGFKPGKDPFPLDGDGNVVPDESDFVETWEAMEELVDEGLVKAIGVSNFNHLQVEKI--- 170

Query: 713  LASRGVPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGL-GMLTGKYDASNLP 889
            L   G+    A  Q  +      Q +L   C S G+ + AYSPLG       K +  +L 
Sbjct: 171  LNKPGLKYKPAVNQIEVHPY-LTQEKLIEYCKSKGIVVTAYSPLGSPDRPWAKPEDPSLL 229

Query: 890  NGPRSVLFRQILPGLESLLSCLKSIADRKGKTMSQVAINWCICKGAIPIPGVKTVRHVED 1069
              PR                 +K+IA +  KT +QV I + + +  I IP   T   + +
Sbjct: 230  EDPR-----------------IKAIAAKYNKTTAQVLIRFPMQRNLIVIPKSVTPERIAE 272

Query: 1070 NLGALGWRLSPGEISEL 1120
            N     + LSP +++ L
Sbjct: 273  NFQVFDFELSPEDMNTL 289
to top
>P07943:ALDR_RAT Aldose reductase - Rattus norvegicus (Rat)|
          Length = 316

 Score = 72.8 bits (177), Expect = 3e-12
 Identities = 80/317 (25%), Positives = 129/317 (40%), Gaps = 20/317 (6%)
 Frame = +2

Query: 230  MGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQSERLLGK 409
            +G GTW           +S   ++ E   +A+  G    D A  Y       Q+E+ +G 
Sbjct: 16   LGLGTW-----------KSPPGQVTEAVKVAIDMGYRHIDCAQVY-------QNEKEVGV 57

Query: 410  FIRE-CQGPIKSPDDVVIATKFAAYPWRLTSGQFV--NACRSSLERLQIDRLGIGQLHWS 580
             ++E  +  +    D+ I +K     W     Q +   AC+ +L  LQ+D L +  +HW 
Sbjct: 58   ALQEKLKEQVVKRQDLFIVSKL----WCTFHDQSMVKGACQKTLSDLQLDYLDLYLIHWP 113

Query: 581  TA-----NYAPLQERA-----------LWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSY 712
            T      +Y PL                W  + ++ D+GLV+A+GVSN+ P Q+ +I   
Sbjct: 114  TGFKPGPDYFPLDASGNVIPSDTDFVDTWTAMEQLVDEGLVKAIGVSNFNPLQIERI--- 170

Query: 713  LASRGVPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGL-GMLTGKYDASNLP 889
            L   G+    A  Q         Q +L   C   G+ + AYSPLG       K +  +L 
Sbjct: 171  LNKPGLKYKPAVNQIECHPY-LTQEKLIEYCHCKGIVVTAYSPLGSPDRPWAKPEDPSLL 229

Query: 890  NGPRSVLFRQILPGLESLLSCLKSIADRKGKTMSQVAINWCICKGAIPIPGVKTVRHVED 1069
              PR                 +K IA +  KT +QV I + I +  + IP   T   + +
Sbjct: 230  EDPR-----------------IKEIAAKYNKTTAQVLIRFPIQRNLVVIPKSVTPARIAE 272

Query: 1070 NLGALGWRLSPGEISEL 1120
            N     + LS  +++ L
Sbjct: 273  NFKVFDFELSNEDMATL 289
to top
>P16116:ALDR_BOVIN Aldose reductase - Bos taurus (Bovine)|
          Length = 315

 Score = 72.8 bits (177), Expect = 3e-12
 Identities = 81/317 (25%), Positives = 132/317 (41%), Gaps = 20/317 (6%)
 Frame = +2

Query: 230  MGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQSERLLGK 409
            +G GTW           +S   ++ E   +A+  G    D A  Y       Q+E  +G 
Sbjct: 15   LGLGTW-----------KSPPGKVTEAVKVAIDLGYRHIDCAHVY-------QNENEVGL 56

Query: 410  FIR-ECQGPIKSPDDVVIATKF--AAYPWRLTSGQFVNACRSSLERLQIDRLGIGQLHWS 580
             ++ + Q  +   +D+ I +K     +   L  G    AC+ +L  L++D L +  +HW 
Sbjct: 57   ALQAKLQEQVVKREDLFIVSKLWCTYHDKDLVKG----ACQKTLSDLKLDYLDLYLIHWP 112

Query: 581  TA-----NYAPLQERA-----------LWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSY 712
            T      ++ PL E              W  + E+ D+GLV+A+GVSN+   Q+ KI   
Sbjct: 113  TGFKPGKDFFPLDEDGNVIPSEKDFVDTWTAMEELVDEGLVKAIGVSNFNHLQVEKI--- 169

Query: 713  LASRGVPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGL-GMLTGKYDASNLP 889
            L   G+    A  Q         Q +L   C+S G+ + AYSPLG       K +  ++ 
Sbjct: 170  LNKPGLKYKPAVNQIECHPY-LTQEKLIQYCNSKGIVVTAYSPLGSPDRPWAKPEDPSIL 228

Query: 890  NGPRSVLFRQILPGLESLLSCLKSIADRKGKTMSQVAINWCICKGAIPIPGVKTVRHVED 1069
              PR                 +K+IAD+  KT +QV I + I +  I IP   T   + +
Sbjct: 229  EDPR-----------------IKAIADKYNKTTAQVLIRFPIQRNLIVIPKSVTPERIAE 271

Query: 1070 NLGALGWRLSPGEISEL 1120
            N     + L   +++ L
Sbjct: 272  NFQVFDFELDKEDMNTL 288
to top
>Q8XBT6:DKGA_ECO57 2,5-diketo-D-gluconic acid reductase A - Escherichia coli O157:H7|
          Length = 275

 Score = 71.6 bits (174), Expect = 7e-12
 Identities = 65/287 (22%), Positives = 125/287 (43%)
 Frame = +2

Query: 260  QLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQSERLLGKFIRECQGPIK 439
            QL  G  ++ + E+      AL+ G   FDTA +Y       ++E  +GK ++       
Sbjct: 17   QLGLGVWQASNEEVITAIQKALEVGYRSFDTAAAY-------KNEEGVGKALKNAS---V 66

Query: 440  SPDDVVIATKFAAYPWRLTSGQFVNACRSSLERLQIDRLGIGQLHWSTANYAPLQERALW 619
            + +++ I TK     W     +   A   SL++LQ+D + +  +HW         E   W
Sbjct: 67   NREELFITTKL----WNDDHNRPREALLDSLKKLQLDYIDLYLMHWPVPAIDHYVEA--W 120

Query: 620  DGLVEMYDKGLVRAVGVSNYGPKQLLKIHSYLASRGVPLSSAQVQFSLLSMGEEQMELKT 799
             G++E+  +GL++++GV N+   Q+  +   +   GV     Q++   L    +Q +L  
Sbjct: 121  KGMIELQKEGLIKSIGVCNF---QIHHLQRLIDETGVTPVINQIELHPLM---QQRQLHA 174

Query: 800  VCDSLGVRLIAYSPLGLGMLTGKYDASNLPNGPRSVLFRQILPGLESLLSCLKSIADRKG 979
               +  ++  ++SPL                G + V  ++++          + +AD+ G
Sbjct: 175  WNATHKIQTESWSPLA--------------QGGKGVFDQKVI----------RDLADKYG 210

Query: 980  KTMSQVAINWCICKGAIPIPGVKTVRHVEDNLGALGWRLSPGEISEL 1120
            KT +Q+ I W +  G + IP   T   + +N     +RL   E+ E+
Sbjct: 211  KTPAQIVIRWHLDSGLVVIPKSVTPSRIAENFDVWDFRLDKDELGEI 257
to top
>P47137:YJ66_YEAST Probable oxidoreductase YJR096W - Saccharomyces cerevisiae (Baker's|
            yeast)
          Length = 282

 Score = 71.2 bits (173), Expect = 9e-12
 Identities = 79/287 (27%), Positives = 125/287 (43%), Gaps = 10/287 (3%)
 Frame = +2

Query: 293  SELQECFNLALKNGINLFDTADSYGTGKLNGQSERLLGKFIRECQGPIKSPDDVVIATKF 472
            S+  E     +K G   FDTA  YG  K  G     + K++ E  G  K  +++   TK 
Sbjct: 27   SQTAEIVYEGVKCGYRHFDTAVLYGNEKEVGDG---IIKWLNEDPGNHKR-EEIFYTTKL 82

Query: 473  AAYPWRLTSGQ-----FVNACRSSLERLQ-IDRLGIGQLHWSTANYAPLQERAL----WD 622
                W   +G       +  C + +  LQ ID L I         ++PL+   L    W 
Sbjct: 83   ----WNSQNGYKRAKAAIRQCLNEVSGLQYIDLLLI---------HSPLEGSKLRLETWR 129

Query: 623  GLVEMYDKGLVRAVGVSNYGPKQLLKIHSYLASRGVPLSSAQVQFSLLSMGEEQMELKTV 802
             + E  D+GLV+++GVSNYG K + ++ ++   +  P+ + Q++ S   M   + EL   
Sbjct: 130  AMQEAVDEGLVKSIGVSNYGKKHIDELLNWPELKHKPVVN-QIEISPWIM---RQELADY 185

Query: 803  CDSLGVRLIAYSPLGLGMLTGKYDASNLPNGPRSVLFRQILPGLESLLSCLKSIADRKGK 982
            C S G+ + A++PL  G     Y  +N                   LL   K +    G 
Sbjct: 186  CKSKGLVVEAFAPLCHG-----YKMTN-----------------PDLLKVCKEVDRNPG- 222

Query: 983  TMSQVAINWCICKGAIPIPGVKTVRHVEDNLGALGWRLSPGEISELE 1123
               QV I W +  G +P+P  KTV+ +E NL A  + LS  ++  L+
Sbjct: 223  ---QVLIRWSLQHGYLPLPKTKTVKRLEGNLAAYNFELSDEQMKFLD 266
to top
>P58744:DKGA_SALTI 2,5-diketo-D-gluconic acid reductase A - Salmonella typhi|
          Length = 275

 Score = 71.2 bits (173), Expect = 9e-12
 Identities = 67/287 (23%), Positives = 124/287 (43%)
 Frame = +2

Query: 260  QLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQSERLLGKFIRECQGPIK 439
            QL  G  ++ + E+    + AL+ G    DTA +Y       Q+E  +GK ++       
Sbjct: 17   QLGLGVWKASNEEVIAAIHKALEVGYRSIDTATAY-------QNEEGVGKALKAAS---V 66

Query: 440  SPDDVVIATKFAAYPWRLTSGQFVNACRSSLERLQIDRLGIGQLHWSTANYAPLQERALW 619
            + +++ I TK     W     +   A + SL++LQ+D L +  +HW         +   W
Sbjct: 67   AREELFITTKL----WNDDQKRPREALQESLKKLQLDYLDLYLMHWPVPAIDHYVDA--W 120

Query: 620  DGLVEMYDKGLVRAVGVSNYGPKQLLKIHSYLASRGVPLSSAQVQFSLLSMGEEQMELKT 799
             G++ +  +GLV+++GV N+   Q+  +   +   GVP    Q++   L    +Q +L  
Sbjct: 121  KGMIALQKEGLVKSIGVCNF---QIHHLQRLIDETGVPPVINQIELHPLM---QQRQLHA 174

Query: 800  VCDSLGVRLIAYSPLGLGMLTGKYDASNLPNGPRSVLFRQILPGLESLLSCLKSIADRKG 979
               +  ++  ++SPL  G   G +D                          ++ +AD+ G
Sbjct: 175  WNATHKIQTESWSPLAQGG-EGVFDQK-----------------------VIRELADKYG 210

Query: 980  KTMSQVAINWCICKGAIPIPGVKTVRHVEDNLGALGWRLSPGEISEL 1120
            KT +Q+ I W +  G + IP   T   + +N     +RL   E+ E+
Sbjct: 211  KTPAQIVIRWHLDCGLVVIPKSVTPSRIAENFAVWDFRLDKDELGEI 257
to top
>P28475:S6PD_MALDO NADP-dependent D-sorbitol-6-phosphate dehydrogenase - Malus domestica|
            (Apple) (Malus sylvestris)
          Length = 310

 Score = 70.9 bits (172), Expect = 1e-11
 Identities = 78/300 (26%), Positives = 133/300 (44%), Gaps = 22/300 (7%)
 Frame = +2

Query: 266  LWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQSERLLGKFIREC--QGPIK 439
            LW  E+    EL+E    A+K G   FD A  Y       +SE  +G+ + E    G +K
Sbjct: 19   LWRLEKD---ELKEVILNAIKIGYRHFDCAAHY-------KSEADVGEALAEAFKTGLVK 68

Query: 440  SPDDVVIATKFAAYPWRLTSGQFVNACRSSLERLQIDRLGIGQLHW----------STAN 589
              +++ I TK     W    G  V AC++SLE+LQID L +  +H+           TA+
Sbjct: 69   R-EELFITTKI----WNSDHGHVVEACKNSLEKLQIDYLDLYLVHYPMPTKHNAIGKTAS 123

Query: 590  Y----------APLQERALWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSYLASRGVPLS 739
                         +  +  W+G+ +    GLVR++G+SNY   +L      LA   +  +
Sbjct: 124  LLGEDKVLDIDVTISLQQTWEGMEKTVSLGLVRSIGLSNY---ELFLTRDCLAYSKIKPA 180

Query: 740  SAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGMLTGKYDASNLPNGPRSVLFRQ 919
             +Q +        ++  L   C   GV   A++PLG G    K             +F  
Sbjct: 181  VSQFETHPYF---QRDSLVKFCMKHGVLPTAHTPLG-GAAANK------------DMFGS 224

Query: 920  ILPGLESLLSCLKSIADRKGKTMSQVAINWCICKGAIPIPGVKTVRHVEDNLGALGWRLS 1099
            + P  + +L+    +A + GK+++Q+ + W I +    IP    ++ +++NL  L ++LS
Sbjct: 225  VSPLDDPVLN---DVAKKYGKSVAQICLRWGIQRKTAVIPKSSKIQRLKENLEVLEFQLS 281
to top
>P15121:ALDR_HUMAN Aldose reductase - Homo sapiens (Human)|
          Length = 316

 Score = 70.5 bits (171), Expect = 1e-11
 Identities = 76/316 (24%), Positives = 129/316 (40%), Gaps = 19/316 (6%)
 Frame = +2

Query: 230  MGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQSERLLGK 409
            +G GTW           +S   ++ E   +A+  G    D A  Y       Q+E  +G 
Sbjct: 16   LGLGTW-----------KSPPGQVTEAVKVAIDVGYRHIDCAHVY-------QNENEVGV 57

Query: 410  FIREC--QGPIKSPDDVVIATKFAAYPWRLTSGQFVNACRSSLERLQIDRLGIGQLHWST 583
             I+E   +  +K  +  +++  +  Y  +   G    AC+ +L  L++D L +  +HW T
Sbjct: 58   AIQEKLREQVVKREELFIVSKLWCTYHEK---GLVKGACQKTLSDLKLDYLDLYLIHWPT 114

Query: 584  A-----NYAPLQERA-----------LWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSYL 715
                   + PL E              W  + E+ D+GLV+A+G+SN+     L++   L
Sbjct: 115  GFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNH---LQVEMIL 171

Query: 716  ASRGVPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGL-GMLTGKYDASNLPN 892
               G+    A  Q         Q +L   C S G+ + AYSPLG       K +  +L  
Sbjct: 172  NKPGLKYKPAVNQIECHPY-LTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLE 230

Query: 893  GPRSVLFRQILPGLESLLSCLKSIADRKGKTMSQVAINWCICKGAIPIPGVKTVRHVEDN 1072
             PR                 +K+IA +  KT +QV I + + +  + IP   T   + +N
Sbjct: 231  DPR-----------------IKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAEN 273

Query: 1073 LGALGWRLSPGEISEL 1120
                 + LS  +++ L
Sbjct: 274  FKVFDFELSSQDMTTL 289
to top
>Q8VC28:AK1CD_MOUSE Aldo-keto reductase family 1 member C13 - Mus musculus (Mouse)|
          Length = 323

 Score = 70.5 bits (171), Expect = 1e-11
 Identities = 86/327 (26%), Positives = 147/327 (44%), Gaps = 18/327 (5%)
 Frame = +2

Query: 197  KVNVGPLSVSPMGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGK 376
            K+N G L +  +GFGT+          +E   S+  E   LAL  G    DTA +Y    
Sbjct: 9    KLNDGHL-IPALGFGTYK--------PKEVPKSKSLEAACLALDVGYRHVDTAYAY---- 55

Query: 377  LNGQSERLLGKFIR-ECQGPIKSPDDVVIATKFAAYPWRLTSGQFVN-ACRSSLERLQID 550
               Q E  +G+ I+ + +  +   +D+ I TK     +R    + V  A   SL++LQ+D
Sbjct: 56   ---QVEEEIGQAIQSKIKAGVVKREDLFITTKLWCTCFR---PELVKPALEKSLKKLQLD 109

Query: 551  RLGIGQLHW-----STANYAPLQERA-----------LWDGLVEMYDKGLVRAVGVSNYG 682
             + +  +H+     S  N  P+ E+             W+ L E  D GLV+++GVSN+ 
Sbjct: 110  YVDLYIMHYPVPMKSGDNDFPVNEQGKSLLDTVDFCDTWERLEECKDAGLVKSIGVSNFN 169

Query: 683  PKQLLKIHSYLASRGVPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGMLT 862
             +QL +I +    +  P+ + QV+  L      Q +L   C+S  + L+AY  LG    T
Sbjct: 170  HRQLERILNKPGLKYKPVCN-QVECHLYL---NQRKLLDYCESKDIVLVAYGALG----T 221

Query: 863  GKYDASNLPNGPRSVLFRQILPGLESLLSCLKSIADRKGKTMSQVAINWCICKGAIPIPG 1042
             +Y      N P  VL              L  +A +  ++ + +A+ + I +G +P+  
Sbjct: 222  QRYKEWVDQNSP--VLLND---------PVLCDVAKKNKRSPALIALRYLIQRGIVPLAQ 270

Query: 1043 VKTVRHVEDNLGALGWRLSPGEISELE 1123
                  + +NL   G++LSP ++  L+
Sbjct: 271  SFKENEMRENLQVFGFQLSPEDMKTLD 297
to top
>P50578:AK1A1_PIG Alcohol dehydrogenase [NADP+] - Sus scrofa (Pig)|
          Length = 325

 Score = 70.1 bits (170), Expect = 2e-11
 Identities = 75/319 (23%), Positives = 128/319 (40%), Gaps = 20/319 (6%)
 Frame = +2

Query: 230  MGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQSERLLGK 409
            +G GTW           +S   +++     AL  G    D A  YG       +E  +G+
Sbjct: 17   IGLGTW-----------KSEPGQVKAAIKYALTVGYRHIDCAAIYG-------NELEIGE 58

Query: 410  FIRECQGPIKSPDDVVIATKFAAYPWRLTSGQFVNACRSSLERLQIDRLGIGQLHW---- 577
             + E  GP K+     +      +  +        A R +L  LQ++ L +  +HW    
Sbjct: 59   ALTETVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAF 118

Query: 578  ------------STANYAPLQERALWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSYLAS 721
                         T  Y     +  W  L  +  KGLVRA+G+SN+  +Q+  +      
Sbjct: 119  ERGDNPFPKNADGTIRYDATHYKDTWKALEALVAKGLVRALGLSNFSSRQIDDV------ 172

Query: 722  RGVPLSSAQVQFSLLSMG----EEQMELKTVCDSLGVRLIAYSPLGLGMLTGKYDASNLP 889
                LS A V+ ++L +       Q EL   C + G+ + AYSPLG         A   P
Sbjct: 173  ----LSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLG-----SSDRAWRDP 223

Query: 890  NGPRSVLFRQILPGLESLLSCLKSIADRKGKTMSQVAINWCICKGAIPIPGVKTVRHVED 1069
            N P  VL  +           ++++A++  ++ +Q+ + W + +  I IP   T   +  
Sbjct: 224  NEP--VLLEE---------PVVQALAEKYNRSPAQILLRWQVQRKVICIPKSVTPSRIPQ 272

Query: 1070 NLGALGWRLSPGEISELEA 1126
            N+    +  SP E+ +L+A
Sbjct: 273  NIQVFDFTFSPEEMKQLDA 291
to top
>Q09632:YOF5_CAEEL Probable oxidoreductase ZK1290.5 - Caenorhabditis elegans|
          Length = 321

 Score = 69.3 bits (168), Expect = 3e-11
 Identities = 70/273 (25%), Positives = 117/273 (42%), Gaps = 6/273 (2%)
 Frame = +2

Query: 326  KNGINLFDTADSYGTGKLNGQSERLLGKFIRECQGPIKSPDDVVIATKFAAYPWRLTSGQ 505
            K G  L DTA  YG        E+ LG  ++ C  P    +++ ++TK     W +  G 
Sbjct: 37   KCGYRLIDTAKRYGV-------EKQLGIAVKNCSVP---REEMFLSTKL----WPVDCGD 82

Query: 506  FV-NACRSSLERLQIDRLGIGQLHWST-----ANYAPLQERALWDGLVEMYDKGLVRAVG 667
             V NA ++S E+LQ D L +  +H         N    +E+  W  +  +Y+   VR++G
Sbjct: 83   EVYNAFQTSCEKLQTDYLDMYMIHMPQLPDWIVNQKETKEKT-WRQMELLYEDEHVRSIG 141

Query: 668  VSNYGPKQLLKIHSYLASRGVPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLG 847
            VSNY  + L ++  + +   +   + QV+   L     Q +LK  CD LG+  + Y PL 
Sbjct: 142  VSNYSIEDLDELLEFAS---ILPHANQVE---LHPWFHQADLKNYCDELGILTMGYCPLA 195

Query: 848  LGMLTGKYDASNLPNGPRSVLFRQILPGLESLLSCLKSIADRKGKTMSQVAINWCICKGA 1027
                 GKY                    LE    C   IA +  K+ +Q+ + W I +  
Sbjct: 196  ----KGKY--------------------LEDETLC--KIASKYQKSPAQICLRWSIQQNV 229

Query: 1028 IPIPGVKTVRHVEDNLGALGWRLSPGEISELEA 1126
              +P     R +++N     + LS  +++ L +
Sbjct: 230  PTVPKSTDCRRLKENTNVFDFELSAEDMNTLNS 262
to top
>P51635:AK1A1_RAT Alcohol dehydrogenase [NADP+] - Rattus norvegicus (Rat)|
          Length = 325

 Score = 68.9 bits (167), Expect = 4e-11
 Identities = 72/319 (22%), Positives = 129/319 (40%), Gaps = 20/319 (6%)
 Frame = +2

Query: 230  MGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQSERLLGK 409
            +G GTW           +S   +++     AL  G    D A  YG       +E  +G+
Sbjct: 17   IGLGTW-----------KSEPGQVKAAIKYALSVGYRHIDCASVYG-------NETEIGE 58

Query: 410  FIRECQGPIKSPDDVVIATKFAAYPWRLTSGQFVNACRSSLERLQIDRLGIGQLHW---- 577
             ++E  G  K+     +      +  +        A R +L  LQ++ L +  +HW    
Sbjct: 59   ALKESVGAGKAVPREELFVTSKLWNTKHHPEDVEPAVRKTLADLQLEYLDLYLMHWPYAF 118

Query: 578  ------------STANYAPLQERALWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSYLAS 721
                         T  Y     +  W  L  +  KGLV+A+G+SN+  +Q+  +      
Sbjct: 119  ERGDNPFPKNADGTVKYDSTHYKETWKALEALVAKGLVKALGLSNFSSRQIDDV------ 172

Query: 722  RGVPLSSAQVQFSLLSMG----EEQMELKTVCDSLGVRLIAYSPLGLGMLTGKYDASNLP 889
                LS A V+ ++L +       Q EL   C + G+ + AYSPLG      ++     P
Sbjct: 173  ----LSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRH-----P 223

Query: 890  NGPRSVLFRQILPGLESLLSCLKSIADRKGKTMSQVAINWCICKGAIPIPGVKTVRHVED 1069
            + P  VL  +           + ++A++ G++ +Q+ + W + +  I IP   T   +  
Sbjct: 224  DEP--VLLEE---------PVVLALAEKHGRSPAQILLRWQVQRKVICIPKSITPSRILQ 272

Query: 1070 NLGALGWRLSPGEISELEA 1126
            N+    +  SP E+ +L+A
Sbjct: 273  NIQVFDFTFSPEEMKQLDA 291
to top
>Q46857:DKGA_ECOLI 2,5-diketo-D-gluconic acid reductase A - Escherichia coli|
          Length = 275

 Score = 68.6 bits (166), Expect = 6e-11
 Identities = 64/287 (22%), Positives = 124/287 (43%)
 Frame = +2

Query: 260  QLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQSERLLGKFIRECQGPIK 439
            QL  G  ++ + E+      AL+ G    DTA +Y       ++E  +GK ++       
Sbjct: 17   QLGLGVWQASNEEVITAIQKALEVGYRSIDTAAAY-------KNEEGVGKALKNAS---V 66

Query: 440  SPDDVVIATKFAAYPWRLTSGQFVNACRSSLERLQIDRLGIGQLHWSTANYAPLQERALW 619
            + +++ I TK     W     +   A   SL++LQ+D + +  +HW         E   W
Sbjct: 67   NREELFITTKL----WNDDHKRPREALLDSLKKLQLDYIDLYLMHWPVPAIDHYVEA--W 120

Query: 620  DGLVEMYDKGLVRAVGVSNYGPKQLLKIHSYLASRGVPLSSAQVQFSLLSMGEEQMELKT 799
             G++E+  +GL++++GV N+   Q+  +   +   GV     Q++   L    +Q +L  
Sbjct: 121  KGMIELQKEGLIKSIGVCNF---QIHHLQRLIDETGVTPVINQIELHPLM---QQRQLHA 174

Query: 800  VCDSLGVRLIAYSPLGLGMLTGKYDASNLPNGPRSVLFRQILPGLESLLSCLKSIADRKG 979
               +  ++  ++SPL                G + V  ++++          + +AD+ G
Sbjct: 175  WNATHKIQTESWSPLA--------------QGGKGVFDQKVI----------RDLADKYG 210

Query: 980  KTMSQVAINWCICKGAIPIPGVKTVRHVEDNLGALGWRLSPGEISEL 1120
            KT +Q+ I W +  G + IP   T   + +N     +RL   E+ E+
Sbjct: 211  KTPAQIVIRWHLDSGLVVIPKSVTPSRIAENFDVWDFRLDKDELGEI 257
to top
>P45376:ALDR_MOUSE Aldose reductase - Mus musculus (Mouse)|
          Length = 316

 Score = 68.6 bits (166), Expect = 6e-11
 Identities = 78/317 (24%), Positives = 130/317 (41%), Gaps = 20/317 (6%)
 Frame = +2

Query: 230  MGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQSERLLGK 409
            +G GTW           +S   ++ E   +A+  G    D A  Y       Q+E+ +G 
Sbjct: 16   LGLGTW-----------KSPPGQVTEAVKVAIDLGYRHIDCAQVY-------QNEKEVGV 57

Query: 410  FIRE-CQGPIKSPDDVVIATKF--AAYPWRLTSGQFVNACRSSLERLQIDRLGIGQLHWS 580
             ++E  +  +    D+ I +K     +   +  G F    + +L  LQ+D L +  +HW 
Sbjct: 58   ALQEKLKEQVVKRQDLFIVSKLWCTFHDKSMVKGAF----QKTLSDLQLDYLDLYLIHWP 113

Query: 581  TA-----NYAPLQERA-----------LWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSY 712
            T      +Y PL                W  + ++ D+GLV+ +GVSN+ P Q+ +I   
Sbjct: 114  TGFKPGPDYFPLDASGNVIPSDTDFVDTWTAMEQLVDEGLVKTIGVSNFNPLQIERI--- 170

Query: 713  LASRGVPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGL-GMLTGKYDASNLP 889
            L   G+    A  Q         Q +L   C S G+ + AYSPLG       K +  +L 
Sbjct: 171  LNKPGLKYKPAVNQIECHPY-LTQEKLIEYCHSKGIVVTAYSPLGSPDRPWAKPEDPSLL 229

Query: 890  NGPRSVLFRQILPGLESLLSCLKSIADRKGKTMSQVAINWCICKGAIPIPGVKTVRHVED 1069
              PR                 +K+IA +  KT +QV I + I +  + IP   T   + +
Sbjct: 230  EDPR-----------------IKAIAAKYNKTTAQVLIRFPIQRNLVVIPKSVTPVRIAE 272

Query: 1070 NLGALGWRLSPGEISEL 1120
            NL    + +S  +++ L
Sbjct: 273  NLKVFDFEVSSEDMATL 289
to top
>Q8ZM06:DKGA_SALTY 2,5-diketo-D-gluconic acid reductase A - Salmonella typhimurium|
          Length = 275

 Score = 68.2 bits (165), Expect = 7e-11
 Identities = 66/287 (22%), Positives = 123/287 (42%)
 Frame = +2

Query: 260  QLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQSERLLGKFIRECQGPIK 439
            QL  G  ++ + E+    + AL+ G    DTA +Y       Q+E  +GK ++       
Sbjct: 17   QLGLGVWKASNEEVIAAIHKALEVGYRSIDTATAY-------QNEEGVGKALKAAS---V 66

Query: 440  SPDDVVIATKFAAYPWRLTSGQFVNACRSSLERLQIDRLGIGQLHWSTANYAPLQERALW 619
            + +++ I TK     W     +   A + SL++LQ+D L +  +HW         +   W
Sbjct: 67   AREELFITTKL----WNDDQKRPREALQESLKKLQLDYLDLYLMHWPVPAIDHYVDA--W 120

Query: 620  DGLVEMYDKGLVRAVGVSNYGPKQLLKIHSYLASRGVPLSSAQVQFSLLSMGEEQMELKT 799
             G++ +  +GLV+++GV N+   Q+  +   +   GV     Q++   L    +Q +L  
Sbjct: 121  KGMIALQKEGLVKSIGVCNF---QIHHLQRLIDETGVTPVINQIELHPLM---QQRQLHA 174

Query: 800  VCDSLGVRLIAYSPLGLGMLTGKYDASNLPNGPRSVLFRQILPGLESLLSCLKSIADRKG 979
               +  ++  ++SPL  G   G +D                          ++ +AD+ G
Sbjct: 175  WNATHKIQTESWSPLAQGG-EGVFDQK-----------------------VIRELADKYG 210

Query: 980  KTMSQVAINWCICKGAIPIPGVKTVRHVEDNLGALGWRLSPGEISEL 1120
            KT +Q+ I W +  G + IP   T   + +N     +RL   E+ E+
Sbjct: 211  KTPAQIVIRWHLDCGLVVIPKSVTPSRIAENFAVWDFRLDKDELGEI 257
to top
>P15122:ALDR_RABIT Aldose reductase - Oryctolagus cuniculus (Rabbit)|
          Length = 316

 Score = 67.8 bits (164), Expect = 1e-10
 Identities = 77/317 (24%), Positives = 131/317 (41%), Gaps = 20/317 (6%)
 Frame = +2

Query: 230  MGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQSERLLGK 409
            +G GTW           +S   ++ E    A+  G    D A  Y       Q+E  +G 
Sbjct: 16   LGLGTW-----------KSPPGQVTEAVKTAIDLGYRHIDCAHVY-------QNENEVGV 57

Query: 410  FIRE-CQGPIKSPDDVVIATKF--AAYPWRLTSGQFVNACRSSLERLQIDRLGIGQLHWS 580
             ++E  +  +   +++ I +K    ++   L  G    AC+ +L  L++D L +  +HW 
Sbjct: 58   ALQEKLKEQVVKREELFIVSKLWCTSHDKSLVKG----ACQKTLNDLKLDYLDLYLIHWP 113

Query: 581  T-----ANYAPLQERA-----------LWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSY 712
            T     + Y PL                W+ +  + D+GLV+++GVSN+   Q+ +I   
Sbjct: 114  TGFKHGSEYFPLDAAGNVIPSDTDFLDTWEAMEGLVDEGLVKSIGVSNFNHLQIERI--- 170

Query: 713  LASRGVPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGL-GMLTGKYDASNLP 889
            L   G+    A  Q         Q +L   C S G+ + AYSPLG       K +  +L 
Sbjct: 171  LNKPGLKYKPAVNQIECHPY-LTQEKLIQYCHSKGIVVTAYSPLGSPDRPWAKPEDPSLL 229

Query: 890  NGPRSVLFRQILPGLESLLSCLKSIADRKGKTMSQVAINWCICKGAIPIPGVKTVRHVED 1069
              PR                 +K+IAD+  KT +QV I + + +  + IP   T   + +
Sbjct: 230  EDPR-----------------IKAIADKHKKTTAQVLIRFPMQRNLVVIPKSVTPARIAE 272

Query: 1070 NLGALGWRLSPGEISEL 1120
            N     + LS  +++ L
Sbjct: 273  NFQVFDFELSSEDMTTL 289
to top
>P45377:ALD2_MOUSE Aldose reductase-related protein 2 - Mus musculus (Mouse)|
          Length = 316

 Score = 67.0 bits (162), Expect = 2e-10
 Identities = 74/317 (23%), Positives = 136/317 (42%), Gaps = 20/317 (6%)
 Frame = +2

Query: 230  MGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQS--ERLL 403
            +G GTW           +S  ++++E    A+  G    D A +Y      G++  E++ 
Sbjct: 16   VGLGTW-----------KSPPNQVKEAVKAAIDAGYRHIDCAYAYCNENEVGEAIQEKIK 64

Query: 404  GKFIRECQGPIKSPDDVVIATKFAAYPWRLTSGQFVNACRSSLERLQIDRLGIGQLHWST 583
             K ++         +D+ I +K   +P          A + +L  L++D L +  +HW  
Sbjct: 65   EKAVQR--------EDLFIVSKL--WPTCFEKKLLKEAFQKTLTDLKLDYLDLYLIHWPQ 114

Query: 584  A-----NYAPLQERA-----------LWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSYL 715
                     P  ++             W+G+ E+ D+GLV+A+GVSN+   Q+ ++ +  
Sbjct: 115  GLQPGKELFPKDDQGRILTSKTTFLEAWEGMEELVDQGLVKALGVSNFNHFQIERLLNKP 174

Query: 716  ASRGVPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGMLTGKYDASNLPNG 895
              +  P+++       L+    Q +L   C S G+ + AYSPLG             P+ 
Sbjct: 175  GLKHKPVTNQVECHPYLT----QEKLIQYCHSKGISVTAYSPLG------------SPDR 218

Query: 896  PRSVLFRQILPGLESLLS--CLKSIADRKGKTMSQVAINWCICKGAIPIPGVKTVRHVED 1069
            P +       P   SLL    +K IA +  KT +QV I + I +  + IP   T   +++
Sbjct: 219  PSA------KPEDPSLLEDPKIKEIAAKHEKTSAQVLIRFHIQRNVVVIPKSVTPSRIQE 272

Query: 1070 NLGALGWRLSPGEISEL 1120
            N+    ++LS  E++ +
Sbjct: 273  NIQVFDFQLSDEEMATI 289
to top
>P06632:DKGA_CORSC 2,5-diketo-D-gluconic acid reductase A - Corynebacterium sp. (strain|
            ATCC 31090)
          Length = 278

 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 76/294 (25%), Positives = 125/294 (42%), Gaps = 5/294 (1%)
 Frame = +2

Query: 260  QLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQSERLLGKFIRECQGPIK 439
            QL +G  +   ++ Q     AL+ G    DTA  YG  +  G +    G           
Sbjct: 16   QLGYGVFKVPPADTQRAVEEALEVGYRHIDTAAIYGNEEGVGAAIAASGI---------- 65

Query: 440  SPDDVVIATKFAAYPW--RLTSGQFVNACRSSLERLQIDRLGIGQLHWSTA---NYAPLQ 604
            + DD+ I TK     W  R    +   A   SL +L +D++ +  +HW T    NY    
Sbjct: 66   ARDDLFITTKL----WNDRHDGDEPAAAIAESLAKLALDQVDLYLVHWPTPAADNYVHA- 120

Query: 605  ERALWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSYLASRGVPLSSAQVQFSLLSMGEEQ 784
                W+ ++E+   GL R++GVSN+    L +I   +A+ GV  +  Q++   L    +Q
Sbjct: 121  ----WEKMIELRAAGLTRSIGVSNHLVPHLERI---VAATGVVPAVNQIE---LHPAYQQ 170

Query: 785  MELKTVCDSLGVRLIAYSPLGLGMLTGKYDASNLPNGPRSVLFRQILPGLESLLSCLKSI 964
             E+     +  V++ ++ PLG     GKYD                L G E + +     
Sbjct: 171  REITDWAAAHDVKIESWGPLG----QGKYD----------------LFGAEPVTAA---- 206

Query: 965  ADRKGKTMSQVAINWCICKGAIPIPGVKTVRHVEDNLGALGWRLSPGEISELEA 1126
            A   GKT +Q  + W + KG +  P       +E+NL    + L+  EI+ ++A
Sbjct: 207  AAAHGKTPAQAVLRWHLQKGFVVFPKSVRRERLEENLDVFDFDLTDTEIAAIDA 260
to top
>P23901:ALDR_HORVU Aldose reductase - Hordeum vulgare (Barley)|
          Length = 320

 Score = 66.2 bits (160), Expect = 3e-10
 Identities = 64/301 (21%), Positives = 116/301 (38%), Gaps = 12/301 (3%)
 Frame = +2

Query: 230  MGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQSERLLGK 409
            +G GTW  G+        S+ + + E        G    DTA  YG        E+ +GK
Sbjct: 27   VGLGTWRAGSDTA----HSVRTAITEA-------GYRHVDTAAEYGV-------EKEVGK 68

Query: 410  FIRECQGPIKSPDDVVIATKFAAYPWRLTSGQFVNACRSSLERLQIDRLGIGQLHW---- 577
             ++          D+ + +K   +   L   +   A  ++L+ LQ+D + +  +HW    
Sbjct: 69   GLKAAMEAGIDRKDLFVTSKI--WCTNLAPERVRPALENTLKDLQLDYIDLYHIHWPFRL 126

Query: 578  --------STANYAPLQERALWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSYLASRGVP 733
                                +W  +  +   GLV+ +GV NY    + K++  L S  +P
Sbjct: 127  KDGAHMPPEAGEVLEFDMEGVWKEMENLVKDGLVKDIGVCNY---TVTKLNRLLRSAKIP 183

Query: 734  LSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGMLTGKYDASNLPNGPRSVLF 913
             +  Q++   +  G +  ++   C   G+ + AYSPLG           NL + P     
Sbjct: 184  PAVCQME---MHPGWKNDKIFEACKKHGIHVTAYSPLGSS-------EKNLAHDP----- 228

Query: 914  RQILPGLESLLSCLKSIADRKGKTMSQVAINWCICKGAIPIPGVKTVRHVEDNLGALGWR 1093
                         ++ +A++  KT  QV I W + +G   IP       +++N+   GW 
Sbjct: 229  ------------VVEKVANKLNKTPGQVLIKWALQRGTSVIPKSSKDERIKENIQVFGWE 276

Query: 1094 L 1096
            +
Sbjct: 277  I 277
to top
>P21300:ALD1_MOUSE Aldose reductase-related protein 1 - Mus musculus (Mouse)|
          Length = 316

 Score = 66.2 bits (160), Expect = 3e-10
 Identities = 68/315 (21%), Positives = 135/315 (42%), Gaps = 18/315 (5%)
 Frame = +2

Query: 230  MGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQSERLLGK 409
            +G GTW           +S   +++E    A+  G    D A  Y        +E  +G+
Sbjct: 16   VGLGTW-----------KSSPGQVKEAVKAAIDAGYRHIDCAYVY-------HNENEVGE 57

Query: 410  FIREC--QGPIKSPDDVVIATKFAAYPWRLTSGQFVNACRSSLERLQIDRLGIGQLHWST 583
             I+E   +  +K  D  +++  +A +           A +++L  L++D L +  +HW  
Sbjct: 58   AIQEKIKENAVKREDLFIVSKLWATF---FEKSLVKKAFQNTLSDLKLDYLDLYLVHWPQ 114

Query: 584  ANYA-----PLQERA-----------LWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSYL 715
               A     P   +             W+ + E+ D+GLV+A+G+SN+   Q+ ++ +  
Sbjct: 115  GFQAGNALLPKDNKGKVLLSKSTFLDAWEAMEELVDQGLVKALGISNFNHFQIERLLNKP 174

Query: 716  ASRGVPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGMLTGKYDASNLPNG 895
              +  P+++       L+    Q +L   C S G+ + AYSPLG             P+ 
Sbjct: 175  GLKHKPVTNQIESHPYLT----QEKLIQYCQSKGIAVTAYSPLG------------SPDR 218

Query: 896  PRSVLFRQILPGLESLLSCLKSIADRKGKTMSQVAINWCICKGAIPIPGVKTVRHVEDNL 1075
            P +     ++  +      +K IA +  KT++QV I + + +  + IP   T   +++NL
Sbjct: 219  PYAKPEDPVVMEIPK----IKEIAAKHKKTVAQVLIRFHVQRNVVVIPKSVTPSRIQENL 274

Query: 1076 GALGWRLSPGEISEL 1120
                ++LS  +++ +
Sbjct: 275  QVFDFQLSEEDMAAI 289
to top
>Q9JII6:AK1A1_MOUSE Alcohol dehydrogenase [NADP+] - Mus musculus (Mouse)|
          Length = 325

 Score = 65.9 bits (159), Expect = 4e-10
 Identities = 71/319 (22%), Positives = 128/319 (40%), Gaps = 20/319 (6%)
 Frame = +2

Query: 230  MGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQSERLLGK 409
            +G GTW           +S   +++     AL  G    D A  YG       +E  +G+
Sbjct: 17   IGLGTW-----------KSEPGQVKAAIKHALSAGYRHIDCASVYG-------NETEIGE 58

Query: 410  FIRECQGPIKSPDDVVIATKFAAYPWRLTSGQFVNACRSSLERLQIDRLGIGQLHW---- 577
             ++E  G  K+     +      +  +        A R +L  LQ++ L +  +HW    
Sbjct: 59   ALKESVGSGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAF 118

Query: 578  ------------STANYAPLQERALWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSYLAS 721
                         T  Y     +  W  L  +  KGLV+A+G+SN+  +Q+  +      
Sbjct: 119  ERGDNPFPKNADGTVRYDSTHYKETWKALEVLVAKGLVKALGLSNFNSRQIDDV------ 172

Query: 722  RGVPLSSAQVQFSLLSMG----EEQMELKTVCDSLGVRLIAYSPLGLGMLTGKYDASNLP 889
                LS A V+ ++L +       Q EL   C + G+ + AYSPLG      ++     P
Sbjct: 173  ----LSVASVRPAVLQVECHPYLAQNELIAHCHARGLEVTAYSPLGSSDRAWRH-----P 223

Query: 890  NGPRSVLFRQILPGLESLLSCLKSIADRKGKTMSQVAINWCICKGAIPIPGVKTVRHVED 1069
            + P  VL  +           + ++A++ G++ +Q+ + W + +  I IP       +  
Sbjct: 224  DEP--VLLEE---------PVVLALAEKHGRSPAQILLRWQVQRKVICIPKSINPSRILQ 272

Query: 1070 NLGALGWRLSPGEISELEA 1126
            N+    +  SP E+ +L+A
Sbjct: 273  NIQVFDFTFSPEEMKQLDA 291
to top
>P14550:AK1A1_HUMAN Alcohol dehydrogenase [NADP+] - Homo sapiens (Human)|
          Length = 325

 Score = 65.9 bits (159), Expect = 4e-10
 Identities = 75/319 (23%), Positives = 128/319 (40%), Gaps = 20/319 (6%)
 Frame = +2

Query: 230  MGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQSERLLGK 409
            +G GTW           +S   +++     AL  G    D A  YG       +E  +G+
Sbjct: 17   IGLGTW-----------KSEPGQVKAAVKYALSVGYRHIDCAAIYG-------NEPEIGE 58

Query: 410  FIRECQGPIKSPDDVVIATKFAAYPWRLTSGQFVNACRSSLERLQIDRLGIGQLHW---- 577
             ++E  GP K+     +      +  +        A R +L  LQ++ L +  +HW    
Sbjct: 59   ALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAF 118

Query: 578  ------------STANYAPLQERALWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSYLAS 721
                         T  Y     +  W  L  +  KGLV+A+G+SN+  +Q+  I      
Sbjct: 119  ERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDI------ 172

Query: 722  RGVPLSSAQVQFSLLSMG----EEQMELKTVCDSLGVRLIAYSPLGLGMLTGKYDASNLP 889
                LS A V+ ++L +       Q EL   C + G+ + AYSPLG         A   P
Sbjct: 173  ----LSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLG-----SSDRAWRDP 223

Query: 890  NGPRSVLFRQILPGLESLLSCLKSIADRKGKTMSQVAINWCICKGAIPIPGVKTVRHVED 1069
            + P  VL  +           + ++A++ G++ +Q+ + W + +  I IP   T   +  
Sbjct: 224  DEP--VLLEE---------PVVLALAEKYGRSPAQILLRWQVQRKVICIPKSITPSRILQ 272

Query: 1070 NLGALGWRLSPGEISELEA 1126
            N+    +  SP E+ +L A
Sbjct: 273  NIKVFDFTFSPEEMKQLNA 291
to top
>Q02895:YP088_YEAST Putative aryl-alcohol dehydrogenase YPL088W - Saccharomyces|
            cerevisiae (Baker's yeast)
          Length = 342

 Score = 65.5 bits (158), Expect = 5e-10
 Identities = 81/340 (23%), Positives = 149/340 (43%), Gaps = 32/340 (9%)
 Frame = +2

Query: 200  VNVGPLSVSPMGFGTWAWGNQLLWGYEESMD--SELQECFNLALKNGINLFDTADSYGTG 373
            + + P+ +  M +G+  W +   W  E+       ++ C++     G+  FDTAD Y   
Sbjct: 14   LKISPIVIGCMSYGSKKWAD---WVIEDKTQIFKIMKHCYD----KGLRTFDTADFYS-- 64

Query: 374  KLNGQSERLLGKFIRECQGPIKSPDDVVIATKF-----------------------AAYP 484
              NG SER++ +F+      IK  + VVI TK                         +  
Sbjct: 65   --NGLSERIIKEFLEYYS--IKR-ETVVIMTKIYFPVDETLDLHHNFTLNEFEELDLSNQ 119

Query: 485  WRLTSGQFVNACRSSLERL--QIDRLGIGQLHWSTANYAPLQERALWDGLVEMYDKGLVR 658
              L+    +    +S++RL   ID L I +L   T    P++E  +   L ++ + G VR
Sbjct: 120  RGLSRKHIIAGVENSVKRLGTYIDLLQIHRLDHET----PMKE--IMKALNDVVEAGHVR 173

Query: 659  AVGVSNYGPKQLLKIHSYLASRG-VPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAY 835
             +G S+    +  ++       G     S+Q  ++LL   E++ EL        + L+ +
Sbjct: 174  YIGASSMLATEFAELQFTADKYGWFQFISSQSYYNLLYR-EDERELIPFAKRHNIGLLPW 232

Query: 836  SPLGLGMLTGKYDAS--NLPNGP--RSVLFRQILPGLESLLSCLKSIADRKGKTMSQVAI 1003
            SP   GMLT   + S   + + P  +S+    +    + +++ ++ ++  K  +M+ ++I
Sbjct: 233  SPNARGMLTRPLNQSTDRIKSDPTFKSLHLDNLEEEQKEIINRVEKVSKDKKVSMAMLSI 292

Query: 1004 NWCICKGAIPIPGVKTVRHVEDNLGALGWRLSPGEISELE 1123
             W + KG  PI G+ T   V++ + AL   L+  EI  LE
Sbjct: 293  AWVLHKGCHPIVGLNTTARVDEAIAALQVTLTEEEIKYLE 332
to top
>P15339:DKGB_CORSS 2,5-diketo-D-gluconic acid reductase B - Corynebacterium sp. (strain|
            SHS752001)
          Length = 277

 Score = 65.5 bits (158), Expect = 5e-10
 Identities = 66/268 (24%), Positives = 117/268 (43%), Gaps = 1/268 (0%)
 Frame = +2

Query: 320  ALKNGINLFDTADSYGTGKLNGQSERLLGKFIRECQGPIKSPDDVVIATKFAAYPWRLTS 499
            A+ +G  L DTA +Y       ++E  +G+ +R         D++++A+K    P R   
Sbjct: 37   AIDSGYRLLDTAVNY-------ENESEVGRAVRASS---VDRDELIVASKI---PGRQHG 83

Query: 500  -GQFVNACRSSLERLQIDRLGIGQLHWSTANYAPLQERALWDGLVEMYDKGLVRAVGVSN 676
              + V++ R SL+RL +D + +  +HW   +     +   W G+++  + GLVR++GVSN
Sbjct: 84   RAEAVDSIRGSLDRLGLDVIDLQLIHWPNPSVGRWLDT--WRGMIDAREAGLVRSIGVSN 141

Query: 677  YGPKQLLKIHSYLASRGVPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGM 856
            +    L    + +   GV  +  QV+   L     Q  L+   D  G+R  ++SPL    
Sbjct: 142  FTEPML---KTLIDETGVTPAVNQVE---LHPYFPQAALRAFHDEHGIRTESWSPL---- 191

Query: 857  LTGKYDASNLPNGPRSVLFRQILPGLESLLSCLKSIADRKGKTMSQVAINWCICKGAIPI 1036
                          RS L  + L         L+ +A   G T +QV + W +  G+ PI
Sbjct: 192  ------------ARRSELLTEQL---------LQELAVVYGVTPTQVVLRWHVQLGSTPI 230

Query: 1037 PGVKTVRHVEDNLGALGWRLSPGEISEL 1120
            P         +N    G+ L+  ++  +
Sbjct: 231  PKSADPDRQRENADVFGFALTADQVDAI 258
to top
>O08782:ALD2_CRIGR Aldose reductase-related protein 2 - Cricetulus griseus (Chinese|
            hamster)
          Length = 316

 Score = 65.5 bits (158), Expect = 5e-10
 Identities = 76/317 (23%), Positives = 133/317 (41%), Gaps = 20/317 (6%)
 Frame = +2

Query: 230  MGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQS--ERLL 403
            +G GTW           +S   +++E   +A+  G    D A +Y      G++  E++ 
Sbjct: 16   VGLGTW-----------QSPPGQVKEAVKVAIDAGYRHIDCAYAYYNEHEVGEAIQEKIK 64

Query: 404  GKFIRECQGPIKSPDDVVIATKFAAYPWRLTSGQFVNACRSSLERLQIDRLGIGQLHWST 583
             K +R         +D+ I +K   +P          A + +L  L++D L +  +HW  
Sbjct: 65   EKAVRR--------EDLFIVSKL--WPTCFERKLLKEAFQKTLTDLKLDYLDLYLIHWPQ 114

Query: 584  A-----NYAPLQERA-----------LWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSYL 715
                     P  ++             W+ + E+ D+GLV+A+GVSN+   Q+ +I +  
Sbjct: 115  GLQPGKELFPKDDQGNVLTSKITFLDAWEVMEELVDEGLVKALGVSNFNHFQIERILNKP 174

Query: 716  ASRGVPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGMLTGKYDASNLPNG 895
              +  P+++       L+    Q +L   C S G+ + AYSPLG             PN 
Sbjct: 175  GLKHKPVTNQVECHPYLT----QEKLIEYCHSKGITVTAYSPLG------------SPNR 218

Query: 896  PRSVLFRQILPGLESLLS--CLKSIADRKGKTMSQVAINWCICKGAIPIPGVKTVRHVED 1069
            P +       P   SLL    +K IA +  KT +QV I + I +  + IP   T   + +
Sbjct: 219  PWA------KPEDPSLLEDPKIKEIAAKHKKTSAQVLIRFHIQRNVVVIPKSVTPARIHE 272

Query: 1070 NLGALGWRLSPGEISEL 1120
            N     ++LS  E++ +
Sbjct: 273  NFQVFDFQLSDQEMATI 289
to top
>O60218:AK1BA_HUMAN Aldo-keto reductase family 1 member B10 - Homo sapiens (Human)|
          Length = 316

 Score = 65.1 bits (157), Expect = 6e-10
 Identities = 78/316 (24%), Positives = 135/316 (42%), Gaps = 19/316 (6%)
 Frame = +2

Query: 230  MGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQSERLLGK 409
            +G GTW           +S   +++E   +A+  G    D A  Y       Q+E  +G+
Sbjct: 16   VGLGTW-----------KSPLGKVKEAVKVAIDAGYRHIDCAYVY-------QNEHEVGE 57

Query: 410  FIRE-CQGPIKSPDDVVIATKFAAYPWRLTSGQFVNACRSSLERLQIDRLGIGQLHW--- 577
             I+E  Q      +D+ I +K   +P          A   +L+ L++  L +  +HW   
Sbjct: 58   AIQEKIQEKAVKREDLFIVSKL--WPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQG 115

Query: 578  --STANYAPLQERA-----------LWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSYLA 718
              S  +  P  ++             W+ + E+ D+GLV+A+GVSN+   Q+ K+ +   
Sbjct: 116  FKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPG 175

Query: 719  SRGVPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGMLTGKYDASNLPNGP 898
             +  P+++       L+    Q +L   C S G+ + AYSPLG             P+ P
Sbjct: 176  LKYKPVTNQVECHPYLT----QEKLIQYCHSKGITVTAYSPLG------------SPDRP 219

Query: 899  RSVLFRQILPGLESLLS--CLKSIADRKGKTMSQVAINWCICKGAIPIPGVKTVRHVEDN 1072
             +       P   SLL    +K IA +  KT +QV I + I +  I IP   T   + +N
Sbjct: 220  WA------KPEDPSLLEDPKIKEIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVEN 273

Query: 1073 LGALGWRLSPGEISEL 1120
            +    ++LS  E++ +
Sbjct: 274  IQVFDFKLSDEEMATI 289
to top
>Q3ZCJ2:AK1A1_BOVIN Alcohol dehydrogenase [NADP+] - Bos taurus (Bovine)|
          Length = 325

 Score = 65.1 bits (157), Expect = 6e-10
 Identities = 73/319 (22%), Positives = 127/319 (39%), Gaps = 20/319 (6%)
 Frame = +2

Query: 230  MGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQSERLLGK 409
            +G GTW           +S   +++     AL  G    D A  YG       +E  +G+
Sbjct: 17   IGLGTW-----------KSDPGQVKAAIKYALSVGYRHIDCAAIYG-------NETEIGE 58

Query: 410  FIRECQGPIKSPDDVVIATKFAAYPWRLTSGQFVNACRSSLERLQIDRLGIGQLHW---- 577
             ++E  GP K      +      +  +        A R +L  LQ++ L +  +HW    
Sbjct: 59   ALKENVGPGKLVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAF 118

Query: 578  ------------STANYAPLQERALWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSYLAS 721
                         T  Y     +  W  L  +  KGLVRA+G+SN+  +Q+  +      
Sbjct: 119  ERGDSPFPKNADGTIRYDSTHYKETWRALEALVAKGLVRALGLSNFNSRQIDDV------ 172

Query: 722  RGVPLSSAQVQFSLLSMG----EEQMELKTVCDSLGVRLIAYSPLGLGMLTGKYDASNLP 889
                LS A V+ ++L +       Q EL   C +  + + AYSPLG         A   P
Sbjct: 173  ----LSVASVRPAVLQVECHPYLAQNELIAHCQARNLEVTAYSPLG-----SSDRAWRDP 223

Query: 890  NGPRSVLFRQILPGLESLLSCLKSIADRKGKTMSQVAINWCICKGAIPIPGVKTVRHVED 1069
              P  VL ++           + ++A++ G++ +Q+ + W + +    IP   T   + +
Sbjct: 224  EEP--VLLKE---------PVVLALAEKHGRSPAQILLRWQVQRKVSCIPKSVTPSRILE 272

Query: 1070 NLGALGWRLSPGEISELEA 1126
            N+    +  SP E+ +L+A
Sbjct: 273  NIQVFDFTFSPEEMKQLDA 291
to top
>Q00049:NORA_ASPFL Norsolorinic acid reductase - Aspergillus flavus|
          Length = 388

 Score = 64.7 bits (156), Expect = 8e-10
 Identities = 78/325 (24%), Positives = 150/325 (46%), Gaps = 22/325 (6%)
 Frame = +2

Query: 221  VSPMGFGTWAWGNQLLWGYEESM-DSELQECFNLA---LKNGINLFDTADSYGTGKLNGQ 388
            VSP+  GT ++GN    G++  M + +    FN+     ++G N  D A+ Y      G 
Sbjct: 27   VSPLCLGTMSFGN----GWKGVMGECDQATSFNMLDTFYESGGNFIDVANFYQ----GGD 78

Query: 389  SERLLGKFIRECQGPIKSPDDVVIATKFAAY-----PWRLTSGQFVNACRS-------SL 532
            +ER +G+++ + Q    + D++V++TK+        P ++ S    N  +S       SL
Sbjct: 79   TERWVGEWMAQRQ----NRDEIVLSTKYTMGYTMFGPQKIKSNYQGNHAKSLRLSVKASL 134

Query: 533  ERLQIDRLGIGQLH-WSTANYAPLQERALWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHS 709
            ++LQ D + +  +H W          R+L      +   G V  +GVS+     ++K ++
Sbjct: 135  QKLQTDYIDLLYVHMWDFTTSVEEVMRSL----NHLVANGKVLYLGVSDTPAWLVVKCNA 190

Query: 710  YLASRGV-PLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGMLTG--KYDAS 880
            +  + G+ P S  Q  +S  +  + + ++  +C+S G+ L  +  LG G      ++   
Sbjct: 191  FARANGLTPFSVYQGHWSC-AFRDFERDILPMCESEGMGLAPWGVLGRGQFRSAEEFSRE 249

Query: 881  NLPNGPRSVLFRQILPGLESLLSCLKSIADRKGKTMSQVAINWCICKG--AIPIPGVKTV 1054
                GP+    R++   L+ +       A +K    + +A  + + K     P+ G + V
Sbjct: 250  GRKMGPQDEKHRRLGEKLDQM-------AQQKNTKATSIAQAYVMHKAPYVFPVIGGRKV 302

Query: 1055 RHVEDNLGALGWRLSPGEISELEAA 1129
             H+++N+ ALG  LS  EI E++ A
Sbjct: 303  EHLKENIEALGLVLSEEEIREIDDA 327
to top
>Q00258:NORA_ASPPA Norsolorinic acid reductase - Aspergillus parasiticus|
          Length = 388

 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 78/325 (24%), Positives = 150/325 (46%), Gaps = 22/325 (6%)
 Frame = +2

Query: 221  VSPMGFGTWAWGNQLLWGYEESM-DSELQECFNLA---LKNGINLFDTADSYGTGKLNGQ 388
            VSP+  GT ++GN    G++  M + +    FN+     ++G N  D A+ Y      G 
Sbjct: 27   VSPLCLGTMSFGN----GWKGVMGECDQATSFNMLDTFYESGGNFIDVANFYQ----GGD 78

Query: 389  SERLLGKFIRECQGPIKSPDDVVIATKFAAY-----PWRLTSGQFVNACRS-------SL 532
            +ER +G+++ + Q    + D++V++TK+        P ++ S    N  +S       SL
Sbjct: 79   TERWVGEWMAQRQ----NRDEIVLSTKYTMGYTMFGPQKIKSNFQGNHAKSLRLSVKASL 134

Query: 533  ERLQIDRLGIGQLH-WSTANYAPLQERALWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHS 709
            ++LQ D + +  +H W          R+L      +   G V  +GVS+     ++K ++
Sbjct: 135  QKLQTDYIDLLYVHMWDFTTSVEEVMRSL----NHLVANGKVLYLGVSDTPAWLVVKCNA 190

Query: 710  YLASRGV-PLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGMLTG--KYDAS 880
            +  + G+ P S  Q  +S  +  + + ++  +C+S G+ L  +  LG G      ++   
Sbjct: 191  FARANGLTPFSVYQGHWSS-AFRDFERDILPMCESEGMGLAPWGVLGRGQFRSAEEFSRE 249

Query: 881  NLPNGPRSVLFRQILPGLESLLSCLKSIADRKGKTMSQVAINWCICKG--AIPIPGVKTV 1054
                GP+    R++   L+ +       A +K    + +A  + + K     P+ G + V
Sbjct: 250  GRKMGPQDEKHRRLGEKLDQM-------AQQKNTKATSIAQAYVMHKAPYVFPVIGGRKV 302

Query: 1055 RHVEDNLGALGWRLSPGEISELEAA 1129
             H+++N+ ALG  LS  EI E++ A
Sbjct: 303  EHLKENIEALGLVLSEEEIREIDDA 327
to top
>P05980:PGFS1_BOVIN Prostaglandin-F synthase 1 - Bos taurus (Bovine)|
          Length = 323

 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 80/329 (24%), Positives = 139/329 (42%), Gaps = 20/329 (6%)
 Frame = +2

Query: 197  KVNVGPLSVSPMGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGK 376
            K+N G   +  +GFGT+A         EE   SE  E    A++ G    D+A  Y    
Sbjct: 9    KLNDGHF-IPVLGFGTYA--------PEEVPKSEALEATKFAIEVGFRHVDSAHLY---- 55

Query: 377  LNGQSERLLGKFIRE--CQGPIKSPDDVVIATKFAAYPW--RLTSGQFVNACRSSLERLQ 544
               Q+E  +G+ IR     G +K  +D+   +K     W   L       A   SL+ LQ
Sbjct: 56   ---QNEEQVGQAIRSKIADGTVKR-EDIFYTSKL----WCNSLQPELVRPALEKSLQNLQ 107

Query: 545  IDRLGIGQLHWSTA-----NYAPLQERA-----------LWDGLVEMYDKGLVRAVGVSN 676
            +D + +  +H   +      + P  E              W+ L +  D GL +++GVSN
Sbjct: 108  LDYVDLYIIHSPVSLKPGNKFVPKDESGKLIFDSVDLCHTWEALEKCKDAGLTKSIGVSN 167

Query: 677  YGPKQLLKIHSYLASRGVPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGM 856
            +  KQL KI +    +  P+ +       L+    Q +L   C S  + L+AY+ LG  +
Sbjct: 168  FNHKQLEKILNKPGLKYKPVCNQVECHPYLN----QSKLLEFCKSHDIVLVAYAALGAQL 223

Query: 857  LTGKYDASNLPNGPRSVLFRQILPGLESLLSCLKSIADRKGKTMSQVAINWCICKGAIPI 1036
            L      S   N    VL       LE  + C  +IA +  +T + VA+ + + +G + +
Sbjct: 224  L------SEWVNSNNPVL-------LEDPVLC--AIAKKHKQTPALVALRYQVQRGVVVL 268

Query: 1037 PGVKTVRHVEDNLGALGWRLSPGEISELE 1123
                  + +++N+    + L+P ++  ++
Sbjct: 269  AKSFNKKRIKENMQVFDFELTPEDMKAID 297
to top
>P52897:PGFS2_BOVIN Prostaglandin-F synthase 2 - Bos taurus (Bovine)|
          Length = 323

 Score = 62.8 bits (151), Expect = 3e-09
 Identities = 77/318 (24%), Positives = 134/318 (42%), Gaps = 20/318 (6%)
 Frame = +2

Query: 230  MGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQSERLLGK 409
            +GFGT+A         EE   SE  E    A++ G    D+A  Y       Q+E  +G+
Sbjct: 19   LGFGTYA--------PEEVPKSEALEATKFAIEVGFRHVDSAHLY-------QNEEQVGQ 63

Query: 410  FIRE--CQGPIKSPDDVVIATKFAAYPW--RLTSGQFVNACRSSLERLQIDRLGIGQLHW 577
             IR     G +K  +D+   +K     W   L       A   SL+ LQ+D + +  +H 
Sbjct: 64   AIRSKIADGTVKR-EDIFYTSKL----WCNSLQPELVRPALEKSLQNLQLDYVDLYIIHS 118

Query: 578  STA-----NYAPLQERA-----------LWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHS 709
              +      + P  E              W+ L +  D GL +++GVSN+  KQL KI +
Sbjct: 119  PVSLKPGNKFVPKDESGKLIFDSVDLCHTWEALEKCKDAGLTKSIGVSNFNHKQLEKILN 178

Query: 710  YLASRGVPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGMLTGKYDASNLP 889
                +  P+ +       L+    Q +L   C S  + L+AY+ LG  +L      S   
Sbjct: 179  KPGLKYKPVCNQVECHPYLN----QSKLLEFCKSHDIVLVAYAALGAQLL------SEWV 228

Query: 890  NGPRSVLFRQILPGLESLLSCLKSIADRKGKTMSQVAINWCICKGAIPIPGVKTVRHVED 1069
            N    VL       LE  + C  +IA +  +T + VA+ + + +G + +      + +++
Sbjct: 229  NSNNPVL-------LEDPVLC--AIAKKHKQTPALVALRYQVQRGVVVLAKSFNKKRIKE 279

Query: 1070 NLGALGWRLSPGEISELE 1123
            N+    + L+P ++  ++
Sbjct: 280  NMQVFDFELTPEDMKAID 297
to top
>P22045:P100_LEIMA Probable reductase - Leishmania major|
          Length = 284

 Score = 62.8 bits (151), Expect = 3e-09
 Identities = 68/281 (24%), Positives = 109/281 (38%), Gaps = 6/281 (2%)
 Frame = +2

Query: 302  QECFNLALKNGINLFDTADSYGTGKLNGQSERLLGKFIRECQGPIKSPDDVVIATKFAAY 481
            +   N AL  G    DTA  Y       ++E  +G  +R    P    +DV I TK    
Sbjct: 34   ENAVNWALCAGYRHIDTAAIY-------KNEESVGAGLRASGVP---REDVFITTKL--- 80

Query: 482  PWRLTSG--QFVNACRSSLERLQIDRLGIGQLHWSTANYAPLQERAL----WDGLVEMYD 643
             W    G    + A   S ++L +D + +  +HW        +E       W    ++Y 
Sbjct: 81   -WNTEQGYESTLAAFEESRQKLGVDYIDLYLIHWPRGKDILSKEGKKYLDSWRAFEQLYK 139

Query: 644  KGLVRAVGVSNYGPKQLLKIHSYLASRGVPLSSAQVQFSLLSMGEEQMELKTVCDSLGVR 823
            +  VRA+GVSN+    +  +   LA   V     QV+   L+    Q +L+  CD+  ++
Sbjct: 140  EKKVRAIGVSNF---HIHHLEDVLAMCTVTPMVNQVELHPLN---NQADLRAFCDAKQIK 193

Query: 824  LIAYSPLGLGMLTGKYDASNLPNGPRSVLFRQILPGLESLLSCLKSIADRKGKTMSQVAI 1003
            + A+SPLG G L                               L +I  +  KT +QV +
Sbjct: 194  VEAWSPLGQGKLLSN--------------------------PILSAIGAKYNKTAAQVIL 227

Query: 1004 NWCICKGAIPIPGVKTVRHVEDNLGALGWRLSPGEISELEA 1126
             W I K  I IP       +E+N     + L   ++  ++A
Sbjct: 228  RWNIQKNLITIPKSVHRERIEENADIFDFELGAEDVMSIDA 268
to top
>Q96JD6:AKCL2_HUMAN Aldo-keto reductase family 1 member C-like protein 2 - Homo sapiens|
            (Human)
          Length = 320

 Score = 62.4 bits (150), Expect = 4e-09
 Identities = 75/313 (23%), Positives = 131/313 (41%), Gaps = 38/313 (12%)
 Frame = +2

Query: 296  ELQECFNLALKNGINLFDTADSYGTGKLNGQSERLLGKFIREC---QGPIKSPDDVVIAT 466
            ++ E    A+  G   FD A  Y        +ER +G  IR C   +G ++  +D+ IAT
Sbjct: 18   KVTEAVKEAIDAGYRHFDCAYFY-------HNEREVGAGIR-CKIKEGAVRR-EDLFIAT 68

Query: 467  KFAAYPWRLTSGQFVNACRSSLERLQIDRLGIGQLHW---------------STANYA-- 595
            K      + +  +   ACR SL+ L+++ L +  +HW               S  ++   
Sbjct: 69   KLWCTCHKKSLVE--TACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSFCLS 126

Query: 596  -------PLQERAL-----------WDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSYLAS 721
                   PL E  +           W+ + ++   GLV+ +GVSN+  +QL ++ +    
Sbjct: 127  HPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGL 186

Query: 722  RGVPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGMLTGKYDASNLPNGPR 901
            R  PL++       L+    Q  L + C S  V + AY PLG     G  +  +L + P 
Sbjct: 187  RFKPLTNQIECHPYLT----QKNLISFCQSRDVSVTAYRPLG-----GSCEGVDLIDNP- 236

Query: 902  SVLFRQILPGLESLLSCLKSIADRKGKTMSQVAINWCICKGAIPIPGVKTVRHVEDNLGA 1081
                             +K IA   GK+ +Q+ I + I +  I IPG  T  H+++N+  
Sbjct: 237  ----------------VIKRIAKEHGKSPAQILIRFQIQRNVIVIPGSITPSHIKENIQV 280

Query: 1082 LGWRLSPGEISEL 1120
              + L+  ++  +
Sbjct: 281  FDFELTQHDMDNI 293
to top
>Q9P8R5:XYL1_ASPNG NAD(P)H-dependent D-xylose reductase - Aspergillus niger|
          Length = 319

 Score = 62.0 bits (149), Expect = 5e-09
 Identities = 78/335 (23%), Positives = 129/335 (38%), Gaps = 24/335 (7%)
 Frame = +2

Query: 188  PWEKVNVGPLSVSPMGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYG 367
            P  K+N G   +  +GFG W   N          D+   + ++ A+K G  LFD A  YG
Sbjct: 4    PTVKLNSG-YDMPLVGFGLWKVNN----------DTCADQIYH-AIKEGYRLFDGACDYG 51

Query: 368  TGKLNGQSERLLGKFIRECQGPIKSPDDVVIATKFAAYPWRLTSGQFVNACRSSLERLQI 547
                 GQ    + + I++  G +K  +  +++  + ++       +    CR  L    I
Sbjct: 52   NEVEAGQG---IARAIKD--GLVKREELFIVSKLWNSFH---DGDRVEPICRKQLADWGI 103

Query: 548  DRLGIGQLHW--------STANYAP---------------LQERALWDGLVEMYDKGLVR 658
            D   +  +H+            Y P               +QE   W  +  + DK L R
Sbjct: 104  DYFDLYIVHFPISLKYVDPAVRYPPGWKSEKDELEFGNATIQE--TWTAMESLVDKKLAR 161

Query: 659  AVGVSNYGPKQLLKIHSYLASRGVPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYS 838
            ++G+SN+  + ++ +  Y   R   L      +        Q  L       G+ + AYS
Sbjct: 162  SIGISNFSAQLVMDLLRYARIRPATLQIEHHPYL------TQTRLVEYAQKEGLTVTAYS 215

Query: 839  PLG-LGMLTGKYDASNLPNGPRSVLFRQILPGLESLLSCLKSIADRKGKTMSQVAINWCI 1015
              G L  L  +    N  + P   LF   L         +KSIA++ G+T +QV + W  
Sbjct: 216  SFGPLSFL--ELSVQNAVDSP--PLFEHQL---------VKSIAEKHGRTPAQVLLRWAT 262

Query: 1016 CKGAIPIPGVKTVRHVEDNLGALGWRLSPGEISEL 1120
             +G   IP     + ++ NL   GW L   EI  +
Sbjct: 263  QRGIAVIPKSNNPQRLKQNLDVTGWNLEEEEIKAI 297
to top
>Q8ZI40:DKGA_YERPE 2,5-diketo-D-gluconic acid reductase A - Yersinia pestis|
          Length = 277

 Score = 61.2 bits (147), Expect = 9e-09
 Identities = 67/300 (22%), Positives = 128/300 (42%), Gaps = 2/300 (0%)
 Frame = +2

Query: 260  QLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQSERLLGKFIRECQGPIK 439
            QL  G  ++   E +   + AL+ G    DTA  Y       ++E  +GK ++       
Sbjct: 17   QLGLGVWQASIQETELAVSKALEVGYRSIDTAAIY-------KNEEGVGKALKAAA---V 66

Query: 440  SPDDVVIATKFAAYPWRLTSGQFVNACRSSLERLQIDRLGIGQLHWSTANYAPLQER--A 613
            + D++ I TK     W         A  +SL++LQ+D + +  +HW      P Q+   +
Sbjct: 67   ARDELFITTKL----WNDDQHNPQQALETSLQKLQLDYVDLYLIHWPD----PKQDHYVS 118

Query: 614  LWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSYLASRGVPLSSAQVQFSLLSMGEEQMEL 793
             W  LV + ++GL+R++GV N+    L ++   +   G+  +  Q++   L    +Q +L
Sbjct: 119  AWRELVTLKEQGLIRSIGVCNFHIPHLQRL---IDETGIAPTVNQIELHPLL---QQRQL 172

Query: 794  KTVCDSLGVRLIAYSPLGLGMLTGKYDASNLPNGPRSVLFRQILPGLESLLSCLKSIADR 973
                 +  +   ++SPL                G + V  ++I          ++ +A +
Sbjct: 173  HAWNATHHIATESWSPLA--------------QGGKGVFDQEI----------IRKLAQQ 208

Query: 974  KGKTMSQVAINWCICKGAIPIPGVKTVRHVEDNLGALGWRLSPGEISELEAAAMECPKKM 1153
              KT +Q+ I W +  G I IP   T   + +N     ++L   E+  L    ++C K++
Sbjct: 209  YNKTPAQIVIRWHLDSGLIVIPKSVTPARIRENFEVFDFKLQKEEL--LAITKLDCGKRL 266
to top
>Q06494:PLR1_YEAST Putative pyridoxal reductase - Saccharomyces cerevisiae (Baker's|
            yeast)
          Length = 345

 Score = 60.8 bits (146), Expect = 1e-08
 Identities = 66/256 (25%), Positives = 115/256 (44%), Gaps = 28/256 (10%)
 Frame = +2

Query: 437  KSPD---DVVIATKFAAYPWRLTS----GQFVNACRSSLERL--QIDRLGIGQLHWSTAN 589
            K PD   DVVI+ K  A    LT        V + ++S+  +   ID   + ++  S   
Sbjct: 76   KYPDLRKDVVISCKGGADNATLTPRGSHDDVVQSVKNSVSAIGGYIDIFEVARIDTSLCT 135

Query: 590  YAPLQERALWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSYLASRGVPLSSAQVQFSLLS 769
               +     ++ L EM  +G++  + +S    +Q+  IH      G  L+  +V+ SL S
Sbjct: 136  KGEVYPYESFEALAEMISEGVIGGISLSEVNEEQIRAIHK---DWGKFLTCVEVELSLFS 192

Query: 770  MGEEQMELKTVCDSLGVRLIAYSPLGLGMLTGKYDA-SNLPNGP-RSVLFRQILPGLESL 943
                   +   C  LG+ +I YSPLG G+LTG+  + +++P G  R  L R     L+  
Sbjct: 193  NDILHNGIAKTCAELGLSIICYSPLGRGLLTGQLKSNADIPEGDFRKSLKRFSDESLKKN 252

Query: 944  LSCLK----SIADRKGK----TMSQVAINWC-------ICKGA--IPIPGVKTVRHVEDN 1072
            L+ ++     I D++ +    T++Q+A+ W           GA  IPIP   ++  V +N
Sbjct: 253  LTLVRFLQEEIVDKRPQNNSITLAQLALGWVKHWNKVPEYSGAKFIPIPSGSSISKVNEN 312

Query: 1073 LGALGWRLSPGEISEL 1120
                  +L+  E + +
Sbjct: 313  FDEQKTKLTDQEFNAI 328
to top
>Q9DCT1:AK1E1_MOUSE Aldo-keto reductase family 1 member E1 - Mus musculus (Mouse)|
          Length = 301

 Score = 60.8 bits (146), Expect = 1e-08
 Identities = 69/317 (21%), Positives = 127/317 (40%), Gaps = 16/317 (5%)
 Frame = +2

Query: 218  SVSPMGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQSER 397
            ++  +G GTW           ++   E+ +   LA+  G   FD A  Y     + +SE 
Sbjct: 3    NIPTVGLGTW-----------KASPGEVTDAVKLAINLGYRHFDCAYLY-----HNESEV 46

Query: 398  LLGKFIRECQGPIKSPDDVVIATKFAAYPWRLTSGQFVNACRSSLERLQIDRLGIGQLHW 577
             +G   +  +G +K  D  V++  +     +        AC ++LE L +D L +  +HW
Sbjct: 47   GMGISEKIKEGVVKREDLFVVSKLWCTCHKK---SLVKTACTNTLEALNLDYLDLYLIHW 103

Query: 578  STA-----NYAPLQERA-----------LWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHS 709
                       PL                W+ + ++  +GLV+ +GVSN+  +QL ++  
Sbjct: 104  PMGFKPGEKDIPLDRNGKVIPSHTSFLDTWEAMEDLVFEGLVKNLGVSNFNHEQLERLLD 163

Query: 710  YLASRGVPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGMLTGKYDASNLP 889
                R  P+++       L+    Q +L   C    V + AY PLG     G     +L 
Sbjct: 164  KPGLRVRPITNQIECHPYLN----QKKLIDFCHKRNVSVTAYRPLG-----GSGGGFHLM 214

Query: 890  NGPRSVLFRQILPGLESLLSCLKSIADRKGKTMSQVAINWCICKGAIPIPGVKTVRHVED 1069
            +                  + ++ IA + GK+ +Q+ I + I +  I IP   T   + +
Sbjct: 215  DD-----------------TVIRKIAKKHGKSPAQILIRFQIQRNLIVIPKSVTPSRIRE 257

Query: 1070 NLGALGWRLSPGEISEL 1120
            N+    + L+  ++ EL
Sbjct: 258  NIQVFDFELTEKDMEEL 274
to top
>P70694:DHB5_MOUSE Estradiol 17 beta-dehydrogenase 5 - Mus musculus (Mouse)|
          Length = 323

 Score = 60.5 bits (145), Expect = 2e-08
 Identities = 71/319 (22%), Positives = 133/319 (41%), Gaps = 21/319 (6%)
 Frame = +2

Query: 230  MGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQSERLLGK 409
            +GFGT+A         +E   S+  E   +A+  G    D+A  Y       Q+E+ +G 
Sbjct: 19   LGFGTYA--------PQEVPKSKATEATKIAIDAGFRHIDSASMY-------QNEKEVGL 63

Query: 410  FIRE--CQGPIKSPDDVVIATKFAAYPWRLTSGQFVNAC-RSSLERLQIDRLGIGQLHWS 580
             IR     G +K  D    +  +  +       + V  C   SL++LQ+D + +  +H+ 
Sbjct: 64   AIRSKIADGTVKREDIFYTSKVWCTFH----RPELVRVCLEQSLKQLQLDYVDLYLIHFP 119

Query: 581  TA-----NYAPLQERA-----------LWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSY 712
             A     NY P  E              W+ + +  D GL +++GVSN+  +QL KI   
Sbjct: 120  MAMKPGENYLPKDENGKLIYDAVDICDTWEAMEKCKDAGLAKSIGVSNFNRRQLEKILKK 179

Query: 713  LASRGVPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGMLTGKYDASN--L 886
               +  P+ +       L+ G    +L   C S  + L+AYS LG        D S+  L
Sbjct: 180  PGLKYKPVCNQVECHPYLNQG----KLLDFCRSKDIVLVAYSALGSHREKQWVDQSSPVL 235

Query: 887  PNGPRSVLFRQILPGLESLLSCLKSIADRKGKTMSQVAINWCICKGAIPIPGVKTVRHVE 1066
             + P                  L S+A +  +T + +A+ + + +G + +    + + ++
Sbjct: 236  LDNP-----------------VLGSMAKKYNRTPALIALRYQLQRGVVVLAKSFSEKRIK 278

Query: 1067 DNLGALGWRLSPGEISELE 1123
            +N+    ++L+  ++  L+
Sbjct: 279  ENMQVFEFQLTSEDMKVLD 297
to top
>Q8CG45:ARK72_RAT Aflatoxin B1 aldehyde reductase member 2 - Rattus norvegicus (Rat)|
          Length = 367

 Score = 60.5 bits (145), Expect = 2e-08
 Identities = 78/304 (25%), Positives = 124/304 (40%), Gaps = 30/304 (9%)
 Frame = +2

Query: 323  LKNGINLFDTADSYGTGKLNGQSERLLGKFIRECQGPIKSPDDVVIATKFAAYPW---RL 493
            L+ G+N  DTA  Y     +GQSE +LG       G       V IATK  A PW    L
Sbjct: 72   LERGLNELDTAFMY----CDGQSESILGSL---GLGLGSGDCTVKIATK--ANPWDGKSL 122

Query: 494  TSGQFVNACRSSLERLQIDRLGIGQLHWSTANYAPLQERALWDGLVEMYDKGLVRAVGVS 673
                  +   +SL+RLQ  R+ +  LH +  +  P+ E        +++ +G    +G+S
Sbjct: 123  KPDSVRSQLETSLKRLQCPRVDLFYLH-APDHGTPIVETL--QACQQLHQEGKFVELGLS 179

Query: 674  NYGPKQLLKIHSYLASRGVPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLG 853
            NY   ++ +I++   S G  L +        +  + + EL       G+R  AY+PL  G
Sbjct: 180  NYASWEVAEIYTLCKSNGWILPTVYQGMYNATTRQVETELLPCLRYFGLRFYAYNPLAGG 239

Query: 854  MLTGKY----DASNLPNGP----------RSVLFRQ-ILPGLESLLSCLKSIADRKGKTM 988
            +LTGKY         P G           R+  +++     +  +   LK+       +M
Sbjct: 240  LLTGKYRYEDKDGKQPEGRFFGNSWSETYRNRFWKEHHFEAIALVEKALKTTYGTSAPSM 299

Query: 989  SQVAINWCI-------CKGAIPIPGVKTVRHVEDNLGAL-GWRLSPGEISELEAA----A 1132
            +  A+ W          +G   I G+ ++  +E NL A     L P  +     A    A
Sbjct: 300  TSAALRWMYHHSQLQGTRGDAVILGMSSLEQLEQNLAATEEGPLEPAVVEAFNQAWNVVA 359

Query: 1133 MECP 1144
             ECP
Sbjct: 360  HECP 363
to top
>P52898:DDBX_BOVIN Dihydrodiol dehydrogenase 3 - Bos taurus (Bovine)|
          Length = 323

 Score = 60.1 bits (144), Expect = 2e-08
 Identities = 79/329 (24%), Positives = 136/329 (41%), Gaps = 20/329 (6%)
 Frame = +2

Query: 197  KVNVGPLSVSPMGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGK 376
            K+N G   +  +GFGT+A          E   SE  E    A++ G    D+A  Y    
Sbjct: 9    KLNDGHF-IPVLGFGTFA--------PREVPKSEALEVTKFAIEAGFRHIDSAHLY---- 55

Query: 377  LNGQSERLLGKFIRE--CQGPIKSPDDVVIATKFAAYPWRLTSGQFVNACRSSLERLQID 550
               Q+E  +G+ IR     G +K  +D+   +K   +   L       A   SL  LQ+D
Sbjct: 56   ---QNEEQVGQAIRSKIADGTVKR-EDIFYTSKL--WSTSLRPELVRPALEKSLNNLQLD 109

Query: 551  RLGIGQLHWSTA------------NYAPLQERA----LWDGLVEMYDKGLVRAVGVSNYG 682
             + +  +H+  A            N  P+ +       W+ L +  D GL +++GVSN+ 
Sbjct: 110  YVDLYIIHFPVALKPGETLFPTDENGKPIFDSVDLCRTWEALEKCKDAGLTKSIGVSNFN 169

Query: 683  PKQLLKIHSYLASRGVPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGMLT 862
             KQL KI +    +  P+ + QV+         Q +L   C S  + L+AY  LG   L 
Sbjct: 170  HKQLEKILNKPGLKYKPVCN-QVECHPYF---NQSKLLDFCKSHDIVLVAYGALGSQRLK 225

Query: 863  GKYDASNLPNGPRSVLFRQILPGLESLLS--CLKSIADRKGKTMSQVAINWCICKGAIPI 1036
                               + P L  LL    L +IA +  +T + VA+ + I +G + +
Sbjct: 226  -----------------EWVNPNLPFLLEDPVLSAIAKKHRQTPALVALRYQIQRGVVVL 268

Query: 1037 PGVKTVRHVEDNLGALGWRLSPGEISELE 1123
                  + +++N+    + L+P ++  ++
Sbjct: 269  AKSYNKKRIKENIQVFDFELTPEDMKAID 297
to top
>P49249:IN22_MAIZE IN2-2 protein - Zea mays (Maize)|
          Length = 306

 Score = 59.7 bits (143), Expect = 3e-08
 Identities = 63/231 (27%), Positives = 108/231 (46%), Gaps = 6/231 (2%)
 Frame = +2

Query: 188 PWEKVNVGPLSVSPMGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYG 367
           P  K+    L VS  G G    G    +G  +  +SE+ +  + A+  G+   DT+D YG
Sbjct: 9   PRIKLGSQGLEVSAQGLG--CMGMSAFYGPPKP-ESEMIKLIHHAVDAGVTFLDTSDVYG 65

Query: 368 TGKLNGQSERLLGKFIRECQGPIKSPDDVVIATKFA---AYPWRLTSGQFV---NACRSS 529
                  +E LLGK +   QG ++  + V +ATKF    A   R   G       AC  S
Sbjct: 66  PHT----NEVLLGKAL---QGGVR--EKVELATKFGVSFADGKREIHGDPAYVRTACEGS 116

Query: 530 LERLQIDRLGIGQLHWSTANYAPLQERALWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHS 709
            +RL +D + +   H       P++       L ++ ++G ++ +G+S      + + H+
Sbjct: 117 FKRLGVDCIDLYYQH-RIDKRVPIEVTI--GELKKLVEEGKIKYIGLSEASASTIRRAHA 173

Query: 710 YLASRGVPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGMLT 862
                  P+++ Q+++SL S   E+  + T C  LG+ ++AYSPLG G  +
Sbjct: 174 VH-----PITAVQLEWSLWSRDAEEDIIPT-CRELGIGIVAYSPLGRGFFS 218
to top
>P54569:YQKF_BACSU Uncharacterized oxidoreductase yqkF - Bacillus subtilis|
          Length = 306

 Score = 59.3 bits (142), Expect = 3e-08
 Identities = 72/325 (22%), Positives = 137/325 (42%), Gaps = 15/325 (4%)
 Frame = +2

Query: 197  KVNVGPLSVSPMGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGK 376
            K+    L +S +G G  + G +          ++     + A++ GIN  DTAD Y    
Sbjct: 5    KLGTSDLDISEVGLGCMSLGTE---------KNKALSILDEAIELGINYLDTADLYD--- 52

Query: 377  LNGQSERLLGKFIRECQGPIKSPDDVVIATKFA--------AYPWRLTSGQFVNACRSSL 532
              G++E ++G  I+  +       D+++ATK           + W  +      A + SL
Sbjct: 53   -RGRNEEIVGDAIQNRR------HDIILATKAGNRWDDGSEGWYWDPSKAYIKEAVKKSL 105

Query: 533  ERLQIDRLGIGQLHWSTANYAPLQERALWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSY 712
             RL+ D + + QLH  T     + E    +   E+  +G++R  G+S+  P     I  Y
Sbjct: 106  TRLKTDYIDLYQLHGGTIE-DNIDETI--EAFEELKQEGVIRYYGISSIRPN---VIKEY 159

Query: 713  LASRGVPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGMLTGK----YDAS 880
            +    +   S  +QFSL     E  E   + +   + ++A  P+  G+LT K       S
Sbjct: 160  VKKSNI--VSIMMQFSLFDRRPE--EWLPLLEEHQISVVARGPVAKGLLTEKPLDQASES 215

Query: 881  NLPNGPRSVLFRQILPGLESLLSCLKSIADRKGKTMSQVAINWCICKGAIP--IPGVKTV 1054
               NG  S  F ++    +++      +      +M++ ++ + + + A+   I G   +
Sbjct: 216  MKQNGYLSYSFEELTNARKAMEEVAPDL------SMTEKSLQYLLAQPAVASVITGASKI 269

Query: 1055 RHVEDNL-GALGWRLSPGEISELEA 1126
              + +N+  A   RL+  EI  L++
Sbjct: 270  EQLRENIQAANARRLTEEEIKALQS 294
to top
>P40690:ALKE_BABBO Aldo-keto reductase - Babesia bovis|
          Length = 285

 Score = 59.3 bits (142), Expect = 3e-08
 Identities = 50/176 (28%), Positives = 77/176 (43%), Gaps = 36/176 (20%)
 Frame = +2

Query: 452 VVIATKFAA----YPW------RLTSGQFVNACRSSLERLQIDRLGIGQLHWSTA----- 586
           VVIATK A+      W      +L+    + A   SL RL  D + + QLHW        
Sbjct: 3   VVIATKVASRSSHLSWLRSGDCKLSKDNILKAVDGSLSRLNTDYIDLLQLHWPDRYVPMN 62

Query: 587 ------------------NYAPLQERALWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSY 712
                             N  PL+++   D L  +  +G +R  G+SN  P   L+ +  
Sbjct: 63  ANGDFHEVFHDTENMIDENSVPLEDQL--DALQTLLTQGKIRHWGLSNETPWGTLRFYKL 120

Query: 713 LASRGVPL-SSAQVQFSLLSMGEEQMELKTVC--DSLGVRLIAYSPLGLGMLTGKY 871
               GV   +S Q+ ++LL   E +     +C   + G+ ++AY+PL  G+LTGKY
Sbjct: 121 AKQAGVAAPASVQLHYNLLCRNEVEKGFVELCRPQNTGIAILAYAPLAGGILTGKY 176
to top
>P25906:YDBC_ECOLI Putative oxidoreductase ydbC - Escherichia coli|
          Length = 286

 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 81/324 (25%), Positives = 128/324 (39%), Gaps = 13/324 (4%)
 Frame = +2

Query: 206  VGPLSVSPMGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNG 385
            +G  SV+ +G+G        ++G        +      AL  G+N  DT+D YG    N 
Sbjct: 8    LGTKSVNRLGYGAMQLAGPGVFGPPRDRHVAIT-VLREALALGVNHIDTSDFYGPHVTN- 65

Query: 386  QSERLLGKFIRECQGPIKSPDDVVIATKFAA-----YPW--RLTSGQFVNACRSSLERLQ 544
                   + IRE   P    DD+ I TK  A       W    +  +   A   +L  L 
Sbjct: 66   -------QIIREALYPYS--DDLTIVTKIGARRGEDASWLPAFSPAELQKAVHDNLRNLG 116

Query: 545  IDRLGIGQLHWSTAN-YAPLQE--RALWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSYL 715
            +D L +  L     + + P +    A    L EM  +GLV+ +G+SN  P Q+ +     
Sbjct: 117  LDVLDVVNLRVMMGDGHGPAEGSIEASLTVLAEMQQQGLVKHIGLSNVTPTQVAE----- 171

Query: 716  ASRGVPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSP-LGLGMLTGKYDASNLPN 892
            A +   +   Q ++++    ++ M      D+L    IAY P   LG  T          
Sbjct: 172  ARKIAEIVCVQNEYNIAHRADDAM-----IDALAHDGIAYVPFFPLGGFT---------- 216

Query: 893  GPRSVLFRQILPGLESLLSCLKSIADRKGKTMSQVAINWCICK--GAIPIPGVKTVRHVE 1066
                         L+S  S L  +A   G T  QVA+ W + +    + IPG  +V H+ 
Sbjct: 217  ------------PLQS--STLSDVAASLGATPMQVALAWLLQRSPNILLIPGTSSVAHLR 262

Query: 1067 DNLGALGWRLSPGEISELEAAAME 1138
            +N+ A    LS   +S L+  + E
Sbjct: 263  ENMAAEKLHLSEEVLSTLDGISRE 286
to top
>P31867:XYL1_PICST NAD(P)H-dependent D-xylose reductase - Pichia stipitis (Yeast)|
          Length = 318

 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 78/337 (23%), Positives = 131/337 (38%), Gaps = 26/337 (7%)
 Frame = +2

Query: 188  PWEKVNVGPLSVSPMGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYG 367
            P  K+N G   +  +GFG W          +  +D+  ++ +  A+K G  LFD A+ Y 
Sbjct: 2    PSIKLNSG-YDMPAVGFGCW----------KVDVDTCSEQIYR-AIKTGYRLFDGAEDYA 49

Query: 368  TGKLNGQSERLLGKFIRECQGPIKSPDDVVIATKFAAYPWRLTSGQFVNACRSSLERLQI 547
              KL G   +   K I E  G +K  D  + +  +  Y           A   +L  LQ+
Sbjct: 50   NEKLVGAGVK---KAIDE--GIVKREDLFLTSKLWNNYHH---PDNVEKALNRTLSDLQV 101

Query: 548  DRLGIGQLHWS-TANYAPLQER---------------------ALWDGLVEMYDKGLVRA 661
            D + +  +H+  T  + PL+E+                       W  L ++   G +R+
Sbjct: 102  DYVDLFLIHFPVTFKFVPLEEKYPPGFYCGKGDNFDYEDVPILETWKALEKLVKAGKIRS 161

Query: 662  VGVSNYGPKQLLKIHSYLASRGVPLSSAQVQFSLLSMGE----EQMELKTVCDSLGVRLI 829
            +GVSN+    LL +          L  A ++ S+L +      +Q  L     S G+ + 
Sbjct: 162  IGVSNFPGALLLDL----------LRGATIKPSVLQVEHHPYLQQPRLIEFAQSRGIAVT 211

Query: 830  AYSPLGLGMLTGKYDASNLPNGPRSVLFRQILPGLESLLSCLKSIADRKGKTMSQVAINW 1009
            AYS  G            L   P   LF             +K+IA + GK+ +QV + W
Sbjct: 212  AYSSFGPQSFVELNQGRALNTSP---LFEN---------ETIKAIAAKHGKSPAQVLLRW 259

Query: 1010 CICKGAIPIPGVKTVRHVEDNLGALGWRLSPGEISEL 1120
               +G   IP   TV  + +N     + L   + +++
Sbjct: 260  SSQRGIAIIPKSNTVPRLLENKDVNSFDLDEQDFADI 296
to top
>Q876L8:XYL1_TRIRE NAD(P)H-dependent D-xylose reductase - Trichoderma reesei (Hypocrea|
            jecorina)
          Length = 324

 Score = 55.5 bits (132), Expect = 5e-07
 Identities = 76/336 (22%), Positives = 138/336 (41%), Gaps = 25/336 (7%)
 Frame = +2

Query: 188  PWEKVNVGPLSVSPMGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYG 367
            P  K+N G   +  +GFG W   N +               +N A+K G  LFD A  YG
Sbjct: 4    PTLKLNSG-YDMPQVGFGLWKVDNAVC----------ADTVYN-AIKAGYRLFDGACDYG 51

Query: 368  TGKLNGQSERLLGKFIRECQGPIKSPDDVVIATKFAAYPWRLTSGQFVNACRSSLERLQI 547
              K  G+    + + I++  G +K  D  +++  +  +       +     R  L   QI
Sbjct: 52   NEKECGEG---VARAIKD--GLVKREDLFIVSKLWQTFH---DEDKVEPITRRQLADWQI 103

Query: 548  DRLGIGQLHWSTA--------NYAP-----------------LQERALWDGLVEMYDKGL 652
            D   +  +H+  A         Y P                 LQ+   W  +  + DKGL
Sbjct: 104  DYFDLFLVHFPAALEYVDPSVRYPPGWFYDGKSEVRWSKTTTLQQ--TWGAMERLVDKGL 161

Query: 653  VRAVGVSNYGPKQLLKIHSYLASRGVPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIA 832
             R++GVSNY   Q   ++  L    +  ++ Q++        +Q +L ++  + G+ + A
Sbjct: 162  ARSIGVSNY---QAQSVYDALIYARIKPATLQIEHHPYL---QQPDLVSLAQTEGIVVTA 215

Query: 833  YSPLGLGMLTGKYDASNLPNGPRSVLFRQILPGLESLLSCLKSIADRKGKTMSQVAINWC 1012
            YS  G    TG  +     + PR+   + + P ++S    +K++AD+  +T +QV + W 
Sbjct: 216  YSSFG---PTGFMEL----DMPRA---KSVAPLMDS--PVIKALADKHRRTPAQVLLRWA 263

Query: 1013 ICKGAIPIPGVKTVRHVEDNLGALGWRLSPGEISEL 1120
              +G   IP       +  NL    + L   +++++
Sbjct: 264  TQRGIAVIPKTSRPEVMAQNLDNTSFDLDSEDLAKI 299
to top
>P87039:XYL2_CANTR NADPH-dependent D-xylose reductase II,III - Candida tropicalis|
            (Yeast)
          Length = 324

 Score = 55.1 bits (131), Expect = 6e-07
 Identities = 72/335 (21%), Positives = 132/335 (39%), Gaps = 24/335 (7%)
 Frame = +2

Query: 188  PWEKVNVGPLSVSPMGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYG 367
            P  K+N G   +  +GFG W   N+          +   + +N A+K G  LFD A+ YG
Sbjct: 8    PTIKLNSG-YEMPLVGFGCWKVNNE----------TAADQIYN-AIKTGYRLFDGAEDYG 55

Query: 368  TGKLNGQSERLLGKFIRECQGPIKSPDDVVIATKFAAYPWRLTSG--QFVNACRSSLERL 541
              K  G+    + + I+E  G +K  +++ I +K     W           A   +L  L
Sbjct: 56   NEKEVGEG---INRAIKE--GLVKR-EELFITSKL----WNNFHDPKNVETALNKTLSDL 105

Query: 542  QIDRLGIGQLHWSTA-NYAPLQERA---------------------LWDGLVEMYDKGLV 655
             +D + +  +H+  A  + P++E+                       W  L ++ + G +
Sbjct: 106  NLDYVDLFLIHFPIAFKFVPIEEKYPPGFYCGDGDNFHYEDVPLLDTWKALEKLVEAGKI 165

Query: 656  RAVGVSNYGPKQLLKIHSYLASRGVPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAY 835
            +++G+SN+    +     Y   RG  +  A +Q        +Q +L       G+ +  Y
Sbjct: 166  KSIGISNFTGALI-----YDLIRGATIKPAVLQIEHHPY-LQQPKLIEYVQKAGIAITGY 219

Query: 836  SPLGLGMLTGKYDASNLPNGPRSVLFRQILPGLESLLSCLKSIADRKGKTMSQVAINWCI 1015
            S  G      + ++    N P   LF             +KSIAD+ GK+ +QV + W  
Sbjct: 220  SSFGPQSFL-ELESKRALNTP--TLFEH---------ETIKSIADKHGKSPAQVLLRWAT 267

Query: 1016 CKGAIPIPGVKTVRHVEDNLGALGWRLSPGEISEL 1120
             +    IP       +  NL  + + L+  ++  +
Sbjct: 268  QRNIAVIPKSNNPERLAQNLSVVDFDLTKDDLDNI 302
to top
>Q8CG76:ARK72_MOUSE Aflatoxin B1 aldehyde reductase member 2 - Mus musculus (Mouse)|
          Length = 367

 Score = 55.1 bits (131), Expect = 6e-07
 Identities = 75/304 (24%), Positives = 123/304 (40%), Gaps = 30/304 (9%)
 Frame = +2

Query: 323  LKNGINLFDTADSYGTGKLNGQSERLLGKFIRECQGPIKSPDDVVIATKFAAYPWR---L 493
            L+ G +  DTA  Y     +GQSE +LG       G       V IATK  A PW    L
Sbjct: 72   LERGHSELDTAFMY----CDGQSENILGGL---GLGLGSGDCTVKIATK--ANPWEGKSL 122

Query: 494  TSGQFVNACRSSLERLQIDRLGIGQLHWSTANYAPLQERALWDGLVEMYDKGLVRAVGVS 673
                  +   +SL+RLQ  R+ +  LH +  +  P++E        +++ +G    +G+S
Sbjct: 123  KPDSVRSQLETSLKRLQCPRVDLFYLH-APDHSTPVEETLR--ACHQLHQEGKFVELGLS 179

Query: 674  NYGPKQLLKIHSYLASRGVPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLG 853
            NY   ++ +I +   S G  L +        +  + + EL       G+R  AY+PL  G
Sbjct: 180  NYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVEAELLPCLRHFGLRFYAYNPLAGG 239

Query: 854  MLTGKYD--------------ASNLPNGPRSVLFRQ-ILPGLESLLSCLKSIADRKGKTM 988
            +LTGKY                +N     R+  +++     +  +   L++        M
Sbjct: 240  LLTGKYKYEDKDGKQPVGRFFGNNWAETYRNRFWKEHHFEAIALVEKALQTTYGTNAPRM 299

Query: 989  SQVAINWCI-------CKGAIPIPGVKTVRHVEDNLGAL-GWRLSPGEISELEAA----A 1132
            +  A+ W          +G   I G+ ++  +E NL A     L P  +   + A    A
Sbjct: 300  TSAALRWMYHHSQLQGTRGDAVILGMSSLEQLEQNLAATEEGPLEPAVVEAFDQAWNMVA 359

Query: 1133 MECP 1144
             ECP
Sbjct: 360  HECP 363
to top
>Q4R802:AKCL2_MACFA Aldo-keto reductase family 1 member C-like protein 2 - Macaca|
            fascicularis (Crab eating macaque) (Cynomolgus monkey)
          Length = 320

 Score = 55.1 bits (131), Expect = 6e-07
 Identities = 68/312 (21%), Positives = 125/312 (40%), Gaps = 37/312 (11%)
 Frame = +2

Query: 296  ELQECFNLALKNGINLFDTADSYGTGKLNGQSERLLGKFIRECQGPIKSPDDVVIATKFA 475
            ++ E   +A+  G   F+ A  Y   K  G   R   K     +G ++  +D+ IA+K  
Sbjct: 18   KVTEAVKVAIDAGYRHFNCAYFYHNEKEVGAGIRYKIK-----EGAVRR-EDLFIASKL- 70

Query: 476  AYPWRLTSGQFV--NACRSSLERLQIDRLGIGQLHWSTA--------------------- 586
               W     + +   ACR SL+ L+++ L +  +HW                        
Sbjct: 71   ---WCTCHKKSLVKTACRRSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSFCLSH 127

Query: 587  ---NYAPLQERAL-----------WDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSYLASR 724
               +  PL E  +           W+ + ++   GLV+ +GVSN+  +QL ++ +    R
Sbjct: 128  PGVHDLPLDESDMVIPGDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLR 187

Query: 725  GVPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGMLTGKYDASNLPNGPRS 904
              P+++       L+    Q  L + C S GV + AY PLG     G  +  +L + P  
Sbjct: 188  FKPVTNQIECHPYLT----QKNLISFCQSRGVSVTAYRPLG-----GSCEGVDLIDDP-- 236

Query: 905  VLFRQILPGLESLLSCLKSIADRKGKTMSQVAINWCICKGAIPIPGVKTVRHVEDNLGAL 1084
                            ++ IA    K+ +Q+ I +   +  I IPG  T  H+++N+   
Sbjct: 237  ---------------VIQRIAKEHSKSPAQILIRFQTQRNVIVIPGSITPSHIKENIQVF 281

Query: 1085 GWRLSPGEISEL 1120
             + L+  ++  +
Sbjct: 282  DFELTQHDMDNI 293
to top
>P17264:CRO_RANCA Rho crystallin - Rana catesbeiana (Bull frog)|
          Length = 324

 Score = 54.7 bits (130), Expect = 8e-07
 Identities = 49/172 (28%), Positives = 81/172 (47%)
 Frame = +2

Query: 611  ALWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSYLASRGVPLSSAQVQFSLLSMGEEQME 790
            A W+ L    D GLVR++GVSN+  +QL +I +    +  P+ + QV+  +      Q +
Sbjct: 147  ATWEALEARKDAGLVRSLGVSNFNRRQLERILNKPGLKYKPVCN-QVECHVYL---NQNK 202

Query: 791  LKTVCDSLGVRLIAYSPLGLGMLTGKYDASNLPNGPRSVLFRQILPGLESLLSCLKSIAD 970
            L + C S  + L+ YS LG        D S LP     VL    +         L  IA 
Sbjct: 203  LHSYCKSKDIVLVTYSVLGSHRDRNWVDLS-LP-----VLLDDPI---------LNKIAA 247

Query: 971  RKGKTMSQVAINWCICKGAIPIPGVKTVRHVEDNLGALGWRLSPGEISELEA 1126
            +  +T ++VA+ + + KG + +    T   ++ NLG   + L P ++  LE+
Sbjct: 248  KYNRTSAEVAMRFILQKGIVVLAKSFTPARIKQNLGVFEFELKPEDMKTLES 299
to top
>P82809:AK1CD_MESAU Aldo-keto reductase family 1 member C13 - Mesocricetus auratus|
            (Golden hamster)
          Length = 322

 Score = 54.7 bits (130), Expect = 8e-07
 Identities = 77/328 (23%), Positives = 138/328 (42%), Gaps = 27/328 (8%)
 Frame = +2

Query: 221  VSPMGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQSERL 400
            +  +GFGT+           E   S+  E  NLA+  G    DTA +Y       Q E  
Sbjct: 16   IPALGFGTYK--------PIEVPKSKAMEAANLAIGVGYRHIDTAYAY-------QIEEE 60

Query: 401  LGKFIRE-CQGPIKSPDDVVIATKFAAYPWRLTSGQFVNACRSSLER----LQIDRLGIG 565
            +G+ I+   +  I   +D+ I TK     ++          R SLE+    LQ++ + + 
Sbjct: 61   IGQAIQSNIKAGIVKREDMFITTKLWCTCFQ------PELVRPSLEKXXXKLQLEHVDLF 114

Query: 566  QLHWSTA-----NYAPLQER-----------ALWDGLVEMYDKGLVRAVGVSNYGPKQLL 697
             +H+        N  PL E+           A W+ L +  D GLV+++GVSN+  +QL 
Sbjct: 115  IMHYPVPMKAGDNDFPLDEQGKLLLDTVDFCATWEALEKXXDAGLVKSIGVSNFNMRQLE 174

Query: 698  KIHSYLASRGVPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGMLTGKY-- 871
            +I +    +  P+ + QV+  + +    Q +L   C S  + L+A+  LG    T +Y  
Sbjct: 175  RILNKPGLKYKPVCN-QVECHVYN---NQSKLLDYCKSKDIVLVAFGALG----TQRYKE 226

Query: 872  ----DASNLPNGPRSVLFRQILPGLESLLSCLKSIADRKGKTMSQVAINWCICKGAIPIP 1039
                D+  L N P                  L   A    ++ + +A+ + + +G +P+ 
Sbjct: 227  WVDQDSPVLLNDP-----------------VLCGGAKXXXRSPALIALRYLVQRGVVPLA 269

Query: 1040 GVKTVRHVEDNLGALGWRLSPGEISELE 1123
                   +++NL    ++LSP ++  L+
Sbjct: 270  QSFYESEMKENLQVFEFQLSPEDMKILD 297
to top
>O94735:XYL1_PICGU NADPH-dependent D-xylose reductase - Pichia guilliermondii (Yeast)|
            (Candida guilliermondii)
          Length = 317

 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 68/297 (22%), Positives = 117/297 (39%), Gaps = 24/297 (8%)
 Frame = +2

Query: 320  ALKNGINLFDTADSYGTGKLNGQSERLLGKFIRECQGPIKSPDDVVIATKFAAYPWRLTS 499
            A+K G  LFD A+ YG  K  G+         R     + + D++ + +K     W    
Sbjct: 33   AIKVGYRLFDGAEDYGNEKEVGEGIN------RALDEGLVARDELFVVSKL----WNSFH 82

Query: 500  G--QFVNACRSSLERLQIDRLGIGQLHWSTA-NYAPLQERA------------------- 613
                   A   +L  L++D L +  +H+  A  + P +E+                    
Sbjct: 83   DPKNVEKALDRTLSDLKVDYLDLFLIHFPIAFKFVPFEEKYPPGFYCGDGDKFIYEGVPI 142

Query: 614  --LWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSYLASRGVPLSSAQVQFSLLSMGEEQM 787
               W  L +M +KG +R++G+SN+ P  L++       RG  +  A +Q       ++  
Sbjct: 143  IDTWRALEKMVEKGKIRSIGISNF-PGALIQD----LLRGAKIKPAVLQIEHHPYLQQPR 197

Query: 788  ELKTVCDSLGVRLIAYSPLGLGMLTGKYDASNLPNGPRSVLFRQILPGLESLLSCLKSIA 967
             ++ V  S G+ + AYS  G              N PR    + + P  E     +KS+A
Sbjct: 198  LIEYV-QSQGIAITAYSSFGPQSFVEL-------NHPR---VKDVKPLFEH--DVIKSVA 244

Query: 968  DRKGKTMSQVAINWCICKGAIPIPGVKTVRHVEDNLGALGWRLSPGEISELEAAAME 1138
            ++  KT +QV + W   +G   IP       +  NL    + LS  +  E+    +E
Sbjct: 245  EKANKTPAQVLLRWATQRGLAVIPKSNNPDRLLSNLKVNDFDLSQEDFKEISKLDIE 301
to top
>P80508:PE2R_RABIT Prostaglandin-E(2) 9-reductase - Oryctolagus cuniculus (Rabbit)|
          Length = 323

 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 70/318 (22%), Positives = 132/318 (41%), Gaps = 19/318 (5%)
 Frame = +2

Query: 230  MGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQSERLLGK 409
            +GFGT+A         EE   S+  E   +A+  G    D+A  Y       ++E+ +G 
Sbjct: 19   LGFGTYA--------PEEVPKSKAMEATKIAIDAGFRHIDSAYFY-------KNEKEVGL 63

Query: 410  FIRE--CQGPIKSPDDVVIATKFAAYPWRLTSGQFVN-ACRSSLERLQIDRLGIGQLHWS 580
             IR     G +K  D    +  +  +       + V  +   SL+ LQ+D + +  +H+ 
Sbjct: 64   AIRSKIADGTVKREDIFYTSKLWCTFH----RPELVRPSLEDSLKNLQLDYVDLYIIHFP 119

Query: 581  TA-----NYAPLQER-----------ALWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSY 712
            TA        P  E            A W+ + +  D GL +++GVSN+  +QL  I + 
Sbjct: 120  TALKPGVEIIPTDEHGKAIFDTVDICATWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNK 179

Query: 713  LASRGVPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGMLTGKYDASNLPN 892
               +  P+ +       L+ G    +L   C S G+ L+AYS LG        D S    
Sbjct: 180  PGLKYKPVCNQVECHPYLNQG----KLLEFCKSKGIVLVAYSALGSHREPEWVDQS---- 231

Query: 893  GPRSVLFRQILPGLESLLSCLKSIADRKGKTMSQVAINWCICKGAIPIPGVKTVRHVEDN 1072
                VL    L G         ++A +  +T + +A+ + + +G + +    T + +++N
Sbjct: 232  --APVLLEDPLIG---------ALAKKHQQTPALIALRYQLQRGIVVLAKSFTEKRIKEN 280

Query: 1073 LGALGWRLSPGEISELEA 1126
            +    ++L   ++  +++
Sbjct: 281  IQVFEFQLPSEDMKVIDS 298
to top
>P02532:CRO_RANTE Rho crystallin - Rana temporaria (European common frog)|
          Length = 324

 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 47/172 (27%), Positives = 81/172 (47%)
 Frame = +2

Query: 611  ALWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSYLASRGVPLSSAQVQFSLLSMGEEQME 790
            A W+ L    D GLVR++GVSN+  +QL +I +    +  P+ + QV+  +      Q +
Sbjct: 147  ATWEALEARKDAGLVRSLGVSNFNRRQLERILNKPGLKYKPVCN-QVECHVYL---NQNK 202

Query: 791  LKTVCDSLGVRLIAYSPLGLGMLTGKYDASNLPNGPRSVLFRQILPGLESLLSCLKSIAD 970
            L + C S  + L+ YS LG        D S LP     VL    +         L  +A 
Sbjct: 203  LHSYCKSKDIVLVTYSVLGSHRDRNWVDLS-LP-----VLLDDPI---------LNKVAA 247

Query: 971  RKGKTMSQVAINWCICKGAIPIPGVKTVRHVEDNLGALGWRLSPGEISELEA 1126
            +  +T +++A+ + + KG + +    T   ++ NLG   + L P ++  LE+
Sbjct: 248  KYNRTSAEIAMRFILQKGIVVLAKSFTPARIKQNLGVFEFELKPEDMKSLES 299
to top
>O70473:AK1A1_CRIGR Alcohol dehydrogenase [NADP+] - Cricetulus griseus (Chinese|
           hamster)
          Length = 228

 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 56/226 (24%), Positives = 90/226 (39%), Gaps = 20/226 (8%)
 Frame = +2

Query: 230 MGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQSERLLGK 409
           +G GTW           +S   +++     AL  G    D A  YG       +E  +G+
Sbjct: 2   IGLGTW-----------KSNPGQVKAAIKYALSVGYRHIDCAAVYG-------NEIEIGE 43

Query: 410 FIRECQGPIKSPDDVVIATKFAAYPWRLTSGQFVNACRSSLERLQIDRLGIGQLHW---- 577
            ++E  GP K+     +      +  +        A R +L  LQ++ L +  +HW    
Sbjct: 44  ALKENVGPGKAVPREELFVTSKLWNTKHHPEDVEAALRKTLADLQLEYLDLYLMHWPYAF 103

Query: 578 ------------STANYAPLQERALWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSYLAS 721
                        T  Y     +  W  L  +  KGLV+A+G+SN+  +Q+  I      
Sbjct: 104 ERGDNPFPKNDDGTIRYDSTHYKETWKALEALVAKGLVKALGLSNFNSRQIDDI------ 157

Query: 722 RGVPLSSAQVQFSLLSMG----EEQMELKTVCDSLGVRLIAYSPLG 847
               LS A V+ ++L +       Q EL   C + G+ + AYSPLG
Sbjct: 158 ----LSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLG 199
to top
>Q8NHP1:ARK74_HUMAN Aflatoxin B1 aldehyde reductase member 4 - Homo sapiens (Human)|
          Length = 331

 Score = 53.5 bits (127), Expect = 2e-06
 Identities = 77/309 (24%), Positives = 124/309 (40%), Gaps = 31/309 (10%)
 Frame = +2

Query: 323  LKNGINLFDTADSYGTGKLNGQSERLLGKFIRECQGPIKSPDDVVIATKFAAYPW---RL 493
            L+ G    DTA  Y     +GQSE +LG           S   V IATK  A PW    L
Sbjct: 36   LERGHTEIDTAFLYS----DGQSETILGGLGLRMGS---SDCRVKIATK--ANPWIGNSL 86

Query: 494  TSGQFVNACRSSLERLQIDRLGIGQLHWSTANYAPLQERALWDGLVEMYDKGLVRAVGVS 673
                  +   +SL+RLQ   + +  LH +  + AP++E        +++ +G    +G+S
Sbjct: 87   KPDSVRSQLETSLKRLQCPCVDLFYLH-APDHSAPVEETLR--ACHQLHQEGKFVELGLS 143

Query: 674  NYGPKQLLKIHSYLASRGVPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLG 853
            NY   ++ +I +   S G  L +        +  + + EL       G+R  AY+PL  G
Sbjct: 144  NYAAWEVAEICTLCKSNGWILPTVYQGMYSATTRQVETELFPYLRHFGLRFYAYNPLAGG 203

Query: 854  MLTGKYDASNLPNGPRSV----------LFR------QILPGLESLLSCLKSIADRKGKT 985
            +LTGKY   +  +G + V          ++R          G+  +   L++       +
Sbjct: 204  LLTGKYKYED-KDGKQPVGRFFGTQWAEIYRNHFWKEHHFEGIALVEKALQATYGASAPS 262

Query: 986  MSQVAINWCI-------CKGAIPIPGVKTVRHVEDNLGAL-GWRLSPGEISELEAA---- 1129
            M+  A+ W           G   I G+ ++  +E NL A     L P  +     A    
Sbjct: 263  MTSAALRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLAAAEEGPLEPAVVDAFNQAWHLF 322

Query: 1130 AMECPKKMV 1156
            A ECP   +
Sbjct: 323  AHECPNYFI 331
to top
>P27800:ALDX_SPOSA Aldehyde reductase 1 - Sporobolomyces salmonicolor|
          Length = 323

 Score = 53.5 bits (127), Expect = 2e-06
 Identities = 74/306 (24%), Positives = 119/306 (38%), Gaps = 21/306 (6%)
 Frame = +2

Query: 218  SVSPMGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQSER 397
            S+  +G+GTW           ++   E+ +   +A++ G    D A  Y     + Q E 
Sbjct: 12   SLELVGYGTW-----------QAAPGEVGQGVKVAIETGYRHLDLAKVY-----SNQPE- 54

Query: 398  LLGKFIRECQGPIKSPDDVVIATKFAAYPWRLTSGQFVNACRSSLERLQIDRLGIGQLHW 577
             +G  I+E        +D+ I +K      R    Q   A   +L+ L ++ L +  +HW
Sbjct: 55   -VGAAIKEAG---VKREDLFITSKLWNNSHR--PEQVEPALDDTLKELGLEYLDLYLIHW 108

Query: 578  STA---------NYAPLQERA------------LWDGLVEMYDKGLVRAVGVSNYGPKQL 694
              A         N  P                  W  +V++ D G V+A+GVSN+  K  
Sbjct: 109  PVAFPPEGDITQNLFPKANDKEVKLDLEVSLVDTWKAMVKLLDTGKVKAIGVSNFDAKM- 167

Query: 695  LKIHSYLASRGVPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGMLTGKYD 874
              + + + + GV  S  Q++   L +   Q EL     +  + + AYSPLG         
Sbjct: 168  --VDAIIEATGVTPSVNQIERHPLLL---QPELIAHHKAKNIHITAYSPLG--------- 213

Query: 875  ASNLPNGPRSVLFRQILPGLESLLSCLKSIADRKGKTMSQVAINWCICKGAIPIPGVKTV 1054
             +N    P  V   +I           K IA++ G T +QV I W I  G   IP   T 
Sbjct: 214  -NNTVGAPLLVQHPEI-----------KRIAEKNGCTPAQVLIAWAIVGGHSVIPKSVTP 261

Query: 1055 RHVEDN 1072
              + +N
Sbjct: 262  SRIGEN 267
to top
>P51857:AK1D1_HUMAN 3-oxo-5-beta-steroid 4-dehydrogenase - Homo sapiens (Human)|
          Length = 326

 Score = 53.5 bits (127), Expect = 2e-06
 Identities = 45/172 (26%), Positives = 79/172 (45%)
 Frame = +2

Query: 611  ALWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSYLASRGVPLSSAQVQFSLLSMGEEQME 790
            A W+ +    D GLV+++GVSN+  +QL  I +    +  P+S+ QV+         Q +
Sbjct: 149  ATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSN-QVECHPYF---TQPK 204

Query: 791  LKTVCDSLGVRLIAYSPLGLGMLTGKYDASNLPNGPRSVLFRQILPGLESLLSCLKSIAD 970
            L   C    + + AYSPLG        + S+ P      L +  L         L S+  
Sbjct: 205  LLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPP------LLKDAL---------LNSLGK 249

Query: 971  RKGKTMSQVAINWCICKGAIPIPGVKTVRHVEDNLGALGWRLSPGEISELEA 1126
            R  KT +Q+ + + I +G + IP    +  +++N     + L+  E+ ++EA
Sbjct: 250  RYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKENFQIFDFSLTEEEMKDIEA 301
to top
>P97382:KCAB3_MOUSE Voltage-gated potassium channel subunit beta-3 - Mus musculus (Mouse)|
          Length = 249

 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 49/217 (22%), Positives = 107/217 (49%), Gaps = 15/217 (6%)
 Frame = +2

Query: 521  RSSLERLQIDRLGIGQLHWSTANYAPLQERALWDGLVEMYDKGLVRAVGVSNYGPKQLLK 700
            + SL+RLQ++ + I   + S  N +P++E  +   +  + ++GL    G S +   ++++
Sbjct: 27   QGSLDRLQLEYVDIVFANRSDPN-SPMEE--IVRAMTYVINQGLALYWGTSRWSAAEIME 83

Query: 701  IHSYLASRG-VPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGMLTGKYDA 877
             +S       +P    Q +       + +M+L  +   +GV  + +SPL  G++T KYD 
Sbjct: 84   AYSMARQFNLIPPVCEQAENHFFQREKVEMQLPELYHKIGVGSVTWSPLACGLITSKYD- 142

Query: 878  SNLPNGPRSVL--FRQILPGLES--------LLSCLKSIADRKGKTMSQVAINWCICKGA 1027
              +P+  ++ +  ++ +   ++S         +  L   A + G T+ Q+AI WC+    
Sbjct: 143  GRVPDTCKATVKGYQWLKEKVQSEEGKKQQARVMDLLPTARQLGCTVGQLAIAWCLRSEG 202

Query: 1028 IP--IPGVKTVRHVEDNLGALG--WRLSPGEISELEA 1126
            +   + GV +   + ++LG+L    +L+P  + E++A
Sbjct: 203  VSSVLLGVSSAEQLMEHLGSLQVLSQLTPQTVVEIDA 239
to top
>P38918:ARK73_RAT Aflatoxin B1 aldehyde reductase member 3 - Rattus norvegicus (Rat)|
          Length = 327

 Score = 52.0 bits (123), Expect = 5e-06
 Identities = 74/302 (24%), Positives = 119/302 (39%), Gaps = 28/302 (9%)
 Frame = +2

Query: 323  LKNGINLFDTADSYGTGKLNGQSERLLGKFIRECQGPIKSPDDVVIATKFAA-YPWRLTS 499
            L+ G    DTA  Y     NGQSE +LG       G  +S   V IATK A  +   L  
Sbjct: 32   LQRGHTEIDTAFVYA----NGQSETILGDL---GLGLGRSGCKVKIATKAAPMFGKTLKP 84

Query: 500  GQFVNACRSSLERLQIDRLGIGQLHWSTANYAPLQERALWDGLVEMYDKGLVRAVGVSNY 679
                    +SL+RLQ  R+ +  LH+      P++E        +++ +G    +G+SNY
Sbjct: 85   ADVRFQLETSLKRLQCPRVDLFYLHFPDHG-TPIEETL--QACHQLHQEGKFVELGLSNY 141

Query: 680  GPKQLLKIHSYLASRGVPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGML 859
               ++ +I +     G  + +           + + EL       G+R  A++PL  G+L
Sbjct: 142  VSWEVAEICTLCKKNGWIMPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNPLAGGLL 201

Query: 860  TGKY---------DASNLPNGPRSVLF------RQILPGLESLLSCLKSIADRKGKTMSQ 994
            TG+Y           S     P S L+       +   G+  +   LK+       +M  
Sbjct: 202  TGRYKYQDKDGKNPESRFFGNPFSQLYMDRYWKEEHFNGIALVEKALKTTYGPTAPSMIS 261

Query: 995  VAINWCI-------CKGAIPIPGVKTVRHVEDNLGAL-GWRLSPGEISELEAA----AME 1138
             A+ W          +G   I G+ ++  +E NL  +    L P  +   + A    A E
Sbjct: 262  AAVRWMYHHSQLKGTQGDAVILGMSSLEQLEQNLALVEEGPLEPAVVDAFDQAWNLVAHE 321

Query: 1139 CP 1144
            CP
Sbjct: 322  CP 323
to top
>O43488:ARK72_HUMAN Aflatoxin B1 aldehyde reductase member 2 - Homo sapiens (Human)|
          Length = 359

 Score = 51.6 bits (122), Expect = 7e-06
 Identities = 54/186 (29%), Positives = 83/186 (44%), Gaps = 3/186 (1%)
 Frame = +2

Query: 323 LKNGINLFDTADSYGTGKLNGQSERLLGKFIRECQGPIKSPDDVVIATKFAAYPW---RL 493
           L+ G    DTA  Y     +GQSE +LG       G       V IATK  A PW    L
Sbjct: 64  LERGHTELDTAFMYS----DGQSETILGGLGLGLGG---GDCRVKIATK--ANPWDGKSL 114

Query: 494 TSGQFVNACRSSLERLQIDRLGIGQLHWSTANYAPLQERALWDGLVEMYDKGLVRAVGVS 673
                 +   +SL+RLQ  ++ +  LH +  +  P++E         ++ +G    +G+S
Sbjct: 115 KPDSVRSQLETSLKRLQCPQVDLFYLH-APDHGTPVEETL--HACQRLHQEGKFVELGLS 171

Query: 674 NYGPKQLLKIHSYLASRGVPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLG 853
           NY   ++ +I +   S G  L +        +  + + EL       G+R  AY+PL  G
Sbjct: 172 NYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNPLAGG 231

Query: 854 MLTGKY 871
           +LTGKY
Sbjct: 232 LLTGKY 237
to top
>P14065:GCY_YEAST Protein GCY - Saccharomyces cerevisiae (Baker's yeast)|
          Length = 312

 Score = 51.2 bits (121), Expect = 9e-06
 Identities = 61/234 (26%), Positives = 98/234 (41%), Gaps = 25/234 (10%)
 Frame = +2

Query: 221 VSPMGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQSERL 400
           +  +G GTW           +S +++  +    ALK+G    DTA  Y       ++E  
Sbjct: 20  IPQIGLGTW-----------QSKENDAYKAVLTALKDGYRHIDTAAIY-------RNEDQ 61

Query: 401 LGKFIRECQGPIKSPDDVVIATKFAAYPWRLTSGQFVNACRSSLERLQIDRLGIGQLHWS 580
           +G+ I++   P    +++ + TK     W     +   A   SL+RL +D + +  +HW 
Sbjct: 62  VGQAIKDSGVP---REEIFVTTKL----WCTQHHEPEVALDQSLKRLGLDYVDLYLMHWP 114

Query: 581 TANYAPLQ---------------ERAL----------WDGLVEMYDKGLVRAVGVSNYGP 685
            A   P                  RA+          W+ + E+   G  +AVGVSN+  
Sbjct: 115 -ARLDPAYIKNEDILSVPTKKDGSRAVDITNWNFIKTWELMQELPKTGKTKAVGVSNFSI 173

Query: 686 KQLLKIHSYLASRGVPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLG 847
             L  +   LAS+G  L+ A  Q  +  +   Q EL   C S G+ + AYSPLG
Sbjct: 174 NNLKDL---LASQGNKLTPAANQVEIHPL-LPQDELINFCKSKGIVVEAYSPLG 223
to top
>P31210:AK1D1_RAT 3-oxo-5-beta-steroid 4-dehydrogenase - Rattus norvegicus (Rat)|
          Length = 326

 Score = 51.2 bits (121), Expect = 9e-06
 Identities = 44/172 (25%), Positives = 75/172 (43%)
 Frame = +2

Query: 611  ALWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSYLASRGVPLSSAQVQFSLLSMGEEQME 790
            A W+ L    D GLV+++GVSN+  +QL  I   L   G+       Q        +   
Sbjct: 148  ATWEALEACKDAGLVKSLGVSNFNRRQLEVI---LNKPGLKYKPVTNQVECHPYFTQTKL 204

Query: 791  LKTVCDSLGVRLIAYSPLGLGMLTGKYDASNLPNGPRSVLFRQILPGLESLLSCLKSIAD 970
            L+    S+   ++AYSPLG        + S+ P      L +  L         L S+  
Sbjct: 205  LEVSASSMTSFIVAYSPLGTCRNPLWVNVSSPP------LLKDEL---------LTSLGK 249

Query: 971  RKGKTMSQVAINWCICKGAIPIPGVKTVRHVEDNLGALGWRLSPGEISELEA 1126
            +  KT +Q+ + + I +G + IP   T   +++N     + L+  E+ ++EA
Sbjct: 250  KYNKTQAQIVLRFDIQRGLVVIPKSTTPERIKENFQIFDFSLTKEEMKDIEA 301
to top
>O13283:XYL1_CANTR NAD(P)H-dependent D-xylose reductase I,II - Candida tropicalis|
            (Yeast)
          Length = 324

 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 71/335 (21%), Positives = 130/335 (38%), Gaps = 24/335 (7%)
 Frame = +2

Query: 188  PWEKVNVGPLSVSPMGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYG 367
            P  K+N G   +  +GFG W   N           +   + +N A+K G  LFD A+ YG
Sbjct: 8    PTIKLNSG-YEMPLVGFGCWKVTNA----------TAADQIYN-AIKTGYRLFDGAEDYG 55

Query: 368  TGKLNGQSERLLGKFIRECQGPIKSPDDVVIATKFAAYPWRLTSG--QFVNACRSSLERL 541
              K  G+    + + I+E  G +K  +++ I +K     W           A   +L  L
Sbjct: 56   NEKEVGEG---INRAIKE--GLVKR-EELFITSKL----WNNFHDPKNVETALNKTLSDL 105

Query: 542  QIDRLGIGQLHWSTA-NYAPLQERA---------------------LWDGLVEMYDKGLV 655
             +D + +  +H+  A  + P++E+                       W  L ++ + G +
Sbjct: 106  NLDYVDLFLIHFPIAFKFVPIEEKYPPGFYCGDGDNFHYEDVPLLDTWKALEKLVEAGKI 165

Query: 656  RAVGVSNYGPKQLLKIHSYLASRGVPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAY 835
            +++G+SN+    +     Y   RG  +  A +Q        +Q +L       G+ +  Y
Sbjct: 166  KSIGISNFTGALI-----YDLIRGATIKPAVLQIEHHPY-LQQPKLIEYVQKAGIAITGY 219

Query: 836  SPLGLGMLTGKYDASNLPNGPRSVLFRQILPGLESLLSCLKSIADRKGKTMSQVAINWCI 1015
            S  G      + ++    N P   LF             +K IAD+ GK+ +QV + W  
Sbjct: 220  SSFGPQSFL-ELESKRALNTP--TLFEH---------ETIKLIADKHGKSPAQVLLRWAT 267

Query: 1016 CKGAIPIPGVKTVRHVEDNLGALGWRLSPGEISEL 1120
             +    IP       +  NL  + + L+  ++  +
Sbjct: 268  QRNIAVIPKSNNPERLAQNLSVVDFDLTKDDLDNI 302
to top
>P17516:AK1C4_HUMAN Aldo-keto reductase family 1 member C4 - Homo sapiens (Human)|
          Length = 323

 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 73/317 (23%), Positives = 134/317 (42%), Gaps = 19/317 (5%)
 Frame = +2

Query: 230  MGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQSERLLGK 409
            +GFGT+A          E   +   E   LA++ G    D+A  Y        +E  +G 
Sbjct: 19   LGFGTYA--------PPEVPRNRAVEVTKLAIEAGFRHIDSAYLYN-------NEEQVGL 63

Query: 410  FIRE--CQGPIKSPDDVVIATKFAAYPWRLTSGQFVN-ACRSSLERLQIDRLGIGQLHWS 580
             IR     G +K  D    +  +  +       Q V  A  SSL++LQ+D + +  LH+ 
Sbjct: 64   AIRSKIADGSVKREDIFYTSKLWCTF----FQPQMVQPALESSLKKLQLDYVDLYLLHFP 119

Query: 581  TA---NYAPLQE-------------RALWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSY 712
             A      PL +              A W+ + +  D GL +++GVSN+  +QL  I + 
Sbjct: 120  MALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNK 179

Query: 713  LASRGVPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGMLTGKYDASNLPN 892
               +  P+ +       L+    Q +L   C S  + L+A+S LG    T ++     PN
Sbjct: 180  PGLKYKPVCNQVECHPYLN----QSKLLDFCKSKDIVLVAHSALG----TQRHKLWVDPN 231

Query: 893  GPRSVLFRQILPGLESLLSCLKSIADRKGKTMSQVAINWCICKGAIPIPGVKTVRHVEDN 1072
             P  VL       LE  + C  ++A +  +T + +A+ + + +G + +      + + +N
Sbjct: 232  SP--VL-------LEDPVLC--ALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIREN 280

Query: 1073 LGALGWRLSPGEISELE 1123
            +    ++L+  ++  L+
Sbjct: 281  IQVFEFQLTSEDMKVLD 297
to top
>Q8VCX1:AK1D1_MOUSE 3-oxo-5-beta-steroid 4-dehydrogenase - Mus musculus (Mouse)|
          Length = 325

 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 43/172 (25%), Positives = 79/172 (45%)
 Frame = +2

Query: 611  ALWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSYLASRGVPLSSAQVQFSLLSMGEEQME 790
            A W+ L    D GLV+++GVSN+  +QL  I +    +  P+++ QV+         Q +
Sbjct: 148  ATWEALEACKDAGLVKSLGVSNFNRRQLELILNKPGLKYKPVTN-QVECHPYF---TQTK 203

Query: 791  LKTVCDSLGVRLIAYSPLGLGMLTGKYDASNLPNGPRSVLFRQILPGLESLLSCLKSIAD 970
            L   C    + ++A+SPLG        + S+ P      L    L         L S+  
Sbjct: 204  LLKFCQQHDIVIVAHSPLGTCRNPSWVNVSSPP------LLNDEL---------LTSLGK 248

Query: 971  RKGKTMSQVAINWCICKGAIPIPGVKTVRHVEDNLGALGWRLSPGEISELEA 1126
            +  KT +Q+ + + I +G + IP   T   +++N     + L+  E+ +++A
Sbjct: 249  KYNKTQAQIVLRFNIQRGIVVIPKSFTPERIKENFQIFDFSLTEEEMKDIDA 300
to top
>Q9TV64:AK1D1_RABIT 3-oxo-5-beta-steroid 4-dehydrogenase - Oryctolagus cuniculus (Rabbit)|
          Length = 326

 Score = 48.5 bits (114), Expect = 6e-05
 Identities = 43/172 (25%), Positives = 80/172 (46%)
 Frame = +2

Query: 611  ALWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSYLASRGVPLSSAQVQFSLLSMGEEQME 790
            A W+ L    D GLV+++GVSN+  +QL  + +    +  P+ + QV+         Q +
Sbjct: 149  ATWEALEACKDAGLVKSLGVSNFNRQQLELLLNKPGLKHKPVCN-QVECHPYF---TQPK 204

Query: 791  LKTVCDSLGVRLIAYSPLGLGMLTGKYDASNLPNGPRSVLFRQILPGLESLLSCLKSIAD 970
            L   C    + ++AYSPLG       +  ++LP            P L+  L  L S+  
Sbjct: 205  LLKFCQQHDIIIVAYSPLGT-CRNPMWVNTSLP------------PLLKDTL--LNSLGK 249

Query: 971  RKGKTMSQVAINWCICKGAIPIPGVKTVRHVEDNLGALGWRLSPGEISELEA 1126
            +  KT +Q+ + + + +G + IP       +++N     + L+  E+ ++EA
Sbjct: 250  KYKKTAAQIVLRFNVQRGVVVIPKSFNPERIKENFQIFDFSLTEEEMKDIEA 301
to top
>Q04828:AK1C1_HUMAN Aldo-keto reductase family 1 member C1 - Homo sapiens (Human)|
          Length = 323

 Score = 48.5 bits (114), Expect = 6e-05
 Identities = 74/317 (23%), Positives = 132/317 (41%), Gaps = 19/317 (5%)
 Frame = +2

Query: 230  MGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQSERLLGK 409
            +GFGT+A          E   S+  E   LA++ G    D+A  Y        +E  +G 
Sbjct: 19   LGFGTYAPA--------EVPKSKALEATKLAIEAGFRHIDSAHLYN-------NEEQVGL 63

Query: 410  FIRE--CQGPIKSPDDVVIATKFAAYPWRLTSGQFVN-ACRSSLERLQIDRLGIGQLHWS 580
             IR     G +K  +D+   +K      R    + V  A   SL+ LQ+D + +  +H+ 
Sbjct: 64   AIRSKIADGSVKR-EDIFYTSKLWCNSHR---PELVRPALERSLKNLQLDYVDLYLIHFP 119

Query: 581  TA-----NYAPLQER-----------ALWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSY 712
             +        P  E            A W+ + +  D GL +++GVSN+  +QL  I + 
Sbjct: 120  VSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNK 179

Query: 713  LASRGVPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGMLTGKYDASNLPN 892
               +  P+ + QV+         Q +L   C S  + L+AYS LG        D    PN
Sbjct: 180  PGLKYKPVCN-QVECHPYF---NQRKLLDFCKSKDIVLVAYSALGSHREEPWVD----PN 231

Query: 893  GPRSVLFRQILPGLESLLSCLKSIADRKGKTMSQVAINWCICKGAIPIPGVKTVRHVEDN 1072
             P  VL       LE  + C  ++A +  +T + +A+ + + +G + +      + +  N
Sbjct: 232  SP--VL-------LEDPVLC--ALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQN 280

Query: 1073 LGALGWRLSPGEISELE 1123
            +    ++L+  E+  ++
Sbjct: 281  VQVFEFQLTSEEMKAID 297
to top
>P30863:DKGB_ECOLI 2,5-diketo-D-gluconic acid reductase B - Escherichia coli|
          Length = 267

 Score = 48.1 bits (113), Expect = 8e-05
 Identities = 58/281 (20%), Positives = 111/281 (39%), Gaps = 2/281 (0%)
 Frame = +2

Query: 320  ALKNGINLFDTADSYGTGKLNGQSERLLGKFIRECQGPIKSPDDVVIATKFAAYPW--RL 493
            AL+ G    DTA  Y        +E  +G+ I E   P     ++ I TK     W   L
Sbjct: 25   ALELGYRAIDTAQIY-------DNEAAVGQAIAESGVP---RHELYITTKI----WIENL 70

Query: 494  TSGQFVNACRSSLERLQIDRLGIGQLHWSTANYAPLQERALWDGLVEMYDKGLVRAVGVS 673
            +  + + + + SL++L+ D + +  +HW + N     E  +   L+E   +GL R +G+S
Sbjct: 71   SKDKLIPSLKESLQKLRTDYVDLTLIHWPSPNDEVSVEEFM-QALLEAKKQGLTREIGIS 129

Query: 674  NYGPKQLLKIHSYLASRGVPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLG 853
            N+    + K  + + +  +  +  +     LS   +  ++       G+ + +Y  L  G
Sbjct: 130  NFTIPLMEKAIAAVGAENIATNQIE-----LSPYLQNRKVVAWAKQHGIHITSYMTLAYG 184

Query: 854  MLTGKYDASNLPNGPRSVLFRQILPGLESLLSCLKSIADRKGKTMSQVAINWCICKGAIP 1033
                                             +  IA +   T +QV + W + +G   
Sbjct: 185  KALKD--------------------------EVIARIAAKHNATPAQVILAWAMGEGYSV 218

Query: 1034 IPGVKTVRHVEDNLGALGWRLSPGEISELEAAAMECPKKMV 1156
            IP     +++E NL A   +L   +   +  AA++C  ++V
Sbjct: 219  IPSSTKRKNLESNLKAQNLQLDAEDKKAI--AALDCNDRLV 257
to top
>Q95JH5:AK1C4_MACFA Aldo-keto reductase family 1 member C4 - Macaca fascicularis (Crab|
            eating macaque) (Cynomolgus monkey)
          Length = 323

 Score = 48.1 bits (113), Expect = 8e-05
 Identities = 69/316 (21%), Positives = 135/316 (42%), Gaps = 18/316 (5%)
 Frame = +2

Query: 230  MGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQSERLLGK 409
            +GFGT+A          E   + + E   LA++ G    D+A  Y        +E  +G 
Sbjct: 19   LGFGTYA--------PPEVPRNRVVEVTKLAIEAGFRHIDSAYLYN-------NEEQVGL 63

Query: 410  FIRE--CQGPIKSPDDVVIATKFAAYPWRLTSGQFVNACRSSLERLQIDRLGIGQLHWST 583
             IR     G +K  +D+   +K     +R    Q   A  SSL++LQ+D + +  +H+  
Sbjct: 64   AIRSKIADGSVKR-EDIFYTSKLWCTFFRPQLVQ--PALESSLKKLQLDYVDLYLIHFPM 120

Query: 584  A---NYAPLQER-------------ALWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSYL 715
            A      PL +              A+W+ + +  D GL +++GVSN+  +QL  I +  
Sbjct: 121  ALKPGETPLPKDENGKVMFDTVDLCAIWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNNP 180

Query: 716  ASRGVPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGMLTGKYDASNLPNG 895
              +  P+ +       L+    Q +L   C S  + L+A+S LG    T ++      N 
Sbjct: 181  GLKYKPVCNQVECHPYLN----QSKLLDFCKSKDIVLVAHSALG----TQRHKLWVDQNS 232

Query: 896  PRSVLFRQILPGLESLLSCLKSIADRKGKTMSQVAINWCICKGAIPIPGVKTVRHVEDNL 1075
            P           LE  + C  ++A +  ++ + +A+ + + +G + +      + + +N+
Sbjct: 233  PAL---------LEDPVLC--ALAKKHKRSPALIALRYQLQRGVVVLAKSYNEQRIRENV 281

Query: 1076 GALGWRLSPGEISELE 1123
                ++L+  ++  L+
Sbjct: 282  QVFEFQLTSEDMKVLD 297
to top
>Q95JH6:AK1C1_MACFU Aldo-keto reductase family 1 member C1 homolog - Macaca fuscata|
            fuscata (Japanese macaque)
          Length = 323

 Score = 48.1 bits (113), Expect = 8e-05
 Identities = 71/317 (22%), Positives = 132/317 (41%), Gaps = 19/317 (5%)
 Frame = +2

Query: 230  MGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQSERLLGK 409
            +GFGT+A          E   ++  E   LA++ G    D+A  Y        +E  +G 
Sbjct: 19   LGFGTYAPA--------EVPKNKAIEATKLAIEAGFRHIDSAHLYN-------NEEYVGL 63

Query: 410  FIRE--CQGPIKSPDDVVIATKFAAYPWRLTSGQFVN-ACRSSLERLQIDRLGIGQLHWS 580
             IR     G +K  +D+   +K      R    +FV  A   SL+ LQ+D + +  +H+ 
Sbjct: 64   AIRSKIADGTVKR-EDIFYTSKLWCNSHR---PEFVRPALERSLKNLQLDYVDLYLIHFP 119

Query: 581  TA-----NYAPLQER-----------ALWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSY 712
             +        P  E            A W+ + +  D GL +++GVSN+  +QL  I + 
Sbjct: 120  VSLKPGEELIPKDENGKLLFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNK 179

Query: 713  LASRGVPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGMLTGKYDASNLPN 892
               +  P+ +       L+    Q +L   C S  + L+AYS LG        D     N
Sbjct: 180  PGLKYKPVCNQVECHPYLN----QRKLLDFCKSKDIVLVAYSALGSHREKPWVD----QN 231

Query: 893  GPRSVLFRQILPGLESLLSCLKSIADRKGKTMSQVAINWCICKGAIPIPGVKTVRHVEDN 1072
             P  VL       LE  + C  ++A +  +T + +A+ + + +G + +      + + +N
Sbjct: 232  SP--VL-------LEDPVLC--ALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIREN 280

Query: 1073 LGALGWRLSPGEISELE 1123
            +    ++L+  ++  ++
Sbjct: 281  MKVFEFQLTSEDMKAID 297
to top
>Q9P430:XYL1_CANSH NAD(P)H-dependent D-xylose reductase - Candida shehatae (Yeast)|
          Length = 323

 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 72/339 (21%), Positives = 130/339 (38%), Gaps = 28/339 (8%)
 Frame = +2

Query: 188  PWEKVNVGPLSVSPMGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYG 367
            P  K+N G L +  +GFG W          +    +   + +N A+K G  LFD A+ YG
Sbjct: 7    PAFKLNNG-LEMPSIGFGCW----------KLDKSTAADQVYN-AIKAGYRLFDGAEDYG 54

Query: 368  TGKLNGQSERLLGKFIRECQGPIKSPDDVVIATKFAAYPWRLTSG--QFVNACRSSLERL 541
              +  G+  +      R     I + +++ + +K     W           A   +L+ L
Sbjct: 55   NEQEVGEGVK------RAIDEGIVTREEIFLTSKL----WNNYHDPKNVETALNKTLKDL 104

Query: 542  QIDRLGIGQLHWSTA-NYAPLQER---------------------ALWDGLVEMYDKGLV 655
            ++D + +  +H+  A  + P++E+                       W  L ++   G +
Sbjct: 105  KVDYVDLFLIHFPIAFKFVPIEEKYPPGFYCGDGDNFVYEDVPILETWKALEKLVKAGKI 164

Query: 656  RAVGVSNYGPKQLLKIHSYLASRGVPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAY 835
            R++GVSN+    LL +      RG  +  A +Q        +Q +L      +G+ + AY
Sbjct: 165  RSIGVSNFPGALLLDLF-----RGATIKPAVLQVEHHPY-LQQPKLIEYAQKVGITVTAY 218

Query: 836  SPLG----LGMLTGKYDASNLPNGPRSVLFRQILPGLESLLSCLKSIADRKGKTMSQVAI 1003
            S  G    + M  G+  A N P      LF             +K+IA +  K  ++V +
Sbjct: 219  SSFGPQSFVEMNQGR--ALNTP-----TLFEH---------DVIKAIAAKHNKVPAEVLL 262

Query: 1004 NWCICKGAIPIPGVKTVRHVEDNLGALGWRLSPGEISEL 1120
             W   +G   IP       +  N     + L+  +  E+
Sbjct: 263  RWSAQRGIAVIPKSNLPERLVQNRSFNDFELTKEDFEEI 301
to top
>Q5REQ0:AK1C1_PONPY Aldo-keto reductase family 1 member C1 homolog - Pongo pygmaeus|
            (Orangutan)
          Length = 323

 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 73/317 (23%), Positives = 132/317 (41%), Gaps = 19/317 (5%)
 Frame = +2

Query: 230  MGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQSERLLGK 409
            +GFGT+A          E   S+  E   LA++ G    D+A  Y        +E  +G 
Sbjct: 19   LGFGTYA--------PPEVPKSKALEATKLAIEAGFRHIDSAHLYN-------NEEQVGL 63

Query: 410  FIRE--CQGPIKSPDDVVIATKFAAYPWRLTSGQFVN-ACRSSLERLQIDRLGIGQLHWS 580
             IR     G +K  +D+   +K      R    + V  A   SL+ LQ+D + +  +H+ 
Sbjct: 64   AIRSKIADGSVKR-EDIFYTSKLWCNSHR---PELVRPALERSLKNLQLDYVDLYLVHFP 119

Query: 581  TA-----NYAPLQER-----------ALWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSY 712
             +        P  E            A W+ + +  D GL +++GVSN+  +QL  I + 
Sbjct: 120  VSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNK 179

Query: 713  LASRGVPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGMLTGKYDASNLPN 892
               +  P+ + QV+         Q +L   C S  + L+AYS LG        D    PN
Sbjct: 180  PGLKYKPVCN-QVECHPYF---NQRKLLDFCKSKDIVLVAYSALGSHREEKWVD----PN 231

Query: 893  GPRSVLFRQILPGLESLLSCLKSIADRKGKTMSQVAINWCICKGAIPIPGVKTVRHVEDN 1072
             P  VL       LE  + C  ++A +  +T + +A+ + + +G + +      + +  N
Sbjct: 232  SP--VL-------LEDPVLC--ALAKKHKQTPALIALRYQLQRGVVVLAKSYNEQRIRQN 280

Query: 1073 LGALGWRLSPGEISELE 1123
            +    ++L+  ++  ++
Sbjct: 281  MQVFDFQLTSEDMKTID 297
to top
>Q12458:YPR1_YEAST Putative reductase 1 - Saccharomyces cerevisiae (Baker's yeast)|
          Length = 312

 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 71/306 (23%), Positives = 115/306 (37%), Gaps = 28/306 (9%)
 Frame = +2

Query: 197  KVNVGPLSVSPMGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGK 376
            K+N G  S+  +GFGTW            S+D+        ALK G    D A  Y    
Sbjct: 13   KLNTGA-SIPVLGFGTW-----------RSVDNNGYHSVIAALKAGYRHIDAAAIY---- 56

Query: 377  LNGQSERLLGKFIRECQGPIKSPDDVVIATKFAAYPWRLTSGQFVNACRSSLERLQIDRL 556
                +E  +G+ I++   P    +++ I TK     W         A   SL+RL +D +
Sbjct: 57   ---LNEEEVGRAIKDSGVP---REEIFITTKL----WGTEQRDPEAALNKSLKRLGLDYV 106

Query: 557  GIGQLHWSTANYAPLQERALWDGLV----------------------------EMYDKGL 652
             +  +HW      PL+   + DG V                            E+   G 
Sbjct: 107  DLYLMHWPV----PLKTDRVTDGNVLCIPTLEDGTVDIDTKEWNFIKTWELMQELPKTGK 162

Query: 653  VRAVGVSNYGPKQLLKIHSYLASRGVPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIA 832
             +AVGVSN+    + ++     ++ VP ++      LL     Q EL   C   G+ + A
Sbjct: 163  TKAVGVSNFSINNIKELLESPNNKVVPATNQIEIHPLL----PQDELIAFCKEKGIVVEA 218

Query: 833  YSPLGLGMLTGKYDASNLPNGPRSVLFRQILPGLESLLSCLKSIADRKGKTMSQVAINWC 1012
            YSP G         ++N P      L ++           +  +A + G   +Q+ I+W 
Sbjct: 219  YSPFG---------SANAP------LLKE---------QAIIDMAKKHGVEPAQLIISWS 254

Query: 1013 ICKGAI 1030
            I +G +
Sbjct: 255  IQRGYV 260
to top
>Q6Y0Z3:XYL1_CANPA NADH-dependent D-xylose reductase - Candida parapsilosis (Yeast)|
          Length = 324

 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 74/346 (21%), Positives = 141/346 (40%), Gaps = 28/346 (8%)
 Frame = +2

Query: 188  PWEKVNVGPLSVSPMGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYG 367
            P  K+N G   +  +GFG W   N +             +    A+K+G  LFD A+ Y 
Sbjct: 8    PAVKLNSG-YEIPLVGFGCWKLTNDVA-----------SDQIYRAIKSGYRLFDGAEDYA 55

Query: 368  TGKLNGQSERLLGKFIREC--QGPIKSPDDVVIATKFAAYPWRLTSGQFVNACRSSLERL 541
                   +E+ +G+ I+    +G +K  +  + +  + ++           A   +L  L
Sbjct: 56   -------NEQEVGEGIKRAIKEGIVKREELFITSKLWNSFH---DKKNVEVALMKTLSDL 105

Query: 542  QIDRLGIGQLHWSTAN--------YAP-----------LQERAL---WDGLVEMYDKGLV 655
             +D + +  +H+  A         Y P           ++E  L   W  L ++ D+GL 
Sbjct: 106  NLDYVDLFYIHFPIAQKPVPIEKKYPPGFYCGDGDKWSIEEVPLLDTWRALEKLVDQGLA 165

Query: 656  RAVGVSNYGPKQLLKIHSYLASRGVPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAY 835
            +++G+SN+  + +     Y   RG  +    +Q       E    L         +L+ Y
Sbjct: 166  KSIGISNFSAQLI-----YDLIRGCTIKPVALQI------EHHPYLTQP------KLVEY 208

Query: 836  SPLGLGMLTGKYDASNLPNGPRSVLFRQILPGLESLL----SCLKSIADRKGKTMSQVAI 1003
              L    +TG Y +     GP+S L   +   L++ +      +KSIAD+ GK+ +QV +
Sbjct: 209  VQLHDIQITG-YSSF----GPQSFLEMDLKRALDTPVLLEEPTVKSIADKHGKSPAQVLL 263

Query: 1004 NWCICKGAIPIPGVKTVRHVEDNLGALGWRLSPGEISELEAAAMEC 1141
             +   +G   IP   +   +  NL  + + L+  ++  +  A ++C
Sbjct: 264  RYQTQRGIAVIPRSNSPDRMAQNLSVIDFELTQDDLQAI--AELDC 307
to top
>P52895:AK1C2_HUMAN Aldo-keto reductase family 1 member C2 - Homo sapiens (Human)|
          Length = 323

 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 73/317 (23%), Positives = 133/317 (41%), Gaps = 19/317 (5%)
 Frame = +2

Query: 230  MGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQSERLLGK 409
            +GFGT+A          E   S+  E   LA++ G +  D+A  Y        +E  +G 
Sbjct: 19   LGFGTYAPA--------EVPKSKALEAVKLAIEAGFHHIDSAHVYN-------NEEQVGL 63

Query: 410  FIRE--CQGPIKSPDDVVIATKFAAYPWRLTSGQFVN-ACRSSLERLQIDRLGIGQLHWS 580
             IR     G +K  +D+   +K  +   R    + V  A   SL+ LQ+D + +  +H+ 
Sbjct: 64   AIRSKIADGSVKR-EDIFYTSKLWSNSHR---PELVRPALERSLKNLQLDYVDLYLIHFP 119

Query: 581  TA-----NYAPLQER-----------ALWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSY 712
             +        P  E            A W+ + +  D GL +++GVSN+  + L  I + 
Sbjct: 120  VSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNK 179

Query: 713  LASRGVPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGMLTGKYDASNLPN 892
               +  P+ + QV+         Q +L   C S  + L+AYS LG        D    PN
Sbjct: 180  PGLKYKPVCN-QVECHPYF---NQRKLLDFCKSKDIVLVAYSALGSHREEPWVD----PN 231

Query: 893  GPRSVLFRQILPGLESLLSCLKSIADRKGKTMSQVAINWCICKGAIPIPGVKTVRHVEDN 1072
             P  VL       LE  + C  ++A +  +T + +A+ + + +G + +      + +  N
Sbjct: 232  SP--VL-------LEDPVLC--ALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQN 280

Query: 1073 LGALGWRLSPGEISELE 1123
            +    ++L+  E+  ++
Sbjct: 281  VQVFEFQLTSEEMKAID 297
to top
>P49378:XYL1_KLULA NAD(P)H-dependent D-xylose reductase - Kluyveromyces lactis (Yeast)|
            (Candida sphaerica)
          Length = 329

 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 67/281 (23%), Positives = 112/281 (39%), Gaps = 29/281 (10%)
 Frame = +2

Query: 320  ALKNGINLFDTADSYGTGKLNGQSERLLGKFIRECQGPIKSPDDVVIATKFAAYPWRLTS 499
            A+K G  LFD A  Y   K  GQ    + + I+E  G +K  D VV++  + ++      
Sbjct: 38   AIKIGYRLFDGAQDYANEKEVGQG---VNRAIKE--GLVKREDLVVVSKLWNSFHH---P 89

Query: 500  GQFVNACRSSLERLQIDRLGIGQLHWSTA--------NYAP-------------LQERAL 616
                 A   +L  LQ+D + I  +H+  A         Y P             ++E  +
Sbjct: 90   DNVPRALERTLSDLQLDYVDIFYIHFPLAFKPVPFDEKYPPGFYTGKEDEAKGHIEEEQV 149

Query: 617  -----WDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSYLASRGVPLSSAQVQFSLLSMGEE 781
                 W  L ++ D+G ++++G+SN+    +  +      RG  +    +Q        +
Sbjct: 150  PLLDTWRALEKLVDQGKIKSLGISNFSGALIQDL-----LRGARIKPVALQIEHHPYLTQ 204

Query: 782  QMELKTVCDSLGVRLIAYS---PLGLGMLTGKYDASNLPNGPRSVLFRQILPGLESLLSC 952
            +  +K V ++ G++++AYS   P+    L  K  A N P      LF             
Sbjct: 205  ERLIKYVKNA-GIQVVAYSSFGPVSFLELENK-KALNTPT-----LFEH---------DT 248

Query: 953  LKSIADRKGKTMSQVAINWCICKGAIPIPGVKTVRHVEDNL 1075
            +KSIA +   T  QV + W    G   IP       + DNL
Sbjct: 249  IKSIASKHKVTPQQVLLRWATQNGIAIIPKSSKKERLLDNL 289
to top
>Q95JH7:AK1C1_MACFA Aldo-keto reductase family 1 member C1 homolog - Macaca fascicularis|
            (Crab eating macaque) (Cynomolgus monkey)
          Length = 323

 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 70/317 (22%), Positives = 132/317 (41%), Gaps = 19/317 (5%)
 Frame = +2

Query: 230  MGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQSERLLGK 409
            +GFGT+A          E   ++  E   LA++ G    D+A  Y        +E  +G 
Sbjct: 19   LGFGTYAPA--------EVPKNKALEATKLAIEAGFRHIDSAHLYN-------NEEYVGL 63

Query: 410  FIRE--CQGPIKSPDDVVIATKFAAYPWRLTSGQFVN-ACRSSLERLQIDRLGIGQLHWS 580
             IR     G +K  +D+   +K      R    +FV  A   SL+ LQ+D + +  +H+ 
Sbjct: 64   AIRSKIADGTVKR-EDIFYTSKLWCNSHR---PEFVRPALERSLKNLQLDYVDLYLIHFP 119

Query: 581  TA-----NYAPLQER-----------ALWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSY 712
             +        P  E            A W+ + +  D GL +++GVSN+  +QL  I + 
Sbjct: 120  VSLKPGEELIPKDENGKLLFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNK 179

Query: 713  LASRGVPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGMLTGKYDASNLPN 892
               +  P+ +       L+    Q +L   C S  + L+A+S LG        D     N
Sbjct: 180  PGLKYKPVCNQVECHPYLN----QRKLLDFCKSKDIVLVAFSALGSHREKPWVD----QN 231

Query: 893  GPRSVLFRQILPGLESLLSCLKSIADRKGKTMSQVAINWCICKGAIPIPGVKTVRHVEDN 1072
             P  VL       LE  + C  ++A +  +T + +A+ + + +G + +      + + +N
Sbjct: 232  SP--VL-------LEDPVLC--ALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIREN 280

Query: 1073 LGALGWRLSPGEISELE 1123
            +    ++L+  ++  ++
Sbjct: 281  MKVFEFQLTSEDMKAID 297
to top
>Q95JH4:AK1C4_MACFU Aldo-keto reductase family 1 member C4 - Macaca fuscata fuscata|
            (Japanese macaque)
          Length = 323

 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 68/316 (21%), Positives = 135/316 (42%), Gaps = 18/316 (5%)
 Frame = +2

Query: 230  MGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQSERLLGK 409
            +GFG++A          E   + + E   LA++ G    D+A  Y        +E  +G 
Sbjct: 19   LGFGSYA--------PPEVPRNRVVEVTKLAIEAGFRHIDSAYLYN-------NEEQVGL 63

Query: 410  FIRE--CQGPIKSPDDVVIATKFAAYPWRLTSGQFVNACRSSLERLQIDRLGIGQLHWST 583
             IR     G +K  +D+   +K     +R    Q   A  SSL++LQ+D + +  +H+  
Sbjct: 64   AIRSKIADGSVKR-EDIFYTSKLWCTFFRPQLVQ--PALESSLKKLQLDYVDLYLIHFPM 120

Query: 584  A---NYAPLQER-------------ALWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSYL 715
            A      PL +              A+W+ + +  D GL +++GVSN+  +QL  I +  
Sbjct: 121  ALKPGETPLPKDENGKVMFDTVDLCAIWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNNP 180

Query: 716  ASRGVPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGMLTGKYDASNLPNG 895
              +  P+ +       L+    Q +L   C S  + L+A+S LG    T ++      N 
Sbjct: 181  GLKYKPVCNQVECHPYLN----QSKLLDFCKSKDIVLVAHSALG----TQRHKLWVDQNS 232

Query: 896  PRSVLFRQILPGLESLLSCLKSIADRKGKTMSQVAINWCICKGAIPIPGVKTVRHVEDNL 1075
            P           LE  + C  ++A +  ++ + +A+ + + +G + +      + + +N+
Sbjct: 233  PAL---------LEDPVLC--ALAKKHKRSPALIALRYQLQRGVVVLAKSYNEQRIRENV 281

Query: 1076 GALGWRLSPGEISELE 1123
                ++L+  ++  L+
Sbjct: 282  QVFEFQLTSEDMKVLD 297
to top
>Q8X7Z7:DKGB_ECO57 2,5-diketo-D-gluconic acid reductase B - Escherichia coli O157:H7|
          Length = 267

 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 58/281 (20%), Positives = 109/281 (38%), Gaps = 2/281 (0%)
 Frame = +2

Query: 320  ALKNGINLFDTADSYGTGKLNGQSERLLGKFIRECQGPIKSPDDVVIATKFAAYPW--RL 493
            AL+ G    DTA  Y        +E  +G  I E   P     ++ I TK     W   L
Sbjct: 25   ALELGYRAIDTAQIY-------DNEAAVGLAIAESGVP---RHELYITTKI----WIENL 70

Query: 494  TSGQFVNACRSSLERLQIDRLGIGQLHWSTANYAPLQERALWDGLVEMYDKGLVRAVGVS 673
            +  + + + + SL++L+ D + +  +HW + N     E  +   L+E   +GL R +G+S
Sbjct: 71   SKDKLIPSLKESLQKLRTDYVDLTLIHWPSPNDEVSVEEFM-QALLEAKKEGLTREIGIS 129

Query: 674  NYGPKQLLKIHSYLASRGVPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLG 853
            N+    + K  + + +  +  +  +     LS   +  ++       G+ + +Y  L  G
Sbjct: 130  NFTIPLMEKAIAAVGAENIATNQIE-----LSPYLQNRKVVAWAKQHGIHITSYMTLAYG 184

Query: 854  MLTGKYDASNLPNGPRSVLFRQILPGLESLLSCLKSIADRKGKTMSQVAINWCICKGAIP 1033
                                             +  IA +   T +QV + W + +G   
Sbjct: 185  KALKD--------------------------EVIARIAAKHNATPAQVILAWAMGEGYSV 218

Query: 1034 IPGVKTVRHVEDNLGALGWRLSPGEISELEAAAMECPKKMV 1156
            IP      ++E NL A   +L   +   +  AA++C  ++V
Sbjct: 219  IPSSTKRENLESNLKAQNLQLDAEDKKAI--AALDCNDRLV 257
to top
>O95154:ARK73_HUMAN Aflatoxin B1 aldehyde reductase member 3 - Homo sapiens (Human)|
          Length = 331

 Score = 45.1 bits (105), Expect = 7e-04
 Identities = 66/277 (23%), Positives = 108/277 (38%), Gaps = 24/277 (8%)
 Frame = +2

Query: 323  LKNGINLFDTADSYGTGKLNGQSERLLGKFIRECQGPIKSPDDVVIATK-FAAYPWRLTS 499
            L+ G    DTA  Y      GQSE +LG       G   S   V I TK    +   L  
Sbjct: 36   LERGHTEIDTAFVYS----EGQSETILGGLGLRLGG---SDCRVKIDTKAIPLFGNSLKP 88

Query: 500  GQFVNACRSSLERLQIDRLGIGQLHWSTANYAPLQERALWDGLVEMYDKGLVRAVGVSNY 679
                    +SL+RLQ  R+ +  LH    +  P++E        +++ +G    +G+SNY
Sbjct: 89   DSLRFQLETSLKRLQCPRVDLFYLHMPDHS-TPVEETLR--ACHQLHQEGKFVELGLSNY 145

Query: 680  GPKQLLKIHSYLASRGVPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGML 859
               ++ +I +   S G  L +           + + EL       G+R  A++PL  G+L
Sbjct: 146  AAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNPLAGGLL 205

Query: 860  TGKYDASNLPNGPRSV----------LFR------QILPGLESLLSCLKSIADRKGKTMS 991
            TGKY   +  NG + V          ++R          G+  +   L++       +M+
Sbjct: 206  TGKYKYED-KNGKQPVGRFFGNTWAEMYRNRYWKEHHFEGIALVEKALQAAYGASAPSMT 264

Query: 992  QVAINWCI-------CKGAIPIPGVKTVRHVEDNLGA 1081
               + W           G   I G+ ++  +E NL A
Sbjct: 265  SATLRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLAA 301
to top
>P51652:AKC1H_RAT Aldo-keto reductase family 1 member C18 - Rattus norvegicus (Rat)|
          Length = 323

 Score = 44.7 bits (104), Expect = 9e-04
 Identities = 69/321 (21%), Positives = 136/321 (42%), Gaps = 19/321 (5%)
 Frame = +2

Query: 218  SVSPMGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQSER 397
            S+  +GFGT+A         EE++  +  E   +A+  G    D +  Y       Q+E 
Sbjct: 15   SIPVLGFGTYAT--------EENLRKKSMESTKIAIDVGFRHIDCSHLY-------QNEE 59

Query: 398  LLGKFI--RECQGPIKSPDDVVIATKFAAYPWRLTSGQFVN-ACRSSLERLQIDRLGIGQ 568
             +G+ I  +   G +K  +D+   +K  +   R    + V  +  +SL +L +D + +  
Sbjct: 60   EIGQAIVSKIEDGTVKR-EDIFYTSKLWSTSHR---PELVRPSLENSLRKLNLDYVDLYL 115

Query: 569  LHWSTA-----NYAPLQERA-----------LWDGLVEMYDKGLVRAVGVSNYGPKQLLK 700
            +H+  +        P  E              W+ + +  D GL +++GVSN+  +QL K
Sbjct: 116  IHFPVSLKPGDELLPQDEHGNLILDTVDLCDTWEAMEKCKDAGLAKSIGVSNFNRRQLEK 175

Query: 701  IHSYLASRGVPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGMLTGKYDAS 880
            I +    +  P+ + QV+  L      Q +L   C    + L+AY  LG    T +Y   
Sbjct: 176  ILNKPGLKHRPVCN-QVECHLYL---NQSKLLAYCKMNDIVLVAYGALG----TQRY--K 225

Query: 881  NLPNGPRSVLFRQILPGLESLLSCLKSIADRKGKTMSQVAINWCICKGAIPIPGVKTVRH 1060
               N    VL       L+  + C  ++A +  +T + +A+ + + +G + +        
Sbjct: 226  YCINEDTPVL-------LDDPILC--TMAKKYKRTPALIALRYQLERGIVTLVKSFNEER 276

Query: 1061 VEDNLGALGWRLSPGEISELE 1123
            + +NL    ++L+  ++  L+
Sbjct: 277  IRENLQVFDFQLASDDMEILD 297
to top
>O74237:XYL1_CANTE NAD(P)H-dependent D-xylose reductase - Candida tenuis (Yeast)|
          Length = 322

 Score = 44.3 bits (103), Expect = 0.001
 Identities = 70/309 (22%), Positives = 116/309 (37%), Gaps = 28/309 (9%)
 Frame = +2

Query: 197  KVNVGPLSVSPMGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGK 376
            K++ G L  S +GFG W   N           +   E    A+K G  LFD A+ YG  K
Sbjct: 9    KLSSGHLMPS-IGFGCWKLAN-----------ATAGEQVYQAIKAGYRLFDGAEDYGNEK 56

Query: 377  LNGQSERLLGKFIRECQGPIKSPDDVVIATKFAAYPWR--LTSGQFVNACRSSLERLQID 550
              G   +      R     +   +++ + +K     W           A   +L  L++D
Sbjct: 57   EVGDGVK------RAIDEGLVKREEIFLTSKL----WNNYHDPKNVETALNKTLADLKVD 106

Query: 551  RLGIGQLHWSTA-NYAPLQER---------------------ALWDGLVEMYDKGLVRAV 664
             + +  +H+  A  + P++E+                       W  L ++   G ++++
Sbjct: 107  YVDLFLIHFPIAFKFVPIEEKYPPGFYCGDGNNFVYEDVPILETWKALEKLVAAGKIKSI 166

Query: 665  GVSNYGPKQLLKIHSYLASRGVPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPL 844
            GVSN+    LL +      RG  +  A +Q        +Q +L       GV + AYS  
Sbjct: 167  GVSNFPGALLLDL-----LRGATIKPAVLQVEHHPY-LQQPKLIEFAQKAGVTITAYSSF 220

Query: 845  G----LGMLTGKYDASNLPNGPRSVLFRQILPGLESLLSCLKSIADRKGKTMSQVAINWC 1012
            G    + M  G+  A N P      LF             +K+IA +  KT ++V + W 
Sbjct: 221  GPQSFVEMNQGR--ALNTP-----TLFAH---------DTIKAIAAKYNKTPAEVLLRWA 264

Query: 1013 ICKGAIPIP 1039
              +G   IP
Sbjct: 265  AQRGIAVIP 273
to top
>Q5R7C9:AK1C3_PONPY Aldo-keto reductase family 1 member C3 homolog - Pongo pygmaeus|
            (Orangutan)
          Length = 323

 Score = 43.9 bits (102), Expect = 0.001
 Identities = 70/318 (22%), Positives = 134/318 (42%), Gaps = 20/318 (6%)
 Frame = +2

Query: 230  MGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQSERLLGK 409
            +GFGT+A          E   S+  E   LA++ G    D+A  Y        +E  +G 
Sbjct: 19   LGFGTYA--------PPEVPRSKALEVTKLAIEAGFRHIDSAHLYN-------NEEQVGL 63

Query: 410  FIRE--CQGPIKSPDDVVIATKFAAYPWRLTSGQFVN-ACRSSLERLQIDRLGIGQLHWS 580
             IR     G +K  D    +  ++ +       + V  A  +SL++ Q+D + +  +H S
Sbjct: 64   AIRSKIADGSVKREDIFYTSKLWSTFH----RPELVRPALENSLKKAQLDYVDLYLIH-S 118

Query: 581  TANYAPLQERA-----------------LWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHS 709
              +  P +E +                  W+ + E  D GL +++GVSN+  +QL  I +
Sbjct: 119  PMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEECKDAGLAKSIGVSNFNRRQLEMILN 178

Query: 710  YLASRGVPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGMLTGKYDASNLP 889
                +  P+ + QV+         + +L   C S  + L+AYS LG        D    P
Sbjct: 179  KPGLKYKPVCN-QVECHPYF---NRSKLLDFCKSKDIVLVAYSALGSQRDKRWVD----P 230

Query: 890  NGPRSVLFRQILPGLESLLSCLKSIADRKGKTMSQVAINWCICKGAIPIPGVKTVRHVED 1069
            N P  VL       LE  + C  ++A +  +T + +A+ + + +G + +      + + +
Sbjct: 231  NSP--VL-------LEDPVLC--ALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRE 279

Query: 1070 NLGALGWRLSPGEISELE 1123
            N+    ++L+  ++  ++
Sbjct: 280  NVQVFEFQLTAEDMRAID 297
to top
>Q01752:AAD_PHACH Aryl-alcohol dehydrogenase [NADP+] - Phanerochaete chrysosporium|
            (White-rot fungus) (Sporotrichum pruinosum)
          Length = 385

 Score = 43.5 bits (101), Expect = 0.002
 Identities = 80/328 (24%), Positives = 148/328 (45%), Gaps = 26/328 (7%)
 Frame = +2

Query: 215  LSVSPMGFGTWAWGNQLLWGYEESMDSELQECFNLALKN-GINLFDTADSYGTGKLNGQS 391
            L VSP+  G  + G++       +MD E       A  N G N  DTA+ Y     +  S
Sbjct: 26   LHVSPIQLGAMSIGDKWHPYGMGTMDKEASFKLLDAFYNAGGNFIDTANVYQ----DETS 81

Query: 392  ERLLGKFIRECQGPIKSPDDVVIATKFAAYPWRLTSGQFV--------NACRS------- 526
            E  +G+++ E +G   + D +V+ATK++    R  S + +        N+ +S       
Sbjct: 82   EEFIGEWM-EARG---NRDQMVVATKYSLVYKRGASFEEIPQKTQYVGNSLKSMHISVHD 137

Query: 527  SLERLQIDRLGIGQLHWSTANYAPLQERALWDGLVEMYDKGLVRAVGVSNYGPKQLLKIH 706
            SL +L+   + I  +H+   +Y    E  + +GL  +  +G V  +GVS+     + K +
Sbjct: 138  SLRKLRTSYIDIFYVHFW--DYTCTIEEVM-NGLHNLVAQGKVLYLGVSDTPAWVVSKAN 194

Query: 707  SYLASRG-VPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGML-TGKYDAS 880
            +Y    G  P    + ++++ +M + + ++  +C   G+ +  ++ L  G + T   +  
Sbjct: 195  NYARMAGKTPFVIYEGEWNI-TMRDMERDIIPMCIHEGMAIAPWNVLCAGKIRTDAEEER 253

Query: 881  NLPNGPRSVLFRQILPGLES-----LLSCLKSIADRKG-KTMSQVAINWCICKG--AIPI 1036
             L +G       Q    L +     +   L+ +A+  G K+++ VAI + + K     PI
Sbjct: 254  RLKSGEGGRTLLQFDGWLRNETERKVSKALEKVAEEIGAKSITSVAIAYLMQKFPYVFPI 313

Query: 1037 PGVKTVRHVEDNLGALGWRLSPGEISEL 1120
             G + V H+  NL AL   LSP ++  L
Sbjct: 314  VGGRKVEHLYANLEALDISLSPEQMQFL 341
to top
>Q10494:YDG7_SCHPO Probable oxidoreductase C26F1.07 - Schizosaccharomyces pombe (Fission|
            yeast)
          Length = 321

 Score = 42.7 bits (99), Expect = 0.003
 Identities = 67/309 (21%), Positives = 117/309 (37%), Gaps = 28/309 (9%)
 Frame = +2

Query: 230  MGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQSERLLGK 409
            +G GTW            S  ++ +     AL+ G    D A  YG       +E  +G 
Sbjct: 27   LGLGTW-----------RSEPNQTKNAVKTALQYGYRHIDAAAIYG-------NEDEVGD 68

Query: 410  FIRECQGPIKSPDDVVIATKF---AAYPWRLTSGQFVNACRSSLERLQIDRLGIGQLHWS 580
             I+E   P K   D+ + +K    A  P  +       A   +L+ L++D L    +HW 
Sbjct: 69   GIKESGVPRK---DIWVTSKLWCNAHAPEAVPK-----ALEKTLKDLKLDYLDEYLIHWP 120

Query: 581  TA------------------NYAPLQERALWDGLVEMYDKGLVRAVGVSNYGPKQLLKIH 706
             +                     P++E   W  + ++ + G VR +G+SN+    L +I 
Sbjct: 121  VSFKTGEDKFPKDKDGNLIYEKNPIEET--WKAMEKLLETGKVRHIGLSNFNDTNLERI- 177

Query: 707  SYLASRGVPLSSAQVQFSLLSMGEE----QMELKTVCDSLGVRLIAYSPLGLGMLTGKYD 874
                     L  A+V+ ++  M       Q E       LG+ + AYSP           
Sbjct: 178  ---------LKVAKVKPAVHQMELHPFLPQTEFVEKHKKLGIHVTAYSPF---------- 218

Query: 875  ASNLPNGPRSVLFRQILPGL---ESLLSCLKSIADRKGKTMSQVAINWCICKGAIPIPGV 1045
                  G ++ ++   +P L   E++    KS  +  G T + +A++W I +G   IP  
Sbjct: 219  ------GNQNTIYESKIPKLIEHETIQKIAKSKGE--GVTGATIAVSWAITRGTSVIPKS 270

Query: 1046 KTVRHVEDN 1072
               + ++ N
Sbjct: 271  VNEQRIKSN 279
to top
>Q07551:KAR_YEAST NADPH-dependent alpha-keto amide reductase - Saccharomyces cerevisiae|
            (Baker's yeast)
          Length = 312

 Score = 42.4 bits (98), Expect = 0.004
 Identities = 35/175 (20%), Positives = 71/175 (40%), Gaps = 1/175 (0%)
 Frame = +2

Query: 617  WDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSYLASRGVPLSSAQVQFSLLSMGEEQMELK 796
            W  + ++Y  G  + +GVSN+  + L +I   L    V     Q++FS     +     K
Sbjct: 139  WKDMEQLYKSGKAKNIGVSNFAVEDLQRI---LKVAEVKPQVNQIEFSPFLQNQTPGIYK 195

Query: 797  TVCDSLGVRLIAYSPLG-LGMLTGKYDASNLPNGPRSVLFRQILPGLESLLSCLKSIADR 973
              C    + + AYSPLG L   T + D+                   +     +K ++++
Sbjct: 196  -FCQEHDILVEAYSPLGPLQKKTAQDDS-------------------QPFFEYVKELSEK 235

Query: 974  KGKTMSQVAINWCICKGAIPIPGVKTVRHVEDNLGALGWRLSPGEISELEAAAME 1138
              K+ +Q+ + W   +G +P+      + + D      + L+  E+ ++    +E
Sbjct: 236  YIKSEAQIILRWVTKRGVLPVTTSSKPQRISDAQNLFSFDLTAEEVDKITELGLE 290
to top
>P42330:AK1C3_HUMAN Aldo-keto reductase family 1 member C3 - Homo sapiens (Human)|
          Length = 323

 Score = 42.0 bits (97), Expect = 0.006
 Identities = 69/318 (21%), Positives = 133/318 (41%), Gaps = 20/318 (6%)
 Frame = +2

Query: 230  MGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQSERLLGK 409
            +GFGT+A          E   S+  E   LA++ G    D+A  Y        +E  +G 
Sbjct: 19   LGFGTYA--------PPEVPRSKALEVTKLAIEAGFRHIDSAHLYN-------NEEQVGL 63

Query: 410  FIRE--CQGPIKSPDDVVIATKFAAYPWRLTSGQFVN-ACRSSLERLQIDRLGIGQLHWS 580
             IR     G +K  D    +  ++ +       + V  A  +SL++ Q+D + +  +H S
Sbjct: 64   AIRSKIADGSVKREDIFYTSKLWSTFH----RPELVRPALENSLKKAQLDYVDLYLIH-S 118

Query: 581  TANYAPLQERA-----------------LWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHS 709
              +  P +E +                  W+ + +  D GL +++GVSN+  +QL  I +
Sbjct: 119  PMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILN 178

Query: 710  YLASRGVPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGMLTGKYDASNLP 889
                +  P+ + QV+         + +L   C S  + L+AYS LG        D    P
Sbjct: 179  KPGLKYKPVCN-QVECHPYF---NRSKLLDFCKSKDIVLVAYSALGSQRDKRWVD----P 230

Query: 890  NGPRSVLFRQILPGLESLLSCLKSIADRKGKTMSQVAINWCICKGAIPIPGVKTVRHVED 1069
            N P  VL       LE  + C  ++A +  +T + +A+ + + +G + +      + +  
Sbjct: 231  NSP--VL-------LEDPVLC--ALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQ 279

Query: 1070 NLGALGWRLSPGEISELE 1123
            N+    ++L+  ++  ++
Sbjct: 280  NVQVFEFQLTAEDMKAID 297
to top
>P42972:YCSN_BACSU Uncharacterized oxidoreductase ycsN - Bacillus subtilis|
          Length = 300

 Score = 41.6 bits (96), Expect = 0.007
 Identities = 48/208 (23%), Positives = 82/208 (39%), Gaps = 13/208 (6%)
 Frame = +2

Query: 269 WGYEESMDSELQECFNLALKNGINLFDTADSYG---TGKLNGQSERLLG------KFIRE 421
           W Y    D+EL       + +GI  FD AD YG     KL G +  L        + + +
Sbjct: 25  WNYS---DAELLSLIEWCIDHGITTFDHADIYGGYTCEKLFGNALALSPGLRENIELVTK 81

Query: 422 CQGPIKSPDDVVIATKFAAYPWRLTSGQFVNACRSSLERLQIDRLGIGQLHWSTANYAPL 601
           C   ++SP+         ++ +  +    + +   SL  L+ D + +  +H       P 
Sbjct: 82  CGIVLESPE----RPAHRSHHYNTSKSHILASVEQSLMNLRTDYIDMLLIHRPDPLMDP- 136

Query: 602 QERALWDGLVEMYD----KGLVRAVGVSNYGPKQLLKIHSYLASRGVPLSSAQVQFSLLS 769
                 +G+ E +      G VR  GVSN+   Q   + SYL  +   L + Q++ S   
Sbjct: 137 ------EGVAEAFQALKCSGKVRYFGVSNFKDHQYRMLESYLPEK---LVTNQIELSAYE 187

Query: 770 MGEEQMELKTVCDSLGVRLIAYSPLGLG 853
           +         +C    +  +A+SPL  G
Sbjct: 188 LENMLDGTLNLCQEKRIPPMAWSPLAGG 215
to top
>Q01213:DTDH_MUCMU 4-dihydromethyl-trisporate dehydrogenase - Mucor mucedo|
          Length = 321

 Score = 40.8 bits (94), Expect = 0.013
 Identities = 72/322 (22%), Positives = 122/322 (37%), Gaps = 24/322 (7%)
 Frame = +2

Query: 233  GFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQSERLLGKF 412
            GFG W    +           + +E    A+K G  LFD A  YG     G+    + K 
Sbjct: 19   GFGCWKIDTK-----------DCEETVYQAIKTGYRLFDGACDYGNEVEVGRG---INKA 64

Query: 413  IRECQGPIKSPDDVVIATKFAAYPWR-LTSGQFVNACRS-SLERLQIDRLGIGQLH---- 574
            I E  G +K  +D+ I TK     W    S + V A     L+   ++   +  +H    
Sbjct: 65   INE--GLVKR-EDLFIVTKL----WNTFHSKKHVRALFDRQLKDTGLEYFDLYLIHFPVP 117

Query: 575  -------------WSTANYAPLQERA-----LWDGLVEMYDKGLVRAVGVSNYGPKQLLK 700
                         W   +   LQ         W  L ++ D GL R +GV+N+  + +L 
Sbjct: 118  LQYVDPATVYPPGWYVGDAKSLQFEQSPIHECWAELEKIVDAGLARNIGVANFNCQAILD 177

Query: 701  IHSYLASRGVPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGMLTGKYDAS 880
            + +Y       +  A +Q  L     ++  +K V +  G+++ AYS  G    T   D +
Sbjct: 178  LLTYAR-----IKPAVLQIELHPYLPQERLVKWVKEQ-GIQITAYSSFGP---TSYVDLT 228

Query: 881  NLPNGPRSVLFRQILPGLESLLSCLKSIADRKGKTMSQVAINWCICKGAIPIPGVKTVRH 1060
                   S+L            + +KS+AD+   +  QV + W + +    IP       
Sbjct: 229  ESGKTYTSLLEH----------ASVKSVADKHNVSTGQVLLRWALDREFAVIPKSVNAGR 278

Query: 1061 VEDNLGALGWRLSPGEISELEA 1126
            ++ NL  L  +L   +   L++
Sbjct: 279  MKANLEILDIKLDAEDNKTLDS 300
to top
>Q8ZRM7:DKGB_SALTY 2,5-diketo-D-gluconic acid reductase B - Salmonella typhimurium|
          Length = 267

 Score = 40.8 bits (94), Expect = 0.013
 Identities = 56/281 (19%), Positives = 111/281 (39%), Gaps = 2/281 (0%)
 Frame = +2

Query: 320  ALKNGINLFDTADSYGTGKLNGQSERLLGKFIRECQGPIKSPDDVVIATKFAAYPW--RL 493
            AL+ G    DTA  Y        +E  +G+ I E   P    +++ I TK     W   L
Sbjct: 25   ALELGYRAVDTAQIY-------DNEAAVGQAIAESGVP---RNELYITTKI----WIENL 70

Query: 494  TSGQFVNACRSSLERLQIDRLGIGQLHWSTANYAPLQERALWDGLVEMYDKGLVRAVGVS 673
            +  + + + + SL++L+ D + +  +HW +   A   E  +   L+E   +GL R +G+S
Sbjct: 71   SKDKLIPSLKESLKKLRTDYVDLTLIHWPSPGDAVSVEEFM-QALLEAKKQGLTREIGIS 129

Query: 674  NYGPKQLLKIHSYLASRGVPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLG 853
            N+    + K  + + +  +  +  +     LS   +  ++     + G+ + +Y  L  G
Sbjct: 130  NFTIPLMEKAIAAVGADNIATNQIE-----LSPYLQNRKVVDWAKAHGIHITSYMTLAYG 184

Query: 854  MLTGKYDASNLPNGPRSVLFRQILPGLESLLSCLKSIADRKGKTMSQVAINWCICKGAIP 1033
                                             +  IA +   T +QV + W + +G   
Sbjct: 185  KALKD--------------------------EVIARIAAKHNATPAQVILAWAMGEGYSV 218

Query: 1034 IPGVKTVRHVEDNLGALGWRLSPGEISELEAAAMECPKKMV 1156
            IP      ++  +L A    L   + + +  AA++C  ++V
Sbjct: 219  IPSSTRRENLASSLLAQDLHLDAEDKNAI--AALDCNDRLV 257
to top
>Q8Z988:DKGB_SALTI 2,5-diketo-D-gluconic acid reductase B - Salmonella typhi|
          Length = 267

 Score = 40.8 bits (94), Expect = 0.013
 Identities = 58/282 (20%), Positives = 113/282 (40%), Gaps = 3/282 (1%)
 Frame = +2

Query: 320  ALKNGINLFDTADSYGTGKLNGQSERLLGKFIRECQGPIKSPDDVVIATKFAAYPW--RL 493
            AL+ G    DTA  Y        +E  +G+ I E   P    +++ I TK     W   L
Sbjct: 25   ALELGYRAVDTAQIY-------DNEAAVGQAIAESGVP---RNELYITTKI----WIENL 70

Query: 494  TSGQFVNACRSSLERLQIDRLGIGQLHWSTANYAPLQERALWDGLVEMYDKGLVRAVGVS 673
            +  + + + + SL++L+ D + +  +HW +   A   E  +   L+E   +GL R +G+S
Sbjct: 71   SKDKLIPSLKESLKKLRTDYVDLTLIHWPSPGDAVSVEEFM-QALLEAKKQGLTREIGIS 129

Query: 674  NYGPKQLLKIHSYLASRGVP-LSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGL 850
            N+    +  +   +A+ G   +++ Q++ S      + ++      + G+ + +Y  L  
Sbjct: 130  NF---TIPLMEKAIAAVGADHIATNQIELSPYLQNRKVVDW---AKAHGIHITSYMTLAY 183

Query: 851  GMLTGKYDASNLPNGPRSVLFRQILPGLESLLSCLKSIADRKGKTMSQVAINWCICKGAI 1030
            G                                 +  IA +   T  QV + W + +G  
Sbjct: 184  GKALKD--------------------------EVIARIAVKHNATPVQVILAWAMGEGYS 217

Query: 1031 PIPGVKTVRHVEDNLGALGWRLSPGEISELEAAAMECPKKMV 1156
             IP      ++  NL A    L   + + +  AA++C  ++V
Sbjct: 218  VIPSSTRRENLASNLLAQDLHLDAEDKNAI--AALDCNDRLV 257
to top
>P23457:DIDH_RAT 3-alpha-hydroxysteroid dehydrogenase - Rattus norvegicus (Rat)|
          Length = 322

 Score = 40.8 bits (94), Expect = 0.013
 Identities = 65/317 (20%), Positives = 131/317 (41%), Gaps = 19/317 (5%)
 Frame = +2

Query: 230  MGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQSERLLGK 409
            +GFGT           E+    E+ +   +A+ NG   FD+A  Y       + E  +G+
Sbjct: 19   LGFGTTV--------PEKVAKDEVIKATKIAIDNGFRHFDSAYLY-------EVEEEVGQ 63

Query: 410  FIREC--QGPIKSPDDVVIATKFAAYPWRLTSGQFVNAC-RSSLERLQIDRLGIGQLHWS 580
             IR     G +K  D    +  ++ +       + V  C   +L+  Q+D + +  +H+ 
Sbjct: 64   AIRSKIEDGTVKREDIFYTSKLWSTFH----RPELVRTCLEKTLKSTQLDYVDLYIIHFP 119

Query: 581  TAN-----YAPLQERA-----------LWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSY 712
             A      + P  E              W+ + +  D GL +++GVSN+  +QL +I + 
Sbjct: 120  MALQPGDIFFPRDEHGKLLFETVDICDTWEAMEKCKDAGLAKSIGVSNFNCRQLERILNK 179

Query: 713  LASRGVPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGMLTGKYDASNLPN 892
               +  P+ + QV+  L      Q ++   C S  + L++Y  LG        D  +   
Sbjct: 180  PGLKYKPVCN-QVECHLYL---NQSKMLDYCKSKDIILVSYCTLGSSRDKTWVDQKS--- 232

Query: 893  GPRSVLFRQILPGLESLLSCLKSIADRKGKTMSQVAINWCICKGAIPIPGVKTVRHVEDN 1072
                VL       L+  + C  +IA +  +T + VA+ + + +G +P+      + +++ 
Sbjct: 233  ---PVL-------LDDPVLC--AIAKKYKQTPALVALRYQLQRGVVPLIRSFNAKRIKEL 280

Query: 1073 LGALGWRLSPGEISELE 1123
                 ++L+  ++  L+
Sbjct: 281  TQVFEFQLASEDMKALD 297
to top
>Q8K023:AKC1H_MOUSE Aldo-keto reductase family 1 member C18 - Mus musculus (Mouse)|
          Length = 323

 Score = 40.8 bits (94), Expect = 0.013
 Identities = 67/319 (21%), Positives = 133/319 (41%), Gaps = 17/319 (5%)
 Frame = +2

Query: 218  SVSPMGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQSER 397
            S+  +GFGT+A         EE +  +  E   +A+  G    D +  Y   +  GQ+  
Sbjct: 15   SIPVLGFGTYAT--------EEHLKKKSMESTKIAIDVGFCHIDCSHLYQNEEEIGQA-- 64

Query: 398  LLGKFIRECQGPIKSPDDVVIATKFAAYPWRLTSGQFVN-ACRSSLERLQIDRLGIGQLH 574
            +L K      G +K  +D+   +K  +   R    + V  +  +SL +L +D + +  +H
Sbjct: 65   ILSKIE---DGTVKR-EDIFYTSKLWSTSHR---PELVRPSLENSLRKLNLDYVDLYLIH 117

Query: 575  WSTA-----NYAPLQERA-----------LWDGLVEMYDKGLVRAVGVSNYGPKQLLKIH 706
            +  +        P  E              W+ + +  D GL +++GVSN+  +QL  I 
Sbjct: 118  FPVSLKPGNELLPKDEHGNLIFDTVDLCDTWEAMEKCKDAGLAKSIGVSNFNRRQLEMIL 177

Query: 707  SYLASRGVPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGMLTGKYDASNL 886
            +    +  P+ + QV+  L      Q +L   C    + L+AY  LG    T +Y     
Sbjct: 178  NKPGLKYKPVCN-QVECHLYL---NQSKLLAYCKMNDIVLVAYGALG----TQRY--KYC 227

Query: 887  PNGPRSVLFRQILPGLESLLSCLKSIADRKGKTMSQVAINWCICKGAIPIPGVKTVRHVE 1066
             N    VL       L+  + C  ++A +  +T + +A+ + + +G + +        + 
Sbjct: 228  INEDTPVL-------LDDPVLC--AMAKKYKRTPALIALRYQLDRGIVALAKSFNEERIR 278

Query: 1067 DNLGALGWRLSPGEISELE 1123
            +N+    ++L+  ++  L+
Sbjct: 279  ENMQVFDFQLASDDMKILD 297
to top
>P38115:ARA1_YEAST D-arabinose dehydrogenase [NAD(P)+] heavy chain - Saccharomyces|
            cerevisiae (Baker's yeast)
          Length = 344

 Score = 38.9 bits (89), Expect = 0.048
 Identities = 73/323 (22%), Positives = 127/323 (39%), Gaps = 31/323 (9%)
 Frame = +2

Query: 293  SELQECFNLALKNGINLFDTADSYGTGKLNGQSERLLGKFIREC--QGPIKSPDDVVIAT 466
            +E ++    A+K G    DTA +Y T       E  +G+ I+E    G IK  +D+ I T
Sbjct: 48   AETKQAVKAAIKAGYRHIDTAWAYET-------EPFVGEAIKELLEDGSIKR-EDLFITT 99

Query: 467  KFAAYPWRLTSGQFVNACRSSLERLQIDRLGIGQLHWSTANYAPLQERALWDGLVE---- 634
            K     W +   +   +   SL+ L ++ + +   HW    +  +++     GLV+    
Sbjct: 100  KV----WPVLWDEVDRSLNESLKALGLEYVDLLLQHWPLC-FEKIKDPKGISGLVKTPVD 154

Query: 635  -----MY--------------------DKGLVRAVGVSNYGPKQLLKIHSYLASRGVPLS 739
                 MY                    +   VRA+GVSN+  + L ++   +    V  +
Sbjct: 155  DSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLERL---IKECRVKPT 211

Query: 740  SAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGMLTGKYDASNLPNGPRSVLFRQ 919
              QV+         QMEL+  C    + L AYSPL      G + A NL           
Sbjct: 212  VNQVE---THPHLPQMELRKFCFMHDILLTAYSPL------GSHGAPNLK---------- 252

Query: 920  ILPGLESLLSCLKSIADRKGKTMSQVAINWCICKGAIPIPGVKTVRHVEDNLGALGWRLS 1099
                    +  +K +A++   T + + I++ I +G I IP  +++  V  +       L+
Sbjct: 253  --------IPLVKKLAEKYNVTGNDLLISYHIRQGTIVIP--RSLNPVRISSSIEFASLT 302

Query: 1100 PGEISELEAAAMECPKKMVQNIF 1168
              E+ EL     + P + +   F
Sbjct: 303  KDELQELNDFGEKYPVRFIDEPF 325
to top
>Q01333:YCR4_ESCVU Hypothetical 11.2 kDa protein in crtE 3'region - Escherichia|
           vulneris
          Length = 103

 Score = 37.4 bits (85), Expect = 0.14
 Identities = 24/69 (34%), Positives = 33/69 (47%), Gaps = 3/69 (4%)
 Frame = +2

Query: 215 LSVSPMGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGT---GKLNG 385
           L + P+ FG    GN   W  +E     L +     L+ G+N  DTAD Y     G   G
Sbjct: 11  LHIPPLVFG----GNVFGWTVDEQQSFSLLDAL---LERGLNAIDTADVYSAWAPGNKGG 63

Query: 386 QSERLLGKF 412
           +SE +LGK+
Sbjct: 64  ESETILGKW 72
to top
>P38715:GRE3_YEAST NADPH-dependent aldose reductase GRE3 - Saccharomyces cerevisiae|
            (Baker's yeast)
          Length = 327

 Score = 37.0 bits (84), Expect = 0.18
 Identities = 62/273 (22%), Positives = 99/273 (36%), Gaps = 33/273 (12%)
 Frame = +2

Query: 320  ALKNGINLFDTADSYGTGKLNGQSERLLGKFIRECQGPIKSPDDVVIATKFAAYPWR--L 493
            A+K G  LFD A  YG  K  G+  R   K I E    + S  D+ + +K     W    
Sbjct: 35   AIKLGYRLFDGACDYGNEKEVGEGIR---KAISE---GLVSRKDIFVVSKL----WNNFH 84

Query: 494  TSGQFVNACRSSLERLQIDRLGIGQLHWSTA-NYAPLQER-------------------- 610
                   A + +L  + +D L +  +H+  A  Y P +E+                    
Sbjct: 85   HPDHVKLALKKTLSDMGLDYLDLYYIHFPIAFKYVPFEEKYPPGFYTGADDEKKGHITEA 144

Query: 611  -----ALWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSYLASRGVPLSSAQVQFSLLSMG 775
                   +  L E  D+GL++++GVSN+   Q   I   L    +   + Q++       
Sbjct: 145  HVPIIDTYRALEECVDEGLIKSIGVSNF---QGSLIQDLLRGCRIKPVALQIEHHPYLTQ 201

Query: 776  EEQMELKTVCDSLGVRLIAYSPLGLGMLTGKYDASNLPNGPRSVL-----FRQILPGLES 940
            E  +E    C    ++++AYS                  GP+S +       +  P L  
Sbjct: 202  EHLVEF---CKLHDIQVVAYSSF----------------GPQSFIEMDLQLAKTTPTLFE 242

Query: 941  LLSCLKSIADRKGKTMSQVAINWCICKGAIPIP 1039
                 K   +  G T SQV + W   +G   IP
Sbjct: 243  NDVIKKVSQNHPGSTTSQVLLRWATQRGIAVIP 275
to top
>P78736:XYL1_PACTA NAD(P)H-dependent D-xylose reductase - Pachysolen tannophilus (Yeast)|
          Length = 318

 Score = 36.2 bits (82), Expect = 0.31
 Identities = 56/262 (21%), Positives = 100/262 (38%), Gaps = 22/262 (8%)
 Frame = +2

Query: 320  ALKNGINLFDTADSYGTGKLNGQSERLLGKFIRECQGPIKSPDDVVIATKFAAYPWRLTS 499
            A+K G  LFD A  YG  K  G+    + + I++  G +K  D  + +  +  +      
Sbjct: 34   AIKEGYRLFDCACDYGNEKEVGEG---INRAIKD--GLVKRKDLFITSKLWNNFH---AK 85

Query: 500  GQFVNACRSSLERLQIDRLGIGQLHWSTA-NYAPLQER---------------------A 613
                 A   SL    +D   +  +H+  +  + P +E+                      
Sbjct: 86   ENVKKALMKSLSDFNLDYFDLYLMHFPISFKFVPFEEKYPPGFYCGDGDKFIYEDVPIIE 145

Query: 614  LWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSYLASRGVPLSSAQVQFSLLSMGEEQMEL 793
             W  +  + D+GLV+++GVSN     L      + +  +  +S Q++        +Q +L
Sbjct: 146  TWRAMENLVDEGLVKSIGVSNVSGGLL---EDLIKAARIKPASLQIEHHPYL---QQNKL 199

Query: 794  KTVCDSLGVRLIAYSPLGLGMLTGKYDASNLPNGPRSVLFRQILPGLESLLSCLKSIADR 973
                   G+ +  YS  G          S L  G  +   ++  P  E+    + +IA +
Sbjct: 200  VEYAQLKGIVVTGYSNFG--------PLSFLELGNETA--KKTQPLYEN--KTITTIAAK 247

Query: 974  KGKTMSQVAINWCICKGAIPIP 1039
             GKT  QV + W   +G   IP
Sbjct: 248  HGKTPFQVLLRWVNQRGIAIIP 269
to top
>Q5T2L2:AKCL1_HUMAN Aldo-keto reductase family 1 member C-like protein 1 - Homo sapiens|
            (Human)
          Length = 302

 Score = 34.3 bits (77), Expect = 1.2
 Identities = 70/326 (21%), Positives = 129/326 (39%), Gaps = 17/326 (5%)
 Frame = +2

Query: 197  KVNVGPLSVSPMGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGK 376
            ++N GP  +  +GFGT+A         + +  S+  E   +A+  G    D+A  Y    
Sbjct: 12   RLNDGPF-MPVLGFGTYA--------PDHTPKSQAAEATKVAIDVGFRHIDSAYLY---- 58

Query: 377  LNGQSERLLGKFIRE--CQGPIKSPDDVVIATKFAAYPWRLTSGQFVN-ACRSSLERLQI 547
               Q+E  +G+ I E    G +K  +++    K  A  +R    + V+ A   SL++L  
Sbjct: 59   ---QNEEEVGQAIWEKIADGTVKR-EEIFYTIKLWATFFR---AELVHPALERSLKKLGP 111

Query: 548  DRLGIGQLHWSTANYAPLQERALWDG----------LVEMYDKGLVRAVGVSNYGP--KQ 691
            D + +  +H   A   P +E    D           L + ++  L+       Y P   Q
Sbjct: 112  DYVDLFIIHVPFAMKQPGKELLPKDASGEIILETVELCDTWELELILNKPGLRYKPTCNQ 171

Query: 692  LLKIHSYLASRGVPLSSAQVQFSLLSMGEEQMELKTVCDSLGVRLIAYSPLGLGMLTGKY 871
            +++ H YL                      Q +L   C S  + L+AYS LG      + 
Sbjct: 172  VVECHPYL---------------------NQSKLLEFCKSKDIVLVAYSALG-----SQR 205

Query: 872  DASNLPNGPRSVLFRQILPGLESLLS--CLKSIADRKGKTMSQVAINWCICKGAIPIPGV 1045
            D             + + P    LL    LKSIA +  ++  QVA+ + + +G + +   
Sbjct: 206  DP------------QWVDPDCPHLLEEPILKSIAKKHSRSPGQVALRYQLQRGVVVLAKS 253

Query: 1046 KTVRHVEDNLGALGWRLSPGEISELE 1123
             +   +++N     + L+P ++  ++
Sbjct: 254  FSQERIKENFQIFDFELTPEDMKAID 279
to top
>Q76KC2:PLD_MICLT Pyridoxal 4-dehydrogenase - Microbacterium luteolum (Aureobacterium|
           luteolum)
          Length = 342

 Score = 33.1 bits (74), Expect = 2.6
 Identities = 26/85 (30%), Positives = 37/85 (43%)
 Frame = +2

Query: 215 LSVSPMGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGTGKLNGQSE 394
           L+V+ +G GT   G      Y     ++          +GI  FD+A  YG G+     E
Sbjct: 16  LTVTALGLGTAPLGGL----YAPVSRADADALLEAGWDSGIRYFDSAPMYGYGR----CE 67

Query: 395 RLLGKFIRECQGPIKSPDDVVIATK 469
            LLG  +RE       P+  VI+TK
Sbjct: 68  HLLGDMLRE------KPERAVISTK 86
to top
>Q04212:ARA2_YEAST D-arabinose 1-dehydrogenase - Saccharomyces cerevisiae (Baker's|
           yeast)
          Length = 335

 Score = 33.1 bits (74), Expect = 2.6
 Identities = 50/204 (24%), Positives = 79/204 (38%), Gaps = 4/204 (1%)
 Frame = +2

Query: 194 EKVNVGPL-SVSPMGFGTWAWGNQLLWGYEESMDSELQECFNLALKNGINLFDTADSYGT 370
           EKVN   L SVSP+  G      Q     +E     L++    A  +GIN  DT+  Y  
Sbjct: 4   EKVNPFDLASVSPLVLGGAILNQQYT---DEPESIPLEDIIKYAFSHGINAIDTSPYY-- 58

Query: 371 GKLNGQSERLLGKFIRECQGPIKSPDDVVIATK---FAAYPWRLTSGQFVNACRSSLERL 541
               G SE L G+ +   +      D   I TK     A  +  +      +   S ERL
Sbjct: 59  ----GPSEVLYGRALSNLRNEFPR-DTYFICTKVGRIGAEEFNYSRDFVRFSVHRSCERL 113

Query: 542 QIDRLGIGQLHWSTANYAPLQERALWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSYLAS 721
               L +  LH       P    AL + L  + +KG+++  G+S Y    +  +  Y ++
Sbjct: 114 HTTYLDLVYLHDVEFVKFPDILEALKE-LRTLKNKGVIKNFGISGYPIDFITWLAEYCST 172

Query: 722 RGVPLSSAQVQFSLLSMGEEQMEL 793
               + S     S  ++  +  +L
Sbjct: 173 EESDIGSLDAVLSYCNLNLQNNKL 196
to top
>P39016:MPT5_YEAST Suppressor protein MPT5 - Saccharomyces cerevisiae (Baker's yeast)|
          Length = 859

 Score = 31.6 bits (70), Expect = 7.7
 Identities = 20/71 (28%), Positives = 36/71 (50%), Gaps = 1/71 (1%)
 Frame = +2

Query: 560 IGQLHWSTANYAPL-QERALWDGLVEMYDKGLVRAVGVSNYGPKQLLKIHSYLASRGVPL 736
           IGQ   ST NY     + +L  G + +  K L+ ++  ++Y  K  LK+ +Y  + G+P 
Sbjct: 544 IGQNSSSTLNYGNFCNDFSLKIGNLIVLTKELLPSIKTTSYAKKIKLKVKAYAEATGIPF 603

Query: 737 SSAQVQFSLLS 769
           +    Q + +S
Sbjct: 604 TDISPQVTAMS 614
to top
>P43561:FET5_YEAST Iron transport multicopper oxidase FET5 precursor - Saccharomyces|
           cerevisiae (Baker's yeast)
          Length = 622

 Score = 31.6 bits (70), Expect = 7.7
 Identities = 24/69 (34%), Positives = 32/69 (46%), Gaps = 6/69 (8%)
 Frame = -1

Query: 574 MQLPYSETVDL*PF**RPAGVDKLAGR*SPRIRGKLRCDDHVVWRFY----WPL--ALAD 413
           M +PY+E+  L PF  RP   D +    S  +  + R D+  VW F+    W L   LA 
Sbjct: 450 MTVPYNESAPLQPFPERPMVRDTVVLEPSGHVVLRFRADNPGVWYFHCHVDWHLQQGLAS 509

Query: 412 KFAEQPFAL 386
            F E P  L
Sbjct: 510 VFIEAPVLL 518
to top
>Q7N2T7:COBQ_PHOLL Cobyric acid synthase - Photorhabdus luminescens subsp. laumondii|
          Length = 512

 Score = 31.6 bits (70), Expect = 7.7
 Identities = 27/97 (27%), Positives = 41/97 (42%), Gaps = 11/97 (11%)
 Frame = +2

Query: 623 GLVEMYDKGLVRAVGVSN-------YGPKQLLKIHSYLASRGVPLSSAQVQFSLLSMGEE 781
           G+ EM D  ++    +         YG   LL+       +GV ++  +   SLL  G E
Sbjct: 151 GMAEMVDAPVLLVADIDRGGVFAAIYGTLALLRPAEKARVKGVIINKFRGDISLLQPGIE 210

Query: 782 QMELKTVCDSLGVR----LIAYSPLGLGMLTGKYDAS 880
           Q+E  T    LGV     +      G+ + TGKYD +
Sbjct: 211 QIEALTGVPVLGVMPWLDIDLEDEDGVALQTGKYDGA 247
to top
>Q8RAZ3:CHEB_THETN Chemotaxis response regulator protein-glutamate methylesterase -|
           Thermoanaerobacter tengcongensis
          Length = 367

 Score = 31.6 bits (70), Expect = 7.7
 Identities = 26/92 (28%), Positives = 42/92 (45%), Gaps = 5/92 (5%)
 Frame = +2

Query: 461 ATKFAAYPWRLTSGQFVNACRSSLERLQIDRLGIGQLHWSTANYAPLQERALWDGLVEMY 640
           A  F A P    S          + +++I  L   +L  S+ N+  L +R   +   ++Y
Sbjct: 102 AVDFVAKPGGTVSLGIKQLADEIVSKVRIAALSNKELLSSSRNFKKLLKRRNQEVTRKVY 161

Query: 641 D-----KGLVRAVGVSNYGPKQLLKIHSYLAS 721
           +     K +V  +GVS  GPK L++I  YL S
Sbjct: 162 ENKISKKEIVVVIGVSTGGPKTLMEILPYLPS 193


  Database: uniprot_sprot.fasta.out
    Posted date:  Jul 19, 2007  5:58 PM
  Number of letters in database: 100,686,439
  Number of sequences in database:  274,295
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 274295
Number of Hits to DB: 245,204,255
Number of extensions: 5637985
Number of successful extensions: 16989
Number of sequences better than 10.0: 140
Number of HSP's gapped: 16833
Number of HSP's successfully gapped: 142
Length of query: 436
Length of database: 100,686,439
Length adjustment: 116
Effective length of query: 320
Effective length of database: 68,868,219
Effective search space: 22037830080
Effective search space used: 22037830080
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
to top