ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | FLbaf108j06 |
|---|---|
| Clone Library Name | barley_pub |
>Q0VC13:ADAL_BOVIN Adenosine deaminase-like protein - Bos taurus (Bovine)| Length = 351 Score = 243 bits (621), Expect = 1e-63 Identities = 131/354 (37%), Positives = 211/354 (59%), Gaps = 10/354 (2%) Frame = +3 Query: 156 LPKVELHAHLNGSVRNSTLLELAKELGDKGVIVYEDVKDVIMKNDRSLPECFRLFDLFHI 335 LPKVELHAHLNGS+ ++T+ +L + D + +++ + + R+L EC ++F + H+ Sbjct: 17 LPKVELHAHLNGSISSNTIRKLIAKKPD--LKIHDQMTMIDKGEKRTLEECLQMFQIIHL 74 Query: 336 LTTDHDTVTRIAKEVIGDFAAENVVYLEIRTTPKNNEAKGMTKRSYMNAVVKGLKSVEDV 515 LTT + V + K+VI +FA + V YLE+R+TP+ +A GMTK++Y+ ++++G+K ++ Sbjct: 75 LTTTPEDVLMVTKDVIKEFADDGVKYLELRSTPRGEDATGMTKKTYVESILEGIKQSKEE 134 Query: 516 DVVLNDEKISCAPMSDFGGDTKRKKIYVRLLLSIDRRETTSAALDTVNLALEL---KDEG 686 +V ++ VR L+SIDRR +SAA + V LA E ++ Sbjct: 135 NVDID----------------------VRYLISIDRRGGSSAAKEAVKLAEEFFLSAEDT 172 Query: 687 VIGIDLSGNPVVGEWETYLPALERAKELGIPTTIHCGEVPNRK-EIQAMLDFCPQRLGHV 863 V+G+DLSG+P G+ + +L L AK+ G+ +H E+PN+K E Q +L+ P R+GH Sbjct: 173 VLGLDLSGDPSAGQAKDFLEPLLEAKKSGLKLALHLSEIPNQKTETQVLLNLFPDRIGHG 232 Query: 864 CCLDDEEWKK------LKSSMIPVEICLTSNVMTGGTPSLELHHFADLYNAKHPLSICTD 1025 L E ++ IP+E+CLTSNV + P+ + HHF Y+ HP ICTD Sbjct: 233 TFLSSSEEGSPDLVDFVRQHQIPLELCLTSNVKSQTVPAYDQHHFGFWYSVAHPAVICTD 292 Query: 1026 DSGLFSTSLSNEYYLVASTFGLSKAELFRLAQSAVEFVFADDEVKKSLRAAFEH 1187 D G+F+T LS EY LVA TF L++++++ L+ ++ ++FA D K LR + H Sbjct: 293 DKGVFATRLSQEYQLVAETFHLTQSQVWDLSYESISYIFASDSTKADLRKKWSH 346
>Q6DHV7:ADAL_HUMAN Adenosine deaminase-like protein - Homo sapiens (Human)| Length = 355 Score = 239 bits (610), Expect = 2e-62 Identities = 131/354 (37%), Positives = 207/354 (58%), Gaps = 10/354 (2%) Frame = +3 Query: 156 LPKVELHAHLNGSVRNSTLLELAKELGDKGVIVYEDVKDVIMKNDRSLPECFRLFDLFHI 335 LPKVELHAHLNGS+ + T+ +L + D + +++ + + R+L ECF++F H Sbjct: 18 LPKVELHAHLNGSISSHTMKKLIAQKPD--LKIHDQMTVIDKGKKRTLEECFQMFQTIHQ 75 Query: 336 LTTDHDTVTRIAKEVIGDFAAENVVYLEIRTTPKNNEAKGMTKRSYMNAVVKGLKSVEDV 515 LT+ + + + K+VI +FA + V YLE+R+TP+ A GMTK++Y+ ++++G+K + Sbjct: 76 LTSSPEDILMVTKDVIKEFADDGVKYLELRSTPRRENATGMTKKTYVESILEGIKQSKQE 135 Query: 516 DVVLNDEKISCAPMSDFGGDTKRKKIYVRLLLSIDRRETTSAALDTVNLALE--LKDEG- 686 ++ ++ VR L+++DRR A +TV LA E L EG Sbjct: 136 NLDID----------------------VRYLIAVDRRGGPLVAKETVKLAEEFFLSTEGT 173 Query: 687 VIGIDLSGNPVVGEWETYLPALERAKELGIPTTIHCGEVPN-RKEIQAMLDFCPQRLGHV 863 V+G+DLSG+P VG+ + +L L AK+ G+ +H E+PN +KE Q +LD P R+GH Sbjct: 174 VLGLDLSGDPTVGQAKDFLEPLLEAKKAGLKLALHLSEIPNQKKETQILLDLLPDRIGHG 233 Query: 864 CCLDDEEWKKL------KSSMIPVEICLTSNVMTGGTPSLELHHFADLYNAKHPLSICTD 1025 L+ E L + IP+E+CLTSNV + PS + HHF Y+ HP ICTD Sbjct: 234 TFLNSGEGGSLDLVDFVRQHRIPLELCLTSNVKSQTVPSYDQHHFGFWYSIAHPSVICTD 293 Query: 1026 DSGLFSTSLSNEYYLVASTFGLSKAELFRLAQSAVEFVFADDEVKKSLRAAFEH 1187 D G+F+T LS EY L A TF L++++++ L+ ++ ++FA D + LR + H Sbjct: 294 DKGVFATHLSQEYQLAAETFNLTQSQVWDLSYESINYIFASDSTRSELRKKWNH 347
>Q80SY6:ADAL_MOUSE Adenosine deaminase-like protein - Mus musculus (Mouse)| Length = 360 Score = 232 bits (591), Expect = 3e-60 Identities = 131/354 (37%), Positives = 201/354 (56%), Gaps = 10/354 (2%) Frame = +3 Query: 156 LPKVELHAHLNGSVRNSTLLELAKELGDKGVIVYEDVKDVIMKNDRSLPECFRLFDLFHI 335 LPKVELHAHLNGS+ +ST+ +L + V + + D K R+L ECF++F + H Sbjct: 17 LPKVELHAHLNGSISSSTMKKLIAKKPHLNVHGHMTMIDKGKK--RTLQECFQMFQVIHQ 74 Query: 336 LTTDHDTVTRIAKEVIGDFAAENVVYLEIRTTPKNNEAKGMTKRSYMNAVVKGLKSVEDV 515 LTT + + + K+VI +FA + V YLE+R+TP+ A GMT+++Y+ +V++G+K + Sbjct: 75 LTTSAEDILMVTKDVIKEFADDGVKYLELRSTPREENATGMTRKTYVESVLEGIKQCKQE 134 Query: 516 DVVLNDEKISCAPMSDFGGDTKRKKIYVRLLLSIDRRETTSAALDTVNLALEL---KDEG 686 ++ ++ VR L++IDRR + A +TV LA E + Sbjct: 135 NLDID----------------------VRYLMAIDRRGGPTIARETVELAKEFFLSTENT 172 Query: 687 VIGIDLSGNPVVGEWETYLPALERAKELGIPTTIHCGEVPNR-KEIQAMLDFCPQRLGHV 863 V+G+DLSG+P +G+ +L L AK+ G+ +H E+PNR KE Q +L P R+GH Sbjct: 173 VLGLDLSGDPTIGQANDFLEPLLEAKKAGLKLALHLAEIPNREKENQMLLSLLPDRIGHG 232 Query: 864 CCLDDEEWKKL------KSSMIPVEICLTSNVMTGGTPSLELHHFADLYNAKHPLSICTD 1025 L E L + IP+E+CLTSN+ + PS + HHF Y+ HP ICTD Sbjct: 233 TFLSASEAGALDQVDFVRQHQIPLELCLTSNIKSQTVPSYDQHHFGFWYSIAHPSVICTD 292 Query: 1026 DSGLFSTSLSNEYYLVASTFGLSKAELFRLAQSAVEFVFADDEVKKSLRAAFEH 1187 D G+F+T LS EY L A TF L+ +++ L+ ++ ++FA D + LR + H Sbjct: 293 DKGVFATYLSQEYQLAAETFNLTPFQVWDLSYESINYIFACDNTRSELRKRWTH 346
>Q4V9P6:ADAL_DANRE Adenosine deaminase-like protein - Danio rerio (Zebrafish)| (Brachydanio rerio) Length = 348 Score = 221 bits (564), Expect = 4e-57 Identities = 132/349 (37%), Positives = 192/349 (55%), Gaps = 11/349 (3%) Frame = +3 Query: 156 LPKVELHAHLNGSVRNSTLLELAKELGDKGVIVYEDVKDVIMKNDR-SLPECFRLFDLFH 332 LPKVELHAHLNGSV T+ +L K K + E I + R +L ECF++F + H Sbjct: 12 LPKVELHAHLNGSVSFETMEKLIKR---KPHLNIEHSMTAIRRGQRRTLDECFQVFKVIH 68 Query: 333 ILTTDHDTVTRIAKEVIGDFAAENVVYLEIRTTPKNNEAKGMTKRSYMNAVVKGLKSVED 512 L + + +AK VI +FAA+ V YLE+R+TP+ G++K+ Y+ V++ ++ + Sbjct: 69 QLVDSEEDILMVAKSVIQEFAADGVKYLELRSTPREVTETGLSKQRYIETVLEAIRQCKQ 128 Query: 513 VDVVLNDEKISCAPMSDFGGDTKRKKIYVRLLLSIDRRETTSAALDTVNLALEL---KDE 683 V ++ VR L+++DRR A+ TV LA + D Sbjct: 129 EGVDID----------------------VRFLVAVDRRHGPEVAMQTVKLAEDFLLSSDG 166 Query: 684 GVIGIDLSGNPVVGEWETYLPALERAKELGIPTTIHCGEVPNR-KEIQAMLDFCPQRLGH 860 V+G+DLSG+P VG + L AL++AK G+ +H EVP++ E + +L+ P R+GH Sbjct: 167 TVVGLDLSGDPTVGHGKDLLAALQKAKNCGLKLALHLSEVPSQIDETELLLNLPPDRIGH 226 Query: 861 VCCL------DDEEWKKLKSSMIPVEICLTSNVMTGGTPSLELHHFADLYNAKHPLSICT 1022 L D K+ IP+EICLTSNV PS + HHF YN HP +CT Sbjct: 227 GTFLHPDVGGSDSLVDKVCKQNIPIEICLTSNVKGQTVPSYDKHHFKYWYNRGHPCVLCT 286 Query: 1023 DDSGLFSTSLSNEYYLVASTFGLSKAELFRLAQSAVEFVFADDEVKKSL 1169 DD G+F T LS EY L ASTFGL+K ++ L+Q A+ + FA + +K+ L Sbjct: 287 DDKGVFCTDLSQEYQLAASTFGLTKEAVWILSQQAIGYTFAPEPIKQRL 335
>Q295P6:ADAL_DROPS Adenosine deaminase-like protein - Drosophila pseudoobscura (Fruit| fly) Length = 337 Score = 212 bits (539), Expect = 3e-54 Identities = 128/349 (36%), Positives = 190/349 (54%), Gaps = 5/349 (1%) Frame = +3 Query: 156 LPKVELHAHLNGSVRNSTLLELAKELGDKGVIVYEDV--KDVIMKNDRSLPECFRLFDLF 329 +PKVELHAHLNGS+ ++L +LA+++ + + + V + D +L +CF F Sbjct: 8 MPKVELHAHLNGSLNTNSLQDLAEKVYGNTSEEFSHLCARFVNFEKDSNLDKCFEKFAFV 67 Query: 330 HILTTDHDTVTRIAKEVIGDFAAENVVYLEIRTTPKNNEAKGMTKRSYMNAVVKGLKSVE 509 H LT+ + + VI DFA +N+ YLE+RTTPK N K +R Y+ V+ Sbjct: 68 HELTSTAAGLQYATELVIRDFANDNIQYLELRTTPKAN--KNYLRRDYLRIVL------- 118 Query: 510 DVDVVLNDEKISCAPMSDFGGDTKRKKIYVRLLLSIDRRETTSAALDTVNLALELKDEG- 686 D + K K I V+LL SI+R E + A +TV LALE Sbjct: 119 --DTIKRSRK-------------KYPNILVKLLPSINRSEPVAVAEETVALALEFAKTDP 163 Query: 687 --VIGIDLSGNPVVGEWETYLPALERAKELGIPTTIHCGEVPNRKEIQAMLDFCPQRLGH 860 V+GIDLSG P G++ + AL+ A+ G+ IHC E+ N EI+ ML F R GH Sbjct: 164 DLVVGIDLSGIPTKGKFTDFCGALDLARREGLKLVIHCAEIDNPPEIKEMLSFGMSRCGH 223 Query: 861 VCCLDDEEWKKLKSSMIPVEICLTSNVMTGGTPSLELHHFADLYNAKHPLSICTDDSGLF 1040 L +E++ ++K++ IP+E CLTSN+ +G S E HH L + P +CTDDSG+F Sbjct: 224 GTYLTEEDFAQMKAANIPIECCLTSNIKSGSVSSFEEHHLKRLMESDAPRVVCTDDSGVF 283 Query: 1041 STSLSNEYYLVASTFGLSKAELFRLAQSAVEFVFADDEVKKSLRAAFEH 1187 TSL+NE+ LV TF +++ + L AV+ FA ++ ++ + EH Sbjct: 284 DTSLTNEFLLVVETFNVTRDQCIDLTLEAVKHSFASEQERQQMALKVEH 332
>Q4V831:ADALA_XENLA Adenosine deaminase-like protein A - Xenopus laevis (African clawed| frog) Length = 347 Score = 212 bits (539), Expect = 3e-54 Identities = 123/346 (35%), Positives = 199/346 (57%), Gaps = 7/346 (2%) Frame = +3 Query: 156 LPKVELHAHLNGSVRNSTLLELAKELGDKGVIVYEDVKDVIMKND-RSLPECFRLFDLFH 332 LPKVELHAHLNGS+ +T+ +L + K + + +I K R+L ECF++F + H Sbjct: 13 LPKVELHAHLNGSISTATMKKL---MARKPHLDIQHGMTMIDKGQKRTLEECFQMFKIIH 69 Query: 333 ILTTDHDTVTRIAKEVIGDFAAENVVYLEIRTTPKNNEAKGMTKRSYMNAVVKGLKSVED 512 +T + + + K+VI +FAA+ V YLE+R+TP++ A G+TK++Y+ V++G+K ++ Sbjct: 70 QITDTAEDILLVTKDVIKEFAADGVKYLELRSTPRDTPA-GLTKQAYVETVLEGIKQCKE 128 Query: 513 VDVVLNDEKISCAPMSDFGGDTKRKKIYVRLLLSIDRRETTSAALDTVNLALEL---KDE 683 V ++ VR LL+IDRR +AA +TV LA + +E Sbjct: 129 EGVDID----------------------VRFLLAIDRRGGPTAAKETVKLAEDFFCSSNE 166 Query: 684 GVIGIDLSGNPVVGEWETYLPALERAKELGIPTTIHCGEVPNR-KEIQAMLDFCPQRLGH 860 V+G+DLSG+P VG ++ L +A++ G+ +H E+P++ +E + +L P R+GH Sbjct: 167 LVLGLDLSGDPTVGHGRDFMEPLNKARQSGLKLALHLSEIPSQTEETELLLGLPPDRIGH 226 Query: 861 VCCLDDEEW--KKLKSSMIPVEICLTSNVMTGGTPSLELHHFADLYNAKHPLSICTDDSG 1034 L + +K IP+E+C+TSN+ S HHF YN HP +CTDD G Sbjct: 227 GTFLTTSAHIVEIVKKQHIPLELCITSNIKGQTVSSYNEHHFGFWYNLHHPFVLCTDDKG 286 Query: 1035 LFSTSLSNEYYLVASTFGLSKAELFRLAQSAVEFVFADDEVKKSLR 1172 +F+T LS EY + A TF L+ ++ L+ A+++ FA +VK +L+ Sbjct: 287 VFATDLSVEYEIAAKTFNLTPHHVWDLSYQAIDYTFASADVKANLK 332
>Q9VHH7:ADAL_DROME Adenosine deaminase-like protein - Drosophila melanogaster (Fruit| fly) Length = 337 Score = 208 bits (529), Expect = 5e-53 Identities = 124/343 (36%), Positives = 181/343 (52%), Gaps = 3/343 (0%) Frame = +3 Query: 135 MRAWCVALPKVELHAHLNGSVRNSTLLELAKELGDKGVIVYEDVKDVIMKNDRSLPECFR 314 M + LPKVELHAHLNGS+ +L +L + L + + + ++ + CF Sbjct: 1 MEQFLKGLPKVELHAHLNGSLGIKSLCDLGERLYGTSCKDFLKLCAHFSRFEKDMDACFE 60 Query: 315 LFDLFHILTTDHDTVTRIAKEVIGDFAAENVVYLEIRTTPKNNEAKGMTKRSYMNAVVKG 494 F H LT+ + + + I DFA +NV Y+E+RTTPK NE ++R Y+ V+ Sbjct: 61 KFAFVHELTSTREGLRFATELAIRDFAEDNVQYVEMRTTPKANE--NYSRRDYLQIVIDA 118 Query: 495 LKSVEDVDVVLNDEKISCAPMSDFGGDTKRKKIYVRLLLSIDRRETTSAALDTVNLALEL 674 +K+ + +I V+LL SI+R E A +TV+LA+EL Sbjct: 119 IKAASET----------------------YPEITVKLLPSINRAEPVDVAEETVSLAVEL 156 Query: 675 KDEG---VIGIDLSGNPVVGEWETYLPALERAKELGIPTTIHCGEVPNRKEIQAMLDFCP 845 ++GIDLSGNP G + + P L +A++ G+ IHC E+ N E++ ML F Sbjct: 157 ARAHPNLILGIDLSGNPGKGRFSDFAPILAQARDKGLKLAIHCAEIENPSEVKEMLHFGM 216 Query: 846 QRLGHVCCLDDEEWKKLKSSMIPVEICLTSNVMTGGTPSLELHHFADLYNAKHPLSICTD 1025 R GH L E+ +LK I +E CLTSNV +G PSLE HH + A P ICTD Sbjct: 217 SRCGHGTFLTPEDIGQLKQRNIAIECCLTSNVKSGTVPSLEEHHLKRIMEADAPKVICTD 276 Query: 1026 DSGLFSTSLSNEYYLVASTFGLSKAELFRLAQSAVEFVFADDE 1154 DSG+F T+L+ E+ + A TFGL++ + L AV FA ++ Sbjct: 277 DSGVFDTTLTKEFLIAAETFGLTREQCIDLTLEAVHHSFASEQ 319
>Q8XHH8:ADD_CLOPE Adenosine deaminase - Clostridium perfringens| Length = 332 Score = 139 bits (351), Expect = 2e-32 Identities = 99/345 (28%), Positives = 172/345 (49%), Gaps = 6/345 (1%) Frame = +3 Query: 156 LPKVELHAHLNGSVRNSTLLELAKELGDK-GVIVYEDVKD--VIMKNDRSLPECFRLFDL 326 LPK+ELH HL+GS+R T +ELAK+ G K Y+ VK+ VI K SL + F L Sbjct: 6 LPKIELHCHLDGSLRVETAIELAKKEGVKLDSYEYDKVKELLVIPKECNSLEDYLNRFAL 65 Query: 327 FHILTTDHDTVTRIAKEVIGDFAAENVVYLEIRTTPKNNEAKGMTKRSYMNAVVKGLKSV 506 L + + R+A E++ D + ENV Y+EIR P + KGMT++ + +V+KG++ Sbjct: 66 PVKLLQRAENLERVAFELMEDASKENVKYIEIRFAPLLHLEKGMTQKEVIESVIKGIRKA 125 Query: 507 EDVDVVLNDEKISCAPMSDFGGDTKRKKIYVRLLLSIDRRETTSAALDTVNLALELKDEG 686 E+ + D G+ L+LS R + + + + +G Sbjct: 126 EE--------------LYDIKGN---------LILSCLRHHSIDSVYEVIEEGKNFIGKG 162 Query: 687 VIGIDLSGNPVVGEWETYLPALERAKELGIPTTIHCGEVPNRKEIQAMLDFC-PQRLGHV 863 V+ IDL+G + G + Y ++ A+E G TIH GE K ++ ++ +R+GH Sbjct: 163 VVAIDLAGGELEGFVKPYEEVMKLARESGFRVTIHAGETGYGKNVRDAIELLGAERIGHG 222 Query: 864 CCL--DDEEWKKLKSSMIPVEICLTSNVMTGGTPSLELHHFADLYNAKHPLSICTDDSGL 1037 + D+E + +K + +E+C SN+ T G E H + +++ TD+ + Sbjct: 223 LFIFNDEEAYNLVKEKGVTLEMCPKSNIDTKGVNKYEDHPIYKYHKDNIRVNLSTDNRTV 282 Query: 1038 FSTSLSNEYYLVASTFGLSKAELFRLAQSAVEFVFADDEVKKSLR 1172 + +L+ E+ V TF + + ++ ++VE F +E+K+ L+ Sbjct: 283 SNINLTEEFENVHKTFNIDFEDYKKIYLNSVEASFCSEELKEKLK 327
>Q8D6Q8:ADD_VIBVU Adenosine deaminase - Vibrio vulnificus| Length = 331 Score = 131 bits (330), Expect = 6e-30 Identities = 97/345 (28%), Positives = 168/345 (48%), Gaps = 7/345 (2%) Frame = +3 Query: 156 LPKVELHAHLNGSVRNSTLLELAKE----LGDKGVIVYEDVKDVIMKNDRSLPECFRLFD 323 LPK++LH HL+GSVR T+++LA E L + + V +++ V + +L E + F+ Sbjct: 6 LPKIDLHCHLDGSVRPQTIIDLADEQNLTLPSRDINVIKEMM-VAPETCPNLDEYLKRFE 64 Query: 324 LFHILTTDHDTVTRIAKEVIGDFAAENVVYLEIRTTPKNNEAKGMTKRSYMNAVVKGLKS 503 L ++ + + RI+ E+ D A ENV YLE+R P ++ KG++ M++VV+G+K Sbjct: 65 LPGMVMQTAEALERISFELFEDAANENVKYLEVRFGPLLHQVKGLSLDDIMDSVVRGMKR 124 Query: 504 VEDVDVVLNDEKISCAPMSDFGGDTKRKKIYVRLLLSIDRRETTSAALDTVNLALELKDE 683 E + I+ +LSI R + + ++ Sbjct: 125 AE-----------------------AQYDIHGNYILSILRTMPKDQIKAVLEAGAKHLND 161 Query: 684 GVIGIDLSGNPVVGEWETYLPALERAKELGIPTTIHCGEVPNRKEIQAMLDFC-PQRLGH 860 G++ DL+G+ V G ++P + AKELG TIH GE + + + +R+GH Sbjct: 162 GIVAFDLAGSEVPGFCHEFVPYAQYAKELGYRITIHAGEQGAGQNVYDAISLLGAERVGH 221 Query: 861 VCCLDD--EEWKKLKSSMIPVEICLTSNVMTGGTPSLELHHFADLYNAKHPLSICTDDSG 1034 + + E ++ +K + +E C +SNV T SL H Y ++I TD+ Sbjct: 222 GIFIHNHPEAYQLVKGEEVALETCPSSNVQTKAVNSLSEHPIKAFYKDGIAVTINTDNRT 281 Query: 1035 LFSTSLSNEYYLVASTFGLSKAELFRLAQSAVEFVFADDEVKKSL 1169 + +T++++E V F L++AE F + +V F D VK+ L Sbjct: 282 VSNTTMTDEVRKVVEAFELTEAEYFDIYTISVNNAFTSDAVKQHL 326
>Q7MDL6:ADD_VIBVY Adenosine deaminase - Vibrio vulnificus (strain YJ016)| Length = 331 Score = 131 bits (329), Expect = 8e-30 Identities = 96/345 (27%), Positives = 168/345 (48%), Gaps = 7/345 (2%) Frame = +3 Query: 156 LPKVELHAHLNGSVRNSTLLELAKE----LGDKGVIVYEDVKDVIMKNDRSLPECFRLFD 323 LPK++LH HL+GSVR T+++LA E L + + V +++ V + +L E + F+ Sbjct: 6 LPKIDLHCHLDGSVRPQTIIDLADEQNLTLPSRDINVIKEMM-VAPETCPNLDEYLKRFE 64 Query: 324 LFHILTTDHDTVTRIAKEVIGDFAAENVVYLEIRTTPKNNEAKGMTKRSYMNAVVKGLKS 503 L ++ + + RI+ E+ D A ENV YLE+R P ++ KG++ M++VV+G+K Sbjct: 65 LPGMVMQTAEALERISFELFEDAANENVKYLEVRFGPLLHQVKGLSLDDIMDSVVRGMKR 124 Query: 504 VEDVDVVLNDEKISCAPMSDFGGDTKRKKIYVRLLLSIDRRETTSAALDTVNLALELKDE 683 E + I+ +LSI R + + ++ Sbjct: 125 AE-----------------------AQYDIHGNYILSILRTMPKDQIKAVLEAGAKHLND 161 Query: 684 GVIGIDLSGNPVVGEWETYLPALERAKELGIPTTIHCGEVPNRKEIQAMLDFC-PQRLGH 860 G++ DL+G+ + G ++P + AKELG TIH GE + + + +R+GH Sbjct: 162 GIVAFDLAGSEIPGFCHEFVPYAQYAKELGYRITIHAGEQGAGQNVYDAISLLGAERVGH 221 Query: 861 VCCLDD--EEWKKLKSSMIPVEICLTSNVMTGGTPSLELHHFADLYNAKHPLSICTDDSG 1034 + + E ++ +K + +E C +SNV T SL H Y ++I TD+ Sbjct: 222 GIFIHNHPEAYQLVKGEEVALETCPSSNVQTKAVNSLSEHPIKAFYKDGIAVTINTDNRT 281 Query: 1035 LFSTSLSNEYYLVASTFGLSKAELFRLAQSAVEFVFADDEVKKSL 1169 + +T++++E V F L++AE F + +V F D VK+ L Sbjct: 282 VSNTTMTDEVRKVVEAFELTEAEYFDIYTISVNNAFTSDAVKQHL 326
>Q839J4:ADD_ENTFA Adenosine deaminase - Enterococcus faecalis (Streptococcus faecalis)| Length = 337 Score = 130 bits (327), Expect = 1e-29 Identities = 99/349 (28%), Positives = 161/349 (46%), Gaps = 4/349 (1%) Frame = +3 Query: 156 LPKVELHAHLNGSVRNSTLLELAKELGDKGVIVYEDVKDVIMKNDR--SLPECFRLFDLF 329 LPK+ELH HL+GS+R +TL +A++ + +K++++ ++ L + FD Sbjct: 9 LPKIELHCHLDGSIRPTTLRTIAEKQNIPLPQDEQALKELVVAPEKCTDLNDYLTRFDFV 68 Query: 330 HILTTDHDTVTRIAKEVIGDFAAENVVYLEIRTTPKNNEAKGMTKRSYMNAVVKGLKSVE 509 + + A +VI A + V Y+E+R P + KG+ + AV+ GLK E Sbjct: 69 LTCLQTAEALQAAAYDVISQAAEDGVAYIEVRFAPSQHTEKGLRLPEIVTAVLTGLKQGE 128 Query: 510 DVDVVLNDEKISCAPMSDFGGDTKRKKIYVRLLLSIDRRETTSAALDTVNLALELKDEGV 689 + DFG + LL R + A V+LA + ++ GV Sbjct: 129 E----------------DFG-------VKSNALLCGMRHDQQQAIEKIVHLAHDFRETGV 165 Query: 690 IGIDLSGNPVVGEWETYLPALERAKELGIPTTIHCGEVPNRKEIQAMLDFCPQRLGHVCC 869 +G DL+GN V T+ L A +L IP T+H GE K + + R+GH Sbjct: 166 VGFDLAGNEVDFPPYTFEDVLALANQLSIPLTLHAGECGCGKNVADAVTLGATRIGHGIA 225 Query: 870 LDD--EEWKKLKSSMIPVEICLTSNVMTGGTPSLELHHFADLYNAKHPLSICTDDSGLFS 1043 L D E LK + +E+C TSN TG +L + F A + I TD+ + Sbjct: 226 LKDTPEYLALLKEKKVLLEMCPTSNFQTGTVKTLAEYPFQQFIEAGLAVCINTDNRTVSD 285 Query: 1044 TSLSNEYYLVASTFGLSKAELFRLAQSAVEFVFADDEVKKSLRAAFEHA 1190 T+L+ E+ +A+ + LS E+ +L ++A+ F + KK L + A Sbjct: 286 TTLTKEFMKLATWYQLSYDEMKQLTKNALAGAFLSPDEKKLLNQKIDQA 334
>Q8IG39:ADAL_CAEEL Adenosine deaminase-like protein - Caenorhabditis elegans| Length = 388 Score = 121 bits (304), Expect = 6e-27 Identities = 95/336 (28%), Positives = 158/336 (47%), Gaps = 6/336 (1%) Frame = +3 Query: 156 LPKVELHAHLNGSVRNSTLLELAKELGDKGVIVYEDVKDVIMKNDRSLPECFRLFDLFHI 335 +PKVELHAHL+GS+ T+ +L E + E +K ++ ++ F F + H Sbjct: 59 MPKVELHAHLSGSLSPETI-KLIMESDETRA--EEIMKKYKLEKPENMTGVFDCFPVIHA 115 Query: 336 LTTDHDTVTRIAKEVIGDFAAENVVYLEIRTTPKNNEAKGMTKRSYMNAVVKGLKSVEDV 515 + + + ++ I +F +N VYLE+RT+PK E MT Y+ ++ ++ + Sbjct: 116 ILRKPEAIRIAIRQTIKEFEEDNCVYLELRTSPK--ETDFMTYEDYLQVCIESFEAAKH- 172 Query: 516 DVVLNDEKISCAPMSDFGGDTKRKKIYVRLLLSIDRRETTSAALDTVNLALELKDEG--V 689 + +I L++S+DRR A + L E + + Sbjct: 173 ---------------------EFPRIKTFLIVSLDRRMPFETAAHILGLIGEAQQRTNVI 211 Query: 690 IGIDLSGNPVVGEWETYLPALERAKELGIPTTIHCGEV-PNRKEIQAMLDFCPQRLGHVC 866 +G++LSG+P + + + G+ TIH EV N +++ L+ P R+GH Sbjct: 212 VGVELSGDPHLDGRRLLKLFVAARRFHGLGITIHLAEVLQNMADVEDYLNLRPDRIGHGT 271 Query: 867 CLDDEEWKKLKSSM--IPVEICLTSNVMTGGTPSLELHHFADLYNAKHPLSICTDDSGLF 1040 L + + + ++ IP+EICL+SNV + T + HF P+ ICTDD G+ Sbjct: 272 FLHTDPYTEYLTNKYKIPLEICLSSNVYSKTTTNYRNSHFNYWRKRGVPVFICTDDKGVI 331 Query: 1041 -STSLSNEYYLVASTFGLSKAELFRLAQSAVEFVFA 1145 +L+ EYY A TF LS EL + Q A+ FA Sbjct: 332 PGATLTEEYYKAAITFDLSTEELIGINQDALLNSFA 367
>P63910:ADD_STRA5 Adenosine deaminase - Streptococcus agalactiae serotype V| Length = 340 Score = 120 bits (300), Expect = 2e-26 Identities = 91/345 (26%), Positives = 155/345 (44%), Gaps = 7/345 (2%) Frame = +3 Query: 156 LPKVELHAHLNGSVRNSTLLELAKELGDKGVIVYEDVKD-----VIMKNDRSLPECFRLF 320 L K ELH HL+GS+ + +LA + D +I+ K+ + SL + + F Sbjct: 9 LAKAELHCHLDGSLSLPAIRKLAN-MAD--IILPSSDKELRKYVIAPAQTESLVDYLKTF 65 Query: 321 DLFHILTTDHDTVTRIAKEVIGDFAAENVVYLEIRTTPKNNEAKGMTKRSYMNAVVKGLK 500 + L + + A +V A ENV+Y+EIR P+ + KG+T + AV++GL Sbjct: 66 EFIRPLLQTKEALRFAAYDVARQAALENVIYIEIRFAPELSMDKGLTASDTVLAVLEGLA 125 Query: 501 SVEDVDVVLNDEKISCAPMSDFGGDTKRKKIYVRLLLSIDRRETTSAALDTVNLALELKD 680 + K I R L+ R+ + D + ++L Sbjct: 126 DAQ-----------------------KEFNIVARALVCGMRQSSHKTTKDIIKHIVDLAP 162 Query: 681 EGVIGIDLSGNPVVGEWETYLPALERAKELGIPTTIHCGEVPNRKEIQAMLDFCPQRLGH 860 +G++G D +G+ ++ + ++ K G P T+H GE K I L+ +R+GH Sbjct: 163 KGLVGFDFAGDEFSYPTDSLVDLIQEVKRSGYPMTLHAGECGCAKHIADSLNLGIKRMGH 222 Query: 861 VCCLDDEE--WKKLKSSMIPVEICLTSNVMTGGTPSLELHHFADLYNAKHPLSICTDDSG 1034 V L + K+ E+CLTSN+ T S++ + +LY+A ++I TD+ Sbjct: 223 VTALTGQRDLIKRFVEEDAVAEMCLTSNLQTKAASSIQSFPYQELYDAGGKITINTDNRT 282 Query: 1035 LFSTSLSNEYYLVASTFGLSKAELFRLAQSAVEFVFADDEVKKSL 1169 + T+L+ EY L + FG + Q+AV+ F D K +L Sbjct: 283 VSDTNLTKEYSLFVTYFGTKIEDFLVFNQNAVKASFTSDSEKDTL 327
>P63909:ADD_STRA3 Adenosine deaminase - Streptococcus agalactiae serotype III| Length = 340 Score = 120 bits (300), Expect = 2e-26 Identities = 91/345 (26%), Positives = 155/345 (44%), Gaps = 7/345 (2%) Frame = +3 Query: 156 LPKVELHAHLNGSVRNSTLLELAKELGDKGVIVYEDVKD-----VIMKNDRSLPECFRLF 320 L K ELH HL+GS+ + +LA + D +I+ K+ + SL + + F Sbjct: 9 LAKAELHCHLDGSLSLPAIRKLAN-MAD--IILPSSDKELRKYVIAPAQTESLVDYLKTF 65 Query: 321 DLFHILTTDHDTVTRIAKEVIGDFAAENVVYLEIRTTPKNNEAKGMTKRSYMNAVVKGLK 500 + L + + A +V A ENV+Y+EIR P+ + KG+T + AV++GL Sbjct: 66 EFIRPLLQTKEALRFAAYDVARQAALENVIYIEIRFAPELSMDKGLTASDTVLAVLEGLA 125 Query: 501 SVEDVDVVLNDEKISCAPMSDFGGDTKRKKIYVRLLLSIDRRETTSAALDTVNLALELKD 680 + K I R L+ R+ + D + ++L Sbjct: 126 DAQ-----------------------KEFNIVARALVCGMRQSSHKTTKDIIKHIVDLAP 162 Query: 681 EGVIGIDLSGNPVVGEWETYLPALERAKELGIPTTIHCGEVPNRKEIQAMLDFCPQRLGH 860 +G++G D +G+ ++ + ++ K G P T+H GE K I L+ +R+GH Sbjct: 163 KGLVGFDFAGDEFSYPTDSLVDLIQEVKRSGYPMTLHAGECGCAKHIADSLNLGIKRMGH 222 Query: 861 VCCLDDEE--WKKLKSSMIPVEICLTSNVMTGGTPSLELHHFADLYNAKHPLSICTDDSG 1034 V L + K+ E+CLTSN+ T S++ + +LY+A ++I TD+ Sbjct: 223 VTALTGQRDLIKRFVEEDAVAEMCLTSNLQTKAASSIQSFPYQELYDAGGKITINTDNRT 282 Query: 1035 LFSTSLSNEYYLVASTFGLSKAELFRLAQSAVEFVFADDEVKKSL 1169 + T+L+ EY L + FG + Q+AV+ F D K +L Sbjct: 283 VSDTNLTKEYSLFVTYFGTKIEDFLVFNQNAVKASFTSDSEKDTL 327
>O86737:ADD1_STRCO Probable adenosine deaminase 1 - Streptomyces coelicolor| Length = 387 Score = 116 bits (291), Expect = 2e-25 Identities = 98/377 (25%), Positives = 159/377 (42%), Gaps = 14/377 (3%) Frame = +3 Query: 60 RAPGRRRSKTKPAAMGTQTSEAEKEMRAWCVALPKVELHAHLNGSVRNSTLLELAKELGD 239 RA RR +P + +++ A+ LPK ELH H GS + ELA D Sbjct: 23 RAARGRRLGEEPLTEHLVDPDVPRDLHAFIAGLPKAELHVHHVGSASPRIVSELAARHAD 82 Query: 240 KGVIVYEDVKDVIMKNDRSLPECFRLFDLFHI---------LTTDHDTVTRIAKEVIGDF 392 V + +L + F D H L + V + EV D Sbjct: 83 SKVPT----------DPEALVDYFTFTDFAHFIDVYLSVVDLIRTPEDVRLLTYEVARDM 132 Query: 393 AAENVVYLEIRTTPKNNEAKGMTKRSYMNAVVKGLKSVEDVDVVLNDEKISCAPMSDFGG 572 A + V Y E+ TP ++ +G+ + ++M+A+ K+ E ++FG Sbjct: 133 ARQQVRYAELTITPFSSTRRGIDEGAFMDAIEDARKAAE----------------AEFG- 175 Query: 573 DTKRKKIYVRLLLSIDRRETTSAALDTVNLALE--LKDEGVIGIDLSGNPVVGEWETYLP 746 +R I +A +T LA + L+ EG++ L G + + P Sbjct: 176 ------TVLRWCFDIPGEAGLESAEETARLATDDRLRPEGLVSFGLGGPEIGVARPQFKP 229 Query: 747 ALERAKELGIPTTIHCGEVPNRKEI-QAMLDFCPQRLGH--VCCLDDEEWKKLKSSMIPV 917 +RA G+ + H GE + + +A++D +R+GH D + L IP+ Sbjct: 230 YFDRAIAAGLHSVPHAGETTGPQTVWEALIDLRAERIGHGTSSAQDPKLLAHLAERRIPL 289 Query: 918 EICLTSNVMTGGTPSLELHHFADLYNAKHPLSICTDDSGLFSTSLSNEYYLVASTFGLSK 1097 E+C TSN+ T +L+ H + A P++I +DD +F T L+NEY + A GL + Sbjct: 290 EVCPTSNIATRAVRTLDEHPIKEFVRAGVPVTINSDDPPMFGTDLNNEYAVAARLLGLDE 349 Query: 1098 AELFRLAQSAVEFVFAD 1148 L LA++ VE F D Sbjct: 350 RGLADLAKNGVEASFLD 366
>Q8DTN8:ADD_STRMU Adenosine deaminase - Streptococcus mutans| Length = 349 Score = 112 bits (281), Expect = 3e-24 Identities = 93/352 (26%), Positives = 153/352 (43%), Gaps = 7/352 (1%) Frame = +3 Query: 156 LPKVELHAHLNGSVRNSTLLELAKELGDKGVIVYEDVKDV-----IMKNDRSLPECFRLF 320 L K ELH HL+GS+ T+ ELA+ + + E ++ + ++ +L + + F Sbjct: 19 LVKTELHCHLDGSLSFETIRELAEMAN---IALPESDSELAKLVTVPEDSETLLDYLKTF 75 Query: 321 DLFHILTTDHDTVTRIAKEVIGDFAAENVVYLEIRTTPKNNEAKGMTKRSYMNAVVKGLK 500 D L ++ A +V AAE+V+Y+EIR P+ + KG++ + AV KGL+ Sbjct: 76 DFIRPLLQTQKALSLAAYDVAKQAAAEHVLYIEIRFAPELSMDKGLSAVQVVEAVEKGLQ 135 Query: 501 SVEDVDVVLNDEKISCAPMSDFGGDTKRKKIYVRLLLSIDRRETTSAALDTVNLALELKD 680 + DF I ++L+ R+ + + + K Sbjct: 136 KAQ----------------RDFN-------IVAKVLICGMRQSSKQLTKEIFRQINQAKS 172 Query: 681 EGVIGIDLSGNPVVGEWETYLPALERAKELGIPTTIHCGEVPNRKEIQAMLDFCPQRLGH 860 G D +GN + + + L P T H GE I + +RLGH Sbjct: 173 LEFAGFDFAGNEHDFPPQEIADLIRFTQRLDRPMTFHAGECGCPSHIAQSIALGIKRLGH 232 Query: 861 VCCLDD--EEWKKLKSSMIPVEICLTSNVMTGGTPSLELHHFADLYNAKHPLSICTDDSG 1034 V + D E + + E+CLTSN+ T SL + +LY A ++I TD+ Sbjct: 233 VTAIHDHPELIADFVENKVTAELCLTSNLQTKAAKSLAEFPYQELYEAGAKITINTDNRT 292 Query: 1035 LFSTSLSNEYYLVASTFGLSKAELFRLAQSAVEFVFADDEVKKSLRAAFEHA 1190 + +T+L+ EY L FG S A+ + Q+A+E FA + K L A + A Sbjct: 293 VSNTNLTKEYQLFVDYFGTSLADFYHFNQNAIEASFASEAEKAELLAELKKA 344
>Q9CIR9:ADD_LACLA Adenosine deaminase - Lactococcus lactis subsp. lactis (Streptococcus| lactis) Length = 352 Score = 109 bits (273), Expect = 2e-23 Identities = 90/349 (25%), Positives = 158/349 (45%), Gaps = 7/349 (2%) Frame = +3 Query: 156 LPKVELHAHLNGSVRNSTLLELAKELGDKGVIVYEDV--KDVIMKNDRSLPECFRLFDLF 329 +PKVELH HL+GS+ S + ELAK G + E++ K +N ++L E + FD Sbjct: 18 MPKVELHCHLDGSLSLSVIKELAKNAGIHMTMSDEEILEKAQAPENTKNLLEYLQRFDFV 77 Query: 330 HILTTDHDTVTRIAKEVIGDFAAENVVYLEIRTTPKNNEAKGMTKRSYMNAVVKGLKSVE 509 L + + A +V+ A +N+ Y+EIR P + + +T + AV+ GL E Sbjct: 78 LPLLQTYKNLELAAYDVVRQAANDNIKYIEIRFAPSQHLLENLTLEEAVEAVIAGLSRAE 137 Query: 510 DVDVVLNDEKISCAPMSDFGGDTKRKKIYVRLLLSIDRRETTSAALDTVNLALELKDEGV 689 +DF I L+ ++E + L ++ DE + Sbjct: 138 ----------------NDF-------DIRANALVCGLKQEPIQKLQKLLPLFDKIPDEHL 174 Query: 690 IGIDLSGNPVVGEWETYLPALERAKELGIPTTIHCGEVPN-RKEIQAMLDFCPQRLGHVC 866 +G D++G+ + E ++ + K G+ T+H GE P K I + R+GH Sbjct: 175 VGFDMAGDELNYPQEKFVDLIHDIKIKGVNVTLHAGECPACEKNILDSIAMGASRIGHGI 234 Query: 867 C---LDDEEWKKLKSSMIPVEICLTSNVMTGGTPSLELHHFADLYNAKHPLSICTDDSGL 1037 L + E K + I +E+ TSN T L + F +LY+ +++ TD+ + Sbjct: 235 MTKNLSEAEQKMMIEKQIVLEMAPTSNFQTKAVTELAQYPFKELYDKGIHVTLNTDNRMV 294 Query: 1038 FSTSLSNEYYLVASTF-GLSKAELFRLAQSAVEFVFADDEVKKSLRAAF 1181 +T+LS EY +++ + S ++ ++ A++ F E K+ L F Sbjct: 295 SATNLSKEYEKISAWYPDFSLSDFEKINHYAIDGAFIGQEEKEELHQRF 343
>Q97EV1:ADD_CLOAB Adenosine deaminase - Clostridium acetobutylicum| Length = 334 Score = 109 bits (273), Expect = 2e-23 Identities = 92/348 (26%), Positives = 158/348 (45%), Gaps = 8/348 (2%) Frame = +3 Query: 150 VALPKVELHAHLNGSVRNSTLLELAKELGDKGVIVYEDVKDV-----IMKNDRSLPECFR 314 + LPKVELH HL+GS+R T+L+L L + I YE+ +D I KN SL E Sbjct: 8 INLPKVELHCHLDGSLRPETVLDLC--LKENINIPYENPEDFKSSLKISKNCSSLKEYLE 65 Query: 315 LFDLFHILTTDHDTVTRIAKEVIGDFAAENVVYLEIRTTPKNNEAKGMTKRSYMNAVVKG 494 F + + + R+ E++ D + + Y EIR P + + + + + A ++ Sbjct: 66 KFYFPIRVMQKKENIYRVTMELLEDSKKDGIEYTEIRFAPFQHTEQDLNENDVVEAALEA 125 Query: 495 LKSVEDVDVVLNDEKISCAPMSDFGGDTKRKKIYVRLLLSIDRRETTSAALDTVNLALEL 674 L+ E + I+ L+L R + ++D VNLA Sbjct: 126 LQDGES-----------------------KLGIHSNLILCSLRHDPVERSIDLVNLANSY 162 Query: 675 KDEGVIGIDLSGNPVVGEWETYLPALERAKELGIPTTIHCGEVPNRKEIQAMLDFC-PQR 851 +EGV +DL+GN E + A + A + GI TIH GE + I + R Sbjct: 163 -NEGVCAVDLAGNESDFPPELHKEAFDLAYDNGIKITIHAGETGIAENILKSIKLLHADR 221 Query: 852 LGH--VCCLDDEEWKKLKSSMIPVEICLTSNVMTGGTPSLELHHFADLYNAKHPLSICTD 1025 +GH +E + + + +P+E+C SNV T + + H F ++ +++ TD Sbjct: 222 IGHGIFAYKSEEILQYVIENQVPLEMCPKSNVDTKAVKNYKNHPFKKYFDLGVKVTLNTD 281 Query: 1026 DSGLFSTSLSNEYYLVASTFGLSKAELFRLAQSAVEFVFADDEVKKSL 1169 + + + SL +EY +A+ F E+ + ++ + FA +E K +L Sbjct: 282 NRTVSNVSLVDEYLNLANIFDFGIEEIKTVIRNGISASFATEEFKVNL 329
>P63907:ADD_MYCTU Adenosine deaminase - Mycobacterium tuberculosis| Length = 365 Score = 108 bits (270), Expect = 5e-23 Identities = 96/352 (27%), Positives = 159/352 (45%), Gaps = 24/352 (6%) Frame = +3 Query: 159 PKVELHAHLNGSVRNSTLLELAKELGDKGVIVYEDVK--DV--------IMKNDRSLPEC 308 PK LH HL+G +R +T+L++A ++G Y+D+ DV + SL Sbjct: 14 PKALLHDHLDGGLRPATVLDIAGQVG------YDDLPATDVDALASWFRTQSHSGSLERY 67 Query: 309 FRLFDLFHILTTDHDTVTRIAKEVIGDFAAENVVYLEIRTTPKNNEAKGMTKRSYMNAVV 488 F + + + R+A E D AA++VVY E+R P+ + + G++ ++ V+ Sbjct: 68 LEPFSHTVAVMQTPEALYRVAFECAQDLAADSVVYAEVRFAPELHISCGLSFDDVVDTVL 127 Query: 489 KGLKSVEDVDVVLNDEKISCAPMSDFGGDTKRKKIYVRLLLSIDRRETTSAALDTVNLAL 668 G + E +CA + I VR L++ R S + LA+ Sbjct: 128 TGFAAGEK----------ACA--------ADGQPITVRCLVTAMRHAAMSREI--AELAI 167 Query: 669 ELKDEGVIGIDLSGNPVVGEWETYLPALERAKELGIPTTIHCGEVPNRKEIQAMLDFC-P 845 +D+GV+G D++G +L A E ++ TIH GE I + FC Sbjct: 168 RFRDKGVVGFDIAGAEAGHPPTRHLDAFEYMRDHNARFTIHAGEAFGLPSIHEAIAFCGA 227 Query: 846 QRLGH-VCCLDDEEWKK------------LKSSMIPVEICLTSNVMTGGTPSLELHHFAD 986 RLGH V +DD + L+ IP+E+C +SNV TG S+ H F Sbjct: 228 DRLGHGVRIVDDIDVDADGGFQLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDL 287 Query: 987 LYNAKHPLSICTDDSGLFSTSLSNEYYLVASTFGLSKAELFRLAQSAVEFVF 1142 L A+ +++ TD+ + TS+S E + + FG ++L R +A++ F Sbjct: 288 LARARFRVTVNTDNRLMSDTSMSLEMHRLVEAFGYGWSDLARFTVNAMKSAF 339
>P63908:ADD_MYCBO Adenosine deaminase - Mycobacterium bovis| Length = 365 Score = 108 bits (270), Expect = 5e-23 Identities = 96/352 (27%), Positives = 159/352 (45%), Gaps = 24/352 (6%) Frame = +3 Query: 159 PKVELHAHLNGSVRNSTLLELAKELGDKGVIVYEDVK--DV--------IMKNDRSLPEC 308 PK LH HL+G +R +T+L++A ++G Y+D+ DV + SL Sbjct: 14 PKALLHDHLDGGLRPATVLDIAGQVG------YDDLPATDVDALASWFRTQSHSGSLERY 67 Query: 309 FRLFDLFHILTTDHDTVTRIAKEVIGDFAAENVVYLEIRTTPKNNEAKGMTKRSYMNAVV 488 F + + + R+A E D AA++VVY E+R P+ + + G++ ++ V+ Sbjct: 68 LEPFSHTVAVMQTPEALYRVAFECAQDLAADSVVYAEVRFAPELHISCGLSFDDVVDTVL 127 Query: 489 KGLKSVEDVDVVLNDEKISCAPMSDFGGDTKRKKIYVRLLLSIDRRETTSAALDTVNLAL 668 G + E +CA + I VR L++ R S + LA+ Sbjct: 128 TGFAAGEK----------ACA--------ADGQPITVRCLVTAMRHAAMSREI--AELAI 167 Query: 669 ELKDEGVIGIDLSGNPVVGEWETYLPALERAKELGIPTTIHCGEVPNRKEIQAMLDFC-P 845 +D+GV+G D++G +L A E ++ TIH GE I + FC Sbjct: 168 RFRDKGVVGFDIAGAEAGHPPTRHLDAFEYMRDHNARFTIHAGEAFGLPSIHEAIAFCGA 227 Query: 846 QRLGH-VCCLDDEEWKK------------LKSSMIPVEICLTSNVMTGGTPSLELHHFAD 986 RLGH V +DD + L+ IP+E+C +SNV TG S+ H F Sbjct: 228 DRLGHGVRIVDDIDVDADGGFQLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDL 287 Query: 987 LYNAKHPLSICTDDSGLFSTSLSNEYYLVASTFGLSKAELFRLAQSAVEFVF 1142 L A+ +++ TD+ + TS+S E + + FG ++L R +A++ F Sbjct: 288 LARARFRVTVNTDNRLMSDTSMSLEMHRLVEAFGYGWSDLARFTVNAMKSAF 339
>Q6DG22:ADA_DANRE Adenosine deaminase - Danio rerio (Zebrafish) (Brachydanio rerio)| Length = 359 Score = 106 bits (264), Expect = 3e-22 Identities = 93/346 (26%), Positives = 166/346 (47%), Gaps = 9/346 (2%) Frame = +3 Query: 159 PKVELHAHLNGSVRNSTLLELAKELG-DKGVIVYEDVKDVIMKND-RSLPECFRLFDLF- 329 PKVELH HL+G++R T+L++AK G V + E++K++ N+ +L E F F Sbjct: 10 PKVELHVHLDGAIRLKTVLDVAKRRGISLPVSMEEELKELCTVNEPATLTEFLGKFSHFM 69 Query: 330 HILTTDHDTVTRIAKEVIGDFAAENVVYLEIRTTPKNNEAKGMTKRSYMNAVVKGLKSVE 509 H++ D + + RIA E + A E V+Y+E R +P KG+ + G + + Sbjct: 70 HVIAGDREAIKRIAYEFVETKAKEGVIYVEARYSPHFLANKGVEPLPWDQK--PGDITPD 127 Query: 510 DVDVVLNDEKISCAPMSDFGGDTKRKKIYVRLLLSIDRRETTSAALDTVNLALELKDEGV 689 DV ++N F + K R +L R + +++ V L + +GV Sbjct: 128 DVVDLVN---------QGFKEGEQAFKTKARSILCC-MRHMPNWSMEVVELCKKFHKDGV 177 Query: 690 IGIDLSGNPVVG--EWETYLPALERAKELGIPTTIHCGEVPNRKEIQAMLDFC-PQRLGH 860 + IDL+G+ + + + A E A + T+H GEV ++ ++ +R+GH Sbjct: 178 VAIDLAGDESMNCESYPGHKKAFEEAVRSNVHRTVHAGEVGPASVVREAVEVLKAERIGH 237 Query: 861 -VCCLDDEE-WKKLKSSMIPVEICLTSNVMTGG-TPSLELHHFADLYNAKHPLSICTDDS 1031 L+D+ +K+L + E+C S+ +TG P H K S+ TDD Sbjct: 238 GYHTLEDQNLYKQLLHQNMHFEMCPVSSRLTGACEPDFTKHPLITFKKDKANYSLNTDDP 297 Query: 1032 GLFSTSLSNEYYLVASTFGLSKAELFRLAQSAVEFVFADDEVKKSL 1169 +F+++L+++Y +V ++ E RL +A + F ++ K+ L Sbjct: 298 TIFNSTLNSDYEVVQKYMDFTEEEFKRLNINAAKSCFLPEKEKEKL 343
>Q9CCL9:ADD_MYCLE Adenosine deaminase - Mycobacterium leprae| Length = 362 Score = 105 bits (263), Expect = 3e-22 Identities = 94/348 (27%), Positives = 159/348 (45%), Gaps = 20/348 (5%) Frame = +3 Query: 159 PKVELHAHLNGSVRNSTLLELAKELG-DKGVIVYEDVKDV-----IMKNDRSLPECFRLF 320 PK LH HL+G +R +T+L++A ++G D+ + DV+ + + SL F Sbjct: 14 PKALLHDHLDGGLRPATVLDIAGQVGYDR--LPATDVESLETWFRTASHSGSLERYLEPF 71 Query: 321 DLFHILTTDHDTVTRIAKEVIGDFAAENVVYLEIRTTPKNNEAKGMTKRSYMNAVVKGLK 500 + + + R+A E + D AA++VVY E+R P+ + +G++ + +V+ G Sbjct: 72 SHTVAVMQTPEALHRVAYECVEDLAADSVVYAEVRFAPELHIDEGLSFDEVLASVLAGFA 131 Query: 501 SVEDVDVVLNDEKISCAPMSDFGGDTKRKKIYVRLLLSIDRRETTSAALDTVNLALELKD 680 D + +CA + I VR L++ R S + LA+ +D Sbjct: 132 ----------DGERACA--------AEGNAITVRCLVTAMRHAAMSREI--AELAIRFRD 171 Query: 681 EGVIGIDLSGNPVVGEWETYLPALERAKELGIPTTIHCGEVPNRKEIQAMLDFC-PQRLG 857 +GV+G D++G +L A E + TIH GE I + FC RLG Sbjct: 172 KGVVGFDIAGAEAGHPPTRHLDAFEYMRSNNARFTIHAGEAFGLPSIHEAIAFCGADRLG 231 Query: 858 H-VCCLDDEEWKK------------LKSSMIPVEICLTSNVMTGGTPSLELHHFADLYNA 998 H V +DD + L+ IP+E+C +SN+ TG S+ H F L A Sbjct: 232 HGVRIVDDIDVDPGGGIRLGPLASILRDKRIPLELCPSSNLQTGAVASITEHPFDLLAWA 291 Query: 999 KHPLSICTDDSGLFSTSLSNEYYLVASTFGLSKAELFRLAQSAVEFVF 1142 + +++ TD+ + TS+S E + + FG +L R +A++ F Sbjct: 292 RFRVTVNTDNRLMSDTSMSLEMHRLVEAFGYGWGDLERFTINAMKSAF 339
>Q8UJ05:ADD_AGRT5 Adenosine deaminase - Agrobacterium tumefaciens (strain C58 / ATCC| 33970) Length = 325 Score = 105 bits (261), Expect = 6e-22 Identities = 84/350 (24%), Positives = 156/350 (44%), Gaps = 10/350 (2%) Frame = +3 Query: 156 LPKVELHAHLNGSVRNSTLLELAKELG-------DKGVIVYEDVKDVIMKNDRSLPECFR 314 L K E+H HL G+ + +++ A++ G G V+ D + I D ++ + F+ Sbjct: 5 LLKAEIHCHLEGAAPPALVVKQAEKYGIDTSGFLRDGQYVWSDFAEFIQCYD-AVAQVFK 63 Query: 315 LFDLFHILTTDHDTVTRIAKEVIGDFAAENVVYLEIRTTPKNNEAKGMTKRSYMNAVVKG 494 + + +LT + T + A N +Y E+ +P + + G+ +Y+ V +G Sbjct: 64 SDEDYAVLTETYLT----------ELAEANTIYSELIISPDHGDRIGLGADAYLAGVAEG 113 Query: 495 LKSVEDVDVVLNDEKISCAPMSDFGGDTKRKKIYVRLLLSIDRRETTSAALDTVNLALEL 674 ++ ++ + I R++++ +R + A + Sbjct: 114 IRIAKE-----------------------KTGIETRIIVTGERHFGPERVIAAAEYAARI 150 Query: 675 KDEGVIGIDLSGNPVVGEWETYLPALERAKELGIPTTIHCGEVPNRKEIQAMLDFC-PQR 851 + V G +++G +G Y A + A++ G+ TIH GEV + + LD P R Sbjct: 151 RHPLVTGFNMAGEERMGRVADYARAFDIARDAGLGLTIHAGEVCGPESVADALDLVKPSR 210 Query: 852 LGH-VCCLDDEEW-KKLKSSMIPVEICLTSNVMTGGTPSLELHHFADLYNAKHPLSICTD 1025 +GH V ++D +L + +E+C SN+ P H L +A + I +D Sbjct: 211 IGHGVRAIEDAALISRLVETGTVLEVCPGSNIALSVYPDFASHPLKALSDAGVRVCISSD 270 Query: 1026 DSGLFSTSLSNEYYLVASTFGLSKAELFRLAQSAVEFVFADDEVKKSLRA 1175 D F TSL+ EY L A FG + AE+ R+ ++A+E F D+ ++ L A Sbjct: 271 DPPFFFTSLAREYALAADAFGFNDAEINRMTRTALECAFVDEATRERLLA 320
>P03958:ADA_MOUSE Adenosine deaminase - Mus musculus (Mouse)| Length = 352 Score = 103 bits (257), Expect = 2e-21 Identities = 98/359 (27%), Positives = 166/359 (46%), Gaps = 22/359 (6%) Frame = +3 Query: 159 PKVELHAHLNGSVRNSTLLELAKELGDK-GVIVYEDVKDVI-MKNDRSLPECFRLFDLFH 332 PKVELH HL+G+++ T+L K+ G E+++++I M SLP FD + Sbjct: 10 PKVELHVHLDGAIKPETILYFGKKRGIALPADTVEELRNIIGMDKPLSLPGFLAKFDYYM 69 Query: 333 -ILTTDHDTVTRIAKEVIGDFAAENVVYLEIRTTPKN-----------NEAKG-MTKRSY 473 ++ + + RIA E + A E VVY+E+R +P N+ +G +T Sbjct: 70 PVIAGCREAIKRIAYEFVEMKAKEGVVYVEVRYSPHLLANSKVDPMPWNQTEGDVTPDDV 129 Query: 474 MNAVVKGLKSVEDVDVVLNDEKISCAPMSDFGGDTKRKKIYVRLLLSIDRRETTSAALDT 653 ++ V +GL+ E FG I VR +L R + S +L+ Sbjct: 130 VDLVNQGLQEGEQA----------------FG-------IKVRSILCCMRHQP-SWSLEV 165 Query: 654 VNLALELKDEGVIGIDLSGNPVVGEWETYLP----ALERAKELGIPTTIHCGEVPNRKEI 821 + L + + V+ +DL+G+ + E + P A E A + GI T+H GEV + + + Sbjct: 166 LELCKKYNQKTVVAMDLAGDETI-EGSSLFPGHVEAYEGAVKNGIHRTVHAGEVGSPEVV 224 Query: 822 QAMLDFCP-QRLGH-VCCLDDEE-WKKLKSSMIPVEICLTSNVMTGGTPSLELHHFADLY 992 + +D +R+GH ++DE + +L + E+C S+ +TG H Sbjct: 225 REAVDILKTERVGHGYHTIEDEALYNRLLKENMHFEVCPWSSYLTGAWDPKTTHAVVRFK 284 Query: 993 NAKHPLSICTDDSGLFSTSLSNEYYLVASTFGLSKAELFRLAQSAVEFVFADDEVKKSL 1169 N K S+ TDD +F ++L +Y + G ++ E RL +A + F +E KK L Sbjct: 285 NDKANYSLNTDDPLIFKSTLDTDYQMTKKDMGFTEEEFKRLNINAAKSSFLPEEEKKEL 343
>Q98GV2:ADD_RHILO Adenosine deaminase - Rhizobium loti (Mesorhizobium loti)| Length = 324 Score = 102 bits (254), Expect = 4e-21 Identities = 89/354 (25%), Positives = 154/354 (43%), Gaps = 10/354 (2%) Frame = +3 Query: 162 KVELHAHLNGSVRNSTLLELAKELG-------DKGVIVYEDVKDVIMKNDRSLPECFRLF 320 K ELH H+ G+ ++ A++ G G V+ D + D S E FR Sbjct: 4 KAELHCHIEGAAAPELVIRQAQKYGKDTAPYIQNGSFVWHDFTSFLAAYDFSA-ELFR-- 60 Query: 321 DLFHILTTDHDTVTRIAKEVIGDFAAENVVYLEIRTTPKNNEAKGMTKRSYMNAVVKGLK 500 T+ D R+A + A + +Y E+ T+P + G++ ++Y +A+ +G+ Sbjct: 61 -------TEED-YARLADHYLTSLARDGAIYSEVFTSPDHATKAGLSPKAYTDALGEGML 112 Query: 501 SVEDVDVVLNDEKISCAPMSDFGGDTKRKKIYVRLLLSIDRRETTSAALDTVNLALELKD 680 + + I R++++ R + A + Sbjct: 113 RAK-----------------------AKTGIEGRMIVTGVRHVGVESIERAARFAARCGN 149 Query: 681 EGVIGIDLSGNPVVGEWETYLPALERAKELGIPTTIHCGEVPNRKEIQAMLDFC-PQRLG 857 V G ++G+ VGE E Y+ A E A+E G+ TIH GE+ + +QA LD P R+G Sbjct: 150 PLVTGFGVAGDERVGEMEDYVRAFEIAREAGLGITIHAGELTGWETVQAALDHIRPSRIG 209 Query: 858 H-VCCLDDEEW-KKLKSSMIPVEICLTSNVMTGGTPSLELHHFADLYNAKHPLSICTDDS 1031 H V +++ + +++ I +E C SN+ S H L A +++ +DD Sbjct: 210 HGVRAIENPDLVRRIADEGIVLECCPGSNIALKVFDSFADHPLPALQAAGCKVTLNSDDP 269 Query: 1032 GLFSTSLSNEYYLVASTFGLSKAELFRLAQSAVEFVFADDEVKKSLRAAFEHAA 1193 F TSL EY + A F +++ L + ++A+E F D + K +L A AA Sbjct: 270 PYFWTSLKREYDIAAEHFAMNEKALAAVTRTAIEAAFVDRKTKAALLARLNGAA 323
>Q9AK25:ADD5_STRCO Probable adenosine deaminase 5 - Streptomyces coelicolor| Length = 396 Score = 102 bits (254), Expect = 4e-21 Identities = 105/387 (27%), Positives = 164/387 (42%), Gaps = 24/387 (6%) Frame = +3 Query: 54 TSRAPGRRRSKTKPAAMGTQTSEAEKEMRAWCVALPKVELHAHLNGSVRNSTLLELAKEL 233 TSR+ + + PAA+ ++T ++ RA PKV LH HL+G +R T++ELA+E Sbjct: 2 TSRST-EKSAAANPAAV-SKTPSPDRIRRA-----PKVLLHDHLDGGLRPGTIVELARET 54 Query: 234 GDKGVIVYEDVKDVIMK----------NDRSLPECFRLFDLFHILTTDHDTVTRIAKEVI 383 G Y D+ + + SL F + D + R+A E Sbjct: 55 G------YGDLPETDADLLGTWFRQAADSGSLERYLETFSHTVGVMQTRDALVRVAAECA 108 Query: 384 GDFAAENVVYLEIRTTPKNNEAKGMTKRSYMNAVVKGLKSVEDVDVVLNDEKISCAPMSD 563 D A + VVY E+R P+ + KG+T + AV +G + E D Sbjct: 109 EDLAEDGVVYAEVRYAPEQHLEKGLTLEEVVEAVNEGFREGE-------------RRARD 155 Query: 564 FGGDTKRKKIYVRLLLSIDRRETTSAALDTVNLALELKDEGVIGIDLSGNPVVGEWETYL 743 G +I V LL+ R S L+ LA +D GV+G D++G +L Sbjct: 156 NG-----HRIRVGALLTAMRHAARS--LEIAELANRYRDLGVVGFDIAGAEAGYPPTRHL 208 Query: 744 PALERAKELGIPTTIHCGEVPNRKEIQAMLDFC-PQRLGH-VCCLDDEEWKK-------- 893 A E K TIH GE I L +C RLGH V +DD + + Sbjct: 209 DAFEYLKRENNHFTIHAGEAFGLPSIWQALQWCGADRLGHGVRIIDDIQVHEDGSVKLGR 268 Query: 894 ----LKSSMIPVEICLTSNVMTGGTPSLELHHFADLYNAKHPLSICTDDSGLFSTSLSNE 1061 ++ IP+E+C +SN+ TG S H L ++ TD+ + TS+S E Sbjct: 269 LASYVRDKRIPLELCPSSNLQTGAADSYAEHPIGLLRRLHFRATVNTDNRLMSHTSMSRE 328 Query: 1062 YYLVASTFGLSKAELFRLAQSAVEFVF 1142 + + FG + ++ + +A++ F Sbjct: 329 FEHLVEAFGYTLDDMQWFSVNAMKSAF 355
>P56658:ADA_BOVIN Adenosine deaminase - Bos taurus (Bovine)| Length = 363 Score = 101 bits (251), Expect = 8e-21 Identities = 96/359 (26%), Positives = 169/359 (47%), Gaps = 22/359 (6%) Frame = +3 Query: 159 PKVELHAHLNGSVRNSTLLELAKELGDK-GVIVYEDVKDVI-MKNDRSLPECFRLFDLFH 332 PKVELH HL+G+++ T+L ++ G E+++++I M SLPE FD + Sbjct: 10 PKVELHVHLDGAIKPETILYYGRKRGIALPADTPEELQNIIGMDKPLSLPEFLAKFDYYM 69 Query: 333 -ILTTDHDTVTRIAKEVIGDFAAENVVYLEIRTTPKN-----------NEAKG-MTKRSY 473 + + V RIA E + A + VVY+E+R +P N+A+G +T Sbjct: 70 PAIAGCREAVKRIAYEFVEMKAKDGVVYVEVRYSPHLLANSKVEPIPWNQAEGDLTPDEV 129 Query: 474 MNAVVKGLKSVEDVDVVLNDEKISCAPMSDFGGDTKRKKIYVRLLLSIDRRETTSAALDT 653 ++ V +GL+ E DFG + VR +L R + + ++ + Sbjct: 130 VSLVNQGLQEGE----------------RDFG-------VKVRSILCCMRHQPSWSS-EV 165 Query: 654 VNLALELKDEGVIGIDLSGNPVVGEWETYLP----ALERAKELGIPTTIHCGEVPNRKEI 821 V L + +++ V+ IDL+G+ + E + P A A + G+ T+H GEV + + Sbjct: 166 VELCKKYREQTVVAIDLAGDETI-EGSSLFPGHVKAYAEAVKSGVHRTVHAGEVGSANVV 224 Query: 822 QAMLDFCP-QRLGH-VCCLDDEE-WKKLKSSMIPVEICLTSNVMTGGTPSLELHHFADLY 992 + +D +RLGH L+D + +L+ + E+C S+ +TG H Sbjct: 225 KEAVDTLKTERLGHGYHTLEDATLYNRLRQENMHFEVCPWSSYLTGAWKPDTEHPVVRFK 284 Query: 993 NAKHPLSICTDDSGLFSTSLSNEYYLVASTFGLSKAELFRLAQSAVEFVFADDEVKKSL 1169 N + S+ TDD +F ++L +Y + + G ++ E RL +A + F ++ KK L Sbjct: 285 NDQVNYSLNTDDPLIFKSTLDTDYQMTKNEMGFTEEEFKRLNINAAKSSFLPEDEKKEL 343
>Q9X7T2:ADD2_STRCO Probable adenosine deaminase 2 - Streptomyces coelicolor| Length = 359 Score = 100 bits (249), Expect = 1e-20 Identities = 90/357 (25%), Positives = 155/357 (43%), Gaps = 19/357 (5%) Frame = +3 Query: 156 LPKVELHAHLNGSVRNSTLLELAKELGDKGVIVYEDVKDVIM-----KNDRSLPECFRLF 320 LPK LH HL+G +R +T++ELA+ +G + D ++ N L F Sbjct: 14 LPKAVLHDHLDGGLRPATVVELARSVGH--TLPTTDPDELAAWYYEAANSGDLVRYIATF 71 Query: 321 DLFHILTTDHDTVTRIAKEVIGDFAAENVVYLEIRTTPKNNEAKGMTKRSYMNAVVKGLK 500 + + + + + R A+E + D AA+ VVY E+R P+ N G++ R + V +GL Sbjct: 72 EHTLAVMQNREGLLRAAEEYVLDLAADGVVYGEVRYAPELNTRGGLSMREVVETVQEGLA 131 Query: 501 SVEDVDVVLNDEKISCAPMSDFGGDTKRKKIYVRLLLSIDRRETTSAALDTVNLALELKD 680 + K + A G R + + DR + +LA+ +D Sbjct: 132 T--------GMAKAAAA------GTPVRVGTLLCGMRMFDR------VREAADLAVAFRD 171 Query: 681 EGVIGIDLSGNPVVGEWETYLPALERAKELGIPTTIHCGEVPNRKEIQAMLDFC-PQRLG 857 GV+G D++G +L A E + +P TIH GE I L C QR+G Sbjct: 172 AGVVGFDIAGAEDGFPPADHLDAFEHLRRENVPFTIHAGEAHGLPSIHQALQVCGAQRIG 231 Query: 858 HVCCLDDE-------------EWKKLKSSMIPVEICLTSNVMTGGTPSLELHHFADLYNA 998 H + D+ W ++ I +E+C TSN+ TG S+ H L + Sbjct: 232 HGVRITDDIPDLAAGKLGRLAAW--VRDRRIALEMCPTSNLQTGAATSIAEHPITALKDL 289 Query: 999 KHPLSICTDDSGLFSTSLSNEYYLVASTFGLSKAELFRLAQSAVEFVFADDEVKKSL 1169 +++ TD+ + T+++ E L+ G S +L + +A++ F + + +L Sbjct: 290 GFRVTLNTDNRLVSGTTMTREMSLLVEQAGWSVEDLRTVTVNALKSAFVPFDERTAL 346
>Q8E8D4:ADD_SHEON Adenosine deaminase - Shewanella oneidensis| Length = 331 Score = 100 bits (248), Expect = 2e-20 Identities = 91/353 (25%), Positives = 155/353 (43%), Gaps = 11/353 (3%) Frame = +3 Query: 153 ALPKVELHAHLNGSVRNSTLLELAKELGDKGVIVYEDVKDV------IMKNDRSLPECFR 314 ++P V+LH HL+G+VR +T+ EL + G+ + D + I + SL + Sbjct: 5 SIPLVDLHRHLDGNVRVNTIWELGHQ---HGIALPADSLETLAPFVQIQGKETSLVAFLK 61 Query: 315 LFDLFHILTTDHDTVTRIAKEVIGDFAAENVVYLEIRTTPKNNEAKG-MTKRSYMNAVVK 491 D + D D V RIA E + D A + Y E+R +P + + AV+ Sbjct: 62 KLDWMVAVLADLDAVKRIAYENVADAALSGLDYAELRFSPYYMAMNHKLPIEGVVEAVID 121 Query: 492 GLKS-VEDVDVVLNDEKISCAPMSDFGGDTKRKKIYVRLLLSIDRRETTSAALDTVNLAL 668 G+K+ ++D V +N L+ I R A L Sbjct: 122 GVKAGLKDYQVNIN-------------------------LIGIMSRSFGQPACTQELEGL 156 Query: 669 ELKDEGVIGIDLSGNPVVGEWETYLPALERAKELGIPTTIHCGEVPNRKEI-QAMLDFCP 845 + ++ +DL+G+ + E + +R ++ G+ T H GE + + QA+ + Sbjct: 157 LAHKQHLVAMDLAGDELGFPGELFNEHFKRVRDAGLAITAHAGEAAGSQSMWQAIQELGA 216 Query: 846 QRLGH-VCCLDDEEWKK-LKSSMIPVEICLTSNVMTGGTPSLELHHFADLYNAKHPLSIC 1019 R+GH V + D + + L I +E C TSN+ T S H F +A + + Sbjct: 217 TRIGHGVNAIHDPKLMEYLAKHRIGIESCPTSNLHTSTVSSYAEHPFRTFMDAGVLIGLN 276 Query: 1020 TDDSGLFSTSLSNEYYLVASTFGLSKAELFRLAQSAVEFVFADDEVKKSLRAA 1178 TDD G+ + + +EY + GLS AEL ++ ++ VE F + +K+L AA Sbjct: 277 TDDPGVSAIDIKHEYRIAKFELGLSDAELAQVQRNGVEMAFLSESERKALYAA 329
>Q5ZKP6:ADA_CHICK Adenosine deaminase - Gallus gallus (Chicken)| Length = 357 Score = 99.4 bits (246), Expect = 3e-20 Identities = 93/356 (26%), Positives = 161/356 (45%), Gaps = 19/356 (5%) Frame = +3 Query: 159 PKVELHAHLNGSVRNSTLLELAKELGD--KGVIVYEDVKDVIMKNDRSLPECFRLFDLF- 329 PKVELH HL+G++R T+L K+ G G V E +K V + SL F+ + Sbjct: 11 PKVELHIHLDGAIRPETILHFGKKRGVPLPGSTVDELMKHVSYQTPLSLKLFLEKFNHYM 70 Query: 330 HILTTDHDTVTRIAKEVIGDFAAENVVYLEIRTTPKN-----------NEAKG-MTKRSY 473 + D + V RIA E++ A E VVY+E+R +P +A+G +T Sbjct: 71 PAIAGDREAVRRIAYELVETKAKEGVVYVEVRYSPHLLANCRVEPIPWGQAEGDLTPEEV 130 Query: 474 MNAVVKGLKSVEDVDVVLNDEKISCAPMSDFGGDTKRKKIYVRLLLSIDRRETTSAALDT 653 +N V +GL+ E + +I R +L R S + + Sbjct: 131 VNLVNQGLQDGE-----------------------RNFRIKARSILCC-MRHMPSWSPEV 166 Query: 654 VNLALELKDEGVIGIDLSGNPVVGEWETYLPALERAKELGIPTTIHCGEV-PNRKEIQAM 830 V L + ++ V+ IDL+G+ ++ + A E A+ GI T+H GE P +A+ Sbjct: 167 VELCKKYQNNSVVAIDLAGDELLMASSDHKAAYEEAERCGIHRTVHAGEAGPATMIKEAV 226 Query: 831 LDFCPQRLGHVCCL--DDEEWKKLKSSMIPVEICLTSNVMTGG-TPSLELHHFADLYNAK 1001 +R+GH + D E +++L + + E+C S+ +TG P H + Sbjct: 227 YLLKAERIGHGYHVLEDPELYRELLRTRMHFEVCPWSSYLTGACLPDFRKHPVVQFKKDQ 286 Query: 1002 HPLSICTDDSGLFSTSLSNEYYLVASTFGLSKAELFRLAQSAVEFVFADDEVKKSL 1169 SI TDD +F++++ +Y +V ++ + R+ +A + F ++ K+ L Sbjct: 287 ANYSINTDDPLIFNSNIDKDYGIVKEYMDFTEEDFKRVNINAAQSSFLPEKEKQEL 342
>Q7VNV1:ADD_HAEDU Adenosine deaminase - Haemophilus ducreyi| Length = 344 Score = 99.0 bits (245), Expect = 4e-20 Identities = 88/349 (25%), Positives = 157/349 (44%), Gaps = 12/349 (3%) Frame = +3 Query: 165 VELHAHLNGSVRNSTLLELAKELG-------DKGVIVYEDVKDVIMKNDRSLPECFRLFD 323 ++LH HL+GS+ + ++E AK+ + + Y V ++ L E R FD Sbjct: 11 IDLHLHLDGSLSPAWMIEWAKKQAVNLPASTAEALTAYVSVP----QDCSDLNEYLRCFD 66 Query: 324 LFHILTTDHDTVTRIAKEVIGDFAAENVVYLEIRTTPKNNEAKGMTKRSYMNAVVKGLKS 503 L L + ++ ++I + +VY EIR P+ + + M++ + A ++GL++ Sbjct: 67 LPLSLLQTPEALSSAVTDLIQRLDQDGLVYAEIRFAPQLHTQRSMSQEDAVKAALRGLQA 126 Query: 504 VEDVDVVLNDEKISCAPMSDFGGDTKRKKIYVRLLLSIDRRETTSAALDTVNLA---LEL 674 A S F + +L + + SA L+T+ LA L Sbjct: 127 -------------GLASTSLFKANL--------ILCCMRAADNRSANLETICLAKQYLTK 165 Query: 675 KDEGVIGIDLSGNPVVGEWETYLPALERAKELGIPTTIHCGEVPNRKEIQAMLDFCPQRL 854 + GV+ IDL+G + + + + A + G+P TIH GE + +Q LDF R+ Sbjct: 166 YEAGVVAIDLAGAEGLFATQHFQQEFDFANQRGVPFTIHAGEAAGPESVQQALDFGATRI 225 Query: 855 GH-VCCLDDEE-WKKLKSSMIPVEICLTSNVMTGGTPSLELHHFADLYNAKHPLSICTDD 1028 GH + ++ E K+L P+E+C SN+ T L + ++ TD+ Sbjct: 226 GHGIRAIESETVMKQLIDKRTPLEMCPCSNLQTKTVAQLADYPLRTFLMRGVVATLNTDN 285 Query: 1029 SGLFSTSLSNEYYLVASTFGLSKAELFRLAQSAVEFVFADDEVKKSLRA 1175 + T + EY L+A + LS +E +L +++ F +E KK+L A Sbjct: 286 MTVSQTCIQQEYRLLAEQYQLSISEAKQLLLNSIAAAFLSNEDKKALLA 334
>Q9KNI7:ADD_VIBCH Adenosine deaminase - Vibrio cholerae| Length = 334 Score = 97.8 bits (242), Expect = 9e-20 Identities = 89/348 (25%), Positives = 148/348 (42%), Gaps = 7/348 (2%) Frame = +3 Query: 153 ALPKVELHAHLNGSVRNSTLLELAKELGDK---GVIVYEDVKDVIMKNDRSLPECFRLFD 323 +LP +LH HL+G++R T+LEL ++ G K + I++ + SL D Sbjct: 5 SLPLTDLHRHLDGNIRTQTILELGQKFGVKLPANTLQTLTPYVQIVEAEPSLVAFLSKLD 64 Query: 324 LFHILTTDHDTVTRIAKEVIGDFAAENVVYLEIRTTPKNNEAK-GMTKRSYMNAVVKGLK 500 + D D R+A E + D + Y E+R +P K + + AVV G++ Sbjct: 65 WGVAVLGDLDACRRVAYENVEDALNARIDYAELRFSPYYMAMKHSLPVTGVVEAVVDGVR 124 Query: 501 SVEDVDVVLNDEKISCAPMSDFGGDTKRKKIYVRLLLSIDRRETTSAALDTVNLALELKD 680 A + DFG I L+ + R T A ++ L K+ Sbjct: 125 ----------------AGVRDFG-------IQANLIGIMSRTFGTDACQQELDAILSQKN 161 Query: 681 EGVIGIDLSGNPVVGEWETYLPALERAKELGIPTTIHCGEVPNRKEI-QAMLDFCPQRLG 857 ++ +DL+G+ + + ++ ++ ++ G+ T+H GE + + QA+ D R+G Sbjct: 162 H-IVAVDLAGDELGQPGDRFIQHFKQVRDAGLHVTVHAGEAAGPESMWQAIRDLGATRIG 220 Query: 858 H--VCCLDDEEWKKLKSSMIPVEICLTSNVMTGGTPSLELHHFADLYNAKHPLSICTDDS 1031 H D + L I +E CLTSN+ T SL H I TDD Sbjct: 221 HGVKAIHDPKLMDYLAQHRIGIESCLTSNLQTSTVDSLATHPLKRFLEHGILACINTDDP 280 Query: 1032 GLFSTSLSNEYYLVASTFGLSKAELFRLAQSAVEFVFADDEVKKSLRA 1175 + L EY + A GLS+ ++ + + +E F D KK+L A Sbjct: 281 AVEGIELPYEYEVAAPQAGLSQEQIRQAQLNGLELAFLSDSEKKALLA 328
>Q63ZU0:ADA_XENTR Adenosine deaminase - Xenopus tropicalis (Western clawed frog)| (Silurana tropicalis) Length = 358 Score = 97.8 bits (242), Expect = 9e-20 Identities = 93/346 (26%), Positives = 156/346 (45%), Gaps = 9/346 (2%) Frame = +3 Query: 159 PKVELHAHLNGSVRNSTLLELAKELGDK--GVIVYEDVKDVIMKNDRSLPECFRLFDLF- 329 PKVELH HL+GS++ T++ AK+ K V ++ V K SL E F+ + Sbjct: 9 PKVELHVHLDGSIKPETIIHFAKKRQIKLPADTVEGLLEHVSYKEPLSLTEFLSKFNHYM 68 Query: 330 HILTTDHDTVTRIAKEVIGDFAAENVVYLEIRTTPKNNEAKGMTKRSYMNAVVKGLKSVE 509 + D + + RIA E + A E V+Y+E+R +P N+ V+ + + Sbjct: 69 PAIAGDREAIKRIAYEFVEMKAKEGVIYVEVRYSP----------HFLANSKVEPIPWGQ 118 Query: 510 DVDVVLNDEKISCAPMSDFGGDTKRKKIYVRLLLSIDRRETTSAALDTVNLALELKDEGV 689 + DE + G+ K I R +L R S + + V L + +++ V Sbjct: 119 KEGDITPDEVVDLVNQGLRKGE-KAFNIKARSILCC-MRHMPSWSTEVVELCKKYQNDTV 176 Query: 690 IGIDLSGNPVVG--EWETYLPALERAKELGIPTTIHCGEV-PNRKEIQAMLDFCPQRLGH 860 + IDL+G+ + + + A E A + GI T+H GEV P+ +A+ +R+GH Sbjct: 177 VAIDLAGDESLNCESYPGHRKAYEEAVKCGIHRTVHAGEVGPSSVVKEAVEVLKAERIGH 236 Query: 861 --VCCLDDEEWKKLKSSMIPVEICLTSNVMTGGT-PSLELHHFADLYNAKHPLSICTDDS 1031 D +K+L + E+C S+ +TG P H K S+ TDD Sbjct: 237 GYHTTEDPNLYKELLEKNMHFEVCPWSSYLTGACHPDFTKHPATQFRKDKANYSLNTDDP 296 Query: 1032 GLFSTSLSNEYYLVASTFGLSKAELFRLAQSAVEFVFADDEVKKSL 1169 +F ++L +Y + A G ++ E R+ +A + F + KK L Sbjct: 297 LIFGSTLDVDYSIAAKHMGFTEEEFKRVNINAAKSSFLPESEKKEL 342
>Q920P6:ADA_RAT Adenosine deaminase - Rattus norvegicus (Rat)| Length = 352 Score = 97.8 bits (242), Expect = 9e-20 Identities = 95/359 (26%), Positives = 167/359 (46%), Gaps = 22/359 (6%) Frame = +3 Query: 159 PKVELHAHLNGSVRNSTLLELAKELG-DKGVIVYEDVKDVI-MKNDRSLPECFRLFDLFH 332 PKVELH HL+G+++ T+L K+ G D E ++++I M SLP+ FD + Sbjct: 10 PKVELHVHLDGAIKPETILYYGKKRGIDLPADTVEGLRNIIGMDKPLSLPDFLAKFDYYM 69 Query: 333 -ILTTDHDTVTRIAKEVIGDFAAENVVYLEIRTTPKN-----------NEAKG-MTKRSY 473 + + + RIA E + A E VVY+E+R +P N+A+G +T Sbjct: 70 PAIAGCREAIKRIAYEFVEMKAKEGVVYVEVRYSPHLLANSKVDPIPWNQAEGDLTPDEV 129 Query: 474 MNAVVKGLKSVEDVDVVLNDEKISCAPMSDFGGDTKRKKIYVRLLLSIDRRETTSAALDT 653 ++ V +GL+ E FG I VR +L R + S + + Sbjct: 130 VDLVNQGLQEGEQA----------------FG-------IKVRSILCCMRHQP-SWSPEV 165 Query: 654 VNLALELKDEGVIGIDLSGNPVVGEWETYLP----ALERAKELGIPTTIHCGEVPNRKEI 821 + L + + V+ +DL+G+ + E + P A E A + GI T+H GEV + + + Sbjct: 166 LELCKKYHQKTVVAMDLAGDETI-EGSSLFPGHVEAYEGAVKDGIHRTVHAGEVGSAEVV 224 Query: 822 QAMLDFCP-QRLGH-VCCLDDEE-WKKLKSSMIPVEICLTSNVMTGGTPSLELHHFADLY 992 + +D +R+GH ++DE + +L + E+C S+ +TG H Sbjct: 225 REAVDILKTERVGHGYHTIEDEALYNRLLKENMHFEVCPWSSYLTGAWNPKTTHAVVRFK 284 Query: 993 NAKHPLSICTDDSGLFSTSLSNEYYLVASTFGLSKAELFRLAQSAVEFVFADDEVKKSL 1169 + + S+ +DD +F +++ +Y +V G ++ E RL +A + F ++ KK L Sbjct: 285 DDQANYSLNSDDPLIFKSTVDTDYQMVKKDMGFTEEEFKRLNINAAKSSFLPEDEKKEL 343
>Q87TF3:ADD1_VIBPA Adenosine deaminase 1 - Vibrio parahaemolyticus| Length = 334 Score = 96.3 bits (238), Expect = 3e-19 Identities = 88/348 (25%), Positives = 149/348 (42%), Gaps = 9/348 (2%) Frame = +3 Query: 156 LPKVELHAHLNGSVRNSTLLELAKELGDKGVIVYEDVKDV-----IMKNDRSLPECFRLF 320 LP +LH HL+G++R T+LEL ++ G + D++ + I++ + SL Sbjct: 6 LPLTDLHRHLDGNIRTKTILELGQKFGI--ALPAYDIESLTPHVQIVEAEPSLVAFLSKL 63 Query: 321 DLFHILTTDHDTVTRIAKEVIGDFAAENVVYLEIRTTPKNNEAK-GMTKRSYMNAVVKGL 497 D + D D R+A E + D + Y E+R +P K + + AVV G+ Sbjct: 64 DWGVAVLGDLDACRRVAYENVEDALNAQIDYAELRFSPYYMAMKHKLPVAGVVEAVVDGV 123 Query: 498 KSVEDVDVVLNDEKISCAPMSDFGGDTKRKKIYVRLLLSIDRRETTSAALDTVNLALELK 677 + A M DFG I L+ + R T A ++ L K Sbjct: 124 Q----------------AGMRDFG-------IKANLIGIMSRTFGTDACQQELDAILSQK 160 Query: 678 DEGVIGIDLSGNPVVGEWETYLPALERAKELGIPTTIHCGEVPNRKEI-QAMLDFCPQRL 854 D ++ +DL+G+ + E ++ ++ ++ G+ T+H GE + + QA+ + R+ Sbjct: 161 DH-IVAVDLAGDELGQPGERFVSHFKQVRDAGLNVTVHAGEAAGAESMWQAIQELGATRI 219 Query: 855 GH--VCCLDDEEWKKLKSSMIPVEICLTSNVMTGGTPSLELHHFADLYNAKHPLSICTDD 1028 GH D + L + I +E CLTSN T SL H + + TDD Sbjct: 220 GHGVKAIHDPKLMDYLAENRIGIESCLTSNFQTSTVDSLANHPLKQFLDHGVLACLNTDD 279 Query: 1029 SGLFSTSLSNEYYLVASTFGLSKAELFRLAQSAVEFVFADDEVKKSLR 1172 + L EY + A GLS+ ++ + + +E F D K L+ Sbjct: 280 PAVEGIELPYEYEVAAPAAGLSQEQIRQAQINGLELAFISDAEKAELK 327
>P00813:ADA_HUMAN Adenosine deaminase - Homo sapiens (Human)| Length = 363 Score = 95.9 bits (237), Expect = 4e-19 Identities = 97/359 (27%), Positives = 163/359 (45%), Gaps = 22/359 (6%) Frame = +3 Query: 159 PKVELHAHLNGSVRNSTLLELAKELGDK-GVIVYEDVKDVI-MKNDRSLPECFRLFDLFH 332 PKVELH HL+GS++ T+L + G E + +VI M +LP+ FD + Sbjct: 10 PKVELHVHLDGSIKPETILYYGRRRGIALPANTAEGLLNVIGMDKPLTLPDFLAKFDYYM 69 Query: 333 -ILTTDHDTVTRIAKEVIGDFAAENVVYLEIRTTPKN-----------NEAKG-MTKRSY 473 + + + RIA E + A E VVY+E+R +P N+A+G +T Sbjct: 70 PAIAGCREAIKRIAYEFVEMKAKEGVVYVEVRYSPHLLANSKVEPIPWNQAEGDLTPDEV 129 Query: 474 MNAVVKGLKSVEDVDVVLNDEKISCAPMSDFGGDTKRKKIYVRLLLSIDRRETTSAALDT 653 + V +GL+ E DFG + R +L R + + Sbjct: 130 VALVGQGLQEGE----------------RDFG-------VKARSILCCMRHQPNWSP-KV 165 Query: 654 VNLALELKDEGVIGIDLSGNPVVGEWETYLP----ALERAKELGIPTTIHCGEVPNRKEI 821 V L + + + V+ IDL+G+ + + LP A + A + GI T+H GEV + + + Sbjct: 166 VELCKKYQQQTVVAIDLAGDETI-PGSSLLPGHVQAYQEAVKSGIHRTVHAGEVGSAEVV 224 Query: 822 QAMLDFCP-QRLGH-VCCLDDEE-WKKLKSSMIPVEICLTSNVMTGGTPSLELHHFADLY 992 + +D +RLGH L+D+ + +L+ + EIC S+ +TG H L Sbjct: 225 KEAVDILKTERLGHGYHTLEDQALYNRLRQENMHFEICPWSSYLTGAWKPDTEHAVIRLK 284 Query: 993 NAKHPLSICTDDSGLFSTSLSNEYYLVASTFGLSKAELFRLAQSAVEFVFADDEVKKSL 1169 N + S+ TDD +F ++L +Y + G ++ E RL +A + F ++ K+ L Sbjct: 285 NDQANYSLNTDDPLIFKSTLDTDYQMTKRDMGFTEEEFKRLNINAAKSSFLPEDEKREL 343
>P53984:ADD_STRVG Adenosine deaminase - Streptomyces virginiae| Length = 339 Score = 95.5 bits (236), Expect = 5e-19 Identities = 89/349 (25%), Positives = 151/349 (43%), Gaps = 5/349 (1%) Frame = +3 Query: 156 LPKVELHAHLNGSVRNSTLLELAKELGDK--GVIVYEDVKDVIMKNDRSLPECFRLFDLF 329 LPK LH H GS+R STLLELA + G + + + + ++R RL+D Sbjct: 10 LPKAHLHLHFTGSMRPSTLLELADKYGVRLPDALTAGEPPKLRATDERGWFRFQRLYDAA 69 Query: 330 HILTTDHDTVTRIAKEVIGDFAAENVVYLEIRTTPKNNEAKGMTKRSYMNAVVKGLKSVE 509 + D + R+ +E + + +LEI+ P SY ++ G+ + Sbjct: 70 RSCLREPDDIRRLVREAAEEDVRDGSGWLEIQVDPT----------SYA-PLLGGM--IP 116 Query: 510 DVDVVLNDEKISCAPMSDFGGDTKRKKIYVRLLLSIDRRETTSAALDTVNLALELKDEGV 689 V+++L + + A ++ + +R+L++ +R + A LA+ D G+ Sbjct: 117 AVEIIL--DAVDAA--------SRETGLGMRVLIAANRMKHPLDARTLARLAVRYADRGI 166 Query: 690 IGIDLSGNPVVGEWETYLPALERAKELGIPTTIHCGEVPNRKEIQAML-DFCPQRLGH-- 860 +G LS + G + A A+E G+ H GE+ ++ L D R+GH Sbjct: 167 VGFGLSNDERRGMARDFDRAFAIAREGGLLAAPHGGELTGPSSVRDCLDDLHASRIGHGV 226 Query: 861 VCCLDDEEWKKLKSSMIPVEICLTSNVMTGGTPSLELHHFADLYNAKHPLSICTDDSGLF 1040 D K+L I E+C SNV G E L+ A P+++ DD LF Sbjct: 227 RAAEDPRLLKRLADRQITCEVCPASNVALGVYERPEDVPLRTLFEAGVPMALGADDPLLF 286 Query: 1041 STSLSNEYYLVASTFGLSKAELFRLAQSAVEFVFADDEVKKSLRAAFEH 1187 + L+ +Y + + EL LA+ +V A D+V+ L A +H Sbjct: 287 GSRLAAQYEIARRHHAFTDTELAELARQSVRGSAAPDDVQAKLLAGIDH 335
>Q8X661:ADD_ECO57 Adenosine deaminase - Escherichia coli O157:H7| Length = 333 Score = 95.5 bits (236), Expect = 5e-19 Identities = 90/347 (25%), Positives = 149/347 (42%), Gaps = 8/347 (2%) Frame = +3 Query: 156 LPKVELHAHLNGSVRNSTLLELAKELGDKGVIVYEDVKDVI-----MKNDRSLPECFRLF 320 LP ++H HL+G++R T+LEL ++ + + ++ +I + N+ L Sbjct: 6 LPLTDIHRHLDGNIRPQTILELGRQYNIS--LPAQSLETLIPHVQVIANEPDLVSFLTKL 63 Query: 321 DLFHILTTDHDTVTRIAKEVIGDFAAENVVYLEIRTTPKNNEAKGMTKRSYMNAVVKGLK 500 D + D R+A E I D A + Y+E+R +P YM A+ L Sbjct: 64 DWGVKVLASLDACRRVAFENIEDAARNGLHYVELRFSP-----------GYM-AMAHQLP 111 Query: 501 SVEDVDVVLNDEKISCAPMSDFGGDTKRKKIYVRLLLSIDRRETTSAALDTVNLALELKD 680 V+ V++ + C FG K L+ I R AA A Sbjct: 112 VAGVVEAVIDGVREGCRT---FGVQAK--------LIGIMSRTFGEAACQQELEAFLAHR 160 Query: 681 EGVIGIDLSGNPVVGEWETYLPALERAKELGIPTTIHCGEVPNRKEI-QAMLDFCPQRLG 857 + + +DL+G+ + +L RA++ G T+H GE + I QA+ + +R+G Sbjct: 161 DQITALDLAGDELGFPGSLFLSHFNRARDAGWHITVHAGEAAGPESIWQAIRELGAERIG 220 Query: 858 H-VCCLDDEEWKK-LKSSMIPVEICLTSNVMTGGTPSLELHHFADLYNAKHPLSICTDDS 1031 H V ++D L I +E CLTSN+ T L H SI TDD Sbjct: 221 HGVKAIEDRALMDFLAEQQIGIESCLTSNIQTSTVAELAAHPLKTFLEHGIRASINTDDP 280 Query: 1032 GLFSTSLSNEYYLVASTFGLSKAELFRLAQSAVEFVFADDEVKKSLR 1172 G+ + +EY + A GLS+ ++ + + +E F + E K++LR Sbjct: 281 GVQGVDIIHEYTVAAPAAGLSREQIRQAQINGLEMAFLNAEEKRALR 327
>Q83RC0:ADD_SHIFL Adenosine deaminase - Shigella flexneri| Length = 333 Score = 95.1 bits (235), Expect = 6e-19 Identities = 90/347 (25%), Positives = 148/347 (42%), Gaps = 8/347 (2%) Frame = +3 Query: 156 LPKVELHAHLNGSVRNSTLLELAKELGDKGVIVYEDVKDVI-----MKNDRSLPECFRLF 320 LP ++H HL+G++R T+LEL ++ + + ++ +I + N+ L Sbjct: 6 LPLTDIHRHLDGNIRPQTILELGRQYNIS--LPAQSLETLIPHVQVIANEPDLVSFLTKL 63 Query: 321 DLFHILTTDHDTVTRIAKEVIGDFAAENVVYLEIRTTPKNNEAKGMTKRSYMNAVVKGLK 500 D + D R+A E I D A + Y+E+R +P YM A+ L Sbjct: 64 DWGVKVLASLDACRRVAFENIEDAARNGLRYVELRFSP-----------GYM-AMAHKLP 111 Query: 501 SVEDVDVVLNDEKISCAPMSDFGGDTKRKKIYVRLLLSIDRRETTSAALDTVNLALELKD 680 V+ V++ + C FG K L+ I R AA A Sbjct: 112 VAGVVEAVIDGVREGCRT---FGVQAK--------LIGIMSRTFGEAACQQELEAFLAHR 160 Query: 681 EGVIGIDLSGNPVVGEWETYLPALERAKELGIPTTIHCGEVPNRKEI-QAMLDFCPQRLG 857 + + +DL+G+ + +L RA++ G T+H GE + I QA+ + +R+G Sbjct: 161 DQITALDLAGDELGFPGSLFLSHFNRARDAGWHITVHAGEAAGPESIWQAIRELGAERIG 220 Query: 858 H-VCCLDDEEWKK-LKSSMIPVEICLTSNVMTGGTPSLELHHFADLYNAKHPLSICTDDS 1031 H V ++D L I +E CLTSN+ T L H SI TDD Sbjct: 221 HGVKAIEDRALMDFLAEQQIGIESCLTSNIQTSTVAELAAHPLKTFLEHGIRASINTDDP 280 Query: 1032 GLFSTSLSNEYYLVASTFGLSKAELFRLAQSAVEFVFADDEVKKSLR 1172 G+ + +EY + A GLS+ ++ + + +E F E K++LR Sbjct: 281 GVQGVDIIHEYTVAAPAAGLSREQIRQAQINGLEMAFLSAEEKRALR 327
>Q92T48:ADD_RHIME Adenosine deaminase - Rhizobium meliloti (Sinorhizobium meliloti)| Length = 324 Score = 95.1 bits (235), Expect = 6e-19 Identities = 79/344 (22%), Positives = 144/344 (41%), Gaps = 3/344 (0%) Frame = +3 Query: 156 LPKVELHAHLNGSVRNSTLLELAKELGDKGVIVYEDVKDVIMKNDRSLPECFRLFDLFHI 335 L K ELH H+ G+ L A++ G + D + + ++ S C+ D Sbjct: 5 LKKAELHCHIEGATPPELALRQARKYGVDTSAIIRD-RAYVWEDFTSFVRCY---DAVAS 60 Query: 336 LTTDHDTVTRIAKEVIGDFAAENVVYLEIRTTPKNNEAKGMTKRSYMNAVVKGLKSVEDV 515 L +A+ + + A +Y EI +P + G+ +Y+ + G+++ Sbjct: 61 LFRTEGDYALLAETYLTELAKAGTIYSEIIVSPDHGVTIGLGADAYIEGLAAGMEAAR-- 118 Query: 516 DVVLNDEKISCAPMSDFGGDTKRKKIYVRLLLSIDRRETTSAALDTVNLALELKDEGVIG 695 + I R+L++ R + + T A + V G Sbjct: 119 ---------------------VKTGIESRMLITGIRHLGPDSVIRTAEYAAMRRHPLVTG 157 Query: 696 IDLSGNPVVGEWETYLPALERAKELGIPTTIHCGEVPNRKEIQAMLDFC-PQRLGH-VCC 869 +L+G + + A + ++ G+ TIH GE+ ++ LD P R+ H V Sbjct: 158 FNLAGEERMHSVAEFSRAFDIVRDAGLGLTIHAGELSGAFSVRDALDHVRPARISHGVRA 217 Query: 870 LDDEEW-KKLKSSMIPVEICLTSNVMTGGTPSLELHHFADLYNAKHPLSICTDDSGLFST 1046 ++D + K+L + +E+C SNV P H LY A +++ +DD F T Sbjct: 218 IEDGDLVKRLADEGVVLEVCPGSNVALQVFPDFASHPLRRLYEAGVRVTLNSDDPPFFHT 277 Query: 1047 SLSNEYYLVASTFGLSKAELFRLAQSAVEFVFADDEVKKSLRAA 1178 SL+ EY + G S +E+ R+ ++A+E F D+ ++ L AA Sbjct: 278 SLAQEYEIAFHAMGFSDSEIDRMTKTAIEAAFVDEPTREKLLAA 321
>P22333:ADD_ECOLI Adenosine deaminase - Escherichia coli| Length = 333 Score = 95.1 bits (235), Expect = 6e-19 Identities = 90/347 (25%), Positives = 148/347 (42%), Gaps = 8/347 (2%) Frame = +3 Query: 156 LPKVELHAHLNGSVRNSTLLELAKELGDKGVIVYEDVKDVI-----MKNDRSLPECFRLF 320 LP ++H HL+G++R T+LEL ++ + + ++ +I + N+ L Sbjct: 6 LPLTDIHRHLDGNIRPQTILELGRQYNIS--LPAQSLETLIPHVQVIANEPDLVSFLTKL 63 Query: 321 DLFHILTTDHDTVTRIAKEVIGDFAAENVVYLEIRTTPKNNEAKGMTKRSYMNAVVKGLK 500 D + D R+A E I D A + Y+E+R +P YM A+ L Sbjct: 64 DWGVKVLASLDACRRVAFENIEDAARHGLHYVELRFSP-----------GYM-AMAHQLP 111 Query: 501 SVEDVDVVLNDEKISCAPMSDFGGDTKRKKIYVRLLLSIDRRETTSAALDTVNLALELKD 680 V+ V++ + C FG K L+ I R AA A Sbjct: 112 VAGVVEAVIDGVREGCRT---FGVQAK--------LIGIMSRTFGEAACQQELEAFLAHR 160 Query: 681 EGVIGIDLSGNPVVGEWETYLPALERAKELGIPTTIHCGEVPNRKEI-QAMLDFCPQRLG 857 + + +DL+G+ + +L RA++ G T+H GE + I QA+ + +R+G Sbjct: 161 DQITALDLAGDELGFPGSLFLSHFNRARDAGWHITVHAGEAAGPESIWQAIRELGAERIG 220 Query: 858 H-VCCLDDEEWKK-LKSSMIPVEICLTSNVMTGGTPSLELHHFADLYNAKHPLSICTDDS 1031 H V ++D L I +E CLTSN+ T L H SI TDD Sbjct: 221 HGVKAIEDRALMDFLAEQQIGIESCLTSNIQTSTVAELAAHPLKTFLEHGIRASINTDDP 280 Query: 1032 GLFSTSLSNEYYLVASTFGLSKAELFRLAQSAVEFVFADDEVKKSLR 1172 G+ + +EY + A GLS+ ++ + + +E F E K++LR Sbjct: 281 GVQGVDIIHEYTVAAPAAGLSREQIRQAQINGLEMAFLSAEEKRALR 327
>Q8FH99:ADD_ECOL6 Adenosine deaminase - Escherichia coli O6| Length = 333 Score = 95.1 bits (235), Expect = 6e-19 Identities = 90/347 (25%), Positives = 148/347 (42%), Gaps = 8/347 (2%) Frame = +3 Query: 156 LPKVELHAHLNGSVRNSTLLELAKELGDKGVIVYEDVKDVI-----MKNDRSLPECFRLF 320 LP ++H HL+G++R T+LEL ++ + + ++ +I + N+ L Sbjct: 6 LPLTDIHRHLDGNIRPQTILELGRQYNIS--LPAQSLETLIPHVQVIANEPDLVSFLTKL 63 Query: 321 DLFHILTTDHDTVTRIAKEVIGDFAAENVVYLEIRTTPKNNEAKGMTKRSYMNAVVKGLK 500 D + D R+A E I D A + Y+E+R +P YM A+ L Sbjct: 64 DWGVKVLASLDACRRVAFENIEDAARNGLHYVELRFSP-----------GYM-AMAHQLP 111 Query: 501 SVEDVDVVLNDEKISCAPMSDFGGDTKRKKIYVRLLLSIDRRETTSAALDTVNLALELKD 680 V+ V++ + C FG K L+ I R AA A Sbjct: 112 VAGVVEAVIDGVREGCRT---FGVQAK--------LIGIMSRTFGEAACQQELEAFLAHR 160 Query: 681 EGVIGIDLSGNPVVGEWETYLPALERAKELGIPTTIHCGEVPNRKEI-QAMLDFCPQRLG 857 + + +DL+G+ + +L RA++ G T+H GE + I QA+ + +R+G Sbjct: 161 DQITALDLAGDELGFPGSLFLSHFNRARDAGWHITVHAGEAAGPESIWQAIRELGAERIG 220 Query: 858 H-VCCLDDEEWKK-LKSSMIPVEICLTSNVMTGGTPSLELHHFADLYNAKHPLSICTDDS 1031 H V ++D L I +E CLTSN+ T L H SI TDD Sbjct: 221 HGVKAIEDRALMDFLAEQQIGIESCLTSNIQTSTVADLAAHPLKTFLEHGIRASINTDDP 280 Query: 1032 GLFSTSLSNEYYLVASTFGLSKAELFRLAQSAVEFVFADDEVKKSLR 1172 G+ + +EY + A GLS+ ++ + + +E F E K++LR Sbjct: 281 GVQGVDIIHEYTVAAPAAGLSREQIRQAQINGLEMAFLSAEEKRALR 327
>Q8ZPL9:ADD_SALTY Adenosine deaminase - Salmonella typhimurium| Length = 333 Score = 94.7 bits (234), Expect = 8e-19 Identities = 88/349 (25%), Positives = 154/349 (44%), Gaps = 8/349 (2%) Frame = +3 Query: 150 VALPKVELHAHLNGSVRNSTLLELAKELGDKGVIVYEDVKDVI-----MKNDRSLPECFR 314 + LP ++H HL+G++R T+L+L ++ + + ++ +I + L Sbjct: 4 ITLPLTDIHRHLDGNIRAQTILDLGRQFNI--ALPAQTLETLIPHVQVTSTEPDLVSFLT 61 Query: 315 LFDLFHILTTDHDTVTRIAKEVIGDFAAENVVYLEIRTTPKNNEAKGMTKRSYMNAVVKG 494 D + D R+A E I D A + Y+E+R +P YM A+ Sbjct: 62 KLDWGVKVLASLDACRRVAFENIEDAARNGLHYVELRFSP-----------GYM-AMAHQ 109 Query: 495 LKSVEDVDVVLNDEKISCAPMSDFGGDTKRKKIYVRLLLSIDRRETTSAALDTVNLALEL 674 L V+ V++ + C + FG + RL+ + R +A L ++ AL Sbjct: 110 LPIAGVVEAVIDGVRDGC---NTFG-------VEARLIGIMSRTFGEAACLQELD-ALLA 158 Query: 675 KDEGVIGIDLSGNPVVGEWETYLPALERAKELGIPTTIHCGEVPNRKEI-QAMLDFCPQR 851 E + +DL+G+ + +L RA++ G T+H GE + I QA+ + +R Sbjct: 159 HRENITALDLAGDELGFPGSLFLSHFNRARDAGWHITVHAGEAAGPESIWQAIRELGAER 218 Query: 852 LGH-VCCLDDEEWKK-LKSSMIPVEICLTSNVMTGGTPSLELHHFADLYNAKHPLSICTD 1025 +GH V ++D L I +E CLTSN+ T SL H S+ TD Sbjct: 219 IGHGVKAVEDRALMDFLAQQRIGIESCLTSNIQTSTVASLADHPLKTFLEHGVLASLNTD 278 Query: 1026 DSGLFSTSLSNEYYLVASTFGLSKAELFRLAQSAVEFVFADDEVKKSLR 1172 D + + +EY++ A GLS+ ++ + + +E F D K++LR Sbjct: 279 DPAVQGVDIIHEYHVAAPAAGLSREQIRQAQINGLEIAFLSDSEKRALR 327
>Q8Z6R2:ADD_SALTI Adenosine deaminase - Salmonella typhi| Length = 333 Score = 94.0 bits (232), Expect = 1e-18 Identities = 88/349 (25%), Positives = 154/349 (44%), Gaps = 8/349 (2%) Frame = +3 Query: 150 VALPKVELHAHLNGSVRNSTLLELAKELGDKGVIVYEDVKDVI-----MKNDRSLPECFR 314 + LP ++H HL+G++R T+L+L ++ + + ++ +I + L Sbjct: 4 ITLPLTDIHRHLDGNIRAQTILDLGRQFNI--ALPAQTLETLIPHVQVTSTEPDLVSFLT 61 Query: 315 LFDLFHILTTDHDTVTRIAKEVIGDFAAENVVYLEIRTTPKNNEAKGMTKRSYMNAVVKG 494 D + D R+A E I D A + Y+E+R +P YM A+ Sbjct: 62 KLDWGVKVLASLDACRRVAFENIEDAARNGLHYVELRFSP-----------GYM-AMAHQ 109 Query: 495 LKSVEDVDVVLNDEKISCAPMSDFGGDTKRKKIYVRLLLSIDRRETTSAALDTVNLALEL 674 L V+ V++ + C + FG + RL+ + R +A L ++ AL Sbjct: 110 LPIAGVVEAVIDGVRDGC---NTFG-------VEARLIGIMSRTFGEAACLQELD-ALLA 158 Query: 675 KDEGVIGIDLSGNPVVGEWETYLPALERAKELGIPTTIHCGEVPNRKEI-QAMLDFCPQR 851 E + +DL+G+ + +L RA++ G T+H GE + I QA+ + +R Sbjct: 159 HREKITALDLAGDELGFPGSLFLSHFNRARDAGWHITVHAGEAAGPESIWQAIRELGAER 218 Query: 852 LGH-VCCLDDEEWKK-LKSSMIPVEICLTSNVMTGGTPSLELHHFADLYNAKHPLSICTD 1025 +GH V ++D L I +E CLTSN+ T SL H S+ TD Sbjct: 219 IGHGVKAVEDRALMDFLAQQRIGIESCLTSNIQTSTVASLADHPLKTFLEHGVLASLNTD 278 Query: 1026 DSGLFSTSLSNEYYLVASTFGLSKAELFRLAQSAVEFVFADDEVKKSLR 1172 D + + +EY++ A GLS+ ++ + + +E F D K++LR Sbjct: 279 DPAVQGVDIIHEYHVAAPAAGLSREQIRQAQINGLEIAFLSDSEKRALR 327
>Q6GP70:ADA_XENLA Adenosine deaminase - Xenopus laevis (African clawed frog)| Length = 358 Score = 94.0 bits (232), Expect = 1e-18 Identities = 91/346 (26%), Positives = 156/346 (45%), Gaps = 9/346 (2%) Frame = +3 Query: 159 PKVELHAHLNGSVRNSTLLELAKELGDK--GVIVYEDVKDVIMKNDRSLPECFRLFDLF- 329 PKVELH HL+GS++ T++ AK+ K V ++ V K SL E + F+ + Sbjct: 9 PKVELHVHLDGSIKPETIIHFAKKRQIKLPADTVEGLLEHVSYKEPLSLTEFLQKFNHYM 68 Query: 330 HILTTDHDTVTRIAKEVIGDFAAENVVYLEIRTTPKNNEAKGMTKRSYMNAVVKGLKSVE 509 + D + + RIA E + A E V+Y+E+R +P S ++ + G K + Sbjct: 69 PAIAGDREAIKRIAYEFVEMKAKEGVIYVEVRYSPH------FLANSKVDPIPWGQKEGD 122 Query: 510 DVDVVLNDEKISCAPMSDFGGDTKRKKIYVRLLLSIDRRETTSAALDTVNLALELKDEGV 689 + DE + G+ K I R +L R + + + + L + +++ V Sbjct: 123 ----ITPDEVVDLVNQGLRKGE-KTFNIKARSILCC-MRHMPNWSSEVIELCKKYQNDTV 176 Query: 690 IGIDLSGNPVVG--EWETYLPALERAKELGIPTTIHCGEV-PNRKEIQAMLDFCPQRLGH 860 + IDL+G+ + + + A E A + GI T+H GEV P +A+ +R+GH Sbjct: 177 VAIDLAGDESLNCESYPGHRKAYEEAVKCGIHRTVHAGEVGPPSVVKEAVEVLKAERIGH 236 Query: 861 --VCCLDDEEWKKLKSSMIPVEICLTSNVMTGGT-PSLELHHFADLYNAKHPLSICTDDS 1031 D +K+L + + E+C S+ +T P H K S+ TDD Sbjct: 237 GYHTTEDPNLYKELLENNMHFEVCPWSSYLTSACHPDFTKHPATQFRKDKANFSLNTDDP 296 Query: 1032 GLFSTSLSNEYYLVASTFGLSKAELFRLAQSAVEFVFADDEVKKSL 1169 +F ++L +Y + G ++ E R+ +A + F D KK L Sbjct: 297 LIFGSTLDVDYSIAVQHMGFTEDEFKRVNINAAKSSFLPDNEKKEL 342
>Q9L0L6:ADD4_STRCO Probable adenosine deaminase 4 - Streptomyces coelicolor| Length = 343 Score = 90.1 bits (222), Expect = 2e-17 Identities = 88/356 (24%), Positives = 151/356 (42%), Gaps = 13/356 (3%) Frame = +3 Query: 156 LPKVELHAHLNGSVRNSTLLELAKELGDKGVIVYEDVKDVIMK---------NDRSLPEC 308 LPK LH H GS+R +TLLELA + GV + E + + + + ++R Sbjct: 10 LPKAHLHLHFTGSMRPTTLLELADK---HGVRLPETLTEALGRGESPKLRATDERGWFRF 66 Query: 309 FRLFDLFHILTTDHDTVTRIAKEVIGDFAAENVVYLEIRTTPKNNEAKGMTKRSYMNAVV 488 RL+D + + R+ +E + + +LEI+ P + + + ++ Sbjct: 67 QRLYDAARSCLQTPEDIQRLVREAAEEDLRDGSGWLEIQVDPTSYAPR-------LGGLI 119 Query: 489 KGLKSVED-VDVVLNDEKISCAPMSDFGGDTKRKKIYVRLLLSIDRRETTSAALDTVNLA 665 L+ + D V+ + D I +R+L++ +R + A LA Sbjct: 120 PALEIILDAVETTVRDTGIG-----------------MRVLVAANRMKHPLDARTLARLA 162 Query: 666 LELKDEGVIGIDLSGNPVVGEWETYLPALERAKELGIPTTIHCGEVPNRKEIQAMLDFCP 845 + + GV+G LS + G + A A++ G+ + H GE+ ++ LD Sbjct: 163 VRYAERGVVGFGLSNDERRGMARDFDRAFAIARDGGLLSAPHGGELTGPASVRDCLDDLE 222 Query: 846 -QRLGHV--CCLDDEEWKKLKSSMIPVEICLTSNVMTGGTPSLELHHFADLYNAKHPLSI 1016 R+GH D K+L + E+C SNV G E L+ A P+++ Sbjct: 223 ADRIGHGVRAAEDPRLLKRLADRQVTCEVCPASNVALGVYEKPEDVPLRRLFEAGVPMAL 282 Query: 1017 CTDDSGLFSTSLSNEYYLVASTFGLSKAELFRLAQSAVEFVFADDEVKKSLRAAFE 1184 DD LF + L+ +Y + G + AEL LA+ +V A +EVK L A + Sbjct: 283 GADDPLLFGSRLAAQYEIAREHHGFTDAELAELARQSVRGSAAPEEVKGKLLAGVD 338
>Q7N4H5:ADD_PHOLL Adenosine deaminase - Photorhabdus luminescens subsp. laumondii| Length = 333 Score = 89.0 bits (219), Expect = 4e-17 Identities = 85/350 (24%), Positives = 147/350 (42%), Gaps = 9/350 (2%) Frame = +3 Query: 150 VALPKVELHAHLNGSVRNSTLLELAKELGDKGVIVYEDVKDV-----IMKNDRSLPECFR 314 + LP +LH HL+G++R T+L+LA + + + D++ + I++N+ SL + Sbjct: 4 IKLPLTDLHRHLDGNIRPETILDLANQHNIQ--LPANDLESLLPHVQIIENEPSLVSFLQ 61 Query: 315 LFDLFHILTTDHDTVTRIAKEVIGDFAAENVVYLEIRTTPKNNEAKG-MTKRSYMNAVVK 491 D + D D RIA E + D + Y E+R +P + + A++ Sbjct: 62 KLDWGVAVLADLDACRRIAIENVEDAINTGLDYAELRFSPYYMAMNHKLPVEGVVEAIID 121 Query: 492 GLKSVEDVDVVLNDEKISCAPMSDFGGDTKRKKIYVRLLLSIDRRETTSAALDTVNLALE 671 G++S + I +RL+ + R A + +L Sbjct: 122 GIRSAR-----------------------QNNDIDIRLIGILSRTFGEQACTQELT-SLL 157 Query: 672 LKDEGVIGIDLSGNPVVGEWETYLPALERAKELGIPTTIHCGEVPNRKEI-QAMLDFCPQ 848 + + +DL+G+ + + +A++ G TIH GE + I QA+ + Sbjct: 158 AHQQHITALDLAGDELGFPGHLFQSHFTKARDAGWHITIHAGEAAGAESIWQAIRELGAT 217 Query: 849 RLGH--VCCLDDEEWKKLKSSMIPVEICLTSNVMTGGTPSLELHHFADLYNAKHPLSICT 1022 R+GH D L + I +E CLTSN+ T SL H SI T Sbjct: 218 RIGHGVKAITDPVLMDYLVENRIGIETCLTSNLQTSTVNSLLDHPLKQFLEKDILASINT 277 Query: 1023 DDSGLFSTSLSNEYYLVASTFGLSKAELFRLAQSAVEFVFADDEVKKSLR 1172 DD + + +EY + A GLS A++ + + +E F D K++LR Sbjct: 278 DDPAVEGIDIRHEYEIAAPAAGLSIAQIRQAQINGLETAFISDTEKQALR 327
>Q87GM3:ADD2_VIBPA Adenosine deaminase 2 - Vibrio parahaemolyticus| Length = 337 Score = 87.8 bits (216), Expect = 1e-16 Identities = 84/367 (22%), Positives = 156/367 (42%), Gaps = 13/367 (3%) Frame = +3 Query: 135 MRAWCVALPKVELHAHLNGSVRNSTLLELAKELGDKGVIVYEDVKDVIMKNDRSLPECFR 314 M A+ LPKVELH H+ GS+ + +LAK G D+ + L E ++ Sbjct: 1 MNAFIQGLPKVELHLHIEGSLEPELMFKLAKRNGI----------DIPYSSPSELREAYQ 50 Query: 315 LFDL----------FHILTTDHDTVTRIAKEVIGDFAAENVVYLEIRTTPKNNEAKGMTK 464 DL ++L T+ D + E + A+NV++ EI P+ + +G+ Sbjct: 51 FEDLQSFLDLYYQGANVLRTEQDFYD-LTWEYLEHCKADNVIHTEIFFDPQTHTERGIDF 109 Query: 465 RSYMNAVVKGLKSVEDVDVVLNDEKISCAPMSDFGGDTKRKKIYVRLLLSIDRRETTSAA 644 + +N + + L EK+ I +++ R + +A Sbjct: 110 DTVLNGISRALTD--------GREKLG---------------ITSQIIACFLRHLSEESA 146 Query: 645 LDTVNLALELKDEGVIGIDLSGNPVVGEWETYLPALERAKELGIPTTIHCGEVPNRKEIQ 824 ++T+ L+ +D+ +IG+ L + +L ++AKE G+ T H GE + I Sbjct: 147 METLQSVLKHRDK-IIGVGLDSSEKGHPPAKFLRVFQQAKEAGLLTVAHAGEEGPAQNIT 205 Query: 825 AMLDFCP-QRLGH-VCCLDDEEWK-KLKSSMIPVEICLTSNVMTGGTPSLELHHFADLYN 995 ++ R+ H V C++DE L + +P+ +C SN+ + H+ +L Sbjct: 206 DAIEMLEVSRVDHGVRCVEDEALVGSLIETKMPLTVCPLSNIKLCVFDEMGQHNIVELLR 265 Query: 996 AKHPLSICTDDSGLFSTSLSNEYYLVASTFGLSKAELFRLAQSAVEFVFADDEVKKSLRA 1175 ++I +DD F +++ + V + K EL + +A++ F D+E+K R Sbjct: 266 KGVAVTINSDDPVYFGGYMTDNFLAVNQAHPMIKEELAKFTLNAIDASFIDNELKAQYRH 325 Query: 1176 AFEHAAA 1196 E A Sbjct: 326 KVEQYVA 332
>Q8XXL5:ADD_RALSO Adenosine deaminase - Ralstonia solanacearum (Pseudomonas| solanacearum) Length = 345 Score = 78.6 bits (192), Expect = 6e-14 Identities = 85/348 (24%), Positives = 146/348 (41%), Gaps = 14/348 (4%) Frame = +3 Query: 159 PKVELHAHLNGSVRNSTLLELAKELGDKGVIVYEDVKDVIMKNDRSLPECFRLFDLFH-- 332 PK ELH H+ GS+ + LA+ G K + Y V +V + + + DL++ Sbjct: 15 PKAELHIHIEGSLEPELMFALAERNGVK--LPYASVDEV--RAAYAFNDLQSFLDLYYAG 70 Query: 333 --ILTTDHD----TVTRIAKEVIGDFAAENVVYLEIRTTPKNNEAKGMTKRSYMNAVVKG 494 +L T+ D T +A+ V A+NV + EI P+ + A+ + + +V+ Sbjct: 71 ASVLLTEQDFYDMTAAYVARAV-----ADNVRHAEIFFDPQTHTARDVPMHVVIGGIVRA 125 Query: 495 LKSVEDVDVVLNDEKISCAPMSDFGGDTKRKKIYVRLLLSIDRRETTSAALDTVNLALE- 671 L E + RL+L R + + A DT+ AL Sbjct: 126 LDDAE-----------------------RAHGFSSRLILCFLRHLSEADAFDTLEAALPY 162 Query: 672 LKDEG--VIGIDLSGNPVVGEWETYLPALERAKELGIPTTIHCGEV-PNRKEIQAMLDFC 842 ++D +IG+ L + E + R K LG+ H GE P + I A+ Sbjct: 163 IQDPANRIIGVGLDSSERGNPPEKFARVFARCKALGLRLVAHAGEEGPAQYVIDALDILQ 222 Query: 843 PQRLGH-VCCLDDEEW-KKLKSSMIPVEICLTSNVMTGGTPSLELHHFADLYNAKHPLSI 1016 +R+ H V +DD K+L +S + + +C SN P L H L +A +++ Sbjct: 223 VERIDHGVRAIDDAALVKRLAASRVALTVCPLSNEKLKVYPDLRDHSLKQLLDAGCAVTL 282 Query: 1017 CTDDSGLFSTSLSNEYYLVASTFGLSKAELFRLAQSAVEFVFADDEVK 1160 +DD F ++ + + GLS A+ LA+++ E F ++ K Sbjct: 283 HSDDPAYFGGYMNTNWLATFNALGLSAADAHTLARNSFEASFLPEQDK 330
>Q9A3M3:ADD_CAUCR Adenosine deaminase - Caulobacter crescentus (Caulobacter vibrioides)| Length = 344 Score = 78.2 bits (191), Expect = 8e-14 Identities = 86/370 (23%), Positives = 151/370 (40%), Gaps = 7/370 (1%) Frame = +3 Query: 108 TQTSEAEKEMRAWCVALPKVELHAHLNGSVRNSTLLELAKELGDKGVIVYEDVKDVIMKN 287 T S A + LPK ELH H+ GS+ + ELA+ G + + V+++ Sbjct: 2 TDASFAPSASAEFVRGLPKAELHMHIEGSLEPELMFELAQRNGI--TLPFASVEEIRAAY 59 Query: 288 DRSLPECFRLFDLFH----ILTTDHDTVTRIAKEVIGDFAAENVVYLEIRTTPKNNEAKG 455 D S + F D+++ +L T+ D +A AA+ + EI P+ + +G Sbjct: 60 DFSNLQDF--LDIYYQGAGVLITEAD-FKDLALAYFQRLAADGGAHAEIFFDPQTHTDRG 116 Query: 456 MTKRSYMNAVVKGLKSVEDVDVVLNDEKISCAPMSDFGGDTKRKKIYVRLLLSIDRRETT 635 + + MN ++ G+ E K + +L+L R + Sbjct: 117 IAFDTVMNGLLAGMDEAE-----------------------KTLGVTSKLILCFLRHLSE 153 Query: 636 SAALDTVNLALELKDEGVIGIDLSGNPVVGEWETYLPALERAKELGIPTTIHCGEVPNRK 815 AA +T+ A + + G+ L + V + L+ +++LG+ H GE Sbjct: 154 EAAFETLEQAKPWLAK-LAGVGLDSSEVGHPPAKFARVLQASRDLGLKVVAHAGEEGPPA 212 Query: 816 EIQAMLDFCP-QRLGHVC-CLDDEEWK-KLKSSMIPVEICLTSNVMTGGTPSLELHHFAD 986 + +D R+ H L+DE +L I + +C SN+ G PSL++H Sbjct: 213 YVWEAIDLVKVDRIDHGNRALEDEALTARLVKDGITLTVCPLSNLKLCGVPSLDVHPLKR 272 Query: 987 LYNAKHPLSICTDDSGLFSTSLSNEYYLVASTFGLSKAELFRLAQSAVEFVFADDEVKKS 1166 + + ++ +DD F L Y A GL++ ++ LA+++ F D K Sbjct: 273 MLDLGLKATVNSDDPAYFGGYLLENYLATADAVGLTRDDIVTLAKNSFAGSFLTDAEKAQ 332 Query: 1167 LRAAFEHAAA 1196 AA E AA Sbjct: 333 RIAAVEAYAA 342
>Q7WBG5:ADD_BORPA Adenosine deaminase - Bordetella parapertussis| Length = 317 Score = 73.6 bits (179), Expect = 2e-12 Identities = 84/343 (24%), Positives = 149/343 (43%), Gaps = 10/343 (2%) Frame = +3 Query: 135 MRAWCVALPKVELHAHLNGSVRNSTLLELAKELGDKGVIVYEDVKDVIMKNDRSLPECFR 314 M W ALPK ELH HL G++ + ELA+ G + + DV+ + D + F Sbjct: 1 MYDWLNALPKAELHLHLEGTLEPGLMFELARRNG--VALPWPDVESLRRAYDYDNLQEF- 57 Query: 315 LFDLFH----ILTTDHDTVTRIAKEVIGDFAAENVVYLEIRTTPKNNEAKGMTKRSYMNA 482 DL++ +L T+ D + + +NVV+ E P+ + +G+ + + Sbjct: 58 -LDLYYRGAEVLRTEQDFYD-LTWAYLLKCREQNVVHTEPFFDPQTHTDRGIAFETVLAG 115 Query: 483 VVKGLKSVEDVDVVLNDEKISCAPMSDFGGDTKRKKIYVRLLLSIDRRETTSAALDTVNL 662 + + L ED L + GG L+LS R AA+ T+ Sbjct: 116 ITQAL---EDGRTQLGIQ----------GG----------LILSFLRHLPEEAAMRTLEQ 152 Query: 663 ALELKDEGV-IGIDLS--GNPVVGEWETYLPALERAKELGIPTTIHCGEVPNRKEIQAML 833 AL +D + +G+D S G P + ERA+ G+P H GE + I L Sbjct: 153 ALPYRDAFIAVGLDSSERGFPP----RLFQRVFERARAAGLPAVAHAGEEGPPEYIWEAL 208 Query: 834 DFCP-QRLGH-VCCLDDEEW-KKLKSSMIPVEICLTSNVMTGGTPSLELHHFADLYNAKH 1004 D +R+ H V +DE ++L + IP+ +C SN S+ H+ +L Sbjct: 209 DLLQVRRIDHGVRAAEDERLIERLIDTQIPLTVCPLSNTRLRVFDSMAEHNILELLERGV 268 Query: 1005 PLSICTDDSGLFSTSLSNEYYLVASTFGLSKAELFRLAQSAVE 1133 +++ +DD F ++ ++ + G+++ + RLA ++++ Sbjct: 269 KVTVNSDDPAYFGGYITENFHALHEHLGMTQDQARRLAANSMD 311
>Q7WMY6:ADD_BORBR Adenosine deaminase - Bordetella bronchiseptica (Alcaligenes| bronchisepticus) Length = 317 Score = 73.6 bits (179), Expect = 2e-12 Identities = 84/343 (24%), Positives = 149/343 (43%), Gaps = 10/343 (2%) Frame = +3 Query: 135 MRAWCVALPKVELHAHLNGSVRNSTLLELAKELGDKGVIVYEDVKDVIMKNDRSLPECFR 314 M W ALPK ELH HL G++ + ELA+ G + + DV+ + D + F Sbjct: 1 MYDWLNALPKAELHLHLEGTLEPGLMFELARRNG--VALPWPDVESLRRAYDYDNLQEF- 57 Query: 315 LFDLFH----ILTTDHDTVTRIAKEVIGDFAAENVVYLEIRTTPKNNEAKGMTKRSYMNA 482 DL++ +L T+ D + + +NVV+ E P+ + +G+ + + Sbjct: 58 -LDLYYRGAEVLRTEQDFYD-LTWAYLLKCREQNVVHTEPFFDPQTHTDRGIAFETVLAG 115 Query: 483 VVKGLKSVEDVDVVLNDEKISCAPMSDFGGDTKRKKIYVRLLLSIDRRETTSAALDTVNL 662 + + L ED L + GG L+LS R AA+ T+ Sbjct: 116 ITQAL---EDGRTQLGIQ----------GG----------LILSFLRHLPEEAAMRTLEQ 152 Query: 663 ALELKDEGV-IGIDLS--GNPVVGEWETYLPALERAKELGIPTTIHCGEVPNRKEIQAML 833 AL +D + +G+D S G P + ERA+ G+P H GE + I L Sbjct: 153 ALPYRDAFIAVGLDSSERGFPP----RLFQRVFERARAAGLPAVAHAGEEGPPEYIWEAL 208 Query: 834 DFCP-QRLGH-VCCLDDEEW-KKLKSSMIPVEICLTSNVMTGGTPSLELHHFADLYNAKH 1004 D +R+ H V +DE ++L + IP+ +C SN S+ H+ +L Sbjct: 209 DLLQVRRIDHGVRAAEDERLIERLIDTQIPLTVCPLSNTRLRVFDSMAEHNILELLERGV 268 Query: 1005 PLSICTDDSGLFSTSLSNEYYLVASTFGLSKAELFRLAQSAVE 1133 +++ +DD F ++ ++ + G+++ + RLA ++++ Sbjct: 269 KVTVNSDDPAYFGGYITENFHALHEHLGMTQDQARRLAANSMD 311
>Q88QA3:ADD_PSEPK Adenosine deaminase - Pseudomonas putida (strain KT2440)| Length = 315 Score = 72.8 bits (177), Expect = 3e-12 Identities = 77/343 (22%), Positives = 147/343 (42%), Gaps = 10/343 (2%) Frame = +3 Query: 135 MRAWCVALPKVELHAHLNGSVRNSTLLELAKELGDKGVIVYEDVKDVIMKNDRSLPECFR 314 M W ALPK ELH HL GS+ L LA+ +K + + DV+ ++ + Sbjct: 1 MYDWLNALPKAELHLHLEGSLEPELLFALAER--NKIALPWADVET--LRGAYAFNNLQE 56 Query: 315 LFDLFH----ILTTDHDTVTRIAKEVIGDFAAENVVYLEIRTTPKNNEAKGMTKRSYMNA 482 DL++ +L T+ D + + A+NV++ E P+ + +G+ +N Sbjct: 57 FLDLYYQGADVLRTEQDFYD-LTWAYLQRCKAQNVIHTEPFFDPQTHTDRGIAFEVVLNG 115 Query: 483 VVKGLKSVEDVDVVLNDEKISCAPMSDFGGDTKRKKIYVRLLLSIDRRETTSAALDTVNL 662 + + LK + + I L+LS R + A T++ Sbjct: 116 ISQALKDGRE-----------------------QLGISSGLILSFLRHLSEDEAQKTLDQ 152 Query: 663 ALELKDEGV-IGIDLS--GNPVVGEWETYLPALERAKELGIPTTIHCGEVPNRKEIQAML 833 AL +D + +G+D S G+P + +RA+ G H GE + I L Sbjct: 153 ALPFRDAFIAVGLDSSEMGHPP----SKFQRVFDRARSEGFVAVAHAGEEGPPEYIWEAL 208 Query: 834 DFCP-QRLGH-VCCLDDEE-WKKLKSSMIPVEICLTSNVMTGGTPSLELHHFADLYNAKH 1004 D +R+ H V ++DE +++ IP+ +C SN + H+ D+ Sbjct: 209 DLLKIKRIDHGVRAIEDERLMQRIIDEQIPLTVCPLSNTKLCVFDHMSQHNILDMLERGV 268 Query: 1005 PLSICTDDSGLFSTSLSNEYYLVASTFGLSKAELFRLAQSAVE 1133 +++ +DD F ++ ++ + + G+++ + RLAQ++++ Sbjct: 269 KVTVNSDDPAYFGGYVTENFHALHTHLGMTEDQARRLAQNSLD 311
>Q9I6Y4:ADD_PSEAE Adenosine deaminase - Pseudomonas aeruginosa| Length = 316 Score = 72.4 bits (176), Expect = 4e-12 Identities = 78/340 (22%), Positives = 145/340 (42%), Gaps = 7/340 (2%) Frame = +3 Query: 135 MRAWCVALPKVELHAHLNGSVRNSTLLELAKELGDKGVIVYEDVKDVIMKNDRSLPECFR 314 M W ALPK ELH HL G++ L LA+ ++ + + DV+ ++ + Sbjct: 1 MYEWLNALPKAELHLHLEGTLEPELLFALAER--NRIALPWNDVET--LRKAYAFNNLQE 56 Query: 315 LFDLFH----ILTTDHDTVTRIAKEVIGDFAAENVVYLEIRTTPKNNEAKGMTKRSYMNA 482 DL++ +L T+ D + + A+NVV++E P+ + +G+ Sbjct: 57 FLDLYYAGADVLRTEQDFYD-LTWAYLQKCKAQNVVHVEPFFDPQTHTDRGIP----FEV 111 Query: 483 VVKGLKSVEDVDVVLNDEKISCAPMSDFGGDTKRKKIYVRLLLSIDRRETTSAALDTVNL 662 V+ G+++ L D + K I L+LS R + A T++ Sbjct: 112 VLAGIRAA------LRDGE-------------KLLGIRHGLILSFLRHLSEEQAQKTLDQ 152 Query: 663 ALELKDEGVIGIDLSGNPVVGEWETYLPALERAKELGIPTTIHCGEVPNRKEIQAMLDFC 842 AL +D I + L + V + +RA+ G T H GE + I LD Sbjct: 153 ALPFRD-AFIAVGLDSSEVGHPPSKFQRVFDRARSEGFLTVAHAGEEGPPEYIWEALDLL 211 Query: 843 P-QRLGH-VCCLDDEE-WKKLKSSMIPVEICLTSNVMTGGTPSLELHHFADLYNAKHPLS 1013 +R+ H V +DE ++L IP+ +C SN + H D+ ++ Sbjct: 212 KVERIDHGVRAFEDERLMRRLIDEQIPLTVCPLSNTKLCVFDDMSQHTILDMLERGVKVT 271 Query: 1014 ICTDDSGLFSTSLSNEYYLVASTFGLSKAELFRLAQSAVE 1133 + +DD F ++ ++ + + G+++ + RLAQ++++ Sbjct: 272 VNSDDPAYFGGYVTENFHALQQSLGMTEEQARRLAQNSLD 311
>Q6CM42:ADA_KLULA Adenosine deaminase - Kluyveromyces lactis (Yeast) (Candida| sphaerica) Length = 355 Score = 71.6 bits (174), Expect = 7e-12 Identities = 90/364 (24%), Positives = 147/364 (40%), Gaps = 14/364 (3%) Frame = +3 Query: 120 EAEKEMRAWCVALPKVELHAHLNGSVRNSTLLELAKELGDKGVIVYEDVKD---VIMKND 290 E E+ + LPK E H HL G++ L +L + G + + + VI N Sbjct: 5 ECTDEVTNFLTELPKCEHHLHLEGTLEPELLFQLVERNGVQLPGTFPKTVNELHVIYNNF 64 Query: 291 RSLPECFRLFDLFHILTTDHDTVTRIAKEVIGDFAAENVVYLEIRTTPKNNEAKGMTKRS 470 L + + + + D +A + + + + E+ P+++ ++G++ Sbjct: 65 ADLQDFLNYYYIGCNVLLSEDDFFELAWSYFKRVSTQGLRHAEVFYDPQSHTSRGIS--- 121 Query: 471 YMNAVVKGLKSVEDVDVVLNDEKISCAPMSDFGGDTKRKKIYVRLLLSIDRRETTSAALD 650 + V KG E+ +F TK L++ + R +D Sbjct: 122 -LEVVTKGF------------ERACAKAQEEFNISTK-------LIMCLLRHCPVEECMD 161 Query: 651 TVNLALELKDEGVI---GIDLSGNPVVGEW--ETYLPALERAKELGIPTTIHCGEVPNRK 815 TV A L + GVI G+D S P E E Y A KEL + T H GE + Sbjct: 162 TVKSAKSLIESGVIDGLGLDSSERPFPPELFVECYQLAKSYNKELQL--TAHAGEEGDPS 219 Query: 816 EIQAMLDFCPQ-RLGH-VCCLDDEEW-KKLKSSMIPVEICLTSNV---MTGGTPSLELHH 977 + LD R+ H V ++D E K+L + + + +C SNV + L L Sbjct: 220 FVTNTLDLLETTRIDHGVRSIEDAELIKRLAAQKVMLTLCPLSNVKLQVVKDVSELPLQE 279 Query: 978 FADLYNAKHPLSICTDDSGLFSTSLSNEYYLVASTFGLSKAELFRLAQSAVEFVFADDEV 1157 F D P SI +DD F + Y V S FG SKA ++A+ ++E + D + Sbjct: 280 FLD---NDVPFSINSDDPAYFGGYILQNYLEVYSRFGWSKAVWAKIARQSIEGSWCDPKR 336 Query: 1158 KKSL 1169 K+ L Sbjct: 337 KQEL 340
>Q889J2:ADD_PSESM Adenosine deaminase - Pseudomonas syringae pv. tomato| Length = 317 Score = 70.5 bits (171), Expect = 2e-11 Identities = 79/343 (23%), Positives = 147/343 (42%), Gaps = 10/343 (2%) Frame = +3 Query: 135 MRAWCVALPKVELHAHLNGSVRNSTLLELAKELGDKGVIVYEDVKDVIMKNDRSLPECFR 314 M W ALPK ELH HL GS+ L LA+ ++ + + DV+ ++ + Sbjct: 1 MYDWLNALPKAELHLHLEGSLEPELLFALAER--NRIALPWNDVE--ALRKAYAFNNLQE 56 Query: 315 LFDLFH----ILTTDHDTVTRIAKEVIGDFAAENVVYLEIRTTPKNNEAKGMTKRSYMNA 482 DL++ +L T+ D + + +NV++ E P+ + +G+ + Sbjct: 57 FLDLYYRGADVLRTEQDFYD-LTWAYLLRCKEQNVIHTEPFFDPQTHTDRGIAFEVVLAG 115 Query: 483 VVKGLKSVEDVDVVLNDEKISCAPMSDFGGDTKRKKIYVRLLLSIDRRETTSAALDTVNL 662 + LK + S G D+ L+LS R + A T++ Sbjct: 116 ITGALKDGK----------------SKLGVDSG-------LILSFLRHLSEDEAEKTLDQ 152 Query: 663 ALELKDEGV-IGIDLS--GNPVVGEWETYLPALERAKELGIPTTIHCGEVPNRKEIQAML 833 AL +D V +G+D S G+P + +RA+ G T H GE + I L Sbjct: 153 ALPFRDAFVAVGLDSSEMGHPP----SKFQRVFDRARNEGFLTVAHAGEEGPPEYIWEAL 208 Query: 834 DFCP-QRLGH-VCCLDDEE-WKKLKSSMIPVEICLTSNVMTGGTPSLELHHFADLYNAKH 1004 D QR+ H V ++DE +++ IP+ +C SN + H+ D+ Sbjct: 209 DLLKIQRIDHGVRAIEDERLMQRIIDEQIPLTVCPLSNTKLCVFDDMAQHNILDMLERGV 268 Query: 1005 PLSICTDDSGLFSTSLSNEYYLVASTFGLSKAELFRLAQSAVE 1133 +++ +DD F ++ ++ + + G+++ + RLAQ++++ Sbjct: 269 KVTVNSDDPAYFGGYVTENFHALHTHLGMTEDQARRLAQNSLD 311
>Q7M9R5:ADD_WOLSU Adenosine deaminase - Wolinella succinogenes| Length = 331 Score = 69.7 bits (169), Expect = 3e-11 Identities = 75/344 (21%), Positives = 145/344 (42%), Gaps = 9/344 (2%) Frame = +3 Query: 156 LPKVELHAHLNGSVRNSTLLELAKELGDKGVIVYEDVKDVIMKNDRSLPECFRLFDLFH- 332 LPK ELH H+ GS+ + ELA++ ++ + Y+ V++V + S D+++ Sbjct: 11 LPKAELHLHIEGSLEPELMFELAQK--NRIPLPYKSVEEV--RKAYSFTSLQSFLDIYYA 66 Query: 333 ---ILTTDHDTVTRIAKEVIGDFAAENVVYLEIRTTPKNNEAKGMTKRSYMNAVVKGLKS 503 +L T+ D +A + A+N+ + EI P+ + ++G++ + + + K L+ Sbjct: 67 GAKVLLTESDFFD-LAWAYLLRCKAQNICHTEIFFDPQTHTSRGVSFETVIEGITKALEK 125 Query: 504 VEDVDVVLNDEKISCAPMSDFGGDTKRKKIYVRLLLSIDRRETTSAALDTVNLALELKDE 683 E K I L++ R + S + + +L +++ Sbjct: 126 GE-----------------------KELGISSFLIMCFLRHLSESEGFEILKSSLPFREK 162 Query: 684 GVIGIDLSGNPVVGEWETYLPALERAKELGIPTTIHCGEVPNRKEI-QAMLDFCPQRLGH 860 ++G+ L + V + ++ G H GE + I +A+ +R+ H Sbjct: 163 -ILGVGLDSSEVGHPPSKFERLFLECRKAGYKIVAHAGEEGDSSYIWEAIHKLQVERIDH 221 Query: 861 -VCCLDDE---EWKKLKSSMIPVEICLTSNVMTGGTPSLELHHFADLYNAKHPLSICTDD 1028 + C +DE EW L P+ +C SNV +L H+ L +++ +DD Sbjct: 222 GIRCEEDENLVEW--LIQKQTPLTVCPLSNVKLQAVKNLSEHNILRLLRKGVLVTVNSDD 279 Query: 1029 SGLFSTSLSNEYYLVASTFGLSKAELFRLAQSAVEFVFADDEVK 1160 F L+ Y ++ SK EL LA ++ + F +E K Sbjct: 280 PAYFGGYLNENYEALSEHLNASKEELKALAINSFKASFLSEEKK 323
>Q4IMJ1:ADA_GIBZE Adenosine deaminase - Gibberella zeae (Fusarium graminearum)| Length = 353 Score = 68.2 bits (165), Expect = 8e-11 Identities = 90/364 (24%), Positives = 144/364 (39%), Gaps = 11/364 (3%) Frame = +3 Query: 126 EKEMRAWCVALPKVELHAHLNGSVRNSTLLELAKELGDK--GVIVYEDVKDVIMKNDR-- 293 + + ++ ALPKVE H H+ G++ L LA++ G + VYE + + R Sbjct: 3 KSRVHSFLQALPKVEQHLHIEGTLEPELLFTLAEKNGIELPNDPVYESADKLRERYGRFT 62 Query: 294 SLPECFRLFDL-FHILTTDHDTVTRIAKEVIGDFAAENVVYLEIRTTPKNNEAKGMTKRS 470 SL + + L +L T++D T +A + A ENV + EI P+ + A+G++ Sbjct: 63 SLDDFLHYYYLGMSVLITENDFET-LAYQYFQRAAGENVRHAEIFFDPQAHIARGVS--- 118 Query: 471 YMNAVVKGLKSVEDVDVVLNDEKISCAPMSDFGGDTKRKKIYVRLLLSIDRR---ETTSA 641 + VV GL + + K I V L++ I R + A Sbjct: 119 -YDTVVAGLVAAKH-------------------RAQKELGITVELIVCILRHLPVPESHA 158 Query: 642 ALDTVNLALELKDEGVIGIDLSGNPVVGEWETYLPALERAKELGIPTTIHCGEVPNRKEI 821 +DT+ D + G + + E + R + G T H GE I Sbjct: 159 LVDTLLDRGHFNDGTLTGFGMVSSEKAFPPELFTDVYARVAKTGTHLTTHAGEEAPPSFI 218 Query: 822 QAMLDFCP-QRLGH--VCCLDDEEWKKLKSSMIPVEICLTSNVMTGGTPSLELHHFADLY 992 A L+ R+ H D E KKL ++ + C SNV P L + Sbjct: 219 TASLEHLKVSRIDHGLAAAQDPELLKKLAANRTLLTFCPWSNVALCNLPELADAPVREFL 278 Query: 993 NAKHPLSICTDDSGLFSTSLSNEYYLVASTFGLSKAELFRLAQSAVEFVFADDEVKKSLR 1172 +A S+ +DD F + Y V TF LS + + + AVE + +E KK + Sbjct: 279 DAGVLFSVNSDDPAYFGAYVQEVYCRVQDTFNLSVKDWAWIVRGAVEESWCSEERKKEIL 338 Query: 1173 AAFE 1184 E Sbjct: 339 KEME 342
>Q9RDE5:ADD3_STRCO Probable adenosine deaminase 3 - Streptomyces coelicolor| Length = 340 Score = 65.9 bits (159), Expect = 4e-10 Identities = 87/351 (24%), Positives = 149/351 (42%), Gaps = 9/351 (2%) Frame = +3 Query: 156 LPKVELHAHLNGSVRNSTLLELAKELGDKGVIVYEDVKDVIMKNDR--SLPECFRLF-DL 326 LPK ELH H+ G++ LA G + Y D +D + + R L L+ +L Sbjct: 11 LPKAELHLHIEGTLEPELAFALAARNGVS--LPYAD-EDALREAYRFADLQSFLNLYYEL 67 Query: 327 FHILTTDHDTVTRIAKEVIGDFAAENVVYLEIRTTPKNNEAKGMTKRSYMNAVVKGLKSV 506 +L T+ D +A + AA+ V + EI P+ + A+G+ M VV+GL Sbjct: 68 MAVLRTERD-FEDLADAYLARAAAQGVRHAEIFFDPQAHLARGVE----MGTVVEGLWRA 122 Query: 507 EDVDVVLNDEKISCAPMSDFGGDTKRKKIYVRLLLSIDRRETTSAALDTVNLALELKDEG 686 G + + RL+L R E+ +A+ T++ A D Sbjct: 123 -------------------LGASRENHGVSTRLILCFLRDESAESAMRTLDAAGPYLDRI 163 Query: 687 V-IGIDLS--GNPVVGEWETYLPALERAKELGIPTTIHCGEV-PNRKEIQAMLDFCPQRL 854 +G+D + G+P V E Y E A LG+ H GE P ++A+ +R+ Sbjct: 164 TGVGLDSAEVGHPPVKFREVY----EAAAALGLRRVAHAGEEGPPAYVVEALDVLGVERI 219 Query: 855 GH-VCCLDDEEW-KKLKSSMIPVEICLTSNVMTGGTPSLELHHFADLYNAKHPLSICTDD 1028 H + ++D ++L +P+ +C SNV +L H + +A ++ +DD Sbjct: 220 DHGLRSVEDPALVERLVRERVPLTLCPLSNVRLRTVDTLADHPLPAMLDAGLMCTVNSDD 279 Query: 1029 SGLFSTSLSNEYYLVASTFGLSKAELFRLAQSAVEFVFADDEVKKSLRAAF 1181 F + + V GL+ L LA+++ F +D+ + LRA + Sbjct: 280 PAYFGGYAGDNFDAVRQALGLTGERLRELARNSFLASFLEDD--EELRARY 328
>Q8X1T6:ADA_EMENI Adenosine deaminase - Emericella nidulans (Aspergillus nidulans)| Length = 364 Score = 63.2 bits (152), Expect = 3e-09 Identities = 75/357 (21%), Positives = 136/357 (38%), Gaps = 9/357 (2%) Frame = +3 Query: 126 EKEMRAWCVALPKVELHAHLNGSVRNSTLLELAKELG-----DKGVIVYEDVKDVIMKND 290 + + A+ +LPK E H HL G + + +A++ Y V+ + + Sbjct: 9 QSQWHAFLHSLPKCEHHVHLEGCLEPPLIFSMARKNNVSLPSPSSNPAYTSVETLSKRYG 68 Query: 291 R--SLPECFRLFDLFHILTTDHDTVTRIAKEVIGDFAAENVVYLEIRTTPKNNEAKGMTK 464 SL + + + + +A AE V + E+ P+ + +G+ Sbjct: 69 HFSSLDDFLSFYFIGMTVLKTQSDFAELAWTYFKRAHAEGVHHTEVFFDPQVHMERGLEY 128 Query: 465 RSYMNAVVKGLKSVEDVDVVLNDEKISCAPMSDFGGDTKRKKIYVRLLLSIDRRETTSAA 644 R ++ V G K E + G T+ +++ L + A Sbjct: 129 RVIVDGYVDGCKRAE----------------KELGISTRLIMCFLKHLPLESAQRLYDTA 172 Query: 645 LDTVNLALELKDEGVIGIDLSGNPVVGEWETYLPALERAKELGIPTTIHCGEVPNRKEIQ 824 L+ +L L+ ++ + G+ S + V + + P AKE I T H GE + I Sbjct: 173 LNEGDLGLDGRNPVIHGLGASSSEVGPPKDLFRPIYLGAKEKSINLTAHAGEEGDASYIA 232 Query: 825 AMLDFCPQRLGHVCCL--DDEEWKKLKSSMIPVEICLTSNVMTGGTPSLELHHFADLYNA 998 A LD R+ H L D E +++ + + +C SN+ S+ +A Sbjct: 233 AALDMGATRIDHGIRLGEDPELMERVAREEVLLTVCPVSNLQLKCVKSVAEVPIRKFLDA 292 Query: 999 KHPLSICTDDSGLFSTSLSNEYYLVASTFGLSKAELFRLAQSAVEFVFADDEVKKSL 1169 SI +DD F + Y V F LS A+ +A++ V+ + +E K L Sbjct: 293 GVRFSINSDDPAYFGAYILECYCAVQEAFNLSVADWRLIAENGVKGSWIGEERKNEL 349
>Q9P6I7:ADA_SCHPO Adenosine deaminase - Schizosaccharomyces pombe (Fission yeast)| Length = 367 Score = 61.6 bits (148), Expect = 7e-09 Identities = 79/353 (22%), Positives = 138/353 (39%), Gaps = 10/353 (2%) Frame = +3 Query: 156 LPKVELHAHLNGSVRNSTLLELAKELG-----DKGVIVYEDVKDVIMKNDRSLPECFRLF 320 LPK E H HL G + + LAK+ G D ++ L + R + Sbjct: 13 LPKCEHHVHLEGCLSPDLVFRLAKKNGITLPSDDAAYTTPSTLLASYEHFGCLDDFLRYY 72 Query: 321 DLFHILTTDHDTVTRIAKEVIGDFAAENVVYLEIRTTPKNNEAKGMTKRSYMNAVVKGLK 500 + + + +A E ++ V + E+ P+ + ++G++ Sbjct: 73 YIAVSVLIEASDFEALAYEYFSIAHSQGVHHAEVFFDPQTHTSRGIS------------- 119 Query: 501 SVEDVDVVLNDEKISCAPMS-DFGGDTKRKKIYVRLLLSIDRRETTSAALDTVNLALELK 677 DVV++ +C + DFG T ++R L S ET + AL + Sbjct: 120 ----YDVVVSGFSAACERANRDFGMSTNLIMCFLRHLPSEAAHETFAEALKRNDF----- 170 Query: 678 DEGVI-GIDLSGNPVVGEWETYLPALERAKELGIPTTIHCGEVPNRKEIQAMLD-FCPQR 851 + G++ G+ L + V E + + A E GI T H GE + I++ LD QR Sbjct: 171 ENGIVAGVGLDSSEVDFPPELFQEVYKLAAEKGIRRTGHAGEEGDPSYIRSGLDNLSLQR 230 Query: 852 LGHVCCL--DDEEWKKLKSSMIPVEICLTSNVMTGGTPSLELHHFADLYNAKHPLSICTD 1025 + H L D E K++ I + +C SN+ S+ + A P SI D Sbjct: 231 IDHGIRLVEDKELMKRVAEENIMLTMCPLSNLKLRCVNSIAELPVREFLEAGVPFSINCD 290 Query: 1026 DSGLFSTSLSNEYYLVASTFGLSKAELFRLAQSAVEFVFADDEVKKSLRAAFE 1184 D F Y+ + F L+ E +A +A+ + + K+ L ++ + Sbjct: 291 DPAYFGGYTLENYFAIQKHFNLTVKEWVFIANAAINGSWISGKRKEELLSSVQ 343
>P58781:CECR1_DANRE Cat eye syndrome critical region protein 1 homolog precursor - Danio| rerio (Zebrafish) (Brachydanio rerio) Length = 503 Score = 59.3 bits (142), Expect = 4e-08 Identities = 66/269 (24%), Positives = 109/269 (40%), Gaps = 17/269 (6%) Frame = +3 Query: 375 EVIGDFAAENVVYLEIRTTPKNNEAKGMTKRSYMNAVVKGLKSVEDVDVVLNDEKISCAP 554 E + F +N++Y+EIR L ++D LND+ S A Sbjct: 223 EGLRQFYEDNIMYVEIRAL---------------------LPQTYELDGRLNDKDWSMAA 261 Query: 555 MSDFGGDTKRKK---IYVRLLLSIDRRETTSAALDTVNLALELK---DEGVIGIDLSGNP 716 + K+ I R++ ++ R+ + A+ TV A+ L+ + + G D G Sbjct: 262 CQEVVNQFKKHHPDFIGARVIFTVHRKINATEAVKTVEEAMILRRNFPDVMAGFDFVGQE 321 Query: 717 VVGEWETYLP---ALERAKELGIPTTIHCGEVPNR-----KEIQAMLDFCPQRLGHVCCL 872 +G Y +L K +P H GE ++ + + L F R+GH L Sbjct: 322 DLGRPLWYFKDALSLPEDKGFNLPYFFHAGETDSQGTDVDQNLMDALLFNTTRIGHGFAL 381 Query: 873 DDEEWKK--LKSSMIPVEICLTSNVMTGGTPSLELHHFADLYNAKHPLSICTDDSGLF-S 1043 K + +P+E+C SN + L H A L HPL I +DD +F + Sbjct: 382 ARHPVVKEMARKMYVPIEVCPISNQVLKLVSDLRDHPAAVLMAEGHPLVISSDDPAVFGA 441 Query: 1044 TSLSNEYYLVASTFGLSKAELFRLAQSAV 1130 T+LS+++Y FG L L + A+ Sbjct: 442 TALSHDFYEAFMGFGGMSFNLGTLKELAL 470
>Q59ZB1:ADA_CANAL Adenosine deaminase - Candida albicans (Yeast)| Length = 356 Score = 57.8 bits (138), Expect = 1e-07 Identities = 81/370 (21%), Positives = 147/370 (39%), Gaps = 15/370 (4%) Frame = +3 Query: 120 EAEKEMRAWCVALPKVELHAHLNGSVRNSTLLELAKELGDKGVIVYEDVKDVIMK-NDR- 293 E + M + LPK E H HL G++ S L +LAK + + E + + NDR Sbjct: 5 ECSEHMENFLRELPKCEHHVHLEGTLEPSLLFKLAKR---NNITLPETFPKTVEECNDRY 61 Query: 294 -SLPECFRLFDLFHI----LTTDHDTVTRIAKEVIGDFAAENVVYLEIRTTPKNNEAKGM 458 + D ++I L T++D +A + ++ ++ E+ P+ + + + Sbjct: 62 NRFADLQDFLDHYYIGMGVLITENDFYD-LAMDYFTKAHSDGCLHSEVFFDPQGHVERNI 120 Query: 459 TKRSYMNAVVKGLKSVEDVDVVLNDEKISCAPMSDFGGDTKRKKIYVRLLLSIDRRETTS 638 D+DVV+ +C + G T + L++ + R Sbjct: 121 -----------------DIDVVVQGFNRACKDANTKYGTTNK------LIMCLLRHLPAE 157 Query: 639 AALDTVNLALELKDEGVI---GIDLSGNPVVGEW--ETYLPALERAKELGIPTTIHCGEV 803 L T++ A + +G+I G+D S P E Y + E+G+ T H GE Sbjct: 158 NGLQTIHSASKYYQDGIIHGLGLDSSEKPFPPNLFTECYAHIKDNFPEVGL--TAHAGEE 215 Query: 804 PNRKEIQAMLDFCP-QRLGH-VCCLDDEE-WKKLKSSMIPVEICLTSNVMTGGTPSLELH 974 + + L+ R+ H V EE ++L + +C SNV ++ Sbjct: 216 GDHTFVSDALNLLKVSRIDHGVNSHQSEELMQRLAEQKTLLSLCPLSNVKLQVVKDVKEL 275 Query: 975 HFADLYNAKHPLSICTDDSGLFSTSLSNEYYLVASTFGLSKAELFRLAQSAVEFVFADDE 1154 + P SI +DD F + + Y V + FG +K + +A + ++ + DD+ Sbjct: 276 PIDKFFQMNVPFSINSDDPAYFGGYILDNYKAVHTRFGFTKDQWKIIALNGIKGSWCDDQ 335 Query: 1155 VKKSLRAAFE 1184 K L + E Sbjct: 336 RKNELISLVE 345
>Q9NZK5:CECR1_HUMAN Cat eye syndrome critical region protein 1 precursor - Homo sapiens| (Human) Length = 511 Score = 56.6 bits (135), Expect = 2e-07 Identities = 75/299 (25%), Positives = 120/299 (40%), Gaps = 22/299 (7%) Frame = +3 Query: 309 FRLFDLFHILTTDHDTVTRIAKEVIGDFAAENVVYLEIRTTPKNNEAKGMTKRSYMNAVV 488 F + L H D V R +E F +NV+Y+EIR Sbjct: 212 FTISGLIHYAPVFRDYVFRSMQE----FYEDNVLYMEIRAR------------------- 248 Query: 489 KGLKSVEDVDVVLNDEKISCAPMSDFGG---DTKRKKIYVRLLLSIDRRETTSAALDTVN 659 L V ++ +DE+ S + +T + I ++++ S R + + +++ Sbjct: 249 --LLPVYELSGEHHDEEWSVKTYQEVAQKFVETHPEFIGIKIIYSDHRSKDVAVIAESIR 306 Query: 660 LALELKDEG---VIGIDLSGNPVVGE-WETYLPALERAKELGI--PTTIHCGEVP----- 806 +A+ L+ + V G DL G+ G Y AL + G+ P H GE Sbjct: 307 MAMGLRIKFPTVVAGFDLVGHEDTGHSLHDYKEALMIPAKDGVKLPYFFHAGETDWQGTS 366 Query: 807 -NRKEIQAMLDFCPQRLGHVCCLDDE------EWKKLKSSMIPVEICLTSNVMTGGTPSL 965 +R + A++ R+GH L WKK IP+E+C SN + L Sbjct: 367 IDRNILDALM-LNTTRIGHGFALSKHPAVRTYSWKK----DIPIEVCPISNQVLKLVSDL 421 Query: 966 ELHHFADLYNAKHPLSICTDDSGLF-STSLSNEYYLVASTFGLSKAELFRLAQSAVEFV 1139 H A L HP+ I +DD +F + LS ++Y V G KA+L L Q A+ + Sbjct: 422 RNHPVATLMATGHPMVISSDDPAMFGAKGLSYDFYEVFMGIGGMKADLRTLKQLAMNSI 480
>Q5RC46:CECR1_PONPY Cat eye syndrome critical region protein 1 homolog precursor - Pongo| pygmaeus (Orangutan) Length = 511 Score = 55.1 bits (131), Expect = 7e-07 Identities = 74/299 (24%), Positives = 119/299 (39%), Gaps = 22/299 (7%) Frame = +3 Query: 309 FRLFDLFHILTTDHDTVTRIAKEVIGDFAAENVVYLEIRTTPKNNEAKGMTKRSYMNAVV 488 F + L H D V + +E F +NV+Y+EIR Sbjct: 212 FTISGLIHYAPVFRDYVFQSMQE----FYEDNVLYMEIRAR------------------- 248 Query: 489 KGLKSVEDVDVVLNDEKISCAPMSDFGG---DTKRKKIYVRLLLSIDRRETTSAALDTVN 659 L V ++ +DE+ S + +T + I ++++ S R + + +++ Sbjct: 249 --LLPVYELSGEHHDEEWSVKTYQEVAQKFVETHPEFIGIKIIYSDHRSKDVAVIAESIR 306 Query: 660 LALELKDEG---VIGIDLSGNPVVGE-WETYLPALERAKELGI--PTTIHCGEVP----- 806 A+ L+ + V G DL G G + Y AL + G+ P H GE Sbjct: 307 TAMGLRTKFPTVVAGFDLVGREDTGHSLQDYKEALMIPAKGGVKLPYFFHAGETDWQGTS 366 Query: 807 -NRKEIQAMLDFCPQRLGHVCCLDDE------EWKKLKSSMIPVEICLTSNVMTGGTPSL 965 +R + A++ R+GH L WKK IP+E+C SN + L Sbjct: 367 IDRNILDALM-LNTTRIGHGFALSKHPAVRAYSWKK----DIPIEVCPISNQVLKLVSDL 421 Query: 966 ELHHFADLYNAKHPLSICTDDSGLF-STSLSNEYYLVASTFGLSKAELFRLAQSAVEFV 1139 H A L HP+ I +DD +F + LS ++Y V G KA+L L Q A+ + Sbjct: 422 RNHPVATLMATGHPMVISSDDPAIFGAKGLSYDFYEVFMGIGGMKADLRTLKQLAMNSI 480
>Q2TZN9:ADA_ASPOR Adenosine deaminase - Aspergillus oryzae| Length = 351 Score = 54.7 bits (130), Expect = 9e-07 Identities = 75/344 (21%), Positives = 130/344 (37%), Gaps = 6/344 (1%) Frame = +3 Query: 156 LPKVELHAHLNGSVRNSTLLELAK--ELGDKGVIVYEDVKDVIMK--NDRSLPECFRLFD 323 LPK E H HL G + + ELAK + YE ++ + + + SL + R + Sbjct: 13 LPKCEHHVHLEGCLAPDLIFELAKRNNVSLPNEPAYESIEALSHRYGHFTSLDDFLRFYF 72 Query: 324 LFHILTTDHDTVTRIAKEVIGDFAAENVVYLEIRTTPKNNEAKGMTKRSYMNAVVKGLKS 503 + + +A A+ V + E+ P+ + +G+ + ++ V G + Sbjct: 73 IGMSVLHHESDFADLAWAYFQKAHADGVHHAEVFFDPQVHRDRGIPYETIVSGFVAGCQR 132 Query: 504 VEDVDVVLNDEKISCAPMSDFGGDTKRKKIYVRLLLSIDRRETTSAALDTVNLALELKDE 683 E + G T+ +VR L + ALD + +E Sbjct: 133 AE----------------RELGLTTRLILCFVRHLPVDNAARVYQEALDQEH----FDNE 172 Query: 684 GVIGIDLSGNPVVGEWETYLPALERAKELGIPTTIHCGEVPNRKEIQAMLDFCPQRLGHV 863 V G+ S V + + A GI T H GE + I A L+ QR+ H Sbjct: 173 VVHGLGWSSTEVGPPKDMFRELYSSASAKGIRLTAHAGEEGDPSYISAALELGAQRIDHG 232 Query: 864 CCL--DDEEWKKLKSSMIPVEICLTSNVMTGGTPSLELHHFADLYNAKHPLSICTDDSGL 1037 L D +K+ I + +C SN+ S+ +A SI +DD Sbjct: 233 IRLVEDPVLMEKVVRDRIMLTVCPISNLQLRCVESIAHVPIRKFLDAGVMFSINSDDPAY 292 Query: 1038 FSTSLSNEYYLVASTFGLSKAELFRLAQSAVEFVFADDEVKKSL 1169 F + + Y V F L+ E +A+++++ + +E K L Sbjct: 293 FGGYILDNYCAVQEAFQLTVDEWRVIAENSIKGSWIGEERKTEL 336
>Q4X1Q4:ADA_ASPFU Adenosine deaminase - Aspergillus fumigatus (Sartorya fumigata)| Length = 354 Score = 52.4 bits (124), Expect = 4e-06 Identities = 76/350 (21%), Positives = 126/350 (36%), Gaps = 12/350 (3%) Frame = +3 Query: 156 LPKVELHAHLNGSVRNSTLLELAK----ELGDKGVIVYEDVKDVIMKNDRSLPECFRLFD 323 LPK E H HL G V + +LA+ +L + + + D Sbjct: 13 LPKCEHHVHLEGCVTPELIFQLAEKNNIQLPNPATHPAYASVEALRARYAEFTSLNDFLD 72 Query: 324 L-FHILTTDH--DTVTRIAKEVIGDFAAENVVYLEIRTTPKNNEAKGMTKRSYMNAVVKG 494 FH ++ H +A A+ V + E+ P+ ++A+G+ + ++ G Sbjct: 73 FYFHGMSVLHHQSDFEELAWAYFQKAHADGVHHAEVFFDPQVHQARGIDYETVVSGFTAG 132 Query: 495 LKSVEDVDVVLNDEKISCAPMSDFGGDTKRKKIYVRLLLSIDRRETTSAALDTVNLAL-- 668 K E + + RL+L R +A LAL Sbjct: 133 CKRAE-----------------------RELGLSTRLILCFVRHLPVDSATKLYELALAS 169 Query: 669 -ELKDEGVIGIDLSGNPVVGEWETYLPALERAKELGIPTTIHCGEVPNRKEIQAMLDFCP 845 + V G+ S + V + + A GI T H GE + I L+ Sbjct: 170 NHFESRVVHGLGWSSSEVGPPKDMFREIYASASGKGIRLTAHAGEEGDPTYISTALELGA 229 Query: 846 QRLGHVCCL--DDEEWKKLKSSMIPVEICLTSNVMTGGTPSLELHHFADLYNAKHPLSIC 1019 +R+ H L D E +++ I + +C SNV S+E +A SI Sbjct: 230 RRIDHGIRLVEDPELMERVAREGIMLTVCPLSNVRLRCVQSVEQVPIRKFLDAGVKFSIN 289 Query: 1020 TDDSGLFSTSLSNEYYLVASTFGLSKAELFRLAQSAVEFVFADDEVKKSL 1169 +DD F + + Y V F LS E +A+++V + D+ K L Sbjct: 290 SDDPAYFGGYILDNYCAVQEAFQLSILEWRVIAENSVNESWIDEARKAEL 339
>P53909:ADA_YEAST Adenosine deaminase - Saccharomyces cerevisiae (Baker's yeast)| Length = 347 Score = 47.4 bits (111), Expect = 1e-04 Identities = 85/357 (23%), Positives = 141/357 (39%), Gaps = 19/357 (5%) Frame = +3 Query: 156 LPKVELHAHLNGSVRNSTLLELAKELGDKGVIVYEDVKDVIMKNDRSLPECFRLF-DLFH 332 LPK E H HL G++ L LAK +I+ E K+ L E ++ F DL Sbjct: 10 LPKCEHHLHLEGTLEPDLLFPLAKR---NDIILPEG----FPKSVEELNEKYKKFRDLQD 62 Query: 333 ILTTDH-DTVTRIAKEVIGDFA--------AENVVYLEIRTTPKNNEAKGMTKRSYMNAV 485 L + T I+++ D A + +V+ E+ P+++ ++G++ + V Sbjct: 63 FLDYYYIGTNVLISEQDFFDLAWAYFKKVHKQGLVHAEVFYDPQSHTSRGIS----IETV 118 Query: 486 VKGLKSVEDVDVVLNDEKISCAPMSDFGGDTKRKKIYVRLLLSIDRRETTSAALDTVNLA 665 KG + D S+FG I +L++ + R L T+ A Sbjct: 119 TKGFQRACD------------KAFSEFG-------ITSKLIMCLLRHIEPEECLKTIEEA 159 Query: 666 LELKDEGVI---GIDLSGNPVVGEW--ETYLPALERAKELGIPTTIHCGEVPNRKEIQAM 830 +G I G+D + P E Y A K+L + T H GE + + Sbjct: 160 TPFIKDGTISALGLDSAEKPFPPHLFVECYGKAASLNKDLKL--TAHAGEEGPAQFVSDA 217 Query: 831 LDFCP-QRLGH--VCCLDDEEWKKLKSSMIPVEICLTSNVMTGGTPSLELHHFADLYNAK 1001 LD R+ H D+E +L + IC SNV S+ + Sbjct: 218 LDLLQVTRIDHGINSQYDEELLDRLSRDQTMLTICPLSNVKLQVVQSVSELPLQKFLDRD 277 Query: 1002 HPLSICTDDSGLFSTSLSNEYYLVASTFGLSKAELF-RLAQSAVEFVFADDEVKKSL 1169 P S+ +DD F + + Y V+ F E + R+A++A++ + DD+ K L Sbjct: 278 VPFSLNSDDPAYFGGYILDVYTQVSKDFPHWDHETWGRIAKNAIKGSWCDDKRKNGL 334
>P58780:CECR1_PIG Cat eye syndrome critical region protein 1 homolog precursor - Sus| scrofa (Pig) Length = 510 Score = 46.6 bits (109), Expect = 2e-04 Identities = 54/198 (27%), Positives = 81/198 (40%), Gaps = 15/198 (7%) Frame = +3 Query: 591 IYVRLLLSIDRRETTSAALDTVNLALELK---DEGVIGIDLSGNPVVGE-WETYLPALER 758 I ++L+ S R + S ++V A+EL+ + V G DL G G Y AL Sbjct: 281 IGIKLIYSDHRSKDVSLIKESVQRAMELRAKFPQMVAGFDLVGREDTGHSLYDYKEALMI 340 Query: 759 AKELGI--PTTIHCGEVP------NRKEIQAMLDFCPQRLGHVCCLDDEE--WKKLKSSM 908 G+ P H GE +R + A++ R+GH L W Sbjct: 341 PASRGVKLPYFFHAGETDWQGTSADRNLLDALI-LNSTRIGHGFALSKHPAVWADAWRKD 399 Query: 909 IPVEICLTSNVMTGGTPSLELHHFADLYNAKHPLSICTDDSGLF-STSLSNEYYLVASTF 1085 IP+E+C SN + L H A L +P+ I +DD F + LS ++Y Sbjct: 400 IPLEVCPISNQVLKLVSDLRNHPAAVLMATGYPMVISSDDPAAFGAKGLSYDFYEAFMGL 459 Query: 1086 GLSKAELFRLAQSAVEFV 1139 G A+L L Q A+ + Sbjct: 460 GGLTADLRTLKQLAMNSI 477
>Q6FP78:ADA_CANGA Adenosine deaminase - Candida glabrata (Yeast) (Torulopsis glabrata)| Length = 347 Score = 39.7 bits (91), Expect = 0.030 Identities = 71/364 (19%), Positives = 139/364 (38%), Gaps = 12/364 (3%) Frame = +3 Query: 141 AWCVALPKVELHAHLNGSVRNSTLLELAKELGDKGVIVYEDVKDVIMKNDRSLPECFRLF 320 ++ + LPK E H HL G++ L LAK + + + + + Sbjct: 5 SFLLELPKCEHHLHLEGTLEPDLLFPLAKRNNIQLPDHFPQTPEELAVRYTQFKDLQDFL 64 Query: 321 DLFHILTT---DHDTVTRIAKEVIGDFAAENVVYLEIRTTPKNNEAKGMTKRSYMNAVVK 491 D ++I T + +A + + +V+ E+ P+++ +G++ + V + Sbjct: 65 DYYYIGTNVLLKEEDFFDLAWAYFTKVSKQGLVHAELFYDPQSHTTRGVS----LETVTR 120 Query: 492 GLKSVEDVDVVLNDEKISCAPMSDFGGDTKRKKIYVRLLLSIDRRETTSAALDTVNLALE 671 G + +C + G T +L++ + R L T+ A + Sbjct: 121 GFER-------------ACKKAHEELGITS------KLIMCLLRHLPPQDCLQTIEEAEQ 161 Query: 672 LKDEGVI---GIDLSGNPVVGEWETYLPALERAKELG--IPTTIHCGEVPNRKEIQAMLD 836 L GVI G+D + P ++ ERA ++ + T H GE + + LD Sbjct: 162 LIKSGVIHGLGLDSAEKPFPP--SLFVECYERAAKINPELRLTAHAGEEGTHQFVSDALD 219 Query: 837 FC-PQRLGH-VCCLDDEE-WKKLKSSMIPVEICLTSNVMTGGTPSLELHHFADLYNAKHP 1007 R+ H V EE +L + +C SNV S++ + Sbjct: 220 LLNVTRIDHGVNSKQSEELMARLAEQQTLLTVCPLSNVKLQVVQSVKEIPLQLFLDKNIA 279 Query: 1008 LSICTDDSGLFSTSLSNEYYLVASTFGLSKAELF-RLAQSAVEFVFADDEVKKSLRAAFE 1184 S+ +DD F + + YY V F +++ R+A++ + + + + K+ L A + Sbjct: 280 FSLNSDDPAYFGGYILDNYYQVNKDFPDWDFKVWERIAKNGINGSWCEQKRKEELLAKVD 339 Query: 1185 HAAA 1196 A Sbjct: 340 AVVA 343
>P47386:Y140_MYCGE Uncharacterized ATP-dependent helicase MG140 - Mycoplasma genitalium| Length = 1113 Score = 37.7 bits (86), Expect = 0.11 Identities = 58/232 (25%), Positives = 99/232 (42%), Gaps = 12/232 (5%) Frame = +3 Query: 168 ELHAHLNGSVRNSTLLELAKELGDKGVIVYEDVKDVIMKNDRSLPECFRLFDLFHILTTD 347 +L A N + ++ L+ + K D+ V + DV D I KN+R+L E + LTT Sbjct: 787 DLIAFTNNRIYDNELIFMNKANADQRVFIVHDVIDGIWKNNRNLQEARDVVQRLEQLTTT 846 Query: 348 HDTVTRIAKEVIGDFAAENVVYL-EIRTTPKNNEAKGMTK--RSYMNAVVKGLKSV--ED 512 +D + A+ + YL + + P NE + Y VK +++V ++ Sbjct: 847 NDYKKSLGVICFNKNQADLIEYLIDKQNNPLLNEWRERQNDVGEYEGLFVKNIENVQGDE 906 Query: 513 VDVVL----NDEKI-SCAPMSDFGGDTKRKKIYVRLLLSIDRRETTSAALDTVNLALELK 677 D+++ D + S P+S GG+ RL ++I R A + L + Sbjct: 907 RDIIIFSLGYDRSVNSYGPISKQGGEN-------RLNVAITR------AKQRIELFKTNR 953 Query: 678 DEGVIGIDLS--GNPVVGEWETYLPALERAKELGIPTTIHCGEVPNRKEIQA 827 E G+ S G+ ++ E+ Y A+ AK G T + RKE +A Sbjct: 954 GEDYNGLSSSSLGSKLLVEYLLYCEAM--AKNQGEKITF---QAVKRKETKA 1000
>Q08490:SGO1_YEAST Shugoshin - Saccharomyces cerevisiae (Baker's yeast)| Length = 590 Score = 35.8 bits (81), Expect = 0.43 Identities = 47/245 (19%), Positives = 97/245 (39%), Gaps = 7/245 (2%) Frame = +3 Query: 54 TSRAPGRRRSKTKPAAMGTQTSEAEKEMRAWCVALPKVELHAHLNGSVRNSTLLELAKEL 233 T R G+ T P+ +EK + A V +++H L S RN K L Sbjct: 368 TRRTRGKAVDYTLPSLRAKMRRPSEKLVDATTV----IDIH-DLQVSKRNRETSHKRKSL 422 Query: 234 GDKGVIVYEDVKDVIMKNDRSLPECFRLFDLFH------ILTTDHDTVTRIAKEVIGDFA 395 + +++V++ D P+ + D H + T+++++ + K++ + + Sbjct: 423 SQDSIPDEPQLREVVVSKDYGTPKGKKTEDEIHEDTAHLMTTSNNNSNNKNEKKLTSNNS 482 Query: 396 AE-NVVYLEIRTTPKNNEAKGMTKRSYMNAVVKGLKSVEDVDVVLNDEKISCAPMSDFGG 572 + + L+I +N + TK+ + NA+V L+DE + P G Sbjct: 483 PKKSSPLLDITNKSENKKKSTRTKKLFKNAIVNN----------LSDENSTTRPSKSSKG 532 Query: 573 DTKRKKIYVRLLLSIDRRETTSAALDTVNLALELKDEGVIGIDLSGNPVVGEWETYLPAL 752 + Y + D + ++ +++ L ++ + DL GN G+ + P Sbjct: 533 TSNNNNNY----NNFDNNNSNINNVNNKSVSFRLNEDDLAVFDLFGN---GKAVKHQPKT 585 Query: 753 ERAKE 767 R K+ Sbjct: 586 YRTKK 590
>O83085:ADD_TREPA Adenosine deaminase - Treponema pallidum| Length = 299 Score = 35.8 bits (81), Expect = 0.43 Identities = 28/131 (21%), Positives = 54/131 (41%), Gaps = 3/131 (2%) Frame = +3 Query: 696 IDLSGNPVVGEWETYLPALERAKELGIPTTIHCGEVPNRKEIQAMLDFC---PQRLGHVC 866 IDL G + E ++ + A++ + H GE + + ++ ++ + G Sbjct: 153 IDLYGPEISEGIEDFIYIFKLAEKYHLKKKAHVGEFSDAQSVRHFVEIFNLDEVQHGIGA 212 Query: 867 CLDDEEWKKLKSSMIPVEICLTSNVMTGGTPSLELHHFADLYNAKHPLSICTDDSGLFST 1046 D+ + L + +C TSNVM LE H + +A + + TDD F Sbjct: 213 ATDENVLRFLAERKVRCNVCPTSNVMLNAVECLEKHPIKKMMDAGVRVGLGTDDLLFFGK 272 Query: 1047 SLSNEYYLVAS 1079 + S + + + S Sbjct: 273 TNSEQLFDMVS 283
>Q8WWY8:LIPH_HUMAN Lipase member H precursor - Homo sapiens (Human)| Length = 451 Score = 33.1 bits (74), Expect = 2.8 Identities = 20/62 (32%), Positives = 34/62 (54%) Frame = +3 Query: 471 YMNAVVKGLKSVEDVDVVLNDEKISCAPMSDFGGDTKRKKIYVRLLLSIDRRETTSAALD 650 +M+ +VKGL SVED++VV+ D + +K +K+ + L ID+ A+LD Sbjct: 87 WMDDLVKGLLSVEDMNVVVVDWNRGATTLIYTHASSKTRKVAMVLKEFIDQMLAEGASLD 146 Query: 651 TV 656 + Sbjct: 147 DI 148
>Q6L8L2:KAIB_ACAMR Circadian clock protein kaiB - Acaryochloris marina| Length = 104 Score = 32.3 bits (72), Expect = 4.8 Identities = 27/93 (29%), Positives = 41/93 (44%), Gaps = 3/93 (3%) Frame = +3 Query: 585 KKIYVRLLLSIDRRETTSAALDTVNLALELKDEGVIG---IDLSGNPVVGEWETYLPALE 755 +K YV L + AL T+N LE + +GV ID+ NP + E + L Sbjct: 5 RKTYVLKLYVAGNTPNSVRALRTLNHILETEFQGVYALKVIDVLKNPQLAEEDKILATPT 64 Query: 756 RAKELGIPTTIHCGEVPNRKEIQAMLDFCPQRL 854 AK L P G++ +R+ + LD + L Sbjct: 65 LAKVLPPPVRKIIGDLSDRERVLIGLDLLYEEL 97
>Q5BAB7:BUD32_EMENI Serine/threonine-protein kinase bud32 - Emericella nidulans| (Aspergillus nidulans) Length = 285 Score = 32.0 bits (71), Expect = 6.2 Identities = 24/78 (30%), Positives = 33/78 (42%), Gaps = 24/78 (30%) Frame = +3 Query: 615 IDRRETTSAALDTVNLALELKDEGV-----IGID----------------LSGNPV---V 722 +DRR T + L +L EGV +G+D + G PV + Sbjct: 66 LDRRLTRARILQEARCLQKLVKEGVSVPALLGVDWEPSAGDGSSWLVMEWIEGEPVRVIL 125 Query: 723 GEWETYLPALERAKELGI 776 EWE YL +ER K LG+ Sbjct: 126 EEWEAYLKGIEREKRLGL 143
>P47024:YJ41B_YEAST Transposon Ty4-J Gag-Pol polyprotein - Saccharomyces cerevisiae| (Baker's yeast) Length = 1803 Score = 31.6 bits (70), Expect = 8.1 Identities = 30/109 (27%), Positives = 46/109 (42%), Gaps = 3/109 (2%) Frame = +3 Query: 147 CVALPKVELHAHLNGSVRNSTLLELAKELGD---KGVIVYEDVKDVIMKNDRSLPECFRL 317 CV+ + ELHA G + TL KELG+ +++ D K I +RS + Sbjct: 1680 CVSSTEAELHAIYEGYADSETLKVTLKELGEGDNNDIVMITDSKPAIQGLNRSYQQ---- 1735 Query: 318 FDLFHILTTDHDTVTRIAKEVIGDFAAENVVYLEIRTTPKNNEAKGMTK 464 + T I E+I + E + L ++ T K N A +TK Sbjct: 1736 ---------PKEKFTWIKTEIIKEKIKEKSIKL-LKITGKGNIADLLTK 1774
>P0C2J7:YH41B_YEAST Transposon Ty4-H Gag-Pol polyprotein - Saccharomyces cerevisiae| (Baker's yeast) Length = 1802 Score = 31.6 bits (70), Expect = 8.1 Identities = 30/109 (27%), Positives = 46/109 (42%), Gaps = 3/109 (2%) Frame = +3 Query: 147 CVALPKVELHAHLNGSVRNSTLLELAKELGD---KGVIVYEDVKDVIMKNDRSLPECFRL 317 CV+ + ELHA G + TL KELG+ +++ D K I +RS + Sbjct: 1679 CVSSTEAELHAIYEGYADSETLKVTLKELGEGDNNDIVMITDSKPAIQGLNRSYQQ---- 1734 Query: 318 FDLFHILTTDHDTVTRIAKEVIGDFAAENVVYLEIRTTPKNNEAKGMTK 464 + T I E+I + E + L ++ T K N A +TK Sbjct: 1735 ---------PKEKFTWIKTEIIKEKIKEKSIKL-LKITGKGNIADLLTK 1773
>Q9UWN5:TPIS_METFE Triosephosphate isomerase - Methanothermus fervidus| Length = 222 Score = 31.6 bits (70), Expect = 8.1 Identities = 33/132 (25%), Positives = 51/132 (38%) Frame = +3 Query: 189 GSVRNSTLLELAKELGDKGVIVYEDVKDVIMKNDRSLPECFRLFDLFHILTTDHDTVTRI 368 G S LLE AKE G KG +V K + + + + + D+ I+ T++ + Sbjct: 70 GGHTGSVLLECAKEAGAKGSLVNHSEKRMKLADISKVVKKLSENDMISIVCTNNVETSAA 129 Query: 369 AKEVIGDFAAENVVYLEIRTTPKNNEAKGMTKRSYMNAVVKGLKSVEDVDVVLNDEKISC 548 A + DF A P G+ VV+ +VE V V D ++ C Sbjct: 130 AAALSPDFVA---------VEPPELIGSGIPVSKAKPEVVE--NTVEAVKTVNPDVRVLC 178 Query: 549 APMSDFGGDTKR 584 G D K+ Sbjct: 179 GAGISSGEDVKK 190
>Q62230:SN_MOUSE Sialoadhesin precursor - Mus musculus (Mouse)| Length = 1694 Score = 31.6 bits (70), Expect = 8.1 Identities = 12/34 (35%), Positives = 18/34 (52%) Frame = +3 Query: 768 LGIPTTIHCGEVPNRKEIQAMLDFCPQRLGHVCC 869 L P ++H P + A+L P+RLGH+ C Sbjct: 967 LAAPVSLHVSYTPRHVTLSALLSTDPERLGHLVC 1000
>Q6F598:RGYR_PYRKO Reverse gyrase [Includes: Helicase - Pyrococcus kodakaraensis| (Thermococcus kodakaraensis) Length = 1711 Score = 31.6 bits (70), Expect = 8.1 Identities = 31/128 (24%), Positives = 57/128 (44%), Gaps = 3/128 (2%) Frame = +3 Query: 168 ELHAHLNGSVRNSTLLELAK--ELGDKGVIVYEDVKDVIMKNDRSLPECFRLFDLFHILT 341 +LHA L +RN EL K E +G+ + + + ++ R L E R + Sbjct: 469 KLHARLRRLIRNIPQFELLKIEEALAEGLPIENEFHNHVLGVFRELVEFLRR------VL 522 Query: 342 TDHDTVTRIAKE-VIGDFAAENVVYLEIRTTPKNNEAKGMTKRSYMNAVVKGLKSVEDVD 518 D + + ++A++ I E Y+EI +A G T R + + KGL Sbjct: 523 RDEEVLRKLAEDPFISLVKEEGKWYIEIPDVRTYIQATGRTSRLFAGGITKGLSV----- 577 Query: 519 VVLNDEKI 542 +++++EK+ Sbjct: 578 LIVDNEKV 585
>O66990:PYRC_AQUAE Dihydroorotase - Aquifex aeolicus| Length = 422 Score = 31.6 bits (70), Expect = 8.1 Identities = 20/60 (33%), Positives = 29/60 (48%), Gaps = 6/60 (10%) Frame = +3 Query: 672 LKDEGVIGIDLSGNPVVGEWETYLPALERAKELGIPTTIHCGE------VPNRKEIQAML 833 LK+ G + G+PV+ ALE A +LG+P HC + V N E+ A+L Sbjct: 142 LKEAGCVAFTDDGSPVMDS-SVMRKALELASQLGVPIMDHCEDDKLAYGVINEGEVSALL 200 Database: uniprot_sprot.fasta.out Posted date: Jul 19, 2007 5:58 PM Number of letters in database: 100,686,439 Number of sequences in database: 274,295 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 274295 Number of Hits to DB: 219,349,356 Number of extensions: 4654216 Number of successful extensions: 13621 Number of sequences better than 10.0: 82 Number of HSP's gapped: 13466 Number of HSP's successfully gapped: 87 Length of query: 458 Length of database: 100,686,439 Length adjustment: 117 Effective length of query: 341 Effective length of database: 68,593,924 Effective search space: 23390528084 Effective search space used: 23390528084 Neighboring words threshold: 12 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
