ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | FLbaf105e18 |
|---|---|
| Clone Library Name | barley_pub |
>P42168:KC1A_CAEEL Casein kinase I isoform alpha - Caenorhabditis elegans| Length = 341 Score = 194 bits (492), Expect = 2e-48 Identities = 111/279 (39%), Positives = 161/279 (57%), Gaps = 3/279 (1%) Frame = +3 Query: 567 QYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYS 746 +YK+ RK+G G FG +YV V+ G E VA+K E ++ YE +VY Sbjct: 15 KYKLIRKIGSGSFGDIYVSINVTNGEE--------VAIKLESNRARHPQL--LYESKVYR 64 Query: 747 SLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISILE 926 L G GIP + + G + +Y VLVMD+LGPSL D++N + T V +A + I +E Sbjct: 65 ILQGGVGIPHIRWYGTEREYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMIGRIE 124 Query: 927 KLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFR 1106 +H K F+H D+KP+NFL+G KLFLID GLA K++++ + H+ Y + ++ Sbjct: 125 YVHVKNFIHRDIKPDNFLMGI--GRHCNKLFLIDFGLAKKYRDSRTRTHIPYREDKNL-T 181 Query: 1107 GTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNKS---FLVCKKKMS 1277 GT RYAS++AHLG SRRDD+ESL Y L++ RG LPWQG + K + +KKM+ Sbjct: 182 GTARYASINAHLGIEQSRRDDMESLGYVLMYFNRGTLPWQGLKAATKKQKYEKISEKKMT 241 Query: 1278 ISPDLMCCYCAPPFKLFLETVTNMKFDEEPNYPKLISLF 1394 S + +C F ++L ++FDE P+Y L LF Sbjct: 242 TSVEHLCKGFPAEFPMYLSYTRGLRFDESPDYMYLRQLF 280
>P67963:KC1A_XENLA Casein kinase I isoform alpha - Xenopus laevis (African clawed frog)| Length = 337 Score = 193 bits (490), Expect = 4e-48 Identities = 109/279 (39%), Positives = 163/279 (58%), Gaps = 3/279 (1%) Frame = +3 Query: 567 QYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYS 746 +YK+ RK+G G FG +Y+ ++ G E VA+K E + ++ YE ++Y Sbjct: 16 KYKLVRKIGSGSFGDIYLAINITNGEE--------VAVKLESQKARHPQL--LYESKLYK 65 Query: 747 SLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISILE 926 L G GIP + + G++ DY VLVMD+LGPSL D++N + T V +A + IS +E Sbjct: 66 ILQGGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIE 125 Query: 927 KLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFR 1106 +H K F+H D+KP+NFL+G KLFLID GLA K+++ + QH+ Y + ++ Sbjct: 126 YVHTKNFIHRDIKPDNFLMGI--GRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNL-T 182 Query: 1107 GTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNKS---FLVCKKKMS 1277 GT RYAS++AHLG SRRDD+ESL Y L++ R LPWQG + K + +KKMS Sbjct: 183 GTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMS 242 Query: 1278 ISPDLMCCYCAPPFKLFLETVTNMKFDEEPNYPKLISLF 1394 +++C F ++L ++F+E P+Y L LF Sbjct: 243 TPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLF 281
>P67829:KC1A_SHEEP Casein kinase I isoform alpha - Ovis aries (Sheep)| Length = 325 Score = 193 bits (490), Expect = 4e-48 Identities = 109/279 (39%), Positives = 163/279 (58%), Gaps = 3/279 (1%) Frame = +3 Query: 567 QYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYS 746 +YK+ RK+G G FG +Y+ ++ G E VA+K E + ++ YE ++Y Sbjct: 16 KYKLVRKIGSGSFGDIYLAINITNGEE--------VAVKLESQKARHPQL--LYESKLYK 65 Query: 747 SLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISILE 926 L G GIP + + G++ DY VLVMD+LGPSL D++N + T V +A + IS +E Sbjct: 66 ILQGGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIE 125 Query: 927 KLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFR 1106 +H K F+H D+KP+NFL+G KLFLID GLA K+++ + QH+ Y + ++ Sbjct: 126 YVHTKNFIHRDIKPDNFLMGI--GRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNL-T 182 Query: 1107 GTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNKS---FLVCKKKMS 1277 GT RYAS++AHLG SRRDD+ESL Y L++ R LPWQG + K + +KKMS Sbjct: 183 GTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMS 242 Query: 1278 ISPDLMCCYCAPPFKLFLETVTNMKFDEEPNYPKLISLF 1394 +++C F ++L ++F+E P+Y L LF Sbjct: 243 TPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLF 281
>P67828:KC1A_RABIT Casein kinase I isoform alpha - Oryctolagus cuniculus (Rabbit)| Length = 325 Score = 193 bits (490), Expect = 4e-48 Identities = 109/279 (39%), Positives = 163/279 (58%), Gaps = 3/279 (1%) Frame = +3 Query: 567 QYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYS 746 +YK+ RK+G G FG +Y+ ++ G E VA+K E + ++ YE ++Y Sbjct: 16 KYKLVRKIGSGSFGDIYLAINITNGEE--------VAVKLESQKARHPQL--LYESKLYK 65 Query: 747 SLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISILE 926 L G GIP + + G++ DY VLVMD+LGPSL D++N + T V +A + IS +E Sbjct: 66 ILQGGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIE 125 Query: 927 KLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFR 1106 +H K F+H D+KP+NFL+G KLFLID GLA K+++ + QH+ Y + ++ Sbjct: 126 YVHTKNFIHRDIKPDNFLMGI--GRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNL-T 182 Query: 1107 GTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNKS---FLVCKKKMS 1277 GT RYAS++AHLG SRRDD+ESL Y L++ R LPWQG + K + +KKMS Sbjct: 183 GTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMS 242 Query: 1278 ISPDLMCCYCAPPFKLFLETVTNMKFDEEPNYPKLISLF 1394 +++C F ++L ++F+E P+Y L LF Sbjct: 243 TPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLF 281
>Q8BK63:KC1A_MOUSE Casein kinase I isoform alpha - Mus musculus (Mouse)| Length = 337 Score = 193 bits (490), Expect = 4e-48 Identities = 109/279 (39%), Positives = 163/279 (58%), Gaps = 3/279 (1%) Frame = +3 Query: 567 QYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYS 746 +YK+ RK+G G FG +Y+ ++ G E VA+K E + ++ YE ++Y Sbjct: 16 KYKLVRKIGSGSFGDIYLAINITNGEE--------VAVKLESQKARHPQL--LYESKLYK 65 Query: 747 SLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISILE 926 L G GIP + + G++ DY VLVMD+LGPSL D++N + T V +A + IS +E Sbjct: 66 ILQGGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIE 125 Query: 927 KLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFR 1106 +H K F+H D+KP+NFL+G KLFLID GLA K+++ + QH+ Y + ++ Sbjct: 126 YVHTKNFIHRDIKPDNFLMGI--GRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNL-T 182 Query: 1107 GTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNKS---FLVCKKKMS 1277 GT RYAS++AHLG SRRDD+ESL Y L++ R LPWQG + K + +KKMS Sbjct: 183 GTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMS 242 Query: 1278 ISPDLMCCYCAPPFKLFLETVTNMKFDEEPNYPKLISLF 1394 +++C F ++L ++F+E P+Y L LF Sbjct: 243 TPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLF 281
>P48729:KC1A_HUMAN Casein kinase I isoform alpha - Homo sapiens (Human)| Length = 337 Score = 193 bits (490), Expect = 4e-48 Identities = 109/279 (39%), Positives = 163/279 (58%), Gaps = 3/279 (1%) Frame = +3 Query: 567 QYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYS 746 +YK+ RK+G G FG +Y+ ++ G E VA+K E + ++ YE ++Y Sbjct: 16 KYKLVRKIGSGSFGDIYLAINITNGEE--------VAVKLESQKARHPQL--LYESKLYK 65 Query: 747 SLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISILE 926 L G GIP + + G++ DY VLVMD+LGPSL D++N + T V +A + IS +E Sbjct: 66 ILQGGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIE 125 Query: 927 KLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFR 1106 +H K F+H D+KP+NFL+G KLFLID GLA K+++ + QH+ Y + ++ Sbjct: 126 YVHTKNFIHRDIKPDNFLMGI--GRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNL-T 182 Query: 1107 GTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNKS---FLVCKKKMS 1277 GT RYAS++AHLG SRRDD+ESL Y L++ R LPWQG + K + +KKMS Sbjct: 183 GTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMS 242 Query: 1278 ISPDLMCCYCAPPFKLFLETVTNMKFDEEPNYPKLISLF 1394 +++C F ++L ++F+E P+Y L LF Sbjct: 243 TPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLF 281
>P67962:KC1A_CHICK Casein kinase I isoform alpha - Gallus gallus (Chicken)| Length = 337 Score = 193 bits (490), Expect = 4e-48 Identities = 109/279 (39%), Positives = 163/279 (58%), Gaps = 3/279 (1%) Frame = +3 Query: 567 QYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYS 746 +YK+ RK+G G FG +Y+ ++ G E VA+K E + ++ YE ++Y Sbjct: 16 KYKLVRKIGSGSFGDIYLAINITNGEE--------VAVKLESQKARHPQL--LYESKLYK 65 Query: 747 SLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISILE 926 L G GIP + + G++ DY VLVMD+LGPSL D++N + T V +A + IS +E Sbjct: 66 ILQGGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIE 125 Query: 927 KLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFR 1106 +H K F+H D+KP+NFL+G KLFLID GLA K+++ + QH+ Y + ++ Sbjct: 126 YVHTKNFIHRDIKPDNFLMGI--GRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNL-T 182 Query: 1107 GTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNKS---FLVCKKKMS 1277 GT RYAS++AHLG SRRDD+ESL Y L++ R LPWQG + K + +KKMS Sbjct: 183 GTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMS 242 Query: 1278 ISPDLMCCYCAPPFKLFLETVTNMKFDEEPNYPKLISLF 1394 +++C F ++L ++F+E P+Y L LF Sbjct: 243 TPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLF 281
>P67827:KC1A_BOVIN Casein kinase I isoform alpha - Bos taurus (Bovine)| Length = 325 Score = 193 bits (490), Expect = 4e-48 Identities = 109/279 (39%), Positives = 163/279 (58%), Gaps = 3/279 (1%) Frame = +3 Query: 567 QYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYS 746 +YK+ RK+G G FG +Y+ ++ G E VA+K E + ++ YE ++Y Sbjct: 16 KYKLVRKIGSGSFGDIYLAINITNGEE--------VAVKLESQKARHPQL--LYESKLYK 65 Query: 747 SLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISILE 926 L G GIP + + G++ DY VLVMD+LGPSL D++N + T V +A + IS +E Sbjct: 66 ILQGGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIE 125 Query: 927 KLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFR 1106 +H K F+H D+KP+NFL+G KLFLID GLA K+++ + QH+ Y + ++ Sbjct: 126 YVHTKNFIHRDIKPDNFLMGI--GRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNL-T 182 Query: 1107 GTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNKS---FLVCKKKMS 1277 GT RYAS++AHLG SRRDD+ESL Y L++ R LPWQG + K + +KKMS Sbjct: 183 GTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMS 242 Query: 1278 ISPDLMCCYCAPPFKLFLETVTNMKFDEEPNYPKLISLF 1394 +++C F ++L ++F+E P+Y L LF Sbjct: 243 TPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLF 281
>P40235:HHP1_SCHPO Casein kinase I homolog hhp1 - Schizosaccharomyces pombe (Fission| yeast) Length = 365 Score = 193 bits (490), Expect = 4e-48 Identities = 106/282 (37%), Positives = 166/282 (58%), Gaps = 3/282 (1%) Frame = +3 Query: 567 QYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYS 746 +Y++ RK+G G FG +Y+G V G E VA+K E +K YE++VY Sbjct: 10 KYRIGRKIGSGSFGDIYLGTNVVSGEE--------VAIKLESTRAKHPQL--EYEYRVYR 59 Query: 747 SLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISILE 926 L+G GIP+V + G + DY +VMD+LGPSL D++N + + V +A + IS +E Sbjct: 60 ILSGGVGIPFVRWFGVECDYNAMVMDLLGPSLEDLFNFCNRKFSLKTVLLLADQLISRIE 119 Query: 927 KLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFR 1106 +H+K F+H D+KP+NFL+G ++ +ID GLA K+++ + H+ Y + ++ Sbjct: 120 FIHSKSFLHRDIKPDNFLMGI--GKRGNQVNIIDFGLAKKYRDHKTHLHIPYRENKNL-T 176 Query: 1107 GTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNKS---FLVCKKKMS 1277 GT RYAS++ HLG SRRDDLESL Y L++ RG LPWQG + K + +KK+S Sbjct: 177 GTARYASINTHLGIEQSRRDDLESLGYVLVYFCRGSLPWQGLKATTKKQKYEKIMEKKIS 236 Query: 1278 ISPDLMCCYCAPPFKLFLETVTNMKFDEEPNYPKLISLFDEL 1403 +++C F ++L +++FD++P+Y L LF +L Sbjct: 237 TPTEVLCRGFPQEFSIYLNYTRSLRFDDKPDYAYLRKLFRDL 278
>P40234:CKI2_SCHPO Casein kinase I homolog 2 - Schizosaccharomyces pombe (Fission yeast)| Length = 435 Score = 193 bits (490), Expect = 4e-48 Identities = 103/282 (36%), Positives = 167/282 (59%), Gaps = 3/282 (1%) Frame = +3 Query: 570 YKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYSS 749 Y+V RK+G+G FG ++ G + +A+KFE + S+ E++ Y Sbjct: 12 YRVGRKIGEGSFGVIFDGMNLLNNQL--------IAIKFEPKKSEAPQLRD--EYRTYKL 61 Query: 750 LNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISILEK 929 L G GIP V+Y G++G + +LV+D+LGPSL D++ G+ + VA A + +S ++ Sbjct: 62 LVGNAGIPNVYYFGQEGLHNILVIDLLGPSLEDLFEWCGRRFSVKTVAMTAKQMLSRVQT 121 Query: 930 LHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFRG 1109 +H K V+ D+KP+NFL+G+P S + ++++D G+A +++ + QH+ Y +R + G Sbjct: 122 IHEKNLVYRDIKPDNFLIGRPSSRNANMVYMVDFGMAKYYRDPKTKQHIPYSERKSL-SG 180 Query: 1110 TIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDN---KSFLVCKKKMSI 1280 T RY S++ HLGR SRRDDLESL + ++ LRG LPWQG + N K + +KK S Sbjct: 181 TARYMSINTHLGREQSRRDDLESLGHVFMYFLRGSLPWQGLKAANNKHKYEKISEKKQST 240 Query: 1281 SPDLMCCYCAPPFKLFLETVTNMKFDEEPNYPKLISLFDELI 1406 S +C F ++ V +++FDEEP+Y L LFD+++ Sbjct: 241 SISELCAGFPNEFSKYMTYVRSLEFDEEPDYAFLQELFDDVL 282
>Q8N752:KC1AL_HUMAN Casein kinase I isoform alpha-like - Homo sapiens (Human)| Length = 337 Score = 192 bits (488), Expect = 6e-48 Identities = 111/279 (39%), Positives = 162/279 (58%), Gaps = 3/279 (1%) Frame = +3 Query: 567 QYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYS 746 +YK+ RK+G G FG VY+G + G E VA+K E + K YE ++Y+ Sbjct: 16 KYKLVRKIGSGSFGDVYLGITTTNGEE--------VAVKLESQKVKHPQL--LYESKLYT 65 Query: 747 SLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISILE 926 L G GIP +H+ G++ D VLVMD+LGPSL D++N + T V +A + IS +E Sbjct: 66 ILQGGVGIPHMHWYGQEKDNNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIE 125 Query: 927 KLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFR 1106 +H K F+H D+KP+NFL+G KLFLID GLA K+++ + QH+ Y + + Sbjct: 126 YVHTKNFLHRDIKPDNFLMGT--GRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKHLI- 182 Query: 1107 GTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQG---DNKSFLVCKKKMS 1277 GT+RYAS++AHLG SRRDD+ESL Y ++ R LPWQG + K + +KKMS Sbjct: 183 GTVRYASINAHLGIEQSRRDDMESLGYVFMYFNRTSLPWQGLKAMTKKQKYEKISEKKMS 242 Query: 1278 ISPDLMCCYCAPPFKLFLETVTNMKFDEEPNYPKLISLF 1394 +++C F ++L ++F+E P+Y L LF Sbjct: 243 TPVEVLCKGFPAEFAMYLNYCRGLRFEEVPDYMYLRQLF 281
>P23291:KC11_YEAST Casein kinase I homolog 1 - Saccharomyces cerevisiae (Baker's yeast)| Length = 538 Score = 192 bits (488), Expect = 6e-48 Identities = 104/287 (36%), Positives = 170/287 (59%), Gaps = 7/287 (2%) Frame = +3 Query: 570 YKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYSS 749 YK+ +K+G+G FG ++ G + G VA+KFE R ++ E++ Y Sbjct: 69 YKIGKKIGEGSFGVLFEGTNMINGVP--------VAIKFEPRKTEAPQLRD--EYKTYKI 118 Query: 750 LNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISILEK 929 LNG IP+ +Y G++G + +LV+D+LGPSL D+++ G+ + V +AV+ I+++E Sbjct: 119 LNGTPNIPYAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRKFSVKTVVQVAVQMITLIED 178 Query: 930 LHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFRG 1109 LHA ++ D+KP+NFL+G+PG PD + LID G+A ++++ + QH+ Y ++ + G Sbjct: 179 LHAHDLIYRDIKPDNFLIGRPGQPDANNIHLIDFGMAKQYRDPKTKQHIPYREKKSL-SG 237 Query: 1110 TIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDN---KSFLVCKKKMSI 1280 T RY S++ HLGR SRRDD+E+L + + LRG LPWQG + N K + +KK S Sbjct: 238 TARYMSINTHLGREQSRRDDMEALGHVFFYFLRGHLPWQGLKAPNNKQKYEKIGEKKRST 297 Query: 1281 SPDLMCCYCAPPFKLFLETVTNMKFDEEPNY----PKLISLFDELIE 1409 + + F +LE V ++ F+E P+Y L+S+ D+L E Sbjct: 298 NVYDLAQGLPVQFGRYLEIVRSLSFEECPDYEGYRKLLLSVLDDLGE 344
>Q6QNM1:KC1_TOXGO Casein kinase I - Toxoplasma gondii| Length = 324 Score = 191 bits (486), Expect = 1e-47 Identities = 107/290 (36%), Positives = 173/290 (59%), Gaps = 3/290 (1%) Frame = +3 Query: 543 KVQVGHSPQYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGP 722 +V+VG +Y++ RK+G G FG +Y+G + G E VA+K E SK Sbjct: 2 EVRVGG--KYRLGRKIGSGSFGDIYIGANILTGDE--------VAIKLESIKSKHPQL-- 49 Query: 723 PYEWQVYSSLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIA 902 YE ++Y L G GIP VH+ G +GDY V+V+D+LGPSL D+++ + ++ V +A Sbjct: 50 LYESKLYKLLAGGIGIPMVHWYGIEGDYNVMVIDLLGPSLEDLFSICNRKLSLKTVLMLA 109 Query: 903 VEAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDY 1082 + ++ +E +H+K F+H D+KP+NFL+G+ +++ID GLA K+++ + QH+ Y Sbjct: 110 DQMLNRIEFVHSKNFIHRDIKPDNFLIGR--GKKMSVVYIIDFGLAKKYRDPKTQQHIPY 167 Query: 1083 DQRPDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNKS---F 1253 + ++ GT RYAS++ HLG SRRDDLE+L Y L++ RG LPWQG + K Sbjct: 168 REGKNL-TGTARYASINTHLGIEQSRRDDLEALGYVLMYFNRGSLPWQGLKATTKKDKYD 226 Query: 1254 LVCKKKMSISPDLMCCYCAPPFKLFLETVTNMKFDEEPNYPKLISLFDEL 1403 + +KKMS +++C + F +L +++F++ P+Y L LF +L Sbjct: 227 KIMEKKMSTPIEILCKHFPFEFITYLNYCRSLRFEDRPDYAYLRRLFKDL 276
>P97633:KC1A_RAT Casein kinase I isoform alpha - Rattus norvegicus (Rat)| Length = 325 Score = 191 bits (486), Expect = 1e-47 Identities = 109/279 (39%), Positives = 162/279 (58%), Gaps = 3/279 (1%) Frame = +3 Query: 567 QYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYS 746 +YK+ RK+G G FG +Y+ ++ G E VA+K E + ++ YE ++Y Sbjct: 16 KYKLVRKIGSGSFGDIYLAINITNGEE--------VAVKLESQKARHPQL--LYESKLYK 65 Query: 747 SLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISILE 926 L G GIP + + G+ DY VLVMD+LGPSL D++N + T V +A + IS +E Sbjct: 66 ILQGGVGIPHIRWYGQGKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIE 125 Query: 927 KLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFR 1106 +H K F+H D+KP+NFL+G KLFLID GLA K+++ + QH+ Y + ++ Sbjct: 126 YVHTKNFIHRDIKPDNFLMGI--GRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNL-T 182 Query: 1107 GTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNKS---FLVCKKKMS 1277 GT RYAS++AHLG SRRDD+ESL Y L++ R LPWQG + K + +KKMS Sbjct: 183 GTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMS 242 Query: 1278 ISPDLMCCYCAPPFKLFLETVTNMKFDEEPNYPKLISLF 1394 +++C F ++L ++F+E P+Y L LF Sbjct: 243 TPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLF 281
>P23292:KC12_YEAST Casein kinase I homolog 2 - Saccharomyces cerevisiae (Baker's yeast)| Length = 546 Score = 190 bits (483), Expect = 2e-47 Identities = 104/287 (36%), Positives = 170/287 (59%), Gaps = 7/287 (2%) Frame = +3 Query: 570 YKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYSS 749 YK+ +K+G+G FG ++ G + G VA+KFE R ++ E++ Y Sbjct: 76 YKIGKKIGEGSFGVLFEGTNMINGLP--------VAIKFEPRKTEAPQLKD--EYRTYKI 125 Query: 750 LNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISILEK 929 L G GIP +Y G++G + +LV+D+LGPSL D+++ G+ + V +AV+ I+++E Sbjct: 126 LAGTPGIPQEYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSVKTVVQVAVQMITLIED 185 Query: 930 LHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFRG 1109 LHA ++ D+KP+NFL+G+PG PD K+ LID G+A ++++ + QH+ Y ++ + G Sbjct: 186 LHAHDLIYRDIKPDNFLIGRPGQPDANKVHLIDFGMAKQYRDPKTKQHIPYREKKSL-SG 244 Query: 1110 TIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDN---KSFLVCKKKMSI 1280 T RY S++ HLGR SRRDD+E++ + + LRG+LPWQG + N K + +KK Sbjct: 245 TARYMSINTHLGREQSRRDDMEAMGHVFFYFLRGQLPWQGLKAPNNKQKYEKIGEKKRLT 304 Query: 1281 SPDLMCCYCAPPFKLFLETVTNMKFDEEPNYP----KLISLFDELIE 1409 + + F +LE V N+ F+E P+Y L+S+ D+L E Sbjct: 305 NVYDLAQGLPIQFGRYLEIVRNLSFEETPDYEGYRMLLLSVLDDLGE 351
>Q06486:KC1D_RAT Casein kinase I isoform delta - Rattus norvegicus (Rat)| Length = 415 Score = 188 bits (478), Expect = 9e-47 Identities = 107/294 (36%), Positives = 170/294 (57%), Gaps = 3/294 (1%) Frame = +3 Query: 543 KVQVGHSPQYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGP 722 +++VG+ +Y++ RK+G G FG +Y+G ++ G E VA+K E +K Sbjct: 2 ELRVGN--RYRLGRKIGSGSFGDIYLGTDIAAGEE--------VAIKLECVKTKHPQLH- 50 Query: 723 PYEWQVYSSLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIA 902 E ++Y + G GIP + + G +GDY V+VM++LGPSL D++N + + V +A Sbjct: 51 -IESKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLA 109 Query: 903 VEAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDY 1082 + IS +E +H+K F+H DVKP+NFL+G +++ID GLA K+++ + QH+ Y Sbjct: 110 DQMISRIEYIHSKNFIHRDVKPDNFLMGL--GKKGNLVYIIDFGLAKKYRDARTHQHIPY 167 Query: 1083 DQRPDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNKS---F 1253 + ++ GT RYAS++ HLG SRRDDLESL Y L++ G LPWQG + K Sbjct: 168 RENKNL-TGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYE 226 Query: 1254 LVCKKKMSISPDLMCCYCAPPFKLFLETVTNMKFDEEPNYPKLISLFDELIEPQ 1415 + +KKMS +++C F +L +++FD++P+Y L LF L Q Sbjct: 227 RISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQ 280
>Q9DC28:KC1D_MOUSE Casein kinase I isoform delta - Mus musculus (Mouse)| Length = 415 Score = 188 bits (478), Expect = 9e-47 Identities = 107/294 (36%), Positives = 170/294 (57%), Gaps = 3/294 (1%) Frame = +3 Query: 543 KVQVGHSPQYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGP 722 +++VG+ +Y++ RK+G G FG +Y+G ++ G E VA+K E +K Sbjct: 2 ELRVGN--RYRLGRKIGSGSFGDIYLGTDIAAGEE--------VAIKLECVKTKHPQLH- 50 Query: 723 PYEWQVYSSLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIA 902 E ++Y + G GIP + + G +GDY V+VM++LGPSL D++N + + V +A Sbjct: 51 -IESKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLA 109 Query: 903 VEAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDY 1082 + IS +E +H+K F+H DVKP+NFL+G +++ID GLA K+++ + QH+ Y Sbjct: 110 DQMISRIEYIHSKNFIHRDVKPDNFLMGL--GKKGNLVYIIDFGLAKKYRDARTHQHIPY 167 Query: 1083 DQRPDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNKS---F 1253 + ++ GT RYAS++ HLG SRRDDLESL Y L++ G LPWQG + K Sbjct: 168 RENKNL-TGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYE 226 Query: 1254 LVCKKKMSISPDLMCCYCAPPFKLFLETVTNMKFDEEPNYPKLISLFDELIEPQ 1415 + +KKMS +++C F +L +++FD++P+Y L LF L Q Sbjct: 227 RISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQ 280
>P48730:KC1D_HUMAN Casein kinase I isoform delta - Homo sapiens (Human)| Length = 415 Score = 188 bits (478), Expect = 9e-47 Identities = 107/294 (36%), Positives = 170/294 (57%), Gaps = 3/294 (1%) Frame = +3 Query: 543 KVQVGHSPQYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGP 722 +++VG+ +Y++ RK+G G FG +Y+G ++ G E VA+K E +K Sbjct: 2 ELRVGN--RYRLGRKIGSGSFGDIYLGTDIAAGEE--------VAIKLECVKTKHPQLH- 50 Query: 723 PYEWQVYSSLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIA 902 E ++Y + G GIP + + G +GDY V+VM++LGPSL D++N + + V +A Sbjct: 51 -IESKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLA 109 Query: 903 VEAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDY 1082 + IS +E +H+K F+H DVKP+NFL+G +++ID GLA K+++ + QH+ Y Sbjct: 110 DQMISRIEYIHSKNFIHRDVKPDNFLMGL--GKKGNLVYIIDFGLAKKYRDARTHQHIPY 167 Query: 1083 DQRPDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNKS---F 1253 + ++ GT RYAS++ HLG SRRDDLESL Y L++ G LPWQG + K Sbjct: 168 RENKNL-TGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYE 226 Query: 1254 LVCKKKMSISPDLMCCYCAPPFKLFLETVTNMKFDEEPNYPKLISLFDELIEPQ 1415 + +KKMS +++C F +L +++FD++P+Y L LF L Q Sbjct: 227 RISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQ 280
>P35508:KC1D_BOVIN Casein kinase I isoform delta - Bos taurus (Bovine)| Length = 415 Score = 188 bits (478), Expect = 9e-47 Identities = 107/294 (36%), Positives = 170/294 (57%), Gaps = 3/294 (1%) Frame = +3 Query: 543 KVQVGHSPQYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGP 722 +++VG+ +Y++ RK+G G FG +Y+G ++ G E VA+K E +K Sbjct: 2 ELRVGN--RYRLGRKIGSGSFGDIYLGTDIAAGEE--------VAIKLECVKTKHPQLH- 50 Query: 723 PYEWQVYSSLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIA 902 E ++Y + G GIP + + G +GDY V+VM++LGPSL D++N + + V +A Sbjct: 51 -IESKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLA 109 Query: 903 VEAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDY 1082 + IS +E +H+K F+H DVKP+NFL+G +++ID GLA K+++ + QH+ Y Sbjct: 110 DQMISRIEYIHSKNFIHRDVKPDNFLMGL--GKKGNLVYIIDFGLAKKYRDARTHQHIPY 167 Query: 1083 DQRPDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNKS---F 1253 + ++ GT RYAS++ HLG SRRDDLESL Y L++ G LPWQG + K Sbjct: 168 RENKNL-TGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYE 226 Query: 1254 LVCKKKMSISPDLMCCYCAPPFKLFLETVTNMKFDEEPNYPKLISLFDELIEPQ 1415 + +KKMS +++C F +L +++FD++P+Y L LF L Q Sbjct: 227 RISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQ 280
>Q9JMK2:KC1E_MOUSE Casein kinase I isoform epsilon - Mus musculus (Mouse)| Length = 416 Score = 187 bits (475), Expect = 2e-46 Identities = 107/294 (36%), Positives = 169/294 (57%), Gaps = 3/294 (1%) Frame = +3 Query: 543 KVQVGHSPQYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGP 722 +++VG+ +Y++ RK+G G FG +Y+G ++ G E VA+K E +K Sbjct: 2 ELRVGN--KYRLGRKIGSGSFGDIYLGANIASGEE--------VAIKLECVKTKHPQLH- 50 Query: 723 PYEWQVYSSLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIA 902 E + Y + G GIP + + G +GDY V+VM++LGPSL D++N + + V +A Sbjct: 51 -IESKFYKMMQGGVGIPSIKWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLA 109 Query: 903 VEAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDY 1082 + IS +E +H+K F+H DVKP+NFL+G +++ID GLA K+++ + QH+ Y Sbjct: 110 DQMISRIEYIHSKNFIHRDVKPDNFLMGL--GKKGNLVYIIDFGLAKKYRDARTHQHIPY 167 Query: 1083 DQRPDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNKS---F 1253 + ++ GT RYAS++ HLG SRRDDLESL Y L++ G LPWQG + K Sbjct: 168 RENKNL-TGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYE 226 Query: 1254 LVCKKKMSISPDLMCCYCAPPFKLFLETVTNMKFDEEPNYPKLISLFDELIEPQ 1415 + +KKMS +++C F +L +++FD++P+Y L LF L Q Sbjct: 227 RISEKKMSTPIEVLCKGYPSEFSTYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQ 280
>P49674:KC1E_HUMAN Casein kinase I isoform epsilon - Homo sapiens (Human)| Length = 416 Score = 187 bits (475), Expect = 2e-46 Identities = 107/294 (36%), Positives = 169/294 (57%), Gaps = 3/294 (1%) Frame = +3 Query: 543 KVQVGHSPQYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGP 722 +++VG+ +Y++ RK+G G FG +Y+G ++ G E VA+K E +K Sbjct: 2 ELRVGN--KYRLGRKIGSGSFGDIYLGANIASGEE--------VAIKLECVKTKHPQLH- 50 Query: 723 PYEWQVYSSLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIA 902 E + Y + G GIP + + G +GDY V+VM++LGPSL D++N + + V +A Sbjct: 51 -IESKFYKMMQGGVGIPSIKWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLA 109 Query: 903 VEAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDY 1082 + IS +E +H+K F+H DVKP+NFL+G +++ID GLA K+++ + QH+ Y Sbjct: 110 DQMISRIEYIHSKNFIHRDVKPDNFLMGL--GKKGNLVYIIDFGLAKKYRDARTHQHIPY 167 Query: 1083 DQRPDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNKS---F 1253 + ++ GT RYAS++ HLG SRRDDLESL Y L++ G LPWQG + K Sbjct: 168 RENKNL-TGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYE 226 Query: 1254 LVCKKKMSISPDLMCCYCAPPFKLFLETVTNMKFDEEPNYPKLISLFDELIEPQ 1415 + +KKMS +++C F +L +++FD++P+Y L LF L Q Sbjct: 227 RISEKKMSTPIEVLCKGYPSEFSTYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQ 280
>P29295:HRR25_YEAST Casein kinase I homolog HRR25 - Saccharomyces cerevisiae (Baker's| yeast) Length = 494 Score = 187 bits (475), Expect = 2e-46 Identities = 103/284 (36%), Positives = 168/284 (59%), Gaps = 5/284 (1%) Frame = +3 Query: 567 QYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYS 746 ++++ RK+G G FG +Y G + G E VA+K E S+ YE +VY Sbjct: 8 KFRIGRKIGSGSFGDIYHGTNLISGEE--------VAIKLESIRSRHPQLD--YESRVYR 57 Query: 747 SLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISILE 926 L+G GIP++ + GR+G+Y +V+D+LGPSL D++N + + V +A++ ++ Sbjct: 58 YLSGGVGIPFIRWFGREGEYNAMVIDLLGPSLEDLFNYCHRRFSFKTVIMLALQMFCRIQ 117 Query: 927 KLHAKGFVHGDVKPENFLL--GQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDI 1100 +H + F+H D+KP+NFL+ G+ GS + +ID GL+ K+++ ++ +H+ Y + + Sbjct: 118 YIHGRSFIHRDIKPDNFLMGVGRRGS----TVHVIDFGLSKKYRDFNTHRHIPYRENKSL 173 Query: 1101 FRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNKS---FLVCKKK 1271 GT RYASV+ HLG SRRDDLESL Y LI+ +G LPWQG + K + +KK Sbjct: 174 -TGTARYASVNTHLGIEQSRRDDLESLGYVLIYFCKGSLPWQGLKATTKKQKYDRIMEKK 232 Query: 1272 MSISPDLMCCYCAPPFKLFLETVTNMKFDEEPNYPKLISLFDEL 1403 +++S + +C F+ ++ N+KFDE+P+Y L LF +L Sbjct: 233 LNVSVETLCSGLPLEFQEYMAYCKNLKFDEKPDYLFLARLFKDL 276
>O74135:CKI3_SCHPO Casein kinase I homolog 3 - Schizosaccharomyces pombe (Fission yeast)| Length = 439 Score = 187 bits (474), Expect = 3e-46 Identities = 102/282 (36%), Positives = 165/282 (58%), Gaps = 3/282 (1%) Frame = +3 Query: 570 YKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYSS 749 Y+V +K+G+G FG ++ G + +ALKFE R S+ E+ Y Sbjct: 15 YRVGKKIGEGSFGMLFQGVNLINNQP--------IALKFESRKSEVPQLRD--EYLTYKL 64 Query: 750 LNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISILEK 929 L G GIP V+Y G++G Y +LVMD+LGPSL D+++ G+ +P VA IA + I+ ++ Sbjct: 65 LMGLPGIPSVYYYGQEGMYNLLVMDLLGPSLEDLFDYCGRRFSPKTVAMIAKQMITRIQS 124 Query: 930 LHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFRG 1109 +H + F++ D+KP+NFL+G PGS E ++ +D G+A ++++ + H Y++ + G Sbjct: 125 VHERHFIYRDIKPDNFLIGFPGSKTENVIYAVDFGMAKQYRDPKTHVHRPYNEHKSL-SG 183 Query: 1110 TIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQG--DNKSFLVCKKKMSIS 1283 T RY S++ HLGR SRRDDLES+ + ++ LRG LPWQG + + + + +K ++ Sbjct: 184 TARYMSINTHLGREQSRRDDLESMGHVFMYFLRGSLPWQGLKAATNKQKYEKIGEKKQVT 243 Query: 1284 PDLMCCYCAP-PFKLFLETVTNMKFDEEPNYPKLISLFDELI 1406 P C P F ++ N+ ++E P+Y L SLFD L+ Sbjct: 244 PLKELCEGYPKEFLQYMIYARNLGYEEAPDYDYLRSLFDSLL 285
>Q5ZLL1:KC1E_CHICK Casein kinase I isoform epsilon - Gallus gallus (Chicken)| Length = 416 Score = 186 bits (473), Expect = 3e-46 Identities = 107/294 (36%), Positives = 169/294 (57%), Gaps = 3/294 (1%) Frame = +3 Query: 543 KVQVGHSPQYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGP 722 +++VG+ +Y++ RK+G G FG +Y+G ++ G E VA+K E +K Sbjct: 2 ELRVGN--KYRLGRKIGSGSFGDIYLGANIATGEE--------VAIKLECVKTKHPQLH- 50 Query: 723 PYEWQVYSSLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIA 902 E + Y + G GIP + + G +GDY V+VM++LGPSL D++N + + V +A Sbjct: 51 -IESKFYKMMQGGVGIPSIKWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLA 109 Query: 903 VEAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDY 1082 + IS +E +H+K F+H DVKP+NFL+G +++ID GLA K+++ + QH+ Y Sbjct: 110 DQMISRIEYIHSKNFIHRDVKPDNFLMGL--GKKGNLVYIIDFGLAKKYRDARTHQHIPY 167 Query: 1083 DQRPDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNKS---F 1253 + ++ GT RYAS++ HLG SRRDDLESL Y L++ G LPWQG + K Sbjct: 168 RENKNL-TGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYE 226 Query: 1254 LVCKKKMSISPDLMCCYCAPPFKLFLETVTNMKFDEEPNYPKLISLFDELIEPQ 1415 + +KKMS +++C F +L +++FD++P+Y L LF L Q Sbjct: 227 RISEKKMSTPIEVLCKGYPSEFSTYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQ 280
>P42158:KC1D_ARATH Casein kinase I isoform delta-like - Arabidopsis thaliana (Mouse-ear| cress) Length = 450 Score = 185 bits (469), Expect = 1e-45 Identities = 102/282 (36%), Positives = 170/282 (60%), Gaps = 3/282 (1%) Frame = +3 Query: 567 QYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYS 746 ++++ RK+G G FG++Y+G + E +A+K E+ +K YE ++Y Sbjct: 8 KFRLGRKIGSGSFGEIYLGTNIHTNEE--------LAIKLENVKTKHPQL--LYESKLYR 57 Query: 747 SLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISILE 926 L G G+P V + G +GDY VLVMD+LGPSL D++N + ++ V +A + I+ +E Sbjct: 58 ILQGGTGVPNVKWFGVEGDYNVLVMDLLGPSLEDLFNFCSRKLSLKSVLMLADQMINRVE 117 Query: 927 KLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFR 1106 H+K F+H D+KP+NFL+G ++ +++ID GLA K++++++ QH+ Y + ++ Sbjct: 118 FFHSKSFLHRDLKPDNFLMGLGRRANQ--VYIIDFGLAKKYRDSTTHQHIPYRENKNL-T 174 Query: 1107 GTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNKS---FLVCKKKMS 1277 GT RYAS++ HLG SRRDDLESL Y L++ L+G LPWQG + K + +KK+S Sbjct: 175 GTARYASMNTHLGIEQSRRDDLESLGYILMYFLKGSLPWQGLKAGTKKQKYERISEKKVS 234 Query: 1278 ISPDLMCCYCAPPFKLFLETVTNMKFDEEPNYPKLISLFDEL 1403 S + +C F + +++FD++P+Y L +F +L Sbjct: 235 TSIEALCRGYPSEFASYFHYCRSLRFDDKPDYAYLKRIFRDL 276
>P54367:KC1A_DROME Casein kinase I isoform alpha - Drosophila melanogaster (Fruit fly)| Length = 337 Score = 185 bits (469), Expect = 1e-45 Identities = 104/279 (37%), Positives = 163/279 (58%), Gaps = 3/279 (1%) Frame = +3 Query: 567 QYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYS 746 +Y+V RK+G G FG +Y+G + G E VA+K E +++ YE ++Y Sbjct: 19 KYRVIRKIGSGSFGDIYLGMSIQSGEE--------VAIKMESAHARHPQL--LYEAKLYR 68 Query: 747 SLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISILE 926 L+G G P + + G++ ++ LVMD+LGPSL D++N + T V + + I LE Sbjct: 69 ILSGGVGFPRIRHHGKEKNFNTLVMDLLGPSLEDLFNFCTRHFTIKTVLMLVDQMIGRLE 128 Query: 927 KLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFR 1106 +H K F+H D+KP+NFL+G KLFLID GLA K+++ + H+ Y + ++ Sbjct: 129 YIHLKCFIHRDIKPDNFLMGI--GRHCNKLFLIDFGLAKKFRDPHTRHHIVYREDKNL-T 185 Query: 1107 GTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNKS---FLVCKKKMS 1277 GT RYAS++AHLG SRRDD+ESL Y +++ RG LPWQG + + K + +KKMS Sbjct: 186 GTARYASINAHLGIEQSRRDDMESLGYVMMYFNRGVLPWQGMKANTKQQKYEKISEKKMS 245 Query: 1278 ISPDLMCCYCAPPFKLFLETVTNMKFDEEPNYPKLISLF 1394 +++C F ++L +++F+E+P+Y L LF Sbjct: 246 TPIEVLCKGSPAEFSMYLNYCRSLRFEEQPDYMYLRQLF 284
>P40233:CKI1_SCHPO Casein kinase I homolog 1 - Schizosaccharomyces pombe (Fission yeast)| Length = 446 Score = 184 bits (467), Expect = 2e-45 Identities = 98/283 (34%), Positives = 162/283 (57%), Gaps = 3/283 (1%) Frame = +3 Query: 570 YKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYSS 749 YKV R++G+G FG ++ G + + VA+KFE R S E++ Y Sbjct: 12 YKVGRRIGEGSFGVIFEGTNLLNNQQ--------VAIKFEPRRSDAPQLRD--EYRTYKL 61 Query: 750 LNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISILEK 929 L GC GIP V+Y G++G + +LV+D+LGPSL D+ + G+ + VA A + ++ ++ Sbjct: 62 LAGCTGIPNVYYFGQEGLHNILVIDLLGPSLEDLLDLCGRKFSVKTVAMAAKQMLARVQS 121 Query: 930 LHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFRG 1109 +H K V+ D+KP+NFL+G+P S + ++++D G+ +++ + QH+ Y ++ ++ G Sbjct: 122 IHEKSLVYRDIKPDNFLIGRPNSKNANMIYVVDFGMVKFYRDPVTKQHIPYREKKNL-SG 180 Query: 1110 TIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQ---GDNKSFLVCKKKMSI 1280 T RY S++ HLGR SRRDDLE+L + ++ LRG LPWQG + K + +KK S Sbjct: 181 TARYMSINTHLGREQSRRDDLEALGHVFMYFLRGSLPWQGLKAATNKQKYERIGEKKQST 240 Query: 1281 SPDLMCCYCAPPFKLFLETVTNMKFDEEPNYPKLISLFDELIE 1409 +C F ++ N+ FD P+Y L LF +++E Sbjct: 241 PLRELCAGFPEEFYKYMHYARNLAFDATPDYDYLQGLFSKVLE 283
>P40230:RAG8_KLULA Casein kinase I homolog RAG8 - Kluyveromyces lactis (Yeast) (Candida| sphaerica) Length = 536 Score = 184 bits (466), Expect = 2e-45 Identities = 101/285 (35%), Positives = 166/285 (58%), Gaps = 7/285 (2%) Frame = +3 Query: 570 YKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYSS 749 YK+ +K+G+G FG ++ G + VA+KFE R + E++ Y Sbjct: 77 YKIGKKIGEGSFGVLFEGVNMINNVP--------VAIKFEPRKTDAPQLKD--EYRTYKI 126 Query: 750 LNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISILEK 929 L+G GIP +Y G++G + +LV+D+LGPSL D+++ G+ + V +A++ I+++E+ Sbjct: 127 LSGSEGIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEE 186 Query: 930 LHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFRG 1109 LH ++ D+KP+NFL+G+P PD + LID G+A +++ + QH+ Y ++ + G Sbjct: 187 LHDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSL-SG 245 Query: 1110 TIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDN---KSFLVCKKKMSI 1280 T RY S++ HLGR SRRDD+E+L + + LRG+LPWQG + N K + +KK S Sbjct: 246 TARYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRST 305 Query: 1281 SPDLMCCYCAPPFKLFLETVTNMKFDEEPNY----PKLISLFDEL 1403 + + F +LE V N+ F+E P+Y L+S+ DEL Sbjct: 306 NVYDLSQGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDEL 350
>Q6QNL9:KC1_EIMTE Casein kinase I - Eimeria tenella| Length = 335 Score = 181 bits (458), Expect = 2e-44 Identities = 100/282 (35%), Positives = 166/282 (58%), Gaps = 3/282 (1%) Frame = +3 Query: 567 QYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYS 746 +Y++ RK+G G FG +Y+G +S G E VA+K E S+ YE ++Y Sbjct: 8 KYRLGRKIGSGSFGDIYLGTNISTGDE--------VAIKLESVRSRHPQL--IYESKLYK 57 Query: 747 SLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISILE 926 L G GIP +++ G +GDY V+++++LGPSL D+++ + ++ V +A + ++ +E Sbjct: 58 ILTGGIGIPTLYWYGIEGDYNVMIIELLGPSLEDLFSICNRKLSLKTVLMLADQMLNRIE 117 Query: 927 KLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFR 1106 +H++ F+H D+KP+NFL+G+ +F ID GLA K+++ + H+ Y + ++ Sbjct: 118 FVHSRHFIHRDIKPDNFLIGR--GKKMSIVFAIDFGLAKKYRDPRTQSHIPYREGKNL-T 174 Query: 1107 GTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNKS---FLVCKKKMS 1277 GT RYASV+ HLG SRRDDLE+L Y L++ RG LPWQG + K + +KKMS Sbjct: 175 GTARYASVNTHLGIEQSRRDDLEALGYVLMYFNRGSLPWQGLKATTKKDKYDKIMEKKMS 234 Query: 1278 ISPDLMCCYCAPPFKLFLETVTNMKFDEEPNYPKLISLFDEL 1403 +++C F +L +++F++ P+Y L LF +L Sbjct: 235 TPIEVLCKQFPFEFITYLNYCRSLRFEDRPDYSYLRRLFKDL 276
>P35507:KC1B_BOVIN Casein kinase I isoform beta - Bos taurus (Bovine)| Length = 336 Score = 180 bits (457), Expect = 2e-44 Identities = 107/293 (36%), Positives = 166/293 (56%), Gaps = 3/293 (1%) Frame = +3 Query: 525 ASPVPEKVQVGHSPQYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSK 704 AS K V +YK+ R++G G FG VY+ ++ + VA+K E N++ Sbjct: 2 ASSSRPKTDVLVGGRYKLVREIGFGSFGHVYLAIDLTNHEQ--------VAVKLESENTR 53 Query: 705 GCNYGPPYEWQVYSSLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPS 884 +E ++Y+ L G GIP + + G++ DY VLVMD+LGPSL D++N + + Sbjct: 54 QPRL--LHEKELYNFLQGGVGIPQIRWYGQETDYNVLVMDLLGPSLEDLFNFCSRRFSMK 111 Query: 885 MVACIAVEAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSS 1064 V +A + IS +E +H++ +H D+KP+NFL+G P KKLFL+D GLA K+++ + Sbjct: 112 TVLMLADQMISRIEYVHSRNLIHRDIKPDNFLMGT--GPQWKKLFLVDFGLAKKYRDNRT 169 Query: 1065 GQHVDYDQRPDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQG-- 1238 GQH+ + + F GT AS+ AHLG SRRDD+ES+ Y L++ RG LPWQG + Sbjct: 170 GQHIPH-RSGKSFIGTPFCASISAHLGIEQSRRDDMESIGYVLMYFNRGSLPWQGLKAAT 228 Query: 1239 -DNKSFLVCKKKMSISPDLMCCYCAPPFKLFLETVTNMKFDEEPNYPKLISLF 1394 K + + KM+ D++C F ++L+ + F+E P+Y L LF Sbjct: 229 LKQKCEKISEMKMTTPVDVLCKGFPIEFAMYLKYCLRLSFEEAPDYRYLRQLF 281
>O76324:DCO_DROME Discs overgrown protein kinase - Drosophila melanogaster (Fruit fly)| Length = 440 Score = 179 bits (453), Expect = 7e-44 Identities = 105/290 (36%), Positives = 167/290 (57%), Gaps = 3/290 (1%) Frame = +3 Query: 543 KVQVGHSPQYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGP 722 +++VG+ +Y++ RK+G G FG +Y+G ++ G E VA+K E +K Sbjct: 2 ELRVGN--KYRLGRKIGSGSFGDIYLGTTINTGEE--------VAIKLECIRTKHPQLH- 50 Query: 723 PYEWQVYSSLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIA 902 E + Y ++ G GIP + + G +GDY V+VM++LGPSL D++N + + V +A Sbjct: 51 -IESKFYKTMQGGIGIPRIIWCGSEGDYNVMVMELLGPSLEDLFNFCSRRFSLKTVLLLA 109 Query: 903 VEAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDY 1082 + IS ++ +H++ F+H D+KP+NFL+G +++ID GLA K+++ S +H+ Y Sbjct: 110 DQMISRIDYIHSRDFIHRDIKPDNFLMGL--GKKGNLVYIIDFGLAKKFRDARSLKHIPY 167 Query: 1083 DQRPDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNKS---F 1253 + ++ GT RYAS++ HLG SRRDDLESL Y L++ G LPWQG + NK Sbjct: 168 RENKNL-TGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGALPWQGLKAANKRQKYE 226 Query: 1254 LVCKKKMSISPDLMCCYCAPPFKLFLETVTNMKFDEEPNYPKLISLFDEL 1403 + +KK+S S ++C F +L M FD+ P+Y L LF L Sbjct: 227 RISEKKLSTSIVVLCKGFPSEFVNYLNFCRQMHFDQRPDYCHLRKLFRNL 276
>P40236:HHP2_SCHPO Casein kinase I homolog hhp2 - Schizosaccharomyces pombe (Fission| yeast) Length = 400 Score = 178 bits (452), Expect = 9e-44 Identities = 102/290 (35%), Positives = 162/290 (55%), Gaps = 3/290 (1%) Frame = +3 Query: 546 VQVGHSPQYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPP 725 +++G+ +Y++ RK+G G FGQ+Y+G G + VA+K E ++ ++ Sbjct: 6 IKIGN--KYRIGRKIGSGSFGQIYLGLNTVNGEQ--------VAVKLEPLKAR--HHQLE 53 Query: 726 YEWQVYSSLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAV 905 YE++VY+ L G GIP + + G Y +VMD+LGPSL D++ G+ T V +A Sbjct: 54 YEFRVYNILKGNIGIPTIRWFGVTNSYNAMVMDLLGPSLEDLFCYCGRKFTLKTVLLLAD 113 Query: 906 EAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYD 1085 + IS +E +H+K F+H D+KP+NFL+ + +ID GLA K+++ + H+ Y Sbjct: 114 QLISRIEYVHSKSFLHRDIKPDNFLM----KKHSNVVTMIDFGLAKKYRDFKTHVHIPYR 169 Query: 1086 QRPDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNKS---FL 1256 ++ GT RYAS++ H+G SRRDDLESL Y L++ RG LPWQG Q D K Sbjct: 170 DNKNL-TGTARYASINTHIGIEQSRRDDLESLGYVLLYFCRGSLPWQGLQADTKEQKYQR 228 Query: 1257 VCKKKMSISPDLMCCYCAPPFKLFLETVTNMKFDEEPNYPKLISLFDELI 1406 + K+ +++C F ++ + F E+PNY L LF +L+ Sbjct: 229 IRDTKIGTPLEVLCKGLPEEFITYMCYTRQLSFTEKPNYAYLRKLFRDLL 278
>Q8IHZ9:KC1_PLAF7 Casein kinase I - Plasmodium falciparum (isolate 3D7)| Length = 323 Score = 176 bits (445), Expect = 6e-43 Identities = 97/282 (34%), Positives = 163/282 (57%), Gaps = 3/282 (1%) Frame = +3 Query: 567 QYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYS 746 +Y + +KLG G FG +YV + + E A+K E SK YE ++Y Sbjct: 8 KYALGKKLGSGSFGDIYVAKDIV--------TMEEFAVKLESTRSKHPQL--LYESKLYK 57 Query: 747 SLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISILE 926 L G G+P V++ G +GD+ ++V+D+LGPSL D++ + + V A + ++ +E Sbjct: 58 ILGGGIGVPKVYWYGIEGDFTIMVLDLLGPSLEDLFTLCNRKFSLKTVLMTADQMLNRIE 117 Query: 927 KLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFR 1106 +H+K F+H D+KP+NFL+G+ + +ID GLA K++++ S H+ Y + ++ Sbjct: 118 YVHSKNFIHRDIKPDNFLIGR--GKKVTLIHIIDFGLAKKYRDSRSHTHIPYKEGKNL-T 174 Query: 1107 GTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQG---DNKSFLVCKKKMS 1277 GT RYAS++ HLG SRRDD+E+L Y L++ LRG LPWQG + +K + +KK+S Sbjct: 175 GTARYASINTHLGIEQSRRDDIEALGYVLMYFLRGSLPWQGLKAISKKDKYDKIMEKKIS 234 Query: 1278 ISPDLMCCYCAPPFKLFLETVTNMKFDEEPNYPKLISLFDEL 1403 S +++C + F +L +++F++ P+Y L L +L Sbjct: 235 TSVEVLCRNASFEFVTYLNYCRSLRFEDRPDYTYLRRLLKDL 276
>Q7RBX5:KC1_PLAYO Casein kinase I - Plasmodium yoelii yoelii| Length = 323 Score = 175 bits (444), Expect = 8e-43 Identities = 97/282 (34%), Positives = 163/282 (57%), Gaps = 3/282 (1%) Frame = +3 Query: 567 QYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYS 746 +Y + +KLG G FG +YV + + E A+K E SK YE ++Y Sbjct: 8 KYALGKKLGSGSFGDIYVAKDIV--------TMEEFAVKLESTRSKHPQL--LYESKLYK 57 Query: 747 SLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISILE 926 L G G+P V++ G +GD+ ++V+D+LGPSL D++ + + V A + ++ +E Sbjct: 58 ILGGGIGVPKVYWYGIEGDFTIMVLDLLGPSLEDLFTLCNRKFSLKTVLMTADQMLNRIE 117 Query: 927 KLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFR 1106 +H+K F+H D+KP+NFL+G+ + +ID GLA K++++ S H+ Y + ++ Sbjct: 118 YVHSKNFIHRDIKPDNFLIGR--GKKVTLIHIIDFGLAKKYRDSRSHTHIPYKEGKNL-T 174 Query: 1107 GTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQG---DNKSFLVCKKKMS 1277 GT RYAS++ HLG SRRDD+E+L Y L++ LRG LPWQG + +K + +KK+S Sbjct: 175 GTARYASINTHLGIEQSRRDDIEALGYVLMYFLRGSLPWQGLKAISKKDKYDKIMEKKIS 234 Query: 1278 ISPDLMCCYCAPPFKLFLETVTNMKFDEEPNYPKLISLFDEL 1403 S +++C + F +L +++F++ P+Y L L +L Sbjct: 235 TSVEVLCRNTSFEFVTYLNYCRSLRFEDRPDYTYLRRLLKDL 276
>Q9Y6M4:KC1G3_HUMAN Casein kinase I isoform gamma-3 - Homo sapiens (Human)| Length = 447 Score = 175 bits (444), Expect = 8e-43 Identities = 104/317 (32%), Positives = 172/317 (54%), Gaps = 2/317 (0%) Frame = +3 Query: 465 DKVVKMDGVSPEKIGGGEDDASPVPEKVQVGHSPQYKVERKLGKGGFGQVYVGRRVSGGT 644 D++ + G S G +S V + VG P ++V +K+G G FG++ +G+ + Sbjct: 13 DRMARPSGRSGHNTRGTGSSSSGV---LMVG--PNFRVGKKIGCGNFGELRLGKNLYTNE 67 Query: 645 ERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYSSLNGCYGIPWVHYKGRQGDYYVLVMD 824 VA+K E S+ E++ Y L GIP V+Y G G Y +V++ Sbjct: 68 Y--------VAIKLEPMKSRAPQLH--LEYRFYKQLGSGDGIPQVYYFGPCGKYNAMVLE 117 Query: 825 ILGPSLWDVWNSLGQTMTPSMVACIAVEAISILEKLHAKGFVHGDVKPENFLLGQPGSPD 1004 +LGPSL D+++ +T + V IA++ IS +E +H+K ++ DVKPENFL+G+PG+ Sbjct: 118 LLGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNKT 177 Query: 1005 EKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFRGTIRYASVHAHLGRTGSRRDDLESLA 1184 ++ + +ID GLA ++ + + +H+ Y + + GT RY S++ HLG+ SRRDDLE+L Sbjct: 178 QQVIHIIDFGLAKEYIDPETKKHIPYREHKSL-TGTARYMSINTHLGKEQSRRDDLEALG 236 Query: 1185 YTLIFLLRGRLPWQGYQGD--NKSFLVCKKKMSISPDLMCCYCAPPFKLFLETVTNMKFD 1358 + ++ LRG LPWQG + D + + +P + C P +L V + F Sbjct: 237 HMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEMATYLRYVRRLDFF 296 Query: 1359 EEPNYPKLISLFDELIE 1409 E+P+Y L LF +L + Sbjct: 297 EKPDYDYLRKLFTDLFD 313
>P39962:KC13_YEAST Casein kinase I homolog 3 - Saccharomyces cerevisiae (Baker's yeast)| Length = 524 Score = 175 bits (443), Expect = 1e-42 Identities = 102/315 (32%), Positives = 165/315 (52%), Gaps = 30/315 (9%) Frame = +3 Query: 570 YKVERKLGKGGFGQVYVGRRVSGGTE-RTGPDAYE--------VALKFEHRNSKGCNYGP 722 Y V K+G+G FG ++ G + + +TG VA+KFE R+S Sbjct: 14 YAVGPKIGEGSFGVIFEGENILHSCQAQTGSKRDSSIIMANEPVAIKFEPRHSDAPQLRD 73 Query: 723 PYEWQVYSSLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIA 902 E++ Y LNGC GIP +Y G++G + +L++D+LGPSL D++ G+ + +A Sbjct: 74 --EFRAYRILNGCVGIPHAYYFGQEGMHNILIIDLLGPSLEDLFEWCGRKFSVKTTCMVA 131 Query: 903 VEAISILEKLHAKGFVHGDVKPENFLLGQ----------------PGSPDEKKLFLIDLG 1034 + I + +H ++ D+KP+NFL+ Q + D ++++D G Sbjct: 132 KQMIDRVRAIHDHDLIYRDIKPDNFLISQYQRISPEGKVIKSCASSSNNDPNLIYMVDFG 191 Query: 1035 LASKWKETSSGQHVDYDQRPDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGR 1214 +A ++++ + QH+ Y +R + GT RY S++ H GR SRRDDLESL + + LRG Sbjct: 192 MAKQYRDPRTKQHIPYRERKSL-SGTARYMSINTHFGREQSRRDDLESLGHVFFYFLRGS 250 Query: 1215 LPWQGYQGDNKSFLVCK---KKMSISPDLMCCYCAPP--FKLFLETVTNMKFDEEPNYPK 1379 LPWQG + N K K ++PD + A P F +L+ ++KFDE+P+Y Sbjct: 251 LPWQGLKAPNNKLKYEKIGMTKQKLNPDDLLLNNAIPYQFATYLKYARSLKFDEDPDYDY 310 Query: 1380 LISLFDELIEPQHLR 1424 LISL D+ + L+ Sbjct: 311 LISLMDDALRLNDLK 325
>Q62763:KC1G3_RAT Casein kinase I isoform gamma-3 - Rattus norvegicus (Rat)| Length = 448 Score = 172 bits (437), Expect = 5e-42 Identities = 103/318 (32%), Positives = 173/318 (54%), Gaps = 3/318 (0%) Frame = +3 Query: 465 DKVVKMDGVSPEKIGGGEDDASPVPEKVQVGHSPQYKVERKLGKGGFGQVYVGRRVSGGT 644 D++ + G S G +S V + VG P ++V +K+G G FG++ +G+ + Sbjct: 13 DRMARPSGRSGHSTRGTGSSSSGV---LMVG--PNFRVGKKIGCGNFGELRLGKNLYTNE 67 Query: 645 ERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYSSLNGCYGIPWVHYKGRQGDYYVLVMD 824 VA+K E S+ E++ Y L GIP V+Y G G Y +V++ Sbjct: 68 Y--------VAIKLEPMKSRAPQLH--LEYRFYKQLGSGDGIPQVYYFGPCGKYNAMVLE 117 Query: 825 ILGPSLWDVWNSLGQTMTPSMVACIAVEAISILEKLHAKGFVHGDVKPENFLLGQPGSPD 1004 +LGPSL D+++ +T + V IA++ IS +E +H+K ++ DVKPENFL+G+PG+ Sbjct: 118 LLGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNKA 177 Query: 1005 EKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFRGTIRYASVHAHLGRTGSRRDDLESLA 1184 ++ + +ID GLA ++ + + +H+ Y + + GT RY S++ HLG+ SRRDDLE+L Sbjct: 178 QQVIHIIDFGLAKEYIDPETKKHIPYREHKSL-TGTARYMSINTHLGKEQSRRDDLEALG 236 Query: 1185 YTLIFLLRGRLPWQGYQGD---NKSFLVCKKKMSISPDLMCCYCAPPFKLFLETVTNMKF 1355 + ++ LRG LPWQG + D + + K + +++C +L V + F Sbjct: 237 HMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEEMATYLRYVRRLDF 296 Query: 1356 DEEPNYPKLISLFDELIE 1409 E+P+Y L LF +L + Sbjct: 297 FEKPDYDYLRKLFTDLFD 314
>Q62762:KC1G2_RAT Casein kinase I isoform gamma-2 - Rattus norvegicus (Rat)| Length = 415 Score = 171 bits (434), Expect = 1e-41 Identities = 95/285 (33%), Positives = 159/285 (55%), Gaps = 3/285 (1%) Frame = +3 Query: 564 PQYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVY 743 P ++V +K+G G FG++ +G+ + VA+K E S+ E++ Y Sbjct: 44 PNFRVGKKIGCGNFGELRLGKNLYTNEY--------VAIKLEPIKSRAPQLH--LEYRFY 93 Query: 744 SSLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISIL 923 L+ G+P V+Y G G Y +V+++LGPSL D+++ +T T V IA++ I+ + Sbjct: 94 KQLSTTEGVPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLITRM 153 Query: 924 EKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIF 1103 E +H K ++ DVKPENFL+G+PGS + + +ID GLA ++ + + +H+ Y + + Sbjct: 154 EYVHTKSLIYRDVKPENFLVGRPGSKRQHSIHIIDFGLAKEYIDPETKKHIPYREHKSL- 212 Query: 1104 RGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGD---NKSFLVCKKKM 1274 GT RY S++ HLG+ SRRDDLE+L + ++ LRG LPWQG + D + + K Sbjct: 213 TGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKR 272 Query: 1275 SISPDLMCCYCAPPFKLFLETVTNMKFDEEPNYPKLISLFDELIE 1409 + +++C +L V + F E+P+Y L LF +L + Sbjct: 273 ATPIEVLCESFPEEMATYLRYVRRLDFFEKPDYDYLRKLFTDLFD 317
>Q8BVP5:KC1G2_MOUSE Casein kinase I isoform gamma-2 - Mus musculus (Mouse)| Length = 415 Score = 171 bits (434), Expect = 1e-41 Identities = 95/285 (33%), Positives = 159/285 (55%), Gaps = 3/285 (1%) Frame = +3 Query: 564 PQYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVY 743 P ++V +K+G G FG++ +G+ + VA+K E S+ E++ Y Sbjct: 44 PNFRVGKKIGCGNFGELRLGKNLYTNEY--------VAIKLEPIKSRAPQLH--LEYRFY 93 Query: 744 SSLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISIL 923 L+ G+P V+Y G G Y +V+++LGPSL D+++ +T T V IA++ I+ + Sbjct: 94 KQLSTTEGVPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLITRM 153 Query: 924 EKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIF 1103 E +H K ++ DVKPENFL+G+PGS + + +ID GLA ++ + + +H+ Y + + Sbjct: 154 EYVHTKSLIYRDVKPENFLVGRPGSKRQHSIHIIDFGLAKEYIDPETKKHIPYREHKSL- 212 Query: 1104 RGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGD---NKSFLVCKKKM 1274 GT RY S++ HLG+ SRRDDLE+L + ++ LRG LPWQG + D + + K Sbjct: 213 TGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKR 272 Query: 1275 SISPDLMCCYCAPPFKLFLETVTNMKFDEEPNYPKLISLFDELIE 1409 + +++C +L V + F E+P+Y L LF +L + Sbjct: 273 ATPIEVLCESFPEEMATYLRYVRRLDFFEKPDYDYLRKLFTDLFD 317
>O15726:KC1_PLAF4 Casein kinase I - Plasmodium falciparum (isolate Dd2)| Length = 324 Score = 171 bits (432), Expect = 2e-41 Identities = 96/282 (34%), Positives = 161/282 (57%), Gaps = 3/282 (1%) Frame = +3 Query: 567 QYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYS 746 +Y + +KLG G FG +YV + + E A+K E SK YE ++Y Sbjct: 8 KYALGKKLGSGSFGDIYVAKDIV--------TMEEFAVKLESTRSKHPQL--LYESKLYK 57 Query: 747 SLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISILE 926 L G G+P V++ G +GD+ ++V+D+LGPSL D++ + + V A + ++ +E Sbjct: 58 ILGGGIGVPKVYWYGIEGDFTIMVLDLLGPSLEDLFTLCNRKFSLKTVRMTADQMLNRIE 117 Query: 927 KLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFR 1106 +H+K F+H D+KP+NFL+G+ + +ID GLA K++++ S Y + ++ Sbjct: 118 YVHSKNFIHRDIKPDNFLIGR--GKKVTLIHIIDFGLAKKYRDSRSHTSYPYKEGKNL-T 174 Query: 1107 GTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQG---DNKSFLVCKKKMS 1277 GT RYAS++ HLG SRRDD+E+L Y L++ LRG LPWQG + +K + +KK+S Sbjct: 175 GTARYASINTHLGIEQSRRDDIEALGYVLMYFLRGSLPWQGLKAISKKDKYDKIMEKKIS 234 Query: 1278 ISPDLMCCYCAPPFKLFLETVTNMKFDEEPNYPKLISLFDEL 1403 S +++C + F +L +++F++ P+Y L L +L Sbjct: 235 TSVEVLCRNASFEFVTYLNYCRSLRFEDRPDYTYLRRLLKDL 276
>P78368:KC1G2_HUMAN Casein kinase I isoform gamma-2 - Homo sapiens (Human)| Length = 415 Score = 171 bits (432), Expect = 2e-41 Identities = 94/285 (32%), Positives = 159/285 (55%), Gaps = 3/285 (1%) Frame = +3 Query: 564 PQYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVY 743 P ++V +K+G G FG++ +G+ + VA+K E S+ E++ Y Sbjct: 44 PNFRVGKKIGCGNFGELRLGKNLYTNEY--------VAIKLEPIKSRAPQLH--LEYRFY 93 Query: 744 SSLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISIL 923 L+ G+P V+Y G G Y +V+++LGPSL D+++ +T T V IA++ I+ + Sbjct: 94 KQLSATEGVPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLITRM 153 Query: 924 EKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIF 1103 E +H K ++ DVKPENFL+G+PG+ + + +ID GLA ++ + + +H+ Y + + Sbjct: 154 EYVHTKSLIYRDVKPENFLVGRPGTKRQHAIHIIDFGLAKEYIDPETKKHIPYREHKSL- 212 Query: 1104 RGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGD---NKSFLVCKKKM 1274 GT RY S++ HLG+ SRRDDLE+L + ++ LRG LPWQG + D + + K Sbjct: 213 TGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKR 272 Query: 1275 SISPDLMCCYCAPPFKLFLETVTNMKFDEEPNYPKLISLFDELIE 1409 + +++C +L V + F E+P+Y L LF +L + Sbjct: 273 ATPIEVLCENFPEEMATYLRYVRRLDFFEKPDYDYLRKLFTDLFD 317
>Q20471:KIN20_CAEEL Casein kinase I isoform delta - Caenorhabditis elegans| Length = 497 Score = 170 bits (430), Expect = 3e-41 Identities = 101/294 (34%), Positives = 168/294 (57%), Gaps = 3/294 (1%) Frame = +3 Query: 543 KVQVGHSPQYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGP 722 +++VG+ ++++ RK+G G FG +Y+G+ + E VA+K E SK Sbjct: 184 ELRVGN--RFRLGRKIGSGSFGDIYLGQNIQTNEE--------VAVKLECVKSKHPQLH- 232 Query: 723 PYEWQVYSSLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIA 902 E ++Y + G GIP + + G++GDY V+VM++LGPSL D++N + + V +A Sbjct: 233 -IESRLYRIMLGGIGIPEIRWCGQEGDYNVMVMELLGPSLEDLFNFCQRKFSLKTVLLLA 291 Query: 903 VEAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDY 1082 + +S +E +H + ++H D+KP+NFL+G +++ID GLA ++++ S QH+ Y Sbjct: 292 DQMLSRVEFIHCRDYIHRDIKPDNFLMGL--GKRGNLVYIIDFGLAKRYRD-SKHQHIAY 348 Query: 1083 DQRPDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQG---DNKSF 1253 + ++ GT RYAS++ H G SRRDD+ESL Y ++ RG LPWQG + K Sbjct: 349 RENKNL-TGTARYASINTHRGIEQSRRDDIESLGYVFMYFNRGTLPWQGLKAVTKRQKYE 407 Query: 1254 LVCKKKMSISPDLMCCYCAPPFKLFLETVTNMKFDEEPNYPKLISLFDELIEPQ 1415 L+ +KK+S D +C F +L ++ F+E+P+Y L +LF L Q Sbjct: 408 LISEKKISTRVDDLCAGYPEAFAQYLNYCRSLGFEEQPDYGYLRNLFRTLFHRQ 461
>Q62761:KC1G1_RAT Casein kinase I isoform gamma-1 - Rattus norvegicus (Rat)| Length = 390 Score = 167 bits (422), Expect = 3e-40 Identities = 96/286 (33%), Positives = 158/286 (55%), Gaps = 4/286 (1%) Frame = +3 Query: 564 PQYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVY 743 P ++V +K+G G FG++ +G+ + VA+K E S+ E++ Y Sbjct: 42 PNFRVGKKIGCGNFGELRLGKNLYTNEY--------VAIKLEPIKSRAPQLH--LEYRFY 91 Query: 744 SSLNGC-YGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISI 920 L G+P V+Y G G Y +V+++LGPSL D+++ +T T V IA++ +S Sbjct: 92 KQLGSAGEGLPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLLSR 151 Query: 921 LEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDI 1100 +E +H+K ++ DVKPENFL+G+ G+ E + +ID GLA ++ + + +H+ Y + + Sbjct: 152 MEYVHSKNLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEYIDPETKKHIPYREHKSL 211 Query: 1101 FRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGD---NKSFLVCKKK 1271 GT RY S++ HLG+ SRRDDLE+L + ++ LRG LPWQG + D + + K Sbjct: 212 -TGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTK 270 Query: 1272 MSISPDLMCCYCAPPFKLFLETVTNMKFDEEPNYPKLISLFDELIE 1409 S + +C +L V + F E+P+Y L +LF +L E Sbjct: 271 RSTPIEALCENFPEEMMTYLRYVRRLDFFEKPDYEYLRNLFTDLFE 316
>Q8BTH8:KC1G1_MOUSE Casein kinase I isoform gamma-1 - Mus musculus (Mouse)| Length = 459 Score = 166 bits (420), Expect = 5e-40 Identities = 95/286 (33%), Positives = 158/286 (55%), Gaps = 4/286 (1%) Frame = +3 Query: 564 PQYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVY 743 P ++V +K+G G FG++ +G+ + VA+K E S+ E++ Y Sbjct: 42 PNFRVGKKIGCGNFGELRLGKNLYTNEY--------VAIKLEPIKSRAPQLH--LEYRFY 91 Query: 744 SSLNGC-YGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISI 920 L G+P V+Y G G Y +V+++LGPSL D+++ +T T V IA++ +S Sbjct: 92 KQLGSAGEGLPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLLSR 151 Query: 921 LEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDI 1100 +E +H+K ++ DVKPENFL+G+ G+ E + +ID GLA ++ + + +H+ Y + + Sbjct: 152 MEYVHSKNLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEYVDPETKKHIPYREHKSL 211 Query: 1101 FRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGD---NKSFLVCKKK 1271 GT RY S++ HLG+ SRRDDLE+L + ++ LRG LPWQG + D + + K Sbjct: 212 -TGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTK 270 Query: 1272 MSISPDLMCCYCAPPFKLFLETVTNMKFDEEPNYPKLISLFDELIE 1409 + + +C +L V + F E+P+Y L +LF +L E Sbjct: 271 RNTPIEALCENFPEEMATYLRYVRRLDFFEKPDYEYLRTLFTDLFE 316
>Q9HCP0:KC1G1_HUMAN Casein kinase I isoform gamma-1 - Homo sapiens (Human)| Length = 422 Score = 166 bits (419), Expect = 6e-40 Identities = 95/286 (33%), Positives = 158/286 (55%), Gaps = 4/286 (1%) Frame = +3 Query: 564 PQYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVY 743 P ++V +K+G G FG++ +G+ + VA+K E S+ E++ Y Sbjct: 42 PNFRVGKKIGCGNFGELRLGKNLYTNEY--------VAIKLEPIKSRAPQLH--LEYRFY 91 Query: 744 SSLNGC-YGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISI 920 L G+P V+Y G G Y +V+++LGPSL D+++ +T T V IA++ +S Sbjct: 92 KQLGSAGEGLPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLLSR 151 Query: 921 LEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDI 1100 +E +H+K ++ DVKPENFL+G+ G+ E + +ID GLA ++ + + +H+ Y + + Sbjct: 152 MEYVHSKNLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEYIDPETKKHIPYREHKSL 211 Query: 1101 FRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGD---NKSFLVCKKK 1271 GT RY S++ HLG+ SRRDDLE+L + ++ LRG LPWQG + D + + K Sbjct: 212 -TGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTK 270 Query: 1272 MSISPDLMCCYCAPPFKLFLETVTNMKFDEEPNYPKLISLFDELIE 1409 + + +C +L V + F E+P+Y L +LF +L E Sbjct: 271 RNTPIEALCENFPEEMATYLRYVRRLDFFEKPDYEYLRTLFTDLFE 316
>P35509:KC1G3_BOVIN Casein kinase I isoform gamma-3 - Bos taurus (Bovine)| Length = 276 Score = 160 bits (406), Expect = 2e-38 Identities = 83/226 (36%), Positives = 136/226 (60%) Frame = +3 Query: 564 PQYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVY 743 P ++V +K+G G FG++ +G+ + VA+K E S+ E++ Y Sbjct: 27 PNFRVGKKIGCGNFGELRLGKNLYTNEY--------VAIKLEPMKSRAPQLH--LEYRFY 76 Query: 744 SSLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISIL 923 L GIP V+Y G G Y +V+++LGPSL D+++ +T + V IA++ IS + Sbjct: 77 KQLGSGDGIPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFSLKTVLMIAIQLISRM 136 Query: 924 EKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIF 1103 E +H+K ++ DVKPENFL+G+PG+ ++ + +ID GLA ++ + + +H+ Y + + Sbjct: 137 EYVHSKNLIYRDVKPENFLIGRPGNKTQQVIHIIDFGLAKEYIDPETKKHIPYREHKSL- 195 Query: 1104 RGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGD 1241 GT RY S++ HLG+ SRRDDLE+L + ++ LRG LPWQG + D Sbjct: 196 TGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKAD 241
>Q3UVR3:TTBK2_MOUSE Tau-tubulin kinase 2 - Mus musculus (Mouse)| Length = 1243 Score = 118 bits (296), Expect = 1e-25 Identities = 96/304 (31%), Positives = 151/304 (49%), Gaps = 3/304 (0%) Frame = +3 Query: 507 GGGEDDASPVPEKVQVGH--SPQYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVAL 680 GGGE P+ + VG ++KV RK+G GGFG++Y + VAL Sbjct: 3 GGGEQ-----PDILSVGILVKERWKVLRKIGGGGFGEIYDALDML--------TRENVAL 49 Query: 681 KFEHRNSKGCNYGPPYEWQVYSSLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNS 860 K E +++ E V L G + GR + +VM + G +L D+ S Sbjct: 50 KVE--SAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRS 107 Query: 861 LGQ-TMTPSMVACIAVEAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGL 1037 + T T S + + + +E +H+ GF+H D+KP NF +G+ S +K F++D GL Sbjct: 108 QSRGTFTISTTLRLGKQILESIESIHSVGFLHRDIKPSNFAMGRFPSTC-RKCFMLDFGL 166 Query: 1038 ASKWKETSSGQHVDYDQRPDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRL 1217 A ++ T+S V + FRGT+RYAS++AH R R DDL SL Y L+ + G+L Sbjct: 167 ARQF--TNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVVGQL 224 Query: 1218 PWQGYQGDNKSFLVCKKKMSISPDLMCCYCAPPFKLFLETVTNMKFDEEPNYPKLISLFD 1397 PW+ + + V K LM + P F FL+ ++++ + +P+Y L S+FD Sbjct: 225 PWRKIKDKEQ---VGSIKERYDHRLMLKHLPPEFSTFLDHISSLDYFTKPDYQLLTSVFD 281 Query: 1398 ELIE 1409 I+ Sbjct: 282 NSIK 285
>Q6IQ55:TTBK2_HUMAN Tau-tubulin kinase 2 - Homo sapiens (Human)| Length = 1244 Score = 115 bits (288), Expect = 1e-24 Identities = 88/282 (31%), Positives = 143/282 (50%), Gaps = 1/282 (0%) Frame = +3 Query: 567 QYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYS 746 ++KV RK+G GGFG++Y + VALK E +++ E V Sbjct: 20 RWKVLRKIGGGGFGEIYDALDML--------TRENVALKVE--SAQQPKQVLKMEVAVLK 69 Query: 747 SLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQ-TMTPSMVACIAVEAISIL 923 L G + GR + +VM + G +L D+ S + T T S + + + + Sbjct: 70 KLQGKDHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESI 129 Query: 924 EKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIF 1103 E +H+ GF+H D+KP NF +G+ S +K +++D GLA ++ T+S V + F Sbjct: 130 ESIHSVGFLHRDIKPSNFAMGRFPSTC-RKCYMLDFGLARQF--TNSCGDVRPPRAVAGF 186 Query: 1104 RGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNKSFLVCKKKMSIS 1283 RGT+RYAS++AH R R DDL SL Y L+ + G+LPW+ + + V K Sbjct: 187 RGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVVGQLPWRKIKDKEQ---VGSIKERYD 243 Query: 1284 PDLMCCYCAPPFKLFLETVTNMKFDEEPNYPKLISLFDELIE 1409 LM + P F +FL+ ++++ + +P+Y L S+FD I+ Sbjct: 244 HRLMLKHLPPEFSIFLDHISSLDYFTKPDYQLLTSVFDNSIK 285
>Q6PCN3:TTBK1_MOUSE Tau-tubulin kinase 1 - Mus musculus (Mouse)| Length = 1308 Score = 113 bits (282), Expect = 5e-24 Identities = 88/303 (29%), Positives = 148/303 (48%), Gaps = 5/303 (1%) Frame = +3 Query: 504 IGGGEDDASPVPEKVQVGHSPQYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALK 683 + GG + A +P V ++KV +K+G GGFG++Y + VALK Sbjct: 14 MSGGGEQADILPANYVV--KDRWKVLKKIGGGGFGEIYEAMDLL--------TRENVALK 63 Query: 684 FEHRNSKGCNYGPPYEWQVYSSLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSL 863 E +++ E V L G + GR + +VM + G +L D+ S Sbjct: 64 VE--SAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNEKFNYVVMQLQGRNLADLRRSQ 121 Query: 864 GQ-TMTPSMVACIAVEAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLA 1040 + T T S + + + +E +H+ GF+H D+KP NF +G+ S +K +++D GLA Sbjct: 122 PRGTFTLSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPST-YRKCYMLDFGLA 180 Query: 1041 SKWKETSSGQHVDYDQRPDI----FRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLR 1208 ++ T+ D RP FRGT+RYASV+AH R R DDL SL Y L+ Sbjct: 181 RQYTNTTG------DVRPPRNVAGFRGTVRYASVNAHKNREMGRHDDLWSLFYMLVEFAV 234 Query: 1209 GRLPWQGYQGDNKSFLVCKKKMSISPDLMCCYCAPPFKLFLETVTNMKFDEEPNYPKLIS 1388 G+LPW+ + + ++ K ++ + F LFL+ + ++ + +P+Y ++S Sbjct: 235 GQLPWRKIKDKEQVGMI---KEKYEHRMLLKHMPSEFHLFLDHIASLDYFTKPDYQLIMS 291 Query: 1389 LFD 1397 +F+ Sbjct: 292 VFE 294
>Q5TCY1:TTBK1_HUMAN Tau-tubulin kinase 1 - Homo sapiens (Human)| Length = 1321 Score = 113 bits (282), Expect = 5e-24 Identities = 88/303 (29%), Positives = 148/303 (48%), Gaps = 5/303 (1%) Frame = +3 Query: 504 IGGGEDDASPVPEKVQVGHSPQYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALK 683 + GG + A +P V ++KV +K+G GGFG++Y + VALK Sbjct: 14 MSGGGEQADILPANYVV--KDRWKVLKKIGGGGFGEIYEAMDLL--------TRENVALK 63 Query: 684 FEHRNSKGCNYGPPYEWQVYSSLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSL 863 E +++ E V L G + GR + +VM + G +L D+ S Sbjct: 64 VE--SAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNEKFNYVVMQLQGRNLADLRRSQ 121 Query: 864 GQ-TMTPSMVACIAVEAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLA 1040 + T T S + + + +E +H+ GF+H D+KP NF +G+ S +K +++D GLA Sbjct: 122 PRGTFTLSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPST-YRKCYMLDFGLA 180 Query: 1041 SKWKETSSGQHVDYDQRPDI----FRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLR 1208 ++ T+ D RP FRGT+RYASV+AH R R DDL SL Y L+ Sbjct: 181 RQYTNTTG------DVRPPRNVAGFRGTVRYASVNAHKNREMGRHDDLWSLFYMLVEFAV 234 Query: 1209 GRLPWQGYQGDNKSFLVCKKKMSISPDLMCCYCAPPFKLFLETVTNMKFDEEPNYPKLIS 1388 G+LPW+ + + ++ K ++ + F LFL+ + ++ + +P+Y ++S Sbjct: 235 GQLPWRKIKDKEQVGMI---KEKYEHRMLLKHMPSEFHLFLDHIASLDYFTKPDYQLIMS 291 Query: 1389 LFD 1397 +F+ Sbjct: 292 VFE 294
>Q9J523:V212_FOWPV Probable serine/threonine-protein kinase FPV212 - Fowlpox virus (FPV)| Length = 303 Score = 107 bits (267), Expect = 3e-22 Identities = 87/309 (28%), Positives = 154/309 (49%), Gaps = 21/309 (6%) Frame = +3 Query: 531 PVPEKVQVGHSPQYK--VERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSK 704 P+PE + + K + ++LG GGFG VY +VS ++ + K E + S Sbjct: 10 PLPEGTLLEDITKNKWILGKQLGSGGFGLVY---QVSCKSKEI-----DCVAKIELKESG 61 Query: 705 GC------------NYGPPYEWQVYSSLNGCYGIPWVHYKG----RQGDYYVLVMDILGP 836 G N W ++ GIP H G + +Y ++ LG Sbjct: 62 GLFCEINFYNRVMKNKTSLDTWMKEQKID-YIGIPSFHGFGITIYKNVEYRFAIIQRLGR 120 Query: 837 SLWDVWNSLGQTMTPSMVACIAVEAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKL 1016 L ++ + + +++ +A++ + IL+ +H+K F HGD+K N L G+ D+ K+ Sbjct: 121 DLENILSEK-EKFNITVIKKLAIKILDILKFIHSKEFSHGDIKAGNILFGK----DDDKV 175 Query: 1017 FLIDLGLASKWKETSSGQHVDYDQRP-DIFRGTIRYASVHAHLGRTGSRRDDLESLAYTL 1193 +L+D GLA+K+ +S+G+H +Y P + GT+ + S+ AH G T SRR DLESL + + Sbjct: 176 YLVDYGLATKY--SSNGKHKEYTINPKNRHNGTMAFTSIDAHKGVTVSRRGDLESLGFCM 233 Query: 1194 IFLLRGRLPWQGYQGDNKSFLVCKKKM--SISPDLMCCYCAPPFKLFLETVTNMKFDEEP 1367 + G+LPW+ Y+ + ++ K+ +IS + A +++ VT ++++E P Sbjct: 234 LKWYSGKLPWEKYEKEPENVQGMKEAFVNNISKKTIPFKNAGIIYNYIKVVTKLEYEEAP 293 Query: 1368 NYPKLISLF 1394 NY L +F Sbjct: 294 NYESLKQMF 302
>P34516:YMX8_CAEEL Putative serine/threonine-protein kinase K06H7.1 - Caenorhabditis| elegans Length = 346 Score = 105 bits (261), Expect = 1e-21 Identities = 87/310 (28%), Positives = 140/310 (45%), Gaps = 9/310 (2%) Frame = +3 Query: 567 QYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYS 746 +YKV +KLG+GG G V+ E T ALK E ++ N E Q+ S Sbjct: 19 RYKVVQKLGEGGCGSVFK-------VEDTSEKGQHYALKVEFKSQDAGNI-LKMEVQILS 70 Query: 747 SLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISILE 926 L + G++ Y +VM +LG SL + G + S I + + ++ Sbjct: 71 QLISKKHVAKCVASGKKERYSYMVMTLLGESLDSLLKKHGPFLNVSTQVRIGICILFGIK 130 Query: 927 KLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKW-KETSSGQHVDYDQRPDIF 1103 ++H G++H D+KP N +G GS DE+ ++D GLA ++ + G + + F Sbjct: 131 QVHDIGYLHRDLKPANVAMGCKGSADERYFLVLDFGLARQYIADEDDGLKMRRPREKTYF 190 Query: 1104 RGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNKSFLVCKKKMSIS 1283 RGT RY SV H R DDL +L Y ++ +R RL W + D+K + + K I Sbjct: 191 RGTARYCSVAMHDRYEQGRVDDLWALVY-ILAEMRCRLAW--HDVDDK-VEIGEMKRKIH 246 Query: 1284 PDLMCCYCAPPFKLFLETVTNMKFDEEPNYPKLISLFDELI--------EPQHLRPIRID 1439 +++ F++TV + F P+Y KL L ++++ +P H P + Sbjct: 247 DEVLFAKSPVQMLSFVKTVRSTLFYHRPDYEKLFKLLEDVMKCANYKWSDPYHWEPEKKK 306 Query: 1440 GALKAGQKRG 1469 G K G Sbjct: 307 NPASQGNKFG 316
>O57252:VPK1_VACCA Serine/threonine-protein kinase 1 - Vaccinia virus (strain Ankara)| (VACV) Length = 300 Score = 101 bits (252), Expect = 1e-20 Identities = 84/290 (28%), Positives = 133/290 (45%), Gaps = 19/290 (6%) Frame = +3 Query: 567 QYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNS---KGCNYGPPYEWQ 737 Q+ V +GKGGFG +Y T + Y V ++ + S + Y + Sbjct: 15 QWVVGPLIGKGGFGSIYT----------TNDNNYVVKIEPKANGSLFTEQAFYTRVLKPS 64 Query: 738 VYSSLNGCYGIPWVH---------YKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMV 890 V + I V YK +Y LV++ LG L V + + V Sbjct: 65 VIEEWKKSHNIKHVGLITCKAFGLYKSINVEYRFLVINRLGADLDAVIRANNNRLPKRSV 124 Query: 891 ACIAVEAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQ 1070 I +E ++ ++ +H +G+ HGD+K N +L Q D+ KL+L+D GL SK+ S+G+ Sbjct: 125 MLIGIEILNTIQFMHEQGYSHGDIKASNIVLDQ---IDKNKLYLVDYGLVSKF--MSNGE 179 Query: 1071 HVDYDQRPD-IFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNK 1247 HV + + P+ + GT+ + + +H G SRR DLE+L Y +I L G LPW Sbjct: 180 HVPFIRNPNKMDNGTLEFTPIDSHKGYVVSRRGDLETLGYCMIRWLGGILPWTKISETKN 239 Query: 1248 SFLVCKKKM----SISPDLMCCYCAPPFKL--FLETVTNMKFDEEPNYPK 1379 LV K + + LM P +L ++ V ++ + EEPNY K Sbjct: 240 CALVSATKQKYVNNTATLLMTSLQYAPRELLQYITMVNSLTYFEEPNYDK 289
>P16913:VPK1_VACCV Serine/threonine-protein kinase 1 - Vaccinia virus (strain Western| Reserve / WR) (VACV) Length = 300 Score = 100 bits (248), Expect = 4e-20 Identities = 83/288 (28%), Positives = 132/288 (45%), Gaps = 19/288 (6%) Frame = +3 Query: 567 QYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNS---KGCNYGPPYEWQ 737 Q+ V +GKGGFG +Y T + Y V ++ + S + Y + Sbjct: 15 QWVVGPLIGKGGFGSIYT----------TNDNNYVVKIEPKANGSLFTEQAFYTRVLKPS 64 Query: 738 VYSSLNGCYGIPWVH---------YKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMV 890 V + I V YK +Y LV++ LG L V + + V Sbjct: 65 VIEEWKKSHNIKHVGLITCKAFGLYKSINVEYRFLVINRLGADLDAVIRANNNRLPKRSV 124 Query: 891 ACIAVEAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQ 1070 I +E ++ ++ +H +G+ HGD+K N +L Q D+ KL+L+D GL SK+ S+G+ Sbjct: 125 MLIGIEILNTIQFMHEQGYSHGDIKASNIVLDQ---IDKNKLYLVDYGLVSKF--MSNGE 179 Query: 1071 HVDYDQRPD-IFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNK 1247 HV + + P+ + GT+ + + +H G SRR DLE+L Y +I L G LPW Sbjct: 180 HVPFIRNPNKMDNGTLEFTPIDSHKGYVVSRRGDLETLGYCMIRWLGGILPWTKISETKN 239 Query: 1248 SFLVCKKKM----SISPDLMCCYCAPPFKL--FLETVTNMKFDEEPNY 1373 LV K + + LM P +L ++ V ++ + EEPNY Sbjct: 240 CALVSATKQKYVNNTATLLMTSLQYAPRELLQYITMVNSLTYFEEPNY 287
>P20505:VPK1_VACCC Serine/threonine-protein kinase 1 - Vaccinia virus (strain| Copenhagen) (VACV) Length = 300 Score = 99.8 bits (247), Expect = 5e-20 Identities = 83/288 (28%), Positives = 132/288 (45%), Gaps = 19/288 (6%) Frame = +3 Query: 567 QYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNS---KGCNYGPPYEWQ 737 Q+ V +GKGGFG +Y T + Y V ++ + S + Y + Sbjct: 15 QWVVGPLIGKGGFGSIYT----------TNDNNYVVKIEPKANGSLFTEQAFYTRVLKPS 64 Query: 738 VYSSLNGCYGIPWVH---------YKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMV 890 V + I V YK +Y LV++ LG L V + + V Sbjct: 65 VIEEWKKSHNIKHVGLITCKAFGLYKSINVEYRFLVINRLGVDLDAVIRANNNRLPKRSV 124 Query: 891 ACIAVEAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQ 1070 I +E ++ ++ +H +G+ HGD+K N +L Q D+ KL+L+D GL SK+ S+G+ Sbjct: 125 MLIGIEILNTIQFMHEQGYSHGDIKASNIVLDQ---IDKNKLYLVDYGLVSKF--MSNGE 179 Query: 1071 HVDYDQRPD-IFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNK 1247 HV + + P+ + GT+ + + +H G SRR DLE+L Y +I L G LPW Sbjct: 180 HVPFIRNPNKMDNGTLEFTPIDSHKGYVVSRRGDLETLGYCMIRWLGGILPWTKISETKN 239 Query: 1248 SFLVCKKKM----SISPDLMCCYCAPPFKL--FLETVTNMKFDEEPNY 1373 LV K + + LM P +L ++ V ++ + EEPNY Sbjct: 240 CALVSATKQKYVNNTATLLMTSLQYAPRELLQYITMVNSLTYFEEPNY 287
>Q86Y07:VRK2_HUMAN Serine/threonine-protein kinase VRK2 - Homo sapiens (Human)| Length = 508 Score = 99.4 bits (246), Expect = 7e-20 Identities = 90/300 (30%), Positives = 135/300 (45%), Gaps = 28/300 (9%) Frame = +3 Query: 567 QYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVA-------------LKFEHRNSKG 707 Q+ + +K+G GGFG +Y+ + T + DA V LKF R +K Sbjct: 28 QWVLGKKIGSGGFGLIYL----AFPTNKPEKDARHVVKVEYQENGPLFSELKFYQRVAKK 83 Query: 708 CNYGPPYEWQV--YSSLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTP 881 E + Y + YG +KGR Y +VM+ LG L + G T Sbjct: 84 DCIKKWIERKQLDYLGIPLFYGSGLTEFKGRS--YRFMVMERLGIDLQKISGQNG-TFKK 140 Query: 882 SMVACIAVEAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETS 1061 S V + + + +LE +H +VHGD+K N LLG +PD+ ++L D GL+ ++ Sbjct: 141 STVLQLGIRMLDVLEYIHENEYVHGDIKAANLLLGYK-NPDQ--VYLADYGLSYRY--CP 195 Query: 1062 SGQHVDYDQRPDI-FRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQG 1238 +G H Y + P GTI + S+ AH G SRR D+E L Y ++ L G+LPW+ Q Sbjct: 196 NGNHKQYQENPRKGHNGTIEFTSLDAHKGVALSRRSDVEILGYCMLRWLCGKLPWE--QN 253 Query: 1239 DNKSFLVCKKKMSISPDL------------MCCYCAPPFKLFLETVTNMKFDEEPNYPKL 1382 V K ++ +L CC A FL ++ +DE+PNY L Sbjct: 254 LKDPVAVQTAKTNLLDELPQSVLKWAPSGSSCCEIAQ----FLVCAHSLAYDEKPNYQAL 309
>P33800:VPK1_VARV Serine/threonine-protein kinase 1 - Variola virus| Length = 300 Score = 98.6 bits (244), Expect = 1e-19 Identities = 79/285 (27%), Positives = 133/285 (46%), Gaps = 14/285 (4%) Frame = +3 Query: 567 QYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYS 746 Q+ V +GKGGFG +Y + + P A + ++ EW+ Sbjct: 15 QWVVGPLIGKGGFGSIYTTND-NNYVVKIEPKANGSLFTEQAFYTRVLKPSVIEEWKKSH 73 Query: 747 SLNG-------CYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAV 905 ++ +G+ YK +Y LV++ LG L V + + V + + Sbjct: 74 HISHVGVITCKAFGL----YKSINTEYRFLVINRLGVDLDAVIRANNNRLPKRSVMLVGI 129 Query: 906 EAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYD 1085 E ++ ++ +H +G+ HG++K N +L Q D+ KL+L+D GL SK+ S+G+HV + Sbjct: 130 EILNTIQFMHEQGYSHGNIKASNIVLDQM---DKNKLYLVDYGLVSKFM--SNGEHVPFI 184 Query: 1086 QRPD-IFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNKSFLVC 1262 + P+ + GT+ + + +H G SRR DLE+L Y +I L G LPW LV Sbjct: 185 RNPNKMDNGTLEFTPIDSHKGYVVSRRGDLETLGYCMIRWLGGILPWTKIAETKNCALVS 244 Query: 1263 KKKM----SISPDLMCCYCAPPFKL--FLETVTNMKFDEEPNYPK 1379 K + + LM P +L ++ V ++ + EEPNY K Sbjct: 245 ATKQKYVNNTTTLLMTSLQYAPRELLQYITMVNSLTYFEEPNYDK 289
>Q99986:VRK1_HUMAN Serine/threonine-protein kinase VRK1 - Homo sapiens (Human)| Length = 396 Score = 98.2 bits (243), Expect = 2e-19 Identities = 88/299 (29%), Positives = 136/299 (45%), Gaps = 27/299 (9%) Frame = +3 Query: 567 QYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVA-------------LKFEHRNSKG 707 ++KV +G+GGFG +Y+ S +E G DA V LKF R +K Sbjct: 36 EWKVGLPIGQGGFGCIYLADMNS--SESVGSDAPCVVKVEPSDNGPLFTELKFYQRAAK- 92 Query: 708 CNYGPPYEWQVYSSLNGC--YGIP--W---VHYKGRQGDYYVLVMDILGPSLWDVWNSLG 866 P + Q + G+P W +H K + Y ++MD G L ++ + Sbjct: 93 -----PEQIQKWIRTRKLKYLGVPKYWGSGLHDKNGKS-YRFMIMDRFGSDLQKIYEANA 146 Query: 867 QTMTPSMVACIAVEAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASK 1046 + + V +++ + ILE +H +VHGD+K N LL +PD+ ++L+D GLA + Sbjct: 147 KRFSRKTVLQLSLRILDILEYIHEHEYVHGDIKASNLLLNYK-NPDQ--VYLVDYGLAYR 203 Query: 1047 WKETSSGQHVDYDQRPD-IFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPW 1223 + G H +Y + P GTI + S+ AH G SRR DLE L Y +I L G LPW Sbjct: 204 Y--CPEGVHKEYKEDPKRCHDGTIEFTSIDAHNGVAPSRRGDLEILGYCMIQWLTGHLPW 261 Query: 1224 QGYQGDNKSFLVCKKKMSISPDLMCCYCAP------PFKLFLETVTNMKFDEEPNYPKL 1382 + D K K + + + C P ++ETV + + E+P Y L Sbjct: 262 EDNLKDPKYVRDSKIRYRENIASLMDKCFPEKNKPGEIAKYMETVKLLDYTEKPLYENL 320
>O19175:KC1A_PIG Casein kinase I isoform alpha - Sus scrofa (Pig)| Length = 125 Score = 97.8 bits (242), Expect = 2e-19 Identities = 55/127 (43%), Positives = 78/127 (61%) Frame = +3 Query: 669 EVALKFEHRNSKGCNYGPPYEWQVYSSLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWD 848 EVA+K E + ++ YE ++Y L G GIP + + G++ DY VLVMD+LGPSL D Sbjct: 3 EVAVKLESQKARHPQL--LYESKLYKILQGGVGIPHIRWYGQEKDYNVLVMDLLGPSLED 60 Query: 849 VWNSLGQTMTPSMVACIAVEAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLID 1028 ++N + T V +A + IS +E +H K F+H D+KP+NFL+G KLFLID Sbjct: 61 LFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFIHRDIKPDNFLMGI--GRHCNKLFLID 118 Query: 1029 LGLASKW 1049 GLA K+ Sbjct: 119 FGLAKKY 125
>Q7ZUS1:VRK1_DANRE Serine/threonine-protein kinase VRK1 - Danio rerio (Zebrafish)| (Brachydanio rerio) Length = 425 Score = 94.7 bits (234), Expect = 2e-18 Identities = 106/416 (25%), Positives = 176/416 (42%), Gaps = 50/416 (12%) Frame = +3 Query: 477 KMDGVSPEKIGGGEDDASPVP--EKVQVGHSPQYKVERKLGKGGFGQVYVGRRVSGG-TE 647 K DGV + A P E + ++K+ +G+GGFG +Y+ S G Sbjct: 5 KADGVKKARAPAKRKLAEEFPSGEVLTDNAKKKWKLGSAVGQGGFGLLYLANEDSSGPVT 64 Query: 648 RTGPDAYEVA----------LKFEHRNSKGCNYGP--PYEWQVYSSLNGCYGIPWVHYKG 791 P +V LKF R +K G + Y + +G + G Sbjct: 65 ADAPYVIKVEPSDNGPLFSELKFYMRAAKPDLIGAWMKSKKMEYLGVPKYWGSGFHEKNG 124 Query: 792 RQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISILEKLHAKGFVHGDVKPE 971 ++ Y +VMD G L ++ G+ + +V + + + ILE +H +VH D+K Sbjct: 125 KR--YRFMVMDRFGTDLQKLFEGNGKKFSRKLVLQLGLRLLDILEYIHDHEYVHADIKAS 182 Query: 972 NFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPD-IFRGTIRYASVHAHLGR 1148 N LL + ++FL+D GLA ++ G +Y + P GTI + S+ AH G Sbjct: 183 NLLLSYT---NPNQVFLVDYGLAYRY--APEGVPKEYKEDPKRCHDGTIEFTSIDAHKGV 237 Query: 1149 TGSRRDDLESLAYTLIFLLRGRLPWQGYQGD----NKSFLVCKKKMSISPDLMCCYCAP- 1313 + SRR DLE + Y +I L RLPW+ D S L C+ +I L C+ + Sbjct: 238 SPSRRADLEIMGYCMIQWLCSRLPWEDKLQDPLYVRDSKLRCRD--NIDEFLKSCFASGN 295 Query: 1314 -PFKL--FLETVTNMKFDEEPNYPKLISLFDELIE---------------------PQHL 1421 P ++ F++ V + + + P+Y KL + + ++ P Sbjct: 296 IPAEMGKFMQEVKVLGYTDRPDYDKLRGILQQGLKSIGSTDDKKLDFGVATNSTSLPSVK 355 Query: 1422 RPIRIDGALKAGQKRGRVSHEEDEQPRKKVRLGSPANQWI-----SVYNAKRPMKQ 1574 P R K +++G+ + E D P KK R +P + + + AKRP+K+ Sbjct: 356 TPKR-----KKAEEKGQSADETDSTPAKKRR--APQKKEVNGAKKTASPAKRPVKK 404
>Q32PI1:VRK1_BOVIN Serine/threonine-protein kinase VRK1 - Bos taurus (Bovine)| Length = 396 Score = 94.4 bits (233), Expect = 2e-18 Identities = 90/322 (27%), Positives = 143/322 (44%), Gaps = 23/322 (7%) Frame = +3 Query: 567 QYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVA-------------LKFEHRNSKG 707 ++K+ +G+GGFG +Y+ S ++ G DA V LKF R +K Sbjct: 36 EWKLGSPIGQGGFGCIYLADMNS--SKSVGNDAPCVVKVEPSDNGPLFTELKFYQRAAK- 92 Query: 708 CNYGPPYEWQVYSSLNGC--YGIP--W---VHYKGRQGDYYVLVMDILGPSLWDVWNSLG 866 P + Q + + G+P W +H K + Y +++D G L ++ + Sbjct: 93 -----PEQIQKWIRTHKLKYLGVPKYWGSGLHDKNGKS-YRFMIIDRFGSDLQKIYEANA 146 Query: 867 QTMTPSMVACIAVEAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASK 1046 + + V +++ + ILE +H +VHGD+K N LL +PD+ ++L+D GLA + Sbjct: 147 KRFSRKTVLQLSLRILDILEYIHEHEYVHGDIKASNLLLSYK-NPDQ--VYLVDYGLAYR 203 Query: 1047 WKETSSGQHVDYDQRPD-IFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPW 1223 + G H +Y + P GT+ + S+ AH G SRR DLE L Y +I L G LPW Sbjct: 204 Y--CPEGTHKEYKEDPKRCHDGTVEFTSIDAHNGVAPSRRGDLEILGYCMIQWLSGHLPW 261 Query: 1224 QGYQGDNKSFLVCKKKMSISPDLMCCYCAPPFKLFLETVTNMKFDEEPNYPKLISLFDEL 1403 + D K + + + C P K DE Y + + L D + Sbjct: 262 EDNLKDPNYVRDSKIRYRENIASLMDKCFP---------EKNKPDEIAKYMETVKLLDYV 312 Query: 1404 IEP--QHLRPIRIDGALKAGQK 1463 +P Q LR I + G G K Sbjct: 313 EKPLYQKLRDILLQGLKAIGSK 334
>Q80X41:VRK1_MOUSE Serine/threonine-protein kinase VRK1 - Mus musculus (Mouse)| Length = 440 Score = 94.0 bits (232), Expect = 3e-18 Identities = 93/347 (26%), Positives = 152/347 (43%), Gaps = 28/347 (8%) Frame = +3 Query: 567 QYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVA-------------LKFEHRNSKG 707 ++K+ +G+GGFG +Y+ + ++ G DA V LKF R +K Sbjct: 36 EWKLGLPIGQGGFGCIYLAD--TNSSKPVGSDAPCVVKVEPSDNGPLFTELKFYQRAAK- 92 Query: 708 CNYGPPYEWQVYSSLNGC--YGIP--W---VHYKGRQGDYYVLVMDILGPSLWDVWNSLG 866 P + Q + + G+P W +H K + Y ++MD G L ++ + Sbjct: 93 -----PEQIQKWIRTHKLKYLGVPKYWGSGLHDKNGKS-YRFMIMDRFGSDLQKIYEANA 146 Query: 867 QTMTPSMVACIAVEAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASK 1046 + + V +++ + ILE +H +VHGD+K N LL +PD+ ++L+D GLA + Sbjct: 147 KRFSRKTVLQLSLRILDILEYIHEHEYVHGDIKASNLLLSHK-NPDQ--VYLVDYGLAYR 203 Query: 1047 WKETSSGQHVDYDQRPD-IFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPW 1223 + G H +Y + P GT+ + S+ AH G SRR DLE L Y +I L G LPW Sbjct: 204 Y--CPDGVHKEYKEDPKRCHDGTLEFTSIDAHKGVAPSRRGDLEILGYCMIQWLSGCLPW 261 Query: 1224 QGYQGDNKSFLVCKKKMSISPDLMCCYCAP------PFKLFLETVTNMKFDEEPNYPKLI 1385 + D K + + + C P ++E+V +++ E+P Y Sbjct: 262 EDNLKDPNYVRDSKIRYRDNVAALMEKCFPEKNKPGEIAKYMESVKLLEYTEKPLY---- 317 Query: 1386 SLFDELIEPQHLRPIRIDGALKAGQK-RGRVSHEEDEQPRKKVRLGS 1523 Q+LR I + G G K G++ E K R S Sbjct: 318 ---------QNLRDILLQGLKAIGSKDDGKLDFSAVENGSVKTRPAS 355
>Q8BN21:VRK2_MOUSE Serine/threonine-protein kinase VRK2 - Mus musculus (Mouse)| Length = 503 Score = 90.9 bits (224), Expect = 3e-17 Identities = 103/414 (24%), Positives = 175/414 (42%), Gaps = 22/414 (5%) Frame = +3 Query: 567 QYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVA-------------LKFEHRNSKG 707 ++ + + +G GGFG +Y+ + T + DA V LKF R +K Sbjct: 28 RWALGKMIGSGGFGLIYL----AFPTNKPNKDARHVIKLEYQENGPLFSELKFYQRAAKR 83 Query: 708 -CNYGPPYEWQV-YSSLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTP 881 C + ++ Y + YG +KGR Y +VM+ LG L + + G Sbjct: 84 ECIQKWIQQRKLDYLGIPVFYGFGLTDFKGRS--YRFMVMERLGIDLQKLLDQNGGFKKL 141 Query: 882 SMVACIAVEAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETS 1061 +++ + + + +LE +H +VHGD+K N LL +PD +++L D GL+ ++ Sbjct: 142 TVLQ-LGIRMLDVLEYIHENEYVHGDIKAANLLLDFT-NPD--RVYLADYGLSYRY--CP 195 Query: 1062 SGQHVDYDQRPDI-FRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQG 1238 +G H Y + P GTI + S+ AH G SRR D+E L Y ++ L G+LPW+ Sbjct: 196 NGNHKQYQEDPRKGHNGTIEFTSLDAHKGVAPSRRSDVEILGYCMLHWLFGKLPWEAKLD 255 Query: 1239 DNKSFLVCKKKMSISPDLMCCYCAP------PFKLFLETVTNMKFDEEPNYPKLISLFDE 1400 D + K + AP +L V N+ +D++P+Y KL + Sbjct: 256 DPVAVQTAKTNLLDELPESVLKWAPSGSSCSELVKYLMYVHNLAYDDKPDYQKL----KK 311 Query: 1401 LIEPQHLRPIRIDGALKAGQKRGRVSHEEDEQPRKKVRLGSPANQWISVYNAKRPMKQRY 1580 ++ P + ++ + K R ++ K R PAN+ + AK P K Sbjct: 312 ILNPDGVPLGPLEFSTKVQSVHVRTPAQQKVDSPKATR--KPANE----FPAKFPKKVH- 364 Query: 1581 HYNVAEARLHQHIEKGNEDGLFISSVASSANLWALIMDAGTGFTSQVYELSPIF 1742 E R Q E+ + + S ++ T +++E S IF Sbjct: 365 ----RETRARQREEQEDSQPTMLQSRPAAPE---------NSRTRKIHEYSDIF 405
>P24362:KRB2_VACCV Probable serine/threonine-protein kinase B12 - Vaccinia virus (strain| Western Reserve / WR) (VACV) Length = 283 Score = 90.1 bits (222), Expect = 4e-17 Identities = 74/259 (28%), Positives = 119/259 (45%), Gaps = 16/259 (6%) Frame = +3 Query: 666 YEVALKFEHRNSKGCNYGPPYEWQVYSSLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLW 845 Y +K +H++ K P ++ ++ + ++ +G Y+ + D+ G Sbjct: 40 YNYVMKIDHKSHK------PLLSEIRFYISVLDPLTIDNWTRERGIKYLAIPDLYGIGET 93 Query: 846 D-----VWNSLGQTMTPSMVACI---AVEAISILEKLHAKGFVHGDVKPENFLLGQPGSP 1001 D V +LG+ P + V I+ LE +H++GF HG ++P N L+ Sbjct: 94 DDYMFFVIKNLGRVFAPKDTESVFEACVTMINTLEFIHSQGFTHGKIEPRNILIRN---- 149 Query: 1002 DEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFRGTIRYASVHAHLGRTGSRRDDLESL 1181 K+L LID +K + S H+DY++ I G I Y V HLG T SRR DLE L Sbjct: 150 --KRLSLIDYSRTNKLYK-SGNSHIDYNEDM-ITSGNINYMCVDNHLGATVSRRGDLEML 205 Query: 1182 AYTLIFLLRGRLPWQGYQGDNKSFLVCKKKMSISPDLMCCY--CAP----PFKL--FLET 1337 Y +I G+LPW+ + S V K+K + + C P P +L ++E Sbjct: 206 GYCMIEWFGGKLPWK----NESSIKVIKQKKEYKKFIATFFEDCFPEGNEPLELVRYIEL 261 Query: 1338 VTNMKFDEEPNYPKLISLF 1394 V + + + PNY +L LF Sbjct: 262 VYTLDYSQTPNYDRLRKLF 280
>P21098:KRB2_VACCC Probable serine/threonine-protein kinase B12 - Vaccinia virus (strain| Copenhagen) (VACV) Length = 283 Score = 90.1 bits (222), Expect = 4e-17 Identities = 74/259 (28%), Positives = 119/259 (45%), Gaps = 16/259 (6%) Frame = +3 Query: 666 YEVALKFEHRNSKGCNYGPPYEWQVYSSLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLW 845 Y +K +H++ K P ++ ++ + ++ +G Y+ + D+ G Sbjct: 40 YNYVMKIDHKSHK------PLLSEIRFYISVLDPLTIDNWTRERGIKYLAIPDLYGIGET 93 Query: 846 D-----VWNSLGQTMTPSMVACI---AVEAISILEKLHAKGFVHGDVKPENFLLGQPGSP 1001 D V +LG+ P + V I+ LE +H++GF HG ++P N L+ Sbjct: 94 DDYMFFVIKNLGRVFAPKDTESVFEACVTMINTLEFIHSRGFTHGKIEPRNILIRN---- 149 Query: 1002 DEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFRGTIRYASVHAHLGRTGSRRDDLESL 1181 K+L LID +K + S H+DY++ I G I Y V HLG T SRR DLE L Sbjct: 150 --KRLSLIDYSRTNKLYK-SGNSHIDYNEDM-ITSGNINYMCVDNHLGATVSRRGDLEML 205 Query: 1182 AYTLIFLLRGRLPWQGYQGDNKSFLVCKKKMSISPDLMCCY--CAP----PFKL--FLET 1337 Y +I G+LPW+ + S V K+K + + C P P +L ++E Sbjct: 206 GYCMIEWFGGKLPWK----NESSIKVIKQKKEYKKFIATFFEDCFPEGNEPLELVRYIEL 261 Query: 1338 VTNMKFDEEPNYPKLISLF 1394 V + + + PNY +L LF Sbjct: 262 VYTLDYSQTPNYDRLRRLF 280
>Q7KRY6:NHK1_DROME Nucleosomal histone kinase 1 - Drosophila melanogaster (Fruit fly)| Length = 599 Score = 89.7 bits (221), Expect = 6e-17 Identities = 89/330 (26%), Positives = 141/330 (42%), Gaps = 38/330 (11%) Frame = +3 Query: 534 VPEKVQVGH------SPQYKVERKLGKGGFGQVYVGRRVSGGT-------ERTGPDAYEV 674 +PEKV+ G Q+++ +G GGFG++Y +V E G V Sbjct: 29 MPEKVKEGTVFTDLAKGQWRIGPSIGVGGFGEIYAACKVGEKNYDAVVKCEPHGNGPLFV 88 Query: 675 ALKFEHRNSKGCNYGPPYEWQVYSSLNGCYGIPWVHYKGR---QGDYY-VLVMDILGPSL 842 + F RN+K + + SL G+P++ G G+ + +VM G L Sbjct: 89 EMHFYLRNAKLEDIKQFMQKHGLKSL----GMPYILANGSVEVNGEKHRFIVMPRYGSDL 144 Query: 843 WDVWNSLGQTMTPSMVACIAVEAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFL 1022 G+ + V +A++ + + + +H+ G+VH D+K N LLG + +L Sbjct: 145 TKFLEQNGKRLPEGTVYRLAIQMLDVYQYMHSNGYVHADLKAANILLGLE-KGGAAQAYL 203 Query: 1023 IDLGLASKWKETSSGQHVDYDQRPD---IFRGTIRYASVHAHLGRTGSRRDDLESLAYTL 1193 +D GLAS + V D +PD + GTI Y S AHLG +RR DLE L Y L Sbjct: 204 VDFGLASHF--------VTGDFKPDPKKMHNGTIEYTSRDAHLG-VPTRRADLEILGYNL 254 Query: 1194 IFLLRGRLPWQGYQGDNKSFLVCKKKMSISPDLMCCYCA------------------PPF 1319 I L LPW V +K +++ P + A PP Sbjct: 255 IEWLGAELPW-----------VTQKLLAVPPKVQKAKEAFMDNIGESLKTLFPKGVPPPI 303 Query: 1320 KLFLETVTNMKFDEEPNYPKLISLFDELIE 1409 F++ V+ + ++EP+Y K S F ++ Sbjct: 304 GDFMKYVSKLTHNQEPDYDKCRSWFSSALK 333
>O57259:KRB2_VACCA Probable serine/threonine-protein kinase B12 - Vaccinia virus (strain| Ankara) (VACV) Length = 283 Score = 89.0 bits (219), Expect = 1e-16 Identities = 73/259 (28%), Positives = 119/259 (45%), Gaps = 16/259 (6%) Frame = +3 Query: 666 YEVALKFEHRNSKGCNYGPPYEWQVYSSLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLW 845 Y +K +H++ K P ++ ++ + ++ +G Y+ + D+ G Sbjct: 40 YNYVMKIDHKSHK------PLLSEIRFYISVLDPLTIDNWTRERGIKYLAIPDLYGIGET 93 Query: 846 D-----VWNSLGQTMTPSMVACI---AVEAISILEKLHAKGFVHGDVKPENFLLGQPGSP 1001 D V +LG+ P + V I+ LE +H++GF HG ++P N L+ Sbjct: 94 DDYMFFVIKNLGRVFAPKDTESVFEACVTMINTLEFIHSRGFTHGKIEPRNILIRN---- 149 Query: 1002 DEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFRGTIRYASVHAHLGRTGSRRDDLESL 1181 K+L LID +K + S H+DY++ I G I Y V HLG T S+R DLE L Sbjct: 150 --KRLSLIDYSRTNKLYK-SGNSHIDYNEDM-ITSGNINYMCVDNHLGATVSKRGDLEML 205 Query: 1182 AYTLIFLLRGRLPWQGYQGDNKSFLVCKKKMSISPDLMCCY--CAP----PFKL--FLET 1337 Y +I G+LPW+ + S V K+K + + C P P +L ++E Sbjct: 206 GYCMIEWFGGKLPWK----NESSIKVIKQKKEYKKFIATFFEDCFPEGNEPLELVRYIEL 261 Query: 1338 VTNMKFDEEPNYPKLISLF 1394 V + + + PNY +L LF Sbjct: 262 VYTLDYSQTPNYDRLRRLF 280
>Q9J509:V226_FOWPV Probable serine/threonine-protein kinase FPV226 - Fowlpox virus (FPV)| Length = 292 Score = 85.5 bits (210), Expect = 1e-15 Identities = 83/308 (26%), Positives = 143/308 (46%), Gaps = 26/308 (8%) Frame = +3 Query: 558 HSPQYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRN-----SKGCNYGP 722 + Q+K+++ +G GGFG VY + + + + +K E N S+ Y Sbjct: 10 YGKQWKIDKLIGCGGFGCVY--------STQCASNTRQAVIKVESLNNTTMVSEVLVYNN 61 Query: 723 PYE------WQVYSSLNGCYGIPWVHYKG---RQGDYYVLVMDILGPSLWDVWNSLGQTM 875 Y+ W+ Y +++ GIP + G R YY ++ L + + L + Sbjct: 62 IYDKNRIALWKNYKNIDHL-GIPMYYGCGSFKRNTMYYRFIL--LERLVENTKELLKRVK 118 Query: 876 TPS-MVACIAVEAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWK 1052 P ++ I + + LE +H G HGD+KPEN ++ + +LID G+ S + Sbjct: 119 KPKPLIKNIMKDMLYTLEYIHEHGISHGDIKPENIMVD-----GRYRSYLIDYGIVSYF- 172 Query: 1053 ETSSGQHVDY-DQRPDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQG 1229 +G+HV Y + + RGT+ YAS+ AH G +RR DLESL Y ++ LPW+ Sbjct: 173 -IVNGKHVKYYKESKNWHRGTLYYASLDAHNGTCVTRRGDLESLGYCMLKWAGIPLPWKV 231 Query: 1230 YQGDNKSFL----------VCKKKMSISPDLMCCYCAPPFKLFLETVTNMKFDEEPNYPK 1379 + G+N + + V K K++I Y +++ VT + ++E+P+Y Sbjct: 232 F-GNNGNMVHVAKCDFIKRVHKNKVNIKSANKGIYD------YIKCVTKLSYEEKPDYDL 284 Query: 1380 LISLFDEL 1403 L L + L Sbjct: 285 LRQLVNSL 292
>P42169:YKL2_CAEEL Putative casein kinase I C03C10.2 - Caenorhabditis elegans| Length = 363 Score = 84.0 bits (206), Expect = 3e-15 Identities = 65/223 (29%), Positives = 108/223 (48%), Gaps = 3/223 (1%) Frame = +3 Query: 567 QYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHR-NSKGCNYGPPYEWQVY 743 ++ +E +G GG+GQ+++ V ER A+K E + ++ E QV Sbjct: 71 RWSIEGVIGNGGYGQIFMVMDVKKNDER--------AMKIEPKLRAEVITKRMIMEQQVL 122 Query: 744 SSLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVW--NSLGQTMTPSMVACIAVEAIS 917 + G IP ++ G + ++M +L ++ D + LG+ ++ V IA + ++ Sbjct: 123 MKMQGKTHIPTMYASGFNDQFNFIIMQLLSMNVGDFRKRSPLGR-LSKETVGRIAYQTLN 181 Query: 918 ILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPD 1097 L+ +H G+VH DVKP N G + L+L+D GL ++K T SG + + Sbjct: 182 ALKDIHDMGYVHRDVKPANICFGVHAQ-NRHILYLLDFGLVRRFK-TESGVCIPWRINAG 239 Query: 1098 IFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQ 1226 F+GT RY SV H + DD S+ YT L+ G LPW+ Sbjct: 240 -FKGTERYVSVRVHEKLEQTPWDDAFSVLYTAYELVVGELPWR 281
>Q8IV63:VRK3_HUMAN Serine/threonine-protein kinase VRK3 - Homo sapiens (Human)| Length = 474 Score = 73.9 bits (180), Expect = 3e-12 Identities = 77/310 (24%), Positives = 134/310 (43%), Gaps = 23/310 (7%) Frame = +3 Query: 567 QYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYE----- 731 Q+K++ + G +Y S T +GP + +LK + ++ + N ++ Sbjct: 165 QWKLKSFQTRDNQGILYEAAPTSTLTCDSGPQKQKFSLKLDAKDGRLFNEQNFFQRAAKP 224 Query: 732 -----WQ-VYSS----LNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWN-SLGQTMT 878 W+ +YS+ + C G VH Q Y LV+ LG SL + S ++ Sbjct: 225 LQVNKWKKLYSTPLLAIPTCMGFG-VH----QDKYRFLVLPSLGRSLQSALDVSPKHVLS 279 Query: 879 PSMVACIAVEAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKET 1058 V +A + LE LH +VHG+V EN + D+ ++ L G A ++ Sbjct: 280 ERSVLQVACRLLDALEFLHENEYVHGNVTAENIFVDPE---DQSQVTLAGYGFAFRY--C 334 Query: 1059 SSGQHVDY-DQRPDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQ 1235 SG+HV Y + G + + S+ H G SRR DL+SL Y ++ L G LPW Sbjct: 335 PSGKHVAYVEGSRSPHEGDLEFISMDLHKGCGPSRRSDLQSLGYCMLKWLYGFLPWTNCL 394 Query: 1236 GDNKSFLVCKKKMSISPDLMCCYC------APPFKLFLETVTNMKFDEEPNYPKLISLFD 1397 + + + K+K P C + + +L+ V + ++E+P Y L + + Sbjct: 395 PNTEDIMKQKQKFVDKPGPFVGPCGHWIRPSETLQKYLKVVMALTYEEKPPYAMLRNNLE 454 Query: 1398 ELIEPQHLRP 1427 L++ + P Sbjct: 455 ALLQDLRVSP 464
>Q09503:YQI1_CAEEL Uncharacterized protein C45G9.1 - Caenorhabditis elegans| Length = 290 Score = 73.2 bits (178), Expect = 5e-12 Identities = 58/229 (25%), Positives = 118/229 (51%), Gaps = 9/229 (3%) Frame = +3 Query: 768 IPWVHYKGRQGDYYVLVMDILGPSLWDVWNS---LGQTMTPSMVACIAVEAISILEKLHA 938 IP ++ G++ ++ +VM +LG +L D+ ++ + + + + + ++ + L+ +H Sbjct: 18 IPNLNLYGKKMNFSYMVMTLLGRNLQDLESTNFVVNKGFSRGTWSRVGIQWVYALKYVHY 77 Query: 939 KGFVHGDVKPENFLLGQPGSPDEKKLF-LIDLGLASKWKETSSGQH---VDYDQRPDIFR 1106 GF+H +V +N LG + K+ ++D GL + + ++ V + FR Sbjct: 78 NGFIHRNVNTQNLFLGNEKDSERAKIIHILDFGLGRPFARYHARENKWIVRIARHSAEFR 137 Query: 1107 GTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGR-LPWQGYQGDNKSFLVCKKKMSIS 1283 G+ RYAS + HL + R DD+ SL Y +I L G+ LPW Q D + V + K++++ Sbjct: 138 GSFRYASPNVHLRKEQGRVDDVWSLPYVIIELNGGKALPW---QTDYRRGRVEQMKLNLT 194 Query: 1284 P-DLMCCYCAPPFKLFLETVTNMKFDEEPNYPKLISLFDELIEPQHLRP 1427 P D+M A KL + + ++ + + P+ + F +++E + + P Sbjct: 195 PKDVMSDMPACMDKL-MPHLASLNYYQRPDDHMIFKCFWQVMENEKITP 242
>P54736:PKN2_MYXXA Serine/threonine-protein kinase pkn2 - Myxococcus xanthus| Length = 830 Score = 72.0 bits (175), Expect = 1e-11 Identities = 65/225 (28%), Positives = 103/225 (45%), Gaps = 4/225 (1%) Frame = +3 Query: 567 QYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRN---SKGCNYGPPYEWQ 737 +++V R LG GG G+VY+G +VS G +VA+K H + G E + Sbjct: 12 RFRVLRPLGSGGMGEVYLGEQVSLGR--------KVAIKVLHHDLHAQAGMAERFKREAR 63 Query: 738 VYSSLNGCYGIPWVHYKGRQGDYYVLVMDIL-GPSLWDVWNSLGQTMTPSMVACIAVEAI 914 + S++ + V + G GD+ LVM+ + G SL+DV M P + + Sbjct: 64 LLSAVEHPAVVRIVDF-GESGDHACLVMEFVEGESLYDVLTP--GPMPPGRALPLLQQLA 120 Query: 915 SILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRP 1094 L +H KG +H D+KPEN + + ++ + L+D G+A + E + V + Sbjct: 121 EGLAAIHDKGIIHRDLKPENVFISKSARGEQAR--LLDFGIA-RLVEPDAASSV---SQI 174 Query: 1095 DIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQG 1229 + GT Y S +G R DL S +L GRLP+ G Sbjct: 175 GVVLGTPEYLSPEQAVGAKVDTRSDLYSFGVLTYRVLSGRLPFDG 219
>Q8K3G5:VRK3_MOUSE Serine/threonine-protein kinase VRK3 - Mus musculus (Mouse)| Length = 453 Score = 70.5 bits (171), Expect = 4e-11 Identities = 55/219 (25%), Positives = 97/219 (44%), Gaps = 8/219 (3%) Frame = +3 Query: 795 QGDYYVLVMDILGPSLWDVWNSLGQ-TMTPSMVACIAVEAISILEKLHAKGFVHGDVKPE 971 Q Y LV LG SL + + ++ V +A + LE LH +VHG++ E Sbjct: 230 QDKYRFLVFPSLGRSLQSALDDNPKHVVSERCVLQVACRLLDALEYLHENEYVHGNLTAE 289 Query: 972 NFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRP-DIFRGTIRYASVHAHLGR 1148 N + D ++ L+ G ++ G+HV Y + G + + S+ H G Sbjct: 290 NVFVNPE---DLSQVTLVGYGFTYRY--CPGGKHVAYKEGSRSPHDGDLEFISMDLHKGC 344 Query: 1149 TGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNKSFLVCKKKMSISPDLMCCYC------A 1310 SRR DL++L Y ++ L G LPW + + K+K SP+ + C + Sbjct: 345 GPSRRSDLQTLGYCMLKWLYGSLPWTNCLPNTEKITRQKQKYLDSPERLVGLCGRWNKAS 404 Query: 1311 PPFKLFLETVTNMKFDEEPNYPKLISLFDELIEPQHLRP 1427 + +L+ V + ++E+P Y L + + L++ + P Sbjct: 405 ETLREYLKVVMALNYEEKPPYATLRNSLEALLQDMRVSP 443
>P81123:KC1D_RABIT Casein kinase I isoform delta - Oryctolagus cuniculus (Rabbit)| Length = 81 Score = 68.6 bits (166), Expect = 1e-10 Identities = 34/78 (43%), Positives = 51/78 (65%) Frame = +3 Query: 966 PENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFRGTIRYASVHAHLG 1145 P+NFL+G +++ID GLA K+++ + QH+ Y + ++ GT RYAS++ HLG Sbjct: 4 PDNFLMGL--GKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNL-TGTARYASINTHLG 60 Query: 1146 RTGSRRDDLESLAYTLIF 1199 SRRDDLESL Y L++ Sbjct: 61 IEQSRRDDLESLGYVLMY 78
>Q7TPS0:KS6A6_MOUSE Ribosomal protein S6 kinase alpha-6 - Mus musculus (Mouse)| Length = 764 Score = 67.4 bits (163), Expect = 3e-10 Identities = 69/259 (26%), Positives = 116/259 (44%), Gaps = 9/259 (3%) Frame = +3 Query: 531 PVPEKVQVGHSP----QYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEV-ALKFEHR 695 P+ + V+ G+ Q+ + + LG+G FG+V++ R+ +TGPDA ++ A+K + Sbjct: 76 PITQHVKEGYEKADPAQFDLLKVLGQGSFGKVFLVRK------KTGPDAGQLYAMKVLRK 129 Query: 696 NSKGCN--YGPPYEWQVYSSLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQ 869 S E + +N + I +HY + L++D L DV+ L + Sbjct: 130 ASLKVRDRVRTKMERDILVEVNHPF-IVKLHYAFQTEGKLYLILDFLRGG--DVFTRLSK 186 Query: 870 TM--TPSMVACIAVEAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLAS 1043 + T V E L+ LH G V+ D+KPEN LL + G + L D GL Sbjct: 187 EVLFTEEDVKFYLAELALALDHLHRLGIVYRDLKPENILLDEIGH-----IKLTDFGL-- 239 Query: 1044 KWKETSSGQHVDYDQRPDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPW 1223 S + VD +++ F GT+ Y + R S+ D S + +L G LP+ Sbjct: 240 ------SKESVDQEKKAYSFCGTVEYMAPEVVNRRAHSQSADWWSYGVLMFEMLTGTLPF 293 Query: 1224 QGYQGDNKSFLVCKKKMSI 1280 QG + ++ K K+ + Sbjct: 294 QGKDRNETMNMILKAKLGM 312
>Q9UK32:KS6A6_HUMAN Ribosomal protein S6 kinase alpha-6 - Homo sapiens (Human)| Length = 745 Score = 66.2 bits (160), Expect = 7e-10 Identities = 69/259 (26%), Positives = 116/259 (44%), Gaps = 9/259 (3%) Frame = +3 Query: 531 PVPEKVQVGHSP----QYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEV-ALKFEHR 695 P+ V+ G+ Q+++ + LG+G FG+V++ R+ +TGPDA ++ A+K + Sbjct: 56 PITHHVKEGYEKADPAQFELLKVLGQGSFGKVFLVRK------KTGPDAGQLYAMKVLKK 109 Query: 696 NSKGCN--YGPPYEWQVYSSLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQ 869 S E + +N + I +HY + L++D L DV+ L + Sbjct: 110 ASLKVRDRVRTKMERDILVEVNHPF-IVKLHYAFQTEGKLYLILDFLRGG--DVFTRLSK 166 Query: 870 TM--TPSMVACIAVEAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLAS 1043 + T V E L+ LH G V+ D+KPEN LL + G + L D GL Sbjct: 167 EVLFTEEDVKFYLAELALALDHLHQLGIVYRDLKPENILLDEIGH-----IKLTDFGL-- 219 Query: 1044 KWKETSSGQHVDYDQRPDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPW 1223 S + VD +++ F GT+ Y + R S+ D S + +L G LP+ Sbjct: 220 ------SKESVDQEKKAYSFCGTVEYMAPEVVNRRGHSQSADWWSYGVLMFEMLTGTLPF 273 Query: 1224 QGYQGDNKSFLVCKKKMSI 1280 QG + ++ K K+ + Sbjct: 274 QGKDRNETMNMILKAKLGM 292
>Q6PFQ0:KS6A6_DANRE Ribosomal protein S6 kinase alpha-6 - Danio rerio (Zebrafish)| (Brachydanio rerio) Length = 740 Score = 65.9 bits (159), Expect = 9e-10 Identities = 68/254 (26%), Positives = 113/254 (44%), Gaps = 5/254 (1%) Frame = +3 Query: 534 VPEKVQVGHSPQYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEV-ALKFEHRNSKGC 710 V E + Q+++ + LG+G FG+V++ R++ G PDA ++ A+K + S Sbjct: 55 VKEGCEKADPSQFELLKVLGQGSFGKVFLVRKLMG------PDAGQLYAMKVLKKASLKV 108 Query: 711 N--YGPPYEWQVYSSLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTM--T 878 E + +N + I +HY + L++D L DV+ L + + T Sbjct: 109 RDRVRTKMERDILVEVNHPF-IVKLHYAFQTEGKLYLILDFLRGG--DVFTRLSKEVMFT 165 Query: 879 PSMVACIAVEAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKET 1058 V E L+ LH G V+ D+KPEN LL + G + L D GL Sbjct: 166 EEDVKFYLAELALALDHLHNLGIVYRDLKPENILLDEAGH-----IKLTDFGL------- 213 Query: 1059 SSGQHVDYDQRPDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQG 1238 S + VD D++ F GT+ Y + R ++ D SL + +L G LP+QG Sbjct: 214 -SKESVDQDKKAYSFCGTVEYMAPEVVNRRGHTQSADWWSLGVLMFEMLTGTLPFQGKDR 272 Query: 1239 DNKSFLVCKKKMSI 1280 + ++ K K+ + Sbjct: 273 NETMNMILKAKLGM 286
>P51812:KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 - Homo sapiens (Human)| Length = 740 Score = 65.9 bits (159), Expect = 9e-10 Identities = 64/273 (23%), Positives = 118/273 (43%), Gaps = 17/273 (6%) Frame = +3 Query: 513 GEDDASPVPEKVQV-----------GHSP----QYKVERKLGKGGFGQVYVGRRVSGGTE 647 GE++ +P E+V + GH Q+++ + LG+G FG+V++ +++SG Sbjct: 34 GEEEINPQTEEVSIKEIAITHHVKEGHEKADPSQFELLKVLGQGSFGKVFLVKKISGSDA 93 Query: 648 RTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYSSLNGCYGIPWVHYKGRQGDYYVLVMDI 827 R Y + + + E + +N + I +HY + L++D Sbjct: 94 R---QLYAMKVLKKATLKVRDRVRTKMERDILVEVNHPF-IVKLHYAFQTEGKLYLILDF 149 Query: 828 LGPSLWDVWNSLGQTM--TPSMVACIAVEAISILEKLHAKGFVHGDVKPENFLLGQPGSP 1001 L D++ L + + T V E L+ LH+ G ++ D+KPEN LL + G Sbjct: 150 LRGG--DLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEEG-- 205 Query: 1002 DEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFRGTIRYASVHAHLGRTGSRRDDLESL 1181 + L D GL S + +D++++ F GT+ Y + R ++ D S Sbjct: 206 ---HIKLTDFGL--------SKESIDHEKKAYSFCGTVEYMAPEVVNRRGHTQSADWWSF 254 Query: 1182 AYTLIFLLRGRLPWQGYQGDNKSFLVCKKKMSI 1280 + +L G LP+QG ++ K K+ + Sbjct: 255 GVLMFEMLTGTLPFQGKDRKETMTMILKAKLGM 287 Score = 33.1 bits (74), Expect = 6.3 Identities = 17/43 (39%), Positives = 27/43 (62%), Gaps = 1/43 (2%) Frame = +3 Query: 921 LEKLHAKGFVHGDVKPENFL-LGQPGSPDEKKLFLIDLGLASK 1046 +E LHA+G VH D+KP N L + + G+P+ + + D G A + Sbjct: 527 VEYLHAQGVVHRDLKPSNILYVDESGNPE--SIRICDFGFAKQ 567
>P18654:KS6A3_MOUSE Ribosomal protein S6 kinase alpha-3 - Mus musculus (Mouse)| Length = 740 Score = 65.1 bits (157), Expect = 1e-09 Identities = 63/282 (22%), Positives = 124/282 (43%), Gaps = 6/282 (2%) Frame = +3 Query: 453 EEFADKVVKMDGVSPEKIGGGEDDASPVPEKVQVGHSP----QYKVERKLGKGGFGQVYV 620 ++ D+ + + ++P+ G + + + V+ GH Q+++ + LG+G FG+V++ Sbjct: 26 QQIMDEPMGEEEINPQTEEGSIKEIA-ITHHVKEGHEKADPSQFELLKVLGQGSFGKVFL 84 Query: 621 GRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYSSLNGCYGIPWVHYKGRQG 800 +++SG R Y + + + E + +N + I +HY + Sbjct: 85 VKKISGSDAR---QLYAMKVLKKATLKVRDRVRTKMERDILVEVNHPF-IVKLHYAFQTE 140 Query: 801 DYYVLVMDILGPSLWDVWNSLGQTM--TPSMVACIAVEAISILEKLHAKGFVHGDVKPEN 974 L++D L D++ L + + T V E L+ LH+ G ++ D+KPEN Sbjct: 141 GKLYLILDFLRGG--DLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGIIYRDLKPEN 198 Query: 975 FLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFRGTIRYASVHAHLGRTG 1154 LL + G + L D GL S + +D++++ F GT+ Y + R Sbjct: 199 ILLDEEG-----HIKLTDFGL--------SKESIDHEKKAYSFCGTVEYMAPEVVNRRGH 245 Query: 1155 SRRDDLESLAYTLIFLLRGRLPWQGYQGDNKSFLVCKKKMSI 1280 ++ D S + +L G LP+QG ++ K K+ + Sbjct: 246 TQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGM 287 Score = 33.1 bits (74), Expect = 6.3 Identities = 17/43 (39%), Positives = 27/43 (62%), Gaps = 1/43 (2%) Frame = +3 Query: 921 LEKLHAKGFVHGDVKPENFL-LGQPGSPDEKKLFLIDLGLASK 1046 +E LHA+G VH D+KP N L + + G+P+ + + D G A + Sbjct: 527 VEYLHAQGVVHRDLKPSNILYVDESGNPE--SIRICDFGFAKQ 567
>Q15349:KS6A2_HUMAN Ribosomal protein S6 kinase alpha-2 - Homo sapiens (Human)| Length = 733 Score = 64.7 bits (156), Expect = 2e-09 Identities = 67/260 (25%), Positives = 113/260 (43%), Gaps = 6/260 (2%) Frame = +3 Query: 519 DDASPVPEKVQVGHSPQYKVERKLGKGGFGQVYVGRRVSG---GTERTGPDAYEVALKFE 689 D + V E + Q+++ + LG+G +G+V++ R+V G G + LK Sbjct: 42 DISHHVKEGFEKADPSQFELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVR 101 Query: 690 HR-NSKGCNYGPPYEWQVYSSLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLG 866 R SK E + + +N + I +HY + L++D L D++ L Sbjct: 102 DRVRSK-------MERDILAEVNHPF-IVKLHYAFQTEGKLYLILDFLRGG--DLFTRLS 151 Query: 867 QTM--TPSMVACIAVEAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLA 1040 + + T V E L+ LH+ G ++ D+KPEN LL + G + + D GL Sbjct: 152 KEVMFTEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEEGH-----IKITDFGL- 205 Query: 1041 SKWKETSSGQHVDYDQRPDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLP 1220 S + +D+D+R F GTI Y + R ++ D S + +L G LP Sbjct: 206 -------SKEAIDHDKRAYSFCGTIEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGSLP 258 Query: 1221 WQGYQGDNKSFLVCKKKMSI 1280 +QG L+ K K+ + Sbjct: 259 FQGKDRKETMALILKAKLGM 278
>Q9WUT3:KS6A2_MOUSE Ribosomal protein S6 kinase alpha-2 - Mus musculus (Mouse)| Length = 733 Score = 64.3 bits (155), Expect = 3e-09 Identities = 67/260 (25%), Positives = 113/260 (43%), Gaps = 6/260 (2%) Frame = +3 Query: 519 DDASPVPEKVQVGHSPQYKVERKLGKGGFGQVYVGRRVSG---GTERTGPDAYEVALKFE 689 D ++ V E + Q+++ + LG+G +G+V++ R+V+G G + LK Sbjct: 42 DISNHVKEGFEKADPSQFELLKVLGQGSYGKVFLVRKVTGSDAGQLYAMKVLKKATLKVR 101 Query: 690 HR-NSKGCNYGPPYEWQVYSSLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLG 866 R SK E + + +N + I +HY + L++D L D++ L Sbjct: 102 DRVRSK-------MERDILAEVNHPF-IVKLHYAFQTEGKLYLILDFLRGG--DLFTRLS 151 Query: 867 QTM--TPSMVACIAVEAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLA 1040 + + T V E L+ LH G ++ D+KPEN LL + G + + D GL Sbjct: 152 KEVMFTEEDVKFYLAELALALDHLHGLGIIYRDLKPENILLDEEGH-----IKITDFGL- 205 Query: 1041 SKWKETSSGQHVDYDQRPDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLP 1220 S + D+D+R F GTI Y + R ++ D S + +L G LP Sbjct: 206 -------SKEATDHDKRAYSFCGTIEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGSLP 258 Query: 1221 WQGYQGDNKSFLVCKKKMSI 1280 +QG L+ K K+ + Sbjct: 259 FQGKDRKETMALILKAKLGM 278 Score = 33.1 bits (74), Expect = 6.3 Identities = 27/86 (31%), Positives = 44/86 (51%), Gaps = 3/86 (3%) Frame = +3 Query: 798 GDYYVLVMDIL-GPSLWDVWNSLGQTMTPSMVACIAVEAIS-ILEKLHAKGFVHGDVKPE 971 G Y LVM+++ G L D L Q A + I+ ++ LH++G VH D+KP Sbjct: 479 GKYVYLVMELMRGGELLD--RILRQRCFSEREASDVLYTIARTMDYLHSQGVVHRDLKPS 536 Query: 972 NFL-LGQPGSPDEKKLFLIDLGLASK 1046 N L + + G+P+ + + D G A + Sbjct: 537 NILYMDESGNPE--SIRICDFGFAKQ 560
>P34635:YOO3_CAEEL Putative serine/threonine-protein kinase ZK507.3 - Caenorhabditis| elegans Length = 374 Score = 63.2 bits (152), Expect = 6e-09 Identities = 72/288 (25%), Positives = 119/288 (41%), Gaps = 9/288 (3%) Frame = +3 Query: 537 PEKVQVGHSPQY--KVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGC 710 P ++ P Y KV +LGKGG+G V + + E D E A+K E + + Sbjct: 12 PNEIIKRTKPDYNWKVIVELGKGGYGTV--NKVIKVNEEGFAIDDKEYAMKTEQKFASKH 69 Query: 711 NYGPPYEWQVYSSLNGCYGIPWVHYK-----GRQGDYYVLVMDILGPSLWDVWNSLGQT- 872 + E V +S + C H+ G+ + +VM I+GPSL ++ + Sbjct: 70 SSRLKIERNVMASYSKCDAQCKEHFPELIDFGQSPVWKWIVMTIVGPSLEELKMKYKPSD 129 Query: 873 MTPSMVACIAVEAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWK 1052 + PS + ++ + + H GF+H D+KP N+ +G GS E ++++D GLA K Sbjct: 130 IPPSTILQCGLQTMKAIHDFHQIGFLHRDIKPANYCIGY-GSKSE-TIYVLDFGLARK-- 185 Query: 1053 ETSSGQHVDYDQRPDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRL-PWQG 1229 +R Y S +H RRDD ES + I L+ L W+G Sbjct: 186 ----------------YRLPEWYCSRASHRCEELGRRDDYESWFFMFIDLVDTTLIDWKG 229 Query: 1230 YQGDNKSFLVCKKKMSISPDLMCCYCAPPFKLFLETVTNMKFDEEPNY 1373 + KK + L P FK+ + + +D + + Sbjct: 230 LTRPD----AYAKKQELFTKLKTYEKEPMFKVISIYLDTLVYDSDVKF 273
>P34633:YOO1_CAEEL Putative serine/threonine-protein kinase ZK507.1 - Caenorhabditis| elegans Length = 331 Score = 63.2 bits (152), Expect = 6e-09 Identities = 55/189 (29%), Positives = 89/189 (47%), Gaps = 2/189 (1%) Frame = +3 Query: 813 LVMDILGPSLWDVWNSLGQT-MTPSMVACIAVEAISILEKLHAKGFVHGDVKPENFLLGQ 989 +VM I+GPSL ++ + + PS + ++ + + H GF+H D+KP N+ +G Sbjct: 67 IVMTIVGPSLEELKMKYKPSDIPPSTILQCGLQTMKAIHDFHQIGFLHRDIKPANYCIGY 126 Query: 990 PGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFRGTIRYASVHAHLGRTGSRRDD 1169 GS E ++++D GLA K++ +GQ V + GT RY S +H RRDD Sbjct: 127 -GSKSE-TIYVLDFGLARKYR-LPNGQ-VRPPRPKTKMIGTPRYCSRASHRCEELGRRDD 182 Query: 1170 LESLAYTLIFLLRGRL-PWQGYQGDNKSFLVCKKKMSISPDLMCCYCAPPFKLFLETVTN 1346 ES + I L+ L W+G + KK + L P FK+ + N Sbjct: 183 YESWFFMFIDLVDTTLIDWKGLTRPD----AYAKKQELFTKLKTYEKHPMFKVISIYLDN 238 Query: 1347 MKFDEEPNY 1373 + +D E + Sbjct: 239 LVYDSEVKF 247
>P65732:PKNJ_MYCTU Probable serine/threonine-protein kinase pknJ - Mycobacterium| tuberculosis Length = 589 Score = 63.2 bits (152), Expect = 6e-09 Identities = 67/230 (29%), Positives = 101/230 (43%), Gaps = 7/230 (3%) Frame = +3 Query: 570 YKVERKLGKGGFGQVYVGRRVS-GGTERTGPDAYEVA--LKFEHRNSKGCNYGPPYEWQV 740 Y++ER LG GG G VY+ R +E A E++ L F R + E V Sbjct: 14 YRIERMLGAGGMGTVYLARNPDLPRSEALKVLAAELSRDLDFRARFVR--------EADV 65 Query: 741 YSSLNGCYGIPWVHYKGR-QGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAIS 917 + L+ I VH +G+ +G ++ + + G + D + TMT + + E Sbjct: 66 AAGLDHP-NIVAVHQRGQFEGRLWIAMQFVDGGNAEDALRAA--TMTTARAVYVIGEVAK 122 Query: 918 ILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKE---TSSGQHVDYDQ 1088 L+ H +G +H D+KP NFLL + DE+ L L D G+A + TS+G + Sbjct: 123 ALDYAHQQGVIHRDIKPANFLLSRAAGGDERVL-LSDFGIARALGDTGLTSTGSVL---- 177 Query: 1089 RPDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQG 1238 T+ YA+ G+ R DL SL L LL G P+ G Sbjct: 178 ------ATLAYAAPEVLAGQGFDGRADLYSLGCALFRLLTGEAPFAAGAG 221
>P65733:PKNJ_MYCBO Probable serine/threonine-protein kinase pknJ - Mycobacterium bovis| Length = 589 Score = 63.2 bits (152), Expect = 6e-09 Identities = 67/230 (29%), Positives = 101/230 (43%), Gaps = 7/230 (3%) Frame = +3 Query: 570 YKVERKLGKGGFGQVYVGRRVS-GGTERTGPDAYEVA--LKFEHRNSKGCNYGPPYEWQV 740 Y++ER LG GG G VY+ R +E A E++ L F R + E V Sbjct: 14 YRIERMLGAGGMGTVYLARNPDLPRSEALKVLAAELSRDLDFRARFVR--------EADV 65 Query: 741 YSSLNGCYGIPWVHYKGR-QGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAIS 917 + L+ I VH +G+ +G ++ + + G + D + TMT + + E Sbjct: 66 AAGLDHP-NIVAVHQRGQFEGRLWIAMQFVDGGNAEDALRAA--TMTTARAVYVIGEVAK 122 Query: 918 ILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKE---TSSGQHVDYDQ 1088 L+ H +G +H D+KP NFLL + DE+ L L D G+A + TS+G + Sbjct: 123 ALDYAHQQGVIHRDIKPANFLLSRAAGGDERVL-LSDFGIARALGDTGLTSTGSVL---- 177 Query: 1089 RPDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQG 1238 T+ YA+ G+ R DL SL L LL G P+ G Sbjct: 178 ------ATLAYAAPEVLAGQGFDGRADLYSLGCALFRLLTGEAPFAAGAG 221
>Q21734:KS6A1_CAEEL Putative ribosomal protein S6 kinase alpha-1 - Caenorhabditis elegans| Length = 784 Score = 62.8 bits (151), Expect = 7e-09 Identities = 61/240 (25%), Positives = 106/240 (44%), Gaps = 2/240 (0%) Frame = +3 Query: 567 QYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYS 746 Q+++ + LG+G FG+V++ R+V G R Y + + + E + + Sbjct: 103 QFELLKVLGQGSFGKVFLVRKVRG---RDSGHVYAMKVLKKATLKVRDRQRTKLERNILA 159 Query: 747 SLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTM--TPSMVACIAVEAISI 920 ++ + I +HY + L++D L D++ L + + T V E Sbjct: 160 HISHPF-IVKLHYAFQTEGKLYLILDFLRGG--DLFTRLSKEVMFTEDDVKFYLAELTLA 216 Query: 921 LEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDI 1100 LE LH+ G V+ D+KPEN LL G + + D GL S + +D +++ Sbjct: 217 LEHLHSLGIVYRDLKPENILLDADGH-----IKVTDFGL--------SKEAIDSEKKTYS 263 Query: 1101 FRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNKSFLVCKKKMSI 1280 F GT+ Y + R S D SL + +L G LP+QG ++ + K K+S+ Sbjct: 264 FCGTVEYMAPEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILKAKLSM 323
>P33973:PKN1_MYXXA Serine/threonine-protein kinase pkn1 - Myxococcus xanthus| Length = 693 Score = 61.2 bits (147), Expect = 2e-08 Identities = 61/224 (27%), Positives = 95/224 (42%), Gaps = 6/224 (2%) Frame = +3 Query: 570 YKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYS- 746 +++ R+LG+GG G VY+G VS G+ VA+K H + P + ++ Sbjct: 59 FRLVRRLGRGGMGAVYLGEHVSIGSR--------VAVKVLHAH---LTMYPELVQRFHAE 107 Query: 747 ----SLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAI 914 +L G I + L+M+ L + W +G + V + + Sbjct: 108 ARAVNLIGHENIVSIFDMDATPPRPYLIMEFLDGAPLSAW--VGTPLAAGAVVSVLSQVC 165 Query: 915 SILEKLHAKGFVHGDVKPEN-FLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQR 1091 L+ HA+G VH D+KP+N FL+ + G+ K ++D G+A H Sbjct: 166 DALQAAHARGIVHRDLKPDNIFLVRRNGNAPFVK--VLDFGIAKLADAHMPQTHA----- 218 Query: 1092 PDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPW 1223 I GT Y + LGR R DL +L LL GRLP+ Sbjct: 219 -GIIVGTPEYMAPEQSLGRGVDGRADLYALGVIAYQLLTGRLPF 261
>Q8R9T6:PKN1_THETN Probable serine/threonine-protein kinase Sps1 - Thermoanaerobacter| tengcongensis Length = 625 Score = 59.3 bits (142), Expect = 8e-08 Identities = 58/229 (25%), Positives = 100/229 (43%), Gaps = 8/229 (3%) Frame = +3 Query: 567 QYKVERKLGKGGFGQVY------VGRRVSGGTERTGPDAYE-VALKFEHRNSKGCNYGPP 725 +Y++ K+G+GG +VY + R V+ R A E KF+ + + P Sbjct: 9 RYEILEKIGEGGMAKVYKAKCHLLNRIVAIKILRPEFAADENFVKKFKRESQAAASLSHP 68 Query: 726 YEWQVYSSLNGCYGIPWVHYKGRQGDYYVLVMD-ILGPSLWDVWNSLGQTMTPSMVACIA 902 ++ G Y + G++GD Y +VM+ + G +L ++ G + IA Sbjct: 69 -------NIVGIYDV------GQEGDIYYIVMEYVKGRTLKELIRENGGPLEVKRAVEIA 115 Query: 903 VEAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDY 1082 + L+ H +H D+KP+N L+ DE + + D G+A ++G + Y Sbjct: 116 SQVCRALDHAHKNKIIHRDIKPQNILV-----TDEDVVKVTDFGIA----RAANGATITY 166 Query: 1083 DQRPDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQG 1229 D+ GT Y S G R D+ SL L +L G++P++G Sbjct: 167 --TGDVI-GTAYYFSPEQAKGSIVDERTDIYSLGIVLFEMLTGKVPFEG 212
>P18652:KS6AA_CHICK Ribosomal protein S6 kinase 2 alpha - Gallus gallus (Chicken)| Length = 752 Score = 58.9 bits (141), Expect = 1e-07 Identities = 61/254 (24%), Positives = 112/254 (44%), Gaps = 5/254 (1%) Frame = +3 Query: 534 VPEKVQVGHSPQYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEV-ALKFEHRNSKGC 710 V E + Q+++ + LG+G FG+V++ R++ T PD+ + A+K + + Sbjct: 68 VKEGSEKADPSQFELLKVLGQGSFGKVFLVRKI------TPPDSNHLYAMKVLKKATLKV 121 Query: 711 N--YGPPYEWQVYSSLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTM--T 878 E + + +N + + +HY + L++D L D++ L + + T Sbjct: 122 RDRVRTKIERDILADVNHPFVVK-LHYAFQTEGKLYLILDFLRGG--DLFTRLSKEVMFT 178 Query: 879 PSMVACIAVEAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKET 1058 V E L+ LH+ G ++ D+KPEN LL + G + L D GL Sbjct: 179 EEDVKFYLAELALGLDHLHSLGIIYRDLKPENILLDEEG-----HIKLTDFGL------- 226 Query: 1059 SSGQHVDYDQRPDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQG 1238 S + +D++++ F GT+ Y + + S D S + +L G LP+QG Sbjct: 227 -SKEAIDHEKKAYSFCGTVEYMAPEVVNRQGHSHSADWWSYGVLMFEMLTGSLPFQGKDR 285 Query: 1239 DNKSFLVCKKKMSI 1280 L+ K K+ + Sbjct: 286 KETMTLILKAKLGM 299
>O34507:PRKC_BACSU Serine/threonine-protein kinase prkC - Bacillus subtilis| Length = 648 Score = 58.5 bits (140), Expect = 1e-07 Identities = 53/223 (23%), Positives = 95/223 (42%) Frame = +3 Query: 561 SPQYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQV 740 S +Y++ R +G GG VY+ + E A ++ L+F++ N E Q Sbjct: 8 SGRYQILRVIGGGGMANVYLAEDIILDREV----AIKI-LRFDYANDNEFIRRFRREAQS 62 Query: 741 YSSLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISI 920 SSL+ I ++ G + D Y +VM+ + + + + P I + +S Sbjct: 63 ASSLDHP-NIVSIYDLGEEDDIYYIVMEYVEGMTLKEYITANGPLHPKEALNIMEQIVSA 121 Query: 921 LEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDI 1100 + H VH D+KP N L+ G+ + + D G+A+ T+ + Sbjct: 122 IAHAHQNQIVHRDIKPHNILIDHMGN-----IKVTDFGIATALSSTTI-------THTNS 169 Query: 1101 FRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQG 1229 G++ Y S G +++ D+ +L L LL GR+P+ G Sbjct: 170 VLGSVHYLSPEQARGGLATKKSDIYALGIVLFELLTGRIPFDG 212
>P67999:KS6B1_RAT Ribosomal protein S6 kinase beta-1 - Rattus norvegicus (Rat)| Length = 525 Score = 58.5 bits (140), Expect = 1e-07 Identities = 70/269 (26%), Positives = 115/269 (42%), Gaps = 4/269 (1%) Frame = +3 Query: 498 EKIGGGEDDASPVPEKVQVGHSPQ-YKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEV 674 EK E + PEK++ P+ +++ R LGKGG+G+V+ R+V+G TG Sbjct: 70 EKFEISETSVNRGPEKIR----PECFELLRVLGKGGYGKVFQVRKVTGAN--TGKIFAMK 123 Query: 675 ALKFEH--RNSKGCNYGPPYEWQVYSSLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWD 848 LK RN+K + E + + + + ++ G Y+++ + G L+ Sbjct: 124 VLKKAMIVRNAKDTAHTKA-ERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFM 182 Query: 849 VWNSLGQTMTPSMVACIAVEAISI-LEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLI 1025 G M + AC + IS+ L LH KG ++ D+KPEN +L G + L Sbjct: 183 QLEREGIFMEDT--ACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQG-----HVKLT 235 Query: 1026 DLGLASKWKETSSGQHVDYDQRPDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLL 1205 D GL + + H F GTI Y + + +R D SL + +L Sbjct: 236 DFGLCKESIHDGTVTHT--------FCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDML 287 Query: 1206 RGRLPWQGYQGDNKSFLVCKKKMSISPDL 1292 G P+ G + K K+++ P L Sbjct: 288 TGAPPFTGENRKKTIDKILKCKLNLPPYL 316
>P67998:KS6B1_RABIT Ribosomal protein S6 kinase beta-1 - Oryctolagus cuniculus (Rabbit)| Length = 525 Score = 58.5 bits (140), Expect = 1e-07 Identities = 70/269 (26%), Positives = 115/269 (42%), Gaps = 4/269 (1%) Frame = +3 Query: 498 EKIGGGEDDASPVPEKVQVGHSPQ-YKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEV 674 EK E + PEK++ P+ +++ R LGKGG+G+V+ R+V+G TG Sbjct: 70 EKFEISETSVNRGPEKIR----PECFELLRVLGKGGYGKVFQVRKVTGAN--TGKIFAMK 123 Query: 675 ALKFEH--RNSKGCNYGPPYEWQVYSSLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWD 848 LK RN+K + E + + + + ++ G Y+++ + G L+ Sbjct: 124 VLKKAMIVRNAKDTAHTKA-ERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFM 182 Query: 849 VWNSLGQTMTPSMVACIAVEAISI-LEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLI 1025 G M + AC + IS+ L LH KG ++ D+KPEN +L G + L Sbjct: 183 QLEREGIFMEDT--ACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQG-----HVKLT 235 Query: 1026 DLGLASKWKETSSGQHVDYDQRPDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLL 1205 D GL + + H F GTI Y + + +R D SL + +L Sbjct: 236 DFGLCKESIHDGTVTHT--------FCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDML 287 Query: 1206 RGRLPWQGYQGDNKSFLVCKKKMSISPDL 1292 G P+ G + K K+++ P L Sbjct: 288 TGAPPFTGENRKKTIDKILKCKLNLPPYL 316
>Q8BSK8:KS6B1_MOUSE Ribosomal protein S6 kinase beta-1 - Mus musculus (Mouse)| Length = 525 Score = 58.5 bits (140), Expect = 1e-07 Identities = 70/269 (26%), Positives = 115/269 (42%), Gaps = 4/269 (1%) Frame = +3 Query: 498 EKIGGGEDDASPVPEKVQVGHSPQ-YKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEV 674 EK E + PEK++ P+ +++ R LGKGG+G+V+ R+V+G TG Sbjct: 70 EKFEISETSVNRGPEKIR----PECFELLRVLGKGGYGKVFQVRKVTGAN--TGKIFAMK 123 Query: 675 ALKFEH--RNSKGCNYGPPYEWQVYSSLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWD 848 LK RN+K + E + + + + ++ G Y+++ + G L+ Sbjct: 124 VLKKAMIVRNAKDTAHTKA-ERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFM 182 Query: 849 VWNSLGQTMTPSMVACIAVEAISI-LEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLI 1025 G M + AC + IS+ L LH KG ++ D+KPEN +L G + L Sbjct: 183 QLEREGIFMEDT--ACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQG-----HVKLT 235 Query: 1026 DLGLASKWKETSSGQHVDYDQRPDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLL 1205 D GL + + H F GTI Y + + +R D SL + +L Sbjct: 236 DFGLCKESIHDGTVTHT--------FCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDML 287 Query: 1206 RGRLPWQGYQGDNKSFLVCKKKMSISPDL 1292 G P+ G + K K+++ P L Sbjct: 288 TGAPPFTGENRKKTIDKILKCKLNLPPYL 316
>P23443:KS6B1_HUMAN Ribosomal protein S6 kinase beta-1 - Homo sapiens (Human)| Length = 525 Score = 58.5 bits (140), Expect = 1e-07 Identities = 70/269 (26%), Positives = 115/269 (42%), Gaps = 4/269 (1%) Frame = +3 Query: 498 EKIGGGEDDASPVPEKVQVGHSPQ-YKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEV 674 EK E + PEK++ P+ +++ R LGKGG+G+V+ R+V+G TG Sbjct: 70 EKFEISETSVNRGPEKIR----PECFELLRVLGKGGYGKVFQVRKVTGAN--TGKIFAMK 123 Query: 675 ALKFEH--RNSKGCNYGPPYEWQVYSSLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWD 848 LK RN+K + E + + + + ++ G Y+++ + G L+ Sbjct: 124 VLKKAMIVRNAKDTAHTKA-ERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFM 182 Query: 849 VWNSLGQTMTPSMVACIAVEAISI-LEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLI 1025 G M + AC + IS+ L LH KG ++ D+KPEN +L G + L Sbjct: 183 QLEREGIFMEDT--ACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQG-----HVKLT 235 Query: 1026 DLGLASKWKETSSGQHVDYDQRPDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLL 1205 D GL + + H F GTI Y + + +R D SL + +L Sbjct: 236 DFGLCKESIHDGTVTHT--------FCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDML 287 Query: 1206 RGRLPWQGYQGDNKSFLVCKKKMSISPDL 1292 G P+ G + K K+++ P L Sbjct: 288 TGAPPFTGENRKKTIDKILKCKLNLPPYL 316
>Q6TJY3:KS6B1_BOVIN Ribosomal protein S6 kinase beta-1 - Bos taurus (Bovine)| Length = 527 Score = 58.5 bits (140), Expect = 1e-07 Identities = 70/269 (26%), Positives = 115/269 (42%), Gaps = 4/269 (1%) Frame = +3 Query: 498 EKIGGGEDDASPVPEKVQVGHSPQ-YKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEV 674 EK E + PEK++ P+ +++ R LGKGG+G+V+ R+V+G TG Sbjct: 70 EKFEISETSVNRGPEKIR----PECFELLRVLGKGGYGKVFQVRKVTGAN--TGKIFAMK 123 Query: 675 ALKFEH--RNSKGCNYGPPYEWQVYSSLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWD 848 LK RN+K + E + + + + ++ G Y+++ + G L+ Sbjct: 124 VLKKAMIVRNAKDTAHTKA-ERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFM 182 Query: 849 VWNSLGQTMTPSMVACIAVEAISI-LEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLI 1025 G M + AC + IS+ L LH KG ++ D+KPEN +L G + L Sbjct: 183 QLEREGIFMEDT--ACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQG-----HVKLT 235 Query: 1026 DLGLASKWKETSSGQHVDYDQRPDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLL 1205 D GL + + H F GTI Y + + +R D SL + +L Sbjct: 236 DFGLCKESIHDGTVTHT--------FCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDML 287 Query: 1206 RGRLPWQGYQGDNKSFLVCKKKMSISPDL 1292 G P+ G + K K+++ P L Sbjct: 288 TGAPPFTGENRKKTIDKILKCKLNLPPYL 316
>Q15418:KS6A1_HUMAN Ribosomal protein S6 kinase alpha-1 - Homo sapiens (Human)| Length = 735 Score = 58.2 bits (139), Expect = 2e-07 Identities = 63/252 (25%), Positives = 107/252 (42%), Gaps = 5/252 (1%) Frame = +3 Query: 540 EKVQVGHSPQYKVERKLGKGGFGQVYVGRRVSGGTERTGPDA---YEVALKFEHRNSKGC 710 EK H KV LG+G FG+V++ R+V T PD+ Y + + + Sbjct: 55 EKADPSHFELLKV---LGQGSFGKVFLVRKV------TRPDSGHLYAMKVLKKATLKVRD 105 Query: 711 NYGPPYEWQVYSSLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTM--TPS 884 E + + +N + + +HY + L++D L D++ L + + T Sbjct: 106 RVRTKMERDILADVNHPFVVK-LHYAFQTEGKLYLILDFLRGG--DLFTRLSKEVMFTEE 162 Query: 885 MVACIAVEAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSS 1064 V E L+ LH+ G ++ D+KPEN LL + G + L D GL S Sbjct: 163 DVKFYLAELALGLDHLHSLGIIYRDLKPENILLDEEG-----HIKLTDFGL--------S 209 Query: 1065 GQHVDYDQRPDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDN 1244 + +D++++ F GT+ Y + + S D S + +L G LP+QG Sbjct: 210 KEAIDHEKKAYSFCGTVEYMAPEVVNRQGHSHSADWWSYGVLMFEMLTGSLPFQGKDRKE 269 Query: 1245 KSFLVCKKKMSI 1280 L+ K K+ + Sbjct: 270 TMTLILKAKLGM 281
>P54742:AFSK_STRGR Serine/threonine protein kinase afsK - Streptomyces griseus| Length = 807 Score = 58.2 bits (139), Expect = 2e-07 Identities = 66/252 (26%), Positives = 103/252 (40%), Gaps = 7/252 (2%) Frame = +3 Query: 558 HSPQ----YKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALK--FEHRNSKGCNYG 719 H P+ ++V +LG GG G VY+ R SG E+A F R ++ Sbjct: 8 HDPRRIGPFEVLGRLGAGGMGLVYLARSASGRRVAIKTVRTELAEDQLFRVRFTR----- 62 Query: 720 PPYEWQVYSSLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACI 899 E + +++G Y V R ++ + PSL ++ N G T + V + Sbjct: 63 ---EVEAARAVSGFYTAAVVDADPRAAVPWLATAYVPAPSLEEIVNECGPMPTQA-VRWL 118 Query: 900 AVEAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVD 1079 A L+ +H G VH D+KP N L+ + G +ID G+AS T Sbjct: 119 AAGIAQALQSIHGAGLVHRDLKPSNVLVVEDGPR------VIDFGIASGVSNTRL----- 167 Query: 1080 YDQRPDIFRGTIRYAS-VHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNKSFL 1256 ++ GT Y S A R+ + D+ SL TL+F G P+ G F+ Sbjct: 168 --TMTNVAVGTPAYMSPEQARDSRSVTGASDIFSLGSTLVFAATGHAPFHGANPVETVFM 225 Query: 1257 VCKKKMSISPDL 1292 + ++ PDL Sbjct: 226 LVRE----GPDL 233
>Q02595:KPK2_PLAFK Probable serine/threonine-protein kinase 2 - Plasmodium falciparum| (isolate K1 / Thailand) Length = 510 Score = 57.4 bits (137), Expect = 3e-07 Identities = 50/165 (30%), Positives = 76/165 (46%), Gaps = 1/165 (0%) Frame = +3 Query: 552 VGHSPQYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYE 731 +G Y + +K+GKG F Y+G + G V +K E SK E Sbjct: 105 LGFKNVYVLNKKIGKGSFSTAYIGTNILYGNR--------VVVK-EVDKSKVKESNVYTE 155 Query: 732 WQVYSSLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEA 911 +V + Y I + ++G Y+++ + G L++ N+ G VA A++ Sbjct: 156 IEVLRKVMHKYIIKLISAYEQEGFVYLVLEYLKGGELFEYLNNNGPYT--EQVAKKAMKR 213 Query: 912 ISI-LEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLAS 1043 + I LE LH+ G VH D+K EN +L P P K +ID GLAS Sbjct: 214 VLIALEALHSNGVVHRDLKMENLMLENPNDPSSLK--IIDFGLAS 256
>P10666:KS6AB_XENLA Ribosomal protein S6 kinase 2 beta - Xenopus laevis (African clawed| frog) Length = 629 Score = 56.6 bits (135), Expect = 5e-07 Identities = 63/252 (25%), Positives = 110/252 (43%), Gaps = 5/252 (1%) Frame = +3 Query: 540 EKVQVGHSPQYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEV-ALKFEHRNSKGCN- 713 EK H KV LG+G FG+V++ R++ T PDA ++ A+K + + Sbjct: 55 EKADQSHFVLLKV---LGQGSFGKVFLVRKI------TPPDANQLYAMKVLKKATLKVRD 105 Query: 714 -YGPPYEWQVYSSLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTM--TPS 884 E + + ++ + + +HY + L++D L D++ L + + T Sbjct: 106 RVRTKMERDILADVHHPFVVR-LHYAFQTEGKLYLILDFLRGG--DLFTRLSKEVMFTEE 162 Query: 885 MVACIAVEAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSS 1064 V E L+ LH+ G ++ D+KPEN LL + G + L D GL S Sbjct: 163 DVKFYLAELALGLDHLHSLGIIYRDLKPENILLDEEG-----HIKLTDFGL--------S 209 Query: 1065 GQHVDYDQRPDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDN 1244 + +D++++ F GT+ Y + + S D S + +L G LP+QG Sbjct: 210 KEAIDHEKKAYSFCGTVEYMAPEVVNRQGHSHGADWWSYGVLMFEMLTGSLPFQGKDRKE 269 Query: 1245 KSFLVCKKKMSI 1280 L+ K K+ + Sbjct: 270 TMTLILKAKLGM 281
>Q63531:KS6A1_RAT Ribosomal protein S6 kinase alpha-1 - Rattus norvegicus (Rat)| Length = 735 Score = 56.2 bits (134), Expect = 7e-07 Identities = 62/252 (24%), Positives = 106/252 (42%), Gaps = 5/252 (1%) Frame = +3 Query: 540 EKVQVGHSPQYKVERKLGKGGFGQVYVGRRVSGGTERTGPD---AYEVALKFEHRNSKGC 710 EK H KV LG+G FG+V++ R+V T PD Y + + + Sbjct: 55 EKADPSHFELLKV---LGQGSFGKVFLVRKV------TRPDNGHLYAMKVLKKATLKVRD 105 Query: 711 NYGPPYEWQVYSSLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTM--TPS 884 E + + +N + + +HY + L++D L D++ L + + T Sbjct: 106 RVRTKMERDILADVNHPFVVK-LHYAFQTEGKLYLILDFLRGG--DLFTRLSKEVMFTEE 162 Query: 885 MVACIAVEAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSS 1064 V E L+ LH+ G ++ D+KPEN LL + G + L D GL S Sbjct: 163 DVKFYLAELALGLDHLHSLGIIYRDLKPENILLDEEG-----HIKLTDFGL--------S 209 Query: 1065 GQHVDYDQRPDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDN 1244 + +D++++ F GT+ Y + + + D S + +L G LP+QG Sbjct: 210 KEAIDHEKKAYSFCGTVEYMAPEVVNRQGHTHSADWWSYGVLMFEMLTGSLPFQGKDRKE 269 Query: 1245 KSFLVCKKKMSI 1280 L+ K K+ + Sbjct: 270 TMTLILKAKLGM 281
>P10665:KS6AA_XENLA Ribosomal protein S6 kinase 2 alpha - Xenopus laevis (African clawed| frog) Length = 733 Score = 55.8 bits (133), Expect = 9e-07 Identities = 60/254 (23%), Positives = 111/254 (43%), Gaps = 5/254 (1%) Frame = +3 Query: 534 VPEKVQVGHSPQYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEV-ALKFEHRNSKGC 710 V E + + + + LG+G FG+V++ R++ T PDA ++ A+K + + Sbjct: 50 VKEGSEKADQSDFVLLKVLGQGSFGKVFLVRKI------TPPDANQLYAMKVLKKATLKV 103 Query: 711 N--YGPPYEWQVYSSLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTM--T 878 E + + ++ + + +HY + L++D L D++ L + + T Sbjct: 104 RDRVRTKMERDILADVHHPFVVR-LHYAFQTEGKLYLILDFLRGG--DLFTRLSKEVMFT 160 Query: 879 PSMVACIAVEAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKET 1058 V E L+ LH+ G ++ D+KPEN LL + G + L D GL Sbjct: 161 EEDVKFYLAELALGLDHLHSLGIIYRDLKPENILLDEEG-----HIKLTDFGL------- 208 Query: 1059 SSGQHVDYDQRPDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQG 1238 S + +D++++ F GT+ Y + + S D S + +L G LP+QG Sbjct: 209 -SKEAIDHEKKAYSFCGTVEYMAPEVVNRQGHSHSADWWSYGVLMFEMLTGSLPFQGKDR 267 Query: 1239 DNKSFLVCKKKMSI 1280 L+ K K+ + Sbjct: 268 KETMTLILKAKLGM 281
>P38070:KBN8_YEAST Probable serine/threonine-protein kinase YBR028C - Saccharomyces| cerevisiae (Baker's yeast) Length = 525 Score = 55.8 bits (133), Expect = 9e-07 Identities = 50/155 (32%), Positives = 70/155 (45%), Gaps = 2/155 (1%) Frame = +3 Query: 807 YVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISILEKLHAKGFVHGDVKPENFLLG 986 Y+L+ I G L+ G T+ + V+ A E L LH KG V+ D+KPEN LL Sbjct: 228 YLLLQYIPGGELFYHLKEHG-TLDETTVSFYAAEISCALRFLHTKGVVYRDLKPENCLLN 286 Query: 987 QPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFR--GTIRYASVHAHLGRTGSR 1160 Q G L L D GL+ K S+ D + ++ GT Y + LG+ S+ Sbjct: 287 QRG-----HLVLTDFGLSKKSANDSAVDEEDPENVNALYSIIGTPEYCAPEILLGKAYSQ 341 Query: 1161 RDDLESLAYTLIFLLRGRLPWQGYQGDNKSFLVCK 1265 D SL L +L G+ P Y G N ++ K Sbjct: 342 NCDWYSLGCLLYDMLVGKPP---YTGSNHKVIINK 373
>P72003:PKNF_MYCTU Probable serine/threonine-protein kinase pknF - Mycobacterium| tuberculosis Length = 476 Score = 55.1 bits (131), Expect = 2e-06 Identities = 77/329 (23%), Positives = 128/329 (38%), Gaps = 7/329 (2%) Frame = +3 Query: 570 YKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYSS 749 + + R+LG GG G+VY+ R DA +V S Y + + ++ Sbjct: 12 FTIVRQLGSGGMGEVYLARH----PRLPRQDALKV---LRADVSADGEYRARFNREADAA 64 Query: 750 LNGCYG-IPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISI-- 920 + + I VH +G + MD + + D + L M E I+ Sbjct: 65 ASLWHPHIVAVHDRGEFDGQLWIDMDFVDGT--DTVSLLRDRYPNGMPGPEVTEIITAVA 122 Query: 921 --LEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRP 1094 L+ H + +H DVKP N L+ P SPD +++ L D G+A W + SG Sbjct: 123 EALDYAHERRLLHRDVKPANILIANPDSPD-RRIMLADFGIAG-WVDDPSGL-----TAT 175 Query: 1095 DIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNKSFLVCKKKM 1274 ++ GT+ YA+ +G R D +LA T LL G P+Q +V + + Sbjct: 176 NMTVGTVSYAAPEQLMGNELDGRADQYALAATAFHLLTGSPPFQ----HANPAVVISQHL 231 Query: 1275 SISPDLMCCYCAPPFKLFLETVTNMKFDEEPNYPKLISLFDELI--EPQHLRPIRIDGAL 1448 S SP + D P L +F + + +P+ +D A Sbjct: 232 SASPPAI-------------------GDRVPELTPLDPVFAKALAKQPKDRYQRCVDFAR 272 Query: 1449 KAGQKRGRVSHEEDEQPRKKVRLGSPANQ 1535 G + G +D + + V + +PA + Sbjct: 273 ALGHRLGGAGDPDDTRVSQPVAVAAPAKR 301
>Q7TZN1:PKNF_MYCBO Probable serine/threonine-protein kinase pknF - Mycobacterium bovis| Length = 476 Score = 55.1 bits (131), Expect = 2e-06 Identities = 77/329 (23%), Positives = 128/329 (38%), Gaps = 7/329 (2%) Frame = +3 Query: 570 YKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYSS 749 + + R+LG GG G+VY+ R DA +V S Y + + ++ Sbjct: 12 FTIVRQLGSGGMGEVYLARH----PRLPRQDALKV---LRADVSADGEYRARFNREADAA 64 Query: 750 LNGCYG-IPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISI-- 920 + + I VH +G + MD + + D + L M E I+ Sbjct: 65 ASLWHPHIVAVHDRGEFDGQLWIDMDFVDGT--DTVSLLRDRYPNGMPGPEVTEIITAVA 122 Query: 921 --LEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRP 1094 L+ H + +H DVKP N L+ P SPD +++ L D G+A W + SG Sbjct: 123 EALDYAHERRLLHRDVKPANILIANPDSPD-RRIMLADFGIAG-WVDDPSGL-----TAT 175 Query: 1095 DIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNKSFLVCKKKM 1274 ++ GT+ YA+ +G R D +LA T LL G P+Q +V + + Sbjct: 176 NMTVGTVSYAAPEQLMGNELDGRADQYALAATAFHLLTGSPPFQ----HANPAVVISQHL 231 Query: 1275 SISPDLMCCYCAPPFKLFLETVTNMKFDEEPNYPKLISLFDELI--EPQHLRPIRIDGAL 1448 S SP + D P L +F + + +P+ +D A Sbjct: 232 SASPPAI-------------------GDRVPELTPLDPVFAKALAKQPKDRYQRCVDFAR 272 Query: 1449 KAGQKRGRVSHEEDEQPRKKVRLGSPANQ 1535 G + G +D + + V + +PA + Sbjct: 273 ALGHRLGGAGDPDDTRVSQPVAVAAPAKR 301
>P54741:AFSK_STRCO Serine/threonine protein kinase afsK - Streptomyces coelicolor| Length = 799 Score = 54.7 bits (130), Expect = 2e-06 Identities = 65/252 (25%), Positives = 101/252 (40%), Gaps = 7/252 (2%) Frame = +3 Query: 558 HSPQ----YKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALK--FEHRNSKGCNYG 719 H P+ ++V +LG GG G VY+ R SG E+A F R ++ Sbjct: 8 HDPRRIGPFEVLGRLGAGGMGLVYLARSASGRRVAIKTVRTELAEDQLFRVRFTR----- 62 Query: 720 PPYEWQVYSSLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACI 899 E + +++G Y V R ++ + PSL ++ N G M V + Sbjct: 63 ---EVEAARAVSGFYTAAVVDADPRAAVPWLATAYVPAPSLEEIVNECGP-MPAQAVRWL 118 Query: 900 AVEAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVD 1079 A L+ +H G VH D+KP N L+ + G +ID G+AS T Sbjct: 119 AAGVAEALQSIHGAGLVHRDLKPSNVLVVEDGPR------VIDFGIASGVSNTRL----- 167 Query: 1080 YDQRPDIFRGTIRYAS-VHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNKSFL 1256 ++ GT Y S A R+ + D+ SL L+F G P+ G F+ Sbjct: 168 --TMTNVAVGTPAYMSPEQAKDSRSVTGASDVFSLGSMLVFAATGHPPFHGANPVETVFM 225 Query: 1257 VCKKKMSISPDL 1292 + ++ PDL Sbjct: 226 LLRE----GPDL 233
>Q11053:PKNH_MYCTU Probable serine/threonine-protein kinase pknH - Mycobacterium| tuberculosis Length = 626 Score = 54.3 bits (129), Expect = 3e-06 Identities = 65/245 (26%), Positives = 98/245 (40%), Gaps = 6/245 (2%) Frame = +3 Query: 570 YKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKF---EHRNSKGCNYGPPYEWQV 740 Y ++R LG+GG G+VY E T + + VA+K E E ++ Sbjct: 16 YHLKRLLGRGGMGEVYEA-------EHTVKE-WTVAVKLMTAEFSKDPVFRERMKREARI 67 Query: 741 YSSLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISI 920 L + +P Y G ++ + + G L V G +TP I + S Sbjct: 68 AGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGP-LTPPRAVAIITQIASA 126 Query: 921 LEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKW---KETSSGQHVDYDQR 1091 L+ HA G +H DVKP+N L+ + + +L+D G+AS K T G V Sbjct: 127 LDAAHADGVMHRDVKPQNILITR-----DDFAYLVDFGIASATTDEKLTQLGTAV----- 176 Query: 1092 PDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNKSFLVCKKK 1271 GT +Y + + R D+ +LA L L G P Y+ D+ LV Sbjct: 177 -----GTWKYMAPERFSNDEVTYRADIYALACVLHECLTGAPP---YRADSAGTLVSSHL 228 Query: 1272 MSISP 1286 M P Sbjct: 229 MGPIP 233
>Q7U095:PKNH_MYCBO Probable serine/threonine-protein kinase pknH - Mycobacterium bovis| Length = 596 Score = 54.3 bits (129), Expect = 3e-06 Identities = 65/245 (26%), Positives = 98/245 (40%), Gaps = 6/245 (2%) Frame = +3 Query: 570 YKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKF---EHRNSKGCNYGPPYEWQV 740 Y ++R LG+GG G+VY E T + + VA+K E E ++ Sbjct: 16 YHLKRLLGRGGMGEVYEA-------EHTVKE-WTVAVKLMTAEFSKDPVFRERMKREARI 67 Query: 741 YSSLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISI 920 L + +P Y G ++ + + G L V G +TP I + S Sbjct: 68 AGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGP-LTPPRAVAIITQIASA 126 Query: 921 LEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKW---KETSSGQHVDYDQR 1091 L+ HA G +H DVKP+N L+ + + +L+D G+AS K T G V Sbjct: 127 LDAAHADGVMHRDVKPQNILITR-----DDFAYLVDFGIASATTDEKLTQLGTAV----- 176 Query: 1092 PDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNKSFLVCKKK 1271 GT +Y + + R D+ +LA L L G P Y+ D+ LV Sbjct: 177 -----GTWKYMAPERFSNDEVTYRADIYALACVLHECLTGAPP---YRADSAGTLVSSHL 228 Query: 1272 MSISP 1286 M P Sbjct: 229 MGPIP 233
>P38147:CHK1_YEAST Serine/threonine-protein kinase CHK1 - Saccharomyces cerevisiae| (Baker's yeast) Length = 527 Score = 54.3 bits (129), Expect = 3e-06 Identities = 38/120 (31%), Positives = 58/120 (48%), Gaps = 3/120 (2%) Frame = +3 Query: 906 EAISILEKLHAK-GFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDY 1082 + +S + LH + G H D+KPEN LL + G+ L L D GLAS+++ V Sbjct: 124 QLVSAINYLHVECGVAHRDIKPENILLDKNGN-----LKLADFGLASQFRRKDGTLRVSM 178 Query: 1083 DQR--PDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNKSFL 1256 DQR P + Y+ + RT D+ S+ L LL G+ PW+ +N+ F+ Sbjct: 179 DQRGSPPYMAPEVLYSEEGYYADRT-----DIWSIGILLFVLLTGQTPWELPSLENEDFV 233
>O00311:CDC7_HUMAN Cell division cycle 7-related protein kinase - Homo sapiens (Human)| Length = 574 Score = 54.3 bits (129), Expect = 3e-06 Identities = 57/188 (30%), Positives = 83/188 (44%), Gaps = 2/188 (1%) Frame = +3 Query: 501 KIGGGEDDASPVPEKVQVGHSPQYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVAL 680 K+ G + D + E V S +K+E K+G+G F VY+ + GP+ ++AL Sbjct: 36 KLAGVKKDIEKLYEAVPQ-LSNVFKIEDKIGEGTFSSVYLAT----AQLQVGPEE-KIAL 89 Query: 681 KFEHRNSKGCNYGPPYEWQVYSSLNGCYGIPWVHYKGRQGDYYVLVMDILG-PSLWDVWN 857 K S E Q + G + V Y R+ D+ V+ M L S D+ N Sbjct: 90 KHLIPTSHPIRIAA--ELQCLTVAGGQDNVMGVKYCFRKNDHVVIAMPYLEHESFLDILN 147 Query: 858 SLG-QTMTPSMVACIAVEAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLG 1034 SL Q + M+ L+++H G VH DVKP NFL + KK L+D G Sbjct: 148 SLSFQEVREYML-----NLFKALKRIHQFGIVHRDVKPSNFLYNR----RLKKYALVDFG 198 Query: 1035 LASKWKET 1058 LA +T Sbjct: 199 LAQGTHDT 206
>Q01389:BCK1_YEAST Serine/threonine-protein kinase BCK1/SLK1/SSP31 - Saccharomyces| cerevisiae (Baker's yeast) Length = 1478 Score = 53.9 bits (128), Expect = 3e-06 Identities = 65/297 (21%), Positives = 127/297 (42%), Gaps = 5/297 (1%) Frame = +3 Query: 588 LGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYS--SLNGC 761 +GKG FG VY+ V+ G E EV K+ +N + +V + L+ Sbjct: 1181 IGKGSFGAVYLCLNVTTG-EMMAVKQVEVP-KYSSQNEAILSTVEALRSEVSTLKDLDHL 1238 Query: 762 YGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISILEKLHAK 941 + ++ ++ + Y + + + G S+ + G+ P ++ + + + L LH+K Sbjct: 1239 NIVQYLGFENKNNIYSLFLEYVAGGSVGSLIRMYGRFDEP-LIKHLTTQVLKGLAYLHSK 1297 Query: 942 GFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFRGTIRY 1121 G +H D+K +N LL Q G + D G++ K K+ Y RGT+ + Sbjct: 1298 GILHRDMKADNLLLDQDGI-----CKISDFGISRKSKDI-------YSNSDMTMRGTVFW 1345 Query: 1122 ASVHAHLGRTG-SRRDDLESLAYTLIFLLRGRLPWQGYQGDNKSFLVCKKKMSIS-PDLM 1295 + + G S + D+ SL ++ + G+ PW + F + K K + P+ Sbjct: 1346 MAPEMVDTKQGYSAKVDIWSLGCIVLEMFAGKRPWSNLEVVAAMFKIGKSKSAPPIPEDT 1405 Query: 1296 CCYCAPPFKLFLETVTNMKFDEEPNYPKLIS-LFDELIEPQHLRPIRIDGALKAGQK 1463 + + FL+ + ++ P +L+S F E+ E + + R+ +K+ K Sbjct: 1406 LPLISQIGRNFLDACFEINPEKRPTANELLSHPFSEVNETFNFKSTRLAKFIKSNDK 1462
>P38938:CEK1_SCHPO Serine/threonine-protein kinase cek1 - Schizosaccharomyces pombe| (Fission yeast) Length = 1338 Score = 53.5 bits (127), Expect = 4e-06 Identities = 44/159 (27%), Positives = 71/159 (44%), Gaps = 2/159 (1%) Frame = +3 Query: 570 YKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVA-LKFEHRNSKGCNYGPPYEWQVYS 746 YK+ + + KG FG VY+ ++ RT D + + LK + +K E + Sbjct: 589 YKILKPISKGAFGSVYLAQK------RTTGDYFAIKILKKSNMIAKNQVINVRAERAILM 642 Query: 747 SLNGCYGIPWVHYKGRQGDYYVLVMDIL-GPSLWDVWNSLGQTMTPSMVACIAVEAISIL 923 S + ++Y + DY LVM+ L G + ++G + + E + L Sbjct: 643 SQGESPFVAKLYYTFQSKDYLYLVMEYLNGGDCGSLLKTMG-VLDLDWIRTYIAETVLCL 701 Query: 924 EKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLA 1040 LH +G +H D+KPEN L+ Q G L L D GL+ Sbjct: 702 GDLHDRGIIHRDIKPENLLISQNG-----HLKLTDFGLS 735
>O05871:PKND_MYCTU Serine/threonine-protein kinase pknD - Mycobacterium tuberculosis| Length = 664 Score = 53.1 bits (126), Expect = 6e-06 Identities = 65/245 (26%), Positives = 98/245 (40%), Gaps = 6/245 (2%) Frame = +3 Query: 570 YKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKF---EHRNSKGCNYGPPYEWQV 740 Y++ R LG+GG G+VY E T VALK ++ ++ E Sbjct: 15 YQLLRLLGRGGMGEVYEA-------EDTRKHRV-VALKLISPQYSDNAVFRARMQREADT 66 Query: 741 YSSLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISI 920 L + +P Y G ++V + I G SL + G +TP+ I + + Sbjct: 67 AGRLTEPHIVPIHDYGEINGQFFVEMRMIDGTSLRALLKQYGP-LTPARAVAIVRQIAAA 125 Query: 921 LEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKE---TSSGQHVDYDQR 1091 L+ HA G H DVKPEN L+ +L+D G+A + T +G V Sbjct: 126 LDAAHANGVTHRDVKPENILV-----TASDFAYLVDFGIARAASDPGLTQTGTAV----- 175 Query: 1092 PDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNKSFLVCKKK 1271 GT Y + G + R D+ +LA L L G P Y+ D+ L+ Sbjct: 176 -----GTYNYMAPERFTGDEVTYRADIYALACVLGECLTGAPP---YRADSVERLIAAHL 227 Query: 1272 MSISP 1286 M +P Sbjct: 228 MDPAP 232
>P28178:PK2_DICDI Protein kinase 2 - Dictyostelium discoideum (Slime mold)| Length = 479 Score = 53.1 bits (126), Expect = 6e-06 Identities = 77/303 (25%), Positives = 117/303 (38%), Gaps = 13/303 (4%) Frame = +3 Query: 492 SPEKIGGGEDDASPVPEKVQVGHSPQ------YKVERKLGKGGFGQVYVGRRVSGGTERT 653 SP G G DD PE+V + Q +++ +GKG FG+V ++ Sbjct: 121 SPNGSGNGNDDEDEGPEEVIFSKNKQSATKDDFELLNVIGKGSFGKVMQ-------VKKK 173 Query: 654 GPD---AYEVALKFEHRNSKGCNYGPPYEWQVYSSLNGCYGIPWV---HYKGRQGDYYVL 815 G D A +V K K N+ + ++ C P++ HY + D + Sbjct: 174 GEDKIFAMKVLRKDAIIARKQVNHTKSEK-----TILQCISHPFIVNLHYAFQTKDKLYM 228 Query: 816 VMDIL-GPSLWDVWNSLGQTMTPSMVACIAVEAISILEKLHAKGFVHGDVKPENFLLGQP 992 V+D + G L+ G+ P V A E +S L+ LH + V+ D+KPEN LL Sbjct: 229 VLDFVNGGELFFHLKREGRFSEPR-VKIYAAEIVSALDHLHKQDIVYRDLKPENILLDSE 287 Query: 993 GSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFRGTIRYASVHAHLGRTGSRRDDL 1172 G + + D GL SK ET+ G F GT Y + G D Sbjct: 288 G-----HICITDFGL-SKKIETTDGTFT--------FCGTPEYLAPEVLNGHGHGCAVDW 333 Query: 1173 ESLAYTLIFLLRGRLPWQGYQGDNKSFLVCKKKMSISPDLMCCYCAPPFKLFLETVTNMK 1352 SL L +L G P+ + ++ I Y +P K LE + + Sbjct: 334 WSLGTLLYEMLTGLPPFYSQNVSTMYQKILNGELKIP-----TYISPEAKSLLEGLLTRE 388 Query: 1353 FDE 1361 D+ Sbjct: 389 VDK 391
>Q39030:KPK19_ARATH Serine/threonine-protein kinase AtPK19 - Arabidopsis thaliana| (Mouse-ear cress) Length = 471 Score = 53.1 bits (126), Expect = 6e-06 Identities = 66/279 (23%), Positives = 118/279 (42%), Gaps = 7/279 (2%) Frame = +3 Query: 453 EEFADKVVKMDGVS----PEKIGGGEDDASPVPEKVQ-VGHSPQYKVERKLGKGGFGQVY 617 E+ D V ++G S E G + D+ PE+V V ++V + +G+G FG+VY Sbjct: 96 EDSVDLVECVEGESIKENDEFSGNDDTDSEKSPEEVSGVVGIEDFEVLKVVGQGAFGKVY 155 Query: 618 VGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYSSLNGCYGIPWVHYKGRQ 797 R+ + + A +V K + Y E + + ++ + I + Y + Sbjct: 156 QVRK----KDTSEIYAMKVMRKDKIVEKNHAEYMKA-ERDILTKIDHPF-IVQLKYSFQT 209 Query: 798 GDYYVLVMDIL--GPSLWDVWNSLGQTMTPSMVACIAVEAISILEKLHAKGFVHGDVKPE 971 LV+D + G + +++ + E +S + LH KG +H D+KPE Sbjct: 210 KYRLYLVLDFINGGHLFFQLYHQ--GLFREDLARVYTAEIVSAVSHLHEKGIMHRDLKPE 267 Query: 972 NFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFRGTIRYASVHAHLGRT 1151 N L+ G + L D GLA +++E + R + GT Y + G+ Sbjct: 268 NILMDVDG-----HVMLTDFGLAKEFEENT---------RSNSMCGTTEYMAPEIVRGKG 313 Query: 1152 GSRRDDLESLAYTLIFLLRGRLPWQGYQGDNKSFLVCKK 1268 + D S+ L +L G+ P+ G +G + +V K Sbjct: 314 HDKAADWWSVGILLYEMLTGKPPFLGSKGKIQQKIVKDK 352
>Q9CEF5:PKNB_LACLA Probable serine/threonine-protein kinase pknB - Lactococcus lactis| subsp. lactis (Streptococcus lactis) Length = 627 Score = 52.8 bits (125), Expect = 8e-06 Identities = 48/232 (20%), Positives = 97/232 (41%), Gaps = 4/232 (1%) Frame = +3 Query: 546 VQVGH--SPQYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYG 719 +Q+G + +Y++ +++G+GG VY G G VA+K N + + Sbjct: 2 IQIGKIFADRYRIIKEIGRGGMANVYQGEDTFLGDRL-------VAIKVLRSNFENDDIA 54 Query: 720 -PPYEWQVYSSLNGCY-GIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVA 893 ++ + ++ + I + G +VM+ + + + + Sbjct: 55 IARFQREAFAMAELSHPNIVGISDVGEFESQQYIVMEFVDGMTLKQYINQNAPLANDEAI 114 Query: 894 CIAVEAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQH 1073 I E +S ++ H+ G +H D+KP+N L+ G+ + + D G+A ETS Q Sbjct: 115 EIITEILSAMDMAHSHGIIHRDLKPQNVLVSSSGT-----VKVTDFGIAKALSETSLTQ- 168 Query: 1074 VDYDQRPDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQG 1229 + G++ Y S G + + D+ ++ L LL G++P+ G Sbjct: 169 ------TNTMFGSVHYLSPEQARGSNATVQSDIYAIGIILFELLTGQIPFDG 214
>Q9XBQ0:PKN3_MYXXA Serine/threonine-protein kinase pkn3 - Myxococcus xanthus| Length = 547 Score = 52.8 bits (125), Expect = 8e-06 Identities = 53/221 (23%), Positives = 91/221 (41%), Gaps = 1/221 (0%) Frame = +3 Query: 567 QYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYS 746 +Y+VE +G+GG G+V+ R++S L E ++ E + S Sbjct: 17 KYRVEALIGEGGMGKVFRARQLSLDKVVVLKVLRHTLLSDERTVARFQR-----EAKAAS 71 Query: 747 SLNGCYGIPWVHY-KGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISIL 923 LN I + + + G ++ + + G L + S + V I + +S L Sbjct: 72 RLNHPNSISVLDFGQAEDGALFIAMEYVAGQDLHQIL-SREWPLNEGRVVRIVSQVLSAL 130 Query: 924 EKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIF 1103 H G +H D+KPEN ++ +P + + ++D G+A T G + R Sbjct: 131 SDAHGAGVIHRDLKPENIMV-EPRRNEPDFVKVLDFGIAKITDSTDDGPAL---TRAGFV 186 Query: 1104 RGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQ 1226 GT Y S G R DL ++ L L+ G LP++ Sbjct: 187 CGTPEYMSPEQARGSQLDHRSDLYAVGVILYQLMTGLLPFE 227
>Q8G4G1:PKNA2_BIFLO Probable serine/threonine-protein kinase pknA2 - Bifidobacterium| longum Length = 757 Score = 52.4 bits (124), Expect = 1e-05 Identities = 64/280 (22%), Positives = 104/280 (37%), Gaps = 13/280 (4%) Frame = +3 Query: 567 QYKVERKLGKGGFGQVY------VGRRVSGGTERT----GPDAYEVALKFEHRNSKGCNY 716 +Y++ R + +GG VY +GR V+ T GP + +F + + Sbjct: 13 RYRIVRNIAEGGMATVYEAIDERLGRTVAIKVMHTQLAKGPHREQFVERFRREANSAASI 72 Query: 717 GPPYEWQVYSSLNGCYGIPWVHYKGRQGDYYVLVMDIL-GPSLWDVWNSLGQTMTPSMVA 893 P+ QVY + G LVM+ + G +L N+ G T + Sbjct: 73 ANPHIVQVYDT-------------GEFNGLDFLVMEYVHGVNLRHEMNAQG-TFSVRETL 118 Query: 894 CIAVEAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQH 1073 + E + L H G VH D+KPEN L+ D + + D GLA + + Sbjct: 119 RVVAETLDGLASAHRAGVVHRDIKPENILIN-----DRGHVQITDFGLAKAASQATLSS- 172 Query: 1074 VDYDQRPDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNKSF 1253 + GT Y + + + DL S+ +L G++P + DN Sbjct: 173 ------TGMLLGTAAYLAPEMIENNQATAQGDLYSVGIMAWEMLTGKVP---FDSDNPVT 223 Query: 1254 LVCKKKMSISPDL--MCCYCAPPFKLFLETVTNMKFDEEP 1367 LV K P + +C P F+ +T + D P Sbjct: 224 LVFKHVHEDVPSVATVCQGIDPSVAAFIAHLTARQVDARP 263
>P42818:KPK1_ARATH Serine/threonine-protein kinase AtPK1/AtPK6 - Arabidopsis thaliana| (Mouse-ear cress) Length = 465 Score = 52.4 bits (124), Expect = 1e-05 Identities = 54/235 (22%), Positives = 99/235 (42%), Gaps = 2/235 (0%) Frame = +3 Query: 570 YKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYSS 749 ++V + +GKG FG+VY R+ + T ++ +H K E + + Sbjct: 134 FEVMKVVGKGAFGKVYQVRK-----KETSEIYAMKVMRKDHIMEKNHAEYMKAERDILTK 188 Query: 750 LNGCYGIPWVHYKGRQGDYYVLVMDIL--GPSLWDVWNSLGQTMTPSMVACIAVEAISIL 923 ++ + I + Y + LV+D + G + +++ + E +S + Sbjct: 189 IDHPF-IVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQ--GLFREDLARVYTAEIVSAV 245 Query: 924 EKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIF 1103 LH KG +H D+KPEN L+ G + L D GLA +++E + R + Sbjct: 246 SHLHEKGIMHRDLKPENILMDTDG-----HVMLTDFGLAKEFEENT---------RSNSM 291 Query: 1104 RGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNKSFLVCKK 1268 GT Y + G+ + D S+ L +L G+ P+ G +G + +V K Sbjct: 292 CGTTEYMAPEIVRGKGHDKAADWWSVGILLYEMLTGKPPFLGSKGKIQQKIVKDK 346
>Q8MYQ1:Y31E_CAEEL Putative serine/threonine-protein kinase F31E3.2 - Caenorhabditis| elegans Length = 441 Score = 52.0 bits (123), Expect = 1e-05 Identities = 61/224 (27%), Positives = 91/224 (40%), Gaps = 6/224 (2%) Frame = +3 Query: 570 YKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRN---SKGCNYGPPYEWQV 740 + +ER+LG+G FG VY + + A+K + + SK E + Sbjct: 126 FVLERQLGRGSFGVVYCASAIHDSERK-------FAIKMQEKREIISKRAVLQVKREASI 178 Query: 741 YSSLNGCYGIPWVHYKGRQGDY-YVLVMDILGPS--LWDVWNSLGQTMTPSMVACIAVEA 911 L I + + + Y L+ G + L+ VW G +++ + + I E Sbjct: 179 QRLLPSHPFIARTYSTWQTRTHLYSLLQYPTGSTGDLFSVWRQRG-SLSEAAIRLIGAEL 237 Query: 912 ISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQR 1091 S ++ LH ++ DVK EN +L Q G LID GLA K K+ SS Sbjct: 238 ASAIDFLHQNDVIYRDVKLENVVLDQWGHA-----LLIDFGLAKKLKQGSS--------- 283 Query: 1092 PDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPW 1223 GT++Y S G T S D SL L LL G P+ Sbjct: 284 TGTICGTLQYMSPDVASGGTYSHYVDWWSLGVLLHILLTGIYPY 327
>P54734:PKNA_ANASP Serine/threonine-protein kinase pknA - Anabaena sp. (strain PCC 7120)| Length = 564 Score = 52.0 bits (123), Expect = 1e-05 Identities = 60/233 (25%), Positives = 94/233 (40%), Gaps = 15/233 (6%) Frame = +3 Query: 567 QYKVERKLGKGGFGQVYVGRRVSGGTER-----------TGPDAYEVALKFEHRNSKGCN 713 +Y+V + LG GGFG+ ++ + R P Y++ + R Sbjct: 8 RYRVIKTLGSGGFGETFLAEDSQMPSNRRCVVKQLRPIHNNPQIYQLVQERFQR------ 61 Query: 714 YGPPYEWQVYSSLNGCYG-IPWVH-YKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSM 887 E + L G IP ++ Y +YV+ + G +L G ++ S Sbjct: 62 -----EAAILEDLGSYSGQIPTLYAYFQSNTQFYVVQEWVEGDTLTAKLKQQG-VLSESA 115 Query: 888 VACIAVEAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSG 1067 V I + + +LE +H+K +H D+KP+N +L + K LID G + S G Sbjct: 116 VRDILINLLPVLEYVHSKRIIHRDIKPDNIILRH----RDGKPVLIDFGAVRE----SMG 167 Query: 1068 QHVDYDQRP--DIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLP 1220 ++ P I GT Y GR DL SL T I+LL G+ P Sbjct: 168 TVINSQGNPTSSIVIGTPGYMPSEQAAGRP-VYSSDLYSLGLTAIYLLTGKQP 219
>Q7TZN3:PKNE_MYCBO Serine/threonine-protein kinase pknE - Mycobacterium bovis| Length = 566 Score = 51.6 bits (122), Expect = 2e-05 Identities = 61/235 (25%), Positives = 91/235 (38%), Gaps = 13/235 (5%) Frame = +3 Query: 570 YKVERKLGKGGFGQVY----------VGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYG 719 Y++ R +G+GG G VY V ++ T + PD + ++ E R + Sbjct: 16 YRLRRLVGRGGMGDVYEAEDTVRERIVALKLMSETLSSDPD-FRTRMQREARTA------ 68 Query: 720 PPYEWQVYSSLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACI 899 L + +P + G YV + I G L + G P VA + Sbjct: 69 --------GRLQEPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIV 120 Query: 900 AVEAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKW---KETSSGQ 1070 + S L+ HA G H DVKPEN L+ + +L+D G+AS K T G Sbjct: 121 R-QIGSALDAAHAAGATHRDVKPENILVSA-----DDFAYLVDFGIASATTDEKLTQLGN 174 Query: 1071 HVDYDQRPDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQ 1235 V GT+ Y + + R D+ +L L L G P+QG Q Sbjct: 175 TV----------GTLYYMAPERFSESHATYRADIYALTCVLYECLTGSPPYQGDQ 219
>Q8FUI5:PKN1_COREF Probable serine/threonine protein kinase CE0033 - Corynebacterium| efficiens Length = 660 Score = 51.6 bits (122), Expect = 2e-05 Identities = 36/141 (25%), Positives = 62/141 (43%) Frame = +3 Query: 807 YVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISILEKLHAKGFVHGDVKPENFLLG 986 Y+++ + G L D+ G +PS A I + L+ H G +H DVKP N ++ Sbjct: 87 YIVMERVHGRDLRDIVREDGP-YSPSQAATIMIPVCHALQSSHEAGIIHRDVKPANIMIN 145 Query: 987 QPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFRGTIRYASVHAHLGRTGSRRD 1166 G + ++D G+A +++S + GT +Y S G+ R Sbjct: 146 NTGG-----VKVMDFGIARALDDSTSAM-----TQTAAVIGTAQYLSPEQARGKPADARS 195 Query: 1167 DLESLAYTLIFLLRGRLPWQG 1229 D+ + L L+ GR P++G Sbjct: 196 DVYAAGCVLYELVTGRPPFEG 216
>Q9Z0H0:CDC7_MOUSE Cell division cycle 7-related protein kinase - Mus musculus (Mouse)| Length = 564 Score = 51.6 bits (122), Expect = 2e-05 Identities = 56/200 (28%), Positives = 88/200 (44%), Gaps = 2/200 (1%) Frame = +3 Query: 465 DKVVKMDGVSPEKIGGGEDDASPVPEKVQVGHSPQYKVERKLGKGGFGQVYVGR-RVSGG 641 ++ VK+ G+ + E+ VP+ V V K++ K+G+G F VY+ ++ G Sbjct: 26 EQSVKLSGIKRDF----EELGEAVPQLVNVS-----KIKDKIGEGTFSSVYLATAQLQEG 76 Query: 642 TERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYSSLNGCYGIPWVHYKGRQGDYYVLVM 821 E ++ALK S E Q + G + + Y R+ D+ V+ M Sbjct: 77 HEE------KIALKHLIPTSHPMRIAA--ELQCLTVAGGQDNVMGLKYCFRKNDHVVIAM 128 Query: 822 DILG-PSLWDVWNSLGQTMTPSMVACIAVEAISILEKLHAKGFVHGDVKPENFLLGQPGS 998 L S D+ NSL + + V L+++H G VH DVKP NFL + Sbjct: 129 PYLEHESFLDILNSLSFQEVREYMYNLFVA----LKRIHQFGIVHRDVKPSNFLYNR--- 181 Query: 999 PDEKKLFLIDLGLASKWKET 1058 KK L+D GLA ++T Sbjct: 182 -RLKKYALVDFGLAQGTRDT 200
>P54739:PKAA_STRCO Serine/threonine protein kinase pkaA - Streptomyces coelicolor| Length = 543 Score = 51.2 bits (121), Expect = 2e-05 Identities = 47/146 (32%), Positives = 62/146 (42%), Gaps = 1/146 (0%) Frame = +3 Query: 795 QGDYYVLVMDIL-GPSLWDVWNSLGQTMTPSMVACIAVEAISILEKLHAKGFVHGDVKPE 971 +G+ LVMD++ GP L G +TP A + + L HA G VH D+KP Sbjct: 88 EGELLALVMDLIDGPDLHRYLRENGP-LTPVAAALLTAQIADALAASHADGVVHRDLKPA 146 Query: 972 NFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFRGTIRYASVHAHLGRT 1151 N LL Q G E L D G+A S G R F GT Y + + GR Sbjct: 147 NVLLKQTGG--EMHPMLTDFGIAR--LADSPGL-----TRTHEFVGTPAYVAPESAEGRP 197 Query: 1152 GSRRDDLESLAYTLIFLLRGRLPWQG 1229 + D+ L L+ GR P+ G Sbjct: 198 QTSAVDVYGAGILLYELVTGRPPFGG 223
>Q64595:KGP2_RAT cGMP-dependent protein kinase 2 - Rattus norvegicus (Rat)| Length = 762 Score = 51.2 bits (121), Expect = 2e-05 Identities = 40/141 (28%), Positives = 57/141 (40%) Frame = +3 Query: 807 YVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISILEKLHAKGFVHGDVKPENFLLG 986 Y+L+ LG LW + G P+ C+A + LH G ++ D+KPEN +L Sbjct: 527 YMLLEACLGGELWSILRDRGSFDEPTSKFCVAC-VTEAFDYLHRLGIIYRDLKPENLILD 585 Query: 987 QPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFRGTIRYASVHAHLGRTGSRRD 1166 G L L+D G A K + Q+ F GT Y + L + Sbjct: 586 ADG-----YLKLVDFGFAKK---------IGSGQKTWTFCGTPEYVAPEVILNKGHDFSV 631 Query: 1167 DLESLAYTLIFLLRGRLPWQG 1229 D SL + LL G P+ G Sbjct: 632 DFWSLGILVYELLTGNPPFSG 652
>Q61410:KGP2_MOUSE cGMP-dependent protein kinase 2 - Mus musculus (Mouse)| Length = 762 Score = 51.2 bits (121), Expect = 2e-05 Identities = 40/141 (28%), Positives = 57/141 (40%) Frame = +3 Query: 807 YVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISILEKLHAKGFVHGDVKPENFLLG 986 Y+L+ LG LW + G P+ C+A + LH G ++ D+KPEN +L Sbjct: 527 YMLLEACLGGELWSILRDRGSFDEPTSKFCVAC-VTEAFDYLHLLGIIYRDLKPENLILD 585 Query: 987 QPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFRGTIRYASVHAHLGRTGSRRD 1166 G L L+D G A K + Q+ F GT Y + L + Sbjct: 586 ADG-----YLKLVDFGFAKK---------IGSGQKTWTFCGTPEYVAPEVILNKGHDFSV 631 Query: 1167 DLESLAYTLIFLLRGRLPWQG 1229 D SL + LL G P+ G Sbjct: 632 DFWSLGILVYELLTGNPPFSG 652
>Q13237:KGP2_HUMAN cGMP-dependent protein kinase 2 - Homo sapiens (Human)| Length = 762 Score = 51.2 bits (121), Expect = 2e-05 Identities = 40/141 (28%), Positives = 57/141 (40%) Frame = +3 Query: 807 YVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISILEKLHAKGFVHGDVKPENFLLG 986 Y+L+ LG LW + G P+ C+A + LH G ++ D+KPEN +L Sbjct: 527 YMLLEACLGGELWSILRDRGSFDEPTSKFCVAC-VTEAFDYLHRLGIIYRDLKPENLILD 585 Query: 987 QPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFRGTIRYASVHAHLGRTGSRRD 1166 G L L+D G A K + Q+ F GT Y + L + Sbjct: 586 AEG-----YLKLVDFGFAKK---------IGSGQKTWTFCGTPEYVAPEVILNKGHDFSV 631 Query: 1167 DLESLAYTLIFLLRGRLPWQG 1229 D SL + LL G P+ G Sbjct: 632 DFWSLGILVYELLTGNPPFSG 652
>O15530:PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 - Homo sapiens (Human)| Length = 556 Score = 50.8 bits (120), Expect = 3e-05 Identities = 68/277 (24%), Positives = 113/277 (40%), Gaps = 7/277 (2%) Frame = +3 Query: 480 MDGVSPE-KIGGGEDDASPVPEKVQVGHSPQYKVERKLGKGGFGQVYVGRRVSGGTERTG 656 MDG + E + G G + P + + +K + LG+G F V + R ++ T R Sbjct: 51 MDGTAAEPRPGAGSLQHAQPPPQPRKKRPEDFKFGKILGEGSFSTVVLARELA--TSR-- 106 Query: 657 PDAYEVALKFEHRNSKGCNYGPPY---EWQVYSSLNGCYGIP-WVHYKGRQGDYYVLVMD 824 E A+K + PY E V S L+ + + + ++ + Y+ L Sbjct: 107 ----EYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYA 162 Query: 825 ILGPSLWDVWN--SLGQTMTPSMVACIAVEAISILEKLHAKGFVHGDVKPENFLLGQPGS 998 G L + S +T T A E +S LE LH KG +H D+KPEN LL Sbjct: 163 KNGELLKYIRKIGSFDETCTRFYTA----EIVSALEYLHGKGIIHRDLKPENILLN---- 214 Query: 999 PDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFRGTIRYASVHAHLGRTGSRRDDLES 1178 ++ + + D G A S R + F GT +Y S ++ + DL + Sbjct: 215 -EDMHIQITDFGTAKVLSPESK------QARANSFVGTAQYVSPELLTEKSACKSSDLWA 267 Query: 1179 LAYTLIFLLRGRLPWQGYQGDNKSFLVCKKKMSISPD 1289 L + L+ G P++ +L+ +K + + D Sbjct: 268 LGCIIYQLVAGLPPFRA----GNEYLIFQKIIKLEYD 300
>Q90ZY4:SBK1_DANRE Serine/threonine-protein kinase SBK1 - Danio rerio (Zebrafish)| (Brachydanio rerio) Length = 385 Score = 50.4 bits (119), Expect = 4e-05 Identities = 68/243 (27%), Positives = 109/243 (44%), Gaps = 14/243 (5%) Frame = +3 Query: 540 EKVQVGHSPQYKVERKLGKGGFGQV-YVGRRVSGGTERTGPDAYEVALKF-EHRNSKGCN 713 EK++V + Y+V R+LGKG +G+V V ++ G ++ALKF + +++K + Sbjct: 24 EKLEV--NKYYEVIRELGKGTYGKVDLVIHKIRGS---------KMALKFLKKKSTKLKS 72 Query: 714 YGPPYEWQVYSS----LNGCYGIPWVHYKGRQGDYYVLVMDILGPS--LWDVWNSLGQTM 875 + Y +Y S + +GI + +YYV + PS L+D+ Q Sbjct: 73 FLREYSISLYLSPCPFIINMFGIAF-----ETDEYYVFAQEY-APSGDLFDIIPP--QVG 124 Query: 876 TPSMVACIAVEAISI-LEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWK 1052 P VA V ++I LE LH+K VH D+KPEN L+ + +K+ L D G+ + Sbjct: 125 LPEPVAKRCVHQVAIALEYLHSKKLVHRDIKPENILI---FDKECRKVKLSDFGMTRR-- 179 Query: 1053 ETSSGQHVDYDQRPDIFRGTIRYAS-----VHAHLGRTGSRRDDLESLAYTLIFLLRGRL 1217 +G V GTI Y + H G D+ + L +L G Sbjct: 180 ---AGSPVKR------VSGTIPYTAPELCDTSKHDGFCVDYSTDVWAFGVLLFCMLTGNF 230 Query: 1218 PWQ 1226 PW+ Sbjct: 231 PWE 233
>P72001:PKNE_MYCTU Serine/threonine-protein kinase pknE - Mycobacterium tuberculosis| Length = 566 Score = 50.1 bits (118), Expect = 5e-05 Identities = 64/231 (27%), Positives = 91/231 (39%), Gaps = 9/231 (3%) Frame = +3 Query: 570 YKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPY------E 731 Y++ R +G+GG G VY ER VALK S+ + P + E Sbjct: 16 YRLRRLVGRGGMGDVYEAEDTV--RERI------VALKLM---SETLSSDPVFRTRMQRE 64 Query: 732 WQVYSSLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEA 911 + L + +P + G YV + I G L + G P VA + + Sbjct: 65 ARTAGRLQEPHVVPIHDFGEIDGQLYVDMRLINGVDLAAMLRRQGPLAPPRAVAIVR-QI 123 Query: 912 ISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKW---KETSSGQHVDY 1082 S L+ HA G H DVKPEN L+ + +L+D G+AS K T G V Sbjct: 124 GSALDAAHAAGATHRDVKPENILVSA-----DDFAYLVDFGIASATTDEKLTQLGNTV-- 176 Query: 1083 DQRPDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQ 1235 GT+ Y + + R D+ +L L L G P+QG Q Sbjct: 177 --------GTLYYMAPERFSESHATYRADIYALTCVLYECLTGSPPYQGDQ 219
>Q62070:PIM2_MOUSE Serine/threonine-protein kinase Pim-2 - Mus musculus (Mouse)| Length = 370 Score = 50.1 bits (118), Expect = 5e-05 Identities = 49/179 (27%), Positives = 76/179 (42%), Gaps = 14/179 (7%) Frame = +3 Query: 489 VSPEKIGGGEDDASPVPEKVQVGHSPQYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAY 668 V+P + GG+D A+ +Y++ LGKGGFG V+ G RV+ D Sbjct: 73 VTPTQPPGGKDRAA---------FEAEYRLGPLLGKGGFGTVFAGHRVT--------DRR 115 Query: 669 EVALKFEHRN----------SKGCNYGPPYEWQVYSSLNGCYGI----PWVHYKGRQGDY 806 +VA+K RN S C W+V NG G+ W ++ +G Sbjct: 116 QVAIKVISRNRVLGWSTVSDSVTCPLEVALLWKVGEG-NGHPGVIRLLDW--FETPEGFM 172 Query: 807 YVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISILEKLHAKGFVHGDVKPENFLL 983 VL + L+D G + S + ++ ++ HA+G VH D+K EN L+ Sbjct: 173 LVLERPMPAQDLFDYITEKG-PLGESCSRSFFTQVVAAVQHCHARGVVHRDIKDENILI 230
>Q9UBS0:KS6B2_HUMAN Ribosomal protein S6 kinase beta-2 - Homo sapiens (Human)| Length = 482 Score = 50.1 bits (118), Expect = 5e-05 Identities = 59/243 (24%), Positives = 105/243 (43%), Gaps = 2/243 (0%) Frame = +3 Query: 570 YKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEH-RNSKGCNYGPPYEWQVYS 746 +++ R LGKGG+G+V+ R+V G T A +V K + RN+K + E + Sbjct: 67 FELLRVLGKGGYGKVFQVRKVQG-TNLGKIYAMKVLRKAKIVRNAKDTAHTRA-ERNILE 124 Query: 747 SLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISI-L 923 S+ + + + G Y+++ + G L+ G + + AC + I++ L Sbjct: 125 SVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDT--ACFYLAEITLAL 182 Query: 924 EKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIF 1103 LH++G ++ D+KPEN +L G + L D GL + + H F Sbjct: 183 GHLHSQGIIYRDLKPENIMLSSQG-----HIKLTDFGLCKESIHEGAVTHT--------F 229 Query: 1104 RGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNKSFLVCKKKMSIS 1283 GTI Y + + +R D SL + +L G P+ + + K+++ Sbjct: 230 CGTIEYMAPEILVRSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALP 289 Query: 1284 PDL 1292 P L Sbjct: 290 PYL 292
>P36003:KKR1_YEAST Probable serine/threonine-protein kinase YKL171W - Saccharomyces| cerevisiae (Baker's yeast) Length = 928 Score = 50.1 bits (118), Expect = 5e-05 Identities = 29/102 (28%), Positives = 54/102 (52%), Gaps = 8/102 (7%) Frame = +3 Query: 807 YVLVMDILGPSLWDV---WNSLGQTMTPSMVAC-----IAVEAISILEKLHAKGFVHGDV 962 Y L I +L+D+ W+ ++ P C ++++ +S L+ +H+K VHGD+ Sbjct: 522 YCLTERINDGTLYDLVISWDEFKRSKIPFAERCRLTIFLSLQLLSALKYMHSKTIVHGDI 581 Query: 963 KPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQ 1088 K EN LL + G + K+FL D G++ + E ++ +D+ Sbjct: 582 KLENCLLQKEGKKSDWKVFLCDFGMSCHFDEKHVYRNDTFDE 623
>O94324:PPK31_SCHPO Serine/threonine-protein kinase ppk31 - Schizosaccharomyces pombe| (Fission yeast) Length = 1032 Score = 49.7 bits (117), Expect = 6e-05 Identities = 44/168 (26%), Positives = 71/168 (42%), Gaps = 10/168 (5%) Frame = +3 Query: 582 RKLGKGGFGQVYVGRRVSGGT-------ERTGPDAYEV--ALKFEHRNSKGCNYGPPYEW 734 +++ +G +G+VY+ ++ S G ++ D+ + L E RN YGP Sbjct: 532 KEINRGAYGRVYLAKKRSSGKYFALKMIPKSSLDSLKKIKGLLLEKRNMHIQRYGP---- 587 Query: 735 QVYSSLNGCYGIPWVHYKGRQGDYYVLVMDIL-GPSLWDVWNSLGQTMTPSMVACIAVEA 911 ++Y GDY LVMD G + LG + V A E Sbjct: 588 ----------NTVKLYYAFDSGDYLCLVMDYFNGGDCETLIQKLGP-LPEQWVCQYAAEL 636 Query: 912 ISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKE 1055 ++ +E LH G +H D+KP N L+ + G + L D GL+ +E Sbjct: 637 LNAIELLHQDGIIHHDIKPANMLVDETG-----HIRLTDFGLSENVEE 679
>Q9Z0Z0:KGP1B_MOUSE cGMP-dependent protein kinase 1, beta isozyme - Mus musculus (Mouse)| Length = 686 Score = 49.7 bits (117), Expect = 6e-05 Identities = 42/144 (29%), Positives = 62/144 (43%), Gaps = 3/144 (2%) Frame = +3 Query: 807 YVLVMDILGPSLWDVWNSLGQ---TMTPSMVACIAVEAISILEKLHAKGFVHGDVKPENF 977 Y+L+ LG LW + G + T AC+ VEA + L H+KG ++ D+KPEN Sbjct: 450 YMLMEACLGGELWTILRDRGSFEDSTTRFYTACV-VEAFAYL---HSKGIIYRDLKPENL 505 Query: 978 LLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFRGTIRYASVHAHLGRTGS 1157 +L G L+D G A K + + ++ F GT Y + L + Sbjct: 506 ILDHRGYAK-----LVDFGFAKK---------IGFGKKTWTFCGTPEYVAPEIILNKGHD 551 Query: 1158 RRDDLESLAYTLIFLLRGRLPWQG 1229 D SL + LL G P+ G Sbjct: 552 ISADYWSLGILMYELLTGSPPFSG 575
>P14619:KGP1B_HUMAN cGMP-dependent protein kinase 1, beta isozyme - Homo sapiens (Human)| Length = 686 Score = 49.7 bits (117), Expect = 6e-05 Identities = 42/144 (29%), Positives = 62/144 (43%), Gaps = 3/144 (2%) Frame = +3 Query: 807 YVLVMDILGPSLWDVWNSLGQ---TMTPSMVACIAVEAISILEKLHAKGFVHGDVKPENF 977 Y+L+ LG LW + G + T AC+ VEA + L H+KG ++ D+KPEN Sbjct: 450 YMLMEACLGGELWTILRDRGSFEDSTTRFYTACV-VEAFAYL---HSKGIIYRDLKPENL 505 Query: 978 LLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFRGTIRYASVHAHLGRTGS 1157 +L G L+D G A K + + ++ F GT Y + L + Sbjct: 506 ILDHRGYAK-----LVDFGFAKK---------IGFGKKTWTFCGTPEYVAPEIILNKGHD 551 Query: 1158 RRDDLESLAYTLIFLLRGRLPWQG 1229 D SL + LL G P+ G Sbjct: 552 ISADYWSLGILMYELLTGSPPFSG 575
>P21136:KGP1B_BOVIN cGMP-dependent protein kinase 1, beta isozyme - Bos taurus (Bovine)| Length = 686 Score = 49.7 bits (117), Expect = 6e-05 Identities = 42/144 (29%), Positives = 62/144 (43%), Gaps = 3/144 (2%) Frame = +3 Query: 807 YVLVMDILGPSLWDVWNSLGQ---TMTPSMVACIAVEAISILEKLHAKGFVHGDVKPENF 977 Y+L+ LG LW + G + T AC+ VEA + L H+KG ++ D+KPEN Sbjct: 450 YMLMEACLGGELWTILRDRGSFEDSTTRFYTACV-VEAFAYL---HSKGIIYRDLKPENL 505 Query: 978 LLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFRGTIRYASVHAHLGRTGS 1157 +L G L+D G A K + + ++ F GT Y + L + Sbjct: 506 ILDHRGYAK-----LVDFGFAKK---------IGFGKKTWTFCGTPEYVAPEIILNKGHD 551 Query: 1158 RRDDLESLAYTLIFLLRGRLPWQG 1229 D SL + LL G P+ G Sbjct: 552 ISADYWSLGILMYELLTGSPPFSG 575
>O77676:KGP1A_RABIT cGMP-dependent protein kinase 1, alpha isozyme - Oryctolagus| cuniculus (Rabbit) Length = 671 Score = 49.7 bits (117), Expect = 6e-05 Identities = 42/144 (29%), Positives = 62/144 (43%), Gaps = 3/144 (2%) Frame = +3 Query: 807 YVLVMDILGPSLWDVWNSLGQ---TMTPSMVACIAVEAISILEKLHAKGFVHGDVKPENF 977 Y+L+ LG LW + G + T AC+ VEA + L H+KG ++ D+KPEN Sbjct: 435 YMLMEACLGGELWTILRDRGSFEDSTTRFYTACV-VEAFAYL---HSKGIIYRDLKPENL 490 Query: 978 LLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFRGTIRYASVHAHLGRTGS 1157 +L G L+D G A K + + ++ F GT Y + L + Sbjct: 491 ILDHRGYAK-----LVDFGFAKK---------IGFGKKTWTFCGTPEYVAPEIILNKGHD 536 Query: 1158 RRDDLESLAYTLIFLLRGRLPWQG 1229 D SL + LL G P+ G Sbjct: 537 ISADYWSLGILMYELLTGSPPFSG 560
>Q13976:KGP1A_HUMAN cGMP-dependent protein kinase 1, alpha isozyme - Homo sapiens (Human)| Length = 671 Score = 49.7 bits (117), Expect = 6e-05 Identities = 42/144 (29%), Positives = 62/144 (43%), Gaps = 3/144 (2%) Frame = +3 Query: 807 YVLVMDILGPSLWDVWNSLGQ---TMTPSMVACIAVEAISILEKLHAKGFVHGDVKPENF 977 Y+L+ LG LW + G + T AC+ VEA + L H+KG ++ D+KPEN Sbjct: 435 YMLMEACLGGELWTILRDRGSFEDSTTRFYTACV-VEAFAYL---HSKGIIYRDLKPENL 490 Query: 978 LLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFRGTIRYASVHAHLGRTGS 1157 +L G L+D G A K + + ++ F GT Y + L + Sbjct: 491 ILDHRGYAK-----LVDFGFAKK---------IGFGKKTWTFCGTPEYVAPEIILNKGHD 536 Query: 1158 RRDDLESLAYTLIFLLRGRLPWQG 1229 D SL + LL G P+ G Sbjct: 537 ISADYWSLGILMYELLTGSPPFSG 560
>P00516:KGP1A_BOVIN cGMP-dependent protein kinase 1, alpha isozyme - Bos taurus (Bovine)| Length = 671 Score = 49.7 bits (117), Expect = 6e-05 Identities = 42/144 (29%), Positives = 62/144 (43%), Gaps = 3/144 (2%) Frame = +3 Query: 807 YVLVMDILGPSLWDVWNSLGQ---TMTPSMVACIAVEAISILEKLHAKGFVHGDVKPENF 977 Y+L+ LG LW + G + T AC+ VEA + L H+KG ++ D+KPEN Sbjct: 435 YMLMEACLGGELWTILRDRGSFEDSTTRFYTACV-VEAFAYL---HSKGIIYRDLKPENL 490 Query: 978 LLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFRGTIRYASVHAHLGRTGS 1157 +L G L+D G A K + + ++ F GT Y + L + Sbjct: 491 ILDHRGYAK-----LVDFGFAKK---------IGFGKKTWTFCGTPEYVAPEIILNKGHD 536 Query: 1158 RRDDLESLAYTLIFLLRGRLPWQG 1229 D SL + LL G P+ G Sbjct: 537 ISADYWSLGILMYELLTGSPPFSG 560
>P73469:SPKF_SYNY3 Serine/threonine-protein kinase F - Synechocystis sp. (strain PCC| 6803) Length = 495 Score = 49.3 bits (116), Expect = 8e-05 Identities = 35/142 (24%), Positives = 64/142 (45%) Frame = +3 Query: 789 GRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISILEKLHAKGFVHGDVKP 968 G+Q ++ LV + + + ++ + V + E + IL +H G +H D+KP Sbjct: 131 GKQDQFFYLVQEFINGQDLEKTVEKHGPLSEAEVRWVLTEMLKILSFVHGTGAIHRDIKP 190 Query: 969 ENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFRGTIRYASVHAHLGR 1148 N + Q G KL+L+D G K+ ++G + I+ ++ +A G Sbjct: 191 SNLMRDQEG-----KLYLLDFGAV---KQATAGVGASNEGSTGIY--SMGFAPPEQMAGN 240 Query: 1149 TGSRRDDLESLAYTLIFLLRGR 1214 DL +LA T ++LL G+ Sbjct: 241 QVYPATDLYALAVTCLYLLTGK 262
>Q753D9:PKH3_ASHGO Serine/threonine-protein kinase PKH3 - Ashbya gossypii (Yeast)| (Eremothecium gossypii) Length = 726 Score = 48.9 bits (115), Expect = 1e-04 Identities = 34/116 (29%), Positives = 56/116 (48%) Frame = +3 Query: 906 EAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYD 1085 + + +E +H+ G +H D+KPEN LL + G +L + D G A ++ +G D D Sbjct: 119 QLVDTVEYIHSMGVIHRDLKPENVLLDKEG-----RLMIADFGAAYTVGQSDAGS--DGD 171 Query: 1086 QRPDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNKSF 1253 + F GT Y S L D+ +L L L+G P++G Q + ++F Sbjct: 172 KPATSFVGTAEYVSPELLLENKSYYSSDVWALGCMLYQFLQGTPPFRG-QNEMETF 226
>P70236:MP2K6_MOUSE Dual specificity mitogen-activated protein kinase kinase 6 - Mus| musculus (Mouse) Length = 334 Score = 48.9 bits (115), Expect = 1e-04 Identities = 54/204 (26%), Positives = 91/204 (44%), Gaps = 6/204 (2%) Frame = +3 Query: 792 RQGDYYVLVMDILGPSLWDVWNSL---GQTMTPSMVACIAVEAISILEKLHAK-GFVHGD 959 R+GD ++ M+++ SL + + GQT+ ++ IAV + LE LH+K +H D Sbjct: 121 REGDVWIC-MELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRD 179 Query: 960 VKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFRGTIRYASVHAH 1139 VKP N L+ G ++ + D G+ S + S + +D +P + ++ Sbjct: 180 VKPSNVLINTLG-----QVKMCDFGI-SGYLVDSVAKTIDAGCKP-----YMAPERINPE 228 Query: 1140 LGRTG-SRRDDLESLAYTLIFLLRGRLPWQGYQGDNKSFLVCKKKM-SISPDLMCCYCAP 1313 L + G S + D+ SL T+I L R P+ + F K+ + SP L + Sbjct: 229 LNQKGYSVKSDIWSLGITMIELAILRFPYDSW---GTPFQQLKQVVEEPSPQLPADKFSA 285 Query: 1314 PFKLFLETVTNMKFDEEPNYPKLI 1385 F F E P YP+L+ Sbjct: 286 DFVDFTSQCLKKNSKERPTYPELM 309
>P52564:MP2K6_HUMAN Dual specificity mitogen-activated protein kinase kinase 6 - Homo| sapiens (Human) Length = 334 Score = 48.9 bits (115), Expect = 1e-04 Identities = 54/204 (26%), Positives = 91/204 (44%), Gaps = 6/204 (2%) Frame = +3 Query: 792 RQGDYYVLVMDILGPSLWDVWNSL---GQTMTPSMVACIAVEAISILEKLHAK-GFVHGD 959 R+GD ++ M+++ SL + + GQT+ ++ IAV + LE LH+K +H D Sbjct: 121 REGDVWIC-MELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRD 179 Query: 960 VKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFRGTIRYASVHAH 1139 VKP N L+ G ++ + D G+ S + S + +D +P + ++ Sbjct: 180 VKPSNVLINALG-----QVKMCDFGI-SGYLVDSVAKTIDAGCKP-----YMAPERINPE 228 Query: 1140 LGRTG-SRRDDLESLAYTLIFLLRGRLPWQGYQGDNKSFLVCKKKM-SISPDLMCCYCAP 1313 L + G S + D+ SL T+I L R P+ + F K+ + SP L + Sbjct: 229 LNQKGYSVKSDIWSLGITMIELAILRFPYDSW---GTPFQQLKQVVEEPSPQLPADKFSA 285 Query: 1314 PFKLFLETVTNMKFDEEPNYPKLI 1385 F F E P YP+L+ Sbjct: 286 EFVDFTSQCLKKNSKERPTYPELM 309
>Q5E9X2:MP2K6_BOVIN Dual specificity mitogen-activated protein kinase kinase 6 - Bos| taurus (Bovine) Length = 334 Score = 48.9 bits (115), Expect = 1e-04 Identities = 54/204 (26%), Positives = 91/204 (44%), Gaps = 6/204 (2%) Frame = +3 Query: 792 RQGDYYVLVMDILGPSLWDVWNSL---GQTMTPSMVACIAVEAISILEKLHAK-GFVHGD 959 R+GD ++ M+++ SL + + GQT+ ++ IAV + LE LH+K +H D Sbjct: 121 REGDVWIC-MELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRD 179 Query: 960 VKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFRGTIRYASVHAH 1139 VKP N L+ G ++ + D G+ S + S + +D +P + ++ Sbjct: 180 VKPSNVLINALG-----QVKMCDFGI-SGYLVDSVAKTIDAGCKP-----YMAPERINPE 228 Query: 1140 LGRTG-SRRDDLESLAYTLIFLLRGRLPWQGYQGDNKSFLVCKKKM-SISPDLMCCYCAP 1313 L + G S + D+ SL T+I L R P+ + F K+ + SP L + Sbjct: 229 LNQKGYSVKSDIWSLGITMIELAILRFPYDSW---GTPFQQLKQVVEEPSPQLPADKFSE 285 Query: 1314 PFKLFLETVTNMKFDEEPNYPKLI 1385 F F E P YP+L+ Sbjct: 286 EFVDFTSQCLKKNSKERPTYPELM 309
>Q09639:GRK2_CAEEL G protein-coupled receptor kinase 2 - Caenorhabditis elegans| Length = 707 Score = 48.9 bits (115), Expect = 1e-04 Identities = 60/244 (24%), Positives = 101/244 (41%), Gaps = 3/244 (1%) Frame = +3 Query: 570 YKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYSS 749 + V R +G+GGFG+VY R+ G + +K + + N + S+ Sbjct: 191 FSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALN--ERIMLSLVST 248 Query: 750 LNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISILEK 929 C I + Y + D ++D++ S T + A E I LE Sbjct: 249 GQDCPFIVCMTYAFQSPDKLCFILDLMNGGDLHYHLSQHGVFTEQEMIFYASEVILGLEH 308 Query: 930 LHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLA---SKWKETSSGQHVDYDQRPDI 1100 +H + V+ D+KP N LL + G + + DLGLA SK K +S Y P++ Sbjct: 309 MHNRFVVYRDLKPANILLDENG-----HVRVSDLGLACDYSKKKPHASVGTHGY-MAPEV 362 Query: 1101 FRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNKSFLVCKKKMSI 1280 + Y S D SL L LL+G P++ ++ +K+ + KM++ Sbjct: 363 LAKGVAYDS-----------SADWFSLGCMLYKLLKGHSPFRQHKSKDKNEI---DKMTL 408 Query: 1281 SPDL 1292 + D+ Sbjct: 409 TQDI 412
>Q7RJG2:CDPK4_PLAYO Calcium-dependent protein kinase 4 - Plasmodium yoelii yoelii| Length = 528 Score = 48.9 bits (115), Expect = 1e-04 Identities = 58/222 (26%), Positives = 95/222 (42%), Gaps = 1/222 (0%) Frame = +3 Query: 567 QYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYS 746 QYK + LGKG FG+V + + + TG + + +H K E ++ Sbjct: 69 QYKGIKILGKGSFGEVILSK-----DKHTGHEYAIKVISKKHVKRKTDKQSLLREVELLK 123 Query: 747 SLNGCYGIPWVHYKGRQGDYYVLVMDIL-GPSLWDVWNSLGQTMTPSMVACIAVEAISIL 923 L+ I ++ +YY LV D+ G L+D S + A I + +S + Sbjct: 124 MLDHI-NIMKLYEFFEDNNYYYLVSDVYSGGELFDEIISRKRFYEVD-AARIIKQVLSGI 181 Query: 924 EKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIF 1103 +H VH D+KPEN LL + + ++ + +ID GL++ H +Y ++ Sbjct: 182 TYMHKNNVVHRDLKPENILL-ETKNKEDMIIKIIDFGLST---------HFEYSKKMKDK 231 Query: 1104 RGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQG 1229 GT Y + L T + D+ S L LL G P+ G Sbjct: 232 IGTAYYIAPDV-LHGTYDEKCDIWSCGVILYILLSGCPPFNG 272
>Q8IBS5:CDPK4_PLAF7 Calcium-dependent protein kinase 4 - Plasmodium falciparum (isolate| 3D7) Length = 528 Score = 48.9 bits (115), Expect = 1e-04 Identities = 59/222 (26%), Positives = 95/222 (42%), Gaps = 1/222 (0%) Frame = +3 Query: 567 QYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYS 746 QYK + LGKG FG+V + R + TG + + +H K E ++ Sbjct: 69 QYKGIKILGKGSFGEVILSR-----DKHTGHEYAIKVISKKHVKRKTDKESLLREVELLK 123 Query: 747 SLNGCYGIPWVHYKGRQGDYYVLVMDIL-GPSLWDVWNSLGQTMTPSMVACIAVEAISIL 923 L+ I ++ +YY LV D+ G L+D S + A I + +S + Sbjct: 124 MLDHI-NIMKLYEFFEDNNYYYLVSDVYTGGELFDEIISRKRFYEID-AARIIKQILSGI 181 Query: 924 EKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIF 1103 +H VH D+KPEN LL + + ++ + +ID GL++ H +Y ++ Sbjct: 182 TYMHKNNVVHRDLKPENILL-ETKNKEDMIIKIIDFGLST---------HFEYSKKMKDK 231 Query: 1104 RGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQG 1229 GT Y + L T + D+ S L LL G P+ G Sbjct: 232 IGTAYYIAPDV-LHGTYDEKCDIWSCGVILYILLSGCPPFNG 272
>P62345:CDPK4_PLABA Calcium-dependent protein kinase 4 - Plasmodium berghei (strain Anka)| Length = 528 Score = 48.9 bits (115), Expect = 1e-04 Identities = 58/222 (26%), Positives = 95/222 (42%), Gaps = 1/222 (0%) Frame = +3 Query: 567 QYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYS 746 QYK + LGKG FG+V + + + TG + + +H K E ++ Sbjct: 69 QYKGIKILGKGSFGEVILSK-----DKHTGHEYAIKVISKKHVKRKTDKQSLLREVELLK 123 Query: 747 SLNGCYGIPWVHYKGRQGDYYVLVMDIL-GPSLWDVWNSLGQTMTPSMVACIAVEAISIL 923 L+ I ++ +YY LV D+ G L+D S + A I + +S + Sbjct: 124 MLDHI-NIMKLYEFFEDNNYYYLVSDVYSGGELFDEIISRKRFYEVD-AARIIKQVLSGI 181 Query: 924 EKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIF 1103 +H VH D+KPEN LL + + ++ + +ID GL++ H +Y ++ Sbjct: 182 TYMHKNNVVHRDLKPENILL-ETKNKEDMIIKIIDFGLST---------HFEYSKKMKDK 231 Query: 1104 RGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQG 1229 GT Y + L T + D+ S L LL G P+ G Sbjct: 232 IGTAYYIAPDV-LHGTYDEKCDIWSCGVILYILLSGCPPFNG 272
>Q9ESG9:PMYT1_MOUSE Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory| kinase - Mus musculus (Mouse) Length = 490 Score = 48.5 bits (114), Expect = 1e-04 Identities = 36/122 (29%), Positives = 58/122 (47%), Gaps = 3/122 (2%) Frame = +3 Query: 795 QGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISILEKLHAKGFVHGDVKPEN 974 +G L ++ GPSL + G ++ + V + + L+ LH++G VH DVKP N Sbjct: 170 EGGILYLQTELCGPSLQQHCEAWGASLPEAQVWGYLRDILLALDHLHSQGLVHLDVKPAN 229 Query: 975 FLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQR---PDIFRGTIRYASVHAHLG 1145 LG G + L D GL + T +G+ + D R P++ +G+ A+ LG Sbjct: 230 IFLGPRG-----RCKLGDFGLLVELGSTGAGEAQEGDPRYMAPELLQGSYGTAADVFSLG 284 Query: 1146 RT 1151 T Sbjct: 285 LT 286
>Q5RJI5:BRSK1_MOUSE BR serine/threonine-protein kinase 1 - Mus musculus (Mouse)| Length = 778 Score = 48.5 bits (114), Expect = 1e-04 Identities = 75/278 (26%), Positives = 111/278 (39%), Gaps = 15/278 (5%) Frame = +3 Query: 492 SPEKIGGGEDDASPVPEKVQVGHSPQ-------YKVERKLGKGGFGQVYVGRRVSGGTER 650 S K GGG A +P H PQ Y++E+ LGKG G V +G G + Sbjct: 3 SGSKEGGGGSPAYHLPHPHP--HPPQHAQYVGPYRLEKTLGKGQTGLVKLGVHCITGQK- 59 Query: 651 TGPDAYEVALKFEHRNSKGCNYGPPYEWQV-YSSLNGCYGIPWVHYKGRQGDYYVLVMD- 824 VA+K +R + E ++ L + +H Y LV++ Sbjct: 60 -------VAVKIVNREKLSESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEH 112 Query: 825 ILGPSLWDVWNSLGQTMTPSMVACIAVEAISILEKLHAKGFVHGDVKPENFLLGQPGSPD 1004 + G L+D G+ +TP + +S L+ H+ H D+KPEN LL D Sbjct: 113 VSGGELFDYLVKKGR-LTPKEARKFFRQIVSALDFCHSYSICHRDLKPENLLL------D 165 Query: 1005 EK-KLFLIDLGLAS-----KWKETSSGQHVDYDQRPDIFRGTIRYASVHAHLGRTGSRRD 1166 EK + + D G+AS ETS G + P++ +G + RR Sbjct: 166 EKNNIRIADFGMASLQVGDSLLETSCGS--PHYACPEVIKGE-----------KYDGRRA 212 Query: 1167 DLESLAYTLIFLLRGRLPWQGYQGDNKSFLVCKKKMSI 1280 D+ S L LL G LP + DN L+ K K + Sbjct: 213 DMWSCGVILFALLVGALP---FDDDNLRQLLEKVKRGV 247
>Q60806:PLK3_MOUSE Serine/threonine-protein kinase PLK3 - Mus musculus (Mouse)| Length = 631 Score = 48.1 bits (113), Expect = 2e-04 Identities = 55/235 (23%), Positives = 93/235 (39%) Frame = +3 Query: 570 YKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYSS 749 Y R LGKGGF + Y G + + H+ K N E +++ Sbjct: 63 YTKGRLLGKGGFARCYEATDTESGIAYAVKVIPQSRVAKPHQREKILN-----EIELHRD 117 Query: 750 LNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISILEK 929 L + + + H+ + Y+ + SL +W + + P V + +S L+ Sbjct: 118 LQHRHIVRFSHHFEDADNIYIFLELCSRKSLAHIWKARHTLLEPE-VRYYLRQILSGLKY 176 Query: 930 LHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFRG 1109 LH +G +H D+K NF + D +L + D GLA++ + +QR G Sbjct: 177 LHQRGILHRDLKLGNFFI-----TDNMELKVGDFGLAARLEPP--------EQRKKTICG 223 Query: 1110 TIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNKSFLVCKKKM 1274 T Y + L + D+ SL + LL G P++ D K C K++ Sbjct: 224 TPNYVAPEVLLRQGHGPEADVWSLGCVMYTLLCGSPPFE--TADLKETYRCIKQV 276
>Q8NU98:PKN1_CORGL Probable serine/threonine protein kinase pknB - Corynebacterium| glutamicum (Brevibacterium flavum) Length = 646 Score = 48.1 bits (113), Expect = 2e-04 Identities = 51/229 (22%), Positives = 93/229 (40%), Gaps = 8/229 (3%) Frame = +3 Query: 567 QYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRN-SKGCNYGPPYEWQV- 740 +Y+++ +G GG +V+ G E VA+K + +K N+ + + Sbjct: 8 RYELDAVIGSGGMSEVFAATDTLIGRE--------VAVKMLRIDLAKDPNFRERFRREAQ 59 Query: 741 ------YSSLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIA 902 +SS+ + V G Y V+ + G +L +V G TP A I Sbjct: 60 NSGRLSHSSIVAVFDTGEVDKDGTSVPYIVMER-VQGRNLREVVTEDG-VFTPVEAANIL 117 Query: 903 VEAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDY 1082 + L+ H G +H DVKP N ++ G + ++D G+A +++S Sbjct: 118 IPVCEALQASHDAGIIHRDVKPANIMITNTGG-----VKVMDFGIARAVNDSTSAM---- 168 Query: 1083 DQRPDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQG 1229 + GT +Y S G+ R D+ + + L+ G+ P++G Sbjct: 169 -TQTSAVIGTAQYLSPEQARGKPADARSDIYATGCVMYELVTGKPPFEG 216
>Q9KIG4:PK1_STRTO Serine/threonine-protein kinase PK-1 - Streptomyces toyocaensis| Length = 641 Score = 48.1 bits (113), Expect = 2e-04 Identities = 58/236 (24%), Positives = 97/236 (41%), Gaps = 3/236 (1%) Frame = +3 Query: 567 QYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRN-SKGCNYGPPYEWQVY 743 +Y+V+ ++ GG VY R V +R +ALK H + + ++ + + Sbjct: 17 RYRVDARIAVGGMATVY--RAVDTRLDRV------LALKVMHPSLAADASFVERFIREAK 68 Query: 744 SSLNGCY-GIPWVHYKGRQGDYYVLVMD-ILGPSLWDVWNSLGQTMTPSMVACIAVEAIS 917 S + + V +G G Y L M+ I G +L DV G + P I ++ Sbjct: 69 SVARLAHPNVVQVFDQGTDGAYVYLAMEYIAGCTLRDVLRERG-ALQPRAALDILEPVLA 127 Query: 918 ILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPD 1097 L H GFVH D+KPEN L+G D+ ++ + D GL ++ Sbjct: 128 ALGAAHRAGFVHRDMKPENVLIG-----DDGRVKVADFGLVRAVDSVTN--------TTG 174 Query: 1098 IFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNKSFLVCK 1265 GT+ Y + T R D+ + L +L G P + GD+ + ++ K Sbjct: 175 TVLGTVSYLAPEQIEHGTADPRVDVYACGILLYEMLTGEKP---HDGDSPAIVLYK 227
>O55173:PDPK1_RAT 3-phosphoinositide-dependent protein kinase 1 - Rattus norvegicus| (Rat) Length = 559 Score = 48.1 bits (113), Expect = 2e-04 Identities = 35/128 (27%), Positives = 57/128 (44%) Frame = +3 Query: 906 EAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYD 1085 E +S LE LH KG +H D+KPEN LL ++ + + D G A S Sbjct: 191 EIVSALEYLHGKGIIHRDLKPENILLN-----EDMHIQITDFGTAKVLSPDSK------Q 239 Query: 1086 QRPDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNKSFLVCK 1265 R + F GT +Y S ++ + DL +L + L+ G P++ +L+ + Sbjct: 240 ARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRA----GNEYLIFQ 295 Query: 1266 KKMSISPD 1289 K + + D Sbjct: 296 KIIKLEYD 303
>Q7TT49:MRCKB_RAT Serine/threonine-protein kinase MRCK beta - Rattus norvegicus (Rat)| Length = 1713 Score = 48.1 bits (113), Expect = 2e-04 Identities = 57/226 (25%), Positives = 95/226 (42%), Gaps = 4/226 (1%) Frame = +3 Query: 558 HSPQYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFE--HRNSKGCNYGPPYE 731 H +++ + +G+G FG+V V + + TER A ++ K+E R C + Sbjct: 72 HREDFEIIKVIGRGAFGEVAVVKMKN--TERIY--AMKILNKWEMLKRAETAC-----FR 122 Query: 732 WQVYSSLNG-CYGIPWVHYKGRQGDYYVLVMDI-LGPSLWDVWNSLGQTMTPSMVACIAV 905 + +NG C I +HY + +Y LVMD +G L + + + M Sbjct: 123 EERDVLVNGDCQWITALHYAFQDENYLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYIG 182 Query: 906 EAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYD 1085 E + ++ +H +VH D+KP+N LL G + L D G K + + Q Sbjct: 183 EMVLAIDSIHQLHYVHRDIKPDNVLLDVNG-----HIRLADFGSCLKMNDDGTVQSSVAV 237 Query: 1086 QRPDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPW 1223 PD I A + +G+ G D SL + +L G P+ Sbjct: 238 GTPDYISPEILQA-MEDGMGKYGP-ECDWWSLGVCMYEMLYGETPF 281
>P32023:KGP25_DROME cGMP-dependent protein kinase, isozyme 2 forms cD5/T2 - Drosophila| melanogaster (Fruit fly) Length = 934 Score = 48.1 bits (113), Expect = 2e-04 Identities = 39/144 (27%), Positives = 60/144 (41%), Gaps = 3/144 (2%) Frame = +3 Query: 807 YVLVMDILGPSLWDVWNSLGQ---TMTPSMVACIAVEAISILEKLHAKGFVHGDVKPENF 977 Y+L+ LG LW + G + T AC+ + + LH++ ++ D+KPEN Sbjct: 698 YMLMESCLGGELWTILRDKGNFDDSTTRFYTACV----VEAFDYLHSRNIIYRDLKPENL 753 Query: 978 LLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFRGTIRYASVHAHLGRTGS 1157 LL + G + L+D G A K + ++ F GT Y + L R Sbjct: 754 LLNERG-----YVKLVDFGFAKK---------LQTGRKTWTFCGTPEYVAPEVILNRGHD 799 Query: 1158 RRDDLESLAYTLIFLLRGRLPWQG 1229 D SL + LL G P+ G Sbjct: 800 ISADYWSLGVLMFELLTGTPPFTG 823
>Q03043:KGP24_DROME cGMP-dependent protein kinase, isozyme 2 forms cD4/T1/T3A/T3B -| Drosophila melanogaster (Fruit fly) Length = 1088 Score = 48.1 bits (113), Expect = 2e-04 Identities = 39/144 (27%), Positives = 60/144 (41%), Gaps = 3/144 (2%) Frame = +3 Query: 807 YVLVMDILGPSLWDVWNSLGQ---TMTPSMVACIAVEAISILEKLHAKGFVHGDVKPENF 977 Y+L+ LG LW + G + T AC+ + + LH++ ++ D+KPEN Sbjct: 852 YMLMESCLGGELWTILRDKGNFDDSTTRFYTACV----VEAFDYLHSRNIIYRDLKPENL 907 Query: 978 LLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFRGTIRYASVHAHLGRTGS 1157 LL + G + L+D G A K + ++ F GT Y + L R Sbjct: 908 LLNERG-----YVKLVDFGFAKK---------LQTGRKTWTFCGTPEYVAPEVILNRGHD 953 Query: 1158 RRDDLESLAYTLIFLLRGRLPWQG 1229 D SL + LL G P+ G Sbjct: 954 ISADYWSLGVLMFELLTGTPPFTG 977
>Q8TDC3:BRSK1_HUMAN BR serine/threonine-protein kinase 1 - Homo sapiens (Human)| Length = 794 Score = 48.1 bits (113), Expect = 2e-04 Identities = 69/283 (24%), Positives = 110/283 (38%), Gaps = 8/283 (2%) Frame = +3 Query: 456 EFADKVVKMDGVSPEKIGGGEDDASPVPEKVQVGHSPQYKVERKLGKGGFGQVYVGRRVS 635 E D V + E GGG ++ + Y++E+ LGKG G V +G Sbjct: 12 ESPDGDVSVPERKDEVAGGGGEEEEAEERGRHAQYVGPYRLEKTLGKGQTGLVKLGVHCI 71 Query: 636 GGTERTGPDAYEVALKFEHRN--SKGCNYGPPYEWQVYSSLNGCYGIPWVHYKGRQGDYY 809 G +VA+K +R S+ E + + + + + Y Sbjct: 72 TG--------QKVAIKIVNREKLSESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLY 123 Query: 810 VLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISILEKLHAKGFVHGDVKPENFLLGQ 989 +++ + G L+D G+ +TP + +S L+ H+ H D+KPEN LL Sbjct: 124 LVLEHVSGGELFDYLVKKGR-LTPKEARKFFRQIVSALDFCHSYSICHRDLKPENLLL-- 180 Query: 990 PGSPDEK-KLFLIDLGLAS-----KWKETSSGQHVDYDQRPDIFRGTIRYASVHAHLGRT 1151 DEK + + D G+AS ETS G + P++ +G + Sbjct: 181 ----DEKNNIRIADFGMASLQVGDSLLETSCGS--PHYACPEVIKGE-----------KY 223 Query: 1152 GSRRDDLESLAYTLIFLLRGRLPWQGYQGDNKSFLVCKKKMSI 1280 RR D+ S L LL G LP + DN L+ K K + Sbjct: 224 DGRRADMWSCGVILFALLVGALP---FDDDNLRQLLEKVKRGV 263
>O01427:AIR2_CAEEL Aurora/Ipl1-related protein kinase 2 - Caenorhabditis elegans| Length = 305 Score = 48.1 bits (113), Expect = 2e-04 Identities = 63/268 (23%), Positives = 105/268 (39%), Gaps = 3/268 (1%) Frame = +3 Query: 495 PEKIGGGEDDASPVPEKVQVGHSPQYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEV 674 P I E + P+K +++ R LGKG FG VY+ R +G + V Sbjct: 5 PPVINLPEKETVNTPQKGGKFTINDFEIGRPLGKGKFGSVYLARTKTGH--------FHV 56 Query: 675 ALKFEHRN---SKGCNYGPPYEWQVYSSLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLW 845 A+K ++ S G + E ++ S LN I Y Y+++ G ++ Sbjct: 57 AIKVLFKSQLISGGVEHQLEREIEIQSHLNHPNIIKLYTYFWDAKKIYLVLEYAPGGEMY 116 Query: 846 DVWNSLGQTMTPSMVACIAVEAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLI 1025 ++ + + A E L H K +H D+KPEN L+G G +L + Sbjct: 117 KQL-TVSKRFSEPTAAKYMYEIADALSYCHRKNVIHRDIKPENLLIGSQG-----ELKIG 170 Query: 1026 DLGLASKWKETSSGQHVDYDQRPDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLL 1205 D G W H ++R + GT+ Y G S DL ++ L Sbjct: 171 DFG----W-----SVHAPSNKRQTMC-GTMDYLPPEMVNGADHSDAVDLWAIGVLCYEFL 220 Query: 1206 RGRLPWQGYQGDNKSFLVCKKKMSISPD 1289 G+ P++ ++ +K++ K PD Sbjct: 221 VGKPPFE-HEDQSKTYAAIKAARFTYPD 247
>P74745:SPKC_SYNY3 Serine/threonine-protein kinase C - Synechocystis sp. (strain PCC| 6803) Length = 535 Score = 47.8 bits (112), Expect = 2e-04 Identities = 61/236 (25%), Positives = 99/236 (41%), Gaps = 18/236 (7%) Frame = +3 Query: 567 QYKVERKLGKGGFGQVYVGRRVSGGTERT-----------GPDAYEVALKFEHRNSK--- 704 +Y++ LG+GGFG+ ++ + + R P+ + HR + Sbjct: 11 RYRIIETLGRGGFGETFLAQDTHMPSARKCVIKHLKPVLENPEIPSWLRERFHREAATLE 70 Query: 705 --GCNYGPPYEWQVYSSLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMT 878 G N+ P Q+Y+ Y D+Y++ I G +L G + Sbjct: 71 ELGENH--PQIPQLYA------------YFSEGEDFYLVQEWIPGLTLTQAHAQKGN-FS 115 Query: 879 PSMVACIAVEAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKET 1058 + V + + + +LE +H + +H D+KP+N +L + + K LID G+ KET Sbjct: 116 STAVEELLLGILPVLEFIHQRRIIHRDIKPDNIILREA----DGKPILIDFGII---KET 168 Query: 1059 SSGQHVDYDQRP--DIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLP 1220 G V+ D R + GT Y + GR DL SL T IFLL G+ P Sbjct: 169 -MGTLVNPDGRSAYSVALGTPGYMASEQAAGRP-VFSSDLYSLGLTAIFLLTGKTP 222
>Q8TFG6:PPK18_SCHPO Serine/threonine-protein kinase ppk18 - Schizosaccharomyces pombe| (Fission yeast) Length = 1316 Score = 47.8 bits (112), Expect = 2e-04 Identities = 44/170 (25%), Positives = 71/170 (41%), Gaps = 2/170 (1%) Frame = +3 Query: 570 YKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEV-ALKFEHRNSKGCNYGPPYEWQVYS 746 Y++ + + KG FG VY+ R+ + G + Y + L+ SK E V Sbjct: 564 YEIIKPISKGTFGTVYLSRKNTTG------EIYAIKVLRKVDMISKNQVANVKAERAVLM 617 Query: 747 SLNGCYGIPWVHYKGRQGDYYVLVMDIL-GPSLWDVWNSLGQTMTPSMVACIAVEAISIL 923 + + ++Y + DY LVM+ + G + SL T+ S E L Sbjct: 618 AQEESAFVAKLYYAFQSRDYLYLVMEFMNGGDCASLLKSL-YTIPESWAKIYIAEVALGL 676 Query: 924 EKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQH 1073 E LH G +H D+KP+N L+ G L LGL ++ G++ Sbjct: 677 EHLHRLGIIHRDIKPDNILMSITGHLKLADFGLSQLGLTTRQLRLQKGKN 726
>Q7TT50:MRCKB_MOUSE Serine/threonine-protein kinase MRCK beta - Mus musculus (Mouse)| Length = 1713 Score = 47.8 bits (112), Expect = 2e-04 Identities = 57/226 (25%), Positives = 95/226 (42%), Gaps = 4/226 (1%) Frame = +3 Query: 558 HSPQYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFE--HRNSKGCNYGPPYE 731 H +++ + +G+G FG+V V + + TER A ++ K+E R C + Sbjct: 72 HREDFEIIKVIGRGAFGEVAVVKMRN--TERIY--AMKILNKWEMLKRAETAC-----FR 122 Query: 732 WQVYSSLNG-CYGIPWVHYKGRQGDYYVLVMDI-LGPSLWDVWNSLGQTMTPSMVACIAV 905 + +NG C I +HY + +Y LVMD +G L + + + M Sbjct: 123 EERDVLVNGDCQWITALHYAFQDENYLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYIG 182 Query: 906 EAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYD 1085 E + ++ +H +VH D+KP+N LL G + L D G K + + Q Sbjct: 183 EMVLAIDSIHQLHYVHRDIKPDNVLLDVNG-----HIRLADFGSCLKMNDDGTVQSSVAV 237 Query: 1086 QRPDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPW 1223 PD I A + +G+ G D SL + +L G P+ Sbjct: 238 GTPDYISPEILQA-MEDGMGKYGP-ECDWWSLGVCMYEMLYGETPF 281
>Q07174:M3K8_MOUSE Mitogen-activated protein kinase kinase kinase 8 - Mus musculus| (Mouse) Length = 467 Score = 47.8 bits (112), Expect = 2e-04 Identities = 49/176 (27%), Positives = 74/176 (42%), Gaps = 3/176 (1%) Frame = +3 Query: 921 LEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDI 1100 L+ LH+K +H D+KP N + K L+D GL+ K E P Sbjct: 241 LDFLHSKKVIHHDIKPSNIVFMST------KAVLVDFGLSVKMTEDV--------YLPKD 286 Query: 1101 FRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPW--QGYQGDNKSFLVCKKKM 1274 RGT Y S L R S + D+ SL TLI + G PW + + S+L K Sbjct: 287 LRGTEIYMSPEVILCRGHSTKADIYSLGATLIHMQTGTPPWVKRYPRSAYPSYLYIIHKQ 346 Query: 1275 SISPDLMCCYCAPPFKLFLETVTNMKFDEEPNY-PKLISLFDELIEPQHLRPIRID 1439 + + + C+P + +E + PN+ PK +L++ + L P R D Sbjct: 347 APPLEDIAGDCSPGMRELIEAA----LERNPNHRPKAA----DLLKHEALNPPRED 394
>O14328:KSP1_SCHPO Serine/threonine-protein kinase ksp1 - Schizosaccharomyces pombe| (Fission yeast) Length = 474 Score = 47.8 bits (112), Expect = 2e-04 Identities = 49/169 (28%), Positives = 74/169 (43%), Gaps = 8/169 (4%) Frame = +3 Query: 570 YKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYSS 749 YKVER L KG +G V + R+ RT P + LK+ + K Y E + Sbjct: 9 YKVERPLNKGSYGTVVLAHRLF----RT-PRCKD--LKYAIKCIKKPAYTFLQEVNILRQ 61 Query: 750 LNGCYGIPWVHYKGRQGD--YYVLVMDILGPSLWDVWNSL------GQTMTPSMVACIAV 905 L+ +H+ D YY +V++ L D++ + P M+ I + Sbjct: 62 LSRSRHRNIIHFVESFEDNVYYYVVLEYC--PLGDLYECILNNDFPNAKNQPEMIKNIFL 119 Query: 906 EAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWK 1052 + I + LH+ G H D+KPENFLL E + + D GLA + K Sbjct: 120 QIIDGVAHLHSHGIYHRDLKPENFLLSLSEDGSELVVKISDFGLACRDK 168
>Q64682:ARBK1_MESAU Beta-adrenergic receptor kinase 1 - Mesocricetus auratus (Golden| hamster) Length = 689 Score = 47.8 bits (112), Expect = 2e-04 Identities = 60/231 (25%), Positives = 95/231 (41%), Gaps = 5/231 (2%) Frame = +3 Query: 570 YKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYS- 746 + V R +G+GGFG+VY R+ G + +K + + N E + S Sbjct: 191 FSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALN-----ERIMLSL 245 Query: 747 -SLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISIL 923 S C I + Y R D ++D++ S + + + A E I L Sbjct: 246 VSTGDCPFIVCMSYAFRTPDNLSFILDLMNGGDLHYHLSQHGVFSEADMRSYAAEIILGL 305 Query: 924 EKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLA---SKWKETSSGQHVDYDQRP 1094 E +H + V+ D+KP N LL + G + + DLGLA SK K +S Y P Sbjct: 306 EHMHNRFVVYRDLKPANILLDEHG-----HVRISDLGLACDFSKKKPHASVGTHGY-MAP 359 Query: 1095 DIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNK 1247 ++ + + Y S D SL L LLRG P++ ++ +K Sbjct: 360 EVLQKGVAYDS-----------SADWFSLGCMLFKLLRGHSPFRQHKTKDK 399
>Q9XA16:PKNX_STRCO Probable serine/threonine-protein kinase SCO3848 - Streptomyces| coelicolor Length = 673 Score = 47.4 bits (111), Expect = 3e-04 Identities = 55/230 (23%), Positives = 99/230 (43%), Gaps = 9/230 (3%) Frame = +3 Query: 567 QYKVERKLGKGGFGQVY------VGRRVSGGTERTG---PDAYEVALKFEHRNSKGCNYG 719 +Y++ LG+GG +VY +GR+V+ T R +++ + E +++ N+ Sbjct: 10 RYELGPVLGRGGMAEVYHAHDTRLGRQVAVKTLRADLARDPSFQARFRREAQSAASLNH- 68 Query: 720 PPYEWQVYSSLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACI 899 P VY + Y Y+++ + G +L ++ +S G+ + P + Sbjct: 69 -PAIVAVYDTGED--------YIDNVSIPYIVMEYVDGSTLRELLHS-GRKLLPERTLEM 118 Query: 900 AVEAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVD 1079 + + LE H G VH D+KP N +L + G ++ ++D G+A ++ + Sbjct: 119 TIGILQALEYSHRAGIVHRDIKPANVMLTRNG-----QVKVMDFGIARAMGDSG----MT 169 Query: 1080 YDQRPDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQG 1229 Q + GT +Y S G R DL S L LL R P+ G Sbjct: 170 MTQTAAVI-GTAQYLSPEQAKGEQVDARSDLYSTGCLLYELLTVRPPFVG 218
>Q8XJL8:PKN2_CLOPE Probable serine/threonine protein kinase CPE1738 - Clostridium| perfringens Length = 685 Score = 47.4 bits (111), Expect = 3e-04 Identities = 41/148 (27%), Positives = 66/148 (44%), Gaps = 1/148 (0%) Frame = +3 Query: 789 GRQGDYYVLVMDIL-GPSLWDVWNSLGQTMTPSMVACIAVEAISILEKLHAKGFVHGDVK 965 G Q D +VM+ + G +L D+ G + + I ++ LE H G +H DVK Sbjct: 77 GTQDDINYIVMEYVEGKTLKDIIKEKG-ALPYEVAISIGIKVAKALECAHKSGIIHRDVK 135 Query: 966 PENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFRGTIRYASVHAHLG 1145 P+N L+ + G + + D G+A K ++S+ H + G+ Y S G Sbjct: 136 PQNILVTEEG-----VVKVTDFGIA-KSMDSSTIAHT------NSVMGSAHYFSPEQAKG 183 Query: 1146 RTGSRRDDLESLAYTLIFLLRGRLPWQG 1229 R DL SL L ++ G +P+ G Sbjct: 184 TYTDYRTDLYSLGIVLYEMVTGVVPFNG 211
>Q9Z2A0:PDPK1_MOUSE 3-phosphoinositide-dependent protein kinase 1 - Mus musculus (Mouse)| Length = 559 Score = 47.4 bits (111), Expect = 3e-04 Identities = 32/107 (29%), Positives = 49/107 (45%) Frame = +3 Query: 906 EAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYD 1085 E +S LE LH KG +H D+KPEN LL ++ + + D G A S Sbjct: 191 EIVSALEYLHGKGIIHRDLKPENILLN-----EDMHIQITDFGTAKVLSPESK------Q 239 Query: 1086 QRPDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQ 1226 R + F GT +Y S ++ + DL +L + L+ G P++ Sbjct: 240 ARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFR 286
>Q96QS6:KPSH2_HUMAN Serine/threonine-protein kinase H2 - Homo sapiens (Human)| Length = 385 Score = 47.4 bits (111), Expect = 3e-04 Identities = 62/261 (23%), Positives = 103/261 (39%), Gaps = 12/261 (4%) Frame = +3 Query: 477 KMDGVSPEKIGG---GEDDASPVPEKVQVGHS---------PQYKVERKLGKGGFGQVYV 620 K +G + +GG G + A+ +++QV +Y ++ +G G F +V Sbjct: 20 KHEGQNQAGVGGAGPGPEAAAQAAQRIQVARFRAKFDPRVLARYDIKALIGTGSFSRVV- 78 Query: 621 GRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYSSLNGCYGIPWVHYKGRQG 800 RV T + P A +V E + C E V ++ Y + + + Sbjct: 79 --RVEQKTTKK-PFAIKVMETREREGREAC----VSELSVLRRVSHRYIVQLMEIFETED 131 Query: 801 DYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISILEKLHAKGFVHGDVKPENFL 980 Y+++ G L+D + G V + + A I LHA H ++KPEN L Sbjct: 132 QVYMVMELATGGELFDRLIAQGSFTERDAVRILQMVADGI-RYLHALQITHRNLKPENLL 190 Query: 981 LGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFRGTIRYASVHAHLGRTGSR 1160 PG +E K+ + D GLA K++ D GT Y + L + + Sbjct: 191 YYHPG--EESKILITDFGLAYSGKKSG-------DWTMKTLCGTPEYIAPEVLLRKPYTS 241 Query: 1161 RDDLESLAYTLIFLLRGRLPW 1223 D+ +L LL G LP+ Sbjct: 242 AVDMWALGVITYALLSGFLPF 262
>Q4WHP3:STE20_ASPFU Serine/threonine-protein kinase ste20 - Aspergillus fumigatus| (Sartorya fumigata) Length = 815 Score = 47.0 bits (110), Expect = 4e-04 Identities = 58/231 (25%), Positives = 94/231 (40%), Gaps = 8/231 (3%) Frame = +3 Query: 801 DYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISILEKLHAKGFVHGDVKPENFL 980 D +V++ + G SL DV MT +A + E ++ L+ LH+KG +H D+K +N L Sbjct: 603 DLWVVMEYMEGGSLTDVVTF--NIMTEGQIAAVCRETLNGLQHLHSKGVIHRDIKSDNIL 660 Query: 981 LGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFRGTIRYASVHAHLGRTGSR 1160 L G+ + L D G + Q D + + GT + + + R Sbjct: 661 LSLDGN-----IKLTDFGFCA--------QINDSQNKRNTMVGTPYWMAPEVVTRKEYGR 707 Query: 1161 RDDLESLAYTLIFLLRGRLPWQGYQGDNKSFLVCKKKMSISPDLMCCYCAPPFKLFLETV 1340 + D+ SL I ++ G P+ +L+ D +P F+ FL Sbjct: 708 KVDIWSLGIMAIEMIEGEPPYLTESPLRALYLIATNGTPTIKDEH--NLSPVFRDFLHLA 765 Query: 1341 TNMKFDEEPN---YPKLISLFDELIEP-QHLRPI----RIDGALKAGQKRG 1469 +K D E + L+ F L P HL P+ R+ A + QK G Sbjct: 766 --LKVDPEKRASAHDLLMHPFMSLCSPLTHLAPLVKAARLSRAQEKAQKGG 814
>O53510:PKNL_MYCTU Probable serine/threonine-protein kinase pknL - Mycobacterium| tuberculosis Length = 399 Score = 47.0 bits (110), Expect = 4e-04 Identities = 44/155 (28%), Positives = 66/155 (42%), Gaps = 4/155 (2%) Frame = +3 Query: 777 VHYKGRQGDYYVLVMDIL-GPSLWDVWNSLGQTMTPSMVACIAVEAISILEKLHAKGFVH 953 V+ +G+ G + LVM+++ G +L ++ G M P V + + L H G VH Sbjct: 82 VYDQGKDGRHPFLVMELIEGGTLRELLIERGP-MPPHAVVAVLRPVLGGLAAAHRAGLVH 140 Query: 954 GDVKPENFLLGQPGSPDEKKLFLIDLGL---ASKWKETSSGQHVDYDQRPDIFRGTIRYA 1124 DVKPEN L+ D+ + L D GL + TS+G + GT Y Sbjct: 141 RDVKPENILIS-----DDGDVKLADFGLVRAVAAASITSTG----------VILGTAAYL 185 Query: 1125 SVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQG 1229 S R D+ S+ + LL G P+ G Sbjct: 186 SPEQVRDGNADPRSDVYSVGVLVYELLTGHTPFTG 220
>Q7TYY6:PKNL_MYCBO Probable serine/threonine-protein kinase pknL - Mycobacterium bovis| Length = 399 Score = 47.0 bits (110), Expect = 4e-04 Identities = 44/155 (28%), Positives = 66/155 (42%), Gaps = 4/155 (2%) Frame = +3 Query: 777 VHYKGRQGDYYVLVMDIL-GPSLWDVWNSLGQTMTPSMVACIAVEAISILEKLHAKGFVH 953 V+ +G+ G + LVM+++ G +L ++ G M P V + + L H G VH Sbjct: 82 VYDQGKDGRHPFLVMELIEGGTLRELLIERGP-MPPHAVVAVLRPVLGGLAAAHRAGLVH 140 Query: 954 GDVKPENFLLGQPGSPDEKKLFLIDLGL---ASKWKETSSGQHVDYDQRPDIFRGTIRYA 1124 DVKPEN L+ D+ + L D GL + TS+G + GT Y Sbjct: 141 RDVKPENILIS-----DDGDVKLADFGLVRAVAAASITSTG----------VILGTAAYL 185 Query: 1125 SVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQG 1229 S R D+ S+ + LL G P+ G Sbjct: 186 SPEQVRDGNADPRSDVYSVGVLVYELLTGHTPFTG 220
>P65728:PKNG_MYCTU Probable serine/threonine-protein kinase pknG - Mycobacterium| tuberculosis Length = 750 Score = 47.0 bits (110), Expect = 4e-04 Identities = 57/205 (27%), Positives = 88/205 (42%), Gaps = 10/205 (4%) Frame = +3 Query: 567 QYKVERKLGKGGFGQVYVG--RRVSG------GTERTGPDAYEVALKFEHRNSKGCNYGP 722 QY+V+ + GG G +Y+ R V+G G +G DA A+ R P Sbjct: 150 QYEVKGCIAHGGLGWIYLALDRNVNGRPVVLKGLVHSG-DAEAQAMAMAERQFLAEVVHP 208 Query: 723 PYEWQVYSSLNGCYGIPWVHYKGRQGDY--YVLVMDILGPSLWDVWNSLGQTMTPSMVAC 896 Q+++ +V + R GD Y+++ + G SL S GQ + + Sbjct: 209 SIV-QIFN---------FVEHTDRHGDPVGYIVMEYVGGQSLK---RSKGQKLPVAEAIA 255 Query: 897 IAVEAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHV 1076 +E + L LH+ G V+ D+KPEN +L E++L LIDLG S+ Sbjct: 256 YLLEILPALSYLHSIGLVYNDLKPENIML------TEEQLKLIDLGAVSRINSFGYLYGT 309 Query: 1077 DYDQRPDIFRGTIRYASVHAHLGRT 1151 Q P+I R A+ +GRT Sbjct: 310 PGFQAPEIVRTGPTVATDIYTVGRT 334
>P65729:PKNG_MYCBO Probable serine/threonine-protein kinase pknG - Mycobacterium bovis| Length = 750 Score = 47.0 bits (110), Expect = 4e-04 Identities = 57/205 (27%), Positives = 88/205 (42%), Gaps = 10/205 (4%) Frame = +3 Query: 567 QYKVERKLGKGGFGQVYVG--RRVSG------GTERTGPDAYEVALKFEHRNSKGCNYGP 722 QY+V+ + GG G +Y+ R V+G G +G DA A+ R P Sbjct: 150 QYEVKGCIAHGGLGWIYLALDRNVNGRPVVLKGLVHSG-DAEAQAMAMAERQFLAEVVHP 208 Query: 723 PYEWQVYSSLNGCYGIPWVHYKGRQGDY--YVLVMDILGPSLWDVWNSLGQTMTPSMVAC 896 Q+++ +V + R GD Y+++ + G SL S GQ + + Sbjct: 209 SIV-QIFN---------FVEHTDRHGDPVGYIVMEYVGGQSLK---RSKGQKLPVAEAIA 255 Query: 897 IAVEAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHV 1076 +E + L LH+ G V+ D+KPEN +L E++L LIDLG S+ Sbjct: 256 YLLEILPALSYLHSIGLVYNDLKPENIML------TEEQLKLIDLGAVSRINSFGYLYGT 309 Query: 1077 DYDQRPDIFRGTIRYASVHAHLGRT 1151 Q P+I R A+ +GRT Sbjct: 310 PGFQAPEIVRTGPTVATDIYTVGRT 334
>P18653:KS6A1_MOUSE Ribosomal protein S6 kinase alpha-1 - Mus musculus (Mouse)| Length = 724 Score = 47.0 bits (110), Expect = 4e-04 Identities = 47/190 (24%), Positives = 87/190 (45%), Gaps = 5/190 (2%) Frame = +3 Query: 567 QYKVERKLGKGGFGQVYVGRRVSGGTERTGPDA---YEVALKFEHRNSKGCNYGPPYEWQ 737 Q+++ + LG+G FG+V++ R+V T PD+ Y + + + E Sbjct: 61 QFELLKVLGQGSFGKVFLVRKV------TRPDSGHLYAMKVLKKATLKVRDRVRTKMERD 114 Query: 738 VYSSLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTM--TPSMVACIAVEA 911 + + +N + + +HY + L++D L D++ L + + T V E Sbjct: 115 ILADVNHPFVVK-LHYAFQTEGKLYLILDFLRGG--DLFTRLSKEVMFTEEDVKFYLAEL 171 Query: 912 ISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQR 1091 L+ LH+ G ++ D+KPEN LL + G + L D GL S + +D++++ Sbjct: 172 ALGLDHLHSLGIIYRDLKPENILLDEEG-----HIKLTDFGL--------SKEAIDHEKK 218 Query: 1092 PDIFRGTIRY 1121 F GT+ Y Sbjct: 219 AYSFCGTVEY 228
>Q12236:KOK0_YEAST Probable serine/threonine-protein kinase YOL100W - Saccharomyces| cerevisiae (Baker's yeast) Length = 1081 Score = 47.0 bits (110), Expect = 4e-04 Identities = 36/130 (27%), Positives = 54/130 (41%), Gaps = 3/130 (2%) Frame = +3 Query: 900 AVEAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETS---SGQ 1070 A + I ++ LH+ G +H D+KPEN LL E K+ L D G A T+ S Sbjct: 284 AAQIIDAIDYLHSNGIIHRDIKPENILL-----DGEMKIKLTDFGTAKLLNPTNNSVSKP 338 Query: 1071 HVDYDQRPDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNKS 1250 D R F GT Y S R D+ + L ++ G+ P++ Sbjct: 339 EYDLSTRSKSFVGTAEYVSPELLNDSFTDYRCDIWAFGCILFQMIAGKPPFKA----TNE 394 Query: 1251 FLVCKKKMSI 1280 +L +K M + Sbjct: 395 YLTFQKVMKV 404
>Q7YRC6:AURKB_BOVIN Serine/threonine-protein kinase 12 - Bos taurus (Bovine)| Length = 344 Score = 47.0 bits (110), Expect = 4e-04 Identities = 60/245 (24%), Positives = 94/245 (38%), Gaps = 4/245 (1%) Frame = +3 Query: 570 YKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNS---KGCNYGPPYEWQV 740 +++ R LGKG FG VY+ R + VALK ++ +G + E ++ Sbjct: 77 FEIGRPLGKGKFGNVYLAREKKSH--------FIVALKVLFKSQIEKEGVEHQLRREIEI 128 Query: 741 YSSLNGCYGIPWVHY-KGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAIS 917 + L + +Y R+ Y +L G ++ S +T A I E Sbjct: 129 QAHLQHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKS--RTFDEQRTATIMEELAD 186 Query: 918 ILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPD 1097 L HAK +H D+KPEN LLG G +L + D G W + R Sbjct: 187 ALTYCHAKKVIHRDIKPENLLLGLRG-----ELKIADFG----WSVHAP------SLRRK 231 Query: 1098 IFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNKSFLVCKKKMS 1277 GT+ Y GRT + + DL + LL G P++ + + K + Sbjct: 232 TMCGTLDYLPPEMIEGRTHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLK 291 Query: 1278 ISPDL 1292 P + Sbjct: 292 FPPSV 296
>O97627:ARBK1_DIDMA Beta-adrenergic receptor kinase 1 - Didelphis marsupialis virginiana| (North American opossum) Length = 689 Score = 47.0 bits (110), Expect = 4e-04 Identities = 60/231 (25%), Positives = 95/231 (41%), Gaps = 5/231 (2%) Frame = +3 Query: 570 YKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYS- 746 + V R +G+GGFG+VY R+ G + +K + + N E + S Sbjct: 191 FSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALN-----ERIMLSL 245 Query: 747 -SLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISIL 923 S C I + Y D ++D++ S + S + A E I L Sbjct: 246 VSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSESDMRFYAAEIILGL 305 Query: 924 EKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLA---SKWKETSSGQHVDYDQRP 1094 E +H++ V+ D+KP N LL + G + + DLGLA SK K +S Y P Sbjct: 306 EHMHSRFVVYRDLKPANILLDEFG-----HVRISDLGLACDFSKKKPHASVGTHGY-MAP 359 Query: 1095 DIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNK 1247 ++ + + Y S D SL L LLRG P++ ++ +K Sbjct: 360 EVLQKGVAYDS-----------SADWFSLGCMLFKLLRGHSPFRQHKTKDK 399
>Q03306:PKH3_YEAST Serine/threonine-protein kinase PKH3 - Saccharomyces cerevisiae| (Baker's yeast) Length = 898 Score = 46.6 bits (109), Expect = 5e-04 Identities = 43/173 (24%), Positives = 73/173 (42%), Gaps = 10/173 (5%) Frame = +3 Query: 765 GIPWVHYKGRQGDYYVLVMDIL-GPSLWDVWNSLGQTMTPSMVACIAVEAISILEKLHAK 941 GI ++Y + V+D G L + + +G T + I LE +H+ Sbjct: 74 GIIKLYYTFHDEENLYFVLDFAPGGELLSLLHKMG-TFNDIWTRHFTAQLIDALEFIHSH 132 Query: 942 GFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDY---------DQRP 1094 G +H D+KPEN LL + G +L + D G A+ + SG + +Q Sbjct: 133 GIIHRDLKPENVLLDRDG-----RLMITDFGAAATIDPSLSGDSAKFNSDSNGSKDNQNC 187 Query: 1095 DIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNKSF 1253 F GT Y S L D+ +L + ++G+ P++G + + K+F Sbjct: 188 ASFVGTAEYVSPELLLYNQCGYGSDIWALGCMIYQFVQGQPPFRG-ENELKTF 239
>Q9Z1M4:KS6B2_MOUSE Ribosomal protein S6 kinase beta-2 - Mus musculus (Mouse)| Length = 485 Score = 46.6 bits (109), Expect = 5e-04 Identities = 61/237 (25%), Positives = 98/237 (41%), Gaps = 2/237 (0%) Frame = +3 Query: 588 LGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYSSLNGCYG 767 LGKGG+G+V+ R+V G T A +V K + S E + S+ + Sbjct: 73 LGKGGYGKVFQVRKVQG-TNLGKIYAMKVLRKAKIVCSAKDTAHTRAERNILESVKHPFI 131 Query: 768 IPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISI-LEKLHAKG 944 + + G Y+++ + G L+ G + + AC + I++ L LH+ G Sbjct: 132 VELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDT--ACFYLAEITLALGHLHSHG 189 Query: 945 FVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFRGTIRYA 1124 ++ D+KPEN +L G + L D GL + + H F GTI Y Sbjct: 190 IIYRDLKPENIMLSSQG-----HIKLTDFGLCKESIHEGAITHT--------FCGTIEYM 236 Query: 1125 SVHAHLGRTG-SRRDDLESLAYTLIFLLRGRLPWQGYQGDNKSFLVCKKKMSISPDL 1292 + L RTG +R D SL + +L G P+ + K K+ + P L Sbjct: 237 APEI-LVRTGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIKGKLVLPPYL 292
>P36616:DSK1_SCHPO Protein kinase dsk1 - Schizosaccharomyces pombe (Fission yeast)| Length = 544 Score = 46.6 bits (109), Expect = 5e-04 Identities = 44/157 (28%), Positives = 70/157 (44%), Gaps = 15/157 (9%) Frame = +3 Query: 558 HSPQYKVERKLGKGGFGQVYVG------RRVSGGTER-------TGPDAYEVALKFEHRN 698 H +Y VERKLG G F V++ RRV+ R T D + K + Sbjct: 77 HHRRYVVERKLGWGHFSTVWLAYDRAAKRRVALKVVRSAEHYRETSIDEIRILQKIREGD 136 Query: 699 SKGCNYGPPYEWQVYSSLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMT 878 K + + S L+ + ++G G + +V ++LG +L + S G Sbjct: 137 EKHLG-----KKHIISLLD------YFVHRGPNGAHVCMVFEVLGENLLSLIQSYGHRGV 185 Query: 879 P-SMVACIAVEAISILEKLHAK-GFVHGDVKPENFLL 983 P +V IA + + L+ LH + G +H D+KPEN L+ Sbjct: 186 PVGIVKQIAYQLLIALDYLHRECGIIHTDLKPENVLI 222
>P83510:TNIK_MOUSE Traf2 and NCK-interacting protein kinase - Mus musculus (Mouse)| Length = 916 Score = 46.2 bits (108), Expect = 7e-04 Identities = 74/329 (22%), Positives = 129/329 (39%), Gaps = 10/329 (3%) Frame = +3 Query: 570 YKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYSS 749 +++ +G G +GQVY GR V G + +V E + N Y + + Sbjct: 25 FELVELVGNGTYGQVYKGRHVKTG-QLAAIKVMDVTGDEEEEIKQEINMLKKYSH--HRN 81 Query: 750 LNGCYGIPWVHYKGRQGDYYVLVMDILGP-SLWD-VWNSLGQTMTPSMVACIAVEAISIL 923 + YG D LVM+ G S+ D + N+ G T+ +A I E + L Sbjct: 82 IATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGL 141 Query: 924 EKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQH----VDYDQR 1091 LH +H D+K +N LL + ++ L+D G++++ T ++ Y Sbjct: 142 SHLHQHKVIHRDIKGQNVLL-----TENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMA 196 Query: 1092 PDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNKSFLVCKKK 1271 P++ + + T + DL SL T I + G P FL+ + Sbjct: 197 PEVI-------ACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMRALFLIPRNP 249 Query: 1272 MSISPDLMCCYCAPPFKLFLETVTNMKFDEEPNYPKLISLFDELIEPQHLRPIRI---DG 1442 +P L + F+ F+E+ + P +L+ + + + R +RI D Sbjct: 250 ---APRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMK-HPFIRDQPNERQVRIQLKDH 305 Query: 1443 ALKAGQKRGRVSHEEDEQPRKKVRL-GSP 1526 + +KRG E E + + GSP Sbjct: 306 IDRTKKKRGEKDETEYEYSGSECKSEGSP 334
>Q9Y7J6:PPK21_SCHPO Serine/threonine-protein kinase ppk21 - Schizosaccharomyces pombe| (Fission yeast) Length = 550 Score = 46.2 bits (108), Expect = 7e-04 Identities = 39/131 (29%), Positives = 59/131 (45%) Frame = +3 Query: 900 AVEAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVD 1079 A E +S +E +H+ G +H D+KPEN L G+ K + D G A K D Sbjct: 159 AAEILSSIEYMHSCGIIHRDLKPENILF--DGNMHVK---ITDFGTA-KILPPKYVNSPD 212 Query: 1080 YDQRPDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNKSFLV 1259 Y P F GT Y + + S+ DL + A + ++ G P+ G +N + Sbjct: 213 YTTFPSSFVGTAEYVAPELLSRQVVSKSSDLWAFACVVYQMIVGSPPFHGSNPNN----I 268 Query: 1260 CKKKMSISPDL 1292 KK MS+ +L Sbjct: 269 FKKIMSLEYEL 279
>Q9H4B4:PLK3_HUMAN Serine/threonine-protein kinase PLK3 - Homo sapiens (Human)| Length = 646 Score = 46.2 bits (108), Expect = 7e-04 Identities = 54/235 (22%), Positives = 94/235 (40%) Frame = +3 Query: 570 YKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYSS 749 Y R LGKGGF + Y G+ + + H+ K N E +++ Sbjct: 62 YLKGRLLGKGGFARCYEATDTETGSAYAVKVIPQSRVAKPHQREKILN-----EIELHRD 116 Query: 750 LNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISILEK 929 L + + + H+ + Y+ + SL +W + + P V + +S L+ Sbjct: 117 LQHRHIVRFSHHFEDADNIYIFLELCSRKSLAHIWKARHTLLEPE-VRYYLRQILSGLKY 175 Query: 930 LHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFRG 1109 LH +G +H D+K NF + + +L + D GLA++ + +QR G Sbjct: 176 LHQRGILHRDLKLGNFFI-----TENMELKVGDFGLAARLEPP--------EQRKKTICG 222 Query: 1110 TIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNKSFLVCKKKM 1274 T Y + L + D+ SL + LL G P++ D K C K++ Sbjct: 223 TPNYVAPEVLLRQGHGPEADVWSLGCVMYTLLCGSPPFE--TADLKETYRCIKQV 275
>P49695:PKWA_THECU Probable serine/threonine-protein kinase pkwA - Thermomonospora| curvata Length = 742 Score = 46.2 bits (108), Expect = 7e-04 Identities = 57/226 (25%), Positives = 83/226 (36%), Gaps = 3/226 (1%) Frame = +3 Query: 555 GHSPQYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEW 734 G Y++ +LG GG GQV++ R G P +V L E+ N E Sbjct: 11 GRIGPYRLVSRLGAGGMGQVFLARSPGGR-----PVVVKVILP-EYANDDEYRIRFAREV 64 Query: 735 QVYSSLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAI 914 + + G + + ++ I GPSL G + + + +A + Sbjct: 65 EAARRVGGFHTAQVIDADPTADPPWMATAYIPGPSLRKAVTERGP-LYGNNLRTLAAGLV 123 Query: 915 SILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKE---TSSGQHVDYD 1085 L +HA G VH D KP N +L G +ID G+A T SG + Sbjct: 124 EGLAAIHACGLVHRDFKPSNIVLAADGPR------VIDFGVARPLDSSVMTQSGAVI--- 174 Query: 1086 QRPDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPW 1223 GT+ Y S G D+ SL L F GR P+ Sbjct: 175 -------GTLAYMSPEQTDGSQVGPASDVFSLGTVLAFAATGRSPF 213
>Q9S2C0:PKSC_STRCO Serine/threonine protein kinase pksC - Streptomyces coelicolor| Length = 556 Score = 46.2 bits (108), Expect = 7e-04 Identities = 35/109 (32%), Positives = 53/109 (48%) Frame = +3 Query: 897 IAVEAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHV 1076 I + ++ LE H G VH D+KP N ++ + G + ++D G+A + SG V Sbjct: 131 ITADVLAALEISHEMGLVHRDIKPGNVMMTKRGV-----VKVMDFGIA---RAMQSG--V 180 Query: 1077 DYDQRPDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPW 1223 + + GT +Y S LGR R DL S+ L L+ GRLP+ Sbjct: 181 TSMTQTGMVVGTPQYLSPEQALGRGVDARSDLYSVGIMLFQLVTGRLPF 229
>Q9P1W9:PIM2_HUMAN Serine/threonine-protein kinase Pim-2 - Homo sapiens (Human)| Length = 311 Score = 46.2 bits (108), Expect = 7e-04 Identities = 39/151 (25%), Positives = 67/151 (44%), Gaps = 12/151 (7%) Frame = +3 Query: 567 QYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGP-------P 725 +Y++ LGKGGFG V+ G R++ D +VA+K RN + + P P Sbjct: 31 EYRLGPLLGKGGFGTVFAGHRLT--------DRLQVAIKVIPRN-RVLGWSPLSDSVTCP 81 Query: 726 YEWQVYSSLNGCYGIPWV-----HYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMV 890 E + + G P V ++ ++G VL + L+D G + Sbjct: 82 LEVALLWKVGAGGGHPGVIRLLDWFETQEGFMLVLERPLPAQDLFDYITEKG-PLGEGPS 140 Query: 891 ACIAVEAISILEKLHAKGFVHGDVKPENFLL 983 C + ++ ++ H++G VH D+K EN L+ Sbjct: 141 RCFFGQVVAAIQHCHSRGVVHRDIKDENILI 171
>Q9Y5S2:MRCKB_HUMAN Serine/threonine-protein kinase MRCK beta - Homo sapiens (Human)| Length = 1711 Score = 46.2 bits (108), Expect = 7e-04 Identities = 56/226 (24%), Positives = 95/226 (42%), Gaps = 4/226 (1%) Frame = +3 Query: 558 HSPQYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFE--HRNSKGCNYGPPYE 731 H +++ + +G+G FG+V V + + TER A ++ K+E R C + Sbjct: 72 HREDFEIIKVIGRGAFGEVAVVKMKN--TERIY--AMKILNKWEMLKRAETAC-----FR 122 Query: 732 WQVYSSLNG-CYGIPWVHYKGRQGDYYVLVMDI-LGPSLWDVWNSLGQTMTPSMVACIAV 905 + +NG C I +HY + ++ LVMD +G L + + + M Sbjct: 123 EERDVLVNGDCQWITALHYAFQDENHLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYIG 182 Query: 906 EAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYD 1085 E + ++ +H +VH D+KP+N LL G + L D G K + + Q Sbjct: 183 EMVLAIDSIHQLHYVHRDIKPDNVLLDVNG-----HIRLADFGSCLKMNDDGTVQSSVAV 237 Query: 1086 QRPDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPW 1223 PD I A + +G+ G D SL + +L G P+ Sbjct: 238 GTPDYISPEILQA-MEDGMGKYGP-ECDWWSLGVCMYEMLYGETPF 281
>Q9JM52:MINK1_MOUSE Misshapen-like kinase 1 - Mus musculus (Mouse)| Length = 1308 Score = 46.2 bits (108), Expect = 7e-04 Identities = 73/317 (23%), Positives = 123/317 (38%), Gaps = 9/317 (2%) Frame = +3 Query: 570 YKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYSS 749 +++ +G G +GQVY GR V G + +V E + N Y + + Sbjct: 25 FELVEVVGNGTYGQVYKGRHVKTG-QLAAIKVMDVTEDEEEEIKQEINMLKKYSH--HRN 81 Query: 750 LNGCYGIPWVHYKGRQGDYYVLVMDILGP-SLWD-VWNSLGQTMTPSMVACIAVEAISIL 923 + YG D LVM+ G S+ D V N+ G + +A I E + L Sbjct: 82 IATYYGAFIKKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNALKEDCIAYICREILRGL 141 Query: 924 EKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQH----VDYDQR 1091 LHA +H D+K +N LL + ++ L+D G++++ T ++ Y Sbjct: 142 AHLHAHKVIHRDIKGQNVLL-----TENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMA 196 Query: 1092 PDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNKSFLVCKKK 1271 P++ + + T R D+ SL T I + G P FL+ + Sbjct: 197 PEVI-------ACDENPDATYDYRSDIWSLGITAIEMAEGAPPLCDMHPMRALFLIPRNP 249 Query: 1272 MSISPDLMCCYCAPPFKLFLETVTNMKFDEEPNYPKLISLFDELIEPQHLRPIRI---DG 1442 P L + F F++T + P +L+ F + + R +RI D Sbjct: 250 ---PPRLKSKKWSKKFTDFIDTCLIKTYLSRPPTEQLLK-FPFIRDQPTERQVRIQLKDH 305 Query: 1443 ALKAGQKRGRVSHEEDE 1493 ++ +KRG E E Sbjct: 306 IDRSRKKRGEKEETEYE 322
>Q63562:M3K8_RAT Mitogen-activated protein kinase kinase kinase 8 - Rattus norvegicus| (Rat) Length = 467 Score = 46.2 bits (108), Expect = 7e-04 Identities = 48/176 (27%), Positives = 74/176 (42%), Gaps = 3/176 (1%) Frame = +3 Query: 921 LEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDI 1100 L+ LH+K +H D+KP N + K L+D GL+ + E P Sbjct: 241 LDFLHSKKVIHHDIKPSNIVFMST------KAVLVDFGLSVQMTEDV--------YLPKD 286 Query: 1101 FRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPW--QGYQGDNKSFLVCKKKM 1274 RGT Y S L R S + D+ SL TLI + G PW + + S+L K Sbjct: 287 LRGTEIYMSPEVILCRGHSTKADIYSLGATLIHMQTGTPPWVKRYPRSAYPSYLYIIHKQ 346 Query: 1275 SISPDLMCCYCAPPFKLFLETVTNMKFDEEPNY-PKLISLFDELIEPQHLRPIRID 1439 + + + C+P + +E + PN+ PK +L++ + L P R D Sbjct: 347 APPLEDIAGDCSPGMRELIEAA----LERNPNHRPKAA----DLLKHEALNPPRED 394
>P53894:CBK1_YEAST Serine/threonine-protein kinase CBK1 - Saccharomyces cerevisiae| (Baker's yeast) Length = 756 Score = 46.2 bits (108), Expect = 7e-04 Identities = 36/147 (24%), Positives = 66/147 (44%), Gaps = 6/147 (4%) Frame = +3 Query: 771 PWV---HYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISILEKLHAK 941 PWV +Y + Y L+M+ L Q T + E I +E +H Sbjct: 410 PWVVSLYYSFQDAQYLYLIMEFLPGGDLMTMLIRWQLFTEDVTRFYMAECILAIETIHKL 469 Query: 942 GFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKET-SSGQHVDYDQRPDIFRGTIR 1118 GF+H D+KP+N L+ G + L D GL++ + +T S + Q+ + G + Sbjct: 470 GFIHRDIKPDNILIDIRG-----HIKLSDFGLSTGFHKTHDSNYYKKLLQQDEATNGISK 524 Query: 1119 YASVHAHLGRTGSRRDDL--ESLAYTL 1193 + +A+ T ++R + +S++ T+ Sbjct: 525 PGTYNANTTDTANKRQTMVVDSISLTM 551
>Q9UKE5:TNIK_HUMAN TRAF2 and NCK-interacting protein kinase - Homo sapiens (Human)| Length = 1360 Score = 45.8 bits (107), Expect = 0.001 Identities = 71/317 (22%), Positives = 124/317 (39%), Gaps = 9/317 (2%) Frame = +3 Query: 570 YKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYSS 749 +++ +G G +GQVY GR V G + +V E + N Y + + Sbjct: 25 FELVELVGNGTYGQVYKGRHVKTG-QLAAIKVMDVTGDEEEEIKQEINMLKKYSH--HRN 81 Query: 750 LNGCYGIPWVHYKGRQGDYYVLVMDILGP-SLWD-VWNSLGQTMTPSMVACIAVEAISIL 923 + YG D LVM+ G S+ D + N+ G T+ +A I E + L Sbjct: 82 IATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGL 141 Query: 924 EKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQH----VDYDQR 1091 LH +H D+K +N LL + ++ L+D G++++ T ++ Y Sbjct: 142 SHLHQHKVIHRDIKGQNVLL-----TENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMA 196 Query: 1092 PDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNKSFLVCKKK 1271 P++ + + T + DL SL T I + G P FL+ + Sbjct: 197 PEVI-------ACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMRALFLIPRNP 249 Query: 1272 MSISPDLMCCYCAPPFKLFLETVTNMKFDEEPNYPKLISLFDELIEPQHLRPIRI---DG 1442 +P L + F+ F+E+ + P +L+ + + + R +RI D Sbjct: 250 ---APRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMK-HPFIRDQPNERQVRIQLKDH 305 Query: 1443 ALKAGQKRGRVSHEEDE 1493 + +KRG E E Sbjct: 306 IDRTKKKRGEKDETEYE 322
>Q9Y6E0:STK24_HUMAN Serine/threonine-protein kinase 24 - Homo sapiens (Human)| Length = 443 Score = 45.8 bits (107), Expect = 0.001 Identities = 77/334 (23%), Positives = 131/334 (39%), Gaps = 7/334 (2%) Frame = +3 Query: 585 KLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKF-EHRNSKGCNYGPPYEWQVYSSLNGC 761 K+GKG FG+V+ G + T++ VA+K + ++ E V S + Sbjct: 41 KIGKGSFGEVFKG--IDNRTQKV------VAIKIIDLEEAEDEIEDIQQEITVLSQCDSP 92 Query: 762 YGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISILEKLHAK 941 Y + + ++++ + G S D+ + + +A I E + L+ LH++ Sbjct: 93 YVTKYYGSYLKDTKLWIIMEYLGGGSALDLLEP--GPLDETQIATILREILKGLDYLHSE 150 Query: 942 GFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFRGTIRY 1121 +H D+K N LL + G ++ L D G+A GQ D + + F GT + Sbjct: 151 KKIHRDIKAANVLLSEHG-----EVKLADFGVA--------GQLTDTQIKRNTFVGTPFW 197 Query: 1122 ASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNKSFLVCKKKMSISPDLMCC 1301 + + D+ SL T I L RG P FL+ K +P + Sbjct: 198 MAPEVIKQSAYDSKADIWSLGITAIELARGEPPHSELHPMKVLFLIPKN----NPPTLEG 253 Query: 1302 YCAPPFKLFLETVTNMKFDEEPNYPKLIS---LFDELIEPQHLRPIRID--GALKAGQKR 1466 + P K F+E N + P +L+ + + +L + ID KA Q Sbjct: 254 NYSKPLKEFVEACLNKEPSFRPTAKELLKHKFILRNAKKTSYLTEL-IDRYKRWKAEQSH 312 Query: 1467 GRVSHEE-DEQPRKKVRLGSPANQWISVYNAKRP 1565 S E+ D + + GS + WI K P Sbjct: 313 DDSSSEDSDAETDGQASGGSDSGDWIFTIREKDP 346
>Q2VWQ3:STE20_PENMA Serine/threonine-protein kinase pakA - Penicillium marneffei| Length = 642 Score = 45.8 bits (107), Expect = 0.001 Identities = 37/141 (26%), Positives = 63/141 (44%) Frame = +3 Query: 801 DYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISILEKLHAKGFVHGDVKPENFL 980 D +V++ + G SL DV M+ +A + E +S L+ LH+KG +H D+K +N L Sbjct: 430 DLWVVMEYMEGGSLTDVVTF--NIMSEGQIAAVCRETLSGLQHLHSKGVIHRDIKSDNIL 487 Query: 981 LGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFRGTIRYASVHAHLGRTGSR 1160 L G ++ L D G + Q D + + GT + + + R Sbjct: 488 LSMDG-----EIKLTDFGFCA--------QINDSQNKRNTMVGTPYWMAPEVVTRKEYGR 534 Query: 1161 RDDLESLAYTLIFLLRGRLPW 1223 + D+ SL I ++ G P+ Sbjct: 535 KVDIWSLGIMAIEMIEGEPPY 555
>Q7RZD3:STE20_NEUCR Serine/threonine-protein kinase ste-20 - Neurospora crassa| Length = 954 Score = 45.8 bits (107), Expect = 0.001 Identities = 37/142 (26%), Positives = 62/142 (43%) Frame = +3 Query: 798 GDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISILEKLHAKGFVHGDVKPENF 977 G+ +V++ + G SL DV MT +A + E + L+ LH+KG +H D+K +N Sbjct: 742 GELWVVMEYMEGGSLTDVVTF--NIMTEGQIASVCRETLRGLQHLHSKGVIHRDIKSDNI 799 Query: 978 LLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFRGTIRYASVHAHLGRTGS 1157 LL G+ + L D G + E S + GT + + + Sbjct: 800 LLSMEGN-----IKLTDFGFCATINEAQS--------KRTTMVGTPYWMAPEVVTRKEYG 846 Query: 1158 RRDDLESLAYTLIFLLRGRLPW 1223 R+ D+ SL I ++ G P+ Sbjct: 847 RKVDIWSLGIMAIEMIEGEPPY 868
>Q75DK7:STE20_ASHGO Serine/threonine-protein kinase STE20 - Ashbya gossypii (Yeast)| (Eremothecium gossypii) Length = 971 Score = 45.8 bits (107), Expect = 0.001 Identities = 28/89 (31%), Positives = 47/89 (52%) Frame = +3 Query: 795 QGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISILEKLHAKGFVHGDVKPEN 974 +GD +V++ + G SL DV +T +A ++ E + L LH+KG +H D+K +N Sbjct: 750 KGDLWVIMEYMEGGSLTDVVTHC--ILTEGQIAAVSRETLRGLHFLHSKGVIHRDIKSDN 807 Query: 975 FLLGQPGSPDEKKLFLIDLGLASKWKETS 1061 LL G+ + L D G ++ ET+ Sbjct: 808 ILLSMDGN-----IKLTDFGFCAQINETN 831
>Q63644:ROCK1_RAT Rho-associated protein kinase 1 - Rattus norvegicus (Rat)| Length = 1369 Score = 45.8 bits (107), Expect = 0.001 Identities = 45/164 (27%), Positives = 73/164 (44%), Gaps = 5/164 (3%) Frame = +3 Query: 570 YKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEH-RNSKGCNYGPPYEWQVYS 746 Y+V + +G+G FG+V + R S T + A ++ KFE + S + + ++ Sbjct: 76 YEVVKVIGRGAFGEVQLVRHKS--TRKVY--AMKLLSKFEMIKRSDSAFFWEERDIMAFA 131 Query: 747 SLNGCYGIPWV---HYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACI-AVEAI 914 + PWV Y + Y +VM+ + D+ N + P A E + Sbjct: 132 NS------PWVVQLFYAFQDDRYLYMVMEYMPGG--DLVNLMSNYDVPEKWARFYTAEVV 183 Query: 915 SILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASK 1046 L+ +H+ GF+H DVKP+N LL + G L L D G K Sbjct: 184 LALDAIHSMGFIHRDVKPDNMLLDKSG-----HLKLADFGTCMK 222
>O77819:ROCK1_RABIT Rho-associated protein kinase 1 - Oryctolagus cuniculus (Rabbit)| Length = 1354 Score = 45.8 bits (107), Expect = 0.001 Identities = 45/164 (27%), Positives = 73/164 (44%), Gaps = 5/164 (3%) Frame = +3 Query: 570 YKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEH-RNSKGCNYGPPYEWQVYS 746 Y+V + +G+G FG+V + R S T + A ++ KFE + S + + ++ Sbjct: 76 YEVVKVIGRGAFGEVQLVRHKS--TRKVY--AMKLLSKFEMIKRSDSAFFWEERDIMAFA 131 Query: 747 SLNGCYGIPWV---HYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACI-AVEAI 914 + PWV Y + Y +VM+ + D+ N + P A E + Sbjct: 132 NS------PWVVQLFYAFQDDRYLYMVMEYMPGG--DLVNLMSNYDVPEKWARFYTAEVV 183 Query: 915 SILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASK 1046 L+ +H+ GF+H DVKP+N LL + G L L D G K Sbjct: 184 LALDAIHSMGFIHRDVKPDNMLLDKSG-----HLKLADFGTCMK 222
>P70335:ROCK1_MOUSE Rho-associated protein kinase 1 - Mus musculus (Mouse)| Length = 1354 Score = 45.8 bits (107), Expect = 0.001 Identities = 45/164 (27%), Positives = 73/164 (44%), Gaps = 5/164 (3%) Frame = +3 Query: 570 YKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEH-RNSKGCNYGPPYEWQVYS 746 Y+V + +G+G FG+V + R S T + A ++ KFE + S + + ++ Sbjct: 76 YEVVKVIGRGAFGEVQLVRHKS--TRKVY--AMKLLSKFEMIKRSDSAFFWEERDIMAFA 131 Query: 747 SLNGCYGIPWV---HYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACI-AVEAI 914 + PWV Y + Y +VM+ + D+ N + P A E + Sbjct: 132 NS------PWVVQLFYAFQDDRYLYMVMEYMPGG--DLVNLMSNYDVPEKWARFYTAEVV 183 Query: 915 SILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASK 1046 L+ +H+ GF+H DVKP+N LL + G L L D G K Sbjct: 184 LALDAIHSMGFIHRDVKPDNMLLDKSG-----HLKLADFGTCMK 222
>Q13464:ROCK1_HUMAN Rho-associated protein kinase 1 - Homo sapiens (Human)| Length = 1354 Score = 45.8 bits (107), Expect = 0.001 Identities = 45/164 (27%), Positives = 73/164 (44%), Gaps = 5/164 (3%) Frame = +3 Query: 570 YKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEH-RNSKGCNYGPPYEWQVYS 746 Y+V + +G+G FG+V + R S T + A ++ KFE + S + + ++ Sbjct: 76 YEVVKVIGRGAFGEVQLVRHKS--TRKVY--AMKLLSKFEMIKRSDSAFFWEERDIMAFA 131 Query: 747 SLNGCYGIPWV---HYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACI-AVEAI 914 + PWV Y + Y +VM+ + D+ N + P A E + Sbjct: 132 NS------PWVVQLFYAFQDDRYLYMVMEYMPGG--DLVNLMSNYDVPEKWARFYTAEVV 183 Query: 915 SILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASK 1046 L+ +H+ GF+H DVKP+N LL + G L L D G K Sbjct: 184 LALDAIHSMGFIHRDVKPDNMLLDKSG-----HLKLADFGTCMK 222
>Q9HFF4:PPK1_SCHPO Serine/threonine-protein kinase ppk1 - Schizosaccharomyces pombe| (Fission yeast) Length = 1023 Score = 45.8 bits (107), Expect = 0.001 Identities = 53/229 (23%), Positives = 99/229 (43%), Gaps = 11/229 (4%) Frame = +3 Query: 570 YKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPY-EWQVYS 746 Y + R +G G FG+V +G + +V +K + C E + Sbjct: 492 YILGRTIGTGEFGKVKLGWPLPKANSTIHRSTPQVVIKIVLSTKQNCQTSRLMREVAILK 551 Query: 747 SL--NGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVAC-IAVEAIS 917 L N + + ++ + + + +++ + G L+D L + VAC + + IS Sbjct: 552 GLGNNHPHIVKYLDFVKTKHHFGIVLDYVNGGELFDY--ILARRRLEDSVACRLFAQLIS 609 Query: 918 ILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSS-GQHVDYDQRP 1094 + LH++G VH D+K EN LL + + + D G A+ + ++ +H ++P Sbjct: 610 GVAYLHSRGVVHRDLKLENILL-----DTNRNIVIADFGFATTFGHFNTLSEHSLPTEKP 664 Query: 1095 DIFR---GTIRYAS---VHAHLGRTGSRRDDLESLAYTLIFLLRGRLPW 1223 D+F G+ YA+ V+ G + D+ S L +L G LP+ Sbjct: 665 DLFSTSCGSPCYAAPELVNCKSGMYAGTQADIWSCGVILYAMLAGYLPF 713
>Q9R011:PLK3_RAT Serine/threonine-protein kinase PLK3 - Rattus norvegicus (Rat)| Length = 615 Score = 45.8 bits (107), Expect = 0.001 Identities = 61/261 (23%), Positives = 104/261 (39%), Gaps = 1/261 (0%) Frame = +3 Query: 495 PEKIGGGED-DASPVPEKVQVGHSPQYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYE 671 PE + G + DAS + + G + Y R LGKGGF + Y + Sbjct: 7 PEVLAGPQTPDASRLITDPRSGRT--YIKGRLLGKGGFARCYEATDTETSIAYAVKVIPQ 64 Query: 672 VALKFEHRNSKGCNYGPPYEWQVYSSLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDV 851 + H+ K N E +++ L + + + H+ + Y+ + SL + Sbjct: 65 SRVAKPHQREKIIN-----EIELHRDLQHRHIVRFSHHFEDADNIYIFLELCSRKSLAHI 119 Query: 852 WNSLGQTMTPSMVACIAVEAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDL 1031 W + + P V + +S L+ LH +G +H D+K NF + D +L + D Sbjct: 120 WKARHTLLEPE-VRYYLRQILSGLKYLHQRGILHRDLKLGNFFI-----TDNMELKVGDF 173 Query: 1032 GLASKWKETSSGQHVDYDQRPDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRG 1211 GLA++ + +QR GT Y + L + D+ SL + LL G Sbjct: 174 GLAARLEPP--------EQRKKTICGTPNYVAPEVLLRQGHGPEADVWSLGCVMYTLLCG 225 Query: 1212 RLPWQGYQGDNKSFLVCKKKM 1274 P++ D K C K++ Sbjct: 226 SPPFE--TADLKETYRCIKQV 244
>O43077:MDE3_SCHPO Sporulation protein kinase mde3 - Schizosaccharomyces pombe (Fission| yeast) Length = 559 Score = 45.8 bits (107), Expect = 0.001 Identities = 50/173 (28%), Positives = 79/173 (45%), Gaps = 6/173 (3%) Frame = +3 Query: 534 VPEKVQVGHSPQYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYE-VALKFEHRNSKGC 710 V + QV +Y V++KLG G FG VY+ +R E+ G YE VA+K +SK Sbjct: 9 VLDLTQVIFEDRYLVKQKLGDGSFGTVYLAQR----KEKNG--LYETVAVKKLKNSSKPK 62 Query: 711 NYGPPYEWQVYSSLNGCYGIPW-VHYKGRQGDYY---VLVMDILGPSLWDVWNSL-GQTM 875 + + +L P + D Y LVM+ + +L+ ++ G+ Sbjct: 63 PKHELLKLRESLALRKISKHPCLIDLLETFMDPYRNIFLVMEFMDCNLFQLFKRRQGRLF 122 Query: 876 TPSMVACIAVEAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLG 1034 T I ++ IS +E +H GF+H D+KPEN L+ + + I LG Sbjct: 123 TKETAFNILLQIISGIEHIHKHGFMHRDIKPENILVKRISPKPISSRYSIKLG 175
>Q39008:M3K1_ARATH Mitogen-activated protein kinase kinase kinase 1 - Arabidopsis| thaliana (Mouse-ear cress) Length = 608 Score = 45.8 bits (107), Expect = 0.001 Identities = 63/274 (22%), Positives = 117/274 (42%), Gaps = 7/274 (2%) Frame = +3 Query: 588 LGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYSSLNGCYG 767 LG+G FG VY G +SG + EV+L + ++ C E ++ S L Sbjct: 339 LGRGSFGSVYEG--ISGDGDFFA--VKEVSLLDQGSQAQECIQQLEGEIKLLSQLQHQN- 393 Query: 768 IPWVHYKGRQGD---YYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISILEKLHA 938 V Y+G D Y+ + + SL ++ + S+V+ + + L+ LH Sbjct: 394 --IVRYRGTAKDGSNLYIFLELVTQGSLLKLYQRY--QLRDSVVSLYTRQILDGLKYLHD 449 Query: 939 KGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLA--SKWKETSSGQHVDYDQRPDIF--R 1106 KGF+H D+K N L+ G+ + L D GLA SK+ + S + + P++ + Sbjct: 450 KGFIHRDIKCANILVDANGA-----VKLADFGLAKVSKFNDIKSCKGTPFWMAPEVINRK 504 Query: 1107 GTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNKSFLVCKKKMSISP 1286 + Y S D+ SL T++ + G++P+ + F + + + P Sbjct: 505 DSDGYGS-----------PADIWSLGCTVLEMCTGQIPYSDLEPVQALFRIGRGTLPEVP 553 Query: 1287 DLMCCYCAPPFKLFLETVTNMKFDEEPNYPKLIS 1388 D + + +LF+ + +E P +L++ Sbjct: 554 DTL----SLDARLFILKCLKVNPEERPTAAELLN 583
>P35626:ARBK2_HUMAN Beta-adrenergic receptor kinase 2 - Homo sapiens (Human)| Length = 688 Score = 45.8 bits (107), Expect = 0.001 Identities = 56/230 (24%), Positives = 90/230 (39%), Gaps = 3/230 (1%) Frame = +3 Query: 567 QYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYS 746 ++ V R +G+GGFG+VY R+ G + +K + + N E + S Sbjct: 190 EFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALN-----ERIMLS 244 Query: 747 --SLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISI 920 S C I + Y D ++D++ S + + A E I Sbjct: 245 LVSTGDCPFIVCMTYAFHTPDKLCFILDLMNGGDLHYHLSQHGVFSEKEMRFYATEIILG 304 Query: 921 LEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDI 1100 LE +H + V+ D+KP N LL + G + DLGLA + + ++P Sbjct: 305 LEHMHNRFVVYRDLKPANILLDEHGHAR-----ISDLGLACDFSK----------KKPHA 349 Query: 1101 FRGTIRYASVHA-HLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNK 1247 GT Y + G D SL L LLRG P++ ++ +K Sbjct: 350 SVGTHGYMAPEVLQKGTAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDK 399
>Q99MK8:ARBK1_MOUSE Beta-adrenergic receptor kinase 1 - Mus musculus (Mouse)| Length = 689 Score = 45.8 bits (107), Expect = 0.001 Identities = 57/229 (24%), Positives = 91/229 (39%), Gaps = 3/229 (1%) Frame = +3 Query: 570 YKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYS- 746 + V R +G+GGFG+VY R+ G + +K + + N E + S Sbjct: 191 FSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALN-----ERIMLSL 245 Query: 747 -SLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISIL 923 S C I + Y D ++D++ S + + + A E I L Sbjct: 246 VSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFYAAEIILGL 305 Query: 924 EKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIF 1103 E +H + V+ D+KP N LL + G + + DLGLA + + +RP Sbjct: 306 EHMHNRFVVYRDLKPANILLDEHG-----HVRISDLGLACDFSK----------KRPHAS 350 Query: 1104 RGTIRYASVHA-HLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNK 1247 GT Y + G D SL L LLRG P++ ++ +K Sbjct: 351 VGTHGYMAPEVLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDK 399
>Q80UW5:MRCKG_MOUSE Serine/threonine-protein kinase MRCK gamma - Mus musculus (Mouse)| Length = 1551 Score = 45.4 bits (106), Expect = 0.001 Identities = 39/157 (24%), Positives = 62/157 (39%), Gaps = 15/157 (9%) Frame = +3 Query: 570 YKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYSS 749 +++ + +G+G FG+V V R+ G A+K H+ W++ Sbjct: 71 FEILKVIGRGAFGEVAVVRQRGSGQI--------FAMKMLHK------------WEMLKR 110 Query: 750 LN-GCY----------GIPWV---HYKGRQGDYYVLVMDIL-GPSLWDVWNSLGQTMTPS 884 C+ WV HY + +Y LVMD G L + + + P Sbjct: 111 AETACFREERDVLVKGDSRWVTALHYAFQDEEYLYLVMDYYAGGDLLTLLSRFEDRLPPE 170 Query: 885 MVACIAVEAISILEKLHAKGFVHGDVKPENFLLGQPG 995 + E + + LH G+VH DVKP+N LL G Sbjct: 171 LAQFYLAEMVLAIHSLHQLGYVHRDVKPDNILLDMNG 207
>Q8N4C8:MINK1_HUMAN Misshapen-like kinase 1 - Homo sapiens (Human)| Length = 1332 Score = 45.4 bits (106), Expect = 0.001 Identities = 73/317 (23%), Positives = 123/317 (38%), Gaps = 9/317 (2%) Frame = +3 Query: 570 YKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYSS 749 +++ +G G +GQVY GR V G + +V E + N Y + + Sbjct: 25 FELVEVVGNGTYGQVYKGRHVKTG-QLAAIKVMDVTEDEEEEIKQEINMLKKYSH--HRN 81 Query: 750 LNGCYGIPWVHYKGRQGDYYVLVMDILGP-SLWD-VWNSLGQTMTPSMVACIAVEAISIL 923 + YG D LVM+ G S+ D V N+ G + +A I E + L Sbjct: 82 IATYYGAFIKKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNALKEDCIAYICREILRGL 141 Query: 924 EKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQH----VDYDQR 1091 LHA +H D+K +N LL + ++ L+D G++++ T ++ Y Sbjct: 142 AHLHAHKVIHRDIKGQNVLL-----TENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMA 196 Query: 1092 PDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNKSFLVCKKK 1271 P++ + + T R D+ SL T I + G P FL+ + Sbjct: 197 PEVI-------ACDENPDATYDYRSDIWSLGITAIEMAEGAPPLCDMHPMRALFLIPRNP 249 Query: 1272 MSISPDLMCCYCAPPFKLFLETVTNMKFDEEPNYPKLISLFDELIEPQHLRPIRI---DG 1442 P L + F F++T + P +L+ F + + R +RI D Sbjct: 250 ---PPRLKSKKWSKKFIDFIDTCLIKTYLSRPPTEQLLK-FPFIRDQPTERQVRIQLKDH 305 Query: 1443 ALKAGQKRGRVSHEEDE 1493 ++ +KRG E E Sbjct: 306 IDRSRKKRGEKEETEYE 322
>Q9WUL6:M3K14_MOUSE Mitogen-activated protein kinase kinase kinase 14 - Mus musculus| (Mouse) Length = 942 Score = 45.4 bits (106), Expect = 0.001 Identities = 39/148 (26%), Positives = 65/148 (43%), Gaps = 1/148 (0%) Frame = +3 Query: 792 RQGDYYVLVMDIL-GPSLWDVWNSLGQTMTPSMVACIAVEAISILEKLHAKGFVHGDVKP 968 R+G + + M++L G SL + +G + +A+ LE LH + +HGDVK Sbjct: 462 REGPWVNIFMELLEGGSLGQLIKQMG-CLPEDRALYYLGQALEGLEYLHTRRILHGDVKA 520 Query: 969 ENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFRGTIRYASVHAHLGR 1148 +N LL GS + L D G A + G+ + D GT + + +G+ Sbjct: 521 DNVLLSSDGS----RAALCDFGHALCLQPDGLGKSL---LTGDYIPGTETHMAPEVVMGK 573 Query: 1149 TGSRRDDLESLAYTLIFLLRGRLPWQGY 1232 + D+ S ++ +L G PW Y Sbjct: 574 PCDAKVDIWSSCCMMLHMLNGCHPWTQY 601
>Q9UPZ9:ICK_HUMAN Serine/threonine-protein kinase ICK - Homo sapiens (Human)| Length = 632 Score = 45.4 bits (106), Expect = 0.001 Identities = 43/200 (21%), Positives = 81/200 (40%), Gaps = 13/200 (6%) Frame = +3 Query: 567 QYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYS 746 +Y R+LG G +G V +GR + G +A+K R Y W+ Sbjct: 3 RYTTIRQLGDGTYGSVLLGRSIESGEL--------IAIKKMKRKF--------YSWEECM 46 Query: 747 SLNGCYGIPWVHYKG--------RQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIA 902 +L + +++ R+ D+ + + + +L+ + + S + I Sbjct: 47 NLREVKSLKKLNHANVVKLKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIM 106 Query: 903 VEAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDY 1082 + + L +H GF H D+KPEN L P + + + D GLA + + S + DY Sbjct: 107 YQILQGLAFIHKHGFFHRDLKPENLLCMGP-----ELVKIADFGLAREIR--SKPPYTDY 159 Query: 1083 -----DQRPDIFRGTIRYAS 1127 + P++ + Y+S Sbjct: 160 VSTRWYRAPEVLLRSTNYSS 179
>P26818:ARBK2_BOVIN Beta-adrenergic receptor kinase 2 - Bos taurus (Bovine)| Length = 688 Score = 45.4 bits (106), Expect = 0.001 Identities = 56/229 (24%), Positives = 90/229 (39%), Gaps = 3/229 (1%) Frame = +3 Query: 570 YKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYS- 746 + V R +G+GGFG+VY R+ G + +K + + N E + S Sbjct: 191 FSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALN-----ERIMLSL 245 Query: 747 -SLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISIL 923 S C I + Y D ++D++ S + + A E I L Sbjct: 246 VSTGDCPFIVCMTYAFHTPDKLCFILDLMNGGDLHYHLSQHGVFSEKEMRFYATEIILGL 305 Query: 924 EKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIF 1103 E +H + V+ D+KP N LL + G + + DLGLA + + ++P Sbjct: 306 EHMHNRFVVYRDLKPANILLDEHG-----HVRISDLGLACDFSK----------KKPHAS 350 Query: 1104 RGTIRYASVHA-HLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNK 1247 GT Y + G D SL L LLRG P++ ++ +K Sbjct: 351 VGTHGYMAPEVLQKGTAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDK 399
>P26817:ARBK1_RAT Beta-adrenergic receptor kinase 1 - Rattus norvegicus (Rat)| Length = 689 Score = 45.4 bits (106), Expect = 0.001 Identities = 59/231 (25%), Positives = 94/231 (40%), Gaps = 5/231 (2%) Frame = +3 Query: 570 YKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYS- 746 + V R +G+GGFG+VY R+ G + +K + + N E + S Sbjct: 191 FSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALN-----ERIMLSL 245 Query: 747 -SLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISIL 923 S C I + Y D ++D++ S + + + A E I L Sbjct: 246 VSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFYAAEIILGL 305 Query: 924 EKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLA---SKWKETSSGQHVDYDQRP 1094 E +H + V+ D+KP N LL + G + + DLGLA SK K +S Y P Sbjct: 306 EHMHNRFVVYRDLKPANILLDEHG-----HVRISDLGLACDFSKKKPHASVGTHGY-MAP 359 Query: 1095 DIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNK 1247 ++ + + Y S D SL L LLRG P++ ++ +K Sbjct: 360 EVLQKGVAYDS-----------SADWFSLGCMLFKLLRGHSPFRQHKTKDK 399
>P25098:ARBK1_HUMAN Beta-adrenergic receptor kinase 1 - Homo sapiens (Human)| Length = 689 Score = 45.4 bits (106), Expect = 0.001 Identities = 59/231 (25%), Positives = 94/231 (40%), Gaps = 5/231 (2%) Frame = +3 Query: 570 YKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYS- 746 + V R +G+GGFG+VY R+ G + +K + + N E + S Sbjct: 191 FSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALN-----ERIMLSL 245 Query: 747 -SLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISIL 923 S C I + Y D ++D++ S + + + A E I L Sbjct: 246 VSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFYAAEIILGL 305 Query: 924 EKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLA---SKWKETSSGQHVDYDQRP 1094 E +H + V+ D+KP N LL + G + + DLGLA SK K +S Y P Sbjct: 306 EHMHNRFVVYRDLKPANILLDEHG-----HVRISDLGLACDFSKKKPHASVGTHGY-MAP 359 Query: 1095 DIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNK 1247 ++ + + Y S D SL L LLRG P++ ++ +K Sbjct: 360 EVLQKGVAYDS-----------SADWFSLGCMLFKLLRGHSPFRQHKTKDK 399
>P21146:ARBK1_BOVIN Beta-adrenergic receptor kinase 1 - Bos taurus (Bovine)| Length = 689 Score = 45.4 bits (106), Expect = 0.001 Identities = 59/231 (25%), Positives = 94/231 (40%), Gaps = 5/231 (2%) Frame = +3 Query: 570 YKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYS- 746 + V R +G+GGFG+VY R+ G + +K + + N E + S Sbjct: 191 FSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALN-----ERIMLSL 245 Query: 747 -SLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISIL 923 S C I + Y D ++D++ S + + + A E I L Sbjct: 246 VSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFYAAEIILGL 305 Query: 924 EKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLA---SKWKETSSGQHVDYDQRP 1094 E +H + V+ D+KP N LL + G + + DLGLA SK K +S Y P Sbjct: 306 EHMHNRFVVYRDLKPANILLDEHG-----HVRISDLGLACDFSKKKPHASVGTHGY-MAP 359 Query: 1095 DIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNK 1247 ++ + + Y S D SL L LLRG P++ ++ +K Sbjct: 360 EVLQKGVAYDS-----------SADWFSLGCMLFKLLRGHSPFRQHKTKDK 399
>O75716:STK16_HUMAN Serine/threonine-protein kinase 16 - Homo sapiens (Human)| Length = 305 Score = 45.1 bits (105), Expect = 0.002 Identities = 56/226 (24%), Positives = 97/226 (42%), Gaps = 17/226 (7%) Frame = +3 Query: 786 KGRQGDYYVLVMDILGPSLWDVWNSL---GQTMTPSMVACIAVEAISILEKLHAKGFVHG 956 +G + + ++L+ +LW+ L G +T + + + LE +HAKG+ H Sbjct: 88 RGAKHEAWLLLPFFKRGTLWNEIERLKDKGNFLTEDQILWLLLGICRGLEAIHAKGYAHR 147 Query: 957 DVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIF------RGTIR 1118 D+KP N LLG G P L+DLG ++ + HV+ ++ R TI Sbjct: 148 DLKPTNILLGDEGQP-----VLMDLGSMNQ-----ACIHVEGSRQALTLQDWAAQRCTIS 197 Query: 1119 YA-----SVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPW-QGYQGDNKSFLVCKKKMSI 1280 Y SV +H R D+ SL L ++ G P+ +Q + L + ++SI Sbjct: 198 YRAPELFSVQSHC--VIDERTDVWSLGCVLYAMMFGEGPYDMVFQKGDSVALAVQNQLSI 255 Query: 1281 --SPDLMCCYCAPPFKLFLETVTNMKFDEEPNYPKLISLFDELIEP 1412 SP + + L ++ + + P+ P L+S + L P Sbjct: 256 PQSP-----RHSSALRQLLNSMMTVDPHQRPHIPLLLSQLEALQPP 296
>P52497:SNF1_CANAL Carbon catabolite derepressing protein kinase - Candida albicans| (Yeast) Length = 620 Score = 45.1 bits (105), Expect = 0.002 Identities = 57/226 (25%), Positives = 96/226 (42%), Gaps = 7/226 (3%) Frame = +3 Query: 567 QYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNS--KGCNYGPPYEWQV 740 +Y++ + LG+G FG+V + + + G + VALK +R + K G Sbjct: 52 RYQILKTLGEGSFGKVKLAQHLGTGQK--------VALKIINRKTLAKSDMQGRVEREIS 103 Query: 741 YSSLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISI 920 Y L I ++ + D ++V++ G L+D G+ M + I+ Sbjct: 104 YLRLLRHPHIIKLYDVIKSKDEIIMVIEFAGKELFDYIVQRGK-MPEDEARRFFQQIIAA 162 Query: 921 LEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLAS-----KWKETSSGQHVDYD 1085 +E H VH D+KPEN LL D+ + + D GL++ + +TS G +Y Sbjct: 163 VEYCHRHKIVHRDLKPENLLL-----DDQLNVKIADFGLSNIMTDGNFLKTSCGS-PNYM 216 Query: 1086 QRPDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPW 1223 P++ G + YA D+ S L +L GRLP+ Sbjct: 217 PAPEVISGKL-YAGPEV----------DVWSAGVILYVMLCGRLPF 251
>Q9USX7:PPK22_SCHPO Serine/threonine-protein kinase ppk22 - Schizosaccharomyces pombe| (Fission yeast) Length = 526 Score = 45.1 bits (105), Expect = 0.002 Identities = 27/75 (36%), Positives = 40/75 (53%), Gaps = 2/75 (2%) Frame = +3 Query: 777 VHYKGRQGDYYVLVMDIL-GPSLWDVWNSLGQTMTPSMVACI-AVEAISILEKLHAKGFV 950 +++ + DY L M+ G + +SL + + P AC A E + LE LH GF+ Sbjct: 218 LYHSFQSRDYLYLCMEYCAGGEFFRALHSLPKHILPEKDACFYAAEVTAALEYLHLMGFI 277 Query: 951 HGDVKPENFLLGQPG 995 + D+KPEN LL Q G Sbjct: 278 YRDLKPENILLHQSG 292
>Q99640:PMYT1_HUMAN Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory| kinase - Homo sapiens (Human) Length = 499 Score = 45.1 bits (105), Expect = 0.002 Identities = 35/122 (28%), Positives = 56/122 (45%), Gaps = 3/122 (2%) Frame = +3 Query: 795 QGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISILEKLHAKGFVHGDVKPEN 974 +G L ++ GPSL + G ++ + V + + L LH++G VH DVKP N Sbjct: 179 EGGILYLQTELCGPSLQQHCEAWGASLPEAQVWGYLRDTLLALAHLHSQGLVHLDVKPAN 238 Query: 975 FLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQR---PDIFRGTIRYASVHAHLG 1145 LG G + L D GL + +G+ + D R P++ +G+ A+ LG Sbjct: 239 IFLGPRG-----RCKLGDFGLLVELGTAGAGEVQEGDPRYMAPELLQGSYGTAADVFSLG 293 Query: 1146 RT 1151 T Sbjct: 294 LT 295
>P0A5S4:PKNB_MYCTU Probable serine/threonine-protein kinase pknB - Mycobacterium| tuberculosis Length = 626 Score = 45.1 bits (105), Expect = 0.002 Identities = 38/141 (26%), Positives = 63/141 (44%) Frame = +3 Query: 807 YVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISILEKLHAKGFVHGDVKPENFLLG 986 Y+++ + G +L D+ ++ G MTP + +A L H G +H DVKP N ++ Sbjct: 89 YIVMEYVDGVTLRDIVHTEGP-MTPKRAIEVIADACQALNFSHQNGIIHRDVKPANIMIS 147 Query: 987 QPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFRGTIRYASVHAHLGRTGSRRD 1166 + + ++D G+A + SG V + GT +Y S G + R Sbjct: 148 ATNA-----VKVMDFGIARAIAD--SGNSV---TQTAAVIGTAQYLSPEQARGDSVDARS 197 Query: 1167 DLESLAYTLIFLLRGRLPWQG 1229 D+ SL L +L G P+ G Sbjct: 198 DVYSLGCVLYEVLTGEPPFTG 218
>P0A5S5:PKNB_MYCBO Probable serine/threonine-protein kinase pknB - Mycobacterium bovis| Length = 626 Score = 45.1 bits (105), Expect = 0.002 Identities = 38/141 (26%), Positives = 63/141 (44%) Frame = +3 Query: 807 YVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISILEKLHAKGFVHGDVKPENFLLG 986 Y+++ + G +L D+ ++ G MTP + +A L H G +H DVKP N ++ Sbjct: 89 YIVMEYVDGVTLRDIVHTEGP-MTPKRAIEVIADACQALNFSHQNGIIHRDVKPANIMIS 147 Query: 987 QPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFRGTIRYASVHAHLGRTGSRRD 1166 + + ++D G+A + SG V + GT +Y S G + R Sbjct: 148 ATNA-----VKVMDFGIARAIAD--SGNSV---TQTAAVIGTAQYLSPEQARGDSVDARS 197 Query: 1167 DLESLAYTLIFLLRGRLPWQG 1229 D+ SL L +L G P+ G Sbjct: 198 DVYSLGCVLYEVLTGEPPFTG 218
>P32491:MKK2_YEAST MAP kinase kinase MKK2/SSP33 - Saccharomyces cerevisiae (Baker's| yeast) Length = 506 Score = 45.1 bits (105), Expect = 0.002 Identities = 48/183 (26%), Positives = 81/183 (44%), Gaps = 11/183 (6%) Frame = +3 Query: 711 NYGPPYEWQVYSSL--NGCYGIPW-VHYKG-----RQGDYYVLVMDILGPSLWDVWNSL- 863 N P Y+ Q++ L N + + V Y G + Y+ + + G SL + +L Sbjct: 249 NTDPEYQKQIFRELQFNKSFKSDYIVQYYGMFTDEQSSSIYIAMEYMGGKSLEATYKNLL 308 Query: 864 --GQTMTPSMVACIAVEAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGL 1037 G ++ ++ IA + L LH + +H D+KP+N LL + G ++ L D G+ Sbjct: 309 KRGGRISERVIGKIAESVLRGLSYLHERKVIHRDIKPQNILLNEKG-----EIKLCDFGV 363 Query: 1038 ASKWKETSSGQHVDYDQRPDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRL 1217 SG+ V + F GT Y + G+ S D+ SL TL+ + GR Sbjct: 364 --------SGEAV--NSLAMTFTGTSFYMAPERIQGQPYSVTCDVWSLGLTLLEVAGGRF 413 Query: 1218 PWQ 1226 P++ Sbjct: 414 PFE 416
>P41279:M3K8_HUMAN Mitogen-activated protein kinase kinase kinase 8 - Homo sapiens| (Human) Length = 467 Score = 45.1 bits (105), Expect = 0.002 Identities = 46/175 (26%), Positives = 73/175 (41%), Gaps = 2/175 (1%) Frame = +3 Query: 921 LEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDI 1100 L+ LH+K +H D+KP N + K L+D GL+ + E P Sbjct: 241 LDFLHSKKVIHHDIKPSNIVFMST------KAVLVDFGLSVQMTEDV--------YFPKD 286 Query: 1101 FRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPW--QGYQGDNKSFLVCKKKM 1274 RGT Y S L R S + D+ SL TLI + G PW + + S+L K Sbjct: 287 LRGTEIYMSPEVILCRGHSTKADIYSLGATLIHMQTGTPPWVKRYPRSAYPSYLYIIHKQ 346 Query: 1275 SISPDLMCCYCAPPFKLFLETVTNMKFDEEPNYPKLISLFDELIEPQHLRPIRID 1439 + + + C+P + +E + PN+ + +L++ + L P R D Sbjct: 347 APPLEDIADDCSPGMRELIEA----SLERNPNHRPRAA---DLLKHEALNPPRED 394
>P53684:CDPK3_ORYSJ Calcium-dependent protein kinase, isoform 11 - Oryza sativa subsp.| japonica (Rice) Length = 542 Score = 45.1 bits (105), Expect = 0.002 Identities = 45/165 (27%), Positives = 74/165 (44%), Gaps = 4/165 (2%) Frame = +3 Query: 570 YKVERKLGKGGFGQVYVGRRVSGGTE---RTGPDAYEVALKFEHRNSKGCNYGPPYEWQV 740 Y + RKLG+G FG Y+ ++ G E +T P ++ K + + + E Q+ Sbjct: 79 YIIGRKLGQGQFGTTYLCTEINTGCEYACKTIPKR-KLITKEDVEDVRR-------EIQI 130 Query: 741 YSSLNGCYGIPWVHYKGRQGDYYVLVMDIL-GPSLWDVWNSLGQTMTPSMVACIAVEAIS 917 L+G + + G +VM++ G L+D G I + +S Sbjct: 131 MHHLSGHKNVVAIKDVYEDGQAVHIVMELCAGGELFDRIQEKGHYSERKAAELIRI-IVS 189 Query: 918 ILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWK 1052 I+ H+ G +H D+KPENFLL D+ + ID GL+ +K Sbjct: 190 IVAMCHSLGVMHRDLKPENFLL--LDKDDDLSIKAIDFGLSVFFK 232
>O70405:ULK1_MOUSE Serine/threonine-protein kinase ULK1 - Mus musculus (Mouse)| Length = 1051 Score = 44.7 bits (104), Expect = 0.002 Identities = 47/200 (23%), Positives = 86/200 (43%), Gaps = 10/200 (5%) Frame = +3 Query: 813 LVMDIL-GPSLWDVWNSLGQTMTPSMVACIAVEAISILEKLHAKGFVHGDVKPENFLLGQ 989 LVM+ G L D +++ +T++ V + + LH+KG +H D+KP+N LL Sbjct: 90 LVMEYCNGGDLADYLHTM-RTLSEDTVRLFLQQIAGAMRLLHSKGIIHRDLKPQNILLSN 148 Query: 990 PG----SPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFRGTIRYASVHAHLGRTGS 1157 PG +P ++ + D G A +++ + G+ Y + + + Sbjct: 149 PGGRRANPSNIRVKIADFGFA---------RYLQSNMMAATLCGSPMYMAPEVIMSQHYD 199 Query: 1158 RRDDLESLAYTLIFLLRGRLPWQGYQGDNKSFLVCKKKMSISPDLMCCYCAPPFKLFLET 1337 + DL S+ + L G+ P+Q + L +K ++ P + AP +L L Sbjct: 200 GKADLWSIGTIVYQCLTGKAPFQASSPQDLR-LFYEKNKTLVPAIPRETSAPLRQLLLAL 258 Query: 1338 V-----TNMKFDEEPNYPKL 1382 + M FDE ++P L Sbjct: 259 LQRNHKDRMDFDEFFHHPFL 278
>O88697:STK16_MOUSE Serine/threonine-protein kinase 16 - Mus musculus (Mouse)| Length = 305 Score = 44.7 bits (104), Expect = 0.002 Identities = 55/221 (24%), Positives = 93/221 (42%), Gaps = 12/221 (5%) Frame = +3 Query: 786 KGRQGDYYVLVMDILGPSLWDVWNSL---GQTMTPSMVACIAVEAISILEKLHAKGFVHG 956 +G + + ++L+ +LW+ L G +T + + + LE +HAKG+ H Sbjct: 88 RGAKHEAWLLLPFFKKGTLWNEIERLKDQGSFLTEDQILPLLLGISRGLEAIHAKGYAHR 147 Query: 957 DVKPENFLLGQPGSPDEKKLFLIDLG-LASKWKETSSGQHVDYDQRPDIFRGTIRYA--- 1124 D+KP N LLG G P L+DLG + + + Q R TI Y Sbjct: 148 DLKPTNILLGDEGQP-----VLMDLGSMNQACIQVEGSRQALALQDWAAQRCTISYRAPE 202 Query: 1125 --SVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPW-QGYQGDNKSFLVCKKKMSI--SPD 1289 SV +H R D+ SL L ++ G P+ +Q + L + ++SI SP Sbjct: 203 LFSVQSHC--VIDERTDVWSLGCVLYAMMFGEGPYDMVFQKGDSVALAVQNELSIPQSP- 259 Query: 1290 LMCCYCAPPFKLFLETVTNMKFDEEPNYPKLISLFDELIEP 1412 + + L ++ + + P+ P L+S + L P Sbjct: 260 ----RHSSALRQLLSSMMTVDPQQRPHIPVLLSQLEALQPP 296
>Q6C3D7:STE20_YARLI Serine/threonine-protein kinase STE20 - Yarrowia lipolytica (Candida| lipolytica) Length = 1125 Score = 44.7 bits (104), Expect = 0.002 Identities = 28/88 (31%), Positives = 46/88 (52%) Frame = +3 Query: 798 GDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISILEKLHAKGFVHGDVKPENF 977 GD +V++ + G SL DV MT S + + E + L+ LH+KG +H D+K +N Sbjct: 912 GDLWVVMEYMEGGSLTDVVTY--NMMTESQIGAVCRETLLGLQHLHSKGVIHRDIKSDNV 969 Query: 978 LLGQPGSPDEKKLFLIDLGLASKWKETS 1061 LL G ++ L D G ++ E++ Sbjct: 970 LLSMRG-----EIKLTDFGFCAQINESN 992
>Q5BBL3:STE20_EMENI Serine/threonine-protein kinase ste20 - Emericella nidulans| (Aspergillus nidulans) Length = 848 Score = 44.7 bits (104), Expect = 0.002 Identities = 57/232 (24%), Positives = 96/232 (41%), Gaps = 9/232 (3%) Frame = +3 Query: 801 DYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISILEKLHAKGFVHGDVKPENFL 980 D +V++ + G SL DV M+ +A + E ++ L+ LH+KG +H D+K +N L Sbjct: 636 DLWVVMEYMEGGSLTDVVTF--NIMSEPQIAAVCRETLNGLQHLHSKGVIHRDIKSDNIL 693 Query: 981 LGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFRGTIRYASVHAHLGRTGSR 1160 L G+ + L D G + Q D + + GT + + + R Sbjct: 694 LSLDGN-----IKLTDFGFCA--------QINDSQNKRNTMVGTPYWMAPEVVTRKEYGR 740 Query: 1161 RDDLESLAYTLIFLLRGRLPWQGYQGDNKSFLVCKK---KMSISPDLMCCYCAPPFKLFL 1331 + D+ SL I ++ G P+ +L+ K+ +L +P FK FL Sbjct: 741 KVDIWSLGIMAIEMIEGEPPYLTESPLRALYLIATNGTPKIKDEHNL-----SPVFKDFL 795 Query: 1332 ETVTNMKFDEEPNYPKLIS-LFDELIEP-QHLRPI----RIDGALKAGQKRG 1469 + ++ + L+ F L P HL P+ RI A + QK G Sbjct: 796 HFALRVDPEKRASAHDLLKHPFMNLCAPLNHLSPLVKAARISRAQEKAQKGG 847
>O75116:ROCK2_HUMAN Rho-associated protein kinase 2 - Homo sapiens (Human)| Length = 1388 Score = 44.7 bits (104), Expect = 0.002 Identities = 45/170 (26%), Positives = 71/170 (41%), Gaps = 7/170 (4%) Frame = +3 Query: 570 YKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVAL--KFEH-RNSKGCNYGPPYEWQV 740 Y V + +G+G FG+V + R + Y + L KFE + S + + Sbjct: 92 YDVVKVIGRGAFGEVQLVRH------KASQKVYAMKLLSKFEMIKRSDSAFFWEERDIMA 145 Query: 741 YSSLNGCYGIPWV---HYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACI-AVE 908 +++ PWV Y + Y +VM+ + D+ N + P A E Sbjct: 146 FANS------PWVVQLFYAFQDDRYLYMVMEYMPGG--DLVNLMSNYDVPEKWAKFYTAE 197 Query: 909 AISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKET 1058 + L+ +H+ G +H DVKP+N LL + G L L D G K ET Sbjct: 198 VVLALDAIHSMGLIHRDVKPDNMLLDKHG-----HLKLADFGTCMKMDET 242
>P54737:PKN5_MYXXA Serine/threonine-protein kinase pkn5 - Myxococcus xanthus| Length = 380 Score = 44.7 bits (104), Expect = 0.002 Identities = 35/105 (33%), Positives = 49/105 (46%), Gaps = 4/105 (3%) Frame = +3 Query: 921 LEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKE----TSSGQHVDYDQ 1088 L +H G VH D+KP N ++ D++++ L+D GLA + T +G+ V Sbjct: 232 LAYIHGHGLVHRDLKPSNIMV-----DDDRQVRLMDFGLAKFLADDAAITEAGKLV---- 282 Query: 1089 RPDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPW 1223 GT RY + LG R DL SL L LL GR P+ Sbjct: 283 ------GTYRYMAPEQILGEPLDGRADLYSLGVILYELLSGRPPF 321
>Q86V86:PIM3_HUMAN Serine/threonine-protein kinase Pim-3 - Homo sapiens (Human)| Length = 326 Score = 44.7 bits (104), Expect = 0.002 Identities = 62/258 (24%), Positives = 110/258 (42%), Gaps = 12/258 (4%) Frame = +3 Query: 570 YKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQV--- 740 Y+V LG GGFG VY G R++ G P A + +K E G G +V Sbjct: 40 YQVGAVLGSGGFGTVYAGSRIADGL----PVAVKHVVK-ERVTEWGSLGGATVPLEVVLL 94 Query: 741 --YSSLNGCYGIPWVHYKGRQGDYYVLVMDILGPS--LWDVWNSLGQTMTPSMVACIAVE 908 + G G+ + + D ++LV++ P+ L+D G P + + Sbjct: 95 RKVGAAGGARGVIRLLDWFERPDGFLLVLERPEPAQDLFDFITERGALDEP-LARRFFAQ 153 Query: 909 AISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQ 1088 ++ + H+ G VH D+K EN L+ +L LID G + K+T + D+D Sbjct: 154 VLAAVRHCHSCGVVHRDIKDENLLVDLRSG----ELKLIDFGSGALLKDT---VYTDFD- 205 Query: 1089 RPDIFRGTIRYA-----SVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNKSF 1253 GT Y+ H + GR+ + + SL L ++ G +P++ + + Sbjct: 206 ------GTRVYSPPEWIRYHRYHGRSAT----VWSLGVLLYDMVCGDIPFEQDEEILRGR 255 Query: 1254 LVCKKKMSISPDLMCCYC 1307 L+ ++++S + +C Sbjct: 256 LLFRRRVSPECQQLIRWC 273
>P32490:MKK1_YEAST MAP kinase kinase MKK1/SSP32 - Saccharomyces cerevisiae (Baker's| yeast) Length = 508 Score = 44.7 bits (104), Expect = 0.002 Identities = 58/244 (23%), Positives = 104/244 (42%), Gaps = 18/244 (7%) Frame = +3 Query: 711 NYGPPYEWQVYSSL--NGCYGIPW-VHYKGRQGD-----YYVLVMDILGPSLWDVWNSL- 863 N P Y+ Q++ L N + + V Y G D Y+ + + G SL ++ +L Sbjct: 256 NTDPEYQKQIFRELQFNRSFQSEYIVRYYGMFTDDENSSIYIAMEYMGGRSLDAIYKNLL 315 Query: 864 --GQTMTPSMVACIAVEAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGL 1037 G ++ ++ IA + L LH K +H D+KP+N LL + G ++ L D G+ Sbjct: 316 ERGGRISEKVLGKIAEAVLRGLSYLHEKKVIHRDIKPQNILLNENG-----QVKLCDFGV 370 Query: 1038 ASKWKETSSGQHVDYDQRPDIFRGTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRL 1217 SG+ V + F GT Y + G+ S D+ SL T++ + G+ Sbjct: 371 --------SGEAV--NSLATTFTGTSFYMAPERIQGQPYSVTSDVWSLGLTILEVANGKF 420 Query: 1218 PWQGYQ--GDNKSFLVCKKKMSISPDL-----MCCYCAPPFKLFLETVTNMKFDEEPNYP 1376 P + + F + ++ +P+L +P FK F++ E P+ Sbjct: 421 PCSSEKMAANIAPFELLMWILTFTPELKDEPESNIIWSPSFKSFIDYCLKKDSRERPSPR 480 Query: 1377 KLIS 1388 ++I+ Sbjct: 481 QMIN 484
>Q61846:MELK_MOUSE Maternal embryonic leucine zipper kinase - Mus musculus (Mouse)| Length = 643 Score = 44.7 bits (104), Expect = 0.002 Identities = 54/221 (24%), Positives = 93/221 (42%), Gaps = 3/221 (1%) Frame = +3 Query: 570 YKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGP-PYEWQVYS 746 Y++ +G GGF +V + V G VA+K +N+ G + E Sbjct: 11 YELYETIGTGGFAKVKLACHVLTGEM--------VAIKIMDKNALGSDLPRVKTEIDALK 62 Query: 747 SLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISILE 926 SL + H + ++++ G L+D S + ++ + + +S + Sbjct: 63 SLRHQHICQLYHVLETKNKIFMVLEYCPGGELFDYIISQDR-LSEEETRVVFRQILSAVA 121 Query: 927 KLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFR 1106 +H++G+ H D+KPEN L + KL LID GL +K K D Sbjct: 122 YVHSQGYAHRDLKPENLLF-----DENHKLKLIDFGLCAKPKGNK-------DYHLQTCC 169 Query: 1107 GTIRYASVHAHLGRT--GSRRDDLESLAYTLIFLLRGRLPW 1223 G++ YA+ G++ GS D+ S+ L L+ G LP+ Sbjct: 170 GSLAYAAPELIQGKSYLGSEA-DVWSMGILLYVLMCGFLPF 209
>Q12701:KSG1_SCHPO Serine/threonine-protein kinase ksg1 - Schizosaccharomyces pombe| (Fission yeast) Length = 592 Score = 44.7 bits (104), Expect = 0.002 Identities = 41/149 (27%), Positives = 65/149 (43%), Gaps = 9/149 (6%) Frame = +3 Query: 804 YYVLVMDILGPSLWDVWNSLGQ--TMTPSMVACIAVEAISILEKLHAKGFVHGDVKPENF 977 Y+VL + G L D N LG+ + A + V++I + +H +G +H D+KPEN Sbjct: 174 YFVLSLARNG-ELLDYINKLGRFNEICAQYYAALIVDSI---DYMHGRGVIHRDLKPENI 229 Query: 978 LLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPD-------IFRGTIRYASVHA 1136 LL D + + D G ++K +S G H + D F GT RY S Sbjct: 230 LL-----DDNMRTKITDFG-SAKILNSSHGSHEEDTHHADKPQAHSRSFVGTARYVSPEV 283 Query: 1137 HLGRTGSRRDDLESLAYTLIFLLRGRLPW 1223 + D+ + L +L G+ P+ Sbjct: 284 LSDKIAGTASDIWAFGCILFQMLAGKPPF 312
>Q18846:KS6A2_CAEEL Putative ribosomal protein S6 kinase alpha-2 - Caenorhabditis elegans| Length = 772 Score = 44.7 bits (104), Expect = 0.002 Identities = 68/277 (24%), Positives = 113/277 (40%), Gaps = 13/277 (4%) Frame = +3 Query: 567 QYKVERK----LGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEW 734 +YK+++ LGKG F V RV G + V+ KF + + E Sbjct: 377 KYKLDKSDAGLLGKGAFSVVRRCERVVDGAQFA---VKIVSQKFASQAQR--------EA 425 Query: 735 QVYSSLNGCYGIPWVHYKGRQGDYYVLVMDIL-GPSLWDVWNSLGQTMTPSMVACIAVEA 911 ++ + G I +H ++ LVM+IL G L + L + T S A I + Sbjct: 426 RILEMVQGHPNIVQLHDVHSDPLHFYLVMEILTGNELLERIRKL-ERFTESEAADIMRQL 484 Query: 912 ISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLA----SKWKETSSGQHVD 1079 +S ++ LH K VH D+KPEN L S +L L+D G A + ++ V Sbjct: 485 VSAVKYLHDKRIVHRDLKPENILFESIDS--SARLRLVDFGFARLLPNSMEQQLKSVQVL 542 Query: 1080 YDQRPDIFRGTIRYASVHA-HLGRTG---SRRDDLESLAYTLIFLLRGRLPWQGYQGDNK 1247 P T++YA+ +G + + + DL SL L +L G++P+ Sbjct: 543 RKMTPCF---TLQYAAPEVLDVGDSQPEYNEQCDLWSLGVVLFTMLSGQVPFH------- 592 Query: 1248 SFLVCKKKMSISPDLMCCYCAPPFKLFLETVTNMKFD 1358 + + + ++M C F + TN+ D Sbjct: 593 ----ARSRQESATEIMQRICRAEFSFTGDAWTNVSAD 625 Score = 44.3 bits (103), Expect = 0.003 Identities = 67/257 (26%), Positives = 104/257 (40%), Gaps = 3/257 (1%) Frame = +3 Query: 516 EDDASPVPEKVQVGHSPQYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHR 695 ED P EKV + + + + R LGKG +G+V++ R+V GG + A +V K Sbjct: 2 EDILMPEGEKVSMEN---FALLRVLGKGAYGKVFLVRKV-GGKDHNTIYAMKVLRKTRVL 57 Query: 696 NSKGCNYGPPYEWQVYSSLNGCYGIPWVHYKGRQGDYYVLVMD-ILGPSLWDVWNSLGQT 872 + E QV L G + + Y + +VM+ + G L+ S G Sbjct: 58 TKQKTLEHTMAERQVLERLRGTPFLVNLFYAFQTDTKLHIVMEYVRGGELFTHLCSRGHF 117 Query: 873 MTPSMVACIAVEAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWK 1052 + IA E + ++ LH + ++ D+K EN LL + G + L D GL+ + Sbjct: 118 DLEAARFVIA-ELVVAIDSLHQRKVIYRDLKLENILLDEEG-----HVKLTDFGLSKLFL 171 Query: 1053 ETSSGQHVDYDQRPDIFRGTIRYASVHAHLGRTGSRRD--DLESLAYTLIFLLRGRLPWQ 1226 R + + GTI Y S G D D SL LL G P+ Sbjct: 172 PGEL-------DRANSYCGTIEYMSPEVINRPEGGYSDVVDWWSLGVISFELLTGCSPFT 224 Query: 1227 GYQGDNKSFLVCKKKMS 1277 N S + K+ M+ Sbjct: 225 VDGAQNSSKDIAKRIMT 241
>P43249:GRK5_BOVIN G protein-coupled receptor kinase 5 - Bos taurus (Bovine)| Length = 590 Score = 44.7 bits (104), Expect = 0.002 Identities = 55/225 (24%), Positives = 88/225 (39%), Gaps = 5/225 (2%) Frame = +3 Query: 570 YKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYSS 749 ++ R LGKGGFG+V + + G + +K S N E Q+ Sbjct: 186 FRQYRVLGKGGFGEVCACQVRATGKMYACKRLEKKRIKKRKGESMALN-----EKQILEK 240 Query: 750 LNGCYGIPWVHYKGRQGDYYVLVMDIL--GPSLWDVWNSLGQTMTPSMVACIAVEAISIL 923 +N + + + Y D LV+ I+ G + ++N A E + L Sbjct: 241 VNSRFVVN-LAYAYETKDALCLVLTIMNGGDLKFHIYNMGNPGFEEERALFYAAEILCGL 299 Query: 924 EKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIF 1103 E LH + V+ D+KPEN LL G + + DLGLA K E D+ Sbjct: 300 EDLHHENIVYRDLKPENILLDDYG-----HIRISDLGLAVKIPE------------GDLI 342 Query: 1104 R---GTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQG 1229 R GT+ Y + + D L + ++ G+ P++G Sbjct: 343 RGRVGTVGYMAPEVLNNQRYGLSPDYWGLGCLIYEMIEGQSPFRG 387
>P49025:CTRO_MOUSE Citron Rho-interacting kinase - Mus musculus (Mouse)| Length = 2055 Score = 44.7 bits (104), Expect = 0.002 Identities = 28/94 (29%), Positives = 45/94 (47%), Gaps = 1/94 (1%) Frame = +3 Query: 768 IPWVHYKGRQGDYYVLVMDIL-GPSLWDVWNSLGQTMTPSMVACIAVEAISILEKLHAKG 944 IP + Y + + LVM+ G + N + SM+ E I + +H G Sbjct: 157 IPQLQYAFQDKNNLYLVMEYQPGGDFLSLLNRYEDQLDESMIQFYLAELILAVHSVHQMG 216 Query: 945 FVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASK 1046 +VH D+KPEN L+ + G ++ L+D G A+K Sbjct: 217 YVHRDIKPENILIDRTG-----EIKLVDFGSAAK 245
>P53681:CRK_DAUCA CDPK-related protein kinase - Daucus carota (Carrot)| Length = 602 Score = 44.7 bits (104), Expect = 0.002 Identities = 38/139 (27%), Positives = 62/139 (44%) Frame = +3 Query: 807 YVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISILEKLHAKGFVHGDVKPENFLLG 986 YV++ G L D S G T + ++ ++++ H +G VH D+KPENFL Sbjct: 226 YVVMELCEGGELLDRILSRGGKYTEDDAKAVMIQILNVVAFCHLQGVVHRDLKPENFLF- 284 Query: 987 QPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFRGTIRYASVHAHLGRTGSRRD 1166 ++ +L ID GL+ +V D+R + G+ Y + L R+ S Sbjct: 285 -KSKDEDSQLKAIDFGLS---------DYVKPDERLNDIVGSAYYVAPEV-LHRSYSTEA 333 Query: 1167 DLESLAYTLIFLLRGRLPW 1223 D+ S+ LL G P+ Sbjct: 334 DVWSIGVISYILLCGSRPF 352
>P53682:CDPK1_ORYSJ Calcium-dependent protein kinase, isoform 1 - Oryza sativa subsp.| japonica (Rice) Length = 534 Score = 44.7 bits (104), Expect = 0.002 Identities = 45/159 (28%), Positives = 70/159 (44%), Gaps = 2/159 (1%) Frame = +3 Query: 570 YKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYSS 749 Y + R+LG+G FG+ Y+ +S G + A + LK R E Q+ Sbjct: 73 YTLGRELGQGQFGKTYLCTEISTGCQY----ACKTILKSNLRCVSDIE-DVRREIQIMHH 127 Query: 750 LNGCYGIPWVH--YKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISIL 923 L+G I + Y+ Q + V+ + G L+ G I + + I+ Sbjct: 128 LSGQKNIVTIKDTYEDEQAVHIVMEL-CAGGELFSKIQKRGHYSERKAAELIKI-IVGII 185 Query: 924 EKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLA 1040 E H+ G +H D+KPENFLL + DE + ID GL+ Sbjct: 186 ETCHSHGVMHRDLKPENFLL--LDADDEFSVKAIDFGLS 222
>Q3SWY6:STK25_BOVIN Serine/threonine-protein kinase 25 - Bos taurus (Bovine)| Length = 426 Score = 44.3 bits (103), Expect = 0.003 Identities = 68/288 (23%), Positives = 112/288 (38%), Gaps = 13/288 (4%) Frame = +3 Query: 585 KLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKF-EHRNSKGCNYGPPYEWQVYSSLNGC 761 ++GKG FG+VY G + T+ VA+K + ++ E V S + Sbjct: 25 RIGKGSFGEVYKG--IDNRTKEV------VAIKIIDLEEAEDEIEDIQQEITVLSQCDSP 76 Query: 762 YGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISILEKLHAK 941 Y + + ++++ + G S D+ + + +A I E + L+ LH++ Sbjct: 77 YITRYFGSYLKSTKLWIIMEYLGGGSALDLLKP--GPLEETYIATILREILKGLDYLHSE 134 Query: 942 GFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFRGTIRY 1121 +H D+K N LL + G + L D G+A GQ D + + F GT + Sbjct: 135 RKIHRDIKAANVLLSEQGD-----VKLADFGVA--------GQLTDTQIKRNTFVGTPFW 181 Query: 1122 ASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNKSFLVCKKKMSISPDLMCC 1301 + + D+ SL T I L +G P FL+ K SP + Sbjct: 182 MAPEVIKQSAYDFKADIWSLGITAIELAKGEPPNSDLHPMRVLFLIPKN----SPPTLEG 237 Query: 1302 YCAPPFKLFLETVTN------------MKFDEEPNYPKLISLFDELIE 1409 + + PFK F+E N +K Y K S ELI+ Sbjct: 238 HHSKPFKEFVEACLNKDPRFRPTAKELLKHKFITRYTKKTSFLTELID 285
>Q03497:STE20_YEAST Serine/threonine-protein kinase STE20 - Saccharomyces cerevisiae| (Baker's yeast) Length = 939 Score = 44.3 bits (103), Expect = 0.003 Identities = 28/87 (32%), Positives = 44/87 (50%) Frame = +3 Query: 795 QGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISILEKLHAKGFVHGDVKPEN 974 +GD +V++ + G SL DV +T + + E +S LE LH+KG +H D+K +N Sbjct: 687 KGDLWVIMEYMEGGSLTDVVTHC--ILTEGQIGAVCRETLSGLEFLHSKGVLHRDIKSDN 744 Query: 975 FLLGQPGSPDEKKLFLIDLGLASKWKE 1055 LL G + L D G ++ E Sbjct: 745 ILLSMEGD-----IKLTDFGFCAQINE 766
>Q7Z8E9:STE20_MAGGR Serine/threonine-protein kinase MST20 - Magnaporthe grisea (Rice| blast fungus) (Pyricularia grisea) Length = 914 Score = 44.3 bits (103), Expect = 0.003 Identities = 36/142 (25%), Positives = 62/142 (43%) Frame = +3 Query: 798 GDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISILEKLHAKGFVHGDVKPENF 977 G+ +V++ + G SL DV MT +A + E + L+ LH+KG +H D+K +N Sbjct: 702 GELWVVMEFMEGGSLTDVVTF--NIMTEGQIASVCRETLLGLQHLHSKGVIHRDIKSDNI 759 Query: 978 LLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFRGTIRYASVHAHLGRTGS 1157 LL G+ + L D G + E + + GT + + + Sbjct: 760 LLSMEGN-----IKLTDFGFCATINEAQN--------KRTTMVGTPYWMAPEVVTRKEYG 806 Query: 1158 RRDDLESLAYTLIFLLRGRLPW 1223 R+ D+ SL I ++ G P+ Sbjct: 807 RKVDIWSLGIMAIEMIEGEPPY 828
>Q92212:STE20_CANAL Serine/threonine-protein kinase CST20 - Candida albicans (Yeast)| Length = 1228 Score = 44.3 bits (103), Expect = 0.003 Identities = 26/90 (28%), Positives = 46/90 (51%) Frame = +3 Query: 795 QGDYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISILEKLHAKGFVHGDVKPEN 974 +GD +V++ + G SL D+ MT + + E + L+ LH+KG +H D+K +N Sbjct: 1019 KGDLWVIMEYMEGGSLTDIVTH--SVMTEGQIGVVCRETLKGLKFLHSKGVIHRDIKSDN 1076 Query: 975 FLLGQPGSPDEKKLFLIDLGLASKWKETSS 1064 LL G+ + + D G ++ E +S Sbjct: 1077 ILLNMDGN-----IKITDFGFCAQINEINS 1101
>Q2ULU3:STE20_ASPOR Serine/threonine-protein kinase ste20 - Aspergillus oryzae| Length = 848 Score = 44.3 bits (103), Expect = 0.003 Identities = 58/235 (24%), Positives = 92/235 (39%), Gaps = 12/235 (5%) Frame = +3 Query: 801 DYYVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISILEKLHAKGFVHGDVKPENFL 980 D +V++ + G SL DV M+ +A + E ++ L+ LH+KG +H D+K +N L Sbjct: 636 DLWVVMEYMEGGSLTDVVTF--NIMSEGQIAAVCRETLNGLQHLHSKGVIHRDIKSDNIL 693 Query: 981 LGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFRGTIRYASVHAHLGRTGSR 1160 L G+ + L D G + Q D + + GT + + + R Sbjct: 694 LSLDGN-----IKLTDFGFCA--------QINDSHNKRNTMVGTPYWMAPEVVTRKEYGR 740 Query: 1161 RDDLESLAYTLIFLLRGRLPWQGYQGDNKSFLVCKKKMSISPDLMCCYCAPPFKLFLETV 1340 + D+ SL I ++ G P+ +L+ D P F+ FL Sbjct: 741 KVDIWSLGIMAIEMIEGEPPYLTESPLRALYLIATNGTPTIKDEQS--LTPVFRDFLHLA 798 Query: 1341 TNMKFDEEPNYPKLISLFDELIEP--------QHLRPI----RIDGALKAGQKRG 1469 +K D E K S D L P HL P+ R+ A + QK G Sbjct: 799 --LKVDPE----KRASAHDLLKHPFMSFCAPLSHLAPLVKAARLSRAQEKAQKGG 847
>P38622:RCK1_YEAST Serine/threonine-protein kinase RCK1 - Saccharomyces cerevisiae| (Baker's yeast) Length = 512 Score = 44.3 bits (103), Expect = 0.003 Identities = 62/278 (22%), Positives = 110/278 (39%), Gaps = 31/278 (11%) Frame = +3 Query: 537 PEKVQVGHSPQYKVERKLGKGGFGQVYVGRRVSGGTERTGPDAY----------EVALKF 686 PE++++ + YK+ K+G+G F +V+ + V T+ P A + LK Sbjct: 113 PEQLELHN---YKLLNKIGEGAFSRVF--KAVGINTDDQAPVAIKAIIKKGISSDAILKG 167 Query: 687 EHRNSKGCNYGPPYEWQVYS--SLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNS 860 R E ++ S N + ++ ++ YY++ + G ++D Sbjct: 168 NDRIQGSSRKKVLNEVAIHKLVSKNNPHCTKFIAFQESANYYYLVTELVTGGEIFDRIVQ 227 Query: 861 LGQTMTPSMVACIAVEAISILEKLHAKGFVHGDVKPENFLL------GQPGSPDEKKLF- 1019 L + + + + ++ +H G VH DVKPEN L G G ++ F Sbjct: 228 L-TCFSEDLARHVITQVAIAIKHMHYMGIVHRDVKPENLLFEPIPFYGLDGDMQKEDEFT 286 Query: 1020 ------------LIDLGLASKWKETSSGQHVDYDQRPDIFRGTIRYASVHAHLGRTGSRR 1163 L+D GLA K + ++ GTI Y + + S + Sbjct: 287 LGVGGGGIGLVKLMDFGLAKKLRNNTAKTPC----------GTIEYVASEVFTSKRYSMK 336 Query: 1164 DDLESLAYTLIFLLRGRLPWQGYQGDNKSFLVCKKKMS 1277 D+ S+ L LL G P+ Y+ + K+ L KK+S Sbjct: 337 VDMWSIGCVLFTLLCGYPPF--YEKNEKTLL---KKIS 369
>P54744:PKNB_MYCLE Probable serine/threonine-protein kinase pknB - Mycobacterium leprae| Length = 622 Score = 44.3 bits (103), Expect = 0.003 Identities = 37/141 (26%), Positives = 63/141 (44%) Frame = +3 Query: 807 YVLVMDILGPSLWDVWNSLGQTMTPSMVACIAVEAISILEKLHAKGFVHGDVKPENFLLG 986 Y+++ + G +L D+ ++ G M P I +A L H G +H DVKP N ++ Sbjct: 89 YIVMEYVDGATLRDIVHTDGP-MPPQQAIEIVADACQALNFSHQNGIIHRDVKPANIMIS 147 Query: 987 QPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIFRGTIRYASVHAHLGRTGSRRD 1166 + + ++D G+A +++S Q + GT +Y S G + R Sbjct: 148 ATNA-----VKVMDFGIARAIADSTS-----VTQTAAVI-GTAQYLSPEQARGDSVDARS 196 Query: 1167 DLESLAYTLIFLLRGRLPWQG 1229 D+ SL L +L G P+ G Sbjct: 197 DVYSLGCVLYEILTGEPPFIG 217
>Q6DT37:MRCKG_HUMAN Serine/threonine-protein kinase MRCK gamma - Homo sapiens (Human)| Length = 1551 Score = 44.3 bits (103), Expect = 0.003 Identities = 39/160 (24%), Positives = 66/160 (41%), Gaps = 3/160 (1%) Frame = +3 Query: 525 ASPVPEKVQVGHSPQ--YKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRN 698 ASP KV+ + +++ + +G+G FG+V V R+ G + + + + Sbjct: 54 ASPFVSKVKELRLQRDDFEILKVIGRGAFGEVTVVRQRDTG------QIFAMKMLHKWEM 107 Query: 699 SKGCNYGPPYEWQVYSSLNGCYGIPWVHYKGRQGDYYVLVMDIL-GPSLWDVWNSLGQTM 875 K E + + +HY + +Y LVMD G L + + + Sbjct: 108 LKRAETACFREERDVLVKGDSRWVTTLHYAFQDEEYLYLVMDYYAGGDLLTLLSRFEDRL 167 Query: 876 TPSMVACIAVEAISILEKLHAKGFVHGDVKPENFLLGQPG 995 P + E + + LH G+VH DVKP+N LL G Sbjct: 168 PPELAQFYLAEMVLAIHSLHQLGYVHRDVKPDNVLLDVNG 207
>P32350:KNS1_YEAST Dual specificity protein kinase KNS1 - Saccharomyces cerevisiae| (Baker's yeast) Length = 737 Score = 44.3 bits (103), Expect = 0.003 Identities = 65/249 (26%), Positives = 99/249 (39%), Gaps = 30/249 (12%) Frame = +3 Query: 555 GHSPQYKVERKLGKGGFGQV-----------YVGRRVSGGTERTGPDAYEVALKFEHRNS 701 G ++ V+ LG+G FG+V YV +V +R Y A K E R Sbjct: 308 GSGGRFVVKDLLGQGTFGKVLKCIDNKYEPNYVAVKVIRAVDR-----YREAAKTELRIL 362 Query: 702 KGC-NYGPPYEWQVYSSLNGCYGIPWVHYKGRQGDYYVLVMDILGPSLWDVWNSLGQTMT 878 + N P ++Q L C+ YK ++ LV D+ G S++D S G Sbjct: 363 QTILNNDPQGQFQCLL-LRECFD-----YK----NHICLVTDLYGRSIYDFMCSNGIARF 412 Query: 879 P-SMVACIAVEAISILEKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKE 1055 P S + IA + I + LH G +H D+KPEN L+ +K L+ + +E Sbjct: 413 PGSHIQAIARQLIRSVCFLHDLGIIHTDLKPENILICDETHIAQKLPLKTVQSLSKRRRE 472 Query: 1056 TSSGQH-----------------VDYDQRPDIFRGTIRYASVHAHLGRTGSRRDDLESLA 1184 S G+ Y+ P + T Y + LG S D+ S+A Sbjct: 473 ASKGKRKILKNPEIKIIDFGSAIFHYEYHPPVI-STRHYRAPEIVLGLGWSFPCDIWSIA 531 Query: 1185 YTLIFLLRG 1211 L+ L+ G Sbjct: 532 CVLVELVIG 540
>Q62833:GRK5_RAT G protein-coupled receptor kinase 5 - Rattus norvegicus (Rat)| Length = 590 Score = 44.3 bits (103), Expect = 0.003 Identities = 55/225 (24%), Positives = 88/225 (39%), Gaps = 5/225 (2%) Frame = +3 Query: 570 YKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYSS 749 ++ R LGKGGFG+V + + G + +K S N E Q+ Sbjct: 186 FRQYRVLGKGGFGEVCACQVRATGKMYACKRLEKKRIKKRKGESMALN-----EKQILEK 240 Query: 750 LNGCYGIPWVHYKGRQGDYYVLVMDIL--GPSLWDVWNSLGQTMTPSMVACIAVEAISIL 923 +N + + + Y D LV+ I+ G + ++N A E + L Sbjct: 241 VNSQFVVN-LAYAYETKDALCLVLTIMNGGDLKFHIYNMGNPGFEEERALFYAAEILCGL 299 Query: 924 EKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIF 1103 E LH + V+ D+KPEN LL G + + DLGLA K E D+ Sbjct: 300 EDLHRENTVYRDLKPENILLDDYG-----HIRISDLGLAVKIPE------------GDLI 342 Query: 1104 R---GTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQG 1229 R GT+ Y + + D L + ++ G+ P++G Sbjct: 343 RGRVGTVGYMAPEVLNNQRYGLSPDYWGLGCLIYEMIEGQSPFRG 387
>Q8VEB1:GRK5_MOUSE G protein-coupled receptor kinase 5 - Mus musculus (Mouse)| Length = 590 Score = 44.3 bits (103), Expect = 0.003 Identities = 55/225 (24%), Positives = 88/225 (39%), Gaps = 5/225 (2%) Frame = +3 Query: 570 YKVERKLGKGGFGQVYVGRRVSGGTERTGPDAYEVALKFEHRNSKGCNYGPPYEWQVYSS 749 ++ R LGKGGFG+V + + G + +K S N E Q+ Sbjct: 186 FRQYRVLGKGGFGEVCACQVRATGKMYACKRLEKKRIKKRKGESMALN-----EKQILEK 240 Query: 750 LNGCYGIPWVHYKGRQGDYYVLVMDIL--GPSLWDVWNSLGQTMTPSMVACIAVEAISIL 923 +N + + + Y D LV+ I+ G + ++N A E + L Sbjct: 241 VNSQFVVN-LAYAYETKDALCLVLTIMNGGDLKFHIYNMGNPGFEEERALFYAAEILCGL 299 Query: 924 EKLHAKGFVHGDVKPENFLLGQPGSPDEKKLFLIDLGLASKWKETSSGQHVDYDQRPDIF 1103 E LH + V+ D+KPEN LL G + + DLGLA K E D+ Sbjct: 300 EDLHRENTVYRDLKPENILLDDYG-----HIRISDLGLAVKIPE------------GDLI 342 Query: 1104 R---GTIRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQG 1229 R GT+ Y + + D L + ++ G+ P++G Sbjct: 343 RGRVGTVGYMAPEVLNNQRYGLSPDYWGLGCLIYEMIEGQSPFRG 387 Database: uniprot_sprot.fasta.out Posted date: Jul 19, 2007 5:58 PM Number of letters in database: 100,686,439 Number of sequences in database: 274,295 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 274295 Number of Hits to DB: 480,397,908 Number of extensions: 10988941 Number of successful extensions: 29466 Number of sequences better than 10.0: 993 Number of HSP's gapped: 29016 Number of HSP's successfully gapped: 999 Length of query: 905 Length of database: 100,686,439 Length adjustment: 122 Effective length of query: 783 Effective length of database: 67,222,449 Effective search space: 52635177567 Effective search space used: 52635177567 Neighboring words threshold: 12 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
