ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | FLbaf88j09 |
|---|---|
| Clone Library Name | barley_pub |
>Q9Y394:DHRS7_HUMAN Dehydrogenase/reductase SDR family member 7 precursor - Homo| sapiens (Human) Length = 339 Score = 176 bits (446), Expect = 2e-43 Identities = 107/302 (35%), Positives = 170/302 (56%), Gaps = 15/302 (4%) Frame = +1 Query: 106 KFVTADGDFTLLSC---GRPRRDKVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARN 276 +F+ ADGD TLL GR ++ VVW+TGAS GIGE L+ Q + LG L+LSAR Sbjct: 24 RFLRADGDLTLLWAEWQGRRPEWELTDMVVWVTGASSGIGEELAYQLSKLGVSLVLSARR 83 Query: 277 KEELERVKHNIMSKH--PDSKVEVLPMDLS---SDEKSLKEVVHSAESLFSSAGIDYMMH 441 ELERVK + + + VLP+DL+ S E + K V+ ID +++ Sbjct: 84 VHELERVKRRCLENGNLKEKDILVLPLDLTDTGSHEAATKAVLQEF------GRIDILVN 137 Query: 442 NAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVP 621 N + + ++ + + + ++N GT++LT+ + P M++R G V ++S G + Sbjct: 138 NGGMSQ-RSLCMDTSLDVYRKLIELNYLGTVSLTKCVLPHMIERKQGKIVTVNSILGIIS 196 Query: 622 TPGQALYSASKHALNGYFASLRSELCT-KGIKVTVVCPGPIETP----ESSGATSSSQRH 786 P Y ASKHAL G+F LR+EL T GI V+ +CPGP+++ +G + + + Sbjct: 197 VPLSIGYCASKHALRGFFNGLRTELATYPGIIVSNICPGPVQSNIVENSLAGEVTKTIGN 256 Query: 787 SSEK--RVSVERCAELTIVAATHGLKEAWISYQPVLAVMYVVQYMPTIGCWLMDKVGAKR 960 + ++ +++ RC L +++ + LKE WIS QP L V Y+ QYMPT W+ +K+G KR Sbjct: 257 NGDQSHKMTTSRCVRLMLISMANDLKEVWISEQPFLLVTYLWQYMPTWAWWITNKMGKKR 316 Query: 961 VD 966 ++ Sbjct: 317 IE 318
>Q9CXR1:DHRS7_MOUSE Dehydrogenase/reductase SDR family member 7 precursor - Mus| musculus (Mouse) Length = 338 Score = 165 bits (418), Expect = 4e-40 Identities = 112/302 (37%), Positives = 162/302 (53%), Gaps = 16/302 (5%) Frame = +1 Query: 106 KFVTADGDFTLLSC---GRPRRDKVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARN 276 +F+ AD D TLL GR ++ VVW+TGAS GIGE L+ Q + LG L+LSAR Sbjct: 24 RFLRADADLTLLWAEWQGRRPEWELTDMVVWVTGASSGIGEELAFQLSKLGVSLVLSARR 83 Query: 277 KEELERVKHNIMSKH--PDSKVEVLPMDL---SSDEKSLKEVVHSAESLFSSAGIDYMMH 441 +ELERVK + + + VLP+DL SS E + K V L ID +++ Sbjct: 84 AQELERVKRRCLENGNLKEKDILVLPLDLTDTSSHEAATKAV------LQEFGKIDILVN 137 Query: 442 NAAFERPKRGALEETE-EGLKATFKVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKV 618 N R +R + ET + K +N GT++LT+ + P M++R G V ++S AG Sbjct: 138 NGG--RSQRSLVLETNLDVFKELINLNYIGTVSLTKCVLPHMIERKQGKIVTVNSIAGIA 195 Query: 619 PTPGQALYSASKHALNGYFASLRSELCT-KGIKVTVVCPGPIETPESSGA----TSSSQR 783 + Y ASKHAL G+F +L SEL GI V PGP+++ A + S R Sbjct: 196 SVSLSSGYCASKHALRGFFNALHSELGQYPGITFCNVYPGPVQSDIVKNAFTEEVTKSMR 255 Query: 784 HSSEK--RVSVERCAELTIVAATHGLKEAWISYQPVLAVMYVVQYMPTIGCWLMDKVGAK 957 ++ ++ ++ RC L +++ + LKE WIS PVL Y+ QYMPT WL K+G + Sbjct: 256 NNIDQSYKMPTSRCVRLMLISMANDLKEVWISDHPVLLGAYIWQYMPTWAAWLNCKLGKE 315 Query: 958 RV 963 R+ Sbjct: 316 RI 317
>P54554:YQJQ_BACSU Uncharacterized oxidoreductase yqjQ - Bacillus subtilis| Length = 259 Score = 131 bits (330), Expect = 6e-30 Identities = 77/193 (39%), Positives = 118/193 (61%) Frame = +1 Query: 169 VDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLP 348 + GK +WITGAS G+GE ++ A+ GA ++LSAR ++ L +K I + + E+ P Sbjct: 4 IAGKRIWITGASGGLGERIAYLCAAEGAHVLLSARREDRLIEIKRKITEEW-SGQCEIFP 62 Query: 349 MDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFG 528 +D+ L+++ + + S ID +++NA F + L+ T + +KA F VNVFG Sbjct: 63 LDVGR----LEDIARVRDQIGS---IDVLINNAGFGIFET-VLDSTLDDMKAMFDVNVFG 114 Query: 529 TITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKG 708 I T+ + P ML++ GH + ++S AGK+ TP +LYSA+KHA+ GY +LR EL G Sbjct: 115 LIACTKAVLPQMLEQKKGHIINIASQAGKIATPKSSLYSATKHAVLGYSNALRMELSGTG 174 Query: 709 IKVTVVCPGPIET 747 I VT V PGPI+T Sbjct: 175 IYVTTVNPGPIQT 187
>Q05016:YM71_YEAST Uncharacterized oxidoreductase YMR226C - Saccharomyces cerevisiae| (Baker's yeast) Length = 267 Score = 103 bits (256), Expect = 2e-21 Identities = 69/206 (33%), Positives = 110/206 (53%), Gaps = 3/206 (1%) Frame = +1 Query: 139 LSCGRPRRDKVDGKVVWITGASRGIGEVLSMQF--ASLG-AKLILSARNKEELERVKHNI 309 +S GR +++ K V ITGAS GIG+ ++++ AS G KLIL+AR E+LE +K I Sbjct: 1 MSQGRKAAERLAKKTVLITGASAGIGKATALEYLEASNGDMKLILAARRLEKLEELKKTI 60 Query: 310 MSKHPDSKVEVLPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETE 489 + P++KV V +D++ EK +K + + F ID +++NA + Sbjct: 61 DQEFPNAKVHVAQLDITQAEK-IKPFIENLPQEFKD--IDILVNNAGKALGSDRVGQIAT 117 Query: 490 EGLKATFKVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNG 669 E ++ F NV I +T+ + P + G V + S AG+ P ++Y ASK A+ Sbjct: 118 EDIQDVFDTNVTALINITQAVLPIFQAKNSGDIVNLGSIAGRDAYPTGSIYCASKFAVGA 177 Query: 670 YFASLRSELCTKGIKVTVVCPGPIET 747 + SLR EL I+V ++ PG +ET Sbjct: 178 FTDSLRKELINTKIRVILIAPGLVET 203
>Q5NVG2:DHRS8_PONPY Dehydrogenase/reductase SDR family member 8 precursor - Pongo| pygmaeus (Orangutan) Length = 300 Score = 94.4 bits (233), Expect = 1e-18 Identities = 67/206 (32%), Positives = 97/206 (47%), Gaps = 9/206 (4%) Frame = +1 Query: 157 RRDKVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKV 336 RR V G++V ITGA GIG + + +FA L +KL+L NK LE K +KV Sbjct: 30 RRKSVTGEIVLITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKC--KGLGAKV 87 Query: 337 EVLPMDLSSDE------KSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGL 498 +D S+ E K +K + L ++AG+ Y A + P+ + Sbjct: 88 HTFVVDCSNREDIYSAAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQ----------I 137 Query: 499 KATFKVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFA 678 + TF+VNV T+ P M+ GH V ++SAAG V P Y +SK A G+ Sbjct: 138 EKTFEVNVLAHFWTTKAFLPAMMKNNHGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHK 197 Query: 679 SLRSELCT---KGIKVTVVCPGPIET 747 +L EL G+K T +CP + T Sbjct: 198 TLTDELAALQITGVKTTCLCPNFVNT 223
>Q8NBQ5:DHRS8_HUMAN Dehydrogenase/reductase SDR family member 8 precursor - Homo| sapiens (Human) Length = 300 Score = 93.2 bits (230), Expect = 2e-18 Identities = 67/206 (32%), Positives = 96/206 (46%), Gaps = 9/206 (4%) Frame = +1 Query: 157 RRDKVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKV 336 RR V G++V ITGA GIG + + +FA L +KL+L NK LE K +KV Sbjct: 30 RRKSVTGEIVLITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKC--KGLGAKV 87 Query: 337 EVLPMDLSSDE------KSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGL 498 +D S+ E K +K + L ++AG+ Y A + P+ + Sbjct: 88 HTFVVDCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQ----------I 137 Query: 499 KATFKVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFA 678 + TF+VNV T+ P M GH V ++SAAG V P Y +SK A G+ Sbjct: 138 EKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHK 197 Query: 679 SLRSELCT---KGIKVTVVCPGPIET 747 +L EL G+K T +CP + T Sbjct: 198 TLTDELAALQITGVKTTCLCPNFVNT 223
>Q9X248:FABG_THEMA 3-oxoacyl-[acyl-carrier-protein] reductase - Thermotoga maritima| Length = 246 Score = 92.8 bits (229), Expect = 3e-18 Identities = 63/195 (32%), Positives = 101/195 (51%) Frame = +1 Query: 166 KVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVL 345 +++GKV ITGA+ GIG+ ++ FA GA +I +KE L+ + ++ KV+ Sbjct: 2 RLEGKVCLITGAASGIGKATTLLFAQEGATVIAGDISKENLDSLVKE--AEGLPGKVDPY 59 Query: 346 PMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVF 525 ++++ D +KEVV + ID +++NA R + EE A VN+ Sbjct: 60 VLNVT-DRDQIKEVVEKVVQKYGR--IDVLVNNAGITRDAL-LVRMKEEDWDAVINVNLK 115 Query: 526 GTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTK 705 G +T+++ P+M+ + G V +SS G PGQ Y+ASK + G + EL + Sbjct: 116 GVFNVTQMVVPYMIKQRNGSIVNVSSVVGIYGNPGQTNYAASKAGVIGMTKTWAKELAGR 175 Query: 706 GIKVTVVCPGPIETP 750 I+V V PG IETP Sbjct: 176 NIRVNAVAPGFIETP 190
>Q8SPU8:DHRS4_BOVIN Dehydrogenase/reductase SDR family member 4 - Bos taurus (Bovine)| Length = 260 Score = 91.7 bits (226), Expect = 7e-18 Identities = 64/221 (28%), Positives = 102/221 (46%) Frame = +1 Query: 136 LLSCGRPRRDKVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMS 315 + SCG RR+ +D KV +T ++ GIG ++ + A GA +++S+R ++ ++R + Sbjct: 1 MASCGMARRNPLDNKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDRAVATLKG 60 Query: 316 KHPDSKVEVLPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEG 495 + V + + D + L A ++ G+D ++ NAA ++ EE Sbjct: 61 EGLSVTGTVCHVGKAEDRERLV-----ATAVKLHGGVDILISNAAVSPFFGSLMDVPEEV 115 Query: 496 LKATFKVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYF 675 VNV T LT+ + P M RG G V++SS A P P Y+ SK AL G Sbjct: 116 WDKILDVNVKATALLTKAVVPEMAKRGGGSIVIVSSIAAYSPFPSLGPYNVSKTALLGLT 175 Query: 676 ASLRSELCTKGIKVTVVCPGPIETPESSGATSSSQRHSSEK 798 +L EL ++V + PG I T S R S K Sbjct: 176 KNLALELAESNVRVNCLAPGLIRTSFSRVLWEDPARQESIK 216
>P71564:Y945_MYCTU Uncharacterized oxidoreductase Rv0945/MT0971 - Mycobacterium| tuberculosis Length = 253 Score = 91.3 bits (225), Expect = 9e-18 Identities = 63/201 (31%), Positives = 101/201 (50%), Gaps = 4/201 (1%) Frame = +1 Query: 184 VWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSS 363 + ITGAS G+G ++ FA+ G L L AR + L +K + ++PD K+ V +D++ Sbjct: 10 ILITGASSGLGAGMARSFAAQGRDLALCARRTDRLTELKAELSQRYPDIKIAVAELDVND 69 Query: 364 DEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKR---GALEETEEGLKATFKVNVFGTI 534 E+ K ++ + GID ++ NA + R G L KAT + N+ + Sbjct: 70 HERVPKVFAELSDEI---GGIDRVIVNAGIGKGARLGSGKLWAN----KATIETNLVAAL 122 Query: 535 TLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPG-QALYSASKHALNGYFASLRSELCTKGI 711 RG GH V++SS G PG +A Y+ASK + SLR+E + I Sbjct: 123 VQIETALDMFNQRGSGHLVLISSVLGVKGVPGVKAAYAASKAGVRSLGESLRAEYAQRPI 182 Query: 712 KVTVVCPGPIETPESSGATSS 774 +VTV+ PG IE+ ++ + S+ Sbjct: 183 RVTVLEPGYIESEMTAKSAST 203
>O67610:FABG_AQUAE 3-oxoacyl-[acyl-carrier-protein] reductase - Aquifex aeolicus| Length = 248 Score = 90.9 bits (224), Expect = 1e-17 Identities = 67/200 (33%), Positives = 105/200 (52%), Gaps = 6/200 (3%) Frame = +1 Query: 166 KVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVL 345 K+ GKV +TG++RGIG ++ + AS G+ +I++ + E + V I +K+ K + Sbjct: 4 KLQGKVSLVTGSTRGIGRAIAEKLASAGSTVIITGTSGERAKAVAEEIANKY-GVKAHGV 62 Query: 346 PMDLSSDE---KSLKEVVHSAESLFSSAGIDYMMHNAAFERPK---RGALEETEEGLKAT 507 M+L S+E K+ +E+ + + GID +++NA R K R +L + EE LK Sbjct: 63 EMNLLSEESINKAFEEIYNLVD------GIDILVNNAGITRDKLFLRMSLLDWEEVLK-- 114 Query: 508 FKVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLR 687 VN+ GT +T+ M+ + G V +SS G GQ YS +K L G+ SL Sbjct: 115 --VNLTGTFLVTQNSLRKMIKQRWGRIVNISSVVGFTGNVGQVNYSTTKAGLIGFTKSLA 172 Query: 688 SELCTKGIKVTVVCPGPIET 747 EL + + V V PG IET Sbjct: 173 KELAPRNVLVNAVAPGFIET 192
>Q5RCF8:DHRS4_PONPY Dehydrogenase/reductase SDR family member 4 - Pongo pygmaeus| (Orangutan) Length = 260 Score = 90.9 bits (224), Expect = 1e-17 Identities = 63/221 (28%), Positives = 107/221 (48%) Frame = +1 Query: 136 LLSCGRPRRDKVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMS 315 + S G RRD + KV +T ++ GIG ++ + A GA +++S+R ++ +++ + Sbjct: 1 MASSGMTRRDPLANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQG 60 Query: 316 KHPDSKVEVLPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEG 495 + V + + D + L A ++ GID ++ NAA ++ TEE Sbjct: 61 EGLSVTGTVCHVGKAEDRERLV-----ATAVKLHGGIDILVSNAAVNPFFGSLMDVTEEV 115 Query: 496 LKATFKVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYF 675 T +NV +T+ + P M RG G V++SS A P+PG + Y+ SK AL G Sbjct: 116 WDKTLDINVKAPALMTKAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLT 175 Query: 676 ASLRSELCTKGIKVTVVCPGPIETPESSGATSSSQRHSSEK 798 +L EL + I+V + PG I+T S ++ S K Sbjct: 176 KTLAIELAPRNIRVNCLAPGLIKTSFSRMLWMDKEKEESMK 216
>Q9BTZ2:DHRS4_HUMAN Dehydrogenase/reductase SDR family member 4 - Homo sapiens (Human)| Length = 260 Score = 90.9 bits (224), Expect = 1e-17 Identities = 63/221 (28%), Positives = 107/221 (48%) Frame = +1 Query: 136 LLSCGRPRRDKVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMS 315 + S G RRD + KV +T ++ GIG ++ + A GA +++S+R ++ +++ + Sbjct: 1 MASSGMTRRDPLANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQG 60 Query: 316 KHPDSKVEVLPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEG 495 + V + + D + L A ++ GID ++ NAA ++ TEE Sbjct: 61 EGLSVTGTVCHVGKAEDRERLV-----ATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEV 115 Query: 496 LKATFKVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYF 675 T +NV +T+ + P M RG G V++SS A P+PG + Y+ SK AL G Sbjct: 116 WDKTLDINVKAPALMTKAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLT 175 Query: 676 ASLRSELCTKGIKVTVVCPGPIETPESSGATSSSQRHSSEK 798 +L EL + I+V + PG I+T S ++ S K Sbjct: 176 KTLAIELAPRNIRVNCLAPGLIKTSFSRMLWMDKEKEESMK 216
>P37694:HETN_ANASP Ketoacyl reductase hetN - Anabaena sp. (strain PCC 7120)| Length = 287 Score = 89.7 bits (221), Expect = 3e-17 Identities = 60/187 (32%), Positives = 99/187 (52%) Frame = +1 Query: 175 GKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMD 354 GK V +TGASRG+G ++ A A ++ +R++ L + + + K K +P D Sbjct: 6 GKTVLLTGASRGLGVYIARALAKEQATVVCVSRSQSGLAQTCNAV--KAAGGKAIAIPFD 63 Query: 355 LSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTI 534 + + + L +V A+ + ID +++NA E A E +++ F N+ + Sbjct: 64 VRNTSQ-LSALVQQAQDIVGP--IDVLINNAGIEINGTFANYSLAE-IQSIFNTNLLAAM 119 Query: 535 TLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 714 LTRLL P M++RG G V ++S AGK ++YSASK L + ++R EL G+ Sbjct: 120 ELTRLLLPSMMERGSGRIVNIASLAGKKGVAFNSVYSASKAGLIMWTDAMRQELVGTGVN 179 Query: 715 VTVVCPG 735 ++VVCPG Sbjct: 180 ISVVCPG 186
>P0A2D1:UCPA_SALTY Oxidoreductase ucpA - Salmonella typhimurium| Length = 263 Score = 89.0 bits (219), Expect = 4e-17 Identities = 67/212 (31%), Positives = 105/212 (49%), Gaps = 2/212 (0%) Frame = +1 Query: 166 KVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSK-HPDSKVEV 342 K+ GK ITGAS+GIGE ++ FA GA LIL + +E+E++ + + H + V+ Sbjct: 3 KLTGKTALITGASQGIGEGIARVFARHGANLILLDIS-DEIEKLADELGGRGHRCTAVKA 61 Query: 343 LPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNV 522 D +S + ++ A + + ID +++NA R L+ +EE +N+ Sbjct: 62 DVRDFASVQAAV------ARAKETEGRIDILVNNAGVCR-LGNFLDMSEEDRDFHIDINI 114 Query: 523 FGTITLTRLLAPFMLDRGMGHFVVMSSAAGK-VPTPGQALYSASKHALNGYFASLRSELC 699 G +T+ + P M+ R G V+MSS G V PG+ Y+ SK A+ G SL E Sbjct: 115 KGVWNVTKAVLPEMIKRKDGRIVMMSSVTGDMVADPGETAYALSKAAIVGLTKSLAVEYA 174 Query: 700 TKGIKVTVVCPGPIETPESSGATSSSQRHSSE 795 GI+V +CPG + TP + S E Sbjct: 175 QSGIRVNAICPGYVRTPMAESIARQSNPDDPE 206
>P0A2D2:UCPA_SALTI Oxidoreductase ucpA - Salmonella typhi| Length = 263 Score = 89.0 bits (219), Expect = 4e-17 Identities = 67/212 (31%), Positives = 105/212 (49%), Gaps = 2/212 (0%) Frame = +1 Query: 166 KVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSK-HPDSKVEV 342 K+ GK ITGAS+GIGE ++ FA GA LIL + +E+E++ + + H + V+ Sbjct: 3 KLTGKTALITGASQGIGEGIARVFARHGANLILLDIS-DEIEKLADELGGRGHRCTAVKA 61 Query: 343 LPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNV 522 D +S + ++ A + + ID +++NA R L+ +EE +N+ Sbjct: 62 DVRDFASVQAAV------ARAKETEGRIDILVNNAGVCR-LGNFLDMSEEDRDFHIDINI 114 Query: 523 FGTITLTRLLAPFMLDRGMGHFVVMSSAAGK-VPTPGQALYSASKHALNGYFASLRSELC 699 G +T+ + P M+ R G V+MSS G V PG+ Y+ SK A+ G SL E Sbjct: 115 KGVWNVTKAVLPEMIKRKDGRIVMMSSVTGDMVADPGETAYALSKAAIVGLTKSLAVEYA 174 Query: 700 TKGIKVTVVCPGPIETPESSGATSSSQRHSSE 795 GI+V +CPG + TP + S E Sbjct: 175 QSGIRVNAICPGYVRTPMAESIARQSNPDDPE 206
>Q4JK73:DHRS8_MACFA Dehydrogenase/reductase SDR family member 8 precursor - Macaca| fascicularis (Crab eating macaque) (Cynomolgus monkey) Length = 300 Score = 88.2 bits (217), Expect = 7e-17 Identities = 63/206 (30%), Positives = 96/206 (46%), Gaps = 9/206 (4%) Frame = +1 Query: 157 RRDKVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKV 336 RR V G++V ITGA GIG + + +FA L +KL+L NK LE K +KV Sbjct: 30 RRKSVAGEIVLITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKC--KGLGAKV 87 Query: 337 EVLPMDLSSDE------KSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGL 498 +D S+ E K +K + L ++AG+ Y A + + + Sbjct: 88 YTFVVDCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQ----------DAQI 137 Query: 499 KATFKVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFA 678 + TF+VN+ T+ P M+ GH V ++SAAG + P Y +SK + G+ Sbjct: 138 EKTFEVNILAHFWTTKAFLPAMMKNNHGHVVTVASAAGHISVPFLLAYCSSKFSAVGFHK 197 Query: 679 SLRSELCT---KGIKVTVVCPGPIET 747 +L EL G+K T +CP + T Sbjct: 198 ALTDELAALQITGVKTTCLCPNFVNT 223
>P39071:DHBA_BACSU 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase - Bacillus subtilis| Length = 261 Score = 87.4 bits (215), Expect = 1e-16 Identities = 62/194 (31%), Positives = 97/194 (50%), Gaps = 1/194 (0%) Frame = +1 Query: 169 VDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLP 348 ++GK+ +ITGA++GIGE ++ AS GA + N E+LE+V ++ K E P Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSL--KAEARHAEAFP 63 Query: 349 MDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEE-TEEGLKATFKVNVF 525 D+ D ++ E+ E ID +++ A RP G + ++E +ATF VN Sbjct: 64 ADVR-DSAAIDEITARIER--EMGPIDILVNVAGVLRP--GLIHSLSDEEWEATFSVNST 118 Query: 526 GTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTK 705 G +R ++ +M+DR G V + S VP A Y++SK A + L EL Sbjct: 119 GVFNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEY 178 Query: 706 GIKVTVVCPGPIET 747 I+ +V PG ET Sbjct: 179 NIRCNIVSPGSTET 192
>P66780:Y1570_MYCBO Uncharacterized oxidoreductase Mb1570 - Mycobacterium bovis| Length = 341 Score = 86.3 bits (212), Expect = 3e-16 Identities = 67/211 (31%), Positives = 100/211 (47%), Gaps = 4/211 (1%) Frame = +1 Query: 148 GRPRRDKVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMS-KHP 324 GR D V GKVV ITG S GIG + + A G ++L AR E LE V ++I + + Sbjct: 44 GRNLNDAVKGKVVLITGGSSGIGAAAAKKIAEAGGTVVLVARTLENLENVANDIRAIRGN 103 Query: 325 DSKVEVLPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGL-- 498 V P DLS + V + + L G+D +++NA R R +LE + + + Sbjct: 104 GGTAHVYPCDLSDMDAI---AVMADQVLGDLGGVDILINNAG--RSIRRSLELSYDRIHD 158 Query: 499 -KATFKVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYF 675 + T ++N G + L P M +R GH V +SS + P Y ASK AL+ Sbjct: 159 YQRTMQLNYLGAVQLILKFIPGMRERHFGHIVNVSSVGVQTRAPRFGAYIASKAALDSLC 218 Query: 676 ASLRSELCTKGIKVTVVCPGPIETPESSGAT 768 +L++E ++ T V + TP S T Sbjct: 219 DALQAETVHDNVRFTTVHMALVRTPMISPTT 249
>P66779:Y1543_MYCTU Uncharacterized oxidoreductase Rv1543/MT1595 - Mycobacterium| tuberculosis Length = 341 Score = 86.3 bits (212), Expect = 3e-16 Identities = 67/211 (31%), Positives = 100/211 (47%), Gaps = 4/211 (1%) Frame = +1 Query: 148 GRPRRDKVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMS-KHP 324 GR D V GKVV ITG S GIG + + A G ++L AR E LE V ++I + + Sbjct: 44 GRNLNDAVKGKVVLITGGSSGIGAAAAKKIAEAGGTVVLVARTLENLENVANDIRAIRGN 103 Query: 325 DSKVEVLPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGL-- 498 V P DLS + V + + L G+D +++NA R R +LE + + + Sbjct: 104 GGTAHVYPCDLSDMDAI---AVMADQVLGDLGGVDILINNAG--RSIRRSLELSYDRIHD 158 Query: 499 -KATFKVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYF 675 + T ++N G + L P M +R GH V +SS + P Y ASK AL+ Sbjct: 159 YQRTMQLNYLGAVQLILKFIPGMRERHFGHIVNVSSVGVQTRAPRFGAYIASKAALDSLC 218 Query: 676 ASLRSELCTKGIKVTVVCPGPIETPESSGAT 768 +L++E ++ T V + TP S T Sbjct: 219 DALQAETVHDNVRFTTVHMALVRTPMISPTT 249
>Q8WNV7:DHRS4_PIG Dehydrogenase/reductase SDR family member 4 - Sus scrofa (Pig)| Length = 260 Score = 86.3 bits (212), Expect = 3e-16 Identities = 58/204 (28%), Positives = 99/204 (48%) Frame = +1 Query: 136 LLSCGRPRRDKVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMS 315 + S G RR ++ KV +T ++ GIG ++ + A GA +++S+R +E ++R + Sbjct: 1 MASTGVERRKPLENKVALVTASTDGIGLAIARRLAQDGAHVVVSSRKQENVDRTVATLQG 60 Query: 316 KHPDSKVEVLPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEG 495 + V + + D + L A ++ G+D ++ NAA ++ TEE Sbjct: 61 EGLSVTGTVCHVGKAEDRERLV-----AMAVNLHGGVDILVSNAAVNPFFGNIIDATEEV 115 Query: 496 LKATFKVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYF 675 VNV T+ +T+ + P M RG G +++SS P P Y+ SK AL G Sbjct: 116 WDKILHVNVKATVLMTKAVVPEMEKRGGGSVLIVSSVGAYHPFPNLGPYNVSKTALLGLT 175 Query: 676 ASLRSELCTKGIKVTVVCPGPIET 747 +L EL + I+V + PG I+T Sbjct: 176 KNLAVELAPRNIRVNCLAPGLIKT 199
>Q9EQ06:DHRS8_MOUSE Dehydrogenase/reductase SDR family member 8 precursor - Mus| musculus (Mouse) Length = 298 Score = 85.9 bits (211), Expect = 4e-16 Identities = 60/204 (29%), Positives = 93/204 (45%), Gaps = 7/204 (3%) Frame = +1 Query: 157 RRDKVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKV 336 ++ V G++V ITGA GIG + + +FA L KL+L NK +E + Sbjct: 30 KKKSVAGEIVLITGAGHGIGRLTAYEFAKLNTKLVLWDINKNGIEETAAKCRKLGAQAHP 89 Query: 337 EVLPM----DLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKA 504 V+ ++ S K +KE V L ++AG+ Y A + P+ ++ Sbjct: 90 FVVDCSQREEIYSAAKKVKEEVGDVSILVNNAGVVYTADLFATQDPQ----------IEK 139 Query: 505 TFKVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASL 684 TF+VNV T+ P M+ GH V ++SAAG P Y +SK A G+ +L Sbjct: 140 TFEVNVLAHFWTTKAFLPVMMKNNHGHIVTVASAAGHTVVPFLLAYCSSKFAAVGFHRAL 199 Query: 685 RSELCT---KGIKVTVVCPGPIET 747 EL G++ + +CP I T Sbjct: 200 TDELAALGRTGVRTSCLCPNFINT 223
>P28845:DHI1_HUMAN Corticosteroid 11-beta-dehydrogenase isozyme 1 - Homo sapiens| (Human) Length = 292 Score = 85.9 bits (211), Expect = 4e-16 Identities = 64/207 (30%), Positives = 103/207 (49%), Gaps = 2/207 (0%) Frame = +1 Query: 157 RRDKVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKV 336 R + + GK V +TGAS+GIG ++ A +GA ++++AR+KE L++V + + S Sbjct: 28 RPEMLQGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAH 87 Query: 337 EVLPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKV 516 + D ++ V A L G+D ++ N + ++ + +V Sbjct: 88 YIA--GTMEDMTFAEQFVAQAGKLMG--GLDMLILNH-ITNTSLNLFHDDIHHVRKSMEV 142 Query: 517 NVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSEL 696 N + LT P ML + G VV+SS AGKV P A YSASK AL+G+F+S+R E Sbjct: 143 NFLSYVVLTVAALP-MLKQSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEY 201 Query: 697 CTK--GIKVTVVCPGPIETPESSGATS 771 + +T+ G I+T + A S Sbjct: 202 SVSRVNVSITLCVLGLIDTETAMKAVS 228
>Q6AYS8:DHRS8_RAT Dehydrogenase/reductase SDR family member 8 precursor - Rattus| norvegicus (Rat) Length = 298 Score = 85.5 bits (210), Expect = 5e-16 Identities = 63/207 (30%), Positives = 97/207 (46%), Gaps = 10/207 (4%) Frame = +1 Query: 157 RRDKVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKV 336 ++ V G++V ITGA GIG + + +FA L KL+L NK +E + ++V Sbjct: 30 KKKSVAGEIVLITGAGHGIGRLTAYEFAKLNTKLVLWDINKNGIEETAAKC--RKLGAQV 87 Query: 337 EVLPMDLSSDE------KSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGL 498 +D S E + +KE V L ++AG+ Y A + P+ + Sbjct: 88 HPFVVDCSQREEIYSAVRKVKEEVGDVSILVNNAGVVYTADLFATQDPQ----------I 137 Query: 499 KATFKVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFA 678 + TF+VNV T+ P M+ GH V ++SAAG P Y +SK A G+ Sbjct: 138 EKTFEVNVLAHFWTTKAFLPAMMKNNHGHVVTVASAAGHTVVPFLLAYCSSKFAAVGFHR 197 Query: 679 SLRSEL----CTKGIKVTVVCPGPIET 747 +L EL CT G++ + +CP I T Sbjct: 198 ALTDELAALGCT-GVRTSCLCPNFINT 223
>Q8VID1:DHRS4_RAT Dehydrogenase/reductase SDR family member 4 - Rattus norvegicus| (Rat) Length = 260 Score = 85.5 bits (210), Expect = 5e-16 Identities = 59/208 (28%), Positives = 101/208 (48%) Frame = +1 Query: 136 LLSCGRPRRDKVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMS 315 + S G R++ + KV +T ++ GIG ++ + A GA +++S+R ++ ++R + Sbjct: 1 MASSGLTRQNPLANKVALVTASTDGIGLAIARRLAEDGAHVVISSRKQQNVDRAVATLQG 60 Query: 316 KHPDSKVEVLPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEG 495 + V + + D + L + +L GID ++ NAA ++ TEE Sbjct: 61 EGLSVTGVVCHVGKAEDREKLVNM-----ALKLHQGIDILVSNAAVNPFFGNLMDVTEEV 115 Query: 496 LKATFKVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYF 675 +NV + + + + P M RG G V++SS AG V P Y+ SK AL G Sbjct: 116 WNKVLSINVTASAMMIKAVVPAMEKRGGGSVVIVSSVAGFVLFPSLGPYNVSKTALLGLT 175 Query: 676 ASLRSELCTKGIKVTVVCPGPIETPESS 759 + +EL K I+V + PG I+T SS Sbjct: 176 KNFAAELAPKNIRVNCLAPGLIKTHFSS 203
>P0AFP4:YBBO_ECOLI Uncharacterized oxidoreductase ybbO - Escherichia coli| Length = 269 Score = 85.1 bits (209), Expect = 6e-16 Identities = 75/263 (28%), Positives = 120/263 (45%), Gaps = 7/263 (2%) Frame = +1 Query: 166 KVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVL 345 KV K V ITG S GIG +++ G ++ R +++ER+ N M + Sbjct: 12 KVMQKSVLITGCSSGIGLESALELKRQGFHVLAGCRKPDDVERM--NSMG------FTGV 63 Query: 346 PMDLSSDE---KSLKEVVHSAES----LFSSAGIDYMMHNAAFERPKRGALEETEEGLKA 504 +DL S E ++ EV+ ++ +F++AG + R + ++ Sbjct: 64 LIDLDSPESVDRAADEVIALTDNCLYGIFNNAGFGMYGPLSTISRAQ----------MEQ 113 Query: 505 TFKVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASL 684 F N FG LT L P ML G G V+ SS G + TPG+ Y+ASK+AL + +L Sbjct: 114 QFSANFFGAHQLTMRLLPAMLPHGEGRIVMTSSVMGLISTPGRGAYAASKYALEAWSDAL 173 Query: 685 RSELCTKGIKVTVVCPGPIETPESSGATSSSQRHSSEKRVSVERCAELTIVAATHGLKEA 864 R EL GIKV+++ PGPI T + + +Q + + L A ++ A Sbjct: 174 RMELRHSGIKVSLIEPGPIRT-RFTDNVNQTQSDKPVENPGIAARFTLGPEAVVDKVRHA 232 Query: 865 WISYQPVLAVMYVVQYMPTIGCW 933 +IS +P + +Y T+ W Sbjct: 233 FISEKPKM------RYPVTLVTW 249
>P0AFP5:YBBO_ECOL6 Uncharacterized oxidoreductase ybbO - Escherichia coli O6| Length = 269 Score = 85.1 bits (209), Expect = 6e-16 Identities = 75/263 (28%), Positives = 120/263 (45%), Gaps = 7/263 (2%) Frame = +1 Query: 166 KVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVL 345 KV K V ITG S GIG +++ G ++ R +++ER+ N M + Sbjct: 12 KVMQKSVLITGCSSGIGLESALELKRQGFHVLAGCRKPDDVERM--NSMG------FTGV 63 Query: 346 PMDLSSDE---KSLKEVVHSAES----LFSSAGIDYMMHNAAFERPKRGALEETEEGLKA 504 +DL S E ++ EV+ ++ +F++AG + R + ++ Sbjct: 64 LIDLDSPESVDRAADEVIALTDNCLYGIFNNAGFGMYGPLSTISRAQ----------MEQ 113 Query: 505 TFKVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASL 684 F N FG LT L P ML G G V+ SS G + TPG+ Y+ASK+AL + +L Sbjct: 114 QFSANFFGAHQLTMRLLPAMLPHGEGRIVMTSSVMGLISTPGRGAYAASKYALEAWSDAL 173 Query: 685 RSELCTKGIKVTVVCPGPIETPESSGATSSSQRHSSEKRVSVERCAELTIVAATHGLKEA 864 R EL GIKV+++ PGPI T + + +Q + + L A ++ A Sbjct: 174 RMELRHSGIKVSLIEPGPIRT-RFTDNVNQTQSDKPVENPGIAARFTLGPEAVVDKVRHA 232 Query: 865 WISYQPVLAVMYVVQYMPTIGCW 933 +IS +P + +Y T+ W Sbjct: 233 FISEKPKM------RYPVTLVTW 249
>Q99LB2:DHRS4_MOUSE Dehydrogenase/reductase SDR family member 4 - Mus musculus (Mouse)| Length = 260 Score = 84.7 bits (208), Expect = 8e-16 Identities = 59/208 (28%), Positives = 98/208 (47%) Frame = +1 Query: 136 LLSCGRPRRDKVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMS 315 + S G RR+ + KV +T ++ GIG ++ + A GA +++S+R ++ ++R + Sbjct: 1 MASSGLTRRNPLSNKVALVTASTDGIGFAIARRLAEDGAHVVVSSRKQQNVDRAVATLQG 60 Query: 316 KHPDSKVEVLPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEG 495 + V + + D + L +L GID ++ NAA ++ TEE Sbjct: 61 EGLSVTGIVCHVGKAEDREKL-----ITTALKRHRGIDILVSNAAVNPFFGNLMDVTEEV 115 Query: 496 LKATFKVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYF 675 +NV T + + + P M RG G V++ S AG P Y+ SK AL G Sbjct: 116 WDKVLSINVTATAMMIKAVVPEMEKRGGGSVVIVGSVAGFTRFPSLGPYNVSKTALLGLT 175 Query: 676 ASLRSELCTKGIKVTVVCPGPIETPESS 759 + +EL K I+V + PG I+T SS Sbjct: 176 KNFAAELAPKNIRVNCLAPGLIKTRFSS 203
>Q8FHD2:YDFG_ECOL6 NADP-dependent L-serine/L-allo-threonine dehydrogenase ydfG -| Escherichia coli O6 Length = 248 Score = 84.0 bits (206), Expect = 1e-15 Identities = 61/248 (24%), Positives = 118/248 (47%), Gaps = 2/248 (0%) Frame = +1 Query: 181 VVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLS 360 +V +TGA+ G GE ++ +F G K+I + R +E L+ +K + ++++V Sbjct: 2 IVLVTGATAGFGECITRRFIQQGHKVIATGRRQERLQELKDELGDNLYIAQLDV------ 55 Query: 361 SDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITL 540 + +++E++ S + +S+ ID +++NA A + + E + N G + + Sbjct: 56 RNRAAIEEMLASLPAEWSN--IDILVNNAGLALGMEPAHKASIEDWETMIDTNNKGLVYM 113 Query: 541 TRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIKVT 720 TR + P M++R GH + + S AG P G +Y A+K + + +LR++L ++VT Sbjct: 114 TRAVLPGMVERNHGHIINIGSTAGSWPYAGGNVYGATKAFVRQFSLNLRTDLHGTAVRVT 173 Query: 721 VVCPGPIETPESSGATSSSQRHSSEKRVSVERCAELTIVAATHGLKEA--WISYQPVLAV 894 + PG + G T S E+ + T+ + EA W+S P Sbjct: 174 DIEPGLV------GGTEFSNVRFKGDDGKAEKTYQNTVALTPEDVSEAVWWVSTLPAHVN 227 Query: 895 MYVVQYMP 918 + ++ MP Sbjct: 228 INTLEMMP 235
>Q29608:DHI1_SAISC Corticosteroid 11-beta-dehydrogenase isozyme 1 - Saimiri sciureus| (Common squirrel monkey) Length = 291 Score = 84.0 bits (206), Expect = 1e-15 Identities = 65/224 (29%), Positives = 110/224 (49%), Gaps = 2/224 (0%) Frame = +1 Query: 157 RRDKVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKV 336 R + + GK V +TGAS+GIG ++ A +GA ++++AR+KE L++V + + S Sbjct: 28 RPEMLQGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAH 87 Query: 337 EVLPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKV 516 + D ++ V A L G+D ++ N + ++ + +V Sbjct: 88 YIA--GTMEDMTFAEQFVAQAGKLMG--GLDMLILNH-ITNTSLNFFHDDIHHVRKSMEV 142 Query: 517 NVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSE- 693 N + LT P ML + G V++SS AGKV P + YSASK AL G+F+S+R E Sbjct: 143 NFLSYVVLTVAAMP-MLKQSNGSIVIVSSVAGKVAYPMISAYSASKFALYGFFSSIRKEY 201 Query: 694 -LCTKGIKVTVVCPGPIETPESSGATSSSQRHSSEKRVSVERCA 822 + + +T+ G I+T + A S + + ++ E CA Sbjct: 202 LMSEVNVSITLCVLGLIDTDTAMKAVSGIIKMQAARK---EECA 242
>Q6QLL4:DHI1_CAVPO Corticosteroid 11-beta-dehydrogenase isozyme 1 - Cavia porcellus| (Guinea pig) Length = 300 Score = 84.0 bits (206), Expect = 1e-15 Identities = 64/207 (30%), Positives = 105/207 (50%), Gaps = 2/207 (0%) Frame = +1 Query: 157 RRDKVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKV 336 R + + GK V +TGAS+GIG ++ A +GA ++++AR+KE L++V + S Sbjct: 28 RPEMLQGKKVIVTGASKGIGREIAYHLAKMGAHVVVTARSKEALQKVVARCLELGAASAH 87 Query: 337 EVLPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKV 516 + D +E V A +L G+D ++ N + + ++ + +V Sbjct: 88 YIAGS--MEDMTFAEEFVAEAGNLMG--GLDMLILNHVLYN-RLTFFHGEIDNVRKSMEV 142 Query: 517 NVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSEL 696 N + L+ P ML + G V+SS AGK+ P A YSASK AL+G+F++LRSE Sbjct: 143 NFHSFVVLSVAAMP-MLMQSQGSIAVVSSVAGKITYPLIAPYSASKFALDGFFSTLRSEF 201 Query: 697 CTK--GIKVTVVCPGPIETPESSGATS 771 + +T+ G I+T + ATS Sbjct: 202 LVNKVNVSITLCILGLIDTETAIKATS 228
>P51975:DHI1_SHEEP Corticosteroid 11-beta-dehydrogenase isozyme 1 - Ovis aries (Sheep)| Length = 292 Score = 83.6 bits (205), Expect = 2e-15 Identities = 69/224 (30%), Positives = 112/224 (50%), Gaps = 2/224 (0%) Frame = +1 Query: 157 RRDKVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKV 336 R + + GK V +TGAS+GIG ++ A +GA ++++AR++E L++V + S Sbjct: 28 RPEMLRGKRVIVTGASKGIGREMAYHLARMGAHVVVTARSEESLKKVVSRCLELGAASAH 87 Query: 337 EVLPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKV 516 V + ++ V A L G+D ++ N P R L+ + +V Sbjct: 88 YVA--GTMENMTFAEQFVAKAGELVG--GLDMLILNHINYTPLR-VFSNDIHLLRRSLEV 142 Query: 517 NVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSEL 696 N+ + L+ P ML + G VV+SS AGK+ P A YSASK AL+G+F+SLR+E Sbjct: 143 NLLSYVVLSTAALP-MLKQTSGSIVVVSSVAGKIACPLAAAYSASKFALDGFFSSLRTEY 201 Query: 697 -CTK-GIKVTVVCPGPIETPESSGATSSSQRHSSEKRVSVERCA 822 TK + +T+ G I+T + A + + + E CA Sbjct: 202 EATKVNVSITLCILGLIDTDTAMKAVAGIYNAEASPK---EECA 242
>P80873:GS39_BACSU General stress protein 39 - Bacillus subtilis| Length = 286 Score = 82.8 bits (203), Expect = 3e-15 Identities = 57/198 (28%), Positives = 98/198 (49%), Gaps = 2/198 (1%) Frame = +1 Query: 163 DKVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNK-EELERVKHNIMSKHPDSKVE 339 DK+ GKV ITG GIG +S+ +A GA + + +++ E+ E K + + K Sbjct: 38 DKLKGKVALITGGDSGIGRAVSVAYAKEGADIAIVYKDEHEDAEETKKRV--EQEGVKCL 95 Query: 340 VLPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVN 519 ++ D+ +E + V + + L G+D +++NA + PK + T E L TFK N Sbjct: 96 LIAGDVGEEEFCNEAVEKTVKEL---GGLDILVNNAGEQHPKESIKDITSEQLHRTFKTN 152 Query: 520 VFGTITLTRLLAPFMLDRGMGHFVVMSSAAGK-VPTPGQALYSASKHALNGYFASLRSEL 696 + LT+ ++ G ++ +++ V P Y+A+K A+N + ++ L Sbjct: 153 FYSQFYLTKKAIDYLKP---GSAIINTTSINPYVGNPTLIDYTATKGAINAFTRTMAQAL 209 Query: 697 CTKGIKVTVVCPGPIETP 750 GI+V V PGPI TP Sbjct: 210 VKDGIRVNAVAPGPIWTP 227
>P0AEK3:FABG_SHIFL 3-oxoacyl-[acyl-carrier-protein] reductase - Shigella flexneri| Length = 244 Score = 82.8 bits (203), Expect = 3e-15 Identities = 57/204 (27%), Positives = 101/204 (49%) Frame = +1 Query: 172 DGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPM 351 +GK+ +TGASRGIG ++ A+ GAK+I +A ++ + + + + + V Sbjct: 4 EGKIALVTGASRGIGRAIAETLAARGAKVIGTATSENGAQAISDYLGANGKGLMLNV--- 60 Query: 352 DLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGT 531 +D S++ V+ + F +D +++NA R + +E + N+ Sbjct: 61 ---TDPASIESVLEKIRAEFGE--VDILVNNAGITRDNL-LMRMKDEEWNDIIETNLSSV 114 Query: 532 ITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 711 L++ + M+ + G + + S G + GQA Y+A+K L G+ SL E+ ++GI Sbjct: 115 FRLSKAVMRAMMKKRHGRIITIGSVVGTMGNGGQANYAAAKAGLIGFSKSLAREVASRGI 174 Query: 712 KVTVVCPGPIETPESSGATSSSQR 783 V VV PG IET + + A S QR Sbjct: 175 TVNVVAPGFIET-DMTRALSDDQR 197
>P0AEK2:FABG_ECOLI 3-oxoacyl-[acyl-carrier-protein] reductase - Escherichia coli| Length = 244 Score = 82.8 bits (203), Expect = 3e-15 Identities = 57/204 (27%), Positives = 101/204 (49%) Frame = +1 Query: 172 DGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPM 351 +GK+ +TGASRGIG ++ A+ GAK+I +A ++ + + + + + V Sbjct: 4 EGKIALVTGASRGIGRAIAETLAARGAKVIGTATSENGAQAISDYLGANGKGLMLNV--- 60 Query: 352 DLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGT 531 +D S++ V+ + F +D +++NA R + +E + N+ Sbjct: 61 ---TDPASIESVLEKIRAEFGE--VDILVNNAGITRDNL-LMRMKDEEWNDIIETNLSSV 114 Query: 532 ITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 711 L++ + M+ + G + + S G + GQA Y+A+K L G+ SL E+ ++GI Sbjct: 115 FRLSKAVMRAMMKKRHGRIITIGSVVGTMGNGGQANYAAAKAGLIGFSKSLAREVASRGI 174 Query: 712 KVTVVCPGPIETPESSGATSSSQR 783 V VV PG IET + + A S QR Sbjct: 175 TVNVVAPGFIET-DMTRALSDDQR 197
>Q8VCR2:DHB13_MOUSE 17-beta hydroxysteroid dehydrogenase 13 precursor - Mus musculus| (Mouse) Length = 304 Score = 82.8 bits (203), Expect = 3e-15 Identities = 62/201 (30%), Positives = 98/201 (48%), Gaps = 4/201 (1%) Frame = +1 Query: 157 RRDKVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKV 336 RR V G+ V ITGA GIG + + +FA ++L+L NK +E + + V Sbjct: 30 RRKSVTGQTVLITGAGHGIGRLTAYEFAKQKSRLVLWDINKRGVEETADKC--RKLGAVV 87 Query: 337 EVLPMDLSSDEKSLKEVVHSAESLFSSAG-IDYMMHNAAFERPKRGALEETEEGLKATFK 513 V +D S+ E+ +S + + G ++ +++NA P L +E + TF+ Sbjct: 88 HVFVVDCSNRA----EIYNSVDQVKREVGDVEIVVNNAGAIYPA-DLLSAKDEEITKTFE 142 Query: 514 VNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSE 693 VN+ G + + L P ML R GH V ++S G P Y +SK A G+ +L +E Sbjct: 143 VNILGHFWIIKALLPSMLRRNSGHIVTVASVCGHGVIPYLIPYCSSKFAAVGFHRALTAE 202 Query: 694 LCT---KGIKVTVVCPGPIET 747 L T GIK + +CP + T Sbjct: 203 LDTLGKTGIKTSCLCPVFVNT 223
>O57314:DHB12_ANAPL Estradiol 17-beta-dehydrogenase 12 - Anas platyrhynchos (Domestic| duck) Length = 312 Score = 82.8 bits (203), Expect = 3e-15 Identities = 61/210 (29%), Positives = 101/210 (48%), Gaps = 5/210 (2%) Frame = +1 Query: 190 ITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDE 369 +TGA+ GIG+ + + A G K+ L +R+KE+L++V I ++ + +V+ D E Sbjct: 53 VTGATDGIGKAYAKELAKRGMKVALISRSKEKLDQVAGEITEQY-GVETKVIVADFGERE 111 Query: 370 KSLKEVVHSAESL-----FSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTI 534 + E L ++ GI Y + P + ++ + +N+ Sbjct: 112 DIYDRIRAGLEGLEIGVLVNNVGISYSYPEYFIDVP------DLDKTIDKMININIMSVC 165 Query: 535 TLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 714 +TRL+ P ML+R G + +SSAAG PTP LYSASK ++ + L +E +KGI Sbjct: 166 KMTRLVLPGMLERSKGVILNISSAAGMYPTPLLTLYSASKAFVDYFSRGLHAEYKSKGII 225 Query: 715 VTVVCPGPIETPESSGATSSSQRHSSEKRV 804 V V P + T S + S + + E V Sbjct: 226 VQSVMPYYVATKMSKISKPSFDKPTPETYV 255
>P39831:YDFG_ECOLI NADP-dependent L-serine/L-allo-threonine dehydrogenase ydfG -| Escherichia coli Length = 248 Score = 82.4 bits (202), Expect = 4e-15 Identities = 60/248 (24%), Positives = 117/248 (47%), Gaps = 2/248 (0%) Frame = +1 Query: 181 VVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLS 360 +V +TGA+ G GE ++ +F G K+I + R +E L+ +K + ++++V Sbjct: 2 IVLVTGATAGFGECITRRFIQQGHKVIATGRRQERLQELKDELGDNLYIAQLDV------ 55 Query: 361 SDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITL 540 + +++E++ S + + + ID +++NA A + + E + N G + + Sbjct: 56 RNRAAIEEMLASLPAEWCN--IDILVNNAGLALGMEPAHKASVEDWETMIDTNNKGLVYM 113 Query: 541 TRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIKVT 720 TR + P M++R GH + + S AG P G +Y A+K + + +LR++L ++VT Sbjct: 114 TRAVLPGMVERNHGHIINIGSTAGSWPYAGGNVYGATKAFVRQFSLNLRTDLHGTAVRVT 173 Query: 721 VVCPGPIETPESSGATSSSQRHSSEKRVSVERCAELTIVAATHGLKEA--WISYQPVLAV 894 + PG + G T S E+ + T+ + EA W+S P Sbjct: 174 DIEPGLV------GGTEFSNVRFKGDDGKAEKTYQNTVALTPEDVSEAVWWVSTLPAHVN 227 Query: 895 MYVVQYMP 918 + ++ MP Sbjct: 228 INTLEMMP 235
>Q92EK7:Y452_LISIN Uncharacterized oxidoreductase Lin0452 - Listeria innocua| Length = 248 Score = 82.4 bits (202), Expect = 4e-15 Identities = 61/199 (30%), Positives = 95/199 (47%), Gaps = 6/199 (3%) Frame = +1 Query: 169 VDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLP 348 + KV+ ITGAS GIGE ++ A GAKL+L+AR E+LE++ I + ++ Sbjct: 3 IKNKVIIITGASSGIGEATAILLAEKGAKLVLAARRVEKLEKIVQTIKASSGEAIFAKTD 62 Query: 349 MDLSSDEKSLKEVV----HSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKV 516 + D K L E+ +++F +AGI M N+ AL+E E + + Sbjct: 63 VTKREDNKKLVELAIERYGKVDAIFLNAGI---MPNSPL-----SALKEDE--WEQMIDI 112 Query: 517 NVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSEL 696 N+ G + + P + + GH + SS AG PG A+Y A+K A+ LR E Sbjct: 113 NIKGVLNGIAAVLPSFIAQKSGHIIATSSVAGLKAYPGGAVYGATKWAVRDLMEVLRMES 172 Query: 697 CTKG--IKVTVVCPGPIET 747 +G I+ + P I T Sbjct: 173 AQEGTNIRTATIYPAAINT 191
>Q9GKX2:DHRS4_RABIT Dehydrogenase/reductase SDR family member 4 - Oryctolagus cuniculus| (Rabbit) Length = 260 Score = 82.4 bits (202), Expect = 4e-15 Identities = 59/204 (28%), Positives = 99/204 (48%) Frame = +1 Query: 136 LLSCGRPRRDKVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMS 315 + S G RRD + KV +T ++ GIG ++ + A GA +++S+R ++ ++R + + Sbjct: 1 MASSGVTRRDPLANKVAIVTASTDGIGLAIARRLAQDGAHVVISSRKQQNVDRAVAALQA 60 Query: 316 KHPDSKVEVLPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEG 495 + V + + D + L A +L GID ++ NAA ++ TEE Sbjct: 61 EGLSVTGTVCHVGKAEDRERLV-----ATALNLHGGIDILVSNAAVNPFFGKLMDVTEEV 115 Query: 496 LKATFKVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYF 675 +NV +T+ + P M RG G V+++S A P G Y+ SK AL G Sbjct: 116 WDKILDINVKAMALMTKAVVPEMEKRGGGSVVIVASIAAFNPFSGLGPYNVSKTALVGLT 175 Query: 676 ASLRSELCTKGIKVTVVCPGPIET 747 +L EL + I+V + PG I+T Sbjct: 176 KNLALELAAQNIRVNCLAPGLIKT 199
>P16544:ACT3_STRCO Putative ketoacyl reductase - Streptomyces coelicolor| Length = 261 Score = 82.4 bits (202), Expect = 4e-15 Identities = 67/218 (30%), Positives = 104/218 (47%), Gaps = 4/218 (1%) Frame = +1 Query: 172 DGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPM 351 D +V +TGA+ GIG ++ + G ++ + AR +E L + ++ Sbjct: 5 DSEVALVTGATSGIGLEIARRLGKEGLRVFVCARGEEGLRTTLKELREAGVEADGR---- 60 Query: 352 DLSSDEKSLKEVVHSAESLFSSAG-IDYMMHNAAFERPKRGALEETEEGLKA-TFKVNVF 525 + D +S+ E+ ++ G +D +++NA RP GA E + L + N+ Sbjct: 61 --TCDVRSVPEIEALVAAVVERYGPVDVLVNNAG--RPGGGATAELADELWLDVVETNLT 116 Query: 526 GTITLTR--LLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELC 699 G +T+ L A ML+RG G V ++S GK A YSASKH + G+ +L EL Sbjct: 117 GVFRVTKQVLKAGGMLERGTGRIVNIASTGGKQGVVHAAPYSASKHGVVGFTKALGLELA 176 Query: 700 TKGIKVTVVCPGPIETPESSGATSSSQRHSSEKRVSVE 813 GI V VCPG +ETP A S + +S VS E Sbjct: 177 RTGITVNAVCPGFVETPM---AASVREHYSDIWEVSTE 211
>Q8X505:YDFG_ECO57 NADP-dependent L-serine/L-allo-threonine dehydrogenase ydfG -| Escherichia coli O157:H7 Length = 248 Score = 82.0 bits (201), Expect = 5e-15 Identities = 60/248 (24%), Positives = 117/248 (47%), Gaps = 2/248 (0%) Frame = +1 Query: 181 VVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLS 360 +V +TGA+ G GE ++ +F G K+I + R +E L+ +K + ++++V Sbjct: 2 IVLVTGATAGFGECITRRFIQQGHKVIATGRRQERLQELKDELGDNLYIAQLDV------ 55 Query: 361 SDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITL 540 + +++E++ S + + + ID +++NA A + + E + N G + + Sbjct: 56 RNRAAIEEMLASLPAEWCN--IDILVNNAGLALGMEPAHKASIEDWETMIDTNNKGLVYM 113 Query: 541 TRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIKVT 720 TR + P M++R GH + + S AG P G +Y A+K + + +LR++L ++VT Sbjct: 114 TRAVLPGMVERNHGHIINIGSTAGSWPYAGGNVYGATKAFVRQFSLNLRTDLHGTAVRVT 173 Query: 721 VVCPGPIETPESSGATSSSQRHSSEKRVSVERCAELTIVAATHGLKEA--WISYQPVLAV 894 + PG + G T S E+ + T+ + EA W+S P Sbjct: 174 DIEPGLV------GGTEFSNVRFKGDDGKAEKTYQNTVALTPEDVSEAVWWVSTLPAHVN 227 Query: 895 MYVVQYMP 918 + ++ MP Sbjct: 228 INTLEMMP 235
>P55434:Y4EK_RHISN Uncharacterized short-chain type dehydrogenase/reductase y4eK -| Rhizobium sp. (strain NGR234) Length = 248 Score = 82.0 bits (201), Expect = 5e-15 Identities = 50/190 (26%), Positives = 94/190 (49%) Frame = +1 Query: 178 KVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDL 357 +V +TGAS GIG+ ++++ AS G +++ R++ L+ + H + + + DL Sbjct: 8 EVALVTGASSGIGKAIALELASAGLRVLALGRDRAALDEL-------HSTAGIVPVVFDL 60 Query: 358 SSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTIT 537 S V + ID +++NA ++ +E+ + A +N+ Sbjct: 61 SD--------VSEVYGKIAGEKIDVLVNNAGLLTASASLVDLSEDDIDAMIDINIRSVFK 112 Query: 538 LTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIKV 717 LTR + M++R GH S+ G P P ++Y A+K A++ + ++LR +L I+V Sbjct: 113 LTRHVLKQMIERRRGHIFFTGSSGGLAPHPNSSVYGATKAAVSLFSSALRCDLIGLPIRV 172 Query: 718 TVVCPGPIET 747 T + PG +ET Sbjct: 173 TELFPGRVET 182
>Q6R0J2:DHI1_MESAU Corticosteroid 11-beta-dehydrogenase isozyme 1 - Mesocricetus| auratus (Golden hamster) Length = 292 Score = 81.6 bits (200), Expect = 7e-15 Identities = 64/207 (30%), Positives = 103/207 (49%), Gaps = 2/207 (0%) Frame = +1 Query: 157 RRDKVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKV 336 R + + GK V +TGAS+GIG ++ + +GA ++L+AR++E L++V + S Sbjct: 28 RPEMLQGKKVIVTGASKGIGREMAYHLSEMGAHVVLTARSEEGLQKVASRCLELGAASAH 87 Query: 337 EVLPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKV 516 + D ++ V A L G+D ++ N +E L+ +V Sbjct: 88 YIA--GTMEDMTFAEQFVLKAGKLMG--GLDMLILNHITYTSMNFFRDEIH-ALRKAMEV 142 Query: 517 NVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSE- 693 N + ++ P ML + G VV+SS AGK+ P A YSASK AL+G+F+SLR E Sbjct: 143 NFISYVVMSVAALP-MLKQSNGSIVVVSSIAGKMAHPLVASYSASKFALDGFFSSLRREH 201 Query: 694 -LCTKGIKVTVVCPGPIETPESSGATS 771 + + +T+ G I T + ATS Sbjct: 202 GVTNVNVSITLCVLGLINTETAMKATS 228
>P37959:YUSZ_BACSU Uncharacterized oxidoreductase yusZ - Bacillus subtilis| Length = 280 Score = 81.3 bits (199), Expect = 9e-15 Identities = 55/191 (28%), Positives = 103/191 (53%), Gaps = 1/191 (0%) Frame = +1 Query: 178 KVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDL 357 K+ +TGAS G G + +++ A +I ++R E+ E+++ + + + + +D+ Sbjct: 4 KIAIVTGASSGFGLLAAVKLAR-SFFVIATSRQPEKAEQLRELAAAHNVSDSIHITALDV 62 Query: 358 SSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETE-EGLKATFKVNVFGTI 534 + DE+S +V +++ + A ID +++NA G +E+ E + F+ NVFG I Sbjct: 63 T-DEQS---IVSFGKAVSAYAPIDLLVNNAG--TAYGGFIEDVPMEHFRQQFETNVFGVI 116 Query: 535 TLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 714 +T+ + P++ G + +SS +G P + Y +SKHAL G+ SLR EL GI+ Sbjct: 117 HVTKTVLPYIRKHGGAKIINVSSISGLTGFPALSPYVSSKHALEGFSESLRIELLPFGIE 176 Query: 715 VTVVCPGPIET 747 ++ PG +T Sbjct: 177 TALIEPGSYKT 187
>Q83RE8:YDFG_SHIFL NADP-dependent L-serine/L-allo-threonine dehydrogenase ydfG -| Shigella flexneri Length = 248 Score = 81.3 bits (199), Expect = 9e-15 Identities = 60/248 (24%), Positives = 117/248 (47%), Gaps = 2/248 (0%) Frame = +1 Query: 181 VVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLS 360 +V +TGA+ G GE ++ +F G K+I + R +E L+ + + ++++V Sbjct: 2 IVLVTGATAGFGECITRRFIQQGHKVIATGRRQERLQELTDELGDNLYIAQLDV------ 55 Query: 361 SDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITL 540 + +++E++ S + +S+ ID +++NA A + + E + N G + + Sbjct: 56 RNRAAIEEMLASLPAEWSN--IDILVNNAGLALGMEPAHKASVEDWETMIDTNNKGLVYM 113 Query: 541 TRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIKVT 720 TR + P M++R GH + + S AG P G +Y A+K + + +LR++L ++VT Sbjct: 114 TRAVLPGMVERNHGHIINIGSTAGSWPYAGGNVYGATKAFVRQFSLNLRTDLHGTTVRVT 173 Query: 721 VVCPGPIETPESSGATSSSQRHSSEKRVSVERCAELTIVAATHGLKEA--WISYQPVLAV 894 + PG + G T S E+ + T+ + EA W+S P Sbjct: 174 DIEPGLV------GGTEFSNVRFKGDDGKAEKTYQNTVALTPEDVSEAVWWVSTLPAHVN 227 Query: 895 MYVVQYMP 918 + ++ MP Sbjct: 228 INTLEMMP 235
>P25145:Y432_LISMO Uncharacterized oxidoreductase Lmo0432 - Listeria monocytogenes| Length = 248 Score = 81.3 bits (199), Expect = 9e-15 Identities = 60/199 (30%), Positives = 95/199 (47%), Gaps = 6/199 (3%) Frame = +1 Query: 169 VDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLP 348 + KV+ ITGAS GIG+ ++ A GAKL+L+AR E+LE++ I + ++ Sbjct: 3 IKNKVIIITGASSGIGKATALLLAEKGAKLVLAARRVEKLEKIVQTIKANSGEAIFAKTD 62 Query: 349 MDLSSDEKSLKEVV----HSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKV 516 + D K L E+ +++F +AGI M N+ AL+E E + + Sbjct: 63 VTKREDNKKLVELAIERYGKVDAIFLNAGI---MPNSPL-----SALKEDE--WEQMIDI 112 Query: 517 NVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSEL 696 N+ G + + P + + GH + SS AG PG A+Y A+K A+ LR E Sbjct: 113 NIKGVLNGIAAVLPSFIAQKSGHIIATSSVAGLKAYPGGAVYGATKWAVRDLMEVLRMES 172 Query: 697 CTKG--IKVTVVCPGPIET 747 +G I+ + P I T Sbjct: 173 AQEGTNIRTVTIYPAAINT 191
>Q9WYG0:Y325_THEMA Uncharacterized oxidoreductase TM_0325 - Thermotoga maritima| Length = 251 Score = 81.3 bits (199), Expect = 9e-15 Identities = 68/198 (34%), Positives = 100/198 (50%), Gaps = 2/198 (1%) Frame = +1 Query: 175 GKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMD 354 GKVV ITGA GIG+ ++ FA GAK+ ++ ++E+ + I S + + D Sbjct: 5 GKVVLITGAGSGIGKKAAVMFAERGAKVAINDISEEKGKETVELIKSM--GGEAAFIFGD 62 Query: 355 LSSD-EKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEET-EEGLKATFKVNVFG 528 ++ D E+ +K+ V + L D +++NA G +EET EE T VNV G Sbjct: 63 VAKDAEQIVKKTVETFGRL------DILVNNAGIV--PYGNIEETSEEDFDKTMAVNVKG 114 Query: 529 TITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKG 708 L++ M +G G V +SS AG + P + +YS SK AL G SL + G Sbjct: 115 PFLLSKYAVEQMKKQGGGVIVNVSSEAGLIGIPRRCVYSVSKAALLGLTRSLAVDYVDYG 174 Query: 709 IKVTVVCPGPIETPESSG 762 I+V VCPG T +S G Sbjct: 175 IRVNAVCPG---TTQSEG 189
>P0A2C9:FABG_SALTY 3-oxoacyl-[acyl-carrier-protein] reductase - Salmonella typhimurium| Length = 244 Score = 81.3 bits (199), Expect = 9e-15 Identities = 55/204 (26%), Positives = 101/204 (49%) Frame = +1 Query: 172 DGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPM 351 +GK+ +TGASRGIG ++ + GAK+I +A ++ + + + + + V Sbjct: 4 EGKIALVTGASRGIGRAIAETLVARGAKVIGTATSENGAKNISDYLGANGKGLMLNV--- 60 Query: 352 DLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGT 531 +D S++ V+ + + F +D +++NA R + ++ + N+ Sbjct: 61 ---TDPASIESVLENIRAEFGE--VDILVNNAGITRDNL-LMRMKDDEWNDIIETNLSSV 114 Query: 532 ITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 711 L++ + M+ + G + + S G + GQA Y+A+K L G+ SL E+ ++GI Sbjct: 115 FRLSKAVMRAMMKKRCGRIITIGSVVGTMGNAGQANYAAAKAGLIGFSKSLAREVASRGI 174 Query: 712 KVTVVCPGPIETPESSGATSSSQR 783 V VV PG IET + + A S QR Sbjct: 175 TVNVVAPGFIET-DMTRALSDDQR 197
>P0A2D0:FABG_SALTI 3-oxoacyl-[acyl-carrier-protein] reductase - Salmonella typhi| Length = 244 Score = 81.3 bits (199), Expect = 9e-15 Identities = 55/204 (26%), Positives = 101/204 (49%) Frame = +1 Query: 172 DGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPM 351 +GK+ +TGASRGIG ++ + GAK+I +A ++ + + + + + V Sbjct: 4 EGKIALVTGASRGIGRAIAETLVARGAKVIGTATSENGAKNISDYLGANGKGLMLNV--- 60 Query: 352 DLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGT 531 +D S++ V+ + + F +D +++NA R + ++ + N+ Sbjct: 61 ---TDPASIESVLENIRAEFGE--VDILVNNAGITRDNL-LMRMKDDEWNDIIETNLSSV 114 Query: 532 ITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 711 L++ + M+ + G + + S G + GQA Y+A+K L G+ SL E+ ++GI Sbjct: 115 FRLSKAVMRAMMKKRCGRIITIGSVVGTMGNAGQANYAAAKAGLIGFSKSLAREVASRGI 174 Query: 712 KVTVVCPGPIETPESSGATSSSQR 783 V VV PG IET + + A S QR Sbjct: 175 TVNVVAPGFIET-DMTRALSDDQR 197
>P37440:UCPA_ECOLI Oxidoreductase ucpA - Escherichia coli| Length = 263 Score = 80.9 bits (198), Expect = 1e-14 Identities = 62/211 (29%), Positives = 98/211 (46%), Gaps = 1/211 (0%) Frame = +1 Query: 166 KVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVL 345 K+ GK ITGA +GIGE ++ FA GA LIL + E +E++ + + V Sbjct: 3 KLTGKTALITGALQGIGEGIARTFARHGANLILLDISPE-IEKLADELCGRGHRCTAVVA 61 Query: 346 PMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVF 525 + D S+ + A+ ID +++NA R L+ +++ +N+ Sbjct: 62 DV---RDPASVAAAIKRAKE--KEGRIDILVNNAGVCR-LGSFLDMSDDDRDFHIDINIK 115 Query: 526 GTITLTRLLAPFMLDRGMGHFVVMSSAAGK-VPTPGQALYSASKHALNGYFASLRSELCT 702 G +T+ + P M+ R G V+MSS G V PG+ Y+ +K A+ G SL E Sbjct: 116 GVWNVTKAVLPEMIARKDGRIVMMSSVTGDMVADPGETAYALTKAAIVGLTKSLAVEYAQ 175 Query: 703 KGIKVTVVCPGPIETPESSGATSSSQRHSSE 795 GI+V +CPG + TP + S E Sbjct: 176 SGIRVNAICPGYVRTPMAESIARQSNPEDPE 206
>Q8XBJ4:UCPA_ECO57 Oxidoreductase ucpA - Escherichia coli O157:H7| Length = 263 Score = 80.9 bits (198), Expect = 1e-14 Identities = 62/211 (29%), Positives = 98/211 (46%), Gaps = 1/211 (0%) Frame = +1 Query: 166 KVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVL 345 K+ GK ITGA +GIGE ++ FA GA LIL + E +E++ + + V Sbjct: 3 KLTGKTALITGALQGIGEGIARTFARHGANLILLDISPE-IEKLADELCGRGHRCTAVVA 61 Query: 346 PMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVF 525 + D S+ + A+ ID +++NA R L+ +++ +N+ Sbjct: 62 DV---RDPASVAAAIKRAKE--KEGRIDILVNNAGVCR-LGSFLDMSDDDRDFHIDINIK 115 Query: 526 GTITLTRLLAPFMLDRGMGHFVVMSSAAGK-VPTPGQALYSASKHALNGYFASLRSELCT 702 G +T+ + P M+ R G V+MSS G V PG+ Y+ +K A+ G SL E Sbjct: 116 GVWNVTKAVLPEMIARKDGRIVMMSSVTGDMVADPGETAYALTKAAIVGLTKSLAVEYAQ 175 Query: 703 KGIKVTVVCPGPIETPESSGATSSSQRHSSE 795 GI+V +CPG + TP + S E Sbjct: 176 SGIRVNAICPGYVRTPMAESIARQSNPEDPE 206
>Q28IU1:DHB12_XENTR Estradiol 17-beta-dehydrogenase 12 - Xenopus tropicalis (Western| clawed frog) (Silurana tropicalis) Length = 320 Score = 80.9 bits (198), Expect = 1e-14 Identities = 59/194 (30%), Positives = 98/194 (50%), Gaps = 3/194 (1%) Frame = +1 Query: 175 GKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMD 354 GK +TGA+ GIG+ + + A G ++L +R+ E+LE V I K KVE Sbjct: 56 GKWAVVTGATDGIGKAYAEELAKRGMNIVLISRSPEKLEEVAKQIKEKF---KVET--KI 110 Query: 355 LSSDEKSLKEVVHSAESLFSSAGIDYMMHNA--AFERPKRGA-LEETEEGLKATFKVNVF 525 +++D E+ ES I +++N ++E P+ + + E L +N+ Sbjct: 111 IAADFGKPTEIYGRIESGLRDLEIGVLVNNVGVSYEHPEYFLEIPDLENTLDKMININIT 170 Query: 526 GTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTK 705 +TRL+ P ML RG G + +SSA+G P P +YSA+K ++ + L++E +K Sbjct: 171 SVCQMTRLVLPGMLGRGRGVILNISSASGMYPVPLLTVYSATKAFVDFFSRGLQAEYRSK 230 Query: 706 GIKVTVVCPGPIET 747 G+ V V P + T Sbjct: 231 GVTVQSVLPFYVAT 244
>P69936:YDFG_SALTY NADP-dependent L-serine/L-allo-threonine dehydrogenase ydfG -| Salmonella typhimurium Length = 248 Score = 80.5 bits (197), Expect = 2e-14 Identities = 62/248 (25%), Positives = 115/248 (46%), Gaps = 2/248 (0%) Frame = +1 Query: 181 VVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLS 360 +V +TGA+ G GE ++ +F G K+I + R E L+ +K + ++++V Sbjct: 2 IVLVTGATAGFGECIARRFVENGHKVIATGRRHERLQALKDELGENVLTAQLDV------ 55 Query: 361 SDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITL 540 + +++E++ S + + ID +++NA A + + E + N G I + Sbjct: 56 RNRAAIEEMMASLPAQWRD--IDVLVNNAGLALGLEPAHKASVEDWETMIDTNNKGLIYM 113 Query: 541 TRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIKVT 720 TR + P M++R GH + + S AG P G +Y A+K + + +LR++L ++VT Sbjct: 114 TRAVLPGMVERNRGHIINIGSTAGSWPYAGGNVYGATKAFVRQFSLNLRTDLHGTAVRVT 173 Query: 721 VVCPGPIETPESSGATSSSQRHSSEKRVSVERCAELTIVAATHGLKEA--WISYQPVLAV 894 + PG + G SS R + + E T + EA W++ P Sbjct: 174 DIEPGLV-----GGTEFSSVRFKGDDE-KAGKTYENTTALTPEDITEAVWWVATLPAHVN 227 Query: 895 MYVVQYMP 918 + V+ MP Sbjct: 228 INTVEMMP 235
>P69935:YDFG_SALTI NADP-dependent L-serine/L-allo-threonine dehydrogenase ydfG -| Salmonella typhi Length = 248 Score = 80.5 bits (197), Expect = 2e-14 Identities = 62/248 (25%), Positives = 115/248 (46%), Gaps = 2/248 (0%) Frame = +1 Query: 181 VVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLS 360 +V +TGA+ G GE ++ +F G K+I + R E L+ +K + ++++V Sbjct: 2 IVLVTGATAGFGECIARRFVENGHKVIATGRRHERLQALKDELGENVLTAQLDV------ 55 Query: 361 SDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITL 540 + +++E++ S + + ID +++NA A + + E + N G I + Sbjct: 56 RNRAAIEEMMASLPAQWRD--IDVLVNNAGLALGLEPAHKASVEDWETMIDTNNKGLIYM 113 Query: 541 TRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIKVT 720 TR + P M++R GH + + S AG P G +Y A+K + + +LR++L ++VT Sbjct: 114 TRAVLPGMVERNRGHIINIGSTAGSWPYAGGNVYGATKAFVRQFSLNLRTDLHGTAVRVT 173 Query: 721 VVCPGPIETPESSGATSSSQRHSSEKRVSVERCAELTIVAATHGLKEA--WISYQPVLAV 894 + PG + G SS R + + E T + EA W++ P Sbjct: 174 DIEPGLV-----GGTEFSSVRFKGDDE-KAGKTYENTTALTPEDITEAVWWVATLPAHVN 227 Query: 895 MYVVQYMP 918 + V+ MP Sbjct: 228 INTVEMMP 235
>Q9KQH7:FABG_VIBCH 3-oxoacyl-[acyl-carrier-protein] reductase - Vibrio cholerae| Length = 244 Score = 80.5 bits (197), Expect = 2e-14 Identities = 57/225 (25%), Positives = 111/225 (49%) Frame = +1 Query: 169 VDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLP 348 ++GKV +TGASRGIG+ ++ A GAK+I +A ++ + + + + V Sbjct: 3 LEGKVALVTGASRGIGKAIAELLAERGAKVIGTATSESGAQAISDYLGDNGKGMALNV-- 60 Query: 349 MDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFG 528 ++ +S++ V+ + F G+D +++NA R + EE + N+ Sbjct: 61 ----TNPESIEAVLKAITDEFG--GVDILVNNAGITRDNL-LMRMKEEEWSDIMETNLTS 113 Query: 529 TITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKG 708 L++ + M+ + G + + S G + GQA Y+A+K + G+ S+ E+ ++G Sbjct: 114 IFRLSKAVLRGMMKKRQGRIINVGSVVGTMGNAGQANYAAAKAGVIGFTKSMAREVASRG 173 Query: 709 IKVTVVCPGPIETPESSGATSSSQRHSSEKRVSVERCAELTIVAA 843 + V V PG IET + + A + QR ++ +V R + +A+ Sbjct: 174 VTVNTVAPGFIET-DMTKALNDEQRTATLAQVPAGRLGDPREIAS 217
>P0A0I0:FABG_STAAW 3-oxoacyl-[acyl-carrier-protein] reductase - Staphylococcus aureus| (strain MW2) Length = 246 Score = 80.1 bits (196), Expect = 2e-14 Identities = 67/225 (29%), Positives = 103/225 (45%), Gaps = 2/225 (0%) Frame = +1 Query: 178 KVVWITGASRGIGEVLSMQFASLGAKLILS-ARNKEELERVKHNIMSKHPDS-KVEVLPM 351 K +TGASRGIG +++Q A G + ++ A +KE+ E V I +K DS ++ Sbjct: 5 KSALVTGASRGIGRSIALQLAEEGYNVAVNYAGSKEKAEAVVEEIKAKGVDSFAIQANVA 64 Query: 352 DLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGT 531 D + +KEVV SL D +++NA R + E+ N+ G Sbjct: 65 DADEVKAMIKEVVSQFGSL------DVLVNNAGITRDNL-LMRMKEQEWDDVIDTNLKGV 117 Query: 532 ITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 711 + P ML + G + +SS G V PGQA Y A+K + G S EL ++GI Sbjct: 118 FNCIQKATPQMLRQRSGAIINLSSVVGAVGNPGQANYVATKAGVIGLTKSAARELASRGI 177 Query: 712 KVTVVCPGPIETPESSGATSSSQRHSSEKRVSVERCAELTIVAAT 846 V V PG I + + A S + ++ + R + T +A T Sbjct: 178 TVNAVAPGFI-VSDMTDALSDELKEQMLTQIPLARFGQDTDIANT 221
>Q6G9Y2:FABG_STAAS 3-oxoacyl-[acyl-carrier-protein] reductase - Staphylococcus aureus| (strain MSSA476) Length = 246 Score = 80.1 bits (196), Expect = 2e-14 Identities = 67/225 (29%), Positives = 103/225 (45%), Gaps = 2/225 (0%) Frame = +1 Query: 178 KVVWITGASRGIGEVLSMQFASLGAKLILS-ARNKEELERVKHNIMSKHPDS-KVEVLPM 351 K +TGASRGIG +++Q A G + ++ A +KE+ E V I +K DS ++ Sbjct: 5 KSALVTGASRGIGRSIALQLAEEGYNVAVNYAGSKEKAEAVVEEIKAKGVDSFAIQANVA 64 Query: 352 DLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGT 531 D + +KEVV SL D +++NA R + E+ N+ G Sbjct: 65 DADEVKAMIKEVVSQFGSL------DVLVNNAGITRDNL-LMRMKEQEWDDVIDTNLKGV 117 Query: 532 ITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 711 + P ML + G + +SS G V PGQA Y A+K + G S EL ++GI Sbjct: 118 FNCIQKATPQMLRQRSGAIINLSSVVGAVGNPGQANYVATKAGVIGLTKSAARELASRGI 177 Query: 712 KVTVVCPGPIETPESSGATSSSQRHSSEKRVSVERCAELTIVAAT 846 V V PG I + + A S + ++ + R + T +A T Sbjct: 178 TVNAVAPGFI-VSDMTDALSDELKEQMLTQIPLARFGQDTDIANT 221
>Q6GHK4:FABG_STAAR 3-oxoacyl-[acyl-carrier-protein] reductase - Staphylococcus aureus| (strain MRSA252) Length = 246 Score = 80.1 bits (196), Expect = 2e-14 Identities = 67/225 (29%), Positives = 103/225 (45%), Gaps = 2/225 (0%) Frame = +1 Query: 178 KVVWITGASRGIGEVLSMQFASLGAKLILS-ARNKEELERVKHNIMSKHPDS-KVEVLPM 351 K +TGASRGIG +++Q A G + ++ A +KE+ E V I +K DS ++ Sbjct: 5 KSALVTGASRGIGRSIALQLAEEGYNVAVNYAGSKEKAEAVVEEIKAKGVDSFAIQANVA 64 Query: 352 DLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGT 531 D + +KEVV SL D +++NA R + E+ N+ G Sbjct: 65 DADEVKAMIKEVVSQFGSL------DVLVNNAGITRDNL-LMRMKEQEWDDVIDTNLKGV 117 Query: 532 ITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 711 + P ML + G + +SS G V PGQA Y A+K + G S EL ++GI Sbjct: 118 FNCIQKATPQMLRQRSGAIINLSSVVGAVGNPGQANYVATKAGVIGLTKSAARELASRGI 177 Query: 712 KVTVVCPGPIETPESSGATSSSQRHSSEKRVSVERCAELTIVAAT 846 V V PG I + + A S + ++ + R + T +A T Sbjct: 178 TVNAVAPGFI-VSDMTDALSDELKEQMLTQIPLARFGQDTDIANT 221
>P99093:FABG_STAAN 3-oxoacyl-[acyl-carrier-protein] reductase - Staphylococcus aureus| (strain N315) Length = 246 Score = 80.1 bits (196), Expect = 2e-14 Identities = 67/225 (29%), Positives = 103/225 (45%), Gaps = 2/225 (0%) Frame = +1 Query: 178 KVVWITGASRGIGEVLSMQFASLGAKLILS-ARNKEELERVKHNIMSKHPDS-KVEVLPM 351 K +TGASRGIG +++Q A G + ++ A +KE+ E V I +K DS ++ Sbjct: 5 KSALVTGASRGIGRSIALQLAEEGYNVAVNYAGSKEKAEAVVEEIKAKGVDSFAIQANVA 64 Query: 352 DLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGT 531 D + +KEVV SL D +++NA R + E+ N+ G Sbjct: 65 DADEVKAMIKEVVSQFGSL------DVLVNNAGITRDNL-LMRMKEQEWDDVIDTNLKGV 117 Query: 532 ITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 711 + P ML + G + +SS G V PGQA Y A+K + G S EL ++GI Sbjct: 118 FNCIQKATPQMLRQRSGAIINLSSVVGAVGNPGQANYVATKAGVIGLTKSAARELASRGI 177 Query: 712 KVTVVCPGPIETPESSGATSSSQRHSSEKRVSVERCAELTIVAAT 846 V V PG I + + A S + ++ + R + T +A T Sbjct: 178 TVNAVAPGFI-VSDMTDALSDELKEQMLTQIPLARFGQDTDIANT 221
>P0A0H9:FABG_STAAM 3-oxoacyl-[acyl-carrier-protein] reductase - Staphylococcus aureus| (strain Mu50 / ATCC 700699) Length = 246 Score = 80.1 bits (196), Expect = 2e-14 Identities = 67/225 (29%), Positives = 103/225 (45%), Gaps = 2/225 (0%) Frame = +1 Query: 178 KVVWITGASRGIGEVLSMQFASLGAKLILS-ARNKEELERVKHNIMSKHPDS-KVEVLPM 351 K +TGASRGIG +++Q A G + ++ A +KE+ E V I +K DS ++ Sbjct: 5 KSALVTGASRGIGRSIALQLAEEGYNVAVNYAGSKEKAEAVVEEIKAKGVDSFAIQANVA 64 Query: 352 DLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGT 531 D + +KEVV SL D +++NA R + E+ N+ G Sbjct: 65 DADEVKAMIKEVVSQFGSL------DVLVNNAGITRDNL-LMRMKEQEWDDVIDTNLKGV 117 Query: 532 ITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 711 + P ML + G + +SS G V PGQA Y A+K + G S EL ++GI Sbjct: 118 FNCIQKATPQMLRQRSGAIINLSSVVGAVGNPGQANYVATKAGVIGLTKSAARELASRGI 177 Query: 712 KVTVVCPGPIETPESSGATSSSQRHSSEKRVSVERCAELTIVAAT 846 V V PG I + + A S + ++ + R + T +A T Sbjct: 178 TVNAVAPGFI-VSDMTDALSDELKEQMLTQIPLARFGQDTDIANT 221
>Q5HGK2:FABG_STAAC 3-oxoacyl-[acyl-carrier-protein] reductase - Staphylococcus aureus| (strain COL) Length = 246 Score = 80.1 bits (196), Expect = 2e-14 Identities = 67/225 (29%), Positives = 103/225 (45%), Gaps = 2/225 (0%) Frame = +1 Query: 178 KVVWITGASRGIGEVLSMQFASLGAKLILS-ARNKEELERVKHNIMSKHPDS-KVEVLPM 351 K +TGASRGIG +++Q A G + ++ A +KE+ E V I +K DS ++ Sbjct: 5 KSALVTGASRGIGRSIALQLAEEGYNVAVNYAGSKEKAEAVVEEIKAKGVDSFAIQANVA 64 Query: 352 DLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGT 531 D + +KEVV SL D +++NA R + E+ N+ G Sbjct: 65 DADEVKAMIKEVVSQFGSL------DVLVNNAGITRDNL-LMRMKEQEWDDVIDTNLKGV 117 Query: 532 ITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 711 + P ML + G + +SS G V PGQA Y A+K + G S EL ++GI Sbjct: 118 FNCIQKATPQMLRQRSGAIINLSSVVGAVGNPGQANYVATKAGVIGLTKSAARELASRGI 177 Query: 712 KVTVVCPGPIETPESSGATSSSQRHSSEKRVSVERCAELTIVAAT 846 V V PG I + + A S + ++ + R + T +A T Sbjct: 178 TVNAVAPGFI-VSDMTDALSDELKEQMLTQIPLARFGQDTDIANT 221
>Q5M875:DHB13_RAT 17-beta hydroxysteroid dehydrogenase 13 precursor - Rattus| norvegicus (Rat) Length = 300 Score = 80.1 bits (196), Expect = 2e-14 Identities = 62/201 (30%), Positives = 97/201 (48%), Gaps = 4/201 (1%) Frame = +1 Query: 157 RRDKVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKV 336 RR V G+ V ITGA GIG + + +FA ++L+L +K +E + + V Sbjct: 30 RRKSVAGQTVLITGAGHGIGRLTAYEFAKQKSRLVLWDISKHGVEETAAKC--RKLGAVV 87 Query: 337 EVLPMDLSSDEKSLKEVVHSAESLFSSAG-IDYMMHNAAFERPKRGALEETEEGLKATFK 513 V +D S+ E+ S + + G I+ +++NA P L +E + TF+ Sbjct: 88 HVFVVDCSNRA----EIYKSVDQVKKEVGDIEIVVNNAGAIYPA-DLLSTKDEEITKTFE 142 Query: 514 VNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSE 693 VN+ G + + L P ML R GH V ++S G P Y +SK A G+ +L +E Sbjct: 143 VNILGHFWIIKALLPSMLRRNSGHIVTVASVCGHRVIPYLIPYCSSKFAAVGFHRALTAE 202 Query: 694 LCT---KGIKVTVVCPGPIET 747 L T GIK + +CP + T Sbjct: 203 LDTLGKTGIKTSCLCPVFVNT 223
>Q9ASX2:TRNH1_ARATH Putative tropinone reductase homolog At1g07440 - Arabidopsis| thaliana (Mouse-ear cress) Length = 266 Score = 79.7 bits (195), Expect = 3e-14 Identities = 59/198 (29%), Positives = 89/198 (44%) Frame = +1 Query: 157 RRDKVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKV 336 +R + K V +TG ++GIG + +FA GA + ARN+ EL K Sbjct: 8 QRWSLKAKTVLVTGGTKGIGHAIVEEFAGFGAVIHTCARNEYELNECLSKWQKKGFQVTG 67 Query: 337 EVLPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKV 516 V L + + L + V S+F +D +++N R K L+ T E Sbjct: 68 SVCDASLRPEREKLMQTV---SSMFGGK-LDILINNLGAIRSKP-TLDYTAEDFSFHIST 122 Query: 517 NVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSEL 696 N+ L++L P + G G+ + MSS AG V ++YSA+K ALN +L E Sbjct: 123 NLESAYHLSQLAHPLLKASGCGNIIFMSSIAGVVSASVGSIYSATKGALNQLARNLACEW 182 Query: 697 CTKGIKVTVVCPGPIETP 750 + GI+ V P I TP Sbjct: 183 ASDGIRANAVAPAVIATP 200
>Q7Z5P4:DHB13_HUMAN 17-beta hydroxysteroid dehydrogenase 13 precursor - Homo sapiens| (Human) Length = 300 Score = 79.7 bits (195), Expect = 3e-14 Identities = 61/201 (30%), Positives = 92/201 (45%), Gaps = 4/201 (1%) Frame = +1 Query: 157 RRDKVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKV 336 RR V G++V ITGA GIG + +FA + L+L NK +E K+ Sbjct: 30 RRKSVAGEIVLITGAGHGIGRQTTYEFAKRQSILVLWDINKRGVEETAAECR------KL 83 Query: 337 EVLPMDLSSDEKSLKEVVHSAESLFSSAG-IDYMMHNAAFERPKRGALEETEEGLKATFK 513 V D + +E+ S + G + +++NA P L +E + TF+ Sbjct: 84 GVTAHAYVVDCSNREEIYRSLNQVKKEVGDVTIVVNNAGTVYPA-DLLSTKDEEITKTFE 142 Query: 514 VNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSE 693 VN+ G +T+ L P M++R GH V ++S G P Y +SK A G+ L SE Sbjct: 143 VNILGHFWITKALLPSMMERNHGHIVTVASVCGHEGIPYLIPYCSSKFAAVGFHRGLTSE 202 Query: 694 LCT---KGIKVTVVCPGPIET 747 L GIK + +CP + T Sbjct: 203 LQALGKTGIKTSCLCPVFVNT 223
>Q9BUT1:BDH2_HUMAN 3-hydroxybutyrate dehydrogenase type 2 - Homo sapiens (Human)| Length = 245 Score = 79.7 bits (195), Expect = 3e-14 Identities = 54/196 (27%), Positives = 96/196 (48%), Gaps = 1/196 (0%) Frame = +1 Query: 166 KVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVL 345 ++DGKV+ +T A++GIG+ ++ FA GAK+I + N+ +L+ + K+P + VL Sbjct: 3 RLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQE-----LEKYPGIQTRVL 57 Query: 346 PMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVF 525 + V + LF+ AG ++ H L+ E+ + +NV Sbjct: 58 DVTKKKQIDQFANEVERLDVLFNVAG--FVHHGT--------VLDCEEKDWDFSMNLNVR 107 Query: 526 GTITLTRLLAPFMLDRGMGHFVVMSSAAGKVP-TPGQALYSASKHALNGYFASLRSELCT 702 + + P ML + G+ + MSS A V + +YS +K A+ G S+ ++ Sbjct: 108 SMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQ 167 Query: 703 KGIKVTVVCPGPIETP 750 +GI+ VCPG ++TP Sbjct: 168 QGIRCNCVCPGTVDTP 183
>P0AG84:YGHA_ECOLI Uncharacterized oxidoreductase yghA - Escherichia coli| Length = 294 Score = 79.3 bits (194), Expect = 3e-14 Identities = 64/208 (30%), Positives = 96/208 (46%) Frame = +1 Query: 124 GDFTLLSCGRPRRDKVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKH 303 G+ T + GR + K +TG GIG ++ +A GA + +S EE + Sbjct: 37 GEKTYVGSGRLKDRKA-----LVTGGDSGIGRAAAIAYAREGADVAISYLPVEEEDAQDV 91 Query: 304 NIMSKHPDSKVEVLPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEE 483 + + K +LP DLS DEK + +VH A G+D M A + + Sbjct: 92 KKIIEECGRKAVLLPGDLS-DEKFARSLVHEAHKALG--GLDIMALVAGKQVAIPDIADL 148 Query: 484 TEEGLKATFKVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHAL 663 T E + TF +NVF LT+ P +L +G + SS P+P Y+A+K A+ Sbjct: 149 TSEQFQKTFAINVFALFWLTQEAIP-LLPKGAS-IITTSSIQAYQPSPHLLDYAATKAAI 206 Query: 664 NGYFASLRSELCTKGIKVTVVCPGPIET 747 Y L ++ KGI+V +V PGPI T Sbjct: 207 LNYSRGLAKQVAEKGIRVNIVAPGPIWT 234
>P0AG85:YGHA_ECO57 Uncharacterized oxidoreductase yghA - Escherichia coli O157:H7| Length = 294 Score = 79.3 bits (194), Expect = 3e-14 Identities = 64/208 (30%), Positives = 96/208 (46%) Frame = +1 Query: 124 GDFTLLSCGRPRRDKVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKH 303 G+ T + GR + K +TG GIG ++ +A GA + +S EE + Sbjct: 37 GEKTYVGSGRLKDRKA-----LVTGGDSGIGRAAAIAYAREGADVAISYLPVEEEDAQDV 91 Query: 304 NIMSKHPDSKVEVLPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEE 483 + + K +LP DLS DEK + +VH A G+D M A + + Sbjct: 92 KKIIEECGRKAVLLPGDLS-DEKFARSLVHEAHKALG--GLDIMALVAGKQVAIPDIADL 148 Query: 484 TEEGLKATFKVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHAL 663 T E + TF +NVF LT+ P +L +G + SS P+P Y+A+K A+ Sbjct: 149 TSEQFQKTFAINVFALFWLTQEAIP-LLPKGAS-IITTSSIQAYQPSPHLLDYAATKAAI 206 Query: 664 NGYFASLRSELCTKGIKVTVVCPGPIET 747 Y L ++ KGI+V +V PGPI T Sbjct: 207 LNYSRGLAKQVAEKGIRVNIVAPGPIWT 234
>Q6GV12:FVT1_MOUSE 3-ketodihydrosphingosine reductase precursor - Mus musculus (Mouse)| Length = 332 Score = 79.3 bits (194), Expect = 3e-14 Identities = 63/226 (27%), Positives = 109/226 (48%), Gaps = 3/226 (1%) Frame = +1 Query: 154 PRRDKVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSK 333 P+ + G V +TG S GIG+ ++++ GA + L ARN+++L + K +I + K Sbjct: 25 PKPLALPGAHVVVTGGSSGIGKCIAIECYKQGAFITLVARNEDKLLQAKKDIEKHSINDK 84 Query: 334 VEVL--PMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETE-EGLKA 504 VL +D+S D ++ V+ A+ +D +++ A G EE E + Sbjct: 85 QVVLCISVDVSQDYNQVENVIKQAQEKLGP--VDMLVNCAGTSMS--GKFEELEVSSFEK 140 Query: 505 TFKVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASL 684 +N G++ +R + M +R +G V +SS AG++ G YS+SK A+ G +L Sbjct: 141 LMSINYLGSVYPSRAVITTMKERRVGRIVFVSSQAGQLGLFGFTAYSSSKFAIRGLAEAL 200 Query: 685 RSELCTKGIKVTVVCPGPIETPESSGATSSSQRHSSEKRVSVERCA 822 + E+ + VTV P +TP G ++ E R+ E A Sbjct: 201 QMEVKPYNVYVTVAYPPDTDTP---GLAEENKTKPLETRLISETTA 243
>O70503:DHB12_MOUSE Estradiol 17-beta-dehydrogenase 12 - Mus musculus (Mouse)| Length = 312 Score = 79.3 bits (194), Expect = 3e-14 Identities = 53/194 (27%), Positives = 102/194 (52%), Gaps = 3/194 (1%) Frame = +1 Query: 175 GKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMD 354 G+ +TG + GIG+ + + A G K++L +R++++L +V +NI K + + + +D Sbjct: 50 GEWAVVTGGTDGIGKAYAEELAKRGMKIVLISRSQDKLNQVSNNIKEKF-NVETRTIAVD 108 Query: 355 LSSDEKSLKEVVHSAESLFSSAGIDYMMHNA--AFERPKRGA-LEETEEGLKATFKVNVF 525 S D+ + ++ S I +++N ++E P+ + + + +K +NV Sbjct: 109 FSLDD-----IYDKIKTGLSGLEIGVLVNNVGMSYEYPEYFLEIPDLDNTIKKLININVL 163 Query: 526 GTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTK 705 +TRL+ P M++R G + +SSA+G +P P +YSA+K ++ + L E +K Sbjct: 164 SVCKVTRLVLPGMVERSKGVILNISSASGMLPVPLLTIYSATKAFVDFFSQCLHEEYKSK 223 Query: 706 GIKVTVVCPGPIET 747 GI V V P + T Sbjct: 224 GIFVQSVMPYLVAT 237
>Q7M3I4:DHI1_RABIT Corticosteroid 11-beta-dehydrogenase isozyme 1 - Oryctolagus| cuniculus (Rabbit) Length = 292 Score = 79.0 bits (193), Expect = 4e-14 Identities = 61/199 (30%), Positives = 100/199 (50%), Gaps = 2/199 (1%) Frame = +1 Query: 157 RRDKVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKV 336 R + + GK V +TGAS+GIG+ ++ A +GA ++++AR+KE L+ V + + S Sbjct: 28 RPEMLQGKKVIVTGASKGIGKEIAFHLAKMGAHVVVTARSKETLQEVVAHCLKLGAASAH 87 Query: 337 EVLPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKV 516 + D ++ V A L G+D ++ N + ++ +V Sbjct: 88 YIA--GTMEDMTFAEQFVAKAGKLMG--GLDMLILNHITNASLMFFNNDIHH-VRKEMEV 142 Query: 517 NVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSE- 693 N + LT P ML + G VV+SS AGK+ P A YSASK AL+G+F+++R E Sbjct: 143 NFLSYVVLTVAALP-MLKQSNGSIVVVSSLAGKIAHPLIAPYSASKFALDGFFSAIRKEH 201 Query: 694 -LCTKGIKVTVVCPGPIET 747 L + +T+ G I+T Sbjct: 202 ALTNVNVSITLCVLGLIDT 220
>Q8VCC1:PGDH_MOUSE 15-hydroxyprostaglandin dehydrogenase [NAD+] - Mus musculus (Mouse)| Length = 269 Score = 78.6 bits (192), Expect = 6e-14 Identities = 56/199 (28%), Positives = 98/199 (49%), Gaps = 5/199 (2%) Frame = +1 Query: 169 VDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLP 348 V+GKV +TGA++GIG+ + GAK+ L N E + K + + K + Sbjct: 3 VNGKVALVTGAAQGIGKAFAEALLLHGAKVALVDWNLEAGVKCKAALDEQFEPQKTLFVQ 62 Query: 349 MDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFG 528 D+ +D+K L++ F +D +++NA E+ + T ++N+ Sbjct: 63 CDV-ADQKQLRDTFRKVVDHFGR--LDILVNNAGV---------NNEKNWEQTLQINLVS 110 Query: 529 TITLTRLLAPFMLDRGMGH---FVVMSSAAGKVPTPGQALYSASKHALNGY--FASLRSE 693 I+ T L +M + G + MSS AG +P Q +Y ASKH + G+ A++ + Sbjct: 111 VISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIIGFTRSAAMAAN 170 Query: 694 LCTKGIKVTVVCPGPIETP 750 L G+++ V+CPG ++TP Sbjct: 171 LMKSGVRLNVICPGFVDTP 189
>P73574:FABG1_SYNY3 3-oxoacyl-[acyl-carrier-protein] reductase 1 - Synechocystis sp.| (strain PCC 6803) Length = 247 Score = 78.6 bits (192), Expect = 6e-14 Identities = 55/191 (28%), Positives = 102/191 (53%), Gaps = 1/191 (0%) Frame = +1 Query: 178 KVVWITGASRGIGEVLSMQFASLGAKLILS-ARNKEELERVKHNIMSKHPDSKVEVLPMD 354 +V +TGASRGIG+ ++ A+ G K++++ A++ + V I++ ++ + V Sbjct: 7 QVALVTGASRGIGKATALALAATGMKVVVNYAQSSTAADAVVAEIIANGGEA-IAVQANV 65 Query: 355 LSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTI 534 ++DE + +++ + FS ID +++NA R L E +A +N+ G Sbjct: 66 ANADE--VDQLIKTTLDKFSR--IDVLVNNAGITRDTL-LLRMKLEDWQAVIDLNLTGVF 120 Query: 535 TLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 714 T+ ++ ML + G + ++S AG + PGQA YSA+K + G+ ++ EL ++G+ Sbjct: 121 LCTKAVSKLMLKQKSGRIINITSVAGMMGNPGQANYSAAKAGVIGFTKTVAKELASRGVT 180 Query: 715 VTVVCPGPIET 747 V V PG I T Sbjct: 181 VNAVAPGFIAT 191
>P16232:DHI1_RAT Corticosteroid 11-beta-dehydrogenase isozyme 1 - Rattus norvegicus| (Rat) Length = 288 Score = 78.6 bits (192), Expect = 6e-14 Identities = 62/209 (29%), Positives = 109/209 (52%), Gaps = 4/209 (1%) Frame = +1 Query: 157 RRDKVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKV 336 R + + GK V +TGAS+GIG ++ + +GA ++L+AR++E L++V + S Sbjct: 24 RPEMLQGKKVIVTGASKGIGREMAYHLSKMGAHVVLTARSEEGLQKVVSRCLELGAASAH 83 Query: 337 EVLPM--DLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATF 510 + D++ E+ VV + + L G+D ++ N + + ++ + Sbjct: 84 YIAGTMEDMAFAERF---VVEAGKLL---GGLDMLILNH-ITQTTMSLFHDDIHSVRRSM 136 Query: 511 KVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRS 690 +VN + L+ P ML + G ++SS AGK+ P A YSASK AL+G+F+++R Sbjct: 137 EVNFLSYVVLSTAALP-MLKQSNGSIAIISSMAGKMTQPLIASYSASKFALDGFFSTIRK 195 Query: 691 E-LCTK-GIKVTVVCPGPIETPESSGATS 771 E L TK + +T+ G I+T + TS Sbjct: 196 EHLMTKVNVSITLCVLGFIDTETALKETS 224
>Q9FZ42:GRDH1_ARATH Glucose and ribitol dehydrogenase homolog 1 - Arabidopsis thaliana| (Mouse-ear cress) Length = 288 Score = 78.2 bits (191), Expect = 8e-14 Identities = 69/236 (29%), Positives = 113/236 (47%), Gaps = 7/236 (2%) Frame = +1 Query: 163 DKVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMS----KHPDS 330 +K+ GKV ITG GIG + FAS GA + + +E + + + K DS Sbjct: 33 NKLRGKVALITGGDSGIGRAVGYCFASEGATVAFTYVKGQEEKDAQETLQMLKEVKTSDS 92 Query: 331 KVEV-LPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEG-LKA 504 K + +P DL DE + K VV + F ID +++NAA E+ + +EE +E L+ Sbjct: 93 KEPIAIPTDLGFDE-NCKRVVDEVVNAFGR--IDVLINNAA-EQYESSTIEEIDEPRLER 148 Query: 505 TFKVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQAL-YSASKHALNGYFAS 681 F+ N+F LTR M + G ++ +++ L Y+A+K A+ + Sbjct: 149 VFRTNIFSYFFLTRHALKHMKE---GSSIINTTSVNAYKGNASLLDYTATKGAIVAFTRG 205 Query: 682 LRSELCTKGIKVTVVCPGPIETPESSGATSSSQRHSSEKRVSVERCAELTIVAATH 849 L +L KGI+V V PGPI TP + + + + V ++R + VA ++ Sbjct: 206 LALQLAEKGIRVNGVAPGPIWTPLIPASFNEEKIKNFGSEVPMKRAGQPIEVAPSY 261
>P40397:YHXC_BACSU Uncharacterized oxidoreductase yhxC - Bacillus subtilis| Length = 285 Score = 77.8 bits (190), Expect = 1e-13 Identities = 67/231 (29%), Positives = 113/231 (48%), Gaps = 3/231 (1%) Frame = +1 Query: 166 KVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNK-EELERVKHNIMSKHPDSKVEV 342 K++GK ITG GIG +S+ FA GA +++ N+ ++ E K + + K + Sbjct: 38 KLEGKTAIITGGDSGIGRAVSVLFAKEGANVVIVYLNEHQDAEETKQYVEKE--GVKCLL 95 Query: 343 LPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNV 522 + D+ DE +VV A +F S ID +++NAA + + + T L TF+ N+ Sbjct: 96 IAGDVG-DEAFCNDVVGQASQVFPS--IDILVNNAAEQHVQPSIEKITSHQLIRTFQTNI 152 Query: 523 FGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQAL--YSASKHALNGYFASLRSEL 696 F LT+ + P L +G ++++A+ + L YSA+K A+ + SL L Sbjct: 153 FSMFYLTKAVLPH-LKKGSS---IINTASITAYKGNKTLIDYSATKGAIVTFTRSLSQSL 208 Query: 697 CTKGIKVTVVCPGPIETPESSGATSSSQRHSSEKRVSVERCAELTIVAATH 849 +GI+V V PGPI TP + ++ V +ER + VA ++ Sbjct: 209 VQQGIRVNAVAPGPIWTPLIPASFAAKDVEVFGSDVPMERPGQPVEVAPSY 259
>P38286:YB09_YEAST Uncharacterized oxidoreductase YBR159W - Saccharomyces cerevisiae| (Baker's yeast) Length = 347 Score = 77.8 bits (190), Expect = 1e-13 Identities = 59/194 (30%), Positives = 96/194 (49%), Gaps = 10/194 (5%) Frame = +1 Query: 175 GKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMD 354 GK ITGAS GIG+ + Q A G L+L +R + +LE ++ + +H V++L +D Sbjct: 62 GKYCAITGASDGIGKEFARQMAKRGFNLVLISRTQSKLEALQKELEDQH-HVVVKILAID 120 Query: 355 LSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEE-GLKATFKVNVFGT 531 ++ D++S E S + L + I +++N ETEE L+ +N T Sbjct: 121 IAEDKESNYE---SIKELCAQLPITVLVNNVGQSHSIPVPFLETEEKELRNIITINNTAT 177 Query: 532 ITLTRLLAPFMLDR---------GMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASL 684 + +T+++AP +++ G + M S G +PTP A YS SK L G+ SL Sbjct: 178 LLITQIIAPKIVETVKAENKKSGTRGLILTMGSFGGLIPTPLLATYSGSKSFLQGWSNSL 237 Query: 685 RSELCTKGIKVTVV 726 EL I V ++ Sbjct: 238 AGELSKDAIDVELI 251
>P50172:DHI1_MOUSE Corticosteroid 11-beta-dehydrogenase isozyme 1 - Mus musculus| (Mouse) Length = 292 Score = 77.8 bits (190), Expect = 1e-13 Identities = 58/199 (29%), Positives = 102/199 (51%), Gaps = 2/199 (1%) Frame = +1 Query: 157 RRDKVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKV 336 R + + GK V +TGAS+GIG ++ + +GA ++L+AR++E L++V + S Sbjct: 28 RPEMLQGKKVIVTGASKGIGREMAYHLSKMGAHVVLTARSEEGLQKVVSRCLELGAASAH 87 Query: 337 EVLPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKV 516 + D ++ + A L G+D ++ N + + ++ +V Sbjct: 88 YIA--GTMEDMTFAEQFIVKAGKLMG--GLDMLILNH-ITQTSLSLFHDDIHSVRRVMEV 142 Query: 517 NVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSEL 696 N + ++ P ML + G V+SS AGK+ P A YSASK AL+G+F+++R+EL Sbjct: 143 NFLSYVVMSTAALP-MLKQSNGSIAVISSLAGKMTQPMIAPYSASKFALDGFFSTIRTEL 201 Query: 697 -CTK-GIKVTVVCPGPIET 747 TK + +T+ G I+T Sbjct: 202 YITKVNVSITLCVLGLIDT 220
>Q5XG41:DH12A_XENLA Estradiol 17-beta-dehydrogenase 12-A - Xenopus laevis (African| clawed frog) Length = 318 Score = 77.8 bits (190), Expect = 1e-13 Identities = 55/194 (28%), Positives = 95/194 (48%), Gaps = 3/194 (1%) Frame = +1 Query: 175 GKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMD 354 GK +TGA+ GIG+ + + A G ++L +R+ E+L+ +KH +V Sbjct: 54 GKWAVVTGATDGIGKAYAEELARRGMSIVLISRSPEKLDEA-----AKHIKETFKVETKI 108 Query: 355 LSSDEKSLKEVVHSAESLFSSAGIDYMMHNA--AFERPKRGA-LEETEEGLKATFKVNVF 525 +++D E+ E+ I +++N ++E P+ + + E L +N+ Sbjct: 109 IAADFGKPTEIYERIEAGLRDLEIGVLVNNVGVSYEYPEYFLEIPDLENTLDKMININIM 168 Query: 526 GTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTK 705 +TRL+ P ML RG G + +SSA+G P P +YSA+K ++ + L +E K Sbjct: 169 SVCQMTRLVLPGMLGRGKGVILNISSASGMYPVPLLTVYSATKAFVDFFSRGLHAEYRNK 228 Query: 706 GIKVTVVCPGPIET 747 GI V V P + T Sbjct: 229 GINVQSVLPFYVAT 242
>P46331:YXBG_BACSU Uncharacterized oxidoreductase yxbG - Bacillus subtilis| Length = 273 Score = 77.4 bits (189), Expect = 1e-13 Identities = 56/212 (26%), Positives = 104/212 (49%), Gaps = 1/212 (0%) Frame = +1 Query: 166 KVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVL 345 +++ K ITGA+ GIG+ + FA+ GA++I+ NK+++E I + + E Sbjct: 3 RLENKTAVITGAATGIGQATAEVFANEGARVIIGDINKDQMEETVDAI--RKNGGQAESF 60 Query: 346 PMDLSSDEKSLKEVVHSAESLFSSAG-IDYMMHNAAFERPKRGALEETEEGLKATFKVNV 522 +D+ SDE S+K A+ + + G ID + +NA ++ E + V++ Sbjct: 61 HLDV-SDENSVKAF---ADQIKDACGTIDILFNNAGVDQEGGKVHEYPVDLFDRIIAVDL 116 Query: 523 FGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCT 702 GT ++ L P ML+ G G + SS +G+ ++ Y+A+K + ++ + Sbjct: 117 RGTFLCSKYLIPLMLENG-GSIINTSSMSGRAADLDRSGYNAAKGGITNLTKAMAIDYAR 175 Query: 703 KGIKVTVVCPGPIETPESSGATSSSQRHSSEK 798 GI+V + PG IETP + ++ E+ Sbjct: 176 NGIRVNSISPGTIETPLIDKLAGTKEQEMGEQ 207
>P40398:YHXD_BACSU Uncharacterized oxidoreductase yhxD - Bacillus subtilis| Length = 299 Score = 77.4 bits (189), Expect = 1e-13 Identities = 53/195 (27%), Positives = 97/195 (49%) Frame = +1 Query: 166 KVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVL 345 K+ G+ +TG GIG ++ +A GA + ++ +E+ + + + + K ++ Sbjct: 48 KLTGRKALVTGGDSGIGRAAAIAYAREGADVAINYLPEEQPDAEEVKELIEAEGRKAVLI 107 Query: 346 PMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVF 525 P DLS DE +++V +S G+D + A ++ + E + TF+VNVF Sbjct: 108 PGDLS-DESFCQDLVK--QSHHELGGLDVLALVAGKQQAVENIEDLPTEQIYKTFEVNVF 164 Query: 526 GTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTK 705 + + P++ + + +S G P+P Y+A+K+A+ G+ L +L +K Sbjct: 165 SLYWVVKAALPYLPEGAS--IITTTSVEGYNPSPMLLDYAATKNAIIGFTVGLGKQLASK 222 Query: 706 GIKVTVVCPGPIETP 750 GI+V V PGPI TP Sbjct: 223 GIRVNSVAPGPIWTP 237
>O07575:YHDF_BACSU Uncharacterized oxidoreductase yhdF - Bacillus subtilis| Length = 289 Score = 77.4 bits (189), Expect = 1e-13 Identities = 62/198 (31%), Positives = 95/198 (47%), Gaps = 3/198 (1%) Frame = +1 Query: 166 KVDGKVVWITGASRGIGEVLSMQFASLGAKL-ILSARNKEELERVKHNIMSKHPDSKVEV 342 K+ GKV ITG GIG ++ FA GA + IL + E + I ++ + + Sbjct: 42 KLKGKVAIITGGDSGIGRAAAIAFAKEGADISILYLDEHSDAEETRKRIEKENV--RCLL 99 Query: 343 LPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNV 522 +P D+ DE ++ V F +D +++NAA + P+ L + E L+ TF+ N+ Sbjct: 100 IPGDVG-DENHCEQAVQQTVDHFGK--LDILVNNAAEQHPQDSILNISTEQLEKTFRTNI 156 Query: 523 FGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQAL--YSASKHALNGYFASLRSEL 696 F +T+ P L G S A + T AL YS++K A+ + S+ L Sbjct: 157 FSMFHMTKKALPH-LQEGCAIINTTSITAYEGDT---ALIDYSSTKGAIVSFTRSMAKSL 212 Query: 697 CTKGIKVTVVCPGPIETP 750 KGI+V V PGPI TP Sbjct: 213 ADKGIRVNAVAPGPIWTP 230
>Q6P7R8:DHB12_RAT Estradiol 17-beta-dehydrogenase 12 - Rattus norvegicus (Rat)| Length = 312 Score = 77.4 bits (189), Expect = 1e-13 Identities = 52/189 (27%), Positives = 100/189 (52%), Gaps = 3/189 (1%) Frame = +1 Query: 175 GKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMD 354 G+ +TG + GIG+ + + A G K++L +R++++L+ V +NI K + + + +D Sbjct: 50 GEWAVVTGGTDGIGKSYAEELAKRGMKIVLISRSQDKLKEVSNNIKEKF-NVETRTIAVD 108 Query: 355 LSSDEKSLKEVVHSAESLFSSAGIDYMMHNA--AFERPKRGA-LEETEEGLKATFKVNVF 525 S D+ + ++ S I +++N ++E P+ + + + +K +NV Sbjct: 109 FSLDD-----IYDKIKTGLSGLEIGVLVNNVGMSYEYPEYFLEIPDLDNTIKKLININVL 163 Query: 526 GTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTK 705 +TRL+ P M++R G + +SSA+G +P P +YSA+K ++ + L E +K Sbjct: 164 SICKVTRLVLPGMVERSKGVILNISSASGMLPVPLLTVYSATKAFVDFFSQCLHEEYKSK 223 Query: 706 GIKVTVVCP 732 GI V V P Sbjct: 224 GIFVQSVLP 232
>O08699:PGDH_RAT 15-hydroxyprostaglandin dehydrogenase [NAD+] - Rattus norvegicus| (Rat) Length = 266 Score = 77.0 bits (188), Expect = 2e-13 Identities = 55/199 (27%), Positives = 98/199 (49%), Gaps = 5/199 (2%) Frame = +1 Query: 169 VDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLP 348 V+GKV +TGA++GIG+ + GAK+ L N E + K + + K + Sbjct: 3 VNGKVALVTGAAQGIGKAFTEALLLHGAKVALVDWNLETGVKCKAALDEQFEPQKTLFIQ 62 Query: 349 MDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFG 528 D+ +D+K L++ F +D +++NA E+ + T ++N+ Sbjct: 63 CDV-ADQKQLRDTFRKVVDHFGR--LDILVNNAGV---------NNEKNWEQTLQINLVS 110 Query: 529 TITLTRLLAPFMLDRGMGH---FVVMSSAAGKVPTPGQALYSASKHALNGY--FASLRSE 693 I+ T L +M + G + +SS AG +P Q +Y ASKH + G+ A++ + Sbjct: 111 VISGTYLGLDYMSKQNGGEGGIIINISSIAGLMPVAQQPVYCASKHGIIGFTRSAAMAAN 170 Query: 694 LCTKGIKVTVVCPGPIETP 750 L G+++ V+CPG ++TP Sbjct: 171 LMKSGVRLNVICPGFVKTP 189
>Q06136:FVT1_HUMAN 3-ketodihydrosphingosine reductase precursor - Homo sapiens (Human)| Length = 332 Score = 77.0 bits (188), Expect = 2e-13 Identities = 57/202 (28%), Positives = 100/202 (49%), Gaps = 3/202 (1%) Frame = +1 Query: 154 PRRDKVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSK 333 P+ + G V +TG S GIG+ ++++ GA + L ARN+++L + K I + K Sbjct: 25 PKPLALPGAHVVVTGGSSGIGKCIAIECYKQGAFITLVARNEDKLLQAKKEIEMHSINDK 84 Query: 334 VEVL--PMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEG-LKA 504 VL +D+S D ++ V+ A+ +D +++ A G E+ E + Sbjct: 85 QVVLCISVDVSQDYNQVENVIKQAQEKLGP--VDMLVNCAGMA--VSGKFEDLEVSTFER 140 Query: 505 TFKVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASL 684 +N G++ +R + M +R +G V +SS AG++ G YSASK A+ G +L Sbjct: 141 LMSINYLGSVYPSRAVITTMKERRVGRIVFVSSQAGQLGLFGFTAYSASKFAIRGLAEAL 200 Query: 685 RSELCTKGIKVTVVCPGPIETP 750 + E+ + +TV P +TP Sbjct: 201 QMEVKPYNVYITVAYPPDTDTP 222
>Q8AVY8:DH12B_XENLA Estradiol 17-beta-dehydrogenase 12-B - Xenopus laevis (African| clawed frog) Length = 318 Score = 77.0 bits (188), Expect = 2e-13 Identities = 56/189 (29%), Positives = 95/189 (50%), Gaps = 3/189 (1%) Frame = +1 Query: 175 GKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMD 354 GK +TGA+ GIG+ + + A G ++L +R+ E+LE +I K KVE Sbjct: 54 GKWAVVTGATDGIGKAYAEELARRGMNIVLISRSPEKLEEAAIHIKQKF---KVET--KI 108 Query: 355 LSSDEKSLKEVVHSAESLFSSAGIDYMMHNA--AFERPKRGA-LEETEEGLKATFKVNVF 525 +++D E+ E+ I +++N ++E P+ + + E L +N+ Sbjct: 109 IAADFGKPTEIYERIEAGLRDLEIGVLVNNVGISYEYPEYFLEIPDLENTLDKMININIM 168 Query: 526 GTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTK 705 +TRL+ P ML RG G + +SSA+G P P +YSA+K ++ + L +E +K Sbjct: 169 SVCQMTRLVLPGMLGRGKGVVLNISSASGMYPVPLLTVYSATKAFVDFFSRGLHAEYRSK 228 Query: 706 GIKVTVVCP 732 G+ V V P Sbjct: 229 GVTVQSVLP 237
>Q3T046:BDH2_BOVIN 3-hydroxybutyrate dehydrogenase type 2 - Bos taurus (Bovine)| Length = 245 Score = 76.6 bits (187), Expect = 2e-13 Identities = 61/253 (24%), Positives = 114/253 (45%), Gaps = 12/253 (4%) Frame = +1 Query: 166 KVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVL 345 ++DGKV+ +T A++GIG ++ FA GAK+I + N +L+ + K+P VL Sbjct: 3 RLDGKVIVLTAAAQGIGRAAALAFAKEGAKVIATDINDSKLQE-----LDKYPGIHTRVL 57 Query: 346 PMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVF 525 + + + LF+ AG ++ H + EET+ + +NV Sbjct: 58 DVTKKKQIDQFANDIERLDVLFNVAG--FVHHGTILD------CEETDWDF--SMNLNVR 107 Query: 526 GTITLTRLLAPFMLDRGMGHFVVMSSAAGKVP-TPGQALYSASKHALNGYFASLRSELCT 702 + + P M+ + G+ + MSS A + + +YS +K A+ G S+ ++ Sbjct: 108 SMYLMIKAFLPKMMAQKSGNIINMSSVASSIKGVVNRCVYSTTKAAVIGLTKSVAADFIQ 167 Query: 703 KGIKVTVVCPGPIETPE-----------SSGATSSSQRHSSEKRVSVERCAELTIVAATH 849 +GI+ VCPG ++TP + +R + + + E A L + A+ Sbjct: 168 QGIRCNCVCPGTVDTPSLQERIQARPNPEEALSDFLKRQKTGRFATAEEVALLCVYLASD 227 Query: 850 GLKEAWISYQPVL 888 + A+I+ PV+ Sbjct: 228 --ESAYITGNPVI 238
>Q56318:Y019_THEMA Uncharacterized oxidoreductase TM_0019 - Thermotoga maritima| Length = 256 Score = 76.3 bits (186), Expect = 3e-13 Identities = 63/202 (31%), Positives = 97/202 (48%), Gaps = 7/202 (3%) Frame = +1 Query: 169 VDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLP 348 ++GKV +TG +GIG ++ FA G K++++ ++E V+ M + V + Sbjct: 2 LEGKVAVVTGGGQGIGAAIAQLFAENGMKVVIAEIDEEA--GVEREEMLRERGLDVTFVK 59 Query: 349 MDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAA-------FERPKRGALEETEEGLKAT 507 D++ DE S+K +V ++ G+D +++NAA FERP LEE E Sbjct: 60 TDVA-DENSVKNMVRKTVEIYG--GVDVLVNNAAVMSVKSIFERP----LEEWER----V 108 Query: 508 FKVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLR 687 +VN+ G +R A M+ RG G + ++S P YSASK L SL Sbjct: 109 IRVNLTGPYICSRYCAEEMIKRGGGVIINIASTRAFQSEPDTEPYSASKGGLVALTHSLA 168 Query: 688 SELCTKGIKVTVVCPGPIETPE 753 L I+V + PG IET E Sbjct: 169 VSLSRYHIRVVSISPGWIETSE 190
>P72332:NODG_RHIS3 Nodulation protein G - Rhizobium sp. (strain N33)| Length = 245 Score = 76.3 bits (186), Expect = 3e-13 Identities = 56/194 (28%), Positives = 96/194 (49%) Frame = +1 Query: 166 KVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVL 345 ++ G+ +TGAS GIGE ++ + GA + L E+LE + + +V++ Sbjct: 3 ELTGRKALVTGASGGIGEAIARVLHAQGAIVGLHGTRVEKLETLAAEL-----GDRVKLF 57 Query: 346 PMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVF 525 P +LS+ ++ +K + AE+ G+D +++NA + + ++ +VN+ Sbjct: 58 PANLSNRDE-VKALGQKAEA--DLEGVDILVNNAGITKDGL-FVRMSDADWDTVLEVNLT 113 Query: 526 GTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTK 705 LTR L M+ R G + ++S G PGQ Y ASK + G+ SL E+ T+ Sbjct: 114 AVFRLTRELTHPMMRRRHGRIINITSVVGVTGNPGQTNYCASKAGMIGFSKSLAQEIATR 173 Query: 706 GIKVTVVCPGPIET 747 I V V PG IE+ Sbjct: 174 NITVNCVAPGFIES 187
>P39482:DHG1_BACME Glucose 1-dehydrogenase 1 - Bacillus megaterium| Length = 261 Score = 75.9 bits (185), Expect = 4e-13 Identities = 67/243 (27%), Positives = 113/243 (46%), Gaps = 8/243 (3%) Frame = +1 Query: 169 VDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEE-----LERVKHNIMSKHPDSK 333 ++GKVV ITG+S G+G+ ++++FA+ AK++++ R+KEE LE +K K Sbjct: 5 LEGKVVVITGSSTGLGKAMAIRFATEKAKVVVNYRSKEEEANSVLEEIK----------K 54 Query: 334 VEVLPMDLSSDEKSLKEVVHSAESLFSSAG-IDYMMHNAAFERPKRGALEETEEGLKATF 510 V + + D +V++ +S G +D M++NA E P + E + Sbjct: 55 VGGEAIAVKGDVTVESDVINLVQSSIKEFGKLDVMINNAGMENPV-SSHEMSLSDWNKVI 113 Query: 511 KVNVFGTITLTRLLAPFMLDRGM-GHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLR 687 N+ G +R + ++ + G + MSS K+P P Y+ASK + +L Sbjct: 114 DTNLTGAFLGSREAIKYFVENDIKGTVINMSSVHEKIPWPLFVHYAASKGGMKLMTETLA 173 Query: 688 SELCTKGIKVTVVCPGPIETP-ESSGATSSSQRHSSEKRVSVERCAELTIVAATHGLKEA 864 E KGI+V + PG I TP + QR E + + E +AA A Sbjct: 174 LEYAPKGIRVNNIGPGAINTPINAEKFADPEQRADVESMIPMGYIGEPEEIAAV----AA 229 Query: 865 WIS 873 W++ Sbjct: 230 WLA 232
>Q11150:Y484_MYCTU Uncharacterized oxidoreductase Rv0484c/MT0502 - Mycobacterium| tuberculosis Length = 251 Score = 75.5 bits (184), Expect = 5e-13 Identities = 55/196 (28%), Positives = 89/196 (45%), Gaps = 6/196 (3%) Frame = +1 Query: 178 KVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNI------MSKHPDSKVE 339 +V +TGAS GIGE + A+ G ++ AR + + + + I D+ VE Sbjct: 9 RVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVADVTDDAAVE 68 Query: 340 VLPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVN 519 L LS +D +++NA + + + E + + N Sbjct: 69 ALARALSR--------------------VDVLVNNAGGAKGLQFVADADLEHWRWMWDTN 108 Query: 520 VFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELC 699 V GT+ +TR L P ++D G G V ++S A G A Y+A+KHA +LR EL Sbjct: 109 VLGTLRVTRALLPKLIDSGDGLIVTVTSIAAIEVYDGGAGYTAAKHAQGALHRTLRGELL 168 Query: 700 TKGIKVTVVCPGPIET 747 K +++T + PG +ET Sbjct: 169 GKPVRLTEIAPGAVET 184
>Q3T0C2:PGDH_BOVIN 15-hydroxyprostaglandin dehydrogenase [NAD+] - Bos taurus (Bovine)| Length = 266 Score = 75.5 bits (184), Expect = 5e-13 Identities = 54/199 (27%), Positives = 96/199 (48%), Gaps = 5/199 (2%) Frame = +1 Query: 169 VDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLP 348 V+GKV +TGA++GIG + GAK+ L N E + K + + K + Sbjct: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVKCKAALDEQFEPQKTLFIQ 62 Query: 349 MDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFG 528 D+ +D++ L++ F +D +++NA E+ + T ++N+ Sbjct: 63 CDV-ADQEQLRDTFRKVVDHFGK--LDILVNNAGV---------NNEKNWEKTLQINLVS 110 Query: 529 TITLTRLLAPFMLDRGMGH---FVVMSSAAGKVPTPGQALYSASKHALNGY--FASLRSE 693 I+ T L +M + G + MSS AG +P Q +Y ASKH + G+ A++ + Sbjct: 111 VISGTYLGLDYMSKQNGGEGGININMSSLAGLMPVAQQPVYCASKHGIVGFTRSAAMAAN 170 Query: 694 LCTKGIKVTVVCPGPIETP 750 L G+++ +CPG ++TP Sbjct: 171 LMNSGVRLNAICPGFVDTP 189
>Q8CPI3:FABG_STAES 3-oxoacyl-[acyl-carrier-protein] reductase - Staphylococcus| epidermidis (strain ATCC 12228) Length = 244 Score = 75.5 bits (184), Expect = 5e-13 Identities = 62/224 (27%), Positives = 107/224 (47%), Gaps = 1/224 (0%) Frame = +1 Query: 178 KVVWITGASRGIGEVLSMQFASLGAKLILS-ARNKEELERVKHNIMSKHPDSKVEVLPMD 354 K +TGASRGIG +++Q A G + ++ A +K++ E V I +K +S + Sbjct: 3 KSALVTGASRGIGRSIALQLAEEGYNVAVNYAGSKDKAEAVVEEIKAKGVES-FAIQANV 61 Query: 355 LSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTI 534 DE +KE++ S F S +D +++NA + + E+ N+ G Sbjct: 62 AKGDE--VKEMIKEVVSQFGS--VDVLVNNAGITKDNL-LMRMKEQEWDDVIDTNLKGVF 116 Query: 535 TLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 714 + + P ML + G + ++S G + PGQA Y A+K + G + EL ++GI Sbjct: 117 NCIQKVTPQMLRQRSGAIINLTSIVGAMGNPGQANYVATKAGVIGLTKTAARELASRGIT 176 Query: 715 VTVVCPGPIETPESSGATSSSQRHSSEKRVSVERCAELTIVAAT 846 V V PG I + + A S + +++ ++R E T +A T Sbjct: 177 VNAVAPGFI-VSDMTNALSDDLKDQMLEQIPLKRFGEDTDIANT 219
>Q5HPW0:FABG_STAEQ 3-oxoacyl-[acyl-carrier-protein] reductase - Staphylococcus| epidermidis (strain ATCC 35984 / RP62A) Length = 244 Score = 75.5 bits (184), Expect = 5e-13 Identities = 62/224 (27%), Positives = 107/224 (47%), Gaps = 1/224 (0%) Frame = +1 Query: 178 KVVWITGASRGIGEVLSMQFASLGAKLILS-ARNKEELERVKHNIMSKHPDSKVEVLPMD 354 K +TGASRGIG +++Q A G + ++ A +K++ E V I +K +S + Sbjct: 3 KSALVTGASRGIGRSIALQLAEEGYNVAVNYAGSKDKAEAVVEEIKAKGVES-FAIQANV 61 Query: 355 LSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTI 534 DE +KE++ S F S +D +++NA + + E+ N+ G Sbjct: 62 AKGDE--VKEMIKEVVSQFGS--VDVLVNNAGITKDNL-LMRMKEQEWDDVIDTNLKGVF 116 Query: 535 TLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 714 + + P ML + G + ++S G + PGQA Y A+K + G + EL ++GI Sbjct: 117 NCIQKVTPQMLRQRSGAIINLTSIVGAMGNPGQANYVATKAGVIGLTKTAARELASRGIT 176 Query: 715 VTVVCPGPIETPESSGATSSSQRHSSEKRVSVERCAELTIVAAT 846 V V PG I + + A S + +++ ++R E T +A T Sbjct: 177 VNAVAPGFI-VSDMTNALSDDLKDQMLEQIPLKRFGEDTDIANT 219
>P43713:FABG_HAEIN 3-oxoacyl-[acyl-carrier-protein] reductase - Haemophilus influenzae| Length = 242 Score = 75.5 bits (184), Expect = 5e-13 Identities = 51/193 (26%), Positives = 95/193 (49%) Frame = +1 Query: 169 VDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLP 348 + GK+ +TG++RGIG ++ + +S GA +I +A +++ E + + K + V Sbjct: 1 MQGKIALVTGSTRGIGRAIAEELSSKGAFVIGTATSEKGAEAISAYLGDKGKGLVLNV-- 58 Query: 349 MDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFG 528 +D++S++ ++ ++ F ID +++NA R + EE + N+ Sbjct: 59 ----TDKESIETLLEQIKNDFGD--IDILVNNAGITRDNLLMRMKDEEWFDI-MQTNLTS 111 Query: 529 TITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKG 708 L++ + M+ + G + + S G PGQ Y A+K + G+ SL E+ +G Sbjct: 112 VYHLSKAMLRSMMKKRFGRIINIGSVVGSTGNPGQTNYCAAKAGVVGFSKSLAKEVAARG 171 Query: 709 IKVTVVCPGPIET 747 I V VV PG I T Sbjct: 172 ITVNVVAPGFIAT 184
>P51658:DHB2_MOUSE Estradiol 17-beta-dehydrogenase 2 - Mus musculus (Mouse)| Length = 381 Score = 75.5 bits (184), Expect = 5e-13 Identities = 59/194 (30%), Positives = 90/194 (46%), Gaps = 1/194 (0%) Frame = +1 Query: 169 VDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLP 348 VD K V +TGA G G L+ LG + +KE + + KH ++ VL Sbjct: 81 VDQKAVLVTGADSGFGHGLAKHLDKLGFTVFAGVLDKEGPGAEE---LRKHCSERLSVLQ 137 Query: 349 MDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAA-FERPKRGALEETEEGLKATFKVNVF 525 MD++ E+ +K+ G+ +++NA F P G L K VN F Sbjct: 138 MDVTKPEQ-IKDAHSKVTEKIQDKGLWAVVNNAGVFHLPIDGELIPMSIYRKC-MAVNFF 195 Query: 526 GTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTK 705 GT+ +T+ P +L + G V +SS G VP + Y+A+K AL + +R EL Sbjct: 196 GTVEVTKAFLP-LLRKSKGRLVNVSSMGGTVPLQMTSAYAATKAALTMFSTIIRQELDKW 254 Query: 706 GIKVTVVCPGPIET 747 G+KV + PG +T Sbjct: 255 GVKVVTIKPGGFKT 268
>P31808:YCIK_ECOLI Uncharacterized oxidoreductase yciK - Escherichia coli| Length = 252 Score = 75.1 bits (183), Expect = 6e-13 Identities = 57/210 (27%), Positives = 98/210 (46%), Gaps = 5/210 (2%) Frame = +1 Query: 151 RPRRDKVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDS 330 +P++D ++ +++ +TGAS GIG +M +A GA +IL RN+E+L +V +I ++ Sbjct: 4 QPKQDLLNDRIILVTGASDGIGREAAMTYARYGATVILLGRNEEKLRQVASHI-NEETGR 62 Query: 331 KVEVLPMDLSSDEKSLKEVVHSAESLFSSAGIDY-----MMHNAAFERPKRGALEETEEG 495 + + +DL L + + L ++Y ++HNA E+ + Sbjct: 63 QPQWFILDL------LTCTSENCQQLAQRIAVNYPRLDGVLHNAGLLGDVCPMSEQNPQV 116 Query: 496 LKATFKVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYF 675 + +VNV T LT+ L P +L G V SS+ G+ Y+ASK A G Sbjct: 117 WQDVMQVNVNATFMLTQALLPLLLKSDAGSLVFTSSSVGRQGRANWGAYAASKFATEGMM 176 Query: 676 ASLRSELCTKGIKVTVVCPGPIETPESSGA 765 L E + ++V + PG T + A Sbjct: 177 QVLADEY-QQRLRVNCINPGGTRTAMRASA 205
>Q08632:SDR1_PICAB Short-chain type dehydrogenase/reductase - Picea abies (Norway| spruce) (Picea excelsa) Length = 271 Score = 75.1 bits (183), Expect = 6e-13 Identities = 63/225 (28%), Positives = 101/225 (44%), Gaps = 3/225 (1%) Frame = +1 Query: 175 GKVVWITGASRGIGEVLSMQFASLGAKLILS-ARNKEELERVKHNIMSKHPDSKVEVLPM 351 G+V +TGASRGIG +++ A GAK+++ + N+ E V I +K P S V + Sbjct: 21 GRVAIVTGASRGIGREIALNMAEKGAKVVIHYSSNQHAAEEVASIINNKSPSSGDGVRAI 80 Query: 352 DLSSDEKSLKEVVHSAESLFSSAG-IDYMMHNAAFERPKRGALEET-EEGLKATFKVNVF 525 +D +V ++ + G + +++NA K L +T +E F+VN Sbjct: 81 VCKADVAEPSQVAQLFDTAEHAFGPLHIVVNNAGVTDSKYPTLAQTSDEEWDRIFQVNCK 140 Query: 526 GTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTK 705 G +R A ++ G G + +SS+ +P P Y+ASK A+ L EL Sbjct: 141 GAFLCSREAAKRVVRGGGGRIINISSSLVAMPIPRYGAYTASKAAVEMMTRILAQELRGT 200 Query: 706 GIKVTVVCPGPIETPESSGATSSSQRHSSEKRVSVERCAELTIVA 840 I V PGP+ T S + + K ER ++ VA Sbjct: 201 QITANCVAPGPVATDMFFAGKSEAAVEAGVKSNPFERLGKVEDVA 245
>P50941:FABG_RICPR 3-oxoacyl-[acyl-carrier-protein] reductase - Rickettsia prowazekii| Length = 241 Score = 75.1 bits (183), Expect = 6e-13 Identities = 57/210 (27%), Positives = 96/210 (45%) Frame = +1 Query: 175 GKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMD 354 GK ITGAS GIG ++ LG+K+I+S N+E+L+ + + + + +EV + Sbjct: 6 GKTSLITGASSGIGSAIARLLHKLGSKVIISGSNEEKLKSLGNALKDNYT---IEVCNLA 62 Query: 355 LSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTI 534 + +L + + L +AGI A+ ++ +N+ Sbjct: 63 NKEECSNLISKTSNLDILVCNAGIT----------SDTLAIRMKDQDFDKVIDINLKANF 112 Query: 535 TLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 714 L R M+ + G + +SS G PGQA Y ASK L G SL E+ T+GI Sbjct: 113 ILNREAIKKMIQKRYGRIINISSIVGIAGNPGQANYCASKAGLIGMTKSLSYEVATRGIT 172 Query: 715 VTVVCPGPIETPESSGATSSSQRHSSEKRV 804 V V PG I++ + + + QR + +++ Sbjct: 173 VNAVAPGFIKS-DMTDKLNEKQREAIVQKI 201
>Q6QA33:DH12B_DANRE Estradiol 17-beta-dehydrogenase 12-B - Danio rerio (Zebrafish)| (Brachydanio rerio) Length = 311 Score = 75.1 bits (183), Expect = 6e-13 Identities = 57/207 (27%), Positives = 105/207 (50%), Gaps = 3/207 (1%) Frame = +1 Query: 136 LLSCGRPRRDKVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMS 315 +L G R GK +TGA+ GIG+ + + A G ++L +R +E+L+ V S Sbjct: 35 ILGNGNLMRASSLGKWAVVTGATDGIGKAYAEELARRGFAIVLISRTQEKLDEV-----S 89 Query: 316 KHPDSKVEVLPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNA--AFERPKRGA-LEET 486 K +SK +V +S+D S+ ++ ES + I +++N ++ P+ + + Sbjct: 90 KAIESKYKVETKTISADFGSV-DIYPKIESGLAGLEIGVLVNNVGVSYSYPEFFLNIPDV 148 Query: 487 EEGLKATFKVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALN 666 + + +N+ +TRL+ P M+DR G + ++SA+G P P LYS++K ++ Sbjct: 149 DSFINNMININIMSVCQMTRLVLPRMVDRSKGVILNVASASGMYPVPLLTLYSSTKAFVD 208 Query: 667 GYFASLRSELCTKGIKVTVVCPGPIET 747 + L +E +KGI + V P + T Sbjct: 209 FFSRGLDAEYKSKGIIIQSVLPFYVTT 235
>P50162:TRN1_DATST Tropinone reductase 1 - Datura stramonium (Jimsonweed) (Common| thornapple) Length = 273 Score = 74.7 bits (182), Expect = 8e-13 Identities = 61/224 (27%), Positives = 100/224 (44%), Gaps = 3/224 (1%) Frame = +1 Query: 133 TLLSCGRPRRDKVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIM 312 ++++C R + G +TG S+GIG + + A LGA++ +RN++EL+ + Sbjct: 7 SMMNCNNEGRWSLKGTTALVTGGSKGIGYAIVEELAGLGARVYTCSRNEKELDECLE--I 64 Query: 313 SKHPDSKVEVLPMDLSSD---EKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEE 483 + VE DL S +K ++ V H + ++ +++NA K A + Sbjct: 65 WREKGLNVEGSVCDLLSRTERDKLMQTVAHVFDGK-----LNILVNNAGVVIHKE-AKDF 118 Query: 484 TEEGLKATFKVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHAL 663 TE+ N L+++ P + G+ + +SS AG P +LYSASK A+ Sbjct: 119 TEKDYNIIMGTNFEAAYHLSQIAYPLLKASQNGNVIFLSSIAGFSALPSVSLYSASKGAI 178 Query: 664 NGYFASLRSELCTKGIKVTVVCPGPIETPESSGATSSSQRHSSE 795 N SL E I+V V PG I TP A + E Sbjct: 179 NQMTKSLACEWAKDNIRVNSVAPGVILTPLVETAIKKNPHQKEE 222
>Q8MJY8:PGDH_MACFA 15-hydroxyprostaglandin dehydrogenase [NAD+] - Macaca fascicularis| (Crab eating macaque) (Cynomolgus monkey) Length = 266 Score = 74.7 bits (182), Expect = 8e-13 Identities = 55/198 (27%), Positives = 94/198 (47%), Gaps = 5/198 (2%) Frame = +1 Query: 169 VDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLP 348 V+GKV +TGA++GIG + GAK+ L N E + K + K K + Sbjct: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEKFEPQKTLFIQ 62 Query: 349 MDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFG 528 D+ +D++ L++ F +D +++NA E+ + T ++N+ Sbjct: 63 CDV-ADQQQLRDTFRKVVDHFGR--LDILVNNAGV---------NNEKNWEKTLQINLVS 110 Query: 529 TITLTRLLAPFMLDRGMGH---FVVMSSAAGKVPTPGQALYSASKHALNGY--FASLRSE 693 I+ T L +M + G + MSS AG +P Q +Y ASKH + G+ A+L + Sbjct: 111 VISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAAN 170 Query: 694 LCTKGIKVTVVCPGPIET 747 L G+++ +CPG + T Sbjct: 171 LMNSGVRLNAICPGFVNT 188
>Q8JZV9:BDH2_MOUSE 3-hydroxybutyrate dehydrogenase type 2 - Mus musculus (Mouse)| Length = 245 Score = 74.7 bits (182), Expect = 8e-13 Identities = 60/253 (23%), Positives = 113/253 (44%), Gaps = 12/253 (4%) Frame = +1 Query: 166 KVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVL 345 ++DGKV+ +T A++GIG ++ FA GAK+I + N+ +L+ + + + VL Sbjct: 3 RLDGKVIVLTAAAQGIGRASALAFAREGAKVIATDINESKLQE-----LESYRGIQTRVL 57 Query: 346 PMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVF 525 + + + LF+ AG +H+ L+ E+ + +NV Sbjct: 58 DVTKKRQIDQFASEIERIDVLFNVAG---FVHHGTI-------LDCEEKDWDFSMNLNVR 107 Query: 526 GTITLTRLLAPFMLDRGMGHFVVMSSAAGKVP-TPGQALYSASKHALNGYFASLRSELCT 702 + + P ML + G+ + MSS A + + +YSA+K A+ G S+ ++ Sbjct: 108 SMFLMIKAFLPKMLAQKSGNIINMSSVASSIKGVENRCVYSATKAAVIGLTKSVAADFIQ 167 Query: 703 KGIKVTVVCPGPIETPE-----------SSGATSSSQRHSSEKRVSVERCAELTIVAATH 849 +GI+ VCPG ++TP + R + + S E A L + A+ Sbjct: 168 QGIRCNCVCPGTVDTPSLQERIQARDNPKEALKTFLNRQKTGRFASAEEVALLCVYLASD 227 Query: 850 GLKEAWISYQPVL 888 + A+++ PV+ Sbjct: 228 --ESAYVTGNPVI 238
>P66782:Y1385_MYCBO Uncharacterized oxidoreductase Mb1385 - Mycobacterium bovis| Length = 247 Score = 74.3 bits (181), Expect = 1e-12 Identities = 57/193 (29%), Positives = 91/193 (47%) Frame = +1 Query: 169 VDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLP 348 ++ + ITG ++G+G + +F + GA+++L N E E + D + Sbjct: 5 LNARTAVITGGAQGLGLAIGQRFVAEGARVVLGDVNLEATEVAAKRLGG---DDVALAVR 61 Query: 349 MDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFG 528 D++ + + ++ +A F G+D M++NA R TEE V++ G Sbjct: 62 CDVTQAD-DVDILIRTAVERFG--GLDVMVNNAGITRDAT-MRTMTEEQFDQVIAVHLKG 117 Query: 529 TITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKG 708 T TRL A M +R G V MSS +GKV GQ YSA+K + G + EL G Sbjct: 118 TWNGTRLAAAIMRERKRGAIVNMSSVSGKVGMVGQTNYSAAKAGIVGMTKAAAKELAHLG 177 Query: 709 IKVTVVCPGPIET 747 I+V + PG I + Sbjct: 178 IRVNAIAPGLIRS 190
>P66781:Y1350_MYCTU Uncharacterized oxidoreductase Rv1350/MT1393 - Mycobacterium| tuberculosis Length = 247 Score = 74.3 bits (181), Expect = 1e-12 Identities = 57/193 (29%), Positives = 91/193 (47%) Frame = +1 Query: 169 VDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLP 348 ++ + ITG ++G+G + +F + GA+++L N E E + D + Sbjct: 5 LNARTAVITGGAQGLGLAIGQRFVAEGARVVLGDVNLEATEVAAKRLGG---DDVALAVR 61 Query: 349 MDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFG 528 D++ + + ++ +A F G+D M++NA R TEE V++ G Sbjct: 62 CDVTQAD-DVDILIRTAVERFG--GLDVMVNNAGITRDAT-MRTMTEEQFDQVIAVHLKG 117 Query: 529 TITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKG 708 T TRL A M +R G V MSS +GKV GQ YSA+K + G + EL G Sbjct: 118 TWNGTRLAAAIMRERKRGAIVNMSSVSGKVGMVGQTNYSAAKAGIVGMTKAAAKELAHLG 177 Query: 709 IKVTVVCPGPIET 747 I+V + PG I + Sbjct: 178 IRVNAIAPGLIRS 190
>P50165:TRNH_DATST Tropinone reductase homolog - Datura stramonium (Jimsonweed)| (Common thornapple) Length = 268 Score = 74.3 bits (181), Expect = 1e-12 Identities = 65/236 (27%), Positives = 104/236 (44%), Gaps = 4/236 (1%) Frame = +1 Query: 148 GRPRRDKVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPD 327 G RR + G +TG +RGIG + + A+ GA++ +R++ +L+ K Sbjct: 8 GGDRRWSLRGMTALVTGGTRGIGYAIVEELANFGAEVYTCSRSQNDLDECLEKWRRKGFK 67 Query: 328 SKVEVLPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKAT 507 V + S ++L E V S+ + ++ +++NA PK A T E Sbjct: 68 VSGPVCDVSSISQRQTLMESVTSS----FNGKLNILINNAGTTIPKE-ATNFTAEDYSII 122 Query: 508 FKVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLR 687 N + L +L P + G V SSAAG + P ++Y+ASK A+N SL Sbjct: 123 MGTNFEASYNLCQLAHPLLKASGNASIVFNSSAAGVIAVPLSSIYAASKGAINQVTKSLA 182 Query: 688 SELCTKGIKVTVVCPGPIETPESSGATS-SSQRHSSEK---RVSVERCAELTIVAA 843 E I+V V P I TP A SQ+ + E R ++R E + V++ Sbjct: 183 CEWAKDSIRVNAVAPWIINTPIIEAACQVPSQKKNIESLIGRAPMKRAGEPSEVSS 238
>Q75KH3:GRDH_ORYSJ Glucose and ribitol dehydrogenase homolog - Oryza sativa subsp.| japonica (Rice) Length = 300 Score = 74.3 bits (181), Expect = 1e-12 Identities = 60/238 (25%), Positives = 113/238 (47%), Gaps = 12/238 (5%) Frame = +1 Query: 163 DKVDGKVVWITGASRGIGEVLSMQFASLGAKLILS------ARNKEELERVKHNIMSKHP 324 +K+ KV +TG GIG + + FA GA + + ++ EE R +I ++ Sbjct: 36 NKLKDKVAIVTGGDSGIGRAVCLCFALEGATVAFTYVKGQEEKDAEETLRALRDIRARTG 95 Query: 325 DSKVEVLPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKA 504 +P DL D+ + ++VV + A ID +++NAA + + + TE+ L+ Sbjct: 96 AKDPMAIPADLGYDD-NCRKVVDEVAGAYGGA-IDILVNNAAEQYERPSITDITEDDLER 153 Query: 505 TFKVNVFGTITLTRLLAPFMLDR----GMGHFVVMSSAAGKVPTPGQAL--YSASKHALN 666 F+ N+F +++ M DR G G ++++++ + L Y+A+K A+ Sbjct: 154 VFRTNIFSYFFMSKHAVKRMRDRRGGAGAGGCSIINTSSINAYKGNKTLLDYTATKGAIV 213 Query: 667 GYFASLRSELCTKGIKVTVVCPGPIETPESSGATSSSQRHSSEKRVSVERCAELTIVA 840 + +L +L +GI+V V PGPI TP + + + +V + R + + VA Sbjct: 214 AFTRALALQLAEEGIRVNGVAPGPIWTPLIPASFAEEKVRQFGSQVPMGRAGQPSEVA 271
>P40288:DHG_BACME Glucose 1-dehydrogenase - Bacillus megaterium| Length = 261 Score = 74.3 bits (181), Expect = 1e-12 Identities = 66/243 (27%), Positives = 113/243 (46%), Gaps = 8/243 (3%) Frame = +1 Query: 169 VDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEE-----LERVKHNIMSKHPDSK 333 ++GKVV ITG+S G+G+ ++++FA+ AK++++ R+KE+ LE +K K Sbjct: 5 LEGKVVVITGSSTGLGKSMAIRFATEKAKVVVNYRSKEDEANSVLEEIK----------K 54 Query: 334 VEVLPMDLSSDEKSLKEVVHSAESLFSSAG-IDYMMHNAAFERPKRGALEETEEGLKATF 510 V + + D +V++ +S G +D M++NA E P + E + Sbjct: 55 VGGEAIAVKGDVTVESDVINLVQSAIKEFGKLDVMINNAGLENPV-SSHEMSLSDWNKVI 113 Query: 511 KVNVFGTITLTRLLAPFMLDRGM-GHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLR 687 N+ G +R + ++ + G + MSS K+P P Y+ASK + +L Sbjct: 114 DTNLTGAFLGSREAIKYFVENDIKGTVINMSSVHEKIPWPLFVHYAASKGGMKLMTETLA 173 Query: 688 SELCTKGIKVTVVCPGPIETP-ESSGATSSSQRHSSEKRVSVERCAELTIVAATHGLKEA 864 E KGI+V + PG I TP + QR E + + E +AA A Sbjct: 174 LEYAPKGIRVNNIGPGAINTPINAEKFADPEQRADVESMIPMGYIGEPEEIAAV----AA 229 Query: 865 WIS 873 W++ Sbjct: 230 WLA 232
>P06234:NODG_RHIME Nodulation protein G - Rhizobium meliloti (Sinorhizobium meliloti)| Length = 245 Score = 73.9 bits (180), Expect = 1e-12 Identities = 57/215 (26%), Positives = 103/215 (47%) Frame = +1 Query: 166 KVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVL 345 ++ G+ +TGAS IG ++ + GA + L E+LE + + +V++ Sbjct: 3 ELTGRKALVTGASGAIGGAIARVLHAQGAIVGLHGTQIEKLETLATEL-----GDRVKLF 57 Query: 346 PMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVF 525 P +L++ ++ +K + AE+ G+D +++NA + L + +VN+ Sbjct: 58 PANLANRDE-VKALGQRAEA--DLEGVDILVNNAGITKDGL-FLHMADPDWDIVLEVNLT 113 Query: 526 GTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTK 705 LTR + M+ R G + ++S AG + PGQ Y ASK + G+ SL E+ T+ Sbjct: 114 AMFRLTREITQQMIRRRNGRIINVTSVAGAIGNPGQTNYCASKAGMIGFSKSLAQEIATR 173 Query: 706 GIKVTVVCPGPIETPESSGATSSSQRHSSEKRVSV 810 I V V PG IE+ A + H ++++ V Sbjct: 174 NITVNCVAPGFIES-----AMTDKLNHKQKEKIMV 203
>Q68VY7:FABG_RICTY 3-oxoacyl-[acyl-carrier-protein] reductase - Rickettsia typhi| Length = 241 Score = 73.9 bits (180), Expect = 1e-12 Identities = 56/210 (26%), Positives = 97/210 (46%) Frame = +1 Query: 175 GKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMD 354 GK ITGAS GIG ++ LG+K+I+S N+++L+ + + + + +EV + Sbjct: 6 GKTSLITGASGGIGSAIARLLHKLGSKVIISGSNEKKLKLLGNTLKDNYI---IEVCNLA 62 Query: 355 LSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTI 534 + +L + + + L +AGI A+ ++ +N+ Sbjct: 63 NKEECNNLISKISNLDILVCNAGIT----------SDTLAIRMKDQDFDKVIDINLKANF 112 Query: 535 TLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 714 L R M+ + G + +SS G PGQA Y ASK L G SL E+ T+GI Sbjct: 113 ILNREAIKKMIQKRYGRIINISSIVGIAGNPGQANYCASKAGLIGMTKSLSYEVATRGIT 172 Query: 715 VTVVCPGPIETPESSGATSSSQRHSSEKRV 804 V V PG I++ + + + QR + +++ Sbjct: 173 VNAVAPGFIKS-DMTDKLNEKQREAIVQKI 201
>P16542:DHK1_STRVN Granaticin polyketide synthase putative ketoacyl reductase 1 -| Streptomyces violaceoruber Length = 272 Score = 73.9 bits (180), Expect = 1e-12 Identities = 59/193 (30%), Positives = 93/193 (48%), Gaps = 3/193 (1%) Frame = +1 Query: 181 VVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLS 360 V +TGA+ GIG ++ + A+LGA+ L AR++E L + + + D V + Sbjct: 19 VALVTGATSGIGLAIARRLAALGARTFLCARDEERLAQTVKELRGEGFDVDGTVCDV--- 75 Query: 361 SDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKA-TFKVNVFGTIT 537 +D ++ V +A + + +D +++NA R GA E + L N+ Sbjct: 76 ADPAQIRAYVAAAVQRYGT--VDILVNNAG--RSGGGATAEIADELWLDVITTNLTSVFL 131 Query: 538 LTR--LLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 711 +T+ L A ML + G + ++S GK YSASKH + G +L EL GI Sbjct: 132 MTKEVLNAGGMLAKKRGRIINIASTGGKQGVVHAVPYSASKHGVVGLTKALGLELARTGI 191 Query: 712 KVTVVCPGPIETP 750 V VCPG +ETP Sbjct: 192 TVNAVCPGFVETP 204
>Q51977:CMTB_PSEPU 2,3-dihydroxy-2,3-dihydro-p-cumate dehydrogenase - Pseudomonas| putida Length = 259 Score = 73.9 bits (180), Expect = 1e-12 Identities = 55/193 (28%), Positives = 94/193 (48%) Frame = +1 Query: 169 VDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLP 348 ++G+V +TG + GIG + + LGA++ S ++ L + + +KH D+ + V Sbjct: 11 LEGQVAVVTGGAHGIGLGIVERLLGLGARVTASDIDESGLSLLCERLAAKHADA-IAVHA 69 Query: 349 MDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFG 528 DL S+E+ + + +A F S I + N A R LE T E LKAT N++ Sbjct: 70 ADL-SEEQGAQGLHRAAVERFGSVQI---LVNCAGGGVIRPFLEHTPETLKATIDRNLWT 125 Query: 529 TITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKG 708 + +R+ P ML R G + + + + + P A Y+A+K ++G L E +G Sbjct: 126 ALWCSRVFLPDMLARQYGRIINIGADSVRNGLPDHAAYNAAKGGMHGLTTGLAREFARQG 185 Query: 709 IKVTVVCPGPIET 747 + V V P + T Sbjct: 186 VTVNTVAPCAVNT 198
>Q9KWN1:SDH_AGRTU Serine 3-dehydrogenase - Agrobacterium tumefaciens| Length = 249 Score = 73.6 bits (179), Expect = 2e-12 Identities = 62/245 (25%), Positives = 106/245 (43%) Frame = +1 Query: 184 VWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSS 363 + ITGA+ G G+ + +F G K+I + R E LE + + S ++ + Sbjct: 5 ILITGATSGFGQATAQRFVKEGWKVIGTGRRAERLEALSAELGSAFHGVAFDI------T 58 Query: 364 DEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLT 543 DE++ K+ + F ID +++NA A + + + N+ G + +T Sbjct: 59 DEEATKKALAGLPDGFRD--IDILVNNAGLALGTAPAPQVPLKDWQTMVDTNITGLLNVT 116 Query: 544 RLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIKVTV 723 L P +++R G + +SS A P G +Y +K L + LRS+L KG++VT Sbjct: 117 HHLLPTLIER-KGIVINLSSVAAHYPYLGGNVYGGTKAFLRQFSLGLRSDLHGKGVRVTS 175 Query: 724 VCPGPIETPESSGATSSSQRHSSEKRVSVERCAELTIVAATHGLKEAWISYQPVLAVMYV 903 + PG ET + T +Q S V I H W++ QP + Sbjct: 176 IEPGMCETEFTLVRTGGNQEASDNLYKGVNPITADDIANTIH-----WVASQPKHININS 230 Query: 904 VQYMP 918 ++ MP Sbjct: 231 LELMP 235
>Q92GE0:FABG_RICCN 3-oxoacyl-[acyl-carrier-protein] reductase - Rickettsia conorii| Length = 241 Score = 73.6 bits (179), Expect = 2e-12 Identities = 58/210 (27%), Positives = 97/210 (46%) Frame = +1 Query: 175 GKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMD 354 GK ITGAS GIG ++ LG+ +I+S N+E+L+ + + + +EV + Sbjct: 6 GKTSLITGASGGIGGAIARLLHKLGSHVIISGSNEEKLQSLGKVVKDNYT---IEVCNL- 61 Query: 355 LSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTI 534 +D++ + ++ A L D ++ NA A+ +E +N+ Sbjct: 62 --ADKEECRNLISKASKL------DILVCNAGITSDTL-AIRMKDEDFDKVIDINLKANF 112 Query: 535 TLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 714 L R M+ G + +SS G PGQA Y ASK L G SL E+ T+GI Sbjct: 113 ILNREAIKKMIQNRYGRIINISSIVGISGNPGQANYCASKAGLIGMTKSLSYEVATRGIT 172 Query: 715 VTVVCPGPIETPESSGATSSSQRHSSEKRV 804 V V PG I++ + + + QR + +++ Sbjct: 173 VNTVAPGFIKS-DMTDKLNEKQREAIVQKI 201
>P28643:FABG_CUPLA 3-oxoacyl-[acyl-carrier-protein] reductase, chloroplast precursor -| Cuphea lanceolata Length = 320 Score = 73.6 bits (179), Expect = 2e-12 Identities = 54/199 (27%), Positives = 101/199 (50%), Gaps = 2/199 (1%) Frame = +1 Query: 169 VDGKVVWITGASRGIGEVLSMQFASLGAKLILS-ARNKEELERVKHNIMSKHPDSKVEVL 345 V+ VV +TGASRGIG+ +++ G K++++ AR+ +E E V I + + Sbjct: 75 VESPVVIVTGASRGIGKAIALSLGKAGCKVLVNYARSSKEAEEVSKEIEAF--GGQALTF 132 Query: 346 PMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGL-KATFKVNV 522 D+S +E ++ ++ +A + + +D +++NA R G L ++ + +N+ Sbjct: 133 GGDVSKEE-DVEAMIKTAVDAWGT--VDILVNNAGITRD--GLLMRMKKSQWQEVIDLNL 187 Query: 523 FGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCT 702 G T+ A M+ + G + ++S G V GQA YSA+K + G+ ++ E + Sbjct: 188 TGVFLCTQAAAKIMMKKKKGRIINIASVVGLVGNAGQANYSAAKAGVIGFTKTVAREYAS 247 Query: 703 KGIKVTVVCPGPIETPESS 759 + I V V PG I + +S Sbjct: 248 RNINVNAVAPGFISSDMTS 266
>P07999:DHGB_BACME Glucose 1-dehydrogenase B - Bacillus megaterium| Length = 262 Score = 73.6 bits (179), Expect = 2e-12 Identities = 65/240 (27%), Positives = 113/240 (47%), Gaps = 4/240 (1%) Frame = +1 Query: 169 VDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLP 348 ++GKVV ITG+S G+G+ ++++FA+ AK++++ R+KE+ + N + + KV Sbjct: 5 LEGKVVVITGSSTGLGKSMAIRFATEKAKVVVNYRSKED----EANSVLEEEIKKVGGEA 60 Query: 349 MDLSSDEKSLKEVVHSAESLFSSAG-IDYMMHNAAFERPKRGALEETEEGLKATFKVNVF 525 + + D +V++ +S G +D M++NA E P + E + N+ Sbjct: 61 IAVKGDVTVESDVINLVQSAIKEFGKLDVMINNAGMENPV-SSHEMSLSDWNKVIDTNLT 119 Query: 526 GTITLTRLLAPFMLDRGM-GHFVVMSSA-AGKVPTPGQALYSASKHALNGYFASLRSELC 699 G +R + ++ + G + MSS K+P P Y+ASK + +L E Sbjct: 120 GAFLGSREAIKYFVENDIKGTVINMSSVHEWKIPWPLFVHYAASKGGMKLMTETLALEYA 179 Query: 700 TKGIKVTVVCPGPIETP-ESSGATSSSQRHSSEKRVSVERCAELTIVAATHGLKEAWISY 876 KGI+V + PG I TP + QR E + + E +AA L + SY Sbjct: 180 PKGIRVNNIGPGAINTPINAEKFADPEQRADVESMIPMGYIGEPEEIAAVAWLASSEASY 239
>Q5E9H7:DHB12_BOVIN Estradiol 17-beta-dehydrogenase 12 - Bos taurus (Bovine)| Length = 312 Score = 73.6 bits (179), Expect = 2e-12 Identities = 49/194 (25%), Positives = 100/194 (51%), Gaps = 3/194 (1%) Frame = +1 Query: 175 GKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMD 354 G+ +TG + GIG+ + + A G K++L +R++++L++V I K + + + +D Sbjct: 50 GEWAVVTGGTDGIGKSYAEELAKRGMKIVLISRSQDKLDQVSSEISEKFK-VETKTIAVD 108 Query: 355 LSSDEKSLKEVVHSAESLFSSAGIDYMMHNA--AFERPKRGA-LEETEEGLKATFKVNVF 525 +S++ + ++ + I +++N ++E P+ + + + +K VN Sbjct: 109 FTSED-----IYDKIKASLAGLNIGVLVNNVGMSYEYPEYFLDVPDLDNTIKKLITVNAL 163 Query: 526 GTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTK 705 +TRL+ P M++R G + +SSA+G P P +YSA+K ++ + L E +K Sbjct: 164 SVCKMTRLVLPGMVERSKGAILNISSASGMYPVPLLTIYSATKAFVDFFSQCLHEEYKSK 223 Query: 706 GIKVTVVCPGPIET 747 G+ V V P + T Sbjct: 224 GVIVQSVLPYYVAT 237
>P15428:PGDH_HUMAN 15-hydroxyprostaglandin dehydrogenase [NAD+] - Homo sapiens (Human)| Length = 266 Score = 73.2 bits (178), Expect = 2e-12 Identities = 54/198 (27%), Positives = 94/198 (47%), Gaps = 5/198 (2%) Frame = +1 Query: 169 VDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLP 348 V+GKV +TGA++GIG + GAK+ L N E + K + + K + Sbjct: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQ 62 Query: 349 MDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFG 528 D+ +D++ L++ F +D +++NA E+ + T ++N+ Sbjct: 63 CDV-ADQQQLRDTFRKVVDHFGR--LDILVNNAGV---------NNEKNWEKTLQINLVS 110 Query: 529 TITLTRLLAPFMLDRGMGH---FVVMSSAAGKVPTPGQALYSASKHALNGY--FASLRSE 693 I+ T L +M + G + MSS AG +P Q +Y ASKH + G+ A+L + Sbjct: 111 VISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAAN 170 Query: 694 LCTKGIKVTVVCPGPIET 747 L G+++ +CPG + T Sbjct: 171 LMNSGVRLNAICPGFVNT 188
>P50163:TRN2_DATST Tropinone reductase 2 - Datura stramonium (Jimsonweed) (Common| thornapple) Length = 260 Score = 72.8 bits (177), Expect = 3e-12 Identities = 63/221 (28%), Positives = 105/221 (47%) Frame = +1 Query: 160 RDKVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVE 339 R ++G +TG SRGIG + + ASLGA + +RN++EL SK KVE Sbjct: 4 RWNLEGCTALVTGGSRGIGYGIVEELASLGASVYTCSRNQKELNDCLTQWRSK--GFKVE 61 Query: 340 VLPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVN 519 DLSS + +E++++ + F ++ +++NA K A + T E +N Sbjct: 62 ASVCDLSSRSER-QELMNTVANHFHGK-LNILVNNAGIVIYKE-AKDYTVEDYSLIMSIN 118 Query: 520 VFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELC 699 L+ L PF+ G+ V +SS +G + P +A+Y A+K A++ L E Sbjct: 119 FEAAYHLSVLAHPFLKASERGNVVFISSVSGALAVPYEAVYGATKGAMDQLTRCLAFEWA 178 Query: 700 TKGIKVTVVCPGPIETPESSGATSSSQRHSSEKRVSVERCA 822 I+V V PG I T ++ + ++ ++RCA Sbjct: 179 KDNIRVNGVGPGVIATSLVEMTIQDPEQKENLNKL-IDRCA 218
>Q1RKB7:FABG_RICBR 3-oxoacyl-[acyl-carrier-protein] reductase - Rickettsia bellii| (strain RML369-C) Length = 241 Score = 72.8 bits (177), Expect = 3e-12 Identities = 53/193 (27%), Positives = 88/193 (45%) Frame = +1 Query: 169 VDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLP 348 + G+ ITGAS GIG ++ Q LG+ +I+S N+E+L+ + +++ + ++V Sbjct: 4 LSGQTALITGASGGIGGAIARQLHKLGSHVIISGSNEEKLKALGNDLKDNYT---IKVCN 60 Query: 349 MDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFG 528 + + + +L + + L +AGI A+ E +N+ Sbjct: 61 LTNTEECSNLVAQIEKLDILVCNAGIT----------KDTLAIRMKNEDFDQVIDINLKA 110 Query: 529 TITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKG 708 L R M+ G + ++S G PGQA Y ASK L G SL E+ T+G Sbjct: 111 NFILNREAIKKMMTNRYGRIINITSIVGVSGNPGQANYCASKAGLIGMTKSLAYEVATRG 170 Query: 709 IKVTVVCPGPIET 747 I V V PG I++ Sbjct: 171 ITVNAVAPGFIKS 183
>P51831:FABG_BACSU 3-oxoacyl-[acyl-carrier-protein] reductase - Bacillus subtilis| Length = 246 Score = 72.8 bits (177), Expect = 3e-12 Identities = 54/194 (27%), Positives = 94/194 (48%), Gaps = 1/194 (0%) Frame = +1 Query: 169 VDGKVVWITGASRGIGEVLSMQFASLGAKLILS-ARNKEELERVKHNIMSKHPDSKVEVL 345 ++ K +TGASRGIG +++ A GA ++++ + N+ + V I S K + Sbjct: 2 LNDKTAIVTGASRGIGRSIALDLAKSGANVVVNYSGNEAKANEVVDEIKSM--GRKAIAV 59 Query: 346 PMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVF 525 D+S+ E ++ ++ S+FS+ ID +++NA R + E+ +N+ Sbjct: 60 KADVSNPE-DVQNMIKETLSVFST--IDILVNNAGITRDNL-IMRMKEDEWDDVININLK 115 Query: 526 GTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTK 705 G T+ + M+ + G + +SS G PGQA Y A+K + G S EL ++ Sbjct: 116 GVFNCTKAVTRQMMKQRSGRIINVSSIVGVSGNPGQANYVAAKAGVIGLTKSSAKELASR 175 Query: 706 GIKVTVVCPGPIET 747 I V + PG I T Sbjct: 176 NITVNAIAPGFIST 189
>Q71R50:DHR11_CHICK Dehydrogenase/reductase SDR family member 11 precursor - Gallus| gallus (Chicken) Length = 255 Score = 72.8 bits (177), Expect = 3e-12 Identities = 66/224 (29%), Positives = 101/224 (45%), Gaps = 21/224 (9%) Frame = +1 Query: 175 GKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMD 354 G+V +TGAS GIG ++ G K++ AR+ +++E++ S + D Sbjct: 6 GRVALVTGASVGIGAAVARALVQHGMKVVGCARSVDKIEKLAAECQSAGYPGTLIPYKCD 65 Query: 355 LSSDEKSLKEVVHSAESLFSS-----AGIDYMMHNAAFERPKRGALEETEEGLKATFKVN 519 LS++E+ L S+FS+ G+D ++NA RP+ L EG + VN Sbjct: 66 LSNEEEIL--------SMFSAIKTLHQGVDVCINNAGLARPE-PLLSGKTEGWRTMIDVN 116 Query: 520 VFGTITLTRLLAPFMLDRGM--GHFVVMSSAAGK--VPTPGQALYSASKHALNGYFASLR 687 V TR M +R + GH + ++S G VP YSA+K+A+ LR Sbjct: 117 VMAVSICTREAYQSMKERNIDDGHIININSMNGHSVVPQSVVHFYSATKYAVTALTEGLR 176 Query: 688 SEL--CTKGIKVTVVCPGPIET----------PESSGATSSSQR 783 EL I+ T + PG +ET PE + AT S R Sbjct: 177 QELREAKTHIRATCISPGLVETGFAFKLHDNDPERAAATYESIR 220
>Q9BPX1:DHR10_HUMAN Dehydrogenase/reductase SDR family member 10 - Homo sapiens (Human)| Length = 270 Score = 72.8 bits (177), Expect = 3e-12 Identities = 49/192 (25%), Positives = 94/192 (48%) Frame = +1 Query: 175 GKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMD 354 GKVV +TG RGIG + F + GA++++ +++ ++ + P + + + Sbjct: 9 GKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQEL----PGAVFILCDVT 64 Query: 355 LSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTI 534 D K+L +E++ +D +++NA P + E + +G + ++N+ GT Sbjct: 65 QEDDVKTLV-----SETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTY 119 Query: 535 TLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 714 TLT+L P+ L + G+ + +SS G + Y A+K A+ +L + G++ Sbjct: 120 TLTKLALPY-LRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVR 178 Query: 715 VTVVCPGPIETP 750 V + PG I TP Sbjct: 179 VNCISPGNIWTP 190
>Q13268:DHRS2_HUMAN Dehydrogenase/reductase SDR family member 2 - Homo sapiens (Human)| Length = 258 Score = 72.4 bits (176), Expect = 4e-12 Identities = 55/202 (27%), Positives = 96/202 (47%) Frame = +1 Query: 142 SCGRPRRDKVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKH 321 S G R+ + +V +TG++ GIG ++ + A GA +++S+R ++ ++R + + Sbjct: 3 STGIDRKGVLANRVAVVTGSTSGIGFAIARRLARDGAHVVISSRKQQNVDRAMAKLQGEG 62 Query: 322 PDSKVEVLPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLK 501 V + + D + L A++L G+D+++ +A L +E+ Sbjct: 63 LSVAGIVCHVGKAEDREQL-----VAKALEHCGGVDFLVCSAGVNPLVGSTLGTSEQIWD 117 Query: 502 ATFKVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFAS 681 VNV L L P+M +R G +++SS A P +Y+ SK AL G + Sbjct: 118 KILSVNVKSPALLLSQLLPYMENR-RGAVILVSSIAAYNPVVALGVYNVSKTALLGLTRT 176 Query: 682 LRSELCTKGIKVTVVCPGPIET 747 L EL K I+V V PG I+T Sbjct: 177 LALELAPKDIRVNCVVPGIIKT 198
>P12310:DHG_BACSU Glucose 1-dehydrogenase - Bacillus subtilis| Length = 261 Score = 72.4 bits (176), Expect = 4e-12 Identities = 68/239 (28%), Positives = 115/239 (48%), Gaps = 9/239 (3%) Frame = +1 Query: 175 GKVVWITGASRGIGEVLSMQFASLGAKLILSA-RNKEELERVKHNIMSKHPDSKVEVLPM 351 GKVV ITGA+ G+G+ ++++F AK++++ NK++ VK ++ + V+ Sbjct: 7 GKVVAITGAASGLGKAMAIRFGKEQAKVVINYYSNKQDPNEVKEEVIKA--GGEAVVVQG 64 Query: 352 DLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKV---NV 522 D++ +E +K +V +A F + +D M++NA E P + E LK KV N+ Sbjct: 65 DVTKEE-DVKNIVQTAIKEFGT--LDIMINNAGLENP----VPSHEMPLKDWDKVIGTNL 117 Query: 523 FGTITLTRLLAPFMLDRGM-GHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELC 699 G +R + ++ + G+ + MSS +P P Y+ASK + +L E Sbjct: 118 TGAFLGSREAIKYFVENDIKGNVINMSSVHEVIPWPLFVHYAASKGGIKLMTETLALEYA 177 Query: 700 TKGIKVTVVCPGPIETP-ESSGATSSSQRHSSEKRVS---VERCAELTIVAATHGLKEA 864 KGI+V + PG I TP + Q+ E + + E+ VAA KEA Sbjct: 178 PKGIRVNNIGPGAINTPINAEKFADPKQKADVESMIPMGYIGEPEEIAAVAAWLASKEA 236
>P50203:PHAB_ACISR Acetoacetyl-CoA reductase - Acinetobacter sp. (strain RA3849)| Length = 248 Score = 72.0 bits (175), Expect = 5e-12 Identities = 66/226 (29%), Positives = 107/226 (47%), Gaps = 4/226 (1%) Frame = +1 Query: 178 KVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSK-HPDSKVEVLPMD 354 KV +TGA GIG + Q + G K+I + +EE +R K + S+ DS V + D Sbjct: 5 KVALVTGALGGIGSEICRQLVTAGYKIIATVVPREE-DREKQWLQSEGFQDSDVRFVLTD 63 Query: 355 LSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERP---KRGALEETEEGLKATFKVNVF 525 L++ E + + E++ + +D +++NA R K+ + E+ + + K Sbjct: 64 LNNHEAATAAI---QEAIAAEGRVDVLVNNAGITRDATFKKMSYEQWSQVIDTNLKT--- 117 Query: 526 GTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTK 705 T+T+ + ML++ G V +SS G GQA YSASK + G+ +L E Sbjct: 118 -LFTVTQPVFNKMLEQKSGRIVNISSVNGLKGQFGQANYSASKAGIIGFTKALAQEGARS 176 Query: 706 GIKVTVVCPGPIETPESSGATSSSQRHSSEKRVSVERCAELTIVAA 843 I V VV PG TP + A S E ++ ++R A +AA Sbjct: 177 NICVNVVAPGYTATPMVT-AMREDVIKSIEAQIPLQRLAAPAEIAA 221
>P70684:PGDH_CAVPO 15-hydroxyprostaglandin dehydrogenase [NAD+] - Cavia porcellus| (Guinea pig) Length = 265 Score = 72.0 bits (175), Expect = 5e-12 Identities = 54/198 (27%), Positives = 96/198 (48%), Gaps = 5/198 (2%) Frame = +1 Query: 169 VDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLP 348 V+GKV +TGA++GIG + GAK+ L N E + K + + K + Sbjct: 3 VNGKVALVTGAAQGIGRAFAEGLLHKGAKVALVDWNLEAGVKCKAALDEEFEPQKTLFIQ 62 Query: 349 MDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFG 528 D+ +D++ L++ F +D +++NA E+ + T ++N+ Sbjct: 63 CDV-ADQEQLRDTFTKVVDYFGR--LDILVNNAGV---------NNEKNWEKTLQINLVS 110 Query: 529 TITLTRLLAPFMLDR--GMGHFVV-MSSAAGKVPTPGQALYSASKHALNGY--FASLRSE 693 I+ T L +M + G G ++ MSS AG +P Q +Y ASKH + G+ A++ + Sbjct: 111 VISGTYLGLDYMSKQHGGEGGVIINMSSLAGLMPVAQQPVYCASKHGIIGFTRSAAMARK 170 Query: 694 LCTKGIKVTVVCPGPIET 747 L G+++ +CPG + T Sbjct: 171 LMNSGVRMNAICPGFVNT 188
>P50198:LINX_PSEPA 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase -| Pseudomonas paucimobilis (Sphingomonas paucimobilis) Length = 250 Score = 72.0 bits (175), Expect = 5e-12 Identities = 53/197 (26%), Positives = 89/197 (45%), Gaps = 1/197 (0%) Frame = +1 Query: 163 DKVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEV 342 +++ GKV ITG + G+G + +FA GAK+++ N+E + V I + D+ Sbjct: 3 NRLAGKVALITGGASGLGAAQAKRFAEEGAKVVIGDLNEEMAKGVVAEIRAAGGDALFIR 62 Query: 343 LPM-DLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVN 519 L + D +S ++ V L + + ++H FE EE+ EG VN Sbjct: 63 LDVTDAASWNNAIAAAVDGFGGLTTLSNTAGIIHPGGFE-------EESIEGWNKMVAVN 115 Query: 520 VFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELC 699 + P ++ G G + +SS G PT G A Y A+K A+ + E Sbjct: 116 QTAIFLGIKAAIPELVKSGNGSIINISSLIGMFPTAGNASYCATKAAVRIMSKAAALEFV 175 Query: 700 TKGIKVTVVCPGPIETP 750 +G++V + PG + TP Sbjct: 176 DRGVRVNTIVPGGMNTP 192
>O54438:FABG_PSEAE 3-oxoacyl-[acyl-carrier-protein] reductase - Pseudomonas aeruginosa| Length = 247 Score = 72.0 bits (175), Expect = 5e-12 Identities = 57/228 (25%), Positives = 104/228 (45%) Frame = +1 Query: 169 VDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLP 348 + GKV +TGASRGIG+ ++++ LGA +I +A + E++ + + + VL Sbjct: 3 LQGKVALVTGASRGIGQAIALELGRLGAVVIGTATSASGAEKIAETLKANGVEGAGLVL- 61 Query: 349 MDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFG 528 D+SSDE + H + L +++NA R + +E N+ Sbjct: 62 -DVSSDESVAATLEHIQQHLGQPL---IVVNNAGITRDNLLVRMKDDEWFDVV-NTNLNS 116 Query: 529 TITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKG 708 L++ + M G + + S G + GQ Y+A+K L G+ +L E+ ++ Sbjct: 117 LYRLSKAVLRGMTKARWGRIINIGSVVGAMGNAGQTNYAAAKAGLEGFTRALAREVGSRA 176 Query: 709 IKVTVVCPGPIETPESSGATSSSQRHSSEKRVSVERCAELTIVAATHG 852 I V V PG I+T + + +QR + ++ + R + +A G Sbjct: 177 ITVNAVAPGFIDT-DMTRELPEAQREALLGQIPLGRLGQAEEIAKVVG 223
>Q9MYP6:DHR10_BOVIN Dehydrogenase/reductase SDR family member 10 - Bos taurus (Bovine)| Length = 270 Score = 72.0 bits (175), Expect = 5e-12 Identities = 49/192 (25%), Positives = 93/192 (48%) Frame = +1 Query: 175 GKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMD 354 GKVV +TG RGIG + F GA++++ +++ V+ + P + + + Sbjct: 9 GKVVIVTGGGRGIGAGIVRAFVESGAQVVICDKDEARGRAVEREL----PGTVFLLCDVT 64 Query: 355 LSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTI 534 D ++L +E++ +D +++NA + P + E + +G + ++N+ GT Sbjct: 65 REEDVRTL-----VSETIRRFGRLDCIVNNAGYHPPPQWPEETSAQGFRQLLELNLLGTY 119 Query: 535 TLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 714 TLT+L P L + G+ + +SS G + Y A+K A+ +L + G++ Sbjct: 120 TLTKLALPH-LRKSRGNVINISSLVGAIGQSQAVPYVATKGAVTAMTKALALDESQYGVR 178 Query: 715 VTVVCPGPIETP 750 V + PG I TP Sbjct: 179 VNCISPGNIWTP 190
>P45375:PHBB_CHRVI Acetoacetyl-CoA reductase - Chromatium vinosum (Allochromatium| vinosum) Length = 246 Score = 71.6 bits (174), Expect = 7e-12 Identities = 58/222 (26%), Positives = 100/222 (45%) Frame = +1 Query: 178 KVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDL 357 ++ +TG GIG + + A G ++ + E + + V D+ Sbjct: 3 RIALVTGGIGGIGTSICTRLAKDGCTVVANCHPSEAAAAEEWKQARAAEGFDIAVFTADV 62 Query: 358 SSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTIT 537 SS + S + V E + ID +++ A R K E + +A VN+ Sbjct: 63 SSFDDSARMVREITEQV---GPIDILVNCAGITRDKTFKKME-QAHWEAVINVNLNSVFN 118 Query: 538 LTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIKV 717 +TR + ML+RG G + +SS G+ GQA YSA+K ++G+ +L E +KG+ V Sbjct: 119 VTRQVWDGMLERGFGRIINISSVNGQRGQFGQANYSAAKAGMHGFTMALAQEGASKGVTV 178 Query: 718 TVVCPGPIETPESSGATSSSQRHSSEKRVSVERCAELTIVAA 843 + PG +ET + A + R+S + + R A+ +AA Sbjct: 179 NTISPGYVETAMTL-AMNDDVRNSIISGIPMRRMAQPNEIAA 219
>Q9LBG2:LVR_LEIAQ Levodione reductase - Leifsonia aquatica (Corynebacterium| aquaticum) Length = 267 Score = 71.6 bits (174), Expect = 7e-12 Identities = 54/191 (28%), Positives = 85/191 (44%) Frame = +1 Query: 178 KVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDL 357 +VV ITG G+G +++ A+ GAKL L + E LE K ++ PD++V D+ Sbjct: 14 RVVLITGGGSGLGRATAVRLAAEGAKLSLVDVSSEGLEASKAAVLETAPDAEVLTTVADV 73 Query: 358 SSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTIT 537 S DE ++ V + F ID +NA E + T +N+ G Sbjct: 74 S-DEAQVEAYVTATTERFGR--IDGFFNNAGIEGKQNPTESFTAAEFDKVVSINLRGVFL 130 Query: 538 LTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIKV 717 + M ++G G V +S G Q+ Y+A+KH + G + E GI++ Sbjct: 131 GLEKVLKIMREQGSGMVVNTASVGGIRGIGNQSGYAAAKHGVVGLTRNSAVEYGRYGIRI 190 Query: 718 TVVCPGPIETP 750 + PG I TP Sbjct: 191 NAIAPGAIWTP 201
>Q3ZBV9:DHR11_BOVIN Dehydrogenase/reductase SDR family member 11 precursor - Bos taurus| (Bovine) Length = 255 Score = 71.6 bits (174), Expect = 7e-12 Identities = 64/218 (29%), Positives = 97/218 (44%), Gaps = 21/218 (9%) Frame = +1 Query: 178 KVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDL 357 ++ +TGAS GIG ++ G K++ AR +E + S + DL Sbjct: 7 RLALVTGASGGIGAAVARALVQQGLKVVGCARTVGNIEELAAECKSAGYPGTLIPYRCDL 66 Query: 358 SSDEKSLKEVVHSAESLFSS-----AGIDYMMHNAAFERPKRGALEETEEGLKATFKVNV 522 S++E L S+FS+ +G+D ++NA RP L + G K F VNV Sbjct: 67 SNEEDIL--------SMFSAVRSQHSGVDICINNAGLARPDT-LLSGSTSGWKEMFNVNV 117 Query: 523 FGTITLTRLLAPFMLDRGM--GHFVVMSSAAG-KVPTPGQA-LYSASKHALNGYFASLRS 690 TR M +R + GH + ++S G +VP P + YSA+K+A+ LR Sbjct: 118 LALSICTREACQSMRERKVDDGHIININSMCGHRVPPPAETHFYSATKYAVTALTEGLRQ 177 Query: 691 EL--CTKGIKVTVVCPGPIET----------PESSGAT 768 EL I+ T + PG +ET PE + AT Sbjct: 178 ELREARSHIRATCISPGVVETQFAFKLHDKDPEKAAAT 215
>P25970:Y5909_MYXXD Uncharacterized oxidoreductase MXAN_5909 - Myxococcus xanthus| (strain DK 1622) Length = 253 Score = 71.2 bits (173), Expect = 9e-12 Identities = 53/187 (28%), Positives = 93/187 (49%), Gaps = 1/187 (0%) Frame = +1 Query: 190 ITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDE 369 +TGAS G+G L++ A G ++ + R +L+ ++ + VE + +D++ + Sbjct: 11 VTGASSGLGRGLALWLARRGVRVFAAGRRLPQLQALRDEAQAA--GVTVEPVELDVTKAD 68 Query: 370 KSLKEVVHSAESLFSSAG-IDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTR 546 +L+ + +L + AG +D ++ NA A E ++ NV G Sbjct: 69 ATLERI----RALDAEAGGLDLVVANAGVGGTTN-AKRLPWERVRGIIDTNVTGAAATLS 123 Query: 547 LLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIKVTVV 726 + P M++R GH V +SS AG G A YSASK L+ + SLR +L G++VT + Sbjct: 124 AVLPQMVERKRGHLVGVSSLAGFRGLAGHAAYSASKAFLSTFMESLRVDLRGTGVRVTCI 183 Query: 727 CPGPIET 747 PG +++ Sbjct: 184 YPGFVKS 190
>Q5KTS5:GRDH_DAUCA Glucose and ribitol dehydrogenase - Daucus carota (Carrot)| Length = 291 Score = 71.2 bits (173), Expect = 9e-12 Identities = 60/203 (29%), Positives = 103/203 (50%), Gaps = 7/203 (3%) Frame = +1 Query: 163 DKVDGKVVWITGASRGIGEVLSMQFASLGAKL----ILSARNKEELERVKHNIMSKHPDS 330 +K+ GKV +TG GIG + FA GA + + +K+ E ++ +K D+ Sbjct: 37 NKLQGKVALVTGGDSGIGRSVCYHFALEGATVAFTFVKGHEDKDANETLELLRKAKSSDA 96 Query: 331 KVEV-LPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEET-EEGLKA 504 K + + DL D+ + K+VV + F S ID +++NAA E+ K +E+ EE L+ Sbjct: 97 KDPIAIAADLGFDD-NCKKVVDQVVNAFGS--IDVLVNNAA-EQYKASTVEDIDEERLER 152 Query: 505 TFKVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQAL-YSASKHALNGYFAS 681 F+ N+F + R M + G ++ +++ + L Y+A+K A+ + Sbjct: 153 VFRTNIFAYFFMARHALKHMRE---GSTIINTTSINAYKGNAKLLDYTATKGAIVAFTRG 209 Query: 682 LRSELCTKGIKVTVVCPGPIETP 750 L +L +KGI+V V PGP+ TP Sbjct: 210 LSLQLISKGIRVNGVAPGPVWTP 232
>Q53GQ0:DHB12_HUMAN Estradiol 17-beta-dehydrogenase 12 - Homo sapiens (Human)| Length = 312 Score = 71.2 bits (173), Expect = 9e-12 Identities = 49/191 (25%), Positives = 101/191 (52%), Gaps = 5/191 (2%) Frame = +1 Query: 175 GKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEV--LP 348 G+ +TG++ GIG+ + + A G K++L +R+K++L++V I K KVE + Sbjct: 50 GEWAVVTGSTDGIGKSYAEELAKHGMKVVLISRSKDKLDQVSSEIKEKF---KVETRTIA 106 Query: 349 MDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNA--AFERPKRGA-LEETEEGLKATFKVN 519 +D +S++ + ++ + I +++N ++E P+ + + + +K +N Sbjct: 107 VDFASED-----IYDKIKTGLAGLEIGILVNNVGMSYEYPEYFLDVPDLDNVIKKMININ 161 Query: 520 VFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELC 699 + +T+L+ P M++R G + +SS +G +P P +YSA+K ++ + L E Sbjct: 162 ILSVCKMTQLVLPGMVERSKGAILNISSGSGMLPVPLLTIYSATKTFVDFFSQCLHEEYR 221 Query: 700 TKGIKVTVVCP 732 +KG+ V V P Sbjct: 222 SKGVFVQSVLP 232
>O05730:VDLC_HELPY Probable short-chain type dehydrogenase/reductase vdlC -| Helicobacter pylori (Campylobacter pylori) Length = 284 Score = 70.9 bits (172), Expect = 1e-11 Identities = 61/217 (28%), Positives = 101/217 (46%), Gaps = 1/217 (0%) Frame = +1 Query: 166 KVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVL 345 K KV ITGAS GIG ++ G K+ +R+ + H + E + Sbjct: 7 KESQKVAIITGASSGIGLECALMLLDQGYKVYALSRHATLCVALNHALC--------ESV 58 Query: 346 PMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETE-EGLKATFKVNV 522 +D+S D +LKEV + + D ++++A + G++E+T E +K F VN Sbjct: 59 DIDVS-DSNALKEVFSNISA--KEKYCDVLINSAGYG--VFGSVEDTPIEEVKKQFSVNF 113 Query: 523 FGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCT 702 F + + P + ++ +SS AG+V YSASKHAL Y +LR EL Sbjct: 114 FALCEVVQFCLPLLKNKPHSKIFNLSSIAGRVSMLFLGHYSASKHALEAYSDALRLELKP 173 Query: 703 KGIKVTVVCPGPIETPESSGATSSSQRHSSEKRVSVE 813 ++V ++ PGP+++ A S S + ++E Sbjct: 174 FNVQVCLIEPGPVKSNWEKTAFSVENFESEDSLYALE 210
>Q56840:HCDR_XANP2 2-(R)-hydroxypropyl-CoM dehydrogenase - Xanthobacter sp. (strain| Py2) Length = 250 Score = 70.9 bits (172), Expect = 1e-11 Identities = 62/196 (31%), Positives = 92/196 (46%), Gaps = 5/196 (2%) Frame = +1 Query: 178 KVVWITGASRGIGEVLSMQFASLG---AKLILSARNKEELERVKHNIMSKHPDSKVEVLP 348 +V +TGAS G G ++ +F + G A L LSA EE R + + KV + Sbjct: 3 RVAIVTGASSGNGLAIATRFLARGDRVAALDLSAETLEETARTHWHAYA----DKVLRVR 58 Query: 349 MDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFE-RPKRGALEETE-EGLKATFKVNV 522 D++ DE + + + F + ID +++NA + G L T E VNV Sbjct: 59 ADVA-DEGDVNAAIAATMEQFGA--IDVLVNNAGITGNSEAGVLHTTPVEQFDKVMAVNV 115 Query: 523 FGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCT 702 G R + P ML +G G V ++S A V PG++ Y+ SK A+ S+ + Sbjct: 116 RGIFLGCRAVLPHMLLQGAGVIVNIASVASLVAFPGRSAYTTSKGAVLQLTKSVAVDYAG 175 Query: 703 KGIKVTVVCPGPIETP 750 GI+ VCPG IETP Sbjct: 176 SGIRCNAVCPGMIETP 191
>Q62730:DHB2_RAT Estradiol 17-beta-dehydrogenase 2 - Rattus norvegicus (Rat)| Length = 381 Score = 70.9 bits (172), Expect = 1e-11 Identities = 55/194 (28%), Positives = 91/194 (46%), Gaps = 1/194 (0%) Frame = +1 Query: 169 VDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLP 348 VD K V +TGA G G L+ LG + +KE + + K+ ++ VL Sbjct: 81 VDQKAVLVTGADSGFGHALAKHLDKLGFTVFAGVLDKEGPGAEE---LRKNCSERLSVLQ 137 Query: 349 MDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNA-AFERPKRGALEETEEGLKATFKVNVF 525 MD++ E+ +K+V G+ +++NA P G L K VN F Sbjct: 138 MDVTKPEQ-IKDVHSEVAEKIQDKGLWAVVNNAGVLHFPIDGELIPMTVYRKC-MAVNFF 195 Query: 526 GTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTK 705 G + +T++ P +L + G V +SS +P A Y+++K A++ + A +R EL Sbjct: 196 GAVEVTKVFLP-LLRKSKGRLVNVSSMGAMIPFQMVAAYASTKAAISMFSAVIRQELAKW 254 Query: 706 GIKVTVVCPGPIET 747 G+KV + PG +T Sbjct: 255 GVKVVTIHPGGFQT 268
>Q17704:DHBW_CAEEL Putative steroid dehydrogenase C06B3.5 - Caenorhabditis elegans| Length = 349 Score = 70.5 bits (171), Expect = 2e-11 Identities = 60/205 (29%), Positives = 94/205 (45%), Gaps = 9/205 (4%) Frame = +1 Query: 190 ITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLS--- 360 ITG + GIG+ S + A G + + +R + +LE+ K IM K+ + +V D + Sbjct: 52 ITGGTDGIGKSFSFELAKRGFNIYIVSRTQSKLEQTKKEIMEKYSNVEVRFATFDFTNPS 111 Query: 361 -SDEKSLKEVVHSAESLFSSAGIDYMMHNAA--FERPKRGALEETEEGLKATFKVNVFGT 531 SD K L S + I +++N FE P+ L +T G+ V + T Sbjct: 112 ISDYKKLL-------SQLNEVSIGMLINNVGMLFEYPEN--LHKTVGGIDVVANVTILNT 162 Query: 532 ITLTRLLA---PFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCT 702 + +T L A P M+ R G V + S AG ++YSASK + LR E Sbjct: 163 LPVTLLSAGILPQMVSRKTGIIVNIGSVAGAAKMAEWSVYSASKKYVEWLTGCLRKEYEH 222 Query: 703 KGIKVTVVCPGPIETPESSGATSSS 777 +GI + + P + T + SG T +S Sbjct: 223 QGIIIQAITPALVAT-KLSGHTETS 246
>P0AET8:HDHA_ECOLI 7-alpha-hydroxysteroid dehydrogenase - Escherichia coli| Length = 255 Score = 70.1 bits (170), Expect = 2e-11 Identities = 53/195 (27%), Positives = 96/195 (49%), Gaps = 1/195 (0%) Frame = +1 Query: 166 KVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVL 345 ++DGK ITGA GIG+ +++ FA+ GA +++S N + V I + Sbjct: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQL--GGQAFAC 65 Query: 346 PMDLSSDEKSLKEVVHSAESLFSSAG-IDYMMHNAAFERPKRGALEETEEGLKATFKVNV 522 D++S++ E+ A+ S G +D +++NA PK + + + +++NV Sbjct: 66 RCDITSEQ----ELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMAD--FRRAYELNV 119 Query: 523 FGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCT 702 F L++L+AP M G G + ++S A + Y++SK A + ++ +L Sbjct: 120 FSFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGE 179 Query: 703 KGIKVTVVCPGPIET 747 K I+V + PG I T Sbjct: 180 KNIRVNGIAPGAILT 194
>P0AET9:HDHA_ECO57 7-alpha-hydroxysteroid dehydrogenase - Escherichia coli O157:H7| Length = 255 Score = 70.1 bits (170), Expect = 2e-11 Identities = 53/195 (27%), Positives = 96/195 (49%), Gaps = 1/195 (0%) Frame = +1 Query: 166 KVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVL 345 ++DGK ITGA GIG+ +++ FA+ GA +++S N + V I + Sbjct: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQL--GGQAFAC 65 Query: 346 PMDLSSDEKSLKEVVHSAESLFSSAG-IDYMMHNAAFERPKRGALEETEEGLKATFKVNV 522 D++S++ E+ A+ S G +D +++NA PK + + + +++NV Sbjct: 66 RCDITSEQ----ELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMAD--FRRAYELNV 119 Query: 523 FGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCT 702 F L++L+AP M G G + ++S A + Y++SK A + ++ +L Sbjct: 120 FSFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGE 179 Query: 703 KGIKVTVVCPGPIET 747 K I+V + PG I T Sbjct: 180 KNIRVNGIAPGAILT 194
>Q4UK62:FABG_RICFE 3-oxoacyl-[acyl-carrier-protein] reductase - Rickettsia felis| (Rickettsia azadi) Length = 241 Score = 70.1 bits (170), Expect = 2e-11 Identities = 56/210 (26%), Positives = 97/210 (46%) Frame = +1 Query: 175 GKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMD 354 GK ITGAS GIG ++ LG+ +I+S N+E+L+ + + + + +E+ + Sbjct: 6 GKTSLITGASGGIGGAIARLLHKLGSHVIISGSNEEKLKSLGNVLKDNYT---IEICNL- 61 Query: 355 LSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTI 534 ++++ ++ A L D ++ NA A+ +E +N+ Sbjct: 62 --ANKEECSNLISKAPKL------DILVCNAGITSDTL-AIRMKDEDFDKVIDINLKANF 112 Query: 535 TLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 714 L R M+ G + +SS G PGQA Y ASK L G SL E+ T+GI Sbjct: 113 ILNREAIKKMMQNRYGRIINISSIVGISGNPGQANYCASKAGLIGMTKSLSYEVATRGIT 172 Query: 715 VTVVCPGPIETPESSGATSSSQRHSSEKRV 804 V V PG I++ + + + QR + +++ Sbjct: 173 VNAVAPGFIKS-DMTDKLNEKQREAIVQKI 201
>Q93X68:FABG5_BRANA 3-oxoacyl-[acyl-carrier-protein] reductase 5, chloroplast precursor| - Brassica napus (Rape) Length = 317 Score = 70.1 bits (170), Expect = 2e-11 Identities = 51/191 (26%), Positives = 93/191 (48%), Gaps = 1/191 (0%) Frame = +1 Query: 166 KVDGKVVWITGASRGIGEVLSMQFASLGAKLILS-ARNKEELERVKHNIMSKHPDSKVEV 342 KV+ VV +TGASRGIG+ +++ G K++++ AR+ +E E V I + + Sbjct: 71 KVESPVVVVTGASRGIGKAIALSLGKAGCKVLVNYARSAKEAEEVSKQI--EEYGGEAIT 128 Query: 343 LPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNV 522 D+S E + ++ +A + + ID +++NA R + + +N+ Sbjct: 129 FGGDVSK-EADVDSMMKTAVDKWGT--IDVVVNNAGITRDTL-LIRMKKSQWDEVIDLNL 184 Query: 523 FGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCT 702 G T+ M+ + G + ++S G + GQA Y+A+K + G+ + E + Sbjct: 185 TGVFLCTQAATKIMMKKRKGRIINIASVVGLIGNIGQANYAAAKAGVIGFSKTAAREGAS 244 Query: 703 KGIKVTVVCPG 735 + I V VVCPG Sbjct: 245 RNINVNVVCPG 255
>Q949M3:FABG3_BRANA 3-oxoacyl-[acyl-carrier-protein] reductase 3, chloroplast precursor| - Brassica napus (Rape) Length = 315 Score = 70.1 bits (170), Expect = 2e-11 Identities = 51/191 (26%), Positives = 94/191 (49%), Gaps = 1/191 (0%) Frame = +1 Query: 166 KVDGKVVWITGASRGIGEVLSMQFASLGAKLILS-ARNKEELERVKHNIMSKHPDSKVEV 342 KV+ VV +TGASRGIG+ +++ G K++++ AR+ +E E V I + + Sbjct: 69 KVESPVVVVTGASRGIGKAIALSLGKAGCKVLVNYARSAKEAEEVSKQIEAY--GGQAIT 126 Query: 343 LPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNV 522 D+S E ++ ++ +A + + ID +++NA R + + +N+ Sbjct: 127 FGGDVSK-EADVEAMMKTAIDAWGT--IDVVVNNAGITRDTL-LIRMKKSQWDEVIDLNL 182 Query: 523 FGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCT 702 G T+ M+ + G + ++S G + GQA Y+A+K + G+ + E + Sbjct: 183 TGVFLCTQAATKIMMKKRKGRIINIASVVGLIGNIGQANYAAAKAGVIGFSKTAAREGAS 242 Query: 703 KGIKVTVVCPG 735 + I V VVCPG Sbjct: 243 RNINVNVVCPG 253
>Q93X67:FABG2_BRANA 3-oxoacyl-[acyl-carrier-protein] reductase 2, chloroplast precursor| - Brassica napus (Rape) Length = 328 Score = 70.1 bits (170), Expect = 2e-11 Identities = 51/191 (26%), Positives = 94/191 (49%), Gaps = 1/191 (0%) Frame = +1 Query: 166 KVDGKVVWITGASRGIGEVLSMQFASLGAKLILS-ARNKEELERVKHNIMSKHPDSKVEV 342 KV+ VV +TGASRGIG+ +++ G K++++ AR+ +E E+V I + + Sbjct: 82 KVESPVVVVTGASRGIGKAIALSLGKAGCKVLVNYARSAKEAEQVSKQIEAY--GGQAIT 139 Query: 343 LPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNV 522 D+S E + ++ +A + + ID +++NA R + + +N+ Sbjct: 140 FGGDVSK-EADVDAMMKTAVDAWGT--IDVVVNNAGITRDTL-LIRMKKSQWDEVIDLNL 195 Query: 523 FGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCT 702 G T+ M+ + G + ++S G + GQA Y+A+K + G+ + E + Sbjct: 196 TGVFLCTQAATKIMMKKRKGRIINIASVVGLIGNIGQANYAAAKAGVIGFSKTAAREGAS 255 Query: 703 KGIKVTVVCPG 735 + I V VVCPG Sbjct: 256 RNINVNVVCPG 266
>Q93X62:FABG1_BRANA 3-oxoacyl-[acyl-carrier-protein] reductase 1, chloroplast precursor| - Brassica napus (Rape) Length = 320 Score = 70.1 bits (170), Expect = 2e-11 Identities = 51/191 (26%), Positives = 94/191 (49%), Gaps = 1/191 (0%) Frame = +1 Query: 166 KVDGKVVWITGASRGIGEVLSMQFASLGAKLILS-ARNKEELERVKHNIMSKHPDSKVEV 342 KV+ VV +TGASRGIG+ +++ G K++++ AR+ +E E V I + + Sbjct: 74 KVESPVVVVTGASRGIGKAIALSLGKAGCKVLVNYARSAKEAEEVSKQIEAY--GGQAIT 131 Query: 343 LPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNV 522 D+S E ++ ++ +A + + ID +++NA R + + +N+ Sbjct: 132 FGGDVSK-EADVEAMMKTAIDAWGT--IDVVVNNAGITRDTL-LIRMKKSQWDEVIDLNL 187 Query: 523 FGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCT 702 G T+ M+ + G + ++S G + GQA Y+A+K + G+ + E + Sbjct: 188 TGVFLCTQAATKIMMKKRKGRIINIASVVGLIGNIGQANYAAAKAGVIGFSKTAAREGAS 247 Query: 703 KGIKVTVVCPG 735 + I V VVCPG Sbjct: 248 RNINVNVVCPG 258
>P66777:EPHD_MYCTU Probable oxidoreductase ephD - Mycobacterium tuberculosis| Length = 592 Score = 70.1 bits (170), Expect = 2e-11 Identities = 59/202 (29%), Positives = 96/202 (47%), Gaps = 2/202 (0%) Frame = +1 Query: 148 GRPRRDKVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPD 327 GRPR D +V +TGA GIG ++ FA GA++++S ++ ++ I ++ Sbjct: 316 GRPRGYFGD-TLVSVTGAGSGIGRETALAFAREGAEIVISDIDEATVKDTAAEIAARGGI 374 Query: 328 SKVEVLPMDLSSDEKSLKEVVHSAESLFSSAGI-DYMMHNAAFERPKRGALEETEEGLKA 504 + VL D + V AE + + G+ D +++NA + R L+ E Sbjct: 375 AYPYVL------DVSDAEAVEAFAERVSAEHGVPDIVVNNAGIGQAGR-FLDTPAEQFDR 427 Query: 505 TFKVNVFGTITLTRLLAPFMLDRGM-GHFVVMSSAAGKVPTPGQALYSASKHALNGYFAS 681 VN+ G + R +++RG GH V +SS A P + Y SK A + Sbjct: 428 VLAVNLGGVVNGCRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKAATYMFSDC 487 Query: 682 LRSELCTKGIKVTVVCPGPIET 747 LR+EL G+ +T +CPG I+T Sbjct: 488 LRAELDAAGVGLTTICPGVIDT 509
>P66778:EPHD_MYCBO Probable oxidoreductase ephD - Mycobacterium bovis| Length = 592 Score = 70.1 bits (170), Expect = 2e-11 Identities = 59/202 (29%), Positives = 96/202 (47%), Gaps = 2/202 (0%) Frame = +1 Query: 148 GRPRRDKVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPD 327 GRPR D +V +TGA GIG ++ FA GA++++S ++ ++ I ++ Sbjct: 316 GRPRGYFGD-TLVSVTGAGSGIGRETALAFAREGAEIVISDIDEATVKDTAAEIAARGGI 374 Query: 328 SKVEVLPMDLSSDEKSLKEVVHSAESLFSSAGI-DYMMHNAAFERPKRGALEETEEGLKA 504 + VL D + V AE + + G+ D +++NA + R L+ E Sbjct: 375 AYPYVL------DVSDAEAVEAFAERVSAEHGVPDIVVNNAGIGQAGR-FLDTPAEQFDR 427 Query: 505 TFKVNVFGTITLTRLLAPFMLDRGM-GHFVVMSSAAGKVPTPGQALYSASKHALNGYFAS 681 VN+ G + R +++RG GH V +SS A P + Y SK A + Sbjct: 428 VLAVNLGGVVNGCRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKAATYMFSDC 487 Query: 682 LRSELCTKGIKVTVVCPGPIET 747 LR+EL G+ +T +CPG I+T Sbjct: 488 LRAELDAAGVGLTTICPGVIDT 509
>Q4R5G7:DHB12_MACFA Estradiol 17-beta-dehydrogenase 12 - Macaca fascicularis (Crab| eating macaque) (Cynomolgus monkey) Length = 312 Score = 70.1 bits (170), Expect = 2e-11 Identities = 48/189 (25%), Positives = 99/189 (52%), Gaps = 3/189 (1%) Frame = +1 Query: 175 GKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMD 354 G+ +TG + GIG+ + + A G K++L +R++++L++V I K KVE + Sbjct: 50 GEWAVVTGGTDGIGKSYAEELAKRGMKVVLISRSQDKLDQVSSEIKEKF---KVETRTIA 106 Query: 355 LSSDEKSLKEVVHSAESLFSSAGIDYMMHNA--AFERPKRGA-LEETEEGLKATFKVNVF 525 + + +L+++ ++ + I +++N ++E P+ + + + +K +N+ Sbjct: 107 V---DFTLEDIYDKIKTGLAGLEIGILVNNVGMSYEYPEYFLDVPDLDNVIKKMININIL 163 Query: 526 GTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTK 705 +T+L+ P M++R G + +SS +G P P +YSA+K ++ + L E +K Sbjct: 164 SVCKMTQLVLPGMVERSKGAILNISSGSGMFPVPLLTIYSATKTFVDFFSQCLHEEYRSK 223 Query: 706 GIKVTVVCP 732 GI V V P Sbjct: 224 GIFVQSVLP 232
>Q21929:DCXR_CAEEL Probable L-xylulose reductase - Caenorhabditis elegans| Length = 251 Score = 70.1 bits (170), Expect = 2e-11 Identities = 64/226 (28%), Positives = 113/226 (50%), Gaps = 9/226 (3%) Frame = +1 Query: 178 KVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPM-- 351 K + +TGAS+GIG+ + + A GA++I ARN+ L +++ + + ++P+ Sbjct: 10 KRILVTGASQGIGKEICLSLAKAGAQVIAFARNEANL----LSLVKETTSLRYTIIPIVG 65 Query: 352 DLSSDEKSLKEVV---HSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNV 522 D+S++E+ L +++ L ++AGI + T++ + TF VNV Sbjct: 66 DVSANEEVLFKLIVPHFPIHGLVNNAGI----------ATNHAIGQITQQSIDRTFAVNV 115 Query: 523 FGTITLTRLLAPFMLDRGM-GHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELC 699 G I + +L+A +DR + G V +SS A P +Y ASK AL+ L +EL Sbjct: 116 RGPILIAQLVARNFVDRQIKGSIVNISSQAAIRPLDNHTVYCASKAALDMVTRCLANELG 175 Query: 700 TKGIKVTVVCPGPIETPESSGATSSSQRHSSEK---RVSVERCAEL 828 ++ I+V V P + T G + S +K R+ ++R AE+ Sbjct: 176 SQNIRVNSVNPTVVMT--DMGRDNWSDPDKKKKMLDRMPIKRFAEV 219
>P14802:YOXD_BACSU Uncharacterized oxidoreductase yoxD - Bacillus subtilis| Length = 238 Score = 69.7 bits (169), Expect = 3e-11 Identities = 53/193 (27%), Positives = 88/193 (45%) Frame = +1 Query: 178 KVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDL 357 K ITG RGIG ++ A G + L R +E+V + K K D+ Sbjct: 7 KTALITGGGRGIGRATALALAKEGVNIGLIGRTSANVEKVAEEV--KALGVKAAFAAADV 64 Query: 358 SSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTIT 537 ++ + V E L ID +++NA + G L+ + + + +VN+ G Sbjct: 65 KDADQVNQAVAQVKEQL---GDIDILINNAGISK-FGGFLDLSADEWENIIQVNLMGVYH 120 Query: 538 LTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIKV 717 +TR + P M++R G + +SS AG+ + YSASK A+ G SL E+ I+V Sbjct: 121 VTRAVLPEMIERKAGDIINISSTAGQRGAAVTSAYSASKFAVLGLTESLMQEVRKHNIRV 180 Query: 718 TVVCPGPIETPES 756 + + P + + S Sbjct: 181 SALTPSTVASDMS 193
>Q9ZKW1:VDLC_HELPJ Probable short-chain type dehydrogenase/reductase vdlC -| Helicobacter pylori J99 (Campylobacter pylori J99) Length = 271 Score = 69.7 bits (169), Expect = 3e-11 Identities = 58/202 (28%), Positives = 97/202 (48%), Gaps = 1/202 (0%) Frame = +1 Query: 190 ITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDE 369 ITGAS GIG + + G K+ +R+ + H + E + +D+S D Sbjct: 4 ITGASSGIGLECVLMLLNQGYKVYALSRHATLCVALNHALC--------ECVDIDVS-DS 54 Query: 370 KSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETE-EGLKATFKVNVFGTITLTR 546 +LKEV + + D ++++A + G++E+T E +K F VN F + + Sbjct: 55 NALKEVFLNISA--KEDHCDVLINSAGYG--VFGSVEDTPIEEVKKQFSVNFFALCEVVQ 110 Query: 547 LLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIKVTVV 726 L P + ++ +SS AG+V YSASKHAL Y +LR EL ++V ++ Sbjct: 111 LCLPLLKNKPYSKIFNLSSIAGRVSMLFLGHYSASKHALEAYSDALRLELKPFNVQVCLI 170 Query: 727 CPGPIETPESSGATSSSQRHSS 792 PGP+++ A + +R S Sbjct: 171 EPGPVKSNWEKTAFENDERKDS 192
>P23238:PHBB_ZOORA Acetoacetyl-CoA reductase - Zoogloea ramigera| Length = 241 Score = 69.7 bits (169), Expect = 3e-11 Identities = 57/191 (29%), Positives = 87/191 (45%), Gaps = 1/191 (0%) Frame = +1 Query: 178 KVVWITGASRGIGEVLSMQFASLGAKLILS-ARNKEELERVKHNIMSKHPDSKVEVLPMD 354 +V +TG SRGIG +S+ + G K+ S A N + + K ++ + V D Sbjct: 3 RVALVTGGSRGIGAAISIALKAAGYKVAASYAGNDDAAKPFK-------AETGIAVYKWD 55 Query: 355 LSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTI 534 +SS E ++ + L ID +++NA + + T + A N+ G Sbjct: 56 VSSYEACVEGIAKVEADL---GPIDVLVNNAGITKDAMFH-KMTPDQWNAVINTNLTGLF 111 Query: 535 TLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 714 +T + M DR G V +SS G+ GQA YSA+K G+ +L E KGI Sbjct: 112 NMTHPVWSGMRDRSFGRIVNISSINGQKGQMGQANYSAAKAGDLGFTKALAQEGAAKGIT 171 Query: 715 VTVVCPGPIET 747 V +CPG I T Sbjct: 172 VNAICPGYIGT 182
>Q6UWP2:DHR11_HUMAN Dehydrogenase/reductase SDR family member 11 precursor - Homo| sapiens (Human) Length = 260 Score = 69.7 bits (169), Expect = 3e-11 Identities = 64/227 (28%), Positives = 99/227 (43%), Gaps = 21/227 (9%) Frame = +1 Query: 151 RPRRDKVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDS 330 RP ++ ++ +TGAS GIG ++ G K++ AR +E + S Sbjct: 3 RPGMERWRDRLALVTGASGGIGAAVARALVQQGLKVVGCARTVGNIEELAAECKSAGYPG 62 Query: 331 KVEVLPMDLSSDEKSLKEVVHSAESLFSS-----AGIDYMMHNAAFERPKRGALEETEEG 495 + DLS++E L S+FS+ +G+D ++NA RP L + G Sbjct: 63 TLIPYRCDLSNEEDIL--------SMFSAIRSQHSGVDICINNAGLARPDT-LLSGSTSG 113 Query: 496 LKATFKVNVFGTITLTRLLAPFMLDRGM--GHFVVMSSAAGK--VPTPGQALYSASKHAL 663 K F VNV TR M +R + GH + ++S +G +P YSA+K+A+ Sbjct: 114 WKDMFNVNVLALSICTREAYQSMKERNVDDGHIININSMSGHRVLPLSVTHFYSATKYAV 173 Query: 664 NGYFASLRSEL--CTKGIKVTVVCPGPIET----------PESSGAT 768 LR EL I+ T + PG +ET PE + AT Sbjct: 174 TALTEGLRQELREAQTHIRATCISPGVVETQFAFKLHDKDPEKAAAT 220
>P39483:DHG2_BACME Glucose 1-dehydrogenase 2 - Bacillus megaterium| Length = 261 Score = 69.7 bits (169), Expect = 3e-11 Identities = 55/194 (28%), Positives = 97/194 (50%), Gaps = 3/194 (1%) Frame = +1 Query: 178 KVVWITGASRGIGEVLSMQFASLGAKLILSAR-NKEELERVKHNIMSKHPDSKVEVLPMD 354 KVV +TG S+G+G ++++F +K++++ R N+EE VK I + + ++ D Sbjct: 8 KVVVVTGGSKGLGRAMAVRFGQEQSKVVVNYRSNEEEALEVKKEI--EEAGGQAIIVRGD 65 Query: 355 LSSDEKSLKEVVHSAESLFSSAG-IDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGT 531 ++ +E +VV+ E+ G +D M++NA E P E + E N+ G Sbjct: 66 VTKEE----DVVNLVETAVKEFGSLDVMINNAGVENPVPSH-ELSLENWNQVIDTNLTGA 120 Query: 532 ITLTRLLAPFMLDRGM-GHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKG 708 +R + ++ + G+ + MSS +P P Y+ASK + +L E KG Sbjct: 121 FLGSREAIKYFVENDIKGNVINMSSVHEMIPWPLFVHYAASKGGMKLMTETLALEYAPKG 180 Query: 709 IKVTVVCPGPIETP 750 I+V + PG I+TP Sbjct: 181 IRVNNIGPGAIDTP 194
>P50842:KDUD_BACSU 2-deoxy-D-gluconate 3-dehydrogenase - Bacillus subtilis| Length = 254 Score = 69.3 bits (168), Expect = 4e-11 Identities = 60/228 (26%), Positives = 98/228 (42%), Gaps = 4/228 (1%) Frame = +1 Query: 175 GKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMD 354 GK +TG GIG+ ++ A GA +I ++ E + + + +D Sbjct: 12 GKTALVTGPGTGIGQGIAKALAGAGADIIGTSHTSSLSETQQ---LVEQEGRIFTSFTLD 68 Query: 355 LSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTI 534 +S E + SA LF + ID +++NA ++ A + EE + VN+ Sbjct: 69 MSKPEA----IKDSAAELFENRQIDILVNNAGIIHREK-AEDFPEENWQHVLNVNLNSLF 123 Query: 535 TLTRLLAPFMLDRGMGHFVVMSSAA---GKVPTPGQALYSASKHALNGYFASLRSELCTK 705 LT+L ML RG G + ++S G + P Y+ASKHA+ G S +E Sbjct: 124 ILTQLAGRHMLKRGHGKIINIASLLSFQGGILVPA---YTASKHAVAGLTKSFANEWAAS 180 Query: 706 GIKVTVVCPGPIETPESSGATSSSQRHSS-EKRVSVERCAELTIVAAT 846 GI+V + PG I T + +R+ KR+ R + + T Sbjct: 181 GIQVNAIAPGYISTANTKPIRDDEKRNEDILKRIPAGRWGQADDIGGT 228
>P50164:TRN2_HYONI Tropinone reductase 2 - Hyoscyamus niger (Henbane)| Length = 260 Score = 68.9 bits (167), Expect = 5e-11 Identities = 62/221 (28%), Positives = 100/221 (45%) Frame = +1 Query: 160 RDKVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVE 339 R ++G +TG SRGIG + + A+LGA + +RN++EL+ SK VE Sbjct: 4 RWNLEGCTALVTGGSRGIGYGIVEELANLGASVYTCSRNQKELDECLTQWRSK--GFNVE 61 Query: 340 VLPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVN 519 DLSS +S +E S ++ +++NA K A + T E +N Sbjct: 62 ASVCDLSS--RSEREEFMKTVSNHFHGKLNILVNNAGIVIYKE-AKDYTMEDYSHIMSIN 118 Query: 520 VFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELC 699 L+ L PF+ G+ V +SS +G P +A+Y A+K A++ L E Sbjct: 119 FEAAYHLSVLAHPFLKASERGNVVFISSISGASALPYEAVYGATKGAMDQLTRCLAFEWA 178 Query: 700 TKGIKVTVVCPGPIETPESSGATSSSQRHSSEKRVSVERCA 822 I+V V PG I T ++ + ++ ++RCA Sbjct: 179 KDNIRVNGVGPGVIATSMVEMTIQDPEQKENLDKL-IDRCA 218
>P41177:DHKR_STRCM Monensin polyketide synthase putative ketoacyl reductase -| Streptomyces cinnamonensis Length = 261 Score = 68.6 bits (166), Expect = 6e-11 Identities = 58/194 (29%), Positives = 92/194 (47%), Gaps = 3/194 (1%) Frame = +1 Query: 178 KVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDL 357 +V +TGA+ GIG + A+ G + L AR + ++ + + +++ +VL + Sbjct: 7 RVALVTGATSGIGLATARLLAAQGHLVFLGARTESDVIATVKALRNDGLEAEGQVLDV-- 64 Query: 358 SSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEE-TEEGLKATFKVNVFGTI 534 D S+ V +A + ID +++NA R G + T+E N+ Sbjct: 65 -RDGASVTAFVQAAVDRYGR--IDVLVNNAG--RSGGGVTADLTDELWDDVIDTNLNSVF 119 Query: 535 TLTR--LLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKG 708 +TR L M R G + ++S AGK A YSASKH + G+ +L +EL G Sbjct: 120 RMTRAVLTTGGMRTRERGRIINVASTAGKQGVVLGAPYSASKHGVVGFTKALGNELAPTG 179 Query: 709 IKVTVVCPGPIETP 750 I V VCPG +ETP Sbjct: 180 ITVNAVCPGYVETP 193
>P51976:DHI2_RABIT Corticosteroid 11-beta-dehydrogenase isozyme 2 - Oryctolagus| cuniculus (Rabbit) Length = 406 Score = 68.6 bits (166), Expect = 6e-11 Identities = 62/231 (26%), Positives = 103/231 (44%), Gaps = 7/231 (3%) Frame = +1 Query: 112 VTADGDFTLLSCGRPRRDKVDGKVVWITGASRGIGEVLSMQFASLGAKL---ILSARNKE 282 + A G L RP+R V + V ITG G G+ + + ++G + +L Sbjct: 61 LAAAGWIALSRLARPQRLPVATRAVLITGCDSGFGKETAKKLDAMGFTVLATVLEMNGPG 120 Query: 283 ELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERP 462 LE + ++++L MDL+ + + ++ +S G+ +++NA Sbjct: 121 ALE------LRACCSPRLKLLQMDLTKPA-DISRALEFTKAHTTSTGLWGLVNNAGHN-- 171 Query: 463 KRGALEETEEGLKATFK----VNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPG 630 + + E ATF+ VN FG + LT+ L P +L G V + S AG++P P Sbjct: 172 --DVVADVELSPVATFRNCMEVNFFGALELTKGLLP-LLHHSRGRIVTLGSPAGEMPYPC 228 Query: 631 QALYSASKHALNGYFASLRSELCTKGIKVTVVCPGPIETPESSGATSSSQR 783 A Y SK A+ + EL G+KV+V+ PG +T S + QR Sbjct: 229 LAAYGTSKAAMALLMDAFSCELLPWGVKVSVIQPGCFKTESVSNVSHWEQR 279
>Q8CQD2:BUTA_STAES Acetoin(diacetyl) reductase - Staphylococcus epidermidis (strain| ATCC 12228) Length = 257 Score = 68.6 bits (166), Expect = 6e-11 Identities = 56/191 (29%), Positives = 89/191 (46%), Gaps = 1/191 (0%) Frame = +1 Query: 178 KVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDL 357 K ITGA+ G+G+ ++ + A+ G ++L N+ L + K + D+ Sbjct: 3 KTAIITGAAGGLGKGIAERLANDGFNIVLQDINEALLLETEKEFKEK--GYQAVAYKSDV 60 Query: 358 SSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTIT 537 S +K +E+V A + F +D M++NA + LE EE L F +NVFGT+ Sbjct: 61 SK-KKEQEELVQFAVTEFGQ--LDVMVNNAGVDAVTP-ILEIGEEELSKLFNINVFGTLF 116 Query: 538 LTRLLA-PFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 714 + A F+ + G + S AG YSA+KH++ + + EL KGI Sbjct: 117 GIQAAANQFIKQKSKGKIINACSIAGHESYEVLGTYSATKHSVRSFTQTAAKELADKGIT 176 Query: 715 VTVVCPGPIET 747 V CPG +T Sbjct: 177 VNAYCPGVAKT 187
>Q5KEJ9:TSC10_CRYNE 3-ketodihydrosphingosine reductase TSC10 - Cryptococcus neoformans| (Filobasidiella neoformans) Length = 335 Score = 68.2 bits (165), Expect = 8e-11 Identities = 51/196 (26%), Positives = 91/196 (46%), Gaps = 4/196 (2%) Frame = +1 Query: 175 GKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMS-KHPDSKVEVLPM 351 GK +ITG S G+G+ L+ + GA + + R+ ++ E V + + P ++ + Sbjct: 35 GKHCYITGGSSGLGKALAERLVKQGAHVTIVGRDSKKAEGVVEELKAIAAPGQIIQCIAA 94 Query: 352 DLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPK---RGALEETEEGLKATFKVNV 522 DL+S S +H+A + DY+ A F RPK +E ++GL + V+ Sbjct: 95 DLTSPIAS-TNAIHAACKPHADQAPDYVYLCAGFSRPKLFVETTKQELKDGLDGVYWVSA 153 Query: 523 FGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCT 702 + ++++ R G + ++S V G + YS +K+AL G +LRSE+ Sbjct: 154 YTAHEACQMMSK---QRRTGKIIFVASFLSYVSFAGYSSYSPAKYALRGLSDALRSEMLL 210 Query: 703 KGIKVTVVCPGPIETP 750 I + + P I P Sbjct: 211 HNIDIHIFLPCGISGP 226
>P50200:HDHA_CLOSO NADP-dependent 7-alpha-hydroxysteroid dehydrogenase - Clostridium| sordellii Length = 267 Score = 68.2 bits (165), Expect = 8e-11 Identities = 54/222 (24%), Positives = 100/222 (45%), Gaps = 4/222 (1%) Frame = +1 Query: 163 DKVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEV 342 +K++ KV +T A+RGIG +++ A GA + + R E + I K+ + + + Sbjct: 2 NKLENKVALVTSATRGIGLASAIKLAQNGAIVYMGVRRLEATQE----ICDKYKEEGLIL 57 Query: 343 LPMDLSSDEKSL-KEVVHSAESLFSSAG-IDYMMHNAAFERPKRGA--LEETEEGLKATF 510 P+ + + KE++ +++ + G ID +++N RP++ + E+ F Sbjct: 58 KPVFFDAYNIDIYKEMI---DTIIKNEGKIDILVNNFGTGRPEKDLDLVNGDEDTFFELF 114 Query: 511 KVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRS 690 NV L++L+ P M++ G V +SS G +P + Y SK +N + Sbjct: 115 NYNVGSVYRLSKLIIPHMIENKGGSIVNISSVGGSIPDISRIGYGVSKSGVNNITKQIAI 174 Query: 691 ELCTKGIKVTVVCPGPIETPESSGATSSSQRHSSEKRVSVER 816 + GI+ V PG I T + + R S V + R Sbjct: 175 QYAKYGIRCNAVLPGLIATDAAMNSMPDEFRKSFLSHVPLNR 216
>P33207:FABG_ARATH 3-oxoacyl-[acyl-carrier-protein] reductase, chloroplast precursor -| Arabidopsis thaliana (Mouse-ear cress) Length = 319 Score = 68.2 bits (165), Expect = 8e-11 Identities = 51/192 (26%), Positives = 87/192 (45%), Gaps = 2/192 (1%) Frame = +1 Query: 166 KVDGKVVWITGASRGIGEVLSMQFASLGAKLILS-ARNKEELERVKHNIMSKHPDSKVEV 342 KV+ VV ITGASRGIG+ +++ G K++++ AR+ +E E V I + Sbjct: 73 KVESPVVVITGASRGIGKAIALALGKAGCKVLVNYARSAKEAEEVAKQIEEYGGQA---- 128 Query: 343 LPMDLSSDEKSLKEVVHSAESLFSSAG-IDYMMHNAAFERPKRGALEETEEGLKATFKVN 519 + D +V ++ G ID +++NA R + + +N Sbjct: 129 --ITFGGDVSKATDVDAMMKTALDKWGTIDVVVNNAGITRDTL-LIRMKQSQWDEVIALN 185 Query: 520 VFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELC 699 + G T+ M+ + G + +SS G + GQA Y+A+K + + + E Sbjct: 186 LTGVFLCTQAAVKIMMKKKRGRIINISSVVGLIGNIGQANYAAAKGGVISFSKTAAREGA 245 Query: 700 TKGIKVTVVCPG 735 ++ I V VVCPG Sbjct: 246 SRNINVNVVCPG 257
>Q27979:RDH1_BOVIN 11-cis retinol dehydrogenase - Bos taurus (Bovine)| Length = 318 Score = 67.8 bits (164), Expect = 1e-10 Identities = 50/192 (26%), Positives = 93/192 (48%), Gaps = 3/192 (1%) Frame = +1 Query: 184 VWITGASRGIGEVLSMQFASLGAKLI---LSARNKEELERVKHNIMSKHPDSKVEVLPMD 354 ++ITG G G +L+++ G +++ L+ E+L+RV S++ +D Sbjct: 31 IFITGCDSGFGRLLALRLDQRGFRVLASCLTPSGAEDLQRVA--------SSRLHTTLLD 82 Query: 355 LSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTI 534 ++ D +S+++ V E+ AG+ +++NA +T E + VN G I Sbjct: 83 VT-DPQSIRQAVKWVETHVGEAGLFGLVNNAGVAGIIGPTPWQTREDFQRVLNVNTLGPI 141 Query: 535 TLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 714 +T L P +L + G + ++S G++ G Y SK L + SLR ++ G++ Sbjct: 142 GVTLALLPLLL-QARGRVINITSVLGRLAANGGG-YCVSKFGLEAFSDSLRRDVAPFGVR 199 Query: 715 VTVVCPGPIETP 750 V++V PG TP Sbjct: 200 VSIVEPGFFRTP 211
>P50197:LINC_PSEPA 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase -| Pseudomonas paucimobilis (Sphingomonas paucimobilis) Length = 250 Score = 67.8 bits (164), Expect = 1e-10 Identities = 53/195 (27%), Positives = 88/195 (45%), Gaps = 1/195 (0%) Frame = +1 Query: 169 VDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLP 348 + GK + +TG GIG + GA + ++ N E E V K + ++ Sbjct: 4 LSGKTIIVTGGGSGIGRATVELLVASGANVPVADINDEAGEAVVATSGGKAAYFRCDI-- 61 Query: 349 MDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFG 528 + E+ +K +V A++L + G+D +NAA + E + E + + +NV G Sbjct: 62 ----AQEEDVKALV--AQTLAAFGGLDGSFNNAAIPQAGLPLAEVSLERFRQSMDINVTG 115 Query: 529 TITLTRLLAPFMLDRGM-GHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTK 705 T + M++RG G V +SAAG V P Y +KHA+ G ++ Sbjct: 116 TFLCMKYQILAMIERGTKGSIVNTASAAGVVGVPMHGEYVGAKHAVVGLTRVAAADYGKH 175 Query: 706 GIKVTVVCPGPIETP 750 GI+V + PG + TP Sbjct: 176 GIRVNALVPGAVRTP 190
>Q8K9J5:FABG_BUCAP 3-oxoacyl-[acyl-carrier-protein] reductase - Buchnera aphidicola| subsp. Schizaphis graminum Length = 244 Score = 67.8 bits (164), Expect = 1e-10 Identities = 47/194 (24%), Positives = 95/194 (48%) Frame = +1 Query: 166 KVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVL 345 K++ K +TGA++G+G+ ++++ + G ++I ++ + ++ + +K+ Sbjct: 2 KIEKKTALVTGANQGLGKEIAIKLSQKGIQVIGTSTTVDGVKTI-----NKYLKKNGFGF 56 Query: 346 PMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVF 525 +DL + L+++ + +S ID +++NA +E + K+N+ Sbjct: 57 ILDLKDTDSILEKMKEICQKKYS---IDILINNAGITSDNLLVYMSNKEW-ENVIKINLT 112 Query: 526 GTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTK 705 +++ + M+ + G V + S G + GQ YSASK L G+ SL E+ K Sbjct: 113 SVFYMSKSVIRSMIKKRYGRIVTIGSVIGYLGNRGQINYSASKSGLIGFHKSLALEVAQK 172 Query: 706 GIKVTVVCPGPIET 747 GI V +V PG I+T Sbjct: 173 GITVNIVSPGFIKT 186
>Q949M2:FABG4_BRANA 3-oxoacyl-[acyl-carrier-protein] reductase 4 - Brassica napus| (Rape) Length = 254 Score = 67.8 bits (164), Expect = 1e-10 Identities = 52/194 (26%), Positives = 96/194 (49%), Gaps = 4/194 (2%) Frame = +1 Query: 166 KVDGKVVWITGASRGIGEVLSMQFASLGAKLILS-ARNKEELERVKHNIMSKHPDSKVEV 342 KV+ VV +TGASRGIG+ +++ G K++++ AR+ +E E V I + + Sbjct: 11 KVESPVVVVTGASRGIGKAIALSLGKAGCKVLVNYARSAKEAEEVSKQI--EEYGGQAIT 68 Query: 343 LPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAA---FERPKRGALEETEEGLKATFK 513 D+S E + ++ +A + + ID +++NA R K+ +E + Sbjct: 69 FGGDVSK-EADVDAMMKTAVDKWGT--IDVVVNNAGDTLLIRMKKSQWDEVMD------- 118 Query: 514 VNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSE 693 +N+ G ++ M+ + G + ++S G + GQA Y+A+K + G+ + E Sbjct: 119 LNLTGVFLCSQAATKIMMKKRKGRIINIASVVGLIGNIGQANYAAAKAGVIGFSKTAARE 178 Query: 694 LCTKGIKVTVVCPG 735 ++ I V VVCPG Sbjct: 179 GASRNINVNVVCPG 192
>P50168:DHI2_SHEEP Corticosteroid 11-beta-dehydrogenase isozyme 2 - Ovis aries (Sheep)| Length = 427 Score = 67.8 bits (164), Expect = 1e-10 Identities = 58/216 (26%), Positives = 100/216 (46%), Gaps = 4/216 (1%) Frame = +1 Query: 112 VTADGDFTLLSCGRPRRDKVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELE 291 + A G L RP+R V + V ITG G G + + ++G ++ + + Sbjct: 61 LAATGWIVLSRLARPQRLPVATRAVLITGCDSGFGNATAKKLDAMGFTVLATVLDLNSPG 120 Query: 292 RVKHNIMSKHPDSKVEVLPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRG 471 ++ S++++L MDL+ + V+ + +S G+ +++NA + Sbjct: 121 ALELRACCS---SRLQLLQMDLTKPA-DISRVLEFTKVHTASTGLWGLVNNAG----QNI 172 Query: 472 ALEETEEGLKATFK----VNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQAL 639 + + E ATF+ VN FG + +T+ L P +L R G V +SS AG +P P A Sbjct: 173 FVADAELCPVATFRTCMEVNFFGALEMTKGLLP-LLRRSSGRIVTVSSPAGDMPFPCLAA 231 Query: 640 YSASKHALNGYFASLRSELCTKGIKVTVVCPGPIET 747 Y SK AL + EL G+KV+++ P +T Sbjct: 232 YGTSKAALALLMGNFSCELLPWGVKVSIILPACFKT 267
>Q5HKG6:BUTA_STAEQ Acetoin(diacetyl) reductase - Staphylococcus epidermidis (strain| ATCC 35984 / RP62A) Length = 257 Score = 67.8 bits (164), Expect = 1e-10 Identities = 55/191 (28%), Positives = 89/191 (46%), Gaps = 1/191 (0%) Frame = +1 Query: 178 KVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDL 357 K ITG++ G+G+ ++ + A+ G ++L N+ L + K + D+ Sbjct: 3 KTAIITGSAGGLGKGIAERLANDGFNIVLQDINEALLLETEKEFKEK--GYQAVAFKSDV 60 Query: 358 SSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTIT 537 S +K +E+V A + F +D M++NA + LE EE L F +NVFGT+ Sbjct: 61 SK-KKEQEELVQFAVTEFGQ--LDVMVNNAGVDAVTP-ILEIGEEELSKLFNINVFGTLF 116 Query: 538 LTRLLA-PFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 714 + A F+ + G + S AG YSA+KH++ + + EL KGI Sbjct: 117 GIQAAANQFIKQKSKGKIINACSIAGHESYEVLGTYSATKHSVRSFTQTAAKELADKGIT 176 Query: 715 VTVVCPGPIET 747 V CPG +T Sbjct: 177 VNAYCPGVAKT 187
>O18404:HCD2_DROME 3-hydroxyacyl-CoA dehydrogenase type-2 - Drosophila melanogaster| (Fruit fly) Length = 255 Score = 67.4 bits (163), Expect = 1e-10 Identities = 58/207 (28%), Positives = 92/207 (44%), Gaps = 13/207 (6%) Frame = +1 Query: 169 VDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLP 348 + V +TG + G+G + + A GA +IL+ +L K N ++K KV +P Sbjct: 2 IKNAVSLVTGGASGLGRATAERLAKQGASVILA-----DLPSSKGNEVAKELGDKVVFVP 56 Query: 349 MDLSSDEKSLKEVVHSAESLF-------SSAGIDYMMHNAAFERPKRGALEETEEGLKAT 507 +D++S EK + + +A+ F + AG + F + LE+ + Sbjct: 57 VDVTS-EKDVSAALQTAKDKFGRLDLTVNCAGTATAVKTFNFNKNVAHRLEDFQR----V 111 Query: 508 FKVNVFGTITLTRLLAPFM------LDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNG 669 +N GT + RL A M D G V +S A GQA YSASK A+ G Sbjct: 112 ININTVGTFNVIRLSAGLMGANEPNQDGQRGVIVNTASVAAFDGQIGQAAYSASKAAVVG 171 Query: 670 YFASLRSELCTKGIKVTVVCPGPIETP 750 + +L T+GI++ + PG TP Sbjct: 172 MTLPIARDLSTQGIRICTIAPGLFNTP 198
>P50199:GNO_GLUOX Gluconate 5-dehydrogenase - Gluconobacter oxydans (Gluconobacter| suboxydans) Length = 256 Score = 67.4 bits (163), Expect = 1e-10 Identities = 51/194 (26%), Positives = 93/194 (47%), Gaps = 1/194 (0%) Frame = +1 Query: 169 VDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLP 348 + G +TGASRGIG L+ A GA+++L+ RN E L+ + ++ + V Sbjct: 9 LSGARALVTGASRGIGLTLAKGLARYGAEVVLNGRNAESLDSAQSGFEAEGLKASTAVFD 68 Query: 349 MDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEE-TEEGLKATFKVNVF 525 + +D+ ++ + V + E ID +++NA +R R LEE + + NV Sbjct: 69 V---TDQDAVIDGVAAIER--DMGPIDILINNAGIQR--RAPLEEFSRKDWDDLMSTNVN 121 Query: 526 GTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTK 705 + + +A M+ RG G V + S ++ PG A Y+A+K A+ + ++ Sbjct: 122 AVFFVGQAVARHMIPRGRGKIVNICSVQSELARPGIAPYTATKGAVKNLTKGMATDWGRH 181 Query: 706 GIKVTVVCPGPIET 747 G+++ + PG T Sbjct: 182 GLQINGLAPGYFAT 195
>P55336:FABG_VIBHA 3-oxoacyl-[acyl-carrier-protein] reductase - Vibrio harveyi| Length = 244 Score = 67.4 bits (163), Expect = 1e-10 Identities = 52/225 (23%), Positives = 101/225 (44%) Frame = +1 Query: 169 VDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLP 348 ++GK+ +TGASRGIG ++ GA +I +A ++ + + + V Sbjct: 3 LEGKIALVTGASRGIGRAIAELLVERGATVIGTATSEGGAAAISEYLGENGKGLALNVT- 61 Query: 349 MDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFG 528 D+ S E +LK + ID +++NA R + ++ N+ Sbjct: 62 -DVESIEATLKTINDEC------GAIDILVNNAGITRDNL-LMRMKDDEWNDIINTNLTP 113 Query: 529 TITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKG 708 +++ + M+ + G + + S G + GQ Y+A+K + G+ S+ E+ ++G Sbjct: 114 IYRMSKAVLRGMMKKRAGRIINVGSVVGTMGNAGQTNYAAAKAGVIGFTKSMAREVASRG 173 Query: 709 IKVTVVCPGPIETPESSGATSSSQRHSSEKRVSVERCAELTIVAA 843 + V V PG IET + + A + QR ++ V R + +A+ Sbjct: 174 VTVNTVAPGFIET-DMTKALNDDQRAATLSNVPAGRLGDPREIAS 217
>Q5R9W5:WWOX_PONPY WW domain-containing oxidoreductase - Pongo pygmaeus (Orangutan)| Length = 414 Score = 67.0 bits (162), Expect = 2e-10 Identities = 63/202 (31%), Positives = 95/202 (47%), Gaps = 9/202 (4%) Frame = +1 Query: 121 DGDFTLLSCGRPRRDKVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVK 300 DG T L + R GKVV +TGA+ GIG + FA GA +IL+ RN Sbjct: 108 DGSTTALEILQGR--DFTGKVVVVTGANSGIGFETAKSFALHGAHVILACRNMARASEAV 165 Query: 301 HNIMSKHPDSKVEVLPMDLSSDEKSLKEVVHSAESL-FSSAGIDYMMHNAA-FERPKRGA 474 I+ + +KVE + +DL+ L+ V H AE+ + + ++ NAA F P Sbjct: 166 SRILEEWHKAKVEAVTLDLA----LLRSVQHFAEAFKAKNVPLHVLVCNAATFALP---- 217 Query: 475 LEETEEGLKATFKVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQAL----Y 642 T++GL+ TF+VN G L +LL + +V+SS + + +L + Sbjct: 218 WSLTKDGLETTFQVNHLGHFYLVQLLQDVLCRSAPARVIVVSSESHRFTDINDSLGKLDF 277 Query: 643 SASKHALNGYFASL---RSELC 699 S N Y+A L RS+LC Sbjct: 278 SRLSPTKNDYWAMLAYNRSKLC 299
>Q9NZC7:WWOX_HUMAN WW domain-containing oxidoreductase - Homo sapiens (Human)| Length = 414 Score = 67.0 bits (162), Expect = 2e-10 Identities = 58/184 (31%), Positives = 89/184 (48%), Gaps = 9/184 (4%) Frame = +1 Query: 175 GKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMD 354 GKVV +TGA+ GIG + FA GA +IL+ RN I+ + +KVE + +D Sbjct: 124 GKVVVVTGANSGIGFETAKSFALHGAHVILACRNMARASEAVSRILEEWHKAKVEAMTLD 183 Query: 355 LSSDEKSLKEVVHSAESL-FSSAGIDYMMHNAA-FERPKRGALEETEEGLKATFKVNVFG 528 L+ L+ V H AE+ + + ++ NAA F P T++GL+ TF+VN G Sbjct: 184 LA----LLRSVQHFAEAFKAKNVPLHVLVCNAATFALP----WSLTKDGLETTFQVNHLG 235 Query: 529 TITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQAL----YSASKHALNGYFASL---R 687 L +LL + +V+SS + + +L +S N Y+A L R Sbjct: 236 HFYLVQLLQDVLCRSAPARVIVVSSESHRFTDINDSLGKLDFSRLSPTKNDYWAMLAYNR 295 Query: 688 SELC 699 S+LC Sbjct: 296 SKLC 299
>P50205:PHBB_RHIME Acetoacetyl-CoA reductase - Rhizobium meliloti (Sinorhizobium| meliloti) Length = 241 Score = 67.0 bits (162), Expect = 2e-10 Identities = 54/190 (28%), Positives = 81/190 (42%) Frame = +1 Query: 178 KVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDL 357 +V +TG SRGIG + + + G K+ + +E + +S + V D+ Sbjct: 3 RVALVTGGSRGIGAAICVALKAAGYKVAANYAGNDERAKAFEQ------ESGIPVYKWDV 56 Query: 358 SSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTIT 537 SS + + + L +D +++NA R + T E N+ G Sbjct: 57 SSYQACVDGIARVEADL---GPVDILVNNAGITRDAMFH-KMTPEQWGEVIGTNLTGVFN 112 Query: 538 LTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIKV 717 +T L M DRG G V +SS G+ GQ YSA+K G +L E KGI V Sbjct: 113 MTHPLWSGMRDRGFGRIVNISSINGQKGQMGQVNYSAAKAGDLGLTKALAQEGAAKGITV 172 Query: 718 TVVCPGPIET 747 +CPG I T Sbjct: 173 NAICPGYIGT 182
>Q9PKF7:FABG_CHLMU 3-oxoacyl-[acyl-carrier-protein] reductase - Chlamydia muridarum| Length = 248 Score = 67.0 bits (162), Expect = 2e-10 Identities = 53/199 (26%), Positives = 93/199 (46%) Frame = +1 Query: 178 KVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDL 357 K +TG SRGIG ++ FA GA + + N+E + ++ K SKV +D+ Sbjct: 8 KAAIVTGGSRGIGFGIAKLFAEHGANVQIWGINEEAGKSAAQDLSDK-TGSKVSFALVDV 66 Query: 358 SSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTIT 537 S ++ +V + L ID +++NA R + +EE + N+ Sbjct: 67 SKNDMVSAQV---QKFLAEYGTIDVVVNNAGITRDSL-LMRMSEEEWSSVIDTNLGSIYN 122 Query: 538 LTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIKV 717 + + M+ G V +SS G +PGQ Y+A+K + G+ +L E+ +K I+V Sbjct: 123 VCSAVIRPMIKARSGAIVNISSIVGLRGSPGQTNYAAAKAGIIGFSKALSKEVGSKNIRV 182 Query: 718 TVVCPGPIETPESSGATSS 774 + PG I+T + G + + Sbjct: 183 NCIAPGFIDTDMTKGLSDN 201
>P80869:DHG2_BACSU Glucose 1-dehydrogenase 2 - Bacillus subtilis| Length = 258 Score = 67.0 bits (162), Expect = 2e-10 Identities = 57/238 (23%), Positives = 105/238 (44%), Gaps = 6/238 (2%) Frame = +1 Query: 175 GKVVWITGASRGIGEVLSMQFASLGAKLILSARNK-----EELERVKHNIMSKHPDSKVE 339 GK +TG+S+GIG+ ++ +F ++++ + E LE +K N K Sbjct: 7 GKTAIVTGSSKGIGKAIAERFGKEKMNVVVNYHSDPSGADETLEIIKQN------GGKAV 60 Query: 340 VLPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVN 519 + D+S +E ++ ++ +A F + +D M++N+ F + E + E + VN Sbjct: 61 SVEADVSKEE-GIQALLDTALEHFGT--LDVMVNNSGFNGVEAMPHEMSLEDWQRVIDVN 117 Query: 520 VFGTITLTRLLAPFMLDRGM-GHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSEL 696 V GT + M+ + G+ + +SS ++P P YS SK + +L Sbjct: 118 VTGTFLGAKAALNHMMKNNIKGNVLNISSVHQQIPRPVNVQYSTSKGGIKMMTETLALNY 177 Query: 697 CTKGIKVTVVCPGPIETPESSGATSSSQRHSSEKRVSVERCAELTIVAATHGLKEAWI 870 KGI+V + PG I T + R K++ ++ + VAA AW+ Sbjct: 178 ADKGIRVNAIAPGTIATESNVDTKKEESRQKQLKKIPMKAFGKPEEVAAA----AAWL 231
>Q91X52:DCXR_MOUSE L-xylulose reductase - Mus musculus (Mouse)| Length = 244 Score = 67.0 bits (162), Expect = 2e-10 Identities = 63/229 (27%), Positives = 115/229 (50%), Gaps = 5/229 (2%) Frame = +1 Query: 175 GKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMD 354 G+ +TGA +GIG + + GA+++ +R +E+L+ +++ + P VE + +D Sbjct: 7 GRRALVTGAGKGIGRSTVLALKAAGAQVVAVSRTREDLD----DLVRECPG--VEPVCVD 60 Query: 355 LSSDEKSLKEVVHSAESLFSSAG-IDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGT 531 L+ E + E S+ G +D +++NAA + LE T+E +F VN+ Sbjct: 61 LADWE--------ATEQALSNVGPVDLLVNNAAVAL-LQPFLEVTKEACDTSFNVNLRAV 111 Query: 532 ITLTRLLAPFMLDRGM-GHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKG 708 I +++++A M+ RG+ G V +SS A + +Y ++K AL+ + EL Sbjct: 112 IQVSQIVAKGMIARGVPGAIVNVSSQASQRALTNHTVYCSTKGALDMLTKMMALELGPHK 171 Query: 709 IKVTVVCPGPIETPESSGATSSSQRHSSE---KRVSVERCAELTIVAAT 846 I+V V P + TP G T+ S H ++ R+ + + AE+ V T Sbjct: 172 IRVNAVNPTVVMTP--MGRTNWSDPHKAKAMLDRIPLGKFAEVENVVDT 218
>Q48436:BUDC_KLEPN Acetoin(diacetyl) reductase - Klebsiella pneumoniae| Length = 256 Score = 67.0 bits (162), Expect = 2e-10 Identities = 59/233 (25%), Positives = 102/233 (43%), Gaps = 11/233 (4%) Frame = +1 Query: 178 KVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDL 357 KV +TGA +GIG+ ++++ G + ++ N + V I + + +D+ Sbjct: 3 KVALVTGAGQGIGKAIALRLVKDGFAVAIADYNDATAKAVASEI--NQAGGRAMAVKVDV 60 Query: 358 SSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTIT 537 S ++ V + ++L G D +++NA P T E + + +NV G I Sbjct: 61 SDRDQVFAAVEQARKTL---GGFDVIVNNAGVA-PSTPIESITPEIVDKVYNINVKGVIW 116 Query: 538 -LTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 714 + + F + G + S AG V P A+YS+SK A+ G + +L GI Sbjct: 117 GIQAAVEAFKKEGHGGKIINACSQAGHVGNPELAVYSSSKFAVRGLTQTAARDLAPLGIT 176 Query: 715 VTVVCPGPIETP----------ESSGATSSSQRHSSEKRVSVERCAELTIVAA 843 V CPG ++TP E++G KR+++ R +E VAA Sbjct: 177 VNGYCPGIVKTPMWAEIDRQVSEAAGKPLGYGTAEFAKRITLGRLSEPEDVAA 229
>P40471:AYR1_YEAST NADPH-dependent 1-acyldihydroxyacetone phosphate reductase -| Saccharomyces cerevisiae (Baker's yeast) Length = 297 Score = 67.0 bits (162), Expect = 2e-10 Identities = 55/192 (28%), Positives = 95/192 (49%), Gaps = 2/192 (1%) Frame = +1 Query: 178 KVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDL 357 K+ +TGAS GIG ++ + A G + AR E + + + + + ++ +D+ Sbjct: 10 KIAVVTGASGGIGYEVTKELARNGYLVYACARRLEPMAQ----LAIQFGNDSIKPYKLDI 65 Query: 358 SSDEKSLKEVVHSAESLFSSA--GIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGT 531 S E E+V + L ++ G +++N A + AL+ T+ ++ FKVNVFG Sbjct: 66 SKPE----EIVTFSGFLRANLPDGKLDLLYNNAGQSCTFPALDATDAAVEQCFKVNVFGH 121 Query: 532 ITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 711 I + R L+ F++ + G V S AG V P ++YSASK A++ Y L E+ + Sbjct: 122 INMCRELSEFLI-KAKGTIVFTGSLAGVVSFPFGSIYSASKAAIHQYARGLHLEMKPFNV 180 Query: 712 KVTVVCPGPIET 747 +V G + T Sbjct: 181 RVINAITGGVAT 192
>P55541:Y4LA_RHISN Uncharacterized short-chain type dehydrogenase/reductase y4lA -| Rhizobium sp. (strain NGR234) Length = 278 Score = 66.6 bits (161), Expect = 2e-10 Identities = 58/218 (26%), Positives = 104/218 (47%), Gaps = 4/218 (1%) Frame = +1 Query: 163 DKVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEV 342 ++ +GKV +TGA GIG+ ++ A G +++++ + I ++ ++ Sbjct: 2 ERFEGKVAVVTGAGAGIGKACALAIAREGGRVVVADLDGSAAIACTAQIAAEAGNALA-- 59 Query: 343 LPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFER--PKRGALEETEEGL-KATFK 513 + MD++ D +++ + +AE F G+D +++NA+ P+ A+ + + + T Sbjct: 60 MAMDIA-DAQAVAALFETAERHFG--GVDLLVNNASAMHLTPRDRAILDLDLAVWDQTMA 116 Query: 514 VNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSE 693 N+ GT+ R P M+ RG G V MSS G Q Y+ SK A+N ASL ++ Sbjct: 117 TNLRGTLLCCRQAIPRMIARGGGAIVNMSSCQGLSGDTAQTSYAVSKAAMNMLSASLATQ 176 Query: 694 LCTKGIKVTVVCPGPIETPE-SSGATSSSQRHSSEKRV 804 I+ V PG I T + QRH S ++ Sbjct: 177 YGHAQIRCNAVAPGLIMTERLLAKLDKCMQRHLSRHQL 214
>P70720:FABG_ACTAC 3-oxoacyl-[acyl-carrier-protein] reductase - Actinobacillus| actinomycetemcomitans (Haemophilus actinomycetemcomitans) Length = 242 Score = 66.2 bits (160), Expect = 3e-10 Identities = 54/193 (27%), Positives = 95/193 (49%), Gaps = 3/193 (1%) Frame = +1 Query: 178 KVVWITGASRGIGEVLSMQFASLGAKLILSARNK-EELERVKHNIMSKHPDSKVEVLPMD 354 + + ITG+SRGIG+ ++++ A G +++ R++ EE E V + +++V L D Sbjct: 3 ETILITGSSRGIGKAIALRLAQAGFDIVVHCRSRIEEAEAVAQAVRELGQNARV--LQFD 60 Query: 355 LSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKR-GALEETEEGLKATFKVNVFGT 531 +S ++ ++ E+ + G+ + NA R AL T+E + N+ G Sbjct: 61 VSCRSEAADKLTADVEAHGAYYGV---VLNAGLTRDNAFPAL--TDEDWDRVLRTNLDGF 115 Query: 532 ITLTR-LLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKG 708 + ++ P + R G V ++S +G + GQ YSASK + G +L EL + Sbjct: 116 YNVLHPIMMPMIRRRKAGRIVCITSVSGLIGNRGQVNYSASKAGIIGAAKALAVELAKRK 175 Query: 709 IKVTVVCPGPIET 747 I V V PG I+T Sbjct: 176 ITVNCVAPGLIDT 188
>Q3U0B3:DHR11_MOUSE Dehydrogenase/reductase SDR family member 11 precursor - Mus| musculus (Mouse) Length = 260 Score = 66.2 bits (160), Expect = 3e-10 Identities = 58/201 (28%), Positives = 89/201 (44%), Gaps = 11/201 (5%) Frame = +1 Query: 178 KVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDL 357 ++ +TGAS GIG ++ G K++ AR +E + S + DL Sbjct: 12 RLALVTGASGGIGAAVARALVQQGLKVVGCARTVGNIEELAAECKSAGYPGTLIPYRCDL 71 Query: 358 SSDEKSLKEVVHSAESLFSS-----AGIDYMMHNAAFERPKRGALEETEEGLKATFKVNV 522 S++E L S+FS+ +G+D ++NA RP L + G K F VNV Sbjct: 72 SNEEDIL--------SMFSAVRSQHSGVDICINNAGMARPDT-LLSGSTSGWKDMFNVNV 122 Query: 523 FGTITLTRLLAPFMLDRGM--GHFVVMSSAAGKVPTPGQAL--YSASKHALNGYFASLRS 690 TR M +R + GH + ++S G P + YSA+K+A+ LR Sbjct: 123 LALSICTREAYQSMKERNIDDGHIININSMCGHRVPPQSVIHFYSATKYAVTALTEGLRQ 182 Query: 691 EL--CTKGIKVTVVCPGPIET 747 EL I+ T + PG +ET Sbjct: 183 ELLEAQTHIRATCISPGLVET 203
>Q6P3L6:DH12A_DANRE Estradiol 17-beta-dehydrogenase 12-A - Danio rerio (Zebrafish)| (Brachydanio rerio) Length = 319 Score = 66.2 bits (160), Expect = 3e-10 Identities = 63/256 (24%), Positives = 115/256 (44%), Gaps = 6/256 (2%) Frame = +1 Query: 175 GKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMD 354 GK +TGA+ GIG+ + + A G ++L +R++E+L+ V ++ S + KVE + Sbjct: 56 GKWAVVTGATDGIGKSYAEELARRGFSMMLISRSQEKLDDVAKSLESTY---KVETKTIA 112 Query: 355 LSSDEKSLKEVVHSAES------LFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKV 516 + + + + + L ++ GI Y P + E + V Sbjct: 113 VDFSQIDVYPKIEKGLAGLEIGILVNNVGISYSYPEFFLHIP------DLENFITTMINV 166 Query: 517 NVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSEL 696 N+ +TRL+ P M R G + +SSA+G P P +YS++K ++ + L++E Sbjct: 167 NITSVCQMTRLVLPRMEARAKGVILNISSASGMFPVPLLTIYSSTKAFVDFFSRGLQTEY 226 Query: 697 CTKGIKVTVVCPGPIETPESSGATSSSQRHSSEKRVSVERCAELTIVAATHGLKEAWISY 876 KGI + V P + T + + + + E+ V+ AEL V GL++ Y Sbjct: 227 KCKGIIIQSVLPFFVATKMTKIRKPTLDKPTPERYVA----AELNTV----GLQDQTNGY 278 Query: 877 QPVLAVMYVVQYMPTI 924 P + +V + I Sbjct: 279 FPHAVMGWVTTILAPI 294
>P50161:VER1_ASPPA Versicolorin reductase - Aspergillus parasiticus| Length = 262 Score = 65.9 bits (159), Expect = 4e-10 Identities = 58/197 (29%), Positives = 94/197 (47%), Gaps = 3/197 (1%) Frame = +1 Query: 166 KVDGKVVWITGASRGIGEVLSMQFASLGAKLILS-ARNKEELERVKHNIMSKHPDSKVEV 342 ++DGKV +TGA RGIG +++ GAK++++ A ++E E+V I + D+ Sbjct: 6 RLDGKVALVTGAGRGIGAAIAVALGERGAKVVVNYAHSREAAEKVVEQIKANGTDA--IA 63 Query: 343 LPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEE-TEEGLKATFKVN 519 + D+ E + K + AE++ +D + NA G L++ T E F+VN Sbjct: 64 IQADVGDPEATAKLM---AETVRHFGYLDIVSSNAGI--VSFGHLKDVTPEEFDRVFRVN 118 Query: 520 VFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVP-TPGQALYSASKHALNGYFASLRSEL 696 G + R M R G ++ SS V P A+YS SK A++ + + + Sbjct: 119 TRGQFFVAREAYRHM--REGGRIILTSSNTACVKGVPKHAVYSGSKGAIDTFVRCMAIDC 176 Query: 697 CTKGIKVTVVCPGPIET 747 K I V V PG I+T Sbjct: 177 GDKKITVNAVAPGAIKT 193
>P50160:TS2_MAIZE Sex determination protein tasselseed-2 - Zea mays (Maize)| Length = 336 Score = 65.9 bits (159), Expect = 4e-10 Identities = 54/205 (26%), Positives = 90/205 (43%), Gaps = 6/205 (2%) Frame = +1 Query: 154 PRRDKVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSK 333 P ++DGKV +TG +RGIGE + FA GA+++++ +++ ++ + Sbjct: 48 PMPKRLDGKVAIVTGGARGIGEAIVRLFAKHGARVVIA-----DIDDAAGEALASALGPQ 102 Query: 334 VEVLPMDLSSDEKSLKEVVHSAESLFSSAG--IDYMMHNAAF----ERPKRGALEETEEG 495 V + D+S ++ +V + + S G +D +NA R R L Sbjct: 103 VSFVRCDVSVED----DVRRAVDWALSRHGGRLDVYCNNAGVLGRQTRAARSILSFDAAE 158 Query: 496 LKATFKVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYF 675 +VN G + A M R G V ++S A + G Y+ASKHA+ G Sbjct: 159 FDRVLRVNALGAALGMKHAARAMAPRRAGSIVSVASVAAVLGGLGPHAYTASKHAIVGLT 218 Query: 676 ASLRSELCTKGIKVTVVCPGPIETP 750 + EL G++V V P + TP Sbjct: 219 KNAACELRAHGVRVNCVSPFGVATP 243
>P50170:RDH2_RAT Retinol dehydrogenase 2 - Rattus norvegicus (Rat)| Length = 317 Score = 65.9 bits (159), Expect = 4e-10 Identities = 57/220 (25%), Positives = 105/220 (47%), Gaps = 2/220 (0%) Frame = +1 Query: 124 GDFTLLSCGRPRR--DKVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERV 297 G + LL R R+ + K V+ITG G G +L+ Q G +++ + ++ E++ Sbjct: 10 GLWNLLRLFRERKVVSHLQDKYVFITGCDSGFGNLLARQLDRRGMRVLAACLTEKGAEQL 69 Query: 298 KHNIMSKHPDSKVEVLPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGAL 477 + SK D ++E + +D++ E S+ + + G+ +++NA Sbjct: 70 R----SKTSD-RLETVILDVTKTE-SIVAATQWVKERVGNTGLWGLVNNAGISGHLGPNE 123 Query: 478 EETEEGLKATFKVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKH 657 ++ + + VN+ G I +T P ++ + G V ++S AG++ G Y SK+ Sbjct: 124 WMNKQNIASVLDVNLLGMIEVTLSTVP-LVRKARGRVVNVASIAGRLSFCGGG-YCISKY 181 Query: 658 ALNGYFASLRSELCTKGIKVTVVCPGPIETPESSGATSSS 777 + + SLR EL G+KV +V PG T ++G T SS Sbjct: 182 GVEAFSDSLRRELSYFGVKVAIVEPGFFRTDVTNGVTLSS 221
>P22414:FOX2_CANTR Peroxisomal hydratase-dehydrogenase-epimerase - Candida tropicalis| (Yeast) Length = 906 Score = 65.9 bits (159), Expect = 4e-10 Identities = 52/188 (27%), Positives = 93/188 (49%), Gaps = 3/188 (1%) Frame = +1 Query: 178 KVVWITGASRGIGEVLSMQFASLGAKLILSARNK--EELERVKHNIMSKHPDSKVEVLPM 351 KVV ITGA G+G+ + FA GAK++++ + ++ +K PD Sbjct: 323 KVVLITGAGAGLGKEYAKWFAKYGAKVVVNDFKDATKTVDEIKAAGGEAWPDQH------ 376 Query: 352 DLSSDEKSL-KEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFG 528 D++ D +++ K V+ + ID +++NA R + A +E + +V++ G Sbjct: 377 DVAKDSEAIIKNVIDKYGT------IDILVNNAGILRDRSFAKMSKQEW-DSVQQVHLIG 429 Query: 529 TITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKG 708 T L+RL P+ +++ G + ++S +G GQA YS+SK + G ++ E Sbjct: 430 TFNLSRLAWPYFVEKQFGRIINITSTSGIYGNFGQANYSSSKAGILGLSKTMAIEGAKNN 489 Query: 709 IKVTVVCP 732 IKV +V P Sbjct: 490 IKVNIVAP 497 Score = 60.8 bits (146), Expect = 1e-08 Identities = 55/194 (28%), Positives = 89/194 (45%), Gaps = 9/194 (4%) Frame = +1 Query: 178 KVVWITGASRGIGEVLSMQFASLGAKLILS---------ARNKEELERVKHNIMSKHPDS 330 KVV ITGA G+G+ S++FA LGAK++++ N + + V I+ K+ Sbjct: 9 KVVIITGAGGGLGKYYSLEFAKLGAKVVVNDLGGALNGQGGNSKAADVVVDEIV-KNGGV 67 Query: 331 KVEVLPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATF 510 V L D ++V +A F + + +++NA R + TE+ K Sbjct: 68 AVADYNNVLDGD-----KIVETAVKNFGT--VHVIINNAGILR-DASMKKMTEKDYKLVI 119 Query: 511 KVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRS 690 V++ G +T+ P+ + G V SS AG GQA Y+++K AL G+ +L Sbjct: 120 DVHLNGAFAVTKAAWPYFQKQKYGRIVNTSSPAGLYGNFGQANYASAKSALLGFAETLAK 179 Query: 691 ELCTKGIKVTVVCP 732 E IK + P Sbjct: 180 EGAKYNIKANAIAP 193
>P15047:ENTA_ECOLI 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase - Escherichia coli| Length = 248 Score = 65.9 bits (159), Expect = 4e-10 Identities = 56/194 (28%), Positives = 87/194 (44%), Gaps = 3/194 (1%) Frame = +1 Query: 175 GKVVWITGASRGIGEVLSMQFASLGAKLI-LSARNKEELERVKHNIMSKHPDSKVEVLPM 351 GK VW+TGA +GIG ++ F GAK+ +E +M ++V + Sbjct: 5 GKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQVCQ 64 Query: 352 DLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEE-TEEGLKATFKVNVFG 528 L ++ + L +V++A L + GA ++ ++E + TF VNV G Sbjct: 65 RLLAETERLDALVNAAGIL------------------RMGATDQLSKEDWQQTFAVNVGG 106 Query: 529 TITL-TRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTK 705 L + + F RG G V ++S A P G + Y ASK AL S+ EL Sbjct: 107 AFNLFQQTMNQFRRQRG-GAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGS 165 Query: 706 GIKVTVVCPGPIET 747 G++ VV PG +T Sbjct: 166 GVRCNVVSPGSTDT 179
>O16925:DHBY_CAEEL Putative steroid dehydrogenase tag-57 - Caenorhabditis elegans| Length = 314 Score = 65.9 bits (159), Expect = 4e-10 Identities = 50/189 (26%), Positives = 88/189 (46%), Gaps = 3/189 (1%) Frame = +1 Query: 190 ITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSS-D 366 +TGA+ GIG ++ A G + L +R K +L + K I++K+ D +V D + Sbjct: 58 VTGATDGIGRSYALDLARRGFNIFLISRTKSKLVKTKKQILNKYSDIEVRYAICDFTRVS 117 Query: 367 EKSLKEVVHSAESLFSSAGIDYMMHNA--AFERPKRGALEETEEGLKATFKVNVFGTITL 540 + K ++HS + I +++N F+ P+ L E G+ V + L Sbjct: 118 YEDYKRLLHS----LNEVDIGILINNVGMCFDNPE--VLHRVEGGIDTLTNVINVNILPL 171 Query: 541 TRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIKVT 720 T + P M+ R G V + SAAG + ++YSA+K + + + L+ E +GI Sbjct: 172 TAGILPQMMARKSGIIVNIGSAAGSIHMAKWSVYSATKKYIEWFTSILQKEYENEGIICQ 231 Query: 721 VVCPGPIET 747 + P + T Sbjct: 232 TITPLLVST 240
>O88736:DHB7_MOUSE 3-keto-steroid reductase - Mus musculus (Mouse)| Length = 334 Score = 65.9 bits (159), Expect = 4e-10 Identities = 64/235 (27%), Positives = 101/235 (42%), Gaps = 40/235 (17%) Frame = +1 Query: 178 KVVWITGASRGIGEVLSMQFASLG--AKLILSARNKEELERVKHNIMSKHPDSKVEVLPM 351 KVV ITGAS GIG L + + L L+ RN + V+ +++ HP ++V ++ M Sbjct: 3 KVVLITGASSGIGLALCGRLLAEDDDLHLCLACRNLSKARAVRDTLLASHPSAEVSIVQM 62 Query: 352 DLSSDEKSLKEVVHSAESLFSS-AGIDYMMHNAA----------------FER------- 459 D+S SL+ VV AE + +DY+ NA F R Sbjct: 63 DVS----SLQSVVRGAEEVKQKFQRLDYLYLNAGILPNPQFNLKAFFCGIFSRNVIHMFT 118 Query: 460 PKRGALEE----TEEGLKATFKVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVP-- 621 G L + T +GL+ F+ N+FG L R L P + ++ +S+ Sbjct: 119 TAEGILTQNDSVTADGLQEVFETNLFGHFILIRELEPLLCHADNPSQLIWTSSRNAKKAN 178 Query: 622 --------TPGQALYSASKHALNGYFASLRSELCTKGIKVTVVCPGPIETPESSG 762 + G YS+SK+A + +L KG+ +V+CPG + T + G Sbjct: 179 FSLEDIQHSKGPEPYSSSKYATDLLNVALNRNFNQKGLYSSVMCPGVVMTNMTYG 233
>Q9X6U2:BDHA_RALEH D-beta-hydroxybutyrate dehydrogenase - Ralstonia eutropha (strain| ATCC 17699 / H16 / DSM 428 / Stanier 337) (Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)) Length = 258 Score = 65.9 bits (159), Expect = 4e-10 Identities = 49/195 (25%), Positives = 92/195 (47%), Gaps = 1/195 (0%) Frame = +1 Query: 169 VDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLP 348 ++GK +TG++ GIG ++ A+ GA +I++ + + K I +V Sbjct: 2 LNGKTALVTGSTSGIGLGIAKALAAQGANIIVNGFG--DADAAKAEIAQAGQGIRVGYHG 59 Query: 349 MDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEE-TEEGLKATFKVNVF 525 D+S + +++++ A+S F G D +++NA + A+E+ E A +N+ Sbjct: 60 ADMSKAAE-IEDMMRYAQSDFG--GADILVNNAGIQHV--AAIEDFPPERWDAIIAINLT 114 Query: 526 GTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTK 705 TRL P M + G + ++S G V + ++ Y A+KH + G+ E Sbjct: 115 SAFHTTRLALPGMKQKDWGRIINVASTHGLVASAQKSAYVAAKHGIVGFTKVTALETAQT 174 Query: 706 GIKVTVVCPGPIETP 750 G+ +CPG + TP Sbjct: 175 GVTANAICPGWVLTP 189
>Q5F389:WWOX_CHICK WW domain-containing oxidoreductase - Gallus gallus (Chicken)| Length = 414 Score = 65.5 bits (158), Expect = 5e-10 Identities = 62/201 (30%), Positives = 100/201 (49%), Gaps = 8/201 (3%) Frame = +1 Query: 121 DGDFTLLSCGRPRRDKVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVK 300 DG+ T + + R + GKV+ ITGA+ GIG + FA GA +IL+ RN Sbjct: 108 DGNSTAMEILQGR--DLSGKVIIITGANSGIGFETAKSFALHGAYVILACRNMSRGNDAV 165 Query: 301 HNIMSKHPDSKVEVLPMDLSSDEKSLKEVVHSAESLFS-SAGIDYMMHNAAFERPKRGAL 477 I+ + +KVE + +DL+ SL+ V + AE+ S + + ++ NAA + Sbjct: 166 QRILEEWHKAKVEAMTLDLA----SLRSVQNFAEAFKSKNMPLHILVCNAAI---FGSSW 218 Query: 478 EETEEGLKATFKVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKV----PTPGQALYS 645 TE+GL++TF+VN G L +LL + VV+SS + + + G+ +S Sbjct: 219 CLTEDGLESTFQVNHLGHFYLVQLLEDILRRSSPARVVVVSSESHRFTEIKDSSGKLDFS 278 Query: 646 ASKHALNGYFASL---RSELC 699 + Y+A L RS+LC Sbjct: 279 LLSPSKKEYWAMLAYNRSKLC 299
>Q8U8I2:SDH_AGRT5 Serine 3-dehydrogenase - Agrobacterium tumefaciens (strain C58 /| ATCC 33970) Length = 249 Score = 65.5 bits (158), Expect = 5e-10 Identities = 59/245 (24%), Positives = 104/245 (42%) Frame = +1 Query: 184 VWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSS 363 + ITGA+ G G+ + +F G K+I + R E LE + + ++ + Sbjct: 5 ILITGATSGFGQATARRFVKEGWKVIGTGRRAERLEALAAELGQAFHGIAFDI------T 58 Query: 364 DEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLT 543 DE + ++ + + F ID +++NA A + + + N+ G + +T Sbjct: 59 DEDATEKALAALPDGFRD--IDILVNNAGLALGTAPAPQVALKDWQTMVDTNITGLLNIT 116 Query: 544 RLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIKVTV 723 L P ++ + G V +SS A P G +Y +K L + LRS+L KG++VT Sbjct: 117 HHLLPTLIKQ-KGIVVNLSSVAAHYPYLGGNVYGGTKAFLRQFSLGLRSDLHGKGVRVTS 175 Query: 724 VCPGPIETPESSGATSSSQRHSSEKRVSVERCAELTIVAATHGLKEAWISYQPVLAVMYV 903 + PG ET + T +Q S V I + W++ QP + Sbjct: 176 IEPGMCETEFTLVRTGGNQEASDNLYKGVNPITADDIANTIY-----WVASQPKHININS 230 Query: 904 VQYMP 918 ++ MP Sbjct: 231 LELMP 235
>P57432:FABG_BUCAI 3-oxoacyl-[acyl-carrier-protein] reductase - Buchnera aphidicola| subsp. Acyrthosiphon pisum (Acyrthosiphon pisum symbiotic bacterium) Length = 244 Score = 65.5 bits (158), Expect = 5e-10 Identities = 48/196 (24%), Positives = 96/196 (48%), Gaps = 3/196 (1%) Frame = +1 Query: 169 VDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLP 348 ++ + +ITGA++GIG+ ++ + G ++I ++ ++ ++R+ + + + Sbjct: 3 INRQTAFITGANQGIGKAIAKKLIKKGIQVIGTSTTEDGVKRINDYLEGNGFGFVLNLKN 62 Query: 349 MDLSSDE-KSLKEVVHSAESLFSSAGI--DYMMHNAAFERPKRGALEETEEGLKATFKVN 519 +D +++ + + + HS + L ++AGI D ++ N ++ TE K N Sbjct: 63 IDSITEKIQEIYKKKHSIDILINNAGIKEDNLLVN----------MKSTE--WDDVIKTN 110 Query: 520 VFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELC 699 + L + + M+ + G + + S GQ YSASK L G+ SL E+ Sbjct: 111 LSSVFHLVKSVIRSMIKKRQGRIITIGSVIAYTGNKGQVNYSASKSGLIGFHKSLALEVA 170 Query: 700 TKGIKVTVVCPGPIET 747 +KGI V +V PG I+T Sbjct: 171 SKGITVNIVSPGLIKT 186
>P50233:DHI2_RAT Corticosteroid 11-beta-dehydrogenase isozyme 2 - Rattus norvegicus| (Rat) Length = 400 Score = 65.5 bits (158), Expect = 5e-10 Identities = 56/211 (26%), Positives = 92/211 (43%), Gaps = 3/211 (1%) Frame = +1 Query: 124 GDFTLLSCGRPRRDKVDGKVVWITGASRGIGEVLSMQFASLGAKL---ILSARNKEELER 294 G L RP R V + V ITG G G+ + + ++G + +L LE Sbjct: 65 GWIALSRLARPPRLPVATRAVLITGCDTGFGKETAKKLDAMGFTVLATVLDLNGPGALE- 123 Query: 295 VKHNIMSKHPDSKVEVLPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGA 474 + ++++L MDL+ E + V+ ++ +S G+ +++NA Sbjct: 124 -----LRARCSPRLKLLQMDLTKPE-DISRVLEITKAHTASTGLWGLVNNAGLNMVVADV 177 Query: 475 LEETEEGLKATFKVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASK 654 + +VN FG + LT+ L P +L G V + S AG +P P A Y SK Sbjct: 178 ELSPVVTFRECMEVNFFGALELTKGLLP-LLRHSRGRIVTVGSPAGDMPYPCLAAYGTSK 236 Query: 655 HALNGYFASLRSELCTKGIKVTVVCPGPIET 747 A+ + EL GIKV+++ PG +T Sbjct: 237 AAIALLMDTFSCELLPWGIKVSIIQPGCFKT 267
>P80365:DHI2_HUMAN Corticosteroid 11-beta-dehydrogenase isozyme 2 - Homo sapiens| (Human) Length = 405 Score = 65.5 bits (158), Expect = 5e-10 Identities = 53/212 (25%), Positives = 93/212 (43%) Frame = +1 Query: 112 VTADGDFTLLSCGRPRRDKVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELE 291 + A G L RP+R V + V ITG G G+ + + S+G ++ + Sbjct: 61 LAAAGWIALSRLARPQRLPVATRAVLITGCDSGFGKETAKKLDSMGFTVLATVLELNSPG 120 Query: 292 RVKHNIMSKHPDSKVEVLPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRG 471 ++ ++ +L MDL+ + V+ ++ +S G+ +++NA Sbjct: 121 AIELRTCCS---PRLRLLQMDLTKPG-DISRVLEFTKAHTTSTGLWGLVNNAGHNEVVAD 176 Query: 472 ALEETEEGLKATFKVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSAS 651 A ++ +VN FG + LT+ L P +L G V + S AG +P P Y S Sbjct: 177 AELSPVATFRSCMEVNFFGALELTKGLLP-LLRSSRGRIVTVGSPAGDMPYPCLGAYGTS 235 Query: 652 KHALNGYFASLRSELCTKGIKVTVVCPGPIET 747 K A+ + EL G+KV+++ PG +T Sbjct: 236 KAAVALLMDTFSCELLPWGVKVSIIQPGCFKT 267
>O77667:DHI2_BOVIN Corticosteroid 11-beta-dehydrogenase isozyme 2 - Bos taurus| (Bovine) Length = 404 Score = 65.5 bits (158), Expect = 5e-10 Identities = 58/216 (26%), Positives = 99/216 (45%), Gaps = 4/216 (1%) Frame = +1 Query: 112 VTADGDFTLLSCGRPRRDKVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELE 291 + A G L RP+R V + V ITG G G + + ++G ++ + + Sbjct: 61 LAATGWIVLSRLARPQRLPVATRAVLITGCDSGFGNATAKKLDTMGFTVLATVLDLNSPG 120 Query: 292 RVKHNIMSKHPDSKVEVLPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRG 471 ++ S++++L MDL+ + V+ + S G+ +++NA + Sbjct: 121 ALELRACCS---SRLKLLQMDLTKPG-DISRVLEFTKVHTPSTGLWGLVNNAG----QNI 172 Query: 472 ALEETEEGLKATFK----VNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQAL 639 + + E ATF+ VN FG + +T+ L P +L R G V +SS AG +P P A Sbjct: 173 FVADAELCPVATFRTCMEVNFFGALEMTKGLLP-LLRRSSGRIVTVSSPAGDMPFPCLAA 231 Query: 640 YSASKHALNGYFASLRSELCTKGIKVTVVCPGPIET 747 Y SK AL + EL G+KV+++ P +T Sbjct: 232 YGTSKAALALLMGNFSCELLPWGVKVSIIQPACFKT 267
>O17795:DHBX_CAEEL Putative steroid dehydrogenase stdh-2 - Caenorhabditis elegans| Length = 315 Score = 65.5 bits (158), Expect = 5e-10 Identities = 52/200 (26%), Positives = 91/200 (45%), Gaps = 5/200 (2%) Frame = +1 Query: 190 ITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDE 369 +TGA+ GIG+ S + A G + + +R + +LE+ K +I+ K PD +V D ++ Sbjct: 52 VTGATDGIGKSYSFELARRGFNVYIVSRTQSKLEQTKKDILEKQPDIEVRFATYDFTNPS 111 Query: 370 KSLKEVVHSAESLFSSAGIDYMMHNAA--FERPKRGALEETEEGLKATFKVNVFGTITLT 543 + E + S + + +++N F+ P+ L + G+ + V + T+ T Sbjct: 112 VTDYEKLLSK---LNEVSVGILINNVGMFFDYPE--MLHKINGGIDSIANVIIINTLPAT 166 Query: 544 RLLA---PFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 714 L A P M+ R G V + S AG V ++YSA+K + LR E GI Sbjct: 167 LLSAGILPQMVSRKAGIIVNIGSFAGVVKLAEWSIYSATKKYVEWLTGCLRKEYSHHGII 226 Query: 715 VTVVCPGPIETPESSGATSS 774 + P + T + +S Sbjct: 227 FQAITPAMVATKMAGNPNTS 246
>Q17703:DHBV_CAEEL Putative steroid dehydrogenase stdh-1 - Caenorhabditis elegans| Length = 314 Score = 65.5 bits (158), Expect = 5e-10 Identities = 52/200 (26%), Positives = 89/200 (44%), Gaps = 5/200 (2%) Frame = +1 Query: 190 ITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDE 369 +TGA+ GIG+ S + A G + + +R + +LE K I+ HPD +V D ++ Sbjct: 52 VTGATDGIGKSYSFELAKRGFNVYIVSRTQSKLEHTKKEILEVHPDIEVRFATFDFTNPS 111 Query: 370 KSLKEVVHSAESLFSSAGIDYMMHNAA--FERPKRGALEETEEGLKATFKVNVFGTITLT 543 S E + S + I +++N F+ P+ L + G+ + V + T+ T Sbjct: 112 VSDYEKLLSK---LNEVSIGILINNVGMFFDYPE--MLHKINGGIDSIANVTIINTLPAT 166 Query: 544 RLLA---PFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 714 L A P M+ R G V + S AG ++YSA+K + L+ E +GI Sbjct: 167 LLSAGILPQMVPRKAGIIVNIGSVAGLATMAEWSVYSATKKYVEWITGCLQKEYGHQGII 226 Query: 715 VTVVCPGPIETPESSGATSS 774 + P + T + +S Sbjct: 227 FQAITPAMVATKMAGNPNTS 246
>O54939:DHB3_RAT Estradiol 17-beta-dehydrogenase 3 - Rattus norvegicus (Rat)| Length = 306 Score = 65.5 bits (158), Expect = 5e-10 Identities = 58/227 (25%), Positives = 101/227 (44%), Gaps = 1/227 (0%) Frame = +1 Query: 175 GKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMD 354 G+ ITGA GIG+ S + A G ++L +R E+L+ + I + S+V+V+ D Sbjct: 44 GQWAVITGAGDGIGKAYSFELARHGLNVVLISRTLEKLQVISEEI-ERTTGSRVKVVQAD 102 Query: 355 LSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAF-ERPKRGALEETEEGLKATFKVNVFGT 531 + ++ + E I +++N T ++ N+ Sbjct: 103 FTRED-----IYDHIEEQLKGLEIGVLVNNVGMLPNLLPSHFLSTSGESQSVIHCNITSV 157 Query: 532 ITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 711 + +T+L+ M R G + +SS G P P +LYSASK + + +L E KGI Sbjct: 158 VKMTQLVLKHMESRRRGLILNISSGVGVRPWPLYSLYSASKAFVCTFSKALNVEYRDKGI 217 Query: 712 KVTVVCPGPIETPESSGATSSSQRHSSEKRVSVERCAELTIVAATHG 852 + V+ P + TP + +S ++++ V E +TI A T G Sbjct: 218 IIQVLTPYSVSTPMTKYLNTSRVTKTADEFVK-ESLKYVTIGAETCG 263
>P51657:DHB1_RAT Estradiol 17-beta-dehydrogenase 1 - Rattus norvegicus (Rat)| Length = 344 Score = 65.5 bits (158), Expect = 5e-10 Identities = 60/198 (30%), Positives = 92/198 (46%), Gaps = 5/198 (2%) Frame = +1 Query: 169 VDGKVVWITGASRGIGEVLSMQFAS---LGAKLILSARN-KEELERVKHNIMSKHPDSKV 336 +D VV ITG S GIG L+++ AS K+ + R+ K + ++ P + Sbjct: 1 MDSTVVLITGCSSGIGLHLAVRLASDRSQSFKVYATLRDLKSQGPLLEAARAQGCPPGSL 60 Query: 337 EVLPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETE-EGLKATFK 513 E+L +D+ E V +A + + +D ++ NA R G LE E + A Sbjct: 61 EILELDVRDSES-----VAAARACVTEGRVDVLVCNAG--RGLFGPLEAHELNAVGAVLD 113 Query: 514 VNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSE 693 VNV GTI + + P M R G +V +S G + P +Y ASK AL G SL Sbjct: 114 VNVLGTIRMLQAFLPDMKRRHSGRVLVTASVGGLMGLPFHEVYCASKFALEGLCESLAIL 173 Query: 694 LCTKGIKVTVVCPGPIET 747 L G+ V+++ G + T Sbjct: 174 LPLFGVHVSLIECGAVHT 191
>P72220:BPHB_PSEPU Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase - Pseudomonas putida| Length = 277 Score = 65.5 bits (158), Expect = 5e-10 Identities = 58/199 (29%), Positives = 96/199 (48%), Gaps = 5/199 (2%) Frame = +1 Query: 166 KVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVL 345 K+ G+VV ITG + G+G L +F + AK+ + ++ E L +++ + H D+ + V Sbjct: 2 KLTGEVVLITGGASGLGRALVDRFVAERAKVAVLDKSAERLAQLE----TDHGDNVLGV- 56 Query: 346 PMDLSSDEKSLKEVVHSAESLFSSAG-IDYMMHNAAFERPKRGALEETEEGLKA----TF 510 + D +SL++ +A + G ID ++ NA ++ EE L A F Sbjct: 57 ----TGDVRSLEDQKQAASRCVAKFGKIDTLIPNAGIWDYSTALIDLPEESLDAAFDEVF 112 Query: 511 KVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRS 690 +NV G I + P ++ G+ + S AG P G LY+A+KHA+ G L Sbjct: 113 HINVKGYIHAVKACLPALV-ASRGNVIFTISNAGFYPNGGGPLYTAAKHAVVGLVRELAF 171 Query: 691 ELCTKGIKVTVVCPGPIET 747 EL ++V V PG I + Sbjct: 172 ELAPY-VRVNGVGPGGINS 189
>Q46381:BPHB_COMTE Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase - Comamonas| testosteroni (Pseudomonas testosteroni) Length = 281 Score = 65.5 bits (158), Expect = 5e-10 Identities = 61/213 (28%), Positives = 98/213 (46%), Gaps = 9/213 (4%) Frame = +1 Query: 166 KVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVL 345 K+ G+V ITG + G+G L +F + GA++ + ++ E L ++ H + V V+ Sbjct: 2 KLTGEVALITGGASGLGRALVDRFVAEGARVAVLDKSAERLRELE----VAHGGNAVGVV 57 Query: 346 PMDLSSDEKSLKEVVHSAESLFSSAG-IDYMMHNAAFERPKRGALEETEEGLKAT----F 510 D +SL++ +AE ++ G ID ++ NA + E+ + A F Sbjct: 58 -----GDVRSLQDQKRAAERCLAAFGKIDTLIPNAGIWDYSTALADLPEDKIDAAFDDIF 112 Query: 511 KVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRS 690 VNV G I + P ++ G V S AG P G LY+A+KHA+ G + Sbjct: 113 HVNVKGYIHAVKACLPALVS-SRGSVVFTISNAGFYPNGGGPLYTATKHAVVGLVRQMAF 171 Query: 691 ELCTKGIKVTVVCPGPIET----PESSGATSSS 777 EL ++V V PG + T P S G + S Sbjct: 172 ELAPH-VRVNGVAPGGMNTDLRGPSSLGLSEQS 203
>Q60V51:LE767_CAEBR Putative steroid dehydrogenase let-767 - Caenorhabditis briggsae| Length = 316 Score = 65.1 bits (157), Expect = 7e-10 Identities = 51/196 (26%), Positives = 89/196 (45%), Gaps = 7/196 (3%) Frame = +1 Query: 190 ITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLS--- 360 ITGA+ GIG+ + + A G + + +R + +L+ K I+ K+P+ +V D + Sbjct: 52 ITGATDGIGKAYAFELARRGFNVFIVSRTQSKLDETKKEILEKYPNIEVRTAAYDFTNAA 111 Query: 361 -SDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTIT 537 S K+L E ++ E I +++N L + + G++ + T+ Sbjct: 112 PSGYKNLLETLNKVE-------IGVLVNNVGLSYEYPDVLHKVDGGIERLANITTINTLP 164 Query: 538 LTRLLA---PFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKG 708 T L A P M+ R G V + S+A A+YSA+K ++ A LR E +G Sbjct: 165 PTLLSAGILPQMVARKAGVIVNVGSSASANQMALWAVYSATKKYVSWLTAILRKEYEHQG 224 Query: 709 IKVTVVCPGPIETPES 756 I + + P + T S Sbjct: 225 ITIQTIAPMMVATKMS 240
>Q10130:DHS5_CAEEL Putative oxidoreductase dhs-5 - Caenorhabditis elegans| Length = 378 Score = 65.1 bits (157), Expect = 7e-10 Identities = 49/200 (24%), Positives = 86/200 (43%), Gaps = 1/200 (0%) Frame = +1 Query: 151 RPRRDKVDGKVVWITGASRGIGEVLSMQFASLGA-KLILSARNKEELERVKHNIMSKHPD 327 +P ++ + ++G + GIG+ +++ A G K +L RN ++L+ VK I KH D Sbjct: 80 KPNLEQYQHRWTVVSGGTDGIGKAYTLELAKRGLRKFVLIGRNPKKLDSVKSEIEEKHSD 139 Query: 328 SKVEVLPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKAT 507 ++++ D S + S S S + +++++ R + + Sbjct: 140 AQIKTFVFDFGSGDFS------SLRDYISDIDVGFVVNSVGTGRDNLERYGDNPDEDTQI 193 Query: 508 FKVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLR 687 +VN G + P M G G VV+SS+ G P P A Y A+K + S+ Sbjct: 194 LRVNGMGAAEFLSCVLPPMEKSGGGQIVVLSSSQGVRPIPMLAAYCATKALMTFLCESID 253 Query: 688 SELCTKGIKVTVVCPGPIET 747 E T I V + P + T Sbjct: 254 REYST--INVQTLIPALVAT 271
>P51661:DHI2_MOUSE Corticosteroid 11-beta-dehydrogenase isozyme 2 - Mus musculus| (Mouse) Length = 386 Score = 65.1 bits (157), Expect = 7e-10 Identities = 57/212 (26%), Positives = 98/212 (46%), Gaps = 4/212 (1%) Frame = +1 Query: 124 GDFTLLSCGRPRRDKVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKH 303 G L RP R V + V ITG G G+ + + ++G ++ + + ++ Sbjct: 65 GWIALSRLARPPRLPVATRAVLITGCDTGFGKETAKKLDAMGFTVLATVLDLNSPGALEL 124 Query: 304 NIMSKHPDSKVEVLPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEE 483 + ++++L MDL+ E + V+ ++ +S G+ +++NA + + Sbjct: 125 RDLCS---PRLKLLQMDLTKAE-DISRVLEITKAHTASTGLWGLVNNAGLNI----VVAD 176 Query: 484 TEEGLKATFK----VNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSAS 651 E ATF+ VN FG + LT+ L P +L G V + S AG +P P A Y S Sbjct: 177 VELSPVATFRKCMEVNFFGALELTKGLLP-LLRHSRGRIVTVGSPAGDMPYPCLAAYGTS 235 Query: 652 KHALNGYFASLRSELCTKGIKVTVVCPGPIET 747 K A+ + EL GIKV+++ PG +T Sbjct: 236 KAAIALLMDTFGCELLPWGIKVSIIKPGCFKT 267
>P51656:DHB1_MOUSE Estradiol 17-beta-dehydrogenase 1 - Mus musculus (Mouse)| Length = 344 Score = 65.1 bits (157), Expect = 7e-10 Identities = 62/198 (31%), Positives = 95/198 (47%), Gaps = 5/198 (2%) Frame = +1 Query: 169 VDGKVVWITGASRGIGEVLSMQFAS---LGAKLILSARN-KEELERVKHNIMSKHPDSKV 336 +D VV ITG S GIG L+++ AS K+ + R+ K + ++ P + Sbjct: 1 MDPTVVLITGCSSGIGMHLAVRLASDRSQSFKVYATLRDLKAQGPLLEAARTQGCPPGSL 60 Query: 337 EVLPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETE-EGLKATFK 513 E+L +D+ D KS V +A++ + +D ++ NA R G LE E + A Sbjct: 61 EILELDVR-DSKS----VAAAQACVTEGRVDVLVCNAG--RGLFGPLEAHELNAVGAVLD 113 Query: 514 VNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSE 693 VNV GTI + + P M R G +V +S G + P +Y ASK AL G SL Sbjct: 114 VNVLGTIRMLQAFLPDMKRRHSGRVLVTASVGGLMGLPFHEVYCASKFALEGLCESLAIL 173 Query: 694 LCTKGIKVTVVCPGPIET 747 L G+ V+++ G + T Sbjct: 174 LPLFGVHVSLIECGAVHT 191
>P33368:YOHF_ECOLI Uncharacterized oxidoreductase yohF - Escherichia coli| Length = 253 Score = 64.7 bits (156), Expect = 9e-10 Identities = 57/215 (26%), Positives = 100/215 (46%), Gaps = 2/215 (0%) Frame = +1 Query: 178 KVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDL 357 +V IT + GIG+ ++ A G + ++ + EE + + H + E++ +DL Sbjct: 3 QVAIITASDSGIGKECALLLAQQGFDIGITWHSDEEGAKDTAREVVSH-GVRAEIVQLDL 61 Query: 358 SSDEKSLKEVVHSAESLFSSAG-IDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTI 534 + L E + E L G ID +++NA K L+ + + F V+V G Sbjct: 62 GN----LPEGALALEKLIQRLGRIDVLVNNAG-AMTKAPFLDMAFDEWRKIFTVDVDGAF 116 Query: 535 TLTRLLAPFMLDRGMGHFVV-MSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 711 +++ A M+ +G G ++ ++S P P + Y+A+KHAL G ++ EL I Sbjct: 117 LCSQIAARQMVKQGQGGRIINITSVHEHTPLPDASAYTAAKHALGGLTKAMALELVRHKI 176 Query: 712 KVTVVCPGPIETPESSGATSSSQRHSSEKRVSVER 816 V V PG I TP +G S + +E + + R Sbjct: 177 LVNAVAPGAIATP-MNGMDDSDVKPDAEPSIPLRR 210
>Q8CEE7:RDH13_MOUSE Retinol dehydrogenase 13 - Mus musculus (Mouse)| Length = 334 Score = 64.7 bits (156), Expect = 9e-10 Identities = 57/211 (27%), Positives = 93/211 (44%), Gaps = 13/211 (6%) Frame = +1 Query: 154 PRRDKVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSK 333 P + + GK V +TGA+ GIG+ +++ A G +IL+ R+ E+ E +I + + + Sbjct: 31 PSKATIPGKTVIVTGANTGIGKQTALELAKRGGNVILACRDMEKCEVAAKDIRGETLNPR 90 Query: 334 VEVLPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFK 513 V +DL+S KS++E + +D +++NAA R TE+G + F Sbjct: 91 VRAERLDLAS-LKSIREFARKV--IKEEERVDILVNNAAVMRCPHWT---TEDGFEMQFG 144 Query: 514 VNVFGTITLTRLLAPFMLDRGMGHFVVMSS---AAGKVPTPG----------QALYSASK 654 VN G LT LL + + +SS AG + +A Y SK Sbjct: 145 VNYLGHFLLTNLLLDKLKASAPSRIINLSSLAHVAGHIDFEDLNWQMKKYDTKAAYCQSK 204 Query: 655 HALNGYFASLRSELCTKGIKVTVVCPGPIET 747 A+ + L L G+ V + PG T Sbjct: 205 LAVVLFTKELSHRLQGSGVTVNALHPGVART 235
>P17611:NODG_AZOBR Nodulation protein G - Azospirillum brasilense| Length = 246 Score = 64.7 bits (156), Expect = 9e-10 Identities = 55/191 (28%), Positives = 88/191 (46%), Gaps = 1/191 (0%) Frame = +1 Query: 178 KVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHP-DSKVEVLPMD 354 K+ +TGA G+G + A G I++A E + + K V D Sbjct: 4 KIALVTGAMGGLGTAICQALAKDGC--IVAANCLPNFEPAAAWLGQQEALGFKFYVAEGD 61 Query: 355 LSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTI 534 +S D +S K +V E+ +D +++NA R K A + + A N+ Sbjct: 62 VS-DFESCKAMVAKIEA--DLGPVDILVNNAGITRDKFFAKMDKAQW-DAVIATNLSSLF 117 Query: 535 TLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 714 +T+ ++P M +RG G + +SS G GQ YSA+K + G+ +L +EL TKG+ Sbjct: 118 NVTQQVSPKMAERGWGRIINISSVNGVKGQAGQTNYSAAKAGVIGFTKALAAELATKGVT 177 Query: 715 VTVVCPGPIET 747 V + PG I T Sbjct: 178 VNAIAPGYIGT 188
>Q02207:FOX2_YEAST Peroxisomal hydratase-dehydrogenase-epimerase - Saccharomyces| cerevisiae (Baker's yeast) Length = 900 Score = 64.7 bits (156), Expect = 9e-10 Identities = 54/190 (28%), Positives = 95/190 (50%), Gaps = 5/190 (2%) Frame = +1 Query: 178 KVVWITGASRGIGEVLSMQFASLGAKLILSARNK-----EELERVKHNIMSKHPDSKVEV 342 KVV +TGA G+G+ ++ FA GAK++++ EE+ ++ + + PDS V Sbjct: 323 KVVVVTGAGGGLGKSHAIWFARYGAKVVVNDIKDPFSVVEEINKL-YGEGTAIPDSHDVV 381 Query: 343 LPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNV 522 L ++ +A S F +D +++NA R K L+ +E A KV++ Sbjct: 382 TEAPL---------IIQTAISKFQR--VDILVNNAGILRDK-SFLKMKDEEWFAVLKVHL 429 Query: 523 FGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCT 702 F T +L++ + P + G + +S +G GQA Y+A+K A+ G+ ++ E Sbjct: 430 FSTFSLSKAVWPIFTKQKSGFIINTTSTSGIYGNFGQANYAAAKAAILGFSKTIALEGAK 489 Query: 703 KGIKVTVVCP 732 +GI V V+ P Sbjct: 490 RGIIVNVIAP 499 Score = 60.5 bits (145), Expect = 2e-08 Identities = 55/190 (28%), Positives = 87/190 (45%), Gaps = 5/190 (2%) Frame = +1 Query: 178 KVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDL 357 +VV ITGA G+G+V ++ +AS GAK++++ L HN SK D V+ + Sbjct: 10 RVVVITGAGGGLGKVYALAYASRGAKVVVNDLGGT-LGGSGHN--SKAADLVVDEIKKAG 66 Query: 358 SSDEKSLKEVVHSAESLFSSA-----GIDYMMHNAAFERPKRGALEETEEGLKATFKVNV 522 + V + E + +A +D +++NA R A + TE + V++ Sbjct: 67 GIAVANYDSVNENGEKIIETAIKEFGRVDVLINNAGILRDVSFA-KMTEREFASVVDVHL 125 Query: 523 FGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCT 702 G L+R P+M + G + +S AG GQA YSA+K L G +L E Sbjct: 126 TGGYKLSRAAWPYMRSQKFGRIINTASPAGLFGNFGQANYSAAKMGLVGLAETLAKEGAK 185 Query: 703 KGIKVTVVCP 732 I V + P Sbjct: 186 YNINVNSIAP 195
>P39484:DHG3_BACME Glucose 1-dehydrogenase 3 - Bacillus megaterium| Length = 261 Score = 64.7 bits (156), Expect = 9e-10 Identities = 51/193 (26%), Positives = 92/193 (47%), Gaps = 2/193 (1%) Frame = +1 Query: 178 KVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDL 357 KVV ITG S G+G ++++F AK++++ N EE E + + + ++ D+ Sbjct: 8 KVVVITGGSTGLGRAMAVRFGQEEAKVVINYYNNEE-EALDAKKEVEEAGGQAIIVQGDV 66 Query: 358 SSDEKSLKEVVHSAESLFSSAG-IDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTI 534 + +E +VV+ ++ G +D M++NA E P E + + N+ G Sbjct: 67 TKEE----DVVNLVQTAIKEFGTLDVMINNAGVENPVPSH-ELSLDNWNKVIDTNLTGAF 121 Query: 535 TLTRLLAPFMLDRGM-GHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 711 +R + ++ + G+ + MSS +P P Y+ASK + +L E KGI Sbjct: 122 LGSREAIKYFVENDIKGNVINMSSVHEMIPWPLFVHYAASKGGMKQMTETLALEYAPKGI 181 Query: 712 KVTVVCPGPIETP 750 +V + PG + TP Sbjct: 182 RVNNIGPGAMNTP 194
>Q04520:BUDC_KLETE Acetoin(diacetyl) reductase - Klebsiella terrigena (Raoultella| terrigena) Length = 241 Score = 64.7 bits (156), Expect = 9e-10 Identities = 51/192 (26%), Positives = 87/192 (45%), Gaps = 1/192 (0%) Frame = +1 Query: 178 KVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDL 357 KV +TGA +GIG+ ++++ G + ++ N V I + + +D+ Sbjct: 3 KVALVTGAGQGIGKAIALRLVKDGFAVAIADYNDATATAVAAEI--NQAGGRAVAIKVDV 60 Query: 358 SSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTIT 537 S ++ V + ++L G + +++NA P TEE + + +NV G I Sbjct: 61 SRRDQVFAAVEQARKAL---GGFNVIVNNAGIA-PSTPIESITEEIVDRVYNINVKGVIW 116 Query: 538 -LTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 714 + + F + G V S AG V P A+YS+SK A+ G + +L GI Sbjct: 117 GMQAAVEAFKKEGHGGKIVNACSQAGHVGNPELAVYSSSKFAVRGLTQTAARDLAPLGIT 176 Query: 715 VTVVCPGPIETP 750 V CPG ++TP Sbjct: 177 VNGFCPGIVKTP 188
>Q8NBN7:RDH13_HUMAN Retinol dehydrogenase 13 - Homo sapiens (Human)| Length = 331 Score = 64.3 bits (155), Expect = 1e-09 Identities = 57/211 (27%), Positives = 94/211 (44%), Gaps = 13/211 (6%) Frame = +1 Query: 154 PRRDKVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSK 333 P + + GK V +TGA+ GIG+ +++ A G +IL+ R+ E+ E +I + + Sbjct: 31 PSKATIPGKTVIVTGANTGIGKQTALELARRGGNIILACRDMEKCEAAAKDIRGETLNHH 90 Query: 334 VEVLPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFK 513 V +DL+S KS++E +A+ + +D +++NA R TE+G + F Sbjct: 91 VNARHLDLAS-LKSIRE--FAAKIIEEEERVDILINNAGVMRCPHWT---TEDGFEMQFG 144 Query: 514 VNVFGTITLTRLLAPFMLDRGMGHFVVMSS---AAGKVPTPG----------QALYSASK 654 VN G LT LL + + +SS AG + +A Y SK Sbjct: 145 VNHLGHFLLTNLLLDKLKASAPSRIINLSSLAHVAGHIDFDDLNWQTRKYNTKAAYCQSK 204 Query: 655 HALNGYFASLRSELCTKGIKVTVVCPGPIET 747 A+ + L L G+ V + PG T Sbjct: 205 LAIVLFTKELSRRLQGSGVTVNALHPGVART 235
>O93868:MTDH_AGABI NADP-dependent mannitol dehydrogenase - Agaricus bisporus (Common| mushroom) Length = 262 Score = 64.3 bits (155), Expect = 1e-09 Identities = 54/213 (25%), Positives = 93/213 (43%), Gaps = 8/213 (3%) Frame = +1 Query: 178 KVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDL 357 K + +TG +RGIG + A+ GA + + R+ ++ V + K K + D+ Sbjct: 12 KTIIVTGGNRGIGLAFTRAVAAAGANVAVIYRSAKDAVEVTEKV-GKEFGVKTKAYQCDV 70 Query: 358 SSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTIT 537 S+ + K + L + +G+ + NA K A E T E K + VNVFG Sbjct: 71 SNTDIVTKTIQQIDADLGAISGL---IANAGVSVVKP-ATELTHEDFKFVYDVNVFGVFN 126 Query: 538 LTRLLAPFMLDRGM-GHFVVMSSAAGKVPTPG-------QALYSASKHALNGYFASLRSE 693 R +A L + G VV SS + ++ Q Y++SK A + L +E Sbjct: 127 TCRAVAKLWLQKQQKGSIVVTSSMSSQIINQSSLNGSLTQVFYNSSKAACSNLVKGLAAE 186 Query: 694 LCTKGIKVTVVCPGPIETPESSGATSSSQRHSS 792 + GI+V + PG + T +++ + H + Sbjct: 187 WASAGIRVNALSPGYVNTDQTAHMDKKIRDHQA 219
>Q9MA93:GRDH2_ARATH Glucose and ribitol dehydrogenase homolog 2 - Arabidopsis thaliana| (Mouse-ear cress) Length = 289 Score = 64.3 bits (155), Expect = 1e-09 Identities = 57/235 (24%), Positives = 103/235 (43%), Gaps = 6/235 (2%) Frame = +1 Query: 163 DKVDGKVVWITGASRGIGEVLSMQFASLGAKLILSA------RNKEELERVKHNIMSKHP 324 +K+ GKV +TG GIG+ + +A GA + + ++ EE R+ H + ++ Sbjct: 35 NKLHGKVALVTGGDSGIGKAVCHCYALEGASVAFTYVKGREDKDAEETLRLLHEVKTREA 94 Query: 325 DSKVEVLPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKA 504 + ++ DL +E + K VV E + +S G ++ N A E+ + + E L+ Sbjct: 95 KEPI-MIATDLGFEE-NCKRVV---EEVVNSFGRIDVLVNCAAEQHEVSIEDIDEARLER 149 Query: 505 TFKVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASL 684 F+ N+F L + M + + +S Y+A+K A+ + L Sbjct: 150 VFRTNIFSQFFLVKYALKHMKEGSS--IINTTSVVAYAGNSSLLEYTATKGAIVSFTRGL 207 Query: 685 RSELCTKGIKVTVVCPGPIETPESSGATSSSQRHSSEKRVSVERCAELTIVAATH 849 +L KGI+V V PGP+ TP + S ++R A+ VA ++ Sbjct: 208 ALQLAPKGIRVNGVAPGPVWTPLIPASFSEEAIKQFGSETPMKRAAQPVEVAPSY 262
>P37059:DHB2_HUMAN Estradiol 17-beta-dehydrogenase 2 - Homo sapiens (Human)| Length = 387 Score = 64.3 bits (155), Expect = 1e-09 Identities = 56/195 (28%), Positives = 86/195 (44%), Gaps = 6/195 (3%) Frame = +1 Query: 169 VDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNK-----EELERVKHNIMSKHPDSK 333 VD K V +TG G+G L LG + N+ EEL R + Sbjct: 80 VDQKAVLVTGGDCGLGHALCKYLDELGFTVFAGVLNENGPGAEELRRT--------CSPR 131 Query: 334 VEVLPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNA-AFERPKRGALEETEEGLKATF 510 + VL MD++ + +K+ ++ G+ +++NA P G L + K Sbjct: 132 LSVLQMDITKPVQ-IKDAYSKVAAMLQDRGLWAVINNAGVLGFPTDGELLLMTD-YKQCM 189 Query: 511 KVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRS 690 VN FGT+ +T+ P +L + G V +SS G P A Y +SK A+ + + +R Sbjct: 190 AVNFFGTVEVTKTFLP-LLRKSKGRLVNVSSMGGGAPMERLASYGSSKAAVTMFSSVMRL 248 Query: 691 ELCTKGIKVTVVCPG 735 EL GIKV + PG Sbjct: 249 ELSKWGIKVASIQPG 263
>P14061:DHB1_HUMAN Estradiol 17-beta-dehydrogenase 1 - Homo sapiens (Human)| Length = 328 Score = 64.3 bits (155), Expect = 1e-09 Identities = 59/194 (30%), Positives = 91/194 (46%), Gaps = 5/194 (2%) Frame = +1 Query: 181 VVWITGASRGIGEVLSMQFAS---LGAKLILSARNKEELERVKHNIMSKH-PDSKVEVLP 348 VV ITG S GIG L+++ AS K+ + R+ + R+ + P +E L Sbjct: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64 Query: 349 MDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEET-EEGLKATFKVNVF 525 +D+ D KS V +A + +D ++ NA G LE E+ + + VNV Sbjct: 65 LDVR-DSKS----VAAARERVTEGRVDVLVCNAGLGL--LGPLEALGEDAVASVLDVNVV 117 Query: 526 GTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTK 705 GT+ + + P M RG G +V S G + P +Y ASK AL G SL L Sbjct: 118 GTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPF 177 Query: 706 GIKVTVVCPGPIET 747 G+ ++++ GP+ T Sbjct: 178 GVHLSLIECGPVHT 191
>Q91XV4:DCXR_MESAU L-xylulose reductase - Mesocricetus auratus (Golden hamster)| Length = 244 Score = 64.3 bits (155), Expect = 1e-09 Identities = 62/223 (27%), Positives = 112/223 (50%), Gaps = 5/223 (2%) Frame = +1 Query: 175 GKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMD 354 G+ +TGA +GIG + + GA ++ +R + +L+ +++S+ P VE + +D Sbjct: 7 GRRALVTGAGKGIGRSTVLALQAAGAHVVAVSRTQADLD----SLVSECPG--VETVCVD 60 Query: 355 LSSDEKSLKEVVHSAESLFSSAG-IDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGT 531 L+ E + E SS G +D +++NAA + LE T+E +F VN+ Sbjct: 61 LADWE--------ATEQALSSVGPVDLLVNNAAVAL-LQPFLEVTKEAFDMSFNVNLRAV 111 Query: 532 ITLTRLLAPFMLDRGM-GHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKG 708 I +++++A M+ RG G V +SS A + ++Y ++K AL+ + EL Sbjct: 112 IQVSQIVARGMIARGAPGAIVNVSSQASQRALANHSVYCSTKGALDMLTKMMALELGPHK 171 Query: 709 IKVTVVCPGPIETPESSGATSSSQRHSSE---KRVSVERCAEL 828 I+V V P + T S G T+ S H ++ R+ + + AE+ Sbjct: 172 IRVNAVNPTVVMT--SMGRTNWSDPHKAKVMLDRIPLGKFAEV 212
>Q1JP75:DCXR_BOVIN L-xylulose reductase - Bos taurus (Bovine)| Length = 244 Score = 64.3 bits (155), Expect = 1e-09 Identities = 61/231 (26%), Positives = 115/231 (49%), Gaps = 4/231 (1%) Frame = +1 Query: 166 KVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVL 345 ++ G+ +TGA +GIG + + GA+++ +R + +L+ +++ + P VE + Sbjct: 4 RLAGRRALVTGAGKGIGRSIVKALHAAGARVVAVSRTQADLD----SLVRECPG--VETV 57 Query: 346 PMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNA--AFERPKRGALEETEEGLKATFKVN 519 +DL+ E + ++L +D +++NA AF +P LE T+E +F VN Sbjct: 58 CVDLADWEA-------TEQALGGVGPVDLLVNNAAVAFLQP---FLEVTKEAYDMSFSVN 107 Query: 520 VFGTITLTRLLAPFMLDRGM-GHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSEL 696 + I +++++A ++ RG G V +SS A + ++Y ++K AL+ + EL Sbjct: 108 LRAVIQVSQIVARGLIARGAPGVIVNVSSQASQRGLTNHSVYCSTKGALDTLTKVMAVEL 167 Query: 697 CTKGIKVTVVCPGPIETPESSGATSSSQRHSSE-KRVSVERCAELTIVAAT 846 I+V V P + TP A S Q+ + R+ + R AE+ V T Sbjct: 168 GPHKIRVNAVNPTVVMTPMGQAAWSDPQKAKAMLDRIPLGRFAEVENVVDT 218
>P35270:SPRE_HUMAN Sepiapterin reductase - Homo sapiens (Human)| Length = 261 Score = 63.9 bits (154), Expect = 1e-09 Identities = 64/215 (29%), Positives = 102/215 (47%), Gaps = 16/215 (7%) Frame = +1 Query: 181 VVWITGASRGIGEVLSMQFASL---GAKLILSARNKEELERVKHNIMSKHPDSKVEVLPM 351 V +TGASRG G L+ ASL G+ L+LSARN E L +++ + ++ +V +P Sbjct: 9 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPA 68 Query: 352 DLSSDEKSLKEVVHSAESLFSSAGID--YMMHNAAFERPKRGALEETEEG---LKATFKV 516 DL + E L++++ + L G+ +++NA G+L + +G L + +V Sbjct: 69 DLGA-EAGLQQLLGALRELPRPKGLQRLLLINNA-------GSLGDVSKGFVDLSDSTQV 120 Query: 517 NVFGTITLTRLLA-------PFMLDRGMGHFVV-MSSAAGKVPTPGQALYSASKHALNGY 672 N + + LT +L F G+ VV +SS P G ALY A K A + Sbjct: 121 NNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDML 180 Query: 673 FASLRSELCTKGIKVTVVCPGPIETPESSGATSSS 777 F L E ++V PGP++T A +S Sbjct: 181 FQVLALE--EPNVRVLNYAPGPLDTDMQQLARETS 213
>Q92781:RDH1_HUMAN 11-cis retinol dehydrogenase - Homo sapiens (Human)| Length = 318 Score = 63.9 bits (154), Expect = 1e-09 Identities = 51/192 (26%), Positives = 90/192 (46%), Gaps = 3/192 (1%) Frame = +1 Query: 184 VWITGASRGIGEVLSMQFASLGAKLI---LSARNKEELERVKHNIMSKHPDSKVEVLPMD 354 V+ITG G G +L++Q G +++ L+ E+L+RV S++ +D Sbjct: 31 VFITGCDSGFGRLLALQLDQRGFRVLASCLTPSGAEDLQRVA--------SSRLHTTLLD 82 Query: 355 LSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTI 534 ++ D +S+++ E AG+ +++NA T + + VN G I Sbjct: 83 IT-DPQSVQQAAKWVEMHVKEAGLFGLVNNAGVAGIIGPTPWLTRDDFQRVLNVNTMGPI 141 Query: 535 TLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 714 +T L P +L + G + ++S G++ G Y SK L + SLR ++ GI+ Sbjct: 142 GVTLALLP-LLQQARGRVINITSVLGRLAANGGG-YCVSKFGLEAFSDSLRRDVAHFGIR 199 Query: 715 VTVVCPGPIETP 750 V++V PG TP Sbjct: 200 VSIVEPGFFRTP 211
>P19992:HSD_STREX 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase - Streptomyces| exfoliatus (Streptomyces hydrogenans) Length = 255 Score = 63.9 bits (154), Expect = 1e-09 Identities = 56/196 (28%), Positives = 87/196 (44%), Gaps = 2/196 (1%) Frame = +1 Query: 169 VDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLP 348 + GK V ITG +RG+G + Q + GA+++L+ EE + Sbjct: 4 LSGKTVIITGGARGLGAEAARQAVAAGARVVLADVLDEEGAATAREL-----GDAARYQH 58 Query: 349 MDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETE--EGLKATFKVNV 522 +D++ +E + V ++ E S +D +++NA G ETE E + +N+ Sbjct: 59 LDVTIEEDWQRVVAYAREEFGS---VDGLVNNAGIST---GMFLETESVERFRKVVDINL 112 Query: 523 FGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCT 702 G + + P M D G G V +SSAAG + + Y ASK + G EL T Sbjct: 113 TGVFIGMKTVIPAMKDAGGGSIVNISSAAGLMGLALTSSYGASKWGVRGLSKLAAVELGT 172 Query: 703 KGIKVTVVCPGPIETP 750 I+V V PG TP Sbjct: 173 DRIRVNSVHPGMTYTP 188
>P10528:DHGA_BACME Glucose 1-dehydrogenase A - Bacillus megaterium| Length = 261 Score = 63.9 bits (154), Expect = 1e-09 Identities = 51/193 (26%), Positives = 92/193 (47%), Gaps = 2/193 (1%) Frame = +1 Query: 178 KVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDL 357 KVV ITG S G+G ++++F AK++++ N EE E + + + ++ D+ Sbjct: 8 KVVVITGGSTGLGRAMAVRFGQEEAKVVINYYNNEE-EALDAKKEVEEAGGQAIIVQGDV 66 Query: 358 SSDEKSLKEVVHSAESLFSSAG-IDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTI 534 + +E +VV+ ++ G +D M++NA E P E + + N+ G Sbjct: 67 TKEE----DVVNLVQTAIKEFGTLDVMINNAGVENPVPSH-ELSLDNWNKVIDTNLTGAF 121 Query: 535 TLTRLLAPFMLDRGM-GHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 711 +R + ++ + G+ + MSS +P P Y+ASK + +L E KGI Sbjct: 122 LGSREAIKYFVENDIKGNVINMSSVHEMIPWPLFVHYAASKGGMKLMTETLALEYAPKGI 181 Query: 712 KVTVVCPGPIETP 750 +V + PG + TP Sbjct: 182 RVNNIGPGAMNTP 194
>P39485:DHG4_BACME Glucose 1-dehydrogenase 4 - Bacillus megaterium| Length = 261 Score = 63.9 bits (154), Expect = 1e-09 Identities = 51/193 (26%), Positives = 92/193 (47%), Gaps = 2/193 (1%) Frame = +1 Query: 178 KVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDL 357 KVV ITG S G+G ++++F AK++++ N EE E + + + ++ D+ Sbjct: 8 KVVVITGGSTGLGRAMAVRFGQEEAKVVINYYNNEE-EALDAKKEVEEAGGQAIIVQGDV 66 Query: 358 SSDEKSLKEVVHSAESLFSSAG-IDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTI 534 + +E +VV+ ++ G +D M++NA E P E + + N+ G Sbjct: 67 TKEE----DVVNLVQTAIKEFGTLDVMINNAGVENPVPSH-ELSLDNWNKVIDTNLTGAF 121 Query: 535 TLTRLLAPFMLDRGM-GHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 711 +R + ++ + G+ + MSS +P P Y+ASK + +L E KGI Sbjct: 122 LGSREAIKYFVENDIKGNVINMSSVHEMIPWPLFVHYAASKGGMKLMTETLALEYAPKGI 181 Query: 712 KVTVVCPGPIETP 750 +V + PG + TP Sbjct: 182 RVNNIGPGAMNTP 194
>Q1WNP0:DHB1_PANTR Estradiol 17-beta-dehydrogenase 1 - Pan troglodytes (Chimpanzee)| Length = 328 Score = 63.9 bits (154), Expect = 1e-09 Identities = 59/194 (30%), Positives = 91/194 (46%), Gaps = 5/194 (2%) Frame = +1 Query: 181 VVWITGASRGIGEVLSMQFAS---LGAKLILSARNKEELERVKHNIMSKH-PDSKVEVLP 348 VV ITG S GIG L+++ AS K+ + R+ + R+ + P +E L Sbjct: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64 Query: 349 MDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEET-EEGLKATFKVNVF 525 +D+ D KS V +A + +D ++ NA G LE E+ + + VNV Sbjct: 65 LDVR-DSKS----VAAARERVTEGRVDVLVCNAGLGL--LGPLEALGEDAVASVLDVNVV 117 Query: 526 GTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTK 705 GT+ + + P M RG G +V S G + P +Y ASK AL G SL L Sbjct: 118 GTVRVLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPF 177 Query: 706 GIKVTVVCPGPIET 747 G+ ++++ GP+ T Sbjct: 178 GVHLSLIECGPVHT 191
>Q920N9:DCXR_CAVPO L-xylulose reductase - Cavia porcellus (Guinea pig)| Length = 244 Score = 63.9 bits (154), Expect = 1e-09 Identities = 63/229 (27%), Positives = 113/229 (49%), Gaps = 5/229 (2%) Frame = +1 Query: 175 GKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMD 354 G+ +TGA +GIG + + GA+++ +R +E+L+ +++ + P VE + +D Sbjct: 7 GRRALVTGAGKGIGRSTVLALKAAGAQVVAVSRTREDLD----DLVRECPG--VEPVCVD 60 Query: 355 LSSDEKSLKEVVHSAESLFSSAG-IDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGT 531 L+ E + E S+ G D +++NAA + LE T+E +F VN+ Sbjct: 61 LADWE--------ATEQALSNVGPADLLVNNAAVAL-LQPFLEVTKEACVTSFNVNLRAV 111 Query: 532 ITLTRLLAPFMLDRGM-GHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKG 708 I +++++A M+ RG+ G V +SS A + +Y ++K AL + EL Sbjct: 112 IQVSQIVAKGMIARGVPGAIVNVSSQASQRALTNHTVYCSTKGALYMLTKMMALELGPHK 171 Query: 709 IKVTVVCPGPIETPESSGATSSSQRHSSE---KRVSVERCAELTIVAAT 846 I+V V P + TP G T+ S H ++ R+ + + AE+ V T Sbjct: 172 IRVNAVNPTVVMTP--MGRTNWSDPHKAKAMLDRIPLGKFAEVENVVDT 218
>Q8KWT4:BACC2_BACSU Bacilysin biosynthesis oxidoreductase bacC - Bacillus subtilis| Length = 253 Score = 63.9 bits (154), Expect = 1e-09 Identities = 50/192 (26%), Positives = 88/192 (45%), Gaps = 1/192 (0%) Frame = +1 Query: 178 KVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDL 357 K V ITG + GIG F + A ++++ ++ + E + + K + ++ + D+ Sbjct: 6 KTVLITGGASGIGYAAVQAFLNQQANVVVADIDEAQGEAM----IRKENNDRLHFVHTDI 61 Query: 358 SSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETE-EGLKATFKVNVFGTI 534 + DE + + + SA F G+D +++NA E + E E VN+ G Sbjct: 62 T-DEPACQNAIRSAVDKFG--GLDVLINNAGIEIV--APIHEMELSNWNKVLNVNLTGMF 116 Query: 535 TLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 714 +++ +ML G G+ + S G V P Y+ASK + S+ + I+ Sbjct: 117 LMSKHALKYMLKSGKGNIINTCSVGGVVAWPDIPAYNASKGGVLQLTRSMAVDYAKHNIR 176 Query: 715 VTVVCPGPIETP 750 V VCPG I+TP Sbjct: 177 VNCVCPGIIDTP 188
>Q10216:YAY8_SCHPO Uncharacterized oxidoreductase C4H3.08 - Schizosaccharomyces pombe| (Fission yeast) Length = 286 Score = 63.5 bits (153), Expect = 2e-09 Identities = 55/230 (23%), Positives = 104/230 (45%), Gaps = 2/230 (0%) Frame = +1 Query: 166 KVDGKVVWITGASRGIGEVLSMQFASLGAKLILSA--RNKEELERVKHNIMSKHPDSKVE 339 K+ K +TG GIG+ ++ FA G+ L++S +++ E + I + + + Sbjct: 39 KLAEKKTLLTGGDSGIGKAAAVMFAREGSDLVISCLPEERDDAEVTRDLIEREGRNCWIW 98 Query: 340 VLPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVN 519 +D S + + L + +L ID +++N A+++ + + +E TFK N Sbjct: 99 EGKLDKSDNCRDLVDF-----ALKKLGWIDVLVNNIAYQQVAQSIEDIDDEQWDLTFKTN 153 Query: 520 VFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELC 699 +F +T+ M + V SS V P Y+++K A+ + L ++ Sbjct: 154 IFSFFWVTKAAISHM--KSGSSIVNCSSINAYVGRPDLLDYTSTKGAITAFTRGLSNQYA 211 Query: 700 TKGIKVTVVCPGPIETPESSGATSSSQRHSSEKRVSVERCAELTIVAATH 849 GI+V V PGPI TP S +T ++ +V + R + VA+ + Sbjct: 212 QHGIRVNAVAPGPIYTPLVS-STFPKEKIELSDQVPLGRMGQPVEVASCY 260
>Q45219:Y2146_BRAJA Probable short-chain type dehydrogenase/reductase blr2146 -| Bradyrhizobium japonicum Length = 281 Score = 63.5 bits (153), Expect = 2e-09 Identities = 55/197 (27%), Positives = 95/197 (48%), Gaps = 3/197 (1%) Frame = +1 Query: 166 KVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVL 345 + +GKV +TGA GIG+ ++ A G +++++ + I ++ + L Sbjct: 3 RFEGKVAVVTGAGAGIGKACALAIAREGGRVVVADIDGSAAIACTAQIAAEAGHALA--L 60 Query: 346 PMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFER--PKRGALEETEEGL-KATFKV 516 +D++ D +++ + +AE F G+D +++NA+ P+ A+ E E + T Sbjct: 61 AIDIA-DAQAVAALFETAERHFG--GVDLLVNNASAMHLTPRDRAILELELAVWDQTMAT 117 Query: 517 NVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSEL 696 N+ GT+ R P M+ RG G V MSS G Y+ASK A+N +SL ++ Sbjct: 118 NLRGTLLCCRQAIPRMIARGGGAIVNMSSCQGLSGDTALTSYAASKAAMNMLSSSLATQY 177 Query: 697 CTKGIKVTVVCPGPIET 747 I+ V PG I T Sbjct: 178 GHAQIRCNAVAPGLIMT 194
>P50202:MAS1_AGRT9 Agropine synthesis reductase - Agrobacterium tumefaciens (strain| 15955) Length = 430 Score = 63.5 bits (153), Expect = 2e-09 Identities = 47/197 (23%), Positives = 92/197 (46%) Frame = +1 Query: 169 VDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLP 348 + VV ++G +RGIG+ ++ G ++ L ARN ++L + ++ + L Sbjct: 197 IQSPVVMVSGVTRGIGKAIAEDLIRHGYRVSLGARNIQDLVAAFGDENEALHYARFDAL- 255 Query: 349 MDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFG 528 D S+K+ V + + F+ ID +++NA E E L+ + +N Sbjct: 256 -----DHSSMKDWVDTTIAKFNR--IDGLVNNAGCGDHVDLEKEINVELLQKQWDINCVA 308 Query: 529 TITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKG 708 + +T+L P++++ G G V ++S +G+ Y+ +KH L G + + G Sbjct: 309 PLIMTKLCMPYLIESGSGRIVNLNSMSGQRVANSLVGYNMTKHGLAGLTKTTQHVGWDHG 368 Query: 709 IKVTVVCPGPIETPESS 759 ++ +CPG + T SS Sbjct: 369 VRAVDICPGFVATNMSS 385
>Q59787:DHSO_RHOSH Sorbitol dehydrogenase - Rhodobacter sphaeroides (Rhodopseudomonas| sphaeroides) Length = 256 Score = 63.5 bits (153), Expect = 2e-09 Identities = 55/194 (28%), Positives = 91/194 (46%), Gaps = 1/194 (0%) Frame = +1 Query: 166 KVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVL 345 ++DGK ITG++RGIG + + GA++ ++ N LE + P + L Sbjct: 2 RLDGKTALITGSARGIGRAFAEAYVREGARVAIADIN---LEAARATAAEIGPAACAIAL 58 Query: 346 PMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVF 525 + +D+ S+ V AE L ID +++NAA +E T E F +NV Sbjct: 59 DV---TDQASIDRCV--AELLDRWGSIDILVNNAAL-FDLAPIVEITRESYDRLFAINVS 112 Query: 526 GTITLTRLLAPFMLDRGMGHFVV-MSSAAGKVPTPGQALYSASKHALNGYFASLRSELCT 702 GT+ + + +A M+ G G ++ M+S AG+ +Y A+K A+ S L Sbjct: 113 GTLFMMQAVARAMIAGGRGGKIINMASQAGRRGEALVGVYCATKAAVISLTQSAGLNLIR 172 Query: 703 KGIKVTVVCPGPIE 744 GI V + PG ++ Sbjct: 173 HGINVNAIAPGVVD 186
>Q920P0:DCXR_RAT L-xylulose reductase - Rattus norvegicus (Rat)| Length = 244 Score = 63.5 bits (153), Expect = 2e-09 Identities = 61/229 (26%), Positives = 113/229 (49%), Gaps = 5/229 (2%) Frame = +1 Query: 175 GKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMD 354 G+ +TGA +GIG + + GA+++ +R +E+L+ +++ + P VE + +D Sbjct: 7 GRRALVTGAGKGIGRSTVLALQAAGAQVVAVSRTREDLD----SLVRECPG--VEPVCVD 60 Query: 355 LSSDEKSLKEVVHSAESLFSSAG-IDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGT 531 L+ E + E S+ G +D +++NAA + LE T+E +F VN Sbjct: 61 LADWE--------ATEQALSNVGPVDLLVNNAAV-ATLQPFLEVTKEACDTSFNVNFRAV 111 Query: 532 ITLTRLLAPFMLDRGM-GHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKG 708 + +++++A M+ RG+ G V +SS A + +Y ++K AL+ + EL Sbjct: 112 VQVSQIVARGMIARGVPGAIVNVSSQASQRALTNHTVYCSTKGALDMLTKVMALELGPHK 171 Query: 709 IKVTVVCPGPIETPESSGATSSSQRHSSE---KRVSVERCAELTIVAAT 846 I+V V P + TP G + S H ++ R+ + + AE+ V T Sbjct: 172 IRVNAVNPTVVMTP--MGRANWSDPHKAKVMLDRIPLGKFAEVENVVDT 218
>P47227:BPHB_BURXL Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase - Burkholderia| xenovorans (strain LB400) Length = 277 Score = 63.5 bits (153), Expect = 2e-09 Identities = 60/213 (28%), Positives = 99/213 (46%), Gaps = 9/213 (4%) Frame = +1 Query: 166 KVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVL 345 K+ G+ V ITG + G+G L +F + GAK+ + ++ E L ++ + H D+ + ++ Sbjct: 2 KLKGEAVLITGGASGLGRALVDRFVAEGAKVAVLDKSAERLAELE----TDHGDNVLGIV 57 Query: 346 PMDLSSDEKSLKEVVHSAESLFSSAG-IDYMMHNAAFERPKRGALEETEEGLKA----TF 510 D +SL++ +A + G ID ++ NA ++ EE L A F Sbjct: 58 -----GDVRSLEDQKQAASRCVARFGKIDTLIPNAGIWDYSTALVDLPEESLDAAFDEVF 112 Query: 511 KVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRS 690 +NV G I + P ++ G+ + S AG P G LY+A+KHA+ G L Sbjct: 113 HINVKGYIHAVKACLPALV-ASRGNVIFTISNAGFYPNGGGPLYTAAKHAIVGLVRELAF 171 Query: 691 ELCTKGIKVTVVCPGPIET----PESSGATSSS 777 EL ++V V G I + P S G S + Sbjct: 172 ELAPY-VRVNGVGSGGINSDLRGPSSLGMGSKA 203
>P45200:Y1430_HAEIN Probable NADP-dependent dehydrogenase HI1430 - Haemophilus| influenzae Length = 252 Score = 63.2 bits (152), Expect = 3e-09 Identities = 57/251 (22%), Positives = 106/251 (42%), Gaps = 7/251 (2%) Frame = +1 Query: 190 ITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDE 369 +TGA+ G G + + G K+I + R + L + H LP L+ D Sbjct: 8 VTGATAGFGLAICKKLIEAGYKVIGTGRRADRLAEI-------HSQLGNNFLP--LAFDI 58 Query: 370 KSLKEVVHSAESLFSS-AGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTR 546 + + +++ +L +D +++NA A + + N+ G +T+TR Sbjct: 59 RDEQATINALNTLPEGWQAVDLLVNNAGLALGLEPAHKADLQDWYQMIDTNIKGLVTITR 118 Query: 547 LLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIKVTVV 726 L+ P M+ R G + +SS AG P G +Y +K + + +LR++L I+V+ V Sbjct: 119 LVLPNMVARNYGQIINLSSIAGTYPYAGSNVYGGTKAFVTQFSLNLRADLAGTKIRVSNV 178 Query: 727 CPGPIETPESSGA------TSSSQRHSSEKRVSVERCAELTIVAATHGLKEAWISYQPVL 888 PG E S +++ + + + V E A + + W+ QP Sbjct: 179 EPGLCGGTEFSNVRFHGDDERAAKVYENVQSVQPEDIANIVL----------WLHQQPEH 228 Query: 889 AVMYVVQYMPT 921 + ++ MPT Sbjct: 229 VNINRIEVMPT 239
>Q91WL8:WWOX_MOUSE WW domain-containing oxidoreductase - Mus musculus (Mouse)| Length = 414 Score = 63.2 bits (152), Expect = 3e-09 Identities = 55/183 (30%), Positives = 87/183 (47%), Gaps = 8/183 (4%) Frame = +1 Query: 175 GKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMD 354 GKVV +TGA+ GIG + FA GA +IL+ RN I+ + +KVE + +D Sbjct: 124 GKVVLVTGANSGIGFETAKSFALHGAHVILACRNLSRASEAVSRILEEWHKAKVEAMTLD 183 Query: 355 LSSDEKSLKEVVHSAESL-FSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGT 531 L+ L+ V H AE+ + + ++ NA G T++GL+ TF+VN G Sbjct: 184 LA----VLRSVQHFAEAFKAKNVSLHVLVCNAGTFALPWGL---TKDGLETTFQVNHLGH 236 Query: 532 ITLTRLLAPFMLDRGMGHFVVMSSAAGKV----PTPGQALYSASKHALNGYFASL---RS 690 L +LL + +V+SS + + + G+ S + Y+A L RS Sbjct: 237 FYLVQLLQDVLCRSSPARVIVVSSESHRFTDINDSSGKLDLSRLSPPRSDYWAMLAYNRS 296 Query: 691 ELC 699 +LC Sbjct: 297 KLC 299
>Q09517:LE767_CAEEL Putative steroid dehydrogenase let-767 - Caenorhabditis elegans| Length = 316 Score = 63.2 bits (152), Expect = 3e-09 Identities = 49/193 (25%), Positives = 89/193 (46%), Gaps = 4/193 (2%) Frame = +1 Query: 190 ITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDE 369 +TGA+ GIG+ + + A G ++L +R + +L+ K I+ K+ +V D ++ Sbjct: 52 VTGATDGIGKAYAFELARRGFNVLLVSRTQSKLDETKKEILEKYSSIEVRTAAFDFTNAA 111 Query: 370 KS-LKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTR 546 S K+++ + + I +++N L + + G++ + T+ T Sbjct: 112 PSAYKDLL----ATLNQVEIGVLINNVGMSYEYPDVLHKVDGGIERLANITTINTLPPTL 167 Query: 547 LLA---PFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIKV 717 L A P M+ R G V + S+AG A+YSA+K ++ A LR E +GI V Sbjct: 168 LSAGILPQMVARKAGVIVNVGSSAGANQMALWAVYSATKKYVSWLTAILRKEYEHQGITV 227 Query: 718 TVVCPGPIETPES 756 + P + T S Sbjct: 228 QTIAPMMVATKMS 240
>Q00791:STCU_EMENI Versicolorin reductase - Emericella nidulans (Aspergillus nidulans)| Length = 264 Score = 62.8 bits (151), Expect = 3e-09 Identities = 56/200 (28%), Positives = 91/200 (45%), Gaps = 6/200 (3%) Frame = +1 Query: 166 KVDGKVVWITGASRGIGEVLSMQFASLGAKLILS-ARNKEELERVKHNIMSKHPDS-KVE 339 ++DGKV +TGA RGIG +++ GAK++++ A ++E E+V I S D+ ++ Sbjct: 8 RLDGKVALVTGAGRGIGAAIAVALGQRGAKVVVNYANSREAAEKVVDEIKSNGSDAISIQ 67 Query: 340 VLPMDLSSDEKSLKEVVHS---AESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATF 510 D + K + + V + + S+AGI H + T + F Sbjct: 68 ADVGDPDAVTKLMDQAVEHFGYLDIVSSNAGIVSFGH----------VKDVTPDEFDRVF 117 Query: 511 KVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVP-TPGQALYSASKHALNGYFASLR 687 +VN G + R + R G ++ SS V P A+YS SK A++ + L Sbjct: 118 RVNTRGQFFVAR--EAYRHLREGGRIILTSSNTASVKGVPRHAVYSGSKGAIDTFVRCLA 175 Query: 688 SELCTKGIKVTVVCPGPIET 747 + K I V V PG I+T Sbjct: 176 IDCGDKKITVNAVAPGAIKT 195
>P19337:BAIA2_EUBSP Bile acid 7-dehydroxylase 2 - Eubacterium sp. (strain VPI 12708)| Length = 249 Score = 62.8 bits (151), Expect = 3e-09 Identities = 53/198 (26%), Positives = 83/198 (41%) Frame = +1 Query: 169 VDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLP 348 V KV ITG +RGIG + F GAK+ + +EE++ + +P+ +V Sbjct: 4 VQDKVTIITGGTRGIGFAAAKIFIDNGAKVSIFGETQEEVDTALAQLKELYPEEEVLGFA 63 Query: 349 MDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFG 528 DL+S + + V A+ +D M++NA +EE K +NV G Sbjct: 64 PDLTSRDAVMAAVGQVAQKY---GRLDVMINNAGI-TSNNVFSRVSEEEFKHIMDINVTG 119 Query: 529 TITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKG 708 M D G + +S G + Y ASK ++ G L E+ K Sbjct: 120 VFNGAWCAYQCMKDAKKGVIINTASVTGIFGSLSGVGYPASKASVIGLTHGLGREIIRKN 179 Query: 709 IKVTVVCPGPIETPESSG 762 I+V V PG + T ++G Sbjct: 180 IRVVGVAPGVVNTDMTNG 197
>Q89AG9:FABG_BUCBP 3-oxoacyl-[acyl-carrier-protein] reductase - Buchnera aphidicola| subsp. Baizongia pistaciae Length = 245 Score = 62.4 bits (150), Expect = 4e-09 Identities = 49/215 (22%), Positives = 103/215 (47%), Gaps = 1/215 (0%) Frame = +1 Query: 166 KVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVL 345 K K+ ITGA+RG+G+ ++ + ++ ++ ++ I++K+ + + Sbjct: 2 KTTKKIAVITGANRGLGKGIAEELSNTNNITVIGTSTSQK----GCKIINKYLKNNGIGI 57 Query: 346 PMDLSSDEKSLKEVVHSAESLFSSAG-IDYMMHNAAFERPKRGALEETEEGLKATFKVNV 522 +D+++ E+ + + ++ + G +D +++NA R K +T++ + VN+ Sbjct: 58 KLDITNPN----EITKTMDFVYKNFGRVDILINNAGIIRDKLLINMKTQDW-NSVLNVNL 112 Query: 523 FGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCT 702 +++ + M+ G + + S + GQ YSA+K L G+ SL EL Sbjct: 113 NSIFYMSKSVIRNMIKNKQGKIITIGSVIAHIGNCGQTNYSAAKLGLVGFHKSLALELAP 172 Query: 703 KGIKVTVVCPGPIETPESSGATSSSQRHSSEKRVS 807 KGI V ++ PG I+T G T++ + K +S Sbjct: 173 KGITVNMIAPGLIKT----GMTNNLSQKQLSKYLS 203
>Q62904:DHB7_RAT 3-keto-steroid reductase - Rattus norvegicus (Rat)| Length = 334 Score = 62.4 bits (150), Expect = 4e-09 Identities = 62/230 (26%), Positives = 98/230 (42%), Gaps = 40/230 (17%) Frame = +1 Query: 178 KVVWITGASRGIGEVLSMQFASLG--AKLILSARNKEELERVKHNIMSKHPDSKVEVLPM 351 KVV ITGAS GIG L + + L L+ RN + V+ +++ HP ++V ++ M Sbjct: 3 KVVLITGASSGIGLALCGRLLAEDDDLHLCLACRNLSKAGAVRDALLASHPSAEVSIVQM 62 Query: 352 DLSSDEKSLKEVVHSAESLFSS-AGIDYMMHNAA----------------FER------- 459 D+S +L+ VV AE + +DY+ NA F R Sbjct: 63 DVS----NLQSVVRGAEEVKRRFQRLDYLYLNAGIMPNPQLNLKAFFCGIFSRNVIHMFS 118 Query: 460 PKRGALEE----TEEGLKATFKVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPT- 624 G L + T +G + F+ N+FG L R L P + ++ +S+ + Sbjct: 119 TAEGLLTQNDKITADGFQEVFETNLFGHFILIRELEPLLCHSDNPSQLIWTSSRNAKKSN 178 Query: 625 ---------PGQALYSASKHALNGYFASLRSELCTKGIKVTVVCPGPIET 747 GQ YS+SK+A + +L KG+ +V CPG + T Sbjct: 179 FSLEDIQHAKGQEPYSSSKYATDLLNVALNRNFNQKGLYSSVTCPGVVMT 228
>O86034:BDHA_RHIME D-beta-hydroxybutyrate dehydrogenase - Rhizobium meliloti| (Sinorhizobium meliloti) Length = 258 Score = 62.4 bits (150), Expect = 4e-09 Identities = 47/192 (24%), Positives = 88/192 (45%), Gaps = 1/192 (0%) Frame = +1 Query: 178 KVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDL 357 K ITG++ GIG ++ A GA ++L+ + R + ++ V P D+ Sbjct: 3 KTAVITGSTSGIGLAIARTLAKAGANIVLNGFGAPDEIRTVTDEVAGLSSGTVLHHPADM 62 Query: 358 SSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETE-EGLKATFKVNVFGTI 534 + + + A+ G D +++NA + ++ +E+ E VN+ + Sbjct: 63 TKPSEIADMMAMVADRF---GGADILVNNAGVQFVEK--IEDFPVEQWDRIIAVNLSSSF 117 Query: 535 TLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 714 R P M +G G + ++SA G V +P ++ Y A+KH + G ++ E+ G+ Sbjct: 118 HTIRGAIPPMKKKGWGRIINIASAHGLVASPFKSAYVAAKHGIMGLTKTVALEVAESGVT 177 Query: 715 VTVVCPGPIETP 750 V +CPG + TP Sbjct: 178 VNSICPGYVLTP 189
>Q56632:VIBA_VIBCH Vibriobactin-specific 2,3-dihydro-2,3-dihydroxybenzoate| dehydrogenase - Vibrio cholerae Length = 262 Score = 62.0 bits (149), Expect = 6e-09 Identities = 52/193 (26%), Positives = 90/193 (46%) Frame = +1 Query: 169 VDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLP 348 V+ KV+ + G++RGIG + GA+++ + + L +++ ++PD ++ + Sbjct: 7 VNSKVL-LVGSARGIGFSVLEHLLQAGAQVMAADCEWQLLLEQSESLLGRYPD-QLTLKK 64 Query: 349 MDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFG 528 +DL+ E ++V AE + AG D+++ A E E + + F VN FG Sbjct: 65 LDLAEPEAVREQVNQWAEQV---AGFDHLVCCAGILHVAP-LHEMPMEQVSSIFTVNAFG 120 Query: 529 TITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKG 708 + + +A M R G V++ S A P Y ASK AL+ + EL G Sbjct: 121 VLACMQGVASSMKARQQGSMVIIGSNAANTPRMSIGAYGASKAALHMLVKCIGMELAPYG 180 Query: 709 IKVTVVCPGPIET 747 I+ +V PG T Sbjct: 181 IRCNLVSPGSTRT 193
>P39640:BACC_BACSU Bacilysin biosynthesis oxidoreductase bacC - Bacillus subtilis| Length = 253 Score = 61.6 bits (148), Expect = 7e-09 Identities = 51/192 (26%), Positives = 87/192 (45%), Gaps = 1/192 (0%) Frame = +1 Query: 178 KVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDL 357 K V ITG + GIG F A ++++ ++ + E + + K + ++ + D+ Sbjct: 6 KTVLITGGASGIGYAAVQAFLGQQANVVVADIDEAQGEAM----VRKENNDRLHFVQTDI 61 Query: 358 SSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETE-EGLKATFKVNVFGTI 534 + DE + + V SA F G+D +++NA E + E E +VN+ G Sbjct: 62 T-DEAACQHAVESAVHTFG--GLDVLINNAGIEIV--APIHEMELSDWNKVLQVNLTGMF 116 Query: 535 TLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 714 +++ ML G G+ + S G V P Y+ASK + S+ + I+ Sbjct: 117 LMSKHALKHMLAAGKGNIINTCSVGGLVAWPDIPAYNASKGGVLQLTKSMAVDYAKHQIR 176 Query: 715 VTVVCPGPIETP 750 V VCPG I+TP Sbjct: 177 VNCVCPGIIDTP 188
>Q12634:T4HR_MAGGR Tetrahydroxynaphthalene reductase - Magnaporthe grisea (Rice blast| fungus) (Pyricularia grisea) Length = 283 Score = 61.2 bits (147), Expect = 1e-08 Identities = 57/205 (27%), Positives = 94/205 (45%), Gaps = 7/205 (3%) Frame = +1 Query: 154 PRRDKVDGKVVWITGASRGIGEVLSMQFASLGAKLILS-ARNKEELERVKHNIMSKHPD- 327 P+ ++GKV +TGA RGIG ++M+ G K+I++ A + E E V I D Sbjct: 22 PQSASLEGKVALVTGAGRGIGREMAMELGRRGCKVIVNYANSTESAEEVVAAIKKNGSDA 81 Query: 328 ----SKVEVLPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEG 495 + V V+ + E+++K + + + S++G+ H + T E Sbjct: 82 ACVKANVGVVEDIVRMFEEAVK-IFGKLDIVCSNSGVVSFGH----------VKDVTPEE 130 Query: 496 LKATFKVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKV-PTPGQALYSASKHALNGY 672 F +N G + R A L+ G G ++M S G+ P A+YS SK A+ + Sbjct: 131 FDRVFTINTRGQFFVAR-EAYKHLEIG-GRLILMGSITGQAKAVPKHAVYSGSKGAIETF 188 Query: 673 FASLRSELCTKGIKVTVVCPGPIET 747 + ++ K I V VV PG I+T Sbjct: 189 ARCMAIDMADKKITVNVVAPGGIKT 213
>P55006:RDH7_RAT Retinol dehydrogenase 7 - Rattus norvegicus (Rat)| Length = 317 Score = 61.2 bits (147), Expect = 1e-08 Identities = 52/210 (24%), Positives = 100/210 (47%), Gaps = 2/210 (0%) Frame = +1 Query: 124 GDFTLLSCGRPRR--DKVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERV 297 G + LL R R+ + K V+ITG G G +L+ Q G +++ + ++ E++ Sbjct: 10 GLWNLLRLFRERKVVSHLQDKYVFITGCDSGFGNLLARQLDRRGMRVLAACLTEKGAEQL 69 Query: 298 KHNIMSKHPDSKVEVLPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGAL 477 + SK D ++E + +D++ E S+ + + G+ +++NA P Sbjct: 70 R----SKTSD-RLETVILDVTKTE-SIVAATQWVKERVGNRGLWGLVNNAGISVPMGPNE 123 Query: 478 EETEEGLKATFKVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKH 657 ++ + VN+ G I +T + P ++ + G V ++S G++ G Y SK+ Sbjct: 124 WMRKKDFASVLDVNLLGVIEVTLNMLP-LVRKARGRVVNIASTMGRMSLLGGG-YCISKY 181 Query: 658 ALNGYFASLRSELCTKGIKVTVVCPGPIET 747 + + SLR EL G+KV ++ PG +T Sbjct: 182 GVEAFSDSLRRELTYFGVKVAIIEPGGFKT 211
>P50169:RDH3_RAT Retinol dehydrogenase 3 - Rattus norvegicus (Rat)| Length = 317 Score = 61.2 bits (147), Expect = 1e-08 Identities = 52/210 (24%), Positives = 100/210 (47%), Gaps = 2/210 (0%) Frame = +1 Query: 124 GDFTLLSCGRPRR--DKVDGKVVWITGASRGIGEVLSMQFASLGAKLILSARNKEELERV 297 G + LL R R+ + K V+ITG G G +L+ Q G +++ + ++ E++ Sbjct: 10 GLWNLLRLFRERKVVSHLQDKYVFITGCDSGFGNLLARQLDRRGMRVLAACLTEKGAEQL 69 Query: 298 KHNIMSKHPDSKVEVLPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGAL 477 + SK D ++E + +D++ E S+ + + G+ +++NA P Sbjct: 70 R----SKTSD-RLETVILDVTKTE-SIVAATQWVKERVGNRGLWGLVNNAGISVPVGPNE 123 Query: 478 EETEEGLKATFKVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKH 657 ++ + VN+ G I +T + P ++ + G V ++S G++ G Y SK+ Sbjct: 124 WMRKKDFASVLDVNLLGVIEVTLNMLP-LVRKARGRVVNIASTMGRMSLVGGG-YCISKY 181 Query: 658 ALNGYFASLRSELCTKGIKVTVVCPGPIET 747 + + SLR EL G+KV ++ PG +T Sbjct: 182 GVEAFSDSLRRELTYFGVKVAIIEPGGFKT 211
>P14697:PHBB_RALEH Acetoacetyl-CoA reductase - Ralstonia eutropha (strain ATCC 17699 /| H16 / DSM 428 / Stanier 337) (Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)) Length = 246 Score = 61.2 bits (147), Expect = 1e-08 Identities = 53/196 (27%), Positives = 87/196 (44%), Gaps = 6/196 (3%) Frame = +1 Query: 178 KVVWITGASRGIGEVLSMQFASLGAKLIL-----SARNKEELERVKHNIMSKHPDSKVEV 342 ++ ++TG GIG + + A G +++ S R ++ LE+ K + S+ V Sbjct: 4 RIAYVTGGMGGIGTAICQRLAKDGFRVVAGCGPNSPRREKWLEQQKA-LGFDFIASEGNV 62 Query: 343 LPMDLSSDE-KSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVN 519 D + +K V + L ++AGI + F + R + A N Sbjct: 63 ADWDSTKTAFDKVKSEVGEVDVLINNAGIT---RDVVFRKMTRADWD-------AVIDTN 112 Query: 520 VFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELC 699 + +T+ + M DRG G V +SS G+ GQ YS +K L+G+ +L E+ Sbjct: 113 LTSLFNVTKQVIDGMADRGWGRIVNISSVNGQKGQFGQTNYSTAKAGLHGFTMALAQEVA 172 Query: 700 TKGIKVTVVCPGPIET 747 TKG+ V V PG I T Sbjct: 173 TKGVTVNTVSPGYIAT 188
>Q02338:BDH_HUMAN D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor -| Homo sapiens (Human) Length = 343 Score = 61.2 bits (147), Expect = 1e-08 Identities = 56/208 (26%), Positives = 89/208 (42%), Gaps = 17/208 (8%) Frame = +1 Query: 163 DKVDGKVVWITGASRGIGEVLSMQFASLGAKLI---------------LSARNKEELERV 297 + V K V +TG G G L+ S G + L + N + L V Sbjct: 51 EPVGSKAVLVTGCDSGFGFSLAKHLHSKGFLVFAGCLMKDKGHDGVKELDSLNSDRLRTV 110 Query: 298 KHNIMSKHPDSK-VEVLPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGA 474 + N+ S K VE++ L EK + L ++AGI G Sbjct: 111 QLNVCSSEEVEKVVEIVRSSLKDPEKGM-------WGLVNNAGISTF-----------GE 152 Query: 475 LEETE-EGLKATFKVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSAS 651 +E T E K +VN++GT+ +T+ P ++ R G V +SS G++ P ++ Y + Sbjct: 153 VEFTSLETYKQVAEVNLWGTVRMTKSFLP-LIRRAKGRVVNISSMLGRMANPARSPYCIT 211 Query: 652 KHALNGYFASLRSELCTKGIKVTVVCPG 735 K + + LR E+ G+KV+VV PG Sbjct: 212 KFGVEAFSDCLRYEMYPLGVKVSVVEPG 239 Database: uniprot_sprot.fasta.out Posted date: Jul 19, 2007 5:58 PM Number of letters in database: 100,686,439 Number of sequences in database: 274,295 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 274295 Number of Hits to DB: 233,312,597 Number of extensions: 4902940 Number of successful extensions: 14393 Number of sequences better than 10.0: 469 Number of HSP's gapped: 14052 Number of HSP's successfully gapped: 474 Length of query: 457 Length of database: 100,686,439 Length adjustment: 117 Effective length of query: 340 Effective length of database: 68,593,924 Effective search space: 23321934160 Effective search space used: 23321934160 Neighboring words threshold: 12 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
