ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | FLbaf88e23 |
|---|---|
| Clone Library Name | barley_pub |
>O23066:C86A2_ARATH Cytochrome P450 86A2 - Arabidopsis thaliana (Mouse-ear cress)| Length = 553 Score = 329 bits (843), Expect = 3e-89 Identities = 192/509 (37%), Positives = 263/509 (51%), Gaps = 17/509 (3%) Frame = +3 Query: 90 LVCCFLSYYRRLQSKKTTKEEPTEWPLLGHLLSTLANVSNLHDWATGVLATTRYNF---- 257 LV +Y+ Q + P WP+LG L + +HDW T L + Sbjct: 9 LVAVVAAYWLWFQRISRWLKGPRVWPVLGSLPGLIEQRDRMHDWITENLRACGGTYQTCI 68 Query: 258 ------AAHMGLTGVRFFLTCDPSNVRHIFISNSINYPRGEEYADIF-DVLGDGIFNADG 416 A GL V TCDP N+ H+ + NYP+G + +F D LG GIFN+DG Sbjct: 69 CAVPFLAKKQGLVTV----TCDPKNIEHMLKTRFDNYPKGPTWQAVFHDFLGQGIFNSDG 124 Query: 417 ESWRRQRAKSQLIMASPRFRSFSARCTRDKVERSLLPFLAHAADVGARCDLHDVLLRLMF 596 ++W QR + L + R R ++ P L A + DL D++LRL F Sbjct: 125 DTWLFQRKTAALEFTTRTLRQAMGRWVNRGIKLRFCPILETAQNNYEPVDLQDLILRLTF 184 Query: 597 DMTCNLVFGVDPGCLQIGLPSLPLARAMDDVLETLFLRHVIPPACWRLMYRYGFGPEKKM 776 D C L FG D GLP A A D E R ++P WRL G G E + Sbjct: 185 DNICGLAFGKDTRTCAPGLPENGFASAFDRATEASLQRFILPEFLWRLKKWLGLGLEVSL 244 Query: 777 AVARRIIDRFAADTIVKRRYSGHKLRGEGITESSDILSFFICNDDASEHSDEFLRDTAVN 956 + + ID + I R+ R G+ D+LS F+ D S +S+ FLR A+N Sbjct: 245 SRSLGEIDGYLDAVINTRKQELLSQRESGVQRHDDLLSRFMKKKDQS-YSETFLRHVALN 303 Query: 957 LLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVV-----LDASELS 1121 + AGRDT+ LSWFF+L+ +P VE I+ E+ + + D+ L+ E+ Sbjct: 304 FILAGRDTSSVALSWFFWLITTHPTVEDKIVREICSVLIETRGTDVSSWTAEPLEFDEVD 363 Query: 1122 SMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGK 1301 +VYL AAL E LRLYPSVP K ++D+LP G + AG + Y+ GRM+ WG+ Sbjct: 364 RLVYLKAALSETLRLYPSVPEDSKHVVNDDILPDGTFVPAGSSVTYSIYAAGRMKSTWGE 423 Query: 1302 DCMEFSPERWIT-DDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLE 1478 DC+EF PERWI+ DDGK + Y+F+AFNAGPR CLGK++A+ QMKT+AA VL L Sbjct: 424 DCLEFKPERWISPDDGKFVNHDQYRFVAFNAGPRICLGKDLAYLQMKTIAAAVLLRHRLT 483 Query: 1479 TVPGHTVKPKLSIVLHMKNGLAVTVKRRN 1565 PGH V+ K+S+ L MKNGL V V +R+ Sbjct: 484 VAPGHKVEQKMSLTLFMKNGLLVNVHKRD 512
>P48422:C86A1_ARATH Cytochrome P450 86A1 - Arabidopsis thaliana (Mouse-ear cress)| Length = 513 Score = 314 bits (805), Expect = 7e-85 Identities = 185/486 (38%), Positives = 256/486 (52%), Gaps = 16/486 (3%) Frame = +3 Query: 153 PTEWPLLGHLLSTLANVSNLHDW------ATGVLATTRYNFAAHMGLTGVRFFLTCDPSN 314 P P +G L +AN S +HDW ATG T + + +TC P N Sbjct: 33 PKVLPFVGSLPYLIANRSRIHDWIADNLRATGGTYQTCTMVIPFVAKAQGFYTVTCHPKN 92 Query: 315 VRHIFISNSINYPRGEEYADIF-DVLGDGIFNADGESWRRQRAKSQLIMASPRFRSFSAR 491 V HI + NYP+G + F D+LG GIFN+DG++W QR + L + R AR Sbjct: 93 VEHILKTRFDNYPKGPMWRAAFHDLLGQGIFNSDGDTWLMQRKTAALEFTTRTLRQAMAR 152 Query: 492 CTRDKVERSLLPFLAHAADVGARCDLHDVLLRLMFDMTCNLVFGVDPGCLQIGLPSLPLA 671 ++ L L A DL D+ LRL FD C L FG DP L + LP P + Sbjct: 153 WVNGTIKNRLWLILDRAVQNNKPVDLQDLFLRLTFDNICGLTFGKDPETLSLDLPDNPFS 212 Query: 672 RAMDDVLETLFLRHVIPPACWRLMYRYGFGPEKKMAVARRIIDRFAADTIVKRRYSGHKL 851 A D E R + WR+ G G E K+ + +++ + D I R+ S Sbjct: 213 VAFDTATEATLKRLLYTGFLWRIQKAMGIGSEDKLKKSLEVVETYMNDAIDARKNS---- 268 Query: 852 RGEGITESSDILSFFICNDDASEH--SDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCEN 1025 S D+LS F+ D + + + L+ A+N + AGRDT+ LSWFF+L+ N Sbjct: 269 ------PSDDLLSRFLKKRDVNGNVLPTDVLQRIALNFVLAGRDTSSVALSWFFWLVMNN 322 Query: 1026 PRVEQMILDELAPIAARKKVDDM-----VVLDASELSSMVYLHAALCECLRLYPSVPITH 1190 VE I++EL+ + + +D L+ E +VYL AAL E LRLYPSVP Sbjct: 323 REVETKIVNELSMVLKETRGNDQEKWTEEPLEFDEADRLVYLKAALAETLRLYPSVPQDF 382 Query: 1191 KAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPP- 1367 K +DVLP G + G + YS+GRM+ +WG+DC+EF PERW+T DG+ P Sbjct: 383 KYVVDDDVLPDGTFVPRGSTVTYSIYSIGRMKTIWGEDCLEFRPERWLTADGERFETPKD 442 Query: 1368 -YKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLETVPGHTVKPKLSIVLHMKNGLA 1544 YKF+AFNAGPRTCLGK++A+ QMK+VA+ VL + + VPGH V+ K+S+ L MKNGL Sbjct: 443 GYKFVAFNAGPRTCLGKDLAYNQMKSVASAVLLRYRVFPVPGHRVEQKMSLTLFMKNGLR 502 Query: 1545 VTVKRR 1562 V ++ R Sbjct: 503 VYLQPR 508
>P98188:C94A2_VICSA Cytochrome P450 94A2 - Vicia sativa (Spring vetch) (Tare)| Length = 513 Score = 280 bits (715), Expect = 2e-74 Identities = 182/508 (35%), Positives = 261/508 (51%), Gaps = 11/508 (2%) Frame = +3 Query: 75 YWFVGLVCCFLSYYRRLQSKKTTKEEPTEWPLLGHLLSTLANVSNLHDWATGVLATTRYN 254 +WF+ L S + S T P +P+ G S LAN W + +L T + Sbjct: 17 FWFLFLATKTKSKPPKTPSSTTNTPIPKSYPIFGSAFSLLANFHRRIQWTSDILQTIPSS 76 Query: 255 -FAAHMGLTGVRFFLTCDPSNVRHIFISNSINYPRGEE-YADIFDVLGDGIFNADGESWR 428 F H G R T P+ V+HI +N Y +G Y I D LGDGIFNADGESW+ Sbjct: 77 TFVLHRPF-GARQVFTAQPAVVQHILRTNFTCYGKGLTFYQSINDFLGDGIFNADGESWK 135 Query: 429 RQRAKSQLIMASPRFRSFSARCTRDKVERSLLPFLAHAADVGARCDLHDVLLRLMFDMTC 608 QR S + R F ++ L+P L+ A++ D D+L RL FD C Sbjct: 136 FQRQISSHEFNTRSLRKFVETVVDVELSDRLVPVLSQASNSQTTLDFQDILQRLTFDNIC 195 Query: 609 NLVFGVDPGCLQIGLPSLPLARAMDDVLETLFLR-HVIPPACWRLMYRYGFGPEKKMAVA 785 + FG DP L LP +P A+A D+ + R + + P W++ G E+++ A Sbjct: 196 MIAFGYDPEYLLPSLPEIPFAKAFDESSQLSIERLNALIPLLWKVKRFLNIGVERQLKEA 255 Query: 786 RRIIDRFAADTIVKRRYSGHKLRG-EGITESSDILSFFICNDDASEHSDE-FLRDTAVNL 959 + R A IVK + K + + +ES D+LS F+ +S HSDE F+ D +++ Sbjct: 256 VAEV-RGLATKIVKNKKKELKEKALQSESESVDLLSRFL----SSGHSDESFVTDMVISI 310 Query: 960 LFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLH 1139 + AGRDTT A L+WFF+LL ++ VE IL E+ + D E+ MVY H Sbjct: 311 ILAGRDTTSAALTWFFWLLSKHSHVENEILKEITGKSETVGYD--------EVKDMVYTH 362 Query: 1140 AALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFS 1319 AALCE +RLYP +P+ K A H+DVLP G +K G ++ + Y+MGR E +WG D EF Sbjct: 363 AALCESMRLYPPLPVDTKVAVHDDVLPDGTLVKKGWRVTYHIYAMGRSEKIWGPDWAEFR 422 Query: 1320 PERWITDD--GKLRHQ--PPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLETVP 1487 PERW++ D GK Y + F AGPR C+GKE+AF QMK V A ++ F + Sbjct: 423 PERWLSRDEVGKWSFVGIDYYSYPVFQAGPRVCIGKEMAFLQMKRVVAGIMGRFRVVPAM 482 Query: 1488 GHTVKPKLS--IVLHMKNGLAVTVKRRN 1565 ++P+ + MK G V +++R+ Sbjct: 483 VEGIEPEYTAHFTSVMKGGFPVKIEKRS 510
>O81117:C94A1_VICSA Cytochrome P450 94A1 - Vicia sativa (Spring vetch) (Tare)| Length = 514 Score = 268 bits (686), Expect = 4e-71 Identities = 165/481 (34%), Positives = 250/481 (51%), Gaps = 10/481 (2%) Frame = +3 Query: 153 PTEWPLLGHLLSTLANVSNLHDWATGVLATTRYNFAAHMGLTGVRFFLTCDPSNVRHIFI 332 P +PL+G LS N+ W + ++ + G G R +T +PS V+HI Sbjct: 48 PKSYPLIGSYLSFRKNLHRRIQWLSDIVQISPSATFQLDGTLGKRQIITGNPSTVQHILK 107 Query: 333 SNSINYPRGEEYAD-IFDVLGDGIFNADGESWRRQRAKSQLIMASPRFRSFSARCTRDKV 509 + NY +G + + + D LG GIFN +G +W+ QR + + R+F ++ Sbjct: 108 NQFSNYQKGTTFTNTLSDFLGTGIFNTNGPNWKFQRQVASHEFNTKSIRNFVEHIVDTEL 167 Query: 510 ERSLLPFLAHAADVGARCDLHDVLLRLMFDMTCNLVFGVDPGCLQIGLPSLPLARAMDDV 689 L+P L + D D+L R FD CN+ FG DP L A A +D Sbjct: 168 TNRLIPILTSSTQTNNILDFQDILQRFTFDNICNIAFGYDPEYLTPSTNRSKFAEAYEDA 227 Query: 690 LETLFLRHVIP-PACWRLMYRYGFGPEKKMAVARRIIDRFAADTIVKRRYSGHKLRGEGI 866 E R +P P W++ + G EK++ A + FA + +++ +L + Sbjct: 228 TEISSKRFRLPLPIIWKIKKYFNIGSEKRLKEAVTEVRSFAKKLVREKK---RELEEKSS 284 Query: 867 TESSDILSFFICNDDASEHSDE-FLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQM 1043 E+ D+LS F+ +S HSDE F+ D ++ + AG+DTT A L+WFF+LL +NPRVE+ Sbjct: 285 LETEDMLSRFL----SSGHSDEDFVADIVISFILAGKDTTSAALTWFFWLLWKNPRVEEE 340 Query: 1044 ILDELAPIAARKKVDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPS 1223 I++EL+ K +++V D E+ MVY HAAL E +RLYP VP+ K A ++DVLP Sbjct: 341 IVNELS------KKSELMVYD--EVKEMVYTHAALSESMRLYPPVPMDSKEAVNDDVLPD 392 Query: 1224 GHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWITDD---GK--LRHQPPYKFIAFN 1388 G +K G + + Y+MGRM+ +WG D EF PERW+ D GK + Y + F Sbjct: 393 GWVVKKGTIVTYHVYAMGRMKSLWGDDWAEFRPERWLEKDEVNGKWVFVGRDSYSYPVFQ 452 Query: 1389 AGPRTCLGKEVAFTQMKTVAATVLWNFTLETVPGHTVKPKLSIVL--HMKNGLAVTVKRR 1562 AGPR CLGKE+AF QMK + A ++ F + +P L M+ G VT+++R Sbjct: 453 AGPRVCLGKEMAFMQMKRIVAGIVGKFKVVPEAHLAQEPGFISFLSSQMEGGFPVTIQKR 512 Query: 1563 N 1565 + Sbjct: 513 D 513
>P30607:CP52B_CANTR Cytochrome P450 52A2 - Candida tropicalis (Yeast)| Length = 522 Score = 138 bits (348), Expect = 7e-32 Identities = 115/420 (27%), Positives = 184/420 (43%), Gaps = 20/420 (4%) Frame = +3 Query: 297 TCDPSNVRHIFISNSINYPRGEEYADIFDVLGDGIFNADGESWRRQRAKSQLIMASPRFR 476 T +P N++ I + ++ G ++ +LGDGIF DG W+ R+ M P+F Sbjct: 102 TLEPDNIKAILATQFNDFSLGTRHSHFAPLLGDGIFTLDGAGWKHSRS-----MLRPQFA 156 Query: 477 SFSARCTRDKVERSLLPFLAHAADV-GARCDLHDVLLRLMFDMTCNLVFGVDPGCLQ--- 644 + +E + F H G D+ ++ RL D +FG L+ Sbjct: 157 REQVSHVK-LLEPHMQVFFKHIRKHHGQTFDIQELFFRLTVDSATEFLFGESVESLRDES 215 Query: 645 IGLPSLPL--------ARAMDDVLETLFLRHVIPPACWRLMYRYGFGPEKKMAVARRIID 800 IG+ + L A A + L R ++ W L KK + Sbjct: 216 IGMLNDALDFDGKAGFADAFNYSQNYLASRALMQQMYWILN-------GKKFKECNAKVH 268 Query: 801 RFAADTIVKRRYSGHKLRGEGITESSDILSFFICNDDASEHSDEFLRDTAVNLLFAGRDT 980 +FA D V++ +L + + + + F+ + LRD +N+L AGRDT Sbjct: 269 KFA-DYYVEKAL---ELTPDQLEKQDGYV--FLYELVKQTRDRQVLRDQLLNILVAGRDT 322 Query: 981 TGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAALCECL 1160 T +LS+ F+ L PRV + +E+ + + + L S YL A L ECL Sbjct: 323 TAGLLSFVFFELARTPRVANKLREEIEDKFGLGQDARVEEISFESLKSCEYLKAVLNECL 382 Query: 1161 RLYPSVPITHKAATHNDVLPSGHE--------IKAGDKILVYSYSMGRMEGVWGKDCMEF 1316 RLYPSVP + AT N LP G ++ G ++ Y+ R + ++G+D +EF Sbjct: 383 RLYPSVPQNFRVATRNTTLPRGGGKDGLSPVLVRKGQTVMYSVYAAHRNKQIYGEDALEF 442 Query: 1317 SPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLETVPGHT 1496 PERW + K + + F+ FN GPR CLG++ A T+ V +L F+ T+ +T Sbjct: 443 RPERWFEPETK---KLGWAFLPFNGGPRICLGQQFALTEASYVTVRLLQEFSHLTMDPNT 499
>P16141:CP52D_CANMA Cytochrome P450 52A4 - Candida maltosa (Yeast)| Length = 538 Score = 136 bits (342), Expect = 3e-31 Identities = 113/439 (25%), Positives = 186/439 (42%), Gaps = 12/439 (2%) Frame = +3 Query: 273 LTGVRFFLTCDPSNVRHIFISNSINYPRGEEYADIFDVLGDGIFNADGESWRRQRAKSQL 452 + G+ T DP NV+ I + ++ G + ++ +LGDGIF DG W+ RA Sbjct: 110 IMGLNIIETTDPENVKAILATQFNDFSLGTRHDFLYSLLGDGIFTLDGAGWKHSRA---- 165 Query: 453 IMASPRFRSFSARCTRDKVERSLLPFLAHAADVGARCDLHDVLLRLMFDMTCNLVFGVDP 632 M P+F + + F G D+ ++ RL D + +FG Sbjct: 166 -MLRPQFAREQVAHVKLLEPHVQVLFKHVRKSQGKTFDIQELFFRLTVDSSTEFLFGGSV 224 Query: 633 GCLQ---IGL-PSLPLARAMDDVLETLFLRHVIPPACWRLMYRYGFGPEKKMAVARRIID 800 L+ IG+ PS ++ + + L Y K + + + Sbjct: 225 ESLRDASIGMVPSTKNIAGREEFADAFNYSQTYNAYRFLLQQFYWILNGSKFNKSIKTVH 284 Query: 801 RFAADTIVKRRYSGHKLRGEGITESSDILSFFICNDDASEHSDEFLRDTAVNLLFAGRDT 980 +FA D V++ S L + + + + F+ + LRD +N+L AGRDT Sbjct: 285 KFA-DFYVQKALS---LTDDDLEKQEGYV--FLYELAKQTRDPKVLRDQLLNILVAGRDT 338 Query: 981 TGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAALCECL 1160 T +LS+ F+ L NP V + + +E+ K+ + + L YL A + E L Sbjct: 339 TAGLLSFLFFELSRNPTVFEKLKEEIHNRFGAKEDARVEEITFESLKLCEYLKACVNEAL 398 Query: 1161 RLYPSVPITHKAATHNDVLPSGH--------EIKAGDKILVYSYSMGRMEGVWGKDCMEF 1316 R+YPSVP + AT N LP G IK G ++ + R ++G+D F Sbjct: 399 RVYPSVPHNFRVATRNTTLPRGGGKDGMSPIAIKKGQNVMYTISATHRDPSIYGEDANVF 458 Query: 1317 SPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLETVPGHT 1496 PERW + + + + ++ FN GPR CLG++ A T+ V +L F T +T Sbjct: 459 RPERWFEPETR---KLGWAYVPFNGGPRICLGQQFALTEASYVTVRLLQEFHTLTQDANT 515 Query: 1497 VKPKLSIVLHMKNGLAVTV 1553 P ++N L V++ Sbjct: 516 RYPP-----RLQNSLTVSL 529
>P24458:CP52E_CANMA Cytochrome P450 52A5 - Candida maltosa (Yeast)| Length = 523 Score = 135 bits (340), Expect = 6e-31 Identities = 113/461 (24%), Positives = 197/461 (42%), Gaps = 34/461 (7%) Frame = +3 Query: 282 VRFFLTCDPSNVRHIFISNSINYPRGEEYADIFDVLGDGIFNADGESWRRQRAKSQLIMA 461 ++ LT DP N++ + + ++ G +A +LGDGIF DGE W+ RA M Sbjct: 98 LKIVLTVDPENIKAVLATQFNDFALGARHAHFDPLLGDGIFTLDGEGWKHSRA-----ML 152 Query: 462 SPRFRSFSARCTRDKVE--RSLLPFLAHAA-----DVGARCDLHDVLLRLMFDMTCNLVF 620 P+F R+++ ++L P + A + G DL ++ R D +F Sbjct: 153 RPQF-------AREQIAHVKALEPHVQVLAKQIKLNKGETFDLQELFFRFTVDTATEFLF 205 Query: 621 GVDPGCL---QIGLP---SLPLARAMDDVLETLFLRHVIPPACWRLMYRYGFGPE----- 767 G L ++G+P ++P T +H + + M+ + P+ Sbjct: 206 GESVHSLYDEKLGVPPPNNIPGRENFAKAFNTS--QHYLATRTYSQMFYFLTNPKEFRDC 263 Query: 768 --KKMAVARRIIDRF---AADTIVKRRYSGHKLRGEGITESSDILSFFICNDDASEHSDE 932 K +A+ +++ + D + ++ G+ E + ++ D + Sbjct: 264 NAKVHKLAQYFVNKALDASEDEVAEKSKGGYVFLYELVKQTRD---------------PK 308 Query: 933 FLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAP---IAARKKVDDMVVL 1103 L+D +N++ AGRDTT +LS+ + L NP++ + +E+ + +VD+ + Sbjct: 309 VLQDQLLNIMVAGRDTTAGLLSFAMFELARNPKIWNKLREEIEVNFGLGEEARVDE---I 365 Query: 1104 DASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHE--------IKAGDKILV 1259 L YL A L E LR+YPSVP+ + AT + LP G + G ++ Sbjct: 366 SFETLKKCEYLKAVLNETLRMYPSVPVNFRTATRDTTLPRGGGKDGTSPIFVPKGSSVVY 425 Query: 1260 YSYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMK 1439 Y R+E +GKD EF PERW + + + ++ FN GPR CLG++ A T+ Sbjct: 426 TVYKTHRLEEYYGKDAYEFRPERWFEPSTR---KLGWAYVPFNGGPRICLGQQFALTEAS 482 Query: 1440 TVAATVLWNFTLETVPGHTVKPKLSIVLHMKNGLAVTVKRR 1562 V + F T P I L M + V + + Sbjct: 483 YVITRLAQMFEHLESKDETYPPNKCIHLTMNHNEGVFISAK 523
>P30608:CP52F_CANTR Cytochrome P450 52A6 - Candida tropicalis (Yeast)| Length = 524 Score = 134 bits (336), Expect = 2e-30 Identities = 118/460 (25%), Positives = 198/460 (43%), Gaps = 25/460 (5%) Frame = +3 Query: 252 NFAAHMGLTG-VRFFLTCDPSNVRHIFISNSINYPRGEEYADIFDVLGDGIFNADGESWR 428 N +M + G ++ LT N++ + + ++ G +A + +LGDGIF DGE W+ Sbjct: 88 NHTFYMSIIGALKIVLTVIQENIKAVLATQFTDFSLGTRHAHFYPLLGDGIFTLDGEGWK 147 Query: 429 RQRAKSQLIMASPRFRSFSARCTRDKV--ERSLLPFLAHAA-----DVGARCDLHDVLLR 587 RA M P+F RD++ ++L P + A + G D+ ++ R Sbjct: 148 HSRA-----MLRPQF-------ARDQIGHVKALEPHIQILAKQIKLNKGKTFDIQELFFR 195 Query: 588 LMFDMTCNLVFGVDPGCL---QIGLPSLPLARAMDDVLETLF--LRHVIPPACWRLMYRY 752 D +FG L ++G+P+ P D T F +H + + + + Sbjct: 196 FTVDTATEFLFGESVHSLYDEKLGIPT-PNEIPGRDNFATAFNTSQHYLATRTYSQTFYF 254 Query: 753 GFGPEKKMAVARRIIDRFAADTIVKRRYSGHKLRGEGITESSDILSFFICNDDASEHSDE 932 P++ ++ + A V + + E I E S F+ + Sbjct: 255 LTNPKEFRDCNAKV--HYLAKYFVNKALN---FTPEEIEEKSKSGYVFLYELVKQTRDPK 309 Query: 933 FLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELA---PIAARKKVDDMVVL 1103 L+D +N++ AGRDTT +LS+ + L +P + + +E+ + +V+++ Sbjct: 310 VLQDQLLNIMVAGRDTTAGLLSFAMFELARHPEIWSKLREEIEVNFGVGEESRVEEITF- 368 Query: 1104 DASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHE--------IKAGDKILV 1259 L YL A L E LR+YPSVP+ + AT + LP G I G + Sbjct: 369 --ESLKRCEYLKAILNETLRMYPSVPVNSRTATRDTTLPRGGGPNGTDPIFIPKGSTVAY 426 Query: 1260 YSYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMK 1439 Y R+E +GKD +F PERW K + + ++ FN GPR CLG++ A T+ Sbjct: 427 IVYKTHRLEEYYGKDADDFRPERWFEPSTK---KLGWAYVPFNGGPRICLGQQFALTEAS 483 Query: 1440 TVAATVLWNF-TLETVPGHTVKPKLSIVLHMKNGLAVTVK 1556 V ++ F T+ + P P I L M + V VK Sbjct: 484 YVITRLVQMFETVSSPPDVEYPPPKCIHLTMSHDDGVFVK 523
>P16496:CP52C_CANMA Cytochrome P450 52A3 - Candida maltosa (Yeast)| Length = 523 Score = 132 bits (332), Expect = 5e-30 Identities = 113/464 (24%), Positives = 201/464 (43%), Gaps = 27/464 (5%) Frame = +3 Query: 252 NFAAHMGLTGV-RFFLTCDPSNVRHIFISNSINYPRGEEYADIFDVLGDGIFNADGESWR 428 N +++M + GV + T DP N++ + + ++ G +A +LGDGIF DGE W+ Sbjct: 87 NLSSYMTVAGVLKIVFTVDPENIKAVLATQFNDFALGARHAHFDPLLGDGIFTLDGEGWK 146 Query: 429 RQRAKSQLIMASPRFRSFSARCTRDKVE--RSLLPFLAHAA-----DVGARCDLHDVLLR 587 RA M P+F R+++ ++L P + A + G DL ++ R Sbjct: 147 LSRA-----MLRPQF-------AREQIAHVKALEPHVQILAKQIKLNKGKTFDLQELFFR 194 Query: 588 LMFDMTCNLVFGVDPGCL---QIGLPS---LPLARAMDDVLETLFLRHVIPPACWRLMYR 749 D +FG L ++G+P+ +P + T +H + + ++ Sbjct: 195 FTVDTATEFLFGESVHSLYDEKLGIPAPNDIPGRENFAEAFNTS--QHYLATRTYSQIFY 252 Query: 750 YGFGPEKKMAVARRI--IDRFAADTIVKRRYSGHKLRGEGITESSDILSFFICNDDASEH 923 + P++ ++ + ++ +T + + + E S F+ Sbjct: 253 WLTNPKEFRDCNAKVHKLAQYFVNTALNATE-------KEVEEKSKGGYVFLYELVKQTR 305 Query: 924 SDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAP---IAARKKVDDM 1094 + L+D +N++ AGRDTT +LS+ + L NP++ + +E+ + +VD+ Sbjct: 306 DPKVLQDQLLNIMVAGRDTTAGLLSFAMFELARNPKIWNKLREEVEVNFGLGDEARVDE- 364 Query: 1095 VVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHE--------IKAGDK 1250 + L YL A L E LR+YPSVPI + AT + LP G + G Sbjct: 365 --ISFETLKKCEYLKAVLNETLRMYPSVPINFRTATRDTTLPRGGGKDGNSPIFVPKGSS 422 Query: 1251 ILVYSYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFT 1430 ++ Y R++ +G+D EF PERW + + + ++ FN GPR CLG++ A T Sbjct: 423 VVYSVYKTHRLKQFYGEDAYEFRPERWFEPSTR---KLGWAYLPFNGGPRICLGQQFALT 479 Query: 1431 QMKTVAATVLWNFTLETVPGHTVKPKLSIVLHMKNGLAVTVKRR 1562 + V A + F T P I L M + V + + Sbjct: 480 EASYVIARLAQMFEHLESKDETYPPNKCIHLTMNHNEGVFISAK 523
>P10615:CP52A_CANTR Cytochrome P450 52A1 - Candida tropicalis (Yeast)| Length = 543 Score = 131 bits (330), Expect = 8e-30 Identities = 115/438 (26%), Positives = 184/438 (42%), Gaps = 21/438 (4%) Frame = +3 Query: 273 LTGVRFFLTCDPSNVRHIFISNSINYPRGEEYADIFDVLGDGIFNADGESWRRQRAKSQL 452 + G+ T DP NV+ I + ++ G + ++ +LGDGIF DG W+ R Sbjct: 112 ILGIPLIETKDPENVKAILATQFNDFSLGTRHDFLYSLLGDGIFTLDGAGWKHSRT---- 167 Query: 453 IMASPRFRSFSARCTRDKVERSLLPFLAHAADVGARCDLHDVLLRLMFDMTCNLVFGVDP 632 M P+F + + F G D+ ++ RL D + G Sbjct: 168 -MLRPQFAREQVSHVKLLEPHMQVLFKHIRKHHGQTFDIQELFFRLTVDSATEFLLGESA 226 Query: 633 GCLQ---IGLPSL--------PLARAMDDVLETLFLRHVIPPACWRLMYRYGFGPEKKMA 779 L+ +GL A A + R ++ W L G E + + Sbjct: 227 ESLRDESVGLTPTTKDFDGRNEFADAFNYSQTNQAYRFLLQQMYWILN-----GSEFRKS 281 Query: 780 VARRIIDRFAADTIVKRRYSGHKLRGEGITESSDILSFFICNDDASEHSD-EFLRDTAVN 956 +A I+ +FA + K +L E + + + F + A + D + LRD +N Sbjct: 282 IA--IVHKFADHYVQK----ALELTDEDLEKKEGYVFLF---ELAKQTRDPKVLRDQLLN 332 Query: 957 LLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYL 1136 +L AGRDTT +LS+ F+ L NP + + +E+ + + + L S YL Sbjct: 333 ILVAGRDTTAGLLSFLFFELSRNPEIFAKLREEIENKFGLGQDARVEEISFETLKSCEYL 392 Query: 1137 HAALCECLRLYPSVPITHKAATHNDVLPSGH--------EIKAGDKILVYSYSMGRMEGV 1292 A + E LR+YPSVP + AT N LP G IK G ++ + R + + Sbjct: 393 KAVINETLRIYPSVPHNFRVATRNTTLPRGGGEGGLSPIAIKKGQVVMYTILATHRDKDI 452 Query: 1293 WGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNF- 1469 +G+D F PERW + + + + ++ FN GPR CLG++ A T+ V +L F Sbjct: 453 YGEDAYVFRPERWFEPETR---KLGWAYVPFNGGPRICLGQQFALTEASYVTVRLLQEFG 509 Query: 1470 TLETVPGHTVKPKLSIVL 1523 L+ P PKL L Sbjct: 510 NLKQDPNTEYPPKLQNTL 527
>Q12588:CP52J_CANMA Cytochrome P450 52A10 - Candida maltosa (Yeast)| Length = 519 Score = 130 bits (327), Expect = 2e-29 Identities = 118/437 (27%), Positives = 179/437 (40%), Gaps = 25/437 (5%) Frame = +3 Query: 279 GVRFFLTCDPSNVRHIFISNSINYPRGEEYADIFDVLGDGIFNADGESWRRQRAK----- 443 G++F T DP N++ + + Y G+ + +LG GIF DG W+ RA Sbjct: 93 GMQFIATKDPENIKAMLATQFNEYTLGQRLNFLAPLLGKGIFTLDGNGWKHSRAMLRPQF 152 Query: 444 -----SQLIMASPRFRSFSARCTRDKVERSLLPFLAHAADVGARCDLHDVLLRLMFDMTC 608 + M P F+ ++K G D+ ++ R D Sbjct: 153 SRDQIGHVKMLEPHFQLLKKHIIKNK---------------GTFFDIQELFFRFTVDSAT 197 Query: 609 NLVFGVDPGCLQ---IGLPSLPLARA-MDDVLETLFLRHVIPPACWRLMYRYGFGPEKKM 776 +FG L+ IG + A D E V L Y Sbjct: 198 EFLFGESVSSLKDESIGYDQEEIDFAGRKDFAEAFNKSQVYLSTRTLLQLLYWLVNSADF 257 Query: 777 AVARRIIDRFAADTIVKRRYSGHKLRGEGITESSDILSFFICNDDASEHSDEF-LRDTAV 953 +I+ +F+ D +K+ + E + + S S+ + A + D LRD ++ Sbjct: 258 KRCNKIVHKFS-DYYIKKALTATP---EELEKHS---SYIFLYELAKQTRDPIVLRDQSL 310 Query: 954 NLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVY 1133 N+L AGRDTT +LS+ + L NP V + E+ + + L Y Sbjct: 311 NILLAGRDTTAGLLSFAVFELGRNPEVWSKLRQEIGHKFGLDSYSRVEDISFELLKLCEY 370 Query: 1134 LHAALCECLRLYPSVPITHKAATHNDVLPSGHE--------IKAGDKILVYSYSMGRMEG 1289 L A L E LRLYPSVP + A N LP G ++ G ++ Y++ R E Sbjct: 371 LKAVLNETLRLYPSVPRNARFAAKNTTLPHGGGPDGMSPILVRKGQTVMYSVYALQRDEK 430 Query: 1290 VWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNF 1469 +GKD EF PERW + + + + F+ FN GPR CLG++ A T+ V A ++ +F Sbjct: 431 YYGKDANEFRPERWFEPEVR---KLGWAFLPFNGGPRICLGQQFALTEASYVLARLIQSF 487 Query: 1470 -TLETVPGHTVKP-KLS 1514 TLE P P KLS Sbjct: 488 ETLELSPEAAYPPAKLS 504
>Q9Y757:CP52L_DEBHA Cytochrome P450 52A12 - Debaryomyces hansenii (Yeast) (Torulaspora| hansenii) Length = 519 Score = 129 bits (325), Expect = 3e-29 Identities = 116/419 (27%), Positives = 174/419 (41%), Gaps = 26/419 (6%) Frame = +3 Query: 273 LTGVRFFLTCDPSNVRHIFISNSINYPRGEEYADIFDVLGDGIFNADGESWRRQRAKSQL 452 + G T +P N++ + + ++ G +A +LGDGIF DG W+ RA Sbjct: 90 IAGTPVISTKNPENIKALLATQFSDFALGTRHAQFKPLLGDGIFTLDGSGWKHSRA---- 145 Query: 453 IMASPRFRSFSARCTRDKVE--RSLLPFLAHAAD-----VGARCDLHDVLLRLMFDMTCN 611 M P+F R++V +SL P + A G D+ + RL D Sbjct: 146 -MLRPQF-------AREQVAHVKSLEPHIQMLAKHVRRAKGGAFDVQSLFFRLTVDSATE 197 Query: 612 LVFGVDPGCLQ---IGLPS--------LPLARAMDDVLETLFLRHVIPPACWRLMYRYGF 758 +FG LQ IG+ A A + L +R + A Y Sbjct: 198 FLFGESVESLQDESIGMAKDAVDFDGKAGFAEAFNTAQVYLSIRSLAQKA-------YFL 250 Query: 759 GPEKKMAVARRIIDRFAADTIVKRRYSGHKLRGEGITESSDILSFFICNDDASEHSDEFL 938 K+ + + +FA D V++ + E ++ I + + H L Sbjct: 251 VNNKEFRSSNEKVHKFA-DYYVQKALNSSPEELEKHSQDGYIFLYELVKQTRDPH---VL 306 Query: 939 RDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASEL 1118 RD +N+L AGRDTT +LS+ FY L NP+V + +E+ + + + L Sbjct: 307 RDQLLNILLAGRDTTAGLLSFTFYELARNPQVWLKLKEEIYEKFGKGDDARLEDITFESL 366 Query: 1119 SSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHE--------IKAGDKILVYSYSM 1274 YL A L E LRLYPSVP + A + LP G I G + Y+M Sbjct: 367 KKCEYLKALLNEVLRLYPSVPQNFRVAQKDTSLPRGGGPNRDQPIFIAKGQTVTYTVYAM 426 Query: 1275 GRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAA 1451 R E +GKD F PERW + + + + F+ FN GPR CLG++ A T+ V A Sbjct: 427 HRDEQFYGKDSEVFRPERWFEPETR---KLGWAFLPFNGGPRICLGQQFALTEASYVIA 482
>Q9Y758:CP52M_DEBHA Cytochrome P450 52A13 - Debaryomyces hansenii (Yeast) (Torulaspora| hansenii) Length = 519 Score = 129 bits (324), Expect = 4e-29 Identities = 123/441 (27%), Positives = 190/441 (43%), Gaps = 22/441 (4%) Frame = +3 Query: 273 LTGVRFFLTCDPSNVRHIFISNSINYPRGEEYADIFDVLGDGIFNADGESWRRQRAKSQL 452 + GV +T DP N++ + + ++ G +A +LGDGIF DG W++ R+ Sbjct: 92 IVGVPVIITRDPENMKAVLATQFNDFALGTRHAHFKPLLGDGIFTLDGNGWKQSRS---- 147 Query: 453 IMASPRFRSFSARCTRDKVE--RSLLPFLAHAADV-----GARCDLHDVLLRLMFDMTCN 611 M P+F +R++V ++L P L A G ++ D+ +L D Sbjct: 148 -MLRPQF-------SREQVAHVQALEPHLQRLAKHIRLADGETINIQDLFFKLTVDTATE 199 Query: 612 LVFGVDPGCLQIGLPSLPLARAMD--DVLETLF--LRHVIPPACWRLMYRYGFGPEKKMA 779 +FG L+ + P D F + + + M+ + Sbjct: 200 FLFGQSVYSLKDAAINDPPTEDFDGRSSFANSFNTAQTYLGTRAYLQMFYFIVNNSDFRK 259 Query: 780 VARRIIDRFAADTIVKRRYSGHKLRGEGITESSDILSFFICNDDASEHSDEFLRDTAVNL 959 +++ D F + K G + E + + S+ F+ + L+D +N+ Sbjct: 260 CCKQVHD-FTRFYVQK----GLDMTPEELEKKSENGYVFLYELVKQTRDPKVLQDQLLNI 314 Query: 960 LFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDAS--ELSSMVY 1133 L AGRDTT +LS+ F+ L +PRV + +E+ A K DD V + + L Y Sbjct: 315 LLAGRDTTAGLLSFTFFELARHPRVFNKLKEEI--YEAFGKGDDARVSEITFESLKKCEY 372 Query: 1134 LHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILV-------YS-YSMGRMEG 1289 L + E LRLYPSVP+ + AT LP G I V YS YS RME Sbjct: 373 LKWVMNEMLRLYPSVPVNFRVATKRTTLPRGGGPDGNSPIYVGKGTTVAYSVYSTHRMEE 432 Query: 1290 VWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNF 1469 +GKD EF PERW + KL + ++ FN GPR CLG++ A T+ + +L F Sbjct: 433 YYGKDADEFKPERW-AESRKL----GWAYVPFNGGPRICLGQQFALTEASYIVTRLLQMF 487 Query: 1470 -TLETVPGHTVKPKLSIVLHM 1529 LE P S+ L M Sbjct: 488 DKLELHDDRPYPPAKSVHLTM 508
>P43083:CP52V_CANAP Cytochrome P450 52E1 - Candida apicola (Yeast)| Length = 519 Score = 129 bits (323), Expect = 5e-29 Identities = 114/446 (25%), Positives = 185/446 (41%), Gaps = 26/446 (5%) Frame = +3 Query: 273 LTGVRFFLTCDPSNVRHIFISNSINYPRGEEYADIFDVLGDGIFNADGESWRRQRAKSQL 452 L G R+ +T +P N++ + ++ +Y G Y ++ +LG+GIF G+ W+ RA Sbjct: 88 LAGQRWLVTLEPENIKTVLATSFKDYSLGFRYDIMYGLLGNGIFTLSGDGWKHSRA---- 143 Query: 453 IMASPRFRSFSARCTRDKVERSLLPFLAHAADVGARCDLHDVLLRLMFDMTCNLVFG--- 623 + P+F S + + + + + G D + L D +FG Sbjct: 144 -LLRPQF-SREQVSHLESMRTHINLMINNHFKGGQVVDAQALYHNLTIDTATEFLFGEST 201 Query: 624 --VDPGCLQIGLP-------SLPLARAMDDVLETLFLRHVIPPACWRLMYRYGFGPEKKM 776 +DP Q GLP A A LE L +R VI A W L++ F + Sbjct: 202 NTLDPDLAQQGLPGPKGLVTGEQFAEAFTSALEILSVR-VIVGAAWFLIWTPKFW--RSC 258 Query: 777 AVARRIIDRFAADTIVKRRYSGHKLRGEGITESSDILSFFICNDDASEHSD-EFLRDTAV 953 V ID F +K + + + + + E SD +RD A+ Sbjct: 259 KVCHNFIDYFV-----------YKALATPMEKDQEADRYVFIRELTKETSDPRVIRDQAL 307 Query: 954 NLLFAGRDTTGAVLSWFFYLLCENPRV----EQMILDELAPIAARKKVDDMVVLDASELS 1121 N+L AGRDTT +LS+ Y L P V + +L E D+ +L Sbjct: 308 NILLAGRDTTAGLLSFITYYLGAYPEVYAELREAVLSEFGS-------TDVETPTFEQLK 360 Query: 1122 SMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHE--------IKAGDKILVYSYSMG 1277 L + E LRL+P+VP+ + A + LP+G + G + +YSM Sbjct: 361 QCKVLQNVIREVLRLHPNVPLNFRQAIVDTKLPTGGGPNGDQPVFVPKGQNVFYSTYSMQ 420 Query: 1278 RMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATV 1457 R +WG D F P+RW ++ + + +I FN GPR CLG++ A T+ + Sbjct: 421 RRTDIWGPDATTFRPDRW--NEPREALASGWDYIPFNGGPRICLGQQFALTEASYTIVRI 478 Query: 1458 LWNFT-LETVPGHTVKPKLSIVLHMK 1532 F+ +E + + K S+ M+ Sbjct: 479 CQEFSRIEVLHPDVITSKNSMKQRMR 504
>Q12589:CP52K_CANMA Cytochrome P450 52A11 - Candida maltosa (Yeast)| Length = 519 Score = 129 bits (323), Expect = 5e-29 Identities = 113/433 (26%), Positives = 179/433 (41%), Gaps = 24/433 (5%) Frame = +3 Query: 279 GVRFFLTCDPSNVRHIFISNSINYPRGEEYADIFDVLGDGIFNADGESWRRQRAK----- 443 G++F T DP N++ + + ++ G+ + +LG GIF DGE W+ RA Sbjct: 93 GMQFIATKDPENIKAMLATQFNDFTLGQRLSYFAPLLGKGIFTLDGEGWKHSRAMLRPQF 152 Query: 444 -----SQLIMASPRFRSFSARCTRDKVERSLLPFLAHAADVGARCDLHDVLLRLMFDMTC 608 + M P F+ ++K G+ D+ ++ R D Sbjct: 153 SRDQVGHVKMLEPHFQLLKKHIIKNK---------------GSFFDIQELFFRFTVDSAT 197 Query: 609 NLVFGVDPGCLQ---IGLPSLPLARA-MDDVLETLFLRHVIPPACWRLMYRYGFGPEKKM 776 +FG L+ IG + A D E V L Y Sbjct: 198 EFLFGESVSSLKDESIGYDQEEIDFAGRKDFAEAFNKSQVYLSTRSLLQLLYWLVNSSDF 257 Query: 777 AVARRIIDRFAADTIVKRRYSGHKLRGEGITESSDILSFFICNDDASEHSDEF-LRDTAV 953 +I+ +F+ D +K+ + E + + S S+ + A + D LRD ++ Sbjct: 258 KRCNKIVHKFS-DYYIKKALTATP---EELEKHS---SYIFLYELAKQTRDPIVLRDQSL 310 Query: 954 NLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVY 1133 N+L AGRDTT +LS+ + L NP V + +E+ + + L Y Sbjct: 311 NILLAGRDTTAGLLSFAVFELGRNPEVWSKLREEIGDKFGLDPDSRIEDISFELLKLCEY 370 Query: 1134 LHAALCECLRLYPSVPITHKAATHNDVLPSGHE--------IKAGDKILVYSYSMGRMEG 1289 L A + E LRLYPSVP + A N LP G ++ G ++ Y++ R E Sbjct: 371 LKAVINETLRLYPSVPRNGRFAAANTTLPHGGGPDGMSPILVRKGQTVMYSVYALQRDEK 430 Query: 1290 VWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNF 1469 +GKD EF PERW + + + + F+ FN GPR CLG++ A T+ V ++ +F Sbjct: 431 YYGKDANEFRPERWFEPEVR---KLGWAFLPFNGGPRICLGQQFALTEASYVLVRLIQSF 487 Query: 1470 -TLETVPGHTVKP 1505 TLE P P Sbjct: 488 ETLELSPDAPYPP 500
>P77900:CP132_MYCTU Putative cytochrome P450 132 - Mycobacterium tuberculosis| Length = 461 Score = 127 bits (318), Expect = 2e-28 Identities = 116/463 (25%), Positives = 202/463 (43%), Gaps = 14/463 (3%) Frame = +3 Query: 216 DWATGVLATTRYNFAAHMGLTGVRFFLTCDPSNVRHIFISNSINYPRGEEYADIFDVLGD 395 D G L R + G RF P V H+ + Y + +EY I G Sbjct: 32 DAGDGFLGRLRGSDITRFRCAGRRFVSISHPDYVDHVLHEARLKYVKSDEYGPIRATAGL 91 Query: 396 GIFNADGESWRRQRAKSQLIMASPRFRSFSARCTRDKVERSLLPF--LAHAADVGARCDL 569 + +G+SW R R +F+ R R V + P + A GA+ D+ Sbjct: 92 NLLTDEGDSWARHRGALN--------STFARRHLRGLVGLMIDPIADVTAARVPGAQFDM 143 Query: 570 HDVLLRLMFDMTCNLVFGVDPGCLQIGLPSLP---LARAMDDVLETLFLRHVIPPACWRL 740 H ++ + N +F D G L + L L RA + LE L L ++P + Sbjct: 144 HQSMVETTLRVVANALFSQDFGPLVQSMHDLATRGLRRA--EKLERLGLWGLMPRTVYDT 201 Query: 741 MYRYGFG------PEKKMAVARRIIDRFAADTIVKRRYSGHKLRGEGITESSDILSFFIC 902 + + P ++M +DR A ++++ RR + T S+D+L+ + Sbjct: 202 LIWCIYSGVHLPPPLREMQEITLTLDR-AINSVIDRRLAEP-------TNSADLLNVLL- 252 Query: 903 NDDASEHSDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKK 1082 + D + +RD A+ + AG +TT +SWF+YL+ NP+ +L EL + ++ Sbjct: 253 SADGGIWPRQRVRDEALTFMLAGHETTANAMSWFWYLMALNPQARDHMLTELDDVLGMRR 312 Query: 1083 VDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVY 1262 A +L + + A L E R + SV I + A +D++ GH I+ G +++ Sbjct: 313 PT------ADDLGKLAWTTACLQESQRYFSSVWIIAREAVDDDII-DGHRIRRGTTVVIP 365 Query: 1263 SYSMGRMEGVWGKDCMEFSPERWI---TDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQ 1433 + + + W D F P R++ TD +P ++ F G R C+G+ A + Sbjct: 366 IHHIHH-DPRWWPDPDRFDPGRFLRCPTD------RPRCAYLPFGGGRRICIGQSFALME 418 Query: 1434 MKTVAATVLWNFTLETVPGHTVKPKLSIVLHMKNGLAVTVKRR 1562 M +AA + +FT + PG+ V+ + ++ L K+G+ V +RR Sbjct: 419 MVLMAAIMSQHFTFDLAPGYHVELEATLTLRPKHGVHVIGRRR 461
>P59954:CP132_MYCBO Putative cytochrome P450 132 - Mycobacterium bovis| Length = 461 Score = 127 bits (318), Expect = 2e-28 Identities = 116/463 (25%), Positives = 202/463 (43%), Gaps = 14/463 (3%) Frame = +3 Query: 216 DWATGVLATTRYNFAAHMGLTGVRFFLTCDPSNVRHIFISNSINYPRGEEYADIFDVLGD 395 D G L R + G RF P V H+ + Y + +EY I G Sbjct: 32 DAGDGFLGRLRGSDITRFRCAGRRFVSISHPDYVDHVLHEARLKYVKSDEYGPIRATAGL 91 Query: 396 GIFNADGESWRRQRAKSQLIMASPRFRSFSARCTRDKVERSLLPFLAHAADV--GARCDL 569 + +G+SW R R +F+ R R V + P A + GA+ D+ Sbjct: 92 NLLTDEGDSWARHRGALN--------STFARRHLRGLVGLMIDPIADVTAALVPGAQFDM 143 Query: 570 HDVLLRLMFDMTCNLVFGVDPGCLQIGLPSLP---LARAMDDVLETLFLRHVIPPACWRL 740 H ++ + N +F D G L + L L RA + LE L L ++P + Sbjct: 144 HQSMVETTLRVVANALFSQDFGPLVQSMHDLATRGLRRA--EKLERLGLWGLMPRTVYDT 201 Query: 741 MYRYGFG------PEKKMAVARRIIDRFAADTIVKRRYSGHKLRGEGITESSDILSFFIC 902 + + P ++M +DR A ++++ RR + T S+D+L+ + Sbjct: 202 LIWCIYSGVHLPPPLREMQEITLTLDR-AINSVIDRRLAEP-------TNSADLLNVLL- 252 Query: 903 NDDASEHSDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKK 1082 + D + +RD A+ + AG +TT +SWF+YL+ NP+ +L EL + ++ Sbjct: 253 SADGGIWPRQRVRDEALTFMLAGHETTANAMSWFWYLMALNPQARDHMLTELDDVLGMRR 312 Query: 1083 VDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVY 1262 A +L + + A L E R + SV I + A +D++ GH I+ G +++ Sbjct: 313 PT------ADDLGKLAWTTACLQESQRYFSSVWIIAREAVDDDII-DGHRIRRGTTVVIP 365 Query: 1263 SYSMGRMEGVWGKDCMEFSPERWI---TDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQ 1433 + + + W D F P R++ TD +P ++ F G R C+G+ A + Sbjct: 366 IHHIHH-DPRWWPDPDRFDPGRFLRCPTD------RPRCAYLPFGGGRRICIGQSFALME 418 Query: 1434 MKTVAATVLWNFTLETVPGHTVKPKLSIVLHMKNGLAVTVKRR 1562 M +AA + +FT + PG+ V+ + ++ L K+G+ V +RR Sbjct: 419 MVLMAAIMSQHFTFDLAPGYHVELEATLTLRPKHGVHVIGRRR 461
>Q12573:CP52W_CANAP Cytochrome P450 52E2 - Candida apicola (Yeast)| Length = 519 Score = 126 bits (316), Expect = 3e-28 Identities = 113/430 (26%), Positives = 177/430 (41%), Gaps = 26/430 (6%) Frame = +3 Query: 261 AHMGLTGVRFFLTCDPSNVRHIFISNSINYPRGEEYADIFDVLGDGIFNADGESWRRQRA 440 A + G + T +P N++ + ++ +Y G Y ++ +LG+GIF G+ W+ RA Sbjct: 84 AFQSVAGQLWIGTIEPENIKTMLATSFKDYSLGFRYNAMYGLLGNGIFTLSGDGWKNSRA 143 Query: 441 KSQLIMASPRFRSFSARCTRDKVERSLLPFLAHAADVGARCDLHDVLLRLMFDMTCNLVF 620 + P+F S + + + + + G D + L D +F Sbjct: 144 -----LLRPQF-SREQVSHLESMRTHINMMINNHFKGGQVVDAQVLYHNLTIDTATEFLF 197 Query: 621 G-----VDPGCLQIGLP-------SLPLARAMDDVLETLFLRHVIPPACWRLMYRYGFGP 764 G +DP Q GLP A A LE L +R V+ A W L++ F Sbjct: 198 GESTNTLDPALAQQGLPGPKGLVTGEQFAEAFTSALELLSVR-VMAGAAWFLVWTPKFW- 255 Query: 765 EKKMAVARRIIDRFAADTIVKRRYSGHKLRGEGITESSDILSFFICNDDASEHSD-EFLR 941 + V ID F +K + + D + + E SD +R Sbjct: 256 -RSCKVCHNFIDYFV-----------YKALATPMEKGQDADRYVFIRELTKETSDPRVIR 303 Query: 942 DTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDA---- 1109 D A+N+L AGRDTT A+LS+ Y L P V DEL + D DA Sbjct: 304 DQALNILLAGRDTTAALLSFTTYYLGAYPEV----YDELREAV----IADFGSADAEPPT 355 Query: 1110 -SELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHE--------IKAGDKILVY 1262 +L L + E LRL+P+VP+ + A + P+G + G K+ Sbjct: 356 FEQLKQCKVLQNVIREVLRLHPNVPLNFREAIADTTFPTGGGPNGDQPIFVPKGQKVFYA 415 Query: 1263 SYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKT 1442 +Y M R G+WG D F P+RW ++ + + +I FN GPR CLG++ A T+ Sbjct: 416 TYVMQRNAGIWGPDSTSFRPDRW--NEPREALASGWDYIPFNGGPRICLGQQFALTEASY 473 Query: 1443 VAATVLWNFT 1472 + F+ Sbjct: 474 TLVRICQEFS 483
>Q6ZWL3:CP4V2_HUMAN Cytochrome P450 4V2 - Homo sapiens (Human)| Length = 525 Score = 125 bits (314), Expect = 6e-28 Identities = 118/505 (23%), Positives = 214/505 (42%), Gaps = 19/505 (3%) Frame = +3 Query: 108 SYYRRLQSKKTTKEEPTEWPLLGHLLSTLANVSNLHDWATGVLATTRYNFAAHMGLTGVR 287 SY R+ Q + +PL+GH L + R+ + + V Sbjct: 39 SYARKWQQMRPIPTVARAYPLVGHALLMKPDGREFFQQIIEYTEEYRHMPLLKLWVGPVP 98 Query: 288 FFLTCDPSNVRHIFISNSINYPRGEEYADIFDVLGDGIFNADGESWRRQRAKSQLIMASP 467 + NV + +++S + Y + LG G+ + G WR +R M +P Sbjct: 99 MVALYNAENVE-VILTSSKQIDKSSMYKFLEPWLGLGLLTSTGNKWRSRRK-----MLTP 152 Query: 468 RFRSFSARCTRDKVERS----LLPFLAHAADVGARCDLHDVLLRLMFDMTCNLVFGVDPG 635 F D + + H C + L L D+ C G + G Sbjct: 153 TFHFTILEDFLDIMNEQANILVKKLEKHINQEAFNCFFYITLCAL--DIICETAMGKNIG 210 Query: 636 CLQIGLPSLPLARAMDDVLETLFLRHVIPPA---CWRLMYRYGFGPEKKMAVARRIIDRF 806 RA+ + E +F R +P W LM++ G+ +K + +I+ F Sbjct: 211 AQSND--DSEYVRAVYRMSEMIFRRIKMPWLWLDLWYLMFKEGWEHKKSL----KILHTF 264 Query: 807 AADTIVKRRY---SGHKLRGEGITESSDI--------LSFFICNDDASEHSDEFLRDTAV 953 I +R + RG+G + L + +D+ + S E +R+ Sbjct: 265 TNSVIAERANEMNANEDCRGDGRGSAPSKNKRRAFLDLLLSVTDDEGNRLSHEDIREEVD 324 Query: 954 NLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVY 1133 +F G DTT A ++W YLL NP V++ + EL + + V +L + Y Sbjct: 325 TFMFEGHDTTAAAINWSLYLLGSNPEVQKKVDHELDDVFGKSDRPATV----EDLKKLRY 380 Query: 1134 LHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCME 1313 L + E LRL+PSVP+ ++ + D +G+ + G + ++ Y++ R + + + E Sbjct: 381 LECVIKETLRLFPSVPLFARSVS-EDCEVAGYRVLKGTEAVIIPYALHR-DPRYFPNPEE 438 Query: 1314 FSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLET-VPG 1490 F PER+ ++ + RH PY ++ F+AGPR C+G++ A + KT+ + +L +F +E+ Sbjct: 439 FQPERFFPENAQGRH--PYAYVPFSAGPRNCIGQKFAVMEEKTILSCILRHFWIESNQKR 496 Query: 1491 HTVKPKLSIVLHMKNGLAVTVKRRN 1565 + + ++L NG+ + +KRRN Sbjct: 497 EELGLEGQLILRPSNGIWIKLKRRN 521
>Q5RCN6:CP4V2_PONPY Cytochrome P450 4V2 - Pongo pygmaeus (Orangutan)| Length = 525 Score = 122 bits (305), Expect = 6e-27 Identities = 118/505 (23%), Positives = 214/505 (42%), Gaps = 19/505 (3%) Frame = +3 Query: 108 SYYRRLQSKKTTKEEPTEWPLLGHLLSTLANVSNLHDWATGVLATTRYNFAAHMGLTGVR 287 SY R+ Q + +PL+GH L + R+ + + V Sbjct: 39 SYARKWQQMRPIPTVARAYPLVGHALLMKRDGREFFQQIIEYTEEYRHMPLLKLWVGPVP 98 Query: 288 FFLTCDPSNVRHIFISNSINYPRGEEYADIFDVLGDGIFNADGESWRRQRAKSQLIMASP 467 + NV + +++S + Y + LG G+ + G WR +R M +P Sbjct: 99 MVALYNAENVE-VILTSSRQIDKSSMYKFLEPWLGLGLLTSTGNKWRSRRK-----MLTP 152 Query: 468 RFRSFSARCTRDKVERS----LLPFLAHAADVGARCDLHDVLLRLMFDMTCNLVFGVDPG 635 F D + + H C + L L D+ C G + G Sbjct: 153 TFHFTILEDFLDIMNEQANILVKKLEKHVNQEAFNCFFYITLCAL--DIICETAMGKNIG 210 Query: 636 CLQIGLPSLPLARAMDDVLETLFLRHVIPPA---CWRLMYRYGFGPEKKMAVARRIIDRF 806 RA+ + + +F R +P W LM++ G+ EK + +I+ F Sbjct: 211 AQSND--DSEYVRAVYRMSQMIFQRIKMPWLWLDLWYLMFKEGWEHEKGL----KILHTF 264 Query: 807 AADTIVKRRYSGHKLR-----GEGITESSDILSFF------ICNDDASEHSDEFLRDTAV 953 + I +R + G G S + F + +D+ + S E +R+ Sbjct: 265 TNNVIAERANEMNADEDCRGVGRGSAPSKNKRRAFLDLLLSVTDDEGNRLSHEDIREEVD 324 Query: 954 NLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVY 1133 +F G DTT A ++W YLL NP V+Q + EL + + V +L + Y Sbjct: 325 TFMFEGHDTTAAAINWSLYLLGCNPEVQQKVDHELDDVFGKSDRPATV----EDLKKLRY 380 Query: 1134 LHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCME 1313 L + E LRL+PSVP+ ++ + D +G+ + G + ++ Y++ R + + + E Sbjct: 381 LECVIKETLRLFPSVPLFARSVS-EDCEVAGYRVLKGTEAVIIPYALHR-DPRYFPNPEE 438 Query: 1314 FSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLET-VPG 1490 F PER+ ++ + RH PY ++ F+AGPR C+G++ A + KT+ + +L +F +E+ Sbjct: 439 FQPERFFPENAQGRH--PYAYVPFSAGPRNCIGQKFAVMEEKTILSCILRHFWIESNQKR 496 Query: 1491 HTVKPKLSIVLHMKNGLAVTVKRRN 1565 + + ++L NG+ + +KRR+ Sbjct: 497 EELGLEGQLILRPSNGIWIKLKRRD 521
>Q12586:CP52I_CANMA Cytochrome P450 52A9 - Candida maltosa (Yeast)| Length = 521 Score = 121 bits (304), Expect = 8e-27 Identities = 108/440 (24%), Positives = 177/440 (40%), Gaps = 35/440 (7%) Frame = +3 Query: 294 LTCDPSNVRHIFISNSINYPRGEEYADIFDVLGDGIFNADGESWRRQRAK---------- 443 +T DP N++ I + ++ G+ +LG GIF DGE W+ RA Sbjct: 100 VTKDPENIKAILATQFEDFSLGKRLDFFKPLLGYGIFTLDGEGWKHSRAMLRPQFAREQV 159 Query: 444 SQLIMASPRFRSFSARCTRDKVERSLLPFLAHAADVGARCDLHDVLLRLMFDMTCNLVFG 623 + + P F+S ++K G D+ ++ R D +FG Sbjct: 160 GHVKLIEPHFQSLKKHIIKNK---------------GQFFDIQELFFRFTVDSATEFLFG 204 Query: 624 VDPGCLQ---IGLPSLPL--------ARAMDDVLETLFLRHVIPPACWRLMYRYGFGPEK 770 L+ IG A A + E L R ++ W + G +K Sbjct: 205 ESVESLKDESIGYDQQDFDFDGRKNFAEAFNKAQEYLGTRAILQLFYWLVN---GADFKK 261 Query: 771 KMAVARRIIDRFAADTIVK-----RRYSGHKLRGEGITESSDILSFFICNDDASEHSDEF 935 +A + D + + ++SG+ E + ++ D + Sbjct: 262 SVAEVHKFTDYYVQKALDATPEELEKHSGYIFLYELVQQTRD---------------PKV 306 Query: 936 LRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASE 1115 LRD ++N+L AGRDTT +LS+ + L NP V + +E+ + + + Sbjct: 307 LRDQSLNILLAGRDTTAGLLSFALFELARNPEVWSRLREEIGDKFGLDEDATIEGISFES 366 Query: 1116 LSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILV-------YSYSM 1274 L YL A + ECLR+YPSVP + AT + LP G D I + Y + Sbjct: 367 LKQCEYLKAVVNECLRMYPSVPRNFRIATKHTTLPRGGGPDGKDPIFIKKGAVVSYGINS 426 Query: 1275 GRMEGV-WGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAA 1451 ++ + +G D F+P+RW + K + + F+ FN GPR CLG++ A T+ V Sbjct: 427 THLDPMYYGPDARLFNPDRWSKPETK---KLGWAFLPFNGGPRICLGQQFALTEASYVLV 483 Query: 1452 TVLWNF-TLETVPGHTVKPK 1508 ++ NF LE P P+ Sbjct: 484 RMIQNFKELELTPNTVYPPR 503
>Q9HCS2:CP4FC_HUMAN Cytochrome P450 4F12 - Homo sapiens (Human)| Length = 524 Score = 121 bits (303), Expect = 1e-26 Identities = 130/504 (25%), Positives = 218/504 (43%), Gaps = 16/504 (3%) Frame = +3 Query: 102 FLSYYRRLQSKKTTKEEPTEWPLLGHLLSTLANVSNLHDWATGVLATTRYNFAAHMGLTG 281 F + RRLQ + W LG + T + + +T + AT F +G Sbjct: 41 FYNNCRRLQCFPQPPKRNWFWGHLGLITPTEEGLKD----STQMSATYSQGFTVWLGPI- 95 Query: 282 VRFFLTCDPSNVRHIFISNSINYPRGEEYADIFDV-LGDGIFNADGESWRRQRAKSQLIM 458 + F + C P +R I +++ P+ + LG+GI + G+ W R R +++ Sbjct: 96 IPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKPWLGEGILLSGGDKWSRHR---RMLT 152 Query: 459 ASPRFRSFSARCTR-DKVERSLLPFLAHAADVGA-RCDLHDVLLRLMFDMTCNLVFGVDP 632 + F + T +K +L H A G+ R D+ + + + D +F D Sbjct: 153 PAFHFNILKSYITIFNKSANIMLDKWQHLASEGSSRLDMFEHISLMTLDSLQKCIFSFDS 212 Query: 633 GCLQIGLPSLPLARAMD-DVLETLFLRHVIPPACWRLMYRYGFGPEKKMAVARRIIDRFA 809 C + PS +A ++ L +H++ + L Y G ++ A R++ F Sbjct: 213 HCQE--RPSEYIATILELSALVEKRSQHILQHMDF-LYYLSHDG--RRFHRACRLVHDFT 267 Query: 810 ADTIVKRRYSGHKLRGEGITE------SSDILSFFIC-----NDDASEHSDEFLRDTAVN 956 I +RR + L +GI + S L F ++D SDE +R A Sbjct: 268 DAVIRERRRT---LPTQGIDDFFKDKAKSKTLDFIDVLLLSKDEDGKALSDEDIRAEADT 324 Query: 957 LLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYL 1136 +F G DTT + LSW Y L +P ++ E+ + K D ++ +L+ + +L Sbjct: 325 FMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELL---KDRDPKEIEWDDLAQLPFL 381 Query: 1137 HAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEF 1316 + E LRL+P P + T + VLP G I G L+ + VW D + Sbjct: 382 TMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIPKGITCLIDIIGVHHNPTVW-PDPEVY 440 Query: 1317 SPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLETVPGHT 1496 P R+ ++ K R P FI F+AGPR C+G+ A +MK V A +L +F +P HT Sbjct: 441 DPFRFDPENSKGRS--PLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRF--LPDHT 496 Query: 1497 -VKPKLSIVLHMKNGLAVTVKRRN 1565 + KL +++ + GL + V+ N Sbjct: 497 EPRRKLELIMRAEGGLWLRVEPLN 520
>Q9HBI6:CP4FB_HUMAN Cytochrome P450 4F11 - Homo sapiens (Human)| Length = 524 Score = 120 bits (301), Expect = 2e-26 Identities = 123/510 (24%), Positives = 214/510 (41%), Gaps = 25/510 (4%) Frame = +3 Query: 102 FLSYYRRLQSKKTTKEEPTEWPLLGHLLSTLANVSNLHDWATGVLATTRYNFAAHMGLTG 281 F RRLQ ++ W G + T + L T ++ T F +G T Sbjct: 41 FYDNCRRLQCFPQPPKQNWFWGHQGLVTPTEEGMKTL----TQLVTTYPQGFKLWLGPT- 95 Query: 282 VRFFLTCDPSNVRHIFISNSINYPRGEE-YADIFDVLGDGIFNADGESWRRQRAKS---- 446 + C P +R I +++ P+ Y + LGDG+ + G+ W R R Sbjct: 96 FPLLILCHPDIIRPITSASAAVAPKDMIFYGFLKPWLGDGLLLSGGDKWSRHRRMLTPAF 155 Query: 447 QLIMASPRFRSF--SARCTRDKVERSLLPFLAHAADVGARCDLHDVLLRLMFDMTCNLVF 620 + P + F S DK +R A++ AR D+ + + + D VF Sbjct: 156 HFNILKPYMKIFNKSVNIMHDKWQRL-------ASEGSARLDMFEHISLMTLDSLQKCVF 208 Query: 621 GVDPGCLQ---------IGLPSLPLARAMDDVLETLFLRHVIPPACWRLMYRYGFGPEKK 773 + C + + L + R +L T FL ++ P ++ Sbjct: 209 SFESNCQEKPSEYIAAILELSAFVEKRNQQILLHTDFLYYLTPDG-------------QR 255 Query: 774 MAVARRIIDRFAADTIVKRRYS------GHKLRGEGITESSDILSFFICN--DDASEHSD 929 A ++ F I +RR + L+ + +++ D + + + +D E SD Sbjct: 256 FRRACHLVHDFTDAVIQERRRTLPTQGIDDFLKNKAKSKTLDFIDVLLLSKDEDGKELSD 315 Query: 930 EFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDA 1109 E +R A +F G DTT + LSW Y L ++P ++ E+ + K + + ++ Sbjct: 316 EDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQCRQEVQELL---KDREPIEIEW 372 Query: 1110 SELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEG 1289 +L+ + +L + E LRL+P VP+ + T + VLP G I G L+ + Sbjct: 373 DDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDFVLPDGRVIPKGIVCLINIIGIHYNPT 432 Query: 1290 VWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNF 1469 VW D + P R+ + ++ + P FI F+AGPR C+G+ A +MK V A L +F Sbjct: 433 VW-PDPEVYDPFRF--NQENIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALTLLHF 489 Query: 1470 TLETVPGHT-VKPKLSIVLHMKNGLAVTVK 1556 + +P HT + K ++L + GL + V+ Sbjct: 490 RI--LPTHTEPRRKPELILRAEGGLWLRVE 517
>Q9DBW0:CP4V3_MOUSE Cytochrome P450 4V3 - Mus musculus (Mouse)| Length = 525 Score = 119 bits (299), Expect = 3e-26 Identities = 115/515 (22%), Positives = 220/515 (42%), Gaps = 28/515 (5%) Frame = +3 Query: 105 LSYYRRLQSKKTTKEEPTEWPLLGHLLSTLANVSNLHDWATGVLATTRYNFAAHMGLTGV 284 +SY R+ Q ++ +PL+GH L N + R+ + + V Sbjct: 38 VSYARKWQQMRSIPSVARAYPLVGHALYMKPNNAEFFQQLIYYTEEFRHLPIIKLWIGPV 97 Query: 285 RFFLTCDPSNVRHIFISNSINYPRGEEYADIFDVLGDGIFNADGESWRRQRAKSQLIMAS 464 NV + +++S + Y + LG G+ + G WR +R M + Sbjct: 98 PLVALYKAENVE-VILTSSKQIDKSFLYKFLQPWLGLGLLTSTGSKWRTRRK-----MLT 151 Query: 465 PRFR-----------SFSARCTRDKVERSLLPFLAHAADVGARCDLHDVLLRLMFDMTCN 611 P F + A +K+E+ H C + L L D+ C Sbjct: 152 PTFHFTILENFLDVMNEQANILVNKLEK-------HVNQEAFNCFFYITLCAL--DIICE 202 Query: 612 LVFGVDPGCLQIGLPSLPLARAMDDVLETLFLRHVIPPA---CWRLMYRYGFGPEKKMAV 782 G + G R + + + ++ R +P W L+++ G ++ + Sbjct: 203 TAMGKNIGAQSNN--DSEYVRTVYRMSDMIYRRMKMPWLWFDLWYLVFKEGRDHKRGLKC 260 Query: 783 ARRIIDRFAADTIVKRR----YSGHKLRGEGITESSDILSFF------ICNDDASEHSDE 932 + A+ + +R+ ++G G G S + F + +++ + S E Sbjct: 261 LHTFTNNVIAERVKERKAEEDWTG---AGRGPIPSKNKRKAFLDLLLSVTDEEGNRLSQE 317 Query: 933 FLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDAS 1112 +R+ +F G DTT A ++W YLL NP V++ + EL + R + Sbjct: 318 DIREEVDTFMFEGHDTTAAAINWSLYLLGTNPEVQRKVDQELDEVFGRSHRP----VTLE 373 Query: 1113 ELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGV 1292 +L + YL + E LR++PSVP+ ++ + D G+++ G + ++ Y++ R + Sbjct: 374 DLKKLKYLDCVIKETLRVFPSVPLFARSLS-EDCEVGGYKVTKGTEAIIIPYALHR-DPR 431 Query: 1293 WGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFT 1472 + D EF PER+ ++ + RH PY ++ F+AGPR C+G++ A + KT+ A +L F Sbjct: 432 YFPDPEEFRPERFFPENSQGRH--PYAYVPFSAGPRNCIGQKFAVMEEKTILACILRQFW 489 Query: 1473 LETVPGHTVKPKL----SIVLHMKNGLAVTVKRRN 1565 +E+ + + +L ++L NG+ + +KRR+ Sbjct: 490 VES---NQKREELGLAGDLILRPNNGIWIKLKRRH 521
>P78329:CP4F2_HUMAN Cytochrome P450 4F2 - Homo sapiens (Human)| Length = 520 Score = 119 bits (298), Expect = 4e-26 Identities = 117/469 (24%), Positives = 204/469 (43%), Gaps = 25/469 (5%) Frame = +3 Query: 225 TGVLATTRYNFAAHMGLTGVRFFLTCDPSNVRHIFISNSINYPRGEEYADIFDV-LGDGI 401 T ++AT F MG L C P +R + +++ P+ + + + LGDG+ Sbjct: 78 TQLVATYPQGFKVWMGPISPLLSL-CHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGL 136 Query: 402 FNADGESWRRQRAKSQLIMASPRFRSFSARCTRDKVERSLLPFLAHA-----ADVGARC- 563 + G+ W R R M +P F F+ K+ + + HA A G+ C Sbjct: 137 LLSAGDKWSRHRR-----MLTPAFH-FNILKPYMKIFNESVNIM-HAKWQLLASEGSACL 189 Query: 564 DLHDVLLRLMFDMTCNLVFGVDPGCLQ---------IGLPSLPLARAMDDVLETLFLRHV 716 D+ + + + D VF D C + + L +L R + +L FL ++ Sbjct: 190 DMFEHISLMTLDSLQKCVFSFDSHCQEKPSEYIAAILELSALVSKRHHEILLHIDFLYYL 249 Query: 717 IPPACWRLMYRYGFGPEKKMAVARRIIDRFAADTIVKRRYS------GHKLRGEGITESS 878 P ++ A R++ F I +RR + L+ + +++ Sbjct: 250 TPDG-------------QRFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTL 296 Query: 879 DILSFFICN--DDASEHSDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILD 1052 D + + + +D + SDE +R A +F G DTT + LSW Y L ++P ++ Sbjct: 297 DFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQ 356 Query: 1053 ELAPIAARKKVDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHE 1232 E+ + ++ + ++ +L+ + +L + E LRL+P VP+ + T + VLP G Sbjct: 357 EVQELLKDREPKE---IEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRV 413 Query: 1233 IKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLG 1412 I G L+ + VW D + P R+ D ++ + P FI F+AGPR C+G Sbjct: 414 IPKGIICLISVFGTHHNPAVW-PDPEVYDPFRF--DPENIKERSPLAFIPFSAGPRNCIG 470 Query: 1413 KEVAFTQMKTVAATVLWNFTLETVPGHT-VKPKLSIVLHMKNGLAVTVK 1556 + A +MK V A L F +P HT + K +VL + GL + V+ Sbjct: 471 QTFAMAEMKVVLALTLLRF--RVLPDHTEPRRKPELVLRAEGGLWLRVE 517
>Q9V3S0:CP4G1_DROME Cytochrome P450 4g1 - Drosophila melanogaster (Fruit fly)| Length = 556 Score = 117 bits (292), Expect = 2e-25 Identities = 123/524 (23%), Positives = 214/524 (40%), Gaps = 50/524 (9%) Frame = +3 Query: 153 PTEWPLLGHLLSTLANVSNLHDWATGVLATTRYNFAAHMGLTGVRFFLTCDPSNVRHIFI 332 P E P+LG A +SN A G+ +Y L V +PS++ + + Sbjct: 60 PPELPILGQA-HVAAGLSNAEILAVGLGYLNKYGETMKAWLGNVLLVFLTNPSDIE-LIL 117 Query: 333 SNSINYPRGEEYADIFDVLGDGIFNADGESWRRQRAKSQLIMASPRFRSFSARCTRDKVE 512 S + + EEY GDG+ ++G WR R M +P F + Sbjct: 118 SGHQHLTKAEEYRYFKPWFGDGLLISNGHHWRHHRK-----MIAPTFHQ--------SIL 164 Query: 513 RSLLP-FLAHAADVGARC--------DLHDVLLRLMFDMTCNLVFGVDPGCLQIGLPSLP 665 +S +P F+ H+ V AR D+HD + + D+ + GV L G S Sbjct: 165 KSFVPTFVDHSKAVVARMGLEAGKSFDVHDYMSQTTVDILLSTAMGVKK--LPEGNKSFE 222 Query: 666 LARAMDDVLETLFLRHVIPPACWRLMYR----YGFGPEKKMAVARRIIDRFAADTIVKRR 833 A+A+ D+ + + R V +L+YR Y F ++ I +VK R Sbjct: 223 YAQAVVDMCDIIHKRQV------KLLYRLDSIYKFTKLREKGDRMMNIILGMTSKVVKDR 276 Query: 834 YSGHKLRGEGITES----------------SDILSFFICNDDAS---------------- 917 + I E D L ND + Sbjct: 277 KENFQEESRAIVEEISTPVASTPASKKEGLRDDLDDIDENDVGAKRRLALLDAMVEMAKN 336 Query: 918 ---EHSDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVD 1088 E +++ + D ++F G DTT A S+ ++ + ++ + E I + Sbjct: 337 PDIEWNEKDIMDEVNTIMFEGHDTTSAGSSFALCMMGIHKDIQAKVFAEQKAIFGDNMLR 396 Query: 1089 DMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSG-HEIKAGDKILVYS 1265 D D E M YL + E LRLYP VP+ + ++ L SG + + G ++V Sbjct: 397 DCTFADTME---MKYLERVILETLRLYPPVPLIARRLDYDLKLASGPYTVPKGTTVIVLQ 453 Query: 1266 YSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTV 1445 Y + R ++ +F P+ ++ + RH Y FI F+AGPR+C+G++ A ++K + Sbjct: 454 YCVHRRPDIYPNPT-KFDPDNFLPERMANRHY--YSFIPFSAGPRSCVGRKYAMLKLKVL 510 Query: 1446 AATVLWNFTLETVPGHT-VKPKLSIVLHMKNGLAVTVKRRNFFT 1574 +T++ N+ + + K + I+L ++NG V++++R + T Sbjct: 511 LSTIVRNYIVHSTDTEADFKLQADIILKLENGFNVSLEKRQYAT 554
>O46054:C4AE1_DROME Cytochrome P450 4ae1 - Drosophila melanogaster (Fruit fly)| Length = 496 Score = 116 bits (291), Expect = 3e-25 Identities = 106/431 (24%), Positives = 199/431 (46%), Gaps = 8/431 (1%) Frame = +3 Query: 294 LTCDPSNVRHI--FISNSINYPRGEEYADIFDVLGDGIFNADGESWRRQR---AKSQLIM 458 +T +P RHI + +G Y + LGDG+ + G+ W R + Sbjct: 83 VTAEP---RHIDALLQGQHQLKKGTMYFALRGWLGDGLLLSRGKEWHTMRKIITPTFHFS 139 Query: 459 ASPRFRSFSARCTRDKVERSLLPFLAHAADVGARCDLHDVLLRLMFDMTCNLVFGVDPGC 638 +F R + VER L L++ +V +++ ++ D+ GV+ Sbjct: 140 ILEQFVEVFDRQSSILVER--LRTLSYGNEV---VNIYPLVGLAALDIITETAMGVNVDA 194 Query: 639 LQIGLPSLPLARAMDDVLETLFLR-HVIPPACWRLMYRYGFGPEKKMAVARRIIDRFAAD 815 + + + ++L T F+R H++ P +RL + GF ++ + + F Sbjct: 195 QGADSEVVHAVKDLTNILATRFMRPHLLFPHLFRLCWPSGFRKQQAGVIC---LHEFTNG 251 Query: 816 TIV-KRRYSGHKLRGEGITESSDILSFFI-CNDDASEHSDEFLRDTAVNLLFAGRDTTGA 989 I +RR + + T+ +L + D +D+ +RD +F G DTT + Sbjct: 252 IIEQRRRLLAREANQDKPTKPHALLDTLLRATVDGQPLTDKQIRDEVNTFIFEGHDTTTS 311 Query: 990 VLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAALCECLRLY 1169 +S+ YLL + V+Q + +EL + +++ S+ +++ YL + E LRLY Sbjct: 312 AVSFCLYLLSRHEAVQQKLFEELRMHYGQDLFRGVIL---SDFATLPYLSCVVKESLRLY 368 Query: 1170 PSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWITDDGK 1349 P +P + + V+ G+ I G ++V + + R E ++ D + F PER + ++ Sbjct: 369 PPIPAVARCLEKDLVIDEGY-IPVGTNVVVLLWQLLRDEAIF-TDPLVFQPERHLGEEAP 426 Query: 1350 LRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLETVPGHTVKPKLSIVLHM 1529 PY +I F+AGPR C+G++ A +MKT+ V+ ++ L + G V+P + IVL Sbjct: 427 --RLSPYSYIPFSAGPRNCIGQKFALLEMKTMVTKVIRHYQLLPM-GADVEPSIKIVLRS 483 Query: 1530 KNGLAVTVKRR 1562 K+G+ V ++ R Sbjct: 484 KSGVNVGLRPR 494
>Q08477:CP4F3_HUMAN Cytochrome P450 4F3 - Homo sapiens (Human)| Length = 520 Score = 115 bits (288), Expect = 6e-25 Identities = 106/440 (24%), Positives = 189/440 (42%), Gaps = 23/440 (5%) Frame = +3 Query: 306 PSNVRHIFISNSINYPRGEE-YADIFDVLGDGIFNADGESWRRQRAKS----QLIMASPR 470 P+ ++ + + + P+ + Y+ + LGDG+ + GE W R R + P Sbjct: 104 PTYIKPVLFAPAAIVPKDKVFYSFLKPWLGDGLLLSAGEKWSRHRRMLTPAFHFNILKPY 163 Query: 471 FRSFSARCTRDKVERSLLPFLAHAADVGARCDLHDVLLRLMFDMTCNLVFGVDPGCLQ-- 644 + F+ + LL A++ AR D+ + + + D VF D C + Sbjct: 164 MKIFNESVNIMHAKWQLL-----ASEGSARLDMFEHISLMTLDSLQKCVFSFDSHCQEKP 218 Query: 645 -------IGLPSLPLARAMDDVLETLFLRHVIPPACWRLMYRYGFGPEKKMAVARRIIDR 803 + L +L R +L FL ++ P ++ A R++ Sbjct: 219 SEYIAAILELSALVTKRHQQILLYIDFLYYLTPDG-------------QRFRRACRLVHD 265 Query: 804 FAADTIVKRRYS------GHKLRGEGITESSDILSFFICN--DDASEHSDEFLRDTAVNL 959 F I +RR + L+ + +++ D + + + +D + SDE +R A Sbjct: 266 FTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTF 325 Query: 960 LFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLH 1139 +F G DTT + LSW Y L ++P ++ E+ + ++ + ++ +L+ + +L Sbjct: 326 MFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKE---IEWDDLAQLPFLT 382 Query: 1140 AALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFS 1319 + E LRL+P VP + T + VLP G I G L+ + VW D + Sbjct: 383 MCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKGIICLISVFGTHHNPAVW-PDPEVYD 441 Query: 1320 PERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLETVPGHT- 1496 P R+ D ++ + P FI F+AGPR C+G+ A +MK V L F +P HT Sbjct: 442 PFRF--DPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLGLTLLRF--RVLPDHTE 497 Query: 1497 VKPKLSIVLHMKNGLAVTVK 1556 + K +VL + GL + V+ Sbjct: 498 PRRKPELVLRAEGGLWLRVE 517
>Q27519:C13A7_CAEEL Putative cytochrome P450 CYP13A7 - Caenorhabditis elegans| Length = 518 Score = 114 bits (284), Expect = 2e-24 Identities = 136/523 (26%), Positives = 209/523 (39%), Gaps = 46/523 (8%) Frame = +3 Query: 81 FVGLVCCFLSYYRRLQSKKTTK--EEPTEWPLLGHLLSTLANVSNLHDWATGVLATTRYN 254 FVG++ SYY + S K + P P LG ++ N N G L + + Sbjct: 12 FVGII----SYYLWIWSFWIRKGVKGPRGLPFLG-VIHKFTNYEN-----PGALKFSEWT 61 Query: 255 --FAAHMGLT-GV-RFFLTCDPSNVRHIFISNSINYPRGEEYADIFDVLGDGIFN----- 407 + G+T GV + + DP V +F+ N+ + A + GD N Sbjct: 62 KKYGPVYGITEGVEKTLVISDPEFVHEVFVKQFDNFYGRKLTA----IQGDPNKNKRVPL 117 Query: 408 --ADGESWRRQRAKSQLIMASPRFRSFSARCTRDKVERS---LLPFLAHAADVGARCDLH 572 A G W+R R +ASP F + S R VE S L+ L A+ G D+ Sbjct: 118 VAAQGHRWKRLRT-----LASPTFSNKSLRKIMGTVEESVTELVRSLEKASAEGKTLDML 172 Query: 573 DVLLRLMFDMTCNLVFGVDPGCLQIGLPSLPLARAMDDVLETLF---------LRHVIPP 725 + D+ + G + SL M D ++T+F + + P Sbjct: 173 EYYQEFTMDIIGKMAMGQEK--------SLMFRNPMLDKVKTIFKEGRNNVFMISGIFPF 224 Query: 726 ACWRLMYRYGFGPEKKMAVARRIIDRFAADTIVKRRYSGHKLRGEGITESSDILSFFICN 905 L + P +MA + I A + +++R + K E E D + F+ Sbjct: 225 VGIALRNIFAKFPSLQMATDIQSILEKALNKRLEQREADEKAGIEPSGEPQDFIDLFLDA 284 Query: 906 DDA-----SEHSDEFLRDTAVNL----------------LFAGRDTTGAVLSWFFYLLCE 1022 E +F + + + L AG DTT LS+ YLL Sbjct: 285 RSTVDFFEGEAEQDFAKSEVLKVDKHLTFDEIIGQLFVFLLAGYDTTALSLSYSSYLLAT 344 Query: 1023 NPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAAT 1202 +P +++ + +E+ R+ D V D +LS + YL + E LRLYP + H Sbjct: 345 HPEIQKKLQEEVD----RECPDPEVTFD--QLSKLKYLECVVKEALRLYPLASLVHNRKC 398 Query: 1203 HNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIA 1382 G EI+AG I V ++S+ VWG D EF PERW + D + Y + Sbjct: 399 LKTTNVLGMEIEAGTNINVDTWSLHHDPKVWGDDVNEFKPERWESGDELFFAKGGY--LP 456 Query: 1383 FNAGPRTCLGKEVAFTQMKTVAATVLWNFTLETVPGHTVKPKL 1511 F GPR C+G +A +MK + +L N+T ET P + KL Sbjct: 457 FGMGPRICIGMRLAMMEMKMLLTNILKNYTFETTPETVIPLKL 499
>P15129:CP4B1_RAT Cytochrome P450 4B1 - Rattus norvegicus (Rat)| Length = 511 Score = 112 bits (279), Expect = 7e-24 Identities = 120/493 (24%), Positives = 198/493 (40%), Gaps = 25/493 (5%) Frame = +3 Query: 153 PTEWPLLGHLLST--LANVSNLHDWATGVLATTRYNFAAHMGLTGVRFFLTCDPSNVRHI 326 PT W L GH L L ++ + WA F +G + +P + + Sbjct: 50 PTHW-LFGHALEIQKLGSLDKVVSWAQQFPHAHPLWFGQFVGFLNIY-----EPDYAKAV 103 Query: 327 FISNSINYPRGE-EYADIFDV----LGDGIFNADGESWRRQRAKSQLIMASPRFR----- 476 Y RG+ + AD++D +G G+ DG W + R + +P F Sbjct: 104 -------YSRGDPKAADVYDFFLQWIGKGLLVLDGPKWFQHRK-----LLTPGFHYDVLK 151 Query: 477 ------SFSARCTRDKVERSLLPFLAHAADVGARCDLHDVLLRLMFDMTCNLVFGVDPGC 638 + S R DK E+ + CD+ + L + T FG G Sbjct: 152 PYVAIFAESTRMMLDKWEKKA----SENKSFDIFCDVGHMALDTLMKCT----FG--KGD 201 Query: 639 LQIGLPSLPLARAMDDVLETLFLRHVIPPACWRLMYRYGFGPEKKMAVARRIIDRFAADT 818 +G A+ D+ TL ++ I + + Y P + + I D Sbjct: 202 SGLGHRDNSYYLAVSDL--TLLMQQRIDSFQYHNDFIYWLTPHGRRFLRACKIAHDHTDE 259 Query: 819 IVKRRYSG-------HKLRGEGITESSDILSFFICNDDASEHSDEFLRDTAVNLLFAGRD 977 ++++R + K++ + DIL + ++ + SD LR +F G D Sbjct: 260 VIRQRKAALQDEKERKKIQQRRHLDFLDIL-LGVRDESGIKLSDAELRAEVDTFMFEGHD 318 Query: 978 TTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAALCEC 1157 TT + +SWF Y + P +Q+ +E+ I + D +L+ M YL + EC Sbjct: 319 TTTSGISWFLYCMALYPEHQQLCREEVRGI-----LGDQDSFQWDDLAKMTYLTMCMKEC 373 Query: 1158 LRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWIT 1337 RLYP VP ++ G + AG I ++ Y++ R VW D F P R+ Sbjct: 374 FRLYPPVPQVYRQLNKPVTFVDGRSLPAGSLISLHIYALHRNSTVW-PDPEVFDPLRFSP 432 Query: 1338 DDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLETVPGHTVKPKLSI 1517 ++ RH P+ F+ F+AGPR C+G++ A +MK V A L F P + Sbjct: 433 ENAAGRH--PFAFMPFSAGPRNCIGQQFAMNEMKVVTALCLLRFEFSLDPSKMPIKVPQL 490 Query: 1518 VLHMKNGLAVTVK 1556 +L KNG+ + +K Sbjct: 491 ILRSKNGIHLYLK 503
>Q9V7G5:C4AA1_DROME Probable cytochrome P450 4aa1 - Drosophila melanogaster (Fruit fly)| Length = 514 Score = 112 bits (279), Expect = 7e-24 Identities = 114/442 (25%), Positives = 195/442 (44%), Gaps = 16/442 (3%) Frame = +3 Query: 288 FFLTCDPSNVRHIFISNSINYPRGEEYADIFDVLGDGIFNADGESWRRQRAKSQLIMASP 467 FF +P +++ + +S+ + + Y + + LGDG+ + G W R Q Sbjct: 97 FFAVLEPEDLQ-VILSSKKHTNKVFFYRLMHNFLGDGLITSSGSKWSNHRRLIQPAFHHN 155 Query: 468 RFRSFSARCTRDKVERSLLPFLAHAADVGARCDLHDVLLRLMFDMTCNLVFGVDPGCLQI 647 F T +SL L A VG ++ + + D+ V GV Sbjct: 156 LLEKFID--TFVDASQSLYENL-DAEAVGTEINIAKYVNNCVLDILNEAVLGV------- 205 Query: 648 GLPSLPLARAMDDV--LETLFLRH--VIPPAC----WRLM---YRYGFGPEKKMAVARRI 794 P+ + DV +E R ++ PA W L+ Y + ++ +R+ Sbjct: 206 -----PIKKRGQDVAMMEDSPFRQGKIMMPARFTQPWLLLDGIYHWTKMANDELNQKKRL 260 Query: 795 IDRFAADTIVKRRYSGHKLRGEGITESSDILSFFICNDDASEHSDEFLRDTAVN----LL 962 D F I +RR + G +E +L I + SE + +F + VN + Sbjct: 261 ND-FTRKMIQRRRQIQNNNNGN--SERKCLLDHMI---EISESNRDFTEEDIVNEACTFM 314 Query: 963 FAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHA 1142 AG+D+ GA +++ +LL +NP + + ELA I D ++L M Y+ Sbjct: 315 LAGQDSVGAAVAFTLFLLTQNPECQDRCVLELATIFE----DSNRAPTMTDLHEMRYMEM 370 Query: 1143 ALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSP 1322 + E LRLYPSVP+ + +V + H + AG + + Y+ R+ ++ D +F P Sbjct: 371 CIKEALRLYPSVPLIARKLGE-EVRLAKHTLPAGSNVFICPYATHRLAHIY-PDPEKFQP 428 Query: 1323 ERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLETVPGH-TV 1499 ER+ ++ + RH PY F+ F+AGPR C+G A ++KT+ + +L ++ L V G T+ Sbjct: 429 ERFSPENSENRH--PYAFLPFSAGPRYCIGNRFAIMEIKTIVSRLLRSYQLLPVTGKTTI 486 Query: 1500 KPKLSIVLHMKNGLAVTVKRRN 1565 I L GL V +K R+ Sbjct: 487 AATFRITLRASGGLWVRLKERD 508
>Q12585:CP52T_CANMA Cytochrome P450 52D1 - Candida maltosa (Yeast)| Length = 505 Score = 111 bits (277), Expect = 1e-23 Identities = 112/441 (25%), Positives = 181/441 (41%), Gaps = 12/441 (2%) Frame = +3 Query: 279 GVRFFLTCDPSNVRHIFISNSINYPRGEEYADIFDVLGDGIFNADGESWRRQRAKSQLIM 458 G+ LT DP N++ + + G Y +LG+GIF +DGE W+ R IM Sbjct: 85 GIPIILTRDPVNIKAMLAVQFDEFSLGLRYNQFEPLLGNGIFTSDGEPWKHSR-----IM 139 Query: 459 ASPRF-RSFSARCTRDKVERSLLPFLAHAADVGARCDLHDVLLRLMFDMTCNLVFGVDPG 635 P+F +S + R + +LL A D+ + R D +FG Sbjct: 140 LRPQFIKSQVSHVNRLEPHFNLLQKNI-TAQTDNYFDIQTLFFRFTLDTATEFLFGQSVH 198 Query: 636 CLQIGLPSLPLARAMDDVLETLFLRHVIPPACWRLMYRYGFGPEKKMAVARRIIDRFAAD 815 L G SL A L R L Y K +++ F+ Sbjct: 199 SLNDGENSLQFLEAFTKSQAILATRA-------NLHELYFLADGIKFRQYNKMVQDFSQR 251 Query: 816 TIVKRRYSGHKLRGEGITESSDILSFFICNDDAS-EHSDEFLRDTAVNLLFAGRDTTGAV 992 + K+ +E + +F + + + LRD +N+L AGRDTT ++ Sbjct: 252 CV-------DKVLNMSNSEIDKLDRYFFLYEMVKITRNPQVLRDQCLNILLAGRDTTASL 304 Query: 993 LSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAALCECLRLYP 1172 LS+ F+ L N + + E+ + +++ D + + YL A L E LRLYP Sbjct: 305 LSFAFFELALNEPIWIKLRTEVLHVFQTSL--ELITFDLLK-TKCPYLQAILHETLRLYP 361 Query: 1173 SVPITHKAATHNDVLPSGHE--------IKAGDKILVYSYSMGRMEGVWGKDCMEFSPER 1328 SVP + + N LP G IK G + + + E + KD + F PER Sbjct: 362 SVPRNARFSKKNTTLPHGGGVDGMSPILIKKGQPVAYFICATHVDEKFYTKDALIFRPER 421 Query: 1329 WITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLETVPGHTVK-- 1502 W ++ ++ + ++ FN GPR CLG++ A T+ V + +T ++ ++ + Sbjct: 422 W-CEEPLIKKNLAWSYLPFNGGPRICLGQQFALTEASYVLTRLAQCYTKISLQPNSFEYP 480 Query: 1503 PKLSIVLHMKNGLAVTVKRRN 1565 PK + L M V VK N Sbjct: 481 PKKQVHLTMSLLDGVHVKISN 501
>O18596:C4D10_DROMT Cytochrome P450 4d10 - Drosophila mettleri (Fruit fly)| Length = 513 Score = 111 bits (277), Expect = 1e-23 Identities = 113/443 (25%), Positives = 199/443 (44%), Gaps = 30/443 (6%) Frame = +3 Query: 324 IFISNSINYPRGEEYADIFDVLGDGIFNADGESWRRQRAKSQLIMASPRFRSFSARCTR- 500 + + +S + EY+ + L DG+ + G W R+R ++I + FR + Sbjct: 101 VVLGSSQLLDKAVEYSFLRGWLNDGLLLSGGRKWHRRR---KIITPAFHFRILESYDEIF 157 Query: 501 DKVERSLL----PFLAHAADVGARCDLHDVLLRLMFDMTCNLVFGVDPGCLQ-------- 644 D+ R L+ L H+ D+G HDV L D+ C GV Sbjct: 158 DRQTRLLIHKWQQTLGHSFDLG-----HDVHL-FTLDVICETAMGVSTNAQTNADSDYVR 211 Query: 645 -IGLPSLPLARAMDDVLETLFLRHVIPPACWRLMYRYGFGPEKKMAVARRIIDRFAADTI 821 + S L + M ++ L +++ P W E++ A ++ +F I Sbjct: 212 AVKTISTVLHKRMFNIFYRFDLTYMLTPLAWA---------ERR---ALNVLHKFTEKII 259 Query: 822 VKRRYSGHKLRGEGITESSD-----------ILSFFI-CNDDASEHSDEFLRDTAVNLLF 965 V+RR LRG G+T+++D L + N D ++ +R+ +F Sbjct: 260 VQRREE--LLRG-GVTQTTDGADVGAKSKMVFLDILLQSNIDDKPLTNLDIREEVDTFMF 316 Query: 966 AGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAA 1145 G DTT + +++FFY + P ++ ++E+ + K + V D L+++ Y+ Sbjct: 317 EGHDTTSSGITFFFYNIALYPECQRKCVEEIVSVLG-KDTETPVTYDL--LNNLNYMDLC 373 Query: 1146 LCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPE 1325 + E LR+YPSVP+ + + +G I AG I + +GR E + + F PE Sbjct: 374 IKETLRMYPSVPLLGRKVLQECEI-NGKIIPAGTNIGISPLFLGRSEDI-SSEPNTFKPE 431 Query: 1326 RW--ITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLETVPGHTV 1499 R+ +T KL P+ +I F+AGPR C+G++ A ++K +AA VL ++ +E V Sbjct: 432 RFDVVTSAEKLN---PHAYIPFSAGPRNCIGQKFAMLEIKAIAANVLRHYEIEFVGNAEE 488 Query: 1500 KPKL--SIVLHMKNGLAVTVKRR 1562 P L ++L K+ L +K+R Sbjct: 489 SPVLIAELILRTKDPLMFKLKKR 511
>Q6NT55:CP4FN_HUMAN Cytochrome P450 4F22 - Homo sapiens (Human)| Length = 531 Score = 110 bits (275), Expect = 2e-23 Identities = 113/501 (22%), Positives = 208/501 (41%), Gaps = 18/501 (3%) Frame = +3 Query: 108 SYYRRLQSKKTTKEEPTEWPLLGHLLSTLANVSNLHDWATGVLATTRYNFAAHMGLTGVR 287 S+Y + + + P LLGHL L N + L D VL + MG + Sbjct: 48 SFYITCRRLRCFPQPPRRNWLLGHLGMYLPNEAGLQD-EKKVLDNMHHVLLVWMGPV-LP 105 Query: 288 FFLTCDPSNVRHIFISNSINYPRGEE-YADIFDVLGDGIFNADGESWRRQRAKSQLIMAS 464 + P ++ + +++ P+ + Y + LGDG+ + G+ W R R + + Sbjct: 106 LLVLVHPDYIKPLLGASAAIAPKDDLFYGFLKPWLGDGLLLSKGDKWSRHRR-----LLT 160 Query: 465 PRFRSFSARCTRDKVERSLLPFL----AHAADVGA-RCDLHDVLLRLMFDMTCNLVFGVD 629 P F F K+ + H A+ A D+ + + + D VF + Sbjct: 161 PAFH-FDILKPYMKIFNQSADIMHAKWRHLAEGSAVSLDMFEHISLMTLDSLQKCVFSYN 219 Query: 630 PGCLQIGLPSLPLARAMDDVLETLFLRHVIPPACWRLMYRYGF-----GPEKKMAVARRI 794 C + + D + + L + +RL + F ++ A + Sbjct: 220 SNCQE---------KMSDYISAIIELSALSVRRQYRLHHYLDFIYYRSADGRRFRQACDM 270 Query: 795 IDRFAADTIVKRRYSGHKLRGEGITESS-----DILSFFIC--NDDASEHSDEFLRDTAV 953 + F + I +RR + + E ++ D + + ++D E SDE +R A Sbjct: 271 VHHFTTEVIQERRRALRQQGAEAWLKAKQGKTLDFIDVLLLARDEDGKELSDEDIRAEAD 330 Query: 954 NLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVY 1133 +F G DTT + +SW + L + P ++ +E+ + +++++ L+ +L+ + + Sbjct: 331 TFMFEGHDTTSSGISWMLFNLAKYPEYQEKCREEIQEVMKGRELEE---LEWDDLTQLPF 387 Query: 1134 LHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCME 1313 + E LR YP V + + T + LP G I G LV Y VW D Sbjct: 388 TTMCIKESLRQYPPVTLVSRQCTEDIKLPDGRIIPKGIICLVSIYGTHHNPTVW-PDSKV 446 Query: 1314 FSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLETVPGH 1493 ++P R+ D+ + R P ++ F+AGPR C+G+ A +++ V A L F L Sbjct: 447 YNPYRFDPDNPQQRS--PLAYVPFSAGPRNCIGQSFAMAELRVVVALTLLRFRLSVDRTR 504 Query: 1494 TVKPKLSIVLHMKNGLAVTVK 1556 V+ K ++L +NGL + V+ Sbjct: 505 KVRRKPELILRTENGLWLKVE 525
>P15128:CP4B1_RABIT Cytochrome P450 4B1 - Oryctolagus cuniculus (Rabbit)| Length = 506 Score = 110 bits (275), Expect = 2e-23 Identities = 69/211 (32%), Positives = 101/211 (47%) Frame = +3 Query: 924 SDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVL 1103 SD LR +F G DTT + +SWF Y + P +Q +E+ R+ + D Sbjct: 296 SDTDLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQQRCREEV-----REILGDQDSF 350 Query: 1104 DASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRM 1283 +L+ M YL + EC RLYP VP ++ + G + AG I ++ Y++ R Sbjct: 351 QWEDLAKMTYLTMCMKECFRLYPPVPQVYRQLSKPVSFVDGRSLPAGSLISLHIYALHRN 410 Query: 1284 EGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLW 1463 VW D F P R+ ++ RH PY FI F+AGPR C+G++ A +MK V A L Sbjct: 411 SDVW-PDPEVFDPLRFSPENSSGRH--PYAFIPFSAGPRNCIGQQFAMNEMKVVTALCLL 467 Query: 1464 NFTLETVPGHTVKPKLSIVLHMKNGLAVTVK 1556 F P +VL KNG+ + +K Sbjct: 468 RFEFSVDPLRLPIKLPQLVLRSKNGIHLYLK 498
>Q9EP75:CP4FE_MOUSE Cytochrome P450 4F14 - Mus musculus (Mouse)| Length = 524 Score = 110 bits (274), Expect = 3e-23 Identities = 93/378 (24%), Positives = 164/378 (43%), Gaps = 15/378 (3%) Frame = +3 Query: 387 LGDGIFNADGESWRRQRAKSQLIMASPRFRSFS-----ARCTRDKVERSLLPFLAHAADV 551 LGDG+ + G+ W R R M +P F F+ + D + +D Sbjct: 132 LGDGLLVSAGDKWSRHRR-----MLTPAFH-FNILKPYVKIFNDSTNIMHAKWQRLISDG 185 Query: 552 GARCDLHDVLLRLMFDMTCNLVFGVDPGCLQIGLPSLPLARAMDDVLETLFLRHVIPPAC 731 AR D+ + + + D VF D C + S A+ ++ + RH P Sbjct: 186 SARLDMFEHVSLMTLDSLQKCVFSFDSNCQE---KSSEYIAAILELSALVAKRHQQPLMF 242 Query: 732 WRLMYRYGFGPE-KKMAVARRIIDRFAADTIVKRRYS-------GHKLRGEGITESSDIL 887 L+Y P+ + A ++ F D +++ R+ L+ + +++ D + Sbjct: 243 MDLLYN--LTPDGMRFRKACNVVHEFT-DAVIRERHRTLPDQGLDDFLKSKAKSKTLDFI 299 Query: 888 SFFICN--DDASEHSDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELA 1061 + + +D E SDE +R A +F G DTT + LSW Y L +P ++ E+ Sbjct: 300 DVLLLSKDEDGKELSDEDIRAEADTFMFEGHDTTASGLSWILYNLARHPEYQERCRQEVQ 359 Query: 1062 PIAARKKVDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKA 1241 + ++ ++ ++ +L+ + +L + E LRL+P V + + T + +LP G I Sbjct: 360 ELLRGREPEE---IEWDDLAQLPFLTMCIKESLRLHPPVTVISRCCTQDILLPDGRTIPK 416 Query: 1242 GDKILVYSYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEV 1421 G L+ + + VW D + P R+ D ++ P FI F+AGPR C+G+ Sbjct: 417 GIICLISIFGIHHNPSVW-PDPEVYDPFRF--DPENIKDSSPLAFIPFSAGPRNCIGQTF 473 Query: 1422 AFTQMKTVAATVLWNFTL 1475 A ++MK A L F L Sbjct: 474 AMSEMKVALALTLLRFRL 491
>Q9VVN6:CP312_DROME Probable cytochrome P450 312a1 - Drosophila melanogaster (Fruit fly)| Length = 510 Score = 108 bits (269), Expect = 1e-22 Identities = 112/479 (23%), Positives = 201/479 (41%), Gaps = 22/479 (4%) Frame = +3 Query: 153 PTEWPLLGHLLSTLANVSNLHDW--ATGVLATTRYNFAAHMGLTGVRFFLTCDPSNVRHI 326 P P +GHL LA + H AT ++ ++ A + + + + C+P +++ + Sbjct: 37 PPALPFIGHL-HILAKLVGPHPLRRATEMINEHLHDHRAKLWMGTKLYLVDCNPKDIQAL 95 Query: 327 FISNSINYPRGEEYADIFDVLGDGIFNADGESWRRQRAKSQLIMASPRFRSFSARCTRDK 506 + + + +Y + L +G+F + E W +R + F A +K Sbjct: 96 CSAQQL-LQKTNDYRVFENWLCEGLFTSGFEKWSHRRKIVMPAFNYTMIKQFVA--VFEK 152 Query: 507 VERSLLPFLAHAADVGARCDLHDVLLRLMFDMTCNLVFGVDPGCLQIGLPSLPLARAMDD 686 R LL +A A+ G + D ++ D C GV +G S + +D Sbjct: 153 QSRILLTNVAKFAESGDQIDFLQLISCFTLDTICETALGVS-----VGSQSSAKSEYLDA 207 Query: 687 VLETLFLRHVIPPACWRLMYRYGF--------GPEKKM---------AVARRIIDRFAAD 815 V L +I + YR F E+++ + ++ ID D Sbjct: 208 VKSILV---IIDKRLKNIFYRNSFIFKRTSHYKREQELIKTLHGFTEGIIQKRIDEINQD 264 Query: 816 TIVKRRYSGHKLRGEGITESSDILSFFICND--DASEHSDEFLRDTAVNLLFAGRDTTGA 989 R Y +G+ + L + + D + + +R+ ++F G D T Sbjct: 265 A-ENRNYQSSDAELDGVKRTLCFLDTLLLSKGPDGKPLTVKDIREEVDTIIFGGFDLTAT 323 Query: 990 VLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAALCECLRLY 1169 L++F Y + +P +Q +E+ + + K + + + +L +L A + E LR+Y Sbjct: 324 TLNFFMYNMTLHPEHQQRCREEVWSVCGKDKSEPISIEQVRQLE---FLEACIKETLRMY 380 Query: 1170 PSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERW-ITDDG 1346 PS P+T + AT N + + I G +++ MGR + + D M F P+RW I + Sbjct: 381 PSGPLTARKATANCTI-NDFFIPKGSDVIISPIYMGRCKDFF-PDPMVFKPDRWAIGAEP 438 Query: 1347 KLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLETVPGHTVKPKLSIVL 1523 K+ FI F AG R+C+G+ A +K V A +L NF E + VK KL+ V+ Sbjct: 439 KIE---ATTFIPFMAGARSCMGQRYAMVMLKMVLAHLLRNFLFEPLGERQVKLKLNFVI 494
>Q64462:CP4B1_MOUSE Cytochrome P450 4B1 - Mus musculus (Mouse)| Length = 511 Score = 107 bits (266), Expect = 2e-22 Identities = 66/211 (31%), Positives = 101/211 (47%) Frame = +3 Query: 924 SDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVL 1103 SD LR +F G DTT + +SWF Y + P +Q +E+ R+ + D Sbjct: 301 SDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPMHQQRCREEV-----REILGDRDSF 355 Query: 1104 DASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRM 1283 +L+ M YL + EC RLYP VP ++ + G + AG I ++ Y++ R Sbjct: 356 QWDDLAQMTYLTMCMKECFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLISLHIYALHRN 415 Query: 1284 EGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLW 1463 VW D F P R+ ++ RH P+ F+ F+AGPR C+G++ A +MK V A L Sbjct: 416 SAVW-PDPEVFDPLRFSPENMTGRH--PFAFMPFSAGPRNCIGQQFAMNEMKVVTALCLL 472 Query: 1464 NFTLETVPGHTVKPKLSIVLHMKNGLAVTVK 1556 F P ++L KNG+ + +K Sbjct: 473 RFEFSPDPSKIPIKVPQLILRSKNGIHLYLK 503
>P30610:CP52H_CANTR Cytochrome P450 52A8 - Candida tropicalis (Yeast)| Length = 517 Score = 106 bits (265), Expect = 3e-22 Identities = 108/438 (24%), Positives = 184/438 (42%), Gaps = 24/438 (5%) Frame = +3 Query: 312 NVRHIFISNSINYPRGEEYADIFDVLGDGIFNADGESWRRQRAKSQLIMASPRF-RSFSA 488 N++ + + ++ G+ + +LGDGIF DG+ W+ RA M P+F R A Sbjct: 102 NIKALLATQFSDFSLGKRHTLFKPLLGDGIFTLDGQGWKHSRA-----MLRPQFAREQVA 156 Query: 489 RCTRDKVERSLLPFLAHAA-DVGARCDLHDVLLRLMFDMTCNLVFGVDPGCLQ---IG-- 650 T + LL H + G D+ ++ R D +FG L+ IG Sbjct: 157 HVTSLEPHFQLLK--KHMVKNKGGFFDIQELFFRFTVDSATEFLFGESVHSLKDETIGSY 214 Query: 651 ------LPSLPLARAMDDVLETLFLRHVIPPACWRLMYRYGFGPEKKMAVARRIIDRFAA 812 + A + + E L +R ++ Y ++ +++ +F Sbjct: 215 QDDIDFVGRKDFAESFNKAQEYLAIRTLVQDF-------YYLVNNQEFRDCNKLVHKFT- 266 Query: 813 DTIVKRRYSGHKLRGEGITESSDILSFFICNDDASEHSDEFLRDTAVNLLFAGRDTTGAV 992 + V+R E + + S + F+ LRD ++N+L AGRDT+ + Sbjct: 267 NYYVQRALDATP---EELEKQSGYV--FLYELVKQTRGPNVLRDQSLNILLAGRDTSAGL 321 Query: 993 LSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAALCECLRLYP 1172 LS+ + L NP + + +++ + + + L YL A L E LR+YP Sbjct: 322 LSFAVFELARNPHIWAKLREDVESQFGLGEQSRIEEITFESLKRCGYLKAFLNETLRVYP 381 Query: 1173 SVPITHKAATHNDVLPSGHEIKAGDKILV-------YSYSMGRMEGV-WGKDCMEFSPER 1328 SVP + AT N LP G +LV Y + ++ V +G D EF PER Sbjct: 382 SVPRNFRIATKNTTLPRGGGSDGNSPVLVKKGEAVSYGINSTHLDPVYYGDDAAEFRPER 441 Query: 1329 WITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNF-TLETVPGHTVKP 1505 W + + + ++ FN GPR CLG++ A T+ V + +F TLE P P Sbjct: 442 W---NEPSTRKLGWAYLPFNGGPRICLGQQFALTEAGYVLVRLAQSFDTLELKPPVVYPP 498 Query: 1506 K--LSIVLHMKNGLAVTV 1553 K ++ + +++G V + Sbjct: 499 KRLTNLTMSLQDGTIVKI 516
>P98187:CP4F8_HUMAN Cytochrome P450 4F8 - Homo sapiens (Human)| Length = 520 Score = 106 bits (265), Expect = 3e-22 Identities = 111/450 (24%), Positives = 191/450 (42%), Gaps = 31/450 (6%) Frame = +3 Query: 300 CDPSNVRHIF-ISNSINYPRGEEYADIFDVLGDGIFNADGESWRRQRAKSQLIMASPRFR 476 C P VR + S++I Y + LGDG+ + G+ WR R + +P F Sbjct: 102 CHPDIVRSVINTSDAITDKDIVFYKTLKPWLGDGLLLSVGDKWRHHRR-----LLTPAFH 156 Query: 477 -----------SFSARCTRDKVERSLLPFLAHAADVGARC-DLHDVLLRLMFDMTCNLVF 620 S SA K +R + G+ C D+ + + + D +F Sbjct: 157 FNILKPYIKIFSKSANIMHAKWQRLAME--------GSTCLDVFEHISLMTLDSLQKCIF 208 Query: 621 GVDPGCLQ---------IGLPSLPLARAMDDVLETLFLRHVIPPACWRLMYRYGFGPEKK 773 D C + + L +L + R FL + P C R +R Sbjct: 209 SFDSNCQEKPSEYITAIMELSALVVKRNNQFFRYKDFLYFLTP--CGRRFHR-------- 258 Query: 774 MAVARRIIDRFAADTIVKRRYS------GHKLRGEGITESSDILSFFICNDDAS--EHSD 929 A R++ F I +RR + L+ + +++ D + + ++D + E SD Sbjct: 259 ---ACRLVHDFTDAVIQERRRTLTSQGVDDFLQAKAKSKTLDFIDVLLLSEDKNGKELSD 315 Query: 930 EFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDA 1109 E +R A +F G DTT + LSW Y L +P ++ E+ + ++ + ++ Sbjct: 316 EDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELLKDREPKE---IEW 372 Query: 1110 SELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEG 1289 +L+ + +L L E LRL+P +P + T + VLP I G+ + +++ Sbjct: 373 DDLAQLPFLTMCLKESLRLHPPIPTFARGCTQDVVLPDSRVIPKGNVCNINIFAIHHNPS 432 Query: 1290 VWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNF 1469 VW D + P R+ ++ + R P FI F+AGPR C+G++ A +MK V A L F Sbjct: 433 VW-PDPEVYDPFRFDPENAQKRS--PMAFIPFSAGPRNCIGQKFAMAEMKVVLALTLLRF 489 Query: 1470 TLETVPGHTVKPKL-SIVLHMKNGLAVTVK 1556 + +P H + IVL ++GL + V+ Sbjct: 490 RI--LPDHREPRRTPEIVLRAEDGLWLRVE 517
>P33274:CP4F1_RAT Cytochrome P450 4F1 - Rattus norvegicus (Rat)| Length = 524 Score = 106 bits (265), Expect = 3e-22 Identities = 92/377 (24%), Positives = 163/377 (43%), Gaps = 14/377 (3%) Frame = +3 Query: 387 LGDGIFNADGESWRRQRAKSQLIMASPRFRSFS-----ARCTRDKVERSLLPFLAHAADV 551 LGDG+ + G+ W R R M +P F F+ + D + ++ Sbjct: 132 LGDGLLVSAGDKWSRHRR-----MLTPAFH-FNILKPYVKIFNDSTNIMHAKWKRLISEG 185 Query: 552 GARCDLHDVLLRLMFDMTCNLVFGVDPGCLQIGLPSLPLARAMDDVLETLFLRHVIPPAC 731 +R D+ + + + D VF D C + S A+ ++ + RH P Sbjct: 186 SSRLDMFEHVSLMTLDSLQKCVFSFDSNCQE---KSSEYIAAILELSALVAKRHQQPLLF 242 Query: 732 WRLMYRYGFGPE-KKMAVARRIIDRFAADTIVKRRYS------GHKLRGEGITESSDILS 890 L+Y P+ + A ++ F I +RR + L+ + +++ D + Sbjct: 243 MDLLYN--LTPDGMRFHKACNLVHEFTDAVIRERRRTLPDQGLDEFLKSKAKSKTLDFID 300 Query: 891 FFIC--NDDASEHSDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAP 1064 + ++D E SDE +R A +F G DTT + LSW Y L +P ++ E+ Sbjct: 301 VLLLTKDEDGKELSDEDIRAEADTFMFEGHDTTASGLSWILYNLANDPEYQERCRQEVQE 360 Query: 1065 IAARKKVDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAG 1244 + + ++ ++ +L+ + +L + E LRL+P V + + T + +LP G I G Sbjct: 361 LLRDRDPEE---IEWDDLAQLPFLTMCIKESLRLHPPVTVISRCCTQDILLPDGRTIPKG 417 Query: 1245 DKILVYSYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVA 1424 L+ + + VW D ++P R+ D ++ P FI F+AGPR C+G+ A Sbjct: 418 IICLISIFGIHHNPSVW-PDPEVYNPFRF--DPENIKDSSPLAFIPFSAGPRNCIGQTFA 474 Query: 1425 FTQMKTVAATVLWNFTL 1475 ++MK A L F L Sbjct: 475 MSEMKVALALTLLRFRL 491
>P51869:CP4F4_RAT Cytochrome P450 4F4 - Rattus norvegicus (Rat)| Length = 522 Score = 105 bits (263), Expect = 5e-22 Identities = 111/484 (22%), Positives = 200/484 (41%), Gaps = 15/484 (3%) Frame = +3 Query: 150 EPTEWP-LLGHLLSTLANVSNLHDWATGVLATTRYNFAAHMGLTGVRFFLTCDPSNVRHI 326 +P +W LGHL L T ++AT F +G + C P +R + Sbjct: 53 QPPKWNWFLGHLGMITPTEQGLKQ-VTKLVATYPQGFMTWLGPI-LPIITLCHPDVIRSV 110 Query: 327 F-ISNSINYPRGEEYADIFDVLGDGIFNADGESWRRQRAKSQLIMASPRFRSFS-----A 488 S S+ Y+ + LGDG+ +DG+ W R M +P F F+ Sbjct: 111 LSASASVALKEVIFYSFLKPWLGDGLLLSDGDKWSCHRR-----MLTPAFH-FNILKPYV 164 Query: 489 RCTRDKVERSLLPFLAHAADVGARCDLHDVLLRLMFDMTCNLVFGVDPGCLQIGLPSLPL 668 + D + A+ AR D+ + + D VF D C + + Sbjct: 165 KIFNDSTNIMHAKWQDLASGGSARLDMFKNISLMTLDSLQKCVFSFDSNCQEKPSEYISA 224 Query: 669 ARAMDDVLETLFLRHVIPPACWRLMYRYGFGPEKKMAVARRIIDRFAADTIVKRRY---S 839 + ++ + + ++ + G ++ A +++ F I RR S Sbjct: 225 ILELSALVAKRYQQLLLHTDSLYQLTHNG----RRFHKACKLVHNFTDAVIQGRRRALPS 280 Query: 840 GHK---LRGEGITESSDILSFFIC--NDDASEHSDEFLRDTAVNLLFAGRDTTGAVLSWF 1004 H+ L+ + +++ D + + ++D E SDE +R A +F G DTT + LSW Sbjct: 281 QHEDDILKAKARSKTLDFIDVLLLTKDEDGKELSDEDIRAEADTFMFEGHDTTASGLSWI 340 Query: 1005 FYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAALCECLRLYPSVPI 1184 Y L +P ++ E+ + ++ + ++ +L+ + +L + E LRL+P V + Sbjct: 341 LYNLARHPEYQERCRQEVRELLRDRESTE---IEWDDLAQLPFLTMCIKESLRLHPPVTV 397 Query: 1185 THKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQP 1364 + T + VLP G I G ++ ++ VW D + P R+ D ++ + Sbjct: 398 ISRRCTQDIVLPDGRVIPKGVICIINIFATHHNPTVW-PDPEVYDPFRF--DPENIKDRS 454 Query: 1365 PYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLETVPGHTVKPKLSIVLHMKNGLA 1544 P FI F+AGPR C+G+ A +MK A L F + + K ++L + GL Sbjct: 455 PLAFIPFSAGPRNCIGQTFAMNEMKVALALTLLRFRV-LPDDKEPRRKPELILRAEGGLW 513 Query: 1545 VTVK 1556 + V+ Sbjct: 514 LRVE 517
>O48921:C97B2_SOYBN Cytochrome P450 97B2 - Glycine max (Soybean)| Length = 576 Score = 105 bits (263), Expect = 5e-22 Identities = 115/474 (24%), Positives = 195/474 (41%), Gaps = 48/474 (10%) Frame = +3 Query: 288 FFLTCDPSNVRHIFISNSINYPRGEEYADIFD-VLGDGIFNADGESWRRQRAKSQLIMAS 464 F + DP RHI N+ +Y +G ADI + ++G G+ AD ++W+++R + + Sbjct: 118 FVVVSDPIVARHILRENAFSYDKGV-LADILEPIMGKGLIPADLDTWKQRRR-----VIA 171 Query: 465 PRFRSF----SARCTRDKVERSLLPFLAHAADVG------ARCDLHDVLLRLMFDMTCNL 614 P F + + ER++L F G DL L D+ Sbjct: 172 PAFHNSYLEAMVKIFTTCSERTILKFNKLLEGEGYDGPDSIELDLEAEFSSLALDIIGLG 231 Query: 615 VFGVDPGCLQIGLPSLPLARAMDDVL------ETLFLRH-VIPPACWRLMYRYGFGPEKK 773 VF D G + P+ +A+ L T ++ + IP A W + + F + K Sbjct: 232 VFNYDFGSVT---KESPVIKAVYGTLFEAEHRSTFYIPYWKIPLARWIVPRQRKFQDDLK 288 Query: 774 MAVARRIIDRFAADTIVKRRYSG-HKLRGEGITESSDI-LSFFICNDDASEHSDEFLRDT 947 V +D + R+ + KL+ D L F+ + ++ D LRD Sbjct: 289 --VINTCLDGLIRNAKESRQETDVEKLQQRDYLNLKDASLLRFLVDMRGADVDDRQLRDD 346 Query: 948 AVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSM 1127 + +L AG +TT AVL+W +LL +NP + E+ + + L + Sbjct: 347 LMTMLIAGHETTAAVLTWAVFLLAQNPSKMKKAQAEVDLVLGTGRP------TFESLKEL 400 Query: 1128 VYLHAALCECLRLYPSVPITHKAATHNDVLPSGHE-------IKAGDKILVYSYSMGRME 1286 Y+ + E LRLYP P+ + + +DVLP GH+ I AG + + Y++ R Sbjct: 401 QYIRLIVVEALRLYPQPPLLIRRSLKSDVLPGGHKGEKDGYAIPAGTDVFISVYNLHRSP 460 Query: 1287 GVWGKDCMEFSPERWITD------DGKLRHQP--------------PYKFIAFNAGPRTC 1406 W + +F PER++ +G P + F+ F GPR C Sbjct: 461 YFWDRP-DDFEPERFLVQNKNEEIEGWAGLDPSRSPGALYPNEVISDFAFLPFGGGPRKC 519 Query: 1407 LGKEVAFTQMKTVAATVLWNFTLETV-PGHTVKPKLSIVLHMKNGLAVTVKRRN 1565 +G + A + +L NF +E +V+ +H KNG+ +K+R+ Sbjct: 520 VGDQFALMESTVALTMLLQNFDVELKGTPESVELVTGATIHTKNGMWCRLKKRS 573
>Q27520:C13A1_CAEEL Putative cytochrome P450 CYP13A1 - Caenorhabditis elegans| Length = 519 Score = 105 bits (263), Expect = 5e-22 Identities = 123/509 (24%), Positives = 205/509 (40%), Gaps = 39/509 (7%) Frame = +3 Query: 72 WY-WFVGLVCCFLSYYRRLQS--KKTTKEEPTEWPLLGHLLSTLAN----VSNLHDWATG 230 W+ WF + SYY + ++ P +P+LG L++L N +W Sbjct: 5 WFPWFSAIFVAVFSYYIWQWTFWRRRGVVGPMGFPVLGVFLNSLDNNFPFPLQCREWTK- 63 Query: 231 VLATTRYNFAAHMGLTG--VRFFLTCDPSNVRHIFISNSINY---PRGEEYADIFDVLGD 395 F G T ++ + DP V +F++ N+ R D Sbjct: 64 -------KFGKIYGFTEGTLKTLVISDPELVHEVFVTQYDNFYGRKRNPIQGDSEKEKRT 116 Query: 396 GIFNADGESWRRQRAKSQLIMASPRFRSFSARCTRDKVERSLLPFLAHAADVGARCDLHD 575 +F A G W+R RA ++SP F + S R VE S L L H A D Sbjct: 117 NLFAAQGFRWKRLRA-----ISSPTFSNSSLRKLYQTVEDSALELLRHIEKQSAGGKQID 171 Query: 576 VLLRLMFDMTCNLVFGVDPGCLQIGL---PSLPL-ARAMDDVLETLFLRHVIPPACWRLM 743 +L+ + T +++ + G + P +P+ ++ LFL I P + Sbjct: 172 -MLKFYQEFTLDVIGRIAMGQTDSQMFKNPIMPIVSKLFQGNFAKLFLIGGIFPTFLVEI 230 Query: 744 YRYGFGPEKKMAVARRIIDRFAADTI---VKRRYSGHKLRGEGITESSDILSFFICN--- 905 R K+ R+I + D I +K+R K G I E +D + F+ Sbjct: 231 IRQILLKNLKVGSFRKI-NEITLDAIHNRIKQREEDQK-NGIEIGEPADFIDLFLDAKAE 288 Query: 906 --DDASEHSDEFLRDTAVN---------------LLFAGRDTTGAVLSWFFYLLCENPRV 1034 + E++ +F + T L AG DTT LS+ YLL +P + Sbjct: 289 DVEHFGENNGDFSKSTTYTNRQLTTEEIVGQCTVFLIAGFDTTALSLSYATYLLATHPEI 348 Query: 1035 EQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDV 1214 ++ + +E+ R+ + V +D +LS + Y+ E LRLYP + + Sbjct: 349 QKKLQEEVN----RECPNPEVTID--QLSKLKYMECVFKEALRLYPLGAFANSRRCMRNT 402 Query: 1215 LPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAG 1394 +++ G I V ++++ +WG D +F PERW T + +Q +I F G Sbjct: 403 KLGNMKVEVGTMIQVDTWTLHTDPNIWGDDAEDFKPERWQTPNSDQIYQKS-GYIPFGLG 461 Query: 1395 PRTCLGKEVAFTQMKTVAATVLWNFTLET 1481 PR C+G +A+ + K + +L FT ET Sbjct: 462 PRQCIGMRLAYMEEKILLVHILRKFTFET 490
>P13584:CP4B1_HUMAN Cytochrome P450 4B1 - Homo sapiens (Human)| Length = 511 Score = 105 bits (262), Expect = 6e-22 Identities = 66/218 (30%), Positives = 102/218 (46%) Frame = +3 Query: 903 NDDASEHSDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKK 1082 ++D + SD LR +F G DTT + +SWF Y + P + +E+ R+ Sbjct: 294 DEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEV-----REI 348 Query: 1083 VDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVY 1262 + D +L M YL + E RLYP VP ++ + G + AG I ++ Sbjct: 349 LGDQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMH 408 Query: 1263 SYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKT 1442 Y++ R VW D F R+ T++ RH P+ F+ F+AGPR C+G++ A ++MK Sbjct: 409 IYALHRNSAVW-PDPEVFDSLRFSTENASKRH--PFAFMPFSAGPRNCIGQQFAMSEMKV 465 Query: 1443 VAATVLWNFTLETVPGHTVKPKLSIVLHMKNGLAVTVK 1556 V A L F P +VL KNG + +K Sbjct: 466 VTAMCLLRFEFSLDPSRLPIKMPQLVLRSKNGFHLHLK 503
>Q9VA27:CP4C3_DROME Cytochrome P450 4c3 - Drosophila melanogaster (Fruit fly)| Length = 535 Score = 103 bits (258), Expect = 2e-21 Identities = 71/232 (30%), Positives = 121/232 (52%), Gaps = 5/232 (2%) Frame = +3 Query: 885 LSFFICNDDASEH----SDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILD 1052 L+F DAS+ S+E +R+ +F G DTT A +SW +LL +P ++ +++ Sbjct: 311 LAFLDLLIDASKEGTVLSNEDIREEVDTFMFEGHDTTSAAISWTLFLLGCHPEYQERVVE 370 Query: 1053 ELAPIAARKKVDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHE 1232 EL I K + L M YL + + LRL+PSVP+ + DV G Sbjct: 371 ELDSIFGDDKETPATM---KNLMDMRYLECCIKDSLRLFPSVPMMARMVGE-DVNIGGKI 426 Query: 1233 IKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLG 1412 + AG + ++ +Y++ R V+ K +F+P+ ++ ++ RH P+ +I F+AGPR C+G Sbjct: 427 VPAGTQAIIMTYALHRNPRVFPKP-EQFNPDNFLPENCAGRH--PFAYIPFSAGPRNCIG 483 Query: 1413 KEVAFTQMKTVAATVLWNFTLETVPGHTVKPKL-SIVLHMKNGLAVTVKRRN 1565 ++ A + K V +TVL + +E V L ++L K+GL V + R+ Sbjct: 484 QKFAILEEKAVISTVLRKYKIEAVDRREDLTLLGELILRPKDGLRVKITPRD 535
>Q27518:C13A2_CAEEL Putative cytochrome P450 CYP13A2 - Caenorhabditis elegans| Length = 515 Score = 103 bits (258), Expect = 2e-21 Identities = 103/451 (22%), Positives = 185/451 (41%), Gaps = 39/451 (8%) Frame = +3 Query: 285 RFFLTCDPSNVRHIFISNSINY-----------PRGEEYADIFDVLGDGIFNADGESWRR 431 R + DP+ V IF+ N+ P E+ + A G W+R Sbjct: 78 RTLVVADPAMVHEIFVKQFDNFYGRKLNPIQGNPEKEQRVHLLA--------AQGYRWKR 129 Query: 432 QRAKSQLIMASPRFRSFSARCTRDKVERSLLPFLAHAADVGARCDLHDVLLRLMFDMTCN 611 R ++S F + S + + VE S L L H A + D +LR + T + Sbjct: 130 LRT-----ISSQSFSNASLKKMKRTVEDSALELLRHIEKQTAGGEQID-MLRFYQEYTMD 183 Query: 612 LVFGVDPGCLQIGLPSLPLARAMDDVL-----ETLFLRHVIPPA---CWRLMYRYGFGPE 767 ++ G + P+ + ++ + + V PP L +++ P Sbjct: 184 VIGRFAMGQTDSMMFKNPIVNVVREIFCGSRKNLMLICQVFPPIGQFIRDLTFKFPRIPA 243 Query: 768 KKMAVARRIIDRFAADTIVKRRYSGHKLRGEGITESSDILSFFI------------CNDD 911 K+ + D + R + +G E D + F+ +D Sbjct: 244 FKLYSIMQ-------DVVAARIAQREREKGAESGEPQDFIDLFLDARSDDVDFSAEARED 296 Query: 912 ASEHSDEFLRDTAVN--------LLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPI 1067 S+ + + ++ + + L G DTT LS+ YLL NP++++ +++E+A Sbjct: 297 FSKRNLKITKELSADEVVGQCFLFLIGGFDTTALSLSYVTYLLAVNPKIQEKVIEEIARE 356 Query: 1068 AARKKVDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGD 1247 +V+ +L + Y+ + E LRLYP I++ +G +I+AG Sbjct: 357 FGTSEVE------FEKLGRLKYMDCVIKEALRLYPLASISNSRKCMKTTTVNGVKIEAGV 410 Query: 1248 KILVYSYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAF 1427 + + ++S+ +WG+D EF PERW TD+ L H+ Y + F GPR C+G +A Sbjct: 411 YVQMDTWSLHYDPELWGEDVKEFKPERWSTDE-PLEHKGAY--LPFGLGPRQCIGMRLAI 467 Query: 1428 TQMKTVAATVLWNFTLETVPGHTVKPKLSIV 1520 + K + +L N+T ET G+ + L +V Sbjct: 468 MEQKILLTHLLKNYTFET--GNKTRIPLKLV 496
>O04164:C71A6_NEPRA Cytochrome P450 71A6 - Nepeta racemosa (Catmint) (Raceme catnip)| Length = 511 Score = 102 bits (254), Expect = 5e-21 Identities = 120/508 (23%), Positives = 205/508 (40%), Gaps = 21/508 (4%) Frame = +3 Query: 102 FLSYYRRLQSKKTTKEEPTEWPLLG--HLLSTLANVSNLHDWATGVLATTRYNFAAHMGL 275 FL +RR S KT P + P+LG H L T + S + RY + Sbjct: 14 FLKKWRRSYSGKTPPPSPPKLPVLGNLHQLGTFPHRSLQS-------LSRRYGPVMQLHF 66 Query: 276 TGVRFFLTCDPSNVRHIFISNSINYPRGEEYADIFDVLGDG---IFNADGESWRRQRAKS 446 V + P R I + +N+ + +L D F GE WR+ R+ Sbjct: 67 GSVPVLVASSPEAAREIMKNQDLNFSNRPNLSIPRRLLYDNHDVAFAPYGEYWRQIRSIC 126 Query: 447 QL-IMASPRFRSFSARCTRDKVERSLLPFLAHAADVG--ARCDLHDVLLRLMFDMTCNLV 617 L ++++ R +SF R R++ ++ + A +L D+L L D+ C + Sbjct: 127 VLQLLSNKRVQSF--RRVREEETSIMVEKIMQLQKTTPTAAVNLTDLLTCLTNDVFCRIA 184 Query: 618 FGVDPGCLQIGLPSLPLARAMDDVLETLFLRHVIPP---ACWRLMYRYGFGPEKKMAVAR 788 G G G + ++ E L + P W R G ++++ Sbjct: 185 LGKKYGGTTTGDGEYHVRSLKKNLAEFYVLLGISPLWEYIPWLEWTRRFDGVDRRIEEVS 244 Query: 789 RIIDRFAADTIVKRRYSGHKLRGEGITESSD---------ILSFFICNDDASEHSDEF-L 938 R D F I + R + E T D +L F N+ +S D+ + Sbjct: 245 RTFDEFLGKVIQEHRVRDKR---EDTTVVGDTVGLDFVDLLLQFQRENERSSSPVDDLTI 301 Query: 939 RDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASEL 1118 + +++ AG DTT L W L +NPR +++ E+ +A K ++ S+L Sbjct: 302 KAVILDMFLAGTDTTVTALEWALSELIKNPRAMKILQKEVRGVAGSKGE-----IEESDL 356 Query: 1119 SSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWG 1298 M YL A + E LRL+ VP+ + D G+++ +G ++L+ +++GR VW Sbjct: 357 EKMPYLKAVMKESLRLHAPVPLLVPRESTRDTKVLGYDVASGTRVLINCWAIGRDSSVW- 415 Query: 1299 KDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLE 1478 ++ F PER++ R ++ I F +G R C G A + AT++ F + Sbjct: 416 EESETFLPERFLETSIDYRGM-HFELIPFGSGRRGCPGATFAAAIDELALATLVHKFDFK 474 Query: 1479 TVPGHTVKPKLSIVLHMKNGLAVTVKRR 1562 G V+ L M G T+ ++ Sbjct: 475 LPNGVRVED-----LDMSEGSGFTIHKK 497
>P30612:CP52P_CANTR Cytochrome P450 52C1 - Candida tropicalis (Yeast)| Length = 505 Score = 101 bits (252), Expect = 9e-21 Identities = 103/416 (24%), Positives = 182/416 (43%), Gaps = 19/416 (4%) Frame = +3 Query: 279 GVRFFLTCDPSNVRHIFISNSIN-YPRGEEYADIFDVLGDGIFNADGESWRRQRAKSQLI 455 G ++T D N+RHI + +N + G + +GDGIF ++G+SW+ R + + Sbjct: 86 GKTTYVTKDIENIRHILSATEMNSWNLGARPIALRPFIGDGIFASEGQSWKHSRIMLRPV 145 Query: 456 MASPRFRSFSARCTRDKV--------ERSLLPF--LAHAADVGARCDLHDVLLRLMFDMT 605 A + ++ ++ E L F LAH + D LL D Sbjct: 146 FAKEHVKQITSMEPYVQLLIKIIKNHEGEPLEFQTLAHLFTIDYSTDF---LLGESCDSL 202 Query: 606 CNLVFGVDPGCLQIGLPSLPLARAMDDVLETLFLRHVIPPACWRLMYRYGFGPEKKMAVA 785 + + L L L A + + + +R ++ + LMY F + + + Sbjct: 203 KDFLGEESNSTLDTSL-RLAFASQFNKTQQQMTIRFMLGKLAF-LMYPKSF--QYSIQMQ 258 Query: 786 RRIIDRFAADTIVKRRYSGHKLRGEGITESSDILSFFICNDDASEHSDEFLRDTAVNLLF 965 + +D + D +V S +L S +L + + + + L+D +++L Sbjct: 259 KDFVDVYI-DRVVGM--SEEELNNH---PKSYVLLYQLARQTKNR---DILQDELMSILL 309 Query: 966 AGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAA 1145 AGRDTT ++L++ F+ L +P V + +E+ + D+ + + YL Sbjct: 310 AGRDTTASLLTFLFFELSHHPEVFNKLKEEI-----ERHFPDVESVTFGTIQRCDYLQWC 364 Query: 1146 LCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYS--------YSMGRMEGVWGK 1301 + E +RL+PSVP + A ++ V+P G D ILV+ YS+ R E +G Sbjct: 365 INETMRLHPSVPFNFRTAANDTVIPRGGGKSCTDPILVHKGEQVLFSFYSVNREEKYFGT 424 Query: 1302 DCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNF 1469 + +F+PERW LR +FI F+AGPR CLG+++ + V +L F Sbjct: 425 NTDKFAPERW---SESLRRT---EFIPFSAGPRACLGQQLPRVEASYVTIRLLQTF 474
>Q9V558:CP4P1_DROME Cytochrome P450 4p1 - Drosophila melanogaster (Fruit fly)| Length = 513 Score = 101 bits (252), Expect = 9e-21 Identities = 107/436 (24%), Positives = 178/436 (40%), Gaps = 27/436 (6%) Frame = +3 Query: 336 NSINYP----RGEEYADIFDVLGDGIFNADGESWRRQRAKSQLIMASPRFRSFSARCTRD 503 N +N+P +G Y + L G+ + G+ W +R M +P F ++ Sbjct: 104 NVLNHPNLITKGLVYNFLHPFLRTGLLTSTGKKWHARRK-----MLTPTFHFNILNQFQE 158 Query: 504 KVERSLLPFLAH-AADVGARCDLHDVLLRLMFDMTCNLVFGVDPGCLQIGLPSLPLARAM 680 + FL LHDV+ R + C GV L R Sbjct: 159 IFKTESQKFLLQFEGQDEVTITLHDVIPRFTLNSICETAMGVK---LDEMAEKGDRYREN 215 Query: 681 DDVLETLFLRHVIPPACW--RLMYRYGFGPEKKMAVARRIIDRFAADTIVKRRYSGHKLR 854 +E F+R + P W +L + K A A ++ RF+++ I KRR L Sbjct: 216 FSQIEECFIRRLSNPLLWGDKLFEMFA---AKDFASALDVVHRFSSEIIAKRR----DLL 268 Query: 855 GEGITESSDILSFFICNDDASEHSDEF-LRDTAV------------------NLLFAGRD 977 + + +SS +DD F + DT + L+F G D Sbjct: 269 KDELDKSSST-----ADDDGFVSKKRFAMLDTLIYAEKDGLIDHIGICEEVDTLMFEGYD 323 Query: 978 TTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAALCEC 1157 TT L + + NP +++ E+ DD+ LD +L+ + YL + E Sbjct: 324 TTSIGLIFGLMNMSLNPDKQELCYQEIQEHID----DDLSNLDVGQLNKLKYLEYFMKET 379 Query: 1158 LRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWIT 1337 RL+PSVPI + A L +G + G +I ++ + + R W EF PER++ Sbjct: 380 TRLFPSVPIMGREAVQETELANGLILPKGAQITIHVFDIHRNAKYWDSP-EEFRPERFLP 438 Query: 1338 DDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNF-TLETVPGHTVKPKLS 1514 ++ + RH Y ++ F+AG R C+GK+ A +MKT+ +L F L+ + + Sbjct: 439 ENVQDRH--TYAYVPFSAGQRNCIGKKYAMQEMKTLMVVLLKQFKVLKAIDPQKIVFHTG 496 Query: 1515 IVLHMKNGLAVTVKRR 1562 I L ++ + V + RR Sbjct: 497 ITLRTQDKIRVKLVRR 512
>P20816:CP4A2_RAT Cytochrome P450 4A2 precursor - Rattus norvegicus (Rat)| Length = 504 Score = 101 bits (252), Expect = 9e-21 Identities = 80/316 (25%), Positives = 132/316 (41%), Gaps = 7/316 (2%) Frame = +3 Query: 633 GCLQIGLPSLPLARAMDDVLETLFLRHVIPPACWRLMYRYGFGPEKKMAVARRIIDRFAA 812 G +Q+ + S +A++D+ +F R + A + Y + +++ I Sbjct: 200 GSVQLDVNSRSYTKAVEDLNNLIFFR--VRSAFYGNSIIYNMSSDGRLSRRACQIAHEHT 257 Query: 813 DTIVKRRYSG-------HKLRGEGITESSDILSFFICNDDASEHSDEFLRDTAVNLLFAG 971 D ++K R + K R + + DIL F +D SDE LR +F G Sbjct: 258 DGVIKTRKAQLQNEEELQKARKKRHLDFLDIL-LFAKMEDGKSLSDEDLRAEVDTFMFEG 316 Query: 972 RDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAALC 1151 DTT + +SW FY L +P ++ +E+ I + D + L M Y + Sbjct: 317 HDTTASGISWVFYALATHPEHQERCREEVQSI-----LGDGTSVTWDHLDQMPYTTMCIK 371 Query: 1152 ECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERW 1331 E LRLY VP + + P G I G ++ + Y + W + F P R+ Sbjct: 372 EALRLYSPVPSVSRELSSPVTFPDGRSIPKGIRVTILIYGLHHNPSYWPNPKV-FDPSRF 430 Query: 1332 ITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLETVPGHTVKPKL 1511 D + H ++ F+ G R C+GK+ A ++K A L F L P P Sbjct: 431 SPDSPRHSHA----YLPFSGGARNCIGKQFAMNELKVAVALTLLRFELLPDPTRIPVPMP 486 Query: 1512 SIVLHMKNGLAVTVKR 1559 +VL KNG+ + +K+ Sbjct: 487 RLVLKSKNGIHLRLKK 502
>Q27514:C13A5_CAEEL Putative cytochrome P450 CYP13A5 - Caenorhabditis elegans| Length = 520 Score = 101 bits (251), Expect = 1e-20 Identities = 98/391 (25%), Positives = 163/391 (41%), Gaps = 30/391 (7%) Frame = +3 Query: 399 IFNADGESWRRQRAKSQLIMASPRFRSFSARCTRDKVERSLLPFLAHAADVGAR---CDL 569 + +A G W+R R ++SP F + + R VE +++ + H D A+ DL Sbjct: 117 LVSAQGHRWKRLRT-----LSSPTFSNKNLRKIMSTVEETVVELMRHLDDASAKGKAVDL 171 Query: 570 HDVLLRLMFDMTCNLVFGVDPGCLQIGLPSLPLARAM-DDVLETLFLRHVIPPACWRLMY 746 D D+ + G L P LP + + D + FL I P M+ Sbjct: 172 LDYYQEFTLDIIGRIAMGQTES-LMFRNPMLPKVKGIFKDGRKLPFLVSGIFPIAGT-MF 229 Query: 747 RYGFGPEKKMAVARRIIDRF--AADTIVKRRYSGHKLRGEGITESSDILSFFICNDDASE 920 R F + A I+ A + +++R + K E E D + F+ DA Sbjct: 230 REFFMRFPSIQPAFDIMSTVEKALNKRLEQRAADEKAGIEPSGEPQDFIDLFL---DARA 286 Query: 921 HSDEFLRDTAVNL------------------------LFAGRDTTGAVLSWFFYLLCENP 1028 + D F ++A+ L AG DTT LS+ YLL +P Sbjct: 287 NVDFFEEESALGFAKTEIAKVDKQLTFDEIIGQLFVFLLAGYDTTALSLSYSSYLLARHP 346 Query: 1029 RVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHN 1208 +++ + +E+ R+ + V D ++S + Y+ + E LR+YP I H Sbjct: 347 EIQKKLQEEVD----RECPNPEVTFD--QISKLKYMECVVKEALRMYPLASIVHNRKCMK 400 Query: 1209 DVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFN 1388 + G +I+ G + V ++++ VWG+D EF PERW + D + Y + F Sbjct: 401 ETNVLGVQIEKGTNVQVDTWTLHYDPKVWGEDANEFRPERWESGDELFYAKGGY--LPFG 458 Query: 1389 AGPRTCLGKEVAFTQMKTVAATVLWNFTLET 1481 GPR C+G +A + K + +L +T ET Sbjct: 459 MGPRICIGMRLAMMEKKMLLTHILKKYTFET 489
>P51870:CP4F5_RAT Cytochrome P450 4F5 - Rattus norvegicus (Rat)| Length = 526 Score = 100 bits (250), Expect = 2e-20 Identities = 100/404 (24%), Positives = 170/404 (42%), Gaps = 19/404 (4%) Frame = +3 Query: 387 LGDGIFNADGESWRRQRAKSQLIMASPRFRSFSARCTRDKVERSLLPFLAHAA------D 548 LGDG+F + G+ W R R + +P F F K+ + + HA + Sbjct: 132 LGDGLFLSSGDKWSRHRR-----LLTPAFH-FDILKPYVKIFNQSVNIM-HAKWKHLCLE 184 Query: 549 VGARCDLHDVLLRLMFDMTCNLVFGVDPGCLQIGLPSLPLARAMDDVLETLFLRHVIPPA 728 AR ++ + + + D +FG D C + PS ++ ++ L +L ++ Sbjct: 185 GSARLEMFENISLMTLDSLQKCLFGFDSNCQES--PSEYISAILE--LSSLIIKRSQQLF 240 Query: 729 CWRLMYRYGFGPEKKMAVARRIIDRFAADTIVKRRYSGHKLRGEGITE--------SSDI 884 + Y ++ A ++ F I +RR L +G E S Sbjct: 241 LYLDFLYYRTADGRRFRKACDLVHNFTDAVIRERR---RLLSSQGTDEFLESKTKSKSKT 297 Query: 885 LSFF----ICNDD-ASEHSDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMIL 1049 L F + D+ E SDE +R A +F G DTT + LSW Y L +P ++ Sbjct: 298 LDFIDVLLLAKDEHGKELSDEDIRAEADTFMFGGHDTTASALSWILYNLARHPEYQERCR 357 Query: 1050 DELAPIAARKKVDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGH 1229 E+ + ++ ++ ++ +L+ + +L + E LRL+P + T + VLP G Sbjct: 358 QEVWELLRDREPEE---IEWDDLAQLPFLTMCIKESLRLHPPAIDLLRRCTQDIVLPDGR 414 Query: 1230 EIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCL 1409 I G+ ++ + + VW D F P R+ D + + P FI F+AGPR C+ Sbjct: 415 VIPKGNICVISIFGIHHNPSVW-PDPEVFDPFRF--DSENRQKRSPLSFIPFSAGPRNCI 471 Query: 1410 GKEVAFTQMKTVAATVLWNFTLETVPGHTVKPKLSIVLHMKNGL 1541 G+ A +MK V A L F + + K I+L + GL Sbjct: 472 GQTFAMNEMKVVVALTLLRFRV-LPDDKEPRRKPEIILRAEGGL 514
>Q3MID2:CP4F3_RAT Cytochrome P450 4F3 - Rattus norvegicus (Rat)| Length = 524 Score = 100 bits (250), Expect = 2e-20 Identities = 98/405 (24%), Positives = 171/405 (42%), Gaps = 15/405 (3%) Frame = +3 Query: 387 LGDGIFNADGESWRRQRAKSQLIMASPRFRSFS-----ARCTRDKVERSLLPFLAHAADV 551 LGDG+ + G+ W R R M +P F F+ + D + A+ Sbjct: 132 LGDGLLLSTGDKWSRHRR-----MLTPAFH-FNILKPYVKIFNDSTNIMHAKWQRLASQG 185 Query: 552 GARCDLHDVLLRLMFDMTCNLVFGVDPGCLQIGLPSLPLARAMDDVLETLFLRHVIPPAC 731 AR D+ + + + D VF D C + PS + ++ L L R Sbjct: 186 SARLDMFEHISLMTLDSLQKCVFSFDSNCQE--KPSEYITAILE--LSALVARRHQSLLL 241 Query: 732 WRLMYRYGFGPEKKMAVARRIIDRFAADTIVKRRYS------GHKLRGEGITESSDILSF 893 ++ + + A R++ F I +RR + L+ + ++ D + Sbjct: 242 HVDLFYHLTRDGMRFRKACRLVHDFTDAVIRERRCTLPDQGGDDALKAKAKAKTLDFIDV 301 Query: 894 FICNDDASEH----SDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELA 1061 + + D EH SDE +R A +F G DTT + LSW Y L ++P ++ E+ Sbjct: 302 LLLSKD--EHGEALSDEDIRAEADTFMFGGHDTTASGLSWILYNLAKHPEYQERCRQEVR 359 Query: 1062 PIAARKKVDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKA 1241 + ++ ++ ++ +L+ + +L + E LRL+P + T + +LP G I Sbjct: 360 ELLRDREPEE---IEWDDLAQLPFLTMCIKESLRLHPPATAISRCCTQDIMLPDGRVIPK 416 Query: 1242 GDKILVYSYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEV 1421 G + + VW D ++P R+ D+GK R P FI F+AGPR C+G+ Sbjct: 417 GVICRISIFGTHHNPAVW-PDPEVYNPFRFDADNGKGR--SPLAFIPFSAGPRNCIGQTF 473 Query: 1422 AFTQMKTVAATVLWNFTLETVPGHTVKPKLSIVLHMKNGLAVTVK 1556 A ++MK A L F + + K ++L + GL + V+ Sbjct: 474 AMSEMKVALALTLLRFRV-LPDDKEPRRKPELILRAEGGLWLRVE 517
>Q86W10:CP4Z1_HUMAN Cytochrome P450 4Z1 - Homo sapiens (Human)| Length = 505 Score = 100 bits (249), Expect = 2e-20 Identities = 71/256 (27%), Positives = 111/256 (43%), Gaps = 2/256 (0%) Frame = +3 Query: 798 DRFAADTIVKRRYSGHKLRGEGITESSDILSFFIC--NDDASEHSDEFLRDTAVNLLFAG 971 D+ DT KRR+ D L + +++ + S+ L+ +FAG Sbjct: 270 DKLKQDTTQKRRW--------------DFLDILLSAKSENTKDFSEADLQAEVKTFMFAG 315 Query: 972 RDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAALC 1151 DTT + +SW Y L + P +Q DE+ R+ + D + LS M Y + Sbjct: 316 HDTTSSAISWILYCLAKYPEHQQRCRDEI-----RELLGDGSSITWEHLSQMPYTTMCIK 370 Query: 1152 ECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERW 1331 ECLRLY V + P G + AG + + +++ W +D F+P R+ Sbjct: 371 ECLRLYAPVVNISRLLDKPITFPDGRSLPAGITVFINIWALHHNPYFW-EDPQVFNPLRF 429 Query: 1332 ITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLETVPGHTVKPKL 1511 ++ + H PY FI F+AG R C+G+ A + K A L F L +P Sbjct: 430 SRENSEKIH--PYAFIPFSAGLRNCIGQHFAIIECKVAVALTLLRFKLAPDHSRPPQPVR 487 Query: 1512 SIVLHMKNGLAVTVKR 1559 +VL KNG+ V K+ Sbjct: 488 QVVLKSKNGIHVFAKK 503
>P51871:CP4F6_RAT Cytochrome P450 4F6 - Rattus norvegicus (Rat)| Length = 537 Score = 100 bits (249), Expect = 2e-20 Identities = 92/409 (22%), Positives = 173/409 (42%), Gaps = 11/409 (2%) Frame = +3 Query: 387 LGDGIFNADGESWRRQRAKSQLIMASPRFRSFSARCTRDKVERSLLPFLAHAADVGARCD 566 LGDG+ + GE W R +S+ + V + A AR D Sbjct: 132 LGDGLLMSAGEKWNHHRRLLTPAFHFDILKSY-VKIFNKSVNTMHAKWQRLTAKGSARLD 190 Query: 567 LHDVLLRLMFDMTCNLVFGVDPGCLQIGLPSLPLARAMDDVLETLFLRHVIPPACWRLMY 746 + + + + D +F D C + S +A ++ L +L ++ P + Sbjct: 191 MFEHISLMTLDSLQKCIFSFDSNCQESN--SEYIAAILE--LSSLIVKRQRQPFLYLDFL 246 Query: 747 RYGFGPEKKMAVARRIIDRFAADTIVKRRYS-------GHKLRGEGITESSDILSFFICN 905 Y ++ A ++ F D +++ R S L+ T++ D + + Sbjct: 247 YYLTADGRRFRKACDVVHNFT-DAVIRERRSTLNTQGVDEFLKARAKTKTLDFIDVLLLA 305 Query: 906 DDASEH----SDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAA 1073 D EH SD +R A +F G DTT + LSW Y L +P ++ E+ + Sbjct: 306 KD--EHGKGLSDVDIRAEADTFMFGGHDTTASALSWILYNLARHPEYQERCRQEVRELLR 363 Query: 1074 RKKVDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKI 1253 ++ ++ ++ +L+ + +L + E LRL+P V + + + + VLP G I G+ Sbjct: 364 DREPEE---IEWDDLAQLPFLTMCIKESLRLHPPVLLISRCCSQDIVLPDGRVIPKGNIC 420 Query: 1254 LVYSYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQ 1433 ++ + + VW D ++P R+ D + + P FI F+AGPR C+G+ A ++ Sbjct: 421 VISIFGVHHNPSVW-PDPEVYNPFRF--DPENPQKRSPLAFIPFSAGPRNCIGQTFAMSE 477 Query: 1434 MKTVAATVLWNFTLETVPGHTVKPKLSIVLHMKNGLAVTVKRRNFFTAK 1580 +K A L F + + K ++L + GL + V+ + T++ Sbjct: 478 IKVALALTLLRFCV-LPDDKEPRRKPELILRAEGGLWLRVEPLSTVTSQ 525
>Q91WL5:CP4AC_MOUSE Cytochrome P450 4A12 - Mus musculus (Mouse)| Length = 508 Score = 100 bits (249), Expect = 2e-20 Identities = 102/411 (24%), Positives = 167/411 (40%), Gaps = 20/411 (4%) Frame = +3 Query: 387 LGDGIFNADGESWRRQRAKSQLIMASPRFR-----------SFSARCTRDKVERSLLPFL 533 +G G+ DG++W + R M +P F + S R DK E+ + Sbjct: 125 IGRGLLLLDGQTWFQHRR-----MLTPAFHYDILKPYTEIMADSVRVMLDKWEQIV---- 175 Query: 534 AHAADVGARCDLHDVLLRLMFDMTCNLVFGVDPGCLQIGLPSLPLARAMDDVLETLF--L 707 D H L+ L M C G +Q+ +A++D+ + +F + Sbjct: 176 --GQDSTLEIFRHITLMTLDTIMKCAFSH---EGSVQLDRKYKSYIQAVEDLNDLVFSRV 230 Query: 708 RHVIPPACWRLMYRYGFGPEKKMAVARRIIDRFAADTIVKRRYSG-------HKLRGEGI 866 R++ ++YR K + + D D ++K R KL+ + Sbjct: 231 RNIFHQN--DIIYRVSSNGCKANSACKLAHDH--TDQVIKSRRIQLQDEEELEKLKKKRR 286 Query: 867 TESSDILSFFICNDDASEHSDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMI 1046 + DIL F ++ SD+ LR +F G DTT + +SW FY L NP +Q Sbjct: 287 LDFLDIL-LFARMENGKSLSDKDLRAEVDTFMFEGHDTTASGISWIFYALATNPEHQQRC 345 Query: 1047 LDELAPIAARKKVDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSG 1226 E+ + + D + ++L M Y + E LR+YP VP + + P G Sbjct: 346 RKEIQSL-----LGDGTSITWNDLDKMPYTTMCIKEALRIYPPVPSVSRELSSPVTFPDG 400 Query: 1227 HEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTC 1406 + G +++ Y + VW + F P R+ G RH + F+ F+ G R C Sbjct: 401 RSLPKGIHVMLSFYGLHHNPTVWPNPEV-FDPSRFAP--GSSRHS--HSFLPFSGGARNC 455 Query: 1407 LGKEVAFTQMKTVAATVLWNFTLETVPGHTVKPKLSIVLHMKNGLAVTVKR 1559 +GK+ A ++K A L F L P P IVL KNG+ + +K+ Sbjct: 456 IGKQFAMNELKVAVALTLLRFELLPDPTRVPIPIPRIVLKSKNGIHLHLKK 506
>P82712:CCD1P_DROME Probable cytochrome P450 12d1 proximal, mitochondrial precursor -| Drosophila melanogaster (Fruit fly) Length = 521 Score = 100 bits (249), Expect = 2e-20 Identities = 98/395 (24%), Positives = 173/395 (43%), Gaps = 14/395 (3%) Frame = +3 Query: 336 NSINYPRGEEYADIFDVLGDGIFNADGESWRRQRAKSQLIMASPR----FRSFSARCTRD 503 +SI Y R D++ + G+ + E+W + R+ I PR + + + Sbjct: 120 DSIVYFREHVRPDVYGEV-QGLVASQNEAWGKLRSAINPIFMQPRGLRMYYEPLSNINNE 178 Query: 504 KVERSLLPFLAHAADVGARCDLHDVLLRLMFDMTCNLVFGVDPGCLQIGLPS---LPLAR 674 +ER + + + D D + RL+F+ + F G ++ + L L + Sbjct: 179 FIER--IKEIRDPKTLEVPEDFTDEISRLVFESLGLVAFDRQMGLIRKNRDNSDALTLFQ 236 Query: 675 AMDDVLETLFLRHVIPPACWRLMYRYGFGPEKK-----MAVARRIIDRFAADTIVKRRYS 839 D+ F + I P+ W+++ + K+ + VA++++ D + KRR + Sbjct: 237 TSRDIFRLTF-KLDIQPSMWKIISTPTYRKMKRTLNDSLNVAQKMLKE-NQDALEKRRQA 294 Query: 840 GHKLRGEGITESSDILSFFICNDDASEHSDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLC 1019 G K+ + E E + ++++LFAG D T +LS L Sbjct: 295 GEKINSNSMLER------------LMEIDPKVAVIMSLDILFAGVDATATLLSAVLLCLS 342 Query: 1020 ENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAA 1199 ++P + + +EL I K +L+ + M YL A + E LR YP+ T + Sbjct: 343 KHPDKQAKLREELLSIMPTKDS----LLNEENMKDMPYLRAVIKETLRYYPNGLGTMRTC 398 Query: 1200 THNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWITDD--GKLRHQPPYK 1373 NDV+ SG+ + G +L+ S + + E + EF PERW+ D GK P+ Sbjct: 399 -QNDVILSGYRVPKGTTVLLGSNVLMK-EATYYPRPDEFLPERWLRDPETGKKMQVSPFT 456 Query: 1374 FIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLE 1478 F+ F GPR C+GK V +M+T A ++ NF +E Sbjct: 457 FLPFGFGPRMCIGKRVVDLEMETTVAKLIRNFHVE 491
>Q8N118:CP4X1_HUMAN Cytochrome P450 4X1 - Homo sapiens (Human)| Length = 509 Score = 100 bits (248), Expect = 3e-20 Identities = 97/408 (23%), Positives = 171/408 (41%), Gaps = 25/408 (6%) Frame = +3 Query: 384 VLGDGIFNADGESWRRQRA------KSQLIMASPRFRSFSARCTRDKVERSLLPFLAHAA 545 +LG G+ DG W + R ++ A + S + DK E+ + Sbjct: 120 LLGKGLAALDGPKWFQHRRLLTPGFHFNILKAYIEVMAHSVKMMLDKWEK-----ICSTQ 174 Query: 546 DVGARCDLHDVLLRLMFDMTCNLVFGVDPGCLQIGLPSLPLARAMDDVLETLFLRHVIPP 725 D ++++ + + D+ F + C Q P A+A+ ++ + +F R Sbjct: 175 DTSV--EVYEHINSMSLDIIMKCAFSKETNC-QTNSTHDPYAKAIFELSKIIFHR----- 226 Query: 726 ACWRLMYR----YGFGPEK-KMAVARRIIDRFAADTIVKRR----YSGHKLRGEGITESS 878 + L+Y + P+ + R+++++ DTI++ R +G K + Sbjct: 227 -LYSLLYHSDIIFKLSPQGYRFQKLSRVLNQYT-DTIIQERKKSLQAGVKQDNTPKRKYQ 284 Query: 879 DILSFFICNDD--ASEHSDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILD 1052 D L + D S SD + L AG DT A +SW Y L NP ++ + Sbjct: 285 DFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAASISWILYCLALNPEHQERCRE 344 Query: 1053 ELAPIAARKKVDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHE 1232 E+ I + D + +L M Y + E RL P+VP + + P G Sbjct: 345 EVRGI-----LGDGSSITWDQLGEMSYTTMCIKETCRLIPAVPSISRDLSKPLTFPDGCT 399 Query: 1233 IKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLG 1412 + AG +++ + + VW K+ F P R+ ++ RH PY ++ F+AG R C+G Sbjct: 400 LPAGITVVLSIWGLHHNPAVW-KNPKVFDPLRFSQENSDQRH--PYAYLPFSAGSRNCIG 456 Query: 1413 KEVAFTQMKTVAATVLWNFTLE-------TVPGHTV-KPKLSIVLHMK 1532 +E A ++K A +L +F + T P H + KPK + LH+K Sbjct: 457 QEFAMIELKVTIALILLHFRVTPDPTRPLTFPNHFILKPKNGMYLHLK 504
>P20817:CP4AE_RAT Cytochrome P450 4A14 precursor - Rattus norvegicus (Rat)| Length = 507 Score = 100 bits (248), Expect = 3e-20 Identities = 80/316 (25%), Positives = 130/316 (41%), Gaps = 7/316 (2%) Frame = +3 Query: 633 GCLQIGLPSLPLARAMDDVLETLFLRHVIPPACWRLMYRYGFGPEKKMAVARRIIDRFAA 812 G +Q+ + S +A++D+ F R + A + Y + +++ I Sbjct: 203 GSVQLDVNSRSYTKAVEDLNNLTFFR--VRSAFYGNSIIYNMSSDGRLSRRACQIAHEHT 260 Query: 813 DTIVKRRYSG-------HKLRGEGITESSDILSFFICNDDASEHSDEFLRDTAVNLLFAG 971 D ++K R + K R + + DIL F +D SDE LR +F G Sbjct: 261 DGVIKMRKAQLQNEEELQKARKKRHLDFLDIL-LFAKMEDGKSLSDEDLRAEVDTFMFEG 319 Query: 972 RDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAALC 1151 DTT + +SW FY L +P ++ +E+ I + D + L + Y + Sbjct: 320 HDTTASGISWVFYALATHPEHQERCREEVQSI-----LGDGTSVTWDHLDQIPYTTMCIK 374 Query: 1152 ECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERW 1331 E LRLYP VP + + P G I G + Y + W + F P R+ Sbjct: 375 EALRLYPPVPSVSRELSSPVTFPDGRSIPKGITTTILIYGLHHNPSYWPNPKV-FDPSRF 433 Query: 1332 ITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLETVPGHTVKPKL 1511 D + H ++ F+ G R C+GK+ A ++K A L F L P P Sbjct: 434 SPDSPRHSHA----YLPFSGGARNCIGKQFAMNELKVAVALTLLRFELLPDPTRIPVPMA 489 Query: 1512 SIVLHMKNGLAVTVKR 1559 +VL KNG+ + +K+ Sbjct: 490 RLVLKSKNGIHLRLKK 505
>Q9VXY0:CP4S3_DROME Probable cytochrome P450 4s3 - Drosophila melanogaster (Fruit fly)| Length = 495 Score = 99.8 bits (247), Expect = 3e-20 Identities = 104/446 (23%), Positives = 187/446 (41%), Gaps = 25/446 (5%) Frame = +3 Query: 303 DPSNVRHIFISNSINYPRGEEYADIFDVLGDGIFNADGESWRRQRAKSQLIMASPRFRSF 482 DP +++ + +N + + Y + LG G+ GESW R+R +L+ FR Sbjct: 81 DPEDIKQLLGNNQL-LTKSRNYELLEPWLGKGLLTNGGESWHRRR---KLLTPGFHFRIL 136 Query: 483 SARCTRDKVE---RSLLPFLAHAADVGARCDLHDVLLRLMFDMTCNLVFGVDPGC-LQIG 650 S ++ +E R L+ L A+ G D++ + D C G+ LQ Sbjct: 137 SE--FKEPMEENCRILVRRLRTKAN-GESFDIYPYITLFALDAICETAMGIKKHAQLQSD 193 Query: 651 LPSLPLARAMDDVLE----------TLFLRHVIPPACWRLMYRYGFGPEKKMAV------ 782 + +++ V+ +F +H P G E++ A+ Sbjct: 194 SEYVQAVQSICRVMHKQSFSFWQRLNVFFKHTKP------------GKEREAALKVLHDE 241 Query: 783 ARRIIDRFAADTIVKRRYSGHKLRGEGITESSDILSFFIC-----NDDASEHSDEFLRDT 947 R+I R + +++ R + + L+F + +E SD +R+ Sbjct: 242 TNRVI-RLRREQLIQERNEWKPEAEQDDVGAKRRLAFLDMLLLTQMEGGAELSDTDIREE 300 Query: 948 AVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSM 1127 +F G DTT + +++ LL +NP V+Q +E + + R+K SM Sbjct: 301 VDTFMFEGHDTTSSAIAFALSLLSKNPDVQQRAFEEASELEGREK------------ESM 348 Query: 1128 VYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDC 1307 YL A + E LR+YPSVP + D+ + G I Y + R + D Sbjct: 349 PYLEAVIKETLRIYPSVPFFSRKVLE-DLEVGKLTVPKGASISCLIYMLHRDPKNF-PDP 406 Query: 1308 MEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLETVP 1487 F P+R++ ++ ++ P+ F AF+AGPR C+G++ A ++KT A +L ++ Sbjct: 407 ERFDPDRFLVNEKQMH---PFAFAAFSAGPRNCIGQKFAMLELKTSLAMLLRSYRFLPDK 463 Query: 1488 GHTVKPKLSIVLHMKNGLAVTVKRRN 1565 H KP +V NG+ + + R+ Sbjct: 464 DHQPKPLAELVTKSGNGIRLRILPRD 489
>Q27589:CP4D2_DROME Cytochrome P450 4d2 - Drosophila melanogaster (Fruit fly)| Length = 501 Score = 99.4 bits (246), Expect = 4e-20 Identities = 103/435 (23%), Positives = 192/435 (44%), Gaps = 15/435 (3%) Frame = +3 Query: 303 DPSNVRHIFISNSINYPRGEEYADIFDVLGDGIFNADGESWRRQRAKSQLIMASPRFRSF 482 DP ++ + +S+ + + Y + LGDG+ + G W +R ++I + F+ Sbjct: 83 DPRDIEFV-LSSQQHITKNNLYKLLNCWLGDGLLMSTGRKWHGRR---KIITPTFHFKIL 138 Query: 483 SARCTR-DKVERSLLPFLAHAADVGARCDLHDVLLRLMFDMTCNLVFGVDPGCLQIGLPS 659 D+ ++ L AD ++ V+ D+ G + P+ Sbjct: 139 EQFVEIFDQQSAVMVEQLQSRADGKTPINIFPVICLTALDIIAETAMGTKINAQKN--PN 196 Query: 660 LPLARAMDDVLETLFLR--HVIPPACWRLMYRYGFGPE-KKMAVARRIIDRFAADTIVKR 830 LP +A++DV L R H W ++R E K+ A +++ F + I +R Sbjct: 197 LPYVQAVNDVTNILIKRFIHAWQRVDW--IFRLTQPTEAKRQDKAIKVMHDFTENIIRER 254 Query: 831 RYS----------GHKLRGEGITESSDILSFFICND-DASEHSDEFLRDTAVNLLFAGRD 977 R + ++ G +L + + D + SDE +R+ +F G D Sbjct: 255 RETLVNNSKETTPEEEVNFLGQKRRMALLDVLLQSTIDGAPLSDEDIREEVDTFMFEGHD 314 Query: 978 TTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAALCEC 1157 TT + +S+ Y + +P V+Q + E+ + + + + D EL ++ + E Sbjct: 315 TTTSAISFCLYEISRHPEVQQRLQQEIRDVLGEDRKSPVTLRDLGELK---FMENVIKES 371 Query: 1158 LRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWIT 1337 LRL+P VP+ + DV G I AG + + + R + + + EF PER+ Sbjct: 372 LRLHPPVPMIGRWFA-EDVEIRGKHIPAGTNFTMGIFVLLR-DPEYFESPDEFRPERFDA 429 Query: 1338 DDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLETVPGHTVKPKLSI 1517 D ++ PY +I F+AGPR C+G++ A +MK+ + +L +F L + G + ++I Sbjct: 430 DVPQIH---PYAYIPFSAGPRNCIGQKFAMLEMKSTVSKLLRHFELLPL-GPEPRHSMNI 485 Query: 1518 VLHMKNGLAVTVKRR 1562 VL NG+ + +K R Sbjct: 486 VLRSANGVHLGLKPR 500
>O48923:C71DA_SOYBN Cytochrome P450 71D10 - Glycine max (Soybean)| Length = 510 Score = 99.4 bits (246), Expect = 4e-20 Identities = 108/512 (21%), Positives = 221/512 (43%), Gaps = 15/512 (2%) Frame = +3 Query: 75 YWFVGLVCCFLSYYRRLQSKKTTKEE-------PTEWPLLGHLLSTLANVSNLHDWATGV 233 Y+ ++ F +++ +Q + P PL+G++ + ++ +H + + Sbjct: 14 YFITSILFIFFVFFKLVQRSDSKTSSTCKLPPGPRTLPLIGNIHQIVGSLP-VHYYLKNL 72 Query: 234 LATTRYNFAAHMGLTGVRFFLTCDPSNVRHIFISNSINYPRGEEY--ADIFDVLGDGI-F 404 +Y H+ L V + P + I ++ +N+ ++ + I G GI F Sbjct: 73 --ADKYGPLMHLKLGEVSNIIVTSPEMAQEIMKTHDLNFSDRPDFVLSRIVSYNGSGIVF 130 Query: 405 NADGESWRRQRAKSQL-IMASPRFRSFSARCTRDKVERSLLPFLAHAA--DVGARCDLHD 575 + G+ WR+ R + ++ + R +SF R R++ L+ +A A + G+ +L Sbjct: 131 SQHGDYWRQLRKICTVELLTAKRVQSF--RSIREEEVAELVKKIAATASEEGGSIFNLTQ 188 Query: 576 VLLRLMFDMTCNLVFGVDPGCLQIGLPSLPLARAMDDVLETLFLRHVIPPA-CWRLMYRY 752 + + F + FG Q+ + ++ + L + + P + +++M Sbjct: 189 SIYSMTFGIAARAAFGKKSRYQQVFISNMHKQLML---LGGFSVADLYPSSRVFQMM--- 242 Query: 753 GFGPEKKMAVARRIIDRFAADTIVKRRYSGHKLRG-EGITESSDILSFFICNDDASEHSD 929 G K+ R+ DR D I + + E + + D+L F + +D Sbjct: 243 --GATGKLEKVHRVTDRVLQDIIDEHKNRNRSSEEREAVEDLVDVLLKFQ-KESEFRLTD 299 Query: 930 EFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDA 1109 + ++ ++ G +T+ +V+ W L NPRV E A R+ D +D Sbjct: 300 DNIKAVIQDIFIGGGETSSSVVEWGMSELIRNPRVM-----EEAQAEVRRVYDSKGYVDE 354 Query: 1110 SELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEG 1289 +EL ++YL + + E +RL+P VP+ + +G+EI + +I++ ++++GR Sbjct: 355 TELHQLIYLKSIIKETMRLHPPVPLLVPRVSRERCQINGYEIPSKTRIIINAWAIGRNPK 414 Query: 1290 VWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNF 1469 WG + F PER++ R ++FI F AG R C G A ++ A +L++F Sbjct: 415 YWG-ETESFKPERFLNSSIDFR-GTDFEFIPFGAGRRICPGITFAIPNIELPLAQLLYHF 472 Query: 1470 TLETVPGHTVKPKLSIVLHMKNGLAVTVKRRN 1565 + +P +L M +T++R+N Sbjct: 473 DWK-LPNKMKNEELD----MTESNGITLRRQN 499
>Q7KR10:CCD1D_DROME Probable cytochrome P450 12d1 distal, mitochondrial precursor -| Drosophila melanogaster (Fruit fly) Length = 521 Score = 99.0 bits (245), Expect = 6e-20 Identities = 97/395 (24%), Positives = 173/395 (43%), Gaps = 14/395 (3%) Frame = +3 Query: 336 NSINYPRGEEYADIFDVLGDGIFNADGESWRRQRAKSQLIMASPR----FRSFSARCTRD 503 +SI Y R D++ + G+ + E+W + R+ I PR + + + Sbjct: 120 DSIVYFREHVRPDVYGEV-QGLVASQNEAWGKLRSAINPIFMQPRGLRMYYEPLSNINNE 178 Query: 504 KVERSLLPFLAHAADVGARCDLHDVLLRLMFDMTCNLVFGVDPGCLQIGLPS---LPLAR 674 +ER + + + D D + RL+F+ + F G ++ + L L + Sbjct: 179 FIER--IKEIRDPKTLEVPEDFTDEISRLVFESLGLVAFDRQMGLIRKNRDNSDALTLFQ 236 Query: 675 AMDDVLETLFLRHVIPPACWRLMYRYGFGPEKK-----MAVARRIIDRFAADTIVKRRYS 839 D+ F + I P+ W+++ + K+ + V+++++ D + KRR + Sbjct: 237 TSRDIFRLTF-KLDIQPSMWKIISTPTYRKMKRTLNDSLNVSQKMLKE-NQDALEKRRQA 294 Query: 840 GHKLRGEGITESSDILSFFICNDDASEHSDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLC 1019 G K+ + E E + ++++LFAG D T +LS L Sbjct: 295 GEKINSNSMLER------------LMEIDPKVAVIMSLDILFAGVDATATLLSAVLLCLS 342 Query: 1020 ENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAA 1199 ++P + + +EL I K +L+ + M YL A + E LR YP+ T + Sbjct: 343 KHPDKQAKLREELLSIMPTKDS----LLNEENMKDMPYLRAVIKETLRYYPNGFGTMRTC 398 Query: 1200 THNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWITDD--GKLRHQPPYK 1373 NDV+ SG+ + G +L+ S + + E + EF PERW+ D GK P+ Sbjct: 399 -QNDVILSGYRVPKGTTVLLGSNVLMK-EATYYPRPDEFLPERWLRDPETGKKMQVSPFT 456 Query: 1374 FIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLE 1478 F+ F GPR C+GK V +M+T A ++ NF +E Sbjct: 457 FLPFGFGPRMCIGKRVVDLEMETTVAKLIRNFHVE 491
>Q27517:C13A3_CAEEL Putative cytochrome P450 CYP13A3 - Caenorhabditis elegans| Length = 520 Score = 99.0 bits (245), Expect = 6e-20 Identities = 104/427 (24%), Positives = 170/427 (39%), Gaps = 34/427 (7%) Frame = +3 Query: 303 DPSNVRHIFISNSINYPRGEEYADIFDVLGDG---IFNADGESWRRQRAKSQLIMASPRF 473 DP V +F+ N+ ++ D D + + G W+R R +ASP F Sbjct: 82 DPEFVHEVFVKQFDNFYARKQNPLQGDPDKDPRIHLVTSQGHRWKRLRT-----LASPTF 136 Query: 474 RSFSARCTRDKVERSLLPFLAH---AADVGARCDLHDVLLRLMFDMTCNLVFGVDPGCLQ 644 + S R VE S+ + H G D+ + D+ + G G + Sbjct: 137 SNKSLRKIFSTVEESVAEMMRHLEKGTAGGKTIDILEYYQEFTMDIIGKIAMG-QSGSMM 195 Query: 645 IGLPSLPLARAMDDVL-ETLFLRHVIPPACWRLMYRYGFG--PEKKMAVARRIIDRFAAD 815 P L RA+ + +F+ I P + +R+ F P + + A Sbjct: 196 FENPWLDKIRAIFNTRGNIIFIICGIVPFTGSI-FRWFFSKVPTAQTVTSLMHTLEIALT 254 Query: 816 TIVKRRYSGHKLRGEGITESSDILSFFICNDDASEHSDEFLRDTAVN------------- 956 V++R + K E E D + F+ D +D FL D N Sbjct: 255 KRVEQRAADEKAGIESSGEPQDFIDLFL---DVQADTD-FLEDETKNGFARSQIVKVDKH 310 Query: 957 ------------LLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVV 1100 L AG DTT LS+ YLL +P +++ + +E+ R+ D V Sbjct: 311 LTFDEIIGQLFVFLLAGYDTTALSLSYSSYLLARHPEIQKKLQEEVD----RECPDPEVT 366 Query: 1101 LDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGR 1280 D +LS + Y+ + E LRLYP I H G +I+ G + ++++ Sbjct: 367 FD--QLSKLKYMECVIKETLRLYPLASIVHNRKCMKSTTVLGMKIEEGTNVQADTWTLHY 424 Query: 1281 MEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVL 1460 WG++ EF PERW + D + + Y + F GPR C+G +A+ + K + A +L Sbjct: 425 DPKFWGENANEFKPERWESGDEQAVAKGAY--LPFGLGPRICIGMRLAYMEEKMLLAQIL 482 Query: 1461 WNFTLET 1481 ++LET Sbjct: 483 KKYSLET 489
>Q9V557:CP4P2_DROME Probable cytochrome P450 4p2 - Drosophila melanogaster (Fruit fly)| Length = 520 Score = 98.6 bits (244), Expect = 8e-20 Identities = 117/522 (22%), Positives = 210/522 (40%), Gaps = 23/522 (4%) Frame = +3 Query: 69 HWYWFVGLVCCFLSYYRRLQSKKTTKEEPTEWPLLGHLLSTLANVSNLHDWATGVLATTR 248 HW + V L+++ R K K + P++ + AN +L T + T Sbjct: 17 HWIYKVNKDYNILAFFARRVQTKDGKPLDSLVPMIKGR-TVFANCFDLLGKDTDQVFTHL 75 Query: 249 YNFAAHMGLTGVRFFLTCDPSNVRHIF-ISNSINYP----RGEEYADIFDVLGDGIFNAD 413 A + G + +++ + NV +N +N+P +G Y + L G+ A Sbjct: 76 RQLAKNSGDSYLQYSMGFSNFNVIDAHNAANILNHPNLITKGVIYNFLHPFLRTGVLTAT 135 Query: 414 GESWRRQRAKSQLIMASPRFRSFSARCTRDKVERSLLPFLAHAADVGARCD----LHDVL 581 + W +R S R+F E + L + + + L D + Sbjct: 136 EKKWHTRR--------SMLTRTFHLDILNQFQEIFIAESLKFVSQFQGQNEVVVSLKDRI 187 Query: 582 LRLMFDMTCNLVFGVDPGCLQIGLPSLPLARAMDDVLETLFLRHVIPPACWRLMYRYGFG 761 R + C G+ L RA +++ R ++ P W Y Sbjct: 188 SRFTLNSICETAMGIK---LDEMAEKGDRYRANFHIIDEGLTRRIVNPLYWDDCV-YNMF 243 Query: 762 PEKKMAVARRIIDRFAADTIVKRRYS-GHKLRGEGITESSD------------ILSFFIC 902 K A +++ F+ + I KRR +L T+++D +L IC Sbjct: 244 TGHKYNAALKVVHEFSREIIAKRRVLLEEELENRRATQTADDDICVIRKKRFAMLDTLIC 303 Query: 903 NDDASEHSDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKK 1082 + D + + L+ G DTT L + + +++ E+ Sbjct: 304 AEKDGLIDDIGISEEVDTLMAEGYDTTSIGLVFGLMNMSLYAAEQELCYQEIQ----EHI 359 Query: 1083 VDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVY 1262 +DD+ L+ S+LS + YL + E +RLYPS+PI + L +G + +I ++ Sbjct: 360 LDDLSNLNLSQLSKLNYLGYFIKETMRLYPSIPIMGRQTLQETELENGLILPKRSQINIH 419 Query: 1263 SYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKT 1442 + + R W + EF PER++ + RH PY +I F+AG R C+G++ A +MKT Sbjct: 420 VFDIHRNPKYW-ESPEEFRPERFLPQNCLKRH--PYAYIPFSAGQRNCIGQKYAMQEMKT 476 Query: 1443 VAATVLWNF-TLETVPGHTVKPKLSIVLHMKNGLAVTVKRRN 1565 + +L +F L + ++ ++ I L KN + V + RRN Sbjct: 477 LMVVILKHFKILPVIDPKSIVFQVGITLRFKNKIKVKLVRRN 518
>Q27513:C13A4_CAEEL Putative cytochrome P450 CYP13A4 - Caenorhabditis elegans| Length = 520 Score = 98.6 bits (244), Expect = 8e-20 Identities = 102/386 (26%), Positives = 158/386 (40%), Gaps = 28/386 (7%) Frame = +3 Query: 408 ADGESWRRQRAKSQLIMASPRFRSFSARCTRDKVERSLLPFLAHAADVGAR---CDLHDV 578 A G W+R R +ASP F + S R VE +++ + H + A+ DL D Sbjct: 120 AQGHRWKRLRT-----LASPTFSNKSLRKIMSTVEETVVELMRHLDEASAKGKAVDLLDY 174 Query: 579 LLRLMFDMTCNLVFGVDPGCLQIGLPSLPLARAMDDVLETL-FLRHVIPPACWRLMYRYG 755 D+ + G L P LP + + + FL + P LM R Sbjct: 175 YQEFTLDIIGRIAMGQTES-LMFRNPMLPKVKEIFKKGGKMPFLIAGVFPIAGTLM-RQL 232 Query: 756 FGPEKKMAVARRIIDRF--AADTIVKRRYSGHKLRGEGITESSDILSFFI---CNDDASE 920 F K + A I++ A + +++R + K E E D + F+ N D E Sbjct: 233 FMKFPKFSPAFGIMNTMEKALNKRLEQRAADKKAGIEPSGEPQDFIDLFLDARANVDFIE 292 Query: 921 HS-------------------DEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQM 1043 DE + V LL AG DTT LS+ YLL +P +++ Sbjct: 293 EESTLGFAKSEVLKVDKHLTFDEIIGQLFVFLL-AGYDTTALSLSYSSYLLATHPEIQKK 351 Query: 1044 ILDELAPIAARKKVDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPS 1223 + +E+ R+ D V D ++S + Y+ + E LR+YP + H Sbjct: 352 LQEEVD----RECPDPEVTFD--QISKLKYMECVVKEALRMYPLASLVHNRKCMKKTNVL 405 Query: 1224 GHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRT 1403 G EI G + V ++++ VWG D EF PERW T D + Y + F GPR Sbjct: 406 GVEIDEGTNVQVDTWTLHYDPKVWGDDASEFKPERWETGDELFYAKGGY--LPFGMGPRI 463 Query: 1404 CLGKEVAFTQMKTVAATVLWNFTLET 1481 C+G +A + K + +L +T +T Sbjct: 464 CIGMRLAMMEEKLLLTHILKKYTFDT 489
>Q8SPK0:CP4AP_PIG Cytochrome P450 4A25 - Sus scrofa (Pig)| Length = 504 Score = 98.2 bits (243), Expect = 1e-19 Identities = 64/212 (30%), Positives = 94/212 (44%) Frame = +3 Query: 924 SDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVL 1103 SD LR +F G DTT + +SW Y L +P +Q +E+ + + D + Sbjct: 301 SDTDLRAEVDTFMFEGHDTTASGISWILYALASHPEHQQRCREEIQGL-----LGDGTSI 355 Query: 1104 DASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRM 1283 L M Y + E LRLYP VP + + P G + AG + + YS+ Sbjct: 356 TWDHLDQMPYTTMCIKEALRLYPPVPGVSRELSKPITFPDGRSLPAGIILSLSVYSLHHN 415 Query: 1284 EGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLW 1463 VW EF P R+ G RH + F+ F+ G R C+GK+ A +MK A L Sbjct: 416 PQVWPNP-EEFDPSRFAP--GSARHS--HAFMPFSGGSRNCIGKQFAMNEMKVAVALTLL 470 Query: 1464 NFTLETVPGHTVKPKLSIVLHMKNGLAVTVKR 1559 F L P +VLH KNG+ + +++ Sbjct: 471 RFELAPDPSRKPTVIPEVVLHSKNGIHLKLRK 502
>Q9GJX5:CP4AL_PIG Cytochrome P450 4A21 - Sus scrofa (Pig)| Length = 504 Score = 98.2 bits (243), Expect = 1e-19 Identities = 68/227 (29%), Positives = 101/227 (44%) Frame = +3 Query: 879 DILSFFICNDDASEHSDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDEL 1058 DIL F ++ + SD +R + AG D+T + +SW Y L NP +Q +E+ Sbjct: 287 DIL-LFARMENGNSLSDTDVRAEVDTFMAAGHDSTASGISWVLYALASNPEHQQRCREEI 345 Query: 1059 APIAARKKVDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIK 1238 + + D + L M Y + E LRLYP VP + + P G + Sbjct: 346 QGL-----LGDGTSITWDHLDQMPYTTMCIKEALRLYPPVPSVGRELSKPITFPDGRSLP 400 Query: 1239 AGDKILVYSYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKE 1418 AG + + Y + VW EF P R+ G RH + F+ F+ G R C+GK+ Sbjct: 401 AGIILSLSIYGLHHNPQVWPNP-EEFDPSRFAP--GSARHS--HAFMPFSGGSRNCIGKQ 455 Query: 1419 VAFTQMKTVAATVLWNFTLETVPGHTVKPKLSIVLHMKNGLAVTVKR 1559 A +MK V A L F L P P IVL KNG+ + +++ Sbjct: 456 FAMNEMKVVVALTLLRFELAPDPSRIPVPIQGIVLKSKNGIHLNLRK 502
>P63719:CP139_MYCTU Putative cytochrome P450 139 - Mycobacterium tuberculosis| Length = 430 Score = 98.2 bits (243), Expect = 1e-19 Identities = 81/287 (28%), Positives = 132/287 (45%), Gaps = 7/287 (2%) Frame = +3 Query: 720 PPACWRLMYRYGF-GPEKKMAVARRI---IDRFAADTIVKRRYSGHKLRGEGITESSDIL 887 PP RL R G + MA +RI ID AD R H L + ++ Sbjct: 158 PPQVMRLQQRVNSPGWRRAMAARKRIDDLIDAQIADARTAPRPDDHML--------TTLI 209 Query: 888 SFFICNDDASEHSDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPI 1067 S C+++ + SD +RD+ V+L+ AG +TT L+W Y L P + E+A + Sbjct: 210 SG--CSEEGTTLSDNEIRDSIVSLITAGYETTSGALAWAIYALLTVPGTWESAASEVARV 267 Query: 1068 AARKKVDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGD 1247 + V A +LS++ YL+ + E LRLY I+ + D+ GH I+AG Sbjct: 268 LGGR------VPAADDLSALTYLNGVVHETLRLYSPGVISARRVL-RDLWFDGHRIRAGR 320 Query: 1248 KILVYSYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAF 1427 ++ +Y R+ +W + EF P RW + R P++FI F+ G C+G +A Sbjct: 321 LLIFSAYVTHRLPEIW-PEPTEFRPLRWDPNAADYRKPAPHEFIPFSGGLHRCIGAVMAT 379 Query: 1428 TQMKTVAATVLWNFTLETVPG---HTVKPKLSIVLHMKNGLAVTVKR 1559 T+M + A ++ L+ +P H ++ L GL V +++ Sbjct: 380 TEMTVILARLVARAMLQ-LPAQRTHRIRAANFAALRPWPGLTVEIRK 425
>P63720:CP139_MYCBO Putative cytochrome P450 139 - Mycobacterium bovis| Length = 430 Score = 98.2 bits (243), Expect = 1e-19 Identities = 81/287 (28%), Positives = 132/287 (45%), Gaps = 7/287 (2%) Frame = +3 Query: 720 PPACWRLMYRYGF-GPEKKMAVARRI---IDRFAADTIVKRRYSGHKLRGEGITESSDIL 887 PP RL R G + MA +RI ID AD R H L + ++ Sbjct: 158 PPQVMRLQQRVNSPGWRRAMAARKRIDDLIDAQIADARTAPRPDDHML--------TTLI 209 Query: 888 SFFICNDDASEHSDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPI 1067 S C+++ + SD +RD+ V+L+ AG +TT L+W Y L P + E+A + Sbjct: 210 SG--CSEEGTTLSDNEIRDSIVSLITAGYETTSGALAWAIYALLTVPGTWESAASEVARV 267 Query: 1068 AARKKVDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGD 1247 + V A +LS++ YL+ + E LRLY I+ + D+ GH I+AG Sbjct: 268 LGGR------VPAADDLSALTYLNGVVHETLRLYSPGVISARRVL-RDLWFDGHRIRAGR 320 Query: 1248 KILVYSYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAF 1427 ++ +Y R+ +W + EF P RW + R P++FI F+ G C+G +A Sbjct: 321 LLIFSAYVTHRLPEIW-PEPTEFRPLRWDPNAADYRKPAPHEFIPFSGGLHRCIGAVMAT 379 Query: 1428 TQMKTVAATVLWNFTLETVPG---HTVKPKLSIVLHMKNGLAVTVKR 1559 T+M + A ++ L+ +P H ++ L GL V +++ Sbjct: 380 TEMTVILARLVARAMLQ-LPAQRTHRIRAANFAALRPWPGLTVEIRK 425
>P29980:CPXN_ANASP Probable cytochrome P450 110 - Anabaena sp. (strain PCC 7120)| Length = 459 Score = 97.8 bits (242), Expect = 1e-19 Identities = 101/425 (23%), Positives = 186/425 (43%), Gaps = 15/425 (3%) Frame = +3 Query: 246 RYNFAAHMGLTGV-RFFLTCDPSNVRHIFISNS-INYPRGEEYADIFDVLG-DGIFNADG 416 +Y M L G+ F + +P ++ IF +S + RG A+ ++G + DG Sbjct: 34 KYGNIFSMQLAGIGSFVILGEPQALQEIFTQDSRFDVGRGNTLAE--PLIGRTSLMLMDG 91 Query: 417 ESWRRQRAKSQLIMASPRFRSFSARCTRDKVERSLLPFLAHAADVGARCDLHDVLLRLMF 596 + RR+R R ++++ + + +A +G + +L Sbjct: 92 DRHRRERKLLMPPFHGERLQAYAQQICL------ITNQIASEWQIGQPFVARSAMQKLSL 145 Query: 597 DMTCNLVFGVDPGCLQ----------IGLPSLPLARAMDDVLETLFLRHVIPPACWRLMY 746 ++ +VFG+ G + + PL +M LFL+ + W Sbjct: 146 EVIIQIVFGLADGERYQQIKPLFTDWLNMTDSPLRSSM------LFLKSLQKD--WGTWT 197 Query: 747 RYGFGPEKKMAVARRIIDRFAADTIVKRRYSGHKLRGEGITESSDILSFFIC--NDDASE 920 +G K+ R I D A+ I ++R ++ RG D+LS + +++ Sbjct: 198 PWGQMKHKQ----RSIYDLLQAE-IEEKRTKENEQRG-------DVLSLMMAARDENGQA 245 Query: 921 HSDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVV 1100 +DE L+D + +LFAG +TT ++W FY + +N V++ + EL + A Sbjct: 246 MTDEELKDELLTILFAGHETTATTIAWAFYQILKNVNVQEKLQQELDRLGANP------- 298 Query: 1101 LDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGR 1280 + E++ + YL A E LR+YP +P T + + +G++++ ++ Y + Sbjct: 299 -NPMEIAQLPYLTAVSQETLRMYPVLPTLFPRITKSSINIAGYQLEPDTTLMASIYLIHY 357 Query: 1281 MEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVL 1460 E ++ + +F PER+I R P ++I F G R CLG +A ++K V ATVL Sbjct: 358 REDLY-PNPQQFRPERFIE-----RQYSPSEYIPFGGGSRRCLGYALALLEIKLVIATVL 411 Query: 1461 WNFTL 1475 N+ L Sbjct: 412 SNYQL 416
>Q9V4T5:CP4E1_DROME Probable cytochrome P450 4e1 - Drosophila melanogaster (Fruit fly)| Length = 531 Score = 97.4 bits (241), Expect = 2e-19 Identities = 95/384 (24%), Positives = 170/384 (44%), Gaps = 17/384 (4%) Frame = +3 Query: 369 ADIFDV----LGDGIFNADGESWRRQRAKSQLIMASPRFRSFSARCTRDKVERSLLPF-- 530 +D++D+ LG G+ + G W + R M +P F + + + + F Sbjct: 102 SDVYDLTHPWLGLGLLTSTGSKWHKHRK-----MITPAFHFNILQDFHEVMNENSTKFID 156 Query: 531 -LAHAADVGARCDLHDVLLRLMFDMTCNLVFGVDPGCLQIGLPSLPLARAMDDVLETLFL 707 L AD G D + L D+ C+ GV ++ S+ +A D+ T+ + Sbjct: 157 QLKKVADGGNIFDFQEEAHYLTLDVICDTAMGVSINAMENRSSSV--VQAFKDITYTIKM 214 Query: 708 RHVIPPACW-RLMYRYGFGPE-KKMAVARRIIDRFAADTIVKR---RYSGHKLRGEGITE 872 R P W R Y + F PE + + + + F + I KR R SG ++ + Sbjct: 215 RAFSP---WKRNKYLFHFAPEYPEYSKTLKTLQDFTNEIIAKRIEVRKSGLEVGIKADEF 271 Query: 873 SSDILSFF----ICNDDASEHSDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQ 1040 S ++F D + + L + +F G DTT + + + YLL +P ++ Sbjct: 272 SRKKMAFLDTLLSSKVDGRPLTSQELYEEVSTFMFEGHDTTTSGVGFAVYLLSRHPDEQE 331 Query: 1041 MILDELAPIAARKKVDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLP 1220 + +E + + E+S+M +L + E RLYPSVP + T D + Sbjct: 332 KLFNEQCDVMGASGLGRDATFQ--EISTMKHLDLFIKEAQRLYPSVPFIGRF-TEKDYVI 388 Query: 1221 SGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQP-PYKFIAFNAGP 1397 G + G + + +G + V+ KD +F PER+ R +P P++++ F+AGP Sbjct: 389 DGDIVPKGTTLNLGLLMLGYNDRVF-KDPHKFQPERFD------REKPGPFEYVPFSAGP 441 Query: 1398 RTCLGKEVAFTQMKTVAATVLWNF 1469 R C+G++ A ++KTV + ++ NF Sbjct: 442 RNCIGQKFALLEIKTVVSKIIRNF 465
>O16805:CP4D1_DROSI Cytochrome P450 4d1 - Drosophila simulans (Fruit fly)| Length = 512 Score = 97.1 bits (240), Expect = 2e-19 Identities = 112/455 (24%), Positives = 195/455 (42%), Gaps = 35/455 (7%) Frame = +3 Query: 303 DPSNVRHIFISNSINYPRGEEYADIFDVLGDGIFNADGESWRRQRAKSQLIMASPRFRSF 482 +P +V + + N GE Y + L +G+ + G W ++R ++I + F+ Sbjct: 88 NPKDVEVVLGTLRFNDKAGE-YKALEPWLKEGLLVSRGRKWHKRR---KIITPAFHFKIL 143 Query: 483 SA------RCTRDKVERSLLPFLAHAADVGARCDLHDVLLRLMFDMTCNLVFGV------ 626 + +RD + L H D G L+D + D C GV Sbjct: 144 DQFVDVFEKGSRDLLRNMEQDRLKHG-DSGF--SLYDWINLCTMDTICETAMGVSINAQS 200 Query: 627 --DPGCLQ-IGLPSLPLARAMDDVLETLFLRHVIPPACWRLMYRYGFGPEKKMAVARRII 797 D +Q + S+ L + M ++L L +++ P EKK A ++ Sbjct: 201 NADSEYVQAVKTISMVLHKRMFNILYRFDLTYMLTPLA---------RAEKK---ALNVL 248 Query: 798 DRFAADTIVKRRYSGHKLRGEGITESS----------------DILSFFICNDDASEHSD 929 +F IV+RR +L EG ++ S DIL ++ + D Sbjct: 249 HQFTEKIIVQRR---EELIREGSSQESSKDDADVGAKRKMAFLDILLQSTVDERPLSNLD 305 Query: 930 EFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDA 1109 +R+ +F G DTT + L +FFY + +P ++ +E+ + D + Sbjct: 306 --IREEVDTFMFEGHDTTSSALMFFFYNIATHPEAQKKCFEEIRSVVGN---DKSTPVSY 360 Query: 1110 SELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEG 1289 L+ + Y+ + E LR+YPSVP+ + D +G I AG I + +GR E Sbjct: 361 ELLNQLHYVDLCVKETLRMYPSVPLLGRKVLE-DCEINGKLIPAGTNIGISPLYLGRREE 419 Query: 1290 VWGKDCMEFSPERW--ITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLW 1463 ++ + F PER+ +T KL PY +I F+AGPR C+G++ A ++K + A VL Sbjct: 420 LFSEP-NSFKPERFDVVTTAEKLN---PYAYIPFSAGPRNCIGQKFAMLEIKAIVANVLR 475 Query: 1464 NFTLETVPGHTVKPKL--SIVLHMKNGLAVTVKRR 1562 ++ ++ V + P L ++L K+ L V+ R Sbjct: 476 HYEVDFVGDSSEPPVLIAELILRTKDPLMFKVRER 510
>O35728:CP4AE_MOUSE Cytochrome P450 4A14 precursor - Mus musculus (Mouse)| Length = 507 Score = 97.1 bits (240), Expect = 2e-19 Identities = 82/316 (25%), Positives = 129/316 (40%), Gaps = 7/316 (2%) Frame = +3 Query: 633 GCLQIGLPSLPLARAMDDVLETLFLRHVIPPACWRLMYRYGFGPEKKMAVARRIIDRFAA 812 G +Q+ S +A++D+ F R + A ++ Y + +++ I Sbjct: 203 GSVQLDENSKLYTKAVEDLNNLTFFR--LRNAFYKYNIIYNMSSDGRLSHHACQIAHEHT 260 Query: 813 DTIVKRRYSG-------HKLRGEGITESSDILSFFICNDDASEHSDEFLRDTAVNLLFAG 971 D ++K R S K R + + DIL F +D + SDE LR +F G Sbjct: 261 DGVIKMRKSQLQNEEELQKARKKRHLDFLDIL-LFARMEDRNSLSDEDLRAEVDTFMFEG 319 Query: 972 RDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAALC 1151 DTT + +SW FY L +P +Q +E+ I + D + L M Y + Sbjct: 320 HDTTASGISWIFYALATHPEHQQRCREEVQSI-----LGDGTSVTWDHLGQMPYTTMCIK 374 Query: 1152 ECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERW 1331 E LRLYP V + + P G I G + Y + W + F P R+ Sbjct: 375 EALRLYPPVISVSRELSSPVTFPDGRSIPKGITATISIYGLHHNPRFWPNPKV-FDPSRF 433 Query: 1332 ITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLETVPGHTVKPKL 1511 D H ++ F+ G R C+GK+ A ++K A L F L P P Sbjct: 434 APDSSHHSHA----YLPFSGGSRNCIGKQFAMNELKVAVALTLLRFELLPDPTRIPVPIA 489 Query: 1512 SIVLHMKNGLAVTVKR 1559 +VL KNG+ + +K+ Sbjct: 490 RLVLKSKNGIHLCLKK 505
>Q27516:C13A8_CAEEL Putative cytochrome P450 CYP13A8 - Caenorhabditis elegans| Length = 509 Score = 96.7 bits (239), Expect = 3e-19 Identities = 76/285 (26%), Positives = 127/285 (44%), Gaps = 21/285 (7%) Frame = +3 Query: 792 IIDRFAADTIVKR--RYSGHKLRGEGITESSDILSFFICNDDASEH----SDEFLRDTAV 953 ++ + D ++ R + K G E++D + F+ EH +DEF + ++ Sbjct: 241 VVQKSVTDAVMSRIAQREADKKHGVEPGEAADYIDMFLNARAEVEHFGESNDEFHKSSSY 300 Query: 954 N---------------LLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVD 1088 N L AG DTT LS+ Y L NP+++ + DE+ ++ + Sbjct: 301 NNRQLTTQEIISQCFVFLVAGFDTTAISLSYVTYFLALNPKIQSKLQDEVD----KECPN 356 Query: 1089 DMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSY 1268 D + D +LS + Y+ + E LRL+P + + + ++AG +++ ++ Sbjct: 357 DEITFD--QLSKLKYMDNVIKESLRLFPFASFANSRRCMRNTVIGEQIVEAGVDVMIDTW 414 Query: 1269 SMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVA 1448 ++ + VWG D EF PERW D L Q Y ++F AGPR CLG A + K + Sbjct: 415 TLHHDKNVWGNDVEEFKPERW---DSPLTPQQAY--LSFGAGPRVCLGMRFALLEQKGLL 469 Query: 1449 ATVLWNFTLETVPGHTVKPKLSIVLHMKNGLAVTVKRRNFFTAKP 1583 + +L +T ET K +L I L G A F + KP Sbjct: 470 SHILKKYTFET----NAKTQLPIKL---VGRATARPENLFLSLKP 507
>Q12587:CP52Q_CANMA Cytochrome P450 52C2 - Candida maltosa (Yeast)| Length = 510 Score = 96.3 bits (238), Expect = 4e-19 Identities = 105/443 (23%), Positives = 181/443 (40%), Gaps = 27/443 (6%) Frame = +3 Query: 273 LTGVRFFLTCDPSNVRHIFISNSI-NYPRGEEYADIFDVLGDGIFNADGESWRRQRAKSQ 449 LTG + +T +P N R + S + ++ G + +LGDGIF+++GESW+ R + Sbjct: 86 LTGSQI-VTMEPENERTMCSSAHMKDWTIGYRPFALKPLLGDGIFSSEGESWKHSRIMLR 144 Query: 450 LIMASPRFRSFSARCTRDKVERSLLPFLAHAADVGARCDLHDVLLRLMFDMTCNLVFGVD 629 I A + +A + L+ + ++ DL + D + +FG Sbjct: 145 PIFAKEHIKQITAM---EPYMLLLIEIIKSSSANEGPVDLQPLFHAFTIDYASDFLFGES 201 Query: 630 PGCLQIGLPSLP-----------LARAMDDVLETLFLRHVIPPACWRLMYRYGFGPEKKM 776 L+ L A +DV L R ++ P + + + KK Sbjct: 202 CDVLKENLGGKSTSGMDAQVKRDFASVFNDVQNYLTKRMMLGPLAFLVSSKDFHDGIKKQ 261 Query: 777 AVARRIIDRFAADTIVKRRYSGHKLRGEGITESSDILSFFICNDDASEHSD-EFLRDTAV 953 + F I + E + + S ++ A + D + L+D + Sbjct: 262 ---HEFVSYFVQKAI--------SMSDEELNDESK--NYVFLYQLAKQTKDAKVLQDELL 308 Query: 954 NLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVY 1133 ++L AGR+TT ++LS+ F+ L + V + + + D+ + + + Y Sbjct: 309 SILLAGRNTTASLLSFLFFELSHHENVWTTLKE-----VVDQSFPDVESITFETIQNCDY 363 Query: 1134 LHAALCECLRLYPSVPITHKAATHNDVLPSG------HEI--KAGDKILVYSYSMGRMEG 1289 L L E LR+ PSVP + A + +LP G H I K GD++L Y+ R E Sbjct: 364 LRWCLFESLRVNPSVPFNSRTANKDTILPRGGGEDCSHPILVKKGDQVLFPLYASNRQEK 423 Query: 1290 VWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNF 1469 +G+ EF PERW L F+ F+ GPR CLG++ A + V ++ F Sbjct: 424 YFGRKPEEFIPERW----RDLPKTGGPAFMPFSTGPRMCLGQQFALIEASYVTIRLVQTF 479 Query: 1470 ------TLETVPGHTVKPKLSIV 1520 +LE P V + ++ Sbjct: 480 SKLKSHSLEYAPKRLVAATIRLI 502
>P33269:CP4D1_DROME Cytochrome P450 4d1 - Drosophila melanogaster (Fruit fly)| Length = 512 Score = 96.3 bits (238), Expect = 4e-19 Identities = 110/455 (24%), Positives = 193/455 (42%), Gaps = 35/455 (7%) Frame = +3 Query: 303 DPSNVRHIFISNSINYPRGEEYADIFDVLGDGIFNADGESWRRQRAKSQLIMASPRFRSF 482 +P +V + + N GE Y + L +G+ + G W ++R ++I + F+ Sbjct: 88 NPKDVEVVLGTLRFNDKAGE-YKALEPWLKEGLLVSRGRKWHKRR---KIITPAFHFKIL 143 Query: 483 SA------RCTRDKVERSLLPFLAHAADVGARCDLHDVLLRLMFDMTCNLVFGV------ 626 + +RD + L H + L+D + D C GV Sbjct: 144 DQFVEVFEKGSRDLLRNMEQDRLKHGE---SGFSLYDWINLCTMDTICETAMGVSINAQS 200 Query: 627 --DPGCLQ-IGLPSLPLARAMDDVLETLFLRHVIPPACWRLMYRYGFGPEKKMAVARRII 797 D +Q + S+ L + M ++L L +++ P EKK A ++ Sbjct: 201 NADSEYVQAVKTISMVLHKRMFNILYRFDLTYMLTPLA---------RAEKK---ALNVL 248 Query: 798 DRFAADTIVKRRYSGHKLRGEGITESS----------------DILSFFICNDDASEHSD 929 +F IV+RR +L EG ++ S DIL ++ + D Sbjct: 249 HQFTEKIIVQRR---EELIREGSSQESSNDDADVGAKRKMAFLDILLQSTVDERPLSNLD 305 Query: 930 EFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDA 1109 +R+ +F G DTT + L +FFY + +P ++ +E+ + D + Sbjct: 306 --IREEVDTFMFEGHDTTSSALMFFFYNIATHPEAQKKCFEEIRSVVGN---DKSTPVSY 360 Query: 1110 SELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEG 1289 L+ + Y+ + E LR+YPSVP+ + D +G I AG I + +GR E Sbjct: 361 ELLNQLHYVDLCVKETLRMYPSVPLLGRKVLE-DCEINGKLIPAGTNIGISPLYLGRREE 419 Query: 1290 VWGKDCMEFSPERW--ITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLW 1463 ++ + F PER+ +T KL PY +I F+AGPR C+G++ A ++K + A VL Sbjct: 420 LFSEP-NSFKPERFDVVTTAEKLN---PYAYIPFSAGPRNCIGQKFAMLEIKAIVANVLR 475 Query: 1464 NFTLETVPGHTVKPKL--SIVLHMKNGLAVTVKRR 1562 ++ ++ V + P L ++L K L V+ R Sbjct: 476 HYEVDFVGDSSEPPVLIAELILRTKEPLMFKVRER 510
>O88833:CP4AA_MOUSE Cytochrome P450 4A10 - Mus musculus (Mouse)| Length = 509 Score = 96.3 bits (238), Expect = 4e-19 Identities = 64/227 (28%), Positives = 103/227 (45%) Frame = +3 Query: 879 DILSFFICNDDASEHSDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDEL 1058 DIL F ++ SD+ LR +F G DTT + +SW FY L +P +Q +E+ Sbjct: 292 DIL-LFARMENGDSMSDKDLRAEVDTFMFEGHDTTASGVSWIFYALATHPDHQQRCREEV 350 Query: 1059 APIAARKKVDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIK 1238 + + D + L + Y + E LRLYP VP + + + P G + Sbjct: 351 QSL-----LGDGSSITWDHLDQIPYTTMCIKEALRLYPPVPGIVRELSTSVTFPDGRSLP 405 Query: 1239 AGDKILVYSYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKE 1418 G ++ + Y + VW + F P R+ D + H F+ F+ G R C+GK+ Sbjct: 406 KGVQVTLSIYGLHHNPKVWPNPEV-FDPSRFAPDSPRHSHS----FLPFSGGARNCIGKQ 460 Query: 1419 VAFTQMKTVAATVLWNFTLETVPGHTVKPKLSIVLHMKNGLAVTVKR 1559 A +++K + A L F L P P +VL KNG+ + +K+ Sbjct: 461 FAMSELKVIVALTLLRFELLPDPTRVPMPLARLVLKSKNGIYLHLKK 507
>Q9VYQ7:CP311_DROME Probable cytochrome P450 311a1 - Drosophila melanogaster (Fruit fly)| Length = 483 Score = 96.3 bits (238), Expect = 4e-19 Identities = 94/406 (23%), Positives = 175/406 (43%), Gaps = 7/406 (1%) Frame = +3 Query: 354 RGEEYADIFDVLGDGIFNADGESWRRQRAKSQLIMASPRFRSFSARCTRDKVERSLLPFL 533 + + + + ++G+G+ + G W RQR RSF A VER + Sbjct: 96 KADTFMQLEPLIGNGLLISHGAHWTRQRRLLTPAFQPQLLRSF-APAIGGHVERLVGRL- 153 Query: 534 AHAADVGARCDLHDVLLRLMFDMTCNLVFGVDPGCLQIGLPSLPLARAMDDVLETLFLRH 713 A GA ++ + L + D + G + P+ +A + LF R Sbjct: 154 --GATRGAFLEVTEPLFACLLDAIVDTSMGAQLDTQSVD--HSPIIQAFHLSSKLLFKRM 209 Query: 714 VIPPACWRLMYRYGFGPEKKMAVARRIIDRFAA-----DTIVKRRYSGHKLRGEGITESS 878 + P +++ + + R + ++ ++++++R GE + Sbjct: 210 INPLLSSDWIFQ-------RTQLWRDLDEQLQVIHSQMESVIEKRAKELLDMGEPAGRAH 262 Query: 879 DIL-SFFICNDDASEHSDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDE 1055 ++L + + + S +RD +FAG DTT A +S+ Y L + P + + E Sbjct: 263 NLLDTLLLAKFEGQSLSRREIRDEINTFVFAGVDTTTAAMSFVLYALAKFPETQTRLRKE 322 Query: 1056 LAPIAARKKVDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEI 1235 L +A +D+ LDA L+ + YL A + E LRLY VP T + T + + G Sbjct: 323 LQDVA----LDETTDLDA--LNGLPYLEALIKEVLRLYTIVPTTGRQTTQSTEI-GGRTY 375 Query: 1236 KAGDKILVYSYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGK 1415 AG + + Y + + + D F PERW+ +DG + P + +I F+ GP C+G+ Sbjct: 376 CAGVTLWINMYGLAHDKEYY-PDPYAFKPERWLPEDGAVA-PPAFSYIPFSGGPHVCIGR 433 Query: 1416 EVAFTQMKTVAATVLWNFTLETVPGHT-VKPKLSIVLHMKNGLAVT 1550 + MK + A ++ F +E P ++ + +VL + G+ V+ Sbjct: 434 RYSLLLMKLLTARLVREFQMELSPEQAPLRLEAQMVLKAQQGINVS 479
>Q8K4D6:CP4X1_RAT Cytochrome P450 4X1 - Rattus norvegicus (Rat)| Length = 507 Score = 95.9 bits (237), Expect = 5e-19 Identities = 63/216 (29%), Positives = 98/216 (45%), Gaps = 8/216 (3%) Frame = +3 Query: 909 DASEHSDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVD 1088 D SD LR ++AG D + A +SW Y L NP + E+ I + Sbjct: 295 DEKAFSDADLRSEVNTFMWAGHDASAASISWLLYCLALNPEHQDRCRTEIRSI-----LG 349 Query: 1089 DMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSY 1268 D + +L + Y + E LRL P +P + + LP GH + AG +++ + Sbjct: 350 DGSSITWEQLDEIPYTTMCIKETLRLIPPIPSISRELSKPLTLPDGHSLPAGMTVVLSIW 409 Query: 1269 SMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVA 1448 + VW KD F P R+ ++ + RH P F+ F++GPR C+G++ A ++K Sbjct: 410 GLHHNPAVW-KDPKVFDPLRFTKENSEQRH--PCAFLPFSSGPRNCIGQQFAMLELKVAI 466 Query: 1449 ATVLWNFTL-------ETVPGHTV-KPKLSIVLHMK 1532 A L F + HTV +PK I LH+K Sbjct: 467 ALTLLRFRVAADLTRPPAFSSHTVLRPKHGIYLHLK 502
>Q9V559:CP4P3_DROME Probable cytochrome P450 4p3 - Drosophila melanogaster (Fruit fly)| Length = 515 Score = 95.9 bits (237), Expect = 5e-19 Identities = 103/424 (24%), Positives = 177/424 (41%), Gaps = 15/424 (3%) Frame = +3 Query: 336 NSINYPRGEEYADIFDVLGDGIFNADGESWRRQRAKSQLIMASPRFRSFSARCTRDKVER 515 N IN +G Y + L G+ + G+ W +R M SP F ++ Sbjct: 110 NLIN--KGTIYDFLHPFLRTGLLTSTGKKWHARRK-----MLSPTFHFNILNQFQEIFIT 162 Query: 516 SLLPFLAH-AADVGARCDLHDVLLRLMFDMTCNLVFGVDPGCLQIGLPSLPLARAMDDVL 692 L FL + A L++V+ R + C GV L R + Sbjct: 163 ESLKFLEQFKGNDEAIISLNEVIPRFTLNSICETAMGVK---LDEMAEKGDRYRENFRQI 219 Query: 693 ETLFLRHVIPPACWRLMYRYGFGPEKKMAVARRIIDRFAADTIVKRRYS-GHKLRGEGIT 869 E F+R + P W F EK A A ++ F+++ I KRR ++ G T Sbjct: 220 EECFIRRMSNPLLWSDTLFKMFA-EKDYASALDVVHGFSSEIIAKRRDQLNDEIDSRGNT 278 Query: 870 ESSD-----------ILSFFICNDDASEHSDEFLRDTAVNLLFAGRDTTGAVLSWFFYLL 1016 ++++ +L I + + + L+F G DTT L + + Sbjct: 279 QTAEDELFTSKKRFAMLDTLILAEKDGLIDHIGICEEVDTLMFEGYDTTSIGLMFGLMNM 338 Query: 1017 CENPRVEQMILDELAPIAARKKVDDMV-VLDASELSSMVYLHAALCECLRLYPSVPITHK 1193 P ++ E+ + +DD + +L+ +L+ + L + E +RL+PSVP + Sbjct: 339 SLYPEEQEKCYQEI-----QANIDDELNILNIGQLNKLKNLEYFIKETMRLFPSVPAMGR 393 Query: 1194 AATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYK 1373 T L +G + G +I V+ + + R W EF PER++ ++ + RH Y Sbjct: 394 ETTRETELSNGLILPKGSQIFVHVFDIHRNPEYWDSP-EEFRPERFLPENSQNRH--TYA 450 Query: 1374 FIAFNAGPRTCLGKEVAFTQMKTVAATVLWNF-TLETVPGHTVKPKLSIVLHMKNGLAVT 1550 +I F+AG R C+G++ A +MKT+ +L F L + T+ + + L KN + V Sbjct: 451 YIPFSAGQRNCIGQKFAMQEMKTLMVALLKQFQILPEIDPKTIVFQTGLTLRTKNQIHVK 510 Query: 1551 VKRR 1562 + RR Sbjct: 511 LVRR 514
>P14579:CP4A5_RABIT Cytochrome P450 4A5 precursor - Oryctolagus cuniculus (Rabbit)| Length = 511 Score = 95.9 bits (237), Expect = 5e-19 Identities = 70/277 (25%), Positives = 119/277 (42%), Gaps = 7/277 (2%) Frame = +3 Query: 750 YGFGPEKKMAVARRIIDRFAADTIVKRRYSG-------HKLRGEGITESSDILSFFICND 908 Y PE +++ + D ++++R + K+R + + D+L F + Sbjct: 244 YRLSPEGRLSHRACQLAHEHTDRVIQQRKAQLQQEGELEKVRRKRRLDFLDVL-LFAKME 302 Query: 909 DASEHSDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVD 1088 + S SD+ LR +F G DTT + +SW FY L +P + +E+ + + Sbjct: 303 NGSSLSDQDLRAEVDTFMFEGHDTTASGVSWIFYALATHPEHQHRCREEIQGL-----LG 357 Query: 1089 DMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSY 1268 D + L M Y + E +RLYP VP + + P G + G + + Y Sbjct: 358 DGASITWEHLDQMPYTTMCIKEAMRLYPPVPAISRDLSSPVTFPDGRSLPKGFTVTLSIY 417 Query: 1269 SMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVA 1448 + VW + F P R+ G RH + F+ F+ G R C+GK+ A ++K Sbjct: 418 GLHHNPNVWPNPEV-FDPGRFTP--GSARHS--HAFLPFSGGARNCIGKQFAMNELKVAV 472 Query: 1449 ATVLWNFTLETVPGHTVKPKLSIVLHMKNGLAVTVKR 1559 A L F L P KP +VL NG+ + +++ Sbjct: 473 ALTLVRFELLPDPTRIPKPTARLVLKSNNGIHLRLRK 509
>Q07973:CP24A_HUMAN Cytochrome P450 24A1, mitochondrial precursor - Homo sapiens (Human)| Length = 514 Score = 95.9 bits (237), Expect = 5e-19 Identities = 115/469 (24%), Positives = 194/469 (41%), Gaps = 19/469 (4%) Frame = +3 Query: 153 PTEWPLLGHLLSTL--ANVSNLHDWATGVLATTRYNFAAHMGLTGVRFFLTCDPSNVRHI 326 PT WPLLG LL L + HD T V +Y M L P + + Sbjct: 61 PTSWPLLGSLLQILWKGGLKKQHD--TLVEYHKKYGKIFRMKLGSFESVHLGSPCLLEAL 118 Query: 327 FISNSINYPRGEE------YADIFDVLGDGIFNADGESWRRQRAKSQLIMASPRFRSFSA 488 + + S YP+ E Y D + G G+ +GE W+R R+ Q + P Sbjct: 119 YRTESA-YPQRLEIKPWKAYRD-YRKEGYGLLILEGEDWQRVRSAFQKKLMKPG----EV 172 Query: 489 RCTRDKVERSLLPFLAHAADV----GARCDLHDVLLRLMFDMTCNLVFGVDPGCLQ--IG 650 +K+ L F+ ++ G DL+ L + F+ C +++ G LQ G Sbjct: 173 MKLDNKINEVLADFMGRIDELCDERGHVEDLYSELNKWSFESICLVLYEKRFGLLQKNAG 232 Query: 651 LPSLPLARAMDDVLETLFLRHVIPPACWRLMYRYGFGPEKKMAVARRIID--RFAADTIV 824 ++ A+ ++ T F R ++ P E ++ ++ A DTI Sbjct: 233 DEAVNFIMAIKTMMST-FGRMMVTPV------------ELHKSLNTKVWQDHTLAWDTIF 279 Query: 825 K--RRYSGHKLRGEGITESSDILSFFICND-DASEHSDEFLRDTAVNLLFAGRDTTGAVL 995 K + ++L S+D F+C+ + S + L L A +TT L Sbjct: 280 KSVKACIDNRLEKYSQQPSAD----FLCDIYHQNRLSKKELYAAVTELQLAAVETTANSL 335 Query: 996 SWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAALCECLRLYPS 1175 W Y L NP+V+Q +L E+ + +V A +L +M YL A L E +RL PS Sbjct: 336 MWILYNLSRNPQVQQKLLKEIQSVLPENQVP-----RAEDLRNMPYLKACLKESMRLTPS 390 Query: 1176 VPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWITDDGKLR 1355 VP T + VL + + G +++ + +G E + +D +F PERW+ + K+ Sbjct: 391 VPFTTRTLDKATVL-GEYALPKGTVLMLNTQVLGSSEDNF-EDSSQFRPERWLQEKEKIN 448 Query: 1356 HQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLETVPGHTVK 1502 P+ + F G R C+G+ +A Q+ ++ + ++ V+ Sbjct: 449 ---PFAHLPFGVGKRMCIGRRLAELQLHLALCWIVRKYDIQATDNEPVE 494
>Q92045:CP11A_DASAM Cytochrome P450 11A1, mitochondrial precursor - Dasyatis americana| (Southern stingray) Length = 514 Score = 95.9 bits (237), Expect = 5e-19 Identities = 97/388 (25%), Positives = 178/388 (45%), Gaps = 12/388 (3%) Frame = +3 Query: 396 GIFNADGESWRRQRAKSQLIMASPRFRSFSARCTRDKVERSLLPFLA--HAADVGARCD- 566 G+ +GE+W+R R LI+ + F S + +L F++ H +R D Sbjct: 139 GVQLLNGENWKRTR----LILNNSIFAQSSIQRLVPLFNEVVLDFVSMVHKEVEKSRSDY 194 Query: 567 ----LHDVLLRLMFDMTCNLVFGVDPGCLQIGLPSLPLARAMDDVLETLF----LRHVIP 722 L + L +L ++ C +++G LQ P + D + T+F + +P Sbjct: 195 WKTDLTNDLFKLALEVICYILYGERLDLLQRKYNKAP--QKFIDSIATMFHSTPIMLYVP 252 Query: 723 PACWRLMYRYGFGPEKKMAVARRIIDRFAADTIVKRRYSGHKLRGEGITESSDILSFFIC 902 P+ + + + ++ + I + ADT +K+ Y + + +L+ + Sbjct: 253 PSLLKSINSKIW--QQHVGSWDNIFEH--ADTYLKKAYRQFQQGSKNEHAFPGVLTELLL 308 Query: 903 NDDASEHSDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKK 1082 E +R + ++++ DTT + W Y L ++P +++ + E+ A +K Sbjct: 309 QGALPF---EDIRASIIDVMSGAIDTTSTTVHWMMYELAKHPHIQKNVRSEIME-AHQKT 364 Query: 1083 VDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVY 1262 D V + L S+ L + E LRLYP V I+ + + D + + I AG + + Sbjct: 365 EGDPVKM----LKSVPLLKCVVKETLRLYP-VAISIQRYLNEDTVLQNYHIPAGTLVQLG 419 Query: 1263 SYSMGRMEGVWGKDCMEFSPERWIT-DDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMK 1439 Y+MGR ++ K+ +++PERW+ +D RH + F GPR C+G+ +A TQM Sbjct: 420 LYAMGRNPKIF-KNPEQYNPERWLKGEDTHFRH------LGFGFGPRQCIGRRIAETQMV 472 Query: 1440 TVAATVLWNFTLETVPGHTVKPKLSIVL 1523 + +L NF +ET P VK K S++L Sbjct: 473 LLMIHMLQNFKIETDPMTEVKSKFSLIL 500
>Q99N16:CP4F3_MOUSE Cytochrome P450 4F3 - Mus musculus (Mouse)| Length = 524 Score = 95.5 bits (236), Expect = 6e-19 Identities = 98/405 (24%), Positives = 168/405 (41%), Gaps = 15/405 (3%) Frame = +3 Query: 387 LGDGIFNADGESWRRQRAKSQLIMASPRFRSFS-----ARCTRDKVERSLLPFLAHAADV 551 LGDG+ + G+ W R R M +P F F+ + D + A+ Sbjct: 132 LGDGLLMSTGDKWSRHRR-----MLTPAFH-FNILKPYVKVFNDSTNIMHAKWQRLASKG 185 Query: 552 GARCDLHDVLLRLMFDMTCNLVFGVDPGCLQIGLPSLPLARAMDDVLETLFLRHVIPPAC 731 A ++ + + + D VF D C + PS + ++ L L R Sbjct: 186 SAYLNMFEHISLMTLDSLQKCVFSFDSNCQE--KPSEYITAILE--LSALVARRHQRLLL 241 Query: 732 WRLMYRYGFGPEKKMAVARRIIDRFAADTIVKRRYS------GHKLRGEGITESSDILSF 893 ++ Y + A R++ F I +RR + L+ + ++ D + Sbjct: 242 HVDLFYYLTHDGMRFRKACRLVHDFTDAVIRERRRTLLDQGGDDVLKAKAKAKTLDFIDV 301 Query: 894 FICNDDASEH----SDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELA 1061 + + D EH SDE +R A +F G DTT + LSW Y L +P ++ E+ Sbjct: 302 LLLSKD--EHGKALSDEDIRAEADTFMFGGHDTTASGLSWILYNLARHPEYQERCRQEVR 359 Query: 1062 PIAARKKVDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKA 1241 + ++ ++ ++ +L+ + +L + E LRL+P V + T + VLP G I Sbjct: 360 ELLRDREPEE---IEWDDLAQLPFLTMCIKESLRLHPPVTAISRCCTQDIVLPDGRVIPK 416 Query: 1242 GDKILVYSYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEV 1421 G + + VW D + P R+ D+ K R P FI F+AGPR C+G+ Sbjct: 417 GVISRISIFGTHHNPAVW-PDPEVYDPFRFDADNVKGR--SPLAFIPFSAGPRNCIGQTF 473 Query: 1422 AFTQMKTVAATVLWNFTLETVPGHTVKPKLSIVLHMKNGLAVTVK 1556 A ++MK A L F + + K ++L + GL + V+ Sbjct: 474 AMSEMKVALALTLLRFRV-LPDDKEPRRKPELILRAEGGLWLKVE 517
>P08516:CP4AA_RAT Cytochrome P450 4A10 - Rattus norvegicus (Rat)| Length = 509 Score = 95.5 bits (236), Expect = 6e-19 Identities = 61/212 (28%), Positives = 97/212 (45%) Frame = +3 Query: 924 SDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVL 1103 SD+ LR +F G DTT + +SW FY L +P +Q +E+ + + D + Sbjct: 306 SDKDLRAEVDTFMFEGHDTTASGVSWIFYALATHPEHQQRCREEVQSV-----LGDGSSI 360 Query: 1104 DASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRM 1283 L + Y + E LRLYP VP + + + P G + G ++ + Y + Sbjct: 361 TWDHLDQIPYTTMCIKEALRLYPPVPGIVRELSTSVTFPDGRSLPKGIQVTLSIYGLHHN 420 Query: 1284 EGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLW 1463 VW + F P R+ D + H F+ F+ G R C+GK+ A ++MK + A L Sbjct: 421 PKVWPNPEV-FDPSRFAPDSPRHSHS----FLPFSGGARNCIGKQFAMSEMKVIVALTLL 475 Query: 1464 NFTLETVPGHTVKPKLSIVLHMKNGLAVTVKR 1559 F L P P +VL KNG+ + +K+ Sbjct: 476 RFELLPDPTKVPIPLPRLVLKSKNGIYLYLKK 507
>Q9Y6A2:CP46A_HUMAN Cytochrome P450 46A1 - Homo sapiens (Human)| Length = 500 Score = 95.5 bits (236), Expect = 6e-19 Identities = 105/439 (23%), Positives = 187/439 (42%), Gaps = 9/439 (2%) Frame = +3 Query: 294 LTCDPSNVRHIFISNSINYPRGEEYADIFDVLGDGIFN------ADGESWRRQRAKSQLI 455 + P +V+ +S N + Y + V G+ +F + E W +QR L Sbjct: 86 IVTSPESVKKFLMSTKYNKD-SKMYRALQTVFGERLFGQGLVSECNYERWHKQRRVIDL- 143 Query: 456 MASPRFRSFSARCTRDKVERSLLPFLAHAADVGARCDLHDVLLRLMFDMTCNLVFGVDPG 635 A R S T ++ L+ L AD + D+L D+ FG++ Sbjct: 144 -AFSRSSLVSLMETFNEKAEQLVEILEAKADGQTPVSMQDMLTYTAMDILAKAAFGMETS 202 Query: 636 CLQIGLPSLPLARAMDDVLETLFLRHVIPPACWRLMYRYGFGPEKKMAVAR---RIIDRF 806 L +G PL++A+ +LE + A + ++ G K++ R R + + Sbjct: 203 ML-LGAQK-PLSQAVKLMLEGI-------TASRNTLAKFLPGKRKQLREVRESIRFLRQV 253 Query: 807 AADTIVKRRYSGHKLRGEGITESSDILSFFICNDDASEHSDEFLRDTAVNLLFAGRDTTG 986 D + +RR + RGE + +DIL+ + ++ ++ DE L D V AG +T+ Sbjct: 254 GRDWVQRRREA--LKRGEEVP--ADILTQILKAEEGAQ-DDEGLLDNFVTFFIAGHETSA 308 Query: 987 AVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAALCECLRL 1166 L++ L P + + E+ + K+ LD +L + YL L E LRL Sbjct: 309 NHLAFTVMELSRQPEIVARLQAEVDEVIGSKRY-----LDFEDLGRLQYLSQVLKESLRL 363 Query: 1167 YPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWITDDG 1346 YP T + + L G + +L +Y MGRM+ + +D + F+P+R+ G Sbjct: 364 YPPAWGTFRLL-EEETLIDGVRVPGNTPLLFSTYVMGRMD-TYFEDPLTFNPDRF----G 417 Query: 1347 KLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLETVPGHTVKPKLSIVLH 1526 +P + + F+ G R+C+G++ A ++K V A +L VPG + L Sbjct: 418 PGAPKPRFTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQRLEFRLVPGQRFGLQEQATLK 477 Query: 1527 MKNGLAVTVKRRNFFTAKP 1583 + + T++ R + A P Sbjct: 478 PLDPVLCTLRPRGWQPAPP 496
>O65438:C71AR_ARATH Cytochrome P450 71A27 - Arabidopsis thaliana (Mouse-ear cress)| Length = 499 Score = 95.5 bits (236), Expect = 6e-19 Identities = 89/381 (23%), Positives = 158/381 (41%), Gaps = 7/381 (1%) Frame = +3 Query: 393 DGIFNADGESWRRQRAKSQL-IMASPRFRSFSARCTRDKVERSLLPFLAHAADVGARCDL 569 D IF GE W+ ++ + ++ + RSF R++ + + L A+ + +L Sbjct: 115 DIIFGPYGEDWKSMKSLGVVHLLNNKMVRSFEN--LREEEIKVMTEKLEEASSSSSSVNL 172 Query: 570 HDVLLRLMFDMTCNLVFGVDPGCLQIGLPSLPLARAMDDVLETLFLRHVIPPACWRLMYR 749 +L+ L D+ C + G + G+ L + F IP W Sbjct: 173 SKLLMTLTNDIICRITLGRKYNEEEGGIDIKNLVMTSSEFFGKFFFGDFIPSLAW---ID 229 Query: 750 YGFGPEKKMAVARRIIDRFAADTIVKRRYSGHKLRGEGITESSDILSFFICNDDASEHSD 929 + G + KM +D F + + + HK E SD + + Sbjct: 230 WISGIDDKMKDINNKLDCFLDSMVQEHVDADHK-------EPSDFIDMLLLIQKDKTKRF 282 Query: 930 EFLRDTAVNLL----FAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMV 1097 +F R + +L F+G TT + L W L +P + + DE+ + + Sbjct: 283 KFDRSDLILILKDMFFSGTATTASQLEWTMTELMRHPECMKKLQDEINSFSTHN-----L 337 Query: 1098 VLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMG 1277 + E+ M YLH + E LRL+PS P+ + + DV G++I AG +++ ++++ Sbjct: 338 NVTEKEVEKMNYLHCVIKEGLRLHPSGPLLFRLPSE-DVQLKGYDISAGTHVIINAWALQ 396 Query: 1278 RMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATV 1457 R +WG D E+ PER + + + KF+ F AG R C G + K A + Sbjct: 397 RNPAIWGLDANEYRPERHFWYEFGFQ-RTDSKFVPFGAGRRLCPGIGFSLVLSKLALANL 455 Query: 1458 L--WNFTLETVPGHTVKPKLS 1514 + +N+ L+ P KP L+ Sbjct: 456 VKRFNWRLKVGPVGDDKPDLA 476
>P30609:CP52G_CANTR Cytochrome P450 52A7 - Candida tropicalis (Yeast)| Length = 507 Score = 95.1 bits (235), Expect = 8e-19 Identities = 107/442 (24%), Positives = 164/442 (37%), Gaps = 30/442 (6%) Frame = +3 Query: 279 GVRFFLTCDPSNVRHIFISNSINYPRGEEYADIFDVLGDGIFNADGESWRRQRAKSQLIM 458 G T DP N++ + + ++ G +LG GIF DGE W+ RA M Sbjct: 87 GNHVIFTRDPENIKALLATQFNDFSLGGRIKFFKPLLGYGIFTLDGEGWKHSRA-----M 141 Query: 459 ASPRFRSFSARCTRDKVERSLLPFL---AHAADVGARCDLHDVLLRLMFDMTCNLVFGVD 629 P+F + SL P A+ + D+ ++ R D +FG Sbjct: 142 LRPQFAREQL-----PMSPSLEPHFNVKAYPQEQRWVFDIQELFFRFTVDSATEFLFGES 196 Query: 630 PGCLQ---IGLPS-------LPLARAMDDVLETLFLRHVIPPACWRLMYRYGFGPEKKMA 779 L+ IG A A + E + R + W F + Sbjct: 197 VNSLKSASIGCDEETELEERKKFAEAFNKAQEYISTRVALQQLYW-------FVNNSEFK 249 Query: 780 VARRIIDRFAADTIVK---------RRYSGHKLRGEGITESSDILSFFICNDDASEHSDE 932 I+ +F + K + SG+ E + ++ D Sbjct: 250 ECNEIVHKFTNYYVQKALDATPEELEKQSGYVFLYELVKQTRD---------------PN 294 Query: 933 FLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDAS 1112 LRD L AGRDTT +LS+ + L NP + + +++ + + + Sbjct: 295 VLRDHHSISLLAGRDTTAGLLSFAVFELARNPHIWAKLREDVESQFGLGEESRIEEITFE 354 Query: 1113 ELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMG-RMEG 1289 L YL A + E LRL+PSVP + A + LP G D ILV S + G Sbjct: 355 SLKRCEYLKAVMNETLRLHPSVPRNARFALKDTTLPRGGGPDGKDPILVRKMSCSIFISG 414 Query: 1290 V------WGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAA 1451 +GKD F PERW + + ++ FN GPR CLG++ A T+ + Sbjct: 415 TQIDPKHYGKDAKLFRPERWFESSTR---NLGWAYLPFNGGPRICLGQQFALTEAGYILV 471 Query: 1452 TVLWNF-TLETVPGHTVKPKLS 1514 + +F TLE P K+S Sbjct: 472 RLAQSFDTLELKPDTEYLTKIS 493
>P29981:CP4C1_BLADI Cytochrome P450 4C1 - Blaberus discoidalis (Tropical cockroach)| Length = 511 Score = 95.1 bits (235), Expect = 8e-19 Identities = 94/388 (24%), Positives = 170/388 (43%), Gaps = 15/388 (3%) Frame = +3 Query: 366 YADIFDVLGDGIFNADGESWRRQRAKSQLIMASPRFRSFSARCTRDK-VERSLLPFLAHA 542 Y+ I LG+G+ G W R M +P F D VE+S + Sbjct: 108 YSFIRPWLGEGLLTGTGAKWHSHRK-----MITPTFHFKILDIFVDVFVEKSEILVKKLQ 162 Query: 543 ADVGAR-CDLHDVLLRLMFDMTCNLVFGVDPGCLQIGLPSLPLARAMDDVLETLFLRHVI 719 + VG + D++ + D+ C G+ + +A+ ++ E R V Sbjct: 163 SKVGGKDFDIYPFITHCALDIICETAMGIQMNAQEES--ESEYVKAVYEISELTMQRSVR 220 Query: 720 PPACWRLMYRYGFGPEKKMAVARRIIDRFAADTIVKRRYSGHKLRGEGITESSDI----- 884 P ++++ K+ A RI+ F + +++ R S ++ G T S++ Sbjct: 221 PWLHPKVIFDLTT-MGKRYAECLRILHGFT-NKVIQERKSLRQMTGMKPTISNEEDELLG 278 Query: 885 ----LSFFICNDDASEH----SDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQ 1040 L+F +ASE+ SD +R+ +F G DTT A + W +LL +P ++ Sbjct: 279 KKKRLAFLDLLLEASENGTKMSDTDIREEVDTFMFEGHDTTSAGICWALFLLGSHPEIQD 338 Query: 1041 MILDELAPIAARKKVDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLP 1220 + +EL I + +L+ M YL + E LRL+PSVP + D Sbjct: 339 KVYEELDHIFQGSDRSTTM----RDLADMKYLERVIKESLRLFPSVPFIGRVLKE-DTKI 393 Query: 1221 SGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPR 1400 + + AG + + Y + R + + F+P+ ++ + RH PY ++ F+AGPR Sbjct: 394 GDYLVPAGCMMNLQIYHVHRNQDQYPNP-EAFNPDNFLPERVAKRH--PYAYVPFSAGPR 450 Query: 1401 TCLGKEVAFTQMKTVAATVLWNFTLETV 1484 C+G++ A + KTV +++L NF + ++ Sbjct: 451 NCIGQKFATLEEKTVLSSILRNFKVRSI 478
>Q8SPK1:CP4AO_PIG Cytochrome P450 4A24 - Sus scrofa (Pig)| Length = 504 Score = 95.1 bits (235), Expect = 8e-19 Identities = 62/212 (29%), Positives = 93/212 (43%) Frame = +3 Query: 924 SDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVL 1103 SD LR +F G DTT + +SW Y L +P +Q +E+ + + D + Sbjct: 301 SDTDLRAEVDTFMFEGHDTTASGISWILYALASHPEHQQRCREEIQGL-----LGDGTSI 355 Query: 1104 DASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRM 1283 L M Y + E LRLYP VP + + P G + AG + + Y + Sbjct: 356 TWDHLDQMPYTTMCIKEALRLYPPVPGVSRELSKPITFPDGRSLPAGITLSLSIYGLHHN 415 Query: 1284 EGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLW 1463 VW EF P R+ G RH + F+ F+ G R C+GK+ A +MK A L Sbjct: 416 PQVWPNP-EEFDPSRFAP--GSARHS--HAFMPFSGGSRNCIGKQFAMNEMKVAVALTLL 470 Query: 1464 NFTLETVPGHTVKPKLSIVLHMKNGLAVTVKR 1559 F L P +VL+ KNG+ + +++ Sbjct: 471 RFELAPDPSRKPIATPEVVLNSKNGIHLKLRK 502
>P10611:CP4A4_RABIT Cytochrome P450 4A4 precursor - Oryctolagus cuniculus (Rabbit)| Length = 510 Score = 95.1 bits (235), Expect = 8e-19 Identities = 104/440 (23%), Positives = 174/440 (39%), Gaps = 18/440 (4%) Frame = +3 Query: 294 LTCDPSNVRHIFISNSINYPRGEEYADIFDVLGDGIFNADGESWRRQRAKSQLIMASPRF 473 L DP ++ I + PR Y + +G G+ DG++W + R M +P F Sbjct: 98 LVYDPDYLKVILGRSDPKAPRN--YKLMTPWIGYGLLLLDGQTWFQHRR-----MLTPAF 150 Query: 474 RSF-----------SARCTRDKVERSLLPFLAHAADVGARCDLHDVLLRLMFDMTCNLVF 620 S + D+ E+ + + D H L+ L M C + Sbjct: 151 HYDILKPYVGLMVDSVQIMLDRWEQLI------SQDSSLEIFQHVSLMTLDTIMKCAFSY 204 Query: 621 GVDPGCLQIGLPSLPLARAMDDVLETLFLRHVIPPACWRLMYRYGFGPEKKM-----AVA 785 G +Q+ S +A++D+ +F R + + Y PE ++ +A Sbjct: 205 ---QGSVQLDRNSHSYIQAINDLNNLVFYR--ARNVFHQSDFLYRLSPEGRLFHRACQLA 259 Query: 786 RRIIDRFAADTIVKRRYSGH--KLRGEGITESSDILSFFICNDDASEHSDEFLRDTAVNL 959 DR + + G K+R + + D+L F ++ S SD+ LR Sbjct: 260 HEHTDRVIQQRKAQLQQEGELEKVRRKRRLDFLDVL-LFAKMENGSSLSDQDLRAEVDTF 318 Query: 960 LFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLH 1139 +F G DTT + +SW FY L +P + +E+ + + D + L M Y Sbjct: 319 MFEGHDTTASGVSWIFYALATHPEHQHRCREEIQGL-----LGDGASITWEHLDQMPYTT 373 Query: 1140 AALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFS 1319 + E LRLYP VP + + P G + G + + Y + VW ++ F Sbjct: 374 MCIKEALRLYPPVPSVTRQLSKPVTFPDGRSLPKGVILFLSIYGLHYNPKVW-QNPEVFD 432 Query: 1320 PERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLETVPGHTV 1499 P R+ D H F+ F+ G R C+GK+ A ++K A L F L P Sbjct: 433 PFRFAPDSAYHSHA----FLPFSGGARNCIGKQFAMRELKVAVALTLVRFELLPDPTRIP 488 Query: 1500 KPKLSIVLHMKNGLAVTVKR 1559 P +VL KNG+ + +++ Sbjct: 489 IPIARVVLKSKNGIHLRLRK 508
>Q9WVK8:CP46A_MOUSE Cytochrome P450 46A1 - Mus musculus (Mouse)| Length = 500 Score = 95.1 bits (235), Expect = 8e-19 Identities = 105/439 (23%), Positives = 187/439 (42%), Gaps = 9/439 (2%) Frame = +3 Query: 294 LTCDPSNVRHIFISNSINYPRGEEYADIFDVLGDGIFN------ADGESWRRQRAKSQLI 455 + P +V+ +S N + Y + V G+ +F D W +QR L Sbjct: 86 IVTSPESVKKFLMSTKYNKD-SKMYRALQTVFGERLFGQGLVSECDYGRWYKQRKVMDL- 143 Query: 456 MASPRFRSFSARCTRDKVERSLLPFLAHAADVGARCDLHDVLLRLMFDMTCNLVFGVDPG 635 A R S T ++ L+ L AD + D+L D+ FG++ Sbjct: 144 -AFSRSSLVSLMETFNEKAEQLVEILEAKADGQTPVSMQDMLTCATIDILAKAAFGMETS 202 Query: 636 CLQIGLPSLPLARAMDDVLETLFLRHVIPPACWRLMYRYGFGPEKKMAVAR---RIIDRF 806 L +G PL++A+ +LE + A + ++ G K++ R R++ + Sbjct: 203 ML-LGAQK-PLSQAVKVMLEGI-------SASRNTLAKFMPGKRKQLREIRESIRLLRQV 253 Query: 807 AADTIVKRRYSGHKLRGEGITESSDILSFFICNDDASEHSDEFLRDTAVNLLFAGRDTTG 986 D + +RR + RGE + +DIL+ + ++ ++ DE L D V AG +T+ Sbjct: 254 GKDWVQRRREA--LKRGEDMP--ADILTQILKAEEGAQ-DDEVLLDNFVTFFIAGHETSA 308 Query: 987 AVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAALCECLRL 1166 L++ L P + + E+ + K+ LD +L + YL L E LRL Sbjct: 309 NHLAFTVMELSRQPEIVARLQAEVDEVVGSKRH-----LDYEDLGRLQYLSQVLKESLRL 363 Query: 1167 YPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWITDDG 1346 YP T + + L G + +L +Y MGRM+ + +D + F+P+R+ G Sbjct: 364 YPPAWGTFRLL-EEETLIDGVRVPGNTPLLFSTYVMGRMD-TYFEDPLTFNPDRF----G 417 Query: 1347 KLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLETVPGHTVKPKLSIVLH 1526 +P + + F+ G R+C+G++ A ++K V A +L VPG + L Sbjct: 418 PGAPKPRFTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQRIEFRLVPGQRFGLQEQATLK 477 Query: 1527 MKNGLAVTVKRRNFFTAKP 1583 + + T++ R + A P Sbjct: 478 PLDPVLCTLRPRGWQPAPP 496
>Q9W011:C4D20_DROME Probable cytochrome P450 4d20 - Drosophila melanogaster (Fruit fly)| Length = 510 Score = 95.1 bits (235), Expect = 8e-19 Identities = 110/511 (21%), Positives = 204/511 (39%), Gaps = 29/511 (5%) Frame = +3 Query: 117 RRLQSKKTTKEEPTEWPLLGHLLSTL-ANVSNLHDWATGVLATTRYNFAAHMGLTGVRFF 293 R L +K+ P P+LG L L N+ W +Y + G Sbjct: 24 RVLAFEKSAIPGPISIPILGCGLQALHLGAENIIGWVGEKF--DKYGKTFRFWILGESLI 81 Query: 294 LTCDPSNVRHIFISNSINYPRGEEYADIFDVLGDGIFNADGESWRRQRAKSQLIMASPRF 473 T D I S ++ +G+ Y + L DG+ + G W +R ++ + F Sbjct: 82 YTKDLQYFETILSSTTL-LEKGQLYEYLRPFLNDGLLVSTGRKWHARR---KIFTHAFHF 137 Query: 474 RSFSARCT-RDKVERSLLPFLAHAADVGARCDLHDVLLRLMFDMTCNLVFGVDPGCLQIG 650 + D+ ++ L AD D+ + D+ GV Sbjct: 138 KVLEHYVEIMDRHSSVMVDNLRKVADGKTAVDMLKYVSLAALDVITEAAMGVQVNAQND- 196 Query: 651 LPSLPLARAMDDVLETLFLRHVIPPACWRLMYRYGF-----GP--EKKMAVARRIIDRFA 809 P P +A+ V+ ++ P +R RY + P +++ R++ F Sbjct: 197 -PDFPYIKALKSVV------YIQPDRMFRFSRRYNWLFPLAAPLLHRQLLSDIRVMHDFT 249 Query: 810 ADTIVKRRYSGHKLRGEGI------------TESSDILSFFICNDDASEH--SDEFLRDT 947 I +RR + + + +G ++S L + + SD +R+ Sbjct: 250 DKVISERRETVRRAKADGTYRPLSLGDAEIGSKSQMALLDILLQSSINNQPLSDADIREE 309 Query: 948 AVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSM 1127 +F G DTT + +S Y + +P V+Q I +EL + D + ++L + Sbjct: 310 VDTFMFEGDDTTSSGVSHALYAIARHPEVQQRIFEELQRVLGP---DASAPVTQAQLQDL 366 Query: 1128 VYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSM------GRMEG 1289 YL + E +RLYP VP + A E++ GDK + + S+ + Sbjct: 367 KYLDCVIKETMRLYPPVPAIGRHAQK--------ELEIGDKTIPANTSIYLVLYYAHRDA 418 Query: 1290 VWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNF 1469 + D + F PER++ D + + + ++ F+AGP+ C+G++ A +MK + + VL + Sbjct: 419 NYFPDPLSFRPERFLEDQEQGHNT--FAYVPFSAGPKNCIGQKFAVLEMKVLISKVLRFY 476 Query: 1470 TLETVPGHTVKPKLSIVLHMKNGLAVTVKRR 1562 L + G +KP L+ +L +G+ V ++ R Sbjct: 477 ELLPL-GEELKPMLNFILRSASGINVGLRPR 506
>P14779:CPXB_BACME Bifunctional P-450:NADPH-P450 reductase - Bacillus megaterium| Length = 1049 Score = 94.7 bits (234), Expect = 1e-18 Identities = 80/302 (26%), Positives = 134/302 (44%), Gaps = 3/302 (0%) Frame = +3 Query: 666 LARAMDDVLETLFLRHVIPPACWRLMYRYGFGPEKKMAVARRIIDRFAADTIVKRRYSGH 845 + RA+D+ + L + PA ++ ++ + V ++D+ AD R+ SG Sbjct: 178 MVRALDEAMNKLQRANPDDPAYDENKRQF----QEDIKVMNDLVDKIIAD----RKASGE 229 Query: 846 KLRGEGITESSDILSFFICNDDASEHS---DEFLRDTAVNLLFAGRDTTGAVLSWFFYLL 1016 +S D+L+ + D DE +R + L AG +TT +LS+ Y L Sbjct: 230 --------QSDDLLTHMLNGKDPETGEPLDDENIRYQIITFLIAGHETTSGLLSFALYFL 281 Query: 1017 CENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKA 1196 +NP V Q +E AAR VD V ++ + Y+ L E LRL+P+ P Sbjct: 282 VKNPHVLQKAAEE----AARVLVDP--VPSYKQVKQLKYVGMVLNEALRLWPTAPAFSLY 335 Query: 1197 ATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKF 1376 A + VL + ++ GD+++V + R + +WG D EF PER+ P + F Sbjct: 336 AKEDTVLGGEYPLEKGDELMVLIPQLHRDKTIWGDDVEEFRPERFENPSA----IPQHAF 391 Query: 1377 IAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLETVPGHTVKPKLSIVLHMKNGLAVTVK 1556 F G R C+G++ A + V +L +F E + + K ++ L G V K Sbjct: 392 KPFGNGQRACIGQQFALHEATLVLGMMLKHFDFEDHTNYELDIKETLTL-KPEGFVVKAK 450 Query: 1557 RR 1562 + Sbjct: 451 SK 452
>P24464:CP4AC_RAT Cytochrome P450 4A12 - Rattus norvegicus (Rat)| Length = 508 Score = 94.4 bits (233), Expect = 1e-18 Identities = 64/227 (28%), Positives = 100/227 (44%) Frame = +3 Query: 879 DILSFFICNDDASEHSDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDEL 1058 DIL F ++ S SD+ LR +F G DTT + +SW FY L NP +Q E+ Sbjct: 291 DIL-LFARIENGSSLSDKDLRAEVDTFMFEGHDTTASGISWIFYALATNPEHQQGCRKEI 349 Query: 1059 APIAARKKVDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIK 1238 + + D + +L M Y + E LR+YP V + + P G + Sbjct: 350 QSL-----LGDGASITWDDLDKMPYTTMCIKEALRIYPPVTAVSRMLSTPVTFPDGRSLP 404 Query: 1239 AGDKILVYSYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKE 1418 G +++ Y + VW + F P R+ + + H F+ F+ G R C+GK+ Sbjct: 405 KGITVMLSFYGLHHNPTVWPNPEV-FDPYRFAPESSRHSHS----FLPFSGGARNCIGKQ 459 Query: 1419 VAFTQMKTVAATVLWNFTLETVPGHTVKPKLSIVLHMKNGLAVTVKR 1559 A ++K A L F L P P +VL KNG+ + +K+ Sbjct: 460 FAMNELKVAVALTLLRFELLPDPTRIPIPIPRLVLKSKNGIYLRLKK 506
>Q64481:CP3AG_MOUSE Cytochrome P450 3A16 - Mus musculus (Mouse)| Length = 504 Score = 94.4 bits (233), Expect = 1e-18 Identities = 105/430 (24%), Positives = 176/430 (40%), Gaps = 19/430 (4%) Frame = +3 Query: 282 VRFFLTCDPSNVRHIFISNSINYPRGEEYADIFDVLGDGIFNADGESWRRQRAKSQLIMA 461 + F+ DP ++++ + + + ++ I A E W+R RA + Sbjct: 79 IPLFVITDPETIKNVLVKECFSVFTNRQDFFPVGIMSKSISLAKDEEWKRYRA-----LL 133 Query: 462 SPRFRSFSARCTRDKVERS---LLPFLAHAADVGARCDLHDVLLRLMFDMTCNLVFGVDP 632 SP F S + + +E+ L+ +L A+ G + DVL D+ + FGV+ Sbjct: 134 SPTFTSGNLKEMFPVIEQYGDILVKYLRQEAEKGKPVAVKDVLGAYSMDVIISTTFGVNI 193 Query: 633 GCLQIGLPSLPLARAMDDVL-----ETLFLRHVIPPACWRL--MYRYGFGPEKKMAVARR 791 L P P VL + L L + P + M P+ + ++ Sbjct: 194 DSLNN--PEDPFVENAKKVLRFDYFDPLSLSVALFPFLTPIYEMLNICMFPKDSIEFFKK 251 Query: 792 IIDRFAA---DTIVKRRYSGHKLRGEGITESSDILSFFICNDDASEHSDEFLRDTAVNLL 962 +DR D+ K R L E +S D D S+ + ++ + Sbjct: 252 FVDRMTENRLDSKQKHRVDFIYLMMEAYNKSKD-------KDSHKALSEIEITAQSIIFI 304 Query: 963 FAGRDTTGAVLSWFFYLLCENPRVEQMI---LDELAPIAARKKVDDMVVLDASELSSMVY 1133 FAG +TT ++LS+ Y L +P +++ + +DE P A D ++ ++ Y Sbjct: 305 FAGYETTSSILSFTVYSLATHPDIQKKLQEEIDEALPNKAPPTYDTVMAME--------Y 356 Query: 1134 LHAALCECLRLYPSVPITHKA--ATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDC 1307 L L E LRLYP IT++ DV +G I G +++ SY + W + Sbjct: 357 LDMVLNETLRLYP---ITNRLQRVCKKDVEINGIYIPKGSTVIIPSYVLHHDPQHWPEP- 412 Query: 1308 MEFSPERWITDD-GKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLETV 1484 EF PER+ ++ G + PY ++ F GPR C+G A MK VL NF+ + Sbjct: 413 EEFQPERFSKENKGSI---DPYVYLPFGNGPRNCIGMRFALMNMKLALIKVLQNFSFQPC 469 Query: 1485 PGHTVKPKLS 1514 + KLS Sbjct: 470 KETQIPLKLS 479
>O46051:C4D14_DROME Probable cytochrome P450 4d14 - Drosophila melanogaster (Fruit fly)| Length = 507 Score = 94.4 bits (233), Expect = 1e-18 Identities = 119/508 (23%), Positives = 215/508 (42%), Gaps = 24/508 (4%) Frame = +3 Query: 111 YYRRLQSKKTTKEE----PTEWPLLGHLLSTLANVS--NLHDWATGVLATTRYNFAAHMG 272 Y R+ + K E P +PL+G+ L N S + D ++A N M Sbjct: 18 YMRKRRHNKMYAEAGIRGPKSYPLVGNA-PLLINESPKTIFDMQFRLIAEFGKNIKTQM- 75 Query: 273 LTGVRFFLTCDPSNVRHIFISNSINYPRGEEYADIFDVLGDGIFNADGESWRRQRAKSQL 452 G F+T D + I +S+ + Y+ + + LGDG+ + G+ W R+R ++ Sbjct: 76 -LGESGFMTADSKMIEAI-MSSQQTIQKNNLYSLLVNWLGDGLLISQGKKWFRRR---KI 130 Query: 453 IMASPRFRSFSARC-TRDKVERSLLPFLAHAADVGARCDLHDVLLRLMFDMTCNLVFGVD 629 I + F+ D+ +++ L AD ++ V D+ GV Sbjct: 131 ITPAFHFKILEDFVEVFDQQSATMVQKLYDRADGKTVINMFPVACLCAMDIIAETAMGVK 190 Query: 630 PGC-LQIGLPSLPLARAMDDVLETLFLRHVIPPACWRLMYRYG-FGPE--KKMAVARRII 797 LQ P +++ L R + P RL + F P+ K+ A + + Sbjct: 191 INAQLQ---PQFTYVQSVTTASAMLAERFMNP--LQRLDFTMKLFYPKLLDKLNDAVKNM 245 Query: 798 DRFAADTIVKRRYSGHKLRGEGITESSDILS-------------FFICNDDASEHSDEFL 938 F I +RR K +G + +L+ D + S++ + Sbjct: 246 HDFTNSVITERRELLQKAIADGGDADAALLNDVGQKRRMALLDVLLKSTIDGAPLSNDDI 305 Query: 939 RDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASEL 1118 R+ +F G DTT + +++ YLL +P V+ + E+ + K + + EL Sbjct: 306 REEVDTFMFEGHDTTTSSIAFTCYLLARHPEVQARVFQEVRDVIGDDKSAPVTMKLLGEL 365 Query: 1119 SSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWG 1298 YL + E LRL+PSVPI + + + VL G I A +++ Y R + + Sbjct: 366 K---YLECVIKESLRLFPSVPIIGRYISQDTVL-DGKLIPADSNVIILIYHAQR-DPDYF 420 Query: 1299 KDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLE 1478 D +F P+R+ + + P+ + F+AGPR C+G++ A +MK+ + ++ +F L Sbjct: 421 PDPEKFIPDRFSME--RKGEISPFAYTPFSAGPRNCIGQKFAMLEMKSTISKMVRHFELL 478 Query: 1479 TVPGHTVKPKLSIVLHMKNGLAVTVKRR 1562 + G V+P L+++L G+ +K R Sbjct: 479 PL-GEEVQPVLNVILRSTTGINCGLKPR 505
>P14581:CP4A7_RABIT Cytochrome P450 4A7 precursor - Oryctolagus cuniculus (Rabbit)| Length = 511 Score = 94.0 bits (232), Expect = 2e-18 Identities = 72/279 (25%), Positives = 119/279 (42%), Gaps = 7/279 (2%) Frame = +3 Query: 744 YRYGFGPEKKMAVARRIIDRFAADTIVKRRYSG-------HKLRGEGITESSDILSFFIC 902 + Y PE +++ + D ++++R + K+R + + D+L F Sbjct: 242 FLYRLSPEGRLSHRACQLAHEHTDRVIQQRKAQLQQEGELEKVRRKRRLDFLDVL-LFAK 300 Query: 903 NDDASEHSDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKK 1082 ++ S SD+ LR +F G DTT + +SW FY L +P + +E+ + Sbjct: 301 MENGSSLSDQDLRAEVDTFMFEGHDTTASGISWIFYALATHPEHQHRCREEIQGL----- 355 Query: 1083 VDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVY 1262 + D + L M Y + E LRLYP VP + P G + G I + Sbjct: 356 LGDGASITWEHLDKMPYTTMCIKEALRLYPPVPGVGSKLSSPVTFPDGRSLPKGIIITLS 415 Query: 1263 SYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKT 1442 Y + VW + F P R+ G RH + F+ F+ G R C+GK+ A ++K Sbjct: 416 IYGLHHNPKVWPNPEV-FDPSRFAP--GSARHS--HAFLPFSGGSRNCIGKQFAMNELKV 470 Query: 1443 VAATVLWNFTLETVPGHTVKPKLSIVLHMKNGLAVTVKR 1559 A L F L P P +VL KNG+ + +++ Sbjct: 471 AVALTLVRFELLPDPTRVPIPITRLVLKSKNGIHLRLRK 509
>Q9JMA7:CP341_MOUSE Cytochrome P450 3A41 - Mus musculus (Mouse)| Length = 504 Score = 94.0 bits (232), Expect = 2e-18 Identities = 116/505 (22%), Positives = 199/505 (39%), Gaps = 20/505 (3%) Frame = +3 Query: 60 SMEHWYWFVGLVCCFLSYYRRLQS--KKTTKEEPTEWPLLGHLLSTLANVSNLHDWATGV 233 S++ W ++ Y R KK PT P LG +L+ + W + Sbjct: 8 SLDTWVLLAIILVLLYRYGTRTHGLFKKQGIPGPTPLPFLGTVLNYYKGL-----WKFDM 62 Query: 234 LATTRYNFAAHMGLTGVRFFLTCDPSNVRHIFISNSIN-YPRGEEYADIFDVLGDGIFNA 410 +Y + + F+ DP ++++ + + + E+ + ++ I + Sbjct: 63 ECYEKYGKTWGLFDGQMPLFVITDPEMIKNVLVKECFSVFTNRREFGPV-GIMSKAISIS 121 Query: 411 DGESWRRQRAKSQLIMASPRFRSFSARCTRDKVERS---LLPFLAHAADVGARCDLHDVL 581 E W+R RA + SP F S + +E+ L+ +L A+ G + DVL Sbjct: 122 KDEEWKRYRA-----LLSPTFTSGKLKEMFPVIEQYGDILVKYLMQEAEKGKPVTMKDVL 176 Query: 582 LRLMFDMTCNLVFGVDPGCLQIGLPSLPLARAMDDVL-----ETLFLRHVIPPACWRL-- 740 D+ + FGV+ L P P +L + L V+ P + Sbjct: 177 GAYSIDVITSTSFGVNVDSLNN--PEDPFVEKAKGILRVDFFDPLVFSVVLFPFLTPVYE 234 Query: 741 MYRYGFGPEKKMAVARRIIDRFAA---DTIVKRRYSGHKLRGEGITESSDILSFFICNDD 911 M P+ + ++ ++R D+ K R +L S D D Sbjct: 235 MLNICMFPKDSIEFFKKFVNRMKESRLDSKQKHRVDFLQLMMNAHNNSKD-------KDS 287 Query: 912 ASEHSDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMI---LDELAPIAARKK 1082 SD + ++ +FAG +TT + LS+ Y L +P +++ + +DE P A Sbjct: 288 HKALSDMEITAQSIVFIFAGYETTSSTLSFTLYCLATHPDIQKKLQEEIDETLPNKAPPT 347 Query: 1083 VDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVY 1262 D ++ M YL L E LRLYP + + DV +G I G +++ Sbjct: 348 YDTVM--------EMEYLDMVLNETLRLYP-IGNRLERFCKKDVELNGVYIPKGSTVMIP 398 Query: 1263 SYSMGRMEGVWGKDCMEFSPERWITDD-GKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMK 1439 SY++ W + EF PER+ ++ G + PY ++ F GPR C+G AF MK Sbjct: 399 SYALHHDPQHWPEP-EEFQPERFSKENKGSI---DPYLYMPFGIGPRNCIGMRFAFMTMK 454 Query: 1440 TVAATVLWNFTLETVPGHTVKPKLS 1514 V+ NF+ + + KLS Sbjct: 455 LALTKVMQNFSFQPCQETQIPLKLS 479
>Q27606:CP4E2_DROME Cytochrome P450 4e2 - Drosophila melanogaster (Fruit fly)| Length = 526 Score = 93.6 bits (231), Expect = 2e-18 Identities = 104/439 (23%), Positives = 178/439 (40%), Gaps = 46/439 (10%) Frame = +3 Query: 387 LGDGIFNADGESWRRQRAKSQLIMASPRFRSFSARCTRDKVERSLLPFLAHAADVGARCD 566 LG G+ + G W + R M +P F + + + + F+ H V A + Sbjct: 112 LGLGLLTSTGSKWHKHRK-----MITPAFHFNILQDFHEVMNENSTKFIKHLKTVAAGDN 166 Query: 567 LHDVLLR---LMFDMTCNLVFGVDPGCLQIGLPSLPLARAMDDVLETLFLRHVIPPACWR 737 + D + L D+ C+ GV ++ S+ +A D+ + +R P Sbjct: 167 IFDFQEQAHYLTLDVICDTAMGVSINAMENRSSSI--VQAFKDMCYNINMRAFHPLKRNE 224 Query: 738 LMYRYGFGPEKKMAVARRIIDRFAADTIVKRRYSGHKLRGEGITESSD------------ 881 L+YR + + D + I+ +R HK G T + D Sbjct: 225 LLYRLAPDYPAYSRTLKTLQD--FTNEIIAKRIEAHK-SGAVSTNAGDEFTRKKMAFLDT 281 Query: 882 ILSFFICNDDASEHSDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELA 1061 +LS I D + + L + +F G DTT + +S+ YLL + ++ + E Sbjct: 282 LLSSTI---DGRPLNSKELYEEVSTFMFEGHDTTTSGVSFAVYLLSRHQDEQRKLFKEQR 338 Query: 1062 PIAARKKVDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKA 1241 + ++ E+S M YL + E R+YPSVP + T D + G + Sbjct: 339 EVMGNSELGRDATFQ--EISQMKYLDLFIKEAQRVYPSVPFIGRF-TEKDYVIDGDLVPK 395 Query: 1242 GDKILVYSYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEV 1421 G + + +G E V+ KD +F PER+ +L P++++ F+AGPR C+G++ Sbjct: 396 GTTLNLGLVMLGYNEKVF-KDPHKFRPERF-----ELEKPGPFEYVPFSAGPRNCIGQKF 449 Query: 1422 AFTQMKTVAATVLWNFTLETVPG-----------------------------HTVKPKLS 1514 A ++KTV + ++ NF E +P H P LS Sbjct: 450 ALLEIKTVVSKIIRNF--EVLPALDELVSKDGYISTTIGLPDAERKKRDPYRHKYDPILS 507 Query: 1515 IVLHMK--NGLAVTVKRRN 1565 VL +K NGL + +K R+ Sbjct: 508 AVLTLKSENGLYIRLKERH 526
>P14580:CP4A6_RABIT Cytochrome P450 4A6 precursor - Oryctolagus cuniculus (Rabbit)| Length = 510 Score = 93.6 bits (231), Expect = 2e-18 Identities = 71/281 (25%), Positives = 119/281 (42%), Gaps = 11/281 (3%) Frame = +3 Query: 750 YGFGPEKKMAVARRIIDRFAADTIVKRRYSG-------HKLRGEGITESSDILSFFICND 908 Y PE +++ + D ++++R + K+R + + D+L F + Sbjct: 243 YRLSPEGRLSHRACQLAHEHTDRVIQQRKAQLQQEGELEKVRRKRRLDFLDVL-LFAKME 301 Query: 909 DASEHSDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVD 1088 + S SD+ LR +F G DTT + +SW FY L +P + +E+ + + Sbjct: 302 NGSSLSDQDLRAEVDTFMFEGHDTTASGISWIFYALATHPEHQHRCREEIQGL-----LG 356 Query: 1089 DMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSY 1268 D + L M Y + E LRLYP VP + + P G + G + + Y Sbjct: 357 DGASITWEHLDQMPYTTMCIKEALRLYPPVPGVGRQLSSPVTFPDGRSLPKGVIVTLSIY 416 Query: 1269 SMGRMEGVWGK----DCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQM 1436 ++ VW D F+P G RH + F+ F+ GPR C+GK+ A ++ Sbjct: 417 ALHHNPKVWPNPEVFDPFPFAP-------GSARHS--HAFLPFSGGPRNCIGKQFAMNEL 467 Query: 1437 KTVAATVLWNFTLETVPGHTVKPKLSIVLHMKNGLAVTVKR 1559 K A L F L P K +VL NG+ + +++ Sbjct: 468 KVAVALTLVRFELLPDPKRVPDQKPRLVLKSSNGIHLRLRK 508
>Q9T0K2:C71AK_ARATH Cytochrome P450 71A20 - Arabidopsis thaliana (Mouse-ear cress)| Length = 495 Score = 93.6 bits (231), Expect = 2e-18 Identities = 105/459 (22%), Positives = 186/459 (40%), Gaps = 12/459 (2%) Frame = +3 Query: 90 LVCCFLSYYRRLQSKKTTKEEPTEW--PLLGHLLSTLANVSNLHDWATGVLATTRYN--F 257 L+ L + + K P+ W P++G+L + +LH + + RY Sbjct: 11 LLALLLKSILKRTATKNFNLPPSPWRLPVIGNL-----HQLSLHTHRSLRSLSLRYGPLM 65 Query: 258 AAHMGLTGVRFFLTCDPSN-VRHIFISNSINYPRGEEYADIFDVLGDGIFNADGESWRRQ 434 H G T V + D ++ V N P+ + I D F GE WR+ Sbjct: 66 LLHFGRTPVLIVSSADVAHDVMKTHDLVCANRPKTKVVDKILSGGRDVAFAPYGEYWRQM 125 Query: 435 RA-------KSQLIMASPRFRSFSARCTRDKVERSLLPFLAHAADVGARCDLHDVLLRLM 593 ++ ++++ + + R + +K+E+ A + + +L +L+ L Sbjct: 126 KSICIQNLLNNKMVRSYEKIREEEIKRMIEKLEK------ASCSSSPSPVNLSQILMTLT 179 Query: 594 FDMTCNLVFGVDPGCLQIGLPSLPLARAMDDVLETLFLRHVIPPACWRLMYRYGFGPEKK 773 D+ C + G + G+ + R +L + IP W R G + K Sbjct: 180 NDIICRVALGRKYSGKKDGIDVENIVRTFAALLGEFPVGEYIPSLSWIDRIR---GLDHK 236 Query: 774 MAVARRIIDRFAADTIVKRRYSGHKLRGEGITESSDILSFFICNDDASEHSDEFLRDTAV 953 M V + D F + + + + R + + + +L+ E L+ Sbjct: 237 MEVVDKRFDEFLERVVKEHEEADKETRSDLVDK---LLTIQSDKTGQFELEKSALKLIIW 293 Query: 954 NLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVY 1133 ++ AG TT + L W L NP+V + + +E+ + + D+ V + E M Y Sbjct: 294 DMFLAGTATTLSFLEWAMTELMRNPKVMKKLQEEIRSSSPQ----DLFVTE-KEAEKMNY 348 Query: 1134 LHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCME 1313 L A + E LRL P P+ DV G+ I AG +++V ++++ R WG D E Sbjct: 349 LQAVIKEALRLRPPAPLLVPRVLSEDVKLKGYNIPAGTQVIVNAWAIQRDTTTWGTDAEE 408 Query: 1314 FSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFT 1430 F PER + + + Q +KFI F +G R C G + FT Sbjct: 409 FKPERHLDTNLDFQGQ-DFKFIPFGSGKRICPG--IGFT 444
>O23365:C97B3_ARATH Cytochrome P450 97B3 - Arabidopsis thaliana (Mouse-ear cress)| Length = 580 Score = 93.2 bits (230), Expect = 3e-18 Identities = 106/470 (22%), Positives = 186/470 (39%), Gaps = 44/470 (9%) Frame = +3 Query: 288 FFLTCDPSNVRHIFISNSINYPRGEEYADIFDVLGDGIFNADGESWR-RQRAKSQL---I 455 F + DP RH+ N+ +Y +G + ++G G+ AD ++W+ R+RA + + Sbjct: 123 FVVISDPIIARHVLRENAFSYDKGVLAEILEPIMGKGLIPADLDTWKLRRRAITPAFHKL 182 Query: 456 MASPRFRSFSARCTRD---KVERSLLPFLAHAADVGARCDLHDVLLRLMFDMTCNLVFGV 626 + FS C+ K E+ + + + DL L D+ VF Sbjct: 183 YLEAMVKVFSD-CSEKMILKSEKLIREKETSSGEDTIELDLEAEFSSLALDIIGLSVFNY 241 Query: 627 DPGCLQIGLPSLPLARAMDDVL------ETLFLRHV-IPPACWRLMYRYGFGPEKKMAVA 785 D G + P+ +A+ L T + + PPA W + + F + K + Sbjct: 242 DFGSVT---KESPVIKAVYGTLFEAEHRSTFYFPYWNFPPARWIVPRQRKFQSDLK--II 296 Query: 786 RRIIDRFAADTIVKRRYSG-HKLRGEGITESSDI-LSFFICNDDASEHSDEFLRDTAVNL 959 +D + R+ + KL+ T D L F+ + + D LRD + + Sbjct: 297 NDCLDGLIQNAKETRQETDVEKLQERDYTNLKDASLLRFLVDMRGVDIDDRQLRDDLMTM 356 Query: 960 LFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLH 1139 L AG +TT AVL+W +LL +NP + E+ + + + + Y+ Sbjct: 357 LIAGHETTAAVLTWAVFLLSQNPEKIRKAQAEIDAVLGQGPP------TYESMKKLEYIR 410 Query: 1140 AALCECLRLYPSVPITHKAATHNDVLP-------SGHEIKAGDKILVYSYSMGRMEGVWG 1298 + E LRL+P P+ + + LP GH++ G I + Y++ R W Sbjct: 411 LIVVEVLRLFPQPPLLIRRTLKPETLPGGHKGEKEGHKVPKGTDIFISVYNLHRSPYFWD 470 Query: 1299 KDCMEFSPERWITD------DGKLRHQP--------------PYKFIAFNAGPRTCLGKE 1418 +F PER++ +G P + F+ F GPR C+G + Sbjct: 471 NP-HDFEPERFLRTKESNGIEGWAGFDPSRSPGALYPNEIIADFAFLPFGGGPRKCIGDQ 529 Query: 1419 VAFTQMKTVAATVLWNFTLE-TVPGHTVKPKLSIVLHMKNGLAVTVKRRN 1565 A + A + F +E +V+ +H KNG+ +KRR+ Sbjct: 530 FALMESTVALAMLFQKFDVELRGTPESVELVSGATIHAKNGMWCKLKRRS 579
>Q9VLZ7:C4D21_DROME Probable cytochrome P450 4d21 - Drosophila melanogaster (Fruit fly)| Length = 511 Score = 93.2 bits (230), Expect = 3e-18 Identities = 109/435 (25%), Positives = 187/435 (42%), Gaps = 24/435 (5%) Frame = +3 Query: 330 ISNSINYPRGEEYADIFDVLGDGIFNADGESWRRQRAKSQLIMASPRFRSFSARCTRDKV 509 +S+S + Y + D LGDG+ + G W +R + +P +F +C + V Sbjct: 93 LSSSTLLKKAHLYRFLRDFLGDGLLLSTGNKWTSRRK-----VLAP---AFHFKCLENFV 144 Query: 510 ERS------LLPFLAHAADVGARCDLHDVLLRLMFDMTCNLVFGVDPGCLQIGLPSLPLA 671 E ++ L + AD DL + D+T GV P+ P Sbjct: 145 EIMDRNSGIMVEKLKNYADGKTCVDLFKFVSLEALDVTTETAMGVQVNAQNE--PNFPYT 202 Query: 672 RAMDDV-------LETLFLRHV-IPPACWRLMYR---------YGFGPEKKMAVARRIID 800 +A+ V L ++ +R+ + P L+YR F +K + R I++ Sbjct: 203 KALKSVVYIESKRLASVSMRYNWLFPLAAPLVYRRLQKDIAIMQDF-TDKVIRERRAILE 261 Query: 801 RFAADTIVKRRYSGHK-LRGEGITESSDILSFFICNDDASEHSDEFLRDTAVNLLFAGRD 977 R AD K G + G+ DIL D SD +R+ +FAG D Sbjct: 262 RARADGTYKPLIMGDDDIGGKAKMTLLDIL--LQATIDNKPLSDVDIREEVDVFIFAGDD 319 Query: 978 TTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAALCEC 1157 TT + +S + + +P+V++ I +EL + D + ++L + YL + E Sbjct: 320 TTTSGVSHALHAISRHPKVQECIYEELVSVLGP---DPDASVTQTKLLELKYLDCVIKET 376 Query: 1158 LRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWIT 1337 +RL+P VPI + D+ I IL+ Y + R + + D + F PERW+ Sbjct: 377 MRLHPPVPILGRYIPE-DLKIGEITIPGNTSILLMPYYVYR-DPEYFPDPLVFKPERWM- 433 Query: 1338 DDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLETVPGHTVKPKLSI 1517 D + PP +I F++GP+ C+G++ A QMK + + V+ ++ L + G +K + Sbjct: 434 DMKTTSNTPPLAYIPFSSGPKNCIGQKFANLQMKALISKVIRHYELLPL-GADLKATYTF 492 Query: 1518 VLHMKNGLAVTVKRR 1562 +L G V +K R Sbjct: 493 ILSSSTGNNVGLKPR 507
>P82713:CP392_DROME Probable cytochrome P450 309a2 - Drosophila melanogaster (Fruit fly)| Length = 538 Score = 92.8 bits (229), Expect = 4e-18 Identities = 99/416 (23%), Positives = 174/416 (41%), Gaps = 24/416 (5%) Frame = +3 Query: 294 LTCDPSNVRHIFISNS-----------INYPRGEEYADIFDVLGDGIFNADGESWRRQRA 440 L DP + +SN + + + ++YA + F A G+SWRR R Sbjct: 117 LVLDPELAHEVLVSNFRCYKDSLQSSYLRHAKWDKYARL------NPFWASGQSWRRLRT 170 Query: 441 KSQLIMASPRFRSFSARCTRDKVERSLLPFLAH-AADVGARCDLHDVLLRLMFDMTCNLV 617 +Q ++ R R A ++ + L ++ A+ + D+ R + + + Sbjct: 171 DAQAGISGSRLRQ--AYNIWEQGGQMLTEYMTQQVAEKNNILETRDLCFRYTAHVMADFI 228 Query: 618 FGVDPGCLQIGLPSLPLARAMDD-------VLETLFLRHVIPPACWRLMYRYGFGPEKKM 776 +G+D G L + + M + TLF+ ++ P C RL+ R+ F P++ Sbjct: 229 WGIDAGTLTRPMEQPNKVQEMASKWTSYAFYMLTLFMATIVAP-CSRLLLRFRFYPKE-- 285 Query: 777 AVARRIIDRFAADTIVKRRYSGHKLRGEGITESSDILSFFICNDDASEHSDEFLRDTAVN 956 ++I R +G R +D LS + D + + + L A+ Sbjct: 286 --TDEFFSNLTKESIELRLKAGDSTR-------TDYLSHLLQLRDQKQATHDDLVGHALT 336 Query: 957 LLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYL 1136 ++ G DT+G L Y L ENP V+Q + E+ A +K LD +LSS+ YL Sbjct: 337 VMLDGYDTSGTALLHALYYLAENPAVQQKLRVEILSCMASEK-----SLDFEKLSSLQYL 391 Query: 1137 HAALCECLRLYPSVPITHKAATHNDVL----PSGHEIKAGDKILVYSYSMGRMEGVWGKD 1304 + E LRL +P K T V+ +++ G I++ +Y + + + Sbjct: 392 EQVIYESLRLSSLIPQYTKVCTLPTVIRLSESKSLDVEVGMTIMIPNYQF-HHDKQYFPE 450 Query: 1305 CMEFSPERWITDDGKLRH-QPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNF 1469 F PER+ D+G + F+ F+ GPR C+G +A +K+ +L NF Sbjct: 451 PEAFKPERF--DNGAYQELMRKGIFLPFSDGPRICMGVPLAMLTLKSALVHILSNF 504
>O49858:C82A3_SOYBN Cytochrome P450 82A3 - Glycine max (Soybean)| Length = 527 Score = 92.8 bits (229), Expect = 4e-18 Identities = 67/249 (26%), Positives = 116/249 (46%), Gaps = 10/249 (4%) Frame = +3 Query: 759 GPEKKMAVARRIIDRFAADTIVKRRYSGHKLRGEGITESSDILSFFICNDDASE----HS 926 G EK M + +D+ ++ + + R KL GE + D + I + ++ + Sbjct: 252 GHEKAMKANAKEVDKLLSEWLEEHRQK--KLLGENVESDRDFMDVMISALNGAQIGAFDA 309 Query: 927 DEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLD 1106 D + T++ L+ G D+T L+W LL NP LA A++++D + D Sbjct: 310 DTICKATSLELILGGTDSTAVTLTWALSLLLRNP---------LALGKAKEEIDMQIGKD 360 Query: 1107 A----SELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSM 1274 S++S +VYL A + E LRLYP P + + + G+ IK G +++ + + Sbjct: 361 EYIRESDISKLVYLQAIVKETLRLYPPAPFSSPREFTENCILGGYHIKKGTRLIHNLWKI 420 Query: 1275 GRMEGVWGKDCMEFSPERWIT--DDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVA 1448 R VW D +EF PER++T D LR ++ + F +G R C G + + Sbjct: 421 HRDPSVW-SDPLEFKPERFLTTHKDVDLRGH-NFELLPFGSGRRVCAGMSLGLNMVHFTL 478 Query: 1449 ATVLWNFTL 1475 A +L +F + Sbjct: 479 ANLLHSFDI 487
>Q05047:C72A1_CATRO Cytochrome P450 72A1 - Catharanthus roseus (Rosy periwinkle)| (Madagascar periwinkle) Length = 524 Score = 92.8 bits (229), Expect = 4e-18 Identities = 57/199 (28%), Positives = 97/199 (48%) Frame = +3 Query: 963 FAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHA 1142 FAG++TTG +L+W LL ++P ++ +E+ + K + L+ + Y+ Sbjct: 331 FAGQETTGVLLTWTTILLSKHPEWQERAREEVLQAFGKNKPE------FERLNHLKYVSM 384 Query: 1143 ALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSP 1322 L E LRLYP V I H D + I AG ++++ + + R + +WG+D MEF+P Sbjct: 385 ILYEVLRLYPPV-IDLTKIVHKDTKLGSYTIPAGTQVMLPTVMLHREKSIWGEDAMEFNP 443 Query: 1323 ERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLETVPGHTVK 1502 R++ D + ++ F+ GPR CLG+ A Q K A +L F + P + Sbjct: 444 MRFV-DGVANATKNNVTYLPFSWGPRVCLGQNFALLQAKLGLAMILQRFKFDVAPSYVHA 502 Query: 1503 PKLSIVLHMKNGLAVTVKR 1559 P + + + G V K+ Sbjct: 503 PFTILTVQPQFGSHVIYKK 521
>Q09653:C13AA_CAEEL Putative cytochrome P450 CYP13A10 - Caenorhabditis elegans| Length = 519 Score = 92.8 bits (229), Expect = 4e-18 Identities = 117/500 (23%), Positives = 194/500 (38%), Gaps = 41/500 (8%) Frame = +3 Query: 102 FLSYYRRLQS--KKTTKEEPTEWPLLGHLLSTLAN----VSNLHDWATGVLATTRYNFAA 263 F+SYY + + ++ P +PL+G TL + + DW L Y + Sbjct: 15 FISYYLWIWTYWRRRGIPGPLGYPLVGSFPKTLKSEYPQYLQIRDWTK--LYGPIYGYTE 72 Query: 264 HMGLTGVRFFLTCDPSNVRHIFISNSINYPRGEEYADIFDVLGD-------GIFNADGES 422 ++ + D VR IF+ N+ + + + GD +F+A G Sbjct: 73 GT----IKTLIVSDIDIVRQIFVEQYDNFYGRK----LNPIQGDPEKDERTNLFSAQGFR 124 Query: 423 WRRQRAKSQLIMASPRFRSFSARCTRDKVERSLLPFLAHAADV---GARCDLHDVLLRLM 593 W+R RA ++SP F + S R VE S + L H + G + D+ Sbjct: 125 WKRLRA-----ISSPTFSNNSLRKINVTVEDSAMELLRHIEEQTSEGQQIDMLQFYQEFT 179 Query: 594 FDMTCNLVFGVDPGCLQIGLPSLPLARAM--DDVLETLFLRHVIPPACWRLMYRYGFGPE 767 D + G + P L RA+ D+ + V P ++R+ Sbjct: 180 MDTIGRIAMGQTDSQM-FKNPLLKFVRAIFGDNRKHIPLIGGVFPTLAQ--VFRFFMLKF 236 Query: 768 KKMAVARRIIDRFAADTIVKRRYS---GHKLRGEGITESSDILSFFI-CNDDASEHSDEF 935 + A I T V+ R + G I E D + F+ D EH E Sbjct: 237 PLLGAANFIHVNKTVVTAVQNRIDQRENDRKNGIEIGEPQDFIDLFLEARADDVEHFQEN 296 Query: 936 LRDTAVN-------------------LLFAGRDTTGAVLSWFFYLLCENPRVEQMILDEL 1058 D + L AG DTT LS+ +LL +P V++ + +E+ Sbjct: 297 NGDFSKTSSYGNRQLTTQEIVGQCLVFLIAGFDTTALSLSYTTFLLATHPEVQKKLQEEI 356 Query: 1059 APIAARKKVDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIK 1238 R+ ++ + D LS + Y+ + E LRLYP + + E++ Sbjct: 357 E----RECIEPSISFD--HLSKLKYMDCIIKETLRLYPLGTMANSRRCMRATKLGNVEVE 410 Query: 1239 AGDKILVYSYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKE 1418 G + V ++S+ +WG D EF PERW+ + Q +I+F GPR C+G Sbjct: 411 VGTMVQVDTWSLHTDTKIWGDDAKEFKPERWLDPNCDQVFQKG-GYISFGLGPRQCVGMR 469 Query: 1419 VAFTQMKTVAATVLWNFTLE 1478 +A+ + K + A +L +T E Sbjct: 470 LAYMEEKMLLAHILRKYTFE 489
>O44221:CP4E5_DROMT Cytochrome P450 4e5, mitochondrial precursor - Drosophila mettleri| (Fruit fly) Length = 522 Score = 92.4 bits (228), Expect = 5e-18 Identities = 92/407 (22%), Positives = 167/407 (41%), Gaps = 20/407 (4%) Frame = +3 Query: 309 SNVRHIFISNSINYPRGEEYADIFDVL----GDGIFNADGESWRRQRAKSQLIMASPRFR 476 SN +H+ + +N E DI+D+L G+G+ + G W + R M +P F Sbjct: 83 SNPKHLEVI--MNSTTLIEKLDIYDMLHPWLGEGLLTSKGSKWHKHRK-----MITPTFH 135 Query: 477 SFSARCTRDKVERSLLPFLAHAADVGAR---CDLHDVLLRLMFDMTCNLVFGVDPGCLQI 647 + + + F+ +V A D D L D C+ GV ++ Sbjct: 136 FNILQDFHQVMNENSAKFIKRLKEVSAGDNIIDFQDETHYLTLDAICDTAMGVTINAIE- 194 Query: 648 GLPSLPLARAMDDVLETLFLRHVIPPACWRLMYRYGFGPE-KKMAVARRIIDRFAADTIV 824 ++ + +A D+ + +R P R + Y F PE A + + F D I Sbjct: 195 KRDTVDVVKAFKDMCHIINMRAFRP--LQRSDFLYRFSPEYATYAKTLKTLKDFTNDIIA 252 Query: 825 KR----RYSGHKLRGEGITESSDIL---SFFICNDDASEHSDEFLRDTAVNLLFAGRDTT 983 KR R + K EG S + + D + + + + +F G DTT Sbjct: 253 KRIKVHRTAAAKTNQEGSEFSRKKMLPDTLLSATIDGRPLNQQEIYEEVSTFMFEGHDTT 312 Query: 984 GAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAALCECLR 1163 + +++ Y+L P ++ + +E + + D E+S+M YL + E R Sbjct: 313 TSGVAFAGYILSRFPEEQRKLYEEQQAVMGNELNRDATF---QEISAMKYLDLFIKEAQR 369 Query: 1164 LYPSVPITHKAAT-----HNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPER 1328 +YPSVP + H ++P G + G +L Y D + P R Sbjct: 370 VYPSVPFIGRYTDKDYNIHGTIMPKGTTLNLGIIVLGYD------------DRVFEEPHR 417 Query: 1329 WITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNF 1469 + + + + P++++ F+AGPR C+G++ A ++KTV + ++ F Sbjct: 418 FYPERFEKQKPGPFEYVPFSAGPRNCIGQKFALLELKTVISKLVRTF 464
>Q43078:C97B1_PEA Cytochrome P450 97B1 - Pisum sativum (Garden pea)| Length = 552 Score = 92.4 bits (228), Expect = 5e-18 Identities = 108/441 (24%), Positives = 172/441 (39%), Gaps = 48/441 (10%) Frame = +3 Query: 288 FFLTCDPSNVRHIFISNSINYPRGEEYADIFD-VLGDGIFNADGESWRRQRA-------K 443 F + DP RHI N+ +Y +G ADI + ++G G+ AD E+W+++R Sbjct: 127 FVVVSDPIVARHILRENAFSYDKGV-LADILEPIMGKGLIPADLETWKQRRRVIAPGFHT 185 Query: 444 SQLIMASPRFRSFSARCTRDKVERSLLPFLAHAADVGARCDLHDVLLRLMFDMTCNLVFG 623 S L F S S R E LL DL L ++ VF Sbjct: 186 SYLEAMVQLFTSCSERTVLKVNE--LLEGEGRDGQKSVELDLEAEFSNLALEIIGLGVFN 243 Query: 624 VDPGCLQIGLPSLPLARAMDDVLETLFLRHVIPPACWRLMYRYGFGPEKK-----MAVAR 788 D G + P+ +A+ L R W+ P ++ + V Sbjct: 244 YDFGSVT---NESPVIKAVYGTLFEAEHRSTFYIPYWKFPLARWIVPRQRKFQDDLKVIN 300 Query: 789 RIIDRFAADTIVKRRYSG-HKLRGEGITESSDI-LSFFICNDDASEHSDEFLRDTAVNLL 962 +D + R+ + KL+ + D L F+ + + D LRD + +L Sbjct: 301 TCLDGLIRNAKESRQETDVEKLQQRDYSNLKDASLLRFLVDMRGVDVDDRQLRDDLMTML 360 Query: 963 FAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHA 1142 AG +TT AVL+W +LL +NP + E+ + K + L + Y+ Sbjct: 361 IAGHETTAAVLTWAVFLLAQNPDKMKKAQAEVDLVLGMGKPTFEL------LKKLEYIRL 414 Query: 1143 ALCECLRLYPSVPITHKAATHNDVLPSGHE-------IKAGDKILVYSYSMGRMEGVWGK 1301 + E LRLYP P+ + + DVLP GH+ I AG + + Y++ R W + Sbjct: 415 IVVETLRLYPQPPLLIRRSLKPDVLPGGHKGDKDGYTIPAGTDVFISVYNLHRSPYFWDR 474 Query: 1302 DCMEFSPERWITD------DGKLRHQP--------------PYKFIAFNAGPRTCLGKEV 1421 +F PER++ +G P + F+ F GPR C+G + Sbjct: 475 P-NDFEPERFLVQNNNEEVEGWAGFDPSRSPGALYPNEIISDFAFLPFGGGPRKCVGDQ- 532 Query: 1422 AFTQMKTVAATV------LWN 1466 F M++ A V +WN Sbjct: 533 -FALMESTVALVCCYRISMWN 552
>O65787:C71B6_ARATH Cytochrome P450 71B6 - Arabidopsis thaliana (Mouse-ear cress)| Length = 503 Score = 92.4 bits (228), Expect = 5e-18 Identities = 120/498 (24%), Positives = 204/498 (40%), Gaps = 10/498 (2%) Frame = +3 Query: 78 WFVGLVCCFLSYYRRLQSKKTTKEEPTEWPLLG--HLLSTLANVSNLHDWATGVLATTRY 251 W + L+ L + L+S K P P+LG H L +L + S L D + +Y Sbjct: 15 WLLLLLIPPLLIFFLLRSPKNLPPGPPRLPILGNIHQLGSLPHRS-LRD------LSLKY 67 Query: 252 NFAAHMGLTGVRFFLTCDPSNVRHIFI---SNSINYPRGEEYADIF-DVLGDGIFNADGE 419 + L VR + P + S P+ F D LG G F G+ Sbjct: 68 GPVITVYLGSVRTVVVHSPETAEEVLKLHDSECCTRPKLSITKSFFYDGLGLG-FTKWGD 126 Query: 420 SWRRQRAKSQLIMASPRFRSFSARCTRDKVERSLLPFLAHAADVGARCDLHDVLLRLMFD 599 +R R L + S + R+ S R R++ L+ + +A G+ DL L + + Sbjct: 127 YYRDVRKLCVLELFSVK-RANSFRNIREEELSRLVNSFSDSASSGSSVDLTANLAKFVAS 185 Query: 600 MTCNLVFGVD-PGCLQIGLPSLPLARAMDDVLETLFLRHVIPPACWRLMYRYGFGPEKKM 776 TC + FG+ G L L + V+ + P W L G ++ Sbjct: 186 FTCRMAFGLSFQGSGMDNETFLELFTEANRVIGKFAAADIFPGFGWILDRISGLDSSRRK 245 Query: 777 AVARRIIDRFAADTIVKRRYSGHKLRGEGITESSDILSFFICNDD---ASEHSDEFLRDT 947 + + +D F IV R K + E + D+L + +S +D +R Sbjct: 246 SF--QDLDTFYQKAIVDHR---EKKKTEDREDLIDVLLKLQSQETKLGSSRITDTHIRAI 300 Query: 948 AVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSM 1127 ++L AG DT+ L W L +PRV + + E+ R+ V D ++ +L ++ Sbjct: 301 IMDLFVAGVDTSVITLDWTMAELSRHPRVMKKVQAEI-----REHVGDKGIVTYDDLEAL 355 Query: 1128 VYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDC 1307 VY+ + E RL+ PI + G++I G +I V ++++GR VW KD Sbjct: 356 VYMKMVIKETWRLHAPSPILIPREAMTNFKIKGYDIYPGTRIHVNAWAIGRNPDVW-KDP 414 Query: 1308 MEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLETVP 1487 EF PER++ D ++ + F +G R C V + ++ A +L++F + Sbjct: 415 DEFIPERFV-DSNVETKGTSFELLPFGSGRRGCPAMYVGLSTVEYTLANLLYHFDWKATE 473 Query: 1488 GHTVKPKLSIVLHMKNGL 1541 +V+ + H K+ L Sbjct: 474 EVSVEEAPGLTSHRKHPL 491
>Q9VMS7:C4AC3_DROME Probable cytochrome P450 4ac3 - Drosophila melanogaster (Fruit fly)| Length = 509 Score = 91.7 bits (226), Expect = 9e-18 Identities = 92/393 (23%), Positives = 172/393 (43%), Gaps = 5/393 (1%) Frame = +3 Query: 312 NVRHIFISNSINYPRGEEYADIFDVLGDGIFNADGESWRRQRAKSQLIMASPRFRSFSAR 491 + IF S I + Y I LGDG+ + + W +R +SF + Sbjct: 103 DAEEIFQSTKIT-TKNMSYELIRPFLGDGLLISIDQKWHTRRKTLTPAFHFNILQSFLSI 161 Query: 492 CTRDKVERSLLPFLAHAADVGARCDLHDVLLRLMFDMTCNLVFGVDPGCLQIGLPSLPLA 671 + + + L +VG +L+ ++ + + C GV + G Sbjct: 162 FKEES--KKFIKILDK--NVGFELELNQIIPQFTLNNICETALGVKLDDMSEGNE---YR 214 Query: 672 RAMDDVLETLFLRHVIPPACWRLMYRYGFGPEKKMAVARRIIDRFAADTIVKRRYS-GHK 848 +A+ D E +F + + P + Y + FG KK + R I F++ I ++R K Sbjct: 215 KAIHD-FEIVFNQRMCNPLMFFNWYFFLFGDYKKYSRILRTIHGFSSGIIQRKRQQFKQK 273 Query: 849 LRGE----GITESSDILSFFICNDDASEHSDEFLRDTAVNLLFAGRDTTGAVLSWFFYLL 1016 G+ G + +L + + + + + D +F G DTT L + LL Sbjct: 274 QLGQVDEFGKKQRYAMLDTLLAAEAEGKIDHQGICDEVNTFMFGGYDTTSTSLIFTLLLL 333 Query: 1017 CENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKA 1196 + V++ +EL + + +D++ + +EL ++L + E LRL+PS PI + Sbjct: 334 ALHADVQERCYEELQDLP--EDIDEVSMFQFNEL---IHLECVIKESLRLFPSAPIIGRT 388 Query: 1197 ATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKF 1376 V+ +G + +I ++ Y + R + K +F PER++ ++ RH P+ F Sbjct: 389 CIEESVM-NGLVLPKNAQISIHIYDIMRDARHFPKP-NQFLPERFLPENSVNRH--PFAF 444 Query: 1377 IAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTL 1475 + F+AGPR C+G++ ++K + A V+ NF L Sbjct: 445 VPFSAGPRNCIGQKFGVLEIKVLLAAVIRNFKL 477
>Q9V4T3:C4AD1_DROME Probable cytochrome P450 4ad1 - Drosophila melanogaster (Fruit fly)| Length = 516 Score = 91.3 bits (225), Expect = 1e-17 Identities = 111/502 (22%), Positives = 204/502 (40%), Gaps = 32/502 (6%) Frame = +3 Query: 153 PTEWPLLGHLLSTLANVSNLHDWATGVLATTR-YNFAAHMGLTGVRF-FLTCDPSNVRHI 326 PT +P +G+L + ++ VL R Y+F L +++ + DP+ +++I Sbjct: 38 PTPYPFVGNLFQFGLKPA---EYPKKVLQYCRKYDFQGFRSLVFLQYHMMLSDPAEIQNI 94 Query: 327 FISNSINYPRGEEYADIFDVLGDGIFNADGESWRRQRAKSQLIMASPRFRSFSARCTRDK 506 S+S+ Y + Y+ + LGDG+ + G W + + + +P F + Sbjct: 95 LSSSSLLY-KEHLYSFLRPWLGDGLLTSSGARWLKHQK-----LYAPAFERSAIEGYLRV 148 Query: 507 VERSLLPFLAHA---ADVGARCDLHDVLLRLMFDMTCNLVFGVDPGCLQIGLPSL--PLA 671 V R+ F+ +D D +++ + D+ C G D L L + Sbjct: 149 VHRTGGQFVQKLDVLSDTQEVFDAQELVAKCTLDIVCENATGQDSSSLNGETSDLHGAIK 208 Query: 672 RAMDDVLETLFLRHVIPPACWRLMYRYGFGPEKKMAVARRIIDRFAADTIVKRRYSGHKL 851 D V E F A +RL Y + +++ R ++R I +RR H+L Sbjct: 209 DLCDVVQERTFSIVKRFDALFRLTSYY-MKQRRALSLLRSELNRI----ISQRR---HQL 260 Query: 852 RGEGITESSDILS------FFICNDDASEHSDEFLRDTAVNLLFAGRDTTGAVLSWFFYL 1013 E + ++ D + + + +F G D A +S+ Y Sbjct: 261 AAENTCQQGQPINKPFLDVLLTAKLDGKVLKEREIIEEVSTFIFTGHDPIAAAISFTLYT 320 Query: 1014 LCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHK 1193 L + ++Q +E I + D + L M YL + E LRLYPSVP+ + Sbjct: 321 LSRHSEIQQKAAEEQRRIFGENFAGEA---DLARLDQMHYLELIIRETLRLYPSVPLIAR 377 Query: 1194 AATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYK 1373 N + +G ++ +++ +MG E + C F PER+ G + + +K Sbjct: 378 T-NRNPIDINGTKVAKCTTVIMCLIAMGYNEKYFDDPCT-FRPERFENPTGNVGIEA-FK 434 Query: 1374 FIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTL-----------------ETVPGHTVK 1502 + F+AGPR C+ ++ A QMK + + +L F + + VP Sbjct: 435 SVPFSAGPRRCIAEKFAMYQMKALLSQLLRRFEILPAVDGLPPGINDHSREDCVPQSEYD 494 Query: 1503 PKLSI--VLHMKNGLAVTVKRR 1562 P L+I L +NG+ + +++R Sbjct: 495 PVLNIRVTLKSENGIQIRLRKR 516
>Q9VGZ0:C12E1_DROME Probable cytochrome P450 12e1, mitochondrial precursor - Drosophila| melanogaster (Fruit fly) Length = 514 Score = 91.3 bits (225), Expect = 1e-17 Identities = 107/430 (24%), Positives = 176/430 (40%), Gaps = 29/430 (6%) Frame = +3 Query: 273 LTGVRFFLTCDPSNVRHIFISNSINYP--RGEEYADIFDVLG--------DGIFNADGES 422 + G LT +P + IF N YP R E D F + DG+ + +G + Sbjct: 76 VAGTDLVLTMNPQDYEVIF-RNEGQYPYRRSFEVMDYFKRVHRREVFDGYDGLTSGNGPA 134 Query: 423 WRRQRAKSQLIMASPR----FRSFSARCTRDKVERSLL---PFLAHAADVGARCDLHDVL 581 W + R I+ PR + + + + + +ER + P D D + Sbjct: 135 WGKMRTAVNPILLQPRNAKLYMTNLVQVSDEFLERIRIIRDPVTQEMPD-----DFAVDI 189 Query: 582 LRLMFDMTCNLVFGVDPGCL---QIGLPSLPLARAMDDVLETLFLRHVIPPACWRLMYRY 752 L+ + C++ G L + L A+ DV+E F ++P A W+ + Sbjct: 190 RHLVIESICSVALNTHLGLLGEQRNNKDIQKLVLALQDVVELGFQLDIMP-AFWKYLPMP 248 Query: 753 GFGPEKKMAVARRIIDRFAADTIVKRRYSGHKLRGEGITESSDILSFFICNDDASEHSDE 932 F KK+ + I F I G+ L+ + L+ E Sbjct: 249 NF---KKLMRSLDTITDFCYFHI------GNALKRIEEDAKAGTLNEIGLETSLLEKLAR 299 Query: 933 FLRDTAV----NLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVV 1100 F R TAV +LLFAG D T L + L ++P + +L+E+ I K Sbjct: 300 FDRQTAVIIAMDLLFAGADPTLVTLGGILFSLSKSPDKQARLLEEIRGILPNKDSS---- 355 Query: 1101 LDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKI-LVYSYSMG 1277 L + ++ YL A + E +R+YP P T + H DV+ SG+ + AG + + +Y M Sbjct: 356 LTIENMRNLPYLRACIKEGIRMYPIGPGTLRRMPH-DVVLSGYRVVAGTDVGIAANYQMA 414 Query: 1278 RMEGVWGKDCMEFSPERWITDDGKL----RHQPPYKFIAFNAGPRTCLGKEVAFTQMKTV 1445 ME K EF PERW+ D+ P+ ++ F GPR+C GK + ++ Sbjct: 415 NMEQFVPK-VREFIPERWLRDESNSHLVGETATPFMYLPFGFGPRSCAGKRIVDMMLEIA 473 Query: 1446 AATVLWNFTL 1475 + ++ NF + Sbjct: 474 ISRLVRNFKI 483
>Q02928:CP4AB_HUMAN Cytochrome P450 4A11 precursor - Homo sapiens (Human)| Length = 519 Score = 90.9 bits (224), Expect = 2e-17 Identities = 61/218 (27%), Positives = 99/218 (45%) Frame = +3 Query: 906 DDASEHSDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKV 1085 ++ S SD+ LR +F G DTT + +SW Y L +P+ ++ +E+ + + Sbjct: 301 ENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSL-----L 355 Query: 1086 DDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYS 1265 D + + L M Y + E LRLYP VP + + P G + G +L+ Sbjct: 356 GDGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLSI 415 Query: 1266 YSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTV 1445 Y + VW + F P R+ G +H + F+ F+ G R C+GK+ A ++K Sbjct: 416 YGLHHNPKVWPNPEV-FDPFRFAP--GSAQHS--HAFLPFSGGSRNCIGKQFAMNELKVA 470 Query: 1446 AATVLWNFTLETVPGHTVKPKLSIVLHMKNGLAVTVKR 1559 A L F L P P +VL KNG+ + ++R Sbjct: 471 TALTLLRFELLPDPTRIPIPIARLVLKSKNGIHLRLRR 508
>Q2XV99:CP11A_MACFA Cytochrome P450 11A1, mitochondrial precursor - Macaca fascicularis| (Crab eating macaque) (Cynomolgus monkey) Length = 521 Score = 90.9 bits (224), Expect = 2e-17 Identities = 102/395 (25%), Positives = 176/395 (44%), Gaps = 10/395 (2%) Frame = +3 Query: 396 GIFNADGESWRRQR-AKSQLIMASPRFRSFSARCTRDKVERSLLPFLAH----AADVGAR 560 G+ +W++ R A +Q +MA ++F D V R + L A Sbjct: 138 GVLLKKSAAWKKDRVALNQEVMAPETTKNFLPLL--DAVSRDFVSVLHRRIKKAGSGNFS 195 Query: 561 CDLHDVLLRLMFDMTCNLVFGVDPGCLQIGLPSLPLARAMDDVLETLFLRHV----IPPA 728 D+ D L R F+ N++FG G L+ + P + D + +F V +PP Sbjct: 196 GDISDDLFRFAFESITNVIFGERQGMLEEVVN--PEGQRFIDAIYQMFHTSVHMLNLPPD 253 Query: 729 CWRLMYRYGFGPEKKMAVARRIIDRFAADTIVKRRYSGHKLRGEGITESSDILSFFICND 908 +RL + K VA R + AD + + + +G + IL + + D Sbjct: 254 LFRLFRTKTW----KDHVAPRDVIFSKADMYTENFHWELRQKGNVHHDYRGIL-YRLLGD 308 Query: 909 DASEHSDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVD 1088 S+ S E ++ +L G DTT L W Y + N +V+ M+ E+ +AAR++ Sbjct: 309 --SKMSFEDIKANVTEMLAGGVDTTSMTLQWHLYEMARNLKVQDMLRAEV--LAARRQAQ 364 Query: 1089 -DMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYS 1265 DM A+ L + L A++ E LRL+P + +T + ND++ G+ I A + V Sbjct: 365 GDM----ATILQLVPLLKASIKETLRLHP-ISVTLQRYLVNDLVLRGYMIPAKTLVQVAI 419 Query: 1266 YSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTV 1445 Y++GR E + D F P RW++ D + + ++ + F G R CLG+ +A +M Sbjct: 420 YALGR-EPTFFFDPENFDPTRWLSKDKNITY---FRNLGFGWGVRQCLGRRIAELEMTIF 475 Query: 1446 AATVLWNFTLETVPGHTVKPKLSIVLHMKNGLAVT 1550 +L NF +E V +++L + ++ T Sbjct: 476 LINMLENFRVEIQHLSDVGTTFNLILMPEKPISFT 510
>O70537:CP3AV_MESAU Cytochrome P450 3A31 - Mesocricetus auratus (Golden hamster)| Length = 501 Score = 90.5 bits (223), Expect = 2e-17 Identities = 110/477 (23%), Positives = 189/477 (39%), Gaps = 16/477 (3%) Frame = +3 Query: 132 KKTTKEEPTEWPLLGHLLSTLANVSNLHDWATGVLATTRYNFAAHMGLTGVRFFLTCDPS 311 KK P P LG++L+ + W + +Y + F D Sbjct: 34 KKQGIPGPKPLPFLGNVLNYYKGI-----WTFDIECHKKYGKIWGLFEGQRPLFTVTDTE 88 Query: 312 NVRHIFISNSINYPRGEEYADIFDVLGDGIFNADGESWRRQRAKSQLIMASPRFRSFSAR 491 ++++ + + ++ + + E W+R RA + SP F S + Sbjct: 89 MIKNVLVKECYSIFTNRRDFGPVGIMSKAVSISKDEEWKRIRA-----LLSPTFTSGKLK 143 Query: 492 CTRDKVERS---LLPFLAHAADVGARCDLHDVLLRLMFDMTCNLVFGVDPGCLQIGLPSL 662 +E+ L+ FL A+ G +V D+ + FGV L L Sbjct: 144 EMFPIIEQYGDILVKFLRREAEKGNPVTTKEVFGAYSMDVITSTAFGVSVDSLNNPKDLL 203 Query: 663 PLARAM--DDVLETLFLRHVIPPACWRLMYRYGFG--PEKKMAVARRIIDRFAADTIVKR 830 R + D + LFL V+ P + + P+ ++ R+ +D+ + + Sbjct: 204 WKGRKLLRFDFFDPLFLSVVLFPFLIPIYEKLNVSMFPKDSISFFRKFVDKTKENRLDYN 263 Query: 831 RYSGHKLRGEGITESSDILSFFICNDDASEHSDEFLRDT-----AVNLLFAGRDTTGAVL 995 + H++ D L + + D S+ S + L D ++ +FAG DTT + L Sbjct: 264 QK--HRV---------DFLQLMMNSHDNSKDSHKALSDMEIIAQSIIFIFAGYDTTSSTL 312 Query: 996 SWFFYLLCENPRVEQMILDEL---APIAARKKVDDMVVLDASELSSMVYLHAALCECLRL 1166 S+ YLL +P V++ + +E+ P AR D ++ M YL L E LRL Sbjct: 313 SFALYLLATHPDVQKKLQEEIDIALPNKARPSYDKVM--------EMEYLDMVLNETLRL 364 Query: 1167 YPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWITDD- 1343 YP + + DV G + G ++V +++ W + +F PER+ ++ Sbjct: 365 YP-IGSRLERVCKQDVEMDGVFVPKGSIVMVPVFALHYDPQYWPEP-EKFRPERFSKENK 422 Query: 1344 GKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLETVPGHTVKPKLS 1514 G + PY F+ F GPR C+G A MK VL NF+L+ + KLS Sbjct: 423 GSI---DPYIFLPFGNGPRNCIGMRFALMNMKLALTKVLQNFSLQPCKETQIPMKLS 476
>Q43068:C82A1_PEA Cytochrome P450 82A1 - Pisum sativum (Garden pea)| Length = 544 Score = 90.1 bits (222), Expect = 3e-17 Identities = 53/185 (28%), Positives = 94/185 (50%), Gaps = 2/185 (1%) Frame = +3 Query: 927 DEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLD 1106 D ++ T + L+ G DTT L+W LL ++P V + + +EL +++ ++ Sbjct: 327 DTIIKATTLELILGGSDTTAGTLTWAMCLLLKHPHVLEKLKEELNTYIGKERC-----VN 381 Query: 1107 ASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRME 1286 S+++ +VYLHA + E LRLYP P + D G+ IK G +++ + + R Sbjct: 382 ESDINKLVYLHAIIKETLRLYPPAPFSSPREFTEDCTIGGYHIKKGTRLMPNLWKIHRDP 441 Query: 1287 GVWGKDCMEFSPERWIT--DDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVL 1460 VW D +EF PER+++ D +R Q ++ + F +G R C G + + + A L Sbjct: 442 SVW-PDPLEFKPERFLSTHKDVDVRGQ-NFELLPFGSGRRMCAGMSLGLHMVHYILANFL 499 Query: 1461 WNFTL 1475 +F + Sbjct: 500 HSFEI 504
>Q9NGX9:CP302_DROME Cytochrome P450 302a1, mitochondrial precursor - Drosophila| melanogaster (Fruit fly) Length = 489 Score = 89.7 bits (221), Expect = 4e-17 Identities = 92/365 (25%), Positives = 164/365 (44%), Gaps = 5/365 (1%) Frame = +3 Query: 396 GIFNADGESWRRQRAKSQLIMASPR-FRSFSARCTRDKVERSLLPFLAHAADVGARCDLH 572 G+ +G W R RA+ Q +++P+ R+F + D V + + FL + + GA D+ Sbjct: 118 GLLPTNGPEWWRIRAQVQKELSAPKSVRNFVRQV--DGVTKEFIRFLQESRNGGA-IDML 174 Query: 573 DVLLRLMFDMTCNLVFG--VDPGCLQIGLPSLPLARAMD--DVLETLFLRHVIPPACWRL 740 L RL ++TC L FG + Q P R MD + + L WR Sbjct: 175 PKLTRLNLELTCLLTFGARLQSFTAQEQDPRSRSTRLMDAAETTNSCILPTDQGLQLWRF 234 Query: 741 MYRYGFGPEKKMAVARRIIDRFAADTIVKRRYSGHKLRGEGITESSDILSFFICNDDASE 920 + F +K++ A+ ++ A + + + +G + S ++S ++ N + + Sbjct: 235 LETPSF---RKLSQAQSYMESVALELVEENVRNG--------SVGSSLISAYVKNPEL-D 282 Query: 921 HSDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVV 1100 SD + TA +LL AG DTT ++ Y + NP V+Q + +E + K D + Sbjct: 283 RSD--VVGTAADLLLAGIDTTSYASAFLLYHIARNPEVQQKLHEEARRVLPSAK--DELS 338 Query: 1101 LDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGR 1280 +DA + + Y A L E LRL P + + + D + SG+ + G ++ + R Sbjct: 339 MDALR-TDITYTRAVLKESLRLNP-IAVGVGRILNQDAIFSGYFVPKGTTVVTQNMVACR 396 Query: 1281 MEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVL 1460 +E + +D + F P+RW+ L PY + F G R C+ + +A M + +L Sbjct: 397 LEQHF-QDPLRFQPDRWLQHRSALN---PYLVLPFGHGMRACIARRLAEQNMHILLLRLL 452 Query: 1461 WNFTL 1475 + L Sbjct: 453 REYEL 457
>Q64441:CP24A_MOUSE Cytochrome P450 24A1, mitochondrial precursor - Mus musculus (Mouse)| Length = 514 Score = 89.4 bits (220), Expect = 5e-17 Identities = 112/471 (23%), Positives = 187/471 (39%), Gaps = 16/471 (3%) Frame = +3 Query: 138 TTKEEPTEWPLLGHLLSTL--ANVSNLHDWATGVLATTRYNFAAHMGLTGVRFFLTCDPS 311 T+ PT WPLLG LL + HD T +Y M L PS Sbjct: 56 TSLPGPTNWPLLGSLLEIFWKGGLKKQHD--TLAEYHKKYGQIFRMKLGSFDSVHLGSPS 113 Query: 312 NVRHIFISNSINYPRGE-----EYADIFDVLGDGIFNADGESWRRQRAKSQLIMASPRFR 476 + ++ + S + R E Y D + G+ +G+ W+R R+ Q + P Sbjct: 114 LLEALYRTESAHPQRLEIKPWKAYRDHRNE-AYGLMILEGQEWQRVRSAFQKKLMKP--- 169 Query: 477 SFSARCTRDKVERSLLPFLAHAADV----GARCDLHDVLLRLMFDMTCNLVFGVDPGCLQ 644 K+ L F+ ++ G DL+ L + F+ C +++ G LQ Sbjct: 170 -VEIMKLDKKINEVLADFMGQIDELRDERGRIQDLYSELNKWSFESICLVLYEKRFGLLQ 228 Query: 645 IGLP--SLPLARAMDDVLETLFLRHVIPPACWRLMYRYGFGPEKKMAVARRIIDRFAADT 818 +L A+ ++ T V P + + K+ A + A DT Sbjct: 229 KDTEEEALTFIAAIKTMMSTFGKMMVTPVELHKRL-------NTKVWQAHTL----AWDT 277 Query: 819 IVK--RRYSGHKLRGEGITESSDILSFFICNDDASEH-SDEFLRDTAVNLLFAGRDTTGA 989 I K + H+L +D F+C+ +H S + L L A +TT Sbjct: 278 IFKSVKPCIDHRLERYSQQPGAD----FLCDIYQQDHLSKKELYAAVTELQLAAVETTAN 333 Query: 990 VLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAALCECLRLY 1169 L W Y L NP+V+Q +L E+ + + D A ++ +M YL A L E +RL Sbjct: 334 SLMWILYNLSRNPQVQQRLLREIQSV-----LPDNQTPRAEDVRNMPYLKACLKESMRLT 388 Query: 1170 PSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWITDDGK 1349 PSVP T + VL + + G + + + +G E + +D +F PERW+ + K Sbjct: 389 PSVPFTTRTLDKPTVL-GEYTLPKGTVLTLNTQVLGSSEDNF-EDADKFRPERWLEKEKK 446 Query: 1350 LRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLETVPGHTVK 1502 + P+ + F G R C+G+ +A Q+ ++ + + V+ Sbjct: 447 IN---PFAHLPFGVGKRMCIGRRLAELQLHLALCWIIQKYNIVATDSEPVE 494
>P30611:CP52N_CANTR Cytochrome P450 52B1 - Candida tropicalis (Yeast)| Length = 506 Score = 89.0 bits (219), Expect = 6e-17 Identities = 104/447 (23%), Positives = 178/447 (39%), Gaps = 21/447 (4%) Frame = +3 Query: 279 GVRFFLTCDPSNVRHIF---ISNSINYPRGEEYADIFDVLGDGIFNADGESWRRQRAKSQ 449 G +T DP N++ + + + +Y G + + LG GIF +GE+W+ R+ Sbjct: 98 GNELIMTKDPENIKVLLRFPVFDKFDY--GTRSSAVQPSLGMGIFTLEGENWKATRSV-- 153 Query: 450 LIMASPRFRSFSARCTRDKVERSLLPFLAHAADVGARCDLHDV---LLRLMFDMTCNLVF 620 R+ R + DKV F + + D+ L+L +++ +F Sbjct: 154 -------LRNMFDRKSIDKVHDFEPHFKTLQKRIDGKVGYFDIQQEFLKLGLELSIEFIF 206 Query: 621 GVDPGCLQIGLPSLP----LARAMDDVLETLFLRHVIPPACWRLM-YRYGFGPEKKMAVA 785 G Q+ +P +A D + + LR ++ W +RY + A Sbjct: 207 G------QVVSEDVPHYDDFTQAWDRCQDYMMLRLLLGDFYWMANDWRYKQSNQIVQAFC 260 Query: 786 RRIIDRFAADTIVKRRYSGHKLRGEGITESSDILSFFICNDDASEHSDEFLRDTAVNLLF 965 ++ + +T + H+L ++ F+RD A++L+ Sbjct: 261 DYLVQKSLENTCNDKFVFVHQLAKHTTNKT-------------------FIRDQALSLIM 301 Query: 966 AGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAA 1145 A RDTT ++++ L + +E I A ++ +L L Y+ A Sbjct: 302 ASRDTTAELMAFTILELSRKSHHLGKLREE---IDANFGLESPDLLTFDSLRKFKYVQAI 358 Query: 1146 LCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILV-YSYSMG------RMEGV--WG 1298 L E LR+YP VP K A LP G D ILV S+G ++ V +G Sbjct: 359 LNETLRMYPGVPRNMKTAKCTTTLPKGGGPDGQDPILVKKGQSVGFISIATHLDPVLNFG 418 Query: 1299 KDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNF-TL 1475 D F P+RW K K++ FNAGPRTCLG++ + + + + T+ Sbjct: 419 SDAHVFRPDRWFDSSMK---NLGCKYLPFNAGPRTCLGQQYTLIEASYLLVRLAQTYETV 475 Query: 1476 ETVPGHTVKPKLSIVLHMKNGLAVTVK 1556 E+ P P+ +++M V VK Sbjct: 476 ESHPDSVYPPRKKALINMCAADGVDVK 502
>O73853:CP17A_ICTPU Cytochrome P450 17A1 - Ictalurus punctatus (Channel catfish)| Length = 514 Score = 89.0 bits (219), Expect = 6e-17 Identities = 77/327 (23%), Positives = 149/327 (45%), Gaps = 11/327 (3%) Frame = +3 Query: 564 DLHDVLLRLMFDMTCNLVFGVDPGCLQIGLPSLP-LARAMDDVLETLFLRHVIPPACWRL 740 DL L R + ++ C L F + G P + + +++T+ ++ W Sbjct: 171 DLAPELTRAVTNVVCTLCFS---SSYKRGDPEFEAMLKYSQGIVDTVAKDSLVDIFPWLQ 227 Query: 741 MYRYGFGPEKKMAVARRIIDRFAADTIVKRRYSGHKLRGEGITESSDILSFFICNDDASE 920 ++ P + + + RR + D +++++Y HK + D+ + ++SE Sbjct: 228 LF-----PNEDLRILRRCVS--IRDKLLQKKYEEHKADFSDNIQR-DLFDALLRAKNSSE 279 Query: 921 HS----------DEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIA 1070 ++ D+ L T ++ AG +TT VL W L +P+V++ I +EL Sbjct: 280 NNNTSTQDVGLTDDHLLMTVGDIFGAGVETTTTVLKWSILYLIHHPQVQRKIQEELDAKI 339 Query: 1071 ARKKVDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDK 1250 R + + ++ ++ YL A + E LR+ P P+ +D + ++ G + Sbjct: 340 GRDRHPQV-----NDRGNLPYLEATIREVLRIRPVSPLLIPHVALSDANIGEYTVQKGTR 394 Query: 1251 ILVYSYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFT 1430 ++V +S+ E W K+ F+PER++ ++G P ++ F AG R CLG+ +A Sbjct: 395 VIVNLWSLHHDEKEW-KNPELFNPERFLNEEGNSLCCPSLSYLPFGAGVRVCLGEALAKL 453 Query: 1431 QMKTVAATVLWNFTLETVPGHTVKPKL 1511 ++ + +L FTLE VPG P+L Sbjct: 454 ELFLFLSWILQRFTLE-VPGGQPLPEL 479
>Q9VCW1:CP6D4_DROME Probable cytochrome P450 6d4 - Drosophila melanogaster (Fruit fly)| Length = 515 Score = 88.6 bits (218), Expect = 8e-17 Identities = 95/425 (22%), Positives = 181/425 (42%), Gaps = 20/425 (4%) Frame = +3 Query: 348 YPRGEEYADIFDVLGDGIFNADGESWRRQRAKSQLIMASPRFRSFSARCTRDKVERSLLP 527 + RG + D L IF+ G+SWR R S + +S + + D ++ + Sbjct: 100 HDRGVYVDEERDPLSANIFSLRGQSWRSMRHMLSPCFTSGKLKSMFST-SEDIGDKMVAH 158 Query: 528 FLAHAADVGAR-CDLHDVLLRLMFDMTCNLVFGVDPGCLQIG----LPSLPLARAMDDVL 692 + G + D+ V+ D+ + +FG+D + + LARA + Sbjct: 159 LQKELPEEGFKEVDIKKVMQNYAIDIIASTIFGLDVNSFENPDNKFRKLVSLARANNRFN 218 Query: 693 ETLFLRHVIPPACWRLMYRYGFGPEKKMAVARRIIDRFAADTIVKRRYSGH--------- 845 + + P+ + ++R GF +A+ + + +T+ R G Sbjct: 219 AMFGMMIFLVPSIAQFLFRIGFKNPVGLAMLQIV-----KETVEYREKHGIVRKDLLQLL 273 Query: 846 -KLRGEGITESSDILSFFIC---NDDASEHSDEFLRDTAVNLLFAGRDTTGAVLSWFFYL 1013 +LR G + +D SF I + S E + A AG++TTG+ ++ Y Sbjct: 274 IQLRNTGKIDENDEKSFSIQKTPDGHIKTISLEAITAQAFIFYIAGQETTGSTAAFTIYE 333 Query: 1014 LCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHK 1193 L + P + + + DE+ A+ D + D+ L+ M +L + E +R YP +PI ++ Sbjct: 334 LAQYPELLKRLQDEVDETLAKN--DGKITYDS--LNKMEFLDLCVQETIRKYPGLPILNR 389 Query: 1194 AATHNDVLP-SGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPY 1370 T + +P + H I G +++ Y + + + D + PER+ + R+ P Sbjct: 390 ECTQDYTVPDTNHVIPKGTPVVISLYGIHH-DAEYFPDPETYDPERFSEES---RNYNPT 445 Query: 1371 KFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLETVPGHTVKPKLS-IVLHMKNGLAV 1547 F+ F GPR C+ + + K +L NF +E + ++ + S I L K+G+ V Sbjct: 446 AFMPFGEGPRICIAQRMGRINSKLAIIKILQNFNVEVMSRSEIEFENSGIALIPKHGVRV 505 Query: 1548 TVKRR 1562 + +R Sbjct: 506 RLSKR 510
>O73686:CP192_CARAU Cytochrome P450 19 type 2 - Carassius auratus (Goldfish)| Length = 518 Score = 88.6 bits (218), Expect = 8e-17 Identities = 95/368 (25%), Positives = 159/368 (43%), Gaps = 1/368 (0%) Frame = +3 Query: 399 IFNADGESWRRQRAKSQLIMASPRFRSFSARCTRDKVERSLLPFLAHAADVGARCDLHDV 578 IFN++ W++ R+ + P + C + L L+H D + D+ ++ Sbjct: 153 IFNSNVALWKKVRSFYAKALTGPGLQRTLEICITST--NTHLDNLSHLMDARGQVDILNL 210 Query: 579 LLRLMFDMTCNLVFGVDPGCLQIGLPSLPLARAMDDVLETLFLRHVIPPACWRLMYRYGF 758 L ++ D++ L GV L L + + +T + P +RL + + Sbjct: 211 LRCIVVDISNRLFLGVP-------LNEHDLLQKIHKYFDTWQTVLIKPDVYFRLAW---W 260 Query: 759 GPEKKMAVARRIIDRFAADTIVKRRYSGHKLRGEGITESSDILSFFICNDDASEHSDEFL 938 K A+ + D AA KR +L + D + I E S E + Sbjct: 261 LHRKHKRDAQELQDAIAALIEQKRV----QLTRAEKFDQLDFTAELIFAQSHGELSTENV 316 Query: 939 RDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASEL 1118 R + ++ A DT L + LL +NP VE IL E+ + A + L S L Sbjct: 317 RQCVLEMIIAAPDTLSISLFFMLLLLKQNPDVELKILQEMNAVLAGRS------LQHSHL 370 Query: 1119 SSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWG 1298 S L + + E LR +P V T + A +DV+ G+++K G I++ ++GRM Sbjct: 371 SGFHILESFINESLRFHPVVDFTMRRALDDDVI-EGYKVKRGTNIIL---NVGRMHR--- 423 Query: 1299 KDCMEFSPE-RWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTL 1475 EF P+ + D ++ P F F +GPR+C+GK +A MK++ T+L F++ Sbjct: 424 ---SEFFPKPNEFSLDNFQKNVPSRFFQPFGSGPRSCVGKHMAMVMMKSILVTLLSRFSV 480 Query: 1476 ETVPGHTV 1499 V G TV Sbjct: 481 CPVKGCTV 488
>Q9STK7:C71AQ_ARATH Cytochrome P450 71A26 - Arabidopsis thaliana (Mouse-ear cress)| Length = 489 Score = 88.6 bits (218), Expect = 8e-17 Identities = 87/378 (23%), Positives = 163/378 (43%), Gaps = 7/378 (1%) Frame = +3 Query: 414 GESWRRQRAKSQLIMASPRF-RSFSARCTRDKVERSLLPFLAHAADVGARCDLHDVLLRL 590 GE WR+ ++ L + S + RSF R R++ ++ + + + +L +L+ L Sbjct: 120 GEYWRQMKSVCVLHLFSNKMVRSF--REVREEEISLMMEKIRKS--ISLPVNLSKILVSL 175 Query: 591 MFDMTCNLVFGVDPGCLQIGLPSLPLARAMDDVLETLFLRHVIPPACWRLMYRYGFGPEK 770 D+ C + G G L ++ +L T + +P W R G + Sbjct: 176 TNDVICKVALGRKYGG---ETDFKELMERLNKLLGTFSVGSYVPWLAWIDWIR---GLDC 229 Query: 771 KMAVARRIIDRFAADTIVKRRYSGHKLRGEGITESSDILSFFICNDDAS-EHSDEFLRDT 947 ++ +D+F + +V+ G++ +T+ D+L + E + ++ Sbjct: 230 QLEKTANDVDKFF-ERVVQDHVDGNR----DMTDFVDVLLAIQRDKTVGFEINRVSIKAI 284 Query: 948 AVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSM 1127 +N+ G DT+ ++ W L +P+ + + +E+ I K + E+ +M Sbjct: 285 VMNVFVGGTDTSSTLMEWAMTELLRHPKCLKRLQEEVRTICKDKSS-----VSEEEIQNM 339 Query: 1128 VYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDC 1307 YL A + E LRL+P +P+ + DV H I AG ++L+ ++++GR WG D Sbjct: 340 SYLKAVIKEALRLHPPLPLMVPHESTQDVRLGDHHIPAGTQVLINAWAIGREAATWGPDV 399 Query: 1308 MEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVL----WNFTL 1475 EF PER + R Q ++ I F +G R C A + V A ++ W ++ Sbjct: 400 EEFRPERHLDSSVDYRGQ-AFELIPFGSGRRICPAISFAVVLNEVVLANLVHRFDWRLSV 458 Query: 1476 ETVPGHT-VKPKLSIVLH 1526 E+ T V I +H Sbjct: 459 ESTEDQTEVAESTGIAIH 476
>Q9SBQ9:F3PH_PETHY Flavonoid 3'-monooxygenase - Petunia hybrida (Petunia)| Length = 512 Score = 88.2 bits (217), Expect = 1e-16 Identities = 70/284 (24%), Positives = 124/284 (43%), Gaps = 9/284 (3%) Frame = +3 Query: 759 GPEKKMAVARRIIDRFAADTIVKRRYSGHKLRGEGITESSDILSFFIC--NDDASEH--- 923 G KM D F D + + + G+ E D+LS I NDDA Sbjct: 236 GVAAKMKKLHARFDAFLTDILEEHK-------GKIFGEMKDLLSTLISLKNDDADNDGGK 288 Query: 924 -SDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVV 1100 +D ++ +NL AG DT+ + + W L NP++ E+ + R + + Sbjct: 289 LTDTEIKALLLNLFVAGTDTSSSTVEWAIAELIRNPKILAQAQQEIDKVVGRDR-----L 343 Query: 1101 LDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGR 1280 + +L+ + YL A + E RL+PS P++ +G+ I G +L+ +++ R Sbjct: 344 VGELDLAQLTYLEAIVKETFRLHPSTPLSLPRIASESCEINGYFIPKGSTLLLNVWAIAR 403 Query: 1281 MEGVWGKDCMEFSPERWITDDGKLR---HQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAA 1451 W D +EF PER++ K + ++ I F AG R C G + ++ + A Sbjct: 404 DPNAWA-DPLEFRPERFLPGGEKPKVDVRGNDFEVIPFGAGRRICAGMNLGIRMVQLMIA 462 Query: 1452 TVLWNFTLETVPGHTVKPKLSIVLHMKNGLAVTVKRRNFFTAKP 1583 T++ F + V G +L +L+M+ +T++R + P Sbjct: 463 TLIHAFNWDLVSG-----QLPEMLNMEEAYGLTLQRADPLVVHP 501
>P70085:CP17A_ORYLA Cytochrome P450 17A1 - Oryzias latipes (Medaka fish) (Japanese| ricefish) Length = 517 Score = 88.2 bits (217), Expect = 1e-16 Identities = 83/356 (23%), Positives = 156/356 (43%), Gaps = 19/356 (5%) Frame = +3 Query: 513 RSLLPFLAHAADVGARCDLHDVLLRLMFDMTCNLVFGVDPGCLQIGLPSLP-LARAMDDV 689 +SL L+ AA G DL L R + ++ C+L F G P + R + Sbjct: 156 QSLCSTLSEAAATGLALDLSPELTRAVTNVICSLCFN---SSYSRGDPEFEAMLRYSQGI 212 Query: 690 LETLFLRHVIPPACWRLMYRYGFGPEKKMAVARRIIDRFAADTIVKRRYSGHK------- 848 ++T+ ++ W ++ P K + + ++ + D ++++++ HK Sbjct: 213 VDTVAKDSLVDIFPWLQIF-----PNKDLRLLKQCVA--VRDQLLQKKFEEHKSDYSDHV 265 Query: 849 --------LRGEGITESSDILSFFICNDDASEHSDEFLRDTAVNLLFAGRDTTGAVLSWF 1004 LR + E+++ + F + +A SD+ L T ++ AG +TT VL W Sbjct: 266 QRDLLDALLRAKRSAENNNTAAEF--SAEAVGLSDDHLLMTVGDIFGAGVETTTTVLKWA 323 Query: 1005 FYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAALCECLRLYPSVPI 1184 L P V++ I +EL +KV S+ S+ +L A + E LR+ P P+ Sbjct: 324 ITYLIHYPEVQKQIQEELD-----RKVGVDRPPQLSDRGSLPFLEATIREVLRIRPVAPL 378 Query: 1185 THKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQP 1364 +D ++ G ++++ +S+ E W + F+P R+++ DG P Sbjct: 379 LIPHVALSDTSLGDFTVRKGTRVVINLWSLHHDEKEWTNPDL-FNPGRFLSADGSSLTLP 437 Query: 1365 PYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLETVPGH---TVKPKLSIVL 1523 ++ F AG R CLG+ +A ++ + +L FTL P +++ K +VL Sbjct: 438 SSSYLPFGAGLRVCLGEALAKMELFLFLSWILQRFTLSVPPSQSLPSLEGKFGVVL 493
>P05108:CP11A_HUMAN Cytochrome P450 11A1, mitochondrial precursor - Homo sapiens (Human)| Length = 521 Score = 88.2 bits (217), Expect = 1e-16 Identities = 102/395 (25%), Positives = 174/395 (44%), Gaps = 10/395 (2%) Frame = +3 Query: 396 GIFNADGESWRRQR-AKSQLIMASPRFRSFSARCTRDKVERSLLPFLAH----AADVGAR 560 G+ +W++ R A +Q +MA ++F D V R + L A Sbjct: 138 GVLLKKSAAWKKDRVALNQEVMAPEATKNFLPLL--DAVSRDFVSVLHRRIKKAGSGNYS 195 Query: 561 CDLHDVLLRLMFDMTCNLVFGVDPGCLQIGLPSLPLARAMDDVLETLFLRHV----IPPA 728 D+ D L R F+ N++FG G L+ + P A+ D + +F V +PP Sbjct: 196 GDISDDLFRFAFESITNVIFGERQGMLEEVVN--PEAQRFIDAIYQMFHTSVPMLNLPPD 253 Query: 729 CWRLMYRYGFGPEKKMAVARRIIDRFAADTIVKRRYSGHKLRGEGITESSDILSFFICND 908 +RL + K VA + AD + Y + +G + IL + + D Sbjct: 254 LFRLFRTKTW----KDHVAAWDVIFSKADIYTQNFYWELRQKGSVHHDYRGIL-YRLLGD 308 Query: 909 DASEHSDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVD 1088 S+ S E ++ +L G DTT L W Y + N +V+ M+ E+ +AAR + Sbjct: 309 --SKMSFEDIKANVTEMLAGGVDTTSMTLQWHLYEMARNLKVQDMLRAEV--LAARHQAQ 364 Query: 1089 -DMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYS 1265 DM A+ L + L A++ E LRL+P + +T + ND++ + I A + V Sbjct: 365 GDM----ATMLQLVPLLKASIKETLRLHP-ISVTLQRYLVNDLVLRDYMIPAKTLVQVAI 419 Query: 1266 YSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTV 1445 Y++GR E + D F P RW++ D + + ++ + F G R CLG+ +A +M Sbjct: 420 YALGR-EPTFFFDPENFDPTRWLSKDKNITY---FRNLGFGWGVRQCLGRRIAELEMTIF 475 Query: 1446 AATVLWNFTLETVPGHTVKPKLSIVLHMKNGLAVT 1550 +L NF +E V +++L + ++ T Sbjct: 476 LINMLENFRVEIQHLSDVGTTFNLILMPEKPISFT 510
>O49342:C71AD_ARATH Cytochrome P450 71A13 - Arabidopsis thaliana (Mouse-ear cress)| Length = 497 Score = 88.2 bits (217), Expect = 1e-16 Identities = 83/379 (21%), Positives = 156/379 (41%), Gaps = 4/379 (1%) Frame = +3 Query: 345 NYPRGEEYADIFDVLGDGIFNADGESWRRQRAKSQLIMASPRFRSFSARCTRDKVERSLL 524 N PR + + + D +F GE WR+ ++ L + + + + D+V +++ Sbjct: 99 NRPRSKAVHGLMNGGRDVVFAPYGEYWRQMKSVCILNLLTNKMVESFEKVREDEVN-AMI 157 Query: 525 PFLAHAADVGARCDLHDVLLRLMFDMTCNLVFGVDPGCLQIGLPSLPLARAMDDVLETLF 704 L A+ + +L ++ + L D+T + G + R + ++L Sbjct: 158 EKLEKASSSSSSENLSELFITLPSDVTSRVALGRKHSEDETARDLKKRVRQIMELLGEFP 217 Query: 705 LRHVIPPACWRLMYRYGFGPEKKMAVARRIIDRFAADTIVKRRYSGHKLRGEGITESSDI 884 + +P W R GF + K V+R D D +V+ E + +D Sbjct: 218 IGEYVPILAWIDGIR-GFNNKIK-EVSRGFSDLM--DKVVQEHL-------EASNDKADF 266 Query: 885 LSFFICNDDASEHSDEFLRDTA----VNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILD 1052 + + + + R+ +++ G TT +L W L +P+ + + D Sbjct: 267 VDILLSIEKDKNSGFQVQRNDIKFMILDMFIGGTSTTSTLLEWTMTELIRSPKSMKKLQD 326 Query: 1053 ELAPIAARKKVDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHE 1232 E+ + E+ +M YL A + E LRL+PS+P+ DV G+ Sbjct: 327 EIRSTIRPHGS----YIKEKEVENMKYLKAVIKEVLRLHPSLPMILPRLLSEDVKVKGYN 382 Query: 1233 IKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLG 1412 I AG ++++ ++++ R +WG D EF PER + D G H +I F +G R C G Sbjct: 383 IAAGTEVIINAWAIQRDTAIWGPDAEEFKPERHL-DSGLDYHGKNLNYIPFGSGRRICPG 441 Query: 1413 KEVAFTQMKTVAATVLWNF 1469 +A + A ++ F Sbjct: 442 INLALGLAEVTVANLVGRF 460
>Q9VMS9:C4AC1_DROME Probable cytochrome P450 4ac1 - Drosophila melanogaster (Fruit fly)| Length = 509 Score = 87.8 bits (216), Expect = 1e-16 Identities = 93/428 (21%), Positives = 180/428 (42%), Gaps = 9/428 (2%) Frame = +3 Query: 306 PSNVRHIFISNSINYPRGEEYADIFDVLGDGIFNADGESWRRQRAKSQLIMASPRFRSFS 485 P +F S + + Y I LGDG+ + W +R +P F Sbjct: 101 PEEAEEVFQSTKL-ITKNVVYELIRPFLGDGLLISTDHKWHSRRKA-----LTPAFHFNV 154 Query: 486 ARCTRDKVERSLLPFL-AHAADVGARCDLHDVLLRLMFDMTCNLVFGVDPGCLQIGLPSL 662 + + FL ++ A +L+ V+ + C GV + G Sbjct: 155 LQSFLGIFKEECKKFLNVLEKNLDAELELNQVIPPFTLNNICETALGVKLDDMSEGNEYR 214 Query: 663 PLARAMDDVLETLFLRHVIPPACWRLMYRYGFGPEKKMAVARRIIDRFAADTIVKRRYS- 839 A+++VL ++ V P + Y + +G +K RI+ F++ I ++R Sbjct: 215 KAIHAIEEVL----IQRVCNPLMYYNWYFFVYGDYRKHLQNLRIVHDFSSRIIERKRQQF 270 Query: 840 GHKLRGE----GITESSDILSFFICNDDASEHSDEFLRDTAVNLLFAGRDTTGAVLSWFF 1007 K GE G + +L + + + + + D +F G DTT L + Sbjct: 271 QQKQLGEVDEFGRKQRYAMLDTLLAAEADGQIDHQGICDEVNTFMFEGYDTTSTCLIFTL 330 Query: 1008 YLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAALCECLRLYPSVPIT 1187 +L + V++ +E+ + +D + + + +VYL + E LR++PSVP Sbjct: 331 LMLALHEDVQKKCYEEVENLP-----EDSDDISMFQFNKLVYLECVIKESLRMFPSVPFI 385 Query: 1188 HKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPP 1367 + V+ +G + +I ++ Y + R + K + F P+R++ ++ RH P Sbjct: 386 GRQCVEETVV-NGMVMPKDTQISIHIYDIMRDPRHFPKPDL-FQPDRFLPENTVNRH--P 441 Query: 1368 YKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLETVPGHTVKP---KLSIVLHMKNG 1538 + ++ F+AG R C+G++ A +MK + A V+ NF L +P ++ + IVL + Sbjct: 442 FAYVPFSAGQRNCIGQKFAILEMKVLLAAVIRNFKL--LPATQLEDLTFENGIVLRTQEN 499 Query: 1539 LAVTVKRR 1562 + V + +R Sbjct: 500 IKVKLSKR 507
>Q27515:C13A6_CAEEL Putative cytochrome P450 CYP13A6 - Caenorhabditis elegans| Length = 518 Score = 87.8 bits (216), Expect = 1e-16 Identities = 95/400 (23%), Positives = 168/400 (42%), Gaps = 29/400 (7%) Frame = +3 Query: 399 IFNADGESWRRQRAKSQLIMASPRFRSFSARCTRDKVERSLLPFLAHAADVGARCDLHDV 578 IF+ G+ W+R R ++SP F + S R R+ V+ L + + + D+ Sbjct: 115 IFSTQGKRWKRLRT-----LSSPSFSNNSLRKVRNSVQECGTEILWNIEQKVRKNEDIDM 169 Query: 579 LLRLMFDMTCNLVFGVDPGCLQIGL---PSLPLARAMDDVLETLFLRHVIPPACWRLMYR 749 L+ + + T ++ + G + + P LP +A+ + +FL I P + + Sbjct: 170 LI-VYQEYTLGVISRIALGQSESNMFKNPLLPKVQAIFNGSWHVFLITGIFPPLAGVFRK 228 Query: 750 YGFGPEKKMAVARRIID--RFAADTIVKRRYSGHKLRGEGITESSDILSFFI-------- 899 A +I D A + +R + +++G E D + F+ Sbjct: 229 MSKMLPASFIPAFKIFDLIEVAVQARIDQR-AKDEIKGVEPGEPQDFIDLFLDARVPDVK 287 Query: 900 -----CNDDASEHS----------DEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRV 1034 N+D ++ S DE + V L AG DTT LS+ YLL +P + Sbjct: 288 ILSGEANEDFAKSSVVKINKELTFDEIIAQCFV-FLAAGFDTTALSLSYATYLLATHPEI 346 Query: 1035 EQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDV 1214 + + +E+ R+ D + D LS + YL + E LRLYP + + Sbjct: 347 QTKLQEEVD----RECPDPEIFFD--HLSKLKYLECVMKETLRLYPLGTTANTRKCMRET 400 Query: 1215 LPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWITDDGKLRH-QPPYKFIAFNA 1391 +G G I V ++++ +WG+D +F PERW ++G H + +I F + Sbjct: 401 TINGVNFDEGMNIQVDTWTLHHNPRIWGEDVEDFKPERW--ENGACEHLEHNGSYIPFGS 458 Query: 1392 GPRTCLGKEVAFTQMKTVAATVLWNFTLETVPGHTVKPKL 1511 GPR C+G +A + K + A +L ++ T + KL Sbjct: 459 GPRQCIGMRLAQMEQKILLAQILKEYSFRTTKNTQIPVKL 498
>O42145:C19AA_DANRE Cytochrome P450 19A1a - Danio rerio (Zebrafish) (Brachydanio rerio)| Length = 509 Score = 87.4 bits (215), Expect = 2e-16 Identities = 91/368 (24%), Positives = 154/368 (41%) Frame = +3 Query: 399 IFNADGESWRRQRAKSQLIMASPRFRSFSARCTRDKVERSLLPFLAHAADVGARCDLHDV 578 IFN++ W++ RA + P + CT S L L+ D + D+ ++ Sbjct: 153 IFNSNVALWKKVRAFYAKALTGPGLQRTMEICTTST--NSHLDDLSQLTDAQGQLDILNL 210 Query: 579 LLRLMFDMTCNLVFGVDPGCLQIGLPSLPLARAMDDVLETLFLRHVIPPACWRLMYRYGF 758 L ++ D++ L GV L L + + +T + P +RL + + Sbjct: 211 LRCIVVDVSNRLFLGVP-------LNEHDLLQKIHKYFDTWQTVLIKPDVYFRLDWLH-- 261 Query: 759 GPEKKMAVARRIIDRFAADTIVKRRYSGHKLRGEGITESSDILSFFICNDDASEHSDEFL 938 K A+ + D A K+ H + + + D + I E S E + Sbjct: 262 --RKHKRDAQELQDAITALIEQKKVQLAHAEKLDHL----DFTAELIFAQSHGELSAENV 315 Query: 939 RDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASEL 1118 R + ++ A DT L + LL +NP VE IL E+ + A + L S L Sbjct: 316 RQCVLEMVIAAPDTLSISLFFMLLLLKQNPDVELKILQEMDSVLAGQS------LQHSHL 369 Query: 1119 SSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWG 1298 S + L + + E LR +P V T + A +DV+ G+ +K G I++ M R E Sbjct: 370 SKLQILESFINESLRFHPVVDFTMRRALDDDVI-EGYNVKKGTNIILNVGRMHRSEF--- 425 Query: 1299 KDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLE 1478 FS + D ++ P F F +GPR+C+GK +A MK++ +L F++ Sbjct: 426 -----FSKPNQFSLDNFHKNVPSRFFQPFGSGPRSCVGKHIAMVMMKSILVALLSRFSVC 480 Query: 1479 TVPGHTVK 1502 + TV+ Sbjct: 481 PMKACTVE 488
>P37121:C76A1_SOLME Cytochrome P450 76A1 - Solanum melongena (Eggplant) (Aubergine)| Length = 467 Score = 87.0 bits (214), Expect = 2e-16 Identities = 70/269 (26%), Positives = 127/269 (47%), Gaps = 3/269 (1%) Frame = +3 Query: 765 EKKMAVARRIIDRFAADTIVKRRYSGHKLRGEGITESSDILSFFICN--DDASEHSDEFL 938 E+ M + I +F + I +R+ G K R I + D+L F + D+ + S++ + Sbjct: 205 ERDMGKGKEITKKFIEERIEERK-KGEKNRS--IKDLLDVLIDFEGSGKDEPDKLSEDEI 261 Query: 939 RDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMI-LDELAPIAARKKVDDMVVLDASE 1115 + + AG +TT + + W L +P+ + L+ L I KK ++ + Sbjct: 262 TVIILEMFLAGTETTSSSVEWALTELLRHPQAMAKVKLEILQVIGPNKKFEEC------D 315 Query: 1116 LSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVW 1295 + S+ Y+ A L E LRL+P +P+ D G++I G ++LV ++++GR W Sbjct: 316 IDSLPYMQAVLKEQLRLHPPLPLLIPRKAIQDTKFMGYDIPKGTQVLVNAWAIGRDPEYW 375 Query: 1296 GKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTL 1475 EF PER++ ++ Q Y+ I F AG R C+G + M ++L F Sbjct: 376 DNP-FEFKPERFLESKVDVKGQ-NYELIPFGAGRRMCVGLPLGHRMMHFTFGSLLHEFDW 433 Query: 1476 ETVPGHTVKPKLSIVLHMKNGLAVTVKRR 1562 E H V PK ++M+ + +T +++ Sbjct: 434 EL--PHNVSPK---SINMEESMGITARKK 457
>O35132:CP27B_RAT 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial precursor -| Rattus norvegicus (Rat) Length = 501 Score = 86.7 bits (213), Expect = 3e-16 Identities = 97/387 (25%), Positives = 163/387 (42%), Gaps = 11/387 (2%) Frame = +3 Query: 396 GIFNADGESWRRQRAKSQLIMASPRFRSFSARCTRDKVERSLLPFLAHAADVGARC---- 563 G+ ADGE W+R R+ ++ P+ + A T D V L+ L G+ Sbjct: 118 GLLTADGEEWQRLRSLLAPLLLRPQAAAGYAG-TLDSVVSDLVRRLRRQRGRGSGLPDLV 176 Query: 564 -DLHDVLLRLMFDMTCNLVFGVDPGCLQIGLPSLPLARAMDDVLETLFLRHVIPPACWRL 740 D+ + + ++ G GCL+ +P P + + ++F+ ++ A Sbjct: 177 LDVAGEFYKFGLEGIGAVLLGSRLGCLEAEVP--PDTETFIEAVGSVFVSTLLTMAMPSW 234 Query: 741 MYRYGFGPEKKMAVARRIIDRFA-ADTIVKRRYSGHKLRGEGITE----SSDILSFFICN 905 ++R GP ++ R FA A V++R +R +G E + L+ F+ Sbjct: 235 LHRLIPGPWARLC--RDWDQMFAFAQKHVEQREGEAAVRNQGKPEEDLPTGHHLTHFLFR 292 Query: 906 DDASEHSDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKV 1085 + S S + LL AG DT LSW Y L +P V+ + E I Sbjct: 293 EKVSVQS---IVGNVTELLLAGVDTVSNTLSWALYELSRHPEVQSALHSE---ITGAVNP 346 Query: 1086 DDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYS 1265 L A+ LS + L A + E LRLYP VP + D+ + I + + Sbjct: 347 GSYAHLQATALSQLPLLKAVIKEVLRLYPVVP-GNSRVPDRDICVGNYVIPQDTLVSLCH 405 Query: 1266 YSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTV 1445 Y+ R + ++ F+P RW+ +G H P+ + F G R+C+G+ +A +++ Sbjct: 406 YATSR-DPAQFREPNSFNPARWL-GEGPAPH--PFASLPFGFGKRSCIGRRLAELELQMA 461 Query: 1446 AATVLWNFTLETVPGH-TVKPKLSIVL 1523 A +L +F + PG VKP VL Sbjct: 462 LAQILTHFEVLPEPGALPVKPMTRTVL 488
>O15528:CP27B_HUMAN 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial precursor -| Homo sapiens (Human) Length = 508 Score = 85.9 bits (211), Expect = 5e-16 Identities = 98/392 (25%), Positives = 165/392 (42%), Gaps = 16/392 (4%) Frame = +3 Query: 396 GIFNADGESWRRQRAKSQLIMASPRFRSFSARCTRDKVERSLLPFLAHAADVGARC---- 563 G+ A+GE W+R R+ ++ P+ + A T + V L+ L G Sbjct: 125 GLLTAEGEEWQRLRSLLAPLLLRPQAAARYAG-TLNNVVCDLVRRLRRQRGRGTGPPALV 183 Query: 564 -DLHDVLLRLMFDMTCNLVFGVDPGCLQIGLP--SLPLARAMDDV-LETL-------FLR 710 D+ + + ++ G GCL+ +P + RA+ V + TL +LR Sbjct: 184 RDVAGEFYKFGLEGIAAVLLGSRLGCLEAQVPPDTETFIRAVGSVFVSTLLTMAMPHWLR 243 Query: 711 HVIPPACWRLMYRYGFGPEKKMAVARRIIDRFAADTIVKRRYSGHKLRGEGITESSDILS 890 H++P RL + ++ A A+R ++R A+ ++ K ES L+ Sbjct: 244 HLVPGPWGRLCRDW----DQMFAFAQRHVERREAEAAMRNGGQPEK-----DLESGAHLT 294 Query: 891 FFICNDDASEHSDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIA 1070 F+ ++ S + LL AG DT LSW Y L +P V+ + E I Sbjct: 295 HFLFREELPAQS---ILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSE---IT 348 Query: 1071 ARKKVDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDK 1250 A A+ LS + L A + E LRLYP VP + D+ + I Sbjct: 349 AALSPGSSAYPSATVLSQLPLLKAVVKEVLRLYPVVP-GNSRVPDKDIHVGDYIIPKNTL 407 Query: 1251 ILVYSYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFT 1430 + + Y+ R + + F P RW+ +G H P+ + F G R+C+G+ +A Sbjct: 408 VTLCHYATSR-DPAQFPEPNSFRPARWL-GEGPTPH--PFASLPFGFGKRSCMGRRLAEL 463 Query: 1431 QMKTVAATVLWNFTLETVPGHT-VKPKLSIVL 1523 +++ A +L +F ++ PG V+PK VL Sbjct: 464 ELQMALAQILTHFEVQPEPGAAPVRPKTRTVL 495
>Q9VS79:CP4D8_DROME Cytochrome P450 4d8 - Drosophila melanogaster (Fruit fly)| Length = 463 Score = 85.5 bits (210), Expect = 7e-16 Identities = 66/226 (29%), Positives = 111/226 (49%), Gaps = 4/226 (1%) Frame = +3 Query: 897 ICNDDASEHSDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAAR 1076 + ND+ E D F+ F G DTT + LS+ + L +P V+ +L+E+ + Sbjct: 252 LTNDEIREEVDTFM--------FEGHDTTTSALSFCLHELSRHPEVQAKMLEEIVQVLGT 303 Query: 1077 KKVDDMVVLDASELSSMVYLHAALCECLRLYPSVPIT-HKAATHNDVLPSGHE---IKAG 1244 + + + D EL Y+ + E LR+YP VPI K T S H I AG Sbjct: 304 DRSRPVSIRDLGELK---YMECVIKESLRMYPPVPIVGRKLQTDFKYTHSVHGDGVIPAG 360 Query: 1245 DKILVYSYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVA 1424 +I++ + + R + EF PER ++G P+K I F+AGPR C+G++ A Sbjct: 361 SEIIIGIFGVHRQPETFPNPD-EFIPERH--ENGS--RVAPFKMIPFSAGPRNCIGQKFA 415 Query: 1425 FTQMKTVAATVLWNFTLETVPGHTVKPKLSIVLHMKNGLAVTVKRR 1562 +MK + A ++ + L + G V+ ++IVL + G + +++R Sbjct: 416 QLEMKMMLAKIVREYELLPM-GQRVECIVNIVLRSETGFQLGMRKR 460
>Q64459:CP3AB_MOUSE Cytochrome P450 3A11 - Mus musculus (Mouse)| Length = 504 Score = 85.5 bits (210), Expect = 7e-16 Identities = 96/418 (22%), Positives = 162/418 (38%), Gaps = 14/418 (3%) Frame = +3 Query: 303 DPSNVRHIFISNSINYPRGEEYADIFDVLGDGIFNADGESWRRQRAKSQLIMASPRFRSF 482 DP ++++ + + ++ I + + W+R RA + SP F S Sbjct: 86 DPETIKNVLVKECFSVFTNRRDFGPVGIMSKAISISKDDEWKRYRA-----LLSPTFTSG 140 Query: 483 SARCTRDKVERS---LLPFLAHAADVGARCDLHDVLLRLMFDMTCNLVFGVDPGCLQIGL 653 + +E+ L+ +L A G + DVL D+ + FGV+ L Sbjct: 141 KLKEMFPVIEQYGDILVKYLRQKAKKGKPVTMKDVLGAYSMDVITSTSFGVNVDSLNN-- 198 Query: 654 PSLPLARAMD-----DVLETLFLRHVIPPACWRL--MYRYGFGPEKKMAVARRIIDRFAA 812 P P D + L V+ P + M P+ + ++ +DR Sbjct: 199 PEDPFVEKAKKLLRFDFFDPLLFSVVLFPFLTPVYEMLNICMFPKDSIEFFKKFVDRMKE 258 Query: 813 ---DTIVKRRYSGHKLRGEGITESSDILSFFICNDDASEHSDEFLRDTAVNLLFAGRDTT 983 D+ K R +L S D +S SD + ++ +FAG +TT Sbjct: 259 SRLDSKQKHRVDFLQLMMNSHNNSKDKVSH-------KALSDMEITAQSIIFIFAGYETT 311 Query: 984 GAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAALCECLR 1163 + LS+ + L +P +++ + DE+ K + M YL L E LR Sbjct: 312 SSTLSFTLHSLATHPDIQKKLQDEIDEALPNKAPPTY-----DTVMEMEYLDMVLNETLR 366 Query: 1164 LYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWITDD 1343 LYP + DV +G I G +++ SY++ W + EF PER+ ++ Sbjct: 367 LYPIANRLERVCK-KDVELNGVYIPKGSTVMIPSYALHHDPQHWSEP-EEFQPERFSKEN 424 Query: 1344 -GKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLETVPGHTVKPKLS 1514 G + PY ++ F GPR CLG A MK ++ NF+ + + KLS Sbjct: 425 KGSI---DPYVYLPFGNGPRNCLGMRFALMNMKLALTKIMQNFSFQPCKETQIPLKLS 479
>P12394:CP17A_CHICK Cytochrome P450 17A1 - Gallus gallus (Chicken)| Length = 508 Score = 85.5 bits (210), Expect = 7e-16 Identities = 92/396 (23%), Positives = 171/396 (43%), Gaps = 16/396 (4%) Frame = +3 Query: 393 DGIFNADGESWRRQRAKSQLIMASPRFRSFSARCTRDKVERSLLPFLAHAADVGARCDLH 572 D F + G W+ QR ++ S + + SL L A D+ D+ Sbjct: 116 DIAFASYGPLWKFQRKLVHAALSMFGEGSVALEKIICREAASLCETLGAAQDMAL--DMA 173 Query: 573 DVLLRLMFDMTCNLVFGVDPGCLQIGLPSLP-LARAMDDVLETLFLRHVIPPACWRLMYR 749 L R + ++ C+L F + G P + +++T+ ++ W ++ Sbjct: 174 PELTRAVTNVVCSLCFN---SSYRRGDPEFEAMLEYSQGIVDTVAKESLVDIFPWLQIF- 229 Query: 750 YGFGPEKKMAVARRIIDRFAADTIVKRRYSGHK--LRGEGITESSDILSFFICNDDAS-- 917 P + +A+ +R + D +++++++ HK G+ + + D L N + + Sbjct: 230 ----PNRDLALLKRCLK--VRDQLLQQKFTEHKEAFCGDTVRDLMDALLQVRLNAENNSP 283 Query: 918 -----EHSDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMI---LDELAPIAA 1073 E +D+ L T ++ AG +TT VL W L P V++ I +D+ +A Sbjct: 284 LEPGLELTDDHLLMTVGDIFGAGVETTTTVLKWAVLYLLHYPEVQKKIQEEMDQKIGLAR 343 Query: 1074 RKKVDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKI 1253 + D +L YL A + E LR+ P P+ + D + I G ++ Sbjct: 344 HPHLSDRPLLP--------YLEATISEGLRIRPVSPLLIPHVSLADTSIGEYSIPKGARV 395 Query: 1254 LVYSYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQ 1433 ++ +S+ E W K EF+P R++ + G+ H P ++ F AG R CLG+ +A + Sbjct: 396 VINLWSVHHDEKEWDKP-EEFNPGRFLDEQGQHIHSPSPSYLPFGAGIRVCLGEVLAKME 454 Query: 1434 MKTVAATVLWNFTLE---TVPGHTVKPKLSIVLHMK 1532 + A VL FTLE P +++ K +VL ++ Sbjct: 455 LFLFLAWVLQRFTLECPQDQPLPSLEGKFGVVLQVQ 490
>Q9T0K0:C71AJ_ARATH Cytochrome P450 71A19 - Arabidopsis thaliana (Mouse-ear cress)| Length = 490 Score = 85.5 bits (210), Expect = 7e-16 Identities = 106/454 (23%), Positives = 181/454 (39%), Gaps = 21/454 (4%) Frame = +3 Query: 132 KKTTKEE----PTEW--PLLGHL----LSTLANVSNLHDWATGVLATTRYN--FAAHMGL 275 K+TT P+ W P++G+L L+T ++ +L + RY H G Sbjct: 24 KRTTTNNLNLPPSPWRLPVIGNLHQLSLNTHRSLRSL---------SLRYGPLMLLHFGR 74 Query: 276 TGVRFFLTCDPSN-VRHIFISNSINYPRGEEYADIFDVLGDGIFNADGESWRRQRA---- 440 T V + D ++ + + N P+ + I D F GE W++ ++ Sbjct: 75 TPVLIVSSADVAHDILKTYDVICANRPKTKVIDKILRGGRDVAFAPYGEYWKQMKSICIQ 134 Query: 441 ---KSQLIMASPRFRSFSARCTRDKVERSLLPFLAHAADVGARCDLHDVLLRLMFDMTCN 611 ++++ + + R + +KVE A + + +L + + L D+ C Sbjct: 135 NLLSNKMVRSYKKIREDEIKLMIEKVEN------ASSCSPPSPVNLSQLFMTLTNDIICR 188 Query: 612 LVFGVDPGCLQIGLPSLPLARAMDDVLETLFLRHVIPPACWRLMYRYGFGPEKKMAVARR 791 G + G+ + RA ++ + IP W R G + KM + Sbjct: 189 AALGRKYSSKEDGIDVENIVRAFSALVGEFPIGEYIPSLSWIDKIR---GQDHKMEEVDK 245 Query: 792 IIDRFAADTIVKRRYSGHKLRGEGITESSDILSFFICNDDASEHSDEFLRDTAVNLLFAG 971 D F + +VK +K T S + + D S L+ ++ AG Sbjct: 246 RFDEFL-ERVVKEHEDANK-----DTRSDLVDTLLTIQSDKSA-----LKLIIWDMFLAG 294 Query: 972 RDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAALC 1151 T+ + L W L NP+V + + +E+ R + + E M YL A + Sbjct: 295 TATSLSFLEWAMTELMRNPKVMKKLQEEI-----RSSSRQGLFVTEKEAEKMDYLQAVIK 349 Query: 1152 ECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERW 1331 E LRL P P+ DV G+ I AG ++++ ++++ R WG D EF PER Sbjct: 350 EALRLRPPAPLMVPRVFSEDVTLKGYNIPAGTQVIINAWAIQRDTTTWGIDAEEFRPERH 409 Query: 1332 ITDDGKLRHQ-PPYKFIAFNAGPRTCLGKEVAFT 1430 + D L Q +KFI F +G R C G + FT Sbjct: 410 L--DSILDFQGQDFKFIPFGSGKRICPG--IGFT 439
>O49340:C71AC_ARATH Cytochrome P450 71A12 - Arabidopsis thaliana (Mouse-ear cress)| Length = 497 Score = 85.5 bits (210), Expect = 7e-16 Identities = 96/471 (20%), Positives = 186/471 (39%), Gaps = 11/471 (2%) Frame = +3 Query: 90 LVCCFL--SYYRRLQSKKTTKEEPTEWPLLGHLLSTLANVSNLHDWATGVLATTRYNFAA 263 L+ FL + +R +K P PL+G+L + +LH + + RY Sbjct: 14 LITLFLLKQFLKRTANKVNLPPSPWRLPLIGNL-----HQLSLHPHRSLHSLSLRYGPLM 68 Query: 264 HMGLTGVRFFLTCDPSNVRHIFISNSI---NYPRGEEYADIFDVLGDGIFNADGESWRRQ 434 + V + + + ++ + N PR + + + D +F GE WR+ Sbjct: 69 LLHFGRVPILVVSSGEAAQEVLKTHDLKFANRPRSKAVHGLMNGGRDVVFGPYGEYWRQM 128 Query: 435 RAKSQL-IMASPRFRSFSARCTRDKVERSLLPFLAHAADVGARCDLHDVLLRLMFDMTCN 611 ++ L ++ + SF R++ ++ L A+ + +L ++ + L D+T Sbjct: 129 KSVCILNLLTNKMVASFEK--IREEELNEMIKKLEKASSSSSSENLSELFVTLPSDVTSR 186 Query: 612 LVFGVDPGCLQIGLPSLPLARAMDDVLETLFLRHVIPPACWRLMYRYGFGPEKKMAVARR 791 + G + R + ++L + +P W + GF K V++ Sbjct: 187 IALGRKHSEDETARDLKKRVRQIMELLGEFPIGDYVPALAW-IDRINGFNARIK-EVSQG 244 Query: 792 IIDRFAADTIVKRRYSGHKLRGEGIT-----ESSDILSFFICNDDASEHSDEFLRDTAVN 956 D D +V+ + + + ES + F DD ++ ++ Sbjct: 245 FSDLM--DKVVQEHLEAGNHKEDFVDILLSIESEKSIGFQAQRDD--------IKFMILD 294 Query: 957 LLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYL 1136 + G T+ +L W L NP V + + DE+ + ++ +M YL Sbjct: 295 MFIGGTSTSSTLLEWIMTELIRNPNVMKKLQDEIRSTIRPHGS----YIKEKDVENMKYL 350 Query: 1137 HAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEF 1316 A + E R++P +P+ DV G+ I AG ++++ ++++ R +WG D EF Sbjct: 351 KAVIKEVFRVHPPLPLILPRLLSEDVKVKGYNIAAGTEVIINAWAIQRDPAIWGPDAEEF 410 Query: 1317 SPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNF 1469 PER + D H FI F +G R C G +A ++ A ++ F Sbjct: 411 KPERHL-DSTLDYHGKDLNFIPFGSGRRICPGINLALGLVEVTVANLVGRF 460
>P05183:CP3A2_RAT Cytochrome P450 3A2 - Rattus norvegicus (Rat)| Length = 504 Score = 85.1 bits (209), Expect = 9e-16 Identities = 101/424 (23%), Positives = 166/424 (39%), Gaps = 16/424 (3%) Frame = +3 Query: 291 FLTCDPSNVRHIFISNSINYPRGEEYADIFDVLGDGIFNADGESWRRQRAKSQLIMASPR 470 F D ++++ + + ++G + A E W+R RA + SP Sbjct: 82 FAIMDTEMIKNVLVKECFSVFTNRRDFGPVGIMGKAVSVAKDEEWKRYRA-----LLSPT 136 Query: 471 FRSFSARCTRDKVERS---LLPFLAHAADVGARCDLHDVLLRLMFDMTCNLVFGVDPGCL 641 F S + +E+ L+ +L A+ G + V D+ + FGV+ L Sbjct: 137 FTSGRLKEMFPIIEQYGDILVKYLKQEAETGKPVTMKKVFGAYSMDVITSTSFGVNVDSL 196 Query: 642 QIGLPSLPLARAMD-----DVLETLFLRHVIPPACWRL--MYRYGFGPEKKMAVARRIID 800 P P D + LFL V+ P + M P+ +A ++ + Sbjct: 197 NN--PKDPFVEKTKKLLRFDFFDPLFLSVVLFPFLTPIYEMLNICMFPKDSIAFFQKFVH 254 Query: 801 RFAADTIVKRRYSGHKLRGEGITESSDILSFFICNDDASEHSDEFLRDT-----AVNLLF 965 R R S HK R + + L N+ E S + L D +V +F Sbjct: 255 RIKET----RLDSKHKHRVDFLQ-----LMLNAHNNSKDEVSHKALSDVEIIAQSVIFIF 305 Query: 966 AGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAA 1145 AG +TT + LS+ Y L +P +++ + +E+ K ++ M YL Sbjct: 306 AGYETTSSTLSFVLYFLATHPDIQKKLQEEIDGALPSKAPPTYDIV-----MEMEYLDMV 360 Query: 1146 LCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPE 1325 L E LRLYP + + D+ G I G + + +Y++ W K EF PE Sbjct: 361 LNETLRLYP-IGNRLERVCKKDIELDGLFIPKGSVVTIPTYALHHDPQHWPKP-EEFHPE 418 Query: 1326 RWITDD-GKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLETVPGHTVK 1502 R+ ++ G + PY ++ F GPR C+G A MK VL NF+ + + Sbjct: 419 RFSKENKGSI---DPYVYLPFGNGPRNCIGMRFALMNMKLALTKVLQNFSFQPCKETQIP 475 Query: 1503 PKLS 1514 KLS Sbjct: 476 LKLS 479
>Q9VGB5:CP135_DROME Probable cytochrome P450 313a5 - Drosophila melanogaster (Fruit fly)| Length = 487 Score = 85.1 bits (209), Expect = 9e-16 Identities = 93/410 (22%), Positives = 167/410 (40%), Gaps = 5/410 (1%) Frame = +3 Query: 267 MGLTGVRFFLTCDPSNVRHIFISNSINYPRGEEYADIFDVLGDGIFNADGESWRRQRAKS 446 +GLT V +TC+P + IF S + + I LG G+ W +R Sbjct: 72 IGLTPV--LVTCEPKILEDIFTSPNCSNRSSVVDKAISSCLGLGLLTLKNNHWNERRK-- 127 Query: 447 QLIMASPRFRS---FSARCTRDKVERSLLPFLAHAADVGARCDLHDVLLRLMFDMTCNLV 617 + P F++ S + L+ LA D G +L L + F + + Sbjct: 128 ---LLLPSFKNNAVLSFVPVLNNEANFLVTLLAEFVD-GGDINLLPELNKWSFKIAAQIT 183 Query: 618 FGVDPGCLQIGLPSLPLARAMDDVLETLFLRHVIPPACWRLMYRYG--FGPEKKMAVARR 791 G D Q + L + + + + V+P W G F EK+ A Sbjct: 184 MG-DEVRNQANYQNGNLLESYKALNNLIPIGVVMP---WLRNKYLGKLFSYEKRRLEAAT 239 Query: 792 IIDRFAADTIVKRRYSGHKLRGEGITESSDILSFFICNDDASEHSDEFLRDTAVNLLFAG 971 + F D I K KL + ++ + E S + + N++FA Sbjct: 240 QSNAFIKDIIDK------KLSSTDNSSEPALIDRILNLVRIGELSYDDVMGEFSNIIFAA 293 Query: 972 RDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAALC 1151 DT ++ L+ P+ + + +ELA + + ++L +V L L Sbjct: 294 SDTLSITVNNVLILMAMFPKYQDNVFEELAEVFPSGGEFEA---SHADLEKLVKLDRVLH 350 Query: 1152 ECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERW 1331 E +RL P+VP+ + +H+ L +G I G +++ + R + +WG F+P+ + Sbjct: 351 ETMRLIPAVPLLIRQTSHSIQLSNGFYIPEGVTLMIDIFHTHRNKDIWGPQANAFNPDNF 410 Query: 1332 ITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLET 1481 + ++ + R PPY ++ F+ G +TCLG +++ K A +L N+ L T Sbjct: 411 LPENKRAR--PPYSYLPFSKGKKTCLGWKLSLISAKLALAKILRNYMLST 458
>P93703:C71C3_MAIZE Cytochrome P450 71C3 - Zea mays (Maize)| Length = 535 Score = 85.1 bits (209), Expect = 9e-16 Identities = 66/254 (25%), Positives = 118/254 (46%), Gaps = 3/254 (1%) Frame = +3 Query: 813 DTIVKRRYSGHKLRGEGITESSDILSFFICNDDASEHSDEFLRDTAVNLLFAGRDTTGAV 992 + ++ KL G+ ES D + F+ + + + ++ +N+ A +T+ V Sbjct: 279 EEVIHEHVEMRKLSGDKEKESDDFIDIFLSRYEEYGFTMDNVKSLLMNVFEAAIETSYLV 338 Query: 993 LSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAALCECLRLYP 1172 L L + RV + + E+ A KK+D ++ +LSS+ YL A++ E LRL+P Sbjct: 339 LESAMAELMNHRRVMKKLQAEVRAYGAEKKLD---MIREDDLSSLPYLKASMKEALRLHP 395 Query: 1173 SVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWITDDGKL 1352 P+ + D G+ I A ++LV +++GR VW K EF PER++ D Sbjct: 396 PGPLLLPHYSTADCQIDGYHIPANPRVLVNGWAIGRDPAVWEKP-EEFMPERFMRDGWDK 454 Query: 1353 RHQ---PPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLETVPGHTVKPKLSIVL 1523 + ++++ F +G R C G M+ + A ++++F E VP + + Sbjct: 455 SNSYSGQDFRYLPFGSGRRICPGANFGLATMEIMLANLMYHFDWE-VPNEKEDGCWKVSM 513 Query: 1524 HMKNGLAVTVKRRN 1565 K GL + RRN Sbjct: 514 DEKFGLML---RRN 524
>Q9VMS8:C4AC2_DROME Probable cytochrome P450 4ac2 - Drosophila melanogaster (Fruit fly)| Length = 497 Score = 85.1 bits (209), Expect = 9e-16 Identities = 72/300 (24%), Positives = 139/300 (46%), Gaps = 9/300 (3%) Frame = +3 Query: 690 LETLFLRHVIPPACWRLMYRYGFGPEKKMAVARRIIDRFAADTIVKRR--YSGHKLRGE- 860 +E + + + P + ++Y + FG +K +I F+++ I KRR + ++L E Sbjct: 207 IEEVMQQRLCNPFFYNIVYFFLFGDYRKQVNNLKIAHEFSSNIIEKRRSLFKSNQLGQED 266 Query: 861 --GITESSDILSFFICNDDASEHSDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRV 1034 G + +L + + + + + D +F G DTT L + +L + V Sbjct: 267 EFGKKQRYAMLDTLLAAEADGQIDHQGICDEVNTFMFEGYDTTSTCLIFTLLMLALHEDV 326 Query: 1035 EQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDV 1214 ++ +E+ + DD + + + +VY+ + E LRL+PSVP + V Sbjct: 327 QKKCYEEIKYLP-----DDSDDISVFQFNELVYMECVIKESLRLFPSVPFIGRRCVEEGV 381 Query: 1215 LPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAG 1394 + +G + +I ++ Y + R + M F P+R+ ++ RH P+ F+ F+AG Sbjct: 382 V-NGLIMPKNTQINIHLYEIMRDARHFSNPKM-FQPDRFFPENTVNRH--PFAFVPFSAG 437 Query: 1395 PRTCLGKEVAFTQMKTVAATVLWNFTLETVPGHTVKPKLS----IVLHMKNGLAVTVKRR 1562 R C+G++ A ++K + A V+ NF + V T+ L+ IVL K + V + R Sbjct: 438 QRNCIGQKFAILEIKVLLAAVIRNFKILPV---TLLDDLTFENGIVLRTKQNIKVKLVHR 494
>Q09128:CP24A_RAT Cytochrome P450 24A1, mitochondrial precursor - Rattus norvegicus| (Rat) Length = 514 Score = 84.7 bits (208), Expect = 1e-15 Identities = 111/471 (23%), Positives = 187/471 (39%), Gaps = 16/471 (3%) Frame = +3 Query: 138 TTKEEPTEWPLLGHLLSTL--ANVSNLHDWATGVLATTRYNFAAHMGLTGVRFFLTCDPS 311 T+ PT WPLLG LL + HD T +Y M L PS Sbjct: 56 TSLPGPTNWPLLGSLLEIFWKGGLKKQHD--TLAEYHKKYGQIFRMKLGSFDSVHLGSPS 113 Query: 312 NVRHIFISNSINYPRGE-----EYADIFDVLGDGIFNADGESWRRQRAKSQLIMASPRFR 476 + ++ + S + R E Y D + G+ +G+ W+R R+ Q + P Sbjct: 114 LLEALYRTESAHPQRLEIKPWKAYRDHRNE-AYGLMILEGQEWQRVRSAFQKKLMKP--- 169 Query: 477 SFSARCTRDKVERSLLPFLAHAADV----GARCDLHDVLLRLMFDMTCNLVFGVDPGCLQ 644 K+ L FL ++ G DL+ L + F+ C +++ G LQ Sbjct: 170 -VEIMKLDKKINEVLADFLERMDELCDERGRIPDLYSELNKWSFESICLVLYEKRFGLLQ 228 Query: 645 IGLP--SLPLARAMDDVLETLFLRHVIPPACWRLMYRYGFGPEKKMAVARRIIDRFAADT 818 +L A+ ++ T V P + + K+ A + A DT Sbjct: 229 KETEEEALTFITAIKTMMSTFGKMMVTPVELHKRL-------NTKVWQAHTL----AWDT 277 Query: 819 IVK--RRYSGHKLRGEGITESSDILSFFICNDDASEH-SDEFLRDTAVNLLFAGRDTTGA 989 I K + ++L+ +D F+C+ +H S + L L A +TT Sbjct: 278 IFKSVKPCIDNRLQRYSQQPGAD----FLCDIYQQDHLSKKELYAAVTELQLAAVETTAN 333 Query: 990 VLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAALCECLRLY 1169 L W Y L NP+ ++ +L E+ + + D A +L +M YL A L E +RL Sbjct: 334 SLMWILYNLSRNPQAQRRLLQEVQSV-----LPDNQTPRAEDLRNMPYLKACLKESMRLT 388 Query: 1170 PSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWITDDGK 1349 PSVP T + VL + + G + + + +G E + +D +F PERW+ + K Sbjct: 389 PSVPFTTRTLDKPTVL-GEYALPKGTVLTLNTQVLGSSEDNF-EDSHKFRPERWLQKEKK 446 Query: 1350 LRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLETVPGHTVK 1502 + P+ + F G R C+G+ +A Q+ ++ + + V+ Sbjct: 447 IN---PFAHLPFGIGKRMCIGRRLAELQLHLALCWIIQKYDIVATDNEPVE 494
>O08336:CYPE_BACSU Probable bifunctional P-450:NADPH-P450 reductase 2 [Includes:| Cytochrome P450 102 - Bacillus subtilis Length = 1054 Score = 84.3 bits (207), Expect = 1e-15 Identities = 65/231 (28%), Positives = 102/231 (44%), Gaps = 3/231 (1%) Frame = +3 Query: 879 DILSFFICNDD---ASEHSDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMIL 1049 D+LS + D DE +R + L AG +TT +LS+ Y L +P + Sbjct: 235 DLLSLMLYAKDPVTGETLDDENIRYQIITFLIAGHETTSGLLSFAIYCLLTHPEKLKKAQ 294 Query: 1050 DELAPIAARKKVDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGH 1229 +E A R DD + ++ + Y+ L E LRLYP+ P A + VL + Sbjct: 295 EE----ADRVLTDDTP--EYKQIQQLKYIRMVLNETLRLYPTAPAFSLYAKEDTVLGGEY 348 Query: 1230 EIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCL 1409 I G + V + R + WG D +F PER+ D + H + + F G R C+ Sbjct: 349 PISKGQPVTVLIPKLHRDQNAWGPDAEDFRPERF-EDPSSIPH---HAYKPFGNGQRACI 404 Query: 1410 GKEVAFTQMKTVAATVLWNFTLETVPGHTVKPKLSIVLHMKNGLAVTVKRR 1562 G + A + V VL +F L G+ +K K ++ + + +TVK R Sbjct: 405 GMQFALQEATMVLGLVLKHFELINHTGYELKIKEALTI-KPDDFKITVKPR 454
>Q964T2:CP9E2_BLAGE Cytochrome P450 9e2 - Blattella germanica (German cockroach)| Length = 533 Score = 84.3 bits (207), Expect = 1e-15 Identities = 102/433 (23%), Positives = 179/433 (41%), Gaps = 32/433 (7%) Frame = +3 Query: 351 PRGEEYADIFDVLGDGIFNADGESWRRQRA-----------KSQLIMASP---RFRSFSA 488 P EE +F G +FN G W+ R+ K+ ++ S + F Sbjct: 111 PISEEAEPMF---GKNLFNLRGHRWKEMRSTLSPAFTSSKMKNMFVLVSECGKQLGEFLM 167 Query: 489 RCTRDKVERSLLPFLAHAADVGARCDLHDVLLRLMFDMTCNLVFGVDPGCLQIGLPSLPL 668 C+RDK +++ + D+ +L D+ R D+ FG+ GC + P Sbjct: 168 ECSRDKNKKTEGCKIEREGDL-LTVELKDLYTRYTNDVIATSAFGI--GCDSLKNPKNEF 224 Query: 669 ARAMDDVL------ETLFLRHVIPPACWRLMYRYGFGPEKKMAVARRIIDRFAADTIVKR 830 + DV + +FL ++ P RLM K ++ RF + Sbjct: 225 FQMGKDVTNFGGIRQFIFLGYLFSP---RLMKYLNL---KFLSSKATEFFRFLVHNTMDT 278 Query: 831 RYSGHKLRGEGITESSDILSFFICNDDASEHS----------DEFLRDTAVNLLFAGRDT 980 R + +R + I + +++ E + D+ L AV FAG DT Sbjct: 279 RKTKGIIRPDMIHLLMQAKEGTLKSEENGETNGKIASKPKWDDDDLTAQAVLFFFAGFDT 338 Query: 981 TGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAALCECL 1160 +L + +LL NP V+ + DE+ + ++ D + +A + SM YL + E L Sbjct: 339 ASTLLCFMSHLLATNPDVQNRLQDEIDQ--SLEENDGKLTYEA--IHSMKYLDMVVSESL 394 Query: 1161 RLYPSVPITHKAATHNDVLPS--GHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWI 1334 RLYP T + N LP + ++ GD + + Y++ + + + +F PER+ Sbjct: 395 RLYPPAIFTDRKCVKNYRLPMEPSYTLEPGDAVWIPIYAIHH-DPKYYPNPEKFDPERF- 452 Query: 1335 TDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLETVPGHTVKPKLS 1514 +D+ K + P+ ++ F +GPR C+G A + K +L F L+ V + K++ Sbjct: 453 SDENK-DNIKPFTYLPFGSGPRNCIGNRFALMESKIALVHLLCRFNLKVVSKTPIPIKIT 511 Query: 1515 IVLHMKNGLAVTV 1553 K G +TV Sbjct: 512 -----KKGFNMTV 519
>P17177:CP27A_RABIT Cytochrome P450 27, mitochondrial precursor - Oryctolagus cuniculus| (Rabbit) Length = 535 Score = 84.3 bits (207), Expect = 1e-15 Identities = 84/393 (21%), Positives = 156/393 (39%), Gaps = 17/393 (4%) Frame = +3 Query: 360 EEYADIFDVLGDGIFNADGESWRRQRAKSQLIMASPRFRSFSARCTRDKVERSLL---PF 530 +E+ D D L G+F DG W + R + P + + ++ ++ Sbjct: 137 KEHRDHQD-LAYGVFTTDGHDWYQLRQALNQRLLKPAEAALYTDALNEVIDSFVVRLDQL 195 Query: 531 LAHAADVGARCDLHDVLLRLMFDMTCNLVFGVDPGCLQIGLPS----------LPLARAM 680 A +A D+ D+L + C ++F GCL+ +P L ++ Sbjct: 196 RAESASGDQVPDMADLLYHFALEAICYILFEKRIGCLEASIPKDTENFIRSVGLMFQNSV 255 Query: 681 DDVLETLFLRHVIPPACWRLMYRYGFGPEKKMAVARRIIDRFAADTIVKRRYSGHKLRGE 860 + R ++P W+ RY G + + + +ID+ + + + + +G + Sbjct: 256 YVTFLPKWTRPLLP--FWK---RYLDGWDTIFSFGKNLIDQKLQEVVAQLQSAG----SD 306 Query: 861 GITESSDILSFFICNDDASEHSDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQ 1040 G+ S + S + + S + LL AG DTT L+W Y L +NP ++ Sbjct: 307 GVQVSGYLHSLLT----SGQLSPREALGSLPELLLAGVDTTSNTLTWALYHLSKNPEIQA 362 Query: 1041 MILDELAPIAARKKVDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLP 1220 + E+ + A +V + + M L A L E LRLYP +P + ++ Sbjct: 363 ALRKEVVGVVAAGQVP-----QHKDFAHMPLLKAVLKETLRLYPVIPANSRIIVDKEIEV 417 Query: 1221 SGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWI----TDDGKLRHQPPYKFIAFN 1388 G + + Y R + + F P RW+ + K +H P+ + F Sbjct: 418 GGFLFPKNTQFVFCHYVTSRDPSTFSEP-DTFWPYRWLRKGQPETSKTQH--PFGSVPFG 474 Query: 1389 AGPRTCLGKEVAFTQMKTVAATVLWNFTLETVP 1487 G R CLG+ +A +M+ + A ++ + L P Sbjct: 475 YGVRACLGRRIAELEMQLLLARLIQRYELMLAP 507
>Q9VGB3:CP133_DROME Probable cytochrome P450 313a3 - Drosophila melanogaster (Fruit fly)| Length = 492 Score = 84.3 bits (207), Expect = 1e-15 Identities = 106/480 (22%), Positives = 186/480 (38%), Gaps = 7/480 (1%) Frame = +3 Query: 63 MEHWYWFVGLVCCFLSYY----RRLQSKKTTKEEPTEWPLLGHLLSTLANVSNLHDWATG 230 M+ + + + CF Y+ RRL P P+LG L T Sbjct: 1 MDTFQLLLAVGVCFWIYFLWSRRRLYMMHFKIPGPMGLPILGIAFEYLITYKRKMSIRTK 60 Query: 231 VLATTRYNFAAHMGLTGVRFFLTCDPSNVRHIFISNSINYPRGEEYADIFDVLGDGIFNA 410 + +G T F +T DP IF+S + GDG+ + Sbjct: 61 YMDIYGSTCLVWVGPTP--FVITRDPKIAEEIFLSPECLNRSSIFSKPVNSCTGDGLLSL 118 Query: 411 DGESWRRQRAKSQLIMASPRFRSFSARCTRDKVERSLLPFLAHAADVGARCDLHDVLLRL 590 + W +R SF + ++L+ FL G + + D ++R Sbjct: 119 EASKWVDRRKNLNPAFKQNVLLSFLPIFNSEA--KTLVAFLDSLVGQGEK-KVRDDIVRW 175 Query: 591 MFDMTCNLVFGVDPGCLQIGLPSLPLARAMDDVLETLFLRHVIPPACWRLMYRYGFGPEK 770 F + G D + + ++ + ++ + + ++P ++ G G E Sbjct: 176 SFRIATQTTVGTDVK-KDASFKNDSVLKSYETFMKIIVMNVLLPFTHNKIFSTLG-GFET 233 Query: 771 KMAVARRIIDRFAADTIVKRRYSGHKLRGEGITESSDILSFFICNDDASEHSDEFLRDTA 950 + A+A+ +++ + K+ + K E + +++ I E S E ++ Sbjct: 234 QKALAKSNVNKMIGTIVDKKLMT--KPESGSQPEITSVINKAIELHRNGEMSREEVQSEC 291 Query: 951 VNLLFAGRDTTGAVLSWFFYLLCENPRVEQMI---LDELAPIAARKKVDDMVVLDASELS 1121 + + A +TTG + LL P + + L EL P+A D V D +L Sbjct: 292 CSFVVAAFETTGDTVYHALILLAMFPEHQDTVYQELKELFPVAG----DFEVTYD--DLQ 345 Query: 1122 SMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGK 1301 MV+L + E LRL PSVP T + + L SG I G I + ++ R WG Sbjct: 346 RMVFLERVVNETLRLIPSVPFTPRETIRDFRLSSGVVIPKGVGIGIDIFATHRNRDHWGT 405 Query: 1302 DCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLET 1481 D F+P+ ++ D+ + RH PY +I F+ G R C+G + K + +L N + T Sbjct: 406 DPSSFNPDHFLPDNVRDRH--PYAYIPFSKGRRNCIGWKYGLMSSKLALSKILRNCKVST 463
>Q9QZ82:CP11A_MOUSE Cytochrome P450 11A1, mitochondrial precursor - Mus musculus (Mouse)| Length = 526 Score = 84.3 bits (207), Expect = 1e-15 Identities = 58/194 (29%), Positives = 101/194 (52%), Gaps = 1/194 (0%) Frame = +3 Query: 957 LLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMV-Y 1133 +L G DTT L W Y + N +V++M+ E+ +AAR++ D +++ +V Sbjct: 319 MLAGGVDTTSMTLQWNLYEMAHNLKVQEMLRAEV--LAARRQAQG----DMAKMVQLVPL 372 Query: 1134 LHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCME 1313 L A++ E LRL+P + +T + T ND++ ++I A + V S++MGR G + + Sbjct: 373 LKASIKETLRLHP-ISVTLQRYTVNDLVLRNYKIPAKTLVQVASFAMGRDPGFFPNP-NK 430 Query: 1314 FSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLETVPGH 1493 F P RW+ H ++++ F G R CLG+ +A +M + +L NF +E Sbjct: 431 FDPTRWLEKSQNTTH---FRYLGFGWGVRQCLGRRIAELEMTILLINLLENFRIEVQNLR 487 Query: 1494 TVKPKLSIVLHMKN 1535 V K S++L +N Sbjct: 488 DVGTKFSLILMPEN 501
>Q9SAB6:C71AI_ARATH Cytochrome P450 71A18 - Arabidopsis thaliana (Mouse-ear cress)| Length = 497 Score = 84.3 bits (207), Expect = 1e-15 Identities = 96/471 (20%), Positives = 186/471 (39%), Gaps = 11/471 (2%) Frame = +3 Query: 111 YYRRLQSKKTTKEEPTEWPLLGHLLSTLANVSNLHDWATGVLATTRYN--FAAHMGLTGV 284 + +R K P P++G+L + +LH + + RY H G + Sbjct: 23 FLKRTAKKVNLPPSPWRIPVIGNL-----HQLSLHPHRSLHSLSLRYGPLMLLHFGRVPI 77 Query: 285 RFFLTCDPSNVRHIFISNS----INYPRGEEYADIFDVLGDGIFNADGESWRRQRAKSQL 452 L S H + N P+ + + + D +F GE WR+ ++ L Sbjct: 78 ---LVVSSSEAAHEILKTHDLKFANRPKSKAVHGLMNGGRDVVFGPYGEYWRQMKSVCIL 134 Query: 453 -IMASPRFRSFSARCTRDKVERSLLPFLAHAADVGARCDLHDVLLRLMFDMTCNLVFGVD 629 ++ + SF R++ +++ L A+ + +L ++ + L D+T + G Sbjct: 135 NLLTNKMVASFEK--VREEEVNAMMEKLEKASCSSSAENLSELFVTLTSDVTSRVSLGKK 192 Query: 630 PGCLQIGLPSLPLARAMDDVLETLFLRHVIPPACWRLMYRYGFGPEKKMAVARRIIDRFA 809 + R + ++L + +P W + R K + V+R D Sbjct: 193 YWEDETAGGLKKRVRQIMELLREFPIGDYVPALAW--IDRINGFNSKIVEVSRAYSD--- 247 Query: 810 ADTIVKRRYSGHKLRGEGITESSDILSFFICNDDASEHSDEFLRDTA----VNLLFAGRD 977 ++++ H GE +D ++ + + + + R+ +++ G Sbjct: 248 ---LMEKVVQEHLEAGE---HKADFVNILLSIEKEKNNGFKVQRNDIKFMILDMFIGGIS 301 Query: 978 TTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAALCEC 1157 T+ +L W L NP + + +E+ + E+ +M YL A + E Sbjct: 302 TSSTLLEWIMTELIRNPECMKKLQNEIRSTIRPHGS----YIKEKEVENMRYLKAVIKEV 357 Query: 1158 LRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWIT 1337 R++P +P+ DV G++I AG ++L+ ++S+ R +WG D EF PER + Sbjct: 358 FRVHPPLPLILPRLLTEDVKVKGYDIAAGTEVLINAWSIHRDPAIWGPDAEEFKPERHL- 416 Query: 1338 DDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLETVPG 1490 D H K+I F +G R C G +A ++ A ++ F PG Sbjct: 417 DSTLDYHGQDLKYIPFGSGRRICPGINLAMGLVEVTLANLVGRFDWSVDPG 467
>Q6QHT9:CP19A_ANGJA Cytochrome P450 19A1 - Anguilla japonica (Japanese eel)| Length = 511 Score = 84.0 bits (206), Expect = 2e-15 Identities = 87/367 (23%), Positives = 157/367 (42%) Frame = +3 Query: 399 IFNADGESWRRQRAKSQLIMASPRFRSFSARCTRDKVERSLLPFLAHAADVGARCDLHDV 578 IFN + E W++ R + P + A C S L L D+ + D+ ++ Sbjct: 147 IFNNNIELWKKVRTYFAKALTGPGLQRTVAICVAST--DSHLDQLEELTDLSGQVDILNL 204 Query: 579 LLRLMFDMTCNLVFGVDPGCLQIGLPSLPLARAMDDVLETLFLRHVIPPACWRLMYRYGF 758 L + D++ N +F L++ L L + E + P ++ + Y Sbjct: 205 LRCTIVDIS-NQMF------LRVPLNEKELLVKIQKYFEAWQTVLIRPDFLFKFEWMY-- 255 Query: 759 GPEKKMAVARRIIDRFAADTIVKRRYSGHKLRGEGITESSDILSFFICNDDASEHSDEFL 938 K+ A + + K+R + L + +D + I + E S E + Sbjct: 256 ---KEHKEAAHELHEAMEILVEKKRKA---LEEAEKLDDADFATDLIFAQNHGELSAENV 309 Query: 939 RDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASEL 1118 + + ++ A DT L + LL +NP VEQ IL EL + KK ++ S L Sbjct: 310 QQCILEMIIAAPDTMSISLFFMLMLLKQNPEVEQEILKELDTVIGDKKAEN------SNL 363 Query: 1119 SSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWG 1298 ++ + + + E LR +P V T + + +DV+ G+++ G I++ ++GRM Sbjct: 364 QHLIIMESFINESLRYHPVVDFTMRKSLEDDVI-EGYKVFKGTNIIL---NVGRMH---- 415 Query: 1299 KDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLE 1478 C FS + + + P F F +GPR+C+GK ++ MK + AT+L +T+ Sbjct: 416 -KCEFFSKPNEFSLENFEKTVPNRFFQPFGSGPRSCVGKHISMVMMKAILATLLSRYTMC 474 Query: 1479 TVPGHTV 1499 G T+ Sbjct: 475 PRDGRTL 481
>O64635:C76C4_ARATH Cytochrome P450 76C4 - Arabidopsis thaliana (Mouse-ear cress)| Length = 511 Score = 84.0 bits (206), Expect = 2e-15 Identities = 89/395 (22%), Positives = 168/395 (42%), Gaps = 15/395 (3%) Frame = +3 Query: 423 WRRQRAKSQLIMASPRFRSFSARCTRDKVERSLLPFLAHAADVGARCDLHDVLLRLMFDM 602 WR R S +M SP+ R+ + + R K + L+ F+ +++ D+ + ++ Sbjct: 131 WRMLRKLSVTLMFSPQ-RTEATKALRMKKVQELVSFMNESSERKEAVDISRASYTTVLNI 189 Query: 603 TCNLVFGVDPGCLQIGLPSLPLARAMDDVLETLF--LRHVIPPACWRLMYRYGF----GP 764 N++F VD G ++ ++ +T+ + P GF G Sbjct: 190 ISNILFSVDLGSYD--------SKKSNEFQDTVIGAMEAAGKPDAANYFPFMGFLDLQGN 241 Query: 765 EKKM-AVARRIIDRFAADTIVKRRYSGHKLRGEGITESSDILSFFICND-DASEHSDEFL 938 K M + R+ F K + ++ + S I N+ D +E + + Sbjct: 242 RKAMRGLTERLFRVFRGFMDAKIAEKSLGNYSKDVSNRDFLDSLLILNEGDEAELDNNDI 301 Query: 939 RDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASEL 1118 +++ AG DT+ + L W L NP+ E+ + + V + S++ Sbjct: 302 EHLLLDMFTAGTDTSSSTLEWAMAELLRNPKTMVKAQAEMDRVLGQNSV-----VQESDI 356 Query: 1119 SSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWG 1298 S + YL A + E RL+P+ P+ +DV G + ++LV +++GR VW Sbjct: 357 SGLPYLQAVVKETFRLHPAAPLLVPRKAESDVEVLGFMVPKDTQVLVNVWAIGRDPSVW- 415 Query: 1299 KDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLE 1478 ++ +F PER++ D ++ + Y+ F G R C G +A + + A++L++F + Sbjct: 416 ENPSQFEPERFMGKDIDVKGR-DYELTPFGGGRRICPGLPLAVKTVSLMLASLLYSFDWK 474 Query: 1479 TVPGHTVKPKL------SIVLHMKNGL-AVTVKRR 1562 +P V L I LH N L A+ VK++ Sbjct: 475 -LPNGVVSEDLDMDETFGITLHRTNTLYAIPVKKQ 508
>P24465:C71A1_PERAE Cytochrome P450 71A1 - Persea americana (Avocado)| Length = 471 Score = 84.0 bits (206), Expect = 2e-15 Identities = 86/377 (22%), Positives = 159/377 (42%), Gaps = 5/377 (1%) Frame = +3 Query: 375 IFDVLGDGIFNADGESWRRQRAKSQLIMASPRFRSFSARCTRDKVERSLLPFLAHAADVG 554 IF D F+ GE WR+ R L + S + R S R R++ ++ ++ + G Sbjct: 107 IFYDCTDVAFSPYGEYWRQVRKICVLELLSIK-RVNSYRSIREEEVGLMMERISQSCSTG 165 Query: 555 ARCDLHDVLLRLMFDMTCNLVFGVD-PGCLQIGLPSLPLARAMDDVLETLFLRHVIPPAC 731 +L ++LL L + FG G + LA + ++ F+ P Sbjct: 166 EAVNLSELLLLLSSGTITRVAFGKKYEGEEERKNKFADLATELTTLMGAFFVGDYFPSFA 225 Query: 732 WRLMYRYGFGPEKKMAVARRIIDRFAADTIVKRRYSGHKLRGEGITESSDILSFFI-CND 908 W + G + ++ +D F D ++ K G E D++ + Sbjct: 226 WVDVLT---GMDARLKRNHGELDAFV-DHVIDDHLLSRKANGSDGVEQKDLVDVLLHLQK 281 Query: 909 DAS---EHSDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARK 1079 D+S + L+ +++ G DTT L W L ++P V + E+ + +K Sbjct: 282 DSSLGVHLNRNNLKAVILDMFSGGTDTTAVTLEWAMAELIKHPDVMEKAQQEVRRVVGKK 341 Query: 1080 KVDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILV 1259 ++ +L + YL + E LRL+P P+ + DV+ G+ I A ++ + Sbjct: 342 -----AKVEEEDLHQLHYLKLIIKETLRLHPVAPLLVPRESTRDVVIRGYHIPAKTRVFI 396 Query: 1260 YSYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMK 1439 ++++GR W ++ EF PER++ + + Q ++ I F AG R C G + ++ Sbjct: 397 NAWAIGRDPKSW-ENAEEFLPERFVNNSVDFKGQ-DFQLIPFGAGRRGCPGIAFGISSVE 454 Query: 1440 TVAATVLWNFTLETVPG 1490 A +L+ F E +PG Sbjct: 455 ISLANLLYWFNWE-LPG 470
>Q9DBG1:CP27A_MOUSE Cytochrome P450 27, mitochondrial precursor - Mus musculus (Mouse)| Length = 533 Score = 83.6 bits (205), Expect = 3e-15 Identities = 89/383 (23%), Positives = 157/383 (40%), Gaps = 18/383 (4%) Frame = +3 Query: 396 GIFNADGESWR--RQRAKSQLIMASPRFRSFSARCTRDKVERSLLPFLAHAADVGARC-- 563 GIF A GE W RQ K +L+ A D + + F+ V A Sbjct: 147 GIFIAQGEQWYHLRQALKQRLLKPD------EAALYTDALNEVISDFITRLDQVRAESES 200 Query: 564 -----DLHDVLLRLMFDMTCNLVFGVDPGCLQIGLPSLPLA--RAMDDVLETLFLRHVIP 722 D+ +L L + ++F GCL+ +P A R++ + + +P Sbjct: 201 GDQVPDMAHLLYHLALEAITYILFEKRIGCLKPSIPEDTAAFIRSVAIMFQNSVYITFLP 260 Query: 723 PACWRLM---YRYGFGPEKKMAVARRIIDRFAADTIVKRRYSGHKLRGEGITESSDILSF 893 L+ RY G + + +++ID + + + +G +G+ S L F Sbjct: 261 KWTRPLLPFWKRYLNGWDNIFSFGKKLIDEKVQELKAQLQETGP----DGVRVSG-YLHF 315 Query: 894 FICNDDASEHSDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAA 1073 + N+ S T LL AG DTT L+W Y L ++P +++ + E+ + Sbjct: 316 LLTNELLSTQETI---GTFPELLLAGVDTTSNTLTWALYHLSKSPEIQEALHKEVTGVVP 372 Query: 1074 RKKVDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKI 1253 KV + + M L A + E LRLYP VP + T + +G + Sbjct: 373 FGKVP-----QHKDFAHMPLLKAVIKETLRLYPVVPTNSRIITEKETEINGFLFPKNTQF 427 Query: 1254 LVYSYSMGRMEGVWGKDCMEFSPERWI----TDDGKLRHQPPYKFIAFNAGPRTCLGKEV 1421 ++ Y + R V+ + F P RW+ D+ + H P+ + F G R+CLG+ + Sbjct: 428 VLCHYVVSRDPSVF-PEPNSFQPHRWLRKKEADNPGILH--PFGSVPFGYGVRSCLGRRI 484 Query: 1422 AFTQMKTVAATVLWNFTLETVPG 1490 A +M+ + + ++ + + PG Sbjct: 485 AELEMQLMLSRLVQKYEIALAPG 507
>Q9VYT8:C28C1_DROME Probable cytochrome P450 28c1 - Drosophila melanogaster (Fruit fly)| Length = 505 Score = 83.6 bits (205), Expect = 3e-15 Identities = 106/447 (23%), Positives = 182/447 (40%), Gaps = 20/447 (4%) Frame = +3 Query: 294 LTCDPSNVRHIFISNSINYPRGEEYADIFDVLGDGI-----FNADGESWRRQRAKSQLIM 458 L +P V I++S + ++ + + + D+ D + F +GE WR QRA ++ Sbjct: 83 LVLEPRLVYEIYVS-AFSHFENNDASKMVDIAKDRLVALNPFVLEGEEWRHQRAVFSTLL 141 Query: 459 ASPRFRSFSARCTRDKVERSLLPFLAHAADVGARCDLHDVLLRLMFDMTCNLVFGVDPGC 638 + R R+ A R V L F+A + G D D+ LR + + V G+ Sbjct: 142 TNGRIRTTHAIMQR--VCLDLCQFIAIKSAGGKDLDCIDLGLRFTGESLFDCVLGIQART 199 Query: 639 LQIGLPSLPLARAMDDV------LETLFLRHVIPPACWRLMYRYGFGPEKKMAVARRIID 800 LP+ R ++ L H + P R + + V R D Sbjct: 200 FTDN--PLPVVRQNHEMSAENRGLAIAGAVHGLFPNLPRWL---------RPKVFPRSHD 248 Query: 801 RFAADTIVKRRYSGHKLRGEGITESSDILSFFICNDDASEHSDEFLRDTAVNLLFAGRDT 980 RF I + +LR E +D ++ + + S+E + A+ +F G DT Sbjct: 249 RFYGQMISEAL----RLRRSKHQERNDFINHLLEMQRELDLSEEDMASHAMTFMFDGLDT 304 Query: 981 TGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAALCECL 1160 T ++ LL NP ++ + +EL + + D LDA L + YL A E L Sbjct: 305 TSNSIAHCLLLLGRNPDCQRRLYEELQLVNPGGYLPD---LDA--LIDLPYLSACFNESL 359 Query: 1161 RLYPSVPITHKAATHNDVLPSGH-----EIKAGDKILVYSYSMGRMEGVWGKDCMEFSPE 1325 R+YP+ K T L H +++ GD ++V Y++ ++ + + F PE Sbjct: 360 RIYPAGGWASKTCTKEYELRGSHHSEPLKLRPGDHVMVPIYALHNDPDLYPEPDV-FRPE 418 Query: 1326 RWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTL----ETVPGH 1493 R++ D G + F+ F GPR C+G + K A ++ F + T+ G Sbjct: 419 RFL-DGGLKNCKQQGIFLGFGNGPRQCVGMRLGLAMAKAALAAIVQRFEVVVSPRTLNGT 477 Query: 1494 TVKPKLSIVLHMKNGLAVTVKRRNFFT 1574 + P + + +H V R+N T Sbjct: 478 ELDPLIFVGVHKGGIWLQFVPRKNVTT 504
>Q9V8M2:C12B2_DROME Probable cytochrome P450 12b2, mitochondrial precursor - Drosophila| melanogaster (Fruit fly) Length = 561 Score = 83.6 bits (205), Expect = 3e-15 Identities = 94/413 (22%), Positives = 165/413 (39%), Gaps = 18/413 (4%) Frame = +3 Query: 339 SINYPRGEEYADIFDVLGDGIFNADGESWRRQRAKSQLIMAS--------PRFRSFSARC 494 S+NY R D+F +G G+ + G+ W R K ++ P+ S Sbjct: 158 SLNYYRKIHRPDVFKGVG-GLASDQGQEWADIRNKVNPVLMKVQNVRQNLPQLDQISKEF 216 Query: 495 TRDKVERSLLPFLAHAADVGARCDLHDVLLRLMFDMTCNLVFGVDPGCLQIGL-PSLP-L 668 DK+E P H D H+ L F+ + G L P+ L Sbjct: 217 I-DKLETQRNPE-THTLTT----DFHNQLKMWAFESISFVALNTRMGLLSDNPDPNADRL 270 Query: 669 ARAMDDVLETLFLRHVIPPACWRLMYRYGFGPEKKMAVARRIIDRFAADTIVKRRYSGHK 848 A+ M D F + + P+ W GF ++ + + T + Y Sbjct: 271 AKHMRDFFNYSF-QFDVQPSIWTFYKTAGF---------KKFLKTYDNITDITSNYIETA 320 Query: 849 LRGEGITESSDILSFFICNDDASEHSDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENP 1028 +RG G + + EH+ + +++L AG DTT + Y L NP Sbjct: 321 MRGFGKNDDGKTKCVL---EQLLEHNKKVAVTMVMDMLMAGIDTTSSACLTILYHLARNP 377 Query: 1029 RVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHN 1208 ++ + EL I K L +M YL A + E LR+ P + T Sbjct: 378 SKQEKLRRELLRILPTTKDS----LTDQNTKNMPYLRACIKEGLRITSITPGNFRI-TPK 432 Query: 1209 DVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWITDD--------GKLRHQP 1364 D++ SG+++ G +L+ + + + + EF PERW+ D R + Sbjct: 433 DLVLSGYQVPRGTGVLMGVLELSNDDKYFAQSS-EFIPERWLKSDLAPDIQACPAARTRN 491 Query: 1365 PYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLETVPGHTVKPKLSIVL 1523 P+ ++ F GPRTC+GK +A +++T+ +L ++ + +P ++ + +I+L Sbjct: 492 PFVYLPFGFGPRTCIGKRIAELEIETLLVRLLRSYKVSWLPETPIEYESTIIL 544
>O48922:C98A2_SOYBN Cytochrome P450 98A2 - Glycine max (Soybean)| Length = 509 Score = 83.2 bits (204), Expect = 3e-15 Identities = 53/193 (27%), Positives = 96/193 (49%), Gaps = 4/193 (2%) Frame = +3 Query: 942 DTAVNLLF----AGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDA 1109 DT + LL+ AG DTT + W L NPRV+Q + +EL + ++ V+ Sbjct: 288 DTIIGLLWDMITAGMDTTAISVEWAMAELIRNPRVQQKVQEELDRVIGLER-----VMTE 342 Query: 1110 SELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEG 1289 ++ S++ YL E +RL+P P+ + +V G++I G + V +++ R Sbjct: 343 ADFSNLPYLQCVTKEAMRLHPPTPLMLPHRANANVKVGGYDIPKGSNVHVNVWAVARDPA 402 Query: 1290 VWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNF 1469 VW KD +EF PER++ +D ++ ++ + F +G R C G ++ ++ +L +F Sbjct: 403 VW-KDPLEFRPERFLEEDVDMKGH-DFRLLPFGSGRRVCPGAQLGINLAASMLGHLLHHF 460 Query: 1470 TLETVPGHTVKPK 1508 P +KP+ Sbjct: 461 C--WTPPEGMKPE 471
>Q9FLC8:C79A2_ARATH Cytochrome P450 79A2 - Arabidopsis thaliana (Mouse-ear cress)| Length = 529 Score = 83.2 bits (204), Expect = 3e-15 Identities = 69/279 (24%), Positives = 121/279 (43%), Gaps = 4/279 (1%) Frame = +3 Query: 759 GPEKKMAVARRIIDRFAADTIVKRRYSGHKLRGEGITESSDILSFFICNDDASEH---SD 929 G EK ++ A R + ++ D V R + R + E D L FI D SD Sbjct: 257 GHEKVVSNAMRNVSKYN-DPFVDERLM--QWRNGKMKEPQDFLDMFIIAKDTDGKPTLSD 313 Query: 930 EFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDA 1109 E ++ L+ A D W + P + Q ++E+ + + D +V++ Sbjct: 314 EEIKAQVTELMLATVDNPSNAAEWGMAEMINEPSIMQKAVEEIDRVVGK----DRLVIE- 368 Query: 1110 SELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEG 1289 S+L ++ Y+ A + E RL+P P + D + G+ I G +L+ +GR Sbjct: 369 SDLPNLNYVKACVKEAFRLHPVAPFNLPHMSTTDTVVDGYFIPKGSHVLISRMGIGRNPS 428 Query: 1290 VWGKDCMEFSPERWITDDGKL-RHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWN 1466 VW K +F PER ++ + + ++ I+F+AG R C+G ++ + A ++ Sbjct: 429 VWDKP-HKFDPERHLSTNTCVDLNESDLNIISFSAGRRGCMGVDIGSAMTYMLLARLIQG 487 Query: 1467 FTLETVPGHTVKPKLSIVLHMKNGLAVTVKRRNFFTAKP 1583 FT VPG KN + ++ + + F AKP Sbjct: 488 FTWLPVPG-------------KNKIDISESKNDLFMAKP 513
>O44220:C12B1_DROAC Cytochrome P450 12b1, mitochondrial precursor - Drosophila| acanthoptera (Fruit fly) Length = 532 Score = 83.2 bits (204), Expect = 3e-15 Identities = 58/211 (27%), Positives = 102/211 (48%), Gaps = 8/211 (3%) Frame = +3 Query: 948 AVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSM 1127 A+ +L AG DTT + Y L NP ++ + E I D L +M Sbjct: 326 AMYMLMAGIDTTSSAFVTILYHLARNPHKQRQLHRERRRILP----DSDEPLTPENTKNM 381 Query: 1128 VYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDC 1307 YL A + EC+R+ P + AT D++ SG+ + G+ +L+ + E +G+ Sbjct: 382 PYLRACIKECMRITSITPGNFRIAT-KDLVLSGYRVPRGEGVLMGVLELSNSEKYFGQSG 440 Query: 1308 MEFSPERWITDDGK--------LRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLW 1463 +F PERW+ D R + P+ ++AF GPRTC+GK +A +M+T+ +L Sbjct: 441 -QFMPERWLKADTDPDVKACPAARSRNPFVYLAFGFGPRTCIGKRIAELEMETLLTRLLR 499 Query: 1464 NFTLETVPGHTVKPKLSIVLHMKNGLAVTVK 1556 + + + ++ + +I+L +G+ V V+ Sbjct: 500 RYQVSWLAEMPLQYESNIIL-SPHGIYVQVR 529
>Q964T1:CP4CU_BLAGE Cytochrome P450 4c21 - Blattella germanica (German cockroach)| Length = 501 Score = 82.8 bits (203), Expect = 4e-15 Identities = 99/415 (23%), Positives = 167/415 (40%), Gaps = 13/415 (3%) Frame = +3 Query: 279 GVRFFLTCDPSNVRHIFISNSINYPRGEEYADIFDVLGDGIFNADGESWRRQRAKSQLIM 458 G R F+ + + + N+ + Y LG G+ + G W + R ++I Sbjct: 77 GNRPFVNISSPELIEVVLRNTQLIDKAFLYDLFHSWLGTGLLTSSGAKWHQHR---KIIT 133 Query: 459 ASPRFRSFSARCTRDKVERSLLPFLAHAADVG-ARCDLHDVLLRLMFDMTCNLVFGVDPG 635 + F T E+S + +VG + + D+ C G Sbjct: 134 PTFHFSILEGFITIF-AEKSEILVRKLQKEVGRGPFFIRQYVSNCALDIICETAMGTSVN 192 Query: 636 CLQIGLPSLPLA-RAMDDVLETLFLRHVIPPACWRLMYRYGFGPEKKMAVARRIIDRFAA 812 G A M DVL ++ P + Y + +K + ++++ F Sbjct: 193 AQDEGFSEYVTAINKMTDVLSDRMANPLLYPEFIFKLTPYYWTHKKCL----KVLNGFVN 248 Query: 813 DTIVKRRYSGHKLRGEGITESSDI-----LSFFICNDDASEHSDEFLRDTAV-----NLL 962 I +R+ K + +E +DI + F DASE D L DT + + Sbjct: 249 KIIQERKEERKKSKVTQTSEDADIGKKKRVPFLDTLLDASE-DDNKLTDTDILEEVHTFM 307 Query: 963 FAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPI-AARKKVDDMVVLDASELSSMVYLH 1139 F G DT A ++W + L +P +++ E+ I +V M ++L++M YL Sbjct: 308 FEGHDTVSAAMTWLLFELGHHPEIQEEAYKEVQDIFQGSDRVPTM-----ADLNNMNYLE 362 Query: 1140 AALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFS 1319 + E LRL+PSV I H D G+ I AG I + R ++ F+ Sbjct: 363 RVIKESLRLHPSV-IYFVREAHQDFELGGYTIPAGTNIDFSVPFIHRNPEIFPNPRC-FN 420 Query: 1320 PERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLETV 1484 P+ ++ D RH PY +I F+AGPR C+G+ A + K V + +L ++ TV Sbjct: 421 PDNFLPDRVVNRH--PYAYIPFSAGPRNCIGQRFALLEEKVVLSYLLRHYRFRTV 473
>Q9VHP4:CP313_DROME Probable cytochrome P450 313b1 - Drosophila melanogaster (Fruit fly)| Length = 502 Score = 82.8 bits (203), Expect = 4e-15 Identities = 109/500 (21%), Positives = 196/500 (39%), Gaps = 32/500 (6%) Frame = +3 Query: 78 WFVGLVCCFLSYYRRLQSKKTTKEEPTEWPLLGHLLSTLANVSNLHDWATGVLATTRYNF 257 W + FL RR P WPL+G L + N + G+ + F Sbjct: 10 WLLLAWLYFLWSRRRYYKVAWQLRGPIGWPLIGMGLQMM-NPETFLQYMDGLSRQFKAPF 68 Query: 258 AAHMGLTGVRFFLTCDPSNVRHIFISNSINYPRGEEYADIFDVLGDGIFNADGESWRRQR 437 + MG + F DP +V I S +G+ Y + +GDG+F + W + R Sbjct: 69 ISWMGTSC--FLYINDPHSVEQILNSTHCTN-KGDFYRFMSSAIGDGLFTSSSPRWHKHR 125 Query: 438 AKSQLIMASPRFRSFSARCTRDKVERSLLPFLAHAADV------------GARCDLHDVL 581 + +P F ++ + LP A+V G R +++ +L Sbjct: 126 R-----LINPAFGR--------QILSNFLPIFNAEAEVLLQKLELEGVQHGKRLEIYQIL 172 Query: 582 LRLMFDMTCNLVFGVDPGCLQIGLPSLPLARAMDDVLETLFLRHVIPPACWRLMYRYG-- 755 +++ + C G G SL + +A + + E R + P L+YR Sbjct: 173 KKIVLEAACQTTMGKKMNFQHDG--SLCIFKAYNGLTEVCVKRMLSPWLYPDLIYRRSGL 230 Query: 756 FGPEKKMA---------VARRIIDRFAADTIVKRRYSGHKLRGEGITESSDILSFFICND 908 F ++K+ + I+ AA++ ++ S ++RG+ + FI + Sbjct: 231 FRLQQKVVGILFGFIEQLLEPIVSVVAANSNPDQQRSEMEMRGKS-------KAIFI--E 281 Query: 909 DASEHSD------EFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIA 1070 EH + + +RD A + A +TT L + L +P ++ + EL Sbjct: 282 QVREHVERGQLSWQDVRDEANVTIAATFETTSTALYFTILCLAMHPCYQEKLHKELVT-- 339 Query: 1071 ARKKVDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHE---IKA 1241 ++ ++ +L + Y + E +RL+ VP+ ++A + L G I Sbjct: 340 ---ELPPSGDINLEQLQRLEYTEMVINEAMRLFAPVPMVLRSADQDIQLKRGDGEFLIPR 396 Query: 1242 GDKILVYSYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEV 1421 G +I + Y+M R E VWG ++P+ D RH + F+ F G R C+G Sbjct: 397 GTQIGIDIYNMQRDERVWGPLSRTYNPDAHFGLDSPQRH--AFAFVPFTKGLRMCIGYRY 454 Query: 1422 AFTQMKTVAATVLWNFTLET 1481 A MK + A + ++ + T Sbjct: 455 AQMLMKLLLARIFRSYRIST 474
>P56591:CP1A1_SHEEP Cytochrome P450 1A1 - Ovis aries (Sheep)| Length = 519 Score = 82.8 bits (203), Expect = 4e-15 Identities = 55/189 (29%), Positives = 87/189 (46%) Frame = +3 Query: 924 SDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVL 1103 SDE + + ++L AG DT +SW L +PRV++ I +EL + R + + Sbjct: 310 SDEKIINVVMDLFGAGFDTVTTAISWSLLYLVTSPRVQKKIQEELDTVIGRARWPQL--- 366 Query: 1104 DASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRM 1283 S+ + YL A + E R VP T +T D +G I G + V + + Sbjct: 367 --SDRPQLPYLEAFILETFRHSSFVPFTIPHSTTRDTNLNGFYIPKGXCVFVNQWQINHD 424 Query: 1284 EGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLW 1463 + +W +D EF PER++T DG + K I F G R C+G+ +A ++ A +L Sbjct: 425 QKLW-EDPSEFRPERFLTTDGTVNKVLSEKVIIFGLGKRQCIGEIIARLEVFLFLAILLH 483 Query: 1464 NFTLETVPG 1490 PG Sbjct: 484 QVEFHVTPG 492
>P30437:CP17A_ONCMY Cytochrome P450 17A1 - Oncorhynchus mykiss (Rainbow trout) (Salmo| gairdneri) Length = 514 Score = 82.8 bits (203), Expect = 4e-15 Identities = 84/347 (24%), Positives = 146/347 (42%), Gaps = 24/347 (6%) Frame = +3 Query: 555 ARCDLHDVLLRLMFDMTCNLVFGV-----DP---GCLQIGLPSLPLARAMDDVLETLFLR 710 A DL L R + ++ C+L F DP LQ + A D +++ Sbjct: 169 ASLDLSPELTRAVTNVVCSLCFSSSYCRGDPEFEAMLQFSQGIVDTV-AKDSLVDIFPWL 227 Query: 711 HVIPPACWRLMYRYGFGPEKKMAVARRIIDRFAADTIVKRRYSGHKLRGEGITESSDILS 890 V P A RL+ K V+ R D +++++Y HK E D+L Sbjct: 228 QVFPNADLRLL---------KQCVSIR-------DKLLQKKYEEHK-SDYSDHEQRDLLD 270 Query: 891 FFICNDDASEH-------------SDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPR 1031 + ++E+ S++ L T ++ AG +TT VL W L +P+ Sbjct: 271 ALLRAKRSAENNNTAEITMETVGLSEDHLLMTVGDIFGAGVETTSTVLKWAIAYLIHHPQ 330 Query: 1032 VEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHND 1211 V+Q I +EL + + + S+ S+ YL A + E LR+ P P+ D Sbjct: 331 VQQRIQEELDSVVGGDRTPQL-----SDRGSLPYLEATIREVLRIRPVAPLLIPHVAQTD 385 Query: 1212 VLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNA 1391 ++ G +I++ +S+ E W K+ F P R++ ++G P ++ F A Sbjct: 386 TSIGKFTVRKGARIIINLWSLHHDEKEW-KNPEMFDPGRFLNEEGTGLCIPSPSYLPFGA 444 Query: 1392 GPRTCLGKEVAFTQMKTVAATVLWNFTLETVPGH---TVKPKLSIVL 1523 G R CLG+ +A ++ + +L T+ PG +++ K +VL Sbjct: 445 GVRVCLGEALAKMEIFLFLSWILQRLTMTVSPGQPLPSLEGKFGVVL 491
>O64636:C76C1_ARATH Cytochrome P450 76C1 - Arabidopsis thaliana (Mouse-ear cress)| Length = 512 Score = 82.8 bits (203), Expect = 4e-15 Identities = 87/389 (22%), Positives = 161/389 (41%), Gaps = 9/389 (2%) Frame = +3 Query: 423 WRRQRAKSQLIMASPRFRSFSARCTRDKVERSLLPFLAHAADVGARCDLHDVLLRLMFDM 602 WR R S + SP+ R + + R + L+ F++ ++D D+ V ++ Sbjct: 131 WRLLRRLSVTQLLSPQ-RIEATKALRMNKVKELVSFISESSDREESVDISRVAFITTLNI 189 Query: 603 TCNLVFGVDPGCLQIGLPSLPLARAMDDVLETLFLRHVIPPACWRLMYRYGF--GPEKKM 776 N++F VD G + D V+ + A + R+ G K Sbjct: 190 ISNILFSVDLGSYNA---KASINGVQDTVISVMDAAGTPDAANYFPFLRFLDLQGNVKTF 246 Query: 777 AVA-RRIIDRFAADTIVKRRYSGHKLRGEGITESSDILSFFICNDDASEHSDEFLRDTAV 953 V R++ F K + + ++++ + + D SE S + + Sbjct: 247 KVCTERLVRVFRGFIDAKIAEKSSQNNPKDVSKNDFVDNLLDYKGDESELSISDIEHLLL 306 Query: 954 NLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVY 1133 ++ AG DT+ + L W L +NP+ E+ + + + ++ S++S + Y Sbjct: 307 DMFTAGTDTSSSTLEWAMTELLKNPKTMAKAQAEIDCVIGQNGI-----VEESDISKLPY 361 Query: 1134 LHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCME 1313 L A + E RL+ VP+ +D G + ++LV +++GR VW + Sbjct: 362 LQAVVKETFRLHTPVPLLIPRKAESDAEILGFMVLKDTQVLVNVWAIGRDPSVWDNP-SQ 420 Query: 1314 FSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLETVPG- 1490 F PER++ D +R + Y+ F AG R C G +A + + A++L++F + G Sbjct: 421 FEPERFLGKDMDVRGR-DYELTPFGAGRRICPGMPLAMKTVSLMLASLLYSFDWKLPKGV 479 Query: 1491 ----HTVKPKLSIVLHMKNGL-AVTVKRR 1562 + + LH N L AV VK+R Sbjct: 480 LSEDLDMDETFGLTLHKTNPLHAVPVKKR 508
>Q9STL0:C71AN_ARATH Cytochrome P450 71A23 - Arabidopsis thaliana (Mouse-ear cress)| Length = 483 Score = 82.8 bits (203), Expect = 4e-15 Identities = 83/370 (22%), Positives = 149/370 (40%), Gaps = 9/370 (2%) Frame = +3 Query: 414 GESWRRQRAKSQL-IMASPRFRSFSARCTRDKVERSLLPFLAHAADVGARCDLHDVLLRL 590 GE WR+ ++ S L ++++ RSF + E L +L +L L Sbjct: 118 GEYWRQMKSVSVLHLLSNKMVRSFQDV----RQEEITLMMETIRKSSSKPVNLSKILSSL 173 Query: 591 MFDMTCNLVFGVDPGCLQIGLPSLPLARAMDDVLETLFLRHVIPPACWRLMYRYGFGPEK 770 D+ C + G G +G L + L T + +P W + G E Sbjct: 174 TNDVICRVALGRKYG---VGTDFKELIDRLMRQLGTFTIGSYVPWLAWT---DWVSGLEA 227 Query: 771 KMAVARRIIDRFAADTIVKRRYSGHKLRGEGITESSDILSFFICNDDASEHSDEF----- 935 ++ D+ +++R H+ +G + +D + + A++ F Sbjct: 228 RLEKTANDFDK-----LLERIVQDHE---DGDGDKTDFVDVLL----AAQRDKSFGFDID 275 Query: 936 ---LRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLD 1106 ++ ++ G DT+ ++ W L +P + + +E+ I K + Sbjct: 276 RLSIKAIVLDAFVGGTDTSSTLVEWEMTELLRHPTCLKKLQEEVRTICKGKSS-----VS 330 Query: 1107 ASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRME 1286 ++ M YL A + E LRL+P VP+ + DV + I AG +++V +++GR Sbjct: 331 EDDIQGMEYLKAVVKEALRLHPPVPLMVPHQSTQDVRLRDNHIPAGTQVIVNLWAVGREA 390 Query: 1287 GVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWN 1466 WG D EF PER + R Q ++ I F AG R C G A + V A ++ Sbjct: 391 ATWGPDANEFRPERHLESPSDFRGQ-DFELIPFGAGRRMCPGISFAVVLNEVVLANLVHG 449 Query: 1467 FTLETVPGHT 1496 F +++ T Sbjct: 450 FDWQSIDDET 459
>Q92104:CP11B_RANCA Cytochrome P450 11B, mitochondrial precursor - Rana catesbeiana (Bull| frog) Length = 517 Score = 82.4 bits (202), Expect = 6e-15 Identities = 109/457 (23%), Positives = 184/457 (40%), Gaps = 31/457 (6%) Frame = +3 Query: 246 RYNFAAHMGLTGVRFFLTCDPSNVRHIFISNSINYPRGEEYADIFDVLG----------- 392 R N HM L F P + NS+N ++ A +F G Sbjct: 74 RKNSFQHMHLAMEENFQNLGPIYREKLGTHNSVNIMLPQDVARLFQSEGIFPRRMTMEAW 133 Query: 393 ----------DGIFNADGESWRRQRA---KSQLIMAS-PRFRSFSARCTRDKVERSLLPF 530 G+F +GE+WR R K L +A +F F D+ + F Sbjct: 134 SKHRELRNHKQGVFLLNGEAWRSDRIILNKEVLSLAGVKKFLPFL-----DEAAADFVTF 188 Query: 531 LAHAADVGAR----CDLHDVLLRLMFDMTCNLVFGVDPGCLQI--GLPSLPLARAMDDVL 692 + R DL+ L R + + +++G G L+ +L A++ VL Sbjct: 189 MKKRMSKNTRGSLTVDLYADLFRFTLEASSYVLYGQRLGLLEEHPNADTLRFISAVETVL 248 Query: 693 ETLFLRHVIPPACWRLMYRYGFGPEKKMAVARRIIDRFAADTIVKRRYSGHKLRGEGITE 872 +T P +L + + M I ++ AD ++ Y + L E Sbjct: 249 KTTLPLLYYPHQILQLFQTRLWN--EHMHAWDVIFEQ--ADRCIQNIYQEYCLGQE--RG 302 Query: 873 SSDILSFFICNDDASEHSDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILD 1052 S I++ + + S ++ L+ G DTT L + + L NP V++ + + Sbjct: 303 YSGIMAELLLQAELPLDS---IKANITELMAGGVDTTAMPLLFTLFELARNPSVQRELRE 359 Query: 1053 ELAPIAARKKVDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHE 1232 E+ A+ +D+ L L+S+ L A+ E LRLYP V IT + D++ + Sbjct: 360 EIRKAEAQNP-NDLNQL----LNSLPLLKGAIKETLRLYP-VGITVQRHLIKDIVLHNYH 413 Query: 1233 IKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLG 1412 I AG + V Y MGR ++ +D + + P RW+ R +K +AF G R C+G Sbjct: 414 IPAGTLVQVGLYPMGRSPLLF-QDALRYDPARWLK-----REDTNFKALAFGFGSRQCIG 467 Query: 1413 KEVAFTQMKTVAATVLWNFTLETVPGHTVKPKLSIVL 1523 + +A T++ +L NF ++TV +K +L Sbjct: 468 RRIAETEITLFLMHMLKNFQIDTVSKDDIKTVFGFIL 504
>Q9LTM0:C71BN_ARATH Cytochrome P450 71B23 - Arabidopsis thaliana (Mouse-ear cress)| Length = 501 Score = 82.4 bits (202), Expect = 6e-15 Identities = 83/372 (22%), Positives = 158/372 (42%), Gaps = 9/372 (2%) Frame = +3 Query: 414 GESWRRQRAKSQLIMAS-PRFRSFSARCTRDKVERSLLPFLAHAADVGARCDLHDVLLRL 590 GE WR R + + + S +F SF R R++ L+ L+ A++ + +L L L Sbjct: 120 GEEWRALRKLAVIELFSLKKFNSF--RYIREEENDLLVKKLSEASEKQSPVNLKKALFTL 177 Query: 591 MFDMTCNLVFGVDPGCLQ-IGLPSLPLARAMDDVLETLFLRHVIPPACWRLMYRYGFGPE 767 + C L FG + + I S+ + + ++ F P W L + Sbjct: 178 SASIVCRLAFGQNLHESEFIDEDSMEDLASRSEKIQAKFAFSNFFPGGWIL--------D 229 Query: 768 KKMAVARRIIDRFA-ADTIVKRRYSGHKLRGEGITESSDILSFFI------CNDDASEHS 926 K ++ + + FA D + H G + E+ D++ I D + + + Sbjct: 230 KITGQSKSLNEIFADLDGFFNQVLDDHLKPGRKVLETPDVVDVMIDMMNKQSQDGSFKLT 289 Query: 927 DEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLD 1106 + ++ ++ AG +T+ + W L NPRV + + DE+ + K+ D + D Sbjct: 290 TDHIKGIISDIFLAGVNTSATTILWAMTELIRNPRVMKKVQDEVRTVLGEKR-DRITEQD 348 Query: 1107 ASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRME 1286 ++L+ Y + E RL+P+ P+ + G++I +I+V Y++GR Sbjct: 349 LNQLN---YFKLVIKETFRLHPAAPLLLPREAMAKIKIQGYDIPEKTQIMVNVYAIGRDP 405 Query: 1287 GVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWN 1466 +W ++ EF PER++ R ++ + F +G R C G + ++ +L+ Sbjct: 406 DLW-ENPEEFKPERFVDSSVDYRGL-NFELLPFGSGRRICPGMTMGIATVELGLLNLLYF 463 Query: 1467 FTLETVPGHTVK 1502 F G TVK Sbjct: 464 FDWGLPEGRTVK 475
>Q9VFP1:CP6D5_DROME Probable cytochrome P450 6d5 - Drosophila melanogaster (Fruit fly)| Length = 508 Score = 82.0 bits (201), Expect = 7e-15 Identities = 92/392 (23%), Positives = 167/392 (42%), Gaps = 15/392 (3%) Frame = +3 Query: 348 YPRGEEYADIFDVLGDGIFNADGESWRRQRAKSQLIMASPRFRSFSARCTRDKVERSLLP 527 + RG + D + +F +G SWR R K S + ++ T D V L+ Sbjct: 98 HDRGVYVDEKNDPMSASLFQMEGASWRALRNKLTPSFTSGKLKAMFE--TSDSVGDKLVD 155 Query: 528 FLAHA--ADVGARCDLHDVLLRLMFDMTCNLVFGVDPGCL-----QIGLPSLPLARA-MD 683 + A+ +L ++ D+ +FG+D + + S + R ++ Sbjct: 156 SIRKQLPANGAKELELKKLMATYAIDIIATTIFGLDVDSFADPNNEFQIISKKVNRNNIE 215 Query: 684 DVLETLFLRHVIPPACWRLMYRYGF---GPEKKMAVARRIIDRFAADTIVKRRYSGH--K 848 D++ + P + + G+ E+ ++ R +D + IV++ + Sbjct: 216 DIIRGT--SSFLYPGLEKFFVKIGWKQEATERMRELSNRTVDLREQNNIVRKDLLQLLLQ 273 Query: 849 LRGEG-ITESSDILSFFICNDDASEHSDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCEN 1025 LR +G I +I S + S + + AG +TT + S+ Y L +N Sbjct: 274 LRNQGKINTDDNIWSAESTKNGVKSMSKDLIAGQLFLFYVAGYETTASTTSFTLYELTQN 333 Query: 1026 PRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATH 1205 P V + +++ +A +K + DA +S M YL A + E R YP++P+ ++ T Sbjct: 334 PEVMEKAKEDVR--SAIEKHGGKLTYDA--ISDMKYLEACILETARKYPALPLLNRICTK 389 Query: 1206 NDVLPSGH-EIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIA 1382 + +P I+ G I++ M R E + D + + PER++ ++GK Q Y + Sbjct: 390 DYPVPDSKLVIQKGTPIIISLIGMHRDEEYF-PDPLAYKPERYL-ENGKDYTQAAY--LP 445 Query: 1383 FNAGPRTCLGKEVAFTQMKTVAATVLWNFTLE 1478 F GPR C+G + +K A VL NF LE Sbjct: 446 FGEGPRMCIGARMGKVNVKIAIAKVLSNFDLE 477
>Q04552:CP6B1_PAPPO Cytochrome P450 6B1 - Papilio polyxenes (Black swallowtail butterfly)| Length = 498 Score = 82.0 bits (201), Expect = 7e-15 Identities = 97/406 (23%), Positives = 177/406 (43%), Gaps = 18/406 (4%) Frame = +3 Query: 315 VRHIFISNSINYP-RGEEYADIFDVLGDGIFNADGESWRRQRAKSQLIMASPRFRSFSAR 491 ++H+ I + ++ RG E++ D LG IF+ADG+ WR R + + S + +S Sbjct: 88 IKHVLIKDFESFADRGVEFS--LDGLGANIFHADGDRWRSLRNRFTPLFTSGKLKSMLPL 145 Query: 492 CTRDKVERSLLPFLAHAADVGARCDLHDVLLRLMFDMTCNLVFGV--DPGCLQIGLPSLP 665 ++ V + + + +H+++ + VFG+ D G L Sbjct: 146 MSQ--VGDRFINSIDEVSQTQPEQSIHNLVQKFTMTNIAACVFGLNLDEGML-------- 195 Query: 666 LARAMDDVLETLFLRHVIPPACWRLMYRYGFGPEKKM------AVARRIIDRFAADTIVK 827 + ++D+ + +F V A +MY G KK+ V + D + + Sbjct: 196 --KTLEDLDKHIFT--VNYSAELDMMYP---GILKKLNGSLFPKVVSKFFDNLTKNVLEM 248 Query: 828 RRYSGHKLRG-----EGITESSDI-LSFFICNDD--ASEHSDEFLRDTAVNLLFAGRDTT 983 R+ + + + + E + LS N+D A E +D + AG +T+ Sbjct: 249 RKGTPSYQKDMIDLIQELREKKTLELSRKHENEDVKALELTDGVISAQMFIFYMAGYETS 308 Query: 984 GAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAALCECLR 1163 +++ FY L +NP ++ ++ E+ + +R D + + LS M YL E LR Sbjct: 309 ATTMTYLFYELAKNPDIQDKLIAEIDEVLSRH--DGNITYEC--LSEMTYLSKVFDETLR 364 Query: 1164 LYPSVPITHKAATHNDVLPSGH-EIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWITD 1340 YP T + A + V P IK G I+V ++ + + + + + +F PER+ + Sbjct: 365 KYPVADFTQRNAKTDYVFPGTDITIKKGQTIIVSTWGI-QNDPKYYPNPEKFDPERFNPE 423 Query: 1341 DGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLE 1478 + K RH P ++ F+AGPR CLG A Q + VL + +E Sbjct: 424 NVKDRH--PCAYLPFSAGPRNCLGMRFAKWQSEVCIMKVLSKYRVE 467
>P04800:CP3A1_RAT Cytochrome P450 3A1 - Rattus norvegicus (Rat)| Length = 504 Score = 81.6 bits (200), Expect = 1e-14 Identities = 95/422 (22%), Positives = 165/422 (39%), Gaps = 14/422 (3%) Frame = +3 Query: 291 FLTCDPSNVRHIFISNSINYPRGEEYADIFDVLGDGIFNADGESWRRQRAKSQLIMASPR 470 F D ++++ + + ++G + A E W+R RA + SP Sbjct: 82 FAITDTEMIKNVLVKECFSVFTNRRDFGPVGIMGKAVSVAKDEEWKRYRA-----LLSPT 136 Query: 471 FRSFSARCTRDKVERS---LLPFLAHAADVGARCDLHDVLLRLMFDMTCNLVFGVDPGCL 641 F S + +E+ L+ +L A+ G + V D+ + FGV+ L Sbjct: 137 FTSGRLKEMFPIIEQYGDILVKYLKQEAETGKPVTMKKVFGAYSMDVITSTSFGVNVDSL 196 Query: 642 QIGLPSLPLARAMD-----DVLETLFLRHVIPPACWRL--MYRYGFGPEKKMAVARRIID 800 P P D + LFL V+ P + M P+ + ++ + Sbjct: 197 NN--PKDPFVEKTKKLLRFDFFDPLFLSVVLFPFLTPIYEMLNICMFPKDSIEFFKKFVY 254 Query: 801 RFAA---DTIVKRRYSGHKLRGEGITESSDILSFFICNDDASEHSDEFLRDTAVNLLFAG 971 R D++ K R +L +S D + + SD + ++ +FAG Sbjct: 255 RMKETRLDSVQKHRVDFLQLMMNAHNDSKD-------KESHTALSDMEITAQSIIFIFAG 307 Query: 972 RDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAALC 1151 + T + LS+ + L +P ++ + +E+ K + M YL L Sbjct: 308 YEPTSSTLSFVLHSLATHPDTQKKLQEEIDRALPNKAPPTY-----DTVMEMEYLDMVLN 362 Query: 1152 ECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERW 1331 E LRLYP + + DV +G + G +++ SY++ R W + EF PER+ Sbjct: 363 ETLRLYP-IGNRLERVCKKDVEINGVFMPKGSVVMIPSYALHRDPQHWPEP-EEFRPERF 420 Query: 1332 ITDD-GKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLETVPGHTVKPK 1508 ++ G + PY ++ F GPR C+G A MK VL NF+ + + K Sbjct: 421 SKENKGSI---DPYVYLPFGNGPRNCIGMRFALMNMKLALTKVLQNFSFQPCKETQIPLK 477 Query: 1509 LS 1514 LS Sbjct: 478 LS 479
>P14137:CP11A_RAT Cytochrome P450 11A1, mitochondrial precursor - Rattus norvegicus| (Rat) Length = 526 Score = 81.6 bits (200), Expect = 1e-14 Identities = 57/190 (30%), Positives = 98/190 (51%), Gaps = 1/190 (0%) Frame = +3 Query: 957 LLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMV-Y 1133 +L G DTT L W Y + N +V++M+ E+ +AAR++ D +++ +V Sbjct: 320 MLAGGVDTTSMTLQWNLYEMAHNLKVQEMLRAEV--LAARRQAQG----DMAKMVQLVPL 373 Query: 1134 LHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCME 1313 L A++ E LRL+P + +T + ND++ ++I A + V SY+MGR E + + + Sbjct: 374 LKASIKETLRLHP-ISVTLQRYIVNDLVLRNYKIPAKTLVQVASYAMGR-ESSFFPNPNK 431 Query: 1314 FSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLETVPGH 1493 F P RW+ H ++++ F G R CLG+ +A +M VL NF +E Sbjct: 432 FDPTRWLEKSQNTTH---FRYLGFGWGVRQCLGRRIAELEMTIFLINVLENFRIEVQSIR 488 Query: 1494 TVKPKLSIVL 1523 V K +++L Sbjct: 489 DVGTKFNLIL 498
>Q9EPT4:CP11A_MESAU Cytochrome P450 11A1, mitochondrial precursor - Mesocricetus auratus| (Golden hamster) Length = 520 Score = 81.6 bits (200), Expect = 1e-14 Identities = 84/325 (25%), Positives = 150/325 (46%), Gaps = 5/325 (1%) Frame = +3 Query: 564 DLHDVLLRLMFDMTCNLVFGVDPGCLQIGLPSLPLARAMDDVLETLFLRHV----IPPAC 731 D+ D L R F+ ++VFG G L+ + P ++ D + +F V +PP Sbjct: 194 DISDDLFRFAFESITSVVFGERLGMLEEIVD--PESQRFIDAIYQMFHTSVPMLNLPPEL 251 Query: 732 WRLMYRYGFGPEKKMAVARRIIDRFAADTIVKRRYSGHKLRGEGITESSDILSFFICNDD 911 +R + K+ A A +I + AD + Y + + E + S N Sbjct: 252 FRFFRTKTW---KEHAAAWDMIFK-KADDYTQTFYWDLRQKQEFSKYPGVLYSLLGGNKL 307 Query: 912 ASEHSDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVD- 1088 ++ ++ +L G DTT L W Y + N +V++M+ E+ +AAR++ Sbjct: 308 PFKN----IQANITEMLAGGVDTTSMTLQWSLYEMAHNLKVQEMLRAEV--LAARRQAQG 361 Query: 1089 DMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSY 1268 DMV + + + L A++ E LRL+P + +T + +D++ + I A + V +Y Sbjct: 362 DMVKM----VQLVPLLKASIKETLRLHP-ISVTVQRYLVDDLVLRNYRIPAKMLVQVANY 416 Query: 1269 SMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVA 1448 +MGR E + + +F P RW+ H +++++F G R CLG+ +A +M Sbjct: 417 AMGR-EPSFFPNPNKFDPTRWLEKSKNTTH---FRYLSFGWGVRQCLGRRIAELEMTIFL 472 Query: 1449 ATVLWNFTLETVPGHTVKPKLSIVL 1523 VL NF +E H V K +++L Sbjct: 473 INVLENFRIELQSLHDVGTKFNLIL 497
>O22203:C98A3_ARATH Cytochrome P450 98A3 - Arabidopsis thaliana (Mouse-ear cress)| Length = 508 Score = 81.6 bits (200), Expect = 1e-14 Identities = 52/193 (26%), Positives = 94/193 (48%), Gaps = 4/193 (2%) Frame = +3 Query: 942 DTAVNLLF----AGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDA 1109 DT + LL+ AG DTT W + +NPRV+Q + +E + + +L Sbjct: 287 DTIIGLLWDMITAGMDTTAITAEWAMAEMIKNPRVQQKVQEEFDRVVGLDR-----ILTE 341 Query: 1110 SELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEG 1289 ++ S + YL + E RL+P P+ ++ DV G++I G + V +++ R Sbjct: 342 ADFSRLPYLQCVVKESFRLHPPTPLMLPHRSNADVKIGGYDIPKGSNVHVNVWAVARDPA 401 Query: 1290 VWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNF 1469 VW K+ EF PER++ +D ++ ++ + F AG R C G ++ + ++ + +L +F Sbjct: 402 VW-KNPFEFRPERFLEEDVDMKGH-DFRLLPFGAGRRVCPGAQLGINLVTSMMSHLLHHF 459 Query: 1470 TLETVPGHTVKPK 1508 P KP+ Sbjct: 460 V--WTPPQGTKPE 470
>O48927:C78A3_SOYBN Cytochrome P450 78A3 - Glycine max (Soybean)| Length = 523 Score = 81.6 bits (200), Expect = 1e-14 Identities = 68/264 (25%), Positives = 121/264 (45%), Gaps = 7/264 (2%) Frame = +3 Query: 792 IIDRFAADTIVKRRYSGHKLRGEGITESS-DILSFFICNDDASEHSDEFLRDTAVNLLFA 968 +++RF I + R S TE++ D + + + + SD + ++F Sbjct: 272 MVNRFVGTIIAEHRASK--------TETNRDFVDVLLSLPEPDQLSDSDMIAVLWEMIFR 323 Query: 969 GRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAAL 1148 G DT ++ W + +P V+ + +EL + + + + +++ M YL A + Sbjct: 324 GTDTVAVLIEWILARMALHPHVQSKVQEELDAVVGKARA-----VAEDDVAVMTYLPAVV 378 Query: 1149 CECLRLYPSVPITHKA-ATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPE 1325 E LRL+P P+ A + ND G+ + AG +V ++++ R VW KD +EF PE Sbjct: 379 KEVLRLHPPGPLLSWARLSINDTTIDGYHVPAGTTAMVNTWAICRDPHVW-KDPLEFMPE 437 Query: 1326 RWITDDGKLRHQ---PPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLETVPGHT 1496 R++T G + F +G R C GK + + + A++L F E VP Sbjct: 438 RFVTAGGDAEFSILGSDPRLAPFGSGRRACPGKTLGWATVNFWVASLLHEF--EWVPSDE 495 Query: 1497 VKPKLSIVLHMKNGLA--VTVKRR 1562 L+ VL + + +A +TVK R Sbjct: 496 KGVDLTEVLKLSSEMANPLTVKVR 519
>P37122:C76A2_SOLME Cytochrome P450 76A2 - Solanum melongena (Eggplant) (Aubergine)| Length = 505 Score = 81.6 bits (200), Expect = 1e-14 Identities = 63/250 (25%), Positives = 113/250 (45%), Gaps = 6/250 (2%) Frame = +3 Query: 852 RGEGITESSDILSFFI-----CNDDASEHSDEFLRDTAVNLLFAGRDTTGAVLSWFFYLL 1016 R +G + D L + D+ ++ S+ ++ + + AG +TT + + W L Sbjct: 266 RKKGTEKGKDFLDVLLEFQGTGKDEPAKLSEHEIKIFVLEMFLAGTETTSSSVEWALTEL 325 Query: 1017 CENPRVEQMILDELAP-IAARKKVDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHK 1193 +P + E++ I +K +D S++ ++ Y+ A L E LRL+P +P Sbjct: 326 LRHPEAMAKVKTEISQAIEPNRKFED------SDIENLPYMQAVLKESLRLHPPLPFLIP 379 Query: 1194 AATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYK 1373 T D G+++ ++LV ++++GR W D M F PER++ ++ Q Y Sbjct: 380 RETIQDTKFMGYDVPKDTQVLVNAWAIGRDPECW-DDPMSFKPERFLGSKIDVKGQ-HYG 437 Query: 1374 FIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLETVPGHTVKPKLSIVLHMKNGLAVTV 1553 I F AG R C+G + M ++L F E G V PK ++M + VT Sbjct: 438 LIPFGAGRRMCVGLPLGHRMMHFALGSLLREFEWELPDG--VSPK---SINMDGSMGVTA 492 Query: 1554 KRRNFFTAKP 1583 ++R+ P Sbjct: 493 RKRDSLKVIP 502
>Q96581:C75A4_GENTR Flavonoid 3',5'-hydroxylase - Gentiana triflora (Clustered gentian)| Length = 516 Score = 81.6 bits (200), Expect = 1e-14 Identities = 62/230 (26%), Positives = 109/230 (47%), Gaps = 11/230 (4%) Frame = +3 Query: 813 DTIVKRRYSGHKLRGEGITESSDILSFFICNDDASEH---SDEFLRDTAVNLLFAGRDTT 983 D ++ R HK + + D L F I N D S+ + + ++ +NL AG DT+ Sbjct: 255 DVLLTRLLDDHKRTSQERKQKPDFLDFVIANGDNSDGERLNTDNIKALLLNLFTAGTDTS 314 Query: 984 GAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAALCECLR 1163 +++ W L +N + DE+ + R D +L+ S++ ++ YL A E R Sbjct: 315 SSIIEWALAELLKNRTLLTRAQDEMDRVIGR----DRRLLE-SDIPNLPYLQAICKETFR 369 Query: 1164 LYPSVPIT---HKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWI 1334 +PS P+ + H DV +G+ I G ++ V +++GR VWG + EF PER++ Sbjct: 370 KHPSTPLNLPRNCIRGHVDV--NGYYIPKGTRLNVNIWAIGRDPSVWGDNPNEFDPERFL 427 Query: 1335 TD-----DGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNF 1469 D + H ++ I F AG R C G + ++ + T++ +F Sbjct: 428 YGRNAKIDPRGNH---FELIPFGAGRRICAGTRMGILLVEYILGTLVHSF 474
>P20815:CP3A5_HUMAN Cytochrome P450 3A5 - Homo sapiens (Human)| Length = 502 Score = 81.3 bits (199), Expect = 1e-14 Identities = 111/472 (23%), Positives = 175/472 (37%), Gaps = 30/472 (6%) Frame = +3 Query: 153 PTEWPLLGHLLSTLANVSNLHDWATGVLATTRYN--FAAHMGLTGVRFFLTCDPSNVRHI 326 PT PLLG++LS + W +Y + + G V DP +R + Sbjct: 41 PTPLPLLGNVLSYRQGL-----WKFDTECYKKYGKMWGTYEGQLPV--LAITDPDVIRTV 93 Query: 327 FISNSINYPRGEEYADIFDVLGDGIFNADGESWRRQRAKSQLIMASPRFRSFSARCTRDK 506 + + + I A+ E W+R R+ + SP F S + Sbjct: 94 LVKECYSVFTNRRSLGPVGFMKSAISLAEDEEWKRIRS-----LLSPTFTSGKLK----- 143 Query: 507 VERSLLPFLAHAADV-----------GARCDLHDVLLRLMFDMTCNLVFGVDPGCLQIGL 653 + P +A DV G L D+ D+ FGV+ L Sbjct: 144 ---EMFPIIAQYGDVLVRNLRREAEKGKPVTLKDIFGAYSMDVITGTSFGVNIDSLNN-- 198 Query: 654 PSLPLARAMDDVL-----ETLFLRHVIPPACWRLMYRYGFGPEKKMAVARRIIDRFAADT 818 P P + L + LFL ++ P + + F DT Sbjct: 199 PQDPFVESTKKFLKFGFLDPLFLSIILFPFLTPVFEALN-------------VSLFPKDT 245 Query: 819 IVKRRYSGHKLRGEGITESS----DILSFFICNDDASEH------SDEFLRDTAVNLLFA 968 I S ++++ + + D L I + ++ E SD L ++ +FA Sbjct: 246 INFLSKSVNRMKKSRLNDKQKHRLDFLQLMIDSQNSKETESHKALSDLELAAQSIIFIFA 305 Query: 969 GRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVD--DMVVLDASELSSMVYLHA 1142 G +TT +VLS+ Y L +P V+Q + E+ + K D VV M YL Sbjct: 306 GYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNKAPPTYDAVV-------QMEYLDM 358 Query: 1143 ALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSP 1322 + E LRL+P V I + DV +G I G +++ +Y++ W + EF P Sbjct: 359 VVNETLRLFP-VAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEP-EEFRP 416 Query: 1323 ERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLE 1478 ER+ + PY + F GPR C+G A MK VL NF+ + Sbjct: 417 ERFSKKKDSI---DPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFK 465
>Q9VWR5:CP306_DROME Cytochrome P450 306a1 - Drosophila melanogaster (Fruit fly)| Length = 574 Score = 81.3 bits (199), Expect = 1e-14 Identities = 62/216 (28%), Positives = 100/216 (46%), Gaps = 2/216 (0%) Frame = +3 Query: 858 EGITESSDILSFFIC--NDDASEHSDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPR 1031 E E IL F+ + D+ + D+ LR +L AG DT+ A L WF L R Sbjct: 332 EDTYEPECILEHFLAVRDTDSQLYCDDQLRHLLADLFGAGVDTSLATLRWFLLYLAREQR 391 Query: 1032 VEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHND 1211 ++ + + L P+ ++ EL + YL A + E +R+ VP+ + Sbjct: 392 CQRRLHELLLPLGPSPTLE--------ELEPLAYLRACISETMRIRSVVPLGIPHGCKEN 443 Query: 1212 VLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNA 1391 + + IK G I+ +++ M+ V + EF PER++T DG +Q P +FI F++ Sbjct: 444 FVVGDYFIKGGSMIVCSEWAI-HMDPVAFPEPEEFRPERFLTADG--AYQAPPQFIPFSS 500 Query: 1392 GPRTCLGKEVAFTQMKTVAATVLWNFTLETVPGHTV 1499 G R C G+E+A + +L F LE G V Sbjct: 501 GYRMCPGEEMARMILTLFTGRILRRFHLELPSGTEV 536
>P17178:CP27A_RAT Cytochrome P450 27, mitochondrial precursor - Rattus norvegicus (Rat)| Length = 533 Score = 81.3 bits (199), Expect = 1e-14 Identities = 84/382 (21%), Positives = 152/382 (39%), Gaps = 14/382 (3%) Frame = +3 Query: 387 LGDGIFNADGESWRRQRAKSQLIMASPRFRSFSARCTRDKVERSLLPFLAHAADVGARC- 563 L GIF G+ W R M P A D + + F+A V Sbjct: 144 LSYGIFITQGQQWYHLRHSLNQRMLKPA----EAALYTDALNEVISDFIARLDQVRTESA 199 Query: 564 ------DLHDVLLRLMFDMTCNLVFGVDPGCLQIGLP--SLPLARAMDDVLETLFLRHVI 719 D+ +L L + C ++F GCL+ +P + R++ + + + Sbjct: 200 SGDQVPDVAHLLYHLALEAICYILFEKRVGCLEPSIPEDTATFIRSVGLMFKNSVYVTFL 259 Query: 720 PPACWRLM---YRYGFGPEKKMAVARRIIDRFAADTIVKRRYSGHKLRGEGITESSDILS 890 P L+ RY + + ++I + + + + +G +G+ + S L Sbjct: 260 PKWSRPLLPFWKRYMNNWDNIFSFGEKMIHQKVQEIEAQLQAAGP----DGV-QVSGYLH 314 Query: 891 FFICNDDASEHSDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIA 1070 F + + S T L+ AG DTT L+W Y L +NP +++ + E+ + Sbjct: 315 FLLTKELLSPQETV---GTFPELILAGVDTTSNTLTWALYHLSKNPEIQEALHKEVTGVV 371 Query: 1071 ARKKVDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDK 1250 KV + + M L A + E LRLYP VP + T + +G + Sbjct: 372 PFGKVP-----QNKDFAHMPLLKAVIKETLRLYPVVPTNSRIITEKETEINGFLFPKNTQ 426 Query: 1251 ILVYSYSMGRMEGVWGKDCMEFSPERWI--TDDGKLRHQPPYKFIAFNAGPRTCLGKEVA 1424 ++ Y + R V+ + F P RW+ +D Q P+ + F G R+CLG+ +A Sbjct: 427 FVLCHYVVSRDPSVF-PEPESFQPHRWLRKREDDNSGIQHPFGSVPFGYGVRSCLGRRIA 485 Query: 1425 FTQMKTVAATVLWNFTLETVPG 1490 +M+ + + ++ + + PG Sbjct: 486 ELEMQLLLSRLIQKYEVVLSPG 507
>Q6GUR1:CP1A1_MACMU Cytochrome P450 1A1 - Macaca mulatta (Rhesus macaque)| Length = 512 Score = 81.3 bits (199), Expect = 1e-14 Identities = 56/189 (29%), Positives = 86/189 (45%) Frame = +3 Query: 924 SDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVL 1103 SDE + + ++L AG DT +SW L NPRV++ I +EL + R + + Sbjct: 303 SDEKIVNVVLDLFGAGFDTVTTAISWSLMYLVTNPRVQRKIQEELDTVIGRSRRPRL--- 359 Query: 1104 DASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRM 1283 S+ S + Y+ A + E R VP T +T D G I G + V + + Sbjct: 360 --SDRSHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHD 417 Query: 1284 EGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLW 1463 + +W + EF PER+IT DG + K I F G R C+G+ +A ++ A +L Sbjct: 418 QKLW-VNPSEFLPERFITPDGAIDKVLSEKVILFGLGKRKCIGETIARWEVFLFLAILLQ 476 Query: 1464 NFTLETVPG 1490 PG Sbjct: 477 RVEFSVPPG 485
>P33616:CP1A1_MACFA Cytochrome P450 1A1 - Macaca fascicularis (Crab eating macaque)| (Cynomolgus monkey) Length = 512 Score = 81.3 bits (199), Expect = 1e-14 Identities = 56/189 (29%), Positives = 86/189 (45%) Frame = +3 Query: 924 SDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVL 1103 SDE + + ++L AG DT +SW L NPRV++ I +EL + R + + Sbjct: 303 SDEKIVNVVLDLFGAGFDTVTTAISWSLMYLVTNPRVQRKIQEELDTVIGRSRRPRL--- 359 Query: 1104 DASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRM 1283 S+ S + Y+ A + E R VP T +T D G I G + V + + Sbjct: 360 --SDRSHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHD 417 Query: 1284 EGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLW 1463 + +W + EF PER+IT DG + K I F G R C+G+ +A ++ A +L Sbjct: 418 QKLW-VNPSEFLPERFITPDGAIDKVLSEKVILFGLGKRKCIGETIARWEVFLFLAILLQ 476 Query: 1464 NFTLETVPG 1490 PG Sbjct: 477 RVEFSVPPG 485
>P11511:CP19A_HUMAN Cytochrome P450 19A1 - Homo sapiens (Human)| Length = 503 Score = 81.3 bits (199), Expect = 1e-14 Identities = 88/371 (23%), Positives = 158/371 (42%), Gaps = 3/371 (0%) Frame = +3 Query: 399 IFNADGESWRRQRAKSQLIMASPRFRSFSARCTRDKVERSLLPFLAHAADVGARCDLHDV 578 IFN + E W+ R ++ P C ++ L L + D+ + Sbjct: 133 IFNNNPELWKTTRPFFMKALSGPGLVRMVTVCAESL--KTHLDRLEEVTNESGYVDVLTL 190 Query: 579 LLRLMFDMTCNLVFGVDPGCLQIGLPSLPLARAMDDVLETLFLRHVIPPACWRLMYRYGF 758 L R+M D T N +F L+I L + + + + P +++ + Y Sbjct: 191 LRRVMLD-TSNTLF------LRIPLDESAIVVKIQGYFDAWQALLIKPDIFFKISWLYK- 242 Query: 759 GPEKKMAVARRIIDRFAADTIVKRRYSGHKLRGEGITESSDILSFFICNDDASEHSDEFL 938 EK + + I+ A+ +RR S E + E D + I + + + E + Sbjct: 243 KYEKSVKDLKDAIEVLIAEK--RRRISTE----EKLEECMDFATELILAEKRGDLTRENV 296 Query: 939 RDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARK--KVDDMVVLDAS 1112 + +L A DT L + +L+ ++P VE+ I+ E+ + + K+DD+ L Sbjct: 297 NQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGERDIKIDDIQKLKVM 356 Query: 1113 ELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGV 1292 E + +Y E +R P V + + A +DV+ G+ +K G I++ ++GRM Sbjct: 357 E--NFIY------ESMRYQPVVDLVMRKALEDDVI-DGYPVKKGTNIIL---NIGRMHR- 403 Query: 1293 WGKDCMEFSPE-RWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNF 1469 +EF P+ T + ++ P F F GPR C GK +A MK + T+L F Sbjct: 404 -----LEFFPKPNEFTLENFAKNVPYRYFQPFGFGPRGCAGKYIAMVMMKAILVTLLRRF 458 Query: 1470 TLETVPGHTVK 1502 ++T+ G V+ Sbjct: 459 HVKTLQGQCVE 469
>P00185:CP1A1_RAT Cytochrome P450 1A1 - Rattus norvegicus (Rat)| Length = 524 Score = 80.9 bits (198), Expect = 2e-14 Identities = 55/192 (28%), Positives = 84/192 (43%) Frame = +3 Query: 924 SDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVL 1103 SD+ + +L AG DT +SW L NPR+++ I +EL + R + + Sbjct: 307 SDDKVITIVFDLFGAGFDTITTAISWSLMYLVTNPRIQRKIQEELDTVIGRDRQPRL--- 363 Query: 1104 DASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRM 1283 S+ + YL A + E R VP T +T D +G I G + V + + Sbjct: 364 --SDRPQLPYLEAFILETFRHSSFVPFTIPHSTIRDTSLNGFYIPKGHCVFVNQWQVNHD 421 Query: 1284 EGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLW 1463 + +WG D EF PER++T G L K I F G R C+G+ + ++ A +L Sbjct: 422 QELWG-DPNEFRPERFLTSSGTLDKHLSEKVILFGLGKRKCIGETIGRLEVFLFLAILLQ 480 Query: 1464 NFTLETVPGHTV 1499 PG V Sbjct: 481 QMEFNVSPGEKV 492
>P48416:CP10_LYMST Cytochrome P450 10 - Lymnaea stagnalis (Great pond snail)| Length = 545 Score = 80.9 bits (198), Expect = 2e-14 Identities = 93/397 (23%), Positives = 167/397 (42%), Gaps = 8/397 (2%) Frame = +3 Query: 396 GIFNADGESWRRQRAK-SQLIMASPRFRSFSARCTRDKVERSLLPFLAHAADV-GARCDL 569 G+ N+ GE W RQR S+ ++ +FS + +V + L+H D G L Sbjct: 170 GVVNSQGEEWYRQRTVVSKKMLKLAEVSNFSTQM--GEVSDDFVKRLSHVRDSHGEIPAL 227 Query: 570 HDVLLRLMFDMTCNLVFGVDPGCLQIGLPSLPLARAMDDVLETLFLRHVIPPACWRLMYR 749 L + + +F GCL G + P+A+ LE F + P + L Sbjct: 228 ERELFKWAMESIGTFLFEERIGCL--GQETSPMAQTFIANLEGFF--KTLQPLMYNLP-T 282 Query: 750 YGFGPEKKMAVARRIIDRFA--ADTIVKRRYSGHKLRGEGITESSDILSFFICNDDASEH 923 Y K D ++V++++ K+ +T++ ++S+ + N S Sbjct: 283 YKLWSTKLWKQFENYSDNVIDIGRSLVEKKWHPCKME---VTQNLHLISYLVNNGSMSTK 339 Query: 924 SDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVL 1103 + V+L+ A +TT + W Y L +NP+V++ + E+ A+ + Sbjct: 340 E---VTGLIVDLMLAAVETTSSATVWCLYNLAKNPQVQEKLFQEITEAQAKNN----GTI 392 Query: 1104 DASELSSMVYLHAALCECLRLYPSVPITHKAATH--NDVLPSGHEIKAGDKILVYSYSMG 1277 A +L + + A + E LRLY PIT+ + + D+ G+ I AG + Y M Sbjct: 393 SAEDLCKLPMVKAVVKETLRLY---PITYSTSRNIAEDMELGGYTIPAGTHVQANLYGMY 449 Query: 1278 RMEGVWGKDCMEFSPERWITDDGKLRHQ--PPYKFIAFNAGPRTCLGKEVAFTQMKTVAA 1451 R ++ + PERW+ +G + + G R CLG+ +A +M + Sbjct: 450 RDPSLF-PEPEGILPERWLRMNGSQMDATIKSTSQLVWGHGARMCLGRRIAEQEMHITLS 508 Query: 1452 TVLWNFTLETVPGHTVKPKLSIVLHMKNGLAVTVKRR 1562 ++ NFTL + V+P L+ +L + + K R Sbjct: 509 KIIQNFTL-SYNHDDVEPILNTMLTPDRPVRIEFKPR 544
>P37120:C75A2_SOLME Flavonoid 3',5'-hydroxylase - Solanum melongena (Eggplant)| (Aubergine) Length = 513 Score = 80.9 bits (198), Expect = 2e-14 Identities = 54/224 (24%), Positives = 106/224 (47%), Gaps = 5/224 (2%) Frame = +3 Query: 813 DTIVKRRYSGHKLRGEGITESSDILSFFICNDDASEH---SDEFLRDTAVNLLFAGRDTT 983 D ++ + + H+ D L F + N D SE S ++ +NL AG DT+ Sbjct: 250 DDLLTKMFEEHEATSNERKGKPDFLDFIMANRDNSEGERLSITNIKALLLNLFTAGTDTS 309 Query: 984 GAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAALCECLR 1163 +V+ W + +NP + + E+ I + + S++ ++ YL A E R Sbjct: 310 SSVIEWALTEMMKNPTIFKKAQQEMDQIIGKNRR-----FIESDIPNLPYLRAICKEAFR 364 Query: 1164 LYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWITD- 1340 +PS P+ + + G+ I ++ V +++GR VW ++ +EF PER++++ Sbjct: 365 KHPSTPLNLPRVSSDACTIDGYYIPKNTRLSVNIWAIGRDPDVW-ENPLEFIPERFLSEK 423 Query: 1341 DGKLRHQ-PPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNF 1469 + K+ H+ ++ I F AG R C G + ++ + T++ +F Sbjct: 424 NAKIEHRGNDFELIPFGAGRRICAGTRMGIVMVEYILGTLIHSF 467
>P00184:CP1A1_MOUSE Cytochrome P450 1A1 - Mus musculus (Mouse)| Length = 524 Score = 80.5 bits (197), Expect = 2e-14 Identities = 55/192 (28%), Positives = 86/192 (44%) Frame = +3 Query: 924 SDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVL 1103 SD+ + ++L AG DT +SW L NPRV++ I +EL + R + + Sbjct: 307 SDDKVITIVLDLFGAGFDTVTTAISWSLMYLVTNPRVQRKIQEELDTVIGRDRQPRL--- 363 Query: 1104 DASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRM 1283 S+ + YL A + E R VP T +T D +G I G + V + + Sbjct: 364 --SDRPQLPYLEAFILETFRHSSFVPFTIPHSTTRDTSLNGFYIPKGCCVFVNQWQVNHD 421 Query: 1284 EGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLW 1463 +WG D EF PER++T G L + K F G R C+G+ + +++ A +L Sbjct: 422 RELWG-DPNEFRPERFLTPSGTLDKRLSEKVTLFGLGKRKCIGETIGRSEVFLFLAILLQ 480 Query: 1464 NFTLETVPGHTV 1499 + PG V Sbjct: 481 QIEFKVSPGEKV 492
>P58049:C71BB_ARATH Cytochrome P450 71B11 - Arabidopsis thaliana (Mouse-ear cress)| Length = 496 Score = 80.5 bits (197), Expect = 2e-14 Identities = 94/374 (25%), Positives = 157/374 (41%), Gaps = 14/374 (3%) Frame = +3 Query: 423 WRRQRAKSQL-IMASPRFRSFSARCTRDKVERSLLPFLAHAADVGARCDLHDVLLRLMFD 599 WR R + + + + R +SF TR + SL+ F+ AA + +L+ L++L Sbjct: 121 WREVRKMTVVELYTAKRVQSFQH--TRKEEVASLVDFITQAASLEKPVNLNTKLMKLSGS 178 Query: 600 MTCNLVFGVDPGCLQIGLPSLPLARAMDDVLETL------FLRHVIPPACWRLMYRYGFG 761 + C +VFG++ L L ++V++ F P R++ R G Sbjct: 179 VICRVVFGIN-------LKGSKLENLYEEVIQGTMEVVGSFAAADYFPIIGRIIDRIT-G 230 Query: 762 PEKKMAVARRIIDRFAADTIVKRRYSGHKLRGEGITESSDILSFFICNDDASEHSDEF-- 935 K + +D F +I H L E I + DI+ + + EF Sbjct: 231 LHSKCEKIFKAMDAFFDQSIK------HHLEDESIKD--DIIDLLLKMERGEIELGEFQL 282 Query: 936 LRDTAVNLLF----AGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVL 1103 RD +LF AG DT+ V++W L NPRV + E+ + K DD++ Sbjct: 283 TRDNTKGILFNILNAGIDTSAQVMTWVMTYLISNPRVMKKAQAEVREVIKNK--DDIIEE 340 Query: 1104 DASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRM 1283 D L YL + E R+ P VP+ DV G++I I V +++ R Sbjct: 341 DIERLE---YLKMVVKETFRVLPLVPLLIPREASKDVKIGGYDIPKKTWIHVNIWAIHRN 397 Query: 1284 EGVWGKDCMEFSPERWITDDGKLRHQP-PYKFIAFNAGPRTCLGKEVAFTQMKTVAATVL 1460 VW KD F PER++ D ++ ++ ++F+ F +G R C G + + +L Sbjct: 398 PNVW-KDPEAFIPERFM--DNQIDYKGLNFEFLPFGSGRRMCPGIGMGMALVHLTLINLL 454 Query: 1461 WNFTLETVPGHTVK 1502 + F + G V+ Sbjct: 455 YRFDWKLPEGMEVE 468
>Q42716:C71A8_MENPI Cytochrome P450 71A8 - Mentha piperita (Peppermint)| Length = 502 Score = 80.5 bits (197), Expect = 2e-14 Identities = 101/456 (22%), Positives = 191/456 (41%), Gaps = 5/456 (1%) Frame = +3 Query: 126 QSKKTTKEEPTEWPLLGHLLSTLANVS--NLHDWATGVLATTRYNFAAHMGLTGVRFFLT 299 ++K ++ P + P+LG+LL L ++ NL A ++ + L VR + Sbjct: 44 KNKNSSPPSPRKLPILGNLLQ-LGSLPHHNLRSMAR------KHGPIMLLHLGSVRPVSS 96 Query: 300 CDPSNVRHIFISNSINYPRGEEYADIFDVLGDGIFNADGESWRRQRAKSQL-IMASPRFR 476 H + + PRG A + G GE WR+ + + ++++ R + Sbjct: 97 RRRPRGNHENSRSRLRRPRGSRSAAL---QLQGRVGGYGEYWRQLKTICVVQLLSNKRVQ 153 Query: 477 SFSARCTRDKVERSLLPFLAHAADVGARCDLHDVLLRLMFDMTCNLVFGVDPGCL-QIGL 653 SF R R++ E LL + D +L + +L D+ C G G + G Sbjct: 154 SF--RSVREE-ETELL--MKKIGDSSGNVNLSHMFTQLTNDVVCRSAIGRKYGAGDENGE 208 Query: 654 PSLPLARAMDDVLETLFLRHVIPPACWRLMYRYGFGPEKKMAVARRIIDRFAADTIVKRR 833 L + R ++L + + +P + W + GF ++++ + +D F I +R Sbjct: 209 KFLEILREFLELLGAISIGDFVP-SLWWINRINGF--DRRVDRIAKEMDEFLEKVIHERL 265 Query: 834 YSGHKLRGEGITESSDILSFFICNDDASEHSD-EFLRDTAVNLLFAGRDTTGAVLSWFFY 1010 + E DIL N+ A D + ++ +++ AG DTT VL W Sbjct: 266 ENPAAKAEENFV---DILLEIYRNNSAGVSIDRDSIKAIILDVFAAGTDTTAVVLEWAMT 322 Query: 1011 LLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAALCECLRLYPSVPITH 1190 L +P + + + E+ R+ V D + ++ M YL A + E +R + +P+ Sbjct: 323 ELLRHPEIMKKLQSEV-----RQVVKDKHNITDDDIEKMHYLKAVMKETMRFHTPIPLLV 377 Query: 1191 KAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPY 1370 NDV G+++ G +++ ++++GR W + +F PER++ + + Sbjct: 378 PRVARNDVEVMGYDVPVGTMVMINAWAIGRDPTSWDEP-EKFRPERFLNSSVDFKGL-DF 435 Query: 1371 KFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLE 1478 + I F AG R C G ++ A ++ F E Sbjct: 436 ELIPFGAGRRGCPGTTFPMATLEFTLANLMQKFDWE 471
>O08394:CYPD_BACSU Probable bifunctional P-450:NADPH-P450 reductase 1 [Includes:| Cytochrome P450 102 - Bacillus subtilis Length = 1061 Score = 80.1 bits (196), Expect = 3e-14 Identities = 62/228 (27%), Positives = 99/228 (43%), Gaps = 7/228 (3%) Frame = +3 Query: 813 DTIVKRRYSGHKLRGEGITESSDILSFFICNDD---ASEHSDEFLRDTAVNLLFAGRDTT 983 D+I+ R R G + D+L+ + +D + DE +R + L AG +TT Sbjct: 219 DSIIAER------RANGDQDEKDLLARMLNVEDPETGEKLDDENIRFQIITFLIAGHETT 272 Query: 984 GAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDAS----ELSSMVYLHAALC 1151 +LS+ Y L ++P + +E+ D V+ DA+ ++ + Y+ L Sbjct: 273 SGLLSFATYFLLKHPDKLKKAYEEV----------DRVLTDAAPTYKQVLELTYIRMILN 322 Query: 1152 ECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERW 1331 E LRL+P+ P + V+ I D+I V + R WGKD EF PER+ Sbjct: 323 ESLRLWPTAPAFSLYPKEDTVIGGKFPITTNDRISVLIPQLHRDRDAWGKDAEEFRPERF 382 Query: 1332 ITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTL 1475 D P + + F G R C+G + A + V +L FTL Sbjct: 383 EHQD----QVPHHAYKPFGNGQRACIGMQFALHEATLVLGMILKYFTL 426
>O48956:C98A1_SORBI Cytochrome P450 98A1 - Sorghum bicolor (Sorghum) (Sorghum vulgare)| Length = 512 Score = 80.1 bits (196), Expect = 3e-14 Identities = 54/182 (29%), Positives = 98/182 (53%), Gaps = 6/182 (3%) Frame = +3 Query: 942 DTAVNLLF----AGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDA 1109 DT + LL+ AG DTT + W L NPRV++ + +EL + R D V+L+ Sbjct: 290 DTVIGLLWDMITAGMDTTVISVEWAMAELVRNPRVQKKLQEELDRVVGR----DRVMLE- 344 Query: 1110 SELSSMVYLHAALCECLRLYPSVP--ITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRM 1283 ++ ++ YL A + E LRL+P P + HKA+T +V G++I G ++V +++ R Sbjct: 345 TDFQNLPYLQAVVKESLRLHPPTPLMLPHKAST--NVKIGGYDIPKGANVMVNVWAVARD 402 Query: 1284 EGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLW 1463 VW +E+ PER++ ++ ++ ++ + F AG R C G ++ + ++ +L Sbjct: 403 PKVWSNP-LEYRPERFLEENIDIKGS-DFRVLPFGAGRRVCPGAQLGINLVASMIGHLLH 460 Query: 1464 NF 1469 +F Sbjct: 461 HF 462
>Q9SAE3:C71BS_ARATH Cytochrome P450 71B28 - Arabidopsis thaliana (Mouse-ear cress)| Length = 490 Score = 80.1 bits (196), Expect = 3e-14 Identities = 82/362 (22%), Positives = 153/362 (42%), Gaps = 10/362 (2%) Frame = +3 Query: 414 GESWRRQRAKSQL-IMASPRFRSFSARCTRDKVERSLLPFLAHAADVGARCDLHDVLLRL 590 GE WR R S + + +S + +SF R R++ + L+ A + +L L L Sbjct: 117 GEDWRTMRKLSVVELFSSKKLQSF--RYIREEENDLCVKKLSDLASRRSLVNLEKTLFTL 174 Query: 591 MFDMTCNLVFGVD-PGCLQIGLPSLP-LARAMDDVLETLFLRHVIPPACWRLMYRYGFGP 764 + + C + FG++ C + S+ L +DV+ P RL+ + F Sbjct: 175 VGSIVCRIGFGINLRECEFVDEDSIDDLVHKSEDVIRNSIFSDFFPGLMGRLI-EWIFSE 233 Query: 765 EKKMAVARRIIDRFAADTIVKRRYSGHKLRGEGITESSDILSFFIC-------NDDASEH 923 K++ +D F + + G ESSDI+ I D+ + Sbjct: 234 RKRLNRLYSEVDTFFQNILDDHLKPGR--------ESSDIIDVMIDMMKKQEKEGDSFKF 285 Query: 924 SDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVL 1103 + + L+ ++ AG T+ L W L NPRV + + DE+ KK + Sbjct: 286 TTDHLKGMISDIFLAGVGTSSTTLIWAMTELIRNPRVMKKVQDEIRTTLGDKKER----I 341 Query: 1104 DASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRM 1283 +L+ + Y + E RL+P+ P+ T + V G++I A +I++ +Y++ R Sbjct: 342 TEEDLNQLHYFKLMVKEIFRLHPAAPLLLPRETLSHVKIQGYDIPAKTQIMINAYAIARD 401 Query: 1284 EGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLW 1463 +W + EF+P+R++ R ++ + F +G R C G + ++ +L+ Sbjct: 402 PKLW-TNPDEFNPDRFLDSSIDYRGL-NFELLPFGSGRRICPGMTMGIAIVELGLLNLLY 459 Query: 1464 NF 1469 F Sbjct: 460 FF 461
>Q9V676:CP6T3_DROME Probable cytochrome P450 6t3 - Drosophila melanogaster (Fruit fly)| Length = 501 Score = 79.7 bits (195), Expect = 4e-14 Identities = 111/499 (22%), Positives = 188/499 (37%), Gaps = 31/499 (6%) Frame = +3 Query: 78 WFVGLVCCFLSYYRR-----LQSKKTTKEEPTEWPLLGHLLSTLANVSNLHDWATGVLAT 242 W + L L+++ R +S+ P+ W +G+L L + D + A Sbjct: 5 WLLLLTIVTLNFWLRHKYDYFRSRGIPHLPPSSWSPMGNLGQLLFLRISFGDLFRQLYAD 64 Query: 243 TRYNFAAHMG--LTGVRFFLTCDPSNVRHIFISNSINYPRGEEYADIFDVLGDGIFN-AD 413 R A +G + + DP +R + I N N+ E AD D +G A Sbjct: 65 PRNGQAKIVGFFIFQTPALMVRDPELIRQVLIKNFNNFLNRFESADAGDPMGALTLPLAK 124 Query: 414 GESWRRQRAKSQLIMASPRFRSFS-------ARCTRDKVERSLLPFLAHAADVGARCDLH 572 W+ R + S R R A + R L L +G C L+ Sbjct: 125 YHHWKESRQCMSQLFTSGRMRDVMYSQMLDVASDLEQYLNRKLGDRLERVLPLGRMCQLY 184 Query: 573 DVLLRLMFDMTCNLVFGVDPGCLQIGLPSLPLARAMDDVLETLFLRHVIPPACWRLMYRY 752 D+T NL + ++ G L+ G L + +T L + P M + Sbjct: 185 TT------DVTGNLFYSLNVGGLRRGRSEL--------ITKTKELFNTNPRKVLDFMSVF 230 Query: 753 GFGPEKKMAVARRIIDRFAADTIVKRRYSGHKLRGEGITESSDI---LSFFICNDDASEH 923 F P+ + ++ A RY H + D+ L F + ++ + Sbjct: 231 -FLPKWTGVLKPKVFTEDYA------RYMRHLVDDHHEPTKGDLINQLQHFQLSRSSNHY 283 Query: 924 SD--EFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMV 1097 S +F+ A +L AG +T+ A++ + Y L + P +++ + EL R+ Sbjct: 284 SQHPDFVASQAGIILLAGFETSSALMGFTLYELAKAPDIQERLRSEL-----REAFISTA 338 Query: 1098 VLDASELSSMVYLHAALCECLRLYPSVPITHKAAT-----------HNDVLPSGHEIKAG 1244 L L ++ YL E LRLYP+ ++ T H D + + G Sbjct: 339 TLSYDTLMTLPYLKMVCLEALRLYPAAAFVNRECTSSASEGFSLQPHVDFI-----VPPG 393 Query: 1245 DKILVYSYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVA 1424 + + R E W + C+ F PER+ + + RH P +I F AGP C+G + Sbjct: 394 MPAYISILGLHRDERFWPEPCV-FDPERFGPE--RSRHIHPMTYIPFGAGPHGCIGSRLG 450 Query: 1425 FTQMKTVAATVLWNFTLET 1481 Q+K +L + +ET Sbjct: 451 VLQLKLGIVHILKQYWVET 469
>P24463:CP3AC_CANFA Cytochrome P450 3A12 - Canis familiaris (Dog)| Length = 503 Score = 79.7 bits (195), Expect = 4e-14 Identities = 101/429 (23%), Positives = 169/429 (39%), Gaps = 25/429 (5%) Frame = +3 Query: 303 DPSNVRHIFISNSINYPRGEEYADIFDVLGDGIFNADGESWRRQRAKSQLIMASPRFRSF 482 DP ++ + + + + I ++ E W+R R + SP F Sbjct: 86 DPDMIKTVLVKECYSVFTNRRTLGPVGFMKSAISLSEDEEWKRMRT-----LLSPTF--- 137 Query: 483 SARCTRDKVERSLLPFLAHAADV-----------GARCDLHDVLLRLMFDMTCNLVFGVD 629 T K+ + + P + DV G +L DV D+ + FGV+ Sbjct: 138 ----TTGKL-KEMFPIIGQYGDVLVNNLRKEAEKGKAINLKDVFGAYSMDVITSTSFGVN 192 Query: 630 PGCLQIGLPSLPLARAMD-----DVLETLFLRHVIPP---ACWRLMYRYGFGPEKKMAVA 785 L P P D L+ F ++ P + ++ + F P+K Sbjct: 193 IDSLNH--PQDPFVENTKKLLKFDFLDPFFFSILLFPFLTPVFEILNIWLF-PKKVTDFF 249 Query: 786 RRIIDRFAADTIVKRRYSGHKLRGEGITESSDILSFFICNDDASEH------SDEFLRDT 947 R+ ++R + ++ H++ D L I + ++ E SD L Sbjct: 250 RKSVERMKESRLKDKQK--HRV---------DFLQLMINSQNSKEMDTHKALSDLELVAQ 298 Query: 948 AVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSM 1127 ++ +FAG +TT LS+ Y L +P V+Q + +E+ K + DA L M Sbjct: 299 SIIFIFAGYETTSTSLSFLMYELATHPDVQQKLQEEIDATFPNKALP---TYDA--LVQM 353 Query: 1128 VYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDC 1307 YL L E LRLYP + DV SG I G ++V ++++ R + +W + Sbjct: 354 EYLDMVLNETLRLYPIAGRLERVCK-KDVEISGVFIPKGTVVMVPTFTLHRDQSLWPEP- 411 Query: 1308 MEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLETVP 1487 EF PER+ + + PY ++ F GPR C+G A MK VL NF+ + Sbjct: 412 EEFRPERFSRKNKDSIN--PYTYLPFGTGPRNCIGMRFAIMNMKLALVRVLQNFSFKPCK 469 Query: 1488 GHTVKPKLS 1514 + KL+ Sbjct: 470 ETQIPLKLN 478
>Q92113:CP17A_SQUAC Cytochrome P450 17A1 - Squalus acanthias (Spiny dogfish)| Length = 509 Score = 79.7 bits (195), Expect = 4e-14 Identities = 54/237 (22%), Positives = 113/237 (47%), Gaps = 10/237 (4%) Frame = +3 Query: 813 DTIVKRRYSGHKLRGEGITESSDILSFFIC------NDDASEH----SDEFLRDTAVNLL 962 D+I+++++ HK ++D+ + + N+++S H +D+ + T ++ Sbjct: 245 DSILQKKFEDHKANYSS-DSANDLFNILLKAKMNAENNNSSVHEAGLTDDHMVMTVADIF 303 Query: 963 FAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHA 1142 AG +T+ +W L +P V++ I +E+ ++ M S+ +M +L+A Sbjct: 304 GAGVETSSTAFAWMIIYLIHHPEVQKKIQEEIDSNIGFERTPKM-----SDKGNMNFLNA 358 Query: 1143 ALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSP 1322 + E LR+ P P+ D + I G ++++ +++ E W K+ F P Sbjct: 359 TIHEILRIQPVSPLLIPHVALADSSIGDYTIPKGTRVIINLWAIHHDEKEW-KNPDAFDP 417 Query: 1323 ERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLETVPGH 1493 R++ +DGK ++ F AG R CLG+ +A ++ + +L FT++ PG+ Sbjct: 418 GRFLDEDGKYVCSSSESYLPFGAGTRVCLGEMLARMELFLFTSWILQRFTVQVPPGY 474
>Q64410:CP17A_CAVPO Cytochrome P450 17A1 - Cavia porcellus (Guinea pig)| Length = 508 Score = 79.7 bits (195), Expect = 4e-14 Identities = 89/386 (23%), Positives = 167/386 (43%), Gaps = 19/386 (4%) Frame = +3 Query: 390 GDGIFNADGES-WRRQRAKSQLIMASPRFRSFSARCTRDKVERSLLPFLAHAADVGARCD 566 G GI AD + W+ R +L+++S F F R K+E + L+ D A CD Sbjct: 109 GKGIAFADSSATWQLHR---RLVLSS--FSLF--RDGEQKLENIICQELSALCDFLATCD 161 Query: 567 -----LHDVLLRLMFDMTCNLVFGVD--PGCLQIGLPSLPLARAMDDVLETLFLRHVIPP 725 L + + ++ C + F V G +++ + + R + +L +++ Sbjct: 162 GQVKDLSSSIFMTVVNIICMICFSVSYKEGDMEL----VTIRRFTTGFVNSLSDDNLVDI 217 Query: 726 ACWRLMYRYGFGPEKKMAVARRIIDRFAADTIVKRRYSGHKLRGEGITESSDILSFFICN 905 W ++ P K + + R+ + A + K R + ++ D+L N Sbjct: 218 FPWLKIF-----PNKTLEMIRKYTEIRGAMLSKILKECKEKFRSDSVSNLIDLLIQAKVN 272 Query: 906 D---------DASEHSDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDEL 1058 + D++ SD+ + T ++ AG +T+ +V+ W L NP+V++ I +E+ Sbjct: 273 ENNNNSSLDQDSNLFSDKHILTTLGDIFGAGVETSSSVVLWVIAFLLHNPQVKKKIQEEI 332 Query: 1059 APIAARKKVDDMVVLDASELSSMVYLHAALCECLRLYPSVPIT--HKAATHNDVLPSGHE 1232 + S+ + ++ L A + E LR+ P PI HKA T + + Sbjct: 333 DHNVGFSRTPTF-----SDRNHLLMLEATIREVLRIRPVAPILIPHKANTDSSI--GEFA 385 Query: 1233 IKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLG 1412 I +LV +++ E W + +F PER++ G P ++ F AGPR+C+G Sbjct: 386 IDKDTNVLVNLWALHHNEQEWDRPD-QFMPERFLDPTGSQIIVPSSSYLPFGAGPRSCVG 444 Query: 1413 KEVAFTQMKTVAATVLWNFTLETVPG 1490 + +A ++ + A +L F LE G Sbjct: 445 EALARQEIFLITAWLLQKFDLEVPEG 470
>Q43255:C71C2_MAIZE Cytochrome P450 71C2 - Zea mays (Maize)| Length = 536 Score = 79.7 bits (195), Expect = 4e-14 Identities = 57/217 (26%), Positives = 102/217 (47%), Gaps = 5/217 (2%) Frame = +3 Query: 855 GEGITESSDILSFFICNDDASEHSDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRV 1034 GE +D + + + + L+ V++ AG +T+ L + L N V Sbjct: 295 GESEESEADFIHVLLSIQQEYGLTTDNLKAILVDMFEAGIETSYLTLEYGMAELINNRHV 354 Query: 1035 EQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAALCECLRLYPSVP--ITHKAATHN 1208 + + E+ + +L +L SM YL A + E LRL+P P + H + + Sbjct: 355 MEKLQTEVRTTMGSPDGKKLDMLAEEDLGSMPYLKATIKETLRLHPPAPFLLPHYSTADS 414 Query: 1209 DVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWITDDGKL---RHQPPYKFI 1379 ++ G+ + AG ++LV+++++GR W K EF PER++ + G + +FI Sbjct: 415 EI--DGYFVPAGTRVLVHAWALGRDRTTWEKP-EEFMPERFVQEPGAVDVHMKGKDLRFI 471 Query: 1380 AFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLETVPG 1490 F +G R C G F M+ + A ++++F E VPG Sbjct: 472 PFGSGRRICPGMNFGFATMEVMLANLMYHFDWE-VPG 507
>P97720:C11B1_MESAU Cytochrome P450 11B1, mitochondrial precursor - Mesocricetus auratus| (Golden hamster) Length = 499 Score = 79.7 bits (195), Expect = 4e-14 Identities = 97/388 (25%), Positives = 159/388 (40%), Gaps = 9/388 (2%) Frame = +3 Query: 387 LGDGIFNADGESWRRQRAKSQLIMASPR-FRSFSARCTRDKVERSLLPFLAHAADVGARC 563 L G+F +G WR R + M SP+ + F D V R L FL A Sbjct: 125 LSRGVFLLNGPEWRFNRLRINPHMLSPKAVQKFVPMV--DMVARDFLEFLKKKVLANAHG 182 Query: 564 DLHDVLLRLMFDMTCN----LVFGVDPGCL--QIGLPSLPLARAMDDVLETLFLRHVIPP 725 L MF+ T ++FG G L + SL A++ +++T ++P Sbjct: 183 SLSMNFYSSMFNYTIEASHFVLFGERLGLLGDDLNSGSLKFVNALNSIMKTTPQLMLLPS 242 Query: 726 ACWRLMYRYGFGPEKKMAVARRIIDR--FAADTIVKRRYSGHKLRGEGITESSDILSFFI 899 R + V + D F ++ + K + ++ G +S ++S + Sbjct: 243 GLTRWI---------STRVWKENFDSWDFVSEYVTKNVKNVYQEVQSGGPQSWSVISQLV 293 Query: 900 CNDDASEHSDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARK 1079 + + D L ++ + L DTT L + L NP V+Q + E +AA Sbjct: 294 A--EGALTMDAILANS-LELTAGSVDTTSVPLVMTLFELARNPDVQQAVRQE--SLAAEA 348 Query: 1080 KVDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILV 1259 V +S + L A L E LRLYP V + + +D++ + + AG + + Sbjct: 349 SV---AANPQRAMSDLPLLRAVLKETLRLYP-VAVFLERILSSDLVLQNYHVPAGTILHM 404 Query: 1260 YSYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMK 1439 YSMGR V+ + + P+RW+ +G +H + F G R CLGK +A +M Sbjct: 405 SLYSMGRNPAVFPRP-EHYLPQRWLERNGSFQH------LTFGFGVRQCLGKRLAQVEML 457 Query: 1440 TVAATVLWNFTLETVPGHTVKPKLSIVL 1523 + VL +F +ET V+ VL Sbjct: 458 LLLHHVLKSFRVETQEREDVRMVYRFVL 485
>Q9AXM6:T10H_TAXCU Taxane 10-beta-hydroxylase - Taxus cuspidata (Japanese yew)| Length = 497 Score = 79.3 bits (194), Expect = 5e-14 Identities = 84/299 (28%), Positives = 130/299 (43%), Gaps = 4/299 (1%) Frame = +3 Query: 588 LMFDMTCNLVFGVDPGCLQIGLPSLPLARAMDDVLETLFLRHVIPPACWR-LMYRYGFGP 764 L+F + L F V+ G Q + + +LET+ + + P + YR G Sbjct: 194 LIFSIASTLFFDVNDGHQQ---------KQLHHLLETILVGSLSVPLDFPGTRYRKGLQ- 243 Query: 765 EKKMAVARRIIDRFAADTIVKRRYSGHKLRGEGITESSDILSFFICNDDASEHS--DEFL 938 AR +D + I +RR LR ++ D+LS + D +S D+ + Sbjct: 244 ------ARLKLDEILSSLIKRRR---RDLRSGIASDDQDLLSVLLTFRDEKGNSLTDQGI 294 Query: 939 RDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASEL 1118 D + A DTT A ++ F LL NP + + E I KK + + +L Sbjct: 295 LDNFSAMFHASYDTTVAPMALIFKLLYSNPEYHEKVFQEQLEIIGNKKEGEEI--SWKDL 352 Query: 1119 SSMVYLHAALCECLRLYPSV-PITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVW 1295 SM Y A+ E LR+YP V I KA T D+ G+ I G ++L Y+ E + Sbjct: 353 KSMKYTWQAVQESLRMYPPVFGIFRKAIT--DIHYDGYTIPKGWRVLCSPYTTHLREEYF 410 Query: 1296 GKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFT 1472 + EF P R+ D+G RH PY ++ F G RTC G E + ++ + NF+ Sbjct: 411 -PEPEEFRPSRF-EDEG--RHVTPYTYVPFGGGLRTCPGWEFSKIEILLFVHHFVKNFS 465
>Q12609:STCF_EMENI Probable sterigmatocystin biosynthesis P450 monooxygenase stcF -| Emericella nidulans (Aspergillus nidulans) Length = 478 Score = 79.3 bits (194), Expect = 5e-14 Identities = 73/303 (24%), Positives = 136/303 (44%), Gaps = 8/303 (2%) Frame = +3 Query: 594 FDMTCNLVFGVDPGCLQIGLPSLPLARAMDDVLETLFLRHVIPPACWRLMYRYGFGPEKK 773 FD+ +L FG GCL+ + + P ++ ++++ + + + +RL F + Sbjct: 168 FDIIGDLAFGEPFGCLE-RMETNPWIASIQGNVKSIPILNALRR--YRLDRLIEFLAPPR 224 Query: 774 MAVARRIIDRFAADTIVKRRYSGHKLRGEGITESSDILSFFICN--DDASEHSDEFLRDT 947 + RR +F A+ + +R RG D+ + + D S + Sbjct: 225 LLEMRRRNAQFTAEKVDRRLKHATTTRG-------DLWDSVLADPPDGEPPMSRAEMVSN 277 Query: 948 AVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSM 1127 A ++ AG +T+ LS +LL NP Q + + + R + V+DA ++ + Sbjct: 278 ASAIVLAGSETSATTLSGCLWLLLTNPEYLQQLTERI-----RARFSTATVIDAQTVTQI 332 Query: 1128 VYLHAALCECLRLYPSVPITHKAATHNDVLP------SGHEIKAGDKILVYSYSMGRMEG 1289 L A L E LRLYP+VP+ N ++P +G + G + V ++ R Sbjct: 333 QGLQAVLDESLRLYPAVPMQS-----NRIVPPPGARLAGSWVPGGTSVAVQQFAACRSPT 387 Query: 1290 VWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNF 1469 + + EF PERW +G+ + F+ GPR C+G+++A +M+ + +LW+F Sbjct: 388 NFHRPD-EFIPERW-EKEGEFINDRREASQPFSIGPRNCIGRQLALAEMRLILVHLLWHF 445 Query: 1470 TLE 1478 +E Sbjct: 446 DIE 448
>P17549:CP53_ASPNG Benzoate 4-monooxygenase - Aspergillus niger| Length = 517 Score = 79.3 bits (194), Expect = 5e-14 Identities = 62/211 (29%), Positives = 94/211 (44%), Gaps = 6/211 (2%) Frame = +3 Query: 948 AVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMI---LDELAPIAARKKVDDMVVLDASEL 1118 A+ L AG DTT Y P V + + LDE P D+ V + + Sbjct: 312 ALTQLIAGSDTTSNTSCAILYWCMRTPGVIEKLHKALDEAIP-------QDVDVPTHAMV 364 Query: 1119 SSMVYLHAALCECLRLYPSVPI---THKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEG 1289 + YL + E +R++ + + A + V SGH GD + V SY++ R + Sbjct: 365 KDIPYLQWVIWETMRIHSTSAMGLPREIPAGNPPVTISGHTFYPGDVVSVPSYTIHRSKE 424 Query: 1290 VWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNF 1469 +WG D +F PERW D +L + FI F+ GPR C+G+ VA ++ + TV F Sbjct: 425 IWGPDAEQFVPERW--DPARLTPRQKAAFIPFSTGPRACVGRNVAEMELLVICGTVFRLF 482 Query: 1470 TLETVPGHTVKPKLSIVLHMKNGLAVTVKRR 1562 E ++ + L GL V +KRR Sbjct: 483 EFEMQQEGPMETREGF-LRKPLGLQVGMKRR 512
>P56590:CP1A1_CANFA Cytochrome P450 1A1 - Canis familiaris (Dog)| Length = 524 Score = 79.3 bits (194), Expect = 5e-14 Identities = 53/179 (29%), Positives = 82/179 (45%) Frame = +3 Query: 924 SDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVL 1103 SDE + + ++L AG DT +SW L NP V++ I EL + R + + Sbjct: 307 SDEKIVNVVLDLFGAGFDTVTTAISWSLLYLVTNPNVQKKIQKELDTVIGRARQPRL--- 363 Query: 1104 DASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRM 1283 S+ + Y+ A + E R VP T +T D SG I G + V + + Sbjct: 364 --SDRPQLPYMEAFILETFRHASFVPFTIPHSTTRDTSLSGFYIPKGRCVFVNQWQINHD 421 Query: 1284 EGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVL 1460 + +WG EF PER++T DG + K I F G R C+G+ +A ++ A +L Sbjct: 422 QKLWGNPS-EFQPERFLTLDGTINKALSEKVILFGLGKRKCIGETIARLEVFLFLAILL 479
>O81973:C93A3_SOYBN Cytochrome P450 93A3 - Glycine max (Soybean)| Length = 510 Score = 79.3 bits (194), Expect = 5e-14 Identities = 63/246 (25%), Positives = 122/246 (49%), Gaps = 9/246 (3%) Frame = +3 Query: 759 GPEKKMAVARRIIDRFAADTIVKRRYSGHKLRGE--GITESSDILS--FFICNDDASEH- 923 G K++ R D D I+K+R + + E G E D+L F I D++SE Sbjct: 233 GFNKRLEKIRDCFDT-VLDRIIKQREEERRNKNETVGKREFKDMLDVLFDISEDESSEIK 291 Query: 924 -SDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVV 1100 + E ++ +++L AG DT+ + W L NP V + E+ + + + + Sbjct: 292 LNKENIKAFILDILIAGTDTSAVTMEWAMAELINNPGVLEKARQEMDAVVGKSR-----I 346 Query: 1101 LDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGR 1280 ++ S+++++ YL + E LRL+P+ P+ + ++ V+ G++I A ++ V +++GR Sbjct: 347 VEESDIANLPYLQGIVRETLRLHPAGPLLFRESSRRAVV-CGYDIPAKTRLFVNVWAIGR 405 Query: 1281 MEGVWGKDCMEFSPERWITDDGKLR---HQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAA 1451 W ++ +EF PER++ ++GK + Y + F +G R C G +A + A Sbjct: 406 DPNHW-ENPLEFRPERFV-ENGKSQLDVRGQHYHLLPFGSGRRACPGTSLALQVVHVNLA 463 Query: 1452 TVLWNF 1469 ++ F Sbjct: 464 VLIQCF 469
>O64637:C76C2_ARATH Cytochrome P450 76C2 - Arabidopsis thaliana (Mouse-ear cress)| Length = 512 Score = 79.3 bits (194), Expect = 5e-14 Identities = 92/398 (23%), Positives = 165/398 (41%), Gaps = 18/398 (4%) Frame = +3 Query: 423 WRRQRAKSQLIMASPRFRSFSARCTRDKVERSLLPFLAHAADVGARCDLHDVLLRLMFDM 602 WR R S + SP+ R + + R+ + L+ F++ +++ D+ ++ Sbjct: 131 WRLLRKLSATQLFSPQ-RIEATKTLRENKVKELVSFMSESSEREEAVDISRATFITALNI 189 Query: 603 TCNLVFGVDPGCLQIGLPSLPLARAMDDVLETLFLRHVIPPACWRLMYRYGF-------- 758 N++F VD G S D V+ + V P GF Sbjct: 190 ISNILFSVDLG----NYDSNKSGVFQDTVIGVM--EAVGNPDAANFFPFLGFLDLQGNRK 243 Query: 759 ----GPEKKMAVARRIIDRFAADTIVKRRYSGHKLRGEGITESSDILSFFICNDDASEHS 926 E+ V R ID A+ ++ S + + D+L D+A ++ Sbjct: 244 TLKACSERLFKVFRGFIDAKLAEKSLRDTNSKDVRERDFV----DVLLDLTEGDEAELNT 299 Query: 927 DEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLD 1106 ++ + ++L AG DT + + W L NP E+ + +K V ++ Sbjct: 300 NDIVH-LLLDLFGAGTDTNSSTVEWAMAELLRNPETMVKAQAEIDCVIGQKGV-----VE 353 Query: 1107 ASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRME 1286 S++S++ YL A + E RL+P+ P+ +DV G + ++ V +++GR Sbjct: 354 ESDISALPYLQAVVKETFRLHPAAPLLVPRKAESDVEVLGFMVPKDTQVFVNVWAIGRDP 413 Query: 1287 GVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWN 1466 VW ++ F PER++ D LR + Y+ F AG R C G +A + + A++L++ Sbjct: 414 NVW-ENSSRFKPERFLGKDIDLRGR-DYELTPFGAGRRICPGLPLAVKTVPLMLASLLYS 471 Query: 1467 FTLETVPG-----HTVKPKLSIVLHMKNGL-AVTVKRR 1562 F + G + + LH N L AV VK+R Sbjct: 472 FDWKLPNGVGSEDLDMDETFGLTLHKTNPLHAVPVKKR 509
>O81974:C71D8_SOYBN Cytochrome P450 71D8 - Glycine max (Soybean)| Length = 504 Score = 79.3 bits (194), Expect = 5e-14 Identities = 114/500 (22%), Positives = 212/500 (42%), Gaps = 20/500 (4%) Frame = +3 Query: 126 QSKKTTKEEPTEW--PLLGHLLSTLANVSNLHDWATGVLATTRYNFAAHMGLTGVRFFLT 299 + K + K P W P++G+L LA ++L D A L +Y H+ L + + Sbjct: 26 KQKSSHKLPPGPWRLPIIGNL-HQLALAASLPDQALQKLVR-KYGPLMHLQLGEISTLVV 83 Query: 300 CDPSNVRHIFISNSINY-PRGEEYADIFDVLG--DGIFNADGESWRRQRAKSQL-IMASP 467 P + ++ +++ R + A F V G D F G+ WR+ R L ++++ Sbjct: 84 SSPKMAMEMMKTHDVHFVQRPQLLAPQFMVYGATDIAFAPYGDYWRQIRKICTLELLSAK 143 Query: 468 RFRSFSARCTRDKVERSLLPFLAHAADVGARCDLHDVLLRLMFDMTCNLVFGVDPGCLQI 647 R +SFS R + L+ + +A G+ DL L L+ FG + Sbjct: 144 RVQSFSH--IRQDENKKLIQSIHSSA--GSPIDLSGKLFSLLGTTVSRAAFGKENDDQDE 199 Query: 648 GLPSLPLARAM------DDVLETLFLRHVIPPACWRLMYRYGFGPEKKMAVARRIIDRFA 809 + + A M DD+ +L H++ + K+ + D+ Sbjct: 200 FMSLVRKAITMTGGFEVDDMFPSLKPLHLLTRQ------------KAKVEHVHQRADKIL 247 Query: 810 ADTIVKRRYSGHKLR-GEGI-TESSDILSFFICNDDASE----HSDEFLRDTAVNLLFAG 971 D + K +++ G G E D++ + ++ + E ++ N+ AG Sbjct: 248 EDILRKHMEKRTRVKEGNGSEAEQEDLVDVLLRLKESGSLEVPMTMENIKAVIWNIFAAG 307 Query: 972 RDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAALC 1151 DT+ + L W + +NP+V++ EL I K+ ++ ++L + YL + + Sbjct: 308 TDTSASTLEWAMSEMMKNPKVKEKAQAELRQIFKGKE-----IIRETDLEELSYLKSVIK 362 Query: 1152 ECLRLY-PSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPER 1328 E LRL+ PS I + ++ G+EI K+++ ++++GR W D F PER Sbjct: 363 ETLRLHPPSQLIPRECIISTNI--DGYEIPIKTKVMINTWAIGRDPQYW-SDADRFIPER 419 Query: 1329 WITDDGKLRHQ-PPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLETVPGHTVKP 1505 + +D + + +++I F AG R C G + A +L++F E + +KP Sbjct: 420 F--NDSSIDFKGNSFEYIPFGAGRRMCPGMTFGLASITLPLALLLYHFNWEL--PNKMKP 475 Query: 1506 KLSIVLHMKNGLAVTVKRRN 1565 + L M +TV R+N Sbjct: 476 E---DLDMDEHFGMTVARKN 492
>Q9FH66:C71AG_ARATH Cytochrome P450 71A16 - Arabidopsis thaliana (Mouse-ear cress)| Length = 497 Score = 79.3 bits (194), Expect = 5e-14 Identities = 52/180 (28%), Positives = 86/180 (47%), Gaps = 2/180 (1%) Frame = +3 Query: 978 TTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAALCEC 1157 TT AV+ W L NP + + DE+ ++ K++ V E+ +M YL A + E Sbjct: 303 TTSAVIEWAMTRLMRNPECLKKLQDEIRSVS---KMNSYV--SGKEVENMNYLKAVIKEV 357 Query: 1158 LRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWIT 1337 LRL+P +P+ DV G++I AG ++++ ++++ R WG D EF PER Sbjct: 358 LRLHPPLPLLVPRLLSEDVKLKGYDITAGTQVIINAWAIQRDTATWGSDAQEFRPERHFD 417 Query: 1338 DDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVL--WNFTLETVPGHTVKPKL 1511 + +K+I F AG R C G + A ++ +++ +E P KP L Sbjct: 418 STWDFVGR-NFKYIPFGAGRRLCPGIGLGSVMASVTLANLVKRFDWRVEDGPSGYDKPDL 476
>Q9VYY4:C4G15_DROME Cytochrome P450 4g15 - Drosophila melanogaster (Fruit fly)| Length = 574 Score = 79.3 bits (194), Expect = 5e-14 Identities = 58/215 (26%), Positives = 104/215 (48%), Gaps = 2/215 (0%) Frame = +3 Query: 924 SDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVL 1103 +D +++ ++F G DTT A S+F L+ + ++ +L EL I D Sbjct: 365 TDTEIKEQVDTIMFEGHDTTAAGSSFFLSLMGIHQDIQDRVLAELDSIFG----DSQRPA 420 Query: 1104 DASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSG-HEIKAGDKILVYSYSMGR 1280 + M YL L E LR+YP VP+ + + L SG + I G + V + + R Sbjct: 421 TFQDTLEMKYLERCLMETLRMYPPVPLIARELQEDLKLNSGNYVIPRGATVTVATVLLHR 480 Query: 1281 MEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVL 1460 V+ + F P+ ++ + RH Y F+ F+AGPR+C+G++ A ++K + +T+L Sbjct: 481 NPKVYANPNV-FDPDNFLPERQANRHY--YAFVPFSAGPRSCVGRKYAMLKLKILLSTIL 537 Query: 1461 WNFTL-ETVPGHTVKPKLSIVLHMKNGLAVTVKRR 1562 N+ + + K + I+L + G V ++ R Sbjct: 538 RNYRVYSDLTESDFKLQADIILKREEGFRVRLQPR 572 Score = 37.0 bits (84), Expect = 0.27 Identities = 23/95 (24%), Positives = 42/95 (44%) Frame = +3 Query: 153 PTEWPLLGHLLSTLANVSNLHDWATGVLATTRYNFAAHMGLTGVRFFLTCDPSNVRHIFI 332 P P++GHL + S++ + T + + + A M + DP +V + + Sbjct: 49 PRGLPIVGHLFDVIGPASSV--FRTVIRKSAPFEHIAKMWIGPKLVVFIYDPRDVE-LLL 105 Query: 333 SNSINYPRGEEYADIFDVLGDGIFNADGESWRRQR 437 S+ + + EY LGDG+ + G+ WR R Sbjct: 106 SSHVYIDKASEYKFFKPWLGDGLLISTGQKWRSHR 140
>Q29552:C11B1_PIG Cytochrome P450 11B1, mitochondrial precursor - Sus scrofa (Pig)| Length = 503 Score = 79.3 bits (194), Expect = 5e-14 Identities = 95/379 (25%), Positives = 159/379 (41%), Gaps = 10/379 (2%) Frame = +3 Query: 396 GIFNADGESWRRQRAKSQ----LIMASPRFRSFSARCTRDKVERSLLPFLAHAADVGARC 563 G+F +G +WR R + + A +F RD ++L + A Sbjct: 128 GVFLLNGPTWRLDRLQLNPGVLSLQAMQKFTPLVDGVARD-FSQALRARVMQNARGSLTL 186 Query: 564 DLHDVLLRLMFDMTCNLVFGVDPGCL--QIGLPSLPLARAMDDVLETLFLRHVIPPACWR 737 D+ + R + + ++FG G L Q SL A++ + ++ +P + R Sbjct: 187 DIKPSIFRYTIEASNLVLFGERLGLLAHQPNPESLDFIHALEVMFKSTVQLMFMPRSLSR 246 Query: 738 LMYRYGFGPEKKMAVARRIIDRFAADTIVKRRYS----GHKLRGEGITESSDILSFFICN 905 G K+ A I ++A + ++R Y GH G+ +++L+ Sbjct: 247 WT---STGTWKEHFEAWDCIFQYA-NKAIQRLYQELTLGHPWHYSGVV--AELLTHANMT 300 Query: 906 DDASEHSDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKV 1085 DA ++ +++L DTT L + L NP V+Q + E AAR Sbjct: 301 VDA-------IKANSIDLTAGSVDTTAYPLLMTLFELARNPEVQQALRQESLAAAARISE 353 Query: 1086 DDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYS 1265 + ++ + L AAL E LRLYP + T + VL + H I AG + V Sbjct: 354 NPQ-----KAITELPLLRAALKETLRLYPVGIFLDRCVTSDLVLQNYH-IPAGTLVKVLL 407 Query: 1266 YSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTV 1445 YS+GR V+ + + P+RW+ + G P +AF G R CLG+ +A +M + Sbjct: 408 YSLGRNPAVFARP-ERYHPQRWLDNQGSGTRFP---HLAFGFGMRQCLGRRLAQVEMLLL 463 Query: 1446 AATVLWNFTLETVPGHTVK 1502 VL NF +ET+ +K Sbjct: 464 LHHVLKNFLVETLVQEDIK 482
>P15150:C11B1_BOVIN Cytochrome P450 11B1, mitochondrial precursor - Bos taurus (Bovine)| Length = 503 Score = 79.3 bits (194), Expect = 5e-14 Identities = 96/388 (24%), Positives = 161/388 (41%), Gaps = 12/388 (3%) Frame = +3 Query: 396 GIFNADGESWRRQRAK-SQLIMASPRFRSFSARCTRDKVERSLLPFLAHAADVGAR---- 560 G+F +G WR R + + +++ P + ++ D V R L AR Sbjct: 128 GVFLLNGPQWRLDRLRLNPDVLSLPALQKYTPLV--DGVARDFSQTLKARVLQNARGSLT 185 Query: 561 CDLHDVLLRLMFDMTCNLVFGVDPGCL--QIGLPSLPLARAMDDVLETLFLRHVIPPACW 734 D+ + R + + +++G G L Q SL A++ +L++ +P Sbjct: 186 LDIAPSVFRYTIEASTLVLYGERLGLLTQQPNPDSLNFIHALEAMLKSTVQLMFVPRRLS 245 Query: 735 RLM----YRYGFGP-EKKMAVARRIIDRFAADTIVKRRYSGHKLRGEGITESSDILSFFI 899 R M +R F + A R I R + + GH GI +++L Sbjct: 246 RWMSTNMWREHFEAWDYIFQYANRAIQRIYQELAL-----GHPWHYSGIV--AELLM--- 295 Query: 900 CNDDASEHSDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARK 1079 ++ + + ++ ++L DTT L + L NP V+Q + E AR Sbjct: 296 ----RADMTLDTIKANTIDLTAGSVDTTAFPLLMTLFELARNPEVQQAVRQESLVAEARI 351 Query: 1080 KVDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILV 1259 + ++ + L AAL E LRLYP V IT + +D++ + I AG + V Sbjct: 352 SENPQ-----RAITELPLLRAALKETLRLYP-VGITLEREVSSDLVLQNYHIPAGTLVKV 405 Query: 1260 YSYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMK 1439 YS+GR V+ + + P+RW+ G P +AF G R CLG+ VA +M Sbjct: 406 LLYSLGRNPAVFARP-ESYHPQRWLDRQGSGSRFP---HLAFGFGVRQCLGRRVAEVEML 461 Query: 1440 TVAATVLWNFTLETVPGHTVKPKLSIVL 1523 + VL NF +ET+ +K +L Sbjct: 462 LLLHHVLKNFLVETLEQEDIKMVYRFIL 489
>O35084:CP27B_MOUSE 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial precursor -| Mus musculus (Mouse) Length = 507 Score = 79.0 bits (193), Expect = 6e-14 Identities = 94/387 (24%), Positives = 158/387 (40%), Gaps = 11/387 (2%) Frame = +3 Query: 396 GIFNADGESWRRQRAKSQLIMASPRFRSFSARCTRDKVERSLLPFLAHAADVGARC---- 563 G+ ADGE W+R R+ ++ P+ + A T D V R L+ L G+ Sbjct: 125 GLLTADGEEWQRLRSLLAPLLLRPQAAAGYAG-TLDNVVRDLVRRLRRQRGRGSGLPGLV 183 Query: 564 -DLHDVLLRLMFDMTCNLVFGVDPGCLQIGLPSLPLARAMDDVLETLFLRHVIPPACWRL 740 D+ + + ++ G GCL+ +P P + ++F+ ++ A Sbjct: 184 LDVAGEFYKFGLESIGAVLLGSRLGCLEAEVP--PDTETFIHAVGSVFVSTLLTMAMPNW 241 Query: 741 MYRYGFGPEKKMAVARRIIDRFA-ADTIVKRRYSGHKLRGEGITE----SSDILSFFICN 905 ++ GP ++ R FA A V+ R +R +G E S L+ F+ Sbjct: 242 LHHLIPGPWARLC--RDWDQMFAFAQRHVELREGEAAMRNQGKPEEDMPSGHHLTHFLFR 299 Query: 906 DDASEHSDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKV 1085 + S S + LL AG DT LSW Y L +P V+ + E+ Sbjct: 300 EKVSVQS---IVGNVTELLLAGVDTVSNTLSWTLYELSRHPDVQTALHSEITAGTRGSCA 356 Query: 1086 DDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYS 1265 + LS + L A + E LRLYP VP + D+ + I + + Sbjct: 357 HP----HGTALSQLPLLKAVIKEVLRLYPVVP-GNSRVPDRDIRVGNYVIPQDTLVSLCH 411 Query: 1266 YSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTV 1445 Y+ R + D F+P RW+ +G H P+ + F G R+C+G+ +A +++ Sbjct: 412 YATSR-DPTQFPDPNSFNPARWL-GEGPTPH--PFASLPFGFGKRSCIGRRLAELELQMA 467 Query: 1446 AATVLWNFTLETVPGH-TVKPKLSIVL 1523 + +L +F + PG +KP VL Sbjct: 468 LSQILTHFEVLPEPGALPIKPMTRTVL 494
>Q92087:CP19A_ORYLA Cytochrome P450 19A1 - Oryzias latipes (Medaka fish) (Japanese| ricefish) Length = 518 Score = 79.0 bits (193), Expect = 6e-14 Identities = 52/186 (27%), Positives = 91/186 (48%) Frame = +3 Query: 918 EHSDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMV 1097 E S E +R + ++ A DT L + LL +NP VE +L E+ I ++ + Sbjct: 299 ELSAENVRQCVLEMVIAAPDTLSISLFFMLLLLKQNPHVELQLLQEIDTIVGDSQLQNQ- 357 Query: 1098 VLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMG 1277 +L + L + + ECLR +P V T + A +D++ GH ++ G I++ + M Sbjct: 358 -----DLQKLQVLESFINECLRFHPVVDFTMRRALFDDII-DGHRVQKGTNIILNTGRMH 411 Query: 1278 RMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATV 1457 R E + EFS E + + + QP F +GPR C+G+ +A MK++ T+ Sbjct: 412 RTE--FFHKANEFSLENFQKNTPRRYFQP------FGSGPRACVGRHIAMVMMKSILVTL 463 Query: 1458 LWNFTL 1475 L +++ Sbjct: 464 LSQYSV 469
>O46515:CP11A_HORSE Cytochrome P450 11A1, mitochondrial precursor - Equus caballus| (Horse) Length = 520 Score = 79.0 bits (193), Expect = 6e-14 Identities = 84/337 (24%), Positives = 148/337 (43%), Gaps = 13/337 (3%) Frame = +3 Query: 579 LLRLMFDMTCNLVFGVDPGCLQIGLPSLPLARAMDDVLETLFLRHV----IPPACWRLMY 746 L R F+ N++FG G L + P A+ D + +F V +PP +RL Sbjct: 202 LFRFAFESITNVIFGERQGMLDEIVD--PEAQRFIDAVYKMFHTSVPMLSLPPDLFRLFR 259 Query: 747 RYGFGP-----EKKMAVARRIIDRFAADTIVKRRYSGHKLRGEGITE---SSDILSFFIC 902 + + + A + ++F D KR + + GI +S+ L F Sbjct: 260 TKTWRDHVAAWDTVFSKAEQYTEKFYQDLKQKRHFDSYP----GIFYRLLASNKLPF--- 312 Query: 903 NDDASEHSDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKK 1082 + ++ +L G DTT L W Y + N RV++M+ +E+ +AAR++ Sbjct: 313 ---------KDIQANVTEMLAGGVDTTSMSLQWHLYEIARNLRVQEMLREEV--LAARRQ 361 Query: 1083 VDDMVVLDASELSSMV-YLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILV 1259 D S + MV L A++ E LRL+P + +T + ND++ + I A + V Sbjct: 362 AQG----DTSTMVQMVPLLKASIKETLRLHP-IAVTLQRYPQNDLVIRDYMIPAKTLVQV 416 Query: 1260 YSYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMK 1439 Y+MG+ + + + F P RW+ + L H ++ + F G R CLG+ +A +M Sbjct: 417 SIYTMGQ-DPTFFSNPRRFDPTRWLDKNKDLTH---FRNLGFGWGVRQCLGRRIAELEMT 472 Query: 1440 TVAATVLWNFTLETVPGHTVKPKLSIVLHMKNGLAVT 1550 +L NF +E + V ++L + ++ T Sbjct: 473 LFLIHILENFRVEIQHLNDVDSTFGLILIPEKPISFT 509
>Q42798:C93A1_SOYBN Cytochrome P450 93A1 - Glycine max (Soybean)| Length = 509 Score = 79.0 bits (193), Expect = 6e-14 Identities = 74/275 (26%), Positives = 131/275 (47%), Gaps = 17/275 (6%) Frame = +3 Query: 798 DRF--AADTIVKRRYSGHKLRGEGITESS-----DILSFFICNDDASEHSDEF-LRDTAV 953 DRF D I+K+R + E T D+L +++A D+ ++ + Sbjct: 242 DRFDVVVDGIIKQRQEERRKNKETGTAKQFKDMLDVLLDMHEDENAEIKLDKKNIKAFIM 301 Query: 954 NLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVY 1133 ++ AG DT+ + W L NP V + E+ + + ++ ++ S+++++ Y Sbjct: 302 DIFVAGTDTSAVSIEWAMAELINNPDVLEKARQEIDAVVGKSRM-----VEESDIANLPY 356 Query: 1134 LHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCME 1313 L A + E LRL+P P+ + ++ + V+ G++I A ++ V +++GR W K E Sbjct: 357 LQAIVRETLRLHPGGPLVVRESSKSAVV-CGYDIPAKTRLFVNVWAIGRDPNHWEKP-FE 414 Query: 1314 FSPERWITD-----DGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLE 1478 F PER+I D D + +H Y FI F +G RTC G +A+ + A ++ F + Sbjct: 415 FRPERFIRDGQNQLDVRGQH---YHFIPFGSGRRTCPGASLAWQVVPVNLAIIIQCFQWK 471 Query: 1479 TVPGH---TVKPKLSIVLHMKNG-LAVTVKRRNFF 1571 V G+ ++ K I L N + V V R N F Sbjct: 472 LVGGNGKVDMEEKSGITLPRANPIICVPVPRINPF 506
>P37123:C77A1_SOLME Cytochrome P450 77A1 - Solanum melongena (Eggplant) (Aubergine)| Length = 499 Score = 79.0 bits (193), Expect = 6e-14 Identities = 56/206 (27%), Positives = 90/206 (43%), Gaps = 5/206 (2%) Frame = +3 Query: 960 LFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLH 1139 L G DTT L W L ENP ++ + E+ I KKVD+ +++ M YL+ Sbjct: 300 LNGGTDTTATALEWGIGRLMENPTIQNQLYQEIKTIVGDKKVDE------NDIEKMPYLN 353 Query: 1140 AALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFS 1319 A + E LR +P T + V +G++I + + + + VW D +F Sbjct: 354 AVVKELLRKHPPTYFTLTHSVTEPVKLAGYDIPMDTNVEFFVHGISHDPNVW-SDPEKFD 412 Query: 1320 PERWIT--DDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLETVPGH 1493 P+R+++ +D + K + F G R C G +A + + A ++ F PG+ Sbjct: 413 PDRFLSGREDADITGVKEVKMMPFGVGRRICPGLGMATVHVNLMLARMVQEFEWFAYPGN 472 Query: 1494 T---VKPKLSIVLHMKNGLAVTVKRR 1562 KL + MKN L VK R Sbjct: 473 NKVDFSEKLEFTVVMKNPLRAKVKLR 498
>Q4G0S4:C27C1_HUMAN Cytochrome P450 27C1 - Homo sapiens (Human)| Length = 372 Score = 79.0 bits (193), Expect = 6e-14 Identities = 51/175 (29%), Positives = 89/175 (50%) Frame = +3 Query: 957 LLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYL 1136 +L AG DTT LSW Y+L +P V+Q + E+ K + + V A+++ + + Sbjct: 177 MLLAGVDTTSFTLSWTVYILARHPEVQQTVYREIV-----KNLGERHVPTAADVPKVPLV 231 Query: 1137 HAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEF 1316 A L E LRL+P +P + T D++ G+ I G ++ + Y+ + + + EF Sbjct: 232 RALLKETLRLFPVLP-GNGRVTQEDLVIGGYLIPKGTQLALCHYATSYQDENFPR-AKEF 289 Query: 1317 SPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLET 1481 PERW+ G L + I F G R+C+G+ +A ++ V +L +F ++T Sbjct: 290 RPERWLR-KGDLDRVDNFGSIPFGHGVRSCIGRRIAELEIHLVVIQLLQHFEIKT 343
>P51663:C11B1_SHEEP Cytochrome P450 11B1, mitochondrial precursor - Ovis aries (Sheep)| Length = 503 Score = 79.0 bits (193), Expect = 6e-14 Identities = 60/196 (30%), Positives = 92/196 (46%) Frame = +3 Query: 936 LRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASE 1115 ++ ++L DTT L + L NP V+Q + E + A ++ + +E Sbjct: 304 IKANTIDLTAGSVDTTAFPLLMTLFELARNPEVQQALRQE--SLVAEARISENPQRATTE 361 Query: 1116 LSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVW 1295 L L AAL E LRLYP V IT + +D++ + I AG + V YS+GR V+ Sbjct: 362 LP---LLRAALKETLRLYP-VGITLERQVSSDLVLQNYHIPAGTLVKVLLYSLGRNPAVF 417 Query: 1296 GKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTL 1475 + + P+RW+ G P +AF G R CLG+ VA +M + VL NF + Sbjct: 418 ARP-ESYHPQRWLDRQGSGSRFP---HLAFGFGMRQCLGRRVAEVEMLLLLHHVLKNFLV 473 Query: 1476 ETVPGHTVKPKLSIVL 1523 ET+ +K +L Sbjct: 474 ETLAQEDIKMVYRFIL 489
>Q29496:CP3AO_SHEEP Cytochrome P450 3A24 - Ovis aries (Sheep)| Length = 503 Score = 78.6 bits (192), Expect = 8e-14 Identities = 110/491 (22%), Positives = 190/491 (38%), Gaps = 18/491 (3%) Frame = +3 Query: 60 SMEHWYWF-VGLVCCFL-SYYRRLQSKKTTKEEPTEWPLLGHLLSTLANVSNLHDWATGV 233 S+E W + LV +L Y KK P P G++LS + GV Sbjct: 8 SLETWVLLAISLVLLYLYGTYSHGLFKKLGVSGPRPLPYFGNVLS----------YRKGV 57 Query: 234 LATTRYNFAAHMGLTGV-----RFFLTCDPSNVRHIFISNSINYPRGEEYADIFDVLGDG 398 F + + GV + DP ++ + + + ++ + Sbjct: 58 CEFDEECFKKYGKMWGVFEGKQPLLVITDPDVIKTVLVKECYSVFTNRRVFGPMGIMKNA 117 Query: 399 IFNADGESWRRQRAKSQLIMASPRFRSFSARCTRDKVERS---LLPFLAHAADVGARCDL 569 + A+ E W+R R + SP F S + + + L+ L A+ G ++ Sbjct: 118 VSVAEDEQWKRIRT-----LLSPTFTSGKLKDMFPIIGKYGDVLVRNLRKEAEKGKSVNM 172 Query: 570 HDVLLRLMFDMTCNLVFGVDPGCLQIGLPSLPLARAMDDVLETLFLRHVIPPACWRLMYR 749 D+ D+ + FGV+ L G P P +L +++ P ++ Sbjct: 173 KDIFGAYSMDVITSTSFGVNIDSL--GNPQDPFVENAKKLLRF----NILDPFLLSVVL- 225 Query: 750 YGFGPEKKMAVARRIIDRFAADTIVK--RRYSGHKLRGEGITESSDILSFFICNDDASEH 923 + F + + + A D + K +R +L+ + D L I + ++ E Sbjct: 226 FPFLVPIFEVLNITMFPKSAVDFLTKSVKRIKESRLK-DNQKPRVDFLQLMINSQNSKET 284 Query: 924 ------SDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKV 1085 SD+ L +V +FAG +TT LS+ Y+L +P V+Q + +E+ K Sbjct: 285 DNHKALSDQELMAQSVIFIFAGYETTSNTLSFLLYILATHPDVQQKLQEEIDATFPNKAP 344 Query: 1086 DDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYS 1265 V L+ M YL + E LR++P + + DV G I G + V Sbjct: 345 PTYDV-----LAQMEYLDMVVNETLRMFP-IAVRLDRLCKKDVEIHGVSIPKGTAVTVPI 398 Query: 1266 YSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTV 1445 + + R +W + EF PER+ + + PY ++ F GPR C+G A MK Sbjct: 399 FVLHRDPQLW-PEPEEFRPERFSKKNKDSIN--PYVYLPFGTGPRNCIGMRFAIMNMKLA 455 Query: 1446 AATVLWNFTLE 1478 VL NF+ + Sbjct: 456 IVRVLQNFSFK 466
>Q9VWR2:CP308_DROME Probable cytochrome P450 308a1 - Drosophila melanogaster (Fruit fly)| Length = 490 Score = 78.6 bits (192), Expect = 8e-14 Identities = 123/502 (24%), Positives = 198/502 (39%), Gaps = 30/502 (5%) Frame = +3 Query: 147 EEPTEWPLLGHLLSTLANVSNLHDWATGVLATTRYN---FAAHMGLTGVRFF-------- 293 E P WPL+G++L D+A G + + + GL V F+ Sbjct: 30 EAPFGWPLVGNML----------DFALGRRSYGEIYQEIYTRNPGLKYVGFYRLFNEPAI 79 Query: 294 LTCDPSNVRHIFIS-NSINYPRGEEYADIF-DVLGD-GIFNADGESWRRQRAKSQLIMAS 464 L D +R I + N + Y D DVL F A+G+ WR RA Sbjct: 80 LVRDQELLRQILVGRNFADCADNAVYVDHQRDVLASHNPFIANGDRWRVLRAD-----LV 134 Query: 465 PRFRSFSARCTRDKVERSLLPFLAHAADVGARCDLHDVLLRLMFDMTCNLVFGVDPGCLQ 644 P F R T V R+ L +G R + D+ R + + +FG+D CL Sbjct: 135 PLFTPSRVRQTLPHVARAC-QLLRDQVPLG-RFEAKDLATRYTLQVVASAIFGLDAHCLG 192 Query: 645 IGLPSLPLARAMDDVLETLFLRHVIPPACWRLMYRYGF--GPEKKMAVARRIID---RFA 809 I + +A LE +L + P+ W L+ P + R + + Sbjct: 193 I---HMRVAHEPSRWLE--WLAPLFQPSVWSLLETMSLLHTPRLGRLIGHRYVPLPLQHW 247 Query: 810 ADTIVKRRYSGHKLRGEGITESSDILSFFICNDDASEHSDEFLRDTAVNLLFAGRDTTGA 989 +V+ R G L + + ES L E L A LL G +T+ Sbjct: 248 FRELVEARSGGDNLL-QWLAESKRGLG------------KEELAGHATTLLLEGYETSAM 294 Query: 990 VLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAALCECLRLY 1169 +L++ Y L N ++ + EL +A R + ++D L + Y AAL E LRL+ Sbjct: 295 LLAFALYELALNEDAQRRLHIELDEVAQRHAGN---LIDPVALGELRYSEAALLEALRLH 351 Query: 1170 PSVPITHKAATHNDVLP-----SGHEIKAG-DKILVYSYSMGRMEGVWGKDCMEFSPERW 1331 P++ K T LP + E+K +LV ++ +F PER+ Sbjct: 352 PAMQALQKRCTKTFTLPDQKSGASSELKVHLGTVLVLPVQAIHLDPALYPAPNQFRPERF 411 Query: 1332 ITDDGKLRHQPPY--KFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLETVPGHTVKP 1505 + +QPP +F+ F AGPR C G + Q K T+L + ++ + Sbjct: 412 L-------NQPPMGCRFLGFGAGPRMCPGMRLGLLQTKAALTTLLQDHCVQLADEDQCRV 464 Query: 1506 KLSIVLHM---KNGLAVTVKRR 1562 ++S + + +NG+ ++ KRR Sbjct: 465 EVSPLTFLTASRNGIWLSFKRR 486
>Q91W64:CP270_MOUSE Cytochrome P450 2C70 - Mus musculus (Mouse)| Length = 489 Score = 78.6 bits (192), Expect = 8e-14 Identities = 112/501 (22%), Positives = 213/501 (42%), Gaps = 25/501 (4%) Frame = +3 Query: 81 FVGL-VCCFLSYYRRLQSKKTTK--EEPTEWPLLGHLLSTLANVSNLHDWATGVLATTRY 251 F+G+ + CFL + Q + K PT P++G++L +V N+ + G+LA +Y Sbjct: 6 FLGIWLSCFLFLFLWNQHRGRGKLPPGPTPLPIVGNILQV--DVKNISK-SMGMLAK-KY 61 Query: 252 N--FAAHMGLTGVRFFLTCDPSNVRHIFIS-NSINYPRGEEYADIFDVL-------GDGI 401 F ++G+ P+ V H + + +G+E++D D G GI Sbjct: 62 GPVFTVYLGMK---------PTVVLHGYKAMKEALIDQGDEFSDKTDSSLLSRTSQGLGI 112 Query: 402 FNADGESWRRQRAKSQLIMASPRFRSFSARCTRDKVERSLLPFL-AHAADVGARCDLHDV 578 ++GE+W++ R S +++ S + D+++ +L L A G+ CD + Sbjct: 113 VFSNGETWKQTRRFSLMVLRS---MGMGKKTIEDRIQEEILYMLDALRKTNGSPCDPSFL 169 Query: 579 LLRLMFDMTCNLVFGVDPGCLQIGLPSLPLARAMDDVLETLFLRHVIPPACW-RLMYRYG 755 L + ++ ++F + D +E + I + W +L Y Sbjct: 170 LACVPCNVISTVIFQHRFDYND---------QTFQDFMENFHRKIEILASPWSQLCSAYP 220 Query: 756 FGPEKKMAVARRIIDRFAADTIVKRRYSGHKL----RGEGITESSDILSFFICNDDASEH 923 + I +RF D ++++ ++ + ++ D + +F+ + +H Sbjct: 221 I-----LYYLPGIHNRFLKDVTQQKKFILEEINRHQKSLDLSNPQDFIDYFLIKMEKEKH 275 Query: 924 SD--EFLRDTAV----NLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKV 1085 + EF D V +L AG +TT + + + LL + P V I +E+A + R + Sbjct: 276 NQKSEFTMDNLVVSIGDLFGAGTETTSSTVKYGLLLLLKYPEVTAKIQEEIAHVIGRHRR 335 Query: 1086 DDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYS 1265 M + + M Y A L E R VPI T DV G+ I G ++ Sbjct: 336 PTM-----QDRNHMPYTDAVLHEIQRYIDFVPIPSPRKTTQDVEFRGYHIPKGTSVMACL 390 Query: 1266 YSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTV 1445 S+ + + +F P ++ + G + F+AF+AG R C+G+ +A +M + Sbjct: 391 TSVLNDDKEFPNP-EKFDPGHFLDEKGNFKKSD--YFVAFSAGRRACIGEGLARMEMFLI 447 Query: 1446 AATVLWNFTLETVPGHTVKPK 1508 +L +FTL+ + VKP+ Sbjct: 448 LTNILQHFTLKPL----VKPE 464
>Q95M61:CP19A_CALJA Cytochrome P450 19A1 - Callithrix jacchus (Common marmoset)| Length = 503 Score = 78.6 bits (192), Expect = 8e-14 Identities = 89/373 (23%), Positives = 158/373 (42%), Gaps = 5/373 (1%) Frame = +3 Query: 399 IFNADGESWRRQRAKSQLIMASPRFRSFSARCTRDKVERSLLPFLAHAADVGARCDLHDV 578 IFN + + W+ R ++ P C SL L +V DV Sbjct: 133 IFNNNPDLWKTTRPLFMKALSGPGLVRMVTVCAE-----SLNTHLDRLEEVTNESGFIDV 187 Query: 579 L--LRLMFDMTCNLVFGVDPGCLQIGLPSLPLARAMDDVLETLFLRHVIPPACWRLMYRY 752 L LR + T N +F L+I L + + + + P +++ + Y Sbjct: 188 LTLLRCVMLDTSNTLF------LRIPLDENAIVFKIQGYFDAWQALLIKPDIFFKISWLY 241 Query: 753 GFGPEKKMAVARRIIDRFAADTIVKRRYSGHKLRGEGITESSDILSFFICNDDASEHSDE 932 EK + + I+ A+ +RR S E + E D + I + + + E Sbjct: 242 K-KYEKSVKDLKDAIEVLMAEK--RRRISAE----EKLEEHIDFATELILAEKRGDLTRE 294 Query: 933 FLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARK--KVDDMVVLD 1106 + + +L A DT L + +L+ ++P VE+ I+ E+ + + K+DD+ L Sbjct: 295 NVNQCMLEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIMKEIQTVVGERDVKIDDIQKLK 354 Query: 1107 ASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRME 1286 E + +Y E +R P V + + A +DV+ G+ +K G I++ ++GRM Sbjct: 355 VVE--NFIY------ESMRYQPVVDLVMRKALEDDVI-DGYPVKKGTNIIL---NIGRMH 402 Query: 1287 GVWGKDCMEFSPE-RWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLW 1463 +EF P+ T + ++ P F F GPR+C GK +A MK++ T+L Sbjct: 403 R------LEFFPKPNEFTLENFAKNVPYRYFQPFGFGPRSCAGKYIAMVMMKSILVTLLR 456 Query: 1464 NFTLETVPGHTVK 1502 F ++T+ G V+ Sbjct: 457 RFHVKTLGGECVE 469
>Q9VFJ0:CP131_DROME Probable cytochrome P450 313a1 - Drosophila melanogaster (Fruit fly)| Length = 492 Score = 78.6 bits (192), Expect = 8e-14 Identities = 108/475 (22%), Positives = 186/475 (39%), Gaps = 15/475 (3%) Frame = +3 Query: 102 FLSYYRRLQSKKTTKEEPTEWPLLGHLLSTLANVSNLHDWATGVLATTRYNFAAHMGLTG 281 FL RRL P P+LG L + + T L +Y + Sbjct: 18 FLWSRRRLYFLMLKIPGPIGLPILGSSLENIITYKRKLSFRTKYL--NKYGSTILTWMGP 75 Query: 282 VRFFLTCDPSNVRHIFISNSINYPRGEEYADIFDVLGDGIFNADGESWRRQRA------K 443 V F +T DP V IF S + I +G+G+ W +R K Sbjct: 76 VPFIVTRDPKVVEDIFSSPDCHNKSQHIVNAITSCMGNGLLGKQDPHWLDRRKHFNPSFK 135 Query: 444 SQLIMASPRFRSFSARCTRDKVERSLLPFLAHAADVGARCDLHDVLLRLMFDMTCNLVFG 623 L+++ F F A KV +LL ++ D+ +LR F + G Sbjct: 136 QDLLLSF--FHIFDAET---KVLMNLLDTYVDKGEI----DVVPEMLRWSFKIAAQTTMG 186 Query: 624 VDP--------GCLQIGLPSLPLARAMDDVLETLFLRHVIPPACWRLMYRYGFGPEKKMA 779 + G L SL ++ + ++L L +I C G +K A Sbjct: 187 SEVKHDEHFKNGSLVESFESL-ISHSTLNILMPLVQNRMISKIC---------GYDKLRA 236 Query: 780 VARRIIDRFAADTIVKRRYSGHKLRGEGITESSDILSFFICNDDASEHSDEFLRDTAVNL 959 I + D +V ++ + + + ES+ +++ + + + ++ + Sbjct: 237 DNFSRIQKML-DNVVNKKVNPLP-KTDSDPESNIVINRAMELYRKGDITYMDVKSECCIM 294 Query: 960 LFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLH 1139 + AG DT+ + +LL +P ++ + +EL + + D +L YL Sbjct: 295 IAAGYDTSALTVYHALFLLANHPEHQEAVFEELNGVFPDAGHFGITYPDMQKLD---YLE 351 Query: 1140 AALCECLRLYPSVPITHKAATHNDV-LPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEF 1316 + E LRL P++PIT + T NDV L +G I G I + + R VWG D F Sbjct: 352 RVIKETLRLIPAIPITAR-ETKNDVRLSNGVLIPKGVVIGIDMFHTHRNPEVWGPDADNF 410 Query: 1317 SPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLET 1481 +P+ ++ ++ + +H PY +I F G R C+G + A K +L N+ + T Sbjct: 411 NPDNFLAENMEQKH--PYAYIPFARGKRNCIGSKYAMMSSKFALCRILRNYKIST 463
>O04790:C75A7_EUSGR Flavonoid 3',5'-hydroxylase - Eustoma grandiflorum (Bluebells)| (Lisianthus russellianus) Length = 510 Score = 78.6 bits (192), Expect = 8e-14 Identities = 59/227 (25%), Positives = 105/227 (46%), Gaps = 5/227 (2%) Frame = +3 Query: 813 DTIVKRRYSGHKLRGEGITESSDILSFFICNDDASEHS---DEFLRDTAVNLLFAGRDTT 983 D ++ R H S D L F + N D SE ++ +N+ AG DT+ Sbjct: 251 DALLTRLLEEHTASAHERKGSPDFLDFVVANGDNSEGERLQTVNIKALLLNMFTAGTDTS 310 Query: 984 GAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAALCECLR 1163 +V+ W L +NP + + +E+ + R D L+A ++S + YL A E R Sbjct: 311 SSVIEWALAELLKNPIILRRAQEEMDGVIGR----DRRFLEA-DISKLPYLQAICKEAFR 365 Query: 1164 LYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWI-TD 1340 +PS P+ +GH I G ++ V +++GR VW ++ EF+P+R++ Sbjct: 366 KHPSTPLNLPRIASQACEVNGHYIPKGTRLSVNIWAIGRDPSVW-ENPNEFNPDRFLERK 424 Query: 1341 DGKLRHQ-PPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLE 1478 + K+ + ++ I F AG R C G + ++ + T++ +F E Sbjct: 425 NAKIDPRGNDFELIPFGAGRRICAGTRLGILLVEYILGTLVHSFVWE 471
>P93531:C71D7_SOLCH Cytochrome P450 71D7 - Solanum chacoense (Chaco potato)| Length = 500 Score = 78.6 bits (192), Expect = 8e-14 Identities = 102/496 (20%), Positives = 204/496 (41%), Gaps = 18/496 (3%) Frame = +3 Query: 75 YWFVGLVCCFLSYYRRLQSKKTTKEEPTEW--PLLG---HLLSTLANVSNLHDWATGVLA 239 + F+ + + + L + +T K P W P +G HL L + L D A Sbjct: 7 FLFISFLFLLRKWKKYLNNSQTKKLPPGPWKLPFIGGMHHLAGGLPH-RVLRDLAE---- 61 Query: 240 TTRYNFAAHMGLTGVRFFLTCDPSNVRHIFISNSINYPRGEEYADIFDVL----GDGIFN 407 +Y H+ L V + P + + ++ I + + + D++ D F+ Sbjct: 62 --KYGPLMHLQLGEVSAVVVTSPEMAKQVLKTHDIAFASRPKLLAM-DIICYNRRDIAFS 118 Query: 408 ADGESWRRQRAKSQL-IMASPRFRSFSARCTRDKVERSLLPFLAHAADVGARCDLHDVLL 584 G+ WR+ R + ++++ RSFS+ D+V R L+ + G + + ++ Sbjct: 119 PYGDYWRQMRKICIMEVLSAKSVRSFSS-IRHDEVVR-LIDSIQPCFTSGELVNFTERII 176 Query: 585 RLMFDMTCNLVFGVDPGCLQIGLPSLPLARAMDDVLETLFLRHVIPPACWRLMYRYGFGP 764 MTC FG L+ + L R + + E + + P ++ ++ +G G Sbjct: 177 WFTSSMTCRSAFGQ---VLKEQEVFIKLIREVISLAEGFDVADIFPS--YKFLHGFG-GA 230 Query: 765 EKKMAVARRIIDRFAADTIVKRRYSGHKLRGEGITESSDILSFFI--CNDDASEH--SDE 932 ++K+ A R +D D I + + + + + D++ + ND + + +++ Sbjct: 231 KQKLLNAHRKVDSIVEDVIKEHKKNLATRKSDDAIGGEDLVDALVRLMNDKSLQFPINND 290 Query: 933 FLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDAS 1112 ++ ++L AG +T+ W + +NP V A R+ D V D + Sbjct: 291 NIKAVIIDLFAAGTETSSTTTVWAMAEMLKNPSVFAK-----AQAKVREAFRDKVTFDEN 345 Query: 1113 ELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGV 1292 ++ + YL + E +RL+ VP+ + +G+ I K++V +++GR Sbjct: 346 DVEELKYLKLVIKETMRLHAPVPLLVPRECREETEINGYTIPVKTKVMVNVWALGRDPKY 405 Query: 1293 WGKDCMEFSPERW----ITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVL 1460 W D F PER+ I G ++++ F G R C G + A +L Sbjct: 406 W-DDAESFKPERFEQCSIDFIGN-----NFEYLPFGGGRRICPGISFGLANVYLPLAQLL 459 Query: 1461 WNFTLETVPGHTVKPK 1508 ++F + G ++PK Sbjct: 460 YHFDWKLPTG--MEPK 473
>Q64464:CP3AD_MOUSE Cytochrome P450 3A13 - Mus musculus (Mouse)| Length = 503 Score = 78.2 bits (191), Expect = 1e-13 Identities = 63/216 (29%), Positives = 100/216 (46%), Gaps = 2/216 (0%) Frame = +3 Query: 924 SDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVL 1103 SD + +V +FAG +TT + LS+ YLL +P V++ + DE+ K Sbjct: 291 SDVEIVAQSVIFIFAGYETTSSALSFALYLLAIHPDVQKKLQDEIDAALPNK-----APA 345 Query: 1104 DASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRM 1283 L M YL + E LRLYP + DV +G I G +++ ++++ + Sbjct: 346 TYDTLLQMEYLDMVVNETLRLYPIAGRLERVCK-TDVEINGLFIPKGTVVMIPTFALHKD 404 Query: 1284 EGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLW 1463 W + EF PER+ + + PY ++ F +GPR C+G A MK VL Sbjct: 405 PKYWPEP-EEFRPERFSKKNQDSIN--PYMYLPFGSGPRNCIGMRFALINMKVALVRVLQ 461 Query: 1464 NFTLETVPGHTVKPKLSI--VLHMKNGLAVTVKRRN 1565 NFT++ + KLS +L +N L + V R+ Sbjct: 462 NFTVQPCKETEIPLKLSKQGLLQPENPLLLKVVSRD 497
>P51538:CP3A9_RAT Cytochrome P450 3A9 - Rattus norvegicus (Rat)| Length = 503 Score = 78.2 bits (191), Expect = 1e-13 Identities = 99/421 (23%), Positives = 166/421 (39%), Gaps = 17/421 (4%) Frame = +3 Query: 303 DPSNVRHIFISNSINYPRGEEYADIFDVLGDGIFNADGESWRRQRAKSQLIMASPRFRSF 482 DP ++ + + + +L I ++ E W+R RA + SP F S Sbjct: 86 DPDIIKTVLVKECYSTFTNRRNFGPVGILKKAISISEDEEWKRIRA-----LLSPTFTSG 140 Query: 483 SARCTRDKVER---SLLPFLAHAADVGARCDLHDVLLRLMFDMTCNLVFGVDPGCLQIGL 653 + + + L+ + ++ G + D+ D+ FGV+ L Sbjct: 141 KLKEMFPIINQYTDMLVRNMRQGSEEGKPTSMKDIFGAYSMDVITATSFGVNVDSLNN-- 198 Query: 654 PSLPLARAMD-----DVLETLFLRHVIPPACWRLMYRYGFGPEKKMAVARRIIDRFAADT 818 P P + D+ + LFL + P L F R +ID F T Sbjct: 199 PQDPFVEKVKKLLKFDIFDPLFLSVTLFPFLTPL-----FEALNVSMFPRDVIDFFK--T 251 Query: 819 IVKRRYSGHKLRGEGITESSDILSFFICNDDAS-EHSDEFLRDT-----AVNLLFAGRDT 980 V+R E + D L I + ++ + S + L D +V +FAG +T Sbjct: 252 SVERMKENRMKEKE--KQRMDFLQLMINSQNSKVKDSHKALSDVEIVAQSVIFIFAGYET 309 Query: 981 TGAVLSWFFYLLCENPRVEQMILDEL---APIAARKKVDDMVVLDASELSSMVYLHAALC 1151 T + LS+ YLL +P +++ + DE+ P A D ++ M YL + Sbjct: 310 TSSALSFVLYLLAIHPDIQKKLQDEIDAALPNKAHATYDTLL--------QMEYLDMVVN 361 Query: 1152 ECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERW 1331 E LRLYP + DV +G I G +++ ++++ + W + EF PER+ Sbjct: 362 ETLRLYPIAGRLERVCK-TDVEINGVFIPKGTVVMIPTFALHKDPHYWPEP-EEFRPERF 419 Query: 1332 ITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLETVPGHTVKPKL 1511 + + PY ++ F GPR C+G A MK VL NF+ + + KL Sbjct: 420 SKKNQD--NINPYMYLPFGNGPRNCIGMRFALMNMKVALFRVLQNFSFQPCKETQIPLKL 477 Query: 1512 S 1514 S Sbjct: 478 S 478
>Q02318:CP27A_HUMAN Cytochrome P450 27, mitochondrial precursor - Homo sapiens (Human)| Length = 531 Score = 78.2 bits (191), Expect = 1e-13 Identities = 89/391 (22%), Positives = 158/391 (40%), Gaps = 15/391 (3%) Frame = +3 Query: 360 EEYADIFDVLGDGIFNADGESWRRQRAKSQLIMASPRFRSFSARCTRDKVE---RSLLPF 530 +E+ D D L G F +G W + R + P + + ++ L Sbjct: 134 KEHRDQHD-LTYGPFTTEGHHWYQLRQALNQRLLKPAEAALYTDAFNEVIDDFMTRLDQL 192 Query: 531 LAHAADVGARCDLHDVLLRLMFDMTCNLVFGVDPGCLQIGLP--SLPLARAM----DDVL 692 A +A D+ + + C ++F GCLQ +P ++ R++ + L Sbjct: 193 RAESASGNQVSDMAQLFYYFALEAICYILFEKRIGCLQRSIPEDTVTFVRSIGLMFQNSL 252 Query: 693 ETLFL----RHVIPPACWRLMYRYGFGPEKKMAVARRIIDRFAADTIVKRRYSGHKLRGE 860 FL R V+P W+ RY G + +++ID D + + +G + Sbjct: 253 YATFLPKWTRPVLP--FWK---RYLDGWNAIFSFGKKLIDEKLEDMEAQLQAAGP----D 303 Query: 861 GITESSDILSFFICNDDASEHSDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQ 1040 GI + S L F + + S + LL AG DTT L+W Y L ++P +++ Sbjct: 304 GI-QVSGYLHFLLASGQLSPRE---AMGSLPELLMAGVDTTSNTLTWALYHLSKDPEIQE 359 Query: 1041 MILDELAPIAARKKVDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLP 1220 + +E+ + +V + + M L A L E LRLYP VP T+ ++ Sbjct: 360 ALHEEVVGVVPAGQVP-----QHKDFAHMPLLKAVLKETLRLYPVVP-TNSRIIEKEIEV 413 Query: 1221 SGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWI--TDDGKLRHQPPYKFIAFNAG 1394 G + + Y + R + + F P RW+ + R Q P+ + F G Sbjct: 414 DGFLFPKNTQFVFCHYVVSRDPTAFSEP-ESFQPHRWLRNSQPATPRIQHPFGSVPFGYG 472 Query: 1395 PRTCLGKEVAFTQMKTVAATVLWNFTLETVP 1487 R CLG+ +A +M+ + A ++ + + P Sbjct: 473 VRACLGRRIAELEMQLLLARLIQKYKVVLAP 503
>P58045:C71AE_ARATH Cytochrome P450 71A14 - Arabidopsis thaliana (Mouse-ear cress)| Length = 497 Score = 78.2 bits (191), Expect = 1e-13 Identities = 47/173 (27%), Positives = 85/173 (49%) Frame = +3 Query: 951 VNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMV 1130 +++ AG +TT A+L W L +P + + DE+ A + ++ + ++ M Sbjct: 294 LDMFLAGTETTYALLEWIMTELIRHPECMKKLQDEIRAKATKL----ILYISEEDVEDMK 349 Query: 1131 YLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCM 1310 YL A + E LRL+P +P+ D+ G++I AG ++++ ++++ R WG D Sbjct: 350 YLKAVVKEVLRLHPPLPLLVPRELSEDIKLKGYDIAAGTQVIINAWAIQRDTMTWGIDAE 409 Query: 1311 EFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNF 1469 EF PER + R ++FI F +G R C G A ++ A ++ F Sbjct: 410 EFRPERHLDSLVDFR-GTNFEFIPFGSGRRICPGIGFAMALVEVTLANLVNRF 461
>P15393:C11B1_RAT Cytochrome P450 11B1, mitochondrial precursor - Rattus norvegicus| (Rat) Length = 499 Score = 78.2 bits (191), Expect = 1e-13 Identities = 59/209 (28%), Positives = 99/209 (47%) Frame = +3 Query: 858 EGITESSDILSFFICNDDASEHSDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVE 1037 EG +S ++S + S S + + ++ L+ DTT L + L NP V+ Sbjct: 280 EGRQQSWSVISEMVAQ---STLSMDAIHANSMELIAGSVDTTAISLVMTLFELARNPDVQ 336 Query: 1038 QMILDELAPIAARKKVDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVL 1217 Q + E +AA + V +S + L AAL E LRLYP + H+D++ Sbjct: 337 QALRQE--SLAAEASI---VANPQKAMSDLPLLRAALKETLRLYPVGSFVERIV-HSDLV 390 Query: 1218 PSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGP 1397 + + AG +++Y YSMGR V+ + + P+RW L + ++ +AF G Sbjct: 391 LQNYHVPAGTFVIIYLYSMGRNPAVFPRP-ERYMPQRW------LERKRSFQHLAFGFGV 443 Query: 1398 RTCLGKEVAFTQMKTVAATVLWNFTLETV 1484 R CLG+ +A +M + +L F +ET+ Sbjct: 444 RQCLGRRLAEVEMLLLLHHMLKTFQVETL 472
>O00061:CP67_UROFA Cytochrome P450 67 - Uromyces fabae (Rust fungus)| Length = 541 Score = 77.8 bits (190), Expect = 1e-13 Identities = 61/224 (27%), Positives = 103/224 (45%), Gaps = 11/224 (4%) Frame = +3 Query: 852 RGEGITESSDILSFFICNDD--ASEHSDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCEN 1025 + +G+ + D+ + + D + ++ L + L+ G DTT VL FF L ++ Sbjct: 294 KNQGLGKQLDVFHYLLGEDTETGTRLTEAELAADSTLLVITGADTTRTVLLAFFLYLLKH 353 Query: 1026 PRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAALCECLRLYPSVPIT-HKAAT 1202 P + + EL +AA L LS + YL+A L E +RL P P + Sbjct: 354 PNYMEQLQAEL--LAAPD-------LSPPSLSRLEYLNACLQETMRLQPPSPANLQRICP 404 Query: 1203 HNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWIT-------DDGKLRHQ 1361 + G +I G K+ +Y++ R E + + EF P+RW+ + G+ + + Sbjct: 405 PGGAVICGRQIPEGTKVRFSNYAIHRDERYFSR-AEEFRPQRWLQKAKDDLGNQGEEKER 463 Query: 1362 PPYK-FIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLETVPG 1490 + F F GP C+ K +A+ +M+ V AT+L NF L PG Sbjct: 464 LDQRAFFGFLIGPGACVAKNLAWMEMRLVVATILTNFDLSFAPG 507
>O42563:CP3AR_ONCMY Cytochrome P450 3A27 - Oncorhynchus mykiss (Rainbow trout) (Salmo| gairdneri) Length = 518 Score = 77.8 bits (190), Expect = 1e-13 Identities = 102/436 (23%), Positives = 166/436 (38%), Gaps = 17/436 (3%) Frame = +3 Query: 303 DPSNVRHIFISNSINYPRGEEYADIFDVLGDGIFNADGESWRRQRAKSQLIMASPRFRSF 482 D S ++ + I N + L D + A+ ++WRR R+ S R + Sbjct: 87 DKSMIKTVLIKECYNIFTNRRNFHLNGELFDALSVAEDDTWRRIRSVLSPSFTSGRLKEM 146 Query: 483 SARCTRDKVERSLLPFLAHAADVGARCDLHDVLLRLMFDMTCNLVFGVDPGCLQIGLPSL 662 + +LL + AD ++ + D+ + F VD L PS Sbjct: 147 FGIMKQHS--STLLSGMKKQADKDQTIEVKEFFGPYSMDVVTSTAFSVDIDSLNN--PSD 202 Query: 663 PLARAMD-----DVLETLFLRHVIPPACWRLMYRYGFGPEKKMAVARRIIDRFAADT--I 821 P + D+ LFL + P ++ + F + D F A I Sbjct: 203 PFVSNVKKMLKFDLFNPLFLLVALFPFTGPILEKMKFS-----FFPTAVTDFFYASLAKI 257 Query: 822 VKRRYSGHKLRGEGITESSDILSFFICNDDASEH----------SDEFLRDTAVNLLFAG 971 R +G+ T D L I + S+ +D + A+ +FAG Sbjct: 258 KSGRDTGNS------TNRVDFLQLMIDSQKGSDTKTGEEQTKGLTDHEILSQAMIFIFAG 311 Query: 972 RDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAALC 1151 +T+ + +S+ Y L N V + +E+ + K + L M YL L Sbjct: 312 YETSSSTMSFLAYNLATNHHVMTKLQEEIDTVFPNK-----APIQYEALMQMDYLDCVLN 366 Query: 1152 ECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERW 1331 E LRLYP P + A V +G I +LV ++++ R +W D EF PER+ Sbjct: 367 ESLRLYPIAPRLERVAKKT-VEINGIVIPKDCIVLVPTWTLHRDPEIWS-DPEEFKPERF 424 Query: 1332 ITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLETVPGHTVKPKL 1511 ++ + PY ++ F AGPR C+G A +K +L +FT +V + Sbjct: 425 SKENKE--SIDPYTYMPFGAGPRNCIGMRFALIMIKLAMVEILQSFTF------SVCDET 476 Query: 1512 SIVLHMKNGLAVTVKR 1559 I L M N + KR Sbjct: 477 EIPLEMDNQGLLMPKR 492
>P33268:CP3A8_MACFA Cytochrome P450 3A8 - Macaca fascicularis (Crab eating macaque)| (Cynomolgus monkey) Length = 503 Score = 77.8 bits (190), Expect = 1e-13 Identities = 110/498 (22%), Positives = 194/498 (38%), Gaps = 20/498 (4%) Frame = +3 Query: 132 KKTTKEEPTEWPLLGHLLSTLANVSNLHDWATGVLATTRYN--FAAHMGLTGVRFFLTCD 305 KK PT PLLG++LS W + +Y + + G V D Sbjct: 34 KKLGIPGPTPLPLLGNILSYRKGF-----WTFDMECYKKYGKVWGFYDGRQPV--LAITD 86 Query: 306 PSNVRHIFISNSINYPRGEEYADIFDVLGDGIFNADGESWRRQRAKSQLIMASPRFRSFS 485 P+ ++ + + + + + I A+ E W+R R+ + SP F S Sbjct: 87 PNMIKTVLVKECYSVFTNRRPFGPVGFMKNAISIAEDEEWKRIRS-----LLSPTFTSGK 141 Query: 486 ARCTRDKVERS---LLPFLAHAADVGARCDLHDVLLRLMFDMTCNLVFGVDPGCLQIGLP 656 + + + L+ L A+ G L DV D+ + FGV+ L P Sbjct: 142 LKEMVPIIAKYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLNN--P 199 Query: 657 SLPLARAMD-----DVLETLFLRHVIPPACWRLM--YRYGFGPEKKMAVARRIIDRFAAD 815 P D L+ FL I P ++ P + + R+ + R Sbjct: 200 QDPFVENTKKLLRFDFLDPFFLSITIFPFIIPILEVLNISIFPREVTSFLRKSVKRIKES 259 Query: 816 TIVKRRYSGHKLRGEGITESSDILSFFICNDDASEH------SDEFLRDTAVNLLFAGRD 977 + + H++ D L I + ++ E SD L ++ +FAG + Sbjct: 260 RL--KDTQKHRV---------DFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGYE 308 Query: 978 TTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAALCEC 1157 TT +VLS+ Y L +P V+Q + +E+ + K + M YL + E Sbjct: 309 TTSSVLSFIIYELATHPDVQQKLQEEIDTVLPNKAPPTY-----DTVLQMEYLDMVVNET 363 Query: 1158 LRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWIT 1337 LR++P + + + DV +G I G +++ SY++ W + +F PER+ Sbjct: 364 LRIFP-IAMRLERVCKKDVEINGIFIPKGVVVMIPSYALHHDPKYWPEP-EKFLPERFSK 421 Query: 1338 DDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLETVPGHTVKPKLSI 1517 + + PY + F +GPR C+G A MK VL NF+ + + KL + Sbjct: 422 KNND--NIDPYIYTPFGSGPRNCIGMRFALMNMKLAIIRVLQNFSFKPCKETQIPLKLRL 479 Query: 1518 --VLHMKNGLAVTVKRRN 1565 +L + + + ++ R+ Sbjct: 480 GGLLQTEKPIVLKIESRD 497
>P05184:CP3A3_HUMAN Cytochrome P450 3A3 - Homo sapiens (Human)| Length = 504 Score = 77.8 bits (190), Expect = 1e-13 Identities = 121/525 (23%), Positives = 193/525 (36%), Gaps = 39/525 (7%) Frame = +3 Query: 60 SMEHWYWF-VGLVCCFL-SYYRRLQSKKTTKEEPTEWPLLGHLLS--------------T 191 +ME W V LV +L + KK PT P LG++LS Sbjct: 8 AMETWLLLAVSLVLLYLYGTHSHGLFKKLGIPGPTPLPFLGNILSYHKGFCMFDMECHKK 67 Query: 192 LANVSNLHDWATGVLATTRYNFAAHMGLTGVRFFLTCDPSNVRHIFISNSINYPRGEEYA 371 V +D VLA T DP ++ + + + E Sbjct: 68 YGKVWGFYDGQQPVLAIT-------------------DPDMIKLVLVKECYSVFTNREPF 108 Query: 372 DIFDVLGDGIFNADGESWRRQRAKSQLIMASPRFRSFSARCTRDKVERSLLPFLAHAADV 551 + I A+ E W+R R+ + SP F S + ++P +A DV Sbjct: 109 GPVGFMKSAISIAEDEEWKRLRS-----LLSPTFTSGKLK--------EMVPIIAQYGDV 155 Query: 552 -----------GARCDLHDVLLRLMFDMTCNLVFGVDPGCLQIGLPSLPLARAMD----- 683 G L DV D+ + FGV+ L P PL Sbjct: 156 LVRNLRRERETGKPVTLKDVFGAYSMDVITSSSFGVNVDSLNN--PQDPLVENTKKLLRF 213 Query: 684 DVLETLFLRHVIPPACWRLMYRYGFGPEKKMAVARRIIDRFAADTIVKRRYSGHKLRGEG 863 D L+ FL + P ++ + V R + F + + + S + + Sbjct: 214 DFLDPFFLSITVFPFLIPIL------EVLNICVFPREVTNFLRKAVKRMKESRLE---DT 264 Query: 864 ITESSDILSFFICNDDASEH-------SDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCE 1022 D L I + S+ SD L ++ +FAG +TT +VLS+ Y L Sbjct: 265 QKHRVDFLQLMIDSHKNSKETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELAT 324 Query: 1023 NPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAAT 1202 +P V+Q + +E+ + K + M YL + E LRL+P + + + Sbjct: 325 HPDVQQKLQEEIDAVLPNKAPPTY-----DTVLQMEYLDMVVNETLRLFP-IAMRLERVC 378 Query: 1203 HNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIA 1382 DV +G I G +++ SY++ R W + +F PER+ + + PY + Sbjct: 379 KKDVEINGMFIPKGWVVMIPSYALHRDPKYWTEP-EKFLPERFSKKNKD--NIDPYIYTP 435 Query: 1383 FNAGPRTCLGKEVAFTQMKTVAATVLWNFTLETVPGHTVKPKLSI 1517 F +GPR C+G A MK VL NF+ + + KLS+ Sbjct: 436 FGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSL 480
>Q0IIF9:CP2U1_BOVIN Cytochrome P450 2U1 - Bos taurus (Bovine)| Length = 543 Score = 77.8 bits (190), Expect = 1e-13 Identities = 71/301 (23%), Positives = 132/301 (43%), Gaps = 11/301 (3%) Frame = +3 Query: 666 LARAMDDVLETLFLRHVIPPACWRLMYRYGFGPEKKMAVARRIIDRFAADTIVKRRYSGH 845 ++RA++ L T L ++ W +Y FGP K++ + + F I R S Sbjct: 255 MSRALEVCLNTQLL--LVNICSW--LYYLPFGPFKELRQIEKDLTLFLKKIIKDHRES-- 308 Query: 846 KLRGEGITESSDILSFFIC-------NDDASEHSDEFLRDTAVNLLFAGRDTTGAVLSWF 1004 + D + ++ N+ S +++L +L AG DTT L W Sbjct: 309 ----LDVENPQDFIDMYLLHVEEEKKNNSNSGFDEDYLFYIIGDLFIAGTDTTTNSLLWC 364 Query: 1005 FYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAALCECLRLYPSVPI 1184 + +P +++ I +E+A + + + ++ + M Y A + E RL VP+ Sbjct: 365 LLYMSLHPNIQEKIHEEIARVIGADRAPSL-----TDKAQMPYTEATIMEVQRLSTVVPL 419 Query: 1185 THKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQP 1364 + T + G I G IL +S+ R +W K +F P+R++ D G+L + Sbjct: 420 SIPHMTSEKTVLQGFTIPKGTIILPNLWSVHRDPAIWEKP-NDFYPDRFLDDQGQLIKKE 478 Query: 1365 PYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTL----ETVPGHTVKPKLSIVLHMK 1532 FI F G R C+G+++A ++ + +++ +FT ++ P T K L++ H Sbjct: 479 --TFIPFGIGKRVCMGEQLAKMELFLMFVSLMQSFTFVLPKDSKPILTGKYGLTLAPHPF 536 Query: 1533 N 1535 N Sbjct: 537 N 537
>Q8HYN0:CP17A_PAPCY Cytochrome P450 17A1 - Papio cynocephalus (Yellow baboon)| Length = 508 Score = 77.8 bits (190), Expect = 1e-13 Identities = 60/233 (25%), Positives = 105/233 (45%), Gaps = 11/233 (4%) Frame = +3 Query: 846 KLRGEGITESSDILSFFICNDDASEH---------SDEFLRDTAVNLLFAGRDTTGAVLS 998 K R + IT D+L N D SD + T ++ AG +TT +V+ Sbjct: 253 KFRSDSITNMLDVLMQAKMNSDNGNAGPDQDSELLSDNHILTTIGDIFGAGVETTTSVVK 312 Query: 999 WFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAALCECLRLYPSV 1178 W L NP+V++ + +E+ + + S+ + ++ L A + E LR+ P Sbjct: 313 WIVAFLLHNPQVKKKLYEEIDQNVGFSRTPTI-----SDRNRLLLLEATIREVLRIRPVA 367 Query: 1179 P--ITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWITDDGKL 1352 P I HKA + + + G +++ +++ E W + +F PER++ G Sbjct: 368 PMLIPHKANVDSSI--GEFAVDKGTHVIINLWALHHNEKEWHQPD-QFMPERFLNPAGTQ 424 Query: 1353 RHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLETVPGHTVKPKL 1511 P ++ F AGPR+C+G+ +A ++ + A +L F LE VP P L Sbjct: 425 LISPSLSYLPFGAGPRSCIGEILARQELFLIMAWLLQRFDLE-VPDDGQLPSL 476
>Q9VG40:CP134_DROME Probable cytochrome P450 313a4 - Drosophila melanogaster (Fruit fly)| Length = 478 Score = 77.8 bits (190), Expect = 1e-13 Identities = 48/182 (26%), Positives = 85/182 (46%) Frame = +3 Query: 936 LRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASE 1115 + D + ++F +TT + + LL P ++ +E+ I D+ D + Sbjct: 273 VEDESNIIVFGAFETTANAVYYTLMLLAMFPEYQERAFEEIKTIFPNTGDFDVSYADTQQ 332 Query: 1116 LSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVW 1295 MVYL L E +R+ P VP+ + + + L +G + G +I + Y M R + +W Sbjct: 333 ---MVYLDLILNESMRVIPPVPVVSRQTSQDLKLSNGIVVPKGVQIAIDIYHMHRSKKIW 389 Query: 1296 GKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTL 1475 G D F+P+ ++ + + +H PY +I F G R C+G A K A +L N+ Sbjct: 390 GPDAETFNPDHFLPHNIQDKH--PYAYIPFTKGIRNCIGWRYALISAKVTLAKLLRNYRF 447 Query: 1476 ET 1481 +T Sbjct: 448 KT 449
>O65782:C83B1_ARATH Cytochrome P450 83B1 - Arabidopsis thaliana (Mouse-ear cress)| Length = 499 Score = 77.8 bits (190), Expect = 1e-13 Identities = 92/399 (23%), Positives = 169/399 (42%), Gaps = 9/399 (2%) Frame = +3 Query: 387 LGDGIFNADGESWRRQRAKSQLIMASPRFRSFSARCTRDKVERSLLPFLAHAADVGARCD 566 LG G + A +R R + + SP R S R R++ + ++ + AAD D Sbjct: 113 LGFGQYTA---YYREMRKMCMVNLFSPN-RVASFRPVREEECQRMMDKIYKAADQSGTVD 168 Query: 567 LHDVLLRLMFDMTCNLVFGVDPGCLQIGLPS-LPLARAMDDVLETLFLRHVIPPACWRLM 743 L ++LL + C FG + + + +L TLF + P Sbjct: 169 LSELLLSFTNCVVCRQAFGKRYNEYGTEMKRFIDILYETQALLGTLFFSDLFP------- 221 Query: 744 YRYGF-----GPEKKMAVARRIIDRFAADTIVKRRYSGHKLRGEGITESSDILSFFICND 908 +GF G ++ A + +D + + ++ ++ + E TES L I D Sbjct: 222 -YFGFLDNLTGLSARLKKAFKELDTYLQE-LLDETLDPNRPKQE--TESFIDLLMQIYKD 277 Query: 909 D--ASEHSDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKK 1082 + + + E ++ ++++ G DT AV+ W L + P + DE+ R Sbjct: 278 QPFSIKFTHENVKAMILDIVVPGTDTAAAVVVWAMTYLIKYPEAMKKAQDEV-----RSV 332 Query: 1083 VDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVY 1262 + D + ++ ++ YL A + E LRL P +PI T D G++I A I V Sbjct: 333 IGDKGYVSEEDIPNLPYLKAVIKESLRLEPVIPILLHRETIADAKIGGYDIPAKTIIQVN 392 Query: 1263 SYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQ-PPYKFIAFNAGPRTCLGKEVAFTQMK 1439 ++++ R WG + EF PER++ + + + ++ + F +G R C + ++ Sbjct: 393 AWAVSRDTAAWGDNPNEFIPERFMNEHKGVDFKGQDFELLPFGSGRRMCPAMHLGIAMVE 452 Query: 1440 TVAATVLWNFTLETVPGHTVKPKLSIVLHMKNGLAVTVK 1556 A +L+ F G +KP+ I + + GLA+ K Sbjct: 453 IPFANLLYKFDWSLPKG--IKPE-DIKMDVMTGLAMHKK 488
>P48421:C83A1_ARATH Cytochrome P450 83A1 - Arabidopsis thaliana (Mouse-ear cress)| Length = 502 Score = 77.8 bits (190), Expect = 1e-13 Identities = 55/212 (25%), Positives = 102/212 (48%) Frame = +3 Query: 912 ASEHSDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDD 1091 ASE + + ++ ++++ AG DT A + W L + P Q++ A + K Sbjct: 282 ASEFTVDNVKAVILDIVVAGTDTAAAAVVWGMTYLMKYP---QVLKKAQAEVREYMKEKG 338 Query: 1092 MVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYS 1271 + ++ ++ Y A + E LR+ P +P+ A D +G++I AG + V +++ Sbjct: 339 STFVTEDDVKNLPYFRALVKETLRIEPVIPLLIPRACIQDTKIAGYDIPAGTTVNVNAWA 398 Query: 1272 MGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAA 1451 + R E WG + EF PER++ + + Y+FI F +G R C G + ++ A Sbjct: 399 VSRDEKEWGPNPDEFRPERFLEKEVDFK-GTDYEFIPFGSGRRMCPGMRLGAAMLEVPYA 457 Query: 1452 TVLWNFTLETVPGHTVKPKLSIVLHMKNGLAV 1547 +L +F + G +KP I + + GLA+ Sbjct: 458 NLLLSFNFKLPNG--MKPD-DINMDVMTGLAM 486
>Q9VL92:CP4E3_DROME Cytochrome P450 4e3 - Drosophila melanogaster (Fruit fly)| Length = 526 Score = 77.4 bits (189), Expect = 2e-13 Identities = 109/480 (22%), Positives = 192/480 (40%), Gaps = 25/480 (5%) Frame = +3 Query: 105 LSYYRRL--QSKKTTKE--EPTEWPLLGHLLSTLAN----VSNLHDWATGVLATTRYNFA 260 L Y+ R Q ++ KE PT P+LG+ N +S DW + NF Sbjct: 16 LVYFERKASQRRQLLKEFNGPTPVPILGNANRIGKNPAEILSTFFDWWYDY---GKDNFL 72 Query: 261 AHMGLTGVRFFLTCDPSNVRHIFISNSINYPRGEEYADIFDVLGDGIFNADGESWRRQRA 440 +G + + +P + +I S + + Y + LG G+ + G W + R Sbjct: 73 FWIGYSS--HIVMTNPKQLEYILNSQQL-IQKSTIYDLLHPWLGHGLLTSFGSKWHKHRK 129 Query: 441 KSQLIMASPRFRSFSARCTRDKVERSLLPFLAHAADVGAR---CDLHDVLLRLMFDMTCN 611 M +P F + + + + F+ A D + L D+ C+ Sbjct: 130 -----MITPSFHFNILQDFHEVMNENSAKFMTQLKKASAGDTIIDFQEHANYLTLDVICD 184 Query: 612 LVFGVDPGCLQIGLPSLPLARAMDDVLETLFLRHVIPPACWRLMYRYGFGPE-KKMAVAR 788 GV ++ S+ +A D+ + +R P R + PE Sbjct: 185 TAMGVPINAMEQRDSSI--VQAFRDMCYNINMRAFHPFK--RSNRVFSLTPEFSAYQKTL 240 Query: 789 RIIDRFAADTIVKRRYSGHKLRGEGITESSD-------------ILSFFICNDDASEHSD 929 + + F D I KR Y+ L+ G E D +LS I D + Sbjct: 241 KTLQDFTYDIIEKRVYA---LQNGGSKEDHDPSLPRKKMAFLDTLLSSTI---DGRPLTR 294 Query: 930 EFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDA 1109 + + + +F G DTT + +S+ YLL +P V++ + E + D + Sbjct: 295 QEIYEEVSTFMFEGHDTTTSGVSFSVYLLSRHPDVQRKLYREQCEVMGH---DMNRSVSF 351 Query: 1110 SELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEG 1289 E++ M YL + E R+YPSVP + D +G + G + + +G + Sbjct: 352 QEIAKMKYLDLFIKEAQRVYPSVPFIGRYCD-KDYDINGSIVPKGTTLNLALILLGYNDR 410 Query: 1290 VWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNF 1469 ++ KD F PER+ + P++++ F+AGPR C+G++ A ++KTV + V+ +F Sbjct: 411 IF-KDPHHFRPERFEEEK-----PAPFEYLPFSAGPRNCIGQKFALLELKTVISKVVRSF 464
>P11707:CP3A6_RABIT Cytochrome P450 3A6 - Oryctolagus cuniculus (Rabbit)| Length = 501 Score = 77.4 bits (189), Expect = 2e-13 Identities = 109/483 (22%), Positives = 184/483 (38%), Gaps = 23/483 (4%) Frame = +3 Query: 132 KKTTKEEPTEWPLLGHLLSTLANVSNLHDWATGVLATTRYNFAAHMGLTGVR--FFLTCD 305 KK PT P +G +L + W + +Y GL R + D Sbjct: 32 KKMGIPGPTPLPFIGTILEYRKGI-----WDFDIECRKKYG--KMWGLFDGRQPLMVITD 84 Query: 306 PSNVRHIFISNSINYPRGEEYADIFDVLGDGIFNADGESWRRQRAKSQLIMASPRFRSFS 485 P ++ + + + + + ++ E W+R R + SP F S Sbjct: 85 PDMIKTVLVKECYSVFTNRRSFGPVGFMKKAVSISEDEDWKRVRT-----LLSPTFTSGK 139 Query: 486 ARCTRDKVERSLLPFLAHAADV-----------GARCDLHDVLLRLMFDMTCNLVFGVDP 632 + +LP +A DV G DL ++ D+ FGV+ Sbjct: 140 LK--------EMLPIIAQYGDVLVKNLRQEAEKGKPVDLKEIFGAYSMDVITGTSFGVNI 191 Query: 633 GCLQIGLPSLPLARAMDDVLETLFLRHVIPPACWRLMYRYGFGPEKKMAVARRIIDRFAA 812 L+ P P + + +L+ F L+ P I F Sbjct: 192 DSLRN--PQDPFVKNVRRLLKFSFFDP--------LLLSITLFPFLTPIFEALHISMFPK 241 Query: 813 DTIVKRRYSGHKLRGEGITESS----DILSFFICNDDASE-HSDEFLRDT-----AVNLL 962 D + + S K++ + + + D L I + ++ E S + L D ++ +L Sbjct: 242 DVMDFLKTSVEKIKDDRLKDKQKRRVDFLQLMINSQNSKEIDSHKALDDIEVVAQSIIIL 301 Query: 963 FAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHA 1142 FAG +TT + LS+ +LL +P V+Q + +E+ + K ++ D L M YL Sbjct: 302 FAGYETTSSTLSFIMHLLATHPDVQQKLQEEIDTLLPNK---ELATYDT--LVKMEYLDM 356 Query: 1143 ALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSP 1322 + E LRLYP + DV +G I G +++ +Y++ R W + EF P Sbjct: 357 VVNETLRLYPIAGRLERVC-KKDVDINGTFIPKGTIVMMPTYALHRDPQHW-TEPDEFRP 414 Query: 1323 ERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLETVPGHTVK 1502 ER+ + + PY + F AGPR CLG A +K ++ NF+ + V Sbjct: 415 ERFSKKNKD--NINPYIYHPFGAGPRNCLGMRFALMNIKLALVRLMQNFSFKLCKETQVP 472 Query: 1503 PKL 1511 KL Sbjct: 473 LKL 475
>P08684:CP3A4_HUMAN Cytochrome P450 3A4 - Homo sapiens (Human)| Length = 503 Score = 77.4 bits (189), Expect = 2e-13 Identities = 118/516 (22%), Positives = 193/516 (37%), Gaps = 30/516 (5%) Frame = +3 Query: 60 SMEHWYWF-VGLVCCFL-SYYRRLQSKKTTKEEPTEWPLLGHLLS--------------T 191 +ME W V LV +L + KK PT P LG++LS Sbjct: 8 AMETWLLLAVSLVLLYLYGTHSHGLFKKLGIPGPTPLPFLGNILSYHKGFCMFDMECHKK 67 Query: 192 LANVSNLHDWATGVLATTRYNFAAHMGLTGVRFFLTCDPSNVRHIFISNSINYPRGEEYA 371 V +D VLA T DP ++ + + + Sbjct: 68 YGKVWGFYDGQQPVLAIT-------------------DPDMIKTVLVKECYSVFTNRRPF 108 Query: 372 DIFDVLGDGIFNADGESWRRQRAKSQLIMASPRFRSFSARCTRDKVERS---LLPFLAHA 542 + I A+ E W+R R+ + SP F S + + + L+ L Sbjct: 109 GPVGFMKSAISIAEDEEWKRLRS-----LLSPTFTSGKLKEMVPIIAQYGDVLVRNLRRE 163 Query: 543 ADVGARCDLHDVLLRLMFDMTCNLVFGVDPGCLQIGLPSLPLARAMD-----DVLETLFL 707 A+ G L DV D+ + FGV+ L P P D L+ FL Sbjct: 164 AETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLNN--PQDPFVENTKKLLRFDFLDPFFL 221 Query: 708 RHVIPPACWRLMYRYGFGPEKKMAVARRIIDRFAADTIVKRRYSGHKLRGEGITESSDIL 887 + P ++ + V R + F ++ + + S + + D L Sbjct: 222 SITVFPFLIPIL------EVLNICVFPREVTNFLRKSVKRMKESRLE---DTQKHRVDFL 272 Query: 888 SFFICNDDASEH------SDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMIL 1049 I + ++ E SD L ++ +FAG +TT +VLS+ Y L +P V+Q + Sbjct: 273 QLMIDSQNSKETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQ 332 Query: 1050 DELAPIAARKKVDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGH 1229 +E+ + K + M YL + E LRL+P + + + DV +G Sbjct: 333 EEIDAVLPNKAPPTY-----DTVLQMEYLDMVVNETLRLFP-IAMRLERVCKKDVEINGM 386 Query: 1230 EIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCL 1409 I G +++ SY++ R W + +F PER+ + + PY + F +GPR C+ Sbjct: 387 FIPKGVVVMIPSYALHRDPKYWTEP-EKFLPERFSKKNKD--NIDPYIYTPFGSGPRNCI 443 Query: 1410 GKEVAFTQMKTVAATVLWNFTLETVPGHTVKPKLSI 1517 G A MK VL NF+ + + KLS+ Sbjct: 444 GMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSL 479
>Q8HYN1:CP17A_PANTR Cytochrome P450 17A1 - Pan troglodytes (Chimpanzee)| Length = 508 Score = 77.4 bits (189), Expect = 2e-13 Identities = 61/233 (26%), Positives = 105/233 (45%), Gaps = 11/233 (4%) Frame = +3 Query: 846 KLRGEGITESSDILSFFICNDDASEH---------SDEFLRDTAVNLLFAGRDTTGAVLS 998 K R + IT D L N D SD + T ++ AG +TT +V+ Sbjct: 253 KFRSDSITNMLDTLMQAKMNSDNGNAGPDQDSELLSDNHILTTIGDIFGAGVETTTSVVK 312 Query: 999 WFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAALCECLRLYPSV 1178 W L NP+V++ + +E+ + + S+ + ++ L A + E LRL P Sbjct: 313 WTLAFLLHNPQVKKKLYEEIDQNVGFSRTPTI-----SDRNRLLLLEATIREVLRLRPVA 367 Query: 1179 P--ITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWITDDGKL 1352 P I HKA + + + G ++++ +++ E W + +F PER++ G Sbjct: 368 PMLIPHKANVDSSI--GEFAVDKGTQVIINLWALHHNEKEWHQPD-QFMPERFLNPAGTQ 424 Query: 1353 RHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLETVPGHTVKPKL 1511 P ++ F AGPR+C+G+ +A ++ + A +L F LE VP P L Sbjct: 425 LISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRFDLE-VPDDGQLPSL 476
>P05093:CP17A_HUMAN Cytochrome P450 17A1 - Homo sapiens (Human)| Length = 508 Score = 77.4 bits (189), Expect = 2e-13 Identities = 61/233 (26%), Positives = 105/233 (45%), Gaps = 11/233 (4%) Frame = +3 Query: 846 KLRGEGITESSDILSFFICNDDASEH---------SDEFLRDTAVNLLFAGRDTTGAVLS 998 K R + IT D L N D SD + T ++ AG +TT +V+ Sbjct: 253 KFRSDSITNMLDTLMQAKMNSDNGNAGPDQDSELLSDNHILTTIGDIFGAGVETTTSVVK 312 Query: 999 WFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAALCECLRLYPSV 1178 W L NP+V++ + +E+ + + S+ + ++ L A + E LRL P Sbjct: 313 WTLAFLLHNPQVKKKLYEEIDQNVGFSRTPTI-----SDRNRLLLLEATIREVLRLRPVA 367 Query: 1179 P--ITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWITDDGKL 1352 P I HKA + + + G ++++ +++ E W + +F PER++ G Sbjct: 368 PMLIPHKANVDSSI--GEFAVDKGTEVIINLWALHHNEKEWHQPD-QFMPERFLNPAGTQ 424 Query: 1353 RHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLETVPGHTVKPKL 1511 P ++ F AGPR+C+G+ +A ++ + A +L F LE VP P L Sbjct: 425 LISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRFDLE-VPDDGQLPSL 476
>Q98T91:C340_ORYLA Cytochrome P450 3A40 - Oryzias latipes (Medaka fish) (Japanese| ricefish) Length = 502 Score = 77.4 bits (189), Expect = 2e-13 Identities = 110/494 (22%), Positives = 185/494 (37%), Gaps = 21/494 (4%) Frame = +3 Query: 51 LY*SMEHWYWFVGLVCCFL--SYYRRLQSKKTTKEEPTEWPLLGHLLSTLANVSNLHDWA 224 LY S E W V + L +Y+ K+ P P G +L+ N D Sbjct: 5 LYFSAETWTLLVAFITLLLVYAYWPYGTFKRLGIPGPKPVPFFGTMLAYRKGFFNFDD-- 62 Query: 225 TGVLATTRYNFAAHMGLTGVRFFLTC--DPSNVRHIFISNSINYPRGEEYADIFDVLGDG 398 R + G+ R + C DP+ ++ + + + + L D Sbjct: 63 -----ECRKKYGKTWGIYDGRQPVLCITDPATIKAVLVKECYSLFTNRRNFRLNGPLYDA 117 Query: 399 IFNADGESWRRQRAKSQLIMASPRFRSFSARCTRDKVER---SLLPFLAHAADVGARCDL 569 + A+ + W+R R+ + SP F S + D ++ +L+ + D ++ Sbjct: 118 VSIAEDDQWKRIRS-----VLSPSFTSGRLKEMFDIMKHHSANLIQSMKKKVDKDEPLEM 172 Query: 570 HDVLLRLMFDMTCNLVFGVDPGCLQIGLPSLPLARAMD-----DVLETLFLRHVIPPACW 734 + D+ + F VD L PS P + D L LFL P Sbjct: 173 KEYFGPYSMDVVTSTAFSVDIDSLNN--PSDPFVTNIKKMLKFDFLNPLFLAVAFFPFLG 230 Query: 735 RLMYRYGFG--PEKKMAVARRIIDRFAADTIVKRRYSGHKLRGEGITESSDILSFFICND 908 ++ ++ F P M FAA +K + +K + D L I + Sbjct: 231 PILEKFEFSLFPSSVMDFF------FAALRKIKANHENNKQKSR-----IDFLQLMIDSQ 279 Query: 909 DASEH-------SDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPI 1067 +++ SD + A+ +FAG +TT + L++ Y L NP V + + E+ Sbjct: 280 KNNQNGLQDKGLSDHEILSQAMIFIFAGYETTSSSLTFLAYNLATNPEVMKKLQKEIDAT 339 Query: 1068 AARKKVDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGD 1247 K V L M YL + E LRLYP + A V +G I Sbjct: 340 FPNKAPVQYV-----PLMEMEYLDCVVNESLRLYPIAARLERVAKAT-VEVNGLVIPKDM 393 Query: 1248 KILVYSYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAF 1427 ++V ++ + R +W + +F PER+ ++ PY ++ F AGPR C+G A Sbjct: 394 VVMVPTWPLHRDPELWPEP-EKFKPERFSKENKDTFD--PYTYMPFGAGPRNCIGMRFAL 450 Query: 1428 TQMKTVAATVLWNF 1469 MK +L + Sbjct: 451 VMMKLAVVEILQTY 464
>O17624:C13B1_CAEEL Putative cytochrome P450 cyp-13B1 - Caenorhabditis elegans| Length = 527 Score = 77.4 bits (189), Expect = 2e-13 Identities = 93/394 (23%), Positives = 167/394 (42%), Gaps = 35/394 (8%) Frame = +3 Query: 399 IFNADGESWRRQRAKSQLIMASPRFRSFSARCTRDKVERSLLPFLAHAA--DVGARCDLH 572 +F + G W+R RA +ASP F + + D +E S + + A + G ++H Sbjct: 120 LFTSRGARWKRLRA-----LASPGFSVKALKQVHDVMEDSAINMVDLMAKHEDGKPFNIH 174 Query: 573 DVLLRLMFDMTCNLVFGVDPGCLQIGLPSLPLARAMD-DVLETLFLR-HVIPPACW---- 734 +D+ L +G P+ L ++++++F+R H + P + Sbjct: 175 AYFQEFTYDVISRLA---------MGQPNSELFNNSGVEIVKSIFMRTHRVLPWYFTVLF 225 Query: 735 --------RLMYRY----GFGPEKKMAVARRIIDRFAADTIVKRRYSGHKLRGEGITESS 878 R+ Y + G EK + + ++ ++ + ++ R KL E + Sbjct: 226 PQFEHLVKRMFYNHAAVQGGDIEKLLLICKKTVE-----SRIQEREENAKLGFENA--EN 278 Query: 879 DILSFFICNDDASEHSDEF-----LRDTAVNL-------LFAGRDTTGAVLSWFFYLLCE 1022 D + F+ EF + TA ++ L AG DTT L++ YLL + Sbjct: 279 DFIDMFLNYYSEQVEDIEFGSTVEKKVTAEDVIGACFVFLLAGFDTTANSLAYASYLLAK 338 Query: 1023 NPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAAT 1202 +P ++ +E+ + + V +++ + YL A + E LRLYP + A + Sbjct: 339 HPEKMKLAQEEVDTVVGSENVS------YDDMTKLKYLDAVVRESLRLYP---VAWFACS 389 Query: 1203 HNDVLPS---GHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYK 1373 V P+ I G KI S+ R + +WG++ +F PERW+ RH Sbjct: 390 RECVKPTTLGDIYIDKGVKIEADVMSLHRSKEIWGENADDFVPERWLEPSS--RHT--MS 445 Query: 1374 FIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTL 1475 +I F AGPR C+G + ++ KT A +L + L Sbjct: 446 WIPFGAGPRQCVGMRLGLSEAKTALAHLLRRYDL 479
>Q5UQ90:YL532_MIMIV Cytochrome P450-like protein L532 - Mimivirus| Length = 468 Score = 77.0 bits (188), Expect = 2e-13 Identities = 95/427 (22%), Positives = 169/427 (39%), Gaps = 1/427 (0%) Frame = +3 Query: 282 VRFFLTCDPSNVRHIFISNSINYPRGEEYADIFDVLGDGIFNADGES-WRRQRAKSQLIM 458 V+ L D + + + NSI RG Y + G GIF ++ S W +QR + Sbjct: 82 VKMCLVFDGELTKKLLLDNSIR--RGGLYNLLTKFFGKGIFTSNIHSRWMKQRKAIFKLF 139 Query: 459 ASPRFRSFSARCTRDKVERSLLPFLAHAADVGARCDLHDVLLRLMFDMTCNLVFGVDPGC 638 + + T E L + DL VL + C ++FGVD Sbjct: 140 SPQNLIQITPELTTSMFEE-----LDRLITIKKDLDLVTVLSLIGLVGFCKVIFGVDVTD 194 Query: 639 LQIGLPSLPLARAMDDVLETLFLRHVIPPACWRLMYRYGFGPEKKMAVARRIIDRFAADT 818 + S L ++D+L +++ + P Y ++ ++ + + Sbjct: 195 M-----SEELIEPLNDLL--IYINGAVEPVLITADPSY-----RRFITNKKFVHNWMRKL 242 Query: 819 IVKRRYSGHKLRGEGITESSDILSFFICNDDASEHSDEFLRDTAVNLLFAGRDTTGAVLS 998 I K R S + E + + D + +DD +E L + ++++ G +TT ++ Sbjct: 243 IDKARKSENCF--EIMRQQLDDIG----SDDETE-----LIEFILSVVLGGHETTARLML 291 Query: 999 WFFYLLCENPRVEQMILDELAPIAARKKVDDMVVLDASELSSMVYLHAALCECLRLYPSV 1178 Y +C N + + + +E D+ D L YL+ + E RL+P V Sbjct: 292 GIIYSVCHNKEIIEKLNNE---------TDEYPKGDYINLKKRPYLNNIIKEGTRLFPPV 342 Query: 1179 PITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRMEGVWGKDCMEFSPERWITDDGKLRH 1358 + + A ND H K G + L+ + R VWG + +F PER+ D K + Sbjct: 343 WLLSREAK-NDTTIDNHFFKKGTQFLISPLIILRDYNVWGSNAEKFDPERFSNMDPKSKA 401 Query: 1359 QPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVLWNFTLETVPGHTVKPKLSIVLHMKNG 1538 Y I F G C GK+ A + V + + + + TV H + P + + + Sbjct: 402 SKLY--IPFIVGSEDCPGKKFAILESAIVVSKLFKEYEI-TVLKHKLNPMSAGTFRLSDK 458 Query: 1539 LAVTVKR 1559 L V++K+ Sbjct: 459 LPVSIKK 465
>Q7Z449:CP2U1_HUMAN Cytochrome P450 2U1 - Homo sapiens (Human)| Length = 544 Score = 77.0 bits (188), Expect = 2e-13 Identities = 63/265 (23%), Positives = 115/265 (43%), Gaps = 7/265 (2%) Frame = +3 Query: 741 MYRYGFGPEKKMAVARRIIDRFAADTIVKRRYSGHKLRGEGITESSDILSFFIC------ 902 +Y FGP K++ + I F I + S + D + ++ Sbjct: 276 LYYLPFGPFKELRQIEKDITSFLKKIIKDHQESLDR------ENPQDFIDMYLLHMEEER 329 Query: 903 -NDDASEHSDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARK 1079 N+ S +E+L +L AG DTT L W + NP V++ + +E+ + Sbjct: 330 KNNSNSSFDEEYLFYIIGDLFIAGTDTTTNSLLWCLLYMSLNPDVQEKVHEEIERVIGAN 389 Query: 1080 KVDDMVVLDASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILV 1259 + + ++ + M Y A + E RL VP+ T + + G+ I G IL Sbjct: 390 RAPSL-----TDKAQMPYTEATIMEVQRLTVVVPLAIPHMTSENTVLQGYTIPKGTLILP 444 Query: 1260 YSYSMGRMEGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMK 1439 +S+ R +W K +F P R++ D G+L + FI F G R C+G+++A ++ Sbjct: 445 NLWSVHRDPAIWEKP-EDFYPNRFLDDQGQLIKKE--TFIPFGIGKRVCMGEQLAKMELF 501 Query: 1440 TVAATVLWNFTLETVPGHTVKPKLS 1514 + +++ +F +P + KP L+ Sbjct: 502 LMFVSLMQSFAF-ALPEDSKKPLLT 525
>P04798:CP1A1_HUMAN Cytochrome P450 1A1 - Homo sapiens (Human)| Length = 512 Score = 77.0 bits (188), Expect = 2e-13 Identities = 51/167 (30%), Positives = 79/167 (47%) Frame = +3 Query: 924 SDEFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKVDDMVVL 1103 SDE + + ++L AG DT +SW L NPRV++ I +EL + R + + Sbjct: 303 SDEKIINIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRL--- 359 Query: 1104 DASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRM 1283 S+ S + Y+ A + E R VP T +T D G I G + V + + Sbjct: 360 --SDRSHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHD 417 Query: 1284 EGVWGKDCMEFSPERWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVA 1424 + +W + EF PER++T DG + K I F G R C+G+ +A Sbjct: 418 QKLW-VNPSEFLPERFLTPDGAIDKVLSEKVIIFGMGKRKCIGETIA 463
>P79304:CP193_PIG Cytochrome P450 19 type III - Sus scrofa (Pig)| Length = 501 Score = 77.0 bits (188), Expect = 2e-13 Identities = 90/392 (22%), Positives = 167/392 (42%), Gaps = 11/392 (2%) Frame = +3 Query: 399 IFNADGESWRRQRAKSQLIMASPRFRSFSARCTRDKVERSLLPFLAHAADVGARCDLHDV 578 +FN + W+ R ++ P C D + + L D+G D+ + Sbjct: 131 MFNNNPALWKAVRPFFTKALSGPGLVRMVTVCA-DSITKHLDKLEEVRNDLGY-VDVLTL 188 Query: 579 LLRLMFDMTCNLVFGV--DPGCLQIGLPSLPLARAMDDVLETLFLRHVIPPACWRLMYRY 752 + R+M D + NL G+ D L + + D + L L+ P +++ + Y Sbjct: 189 MRRIMLDTSNNLFLGIPLDESAL------VHKVQGYFDAWQALLLK---PDIFFKISWLY 239 Query: 753 GFGPEKKMAVARRIIDRFAADTIVKRRYSGHKLR-GEGITESSDILSFFICNDDASEHSD 929 K + + D A + +++ + H++ E + +S D + I + E + Sbjct: 240 ----RKYEKSVKDLKD--AMEILIEEKR--HRISTAEKLEDSMDFTTQLIFAEKRGELTK 291 Query: 930 EFLRDTAVNLLFAGRDTTGAVLSWFFYLLCENPRVEQMILDELAPIAARKKV--DDMVVL 1103 E + + ++ A DT + + +L+ +P+VE+ ++ E+ + + + DDM L Sbjct: 292 ENVNQCVLEMMIAAPDTMSITVFFMLFLIANHPQVEEELMKEIYTVVGERDIRNDDMQKL 351 Query: 1104 DASELSSMVYLHAALCECLRLYPSVPITHKAATHNDVLPSGHEIKAGDKILVYSYSMGRM 1283 E + +Y E +R P V + A +DV+ G+ +K G I++ ++GRM Sbjct: 352 KVVE--NFIY------ESMRYQPVVDFVMRKALEDDVI-DGYPVKKGTNIIL---NIGRM 399 Query: 1284 EGVWGKDCMEFSPE-RWITDDGKLRHQPPYKFIAFNAGPRTCLGKEVAFTQMKTVAATVL 1460 +EF P+ T + ++ P F F GPR C GK +A MK + T+L Sbjct: 400 HR------LEFFPKPNEFTLENFAKNVPYRYFQPFGFGPRACAGKYIAMVMMKVILVTLL 453 Query: 1461 WNFTLETVPGHTV-----KPKLSIVLHMKNGL 1541 F ++T G V K LS+ H +GL Sbjct: 454 RRFQVQTQQGQCVEKMQKKNDLSLHPHETSGL 485 Database: uniprot_sprot.fasta.out Posted date: Jul 19, 2007 5:58 PM Number of letters in database: 100,686,439 Number of sequences in database: 274,295 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 274295 Number of Hits to DB: 309,289,295 Number of extensions: 7179547 Number of successful extensions: 24267 Number of sequences better than 10.0: 704 Number of HSP's gapped: 23478 Number of HSP's successfully gapped: 734 Length of query: 599 Length of database: 100,686,439 Length adjustment: 119 Effective length of query: 480 Effective length of database: 68,045,334 Effective search space: 32661760320 Effective search space used: 32661760320 Neighboring words threshold: 12 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
