ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | FLbaf74k13 |
|---|---|
| Clone Library Name | barley_pub |
>Q9ST43:PH1_ARATH Pleckstrin homology domain-containing protein 1 - Arabidopsis| thaliana (Mouse-ear cress) Length = 145 Score = 201 bits (512), Expect = 2e-51 Identities = 95/145 (65%), Positives = 112/145 (77%), Gaps = 2/145 (1%) Frame = +3 Query: 42 MASLWRAVMGTGAPSASADATDGIEFWREPERGGWLDKQGEYIKTWRRRWFVLKQGKLFW 221 M S+WR G S + +GIEFW PER GWL KQG+YIKTWRRRWFVLK+GKL W Sbjct: 1 MESIWRIATGQ---DPSREDYEGIEFWSNPERSGWLTKQGDYIKTWRRRWFVLKRGKLLW 57 Query: 222 FKDSTVT--RASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPGETMYFVADSDKEKED 395 FKD R S PRGVI+V CLTVKGAEDV+N+ FAFELS+ TM+F+AD++KEKE+ Sbjct: 58 FKDQAAAGIRGSTPRGVISVGDCLTVKGAEDVVNKPFAFELSSGSYTMFFIADNEKEKEE 117 Query: 396 WINSIGRSIVQHSRSMTDDEIVDYD 470 WINSIGRSIVQHSRS+TD E++DYD Sbjct: 118 WINSIGRSIVQHSRSVTDSEVLDYD 142
>O08967:CYH3_MOUSE Cytohesin-3 - Mus musculus (Mouse)| Length = 399 Score = 64.3 bits (155), Expect = 6e-10 Identities = 44/154 (28%), Positives = 69/154 (44%), Gaps = 22/154 (14%) Frame = +3 Query: 27 IPPHLMASLWRAVMGTGAPSASADATDGIEFWREPERGGWLDKQGEYIKTWRRRWFVLKQ 206 +P L+ +L+ ++ D D + P+R GWL K G +KTW+RRWF+L Sbjct: 231 LPEELLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTD 290 Query: 207 GKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPGETMYFV------ 368 L++F+ T PRG+I + + L+++ ED + FEL P + Sbjct: 291 NCLYYFE---YTTDKEPRGIIPLEN-LSIREVEDP-RKPNCFELYNPSHKGQVIKACKTE 345 Query: 369 ----------------ADSDKEKEDWINSIGRSI 422 A S +EKE+W+ SI SI Sbjct: 346 ADGRVVEGNHVVYRISAPSPEEKEEWMKSIKASI 379
>Q8C4V1:RHG24_MOUSE Rho GTPase-activating protein 24 - Mus musculus (Mouse)| Length = 747 Score = 62.8 bits (151), Expect = 2e-09 Identities = 38/110 (34%), Positives = 57/110 (51%), Gaps = 10/110 (9%) Frame = +3 Query: 123 REPERGGWLDKQGEYIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGA 302 R+ + GWL KQG ++KTW RWFVLK +L++FKD T+ P G I + ++ Sbjct: 16 RKNTKCGWLRKQGGFVKTWHTRWFVLKGDQLYYFKDEDETK---PLGTIFLHGNKVIEHP 72 Query: 303 EDVLN-RKFAFELSTPG---------ETMYFVADSDKEKEDWINSIGRSI 422 + N KF F++ G E+ +A + + EDW+ SI R I Sbjct: 73 CNEENPGKFLFDVVPGGERDRMTANHESYLLMASTQNDMEDWVKSIRRVI 122
>Q8N264:RHG24_HUMAN Rho GTPase-activating protein 24 - Homo sapiens (Human)| Length = 748 Score = 62.8 bits (151), Expect = 2e-09 Identities = 40/107 (37%), Positives = 54/107 (50%), Gaps = 13/107 (12%) Frame = +3 Query: 141 GWLDKQGEYIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNR 320 GWL KQG ++KTW RWFVLK +L++FKD T+ P G I + K +E N Sbjct: 24 GWLRKQGGFVKTWHTRWFVLKGDQLYYFKDEDETK---PLGTIFLPG---NKVSEHPCNE 77 Query: 321 ----KFAFELSTPG---------ETMYFVADSDKEKEDWINSIGRSI 422 KF FE+ G E+ +A + + EDW+ SI R I Sbjct: 78 ENPGKFLFEVVPGGDRDRMTANHESYLLMASTQNDMEDWVKSIRRVI 124
>Q5U2Z7:RHG24_RAT Rho GTPase-activating protein 24 - Rattus norvegicus (Rat)| Length = 748 Score = 61.6 bits (148), Expect = 4e-09 Identities = 37/104 (35%), Positives = 52/104 (50%), Gaps = 10/104 (9%) Frame = +3 Query: 141 GWLDKQGEYIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVK-GAEDVLN 317 GWL KQG ++KTW RWFVLK +L +FKD T+ P G I + ++ + Sbjct: 23 GWLRKQGGFVKTWHTRWFVLKGDQLHYFKDEDETK---PLGTIFLPGNKVIEHPCNEESP 79 Query: 318 RKFAFELSTPG---------ETMYFVADSDKEKEDWINSIGRSI 422 KF FE+ G E+ +A + + EDW+ SI R I Sbjct: 80 GKFLFEVVPGGERDRMTANHESYLLMASTQNDMEDWVKSIRRVI 123
>Q9UIA0:CYH4_HUMAN Cytohesin-4 - Homo sapiens (Human)| Length = 394 Score = 60.1 bits (144), Expect = 1e-08 Identities = 43/156 (27%), Positives = 69/156 (44%), Gaps = 22/156 (14%) Frame = +3 Query: 27 IPPHLMASLWRAVMGTGAPSASADATDGIEFWREPERGGWLDKQGEYIKTWRRRWFVLKQ 206 +P + +L+ ++ D D + P+R GWL K G +KTW+RRWF+L Sbjct: 226 LPEDQLRNLFDSIKSEPFSIPEDDGNDLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTD 285 Query: 207 GKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPG------------ 350 L++F+ T PRG+I + + L+V+ +D + F EL P Sbjct: 286 NCLYYFE---FTTDKEPRGIIPLEN-LSVQKVDDP-KKPFCLELYNPSCRGQKIKACKTD 340 Query: 351 ----------ETMYFVADSDKEKEDWINSIGRSIVQ 428 E+ A S +E++ WI SI SI + Sbjct: 341 GDGRVVEGKHESYRISATSAEERDQWIESIRASITR 376
>Q76MY7:CYH2_CERAE Cytohesin-2 - Cercopithecus aethiops (Green monkey) (Grivet)| Length = 399 Score = 60.1 bits (144), Expect = 1e-08 Identities = 42/154 (27%), Positives = 71/154 (46%), Gaps = 22/154 (14%) Frame = +3 Query: 27 IPPHLMASLWRAVMGTGAPSASADATDGIEFWREPERGGWLDKQGEYIKTWRRRWFVLKQ 206 +P L+ +L+ ++ D D + P+R GWL K G +KTW+RRWF+L Sbjct: 226 LPEELLRNLYDSIRNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTD 285 Query: 207 GKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTP------------- 347 L++F+ T PRG+I + + L+++ +D + FEL P Sbjct: 286 NCLYYFE---YTTDKEPRGIIPLEN-LSIREVDDP-RKPNCFELYIPNNKGQLIKACKTE 340 Query: 348 -------GETMYF--VADSDKEKEDWINSIGRSI 422 G M + A + +EK++WI SI ++ Sbjct: 341 ADGRVVEGNHMVYRISAPTQEEKDEWIKSIQAAV 374
>Q7Z5H3:RHG22_HUMAN Rho GTPase-activating protein 22 - Homo sapiens (Human)| Length = 698 Score = 59.7 bits (143), Expect = 1e-08 Identities = 36/110 (32%), Positives = 56/110 (50%), Gaps = 14/110 (12%) Frame = +3 Query: 135 RGGWLDKQGEYIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVK---GAE 305 + GWL KQ +K W++RWFVL+ +LF++KD + P+G I++ + G E Sbjct: 40 KAGWLKKQRSIMKNWQQRWFVLRGDQLFYYKDKDEIK---PQGFISLQGTQVTELPPGPE 96 Query: 306 DVLNRKFAFELSTPG-----------ETMYFVADSDKEKEDWINSIGRSI 422 D K FE+S G E + +A S ++ EDW+ +I R I Sbjct: 97 D--PGKHLFEISPGGAGEREKVPANPEALLLMASSQRDMEDWVQAIRRVI 144
>P97696:CYH3_RAT Cytohesin-3 - Rattus norvegicus (Rat)| Length = 400 Score = 59.7 bits (143), Expect = 1e-08 Identities = 44/155 (28%), Positives = 69/155 (44%), Gaps = 23/155 (14%) Frame = +3 Query: 27 IPPHLMASLWRAVMGTGAPSASADATDGIEFWREPERGGWLDKQGE-YIKTWRRRWFVLK 203 +P L+ +L+ ++ D D + P+R GWL K G +KTW+RRWF+L Sbjct: 231 LPEELLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGGRVKTWKRRWFILT 290 Query: 204 QGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPGETMYFV----- 368 L++F+ T PRG+I + + L+++ ED + FEL P + Sbjct: 291 DNCLYYFE---YTTDKEPRGIIPLEN-LSIREVEDP-RKPNCFELYNPSHKGQVIKACKT 345 Query: 369 -----------------ADSDKEKEDWINSIGRSI 422 A S +EKE+W+ SI SI Sbjct: 346 EADGRVVEGNHVVYRISAPSPEEKEEWMKSIKASI 380
>O43739:CYH3_HUMAN Cytohesin-3 - Homo sapiens (Human)| Length = 400 Score = 59.7 bits (143), Expect = 1e-08 Identities = 44/155 (28%), Positives = 69/155 (44%), Gaps = 23/155 (14%) Frame = +3 Query: 27 IPPHLMASLWRAVMGTGAPSASADATDGIEFWREPERGGWLDKQGE-YIKTWRRRWFVLK 203 +P L+ +L+ ++ D D + P+R GWL K G +KTW+RRWF+L Sbjct: 231 LPEELLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGGRVKTWKRRWFILT 290 Query: 204 QGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPGETMYFV----- 368 L++F+ T PRG+I + + L+++ ED + FEL P + Sbjct: 291 DNCLYYFE---YTTDKEPRGIIPLEN-LSIREVEDP-RKPNCFELYNPSHKGQVIKACKT 345 Query: 369 -----------------ADSDKEKEDWINSIGRSI 422 A S +EKE+W+ SI SI Sbjct: 346 EADGRVVEGNHVVYRISAPSPEEKEEWMKSIKASI 380
>P97694:CYH1_RAT Cytohesin-1 - Rattus norvegicus (Rat)| Length = 398 Score = 59.7 bits (143), Expect = 1e-08 Identities = 45/155 (29%), Positives = 71/155 (45%), Gaps = 23/155 (14%) Frame = +3 Query: 27 IPPHLMASLWRAVMGTGAPSASADATDGIEFWREPERGGWLDKQGE-YIKTWRRRWFVLK 203 +P L+ +L+ ++ D D + P+R GWL K G +KTW+RRWF+L Sbjct: 227 LPEELLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGGRVKTWKRRWFILT 286 Query: 204 QGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTP------------ 347 L++F+ T PRG+I + + L+++ ED + FEL P Sbjct: 287 DNCLYYFE---YTTDKEPRGIIPLEN-LSIREVED-SKKPNCFELYIPDNKDQVIKACKT 341 Query: 348 ---------GETMYFV-ADSDKEKEDWINSIGRSI 422 T+Y + A + +EKEDWI I +I Sbjct: 342 EADGRVVEGNHTVYRISAPTPEEKEDWIKCIKAAI 376
>Q9QX11:CYH1_MOUSE Cytohesin-1 - Mus musculus (Mouse)| Length = 398 Score = 59.7 bits (143), Expect = 1e-08 Identities = 45/155 (29%), Positives = 71/155 (45%), Gaps = 23/155 (14%) Frame = +3 Query: 27 IPPHLMASLWRAVMGTGAPSASADATDGIEFWREPERGGWLDKQGE-YIKTWRRRWFVLK 203 +P L+ +L+ ++ D D + P+R GWL K G +KTW+RRWF+L Sbjct: 227 LPEELLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGGRVKTWKRRWFILT 286 Query: 204 QGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTP------------ 347 L++F+ T PRG+I + + L+++ ED + FEL P Sbjct: 287 DNCLYYFE---YTTDKEPRGIIPLEN-LSIREVED-SKKPNCFELYIPDNKDQVIKACKT 341 Query: 348 ---------GETMYFV-ADSDKEKEDWINSIGRSI 422 T+Y + A + +EKEDWI I +I Sbjct: 342 EADGRVVEGNHTVYRISAPTPEEKEDWIKCIKAAI 376
>Q9HAU0:PKHA5_HUMAN Pleckstrin homology domain-containing family A member 5 - Homo| sapiens (Human) Length = 1116 Score = 59.3 bits (142), Expect = 2e-08 Identities = 32/94 (34%), Positives = 53/94 (56%), Gaps = 2/94 (2%) Frame = +3 Query: 135 RGGWLDKQGEY-IKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDV 311 R GWL KQ +K W++RWFVL LF+++D + ++ + + + +ED Sbjct: 172 RRGWLYKQDSTGMKLWKKRWFVLSDLCLFYYRDE--KEEGILGSILLPSFQIALLTSEDH 229 Query: 312 LNRKFAFELSTPG-ETMYFVADSDKEKEDWINSI 410 +NRK+AF+ + P T YF D+ KE E W+ ++ Sbjct: 230 INRKYAFKAAHPNMRTYYFCTDTGKEMELWMKAM 263
>Q15057:CENB2_HUMAN Centaurin-beta 2 - Homo sapiens (Human)| Length = 778 Score = 58.9 bits (141), Expect = 2e-08 Identities = 41/137 (29%), Positives = 63/137 (45%), Gaps = 3/137 (2%) Frame = +3 Query: 90 SADATDGIEFWREPERGGWLDKQGEYIKTWRRRWFVLKQGKLFW---FKDSTVTRASVPR 260 + DA +GI G + KTW RRWF ++ +L + FKD+ P Sbjct: 260 NVDAANGIVM-----EGYLFKRASNAFKTWNRRWFSIQNNQLVYQKKFKDN-------PT 307 Query: 261 GVIAVASCLTVKGAEDVLNRKFAFELSTPGETMYFVADSDKEKEDWINSIGRSIVQHSRS 440 V+ TVK ED+ R+F FE+ +P ++ ADS+K ++ WI ++ SI R Sbjct: 308 VVVEDLRLCTVKHCEDI-ERRFCFEVVSPTKSCMLQADSEKLRQAWIKAVQTSIATAYRE 366 Query: 441 MTDDEIVDYDSGHPATG 491 D+ P+TG Sbjct: 367 KGDESEKLDKKSSPSTG 383
>Q8BL80:RHG22_MOUSE Rho GTPase-activating protein 22 - Mus musculus (Mouse)| Length = 702 Score = 58.2 bits (139), Expect = 4e-08 Identities = 36/109 (33%), Positives = 56/109 (51%), Gaps = 13/109 (11%) Frame = +3 Query: 135 RGGWLDKQGEYIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVL 314 + GWL KQ +K W++RWFVL+ +LF++KD S P+G I++ + D Sbjct: 46 KAGWLRKQRSIMKNWQQRWFVLRGDQLFYYKDKD---ESKPQGFISLQGTQVTELLPDPE 102 Query: 315 N-RKFAFELSTPG------------ETMYFVADSDKEKEDWINSIGRSI 422 + K FE+ TPG E + +A S ++ EDW+ +I R I Sbjct: 103 DPGKHLFEI-TPGGATEREKVPANPEALLLMASSQRDMEDWVQAIRRVI 150
>Q80YW0:CYH4_MOUSE Cytohesin-4 - Mus musculus (Mouse)| Length = 393 Score = 58.2 bits (139), Expect = 4e-08 Identities = 42/156 (26%), Positives = 69/156 (44%), Gaps = 22/156 (14%) Frame = +3 Query: 27 IPPHLMASLWRAVMGTGAPSASADATDGIEFWREPERGGWLDKQGEYIKTWRRRWFVLKQ 206 +P + +L+ ++ D D + P+R GWL K G +KTW+RRWF+L Sbjct: 226 LPEEQLRNLFDSIKSEPFSIPEDDGGDLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTD 285 Query: 207 GKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPG------------ 350 L++F+ T PRG+I + + L+V+ ED + F EL P Sbjct: 286 NCLYYFE---FTTDKEPRGIIPLEN-LSVQKVEDP-KKPFCLELYNPSCRGQKIKACKTD 340 Query: 351 ----------ETMYFVADSDKEKEDWINSIGRSIVQ 428 E+ A + +E++ WI +I SI + Sbjct: 341 GDGKVVEGKHESYRISAANAEERDQWIEAIRASITR 376
>Q15438:CYH1_HUMAN Cytohesin-1 - Homo sapiens (Human)| Length = 398 Score = 58.2 bits (139), Expect = 4e-08 Identities = 44/155 (28%), Positives = 71/155 (45%), Gaps = 23/155 (14%) Frame = +3 Query: 27 IPPHLMASLWRAVMGTGAPSASADATDGIEFWREPERGGWLDKQGE-YIKTWRRRWFVLK 203 +P L+ +L+ ++ D D + P+R GWL K G +KTW+RRWF+L Sbjct: 227 LPEELLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGGRVKTWKRRWFILT 286 Query: 204 QGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTP------------ 347 L++F+ T PRG+I + + L+++ ED + FEL P Sbjct: 287 DNCLYYFE---YTTDKEPRGIIPLEN-LSIREVED-SKKPNCFELYIPDNKDQVIKACKT 341 Query: 348 ---------GETMYFV-ADSDKEKEDWINSIGRSI 422 T+Y + A + +EKE+WI I +I Sbjct: 342 EADGRVVEGNHTVYRISAPTPEEKEEWIKCIKAAI 376
>Q76MZ1:CYH1_CERAE Cytohesin-1 - Cercopithecus aethiops (Green monkey) (Grivet)| Length = 398 Score = 58.2 bits (139), Expect = 4e-08 Identities = 44/155 (28%), Positives = 71/155 (45%), Gaps = 23/155 (14%) Frame = +3 Query: 27 IPPHLMASLWRAVMGTGAPSASADATDGIEFWREPERGGWLDKQGE-YIKTWRRRWFVLK 203 +P L+ +L+ ++ D D + P+R GWL K G +KTW+RRWF+L Sbjct: 227 LPEELLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGGRVKTWKRRWFILT 286 Query: 204 QGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTP------------ 347 L++F+ T PRG+I + + L+++ ED + FEL P Sbjct: 287 DNCLYYFE---YTTDKEPRGIIPLEN-LSIREVED-SKKPNCFELYIPDNKDQVIKACKT 341 Query: 348 ---------GETMYFV-ADSDKEKEDWINSIGRSI 422 T+Y + A + +EKE+WI I +I Sbjct: 342 EADGRVVEGNHTVYRISAPTPEEKEEWIKCIKAAI 376
>Q9W5D0:Y34F_DROME Uncharacterized protein CG12467 - Drosophila melanogaster (Fruit| fly) Length = 1561 Score = 57.8 bits (138), Expect = 5e-08 Identities = 35/91 (38%), Positives = 45/91 (49%), Gaps = 1/91 (1%) Frame = +3 Query: 132 ERGGWLDKQGEYIKTWRRRWFVLKQGKL-FWFKDSTVTRASVPRGVIAVASCLTVKGAED 308 E+ G L K G +KTWR+RWFVLK G L +W V R P+G I + + AE Sbjct: 652 EKMGHLAKLGGKLKTWRKRWFVLKNGSLNYWKSQHDVQRK--PQGQIQLDEVCRINRAEG 709 Query: 309 VLNRKFAFELSTPGETMYFVADSDKEKEDWI 401 FE+ T + Y ADS +DWI Sbjct: 710 A----STFEIDTGKKVYYLTADSHATMDDWI 736
>Q3ZBA3:PKHA2_BOVIN Pleckstrin homology domain-containing family A member 2 - Bos| taurus (Bovine) Length = 425 Score = 57.4 bits (137), Expect = 7e-08 Identities = 36/110 (32%), Positives = 52/110 (47%), Gaps = 6/110 (5%) Frame = +3 Query: 135 RGGWLDKQGEYIKTWRRRWFVLKQGKLFWFK---DSTVTRASVPRGVIAVASCLTVKGAE 305 + G+ KQG K+W+RR+F L + +FK D R + V+ CL G Sbjct: 201 KSGYCVKQGNVRKSWKRRFFALDDFTICYFKCEQDREPLRTIFLKDVLKTHECLVKSG-- 258 Query: 306 DVLNRKFAFELSTPGETMYFVADSDKEKEDWINSIGRSIVQ---HSRSMT 446 D+L R FE+ T T Y ADS ++ WI IG ++ H R M+ Sbjct: 259 DLLMRDNLFEIITSSRTFYVQADSPEDMHSWIKEIGAAVQALKCHPREMS 308
>P54644:KRAC_DICDI RAC-family serine/threonine-protein kinase homolog - Dictyostelium| discoideum (Slime mold) Length = 444 Score = 57.4 bits (137), Expect = 7e-08 Identities = 30/87 (34%), Positives = 50/87 (57%) Frame = +3 Query: 141 GWLDKQGEYIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNR 320 G+L K+G K+W++RWF+LK G L ++K VP GVI + + +K + D R Sbjct: 10 GFLTKEGGGFKSWKKRWFILKGGDLSYYK---TKGELVPLGVIHLNTSGHIKNS-DRKKR 65 Query: 321 KFAFELSTPGETMYFVADSDKEKEDWI 401 FE+ TP T + +++++E+ WI Sbjct: 66 VNGFEVQTPSRTYFLCSETEEERAKWI 92
>Q9HB19:PKHA2_HUMAN Pleckstrin homology domain-containing family A member 2 - Homo| sapiens (Human) Length = 425 Score = 57.0 bits (136), Expect = 9e-08 Identities = 33/99 (33%), Positives = 48/99 (48%), Gaps = 3/99 (3%) Frame = +3 Query: 135 RGGWLDKQGEYIKTWRRRWFVLKQGKLFWFK---DSTVTRASVPRGVIAVASCLTVKGAE 305 + G+ KQG K+W+RR+F L + +FK D R + V+ CL G Sbjct: 201 KSGYCVKQGNVRKSWKRRFFALDDFTICYFKCEQDREPLRTIFLKDVLKTHECLVKSG-- 258 Query: 306 DVLNRKFAFELSTPGETMYFVADSDKEKEDWINSIGRSI 422 D+L R FE+ T T Y ADS ++ WI IG ++ Sbjct: 259 DLLMRDNLFEIITSSRTFYVQADSPEDMHSWIKEIGAAV 297
>Q9ERS5:PKHA2_MOUSE Pleckstrin homology domain-containing family A member 2 - Mus| musculus (Mouse) Length = 425 Score = 56.6 bits (135), Expect = 1e-07 Identities = 33/99 (33%), Positives = 48/99 (48%), Gaps = 3/99 (3%) Frame = +3 Query: 135 RGGWLDKQGEYIKTWRRRWFVLKQGKLFWFK---DSTVTRASVPRGVIAVASCLTVKGAE 305 + G+ KQG K+W+RR+F L + +FK D R + V+ CL G Sbjct: 201 KSGYCVKQGNVRKSWKRRFFALDDFTICYFKCEQDREPLRTIPLKDVLKTHECLVKSG-- 258 Query: 306 DVLNRKFAFELSTPGETMYFVADSDKEKEDWINSIGRSI 422 D+L R FE+ T T Y ADS ++ WI IG ++ Sbjct: 259 DLLMRDNLFEIITTSRTFYVQADSPEDMHSWIEGIGAAV 297
>Q9WV52:PLEK2_MOUSE Pleckstrin-2 - Mus musculus (Mouse)| Length = 353 Score = 55.8 bits (133), Expect = 2e-07 Identities = 30/95 (31%), Positives = 48/95 (50%), Gaps = 1/95 (1%) Frame = +3 Query: 141 GWLDKQGEYIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNR 320 G+L K+G + W+ RWF+L+Q L ++K R + P+G I + C + NR Sbjct: 9 GFLVKRGHIVHNWKARWFILRQNTLLYYKLEGGRRVTPPKGRIVLDGCTITCPCLEYENR 68 Query: 321 KFAFELSTPGETMYFV-ADSDKEKEDWINSIGRSI 422 +L T T YF+ A S +E++ W I +I Sbjct: 69 PLLIKLKTRTSTEYFLEACSREERDSWAFEITGAI 103 Score = 33.9 bits (76), Expect = 0.81 Identities = 27/98 (27%), Positives = 43/98 (43%), Gaps = 8/98 (8%) Frame = +3 Query: 141 GWLDKQGEYIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVI----AVASCLTVKGAED 308 G+L KQG K W+ R FVL++ F + P G ++ S L G Sbjct: 252 GYLSKQGHKRKNWKVRRFVLRKDPAFLHYYDPSKEENRPVGGFSLRGSLVSALEDNGVPT 311 Query: 309 VLNRKF---AFELSTPGETMYFV-ADSDKEKEDWINSI 410 + F++ T +T Y++ A S E+ +WI +I Sbjct: 312 GVKGNVQGNLFKVITKDDTHYYIQASSKAERAEWIEAI 349
>Q9Y2H5:PKHA6_HUMAN Pleckstrin homology domain-containing family A member 6 - Homo| sapiens (Human) Length = 1048 Score = 55.8 bits (133), Expect = 2e-07 Identities = 38/131 (29%), Positives = 59/131 (45%), Gaps = 16/131 (12%) Frame = +3 Query: 135 RGGWLDKQGEY-IKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDV 311 + GWL KQ +K W +RWFVL LF++KD S+ + ++ + D Sbjct: 62 KAGWLFKQASSGVKQWNKRWFVLVDRCLFYYKDE--KEESILGSIPLLSFRVAAVQPSDN 119 Query: 312 LNRKFAFELSTPG-ETMYFVADSDKEKEDWINSIGRS--------------IVQHSRSMT 446 ++RK F+ G T +F A+S +E+E WI ++G + V+HS Sbjct: 120 ISRKHTFKAEHAGVRTYFFSAESPEEQEAWIQAMGEAARVQIPPAQKSVPQAVRHSHEKP 179 Query: 447 DDEIVDYDSGH 479 D E V H Sbjct: 180 DSENVPPSKHH 190
>Q99418:CYH2_HUMAN Cytohesin-2 - Homo sapiens (Human)| Length = 400 Score = 55.5 bits (132), Expect = 3e-07 Identities = 42/155 (27%), Positives = 71/155 (45%), Gaps = 23/155 (14%) Frame = +3 Query: 27 IPPHLMASLWRAVMGTGAPSASADATDGIEFWREPERGGWLDKQGE-YIKTWRRRWFVLK 203 +P L+ +L+ ++ D D + P+R GWL K G +KTW+RRWF+L Sbjct: 226 LPEELLRNLYDSIRNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGGRVKTWKRRWFILT 285 Query: 204 QGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTP------------ 347 L++F+ T PRG+I + + L+++ +D + FEL P Sbjct: 286 DNCLYYFE---YTTDKEPRGIIPLEN-LSIREVDDP-RKPNCFELYIPNNKGQLIKACKT 340 Query: 348 --------GETMYF--VADSDKEKEDWINSIGRSI 422 G M + A + +EK++WI SI ++ Sbjct: 341 EADGRVVEGNHMVYRISAPTQEEKDEWIKSIQAAV 375
>Q7TQG1:PKHA6_MOUSE Pleckstrin homology domain-containing family A member 6 - Mus| musculus (Mouse) Length = 1173 Score = 55.1 bits (131), Expect = 3e-07 Identities = 31/97 (31%), Positives = 52/97 (53%), Gaps = 2/97 (2%) Frame = +3 Query: 135 RGGWLDKQGEY-IKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDV 311 + GWL KQ +K W +RWFVL LF++KD + S+ + ++ + D Sbjct: 62 KAGWLYKQASSGVKQWNKRWFVLVDRCLFYYKDE--KQESILGSIPLLSFRVAAVQPSDN 119 Query: 312 LNRKFAFELSTPG-ETMYFVADSDKEKEDWINSIGRS 419 ++RK F+ G T +F A+S +E+E WI ++G + Sbjct: 120 ISRKHTFKAEHAGVRTYFFSAESPEEQEAWIQAMGEA 156
>P63035:CYH2_RAT Cytohesin-2 - Rattus norvegicus (Rat)| Length = 400 Score = 55.1 bits (131), Expect = 3e-07 Identities = 42/155 (27%), Positives = 71/155 (45%), Gaps = 23/155 (14%) Frame = +3 Query: 27 IPPHLMASLWRAVMGTGAPSASADATDGIEFWREPERGGWLDKQGE-YIKTWRRRWFVLK 203 +P L+ +L+ ++ D D + P+R GWL K G +KTW+RRWF+L Sbjct: 226 LPEDLLRNLYDSIRNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGGRVKTWKRRWFILT 285 Query: 204 QGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTP------------ 347 L++F+ T PRG+I + + L+++ +D + FEL P Sbjct: 286 DNCLYYFE---YTTDKEPRGIIPLEN-LSIREVDDP-RKPNCFELYIPNNKGQLIKACKT 340 Query: 348 --------GETMYF--VADSDKEKEDWINSIGRSI 422 G M + A + +EK++WI SI ++ Sbjct: 341 EADGRVVEGNHMVYRISAPTQEEKDEWIKSIQAAV 375
>P63034:CYH2_MOUSE Cytohesin-2 - Mus musculus (Mouse)| Length = 400 Score = 55.1 bits (131), Expect = 3e-07 Identities = 42/155 (27%), Positives = 71/155 (45%), Gaps = 23/155 (14%) Frame = +3 Query: 27 IPPHLMASLWRAVMGTGAPSASADATDGIEFWREPERGGWLDKQGE-YIKTWRRRWFVLK 203 +P L+ +L+ ++ D D + P+R GWL K G +KTW+RRWF+L Sbjct: 226 LPEDLLRNLYDSIRNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGGRVKTWKRRWFILT 285 Query: 204 QGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTP------------ 347 L++F+ T PRG+I + + L+++ +D + FEL P Sbjct: 286 DNCLYYFE---YTTDKEPRGIIPLEN-LSIREVDDP-RKPNCFELYIPNNKGQLIKACKT 340 Query: 348 --------GETMYF--VADSDKEKEDWINSIGRSI 422 G M + A + +EK++WI SI ++ Sbjct: 341 EADGRVVEGNHMVYRISAPTQEEKDEWIKSIQAAV 375
>P31748:AKT_MLVAT AKT kinase-transforming protein - AKT8 murine leukemia virus| Length = 501 Score = 55.1 bits (131), Expect = 3e-07 Identities = 38/120 (31%), Positives = 60/120 (50%), Gaps = 5/120 (4%) Frame = +3 Query: 141 GWLDKQGEYIKTWRRRWFVLK-QGKLFWFKD--STVTRASVPRGVIAVASCLTVKGAEDV 311 GWL K+GEYIKTWR R+F+LK G +K+ V + P +VA C +K Sbjct: 31 GWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDVDQRESPLNNFSVAQCQLMKTERPR 90 Query: 312 LNRKF--AFELSTPGETMYFVADSDKEKEDWINSIGRSIVQHSRSMTDDEIVDYDSGHPA 485 N + +T E + V ++ +E+E+W +I V ++E +D+ SG P+ Sbjct: 91 PNTFIIRCLQWTTVIERTFHV-ETPEEREEWATAI--QTVADGLKRQEEETMDFRSGSPS 147
>P47196:AKT1_RAT RAC-alpha serine/threonine-protein kinase - Rattus norvegicus (Rat)| Length = 480 Score = 55.1 bits (131), Expect = 3e-07 Identities = 38/120 (31%), Positives = 60/120 (50%), Gaps = 5/120 (4%) Frame = +3 Query: 141 GWLDKQGEYIKTWRRRWFVLK-QGKLFWFKD--STVTRASVPRGVIAVASCLTVKGAEDV 311 GWL K+GEYIKTWR R+F+LK G +K+ V + P +VA C +K Sbjct: 10 GWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDVEQRESPLNNFSVAQCQLMKTERPR 69 Query: 312 LNRKF--AFELSTPGETMYFVADSDKEKEDWINSIGRSIVQHSRSMTDDEIVDYDSGHPA 485 N + +T E + V ++ +E+E+W +I V ++E +D+ SG P+ Sbjct: 70 PNTFIIRCLQWTTVIERTFHV-ETPEEREEWTTAI--QTVADGLKRQEEETMDFRSGSPS 126
>P31750:AKT1_MOUSE RAC-alpha serine/threonine-protein kinase - Mus musculus (Mouse)| Length = 480 Score = 55.1 bits (131), Expect = 3e-07 Identities = 38/120 (31%), Positives = 60/120 (50%), Gaps = 5/120 (4%) Frame = +3 Query: 141 GWLDKQGEYIKTWRRRWFVLK-QGKLFWFKD--STVTRASVPRGVIAVASCLTVKGAEDV 311 GWL K+GEYIKTWR R+F+LK G +K+ V + P +VA C +K Sbjct: 10 GWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDVDQRESPLNNFSVAQCQLMKTERPR 69 Query: 312 LNRKF--AFELSTPGETMYFVADSDKEKEDWINSIGRSIVQHSRSMTDDEIVDYDSGHPA 485 N + +T E + V ++ +E+E+W +I V ++E +D+ SG P+ Sbjct: 70 PNTFIIRCLQWTTVIERTFHV-ETPEEREEWATAI--QTVADGLKRQEEETMDFRSGSPS 126
>P31749:AKT1_HUMAN RAC-alpha serine/threonine-protein kinase - Homo sapiens (Human)| Length = 480 Score = 55.1 bits (131), Expect = 3e-07 Identities = 38/120 (31%), Positives = 60/120 (50%), Gaps = 5/120 (4%) Frame = +3 Query: 141 GWLDKQGEYIKTWRRRWFVLK-QGKLFWFKD--STVTRASVPRGVIAVASCLTVKGAEDV 311 GWL K+GEYIKTWR R+F+LK G +K+ V + P +VA C +K Sbjct: 10 GWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDVDQREAPLNNFSVAQCQLMKTERPR 69 Query: 312 LNRKF--AFELSTPGETMYFVADSDKEKEDWINSIGRSIVQHSRSMTDDEIVDYDSGHPA 485 N + +T E + V ++ +E+E+W +I V ++E +D+ SG P+ Sbjct: 70 PNTFIIRCLQWTTVIERTFHV-ETPEEREEWTTAI--QTVADGLKKQEEEEMDFRSGSPS 126
>Q9NYT0:PLEK2_HUMAN Pleckstrin-2 - Homo sapiens (Human)| Length = 353 Score = 54.7 bits (130), Expect = 4e-07 Identities = 30/95 (31%), Positives = 48/95 (50%), Gaps = 1/95 (1%) Frame = +3 Query: 141 GWLDKQGEYIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNR 320 G+L K+G + W+ RWF+L+Q L ++K R + P+G I + C + NR Sbjct: 9 GFLVKRGHIVHNWKARWFILRQNTLVYYKLEGGRRVTPPKGRILLDGCTITCPCLEYENR 68 Query: 321 KFAFELSTPGETMYFV-ADSDKEKEDWINSIGRSI 422 +L T T YF+ A S +E++ W I +I Sbjct: 69 PLLIKLKTQTSTEYFLEACSREERDAWAFEITGAI 103 Score = 33.1 bits (74), Expect = 1.4 Identities = 27/98 (27%), Positives = 43/98 (43%), Gaps = 8/98 (8%) Frame = +3 Query: 141 GWLDKQGEYIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVI----AVASCLTVKGAED 308 G+L KQG K W+ R FVL++ F + P G ++ S L G Sbjct: 252 GYLAKQGHKRKNWKVRRFVLRKDPAFLHYYDPSKEENRPVGGFSLRGSLVSALEDNGVPT 311 Query: 309 VLNRKF---AFELSTPGETMYFV-ADSDKEKEDWINSI 410 + F++ T +T Y++ A S E+ +WI +I Sbjct: 312 GVKGNVQGNLFKVITKDDTHYYIQASSKAERAEWIEAI 349
>P47197:AKT2_RAT RAC-beta serine/threonine-protein kinase - Rattus norvegicus (Rat)| Length = 481 Score = 54.7 bits (130), Expect = 4e-07 Identities = 39/125 (31%), Positives = 58/125 (46%), Gaps = 5/125 (4%) Frame = +3 Query: 141 GWLDKQGEYIKTWRRRWFVLK-QGKLFWFKD--STVTRASVPRGVIAVASCLTVKGAEDV 311 GWL K+GEYIKTWR R+F+LK G +K+ + P +VA C +K Sbjct: 10 GWLHKRGEYIKTWRPRYFLLKSDGSFIGYKERPEAPDQTLPPLNNFSVAECQLMKTERPR 69 Query: 312 LNRKF--AFELSTPGETMYFVADSDKEKEDWINSIGRSIVQHSRSMTDDEIVDYDSGHPA 485 N + +T E + V DS E+E+WI +I + ++ +DY G P+ Sbjct: 70 PNTFVIRCLQWTTVIERTFHV-DSPDEREEWIRAIQMVANSLKQRGPGEDAMDYKCGSPS 128 Query: 486 TGRKS 500 S Sbjct: 129 DSSTS 133
>Q98TY9:AKT1_XENLA RAC-alpha serine/threonine-protein kinase - Xenopus laevis (African| clawed frog) Length = 481 Score = 54.7 bits (130), Expect = 4e-07 Identities = 39/117 (33%), Positives = 59/117 (50%), Gaps = 5/117 (4%) Frame = +3 Query: 141 GWLDKQGEYIKTWRRRWFVLK-QGKLFWFKD--STVTRASVPRGVIAVASCLTVKGAEDV 311 GWL K+GEYIKTWR R+F+LK G +K+ V + P +VA C +K Sbjct: 10 GWLHKRGEYIKTWRPRYFLLKSDGTFIGYKERPQDVDQLETPLNNFSVAKCQLMKTERPK 69 Query: 312 LNRKF--AFELSTPGETMYFVADSDKEKEDWINSIGRSIVQHSRSMTDDEIVDYDSG 476 N + +T E + V DS +E+E+WI I V + ++E+++ SG Sbjct: 70 PNTFIIRCLQWTTVIERTFHV-DSPEEREEWIQVIQH--VADNLKKQEEEMMEVRSG 123
>Q9H4M7:PKHA4_HUMAN Pleckstrin homology domain-containing family A member 4 - Homo| sapiens (Human) Length = 779 Score = 53.9 bits (128), Expect = 8e-07 Identities = 36/106 (33%), Positives = 53/106 (50%), Gaps = 2/106 (1%) Frame = +3 Query: 141 GWLDKQGEY-IKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLN 317 GWL KQ ++ W+RRWFVL LF++KDS SV V+ + + G Sbjct: 59 GWLHKQDSSGLRLWKRRWFVLSGHCLFYYKDS--REESVLGSVLLPSYNIRPDGPGAPRG 116 Query: 318 RKFAFELSTPG-ETMYFVADSDKEKEDWINSIGRSIVQHSRSMTDD 452 R+F F PG T AD+ ++ W+ ++GR+ SR+ DD Sbjct: 117 RRFTFTAEHPGMRTYVLAADTLEDLRGWLRALGRA----SRAEGDD 158
>P42331:RHG25_HUMAN Rho GTPase-activating protein 25 - Homo sapiens (Human)| Length = 638 Score = 53.5 bits (127), Expect = 1e-06 Identities = 38/129 (29%), Positives = 64/129 (49%), Gaps = 9/129 (6%) Frame = +3 Query: 57 RAVMGTGAPSASADATDGIEFWREPERGGWLDKQGEYIKTWRRRWFVLKQGKLFWFKDST 236 R+VM TG A+ + P + GWL KQ +K W++R+FVL+ +L+++KD Sbjct: 17 RSVM-TGEQMAAFHPSSTPNPLERPIKMGWLKKQRSIVKNWQQRYFVLRAQQLYYYKDEE 75 Query: 237 VTRASVPRGVIAVASCLTVKGAEDVLNR-KFAFEL-------STPGETMY-FVADSDKEK 389 T+ P+G + + C + A + KF FE+ + G+ Y +A S E Sbjct: 76 DTK---PQGCMYLPGCTIKEIATNPEEAGKFVFEIIPASWDQNRMGQDSYVLMASSQAEM 132 Query: 390 EDWINSIGR 416 E+W+ + R Sbjct: 133 EEWVKFLRR 141
>Q60823:AKT2_MOUSE RAC-beta serine/threonine-protein kinase - Mus musculus (Mouse)| Length = 481 Score = 53.5 bits (127), Expect = 1e-06 Identities = 38/125 (30%), Positives = 58/125 (46%), Gaps = 5/125 (4%) Frame = +3 Query: 141 GWLDKQGEYIKTWRRRWFVLK-QGKLFWFKD--STVTRASVPRGVIAVASCLTVKGAEDV 311 GWL K+GEYIKTWR R+F+LK G +K+ + P +VA C +K Sbjct: 10 GWLHKRGEYIKTWRPRYFLLKSDGSFIGYKERPEAPDQTLPPLNNFSVAECQLMKTERPR 69 Query: 312 LNRKF--AFELSTPGETMYFVADSDKEKEDWINSIGRSIVQHSRSMTDDEIVDYDSGHPA 485 N + +T E + V DS E+E+W+ +I + ++ +DY G P+ Sbjct: 70 PNTFVIRCLQWTTVIERTFHV-DSPDEREEWMRAIQMVANSLKQRGPGEDAMDYKCGSPS 128 Query: 486 TGRKS 500 S Sbjct: 129 DSSTS 133
>Q01314:AKT1_BOVIN RAC-alpha serine/threonine-protein kinase - Bos taurus (Bovine)| Length = 480 Score = 53.5 bits (127), Expect = 1e-06 Identities = 37/119 (31%), Positives = 59/119 (49%), Gaps = 5/119 (4%) Frame = +3 Query: 141 GWLDKQGEYIKTWRRRWFVLK-QGKLFWFKD--STVTRASVPRGVIAVASCLTVKGAEDV 311 GWL K+GEYIKTWR R+F+LK G +K+ + + P +VA C +K Sbjct: 10 GWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDLEQRESPLNNFSVAQCQLMKTERPR 69 Query: 312 LNRKF--AFELSTPGETMYFVADSDKEKEDWINSIGRSIVQHSRSMTDDEIVDYDSGHP 482 N + +T E + V ++ +E+E+W +I V ++E +D+ SG P Sbjct: 70 PNTFIIRCLQWTTVIERTFHV-ETPEEREEWTTAI--QTVADGLKRQEEETMDFRSGSP 125
>Q8VC98:PKHA4_MOUSE Pleckstrin homology domain-containing family A member 4 - Mus| musculus (Mouse) Length = 588 Score = 53.1 bits (126), Expect = 1e-06 Identities = 32/95 (33%), Positives = 48/95 (50%), Gaps = 2/95 (2%) Frame = +3 Query: 141 GWLDKQGEY-IKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLN 317 GWL KQ ++ W+RRWFVL LF++KDS SV V+ + + G Sbjct: 59 GWLHKQDSSGLRLWKRRWFVLSGHCLFYYKDS--REESVLGSVLLPSYSVRPDGPGAPRG 116 Query: 318 RKFAFELSTPG-ETMYFVADSDKEKEDWINSIGRS 419 R+F F PG T AD+ ++ W+ ++GR+ Sbjct: 117 RRFTFTAEHPGMRTYVLAADTLEDLRGWLRALGRA 151
>Q8BUL6:PKHA1_MOUSE Pleckstrin homology domain-containing family A member 1 - Mus| musculus (Mouse) Length = 383 Score = 53.1 bits (126), Expect = 1e-06 Identities = 31/99 (31%), Positives = 49/99 (49%), Gaps = 2/99 (2%) Frame = +3 Query: 135 RGGWLDKQGEYIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAE--D 308 + G+ KQG +K W+RR+F L + + +FK P VI + V+ + D Sbjct: 194 KAGYCVKQGAVMKNWKRRYFQLDENTIGYFKSELEKE---PLRVIPLKEVHKVQECKQSD 250 Query: 309 VLNRKFAFELSTPGETMYFVADSDKEKEDWINSIGRSIV 425 ++ R FE+ T T Y ADS +E WI ++ +IV Sbjct: 251 IMMRDNLFEIVTTSRTFYVQADSPEEMHSWIKAVSGAIV 289
>Q9HB21:PKHA1_HUMAN Pleckstrin homology domain-containing family A member 1 - Homo| sapiens (Human) Length = 404 Score = 53.1 bits (126), Expect = 1e-06 Identities = 31/99 (31%), Positives = 49/99 (49%), Gaps = 2/99 (2%) Frame = +3 Query: 135 RGGWLDKQGEYIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAE--D 308 + G+ KQG +K W+RR+F L + + +FK P VI + V+ + D Sbjct: 194 KAGYCVKQGAVMKNWKRRYFQLDENTIGYFKSELEKE---PLRVIPLKEVHKVQECKQSD 250 Query: 309 VLNRKFAFELSTPGETMYFVADSDKEKEDWINSIGRSIV 425 ++ R FE+ T T Y ADS +E WI ++ +IV Sbjct: 251 IMMRDNLFEIVTTSRTFYVQADSPEEMHSWIKAVSGAIV 289
>P31751:AKT2_HUMAN RAC-beta serine/threonine-protein kinase - Homo sapiens (Human)| Length = 481 Score = 53.1 bits (126), Expect = 1e-06 Identities = 37/120 (30%), Positives = 57/120 (47%), Gaps = 5/120 (4%) Frame = +3 Query: 141 GWLDKQGEYIKTWRRRWFVLK-QGKLFWFKD--STVTRASVPRGVIAVASCLTVKGAEDV 311 GWL K+GEYIKTWR R+F+LK G +K+ + P +VA C +K Sbjct: 10 GWLHKRGEYIKTWRPRYFLLKSDGSFIGYKERPEAPDQTLPPLNNFSVAECQLMKTERPR 69 Query: 312 LNRKF--AFELSTPGETMYFVADSDKEKEDWINSIGRSIVQHSRSMTDDEIVDYDSGHPA 485 N + +T E + V DS E+E+W+ +I + ++ +DY G P+ Sbjct: 70 PNTFVIRCLQWTTVIERTFHV-DSPDEREEWMRAIQMVANSLKQRAPGEDPMDYKCGSPS 128
>Q2KI41:CYH2_BOVIN Cytohesin-2 - Bos taurus (Bovine)| Length = 410 Score = 52.4 bits (124), Expect = 2e-06 Identities = 42/165 (25%), Positives = 71/165 (43%), Gaps = 33/165 (20%) Frame = +3 Query: 27 IPPHLMASLWRAVMGTGAPSASADATDGIEFWREPERGGWLDKQGEY-----------IK 173 +P L+ +L+ ++ D D + P+R GWL K G +K Sbjct: 226 LPEELLRNLYDSIRNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGAQAPSPPSLPGGRVK 285 Query: 174 TWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTP-- 347 TW+RRWF+L L++F+ T PRG+I + + L+++ +D + FEL P Sbjct: 286 TWKRRWFILTDNCLYYFE---YTTDKEPRGIIPLEN-LSIREVDDP-RKPNCFELYIPNN 340 Query: 348 ------------------GETMYF--VADSDKEKEDWINSIGRSI 422 G M + A + +EK++WI SI ++ Sbjct: 341 KGQLIKACKTEADGRVVEGNHMVYRISAPTQEEKDEWIKSIQAAV 385
>Q99KW3:TARA_MOUSE TRIO and F-actin-binding protein - Mus musculus (Mouse)| Length = 2014 Score = 52.0 bits (123), Expect = 3e-06 Identities = 31/112 (27%), Positives = 54/112 (48%), Gaps = 7/112 (6%) Frame = +3 Query: 108 GIEFWREPE----RGGW---LDKQGEYIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGV 266 G+ W+ P+ + GW LD+ GE W++ WFVL L +++DST A G Sbjct: 1430 GVLRWQRPDLLNFKKGWMSILDEPGE----WKKHWFVLTDSSLKYYRDSTAEEADELDGE 1485 Query: 267 IAVASCLTVKGAEDVLNRKFAFELSTPGETMYFVADSDKEKEDWINSIGRSI 422 I + SC V E + R + F++ T A + + +WI ++ +++ Sbjct: 1486 IDLRSCTDV--TEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTV 1535
>P60669:PKHA4_RAT Pleckstrin homology domain-containing family A member 4 - Rattus| norvegicus (Rat) Length = 779 Score = 52.0 bits (123), Expect = 3e-06 Identities = 31/95 (32%), Positives = 48/95 (50%), Gaps = 2/95 (2%) Frame = +3 Query: 141 GWLDKQGEY-IKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLN 317 GWL KQ ++ W+RRWFVL LF++KDS SV V+ + + G Sbjct: 59 GWLHKQDSSGLRLWKRRWFVLSGHCLFYYKDS--REESVLGSVLLPSYSVRPDGPGAPRG 116 Query: 318 RKFAFELSTPG-ETMYFVADSDKEKEDWINSIGRS 419 R+F F PG T AD+ ++ W+ ++G++ Sbjct: 117 RRFTFTAEHPGMRTYVLAADTLEDLRGWLRALGKA 151
>Q9UN19:DAPP1_HUMAN Dual adapter for phosphotyrosine and 3-phosphotyrosine and| 3-phosphoinositide - Homo sapiens (Human) Length = 280 Score = 52.0 bits (123), Expect = 3e-06 Identities = 31/105 (29%), Positives = 50/105 (47%) Frame = +3 Query: 141 GWLDKQGEYIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNR 320 G+L KQG +KTW+ RWF L + +L +FKD + P ++ + C V+ + R Sbjct: 169 GYLTKQGGLVKTWKTRWFTLHRNELKYFKDQ---MSPEPIRILDLTECSAVQ-FDYSQER 224 Query: 321 KFAFELSTPGETMYFVADSDKEKEDWINSIGRSIVQHSRSMTDDE 455 F L P T Y A + E ++WI + + Q + + E Sbjct: 225 VNCFCLVFPFRTFYLCAKTGVEADEWIKILRWKLSQIRKQLNQGE 269
>Q6IP76:AKT2B_XENLA RAC-beta serine/threonine-protein kinase-B - Xenopus laevis| (African clawed frog) Length = 485 Score = 52.0 bits (123), Expect = 3e-06 Identities = 36/96 (37%), Positives = 50/96 (52%), Gaps = 6/96 (6%) Frame = +3 Query: 141 GWLDKQGEYIKTWRRRWFVLK-QGKLFWFK---DSTVTRASVPRGVIAVASCLTVKGAED 308 GWL K+GEYIKTWR R+F+LK G +K DST P +VA C +K Sbjct: 10 GWLQKRGEYIKTWRPRYFLLKSDGSFIGYKEKPDSTEHSLLPPLNNFSVAECQLMKTERP 69 Query: 309 VLNRKF--AFELSTPGETMYFVADSDKEKEDWINSI 410 N + +T E + V D+ +E+E+WI +I Sbjct: 70 RPNTFVIRCLQWTTVIERTFHV-DTPEEREEWIIAI 104
>Q6IQ23:PKHA7_HUMAN Pleckstrin homology domain-containing family A member 7 - Homo| sapiens (Human) Length = 1121 Score = 51.6 bits (122), Expect = 4e-06 Identities = 38/122 (31%), Positives = 59/122 (48%), Gaps = 22/122 (18%) Frame = +3 Query: 141 GWLDKQGEY-IKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVAS-CLTVKGAEDVL 314 GWL KQ ++ W+RRWFVL LF++KDS R G I + S ++ ED + Sbjct: 169 GWLHKQDSSGMRLWKRRWFVLADYCLFYYKDS---REEAVLGSIPLPSYVISPVAPEDRI 225 Query: 315 NRKFAFEL------------STPG--------ETMYFVADSDKEKEDWINSIGRSIVQHS 434 +RK++F+ ST G T YF AD+ ++ W+ ++ ++ S Sbjct: 226 SRKYSFKAVHTGMRALIYNSSTAGSQAEQSGMRTYYFSADTQEDMNAWVRAMNQAAQVLS 285 Query: 435 RS 440 RS Sbjct: 286 RS 287
>Q9QXT1:DAPP1_MOUSE Dual adapter for phosphotyrosine and 3-phosphotyrosine and| 3-phosphoinositide - Mus musculus (Mouse) Length = 280 Score = 51.2 bits (121), Expect = 5e-06 Identities = 29/87 (33%), Positives = 45/87 (51%) Frame = +3 Query: 141 GWLDKQGEYIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNR 320 G+L KQG +KTW+ RWF L++ +L +FKD + P ++ + C V+ + R Sbjct: 169 GYLTKQGGLVKTWKTRWFTLQRNELKYFKDQ---MSPEPIRILDLTECSAVQ-FDYSQER 224 Query: 321 KFAFELSTPGETMYFVADSDKEKEDWI 401 F L P T Y A + E ++WI Sbjct: 225 VNCFCLVFPFRTFYLCAKTGVEADEWI 251
>Q9H2D6:TARA_HUMAN TRIO and F-actin-binding protein - Homo sapiens (Human)| Length = 2365 Score = 50.1 bits (118), Expect = 1e-05 Identities = 32/121 (26%), Positives = 54/121 (44%), Gaps = 16/121 (13%) Frame = +3 Query: 108 GIEFWREPE----RGGW---LDKQGE---------YIKTWRRRWFVLKQGKLFWFKDSTV 239 G+ WR P+ + GW LD+ GE W++ WFVL L +++DST Sbjct: 1768 GVLRWRRPDLLNFKKGWMSILDEPGEPPSPSLTTTSTSQWKKHWFVLTDSSLKYYRDSTA 1827 Query: 240 TRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPGETMYFVADSDKEKEDWINSIGRS 419 A G I + SC V E + R + F++ T A + + +WI ++ ++ Sbjct: 1828 EEADELDGEIDLRSCTDV--TEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKT 1885 Query: 420 I 422 + Sbjct: 1886 V 1886
>Q9HD67:MYO10_HUMAN Myosin-X - Homo sapiens (Human)| Length = 2058 Score = 50.1 bits (118), Expect = 1e-05 Identities = 31/117 (26%), Positives = 56/117 (47%), Gaps = 5/117 (4%) Frame = +3 Query: 123 REPERGGWLDKQGEYIKT-----WRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCL 287 +E + GWL K+G T W++RWFVL+Q KL +F++ + + +G + V Sbjct: 1211 QEALKQGWLHKKGGGSSTLSRRNWKKRWFVLRQSKLMYFENDSEEKL---KGTVEVR--- 1264 Query: 288 TVKGAEDVLNRKFAFELSTPGETMYFVADSDKEKEDWINSIGRSIVQHSRSMTDDEI 458 T K D ++ ++ T + +A+S ++ W S++ + TD EI Sbjct: 1265 TAKEIIDNTTKENGIDIIMADRTFHLIAESPEDASQWF-----SVLSQVHASTDQEI 1316 Score = 30.8 bits (68), Expect = 6.9 Identities = 11/28 (39%), Positives = 17/28 (60%) Frame = +3 Query: 144 WLDKQGEYIKTWRRRWFVLKQGKLFWFK 227 +L +G + +W+RRW VLK WF+ Sbjct: 1181 FLYMKGGLMNSWKRRWCVLKDETFLWFR 1208
>Q96P50:CENB5_HUMAN Centaurin-beta 5 - Homo sapiens (Human)| Length = 759 Score = 50.1 bits (118), Expect = 1e-05 Identities = 32/107 (29%), Positives = 53/107 (49%), Gaps = 4/107 (3%) Frame = +3 Query: 141 GWLDKQGEY-IKTWRRRWFVLKQGKLFW---FKDSTVTRASVPRGVIAVASCLTVKGAED 308 G+L K+ KTW RRWF ++ +L + KD+ V+ +VK ED Sbjct: 231 GYLFKRASNAFKTWNRRWFSIQNSQLVYQKKLKDALTV-------VVDDLRLCSVKPCED 283 Query: 309 VLNRKFAFELSTPGETMYFVADSDKEKEDWINSIGRSIVQHSRSMTD 449 + R+F FE+ +P ++ ADS+K ++ W+ ++ SI R D Sbjct: 284 I-ERRFCFEVLSPTKSCMLQADSEKLRQAWVQAVQASIASAYRESPD 329
>P16258:OSBP1_RABIT Oxysterol-binding protein 1 - Oryctolagus cuniculus (Rabbit)| Length = 809 Score = 49.7 bits (117), Expect = 1e-05 Identities = 34/94 (36%), Positives = 52/94 (55%), Gaps = 2/94 (2%) Frame = +3 Query: 135 RGGWLDKQGEYIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASC-LTVKGAEDV 311 R GWL K YIK ++RRWFVL G L +++ R + RG I +A+ +TV ED Sbjct: 93 REGWLFKWTNYIKGYQRRWFVLSNGLLSYYRSKAEMRHTC-RGTINLATANITV---EDS 148 Query: 312 LNRKFAFELSTPG-ETMYFVADSDKEKEDWINSI 410 N F +S G +T + A S+ E++ W+ ++ Sbjct: 149 CN----FIISNGGAQTYHLKASSEVERQRWVTAL 178
>P22059:OSBP1_HUMAN Oxysterol-binding protein 1 - Homo sapiens (Human)| Length = 807 Score = 49.7 bits (117), Expect = 1e-05 Identities = 34/94 (36%), Positives = 52/94 (55%), Gaps = 2/94 (2%) Frame = +3 Query: 135 RGGWLDKQGEYIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASC-LTVKGAEDV 311 R GWL K YIK ++RRWFVL G L +++ R + RG I +A+ +TV ED Sbjct: 91 REGWLFKWTNYIKGYQRRWFVLSNGLLSYYRSKAEMRHTC-RGTINLATANITV---EDS 146 Query: 312 LNRKFAFELSTPG-ETMYFVADSDKEKEDWINSI 410 N F +S G +T + A S+ E++ W+ ++ Sbjct: 147 CN----FIISNGGAQTYHLKASSEVERQRWVTAL 176
>Q3UIL6:PKHA7_MOUSE Pleckstrin homology domain-containing family A member 7 - Mus| musculus (Mouse) Length = 1118 Score = 49.3 bits (116), Expect = 2e-05 Identities = 36/122 (29%), Positives = 57/122 (46%), Gaps = 22/122 (18%) Frame = +3 Query: 141 GWLDKQGEY-IKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVAS-CLTVKGAEDVL 314 GWL KQ ++ W+RRWFVL LF++KDS R G I + S ++ ED + Sbjct: 168 GWLHKQDSSGMRLWKRRWFVLADYCLFYYKDS---REEAVLGSIPLPSYVISPVAPEDRI 224 Query: 315 NRKFAFELSTPG--------------------ETMYFVADSDKEKEDWINSIGRSIVQHS 434 +RK++F+ G T YF AD+ ++ W+ ++ ++ S Sbjct: 225 SRKYSFKAVHTGMRALIYSTTTAGSQMEHSGMRTYYFSADTLEDMNAWVRAMNQAAQVLS 284 Query: 435 RS 440 RS Sbjct: 285 RS 286
>Q8N4B1:F109A_HUMAN Protein FAM109A - Homo sapiens (Human)| Length = 249 Score = 49.3 bits (116), Expect = 2e-05 Identities = 33/107 (30%), Positives = 52/107 (48%), Gaps = 5/107 (4%) Frame = +3 Query: 132 ERGGWLDKQGEYIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLT--VKGAE 305 + G+L K+G + RRWFVL+ LF+F+D+ + P GVI + C V+ AE Sbjct: 19 DNAGFLYKKGGRHAAYHRRWFVLRGNMLFYFEDAA---SREPVGVIILEGCTVELVEAAE 75 Query: 306 DVLNRKFAFEL---STPGETMYFVADSDKEKEDWINSIGRSIVQHSR 437 + FAF + T T A+S E W+ ++ R+ + R Sbjct: 76 E-----FAFAVRFAGTRARTYVLAAESQDAMEGWVKALSRASFDYLR 117
>P79114:MYO10_BOVIN Myosin-X - Bos taurus (Bovine)| Length = 2052 Score = 48.9 bits (115), Expect = 2e-05 Identities = 30/119 (25%), Positives = 59/119 (49%), Gaps = 8/119 (6%) Frame = +3 Query: 123 REPERGGWLDKQGEYIKT-----WRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCL 287 +E + GWL K+G T W++RWFVL+Q KL +F++ + + +G + V + Sbjct: 1205 QEALKQGWLHKKGGGSSTLSRRNWKKRWFVLRQAKLMYFENDSEEKL---KGTVEVRA-- 1259 Query: 288 TVKGAEDVLNRKFAFELSTPGETMYFVADSDKEKEDW---INSIGRSIVQHSRSMTDDE 455 K D +++ ++ T + +A+S ++ W ++ + S Q R M D++ Sbjct: 1260 -AKEIIDNTSKENGIDIIMADRTFHLIAESPEDASQWFSVLSQVHASTDQEIREMHDEQ 1317 Score = 30.8 bits (68), Expect = 6.9 Identities = 11/28 (39%), Positives = 17/28 (60%) Frame = +3 Query: 144 WLDKQGEYIKTWRRRWFVLKQGKLFWFK 227 +L +G + +W+RRW VLK WF+ Sbjct: 1175 FLYMKGGLMNSWKRRWCVLKDETFLWFR 1202
>Q7ZX15:AKT2A_XENLA RAC-beta serine/threonine-protein kinase-A - Xenopus laevis| (African clawed frog) Length = 486 Score = 48.1 bits (113), Expect = 4e-05 Identities = 35/97 (36%), Positives = 51/97 (52%), Gaps = 7/97 (7%) Frame = +3 Query: 141 GWLDKQGEYIKTWRRRWFVLK-QGKLFWFKDS-TVTRASV---PRGVIAVASCLTVKGAE 305 GWL K+GEYIKTWR R+F+LK G +K+ T +V P +VA C +K Sbjct: 10 GWLQKRGEYIKTWRPRYFLLKSDGSFIGYKEKPESTEHNVVLPPLNNFSVAECQLMKTER 69 Query: 306 DVLNRKF--AFELSTPGETMYFVADSDKEKEDWINSI 410 N + +T E + V D+ +E+E+WI +I Sbjct: 70 PRPNTFVIRCLQWTTVIERTFHV-DTPEEREEWIIAI 105
>Q8BYW1:RHG25_MOUSE Rho GTPase-activating protein 25 - Mus musculus (Mouse)| Length = 648 Score = 47.0 bits (110), Expect = 9e-05 Identities = 31/105 (29%), Positives = 53/105 (50%), Gaps = 9/105 (8%) Frame = +3 Query: 129 PERGGWLDKQGEYIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAED 308 P + GWL KQ +K W++R+FVL+ +L+++KD S P+G + + + A + Sbjct: 47 PIKVGWLKKQRSIVKNWQQRYFVLRAQQLYYYKDE---EDSKPQGCMYLPGSTVKEIATN 103 Query: 309 VLNR-KFAFEL-------STPGETMY-FVADSDKEKEDWINSIGR 416 KF FE+ + G+ Y +A S E E+W+ + R Sbjct: 104 PEEAGKFVFEVIPASSDQNRIGQDSYVLMASSQVEMEEWVKFLRR 148
>Q8INB9:AKT1_DROME RAC serine/threonine-protein kinase - Drosophila melanogaster| (Fruit fly) Length = 611 Score = 46.6 bits (109), Expect = 1e-04 Identities = 38/128 (29%), Positives = 58/128 (45%), Gaps = 12/128 (9%) Frame = +3 Query: 141 GWLDKQGEYIKTWRRRWFVL-KQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVL- 314 GWL K+GE+IK WR+R+FVL G+L ++ AS P + + TV+G + + Sbjct: 111 GWLMKRGEHIKNWRQRYFVLHSDGRLMGYRSKPADSASTPSDFL--LNNFTVRGCQIMTV 168 Query: 315 --NRKFAFELS----TPGETMYFVADSDKEKEDWINSI----GRSIVQHSRSMTDDEIVD 464 + F F + T F +S+ E++ W +I R I +MT E D Sbjct: 169 DRPKPFTFIIRGLQWTTVIERTFAVESELERQQWTEAIRNVSSRLIDVGEVAMTPSEQTD 228 Query: 465 YDSGHPAT 488 AT Sbjct: 229 MTDVDMAT 236
>Q9ERE6:MRIP_RAT Myosin phosphatase Rho-interacting protein - Rattus norvegicus| (Rat) Length = 1029 Score = 46.2 bits (108), Expect = 2e-04 Identities = 28/98 (28%), Positives = 49/98 (50%) Frame = +3 Query: 141 GWLDKQGEYIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNR 320 GWL KQ E + W++ WFVL L +++DS A+ G I +++C V E + R Sbjct: 396 GWLTKQYEDGQ-WKKHWFVLADQSLRYYRDSVAEEAADLDGEINLSTCYDV--TEYPVQR 452 Query: 321 KFAFELSTPGETMYFVADSDKEKEDWINSIGRSIVQHS 434 + F++ T A + + +WI +I + ++ S Sbjct: 453 NYGFQIHTKEGEFTLSAMTSGIRRNWIQTIMKHVLPTS 490 Score = 38.5 bits (88), Expect = 0.033 Identities = 27/105 (25%), Positives = 48/105 (45%), Gaps = 10/105 (9%) Frame = +3 Query: 126 EPERGGWL---------DKQGEYIKTWRRRWFVL-KQGKLFWFKDSTVTRASVPRGVIAV 275 +P GGWL D + W+RR+F+L + G L + D T ++P+G I + Sbjct: 43 KPIYGGWLLLAPDGTDFDNPVHRSRKWQRRFFILYEHGLLRYALDEMPT--TLPQGTINM 100 Query: 276 ASCLTVKGAEDVLNRKFAFELSTPGETMYFVADSDKEKEDWINSI 410 C V E +KF+ + TP + + A++ + W+ + Sbjct: 101 NQCTDVVDGEARTGQKFSLCILTPDKEHFIRAETKEIISGWLEML 145
>P97434:MRIP_MOUSE Myosin phosphatase Rho-interacting protein - Mus musculus (Mouse)| Length = 1024 Score = 46.2 bits (108), Expect = 2e-04 Identities = 28/98 (28%), Positives = 49/98 (50%) Frame = +3 Query: 141 GWLDKQGEYIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNR 320 GWL KQ E + W++ WFVL L +++DS A+ G I +++C V E + R Sbjct: 391 GWLTKQYEDGQ-WKKHWFVLADQSLRYYRDSVAEEAADLDGEINLSTCYDV--TEYPVQR 447 Query: 321 KFAFELSTPGETMYFVADSDKEKEDWINSIGRSIVQHS 434 + F++ T A + + +WI +I + ++ S Sbjct: 448 NYGFQIHTKEGEFTLSAMTSGIRRNWIQTIMKHVLPAS 485 Score = 38.5 bits (88), Expect = 0.033 Identities = 27/105 (25%), Positives = 48/105 (45%), Gaps = 10/105 (9%) Frame = +3 Query: 126 EPERGGWL---------DKQGEYIKTWRRRWFVL-KQGKLFWFKDSTVTRASVPRGVIAV 275 +P GGWL D + W+RR+F+L + G L + D T ++P+G I + Sbjct: 43 KPIYGGWLLLAPDGTDFDNPVHRSRKWQRRFFILYEHGLLRYALDEMPT--TLPQGTINM 100 Query: 276 ASCLTVKGAEDVLNRKFAFELSTPGETMYFVADSDKEKEDWINSI 410 C V E +KF+ + TP + + A++ + W+ + Sbjct: 101 NQCTDVVDGEARTGQKFSLCILTPDKEHFIRAETKEIISGWLEML 145
>Q6WCQ1:MRIP_HUMAN Myosin phosphatase Rho-interacting protein - Homo sapiens (Human)| Length = 1024 Score = 45.4 bits (106), Expect = 3e-04 Identities = 27/94 (28%), Positives = 47/94 (50%) Frame = +3 Query: 141 GWLDKQGEYIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNR 320 GWL KQ E + W++ WFVL L +++DS A+ G I +++C V E + R Sbjct: 391 GWLTKQYEDGQ-WKKHWFVLADQSLRYYRDSVAEEAADLDGEIDLSACYDV--TEYPVQR 447 Query: 321 KFAFELSTPGETMYFVADSDKEKEDWINSIGRSI 422 + F++ T A + + +WI +I + + Sbjct: 448 NYGFQIHTKEGEFTLSAMTSGIRRNWIQTIMKHV 481 Score = 38.9 bits (89), Expect = 0.025 Identities = 27/105 (25%), Positives = 48/105 (45%), Gaps = 10/105 (9%) Frame = +3 Query: 126 EPERGGWL---------DKQGEYIKTWRRRWFVL-KQGKLFWFKDSTVTRASVPRGVIAV 275 +P GGWL D + W+RR+F+L + G L + D T ++P+G I + Sbjct: 43 KPIYGGWLLLAPDGTDFDNPVHRSRKWQRRFFILYEHGLLRYALDEMPT--TLPQGTINM 100 Query: 276 ASCLTVKGAEDVLNRKFAFELSTPGETMYFVADSDKEKEDWINSI 410 C V E +KF+ + TP + + A++ + W+ + Sbjct: 101 NQCTDVVDGEGRTGQKFSLCILTPEKEHFIRAETKEIVSGWLEML 145
>Q9WUA6:AKT3_MOUSE RAC-gamma serine/threonine-protein kinase - Mus musculus (Mouse)| Length = 479 Score = 45.4 bits (106), Expect = 3e-04 Identities = 30/94 (31%), Positives = 46/94 (48%), Gaps = 4/94 (4%) Frame = +3 Query: 141 GWLDKQGEYIKTWRRRWFVLK-QGKLFWFKDSTV-TRASVPRGVIAVASCLTVKGAEDVL 314 GW+ K+GEYIK WR R+F+LK G +K+ P +VA C +K Sbjct: 10 GWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDLPYPLNNFSVAKCQLMKTERPKP 69 Query: 315 NRKF--AFELSTPGETMYFVADSDKEKEDWINSI 410 N + +T E + V D+ +E+E+W +I Sbjct: 70 NTFIIRCLQWTTVIERTFHV-DTPEEREEWTEAI 102
>Q9Y243:AKT3_HUMAN RAC-gamma serine/threonine-protein kinase - Homo sapiens (Human)| Length = 479 Score = 45.4 bits (106), Expect = 3e-04 Identities = 30/94 (31%), Positives = 46/94 (48%), Gaps = 4/94 (4%) Frame = +3 Query: 141 GWLDKQGEYIKTWRRRWFVLK-QGKLFWFKDSTV-TRASVPRGVIAVASCLTVKGAEDVL 314 GW+ K+GEYIK WR R+F+LK G +K+ P +VA C +K Sbjct: 10 GWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDLPYPLNNFSVAKCQLMKTERPKP 69 Query: 315 NRKF--AFELSTPGETMYFVADSDKEKEDWINSI 410 N + +T E + V D+ +E+E+W +I Sbjct: 70 NTFIIRCLQWTTVIERTFHV-DTPEEREEWTEAI 102
>P08567:PLEK_HUMAN Pleckstrin - Homo sapiens (Human)| Length = 350 Score = 44.7 bits (104), Expect = 5e-04 Identities = 25/97 (25%), Positives = 49/97 (50%), Gaps = 1/97 (1%) Frame = +3 Query: 135 RGGWLDKQGEYIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVL 314 R G+L K+G TW+ W VL + + ++K + + P+G+I + +D Sbjct: 7 REGYLVKKGSVFNTWKPMWVVLLEDGIEFYKKKS---DNSPKGMIPLKGSTLTSPCQDFG 63 Query: 315 NRKFAFEL-STPGETMYFVADSDKEKEDWINSIGRSI 422 R F F++ +T + +F A +E++ W+ I ++I Sbjct: 64 KRMFVFKITTTKQQDHFFQAAFLEERDAWVRDIKKAI 100 Score = 38.5 bits (88), Expect = 0.033 Identities = 29/95 (30%), Positives = 43/95 (45%), Gaps = 5/95 (5%) Frame = +3 Query: 141 GWLDKQGEYIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNR 320 G L KQG K W+ R F+L++ + A P G I + C+ + R Sbjct: 249 GCLLKQGHRRKNWKVRKFILREDPAY-LHYYDPAGAEDPLGAIHLRGCVVTSVESNSNGR 307 Query: 321 KF----AFELSTPGETMYFV-ADSDKEKEDWINSI 410 K FE+ T E YF+ A + KE+ +WI +I Sbjct: 308 KSEEENLFEIITADEVHYFLQAATPKERTEWIKAI 342
>Q13480:GAB1_HUMAN GRB2-associated-binding protein 1 - Homo sapiens (Human)| Length = 694 Score = 44.7 bits (104), Expect = 5e-04 Identities = 30/102 (29%), Positives = 43/102 (42%), Gaps = 12/102 (11%) Frame = +3 Query: 141 GWLDKQGEYIK----TWRRRWFVLKQGKLFWFKDSTV----TRASVPRGVIAVASCLTVK 296 GWL K K W+RRWFVL+ G+L D A P +I + C V Sbjct: 10 GWLRKSPPEKKLKRYAWKRRWFVLRSGRLTGDPDVLEYYKNDHAKKPIRIIDLNLCQQVD 69 Query: 297 GA----EDVLNRKFAFELSTPGETMYFVADSDKEKEDWINSI 410 + + F+++T Y VADS++E W+ I Sbjct: 70 AGLTFNKKEFENSYIFDINTIDRIFYLVADSEEEMNKWVRCI 111
>Q6PA69:DEFI6_XENLA Differentially expressed in FDCP 6 homolog - Xenopus laevis| (African clawed frog) Length = 596 Score = 44.7 bits (104), Expect = 5e-04 Identities = 27/103 (26%), Positives = 49/103 (47%), Gaps = 1/103 (0%) Frame = +3 Query: 141 GWLDKQGEYIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNR 320 G+L K+ +TW RWF+LK L ++ +G+I + V+ D R Sbjct: 212 GYLLKKANLRRTWTERWFILKPSSLGYYLSE---ECKERKGIITIDKDCGVEILPDRDGR 268 Query: 321 KFAFELSTPGETMYFVADSDKEKEDWINSIGRSI-VQHSRSMT 446 + F + T +T A K +++W+ +I +I +Q S S++ Sbjct: 269 RCMFCVKTTSKTHEMCASDTKHRQEWVTAIQTAIRLQQSGSLS 311
>Q27421:OSP_DROME Protein outspread - Drosophila melanogaster (Fruit fly)| Length = 1553 Score = 44.3 bits (103), Expect = 6e-04 Identities = 31/116 (26%), Positives = 51/116 (43%), Gaps = 1/116 (0%) Frame = +3 Query: 57 RAVMGTGAPSASADATDGIEFWREPERGGWLDKQGEYIKTWRRRWFVLKQGKLFWFKDST 236 R+V + S+S ++ + GWL KQ W + WF L LF+++D Sbjct: 470 RSVGKANSKSSSGQGKPPVKEESLNAKKGWLMKQDNRTCEWSKHWFTLSGAALFYYRDPL 529 Query: 237 VTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPGETMYFVAD-SDKEKEDWI 401 V GV+ V S LT E +++ AF+L+T + +A S + W+ Sbjct: 530 CEERGVLDGVLDVNS-LTSVIPEPAASKQHAFQLTTWDKQRLVLASLSPSSRNSWL 584 Score = 41.2 bits (95), Expect = 0.005 Identities = 26/96 (27%), Positives = 45/96 (46%), Gaps = 4/96 (4%) Frame = +3 Query: 171 KTWRRRWFVL-KQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTP 347 K W+RRWFVL G+L + D ++P+ + + L V A +V + ++ P Sbjct: 94 KRWQRRWFVLYDDGELTYSVDD--YPETIPQACVDMTKVLEVTSAVEVTGHPNSIAITAP 151 Query: 348 GETMYFVADSDKEKEDWINSIG---RSIVQHSRSMT 446 + S +E + W+N + +S +H RS T Sbjct: 152 ERVTFVKGTSSEESQWWLNILAAFPKSKGRHKRSAT 187
>Q9UQC2:GAB2_HUMAN GRB2-associated-binding protein 2 - Homo sapiens (Human)| Length = 676 Score = 44.3 bits (103), Expect = 6e-04 Identities = 28/105 (26%), Positives = 48/105 (45%), Gaps = 15/105 (14%) Frame = +3 Query: 141 GWLDKQGEYIK----TWRRRWFVLKQGK-------LFWFKDSTVTRASVPRGVIAVASCL 287 GWL K K W++RWF+L+ G+ L ++K+ + P +I + C Sbjct: 11 GWLRKSPPEKKLRRYAWKKRWFILRSGRMSGDPDVLEYYKND---HSKKPLRIINLNFCE 67 Query: 288 TVKGA----EDVLNRKFAFELSTPGETMYFVADSDKEKEDWINSI 410 V + L F F++ T T Y VA+++++ W+ SI Sbjct: 68 QVDAGLTFNKKELQDSFVFDIKTSERTFYLVAETEEDMNKWVQSI 112
>Q9Z1T4:CNKR2_RAT Connector enhancer of kinase suppressor of ras 2 - Rattus| norvegicus (Rat) Length = 1032 Score = 43.9 bits (102), Expect = 8e-04 Identities = 26/95 (27%), Positives = 47/95 (49%), Gaps = 5/95 (5%) Frame = +3 Query: 141 GWL----DKQGEYIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAED 308 GWL D + + + W++ WFVLK L+W+ + +A G I++ + +E Sbjct: 575 GWLWKKKDAKSYFSQKWKKYWFVLKDASLYWYINEEDEKA---EGFISLPEFKIDRASE- 630 Query: 309 VLNRKFAFELSTPG-ETMYFVADSDKEKEDWINSI 410 +K+AF+ P ++ YF A+ + W+N I Sbjct: 631 -CRKKYAFKACHPKIKSFYFAAEHLDDMNRWLNRI 664
>Q80YA9:CNKR2_MOUSE Connector enhancer of kinase suppressor of ras 2 - Mus musculus| (Mouse) Length = 1032 Score = 43.9 bits (102), Expect = 8e-04 Identities = 26/95 (27%), Positives = 47/95 (49%), Gaps = 5/95 (5%) Frame = +3 Query: 141 GWL----DKQGEYIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAED 308 GWL D + + + W++ WFVLK L+W+ + +A G I++ + +E Sbjct: 575 GWLWKKKDAKSYFSQKWKKYWFVLKDASLYWYINEEDEKA---EGFISLPEFKIDRASE- 630 Query: 309 VLNRKFAFELSTPG-ETMYFVADSDKEKEDWINSI 410 +K+AF+ P ++ YF A+ + W+N I Sbjct: 631 -CRKKYAFKACHPKIKSFYFAAEHLDDMNRWLNRI 664
>Q8WXI2:CNKR2_HUMAN Connector enhancer of kinase suppressor of ras 2 - Homo sapiens| (Human) Length = 1034 Score = 43.9 bits (102), Expect = 8e-04 Identities = 26/95 (27%), Positives = 47/95 (49%), Gaps = 5/95 (5%) Frame = +3 Query: 141 GWL----DKQGEYIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAED 308 GWL D + + + W++ WFVLK L+W+ + +A G I++ + +E Sbjct: 575 GWLWKKKDAKSYFSQKWKKYWFVLKDASLYWYINEEDEKA---EGFISLPEFKIDRASE- 630 Query: 309 VLNRKFAFELSTPG-ETMYFVADSDKEKEDWINSI 410 +K+AF+ P ++ YF A+ + W+N I Sbjct: 631 -CRKKYAFKACHPKIKSFYFAAEHLDDMNRWLNRI 664
>Q8BZ05:CEND1_MOUSE Centaurin-delta 1 - Mus musculus (Mouse)| Length = 1703 Score = 43.9 bits (102), Expect = 8e-04 Identities = 29/112 (25%), Positives = 58/112 (51%) Frame = +3 Query: 129 PERGGWLDKQGEYIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAED 308 PE+ G+L+ +G ++ + F + +G W + S I + VK + Sbjct: 586 PEKCGYLELRG-----YKAKIFTVLRGNSVWLCKNEQDFKSGLGITIIPMNVANVKQVDR 640 Query: 309 VLNRKFAFELSTPGETMYFVADSDKEKEDWINSIGRSIVQHSRSMTDDEIVD 464 + K +FE+ TP + F ADS++EK++WI ++ +SI + +++D E+ + Sbjct: 641 AV--KQSFEIITPYRSFSFTADSEREKQEWIEAVQQSIAE---TLSDYEVAE 687 Score = 36.6 bits (83), Expect = 0.12 Identities = 26/94 (27%), Positives = 47/94 (50%), Gaps = 3/94 (3%) Frame = +3 Query: 132 ERGGWLDK---QGEYIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGA 302 E+ GWLDK QG+ + +++RW + + + R +G+I + + TV+ Sbjct: 482 EKCGWLDKLSPQGK--RMFQKRWVKFDGLSISHYNND---REMYSKGIIPLTAISTVRAQ 536 Query: 303 EDVLNRKFAFELSTPGETMYFVADSDKEKEDWIN 404 D N+ FE+ T T F + ++E+ DWI+ Sbjct: 537 GD--NK---FEIVTTQRTFVFRVEKEEERNDWIS 565
>Q5XGP7:SKA2A_XENLA Src kinase-associated phosphoprotein 2-A - Xenopus laevis (African| clawed frog) Length = 330 Score = 43.5 bits (101), Expect = 0.001 Identities = 40/148 (27%), Positives = 64/148 (43%), Gaps = 11/148 (7%) Frame = +3 Query: 69 GTGAPSASADATDGIEFWREPERGGWLDKQGE----YIKTWRRRWFVLKQGKLFWF---K 227 G+ PS +A D + R G+L+K+ + + W++RW VL +++ K Sbjct: 93 GSFYPSVAAQDLDYL-------RAGYLEKRRKDHSFFASEWQKRWCVLTNSMFYYYGSDK 145 Query: 228 DSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPGETMY-FVADSDKEKEDWIN 404 D A G A + K A+ + FE+ P + +Y F A S KE E+WIN Sbjct: 146 DKQQKGAFSLDGYRAKMNDTLRKDAK----KDCCFEILAPDKRVYQFAASSPKEAEEWIN 201 Query: 405 SIGR---SIVQHSRSMTDDEIVDYDSGH 479 I +I + DD + D+ H Sbjct: 202 VIMNARGNIPSEDEELYDDVNQEMDASH 229
>Q6Q308:PLEK_CANFA Pleckstrin - Canis familiaris (Dog)| Length = 351 Score = 43.5 bits (101), Expect = 0.001 Identities = 24/97 (24%), Positives = 48/97 (49%), Gaps = 1/97 (1%) Frame = +3 Query: 135 RGGWLDKQGEYIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVL 314 R G+L K+G TW+ W VL + + ++K + + P+G+I + +D Sbjct: 7 REGYLVKRGSVFNTWKPMWVVLLEDGIEFYKKKS---DNSPKGMIPLKGSTLTSPCQDFG 63 Query: 315 NRKFAFEL-STPGETMYFVADSDKEKEDWINSIGRSI 422 R F F++ +T + +F A +E++ W+ ++I Sbjct: 64 KRMFVFKITTTKQQDHFFQAAFLEERDSWVRDTKKAI 100 Score = 41.2 bits (95), Expect = 0.005 Identities = 29/95 (30%), Positives = 45/95 (47%), Gaps = 5/95 (5%) Frame = +3 Query: 141 GWLDKQGEYIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCL--TVKGAEDV- 311 G L KQG K W+ R F+L++ + P G I + C+ +V+ DV Sbjct: 249 GCLLKQGHRRKNWKVRKFILREDPAYLHYYDPAAGGEEPLGAIHLRGCVVTSVESNPDVR 308 Query: 312 -LNRKFAFELSTPGETMYFV-ADSDKEKEDWINSI 410 + FE+ T E YF+ A + KE+ +WI +I Sbjct: 309 KSEEENLFEIITADEVHYFLQAATPKERTEWIKAI 343
>Q9EQH1:GAB2_RAT GRB2-associated-binding protein 2 - Rattus norvegicus (Rat)| Length = 665 Score = 43.5 bits (101), Expect = 0.001 Identities = 28/105 (26%), Positives = 47/105 (44%), Gaps = 15/105 (14%) Frame = +3 Query: 141 GWLDKQGEYIK----TWRRRWFVLKQGK-------LFWFKDSTVTRASVPRGVIAVASCL 287 GWL K K W++RWF+L+ G+ L ++K+ + P +I + C Sbjct: 13 GWLRKSPPEKKLRRYAWKKRWFILRSGRMSGDPDVLEYYKNE---HSKKPLRIINLNFCE 69 Query: 288 TVKGA----EDVLNRKFAFELSTPGETMYFVADSDKEKEDWINSI 410 V + L F F++ T T Y VA+++ + W+ SI Sbjct: 70 QVDAGLTFNKKELQDSFVFDIKTSERTFYLVAETEADMNKWVQSI 114
>Q9Z1S8:GAB2_MOUSE GRB2-associated-binding protein 2 - Mus musculus (Mouse)| Length = 665 Score = 43.5 bits (101), Expect = 0.001 Identities = 28/105 (26%), Positives = 47/105 (44%), Gaps = 15/105 (14%) Frame = +3 Query: 141 GWLDKQGEYIK----TWRRRWFVLKQGK-------LFWFKDSTVTRASVPRGVIAVASCL 287 GWL K K W++RWF+L+ G+ L ++K+ + P +I + C Sbjct: 13 GWLRKSPPEKKLRRYAWKKRWFILRSGRMSGDPDVLEYYKNE---HSKKPLRIINLNLCE 69 Query: 288 TVKGA----EDVLNRKFAFELSTPGETMYFVADSDKEKEDWINSI 410 V + L F F++ T T Y VA+++ + W+ SI Sbjct: 70 QVDAGLTFNKKELQDSFVFDIKTSERTFYLVAETEADMNKWVQSI 114
>Q9QYY0:GAB1_MOUSE GRB2-associated-binding protein 1 - Mus musculus (Mouse)| Length = 695 Score = 43.5 bits (101), Expect = 0.001 Identities = 29/102 (28%), Positives = 43/102 (42%), Gaps = 12/102 (11%) Frame = +3 Query: 141 GWLDKQGEYIK----TWRRRWFVLKQGKLFWFKDSTV----TRASVPRGVIAVASCLTVK 296 GWL K K W+RRWFVL+ G+L D A P +I + C V Sbjct: 10 GWLRKSPPEKKLKRYAWKRRWFVLRSGRLTGDPDVLEYYKNDHAKKPIRIIDLNLCQQVD 69 Query: 297 GA----EDVLNRKFAFELSTPGETMYFVADSDKEKEDWINSI 410 + + F+++T Y VADS+++ W+ I Sbjct: 70 AGLTFNKKEFENSYIFDINTIDRIFYLVADSEEDMNKWVRCI 111
>Q99PF6:GAB1_MESAU GRB2-associated-binding protein 1 - Mesocricetus auratus (Golden| hamster) Length = 694 Score = 43.5 bits (101), Expect = 0.001 Identities = 29/102 (28%), Positives = 43/102 (42%), Gaps = 12/102 (11%) Frame = +3 Query: 141 GWLDKQGEYIK----TWRRRWFVLKQGKLFWFKDSTV----TRASVPRGVIAVASCLTVK 296 GWL K K W+RRWFVL+ G+L D A P +I + C V Sbjct: 10 GWLRKSPPEKKLKRYAWKRRWFVLRSGRLTGDPDVLEYYKNDHAKKPIRIIDLNLCQQVD 69 Query: 297 GA----EDVLNRKFAFELSTPGETMYFVADSDKEKEDWINSI 410 + + F+++T Y VADS+++ W+ I Sbjct: 70 AGLTFNKKEFENSYIFDINTIDRIFYLVADSEEDMNKWVRCI 111
>Q8WZ64:CEND1_HUMAN Centaurin-delta 1 - Homo sapiens (Human)| Length = 1704 Score = 43.5 bits (101), Expect = 0.001 Identities = 29/112 (25%), Positives = 57/112 (50%) Frame = +3 Query: 129 PERGGWLDKQGEYIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAED 308 PE+ G+L+ +G ++ + F + G W + S I + VK + Sbjct: 588 PEKCGYLELRG-----YKAKIFTVLSGNSVWLCKNEQDFKSGLGITIIPMNVANVKQVDR 642 Query: 309 VLNRKFAFELSTPGETMYFVADSDKEKEDWINSIGRSIVQHSRSMTDDEIVD 464 + K +FE+ TP + F A+++KEK+DWI ++ +SI + +++D E+ + Sbjct: 643 TV--KQSFEIITPYRSFSFTAETEKEKQDWIEAVQQSIAE---TLSDYEVAE 689 Score = 36.6 bits (83), Expect = 0.12 Identities = 26/112 (23%), Positives = 55/112 (49%), Gaps = 3/112 (2%) Frame = +3 Query: 135 RGGWLDK---QGEYIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAE 305 + GWLDK QG+ + +++RW + ++ + + +G+I +++ TV+ Sbjct: 485 KSGWLDKLSPQGK--RMFQKRWVKFDGLSISYYNNE---KEMYSKGIIPLSAISTVRVQG 539 Query: 306 DVLNRKFAFELSTPGETMYFVADSDKEKEDWINSIGRSIVQHSRSMTDDEIV 461 D N+ FE+ T T F + ++E+ DWI+ + ++ S + +V Sbjct: 540 D--NK---FEVVTTQRTFVFRVEKEEERNDWISILLNALKSQSLTSQSQAVV 586
>Q63484:AKT3_RAT RAC-gamma serine/threonine-protein kinase - Rattus norvegicus (Rat)| Length = 479 Score = 43.1 bits (100), Expect = 0.001 Identities = 29/93 (31%), Positives = 45/93 (48%), Gaps = 4/93 (4%) Frame = +3 Query: 144 WLDKQGEYIKTWRRRWFVLK-QGKLFWFKDSTV-TRASVPRGVIAVASCLTVKGAEDVLN 317 W+ K+GEYIK WR R+F+LK G +K+ P +VA C +K N Sbjct: 11 WVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDLPYPLNNFSVAKCQLMKTERPKPN 70 Query: 318 RKF--AFELSTPGETMYFVADSDKEKEDWINSI 410 + +T E + V D+ +E+E+W +I Sbjct: 71 TFIIRCLQWTTVIERTFHV-DTPEEREEWTEAI 102
>Q4KM33:PLEK_RAT Pleckstrin - Rattus norvegicus (Rat)| Length = 350 Score = 42.4 bits (98), Expect = 0.002 Identities = 24/97 (24%), Positives = 47/97 (48%), Gaps = 1/97 (1%) Frame = +3 Query: 135 RGGWLDKQGEYIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVL 314 R G+L K+G TW+ W VL + + ++K + P+G+I + +D Sbjct: 7 REGYLVKKGSVFNTWKPMWVVLLEDGIEFYKKKSDNN---PKGMIPLKGSTLTSPCQDFG 63 Query: 315 NRKFAFEL-STPGETMYFVADSDKEKEDWINSIGRSI 422 R F ++ +T + +F A +E++ W+ I ++I Sbjct: 64 KRMFVLKITTTKQQDHFFQAAYLEERDAWVRDIKKAI 100 Score = 33.9 bits (76), Expect = 0.81 Identities = 26/95 (27%), Positives = 42/95 (44%), Gaps = 5/95 (5%) Frame = +3 Query: 141 GWLDKQGEYIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNR 320 G L KQG K W+ R F+L++ + P G I + C+ + + Sbjct: 249 GCLLKQGHRRKNWKVRKFILREDPAY-LHYYDPAGGEDPLGAIHLRGCVVTSVESNPDGK 307 Query: 321 KF----AFELSTPGETMYFV-ADSDKEKEDWINSI 410 K FE+ T E Y++ A + KE+ +WI +I Sbjct: 308 KSDEENLFEIITADEVHYYMQAATAKERTEWIKAI 342
>Q9JHK5:PLEK_MOUSE Pleckstrin - Mus musculus (Mouse)| Length = 350 Score = 42.4 bits (98), Expect = 0.002 Identities = 24/97 (24%), Positives = 48/97 (49%), Gaps = 1/97 (1%) Frame = +3 Query: 135 RGGWLDKQGEYIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVL 314 R G+L K+G TW+ W VL + + ++K + + P+G+I + +D Sbjct: 7 REGYLVKKGSVFNTWKPMWVVLLEDGIEFYKKKS---DNSPKGMIPLKGSTLTSPCQDFG 63 Query: 315 NRKFAFEL-STPGETMYFVADSDKEKEDWINSIGRSI 422 R F ++ +T + +F A +E++ W+ I ++I Sbjct: 64 KRMFVLKITTTKQQDHFFQAAFLEERDAWVRDIKKAI 100 Score = 37.7 bits (86), Expect = 0.056 Identities = 32/115 (27%), Positives = 55/115 (47%), Gaps = 10/115 (8%) Frame = +3 Query: 96 DATDGIEFWREPERG-----GWLDKQGEYIKTWRRRWFVLKQGKLFWFKDSTVTRASVPR 260 +++D RE RG G L KQG K W+ R F+L++ + P Sbjct: 229 NSSDDDVILREEFRGVIIKQGCLLKQGHRRKNWKVRKFILREDPAY-LHYYDPAGGEDPL 287 Query: 261 GVIAVASCL--TVKGAEDV--LNRKFAFELSTPGETMYFV-ADSDKEKEDWINSI 410 G + + C+ +V+ + DV + + FE+ T E Y++ A + KE+ +WI +I Sbjct: 288 GAVHLRGCVVTSVESSHDVKKSDEENLFEIITADEVHYYLQAATSKERTEWIKAI 342
>Q14B98:F109B_MOUSE Protein FAM109B - Mus musculus (Mouse)| Length = 259 Score = 42.4 bits (98), Expect = 0.002 Identities = 41/131 (31%), Positives = 60/131 (45%), Gaps = 4/131 (3%) Frame = +3 Query: 57 RAVMGTGAPSASADATDGIEFWREPERGGWLDKQGEYIKTWRRRWFVLKQGKLFWFKDST 236 R+V + AD T + W P G G T RR WFVLK LF F+ Sbjct: 6 RSVAHYALSDSPADHTGFLRSWGGP--GSPPTPSG----TGRRYWFVLKGNLLFSFE--- 56 Query: 237 VTRAS-VPRGVIAVASCLTVKGAEDVLNRKFAFEL--STPGETMYFV-ADSDKEKEDWIN 404 TR S VP ++ + C TV+ AE + +FAF + PG + + AD +E W+ Sbjct: 57 -TRESRVPLSLVVLEGC-TVELAEAPVPEEFAFAIRFDAPGVRPHLLAADGQAAQEAWVK 114 Query: 405 SIGRSIVQHSR 437 ++ R+ + R Sbjct: 115 ALSRASFGYMR 125
>Q9BZ29:DOCK9_HUMAN Dedicator of cytokinesis protein 9 - Homo sapiens (Human)| Length = 2069 Score = 42.4 bits (98), Expect = 0.002 Identities = 29/89 (32%), Positives = 51/89 (57%), Gaps = 6/89 (6%) Frame = +3 Query: 168 IKTWRRRWFVLKQ-----GKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAF 332 +++++RR+F L Q L ++KD +++ P+G I + SC+ V V R+FAF Sbjct: 194 MRSFKRRFFHLIQLGDGSYNLNFYKDEKISKE--PKGSIFLDSCMGVVQNNKV--RRFAF 249 Query: 333 ELSTPGETMYFV-ADSDKEKEDWINSIGR 416 EL ++ Y + ADS+ E E+WI + + Sbjct: 250 ELKMQDKSSYLLAADSEVEMEEWITILNK 278
>Q15027:CENB1_HUMAN Centaurin-beta 1 - Homo sapiens (Human)| Length = 740 Score = 42.4 bits (98), Expect = 0.002 Identities = 33/113 (29%), Positives = 53/113 (46%), Gaps = 6/113 (5%) Frame = +3 Query: 171 KTWRRRWFVLKQGKLFW---FKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELS 341 KTW RRWF ++ +L + +KD V+ TVK D R+F FE+ Sbjct: 281 KTWSRRWFTIQSNQLVYQKKYKDPVTV-------VVDDLRLCTVKLCPD-SERRFCFEVV 332 Query: 342 TPGETMYFVADSDKEKEDWINSIGRSIVQ-HSRSMTDDEI--VDYDSGHPATG 491 + ++ ADS++ + W++++ SI S++ DD SGH A G Sbjct: 333 STSKSCLLQADSERLLQLWVSAVQSSIASAFSQARLDDSPRGPGQGSGHLAIG 385
>P34512:GRP1_CAEEL GTP exchange factor for ARFs 1 - Caenorhabditis elegans| Length = 393 Score = 42.0 bits (97), Expect = 0.003 Identities = 33/120 (27%), Positives = 55/120 (45%), Gaps = 25/120 (20%) Frame = +3 Query: 132 ERGGWLDKQGEY-----IKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVK 296 ER GWL KQ +W++RWFVL + L++F T P+G+I +A+ K Sbjct: 263 EREGWLFKQSSNPLFSGALSWKKRWFVLSENCLYYFDQMT---DKEPKGIITLANVGIRK 319 Query: 297 GAEDVLNRKFAFELSTPGE-------------------TMYFV-ADSDKEKEDWINSIGR 416 + +R F FE+ + + ++Y + A +D++ WIN+I R Sbjct: 320 --VEAPSRPFMFEIFSLSDGQIKACKTEQDGRLVEGRHSIYKICAVNDEDMRSWINAISR 377
>Q2WGN9:GAB4_HUMAN GRB2-associated-binding protein 4 - Homo sapiens (Human)| Length = 574 Score = 42.0 bits (97), Expect = 0.003 Identities = 27/107 (25%), Positives = 51/107 (47%), Gaps = 17/107 (15%) Frame = +3 Query: 141 GWLDKQGEYIK----TWRRRWFVLKQGK-------LFWFKDSTVTRASVPRGVIAVASC- 284 GWL K K WR+RWF+L++G+ L ++K+ + P I + C Sbjct: 44 GWLRKSPPEKKLRLFAWRKRWFILRRGQTSSDPDVLEYYKNDGSKK---PLRTINLNLCE 100 Query: 285 -----LTVKGAEDVLNRKFAFELSTPGETMYFVADSDKEKEDWINSI 410 +T+ + + + + F++ T T Y VA++ ++ +W+ SI Sbjct: 101 QLDVDVTLNFNKKEIQKGYMFDIKTSERTFYLVAETREDMNEWVQSI 147
>Q9EQG9:C43BP_MOUSE Goodpasture antigen-binding protein - Mus musculus (Mouse)| Length = 624 Score = 42.0 bits (97), Expect = 0.003 Identities = 26/93 (27%), Positives = 41/93 (44%) Frame = +3 Query: 132 ERGGWLDKQGEYIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDV 311 ER G L K YI W+ RW VLK L ++K T RG I ++ + D Sbjct: 25 ERCGVLSKWTNYIHGWQDRWVVLKNNTLSYYKSEDETEYGC-RGSICLSKAVITPHDFD- 82 Query: 312 LNRKFAFELSTPGETMYFVADSDKEKEDWINSI 410 + F++S Y A + ++ W+++I Sbjct: 83 ---ECRFDISVNDSVWYLRAQDPEHRQQWVDAI 112
>Q8BIK4:DOCK9_MOUSE Dedicator of cytokinesis protein 9 - Mus musculus (Mouse)| Length = 2055 Score = 41.6 bits (96), Expect = 0.004 Identities = 28/89 (31%), Positives = 51/89 (57%), Gaps = 6/89 (6%) Frame = +3 Query: 168 IKTWRRRWFVLKQ-----GKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAF 332 +++++RR+F L Q L ++KD +++ P+G I + SC+ V V R+FAF Sbjct: 205 MRSFKRRFFHLIQLGDGSYNLNFYKDEKISKE--PKGSIFLDSCMGVIQNNRV--RRFAF 260 Query: 333 ELSTPGETMYFV-ADSDKEKEDWINSIGR 416 EL ++ Y + ADS+ E E+W+ + + Sbjct: 261 ELKMQDKSSYLLAADSEAEMEEWVTVLNK 289
>Q96P48:CEND2_HUMAN Centaurin-delta 2 - Homo sapiens (Human)| Length = 1210 Score = 41.6 bits (96), Expect = 0.004 Identities = 34/121 (28%), Positives = 56/121 (46%), Gaps = 3/121 (2%) Frame = +3 Query: 75 GAPSASADATDGIEFWREPERGGWLDK---QGEYIKTWRRRWFVLKQGKLFWFKDSTVTR 245 G P S T I + GWLDK QG YI +++RW L L +F + + Sbjct: 77 GPPGGSTPVTPVI-------KAGWLDKNPPQGSYI--YQKRWVRLDTDHLRYFDSN---K 124 Query: 246 ASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPGETMYFVADSDKEKEDWINSIGRSIV 425 + + I+VA V D FE+ T T F A+SD E+++W+ ++ +++ Sbjct: 125 DAYSKRFISVACISHVAAIGDQ-----KFEVITNNRTFAFRAESDVERKEWMQALQQAMA 179 Query: 426 Q 428 + Sbjct: 180 E 180 Score = 32.3 bits (72), Expect = 2.4 Identities = 27/108 (25%), Positives = 55/108 (50%), Gaps = 1/108 (0%) Frame = +3 Query: 108 GIEFWREPERGGWLDKQGEYIKTWRRRWFVLKQG-KLFWFKDSTVTRASVPRGVIAVASC 284 G+ +P+R G L+ +G ++ + +V G K+ +K+ + G+ + Sbjct: 194 GVPGSEQPDRAGSLELRG-----FKNKLYVAVVGDKVQLYKNLEEYHLGI--GITFID-- 244 Query: 285 LTVKGAEDVLNRKFAFELSTPGETMYFVADSDKEKEDWINSIGRSIVQ 428 ++V ++V R +F+L+TP F ADS+ EKE W+ ++ +I + Sbjct: 245 MSVGNVKEVDRR--SFDLTTPYRIFSFSADSELEKEQWLEAMQGAIAE 290
>Q5R6M6:C43BP_PONPY Goodpasture antigen-binding protein - Pongo pygmaeus (Orangutan)| Length = 624 Score = 41.6 bits (96), Expect = 0.004 Identities = 27/93 (29%), Positives = 40/93 (43%) Frame = +3 Query: 132 ERGGWLDKQGEYIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDV 311 ER G L K YI W+ RW VLK L ++K T RG I ++ + D Sbjct: 25 ERCGVLSKWTNYIHGWQDRWVVLKNNALSYYKSEDETEYGC-RGSICLSKAVITPHDFD- 82 Query: 312 LNRKFAFELSTPGETMYFVADSDKEKEDWINSI 410 + F++S Y A ++ WI++I Sbjct: 83 ---ECRFDISVNDSVWYLRAQDPDHRQQWIDAI 112
>Q9Y5P4:C43BP_HUMAN Goodpasture antigen-binding protein - Homo sapiens (Human)| Length = 624 Score = 41.6 bits (96), Expect = 0.004 Identities = 27/93 (29%), Positives = 40/93 (43%) Frame = +3 Query: 132 ERGGWLDKQGEYIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDV 311 ER G L K YI W+ RW VLK L ++K T RG I ++ + D Sbjct: 25 ERCGVLSKWTNYIHGWQDRWVVLKNNALSYYKSEDETEYGC-RGSICLSKAVITPHDFD- 82 Query: 312 LNRKFAFELSTPGETMYFVADSDKEKEDWINSI 410 + F++S Y A ++ WI++I Sbjct: 83 ---ECRFDISVNDSVWYLRAQDPDHRQQWIDAI 112
>Q9GKI7:C43BP_BOVIN Goodpasture antigen-binding protein - Bos taurus (Bovine)| Length = 624 Score = 41.6 bits (96), Expect = 0.004 Identities = 27/93 (29%), Positives = 40/93 (43%) Frame = +3 Query: 132 ERGGWLDKQGEYIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDV 311 ER G L K YI W+ RW VLK L ++K T RG I ++ + D Sbjct: 25 ERCGVLSKWTNYIHGWQDRWVVLKNNTLSYYKSEDETEYGC-RGSICLSKAVITPHDFD- 82 Query: 312 LNRKFAFELSTPGETMYFVADSDKEKEDWINSI 410 + F++S Y A ++ WI++I Sbjct: 83 ---ECRFDISVNDSVWYLRAQDPDHRQQWIDAI 112
>Q969R2:OSBP2_HUMAN Oxysterol-binding protein 2 - Homo sapiens (Human)| Length = 916 Score = 41.2 bits (95), Expect = 0.005 Identities = 36/143 (25%), Positives = 70/143 (48%), Gaps = 4/143 (2%) Frame = +3 Query: 69 GTGAPSASADATDGIEFWREPERGGWLDKQGEYIKTWRRRWFVLKQGKLFWFKDSTVTRA 248 GTG S++ A ++ + GWL K Y+K ++RRWFVL G L ++++ A Sbjct: 168 GTGTTSSAPLALLPLDSFE-----GWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQG-EMA 221 Query: 249 SVPRGVIAVASC-LTVKGAEDVLNRKFAFELSTPGETMYFVADSDKEKEDWINSIGRSIV 425 RG I +++ + + + +L L++ + + A S+ +++ WI ++ + Sbjct: 222 HTCRGTINLSTAHIDTEDSCGIL-------LTSGARSYHLKASSEVDRQQWITALELAKA 274 Query: 426 QHSRSM---TDDEIVDYDSGHPA 485 + R M +DD D ++ PA Sbjct: 275 KAVRVMNTHSDDSGDDDEATTPA 297
>Q64398:DGKH_MESAU Diacylglycerol kinase eta - Mesocricetus auratus (Golden hamster)| Length = 1154 Score = 41.2 bits (95), Expect = 0.005 Identities = 28/91 (30%), Positives = 45/91 (49%), Gaps = 1/91 (1%) Frame = +3 Query: 141 GWLDKQGEYIKTWRRRWFVLKQGKLFWFKDS-TVTRASVPRGVIAVASCLTVKGAEDVLN 317 G L KQ + W++R+F L+ L++ KDS ++ V +VA T N Sbjct: 64 GQLLKQTSSFQRWKKRYFKLRGRTLYYAKDSKSLIFDEVDLSDASVAEAST-------KN 116 Query: 318 RKFAFELSTPGETMYFVADSDKEKEDWINSI 410 +F + TP + A++ KE EDWI+S+ Sbjct: 117 ANNSFTIITPFRRLMLCAENRKEMEDWISSL 147
>Q86XP1:DGKH_HUMAN Diacylglycerol kinase eta - Homo sapiens (Human)| Length = 1220 Score = 41.2 bits (95), Expect = 0.005 Identities = 28/91 (30%), Positives = 45/91 (49%), Gaps = 1/91 (1%) Frame = +3 Query: 141 GWLDKQGEYIKTWRRRWFVLKQGKLFWFKDS-TVTRASVPRGVIAVASCLTVKGAEDVLN 317 G L KQ + W++R+F L+ L++ KDS ++ V +VA T N Sbjct: 70 GQLLKQTSSFQRWKKRYFKLRGRTLYYAKDSKSLIFDEVDLSDASVAEAST-------KN 122 Query: 318 RKFAFELSTPGETMYFVADSDKEKEDWINSI 410 +F + TP + A++ KE EDWI+S+ Sbjct: 123 ANNSFTIITPFRRLMLCAENRKEMEDWISSL 153
>P39969:BOI2_YEAST Protein BOI2 - Saccharomyces cerevisiae (Baker's yeast)| Length = 1040 Score = 41.2 bits (95), Expect = 0.005 Identities = 31/133 (23%), Positives = 57/133 (42%), Gaps = 23/133 (17%) Frame = +3 Query: 114 EFWREPERGGWLDKQGE-YIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLT 290 E ++ + GW+ K+G + TW+ R+F L +L +F +T TR RG+I + + Sbjct: 764 EAMKDADFSGWMSKKGSGAMSTWKTRFFTLHGTRLSYFSSTTDTR---ERGLIDITAHRV 820 Query: 291 VKGAED----------VLNRKFAFELSTP------------GETMYFVADSDKEKEDWIN 404 V ED ++ F+L P T YF D+ +E W+ Sbjct: 821 VPAKEDDKLVSLYAASTGKGRYCFKLLPPQPGSKKGLTFTQPRTHYFAVDNKEEMRGWMA 880 Query: 405 SIGRSIVQHSRSM 443 ++ ++ + S+ Sbjct: 881 ALIKTTIDIDTSV 893
>Q6A028:SWP70_MOUSE Switch-associated protein 70 - Mus musculus (Mouse)| Length = 585 Score = 40.8 bits (94), Expect = 0.007 Identities = 25/94 (26%), Positives = 43/94 (45%) Frame = +3 Query: 141 GWLDKQGEYIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNR 320 G++ K+G K W RWFVLK + ++ + +G I + V+ D + Sbjct: 215 GYMMKKGHKRKNWTERWFVLKPNIISYYVSEDL---KDKKGDILLDENCCVESLPDKDGK 271 Query: 321 KFAFELSTPGETMYFVADSDKEKEDWINSIGRSI 422 K F + +T A K+K++WI +I +I Sbjct: 272 KCLFLIKCFDKTFEISASDKKKKQEWIQAIYSTI 305
>Q9UH65:SWP70_HUMAN Switch-associated protein 70 - Homo sapiens (Human)| Length = 585 Score = 40.8 bits (94), Expect = 0.007 Identities = 25/94 (26%), Positives = 43/94 (45%) Frame = +3 Query: 141 GWLDKQGEYIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNR 320 G++ K+G K W RWFVLK + ++ + +G I + V+ D + Sbjct: 215 GYMMKKGHRRKNWTERWFVLKPNIISYYVSEDL---KDKKGDILLDENCCVESLPDKDGK 271 Query: 321 KFAFELSTPGETMYFVADSDKEKEDWINSIGRSI 422 K F + +T A K+K++WI +I +I Sbjct: 272 KCLFLVKCFDKTFEISASDKKKKQEWIQAIHSTI 305
>Q86SQ0:PHLB2_HUMAN Pleckstrin homology-like domain family B member 2 - Homo sapiens| (Human) Length = 1253 Score = 40.8 bits (94), Expect = 0.007 Identities = 30/97 (30%), Positives = 43/97 (44%), Gaps = 7/97 (7%) Frame = +3 Query: 141 GWLDKQGEYIKTWRRRWFVLKQGK--LFWFKDSTVTRASVPRGVIAVASCLTV-----KG 299 G+L K G IKTW++RWFV + K ++ D T+ +GVI + V K Sbjct: 1148 GFLIKMGGKIKTWKKRWFVFDRNKRTFSYYADKHETKL---KGVIYFQAIEEVYYDHLKN 1204 Query: 300 AEDVLNRKFAFELSTPGETMYFVADSDKEKEDWINSI 410 A N F + T Y VA S + W++ I Sbjct: 1205 ANKSPNPLLTFSVKTHDRIYYMVAPSPEAMRIWMDVI 1241
>O95248:MTMR5_HUMAN Myotubularin-related protein 5 - Homo sapiens (Human)| Length = 1866 Score = 40.8 bits (94), Expect = 0.007 Identities = 29/98 (29%), Positives = 44/98 (44%), Gaps = 8/98 (8%) Frame = +3 Query: 141 GWLDKQGEYIKTWRRRWFVLKQGK--LFWFKDSTVTRASVPRGVI------AVASCLTVK 296 G L K+G ++K W+ RWFVL + K L ++ T +GVI AVA Sbjct: 1765 GTLYKKGAFMKPWKARWFVLDKTKHQLRYYDHRVDTEC---KGVIDLAEVEAVAPGTPTM 1821 Query: 297 GAEDVLNRKFAFELSTPGETMYFVADSDKEKEDWINSI 410 GA ++ K F++ T F A + W++ I Sbjct: 1822 GAPKTVDEKAFFDVKTTRRVYNFCAQDVPSAQQWVDRI 1859
>P0C1G6:SWP70_BOVIN Switch-associated protein 70 - Bos taurus (Bovine)| Length = 585 Score = 40.4 bits (93), Expect = 0.009 Identities = 25/94 (26%), Positives = 43/94 (45%) Frame = +3 Query: 141 GWLDKQGEYIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNR 320 G++ K+G K W RWFVLK + ++ + +G I + V+ D + Sbjct: 215 GYMIKKGHRRKNWTERWFVLKPHIISYYVSEDL---KDKKGDILLDENCCVESLPDKDGK 271 Query: 321 KFAFELSTPGETMYFVADSDKEKEDWINSIGRSI 422 K F + +T A K+K++WI +I +I Sbjct: 272 KCLFLIKCFDKTFEISASDKKKKQEWIQAIHSTI 305
>Q9HB20:PKHA3_HUMAN Pleckstrin homology domain-containing family A member 3 - Homo| sapiens (Human) Length = 300 Score = 40.4 bits (93), Expect = 0.009 Identities = 31/95 (32%), Positives = 46/95 (48%), Gaps = 2/95 (2%) Frame = +3 Query: 141 GWLDKQGEYIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASC-LTVKGAEDVLN 317 G L K Y+ W+ RWFVL G L ++ DS +G I +A C + V A++ Sbjct: 3 GVLYKWTNYLTGWQPRWFVLDNGILSYY-DSQDDVCKGSKGSIKMAVCEIKVHSADNT-- 59 Query: 318 RKFAFELSTPGET-MYFVADSDKEKEDWINSIGRS 419 EL PGE Y A + E++ W+ ++G S Sbjct: 60 ---RMELIIPGEQHFYMKAVNAAERQRWLVALGSS 91
>Q8WQ85:VILD_DICDI Villidin - Dictyostelium discoideum (Slime mold)| Length = 1704 Score = 40.0 bits (92), Expect = 0.011 Identities = 20/102 (19%), Positives = 55/102 (53%), Gaps = 10/102 (9%) Frame = +3 Query: 186 RWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLN-RKFAFELSTPGETMY 362 +W+V+ +G L+ +K+ ++ + P I + ++ +++ + F+F+LSTP ++ Sbjct: 749 KWYVVSEGMLYSYKNKSLKQLD-PLETIHLEKAISAHKTKEIFTIQGFSFQLSTPNRIIH 807 Query: 363 FVADSDKEKEDWINSIGRSIVQH---------SRSMTDDEIV 461 +A + +E+ W++ + +++ +R+ T DE++ Sbjct: 808 LLAKTKEERGSWLSVLRQNLKSSGETKPKSVLTRASTMDELI 849
>P09851:RASA1_BOVIN Ras GTPase-activating protein 1 - Bos taurus (Bovine)| Length = 1044 Score = 40.0 bits (92), Expect = 0.011 Identities = 30/124 (24%), Positives = 58/124 (46%), Gaps = 19/124 (15%) Frame = +3 Query: 96 DATDGIE------------FWREPERGGWLDKQGEYIKTWRRRWFVLK--QGKLFWFKDS 233 DA DG E F++ + G+L K+G+ K W+ +F+L+ +L +F+ Sbjct: 449 DAVDGKEIYNTIRRKTKDAFYKNIVKKGYLLKKGKG-KRWKNLYFILEGSDAQLIYFESE 507 Query: 234 TVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFEL-----STPGETMYFVADSDKEKEDW 398 RA+ P+G+I ++ C + + R F++ S YF ++ ++ EDW Sbjct: 508 K--RATKPKGLIDLSVCSVYVVHDSLFGRPNCFQIVVQHFSEEHYIFYFAGETPEQAEDW 565 Query: 399 INSI 410 + + Sbjct: 566 MKGL 569
>Q96SU4:OSBL9_HUMAN Oxysterol-binding protein-related protein 9 - Homo sapiens (Human)| Length = 736 Score = 40.0 bits (92), Expect = 0.011 Identities = 26/100 (26%), Positives = 45/100 (45%), Gaps = 2/100 (2%) Frame = +3 Query: 141 GWLDKQGEYIKTWRRRWFVL--KQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVL 314 G L K +K W+ RWFVL G L ++ RG + + + ED Sbjct: 7 GPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDED-- 64 Query: 315 NRKFAFELSTPGETMYFVADSDKEKEDWINSIGRSIVQHS 434 F ++ +T +F A E+E WI+++ +I++H+ Sbjct: 65 --DSTFTITVDQKTFHFQARDADEREKWIHALEETILRHT 102
>Q969H4:CNKR1_HUMAN Connector enhancer of kinase suppressor of ras 1 - Homo sapiens| (Human) Length = 720 Score = 40.0 bits (92), Expect = 0.011 Identities = 28/99 (28%), Positives = 48/99 (48%), Gaps = 5/99 (5%) Frame = +3 Query: 129 PERGGWL---DKQGEYI-KTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVK 296 P+ GWL G ++ WRRRWFVLK L+W++ +A G+I V++ Sbjct: 404 PDCDGWLLLRKAPGGFMGPRWRRRWFVLKGHTLYWYRQPQDEKA---EGLINVSNYSLES 460 Query: 297 GAEDVLNRKFAFELS-TPGETMYFVADSDKEKEDWINSI 410 G + +K+ F+L+ + F AD+ + W+ + Sbjct: 461 GHDQ--KKKYVFQLTHDVYKPFIFAADTLTDLSMWVRHL 497
>P50904:RASA1_RAT Ras GTPase-activating protein 1 - Rattus norvegicus (Rat)| Length = 1038 Score = 39.7 bits (91), Expect = 0.015 Identities = 25/105 (23%), Positives = 53/105 (50%), Gaps = 7/105 (6%) Frame = +3 Query: 117 FWREPERGGWLDKQGEYIKTWRRRWFVLK--QGKLFWFKDSTVTRASVPRGVIAVASCLT 290 F++ + G+L K+G+ K W+ +F+L+ +L +F+ RA+ P+G+I ++ C Sbjct: 462 FYKNIVKKGYLLKKGKG-KRWKNLYFILEGSDAQLIYFESEK--RATKPKGLIDLSVCSV 518 Query: 291 VKGAEDVLNRKFAFEL-----STPGETMYFVADSDKEKEDWINSI 410 + + R F++ S YF ++ ++ EDW+ + Sbjct: 519 YVVHDSLFGRPNCFQIVVQHFSEEHYIFYFAGETPEQAEDWMKGL 563
>P20936:RASA1_HUMAN Ras GTPase-activating protein 1 - Homo sapiens (Human)| Length = 1047 Score = 39.7 bits (91), Expect = 0.015 Identities = 25/105 (23%), Positives = 53/105 (50%), Gaps = 7/105 (6%) Frame = +3 Query: 117 FWREPERGGWLDKQGEYIKTWRRRWFVLK--QGKLFWFKDSTVTRASVPRGVIAVASCLT 290 F++ + G+L K+G+ K W+ +F+L+ +L +F+ RA+ P+G+I ++ C Sbjct: 471 FYKNIVKKGYLLKKGKG-KRWKNLYFILEGSDAQLIYFESEK--RATKPKGLIDLSVCSV 527 Query: 291 VKGAEDVLNRKFAFEL-----STPGETMYFVADSDKEKEDWINSI 410 + + R F++ S YF ++ ++ EDW+ + Sbjct: 528 YVVHDSLFGRPNCFQIVVQHFSEEHYIFYFAGETPEQAEDWMKGL 572
>Q9ERS4:PKHA3_MOUSE Pleckstrin homology domain-containing family A member 3 - Mus| musculus (Mouse) Length = 297 Score = 39.7 bits (91), Expect = 0.015 Identities = 31/95 (32%), Positives = 46/95 (48%), Gaps = 2/95 (2%) Frame = +3 Query: 141 GWLDKQGEYIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASC-LTVKGAEDVLN 317 G L K Y+ W+ RWFVL G L ++ DS +G I +A C + V A++ Sbjct: 3 GVLYKWTNYLTGWQPRWFVLDNGILSYY-DSQDDVCKGSKGSIKMAVCEIKVHPADNT-- 59 Query: 318 RKFAFELSTPGET-MYFVADSDKEKEDWINSIGRS 419 EL PGE Y A + E++ W+ ++G S Sbjct: 60 ---RMELIIPGEQHFYMKAVNAAERQRWLVALGSS 91
>Q8K1N2:PHLB2_MOUSE Pleckstrin homology-like domain family B member 2 - Mus musculus| (Mouse) Length = 1249 Score = 39.7 bits (91), Expect = 0.015 Identities = 29/95 (30%), Positives = 42/95 (44%), Gaps = 5/95 (5%) Frame = +3 Query: 141 GWLDKQGEYIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTV-----KGAE 305 G+L K G IKTW++RWFV + K + + A + +GVI + V K A Sbjct: 1144 GYLIKMGGKIKTWKKRWFVFDRNKRTFSYYADKHEAKL-KGVIYFQAIEEVYYDHLKNAN 1202 Query: 306 DVLNRKFAFELSTPGETMYFVADSDKEKEDWINSI 410 N F + T Y VA S + W++ I Sbjct: 1203 KSPNPLLTFSVKTHDRIYYMVAPSPEAMRIWMDVI 1237
>Q5QNQ6:OSBP2_MOUSE Oxysterol-binding protein 2 - Mus musculus (Mouse)| Length = 908 Score = 39.7 bits (91), Expect = 0.015 Identities = 28/90 (31%), Positives = 43/90 (47%) Frame = +3 Query: 141 GWLDKQGEYIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNR 320 GWL K Y+K ++RRWFVL G L ++++ A R I +AS T ED Sbjct: 184 GWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQG-EMAHTCRATINLAS--THFETED---- 236 Query: 321 KFAFELSTPGETMYFVADSDKEKEDWINSI 410 L T + A S+ +++ WI ++ Sbjct: 237 SCGILLCNGARTYHLKASSEVDRQHWITAL 266
>Q8C2K1:DEFI6_MOUSE Differentially expressed in FDCP 6 - Mus musculus (Mouse)| Length = 630 Score = 39.7 bits (91), Expect = 0.015 Identities = 29/123 (23%), Positives = 52/123 (42%), Gaps = 1/123 (0%) Frame = +3 Query: 57 RAVMGTGAPSASADATDGI-EFWREPERGGWLDKQGEYIKTWRRRWFVLKQGKLFWFKDS 233 R + G G S S + E ++ + G+L K+G + W RWF L+ L +F Sbjct: 192 RCLRGVGRDSLSMAIQEVYQELIQDVLKQGYLWKRGHLRRNWAERWFQLQPSSLCYFGSE 251 Query: 234 TVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPGETMYFVADSDKEKEDWINSIG 413 RG I + + V+ D ++ F + T T A +++++W +I Sbjct: 252 ---ECKEKRGTIPLDAHCCVEVLPDREGKRCMFCVKTASRTYEMSASDTRQRQEWTAAIQ 308 Query: 414 RSI 422 +I Sbjct: 309 TAI 311
>Q7S1I0:ATG26_NEUCR Sterol 3-beta-glucosyltransferase - Neurospora crassa| Length = 1553 Score = 39.7 bits (91), Expect = 0.015 Identities = 32/112 (28%), Positives = 50/112 (44%) Frame = +3 Query: 126 EPERGGWLDKQGEYIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAE 305 E + G+L K G+ + R WF LK L +++D P G I + ++ Sbjct: 374 EIAKSGYLSKSGKRNPKYNRYWFRLKGDVLSYYQDPK--DHYFPAGQIDLRYGISAS-VN 430 Query: 306 DVLNRKFAFELSTPGETMYFVADSDKEKEDWINSIGRSIVQHSRSMTDDEIV 461 D F +ST T +F ADS + ++W+ S+ R I RS D + V Sbjct: 431 DKEKEGNYFSVSTHHRTYHFKADSARSAKEWVKSLQRVIF---RSHNDGDSV 479
>Q5B4C9:ATG26_EMENI Sterol 3-beta-glucosyltransferase - Emericella nidulans| (Aspergillus nidulans) Length = 1396 Score = 39.7 bits (91), Expect = 0.015 Identities = 25/98 (25%), Positives = 46/98 (46%), Gaps = 2/98 (2%) Frame = +3 Query: 135 RGGWLDKQGEYIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAE--D 308 + G++ K+G + R WF LK+ L ++ D + P G I + ++ E D Sbjct: 292 KSGYIYKRGRKNPKYNRYWFSLKEDVLSYYADPS--NLYFPSGQIDLRYGISASLTEPKD 349 Query: 309 VLNRKFAFELSTPGETMYFVADSDKEKEDWINSIGRSI 422 F+++T T YF ADS ++W+ ++ + I Sbjct: 350 KSRESRDFQVTTDHRTYYFRADSSVNAKEWVRALQKVI 387
>Q9QWN8:SPTN2_RAT Spectrin beta chain, brain 2 - Rattus norvegicus (Rat)| Length = 2388 Score = 39.3 bits (90), Expect = 0.019 Identities = 26/98 (26%), Positives = 44/98 (44%), Gaps = 3/98 (3%) Frame = +3 Query: 171 KTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKG--AEDVLNRKFAFELS- 341 ++W+ + VL++G L ++KD+ A VP S +G A D RK F+L Sbjct: 2241 RSWQNVYCVLRRGSLGFYKDARAASAGVPYHGEVPVSLARAQGSVAFDYRKRKHVFKLGL 2300 Query: 342 TPGETMYFVADSDKEKEDWINSIGRSIVQHSRSMTDDE 455 G+ F A + E W+ + +I S + + E Sbjct: 2301 QDGKEYLFQAKDEAEMSSWLRVVNAAIATASSASGEPE 2338
>O15020:SPTN2_HUMAN Spectrin beta chain, brain 2 - Homo sapiens (Human)| Length = 2390 Score = 39.3 bits (90), Expect = 0.019 Identities = 26/98 (26%), Positives = 44/98 (44%), Gaps = 3/98 (3%) Frame = +3 Query: 171 KTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKG--AEDVLNRKFAFELS- 341 ++W+ + VL++G L ++KD+ A VP S +G A D RK F+L Sbjct: 2241 RSWQNVYCVLRRGSLGFYKDAKAASAGVPYHGEVPVSLARAQGSVAFDYRKRKHVFKLGL 2300 Query: 342 TPGETMYFVADSDKEKEDWINSIGRSIVQHSRSMTDDE 455 G+ F A + E W+ + +I S + + E Sbjct: 2301 QDGKEYLFQAKDEAEMSSWLRVVNAAIATASSASGEPE 2338
>Q6ZPE2:MTMR5_MOUSE Myotubularin-related protein 5 - Mus musculus (Mouse)| Length = 1867 Score = 39.3 bits (90), Expect = 0.019 Identities = 29/98 (29%), Positives = 44/98 (44%), Gaps = 8/98 (8%) Frame = +3 Query: 141 GWLDKQGEYIKTWRRRWFVLKQGK--LFWFKDSTVTRASVPRGVI------AVASCLTVK 296 G L K+G ++K W+ RWFVL + K L ++ T +GVI AVA Sbjct: 1766 GILYKKGAFMKPWKARWFVLDKTKHQLRYYDHRMDTEC---KGVIDLAEVEAVAPGTPTI 1822 Query: 297 GAEDVLNRKFAFELSTPGETMYFVADSDKEKEDWINSI 410 GA ++ K F++ T F A + W++ I Sbjct: 1823 GAPKTVDEKAFFDVKTTRRVYNFCAQDVPSAQQWVDRI 1860
>Q7SYB5:DEFI6_DANRE Differentially expressed in FDCP 6 homolog - Danio rerio| (Zebrafish) (Brachydanio rerio) Length = 612 Score = 39.3 bits (90), Expect = 0.019 Identities = 25/94 (26%), Positives = 43/94 (45%) Frame = +3 Query: 141 GWLDKQGEYIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNR 320 G+L K+G+ + W RWF L+ L +F T +G I + V+ D + Sbjct: 216 GYLWKKGQLRRNWTERWFTLRPSTLLYF---TSEDRKDHKGNIQLDGNCCVEVLPDRDGK 272 Query: 321 KFAFELSTPGETMYFVADSDKEKEDWINSIGRSI 422 + F L T +T A K++++W +I +I Sbjct: 273 RCMFCLKTLTKTYELSASDTKQRQEWTTAIQTAI 306
>Q9UUE2:CSX2_SCHPO Protein csx2 - Schizosaccharomyces pombe (Fission yeast)| Length = 870 Score = 39.3 bits (90), Expect = 0.019 Identities = 32/101 (31%), Positives = 48/101 (47%), Gaps = 8/101 (7%) Frame = +3 Query: 177 WRRRWFVLKQGKLFWFKD--STVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPG 350 W + W VL GK+ + + ++ + P ++ TV+ A+ V +RKF FE+ TP Sbjct: 535 WHKYWVVLDHGKICEYANWKQSLELHTEPIDLLMA----TVRPAQSV-SRKFCFEVITPQ 589 Query: 351 ETMYFVADSDKEKEDWIN----SIGRSIVQHSR--SMTDDE 455 + A S E WI SI SIVQ + SM +E Sbjct: 590 TKRTYQATSKAEMHSWIEAIQYSISESIVQKGKGTSMNSEE 630
>Q9H254:SPTN4_HUMAN Spectrin beta chain, brain 3 - Homo sapiens (Human)| Length = 2564 Score = 38.9 bits (89), Expect = 0.025 Identities = 32/127 (25%), Positives = 55/127 (43%), Gaps = 7/127 (5%) Frame = +3 Query: 171 KTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASC--LTVKGAEDVLNRKFAFELST 344 ++W + VL +G+L ++KDS + G + S T + A D +K F+L T Sbjct: 2440 RSWVSLYCVLSKGELGFYKDSKGPASGSTHGGEPLLSLHKATSEVASDYKKKKHVFKLQT 2499 Query: 345 -PGETMYFVADSDKEKEDWINSIGRSIVQHSR----SMTDDEIVDYDSGHPATGRKS*VR 509 G A ++E W+ ++ S+ +H+ T D G+P R+ R Sbjct: 2500 QDGSEFLLQAKDEEEMNGWLEAVASSVAEHAEIARWGQTLPTTSSTDEGNPK--REGGDR 2557 Query: 510 RLIGEQK 530 R G +K Sbjct: 2558 RASGRRK 2564
>Q5F4B2:SWP70_CHICK Switch-associated protein 70 - Gallus gallus (Chicken)| Length = 586 Score = 38.5 bits (88), Expect = 0.033 Identities = 23/94 (24%), Positives = 43/94 (45%) Frame = +3 Query: 141 GWLDKQGEYIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNR 320 G++ K+G K W RWFVLK + ++ + +G I + V+ D + Sbjct: 215 GYMLKKGHKRKNWTERWFVLKPNIISYYVSEDL---KDKKGDIILDGNCCVEPLPDKDGK 271 Query: 321 KFAFELSTPGETMYFVADSDKEKEDWINSIGRSI 422 K F + ++ A K+K++WI +I ++ Sbjct: 272 KCLFLIKCLDKSFEISASDKKKKQEWIQAIQTTV 305
>P28818:GNRP_RAT Guanine nucleotide-releasing protein - Rattus norvegicus (Rat)| Length = 1244 Score = 38.5 bits (88), Expect = 0.033 Identities = 26/115 (22%), Positives = 49/115 (42%), Gaps = 11/115 (9%) Frame = +3 Query: 108 GIEFWREPERGGWLDKQGEYIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCL 287 G+ R+ R G+L K+ W+ +WF L Q LF+F+ + +R P G+ + + Sbjct: 16 GLLAQRDGTRKGYLSKRSSDNPKWQTKWFALLQNLLFYFESDSSSR---PSGLYLLEGSI 72 Query: 288 ----------TVKGAEDVLNRKFAFELSTPGE-TMYFVADSDKEKEDWINSIGRS 419 T D + F S + ++ D K+ ++W+ +I R+ Sbjct: 73 CKRMPSPKRGTSSKESDKQHHYFTVNFSNDSQKSLELRTDDSKDCDEWVAAIARA 127
>Q9H4E7:DEFI6_HUMAN Differentially expressed in FDCP 6 - Homo sapiens (Human)| Length = 631 Score = 38.1 bits (87), Expect = 0.043 Identities = 23/94 (24%), Positives = 42/94 (44%) Frame = +3 Query: 141 GWLDKQGEYIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNR 320 G+L K+G + W RWF L+ L +F RG+I + + V+ D + Sbjct: 221 GYLWKRGHLRRNWAERWFQLQPSCLCYFGSE---ECKEKRGIIPLDAHCCVEVLPDRDGK 277 Query: 321 KFAFELSTPGETMYFVADSDKEKEDWINSIGRSI 422 + F + T T A +++++W +I +I Sbjct: 278 RCMFCVKTANRTYEMSASDTRQRQEWTAAIQMAI 311
>Q12451:OSH2_YEAST Oxysterol-binding protein homolog 2 - Saccharomyces cerevisiae| (Baker's yeast) Length = 1283 Score = 37.7 bits (86), Expect = 0.056 Identities = 34/124 (27%), Positives = 56/124 (45%), Gaps = 4/124 (3%) Frame = +3 Query: 123 REPERGGWLDKQGEYIKTWRRRWFVLK-QGKLFWFKDSTVTRASVPRGVIAVASCLTVKG 299 + P G+L K + ++ RWF+L G L ++KD + PRG + V++C Sbjct: 288 KPPTYKGFLKKWTNFAHGYKLRWFILSGDGNLSYYKDQ--SHVDRPRGTLKVSTCRLHID 345 Query: 300 AEDVLNRKFAFEL--STPGETMYFVADSDK-EKEDWINSIGRSIVQHSRSMTDDEIVDYD 470 + + LN FEL G T + + + E W+N+I +I R D EI++ Sbjct: 346 SSEKLN----FELLGGITGTTRWRLKGNHPIETTRWVNAIQSAI----RFAKDKEILNKK 397 Query: 471 SGHP 482 P Sbjct: 398 KAVP 401
>Q9QY39:PDZD4_MOUSE PDZ domain-containing protein 4 - Mus musculus (Mouse)| Length = 772 Score = 37.7 bits (86), Expect = 0.056 Identities = 23/74 (31%), Positives = 32/74 (43%) Frame = -1 Query: 352 SPGVESSKANLRLSTSSAPLTVRQEATAMTPRGTDARVTVESLNQKSFPCLSTNHRRRHV 173 SPG S A R + + RQ R T VT+E + + P LS HR + + Sbjct: 525 SPG---SPAKFRSLSRDPEVGRRQHTEERVRRSTKTSVTLERVGPEGSPYLSRRHRGQEI 581 Query: 172 LMYSPCLSSHPPRS 131 Y C+ PPR+ Sbjct: 582 EQYHSCVQLAPPRT 595
>O74653:POB1_SCHPO Protein pob1 - Schizosaccharomyces pombe (Fission yeast)| Length = 871 Score = 37.4 bits (85), Expect = 0.073 Identities = 23/112 (20%), Positives = 47/112 (41%), Gaps = 11/112 (9%) Frame = +3 Query: 141 GWLDKQGEYIKTWRRRWFVLKQGKLFWFK-----------DSTVTRASVPRGVIAVASCL 287 GW+ K+ + W+ R+FVLK +L ++ D T R + ++ Sbjct: 703 GWMRKRSDRYGVWKSRYFVLKGTRLSYYHSLNDASEKGLIDMTSHRVTKTDDIVLSGGKT 762 Query: 288 TVKGAEDVLNRKFAFELSTPGETMYFVADSDKEKEDWINSIGRSIVQHSRSM 443 +K A + TP + YF ++++E W ++ ++ V+ S+ Sbjct: 763 AIKLIPPAPGAAKAAVMFTPPKVHYFTCENNEELHRWSSAFLKATVERDMSV 814
>Q13972:GNRP_HUMAN Guanine nucleotide-releasing protein - Homo sapiens (Human)| Length = 1275 Score = 37.0 bits (84), Expect = 0.096 Identities = 23/110 (20%), Positives = 51/110 (46%), Gaps = 11/110 (10%) Frame = +3 Query: 123 REPERGGWLDKQGEYIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVK-- 296 ++ R G+L K+ W+ +WF L Q LF+F+ + +R P G+ + C+ + Sbjct: 21 KDGTRKGYLSKRSSDNTKWQTKWFALLQNLLFYFESDSSSR---PSGLYLLEGCVCDRAP 77 Query: 297 ------GAEDVLNRKFAFELSTPGE---TMYFVADSDKEKEDWINSIGRS 419 A++ L ++ F ++ E + + K+ ++W+ +I + Sbjct: 78 SPKPALSAKEPLEKQHYFTVNFSHENQKALELRTEDAKDCDEWVAAIAHA 127
>Q9WU68:PKHB1_RAT Pleckstrin homology domain-containing family B member 1 - Rattus| norvegicus (Rat) Length = 223 Score = 36.6 bits (83), Expect = 0.12 Identities = 15/35 (42%), Positives = 21/35 (60%), Gaps = 1/35 (2%) Frame = +3 Query: 135 RGGWLDKQGEYIKTWRRRWFVL-KQGKLFWFKDST 236 RGGWL +Q ++ W+R WF L G L ++ D T Sbjct: 5 RGGWLWRQSSILRRWKRNWFALWLDGTLGYYHDET 39
>Q9QYE9:PKHB1_MOUSE Pleckstrin homology domain-containing family B member 1 - Mus| musculus (Mouse) Length = 243 Score = 36.6 bits (83), Expect = 0.12 Identities = 15/35 (42%), Positives = 21/35 (60%), Gaps = 1/35 (2%) Frame = +3 Query: 135 RGGWLDKQGEYIKTWRRRWFVL-KQGKLFWFKDST 236 RGGWL +Q ++ W+R WF L G L ++ D T Sbjct: 24 RGGWLWRQSSILRRWKRNWFALWLDGTLGYYHDET 58
>Q9UF11:PKHB1_HUMAN Pleckstrin homology domain-containing family B member 1 - Homo| sapiens (Human) Length = 243 Score = 36.6 bits (83), Expect = 0.12 Identities = 15/35 (42%), Positives = 21/35 (60%), Gaps = 1/35 (2%) Frame = +3 Query: 135 RGGWLDKQGEYIKTWRRRWFVL-KQGKLFWFKDST 236 RGGWL +Q ++ W+R WF L G L ++ D T Sbjct: 24 RGGWLWRQSSILRRWKRNWFALWLDGTLGYYHDET 58
>Q9BXB5:OSB10_HUMAN Oxysterol-binding protein-related protein 10 - Homo sapiens (Human)| Length = 764 Score = 36.6 bits (83), Expect = 0.12 Identities = 30/111 (27%), Positives = 54/111 (48%), Gaps = 2/111 (1%) Frame = +3 Query: 84 SASADATDGIEFWREPERGGWLDKQGEYIKTWRRRWFVL--KQGKLFWFKDSTVTRASVP 257 S +A + G REP G L K ++ W+ R+FVL + G L +F + ++ P Sbjct: 60 SVAASPSGGGGRRREPALEGVLSKYTNLLQGWQNRYFVLDFEAGILQYFVNEQ-SKHQKP 118 Query: 258 RGVIAVASCLTVKGAEDVLNRKFAFELSTPGETMYFVADSDKEKEDWINSI 410 RGV++++ + V +++ + + S GE A KEK+ W+ + Sbjct: 119 RGVLSLSGAI-VSLSDEAPHMLVVY--SANGEMFKLRAADAKEKQFWVTQL 166
>Q1RMU7:F109B_BOVIN Protein FAM109B - Bos taurus (Bovine)| Length = 259 Score = 36.6 bits (83), Expect = 0.12 Identities = 26/89 (29%), Positives = 43/89 (48%), Gaps = 3/89 (3%) Frame = +3 Query: 180 RRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFEL--STPGE 353 R+ WFVLK LF F+ P ++ + C TV+ AE + +FAF + PG Sbjct: 41 RKCWFVLKGNLLFSFES---REGRAPLSLVVLEGC-TVELAEAPVPEEFAFAIRFDAPGV 96 Query: 354 TMYFV-ADSDKEKEDWINSIGRSIVQHSR 437 + + AD +E W+ ++ R+ + R Sbjct: 97 RPHLLAADGPAAQEAWVKALSRASFGYMR 125
>Q9XTG7:AKT2_CAEEL Serine/threonine-protein kinase akt-2 - Caenorhabditis elegans| Length = 528 Score = 36.6 bits (83), Expect = 0.12 Identities = 29/105 (27%), Positives = 50/105 (47%), Gaps = 7/105 (6%) Frame = +3 Query: 144 WLDKQGEYIKTWRRRWFVL-KQGKLFWFKDSTVTRASVPRGV------IAVASCLTVKGA 302 WL K+GE+I+ WR R+F+L + G L F+ +P + A CL Sbjct: 18 WLHKKGEHIRNWRPRYFILFRDGTLLGFRSKPKEDQPLPEPLNNFMIRDAATVCLDKPRP 77 Query: 303 EDVLNRKFAFELSTPGETMYFVADSDKEKEDWINSIGRSIVQHSR 437 + R + +T E ++ ADS ++ WI +I +++ H+R Sbjct: 78 NMFIVR--CLQWTTVIERTFY-ADSADFRQMWIEAI-QAVSSHNR 118
>Q14644:RASA3_HUMAN Ras GTPase-activating protein 3 - Homo sapiens (Human)| Length = 834 Score = 36.2 bits (82), Expect = 0.16 Identities = 26/105 (24%), Positives = 49/105 (46%), Gaps = 1/105 (0%) Frame = +3 Query: 168 IKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTV-KGAEDVLNRKFAFELST 344 +K +++RWF L + + K ++ P I + + L V K E+ K F++ Sbjct: 595 MKNFKKRWFRLTNHEFTYHK----SKGDQPLYSIPIENILAVEKLEEESFKMKNMFQVIQ 650 Query: 345 PGETMYFVADSDKEKEDWINSIGRSIVQHSRSMTDDEIVDYDSGH 479 P +Y A++ E +DWI+ + + + + +T Y SGH Sbjct: 651 PERALYIQANNCVEAKDWIDILTKVSQCNQKRLTVYHPSAYLSGH 695
>Q9QZC7:PKHB2_MOUSE Pleckstrin homology domain-containing family B member 2 - Mus| musculus (Mouse) Length = 221 Score = 36.2 bits (82), Expect = 0.16 Identities = 17/55 (30%), Positives = 28/55 (50%), Gaps = 1/55 (1%) Frame = +3 Query: 135 RGGWLDKQGEYIKTWRRRWFVL-KQGKLFWFKDSTVTRASVPRGVIAVASCLTVK 296 + GWL +Q +K W++ WF L G L ++ D TR S+ V C+ ++ Sbjct: 5 KSGWLLRQSTILKRWKKNWFDLWSDGHLIYYDDQ--TRQSIEDKVHMPVDCINIR 57
>Q63312:PHLB1_RAT Pleckstrin homology-like domain family B member 1 - Rattus norvegicus| (Rat) Length = 831 Score = 36.2 bits (82), Expect = 0.16 Identities = 29/97 (29%), Positives = 44/97 (45%), Gaps = 7/97 (7%) Frame = +3 Query: 141 GWLDKQGEYIKTWRRRWFVLKQGK--LFWFKDSTVTRASVPRGVIAVASCLTV-----KG 299 G+L K G IK+W++RWFV + K L ++ D T+ +GVI + V + Sbjct: 726 GYLIKMGGKIKSWKKRWFVFDRLKRTLSYYVDKHETKL---KGVIYFQAIEEVYYDHLRS 782 Query: 300 AEDVLNRKFAFELSTPGETMYFVADSDKEKEDWINSI 410 A N F + T Y VA S + W++ I Sbjct: 783 AAKSPNPALTFCVKTHDRLYYMVAPSAEAMRIWMDVI 819
>Q6PDH0:PHLB1_MOUSE Pleckstrin homology-like domain family B member 1 - Mus musculus| (Mouse) Length = 1371 Score = 36.2 bits (82), Expect = 0.16 Identities = 29/97 (29%), Positives = 44/97 (45%), Gaps = 7/97 (7%) Frame = +3 Query: 141 GWLDKQGEYIKTWRRRWFVLKQGK--LFWFKDSTVTRASVPRGVIAVASCLTV-----KG 299 G+L K G IK+W++RWFV + K L ++ D T+ +GVI + V + Sbjct: 1266 GYLIKMGGKIKSWKKRWFVFDRLKRTLSYYVDKHETKL---KGVIYFQAIEEVYYDHLRS 1322 Query: 300 AEDVLNRKFAFELSTPGETMYFVADSDKEKEDWINSI 410 A N F + T Y VA S + W++ I Sbjct: 1323 AAKSPNPALTFCVKTHDRLYYMVAPSAEAMRIWMDVI 1359
>Q6ICB4:F109B_HUMAN Protein FAM109B - Homo sapiens (Human)| Length = 259 Score = 36.2 bits (82), Expect = 0.16 Identities = 27/91 (29%), Positives = 43/91 (47%), Gaps = 3/91 (3%) Frame = +3 Query: 174 TWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFEL--STP 347 T RR WFVLK LF F+ P ++ + C TV+ AE + +FAF + P Sbjct: 39 TGRRCWFVLKGNLLFSFES---REGRAPLSLVVLEGC-TVELAEAPVPEEFAFAICFDAP 94 Query: 348 GETMYFV-ADSDKEKEDWINSIGRSIVQHSR 437 G + + A+ +E W+ + R+ + R Sbjct: 95 GVRPHLLAAEGPAAQEAWVKVLSRASFGYMR 125
>Q5U464:DDFL1_MOUSE Development and differentiation-enhancing factor-like 1 - Mus| musculus (Mouse) Length = 904 Score = 36.2 bits (82), Expect = 0.16 Identities = 37/135 (27%), Positives = 65/135 (48%), Gaps = 1/135 (0%) Frame = +3 Query: 132 ERGGWLDKQGEYIK-TWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAED 308 E+ G+L K+ + I+ W++R +K G L S + R V + + +C E+ Sbjct: 304 EKVGFLYKKSDGIRRVWQKRKCGVKYGCLT-ISHSMINRPPVK---LPLLTCQVRPNPEE 359 Query: 309 VLNRKFAFELSTPGETMYFVADSDKEKEDWINSIGRSIVQHSRSMTDDEIVDYDSGHPAT 488 K F+L T T +F A+ ++E E W+ S++Q+S+ D+ + + G P+ Sbjct: 360 ----KRCFDLVTHNRTYHFHAEDEQECEAWV-----SVLQNSK---DEALSNAFHGEPSG 407 Query: 489 GRKS*VRRLIGEQKD 533 G+ S RL E D Sbjct: 408 GQWSWGTRLDTEPHD 422
>Q10165:YAUA_SCHPO Uncharacterized protein C26A3.10 - Schizosaccharomyces pombe| (Fission yeast) Length = 923 Score = 35.8 bits (81), Expect = 0.21 Identities = 24/81 (29%), Positives = 38/81 (46%), Gaps = 3/81 (3%) Frame = +3 Query: 177 WRRRWFVLKQGKLFWF---KDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTP 347 W + W V++ G L+ + KDS + S A A + +G R+F FE+ TP Sbjct: 553 WHKHWIVVENGSLWEYANWKDSVKSNVSSISLKHASADKVRKQG------RRFCFEVVTP 606 Query: 348 GETMYFVADSDKEKEDWINSI 410 + A S +E + WI +I Sbjct: 607 KLKRLYQATSAEEMDSWIEAI 627
>P10686:PLCG1_RAT 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 -| Rattus norvegicus (Rat) Length = 1290 Score = 35.8 bits (81), Expect = 0.21 Identities = 21/60 (35%), Positives = 29/60 (48%), Gaps = 3/60 (5%) Frame = +3 Query: 258 RGVIAVASCLTVKGAEDVLNRKFAFELSTPGETMY---FVADSDKEKEDWINSIGRSIVQ 428 RGV+ V +C E NR F F +S P + ADS +E +DW+ I R + Q Sbjct: 873 RGVLDVPACQIAIRPEGKNNRLFVFSISMPSVAQWSLDVAADSQEELQDWVKKI-REVAQ 931
>Q62077:PLCG1_MOUSE 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 -| Mus musculus (Mouse) Length = 1302 Score = 35.8 bits (81), Expect = 0.21 Identities = 21/60 (35%), Positives = 29/60 (48%), Gaps = 3/60 (5%) Frame = +3 Query: 258 RGVIAVASCLTVKGAEDVLNRKFAFELSTPGETMY---FVADSDKEKEDWINSIGRSIVQ 428 RGV+ V +C E NR F F +S P + ADS +E +DW+ I R + Q Sbjct: 873 RGVLDVPACQIAIRPEGKNNRLFVFSISMPSVAQWSLDVAADSQEELQDWVKKI-REVAQ 931
>Q5R4K6:PKHB2_PONPY Pleckstrin homology domain-containing family B member 2 - Pongo| pygmaeus (Orangutan) Length = 222 Score = 35.8 bits (81), Expect = 0.21 Identities = 16/59 (27%), Positives = 30/59 (50%), Gaps = 1/59 (1%) Frame = +3 Query: 135 RGGWLDKQGEYIKTWRRRWFVL-KQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAED 308 + GWL +Q +K W++ WF L G L ++ D TR ++ V C+ ++ ++ Sbjct: 5 KSGWLLRQSTILKRWKKNWFDLWSDGHLIYYDDQ--TRQNIEDKVHMPVDCINIRTGQE 61
>Q8TDY4:DDFL1_HUMAN Development and differentiation-enhancing factor-like 1 - Homo| sapiens (Human) Length = 903 Score = 35.8 bits (81), Expect = 0.21 Identities = 33/121 (27%), Positives = 58/121 (47%), Gaps = 1/121 (0%) Frame = +3 Query: 132 ERGGWLDKQGEYIK-TWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAED 308 E+ G+L K+ + I+ W++R +K G L ST+ R V + + +C E+ Sbjct: 304 EKVGFLYKKSDGIRRVWQKRKCGVKYGCLT-ISHSTINRPPVK---LTLLTCQVRPNPEE 359 Query: 309 VLNRKFAFELSTPGETMYFVADSDKEKEDWINSIGRSIVQHSRSMTDDEIVDYDSGHPAT 488 K F+L T T +F A+ + E E W+ S++Q+S+ D+ + G P+ Sbjct: 360 ----KKCFDLVTHNRTYHFQAEDEHECEAWV-----SVLQNSK---DEALSSAFLGEPSA 407 Query: 489 G 491 G Sbjct: 408 G 408
>Q6C8M8:ATG26_YARLI Sterol 3-beta-glucosyltransferase - Yarrowia lipolytica (Candida| lipolytica) Length = 1424 Score = 35.8 bits (81), Expect = 0.21 Identities = 21/82 (25%), Positives = 38/82 (46%), Gaps = 2/82 (2%) Frame = +3 Query: 183 RRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDV--LNRKFAFELSTPGET 356 R W VLK ++ DST P G I ++ L + +D + +F + P ++ Sbjct: 239 RYWCVLKNDSFSYYPDST--DVYFPAGTIDLSEALAAELCDDEGDVTEPESFRIVMPKKS 296 Query: 357 MYFVADSDKEKEDWINSIGRSI 422 + F ADS +W+ ++ + I Sbjct: 297 VLFKADSHSAAHEWVKALQKEI 318
>Q6PG29:SKAP2_DANRE Src kinase-associated phosphoprotein 2 - Danio rerio (Zebrafish)| (Brachydanio rerio) Length = 341 Score = 35.4 bits (80), Expect = 0.28 Identities = 26/117 (22%), Positives = 52/117 (44%), Gaps = 5/117 (4%) Frame = +3 Query: 135 RGGWLDKQGE----YIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGA 302 + G+L+K+ + + W++RW L +++ + ++ + Sbjct: 108 KSGYLEKRRKDHSFFGNEWQKRWCALNNSIFYYYGSEKDKQQKGEFNIVGYTVKMNNTLR 167 Query: 303 EDVLNRKFAFELSTPGETMY-FVADSDKEKEDWINSIGRSIVQHSRSMTDDEIVDYD 470 +D R FE+S P + +Y F A S+KE ++W+ I I + +DE +YD Sbjct: 168 KDA-KRDCCFEVSAPDKRVYQFCAASEKEAKEWVEHIDFLIKDLGGIIPEDE-EEYD 222
>Q86WV1:SKAP1_HUMAN Src kinase-associated phosphoprotein 1 - Homo sapiens (Human)| Length = 359 Score = 35.4 bits (80), Expect = 0.28 Identities = 23/98 (23%), Positives = 49/98 (50%), Gaps = 8/98 (8%) Frame = +3 Query: 141 GWLDKQGE----YIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAED 308 G+L+K+ + + W++RW V+ +G +++ + ++ P+G + +V+ A Sbjct: 112 GYLEKKSKDHSFFGSEWQKRWCVVSRGLFYYYANE---KSKQPKGTFLIKG-YSVRMAPH 167 Query: 309 V---LNRKFAFELSTPGETMY-FVADSDKEKEDWINSI 410 + ++ FEL++ Y F A S E DW++ I Sbjct: 168 LRRDSKKESCFELTSQDRRSYEFTATSPAEARDWVDQI 205
>Q96CS7:PKHB2_HUMAN Pleckstrin homology domain-containing family B member 2 - Homo| sapiens (Human) Length = 222 Score = 35.4 bits (80), Expect = 0.28 Identities = 16/59 (27%), Positives = 30/59 (50%), Gaps = 1/59 (1%) Frame = +3 Query: 135 RGGWLDKQGEYIKTWRRRWFVL-KQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAED 308 + GWL +Q +K W++ WF L G L ++ D TR ++ V C+ ++ ++ Sbjct: 5 KSGWLLRQSTILKRWKKNWFDLWSDGHLIYYDDQ--TRQNIEDKVHMPMDCINIRTGQE 61
>Q9H4L5:OSBL3_HUMAN Oxysterol-binding protein-related protein 3 - Homo sapiens (Human)| Length = 887 Score = 35.4 bits (80), Expect = 0.28 Identities = 35/145 (24%), Positives = 64/145 (44%), Gaps = 5/145 (3%) Frame = +3 Query: 111 IEFWREP--ERGGWLDKQGEYIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVA-S 281 + + +EP ++G L K+ +K W +R+F L +G L + K T G I V S Sbjct: 45 MNYTQEPPVQKGFLLKKRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLS 104 Query: 282 CLTVKGAEDVLNRKFAFELSTPGETMYFVADSDKEKEDWINSI--GRSIVQHSRSMTDDE 455 ++VK + + +L T + S++ ++W++ + R Q+ +M E Sbjct: 105 VMSVKKSSKCI------DLDTEEHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAMFPHE 158 Query: 456 IVDYDSGHPATGRKS*VRRLIGEQK 530 + + SG T S V I +K Sbjct: 159 VNHFFSGSTITDSSSGVFDSISSRK 183
>Q5KK25:ATG26_CRYNE Sterol 3-beta-glucosyltransferase - Cryptococcus neoformans| (Filobasidiella neoformans) Length = 1585 Score = 35.4 bits (80), Expect = 0.28 Identities = 24/95 (25%), Positives = 43/95 (45%), Gaps = 3/95 (3%) Frame = +3 Query: 135 RGGWLDKQGEYIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVA---SCLTVKGAE 305 + G L K+ K + W VLK L W++ + + P+G I++ SC V G Sbjct: 441 KSGPLHKKASRSKLNTKFWVVLKNDVLSWYE--STSDPYFPKGNISLQYCHSCDAVSGTR 498 Query: 306 DVLNRKFAFELSTPGETMYFVADSDKEKEDWINSI 410 F++ T F AD++ +++W+ +I Sbjct: 499 --------FKVRTSERNYTFTADTESSRDEWVKAI 525
>Q6NTN5:MTMRD_XENLA Myotubularin-related protein 13 - Xenopus laevis (African clawed| frog) Length = 1873 Score = 35.0 bits (79), Expect = 0.36 Identities = 29/102 (28%), Positives = 44/102 (43%), Gaps = 8/102 (7%) Frame = +3 Query: 141 GWLDKQGEYIKTWRRRWFVL--KQGKLFWFKDSTVTRASVPRGVIAVASCLTVK------ 296 G L K+G +K W+ RWFVL + +L ++ T +G I +A TV Sbjct: 1772 GILYKRGALLKGWKPRWFVLDITKHQLRYYDSGEDTSC---KGYIDLADVETVVPAAPTI 1828 Query: 297 GAEDVLNRKFAFELSTPGETMYFVADSDKEKEDWINSIGRSI 422 GA N K F++ T F A + + W++ I I Sbjct: 1829 GAPKHANEKAFFDVKTSKRVYNFCAQDAQSAQLWMDKIQNCI 1870
>Q17941:AKT1_CAEEL Serine/threonine-protein kinase akt-1 - Caenorhabditis elegans| Length = 541 Score = 35.0 bits (79), Expect = 0.36 Identities = 28/103 (27%), Positives = 44/103 (42%), Gaps = 13/103 (12%) Frame = +3 Query: 141 GWLDKQGEYIKTWRRRWF-VLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLN 317 GWL K+GE+I+ WR R+F + G L F+ P + + +K A +L Sbjct: 20 GWLHKKGEHIRNWRPRYFMIFNDGALLGFRAKPKEGQPFPEPL----NDFMIKDAATML- 74 Query: 318 RKFAFELSTPGETMY------------FVADSDKEKEDWINSI 410 FE P M F A+S + ++ WI++I Sbjct: 75 ----FEKPRPNMFMVRCLQWTTVIERTFYAESAEVRQRWIHAI 113
>Q9P7Y8:MID2_SCHPO Septin ring organizing protein mid2 - Schizosaccharomyces pombe| (Fission yeast) Length = 704 Score = 34.3 bits (77), Expect = 0.62 Identities = 29/104 (27%), Positives = 50/104 (48%), Gaps = 6/104 (5%) Frame = +3 Query: 141 GWLDKQGEYIKTWRRRWFVLKQGKLFWFKD-STVTRASVPRGVIAVASCLTVKGAEDVLN 317 G+L +QG WRRR+F L KL F+ S V RA++ E+ L Sbjct: 586 GYLCQQGGDCPYWRRRYFQLIGSKLVAFQQFSKVRRATIDLSEATHIVDDNHYSDEEELE 645 Query: 318 RKFAFE-----LSTPGETMYFVADSDKEKEDWINSIGRSIVQHS 434 FE + + G+ + F A++ EK++W++++ + + Q S Sbjct: 646 GYLYFESGFRIIFSNGDYIDFYAETVGEKDEWMSTLRQHLGQCS 689
>Q9Y4H2:IRS2_HUMAN Insulin receptor substrate 2 - Homo sapiens (Human)| Length = 1338 Score = 34.3 bits (77), Expect = 0.62 Identities = 19/71 (26%), Positives = 34/71 (47%) Frame = +3 Query: 240 TRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPGETMYFVADSDKEKEDWINSIGRS 419 ++A P+ VIA+ CL + D K+ L T E A++++E+E W ++ Sbjct: 84 SKAGAPKRVIALDCCLNINKRADA-KHKYLIALYTKDEYFAVAAENEQEQEGWYRAL-TD 141 Query: 420 IVQHSRSMTDD 452 +V R+ D Sbjct: 142 LVSEGRAAAGD 152
>Q1AAU6:DDEF1_RAT 130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1| GTPase-activating protein - Rattus norvegicus (Rat) Length = 1144 Score = 34.3 bits (77), Expect = 0.62 Identities = 28/99 (28%), Positives = 50/99 (50%), Gaps = 3/99 (3%) Frame = +3 Query: 132 ERGGWLDKQGEYI-KTWRRRWFVLKQGKLFWFKDSTVTRASVPR--GVIAVASCLTVKGA 302 E+ G+L K+ + I K W+RR +K G L T++ A+ R + + +C A Sbjct: 338 EKKGFLLKKSDGIRKVWQRRKCAVKNGIL------TISHATSNRQPAKLNLLTCQVKPNA 391 Query: 303 EDVLNRKFAFELSTPGETMYFVADSDKEKEDWINSIGRS 419 ED K +F+L + T +F A+ +++ WI+ + S Sbjct: 392 ED----KKSFDLISHNRTYHFQAEDEQDYVAWISVLTNS 426
>P38041:BOB1_YEAST Protein BOB1 - Saccharomyces cerevisiae (Baker's yeast)| Length = 980 Score = 34.3 bits (77), Expect = 0.62 Identities = 29/124 (23%), Positives = 56/124 (45%), Gaps = 23/124 (18%) Frame = +3 Query: 141 GWLDKQGE-YIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAED--- 308 GW+ K+G + TW++R+F L +L +F T T RG+I + + + ++D Sbjct: 781 GWMSKKGTGAMGTWKQRFFTLHGTRLSYF---TNTNDEKERGLIDITAHRVLPASDDDRL 837 Query: 309 -------VLNRKFAFELSTP------GETM------YFVADSDKEKEDWINSIGRSIVQH 431 + K+ F+L P G T YF ++ E + W+++I ++ + Sbjct: 838 ISLYAASLGKGKYCFKLVPPQPGSKKGLTFTEPRVHYFAVENKSEMKAWLSAIIKATIDI 897 Query: 432 SRSM 443 S+ Sbjct: 898 DTSV 901
>P08640:MUC1_YEAST Mucin-like protein 1 precursor - Saccharomyces cerevisiae (Baker's| yeast) Length = 1367 Score = 34.3 bits (77), Expect = 0.62 Identities = 36/144 (25%), Positives = 61/144 (42%), Gaps = 5/144 (3%) Frame = -1 Query: 475 PLS*STISSSVMDRECWTMERPMELIQSSFSLSESATKYMVSPGVESSKANLRLSTSSAP 296 P S +T SSS T + S S +ES++ + S ESS A + ST+ + Sbjct: 332 PSSSTTESSSAPVTSSTTESSSAPVPTPSSSTTESSSAPVTSSTTESSSAPVTSSTTESS 391 Query: 295 LTVRQEATAMTPRGTDARVTVESLNQKSFPCLS--TNHRRRHVLMYSPCLSSHPPRSGSR 122 ++ T + A VT + S P S T V + SS P S + Sbjct: 392 SAPVPTPSSSTTESSSAPVTSSTTESSSAPVTSSTTESSSAPVTSSTTESSSAPVTSSTT 451 Query: 121 QNS---MPSVASADADGAPVPITA 59 ++S +P+ +S+ + + P+T+ Sbjct: 452 ESSSAPVPTPSSSTTESSSAPVTS 475 Score = 33.5 bits (75), Expect = 1.1 Identities = 43/161 (26%), Positives = 64/161 (39%), Gaps = 9/161 (5%) Frame = -1 Query: 523 SPINRRTYDLRPVAGWPLS*STISSSVMDRECWTMERPMELIQSSFSLSESATKYMVSPG 344 +P + T A P S +T SSS T + S S +ES++ + S Sbjct: 514 TPSSSTTESSSAPAPTPSSSTTESSSAPVTSSTTESSSAPVPTPSSSTTESSSTPVTSST 573 Query: 343 VESSKA------NLRLSTSSAPLTVRQEAT---AMTPRGTDARVTVESLNQKSFPCLSTN 191 ESS A + +SSAP+ +T + P T + T ES S P S+ Sbjct: 574 TESSSAPVPTPSSSTTESSSAPVPTPSSSTTESSSAPAPTPSSSTTES---SSAPVTSST 630 Query: 190 HRRRHVLMYSPCLSSHPPRSGSRQNSMPSVASADADGAPVP 68 + +P SS S S PS ++ ++ APVP Sbjct: 631 TESSSAPVPTP--SSSTTESSSAPVPTPSSSTTESSSAPVP 669
>O14340:YB35_SCHPO Oxysterol-binding protein homolog C2F12.05c - Schizosaccharomyces| pombe (Fission yeast) Length = 1310 Score = 33.9 bits (76), Expect = 0.81 Identities = 36/128 (28%), Positives = 54/128 (42%), Gaps = 1/128 (0%) Frame = +3 Query: 42 MASLWRAVMGTGAPSASADATDGIEFWREPERGGWLDKQGEYIKTWRRRWFVLKQGKLFW 221 M SL R+ G S+SA A G+L K Y ++ RWF L G L + Sbjct: 234 MRSLLRSYSGN-RDSSSAPAVP-------QHMSGYLKKWTNYKSGYKLRWFTLNNGVLSY 285 Query: 222 FKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPGETMYFV-ADSDKEKEDW 398 +K+ +S RG I + V + + F++ G Y V A+S E + W Sbjct: 286 YKNQD-DASSACRGSINLKLARLVHDPK----QPTVFQVIGKGSVRYSVKANSPVEAKKW 340 Query: 399 INSIGRSI 422 I +I +I Sbjct: 341 IAAISSAI 348
>Q3UUV5:SKAP1_MOUSE Src kinase-associated phosphoprotein 1 - Mus musculus (Mouse)| Length = 355 Score = 33.9 bits (76), Expect = 0.81 Identities = 23/98 (23%), Positives = 47/98 (47%), Gaps = 8/98 (8%) Frame = +3 Query: 141 GWLDKQGE----YIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAED 308 G+L+K+ + + W++RW V+ +G ++ + ++ P+G + +V+ A Sbjct: 112 GYLEKKSKDHSFFGSEWQKRWCVISRGLFLYYANE---KSKQPKGTFLIKG-YSVRMAPH 167 Query: 309 V---LNRKFAFELSTPGETMY-FVADSDKEKEDWINSI 410 + ++ FEL + Y F A S E DW++ I Sbjct: 168 LRKDSKKESCFELISQDRRSYEFTASSPAEARDWVDQI 205
>Q03428:NRKB_TRYBB Putative serine/threonine-protein kinase B - Trypanosoma brucei| brucei Length = 431 Score = 33.9 bits (76), Expect = 0.81 Identities = 28/89 (31%), Positives = 45/89 (50%), Gaps = 5/89 (5%) Frame = +3 Query: 171 KTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDV----LNRKFAFEL 338 K+W+ R+ + +G+L D + P+G+ + V+GA V R F F L Sbjct: 347 KSWKPRFLQIVRGQLILTDDE---EGNNPKGL----NLEQVQGACPVPYSTAKRDFVFAL 399 Query: 339 STPG-ETMYFVADSDKEKEDWINSIGRSI 422 +T G E M+F A S + E W+++I R I Sbjct: 400 NTVGGEGMWFQAVSHGDMEMWVHAIQRGI 428
>P81122:IRS2_MOUSE Insulin receptor substrate 2 - Mus musculus (Mouse)| Length = 1321 Score = 33.9 bits (76), Expect = 0.81 Identities = 19/67 (28%), Positives = 33/67 (49%) Frame = +3 Query: 240 TRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPGETMYFVADSDKEKEDWINSIGRS 419 ++A P+ VIA+ CL + D K+ L T E A++++E+E W ++ Sbjct: 84 SKAGAPKRVIALDCCLNINKRADA-KHKYLIALYTKDEYFAVAAENEQEQEGWYRAL-TD 141 Query: 420 IVQHSRS 440 +V RS Sbjct: 142 LVSEGRS 148
>P27671:GNRP_MOUSE Guanine nucleotide-releasing protein - Mus musculus (Mouse)| Length = 1262 Score = 33.9 bits (76), Expect = 0.81 Identities = 25/118 (21%), Positives = 50/118 (42%), Gaps = 12/118 (10%) Frame = +3 Query: 102 TDGIEFWREPERGGWLDKQGEYIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVAS 281 T G+ ++ R G+L K+ W+ +WF L Q LF+F+ + R P G+ + Sbjct: 14 TLGLLAQKDGTRKGYLSKRSADNPKWQTKWFALLQNLLFYFESDSSPR---PSGLYLLEG 70 Query: 282 CL-----------TVKGAEDVLNRKFAFELSTPGE-TMYFVADSDKEKEDWINSIGRS 419 + + K + + F S + T+ + K+ ++W+ +I R+ Sbjct: 71 SICKRAPSPKRGTSSKESGEKQQHYFTVNFSNDSQKTLELRTEDAKDCDEWVAAIARA 128
>Q9QWY8:DDEF1_MOUSE 130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1| GTPase-activating protein - Mus musculus (Mouse) Length = 1147 Score = 33.9 bits (76), Expect = 0.81 Identities = 28/99 (28%), Positives = 50/99 (50%), Gaps = 3/99 (3%) Frame = +3 Query: 132 ERGGWLDKQGEYI-KTWRRRWFVLKQGKLFWFKDSTVTRASVPR--GVIAVASCLTVKGA 302 E+ G+L K+ + I K W+RR +K G L T++ A+ R + + +C A Sbjct: 341 EKKGFLLKKSDGIRKVWQRRKCAVKNGIL------TISHATSNRQPAKLNLLTCQVKPNA 394 Query: 303 EDVLNRKFAFELSTPGETMYFVADSDKEKEDWINSIGRS 419 ED K +F+L + T +F A+ +++ WI+ + S Sbjct: 395 ED----KKSFDLISHNRTYHFQAEDEQDYIAWISVLTNS 429
>Q9ULH1:DDEF1_HUMAN 130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1| GTPase-activating protein - Homo sapiens (Human) Length = 1129 Score = 33.9 bits (76), Expect = 0.81 Identities = 28/99 (28%), Positives = 50/99 (50%), Gaps = 3/99 (3%) Frame = +3 Query: 132 ERGGWLDKQGEYI-KTWRRRWFVLKQGKLFWFKDSTVTRASVPR--GVIAVASCLTVKGA 302 E+ G+L K+ + I K W+RR +K G L T++ A+ R + + +C A Sbjct: 326 EKKGYLLKKSDGIRKVWQRRKCSVKNGIL------TISHATSNRQPAKLNLLTCQVKPNA 379 Query: 303 EDVLNRKFAFELSTPGETMYFVADSDKEKEDWINSIGRS 419 ED K +F+L + T +F A+ +++ WI+ + S Sbjct: 380 ED----KKSFDLISHNRTYHFQAEDEQDYVAWISVLTNS 414
>O97902:DDEF1_BOVIN 130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1| GTPase-activating protein - Bos taurus (Bovine) Length = 1129 Score = 33.9 bits (76), Expect = 0.81 Identities = 28/99 (28%), Positives = 50/99 (50%), Gaps = 3/99 (3%) Frame = +3 Query: 132 ERGGWLDKQGEYI-KTWRRRWFVLKQGKLFWFKDSTVTRASVPR--GVIAVASCLTVKGA 302 E+ G+L K+ + I K W+RR +K G L T++ A+ R + + +C A Sbjct: 329 EKKGYLLKKSDGIRKVWQRRKCSVKNGIL------TISHATSNRQPAKLNLLTCQVKPNA 382 Query: 303 EDVLNRKFAFELSTPGETMYFVADSDKEKEDWINSIGRS 419 ED K +F+L + T +F A+ +++ WI+ + S Sbjct: 383 ED----KKSFDLISHNRTYHFQAEDEQDYVAWISVLTNS 417
>Q4V7G1:SKAP1_RAT Src kinase-associated phosphoprotein 1 - Rattus norvegicus (Rat)| Length = 354 Score = 33.5 bits (75), Expect = 1.1 Identities = 30/140 (21%), Positives = 60/140 (42%), Gaps = 26/140 (18%) Frame = +3 Query: 69 GTGAPSASADATDGIEFWREPE------------------RGGWLDKQGE----YIKTWR 182 GT P+ ++DA+ FW + + + G+L+K+ + + W+ Sbjct: 74 GTHGPALASDAS----FWSDYQEEGIDDIIRGAQELDNVIKQGYLEKKSKDHSFFGSEWQ 129 Query: 183 RRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDV---LNRKFAFELSTPGE 353 +RW V+ +G ++ + ++ P+G + V+ A + + FEL++ Sbjct: 130 KRWCVISRGLFLYYANE---KSKQPKGTFLIKG-YNVRMAPHLRKDSKKDSCFELTSQDR 185 Query: 354 TMY-FVADSDKEKEDWINSI 410 Y F A S E DW++ I Sbjct: 186 RSYEFTAFSPAEARDWVDQI 205
>Q9QYJ2:RASA3_RAT Ras GTPase-activating protein 3 - Rattus norvegicus (Rat)| Length = 834 Score = 33.5 bits (75), Expect = 1.1 Identities = 25/105 (23%), Positives = 50/105 (47%), Gaps = 1/105 (0%) Frame = +3 Query: 168 IKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNR-KFAFELST 344 +K +++RWF L + + K ++ P I + + L V+ E+ R K F++ Sbjct: 595 MKNFKKRWFRLTNHEFTYQK----SKGDQPLCNIPIENILAVERLEEESFRMKNMFQVIQ 650 Query: 345 PGETMYFVADSDKEKEDWINSIGRSIVQHSRSMTDDEIVDYDSGH 479 P +Y A++ E +DWI+ + + + + +T Y +GH Sbjct: 651 PERALYIQANNCVEAKDWIDILTKVSQCNQKRLTVFHPSAYLNGH 695
>Q60790:RASA3_MOUSE Ras GTPase-activating protein 3 - Mus musculus (Mouse)| Length = 834 Score = 33.5 bits (75), Expect = 1.1 Identities = 25/105 (23%), Positives = 50/105 (47%), Gaps = 1/105 (0%) Frame = +3 Query: 168 IKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNR-KFAFELST 344 +K +++RWF L + + K ++ P I + + L V+ E+ R K F++ Sbjct: 595 MKNFKKRWFRLTNHEFTYQK----SKGDQPLCNIPIENILAVERLEEESFRMKNMFQVIQ 650 Query: 345 PGETMYFVADSDKEKEDWINSIGRSIVQHSRSMTDDEIVDYDSGH 479 P +Y A++ E +DWI+ + + + + +T Y +GH Sbjct: 651 PERALYIQANNCVEAKDWIDILTKVSQCNQKRLTVFHPSAYLNGH 695
>P35570:IRS1_RAT Insulin receptor substrate 1 - Rattus norvegicus (Rat)| Length = 1235 Score = 33.5 bits (75), Expect = 1.1 Identities = 31/117 (26%), Positives = 52/117 (44%), Gaps = 9/117 (7%) Frame = +3 Query: 87 ASADATDGIEFWREPERGGWLDKQGEYIKTWRRRWFVLKQG-------KLFWFKDSTVTR 245 AS TDG + + G+L K K+ +R+FVL+ +L ++++ R Sbjct: 2 ASPPDTDGFS---DVRKVGYLRKP----KSMHKRFFVLRAASEAGGPARLEYYENEKKWR 54 Query: 246 --ASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPGETMYFVADSDKEKEDWINSI 410 +S P+ I + SC + D N K L T E ADS+ E++ W ++ Sbjct: 55 HKSSAPKRSIPLESCFNINKRADSKN-KHLVALYTRDEHFAIAADSEAEQDSWYQAL 110
>P35569:IRS1_MOUSE Insulin receptor substrate 1 - Mus musculus (Mouse)| Length = 1233 Score = 33.5 bits (75), Expect = 1.1 Identities = 31/117 (26%), Positives = 52/117 (44%), Gaps = 9/117 (7%) Frame = +3 Query: 87 ASADATDGIEFWREPERGGWLDKQGEYIKTWRRRWFVLKQG-------KLFWFKDSTVTR 245 AS TDG + + G+L K K+ +R+FVL+ +L ++++ R Sbjct: 2 ASPPDTDGFS---DVRKVGYLRKP----KSMHKRFFVLRAASEAGGPARLEYYENEKKWR 54 Query: 246 --ASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPGETMYFVADSDKEKEDWINSI 410 +S P+ I + SC + D N K L T E ADS+ E++ W ++ Sbjct: 55 HKSSAPKRSIPLESCFNINKRADSKN-KHLVALYTRDEHFAIAADSEAEQDSWYQAL 110
>Q8WXI7:MUC16_HUMAN Mucin-16 - Homo sapiens (Human)| Length = 22152 Score = 33.5 bits (75), Expect = 1.1 Identities = 30/128 (23%), Positives = 52/128 (40%) Frame = -1 Query: 385 SLSESATKYMVSPGVESSKANLRLSTSSAPLTVRQEATAMTPRGTDARVTVESLNQKSFP 206 S+ E A +PG +K R STS +++++TA+ T TV S Sbjct: 6048 SMMEDAIVSTSTPGSPETKNVDRDSTSPLTPELKEDSTALVMNSTTESNTVFSSVSLD-- 6105 Query: 205 CLSTNHRRRHVLMYSPCLSSHPPRSGSRQNSMPSVASADADGAPVPITARHKLAMRCGGI 26 +T R V Y P +S + P +S+ ++ P+ I+ +A + G Sbjct: 6106 -AATEVSRAEVTYYDPTFMPASAQSTKSPDISPEASSSHSNSPPLTISTHKTIATQTGPS 6164 Query: 25 WGSGRGEL 2 + G+L Sbjct: 6165 GVTSLGQL 6172
>P91620:SIF2_DROME Protein still life, isoforms C/SIF type 2 - Drosophila melanogaster| (Fruit fly) Length = 2061 Score = 33.1 bits (74), Expect = 1.4 Identities = 37/133 (27%), Positives = 62/133 (46%), Gaps = 9/133 (6%) Frame = +3 Query: 39 LMASLWRAVMGTGAPSASADATDGIEFWREPERGGWLDKQGEYIKTWRRR-----WFVLK 203 +MAS ++A TG ++S + T + WL ++ I+ R+R W LK Sbjct: 800 VMASPYKA-KATGTAASSFNCTGAVRKAGFLSVKKWLLRKKHQIELARKRGWKGYWVCLK 858 Query: 204 QGKLFWFK-DSTVTRA--SVPRGVIAVASCLTVKGAEDVLNRKFAFELSTP-GETMYFVA 371 L ++ DS R+ + P+ +I V + ++ + R + F LST G+ F A Sbjct: 859 GTTLLFYPCDSREGRSVEAAPKHLIIVDGAI-MQPIPEHPKRDYIFCLSTAFGDAYLFQA 917 Query: 372 DSDKEKEDWINSI 410 E E+W+NSI Sbjct: 918 PCQVELENWVNSI 930
>P91621:SIF1_DROME Protein still life, isoform SIF type 1 - Drosophila melanogaster| (Fruit fly) Length = 2072 Score = 33.1 bits (74), Expect = 1.4 Identities = 37/133 (27%), Positives = 62/133 (46%), Gaps = 9/133 (6%) Frame = +3 Query: 39 LMASLWRAVMGTGAPSASADATDGIEFWREPERGGWLDKQGEYIKTWRRR-----WFVLK 203 +MAS ++A TG ++S + T + WL ++ I+ R+R W LK Sbjct: 820 VMASPYKA-KATGTAASSFNCTGAVRKAGFLSVKKWLLRKKHQIELARKRGWKGYWVCLK 878 Query: 204 QGKLFWFK-DSTVTRA--SVPRGVIAVASCLTVKGAEDVLNRKFAFELSTP-GETMYFVA 371 L ++ DS R+ + P+ +I V + ++ + R + F LST G+ F A Sbjct: 879 GTTLLFYPCDSREGRSVEAAPKHLIIVDGAI-MQPIPEHPKRDYIFCLSTAFGDAYLFQA 937 Query: 372 DSDKEKEDWINSI 410 E E+W+NSI Sbjct: 938 PCQVELENWVNSI 950
>Q63713:RASA2_RAT Ras GTPase-activating protein 2 - Rattus norvegicus (Rat)| Length = 847 Score = 33.1 bits (74), Expect = 1.4 Identities = 25/91 (27%), Positives = 44/91 (48%), Gaps = 2/91 (2%) Frame = +3 Query: 171 KTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDV-LNRKFAFELSTP 347 K +++RWF L +L + K I V + L V+ E+ N+K F++ Sbjct: 623 KNFKKRWFCLTSKELTYHKQQGKDAIYT----IPVKNILAVEKLEESSFNKKNMFQVIHT 678 Query: 348 GETMYFVADSDKEKEDWINSIGR-SIVQHSR 437 +T+Y A++ E +WI+ + R S H+R Sbjct: 679 EKTLYIQANNCVEANEWIDMLCRVSRCNHNR 709
>P19174:PLCG1_HUMAN 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 -| Homo sapiens (Human) Length = 1290 Score = 33.1 bits (74), Expect = 1.4 Identities = 20/72 (27%), Positives = 33/72 (45%), Gaps = 3/72 (4%) Frame = +3 Query: 258 RGVIAVASCLTVKGAEDVLNRKFAFELSTPGETMYFV---ADSDKEKEDWINSIGRSIVQ 428 RGV+ V +C E NR F F +S + + ADS +E +DW+ I Sbjct: 873 RGVLDVPACQIAIRPEGKNNRLFVFSISMASVAHWSLDVAADSQEELQDWVKKIREVAQT 932 Query: 429 HSRSMTDDEIVD 464 +T+ +I++ Sbjct: 933 ADARLTEGKIME 944
>Q86WG5:MTMRD_HUMAN Myotubularin-related protein 13 - Homo sapiens (Human)| Length = 1849 Score = 33.1 bits (74), Expect = 1.4 Identities = 28/98 (28%), Positives = 41/98 (41%), Gaps = 8/98 (8%) Frame = +3 Query: 141 GWLDKQGEYIKTWRRRWFVLKQGK--LFWFKDSTVTRASVPRGVIAVASCLTV------K 296 G L K+G +K W+ RWFVL K L ++ T +G I +A V Sbjct: 1748 GTLYKRGALLKGWKPRWFVLDVTKHQLRYYDSGEDTSC---KGHIDLAEVEMVIPAGPSM 1804 Query: 297 GAEDVLNRKFAFELSTPGETMYFVADSDKEKEDWINSI 410 GA + K F+L T F A + + W++ I Sbjct: 1805 GAPKHTSDKAFFDLKTSKRVYNFCAQDGQSAQQWMDKI 1842
>Q9Y4F1:FARP1_HUMAN FERM, RhoGEF and pleckstrin domain-containing protein 1 - Homo| sapiens (Human) Length = 1045 Score = 33.1 bits (74), Expect = 1.4 Identities = 22/89 (24%), Positives = 38/89 (42%), Gaps = 2/89 (2%) Frame = +3 Query: 177 WRRRWFVLKQGKLFWFKDSTVTR--ASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPG 350 W++ W V LF++K AS+P + LT+ + + + + F+L Sbjct: 949 WQKLWVVFTNFCLFFYKSHQDNHPLASLP----LLGYSLTIPSESENIQKDYVFKLHFKS 1004 Query: 351 ETMYFVADSDKEKEDWINSIGRSIVQHSR 437 YF A+S+ E W+ I + SR Sbjct: 1005 HVYYFRAESEYTFERWMEVIRSATSSASR 1033
>Q1KKW7:SKAP1_FUGRU Src kinase-associated phosphoprotein 1 - Fugu rubripes (Japanese| pufferfish) (Takifugu rubripes) Length = 363 Score = 32.7 bits (73), Expect = 1.8 Identities = 40/158 (25%), Positives = 66/158 (41%), Gaps = 21/158 (13%) Frame = +3 Query: 45 ASLWRAVMGTGAPSASADATDGI-EFWREPE-----------RGGWLDKQGE----YIKT 176 +SL R+ A AS + DGI E++ + + G+L+K+ + + Sbjct: 79 SSLGRSAQSDDASLASDNQDDGIPEYFGDIPPVAAQDIVNVLKQGYLEKKRKDHSFFGSE 138 Query: 177 WRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPGET 356 W++RW VL +F++ S + I+ S V + FE PG Sbjct: 139 WQKRWCVL-NNLVFYYFGSDKDKQQKGSFYISDYSVQLVTNLRKDSRKTSCFEFFAPGRR 197 Query: 357 MY-FVADSDKEKEDWINSIGRSIVQHSRSMT----DDE 455 + F A S +E ++W++ I IV S T DDE Sbjct: 198 PFQFTAGSPQEAKEWVDQI--KIVLRDLSSTVIPVDDE 233
>P58069:RASA2_MOUSE Ras GTPase-activating protein 2 - Mus musculus (Mouse)| Length = 848 Score = 32.7 bits (73), Expect = 1.8 Identities = 27/95 (28%), Positives = 47/95 (49%), Gaps = 6/95 (6%) Frame = +3 Query: 171 KTWRRRWFVLKQGKLFWF----KDSTVTRASVPRGVIAVASCLTVKGAED-VLNRKFAFE 335 K +++RWF L +L + KD+ T I V + L V+ E+ N+K F+ Sbjct: 624 KNFKKRWFCLTSRELTYHRQQGKDAIYT--------IPVKNILAVEKLEEGSFNKKNMFQ 675 Query: 336 LSTPGETMYFVADSDKEKEDWINSIGR-SIVQHSR 437 + +T+Y A++ E +WI+ + R S H+R Sbjct: 676 VIHTEKTLYIQANNCVEANEWIDVLCRVSRCNHNR 710
>Q8U3N5:PUR2_PYRFU Phosphoribosylamine--glycine ligase - Pyrococcus furiosus| Length = 439 Score = 32.7 bits (73), Expect = 1.8 Identities = 27/105 (25%), Positives = 49/105 (46%), Gaps = 5/105 (4%) Frame = +3 Query: 147 LDKQGEYIKTWRRRW-FVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRK 323 ++K E+ + W+ + F+ + L ++ V A RG+ AV T + A N+ Sbjct: 53 VEKVVEFAEKWKVDFAFIGPEAPL----EAGVVNALEERGIPAVGP--TKEAARLETNKA 106 Query: 324 FAFEL----STPGETMYFVADSDKEKEDWINSIGRSIVQHSRSMT 446 +A E PG ++ V D KE ++WI+ G+ +V +T Sbjct: 107 WAREFMERNKIPGRKLFRVFDDPKEMKEWIDEFGKPVVVKPLGLT 151
>Q08942:NRKA_TRYBB Putative serine/threonine-protein kinase A - Trypanosoma brucei| brucei Length = 431 Score = 32.7 bits (73), Expect = 1.8 Identities = 26/89 (29%), Positives = 44/89 (49%), Gaps = 5/89 (5%) Frame = +3 Query: 171 KTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGA----EDVLNRKFAFEL 338 K+W+ R+ + +G+L D + P+G+ + V+GA R F F L Sbjct: 347 KSWKPRFLQIVRGQLILTDDE---EGNNPKGL----NLEQVQGACPVPHSTAKRDFVFAL 399 Query: 339 STPG-ETMYFVADSDKEKEDWINSIGRSI 422 +T G + M+F A S + E W+++I R I Sbjct: 400 NTVGGKGMWFQAVSHGDMEMWVHAIQRGI 428
>Q5RAB8:FARP1_PONPY FERM, RhoGEF and pleckstrin domain-containing protein 1 - Pongo| pygmaeus (Orangutan) Length = 1045 Score = 32.7 bits (73), Expect = 1.8 Identities = 22/89 (24%), Positives = 39/89 (43%), Gaps = 2/89 (2%) Frame = +3 Query: 177 WRRRWFVLKQGKLFWFKDSTVTR--ASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTPG 350 W++ W V LF++K AS+P + LT+ + +++ + F+L Sbjct: 949 WQKLWVVFTNFCLFFYKSHQDNHPLASLP----LLGYSLTIPTESENIHKDYVFKLHFKS 1004 Query: 351 ETMYFVADSDKEKEDWINSIGRSIVQHSR 437 YF A+S+ E W+ I + SR Sbjct: 1005 HVYYFRAESEYTFERWMEVIRSATSSASR 1033
>O43150:DDEF2_HUMAN Development and differentiation-enhancing factor 2 - Homo sapiens| (Human) Length = 1006 Score = 32.7 bits (73), Expect = 1.8 Identities = 33/132 (25%), Positives = 62/132 (46%), Gaps = 1/132 (0%) Frame = +3 Query: 132 ERGGWLDKQGEYI-KTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAED 308 ER G L K+ + I K W++R +K G F + A+ P + + +C E+ Sbjct: 307 ERNGSLYKKSDGIRKVWQKRKCSVKNG----FLTISHGTANRPPAKLNLLTCQVKTNPEE 362 Query: 309 VLNRKFAFELSTPGETMYFVADSDKEKEDWINSIGRSIVQHSRSMTDDEIVDYDSGHPAT 488 K F+L + T +F A+ ++E + W+ S++Q+S+ ++ + + G T Sbjct: 363 ----KKCFDLISHDRTYHFQAEDEQECQIWM-----SVLQNSK---EEALNNAFKGDDNT 410 Query: 489 GRKS*VRRLIGE 524 G + V+ L E Sbjct: 411 GENNIVQELTKE 422
>P08487:PLCG1_BOVIN 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 -| Bos taurus (Bovine) Length = 1291 Score = 32.3 bits (72), Expect = 2.4 Identities = 20/60 (33%), Positives = 29/60 (48%), Gaps = 3/60 (5%) Frame = +3 Query: 258 RGVIAVASCLTVKGAEDVLNRKFAFELSTPGE---TMYFVADSDKEKEDWINSIGRSIVQ 428 RGV+ V +C E NR F F +S ++ ADS +E +DW+ I R + Q Sbjct: 873 RGVLDVPACQIAVRPEGKNNRLFVFSISMASVAHWSLDVAADSQEELQDWVKKI-REVAQ 931
>Q92349:MUG79_SCHPO Meiotically up-regulated gene 79 protein - Schizosaccharomyces pombe| (Fission yeast) Length = 1318 Score = 32.3 bits (72), Expect = 2.4 Identities = 22/86 (25%), Positives = 38/86 (44%), Gaps = 8/86 (9%) Frame = +3 Query: 177 WRRRWFVLKQGKLFWFKD-----STVTRASVPRGVIAVASCLTVKGAEDVL--NRKFAFE 335 W++++ ++ GKL ++K + + S + SCL + NR F Sbjct: 1068 WKKKYCIVDSGKLIFYKSDHLDPNACSNVSPIHREFGLQSCLASPNLPPSINSNRNNVFY 1127 Query: 336 LSTPGETMY-FVADSDKEKEDWINSI 410 L+ PG Y F A S +WI+S+ Sbjct: 1128 LNIPGNECYLFEAPSVLAMNEWIHSL 1153
>P35568:IRS1_HUMAN Insulin receptor substrate 1 - Homo sapiens (Human)| Length = 1242 Score = 32.3 bits (72), Expect = 2.4 Identities = 28/107 (26%), Positives = 50/107 (46%), Gaps = 13/107 (12%) Frame = +3 Query: 129 PERGGWLD-KQGEYI---KTWRRRWFVLKQG-------KLFWFKDSTVTR--ASVPRGVI 269 PE G+ D ++ Y+ K+ +R+FVL+ +L ++++ R +S P+ I Sbjct: 5 PESDGFSDVRKVGYLRKPKSMHKRFFVLRAASEAGGPARLEYYENEKKWRHKSSAPKRSI 64 Query: 270 AVASCLTVKGAEDVLNRKFAFELSTPGETMYFVADSDKEKEDWINSI 410 + SC + D N K L T E ADS+ E++ W ++ Sbjct: 65 PLESCFNINKRADSKN-KHLVALYTRDEHFAIAADSEAEQDSWYQAL 110
>Q28224:IRS1_CERAE Insulin receptor substrate 1 - Cercopithecus aethiops (Green| monkey) (Grivet) Length = 1251 Score = 32.3 bits (72), Expect = 2.4 Identities = 28/107 (26%), Positives = 50/107 (46%), Gaps = 13/107 (12%) Frame = +3 Query: 129 PERGGWLD-KQGEYI---KTWRRRWFVLKQG-------KLFWFKDSTVTR--ASVPRGVI 269 PE G+ D ++ Y+ K+ +R+FVL+ +L ++++ R +S P+ I Sbjct: 5 PESDGFSDVRKVGYLRKPKSMHKRFFVLRAASETGDPARLEYYENEKKWRHKSSAPKRSI 64 Query: 270 AVASCLTVKGAEDVLNRKFAFELSTPGETMYFVADSDKEKEDWINSI 410 + SC + D N K L T E ADS+ E++ W ++ Sbjct: 65 PLESCFNINKRADSKN-KHLVALYTRDEHFAIAADSEAEQDSWYQAL 110
>Q91VS8:FARP2_MOUSE FERM, RhoGEF and pleckstrin domain-containing protein 2 - Mus| musculus (Mouse) Length = 1065 Score = 32.3 bits (72), Expect = 2.4 Identities = 26/113 (23%), Positives = 50/113 (44%), Gaps = 4/113 (3%) Frame = +3 Query: 126 EPERGGWLDKQGEYIKTWRRRWFVLKQGKLFWFK--DSTVTRASVPRGVIAVASCLTVKG 299 E + G+L ++ + W++ W V LF++K AS+P + +++ Sbjct: 930 ENQLSGYLLRKFKNSNGWQKLWVVFTNFCLFFYKTHQDDYPLASLP----LLGYSVSLPR 985 Query: 300 AEDVLNRKFAFELSTPGETMYFVADSDKEKEDWINSIGRSIVQHSR--SMTDD 452 D +++ + F+L +F A+S E W++ I R+ R S T D Sbjct: 986 EADSIHKDYVFKLQFKSHVYFFRAESKYTFERWMDVIKRASSSPGRPPSFTQD 1038
>Q9SE83:DRP2A_ARATH Dynamin-2A - Arabidopsis thaliana (Mouse-ear cress)| Length = 914 Score = 32.3 bits (72), Expect = 2.4 Identities = 31/122 (25%), Positives = 45/122 (36%), Gaps = 28/122 (22%) Frame = +3 Query: 141 GWLDKQGEYIKTWRRRWFVL--KQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVL 314 G+L K+ W RRWFVL K GKL + K RG I + C + ED + Sbjct: 577 GYLMKKSAKTNGWSRRWFVLNEKTGKLGYTKKQEERNF---RGTITLEECTIEEIPEDEV 633 Query: 315 NRK-------------------FAFELSTPGET-------MYFVADSDKEKEDWINSIGR 416 + F P +T + A+S +K +WIN + + Sbjct: 634 EKSKSSKDKKANGPDSKGPGLVFKITCKVPYKTVLKAHNALVLKAESVVDKNEWINKLQK 693 Query: 417 SI 422 I Sbjct: 694 VI 695
>Q7SIG6:DDEF2_MOUSE Development and differentiation-enhancing factor 2 - Mus musculus| (Mouse) Length = 958 Score = 32.3 bits (72), Expect = 2.4 Identities = 33/132 (25%), Positives = 62/132 (46%), Gaps = 1/132 (0%) Frame = +3 Query: 132 ERGGWLDKQGEYI-KTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAED 308 ER G L K+ + I K W++R +K G F + A+ P + + +C E+ Sbjct: 310 ERNGNLYKKSDGIRKVWQKRKCSVKNG----FLTISHGTANRPPAKLNLLTCQVKTNPEE 365 Query: 309 VLNRKFAFELSTPGETMYFVADSDKEKEDWINSIGRSIVQHSRSMTDDEIVDYDSGHPAT 488 K F+L + T +F A+ ++E + W+ S++Q+S+ ++ + + G T Sbjct: 366 ----KKCFDLISHDRTYHFQAEDEQECQIWM-----SVLQNSK---EEALNNAFKGDDNT 413 Query: 489 GRKS*VRRLIGE 524 G + V+ L E Sbjct: 414 GENNIVQELTKE 425
>O94452:MCP1_SCHPO Meiotic coiled-coil protein 1 - Schizosaccharomyces pombe (Fission| yeast) Length = 661 Score = 32.3 bits (72), Expect = 2.4 Identities = 27/96 (28%), Positives = 40/96 (41%), Gaps = 3/96 (3%) Frame = -1 Query: 340 ESSKANLRLSTSSAPLTVRQEATAMTPRGTDARVTVES---LNQKSFPCLSTNHRRRHVL 170 +S + LRL++ PL R M + D R +S + + S CL NH + + L Sbjct: 452 KSIRFPLRLASHEEPLIDR-----MVNQSPDTRSVSKSKRLVRETSSGCLFKNHSKSNTL 506 Query: 169 MYSPCLSSHPPRSGSRQNSMPSVASADADGAPVPIT 62 P R GSR S DA + +P+T Sbjct: 507 S--------PRRKGSRHGPREPCLSPDASSSSIPVT 534
>Q5R8M5:URP1_PONPY Unc-112-related protein 1 - Pongo pygmaeus (Orangutan)| Length = 677 Score = 31.6 bits (70), Expect = 4.0 Identities = 20/82 (24%), Positives = 36/82 (43%), Gaps = 4/82 (4%) Frame = +3 Query: 168 IKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFELSTP 347 +K +++ WFV K + +FK+ + + P + + C V +V RKF +L P Sbjct: 386 LKAFKQYWFVFKDTSIAYFKNKELEQGE-PLEKLNLRGCEVVPNV-NVAERKFGIKLLIP 443 Query: 348 ----GETMYFVADSDKEKEDWI 401 MY D + + W+ Sbjct: 444 VADGMNEMYLRCDHENQYAQWM 465
>Q9QUH6:SYGP1_RAT Ras GTPase-activating protein SynGAP - Rattus norvegicus (Rat)| Length = 1308 Score = 31.6 bits (70), Expect = 4.0 Identities = 12/38 (31%), Positives = 23/38 (60%) Frame = +3 Query: 309 VLNRKFAFELSTPGETMYFVADSDKEKEDWINSIGRSI 422 +L ++F FE++T T F S E++ WI ++ R++ Sbjct: 213 ILGQEFCFEVTTSSGTKCFACRSAAERDKWIENLQRAV 250
>Q96PV0:SYGP1_HUMAN Ras GTPase-activating protein SynGAP - Homo sapiens (Human)| Length = 1343 Score = 31.6 bits (70), Expect = 4.0 Identities = 12/38 (31%), Positives = 23/38 (60%) Frame = +3 Query: 309 VLNRKFAFELSTPGETMYFVADSDKEKEDWINSIGRSI 422 +L ++F FE++T T F S E++ WI ++ R++ Sbjct: 213 ILGQEFCFEVTTSSGTKCFACRSAAERDKWIENLQRAV 250
>Q86UU1:PHLB1_HUMAN Pleckstrin homology-like domain family B member 1 - Homo sapiens| (Human) Length = 1377 Score = 31.6 bits (70), Expect = 4.0 Identities = 18/45 (40%), Positives = 27/45 (60%), Gaps = 2/45 (4%) Frame = +3 Query: 141 GWLDKQGEYIKTWRRRWFVLKQGK--LFWFKDSTVTRASVPRGVI 269 G+L K G IK+W++RWFV + K L ++ D T+ +GVI Sbjct: 1261 GYLVKMGGKIKSWKKRWFVFDRLKRTLSYYVDKHETKL---KGVI 1302
>Q5F3S2:PKHB2_CHICK Pleckstrin homology domain-containing family B member 2 - Gallus| gallus (Chicken) Length = 224 Score = 31.2 bits (69), Expect = 5.2 Identities = 11/33 (33%), Positives = 20/33 (60%), Gaps = 1/33 (3%) Frame = +3 Query: 135 RGGWLDKQGEYIKTWRRRWFVL-KQGKLFWFKD 230 + GWL +Q ++ W++ WF L G+L ++ D Sbjct: 5 KSGWLLRQSTILRRWKKNWFDLWSDGRLIFYDD 37
>P35845:OSH1_YEAST Oxysterol-binding protein homolog 1 - Saccharomyces cerevisiae| (Baker's yeast) Length = 1188 Score = 31.2 bits (69), Expect = 5.2 Identities = 17/53 (32%), Positives = 30/53 (56%), Gaps = 1/53 (1%) Frame = +3 Query: 129 PERGGWLDKQGEYIKTWRRRWFVL-KQGKLFWFKDSTVTRASVPRGVIAVASC 284 P G+L K + + ++ RWF+L GKL ++ D T+ + RG + ++SC Sbjct: 282 PTYKGYLKKWTNFAQGYKLRWFILSSDGKLSYYIDQADTK-NACRGSLNMSSC 333
>Q9DBS9:OSBL3_MOUSE Oxysterol-binding protein-related protein 3 - Mus musculus (Mouse)| Length = 855 Score = 31.2 bits (69), Expect = 5.2 Identities = 30/135 (22%), Positives = 60/135 (44%), Gaps = 7/135 (5%) Frame = +3 Query: 75 GAPSASADATDGIE----FWREP--ERGGWLDKQGEYIKTWRRRWFVLKQGKLFWFKDST 236 G+ S + +G+ + +EP ++G L K+ +K W +R+F L++G L + K Sbjct: 28 GSRQDSWEVVEGLRGEMTYTQEPPVQKGFLLKKRKWPLKGWHKRFFCLEKGILKYAKSQA 87 Query: 237 VTRASVPRGVIAVA-SCLTVKGAEDVLNRKFAFELSTPGETMYFVADSDKEKEDWINSIG 413 G I V S ++VK + + +L T + S++ ++W++ + Sbjct: 88 DIEREKLHGCIDVGLSVMSVKKSSKCI------DLDTEEHIYHLKVKSEELFDEWVSKL- 140 Query: 414 RSIVQHSRSMTDDEI 458 +H R +EI Sbjct: 141 ----RHHRMYRQNEI 151
>Q69ZL1:FGD6_MOUSE FYVE, RhoGEF and PH domain-containing protein 6 - Mus musculus| (Mouse) Length = 1399 Score = 31.2 bits (69), Expect = 5.2 Identities = 24/96 (25%), Positives = 39/96 (40%), Gaps = 1/96 (1%) Frame = +3 Query: 141 GWLDKQGEYIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNR 320 G+L + K W+ WFV+K L+ + S A + ++ TV +D + Sbjct: 1307 GYLYRSKGSKKPWKHLWFVIKNKVLYTYAASEDVAALESQPLLG----FTVTLVKDENSE 1362 Query: 321 KFAFELSTPGETMY-FVADSDKEKEDWINSIGRSIV 425 F+L G Y F AD + WI++ V Sbjct: 1363 SKVFQLLHKGMVFYVFKADDAHSTQRWIDAFQEGTV 1398
>O94887:FARP2_HUMAN FERM, RhoGEF and pleckstrin domain-containing protein 2 - Homo| sapiens (Human) Length = 1054 Score = 31.2 bits (69), Expect = 5.2 Identities = 27/130 (20%), Positives = 56/130 (43%), Gaps = 2/130 (1%) Frame = +3 Query: 126 EPERGGWLDKQGEYIKTWRRRWFVLKQGKLFWFK--DSTVTRASVPRGVIAVASCLTVKG 299 E + G+L ++ + W++ W V LF++K AS+P + +++ Sbjct: 929 ENQLSGYLLRKFKNSHGWQKLWVVFTNFCLFFYKTHQDDYPLASLP----LLGYSVSIPR 984 Query: 300 AEDVLNRKFAFELSTPGETMYFVADSDKEKEDWINSIGRSIVQHSRSMTDDEIVDYDSGH 479 D +++ + F+L +F A+S E W+ I + R+ + + D Sbjct: 985 EADGIHKDYVFKLQFKSHVYFFRAESKYTFERWMEVIQGASSSAGRAPS----IVQDGPQ 1040 Query: 480 PATGRKS*VR 509 P++G + VR Sbjct: 1041 PSSGLEGMVR 1050
>Q5A950:ATG26_CANAL Sterol 3-beta-glucosyltransferase - Candida albicans (Yeast)| Length = 1513 Score = 31.2 bits (69), Expect = 5.2 Identities = 14/44 (31%), Positives = 24/44 (54%) Frame = +3 Query: 330 FELSTPGETMYFVADSDKEKEDWINSIGRSIVQHSRSMTDDEIV 461 F+L T +T F DS W N+I + I QH+ + ++ E++ Sbjct: 489 FKLVTKKKTYKFSCDSSFSARQWCNNITKLIFQHNNANSNGEVL 532
>Q5BIW4:ALS2_PANTR Alsin - Pan troglodytes (Chimpanzee)| Length = 1657 Score = 31.2 bits (69), Expect = 5.2 Identities = 14/48 (29%), Positives = 28/48 (58%) Frame = +3 Query: 333 ELSTPGETMYFVADSDKEKEDWINSIGRSIVQHSRSMTDDEIVDYDSG 476 +++TP E ++ + +EK W+ +I +++ Q R M+D + Y SG Sbjct: 975 KITTPEEQFTLISSTPQEKTKWLRAISQAVDQALRGMSD--LPPYGSG 1020
>Q96Q42:ALS2_HUMAN Alsin - Homo sapiens (Human)| Length = 1657 Score = 31.2 bits (69), Expect = 5.2 Identities = 14/48 (29%), Positives = 28/48 (58%) Frame = +3 Query: 333 ELSTPGETMYFVADSDKEKEDWINSIGRSIVQHSRSMTDDEIVDYDSG 476 +++TP E ++ + +EK W+ +I +++ Q R M+D + Y SG Sbjct: 975 KITTPEEQFTLISSTPQEKTKWLRAISQAVDQALRGMSD--LPPYGSG 1020
>Q10580:SWAP_CAEEL Protein SWAP - Caenorhabditis elegans| Length = 749 Score = 31.2 bits (69), Expect = 5.3 Identities = 21/64 (32%), Positives = 27/64 (42%) Frame = -1 Query: 427 WTMERPMELIQSSFSLSESATKYMVSPGVESSKANLRLSTSSAPLTVRQEATAMTPRGTD 248 W M +P+E S L+ A VS SS +L LST PL RQ + D Sbjct: 440 WRMYQPIEQNLSPLVLNSPAPPSAVSSPGPSSLMSLNLSTPEPPLNRRQRRRLLDSSRLD 499 Query: 247 ARVT 236 +T Sbjct: 500 ESIT 503
>Q99KN1:ARRD1_MOUSE Arrestin domain-containing protein 1 - Mus musculus (Mouse)| Length = 434 Score = 31.2 bits (69), Expect = 5.3 Identities = 34/116 (29%), Positives = 49/116 (42%), Gaps = 7/116 (6%) Frame = -1 Query: 385 SLSESATKYMVSPGVESSKANLRLSTSSAPLTVRQEATAMTPRGTD-ARVTVESLNQKS- 212 +++ + T PG ESS L L SAP EA A P +D ++ +S +Q+ Sbjct: 283 NIAVNQTPLSPCPGRESSPGTLSLVVPSAPPQEEAEAVASGPHFSDPVSLSTKSHSQQQP 342 Query: 211 ----FPCLSTNHRRRHVLMYSPCLSS-HPPRSGSRQNSMPSVASADADGAPVPITA 59 +S V + SP S HPP S ++P A A PVP T+ Sbjct: 343 LSAPLGSVSVTTTEPWVQVGSPARHSLHPPLCISIGATVPYFAEGSA--GPVPTTS 396
>Q499P8:CP058_RAT UPF0420 protein C16orf58 homolog - Rattus norvegicus (Rat)| Length = 466 Score = 30.8 bits (68), Expect = 6.9 Identities = 19/59 (32%), Positives = 26/59 (44%), Gaps = 5/59 (8%) Frame = +3 Query: 39 LMASLWRAVMGTGAPSASADATDGIEFWREPERGGW-----LDKQGEYIKTWRRRWFVL 200 L A L G+GAP + + A DG W +R GW + K G++ R W L Sbjct: 7 LRAPLCTEQFGSGAPRSCSAAADGSLQWDRAQRWGWFSRASITKPGQHEGGGRGPWAAL 65
>O75689:CENA1_HUMAN Centaurin-alpha 1 - Homo sapiens (Human)| Length = 374 Score = 30.8 bits (68), Expect = 6.9 Identities = 21/105 (20%), Positives = 47/105 (44%), Gaps = 11/105 (10%) Frame = +3 Query: 141 GWLDKQG-EYIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLN 317 G+++K G + + +R+RWF + +L +FKD A RG + + S + VL+ Sbjct: 257 GYMEKTGPKQTEGFRKRWFTMDDRRLMYFKDPLDAFA---RGEVFIGS---KESGYTVLH 310 Query: 318 R----------KFAFELSTPGETMYFVADSDKEKEDWINSIGRSI 422 + TP F +++ ++ +W+ + +++ Sbjct: 311 GFPPSTQGHHWPHGITIVTPDRKFLFACETESDQREWVAAFQKAV 355
>Q8NJS1:ATG26_LEPMC Sterol 3-beta-glucosyltransferase - Leptosphaeria maculans| (Blackleg fungus) Length = 1456 Score = 30.8 bits (68), Expect = 6.9 Identities = 24/96 (25%), Positives = 43/96 (44%), Gaps = 2/96 (2%) Frame = +3 Query: 141 GWLDKQGEYIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVL-- 314 G+L K+G R WF+L+ L ++ + PR I + ++ + E Sbjct: 292 GYLSKRGR--SKHNRYWFILRGDVLAYYTNPA--ELYFPRNRINLQYAISAEVLEPKRKG 347 Query: 315 NRKFAFELSTPGETMYFVADSDKEKEDWINSIGRSI 422 + + +F ++T T F ADS +W+ SI + I Sbjct: 348 DEETSFVVTTDERTYQFKADSVASAREWVKSIQKVI 383
>O97627:ARBK1_DIDMA Beta-adrenergic receptor kinase 1 - Didelphis marsupialis| virginiana (North American opossum) Length = 689 Score = 30.8 bits (68), Expect = 6.9 Identities = 20/87 (22%), Positives = 38/87 (43%), Gaps = 1/87 (1%) Frame = +3 Query: 141 GWLDKQGE-YIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLN 317 G++ K G ++ W+RR+F L +L W + P+ ++ + +V+ + + + Sbjct: 563 GYMSKMGNPFLTQWQRRYFYLFPNRLEWRAE-----GEAPQSLLTMEEIQSVEETQ-IKD 616 Query: 318 RKFAFELSTPGETMYFVADSDKEKEDW 398 RK G+ DSD E W Sbjct: 617 RKCILLKIRGGKQFILQCDSDPELVQW 643
>P62592:INT2_SALTI Integrase/recombinase - Salmonella typhi| Length = 337 Score = 30.8 bits (68), Expect = 6.9 Identities = 17/52 (32%), Positives = 25/52 (48%), Gaps = 3/52 (5%) Frame = -1 Query: 631 IISVEDMYQKNLDKHDKDDVEQ*SLQMPPTPH---RSFCSPINRRTYDLRPV 485 ++ MY + + K VEQ + P TPH SF + + R YD+R V Sbjct: 246 VVRRHHMYDQTFQRAFKRAVEQAGITKPATPHTLRHSFATALLRSGYDIRTV 297
>P62591:INT2_PSEAE Integrase/recombinase - Pseudomonas aeruginosa| Length = 337 Score = 30.8 bits (68), Expect = 6.9 Identities = 17/52 (32%), Positives = 25/52 (48%), Gaps = 3/52 (5%) Frame = -1 Query: 631 IISVEDMYQKNLDKHDKDDVEQ*SLQMPPTPH---RSFCSPINRRTYDLRPV 485 ++ MY + + K VEQ + P TPH SF + + R YD+R V Sbjct: 246 VVRRHHMYDQTFQRAFKRAVEQAGITKPATPHTLRHSFATALLRSGYDIRTV 297
>P62590:INT2_ECOLI Integrase/recombinase - Escherichia coli| Length = 337 Score = 30.8 bits (68), Expect = 6.9 Identities = 17/52 (32%), Positives = 25/52 (48%), Gaps = 3/52 (5%) Frame = -1 Query: 631 IISVEDMYQKNLDKHDKDDVEQ*SLQMPPTPH---RSFCSPINRRTYDLRPV 485 ++ MY + + K VEQ + P TPH SF + + R YD+R V Sbjct: 246 VVRRHHMYDQTFQRAFKRAVEQAGITKPATPHTLRHSFATALLRSGYDIRTV 297
>Q13393:PLD1_HUMAN Phospholipase D1 - Homo sapiens (Human)| Length = 1074 Score = 30.4 bits (67), Expect = 8.9 Identities = 20/99 (20%), Positives = 36/99 (36%) Frame = +3 Query: 156 QGEYIKTWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVLNRKFAFE 335 QG W +RW ++K L + K + A V+ V +K + K+ Sbjct: 243 QGRACYRWSKRWLIVKDSFLLYMKPDSGAIAF----VLLVDKEFKIKVGKKETETKYGIR 298 Query: 336 LSTPGETMYFVADSDKEKEDWINSIGRSIVQHSRSMTDD 452 + T+ +S + W +I I +H + D Sbjct: 299 IDNLSRTLILKCNSYRHARWWGGAIEEFIQKHGTNFLKD 337
>P52734:FGD1_MOUSE FYVE, RhoGEF and PH domain-containing protein 1 - Mus musculus| (Mouse) Length = 960 Score = 30.4 bits (67), Expect = 8.9 Identities = 25/109 (22%), Positives = 51/109 (46%), Gaps = 10/109 (9%) Frame = +3 Query: 147 LDKQGEYIK------TWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAE- 305 L K+G +K T + R+ +L +L + V R + V + + V G E Sbjct: 590 LIKEGHILKLSAKNGTTQDRYLILFNDRLLY----CVPRLRLLGQKFTVRARIDVDGMEL 645 Query: 306 ---DVLNRKFAFELSTPGETMYFVADSDKEKEDWINSIGRSIVQHSRSM 443 LN F +S ++ A +++EK+DW+ +I ++++H +++ Sbjct: 646 KESSNLNMPRTFLVSGKQRSLELQARTEEEKKDWVQAINSTLLKHEQTL 694
>P98174:FGD1_HUMAN FYVE, RhoGEF and PH domain-containing protein 1 - Homo sapiens| (Human) Length = 961 Score = 30.4 bits (67), Expect = 8.9 Identities = 25/109 (22%), Positives = 52/109 (47%), Gaps = 10/109 (9%) Frame = +3 Query: 147 LDKQGEYIK------TWRRRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAE- 305 L K+G +K T + R+ +L +L + V R + +V + + V G E Sbjct: 591 LIKEGHILKLSAKNGTTQDRYLILFNDRLLY----CVPRLRLLGQKFSVRARIDVDGMEL 646 Query: 306 ---DVLNRKFAFELSTPGETMYFVADSDKEKEDWINSIGRSIVQHSRSM 443 LN F +S ++ A +++EK+DW+ +I ++++H +++ Sbjct: 647 KESSNLNLPRTFLVSGKQRSLELQARTEEEKKDWVQAINSTLLKHEQTL 695
>Q9Y751:ATG26_PICPA Sterol 3-beta-glucosyltransferase - Pichia pastoris (Yeast)| Length = 1211 Score = 30.4 bits (67), Expect = 8.9 Identities = 25/82 (30%), Positives = 35/82 (42%), Gaps = 2/82 (2%) Frame = +3 Query: 183 RRWFVLKQGKLFWFKDSTVTRASVPRGVIAVASCLTVKGAEDVL--NRKFAFELSTPGET 356 RRW VLK + +ST P I + L V+ + L N+ F+L T T Sbjct: 267 RRWAVLKGNYFRLYANST--ERYFPSLNIDLRFLLKVELSNPNLEENKPTVFKLITEART 324 Query: 357 MYFVADSDKEKEDWINSIGRSI 422 YF ADS W+ + + I Sbjct: 325 HYFQADSLDNARSWVTDLRKHI 346 Database: uniprot_sprot.fasta.out Posted date: Jul 19, 2007 5:58 PM Number of letters in database: 100,686,439 Number of sequences in database: 274,295 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 274295 Number of Hits to DB: 110,886,896 Number of extensions: 2419878 Number of successful extensions: 7870 Number of sequences better than 10.0: 221 Number of HSP's gapped: 7788 Number of HSP's successfully gapped: 237 Length of query: 278 Length of database: 100,686,439 Length adjustment: 112 Effective length of query: 166 Effective length of database: 69,965,399 Effective search space: 11614256234 Effective search space used: 11614256234 Neighboring words threshold: 12 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
