Clone Name	FLbaf67j12
Clone Library Name	barley_pub

---

No.	Definition	Score (bits)	E Value
1	P09379:GYP7_YARLI GTPase-activating protein GYP7 - Yarrowia lipo...	118	1e-25
2	P48365:GYP7_YEAST GTPase-activating protein GYP7 - Saccharomyces...	108	7e-23
3	Q6FWI1:GYP7_CANGA GTPase-activating protein GYP7 - Candida glabr...	108	7e-23
4	Q8TC07:TBC15_HUMAN TBC1 domain family member 15 - Homo sapiens (...	108	1e-22
5	Q6BU76:GYP7_DEBHA GTPase-activating protein GYP7 - Debaryomyces ...	108	1e-22
6	Q9CXF4:TBC15_MOUSE TBC1 domain family member 15 - Mus musculus (...	106	5e-22
7	Q3MII6:TBC25_HUMAN TBC1 domain family member 25 - Homo sapiens (...	102	9e-21
8	A1A5B6:TBC25_MOUSE TBC1 domain family member 25 - Mus musculus (...	100	2e-20
9	Q8BYH7:TBC17_MOUSE TBC1 domain family member 17 - Mus musculus (...	97	2e-19
10	Q9HA65:TBC17_HUMAN TBC1 domain family member 17 - Homo sapiens (...	97	3e-19
11	Q8TBP0:TBC16_HUMAN TBC1 domain family member 16 - Homo sapiens (...	84	3e-15
12	Q8BPQ7:RUTB2_MOUSE RUN and TBC1 domain-containing protein 2 - Mu...	75	1e-12
13	Q2NKQ1:RUTB2_HUMAN RUN and TBC1 domain-containing protein 2 - Ho...	74	3e-12
14	Q80U12:RUTB1_MOUSE RUN and TBC1 domain-containing protein 1 - Mu...	73	6e-12
15	O43147:RUTB1_HUMAN RUN and TBC1 domain-containing protein 1 - Ho...	72	1e-11
16	Q8R3D1:TBC13_MOUSE TBC1 domain family member 13 - Mus musculus (...	65	1e-09
17	Q755I4:GYP5_ASHGO GTPase-activating protein GYP5 - Ashbya gossyp...	62	8e-09
18	Q8IV04:TB10C_HUMAN Carabin - Homo sapiens (Human)	62	1e-08
19	Q08484:GYP1_YEAST GTPase-activating protein GYP1 - Saccharomyces...	61	2e-08
20	Q8C9V1:TB10C_MOUSE Carabin - Mus musculus (Mouse)	60	3e-08
21	Q95LL3:TB22B_MACFA TBC1 domain family member 22B - Macaca fascic...	60	5e-08
22	Q9NU19:TB22B_HUMAN TBC1 domain family member 22B - Homo sapiens ...	60	5e-08
23	Q8R5A6:TB22A_MOUSE TBC1 domain family member 22A - Mus musculus ...	57	4e-07
24	Q95KI1:TB22A_MACFA TBC1 domain family member 22A - Macaca fascic...	56	8e-07
25	Q8WUA7:TB22A_HUMAN TBC1 domain family member 22A - Homo sapiens ...	55	1e-06
26	Q80XC3:US6NL_MOUSE USP6 N-terminal-like protein - Mus musculus (...	54	2e-06
27	Q92738:US6NL_HUMAN USP6 N-terminal-like protein - Homo sapiens (...	54	3e-06
28	Q9BXI6:TB10A_HUMAN TBC1 domain family member 10A - Homo sapiens ...	53	5e-06
29	P58802:TB10A_MOUSE TBC1 domain family member 10A - Mus musculus ...	53	6e-06
30	Q12344:GYP5_YEAST GTPase-activating protein GYP5 - Saccharomyces...	52	8e-06
31	O60347:TBC12_HUMAN TBC1 domain family member 12 - Homo sapiens (...	51	2e-05
32	Q8BYJ6:TBCD4_MOUSE TBC1 domain family member 4 - Mus musculus (M...	50	4e-05
33	O60343:TBCD4_HUMAN TBC1 domain family member 4 - Homo sapiens (H...	50	4e-05
34	Q86TI0:TBCD1_HUMAN TBC1 domain family member 1 - Homo sapiens (H...	50	5e-05
35	Q60949:TBCD1_MOUSE TBC1 domain family member 1 - Mus musculus (M...	49	7e-05
36	O97790:TBCD1_BOVIN TBC1 domain family member 1 - Bos taurus (Bov...	49	9e-05
37	Q6PBU5:GRPT1_DANRE Growth hormone regulated TBC protein 1 - Dani...	49	9e-05
38	Q9BYX2:TBCD2_HUMAN TBC1 domain family member 2 - Homo sapiens (H...	48	2e-04
39	Q6GL87:GRPT1_XENTR Growth hormone regulated TBC protein 1 - Xeno...	48	2e-04
40	Q6GLZ0:GRTP1_XENLA Growth hormone regulated TBC protein 1 - Xeno...	47	3e-04
41	Q09445:YQ01_CAEEL Uncharacterized protein C04A2.1 - Caenorhabdit...	47	3e-04
42	Q9Z1A9:TBCD8_MOUSE TBC1 domain family member 8 - Mus musculus (M...	47	3e-04
43	Q8IYX1:TBC21_HUMAN TBC1 domain family member 21 - Homo sapiens (...	47	3e-04
44	Q8BM85:TBCK_MOUSE TBC domain-containing protein kinase-like prot...	46	8e-04
45	Q8TEA7:TBCK_HUMAN TBC domain-containing protein kinase-like prot...	46	8e-04
46	Q5F361:TBCK_CHICK TBC domain-containing protein kinase-like prot...	46	8e-04
47	Q4QQU7:GRPT1_RAT Growth hormone-regulated TBC protein 1 - Rattus...	46	8e-04
48	O95759:TBCD8_HUMAN TBC1 domain family member 8 - Homo sapiens (H...	45	0.001
49	Q9P2M4:TBC14_HUMAN TBC1 domain family member 14 - Homo sapiens (...	44	0.003
50	Q5TC63:GRTP1_HUMAN Growth hormone-regulated TBC protein 1 - Homo...	44	0.003
51	Q8CGA2:TBC14_MOUSE TBC1 domain family member 14 - Mus musculus (...	44	0.004
52	Q92609:TBCD5_HUMAN TBC1 domain family member 5 - Homo sapiens (H...	43	0.007
53	P48566:GYP3_YEAST GTPase-activating protein GYP3 - Saccharomyces...	43	0.007
54	Q8IZP1:TBCD3_HUMAN TBC1 domain family member 3 - Homo sapiens (H...	42	0.009
55	P35125:UBP6_HUMAN Ubiquitin carboxyl-terminal hydrolase 6 - Homo...	42	0.011
56	Q12317:MSB4_YEAST GTPase-activating protein MSB4 - Saccharomyces...	42	0.011
57	Q3UYK3:TBCD9_MOUSE TBC1 domain family member 9 - Mus musculus (M...	42	0.015
58	Q6ZT07:TBCD9_HUMAN TBC1 domain family member 9 - Homo sapiens (H...	42	0.015
59	Q80XQ2:TBCD5_MOUSE TBC1 domain family member 5 - Mus musculus (M...	42	0.015
60	O94661:GYP10_SCHPO GTPase-activating protein gyp10 - Schizosacch...	42	0.015
61	P53258:GYP2_YEAST GTPase-activating protein GYP2 - Saccharomyces...	41	0.025
62	Q09830:YAD4_SCHPO Uncharacterized protein C4G8.04 - Schizosaccha...	40	0.033
63	Q96CN4:EVI5L_HUMAN EVI5-like protein - Homo sapiens (Human)	40	0.043
64	Q5SVR0:TBC9B_MOUSE TBC1 domain family member 9B - Mus musculus (...	39	0.073
65	Q66K14:TBC9B_HUMAN TBC1 domain family member 9B - Homo sapiens (...	39	0.073
66	O60447:EVI5_HUMAN Ecotropic viral integration site 5 protein hom...	39	0.073
67	P36618:CDC16_SCHPO Cell division control protein 16 - Schizosacc...	39	0.12
68	Q10496:YDG9_SCHPO Uncharacterized protein C26F1.09 - Schizosacch...	38	0.16
69	Q9D3N8:GRTP1_MOUSE Growth hormone-regulated TBC protein 1 - Mus ...	38	0.16
70	Q94F62:BAK1_ARATH BRASSINOSTEROID INSENSITIVE 1-associated recep...	37	0.47
71	Q04322:YM52_YEAST Uncharacterized protein YMR192W - Saccharomyce...	35	1.8
72	O18784:TRPC1_BOVIN Short transient receptor potential channel 1 ...	34	3.1
73	P98166:VLDLR_RAT Very low-density lipoprotein receptor precursor...	32	8.9
74	P98156:VLDLR_MOUSE Very low-density lipoprotein receptor precurs...	32	8.9

---

>P09379:GYP7_YARLI GTPase-activating protein GYP7 - Yarrowia lipolytica (Candida|
            lipolytica)
          Length = 730
 Score =  118 bits (295), Expect = 1e-25
 Identities = 61/193 (31%), Positives = 106/193 (54%)
 Frame = +2

Query: 1280 HAARLVALLEAYALYDPEIGYCQGMSDLLSPIIAVMKEDHEAFWCFVGFMKKARHNFRLD 1459
            H  +L  +L  Y  ++  +GY QGMSDLLSP+  V+++D  AFW F  FM++   N+  D
Sbjct: 495  HLIQLRDMLITYNQHNKNLGYVQGMSDLLSPLYVVLQDDTLAFWAFSAFMERMERNYLRD 554

Query: 1460 EVGIRRQLKTVSQIIKRKDSHLYRHLQKLQAKDCFFVYRMVLVLFRRELTFEQTLCLWEV 1639
            + G+R QL  +  +++     LY+HL+K ++ + FF +RM+LV F+REL ++  L LWEV
Sbjct: 555  QSGMRNQLLCLDHLVQFMLPSLYKHLEKTESTNLFFFFRMLLVWFKRELLWDDVLRLWEV 614

Query: 1640 MWADQAAVRAGIGRSTWGRIRLHAPPTDDLLLYAIAACVLQRRKLIIERYSSMDEILREC 1819
            +W D                      +   +L+   A + + + ++I+  +  DEIL+  
Sbjct: 615  LWTDYL--------------------SSQFVLFVCLAILDKHKDVMIDHLAGFDEILKYM 654

Query: 1820 HSMAGQLDVWRLL 1858
            + ++  +D+  LL
Sbjct: 655  NELSMTIDLDELL 667



 Score = 55.5 bits (132), Expect = 1e-06
 Identities = 29/93 (31%), Positives = 50/93 (53%), Gaps = 1/93 (1%)
 Frame = +2

Query: 437 SDRG-EIKSPWSRRKRKQALSCQNWSRLFSVNGKFRDGGRKFLKKVRSGGIEPGIRAEVW 613
           SD G E+    +  +R+  +S   W+  F  NG+      +  +++  GG+ P +R E W
Sbjct: 339 SDEGFELIDAENNPQRRNEVSLAEWNAFFDYNGRLIVTVNEVKERIFHGGLAPAVRPEGW 398

Query: 614 PFLLGVYDLNSSEEERNIIKTKKRNEYEKLSRK 712
            FLLGVY  +S+  ER  + +K R +Y +L ++
Sbjct: 399 LFLLGVYPWDSTAAERKELVSKLRVDYNRLKKE 431

---

>P48365:GYP7_YEAST GTPase-activating protein GYP7 - Saccharomyces cerevisiae (Baker's|
            yeast)
          Length = 746

 Score =  108 bits (271), Expect = 7e-23
 Identities = 58/188 (30%), Positives = 94/188 (50%)
 Frame = +2

Query: 1280 HAARLVALLEAYALYDPEIGYCQGMSDLLSPIIAVMKEDHEAFWCFVGFMKKARHNFRLD 1459
            H   L  +L  Y +Y+  +GY QGM+DLLSPI  +MKE+ + FWCF  FM     NF  D
Sbjct: 509  HLIHLQNILITYNVYNTNLGYVQGMTDLLSPIYVIMKEEWKTFWCFTHFMDIMERNFLRD 568

Query: 1460 EVGIRRQLKTVSQIIKRKDSHLYRHLQKLQAKDCFFVYRMVLVLFRRELTFEQTLCLWEV 1639
            + GI  Q+ T+ ++++     L  HL K  + + FF +RM+LV F+RE   E  + +WE 
Sbjct: 569  QSGIHEQMLTLVELVQLMLPELSEHLNKCDSGNLFFCFRMLLVWFKREFEMEDIMHIWEN 628

Query: 1640 MWADQAAVRAGIGRSTWGRIRLHAPPTDDLLLYAIAACVLQRRKLIIERYSSMDEILREC 1819
             W                        +    L+ + A + +  + I++  +  D+IL+  
Sbjct: 629  FWTFYY--------------------SSQFQLFFMLAILQKNSQAILQHLNQFDQILKFF 668

Query: 1820 HSMAGQLD 1843
            + + G+LD
Sbjct: 669  NELNGKLD 676



 Score = 38.1 bits (87), Expect = 0.16
 Identities = 25/78 (32%), Positives = 42/78 (53%), Gaps = 2/78 (2%)
 Frame = +2

Query: 476 KRKQALSCQNWSRLFSVN-GKFRDGGRKFLKKVRSGGIE-PGIRAEVWPFLLGVYDLNSS 649
           +R+  L+   W+ L+  N G+ R    +    +  GG+E   +R +VW FLL +Y  +SS
Sbjct: 348 QRQFPLTEAKWNSLWDENDGRLRVTVNEVKDFIFHGGLENDSLRGKVWGFLLEIYPWDSS 407

Query: 650 EEERNIIKTKKRNEYEKL 703
           ++ER  I      EY++L
Sbjct: 408 QDERVQIDQTLAAEYDQL 425

---

>Q6FWI1:GYP7_CANGA GTPase-activating protein GYP7 - Candida glabrata (Yeast) (Torulopsis|
            glabrata)
          Length = 745

 Score =  108 bits (271), Expect = 7e-23
 Identities = 46/121 (38%), Positives = 75/121 (61%)
 Frame = +2

Query: 1289 RLVALLEAYALYDPEIGYCQGMSDLLSPIIAVMKEDHEAFWCFVGFMKKARHNFRLDEVG 1468
            +L  +L  Y +++P +GY QGM+DLLSP+  +++++   FWCF  FM++   NF  D+ G
Sbjct: 502  KLADILTTYNIFNPNLGYVQGMTDLLSPLYYIIRDEETTFWCFTNFMERMERNFLRDQSG 561

Query: 1469 IRRQLKTVSQIIKRKDSHLYRHLQKLQAKDCFFVYRMVLVLFRRELTFEQTLCLWEVMWA 1648
            IR Q+  ++ + +     L  HLQK  + D FF +RM+LV F+RE  ++    +WEV + 
Sbjct: 562  IRDQMLALTDLCQLMLPRLSAHLQKCDSSDLFFCFRMLLVWFKREFNYDDIFNIWEVFFT 621

Query: 1649 D 1651
            D
Sbjct: 622  D 622



 Score = 53.9 bits (128), Expect = 3e-06
 Identities = 28/80 (35%), Positives = 44/80 (55%), Gaps = 1/80 (1%)
 Frame = +2

Query: 476 KRKQALSCQNWSRLFSVNGKFRDGGRKFLKKVRSGGI-EPGIRAEVWPFLLGVYDLNSSE 652
           +R   ++ Q W+ LF   G+      +    +  GG+ +   R EVWPFLLGVY  +SSE
Sbjct: 355 ERNHPMTKQKWNSLFDSEGRLTVTVNEVKDYIFHGGLADDATRKEVWPFLLGVYPWDSSE 414

Query: 653 EERNIIKTKKRNEYEKLSRK 712
           +ER  ++    +EY +L +K
Sbjct: 415 DERKQLRKALHDEYMELKQK 434

---

>Q8TC07:TBC15_HUMAN TBC1 domain family member 15 - Homo sapiens (Human)|
          Length = 691

 Score =  108 bits (270), Expect = 1e-22
 Identities = 58/196 (29%), Positives = 103/196 (52%)
 Frame = +2

Query: 1301 LLEAYALYDPEIGYCQGMSDLLSPIIAVMKEDHEAFWCFVGFMKKARHNFRLDEVGIRRQ 1480
            +L  Y +YD ++GY QGMSDLLSP++ VM+ + +AFWCF  +M +   NF     G++ Q
Sbjct: 439  ILMTYCMYDFDLGYVQGMSDLLSPLLYVMENEVDAFWCFASYMDQMHQNFEEQMQGMKTQ 498

Query: 1481 LKTVSQIIKRKDSHLYRHLQKLQAKDCFFVYRMVLVLFRRELTFEQTLCLWEVMWADQAA 1660
            L  +S +++  DS    +L+   +   +F +R +L+ F+RE +F   L LWEVMW +   
Sbjct: 499  LIQLSTLLRLLDSGFCSYLESQDSGYLYFCFRWLLIRFKREFSFLDILRLWEVMWTEL-- 556

Query: 1661 VRAGIGRSTWGRIRLHAPPTDDLLLYAIAACVLQRRKLIIERYSSMDEILRECHSMAGQL 1840
                              P  +  L    A +   ++ I+E++   +EIL+  + ++ ++
Sbjct: 557  ------------------PCTNFHLLLCCAILESEKQQIMEKHYGFNEILKHINELSMKI 598

Query: 1841 DVWRLLDDAHDLVVNL 1888
            DV  +L  A  + + +
Sbjct: 599  DVEDILCKAEAISLQM 614



 Score = 43.5 bits (101), Expect = 0.004
 Identities = 19/76 (25%), Positives = 43/76 (56%)
 Frame = +2

Query: 476 KRKQALSCQNWSRLFSVNGKFRDGGRKFLKKVRSGGIEPGIRAEVWPFLLGVYDLNSSEE 655
           +R++ +S + W++     G+  +      + +  GG+   +R + W FLLG +  +S++E
Sbjct: 312 QRREPVSLEEWTKNIDSEGRILNVDN-MKQMIFRGGLSHALRKQAWKFLLGYFPWDSTKE 370

Query: 656 ERNIIKTKKRNEYEKL 703
           ER  ++ +K +EY ++
Sbjct: 371 ERTQLQKQKTDEYFRM 386

---

>Q6BU76:GYP7_DEBHA GTPase-activating protein GYP7 - Debaryomyces hansenii (Yeast)|
            (Torulaspora hansenii)
          Length = 757

 Score =  108 bits (270), Expect = 1e-22
 Identities = 56/207 (27%), Positives = 105/207 (50%)
 Frame = +2

Query: 1280 HAARLVALLEAYALYDPEIGYCQGMSDLLSPIIAVMKEDHEAFWCFVGFMKKARHNFRLD 1459
            H  ++  +L  Y  ++  +GY QGM+DLLSP+    +++   FW FV FM +   NF  D
Sbjct: 516  HLFKMREILLTYNEHNVNLGYVQGMTDLLSPLYVTFQDESLTFWAFVNFMDRMERNFLRD 575

Query: 1460 EVGIRRQLKTVSQIIKRKDSHLYRHLQKLQAKDCFFVYRMVLVLFRRELTFEQTLCLWEV 1639
            + G++ Q+ T++++++     L++HL+K ++ D +F +RM+LV F+RE  +   L LWE+
Sbjct: 576  QSGMKNQMLTLNELVQFMLPDLFKHLEKCESTDLYFFFRMLLVWFKREFEWSSVLSLWEI 635

Query: 1640 MWADQAAVRAGIGRSTWGRIRLHAPPTDDLLLYAIAACVLQRRKLIIERYSSMDEILREC 1819
            +W D                      +    L+   A +    ++I +  S  DE+L+  
Sbjct: 636  LWTDYY--------------------SGQFHLFFALAVLSDNERIIRQNLSRFDEVLKYM 675

Query: 1820 HSMAGQLDVWRLLDDAHDLVVNLHNKI 1900
            + ++  +++  LL  A  L +     I
Sbjct: 676  NDLSMNMNLNHLLIRAELLFLRFRRMI 702



 Score = 53.5 bits (127), Expect = 4e-06
 Identities = 27/82 (32%), Positives = 43/82 (52%)
 Frame = +2

Query: 467 SRRKRKQALSCQNWSRLFSVNGKFRDGGRKFLKKVRSGGIEPGIRAEVWPFLLGVYDLNS 646
           S+  R++ +S   W  LF  +G+      +   ++  GG+E  IR E W FLL VY  +S
Sbjct: 357 SKTSRRKPISKVEWEGLFDFSGRLIISIDEIKDRIFHGGLEDCIRGEAWLFLLNVYPWDS 416

Query: 647 SEEERNIIKTKKRNEYEKLSRK 712
           S EER  ++   +  YE++  K
Sbjct: 417 SAEERKTLRNSFQTAYEEIKLK 438

---

>Q9CXF4:TBC15_MOUSE TBC1 domain family member 15 - Mus musculus (Mouse)|
          Length = 671

 Score =  106 bits (264), Expect = 5e-22
 Identities = 57/196 (29%), Positives = 102/196 (52%)
 Frame = +2

Query: 1301 LLEAYALYDPEIGYCQGMSDLLSPIIAVMKEDHEAFWCFVGFMKKARHNFRLDEVGIRRQ 1480
            +L  Y +YD ++GY QGMSDLLSP++ VM+ + +AFWCF  +M +   NF     G++ Q
Sbjct: 422  ILMTYCMYDFDLGYVQGMSDLLSPLLYVMENEVDAFWCFASYMDQMHQNFEEQMQGMKTQ 481

Query: 1481 LKTVSQIIKRKDSHLYRHLQKLQAKDCFFVYRMVLVLFRRELTFEQTLCLWEVMWADQAA 1660
            L  +S +++  DS    +L+   +   +F +R +L+ F+RE +F   L LWEVMW +   
Sbjct: 482  LIQLSTLLRLLDSGFCSYLESQDSGYLYFCFRWLLIRFKREFSFLDILRLWEVMWTEL-- 539

Query: 1661 VRAGIGRSTWGRIRLHAPPTDDLLLYAIAACVLQRRKLIIERYSSMDEILRECHSMAGQL 1840
                              P  +  L    A +   ++ I+ ++   +EIL+  + ++ ++
Sbjct: 540  ------------------PCKNFHLLLCCAILESEKQQIMAKHYGFNEILKHINELSMKI 581

Query: 1841 DVWRLLDDAHDLVVNL 1888
            DV  +L  A  + + +
Sbjct: 582  DVEDILCKAEAISLQM 597



 Score = 47.0 bits (110), Expect = 3e-04
 Identities = 21/88 (23%), Positives = 47/88 (53%)
 Frame = +2

Query: 476 KRKQALSCQNWSRLFSVNGKFRDGGRKFLKKVRSGGIEPGIRAEVWPFLLGVYDLNSSEE 655
           +R++ +S + W++     G+         +K+  GG+   +R + W FLLG +  +S++E
Sbjct: 295 QRREPVSLEEWNKSLDPEGRLV-AVESMKQKIFRGGLSHSLRKQAWKFLLGYFPWDSTKE 353

Query: 656 ERNIIKTKKRNEYEKLSRKCHQILNCQK 739
           ER  ++ +K +EY ++  +   +   Q+
Sbjct: 354 ERTQLQKQKTDEYFRMKLQWKSVSEAQE 381

---

>Q3MII6:TBC25_HUMAN TBC1 domain family member 25 - Homo sapiens (Human)|
          Length = 688

 Score =  102 bits (253), Expect = 9e-21
 Identities = 60/173 (34%), Positives = 87/173 (50%), Gaps = 8/173 (4%)
 Frame = +2

Query: 1154 RANTDWALFSCNQAEISEEKALERALSVGLKDC---DHLEPYMIY-----HAARLVALLE 1309
            R + ++       A+ +  + LE   S  LKD    D   PY        H   L  LL 
Sbjct: 260  RKSREYEQLKSEWAQRANPEDLEFIRSTVLKDVLRTDRAHPYYAGPEDGPHLRALHDLLT 319

Query: 1310 AYALYDPEIGYCQGMSDLLSPIIAVMKEDHEAFWCFVGFMKKARHNFRLDEVGIRRQLKT 1489
             YA+  P++ YCQGMSDL SPI+AVM  +  AF CF G MK+   NF  D   +  +   
Sbjct: 320  TYAVTHPQVSYCQGMSDLASPILAVMDHEGHAFVCFCGIMKRLAANFHPDGRAMATKFAH 379

Query: 1490 VSQIIKRKDSHLYRHLQKLQAKDCFFVYRMVLVLFRRELTFEQTLCLWEVMWA 1648
            +  +++  D   Y++LQ+  A D FF YR +L+  +RE  F+  L + EV W+
Sbjct: 380  LKLLLRHADPDFYQYLQEAGADDLFFCYRWLLLELKREFAFDDALRMLEVTWS 432



 Score = 40.4 bits (93), Expect = 0.033
 Identities = 20/55 (36%), Positives = 29/55 (52%)
 Frame = +2

Query: 566 KVRSGGIEPGIRAEVWPFLLGVYDLNSSEEERNIIKTKKRNEYEKLSRKCHQILN 730
           ++  GG+EP +R  VW +LL VY    +  ER     +K  EYE+L  +  Q  N
Sbjct: 223 RIYHGGVEPSLRKVVWRYLLNVYPDGLTGRERMDYMKRKSREYEQLKSEWAQRAN 277

---

>A1A5B6:TBC25_MOUSE TBC1 domain family member 25 - Mus musculus (Mouse)|
          Length = 742

 Score =  100 bits (250), Expect = 2e-20
 Identities = 60/173 (34%), Positives = 86/173 (49%), Gaps = 8/173 (4%)
 Frame = +2

Query: 1154 RANTDWALFSCNQAEISEEKALERALSVGLKDC---DHLEPYMIY-----HAARLVALLE 1309
            R + ++       A+    + LE   S  LKD    D   PY        H   L  LL 
Sbjct: 314  RKSREYEQLKSEWAQRVNPEDLEFIRSTVLKDVLRTDRAHPYYAGPEDGPHLRALHDLLT 373

Query: 1310 AYALYDPEIGYCQGMSDLLSPIIAVMKEDHEAFWCFVGFMKKARHNFRLDEVGIRRQLKT 1489
             YA+  P++ YCQGMSDL SPI+AVM  +  AF CF G MK+   NF  D   +  +   
Sbjct: 374  TYAVTHPQVSYCQGMSDLASPILAVMDHEGHAFVCFCGIMKRLAANFHPDGRAMATKFAH 433

Query: 1490 VSQIIKRKDSHLYRHLQKLQAKDCFFVYRMVLVLFRRELTFEQTLCLWEVMWA 1648
            +  +++  D   Y++LQ+  A D FF YR +L+  +RE  F+  L + EV W+
Sbjct: 434  LKLLLRHADPDFYQYLQEAGADDLFFCYRWLLLELKREFAFDDALRMLEVTWS 486



 Score = 41.2 bits (95), Expect = 0.019
 Identities = 20/55 (36%), Positives = 30/55 (54%)
 Frame = +2

Query: 566 KVRSGGIEPGIRAEVWPFLLGVYDLNSSEEERNIIKTKKRNEYEKLSRKCHQILN 730
           ++  GG+EP +R  VW +LL VY    +  ER     +K  EYE+L  +  Q +N
Sbjct: 277 RIYHGGVEPSLRKVVWRYLLNVYPDGLTGRERMDYMKRKSREYEQLKSEWAQRVN 331

---

>Q8BYH7:TBC17_MOUSE TBC1 domain family member 17 - Mus musculus (Mouse)|
          Length = 645

 Score = 97.4 bits (241), Expect = 2e-19
 Identities = 61/192 (31%), Positives = 96/192 (50%)
 Frame = +2

Query: 1301 LLEAYALYDPEIGYCQGMSDLLSPIIAVMKEDHEAFWCFVGFMKKARHNFRLDEVGIRRQ 1480
            +L  Y +Y  ++GY QGMSDLLSPI+ V++ + +AFWCF GFM+    NF   +  ++RQ
Sbjct: 403  ILLTYCMYHFDLGYVQGMSDLLSPILFVVQNEVDAFWCFCGFMELVHGNFEESQETMKRQ 462

Query: 1481 LKTVSQIIKRKDSHLYRHLQKLQAKDCFFVYRMVLVLFRRELTFEQTLCLWEVMWADQAA 1660
            L  +  +++  D  L   L    +    F +R +L+ F+RE  F   L LWEV+W     
Sbjct: 463  LGQLLLLLRVLDQPLCDFLDSQDSGSLCFCFRWLLIWFKREFPFPDVLRLWEVLWTG--- 519

Query: 1661 VRAGIGRSTWGRIRLHAPPTDDLLLYAIAACVLQRRKLIIERYSSMDEILRECHSMAGQL 1840
                             P  +  LL A A   ++R  L++  + S +EIL+  + +  +L
Sbjct: 520  ----------------LPGPNLHLLVACAILDMERDTLMLSGFGS-NEILKHINELTMKL 562

Query: 1841 DVWRLLDDAHDL 1876
             V  +L  A  L
Sbjct: 563  SVEDVLTRAEAL 574



 Score = 47.4 bits (111), Expect = 3e-04
 Identities = 24/76 (31%), Positives = 40/76 (52%)
 Frame = +2

Query: 476 KRKQALSCQNWSRLFSVNGKFRDGGRKFLKKVRSGGIEPGIRAEVWPFLLGVYDLNSSEE 655
           +R   ++ + W+R     G+ ++   +   ++ SGG+ PG+R E W FLLG     SS E
Sbjct: 276 ERAPPVTEEEWNRYVGPEGRLQNVP-ELKNRIFSGGLSPGLRREAWKFLLGYLSWESSAE 334

Query: 656 ERNIIKTKKRNEYEKL 703
           E      KK +EY ++
Sbjct: 335 EHKAHVRKKTDEYFRM 350

---

>Q9HA65:TBC17_HUMAN TBC1 domain family member 17 - Homo sapiens (Human)|
          Length = 648

 Score = 97.1 bits (240), Expect = 3e-19
 Identities = 61/192 (31%), Positives = 97/192 (50%)
 Frame = +2

Query: 1301 LLEAYALYDPEIGYCQGMSDLLSPIIAVMKEDHEAFWCFVGFMKKARHNFRLDEVGIRRQ 1480
            +L  Y +Y  ++GY QGMSDLLSPI+ V++ + +AFWCF GFM+  + NF   +  ++RQ
Sbjct: 403  ILLTYCMYHFDLGYVQGMSDLLSPILYVIQNEVDAFWCFCGFMELVQGNFEESQETMKRQ 462

Query: 1481 LKTVSQIIKRKDSHLYRHLQKLQAKDCFFVYRMVLVLFRRELTFEQTLCLWEVMWADQAA 1660
            L  +  +++  D  L   L    +    F +R +L+ F+RE  F   L LWEV+W     
Sbjct: 463  LGRLLLLLRVLDPLLCDFLDSQDSGSLCFCFRWLLIWFKREFPFPDVLRLWEVLWTG--- 519

Query: 1661 VRAGIGRSTWGRIRLHAPPTDDLLLYAIAACVLQRRKLIIERYSSMDEILRECHSMAGQL 1840
                             P  +  LL A A   ++R  L++  + S +EIL+  + +  +L
Sbjct: 520  ----------------LPGPNLHLLVACAILDMERDTLMLSGFGS-NEILKHINELTMKL 562

Query: 1841 DVWRLLDDAHDL 1876
             V  +L  A  L
Sbjct: 563  SVEDVLTRAEAL 574



 Score = 40.4 bits (93), Expect = 0.033
 Identities = 20/68 (29%), Positives = 33/68 (48%)
 Frame = +2

Query: 500 QNWSRLFSVNGKFRDGGRKFLKKVRSGGIEPGIRAEVWPFLLGVYDLNSSEEERNIIKTK 679
           + W+R     G+ +    +   ++ SGG+ P +R E W FLLG      + EE      K
Sbjct: 284 EEWARHVGPEGRLQQVP-ELKNRIFSGGLSPSLRREAWKFLLGYLSWEGTAEEHKAHIRK 342

Query: 680 KRNEYEKL 703
           K +EY ++
Sbjct: 343 KTDEYFRM 350

---

>Q8TBP0:TBC16_HUMAN TBC1 domain family member 16 - Homo sapiens (Human)|
          Length = 767

 Score = 83.6 bits (205), Expect = 3e-15
 Identities = 40/118 (33%), Positives = 67/118 (56%), Gaps = 2/118 (1%)
 Frame = +2

Query: 1301 LLEAYALYDPEIGYCQGMSDLLSPIIAVMKEDHEAFWCFVGFMKKARHNFRLDEVGIRRQ 1480
            +L  YA+Y+P +GY QGMSDL++PI+A + ++ + FWCFVG M+         +  + +Q
Sbjct: 516  ILLNYAVYNPAVGYSQGMSDLVAPILAEVLDESDTFWCFVGLMQNTIFVSSPRDEDMEKQ 575

Query: 1481 LKTVSQIIKRKDSHLYRHLQKL--QAKDCFFVYRMVLVLFRRELTFEQTLCLWEVMWA 1648
            L  + ++++      Y+HL  L        F +R +L+ F+RE    + L +WE  WA
Sbjct: 576  LLYLRELLRLTHVRFYQHLVSLGEDGLQMLFCHRWLLLCFKREFPEAEALRIWEACWA 633



 Score = 53.1 bits (126), Expect = 5e-06
 Identities = 24/53 (45%), Positives = 33/53 (62%)
 Frame = +2

Query: 554 KFLKKVRSGGIEPGIRAEVWPFLLGVYDLNSSEEERNIIKTKKRNEYEKLSRK 712
           K  K +  GGI+  IR EVWPFLL  Y   S+ EER  ++ +KR EY ++ +K
Sbjct: 416 KLRKAIFFGGIDVSIRGEVWPFLLRYYSHESTSEEREALRLQKRKEYSEIQQK 468

---

>Q8BPQ7:RUTB2_MOUSE RUN and TBC1 domain-containing protein 2 - Mus musculus (Mouse)|
          Length = 1093

 Score = 75.1 bits (183), Expect = 1e-12
 Identities = 59/214 (27%), Positives = 95/214 (44%), Gaps = 4/214 (1%)
 Frame = +2

Query: 1250 CDHLEPYMIYHAARLVALLE---AYALYDPEIGYCQGMSDLLSPIIAVMKEDHEAFWCFV 1420
            CD    Y  + AA L  L     +Y     EIGY QGM DLL+P++ ++ ++  AF CF 
Sbjct: 891  CDR--SYWYFTAANLEKLRNIMCSYIWQHIEIGYVQGMCDLLAPLLVILDDEALAFSCFT 948

Query: 1421 GFMKKARHNFRLDEVGIRRQLKTVSQIIKRKDSHLYRHL-QKLQAKDCFFVYRMVLVLFR 1597
              MK+   NF      +      +  +I+  DS L+  + Q       +F YR  L+ F+
Sbjct: 949  ELMKRMNQNFP-HGGAMDTHFANMRSLIQILDSELFELMHQNGDYTHFYFCYRWFLLDFK 1007

Query: 1598 RELTFEQTLCLWEVMWADQAAVRAGIGRSTWGRIRLHAPPTDDLLLYAIAACVLQRRKLI 1777
            REL ++    +WE +WA +    A                    +L+   A V   R +I
Sbjct: 1008 RELVYDDVFSVWETIWAAKHVSSA------------------HYVLFIALALVEVYRDII 1049

Query: 1778 IERYSSMDEILRECHSMAGQLDVWRLLDDAHDLV 1879
            +E      +I++  + MA + +  ++L  A DLV
Sbjct: 1050 LENNMDFTDIIKFFNEMAERHNAKQILQLARDLV 1083



 Score = 42.0 bits (97), Expect = 0.011
 Identities = 20/59 (33%), Positives = 32/59 (54%)
 Frame = +2

Query: 485 QALSCQNWSRLFSVNGKFRDGGRKFLKKVRSGGIEPGIRAEVWPFLLGVYDLNSSEEER 661
           Q L+   W +    +  + +  ++ L+ +  GG++P IR  VWPFLLG Y    +E ER
Sbjct: 532 QGLTASIWEKYIQDSTTYPE--QELLRLIYYGGVQPEIRRAVWPFLLGHYQFGMTEMER 588

---

>Q2NKQ1:RUTB2_HUMAN RUN and TBC1 domain-containing protein 2 - Homo sapiens (Human)|
          Length = 1148

 Score = 73.9 bits (180), Expect = 3e-12
 Identities = 54/205 (26%), Positives = 93/205 (45%), Gaps = 1/205 (0%)
 Frame = +2

Query: 1289 RLVALLEAYALYDPEIGYCQGMSDLLSPIIAVMKEDHEAFWCFVGFMKKARHNFRLDEVG 1468
            +L  ++ +Y     EIGY QGM DLL+P++ ++ ++  AF CF   MK+   NF      
Sbjct: 960  KLRNIMCSYIWQHIEIGYVQGMCDLLAPLLVILDDEALAFSCFTELMKRMNQNFP-HGGA 1018

Query: 1469 IRRQLKTVSQIIKRKDSHLYRHL-QKLQAKDCFFVYRMVLVLFRRELTFEQTLCLWEVMW 1645
            +      +  +I+  DS L+  + Q       +F YR  L+ F+REL ++    +WE +W
Sbjct: 1019 MDTHFANMRSLIQILDSELFELMHQNGDYTHFYFCYRWFLLDFKRELVYDDVFLVWETIW 1078

Query: 1646 ADQAAVRAGIGRSTWGRIRLHAPPTDDLLLYAIAACVLQRRKLIIERYSSMDEILRECHS 1825
            A +    A                    +L+   A V   R +I+E      +I++  + 
Sbjct: 1079 AAKHVSSA------------------HYVLFIALALVEVYRDIILENNMDFTDIIKFFNE 1120

Query: 1826 MAGQLDVWRLLDDAHDLVVNLHNKI 1900
            MA + +  ++L  A DLV  +   I
Sbjct: 1121 MAERHNTKQVLKLARDLVYKVQTLI 1145



 Score = 43.5 bits (101), Expect = 0.004
 Identities = 21/59 (35%), Positives = 33/59 (55%)
 Frame = +2

Query: 485 QALSCQNWSRLFSVNGKFRDGGRKFLKKVRSGGIEPGIRAEVWPFLLGVYDLNSSEEER 661
           Q L+ + W +    +  + +  ++ L+ +  GGI+P IR  VWPFLLG Y    +E ER
Sbjct: 587 QGLTARIWEQYLHDSTSYEE--QELLRLIYYGGIQPEIRKAVWPFLLGHYQFGMTETER 643

---

>Q80U12:RUTB1_MOUSE RUN and TBC1 domain-containing protein 1 - Mus musculus (Mouse)|
          Length = 1005

 Score = 72.8 bits (177), Expect = 6e-12
 Identities = 52/198 (26%), Positives = 90/198 (45%), Gaps = 1/198 (0%)
 Frame = +2

Query: 1289 RLVALLEAYALYDPEIGYCQGMSDLLSPIIAVMKEDHEAFWCFVGFMKKARHNFRLDEVG 1468
            RL  ++ +Y     ++GY QGM DLL+P++ ++  D  A+ CF   MK+   NF      
Sbjct: 817  RLRDIMCSYVWEHLDMGYVQGMCDLLAPLLVILDNDQLAYSCFSHLMKRMGQNFP-SGGA 875

Query: 1469 IRRQLKTVSQIIKRKDSHLYRHL-QKLQAKDCFFVYRMVLVLFRRELTFEQTLCLWEVMW 1645
            +      +  +I+  DS L+  + Q       +F YR  L+ F+REL +E    +WEV+W
Sbjct: 876  MDSHFANMRSLIQILDSELFELMHQNGDYTHFYFCYRWFLLDFKRELLYEDVFAVWEVIW 935

Query: 1646 ADQAAVRAGIGRSTWGRIRLHAPPTDDLLLYAIAACVLQRRKLIIERYSSMDEILRECHS 1825
            A +                     ++  +L+   A V   R++I +      +I++  + 
Sbjct: 936  AARRI------------------SSEHFVLFIALALVEAYREIIRDNNMDFTDIIKFFNE 977

Query: 1826 MAGQLDVWRLLDDAHDLV 1879
             A + D   +L  A DLV
Sbjct: 978  RAERHDAQEILRIARDLV 995



 Score = 46.6 bits (109), Expect = 5e-04
 Identities = 27/92 (29%), Positives = 45/92 (48%)
 Frame = +2

Query: 428 PPNSDRGEIKSPWSRRKRKQALSCQNWSRLFSVNGKFRDGGRKFLKKVRSGGIEPGIRAE 607
           PP +  G  K  WS+ ++ +    +N+  L            + L++V  GG+E  IR +
Sbjct: 531 PPGASGGLTKDVWSKYQKDE----KNYKEL------------ELLRQVYYGGVEHEIRKD 574

Query: 608 VWPFLLGVYDLNSSEEERNIIKTKKRNEYEKL 703
           VWPFLLG Y    S++E   + T     Y+++
Sbjct: 575 VWPFLLGHYKFGMSKKEMEQVDTAVAARYQQV 606

---

>O43147:RUTB1_HUMAN RUN and TBC1 domain-containing protein 1 - Homo sapiens (Human)|
          Length = 1006

 Score = 72.0 bits (175), Expect = 1e-11
 Identities = 52/198 (26%), Positives = 89/198 (44%), Gaps = 1/198 (0%)
 Frame = +2

Query: 1289 RLVALLEAYALYDPEIGYCQGMSDLLSPIIAVMKEDHEAFWCFVGFMKKARHNFRLDEVG 1468
            RL  ++ +Y     ++GY QGM DLL+P++  +  D  A+ CF   MK+   NF  +   
Sbjct: 818  RLRDVMCSYVWEHLDVGYVQGMCDLLAPLLVTLDNDQLAYSCFSHLMKRMSQNFP-NGGA 876

Query: 1469 IRRQLKTVSQIIKRKDSHLYRHL-QKLQAKDCFFVYRMVLVLFRRELTFEQTLCLWEVMW 1645
            +      +  +I+  DS L+  + Q       +F YR  L+ F+REL +E    +WEV+W
Sbjct: 877  MDTHFANMRSLIQILDSELFELMHQNGDYTHFYFCYRWFLLDFKRELLYEDVFAVWEVIW 936

Query: 1646 ADQAAVRAGIGRSTWGRIRLHAPPTDDLLLYAIAACVLQRRKLIIERYSSMDEILRECHS 1825
            A +                     ++  +L+   A V   R++I +      +I++  + 
Sbjct: 937  AARHI------------------SSEHFVLFIALALVEAYREIIRDNNMDFTDIIKFFNE 978

Query: 1826 MAGQLDVWRLLDDAHDLV 1879
             A   D   +L  A DLV
Sbjct: 979  RAEHHDAQEILRIARDLV 996



 Score = 44.7 bits (104), Expect = 0.002
 Identities = 27/92 (29%), Positives = 44/92 (47%)
 Frame = +2

Query: 428 PPNSDRGEIKSPWSRRKRKQALSCQNWSRLFSVNGKFRDGGRKFLKKVRSGGIEPGIRAE 607
           PP +  G  K  WS+ ++ +    +N+  L            + L++V  GGIE  IR +
Sbjct: 531 PPGASAGLTKDVWSKYQKDK----KNYKEL------------ELLRQVYYGGIEHEIRKD 574

Query: 608 VWPFLLGVYDLNSSEEERNIIKTKKRNEYEKL 703
           VWPFLLG Y    S++E   +       Y+++
Sbjct: 575 VWPFLLGHYKFGMSKKEMEQVDAVVAARYQQV 606

---

>Q8R3D1:TBC13_MOUSE TBC1 domain family member 13 - Mus musculus (Mouse)|
          Length = 400

 Score = 65.1 bits (157), Expect = 1e-09
 Identities = 42/131 (32%), Positives = 66/131 (50%), Gaps = 14/131 (10%)
 Frame = +2

Query: 1301 LLEAYALYDPEIGYCQGMSDLLSPIIAVM--------KEDHEA--FWCFVGFMKKARHNF 1450
            +L  YA  +P I Y QGM++++ P+            KE  EA  F+CF   M + R NF
Sbjct: 214  ILFIYAKLNPGIAYVQGMNEIVGPLYYTFATDPNSEWKEHAEADTFFCFTNLMAEIRDNF 273

Query: 1451 --RLDE--VGIRRQLKTVSQIIKRKDSHLYRHLQKLQAKDCFFVYRMVLVLFRRELTFEQ 1618
               LD+   GI  +++ V   +K KD  LY  LQ+   K  FF +R + +L  +E     
Sbjct: 274  IKSLDDSQCGITYKMEKVYSTLKDKDVELYLKLQEQSIKPQFFAFRWLTLLLSQEFLLPD 333

Query: 1619 TLCLWEVMWAD 1651
             + +W+ ++AD
Sbjct: 334  VIRIWDSLFAD 344

---

>Q755I4:GYP5_ASHGO GTPase-activating protein GYP5 - Ashbya gossypii (Yeast)|
            (Eremothecium gossypii)
          Length = 829

 Score = 62.4 bits (150), Expect = 8e-09
 Identities = 40/156 (25%), Positives = 75/156 (48%), Gaps = 2/156 (1%)
 Frame = +2

Query: 1190 QAEISEEKALERALSVGLKDCDHLEPYMIYHAARLVALLEAYALYDPEIGYCQGMSDLLS 1369
            Q     EKA++R       D    +   +     L  +L+AY+L+DPE+GY QGM+ + +
Sbjct: 401  QIPSEHEKAIQR-------DISRTKFIPVDKTESLFNVLKAYSLFDPEVGYTQGMAFVTA 453

Query: 1370 PIIAVMKEDHEAFWCFVGFMKK--ARHNFRLDEVGIRRQLKTVSQIIKRKDSHLYRHLQK 1543
            P++  + E+ +AF   +  MK    R  F  D  G++ +L    ++++     LY HL +
Sbjct: 454  PLLINVWEEADAFGLLIKLMKNYGLREFFLPDMPGLQLKLYEFDRLLEENSPQLYNHLIR 513

Query: 1544 LQAKDCFFVYRMVLVLFRRELTFEQTLCLWEVMWAD 1651
            L  +   +  +  L LF  +      L + +V++ +
Sbjct: 514  LGIRSSMYATQWFLTLFAYKFPLGFVLRILDVIFVE 549

---

>Q8IV04:TB10C_HUMAN Carabin - Homo sapiens (Human)|
          Length = 446

 Score = 61.6 bits (148), Expect = 1e-08
 Identities = 35/130 (26%), Positives = 64/130 (49%), Gaps = 1/130 (0%)
 Frame = +2

Query: 1292 LVALLEAYALYDPEIGYCQGMSDLLSPIIAVMKEDHEAFWCFVGFMKKARHNFRLDEV-G 1468
            L+ +L+AY LY PE GYCQ    + + ++  +  + EAFWC V   +     +    +  
Sbjct: 160  LLQVLKAYTLYRPEQGYCQAQGPVAAVLLMHLPPE-EAFWCLVQICEVYLPGYYGPHMEA 218

Query: 1469 IRRQLKTVSQIIKRKDSHLYRHLQKLQAKDCFFVYRMVLVLFRRELTFEQTLCLWEVMWA 1648
            +R   +    +++R   H+++HLQ++      ++    L LF R L F   L +W+   +
Sbjct: 219  VRLDAEVFMALLRRLLPHVHKHLQQVGVGPLLYLPEWFLCLFARSLPFPTVLRVWDAFLS 278

Query: 1649 DQAAVRAGIG 1678
            + A V   +G
Sbjct: 279  EGARVLFRVG 288

---

>Q08484:GYP1_YEAST GTPase-activating protein GYP1 - Saccharomyces cerevisiae (Baker's|
            yeast)
          Length = 637

 Score = 61.2 bits (147), Expect = 2e-08
 Identities = 35/143 (24%), Positives = 61/143 (42%), Gaps = 28/143 (19%)
 Frame = +2

Query: 1292 LVALLEAYALYDPEIGYCQGMSDLLSPIIAVMKEDH------------------------ 1399
            L  +L  +A+  P  GY QG++DL++P       ++                        
Sbjct: 360  LQRILYLWAIRHPASGYVQGINDLVTPFFETFLTEYLPPSQIDDVEIKDPSTYMVDEQIT 419

Query: 1400 ----EAFWCFVGFMKKARHNFRLDEVGIRRQLKTVSQIIKRKDSHLYRHLQKLQAKDCFF 1567
                + FWC    +++   N+   + GI RQ+K +SQ++KR D+ LY H Q    +   F
Sbjct: 420  DLEADTFWCLTKLLEQITDNYIHGQPGILRQVKNLSQLVKRIDADLYNHFQNEHVEFIQF 479

Query: 1568 VYRMVLVLFRRELTFEQTLCLWE 1636
             +R +  L  RE      + +W+
Sbjct: 480  AFRWMNCLLMREFQMGTVIRMWD 502

---

>Q8C9V1:TB10C_MOUSE Carabin - Mus musculus (Mouse)|
          Length = 444

 Score = 60.5 bits (145), Expect = 3e-08
 Identities = 34/130 (26%), Positives = 64/130 (49%), Gaps = 1/130 (0%)
 Frame = +2

Query: 1292 LVALLEAYALYDPEIGYCQGMSDLLSPIIAVMKEDHEAFWCFVGFMKKARHNFRLDEV-G 1468
            L+ +L+AY LY PE GYCQ    + + ++  +  + EAFWC V   +     +    +  
Sbjct: 158  LLQVLKAYTLYRPEQGYCQAQGPVAAVLLMHLPPE-EAFWCLVQICEVYLPGYYGPHMEA 216

Query: 1469 IRRQLKTVSQIIKRKDSHLYRHLQKLQAKDCFFVYRMVLVLFRRELTFEQTLCLWEVMWA 1648
            ++   +    +++R+   +Y+HLQ++      ++    L LF R L F   L +W+   +
Sbjct: 217  VQLDAEVFMALLRRQLPRVYKHLQQVGVGPLLYLPEWFLCLFTRSLPFPTVLRIWDAFLS 276

Query: 1649 DQAAVRAGIG 1678
            + A V   +G
Sbjct: 277  EGAKVLFRVG 286

---

>Q95LL3:TB22B_MACFA TBC1 domain family member 22B - Macaca fascicularis (Crab eating|
            macaque) (Cynomolgus monkey)
          Length = 505

 Score = 59.7 bits (143), Expect = 5e-08
 Identities = 30/135 (22%), Positives = 63/135 (46%), Gaps = 23/135 (17%)
 Frame = +2

Query: 1301 LLEAYALYDPEIGYCQGMSDLLSPIIAVMKEDH-----------------------EAFW 1411
            +L  +A+  P  GY QG++DL++P   V   ++                       ++FW
Sbjct: 294  ILFIWAIRHPASGYVQGINDLVTPFFVVFLSEYVEEDVENFDVTNLSQDMLRSIEADSFW 353

Query: 1412 CFVGFMKKARHNFRLDEVGIRRQLKTVSQIIKRKDSHLYRHLQKLQAKDCFFVYRMVLVL 1591
            C    +   + N+   + GI++++K + +++ R D  ++ H ++ + +   F +R +  L
Sbjct: 354  CMSKLLDGIQDNYTFAQPGIQKKVKALEELVSRIDEQVHNHFRRYEVEYLQFAFRWMNNL 413

Query: 1592 FRRELTFEQTLCLWE 1636
              REL    T+ LW+
Sbjct: 414  LMRELPLRCTIRLWD 428

---

>Q9NU19:TB22B_HUMAN TBC1 domain family member 22B - Homo sapiens (Human)|
          Length = 505

 Score = 59.7 bits (143), Expect = 5e-08
 Identities = 30/135 (22%), Positives = 63/135 (46%), Gaps = 23/135 (17%)
 Frame = +2

Query: 1301 LLEAYALYDPEIGYCQGMSDLLSPIIAVMKEDH-----------------------EAFW 1411
            +L  +A+  P  GY QG++DL++P   V   ++                       ++FW
Sbjct: 294  ILFIWAIRHPASGYVQGINDLVTPFFVVFLSEYVEEDVENFDVTNLSQDMLRSIEADSFW 353

Query: 1412 CFVGFMKKARHNFRLDEVGIRRQLKTVSQIIKRKDSHLYRHLQKLQAKDCFFVYRMVLVL 1591
            C    +   + N+   + GI++++K + +++ R D  ++ H ++ + +   F +R +  L
Sbjct: 354  CMSKLLDGIQDNYTFAQPGIQKKVKALEELVSRIDEQVHNHFRRYEVEYLQFAFRWMNNL 413

Query: 1592 FRRELTFEQTLCLWE 1636
              REL    T+ LW+
Sbjct: 414  LMRELPLRCTIRLWD 428

---

>Q8R5A6:TB22A_MOUSE TBC1 domain family member 22A - Mus musculus (Mouse)|
          Length = 516

 Score = 56.6 bits (135), Expect = 4e-07
 Identities = 33/136 (24%), Positives = 62/136 (45%), Gaps = 24/136 (17%)
 Frame = +2

Query: 1301 LLEAYALYDPEIGYCQGMSDLLSPIIAVM------KED------------------HEAF 1408
            +L  +A+  P  GY QG++DL++P   V       +ED                   + +
Sbjct: 304  ILFIWAIRHPASGYVQGINDLVTPFFVVFICEYTDREDVDKVDVSSVPAEVLRNIEADTY 363

Query: 1409 WCFVGFMKKARHNFRLDEVGIRRQLKTVSQIIKRKDSHLYRHLQKLQAKDCFFVYRMVLV 1588
            WC    +   + N+   + GI+ ++K + +++ R D  ++RHL   + +   F +R +  
Sbjct: 364  WCMSKLLDGIQDNYTFAQPGIQMKVKMLEELVSRIDERVHRHLDGHEVRYLQFAFRWMNN 423

Query: 1589 LFRRELTFEQTLCLWE 1636
            L  REL    T+ LW+
Sbjct: 424  LLMRELPLRCTIRLWD 439

---

>Q95KI1:TB22A_MACFA TBC1 domain family member 22A - Macaca fascicularis (Crab eating|
            macaque) (Cynomolgus monkey)
          Length = 497

 Score = 55.8 bits (133), Expect = 8e-07
 Identities = 41/194 (21%), Positives = 81/194 (41%), Gaps = 24/194 (12%)
 Frame = +2

Query: 1301 LLEAYALYDPEIGYCQGMSDLLSPIIAVMKEDH------------------------EAF 1408
            +L  +A+  P  GY QG++DL++P   V   ++                        + +
Sbjct: 285  ILFIWAIRHPASGYVQGINDLVTPFFVVFICEYIEAEEVDTVDVSGVPAEVLRNIEADTY 344

Query: 1409 WCFVGFMKKARHNFRLDEVGIRRQLKTVSQIIKRKDSHLYRHLQKLQAKDCFFVYRMVLV 1588
            WC    +   + N+   + GI+ ++K + +++ R D  ++RHL + + +   F +R +  
Sbjct: 345  WCMSKLLDGIQDNYTFAQPGIQMKVKMLEELVSRIDEQVHRHLDQHEVRYLQFAFRWMNN 404

Query: 1589 LFRRELTFEQTLCLWEVMWADQAAVRAGIGRSTWGRIRLHAPPTDDLLLYAIAACVLQRR 1768
            L  RE+    T+ LW+   ++             G    H        LY  AA +++ R
Sbjct: 405  LLMREVPLRCTIRLWDTYQSEPE-----------GFSHFH--------LYVCAAFLVRWR 445

Query: 1769 KLIIERYSSMDEIL 1810
            K I+E     + +L
Sbjct: 446  KEILEEKDFQELLL 459

---

>Q8WUA7:TB22A_HUMAN TBC1 domain family member 22A - Homo sapiens (Human)|
          Length = 517

 Score = 55.5 bits (132), Expect = 1e-06
 Identities = 30/136 (22%), Positives = 62/136 (45%), Gaps = 24/136 (17%)
 Frame = +2

Query: 1301 LLEAYALYDPEIGYCQGMSDLLSPIIAVMKEDH------------------------EAF 1408
            +L  +A+  P  GY QG++DL++P   V   ++                        + +
Sbjct: 305  ILFIWAIRHPASGYVQGINDLVTPFFVVFICEYIEAEEVDTVDVSGVPAEVLCNIEADTY 364

Query: 1409 WCFVGFMKKARHNFRLDEVGIRRQLKTVSQIIKRKDSHLYRHLQKLQAKDCFFVYRMVLV 1588
            WC    +   + N+   + GI+ ++K + +++ R D  ++RHL + + +   F +R +  
Sbjct: 365  WCMSKLLDGIQDNYTFAQPGIQMKVKMLEELVSRIDEQVHRHLDQHEVRYLQFAFRWMNN 424

Query: 1589 LFRRELTFEQTLCLWE 1636
            L  RE+    T+ LW+
Sbjct: 425  LLMREVPLRCTIRLWD 440

---

>Q80XC3:US6NL_MOUSE USP6 N-terminal-like protein - Mus musculus (Mouse)|
          Length = 819

 Score = 54.3 bits (129), Expect = 2e-06
 Identities = 34/120 (28%), Positives = 58/120 (48%), Gaps = 4/120 (3%)
 Frame = +2

Query: 1292 LVALLEAYALYDPEIGYCQGMSDLLSPIIAVMKEDHEAFWCFVGFM---KKARHNFRLDE 1462
            L  +L AY++Y+ E+GYCQGMS + + ++  M E+ +AFW  V      K A H F +  
Sbjct: 169  LFHVLAAYSIYNTEVGYCQGMSQITALLLMYMNEE-DAFWALVKLFSGPKHAMHGFFVQG 227

Query: 1463 V-GIRRQLKTVSQIIKRKDSHLYRHLQKLQAKDCFFVYRMVLVLFRRELTFEQTLCLWEV 1639
               + R  +   +I+ +  S L +HL   +    F+  +     F     F   L +W++
Sbjct: 228  FPKLLRFQEHHEKILNKFLSKLKQHLDSQEIYTSFYTMKWFFQCFLDRTPFRLNLRIWDI 287

---

>Q92738:US6NL_HUMAN USP6 N-terminal-like protein - Homo sapiens (Human)|
          Length = 828

 Score = 53.9 bits (128), Expect = 3e-06
 Identities = 34/120 (28%), Positives = 58/120 (48%), Gaps = 4/120 (3%)
 Frame = +2

Query: 1292 LVALLEAYALYDPEIGYCQGMSDLLSPIIAVMKEDHEAFWCFVGFM---KKARHNFRLDE 1462
            L  +L AY++Y+ E+GYCQGMS + + ++  M E+ +AFW  V      K A H F +  
Sbjct: 169  LFHVLAAYSIYNTEVGYCQGMSQITALLLMYMNEE-DAFWALVKLFSGPKHAMHGFFVQG 227

Query: 1463 V-GIRRQLKTVSQIIKRKDSHLYRHLQKLQAKDCFFVYRMVLVLFRRELTFEQTLCLWEV 1639
               + R  +   +I+ +  S L +HL   +    F+  +     F     F   L +W++
Sbjct: 228  FPKLLRFQEHHEKILNKFLSKLKQHLDSQEIYTSFYTMKWFFQCFLDRTPFTLNLRIWDI 287

---

>Q9BXI6:TB10A_HUMAN TBC1 domain family member 10A - Homo sapiens (Human)|
          Length = 508

 Score = 53.1 bits (126), Expect = 5e-06
 Identities = 28/130 (21%), Positives = 64/130 (49%), Gaps = 1/130 (0%)
 Frame = +2

Query: 1292 LVALLEAYALYDPEIGYCQGMSDLLSPIIAVMKEDHEAFWCFVGFMKKARHNFRLDEV-G 1468
            L  +L+AY LY PE GYCQ  + + + ++  M  + +AFWC V   +K    +  +++  
Sbjct: 179  LFRVLKAYTLYRPEEGYCQAQAPIAAVLLMHMPAE-QAFWCLVQICEKYLPGYYSEKLEA 237

Query: 1469 IRRQLKTVSQIIKRKDSHLYRHLQKLQAKDCFFVYRMVLVLFRRELTFEQTLCLWEVMWA 1648
            I+   + +  ++++     ++HL + +     ++    +  F R L +   L +W++ + 
Sbjct: 238  IQLDGEILFSLLQKVSPVAHKHLSRQKIDPLLYMTEWFMCAFSRTLPWSSVLRVWDMFFC 297

Query: 1649 DQAAVRAGIG 1678
            +   +   +G
Sbjct: 298  EGVKIIFRVG 307

---

>P58802:TB10A_MOUSE TBC1 domain family member 10A - Mus musculus (Mouse)|
          Length = 500

 Score = 52.8 bits (125), Expect = 6e-06
 Identities = 28/130 (21%), Positives = 64/130 (49%), Gaps = 1/130 (0%)
 Frame = +2

Query: 1292 LVALLEAYALYDPEIGYCQGMSDLLSPIIAVMKEDHEAFWCFVGFMKKARHNFRLDEV-G 1468
            L  +L+AY LY PE GYCQ  + + + ++  M  + +AFWC V   +K    +  +++  
Sbjct: 179  LFRVLKAYTLYRPEEGYCQAQAPIAAVLLMHMPAE-QAFWCLVQVCEKYLPGYYSEKLEA 237

Query: 1469 IRRQLKTVSQIIKRKDSHLYRHLQKLQAKDCFFVYRMVLVLFRRELTFEQTLCLWEVMWA 1648
            I+   + +  ++++     ++HL + +     ++    +  F R L +   L +W++ + 
Sbjct: 238  IQLDGEILFSLLQKVSPVAHKHLSRQKIDPLLYMTEWFMCAFARTLPWSSVLRVWDMFFC 297

Query: 1649 DQAAVRAGIG 1678
            +   +   +G
Sbjct: 298  EGVKIIFRVG 307

---

>Q12344:GYP5_YEAST GTPase-activating protein GYP5 - Saccharomyces cerevisiae (Baker's|
            yeast)
          Length = 894

 Score = 52.4 bits (124), Expect = 8e-06
 Identities = 28/122 (22%), Positives = 58/122 (47%), Gaps = 2/122 (1%)
 Frame = +2

Query: 1292 LVALLEAYALYDPEIGYCQGMSDLLSPIIAVMKEDHEAFWCFVGFMKK--ARHNFRLDEV 1465
            L  +++ Y++YDP++GY QGM  + +P++   + + E+F   VG MK    R  F     
Sbjct: 508  LYKVIKVYSVYDPDVGYTQGMGFIAAPLLINCENEAESFGLLVGLMKNYGLRELFLPGMP 567

Query: 1466 GIRRQLKTVSQIIKRKDSHLYRHLQKLQAKDCFFVYRMVLVLFRRELTFEQTLCLWEVMW 1645
            G+   L    ++++     LY  L +       +  +  L  F  +   E  L ++++++
Sbjct: 568  GLMLMLYQFDRLLEEHSPSLYNRLIREGISSTMYATQWFLTFFAYKFPLEFVLRIFDIVF 627

Query: 1646 AD 1651
             +
Sbjct: 628  VE 629

---

>O60347:TBC12_HUMAN TBC1 domain family member 12 - Homo sapiens (Human)|
          Length = 775

 Score = 50.8 bits (120), Expect = 2e-05
 Identities = 34/138 (24%), Positives = 62/138 (44%), Gaps = 4/138 (2%)
 Frame = +2

Query: 1277 YHAARLVALLEAYALYDPEIGYCQGMSDLLSPIIAVMKEDHEAFWCFVGFMKKARH--NF 1450
            YH   L ++L AY  Y P++GY QGMS  ++ ++ +  E+ +AF  F   + K      F
Sbjct: 567  YHDV-LHSILGAYTCYRPDVGYVQGMS-FIAAVLILNLEEADAFIAFANLLNKPCQLAFF 624

Query: 1451 RLDEVGIRRQLKTVSQIIKRKDSHLYRHLQKLQAKDCFFVYRMVLVLFRRELTFEQTLCL 1630
            R+D   + +   T     +   S L+ H +        ++   +  L+ + L  +    +
Sbjct: 625  RVDHSMMLKYFATFEVFFEENLSKLFLHFKSYSLTPDIYLIDWIFTLYSKSLPLDLACRV 684

Query: 1631 WEVMWAD--QAAVRAGIG 1678
            W+V   D  +   R G+G
Sbjct: 685  WDVFCRDGEEFLFRTGLG 702

---

>Q8BYJ6:TBCD4_MOUSE TBC1 domain family member 4 - Mus musculus (Mouse)|
          Length = 1307

 Score = 50.1 bits (118), Expect = 4e-05
 Identities = 31/103 (30%), Positives = 55/103 (53%), Gaps = 2/103 (1%)
 Frame = +2

Query: 1292 LVALLEAYALYDPEIGYCQGMSDLLSPIIAVMKEDHEAFWC--FVGFMKKARHNFRLDEV 1465
            L  LL+AY+L D E+GYCQG+S +   ++  M E+ +AF    F+ +    R  +R D +
Sbjct: 1000 LFNLLKAYSLLDKEVGYCQGISFVAGVLLLHMSEE-QAFEMLKFLMYDLGFRKQYRPDMM 1058

Query: 1466 GIRRQLKTVSQIIKRKDSHLYRHLQKLQAKDCFFVYRMVLVLF 1594
             ++ Q+  +S+++      LY HL++ +     +     L LF
Sbjct: 1059 SLQIQMYQLSRLLHDYHRELYNHLEENEISPSLYAAPWFLTLF 1101

---

>O60343:TBCD4_HUMAN TBC1 domain family member 4 - Homo sapiens (Human)|
          Length = 1298

 Score = 50.1 bits (118), Expect = 4e-05
 Identities = 31/108 (28%), Positives = 57/108 (52%), Gaps = 2/108 (1%)
 Frame = +2

Query: 1292 LVALLEAYALYDPEIGYCQGMSDLLSPIIAVMKEDHEAFWC--FVGFMKKARHNFRLDEV 1465
            L  LL+AY+L D E+GYCQG+S +   ++  M E+ +AF    F+ +    R  +R D +
Sbjct: 991  LFNLLKAYSLLDKEVGYCQGISFVAGVLLLHMSEE-QAFEMLKFLMYDLGFRKQYRPDMM 1049

Query: 1466 GIRRQLKTVSQIIKRKDSHLYRHLQKLQAKDCFFVYRMVLVLFRRELT 1609
             ++ Q+  +S+++      LY HL++ +     +     L LF  + +
Sbjct: 1050 SLQIQMYQLSRLLHDYHRDLYNHLEENEISPSLYAAPWFLTLFASQFS 1097

---

>Q86TI0:TBCD1_HUMAN TBC1 domain family member 1 - Homo sapiens (Human)|
          Length = 1168

 Score = 49.7 bits (117), Expect = 5e-05
 Identities = 31/103 (30%), Positives = 55/103 (53%), Gaps = 2/103 (1%)
 Frame = +2

Query: 1292 LVALLEAYALYDPEIGYCQGMSDLLSPIIAVMKEDHEAFWC--FVGFMKKARHNFRLDEV 1465
            L  +L+AY+L D E+GYCQG+S +   ++  M E+ EAF    F+ F    R  +R D +
Sbjct: 873  LYNILKAYSLLDQEVGYCQGLSFVAGILLLHMSEE-EAFKMLKFLMFDMGLRKQYRPDMI 931

Query: 1466 GIRRQLKTVSQIIKRKDSHLYRHLQKLQAKDCFFVYRMVLVLF 1594
             ++ Q+  +S+++      LY HL++ +     +     L +F
Sbjct: 932  ILQIQMYQLSRLLHDYHRDLYNHLEEHEIGPSLYAAPWFLTMF 974

---

>Q60949:TBCD1_MOUSE TBC1 domain family member 1 - Mus musculus (Mouse)|
          Length = 1255

 Score = 49.3 bits (116), Expect = 7e-05
 Identities = 31/103 (30%), Positives = 55/103 (53%), Gaps = 2/103 (1%)
 Frame = +2

Query: 1292 LVALLEAYALYDPEIGYCQGMSDLLSPIIAVMKEDHEAFWC--FVGFMKKARHNFRLDEV 1465
            L  +L+AY+L D E+GYCQG+S +   ++  M E+ EAF    F+ F    R  +R D +
Sbjct: 960  LYNILKAYSLLDQEVGYCQGLSFVAGILLLHMSEE-EAFKMLKFLMFDMGLRKQYRPDMI 1018

Query: 1466 GIRRQLKTVSQIIKRKDSHLYRHLQKLQAKDCFFVYRMVLVLF 1594
             ++ Q+  +S+++      LY HL++ +     +     L +F
Sbjct: 1019 ILQIQMYQLSRLLHDYHRDLYNHLEEHEIGPSLYAAPWFLTVF 1061

---

>O97790:TBCD1_BOVIN TBC1 domain family member 1 - Bos taurus (Bovine)|
          Length = 556

 Score = 48.9 bits (115), Expect = 9e-05
 Identities = 37/127 (29%), Positives = 64/127 (50%), Gaps = 9/127 (7%)
 Frame = +2

Query: 1241 LKDCDHLEPYMIYHAARLVA-------LLEAYALYDPEIGYCQGMSDLLSPIIAVMKEDH 1399
            L D     P   Y++A+L A       +L+AY+L D E+GYCQG+S +   ++  M E+ 
Sbjct: 237  LIDLGRTFPTHPYYSAQLGAGQLSLYNILKAYSLLDQEVGYCQGLSFVAGILLLHMGEE- 295

Query: 1400 EAF--WCFVGFMKKARHNFRLDEVGIRRQLKTVSQIIKRKDSHLYRHLQKLQAKDCFFVY 1573
            EAF    F+ F    R  +R D + ++ Q+  +S+++      LY HL++ +     +  
Sbjct: 296  EAFNMLKFLMFDMGLRKQYRPDMIILQIQMYQLSRLLHDYHRDLYNHLEEHEIGPSLYAA 355

Query: 1574 RMVLVLF 1594
               L +F
Sbjct: 356  PWFLTVF 362

---

>Q6PBU5:GRPT1_DANRE Growth hormone regulated TBC protein 1 - Danio rerio (Zebrafish)|
            (Brachydanio rerio)
          Length = 356

 Score = 48.9 bits (115), Expect = 9e-05
 Identities = 26/125 (20%), Positives = 61/125 (48%), Gaps = 1/125 (0%)
 Frame = +2

Query: 1292 LVALLEAYALYDPEIGYCQGMSDLLSPIIAVMKEDHEAFWCFVGFMKKARHNFRLDE-VG 1468
            L  +L AY  ++  +GYCQGM+ +   +I V K++  +FW     + +   ++     +G
Sbjct: 156  LYNVLVAYGHHNKAVGYCQGMNFIAGYLILVSKDEETSFWLMEALLSRILPDYYTPAMLG 215

Query: 1469 IRRQLKTVSQIIKRKDSHLYRHLQKLQAKDCFFVYRMVLVLFRRELTFEQTLCLWEVMWA 1648
            ++   + + ++++ K   +++ +Q         V R  + LF   L  E  L +W+ ++ 
Sbjct: 216  LKTDQEVLGELVRLKAPAVWKLMQDQGVMWTLVVSRWFICLFIDVLPVETVLRIWDCLFY 275

Query: 1649 DQAAV 1663
            + + +
Sbjct: 276  EGSKI 280

---

>Q9BYX2:TBCD2_HUMAN TBC1 domain family member 2 - Homo sapiens (Human)|
          Length = 917

 Score = 48.1 bits (113), Expect = 2e-04
 Identities = 32/122 (26%), Positives = 57/122 (46%), Gaps = 6/122 (4%)
 Frame = +2

Query: 1289 RLVALLEAYALYDPEIGYCQGMSDLLSPIIAVMKEDHEAFWCFVGFMKKAR------HNF 1450
            +L  +L A++  +P IGYCQG++ L +  + V++E+  AFWC V  ++         +  
Sbjct: 694  KLRRVLLAFSWQNPTIGYCQGLNRLAAIALLVLEEEESAFWCLVAIVETIMPADYYCNTL 753

Query: 1451 RLDEVGIRRQLKTVSQIIKRKDSHLYRHLQKLQAKDCFFVYRMVLVLFRRELTFEQTLCL 1630
               +V  R     +S+ + R  +HL +H   L        +   LV+F   L     L +
Sbjct: 754  TASQVDQRVLQDLLSEKLPRLMAHLGQHHVDLS----LVTFNWFLVVFADSLISNILLRV 809

Query: 1631 WE 1636
            W+
Sbjct: 810  WD 811

---

>Q6GL87:GRPT1_XENTR Growth hormone regulated TBC protein 1 - Xenopus tropicalis (Western|
            clawed frog) (Silurana tropicalis)
          Length = 342

 Score = 47.8 bits (112), Expect = 2e-04
 Identities = 28/125 (22%), Positives = 61/125 (48%), Gaps = 1/125 (0%)
 Frame = +2

Query: 1292 LVALLEAYALYDPEIGYCQGMSDLLSPIIAVMKEDHEAFWCFVGFMKKARHNFRLDEV-G 1468
            L  +L AY  ++  +GYCQGM+ +   +I V K++ +AFW     + +   ++    + G
Sbjct: 142  LYNVLVAYGQHNKTVGYCQGMNFIAGYLILVTKDEEKAFWLMDALIGQILPDYYSPAMTG 201

Query: 1469 IRRQLKTVSQIIKRKDSHLYRHLQKLQAKDCFFVYRMVLVLFRRELTFEQTLCLWEVMWA 1648
            ++   + +  ++K+K   + + ++         V R  + LF   L  E  L +W+ ++ 
Sbjct: 202  LKTDQEVLGDLVKKKIPSVAQLIETHGVMWTLLVSRWFICLFIDILPVETVLRIWDCLFF 261

Query: 1649 DQAAV 1663
            + + V
Sbjct: 262  EGSKV 266

---

>Q6GLZ0:GRTP1_XENLA Growth hormone regulated TBC protein 1 - Xenopus laevis (African|
            clawed frog)
          Length = 342

 Score = 47.4 bits (111), Expect = 3e-04
 Identities = 28/125 (22%), Positives = 61/125 (48%), Gaps = 1/125 (0%)
 Frame = +2

Query: 1292 LVALLEAYALYDPEIGYCQGMSDLLSPIIAVMKEDHEAFWCFVGFMKKARHNFRLDEV-G 1468
            L  +L AY  ++  +GYCQGM+ +   +I V K++ +AFW     + +   ++    + G
Sbjct: 142  LYNVLVAYGQHNTTVGYCQGMNFIAGYLILVTKDEEKAFWLMDALIGRILPDYYSPAMTG 201

Query: 1469 IRRQLKTVSQIIKRKDSHLYRHLQKLQAKDCFFVYRMVLVLFRRELTFEQTLCLWEVMWA 1648
            ++   + +  ++K+K   + + ++         V R  + LF   L  E  L +W+ ++ 
Sbjct: 202  LKTDQEVLGDLVKKKLPAVSQLIEAHGVMWTLLVSRWFICLFIDILPVETVLRIWDCLFF 261

Query: 1649 DQAAV 1663
            + + V
Sbjct: 262  EGSKV 266

---

>Q09445:YQ01_CAEEL Uncharacterized protein C04A2.1 - Caenorhabditis elegans|
          Length = 330

 Score = 47.0 bits (110), Expect = 3e-04
 Identities = 34/175 (19%), Positives = 72/175 (41%)
 Frame = +2

Query: 1304 LEAYALYDPEIGYCQGMSDLLSPIIAVMKEDHEAFWCFVGFMKKARHNFRLDEVGIRRQL 1483
            L A A + P +GYCQG++ +   I+ V+ ++  A    V  + + +  +  + +G+RR +
Sbjct: 140  LFAVAEHIPSVGYCQGLNFVAGVILLVVNDESRAIDLLVHLVSQRQEYYGKNMIGLRRDM 199

Query: 1484 KTVSQIIKRKDSHLYRHLQKLQAKDCFFVYRMVLVLFRRELTFEQTLCLWEVMWADQAAV 1663
              +  +++     +   L+KL       V +  +  F   L  E  L LW+ +  +    
Sbjct: 200  HVLHSLLREHCPRVVVTLEKLDVGLDMLVGKWFVCWFVESLPMETVLRLWDCLIYE---- 255

Query: 1664 RAGIGRSTWGRIRLHAPPTDDLLLYAIAACVLQRRKLIIERYSSMDEILRECHSM 1828
                                D  L+ IA  + +   + I    S+D+++ E  ++
Sbjct: 256  -------------------GDEWLFRIAVALFRSNMIAISSCESIDQLMTEVQNI 291

---

>Q9Z1A9:TBCD8_MOUSE TBC1 domain family member 8 - Mus musculus (Mouse)|
          Length = 891

 Score = 47.0 bits (110), Expect = 3e-04
 Identities = 30/90 (33%), Positives = 46/90 (51%), Gaps = 1/90 (1%)
 Frame = +2

Query: 1286 ARLVALLEAYALYDPEIGYCQGMSDLLSPIIAVMKEDHEAFWCFVGFMKKARHN-FRLDE 1462
            A L  +L AYA  +P+IGYCQ M+ L S ++   KE+ EAFW  V   ++   + F    
Sbjct: 327  AALRRVLTAYAHRNPKIGYCQSMNILTSVLLLYAKEE-EAFWLLVAVCERMLPDYFNHRV 385

Query: 1463 VGIRRQLKTVSQIIKRKDSHLYRHLQKLQA 1552
            +G +       ++IK +   L  H+  L A
Sbjct: 386  IGAQVDQSVFEELIKEQLPELAEHMSDLSA 415

---

>Q8IYX1:TBC21_HUMAN TBC1 domain family member 21 - Homo sapiens (Human)|
          Length = 336

 Score = 47.0 bits (110), Expect = 3e-04
 Identities = 25/99 (25%), Positives = 41/99 (41%)
 Frame = +2

Query: 428 PPNSDRGEIKSPWSRRKRKQALSCQNWSRLFSVNGKFRDGGRKFLKKVRSGGIEPGIRAE 607
           P NS      + +   KRK  +    W   F  +G            +   G+ P +R E
Sbjct: 6   PENSLSARQSASFILVKRKPPIDKTEWDSFFDESGHLAKSRDFICVNILERGLHPFVRTE 65

Query: 608 VWPFLLGVYDLNSSEEERNIIKTKKRNEYEKLSRKCHQI 724
            W FL G +   SS++ER  + + +R  Y+ L +   +I
Sbjct: 66  AWKFLTGYFSWQSSQDERLTVDSMRRKNYKALCQMYEKI 104



 Score = 46.2 bits (108), Expect = 6e-04
 Identities = 30/119 (25%), Positives = 57/119 (47%), Gaps = 1/119 (0%)
 Frame = +2

Query: 1289 RLVALLEAYALYDPEIGYCQGMSDLLSPIIAVMKEDHEAFWCFVGFMKKARHNFRLDEVG 1468
            RL  +L    + + +  Y QG  +++     +++ DHE FW F  F++K  H+  ++ +G
Sbjct: 144  RLEKILLLSYVCNTQAEYQQGFHEMMMLFQLMVEHDHETFWLFQFFLQKTEHSCVIN-IG 202

Query: 1469 IRRQLKTVSQIIKRKDSHLYRHLQKLQAKDCFFVYRMVLVLFRREL-TFEQTLCLWEVM 1642
            + + L  +S +I   D     HL+   A     ++      F+R   +F+    LWEV+
Sbjct: 203  VAKNLDMLSTLITFLDPVFAEHLKGKGAGAVQSLFPWFCFCFQRAFKSFDDVWRLWEVL 261

---

>Q8BM85:TBCK_MOUSE TBC domain-containing protein kinase-like protein - Mus musculus|
            (Mouse)
          Length = 762

 Score = 45.8 bits (107), Expect = 8e-04
 Identities = 37/161 (22%), Positives = 68/161 (42%), Gaps = 3/161 (1%)
 Frame = +2

Query: 1286 ARLVALLEAYALYDPEIGYCQGMSDLLSPIIAV-MKEDHEAFWCFVGFMKKARHNFRLDE 1462
            A+   +L+A+ +  P++ Y QG+  L +P + +    +  A+ C   F+ K  +NF L +
Sbjct: 526  AKFRRVLKAWVVSHPDLVYWQGLDSLCAPFLYLNFNNEALAYACMSAFIPKYLYNFFLKD 585

Query: 1463 VG--IRRQLKTVSQIIKRKDSHLYRHLQKLQAKDCFFVYRMVLVLFRRELTFEQTLCLWE 1636
                I+  L   SQ+I   D  L  HL ++      +     L +F       +   LW+
Sbjct: 586  NSHVIQEYLTVFSQMIAFHDPELSNHLNEIGFIPDLYAIPWFLTMFTHVFPLHKIFHLWD 645

Query: 1637 VMWADQAAVRAGIGRSTWGRIRLHAPPTDDLLLYAIAACVL 1759
             +    ++    IG +   ++R      D LL      C+L
Sbjct: 646  TLLLGNSSFPFCIGVAILQQLR------DRLLANGFNECIL 680

---

>Q8TEA7:TBCK_HUMAN TBC domain-containing protein kinase-like protein - Homo sapiens|
            (Human)
          Length = 893

 Score = 45.8 bits (107), Expect = 8e-04
 Identities = 37/161 (22%), Positives = 68/161 (42%), Gaps = 3/161 (1%)
 Frame = +2

Query: 1286 ARLVALLEAYALYDPEIGYCQGMSDLLSPIIAV-MKEDHEAFWCFVGFMKKARHNFRLDE 1462
            A+   +L+A+ +  P++ Y QG+  L +P + +    +  A+ C   F+ K  +NF L +
Sbjct: 526  AKFRRVLKAWVVSHPDLVYWQGLDSLCAPFLYLNFNNEALAYACMSAFIPKYLYNFFLKD 585

Query: 1463 VG--IRRQLKTVSQIIKRKDSHLYRHLQKLQAKDCFFVYRMVLVLFRRELTFEQTLCLWE 1636
                I+  L   SQ+I   D  L  HL ++      +     L +F       +   LW+
Sbjct: 586  NSHVIQEYLTVFSQMIAFHDPELSNHLNEIGFIPDLYAIPWFLTMFTHVFPLHKIFHLWD 645

Query: 1637 VMWADQAAVRAGIGRSTWGRIRLHAPPTDDLLLYAIAACVL 1759
             +    ++    IG +   ++R      D LL      C+L
Sbjct: 646  TLLLGNSSFPFCIGVAILQQLR------DRLLANGFNECIL 680

---

>Q5F361:TBCK_CHICK TBC domain-containing protein kinase-like protein - Gallus gallus|
            (Chicken)
          Length = 893

 Score = 45.8 bits (107), Expect = 8e-04
 Identities = 37/161 (22%), Positives = 68/161 (42%), Gaps = 3/161 (1%)
 Frame = +2

Query: 1286 ARLVALLEAYALYDPEIGYCQGMSDLLSPIIAV-MKEDHEAFWCFVGFMKKARHNFRLDE 1462
            A+   +L+A+ +  P++ Y QG+  L +P + +    +  A+ C   F+ K  +NF L +
Sbjct: 526  AKFRRVLKAWVVSHPDLVYWQGLDSLCAPFLYLNFNNEALAYACMSAFIPKYLYNFFLKD 585

Query: 1463 VG--IRRQLKTVSQIIKRKDSHLYRHLQKLQAKDCFFVYRMVLVLFRRELTFEQTLCLWE 1636
                I+  L   SQ+I   D  L  HL ++      +     L +F       +   LW+
Sbjct: 586  NSHVIQEYLTVFSQMIAFHDPELSNHLNEIGFIPDLYAIPWFLTMFTHVFPLHKIFHLWD 645

Query: 1637 VMWADQAAVRAGIGRSTWGRIRLHAPPTDDLLLYAIAACVL 1759
             +    ++    IG +   ++R      D LL      C+L
Sbjct: 646  TLLLGNSSFPFCIGVAILQQLR------DRLLANGFNECIL 680

---

>Q4QQU7:GRPT1_RAT Growth hormone-regulated TBC protein 1 - Rattus norvegicus (Rat)|
          Length = 289

 Score = 45.8 bits (107), Expect = 8e-04
 Identities = 26/125 (20%), Positives = 61/125 (48%), Gaps = 1/125 (0%)
 Frame = +2

Query: 1292 LVALLEAYALYDPEIGYCQGMSDLLSPIIAVMKEDHEAFWCFVGFMKKARHNFRLDE-VG 1468
            L  +L AY L++ ++GYCQGM+ +   +I + K + E+FW     + +   ++     +G
Sbjct: 90   LYNVLLAYGLHNQDVGYCQGMNFIAGYLILITKNEEESFWLLDALVGRILPDYYSPAMLG 149

Query: 1469 IRRQLKTVSQIIKRKDSHLYRHLQKLQAKDCFFVYRMVLVLFRRELTFEQTLCLWEVMWA 1648
            ++   + ++++++ K   +   +          V R  + LF   L  E  L +W+ ++ 
Sbjct: 150  LKTDQEVLAELVRMKLPAVAALMDGHGVLWTLLVSRWFICLFVDILPVETVLRIWDCLFN 209

Query: 1649 DQAAV 1663
            + + +
Sbjct: 210  EGSKI 214

---

>O95759:TBCD8_HUMAN TBC1 domain family member 8 - Homo sapiens (Human)|
          Length = 897

 Score = 45.4 bits (106), Expect = 0.001
 Identities = 30/90 (33%), Positives = 45/90 (50%), Gaps = 1/90 (1%)
 Frame = +2

Query: 1286 ARLVALLEAYALYDPEIGYCQGMSDLLSPIIAVMKEDHEAFWCFVGFMKKARHN-FRLDE 1462
            A L  +L AYA  +P+IGYCQ M+ L S ++   KE+ EAFW  V   ++   + F    
Sbjct: 328  AALRRVLTAYAHRNPKIGYCQSMNILTSVLLLYTKEE-EAFWLLVAVCERMLPDYFNHRV 386

Query: 1463 VGIRRQLKTVSQIIKRKDSHLYRHLQKLQA 1552
            +G +       ++IK     L  H+  L A
Sbjct: 387  IGAQVDQSVFEELIKGHLPELAEHMNDLSA 416

---

>Q9P2M4:TBC14_HUMAN TBC1 domain family member 14 - Homo sapiens (Human)|
          Length = 678

 Score = 43.9 bits (102), Expect = 0.003
 Identities = 40/181 (22%), Positives = 70/181 (38%), Gaps = 15/181 (8%)
 Frame = +2

Query: 1154 RANTDWALFSCNQAEISEEKA------LERALSVGLKDCDHLEPYMI-------YHAARL 1294
            RA   W   S   +E+  E A       E +L +   D     P +        YH   L
Sbjct: 417  RAKERWRSLSTGGSEVENEDAGFSAADREASLELIKLDISRTFPNLCIFQQGGPYHDM-L 475

Query: 1295 VALLEAYALYDPEIGYCQGMSDLLSPIIAVMKEDHEAFWCFVGFMKKARHN--FRLDEVG 1468
             ++L AY  Y P++GY QGMS  ++ ++ +  +  +AF  F   + K      FR+D   
Sbjct: 476  HSILGAYTCYRPDVGYVQGMS-FIAAVLILNLDTADAFIAFSNLLNKPCQMAFFRVDHGL 534

Query: 1469 IRRQLKTVSQIIKRKDSHLYRHLQKLQAKDCFFVYRMVLVLFRRELTFEQTLCLWEVMWA 1648
            +           +     L+ H +K       ++   +  L+ + L  +    +W+V   
Sbjct: 535  MLTYFAAFEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRIWDVFCR 594

Query: 1649 D 1651
            D
Sbjct: 595  D 595

---

>Q5TC63:GRTP1_HUMAN Growth hormone-regulated TBC protein 1 - Homo sapiens (Human)|
          Length = 336

 Score = 43.9 bits (102), Expect = 0.003
 Identities = 25/125 (20%), Positives = 60/125 (48%), Gaps = 1/125 (0%)
 Frame = +2

Query: 1292 LVALLEAYALYDPEIGYCQGMSDLLSPIIAVMKEDHEAFWCFVGFMKKARHNFRLDE-VG 1468
            L  +L AY  ++  +GYCQGM+ +   +I +   + E+FW     + +   ++     +G
Sbjct: 137  LYNVLLAYGHHNQGVGYCQGMNFIAGYLILITNNEEESFWLLDALVGRILPDYYSPAMLG 196

Query: 1469 IRRQLKTVSQIIKRKDSHLYRHLQKLQAKDCFFVYRMVLVLFRRELTFEQTLCLWEVMWA 1648
            ++   + + ++++ K   +   +++L       V R  + LF   L  E  L +W+ ++ 
Sbjct: 197  LKTDQEVLGELVRAKLPAVGALMERLGVLWTLLVSRWFICLFVDILPVETVLRIWDCLFN 256

Query: 1649 DQAAV 1663
            + + +
Sbjct: 257  EGSKI 261

---

>Q8CGA2:TBC14_MOUSE TBC1 domain family member 14 - Mus musculus (Mouse)|
          Length = 679

 Score = 43.5 bits (101), Expect = 0.004
 Identities = 40/181 (22%), Positives = 70/181 (38%), Gaps = 15/181 (8%)
 Frame = +2

Query: 1154 RANTDWALFSCNQAEISEEKA------LERALSVGLKDCDHLEPYMI-------YHAARL 1294
            RA   W   S   +E+  E A       E +L +   D     P +        YH   L
Sbjct: 418  RAKERWRSLSTGGSEVENEDAGFSAADREASLELIKLDISRTFPNLCIFQQGGPYHDM-L 476

Query: 1295 VALLEAYALYDPEIGYCQGMSDLLSPIIAVMKEDHEAFWCFVGFMKKARHN--FRLDEVG 1468
             ++L AY  Y P++GY QGMS  ++ ++ +  +  +AF  F   + K      FR+D   
Sbjct: 477  HSILGAYTCYRPDVGYVQGMS-FIAAVLILNLDTADAFIAFSNLLNKPCQMAFFRVDHGL 535

Query: 1469 IRRQLKTVSQIIKRKDSHLYRHLQKLQAKDCFFVYRMVLVLFRRELTFEQTLCLWEVMWA 1648
            +           +     L+ H +K       ++   +  L+ + L  +    +W+V   
Sbjct: 536  MLTYFAAFEVFFEENLPKLFAHFKKNNLTADIYLIDWIFTLYSKSLPLDLACRIWDVFCR 595

Query: 1649 D 1651
            D
Sbjct: 596  D 596

---

>Q92609:TBCD5_HUMAN TBC1 domain family member 5 - Homo sapiens (Human)|
          Length = 795

 Score = 42.7 bits (99), Expect = 0.007
 Identities = 39/173 (22%), Positives = 66/173 (38%), Gaps = 53/173 (30%)
 Frame = +2

Query: 1292 LVALLEAYALYDPEIGYCQGMSDLLSPIIAVMKEDHE----------------------- 1402
            L  +L  YA  + ++ Y QGM +LL+PI+ V+  DH+                       
Sbjct: 186  LTDVLFCYARENEQLLYKQGMHELLAPIVFVLHCDHQAFLHASESAQPSEEMKTVLNPEY 245

Query: 1403 ----AFWCFVGFMKKARHNFRLDEVGIRRQLKTV-------------------------- 1492
                A+  F   M+ A   F   E   ++  +T+                          
Sbjct: 246  LEHDAYAVFSQLMETAEPWFSTFEHDGQKGKETLMTPIPFARPQDLGPTIAIVTKVNQIQ 305

Query: 1493 SQIIKRKDSHLYRHLQKLQAKDCFFVYRMVLVLFRRELTFEQTLCLWEVMWAD 1651
              ++K+ D  LY HL +L+     +  R V +LF RE   +  L +W+ ++AD
Sbjct: 306  DHLLKKHDIELYMHLNRLEIAPQIYGLRWVRLLFGREFPLQDLLVVWDALFAD 358

---

>P48566:GYP3_YEAST GTPase-activating protein GYP3 - Saccharomyces cerevisiae (Baker's|
            yeast)
          Length = 633

 Score = 42.7 bits (99), Expect = 0.007
 Identities = 30/105 (28%), Positives = 52/105 (49%), Gaps = 10/105 (9%)
 Frame = +2

Query: 1187 NQAEISEEKALERALSVGLKDCDHLEPYM-------IYHAARLVALLEAYALYDPEIGYC 1345
            N+ ++ +   +ER L+    D  H +  +       I  + R V  L A++LY+P+IGYC
Sbjct: 266  NEKQVQDLDIIERDLNRTFPDNIHFQSSLHNKEGPPIIKSLRRV--LVAFSLYNPKIGYC 323

Query: 1346 QGMSDLLSPIIAVMKEDHEAFWCFVGFMKK---ARHNFRLDEVGI 1471
            Q M + L+ ++ +  ++  AFW  V    +     HN  L+ V I
Sbjct: 324  QSM-NFLAGLLLLFLDEERAFWMLVIITSRYLPGVHNINLEGVNI 367

---

>Q8IZP1:TBCD3_HUMAN TBC1 domain family member 3 - Homo sapiens (Human)|
          Length = 549

 Score = 42.4 bits (98), Expect = 0.009
 Identities = 18/54 (33%), Positives = 33/54 (61%)
 Frame = +2

Query: 1292 LVALLEAYALYDPEIGYCQGMSDLLSPIIAVMKEDHEAFWCFVGFMKKARHNFR 1453
            L+ +L AY  Y+PE+GYC+ +S + +  +  + E+ +AFW  V  +   RH+ +
Sbjct: 170  LLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEE-DAFWALVQLLASERHSLQ 222

---

>P35125:UBP6_HUMAN Ubiquitin carboxyl-terminal hydrolase 6 - Homo sapiens (Human)|
          Length = 1406

 Score = 42.0 bits (97), Expect = 0.011
 Identities = 18/52 (34%), Positives = 32/52 (61%)
 Frame = +2

Query: 1292 LVALLEAYALYDPEIGYCQGMSDLLSPIIAVMKEDHEAFWCFVGFMKKARHN 1447
            L  +L AY+ Y+PE+GYC+ +S + +  +  + E+ +AFW  V  +   RH+
Sbjct: 169  LFYILLAYSEYNPEVGYCRDLSHITALFLLYLPEE-DAFWALVQLLASERHS 219

---

>Q12317:MSB4_YEAST GTPase-activating protein MSB4 - Saccharomyces cerevisiae (Baker's|
            yeast)
          Length = 492

 Score = 42.0 bits (97), Expect = 0.011
 Identities = 37/112 (33%), Positives = 55/112 (49%), Gaps = 10/112 (8%)
 Frame = +2

Query: 1115 FATWQRIIRLDAIRANTDWALFSCNQAEIS--EEKALERALSVGLKDCDHL--------E 1264
            FA  QR  +LDA     D     C +  +S  + +A+ER L     D  H         E
Sbjct: 160  FAGGQR--QLDANVGVYDRLKSDCREGAVSGKDMEAIERDLYRTFPDNIHFHKESFQNGE 217

Query: 1265 PYMIYHAARLVALLEAYALYDPEIGYCQGMSDLLSPIIAVMKEDHEAFWCFV 1420
            P +I    R+   L A+++YD  IGYCQ M+ L+  ++  M+E+ +AFW  V
Sbjct: 218  PAIIRSLRRV---LMAFSVYDKTIGYCQSMNFLVGLLLLFMEEE-KAFWMLV 265

---

>Q3UYK3:TBCD9_MOUSE TBC1 domain family member 9 - Mus musculus (Mouse)|
          Length = 1264

 Score = 41.6 bits (96), Expect = 0.015
 Identities = 21/50 (42%), Positives = 30/50 (60%)
 Frame = +2

Query: 1286 ARLVALLEAYALYDPEIGYCQGMSDLLSPIIAVMKEDHEAFWCFVGFMKK 1435
            A L  +L AYA  +P IGYCQ M+ + S ++   KE+ EAFW  V   ++
Sbjct: 581  AALRRVLTAYAFRNPNIGYCQAMNIVTSVLLLYAKEE-EAFWLLVALCER 629

---

>Q6ZT07:TBCD9_HUMAN TBC1 domain family member 9 - Homo sapiens (Human)|
          Length = 1266

 Score = 41.6 bits (96), Expect = 0.015
 Identities = 21/50 (42%), Positives = 30/50 (60%)
 Frame = +2

Query: 1286 ARLVALLEAYALYDPEIGYCQGMSDLLSPIIAVMKEDHEAFWCFVGFMKK 1435
            A L  +L AYA  +P IGYCQ M+ + S ++   KE+ EAFW  V   ++
Sbjct: 581  AALRRVLTAYAFRNPNIGYCQAMNIVTSVLLLYAKEE-EAFWLLVALCER 629

---

>Q80XQ2:TBCD5_MOUSE TBC1 domain family member 5 - Mus musculus (Mouse)|
          Length = 815

 Score = 41.6 bits (96), Expect = 0.015
 Identities = 39/173 (22%), Positives = 65/173 (37%), Gaps = 53/173 (30%)
 Frame = +2

Query: 1292 LVALLEAYALYDPEIGYCQGMSDLLSPIIAVMKEDHE----------------------- 1402
            L  +L  YA  + ++ Y QGM +LL+PII  +  DH+                       
Sbjct: 186  LTDVLFCYARENEQLLYKQGMHELLAPIIFTLHCDHQAFLHASESAQPSEEMKTLLNPEY 245

Query: 1403 ----AFWCFVGFMKKARHNFRLDEVGIRRQLKTV-------------------------- 1492
                A+  F   M+ A   F   E   ++  +T+                          
Sbjct: 246  LEHDAYAMFSQLMETAEPWFSTFEHDGQKGKETLMAPIPFARPQDLGPTVAIVTKVNQIQ 305

Query: 1493 SQIIKRKDSHLYRHLQKLQAKDCFFVYRMVLVLFRRELTFEQTLCLWEVMWAD 1651
              ++K+ D  LY HL +L+     +  R V +LF RE   +  L +W+ ++AD
Sbjct: 306  DHLLKKHDIELYMHLNRLEIAPQIYGLRWVRLLFGREFPLQDLLVVWDALFAD 358

---

>O94661:GYP10_SCHPO GTPase-activating protein gyp10 - Schizosaccharomyces pombe (Fission|
            yeast)
          Length = 373

 Score = 41.6 bits (96), Expect = 0.015
 Identities = 33/131 (25%), Positives = 61/131 (46%), Gaps = 8/131 (6%)
 Frame = +2

Query: 1259 LEPYMIY-HAARLVALLEAYALYDPEIGYCQGMSDLLSPII-------AVMKEDHEAFWC 1414
            L P+++  H ++L  LL     + PE+ Y QG+ D+   ++       A+   +H  F+ 
Sbjct: 88   LNPFLLRKHRSQLTKLLSVVFKHYPELCYYQGLHDIAQILLLTLPFSHALPLMEHLVFYR 147

Query: 1415 FVGFMKKARHNFRLDEVGIRRQLKTVSQIIKRKDSHLYRHLQKLQAKDCFFVYRMVLVLF 1594
               FM        LD  G  +QL+ +  +IK +D  LY +L K   + C+F    ++  F
Sbjct: 148  LRDFMLPT-----LD--GTVKQLQLILAVIKARDPTLYEYLIKADIQ-CYFALSWLITWF 199

Query: 1595 RRELTFEQTLC 1627
              +++    +C
Sbjct: 200  AHDVSDISVVC 210

---

>P53258:GYP2_YEAST GTPase-activating protein GYP2 - Saccharomyces cerevisiae (Baker's|
            yeast)
          Length = 950

 Score = 40.8 bits (94), Expect = 0.025
 Identities = 21/66 (31%), Positives = 36/66 (54%), Gaps = 8/66 (12%)
 Frame = +2

Query: 1289 RLVALLEAYALYDPEIGYCQGMSDLLSPIIAVMKEDHEAFWCFV--------GFMKKARH 1444
            RL  +L AY+  +P++GYCQ M+ +++  +  M E+ +AFWC          G+  K  +
Sbjct: 311  RLRNVLTAYSWKNPDVGYCQAMNIVVAGFLIFMSEE-QAFWCLCNLCDIYVPGYYSKTMY 369

Query: 1445 NFRLDE 1462
               LD+
Sbjct: 370  GTLLDQ 375

---

>Q09830:YAD4_SCHPO Uncharacterized protein C4G8.04 - Schizosaccharomyces pombe (Fission|
            yeast)
          Length = 772

 Score = 40.4 bits (93), Expect = 0.033
 Identities = 22/88 (25%), Positives = 44/88 (50%), Gaps = 2/88 (2%)
 Frame = +2

Query: 1289 RLVALLEAYALYDPEIGYCQGMSDLLSPIIAVMKEDHEAFWCFVGFMKKA--RHNFRLDE 1462
            +L  +L AY+ ++P IGYCQGM+ + + ++ +   + +AF+  +  ++       F  D 
Sbjct: 570  KLRRILVAYSRHNPHIGYCQGMNVIGAFLLLLYASEEDAFYMLMSIIENVLPPKYFTPDL 629

Query: 1463 VGIRRQLKTVSQIIKRKDSHLYRHLQKL 1546
            +  R     +   +K     +Y HL+ L
Sbjct: 630  MTSRADQLVLKSFVKESLPEIYSHLELL 657

---

>Q96CN4:EVI5L_HUMAN EVI5-like protein - Homo sapiens (Human)|
          Length = 794

 Score = 40.0 bits (92), Expect = 0.043
 Identities = 20/50 (40%), Positives = 33/50 (66%)
 Frame = +2

Query: 1292 LVALLEAYALYDPEIGYCQGMSDLLSPIIAVMKEDHEAFWCFVGFMKKAR 1441
            L  +++AY+L D E+GYCQG + ++  ++  M E+ EAF  FV  M++ R
Sbjct: 179  LFNVMKAYSLVDREVGYCQGSAFIVGLLLMQMPEE-EAFCVFVRLMQEYR 227

---

>Q5SVR0:TBC9B_MOUSE TBC1 domain family member 9B - Mus musculus (Mouse)|
          Length = 1263

 Score = 39.3 bits (90), Expect = 0.073
 Identities = 18/50 (36%), Positives = 30/50 (60%)
 Frame = +2

Query: 1286 ARLVALLEAYALYDPEIGYCQGMSDLLSPIIAVMKEDHEAFWCFVGFMKK 1435
            A L  +L AYA  +P IGYCQ M ++++ ++ +   + EAFW  V   ++
Sbjct: 575  AALRRVLTAYAFRNPTIGYCQAM-NIVTSVLLLYGSEEEAFWLLVALCER 623

---

>Q66K14:TBC9B_HUMAN TBC1 domain family member 9B - Homo sapiens (Human)|
          Length = 1250

 Score = 39.3 bits (90), Expect = 0.073
 Identities = 18/50 (36%), Positives = 30/50 (60%)
 Frame = +2

Query: 1286 ARLVALLEAYALYDPEIGYCQGMSDLLSPIIAVMKEDHEAFWCFVGFMKK 1435
            A L  +L AYA  +P IGYCQ M ++++ ++ +   + EAFW  V   ++
Sbjct: 574  AALRRVLTAYAFRNPTIGYCQAM-NIVTSVLLLYGSEEEAFWLLVALCER 622

---

>O60447:EVI5_HUMAN Ecotropic viral integration site 5 protein homolog - Homo sapiens|
            (Human)
          Length = 810

 Score = 39.3 bits (90), Expect = 0.073
 Identities = 20/50 (40%), Positives = 32/50 (64%)
 Frame = +2

Query: 1292 LVALLEAYALYDPEIGYCQGMSDLLSPIIAVMKEDHEAFWCFVGFMKKAR 1441
            L  +++AY+L D E+GYCQG + ++  ++  M E+ EAF  FV  M+  R
Sbjct: 227  LFNVMKAYSLVDREVGYCQGSAFIVGLLLMQMPEE-EAFCVFVKLMQDYR 275

---

>P36618:CDC16_SCHPO Cell division control protein 16 - Schizosaccharomyces pombe (Fission|
            yeast)
          Length = 299

 Score = 38.5 bits (88), Expect = 0.12
 Identities = 29/120 (24%), Positives = 52/120 (43%), Gaps = 1/120 (0%)
 Frame = +2

Query: 1292 LVALLEAYALYDPEIGYCQGMSDLLSPIIAVMKEDHEAFWCFVGFMKKARHNFRLDEV-G 1468
            L  LL AY      + Y QGM+ L SP +   K +++AF  F   ++     + L  + G
Sbjct: 103  LSRLLNAYVWKRGAL-YVQGMNVLASPFLYACKSENQAFQFFDRLLQNECPLYVLPNIDG 161

Query: 1469 IRRQLKTVSQIIKRKDSHLYRHLQKLQAKDCFFVYRMVLVLFRRELTFEQTLCLWEVMWA 1648
            + R  K + + ++  D  LY +L         +    +L L        + L +W+ ++A
Sbjct: 162  VHRGAKLLDKCLEVLDHRLYTYLLSKGLTAKIYALPSILTLSACTAPLSEALTIWDFLFA 221

---

>Q10496:YDG9_SCHPO Uncharacterized protein C26F1.09 - Schizosaccharomyces pombe (Fission|
            yeast)
          Length = 1031

 Score = 38.1 bits (87), Expect = 0.16
 Identities = 28/122 (22%), Positives = 56/122 (45%), Gaps = 2/122 (1%)
 Frame = +2

Query: 1286 ARLVALLEAYALYDPEIGYCQGMSDLLSPIIAVMKEDHEAFWCFVGFMKK--ARHNFRLD 1459
            A L  +L + A+  P++GY QGMS +   ++  +    +AF   V   K    ++ F  +
Sbjct: 683  ANLHRVLRSLAIVLPQVGYTQGMSWIAGALLMHLPAP-QAFALLVFLFKNYHLQNIFSSE 741

Query: 1460 EVGIRRQLKTVSQIIKRKDSHLYRHLQKLQAKDCFFVYRMVLVLFRRELTFEQTLCLWEV 1639
              G+ R L   +++++     L  H ++   K C +     L LF  +   E    L+++
Sbjct: 742  MRGLSRVLHQFTRLVEDYMPSLAIHFKRQDIKTCSYASEWFLTLFAYKFPLEVVAHLYDI 801

Query: 1640 MW 1645
            ++
Sbjct: 802  LF 803

---

>Q9D3N8:GRTP1_MOUSE Growth hormone-regulated TBC protein 1 - Mus musculus (Mouse)|
          Length = 359

 Score = 38.1 bits (87), Expect = 0.16
 Identities = 27/142 (19%), Positives = 62/142 (43%), Gaps = 18/142 (12%)
 Frame = +2

Query: 1292 LVALLEAYALYDPEIGYCQ-----------------GMSDLLSPIIAVMKEDHEAFWCFV 1420
            L  +L AY L++P++GYCQ                 GM+ +   +I + K + E+FW   
Sbjct: 143  LYNVLLAYGLHNPDVGYCQCCAQKPGSSAGLRSSLTGMNFIAGYLILITKNEEESFWLLD 202

Query: 1421 GFMKKARHNFRLDE-VGIRRQLKTVSQIIKRKDSHLYRHLQKLQAKDCFFVYRMVLVLFR 1597
              + +   ++     +G++   + ++++++ K   +   +          V R  + LF 
Sbjct: 203  ALVGRILPDYYSPAMLGLKTDQEVLAELVRMKLPAVAALMDGHGVLWTLLVSRWFICLFV 262

Query: 1598 RELTFEQTLCLWEVMWADQAAV 1663
              L  E  L +W+ ++ + + +
Sbjct: 263  DILPVETVLRIWDCLFNEGSKI 284

---

>Q94F62:BAK1_ARATH BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1|
           precursor - Arabidopsis thaliana (Mouse-ear cress)
          Length = 615

 Score = 36.6 bits (83), Expect = 0.47
 Identities = 21/56 (37%), Positives = 30/56 (53%), Gaps = 1/56 (1%)
 Frame = +1

Query: 7   QITNRPRSDPHPPLSPTSPS-ARSASLSGGVDGEARRPHAGAVRVGLAPVVTIGWW 171
           ++T  P S P PP+SPT PS A S  ++G + G      AGA  +   P + + WW
Sbjct: 198 KLTPLPASPP-PPISPTPPSPAGSNRITGAIAGGVA---AGAALLFAVPAIALAWW 249

---

>Q04322:YM52_YEAST Uncharacterized protein YMR192W - Saccharomyces cerevisiae (Baker's|
            yeast)
          Length = 720

 Score = 34.7 bits (78), Expect = 1.8
 Identities = 24/116 (20%), Positives = 56/116 (48%), Gaps = 4/116 (3%)
 Frame = +2

Query: 1280 HAARLVALLEAYALYDPEIGYCQGMSDLLSPIIAVMKEDHEAFWCFVGFMKKARHNFRLD 1459
            +  R+  +L+AY L+DPE  +   ++ +++ I+ V +E+  AF   V  MK   +  RL 
Sbjct: 351  YVKRISNVLKAYLLFDPECEFSTDIAYIINMILDVCEEEANAFGLLVRLMKV--YGLRLL 408

Query: 1460 EVGIRRQLKTV----SQIIKRKDSHLYRHLQKLQAKDCFFVYRMVLVLFRRELTFE 1615
             +    ++  +     ++++     ++ H+ +   +   F+      LF+++L  E
Sbjct: 409  FLPSASEIDILCYKFDRLVEEFYPEIHNHMVEKGVRSSMFLPGFFTTLFQKKLPTE 464

---

>O18784:TRPC1_BOVIN Short transient receptor potential channel 1 - Bos taurus (Bovine)|
          Length = 793

 Score = 33.9 bits (76), Expect = 3.1
 Identities = 17/59 (28%), Positives = 37/59 (62%), Gaps = 6/59 (10%)
 Frame = +2

Query: 620 LLGVYDLNSSEEERNIIKTKKRNEYEKLSRKCHQ-----ILNCQKGFGLKVI-NETNNE 778
           +LG ++L++  +E ++++ + RN+YE+L+R+C       +   +    L+VI N T+N+
Sbjct: 234 ILGAFELSADLKELSLVEVEFRNDYEELARQCKMFAKDLLAQARNSRELEVILNHTSND 292

---

>P98166:VLDLR_RAT Very low-density lipoprotein receptor precursor - Rattus norvegicus|
           (Rat)
          Length = 873

 Score = 32.3 bits (72), Expect = 8.9
 Identities = 15/43 (34%), Positives = 24/43 (55%)
 Frame = +2

Query: 821 SVSVSAKEFSCSGSEANSPGNAACGAEECMDDDTNELTCVGPS 949
           +++ SA EF+CS     S  N  C  ++  DD ++EL C  P+
Sbjct: 151 NITCSADEFTCSSGRCVS-RNFVCNGQDDCDDGSDELDCAPPT 192

---

>P98156:VLDLR_MOUSE Very low-density lipoprotein receptor precursor - Mus musculus|
           (Mouse)
          Length = 873

 Score = 32.3 bits (72), Expect = 8.9
 Identities = 15/43 (34%), Positives = 24/43 (55%)
 Frame = +2

Query: 821 SVSVSAKEFSCSGSEANSPGNAACGAEECMDDDTNELTCVGPS 949
           +++ SA EF+CS     S  N  C  ++  DD ++EL C  P+
Sbjct: 151 NITCSADEFTCSSGRCVS-RNFVCNGQDDCDDGSDELDCAPPT 192


  Database: uniprot_sprot.fasta.out
    Posted date:  Jul 19, 2007  5:58 PM
  Number of letters in database: 100,686,439
  Number of sequences in database:  274,295
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 274295
Number of Hits to DB: 376,468,606
Number of extensions: 8030577
Number of successful extensions: 22575
Number of sequences better than 10.0: 74
Number of HSP's gapped: 22530
Number of HSP's successfully gapped: 93
Length of query: 766
Length of database: 100,686,439
Length adjustment: 121
Effective length of query: 645
Effective length of database: 67,496,744
Effective search space: 43535399880
Effective search space used: 43535399880
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

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