Clone Name	FLbaf64o03
Clone Library Name	barley_pub

---

No.	Definition	Score (bits)	E Value
1	Q9CXF4:TBC15_MOUSE TBC1 domain family member 15 - Mus musculus (...	133	3e-30
2	Q8BYH7:TBC17_MOUSE TBC1 domain family member 17 - Mus musculus (...	127	2e-28
3	Q9HA65:TBC17_HUMAN TBC1 domain family member 17 - Homo sapiens (...	127	2e-28
4	Q8TC07:TBC15_HUMAN TBC1 domain family member 15 - Homo sapiens (...	122	4e-27
5	P09379:GYP7_YARLI GTPase-activating protein GYP7 - Yarrowia lipo...	115	6e-25
6	Q6FWI1:GYP7_CANGA GTPase-activating protein GYP7 - Candida glabr...	110	2e-23
7	Q2NKQ1:RUTB2_HUMAN RUN and TBC1 domain-containing protein 2 - Ho...	109	5e-23
8	Q8BPQ7:RUTB2_MOUSE RUN and TBC1 domain-containing protein 2 - Mu...	108	6e-23
9	P48365:GYP7_YEAST GTPase-activating protein GYP7 - Saccharomyces...	103	3e-21
10	A1A5B6:TBC25_MOUSE TBC1 domain family member 25 - Mus musculus (...	102	6e-21
11	Q3MII6:TBC25_HUMAN TBC1 domain family member 25 - Homo sapiens (...	102	6e-21
12	Q80U12:RUTB1_MOUSE RUN and TBC1 domain-containing protein 1 - Mu...	101	9e-21
13	Q6BU76:GYP7_DEBHA GTPase-activating protein GYP7 - Debaryomyces ...	101	9e-21
14	O43147:RUTB1_HUMAN RUN and TBC1 domain-containing protein 1 - Ho...	101	1e-20
15	Q8TBP0:TBC16_HUMAN TBC1 domain family member 16 - Homo sapiens (...	95	1e-18
16	Q08484:GYP1_YEAST GTPase-activating protein GYP1 - Saccharomyces...	67	3e-10
17	Q80XC3:US6NL_MOUSE USP6 N-terminal-like protein - Mus musculus (...	60	4e-08
18	Q92738:US6NL_HUMAN USP6 N-terminal-like protein - Homo sapiens (...	60	4e-08
19	Q8BM85:TBCK_MOUSE TBC domain-containing protein kinase-like prot...	60	4e-08
20	Q8TEA7:TBCK_HUMAN TBC domain-containing protein kinase-like prot...	60	4e-08
21	Q5F361:TBCK_CHICK TBC domain-containing protein kinase-like prot...	60	4e-08
22	Q8R3D1:TBC13_MOUSE TBC1 domain family member 13 - Mus musculus (...	60	4e-08
23	Q95LL3:TB22B_MACFA TBC1 domain family member 22B - Macaca fascic...	59	7e-08
24	Q9NU19:TB22B_HUMAN TBC1 domain family member 22B - Homo sapiens ...	59	7e-08
25	Q755I4:GYP5_ASHGO GTPase-activating protein GYP5 - Ashbya gossyp...	59	7e-08
26	Q8WUA7:TB22A_HUMAN TBC1 domain family member 22A - Homo sapiens ...	58	1e-07
27	Q09830:YAD4_SCHPO Uncharacterized protein C4G8.04 - Schizosaccha...	57	2e-07
28	Q95KI1:TB22A_MACFA TBC1 domain family member 22A - Macaca fascic...	57	3e-07
29	Q8R5A6:TB22A_MOUSE TBC1 domain family member 22A - Mus musculus ...	56	6e-07
30	Q6GL87:GRPT1_XENTR Growth hormone regulated TBC protein 1 - Xeno...	56	6e-07
31	Q5TC63:GRTP1_HUMAN Growth hormone-regulated TBC protein 1 - Homo...	55	8e-07
32	O97790:TBCD1_BOVIN TBC1 domain family member 1 - Bos taurus (Bov...	55	1e-06
33	Q86TI0:TBCD1_HUMAN TBC1 domain family member 1 - Homo sapiens (H...	55	1e-06
34	Q8IYX1:TBC21_HUMAN TBC1 domain family member 21 - Homo sapiens (...	55	1e-06
35	Q60949:TBCD1_MOUSE TBC1 domain family member 1 - Mus musculus (M...	54	2e-06
36	Q6GLZ0:GRTP1_XENLA Growth hormone regulated TBC protein 1 - Xeno...	54	2e-06
37	Q6PBU5:GRPT1_DANRE Growth hormone regulated TBC protein 1 - Dani...	54	2e-06
38	O60447:EVI5_HUMAN Ecotropic viral integration site 5 protein hom...	54	3e-06
39	Q9BYX2:TBCD2_HUMAN TBC1 domain family member 2 - Homo sapiens (H...	53	5e-06
40	P53258:GYP2_YEAST GTPase-activating protein GYP2 - Saccharomyces...	53	5e-06
41	Q4QQU7:GRPT1_RAT Growth hormone-regulated TBC protein 1 - Rattus...	52	7e-06
42	O60343:TBCD4_HUMAN TBC1 domain family member 4 - Homo sapiens (H...	52	1e-05
43	Q8BYJ6:TBCD4_MOUSE TBC1 domain family member 4 - Mus musculus (M...	51	1e-05
44	Q96CN4:EVI5L_HUMAN EVI5-like protein - Homo sapiens (Human)	51	1e-05
45	Q12344:GYP5_YEAST GTPase-activating protein GYP5 - Saccharomyces...	51	2e-05
46	Q8IV04:TB10C_HUMAN Carabin - Homo sapiens (Human)	49	6e-05
47	Q3UYK3:TBCD9_MOUSE TBC1 domain family member 9 - Mus musculus (M...	49	9e-05
48	Q6ZT07:TBCD9_HUMAN TBC1 domain family member 9 - Homo sapiens (H...	49	9e-05
49	Q9BXI6:TB10A_HUMAN TBC1 domain family member 10A - Homo sapiens ...	48	1e-04
50	P58802:TB10A_MOUSE TBC1 domain family member 10A - Mus musculus ...	48	2e-04
51	Q5SVR0:TBC9B_MOUSE TBC1 domain family member 9B - Mus musculus (...	47	3e-04
52	Q8C9V1:TB10C_MOUSE Carabin - Mus musculus (Mouse)	46	5e-04
53	P35125:UBP6_HUMAN Ubiquitin carboxyl-terminal hydrolase 6 - Homo...	46	6e-04
54	Q66K14:TBC9B_HUMAN TBC1 domain family member 9B - Homo sapiens (...	45	0.001
55	O60347:TBC12_HUMAN TBC1 domain family member 12 - Homo sapiens (...	44	0.003
56	Q8CGA2:TBC14_MOUSE TBC1 domain family member 14 - Mus musculus (...	42	0.007
57	Q9P2M4:TBC14_HUMAN TBC1 domain family member 14 - Homo sapiens (...	42	0.007
58	Q9Z1A9:TBCD8_MOUSE TBC1 domain family member 8 - Mus musculus (M...	41	0.015
59	O95759:TBCD8_HUMAN TBC1 domain family member 8 - Homo sapiens (H...	41	0.015
60	Q09445:YQ01_CAEEL Uncharacterized protein C04A2.1 - Caenorhabdit...	41	0.020
61	Q8IZP1:TBCD3_HUMAN TBC1 domain family member 3 - Homo sapiens (H...	40	0.026
62	Q9D3N8:GRTP1_MOUSE Growth hormone-regulated TBC protein 1 - Mus ...	40	0.026
63	Q80XQ2:TBCD5_MOUSE TBC1 domain family member 5 - Mus musculus (M...	39	0.075
64	Q92609:TBCD5_HUMAN TBC1 domain family member 5 - Homo sapiens (H...	39	0.098
65	Q8IX21:CJ006_HUMAN Uncharacterized protein C10orf6 - Homo sapien...	36	0.49
66	Q2T9Q1:TBC20_BOVIN TBC1 domain family member 20 - Bos taurus (Bo...	34	1.8
67	Q5REF4:CJ006_PONPY Uncharacterized protein C10orf6 homolog - Pon...	34	2.4
68	Q96BZ9:TBC20_HUMAN TBC1 domain family member 20 - Homo sapiens (...	33	4.1
69	Q12317:MSB4_YEAST GTPase-activating protein MSB4 - Saccharomyces...	33	5.4
70	P48566:GYP3_YEAST GTPase-activating protein GYP3 - Saccharomyces...	32	7.0

---

>Q9CXF4:TBC15_MOUSE TBC1 domain family member 15 - Mus musculus (Mouse)|
          Length = 671
 Score =  133 bits (334), Expect = 3e-30
 Identities = 91/300 (30%), Positives = 143/300 (47%), Gaps = 3/300 (1%)
 Frame = +1

Query: 349  IKAGKTLSVRKWQAAFNPDGCL-DIASVLSRIQKGGVHPTVRGEVWEFLLGCFDPRSTFD 525
            ++  + +S+ +W  + +P+G L  + S+  +I +GG+  ++R + W+FLLG F   ST +
Sbjct: 294  VQRREPVSLEEWNKSLDPEGRLVAVESMKQKIFRGGLSHSLRKQAWKFLLGYFPWDSTKE 353

Query: 526  XXXXXXXXXXLQYARWKEECREMDSHVGSGKVITAPLITEDGRPIKDPLVLLEATSNQNT 705
                       +Y R K + + +                             EA   +N+
Sbjct: 354  ERTQLQKQKTDEYFRMKLQWKSVS----------------------------EAQEKRNS 385

Query: 706  SDGASTSSNNGIEVDDSAERITDKQIIEWKLTLHQIGLDVLRTDRTMVFYENKEN--LSK 879
                               R+ D + +        I  DV RTDRT  FYE ++N  L  
Sbjct: 386  -------------------RLRDYRSL--------IEKDVNRTDRTNKFYEGQDNPGLIL 418

Query: 880  LWDILAVYAWIDKDVGYCQGMSDLCSPMIVLLNDEADAFWCFEKLMRRLRGNFRCTDQSV 1059
            L DIL  Y   D D+GY QGMSDL SP++ ++ +E DAFWCF   M ++  NF   +Q  
Sbjct: 419  LHDILMTYCMYDFDLGYVQGMSDLLSPLLYVMENEVDAFWCFASYMDQMHQNFE--EQMQ 476

Query: 1060 GVANQLQHLASIIQVLDPKLHDHLETLGGGDYLFAFRMFMVLFRREVSFGDSLYLWEMMW 1239
            G+  QL  L++++++LD     +LE+   G   F FR  ++ F+RE SF D L LWE+MW
Sbjct: 477  GMKTQLIQLSTLLRLLDSGFCSYLESQDSGYLYFCFRWLLIRFKREFSFLDILRLWEVMW 536

---

>Q8BYH7:TBC17_MOUSE TBC1 domain family member 17 - Mus musculus (Mouse)|
          Length = 645

 Score =  127 bits (319), Expect = 2e-28
 Identities = 92/300 (30%), Positives = 134/300 (44%), Gaps = 3/300 (1%)
 Frame = +1

Query: 349  IKAGKTLSVRKWQAAFNPDGCL-DIASVLSRIQKGGVHPTVRGEVWEFLLGCFDPRSTFD 525
            ++    ++  +W     P+G L ++  + +RI  GG+ P +R E W+FLLG         
Sbjct: 275  VERAPPVTEEEWNRYVGPEGRLQNVPELKNRIFSGGLSPGLRREAWKFLLG--------- 325

Query: 526  XXXXXXXXXXLQYARWKEECREMDSHVGSGKVITAPLITEDGRPIKDPLVLLEATSNQNT 705
                        Y  W+    E  +HV               R   D    ++       
Sbjct: 326  ------------YLSWESSAEEHKAHV---------------RKKTDEYFRMKLQWKSV- 357

Query: 706  SDGASTSSNNGIEVDDSAERITDKQIIEWKLTLHQIGLDVLRTDRTMVFYENKEN--LSK 879
                            SAE+     ++    +L  I  DV RTDRT  FYE  EN  LS 
Sbjct: 358  ----------------SAEQERRNSLLHGYRSL--IERDVSRTDRTNKFYEGPENPGLSL 399

Query: 880  LWDILAVYAWIDKDVGYCQGMSDLCSPMIVLLNDEADAFWCFEKLMRRLRGNFRCTDQSV 1059
            L DIL  Y     D+GY QGMSDL SP++ ++ +E DAFWCF   M  + GNF  + ++ 
Sbjct: 400  LHDILLTYCMYHFDLGYVQGMSDLLSPILFVVQNEVDAFWCFCGFMELVHGNFEESQET- 458

Query: 1060 GVANQLQHLASIIQVLDPKLHDHLETLGGGDYLFAFRMFMVLFRREVSFGDSLYLWEMMW 1239
             +  QL  L  +++VLD  L D L++   G   F FR  ++ F+RE  F D L LWE++W
Sbjct: 459  -MKRQLGQLLLLLRVLDQPLCDFLDSQDSGSLCFCFRWLLIWFKREFPFPDVLRLWEVLW 517

---

>Q9HA65:TBC17_HUMAN TBC1 domain family member 17 - Homo sapiens (Human)|
          Length = 648

 Score =  127 bits (318), Expect = 2e-28
 Identities = 89/300 (29%), Positives = 132/300 (44%), Gaps = 3/300 (1%)
 Frame = +1

Query: 349  IKAGKTLSVRKWQAAFNPDGCLD-IASVLSRIQKGGVHPTVRGEVWEFLLGCFDPRSTFD 525
            ++ G  ++  +W     P+G L  +  + +RI  GG+ P++R E W+FLLG         
Sbjct: 275  VERGPPVTEEEWARHVGPEGRLQQVPELKNRIFSGGLSPSLRREAWKFLLG--------- 325

Query: 526  XXXXXXXXXXLQYARWKEECREMDSHVGSGKVITAPLITEDGRPIKDPLVLLEATSNQNT 705
                        Y  W+    E  +H+            +     +  L     +  Q  
Sbjct: 326  ------------YLSWEGTAEEHKAHIRK----------KTDEYFRMKLQWKSVSPEQER 363

Query: 706  SDGASTSSNNGIEVDDSAERITDKQIIEWKLTLHQIGLDVLRTDRTMVFYENKEN--LSK 879
             +       + IE D S                        RTDRT  FYE  EN  L  
Sbjct: 364  RNSLLHGYRSLIERDVS------------------------RTDRTNKFYEGPENPGLGL 399

Query: 880  LWDILAVYAWIDKDVGYCQGMSDLCSPMIVLLNDEADAFWCFEKLMRRLRGNFRCTDQSV 1059
            L DIL  Y     D+GY QGMSDL SP++ ++ +E DAFWCF   M  ++GNF  + ++ 
Sbjct: 400  LNDILLTYCMYHFDLGYVQGMSDLLSPILYVIQNEVDAFWCFCGFMELVQGNFEESQET- 458

Query: 1060 GVANQLQHLASIIQVLDPKLHDHLETLGGGDYLFAFRMFMVLFRREVSFGDSLYLWEMMW 1239
             +  QL  L  +++VLDP L D L++   G   F FR  ++ F+RE  F D L LWE++W
Sbjct: 459  -MKRQLGRLLLLLRVLDPLLCDFLDSQDSGSLCFCFRWLLIWFKREFPFPDVLRLWEVLW 517

---

>Q8TC07:TBC15_HUMAN TBC1 domain family member 15 - Homo sapiens (Human)|
          Length = 691

 Score =  122 bits (307), Expect = 4e-27
 Identities = 64/142 (45%), Positives = 88/142 (61%), Gaps = 2/142 (1%)
 Frame = +1

Query: 820  DVLRTDRTMVFYENKEN--LSKLWDILAVYAWIDKDVGYCQGMSDLCSPMIVLLNDEADA 993
            DV RTDRT  FYE ++N  L  L DIL  Y   D D+GY QGMSDL SP++ ++ +E DA
Sbjct: 414  DVNRTDRTNKFYEGQDNPGLILLHDILMTYCMYDFDLGYVQGMSDLLSPLLYVMENEVDA 473

Query: 994  FWCFEKLMRRLRGNFRCTDQSVGVANQLQHLASIIQVLDPKLHDHLETLGGGDYLFAFRM 1173
            FWCF   M ++  NF   +Q  G+  QL  L++++++LD     +LE+   G   F FR 
Sbjct: 474  FWCFASYMDQMHQNFE--EQMQGMKTQLIQLSTLLRLLDSGFCSYLESQDSGYLYFCFRW 531

Query: 1174 FMVLFRREVSFGDSLYLWEMMW 1239
             ++ F+RE SF D L LWE+MW
Sbjct: 532  LLIRFKREFSFLDILRLWEVMW 553

---

>P09379:GYP7_YARLI GTPase-activating protein GYP7 - Yarrowia lipolytica (Candida|
            lipolytica)
          Length = 730

 Score =  115 bits (288), Expect = 6e-25
 Identities = 99/339 (29%), Positives = 142/339 (41%), Gaps = 11/339 (3%)
 Frame = +1

Query: 367  LSVRKWQAAFNPDGCLDIA--SVLSRIQKGGVHPTVRGEVWEFLLGCFDPRSTFDXXXXX 540
            +S+ +W A F+ +G L +    V  RI  GG+ P VR E W FLLG +   ST       
Sbjct: 358  VSLAEWNAFFDYNGRLIVTVNEVKERIFHGGLAPAVRPEGWLFLLGVYPWDSTAAERKEL 417

Query: 541  XXXXXLQYAR-----WKEECREMDSHVGSGKVITAPLITEDGRPIKDPLVLLEATSNQNT 705
                 + Y R     W +E +E D                     +D L  +E       
Sbjct: 418  VSKLRVDYNRLKKEWWVQEDKERDDF------------------WRDQLSRIE------- 452

Query: 706  SDGASTSSNNGIEVDDSAERITDKQIIEWKLTLHQIGLDVLRTDRTMVFYENKEN----L 873
             D   T  N     +  A++  D                    D+    + ++ N    L
Sbjct: 453  KDVHRTDRNITFFAECDAKKDGDDD----------------NYDKDEFGFSSQINSNIHL 496

Query: 874  SKLWDILAVYAWIDKDVGYCQGMSDLCSPMIVLLNDEADAFWCFEKLMRRLRGNFRCTDQ 1053
             +L D+L  Y   +K++GY QGMSDL SP+ V+L D+  AFW F   M R+  N+   DQ
Sbjct: 497  IQLRDMLITYNQHNKNLGYVQGMSDLLSPLYVVLQDDTLAFWAFSAFMERMERNY-LRDQ 555

Query: 1054 SVGVANQLQHLASIIQVLDPKLHDHLETLGGGDYLFAFRMFMVLFRREVSFGDSLYLWEM 1233
            S G+ NQL  L  ++Q + P L+ HLE     +  F FRM +V F+RE+ + D L LWE+
Sbjct: 556  S-GMRNQLLCLDHLVQFMLPSLYKHLEKTESTNLFFFFRMLLVWFKRELLWDDVLRLWEV 614

Query: 1234 MWALEYDPDIFFAACEEASGAHKKVSKSKLRGVRHFAKW 1350
            +W            C      HK V    L G     K+
Sbjct: 615  LWTDYLSSQFVLFVCLAILDKHKDVMIDHLAGFDEILKY 653

---

>Q6FWI1:GYP7_CANGA GTPase-activating protein GYP7 - Candida glabrata (Yeast) (Torulopsis|
            glabrata)
          Length = 745

 Score =  110 bits (275), Expect = 2e-23
 Identities = 98/397 (24%), Positives = 175/397 (44%), Gaps = 11/397 (2%)
 Frame = +1

Query: 367  LSVRKWQAAFNPDGCLDIA--SVLSRIQKGGV-HPTVRGEVWEFLLGCFDPRSTFDXXXX 537
            ++ +KW + F+ +G L +    V   I  GG+     R EVW FLLG +   S+ D    
Sbjct: 360  MTKQKWNSLFDSEGRLTVTVNEVKDYIFHGGLADDATRKEVWPFLLGVYPWDSSEDERKQ 419

Query: 538  XXXXXXLQYARWKEECREMDSHVGSGKVITAPLITEDGRPIKDPLVLLEAT---SNQNTS 708
                   +Y   K++  + + ++ +          ++    KD L  +E     +++N  
Sbjct: 420  LRKALHDEYMELKQKWVDREVNLDN----------DEEEYWKDQLFRIEKDVKRNDRNID 469

Query: 709  DGASTSSNNGIEVDDSAERITDKQIIEWKLTLHQIGLDVLRTDRTMVFYENKENLSKLWD 888
                 +S+N    +D+A    D   I+                          NL KL D
Sbjct: 470  IYKYNTSDNLPFPEDTAPTTDDDDSIK------------------------NPNLKKLAD 505

Query: 889  ILAVYAWIDKDVGYCQGMSDLCSPMIVLLNDEADAFWCFEKLMRRLRGNFRCTDQSVGVA 1068
            IL  Y   + ++GY QGM+DL SP+  ++ DE   FWCF   M R+  NF   DQS G+ 
Sbjct: 506  ILTTYNIFNPNLGYVQGMTDLLSPLYYIIRDEETTFWCFTNFMERMERNF-LRDQS-GIR 563

Query: 1069 NQLQHLASIIQVLDPKLHDHLETLGGGDYLFAFRMFMVLFRREVSFGDSLYLWEM----M 1236
            +Q+  L  + Q++ P+L  HL+     D  F FRM +V F+RE ++ D   +WE+     
Sbjct: 564  DQMLALTDLCQLMLPRLSAHLQKCDSSDLFFCFRMLLVWFKREFNYDDIFNIWEVFFTDF 623

Query: 1237 WALEYDPDIFFAACEEASGAHKKVSKSKLRGVRHFAKWDKDKD-KDVPEETDGPVPISVF 1413
            ++ +Y      A  ++ S       ++  + +++F   +   + +D+   ++  + I   
Sbjct: 624  YSSQYQLFFMLAILQKNSSPIVNNLQTFDQVIKYFNDLNSKMNWRDLMVRSE-LLFIQFH 682

Query: 1414 MVASVLKEKREKLLQEARGLDDLIRILNDVNGNLDAK 1524
              A +L  ++E+L+ E  G D      +D+ G  + K
Sbjct: 683  KTADLLARRQEQLIPENSGHD-----TSDIEGGTEPK 714

---

>Q2NKQ1:RUTB2_HUMAN RUN and TBC1 domain-containing protein 2 - Homo sapiens (Human)|
          Length = 1148

 Score =  109 bits (272), Expect = 5e-23
 Identities = 63/181 (34%), Positives = 102/181 (56%), Gaps = 3/181 (1%)
 Frame = +1

Query: 718  STSSNNGIEVDDSAERITDKQIIEWKLTLHQIGLDVLRTDRTMVFYENKENLSKLWDILA 897
            +TS+N    V  S    + + +  + + LH+I  DV R DR   +Y    NL KL +I+ 
Sbjct: 908  TTSANEVSPVSSSGVTYSPELLDLYTVNLHRIEKDVQRCDRNY-WYFTPANLEKLRNIMC 966

Query: 898  VYAWIDKDVGYCQGMSDLCSPMIVLLNDEADAFWCFEKLMRRLRGNFRCTDQSVGVANQL 1077
             Y W   ++GY QGM DL +P++V+L+DEA AF CF +LM+R+  NF        +    
Sbjct: 967  SYIWQHIEIGYVQGMCDLLAPLLVILDDEALAFSCFTELMKRMNQNF---PHGGAMDTHF 1023

Query: 1078 QHLASIIQVLDPKLHDHLETLGGGDY---LFAFRMFMVLFRREVSFGDSLYLWEMMWALE 1248
             ++ S+IQ+LD +L + +     GDY    F +R F++ F+RE+ + D   +WE +WA +
Sbjct: 1024 ANMRSLIQILDSELFELMHQ--NGDYTHFYFCYRWFLLDFKRELVYDDVFLVWETIWAAK 1081

Query: 1249 Y 1251
            +
Sbjct: 1082 H 1082



 Score = 36.6 bits (83), Expect = 0.37
 Identities = 17/48 (35%), Positives = 25/48 (52%)
 Frame = +1

Query: 355 AGKTLSVRKWQAAFNPDGCLDIASVLSRIQKGGVHPTVRGEVWEFLLG 498
           AG+ L+ R W+   +     +   +L  I  GG+ P +R  VW FLLG
Sbjct: 585 AGQGLTARIWEQYLHDSTSYEEQELLRLIYYGGIQPEIRKAVWPFLLG 632

---

>Q8BPQ7:RUTB2_MOUSE RUN and TBC1 domain-containing protein 2 - Mus musculus (Mouse)|
          Length = 1093

 Score =  108 bits (271), Expect = 6e-23
 Identities = 62/181 (34%), Positives = 103/181 (56%), Gaps = 3/181 (1%)
 Frame = +1

Query: 718  STSSNNGIEVDDSAERITDKQIIEWKLTLHQIGLDVLRTDRTMVFYENKENLSKLWDILA 897
            S+++N    V  S    + + +  + + LH+I  DV R DR+  +Y    NL KL +I+ 
Sbjct: 853  SSANNEASPVSSSGVTYSPELLDLYTVNLHRIEKDVQRCDRSY-WYFTAANLEKLRNIMC 911

Query: 898  VYAWIDKDVGYCQGMSDLCSPMIVLLNDEADAFWCFEKLMRRLRGNFRCTDQSVGVANQL 1077
             Y W   ++GY QGM DL +P++V+L+DEA AF CF +LM+R+  NF        +    
Sbjct: 912  SYIWQHIEIGYVQGMCDLLAPLLVILDDEALAFSCFTELMKRMNQNF---PHGGAMDTHF 968

Query: 1078 QHLASIIQVLDPKLHDHLETLGGGDY---LFAFRMFMVLFRREVSFGDSLYLWEMMWALE 1248
             ++ S+IQ+LD +L + +     GDY    F +R F++ F+RE+ + D   +WE +WA +
Sbjct: 969  ANMRSLIQILDSELFELMHQ--NGDYTHFYFCYRWFLLDFKRELVYDDVFSVWETIWAAK 1026

Query: 1249 Y 1251
            +
Sbjct: 1027 H 1027



 Score = 33.1 bits (74), Expect = 4.1
 Identities = 17/48 (35%), Positives = 22/48 (45%)
 Frame = +1

Query: 355 AGKTLSVRKWQAAFNPDGCLDIASVLSRIQKGGVHPTVRGEVWEFLLG 498
           AG+ L+   W+             +L  I  GGV P +R  VW FLLG
Sbjct: 530 AGQGLTASIWEKYIQDSTTYPEQELLRLIYYGGVQPEIRRAVWPFLLG 577

---

>P48365:GYP7_YEAST GTPase-activating protein GYP7 - Saccharomyces cerevisiae (Baker's|
            yeast)
          Length = 746

 Score =  103 bits (256), Expect = 3e-21
 Identities = 63/234 (26%), Positives = 102/234 (43%)
 Frame = +1

Query: 868  NLSKLWDILAVYAWIDKDVGYCQGMSDLCSPMIVLLNDEADAFWCFEKLMRRLRGNFRCT 1047
            +L  L +IL  Y   + ++GY QGM+DL SP+ V++ +E   FWCF   M  +  NF   
Sbjct: 509  HLIHLQNILITYNVYNTNLGYVQGMTDLLSPIYVIMKEEWKTFWCFTHFMDIMERNF-LR 567

Query: 1048 DQSVGVANQLQHLASIIQVLDPKLHDHLETLGGGDYLFAFRMFMVLFRREVSFGDSLYLW 1227
            DQS G+  Q+  L  ++Q++ P+L +HL     G+  F FRM +V F+RE    D +++W
Sbjct: 568  DQS-GIHEQMLTLVELVQLMLPELSEHLNKCDSGNLFFCFRMLLVWFKREFEMEDIMHIW 626

Query: 1228 EMMWALEYDPDIFFAACEEASGAHKKVSKSKLRGVRHFAKWDKDKDKDVPEETDGPVPIS 1407
            E  W   Y                                                    
Sbjct: 627  ENFWTFYYSSQ-----------------------------------------------FQ 639

Query: 1408 VFMVASVLKEKREKLLQEARGLDDLIRILNDVNGNLDAKKACAGALKLHKKYLK 1569
            +F + ++L++  + +LQ     D +++  N++NG LD       A  L KK+ K
Sbjct: 640  LFFMLAILQKNSQAILQHLNQFDQILKFFNELNGKLDWNDLMVRAELLFKKFEK 693

---

>A1A5B6:TBC25_MOUSE TBC1 domain family member 25 - Mus musculus (Mouse)|
          Length = 742

 Score =  102 bits (254), Expect = 6e-21
 Identities = 56/150 (37%), Positives = 85/150 (56%), Gaps = 4/150 (2%)
 Frame = +1

Query: 820  DVLRTDRTMVFYENKEN---LSKLWDILAVYAWIDKDVGYCQGMSDLCSPMIVLLNDEAD 990
            DVLRTDR   +Y   E+   L  L D+L  YA     V YCQGMSDL SP++ +++ E  
Sbjct: 345  DVLRTDRAHPYYAGPEDGPHLRALHDLLTTYAVTHPQVSYCQGMSDLASPILAVMDHEGH 404

Query: 991  AFWCFEKLMRRLRGNFRCTDQSVGVANQLQHLASIIQVLDPKLHDHLETLGGGDYLFAFR 1170
            AF CF  +M+RL  NF    ++  +A +  HL  +++  DP  + +L+  G  D  F +R
Sbjct: 405  AFVCFCGIMKRLAANFHPDGRA--MATKFAHLKLLLRHADPDFYQYLQEAGADDLFFCYR 462

Query: 1171 MFMVLFRREVSFGDSLYLWEMMW-ALEYDP 1257
              ++  +RE +F D+L + E+ W +L  DP
Sbjct: 463  WLLLELKREFAFDDALRMLEVTWSSLPPDP 492

---

>Q3MII6:TBC25_HUMAN TBC1 domain family member 25 - Homo sapiens (Human)|
          Length = 688

 Score =  102 bits (254), Expect = 6e-21
 Identities = 56/150 (37%), Positives = 85/150 (56%), Gaps = 4/150 (2%)
 Frame = +1

Query: 820  DVLRTDRTMVFYENKEN---LSKLWDILAVYAWIDKDVGYCQGMSDLCSPMIVLLNDEAD 990
            DVLRTDR   +Y   E+   L  L D+L  YA     V YCQGMSDL SP++ +++ E  
Sbjct: 291  DVLRTDRAHPYYAGPEDGPHLRALHDLLTTYAVTHPQVSYCQGMSDLASPILAVMDHEGH 350

Query: 991  AFWCFEKLMRRLRGNFRCTDQSVGVANQLQHLASIIQVLDPKLHDHLETLGGGDYLFAFR 1170
            AF CF  +M+RL  NF    ++  +A +  HL  +++  DP  + +L+  G  D  F +R
Sbjct: 351  AFVCFCGIMKRLAANFHPDGRA--MATKFAHLKLLLRHADPDFYQYLQEAGADDLFFCYR 408

Query: 1171 MFMVLFRREVSFGDSLYLWEMMW-ALEYDP 1257
              ++  +RE +F D+L + E+ W +L  DP
Sbjct: 409  WLLLELKREFAFDDALRMLEVTWSSLPPDP 438

---

>Q80U12:RUTB1_MOUSE RUN and TBC1 domain-containing protein 1 - Mus musculus (Mouse)|
          Length = 1005

 Score =  101 bits (252), Expect = 9e-21
 Identities = 56/152 (36%), Positives = 89/152 (58%), Gaps = 3/152 (1%)
 Frame = +1

Query: 796  LTLHQIGLDVLRTDRTMVFYENKENLSKLWDILAVYAWIDKDVGYCQGMSDLCSPMIVLL 975
            L LH+I  DV R DR   +Y    NL +L DI+  Y W   D+GY QGM DL +P++V+L
Sbjct: 791  LNLHRIDKDVQRCDRNY-WYFTTSNLERLRDIMCSYVWEHLDMGYVQGMCDLLAPLLVIL 849

Query: 976  NDEADAFWCFEKLMRRLRGNFRCTDQSVGVANQLQHLASIIQVLDPKLHDHLETLGGGDY 1155
            +++  A+ CF  LM+R+  NF        + +   ++ S+IQ+LD +L + +     GDY
Sbjct: 850  DNDQLAYSCFSHLMKRMGQNF---PSGGAMDSHFANMRSLIQILDSELFELMHQ--NGDY 904

Query: 1156 ---LFAFRMFMVLFRREVSFGDSLYLWEMMWA 1242
                F +R F++ F+RE+ + D   +WE++WA
Sbjct: 905  THFYFCYRWFLLDFKRELLYEDVFAVWEVIWA 936

---

>Q6BU76:GYP7_DEBHA GTPase-activating protein GYP7 - Debaryomyces hansenii (Yeast)|
            (Torulaspora hansenii)
          Length = 757

 Score =  101 bits (252), Expect = 9e-21
 Identities = 68/209 (32%), Positives = 98/209 (46%), Gaps = 42/209 (20%)
 Frame = +1

Query: 772  DKQIIE-WKLTLHQIGLDVLRTDRTMVFYENKENLS------------------------ 876
            DK+ ++ WK   H+I  D+ RTDR +  ++NK+ +S                        
Sbjct: 444  DKRSVDFWKDQKHRIEKDINRTDRNLSIFQNKKKISISGVGSDRLPTTRESSPETPDEAD 503

Query: 877  ---------------KLWDILAVYAWIDKDVGYCQGMSDLCSPMIVLLNDEADAFWCFEK 1011
                           K+ +IL  Y   + ++GY QGM+DL SP+ V   DE+  FW F  
Sbjct: 504  DDEFDVSNITNPHLFKMREILLTYNEHNVNLGYVQGMTDLLSPLYVTFQDESLTFWAFVN 563

Query: 1012 LMRRLRGNFRCTDQSVGVANQLQHLASIIQVLDPKLHDHLETLGGGDYLFAFRMFMVLFR 1191
             M R+  NF   DQS G+ NQ+  L  ++Q + P L  HLE     D  F FRM +V F+
Sbjct: 564  FMDRMERNF-LRDQS-GMKNQMLTLNELVQFMLPDLFKHLEKCESTDLYFFFRMLLVWFK 621

Query: 1192 REVSFGDSLYLWEMMWALEYDPD--IFFA 1272
            RE  +   L LWE++W   Y     +FFA
Sbjct: 622  REFEWSSVLSLWEILWTDYYSGQFHLFFA 650

---

>O43147:RUTB1_HUMAN RUN and TBC1 domain-containing protein 1 - Homo sapiens (Human)|
          Length = 1006

 Score =  101 bits (251), Expect = 1e-20
 Identities = 56/155 (36%), Positives = 88/155 (56%), Gaps = 3/155 (1%)
 Frame = +1

Query: 796  LTLHQIGLDVLRTDRTMVFYENKENLSKLWDILAVYAWIDKDVGYCQGMSDLCSPMIVLL 975
            L LH+I  DV R DR   +Y    NL +L D++  Y W   DVGY QGM DL +P++V L
Sbjct: 792  LNLHRIDKDVQRCDRNY-WYFTPPNLERLRDVMCSYVWEHLDVGYVQGMCDLLAPLLVTL 850

Query: 976  NDEADAFWCFEKLMRRLRGNFRCTDQSVGVANQLQHLASIIQVLDPKLHDHLETLGGGDY 1155
            +++  A+ CF  LM+R+  NF        +     ++ S+IQ+LD +L + +     GDY
Sbjct: 851  DNDQLAYSCFSHLMKRMSQNF---PNGGAMDTHFANMRSLIQILDSELFELMHQ--NGDY 905

Query: 1156 ---LFAFRMFMVLFRREVSFGDSLYLWEMMWALEY 1251
                F +R F++ F+RE+ + D   +WE++WA  +
Sbjct: 906  THFYFCYRWFLLDFKRELLYEDVFAVWEVIWAARH 940

---

>Q8TBP0:TBC16_HUMAN TBC1 domain family member 16 - Homo sapiens (Human)|
          Length = 767

 Score = 94.7 bits (234), Expect = 1e-18
 Identities = 56/163 (34%), Positives = 87/163 (53%), Gaps = 4/163 (2%)
 Frame = +1

Query: 790  WKLTLHQIGLDVLRTDRTMVFY--ENKENLSKLWDILAVYAWIDKDVGYCQGMSDLCSPM 963
            W+     +  DV+RTDR   F+  E+  N+  +  IL  YA  +  VGY QGMSDL +P+
Sbjct: 481  WRNVQFTVDKDVVRTDRNNQFFRGEDNPNVESMRRILLNYAVYNPAVGYSQGMSDLVAPI 540

Query: 964  IVLLNDEADAFWCFEKLMRRLRGNFRCTDQSVGVANQLQHLASIIQVLDPKLHDHLETLG 1143
            +  + DE+D FWCF  LM+     F  + +   +  QL +L  ++++   + + HL +LG
Sbjct: 541  LAEVLDESDTFWCFVGLMQNT--IFVSSPRDEDMEKQLLYLRELLRLTHVRFYQHLVSLG 598

Query: 1144 --GGDYLFAFRMFMVLFRREVSFGDSLYLWEMMWALEYDPDIF 1266
              G   LF  R  ++ F+RE    ++L +WE  WA  Y  D F
Sbjct: 599  EDGLQMLFCHRWLLLCFKREFPEAEALRIWEACWA-HYQTDYF 640



 Score = 32.0 bits (71), Expect = 9.2
 Identities = 20/54 (37%), Positives = 27/54 (50%), Gaps = 1/54 (1%)
 Frame = +1

Query: 361 KTLSVRKWQAAFNPDGCLDIASVLSR-IQKGGVHPTVRGEVWEFLLGCFDPRST 519
           K L V  W    N  G ++    L + I  GG+  ++RGEVW FLL  +   ST
Sbjct: 394 KRLGVSAWLNHLNELGQVEEEYKLRKAIFFGGIDVSIRGEVWPFLLRYYSHEST 447

---

>Q08484:GYP1_YEAST GTPase-activating protein GYP1 - Saccharomyces cerevisiae (Baker's|
            yeast)
          Length = 637

 Score = 66.6 bits (161), Expect = 3e-10
 Identities = 46/172 (26%), Positives = 77/172 (44%), Gaps = 28/172 (16%)
 Frame = +1

Query: 799  TLHQIGLDVLRTDRTMVFYENKENLSKLWDILAVYAWIDKDVGYCQGMSDLCSPMI---- 966
            T HQI +D+ RT+  +  Y+ K   + L  IL ++A      GY QG++DL +P      
Sbjct: 333  TWHQIEIDIPRTNPHIPLYQFKSVQNSLQRILYLWAIRHPASGYVQGINDLVTPFFETFL 392

Query: 967  -----------VLLND-------------EADAFWCFEKLMRRLRGNFRCTDQSVGVANQ 1074
                       V + D             EAD FWC  KL+ ++  N+       G+  Q
Sbjct: 393  TEYLPPSQIDDVEIKDPSTYMVDEQITDLEADTFWCLTKLLEQITDNY--IHGQPGILRQ 450

Query: 1075 LQHLASIIQVLDPKLHDHLETLGGGDYLFAFRMFMVLFRREVSFGDSLYLWE 1230
            +++L+ +++ +D  L++H +        FAFR    L  RE   G  + +W+
Sbjct: 451  VKNLSQLVKRIDADLYNHFQNEHVEFIQFAFRWMNCLLMREFQMGTVIRMWD 502

---

>Q80XC3:US6NL_MOUSE USP6 N-terminal-like protein - Mus musculus (Mouse)|
          Length = 819

 Score = 59.7 bits (143), Expect = 4e-08
 Identities = 41/150 (27%), Positives = 72/150 (48%), Gaps = 6/150 (4%)
 Frame = +1

Query: 802  LHQIGLDVLRTDRTMVFYENKENLSK--LWDILAVYAWIDKDVGYCQGMSDLCSPMIVLL 975
            + QI LDV RT R  + + ++  + +  L+ +LA Y+  + +VGYCQGMS + + +++ +
Sbjct: 141  IRQIDLDVNRTFRDHIMFRDRYGVKQQSLFHVLAAYSIYNTEVGYCQGMSQITALLLMYM 200

Query: 976  NDEADAFWCFEKLM----RRLRGNFRCTDQSVGVANQLQHLASIIQVLDPKLHDHLETLG 1143
            N+E DAFW   KL       + G F        +    +H   I+     KL  HL++  
Sbjct: 201  NEE-DAFWALVKLFSGPKHAMHGFF--VQGFPKLLRFQEHHEKILNKFLSKLKQHLDSQE 257

Query: 1144 GGDYLFAFRMFMVLFRREVSFGDSLYLWEM 1233
                 +  + F   F     F  +L +W++
Sbjct: 258  IYTSFYTMKWFFQCFLDRTPFRLNLRIWDI 287

---

>Q92738:US6NL_HUMAN USP6 N-terminal-like protein - Homo sapiens (Human)|
          Length = 828

 Score = 59.7 bits (143), Expect = 4e-08
 Identities = 41/150 (27%), Positives = 72/150 (48%), Gaps = 6/150 (4%)
 Frame = +1

Query: 802  LHQIGLDVLRTDRTMVFYENKENLSK--LWDILAVYAWIDKDVGYCQGMSDLCSPMIVLL 975
            + QI LDV RT R  + + ++  + +  L+ +LA Y+  + +VGYCQGMS + + +++ +
Sbjct: 141  IRQIDLDVNRTFRDHIMFRDRYGVKQQSLFHVLAAYSIYNTEVGYCQGMSQITALLLMYM 200

Query: 976  NDEADAFWCFEKLM----RRLRGNFRCTDQSVGVANQLQHLASIIQVLDPKLHDHLETLG 1143
            N+E DAFW   KL       + G F        +    +H   I+     KL  HL++  
Sbjct: 201  NEE-DAFWALVKLFSGPKHAMHGFF--VQGFPKLLRFQEHHEKILNKFLSKLKQHLDSQE 257

Query: 1144 GGDYLFAFRMFMVLFRREVSFGDSLYLWEM 1233
                 +  + F   F     F  +L +W++
Sbjct: 258  IYTSFYTMKWFFQCFLDRTPFTLNLRIWDI 287

---

>Q8BM85:TBCK_MOUSE TBC domain-containing protein kinase-like protein - Mus musculus|
            (Mouse)
          Length = 762

 Score = 59.7 bits (143), Expect = 4e-08
 Identities = 39/147 (26%), Positives = 66/147 (44%), Gaps = 1/147 (0%)
 Frame = +1

Query: 799  TLHQIGLDVLRTDRTMVFYENKENLSKLWDILAVYAWIDKDVGYCQGMSDLCSPMIVL-L 975
            T  QI +D+ R  +      + E  +K   +L  +     D+ Y QG+  LC+P + L  
Sbjct: 501  TDRQIEVDIPRCHQYDELLSSPEGHAKFRRVLKAWVVSHPDLVYWQGLDSLCAPFLYLNF 560

Query: 976  NDEADAFWCFEKLMRRLRGNFRCTDQSVGVANQLQHLASIIQVLDPKLHDHLETLGGGDY 1155
            N+EA A+ C    + +   NF   D S  +   L   + +I   DP+L +HL  +G    
Sbjct: 561  NNEALAYACMSAFIPKYLYNFFLKDNSHVIQEYLTVFSQMIAFHDPELSNHLNEIGFIPD 620

Query: 1156 LFAFRMFMVLFRREVSFGDSLYLWEMM 1236
            L+A   F+ +F          +LW+ +
Sbjct: 621  LYAIPWFLTMFTHVFPLHKIFHLWDTL 647

---

>Q8TEA7:TBCK_HUMAN TBC domain-containing protein kinase-like protein - Homo sapiens|
            (Human)
          Length = 893

 Score = 59.7 bits (143), Expect = 4e-08
 Identities = 39/147 (26%), Positives = 66/147 (44%), Gaps = 1/147 (0%)
 Frame = +1

Query: 799  TLHQIGLDVLRTDRTMVFYENKENLSKLWDILAVYAWIDKDVGYCQGMSDLCSPMIVL-L 975
            T  QI +D+ R  +      + E  +K   +L  +     D+ Y QG+  LC+P + L  
Sbjct: 501  TDRQIEVDIPRCHQYDELLSSPEGHAKFRRVLKAWVVSHPDLVYWQGLDSLCAPFLYLNF 560

Query: 976  NDEADAFWCFEKLMRRLRGNFRCTDQSVGVANQLQHLASIIQVLDPKLHDHLETLGGGDY 1155
            N+EA A+ C    + +   NF   D S  +   L   + +I   DP+L +HL  +G    
Sbjct: 561  NNEALAYACMSAFIPKYLYNFFLKDNSHVIQEYLTVFSQMIAFHDPELSNHLNEIGFIPD 620

Query: 1156 LFAFRMFMVLFRREVSFGDSLYLWEMM 1236
            L+A   F+ +F          +LW+ +
Sbjct: 621  LYAIPWFLTMFTHVFPLHKIFHLWDTL 647

---

>Q5F361:TBCK_CHICK TBC domain-containing protein kinase-like protein - Gallus gallus|
            (Chicken)
          Length = 893

 Score = 59.7 bits (143), Expect = 4e-08
 Identities = 39/147 (26%), Positives = 66/147 (44%), Gaps = 1/147 (0%)
 Frame = +1

Query: 799  TLHQIGLDVLRTDRTMVFYENKENLSKLWDILAVYAWIDKDVGYCQGMSDLCSPMIVL-L 975
            T  QI +D+ R  +      + E  +K   +L  +     D+ Y QG+  LC+P + L  
Sbjct: 501  TDRQIEVDIPRCHQYDELLSSPEGHAKFRRVLKAWVVSHPDLVYWQGLDSLCAPFLYLNF 560

Query: 976  NDEADAFWCFEKLMRRLRGNFRCTDQSVGVANQLQHLASIIQVLDPKLHDHLETLGGGDY 1155
            N+EA A+ C    + +   NF   D S  +   L   + +I   DP+L +HL  +G    
Sbjct: 561  NNEALAYACMSAFIPKYLYNFFLKDNSHVIQEYLTVFSQMIAFHDPELSNHLNEIGFIPD 620

Query: 1156 LFAFRMFMVLFRREVSFGDSLYLWEMM 1236
            L+A   F+ +F          +LW+ +
Sbjct: 621  LYAIPWFLTMFTHVFPLHKIFHLWDTL 647

---

>Q8R3D1:TBC13_MOUSE TBC1 domain family member 13 - Mus musculus (Mouse)|
          Length = 400

 Score = 59.7 bits (143), Expect = 4e-08
 Identities = 35/130 (26%), Positives = 63/130 (48%), Gaps = 12/130 (9%)
 Frame = +1

Query: 889  ILAVYAWIDKDVGYCQGMSDLCSPMIVLL----------NDEADAFWCFEKLMRRLRGNF 1038
            IL +YA ++  + Y QGM+++  P+              + EAD F+CF  LM  +R NF
Sbjct: 214  ILFIYAKLNPGIAYVQGMNEIVGPLYYTFATDPNSEWKEHAEADTFFCFTNLMAEIRDNF 273

Query: 1039 --RCTDQSVGVANQLQHLASIIQVLDPKLHDHLETLGGGDYLFAFRMFMVLFRREVSFGD 1212
                 D   G+  +++ + S ++  D +L+  L+        FAFR   +L  +E    D
Sbjct: 274  IKSLDDSQCGITYKMEKVYSTLKDKDVELYLKLQEQSIKPQFFAFRWLTLLLSQEFLLPD 333

Query: 1213 SLYLWEMMWA 1242
             + +W+ ++A
Sbjct: 334  VIRIWDSLFA 343

---

>Q95LL3:TB22B_MACFA TBC1 domain family member 22B - Macaca fascicularis (Crab eating|
            macaque) (Cynomolgus monkey)
          Length = 505

 Score = 58.9 bits (141), Expect = 7e-08
 Identities = 42/167 (25%), Positives = 73/167 (43%), Gaps = 23/167 (13%)
 Frame = +1

Query: 799  TLHQIGLDVLRTDRTMVFYENKENLSKLWDILAVYAWIDKDVGYCQGMSDLCSPMIV--- 969
            T  QI +D+ RT+  +  ++          IL ++A      GY QG++DL +P  V   
Sbjct: 264  TYRQIHIDIPRTNPLIPLFQQPLVQEIFERILFIWAIRHPASGYVQGINDLVTPFFVVFL 323

Query: 970  --------------------LLNDEADAFWCFEKLMRRLRGNFRCTDQSVGVANQLQHLA 1089
                                L + EAD+FWC  KL+  ++ N+  T    G+  +++ L 
Sbjct: 324  SEYVEEDVENFDVTNLSQDMLRSIEADSFWCMSKLLDGIQDNY--TFAQPGIQKKVKALE 381

Query: 1090 SIIQVLDPKLHDHLETLGGGDYLFAFRMFMVLFRREVSFGDSLYLWE 1230
             ++  +D ++H+H          FAFR    L  RE+    ++ LW+
Sbjct: 382  ELVSRIDEQVHNHFRRYEVEYLQFAFRWMNNLLMRELPLRCTIRLWD 428

---

>Q9NU19:TB22B_HUMAN TBC1 domain family member 22B - Homo sapiens (Human)|
          Length = 505

 Score = 58.9 bits (141), Expect = 7e-08
 Identities = 42/167 (25%), Positives = 73/167 (43%), Gaps = 23/167 (13%)
 Frame = +1

Query: 799  TLHQIGLDVLRTDRTMVFYENKENLSKLWDILAVYAWIDKDVGYCQGMSDLCSPMIV--- 969
            T  QI +D+ RT+  +  ++          IL ++A      GY QG++DL +P  V   
Sbjct: 264  TYRQIHIDIPRTNPLIPLFQQPLVQEIFERILFIWAIRHPASGYVQGINDLVTPFFVVFL 323

Query: 970  --------------------LLNDEADAFWCFEKLMRRLRGNFRCTDQSVGVANQLQHLA 1089
                                L + EAD+FWC  KL+  ++ N+  T    G+  +++ L 
Sbjct: 324  SEYVEEDVENFDVTNLSQDMLRSIEADSFWCMSKLLDGIQDNY--TFAQPGIQKKVKALE 381

Query: 1090 SIIQVLDPKLHDHLETLGGGDYLFAFRMFMVLFRREVSFGDSLYLWE 1230
             ++  +D ++H+H          FAFR    L  RE+    ++ LW+
Sbjct: 382  ELVSRIDEQVHNHFRRYEVEYLQFAFRWMNNLLMRELPLRCTIRLWD 428

---

>Q755I4:GYP5_ASHGO GTPase-activating protein GYP5 - Ashbya gossypii (Yeast)|
            (Eremothecium gossypii)
          Length = 829

 Score = 58.9 bits (141), Expect = 7e-08
 Identities = 33/125 (26%), Positives = 66/125 (52%)
 Frame = +1

Query: 865  ENLSKLWDILAVYAWIDKDVGYCQGMSDLCSPMIVLLNDEADAFWCFEKLMRRLRGNFRC 1044
            +    L+++L  Y+  D +VGY QGM+ + +P+++ + +EADAF    KLM+        
Sbjct: 423  DKTESLFNVLKAYSLFDPEVGYTQGMAFVTAPLLINVWEEADAFGLLIKLMKNYGLREFF 482

Query: 1045 TDQSVGVANQLQHLASIIQVLDPKLHDHLETLGGGDYLFAFRMFMVLFRREVSFGDSLYL 1224
                 G+  +L     +++   P+L++HL  LG    ++A + F+ LF  +   G  L +
Sbjct: 483  LPDMPGLQLKLYEFDRLLEENSPQLYNHLIRLGIRSSMYATQWFLTLFAYKFPLGFVLRI 542

Query: 1225 WEMMW 1239
             ++++
Sbjct: 543  LDVIF 547

---

>Q8WUA7:TB22A_HUMAN TBC1 domain family member 22A - Homo sapiens (Human)|
          Length = 517

 Score = 58.2 bits (139), Expect = 1e-07
 Identities = 47/181 (25%), Positives = 82/181 (45%), Gaps = 25/181 (13%)
 Frame = +1

Query: 799  TLHQIGLDVLRTDRTMVFYENKENLSKLWD-ILAVYAWIDKDVGYCQGMSDLCSPMIV-- 969
            T  QI +D+ R     +  + K  ++++++ IL ++A      GY QG++DL +P  V  
Sbjct: 276  TYRQIHIDIPRMSPEALILQPK--VTEIFERILFIWAIRHPASGYVQGINDLVTPFFVVF 333

Query: 970  ----------------------LLNDEADAFWCFEKLMRRLRGNFRCTDQSVGVANQLQH 1083
                                  L N EAD +WC  KL+  ++ N+  T    G+  +++ 
Sbjct: 334  ICEYIEAEEVDTVDVSGVPAEVLCNIEADTYWCMSKLLDGIQDNY--TFAQPGIQMKVKM 391

Query: 1084 LASIIQVLDPKLHDHLETLGGGDYLFAFRMFMVLFRREVSFGDSLYLWEMMWALEYDPDI 1263
            L  ++  +D ++H HL+        FAFR    L  REV    ++ LW+     + +PD 
Sbjct: 392  LEELVSRIDEQVHRHLDQHEVRYLQFAFRWMNNLLMREVPLRCTIRLWD---TYQSEPDG 448

Query: 1264 F 1266
            F
Sbjct: 449  F 449

---

>Q09830:YAD4_SCHPO Uncharacterized protein C4G8.04 - Schizosaccharomyces pombe (Fission|
            yeast)
          Length = 772

 Score = 57.4 bits (137), Expect = 2e-07
 Identities = 42/150 (28%), Positives = 75/150 (50%), Gaps = 2/150 (1%)
 Frame = +1

Query: 808  QIGLDVLRTDRTMVFYENK-ENLSKLWDILAVYAWIDKDVGYCQGMSDLCSPMIVLLNDE 984
            QI +D+ RT    VF+  K   + KL  IL  Y+  +  +GYCQGM+ + + +++L   E
Sbjct: 546  QIDMDINRTMAKNVFFGGKGPGIPKLRRILVAYSRHNPHIGYCQGMNVIGAFLLLLYASE 605

Query: 985  ADAFWCFEKLMRR-LRGNFRCTDQSVGVANQLQHLASIIQVLDPKLHDHLETLGGGDYLF 1161
             DAF+    ++   L   +   D     A+QL  L S ++   P+++ HLE LG      
Sbjct: 606  EDAFYMLMSIIENVLPPKYFTPDLMTSRADQLV-LKSFVKESLPEIYSHLELLGVDLDAI 664

Query: 1162 AFRMFMVLFRREVSFGDSLYLWEMMWALEY 1251
            +F  F+ ++   +    S  +++M++   Y
Sbjct: 665  SFHWFLSVYTDTLPTNISFRIFDMLFCDGY 694

---

>Q95KI1:TB22A_MACFA TBC1 domain family member 22A - Macaca fascicularis (Crab eating|
            macaque) (Cynomolgus monkey)
          Length = 497

 Score = 57.0 bits (136), Expect = 3e-07
 Identities = 44/169 (26%), Positives = 77/169 (45%), Gaps = 25/169 (14%)
 Frame = +1

Query: 799  TLHQIGLDVLRTDRTMVFYENKENLSKLWD-ILAVYAWIDKDVGYCQGMSDLCSPMIV-- 969
            T  QI +D+ R     +  + K  ++++++ IL ++A      GY QG++DL +P  V  
Sbjct: 256  TYRQIHIDIPRMSPEALILQPK--VTEIFERILFIWAIRHPASGYVQGINDLVTPFFVVF 313

Query: 970  ----------------------LLNDEADAFWCFEKLMRRLRGNFRCTDQSVGVANQLQH 1083
                                  L N EAD +WC  KL+  ++ N+  T    G+  +++ 
Sbjct: 314  ICEYIEAEEVDTVDVSGVPAEVLRNIEADTYWCMSKLLDGIQDNY--TFAQPGIQMKVKM 371

Query: 1084 LASIIQVLDPKLHDHLETLGGGDYLFAFRMFMVLFRREVSFGDSLYLWE 1230
            L  ++  +D ++H HL+        FAFR    L  REV    ++ LW+
Sbjct: 372  LEELVSRIDEQVHRHLDQHEVRYLQFAFRWMNNLLMREVPLRCTIRLWD 420

---

>Q8R5A6:TB22A_MOUSE TBC1 domain family member 22A - Mus musculus (Mouse)|
          Length = 516

 Score = 55.8 bits (133), Expect = 6e-07
 Identities = 43/169 (25%), Positives = 77/169 (45%), Gaps = 25/169 (14%)
 Frame = +1

Query: 799  TLHQIGLDVLRTDRTMVFYENKENLSKLWD-ILAVYAWIDKDVGYCQGMSDLCSPMIV-- 969
            T  QI +D+ R     +  + K  ++++++ IL ++A      GY QG++DL +P  V  
Sbjct: 275  TYRQIHIDIPRMSPEALILQPK--VTEIFERILFIWAIRHPASGYVQGINDLVTPFFVVF 332

Query: 970  ----------------------LLNDEADAFWCFEKLMRRLRGNFRCTDQSVGVANQLQH 1083
                                  L N EAD +WC  KL+  ++ N+  T    G+  +++ 
Sbjct: 333  ICEYTDREDVDKVDVSSVPAEVLRNIEADTYWCMSKLLDGIQDNY--TFAQPGIQMKVKM 390

Query: 1084 LASIIQVLDPKLHDHLETLGGGDYLFAFRMFMVLFRREVSFGDSLYLWE 1230
            L  ++  +D ++H HL+        FAFR    L  RE+    ++ LW+
Sbjct: 391  LEELVSRIDERVHRHLDGHEVRYLQFAFRWMNNLLMRELPLRCTIRLWD 439

---

>Q6GL87:GRPT1_XENTR Growth hormone regulated TBC protein 1 - Xenopus tropicalis (Western|
            clawed frog) (Silurana tropicalis)
          Length = 342

 Score = 55.8 bits (133), Expect = 6e-07
 Identities = 39/149 (26%), Positives = 72/149 (48%), Gaps = 8/149 (5%)
 Frame = +1

Query: 817  LDVLRTDRTMVFYEN-------KENLSK-LWDILAVYAWIDKDVGYCQGMSDLCSPMIVL 972
            LD++ TD    F +N         +L K L+++L  Y   +K VGYCQGM+ +   +I++
Sbjct: 113  LDLVITDLNRTFPDNVLFQKNANPSLQKDLYNVLVAYGQHNKTVGYCQGMNFIAGYLILV 172

Query: 973  LNDEADAFWCFEKLMRRLRGNFRCTDQSVGVANQLQHLASIIQVLDPKLHDHLETLGGGD 1152
              DE  AFW  + L+ ++  ++  +    G+    + L  +++   P +   +ET G   
Sbjct: 173  TKDEEKAFWLMDALIGQILPDY-YSPAMTGLKTDQEVLGDLVKKKIPSVAQLIETHGVMW 231

Query: 1153 YLFAFRMFMVLFRREVSFGDSLYLWEMMW 1239
             L   R F+ LF   +     L +W+ ++
Sbjct: 232  TLLVSRWFICLFIDILPVETVLRIWDCLF 260

---

>Q5TC63:GRTP1_HUMAN Growth hormone-regulated TBC protein 1 - Homo sapiens (Human)|
          Length = 336

 Score = 55.5 bits (132), Expect = 8e-07
 Identities = 36/148 (24%), Positives = 72/148 (48%), Gaps = 8/148 (5%)
 Frame = +1

Query: 820  DVLRTDRTMVFYENKENLSK--------LWDILAVYAWIDKDVGYCQGMSDLCSPMIVLL 975
            D +RTD    F +N +            L+++L  Y   ++ VGYCQGM+ +   +I++ 
Sbjct: 109  DAIRTDLNRTFPDNVKFRKTTDPCLQRTLYNVLLAYGHHNQGVGYCQGMNFIAGYLILIT 168

Query: 976  NDEADAFWCFEKLMRRLRGNFRCTDQSVGVANQLQHLASIIQVLDPKLHDHLETLGGGDY 1155
            N+E ++FW  + L+ R+  ++  +   +G+    + L  +++   P +   +E LG    
Sbjct: 169  NNEEESFWLLDALVGRILPDY-YSPAMLGLKTDQEVLGELVRAKLPAVGALMERLGVLWT 227

Query: 1156 LFAFRMFMVLFRREVSFGDSLYLWEMMW 1239
            L   R F+ LF   +     L +W+ ++
Sbjct: 228  LLVSRWFICLFVDILPVETVLRIWDCLF 255

---

>O97790:TBCD1_BOVIN TBC1 domain family member 1 - Bos taurus (Bovine)|
          Length = 556

 Score = 55.1 bits (131), Expect = 1e-06
 Identities = 41/168 (24%), Positives = 83/168 (49%), Gaps = 2/168 (1%)
 Frame = +1

Query: 805  HQIGLDVLRTDRTMVFYENKENLSKL--WDILAVYAWIDKDVGYCQGMSDLCSPMIVLLN 978
            H I +D+ RT  T  +Y  +    +L  ++IL  Y+ +D++VGYCQG+S +   +++ + 
Sbjct: 234  HAILIDLGRTFPTHPYYSAQLGAGQLSLYNILKAYSLLDQEVGYCQGLSFVAGILLLHMG 293

Query: 979  DEADAFWCFEKLMRRLRGNFRCTDQSVGVANQLQHLASIIQVLDPKLHDHLETLGGGDYL 1158
            +E +AF   + LM  +    +     + +  Q+  L+ ++      L++HLE    G  L
Sbjct: 294  EE-EAFNMLKFLMFDMGLRKQYRPDMIILQIQMYQLSRLLHDYHRDLYNHLEEHEIGPSL 352

Query: 1159 FAFRMFMVLFRREVSFGDSLYLWEMMWALEYDPDIFFAACEEASGAHK 1302
            +A   F+ +F  +   G    +++M++      ++ F       G+HK
Sbjct: 353  YAAPWFLTVFASQFPLGFVARVFDMIFL--QGSEVIFKVALSLLGSHK 398

---

>Q86TI0:TBCD1_HUMAN TBC1 domain family member 1 - Homo sapiens (Human)|
          Length = 1168

 Score = 54.7 bits (130), Expect = 1e-06
 Identities = 40/168 (23%), Positives = 84/168 (50%), Gaps = 2/168 (1%)
 Frame = +1

Query: 805  HQIGLDVLRTDRTMVFYENKENLSKL--WDILAVYAWIDKDVGYCQGMSDLCSPMIVLLN 978
            H I +D+ RT  T  ++  +    +L  ++IL  Y+ +D++VGYCQG+S +   +++ ++
Sbjct: 846  HAILIDLGRTFPTHPYFSAQLGAGQLSLYNILKAYSLLDQEVGYCQGLSFVAGILLLHMS 905

Query: 979  DEADAFWCFEKLMRRLRGNFRCTDQSVGVANQLQHLASIIQVLDPKLHDHLETLGGGDYL 1158
            +E +AF   + LM  +    +     + +  Q+  L+ ++      L++HLE    G  L
Sbjct: 906  EE-EAFKMLKFLMFDMGLRKQYRPDMIILQIQMYQLSRLLHDYHRDLYNHLEEHEIGPSL 964

Query: 1159 FAFRMFMVLFRREVSFGDSLYLWEMMWALEYDPDIFFAACEEASGAHK 1302
            +A   F+ +F  +   G    +++M++      ++ F       G+HK
Sbjct: 965  YAAPWFLTMFASQFPLGFVARVFDMIFL--QGTEVIFKVALSLLGSHK 1010

---

>Q8IYX1:TBC21_HUMAN TBC1 domain family member 21 - Homo sapiens (Human)|
          Length = 336

 Score = 54.7 bits (130), Expect = 1e-06
 Identities = 88/411 (21%), Positives = 164/411 (39%), Gaps = 3/411 (0%)
 Frame = +1

Query: 349  IKAGKTLSVRKWQAAFNPDGCLDIAS--VLSRIQKGGVHPTVRGEVWEFLLGCFDPRSTF 522
            +K    +   +W + F+  G L  +   +   I + G+HP VR E W+FL G F  +S+ 
Sbjct: 21   VKRKPPIDKTEWDSFFDESGHLAKSRDFICVNILERGLHPFVRTEAWKFLTGYFSWQSSQ 80

Query: 523  DXXXXXXXXXXLQYARWKEECREMDSHVGSGKVITAPLITEDGRPIKDPLVLLEATSNQN 702
            D          ++   +K  C+                + E  +P+ + L       ++N
Sbjct: 81   D---ERLTVDSMRRKNYKALCQ----------------MYEKIQPLLENL-------HRN 114

Query: 703  TSDGASTSSNNGIEVDDSAERITDKQIIEWKLTLHQIGLDVLRTDRTMVFYENKENLSKL 882
                  T + N I  D   ++I DK        L  + +D  R ++ ++       LS +
Sbjct: 115  -----FTETRNNIARD--IQKIYDKD------PLGNVLIDKKRLEKILL-------LSYV 154

Query: 883  WDILAVYAWIDKDVGYCQGMSDLCSPMIVLLNDEADAFWCFEKLMRRLRGNFRCTDQSVG 1062
             +  A Y          QG  ++     +++  + + FW F+  +++   +  C   ++G
Sbjct: 155  CNTQAEYQ---------QGFHEMMMLFQLMVEHDHETFWLFQFFLQKTEHS--CV-INIG 202

Query: 1063 VANQLQHLASIIQVLDPKLHDHLETLGGGDYLFAFRMFMVLFRREV-SFGDSLYLWEMMW 1239
            VA  L  L+++I  LDP   +HL+  G G     F  F   F+R   SF D   LWE++ 
Sbjct: 203  VAKNLDMLSTLITFLDPVFAEHLKGKGAGAVQSLFPWFCFCFQRAFKSFDDVWRLWEVL- 261

Query: 1240 ALEYDPDIFFAACEEASGAHKKVSKSKLRGVRHFAKWDKDKDKDVPEETDGPVPISVFMV 1419
                            +G          +  R+F                      V + 
Sbjct: 262  ---------------LTG----------KPCRNF---------------------QVLVA 275

Query: 1420 ASVLKEKREKLLQEARGLDDLIRILNDVNGNLDAKKACAGALKLHKKYLKK 1572
             S+L+  RE++LQE+ G DD++   N++  +LDA +  + A  ++ + ++K
Sbjct: 276  YSMLQMVREQVLQESMGGDDILLACNNLI-DLDADELISAACVVYAELIQK 325

---

>Q60949:TBCD1_MOUSE TBC1 domain family member 1 - Mus musculus (Mouse)|
          Length = 1255

 Score = 54.3 bits (129), Expect = 2e-06
 Identities = 40/168 (23%), Positives = 84/168 (50%), Gaps = 2/168 (1%)
 Frame = +1

Query: 805  HQIGLDVLRTDRTMVFYENKENLSKL--WDILAVYAWIDKDVGYCQGMSDLCSPMIVLLN 978
            H I +D+ RT  T  ++  +    +L  ++IL  Y+ +D++VGYCQG+S +   +++ ++
Sbjct: 933  HAILIDLGRTFPTHPYFSAQLGAGQLSLYNILKAYSLLDQEVGYCQGLSFVAGILLLHMS 992

Query: 979  DEADAFWCFEKLMRRLRGNFRCTDQSVGVANQLQHLASIIQVLDPKLHDHLETLGGGDYL 1158
            +E +AF   + LM  +    +     + +  Q+  L+ ++      L++HLE    G  L
Sbjct: 993  EE-EAFKMLKFLMFDMGLRKQYRPDMIILQIQMYQLSRLLHDYHRDLYNHLEEHEIGPSL 1051

Query: 1159 FAFRMFMVLFRREVSFGDSLYLWEMMWALEYDPDIFFAACEEASGAHK 1302
            +A   F+ +F  +   G    +++M++      ++ F       G+HK
Sbjct: 1052 YAAPWFLTVFASQFPLGFVARVFDMIFL--QGSEVIFKVALSLLGSHK 1097

---

>Q6GLZ0:GRTP1_XENLA Growth hormone regulated TBC protein 1 - Xenopus laevis (African|
            clawed frog)
          Length = 342

 Score = 54.3 bits (129), Expect = 2e-06
 Identities = 38/149 (25%), Positives = 71/149 (47%), Gaps = 8/149 (5%)
 Frame = +1

Query: 817  LDVLRTDRTMVFYENKE-------NLSK-LWDILAVYAWIDKDVGYCQGMSDLCSPMIVL 972
            LD++ TD    F +N +       +L K L+++L  Y   +  VGYCQGM+ +   +I++
Sbjct: 113  LDLVNTDLNRTFPDNVQFRKNSNPSLQKHLYNVLVAYGQHNTTVGYCQGMNFIAGYLILV 172

Query: 973  LNDEADAFWCFEKLMRRLRGNFRCTDQSVGVANQLQHLASIIQVLDPKLHDHLETLGGGD 1152
              DE  AFW  + L+ R+  ++  +    G+    + L  +++   P +   +E  G   
Sbjct: 173  TKDEEKAFWLMDALIGRILPDY-YSPAMTGLKTDQEVLGDLVKKKLPAVSQLIEAHGVMW 231

Query: 1153 YLFAFRMFMVLFRREVSFGDSLYLWEMMW 1239
             L   R F+ LF   +     L +W+ ++
Sbjct: 232  TLLVSRWFICLFIDILPVETVLRIWDCLF 260

---

>Q6PBU5:GRPT1_DANRE Growth hormone regulated TBC protein 1 - Danio rerio (Zebrafish)|
            (Brachydanio rerio)
          Length = 356

 Score = 54.3 bits (129), Expect = 2e-06
 Identities = 31/120 (25%), Positives = 61/120 (50%)
 Frame = +1

Query: 880  LWDILAVYAWIDKDVGYCQGMSDLCSPMIVLLNDEADAFWCFEKLMRRLRGNFRCTDQSV 1059
            L+++L  Y   +K VGYCQGM+ +   +I++  DE  +FW  E L+ R+  ++  T   +
Sbjct: 156  LYNVLVAYGHHNKAVGYCQGMNFIAGYLILVSKDEETSFWLMEALLSRILPDY-YTPAML 214

Query: 1060 GVANQLQHLASIIQVLDPKLHDHLETLGGGDYLFAFRMFMVLFRREVSFGDSLYLWEMMW 1239
            G+    + L  ++++  P +   ++  G    L   R F+ LF   +     L +W+ ++
Sbjct: 215  GLKTDQEVLGELVRLKAPAVWKLMQDQGVMWTLVVSRWFICLFIDVLPVETVLRIWDCLF 274

---

>O60447:EVI5_HUMAN Ecotropic viral integration site 5 protein homolog - Homo sapiens|
            (Human)
          Length = 810

 Score = 53.5 bits (127), Expect = 3e-06
 Identities = 35/127 (27%), Positives = 71/127 (55%), Gaps = 4/127 (3%)
 Frame = +1

Query: 820  DVLRTDRTMVFYENKENLSK--LWDILAVYAWIDKDVGYCQGMSDLCSPMIVLLNDEADA 993
            D+ RT     F++ K++L +  L++++  Y+ +D++VGYCQG + +   +++ + +E +A
Sbjct: 205  DIARTYPEHNFFKEKDSLGQEVLFNVMKAYSLVDREVGYCQGSAFIVGLLLMQMPEE-EA 263

Query: 994  FWCFEKLMR--RLRGNFRCTDQSVGVANQLQHLASIIQVLDPKLHDHLETLGGGDYLFAF 1167
            F  F KLM+  RLR  F+ +   +G+   +     +IQ   P+L  H ++      ++A 
Sbjct: 264  FCVFVKLMQDYRLRELFKPSMAELGLC--MYQFECMIQEHLPELFVHFQSQSFHTSMYAS 321

Query: 1168 RMFMVLF 1188
              F+ +F
Sbjct: 322  SWFLTIF 328

---

>Q9BYX2:TBCD2_HUMAN TBC1 domain family member 2 - Homo sapiens (Human)|
          Length = 917

 Score = 52.8 bits (125), Expect = 5e-06
 Identities = 39/149 (26%), Positives = 68/149 (45%), Gaps = 8/149 (5%)
 Frame = +1

Query: 808  QIGLDVLRTDRTMVFYENKENL-------SKLWDILAVYAWIDKDVGYCQGMSDLCSPMI 966
            QI LD+ RT     F  NK           KL  +L  ++W +  +GYCQG++ L +  +
Sbjct: 669  QIELDLNRT-----FPNNKHFTCPTSSFPDKLRRVLLAFSWQNPTIGYCQGLNRLAAIAL 723

Query: 967  VLLNDEADAFWCFEKLMRRLR-GNFRCTDQSVGVANQLQHLASIIQVLDPKLHDHLETLG 1143
            ++L +E  AFWC   ++  +   ++ C   +    +Q + L  ++    P+L  HL    
Sbjct: 724  LVLEEEESAFWCLVAIVETIMPADYYCNTLTASQVDQ-RVLQDLLSEKLPRLMAHLGQHH 782

Query: 1144 GGDYLFAFRMFMVLFRREVSFGDSLYLWE 1230
                L  F  F+V+F   +     L +W+
Sbjct: 783  VDLSLVTFNWFLVVFADSLISNILLRVWD 811

---

>P53258:GYP2_YEAST GTPase-activating protein GYP2 - Saccharomyces cerevisiae (Baker's|
            yeast)
          Length = 950

 Score = 52.8 bits (125), Expect = 5e-06
 Identities = 24/81 (29%), Positives = 47/81 (58%)
 Frame = +1

Query: 760  ERITDKQIIEWKLTLHQIGLDVLRTDRTMVFYENKENLSKLWDILAVYAWIDKDVGYCQG 939
            ERI ++   +    + +I  D+ R+      Y+ +E + +L ++L  Y+W + DVGYCQ 
Sbjct: 272  ERILNENAGKTSQAIDEIEKDLKRSLPEYSAYQTEEGIQRLRNVLTAYSWKNPDVGYCQA 331

Query: 940  MSDLCSPMIVLLNDEADAFWC 1002
            M+ + +  ++ +++E  AFWC
Sbjct: 332  MNIVVAGFLIFMSEE-QAFWC 351

---

>Q4QQU7:GRPT1_RAT Growth hormone-regulated TBC protein 1 - Rattus norvegicus (Rat)|
          Length = 289

 Score = 52.4 bits (124), Expect = 7e-06
 Identities = 41/167 (24%), Positives = 81/167 (48%), Gaps = 9/167 (5%)
 Frame = +1

Query: 766  ITDKQIIEWKLTLHQIG------LDVLRTDRTMVFYENKEN--LSK-LWDILAVYAWIDK 918
            I  K+ I+W   L   G       D+ RT    V +    +  L K L+++L  Y   ++
Sbjct: 43   ILTKRAIKWSKLLKGSGGVRKSVTDLNRTFPDNVMFRKTADPCLQKTLYNVLLAYGLHNQ 102

Query: 919  DVGYCQGMSDLCSPMIVLLNDEADAFWCFEKLMRRLRGNFRCTDQSVGVANQLQHLASII 1098
            DVGYCQGM+ +   +I++  +E ++FW  + L+ R+  ++  +   +G+    + LA ++
Sbjct: 103  DVGYCQGMNFIAGYLILITKNEEESFWLLDALVGRILPDY-YSPAMLGLKTDQEVLAELV 161

Query: 1099 QVLDPKLHDHLETLGGGDYLFAFRMFMVLFRREVSFGDSLYLWEMMW 1239
            ++  P +   ++  G    L   R F+ LF   +     L +W+ ++
Sbjct: 162  RMKLPAVAALMDGHGVLWTLLVSRWFICLFVDILPVETVLRIWDCLF 208

---

>O60343:TBCD4_HUMAN TBC1 domain family member 4 - Homo sapiens (Human)|
          Length = 1298

 Score = 51.6 bits (122), Expect = 1e-05
 Identities = 37/137 (27%), Positives = 70/137 (51%), Gaps = 2/137 (1%)
 Frame = +1

Query: 805  HQIGLDVLRTDRTMVFYENKENLSKL--WDILAVYAWIDKDVGYCQGMSDLCSPMIVLLN 978
            H I +D+ RT  T  ++  +    +L  +++L  Y+ +DK+VGYCQG+S +   +++ ++
Sbjct: 964  HAILVDLGRTFPTHPYFSVQLGPGQLSLFNLLKAYSLLDKEVGYCQGISFVAGVLLLHMS 1023

Query: 979  DEADAFWCFEKLMRRLRGNFRCTDQSVGVANQLQHLASIIQVLDPKLHDHLETLGGGDYL 1158
            +E  AF   + LM  L    +     + +  Q+  L+ ++      L++HLE       L
Sbjct: 1024 EE-QAFEMLKFLMYDLGFRKQYRPDMMSLQIQMYQLSRLLHDYHRDLYNHLEENEISPSL 1082

Query: 1159 FAFRMFMVLFRREVSFG 1209
            +A   F+ LF  + S G
Sbjct: 1083 YAAPWFLTLFASQFSLG 1099

---

>Q8BYJ6:TBCD4_MOUSE TBC1 domain family member 4 - Mus musculus (Mouse)|
          Length = 1307

 Score = 51.2 bits (121), Expect = 1e-05
 Identities = 36/137 (26%), Positives = 70/137 (51%), Gaps = 2/137 (1%)
 Frame = +1

Query: 805  HQIGLDVLRTDRTMVFYENKENLSKL--WDILAVYAWIDKDVGYCQGMSDLCSPMIVLLN 978
            H I +D+ RT  T  ++  +    +L  +++L  Y+ +DK+VGYCQG+S +   +++ ++
Sbjct: 973  HAILVDLGRTFPTHPYFSVQLGAGQLSLFNLLKAYSLLDKEVGYCQGISFVAGVLLLHMS 1032

Query: 979  DEADAFWCFEKLMRRLRGNFRCTDQSVGVANQLQHLASIIQVLDPKLHDHLETLGGGDYL 1158
            +E  AF   + LM  L    +     + +  Q+  L+ ++     +L++HLE       L
Sbjct: 1033 EE-QAFEMLKFLMYDLGFRKQYRPDMMSLQIQMYQLSRLLHDYHRELYNHLEENEISPSL 1091

Query: 1159 FAFRMFMVLFRREVSFG 1209
            +A   F+ LF  +   G
Sbjct: 1092 YAAPWFLTLFASQFPLG 1108

---

>Q96CN4:EVI5L_HUMAN EVI5-like protein - Homo sapiens (Human)|
          Length = 794

 Score = 51.2 bits (121), Expect = 1e-05
 Identities = 33/127 (25%), Positives = 70/127 (55%), Gaps = 4/127 (3%)
 Frame = +1

Query: 820  DVLRTDRTMVFYENKENLSK--LWDILAVYAWIDKDVGYCQGMSDLCSPMIVLLNDEADA 993
            D+ RT     F++ +++L +  L++++  Y+ +D++VGYCQG + +   +++ + +E +A
Sbjct: 157  DIARTYPEHEFFKGQDSLGQEVLFNVMKAYSLVDREVGYCQGSAFIVGLLLMQMPEE-EA 215

Query: 994  FWCFEKLMR--RLRGNFRCTDQSVGVANQLQHLASIIQVLDPKLHDHLETLGGGDYLFAF 1167
            F  F +LM+  RLR  F+ +   +G+   +     ++Q   P L+ H  +      ++A 
Sbjct: 216  FCVFVRLMQEYRLRELFKPSMAELGLC--IYQFEYMLQEQLPDLNTHFRSQSFHTSMYAS 273

Query: 1168 RMFMVLF 1188
              F+ LF
Sbjct: 274  SWFLTLF 280

---

>Q12344:GYP5_YEAST GTPase-activating protein GYP5 - Saccharomyces cerevisiae (Baker's|
            yeast)
          Length = 894

 Score = 50.8 bits (120), Expect = 2e-05
 Identities = 34/149 (22%), Positives = 67/149 (44%)
 Frame = +1

Query: 742  EVDDSAERITDKQIIEWKLTLHQIGLDVLRTDRTMVFYENKENLSKLWDILAVYAWIDKD 921
            E++D  E + D +       LH+     +R D     +  ++ +  L+ ++ VY+  D D
Sbjct: 471  EMEDIYETLLDTEC------LHEA---TIRRDLRRTKFVAEDKMESLYKVIKVYSVYDPD 521

Query: 922  VGYCQGMSDLCSPMIVLLNDEADAFWCFEKLMRRLRGNFRCTDQSVGVANQLQHLASIIQ 1101
            VGY QGM  + +P+++   +EA++F     LM+             G+   L     +++
Sbjct: 522  VGYTQGMGFIAAPLLINCENEAESFGLLVGLMKNYGLRELFLPGMPGLMLMLYQFDRLLE 581

Query: 1102 VLDPKLHDHLETLGGGDYLFAFRMFMVLF 1188
               P L++ L   G    ++A + F+  F
Sbjct: 582  EHSPSLYNRLIREGISSTMYATQWFLTFF 610

---

>Q8IV04:TB10C_HUMAN Carabin - Homo sapiens (Human)|
          Length = 446

 Score = 49.3 bits (116), Expect = 6e-05
 Identities = 31/118 (26%), Positives = 59/118 (50%), Gaps = 1/118 (0%)
 Frame = +1

Query: 880  LWDILAVYAWIDKDVGYCQGMSDLCSPMIVLLNDEADAFWCFEKLMR-RLRGNFRCTDQS 1056
            L  +L  Y     + GYCQ    + + +++ L  E +AFWC  ++    L G +    ++
Sbjct: 160  LLQVLKAYTLYRPEQGYCQAQGPVAAVLLMHLPPE-EAFWCLVQICEVYLPGYYGPHMEA 218

Query: 1057 VGVANQLQHLASIIQVLDPKLHDHLETLGGGDYLFAFRMFMVLFRREVSFGDSLYLWE 1230
            V +  ++    ++++ L P +H HL+ +G G  L+    F+ LF R + F   L +W+
Sbjct: 219  VRLDAEV--FMALLRRLLPHVHKHLQQVGVGPLLYLPEWFLCLFARSLPFPTVLRVWD 274

---

>Q3UYK3:TBCD9_MOUSE TBC1 domain family member 9 - Mus musculus (Mouse)|
          Length = 1264

 Score = 48.5 bits (114), Expect = 9e-05
 Identities = 31/128 (24%), Positives = 66/128 (51%)
 Frame = +1

Query: 760  ERITDKQIIEWKLTLHQIGLDVLRTDRTMVFYENKENLSKLWDILAVYAWIDKDVGYCQG 939
            E + +K + ++ L   +I  D+ R+      ++N+  ++ L  +L  YA+ + ++GYCQ 
Sbjct: 543  EGLVEKSMGKYNLATEEIERDLHRSLPEHPAFQNEMGIAALRRVLTAYAFRNPNIGYCQA 602

Query: 940  MSDLCSPMIVLLNDEADAFWCFEKLMRRLRGNFRCTDQSVGVANQLQHLASIIQVLDPKL 1119
            M ++ + +++L   E +AFW    L  R+  ++  T + VG          + +   P+L
Sbjct: 603  M-NIVTSVLLLYAKEEEAFWLLVALCERMLPDYYNT-RVVGALVDQGVFEELARDYVPQL 660

Query: 1120 HDHLETLG 1143
            +D ++ LG
Sbjct: 661  YDCMQDLG 668

---

>Q6ZT07:TBCD9_HUMAN TBC1 domain family member 9 - Homo sapiens (Human)|
          Length = 1266

 Score = 48.5 bits (114), Expect = 9e-05
 Identities = 31/128 (24%), Positives = 66/128 (51%)
 Frame = +1

Query: 760  ERITDKQIIEWKLTLHQIGLDVLRTDRTMVFYENKENLSKLWDILAVYAWIDKDVGYCQG 939
            E + +K + ++ L   +I  D+ R+      ++N+  ++ L  +L  YA+ + ++GYCQ 
Sbjct: 543  EDLVEKSMGKYNLATEEIERDLHRSLPEHPAFQNEMGIAALRRVLTAYAFRNPNIGYCQA 602

Query: 940  MSDLCSPMIVLLNDEADAFWCFEKLMRRLRGNFRCTDQSVGVANQLQHLASIIQVLDPKL 1119
            M ++ + +++L   E +AFW    L  R+  ++  T + VG          + +   P+L
Sbjct: 603  M-NIVTSVLLLYAKEEEAFWLLVALCERMLPDYYNT-RVVGALVDQGVFEELARDYVPQL 660

Query: 1120 HDHLETLG 1143
            +D ++ LG
Sbjct: 661  YDCMQDLG 668

---

>Q9BXI6:TB10A_HUMAN TBC1 domain family member 10A - Homo sapiens (Human)|
          Length = 508

 Score = 48.1 bits (113), Expect = 1e-04
 Identities = 36/149 (24%), Positives = 67/149 (44%), Gaps = 8/149 (5%)
 Frame = +1

Query: 817  LDVLRTD--RTMVFYE-----NKENLSKLWDILAVYAWIDKDVGYCQGMSDLCSPMIVLL 975
            LDV+  D  R   F+E            L+ +L  Y     + GYCQ  + + + +++ +
Sbjct: 151  LDVIERDLHRQFPFHEMFVSRGGHGQQDLFRVLKAYTLYRPEEGYCQAQAPIAAVLLMHM 210

Query: 976  NDEADAFWCFEKLMRR-LRGNFRCTDQSVGVANQLQHLASIIQVLDPKLHDHLETLGGGD 1152
              E  AFWC  ++  + L G +    +++ +  ++  L S++Q + P  H HL       
Sbjct: 211  PAE-QAFWCLVQICEKYLPGYYSEKLEAIQLDGEI--LFSLLQKVSPVAHKHLSRQKIDP 267

Query: 1153 YLFAFRMFMVLFRREVSFGDSLYLWEMMW 1239
             L+    FM  F R + +   L +W+M +
Sbjct: 268  LLYMTEWFMCAFSRTLPWSSVLRVWDMFF 296

---

>P58802:TB10A_MOUSE TBC1 domain family member 10A - Mus musculus (Mouse)|
          Length = 500

 Score = 47.8 bits (112), Expect = 2e-04
 Identities = 36/149 (24%), Positives = 67/149 (44%), Gaps = 8/149 (5%)
 Frame = +1

Query: 817  LDVLRTD--RTMVFYE-----NKENLSKLWDILAVYAWIDKDVGYCQGMSDLCSPMIVLL 975
            LDV+  D  R   F+E            L+ +L  Y     + GYCQ  + + + +++ +
Sbjct: 151  LDVIERDLHRQFPFHEMFVSRGGHGQQDLFRVLKAYTLYRPEEGYCQAQAPIAAVLLMHM 210

Query: 976  NDEADAFWCFEKLMRR-LRGNFRCTDQSVGVANQLQHLASIIQVLDPKLHDHLETLGGGD 1152
              E  AFWC  ++  + L G +    +++ +  ++  L S++Q + P  H HL       
Sbjct: 211  PAE-QAFWCLVQVCEKYLPGYYSEKLEAIQLDGEI--LFSLLQKVSPVAHKHLSRQKIDP 267

Query: 1153 YLFAFRMFMVLFRREVSFGDSLYLWEMMW 1239
             L+    FM  F R + +   L +W+M +
Sbjct: 268  LLYMTEWFMCAFARTLPWSSVLRVWDMFF 296

---

>Q5SVR0:TBC9B_MOUSE TBC1 domain family member 9B - Mus musculus (Mouse)|
          Length = 1263

 Score = 47.0 bits (110), Expect = 3e-04
 Identities = 29/126 (23%), Positives = 64/126 (50%)
 Frame = +1

Query: 766  ITDKQIIEWKLTLHQIGLDVLRTDRTMVFYENKENLSKLWDILAVYAWIDKDVGYCQGMS 945
            + +K + ++ L   +I  D+ R+      ++N+  ++ L  +L  YA+ +  +GYCQ M 
Sbjct: 539  LVEKSLGKYSLATEEIERDLHRSMPEHPAFQNELGIAALRRVLTAYAFRNPTIGYCQAM- 597

Query: 946  DLCSPMIVLLNDEADAFWCFEKLMRRLRGNFRCTDQSVGVANQLQHLASIIQVLDPKLHD 1125
            ++ + +++L   E +AFW    L  R+  ++  T + VG          + + + P+L +
Sbjct: 598  NIVTSVLLLYGSEEEAFWLLVALCERMLPDYYNT-RVVGALVDQGIFEELTRDVLPRLSE 656

Query: 1126 HLETLG 1143
             ++ LG
Sbjct: 657  KMQELG 662

---

>Q8C9V1:TB10C_MOUSE Carabin - Mus musculus (Mouse)|
          Length = 444

 Score = 46.2 bits (108), Expect = 5e-04
 Identities = 29/118 (24%), Positives = 59/118 (50%), Gaps = 1/118 (0%)
 Frame = +1

Query: 880  LWDILAVYAWIDKDVGYCQGMSDLCSPMIVLLNDEADAFWCFEKLMR-RLRGNFRCTDQS 1056
            L  +L  Y     + GYCQ    + + +++ L  E +AFWC  ++    L G +    ++
Sbjct: 158  LLQVLKAYTLYRPEQGYCQAQGPVAAVLLMHLPPE-EAFWCLVQICEVYLPGYYGPHMEA 216

Query: 1057 VGVANQLQHLASIIQVLDPKLHDHLETLGGGDYLFAFRMFMVLFRREVSFGDSLYLWE 1230
            V +  ++    ++++   P+++ HL+ +G G  L+    F+ LF R + F   L +W+
Sbjct: 217  VQLDAEV--FMALLRRQLPRVYKHLQQVGVGPLLYLPEWFLCLFTRSLPFPTVLRIWD 272

---

>P35125:UBP6_HUMAN Ubiquitin carboxyl-terminal hydrolase 6 - Homo sapiens (Human)|
          Length = 1406

 Score = 45.8 bits (107), Expect = 6e-04
 Identities = 39/151 (25%), Positives = 70/151 (46%), Gaps = 7/151 (4%)
 Frame = +1

Query: 802  LHQIGLDVLRTDRTMVFYENKENLSK--LWDILAVYAWIDKDVGYCQGMSDLCSPMIVLL 975
            +H I LDV  T R  VF+ ++    +  L+ IL  Y+  + +VGYC+ +S + +  ++ L
Sbjct: 141  IHHIDLDVRTTLRNHVFFRDRYGAKQRELFYILLAYSEYNPEVGYCRDLSHITALFLLYL 200

Query: 976  NDEADAFWCFEKLM---RRLRGNFRCTDQSV--GVANQLQHLASIIQVLDPKLHDHLETL 1140
             +E DAFW   +L+   R     F   +     G+ +Q +H   ++    PK   H +  
Sbjct: 201  PEE-DAFWALVQLLASERHSLPGFHSPNGGTVQGLQDQQEH---VVPKSQPKTMWHQDKE 256

Query: 1141 GGGDYLFAFRMFMVLFRREVSFGDSLYLWEM 1233
            G      +    +      +S G +L LW++
Sbjct: 257  GLCGQCASLGCLLRNLIDGISLGLTLRLWDV 287

---

>Q66K14:TBC9B_HUMAN TBC1 domain family member 9B - Homo sapiens (Human)|
          Length = 1250

 Score = 45.1 bits (105), Expect = 0.001
 Identities = 29/126 (23%), Positives = 62/126 (49%)
 Frame = +1

Query: 766  ITDKQIIEWKLTLHQIGLDVLRTDRTMVFYENKENLSKLWDILAVYAWIDKDVGYCQGMS 945
            + +K   ++ L   +I  D+ R+      ++N+  ++ L  +L  YA+ +  +GYCQ M 
Sbjct: 538  LVEKSTGKYSLATEEIERDLHRSMPEHPAFQNELGIAALRRVLTAYAFRNPTIGYCQAM- 596

Query: 946  DLCSPMIVLLNDEADAFWCFEKLMRRLRGNFRCTDQSVGVANQLQHLASIIQVLDPKLHD 1125
            ++ + +++L   E +AFW    L  R+  ++  T + VG          + +   P+L +
Sbjct: 597  NIVTSVLLLYGSEEEAFWLLVALCERMLPDYYNT-RVVGALVDQGIFEELTRDFLPQLSE 655

Query: 1126 HLETLG 1143
             ++ LG
Sbjct: 656  KMQDLG 661

---

>O60347:TBC12_HUMAN TBC1 domain family member 12 - Homo sapiens (Human)|
          Length = 775

 Score = 43.5 bits (101), Expect = 0.003
 Identities = 35/104 (33%), Positives = 51/104 (49%), Gaps = 1/104 (0%)
 Frame = +1

Query: 715  ASTSSNNGIEVDDSAERITDKQIIEWKLTLHQIGLDVLRTDRTM-VFYENKENLSKLWDI 891
            + TSS N  E    A+R         + +L  I LD+ RT  ++ +F +       L  I
Sbjct: 524  SETSSENDTEGVSVADR---------EASLELIKLDISRTFPSLYIFQKGGPYHDVLHSI 574

Query: 892  LAVYAWIDKDVGYCQGMSDLCSPMIVLLNDEADAFWCFEKLMRR 1023
            L  Y     DVGY QGMS + + +I+ L +EADAF  F  L+ +
Sbjct: 575  LGAYTCYRPDVGYVQGMSFIAAVLILNL-EEADAFIAFANLLNK 617

---

>Q8CGA2:TBC14_MOUSE TBC1 domain family member 14 - Mus musculus (Mouse)|
          Length = 679

 Score = 42.4 bits (98), Expect = 0.007
 Identities = 31/102 (30%), Positives = 50/102 (49%), Gaps = 1/102 (0%)
 Frame = +1

Query: 721  TSSNNGIEVDDSAERITDKQIIEWKLTLHQIGLDVLRTDRTM-VFYENKENLSKLWDILA 897
            ++  + +E +D+     D++      +L  I LD+ RT   + +F +       L  IL 
Sbjct: 427  STGGSEVENEDAGFSAADREA-----SLELIKLDISRTFPNLCIFQQGGPYHDMLHSILG 481

Query: 898  VYAWIDKDVGYCQGMSDLCSPMIVLLNDEADAFWCFEKLMRR 1023
             Y     DVGY QGMS + + +I+ L D ADAF  F  L+ +
Sbjct: 482  AYTCYRPDVGYVQGMSFIAAVLILNL-DTADAFIAFSNLLNK 522

---

>Q9P2M4:TBC14_HUMAN TBC1 domain family member 14 - Homo sapiens (Human)|
          Length = 678

 Score = 42.4 bits (98), Expect = 0.007
 Identities = 31/102 (30%), Positives = 50/102 (49%), Gaps = 1/102 (0%)
 Frame = +1

Query: 721  TSSNNGIEVDDSAERITDKQIIEWKLTLHQIGLDVLRTDRTM-VFYENKENLSKLWDILA 897
            ++  + +E +D+     D++      +L  I LD+ RT   + +F +       L  IL 
Sbjct: 426  STGGSEVENEDAGFSAADREA-----SLELIKLDISRTFPNLCIFQQGGPYHDMLHSILG 480

Query: 898  VYAWIDKDVGYCQGMSDLCSPMIVLLNDEADAFWCFEKLMRR 1023
             Y     DVGY QGMS + + +I+ L D ADAF  F  L+ +
Sbjct: 481  AYTCYRPDVGYVQGMSFIAAVLILNL-DTADAFIAFSNLLNK 521

---

>Q9Z1A9:TBCD8_MOUSE TBC1 domain family member 8 - Mus musculus (Mouse)|
          Length = 891

 Score = 41.2 bits (95), Expect = 0.015
 Identities = 28/115 (24%), Positives = 55/115 (47%)
 Frame = +1

Query: 796  LTLHQIGLDVLRTDRTMVFYENKENLSKLWDILAVYAWIDKDVGYCQGMSDLCSPMIVLL 975
            L   +I  D+ R+      ++N+  ++ L  +L  YA  +  +GYCQ M+ L S +++L 
Sbjct: 301  LVTEEIERDLHRSLPEHPAFQNETGIAALRRVLTAYAHRNPKIGYCQSMNILTS-VLLLY 359

Query: 976  NDEADAFWCFEKLMRRLRGNFRCTDQSVGVANQLQHLASIIQVLDPKLHDHLETL 1140
              E +AFW    +  R+  ++    + +G          +I+   P+L +H+  L
Sbjct: 360  AKEEEAFWLLVAVCERMLPDY-FNHRVIGAQVDQSVFEELIKEQLPELAEHMSDL 413

---

>O95759:TBCD8_HUMAN TBC1 domain family member 8 - Homo sapiens (Human)|
          Length = 897

 Score = 41.2 bits (95), Expect = 0.015
 Identities = 28/115 (24%), Positives = 55/115 (47%)
 Frame = +1

Query: 796  LTLHQIGLDVLRTDRTMVFYENKENLSKLWDILAVYAWIDKDVGYCQGMSDLCSPMIVLL 975
            L   +I  D+ R+      ++N+  ++ L  +L  YA  +  +GYCQ M+ L S +++L 
Sbjct: 302  LVTEEIERDLHRSLPEHPAFQNETGIAALRRVLTAYAHRNPKIGYCQSMNILTS-VLLLY 360

Query: 976  NDEADAFWCFEKLMRRLRGNFRCTDQSVGVANQLQHLASIIQVLDPKLHDHLETL 1140
              E +AFW    +  R+  ++    + +G          +I+   P+L +H+  L
Sbjct: 361  TKEEEAFWLLVAVCERMLPDY-FNHRVIGAQVDQSVFEELIKGHLPELAEHMNDL 414

---

>Q09445:YQ01_CAEEL Uncharacterized protein C04A2.1 - Caenorhabditis elegans|
          Length = 330

 Score = 40.8 bits (94), Expect = 0.020
 Identities = 34/145 (23%), Positives = 65/145 (44%)
 Frame = +1

Query: 802  LHQIGLDVLRTDRTMVFYENKENLSKLWDILAVYAWIDKDVGYCQGMSDLCSPMIVLLND 981
            + QI LD+ RT     F + +     L   L   A     VGYCQG++ +   +++++ND
Sbjct: 110  IKQIKLDLPRTFPDNKFLKTEGTRKTLGRALFAVAEHIPSVGYCQGLNFVAGVILLVVND 169

Query: 982  EADAFWCFEKLMRRLRGNFRCTDQSVGVANQLQHLASIIQVLDPKLHDHLETLGGGDYLF 1161
            E+ A      L+ + +  +      +G+   +  L S+++   P++   LE L  G  + 
Sbjct: 170  ESRAIDLLVHLVSQRQEYY--GKNMIGLRRDMHVLHSLLREHCPRVVVTLEKLDVGLDML 227

Query: 1162 AFRMFMVLFRREVSFGDSLYLWEMM 1236
              + F+  F   +     L LW+ +
Sbjct: 228  VGKWFVCWFVESLPMETVLRLWDCL 252

---

>Q8IZP1:TBCD3_HUMAN TBC1 domain family member 3 - Homo sapiens (Human)|
          Length = 549

 Score = 40.4 bits (93), Expect = 0.026
 Identities = 37/151 (24%), Positives = 69/151 (45%), Gaps = 7/151 (4%)
 Frame = +1

Query: 802  LHQIGLDVLRTDRTMVFYENKENLSK--LWDILAVYAWIDKDVGYCQGMSDLCSPMIVLL 975
            + +I  DV  T R  +F+ ++    +  L  IL  Y   + +VGYC+ +S + +  ++ L
Sbjct: 142  IQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYL 201

Query: 976  NDEADAFWCFEKLM----RRLRGNFRCTDQSV-GVANQLQHLASIIQVLDPKLHDHLETL 1140
             +E DAFW   +L+      L+G       +V G+ +Q +H+ +  Q   PK   H +  
Sbjct: 202  PEE-DAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQ---PKTMGHQDKK 257

Query: 1141 GGGDYLFAFRMFMVLFRREVSFGDSLYLWEM 1233
                        + +    +S G +L LW++
Sbjct: 258  DLCGQCSPLGCLIRILIDGISLGLTLRLWDV 288

---

>Q9D3N8:GRTP1_MOUSE Growth hormone-regulated TBC protein 1 - Mus musculus (Mouse)|
          Length = 359

 Score = 40.4 bits (93), Expect = 0.026
 Identities = 36/165 (21%), Positives = 73/165 (44%), Gaps = 25/165 (15%)
 Frame = +1

Query: 820  DVLRTDRTMVFYEN-------KENLSK-LWDILAVYAWIDKDVGYCQ------------- 936
            + +RTD    F +N          L K L+++L  Y   + DVGYCQ             
Sbjct: 115  EAIRTDLNRTFPDNVMFRKTADPCLQKTLYNVLLAYGLHNPDVGYCQCCAQKPGSSAGLR 174

Query: 937  ----GMSDLCSPMIVLLNDEADAFWCFEKLMRRLRGNFRCTDQSVGVANQLQHLASIIQV 1104
                GM+ +   +I++  +E ++FW  + L+ R+  ++  +   +G+    + LA ++++
Sbjct: 175  SSLTGMNFIAGYLILITKNEEESFWLLDALVGRILPDY-YSPAMLGLKTDQEVLAELVRM 233

Query: 1105 LDPKLHDHLETLGGGDYLFAFRMFMVLFRREVSFGDSLYLWEMMW 1239
              P +   ++  G    L   R F+ LF   +     L +W+ ++
Sbjct: 234  KLPAVAALMDGHGVLWTLLVSRWFICLFVDILPVETVLRIWDCLF 278

---

>Q80XQ2:TBCD5_MOUSE TBC1 domain family member 5 - Mus musculus (Mouse)|
          Length = 815

 Score = 38.9 bits (89), Expect = 0.075
 Identities = 46/194 (23%), Positives = 72/194 (37%), Gaps = 53/194 (27%)
 Frame = +1

Query: 820  DVLRTDRTMVFYENKENLSKLWDILAVYAWIDKDVGYCQGMSDLCSPMI----------- 966
            DV RT   M F++ +     L D+L  YA  ++ + Y QGM +L +P+I           
Sbjct: 166  DVKRTFPEMQFFQQENVRKILTDVLFCYARENEQLLYKQGMHELLAPIIFTLHCDHQAFL 225

Query: 967  -------------VLLND---EADAFWCFEKLMRRLRGNFRCTDQS-------------- 1056
                          LLN    E DA+  F +LM      F   +                
Sbjct: 226  HASESAQPSEEMKTLLNPEYLEHDAYAMFSQLMETAEPWFSTFEHDGQKGKETLMAPIPF 285

Query: 1057 ------------VGVANQLQHLASIIQVLDPKLHDHLETLGGGDYLFAFRMFMVLFRREV 1200
                        V   NQ+Q    +++  D +L+ HL  L     ++  R   +LF RE 
Sbjct: 286  ARPQDLGPTVAIVTKVNQIQD--HLLKKHDIELYMHLNRLEIAPQIYGLRWVRLLFGREF 343

Query: 1201 SFGDSLYLWEMMWA 1242
               D L +W+ ++A
Sbjct: 344  PLQDLLVVWDALFA 357

---

>Q92609:TBCD5_HUMAN TBC1 domain family member 5 - Homo sapiens (Human)|
          Length = 795

 Score = 38.5 bits (88), Expect = 0.098
 Identities = 43/194 (22%), Positives = 72/194 (37%), Gaps = 53/194 (27%)
 Frame = +1

Query: 820  DVLRTDRTMVFYENKENLSKLWDILAVYAWIDKDVGYCQGMSDLCSPMIVLLND------ 981
            DV RT   M F++ +     L D+L  YA  ++ + Y QGM +L +P++ +L+       
Sbjct: 166  DVKRTFPEMQFFQQENVRKILTDVLFCYARENEQLLYKQGMHELLAPIVFVLHCDHQAFL 225

Query: 982  ---------------------EADAFWCFEKLMRRLRGNFRCTDQS-------------- 1056
                                 E DA+  F +LM      F   +                
Sbjct: 226  HASESAQPSEEMKTVLNPEYLEHDAYAVFSQLMETAEPWFSTFEHDGQKGKETLMTPIPF 285

Query: 1057 ------------VGVANQLQHLASIIQVLDPKLHDHLETLGGGDYLFAFRMFMVLFRREV 1200
                        V   NQ+Q    +++  D +L+ HL  L     ++  R   +LF RE 
Sbjct: 286  ARPQDLGPTIAIVTKVNQIQD--HLLKKHDIELYMHLNRLEIAPQIYGLRWVRLLFGREF 343

Query: 1201 SFGDSLYLWEMMWA 1242
               D L +W+ ++A
Sbjct: 344  PLQDLLVVWDALFA 357

---

>Q8IX21:CJ006_HUMAN Uncharacterized protein C10orf6 - Homo sapiens (Human)|
          Length = 1173

 Score = 36.2 bits (82), Expect = 0.49
 Identities = 22/63 (34%), Positives = 33/63 (52%), Gaps = 9/63 (14%)
 Frame = +1

Query: 574 KEECREMDSHVGSGKVITAPLITEDGRPIKDPLVLLE---------ATSNQNTSDGASTS 726
           K +  + DS+V SGK+   PL +E G P K P   LE         A S++  S+G S+ 
Sbjct: 525 KAKTNKADSNVSSGKISGGPLRSEYGTPTKSPPAALEVVPCIPSPAAPSDKAPSEGESSG 584

Query: 727 SNN 735
           ++N
Sbjct: 585 NSN 587

---

>Q2T9Q1:TBC20_BOVIN TBC1 domain family member 20 - Bos taurus (Bovine)|
          Length = 403

 Score = 34.3 bits (77), Expect = 1.8
 Identities = 44/175 (25%), Positives = 77/175 (44%), Gaps = 5/175 (2%)
 Frame = +1

Query: 766  ITDKQIIEWKLTLHQIGLDVLRTDRTM---VFYENKENLSK-LWDILAVYAWIDKDVGYC 933
            I+ K + +      Q+ LDV R+ R     +  E +E L + L DI+ +    +  + Y 
Sbjct: 84   ISGKNLRQMSKDYQQVLLDVRRSLRRFPPGMPEEQREGLQEELIDIILLILERNPQLHYY 143

Query: 934  QGMSDLCSPMIVLLNDEADAFWCFEKLMRRLRGNFRCTDQSVGVANQLQHLASIIQVLDP 1113
            QG  D+    +++L +   A    EKL      +F          + L +L  II  ++P
Sbjct: 144  QGYHDIVVTFLLVLGERL-ATSLVEKLSTHHLRDFMDPTMD-NTKHILNYLMPIIDQVNP 201

Query: 1114 KLHDHLETLGGGDYLFAFRMFMVLFRREVS-FGDSLYLWEMMWALEYDPDIFFAA 1275
            +LHD +++   G  +FA    +  F   +S F   + L++   A      I+FAA
Sbjct: 202  ELHDFMQSAEVGT-IFALSWLITWFGHVLSDFRHVVRLYDFFLACHPLMPIYFAA 255

---

>Q5REF4:CJ006_PONPY Uncharacterized protein C10orf6 homolog - Pongo pygmaeus|
           (Orangutan)
          Length = 1174

 Score = 33.9 bits (76), Expect = 2.4
 Identities = 21/63 (33%), Positives = 32/63 (50%), Gaps = 9/63 (14%)
 Frame = +1

Query: 574 KEECREMDSHVGSGKVITAPLITEDGRPIKDPLVLLE---------ATSNQNTSDGASTS 726
           K +  + DS+V SGK+   PL +E G P K P   LE         A S++  S+  S+ 
Sbjct: 526 KAKTNKADSNVSSGKISGGPLCSEYGAPTKSPPAALEVVPCVPSPAAPSDKAPSERESSG 585

Query: 727 SNN 735
           ++N
Sbjct: 586 NSN 588

---

>Q96BZ9:TBC20_HUMAN TBC1 domain family member 20 - Homo sapiens (Human)|
          Length = 403

 Score = 33.1 bits (74), Expect = 4.1
 Identities = 43/175 (24%), Positives = 77/175 (44%), Gaps = 5/175 (2%)
 Frame = +1

Query: 766  ITDKQIIEWKLTLHQIGLDVLRTDRTM---VFYENKENLSK-LWDILAVYAWIDKDVGYC 933
            I+ K + +      Q+ LDV R+ R     +  E +E L + L DI+ +    +  + Y 
Sbjct: 84   ISGKNLRQMSKDYQQVLLDVRRSLRRFPPGMPEEQREGLQEELIDIILLILERNPQLHYY 143

Query: 934  QGMSDLCSPMIVLLNDEADAFWCFEKLMRRLRGNFRCTDQSVGVANQLQHLASIIQVLDP 1113
            QG  D+    ++++ +   A    EKL      +F          + L +L  II  ++P
Sbjct: 144  QGYHDIVVTFLLVVGERL-ATSLVEKLSTHHLRDFMDPTMD-NTKHILNYLMPIIDQVNP 201

Query: 1114 KLHDHLETLGGGDYLFAFRMFMVLFRREVS-FGDSLYLWEMMWALEYDPDIFFAA 1275
            +LHD +++   G  +FA    +  F   +S F   + L++   A      I+FAA
Sbjct: 202  ELHDFMQSAEVGT-IFALSWLITWFGHVLSDFRHVVRLYDFFLACHPLMPIYFAA 255

---

>Q12317:MSB4_YEAST GTPase-activating protein MSB4 - Saccharomyces cerevisiae (Baker's|
           yeast)
          Length = 492

 Score = 32.7 bits (73), Expect = 5.4
 Identities = 14/37 (37%), Positives = 23/37 (62%)
 Frame = +1

Query: 889 ILAVYAWIDKDVGYCQGMSDLCSPMIVLLNDEADAFW 999
           +L  ++  DK +GYCQ M+ L   +++L  +E  AFW
Sbjct: 227 VLMAFSVYDKTIGYCQSMNFLVG-LLLLFMEEEKAFW 262

---

>P48566:GYP3_YEAST GTPase-activating protein GYP3 - Saccharomyces cerevisiae (Baker's|
           yeast)
          Length = 633

 Score = 32.3 bits (72), Expect = 7.0
 Identities = 21/73 (28%), Positives = 34/73 (46%), Gaps = 12/73 (16%)
 Frame = +1

Query: 817 LDVLRTDRTMVFYEN---------KEN---LSKLWDILAVYAWIDKDVGYCQGMSDLCSP 960
           LD++  D    F +N         KE    +  L  +L  ++  +  +GYCQ M+ L   
Sbjct: 273 LDIIERDLNRTFPDNIHFQSSLHNKEGPPIIKSLRRVLVAFSLYNPKIGYCQSMNFLAG- 331

Query: 961 MIVLLNDEADAFW 999
           +++L  DE  AFW
Sbjct: 332 LLLLFLDEERAFW 344


  Database: uniprot_sprot.fasta.out
    Posted date:  Jul 19, 2007  5:58 PM
  Number of letters in database: 100,686,439
  Number of sequences in database:  274,295
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 274295
Number of Hits to DB: 319,701,030
Number of extensions: 6970228
Number of successful extensions: 19274
Number of sequences better than 10.0: 70
Number of HSP's gapped: 19206
Number of HSP's successfully gapped: 83
Length of query: 624
Length of database: 100,686,439
Length adjustment: 119
Effective length of query: 505
Effective length of database: 68,045,334
Effective search space: 34362893670
Effective search space used: 34362893670
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

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